data_9BO4
# 
_entry.id   9BO4 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BO4         pdb_00009bo4 10.2210/pdb9bo4/pdb 
WWPDB D_1000282931 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-12 ? 
2 'Structure model' 1 1 2025-03-12 ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
_pdbx_audit_revision_category.ordinal             1 
_pdbx_audit_revision_category.revision_ordinal    2 
_pdbx_audit_revision_category.data_content_type   'Structure model' 
_pdbx_audit_revision_category.category            citation 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
5 2 'Structure model' '_citation.title'                   
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BO4 
_pdbx_database_status.recvd_initial_deposition_date   2024-05-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              karen.anderson@yale.edu 
_pdbx_contact_author.name_first         Karen 
_pdbx_contact_author.name_last          Anderson 
_pdbx_contact_author.name_mi            S 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0003-3433-0780 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Papini, C.'     1 0000-0002-6098-4959 
'Anderson, K.S.' 2 0000-0003-3433-0780 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Acs Bio Med Chem Au' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2694-2437 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            5 
_citation.language                  ? 
_citation.page_first                215 
_citation.page_last                 226 
_citation.title                     
'Exploring Possible Drug-Resistant Variants of SARS-CoV-2 Main Protease (M pro ) with Noncovalent Preclinical Candidate, Mpro61.' 
_citation.year                      2025 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1021/acsbiomedchemau.4c00109 
_citation.pdbx_database_id_PubMed   39990941 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kenneson, J.R.'  1 ? 
primary 'Papini, C.'      2 ? 
primary 'Tang, S.'        3 ? 
primary 'Huynh, K.'       4 ? 
primary 'Zhang, C.H.'     5 ? 
primary 'Jorgensen, W.L.' 6 ? 
primary 'Anderson, K.S.'  7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man '3C-like proteinase' 33837.602 2  3.4.22.69 ? ? ? 
2 non-polymer syn 
;(1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
;
501.542   2  ?         ? ? ? 
3 water       nat water 18.015    57 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '3CL-PRO, 3CLp, Main protease, Mpro, Non-structural protein 5, nsp5, SARS coronavirus main proteinase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;SGFRKMAFPSGKVEGCMVQVICGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_seq_one_letter_code_can   
;SGFRKMAFPSGKVEGCMVQVICGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 
;(1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
;
4WI 
3 water HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER n 
1 2   GLY n 
1 3   PHE n 
1 4   ARG n 
1 5   LYS n 
1 6   MET n 
1 7   ALA n 
1 8   PHE n 
1 9   PRO n 
1 10  SER n 
1 11  GLY n 
1 12  LYS n 
1 13  VAL n 
1 14  GLU n 
1 15  GLY n 
1 16  CYS n 
1 17  MET n 
1 18  VAL n 
1 19  GLN n 
1 20  VAL n 
1 21  ILE n 
1 22  CYS n 
1 23  GLY n 
1 24  THR n 
1 25  THR n 
1 26  THR n 
1 27  LEU n 
1 28  ASN n 
1 29  GLY n 
1 30  LEU n 
1 31  TRP n 
1 32  LEU n 
1 33  ASP n 
1 34  ASP n 
1 35  VAL n 
1 36  VAL n 
1 37  TYR n 
1 38  CYS n 
1 39  PRO n 
1 40  ARG n 
1 41  HIS n 
1 42  VAL n 
1 43  ILE n 
1 44  CYS n 
1 45  THR n 
1 46  SER n 
1 47  GLU n 
1 48  ASP n 
1 49  MET n 
1 50  LEU n 
1 51  ASN n 
1 52  PRO n 
1 53  ASN n 
1 54  TYR n 
1 55  GLU n 
1 56  ASP n 
1 57  LEU n 
1 58  LEU n 
1 59  ILE n 
1 60  ARG n 
1 61  LYS n 
1 62  SER n 
1 63  ASN n 
1 64  HIS n 
1 65  ASN n 
1 66  PHE n 
1 67  LEU n 
1 68  VAL n 
1 69  GLN n 
1 70  ALA n 
1 71  GLY n 
1 72  ASN n 
1 73  VAL n 
1 74  GLN n 
1 75  LEU n 
1 76  ARG n 
1 77  VAL n 
1 78  ILE n 
1 79  GLY n 
1 80  HIS n 
1 81  SER n 
1 82  MET n 
1 83  GLN n 
1 84  ASN n 
1 85  CYS n 
1 86  VAL n 
1 87  LEU n 
1 88  LYS n 
1 89  LEU n 
1 90  LYS n 
1 91  VAL n 
1 92  ASP n 
1 93  THR n 
1 94  ALA n 
1 95  ASN n 
1 96  PRO n 
1 97  LYS n 
1 98  THR n 
1 99  PRO n 
1 100 LYS n 
1 101 TYR n 
1 102 LYS n 
1 103 PHE n 
1 104 VAL n 
1 105 ARG n 
1 106 ILE n 
1 107 GLN n 
1 108 PRO n 
1 109 GLY n 
1 110 GLN n 
1 111 THR n 
1 112 PHE n 
1 113 SER n 
1 114 VAL n 
1 115 LEU n 
1 116 ALA n 
1 117 CYS n 
1 118 TYR n 
1 119 ASN n 
1 120 GLY n 
1 121 SER n 
1 122 PRO n 
1 123 SER n 
1 124 GLY n 
1 125 VAL n 
1 126 TYR n 
1 127 GLN n 
1 128 CYS n 
1 129 ALA n 
1 130 MET n 
1 131 ARG n 
1 132 PRO n 
1 133 ASN n 
1 134 PHE n 
1 135 THR n 
1 136 ILE n 
1 137 LYS n 
1 138 GLY n 
1 139 SER n 
1 140 PHE n 
1 141 LEU n 
1 142 ASN n 
1 143 GLY n 
1 144 SER n 
1 145 CYS n 
1 146 GLY n 
1 147 SER n 
1 148 VAL n 
1 149 GLY n 
1 150 PHE n 
1 151 ASN n 
1 152 ILE n 
1 153 ASP n 
1 154 TYR n 
1 155 ASP n 
1 156 CYS n 
1 157 VAL n 
1 158 SER n 
1 159 PHE n 
1 160 CYS n 
1 161 TYR n 
1 162 MET n 
1 163 HIS n 
1 164 HIS n 
1 165 MET n 
1 166 GLU n 
1 167 LEU n 
1 168 PRO n 
1 169 THR n 
1 170 GLY n 
1 171 VAL n 
1 172 HIS n 
1 173 ALA n 
1 174 GLY n 
1 175 THR n 
1 176 ASP n 
1 177 LEU n 
1 178 GLU n 
1 179 GLY n 
1 180 ASN n 
1 181 PHE n 
1 182 TYR n 
1 183 GLY n 
1 184 PRO n 
1 185 PHE n 
1 186 VAL n 
1 187 ASP n 
1 188 ARG n 
1 189 GLN n 
1 190 THR n 
1 191 ALA n 
1 192 GLN n 
1 193 ALA n 
1 194 ALA n 
1 195 GLY n 
1 196 THR n 
1 197 ASP n 
1 198 THR n 
1 199 THR n 
1 200 ILE n 
1 201 THR n 
1 202 VAL n 
1 203 ASN n 
1 204 VAL n 
1 205 LEU n 
1 206 ALA n 
1 207 TRP n 
1 208 LEU n 
1 209 TYR n 
1 210 ALA n 
1 211 ALA n 
1 212 VAL n 
1 213 ILE n 
1 214 ASN n 
1 215 GLY n 
1 216 ASP n 
1 217 ARG n 
1 218 TRP n 
1 219 PHE n 
1 220 LEU n 
1 221 ASN n 
1 222 ARG n 
1 223 PHE n 
1 224 THR n 
1 225 THR n 
1 226 THR n 
1 227 LEU n 
1 228 ASN n 
1 229 ASP n 
1 230 PHE n 
1 231 ASN n 
1 232 LEU n 
1 233 VAL n 
1 234 ALA n 
1 235 MET n 
1 236 LYS n 
1 237 TYR n 
1 238 ASN n 
1 239 TYR n 
1 240 GLU n 
1 241 PRO n 
1 242 LEU n 
1 243 THR n 
1 244 GLN n 
1 245 ASP n 
1 246 HIS n 
1 247 VAL n 
1 248 ASP n 
1 249 ILE n 
1 250 LEU n 
1 251 GLY n 
1 252 PRO n 
1 253 LEU n 
1 254 SER n 
1 255 ALA n 
1 256 GLN n 
1 257 THR n 
1 258 GLY n 
1 259 ILE n 
1 260 ALA n 
1 261 VAL n 
1 262 LEU n 
1 263 ASP n 
1 264 MET n 
1 265 CYS n 
1 266 ALA n 
1 267 SER n 
1 268 LEU n 
1 269 LYS n 
1 270 GLU n 
1 271 LEU n 
1 272 LEU n 
1 273 GLN n 
1 274 ASN n 
1 275 GLY n 
1 276 MET n 
1 277 ASN n 
1 278 GLY n 
1 279 ARG n 
1 280 THR n 
1 281 ILE n 
1 282 LEU n 
1 283 GLY n 
1 284 SER n 
1 285 ALA n 
1 286 LEU n 
1 287 LEU n 
1 288 GLU n 
1 289 ASP n 
1 290 GLU n 
1 291 PHE n 
1 292 THR n 
1 293 PRO n 
1 294 PHE n 
1 295 ASP n 
1 296 VAL n 
1 297 VAL n 
1 298 ARG n 
1 299 GLN n 
1 300 CYS n 
1 301 SER n 
1 302 GLY n 
1 303 VAL n 
1 304 THR n 
1 305 PHE n 
1 306 GLN n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   306 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
4WI non-polymer         . 
;(1R,2S,5S)-N-{(1E,2S)-1-imino-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}-6,6-dimethyl-3-[3-methyl-N-(trifluoroacetyl)-L-valyl]-3-azabicyclo[3.1.0]hexane-2-carboxamide
;
'PF-07321332, bound form; nirmatrelvir, bound form; Paxlovid, bound form' 'C23 H34 F3 N5 O4' 501.542 
ALA 'L-peptide linking' y ALANINE ?                                                                         'C3 H7 N O2'       
89.093  
ARG 'L-peptide linking' y ARGININE ?                                                                         'C6 H15 N4 O2 1'   
175.209 
ASN 'L-peptide linking' y ASPARAGINE ?                                                                         'C4 H8 N2 O3'      
132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ?                                                                         'C4 H7 N O4' 
133.103 
CYS 'L-peptide linking' y CYSTEINE ?                                                                         'C3 H7 N O2 S'     
121.158 
GLN 'L-peptide linking' y GLUTAMINE ?                                                                         'C5 H10 N2 O3'     
146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ?                                                                         'C5 H9 N O4' 
147.129 
GLY 'peptide linking'   y GLYCINE ?                                                                         'C2 H5 N O2'       
75.067  
HIS 'L-peptide linking' y HISTIDINE ?                                                                         'C6 H10 N3 O2 1'   
156.162 
HOH non-polymer         . WATER ?                                                                         'H2 O'             
18.015  
ILE 'L-peptide linking' y ISOLEUCINE ?                                                                         'C6 H13 N O2'      
131.173 
LEU 'L-peptide linking' y LEUCINE ?                                                                         'C6 H13 N O2'      
131.173 
LYS 'L-peptide linking' y LYSINE ?                                                                         'C6 H15 N2 O2 1'   
147.195 
MET 'L-peptide linking' y METHIONINE ?                                                                         'C5 H11 N O2 S'    
149.211 
PHE 'L-peptide linking' y PHENYLALANINE ?                                                                         'C9 H11 N O2' 
165.189 
PRO 'L-peptide linking' y PROLINE ?                                                                         'C5 H9 N O2'       
115.130 
SER 'L-peptide linking' y SERINE ?                                                                         'C3 H7 N O3'       
105.093 
THR 'L-peptide linking' y THREONINE ?                                                                         'C4 H9 N O3'       
119.119 
TRP 'L-peptide linking' y TRYPTOPHAN ?                                                                         'C11 H12 N2 O2'    
204.225 
TYR 'L-peptide linking' y TYROSINE ?                                                                         'C9 H11 N O3'      
181.189 
VAL 'L-peptide linking' y VALINE ?                                                                         'C5 H11 N O2'      
117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER 1   1   1   SER SER A . n 
A 1 2   GLY 2   2   2   GLY GLY A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   ARG 4   4   4   ARG ARG A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   MET 6   6   6   MET MET A . n 
A 1 7   ALA 7   7   7   ALA ALA A . n 
A 1 8   PHE 8   8   8   PHE PHE A . n 
A 1 9   PRO 9   9   9   PRO PRO A . n 
A 1 10  SER 10  10  10  SER SER A . n 
A 1 11  GLY 11  11  11  GLY GLY A . n 
A 1 12  LYS 12  12  12  LYS LYS A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  GLU 14  14  14  GLU GLU A . n 
A 1 15  GLY 15  15  15  GLY GLY A . n 
A 1 16  CYS 16  16  16  CYS CYS A . n 
A 1 17  MET 17  17  17  MET MET A . n 
A 1 18  VAL 18  18  18  VAL VAL A . n 
A 1 19  GLN 19  19  19  GLN GLN A . n 
A 1 20  VAL 20  20  20  VAL VAL A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  CYS 22  22  22  CYS CYS A . n 
A 1 23  GLY 23  23  23  GLY GLY A . n 
A 1 24  THR 24  24  24  THR THR A . n 
A 1 25  THR 25  25  25  THR THR A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  LEU 27  27  27  LEU LEU A . n 
A 1 28  ASN 28  28  28  ASN ASN A . n 
A 1 29  GLY 29  29  29  GLY GLY A . n 
A 1 30  LEU 30  30  30  LEU LEU A . n 
A 1 31  TRP 31  31  31  TRP TRP A . n 
A 1 32  LEU 32  32  32  LEU LEU A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ASP 34  34  34  ASP ASP A . n 
A 1 35  VAL 35  35  35  VAL VAL A . n 
A 1 36  VAL 36  36  36  VAL VAL A . n 
A 1 37  TYR 37  37  37  TYR TYR A . n 
A 1 38  CYS 38  38  38  CYS CYS A . n 
A 1 39  PRO 39  39  39  PRO PRO A . n 
A 1 40  ARG 40  40  40  ARG ARG A . n 
A 1 41  HIS 41  41  41  HIS HIS A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  ILE 43  43  43  ILE ILE A . n 
A 1 44  CYS 44  44  44  CYS CYS A . n 
A 1 45  THR 45  45  45  THR THR A . n 
A 1 46  SER 46  46  46  SER SER A . n 
A 1 47  GLU 47  47  47  GLU GLU A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  MET 49  49  49  MET MET A . n 
A 1 50  LEU 50  50  50  LEU LEU A . n 
A 1 51  ASN 51  51  51  ASN ASN A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  ASN 53  53  53  ASN ASN A . n 
A 1 54  TYR 54  54  54  TYR TYR A . n 
A 1 55  GLU 55  55  55  GLU GLU A . n 
A 1 56  ASP 56  56  56  ASP ASP A . n 
A 1 57  LEU 57  57  57  LEU LEU A . n 
A 1 58  LEU 58  58  58  LEU LEU A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ARG 60  60  60  ARG ARG A . n 
A 1 61  LYS 61  61  61  LYS LYS A . n 
A 1 62  SER 62  62  62  SER SER A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  HIS 64  64  64  HIS HIS A . n 
A 1 65  ASN 65  65  65  ASN ASN A . n 
A 1 66  PHE 66  66  66  PHE PHE A . n 
A 1 67  LEU 67  67  67  LEU LEU A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  GLN 69  69  69  GLN GLN A . n 
A 1 70  ALA 70  70  70  ALA ALA A . n 
A 1 71  GLY 71  71  71  GLY GLY A . n 
A 1 72  ASN 72  72  72  ASN ASN A . n 
A 1 73  VAL 73  73  73  VAL VAL A . n 
A 1 74  GLN 74  74  74  GLN GLN A . n 
A 1 75  LEU 75  75  75  LEU LEU A . n 
A 1 76  ARG 76  76  76  ARG ARG A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  ILE 78  78  78  ILE ILE A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  SER 81  81  81  SER SER A . n 
A 1 82  MET 82  82  82  MET MET A . n 
A 1 83  GLN 83  83  83  GLN GLN A . n 
A 1 84  ASN 84  84  84  ASN ASN A . n 
A 1 85  CYS 85  85  85  CYS CYS A . n 
A 1 86  VAL 86  86  86  VAL VAL A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  LYS 88  88  88  LYS LYS A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  LYS 90  90  90  LYS LYS A . n 
A 1 91  VAL 91  91  91  VAL VAL A . n 
A 1 92  ASP 92  92  92  ASP ASP A . n 
A 1 93  THR 93  93  93  THR THR A . n 
A 1 94  ALA 94  94  94  ALA ALA A . n 
A 1 95  ASN 95  95  95  ASN ASN A . n 
A 1 96  PRO 96  96  96  PRO PRO A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  THR 98  98  98  THR THR A . n 
A 1 99  PRO 99  99  99  PRO PRO A . n 
A 1 100 LYS 100 100 100 LYS LYS A . n 
A 1 101 TYR 101 101 101 TYR TYR A . n 
A 1 102 LYS 102 102 102 LYS LYS A . n 
A 1 103 PHE 103 103 103 PHE PHE A . n 
A 1 104 VAL 104 104 104 VAL VAL A . n 
A 1 105 ARG 105 105 105 ARG ARG A . n 
A 1 106 ILE 106 106 106 ILE ILE A . n 
A 1 107 GLN 107 107 107 GLN GLN A . n 
A 1 108 PRO 108 108 108 PRO PRO A . n 
A 1 109 GLY 109 109 109 GLY GLY A . n 
A 1 110 GLN 110 110 110 GLN GLN A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 PHE 112 112 112 PHE PHE A . n 
A 1 113 SER 113 113 113 SER SER A . n 
A 1 114 VAL 114 114 114 VAL VAL A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 ALA 116 116 116 ALA ALA A . n 
A 1 117 CYS 117 117 117 CYS CYS A . n 
A 1 118 TYR 118 118 118 TYR TYR A . n 
A 1 119 ASN 119 119 119 ASN ASN A . n 
A 1 120 GLY 120 120 120 GLY GLY A . n 
A 1 121 SER 121 121 121 SER SER A . n 
A 1 122 PRO 122 122 122 PRO PRO A . n 
A 1 123 SER 123 123 123 SER SER A . n 
A 1 124 GLY 124 124 124 GLY GLY A . n 
A 1 125 VAL 125 125 125 VAL VAL A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 GLN 127 127 127 GLN GLN A . n 
A 1 128 CYS 128 128 128 CYS CYS A . n 
A 1 129 ALA 129 129 129 ALA ALA A . n 
A 1 130 MET 130 130 130 MET MET A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 PRO 132 132 132 PRO PRO A . n 
A 1 133 ASN 133 133 133 ASN ASN A . n 
A 1 134 PHE 134 134 134 PHE PHE A . n 
A 1 135 THR 135 135 135 THR THR A . n 
A 1 136 ILE 136 136 136 ILE ILE A . n 
A 1 137 LYS 137 137 137 LYS LYS A . n 
A 1 138 GLY 138 138 138 GLY GLY A . n 
A 1 139 SER 139 139 139 SER SER A . n 
A 1 140 PHE 140 140 140 PHE PHE A . n 
A 1 141 LEU 141 141 141 LEU LEU A . n 
A 1 142 ASN 142 142 142 ASN ASN A . n 
A 1 143 GLY 143 143 143 GLY GLY A . n 
A 1 144 SER 144 144 144 SER SER A . n 
A 1 145 CYS 145 145 145 CYS CYS A . n 
A 1 146 GLY 146 146 146 GLY GLY A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 VAL 148 148 148 VAL VAL A . n 
A 1 149 GLY 149 149 149 GLY GLY A . n 
A 1 150 PHE 150 150 150 PHE PHE A . n 
A 1 151 ASN 151 151 151 ASN ASN A . n 
A 1 152 ILE 152 152 152 ILE ILE A . n 
A 1 153 ASP 153 153 153 ASP ASP A . n 
A 1 154 TYR 154 154 154 TYR TYR A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 CYS 156 156 156 CYS CYS A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 PHE 159 159 159 PHE PHE A . n 
A 1 160 CYS 160 160 160 CYS CYS A . n 
A 1 161 TYR 161 161 161 TYR TYR A . n 
A 1 162 MET 162 162 162 MET MET A . n 
A 1 163 HIS 163 163 163 HIS HIS A . n 
A 1 164 HIS 164 164 164 HIS HIS A . n 
A 1 165 MET 165 165 165 MET MET A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 LEU 167 167 167 LEU LEU A . n 
A 1 168 PRO 168 168 168 PRO PRO A . n 
A 1 169 THR 169 169 169 THR THR A . n 
A 1 170 GLY 170 170 170 GLY GLY A . n 
A 1 171 VAL 171 171 171 VAL VAL A . n 
A 1 172 HIS 172 172 172 HIS HIS A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 GLU 178 178 178 GLU GLU A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 ASN 180 180 180 ASN ASN A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 TYR 182 182 182 TYR TYR A . n 
A 1 183 GLY 183 183 183 GLY GLY A . n 
A 1 184 PRO 184 184 184 PRO PRO A . n 
A 1 185 PHE 185 185 185 PHE PHE A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 ASP 187 187 187 ASP ASP A . n 
A 1 188 ARG 188 188 188 ARG ARG A . n 
A 1 189 GLN 189 189 189 GLN GLN A . n 
A 1 190 THR 190 190 190 THR THR A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 GLN 192 192 192 GLN GLN A . n 
A 1 193 ALA 193 193 193 ALA ALA A . n 
A 1 194 ALA 194 194 194 ALA ALA A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 THR 196 196 196 THR THR A . n 
A 1 197 ASP 197 197 197 ASP ASP A . n 
A 1 198 THR 198 198 198 THR THR A . n 
A 1 199 THR 199 199 199 THR THR A . n 
A 1 200 ILE 200 200 200 ILE ILE A . n 
A 1 201 THR 201 201 201 THR THR A . n 
A 1 202 VAL 202 202 202 VAL VAL A . n 
A 1 203 ASN 203 203 203 ASN ASN A . n 
A 1 204 VAL 204 204 204 VAL VAL A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 TRP 207 207 207 TRP TRP A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 TYR 209 209 209 TYR TYR A . n 
A 1 210 ALA 210 210 210 ALA ALA A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ILE 213 213 213 ILE ILE A . n 
A 1 214 ASN 214 214 214 ASN ASN A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 ARG 217 217 217 ARG ARG A . n 
A 1 218 TRP 218 218 218 TRP TRP A . n 
A 1 219 PHE 219 219 219 PHE PHE A . n 
A 1 220 LEU 220 220 220 LEU LEU A . n 
A 1 221 ASN 221 221 221 ASN ASN A . n 
A 1 222 ARG 222 222 222 ARG ARG A . n 
A 1 223 PHE 223 223 223 PHE PHE A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 ASN 228 228 228 ASN ASN A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 ASN 231 231 231 ASN ASN A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 MET 235 235 235 MET MET A . n 
A 1 236 LYS 236 236 236 LYS LYS A . n 
A 1 237 TYR 237 237 237 TYR TYR A . n 
A 1 238 ASN 238 238 238 ASN ASN A . n 
A 1 239 TYR 239 239 239 TYR TYR A . n 
A 1 240 GLU 240 240 240 GLU GLU A . n 
A 1 241 PRO 241 241 241 PRO PRO A . n 
A 1 242 LEU 242 242 242 LEU LEU A . n 
A 1 243 THR 243 243 243 THR THR A . n 
A 1 244 GLN 244 244 244 GLN GLN A . n 
A 1 245 ASP 245 245 245 ASP ASP A . n 
A 1 246 HIS 246 246 246 HIS HIS A . n 
A 1 247 VAL 247 247 247 VAL VAL A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ILE 249 249 249 ILE ILE A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 PRO 252 252 252 PRO PRO A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 GLN 256 256 256 GLN GLN A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLY 258 258 258 GLY GLY A . n 
A 1 259 ILE 259 259 259 ILE ILE A . n 
A 1 260 ALA 260 260 260 ALA ALA A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 ASP 263 263 263 ASP ASP A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 CYS 265 265 265 CYS CYS A . n 
A 1 266 ALA 266 266 266 ALA ALA A . n 
A 1 267 SER 267 267 267 SER SER A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 LYS 269 269 269 LYS LYS A . n 
A 1 270 GLU 270 270 270 GLU GLU A . n 
A 1 271 LEU 271 271 271 LEU LEU A . n 
A 1 272 LEU 272 272 272 LEU LEU A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 ASN 274 274 274 ASN ASN A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 MET 276 276 276 MET MET A . n 
A 1 277 ASN 277 277 277 ASN ASN A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 ARG 279 279 279 ARG ARG A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 ILE 281 281 281 ILE ILE A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 SER 284 284 284 SER SER A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 LEU 286 286 286 LEU LEU A . n 
A 1 287 LEU 287 287 287 LEU LEU A . n 
A 1 288 GLU 288 288 288 GLU GLU A . n 
A 1 289 ASP 289 289 289 ASP ASP A . n 
A 1 290 GLU 290 290 290 GLU GLU A . n 
A 1 291 PHE 291 291 291 PHE PHE A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 PRO 293 293 293 PRO PRO A . n 
A 1 294 PHE 294 294 294 PHE PHE A . n 
A 1 295 ASP 295 295 295 ASP ASP A . n 
A 1 296 VAL 296 296 296 VAL VAL A . n 
A 1 297 VAL 297 297 297 VAL VAL A . n 
A 1 298 ARG 298 298 298 ARG ARG A . n 
A 1 299 GLN 299 299 299 GLN GLN A . n 
A 1 300 CYS 300 300 300 CYS CYS A . n 
A 1 301 SER 301 301 301 SER SER A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 THR 304 304 304 THR THR A . n 
A 1 305 PHE 305 305 305 PHE PHE A . n 
A 1 306 GLN 306 306 ?   ?   ?   A . n 
B 1 1   SER 1   1   1   SER SER B . n 
B 1 2   GLY 2   2   2   GLY GLY B . n 
B 1 3   PHE 3   3   3   PHE PHE B . n 
B 1 4   ARG 4   4   4   ARG ARG B . n 
B 1 5   LYS 5   5   5   LYS LYS B . n 
B 1 6   MET 6   6   6   MET MET B . n 
B 1 7   ALA 7   7   7   ALA ALA B . n 
B 1 8   PHE 8   8   8   PHE PHE B . n 
B 1 9   PRO 9   9   9   PRO PRO B . n 
B 1 10  SER 10  10  10  SER SER B . n 
B 1 11  GLY 11  11  11  GLY GLY B . n 
B 1 12  LYS 12  12  12  LYS LYS B . n 
B 1 13  VAL 13  13  13  VAL VAL B . n 
B 1 14  GLU 14  14  14  GLU GLU B . n 
B 1 15  GLY 15  15  15  GLY GLY B . n 
B 1 16  CYS 16  16  16  CYS CYS B . n 
B 1 17  MET 17  17  17  MET MET B . n 
B 1 18  VAL 18  18  18  VAL VAL B . n 
B 1 19  GLN 19  19  19  GLN GLN B . n 
B 1 20  VAL 20  20  20  VAL VAL B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  CYS 22  22  22  CYS CYS B . n 
B 1 23  GLY 23  23  23  GLY GLY B . n 
B 1 24  THR 24  24  24  THR THR B . n 
B 1 25  THR 25  25  25  THR THR B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  LEU 27  27  27  LEU LEU B . n 
B 1 28  ASN 28  28  28  ASN ASN B . n 
B 1 29  GLY 29  29  29  GLY GLY B . n 
B 1 30  LEU 30  30  30  LEU LEU B . n 
B 1 31  TRP 31  31  31  TRP TRP B . n 
B 1 32  LEU 32  32  32  LEU LEU B . n 
B 1 33  ASP 33  33  33  ASP ASP B . n 
B 1 34  ASP 34  34  34  ASP ASP B . n 
B 1 35  VAL 35  35  35  VAL VAL B . n 
B 1 36  VAL 36  36  36  VAL VAL B . n 
B 1 37  TYR 37  37  37  TYR TYR B . n 
B 1 38  CYS 38  38  38  CYS CYS B . n 
B 1 39  PRO 39  39  39  PRO PRO B . n 
B 1 40  ARG 40  40  40  ARG ARG B . n 
B 1 41  HIS 41  41  41  HIS HIS B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  ILE 43  43  43  ILE ILE B . n 
B 1 44  CYS 44  44  44  CYS CYS B . n 
B 1 45  THR 45  45  45  THR THR B . n 
B 1 46  SER 46  46  46  SER SER B . n 
B 1 47  GLU 47  47  47  GLU GLU B . n 
B 1 48  ASP 48  48  48  ASP ASP B . n 
B 1 49  MET 49  49  49  MET MET B . n 
B 1 50  LEU 50  50  50  LEU LEU B . n 
B 1 51  ASN 51  51  51  ASN ASN B . n 
B 1 52  PRO 52  52  52  PRO PRO B . n 
B 1 53  ASN 53  53  53  ASN ASN B . n 
B 1 54  TYR 54  54  54  TYR TYR B . n 
B 1 55  GLU 55  55  55  GLU GLU B . n 
B 1 56  ASP 56  56  56  ASP ASP B . n 
B 1 57  LEU 57  57  57  LEU LEU B . n 
B 1 58  LEU 58  58  58  LEU LEU B . n 
B 1 59  ILE 59  59  59  ILE ILE B . n 
B 1 60  ARG 60  60  60  ARG ARG B . n 
B 1 61  LYS 61  61  61  LYS LYS B . n 
B 1 62  SER 62  62  62  SER SER B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  HIS 64  64  64  HIS HIS B . n 
B 1 65  ASN 65  65  65  ASN ASN B . n 
B 1 66  PHE 66  66  66  PHE PHE B . n 
B 1 67  LEU 67  67  67  LEU LEU B . n 
B 1 68  VAL 68  68  68  VAL VAL B . n 
B 1 69  GLN 69  69  69  GLN GLN B . n 
B 1 70  ALA 70  70  70  ALA ALA B . n 
B 1 71  GLY 71  71  71  GLY GLY B . n 
B 1 72  ASN 72  72  72  ASN ASN B . n 
B 1 73  VAL 73  73  73  VAL VAL B . n 
B 1 74  GLN 74  74  74  GLN GLN B . n 
B 1 75  LEU 75  75  75  LEU LEU B . n 
B 1 76  ARG 76  76  76  ARG ARG B . n 
B 1 77  VAL 77  77  77  VAL VAL B . n 
B 1 78  ILE 78  78  78  ILE ILE B . n 
B 1 79  GLY 79  79  79  GLY GLY B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  SER 81  81  81  SER SER B . n 
B 1 82  MET 82  82  82  MET MET B . n 
B 1 83  GLN 83  83  83  GLN GLN B . n 
B 1 84  ASN 84  84  84  ASN ASN B . n 
B 1 85  CYS 85  85  85  CYS CYS B . n 
B 1 86  VAL 86  86  86  VAL VAL B . n 
B 1 87  LEU 87  87  87  LEU LEU B . n 
B 1 88  LYS 88  88  88  LYS LYS B . n 
B 1 89  LEU 89  89  89  LEU LEU B . n 
B 1 90  LYS 90  90  90  LYS LYS B . n 
B 1 91  VAL 91  91  91  VAL VAL B . n 
B 1 92  ASP 92  92  92  ASP ASP B . n 
B 1 93  THR 93  93  93  THR THR B . n 
B 1 94  ALA 94  94  94  ALA ALA B . n 
B 1 95  ASN 95  95  95  ASN ASN B . n 
B 1 96  PRO 96  96  96  PRO PRO B . n 
B 1 97  LYS 97  97  97  LYS LYS B . n 
B 1 98  THR 98  98  98  THR THR B . n 
B 1 99  PRO 99  99  99  PRO PRO B . n 
B 1 100 LYS 100 100 100 LYS LYS B . n 
B 1 101 TYR 101 101 101 TYR TYR B . n 
B 1 102 LYS 102 102 102 LYS LYS B . n 
B 1 103 PHE 103 103 103 PHE PHE B . n 
B 1 104 VAL 104 104 104 VAL VAL B . n 
B 1 105 ARG 105 105 105 ARG ARG B . n 
B 1 106 ILE 106 106 106 ILE ILE B . n 
B 1 107 GLN 107 107 107 GLN GLN B . n 
B 1 108 PRO 108 108 108 PRO PRO B . n 
B 1 109 GLY 109 109 109 GLY GLY B . n 
B 1 110 GLN 110 110 110 GLN GLN B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 PHE 112 112 112 PHE PHE B . n 
B 1 113 SER 113 113 113 SER SER B . n 
B 1 114 VAL 114 114 114 VAL VAL B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 ALA 116 116 116 ALA ALA B . n 
B 1 117 CYS 117 117 117 CYS CYS B . n 
B 1 118 TYR 118 118 118 TYR TYR B . n 
B 1 119 ASN 119 119 119 ASN ASN B . n 
B 1 120 GLY 120 120 120 GLY GLY B . n 
B 1 121 SER 121 121 121 SER SER B . n 
B 1 122 PRO 122 122 122 PRO PRO B . n 
B 1 123 SER 123 123 123 SER SER B . n 
B 1 124 GLY 124 124 124 GLY GLY B . n 
B 1 125 VAL 125 125 125 VAL VAL B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 GLN 127 127 127 GLN GLN B . n 
B 1 128 CYS 128 128 128 CYS CYS B . n 
B 1 129 ALA 129 129 129 ALA ALA B . n 
B 1 130 MET 130 130 130 MET MET B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 PRO 132 132 132 PRO PRO B . n 
B 1 133 ASN 133 133 133 ASN ASN B . n 
B 1 134 PHE 134 134 134 PHE PHE B . n 
B 1 135 THR 135 135 135 THR THR B . n 
B 1 136 ILE 136 136 136 ILE ILE B . n 
B 1 137 LYS 137 137 137 LYS LYS B . n 
B 1 138 GLY 138 138 138 GLY GLY B . n 
B 1 139 SER 139 139 139 SER SER B . n 
B 1 140 PHE 140 140 140 PHE PHE B . n 
B 1 141 LEU 141 141 141 LEU LEU B . n 
B 1 142 ASN 142 142 142 ASN ASN B . n 
B 1 143 GLY 143 143 143 GLY GLY B . n 
B 1 144 SER 144 144 144 SER SER B . n 
B 1 145 CYS 145 145 145 CYS CYS B . n 
B 1 146 GLY 146 146 146 GLY GLY B . n 
B 1 147 SER 147 147 147 SER SER B . n 
B 1 148 VAL 148 148 148 VAL VAL B . n 
B 1 149 GLY 149 149 149 GLY GLY B . n 
B 1 150 PHE 150 150 150 PHE PHE B . n 
B 1 151 ASN 151 151 151 ASN ASN B . n 
B 1 152 ILE 152 152 152 ILE ILE B . n 
B 1 153 ASP 153 153 153 ASP ASP B . n 
B 1 154 TYR 154 154 154 TYR TYR B . n 
B 1 155 ASP 155 155 155 ASP ASP B . n 
B 1 156 CYS 156 156 156 CYS CYS B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 SER 158 158 158 SER SER B . n 
B 1 159 PHE 159 159 159 PHE PHE B . n 
B 1 160 CYS 160 160 160 CYS CYS B . n 
B 1 161 TYR 161 161 161 TYR TYR B . n 
B 1 162 MET 162 162 162 MET MET B . n 
B 1 163 HIS 163 163 163 HIS HIS B . n 
B 1 164 HIS 164 164 164 HIS HIS B . n 
B 1 165 MET 165 165 165 MET MET B . n 
B 1 166 GLU 166 166 166 GLU GLU B . n 
B 1 167 LEU 167 167 167 LEU LEU B . n 
B 1 168 PRO 168 168 168 PRO PRO B . n 
B 1 169 THR 169 169 169 THR THR B . n 
B 1 170 GLY 170 170 170 GLY GLY B . n 
B 1 171 VAL 171 171 171 VAL VAL B . n 
B 1 172 HIS 172 172 172 HIS HIS B . n 
B 1 173 ALA 173 173 173 ALA ALA B . n 
B 1 174 GLY 174 174 174 GLY GLY B . n 
B 1 175 THR 175 175 175 THR THR B . n 
B 1 176 ASP 176 176 176 ASP ASP B . n 
B 1 177 LEU 177 177 177 LEU LEU B . n 
B 1 178 GLU 178 178 178 GLU GLU B . n 
B 1 179 GLY 179 179 179 GLY GLY B . n 
B 1 180 ASN 180 180 180 ASN ASN B . n 
B 1 181 PHE 181 181 181 PHE PHE B . n 
B 1 182 TYR 182 182 182 TYR TYR B . n 
B 1 183 GLY 183 183 183 GLY GLY B . n 
B 1 184 PRO 184 184 184 PRO PRO B . n 
B 1 185 PHE 185 185 185 PHE PHE B . n 
B 1 186 VAL 186 186 186 VAL VAL B . n 
B 1 187 ASP 187 187 187 ASP ASP B . n 
B 1 188 ARG 188 188 188 ARG ARG B . n 
B 1 189 GLN 189 189 189 GLN GLN B . n 
B 1 190 THR 190 190 190 THR THR B . n 
B 1 191 ALA 191 191 191 ALA ALA B . n 
B 1 192 GLN 192 192 192 GLN GLN B . n 
B 1 193 ALA 193 193 193 ALA ALA B . n 
B 1 194 ALA 194 194 194 ALA ALA B . n 
B 1 195 GLY 195 195 195 GLY GLY B . n 
B 1 196 THR 196 196 196 THR THR B . n 
B 1 197 ASP 197 197 197 ASP ASP B . n 
B 1 198 THR 198 198 198 THR THR B . n 
B 1 199 THR 199 199 199 THR THR B . n 
B 1 200 ILE 200 200 200 ILE ILE B . n 
B 1 201 THR 201 201 201 THR THR B . n 
B 1 202 VAL 202 202 202 VAL VAL B . n 
B 1 203 ASN 203 203 203 ASN ASN B . n 
B 1 204 VAL 204 204 204 VAL VAL B . n 
B 1 205 LEU 205 205 205 LEU LEU B . n 
B 1 206 ALA 206 206 206 ALA ALA B . n 
B 1 207 TRP 207 207 207 TRP TRP B . n 
B 1 208 LEU 208 208 208 LEU LEU B . n 
B 1 209 TYR 209 209 209 TYR TYR B . n 
B 1 210 ALA 210 210 210 ALA ALA B . n 
B 1 211 ALA 211 211 211 ALA ALA B . n 
B 1 212 VAL 212 212 212 VAL VAL B . n 
B 1 213 ILE 213 213 213 ILE ILE B . n 
B 1 214 ASN 214 214 214 ASN ASN B . n 
B 1 215 GLY 215 215 215 GLY GLY B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 ARG 217 217 217 ARG ARG B . n 
B 1 218 TRP 218 218 218 TRP TRP B . n 
B 1 219 PHE 219 219 219 PHE PHE B . n 
B 1 220 LEU 220 220 220 LEU LEU B . n 
B 1 221 ASN 221 221 221 ASN ASN B . n 
B 1 222 ARG 222 222 222 ARG ARG B . n 
B 1 223 PHE 223 223 223 PHE PHE B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 THR 225 225 225 THR THR B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 LEU 227 227 227 LEU LEU B . n 
B 1 228 ASN 228 228 228 ASN ASN B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 PHE 230 230 230 PHE PHE B . n 
B 1 231 ASN 231 231 231 ASN ASN B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 VAL 233 233 233 VAL VAL B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 MET 235 235 235 MET MET B . n 
B 1 236 LYS 236 236 236 LYS LYS B . n 
B 1 237 TYR 237 237 237 TYR TYR B . n 
B 1 238 ASN 238 238 238 ASN ASN B . n 
B 1 239 TYR 239 239 239 TYR TYR B . n 
B 1 240 GLU 240 240 240 GLU GLU B . n 
B 1 241 PRO 241 241 241 PRO PRO B . n 
B 1 242 LEU 242 242 242 LEU LEU B . n 
B 1 243 THR 243 243 243 THR THR B . n 
B 1 244 GLN 244 244 244 GLN GLN B . n 
B 1 245 ASP 245 245 245 ASP ASP B . n 
B 1 246 HIS 246 246 246 HIS HIS B . n 
B 1 247 VAL 247 247 247 VAL VAL B . n 
B 1 248 ASP 248 248 248 ASP ASP B . n 
B 1 249 ILE 249 249 249 ILE ILE B . n 
B 1 250 LEU 250 250 250 LEU LEU B . n 
B 1 251 GLY 251 251 251 GLY GLY B . n 
B 1 252 PRO 252 252 252 PRO PRO B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 GLN 256 256 256 GLN GLN B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLY 258 258 258 GLY GLY B . n 
B 1 259 ILE 259 259 259 ILE ILE B . n 
B 1 260 ALA 260 260 260 ALA ALA B . n 
B 1 261 VAL 261 261 261 VAL VAL B . n 
B 1 262 LEU 262 262 262 LEU LEU B . n 
B 1 263 ASP 263 263 263 ASP ASP B . n 
B 1 264 MET 264 264 264 MET MET B . n 
B 1 265 CYS 265 265 265 CYS CYS B . n 
B 1 266 ALA 266 266 266 ALA ALA B . n 
B 1 267 SER 267 267 267 SER SER B . n 
B 1 268 LEU 268 268 268 LEU LEU B . n 
B 1 269 LYS 269 269 269 LYS LYS B . n 
B 1 270 GLU 270 270 270 GLU GLU B . n 
B 1 271 LEU 271 271 271 LEU LEU B . n 
B 1 272 LEU 272 272 272 LEU LEU B . n 
B 1 273 GLN 273 273 273 GLN GLN B . n 
B 1 274 ASN 274 274 274 ASN ASN B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 MET 276 276 276 MET MET B . n 
B 1 277 ASN 277 277 277 ASN ASN B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 ARG 279 279 279 ARG ARG B . n 
B 1 280 THR 280 280 280 THR THR B . n 
B 1 281 ILE 281 281 281 ILE ILE B . n 
B 1 282 LEU 282 282 282 LEU LEU B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 SER 284 284 284 SER SER B . n 
B 1 285 ALA 285 285 285 ALA ALA B . n 
B 1 286 LEU 286 286 286 LEU LEU B . n 
B 1 287 LEU 287 287 287 LEU LEU B . n 
B 1 288 GLU 288 288 288 GLU GLU B . n 
B 1 289 ASP 289 289 289 ASP ASP B . n 
B 1 290 GLU 290 290 290 GLU GLU B . n 
B 1 291 PHE 291 291 291 PHE PHE B . n 
B 1 292 THR 292 292 292 THR THR B . n 
B 1 293 PRO 293 293 293 PRO PRO B . n 
B 1 294 PHE 294 294 294 PHE PHE B . n 
B 1 295 ASP 295 295 295 ASP ASP B . n 
B 1 296 VAL 296 296 296 VAL VAL B . n 
B 1 297 VAL 297 297 297 VAL VAL B . n 
B 1 298 ARG 298 298 298 ARG ARG B . n 
B 1 299 GLN 299 299 299 GLN GLN B . n 
B 1 300 CYS 300 300 300 CYS CYS B . n 
B 1 301 SER 301 301 301 SER SER B . n 
B 1 302 GLY 302 302 302 GLY GLY B . n 
B 1 303 VAL 303 303 303 VAL VAL B . n 
B 1 304 THR 304 304 ?   ?   ?   B . n 
B 1 305 PHE 305 305 ?   ?   ?   B . n 
B 1 306 GLN 306 306 ?   ?   ?   B . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 4WI ? ? 4WI ? ? 'SUBJECT OF INVESTIGATION' ? 
2 4WI ? ? 4WI ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 4WI 1  401 999 4WI NMA A . 
D 2 4WI 1  401 999 4WI NMB B . 
E 3 HOH 1  501 9   HOH HOH A . 
E 3 HOH 2  502 32  HOH HOH A . 
E 3 HOH 3  503 58  HOH HOH A . 
E 3 HOH 4  504 24  HOH HOH A . 
E 3 HOH 5  505 35  HOH HOH A . 
E 3 HOH 6  506 43  HOH HOH A . 
E 3 HOH 7  507 10  HOH HOH A . 
E 3 HOH 8  508 11  HOH HOH A . 
E 3 HOH 9  509 28  HOH HOH A . 
E 3 HOH 10 510 23  HOH HOH A . 
E 3 HOH 11 511 34  HOH HOH A . 
E 3 HOH 12 512 6   HOH HOH A . 
E 3 HOH 13 513 22  HOH HOH A . 
E 3 HOH 14 514 14  HOH HOH A . 
E 3 HOH 15 515 47  HOH HOH A . 
E 3 HOH 16 516 48  HOH HOH A . 
E 3 HOH 17 517 26  HOH HOH A . 
E 3 HOH 18 518 19  HOH HOH A . 
E 3 HOH 19 519 40  HOH HOH A . 
E 3 HOH 20 520 46  HOH HOH A . 
E 3 HOH 21 521 54  HOH HOH A . 
E 3 HOH 22 522 44  HOH HOH A . 
E 3 HOH 23 523 21  HOH HOH A . 
E 3 HOH 24 524 37  HOH HOH A . 
E 3 HOH 25 525 38  HOH HOH A . 
F 3 HOH 1  501 4   HOH HOH B . 
F 3 HOH 2  502 8   HOH HOH B . 
F 3 HOH 3  503 7   HOH HOH B . 
F 3 HOH 4  504 49  HOH HOH B . 
F 3 HOH 5  505 29  HOH HOH B . 
F 3 HOH 6  506 1   HOH HOH B . 
F 3 HOH 7  507 25  HOH HOH B . 
F 3 HOH 8  508 36  HOH HOH B . 
F 3 HOH 9  509 20  HOH HOH B . 
F 3 HOH 10 510 39  HOH HOH B . 
F 3 HOH 11 511 13  HOH HOH B . 
F 3 HOH 12 512 18  HOH HOH B . 
F 3 HOH 13 513 50  HOH HOH B . 
F 3 HOH 14 514 16  HOH HOH B . 
F 3 HOH 15 515 5   HOH HOH B . 
F 3 HOH 16 516 57  HOH HOH B . 
F 3 HOH 17 517 52  HOH HOH B . 
F 3 HOH 18 518 3   HOH HOH B . 
F 3 HOH 19 519 2   HOH HOH B . 
F 3 HOH 20 520 41  HOH HOH B . 
F 3 HOH 21 521 56  HOH HOH B . 
F 3 HOH 22 522 27  HOH HOH B . 
F 3 HOH 23 523 31  HOH HOH B . 
F 3 HOH 24 524 15  HOH HOH B . 
F 3 HOH 25 525 51  HOH HOH B . 
F 3 HOH 26 526 30  HOH HOH B . 
F 3 HOH 27 527 12  HOH HOH B . 
F 3 HOH 28 528 55  HOH HOH B . 
F 3 HOH 29 529 33  HOH HOH B . 
F 3 HOH 30 530 53  HOH HOH B . 
F 3 HOH 31 531 59  HOH HOH B . 
F 3 HOH 32 532 42  HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A ARG 60  ? CG  ? A ARG 60  CG  
2  1 Y 1 A ARG 60  ? CD  ? A ARG 60  CD  
3  1 Y 1 A ARG 60  ? NE  ? A ARG 60  NE  
4  1 Y 1 A ARG 60  ? CZ  ? A ARG 60  CZ  
5  1 Y 1 A ARG 60  ? NH1 ? A ARG 60  NH1 
6  1 Y 1 A ARG 60  ? NH2 ? A ARG 60  NH2 
7  1 Y 1 A ASN 72  ? CG  ? A ASN 72  CG  
8  1 Y 1 A ASN 72  ? OD1 ? A ASN 72  OD1 
9  1 Y 1 A ASN 72  ? ND2 ? A ASN 72  ND2 
10 1 Y 1 A ARG 217 ? CG  ? A ARG 217 CG  
11 1 Y 1 A ARG 217 ? CD  ? A ARG 217 CD  
12 1 Y 1 A ARG 217 ? NE  ? A ARG 217 NE  
13 1 Y 1 A ARG 217 ? CZ  ? A ARG 217 CZ  
14 1 Y 1 A ARG 217 ? NH1 ? A ARG 217 NH1 
15 1 Y 1 A ARG 217 ? NH2 ? A ARG 217 NH2 
16 1 Y 1 A ARG 222 ? CG  ? A ARG 222 CG  
17 1 Y 1 A ARG 222 ? CD  ? A ARG 222 CD  
18 1 Y 1 A ARG 222 ? NE  ? A ARG 222 NE  
19 1 Y 1 A ARG 222 ? CZ  ? A ARG 222 CZ  
20 1 Y 1 A ARG 222 ? NH1 ? A ARG 222 NH1 
21 1 Y 1 A ARG 222 ? NH2 ? A ARG 222 NH2 
22 1 Y 1 A LYS 236 ? CG  ? A LYS 236 CG  
23 1 Y 1 A LYS 236 ? CD  ? A LYS 236 CD  
24 1 Y 1 A LYS 236 ? CE  ? A LYS 236 CE  
25 1 Y 1 A LYS 236 ? NZ  ? A LYS 236 NZ  
26 1 Y 1 A LYS 269 ? CG  ? A LYS 269 CG  
27 1 Y 1 A LYS 269 ? CD  ? A LYS 269 CD  
28 1 Y 1 A LYS 269 ? CE  ? A LYS 269 CE  
29 1 Y 1 A LYS 269 ? NZ  ? A LYS 269 NZ  
30 1 Y 1 B SER 46  ? OG  ? B SER 46  OG  
31 1 Y 1 B LEU 67  ? CG  ? B LEU 67  CG  
32 1 Y 1 B LEU 67  ? CD1 ? B LEU 67  CD1 
33 1 Y 1 B LEU 67  ? CD2 ? B LEU 67  CD2 
34 1 Y 1 B GLN 74  ? CG  ? B GLN 74  CG  
35 1 Y 1 B GLN 74  ? CD  ? B GLN 74  CD  
36 1 Y 1 B GLN 74  ? OE1 ? B GLN 74  OE1 
37 1 Y 1 B GLN 74  ? NE2 ? B GLN 74  NE2 
38 1 Y 1 B ARG 222 ? CG  ? B ARG 222 CG  
39 1 Y 1 B ARG 222 ? CD  ? B ARG 222 CD  
40 1 Y 1 B ARG 222 ? NE  ? B ARG 222 NE  
41 1 Y 1 B ARG 222 ? CZ  ? B ARG 222 CZ  
42 1 Y 1 B ARG 222 ? NH1 ? B ARG 222 NH1 
43 1 Y 1 B ARG 222 ? NH2 ? B ARG 222 NH2 
44 1 Y 1 B LEU 232 ? CG  ? B LEU 232 CG  
45 1 Y 1 B LEU 232 ? CD1 ? B LEU 232 CD1 
46 1 Y 1 B LEU 232 ? CD2 ? B LEU 232 CD2 
47 1 Y 1 B LYS 236 ? CG  ? B LYS 236 CG  
48 1 Y 1 B LYS 236 ? CD  ? B LYS 236 CD  
49 1 Y 1 B LYS 236 ? CE  ? B LYS 236 CE  
50 1 Y 1 B LYS 236 ? NZ  ? B LYS 236 NZ  
51 1 Y 1 B LYS 269 ? CG  ? B LYS 269 CG  
52 1 Y 1 B LYS 269 ? CD  ? B LYS 269 CD  
53 1 Y 1 B LYS 269 ? CE  ? B LYS 269 CE  
54 1 Y 1 B LYS 269 ? NZ  ? B LYS 269 NZ  
55 1 Y 1 B ASN 277 ? CG  ? B ASN 277 CG  
56 1 Y 1 B ASN 277 ? OD1 ? B ASN 277 OD1 
57 1 Y 1 B ASN 277 ? ND2 ? B ASN 277 ND2 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.19.2_4158 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .           2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .           3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? .           4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   100.540 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BO4 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     45.640 
_cell.length_a_esd                 ? 
_cell.length_b                     53.700 
_cell.length_b_esd                 ? 
_cell.length_c                     114.410 
_cell.length_c_esd                 ? 
_cell.volume                       275672.679 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BO4 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BO4 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.04 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          39.61 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.0 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    '20% v/v 2-Propanol, 0.1 M MES monohydrate, 20% w/v Polyethylene glycol monomethyl ether 2,000' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            294 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 9M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-06-07 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.920105 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'NSLS-II BEAMLINE 17-ID-1' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.920105 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   17-ID-1 
_diffrn_source.pdbx_synchrotron_site       NSLS-II 
# 
_reflns.B_iso_Wilson_estimate                          41.68 
_reflns.entry_id                                       9BO4 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.28 
_reflns.d_resolution_low                               39.28 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     24919 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           98.69 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                6.9 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          8.56 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   0.997 
_reflns.pdbx_CC_star                                   0.999 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.1572 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.28 
_reflns_shell.d_res_low                                     2.361 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           1.18 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             2444 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               7.1 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.46 
_reflns_shell.pdbx_CC_star                                  0.794 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          99.11 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  1.724 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               46.46 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BO4 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.28 
_refine.ls_d_res_low                             39.28 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     24919 
_refine.ls_number_reflns_R_free                  1159 
_refine.ls_number_reflns_R_work                  23760 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    98.69 
_refine.ls_percent_reflns_R_free                 4.65 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1967 
_refine.ls_R_factor_R_free                       0.2523 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1941 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1100 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 28.1306 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.3223 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.28 
_refine_hist.d_res_low                        39.28 
_refine_hist.number_atoms_solvent             57 
_refine_hist.number_atoms_total               4770 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4643 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         70 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0031  ? 4844 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.6713  ? 6618 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0427  ? 747  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0046  ? 854  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 13.4168 ? 1699 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.28 2.38  . . 143 2930 98.56 . . . . 0.2862 . . . . . . . . . . . 0.3573 
'X-RAY DIFFRACTION' 2.38 2.51  . . 179 2886 98.49 . . . . 0.2666 . . . . . . . . . . . 0.3367 
'X-RAY DIFFRACTION' 2.51 2.66  . . 178 2935 98.61 . . . . 0.2367 . . . . . . . . . . . 0.3199 
'X-RAY DIFFRACTION' 2.66 2.87  . . 138 2948 98.16 . . . . 0.2320 . . . . . . . . . . . 0.3086 
'X-RAY DIFFRACTION' 2.87 3.16  . . 106 3001 99.23 . . . . 0.1941 . . . . . . . . . . . 0.2679 
'X-RAY DIFFRACTION' 3.16 3.61  . . 137 2978 98.83 . . . . 0.1937 . . . . . . . . . . . 0.2749 
'X-RAY DIFFRACTION' 3.61 4.55  . . 143 3017 99.25 . . . . 0.1594 . . . . . . . . . . . 0.2112 
'X-RAY DIFFRACTION' 4.55 39.28 . . 135 3065 98.37 . . . . 0.1764 . . . . . . . . . . . 0.2010 
# 
_struct.entry_id                     9BO4 
_struct.title                        'Crystal Structure of T21I SARS-CoV-2 Main Protease in Complex with Nirmatrelvir' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BO4 
_struct_keywords.text            'Hydrolase, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    R1A_SARS2 
_struct_ref.pdbx_db_accession          P0DTC1 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
_struct_ref.pdbx_align_begin           3264 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BO4 A 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
2 1 9BO4 B 1 ? 306 ? P0DTC1 3264 ? 3569 ? 1 306 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BO4 ILE A 21 ? UNP P0DTC1 THR 3284 'engineered mutation' 21 1 
2 9BO4 ILE B 21 ? UNP P0DTC1 THR 3284 'engineered mutation' 21 2 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 2930  ? 
1 MORE         -12   ? 
1 'SSA (A^2)'  24530 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 15  ? SER A 10  GLY A 15  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 41  ? CYS A 44  ? HIS A 41  CYS A 44  5 ? 4  
HELX_P HELX_P3  AA3 GLU A 47  ? ASN A 51  ? GLU A 47  ASN A 51  5 ? 5  
HELX_P HELX_P4  AA4 ASN A 53  ? ARG A 60  ? ASN A 53  ARG A 60  1 ? 8  
HELX_P HELX_P5  AA5 SER A 62  ? HIS A 64  ? SER A 62  HIS A 64  5 ? 3  
HELX_P HELX_P6  AA6 PRO A 168 ? GLY A 170 ? PRO A 168 GLY A 170 5 ? 3  
HELX_P HELX_P7  AA7 ILE A 200 ? ASN A 214 ? ILE A 200 ASN A 214 1 ? 15 
HELX_P HELX_P8  AA8 THR A 226 ? TYR A 237 ? THR A 226 TYR A 237 1 ? 12 
HELX_P HELX_P9  AA9 THR A 243 ? LEU A 250 ? THR A 243 LEU A 250 1 ? 8  
HELX_P HELX_P10 AB1 LEU A 250 ? GLY A 258 ? LEU A 250 GLY A 258 1 ? 9  
HELX_P HELX_P11 AB2 ALA A 260 ? GLY A 275 ? ALA A 260 GLY A 275 1 ? 16 
HELX_P HELX_P12 AB3 THR A 292 ? GLY A 302 ? THR A 292 GLY A 302 1 ? 11 
HELX_P HELX_P13 AB4 SER B 10  ? GLY B 15  ? SER B 10  GLY B 15  1 ? 6  
HELX_P HELX_P14 AB5 HIS B 41  ? CYS B 44  ? HIS B 41  CYS B 44  5 ? 4  
HELX_P HELX_P15 AB6 GLU B 47  ? ASN B 51  ? GLU B 47  ASN B 51  5 ? 5  
HELX_P HELX_P16 AB7 ASN B 53  ? ARG B 60  ? ASN B 53  ARG B 60  1 ? 8  
HELX_P HELX_P17 AB8 SER B 62  ? HIS B 64  ? SER B 62  HIS B 64  5 ? 3  
HELX_P HELX_P18 AB9 ILE B 200 ? ASN B 214 ? ILE B 200 ASN B 214 1 ? 15 
HELX_P HELX_P19 AC1 THR B 226 ? TYR B 237 ? THR B 226 TYR B 237 1 ? 12 
HELX_P HELX_P20 AC2 THR B 243 ? LEU B 250 ? THR B 243 LEU B 250 1 ? 8  
HELX_P HELX_P21 AC3 LEU B 250 ? GLY B 258 ? LEU B 250 GLY B 258 1 ? 9  
HELX_P HELX_P22 AC4 ALA B 260 ? GLY B 275 ? ALA B 260 GLY B 275 1 ? 16 
HELX_P HELX_P23 AC5 THR B 292 ? GLY B 302 ? THR B 292 GLY B 302 1 ? 11 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? A CYS 145 SG ? ? ? 1_555 C 4WI . C3 ? ? A CYS 145 A 4WI 401 1_555 ? ? ? ? ? ? ? 1.766 ? ? 
covale2 covale none ? B CYS 145 SG ? ? ? 1_555 D 4WI . C3 ? ? B CYS 145 B 4WI 401 1_555 ? ? ? ? ? ? ? 1.766 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 4WI C . ? CYS A 145 ? 4WI A 401 ? 1_555 CYS A 145 ? 1_555 C3 SG CYS 1 4WI None 'Covalent chemical modification' 
2 4WI D . ? CYS B 145 ? 4WI B 401 ? 1_555 CYS B 145 ? 1_555 C3 SG CYS 1 4WI None 'Covalent chemical modification' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 73  ? LEU A 75  ? VAL A 73  LEU A 75  
AA1 2 PHE A 66  ? ALA A 70  ? PHE A 66  ALA A 70  
AA1 3 MET A 17  ? CYS A 22  ? MET A 17  CYS A 22  
AA1 4 THR A 25  ? LEU A 32  ? THR A 25  LEU A 32  
AA1 5 VAL A 35  ? PRO A 39  ? VAL A 35  PRO A 39  
AA1 6 VAL A 86  ? VAL A 91  ? VAL A 86  VAL A 91  
AA1 7 VAL A 77  ? GLN A 83  ? VAL A 77  GLN A 83  
AA2 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA2 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA2 3 VAL A 148 ? ASP A 153 ? VAL A 148 ASP A 153 
AA2 4 THR A 111 ? TYR A 118 ? THR A 111 TYR A 118 
AA2 5 SER A 121 ? ALA A 129 ? SER A 121 ALA A 129 
AA3 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA3 2 CYS A 156 ? LEU A 167 ? CYS A 156 LEU A 167 
AA3 3 VAL A 171 ? THR A 175 ? VAL A 171 THR A 175 
AA4 1 VAL B 73  ? LEU B 75  ? VAL B 73  LEU B 75  
AA4 2 PHE B 66  ? ALA B 70  ? PHE B 66  ALA B 70  
AA4 3 MET B 17  ? CYS B 22  ? MET B 17  CYS B 22  
AA4 4 THR B 25  ? LEU B 32  ? THR B 25  LEU B 32  
AA4 5 VAL B 35  ? PRO B 39  ? VAL B 35  PRO B 39  
AA4 6 VAL B 86  ? VAL B 91  ? VAL B 86  VAL B 91  
AA4 7 VAL B 77  ? GLN B 83  ? VAL B 77  GLN B 83  
AA5 1 TYR B 101 ? PHE B 103 ? TYR B 101 PHE B 103 
AA5 2 CYS B 156 ? GLU B 166 ? CYS B 156 GLU B 166 
AA5 3 VAL B 148 ? ASP B 153 ? VAL B 148 ASP B 153 
AA5 4 THR B 111 ? TYR B 118 ? THR B 111 TYR B 118 
AA5 5 SER B 121 ? ALA B 129 ? SER B 121 ALA B 129 
AA6 1 TYR B 101 ? PHE B 103 ? TYR B 101 PHE B 103 
AA6 2 CYS B 156 ? GLU B 166 ? CYS B 156 GLU B 166 
AA6 3 HIS B 172 ? THR B 175 ? HIS B 172 THR B 175 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 75  ? O LEU A 75  N VAL A 68  ? N VAL A 68  
AA1 2 3 O LEU A 67  ? O LEU A 67  N ILE A 21  ? N ILE A 21  
AA1 3 4 N VAL A 20  ? N VAL A 20  O LEU A 27  ? O LEU A 27  
AA1 4 5 N LEU A 30  ? N LEU A 30  O TYR A 37  ? O TYR A 37  
AA1 5 6 N CYS A 38  ? N CYS A 38  O LEU A 87  ? O LEU A 87  
AA1 6 7 O LYS A 88  ? O LYS A 88  N SER A 81  ? N SER A 81  
AA2 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA2 2 3 O SER A 158 ? O SER A 158 N ASN A 151 ? N ASN A 151 
AA2 3 4 O PHE A 150 ? O PHE A 150 N SER A 113 ? N SER A 113 
AA2 4 5 N ALA A 116 ? N ALA A 116 O SER A 123 ? O SER A 123 
AA3 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA3 2 3 N LEU A 167 ? N LEU A 167 O VAL A 171 ? O VAL A 171 
AA4 1 2 O LEU B 75  ? O LEU B 75  N VAL B 68  ? N VAL B 68  
AA4 2 3 O LEU B 67  ? O LEU B 67  N ILE B 21  ? N ILE B 21  
AA4 3 4 N VAL B 20  ? N VAL B 20  O LEU B 27  ? O LEU B 27  
AA4 4 5 N LEU B 30  ? N LEU B 30  O TYR B 37  ? O TYR B 37  
AA4 5 6 N CYS B 38  ? N CYS B 38  O LEU B 87  ? O LEU B 87  
AA4 6 7 O LYS B 88  ? O LYS B 88  N SER B 81  ? N SER B 81  
AA5 1 2 N LYS B 102 ? N LYS B 102 O PHE B 159 ? O PHE B 159 
AA5 2 3 O CYS B 156 ? O CYS B 156 N ASP B 153 ? N ASP B 153 
AA5 3 4 O PHE B 150 ? O PHE B 150 N SER B 113 ? N SER B 113 
AA5 4 5 N ALA B 116 ? N ALA B 116 O SER B 123 ? O SER B 123 
AA6 1 2 N LYS B 102 ? N LYS B 102 O PHE B 159 ? O PHE B 159 
AA6 2 3 N MET B 165 ? N MET B 165 O ALA B 173 ? O ALA B 173 
# 
_pdbx_entry_details.entry_id                   9BO4 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 33  ? ? 58.66   -136.52 
2  1 ASN A 51  ? ? -169.08 76.31   
3  1 ALA A 70  ? ? -111.35 78.51   
4  1 ASN A 84  ? ? 51.04   -119.21 
5  1 TYR A 154 ? ? 55.59   -79.95  
6  1 HIS A 164 ? ? -131.16 -48.56  
7  1 ASP B 33  ? ? 47.88   -137.11 
8  1 ASP B 34  ? ? -95.87  35.33   
9  1 ASN B 51  ? ? -161.57 80.61   
10 1 ASN B 84  ? ? 52.80   -116.24 
11 1 TYR B 154 ? ? 58.21   -84.67  
12 1 PRO B 184 ? ? -95.58  41.09   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A GLN 306 ? A GLN 306 
2 1 Y 1 B THR 304 ? B THR 304 
3 1 Y 1 B PHE 305 ? B PHE 305 
4 1 Y 1 B GLN 306 ? B GLN 306 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
4WI C8   C N N 1   
4WI C3   C N N 2   
4WI C1   C N N 3   
4WI C13  C N N 4   
4WI C21  C N N 5   
4WI C6   C N N 6   
4WI C7   C N N 7   
4WI C10  C N N 8   
4WI C5   C N S 9   
4WI C9   C N S 10  
4WI C11  C N S 11  
4WI C12  C N R 12  
4WI C18  C N N 13  
4WI C19  C N N 14  
4WI C20  C N N 15  
4WI C16  C N N 16  
4WI C17  C N N 17  
4WI C23  C N N 18  
4WI C4   C N N 19  
4WI C2   C N S 20  
4WI C14  C N S 21  
4WI C22  C N N 22  
4WI C15  C N N 23  
4WI N5   N N N 24  
4WI N2   N N N 25  
4WI N3   N N N 26  
4WI N1   N N N 27  
4WI N4   N N N 28  
4WI O1   O N N 29  
4WI O2   O N N 30  
4WI O3   O N N 31  
4WI O4   O N N 32  
4WI F1   F N N 33  
4WI F2   F N N 34  
4WI F3   F N N 35  
4WI H33  H N N 36  
4WI H5   H N N 37  
4WI H6   H N N 38  
4WI H7   H N N 39  
4WI H8   H N N 40  
4WI H11  H N N 41  
4WI H12  H N N 42  
4WI H4   H N N 43  
4WI H10  H N N 44  
4WI H13  H N N 45  
4WI H14  H N N 46  
4WI H23  H N N 47  
4WI H24  H N N 48  
4WI H25  H N N 49  
4WI H26  H N N 50  
4WI H27  H N N 51  
4WI H28  H N N 52  
4WI H17  H N N 53  
4WI H19  H N N 54  
4WI H18  H N N 55  
4WI H20  H N N 56  
4WI H21  H N N 57  
4WI H22  H N N 58  
4WI H29  H N N 59  
4WI H30  H N N 60  
4WI H31  H N N 61  
4WI H2   H N N 62  
4WI H3   H N N 63  
4WI H32  H N N 64  
4WI H15  H N N 65  
4WI H36  H N N 66  
4WI H9   H N N 67  
4WI H1   H N N 68  
4WI H16  H N N 69  
ALA N    N N N 70  
ALA CA   C N S 71  
ALA C    C N N 72  
ALA O    O N N 73  
ALA CB   C N N 74  
ALA OXT  O N N 75  
ALA H    H N N 76  
ALA H2   H N N 77  
ALA HA   H N N 78  
ALA HB1  H N N 79  
ALA HB2  H N N 80  
ALA HB3  H N N 81  
ALA HXT  H N N 82  
ARG N    N N N 83  
ARG CA   C N S 84  
ARG C    C N N 85  
ARG O    O N N 86  
ARG CB   C N N 87  
ARG CG   C N N 88  
ARG CD   C N N 89  
ARG NE   N N N 90  
ARG CZ   C N N 91  
ARG NH1  N N N 92  
ARG NH2  N N N 93  
ARG OXT  O N N 94  
ARG H    H N N 95  
ARG H2   H N N 96  
ARG HA   H N N 97  
ARG HB2  H N N 98  
ARG HB3  H N N 99  
ARG HG2  H N N 100 
ARG HG3  H N N 101 
ARG HD2  H N N 102 
ARG HD3  H N N 103 
ARG HE   H N N 104 
ARG HH11 H N N 105 
ARG HH12 H N N 106 
ARG HH21 H N N 107 
ARG HH22 H N N 108 
ARG HXT  H N N 109 
ASN N    N N N 110 
ASN CA   C N S 111 
ASN C    C N N 112 
ASN O    O N N 113 
ASN CB   C N N 114 
ASN CG   C N N 115 
ASN OD1  O N N 116 
ASN ND2  N N N 117 
ASN OXT  O N N 118 
ASN H    H N N 119 
ASN H2   H N N 120 
ASN HA   H N N 121 
ASN HB2  H N N 122 
ASN HB3  H N N 123 
ASN HD21 H N N 124 
ASN HD22 H N N 125 
ASN HXT  H N N 126 
ASP N    N N N 127 
ASP CA   C N S 128 
ASP C    C N N 129 
ASP O    O N N 130 
ASP CB   C N N 131 
ASP CG   C N N 132 
ASP OD1  O N N 133 
ASP OD2  O N N 134 
ASP OXT  O N N 135 
ASP H    H N N 136 
ASP H2   H N N 137 
ASP HA   H N N 138 
ASP HB2  H N N 139 
ASP HB3  H N N 140 
ASP HD2  H N N 141 
ASP HXT  H N N 142 
CYS N    N N N 143 
CYS CA   C N R 144 
CYS C    C N N 145 
CYS O    O N N 146 
CYS CB   C N N 147 
CYS SG   S N N 148 
CYS OXT  O N N 149 
CYS H    H N N 150 
CYS H2   H N N 151 
CYS HA   H N N 152 
CYS HB2  H N N 153 
CYS HB3  H N N 154 
CYS HG   H N N 155 
CYS HXT  H N N 156 
GLN N    N N N 157 
GLN CA   C N S 158 
GLN C    C N N 159 
GLN O    O N N 160 
GLN CB   C N N 161 
GLN CG   C N N 162 
GLN CD   C N N 163 
GLN OE1  O N N 164 
GLN NE2  N N N 165 
GLN OXT  O N N 166 
GLN H    H N N 167 
GLN H2   H N N 168 
GLN HA   H N N 169 
GLN HB2  H N N 170 
GLN HB3  H N N 171 
GLN HG2  H N N 172 
GLN HG3  H N N 173 
GLN HE21 H N N 174 
GLN HE22 H N N 175 
GLN HXT  H N N 176 
GLU N    N N N 177 
GLU CA   C N S 178 
GLU C    C N N 179 
GLU O    O N N 180 
GLU CB   C N N 181 
GLU CG   C N N 182 
GLU CD   C N N 183 
GLU OE1  O N N 184 
GLU OE2  O N N 185 
GLU OXT  O N N 186 
GLU H    H N N 187 
GLU H2   H N N 188 
GLU HA   H N N 189 
GLU HB2  H N N 190 
GLU HB3  H N N 191 
GLU HG2  H N N 192 
GLU HG3  H N N 193 
GLU HE2  H N N 194 
GLU HXT  H N N 195 
GLY N    N N N 196 
GLY CA   C N N 197 
GLY C    C N N 198 
GLY O    O N N 199 
GLY OXT  O N N 200 
GLY H    H N N 201 
GLY H2   H N N 202 
GLY HA2  H N N 203 
GLY HA3  H N N 204 
GLY HXT  H N N 205 
HIS N    N N N 206 
HIS CA   C N S 207 
HIS C    C N N 208 
HIS O    O N N 209 
HIS CB   C N N 210 
HIS CG   C Y N 211 
HIS ND1  N Y N 212 
HIS CD2  C Y N 213 
HIS CE1  C Y N 214 
HIS NE2  N Y N 215 
HIS OXT  O N N 216 
HIS H    H N N 217 
HIS H2   H N N 218 
HIS HA   H N N 219 
HIS HB2  H N N 220 
HIS HB3  H N N 221 
HIS HD1  H N N 222 
HIS HD2  H N N 223 
HIS HE1  H N N 224 
HIS HE2  H N N 225 
HIS HXT  H N N 226 
HOH O    O N N 227 
HOH H1   H N N 228 
HOH H2   H N N 229 
ILE N    N N N 230 
ILE CA   C N S 231 
ILE C    C N N 232 
ILE O    O N N 233 
ILE CB   C N S 234 
ILE CG1  C N N 235 
ILE CG2  C N N 236 
ILE CD1  C N N 237 
ILE OXT  O N N 238 
ILE H    H N N 239 
ILE H2   H N N 240 
ILE HA   H N N 241 
ILE HB   H N N 242 
ILE HG12 H N N 243 
ILE HG13 H N N 244 
ILE HG21 H N N 245 
ILE HG22 H N N 246 
ILE HG23 H N N 247 
ILE HD11 H N N 248 
ILE HD12 H N N 249 
ILE HD13 H N N 250 
ILE HXT  H N N 251 
LEU N    N N N 252 
LEU CA   C N S 253 
LEU C    C N N 254 
LEU O    O N N 255 
LEU CB   C N N 256 
LEU CG   C N N 257 
LEU CD1  C N N 258 
LEU CD2  C N N 259 
LEU OXT  O N N 260 
LEU H    H N N 261 
LEU H2   H N N 262 
LEU HA   H N N 263 
LEU HB2  H N N 264 
LEU HB3  H N N 265 
LEU HG   H N N 266 
LEU HD11 H N N 267 
LEU HD12 H N N 268 
LEU HD13 H N N 269 
LEU HD21 H N N 270 
LEU HD22 H N N 271 
LEU HD23 H N N 272 
LEU HXT  H N N 273 
LYS N    N N N 274 
LYS CA   C N S 275 
LYS C    C N N 276 
LYS O    O N N 277 
LYS CB   C N N 278 
LYS CG   C N N 279 
LYS CD   C N N 280 
LYS CE   C N N 281 
LYS NZ   N N N 282 
LYS OXT  O N N 283 
LYS H    H N N 284 
LYS H2   H N N 285 
LYS HA   H N N 286 
LYS HB2  H N N 287 
LYS HB3  H N N 288 
LYS HG2  H N N 289 
LYS HG3  H N N 290 
LYS HD2  H N N 291 
LYS HD3  H N N 292 
LYS HE2  H N N 293 
LYS HE3  H N N 294 
LYS HZ1  H N N 295 
LYS HZ2  H N N 296 
LYS HZ3  H N N 297 
LYS HXT  H N N 298 
MET N    N N N 299 
MET CA   C N S 300 
MET C    C N N 301 
MET O    O N N 302 
MET CB   C N N 303 
MET CG   C N N 304 
MET SD   S N N 305 
MET CE   C N N 306 
MET OXT  O N N 307 
MET H    H N N 308 
MET H2   H N N 309 
MET HA   H N N 310 
MET HB2  H N N 311 
MET HB3  H N N 312 
MET HG2  H N N 313 
MET HG3  H N N 314 
MET HE1  H N N 315 
MET HE2  H N N 316 
MET HE3  H N N 317 
MET HXT  H N N 318 
PHE N    N N N 319 
PHE CA   C N S 320 
PHE C    C N N 321 
PHE O    O N N 322 
PHE CB   C N N 323 
PHE CG   C Y N 324 
PHE CD1  C Y N 325 
PHE CD2  C Y N 326 
PHE CE1  C Y N 327 
PHE CE2  C Y N 328 
PHE CZ   C Y N 329 
PHE OXT  O N N 330 
PHE H    H N N 331 
PHE H2   H N N 332 
PHE HA   H N N 333 
PHE HB2  H N N 334 
PHE HB3  H N N 335 
PHE HD1  H N N 336 
PHE HD2  H N N 337 
PHE HE1  H N N 338 
PHE HE2  H N N 339 
PHE HZ   H N N 340 
PHE HXT  H N N 341 
PRO N    N N N 342 
PRO CA   C N S 343 
PRO C    C N N 344 
PRO O    O N N 345 
PRO CB   C N N 346 
PRO CG   C N N 347 
PRO CD   C N N 348 
PRO OXT  O N N 349 
PRO H    H N N 350 
PRO HA   H N N 351 
PRO HB2  H N N 352 
PRO HB3  H N N 353 
PRO HG2  H N N 354 
PRO HG3  H N N 355 
PRO HD2  H N N 356 
PRO HD3  H N N 357 
PRO HXT  H N N 358 
SER N    N N N 359 
SER CA   C N S 360 
SER C    C N N 361 
SER O    O N N 362 
SER CB   C N N 363 
SER OG   O N N 364 
SER OXT  O N N 365 
SER H    H N N 366 
SER H2   H N N 367 
SER HA   H N N 368 
SER HB2  H N N 369 
SER HB3  H N N 370 
SER HG   H N N 371 
SER HXT  H N N 372 
THR N    N N N 373 
THR CA   C N S 374 
THR C    C N N 375 
THR O    O N N 376 
THR CB   C N R 377 
THR OG1  O N N 378 
THR CG2  C N N 379 
THR OXT  O N N 380 
THR H    H N N 381 
THR H2   H N N 382 
THR HA   H N N 383 
THR HB   H N N 384 
THR HG1  H N N 385 
THR HG21 H N N 386 
THR HG22 H N N 387 
THR HG23 H N N 388 
THR HXT  H N N 389 
TRP N    N N N 390 
TRP CA   C N S 391 
TRP C    C N N 392 
TRP O    O N N 393 
TRP CB   C N N 394 
TRP CG   C Y N 395 
TRP CD1  C Y N 396 
TRP CD2  C Y N 397 
TRP NE1  N Y N 398 
TRP CE2  C Y N 399 
TRP CE3  C Y N 400 
TRP CZ2  C Y N 401 
TRP CZ3  C Y N 402 
TRP CH2  C Y N 403 
TRP OXT  O N N 404 
TRP H    H N N 405 
TRP H2   H N N 406 
TRP HA   H N N 407 
TRP HB2  H N N 408 
TRP HB3  H N N 409 
TRP HD1  H N N 410 
TRP HE1  H N N 411 
TRP HE3  H N N 412 
TRP HZ2  H N N 413 
TRP HZ3  H N N 414 
TRP HH2  H N N 415 
TRP HXT  H N N 416 
TYR N    N N N 417 
TYR CA   C N S 418 
TYR C    C N N 419 
TYR O    O N N 420 
TYR CB   C N N 421 
TYR CG   C Y N 422 
TYR CD1  C Y N 423 
TYR CD2  C Y N 424 
TYR CE1  C Y N 425 
TYR CE2  C Y N 426 
TYR CZ   C Y N 427 
TYR OH   O N N 428 
TYR OXT  O N N 429 
TYR H    H N N 430 
TYR H2   H N N 431 
TYR HA   H N N 432 
TYR HB2  H N N 433 
TYR HB3  H N N 434 
TYR HD1  H N N 435 
TYR HD2  H N N 436 
TYR HE1  H N N 437 
TYR HE2  H N N 438 
TYR HH   H N N 439 
TYR HXT  H N N 440 
VAL N    N N N 441 
VAL CA   C N S 442 
VAL C    C N N 443 
VAL O    O N N 444 
VAL CB   C N N 445 
VAL CG1  C N N 446 
VAL CG2  C N N 447 
VAL OXT  O N N 448 
VAL H    H N N 449 
VAL H2   H N N 450 
VAL HA   H N N 451 
VAL HB   H N N 452 
VAL HG11 H N N 453 
VAL HG12 H N N 454 
VAL HG13 H N N 455 
VAL HG21 H N N 456 
VAL HG22 H N N 457 
VAL HG23 H N N 458 
VAL HXT  H N N 459 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
4WI O1  C8   doub N N 1   
4WI C8  N2   sing N N 2   
4WI C8  C5   sing N N 3   
4WI N2  C7   sing N N 4   
4WI C4  C5   sing N N 5   
4WI C4  C2   sing N N 6   
4WI C5  C6   sing N N 7   
4WI N5  C3   doub N N 8   
4WI C3  C2   sing N N 9   
4WI C7  C6   sing N N 10  
4WI C2  N1   sing N N 11  
4WI N1  C1   sing N N 12  
4WI F1  C22  sing N N 13  
4WI O3  C13  doub N N 14  
4WI C1  C9   sing N N 15  
4WI C1  O2   doub N N 16  
4WI F3  C22  sing N N 17  
4WI C23 C15  sing N N 18  
4WI C22 F2   sing N N 19  
4WI C22 C21  sing N N 20  
4WI C9  N3   sing N N 21  
4WI C9  C12  sing N N 22  
4WI C13 N3   sing N N 23  
4WI C13 C14  sing N N 24  
4WI N4  C21  sing N N 25  
4WI N4  C14  sing N N 26  
4WI C19 C18  sing N N 27  
4WI N3  C10  sing N N 28  
4WI C21 O4   doub N N 29  
4WI C12 C18  sing N N 30  
4WI C12 C11  sing N N 31  
4WI C14 C15  sing N N 32  
4WI C15 C17  sing N N 33  
4WI C15 C16  sing N N 34  
4WI C18 C20  sing N N 35  
4WI C18 C11  sing N N 36  
4WI C10 C11  sing N N 37  
4WI C3  H33  sing N N 38  
4WI C6  H5   sing N N 39  
4WI C6  H6   sing N N 40  
4WI C7  H7   sing N N 41  
4WI C7  H8   sing N N 42  
4WI C10 H11  sing N N 43  
4WI C10 H12  sing N N 44  
4WI C5  H4   sing N N 45  
4WI C9  H10  sing N N 46  
4WI C11 H13  sing N N 47  
4WI C12 H14  sing N N 48  
4WI C19 H23  sing N N 49  
4WI C19 H24  sing N N 50  
4WI C19 H25  sing N N 51  
4WI C20 H26  sing N N 52  
4WI C20 H27  sing N N 53  
4WI C20 H28  sing N N 54  
4WI C16 H17  sing N N 55  
4WI C16 H19  sing N N 56  
4WI C16 H18  sing N N 57  
4WI C17 H20  sing N N 58  
4WI C17 H21  sing N N 59  
4WI C17 H22  sing N N 60  
4WI C23 H29  sing N N 61  
4WI C23 H30  sing N N 62  
4WI C23 H31  sing N N 63  
4WI C4  H2   sing N N 64  
4WI C4  H3   sing N N 65  
4WI C2  H32  sing N N 66  
4WI C14 H15  sing N N 67  
4WI N5  H36  sing N N 68  
4WI N2  H9   sing N N 69  
4WI N1  H1   sing N N 70  
4WI N4  H16  sing N N 71  
ALA N   CA   sing N N 72  
ALA N   H    sing N N 73  
ALA N   H2   sing N N 74  
ALA CA  C    sing N N 75  
ALA CA  CB   sing N N 76  
ALA CA  HA   sing N N 77  
ALA C   O    doub N N 78  
ALA C   OXT  sing N N 79  
ALA CB  HB1  sing N N 80  
ALA CB  HB2  sing N N 81  
ALA CB  HB3  sing N N 82  
ALA OXT HXT  sing N N 83  
ARG N   CA   sing N N 84  
ARG N   H    sing N N 85  
ARG N   H2   sing N N 86  
ARG CA  C    sing N N 87  
ARG CA  CB   sing N N 88  
ARG CA  HA   sing N N 89  
ARG C   O    doub N N 90  
ARG C   OXT  sing N N 91  
ARG CB  CG   sing N N 92  
ARG CB  HB2  sing N N 93  
ARG CB  HB3  sing N N 94  
ARG CG  CD   sing N N 95  
ARG CG  HG2  sing N N 96  
ARG CG  HG3  sing N N 97  
ARG CD  NE   sing N N 98  
ARG CD  HD2  sing N N 99  
ARG CD  HD3  sing N N 100 
ARG NE  CZ   sing N N 101 
ARG NE  HE   sing N N 102 
ARG CZ  NH1  sing N N 103 
ARG CZ  NH2  doub N N 104 
ARG NH1 HH11 sing N N 105 
ARG NH1 HH12 sing N N 106 
ARG NH2 HH21 sing N N 107 
ARG NH2 HH22 sing N N 108 
ARG OXT HXT  sing N N 109 
ASN N   CA   sing N N 110 
ASN N   H    sing N N 111 
ASN N   H2   sing N N 112 
ASN CA  C    sing N N 113 
ASN CA  CB   sing N N 114 
ASN CA  HA   sing N N 115 
ASN C   O    doub N N 116 
ASN C   OXT  sing N N 117 
ASN CB  CG   sing N N 118 
ASN CB  HB2  sing N N 119 
ASN CB  HB3  sing N N 120 
ASN CG  OD1  doub N N 121 
ASN CG  ND2  sing N N 122 
ASN ND2 HD21 sing N N 123 
ASN ND2 HD22 sing N N 124 
ASN OXT HXT  sing N N 125 
ASP N   CA   sing N N 126 
ASP N   H    sing N N 127 
ASP N   H2   sing N N 128 
ASP CA  C    sing N N 129 
ASP CA  CB   sing N N 130 
ASP CA  HA   sing N N 131 
ASP C   O    doub N N 132 
ASP C   OXT  sing N N 133 
ASP CB  CG   sing N N 134 
ASP CB  HB2  sing N N 135 
ASP CB  HB3  sing N N 136 
ASP CG  OD1  doub N N 137 
ASP CG  OD2  sing N N 138 
ASP OD2 HD2  sing N N 139 
ASP OXT HXT  sing N N 140 
CYS N   CA   sing N N 141 
CYS N   H    sing N N 142 
CYS N   H2   sing N N 143 
CYS CA  C    sing N N 144 
CYS CA  CB   sing N N 145 
CYS CA  HA   sing N N 146 
CYS C   O    doub N N 147 
CYS C   OXT  sing N N 148 
CYS CB  SG   sing N N 149 
CYS CB  HB2  sing N N 150 
CYS CB  HB3  sing N N 151 
CYS SG  HG   sing N N 152 
CYS OXT HXT  sing N N 153 
GLN N   CA   sing N N 154 
GLN N   H    sing N N 155 
GLN N   H2   sing N N 156 
GLN CA  C    sing N N 157 
GLN CA  CB   sing N N 158 
GLN CA  HA   sing N N 159 
GLN C   O    doub N N 160 
GLN C   OXT  sing N N 161 
GLN CB  CG   sing N N 162 
GLN CB  HB2  sing N N 163 
GLN CB  HB3  sing N N 164 
GLN CG  CD   sing N N 165 
GLN CG  HG2  sing N N 166 
GLN CG  HG3  sing N N 167 
GLN CD  OE1  doub N N 168 
GLN CD  NE2  sing N N 169 
GLN NE2 HE21 sing N N 170 
GLN NE2 HE22 sing N N 171 
GLN OXT HXT  sing N N 172 
GLU N   CA   sing N N 173 
GLU N   H    sing N N 174 
GLU N   H2   sing N N 175 
GLU CA  C    sing N N 176 
GLU CA  CB   sing N N 177 
GLU CA  HA   sing N N 178 
GLU C   O    doub N N 179 
GLU C   OXT  sing N N 180 
GLU CB  CG   sing N N 181 
GLU CB  HB2  sing N N 182 
GLU CB  HB3  sing N N 183 
GLU CG  CD   sing N N 184 
GLU CG  HG2  sing N N 185 
GLU CG  HG3  sing N N 186 
GLU CD  OE1  doub N N 187 
GLU CD  OE2  sing N N 188 
GLU OE2 HE2  sing N N 189 
GLU OXT HXT  sing N N 190 
GLY N   CA   sing N N 191 
GLY N   H    sing N N 192 
GLY N   H2   sing N N 193 
GLY CA  C    sing N N 194 
GLY CA  HA2  sing N N 195 
GLY CA  HA3  sing N N 196 
GLY C   O    doub N N 197 
GLY C   OXT  sing N N 198 
GLY OXT HXT  sing N N 199 
HIS N   CA   sing N N 200 
HIS N   H    sing N N 201 
HIS N   H2   sing N N 202 
HIS CA  C    sing N N 203 
HIS CA  CB   sing N N 204 
HIS CA  HA   sing N N 205 
HIS C   O    doub N N 206 
HIS C   OXT  sing N N 207 
HIS CB  CG   sing N N 208 
HIS CB  HB2  sing N N 209 
HIS CB  HB3  sing N N 210 
HIS CG  ND1  sing Y N 211 
HIS CG  CD2  doub Y N 212 
HIS ND1 CE1  doub Y N 213 
HIS ND1 HD1  sing N N 214 
HIS CD2 NE2  sing Y N 215 
HIS CD2 HD2  sing N N 216 
HIS CE1 NE2  sing Y N 217 
HIS CE1 HE1  sing N N 218 
HIS NE2 HE2  sing N N 219 
HIS OXT HXT  sing N N 220 
HOH O   H1   sing N N 221 
HOH O   H2   sing N N 222 
ILE N   CA   sing N N 223 
ILE N   H    sing N N 224 
ILE N   H2   sing N N 225 
ILE CA  C    sing N N 226 
ILE CA  CB   sing N N 227 
ILE CA  HA   sing N N 228 
ILE C   O    doub N N 229 
ILE C   OXT  sing N N 230 
ILE CB  CG1  sing N N 231 
ILE CB  CG2  sing N N 232 
ILE CB  HB   sing N N 233 
ILE CG1 CD1  sing N N 234 
ILE CG1 HG12 sing N N 235 
ILE CG1 HG13 sing N N 236 
ILE CG2 HG21 sing N N 237 
ILE CG2 HG22 sing N N 238 
ILE CG2 HG23 sing N N 239 
ILE CD1 HD11 sing N N 240 
ILE CD1 HD12 sing N N 241 
ILE CD1 HD13 sing N N 242 
ILE OXT HXT  sing N N 243 
LEU N   CA   sing N N 244 
LEU N   H    sing N N 245 
LEU N   H2   sing N N 246 
LEU CA  C    sing N N 247 
LEU CA  CB   sing N N 248 
LEU CA  HA   sing N N 249 
LEU C   O    doub N N 250 
LEU C   OXT  sing N N 251 
LEU CB  CG   sing N N 252 
LEU CB  HB2  sing N N 253 
LEU CB  HB3  sing N N 254 
LEU CG  CD1  sing N N 255 
LEU CG  CD2  sing N N 256 
LEU CG  HG   sing N N 257 
LEU CD1 HD11 sing N N 258 
LEU CD1 HD12 sing N N 259 
LEU CD1 HD13 sing N N 260 
LEU CD2 HD21 sing N N 261 
LEU CD2 HD22 sing N N 262 
LEU CD2 HD23 sing N N 263 
LEU OXT HXT  sing N N 264 
LYS N   CA   sing N N 265 
LYS N   H    sing N N 266 
LYS N   H2   sing N N 267 
LYS CA  C    sing N N 268 
LYS CA  CB   sing N N 269 
LYS CA  HA   sing N N 270 
LYS C   O    doub N N 271 
LYS C   OXT  sing N N 272 
LYS CB  CG   sing N N 273 
LYS CB  HB2  sing N N 274 
LYS CB  HB3  sing N N 275 
LYS CG  CD   sing N N 276 
LYS CG  HG2  sing N N 277 
LYS CG  HG3  sing N N 278 
LYS CD  CE   sing N N 279 
LYS CD  HD2  sing N N 280 
LYS CD  HD3  sing N N 281 
LYS CE  NZ   sing N N 282 
LYS CE  HE2  sing N N 283 
LYS CE  HE3  sing N N 284 
LYS NZ  HZ1  sing N N 285 
LYS NZ  HZ2  sing N N 286 
LYS NZ  HZ3  sing N N 287 
LYS OXT HXT  sing N N 288 
MET N   CA   sing N N 289 
MET N   H    sing N N 290 
MET N   H2   sing N N 291 
MET CA  C    sing N N 292 
MET CA  CB   sing N N 293 
MET CA  HA   sing N N 294 
MET C   O    doub N N 295 
MET C   OXT  sing N N 296 
MET CB  CG   sing N N 297 
MET CB  HB2  sing N N 298 
MET CB  HB3  sing N N 299 
MET CG  SD   sing N N 300 
MET CG  HG2  sing N N 301 
MET CG  HG3  sing N N 302 
MET SD  CE   sing N N 303 
MET CE  HE1  sing N N 304 
MET CE  HE2  sing N N 305 
MET CE  HE3  sing N N 306 
MET OXT HXT  sing N N 307 
PHE N   CA   sing N N 308 
PHE N   H    sing N N 309 
PHE N   H2   sing N N 310 
PHE CA  C    sing N N 311 
PHE CA  CB   sing N N 312 
PHE CA  HA   sing N N 313 
PHE C   O    doub N N 314 
PHE C   OXT  sing N N 315 
PHE CB  CG   sing N N 316 
PHE CB  HB2  sing N N 317 
PHE CB  HB3  sing N N 318 
PHE CG  CD1  doub Y N 319 
PHE CG  CD2  sing Y N 320 
PHE CD1 CE1  sing Y N 321 
PHE CD1 HD1  sing N N 322 
PHE CD2 CE2  doub Y N 323 
PHE CD2 HD2  sing N N 324 
PHE CE1 CZ   doub Y N 325 
PHE CE1 HE1  sing N N 326 
PHE CE2 CZ   sing Y N 327 
PHE CE2 HE2  sing N N 328 
PHE CZ  HZ   sing N N 329 
PHE OXT HXT  sing N N 330 
PRO N   CA   sing N N 331 
PRO N   CD   sing N N 332 
PRO N   H    sing N N 333 
PRO CA  C    sing N N 334 
PRO CA  CB   sing N N 335 
PRO CA  HA   sing N N 336 
PRO C   O    doub N N 337 
PRO C   OXT  sing N N 338 
PRO CB  CG   sing N N 339 
PRO CB  HB2  sing N N 340 
PRO CB  HB3  sing N N 341 
PRO CG  CD   sing N N 342 
PRO CG  HG2  sing N N 343 
PRO CG  HG3  sing N N 344 
PRO CD  HD2  sing N N 345 
PRO CD  HD3  sing N N 346 
PRO OXT HXT  sing N N 347 
SER N   CA   sing N N 348 
SER N   H    sing N N 349 
SER N   H2   sing N N 350 
SER CA  C    sing N N 351 
SER CA  CB   sing N N 352 
SER CA  HA   sing N N 353 
SER C   O    doub N N 354 
SER C   OXT  sing N N 355 
SER CB  OG   sing N N 356 
SER CB  HB2  sing N N 357 
SER CB  HB3  sing N N 358 
SER OG  HG   sing N N 359 
SER OXT HXT  sing N N 360 
THR N   CA   sing N N 361 
THR N   H    sing N N 362 
THR N   H2   sing N N 363 
THR CA  C    sing N N 364 
THR CA  CB   sing N N 365 
THR CA  HA   sing N N 366 
THR C   O    doub N N 367 
THR C   OXT  sing N N 368 
THR CB  OG1  sing N N 369 
THR CB  CG2  sing N N 370 
THR CB  HB   sing N N 371 
THR OG1 HG1  sing N N 372 
THR CG2 HG21 sing N N 373 
THR CG2 HG22 sing N N 374 
THR CG2 HG23 sing N N 375 
THR OXT HXT  sing N N 376 
TRP N   CA   sing N N 377 
TRP N   H    sing N N 378 
TRP N   H2   sing N N 379 
TRP CA  C    sing N N 380 
TRP CA  CB   sing N N 381 
TRP CA  HA   sing N N 382 
TRP C   O    doub N N 383 
TRP C   OXT  sing N N 384 
TRP CB  CG   sing N N 385 
TRP CB  HB2  sing N N 386 
TRP CB  HB3  sing N N 387 
TRP CG  CD1  doub Y N 388 
TRP CG  CD2  sing Y N 389 
TRP CD1 NE1  sing Y N 390 
TRP CD1 HD1  sing N N 391 
TRP CD2 CE2  doub Y N 392 
TRP CD2 CE3  sing Y N 393 
TRP NE1 CE2  sing Y N 394 
TRP NE1 HE1  sing N N 395 
TRP CE2 CZ2  sing Y N 396 
TRP CE3 CZ3  doub Y N 397 
TRP CE3 HE3  sing N N 398 
TRP CZ2 CH2  doub Y N 399 
TRP CZ2 HZ2  sing N N 400 
TRP CZ3 CH2  sing Y N 401 
TRP CZ3 HZ3  sing N N 402 
TRP CH2 HH2  sing N N 403 
TRP OXT HXT  sing N N 404 
TYR N   CA   sing N N 405 
TYR N   H    sing N N 406 
TYR N   H2   sing N N 407 
TYR CA  C    sing N N 408 
TYR CA  CB   sing N N 409 
TYR CA  HA   sing N N 410 
TYR C   O    doub N N 411 
TYR C   OXT  sing N N 412 
TYR CB  CG   sing N N 413 
TYR CB  HB2  sing N N 414 
TYR CB  HB3  sing N N 415 
TYR CG  CD1  doub Y N 416 
TYR CG  CD2  sing Y N 417 
TYR CD1 CE1  sing Y N 418 
TYR CD1 HD1  sing N N 419 
TYR CD2 CE2  doub Y N 420 
TYR CD2 HD2  sing N N 421 
TYR CE1 CZ   doub Y N 422 
TYR CE1 HE1  sing N N 423 
TYR CE2 CZ   sing Y N 424 
TYR CE2 HE2  sing N N 425 
TYR CZ  OH   sing N N 426 
TYR OH  HH   sing N N 427 
TYR OXT HXT  sing N N 428 
VAL N   CA   sing N N 429 
VAL N   H    sing N N 430 
VAL N   H2   sing N N 431 
VAL CA  C    sing N N 432 
VAL CA  CB   sing N N 433 
VAL CA  HA   sing N N 434 
VAL C   O    doub N N 435 
VAL C   OXT  sing N N 436 
VAL CB  CG1  sing N N 437 
VAL CB  CG2  sing N N 438 
VAL CB  HB   sing N N 439 
VAL CG1 HG11 sing N N 440 
VAL CG1 HG12 sing N N 441 
VAL CG1 HG13 sing N N 442 
VAL CG2 HG21 sing N N 443 
VAL CG2 HG22 sing N N 444 
VAL CG2 HG23 sing N N 445 
VAL OXT HXT  sing N N 446 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' 'P30 GM133893' 1 
'Department of Energy (DOE, United States)'                                                'United States' KP1607011      2 
'Other government'                                                                         ?               DE-SC0012704   3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   7NF5 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9BO4 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.021911 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.004077 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.018622 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.008891 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
F ? ? 8.95735 ?       ? ? 7.27484  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
H ? ? 0.51345 0.48472 ? ? 24.73122 6.32584  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N    . SER A 1 1   ? -34.22780 -3.65163  -35.03520 1.000 51.00575  ? 1   SER A N    1 
ATOM   2    C CA   . SER A 1 1   ? -33.77955 -4.79091  -34.18869 1.000 41.12567  ? 1   SER A CA   1 
ATOM   3    C C    . SER A 1 1   ? -32.25887 -4.94253  -34.25516 1.000 47.22854  ? 1   SER A C    1 
ATOM   4    O O    . SER A 1 1   ? -31.55106 -4.01056  -34.63822 1.000 45.28221  ? 1   SER A O    1 
ATOM   5    C CB   . SER A 1 1   ? -34.48030 -6.07839  -34.62240 1.000 57.63760  ? 1   SER A CB   1 
ATOM   6    O OG   . SER A 1 1   ? -34.19302 -6.38960  -35.97218 1.000 58.74024  ? 1   SER A OG   1 
ATOM   7    H H1   . SER A 1 1   ? -33.52077 -3.27134  -35.41937 1.000 61.20067  ? 1   SER A H1   1 
ATOM   8    H H2   . SER A 1 1   ? -34.78267 -3.94961  -35.66404 1.000 61.20067  ? 1   SER A H2   1 
ATOM   9    H H3   . SER A 1 1   ? -34.64797 -3.05276  -34.52834 1.000 61.20067  ? 1   SER A H3   1 
ATOM   10   H HA   . SER A 1 1   ? -34.01811 -4.62820  -33.26267 1.000 49.34458  ? 1   SER A HA   1 
ATOM   11   H HB2  . SER A 1 1   ? -34.17431 -6.80718  -34.06013 1.000 69.15889  ? 1   SER A HB2  1 
ATOM   12   H HB3  . SER A 1 1   ? -35.43835 -5.96300  -34.52380 1.000 69.15889  ? 1   SER A HB3  1 
ATOM   13   H HG   . SER A 1 1   ? -34.75914 -6.93512  -36.26800 1.000 70.48206  ? 1   SER A HG   1 
ATOM   14   N N    . GLY A 1 2   ? -31.76028 -6.11501  -33.88513 1.000 44.98276  ? 2   GLY A N    1 
ATOM   15   C CA   . GLY A 1 2   ? -30.34845 -6.28759  -33.62247 1.000 44.63353  ? 2   GLY A CA   1 
ATOM   16   C C    . GLY A 1 2   ? -30.00812 -5.95375  -32.18039 1.000 43.72141  ? 2   GLY A C    1 
ATOM   17   O O    . GLY A 1 2   ? -30.77716 -5.32457  -31.45603 1.000 51.71027  ? 2   GLY A O    1 
ATOM   18   H H    . GLY A 1 2   ? -32.22737 -6.82936  -33.77959 1.000 53.97308  ? 2   GLY A H    1 
ATOM   19   H HA2  . GLY A 1 2   ? -30.09602 -7.20807  -33.79538 1.000 53.55401  ? 2   GLY A HA2  1 
ATOM   20   H HA3  . GLY A 1 2   ? -29.83614 -5.70494  -34.20467 1.000 53.55401  ? 2   GLY A HA3  1 
ATOM   21   N N    . PHE A 1 3   ? -28.83234 -6.40382  -31.75215 1.000 36.85541  ? 3   PHE A N    1 
ATOM   22   C CA   . PHE A 1 3   ? -28.40746 -6.17383  -30.37529 1.000 37.59799  ? 3   PHE A CA   1 
ATOM   23   C C    . PHE A 1 3   ? -26.89133 -6.10437  -30.32928 1.000 39.80555  ? 3   PHE A C    1 
ATOM   24   O O    . PHE A 1 3   ? -26.21351 -7.07853  -30.66863 1.000 46.51785  ? 3   PHE A O    1 
ATOM   25   C CB   . PHE A 1 3   ? -28.92419 -7.26692  -29.43977 1.000 39.13579  ? 3   PHE A CB   1 
ATOM   26   C CG   . PHE A 1 3   ? -28.92679 -6.86044  -27.99632 1.000 40.19802  ? 3   PHE A CG   1 
ATOM   27   C CD1  . PHE A 1 3   ? -29.95845 -6.08914  -27.48481 1.000 45.01147  ? 3   PHE A CD1  1 
ATOM   28   C CD2  . PHE A 1 3   ? -27.89307 -7.23137  -27.15499 1.000 41.94612  ? 3   PHE A CD2  1 
ATOM   29   C CE1  . PHE A 1 3   ? -29.96218 -5.70084  -26.16092 1.000 43.82698  ? 3   PHE A CE1  1 
ATOM   30   C CE2  . PHE A 1 3   ? -27.89154 -6.84619  -25.82793 1.000 47.39703  ? 3   PHE A CE2  1 
ATOM   31   C CZ   . PHE A 1 3   ? -28.92776 -6.07979  -25.33102 1.000 43.64357  ? 3   PHE A CZ   1 
ATOM   32   H H    . PHE A 1 3   ? -28.26937 -6.84006  -32.23418 1.000 44.22026  ? 3   PHE A H    1 
ATOM   33   H HA   . PHE A 1 3   ? -28.76169 -5.32175  -30.07633 1.000 45.11136  ? 3   PHE A HA   1 
ATOM   34   H HB2  . PHE A 1 3   ? -29.83530 -7.48784  -29.68872 1.000 46.95671  ? 3   PHE A HB2  1 
ATOM   35   H HB3  . PHE A 1 3   ? -28.35724 -8.04902  -29.52802 1.000 46.95671  ? 3   PHE A HB3  1 
ATOM   36   H HD1  . PHE A 1 3   ? -30.65720 -5.82999  -28.04113 1.000 54.00754  ? 3   PHE A HD1  1 
ATOM   37   H HD2  . PHE A 1 3   ? -27.19208 -7.74516  -27.48594 1.000 50.32912  ? 3   PHE A HD2  1 
ATOM   38   H HE1  . PHE A 1 3   ? -30.66079 -5.18460  -25.82876 1.000 52.58615  ? 3   PHE A HE1  1 
ATOM   39   H HE2  . PHE A 1 3   ? -27.19335 -7.10278  -25.26974 1.000 56.87021  ? 3   PHE A HE2  1 
ATOM   40   H HZ   . PHE A 1 3   ? -28.92793 -5.81967  -24.43813 1.000 52.36606  ? 3   PHE A HZ   1 
ATOM   41   N N    . ARG A 1 4   ? -26.37261 -4.96048  -29.88773 1.000 40.65054  ? 4   ARG A N    1 
ATOM   42   C CA   . ARG A 1 4   ? -24.95070 -4.66430  -29.91728 1.000 43.09708  ? 4   ARG A CA   1 
ATOM   43   C C    . ARG A 1 4   ? -24.46561 -4.24299  -28.54060 1.000 47.42336  ? 4   ARG A C    1 
ATOM   44   O O    . ARG A 1 4   ? -25.21263 -3.64857  -27.75844 1.000 37.16774  ? 4   ARG A O    1 
ATOM   45   C CB   . ARG A 1 4   ? -24.64663 -3.53057  -30.89899 1.000 41.04046  ? 4   ARG A CB   1 
ATOM   46   C CG   . ARG A 1 4   ? -24.46069 -3.96536  -32.31851 1.000 43.77145  ? 4   ARG A CG   1 
ATOM   47   C CD   . ARG A 1 4   ? -23.11225 -4.62249  -32.48052 1.000 49.76546  ? 4   ARG A CD   1 
ATOM   48   N NE   . ARG A 1 4   ? -22.82473 -4.93924  -33.87128 1.000 51.41462  ? 4   ARG A NE   1 
ATOM   49   C CZ   . ARG A 1 4   ? -21.60427 -5.11845  -34.35426 1.000 57.82795  ? 4   ARG A CZ   1 
ATOM   50   N NH1  . ARG A 1 4   ? -20.53251 -4.98457  -33.58836 1.000 64.40194  ? 4   ARG A NH1  1 
ATOM   51   N NH2  . ARG A 1 4   ? -21.45486 -5.43285  -35.63843 1.000 46.74637  ? 4   ARG A NH2  1 
ATOM   52   H H    . ARG A 1 4   ? -26.84343 -4.32173  -29.55618 1.000 48.77442  ? 4   ARG A H    1 
ATOM   53   H HA   . ARG A 1 4   ? -24.47213 -5.46600  -30.18025 1.000 51.71027  ? 4   ARG A HA   1 
ATOM   54   H HB2  . ARG A 1 4   ? -25.38433 -2.90099  -30.88062 1.000 49.24232  ? 4   ARG A HB2  1 
ATOM   55   H HB3  . ARG A 1 4   ? -23.82853 -3.09131  -30.61853 1.000 49.24232  ? 4   ARG A HB3  1 
ATOM   56   H HG2  . ARG A 1 4   ? -25.14982 -4.60450  -32.55829 1.000 52.51951  ? 4   ARG A HG2  1 
ATOM   57   H HG3  . ARG A 1 4   ? -24.50440 -3.19446  -32.90563 1.000 52.51951  ? 4   ARG A HG3  1 
ATOM   58   H HD2  . ARG A 1 4   ? -22.42306 -4.02095  -32.15793 1.000 59.71232  ? 4   ARG A HD2  1 
ATOM   59   H HD3  . ARG A 1 4   ? -23.09635 -5.44837  -31.97202 1.000 59.71232  ? 4   ARG A HD3  1 
ATOM   60   H HE   . ARG A 1 4   ? -23.48816 -5.01479  -34.41327 1.000 61.69131  ? 4   ARG A HE   1 
ATOM   61   H HH11 . ARG A 1 4   ? -20.62031 -4.77705  -32.75840 1.000 77.27610  ? 4   ARG A HH11 1 
ATOM   62   H HH12 . ARG A 1 4   ? -19.74861 -5.10513  -33.92086 1.000 77.27610  ? 4   ARG A HH12 1 
ATOM   63   H HH21 . ARG A 1 4   ? -22.14568 -5.51729  -36.14364 1.000 56.08941  ? 4   ARG A HH21 1 
ATOM   64   H HH22 . ARG A 1 4   ? -20.66747 -5.55162  -35.96326 1.000 56.08941  ? 4   ARG A HH22 1 
ATOM   65   N N    . LYS A 1 5   ? -23.19673 -4.52546  -28.25635 1.000 51.73104  ? 5   LYS A N    1 
ATOM   66   C CA   . LYS A 1 5   ? -22.56240 -3.89026  -27.11132 1.000 48.64546  ? 5   LYS A CA   1 
ATOM   67   C C    . LYS A 1 5   ? -22.36792 -2.41967  -27.44903 1.000 44.80604  ? 5   LYS A C    1 
ATOM   68   O O    . LYS A 1 5   ? -21.72905 -2.07974  -28.45118 1.000 49.54677  ? 5   LYS A O    1 
ATOM   69   C CB   . LYS A 1 5   ? -21.23841 -4.55076  -26.75494 1.000 46.19022  ? 5   LYS A CB   1 
ATOM   70   C CG   . LYS A 1 5   ? -20.72875 -4.09813  -25.39124 1.000 44.71969  ? 5   LYS A CG   1 
ATOM   71   C CD   . LYS A 1 5   ? -19.76399 -5.08579  -24.77941 1.000 60.97316  ? 5   LYS A CD   1 
ATOM   72   C CE   . LYS A 1 5   ? -20.46726 -6.35451  -24.32711 1.000 49.49918  ? 5   LYS A CE   1 
ATOM   73   N NZ   . LYS A 1 5   ? -19.55937 -7.18934  -23.49843 1.000 61.67185  ? 5   LYS A NZ   1 
ATOM   74   H H    . LYS A 1 5   ? -22.69724 -5.06687  -28.70019 1.000 62.07102  ? 5   LYS A H    1 
ATOM   75   H HA   . LYS A 1 5   ? -23.12670 -3.98400  -26.32795 1.000 58.36833  ? 5   LYS A HA   1 
ATOM   76   H HB2  . LYS A 1 5   ? -21.35781 -5.51309  -26.73122 1.000 55.42204  ? 5   LYS A HB2  1 
ATOM   77   H HB3  . LYS A 1 5   ? -20.57437 -4.31518  -27.42162 1.000 55.42204  ? 5   LYS A HB3  1 
ATOM   78   H HG2  . LYS A 1 5   ? -20.26884 -3.24977  -25.48953 1.000 53.65740  ? 5   LYS A HG2  1 
ATOM   79   H HG3  . LYS A 1 5   ? -21.48151 -3.99942  -24.78750 1.000 53.65740  ? 5   LYS A HG3  1 
ATOM   80   H HD2  . LYS A 1 5   ? -19.09366 -5.32820  -25.43728 1.000 73.16157  ? 5   LYS A HD2  1 
ATOM   81   H HD3  . LYS A 1 5   ? -19.33940 -4.68188  -24.00644 1.000 73.16157  ? 5   LYS A HD3  1 
ATOM   82   H HE2  . LYS A 1 5   ? -21.24462 -6.12258  -23.79530 1.000 59.39279  ? 5   LYS A HE2  1 
ATOM   83   H HE3  . LYS A 1 5   ? -20.73789 -6.86971  -25.10314 1.000 59.39279  ? 5   LYS A HE3  1 
ATOM   84   H HZ1  . LYS A 1 5   ? -19.27830 -6.72520  -22.79297 1.000 73.99999  ? 5   LYS A HZ1  1 
ATOM   85   H HZ2  . LYS A 1 5   ? -19.98834 -7.91548  -23.21417 1.000 73.99999  ? 5   LYS A HZ2  1 
ATOM   86   H HZ3  . LYS A 1 5   ? -18.85350 -7.44040  -23.97887 1.000 73.99999  ? 5   LYS A HZ3  1 
ATOM   87   N N    . MET A 1 6   ? -22.94424 -1.55454  -26.62983 1.000 37.13456  ? 6   MET A N    1 
ATOM   88   C CA   . MET A 1 6   ? -23.13847 -0.15836  -26.97759 1.000 36.10237  ? 6   MET A CA   1 
ATOM   89   C C    . MET A 1 6   ? -22.64747 0.69905   -25.82721 1.000 37.78009  ? 6   MET A C    1 
ATOM   90   O O    . MET A 1 6   ? -22.95171 0.41902   -24.66337 1.000 27.69495  ? 6   MET A O    1 
ATOM   91   C CB   . MET A 1 6   ? -24.61645 0.10417   -27.26949 1.000 36.71559  ? 6   MET A CB   1 
ATOM   92   C CG   . MET A 1 6   ? -24.92016 1.41896   -27.93707 1.000 46.46764  ? 6   MET A CG   1 
ATOM   93   S SD   . MET A 1 6   ? -26.68901 1.55919   -28.29070 1.000 46.44260  ? 6   MET A SD   1 
ATOM   94   C CE   . MET A 1 6   ? -26.90398 0.28997   -29.53200 1.000 40.65309  ? 6   MET A CE   1 
ATOM   95   H H    . MET A 1 6   ? -23.23819 -1.75827  -25.84773 1.000 44.55525  ? 6   MET A H    1 
ATOM   96   H HA   . MET A 1 6   ? -22.62856 0.07255   -27.76978 1.000 43.31661  ? 6   MET A HA   1 
ATOM   97   H HB2  . MET A 1 6   ? -24.94171 -0.59848  -27.85378 1.000 44.05248  ? 6   MET A HB2  1 
ATOM   98   H HB3  . MET A 1 6   ? -25.10110 0.08793   -26.42940 1.000 44.05248  ? 6   MET A HB3  1 
ATOM   99   H HG2  . MET A 1 6   ? -24.66349 2.14756   -27.35041 1.000 55.75494  ? 6   MET A HG2  1 
ATOM   100  H HG3  . MET A 1 6   ? -24.43208 1.47859   -28.77321 1.000 55.75494  ? 6   MET A HG3  1 
ATOM   101  H HE1  . MET A 1 6   ? -27.47216 0.63306   -30.23936 1.000 48.77748  ? 6   MET A HE1  1 
ATOM   102  H HE2  . MET A 1 6   ? -26.03581 0.05013   -29.89208 1.000 48.77748  ? 6   MET A HE2  1 
ATOM   103  H HE3  . MET A 1 6   ? -27.31786 -0.48569  -29.12217 1.000 48.77748  ? 6   MET A HE3  1 
ATOM   104  N N    . ALA A 1 7   ? -21.87986 1.72761   -26.15179 1.000 31.72371  ? 7   ALA A N    1 
ATOM   105  C CA   . ALA A 1 7   ? -21.39068 2.66723   -25.15946 1.000 32.84159  ? 7   ALA A CA   1 
ATOM   106  C C    . ALA A 1 7   ? -22.19006 3.96007   -25.23684 1.000 34.56732  ? 7   ALA A C    1 
ATOM   107  O O    . ALA A 1 7   ? -22.80114 4.28383   -26.25865 1.000 36.03051  ? 7   ALA A O    1 
ATOM   108  C CB   . ALA A 1 7   ? -19.90045 2.95154   -25.36454 1.000 29.01284  ? 7   ALA A CB   1 
ATOM   109  H H    . ALA A 1 7   ? -21.62526 1.90419   -26.95403 1.000 38.06223  ? 7   ALA A H    1 
ATOM   110  H HA   . ALA A 1 7   ? -21.49716 2.29047   -24.27198 1.000 39.40368  ? 7   ALA A HA   1 
ATOM   111  H HB1  . ALA A 1 7   ? -19.40927 2.11688   -25.30992 1.000 34.80918  ? 7   ALA A HB1  1 
ATOM   112  H HB2  . ALA A 1 7   ? -19.77297 3.35381   -26.23794 1.000 34.80918  ? 7   ALA A HB2  1 
ATOM   113  H HB3  . ALA A 1 7   ? -19.59688 3.55988   -24.67268 1.000 34.80918  ? 7   ALA A HB3  1 
ATOM   114  N N    . PHE A 1 8   ? -22.19071 4.69173   -24.12862 1.000 34.36034  ? 8   PHE A N    1 
ATOM   115  C CA   . PHE A 1 8   ? -22.79610 6.00852   -24.12329 1.000 32.41874  ? 8   PHE A CA   1 
ATOM   116  C C    . PHE A 1 8   ? -22.04448 6.92388   -25.08528 1.000 30.20909  ? 8   PHE A C    1 
ATOM   117  O O    . PHE A 1 8   ? -20.84458 6.74139   -25.31843 1.000 31.90476  ? 8   PHE A O    1 
ATOM   118  C CB   . PHE A 1 8   ? -22.76212 6.61439   -22.72505 1.000 30.61942  ? 8   PHE A CB   1 
ATOM   119  C CG   . PHE A 1 8   ? -23.63259 5.91326   -21.74185 1.000 31.36550  ? 8   PHE A CG   1 
ATOM   120  C CD1  . PHE A 1 8   ? -24.97812 6.21187   -21.65857 1.000 39.80312  ? 8   PHE A CD1  1 
ATOM   121  C CD2  . PHE A 1 8   ? -23.10516 4.96404   -20.88679 1.000 38.66800  ? 8   PHE A CD2  1 
ATOM   122  C CE1  . PHE A 1 8   ? -25.78604 5.57068   -20.74245 1.000 40.37402  ? 8   PHE A CE1  1 
ATOM   123  C CE2  . PHE A 1 8   ? -23.90766 4.32041   -19.97229 1.000 43.93998  ? 8   PHE A CE2  1 
ATOM   124  C CZ   . PHE A 1 8   ? -25.25154 4.62597   -19.89887 1.000 36.13468  ? 8   PHE A CZ   1 
ATOM   125  H H    . PHE A 1 8   ? -21.85041 4.44875   -23.37712 1.000 41.22618  ? 8   PHE A H    1 
ATOM   126  H HA   . PHE A 1 8   ? -23.72183 5.93724   -24.40408 1.000 38.89626  ? 8   PHE A HA   1 
ATOM   127  H HB2  . PHE A 1 8   ? -21.85176 6.57799   -22.39215 1.000 36.73707  ? 8   PHE A HB2  1 
ATOM   128  H HB3  . PHE A 1 8   ? -23.05939 7.53620   -22.77800 1.000 36.73707  ? 8   PHE A HB3  1 
ATOM   129  H HD1  . PHE A 1 8   ? -25.34348 6.85183   -22.22589 1.000 47.75751  ? 8   PHE A HD1  1 
ATOM   130  H HD2  . PHE A 1 8   ? -22.19924 4.75821   -20.92976 1.000 46.39537  ? 8   PHE A HD2  1 
ATOM   131  H HE1  . PHE A 1 8   ? -26.69157 5.77736   -20.69559 1.000 48.44259  ? 8   PHE A HE1  1 
ATOM   132  H HE2  . PHE A 1 8   ? -23.54448 3.67993   -19.40415 1.000 52.72174  ? 8   PHE A HE2  1 
ATOM   133  H HZ   . PHE A 1 8   ? -25.79448 4.19359   -19.27988 1.000 43.35539  ? 8   PHE A HZ   1 
ATOM   134  N N    . PRO A 1 9   ? -22.72059 7.91364   -25.66147 1.000 36.49671  ? 9   PRO A N    1 
ATOM   135  C CA   . PRO A 1 9   ? -21.99135 8.98674   -26.34413 1.000 31.95535  ? 9   PRO A CA   1 
ATOM   136  C C    . PRO A 1 9   ? -20.97523 9.59974   -25.39123 1.000 32.25250  ? 9   PRO A C    1 
ATOM   137  O O    . PRO A 1 9   ? -21.25487 9.81580   -24.20974 1.000 34.49588  ? 9   PRO A O    1 
ATOM   138  C CB   . PRO A 1 9   ? -23.09266 9.97587   -26.73776 1.000 33.50696  ? 9   PRO A CB   1 
ATOM   139  C CG   . PRO A 1 9   ? -24.33669 9.13455   -26.82059 1.000 41.38487  ? 9   PRO A CG   1 
ATOM   140  C CD   . PRO A 1 9   ? -24.18266 8.08990   -25.74908 1.000 34.26242  ? 9   PRO A CD   1 
ATOM   141  H HA   . PRO A 1 9   ? -21.55335 8.67372   -27.15103 1.000 38.34019  ? 9   PRO A HA   1 
ATOM   142  H HB2  . PRO A 1 9   ? -23.18033 10.66362  -26.05937 1.000 40.20213  ? 9   PRO A HB2  1 
ATOM   143  H HB3  . PRO A 1 9   ? -22.88622 10.37993  -27.59509 1.000 40.20213  ? 9   PRO A HB3  1 
ATOM   144  H HG2  . PRO A 1 9   ? -25.11814 9.68524   -26.65633 1.000 49.65562  ? 9   PRO A HG2  1 
ATOM   145  H HG3  . PRO A 1 9   ? -24.39861 8.72377   -27.69713 1.000 49.65562  ? 9   PRO A HG3  1 
ATOM   146  H HD2  . PRO A 1 9   ? -24.54446 8.40361   -24.90552 1.000 41.10867  ? 9   PRO A HD2  1 
ATOM   147  H HD3  . PRO A 1 9   ? -24.61602 7.26176   -26.00846 1.000 41.10867  ? 9   PRO A HD3  1 
ATOM   148  N N    . SER A 1 10  ? -19.77507 9.84915   -25.90413 1.000 36.36868  ? 10  SER A N    1 
ATOM   149  C CA   . SER A 1 10  ? -18.65765 10.28541  -25.08149 1.000 35.41308  ? 10  SER A CA   1 
ATOM   150  C C    . SER A 1 10  ? -18.43854 11.79091  -25.12535 1.000 40.96267  ? 10  SER A C    1 
ATOM   151  O O    . SER A 1 10  ? -17.53926 12.28828  -24.44195 1.000 41.16860  ? 10  SER A O    1 
ATOM   152  C CB   . SER A 1 10  ? -17.37522 9.56577   -25.51935 1.000 39.16647  ? 10  SER A CB   1 
ATOM   153  O OG   . SER A 1 10  ? -17.01290 9.92543   -26.84339 1.000 38.41689  ? 10  SER A OG   1 
ATOM   154  H H    . SER A 1 10  ? -19.58248 9.77111   -26.73865 1.000 43.63619  ? 10  SER A H    1 
ATOM   155  H HA   . SER A 1 10  ? -18.83928 10.04281  -24.16005 1.000 42.48947  ? 10  SER A HA   1 
ATOM   156  H HB2  . SER A 1 10  ? -16.65513 9.81258   -24.91815 1.000 46.99354  ? 10  SER A HB2  1 
ATOM   157  H HB3  . SER A 1 10  ? -17.52404 8.60793   -25.48315 1.000 46.99354  ? 10  SER A HB3  1 
ATOM   158  H HG   . SER A 1 10  ? -16.25180 9.62042   -27.02588 1.000 46.09404  ? 10  SER A HG   1 
ATOM   159  N N    . GLY A 1 11  ? -19.24768 12.52623  -25.89162 1.000 39.43584  ? 11  GLY A N    1 
ATOM   160  C CA   . GLY A 1 11  ? -18.98482 13.94481  -26.08741 1.000 37.60321  ? 11  GLY A CA   1 
ATOM   161  C C    . GLY A 1 11  ? -18.83767 14.70850  -24.78756 1.000 40.23619  ? 11  GLY A C    1 
ATOM   162  O O    . GLY A 1 11  ? -17.89521 15.48443  -24.60919 1.000 41.54964  ? 11  GLY A O    1 
ATOM   163  H H    . GLY A 1 11  ? -19.94339 12.23012  -26.30138 1.000 47.31678  ? 11  GLY A H    1 
ATOM   164  H HA2  . GLY A 1 11  ? -18.16423 14.04919  -26.59401 1.000 45.11762  ? 11  GLY A HA2  1 
ATOM   165  H HA3  . GLY A 1 11  ? -19.71702 14.33777  -26.58777 1.000 45.11762  ? 11  GLY A HA3  1 
ATOM   166  N N    . LYS A 1 12  ? -19.77362 14.50226  -23.85929 1.000 37.98430  ? 12  LYS A N    1 
ATOM   167  C CA   . LYS A 1 12  ? -19.73619 15.22948  -22.59499 1.000 35.60880  ? 12  LYS A CA   1 
ATOM   168  C C    . LYS A 1 12  ? -18.44077 14.96770  -21.83876 1.000 41.24418  ? 12  LYS A C    1 
ATOM   169  O O    . LYS A 1 12  ? -17.90621 15.86648  -21.17852 1.000 40.23072  ? 12  LYS A O    1 
ATOM   170  C CB   . LYS A 1 12  ? -20.94038 14.83968  -21.73902 1.000 38.24100  ? 12  LYS A CB   1 
ATOM   171  C CG   . LYS A 1 12  ? -22.22893 15.52634  -22.14931 1.000 34.60307  ? 12  LYS A CG   1 
ATOM   172  C CD   . LYS A 1 12  ? -23.45260 14.76183  -21.68545 1.000 41.26256  ? 12  LYS A CD   1 
ATOM   173  C CE   . LYS A 1 12  ? -24.69592 15.63198  -21.75604 1.000 47.07237  ? 12  LYS A CE   1 
ATOM   174  N NZ   . LYS A 1 12  ? -24.60739 16.63967  -22.84655 1.000 67.05891  ? 12  LYS A NZ   1 
ATOM   175  H H    . LYS A 1 12  ? -20.43153 13.95389  -23.93698 1.000 45.57493  ? 12  LYS A H    1 
ATOM   176  H HA   . LYS A 1 12  ? -19.78560 16.18029  -22.78049 1.000 42.72434  ? 12  LYS A HA   1 
ATOM   177  H HB2  . LYS A 1 12  ? -21.07846 13.88237  -21.81251 1.000 45.88298  ? 12  LYS A HB2  1 
ATOM   178  H HB3  . LYS A 1 12  ? -20.75796 15.07873  -20.81681 1.000 45.88298  ? 12  LYS A HB3  1 
ATOM   179  H HG2  . LYS A 1 12  ? -22.25816 16.41224  -21.75532 1.000 41.51746  ? 12  LYS A HG2  1 
ATOM   180  H HG3  . LYS A 1 12  ? -22.26178 15.59214  -23.11651 1.000 41.51746  ? 12  LYS A HG3  1 
ATOM   181  H HD2  . LYS A 1 12  ? -23.58613 13.98854  -22.25562 1.000 49.50884  ? 12  LYS A HD2  1 
ATOM   182  H HD3  . LYS A 1 12  ? -23.32770 14.47861  -20.76617 1.000 49.50884  ? 12  LYS A HD3  1 
ATOM   183  H HE2  . LYS A 1 12  ? -25.46937 15.07106  -21.92352 1.000 56.48062  ? 12  LYS A HE2  1 
ATOM   184  H HE3  . LYS A 1 12  ? -24.80395 16.10364  -20.91534 1.000 56.48062  ? 12  LYS A HE3  1 
ATOM   185  H HZ1  . LYS A 1 12  ? -25.40495 17.00975  -22.98452 1.000 80.46447  ? 12  LYS A HZ1  1 
ATOM   186  H HZ2  . LYS A 1 12  ? -24.02741 17.27746  -22.62531 1.000 80.46447  ? 12  LYS A HZ2  1 
ATOM   187  H HZ3  . LYS A 1 12  ? -24.33546 16.25046  -23.59932 1.000 80.46447  ? 12  LYS A HZ3  1 
ATOM   188  N N    . VAL A 1 13  ? -17.92440 13.74208  -21.91784 1.000 42.52216  ? 13  VAL A N    1 
ATOM   189  C CA   . VAL A 1 13  ? -16.72227 13.39465  -21.17034 1.000 38.15511  ? 13  VAL A CA   1 
ATOM   190  C C    . VAL A 1 13  ? -15.47278 13.86627  -21.90349 1.000 37.80863  ? 13  VAL A C    1 
ATOM   191  O O    . VAL A 1 13  ? -14.51410 14.32988  -21.27663 1.000 37.33505  ? 13  VAL A O    1 
ATOM   192  C CB   . VAL A 1 13  ? -16.69767 11.87925  -20.90432 1.000 34.29588  ? 13  VAL A CB   1 
ATOM   193  C CG1  . VAL A 1 13  ? -15.43897 11.49177  -20.13202 1.000 30.29963  ? 13  VAL A CG1  1 
ATOM   194  C CG2  . VAL A 1 13  ? -17.95940 11.46981  -20.15418 1.000 28.28582  ? 13  VAL A CG2  1 
ATOM   195  H H    . VAL A 1 13  ? -18.24816 13.10180  -22.39199 1.000 51.02036  ? 13  VAL A H    1 
ATOM   196  H HA   . VAL A 1 13  ? -16.74276 13.84980  -20.31399 1.000 45.77990  ? 13  VAL A HA   1 
ATOM   197  H HB   . VAL A 1 13  ? -16.67761 11.39949  -21.74713 1.000 41.14883  ? 13  VAL A HB   1 
ATOM   198  H HG11 . VAL A 1 13  ? -15.11724 12.26573  -19.64378 1.000 36.35333  ? 13  VAL A HG11 1 
ATOM   199  H HG12 . VAL A 1 13  ? -15.65566 10.77692  -19.51321 1.000 36.35333  ? 13  VAL A HG12 1 
ATOM   200  H HG13 . VAL A 1 13  ? -14.76293 11.19223  -20.75983 1.000 36.35333  ? 13  VAL A HG13 1 
ATOM   201  H HG21 . VAL A 1 13  ? -18.70902 11.47668  -20.76975 1.000 33.93675  ? 13  VAL A HG21 1 
ATOM   202  H HG22 . VAL A 1 13  ? -17.83649 10.57816  -19.79258 1.000 33.93675  ? 13  VAL A HG22 1 
ATOM   203  H HG23 . VAL A 1 13  ? -18.11709 12.10004  -19.43388 1.000 33.93675  ? 13  VAL A HG23 1 
ATOM   204  N N    . GLU A 1 14  ? -15.46277 13.76544  -23.23617 1.000 33.61761  ? 14  GLU A N    1 
ATOM   205  C CA   . GLU A 1 14  ? -14.33647 14.27634  -24.01304 1.000 40.44417  ? 14  GLU A CA   1 
ATOM   206  C C    . GLU A 1 14  ? -13.97555 15.69807  -23.59681 1.000 45.22709  ? 14  GLU A C    1 
ATOM   207  O O    . GLU A 1 14  ? -12.79377 16.03350  -23.45176 1.000 42.50897  ? 14  GLU A O    1 
ATOM   208  C CB   . GLU A 1 14  ? -14.66624 14.23379  -25.50785 1.000 41.30561  ? 14  GLU A CB   1 
ATOM   209  C CG   . GLU A 1 14  ? -14.83365 12.83332  -26.07610 1.000 39.78235  ? 14  GLU A CG   1 
ATOM   210  C CD   . GLU A 1 14  ? -15.39190 12.83415  -27.48716 1.000 40.12321  ? 14  GLU A CD   1 
ATOM   211  O OE1  . GLU A 1 14  ? -14.84765 13.55522  -28.34830 1.000 42.41825  ? 14  GLU A OE1  1 
ATOM   212  O OE2  . GLU A 1 14  ? -16.38260 12.11549  -27.73426 1.000 43.19514  ? 14  GLU A OE2  1 
ATOM   213  H H    . GLU A 1 14  ? -16.08855 13.40986  -23.70687 1.000 40.33491  ? 14  GLU A H    1 
ATOM   214  H HA   . GLU A 1 14  ? -13.56715 13.70724  -23.85439 1.000 48.52677  ? 14  GLU A HA   1 
ATOM   215  H HB2  . GLU A 1 14  ? -15.49787 14.71103  -25.65458 1.000 49.56050  ? 14  GLU A HB2  1 
ATOM   216  H HB3  . GLU A 1 14  ? -13.94643 14.66389  -25.99550 1.000 49.56050  ? 14  GLU A HB3  1 
ATOM   217  H HG2  . GLU A 1 14  ? -13.96855 12.39503  -26.09624 1.000 47.73259  ? 14  GLU A HG2  1 
ATOM   218  H HG3  . GLU A 1 14  ? -15.44521 12.33453  -25.51208 1.000 47.73259  ? 14  GLU A HG3  1 
ATOM   219  N N    . GLY A 1 15  ? -14.98237 16.54607  -23.39195 1.000 44.98214  ? 15  GLY A N    1 
ATOM   220  C CA   . GLY A 1 15  ? -14.75566 17.92960  -23.02253 1.000 41.45982  ? 15  GLY A CA   1 
ATOM   221  C C    . GLY A 1 15  ? -14.12074 18.14362  -21.66566 1.000 44.78899  ? 15  GLY A C    1 
ATOM   222  O O    . GLY A 1 15  ? -13.81721 19.29059  -21.32253 1.000 38.67417  ? 15  GLY A O    1 
ATOM   223  H H    . GLY A 1 15  ? -15.81343 16.33653  -23.46290 1.000 53.97234  ? 15  GLY A H    1 
ATOM   224  H HA2  . GLY A 1 15  ? -14.17485 18.33460  -23.68550 1.000 49.74555  ? 15  GLY A HA2  1 
ATOM   225  H HA3  . GLY A 1 15  ? -15.60790 18.39283  -23.02412 1.000 49.74555  ? 15  GLY A HA3  1 
ATOM   226  N N    . CYS A 1 16  ? -13.90805 17.08069  -20.88837 1.000 39.94600  ? 16  CYS A N    1 
ATOM   227  C CA   . CYS A 1 16  ? -13.30269 17.18194  -19.56888 1.000 39.43402  ? 16  CYS A CA   1 
ATOM   228  C C    . CYS A 1 16  ? -11.92428 16.54258  -19.49528 1.000 37.63713  ? 16  CYS A C    1 
ATOM   229  O O    . CYS A 1 16  ? -11.31982 16.53086  -18.41740 1.000 34.69366  ? 16  CYS A O    1 
ATOM   230  C CB   . CYS A 1 16  ? -14.21475 16.53404  -18.52194 1.000 42.49572  ? 16  CYS A CB   1 
ATOM   231  S SG   . CYS A 1 16  ? -15.87940 17.21814  -18.46375 1.000 43.41968  ? 16  CYS A SG   1 
ATOM   232  H H    . CYS A 1 16  ? -14.11154 16.27552  -21.11171 1.000 47.92897  ? 16  CYS A H    1 
ATOM   233  H HA   . CYS A 1 16  ? -13.20697 18.12177  -19.34878 1.000 47.31460  ? 16  CYS A HA   1 
ATOM   234  H HB2  . CYS A 1 16  ? -14.29261 15.58812  -18.72212 1.000 50.98864  ? 16  CYS A HB2  1 
ATOM   235  H HB3  . CYS A 1 16  ? -13.81611 16.65607  -17.64610 1.000 50.98864  ? 16  CYS A HB3  1 
ATOM   236  H HG   . CYS A 1 16  ? -15.80937 18.40049  -18.27101 1.000 52.09739  ? 16  CYS A HG   1 
ATOM   237  N N    . MET A 1 17  ? -11.41029 16.01222  -20.60093 1.000 38.98065  ? 17  MET A N    1 
ATOM   238  C CA   . MET A 1 17  ? -10.15013 15.28357  -20.58427 1.000 41.74570  ? 17  MET A CA   1 
ATOM   239  C C    . MET A 1 17  ? -8.99731  16.23505  -20.87439 1.000 39.23492  ? 17  MET A C    1 
ATOM   240  O O    . MET A 1 17  ? -9.04658  17.01387  -21.83346 1.000 43.96931  ? 17  MET A O    1 
ATOM   241  C CB   . MET A 1 17  ? -10.16532 14.13782  -21.59779 1.000 39.89374  ? 17  MET A CB   1 
ATOM   242  C CG   . MET A 1 17  ? -11.19864 13.04878  -21.30778 1.000 41.28434  ? 17  MET A CG   1 
ATOM   243  S SD   . MET A 1 17  ? -11.26382 12.52569  -19.57754 1.000 36.10365  ? 17  MET A SD   1 
ATOM   244  C CE   . MET A 1 17  ? -9.56349  12.03654  -19.30533 1.000 35.59075  ? 17  MET A CE   1 
ATOM   245  H H    . MET A 1 17  ? -11.77647 16.06222  -21.37746 1.000 46.77055  ? 17  MET A H    1 
ATOM   246  H HA   . MET A 1 17  ? -10.02541 14.89486  -19.70436 1.000 50.08861  ? 17  MET A HA   1 
ATOM   247  H HB2  . MET A 1 17  ? -10.36292 14.50329  -22.47431 1.000 47.86626  ? 17  MET A HB2  1 
ATOM   248  H HB3  . MET A 1 17  ? -9.29083  13.71814  -21.60278 1.000 47.86626  ? 17  MET A HB3  1 
ATOM   249  H HG2  . MET A 1 17  ? -12.07723 13.38359  -21.54629 1.000 49.53497  ? 17  MET A HG2  1 
ATOM   250  H HG3  . MET A 1 17  ? -10.98472 12.26815  -21.84235 1.000 49.53497  ? 17  MET A HG3  1 
ATOM   251  H HE1  . MET A 1 17  ? -8.99197  12.81448  -19.40061 1.000 42.70267  ? 17  MET A HE1  1 
ATOM   252  H HE2  . MET A 1 17  ? -9.47921  11.67178  -18.41049 1.000 42.70267  ? 17  MET A HE2  1 
ATOM   253  H HE3  . MET A 1 17  ? -9.31940  11.36450  -19.96083 1.000 42.70267  ? 17  MET A HE3  1 
ATOM   254  N N    . VAL A 1 18  ? -7.96185  16.16284  -20.03980 1.000 33.88769  ? 18  VAL A N    1 
ATOM   255  C CA   . VAL A 1 18  ? -6.80196  17.03634  -20.12685 1.000 34.91899  ? 18  VAL A CA   1 
ATOM   256  C C    . VAL A 1 18  ? -5.54732  16.19487  -19.93371 1.000 39.84342  ? 18  VAL A C    1 
ATOM   257  O O    . VAL A 1 18  ? -5.59903  15.05144  -19.47861 1.000 38.82570  ? 18  VAL A O    1 
ATOM   258  C CB   . VAL A 1 18  ? -6.84987  18.17463  -19.08357 1.000 39.39194  ? 18  VAL A CB   1 
ATOM   259  C CG1  . VAL A 1 18  ? -8.04762  19.07859  -19.33999 1.000 37.50286  ? 18  VAL A CG1  1 
ATOM   260  C CG2  . VAL A 1 18  ? -6.88945  17.60730  -17.65578 1.000 33.51307  ? 18  VAL A CG2  1 
ATOM   261  H H    . VAL A 1 18  ? -7.91034  15.59596  -19.39513 1.000 40.65900  ? 18  VAL A H    1 
ATOM   262  H HA   . VAL A 1 18  ? -6.76835  17.43429  -21.01082 1.000 41.89656  ? 18  VAL A HA   1 
ATOM   263  H HB   . VAL A 1 18  ? -6.04402  18.70809  -19.16673 1.000 47.26410  ? 18  VAL A HB   1 
ATOM   264  H HG11 . VAL A 1 18  ? -8.75223  18.85494  -18.71198 1.000 44.99720  ? 18  VAL A HG11 1 
ATOM   265  H HG12 . VAL A 1 18  ? -7.77768  20.00239  -19.21905 1.000 44.99720  ? 18  VAL A HG12 1 
ATOM   266  H HG13 . VAL A 1 18  ? -8.35834  18.94100  -20.24852 1.000 44.99720  ? 18  VAL A HG13 1 
ATOM   267  H HG21 . VAL A 1 18  ? -6.10072  17.06158  -17.51083 1.000 40.20946  ? 18  VAL A HG21 1 
ATOM   268  H HG22 . VAL A 1 18  ? -6.90329  18.34309  -17.02387 1.000 40.20946  ? 18  VAL A HG22 1 
ATOM   269  H HG23 . VAL A 1 18  ? -7.68872  17.06749  -17.55249 1.000 40.20946  ? 18  VAL A HG23 1 
ATOM   270  N N    . GLN A 1 19  ? -4.41164  16.78741  -20.28873 1.000 38.57854  ? 19  GLN A N    1 
ATOM   271  C CA   . GLN A 1 19  ? -3.10016  16.18912  -20.08522 1.000 39.33481  ? 19  GLN A CA   1 
ATOM   272  C C    . GLN A 1 19  ? -2.48917  16.72884  -18.79724 1.000 38.34295  ? 19  GLN A C    1 
ATOM   273  O O    . GLN A 1 19  ? -2.53552  17.93747  -18.53920 1.000 41.23144  ? 19  GLN A O    1 
ATOM   274  C CB   . GLN A 1 19  ? -2.18481  16.48833  -21.27290 1.000 37.53496  ? 19  GLN A CB   1 
ATOM   275  C CG   . GLN A 1 19  ? -0.77112  15.96029  -21.13822 1.000 43.80985  ? 19  GLN A CG   1 
ATOM   276  C CD   . GLN A 1 19  ? 0.15221   16.52397  -22.19914 1.000 51.16351  ? 19  GLN A CD   1 
ATOM   277  O OE1  . GLN A 1 19  ? 0.32919   17.73899  -22.30305 1.000 58.61757  ? 19  GLN A OE1  1 
ATOM   278  N NE2  . GLN A 1 19  ? 0.74080   15.64411  -22.99849 1.000 59.42325  ? 19  GLN A NE2  1 
ATOM   279  H H    . GLN A 1 19  ? -4.37565  17.56165  -20.66135 1.000 46.28802  ? 19  GLN A H    1 
ATOM   280  H HA   . GLN A 1 19  ? -3.18814  15.22688  -20.00005 1.000 47.19554  ? 19  GLN A HA   1 
ATOM   281  H HB2  . GLN A 1 19  ? -2.57101  16.08726  -22.06719 1.000 45.03572  ? 19  GLN A HB2  1 
ATOM   282  H HB3  . GLN A 1 19  ? -2.12712  17.45049  -21.38164 1.000 45.03572  ? 19  GLN A HB3  1 
ATOM   283  H HG2  . GLN A 1 19  ? -0.41998  16.20828  -20.26868 1.000 52.56559  ? 19  GLN A HG2  1 
ATOM   284  H HG3  . GLN A 1 19  ? -0.78189  14.99456  -21.22854 1.000 52.56559  ? 19  GLN A HG3  1 
ATOM   285  H HE21 . GLN A 1 19  ? 0.58912   14.80352  -22.89848 1.000 71.30167  ? 19  GLN A HE21 1 
ATOM   286  H HE22 . GLN A 1 19  ? 1.27409   15.91426  -23.61673 1.000 71.30167  ? 19  GLN A HE22 1 
ATOM   287  N N    . VAL A 1 20  ? -1.92422  15.83370  -17.99458 1.000 38.25498  ? 20  VAL A N    1 
ATOM   288  C CA   . VAL A 1 20  ? -1.25507  16.18999  -16.74847 1.000 37.84448  ? 20  VAL A CA   1 
ATOM   289  C C    . VAL A 1 20  ? 0.17196   15.66598  -16.81844 1.000 43.21214  ? 20  VAL A C    1 
ATOM   290  O O    . VAL A 1 20  ? 0.38872   14.45737  -16.97633 1.000 44.45387  ? 20  VAL A O    1 
ATOM   291  C CB   . VAL A 1 20  ? -1.98301  15.62310  -15.51951 1.000 38.87087  ? 20  VAL A CB   1 
ATOM   292  C CG1  . VAL A 1 20  ? -1.17776  15.90417  -14.25501 1.000 40.48034  ? 20  VAL A CG1  1 
ATOM   293  C CG2  . VAL A 1 20  ? -3.38039  16.21354  -15.40840 1.000 37.73199  ? 20  VAL A CG2  1 
ATOM   294  H H    . VAL A 1 20  ? -1.91551  14.98893  -18.15549 1.000 45.89975  ? 20  VAL A H    1 
ATOM   295  H HA   . VAL A 1 20  ? -1.22706  17.15621  -16.66758 1.000 45.40715  ? 20  VAL A HA   1 
ATOM   296  H HB   . VAL A 1 20  ? -2.07076  14.66213  -15.61818 1.000 46.63882  ? 20  VAL A HB   1 
ATOM   297  H HG11 . VAL A 1 20  ? -0.57804  16.64819  -14.42139 1.000 48.57018  ? 20  VAL A HG11 1 
ATOM   298  H HG12 . VAL A 1 20  ? -1.78826  16.12611  -13.53465 1.000 48.57018  ? 20  VAL A HG12 1 
ATOM   299  H HG13 . VAL A 1 20  ? -0.66680  15.11281  -14.02357 1.000 48.57018  ? 20  VAL A HG13 1 
ATOM   300  H HG21 . VAL A 1 20  ? -3.83007  15.81913  -14.64477 1.000 45.27215  ? 20  VAL A HG21 1 
ATOM   301  H HG22 . VAL A 1 20  ? -3.30906  17.17372  -15.29064 1.000 45.27215  ? 20  VAL A HG22 1 
ATOM   302  H HG23 . VAL A 1 20  ? -3.87239  16.01553  -16.22057 1.000 45.27215  ? 20  VAL A HG23 1 
ATOM   303  N N    . ILE A 1 21  ? 1.13997   16.57116  -16.69902 1.000 44.16639  ? 21  ILE A N    1 
ATOM   304  C CA   . ILE A 1 21  ? 2.55669   16.23100  -16.74455 1.000 44.29933  ? 21  ILE A CA   1 
ATOM   305  C C    . ILE A 1 21  ? 3.18757   16.63485  -15.41915 1.000 47.88069  ? 21  ILE A C    1 
ATOM   306  O O    . ILE A 1 21  ? 3.10789   17.80236  -15.01574 1.000 51.38865  ? 21  ILE A O    1 
ATOM   307  C CB   . ILE A 1 21  ? 3.27595   16.92086  -17.91486 1.000 42.88739  ? 21  ILE A CB   1 
ATOM   308  C CG1  . ILE A 1 21  ? 2.60084   16.58154  -19.24284 1.000 50.63068  ? 21  ILE A CG1  1 
ATOM   309  C CG2  . ILE A 1 21  ? 4.74346   16.51449  -17.95429 1.000 45.93600  ? 21  ILE A CG2  1 
ATOM   310  C CD1  . ILE A 1 21  ? 3.20982   17.30450  -20.42845 1.000 49.26514  ? 21  ILE A CD1  1 
ATOM   311  H H    . ILE A 1 21  ? 0.99493   17.41151  -16.58776 1.000 52.99345  ? 21  ILE A H    1 
ATOM   312  H HA   . ILE A 1 21  ? 2.64533   15.27056  -16.84748 1.000 53.15297  ? 21  ILE A HA   1 
ATOM   313  N N    . CYS A 1 22  ? 3.81425   15.67133  -14.74840 1.000 46.83050  ? 22  CYS A N    1 
ATOM   314  C CA   . CYS A 1 22  ? 4.64320   15.92054  -13.57285 1.000 44.36277  ? 22  CYS A CA   1 
ATOM   315  C C    . CYS A 1 22  ? 5.99661   15.27411  -13.83951 1.000 50.85244  ? 22  CYS A C    1 
ATOM   316  O O    . CYS A 1 22  ? 6.09639   14.04471  -13.90617 1.000 58.06280  ? 22  CYS A O    1 
ATOM   317  C CB   . CYS A 1 22  ? 3.99913   15.35826  -12.30552 1.000 53.34383  ? 22  CYS A CB   1 
ATOM   318  S SG   . CYS A 1 22  ? 4.96999   15.60246  -10.80146 1.000 56.06564  ? 22  CYS A SG   1 
ATOM   319  H H    . CYS A 1 22  ? 3.77279   14.83937  -14.96226 1.000 56.19038  ? 22  CYS A H    1 
ATOM   320  H HA   . CYS A 1 22  ? 4.76409   16.87398  -13.44157 1.000 53.22909  ? 22  CYS A HA   1 
ATOM   321  H HB2  . CYS A 1 22  ? 3.14210   15.79350  -12.17525 1.000 64.00636  ? 22  CYS A HB2  1 
ATOM   322  H HB3  . CYS A 1 22  ? 3.87223   14.40354  -12.42087 1.000 64.00636  ? 22  CYS A HB3  1 
ATOM   323  H HG   . CYS A 1 22  ? 5.09614   16.77947  -10.60468 1.000 67.27253  ? 22  CYS A HG   1 
ATOM   324  N N    . GLY A 1 23  ? 7.02782   16.09362  -14.01418 1.000 56.73591  ? 23  GLY A N    1 
ATOM   325  C CA   . GLY A 1 23  ? 8.34490   15.54972  -14.31413 1.000 54.34196  ? 23  GLY A CA   1 
ATOM   326  C C    . GLY A 1 23  ? 8.35954   14.90759  -15.68635 1.000 57.48031  ? 23  GLY A C    1 
ATOM   327  O O    . GLY A 1 23  ? 7.95168   15.51160  -16.68465 1.000 55.46277  ? 23  GLY A O    1 
ATOM   328  H H    . GLY A 1 23  ? 6.99284   16.95152  -13.96545 1.000 68.07686  ? 23  GLY A H    1 
ATOM   329  H HA2  . GLY A 1 23  ? 9.00531   16.25991  -14.29455 1.000 65.20412  ? 23  GLY A HA2  1 
ATOM   330  H HA3  . GLY A 1 23  ? 8.58153   14.88012  -13.65341 1.000 65.20412  ? 23  GLY A HA3  1 
ATOM   331  N N    . THR A 1 24  ? 8.84341   13.66645  -15.74560 1.000 60.60234  ? 24  THR A N    1 
ATOM   332  C CA   . THR A 1 24  ? 8.82644   12.92241  -16.99885 1.000 61.71559  ? 24  THR A CA   1 
ATOM   333  C C    . THR A 1 24  ? 7.45417   12.32106  -17.28324 1.000 60.28608  ? 24  THR A C    1 
ATOM   334  O O    . THR A 1 24  ? 7.07978   12.15960  -18.45055 1.000 60.51185  ? 24  THR A O    1 
ATOM   335  C CB   . THR A 1 24  ? 9.88285   11.81397  -16.96157 1.000 65.82527  ? 24  THR A CB   1 
ATOM   336  O OG1  . THR A 1 24  ? 10.26356  11.46286  -18.29805 1.000 74.92986  ? 24  THR A OG1  1 
ATOM   337  C CG2  . THR A 1 24  ? 9.34758   10.57148  -16.24103 1.000 71.15966  ? 24  THR A CG2  1 
ATOM   338  H H    . THR A 1 24  ? 9.18275   13.23917  -15.08086 1.000 72.71658  ? 24  THR A H    1 
ATOM   339  H HA   . THR A 1 24  ? 9.04755   13.52598  -17.72529 1.000 74.05248  ? 24  THR A HA   1 
ATOM   340  H HB   . THR A 1 24  ? 10.66070  12.13199  -16.47710 1.000 78.98410  ? 24  THR A HB   1 
ATOM   341  H HG1  . THR A 1 24  ? 10.90248  11.94594  -18.55107 1.000 89.90961  ? 24  THR A HG1  1 
ATOM   342  H HG21 . THR A 1 24  ? 10.08242  9.98742   -15.99653 1.000 85.38537  ? 24  THR A HG21 1 
ATOM   343  H HG22 . THR A 1 24  ? 8.87251   10.83323  -15.43686 1.000 85.38537  ? 24  THR A HG22 1 
ATOM   344  H HG23 . THR A 1 24  ? 8.74025   10.08703  -16.82185 1.000 85.38537  ? 24  THR A HG23 1 
ATOM   345  N N    . THR A 1 25  ? 6.69302   12.00448  -16.23972 1.000 57.30617  ? 25  THR A N    1 
ATOM   346  C CA   . THR A 1 25  ? 5.46003   11.24843  -16.40353 1.000 57.16232  ? 25  THR A CA   1 
ATOM   347  C C    . THR A 1 25  ? 4.36869   12.09621  -17.04572 1.000 51.78448  ? 25  THR A C    1 
ATOM   348  O O    . THR A 1 25  ? 4.21819   13.28387  -16.74718 1.000 53.51554  ? 25  THR A O    1 
ATOM   349  C CB   . THR A 1 25  ? 4.98926   10.72948  -15.04644 1.000 46.03199  ? 25  THR A CB   1 
ATOM   350  O OG1  . THR A 1 25  ? 6.10166   10.16189  -14.34408 1.000 52.91812  ? 25  THR A OG1  1 
ATOM   351  C CG2  . THR A 1 25  ? 3.91590   9.67332   -15.21909 1.000 57.20587  ? 25  THR A CG2  1 
ATOM   352  H H    . THR A 1 25  ? 6.86976   12.21662  -15.42525 1.000 68.76118  ? 25  THR A H    1 
ATOM   353  H HA   . THR A 1 25  ? 5.62509   10.49306  -16.98925 1.000 68.58856  ? 25  THR A HA   1 
ATOM   354  H HB   . THR A 1 25  ? 4.61503   11.46164  -14.53185 1.000 55.23215  ? 25  THR A HB   1 
ATOM   355  H HG1  . THR A 1 25  ? 6.41678   9.51603   -14.77902 1.000 63.49552  ? 25  THR A HG1  1 
ATOM   356  H HG21 . THR A 1 25  ? 4.12615   9.10767   -15.97852 1.000 68.64081  ? 25  THR A HG21 1 
ATOM   357  H HG22 . THR A 1 25  ? 3.86086   9.12290   -14.42228 1.000 68.64081  ? 25  THR A HG22 1 
ATOM   358  H HG23 . THR A 1 25  ? 3.05588   10.09587  -15.36983 1.000 68.64081  ? 25  THR A HG23 1 
ATOM   359  N N    . THR A 1 26  ? 3.60103   11.47002  -17.93481 1.000 53.95565  ? 26  THR A N    1 
ATOM   360  C CA   . THR A 1 26  ? 2.48051   12.11304  -18.60894 1.000 51.75964  ? 26  THR A CA   1 
ATOM   361  C C    . THR A 1 26  ? 1.28729   11.17181  -18.56985 1.000 46.58165  ? 26  THR A C    1 
ATOM   362  O O    . THR A 1 26  ? 1.37276   10.04231  -19.06199 1.000 48.79071  ? 26  THR A O    1 
ATOM   363  C CB   . THR A 1 26  ? 2.83256   12.45701  -20.05810 1.000 43.08576  ? 26  THR A CB   1 
ATOM   364  O OG1  . THR A 1 26  ? 4.10286   13.11680  -20.09992 1.000 60.39408  ? 26  THR A OG1  1 
ATOM   365  C CG2  . THR A 1 26  ? 1.77239   13.35948  -20.66077 1.000 48.94395  ? 26  THR A CG2  1 
ATOM   366  H H    . THR A 1 26  ? 3.71421   10.65030  -18.16901 1.000 64.74056  ? 26  THR A H    1 
ATOM   367  H HA   . THR A 1 26  ? 2.24918   12.93136  -18.14232 1.000 62.10534  ? 26  THR A HA   1 
ATOM   368  H HB   . THR A 1 26  ? 2.87608   11.64342  -20.58449 1.000 51.69668  ? 26  THR A HB   1 
ATOM   369  H HG1  . THR A 1 26  ? 4.10886   13.76284  -19.56309 1.000 72.46666  ? 26  THR A HG1  1 
ATOM   370  H HG21 . THR A 1 26  ? 1.50826   14.03618  -20.01795 1.000 58.72651  ? 26  THR A HG21 1 
ATOM   371  H HG22 . THR A 1 26  ? 2.12066   13.79705  -21.45332 1.000 58.72651  ? 26  THR A HG22 1 
ATOM   372  H HG23 . THR A 1 26  ? 0.99274   12.83726  -20.90640 1.000 58.72651  ? 26  THR A HG23 1 
ATOM   373  N N    . LEU A 1 27  ? 0.17810   11.63082  -17.99614 1.000 40.52114  ? 27  LEU A N    1 
ATOM   374  C CA   . LEU A 1 27  ? -1.03974  10.83355  -17.96635 1.000 37.67391  ? 27  LEU A CA   1 
ATOM   375  C C    . LEU A 1 27  ? -2.24193  11.76586  -18.06943 1.000 40.00840  ? 27  LEU A C    1 
ATOM   376  O O    . LEU A 1 27  ? -2.10208  12.97875  -18.25179 1.000 39.25552  ? 27  LEU A O    1 
ATOM   377  C CB   . LEU A 1 27  ? -1.07847  9.95076   -16.71427 1.000 36.93822  ? 27  LEU A CB   1 
ATOM   378  C CG   . LEU A 1 27  ? -0.85020  10.59981  -15.34762 1.000 42.64557  ? 27  LEU A CG   1 
ATOM   379  C CD1  . LEU A 1 27  ? -2.03983  11.44467  -14.92996 1.000 46.15790  ? 27  LEU A CD1  1 
ATOM   380  C CD2  . LEU A 1 27  ? -0.54630  9.52012   -14.30701 1.000 45.41990  ? 27  LEU A CD2  1 
ATOM   381  H H    . LEU A 1 27  ? 0.10795   12.40024  -17.61840 1.000 48.61914  ? 27  LEU A H    1 
ATOM   382  H HA   . LEU A 1 27  ? -1.06403  10.25029  -18.74103 1.000 45.20246  ? 27  LEU A HA   1 
ATOM   383  H HB2  . LEU A 1 27  ? -1.95384  9.53443   -16.67828 1.000 44.31963  ? 27  LEU A HB2  1 
ATOM   384  H HB3  . LEU A 1 27  ? -0.39238  9.27246   -16.81469 1.000 44.31963  ? 27  LEU A HB3  1 
ATOM   385  H HG   . LEU A 1 27  ? -0.08834  11.19769  -15.40252 1.000 51.16845  ? 27  LEU A HG   1 
ATOM   386  H HD11 . LEU A 1 27  ? -2.02713  12.27647  -15.42881 1.000 55.38325  ? 27  LEU A HD11 1 
ATOM   387  H HD12 . LEU A 1 27  ? -2.85621  10.95686  -15.12095 1.000 55.38325  ? 27  LEU A HD12 1 
ATOM   388  H HD13 . LEU A 1 27  ? -1.97876  11.62806  -13.97942 1.000 55.38325  ? 27  LEU A HD13 1 
ATOM   389  H HD21 . LEU A 1 27  ? -0.77932  8.65308   -14.67423 1.000 54.49765  ? 27  LEU A HD21 1 
ATOM   390  H HD22 . LEU A 1 27  ? 0.39941   9.54527   -14.09277 1.000 54.49765  ? 27  LEU A HD22 1 
ATOM   391  H HD23 . LEU A 1 27  ? -1.07081  9.69344   -13.50967 1.000 54.49765  ? 27  LEU A HD23 1 
ATOM   392  N N    . ASN A 1 28  ? -3.43272  11.18490  -17.96385 1.000 32.48818  ? 28  ASN A N    1 
ATOM   393  C CA   . ASN A 1 28  ? -4.67539  11.88745  -18.24547 1.000 36.30761  ? 28  ASN A CA   1 
ATOM   394  C C    . ASN A 1 28  ? -5.34752  12.36127  -16.96118 1.000 41.64175  ? 28  ASN A C    1 
ATOM   395  O O    . ASN A 1 28  ? -5.21679  11.74314  -15.90135 1.000 35.15321  ? 28  ASN A O    1 
ATOM   396  C CB   . ASN A 1 28  ? -5.62909  10.98224  -19.03163 1.000 39.59378  ? 28  ASN A CB   1 
ATOM   397  C CG   . ASN A 1 28  ? -5.00313  10.44576  -20.30813 1.000 40.44533  ? 28  ASN A CG   1 
ATOM   398  O OD1  . ASN A 1 28  ? -4.99553  11.12011  -21.33746 1.000 35.67765  ? 28  ASN A OD1  1 
ATOM   399  N ND2  . ASN A 1 28  ? -4.46544  9.23135   -20.24299 1.000 35.85445  ? 28  ASN A ND2  1 
ATOM   400  H H    . ASN A 1 28  ? -3.54698  10.36655  -17.72543 1.000 38.97958  ? 28  ASN A H    1 
ATOM   401  H HA   . ASN A 1 28  ? -4.48203  12.67583  -18.77647 1.000 43.56291  ? 28  ASN A HA   1 
ATOM   402  H HB2  . ASN A 1 28  ? -5.87730  10.22591  -18.47731 1.000 47.50631  ? 28  ASN A HB2  1 
ATOM   403  H HB3  . ASN A 1 28  ? -6.41958  11.48935  -19.27423 1.000 47.50631  ? 28  ASN A HB3  1 
ATOM   404  H HD21 . ASN A 1 28  ? -4.09928  8.88526   -20.93995 1.000 43.01911  ? 28  ASN A HD21 1 
ATOM   405  H HD22 . ASN A 1 28  ? -4.48385  8.79202   -19.50391 1.000 43.01911  ? 28  ASN A HD22 1 
ATOM   406  N N    . GLY A 1 29  ? -6.07485  13.47633  -17.07385 1.000 37.60395  ? 29  GLY A N    1 
ATOM   407  C CA   . GLY A 1 29  ? -6.80236  14.02500  -15.95382 1.000 34.70284  ? 29  GLY A CA   1 
ATOM   408  C C    . GLY A 1 29  ? -8.22465  14.37967  -16.35131 1.000 35.68091  ? 29  GLY A C    1 
ATOM   409  O O    . GLY A 1 29  ? -8.53399  14.58224  -17.52467 1.000 39.68571  ? 29  GLY A O    1 
ATOM   410  H H    . GLY A 1 29  ? -6.15697  13.93007  -17.79978 1.000 45.11851  ? 29  GLY A H    1 
ATOM   411  H HA2  . GLY A 1 29  ? -6.83297  13.37553  -15.23400 1.000 41.63717  ? 29  GLY A HA2  1 
ATOM   412  H HA3  . GLY A 1 29  ? -6.35842  14.82707  -15.63682 1.000 41.63717  ? 29  GLY A HA3  1 
ATOM   413  N N    . LEU A 1 30  ? -9.08878  14.44663  -15.33967 1.000 34.02876  ? 30  LEU A N    1 
ATOM   414  C CA   . LEU A 1 30  ? -10.49968 14.78126  -15.51087 1.000 33.41609  ? 30  LEU A CA   1 
ATOM   415  C C    . LEU A 1 30  ? -10.75083 16.17065  -14.93360 1.000 41.09350  ? 30  LEU A C    1 
ATOM   416  O O    . LEU A 1 30  ? -10.60284 16.38226  -13.72505 1.000 34.34196  ? 30  LEU A O    1 
ATOM   417  C CB   . LEU A 1 30  ? -11.39010 13.74260  -14.83069 1.000 37.57732  ? 30  LEU A CB   1 
ATOM   418  C CG   . LEU A 1 30  ? -12.89685 13.95113  -14.97496 1.000 35.75209  ? 30  LEU A CG   1 
ATOM   419  C CD1  . LEU A 1 30  ? -13.32890 13.70639  -16.40620 1.000 37.00586  ? 30  LEU A CD1  1 
ATOM   420  C CD2  . LEU A 1 30  ? -13.64610 13.04514  -14.02084 1.000 36.17775  ? 30  LEU A CD2  1 
ATOM   421  H H    . LEU A 1 30  ? -8.87347  14.29755  -14.52051 1.000 40.82828  ? 30  LEU A H    1 
ATOM   422  H HA   . LEU A 1 30  ? -10.71809 14.80026  -16.45577 1.000 40.09308  ? 30  LEU A HA   1 
ATOM   423  H HB2  . LEU A 1 30  ? -11.18337 12.87356  -15.20874 1.000 45.08656  ? 30  LEU A HB2  1 
ATOM   424  H HB3  . LEU A 1 30  ? -11.18944 13.74781  -13.88169 1.000 45.08656  ? 30  LEU A HB3  1 
ATOM   425  H HG   . LEU A 1 30  ? -13.11775 14.86868  -14.75090 1.000 42.89628  ? 30  LEU A HG   1 
ATOM   426  H HD11 . LEU A 1 30  ? -14.29800 13.69255  -16.44556 1.000 44.40081  ? 30  LEU A HD11 1 
ATOM   427  H HD12 . LEU A 1 30  ? -12.98526 14.41996  -16.96622 1.000 44.40081  ? 30  LEU A HD12 1 
ATOM   428  H HD13 . LEU A 1 30  ? -12.97363 12.85359  -16.70188 1.000 44.40081  ? 30  LEU A HD13 1 
ATOM   429  H HD21 . LEU A 1 30  ? -14.58948 13.26924  -14.04771 1.000 43.40707  ? 30  LEU A HD21 1 
ATOM   430  H HD22 . LEU A 1 30  ? -13.51720 12.12331  -14.29379 1.000 43.40707  ? 30  LEU A HD22 1 
ATOM   431  H HD23 . LEU A 1 30  ? -13.30045 13.17599  -13.12401 1.000 43.40707  ? 30  LEU A HD23 1 
ATOM   432  N N    . TRP A 1 31  ? -11.14617 17.10445  -15.79804 1.000 37.87225  ? 31  TRP A N    1 
ATOM   433  C CA   . TRP A 1 31  ? -11.24534 18.52455  -15.46051 1.000 38.14118  ? 31  TRP A CA   1 
ATOM   434  C C    . TRP A 1 31  ? -12.71725 18.87851  -15.27857 1.000 43.65382  ? 31  TRP A C    1 
ATOM   435  O O    . TRP A 1 31  ? -13.44621 19.07428  -16.25407 1.000 41.10169  ? 31  TRP A O    1 
ATOM   436  C CB   . TRP A 1 31  ? -10.59506 19.36992  -16.55349 1.000 38.89482  ? 31  TRP A CB   1 
ATOM   437  C CG   . TRP A 1 31  ? -10.61787 20.84860  -16.29833 1.000 49.39874  ? 31  TRP A CG   1 
ATOM   438  C CD1  . TRP A 1 31  ? -10.75494 21.47658  -15.09151 1.000 49.59941  ? 31  TRP A CD1  1 
ATOM   439  C CD2  . TRP A 1 31  ? -10.49987 21.88715  -17.27897 1.000 49.88818  ? 31  TRP A CD2  1 
ATOM   440  N NE1  . TRP A 1 31  ? -10.72968 22.84065  -15.26216 1.000 47.02806  ? 31  TRP A NE1  1 
ATOM   441  C CE2  . TRP A 1 31  ? -10.57159 23.11860  -16.59490 1.000 48.99499  ? 31  TRP A CE2  1 
ATOM   442  C CE3  . TRP A 1 31  ? -10.34292 21.89526  -18.66895 1.000 43.05334  ? 31  TRP A CE3  1 
ATOM   443  C CZ2  . TRP A 1 31  ? -10.49589 24.34355  -17.25440 1.000 48.91919  ? 31  TRP A CZ2  1 
ATOM   444  C CZ3  . TRP A 1 31  ? -10.26565 23.11173  -19.32053 1.000 45.17808  ? 31  TRP A CZ3  1 
ATOM   445  C CH2  . TRP A 1 31  ? -10.34165 24.31885  -18.61363 1.000 51.44948  ? 31  TRP A CH2  1 
ATOM   446  H H    . TRP A 1 31  ? -11.36913 16.93476  -16.61112 1.000 45.44047  ? 31  TRP A H    1 
ATOM   447  H HA   . TRP A 1 31  ? -10.79197 18.69058  -14.61921 1.000 45.76318  ? 31  TRP A HA   1 
ATOM   448  H HB2  . TRP A 1 31  ? -9.66657  19.10251  -16.63884 1.000 46.66756  ? 31  TRP A HB2  1 
ATOM   449  H HB3  . TRP A 1 31  ? -11.06433 19.21009  -17.38724 1.000 46.66756  ? 31  TRP A HB3  1 
ATOM   450  H HD1  . TRP A 1 31  ? -10.85127 21.04388  -14.27395 1.000 59.51306  ? 31  TRP A HD1  1 
ATOM   451  H HE1  . TRP A 1 31  ? -10.80140 23.42444  -14.63475 1.000 56.42744  ? 31  TRP A HE1  1 
ATOM   452  H HE3  . TRP A 1 31  ? -10.29160 21.09806  -19.14512 1.000 51.65778  ? 31  TRP A HE3  1 
ATOM   453  H HZ2  . TRP A 1 31  ? -10.54818 25.14687  -16.78874 1.000 58.69680  ? 31  TRP A HZ2  1 
ATOM   454  H HZ3  . TRP A 1 31  ? -10.16136 23.12923  -20.24450 1.000 54.20747  ? 31  TRP A HZ3  1 
ATOM   455  H HH2  . TRP A 1 31  ? -10.28597 25.12206  -19.07909 1.000 61.73315  ? 31  TRP A HH2  1 
ATOM   456  N N    . LEU A 1 32  ? -13.15144 18.96050  -14.02054 1.000 47.12064  ? 32  LEU A N    1 
ATOM   457  C CA   . LEU A 1 32  ? -14.51824 19.32690  -13.66545 1.000 47.53545  ? 32  LEU A CA   1 
ATOM   458  C C    . LEU A 1 32  ? -14.46628 20.56310  -12.77725 1.000 47.75199  ? 32  LEU A C    1 
ATOM   459  O O    . LEU A 1 32  ? -13.79992 20.55502  -11.73609 1.000 43.73724  ? 32  LEU A O    1 
ATOM   460  C CB   . LEU A 1 32  ? -15.22968 18.17045  -12.95721 1.000 46.31814  ? 32  LEU A CB   1 
ATOM   461  C CG   . LEU A 1 32  ? -15.30052 16.85703  -13.74597 1.000 44.58027  ? 32  LEU A CG   1 
ATOM   462  C CD1  . LEU A 1 32  ? -15.68573 15.69250  -12.84177 1.000 37.46730  ? 32  LEU A CD1  1 
ATOM   463  C CD2  . LEU A 1 32  ? -16.27882 16.96715  -14.90985 1.000 43.62139  ? 32  LEU A CD2  1 
ATOM   464  H H    . LEU A 1 32  ? -12.65532 18.80306  -13.33593 1.000 56.53853  ? 32  LEU A H    1 
ATOM   465  H HA   . LEU A 1 32  ? -15.02230 19.54438  -14.46515 1.000 57.03631  ? 32  LEU A HA   1 
ATOM   466  H HB2  . LEU A 1 32  ? -14.75991 17.98562  -12.12892 1.000 55.57553  ? 32  LEU A HB2  1 
ATOM   467  H HB3  . LEU A 1 32  ? -16.14090 18.44385  -12.76792 1.000 55.57553  ? 32  LEU A HB3  1 
ATOM   468  H HG   . LEU A 1 32  ? -14.41925 16.67708  -14.10912 1.000 53.49010  ? 32  LEU A HG   1 
ATOM   469  H HD11 . LEU A 1 32  ? -16.40261 15.97418  -12.25217 1.000 44.95453  ? 32  LEU A HD11 1 
ATOM   470  H HD12 . LEU A 1 32  ? -15.98199 14.95033  -13.39161 1.000 44.95453  ? 32  LEU A HD12 1 
ATOM   471  H HD13 . LEU A 1 32  ? -14.91207 15.42896  -12.31937 1.000 44.95453  ? 32  LEU A HD13 1 
ATOM   472  H HD21 . LEU A 1 32  ? -16.16718 16.19790  -15.49010 1.000 52.33944  ? 32  LEU A HD21 1 
ATOM   473  H HD22 . LEU A 1 32  ? -17.18358 16.98969  -14.56084 1.000 52.33944  ? 32  LEU A HD22 1 
ATOM   474  H HD23 . LEU A 1 32  ? -16.09371 17.78230  -15.40194 1.000 52.33944  ? 32  LEU A HD23 1 
ATOM   475  N N    . ASP A 1 33  ? -15.15547 21.61996  -13.19176 1.000 49.18364  ? 33  ASP A N    1 
ATOM   476  C CA   . ASP A 1 33  ? -15.11599 22.91312  -12.48351 1.000 53.22459  ? 33  ASP A CA   1 
ATOM   477  C C    . ASP A 1 33  ? -13.65047 23.36431  -12.46290 1.000 49.14200  ? 33  ASP A C    1 
ATOM   478  O O    . ASP A 1 33  ? -12.96008 23.25207  -13.48853 1.000 46.59275  ? 33  ASP A O    1 
ATOM   479  C CB   . ASP A 1 33  ? -15.77249 22.78045  -11.12021 1.000 55.64976  ? 33  ASP A CB   1 
ATOM   480  C CG   . ASP A 1 33  ? -17.24952 22.43606  -11.21120 1.000 52.53222  ? 33  ASP A CG   1 
ATOM   481  O OD1  . ASP A 1 33  ? -17.86382 22.69944  -12.26703 1.000 52.26681  ? 33  ASP A OD1  1 
ATOM   482  O OD2  . ASP A 1 33  ? -17.79844 21.91185  -10.21952 1.000 49.11274  ? 33  ASP A OD2  1 
ATOM   483  H H    . ASP A 1 33  ? -15.66139 21.62220  -13.88720 1.000 59.01414  ? 33  ASP A H    1 
ATOM   484  H HA   . ASP A 1 33  ? -15.62002 23.56626  -12.99367 1.000 63.86328  ? 33  ASP A HA   1 
ATOM   485  H HB2  . ASP A 1 33  ? -15.32983 22.07468  -10.62338 1.000 66.77349  ? 33  ASP A HB2  1 
ATOM   486  H HB3  . ASP A 1 33  ? -15.68934 23.62247  -10.64588 1.000 66.77349  ? 33  ASP A HB3  1 
ATOM   487  N N    . ASP A 1 34  ? -13.14295 23.87088  -11.33607 1.000 47.31910  ? 34  ASP A N    1 
ATOM   488  C CA   . ASP A 1 34  ? -11.75494 24.30592  -11.23487 1.000 45.60675  ? 34  ASP A CA   1 
ATOM   489  C C    . ASP A 1 34  ? -10.87487 23.27614  -10.52836 1.000 50.96576  ? 34  ASP A C    1 
ATOM   490  O O    . ASP A 1 34  ? -9.86479  23.63716  -9.91413  1.000 48.48758  ? 34  ASP A O    1 
ATOM   491  C CB   . ASP A 1 34  ? -11.67278 25.66535  -10.53490 1.000 47.57702  ? 34  ASP A CB   1 
ATOM   492  C CG   . ASP A 1 34  ? -12.05983 25.60696  -9.06570  1.000 59.10735  ? 34  ASP A CG   1 
ATOM   493  O OD1  . ASP A 1 34  ? -12.43215 24.52249  -8.57054  1.000 59.36070  ? 34  ASP A OD1  1 
ATOM   494  O OD2  . ASP A 1 34  ? -11.98785 26.66355  -8.40210  1.000 63.07667  ? 34  ASP A OD2  1 
ATOM   495  H H    . ASP A 1 34  ? -13.59214 23.97214  -10.60972 1.000 56.77669  ? 34  ASP A H    1 
ATOM   496  H HA   . ASP A 1 34  ? -11.40212 24.41756  -12.13150 1.000 54.72187  ? 34  ASP A HA   1 
ATOM   497  H HB2  . ASP A 1 34  ? -10.76143 25.99289  -10.59024 1.000 57.08619  ? 34  ASP A HB2  1 
ATOM   498  H HB3  . ASP A 1 34  ? -12.27501 26.28373  -10.97742 1.000 57.08619  ? 34  ASP A HB3  1 
ATOM   499  N N    . VAL A 1 35  ? -11.23363 21.99549  -10.61606 1.000 52.26694  ? 35  VAL A N    1 
ATOM   500  C CA   . VAL A 1 35  ? -10.44561 20.90651  -10.05292 1.000 46.05729  ? 35  VAL A CA   1 
ATOM   501  C C    . VAL A 1 35  ? -10.11751 19.91719  -11.16277 1.000 44.77920  ? 35  VAL A C    1 
ATOM   502  O O    . VAL A 1 35  ? -10.97147 19.59845  -11.99785 1.000 44.97634  ? 35  VAL A O    1 
ATOM   503  C CB   . VAL A 1 35  ? -11.18647 20.19688  -8.90002  1.000 34.61443  ? 35  VAL A CB   1 
ATOM   504  C CG1  . VAL A 1 35  ? -10.36020 19.02306  -8.37971  1.000 41.13268  ? 35  VAL A CG1  1 
ATOM   505  C CG2  . VAL A 1 35  ? -11.49544 21.17681  -7.77950  1.000 37.50316  ? 35  VAL A CG2  1 
ATOM   506  H H    . VAL A 1 35  ? -11.95045 21.72815  -11.00886 1.000 62.71410  ? 35  VAL A H    1 
ATOM   507  H HA   . VAL A 1 35  ? -9.61526  21.26744  -9.70486  1.000 55.26252  ? 35  VAL A HA   1 
ATOM   508  H HB   . VAL A 1 35  ? -12.02840 19.84960  -9.23386  1.000 41.53109  ? 35  VAL A HB   1 
ATOM   509  H HG11 . VAL A 1 35  ? -10.30432 18.34510  -9.07119  1.000 49.35299  ? 35  VAL A HG11 1 
ATOM   510  H HG12 . VAL A 1 35  ? -9.47134  19.33842  -8.15306  1.000 49.35299  ? 35  VAL A HG12 1 
ATOM   511  H HG13 . VAL A 1 35  ? -10.79226 18.65731  -7.59202  1.000 49.35299  ? 35  VAL A HG13 1 
ATOM   512  H HG21 . VAL A 1 35  ? -11.80798 20.68297  -7.00533  1.000 44.99756  ? 35  VAL A HG21 1 
ATOM   513  H HG22 . VAL A 1 35  ? -10.68808 21.66583  -7.55608  1.000 44.99756  ? 35  VAL A HG22 1 
ATOM   514  H HG23 . VAL A 1 35  ? -12.18282 21.79229  -8.07884  1.000 44.99756  ? 35  VAL A HG23 1 
ATOM   515  N N    . VAL A 1 36  ? -8.87984  19.42963  -11.16578 1.000 40.44721  ? 36  VAL A N    1 
ATOM   516  C CA   . VAL A 1 36  ? -8.43152  18.40627  -12.10338 1.000 39.50607  ? 36  VAL A CA   1 
ATOM   517  C C    . VAL A 1 36  ? -8.08258  17.16538  -11.29402 1.000 33.06814  ? 36  VAL A C    1 
ATOM   518  O O    . VAL A 1 36  ? -7.26095  17.23033  -10.37136 1.000 40.61585  ? 36  VAL A O    1 
ATOM   519  C CB   . VAL A 1 36  ? -7.23018  18.87307  -12.94074 1.000 38.21897  ? 36  VAL A CB   1 
ATOM   520  C CG1  . VAL A 1 36  ? -6.74966  17.74675  -13.84422 1.000 33.20500  ? 36  VAL A CG1  1 
ATOM   521  C CG2  . VAL A 1 36  ? -7.59647  20.10070  -13.76218 1.000 44.16614  ? 36  VAL A CG2  1 
ATOM   522  H H    . VAL A 1 36  ? -8.26642  19.68357  -10.61913 1.000 48.53042  ? 36  VAL A H    1 
ATOM   523  H HA   . VAL A 1 36  ? -9.15425  18.18837  -12.71254 1.000 47.40105  ? 36  VAL A HA   1 
ATOM   524  H HB   . VAL A 1 36  ? -6.50479  19.11686  -12.34470 1.000 45.85654  ? 36  VAL A HB   1 
ATOM   525  H HG11 . VAL A 1 36  ? -7.45298  17.08343  -13.92327 1.000 39.83978  ? 36  VAL A HG11 1 
ATOM   526  H HG12 . VAL A 1 36  ? -6.53880  18.11104  -14.71813 1.000 39.83978  ? 36  VAL A HG12 1 
ATOM   527  H HG13 . VAL A 1 36  ? -5.95804  17.34456  -13.45372 1.000 39.83978  ? 36  VAL A HG13 1 
ATOM   528  H HG21 . VAL A 1 36  ? -6.84398  20.33963  -14.32572 1.000 52.99314  ? 36  VAL A HG21 1 
ATOM   529  H HG22 . VAL A 1 36  ? -8.36872  19.89415  -14.31159 1.000 52.99314  ? 36  VAL A HG22 1 
ATOM   530  H HG23 . VAL A 1 36  ? -7.80473  20.83258  -13.16061 1.000 52.99314  ? 36  VAL A HG23 1 
ATOM   531  N N    . TYR A 1 37  ? -8.71344  16.04568  -11.63294 1.000 32.30606  ? 37  TYR A N    1 
ATOM   532  C CA   . TYR A 1 37  ? -8.50036  14.77187  -10.96019 1.000 29.20090  ? 37  TYR A CA   1 
ATOM   533  C C    . TYR A 1 37  ? -7.63148  13.87588  -11.83403 1.000 30.58339  ? 37  TYR A C    1 
ATOM   534  O O    . TYR A 1 37  ? -7.84499  13.78696  -13.04523 1.000 32.81723  ? 37  TYR A O    1 
ATOM   535  C CB   . TYR A 1 37  ? -9.83486  14.07589  -10.68044 1.000 33.76134  ? 37  TYR A CB   1 
ATOM   536  C CG   . TYR A 1 37  ? -10.81046 14.89086  -9.86202  1.000 36.40495  ? 37  TYR A CG   1 
ATOM   537  C CD1  . TYR A 1 37  ? -11.56347 15.90243  -10.44416 1.000 33.58017  ? 37  TYR A CD1  1 
ATOM   538  C CD2  . TYR A 1 37  ? -10.99269 14.63496  -8.51018  1.000 40.48598  ? 37  TYR A CD2  1 
ATOM   539  C CE1  . TYR A 1 37  ? -12.45948 16.64310  -9.69992  1.000 34.83214  ? 37  TYR A CE1  1 
ATOM   540  C CE2  . TYR A 1 37  ? -11.88720 15.36885  -7.75960  1.000 33.14607  ? 37  TYR A CE2  1 
ATOM   541  C CZ   . TYR A 1 37  ? -12.61538 16.37281  -8.35912  1.000 35.96959  ? 37  TYR A CZ   1 
ATOM   542  O OH   . TYR A 1 37  ? -13.50678 17.10706  -7.61671  1.000 46.83066  ? 37  TYR A OH   1 
ATOM   543  H H    . TYR A 1 37  ? -9.28840  15.99845  -12.27074 1.000 38.76105  ? 37  TYR A H    1 
ATOM   544  H HA   . TYR A 1 37  ? -8.04940  14.91959  -10.11418 1.000 35.03486  ? 37  TYR A HA   1 
ATOM   545  H HB2  . TYR A 1 37  ? -10.26124 13.87408  -11.52800 1.000 40.50738  ? 37  TYR A HB2  1 
ATOM   546  H HB3  . TYR A 1 37  ? -9.65891  13.25539  -10.19390 1.000 40.50738  ? 37  TYR A HB3  1 
ATOM   547  H HD1  . TYR A 1 37  ? -11.46226 16.08379  -11.35068 1.000 40.28997  ? 37  TYR A HD1  1 
ATOM   548  H HD2  . TYR A 1 37  ? -10.50316 13.95688  -8.10341  1.000 48.57695  ? 37  TYR A HD2  1 
ATOM   549  H HE1  . TYR A 1 37  ? -12.95454 17.32020  -10.10160 1.000 41.79233  ? 37  TYR A HE1  1 
ATOM   550  H HE2  . TYR A 1 37  ? -11.99809 15.18706  -6.85431  1.000 39.76906  ? 37  TYR A HE2  1 
ATOM   551  H HH   . TYR A 1 37  ? -13.52868 16.81984  -6.82765  1.000 56.19056  ? 37  TYR A HH   1 
ATOM   552  N N    . CYS A 1 38  ? -6.65468  13.21296  -11.21916 1.000 34.69730  ? 38  CYS A N    1 
ATOM   553  C CA   . CYS A 1 38  ? -5.78929  12.29078  -11.94779 1.000 32.29819  ? 38  CYS A CA   1 
ATOM   554  C C    . CYS A 1 38  ? -5.23034  11.27166  -10.96125 1.000 35.66379  ? 38  CYS A C    1 
ATOM   555  O O    . CYS A 1 38  ? -5.29563  11.47612  -9.74582  1.000 38.98446  ? 38  CYS A O    1 
ATOM   556  C CB   . CYS A 1 38  ? -4.65222  13.03815  -12.66649 1.000 41.31724  ? 38  CYS A CB   1 
ATOM   557  S SG   . CYS A 1 38  ? -3.28823  13.61315  -11.62190 1.000 42.96870  ? 38  CYS A SG   1 
ATOM   558  H H    . CYS A 1 38  ? -6.47397  13.28078  -10.38110 1.000 41.63053  ? 38  CYS A H    1 
ATOM   559  H HA   . CYS A 1 38  ? -6.30856  11.81466  -12.61454 1.000 38.75160  ? 38  CYS A HA   1 
ATOM   560  H HB2  . CYS A 1 38  ? -4.27188  12.44273  -13.33111 1.000 49.57446  ? 38  CYS A HB2  1 
ATOM   561  H HB3  . CYS A 1 38  ? -5.03024  13.81982  -13.09891 1.000 49.57446  ? 38  CYS A HB3  1 
ATOM   562  H HG   . CYS A 1 38  ? -2.50592  14.22004  -12.29990 1.000 51.55621  ? 38  CYS A HG   1 
ATOM   563  N N    . PRO A 1 39  ? -4.69835  10.15407  -11.46062 1.000 34.07558  ? 39  PRO A N    1 
ATOM   564  C CA   . PRO A 1 39  ? -4.04444  9.19754   -10.55739 1.000 36.07481  ? 39  PRO A CA   1 
ATOM   565  C C    . PRO A 1 39  ? -2.81080  9.82253   -9.92810  1.000 41.76014  ? 39  PRO A C    1 
ATOM   566  O O    . PRO A 1 39  ? -2.09369  10.60235  -10.55956 1.000 41.91210  ? 39  PRO A O    1 
ATOM   567  C CB   . PRO A 1 39  ? -3.68436  8.02426   -11.47849 1.000 34.49689  ? 39  PRO A CB   1 
ATOM   568  C CG   . PRO A 1 39  ? -4.52675  8.21632   -12.70872 1.000 31.64274  ? 39  PRO A CG   1 
ATOM   569  C CD   . PRO A 1 39  ? -4.67428  9.69299   -12.85617 1.000 33.54458  ? 39  PRO A CD   1 
ATOM   570  H HA   . PRO A 1 39  ? -4.65171  8.88789   -9.86728  1.000 43.28355  ? 39  PRO A HA   1 
ATOM   571  H HB2  . PRO A 1 39  ? -2.73982  8.05502   -11.69712 1.000 41.39004  ? 39  PRO A HB2  1 
ATOM   572  H HB3  . PRO A 1 39  ? -3.89645  7.18492   -11.04096 1.000 41.39004  ? 39  PRO A HB3  1 
ATOM   573  H HG2  . PRO A 1 39  ? -4.07704  7.83512   -13.47901 1.000 37.96506  ? 39  PRO A HG2  1 
ATOM   574  H HG3  . PRO A 1 39  ? -5.39085  7.79304   -12.58595 1.000 37.96506  ? 39  PRO A HG3  1 
ATOM   575  H HD2  . PRO A 1 39  ? -3.92035  10.07181  -13.33469 1.000 40.24727  ? 39  PRO A HD2  1 
ATOM   576  H HD3  . PRO A 1 39  ? -5.50169  9.91623   -13.31056 1.000 40.24727  ? 39  PRO A HD3  1 
ATOM   577  N N    . ARG A 1 40  ? -2.56719  9.47254   -8.66504  1.000 38.90859  ? 40  ARG A N    1 
ATOM   578  C CA   . ARG A 1 40  ? -1.50446  10.12308  -7.91253  1.000 42.77738  ? 40  ARG A CA   1 
ATOM   579  C C    . ARG A 1 40  ? -0.11568  9.63190   -8.29865  1.000 42.20332  ? 40  ARG A C    1 
ATOM   580  O O    . ARG A 1 40  ? 0.86675   10.31855  -7.99775  1.000 35.31212  ? 40  ARG A O    1 
ATOM   581  C CB   . ARG A 1 40  ? -1.71893  9.92586   -6.40813  1.000 37.54056  ? 40  ARG A CB   1 
ATOM   582  C CG   . ARG A 1 40  ? -1.44459  8.52103   -5.91466  1.000 34.44986  ? 40  ARG A CG   1 
ATOM   583  C CD   . ARG A 1 40  ? -1.71655  8.39909   -4.42848  1.000 35.38504  ? 40  ARG A CD   1 
ATOM   584  N NE   . ARG A 1 40  ? -1.74035  7.00598   -4.00081  1.000 37.30073  ? 40  ARG A NE   1 
ATOM   585  C CZ   . ARG A 1 40  ? -1.72049  6.60452   -2.73728  1.000 33.46679  ? 40  ARG A CZ   1 
ATOM   586  N NH1  . ARG A 1 40  ? -1.66971  7.46754   -1.73666  1.000 42.21150  ? 40  ARG A NH1  1 
ATOM   587  N NH2  . ARG A 1 40  ? -1.74058  5.30248   -2.47163  1.000 33.92476  ? 40  ARG A NH2  1 
ATOM   588  H H    . ARG A 1 40  ? -2.99886  8.86928   -8.22990  1.000 46.68407  ? 40  ARG A H    1 
ATOM   589  H HA   . ARG A 1 40  ? -1.54197  11.07483  -8.09604  1.000 51.32663  ? 40  ARG A HA   1 
ATOM   590  H HB2  . ARG A 1 40  ? -1.12518  10.52569  -5.93004  1.000 45.04244  ? 40  ARG A HB2  1 
ATOM   591  H HB3  . ARG A 1 40  ? -2.64229  10.13547  -6.19748  1.000 45.04244  ? 40  ARG A HB3  1 
ATOM   592  H HG2  . ARG A 1 40  ? -2.02005  7.89650   -6.38340  1.000 41.33360  ? 40  ARG A HG2  1 
ATOM   593  H HG3  . ARG A 1 40  ? -0.51401  8.29902   -6.07478  1.000 41.33360  ? 40  ARG A HG3  1 
ATOM   594  H HD2  . ARG A 1 40  ? -1.01783  8.85729   -3.93579  1.000 42.45582  ? 40  ARG A HD2  1 
ATOM   595  H HD3  . ARG A 1 40  ? -2.57890  8.79468   -4.22659  1.000 42.45582  ? 40  ARG A HD3  1 
ATOM   596  H HE   . ARG A 1 40  ? -1.76934  6.40120   -4.61156  1.000 44.75465  ? 40  ARG A HE   1 
ATOM   597  H HH11 . ARG A 1 40  ? -1.64870  8.31204   -1.89783  1.000 50.64758  ? 40  ARG A HH11 1 
ATOM   598  H HH12 . ARG A 1 40  ? -1.65770  7.18431   -0.92473  1.000 50.64758  ? 40  ARG A HH12 1 
ATOM   599  H HH21 . ARG A 1 40  ? -1.76613  4.73265   -3.11525  1.000 40.70348  ? 40  ARG A HH21 1 
ATOM   600  H HH22 . ARG A 1 40  ? -1.72803  5.02976   -1.65611  1.000 40.70348  ? 40  ARG A HH22 1 
ATOM   601  N N    . HIS A 1 41  ? 0.00118   8.47665   -8.95766  1.000 39.21989  ? 41  HIS A N    1 
ATOM   602  C CA   . HIS A 1 41  ? 1.32020   7.99388   -9.35144  1.000 39.61236  ? 41  HIS A CA   1 
ATOM   603  C C    . HIS A 1 41  ? 1.87227   8.74468   -10.55852 1.000 40.92791  ? 41  HIS A C    1 
ATOM   604  O O    . HIS A 1 41  ? 2.88910   8.32778   -11.12181 1.000 40.88051  ? 41  HIS A O    1 
ATOM   605  C CB   . HIS A 1 41  ? 1.29616   6.47726   -9.60221  1.000 36.85748  ? 41  HIS A CB   1 
ATOM   606  C CG   . HIS A 1 41  ? 0.61514   6.05809   -10.86885 1.000 43.54154  ? 41  HIS A CG   1 
ATOM   607  N ND1  . HIS A 1 41  ? -0.59121  5.39109   -10.87673 1.000 46.52405  ? 41  HIS A ND1  1 
ATOM   608  C CD2  . HIS A 1 41  ? 0.99530   6.16054   -12.16479 1.000 38.51229  ? 41  HIS A CD2  1 
ATOM   609  C CE1  . HIS A 1 41  ? -0.93899  5.12708   -12.12362 1.000 43.14241  ? 41  HIS A CE1  1 
ATOM   610  N NE2  . HIS A 1 41  ? 0.00432   5.58766   -12.92512 1.000 40.68305  ? 41  HIS A NE2  1 
ATOM   611  H H    . HIS A 1 41  ? -0.65560  7.96857   -9.18150  1.000 47.05763  ? 41  HIS A H    1 
ATOM   612  H HA   . HIS A 1 41  ? 1.93695   8.13243   -8.61570  1.000 47.52861  ? 41  HIS A HA   1 
ATOM   613  H HB2  . HIS A 1 41  ? 2.21118   6.15806   -9.64422  1.000 44.22274  ? 41  HIS A HB2  1 
ATOM   614  H HB3  . HIS A 1 41  ? 0.82967   6.05130   -8.86611  1.000 44.22274  ? 41  HIS A HB3  1 
ATOM   615  H HD2  . HIS A 1 41  ? 1.78020   6.54641   -12.48093 1.000 46.20851  ? 41  HIS A HD2  1 
ATOM   616  H HE1  . HIS A 1 41  ? -1.71566  4.69119   -12.39135 1.000 51.76466  ? 41  HIS A HE1  1 
ATOM   617  H HE2  . HIS A 1 41  ? -0.00080  5.53722   -13.78363 1.000 48.81343  ? 41  HIS A HE2  1 
ATOM   618  N N    . VAL A 1 42  ? 1.23562   9.85408   -10.94603 1.000 44.62680  ? 42  VAL A N    1 
ATOM   619  C CA   . VAL A 1 42  ? 1.84727   10.77456  -11.89963 1.000 45.97275  ? 42  VAL A CA   1 
ATOM   620  C C    . VAL A 1 42  ? 3.11184   11.38762  -11.31290 1.000 44.46655  ? 42  VAL A C    1 
ATOM   621  O O    . VAL A 1 42  ? 4.03013   11.76652  -12.04975 1.000 45.64312  ? 42  VAL A O    1 
ATOM   622  C CB   . VAL A 1 42  ? 0.83359   11.86285  -12.31368 1.000 44.92771  ? 42  VAL A CB   1 
ATOM   623  C CG1  . VAL A 1 42  ? 0.49421   12.77655  -11.13305 1.000 42.39413  ? 42  VAL A CG1  1 
ATOM   624  C CG2  . VAL A 1 42  ? 1.36606   12.66880  -13.48956 1.000 46.56669  ? 42  VAL A CG2  1 
ATOM   625  H H    . VAL A 1 42  ? 0.45582   10.09260  -10.67284 1.000 53.54593  ? 42  VAL A H    1 
ATOM   626  H HA   . VAL A 1 42  ? 2.09515   10.27780  -12.69504 1.000 55.16107  ? 42  VAL A HA   1 
ATOM   627  H HB   . VAL A 1 42  ? 0.01214   11.42921  -12.59310 1.000 53.90703  ? 42  VAL A HB   1 
ATOM   628  H HG11 . VAL A 1 42  ? 1.31846   13.07945  -10.72102 1.000 50.86673  ? 42  VAL A HG11 1 
ATOM   629  H HG12 . VAL A 1 42  ? -0.01225  13.53737  -11.45792 1.000 50.86673  ? 42  VAL A HG12 1 
ATOM   630  H HG13 . VAL A 1 42  ? -0.03358  12.27823  -10.48961 1.000 50.86673  ? 42  VAL A HG13 1 
ATOM   631  H HG21 . VAL A 1 42  ? 0.65285   13.22511  -13.83991 1.000 55.87379  ? 42  VAL A HG21 1 
ATOM   632  H HG22 . VAL A 1 42  ? 2.09999   13.22496  -13.18471 1.000 55.87379  ? 42  VAL A HG22 1 
ATOM   633  H HG23 . VAL A 1 42  ? 1.67683   12.05809  -14.17611 1.000 55.87379  ? 42  VAL A HG23 1 
ATOM   634  N N    . ILE A 1 43  ? 3.18299   11.49708  -9.98042  1.000 41.19124  ? 43  ILE A N    1 
ATOM   635  C CA   . ILE A 1 43  ? 4.35433   12.07226  -9.32213  1.000 58.59048  ? 43  ILE A CA   1 
ATOM   636  C C    . ILE A 1 43  ? 5.48101   11.06800  -9.16479  1.000 54.15332  ? 43  ILE A C    1 
ATOM   637  O O    . ILE A 1 43  ? 6.50849   11.39384  -8.55553  1.000 55.71534  ? 43  ILE A O    1 
ATOM   638  C CB   . ILE A 1 43  ? 3.97544   12.63398  -7.93552  1.000 46.31560  ? 43  ILE A CB   1 
ATOM   639  C CG1  . ILE A 1 43  ? 3.75114   11.49596  -6.93549  1.000 44.03700  ? 43  ILE A CG1  1 
ATOM   640  C CG2  . ILE A 1 43  ? 2.72797   13.49036  -8.03562  1.000 50.60557  ? 43  ILE A CG2  1 
ATOM   641  C CD1  . ILE A 1 43  ? 3.17086   11.95194  -5.61143  1.000 51.39267  ? 43  ILE A CD1  1 
ATOM   642  H H    . ILE A 1 43  ? 2.56476   11.24478  -9.43845  1.000 49.42326  ? 43  ILE A H    1 
ATOM   643  H HA   . ILE A 1 43  ? 4.68297   12.80166  -9.87065  1.000 70.30234  ? 43  ILE A HA   1 
ATOM   644  H HB   . ILE A 1 43  ? 4.71120   13.18263  -7.62159  1.000 55.57249  ? 43  ILE A HB   1 
ATOM   645  H HG12 . ILE A 1 43  ? 3.13445   10.85612  -7.32433  1.000 52.83817  ? 43  ILE A HG12 1 
ATOM   646  H HG13 . ILE A 1 43  ? 4.60249   11.06801  -6.75392  1.000 52.83817  ? 43  ILE A HG13 1 
ATOM   647  H HG21 . ILE A 1 43  ? 2.72632   14.13218  -7.30833  1.000 60.72046  ? 43  ILE A HG21 1 
ATOM   648  H HG22 . ILE A 1 43  ? 2.73150   13.95519  -8.88699  1.000 60.72046  ? 43  ILE A HG22 1 
ATOM   649  H HG23 . ILE A 1 43  ? 1.94672   12.91872  -7.97410  1.000 60.72046  ? 43  ILE A HG23 1 
ATOM   650  H HD11 . ILE A 1 43  ? 3.63264   12.75512  -5.32410  1.000 61.66497  ? 43  ILE A HD11 1 
ATOM   651  H HD12 . ILE A 1 43  ? 2.22591   12.13742  -5.72789  1.000 61.66497  ? 43  ILE A HD12 1 
ATOM   652  H HD13 . ILE A 1 43  ? 3.29135   11.24827  -4.95475  1.000 61.66497  ? 43  ILE A HD13 1 
ATOM   653  N N    . CYS A 1 44  ? 5.32114   9.85770   -9.68949  1.000 52.05950  ? 44  CYS A N    1 
ATOM   654  C CA   . CYS A 1 44  ? 6.27063   8.77813   -9.47274  1.000 51.01655  ? 44  CYS A CA   1 
ATOM   655  C C    . CYS A 1 44  ? 7.23971   8.65026   -10.64003 1.000 57.78438  ? 44  CYS A C    1 
ATOM   656  O O    . CYS A 1 44  ? 6.87507   8.87737   -11.79779 1.000 57.94349  ? 44  CYS A O    1 
ATOM   657  C CB   . CYS A 1 44  ? 5.54156   7.44515   -9.27708  1.000 58.69248  ? 44  CYS A CB   1 
ATOM   658  S SG   . CYS A 1 44  ? 4.86361   7.17930   -7.62830  1.000 54.80970  ? 44  CYS A SG   1 
ATOM   659  H H    . CYS A 1 44  ? 4.65481   9.63489   -10.18543 1.000 62.46517  ? 44  CYS A H    1 
ATOM   660  H HA   . CYS A 1 44  ? 6.78717   8.98094   -8.67715  1.000 61.21363  ? 44  CYS A HA   1 
ATOM   661  H HB2  . CYS A 1 44  ? 4.80316   7.40467   -9.90479  1.000 70.42475  ? 44  CYS A HB2  1 
ATOM   662  H HB3  . CYS A 1 44  ? 6.16693   6.72498   -9.45362  1.000 70.42475  ? 44  CYS A HB3  1 
ATOM   663  H HG   . CYS A 1 44  ? 4.35779   6.09200   -7.58452  1.000 65.76542  ? 44  CYS A HG   1 
ATOM   664  N N    . THR A 1 45  ? 8.47863   8.29054   -10.32192 1.000 56.88601  ? 45  THR A N    1 
ATOM   665  C CA   . THR A 1 45  ? 9.42272   7.79953   -11.31167 1.000 63.90539  ? 45  THR A CA   1 
ATOM   666  C C    . THR A 1 45  ? 9.28573   6.28282   -11.41921 1.000 64.48689  ? 45  THR A C    1 
ATOM   667  O O    . THR A 1 45  ? 8.73108   5.62226   -10.53681 1.000 63.37973  ? 45  THR A O    1 
ATOM   668  C CB   . THR A 1 45  ? 10.85875  8.17757   -10.94164 1.000 62.26891  ? 45  THR A CB   1 
ATOM   669  O OG1  . THR A 1 45  ? 11.21911  7.56527   -9.69715  1.000 61.36141  ? 45  THR A OG1  1 
ATOM   670  C CG2  . THR A 1 45  ? 11.00423  9.69030   -10.81801 1.000 59.59674  ? 45  THR A CG2  1 
ATOM   671  H H    . THR A 1 45  ? 8.79958   8.32317   -9.52472  1.000 68.25699  ? 45  THR A H    1 
ATOM   672  H HA   . THR A 1 45  ? 9.23718   8.20100   -12.17497 1.000 76.68024  ? 45  THR A HA   1 
ATOM   673  H HB   . THR A 1 45  ? 11.45808  7.86787   -11.63862 1.000 74.71647  ? 45  THR A HB   1 
ATOM   674  H HG1  . THR A 1 45  ? 11.96151  7.85943   -9.43657  1.000 73.62746  ? 45  THR A HG1  1 
ATOM   675  H HG21 . THR A 1 45  ? 10.53757  10.00501  -10.02801 1.000 71.50985  ? 45  THR A HG21 1 
ATOM   676  H HG22 . THR A 1 45  ? 11.94172  9.92862   -10.74569 1.000 71.50985  ? 45  THR A HG22 1 
ATOM   677  H HG23 . THR A 1 45  ? 10.62838  10.12472  -11.59962 1.000 71.50985  ? 45  THR A HG23 1 
ATOM   678  N N    . SER A 1 46  ? 9.79041   5.73080   -12.52410 1.000 58.24570  ? 46  SER A N    1 
ATOM   679  C CA   . SER A 1 46  ? 9.70634   4.28666   -12.71507 1.000 69.10898  ? 46  SER A CA   1 
ATOM   680  C C    . SER A 1 46  ? 10.38720  3.52340   -11.58637 1.000 68.07005  ? 46  SER A C    1 
ATOM   681  O O    . SER A 1 46  ? 10.05285  2.35674   -11.34997 1.000 67.85636  ? 46  SER A O    1 
ATOM   682  C CB   . SER A 1 46  ? 10.31270  3.89700   -14.06350 1.000 69.11773  ? 46  SER A CB   1 
ATOM   683  O OG   . SER A 1 46  ? 9.49777   4.35569   -15.13025 1.000 70.33592  ? 46  SER A OG   1 
ATOM   684  H H    . SER A 1 46  ? 10.17640  6.16073   -13.16111 1.000 69.88861  ? 46  SER A H    1 
ATOM   685  H HA   . SER A 1 46  ? 8.77250   4.02466   -12.72915 1.000 82.92455  ? 46  SER A HA   1 
ATOM   686  H HB2  . SER A 1 46  ? 11.19252  4.29771   -14.14249 1.000 82.93504  ? 46  SER A HB2  1 
ATOM   687  H HB3  . SER A 1 46  ? 10.38270  2.93072   -14.11163 1.000 82.93504  ? 46  SER A HB3  1 
ATOM   688  H HG   . SER A 1 46  ? 9.41198   5.19022   -15.08794 1.000 84.39688  ? 46  SER A HG   1 
ATOM   689  N N    . GLU A 1 47  ? 11.32983  4.15230   -10.88322 1.000 58.90232  ? 47  GLU A N    1 
ATOM   690  C CA   . GLU A 1 47  ? 11.90110  3.53723   -9.69185  1.000 61.72542  ? 47  GLU A CA   1 
ATOM   691  C C    . GLU A 1 47  ? 10.93193  3.61773   -8.51673  1.000 65.98125  ? 47  GLU A C    1 
ATOM   692  O O    . GLU A 1 47  ? 10.79371  2.65694   -7.75100  1.000 67.66318  ? 47  GLU A O    1 
ATOM   693  C CB   . GLU A 1 47  ? 13.22558  4.21858   -9.34470  1.000 60.41112  ? 47  GLU A CB   1 
ATOM   694  C CG   . GLU A 1 47  ? 14.08784  3.45662   -8.35741  1.000 67.62589  ? 47  GLU A CG   1 
ATOM   695  C CD   . GLU A 1 47  ? 15.53663  3.37756   -8.80140  1.000 76.45379  ? 47  GLU A CD   1 
ATOM   696  O OE1  . GLU A 1 47  ? 16.06958  4.39936   -9.28550  1.000 72.75583  ? 47  GLU A OE1  1 
ATOM   697  O OE2  . GLU A 1 47  ? 16.13689  2.28883   -8.67899  1.000 79.75205  ? 47  GLU A OE2  1 
ATOM   698  H H    . GLU A 1 47  ? 11.65083  4.92693   -11.07430 1.000 70.67655  ? 47  GLU A H    1 
ATOM   699  H HA   . GLU A 1 47  ? 12.08411  2.60109   -9.86811  1.000 74.06427  ? 47  GLU A HA   1 
ATOM   700  H HB2  . GLU A 1 47  ? 13.74000  4.32641   -10.15995 1.000 72.48712  ? 47  GLU A HB2  1 
ATOM   701  H HB3  . GLU A 1 47  ? 13.03353  5.08646   -8.95636  1.000 72.48712  ? 47  GLU A HB3  1 
ATOM   702  H HG2  . GLU A 1 47  ? 14.05936  3.90525   -7.49786  1.000 81.14485  ? 47  GLU A HG2  1 
ATOM   703  H HG3  . GLU A 1 47  ? 13.74861  2.55200   -8.27088  1.000 81.14485  ? 47  GLU A HG3  1 
ATOM   704  N N    . ASP A 1 48  ? 10.24211  4.75305   -8.37418  1.000 53.83552  ? 48  ASP A N    1 
ATOM   705  C CA   . ASP A 1 48  ? 9.36085   4.95341   -7.22841  1.000 62.77025  ? 48  ASP A CA   1 
ATOM   706  C C    . ASP A 1 48  ? 8.25871   3.90236   -7.17019  1.000 61.98847  ? 48  ASP A C    1 
ATOM   707  O O    . ASP A 1 48  ? 7.84472   3.49177   -6.07772  1.000 54.05389  ? 48  ASP A O    1 
ATOM   708  C CB   . ASP A 1 48  ? 8.73688   6.35178   -7.28862  1.000 62.07338  ? 48  ASP A CB   1 
ATOM   709  C CG   . ASP A 1 48  ? 9.74473   7.46008   -7.04248  1.000 66.61965  ? 48  ASP A CG   1 
ATOM   710  O OD1  . ASP A 1 48  ? 10.58121  7.31992   -6.12443  1.000 70.01444  ? 48  ASP A OD1  1 
ATOM   711  O OD2  . ASP A 1 48  ? 9.69402   8.47653   -7.76827  1.000 58.60475  ? 48  ASP A OD2  1 
ATOM   712  H H    . ASP A 1 48  ? 10.26780  5.41511   -8.92247  1.000 64.59639  ? 48  ASP A H    1 
ATOM   713  H HA   . ASP A 1 48  ? 9.88972   4.88333   -6.41830  1.000 75.31807  ? 48  ASP A HA   1 
ATOM   714  H HB2  . ASP A 1 48  ? 8.35156   6.48768   -8.16837  1.000 74.48182  ? 48  ASP A HB2  1 
ATOM   715  H HB3  . ASP A 1 48  ? 8.04680   6.41878   -6.61023  1.000 74.48182  ? 48  ASP A HB3  1 
ATOM   716  N N    . MET A 1 49  ? 7.77164   3.45757   -8.32955  1.000 64.92144  ? 49  MET A N    1 
ATOM   717  C CA   . MET A 1 49  ? 6.55244   2.65818   -8.37767  1.000 60.95312  ? 49  MET A CA   1 
ATOM   718  C C    . MET A 1 49  ? 6.70031   1.30090   -7.70351  1.000 48.60530  ? 49  MET A C    1 
ATOM   719  O O    . MET A 1 49  ? 5.69008   0.71316   -7.30239  1.000 49.22404  ? 49  MET A O    1 
ATOM   720  C CB   . MET A 1 49  ? 6.11434   2.47328   -9.83287  1.000 57.32009  ? 49  MET A CB   1 
ATOM   721  C CG   . MET A 1 49  ? 5.43934   3.70500   -10.41320 1.000 62.77195  ? 49  MET A CG   1 
ATOM   722  S SD   . MET A 1 49  ? 5.36714   3.71296   -12.21086 1.000 76.52370  ? 49  MET A SD   1 
ATOM   723  C CE   . MET A 1 49  ? 4.69944   5.34865   -12.51239 1.000 61.04919  ? 49  MET A CE   1 
ATOM   724  H H    . MET A 1 49  ? 8.12797   3.60508   -9.09823  1.000 77.89950  ? 49  MET A H    1 
ATOM   725  H HA   . MET A 1 49  ? 5.85529   3.14491   -7.91079  1.000 73.13751  ? 49  MET A HA   1 
ATOM   726  H HB2  . MET A 1 49  ? 6.89531   2.27751   -10.37384 1.000 68.77788  ? 49  MET A HB2  1 
ATOM   727  H HB3  . MET A 1 49  ? 5.48472   1.73693   -9.88049  1.000 68.77788  ? 49  MET A HB3  1 
ATOM   728  H HG2  . MET A 1 49  ? 4.52919   3.74815   -10.08053 1.000 75.32011  ? 49  MET A HG2  1 
ATOM   729  H HG3  . MET A 1 49  ? 5.93243   4.49214   -10.13360 1.000 75.32011  ? 49  MET A HG3  1 
ATOM   730  H HE1  . MET A 1 49  ? 5.41244   6.00105   -12.42927 1.000 73.25280  ? 49  MET A HE1  1 
ATOM   731  H HE2  . MET A 1 49  ? 4.32721   5.37770   -13.40765 1.000 73.25280  ? 49  MET A HE2  1 
ATOM   732  H HE3  . MET A 1 49  ? 4.00572   5.53183   -11.85962 1.000 73.25280  ? 49  MET A HE3  1 
ATOM   733  N N    . LEU A 1 50  ? 7.92306   0.78767   -7.56331  1.000 47.60951  ? 50  LEU A N    1 
ATOM   734  C CA   . LEU A 1 50  ? 8.08887   -0.52591  -6.94922  1.000 58.91889  ? 50  LEU A CA   1 
ATOM   735  C C    . LEU A 1 50  ? 7.65688   -0.52480  -5.48724  1.000 57.81234  ? 50  LEU A C    1 
ATOM   736  O O    . LEU A 1 50  ? 7.25696   -1.56910  -4.96061  1.000 59.40994  ? 50  LEU A O    1 
ATOM   737  C CB   . LEU A 1 50  ? 9.53942   -0.99090  -7.08315  1.000 55.76273  ? 50  LEU A CB   1 
ATOM   738  C CG   . LEU A 1 50  ? 9.88319   -1.70561  -8.39628  1.000 62.63992  ? 50  LEU A CG   1 
ATOM   739  C CD1  . LEU A 1 50  ? 9.10116   -3.01063  -8.53007  1.000 41.97447  ? 50  LEU A CD1  1 
ATOM   740  C CD2  . LEU A 1 50  ? 9.62506   -0.81081  -9.60301  1.000 55.92041  ? 50  LEU A CD2  1 
ATOM   741  H H    . LEU A 1 50  ? 8.65313   1.17003   -7.80909  1.000 57.12519  ? 50  LEU A H    1 
ATOM   742  H HA   . LEU A 1 50  ? 7.52919   -1.16248  -7.42086  1.000 70.69644  ? 50  LEU A HA   1 
ATOM   743  H HB2  . LEU A 1 50  ? 10.11589  -0.21360  -7.01687  1.000 66.90905  ? 50  LEU A HB2  1 
ATOM   744  H HB3  . LEU A 1 50  ? 9.72971   -1.60776  -6.35915  1.000 66.90905  ? 50  LEU A HB3  1 
ATOM   745  H HG   . LEU A 1 50  ? 10.82965  -1.91746  -8.38111  1.000 75.16167  ? 50  LEU A HG   1 
ATOM   746  H HD11 . LEU A 1 50  ? 8.21515   -2.81416  -8.87252  1.000 50.36313  ? 50  LEU A HD11 1 
ATOM   747  H HD12 . LEU A 1 50  ? 9.56993   -3.59827  -9.14312  1.000 50.36313  ? 50  LEU A HD12 1 
ATOM   748  H HD13 . LEU A 1 50  ? 9.03330   -3.42899  -7.65756  1.000 50.36313  ? 50  LEU A HD13 1 
ATOM   749  H HD21 . LEU A 1 50  ? 10.11291  0.01996   -9.49025  1.000 67.09827  ? 50  LEU A HD21 1 
ATOM   750  H HD22 . LEU A 1 50  ? 9.92781   -1.26605  -10.40425 1.000 67.09827  ? 50  LEU A HD22 1 
ATOM   751  H HD23 . LEU A 1 50  ? 8.67401   -0.63018  -9.66454  1.000 67.09827  ? 50  LEU A HD23 1 
ATOM   752  N N    . ASN A 1 51  ? 7.72000   0.62654   -4.81966  1.000 60.05459  ? 51  ASN A N    1 
ATOM   753  C CA   . ASN A 1 51  ? 7.27573   0.74534   -3.43520  1.000 60.31954  ? 51  ASN A CA   1 
ATOM   754  C C    . ASN A 1 51  ? 7.22259   2.22061   -3.05504  1.000 56.52970  ? 51  ASN A C    1 
ATOM   755  O O    . ASN A 1 51  ? 8.10528   2.70989   -2.33787  1.000 51.56796  ? 51  ASN A O    1 
ATOM   756  C CB   . ASN A 1 51  ? 8.20736   -0.02040  -2.49542  1.000 61.92773  ? 51  ASN A CB   1 
ATOM   757  C CG   . ASN A 1 51  ? 7.65650   -0.12206  -1.08992  1.000 62.00130  ? 51  ASN A CG   1 
ATOM   758  O OD1  . ASN A 1 51  ? 6.45148   0.01328   -0.87351  1.000 65.23222  ? 51  ASN A OD1  1 
ATOM   759  N ND2  . ASN A 1 51  ? 8.53656   -0.36286  -0.12399  1.000 63.00005  ? 51  ASN A ND2  1 
ATOM   760  H H    . ASN A 1 51  ? 8.01995   1.36100   -5.15164  1.000 72.05928  ? 51  ASN A H    1 
ATOM   761  H HA   . ASN A 1 51  ? 6.38855   0.36462   -3.34113  1.000 72.37722  ? 51  ASN A HA   1 
ATOM   762  H HB2  . ASN A 1 51  ? 8.33152   -0.92017  -2.83585  1.000 74.30705  ? 51  ASN A HB2  1 
ATOM   763  H HB3  . ASN A 1 51  ? 9.06082   0.43850   -2.45175  1.000 74.30705  ? 51  ASN A HB3  1 
ATOM   764  H HD21 . ASN A 1 51  ? 8.27230   -0.42938  0.69170   1.000 75.59383  ? 51  ASN A HD21 1 
ATOM   765  H HD22 . ASN A 1 51  ? 9.37042   -0.45218  -0.31448  1.000 75.59383  ? 51  ASN A HD22 1 
ATOM   766  N N    . PRO A 1 52  ? 6.20826   2.95689   -3.50014  1.000 53.78853  ? 52  PRO A N    1 
ATOM   767  C CA   . PRO A 1 52  ? 6.22925   4.41200   -3.33844  1.000 52.62874  ? 52  PRO A CA   1 
ATOM   768  C C    . PRO A 1 52  ? 5.78350   4.86334   -1.95787  1.000 46.08191  ? 52  PRO A C    1 
ATOM   769  O O    . PRO A 1 52  ? 4.97193   4.21833   -1.28990  1.000 43.96867  ? 52  PRO A O    1 
ATOM   770  C CB   . PRO A 1 52  ? 5.24504   4.90281   -4.41271  1.000 53.79525  ? 52  PRO A CB   1 
ATOM   771  C CG   . PRO A 1 52  ? 4.51210   3.64932   -4.92896  1.000 46.64838  ? 52  PRO A CG   1 
ATOM   772  C CD   . PRO A 1 52  ? 4.93439   2.49242   -4.07347  1.000 48.15691  ? 52  PRO A CD   1 
ATOM   773  H HA   . PRO A 1 52  ? 7.11976   4.75364   -3.51505  1.000 63.14825  ? 52  PRO A HA   1 
ATOM   774  H HB2  . PRO A 1 52  ? 4.61770   5.52834   -4.01766  1.000 64.54807  ? 52  PRO A HB2  1 
ATOM   775  H HB3  . PRO A 1 52  ? 5.73518   5.33329   -5.13058  1.000 64.54807  ? 52  PRO A HB3  1 
ATOM   776  H HG2  . PRO A 1 52  ? 3.55447   3.78755   -4.86014  1.000 55.97183  ? 52  PRO A HG2  1 
ATOM   777  H HG3  . PRO A 1 52  ? 4.75904   3.49247   -5.85379  1.000 55.97183  ? 52  PRO A HG3  1 
ATOM   778  H HD2  . PRO A 1 52  ? 4.28239   2.32040   -3.37619  1.000 57.78207  ? 52  PRO A HD2  1 
ATOM   779  H HD3  . PRO A 1 52  ? 5.06555   1.69449   -4.60921  1.000 57.78207  ? 52  PRO A HD3  1 
ATOM   780  N N    . ASN A 1 53  ? 6.33744   5.99775   -1.53952  1.000 40.10372  ? 53  ASN A N    1 
ATOM   781  C CA   . ASN A 1 53  ? 5.86495   6.74793   -0.37806  1.000 46.41660  ? 53  ASN A CA   1 
ATOM   782  C C    . ASN A 1 53  ? 5.21867   8.01302   -0.94186  1.000 43.91313  ? 53  ASN A C    1 
ATOM   783  O O    . ASN A 1 53  ? 5.87056   9.04809   -1.09496  1.000 41.68442  ? 53  ASN A O    1 
ATOM   784  C CB   . ASN A 1 53  ? 6.99665   7.06968   0.59774   1.000 46.67638  ? 53  ASN A CB   1 
ATOM   785  C CG   . ASN A 1 53  ? 6.49973   7.75612   1.85681   1.000 49.18114  ? 53  ASN A CG   1 
ATOM   786  O OD1  . ASN A 1 53  ? 5.38718   8.27959   1.89223   1.000 48.64847  ? 53  ASN A OD1  1 
ATOM   787  N ND2  . ASN A 1 53  ? 7.32393   7.75854   2.89648   1.000 61.95702  ? 53  ASN A ND2  1 
ATOM   788  H H    . ASN A 1 53  ? 7.01197   6.36573   -1.92579  1.000 48.11824  ? 53  ASN A H    1 
ATOM   789  H HA   . ASN A 1 53  ? 5.21008   6.22753   0.11309   1.000 55.69369  ? 53  ASN A HA   1 
ATOM   790  H HB2  . ASN A 1 53  ? 7.43537   6.24458   0.85779   1.000 56.00542  ? 53  ASN A HB2  1 
ATOM   791  H HB3  . ASN A 1 53  ? 7.63163   7.66042   0.16333   1.000 56.00542  ? 53  ASN A HB3  1 
ATOM   792  H HD21 . ASN A 1 53  ? 7.08684   8.13533   3.63229   1.000 74.34219  ? 53  ASN A HD21 1 
ATOM   793  H HD22 . ASN A 1 53  ? 8.09527   7.38331   2.83459   1.000 74.34219  ? 53  ASN A HD22 1 
ATOM   794  N N    . TYR A 1 54  ? 3.92677   7.91615   -1.26313  1.000 45.23913  ? 54  TYR A N    1 
ATOM   795  C CA   . TYR A 1 54  ? 3.25015   9.02302   -1.93112  1.000 45.14019  ? 54  TYR A CA   1 
ATOM   796  C C    . TYR A 1 54  ? 3.24697   10.27576  -1.06473  1.000 45.42441  ? 54  TYR A C    1 
ATOM   797  O O    . TYR A 1 54  ? 3.50932   11.37867  -1.55827  1.000 48.89145  ? 54  TYR A O    1 
ATOM   798  C CB   . TYR A 1 54  ? 1.82509   8.61419   -2.30755  1.000 41.59709  ? 54  TYR A CB   1 
ATOM   799  C CG   . TYR A 1 54  ? 1.77025   7.63922   -3.46645  1.000 42.38127  ? 54  TYR A CG   1 
ATOM   800  C CD1  . TYR A 1 54  ? 2.08778   8.04564   -4.75687  1.000 38.40447  ? 54  TYR A CD1  1 
ATOM   801  C CD2  . TYR A 1 54  ? 1.40468   6.31301   -3.27144  1.000 41.24370  ? 54  TYR A CD2  1 
ATOM   802  C CE1  . TYR A 1 54  ? 2.04441   7.15674   -5.81937  1.000 37.41277  ? 54  TYR A CE1  1 
ATOM   803  C CE2  . TYR A 1 54  ? 1.35354   5.41858   -4.32925  1.000 36.01492  ? 54  TYR A CE2  1 
ATOM   804  C CZ   . TYR A 1 54  ? 1.67297   5.84468   -5.59958  1.000 40.60079  ? 54  TYR A CZ   1 
ATOM   805  O OH   . TYR A 1 54  ? 1.62379   4.95269   -6.64976  1.000 35.67397  ? 54  TYR A OH   1 
ATOM   806  H H    . TYR A 1 54  ? 3.42951   7.23196   -1.10751  1.000 54.28073  ? 54  TYR A H    1 
ATOM   807  H HA   . TYR A 1 54  ? 3.72551   9.23335   -2.75009  1.000 54.16199  ? 54  TYR A HA   1 
ATOM   808  H HB2  . TYR A 1 54  ? 1.40707   8.19093   -1.54138  1.000 49.91028  ? 54  TYR A HB2  1 
ATOM   809  H HB3  . TYR A 1 54  ? 1.32743   9.40731   -2.56094  1.000 49.91028  ? 54  TYR A HB3  1 
ATOM   810  H HD1  . TYR A 1 54  ? 2.33362   8.92936   -4.91016  1.000 46.07914  ? 54  TYR A HD1  1 
ATOM   811  H HD2  . TYR A 1 54  ? 1.19030   6.01991   -2.41526  1.000 49.48622  ? 54  TYR A HD2  1 
ATOM   812  H HE1  . TYR A 1 54  ? 2.26446   7.44247   -6.67660  1.000 44.88909  ? 54  TYR A HE1  1 
ATOM   813  H HE2  . TYR A 1 54  ? 1.10465   4.53471   -4.18190  1.000 43.21168  ? 54  TYR A HE2  1 
ATOM   814  H HH   . TYR A 1 54  ? 1.04743   4.36094   -6.49734  1.000 42.80253  ? 54  TYR A HH   1 
ATOM   815  N N    . GLU A 1 55  ? 2.96240   10.12827  0.23049   1.000 46.94029  ? 55  GLU A N    1 
ATOM   816  C CA   . GLU A 1 55  ? 2.95387   11.28407  1.12141   1.000 47.91884  ? 55  GLU A CA   1 
ATOM   817  C C    . GLU A 1 55  ? 4.27438   12.04581  1.04197   1.000 51.09564  ? 55  GLU A C    1 
ATOM   818  O O    . GLU A 1 55  ? 4.29230   13.27695  0.92594   1.000 52.60922  ? 55  GLU A O    1 
ATOM   819  C CB   . GLU A 1 55  ? 2.66899   10.83361  2.55686   1.000 52.92378  ? 55  GLU A CB   1 
ATOM   820  C CG   . GLU A 1 55  ? 1.21661   10.43156  2.82473   1.000 58.79564  ? 55  GLU A CG   1 
ATOM   821  C CD   . GLU A 1 55  ? 0.83314   9.09017   2.20748   1.000 74.27660  ? 55  GLU A CD   1 
ATOM   822  O OE1  . GLU A 1 55  ? 1.74096   8.31067   1.84520   1.000 71.17054  ? 55  GLU A OE1  1 
ATOM   823  O OE2  . GLU A 1 55  ? -0.38169  8.81483   2.08685   1.000 67.37884  ? 55  GLU A OE2  1 
ATOM   824  H H    . GLU A 1 55  ? 2.77388   9.38051   0.61117   1.000 56.32212  ? 55  GLU A H    1 
ATOM   825  H HA   . GLU A 1 55  ? 2.24354   11.88687  0.85129   1.000 57.49638  ? 55  GLU A HA   1 
ATOM   826  H HB2  . GLU A 1 55  ? 3.22620   10.06470  2.75483   1.000 63.50231  ? 55  GLU A HB2  1 
ATOM   827  H HB3  . GLU A 1 55  ? 2.88553   11.56373  3.15764   1.000 63.50231  ? 55  GLU A HB3  1 
ATOM   828  H HG2  . GLU A 1 55  ? 1.08114   10.36686  3.78304   1.000 70.54853  ? 55  GLU A HG2  1 
ATOM   829  H HG3  . GLU A 1 55  ? 0.63033   11.10835  2.45173   1.000 70.54853  ? 55  GLU A HG3  1 
ATOM   830  N N    . ASP A 1 56  ? 5.39546   11.32285  1.08486   1.000 51.28329  ? 56  ASP A N    1 
ATOM   831  C CA   . ASP A 1 56  ? 6.69837   11.97473  0.99653   1.000 53.25897  ? 56  ASP A CA   1 
ATOM   832  C C    . ASP A 1 56  ? 6.91840   12.59535  -0.37842  1.000 53.72176  ? 56  ASP A C    1 
ATOM   833  O O    . ASP A 1 56  ? 7.37753   13.73810  -0.48825  1.000 56.32184  ? 56  ASP A O    1 
ATOM   834  C CB   . ASP A 1 56  ? 7.81097   10.97454  1.30300   1.000 60.74426  ? 56  ASP A CB   1 
ATOM   835  C CG   . ASP A 1 56  ? 9.17287   11.47248  0.85811   1.000 69.85905  ? 56  ASP A CG   1 
ATOM   836  O OD1  . ASP A 1 56  ? 9.72355   12.37860  1.51882   1.000 69.68554  ? 56  ASP A OD1  1 
ATOM   837  O OD2  . ASP A 1 56  ? 9.68605   10.96766  -0.16266  1.000 75.68697  ? 56  ASP A OD2  1 
ATOM   838  H H    . ASP A 1 56  ? 5.42704   10.46703  1.16343   1.000 61.53371  ? 56  ASP A H    1 
ATOM   839  H HA   . ASP A 1 56  ? 6.72920   12.68214  1.65949   1.000 63.90454  ? 56  ASP A HA   1 
ATOM   840  H HB2  . ASP A 1 56  ? 7.84422   10.81973  2.25999   1.000 72.88689  ? 56  ASP A HB2  1 
ATOM   841  H HB3  . ASP A 1 56  ? 7.62734   10.14296  0.83860   1.000 72.88689  ? 56  ASP A HB3  1 
ATOM   842  N N    . LEU A 1 57  ? 6.61927   11.84602  -1.44223  1.000 52.48367  ? 57  LEU A N    1 
ATOM   843  C CA   . LEU A 1 57  ? 6.82251   12.36552  -2.79071  1.000 50.61569  ? 57  LEU A CA   1 
ATOM   844  C C    . LEU A 1 57  ? 6.02134   13.63963  -3.01890  1.000 48.19439  ? 57  LEU A C    1 
ATOM   845  O O    . LEU A 1 57  ? 6.51428   14.59086  -3.63617  1.000 57.73984  ? 57  LEU A O    1 
ATOM   846  C CB   . LEU A 1 57  ? 6.43455   11.30732  -3.82304  1.000 50.80672  ? 57  LEU A CB   1 
ATOM   847  C CG   . LEU A 1 57  ? 7.35764   10.09450  -3.93194  1.000 53.90627  ? 57  LEU A CG   1 
ATOM   848  C CD1  . LEU A 1 57  ? 6.60460   8.92104   -4.52846  1.000 48.45041  ? 57  LEU A CD1  1 
ATOM   849  C CD2  . LEU A 1 57  ? 8.58281   10.42357  -4.76886  1.000 53.95607  ? 57  LEU A CD2  1 
ATOM   850  H H    . LEU A 1 57  ? 6.30267   11.04710  -1.40929  1.000 62.97417  ? 57  LEU A H    1 
ATOM   851  H HA   . LEU A 1 57  ? 7.76311   12.57353  -2.90432  1.000 60.73260  ? 57  LEU A HA   1 
ATOM   852  H HB2  . LEU A 1 57  ? 5.55195   10.97497  -3.59616  1.000 60.96184  ? 57  LEU A HB2  1 
ATOM   853  H HB3  . LEU A 1 57  ? 6.41540   11.73086  -4.69548  1.000 60.96184  ? 57  LEU A HB3  1 
ATOM   854  H HG   . LEU A 1 57  ? 7.66326   9.84591   -3.04554  1.000 64.68129  ? 57  LEU A HG   1 
ATOM   855  H HD11 . LEU A 1 57  ? 7.24325   8.25441   -4.82617  1.000 58.13426  ? 57  LEU A HD11 1 
ATOM   856  H HD12 . LEU A 1 57  ? 6.02247   8.54225   -3.85131  1.000 58.13426  ? 57  LEU A HD12 1 
ATOM   857  H HD13 . LEU A 1 57  ? 6.07766   9.23340   -5.28057  1.000 58.13426  ? 57  LEU A HD13 1 
ATOM   858  H HD21 . LEU A 1 57  ? 8.34389   10.38284  -5.70810  1.000 64.74106  ? 57  LEU A HD21 1 
ATOM   859  H HD22 . LEU A 1 57  ? 8.88859   11.31616  -4.54374  1.000 64.74106  ? 57  LEU A HD22 1 
ATOM   860  H HD23 . LEU A 1 57  ? 9.27969   9.77685   -4.57648  1.000 64.74106  ? 57  LEU A HD23 1 
ATOM   861  N N    . LEU A 1 58  ? 4.78439   13.67915  -2.52165  1.000 52.04191  ? 58  LEU A N    1 
ATOM   862  C CA   . LEU A 1 58  ? 3.90334   14.80395  -2.81492  1.000 58.60258  ? 58  LEU A CA   1 
ATOM   863  C C    . LEU A 1 58  ? 4.36801   16.07356  -2.11253  1.000 56.62778  ? 58  LEU A C    1 
ATOM   864  O O    . LEU A 1 58  ? 4.46761   17.13724  -2.73610  1.000 57.91304  ? 58  LEU A O    1 
ATOM   865  C CB   . LEU A 1 58  ? 2.47068   14.46476  -2.40717  1.000 47.92065  ? 58  LEU A CB   1 
ATOM   866  C CG   . LEU A 1 58  ? 1.44494   15.54621  -2.74293  1.000 51.57988  ? 58  LEU A CG   1 
ATOM   867  C CD1  . LEU A 1 58  ? 1.40988   15.80618  -4.23853  1.000 57.56475  ? 58  LEU A CD1  1 
ATOM   868  C CD2  . LEU A 1 58  ? 0.08622   15.14044  -2.23991  1.000 57.82904  ? 58  LEU A CD2  1 
ATOM   869  H H    . LEU A 1 58  ? 4.43693   13.07448  -2.01843  1.000 62.44406  ? 58  LEU A H    1 
ATOM   870  H HA   . LEU A 1 58  ? 3.92003   14.96675  -3.77101  1.000 70.31686  ? 58  LEU A HA   1 
ATOM   871  H HB2  . LEU A 1 58  ? 2.20317   13.65328  -2.86634  1.000 57.49855  ? 58  LEU A HB2  1 
ATOM   872  H HB3  . LEU A 1 58  ? 2.44778   14.32582  -1.44744  1.000 57.49855  ? 58  LEU A HB3  1 
ATOM   873  H HG   . LEU A 1 58  ? 1.69749   16.37477  -2.30634  1.000 61.88962  ? 58  LEU A HG   1 
ATOM   874  H HD11 . LEU A 1 58  ? 0.60052   16.29493  -4.45522  1.000 69.07148  ? 58  LEU A HD11 1 
ATOM   875  H HD12 . LEU A 1 58  ? 2.18840   16.32897  -4.48653  1.000 69.07148  ? 58  LEU A HD12 1 
ATOM   876  H HD13 . LEU A 1 58  ? 1.41885   14.95685  -4.70700  1.000 69.07148  ? 58  LEU A HD13 1 
ATOM   877  H HD21 . LEU A 1 58  ? -0.57633  15.75831  -2.58654  1.000 69.38862  ? 58  LEU A HD21 1 
ATOM   878  H HD22 . LEU A 1 58  ? -0.10821  14.24083  -2.54619  1.000 69.38862  ? 58  LEU A HD22 1 
ATOM   879  H HD23 . LEU A 1 58  ? 0.08766   15.16666  -1.27027  1.000 69.38862  ? 58  LEU A HD23 1 
ATOM   880  N N    . ILE A 1 59  ? 4.64624   15.98597  -0.80869  1.000 51.44289  ? 59  ILE A N    1 
ATOM   881  C CA   . ILE A 1 59  ? 5.01336   17.17996  -0.05178  1.000 56.92907  ? 59  ILE A CA   1 
ATOM   882  C C    . ILE A 1 59  ? 6.22955   17.85047  -0.67585  1.000 55.10793  ? 59  ILE A C    1 
ATOM   883  O O    . ILE A 1 59  ? 6.38165   19.07622  -0.60178  1.000 53.47110  ? 59  ILE A O    1 
ATOM   884  C CB   . ILE A 1 59  ? 5.24341   16.81522  1.43055   1.000 53.09370  ? 59  ILE A CB   1 
ATOM   885  C CG1  . ILE A 1 59  ? 4.94002   18.01467  2.33465   1.000 50.98022  ? 59  ILE A CG1  1 
ATOM   886  C CG2  . ILE A 1 59  ? 6.66468   16.32126  1.65567   1.000 44.52219  ? 59  ILE A CG2  1 
ATOM   887  C CD1  . ILE A 1 59  ? 4.76650   17.64595  3.80780   1.000 50.47954  ? 59  ILE A CD1  1 
ATOM   888  H H    . ILE A 1 59  ? 4.62954   15.25955  -0.34866  1.000 61.72524  ? 59  ILE A H    1 
ATOM   889  H HA   . ILE A 1 59  ? 4.28128   17.81545  -0.08506  1.000 68.30866  ? 59  ILE A HA   1 
ATOM   890  H HB   . ILE A 1 59  ? 4.63318   16.09644  1.65832   1.000 63.70621  ? 59  ILE A HB   1 
ATOM   891  H HG12 . ILE A 1 59  ? 5.67358   18.64621  2.27180   1.000 61.17003  ? 59  ILE A HG12 1 
ATOM   892  H HG13 . ILE A 1 59  ? 4.11699   18.43124  2.03465   1.000 61.17003  ? 59  ILE A HG13 1 
ATOM   893  H HG21 . ILE A 1 59  ? 6.70645   15.85627  2.50593   1.000 53.42040  ? 59  ILE A HG21 1 
ATOM   894  H HG22 . ILE A 1 59  ? 6.90683   15.71742  0.93619   1.000 53.42040  ? 59  ILE A HG22 1 
ATOM   895  H HG23 . ILE A 1 59  ? 7.26581   17.08248  1.66508   1.000 53.42040  ? 59  ILE A HG23 1 
ATOM   896  H HD11 . ILE A 1 59  ? 5.63927   17.47736  4.19607   1.000 60.56922  ? 59  ILE A HD11 1 
ATOM   897  H HD12 . ILE A 1 59  ? 4.33595   18.38263  4.26913   1.000 60.56922  ? 59  ILE A HD12 1 
ATOM   898  H HD13 . ILE A 1 59  ? 4.21674   16.84932  3.87132   1.000 60.56922  ? 59  ILE A HD13 1 
ATOM   899  N N    . ARG A 1 60  ? 7.09561   17.07262  -1.32755  1.000 47.65095  ? 60  ARG A N    1 
ATOM   900  C CA   . ARG A 1 60  ? 8.24731   17.65538  -2.00317  1.000 53.96275  ? 60  ARG A CA   1 
ATOM   901  C C    . ARG A 1 60  ? 7.85602   18.45185  -3.24320  1.000 58.45159  ? 60  ARG A C    1 
ATOM   902  O O    . ARG A 1 60  ? 8.66635   19.24775  -3.73051  1.000 52.18042  ? 60  ARG A O    1 
ATOM   903  C CB   . ARG A 1 60  ? 9.23741   16.55496  -2.38870  1.000 35.53779  ? 60  ARG A CB   1 
ATOM   904  H H    . ARG A 1 60  ? 7.03739   16.21694  -1.39099  1.000 57.17491  ? 60  ARG A H    1 
ATOM   905  H HA   . ARG A 1 60  ? 8.69022   18.26183  -1.38920  1.000 64.74907  ? 60  ARG A HA   1 
ATOM   906  N N    . LYS A 1 61  ? 6.64085   18.26479  -3.75755  1.000 56.27321  ? 61  LYS A N    1 
ATOM   907  C CA   . LYS A 1 61  ? 6.21866   18.89180  -5.00343  1.000 55.27109  ? 61  LYS A CA   1 
ATOM   908  C C    . LYS A 1 61  ? 5.52724   20.22561  -4.75019  1.000 52.59742  ? 61  LYS A C    1 
ATOM   909  O O    . LYS A 1 61  ? 4.77000   20.37857  -3.78706  1.000 52.77788  ? 61  LYS A O    1 
ATOM   910  C CB   . LYS A 1 61  ? 5.26483   17.97452  -5.77321  1.000 59.27225  ? 61  LYS A CB   1 
ATOM   911  C CG   . LYS A 1 61  ? 5.88248   16.68426  -6.27137  1.000 58.03321  ? 61  LYS A CG   1 
ATOM   912  C CD   . LYS A 1 61  ? 6.77822   16.91962  -7.47422  1.000 54.93836  ? 61  LYS A CD   1 
ATOM   913  C CE   . LYS A 1 61  ? 7.28219   15.60553  -8.04483  1.000 52.95987  ? 61  LYS A CE   1 
ATOM   914  N NZ   . LYS A 1 61  ? 7.78976   14.69130  -6.98276  1.000 78.13084  ? 61  LYS A NZ   1 
ATOM   915  H H    . LYS A 1 61  ? 6.03597   17.77151  -3.39646  1.000 67.52162  ? 61  LYS A H    1 
ATOM   916  H HA   . LYS A 1 61  ? 7.00822   19.05795  -5.54185  1.000 66.31908  ? 61  LYS A HA   1 
ATOM   917  H HB2  . LYS A 1 61  ? 4.52778   17.73774  -5.18874  1.000 71.12047  ? 61  LYS A HB2  1 
ATOM   918  H HB3  . LYS A 1 61  ? 4.93306   18.45619  -6.54704  1.000 71.12047  ? 61  LYS A HB3  1 
ATOM   919  H HG2  . LYS A 1 61  ? 6.41886   16.29177  -5.56487  1.000 69.63363  ? 61  LYS A HG2  1 
ATOM   920  H HG3  . LYS A 1 61  ? 5.17761   16.07112  -6.53237  1.000 69.63363  ? 61  LYS A HG3  1 
ATOM   921  H HD2  . LYS A 1 61  ? 6.27727   17.38167  -8.16448  1.000 65.91980  ? 61  LYS A HD2  1 
ATOM   922  H HD3  . LYS A 1 61  ? 7.54398   17.45191  -7.20744  1.000 65.91980  ? 61  LYS A HD3  1 
ATOM   923  H HE2  . LYS A 1 61  ? 6.55549   15.15884  -8.50664  1.000 63.54562  ? 61  LYS A HE2  1 
ATOM   924  H HE3  . LYS A 1 61  ? 8.00821   15.78383  -8.66290  1.000 63.54562  ? 61  LYS A HE3  1 
ATOM   925  H HZ1  . LYS A 1 61  ? 8.32989   15.13495  -6.43182  1.000 93.75078  ? 61  LYS A HZ1  1 
ATOM   926  H HZ2  . LYS A 1 61  ? 7.10873   14.36025  -6.51510  1.000 93.75078  ? 61  LYS A HZ2  1 
ATOM   927  H HZ3  . LYS A 1 61  ? 8.24163   14.01856  -7.35064  1.000 93.75078  ? 61  LYS A HZ3  1 
ATOM   928  N N    . SER A 1 62  ? 5.77699   21.18126  -5.63811  1.000 51.97339  ? 62  SER A N    1 
ATOM   929  C CA   . SER A 1 62  ? 5.10613   22.47135  -5.63256  1.000 57.48122  ? 62  SER A CA   1 
ATOM   930  C C    . SER A 1 62  ? 4.12808   22.54329  -6.79965  1.000 58.76491  ? 62  SER A C    1 
ATOM   931  O O    . SER A 1 62  ? 4.16551   21.73066  -7.72895  1.000 52.56979  ? 62  SER A O    1 
ATOM   932  C CB   . SER A 1 62  ? 6.12290   23.61751  -5.70701  1.000 53.82744  ? 62  SER A CB   1 
ATOM   933  O OG   . SER A 1 62  ? 6.97171   23.48350  -6.83384  1.000 60.82234  ? 62  SER A OG   1 
ATOM   934  H H    . SER A 1 62  ? 6.35061   21.10086  -6.27380  1.000 62.36184  ? 62  SER A H    1 
ATOM   935  H HA   . SER A 1 62  ? 4.60741   22.57362  -4.80690  1.000 68.97124  ? 62  SER A HA   1 
ATOM   936  H HB2  . SER A 1 62  ? 5.64345   24.45808  -5.77386  1.000 64.58670  ? 62  SER A HB2  1 
ATOM   937  H HB3  . SER A 1 62  ? 6.66541   23.60806  -4.90296  1.000 64.58670  ? 62  SER A HB3  1 
ATOM   938  H HG   . SER A 1 62  ? 6.51204   23.37528  -7.52853  1.000 72.98058  ? 62  SER A HG   1 
ATOM   939  N N    . ASN A 1 63  ? 3.24707   23.54563  -6.74076  1.000 55.31673  ? 63  ASN A N    1 
ATOM   940  C CA   . ASN A 1 63  ? 2.20199   23.67967  -7.75128  1.000 51.60919  ? 63  ASN A CA   1 
ATOM   941  C C    . ASN A 1 63  ? 2.78343   23.80606  -9.15620  1.000 56.08561  ? 63  ASN A C    1 
ATOM   942  O O    . ASN A 1 63  ? 2.19999   23.29785  -10.12096 1.000 45.28998  ? 63  ASN A O    1 
ATOM   943  C CB   . ASN A 1 63  ? 1.31849   24.88770  -7.43366  1.000 51.54546  ? 63  ASN A CB   1 
ATOM   944  C CG   . ASN A 1 63  ? 0.37571   24.63448  -6.27212  1.000 54.95325  ? 63  ASN A CG   1 
ATOM   945  O OD1  . ASN A 1 63  ? -0.00754  23.49603  -6.00559  1.000 54.10200  ? 63  ASN A OD1  1 
ATOM   946  N ND2  . ASN A 1 63  ? -0.00834  25.70004  -5.57788  1.000 49.25406  ? 63  ASN A ND2  1 
ATOM   947  H H    . ASN A 1 63  ? 3.23421   24.15341  -6.13246  1.000 66.37385  ? 63  ASN A H    1 
ATOM   948  H HA   . ASN A 1 63  ? 1.65219   22.88086  -7.72836  1.000 61.92480  ? 63  ASN A HA   1 
ATOM   949  H HB2  . ASN A 1 63  ? 1.88402   25.64111  -7.20248  1.000 61.84832  ? 63  ASN A HB2  1 
ATOM   950  H HB3  . ASN A 1 63  ? 0.78307   25.10180  -8.21365  1.000 61.84832  ? 63  ASN A HB3  1 
ATOM   951  H HD21 . ASN A 1 63  ? -0.54241  25.60854  -4.91005  1.000 59.09864  ? 63  ASN A HD21 1 
ATOM   952  H HD22 . ASN A 1 63  ? 0.27712   26.48132  -5.79629  1.000 59.09864  ? 63  ASN A HD22 1 
ATOM   953  N N    . HIS A 1 64  ? 3.92439   24.48232  -9.29955  1.000 56.36290  ? 64  HIS A N    1 
ATOM   954  C CA   . HIS A 1 64  ? 4.49508   24.70442  -10.62461 1.000 58.32224  ? 64  HIS A CA   1 
ATOM   955  C C    . HIS A 1 64  ? 5.17844   23.46448  -11.19198 1.000 53.26646  ? 64  HIS A C    1 
ATOM   956  O O    . HIS A 1 64  ? 5.63673   23.50166  -12.33916 1.000 53.47517  ? 64  HIS A O    1 
ATOM   957  C CB   . HIS A 1 64  ? 5.47778   25.88520  -10.59136 1.000 57.46783  ? 64  HIS A CB   1 
ATOM   958  C CG   . HIS A 1 64  ? 6.86855   25.51991  -10.17129 1.000 67.19166  ? 64  HIS A CG   1 
ATOM   959  N ND1  . HIS A 1 64  ? 7.22218   25.32014  -8.85420  1.000 70.55724  ? 64  HIS A ND1  1 
ATOM   960  C CD2  . HIS A 1 64  ? 8.00030   25.34453  -10.89441 1.000 67.67841  ? 64  HIS A CD2  1 
ATOM   961  C CE1  . HIS A 1 64  ? 8.50815   25.02473  -8.78509  1.000 70.29126  ? 64  HIS A CE1  1 
ATOM   962  N NE2  . HIS A 1 64  ? 9.00316   25.03040  -10.00956 1.000 71.42029  ? 64  HIS A NE2  1 
ATOM   963  H H    . HIS A 1 64  ? 4.37971   24.81755  -8.65155  1.000 67.62925  ? 64  HIS A H    1 
ATOM   964  H HA   . HIS A 1 64  ? 3.77876   24.94483  -11.23287 1.000 69.98046  ? 64  HIS A HA   1 
ATOM   965  H HB2  . HIS A 1 64  ? 5.53102   26.26875  -11.48071 1.000 68.95517  ? 64  HIS A HB2  1 
ATOM   966  H HB3  . HIS A 1 64  ? 5.14592   26.54655  -9.96416  1.000 68.95517  ? 64  HIS A HB3  1 
ATOM   967  H HD2  . HIS A 1 64  ? 8.08304   25.42224  -11.81746 1.000 81.20787  ? 64  HIS A HD2  1 
ATOM   968  H HE1  . HIS A 1 64  ? 8.98380   24.84364  -8.00671  1.000 84.34329  ? 64  HIS A HE1  1 
ATOM   969  H HE2  . HIS A 1 64  ? 9.82059   24.86439  -10.21897 1.000 85.69812  ? 64  HIS A HE2  1 
ATOM   970  N N    . ASN A 1 65  ? 5.25101   22.37073  -10.42950 1.000 54.34029  ? 65  ASN A N    1 
ATOM   971  C CA   . ASN A 1 65  ? 5.74334   21.10877  -10.96615 1.000 53.70199  ? 65  ASN A CA   1 
ATOM   972  C C    . ASN A 1 65  ? 4.69050   20.36687  -11.78079 1.000 60.02490  ? 65  ASN A C    1 
ATOM   973  O O    . ASN A 1 65  ? 5.04020   19.44420  -12.52535 1.000 59.06182  ? 65  ASN A O    1 
ATOM   974  C CB   . ASN A 1 65  ? 6.21911   20.19192  -9.83508  1.000 57.08914  ? 65  ASN A CB   1 
ATOM   975  C CG   . ASN A 1 65  ? 7.47166   20.70217  -9.14839  1.000 58.23944  ? 65  ASN A CG   1 
ATOM   976  O OD1  . ASN A 1 65  ? 7.54479   20.73707  -7.92107  1.000 57.23094  ? 65  ASN A OD1  1 
ATOM   977  N ND2  . ASN A 1 65  ? 8.46637   21.09512  -9.93672  1.000 64.31234  ? 65  ASN A ND2  1 
ATOM   978  H H    . ASN A 1 65  ? 5.02116   22.33699  -9.60147  1.000 65.20212  ? 65  ASN A H    1 
ATOM   979  H HA   . ASN A 1 65  ? 6.50077   21.30343  -11.54000 1.000 64.43616  ? 65  ASN A HA   1 
ATOM   980  H HB2  . ASN A 1 65  ? 5.51837   20.12446  -9.16777  1.000 68.50074  ? 65  ASN A HB2  1 
ATOM   981  H HB3  . ASN A 1 65  ? 6.41446   19.31502  -10.20083 1.000 68.50074  ? 65  ASN A HB3  1 
ATOM   982  H HD21 . ASN A 1 65  ? 9.19637   21.39198  -9.59236  1.000 77.16858  ? 65  ASN A HD21 1 
ATOM   983  H HD22 . ASN A 1 65  ? 8.38023   21.05260  -10.79134 1.000 77.16858  ? 65  ASN A HD22 1 
ATOM   984  N N    . PHE A 1 66  ? 3.41847   20.73781  -11.64972 1.000 50.06015  ? 66  PHE A N    1 
ATOM   985  C CA   . PHE A 1 66  ? 2.32338   20.05653  -12.32828 1.000 52.36918  ? 66  PHE A CA   1 
ATOM   986  C C    . PHE A 1 66  ? 1.89529   20.86818  -13.54409 1.000 54.37642  ? 66  PHE A C    1 
ATOM   987  O O    . PHE A 1 66  ? 1.42974   22.00443  -13.40297 1.000 52.38300  ? 66  PHE A O    1 
ATOM   988  C CB   . PHE A 1 66  ? 1.13680   19.85544  -11.38527 1.000 41.49917  ? 66  PHE A CB   1 
ATOM   989  C CG   . PHE A 1 66  ? 1.41533   18.91194  -10.25153 1.000 46.36580  ? 66  PHE A CG   1 
ATOM   990  C CD1  . PHE A 1 66  ? 1.52408   17.55077  -10.47761 1.000 46.93522  ? 66  PHE A CD1  1 
ATOM   991  C CD2  . PHE A 1 66  ? 1.55922   19.38363  -8.95826  1.000 51.10726  ? 66  PHE A CD2  1 
ATOM   992  C CE1  . PHE A 1 66  ? 1.77819   16.67996  -9.43749  1.000 50.78512  ? 66  PHE A CE1  1 
ATOM   993  C CE2  . PHE A 1 66  ? 1.81260   18.51549  -7.91398  1.000 48.68727  ? 66  PHE A CE2  1 
ATOM   994  C CZ   . PHE A 1 66  ? 1.92244   17.16293  -8.15486  1.000 47.78483  ? 66  PHE A CZ   1 
ATOM   995  H H    . PHE A 1 66  ? 3.16093   21.39706  -11.16118 1.000 60.06596  ? 66  PHE A H    1 
ATOM   996  H HA   . PHE A 1 66  ? 2.63219   19.18819  -12.63082 1.000 62.83679  ? 66  PHE A HA   1 
ATOM   997  H HB2  . PHE A 1 66  ? 0.89380   20.71323  -11.00310 1.000 49.79277  ? 66  PHE A HB2  1 
ATOM   998  H HB3  . PHE A 1 66  ? 0.39276   19.49579  -11.89316 1.000 49.79277  ? 66  PHE A HB3  1 
ATOM   999  H HD1  . PHE A 1 66  ? 1.42472   17.21901  -11.34073 1.000 56.31603  ? 66  PHE A HD1  1 
ATOM   1000 H HD2  . PHE A 1 66  ? 1.48448   20.29530  -8.79042  1.000 61.32249  ? 66  PHE A HD2  1 
ATOM   1001 H HE1  . PHE A 1 66  ? 1.85205   15.76762  -9.60209  1.000 60.93592  ? 66  PHE A HE1  1 
ATOM   1002 H HE2  . PHE A 1 66  ? 1.90898   18.84349  -7.04909  1.000 58.41849  ? 66  PHE A HE2  1 
ATOM   1003 H HZ   . PHE A 1 66  ? 2.09361   16.57719  -7.45306  1.000 57.33556  ? 66  PHE A HZ   1 
ATOM   1004 N N    . LEU A 1 67  ? 2.04566   20.28169  -14.73010 1.000 48.04391  ? 67  LEU A N    1 
ATOM   1005 C CA   . LEU A 1 67  ? 1.62686   20.90465  -15.97873 1.000 49.07493  ? 67  LEU A CA   1 
ATOM   1006 C C    . LEU A 1 67  ? 0.28623   20.31909  -16.40697 1.000 44.14100  ? 67  LEU A C    1 
ATOM   1007 O O    . LEU A 1 67  ? 0.19747   19.12647  -16.71729 1.000 44.31710  ? 67  LEU A O    1 
ATOM   1008 C CB   . LEU A 1 67  ? 2.66604   20.68652  -17.07739 1.000 51.24584  ? 67  LEU A CB   1 
ATOM   1009 C CG   . LEU A 1 67  ? 4.07364   21.23398  -16.84701 1.000 60.10769  ? 67  LEU A CG   1 
ATOM   1010 C CD1  . LEU A 1 67  ? 4.91731   20.31709  -15.97504 1.000 62.13656  ? 67  LEU A CD1  1 
ATOM   1011 C CD2  . LEU A 1 67  ? 4.74015   21.46082  -18.18530 1.000 57.17078  ? 67  LEU A CD2  1 
ATOM   1012 H H    . LEU A 1 67  ? 2.39651   19.50384  -14.83714 1.000 57.64647  ? 67  LEU A H    1 
ATOM   1013 H HA   . LEU A 1 67  ? 1.52129   21.85817  -15.83532 1.000 58.88369  ? 67  LEU A HA   1 
ATOM   1014 H HB2  . LEU A 1 67  ? 2.75696   19.73021  -17.21196 1.000 61.48877  ? 67  LEU A HB2  1 
ATOM   1015 H HB3  . LEU A 1 67  ? 2.33257   21.10516  -17.88636 1.000 61.48877  ? 67  LEU A HB3  1 
ATOM   1016 H HG   . LEU A 1 67  ? 4.00677   22.07492  -16.36821 1.000 72.12300  ? 67  LEU A HG   1 
ATOM   1017 H HD11 . LEU A 1 67  ? 4.51632   20.26270  -15.09348 1.000 74.55765  ? 67  LEU A HD11 1 
ATOM   1018 H HD12 . LEU A 1 67  ? 4.94732   19.43605  -16.37971 1.000 74.55765  ? 67  LEU A HD12 1 
ATOM   1019 H HD13 . LEU A 1 67  ? 5.81388   20.68134  -15.90871 1.000 74.55765  ? 67  LEU A HD13 1 
ATOM   1020 H HD21 . LEU A 1 67  ? 4.36720   22.25820  -18.59272 1.000 68.59871  ? 67  LEU A HD21 1 
ATOM   1021 H HD22 . LEU A 1 67  ? 5.69362   21.57454  -18.04800 1.000 68.59871  ? 67  LEU A HD22 1 
ATOM   1022 H HD23 . LEU A 1 67  ? 4.57720   20.69183  -18.75363 1.000 68.59871  ? 67  LEU A HD23 1 
ATOM   1023 N N    . VAL A 1 68  ? -0.74798  21.15451  -16.43016 1.000 43.34253  ? 68  VAL A N    1 
ATOM   1024 C CA   . VAL A 1 68  ? -2.06656  20.76744  -16.91964 1.000 46.38308  ? 68  VAL A CA   1 
ATOM   1025 C C    . VAL A 1 68  ? -2.31587  21.51315  -18.22243 1.000 46.26880  ? 68  VAL A C    1 
ATOM   1026 O O    . VAL A 1 68  ? -2.27435  22.74958  -18.25829 1.000 47.25432  ? 68  VAL A O    1 
ATOM   1027 C CB   . VAL A 1 68  ? -3.17089  21.06313  -15.89393 1.000 42.51361  ? 68  VAL A CB   1 
ATOM   1028 C CG1  . VAL A 1 68  ? -4.53100  20.64024  -16.43847 1.000 41.35302  ? 68  VAL A CG1  1 
ATOM   1029 C CG2  . VAL A 1 68  ? -2.88007  20.34633  -14.58687 1.000 42.53208  ? 68  VAL A CG2  1 
ATOM   1030 H H    . VAL A 1 68  ? -0.70859  21.97030  -16.16083 1.000 52.00481  ? 68  VAL A H    1 
ATOM   1031 H HA   . VAL A 1 68  ? -2.07201  19.81467  -17.10158 1.000 55.65347  ? 68  VAL A HA   1 
ATOM   1032 H HB   . VAL A 1 68  ? -3.19462  22.01765  -15.72299 1.000 51.01010  ? 68  VAL A HB   1 
ATOM   1033 H HG11 . VAL A 1 68  ? -5.20755  20.80923  -15.76422 1.000 49.61739  ? 68  VAL A HG11 1 
ATOM   1034 H HG12 . VAL A 1 68  ? -4.72491  21.15442  -17.23779 1.000 49.61739  ? 68  VAL A HG12 1 
ATOM   1035 H HG13 . VAL A 1 68  ? -4.50556  19.69431  -16.65173 1.000 49.61739  ? 68  VAL A HG13 1 
ATOM   1036 H HG21 . VAL A 1 68  ? -3.68794  20.32782  -14.05031 1.000 51.03227  ? 68  VAL A HG21 1 
ATOM   1037 H HG22 . VAL A 1 68  ? -2.59094  19.44095  -14.78076 1.000 51.03227  ? 68  VAL A HG22 1 
ATOM   1038 H HG23 . VAL A 1 68  ? -2.17993  20.82310  -14.11423 1.000 51.03227  ? 68  VAL A HG23 1 
ATOM   1039 N N    . GLN A 1 69  ? -2.58002  20.76161  -19.28842 1.000 45.91285  ? 69  GLN A N    1 
ATOM   1040 C CA   . GLN A 1 69  ? -2.82216  21.32212  -20.60996 1.000 49.94718  ? 69  GLN A CA   1 
ATOM   1041 C C    . GLN A 1 69  ? -4.13649  20.77386  -21.14184 1.000 43.99641  ? 69  GLN A C    1 
ATOM   1042 O O    . GLN A 1 69  ? -4.33129  19.55495  -21.18793 1.000 43.67443  ? 69  GLN A O    1 
ATOM   1043 C CB   . GLN A 1 69  ? -1.67586  20.98808  -21.56983 1.000 51.30521  ? 69  GLN A CB   1 
ATOM   1044 C CG   . GLN A 1 69  ? -1.66253  21.83081  -22.83320 1.000 64.33237  ? 69  GLN A CG   1 
ATOM   1045 C CD   . GLN A 1 69  ? -0.53601  21.44985  -23.77438 1.000 74.74869  ? 69  GLN A CD   1 
ATOM   1046 O OE1  . GLN A 1 69  ? 0.46175   20.85656  -23.36084 1.000 62.54193  ? 69  GLN A OE1  1 
ATOM   1047 N NE2  . GLN A 1 69  ? -0.69207  21.78627  -25.04982 1.000 78.35502  ? 69  GLN A NE2  1 
ATOM   1048 H H    . GLN A 1 69  ? -2.62490  19.90302  -19.26810 1.000 55.08920  ? 69  GLN A H    1 
ATOM   1049 H HA   . GLN A 1 69  ? -2.89473  22.28754  -20.55001 1.000 59.93039  ? 69  GLN A HA   1 
ATOM   1050 H HB2  . GLN A 1 69  ? -0.83378  21.13184  -21.11032 1.000 61.56003  ? 69  GLN A HB2  1 
ATOM   1051 H HB3  . GLN A 1 69  ? -1.75413  20.05859  -21.83593 1.000 61.56003  ? 69  GLN A HB3  1 
ATOM   1052 H HG2  . GLN A 1 69  ? -2.50190  21.70944  -23.30397 1.000 77.19262  ? 69  GLN A HG2  1 
ATOM   1053 H HG3  . GLN A 1 69  ? -1.54983  22.76329  -22.59097 1.000 77.19262  ? 69  GLN A HG3  1 
ATOM   1054 H HE21 . GLN A 1 69  ? -1.40385  22.19783  -25.30197 1.000 94.01980  ? 69  GLN A HE21 1 
ATOM   1055 H HE22 . GLN A 1 69  ? -0.08134  21.59252  -25.62346 1.000 94.01980  ? 69  GLN A HE22 1 
ATOM   1056 N N    . ALA A 1 70  ? -5.03134  21.67451  -21.53939 1.000 55.21401  ? 70  ALA A N    1 
ATOM   1057 C CA   . ALA A 1 70  ? -6.35511  21.32408  -22.04656 1.000 45.67595  ? 70  ALA A CA   1 
ATOM   1058 C C    . ALA A 1 70  ? -6.38991  21.66475  -23.53390 1.000 52.10502  ? 70  ALA A C    1 
ATOM   1059 O O    . ALA A 1 70  ? -6.94172  22.68428  -23.95034 1.000 57.70324  ? 70  ALA A O    1 
ATOM   1060 C CB   . ALA A 1 70  ? -7.44040  22.06392  -21.27125 1.000 49.96893  ? 70  ALA A CB   1 
ATOM   1061 H H    . ALA A 1 70  ? -4.88959  22.52261  -21.52406 1.000 66.25058  ? 70  ALA A H    1 
ATOM   1062 H HA   . ALA A 1 70  ? -6.49857  20.37047  -21.94195 1.000 54.80491  ? 70  ALA A HA   1 
ATOM   1063 H HB1  . ALA A 1 70  ? -7.34687  23.01657  -21.42812 1.000 59.95649  ? 70  ALA A HB1  1 
ATOM   1064 H HB2  . ALA A 1 70  ? -8.30951  21.76188  -21.57836 1.000 59.95649  ? 70  ALA A HB2  1 
ATOM   1065 H HB3  . ALA A 1 70  ? -7.33896  21.87287  -20.32567 1.000 59.95649  ? 70  ALA A HB3  1 
ATOM   1066 N N    . GLY A 1 71  ? -5.79393  20.79176  -24.34011 1.000 59.45127  ? 71  GLY A N    1 
ATOM   1067 C CA   . GLY A 1 71  ? -5.66335  21.05265  -25.75885 1.000 64.89208  ? 71  GLY A CA   1 
ATOM   1068 C C    . GLY A 1 71  ? -4.61987  22.11581  -26.02433 1.000 68.73033  ? 71  GLY A C    1 
ATOM   1069 O O    . GLY A 1 71  ? -3.45927  21.96206  -25.63304 1.000 74.50856  ? 71  GLY A O    1 
ATOM   1070 H H    . GLY A 1 71  ? -5.45835  20.04212  -24.08510 1.000 71.33530  ? 71  GLY A H    1 
ATOM   1071 H HA2  . GLY A 1 71  ? -5.40183  20.23865  -26.21701 1.000 77.86426  ? 71  GLY A HA2  1 
ATOM   1072 H HA3  . GLY A 1 71  ? -6.51366  21.35565  -26.11393 1.000 77.86426  ? 71  GLY A HA3  1 
ATOM   1073 N N    . ASN A 1 72  ? -5.01780  23.20518  -26.68389 1.000 67.18053  ? 72  ASN A N    1 
ATOM   1074 C CA   . ASN A 1 72  ? -4.08830  24.31004  -26.89170 1.000 83.78091  ? 72  ASN A CA   1 
ATOM   1075 C C    . ASN A 1 72  ? -3.87281  25.10487  -25.60879 1.000 79.87311  ? 72  ASN A C    1 
ATOM   1076 O O    . ASN A 1 72  ? -2.78348  25.64875  -25.39209 1.000 79.60473  ? 72  ASN A O    1 
ATOM   1077 C CB   . ASN A 1 72  ? -4.60131  25.22503  -28.00526 1.000 74.67448  ? 72  ASN A CB   1 
ATOM   1078 H H    . ASN A 1 72  ? -5.80314  23.32536  -27.01312 1.000 80.61041  ? 72  ASN A H    1 
ATOM   1079 H HA   . ASN A 1 72  ? -3.23144  23.95166  -27.17142 1.000 100.53086 ? 72  ASN A HA   1 
ATOM   1080 N N    . VAL A 1 73  ? -4.89017  25.16888  -24.74546 1.000 73.07860  ? 73  VAL A N    1 
ATOM   1081 C CA   . VAL A 1 73  ? -4.80419  25.97025  -23.52736 1.000 57.98597  ? 73  VAL A CA   1 
ATOM   1082 C C    . VAL A 1 73  ? -3.85530  25.31996  -22.52315 1.000 68.62543  ? 73  VAL A C    1 
ATOM   1083 O O    . VAL A 1 73  ? -3.60815  24.10818  -22.53889 1.000 70.99544  ? 73  VAL A O    1 
ATOM   1084 C CB   . VAL A 1 73  ? -6.20726  26.15552  -22.92478 1.000 59.53181  ? 73  VAL A CB   1 
ATOM   1085 C CG1  . VAL A 1 73  ? -6.13290  26.79705  -21.55091 1.000 61.13389  ? 73  VAL A CG1  1 
ATOM   1086 C CG2  . VAL A 1 73  ? -7.06754  26.99438  -23.84190 1.000 62.55091  ? 73  VAL A CG2  1 
ATOM   1087 H H    . VAL A 1 73  ? -5.63937  24.75798  -24.84269 1.000 87.68809  ? 73  VAL A H    1 
ATOM   1088 H HA   . VAL A 1 73  ? -4.43764  26.84153  -23.74510 1.000 69.57694  ? 73  VAL A HA   1 
ATOM   1089 H HB   . VAL A 1 73  ? -6.61422  25.28052  -22.82652 1.000 71.43195  ? 73  VAL A HB   1 
ATOM   1090 H HG11 . VAL A 1 73  ? -5.44980  27.48565  -21.56048 1.000 73.35444  ? 73  VAL A HG11 1 
ATOM   1091 H HG12 . VAL A 1 73  ? -6.99445  27.18873  -21.33822 1.000 73.35444  ? 73  VAL A HG12 1 
ATOM   1092 H HG13 . VAL A 1 73  ? -5.90807  26.11714  -20.89664 1.000 73.35444  ? 73  VAL A HG13 1 
ATOM   1093 H HG21 . VAL A 1 73  ? -8.00125  26.80376  -23.66092 1.000 75.05487  ? 73  VAL A HG21 1 
ATOM   1094 H HG22 . VAL A 1 73  ? -6.88346  27.93239  -23.67711 1.000 75.05487  ? 73  VAL A HG22 1 
ATOM   1095 H HG23 . VAL A 1 73  ? -6.85710  26.77276  -24.76250 1.000 75.05487  ? 73  VAL A HG23 1 
ATOM   1096 N N    . GLN A 1 74  ? -3.31197  26.15089  -21.63401 1.000 57.16190  ? 74  GLN A N    1 
ATOM   1097 C CA   . GLN A 1 74  ? -2.49984  25.70024  -20.50958 1.000 62.12782  ? 74  GLN A CA   1 
ATOM   1098 C C    . GLN A 1 74  ? -3.14588  26.21402  -19.22998 1.000 49.63554  ? 74  GLN A C    1 
ATOM   1099 O O    . GLN A 1 74  ? -3.35046  27.42295  -19.08007 1.000 53.05235  ? 74  GLN A O    1 
ATOM   1100 C CB   . GLN A 1 74  ? -1.05966  26.20503  -20.62854 1.000 59.73500  ? 74  GLN A CB   1 
ATOM   1101 C CG   . GLN A 1 74  ? -0.43819  26.03478  -22.01633 1.000 80.61184  ? 74  GLN A CG   1 
ATOM   1102 C CD   . GLN A 1 74  ? 0.60982   24.93757  -22.07003 1.000 84.79971  ? 74  GLN A CD   1 
ATOM   1103 O OE1  . GLN A 1 74  ? 1.37492   24.74447  -21.12367 1.000 84.23242  ? 74  GLN A OE1  1 
ATOM   1104 N NE2  . GLN A 1 74  ? 0.65002   24.21259  -23.18394 1.000 81.04134  ? 74  GLN A NE2  1 
ATOM   1105 H H    . GLN A 1 74  ? -3.40391  27.00543  -21.66418 1.000 68.58806  ? 74  GLN A H    1 
ATOM   1106 H HA   . GLN A 1 74  ? -2.47596  24.73084  -20.48517 1.000 74.54716  ? 74  GLN A HA   1 
ATOM   1107 H HB2  . GLN A 1 74  ? -1.04576  27.15130  -20.41575 1.000 71.67578  ? 74  GLN A HB2  1 
ATOM   1108 H HB3  . GLN A 1 74  ? -0.50797  25.71523  -19.99875 1.000 71.67578  ? 74  GLN A HB3  1 
ATOM   1109 H HG2  . GLN A 1 74  ? -1.13815  25.81001  -22.64912 1.000 96.72798  ? 74  GLN A HG2  1 
ATOM   1110 H HG3  . GLN A 1 74  ? -0.01223  26.86710  -22.27460 1.000 96.72798  ? 74  GLN A HG3  1 
ATOM   1111 H HE21 . GLN A 1 74  ? 0.10027   24.37749  -23.82439 1.000 97.24337  ? 74  GLN A HE21 1 
ATOM   1112 H HE22 . GLN A 1 74  ? 1.22577   23.57879  -23.26395 1.000 97.24337  ? 74  GLN A HE22 1 
ATOM   1113 N N    . LEU A 1 75  ? -3.48068  25.30308  -18.31959 1.000 51.47096  ? 75  LEU A N    1 
ATOM   1114 C CA   . LEU A 1 75  ? -4.11564  25.67763  -17.06397 1.000 48.74243  ? 75  LEU A CA   1 
ATOM   1115 C C    . LEU A 1 75  ? -3.05360  25.92584  -16.00242 1.000 56.47373  ? 75  LEU A C    1 
ATOM   1116 O O    . LEU A 1 75  ? -2.09886  25.15420  -15.87192 1.000 65.07640  ? 75  LEU A O    1 
ATOM   1117 C CB   . LEU A 1 75  ? -5.07510  24.59051  -16.57606 1.000 47.74210  ? 75  LEU A CB   1 
ATOM   1118 C CG   . LEU A 1 75  ? -6.08445  23.95377  -17.53620 1.000 51.11740  ? 75  LEU A CG   1 
ATOM   1119 C CD1  . LEU A 1 75  ? -7.13478  23.19172  -16.72342 1.000 54.48808  ? 75  LEU A CD1  1 
ATOM   1120 C CD2  . LEU A 1 75  ? -6.75414  24.96169  -18.44916 1.000 58.71871  ? 75  LEU A CD2  1 
ATOM   1121 H H    . LEU A 1 75  ? -3.34887  24.45789  -18.40830 1.000 61.75892  ? 75  LEU A H    1 
ATOM   1122 H HA   . LEU A 1 75  ? -4.62870  26.48931  -17.20129 1.000 58.48469  ? 75  LEU A HA   1 
ATOM   1123 H HB2  . LEU A 1 75  ? -4.53102  23.86182  -16.23858 1.000 57.28429  ? 75  LEU A HB2  1 
ATOM   1124 H HB3  . LEU A 1 75  ? -5.59800  24.97546  -15.85544 1.000 57.28429  ? 75  LEU A HB3  1 
ATOM   1125 H HG   . LEU A 1 75  ? -5.60500  23.34450  -18.11913 1.000 61.33465  ? 75  LEU A HG   1 
ATOM   1126 H HD11 . LEU A 1 75  ? -7.55241  23.80216  -16.09585 1.000 65.37947  ? 75  LEU A HD11 1 
ATOM   1127 H HD12 . LEU A 1 75  ? -7.80201  22.83158  -17.32840 1.000 65.37947  ? 75  LEU A HD12 1 
ATOM   1128 H HD13 . LEU A 1 75  ? -6.69979  22.46992  -16.24312 1.000 65.37947  ? 75  LEU A HD13 1 
ATOM   1129 H HD21 . LEU A 1 75  ? -7.15010  24.49303  -19.20048 1.000 70.45623  ? 75  LEU A HD21 1 
ATOM   1130 H HD22 . LEU A 1 75  ? -7.44251  25.43007  -17.95149 1.000 70.45623  ? 75  LEU A HD22 1 
ATOM   1131 H HD23 . LEU A 1 75  ? -6.08836  25.59192  -18.76611 1.000 70.45623  ? 75  LEU A HD23 1 
ATOM   1132 N N    . ARG A 1 76  ? -3.23144  26.99890  -15.23657 1.000 56.14121  ? 76  ARG A N    1 
ATOM   1133 C CA   . ARG A 1 76  ? -2.29053  27.35683  -14.18319 1.000 65.61049  ? 76  ARG A CA   1 
ATOM   1134 C C    . ARG A 1 76  ? -2.74887  26.72445  -12.87359 1.000 55.41998  ? 76  ARG A C    1 
ATOM   1135 O O    . ARG A 1 76  ? -3.86488  26.98211  -12.40821 1.000 53.84022  ? 76  ARG A O    1 
ATOM   1136 C CB   . ARG A 1 76  ? -2.17243  28.87403  -14.04066 1.000 70.60276  ? 76  ARG A CB   1 
ATOM   1137 C CG   . ARG A 1 76  ? -0.85442  29.31939  -13.41057 1.000 73.47754  ? 76  ARG A CG   1 
ATOM   1138 C CD   . ARG A 1 76  ? -0.82021  30.81698  -13.14509 1.000 82.30125  ? 76  ARG A CD   1 
ATOM   1139 N NE   . ARG A 1 76  ? -0.75775  31.60009  -14.37422 1.000 80.58927  ? 76  ARG A NE   1 
ATOM   1140 C CZ   . ARG A 1 76  ? 0.36542   31.97448  -14.97411 1.000 74.84723  ? 76  ARG A CZ   1 
ATOM   1141 N NH1  . ARG A 1 76  ? 1.55279   31.63801  -14.49548 1.000 71.88598  ? 76  ARG A NH1  1 
ATOM   1142 N NH2  . ARG A 1 76  ? 0.29556   32.70650  -16.08235 1.000 72.42848  ? 76  ARG A NH2  1 
ATOM   1143 H H    . ARG A 1 76  ? -3.89623  27.53958  -15.30953 1.000 67.36323  ? 76  ARG A H    1 
ATOM   1144 H HA   . ARG A 1 76  ? -1.41199  27.01134  -14.40615 1.000 78.72635  ? 76  ARG A HA   1 
ATOM   1145 H HB2  . ARG A 1 76  ? -2.23382  29.27758  -14.92059 1.000 84.71708  ? 76  ARG A HB2  1 
ATOM   1146 H HB3  . ARG A 1 76  ? -2.89508  29.19353  -13.47799 1.000 84.71708  ? 76  ARG A HB3  1 
ATOM   1147 H HG2  . ARG A 1 76  ? -0.73464  28.86017  -12.56459 1.000 88.16682  ? 76  ARG A HG2  1 
ATOM   1148 H HG3  . ARG A 1 76  ? -0.12474  29.10279  -14.01185 1.000 88.16682  ? 76  ARG A HG3  1 
ATOM   1149 H HD2  . ARG A 1 76  ? -1.62384  31.07275  -12.66585 1.000 98.75528  ? 76  ARG A HD2  1 
ATOM   1150 H HD3  . ARG A 1 76  ? -0.03617  31.02731  -12.61411 1.000 98.75528  ? 76  ARG A HD3  1 
ATOM   1151 H HE   . ARG A 1 76  ? -1.50153  31.83594  -14.73583 1.000 96.70090  ? 76  ARG A HE   1 
ATOM   1152 H HH11 . ARG A 1 76  ? 1.60951   31.16558  -13.77910 1.000 86.25695  ? 76  ARG A HH11 1 
ATOM   1153 H HH12 . ARG A 1 76  ? 2.26751   31.89182  -14.90089 1.000 86.25695  ? 76  ARG A HH12 1 
ATOM   1154 H HH21 . ARG A 1 76  ? -0.47068  32.93138  -16.40156 1.000 86.90794  ? 76  ARG A HH21 1 
ATOM   1155 H HH22 . ARG A 1 76  ? 1.01664   32.95494  -16.47975 1.000 86.90794  ? 76  ARG A HH22 1 
ATOM   1156 N N    . VAL A 1 77  ? -1.88731  25.90148  -12.28689 1.000 57.94490  ? 77  VAL A N    1 
ATOM   1157 C CA   . VAL A 1 77  ? -2.20100  25.20351  -11.04584 1.000 52.39208  ? 77  VAL A CA   1 
ATOM   1158 C C    . VAL A 1 77  ? -2.01744  26.16087  -9.87247  1.000 56.44142  ? 77  VAL A C    1 
ATOM   1159 O O    . VAL A 1 77  ? -1.01882  26.88610  -9.79654  1.000 60.98870  ? 77  VAL A O    1 
ATOM   1160 C CB   . VAL A 1 77  ? -1.31574  23.95691  -10.89500 1.000 54.17163  ? 77  VAL A CB   1 
ATOM   1161 C CG1  . VAL A 1 77  ? -1.76928  23.10936  -9.71731  1.000 57.81916  ? 77  VAL A CG1  1 
ATOM   1162 C CG2  . VAL A 1 77  ? -1.32496  23.14382  -12.18489 1.000 57.93528  ? 77  VAL A CG2  1 
ATOM   1163 H H    . VAL A 1 77  ? -1.10233  25.72757  -12.59213 1.000 69.52765  ? 77  VAL A H    1 
ATOM   1164 H HA   . VAL A 1 77  ? -3.12901  24.92162  -11.06069 1.000 62.86426  ? 77  VAL A HA   1 
ATOM   1165 H HB   . VAL A 1 77  ? -0.40438  24.23906  -10.71974 1.000 64.99973  ? 77  VAL A HB   1 
ATOM   1166 H HG11 . VAL A 1 77  ? -1.19880  22.32752  -9.65262  1.000 69.37676  ? 77  VAL A HG11 1 
ATOM   1167 H HG12 . VAL A 1 77  ? -1.70255  23.63562  -8.90522  1.000 69.37676  ? 77  VAL A HG12 1 
ATOM   1168 H HG13 . VAL A 1 77  ? -2.68916  22.83672  -9.86013  1.000 69.37676  ? 77  VAL A HG13 1 
ATOM   1169 H HG21 . VAL A 1 77  ? -0.90274  22.28613  -12.02058 1.000 69.51611  ? 77  VAL A HG21 1 
ATOM   1170 H HG22 . VAL A 1 77  ? -2.24317  23.01160  -12.46829 1.000 69.51611  ? 77  VAL A HG22 1 
ATOM   1171 H HG23 . VAL A 1 77  ? -0.83471  23.62853  -12.86725 1.000 69.51611  ? 77  VAL A HG23 1 
ATOM   1172 N N    . ILE A 1 78  ? -2.98114  26.16082  -8.95198  1.000 62.42235  ? 78  ILE A N    1 
ATOM   1173 C CA   . ILE A 1 78  ? -2.92836  27.03163  -7.78191  1.000 57.67690  ? 78  ILE A CA   1 
ATOM   1174 C C    . ILE A 1 78  ? -3.27121  26.23445  -6.53033  1.000 52.37410  ? 78  ILE A C    1 
ATOM   1175 O O    . ILE A 1 78  ? -3.85058  26.76673  -5.57682  1.000 55.27267  ? 78  ILE A O    1 
ATOM   1176 C CB   . ILE A 1 78  ? -3.87803  28.23182  -7.94480  1.000 54.68261  ? 78  ILE A CB   1 
ATOM   1177 C CG1  . ILE A 1 78  ? -5.33855  27.77110  -7.91792  1.000 48.23197  ? 78  ILE A CG1  1 
ATOM   1178 C CG2  . ILE A 1 78  ? -3.57801  28.95863  -9.24593  1.000 52.31894  ? 78  ILE A CG2  1 
ATOM   1179 C CD1  . ILE A 1 78  ? -6.33094  28.89050  -8.10815  1.000 46.19087  ? 78  ILE A CD1  1 
ATOM   1180 H H    . ILE A 1 78  ? -3.68047  25.66131  -8.98403  1.000 74.90060  ? 78  ILE A H    1 
ATOM   1181 H HA   . ILE A 1 78  ? -2.02271  27.36496  -7.68402  1.000 69.20605  ? 78  ILE A HA   1 
ATOM   1182 H HB   . ILE A 1 78  ? -3.73588  28.83925  -7.20201  1.000 65.61291  ? 78  ILE A HB   1 
ATOM   1183 H HG12 . ILE A 1 78  ? -5.47630  27.12859  -8.63144  1.000 57.87214  ? 78  ILE A HG12 1 
ATOM   1184 H HG13 . ILE A 1 78  ? -5.51955  27.35740  -7.05944  1.000 57.87214  ? 78  ILE A HG13 1 
ATOM   1185 H HG21 . ILE A 1 78  ? -4.02049  29.82176  -9.23481  1.000 62.77650  ? 78  ILE A HG21 1 
ATOM   1186 H HG22 . ILE A 1 78  ? -2.61894  29.07959  -9.32620  1.000 62.77650  ? 78  ILE A HG22 1 
ATOM   1187 H HG23 . ILE A 1 78  ? -3.90764  28.42747  -9.98763  1.000 62.77650  ? 78  ILE A HG23 1 
ATOM   1188 H HD11 . ILE A 1 78  ? -6.09304  29.62634  -7.52263  1.000 55.42281  ? 78  ILE A HD11 1 
ATOM   1189 H HD12 . ILE A 1 78  ? -6.30484  29.18191  -9.03297  1.000 55.42281  ? 78  ILE A HD12 1 
ATOM   1190 H HD13 . ILE A 1 78  ? -7.21842  28.56650  -7.88836  1.000 55.42281  ? 78  ILE A HD13 1 
ATOM   1191 N N    . GLY A 1 79  ? -2.90989  24.95856  -6.51964  1.000 57.10027  ? 79  GLY A N    1 
ATOM   1192 C CA   . GLY A 1 79  ? -3.25011  24.10071  -5.40642  1.000 52.10614  ? 79  GLY A CA   1 
ATOM   1193 C C    . GLY A 1 79  ? -3.22306  22.64376  -5.80360  1.000 52.85639  ? 79  GLY A C    1 
ATOM   1194 O O    . GLY A 1 79  ? -3.62599  22.28592  -6.91510  1.000 50.91753  ? 79  GLY A O    1 
ATOM   1195 H H    . GLY A 1 79  ? -2.46760  24.57017  -7.14665  1.000 68.51409  ? 79  GLY A H    1 
ATOM   1196 H HA2  . GLY A 1 79  ? -2.61543  24.23725  -4.68570  1.000 62.52114  ? 79  GLY A HA2  1 
ATOM   1197 H HA3  . GLY A 1 79  ? -4.14031  24.31885  -5.08885  1.000 62.52114  ? 79  GLY A HA3  1 
ATOM   1198 N N    . HIS A 1 80  ? -2.72927  21.79806  -4.90469  1.000 50.90579  ? 80  HIS A N    1 
ATOM   1199 C CA   . HIS A 1 80  ? -2.66441  20.36380  -5.13140  1.000 53.97263  ? 80  HIS A CA   1 
ATOM   1200 C C    . HIS A 1 80  ? -2.97141  19.65094  -3.82471  1.000 53.47507  ? 80  HIS A C    1 
ATOM   1201 O O    . HIS A 1 80  ? -2.49493  20.05475  -2.76028  1.000 48.14729  ? 80  HIS A O    1 
ATOM   1202 C CB   . HIS A 1 80  ? -1.28970  19.93613  -5.66727  1.000 55.72262  ? 80  HIS A CB   1 
ATOM   1203 C CG   . HIS A 1 80  ? -0.15606  20.20765  -4.72709  1.000 58.53732  ? 80  HIS A CG   1 
ATOM   1204 N ND1  . HIS A 1 80  ? 0.43563   21.44724  -4.61190  1.000 54.76091  ? 80  HIS A ND1  1 
ATOM   1205 C CD2  . HIS A 1 80  ? 0.50383   19.39503  -3.86769  1.000 57.59283  ? 80  HIS A CD2  1 
ATOM   1206 C CE1  . HIS A 1 80  ? 1.40748   21.38795  -3.71872  1.000 57.77062  ? 80  HIS A CE1  1 
ATOM   1207 N NE2  . HIS A 1 80  ? 1.47012   20.15372  -3.25253  1.000 62.82806  ? 80  HIS A NE2  1 
ATOM   1208 H H    . HIS A 1 80  ? -2.41938  22.03895  -4.13949  1.000 61.08072  ? 80  HIS A H    1 
ATOM   1209 H HA   . HIS A 1 80  ? -3.32811  20.10049  -5.78795  1.000 64.76093  ? 80  HIS A HA   1 
ATOM   1210 H HB2  . HIS A 1 80  ? -1.30690  18.98185  -5.84034  1.000 66.86091  ? 80  HIS A HB2  1 
ATOM   1211 H HB3  . HIS A 1 80  ? -1.11277  20.41929  -6.48955  1.000 66.86091  ? 80  HIS A HB3  1 
ATOM   1212 H HD1  . HIS A 1 80  ? 0.20777   22.14968  -5.05265  1.000 65.70687  ? 80  HIS A HD1  1 
ATOM   1213 H HD2  . HIS A 1 80  ? 0.33456   18.49235  -3.72134  1.000 69.10516  ? 80  HIS A HD2  1 
ATOM   1214 H HE1  . HIS A 1 80  ? 1.95439   22.09497  -3.46197  1.000 69.31851  ? 80  HIS A HE1  1 
ATOM   1215 N N    . SER A 1 81  ? -3.77982  18.59861  -3.91545  1.000 48.00922  ? 81  SER A N    1 
ATOM   1216 C CA   . SER A 1 81  ? -4.19377  17.81764  -2.76057  1.000 39.40098  ? 81  SER A CA   1 
ATOM   1217 C C    . SER A 1 81  ? -4.21740  16.34875  -3.15641  1.000 51.68095  ? 81  SER A C    1 
ATOM   1218 O O    . SER A 1 81  ? -4.23628  16.00503  -4.34129  1.000 51.64048  ? 81  SER A O    1 
ATOM   1219 C CB   . SER A 1 81  ? -5.56868  18.27298  -2.25035  1.000 38.89701  ? 81  SER A CB   1 
ATOM   1220 O OG   . SER A 1 81  ? -6.02909  17.45778  -1.18888  1.000 57.91043  ? 81  SER A OG   1 
ATOM   1221 H H    . SER A 1 81  ? -4.10931  18.31152  -4.65614  1.000 57.60483  ? 81  SER A H    1 
ATOM   1222 H HA   . SER A 1 81  ? -3.55894  17.92157  -2.03456  1.000 47.27495  ? 81  SER A HA   1 
ATOM   1223 H HB2  . SER A 1 81  ? -5.49734  19.18711  -1.93385  1.000 46.67018  ? 81  SER A HB2  1 
ATOM   1224 H HB3  . SER A 1 81  ? -6.20498  18.22351  -2.98081  1.000 46.67018  ? 81  SER A HB3  1 
ATOM   1225 H HG   . SER A 1 81  ? -6.81657  17.66814  -0.98581  1.000 69.48629  ? 81  SER A HG   1 
ATOM   1226 N N    . MET A 1 82  ? -4.21076  15.48025  -2.14744  1.000 48.46554  ? 82  MET A N    1 
ATOM   1227 C CA   . MET A 1 82  ? -4.23517  14.03927  -2.35772  1.000 36.67553  ? 82  MET A CA   1 
ATOM   1228 C C    . MET A 1 82  ? -5.35737  13.44121  -1.52612  1.000 47.81846  ? 82  MET A C    1 
ATOM   1229 O O    . MET A 1 82  ? -5.39893  13.62883  -0.30556  1.000 53.34675  ? 82  MET A O    1 
ATOM   1230 C CB   . MET A 1 82  ? -2.89690  13.40385  -1.98212  1.000 42.58580  ? 82  MET A CB   1 
ATOM   1231 C CG   . MET A 1 82  ? -2.55883  12.17649  -2.80608  1.000 41.57523  ? 82  MET A CG   1 
ATOM   1232 S SD   . MET A 1 82  ? -1.39858  11.05777  -1.99946  1.000 51.25480  ? 82  MET A SD   1 
ATOM   1233 C CE   . MET A 1 82  ? -2.42373  10.42172  -0.66847  1.000 68.90233  ? 82  MET A CE   1 
ATOM   1234 H H    . MET A 1 82  ? -4.19193  15.70812  -1.31839  1.000 58.15242  ? 82  MET A H    1 
ATOM   1235 H HA   . MET A 1 82  ? -4.40407  13.85982  -3.29590  1.000 44.00441  ? 82  MET A HA   1 
ATOM   1236 H HB2  . MET A 1 82  ? -2.19186  14.05620  -2.11725  1.000 51.09673  ? 82  MET A HB2  1 
ATOM   1237 H HB3  . MET A 1 82  ? -2.92782  13.13704  -1.05004  1.000 51.09673  ? 82  MET A HB3  1 
ATOM   1238 H HG2  . MET A 1 82  ? -3.37513  11.68180  -2.97880  1.000 49.88405  ? 82  MET A HG2  1 
ATOM   1239 H HG3  . MET A 1 82  ? -2.16069  12.46231  -3.64315  1.000 49.88405  ? 82  MET A HG3  1 
ATOM   1240 H HE1  . MET A 1 82  ? -1.85542  10.17709  0.07858   1.000 82.67657  ? 82  MET A HE1  1 
ATOM   1241 H HE2  . MET A 1 82  ? -3.05032  11.11017  -0.39586  1.000 82.67657  ? 82  MET A HE2  1 
ATOM   1242 H HE3  . MET A 1 82  ? -2.90611  9.64244   -0.98618  1.000 82.67657  ? 82  MET A HE3  1 
ATOM   1243 N N    . GLN A 1 83  ? -6.26255  12.72858  -2.18660  1.000 48.33077  ? 83  GLN A N    1 
ATOM   1244 C CA   . GLN A 1 83  ? -7.36729  12.03422  -1.53492  1.000 40.49766  ? 83  GLN A CA   1 
ATOM   1245 C C    . GLN A 1 83  ? -7.27877  10.57437  -1.95191  1.000 41.38543  ? 83  GLN A C    1 
ATOM   1246 O O    . GLN A 1 83  ? -7.47399  10.25090  -3.12812  1.000 39.02678  ? 83  GLN A O    1 
ATOM   1247 C CB   . GLN A 1 83  ? -8.71098  12.64442  -1.92743  1.000 45.66264  ? 83  GLN A CB   1 
ATOM   1248 C CG   . GLN A 1 83  ? -9.91405  12.00307  -1.25744  1.000 44.47280  ? 83  GLN A CG   1 
ATOM   1249 C CD   . GLN A 1 83  ? -11.22230 12.53945  -1.79952  1.000 45.89780  ? 83  GLN A CD   1 
ATOM   1250 O OE1  . GLN A 1 83  ? -11.23430 13.39876  -2.68104  1.000 50.18402  ? 83  GLN A OE1  1 
ATOM   1251 N NE2  . GLN A 1 83  ? -12.33268 12.03309  -1.27799  1.000 53.35042  ? 83  GLN A NE2  1 
ATOM   1252 H H    . GLN A 1 83  ? -6.25760  12.62927  -3.04083  1.000 57.99070  ? 83  GLN A H    1 
ATOM   1253 H HA   . GLN A 1 83  ? -7.28537  12.09840  -0.57052  1.000 48.59096  ? 83  GLN A HA   1 
ATOM   1254 H HB2  . GLN A 1 83  ? -8.70648  13.58352  -1.68458  1.000 54.78894  ? 83  GLN A HB2  1 
ATOM   1255 H HB3  . GLN A 1 83  ? -8.82476  12.55020  -2.88611  1.000 54.78894  ? 83  GLN A HB3  1 
ATOM   1256 H HG2  . GLN A 1 83  ? -9.89213  11.04577  -1.41234  1.000 53.36113  ? 83  GLN A HG2  1 
ATOM   1257 H HG3  . GLN A 1 83  ? -9.88340  12.18587  -0.30531  1.000 53.36113  ? 83  GLN A HG3  1 
ATOM   1258 H HE21 . GLN A 1 83  ? -12.28452 11.43212  -0.66471  1.000 64.01428  ? 83  GLN A HE21 1 
ATOM   1259 H HE22 . GLN A 1 83  ? -13.10037 12.30594  -1.55332  1.000 64.01428  ? 83  GLN A HE22 1 
ATOM   1260 N N    . ASN A 1 84  ? -6.97545  9.69750   -0.99734  1.000 38.18265  ? 84  ASN A N    1 
ATOM   1261 C CA   . ASN A 1 84  ? -6.75757  8.29371   -1.32163  1.000 42.40285  ? 84  ASN A CA   1 
ATOM   1262 C C    . ASN A 1 84  ? -5.75162  8.19508   -2.46548  1.000 43.83721  ? 84  ASN A C    1 
ATOM   1263 O O    . ASN A 1 84  ? -4.61773  8.66467   -2.32967  1.000 41.57172  ? 84  ASN A O    1 
ATOM   1264 C CB   . ASN A 1 84  ? -8.08337  7.61456   -1.66769  1.000 46.69126  ? 84  ASN A CB   1 
ATOM   1265 C CG   . ASN A 1 84  ? -9.11494  7.74572   -0.55564  1.000 41.68897  ? 84  ASN A CG   1 
ATOM   1266 O OD1  . ASN A 1 84  ? -10.28479 8.03452   -0.80857  1.000 44.53858  ? 84  ASN A OD1  1 
ATOM   1267 N ND2  . ASN A 1 84  ? -8.68091  7.54211   0.68225   1.000 35.57421  ? 84  ASN A ND2  1 
ATOM   1268 H H    . ASN A 1 84  ? -6.89128  9.89019   -0.16344  1.000 45.81295  ? 84  ASN A H    1 
ATOM   1269 H HA   . ASN A 1 84  ? -6.39512  7.81743   -0.55828  1.000 50.87719  ? 84  ASN A HA   1 
ATOM   1270 H HB2  . ASN A 1 84  ? -8.44960  8.02359   -2.46736  1.000 56.02329  ? 84  ASN A HB2  1 
ATOM   1271 H HB3  . ASN A 1 84  ? -7.92491  6.66995   -1.82099  1.000 56.02329  ? 84  ASN A HB3  1 
ATOM   1272 H HD21 . ASN A 1 84  ? -9.22571  7.60484   1.34471   1.000 42.68283  ? 84  ASN A HD21 1 
ATOM   1273 H HD22 . ASN A 1 84  ? -7.85492  7.34747   0.82175   1.000 42.68283  ? 84  ASN A HD22 1 
ATOM   1274 N N    . CYS A 1 85  ? -6.14298  7.62023   -3.60372  1.000 41.64783  ? 85  CYS A N    1 
ATOM   1275 C CA   . CYS A 1 85  ? -5.19434  7.37940   -4.68433  1.000 41.79293  ? 85  CYS A CA   1 
ATOM   1276 C C    . CYS A 1 85  ? -5.35579  8.34022   -5.86193  1.000 35.73425  ? 85  CYS A C    1 
ATOM   1277 O O    . CYS A 1 85  ? -4.83895  8.05988   -6.94660  1.000 37.93345  ? 85  CYS A O    1 
ATOM   1278 C CB   . CYS A 1 85  ? -5.29986  5.93099   -5.16913  1.000 38.72388  ? 85  CYS A CB   1 
ATOM   1279 S SG   . CYS A 1 85  ? -4.89402  4.69879   -3.90411  1.000 45.34100  ? 85  CYS A SG   1 
ATOM   1280 H H    . CYS A 1 85  ? -6.94708  7.36406   -3.76925  1.000 49.97117  ? 85  CYS A H    1 
ATOM   1281 H HA   . CYS A 1 85  ? -4.30397  7.52092   -4.32640  1.000 50.14529  ? 85  CYS A HA   1 
ATOM   1282 H HB2  . CYS A 1 85  ? -6.21037  5.76629   -5.46024  1.000 46.46243  ? 85  CYS A HB2  1 
ATOM   1283 H HB3  . CYS A 1 85  ? -4.68682  5.80597   -5.91038  1.000 46.46243  ? 85  CYS A HB3  1 
ATOM   1284 H HG   . CYS A 1 85  ? -4.86485  3.61212   -4.41234  1.000 54.40297  ? 85  CYS A HG   1 
ATOM   1285 N N    . VAL A 1 86  ? -6.02610  9.47932   -5.67851  1.000 35.30360  ? 86  VAL A N    1 
ATOM   1286 C CA   . VAL A 1 86  ? -6.13312  10.48380  -6.73201  1.000 43.57583  ? 86  VAL A CA   1 
ATOM   1287 C C    . VAL A 1 86  ? -5.49948  11.78460  -6.26143  1.000 36.20995  ? 86  VAL A C    1 
ATOM   1288 O O    . VAL A 1 86  ? -5.59530  12.15117  -5.08445  1.000 35.34657  ? 86  VAL A O    1 
ATOM   1289 C CB   . VAL A 1 86  ? -7.58985  10.74477  -7.17990  1.000 43.76390  ? 86  VAL A CB   1 
ATOM   1290 C CG1  . VAL A 1 86  ? -8.17659  9.50571   -7.85201  1.000 48.32942  ? 86  VAL A CG1  1 
ATOM   1291 C CG2  . VAL A 1 86  ? -8.44670  11.20828  -6.01138  1.000 45.35671  ? 86  VAL A CG2  1 
ATOM   1292 H H    . VAL A 1 86  ? -6.42798  9.69102   -4.94826  1.000 42.35809  ? 86  VAL A H    1 
ATOM   1293 H HA   . VAL A 1 86  ? -5.63727  10.14973  -7.49584  1.000 52.28477  ? 86  VAL A HA   1 
ATOM   1294 H HB   . VAL A 1 86  ? -7.59098  11.46025  -7.83488  1.000 52.51046  ? 86  VAL A HB   1 
ATOM   1295 H HG11 . VAL A 1 86  ? -9.11088  9.66919   -8.05519  1.000 57.98908  ? 86  VAL A HG11 1 
ATOM   1296 H HG12 . VAL A 1 86  ? -7.68637  9.32811   -8.66996  1.000 57.98908  ? 86  VAL A HG12 1 
ATOM   1297 H HG13 . VAL A 1 86  ? -8.09659  8.75100   -7.24793  1.000 57.98908  ? 86  VAL A HG13 1 
ATOM   1298 H HG21 . VAL A 1 86  ? -7.91376  11.18741  -5.20117  1.000 54.42183  ? 86  VAL A HG21 1 
ATOM   1299 H HG22 . VAL A 1 86  ? -8.75229  12.11273  -6.18309  1.000 54.42183  ? 86  VAL A HG22 1 
ATOM   1300 H HG23 . VAL A 1 86  ? -9.20762  10.61336  -5.92221  1.000 54.42183  ? 86  VAL A HG23 1 
ATOM   1301 N N    . LEU A 1 87  ? -4.84304  12.47005  -7.19251  1.000 34.90534  ? 87  LEU A N    1 
ATOM   1302 C CA   . LEU A 1 87  ? -4.40095  13.84117  -6.99812  1.000 38.30384  ? 87  LEU A CA   1 
ATOM   1303 C C    . LEU A 1 87  ? -5.51977  14.78457  -7.41902  1.000 39.88980  ? 87  LEU A C    1 
ATOM   1304 O O    . LEU A 1 87  ? -6.10166  14.62366  -8.49718  1.000 40.13420  ? 87  LEU A O    1 
ATOM   1305 C CB   . LEU A 1 87  ? -3.14842  14.13077  -7.82489  1.000 50.34105  ? 87  LEU A CB   1 
ATOM   1306 C CG   . LEU A 1 87  ? -1.81867  14.42219  -7.13105  1.000 50.39944  ? 87  LEU A CG   1 
ATOM   1307 C CD1  . LEU A 1 87  ? -0.81037  14.91037  -8.16730  1.000 50.18675  ? 87  LEU A CD1  1 
ATOM   1308 C CD2  . LEU A 1 87  ? -1.97699  15.43760  -6.02480  1.000 57.21406  ? 87  LEU A CD2  1 
ATOM   1309 H H    . LEU A 1 87  ? -4.63766  12.15206  -7.96472  1.000 41.88018  ? 87  LEU A H    1 
ATOM   1310 H HA   . LEU A 1 87  ? -4.18882  13.98589  -6.06272  1.000 45.95838  ? 87  LEU A HA   1 
ATOM   1311 H HB2  . LEU A 1 87  ? -2.99329  13.35696  -8.38885  1.000 60.40303  ? 87  LEU A HB2  1 
ATOM   1312 H HB3  . LEU A 1 87  ? -3.34133  14.90745  -8.37303  1.000 60.40303  ? 87  LEU A HB3  1 
ATOM   1313 H HG   . LEU A 1 87  ? -1.48961  13.60820  -6.71869  1.000 60.47310  ? 87  LEU A HG   1 
ATOM   1314 H HD11 . LEU A 1 87  ? -0.77369  14.27253  -8.89717  1.000 60.21787  ? 87  LEU A HD11 1 
ATOM   1315 H HD12 . LEU A 1 87  ? -1.09302  15.77690  -8.49916  1.000 60.21787  ? 87  LEU A HD12 1 
ATOM   1316 H HD13 . LEU A 1 87  ? 0.06158   14.98476  -7.74889  1.000 60.21787  ? 87  LEU A HD13 1 
ATOM   1317 H HD21 . LEU A 1 87  ? -2.23886  14.97959  -5.21083  1.000 68.65064  ? 87  LEU A HD21 1 
ATOM   1318 H HD22 . LEU A 1 87  ? -1.13108  15.89293  -5.89063  1.000 68.65064  ? 87  LEU A HD22 1 
ATOM   1319 H HD23 . LEU A 1 87  ? -2.66038  16.07740  -6.27883  1.000 68.65064  ? 87  LEU A HD23 1 
ATOM   1320 N N    . LYS A 1 88  ? -5.81876  15.76155  -6.57162  1.000 49.39328  ? 88  LYS A N    1 
ATOM   1321 C CA   . LYS A 1 88  ? -6.71767  16.85496  -6.91689  1.000 43.90175  ? 88  LYS A CA   1 
ATOM   1322 C C    . LYS A 1 88  ? -5.87640  18.11698  -7.05773  1.000 49.29701  ? 88  LYS A C    1 
ATOM   1323 O O    . LYS A 1 88  ? -5.21841  18.53906  -6.09974  1.000 53.62368  ? 88  LYS A O    1 
ATOM   1324 C CB   . LYS A 1 88  ? -7.81232  17.03325  -5.86439  1.000 47.59109  ? 88  LYS A CB   1 
ATOM   1325 C CG   . LYS A 1 88  ? -8.53519  15.74061  -5.50506  1.000 44.48124  ? 88  LYS A CG   1 
ATOM   1326 C CD   . LYS A 1 88  ? -10.00137 15.97648  -5.15866  1.000 49.14122  ? 88  LYS A CD   1 
ATOM   1327 C CE   . LYS A 1 88  ? -10.18434 16.57697  -3.77465  1.000 54.34495  ? 88  LYS A CE   1 
ATOM   1328 N NZ   . LYS A 1 88  ? -9.69726  15.66397  -2.70391  1.000 63.45010  ? 88  LYS A NZ   1 
ATOM   1329 H H    . LYS A 1 88  ? -5.50568  15.81355  -5.77232  1.000 59.26571  ? 88  LYS A H    1 
ATOM   1330 H HA   . LYS A 1 88  ? -7.15834  16.67221  -7.76147  1.000 52.67587  ? 88  LYS A HA   1 
ATOM   1331 H HB2  . LYS A 1 88  ? -7.41118  17.38341  -5.05361  1.000 57.10308  ? 88  LYS A HB2  1 
ATOM   1332 H HB3  . LYS A 1 88  ? -8.47273  17.65725  -6.20406  1.000 57.10308  ? 88  LYS A HB3  1 
ATOM   1333 H HG2  . LYS A 1 88  ? -8.49756  15.13393  -6.26099  1.000 53.37126  ? 88  LYS A HG2  1 
ATOM   1334 H HG3  . LYS A 1 88  ? -8.10416  15.33816  -4.73490  1.000 53.37126  ? 88  LYS A HG3  1 
ATOM   1335 H HD2  . LYS A 1 88  ? -10.38545 16.58926  -5.80510  1.000 58.96323  ? 88  LYS A HD2  1 
ATOM   1336 H HD3  . LYS A 1 88  ? -10.47340 15.12944  -5.18334  1.000 58.96323  ? 88  LYS A HD3  1 
ATOM   1337 H HE2  . LYS A 1 88  ? -9.68388  17.40592  -3.71727  1.000 65.20771  ? 88  LYS A HE2  1 
ATOM   1338 H HE3  . LYS A 1 88  ? -11.12703 16.74735  -3.62233  1.000 65.20771  ? 88  LYS A HE3  1 
ATOM   1339 H HZ1  . LYS A 1 88  ? -10.05989 15.88974  -1.92312  1.000 76.13389  ? 88  LYS A HZ1  1 
ATOM   1340 H HZ2  . LYS A 1 88  ? -9.92177  14.82413  -2.89457  1.000 76.13389  ? 88  LYS A HZ2  1 
ATOM   1341 H HZ3  . LYS A 1 88  ? -8.81140  15.71814  -2.63737  1.000 76.13389  ? 88  LYS A HZ3  1 
ATOM   1342 N N    . LEU A 1 89  ? -5.87192  18.68959  -8.25817  1.000 42.72016  ? 89  LEU A N    1 
ATOM   1343 C CA   . LEU A 1 89  ? -5.14436  19.91444  -8.56048  1.000 46.32171  ? 89  LEU A CA   1 
ATOM   1344 C C    . LEU A 1 89  ? -6.14741  21.02941  -8.81878  1.000 48.01418  ? 89  LEU A C    1 
ATOM   1345 O O    . LEU A 1 89  ? -6.91593  20.96001  -9.78467  1.000 43.58637  ? 89  LEU A O    1 
ATOM   1346 C CB   . LEU A 1 89  ? -4.25010  19.73401  -9.78561  1.000 50.60062  ? 89  LEU A CB   1 
ATOM   1347 C CG   . LEU A 1 89  ? -3.31980  18.52599  -9.83108  1.000 46.84986  ? 89  LEU A CG   1 
ATOM   1348 C CD1  . LEU A 1 89  ? -2.81521  18.32025  -11.25606 1.000 48.06744  ? 89  LEU A CD1  1 
ATOM   1349 C CD2  . LEU A 1 89  ? -2.16185  18.71296  -8.87109  1.000 48.62394  ? 89  LEU A CD2  1 
ATOM   1350 H H    . LEU A 1 89  ? -6.29824  18.37472  -8.93545  1.000 51.25796  ? 89  LEU A H    1 
ATOM   1351 H HA   . LEU A 1 89  ? -4.59185  20.15200  -7.79942  1.000 55.57982  ? 89  LEU A HA   1 
ATOM   1352 H HB2  . LEU A 1 89  ? -4.82701  19.66887  -10.56268 1.000 60.71452  ? 89  LEU A HB2  1 
ATOM   1353 H HB3  . LEU A 1 89  ? -3.68665  20.52046  -9.85572  1.000 60.71452  ? 89  LEU A HB3  1 
ATOM   1354 H HG   . LEU A 1 89  ? -3.80277  17.73033  -9.55805  1.000 56.21360  ? 89  LEU A HG   1 
ATOM   1355 H HD11 . LEU A 1 89  ? -3.57481  18.28759  -11.85842 1.000 57.67470  ? 89  LEU A HD11 1 
ATOM   1356 H HD12 . LEU A 1 89  ? -2.23480  19.05967  -11.49540 1.000 57.67470  ? 89  LEU A HD12 1 
ATOM   1357 H HD13 . LEU A 1 89  ? -2.32268  17.48572  -11.29926 1.000 57.67470  ? 89  LEU A HD13 1 
ATOM   1358 H HD21 . LEU A 1 89  ? -2.50164  18.71267  -7.96255  1.000 58.34250  ? 89  LEU A HD21 1 
ATOM   1359 H HD22 . LEU A 1 89  ? -1.53285  17.98405  -8.98923  1.000 58.34250  ? 89  LEU A HD22 1 
ATOM   1360 H HD23 . LEU A 1 89  ? -1.72727  19.55901  -9.06145  1.000 58.34250  ? 89  LEU A HD23 1 
ATOM   1361 N N    . LYS A 1 90  ? -6.13090  22.05636  -7.97215  1.000 51.34369  ? 90  LYS A N    1 
ATOM   1362 C CA   . LYS A 1 90  ? -6.96465  23.22775  -8.19967  1.000 47.74210  ? 90  LYS A CA   1 
ATOM   1363 C C    . LYS A 1 90  ? -6.34559  24.10187  -9.28143  1.000 44.55322  ? 90  LYS A C    1 
ATOM   1364 O O    . LYS A 1 90  ? -5.13681  24.35021  -9.28383  1.000 44.78587  ? 90  LYS A O    1 
ATOM   1365 C CB   . LYS A 1 90  ? -7.13793  24.03719  -6.91583  1.000 52.77618  ? 90  LYS A CB   1 
ATOM   1366 C CG   . LYS A 1 90  ? -8.11500  25.19174  -7.06653  1.000 50.80781  ? 90  LYS A CG   1 
ATOM   1367 C CD   . LYS A 1 90  ? -8.31483  25.94905  -5.76634  1.000 65.62453  ? 90  LYS A CD   1 
ATOM   1368 C CE   . LYS A 1 90  ? -9.30802  27.09011  -5.94506  1.000 82.22607  ? 90  LYS A CE   1 
ATOM   1369 N NZ   . LYS A 1 90  ? -9.42886  27.93393  -4.72079  1.000 89.63286  ? 90  LYS A NZ   1 
ATOM   1370 H H    . LYS A 1 90  ? -5.64694  22.09680  -7.26240  1.000 61.60620  ? 90  LYS A H    1 
ATOM   1371 H HA   . LYS A 1 90  ? -7.84561  22.94259  -8.48864  1.000 57.28429  ? 90  LYS A HA   1 
ATOM   1372 H HB2  . LYS A 1 90  ? -7.47181  23.45208  -6.21792  1.000 63.32519  ? 90  LYS A HB2  1 
ATOM   1373 H HB3  . LYS A 1 90  ? -6.27826  24.40478  -6.65749  1.000 63.32519  ? 90  LYS A HB3  1 
ATOM   1374 H HG2  . LYS A 1 90  ? -7.77373  25.81339  -7.72834  1.000 60.96315  ? 90  LYS A HG2  1 
ATOM   1375 H HG3  . LYS A 1 90  ? -8.97584  24.84555  -7.34937  1.000 60.96315  ? 90  LYS A HG3  1 
ATOM   1376 H HD2  . LYS A 1 90  ? -8.65997  25.34498  -5.09041  1.000 78.74321  ? 90  LYS A HD2  1 
ATOM   1377 H HD3  . LYS A 1 90  ? -7.46775  26.32225  -5.47639  1.000 78.74321  ? 90  LYS A HD3  1 
ATOM   1378 H HE2  . LYS A 1 90  ? -9.01254  27.65744  -6.67425  1.000 98.66505  ? 90  LYS A HE2  1 
ATOM   1379 H HE3  . LYS A 1 90  ? -10.18283 26.72173  -6.14483  1.000 98.66505  ? 90  LYS A HE3  1 
ATOM   1380 H HZ1  . LYS A 1 90  ? -8.61994  28.14388  -4.41474  1.000 107.55320 ? 90  LYS A HZ1  1 
ATOM   1381 H HZ2  . LYS A 1 90  ? -9.86960  28.68360  -4.91008  1.000 107.55320 ? 90  LYS A HZ2  1 
ATOM   1382 H HZ3  . LYS A 1 90  ? -9.87101  27.49084  -4.08812  1.000 107.55320 ? 90  LYS A HZ3  1 
ATOM   1383 N N    . VAL A 1 91  ? -7.18422  24.57109  -10.20090 1.000 50.58383  ? 91  VAL A N    1 
ATOM   1384 C CA   . VAL A 1 91  ? -6.73483  25.34916  -11.34495 1.000 47.09097  ? 91  VAL A CA   1 
ATOM   1385 C C    . VAL A 1 91  ? -7.40389  26.71606  -11.30103 1.000 45.65187  ? 91  VAL A C    1 
ATOM   1386 O O    . VAL A 1 91  ? -8.42607  26.91713  -10.64074 1.000 48.76350  ? 91  VAL A O    1 
ATOM   1387 C CB   . VAL A 1 91  ? -7.02865  24.62944  -12.67773 1.000 46.26325  ? 91  VAL A CB   1 
ATOM   1388 C CG1  . VAL A 1 91  ? -5.99159  23.54149  -12.92242 1.000 44.11495  ? 91  VAL A CG1  1 
ATOM   1389 C CG2  . VAL A 1 91  ? -8.43473  24.03729  -12.66805 1.000 39.84984  ? 91  VAL A CG2  1 
ATOM   1390 H H    . VAL A 1 91  ? -8.03513  24.44797  -10.18118 1.000 60.69437  ? 91  VAL A H    1 
ATOM   1391 H HA   . VAL A 1 91  ? -5.77703  25.48966  -11.28360 1.000 56.50293  ? 91  VAL A HA   1 
ATOM   1392 H HB   . VAL A 1 91  ? -6.97911  25.27134  -13.40327 1.000 55.50967  ? 91  VAL A HB   1 
ATOM   1393 H HG11 . VAL A 1 91  ? -6.39227  22.83755  -13.45611 1.000 52.93171  ? 91  VAL A HG11 1 
ATOM   1394 H HG12 . VAL A 1 91  ? -5.23641  23.92555  -13.39475 1.000 52.93171  ? 91  VAL A HG12 1 
ATOM   1395 H HG13 . VAL A 1 91  ? -5.70090  23.18453  -12.06862 1.000 52.93171  ? 91  VAL A HG13 1 
ATOM   1396 H HG21 . VAL A 1 91  ? -8.68340  23.79926  -13.57491 1.000 47.81358  ? 91  VAL A HG21 1 
ATOM   1397 H HG22 . VAL A 1 91  ? -8.44083  23.24731  -12.10521 1.000 47.81358  ? 91  VAL A HG22 1 
ATOM   1398 H HG23 . VAL A 1 91  ? -9.05307  24.69761  -12.31801 1.000 47.81358  ? 91  VAL A HG23 1 
ATOM   1399 N N    . ASP A 1 92  ? -6.79836  27.66910  -12.01094 1.000 45.76042  ? 92  ASP A N    1 
ATOM   1400 C CA   . ASP A 1 92  ? -7.29811  29.03661  -12.03551 1.000 53.10553  ? 92  ASP A CA   1 
ATOM   1401 C C    . ASP A 1 92  ? -8.51929  29.20581  -12.92772 1.000 57.19337  ? 92  ASP A C    1 
ATOM   1402 O O    . ASP A 1 92  ? -9.10746  30.29240  -12.94312 1.000 63.11049  ? 92  ASP A O    1 
ATOM   1403 C CB   . ASP A 1 92  ? -6.20096  29.99086  -12.51374 1.000 53.60499  ? 92  ASP A CB   1 
ATOM   1404 C CG   . ASP A 1 92  ? -6.05888  30.00102  -14.02224 1.000 62.99937  ? 92  ASP A CG   1 
ATOM   1405 O OD1  . ASP A 1 92  ? -5.85007  28.91754  -14.60959 1.000 67.01444  ? 92  ASP A OD1  1 
ATOM   1406 O OD2  . ASP A 1 92  ? -6.17510  31.09101  -14.62239 1.000 71.59891  ? 92  ASP A OD2  1 
ATOM   1407 H H    . ASP A 1 92  ? -6.09348  27.54509  -12.48777 1.000 54.90627  ? 92  ASP A H    1 
ATOM   1408 H HA   . ASP A 1 92  ? -7.54554  29.28560  -11.13126 1.000 63.72041  ? 92  ASP A HA   1 
ATOM   1409 H HB2  . ASP A 1 92  ? -6.41635  30.89166  -12.22553 1.000 64.31976  ? 92  ASP A HB2  1 
ATOM   1410 H HB3  . ASP A 1 92  ? -5.35250  29.71476  -12.13325 1.000 64.31976  ? 92  ASP A HB3  1 
ATOM   1411 N N    . THR A 1 93  ? -8.91289  28.16769  -13.66181 1.000 53.11363  ? 93  THR A N    1 
ATOM   1412 C CA   . THR A 1 93  ? -9.98311  28.25522  -14.64499 1.000 61.05277  ? 93  THR A CA   1 
ATOM   1413 C C    . THR A 1 93  ? -10.95435 27.10307  -14.44559 1.000 55.40128  ? 93  THR A C    1 
ATOM   1414 O O    . THR A 1 93  ? -10.54533 25.93770  -14.42382 1.000 53.30685  ? 93  THR A O    1 
ATOM   1415 C CB   . THR A 1 93  ? -9.41613  28.22557  -16.07059 1.000 57.65035  ? 93  THR A CB   1 
ATOM   1416 O OG1  . THR A 1 93  ? -8.61926  29.39563  -16.29304 1.000 68.06739  ? 93  THR A OG1  1 
ATOM   1417 C CG2  . THR A 1 93  ? -10.53158 28.16881  -17.09749 1.000 49.69722  ? 93  THR A CG2  1 
ATOM   1418 H H    . THR A 1 93  ? -8.56471  27.38338  -13.60502 1.000 63.73012  ? 93  THR A H    1 
ATOM   1419 H HA   . THR A 1 93  ? -10.47120 29.08380  -14.51803 1.000 73.25709  ? 93  THR A HA   1 
ATOM   1420 H HB   . THR A 1 93  ? -8.86755  27.43329  -16.18124 1.000 69.17420  ? 93  THR A HB   1 
ATOM   1421 H HG1  . THR A 1 93  ? -8.01276  29.44454  -15.71393 1.000 81.67464  ? 93  THR A HG1  1 
ATOM   1422 H HG21 . THR A 1 93  ? -10.91277 27.27725  -17.12432 1.000 59.63044  ? 93  THR A HG21 1 
ATOM   1423 H HG22 . THR A 1 93  ? -11.22857 28.80232  -16.86559 1.000 59.63044  ? 93  THR A HG22 1 
ATOM   1424 H HG23 . THR A 1 93  ? -10.18513 28.38963  -17.97619 1.000 59.63044  ? 93  THR A HG23 1 
ATOM   1425 N N    . ALA A 1 94  ? -12.23400 27.43014  -14.29238 1.000 54.88583  ? 94  ALA A N    1 
ATOM   1426 C CA   . ALA A 1 94  ? -13.27131 26.41122  -14.26897 1.000 52.25124  ? 94  ALA A CA   1 
ATOM   1427 C C    . ALA A 1 94  ? -13.51816 25.91713  -15.68669 1.000 53.45803  ? 94  ALA A C    1 
ATOM   1428 O O    . ALA A 1 94  ? -13.54721 26.70369  -16.63667 1.000 53.42753  ? 94  ALA A O    1 
ATOM   1429 C CB   . ALA A 1 94  ? -14.56370 26.96391  -13.67048 1.000 44.74525  ? 94  ALA A CB   1 
ATOM   1430 H H    . ALA A 1 94  ? -12.52461 28.23429  -14.20031 1.000 65.85677  ? 94  ALA A H    1 
ATOM   1431 H HA   . ALA A 1 94  ? -12.99247 25.66546  -13.71490 1.000 62.69527  ? 94  ALA A HA   1 
ATOM   1432 H HB1  . ALA A 1 94  ? -15.22272 26.25324  -13.63119 1.000 53.68807  ? 94  ALA A HB1  1 
ATOM   1433 H HB2  . ALA A 1 94  ? -14.38151 27.29582  -12.77743 1.000 53.68807  ? 94  ALA A HB2  1 
ATOM   1434 H HB3  . ALA A 1 94  ? -14.88834 27.68541  -14.23168 1.000 53.68807  ? 94  ALA A HB3  1 
ATOM   1435 N N    . ASN A 1 95  ? -13.67806 24.61022  -15.83080 1.000 46.03712  ? 95  ASN A N    1 
ATOM   1436 C CA   . ASN A 1 95  ? -13.93534 24.03374  -17.14331 1.000 51.53333  ? 95  ASN A CA   1 
ATOM   1437 C C    . ASN A 1 95  ? -15.28528 24.51311  -17.66287 1.000 50.14914  ? 95  ASN A C    1 
ATOM   1438 O O    . ASN A 1 95  ? -16.32131 24.08540  -17.14495 1.000 51.80630  ? 95  ASN A O    1 
ATOM   1439 C CB   . ASN A 1 95  ? -13.91401 22.50728  -17.06476 1.000 50.35706  ? 95  ASN A CB   1 
ATOM   1440 C CG   . ASN A 1 95  ? -14.08683 21.85194  -18.42020 1.000 50.54735  ? 95  ASN A CG   1 
ATOM   1441 O OD1  . ASN A 1 95  ? -14.05151 22.51782  -19.45661 1.000 53.18698  ? 95  ASN A OD1  1 
ATOM   1442 N ND2  . ASN A 1 95  ? -14.26975 20.53648  -18.41982 1.000 50.96320  ? 95  ASN A ND2  1 
ATOM   1443 H H    . ASN A 1 95  ? -13.64256 24.03890  -15.18899 1.000 55.23832  ? 95  ASN A H    1 
ATOM   1444 H HA   . ASN A 1 95  ? -13.24739 24.32127  -17.76375 1.000 61.83377  ? 95  ASN A HA   1 
ATOM   1445 H HB2  . ASN A 1 95  ? -13.06261 22.22086  -16.69874 1.000 60.42225  ? 95  ASN A HB2  1 
ATOM   1446 H HB3  . ASN A 1 95  ? -14.63826 22.20946  -16.49234 1.000 60.42225  ? 95  ASN A HB3  1 
ATOM   1447 H HD21 . ASN A 1 95  ? -14.37295 20.11648  -19.16316 1.000 61.14961  ? 95  ASN A HD21 1 
ATOM   1448 H HD22 . ASN A 1 95  ? -14.28500 20.10467  -17.67624 1.000 61.14961  ? 95  ASN A HD22 1 
ATOM   1449 N N    . PRO A 1 96  ? -15.32875 25.38447  -18.67808 1.000 44.36870  ? 96  PRO A N    1 
ATOM   1450 C CA   . PRO A 1 96  ? -16.63642 25.84845  -19.17487 1.000 58.14635  ? 96  PRO A CA   1 
ATOM   1451 C C    . PRO A 1 96  ? -17.50124 24.73066  -19.73423 1.000 58.49077  ? 96  PRO A C    1 
ATOM   1452 O O    . PRO A 1 96  ? -18.72015 24.91214  -19.85466 1.000 45.46978  ? 96  PRO A O    1 
ATOM   1453 C CB   . PRO A 1 96  ? -16.26001 26.87096  -20.25791 1.000 45.88069  ? 96  PRO A CB   1 
ATOM   1454 C CG   . PRO A 1 96  ? -14.89549 26.45581  -20.71215 1.000 51.58902  ? 96  PRO A CG   1 
ATOM   1455 C CD   . PRO A 1 96  ? -14.21198 25.90118  -19.49045 1.000 48.58148  ? 96  PRO A CD   1 
ATOM   1456 H HA   . PRO A 1 96  ? -17.12128 26.30235  -18.46791 1.000 69.76939  ? 96  PRO A HA   1 
ATOM   1457 H HB2  . PRO A 1 96  ? -16.89751 26.83069  -20.98789 1.000 55.05060  ? 96  PRO A HB2  1 
ATOM   1458 H HB3  . PRO A 1 96  ? -16.24464 27.76408  -19.87976 1.000 55.05060  ? 96  PRO A HB3  1 
ATOM   1459 H HG2  . PRO A 1 96  ? -14.97151 25.77787  -21.40173 1.000 61.90060  ? 96  PRO A HG2  1 
ATOM   1460 H HG3  . PRO A 1 96  ? -14.41568 27.22580  -21.05537 1.000 61.90060  ? 96  PRO A HG3  1 
ATOM   1461 H HD2  . PRO A 1 96  ? -13.60160 25.18684  -19.73139 1.000 58.29155  ? 96  PRO A HD2  1 
ATOM   1462 H HD3  . PRO A 1 96  ? -13.73458 26.59946  -19.01569 1.000 58.29155  ? 96  PRO A HD3  1 
ATOM   1463 N N    . LYS A 1 97  ? -16.91643 23.58112  -20.07104 1.000 49.29557  ? 97  LYS A N    1 
ATOM   1464 C CA   . LYS A 1 97  ? -17.66077 22.45161  -20.60650 1.000 46.79004  ? 97  LYS A CA   1 
ATOM   1465 C C    . LYS A 1 97  ? -18.04940 21.44769  -19.53151 1.000 47.17904  ? 97  LYS A C    1 
ATOM   1466 O O    . LYS A 1 97  ? -18.46054 20.33065  -19.86325 1.000 48.69417  ? 97  LYS A O    1 
ATOM   1467 C CB   . LYS A 1 97  ? -16.84811 21.74664  -21.69431 1.000 46.58358  ? 97  LYS A CB   1 
ATOM   1468 C CG   . LYS A 1 97  ? -16.24556 22.68264  -22.72161 1.000 47.02561  ? 97  LYS A CG   1 
ATOM   1469 C CD   . LYS A 1 97  ? -15.88269 21.94729  -24.00118 1.000 46.67502  ? 97  LYS A CD   1 
ATOM   1470 C CE   . LYS A 1 97  ? -17.01789 22.00351  -25.01667 1.000 67.79326  ? 97  LYS A CE   1 
ATOM   1471 N NZ   . LYS A 1 97  ? -17.36422 23.40580  -25.39946 1.000 68.90468  ? 97  LYS A NZ   1 
ATOM   1472 H H    . LYS A 1 97  ? -16.07274 23.43251  -19.99549 1.000 59.14846  ? 97  LYS A H    1 
ATOM   1473 H HA   . LYS A 1 97  ? -18.47417 22.79034  -21.01213 1.000 56.14182  ? 97  LYS A HA   1 
ATOM   1474 H HB2  . LYS A 1 97  ? -16.12009 21.26307  -21.27355 1.000 55.89406  ? 97  LYS A HB2  1 
ATOM   1475 H HB3  . LYS A 1 97  ? -17.42926 21.12830  -22.16423 1.000 55.89406  ? 97  LYS A HB3  1 
ATOM   1476 H HG2  . LYS A 1 97  ? -16.88779 23.37592  -22.94024 1.000 56.42450  ? 97  LYS A HG2  1 
ATOM   1477 H HG3  . LYS A 1 97  ? -15.43842 23.08040  -22.35938 1.000 56.42450  ? 97  LYS A HG3  1 
ATOM   1478 H HD2  . LYS A 1 97  ? -15.09844 22.35854  -24.39708 1.000 56.00380  ? 97  LYS A HD2  1 
ATOM   1479 H HD3  . LYS A 1 97  ? -15.70179 21.01646  -23.79691 1.000 56.00380  ? 97  LYS A HD3  1 
ATOM   1480 H HE2  . LYS A 1 97  ? -16.75106 21.52846  -25.81919 1.000 81.34568  ? 97  LYS A HE2  1 
ATOM   1481 H HE3  . LYS A 1 97  ? -17.80804 21.59091  -24.63415 1.000 81.34568  ? 97  LYS A HE3  1 
ATOM   1482 H HZ1  . LYS A 1 97  ? -17.84037 23.78915  -24.75260 1.000 82.67939  ? 97  LYS A HZ1  1 
ATOM   1483 H HZ2  . LYS A 1 97  ? -16.62122 23.87808  -25.52984 1.000 82.67939  ? 97  LYS A HZ2  1 
ATOM   1484 H HZ3  . LYS A 1 97  ? -17.84273 23.40714  -26.14988 1.000 82.67939  ? 97  LYS A HZ3  1 
ATOM   1485 N N    . THR A 1 98  ? -17.91715 21.81024  -18.26049 1.000 43.40541  ? 98  THR A N    1 
ATOM   1486 C CA   . THR A 1 98  ? -18.28856 20.90811  -17.18178 1.000 45.20621  ? 98  THR A CA   1 
ATOM   1487 C C    . THR A 1 98  ? -19.74730 20.50008  -17.34535 1.000 50.00176  ? 98  THR A C    1 
ATOM   1488 O O    . THR A 1 98  ? -20.62572 21.37708  -17.37042 1.000 45.20911  ? 98  THR A O    1 
ATOM   1489 C CB   . THR A 1 98  ? -18.09816 21.55758  -15.81302 1.000 46.30705  ? 98  THR A CB   1 
ATOM   1490 O OG1  . THR A 1 98  ? -16.76793 22.07080  -15.69500 1.000 47.28727  ? 98  THR A OG1  1 
ATOM   1491 C CG2  . THR A 1 98  ? -18.34822 20.53960  -14.70540 1.000 47.09323  ? 98  THR A CG2  1 
ATOM   1492 H H    . THR A 1 98  ? -17.61533 22.57175  -17.99855 1.000 52.08026  ? 98  THR A H    1 
ATOM   1493 H HA   . THR A 1 98  ? -17.71470 20.12705  -17.22067 1.000 54.24122  ? 98  THR A HA   1 
ATOM   1494 H HB   . THR A 1 98  ? -18.72923 22.28734  -15.71258 1.000 55.56223  ? 98  THR A HB   1 
ATOM   1495 H HG1  . THR A 1 98  ? -16.64938 22.69163  -16.24827 1.000 56.73850  ? 98  THR A HG1  1 
ATOM   1496 H HG21 . THR A 1 98  ? -18.16620 20.93904  -13.84041 1.000 56.50565  ? 98  THR A HG21 1 
ATOM   1497 H HG22 . THR A 1 98  ? -19.27213 20.24501  -14.72796 1.000 56.50565  ? 98  THR A HG22 1 
ATOM   1498 H HG23 . THR A 1 98  ? -17.76953 19.77036  -14.82496 1.000 56.50565  ? 98  THR A HG23 1 
ATOM   1499 N N    . PRO A 1 99  ? -20.05601 19.21435  -17.46564 1.000 48.25703  ? 99  PRO A N    1 
ATOM   1500 C CA   . PRO A 1 99  ? -21.45358 18.78915  -17.50053 1.000 37.13658  ? 99  PRO A CA   1 
ATOM   1501 C C    . PRO A 1 99  ? -22.00472 18.61022  -16.08872 1.000 44.26173  ? 99  PRO A C    1 
ATOM   1502 O O    . PRO A 1 99  ? -21.26710 18.57460  -15.10439 1.000 42.99573  ? 99  PRO A O    1 
ATOM   1503 C CB   . PRO A 1 99  ? -21.39014 17.44623  -18.23586 1.000 38.63081  ? 99  PRO A CB   1 
ATOM   1504 C CG   . PRO A 1 99  ? -20.05172 16.88863  -17.83678 1.000 53.47254  ? 99  PRO A CG   1 
ATOM   1505 C CD   . PRO A 1 99  ? -19.12979 18.08112  -17.66844 1.000 40.33750  ? 99  PRO A CD   1 
ATOM   1506 H HA   . PRO A 1 99  ? -22.00451 19.41150  -18.00058 1.000 44.55767  ? 99  PRO A HA   1 
ATOM   1507 H HB2  . PRO A 1 99  ? -22.11334 16.86917  -17.94450 1.000 46.35074  ? 99  PRO A HB2  1 
ATOM   1508 H HB3  . PRO A 1 99  ? -21.44231 17.58528  -19.19442 1.000 46.35074  ? 99  PRO A HB3  1 
ATOM   1509 H HG2  . PRO A 1 99  ? -20.13739 16.40173  -17.00222 1.000 64.16082  ? 99  PRO A HG2  1 
ATOM   1510 H HG3  . PRO A 1 99  ? -19.72401 16.29826  -18.53318 1.000 64.16082  ? 99  PRO A HG3  1 
ATOM   1511 H HD2  . PRO A 1 99  ? -18.55498 17.96466  -16.89583 1.000 48.39877  ? 99  PRO A HD2  1 
ATOM   1512 H HD3  . PRO A 1 99  ? -18.59226 18.21496  -18.46471 1.000 48.39877  ? 99  PRO A HD3  1 
ATOM   1513 N N    . LYS A 1 100 ? -23.32741 18.51651  -16.01445 1.000 46.77176  ? 100 LYS A N    1 
ATOM   1514 C CA   . LYS A 1 100 ? -23.95854 17.98191  -14.81686 1.000 51.82673  ? 100 LYS A CA   1 
ATOM   1515 C C    . LYS A 1 100 ? -23.34020 16.62649  -14.51140 1.000 51.20624  ? 100 LYS A C    1 
ATOM   1516 O O    . LYS A 1 100 ? -23.27341 15.75659  -15.38455 1.000 49.79689  ? 100 LYS A O    1 
ATOM   1517 C CB   . LYS A 1 100 ? -25.46645 17.84507  -15.02649 1.000 53.16355  ? 100 LYS A CB   1 
ATOM   1518 C CG   . LYS A 1 100 ? -26.31376 18.80594  -14.20853 1.000 61.49987  ? 100 LYS A CG   1 
ATOM   1519 C CD   . LYS A 1 100 ? -27.56584 19.22310  -14.97075 1.000 59.73108  ? 100 LYS A CD   1 
ATOM   1520 C CE   . LYS A 1 100 ? -27.24133 20.27007  -16.02746 1.000 61.47705  ? 100 LYS A CE   1 
ATOM   1521 N NZ   . LYS A 1 100 ? -28.44108 20.69493  -16.80195 1.000 69.86500  ? 100 LYS A NZ   1 
ATOM   1522 H H    . LYS A 1 100 ? -23.87357 18.75252  -16.63543 1.000 56.11988  ? 100 LYS A H    1 
ATOM   1523 H HA   . LYS A 1 100 ? -23.82702 18.58148  -14.06579 1.000 62.18585  ? 100 LYS A HA   1 
ATOM   1524 H HB2  . LYS A 1 100 ? -25.66298 18.00717  -15.96244 1.000 63.79003  ? 100 LYS A HB2  1 
ATOM   1525 H HB3  . LYS A 1 100 ? -25.73041 16.94392  -14.78330 1.000 63.79003  ? 100 LYS A HB3  1 
ATOM   1526 H HG2  . LYS A 1 100 ? -26.58703 18.37340  -13.38443 1.000 73.79362  ? 100 LYS A HG2  1 
ATOM   1527 H HG3  . LYS A 1 100 ? -25.79696 19.60234  -14.00965 1.000 73.79362  ? 100 LYS A HG3  1 
ATOM   1528 H HD2  . LYS A 1 100 ? -27.94720 18.44883  -15.41343 1.000 71.67106  ? 100 LYS A HD2  1 
ATOM   1529 H HD3  . LYS A 1 100 ? -28.20944 19.60177  -14.35165 1.000 71.67106  ? 100 LYS A HD3  1 
ATOM   1530 H HE2  . LYS A 1 100 ? -26.87133 21.05444  -15.59299 1.000 73.76623  ? 100 LYS A HE2  1 
ATOM   1531 H HE3  . LYS A 1 100 ? -26.59658 19.90118  -16.65125 1.000 73.76623  ? 100 LYS A HE3  1 
ATOM   1532 H HZ1  . LYS A 1 100 ? -29.05236 21.03703  -16.25294 1.000 83.83177  ? 100 LYS A HZ1  1 
ATOM   1533 H HZ2  . LYS A 1 100 ? -28.21353 21.31215  -17.40143 1.000 83.83177  ? 100 LYS A HZ2  1 
ATOM   1534 H HZ3  . LYS A 1 100 ? -28.79272 19.99603  -17.22620 1.000 83.83177  ? 100 LYS A HZ3  1 
ATOM   1535 N N    . TYR A 1 101 ? -22.86310 16.45192  -13.28183 1.000 48.53102  ? 101 TYR A N    1 
ATOM   1536 C CA   . TYR A 1 101 ? -22.14153 15.23191  -12.95938 1.000 47.25959  ? 101 TYR A CA   1 
ATOM   1537 C C    . TYR A 1 101 ? -22.28893 14.88613  -11.48663 1.000 47.04276  ? 101 TYR A C    1 
ATOM   1538 O O    . TYR A 1 101 ? -22.50656 15.75664  -10.63997 1.000 43.87451  ? 101 TYR A O    1 
ATOM   1539 C CB   . TYR A 1 101 ? -20.65196 15.35646  -13.32290 1.000 52.83444  ? 101 TYR A CB   1 
ATOM   1540 C CG   . TYR A 1 101 ? -19.84121 16.25756  -12.40670 1.000 48.69703  ? 101 TYR A CG   1 
ATOM   1541 C CD1  . TYR A 1 101 ? -19.69721 17.61190  -12.67952 1.000 52.04524  ? 101 TYR A CD1  1 
ATOM   1542 C CD2  . TYR A 1 101 ? -19.20331 15.74837  -11.28071 1.000 50.55052  ? 101 TYR A CD2  1 
ATOM   1543 C CE1  . TYR A 1 101 ? -18.95188 18.43792  -11.85262 1.000 43.07336  ? 101 TYR A CE1  1 
ATOM   1544 C CE2  . TYR A 1 101 ? -18.45717 16.56976  -10.44423 1.000 45.07255  ? 101 TYR A CE2  1 
ATOM   1545 C CZ   . TYR A 1 101 ? -18.33537 17.91317  -10.73802 1.000 50.28321  ? 101 TYR A CZ   1 
ATOM   1546 O OH   . TYR A 1 101 ? -17.59450 18.73521  -9.91706  1.000 47.76263  ? 101 TYR A OH   1 
ATOM   1547 H H    . TYR A 1 101 ? -22.94389 17.01311  -12.63520 1.000 58.23099  ? 101 TYR A H    1 
ATOM   1548 H HA   . TYR A 1 101 ? -22.53591 14.50149  -13.46122 1.000 56.70528  ? 101 TYR A HA   1 
ATOM   1549 H HB2  . TYR A 1 101 ? -20.25280 14.47303  -13.28964 1.000 63.39511  ? 101 TYR A HB2  1 
ATOM   1550 H HB3  . TYR A 1 101 ? -20.58406 15.71762  -14.22059 1.000 63.39511  ? 101 TYR A HB3  1 
ATOM   1551 H HD1  . TYR A 1 101 ? -20.10898 17.97162  -13.43182 1.000 62.44806  ? 101 TYR A HD1  1 
ATOM   1552 H HD2  . TYR A 1 101 ? -19.27736 14.84241  -11.08411 1.000 60.65439  ? 101 TYR A HD2  1 
ATOM   1553 H HE1  . TYR A 1 101 ? -18.86836 19.34298  -12.04958 1.000 51.68181  ? 101 TYR A HE1  1 
ATOM   1554 H HE2  . TYR A 1 101 ? -18.04217 16.21644  -9.69068  1.000 54.08083  ? 101 TYR A HE2  1 
ATOM   1555 H HH   . TYR A 1 101 ? -17.33958 18.30989  -9.23903  1.000 57.30893  ? 101 TYR A HH   1 
ATOM   1556 N N    . LYS A 1 102 ? -22.18961 13.58708  -11.20908 1.000 44.84829  ? 102 LYS A N    1 
ATOM   1557 C CA   . LYS A 1 102 ? -22.04673 13.02968  -9.87585  1.000 43.37135  ? 102 LYS A CA   1 
ATOM   1558 C C    . LYS A 1 102 ? -20.78803 12.16886  -9.85808  1.000 37.81628  ? 102 LYS A C    1 
ATOM   1559 O O    . LYS A 1 102 ? -20.27365 11.77200  -10.90720 1.000 42.71892  ? 102 LYS A O    1 
ATOM   1560 C CB   . LYS A 1 102 ? -23.25306 12.15995  -9.47242  1.000 49.03461  ? 102 LYS A CB   1 
ATOM   1561 C CG   . LYS A 1 102 ? -24.62627 12.64734  -9.92428  1.000 64.09419  ? 102 LYS A CG   1 
ATOM   1562 C CD   . LYS A 1 102 ? -25.70285 11.61348  -9.56303  1.000 67.25716  ? 102 LYS A CD   1 
ATOM   1563 C CE   . LYS A 1 102 ? -27.05898 11.93120  -10.18827 1.000 75.30046  ? 102 LYS A CE   1 
ATOM   1564 N NZ   . LYS A 1 102 ? -28.05352 12.46229  -9.20511  1.000 76.90190  ? 102 LYS A NZ   1 
ATOM   1565 H H    . LYS A 1 102 ? -22.20382 12.97734  -11.81540 1.000 53.81172  ? 102 LYS A H    1 
ATOM   1566 H HA   . LYS A 1 102 ? -21.97679 13.74886  -9.22870  1.000 52.03940  ? 102 LYS A HA   1 
ATOM   1567 H HB2  . LYS A 1 102 ? -23.12661 11.27582  -9.85088  1.000 58.83530  ? 102 LYS A HB2  1 
ATOM   1568 H HB3  . LYS A 1 102 ? -23.27499 12.10631  -8.50415  1.000 58.83530  ? 102 LYS A HB3  1 
ATOM   1569 H HG2  . LYS A 1 102 ? -24.83785 13.48338  -9.48024  1.000 76.90680  ? 102 LYS A HG2  1 
ATOM   1570 H HG3  . LYS A 1 102 ? -24.62738 12.77298  -10.88611 1.000 76.90680  ? 102 LYS A HG3  1 
ATOM   1571 H HD2  . LYS A 1 102 ? -25.42325 10.74083  -9.88116  1.000 80.70237  ? 102 LYS A HD2  1 
ATOM   1572 H HD3  . LYS A 1 102 ? -25.81390 11.59544  -8.59958  1.000 80.70237  ? 102 LYS A HD3  1 
ATOM   1573 H HE2  . LYS A 1 102 ? -26.93726 12.60077  -10.87947 1.000 90.35432  ? 102 LYS A HE2  1 
ATOM   1574 H HE3  . LYS A 1 102 ? -27.42541 11.11977  -10.57325 1.000 90.35432  ? 102 LYS A HE3  1 
ATOM   1575 H HZ1  . LYS A 1 102 ? -28.81565 12.66034  -9.61990  1.000 92.27605  ? 102 LYS A HZ1  1 
ATOM   1576 H HZ2  . LYS A 1 102 ? -28.21628 11.85278  -8.57734  1.000 92.27605  ? 102 LYS A HZ2  1 
ATOM   1577 H HZ3  . LYS A 1 102 ? -27.73577 13.19797  -8.81793  1.000 92.27605  ? 102 LYS A HZ3  1 
ATOM   1578 N N    . PHE A 1 103 ? -20.29072 11.88803  -8.65702  1.000 38.57088  ? 103 PHE A N    1 
ATOM   1579 C CA   . PHE A 1 103 ? -19.31512 10.82875  -8.42552  1.000 36.03168  ? 103 PHE A CA   1 
ATOM   1580 C C    . PHE A 1 103 ? -20.05186 9.68983   -7.73000  1.000 40.61382  ? 103 PHE A C    1 
ATOM   1581 O O    . PHE A 1 103 ? -20.66091 9.90030   -6.67517  1.000 41.63749  ? 103 PHE A O    1 
ATOM   1582 C CB   . PHE A 1 103 ? -18.14114 11.30211  -7.56499  1.000 40.27218  ? 103 PHE A CB   1 
ATOM   1583 C CG   . PHE A 1 103 ? -17.19133 12.24667  -8.26259  1.000 37.75040  ? 103 PHE A CG   1 
ATOM   1584 C CD1  . PHE A 1 103 ? -17.30882 12.51580  -9.61519  1.000 37.36809  ? 103 PHE A CD1  1 
ATOM   1585 C CD2  . PHE A 1 103 ? -16.16882 12.85971  -7.55016  1.000 38.07695  ? 103 PHE A CD2  1 
ATOM   1586 C CE1  . PHE A 1 103 ? -16.43778 13.37784  -10.24101 1.000 40.65409  ? 103 PHE A CE1  1 
ATOM   1587 C CE2  . PHE A 1 103 ? -15.29008 13.72420  -8.17255  1.000 39.95380  ? 103 PHE A CE2  1 
ATOM   1588 C CZ   . PHE A 1 103 ? -15.42546 13.98535  -9.52086  1.000 46.48000  ? 103 PHE A CZ   1 
ATOM   1589 H H    . PHE A 1 103 ? -20.51020 12.31020  -7.94064  1.000 46.27882  ? 103 PHE A H    1 
ATOM   1590 H HA   . PHE A 1 103 ? -18.94863 10.52900  -9.27212  1.000 43.23178  ? 103 PHE A HA   1 
ATOM   1591 H HB2  . PHE A 1 103 ? -18.49415 11.76321  -6.78803  1.000 48.32039  ? 103 PHE A HB2  1 
ATOM   1592 H HB3  . PHE A 1 103 ? -17.63002 10.52617  -7.28646  1.000 48.32039  ? 103 PHE A HB3  1 
ATOM   1593 H HD1  . PHE A 1 103 ? -17.98498 12.10889  -10.10726 1.000 44.83548  ? 103 PHE A HD1  1 
ATOM   1594 H HD2  . PHE A 1 103 ? -16.07464 12.68562  -6.64147  1.000 45.68611  ? 103 PHE A HD2  1 
ATOM   1595 H HE1  . PHE A 1 103 ? -16.53001 13.55222  -11.14984 1.000 48.77868  ? 103 PHE A HE1  1 
ATOM   1596 H HE2  . PHE A 1 103 ? -14.60950 14.12897  -7.68484  1.000 47.93834  ? 103 PHE A HE2  1 
ATOM   1597 H HZ   . PHE A 1 103 ? -14.83740 14.56839  -9.94412  1.000 55.76977  ? 103 PHE A HZ   1 
ATOM   1598 N N    . VAL A 1 104 ? -20.00773 8.49691   -8.31807  1.000 37.42547  ? 104 VAL A N    1 
ATOM   1599 C CA   . VAL A 1 104 ? -20.69385 7.33645   -7.76614  1.000 39.21440  ? 104 VAL A CA   1 
ATOM   1600 C C    . VAL A 1 104 ? -19.70663 6.18340   -7.67206  1.000 33.70502  ? 104 VAL A C    1 
ATOM   1601 O O    . VAL A 1 104 ? -18.72113 6.12141   -8.41280  1.000 41.33390  ? 104 VAL A O    1 
ATOM   1602 C CB   . VAL A 1 104 ? -21.92319 6.92715   -8.61338  1.000 37.45688  ? 104 VAL A CB   1 
ATOM   1603 C CG1  . VAL A 1 104 ? -22.63774 8.16024   -9.14600  1.000 37.19879  ? 104 VAL A CG1  1 
ATOM   1604 C CG2  . VAL A 1 104 ? -21.51459 6.00442   -9.75069  1.000 43.78223  ? 104 VAL A CG2  1 
ATOM   1605 H H    . VAL A 1 104 ? -19.58086 8.33486   -9.04685  1.000 44.90433  ? 104 VAL A H    1 
ATOM   1606 H HA   . VAL A 1 104 ? -21.00211 7.55045   -6.87167  1.000 47.05105  ? 104 VAL A HA   1 
ATOM   1607 H HB   . VAL A 1 104 ? -22.54274 6.44090   -8.04716  1.000 44.94203  ? 104 VAL A HB   1 
ATOM   1608 H HG11 . VAL A 1 104 ? -22.05681 8.61427   -9.77630  1.000 44.63233  ? 104 VAL A HG11 1 
ATOM   1609 H HG12 . VAL A 1 104 ? -23.45543 7.88466   -9.58910  1.000 44.63233  ? 104 VAL A HG12 1 
ATOM   1610 H HG13 . VAL A 1 104 ? -22.84593 8.74964   -8.40426  1.000 44.63233  ? 104 VAL A HG13 1 
ATOM   1611 H HG21 . VAL A 1 104 ? -22.22955 5.97460   -10.40555 1.000 52.53245  ? 104 VAL A HG21 1 
ATOM   1612 H HG22 . VAL A 1 104 ? -20.70496 6.34741   -10.16028 1.000 52.53245  ? 104 VAL A HG22 1 
ATOM   1613 H HG23 . VAL A 1 104 ? -21.35466 5.11632   -9.39489  1.000 52.53245  ? 104 VAL A HG23 1 
ATOM   1614 N N    . ARG A 1 105 ? -19.97650 5.26359   -6.75305  1.000 35.78437  ? 105 ARG A N    1 
ATOM   1615 C CA   . ARG A 1 105 ? -19.21263 4.03088   -6.62496  1.000 40.74409  ? 105 ARG A CA   1 
ATOM   1616 C C    . ARG A 1 105 ? -20.14873 2.88977   -6.99340  1.000 37.38296  ? 105 ARG A C    1 
ATOM   1617 O O    . ARG A 1 105 ? -21.15535 2.66729   -6.31159  1.000 40.52550  ? 105 ARG A O    1 
ATOM   1618 C CB   . ARG A 1 105 ? -18.65082 3.85674   -5.21389  1.000 36.58023  ? 105 ARG A CB   1 
ATOM   1619 C CG   . ARG A 1 105 ? -17.74550 2.64684   -5.07037  1.000 38.11415  ? 105 ARG A CG   1 
ATOM   1620 C CD   . ARG A 1 105 ? -17.26765 2.47040   -3.64238  1.000 39.46718  ? 105 ARG A CD   1 
ATOM   1621 N NE   . ARG A 1 105 ? -16.35464 1.34044   -3.51688  1.000 41.46834  ? 105 ARG A NE   1 
ATOM   1622 C CZ   . ARG A 1 105 ? -15.09164 1.35124   -3.92139  1.000 37.83696  ? 105 ARG A CZ   1 
ATOM   1623 N NH1  . ARG A 1 105 ? -14.56033 2.41538   -4.50267  1.000 42.87235  ? 105 ARG A NH1  1 
ATOM   1624 N NH2  . ARG A 1 105 ? -14.34371 0.26677   -3.74049  1.000 35.71490  ? 105 ARG A NH2  1 
ATOM   1625 H H    . ARG A 1 105 ? -20.61305 5.33405   -6.17907  1.000 42.93502  ? 105 ARG A H    1 
ATOM   1626 H HA   . ARG A 1 105 ? -18.45372 4.03658   -7.22905  1.000 48.88667  ? 105 ARG A HA   1 
ATOM   1627 H HB2  . ARG A 1 105 ? -18.13377 4.64438   -4.98328  1.000 43.89005  ? 105 ARG A HB2  1 
ATOM   1628 H HB3  . ARG A 1 105 ? -19.38914 3.75126   -4.59368  1.000 43.89005  ? 105 ARG A HB3  1 
ATOM   1629 H HG2  . ARG A 1 105 ? -18.23328 1.84912   -5.32847  1.000 45.73075  ? 105 ARG A HG2  1 
ATOM   1630 H HG3  . ARG A 1 105 ? -16.96802 2.75897   -5.63945  1.000 45.73075  ? 105 ARG A HG3  1 
ATOM   1631 H HD2  . ARG A 1 105 ? -16.80073 3.27208   -3.35918  1.000 47.35439  ? 105 ARG A HD2  1 
ATOM   1632 H HD3  . ARG A 1 105 ? -18.03138 2.31026   -3.06621  1.000 47.35439  ? 105 ARG A HD3  1 
ATOM   1633 H HE   . ARG A 1 105 ? -16.65494 0.61947   -3.15683  1.000 49.75578  ? 105 ARG A HE   1 
ATOM   1634 H HH11 . ARG A 1 105 ? -15.03645 3.12094   -4.62551  1.000 51.44059  ? 105 ARG A HH11 1 
ATOM   1635 H HH12 . ARG A 1 105 ? -13.73906 2.40111   -4.75744  1.000 51.44059  ? 105 ARG A HH12 1 
ATOM   1636 H HH21 . ARG A 1 105 ? -14.68028 -0.43002  -3.36525  1.000 42.85165  ? 105 ARG A HH21 1 
ATOM   1637 H HH22 . ARG A 1 105 ? -13.52341 0.26218   -3.99874  1.000 42.85165  ? 105 ARG A HH22 1 
ATOM   1638 N N    . ILE A 1 106 ? -19.83510 2.18979   -8.07796  1.000 33.69859  ? 106 ILE A N    1 
ATOM   1639 C CA   . ILE A 1 106 ? -20.73525 1.17522   -8.59934  1.000 34.64259  ? 106 ILE A CA   1 
ATOM   1640 C C    . ILE A 1 106 ? -20.47028 -0.14570  -7.89118  1.000 38.98585  ? 106 ILE A C    1 
ATOM   1641 O O    . ILE A 1 106 ? -19.38982 -0.38897  -7.34829  1.000 43.79552  ? 106 ILE A O    1 
ATOM   1642 C CB   . ILE A 1 106 ? -20.61021 1.01934   -10.12960 1.000 38.09563  ? 106 ILE A CB   1 
ATOM   1643 C CG1  . ILE A 1 106 ? -19.16671 0.70866   -10.53024 1.000 37.33033  ? 106 ILE A CG1  1 
ATOM   1644 C CG2  . ILE A 1 106 ? -21.12304 2.27724   -10.82752 1.000 38.21272  ? 106 ILE A CG2  1 
ATOM   1645 C CD1  . ILE A 1 106 ? -19.01136 0.32703   -11.98908 1.000 36.28577  ? 106 ILE A CD1  1 
ATOM   1646 H H    . ILE A 1 106 ? -19.10793 2.28532   -8.52706  1.000 40.43208  ? 106 ILE A H    1 
ATOM   1647 H HA   . ILE A 1 106 ? -21.64608 1.44478   -8.40284  1.000 41.56488  ? 106 ILE A HA   1 
ATOM   1648 H HB   . ILE A 1 106 ? -21.15717 0.26889   -10.40986 1.000 45.70853  ? 106 ILE A HB   1 
ATOM   1649 H HG12 . ILE A 1 106 ? -18.62154 1.49466   -10.36933 1.000 44.79017  ? 106 ILE A HG12 1 
ATOM   1650 H HG13 . ILE A 1 106 ? -18.84606 -0.03303  -9.99360  1.000 44.79017  ? 106 ILE A HG13 1 
ATOM   1651 H HG21 . ILE A 1 106 ? -20.60161 3.03880   -10.52912 1.000 45.84904  ? 106 ILE A HG21 1 
ATOM   1652 H HG22 . ILE A 1 106 ? -21.02857 2.16704   -11.78660 1.000 45.84904  ? 106 ILE A HG22 1 
ATOM   1653 H HG23 . ILE A 1 106 ? -22.05706 2.40622   -10.59979 1.000 45.84904  ? 106 ILE A HG23 1 
ATOM   1654 H HD11 . ILE A 1 106 ? -18.11756 -0.02219  -12.13071 1.000 43.53670  ? 106 ILE A HD11 1 
ATOM   1655 H HD12 . ILE A 1 106 ? -19.66989 -0.34996  -12.21027 1.000 43.53670  ? 106 ILE A HD12 1 
ATOM   1656 H HD13 . ILE A 1 106 ? -19.14955 1.11474   -12.53801 1.000 43.53670  ? 106 ILE A HD13 1 
ATOM   1657 N N    . GLN A 1 107 ? -21.48770 -1.00020  -7.88540  1.000 44.03799  ? 107 GLN A N    1 
ATOM   1658 C CA   . GLN A 1 107 ? -21.40168 -2.35555  -7.37055  1.000 46.64933  ? 107 GLN A CA   1 
ATOM   1659 C C    . GLN A 1 107 ? -20.95115 -3.29940  -8.47428  1.000 38.24211  ? 107 GLN A C    1 
ATOM   1660 O O    . GLN A 1 107 ? -21.03280 -2.96902  -9.66060  1.000 40.94205  ? 107 GLN A O    1 
ATOM   1661 C CB   . GLN A 1 107 ? -22.76004 -2.80104  -6.83158  1.000 48.69922  ? 107 GLN A CB   1 
ATOM   1662 C CG   . GLN A 1 107 ? -23.38466 -1.85542  -5.80981  1.000 50.49249  ? 107 GLN A CG   1 
ATOM   1663 C CD   . GLN A 1 107 ? -22.64628 -1.84531  -4.48387  1.000 72.17108  ? 107 GLN A CD   1 
ATOM   1664 O OE1  . GLN A 1 107 ? -21.99002 -2.82189  -4.11711  1.000 77.49327  ? 107 GLN A OE1  1 
ATOM   1665 N NE2  . GLN A 1 107 ? -22.74943 -0.73566  -3.75662  1.000 76.38832  ? 107 GLN A NE2  1 
ATOM   1666 H H    . GLN A 1 107 ? -22.26971 -0.80815  -8.18737  1.000 52.83936  ? 107 GLN A H    1 
ATOM   1667 H HA   . GLN A 1 107 ? -20.76229 -2.39355  -6.64210  1.000 55.97297  ? 107 GLN A HA   1 
ATOM   1668 H HB2  . GLN A 1 107 ? -23.37735 -2.87493  -7.57614  1.000 58.43284  ? 107 GLN A HB2  1 
ATOM   1669 H HB3  . GLN A 1 107 ? -22.65280 -3.66439  -6.40260  1.000 58.43284  ? 107 GLN A HB3  1 
ATOM   1670 H HG2  . GLN A 1 107 ? -23.37205 -0.95330  -6.16607  1.000 60.58476  ? 107 GLN A HG2  1 
ATOM   1671 H HG3  . GLN A 1 107 ? -24.29873 -2.13271  -5.64104  1.000 60.58476  ? 107 GLN A HG3  1 
ATOM   1672 H HE21 . GLN A 1 107 ? -23.21615 -0.07378  -4.04591  1.000 91.65975  ? 107 GLN A HE21 1 
ATOM   1673 H HE22 . GLN A 1 107 ? -22.34937 -0.68042  -2.99735  1.000 91.65975  ? 107 GLN A HE22 1 
ATOM   1674 N N    . PRO A 1 108 ? -20.46483 -4.48749  -8.12546  1.000 40.59083  ? 108 PRO A N    1 
ATOM   1675 C CA   . PRO A 1 108 ? -20.06780 -5.43765  -9.16911  1.000 38.93267  ? 108 PRO A CA   1 
ATOM   1676 C C    . PRO A 1 108 ? -21.26687 -5.84575  -10.01049 1.000 40.70457  ? 108 PRO A C    1 
ATOM   1677 O O    . PRO A 1 108 ? -22.39891 -5.92234  -9.52820  1.000 41.07135  ? 108 PRO A O    1 
ATOM   1678 C CB   . PRO A 1 108 ? -19.49072 -6.61929  -8.37926  1.000 42.49691  ? 108 PRO A CB   1 
ATOM   1679 C CG   . PRO A 1 108 ? -19.09182 -6.02989  -7.05637  1.000 47.60524  ? 108 PRO A CG   1 
ATOM   1680 C CD   . PRO A 1 108 ? -20.12672 -4.97794  -6.77804  1.000 43.54595  ? 108 PRO A CD   1 
ATOM   1681 H HA   . PRO A 1 108 ? -19.37562 -5.06879  -9.73984  1.000 46.71298  ? 108 PRO A HA   1 
ATOM   1682 H HB2  . PRO A 1 108 ? -20.16743 -7.30492  -8.26580  1.000 50.99006  ? 108 PRO A HB2  1 
ATOM   1683 H HB3  . PRO A 1 108 ? -18.72205 -6.98550  -8.84395  1.000 50.99006  ? 108 PRO A HB3  1 
ATOM   1684 H HG2  . PRO A 1 108 ? -19.10122 -6.71644  -6.37119  1.000 57.12006  ? 108 PRO A HG2  1 
ATOM   1685 H HG3  . PRO A 1 108 ? -18.20685 -5.63810  -7.12132  1.000 57.12006  ? 108 PRO A HG3  1 
ATOM   1686 H HD2  . PRO A 1 108 ? -20.90408 -5.36229  -6.34343  1.000 52.24891  ? 108 PRO A HD2  1 
ATOM   1687 H HD3  . PRO A 1 108 ? -19.75934 -4.26571  -6.23154  1.000 52.24891  ? 108 PRO A HD3  1 
ATOM   1688 N N    . GLY A 1 109 ? -21.00725 -6.09481  -11.29090 1.000 37.17351  ? 109 GLY A N    1 
ATOM   1689 C CA   . GLY A 1 109 ? -22.04586 -6.41672  -12.23649 1.000 39.59803  ? 109 GLY A CA   1 
ATOM   1690 C C    . GLY A 1 109 ? -22.63010 -5.22675  -12.96565 1.000 37.10983  ? 109 GLY A C    1 
ATOM   1691 O O    . GLY A 1 109 ? -23.27449 -5.41056  -14.00605 1.000 37.10706  ? 109 GLY A O    1 
ATOM   1692 H H    . GLY A 1 109 ? -20.21857 -6.08081  -11.63352 1.000 44.60198  ? 109 GLY A H    1 
ATOM   1693 H HA2  . GLY A 1 109 ? -21.68395 -7.02311  -12.90148 1.000 47.51141  ? 109 GLY A HA2  1 
ATOM   1694 H HA3  . GLY A 1 109 ? -22.76891 -6.85967  -11.76543 1.000 47.51141  ? 109 GLY A HA3  1 
ATOM   1695 N N    . GLN A 1 110 ? -22.43484 -4.01600  -12.45014 1.000 36.02976  ? 110 GLN A N    1 
ATOM   1696 C CA   . GLN A 1 110 ? -22.89729 -2.82071  -13.13902 1.000 36.86617  ? 110 GLN A CA   1 
ATOM   1697 C C    . GLN A 1 110 ? -21.91525 -2.44755  -14.24184 1.000 39.80534  ? 110 GLN A C    1 
ATOM   1698 O O    . GLN A 1 110 ? -20.70135 -2.62895  -14.10547 1.000 35.13452  ? 110 GLN A O    1 
ATOM   1699 C CB   . GLN A 1 110 ? -23.07629 -1.66218  -12.15427 1.000 31.70234  ? 110 GLN A CB   1 
ATOM   1700 C CG   . GLN A 1 110 ? -24.47980 -1.61306  -11.54180 1.000 56.79994  ? 110 GLN A CG   1 
ATOM   1701 C CD   . GLN A 1 110 ? -24.62391 -0.60091  -10.41004 1.000 57.97958  ? 110 GLN A CD   1 
ATOM   1702 O OE1  . GLN A 1 110 ? -23.64048 -0.19488  -9.78787  1.000 48.22171  ? 110 GLN A OE1  1 
ATOM   1703 N NE2  . GLN A 1 110 ? -25.86215 -0.19261  -10.13848 1.000 70.74995  ? 110 GLN A NE2  1 
ATOM   1704 H H    . GLN A 1 110 ? -22.03726 -3.86238  -11.70319 1.000 43.22949  ? 110 GLN A H    1 
ATOM   1705 H HA   . GLN A 1 110 ? -23.76220 -2.98716  -13.54537 1.000 44.23317  ? 110 GLN A HA   1 
ATOM   1706 H HB2  . GLN A 1 110 ? -22.43693 -1.76110  -11.43155 1.000 38.03658  ? 110 GLN A HB2  1 
ATOM   1707 H HB3  . GLN A 1 110 ? -22.92307 -0.82553  -12.62058 1.000 38.03658  ? 110 GLN A HB3  1 
ATOM   1708 H HG2  . GLN A 1 110 ? -25.11437 -1.37310  -12.23508 1.000 68.15370  ? 110 GLN A HG2  1 
ATOM   1709 H HG3  . GLN A 1 110 ? -24.69472 -2.48866  -11.18398 1.000 68.15370  ? 110 GLN A HG3  1 
ATOM   1710 H HE21 . GLN A 1 110 ? -26.52526 -0.49927  -10.59218 1.000 84.89371  ? 110 GLN A HE21 1 
ATOM   1711 H HE22 . GLN A 1 110 ? -25.99862 0.37772   -9.50943  1.000 84.89371  ? 110 GLN A HE22 1 
ATOM   1712 N N    . THR A 1 111 ? -22.45393 -1.93923  -15.34284 1.000 35.23408  ? 111 THR A N    1 
ATOM   1713 C CA   . THR A 1 111 ? -21.68190 -1.62099  -16.53220 1.000 32.92384  ? 111 THR A CA   1 
ATOM   1714 C C    . THR A 1 111 ? -21.44478 -0.11792  -16.61751 1.000 32.23091  ? 111 THR A C    1 
ATOM   1715 O O    . THR A 1 111 ? -22.06222 0.67855   -15.90733 1.000 30.92809  ? 111 THR A O    1 
ATOM   1716 C CB   . THR A 1 111 ? -22.40895 -2.12031  -17.78613 1.000 31.74471  ? 111 THR A CB   1 
ATOM   1717 O OG1  . THR A 1 111 ? -23.72023 -1.54479  -17.83817 1.000 29.15196  ? 111 THR A OG1  1 
ATOM   1718 C CG2  . THR A 1 111 ? -22.53082 -3.64183  -17.77180 1.000 39.46618  ? 111 THR A CG2  1 
ATOM   1719 H H    . THR A 1 111 ? -23.29194 -1.76483  -15.42610 1.000 42.27466  ? 111 THR A H    1 
ATOM   1720 H HA   . THR A 1 111 ? -20.81984 -2.06324  -16.48559 1.000 39.50238  ? 111 THR A HA   1 
ATOM   1721 H HB   . THR A 1 111 ? -21.90520 -1.86203  -18.57380 1.000 38.08742  ? 111 THR A HB   1 
ATOM   1722 H HG1  . THR A 1 111 ? -24.13759 -1.71632  -17.12966 1.000 34.97612  ? 111 THR A HG1  1 
ATOM   1723 H HG21 . THR A 1 111 ? -23.19171 -3.92785  -18.42166 1.000 47.35319  ? 111 THR A HG21 1 
ATOM   1724 H HG22 . THR A 1 111 ? -21.67681 -4.04515  -17.99292 1.000 47.35319  ? 111 THR A HG22 1 
ATOM   1725 H HG23 . THR A 1 111 ? -22.80341 -3.94454  -16.89148 1.000 47.35319  ? 111 THR A HG23 1 
ATOM   1726 N N    . PHE A 1 112 ? -20.53231 0.26574   -17.50498 1.000 33.46233  ? 112 PHE A N    1 
ATOM   1727 C CA   . PHE A 1 112 ? -20.24079 1.67524   -17.72364 1.000 32.70130  ? 112 PHE A CA   1 
ATOM   1728 C C    . PHE A 1 112 ? -19.39618 1.81276   -18.98006 1.000 33.70453  ? 112 PHE A C    1 
ATOM   1729 O O    . PHE A 1 112 ? -18.79137 0.84719   -19.45508 1.000 31.49746  ? 112 PHE A O    1 
ATOM   1730 C CB   . PHE A 1 112 ? -19.52365 2.29473   -16.51806 1.000 32.16278  ? 112 PHE A CB   1 
ATOM   1731 C CG   . PHE A 1 112 ? -18.27155 1.57004   -16.11924 1.000 30.19237  ? 112 PHE A CG   1 
ATOM   1732 C CD1  . PHE A 1 112 ? -18.31892 0.52615   -15.21211 1.000 35.34784  ? 112 PHE A CD1  1 
ATOM   1733 C CD2  . PHE A 1 112 ? -17.04659 1.93201   -16.65220 1.000 32.25106  ? 112 PHE A CD2  1 
ATOM   1734 C CE1  . PHE A 1 112 ? -17.16411 -0.14664  -14.84245 1.000 34.00380  ? 112 PHE A CE1  1 
ATOM   1735 C CE2  . PHE A 1 112 ? -15.88947 1.26933   -16.28438 1.000 37.27870  ? 112 PHE A CE2  1 
ATOM   1736 C CZ   . PHE A 1 112 ? -15.94896 0.22667   -15.37958 1.000 35.34481  ? 112 PHE A CZ   1 
ATOM   1737 H H    . PHE A 1 112 ? -20.06989 -0.27180  -17.99162 1.000 40.14857  ? 112 PHE A H    1 
ATOM   1738 H HA   . PHE A 1 112 ? -21.07118 2.15557   -17.86733 1.000 39.23533  ? 112 PHE A HA   1 
ATOM   1739 H HB2  . PHE A 1 112 ? -19.28010 3.20803   -16.73591 1.000 38.58911  ? 112 PHE A HB2  1 
ATOM   1740 H HB3  . PHE A 1 112 ? -20.12619 2.28435   -15.75798 1.000 38.58911  ? 112 PHE A HB3  1 
ATOM   1741 H HD1  . PHE A 1 112 ? -19.13532 0.27266   -14.84585 1.000 42.41118  ? 112 PHE A HD1  1 
ATOM   1742 H HD2  . PHE A 1 112 ? -17.00087 2.62969   -17.26543 1.000 38.69505  ? 112 PHE A HD2  1 
ATOM   1743 H HE1  . PHE A 1 112 ? -17.20843 -0.84823  -14.23360 1.000 40.79833  ? 112 PHE A HE1  1 
ATOM   1744 H HE2  . PHE A 1 112 ? -15.07179 1.52543   -16.64591 1.000 44.72822  ? 112 PHE A HE2  1 
ATOM   1745 H HZ   . PHE A 1 112 ? -15.17252 -0.22211  -15.13334 1.000 42.40754  ? 112 PHE A HZ   1 
ATOM   1746 N N    . SER A 1 113 ? -19.37126 3.02863   -19.51351 1.000 38.41720  ? 113 SER A N    1 
ATOM   1747 C CA   . SER A 1 113 ? -18.56719 3.34392   -20.68202 1.000 31.20467  ? 113 SER A CA   1 
ATOM   1748 C C    . SER A 1 113 ? -17.20702 3.85973   -20.24001 1.000 36.85505  ? 113 SER A C    1 
ATOM   1749 O O    . SER A 1 113 ? -17.10975 4.65340   -19.30162 1.000 33.20992  ? 113 SER A O    1 
ATOM   1750 C CB   . SER A 1 113 ? -19.26721 4.38759   -21.55053 1.000 29.70484  ? 113 SER A CB   1 
ATOM   1751 O OG   . SER A 1 113 ? -20.40758 3.83461   -22.17523 1.000 35.56116  ? 113 SER A OG   1 
ATOM   1752 H H    . SER A 1 113 ? -19.81934 3.69717   -19.21039 1.000 46.09442  ? 113 SER A H    1 
ATOM   1753 H HA   . SER A 1 113 ? -18.43827 2.54646   -21.21899 1.000 37.43938  ? 113 SER A HA   1 
ATOM   1754 H HB2  . SER A 1 113 ? -19.54212 5.13119   -20.99162 1.000 35.63958  ? 113 SER A HB2  1 
ATOM   1755 H HB3  . SER A 1 113 ? -18.65086 4.69579   -22.23318 1.000 35.63958  ? 113 SER A HB3  1 
ATOM   1756 H HG   . SER A 1 113 ? -20.19311 3.14767   -22.60849 1.000 42.66717  ? 113 SER A HG   1 
ATOM   1757 N N    . VAL A 1 114 ? -16.15802 3.38906   -20.90985 1.000 30.50610  ? 114 VAL A N    1 
ATOM   1758 C CA   . VAL A 1 114 ? -14.79686 3.86217   -20.69144 1.000 31.16335  ? 114 VAL A CA   1 
ATOM   1759 C C    . VAL A 1 114 ? -14.37160 4.68602   -21.89796 1.000 31.34364  ? 114 VAL A C    1 
ATOM   1760 O O    . VAL A 1 114 ? -14.54796 4.25966   -23.04652 1.000 27.52775  ? 114 VAL A O    1 
ATOM   1761 C CB   . VAL A 1 114 ? -13.82032 2.69785   -20.45406 1.000 37.33419  ? 114 VAL A CB   1 
ATOM   1762 C CG1  . VAL A 1 114 ? -12.38129 3.16149   -20.66518 1.000 28.41667  ? 114 VAL A CG1  1 
ATOM   1763 C CG2  . VAL A 1 114 ? -14.00060 2.14591   -19.04820 1.000 35.10366  ? 114 VAL A CG2  1 
ATOM   1764 H H    . VAL A 1 114 ? -16.21341 2.77806   -21.51253 1.000 36.60110  ? 114 VAL A H    1 
ATOM   1765 H HA   . VAL A 1 114 ? -14.78516 4.43496   -19.90871 1.000 37.38979  ? 114 VAL A HA   1 
ATOM   1766 H HB   . VAL A 1 114 ? -14.00670 1.98922   -21.08968 1.000 44.79479  ? 114 VAL A HB   1 
ATOM   1767 H HG11 . VAL A 1 114 ? -12.30226 4.08549   -20.38080 1.000 34.09378  ? 114 VAL A HG11 1 
ATOM   1768 H HG12 . VAL A 1 114 ? -11.78879 2.60172   -20.13934 1.000 34.09378  ? 114 VAL A HG12 1 
ATOM   1769 H HG13 . VAL A 1 114 ? -12.15973 3.08499   -21.60644 1.000 34.09378  ? 114 VAL A HG13 1 
ATOM   1770 H HG21 . VAL A 1 114 ? -13.69115 1.22683   -19.02767 1.000 42.11816  ? 114 VAL A HG21 1 
ATOM   1771 H HG22 . VAL A 1 114 ? -13.48225 2.68337   -18.42905 1.000 42.11816  ? 114 VAL A HG22 1 
ATOM   1772 H HG23 . VAL A 1 114 ? -14.94070 2.18376   -18.81221 1.000 42.11816  ? 114 VAL A HG23 1 
ATOM   1773 N N    . LEU A 1 115 ? -13.81994 5.86761   -21.63106 1.000 31.05993  ? 115 LEU A N    1 
ATOM   1774 C CA   . LEU A 1 115 ? -13.20095 6.71537   -22.64612 1.000 29.82225  ? 115 LEU A CA   1 
ATOM   1775 C C    . LEU A 1 115 ? -11.68756 6.58092   -22.49415 1.000 32.42077  ? 115 LEU A C    1 
ATOM   1776 O O    . LEU A 1 115 ? -11.07858 7.23272   -21.64186 1.000 31.07376  ? 115 LEU A O    1 
ATOM   1777 C CB   . LEU A 1 115 ? -13.65050 8.16347   -22.49007 1.000 31.26166  ? 115 LEU A CB   1 
ATOM   1778 C CG   . LEU A 1 115 ? -13.08769 9.14591   -23.51914 1.000 28.01835  ? 115 LEU A CG   1 
ATOM   1779 C CD1  . LEU A 1 115 ? -13.57125 8.79024   -24.91012 1.000 30.83776  ? 115 LEU A CD1  1 
ATOM   1780 C CD2  . LEU A 1 115 ? -13.46409 10.57569  -23.16210 1.000 37.05693  ? 115 LEU A CD2  1 
ATOM   1781 H H    . LEU A 1 115 ? -13.79127 6.21059   -20.84293 1.000 37.26569  ? 115 LEU A H    1 
ATOM   1782 H HA   . LEU A 1 115 ? -13.45868 6.40976   -23.52990 1.000 35.78047  ? 115 LEU A HA   1 
ATOM   1783 H HB2  . LEU A 1 115 ? -14.61734 8.19101   -22.56324 1.000 37.50777  ? 115 LEU A HB2  1 
ATOM   1784 H HB3  . LEU A 1 115 ? -13.37515 8.47428   -21.61344 1.000 37.50777  ? 115 LEU A HB3  1 
ATOM   1785 H HG   . LEU A 1 115 ? -12.11946 9.08749   -23.51504 1.000 33.61579  ? 115 LEU A HG   1 
ATOM   1786 H HD11 . LEU A 1 115 ? -13.46639 9.56228   -25.48793 1.000 36.99908  ? 115 LEU A HD11 1 
ATOM   1787 H HD12 . LEU A 1 115 ? -13.04351 8.04992   -25.24824 1.000 36.99908  ? 115 LEU A HD12 1 
ATOM   1788 H HD13 . LEU A 1 115 ? -14.50623 8.53610   -24.86406 1.000 36.99908  ? 115 LEU A HD13 1 
ATOM   1789 H HD21 . LEU A 1 115 ? -13.05170 10.80883  -22.31564 1.000 44.46209  ? 115 LEU A HD21 1 
ATOM   1790 H HD22 . LEU A 1 115 ? -13.14581 11.16966  -23.85981 1.000 44.46209  ? 115 LEU A HD22 1 
ATOM   1791 H HD23 . LEU A 1 115 ? -14.42920 10.63918  -23.08845 1.000 44.46209  ? 115 LEU A HD23 1 
ATOM   1792 N N    . ALA A 1 116 ? -11.08376 5.72582   -23.31688 1.000 30.32797  ? 116 ALA A N    1 
ATOM   1793 C CA   . ALA A 1 116 ? -9.64167  5.51443   -23.26684 1.000 34.21571  ? 116 ALA A CA   1 
ATOM   1794 C C    . ALA A 1 116 ? -8.90504  6.73743   -23.80441 1.000 32.76460  ? 116 ALA A C    1 
ATOM   1795 O O    . ALA A 1 116 ? -9.20733  7.22386   -24.89836 1.000 36.82105  ? 116 ALA A O    1 
ATOM   1796 C CB   . ALA A 1 116 ? -9.26729  4.27367   -24.07721 1.000 32.76124  ? 116 ALA A CB   1 
ATOM   1797 H H    . ALA A 1 116 ? -11.48751 5.25582   -23.91329 1.000 36.38734  ? 116 ALA A H    1 
ATOM   1798 H HA   . ALA A 1 116 ? -9.36793  5.37623   -22.34658 1.000 41.05263  ? 116 ALA A HA   1 
ATOM   1799 H HB1  . ALA A 1 116 ? -8.30948  4.13331   -24.01545 1.000 39.30726  ? 116 ALA A HB1  1 
ATOM   1800 H HB2  . ALA A 1 116 ? -9.73802  3.50647   -23.71568 1.000 39.30726  ? 116 ALA A HB2  1 
ATOM   1801 H HB3  . ALA A 1 116 ? -9.52230  4.41220   -25.00278 1.000 39.30726  ? 116 ALA A HB3  1 
ATOM   1802 N N    . CYS A 1 117 ? -7.92476  7.22803   -23.04351 1.000 34.87754  ? 117 CYS A N    1 
ATOM   1803 C CA   . CYS A 1 117 ? -7.22280  8.45694   -23.38572 1.000 41.03400  ? 117 CYS A CA   1 
ATOM   1804 C C    . CYS A 1 117 ? -5.71645  8.26704   -23.28253 1.000 37.12188  ? 117 CYS A C    1 
ATOM   1805 O O    . CYS A 1 117 ? -5.22561  7.42281   -22.52755 1.000 36.89446  ? 117 CYS A O    1 
ATOM   1806 C CB   . CYS A 1 117 ? -7.65640  9.62440   -22.47671 1.000 39.92905  ? 117 CYS A CB   1 
ATOM   1807 S SG   . CYS A 1 117 ? -9.38001  10.13168  -22.69481 1.000 45.73185  ? 117 CYS A SG   1 
ATOM   1808 H H    . CYS A 1 117 ? -7.64850  6.85980   -22.31709 1.000 41.84682  ? 117 CYS A H    1 
ATOM   1809 H HA   . CYS A 1 117 ? -7.42619  8.68311   -24.30680 1.000 49.23458  ? 117 CYS A HA   1 
ATOM   1810 H HB2  . CYS A 1 117 ? -7.54318  9.35578   -21.55155 1.000 47.90863  ? 117 CYS A HB2  1 
ATOM   1811 H HB3  . CYS A 1 117 ? -7.09652  10.39256  -22.67004 1.000 47.90863  ? 117 CYS A HB3  1 
ATOM   1812 H HG   . CYS A 1 117 ? -10.09818 9.25596   -22.29813 1.000 54.87199  ? 117 CYS A HG   1 
ATOM   1813 N N    . TYR A 1 118 ? -4.98863  9.06661   -24.06165 1.000 45.13476  ? 118 TYR A N    1 
ATOM   1814 C CA   . TYR A 1 118 ? -3.53356  9.12771   -24.00171 1.000 43.27573  ? 118 TYR A CA   1 
ATOM   1815 C C    . TYR A 1 118 ? -3.11400  10.56566  -24.25849 1.000 48.25226  ? 118 TYR A C    1 
ATOM   1816 O O    . TYR A 1 118 ? -3.59184  11.19316  -25.20971 1.000 43.37239  ? 118 TYR A O    1 
ATOM   1817 C CB   . TYR A 1 118 ? -2.88505  8.18072   -25.01947 1.000 35.07902  ? 118 TYR A CB   1 
ATOM   1818 C CG   . TYR A 1 118 ? -3.27456  6.73789   -24.80730 1.000 42.89270  ? 118 TYR A CG   1 
ATOM   1819 C CD1  . TYR A 1 118 ? -2.54812  5.92231   -23.95249 1.000 36.30195  ? 118 TYR A CD1  1 
ATOM   1820 C CD2  . TYR A 1 118 ? -4.38516  6.19676   -25.44491 1.000 47.34729  ? 118 TYR A CD2  1 
ATOM   1821 C CE1  . TYR A 1 118 ? -2.90467  4.60798   -23.74782 1.000 33.18117  ? 118 TYR A CE1  1 
ATOM   1822 C CE2  . TYR A 1 118 ? -4.75312  4.88022   -25.24162 1.000 38.93689  ? 118 TYR A CE2  1 
ATOM   1823 C CZ   . TYR A 1 118 ? -4.00726  4.09038   -24.38860 1.000 41.77592  ? 118 TYR A CZ   1 
ATOM   1824 O OH   . TYR A 1 118 ? -4.35628  2.77545   -24.17011 1.000 41.11243  ? 118 TYR A OH   1 
ATOM   1825 H H    . TYR A 1 118 ? -5.32624  9.59696   -24.64847 1.000 54.15548  ? 118 TYR A H    1 
ATOM   1826 H HA   . TYR A 1 118 ? -3.22275  8.86230   -23.12202 1.000 51.92464  ? 118 TYR A HA   1 
ATOM   1827 H HB2  . TYR A 1 118 ? -3.16335  8.43852   -25.91221 1.000 42.08859  ? 118 TYR A HB2  1 
ATOM   1828 H HB3  . TYR A 1 118 ? -1.92043  8.24581   -24.94091 1.000 42.08859  ? 118 TYR A HB3  1 
ATOM   1829 H HD1  . TYR A 1 118 ? -1.80736  6.26905   -23.50983 1.000 43.55611  ? 118 TYR A HD1  1 
ATOM   1830 H HD2  . TYR A 1 118 ? -4.88861  6.72930   -26.01748 1.000 56.81052  ? 118 TYR A HD2  1 
ATOM   1831 H HE1  . TYR A 1 118 ? -2.40184  4.07167   -23.17823 1.000 39.81117  ? 118 TYR A HE1  1 
ATOM   1832 H HE2  . TYR A 1 118 ? -5.49686  4.52897   -25.67563 1.000 46.71804  ? 118 TYR A HE2  1 
ATOM   1833 H HH   . TYR A 1 118 ? -5.16047  2.65304   -24.37963 1.000 49.32869  ? 118 TYR A HH   1 
ATOM   1834 N N    . ASN A 1 119 ? -2.23608  11.08635  -23.39988 1.000 50.34190  ? 119 ASN A N    1 
ATOM   1835 C CA   . ASN A 1 119 ? -1.77881  12.47249  -23.48873 1.000 44.83858  ? 119 ASN A CA   1 
ATOM   1836 C C    . ASN A 1 119 ? -2.96018  13.43706  -23.54183 1.000 41.25907  ? 119 ASN A C    1 
ATOM   1837 O O    . ASN A 1 119 ? -2.94509  14.43539  -24.26484 1.000 46.54875  ? 119 ASN A O    1 
ATOM   1838 C CB   . ASN A 1 119 ? -0.86343  12.66932  -24.69755 1.000 44.91499  ? 119 ASN A CB   1 
ATOM   1839 C CG   . ASN A 1 119 ? 0.33893   11.74985  -24.67119 1.000 57.21541  ? 119 ASN A CG   1 
ATOM   1840 O OD1  . ASN A 1 119 ? 0.57002   10.98403  -25.60792 1.000 64.65000  ? 119 ASN A OD1  1 
ATOM   1841 N ND2  . ASN A 1 119 ? 1.11049   11.81559  -23.59142 1.000 57.80414  ? 119 ASN A ND2  1 
ATOM   1842 H H    . ASN A 1 119 ? -1.88556  10.64967  -22.74715 1.000 60.40406  ? 119 ASN A H    1 
ATOM   1843 H HA   . ASN A 1 119 ? -1.26889  12.67690  -22.68929 1.000 53.80007  ? 119 ASN A HA   1 
ATOM   1844 H HB2  . ASN A 1 119 ? -1.36451  12.48612  -25.50765 1.000 53.89176  ? 119 ASN A HB2  1 
ATOM   1845 H HB3  . ASN A 1 119 ? -0.54211  13.58452  -24.70603 1.000 53.89176  ? 119 ASN A HB3  1 
ATOM   1846 H HD21 . ASN A 1 119 ? 1.80574   11.31333  -23.52849 1.000 69.35874  ? 119 ASN A HD21 1 
ATOM   1847 H HD22 . ASN A 1 119 ? 0.91461   12.36039  -22.95548 1.000 69.35874  ? 119 ASN A HD22 1 
ATOM   1848 N N    . GLY A 1 120 ? -3.99814  13.13197  -22.76551 1.000 39.87919  ? 120 GLY A N    1 
ATOM   1849 C CA   . GLY A 1 120 ? -5.17065  13.97552  -22.68627 1.000 41.41579  ? 120 GLY A CA   1 
ATOM   1850 C C    . GLY A 1 120 ? -6.08097  13.95535  -23.89450 1.000 45.97043  ? 120 GLY A C    1 
ATOM   1851 O O    . GLY A 1 120 ? -7.07409  14.69167  -23.90351 1.000 40.80052  ? 120 GLY A O    1 
ATOM   1852 H H    . GLY A 1 120 ? -4.04122  12.43003  -22.27052 1.000 47.84880  ? 120 GLY A H    1 
ATOM   1853 H HA2  . GLY A 1 120 ? -5.69681  13.69787  -21.92013 1.000 49.69272  ? 120 GLY A HA2  1 
ATOM   1854 H HA3  . GLY A 1 120 ? -4.88073  14.89182  -22.55493 1.000 49.69272  ? 120 GLY A HA3  1 
ATOM   1855 N N    . SER A 1 121 ? -5.78715  13.14247  -24.91415 1.000 45.59037  ? 121 SER A N    1 
ATOM   1856 C CA   . SER A 1 121 ? -6.63358  13.06535  -26.09965 1.000 42.15696  ? 121 SER A CA   1 
ATOM   1857 C C    . SER A 1 121 ? -7.45032  11.78418  -26.06477 1.000 45.83485  ? 121 SER A C    1 
ATOM   1858 O O    . SER A 1 121 ? -6.86622  10.69531  -25.95208 1.000 35.09186  ? 121 SER A O    1 
ATOM   1859 C CB   . SER A 1 121 ? -5.78631  13.11200  -27.36663 1.000 35.05002  ? 121 SER A CB   1 
ATOM   1860 O OG   . SER A 1 121 ? -4.83557  14.15748  -27.29111 1.000 52.51236  ? 121 SER A OG   1 
ATOM   1861 H H    . SER A 1 121 ? -5.10025  12.62564  -24.93969 1.000 54.70222  ? 121 SER A H    1 
ATOM   1862 H HA   . SER A 1 121 ? -7.24365  13.81945  -26.10608 1.000 50.58213  ? 121 SER A HA   1 
ATOM   1863 H HB2  . SER A 1 121 ? -5.32071  12.26707  -27.46766 1.000 42.05380  ? 121 SER A HB2  1 
ATOM   1864 H HB3  . SER A 1 121 ? -6.36546  13.26495  -28.12958 1.000 42.05380  ? 121 SER A HB3  1 
ATOM   1865 H HG   . SER A 1 121 ? -4.32226  14.12754  -27.95536 1.000 63.00860  ? 121 SER A HG   1 
ATOM   1866 N N    . PRO A 1 122 ? -8.77976  11.85307  -26.12192 1.000 48.39721  ? 122 PRO A N    1 
ATOM   1867 C CA   . PRO A 1 122 ? -9.57506  10.62427  -26.25696 1.000 45.60681  ? 122 PRO A CA   1 
ATOM   1868 C C    . PRO A 1 122 ? -9.16640  9.80146   -27.47307 1.000 42.45645  ? 122 PRO A C    1 
ATOM   1869 O O    . PRO A 1 122 ? -9.04387  10.31953  -28.58405 1.000 48.94478  ? 122 PRO A O    1 
ATOM   1870 C CB   . PRO A 1 122 ? -11.00756 11.15221  -26.38794 1.000 44.94663  ? 122 PRO A CB   1 
ATOM   1871 C CG   . PRO A 1 122 ? -11.00226 12.43223  -25.60205 1.000 41.59884  ? 122 PRO A CG   1 
ATOM   1872 C CD   . PRO A 1 122 ? -9.60719  13.00520  -25.71076 1.000 40.83181  ? 122 PRO A CD   1 
ATOM   1873 H HA   . PRO A 1 122 ? -9.48605  10.07795  -25.46040 1.000 54.72195  ? 122 PRO A HA   1 
ATOM   1874 H HB2  . PRO A 1 122 ? -11.21882 11.31500  -27.32055 1.000 53.92973  ? 122 PRO A HB2  1 
ATOM   1875 H HB3  . PRO A 1 122 ? -11.63376 10.51361  -26.01249 1.000 53.92973  ? 122 PRO A HB3  1 
ATOM   1876 H HG2  . PRO A 1 122 ? -11.65228 13.04575  -25.97885 1.000 49.91238  ? 122 PRO A HG2  1 
ATOM   1877 H HG3  . PRO A 1 122 ? -11.22152 12.24411  -24.67607 1.000 49.91238  ? 122 PRO A HG3  1 
ATOM   1878 H HD2  . PRO A 1 122 ? -9.57582  13.70603  -26.38065 1.000 48.99195  ? 122 PRO A HD2  1 
ATOM   1879 H HD3  . PRO A 1 122 ? -9.31122  13.35138  -24.85434 1.000 48.99195  ? 122 PRO A HD3  1 
ATOM   1880 N N    . SER A 1 123 ? -8.97217  8.50214   -27.25195 1.000 42.73301  ? 123 SER A N    1 
ATOM   1881 C CA   . SER A 1 123 ? -8.59143  7.56395   -28.30387 1.000 42.50826  ? 123 SER A CA   1 
ATOM   1882 C C    . SER A 1 123 ? -9.73033  6.66299   -28.75638 1.000 41.40978  ? 123 SER A C    1 
ATOM   1883 O O    . SER A 1 123 ? -9.83349  6.36380   -29.94749 1.000 42.24983  ? 123 SER A O    1 
ATOM   1884 C CB   . SER A 1 123 ? -7.42241  6.69048   -27.83012 1.000 46.37096  ? 123 SER A CB   1 
ATOM   1885 O OG   . SER A 1 123 ? -7.16765  5.63490   -28.74279 1.000 64.94414  ? 123 SER A OG   1 
ATOM   1886 H H    . SER A 1 123 ? -9.05748  8.13197   -26.48040 1.000 51.27338  ? 123 SER A H    1 
ATOM   1887 H HA   . SER A 1 123 ? -8.29428  8.07067   -29.07577 1.000 51.00369  ? 123 SER A HA   1 
ATOM   1888 H HB2  . SER A 1 123 ? -6.62757  7.24170   -27.75732 1.000 55.63892  ? 123 SER A HB2  1 
ATOM   1889 H HB3  . SER A 1 123 ? -7.64367  6.31148   -26.96508 1.000 55.63892  ? 123 SER A HB3  1 
ATOM   1890 H HG   . SER A 1 123 ? -6.56809  5.13099   -28.43914 1.000 77.92674  ? 123 SER A HG   1 
ATOM   1891 N N    . GLY A 1 124 ? -10.58565 6.21752   -27.84148 1.000 36.05852  ? 124 GLY A N    1 
ATOM   1892 C CA   . GLY A 1 124 ? -11.69711 5.35456   -28.20531 1.000 36.30159  ? 124 GLY A CA   1 
ATOM   1893 C C    . GLY A 1 124 ? -12.60438 5.13085   -27.01679 1.000 36.63138  ? 124 GLY A C    1 
ATOM   1894 O O    . GLY A 1 124 ? -12.26920 5.46730   -25.87771 1.000 38.82261  ? 124 GLY A O    1 
ATOM   1895 H H    . GLY A 1 124 ? -10.54239 6.40201   -27.00262 1.000 43.26399  ? 124 GLY A H    1 
ATOM   1896 H HA2  . GLY A 1 124 ? -12.21111 5.76346   -28.91911 1.000 43.55568  ? 124 GLY A HA2  1 
ATOM   1897 H HA3  . GLY A 1 124 ? -11.36170 4.49661   -28.50916 1.000 43.55568  ? 124 GLY A HA3  1 
ATOM   1898 N N    . VAL A 1 125 ? -13.77087 4.55437   -27.29740 1.000 28.15183  ? 125 VAL A N    1 
ATOM   1899 C CA   . VAL A 1 125 ? -14.78121 4.31020   -26.27537 1.000 32.94343  ? 125 VAL A CA   1 
ATOM   1900 C C    . VAL A 1 125 ? -15.27361 2.87380   -26.38905 1.000 36.28191  ? 125 VAL A C    1 
ATOM   1901 O O    . VAL A 1 125 ? -15.45060 2.34829   -27.49410 1.000 31.53454  ? 125 VAL A O    1 
ATOM   1902 C CB   . VAL A 1 125 ? -15.95303 5.31193   -26.38829 1.000 32.68335  ? 125 VAL A CB   1 
ATOM   1903 C CG1  . VAL A 1 125 ? -16.55363 5.29020   -27.78069 1.000 38.79609  ? 125 VAL A CG1  1 
ATOM   1904 C CG2  . VAL A 1 125 ? -17.01076 5.01698   -25.34314 1.000 33.07881  ? 125 VAL A CG2  1 
ATOM   1905 H H    . VAL A 1 125 ? -14.00124 4.29311   -28.08370 1.000 33.77597  ? 125 VAL A H    1 
ATOM   1906 H HA   . VAL A 1 125 ? -14.37775 4.41084   -25.39902 1.000 39.52588  ? 125 VAL A HA   1 
ATOM   1907 H HB   . VAL A 1 125 ? -15.61037 6.20501   -26.22744 1.000 39.21379  ? 125 VAL A HB   1 
ATOM   1908 H HG11 . VAL A 1 125 ? -17.29637 5.91320   -27.81400 1.000 46.54908  ? 125 VAL A HG11 1 
ATOM   1909 H HG12 . VAL A 1 125 ? -15.87408 5.55107   -28.42184 1.000 46.54908  ? 125 VAL A HG12 1 
ATOM   1910 H HG13 . VAL A 1 125 ? -16.86562 4.39277   -27.97608 1.000 46.54908  ? 125 VAL A HG13 1 
ATOM   1911 H HG21 . VAL A 1 125 ? -16.59580 4.56243   -24.59341 1.000 39.68835  ? 125 VAL A HG21 1 
ATOM   1912 H HG22 . VAL A 1 125 ? -17.40369 5.85287   -25.04685 1.000 39.68835  ? 125 VAL A HG22 1 
ATOM   1913 H HG23 . VAL A 1 125 ? -17.69382 4.45130   -25.73600 1.000 39.68835  ? 125 VAL A HG23 1 
ATOM   1914 N N    . TYR A 1 126 ? -15.47264 2.23309   -25.23936 1.000 29.35052  ? 126 TYR A N    1 
ATOM   1915 C CA   . TYR A 1 126 ? -16.02631 0.88915   -25.19766 1.000 33.43949  ? 126 TYR A CA   1 
ATOM   1916 C C    . TYR A 1 126 ? -16.77488 0.70343   -23.88359 1.000 30.05003  ? 126 TYR A C    1 
ATOM   1917 O O    . TYR A 1 126 ? -16.67100 1.51624   -22.96198 1.000 29.27286  ? 126 TYR A O    1 
ATOM   1918 C CB   . TYR A 1 126 ? -14.93028 -0.16425  -25.38301 1.000 33.35922  ? 126 TYR A CB   1 
ATOM   1919 C CG   . TYR A 1 126 ? -13.76201 -0.03551  -24.43428 1.000 30.50383  ? 126 TYR A CG   1 
ATOM   1920 C CD1  . TYR A 1 126 ? -13.81604 -0.59105  -23.17064 1.000 29.76313  ? 126 TYR A CD1  1 
ATOM   1921 C CD2  . TYR A 1 126 ? -12.59979 0.62433   -24.80995 1.000 35.44172  ? 126 TYR A CD2  1 
ATOM   1922 C CE1  . TYR A 1 126 ? -12.75610 -0.48997  -22.29932 1.000 33.83697  ? 126 TYR A CE1  1 
ATOM   1923 C CE2  . TYR A 1 126 ? -11.52825 0.73033   -23.94332 1.000 32.08989  ? 126 TYR A CE2  1 
ATOM   1924 C CZ   . TYR A 1 126 ? -11.61437 0.16891   -22.68881 1.000 38.85042  ? 126 TYR A CZ   1 
ATOM   1925 O OH   . TYR A 1 126 ? -10.55765 0.26548   -21.81566 1.000 42.50811  ? 126 TYR A OH   1 
ATOM   1926 H H    . TYR A 1 126 ? -15.29247 2.56098   -24.46500 1.000 35.21439  ? 126 TYR A H    1 
ATOM   1927 H HA   . TYR A 1 126 ? -16.66934 0.77911   -25.91551 1.000 40.12116  ? 126 TYR A HA   1 
ATOM   1928 H HB2  . TYR A 1 126 ? -15.32064 -1.04187  -25.24775 1.000 40.02484  ? 126 TYR A HB2  1 
ATOM   1929 H HB3  . TYR A 1 126 ? -14.58257 -0.09133  -26.28560 1.000 40.02484  ? 126 TYR A HB3  1 
ATOM   1930 H HD1  . TYR A 1 126 ? -14.58412 -1.04232  -22.90361 1.000 35.70953  ? 126 TYR A HD1  1 
ATOM   1931 H HD2  . TYR A 1 126 ? -12.54126 1.00102   -25.65823 1.000 42.52384  ? 126 TYR A HD2  1 
ATOM   1932 H HE1  . TYR A 1 126 ? -12.81187 -0.86581  -21.45048 1.000 40.59813  ? 126 TYR A HE1  1 
ATOM   1933 H HE2  . TYR A 1 126 ? -10.75571 1.17699   -24.20520 1.000 38.50164  ? 126 TYR A HE2  1 
ATOM   1934 H HH   . TYR A 1 126 ? -9.90844  0.64389   -22.19106 1.000 51.00351  ? 126 TYR A HH   1 
ATOM   1935 N N    . GLN A 1 127 ? -17.54620 -0.37894  -23.81644 1.000 37.09633  ? 127 GLN A N    1 
ATOM   1936 C CA   . GLN A 1 127 ? -18.41279 -0.68676  -22.68607 1.000 35.70708  ? 127 GLN A CA   1 
ATOM   1937 C C    . GLN A 1 127 ? -17.83619 -1.85933  -21.90417 1.000 34.95525  ? 127 GLN A C    1 
ATOM   1938 O O    . GLN A 1 127 ? -17.35897 -2.83330  -22.49432 1.000 41.60383  ? 127 GLN A O    1 
ATOM   1939 C CB   . GLN A 1 127 ? -19.82360 -1.02436  -23.17783 1.000 35.18565  ? 127 GLN A CB   1 
ATOM   1940 C CG   . GLN A 1 127 ? -20.87160 -1.13088  -22.09960 1.000 36.24536  ? 127 GLN A CG   1 
ATOM   1941 C CD   . GLN A 1 127 ? -21.39311 0.22017   -21.66689 1.000 37.67234  ? 127 GLN A CD   1 
ATOM   1942 O OE1  . GLN A 1 127 ? -20.87447 1.25948   -22.07453 1.000 40.47568  ? 127 GLN A OE1  1 
ATOM   1943 N NE2  . GLN A 1 127 ? -22.42939 0.21425   -20.83906 1.000 40.80897  ? 127 GLN A NE2  1 
ATOM   1944 H H    . GLN A 1 127 ? -17.58476 -0.97153  -24.43849 1.000 44.50936  ? 127 GLN A H    1 
ATOM   1945 H HA   . GLN A 1 127 ? -18.46806 0.07482   -22.08786 1.000 42.84227  ? 127 GLN A HA   1 
ATOM   1946 H HB2  . GLN A 1 127 ? -20.10848 -0.32901  -23.79121 1.000 42.21656  ? 127 GLN A HB2  1 
ATOM   1947 H HB3  . GLN A 1 127 ? -19.79166 -1.87854  -23.63636 1.000 42.21656  ? 127 GLN A HB3  1 
ATOM   1948 H HG2  . GLN A 1 127 ? -21.61979 -1.64958  -22.43436 1.000 43.48820  ? 127 GLN A HG2  1 
ATOM   1949 H HG3  . GLN A 1 127 ? -20.48581 -1.56747  -21.32406 1.000 43.48820  ? 127 GLN A HG3  1 
ATOM   1950 H HE21 . GLN A 1 127 ? -22.76708 -0.53241  -20.57817 1.000 48.96454  ? 127 GLN A HE21 1 
ATOM   1951 H HE22 . GLN A 1 127 ? -22.76363 0.95707   -20.56320 1.000 48.96454  ? 127 GLN A HE22 1 
ATOM   1952 N N    A CYS A 1 128 ? -17.88887 -1.78408  -20.57952 0.500 36.98612  ? 128 CYS A N    1 
ATOM   1953 N N    B CYS A 1 128 ? -17.88208 -1.74427  -20.57277 0.500 38.72865  ? 128 CYS A N    1 
ATOM   1954 C CA   A CYS A 1 128 ? -17.39227 -2.88037  -19.76305 0.500 38.68557  ? 128 CYS A CA   1 
ATOM   1955 C CA   B CYS A 1 128 ? -17.30292 -2.70441  -19.64296 0.500 38.63146  ? 128 CYS A CA   1 
ATOM   1956 C C    A CYS A 1 128 ? -18.23808 -2.98759  -18.50312 0.500 37.89552  ? 128 CYS A C    1 
ATOM   1957 C C    B CYS A 1 128 ? -18.31202 -3.05361  -18.55540 0.500 37.93043  ? 128 CYS A C    1 
ATOM   1958 O O    A CYS A 1 128 ? -19.14879 -2.18897  -18.26710 0.500 38.38187  ? 128 CYS A O    1 
ATOM   1959 O O    B CYS A 1 128 ? -19.41581 -2.50203  -18.49458 0.500 38.98835  ? 128 CYS A O    1 
ATOM   1960 C CB   A CYS A 1 128 ? -15.91243 -2.68985  -19.42041 0.500 38.15772  ? 128 CYS A CB   1 
ATOM   1961 C CB   B CYS A 1 128 ? -16.03483 -2.15024  -18.98090 0.500 37.38072  ? 128 CYS A CB   1 
ATOM   1962 S SG   A CYS A 1 128 ? -15.58578 -1.27724  -18.35479 0.500 40.99780  ? 128 CYS A SG   1 
ATOM   1963 S SG   B CYS A 1 128 ? -14.57813 -2.11700  -20.02126 0.500 43.12886  ? 128 CYS A SG   1 
ATOM   1964 H H    A CYS A 1 128 ? -18.20373 -1.11692  -20.13754 0.500 44.37712  ? 128 CYS A H    1 
ATOM   1965 H H    B CYS A 1 128 ? -18.26239 -1.08572  -20.17118 0.500 46.46815  ? 128 CYS A H    1 
ATOM   1966 H HA   A CYS A 1 128 ? -17.49070 -3.70404  -20.26581 0.500 46.41646  ? 128 CYS A HA   1 
ATOM   1967 H HA   B CYS A 1 128 ? -17.08762 -3.50466  -20.14708 0.500 46.35152  ? 128 CYS A HA   1 
ATOM   1968 H HB2  A CYS A 1 128 ? -15.59414 -3.48426  -18.96380 0.500 45.78303  ? 128 CYS A HB2  1 
ATOM   1969 H HB2  B CYS A 1 128 ? -16.21048 -1.23863  -18.69981 0.500 44.85064  ? 128 CYS A HB2  1 
ATOM   1970 H HB3  A CYS A 1 128 ? -15.41679 -2.55955  -20.24398 0.500 45.78303  ? 128 CYS A HB3  1 
ATOM   1971 H HB3  B CYS A 1 128 ? -15.82720 -2.70098  -18.20988 0.500 44.85064  ? 128 CYS A HB3  1 
ATOM   1972 H HG   A CYS A 1 128 ? -15.94900 -0.27709  -18.90957 0.500 49.19113  ? 128 CYS A HG   1 
ATOM   1973 H HG   B CYS A 1 128 ? -14.80034 -1.43447  -20.98292 0.500 51.74840  ? 128 CYS A HG   1 
ATOM   1974 N N    . ALA A 1 129 ? -17.91994 -3.99030  -17.69187 1.000 38.92783  ? 129 ALA A N    1 
ATOM   1975 C CA   . ALA A 1 129 ? -18.63635 -4.28490  -16.46371 1.000 34.61111  ? 129 ALA A CA   1 
ATOM   1976 C C    . ALA A 1 129 ? -17.63762 -4.39920  -15.32415 1.000 35.78838  ? 129 ALA A C    1 
ATOM   1977 O O    . ALA A 1 129 ? -16.51605 -4.88036  -15.51439 1.000 35.48036  ? 129 ALA A O    1 
ATOM   1978 C CB   . ALA A 1 129 ? -19.43760 -5.58573  -16.59182 1.000 35.80981  ? 129 ALA A CB   1 
ATOM   1979 H H    . ALA A 1 129 ? -17.26908 -4.53320  -17.83758 1.000 46.70716  ? 129 ALA A H    1 
ATOM   1980 H HA   . ALA A 1 129 ? -19.25575 -3.56708  -16.25884 1.000 41.52710  ? 129 ALA A HA   1 
ATOM   1981 H HB1  . ALA A 1 129 ? -19.98112 -5.54413  -17.39416 1.000 42.96554  ? 129 ALA A HB1  1 
ATOM   1982 H HB2  . ALA A 1 129 ? -18.82084 -6.33226  -16.64843 1.000 42.96554  ? 129 ALA A HB2  1 
ATOM   1983 H HB3  . ALA A 1 129 ? -20.00597 -5.68464  -15.81203 1.000 42.96554  ? 129 ALA A HB3  1 
ATOM   1984 N N    . MET A 1 130 ? -18.03677 -3.92841  -14.14816 1.000 40.02125  ? 130 MET A N    1 
ATOM   1985 C CA   . MET A 1 130 ? -17.29518 -4.22274  -12.92881 1.000 38.97244  ? 130 MET A CA   1 
ATOM   1986 C C    . MET A 1 130 ? -17.47175 -5.70403  -12.61398 1.000 36.72455  ? 130 MET A C    1 
ATOM   1987 O O    . MET A 1 130 ? -18.57893 -6.15129  -12.29741 1.000 38.39338  ? 130 MET A O    1 
ATOM   1988 C CB   . MET A 1 130 ? -17.79099 -3.34563  -11.78405 1.000 36.21655  ? 130 MET A CB   1 
ATOM   1989 C CG   . MET A 1 130 ? -17.05603 -3.55680  -10.46956 1.000 41.70563  ? 130 MET A CG   1 
ATOM   1990 S SD   . MET A 1 130 ? -15.29939 -3.15912  -10.56959 1.000 34.74070  ? 130 MET A SD   1 
ATOM   1991 C CE   . MET A 1 130 ? -15.35290 -1.39975  -10.87300 1.000 28.14773  ? 130 MET A CE   1 
ATOM   1992 H H    . MET A 1 130 ? -18.73266 -3.43705  -14.03031 1.000 48.01927  ? 130 MET A H    1 
ATOM   1993 H HA   . MET A 1 130 ? -16.35462 -4.02223  -13.05544 1.000 46.76070  ? 130 MET A HA   1 
ATOM   1994 H HB2  . MET A 1 130 ? -17.68036 -2.41556  -12.03631 1.000 43.45363  ? 130 MET A HB2  1 
ATOM   1995 H HB3  . MET A 1 130 ? -18.72914 -3.53834  -11.63028 1.000 43.45363  ? 130 MET A HB3  1 
ATOM   1996 H HG2  . MET A 1 130 ? -17.45295 -2.98741  -9.79196  1.000 50.04052  ? 130 MET A HG2  1 
ATOM   1997 H HG3  . MET A 1 130 ? -17.13706 -4.48780  -10.20962 1.000 50.04052  ? 130 MET A HG3  1 
ATOM   1998 H HE1  . MET A 1 130 ? -14.45095 -1.04498  -10.83399 1.000 33.77104  ? 130 MET A HE1  1 
ATOM   1999 H HE2  . MET A 1 130 ? -15.73260 -1.24220  -11.75159 1.000 33.77104  ? 130 MET A HE2  1 
ATOM   2000 H HE3  . MET A 1 130 ? -15.90354 -0.97885  -10.19437 1.000 33.77104  ? 130 MET A HE3  1 
ATOM   2001 N N    . ARG A 1 131 ? -16.39238 -6.47342  -12.72420 1.000 32.22661  ? 131 ARG A N    1 
ATOM   2002 C CA   . ARG A 1 131 ? -16.47336 -7.90061  -12.47506 1.000 37.99797  ? 131 ARG A CA   1 
ATOM   2003 C C    . ARG A 1 131 ? -16.69550 -8.16359  -10.98504 1.000 39.57836  ? 131 ARG A C    1 
ATOM   2004 O O    . ARG A 1 131 ? -16.38730 -7.31927  -10.13980 1.000 36.05950  ? 131 ARG A O    1 
ATOM   2005 C CB   . ARG A 1 131 ? -15.20326 -8.60228  -12.95435 1.000 39.61118  ? 131 ARG A CB   1 
ATOM   2006 C CG   . ARG A 1 131 ? -14.84577 -8.36939  -14.42988 1.000 38.11016  ? 131 ARG A CG   1 
ATOM   2007 C CD   . ARG A 1 131 ? -15.96058 -8.77497  -15.38002 1.000 37.14859  ? 131 ARG A CD   1 
ATOM   2008 N NE   . ARG A 1 131 ? -16.54028 -10.07002 -15.04667 1.000 37.28519  ? 131 ARG A NE   1 
ATOM   2009 C CZ   . ARG A 1 131 ? -17.54915 -10.62714 -15.70216 1.000 36.86167  ? 131 ARG A CZ   1 
ATOM   2010 N NH1  . ARG A 1 131 ? -18.08984 -10.04585 -16.76121 1.000 42.15329  ? 131 ARG A NH1  1 
ATOM   2011 N NH2  . ARG A 1 131 ? -18.03086 -11.79378 -15.28169 1.000 35.09075  ? 131 ARG A NH2  1 
ATOM   2012 H H    . ARG A 1 131 ? -15.60905 -6.19192  -12.94043 1.000 38.66571  ? 131 ARG A H    1 
ATOM   2013 H HA   . ARG A 1 131 ? -17.22132 -8.27543  -12.96595 1.000 45.59134  ? 131 ARG A HA   1 
ATOM   2014 H HB2  . ARG A 1 131 ? -14.45780 -8.28407  -12.42149 1.000 47.52719  ? 131 ARG A HB2  1 
ATOM   2015 H HB3  . ARG A 1 131 ? -15.31573 -9.55772  -12.83037 1.000 47.52719  ? 131 ARG A HB3  1 
ATOM   2016 H HG2  . ARG A 1 131 ? -14.66538 -7.42610  -14.56613 1.000 45.72597  ? 131 ARG A HG2  1 
ATOM   2017 H HG3  . ARG A 1 131 ? -14.05957 -8.89281  -14.65084 1.000 45.72597  ? 131 ARG A HG3  1 
ATOM   2018 H HD2  . ARG A 1 131 ? -16.66681 -8.11118  -15.34105 1.000 44.57207  ? 131 ARG A HD2  1 
ATOM   2019 H HD3  . ARG A 1 131 ? -15.60488 -8.82844  -16.28086 1.000 44.57207  ? 131 ARG A HD3  1 
ATOM   2020 H HE   . ARG A 1 131 ? -16.20619 -10.50082 -14.38154 1.000 44.73600  ? 131 ARG A HE   1 
ATOM   2021 H HH11 . ARG A 1 131 ? -17.78726 -9.29000  -17.03823 1.000 50.57771  ? 131 ARG A HH11 1 
ATOM   2022 H HH12 . ARG A 1 131 ? -18.74373 -10.42401 -17.17233 1.000 50.57771  ? 131 ARG A HH12 1 
ATOM   2023 H HH21 . ARG A 1 131 ? -17.68804 -12.17728 -14.59249 1.000 42.10267  ? 131 ARG A HH21 1 
ATOM   2024 H HH22 . ARG A 1 131 ? -18.68506 -12.16444 -15.69909 1.000 42.10267  ? 131 ARG A HH22 1 
ATOM   2025 N N    . PRO A 1 132 ? -17.26413 -9.32285  -10.64119 1.000 40.82935  ? 132 PRO A N    1 
ATOM   2026 C CA   . PRO A 1 132 ? -17.43445 -9.65649  -9.21642  1.000 47.90029  ? 132 PRO A CA   1 
ATOM   2027 C C    . PRO A 1 132 ? -16.13916 -9.66444  -8.42295  1.000 37.41102  ? 132 PRO A C    1 
ATOM   2028 O O    . PRO A 1 132 ? -16.17618 -9.45588  -7.20436  1.000 45.21391  ? 132 PRO A O    1 
ATOM   2029 C CB   . PRO A 1 132 ? -18.08023 -11.04819 -9.26516  1.000 42.03323  ? 132 PRO A CB   1 
ATOM   2030 C CG   . PRO A 1 132 ? -18.85567 -11.03769 -10.53967 1.000 40.07060  ? 132 PRO A CG   1 
ATOM   2031 C CD   . PRO A 1 132 ? -18.02772 -10.23317 -11.51411 1.000 37.57437  ? 132 PRO A CD   1 
ATOM   2032 H HA   . PRO A 1 132 ? -18.04710 -9.02721  -8.80466  1.000 57.47412  ? 132 PRO A HA   1 
ATOM   2033 H HB2  . PRO A 1 132 ? -17.39525 -11.73490 -9.27634  1.000 50.43364  ? 132 PRO A HB2  1 
ATOM   2034 H HB3  . PRO A 1 132 ? -18.66333 -11.17365 -8.50020  1.000 50.43364  ? 132 PRO A HB3  1 
ATOM   2035 H HG2  . PRO A 1 132 ? -18.97574 -11.94608 -10.85797 1.000 48.07850  ? 132 PRO A HG2  1 
ATOM   2036 H HG3  . PRO A 1 132 ? -19.71909 -10.62007 -10.39478 1.000 48.07850  ? 132 PRO A HG3  1 
ATOM   2037 H HD2  . PRO A 1 132 ? -17.43151 -10.80902 -12.01792 1.000 45.08302  ? 132 PRO A HD2  1 
ATOM   2038 H HD3  . PRO A 1 132 ? -18.59691 -9.73347  -12.12011 1.000 45.08302  ? 132 PRO A HD3  1 
ATOM   2039 N N    . ASN A 1 133 ? -14.99623 -9.90190  -9.06032  1.000 33.75228  ? 133 ASN A N    1 
ATOM   2040 C CA   . ASN A 1 133 ? -13.71465 -9.80915  -8.37539  1.000 37.66050  ? 133 ASN A CA   1 
ATOM   2041 C C    . ASN A 1 133 ? -13.12744 -8.40223  -8.42395  1.000 38.33337  ? 133 ASN A C    1 
ATOM   2042 O O    . ASN A 1 133 ? -11.94607 -8.22610  -8.11208  1.000 39.50173  ? 133 ASN A O    1 
ATOM   2043 C CB   . ASN A 1 133 ? -12.71852 -10.81543 -8.96226  1.000 38.32055  ? 133 ASN A CB   1 
ATOM   2044 C CG   . ASN A 1 133 ? -12.30110 -10.47931 -10.38588 1.000 40.69260  ? 133 ASN A CG   1 
ATOM   2045 O OD1  . ASN A 1 133 ? -12.64442 -9.42611  -10.92196 1.000 40.75015  ? 133 ASN A OD1  1 
ATOM   2046 N ND2  . ASN A 1 133 ? -11.54524 -11.37987 -11.00200 1.000 37.97285  ? 133 ASN A ND2  1 
ATOM   2047 H H    . ASN A 1 133 ? -14.93935 -10.11856 -9.89064  1.000 40.49651  ? 133 ASN A H    1 
ATOM   2048 H HA   . ASN A 1 133 ? -13.84727 -10.04442 -7.44374  1.000 45.18637  ? 133 ASN A HA   1 
ATOM   2049 H HB2  . ASN A 1 133 ? -11.92010 -10.82598 -8.41152  1.000 45.97843  ? 133 ASN A HB2  1 
ATOM   2050 H HB3  . ASN A 1 133 ? -13.12739 -11.69500 -8.97068  1.000 45.97843  ? 133 ASN A HB3  1 
ATOM   2051 H HD21 . ASN A 1 133 ? -11.28094 -11.24016 -11.80837 1.000 45.56120  ? 133 ASN A HD21 1 
ATOM   2052 H HD22 . ASN A 1 133 ? -11.31982 -12.10305 -10.59481 1.000 45.56120  ? 133 ASN A HD22 1 
ATOM   2053 N N    . PHE A 1 134 ? -13.91945 -7.40698  -8.82498  1.000 36.90147  ? 134 PHE A N    1 
ATOM   2054 C CA   . PHE A 1 134 ? -13.53193 -5.99934  -8.77280  1.000 39.91221  ? 134 PHE A CA   1 
ATOM   2055 C C    . PHE A 1 134 ? -12.42208 -5.65878  -9.76046  1.000 40.84048  ? 134 PHE A C    1 
ATOM   2056 O O    . PHE A 1 134 ? -11.66072 -4.71302  -9.54728  1.000 42.65937  ? 134 PHE A O    1 
ATOM   2057 C CB   . PHE A 1 134 ? -13.13013 -5.59581  -7.35110  1.000 40.99357  ? 134 PHE A CB   1 
ATOM   2058 C CG   . PHE A 1 134 ? -14.27784 -5.61197  -6.38454  1.000 41.85049  ? 134 PHE A CG   1 
ATOM   2059 C CD1  . PHE A 1 134 ? -15.16664 -4.55128  -6.33287  1.000 45.29833  ? 134 PHE A CD1  1 
ATOM   2060 C CD2  . PHE A 1 134 ? -14.48530 -6.69544  -5.54734  1.000 46.86638  ? 134 PHE A CD2  1 
ATOM   2061 C CE1  . PHE A 1 134 ? -16.23581 -4.56322  -5.45159  1.000 62.19490  ? 134 PHE A CE1  1 
ATOM   2062 C CE2  . PHE A 1 134 ? -15.55284 -6.71455  -4.66254  1.000 47.28927  ? 134 PHE A CE2  1 
ATOM   2063 C CZ   . PHE A 1 134 ? -16.42763 -5.64699  -4.61547  1.000 48.36990  ? 134 PHE A CZ   1 
ATOM   2064 H H    . PHE A 1 134 ? -14.71029 -7.52727  -9.14073  1.000 44.27553  ? 134 PHE A H    1 
ATOM   2065 H HA   . PHE A 1 134 ? -14.30056 -5.46746  -9.03207  1.000 47.88842  ? 134 PHE A HA   1 
ATOM   2066 H HB2  . PHE A 1 134 ? -12.45831 -6.21582  -7.02683  1.000 49.18606  ? 134 PHE A HB2  1 
ATOM   2067 H HB3  . PHE A 1 134 ? -12.76911 -4.69571  -7.37046  1.000 49.18606  ? 134 PHE A HB3  1 
ATOM   2068 H HD1  . PHE A 1 134 ? -15.04440 -3.82185  -6.89670  1.000 54.35176  ? 134 PHE A HD1  1 
ATOM   2069 H HD2  . PHE A 1 134 ? -13.90170 -7.41885  -5.57891  1.000 56.23342  ? 134 PHE A HD2  1 
ATOM   2070 H HE1  . PHE A 1 134 ? -16.82353 -3.84304  -5.42271  1.000 74.62765  ? 134 PHE A HE1  1 
ATOM   2071 H HE2  . PHE A 1 134 ? -15.67955 -7.44538  -4.10153  1.000 56.74089  ? 134 PHE A HE2  1 
ATOM   2072 H HZ   . PHE A 1 134 ? -17.14408 -5.65726  -4.02260  1.000 58.03766  ? 134 PHE A HZ   1 
ATOM   2073 N N    . THR A 1 135 ? -12.32528 -6.41021  -10.84812 1.000 37.38433  ? 135 THR A N    1 
ATOM   2074 C CA   . THR A 1 135 ? -11.51684 -6.02232  -11.99124 1.000 37.53342  ? 135 THR A CA   1 
ATOM   2075 C C    . THR A 1 135 ? -12.44004 -5.66034  -13.14490 1.000 40.30309  ? 135 THR A C    1 
ATOM   2076 O O    . THR A 1 135 ? -13.65546 -5.86607  -13.08792 1.000 36.32681  ? 135 THR A O    1 
ATOM   2077 C CB   . THR A 1 135 ? -10.55979 -7.14366  -12.41047 1.000 42.27048  ? 135 THR A CB   1 
ATOM   2078 O OG1  . THR A 1 135 ? -11.30576 -8.23849  -12.95586 1.000 37.37592  ? 135 THR A OG1  1 
ATOM   2079 C CG2  . THR A 1 135 ? -9.74757  -7.62585  -11.21867 1.000 41.33409  ? 135 THR A CG2  1 
ATOM   2080 H H    . THR A 1 135 ? -12.72732 -7.16388  -10.94788 1.000 44.85496  ? 135 THR A H    1 
ATOM   2081 H HA   . THR A 1 135 ? -10.97423 -5.25326  -11.75666 1.000 45.03387  ? 135 THR A HA   1 
ATOM   2082 H HB   . THR A 1 135 ? -9.94567  -6.80892  -13.08257 1.000 50.71834  ? 135 THR A HB   1 
ATOM   2083 H HG1  . THR A 1 135 ? -10.78172 -8.81596  -13.26811 1.000 44.84487  ? 135 THR A HG1  1 
ATOM   2084 H HG21 . THR A 1 135 ? -10.27046 -8.25005  -10.69154 1.000 49.59468  ? 135 THR A HG21 1 
ATOM   2085 H HG22 . THR A 1 135 ? -8.94143  -8.07026  -11.52454 1.000 49.59468  ? 135 THR A HG22 1 
ATOM   2086 H HG23 . THR A 1 135 ? -9.49923  -6.87283  -10.65993 1.000 49.59468  ? 135 THR A HG23 1 
ATOM   2087 N N    . ILE A 1 136 ? -11.85076 -5.10170  -14.19514 1.000 35.25873  ? 136 ILE A N    1 
ATOM   2088 C CA   . ILE A 1 136 ? -12.55708 -4.85858  -15.44409 1.000 39.05794  ? 136 ILE A CA   1 
ATOM   2089 C C    . ILE A 1 136 ? -11.69828 -5.41106  -16.57112 1.000 36.43114  ? 136 ILE A C    1 
ATOM   2090 O O    . ILE A 1 136 ? -10.46939 -5.27929  -16.54878 1.000 36.81567  ? 136 ILE A O    1 
ATOM   2091 C CB   . ILE A 1 136 ? -12.88276 -3.36226  -15.65722 1.000 40.92782  ? 136 ILE A CB   1 
ATOM   2092 C CG1  . ILE A 1 136 ? -11.61633 -2.51316  -15.79001 1.000 39.24974  ? 136 ILE A CG1  1 
ATOM   2093 C CG2  . ILE A 1 136 ? -13.74422 -2.83900  -14.50237 1.000 41.13814  ? 136 ILE A CG2  1 
ATOM   2094 C CD1  . ILE A 1 136 ? -11.88261 -1.12140  -16.33973 1.000 35.32525  ? 136 ILE A CD1  1 
ATOM   2095 H H    . ILE A 1 136 ? -11.02819 -4.85104  -14.20731 1.000 42.30425  ? 136 ILE A H    1 
ATOM   2096 H HA   . ILE A 1 136 ? -13.40464 -5.33030  -15.43890 1.000 46.86330  ? 136 ILE A HA   1 
ATOM   2097 H HB   . ILE A 1 136 ? -13.37426 -3.29097  -16.49043 1.000 49.10716  ? 136 ILE A HB   1 
ATOM   2098 H HG12 . ILE A 1 136 ? -11.21066 -2.41543  -14.91435 1.000 47.09346  ? 136 ILE A HG12 1 
ATOM   2099 H HG13 . ILE A 1 136 ? -11.00104 -2.95927  -16.39276 1.000 47.09346  ? 136 ILE A HG13 1 
ATOM   2100 H HG21 . ILE A 1 136 ? -13.35945 -3.13436  -13.66236 1.000 49.35953  ? 136 ILE A HG21 1 
ATOM   2101 H HG22 . ILE A 1 136 ? -13.76178 -1.86973  -14.53549 1.000 49.35953  ? 136 ILE A HG22 1 
ATOM   2102 H HG23 . ILE A 1 136 ? -14.64387 -3.18951  -14.59549 1.000 49.35953  ? 136 ILE A HG23 1 
ATOM   2103 H HD11 . ILE A 1 136 ? -12.38647 -0.61403  -15.68428 1.000 42.38407  ? 136 ILE A HD11 1 
ATOM   2104 H HD12 . ILE A 1 136 ? -11.03498 -0.68404  -16.51620 1.000 42.38407  ? 136 ILE A HD12 1 
ATOM   2105 H HD13 . ILE A 1 136 ? -12.39237 -1.19858  -17.16136 1.000 42.38407  ? 136 ILE A HD13 1 
ATOM   2106 N N    . LYS A 1 137 ? -12.34251 -6.06781  -17.53292 1.000 44.81269  ? 137 LYS A N    1 
ATOM   2107 C CA   . LYS A 1 137 ? -11.65564 -6.61537  -18.70220 1.000 41.69402  ? 137 LYS A CA   1 
ATOM   2108 C C    . LYS A 1 137 ? -11.63920 -5.51850  -19.75785 1.000 38.81490  ? 137 LYS A C    1 
ATOM   2109 O O    . LYS A 1 137 ? -12.53860 -5.41161  -20.59315 1.000 34.79541  ? 137 LYS A O    1 
ATOM   2110 C CB   . LYS A 1 137 ? -12.34584 -7.88284  -19.19171 1.000 49.28248  ? 137 LYS A CB   1 
ATOM   2111 C CG   . LYS A 1 137 ? -12.75090 -8.83668  -18.06301 1.000 56.95109  ? 137 LYS A CG   1 
ATOM   2112 C CD   . LYS A 1 137 ? -12.61535 -10.30988 -18.45889 1.000 65.15397  ? 137 LYS A CD   1 
ATOM   2113 C CE   . LYS A 1 137 ? -11.79649 -11.10344 -17.43608 1.000 71.66462  ? 137 LYS A CE   1 
ATOM   2114 N NZ   . LYS A 1 137 ? -12.58775 -11.52353 -16.23600 1.000 79.78033  ? 137 LYS A NZ   1 
ATOM   2115 H H    . LYS A 1 137 ? -13.19037 -6.21181  -17.53171 1.000 53.76899  ? 137 LYS A H    1 
ATOM   2116 H HA   . LYS A 1 137 ? -10.74165 -6.84977  -18.47731 1.000 50.02659  ? 137 LYS A HA   1 
ATOM   2117 H HB2  . LYS A 1 137 ? -13.15042 -7.63425  -19.67313 1.000 59.13275  ? 137 LYS A HB2  1 
ATOM   2118 H HB3  . LYS A 1 137 ? -11.74089 -8.36023  -19.78080 1.000 59.13275  ? 137 LYS A HB3  1 
ATOM   2119 H HG2  . LYS A 1 137 ? -12.18037 -8.67880  -17.29459 1.000 68.33508  ? 137 LYS A HG2  1 
ATOM   2120 H HG3  . LYS A 1 137 ? -13.67756 -8.67340  -17.82732 1.000 68.33508  ? 137 LYS A HG3  1 
ATOM   2121 H HD2  . LYS A 1 137 ? -13.49793 -10.70831 -18.51542 1.000 78.17854  ? 137 LYS A HD2  1 
ATOM   2122 H HD3  . LYS A 1 137 ? -12.16841 -10.37040 -19.31766 1.000 78.17854  ? 137 LYS A HD3  1 
ATOM   2123 H HE2  . LYS A 1 137 ? -11.45493 -11.90526 -17.86189 1.000 85.99131  ? 137 LYS A HE2  1 
ATOM   2124 H HE3  . LYS A 1 137 ? -11.06027 -10.55210 -17.12800 1.000 85.99131  ? 137 LYS A HE3  1 
ATOM   2125 H HZ1  . LYS A 1 137 ? -12.06990 -11.98052 -15.67467 1.000 95.73017  ? 137 LYS A HZ1  1 
ATOM   2126 H HZ2  . LYS A 1 137 ? -12.90715 -10.80689 -15.81587 1.000 95.73017  ? 137 LYS A HZ2  1 
ATOM   2127 H HZ3  . LYS A 1 137 ? -13.26870 -12.03934 -16.48568 1.000 95.73017  ? 137 LYS A HZ3  1 
ATOM   2128 N N    . GLY A 1 138 ? -10.60056 -4.67985  -19.71215 1.000 43.58081  ? 138 GLY A N    1 
ATOM   2129 C CA   . GLY A 1 138 ? -10.51338 -3.50454  -20.53129 1.000 40.55831  ? 138 GLY A CA   1 
ATOM   2130 C C    . GLY A 1 138 ? -9.45522  -3.58603  -21.60344 1.000 34.19348  ? 138 GLY A C    1 
ATOM   2131 O O    . GLY A 1 138 ? -8.94042  -4.67382  -21.93936 1.000 39.00649  ? 138 GLY A O    1 
ATOM   2132 H H    . GLY A 1 138 ? -9.92231  -4.78723  -19.19441 1.000 52.29074  ? 138 GLY A H    1 
ATOM   2133 H HA2  . GLY A 1 138 ? -11.36862 -3.35829  -20.96497 1.000 48.66375  ? 138 GLY A HA2  1 
ATOM   2134 H HA3  . GLY A 1 138 ? -10.31059 -2.74163  -19.96761 1.000 48.66375  ? 138 GLY A HA3  1 
ATOM   2135 N N    . SER A 1 139 ? -9.11714  -2.43212  -22.17033 1.000 33.84933  ? 139 SER A N    1 
ATOM   2136 C CA   . SER A 1 139 ? -8.09142  -2.30133  -23.20355 1.000 36.90610  ? 139 SER A CA   1 
ATOM   2137 C C    . SER A 1 139 ? -7.29137  -1.04025  -22.88381 1.000 36.28375  ? 139 SER A C    1 
ATOM   2138 O O    . SER A 1 139 ? -7.74289  0.07643   -23.16081 1.000 33.03077  ? 139 SER A O    1 
ATOM   2139 C CB   . SER A 1 139 ? -8.71125  -2.23966  -24.59560 1.000 35.49128  ? 139 SER A CB   1 
ATOM   2140 O OG   . SER A 1 139 ? -7.71799  -2.12012  -25.60187 1.000 34.92572  ? 139 SER A OG   1 
ATOM   2141 H H    . SER A 1 139 ? -9.48134  -1.68028  -21.96613 1.000 40.61297  ? 139 SER A H    1 
ATOM   2142 H HA   . SER A 1 139 ? -7.49429  -3.06520  -23.17457 1.000 44.28110  ? 139 SER A HA   1 
ATOM   2143 H HB2  . SER A 1 139 ? -9.21684  -3.05302  -24.74963 1.000 42.58331  ? 139 SER A HB2  1 
ATOM   2144 H HB3  . SER A 1 139 ? -9.29918  -1.46960  -24.64282 1.000 42.58331  ? 139 SER A HB3  1 
ATOM   2145 H HG   . SER A 1 139 ? -7.20767  -2.78705  -25.58249 1.000 41.90464  ? 139 SER A HG   1 
ATOM   2146 N N    . PHE A 1 140 ? -6.10588  -1.22649  -22.30126 1.000 32.77979  ? 140 PHE A N    1 
ATOM   2147 C CA   . PHE A 1 140 ? -5.31775  -0.13174  -21.75089 1.000 35.39986  ? 140 PHE A CA   1 
ATOM   2148 C C    . PHE A 1 140 ? -3.83926  -0.37516  -22.00586 1.000 39.57923  ? 140 PHE A C    1 
ATOM   2149 O O    . PHE A 1 140 ? -3.30949  -1.42534  -21.63225 1.000 39.80088  ? 140 PHE A O    1 
ATOM   2150 C CB   . PHE A 1 140 ? -5.55030  0.01439   -20.23817 1.000 39.06901  ? 140 PHE A CB   1 
ATOM   2151 C CG   . PHE A 1 140 ? -6.91716  0.52124   -19.87347 1.000 38.57976  ? 140 PHE A CG   1 
ATOM   2152 C CD1  . PHE A 1 140 ? -7.36154  1.75201   -20.32791 1.000 36.04983  ? 140 PHE A CD1  1 
ATOM   2153 C CD2  . PHE A 1 140 ? -7.75031  -0.22548  -19.06067 1.000 41.02053  ? 140 PHE A CD2  1 
ATOM   2154 C CE1  . PHE A 1 140 ? -8.61812  2.21798   -19.98979 1.000 43.28534  ? 140 PHE A CE1  1 
ATOM   2155 C CE2  . PHE A 1 140 ? -9.00491  0.23800   -18.71575 1.000 35.11338  ? 140 PHE A CE2  1 
ATOM   2156 C CZ   . PHE A 1 140 ? -9.43919  1.45918   -19.18041 1.000 38.97789  ? 140 PHE A CZ   1 
ATOM   2157 H H    . PHE A 1 140 ? -5.73169  -1.99572  -22.21247 1.000 39.32951  ? 140 PHE A H    1 
ATOM   2158 H HA   . PHE A 1 140 ? -5.57535  0.68954   -22.19815 1.000 42.47360  ? 140 PHE A HA   1 
ATOM   2159 H HB2  . PHE A 1 140 ? -5.43729  -0.85414  -19.82129 1.000 46.87658  ? 140 PHE A HB2  1 
ATOM   2160 H HB3  . PHE A 1 140 ? -4.89969  0.64005   -19.88299 1.000 46.87658  ? 140 PHE A HB3  1 
ATOM   2161 H HD1  . PHE A 1 140 ? -6.80832  2.27051   -20.86644 1.000 43.25357  ? 140 PHE A HD1  1 
ATOM   2162 H HD2  . PHE A 1 140 ? -7.46215  -1.05037  -18.74219 1.000 49.21840  ? 140 PHE A HD2  1 
ATOM   2163 H HE1  . PHE A 1 140 ? -8.91005  3.04191   -20.30731 1.000 51.93618  ? 140 PHE A HE1  1 
ATOM   2164 H HE2  . PHE A 1 140 ? -9.55622  -0.27469  -18.16975 1.000 42.12983  ? 140 PHE A HE2  1 
ATOM   2165 H HZ   . PHE A 1 140 ? -10.28396 1.77206   -18.94939 1.000 46.76724  ? 140 PHE A HZ   1 
ATOM   2166 N N    . LEU A 1 141 ? -3.17688  0.59962   -22.62550 1.000 36.60625  ? 141 LEU A N    1 
ATOM   2167 C CA   . LEU A 1 141 ? -1.73285  0.59523   -22.77650 1.000 40.85684  ? 141 LEU A CA   1 
ATOM   2168 C C    . LEU A 1 141 ? -1.09150  1.53249   -21.75712 1.000 44.70192  ? 141 LEU A C    1 
ATOM   2169 O O    . LEU A 1 141 ? -1.76870  2.24248   -21.00659 1.000 41.52591  ? 141 LEU A O    1 
ATOM   2170 C CB   . LEU A 1 141 ? -1.33299  1.01748   -24.18869 1.000 33.68277  ? 141 LEU A CB   1 
ATOM   2171 C CG   . LEU A 1 141 ? -1.93383  0.22088   -25.34291 1.000 44.10013  ? 141 LEU A CG   1 
ATOM   2172 C CD1  . LEU A 1 141 ? -1.68597  0.95700   -26.65271 1.000 44.61680  ? 141 LEU A CD1  1 
ATOM   2173 C CD2  . LEU A 1 141 ? -1.36355  -1.18655  -25.39014 1.000 37.58568  ? 141 LEU A CD2  1 
ATOM   2174 H H    . LEU A 1 141 ? -3.55548  1.28887   -22.97362 1.000 43.92127  ? 141 LEU A H    1 
ATOM   2175 H HA   . LEU A 1 141 ? -1.42053  -0.30934  -22.61808 1.000 49.02198  ? 141 LEU A HA   1 
ATOM   2176 H HB2  . LEU A 1 141 ? -1.60166  1.94135   -24.31182 1.000 40.41310  ? 141 LEU A HB2  1 
ATOM   2177 H HB3  . LEU A 1 141 ? -0.36891  0.93972   -24.26225 1.000 40.41310  ? 141 LEU A HB3  1 
ATOM   2178 H HG   . LEU A 1 141 ? -2.89120  0.13446   -25.21300 1.000 52.91392  ? 141 LEU A HG   1 
ATOM   2179 H HD11 . LEU A 1 141 ? -2.43371  1.54938   -26.82843 1.000 53.53393  ? 141 LEU A HD11 1 
ATOM   2180 H HD12 . LEU A 1 141 ? -0.86731  1.47155   -26.57576 1.000 53.53393  ? 141 LEU A HD12 1 
ATOM   2181 H HD13 . LEU A 1 141 ? -1.60270  0.30804   -27.36882 1.000 53.53393  ? 141 LEU A HD13 1 
ATOM   2182 H HD21 . LEU A 1 141 ? -1.84424  -1.69980  -26.05828 1.000 45.09658  ? 141 LEU A HD21 1 
ATOM   2183 H HD22 . LEU A 1 141 ? -0.42320  -1.13861  -25.62328 1.000 45.09658  ? 141 LEU A HD22 1 
ATOM   2184 H HD23 . LEU A 1 141 ? -1.46759  -1.59887  -24.51833 1.000 45.09658  ? 141 LEU A HD23 1 
ATOM   2185 N N    . ASN A 1 142 ? 0.24067   1.54141   -21.74427 1.000 48.45930  ? 142 ASN A N    1 
ATOM   2186 C CA   . ASN A 1 142 ? 0.97124   2.46926   -20.89396 1.000 39.93578  ? 142 ASN A CA   1 
ATOM   2187 C C    . ASN A 1 142 ? 0.63343   3.90288   -21.29005 1.000 43.44414  ? 142 ASN A C    1 
ATOM   2188 O O    . ASN A 1 142 ? 0.64457   4.25362   -22.47375 1.000 43.84028  ? 142 ASN A O    1 
ATOM   2189 C CB   . ASN A 1 142 ? 2.47495   2.22025   -21.00235 1.000 45.05888  ? 142 ASN A CB   1 
ATOM   2190 C CG   . ASN A 1 142 ? 3.27329   3.07049   -20.03419 1.000 57.44646  ? 142 ASN A CG   1 
ATOM   2191 O OD1  . ASN A 1 142 ? 2.82354   3.35168   -18.92265 1.000 60.59040  ? 142 ASN A OD1  1 
ATOM   2192 N ND2  . ASN A 1 142 ? 4.45894   3.49435   -20.45498 1.000 62.02139  ? 142 ASN A ND2  1 
ATOM   2193 H H    . ASN A 1 142 ? 0.73894   1.02305   -22.21611 1.000 58.14493  ? 142 ASN A H    1 
ATOM   2194 H HA   . ASN A 1 142 ? 0.71850   2.33398   -19.96728 1.000 47.91671  ? 142 ASN A HA   1 
ATOM   2195 H HB2  . ASN A 1 142 ? 2.65724   1.28804   -20.80573 1.000 54.06443  ? 142 ASN A HB2  1 
ATOM   2196 H HB3  . ASN A 1 142 ? 2.76778   2.43290   -21.90231 1.000 54.06443  ? 142 ASN A HB3  1 
ATOM   2197 H HD21 . ASN A 1 142 ? 4.94909   3.97983   -19.94151 1.000 74.41944  ? 142 ASN A HD21 1 
ATOM   2198 H HD22 . ASN A 1 142 ? 4.73684   3.28343   -21.24104 1.000 74.41944  ? 142 ASN A HD22 1 
ATOM   2199 N N    . GLY A 1 143 ? 0.31466   4.72726   -20.29420 1.000 41.21762  ? 143 GLY A N    1 
ATOM   2200 C CA   . GLY A 1 143 ? -0.14707  6.07876   -20.52643 1.000 39.78195  ? 143 GLY A CA   1 
ATOM   2201 C C    . GLY A 1 143 ? -1.65157  6.24690   -20.52227 1.000 40.31439  ? 143 GLY A C    1 
ATOM   2202 O O    . GLY A 1 143 ? -2.13029  7.37441   -20.69268 1.000 37.43182  ? 143 GLY A O    1 
ATOM   2203 H H    . GLY A 1 143 ? 0.36078   4.51622   -19.46177 1.000 49.45492  ? 143 GLY A H    1 
ATOM   2204 H HA2  . GLY A 1 143 ? 0.21683   6.65426   -19.83559 1.000 47.73211  ? 143 GLY A HA2  1 
ATOM   2205 H HA3  . GLY A 1 143 ? 0.18133   6.37509   -21.38970 1.000 47.73211  ? 143 GLY A HA3  1 
ATOM   2206 N N    . SER A 1 144 ? -2.41159  5.16454   -20.33975 1.000 47.14547  ? 144 SER A N    1 
ATOM   2207 C CA   . SER A 1 144 ? -3.86631  5.23843   -20.29445 1.000 42.52696  ? 144 SER A CA   1 
ATOM   2208 C C    . SER A 1 144 ? -4.39869  5.62375   -18.92166 1.000 38.23737  ? 144 SER A C    1 
ATOM   2209 O O    . SER A 1 144 ? -5.60092  5.88579   -18.79833 1.000 35.07599  ? 144 SER A O    1 
ATOM   2210 C CB   . SER A 1 144 ? -4.47895  3.89558   -20.70970 1.000 34.83320  ? 144 SER A CB   1 
ATOM   2211 O OG   . SER A 1 144 ? -4.05426  2.85313   -19.84802 1.000 44.63160  ? 144 SER A OG   1 
ATOM   2212 H H    . SER A 1 144 ? -2.10197  4.36858   -20.23883 1.000 56.56833  ? 144 SER A H    1 
ATOM   2213 H HA   . SER A 1 144 ? -4.15607  5.91130   -20.93021 1.000 51.02613  ? 144 SER A HA   1 
ATOM   2214 H HB2  . SER A 1 144 ? -5.44562  3.96427   -20.66806 1.000 41.79361  ? 144 SER A HB2  1 
ATOM   2215 H HB3  . SER A 1 144 ? -4.19975  3.68881   -21.61535 1.000 41.79361  ? 144 SER A HB3  1 
ATOM   2216 H HG   . SER A 1 144 ? -4.20909  3.06003   -19.04876 1.000 53.55170  ? 144 SER A HG   1 
ATOM   2217 N N    . CYS A 1 145 ? -3.54442  5.66167   -17.89682 1.000 41.69884  ? 145 CYS A N    1 
ATOM   2218 C CA   . CYS A 1 145 ? -3.99155  6.03546   -16.56154 1.000 41.18421  ? 145 CYS A CA   1 
ATOM   2219 C C    . CYS A 1 145 ? -4.69427  7.38549   -16.60139 1.000 36.99191  ? 145 CYS A C    1 
ATOM   2220 O O    . CYS A 1 145 ? -4.26910  8.30514   -17.30563 1.000 36.99205  ? 145 CYS A O    1 
ATOM   2221 C CB   . CYS A 1 145 ? -2.81003  6.09749   -15.59187 1.000 46.93948  ? 145 CYS A CB   1 
ATOM   2222 S SG   . CYS A 1 145 ? -1.79855  4.61212   -15.54438 1.000 69.63275  ? 145 CYS A SG   1 
ATOM   2223 H H    . CYS A 1 145 ? -2.70647  5.47600   -17.95125 1.000 50.03238  ? 145 CYS A H    1 
ATOM   2224 H HA   . CYS A 1 145 ? -4.61123  5.36408   -16.23575 1.000 49.41482  ? 145 CYS A HA   1 
ATOM   2225 H HB2  . CYS A 1 145 ? -2.23547  6.83405   -15.85311 1.000 56.32115  ? 145 CYS A HB2  1 
ATOM   2226 H HB3  . CYS A 1 145 ? -3.15347  6.24589   -14.69693 1.000 56.32115  ? 145 CYS A HB3  1 
ATOM   2227 N N    . GLY A 1 146 ? -5.77705  7.49836   -15.83451 1.000 32.52829  ? 146 GLY A N    1 
ATOM   2228 C CA   . GLY A 1 146 ? -6.59064  8.68901   -15.82192 1.000 36.55302  ? 146 GLY A CA   1 
ATOM   2229 C C    . GLY A 1 146 ? -7.78476  8.64370   -16.74879 1.000 35.24941  ? 146 GLY A C    1 
ATOM   2230 O O    . GLY A 1 146 ? -8.68506  9.48239   -16.61843 1.000 38.19723  ? 146 GLY A O    1 
ATOM   2231 H H    . GLY A 1 146 ? -6.05834  6.88118   -15.30578 1.000 39.02772  ? 146 GLY A H    1 
ATOM   2232 H HA2  . GLY A 1 146 ? -6.91930  8.83263   -14.92067 1.000 43.85739  ? 146 GLY A HA2  1 
ATOM   2233 H HA3  . GLY A 1 146 ? -6.04119  9.44493   -16.08191 1.000 43.85739  ? 146 GLY A HA3  1 
ATOM   2234 N N    . SER A 1 147 ? -7.80403  7.70673   -17.69574 1.000 32.98439  ? 147 SER A N    1 
ATOM   2235 C CA   . SER A 1 147 ? -9.02446  7.41154   -18.43157 1.000 31.23684  ? 147 SER A CA   1 
ATOM   2236 C C    . SER A 1 147 ? -10.12330 7.03752   -17.44671 1.000 35.46255  ? 147 SER A C    1 
ATOM   2237 O O    . SER A 1 147 ? -9.87406  6.37548   -16.43461 1.000 30.75262  ? 147 SER A O    1 
ATOM   2238 C CB   . SER A 1 147 ? -8.78561  6.27538   -19.42612 1.000 32.76045  ? 147 SER A CB   1 
ATOM   2239 O OG   . SER A 1 147 ? -7.80971  6.64274   -20.38696 1.000 29.86093  ? 147 SER A OG   1 
ATOM   2240 H H    . SER A 1 147 ? -7.12599  7.23153   -17.92821 1.000 39.57504  ? 147 SER A H    1 
ATOM   2241 H HA   . SER A 1 147 ? -9.30628  8.18744   -18.94094 1.000 37.47798  ? 147 SER A HA   1 
ATOM   2242 H HB2  . SER A 1 147 ? -8.47490  5.49342   -18.94354 1.000 39.30632  ? 147 SER A HB2  1 
ATOM   2243 H HB3  . SER A 1 147 ? -9.61788  6.07477   -19.88217 1.000 39.30632  ? 147 SER A HB3  1 
ATOM   2244 H HG   . SER A 1 147 ? -7.07656  6.79729   -20.00721 1.000 35.82689  ? 147 SER A HG   1 
ATOM   2245 N N    . VAL A 1 148 ? -11.34321 7.47249   -17.73760 1.000 35.75007  ? 148 VAL A N    1 
ATOM   2246 C CA   . VAL A 1 148 ? -12.43208 7.36160   -16.77992 1.000 34.12776  ? 148 VAL A CA   1 
ATOM   2247 C C    . VAL A 1 148 ? -13.56759 6.55010   -17.37831 1.000 31.85475  ? 148 VAL A C    1 
ATOM   2248 O O    . VAL A 1 148 ? -13.72904 6.45454   -18.59958 1.000 34.25707  ? 148 VAL A O    1 
ATOM   2249 C CB   . VAL A 1 148 ? -12.93739 8.75038   -16.33122 1.000 29.53598  ? 148 VAL A CB   1 
ATOM   2250 C CG1  . VAL A 1 148 ? -11.78819 9.56091   -15.75439 1.000 36.45891  ? 148 VAL A CG1  1 
ATOM   2251 C CG2  . VAL A 1 148 ? -13.58792 9.48291   -17.48856 1.000 28.66349  ? 148 VAL A CG2  1 
ATOM   2252 H H    . VAL A 1 148 ? -11.56370 7.83607   -18.48513 1.000 42.89385  ? 148 VAL A H    1 
ATOM   2253 H HA   . VAL A 1 148 ? -12.10869 6.87896   -16.00315 1.000 40.94709  ? 148 VAL A HA   1 
ATOM   2254 H HB   . VAL A 1 148 ? -13.60838 8.63691   -15.63999 1.000 35.43694  ? 148 VAL A HB   1 
ATOM   2255 H HG11 . VAL A 1 148 ? -11.08054 8.95597   -15.48204 1.000 43.74446  ? 148 VAL A HG11 1 
ATOM   2256 H HG12 . VAL A 1 148 ? -11.45928 10.17022  -16.43370 1.000 43.74446  ? 148 VAL A HG12 1 
ATOM   2257 H HG13 . VAL A 1 148 ? -12.10846 10.06174  -14.98791 1.000 43.74446  ? 148 VAL A HG13 1 
ATOM   2258 H HG21 . VAL A 1 148 ? -13.10267 9.27991   -18.30356 1.000 34.38996  ? 148 VAL A HG21 1 
ATOM   2259 H HG22 . VAL A 1 148 ? -14.50893 9.18969   -17.57022 1.000 34.38996  ? 148 VAL A HG22 1 
ATOM   2260 H HG23 . VAL A 1 148 ? -13.55862 10.43681  -17.31503 1.000 34.38996  ? 148 VAL A HG23 1 
ATOM   2261 N N    . GLY A 1 149 ? -14.34791 5.94758   -16.48955 1.000 32.32536  ? 149 GLY A N    1 
ATOM   2262 C CA   . GLY A 1 149 ? -15.57386 5.26635   -16.85152 1.000 35.38183  ? 149 GLY A CA   1 
ATOM   2263 C C    . GLY A 1 149 ? -16.75057 6.07725   -16.34759 1.000 32.68854  ? 149 GLY A C    1 
ATOM   2264 O O    . GLY A 1 149 ? -16.64073 6.79635   -15.35222 1.000 32.99327  ? 149 GLY A O    1 
ATOM   2265 H H    . GLY A 1 149 ? -14.17952 5.92144   -15.64660 1.000 38.78420  ? 149 GLY A H    1 
ATOM   2266 H HA2  . GLY A 1 149 ? -15.63567 5.17696   -17.81541 1.000 42.45197  ? 149 GLY A HA2  1 
ATOM   2267 H HA3  . GLY A 1 149 ? -15.59783 4.38353   -16.45031 1.000 42.45197  ? 149 GLY A HA3  1 
ATOM   2268 N N    . PHE A 1 150 ? -17.88075 5.96693   -17.04139 1.000 29.42748  ? 150 PHE A N    1 
ATOM   2269 C CA   . PHE A 1 150 ? -19.00700 6.83938   -16.74729 1.000 36.90288  ? 150 PHE A CA   1 
ATOM   2270 C C    . PHE A 1 150 ? -20.30802 6.20820   -17.21689 1.000 35.53049  ? 150 PHE A C    1 
ATOM   2271 O O    . PHE A 1 150 ? -20.32380 5.33044   -18.08388 1.000 36.95153  ? 150 PHE A O    1 
ATOM   2272 C CB   . PHE A 1 150 ? -18.82548 8.20836   -17.41353 1.000 34.89813  ? 150 PHE A CB   1 
ATOM   2273 C CG   . PHE A 1 150 ? -18.68571 8.13680   -18.91062 1.000 33.17591  ? 150 PHE A CG   1 
ATOM   2274 C CD1  . PHE A 1 150 ? -17.45461 7.86954   -19.49517 1.000 34.71445  ? 150 PHE A CD1  1 
ATOM   2275 C CD2  . PHE A 1 150 ? -19.78309 8.33589   -19.73387 1.000 29.80734  ? 150 PHE A CD2  1 
ATOM   2276 C CE1  . PHE A 1 150 ? -17.32071 7.80163   -20.87552 1.000 30.39957  ? 150 PHE A CE1  1 
ATOM   2277 C CE2  . PHE A 1 150 ? -19.65677 8.27209   -21.11503 1.000 31.51159  ? 150 PHE A CE2  1 
ATOM   2278 C CZ   . PHE A 1 150 ? -18.42392 8.00424   -21.68603 1.000 33.23283  ? 150 PHE A CZ   1 
ATOM   2279 H H    . PHE A 1 150 ? -18.01542 5.40301   -17.67657 1.000 35.30675  ? 150 PHE A H    1 
ATOM   2280 H HA   . PHE A 1 150 ? -19.06611 6.94464   -15.78483 1.000 44.27722  ? 150 PHE A HA   1 
ATOM   2281 H HB2  . PHE A 1 150 ? -19.59932 8.75807   -17.21380 1.000 41.87152  ? 150 PHE A HB2  1 
ATOM   2282 H HB3  . PHE A 1 150 ? -18.02331 8.62383   -17.06024 1.000 41.87152  ? 150 PHE A HB3  1 
ATOM   2283 H HD1  . PHE A 1 150 ? -16.70989 7.73423   -18.95481 1.000 41.65111  ? 150 PHE A HD1  1 
ATOM   2284 H HD2  . PHE A 1 150 ? -20.61409 8.51438   -19.35641 1.000 35.76258  ? 150 PHE A HD2  1 
ATOM   2285 H HE1  . PHE A 1 150 ? -16.49110 7.62032   -21.25470 1.000 36.47326  ? 150 PHE A HE1  1 
ATOM   2286 H HE2  . PHE A 1 150 ? -20.40016 8.40924   -21.65675 1.000 37.80768  ? 150 PHE A HE2  1 
ATOM   2287 H HZ   . PHE A 1 150 ? -18.33767 7.96067   -22.61100 1.000 39.87317  ? 150 PHE A HZ   1 
ATOM   2288 N N    . ASN A 1 151 ? -21.40066 6.67498   -16.61709 1.000 36.99493  ? 151 ASN A N    1 
ATOM   2289 C CA   . ASN A 1 151 ? -22.75556 6.46278   -17.10091 1.000 38.58453  ? 151 ASN A CA   1 
ATOM   2290 C C    . ASN A 1 151 ? -23.40765 7.82523   -17.29792 1.000 42.14643  ? 151 ASN A C    1 
ATOM   2291 O O    . ASN A 1 151 ? -23.01504 8.81327   -16.67221 1.000 46.63622  ? 151 ASN A O    1 
ATOM   2292 C CB   . ASN A 1 151 ? -23.57530 5.61307   -16.12337 1.000 43.56276  ? 151 ASN A CB   1 
ATOM   2293 C CG   . ASN A 1 151 ? -23.29496 4.12712   -16.26621 1.000 34.60424  ? 151 ASN A CG   1 
ATOM   2294 O OD1  . ASN A 1 151 ? -23.75391 3.49572   -17.20932 1.000 51.27100  ? 151 ASN A OD1  1 
ATOM   2295 N ND2  . ASN A 1 151 ? -22.55105 3.56227   -15.32405 1.000 35.84313  ? 151 ASN A ND2  1 
ATOM   2296 H H    . ASN A 1 151 ? -21.37806 7.13946   -15.89366 1.000 44.38769  ? 151 ASN A H    1 
ATOM   2297 H HA   . ASN A 1 151 ? -22.74409 5.99019   -17.94792 1.000 46.29521  ? 151 ASN A HA   1 
ATOM   2298 H HB2  . ASN A 1 151 ? -23.35608 5.87458   -15.21537 1.000 52.26909  ? 151 ASN A HB2  1 
ATOM   2299 H HB3  . ASN A 1 151 ? -24.51943 5.75858   -16.29175 1.000 52.26909  ? 151 ASN A HB3  1 
ATOM   2300 H HD21 . ASN A 1 151 ? -22.36806 2.72302   -15.36619 1.000 43.00553  ? 151 ASN A HD21 1 
ATOM   2301 H HD22 . ASN A 1 151 ? -22.25181 4.03536   -14.67118 1.000 43.00553  ? 151 ASN A HD22 1 
ATOM   2302 N N    . ILE A 1 152 ? -24.40236 7.88272   -18.18197 1.000 44.78733  ? 152 ILE A N    1 
ATOM   2303 C CA   . ILE A 1 152 ? -25.11181 9.12240   -18.47931 1.000 45.56110  ? 152 ILE A CA   1 
ATOM   2304 C C    . ILE A 1 152 ? -26.58838 8.92901   -18.16303 1.000 50.16113  ? 152 ILE A C    1 
ATOM   2305 O O    . ILE A 1 152 ? -27.21235 7.97455   -18.64200 1.000 40.68594  ? 152 ILE A O    1 
ATOM   2306 C CB   . ILE A 1 152 ? -24.91201 9.55485   -19.94393 1.000 44.45034  ? 152 ILE A CB   1 
ATOM   2307 C CG1  . ILE A 1 152 ? -23.41612 9.68794   -20.24896 1.000 51.86162  ? 152 ILE A CG1  1 
ATOM   2308 C CG2  . ILE A 1 152 ? -25.62403 10.87784  -20.21846 1.000 44.75552  ? 152 ILE A CG2  1 
ATOM   2309 C CD1  . ILE A 1 152 ? -23.10915 10.21353  -21.63656 1.000 49.13362  ? 152 ILE A CD1  1 
ATOM   2310 H H    . ILE A 1 152 ? -24.68721 7.20492   -18.62812 1.000 53.73857  ? 152 ILE A H    1 
ATOM   2311 H HA   . ILE A 1 152 ? -24.77354 9.82682   -17.90462 1.000 54.66709  ? 152 ILE A HA   1 
ATOM   2312 H HB   . ILE A 1 152 ? -25.29561 8.87440   -20.51903 1.000 53.33418  ? 152 ILE A HB   1 
ATOM   2313 H HG12 . ILE A 1 152 ? -23.02238 10.30090  -19.60853 1.000 62.22772  ? 152 ILE A HG12 1 
ATOM   2314 H HG13 . ILE A 1 152 ? -23.00411 8.81354   -20.16787 1.000 62.22772  ? 152 ILE A HG13 1 
ATOM   2315 H HG21 . ILE A 1 152 ? -25.56317 11.07865  -21.16549 1.000 53.70040  ? 152 ILE A HG21 1 
ATOM   2316 H HG22 . ILE A 1 152 ? -26.55448 10.79594  -19.95682 1.000 53.70040  ? 152 ILE A HG22 1 
ATOM   2317 H HG23 . ILE A 1 152 ? -25.19611 11.57959  -19.70336 1.000 53.70040  ? 152 ILE A HG23 1 
ATOM   2318 H HD11 . ILE A 1 152 ? -23.68038 9.76328   -22.27833 1.000 58.95412  ? 152 ILE A HD11 1 
ATOM   2319 H HD12 . ILE A 1 152 ? -23.27744 11.16861  -21.65687 1.000 58.95412  ? 152 ILE A HD12 1 
ATOM   2320 H HD13 . ILE A 1 152 ? -22.17768 10.03735  -21.84208 1.000 58.95412  ? 152 ILE A HD13 1 
ATOM   2321 N N    . ASP A 1 153 ? -27.13799 9.83355   -17.34884 1.000 57.86506  ? 153 ASP A N    1 
ATOM   2322 C CA   . ASP A 1 153 ? -28.56309 9.87464   -17.02170 1.000 60.80733  ? 153 ASP A CA   1 
ATOM   2323 C C    . ASP A 1 153 ? -29.14246 11.12186  -17.68857 1.000 63.19007  ? 153 ASP A C    1 
ATOM   2324 O O    . ASP A 1 153 ? -29.04587 12.23032  -17.15229 1.000 57.64431  ? 153 ASP A O    1 
ATOM   2325 C CB   . ASP A 1 153 ? -28.78475 9.88488   -15.51119 1.000 65.04652  ? 153 ASP A CB   1 
ATOM   2326 C CG   . ASP A 1 153 ? -30.23353 9.62025   -15.13346 1.000 82.53227  ? 153 ASP A CG   1 
ATOM   2327 O OD1  . ASP A 1 153 ? -31.04640 9.36864   -16.04921 1.000 69.27625  ? 153 ASP A OD1  1 
ATOM   2328 O OD2  . ASP A 1 153 ? -30.55959 9.66251   -13.92633 1.000 83.04178  ? 153 ASP A OD2  1 
ATOM   2329 H H    . ASP A 1 153 ? -26.68787 10.45520  -16.96084 1.000 69.43185  ? 153 ASP A H    1 
ATOM   2330 H HA   . ASP A 1 153 ? -29.00532 9.08931   -17.38031 1.000 72.96257  ? 153 ASP A HA   1 
ATOM   2331 H HB2  . ASP A 1 153 ? -28.23711 9.19453   -15.10573 1.000 78.04959  ? 153 ASP A HB2  1 
ATOM   2332 H HB3  . ASP A 1 153 ? -28.53622 10.75433  -15.16020 1.000 78.04959  ? 153 ASP A HB3  1 
ATOM   2333 N N    . TYR A 1 154 ? -29.74526 10.92992  -18.86106 1.000 58.01131  ? 154 TYR A N    1 
ATOM   2334 C CA   . TYR A 1 154 ? -30.22683 12.02338  -19.69649 1.000 55.63465  ? 154 TYR A CA   1 
ATOM   2335 C C    . TYR A 1 154 ? -29.11574 13.01662  -20.01537 1.000 59.66911  ? 154 TYR A C    1 
ATOM   2336 O O    . TYR A 1 154 ? -28.55086 12.99059  -21.11318 1.000 54.55476  ? 154 TYR A O    1 
ATOM   2337 C CB   . TYR A 1 154 ? -31.39264 12.76169  -19.03668 1.000 60.32766  ? 154 TYR A CB   1 
ATOM   2338 C CG   . TYR A 1 154 ? -31.86882 13.93592  -19.86771 1.000 64.99603  ? 154 TYR A CG   1 
ATOM   2339 C CD1  . TYR A 1 154 ? -32.15834 13.77639  -21.21763 1.000 71.93004  ? 154 TYR A CD1  1 
ATOM   2340 C CD2  . TYR A 1 154 ? -32.01939 15.20043  -19.31142 1.000 52.51645  ? 154 TYR A CD2  1 
ATOM   2341 C CE1  . TYR A 1 154 ? -32.58738 14.83715  -21.98863 1.000 70.04067  ? 154 TYR A CE1  1 
ATOM   2342 C CE2  . TYR A 1 154 ? -32.45098 16.27030  -20.07693 1.000 58.44506  ? 154 TYR A CE2  1 
ATOM   2343 C CZ   . TYR A 1 154 ? -32.73116 16.08209  -21.41634 1.000 71.04476  ? 154 TYR A CZ   1 
ATOM   2344 O OH   . TYR A 1 154 ? -33.16348 17.13747  -22.18926 1.000 76.02780  ? 154 TYR A OH   1 
ATOM   2345 H H    . TYR A 1 154 ? -29.89045 10.15417  -19.20272 1.000 69.60735  ? 154 TYR A H    1 
ATOM   2346 H HA   . TYR A 1 154 ? -30.54246 11.63529  -20.52755 1.000 66.75535  ? 154 TYR A HA   1 
ATOM   2347 H HB2  . TYR A 1 154 ? -32.13565 12.14810  -18.92559 1.000 72.38696  ? 154 TYR A HB2  1 
ATOM   2348 H HB3  . TYR A 1 154 ? -31.10794 13.09786  -18.17248 1.000 72.38696  ? 154 TYR A HB3  1 
ATOM   2349 H HD1  . TYR A 1 154 ? -32.06100 12.93833  -21.60888 1.000 86.30982  ? 154 TYR A HD1  1 
ATOM   2350 H HD2  . TYR A 1 154 ? -31.82724 15.33007  -18.41077 1.000 63.01352  ? 154 TYR A HD2  1 
ATOM   2351 H HE1  . TYR A 1 154 ? -32.77855 14.71237  -22.89018 1.000 84.04258  ? 154 TYR A HE1  1 
ATOM   2352 H HE2  . TYR A 1 154 ? -32.55164 17.11071  -19.69159 1.000 70.12784  ? 154 TYR A HE2  1 
ATOM   2353 H HH   . TYR A 1 154 ? -33.69214 16.86241  -22.78126 1.000 91.22713  ? 154 TYR A HH   1 
ATOM   2354 N N    . ASP A 1 155 ? -28.81195 13.91154  -19.07262 1.000 55.65919  ? 155 ASP A N    1 
ATOM   2355 C CA   . ASP A 1 155 ? -27.75933 14.89720  -19.26201 1.000 59.23472  ? 155 ASP A CA   1 
ATOM   2356 C C    . ASP A 1 155 ? -26.74434 14.91680  -18.12824 1.000 46.76994  ? 155 ASP A C    1 
ATOM   2357 O O    . ASP A 1 155 ? -25.82285 15.73868  -18.16335 1.000 51.06395  ? 155 ASP A O    1 
ATOM   2358 C CB   . ASP A 1 155 ? -28.35779 16.30447  -19.41246 1.000 58.64465  ? 155 ASP A CB   1 
ATOM   2359 C CG   . ASP A 1 155 ? -28.93324 16.83458  -18.11243 1.000 65.19185  ? 155 ASP A CG   1 
ATOM   2360 O OD1  . ASP A 1 155 ? -29.73199 16.11559  -17.47387 1.000 69.99768  ? 155 ASP A OD1  1 
ATOM   2361 O OD2  . ASP A 1 155 ? -28.57549 17.96668  -17.72375 1.000 54.64681  ? 155 ASP A OD2  1 
ATOM   2362 H H    . ASP A 1 155 ? -29.20706 13.96446  -18.31059 1.000 66.78480  ? 155 ASP A H    1 
ATOM   2363 H HA   . ASP A 1 155 ? -27.28912 14.68514  -20.08350 1.000 71.07544  ? 155 ASP A HA   1 
ATOM   2364 H HB2  . ASP A 1 155 ? -27.66275 16.91476  -19.70466 1.000 70.36735  ? 155 ASP A HB2  1 
ATOM   2365 H HB3  . ASP A 1 155 ? -29.07200 16.27658  -20.06823 1.000 70.36735  ? 155 ASP A HB3  1 
ATOM   2366 N N    . CYS A 1 156 ? -26.88153 14.04460  -17.13401 1.000 47.75767  ? 156 CYS A N    1 
ATOM   2367 C CA   . CYS A 1 156 ? -26.00440 14.02345  -15.97134 1.000 58.14552  ? 156 CYS A CA   1 
ATOM   2368 C C    . CYS A 1 156 ? -25.00885 12.87464  -16.08628 1.000 49.04797  ? 156 CYS A C    1 
ATOM   2369 O O    . CYS A 1 156 ? -25.40232 11.71886  -16.27489 1.000 41.61013  ? 156 CYS A O    1 
ATOM   2370 C CB   . CYS A 1 156 ? -26.82509 13.88699  -14.68917 1.000 50.58864  ? 156 CYS A CB   1 
ATOM   2371 S SG   . CYS A 1 156 ? -25.83167 13.84876  -13.19247 1.000 60.59836  ? 156 CYS A SG   1 
ATOM   2372 H H    . CYS A 1 156 ? -27.49227 13.43957  -17.11105 1.000 57.30298  ? 156 CYS A H    1 
ATOM   2373 H HA   . CYS A 1 156 ? -25.49919 14.85059  -15.93268 1.000 69.76840  ? 156 CYS A HA   1 
ATOM   2374 H HB2  . CYS A 1 156 ? -27.42930 14.64303  -14.62415 1.000 60.70014  ? 156 CYS A HB2  1 
ATOM   2375 H HB3  . CYS A 1 156 ? -27.33112 13.06043  -14.72974 1.000 60.70014  ? 156 CYS A HB3  1 
ATOM   2376 H HG   . CYS A 1 156 ? -25.06969 12.92371  -13.25284 1.000 72.71181  ? 156 CYS A HG   1 
ATOM   2377 N N    . VAL A 1 157 ? -23.72424 13.19371  -15.95524 1.000 50.12389  ? 157 VAL A N    1 
ATOM   2378 C CA   . VAL A 1 157 ? -22.64783 12.22529  -16.12724 1.000 46.53946  ? 157 VAL A CA   1 
ATOM   2379 C C    . VAL A 1 157 ? -22.25499 11.69622  -14.75586 1.000 39.17196  ? 157 VAL A C    1 
ATOM   2380 O O    . VAL A 1 157 ? -21.75185 12.44734  -13.91222 1.000 40.61453  ? 157 VAL A O    1 
ATOM   2381 C CB   . VAL A 1 157 ? -21.44084 12.85470  -16.84500 1.000 38.31354  ? 157 VAL A CB   1 
ATOM   2382 C CG1  . VAL A 1 157 ? -20.35232 11.81194  -17.07904 1.000 38.03844  ? 157 VAL A CG1  1 
ATOM   2383 C CG2  . VAL A 1 157 ? -21.87945 13.47994  -18.16072 1.000 40.45226  ? 157 VAL A CG2  1 
ATOM   2384 H H    . VAL A 1 157 ? -23.44578 13.98419  -15.76234 1.000 60.14244  ? 157 VAL A H    1 
ATOM   2385 H HA   . VAL A 1 157 ? -22.96918 11.48023  -16.65875 1.000 55.84113  ? 157 VAL A HA   1 
ATOM   2386 H HB   . VAL A 1 157 ? -21.06870 13.55360  -16.28469 1.000 45.97002  ? 157 VAL A HB   1 
ATOM   2387 H HG11 . VAL A 1 157 ? -19.64905 12.20529  -17.61904 1.000 45.63990  ? 157 VAL A HG11 1 
ATOM   2388 H HG12 . VAL A 1 157 ? -19.99399 11.53173  -16.22231 1.000 45.63990  ? 157 VAL A HG12 1 
ATOM   2389 H HG13 . VAL A 1 157 ? -20.73787 11.05119  -17.54112 1.000 45.63990  ? 157 VAL A HG13 1 
ATOM   2390 H HG21 . VAL A 1 157 ? -21.09269 13.69824  -18.68441 1.000 48.53648  ? 157 VAL A HG21 1 
ATOM   2391 H HG22 . VAL A 1 157 ? -22.43230 12.84545  -18.64309 1.000 48.53648  ? 157 VAL A HG22 1 
ATOM   2392 H HG23 . VAL A 1 157 ? -22.38651 14.28551  -17.97402 1.000 48.53648  ? 157 VAL A HG23 1 
ATOM   2393 N N    . SER A 1 158 ? -22.47427 10.40609  -14.52340 1.000 38.03766  ? 158 SER A N    1 
ATOM   2394 C CA   . SER A 1 158 ? -22.04498 9.75497   -13.28718 1.000 41.41732  ? 158 SER A CA   1 
ATOM   2395 C C    . SER A 1 158 ? -20.68485 9.10598   -13.53700 1.000 38.42014  ? 158 SER A C    1 
ATOM   2396 O O    . SER A 1 158 ? -20.59710 8.06327   -14.18893 1.000 32.50839  ? 158 SER A O    1 
ATOM   2397 C CB   . SER A 1 158 ? -23.07513 8.73107   -12.82331 1.000 38.04194  ? 158 SER A CB   1 
ATOM   2398 O OG   . SER A 1 158 ? -24.26238 9.36500   -12.37864 1.000 55.99306  ? 158 SER A OG   1 
ATOM   2399 H H    . SER A 1 158 ? -22.87475 9.87959   -15.07296 1.000 45.63896  ? 158 SER A H    1 
ATOM   2400 H HA   . SER A 1 158 ? -21.94456 10.42529  -12.59329 1.000 49.69456  ? 158 SER A HA   1 
ATOM   2401 H HB2  . SER A 1 158 ? -23.29084 8.14393   -13.56469 1.000 45.64410  ? 158 SER A HB2  1 
ATOM   2402 H HB3  . SER A 1 158 ? -22.69999 8.21699   -12.09127 1.000 45.64410  ? 158 SER A HB3  1 
ATOM   2403 H HG   . SER A 1 158 ? -24.79305 8.79400   -12.06567 1.000 67.18545  ? 158 SER A HG   1 
ATOM   2404 N N    . PHE A 1 159 ? -19.62401 9.72912   -13.02201 1.000 34.93187  ? 159 PHE A N    1 
ATOM   2405 C CA   . PHE A 1 159 ? -18.28702 9.15123   -13.10447 1.000 36.37484  ? 159 PHE A CA   1 
ATOM   2406 C C    . PHE A 1 159 ? -18.11745 8.09398   -12.02153 1.000 35.79782  ? 159 PHE A C    1 
ATOM   2407 O O    . PHE A 1 159 ? -18.34389 8.36749   -10.83916 1.000 39.49983  ? 159 PHE A O    1 
ATOM   2408 C CB   . PHE A 1 159 ? -17.21764 10.23006  -12.94429 1.000 35.99861  ? 159 PHE A CB   1 
ATOM   2409 C CG   . PHE A 1 159 ? -17.21177 11.24291  -14.04432 1.000 37.12852  ? 159 PHE A CG   1 
ATOM   2410 C CD1  . PHE A 1 159 ? -16.55628 10.98780  -15.23733 1.000 35.55204  ? 159 PHE A CD1  1 
ATOM   2411 C CD2  . PHE A 1 159 ? -17.85748 12.45379  -13.88515 1.000 36.04031  ? 159 PHE A CD2  1 
ATOM   2412 C CE1  . PHE A 1 159 ? -16.55186 11.92259  -16.24949 1.000 34.43147  ? 159 PHE A CE1  1 
ATOM   2413 C CE2  . PHE A 1 159 ? -17.85700 13.38916  -14.89270 1.000 35.17706  ? 159 PHE A CE2  1 
ATOM   2414 C CZ   . PHE A 1 159 ? -17.20287 13.12578  -16.07627 1.000 33.22965  ? 159 PHE A CZ   1 
ATOM   2415 H H    . PHE A 1 159 ? -19.65439 10.48859  -12.61965 1.000 41.91202  ? 159 PHE A H    1 
ATOM   2416 H HA   . PHE A 1 159 ? -18.17193 8.73779   -13.97437 1.000 43.64358  ? 159 PHE A HA   1 
ATOM   2417 H HB2  . PHE A 1 159 ? -17.37196 10.70035  -12.11008 1.000 43.19210  ? 159 PHE A HB2  1 
ATOM   2418 H HB3  . PHE A 1 159 ? -16.34591 9.80489   -12.92910 1.000 43.19210  ? 159 PHE A HB3  1 
ATOM   2419 H HD1  . PHE A 1 159 ? -16.11495 10.17789  -15.35638 1.000 42.65622  ? 159 PHE A HD1  1 
ATOM   2420 H HD2  . PHE A 1 159 ? -18.29769 12.63838  -13.08700 1.000 43.24214  ? 159 PHE A HD2  1 
ATOM   2421 H HE1  . PHE A 1 159 ? -16.11061 11.74243  -17.04808 1.000 41.31153  ? 159 PHE A HE1  1 
ATOM   2422 H HE2  . PHE A 1 159 ? -18.29809 14.19945  -14.77536 1.000 42.20625  ? 159 PHE A HE2  1 
ATOM   2423 H HZ   . PHE A 1 159 ? -17.20037 13.75875  -16.75763 1.000 39.86935  ? 159 PHE A HZ   1 
ATOM   2424 N N    . CYS A 1 160 ? -17.70795 6.88888   -12.42196 1.000 28.50593  ? 160 CYS A N    1 
ATOM   2425 C CA   . CYS A 1 160 ? -17.60028 5.77295   -11.49574 1.000 29.68128  ? 160 CYS A CA   1 
ATOM   2426 C C    . CYS A 1 160 ? -16.22512 5.12834   -11.44373 1.000 27.79391  ? 160 CYS A C    1 
ATOM   2427 O O    . CYS A 1 160 ? -15.97446 4.33171   -10.53173 1.000 34.57215  ? 160 CYS A O    1 
ATOM   2428 C CB   . CYS A 1 160 ? -18.62503 4.68579   -11.85429 1.000 32.55679  ? 160 CYS A CB   1 
ATOM   2429 S SG   . CYS A 1 160 ? -18.50192 4.09730   -13.56230 1.000 35.90053  ? 160 CYS A SG   1 
ATOM   2430 H H    . CYS A 1 160 ? -17.48672 6.69658   -13.23046 1.000 34.20089  ? 160 CYS A H    1 
ATOM   2431 H HA   . CYS A 1 160 ? -17.79934 6.10593   -10.60670 1.000 35.61131  ? 160 CYS A HA   1 
ATOM   2432 H HB2  . CYS A 1 160 ? -18.48899 3.92456   -11.26869 1.000 39.06192  ? 160 CYS A HB2  1 
ATOM   2433 H HB3  . CYS A 1 160 ? -19.51712 5.04548   -11.72901 1.000 39.06192  ? 160 CYS A HB3  1 
ATOM   2434 H HG   . CYS A 1 160 ? -17.41764 3.61164   -13.73100 1.000 43.07441  ? 160 CYS A HG   1 
ATOM   2435 N N    . TYR A 1 161 ? -15.33225 5.44159   -12.37672 1.000 27.65615  ? 161 TYR A N    1 
ATOM   2436 C CA   . TYR A 1 161 ? -14.08235 4.70955   -12.50273 1.000 30.21395  ? 161 TYR A CA   1 
ATOM   2437 C C    . TYR A 1 161 ? -13.00971 5.63935   -13.04415 1.000 31.30642  ? 161 TYR A C    1 
ATOM   2438 O O    . TYR A 1 161 ? -13.26092 6.42244   -13.96314 1.000 32.90206  ? 161 TYR A O    1 
ATOM   2439 C CB   . TYR A 1 161 ? -14.25629 3.48808   -13.42237 1.000 31.06275  ? 161 TYR A CB   1 
ATOM   2440 C CG   . TYR A 1 161 ? -13.00421 2.66275   -13.61520 1.000 30.31565  ? 161 TYR A CG   1 
ATOM   2441 C CD1  . TYR A 1 161 ? -12.63303 1.70157   -12.68471 1.000 35.23602  ? 161 TYR A CD1  1 
ATOM   2442 C CD2  . TYR A 1 161 ? -12.20071 2.83607   -14.73407 1.000 27.59842  ? 161 TYR A CD2  1 
ATOM   2443 C CE1  . TYR A 1 161 ? -11.49225 0.94690   -12.85462 1.000 34.28983  ? 161 TYR A CE1  1 
ATOM   2444 C CE2  . TYR A 1 161 ? -11.05822 2.08544   -14.91357 1.000 26.81320  ? 161 TYR A CE2  1 
ATOM   2445 C CZ   . TYR A 1 161 ? -10.70765 1.14121   -13.97011 1.000 32.96448  ? 161 TYR A CZ   1 
ATOM   2446 O OH   . TYR A 1 161 ? -9.57148  0.38232   -14.13457 1.000 26.52520  ? 161 TYR A OH   1 
ATOM   2447 H H    . TYR A 1 161 ? -15.42938 6.07600   -12.94916 1.000 33.18115  ? 161 TYR A H    1 
ATOM   2448 H HA   . TYR A 1 161 ? -13.78956 4.40021   -11.63125 1.000 36.25051  ? 161 TYR A HA   1 
ATOM   2449 H HB2  . TYR A 1 161 ? -14.93320 2.90788   -13.04021 1.000 37.26907  ? 161 TYR A HB2  1 
ATOM   2450 H HB3  . TYR A 1 161 ? -14.54003 3.79789   -14.29668 1.000 37.26907  ? 161 TYR A HB3  1 
ATOM   2451 H HD1  . TYR A 1 161 ? -13.16359 1.56446   -11.93332 1.000 42.27700  ? 161 TYR A HD1  1 
ATOM   2452 H HD2  . TYR A 1 161 ? -12.43705 3.46903   -15.37312 1.000 33.11188  ? 161 TYR A HD2  1 
ATOM   2453 H HE1  . TYR A 1 161 ? -11.25365 0.31033   -12.22000 1.000 41.14157  ? 161 TYR A HE1  1 
ATOM   2454 H HE2  . TYR A 1 161 ? -10.52701 2.21465   -15.66591 1.000 32.16961  ? 161 TYR A HE2  1 
ATOM   2455 H HH   . TYR A 1 161 ? -9.31925  0.41247   -14.93524 1.000 31.82401  ? 161 TYR A HH   1 
ATOM   2456 N N    . MET A 1 162 ? -11.82734 5.56944   -12.44019 1.000 32.04344  ? 162 MET A N    1 
ATOM   2457 C CA   . MET A 1 162 ? -10.61001 6.12735   -13.00965 1.000 35.06327  ? 162 MET A CA   1 
ATOM   2458 C C    . MET A 1 162 ? -9.56780  5.01735   -13.04672 1.000 35.99683  ? 162 MET A C    1 
ATOM   2459 O O    . MET A 1 162 ? -9.42710  4.25582   -12.08389 1.000 32.67982  ? 162 MET A O    1 
ATOM   2460 C CB   . MET A 1 162 ? -10.09536 7.33346   -12.21003 1.000 33.38384  ? 162 MET A CB   1 
ATOM   2461 C CG   . MET A 1 162 ? -8.78404  7.88428   -12.74994 1.000 33.58191  ? 162 MET A CG   1 
ATOM   2462 S SD   . MET A 1 162 ? -8.27145  9.47135   -12.06042 1.000 39.60836  ? 162 MET A SD   1 
ATOM   2463 C CE   . MET A 1 162 ? -8.98781  10.61817  -13.23514 1.000 29.38242  ? 162 MET A CE   1 
ATOM   2464 H H    . MET A 1 162 ? -11.70359 5.19217   -11.67733 1.000 38.44590  ? 162 MET A H    1 
ATOM   2465 H HA   . MET A 1 162 ? -10.77851 6.45304   -13.90767 1.000 42.06970  ? 162 MET A HA   1 
ATOM   2466 H HB2  . MET A 1 162 ? -10.75661 8.04214   -12.24779 1.000 40.05438  ? 162 MET A HB2  1 
ATOM   2467 H HB3  . MET A 1 162 ? -9.95093  7.06317   -11.28972 1.000 40.05438  ? 162 MET A HB3  1 
ATOM   2468 H HG2  . MET A 1 162 ? -8.08076  7.24469   -12.55704 1.000 40.29207  ? 162 MET A HG2  1 
ATOM   2469 H HG3  . MET A 1 162 ? -8.87261  8.00085   -13.70883 1.000 40.29207  ? 162 MET A HG3  1 
ATOM   2470 H HE1  . MET A 1 162 ? -9.94878  10.64386  -13.10557 1.000 35.25268  ? 162 MET A HE1  1 
ATOM   2471 H HE2  . MET A 1 162 ? -8.61034  11.49929  -13.08666 1.000 35.25268  ? 162 MET A HE2  1 
ATOM   2472 H HE3  . MET A 1 162 ? -8.78321  10.31794  -14.13453 1.000 35.25268  ? 162 MET A HE3  1 
ATOM   2473 N N    . HIS A 1 163 ? -8.85106  4.91697   -14.16432 1.000 32.55959  ? 163 HIS A N    1 
ATOM   2474 C CA   . HIS A 1 163 ? -7.95781  3.79222   -14.40528 1.000 33.61949  ? 163 HIS A CA   1 
ATOM   2475 C C    . HIS A 1 163 ? -6.57909  4.02692   -13.80056 1.000 33.37634  ? 163 HIS A C    1 
ATOM   2476 O O    . HIS A 1 163 ? -6.06110  5.14696   -13.81662 1.000 36.41516  ? 163 HIS A O    1 
ATOM   2477 C CB   . HIS A 1 163 ? -7.80713  3.53359   -15.90259 1.000 28.97303  ? 163 HIS A CB   1 
ATOM   2478 C CG   . HIS A 1 163 ? -6.90322  2.38679   -16.21413 1.000 28.19430  ? 163 HIS A CG   1 
ATOM   2479 N ND1  . HIS A 1 163 ? -7.17291  1.10125   -15.79977 1.000 30.82156  ? 163 HIS A ND1  1 
ATOM   2480 C CD2  . HIS A 1 163 ? -5.72368  2.33112   -16.87515 1.000 32.64212  ? 163 HIS A CD2  1 
ATOM   2481 C CE1  . HIS A 1 163 ? -6.20333  0.29980   -16.20182 1.000 37.94801  ? 163 HIS A CE1  1 
ATOM   2482 N NE2  . HIS A 1 163 ? -5.31332  1.02040   -16.85975 1.000 37.44014  ? 163 HIS A NE2  1 
ATOM   2483 H H    . HIS A 1 163 ? -8.86658  5.49365   -14.80213 1.000 39.06528  ? 163 HIS A H    1 
ATOM   2484 H HA   . HIS A 1 163 ? -8.34127  3.00875   -13.98099 1.000 40.33716  ? 163 HIS A HA   1 
ATOM   2485 H HB2  . HIS A 1 163 ? -8.68003  3.33546   -16.27633 1.000 34.76141  ? 163 HIS A HB2  1 
ATOM   2486 H HB3  . HIS A 1 163 ? -7.43862  4.32650   -16.32258 1.000 34.76141  ? 163 HIS A HB3  1 
ATOM   2487 H HD2  . HIS A 1 163 ? -5.27528  3.04587   -17.26626 1.000 39.16432  ? 163 HIS A HD2  1 
ATOM   2488 H HE1  . HIS A 1 163 ? -6.15542  -0.61612  -16.04786 1.000 45.53138  ? 163 HIS A HE1  1 
ATOM   2489 H HE2  . HIS A 1 163 ? -4.59343  0.71796   -17.22015 1.000 44.92195  ? 163 HIS A HE2  1 
ATOM   2490 N N    . HIS A 1 164 ? -5.97109  2.94871   -13.29904 1.000 33.88477  ? 164 HIS A N    1 
ATOM   2491 C CA   . HIS A 1 164 ? -4.67030  3.05125   -12.65083 1.000 36.32924  ? 164 HIS A CA   1 
ATOM   2492 C C    . HIS A 1 164 ? -3.64824  2.02951   -13.13934 1.000 31.71211  ? 164 HIS A C    1 
ATOM   2493 O O    . HIS A 1 164 ? -2.51137  2.40053   -13.44700 1.000 39.51711  ? 164 HIS A O    1 
ATOM   2494 C CB   . HIS A 1 164 ? -4.83219  2.90972   -11.13588 1.000 30.78869  ? 164 HIS A CB   1 
ATOM   2495 C CG   . HIS A 1 164 ? -5.42481  4.11492   -10.47760 1.000 33.63895  ? 164 HIS A CG   1 
ATOM   2496 N ND1  . HIS A 1 164 ? -4.70323  4.93380   -9.63583  1.000 31.65829  ? 164 HIS A ND1  1 
ATOM   2497 C CD2  . HIS A 1 164 ? -6.66864  4.64525   -10.54322 1.000 30.66070  ? 164 HIS A CD2  1 
ATOM   2498 C CE1  . HIS A 1 164 ? -5.47925  5.91262   -9.20569  1.000 33.12785  ? 164 HIS A CE1  1 
ATOM   2499 N NE2  . HIS A 1 164 ? -6.67630  5.76176   -9.74313  1.000 36.55921  ? 164 HIS A NE2  1 
ATOM   2500 H H    . HIS A 1 164 ? -6.29309  2.15164   -13.32344 1.000 40.65549  ? 164 HIS A H    1 
ATOM   2501 H HA   . HIS A 1 164 ? -4.31504  3.92498   -12.87730 1.000 43.58887  ? 164 HIS A HA   1 
ATOM   2502 H HB2  . HIS A 1 164 ? -5.41519  2.15620   -10.95364 1.000 36.94020  ? 164 HIS A HB2  1 
ATOM   2503 H HB3  . HIS A 1 164 ? -3.95911  2.75656   -10.74195 1.000 36.94020  ? 164 HIS A HB3  1 
ATOM   2504 H HD1  . HIS A 1 164 ? -3.87697  4.82462   -9.42378  1.000 37.98372  ? 164 HIS A HD1  1 
ATOM   2505 H HD2  . HIS A 1 164 ? -7.38404  4.31538   -11.03748 1.000 36.78661  ? 164 HIS A HD2  1 
ATOM   2506 H HE1  . HIS A 1 164 ? -5.22582  6.59219   -8.62358  1.000 39.74719  ? 164 HIS A HE1  1 
ATOM   2507 N N    . MET A 1 165 ? -4.01740  0.75029   -13.20979 1.000 35.72307  ? 165 MET A N    1 
ATOM   2508 C CA   . MET A 1 165 ? -3.01864  -0.29626  -13.38228 1.000 40.98106  ? 165 MET A CA   1 
ATOM   2509 C C    . MET A 1 165 ? -3.61385  -1.52255  -14.06061 1.000 35.93989  ? 165 MET A C    1 
ATOM   2510 O O    . MET A 1 165 ? -4.83161  -1.66639  -14.19323 1.000 32.82288  ? 165 MET A O    1 
ATOM   2511 C CB   . MET A 1 165 ? -2.42106  -0.70044  -12.02912 1.000 40.09550  ? 165 MET A CB   1 
ATOM   2512 C CG   . MET A 1 165 ? -3.47806  -1.13826  -11.01392 1.000 37.33242  ? 165 MET A CG   1 
ATOM   2513 S SD   . MET A 1 165 ? -2.86710  -1.23041  -9.31956  1.000 45.48501  ? 165 MET A SD   1 
ATOM   2514 C CE   . MET A 1 165 ? -2.82966  -3.00401  -9.04961  1.000 53.84845  ? 165 MET A CE   1 
ATOM   2515 H H    . MET A 1 165 ? -4.82901  0.47013   -13.16070 1.000 42.86145  ? 165 MET A H    1 
ATOM   2516 H HA   . MET A 1 165 ? -2.32806  0.05964   -13.96308 1.000 49.17104  ? 165 MET A HA   1 
ATOM   2517 H HB2  . MET A 1 165 ? -1.81055  -1.44206  -12.16389 1.000 48.10838  ? 165 MET A HB2  1 
ATOM   2518 H HB3  . MET A 1 165 ? -1.94466  0.05797   -11.65662 1.000 48.10838  ? 165 MET A HB3  1 
ATOM   2519 H HG2  . MET A 1 165 ? -4.20901  -0.50080  -11.03009 1.000 44.79267  ? 165 MET A HG2  1 
ATOM   2520 H HG3  . MET A 1 165 ? -3.80074  -2.01932  -11.25989 1.000 44.79267  ? 165 MET A HG3  1 
ATOM   2521 H HE1  . MET A 1 165 ? -3.32275  -3.44217  -9.76079  1.000 64.61192  ? 165 MET A HE1  1 
ATOM   2522 H HE2  . MET A 1 165 ? -1.90740  -3.30453  -9.05274  1.000 64.61192  ? 165 MET A HE2  1 
ATOM   2523 H HE3  . MET A 1 165 ? -3.23908  -3.20175  -8.19277  1.000 64.61192  ? 165 MET A HE3  1 
ATOM   2524 N N    . GLU A 1 166 ? -2.72070  -2.42135  -14.47118 1.000 38.09014  ? 166 GLU A N    1 
ATOM   2525 C CA   . GLU A 1 166 ? -3.07718  -3.69616  -15.07926 1.000 43.71530  ? 166 GLU A CA   1 
ATOM   2526 C C    . GLU A 1 166 ? -2.57053  -4.83060  -14.19908 1.000 40.32468  ? 166 GLU A C    1 
ATOM   2527 O O    . GLU A 1 166 ? -1.42091  -4.80575  -13.74906 1.000 44.08751  ? 166 GLU A O    1 
ATOM   2528 C CB   . GLU A 1 166 ? -2.48646  -3.80950  -16.48647 1.000 40.10854  ? 166 GLU A CB   1 
ATOM   2529 C CG   . GLU A 1 166 ? -2.64728  -5.17892  -17.12154 1.000 37.20979  ? 166 GLU A CG   1 
ATOM   2530 C CD   . GLU A 1 166 ? -2.11657  -5.22196  -18.53775 1.000 45.38737  ? 166 GLU A CD   1 
ATOM   2531 O OE1  . GLU A 1 166 ? -2.45205  -4.31231  -19.32844 1.000 43.70825  ? 166 GLU A OE1  1 
ATOM   2532 O OE2  . GLU A 1 166 ? -1.35836  -6.16129  -18.85972 1.000 51.85034  ? 166 GLU A OE2  1 
ATOM   2533 H H    . GLU A 1 166 ? -1.87079  -2.30833  -14.40430 1.000 45.70194  ? 166 GLU A H    1 
ATOM   2534 H HA   . GLU A 1 166 ? -4.04211  -3.77103  -15.14403 1.000 52.45213  ? 166 GLU A HA   1 
ATOM   2535 H HB2  . GLU A 1 166 ? -2.92867  -3.16512  -17.06103 1.000 48.12401  ? 166 GLU A HB2  1 
ATOM   2536 H HB3  . GLU A 1 166 ? -1.53700  -3.61634  -16.44049 1.000 48.12401  ? 166 GLU A HB3  1 
ATOM   2537 H HG2  . GLU A 1 166 ? -2.15889  -5.83202  -16.59634 1.000 44.64552  ? 166 GLU A HG2  1 
ATOM   2538 H HG3  . GLU A 1 166 ? -3.58917  -5.40953  -17.14517 1.000 44.64552  ? 166 GLU A HG3  1 
ATOM   2539 N N    . LEU A 1 167 ? -3.42019  -5.81716  -13.96429 1.000 38.31241  ? 167 LEU A N    1 
ATOM   2540 C CA   . LEU A 1 167 ? -3.11601  -6.97173  -13.13400 1.000 47.43126  ? 167 LEU A CA   1 
ATOM   2541 C C    . LEU A 1 167 ? -2.73144  -8.16945  -13.98842 1.000 57.06434  ? 167 LEU A C    1 
ATOM   2542 O O    . LEU A 1 167 ? -2.89910  -8.16584  -15.21168 1.000 57.77508  ? 167 LEU A O    1 
ATOM   2543 C CB   . LEU A 1 167 ? -4.32509  -7.32220  -12.26620 1.000 48.01342  ? 167 LEU A CB   1 
ATOM   2544 C CG   . LEU A 1 167 ? -4.59868  -6.42024  -11.06449 1.000 47.63310  ? 167 LEU A CG   1 
ATOM   2545 C CD1  . LEU A 1 167 ? -6.02570  -6.62210  -10.57221 1.000 45.30635  ? 167 LEU A CD1  1 
ATOM   2546 C CD2  . LEU A 1 167 ? -3.60419  -6.69189  -9.94835  1.000 51.01623  ? 167 LEU A CD2  1 
ATOM   2547 H H    . LEU A 1 167 ? -4.21573  -5.84111  -14.29008 1.000 45.96866  ? 167 LEU A H    1 
ATOM   2548 H HA   . LEU A 1 167 ? -2.36776  -6.75595  -12.55568 1.000 56.91128  ? 167 LEU A HA   1 
ATOM   2549 H HB2  . LEU A 1 167 ? -5.11501  -7.29232  -12.82837 1.000 57.60988  ? 167 LEU A HB2  1 
ATOM   2550 H HB3  . LEU A 1 167 ? -4.19609  -8.22015  -11.92277 1.000 57.60988  ? 167 LEU A HB3  1 
ATOM   2551 H HG   . LEU A 1 167 ? -4.49511  -5.49386  -11.33280 1.000 57.15349  ? 167 LEU A HG   1 
ATOM   2552 H HD11 . LEU A 1 167 ? -6.19842  -6.00594  -9.84322  1.000 54.36139  ? 167 LEU A HD11 1 
ATOM   2553 H HD12 . LEU A 1 167 ? -6.63935  -6.44976  -11.30340 1.000 54.36139  ? 167 LEU A HD12 1 
ATOM   2554 H HD13 . LEU A 1 167 ? -6.12705  -7.53615  -10.26378 1.000 54.36139  ? 167 LEU A HD13 1 
ATOM   2555 H HD21 . LEU A 1 167 ? -3.67670  -5.98982  -9.28297  1.000 61.21324  ? 167 LEU A HD21 1 
ATOM   2556 H HD22 . LEU A 1 167 ? -3.80755  -7.55092  -9.54633  1.000 61.21324  ? 167 LEU A HD22 1 
ATOM   2557 H HD23 . LEU A 1 167 ? -2.70822  -6.70432  -10.31980 1.000 61.21324  ? 167 LEU A HD23 1 
ATOM   2558 N N    . PRO A 1 168 ? -2.20040  -9.22571  -13.36782 1.000 62.89007  ? 168 PRO A N    1 
ATOM   2559 C CA   . PRO A 1 168 ? -1.92937  -10.46034 -14.11281 1.000 58.75163  ? 168 PRO A CA   1 
ATOM   2560 C C    . PRO A 1 168 ? -3.14006  -10.92375 -14.91000 1.000 57.16664  ? 168 PRO A C    1 
ATOM   2561 O O    . PRO A 1 168 ? -4.28765  -10.76179 -14.49092 1.000 60.95484  ? 168 PRO A O    1 
ATOM   2562 C CB   . PRO A 1 168 ? -1.56899  -11.46337 -13.01155 1.000 62.37875  ? 168 PRO A CB   1 
ATOM   2563 C CG   . PRO A 1 168 ? -0.96658  -10.62142 -11.93252 1.000 67.18027  ? 168 PRO A CG   1 
ATOM   2564 C CD   . PRO A 1 168 ? -1.66031  -9.27827  -11.99448 1.000 59.71578  ? 168 PRO A CD   1 
ATOM   2565 H HA   . PRO A 1 168 ? -1.17778  -10.33484 -14.71302 1.000 70.49573  ? 168 PRO A HA   1 
ATOM   2566 H HB2  . PRO A 1 168 ? -2.36774  -11.91565 -12.69797 1.000 74.84827  ? 168 PRO A HB2  1 
ATOM   2567 H HB3  . PRO A 1 168 ? -0.93057  -12.11199 -13.34712 1.000 74.84827  ? 168 PRO A HB3  1 
ATOM   2568 H HG2  . PRO A 1 168 ? -1.11560  -11.04258 -11.07152 1.000 80.61009  ? 168 PRO A HG2  1 
ATOM   2569 H HG3  . PRO A 1 168 ? -0.01514  -10.52130 -12.09263 1.000 80.61009  ? 168 PRO A HG3  1 
ATOM   2570 H HD2  . PRO A 1 168 ? -2.37624  -9.23092  -11.34171 1.000 71.65271  ? 168 PRO A HD2  1 
ATOM   2571 H HD3  . PRO A 1 168 ? -1.02796  -8.55782  -11.84618 1.000 71.65271  ? 168 PRO A HD3  1 
ATOM   2572 N N    . THR A 1 169 ? -2.86416  -11.52141 -16.06749 1.000 60.80399  ? 169 THR A N    1 
ATOM   2573 C CA   . THR A 1 169 ? -3.84922  -12.03428 -17.01698 1.000 54.40176  ? 169 THR A CA   1 
ATOM   2574 C C    . THR A 1 169 ? -4.46754  -10.91259 -17.84177 1.000 55.76354  ? 169 THR A C    1 
ATOM   2575 O O    . THR A 1 169 ? -5.44075  -11.15772 -18.57332 1.000 57.32950  ? 169 THR A O    1 
ATOM   2576 C CB   . THR A 1 169 ? -4.96725  -12.82841 -16.33183 1.000 68.74765  ? 169 THR A CB   1 
ATOM   2577 O OG1  . THR A 1 169 ? -5.87213  -11.93002 -15.67627 1.000 69.28231  ? 169 THR A OG1  1 
ATOM   2578 C CG2  . THR A 1 169 ? -4.38012  -13.79521 -15.30804 1.000 58.84234  ? 169 THR A CG2  1 
ATOM   2579 H H    . THR A 1 169 ? -2.05852  -11.64844 -16.34026 1.000 72.95857  ? 169 THR A H    1 
ATOM   2580 H HA   . THR A 1 169 ? -3.39662  -12.63762 -17.62693 1.000 65.27588  ? 169 THR A HA   1 
ATOM   2581 H HB   . THR A 1 169 ? -5.45376  -13.34070 -16.99649 1.000 82.49095  ? 169 THR A HB   1 
ATOM   2582 H HG1  . THR A 1 169 ? -6.60405  -12.31541 -15.53007 1.000 83.13254  ? 169 THR A HG1  1 
ATOM   2583 H HG21 . THR A 1 169 ? -4.94887  -14.57661 -15.22539 1.000 70.60458  ? 169 THR A HG21 1 
ATOM   2584 H HG22 . THR A 1 169 ? -3.49548  -14.07794 -15.58798 1.000 70.60458  ? 169 THR A HG22 1 
ATOM   2585 H HG23 . THR A 1 169 ? -4.31300  -13.36178 -14.44286 1.000 70.60458  ? 169 THR A HG23 1 
ATOM   2586 N N    . GLY A 1 170 ? -3.94284  -9.69350  -17.75435 1.000 47.15918  ? 170 GLY A N    1 
ATOM   2587 C CA   . GLY A 1 170 ? -4.42083  -8.62029  -18.60108 1.000 51.78522  ? 170 GLY A CA   1 
ATOM   2588 C C    . GLY A 1 170 ? -5.74995  -8.02332  -18.20078 1.000 55.80387  ? 170 GLY A C    1 
ATOM   2589 O O    . GLY A 1 170 ? -6.46763  -7.50477  -19.06146 1.000 50.64549  ? 170 GLY A O    1 
ATOM   2590 H H    . GLY A 1 170 ? -3.31269  -9.46826  -17.21419 1.000 56.58479  ? 170 GLY A H    1 
ATOM   2591 H HA2  . GLY A 1 170 ? -3.76440  -7.90618  -18.59455 1.000 62.13603  ? 170 GLY A HA2  1 
ATOM   2592 H HA3  . GLY A 1 170 ? -4.51125  -8.95786  -19.50594 1.000 62.13603  ? 170 GLY A HA3  1 
ATOM   2593 N N    . VAL A 1 171 ? -6.10738  -8.08728  -16.92386 1.000 50.18472  ? 171 VAL A N    1 
ATOM   2594 C CA   . VAL A 1 171 ? -7.28403  -7.40825  -16.41526 1.000 44.44431  ? 171 VAL A CA   1 
ATOM   2595 C C    . VAL A 1 171 ? -6.83081  -6.09556  -15.78723 1.000 39.02257  ? 171 VAL A C    1 
ATOM   2596 O O    . VAL A 1 171 ? -5.64009  -5.81630  -15.67340 1.000 37.65943  ? 171 VAL A O    1 
ATOM   2597 C CB   . VAL A 1 171 ? -8.07685  -8.28248  -15.41066 1.000 54.26335  ? 171 VAL A CB   1 
ATOM   2598 C CG1  . VAL A 1 171 ? -8.50422  -9.58285  -16.07146 1.000 56.49890  ? 171 VAL A CG1  1 
ATOM   2599 C CG2  . VAL A 1 171 ? -7.25724  -8.55314  -14.15420 1.000 53.61042  ? 171 VAL A CG2  1 
ATOM   2600 H H    . VAL A 1 171 ? -5.67463  -8.52639  -16.32427 1.000 60.21543  ? 171 VAL A H    1 
ATOM   2601 H HA   . VAL A 1 171 ? -7.88295  -7.21157  -17.15249 1.000 53.32694  ? 171 VAL A HA   1 
ATOM   2602 H HB   . VAL A 1 171 ? -8.87424  -7.80173  -15.13873 1.000 65.10980  ? 171 VAL A HB   1 
ATOM   2603 H HG11 . VAL A 1 171 ? -8.90896  -10.15830 -15.40367 1.000 67.79245  ? 171 VAL A HG11 1 
ATOM   2604 H HG12 . VAL A 1 171 ? -9.14648  -9.38540  -16.77104 1.000 67.79245  ? 171 VAL A HG12 1 
ATOM   2605 H HG13 . VAL A 1 171 ? -7.72362  -10.01538 -16.45154 1.000 67.79245  ? 171 VAL A HG13 1 
ATOM   2606 H HG21 . VAL A 1 171 ? -6.34861  -8.77468  -14.41150 1.000 64.32627  ? 171 VAL A HG21 1 
ATOM   2607 H HG22 . VAL A 1 171 ? -7.25917  -7.75807  -13.59854 1.000 64.32627  ? 171 VAL A HG22 1 
ATOM   2608 H HG23 . VAL A 1 171 ? -7.65457  -9.29489  -13.67166 1.000 64.32627  ? 171 VAL A HG23 1 
ATOM   2609 N N    . HIS A 1 172 ? -7.78630  -5.27193  -15.37172 1.000 41.34815  ? 172 HIS A N    1 
ATOM   2610 C CA   . HIS A 1 172 ? -7.48038  -3.89355  -15.02100 1.000 36.53484  ? 172 HIS A CA   1 
ATOM   2611 C C    . HIS A 1 172 ? -8.15503  -3.49908  -13.71900 1.000 31.77237  ? 172 HIS A C    1 
ATOM   2612 O O    . HIS A 1 172 ? -9.20775  -4.02696  -13.35458 1.000 36.68017  ? 172 HIS A O    1 
ATOM   2613 C CB   . HIS A 1 172 ? -7.88739  -2.95825  -16.16295 1.000 35.68449  ? 172 HIS A CB   1 
ATOM   2614 C CG   . HIS A 1 172 ? -7.15167  -3.23199  -17.43716 1.000 39.20282  ? 172 HIS A CG   1 
ATOM   2615 N ND1  . HIS A 1 172 ? -7.72449  -3.89247  -18.50274 1.000 37.53662  ? 172 HIS A ND1  1 
ATOM   2616 C CD2  . HIS A 1 172 ? -5.87418  -2.96759  -17.80075 1.000 40.04263  ? 172 HIS A CD2  1 
ATOM   2617 C CE1  . HIS A 1 172 ? -6.83834  -4.00223  -19.47679 1.000 41.31519  ? 172 HIS A CE1  1 
ATOM   2618 N NE2  . HIS A 1 172 ? -5.70782  -3.44813  -19.07675 1.000 37.61109  ? 172 HIS A NE2  1 
ATOM   2619 H H    . HIS A 1 172 ? -8.61409  -5.48867  -15.28580 1.000 49.61155  ? 172 HIS A H    1 
ATOM   2620 H HA   . HIS A 1 172 ? -6.52864  -3.79450  -14.86199 1.000 43.83557  ? 172 HIS A HA   1 
ATOM   2621 H HB2  . HIS A 1 172 ? -8.83555  -3.06750  -16.33600 1.000 42.81516  ? 172 HIS A HB2  1 
ATOM   2622 H HB3  . HIS A 1 172 ? -7.70123  -2.04298  -15.90117 1.000 42.81516  ? 172 HIS A HB3  1 
ATOM   2623 H HD2  . HIS A 1 172 ? -5.23009  -2.54059  -17.28334 1.000 48.04492  ? 172 HIS A HD2  1 
ATOM   2624 H HE1  . HIS A 1 172 ? -6.98555  -4.40175  -20.30360 1.000 49.57200  ? 172 HIS A HE1  1 
ATOM   2625 H HE2  . HIS A 1 172 ? -4.98507  -3.39663  -19.53998 1.000 45.12708  ? 172 HIS A HE2  1 
ATOM   2626 N N    . ALA A 1 173 ? -7.52024  -2.56349  -13.01660 1.000 31.98466  ? 173 ALA A N    1 
ATOM   2627 C CA   . ALA A 1 173 ? -7.96477  -2.13317  -11.70236 1.000 30.18776  ? 173 ALA A CA   1 
ATOM   2628 C C    . ALA A 1 173 ? -7.83887  -0.62221  -11.60152 1.000 30.76011  ? 173 ALA A C    1 
ATOM   2629 O O    . ALA A 1 173 ? -6.93490  -0.01490  -12.18023 1.000 36.15969  ? 173 ALA A O    1 
ATOM   2630 C CB   . ALA A 1 173 ? -7.15379  -2.80769  -10.58581 1.000 33.67967  ? 173 ALA A CB   1 
ATOM   2631 H H    . ALA A 1 173 ? -6.81375  -2.15618  -13.28968 1.000 38.37536  ? 173 ALA A H    1 
ATOM   2632 H HA   . ALA A 1 173 ? -8.89846  -2.36592  -11.58006 1.000 36.21908  ? 173 ALA A HA   1 
ATOM   2633 H HB1  . ALA A 1 173 ? -7.43126  -2.44433  -9.73032  1.000 40.40938  ? 173 ALA A HB1  1 
ATOM   2634 H HB2  . ALA A 1 173 ? -7.31903  -3.76324  -10.60861 1.000 40.40938  ? 173 ALA A HB2  1 
ATOM   2635 H HB3  . ALA A 1 173 ? -6.21085  -2.63154  -10.72984 1.000 40.40938  ? 173 ALA A HB3  1 
ATOM   2636 N N    . GLY A 1 174 ? -8.75661  -0.02741  -10.86391 1.000 30.84883  ? 174 GLY A N    1 
ATOM   2637 C CA   . GLY A 1 174 ? -8.74806  1.39787   -10.66036 1.000 28.06575  ? 174 GLY A CA   1 
ATOM   2638 C C    . GLY A 1 174 ? -9.62577  1.79165   -9.50089  1.000 35.89719  ? 174 GLY A C    1 
ATOM   2639 O O    . GLY A 1 174 ? -9.99931  0.96499   -8.66648  1.000 26.08106  ? 174 GLY A O    1 
ATOM   2640 H H    . GLY A 1 174 ? -9.40136  -0.43543  -10.46716 1.000 37.01237  ? 174 GLY A H    1 
ATOM   2641 H HA2  . GLY A 1 174 ? -7.84279  1.69511   -10.47862 1.000 33.67268  ? 174 GLY A HA2  1 
ATOM   2642 H HA3  . GLY A 1 174 ? -9.07206  1.84253   -11.45924 1.000 33.67268  ? 174 GLY A HA3  1 
ATOM   2643 N N    . THR A 1 175 ? -9.97122  3.07370   -9.47253  1.000 31.00680  ? 175 THR A N    1 
ATOM   2644 C CA   . THR A 1 175 ? -10.60167 3.68674   -8.31925  1.000 36.48082  ? 175 THR A CA   1 
ATOM   2645 C C    . THR A 1 175 ? -11.90790 4.35325   -8.72395  1.000 34.14557  ? 175 THR A C    1 
ATOM   2646 O O    . THR A 1 175 ? -12.14359 4.65444   -9.89818  1.000 30.30708  ? 175 THR A O    1 
ATOM   2647 C CB   . THR A 1 175 ? -9.67691  4.73887   -7.67977  1.000 35.42218  ? 175 THR A CB   1 
ATOM   2648 O OG1  . THR A 1 175 ? -9.51982  5.84296   -8.58104  1.000 34.27652  ? 175 THR A OG1  1 
ATOM   2649 C CG2  . THR A 1 175 ? -8.30538  4.15553   -7.37732  1.000 32.68971  ? 175 THR A CG2  1 
ATOM   2650 H H    . THR A 1 175 ? -9.84619  3.61833   -10.12624 1.000 37.20194  ? 175 THR A H    1 
ATOM   2651 H HA   . THR A 1 175 ? -10.80481 2.99677   -7.66841  1.000 43.77076  ? 175 THR A HA   1 
ATOM   2652 H HB   . THR A 1 175 ? -10.06977 5.03919   -6.84528  1.000 42.50039  ? 175 THR A HB   1 
ATOM   2653 H HG1  . THR A 1 175 ? -9.21759  5.57257   -9.31667  1.000 41.12560  ? 175 THR A HG1  1 
ATOM   2654 H HG21 . THR A 1 175 ? -8.38405  3.44630   -6.72027  1.000 39.22142  ? 175 THR A HG21 1 
ATOM   2655 H HG22 . THR A 1 175 ? -7.91335  3.79255   -8.18692  1.000 39.22142  ? 175 THR A HG22 1 
ATOM   2656 H HG23 . THR A 1 175 ? -7.72115  4.84598   -7.02681  1.000 39.22142  ? 175 THR A HG23 1 
ATOM   2657 N N    . ASP A 1 176 ? -12.76180 4.57759   -7.72801  1.000 36.64374  ? 176 ASP A N    1 
ATOM   2658 C CA   . ASP A 1 176 ? -13.80904 5.57316   -7.87779  1.000 37.21627  ? 176 ASP A CA   1 
ATOM   2659 C C    . ASP A 1 176 ? -13.14829 6.94984   -7.93362  1.000 31.88521  ? 176 ASP A C    1 
ATOM   2660 O O    . ASP A 1 176 ? -11.92608 7.08687   -7.81078  1.000 30.43739  ? 176 ASP A O    1 
ATOM   2661 C CB   . ASP A 1 176 ? -14.83836 5.45152   -6.75125  1.000 36.68746  ? 176 ASP A CB   1 
ATOM   2662 C CG   . ASP A 1 176 ? -14.24553 5.66951   -5.36394  1.000 40.76588  ? 176 ASP A CG   1 
ATOM   2663 O OD1  . ASP A 1 176 ? -13.21518 6.36544   -5.23662  1.000 38.46940  ? 176 ASP A OD1  1 
ATOM   2664 O OD2  . ASP A 1 176 ? -14.81867 5.13217   -4.39116  1.000 38.40773  ? 176 ASP A OD2  1 
ATOM   2665 H H    . ASP A 1 176 ? -12.75302 4.17160   -6.96993  1.000 43.96626  ? 176 ASP A H    1 
ATOM   2666 H HA   . ASP A 1 176 ? -14.30087 5.43221   -8.70188  1.000 44.65329  ? 176 ASP A HA   1 
ATOM   2667 H HB2  . ASP A 1 176 ? -15.53129 6.11673   -6.88630  1.000 44.01872  ? 176 ASP A HB2  1 
ATOM   2668 H HB3  . ASP A 1 176 ? -15.22388 4.56170   -6.77332  1.000 44.01872  ? 176 ASP A HB3  1 
ATOM   2669 N N    . LEU A 1 177 ? -13.95772 7.98423   -8.14008  1.000 33.27490  ? 177 LEU A N    1 
ATOM   2670 C CA   . LEU A 1 177 ? -13.42347 9.33248   -8.28011  1.000 33.17097  ? 177 LEU A CA   1 
ATOM   2671 C C    . LEU A 1 177 ? -13.04951 9.96393   -6.94612  1.000 44.26528  ? 177 LEU A C    1 
ATOM   2672 O O    . LEU A 1 177 ? -12.64844 11.13302  -6.92523  1.000 44.03792  ? 177 LEU A O    1 
ATOM   2673 C CB   . LEU A 1 177 ? -14.42578 10.22118  -9.01871  1.000 38.44659  ? 177 LEU A CB   1 
ATOM   2674 C CG   . LEU A 1 177 ? -14.25929 10.26964  -10.53923 1.000 42.54449  ? 177 LEU A CG   1 
ATOM   2675 C CD1  . LEU A 1 177 ? -12.99622 11.04105  -10.89745 1.000 39.61039  ? 177 LEU A CD1  1 
ATOM   2676 C CD2  . LEU A 1 177 ? -14.23101 8.86252   -11.14264 1.000 35.37156  ? 177 LEU A CD2  1 
ATOM   2677 H H    . LEU A 1 177 ? -14.81377 7.93033   -8.20227  1.000 39.92365  ? 177 LEU A H    1 
ATOM   2678 H HA   . LEU A 1 177 ? -12.61766 9.29177   -8.81856  1.000 39.79894  ? 177 LEU A HA   1 
ATOM   2679 H HB2  . LEU A 1 177 ? -15.31936 9.89164   -8.83483  1.000 46.12968  ? 177 LEU A HB2  1 
ATOM   2680 H HB3  . LEU A 1 177 ? -14.33187 11.12797  -8.68731  1.000 46.12968  ? 177 LEU A HB3  1 
ATOM   2681 H HG   . LEU A 1 177 ? -15.02147 10.72846  -10.92585 1.000 51.04716  ? 177 LEU A HG   1 
ATOM   2682 H HD11 . LEU A 1 177 ? -13.09399 11.96057  -10.60450 1.000 47.52624  ? 177 LEU A HD11 1 
ATOM   2683 H HD12 . LEU A 1 177 ? -12.23855 10.63074  -10.45194 1.000 47.52624  ? 177 LEU A HD12 1 
ATOM   2684 H HD13 . LEU A 1 177 ? -12.87027 11.01178  -11.85880 1.000 47.52624  ? 177 LEU A HD13 1 
ATOM   2685 H HD21 . LEU A 1 177 ? -14.14238 8.93372   -12.10595 1.000 42.43964  ? 177 LEU A HD21 1 
ATOM   2686 H HD22 . LEU A 1 177 ? -13.47569 8.37679   -10.77597 1.000 42.43964  ? 177 LEU A HD22 1 
ATOM   2687 H HD23 . LEU A 1 177 ? -15.05748 8.40647   -10.91932 1.000 42.43964  ? 177 LEU A HD23 1 
ATOM   2688 N N    . GLU A 1 178 ? -13.17055 9.23108   -5.84124  1.000 36.33917  ? 178 GLU A N    1 
ATOM   2689 C CA   . GLU A 1 178 ? -12.60216 9.64914   -4.56766  1.000 49.07272  ? 178 GLU A CA   1 
ATOM   2690 C C    . GLU A 1 178 ? -11.27380 8.96246   -4.27226  1.000 45.00372  ? 178 GLU A C    1 
ATOM   2691 O O    . GLU A 1 178 ? -10.71638 9.16104   -3.18814  1.000 40.89081  ? 178 GLU A O    1 
ATOM   2692 C CB   . GLU A 1 178 ? -13.59052 9.38204   -3.42734  1.000 45.35164  ? 178 GLU A CB   1 
ATOM   2693 C CG   . GLU A 1 178 ? -14.81480 10.27888  -3.45138  1.000 50.36166  ? 178 GLU A CG   1 
ATOM   2694 C CD   . GLU A 1 178 ? -15.74355 10.02590  -2.27977  1.000 61.46113  ? 178 GLU A CD   1 
ATOM   2695 O OE1  . GLU A 1 178 ? -15.66476 8.93240   -1.67954  1.000 57.23095  ? 178 GLU A OE1  1 
ATOM   2696 O OE2  . GLU A 1 178 ? -16.54937 10.92363  -1.95629  1.000 70.21578  ? 178 GLU A OE2  1 
ATOM   2697 H H    . GLU A 1 178 ? -13.58377 8.47766   -5.80635  1.000 43.60078  ? 178 GLU A H    1 
ATOM   2698 H HA   . GLU A 1 178 ? -12.44627 10.60613  -4.59529  1.000 58.88103  ? 178 GLU A HA   1 
ATOM   2699 H HB2  . GLU A 1 178 ? -13.89593 8.46345   -3.48904  1.000 54.41574  ? 178 GLU A HB2  1 
ATOM   2700 H HB3  . GLU A 1 178 ? -13.13639 9.52461   -2.58215  1.000 54.41574  ? 178 GLU A HB3  1 
ATOM   2701 H HG2  . GLU A 1 178 ? -14.52979 11.20534  -3.41481  1.000 60.42776  ? 178 GLU A HG2  1 
ATOM   2702 H HG3  . GLU A 1 178 ? -15.31074 10.11637  -4.26901  1.000 60.42776  ? 178 GLU A HG3  1 
ATOM   2703 N N    . GLY A 1 179 ? -10.75839 8.16394   -5.20653  1.000 38.63597  ? 179 GLY A N    1 
ATOM   2704 C CA   . GLY A 1 179 ? -9.45838  7.54032   -5.06713  1.000 39.49325  ? 179 GLY A CA   1 
ATOM   2705 C C    . GLY A 1 179 ? -9.43625  6.22179   -4.32870  1.000 36.94231  ? 179 GLY A C    1 
ATOM   2706 O O    . GLY A 1 179 ? -8.34533  5.70533   -4.05383  1.000 36.40390  ? 179 GLY A O    1 
ATOM   2707 H H    . GLY A 1 179 ? -11.15587 7.96779   -5.94350  1.000 46.35694  ? 179 GLY A H    1 
ATOM   2708 H HA2  . GLY A 1 179 ? -9.09647  7.38434   -5.95346  1.000 47.38567  ? 179 GLY A HA2  1 
ATOM   2709 H HA3  . GLY A 1 179 ? -8.87471  8.15126   -4.59070  1.000 47.38567  ? 179 GLY A HA3  1 
ATOM   2710 N N    . ASN A 1 180 ? -10.59589 5.65708   -4.00541  1.000 37.75533  ? 180 ASN A N    1 
ATOM   2711 C CA   . ASN A 1 180 ? -10.67207 4.38181   -3.30677  1.000 35.91902  ? 180 ASN A CA   1 
ATOM   2712 C C    . ASN A 1 180 ? -10.77010 3.25254   -4.32325  1.000 36.09611  ? 180 ASN A C    1 
ATOM   2713 O O    . ASN A 1 180 ? -11.63024 3.27479   -5.20960  1.000 34.45722  ? 180 ASN A O    1 
ATOM   2714 C CB   . ASN A 1 180 ? -11.86917 4.36134   -2.35662  1.000 43.38714  ? 180 ASN A CB   1 
ATOM   2715 C CG   . ASN A 1 180 ? -11.77844 5.43562   -1.28965  1.000 42.79214  ? 180 ASN A CG   1 
ATOM   2716 O OD1  . ASN A 1 180 ? -10.96537 5.34007   -0.37232  1.000 40.93314  ? 180 ASN A OD1  1 
ATOM   2717 N ND2  . ASN A 1 180 ? -12.60786 6.46864   -1.40863  1.000 49.29368  ? 180 ASN A ND2  1 
ATOM   2718 H H    . ASN A 1 180 ? -11.36419 5.99999   -4.18352  1.000 45.30017  ? 180 ASN A H    1 
ATOM   2719 H HA   . ASN A 1 180 ? -9.87019  4.24658   -2.77800  1.000 43.09659  ? 180 ASN A HA   1 
ATOM   2720 H HB2  . ASN A 1 180 ? -12.68126 4.51001   -2.86583  1.000 52.05834  ? 180 ASN A HB2  1 
ATOM   2721 H HB3  . ASN A 1 180 ? -11.90837 3.49920   -1.91383  1.000 52.05834  ? 180 ASN A HB3  1 
ATOM   2722 H HD21 . ASN A 1 180 ? -12.59221 7.10188   -0.82694  1.000 59.14618  ? 180 ASN A HD21 1 
ATOM   2723 H HD22 . ASN A 1 180 ? -13.15979 6.50330   -2.06725  1.000 59.14618  ? 180 ASN A HD22 1 
ATOM   2724 N N    . PHE A 1 181 ? -9.88066  2.27494   -4.19680  1.000 37.25689  ? 181 PHE A N    1 
ATOM   2725 C CA   . PHE A 1 181 ? -9.80931  1.20564   -5.17842  1.000 38.67077  ? 181 PHE A CA   1 
ATOM   2726 C C    . PHE A 1 181 ? -11.05315 0.33183   -5.13447  1.000 37.14017  ? 181 PHE A C    1 
ATOM   2727 O O    . PHE A 1 181 ? -11.60421 0.05447   -4.06571  1.000 37.98395  ? 181 PHE A O    1 
ATOM   2728 C CB   . PHE A 1 181 ? -8.57521  0.33932   -4.93192  1.000 36.07470  ? 181 PHE A CB   1 
ATOM   2729 C CG   . PHE A 1 181 ? -7.43617  0.63730   -5.85398  1.000 36.84756  ? 181 PHE A CG   1 
ATOM   2730 C CD1  . PHE A 1 181 ? -7.35408  0.02146   -7.09077  1.000 33.61138  ? 181 PHE A CD1  1 
ATOM   2731 C CD2  . PHE A 1 181 ? -6.44756  1.53504   -5.48834  1.000 38.24646  ? 181 PHE A CD2  1 
ATOM   2732 C CE1  . PHE A 1 181 ? -6.30659  0.29451   -7.94864  1.000 36.86809  ? 181 PHE A CE1  1 
ATOM   2733 C CE2  . PHE A 1 181 ? -5.39685  1.81100   -6.34109  1.000 38.81918  ? 181 PHE A CE2  1 
ATOM   2734 C CZ   . PHE A 1 181 ? -5.32710  1.18914   -7.57520  1.000 36.60587  ? 181 PHE A CZ   1 
ATOM   2735 H H    . PHE A 1 181 ? -9.31151  2.20934   -3.55542  1.000 44.70204  ? 181 PHE A H    1 
ATOM   2736 H HA   . PHE A 1 181 ? -9.74559  1.60127   -6.06178  1.000 46.39870  ? 181 PHE A HA   1 
ATOM   2737 H HB2  . PHE A 1 181 ? -8.26731  0.48624   -4.02389  1.000 43.28341  ? 181 PHE A HB2  1 
ATOM   2738 H HB3  . PHE A 1 181 ? -8.81850  -0.59181  -5.05317  1.000 43.28341  ? 181 PHE A HB3  1 
ATOM   2739 H HD1  . PHE A 1 181 ? -8.01218  -0.58352  -7.34729  1.000 40.32742  ? 181 PHE A HD1  1 
ATOM   2740 H HD2  . PHE A 1 181 ? -6.49149  1.95634   -4.66041  1.000 45.88952  ? 181 PHE A HD2  1 
ATOM   2741 H HE1  . PHE A 1 181 ? -6.26231  -0.12497  -8.77748  1.000 44.23548  ? 181 PHE A HE1  1 
ATOM   2742 H HE2  . PHE A 1 181 ? -4.73668  2.41435   -6.08605  1.000 46.57678  ? 181 PHE A HE2  1 
ATOM   2743 H HZ   . PHE A 1 181 ? -4.62092  1.37446   -8.15128  1.000 43.92082  ? 181 PHE A HZ   1 
ATOM   2744 N N    . TYR A 1 182 ? -11.49572 -0.09894  -6.31093  1.000 31.17703  ? 182 TYR A N    1 
ATOM   2745 C CA   . TYR A 1 182 ? -12.36604 -1.26139  -6.39650  1.000 35.48703  ? 182 TYR A CA   1 
ATOM   2746 C C    . TYR A 1 182 ? -11.51521 -2.50074  -6.14836  1.000 32.76599  ? 182 TYR A C    1 
ATOM   2747 O O    . TYR A 1 182 ? -10.52410 -2.72953  -6.85020  1.000 37.59061  ? 182 TYR A O    1 
ATOM   2748 C CB   . TYR A 1 182 ? -13.04907 -1.33429  -7.76106  1.000 34.82648  ? 182 TYR A CB   1 
ATOM   2749 C CG   . TYR A 1 182 ? -14.07167 -0.24323  -8.01170  1.000 33.45811  ? 182 TYR A CG   1 
ATOM   2750 C CD1  . TYR A 1 182 ? -15.36206 -0.34335  -7.50552  1.000 35.36015  ? 182 TYR A CD1  1 
ATOM   2751 C CD2  . TYR A 1 182 ? -13.75160 0.87784   -8.76776  1.000 32.18734  ? 182 TYR A CD2  1 
ATOM   2752 C CE1  . TYR A 1 182 ? -16.30192 0.64474   -7.73484  1.000 29.43030  ? 182 TYR A CE1  1 
ATOM   2753 C CE2  . TYR A 1 182 ? -14.68738 1.87731   -8.99966  1.000 35.26876  ? 182 TYR A CE2  1 
ATOM   2754 C CZ   . TYR A 1 182 ? -15.96306 1.75100   -8.47939  1.000 36.11114  ? 182 TYR A CZ   1 
ATOM   2755 O OH   . TYR A 1 182 ? -16.90969 2.72750   -8.69956  1.000 35.58543  ? 182 TYR A OH   1 
ATOM   2756 H H    . TYR A 1 182 ? -11.30704 0.26284   -7.06798  1.000 37.40621  ? 182 TYR A H    1 
ATOM   2757 H HA   . TYR A 1 182 ? -13.07000 -1.20412  -5.73162  1.000 42.57821  ? 182 TYR A HA   1 
ATOM   2758 H HB2  . TYR A 1 182 ? -12.37035 -1.26352  -8.45043  1.000 41.78555  ? 182 TYR A HB2  1 
ATOM   2759 H HB3  . TYR A 1 182 ? -13.50671 -2.18658  -7.83232  1.000 41.78555  ? 182 TYR A HB3  1 
ATOM   2760 H HD1  . TYR A 1 182 ? -15.59807 -1.08932  -7.00281  1.000 42.42595  ? 182 TYR A HD1  1 
ATOM   2761 H HD2  . TYR A 1 182 ? -12.89662 0.96015   -9.12433  1.000 38.61858  ? 182 TYR A HD2  1 
ATOM   2762 H HE1  . TYR A 1 182 ? -17.16038 0.56175   -7.38688  1.000 35.31014  ? 182 TYR A HE1  1 
ATOM   2763 H HE2  . TYR A 1 182 ? -14.45817 2.62624   -9.50114  1.000 42.31629  ? 182 TYR A HE2  1 
ATOM   2764 H HH   . TYR A 1 182 ? -16.59188 3.33013   -9.19092  1.000 42.69629  ? 182 TYR A HH   1 
ATOM   2765 N N    . GLY A 1 183 ? -11.87133 -3.27661  -5.13201  1.000 37.13465  ? 183 GLY A N    1 
ATOM   2766 C CA   . GLY A 1 183 ? -11.14144 -4.47768  -4.81218  1.000 34.62023  ? 183 GLY A CA   1 
ATOM   2767 C C    . GLY A 1 183 ? -9.94716  -4.21767  -3.91553  1.000 39.66851  ? 183 GLY A C    1 
ATOM   2768 O O    . GLY A 1 183 ? -9.63047  -3.07744  -3.56338  1.000 40.92971  ? 183 GLY A O    1 
ATOM   2769 H H    . GLY A 1 183 ? -12.53896 -3.12106  -4.61271  1.000 44.55535  ? 183 GLY A H    1 
ATOM   2770 H HA2  . GLY A 1 183 ? -11.73213 -5.09942  -4.35894  1.000 41.53805  ? 183 GLY A HA2  1 
ATOM   2771 H HA3  . GLY A 1 183 ? -10.82258 -4.88580  -5.63234  1.000 41.53805  ? 183 GLY A HA3  1 
ATOM   2772 N N    . PRO A 1 184 ? -9.26410  -5.29150  -3.53806  1.000 33.58731  ? 184 PRO A N    1 
ATOM   2773 C CA   . PRO A 1 184 ? -8.13646  -5.20020  -2.58709  1.000 42.95409  ? 184 PRO A CA   1 
ATOM   2774 C C    . PRO A 1 184 ? -6.80482  -4.88999  -3.26230  1.000 47.48677  ? 184 PRO A C    1 
ATOM   2775 O O    . PRO A 1 184 ? -5.81035  -5.60279  -3.07419  1.000 48.45542  ? 184 PRO A O    1 
ATOM   2776 C CB   . PRO A 1 184 ? -8.13227  -6.59066  -1.95543  1.000 38.42400  ? 184 PRO A CB   1 
ATOM   2777 C CG   . PRO A 1 184 ? -8.54638  -7.47865  -3.09482  1.000 48.51927  ? 184 PRO A CG   1 
ATOM   2778 C CD   . PRO A 1 184 ? -9.59484  -6.68907  -3.85306  1.000 37.73908  ? 184 PRO A CD   1 
ATOM   2779 H HA   . PRO A 1 184 ? -8.31888  -4.52819  -1.91180  1.000 51.53868  ? 184 PRO A HA   1 
ATOM   2780 H HB2  . PRO A 1 184 ? -7.24422  -6.81463  -1.63590  1.000 46.10258  ? 184 PRO A HB2  1 
ATOM   2781 H HB3  . PRO A 1 184 ? -8.76823  -6.63218  -1.22418  1.000 46.10258  ? 184 PRO A HB3  1 
ATOM   2782 H HG2  . PRO A 1 184 ? -7.78110  -7.66899  -3.65964  1.000 58.21689  ? 184 PRO A HG2  1 
ATOM   2783 H HG3  . PRO A 1 184 ? -8.91823  -8.30561  -2.75020  1.000 58.21689  ? 184 PRO A HG3  1 
ATOM   2784 H HD2  . PRO A 1 184 ? -9.52683  -6.85284  -4.80671  1.000 45.28067  ? 184 PRO A HD2  1 
ATOM   2785 H HD3  . PRO A 1 184 ? -10.48604 -6.91111  -3.54104  1.000 45.28067  ? 184 PRO A HD3  1 
ATOM   2786 N N    . PHE A 1 185 ? -6.76477  -3.82440  -4.05040  1.000 39.71113  ? 185 PHE A N    1 
ATOM   2787 C CA   . PHE A 1 185 ? -5.58895  -3.50189  -4.84005  1.000 39.07574  ? 185 PHE A CA   1 
ATOM   2788 C C    . PHE A 1 185 ? -4.95119  -2.21187  -4.34873  1.000 41.72560  ? 185 PHE A C    1 
ATOM   2789 O O    . PHE A 1 185 ? -5.62173  -1.32832  -3.80518  1.000 41.86844  ? 185 PHE A O    1 
ATOM   2790 C CB   . PHE A 1 185 ? -5.94594  -3.38820  -6.32340  1.000 42.33739  ? 185 PHE A CB   1 
ATOM   2791 C CG   . PHE A 1 185 ? -6.64771  -4.59876  -6.85695  1.000 34.65007  ? 185 PHE A CG   1 
ATOM   2792 C CD1  . PHE A 1 185 ? -6.03355  -5.83920  -6.82109  1.000 36.20556  ? 185 PHE A CD1  1 
ATOM   2793 C CD2  . PHE A 1 185 ? -7.92644  -4.50313  -7.37505  1.000 34.87380  ? 185 PHE A CD2  1 
ATOM   2794 C CE1  . PHE A 1 185 ? -6.68122  -6.96125  -7.29854  1.000 44.38515  ? 185 PHE A CE1  1 
ATOM   2795 C CE2  . PHE A 1 185 ? -8.57850  -5.62023  -7.85742  1.000 35.54546  ? 185 PHE A CE2  1 
ATOM   2796 C CZ   . PHE A 1 185 ? -7.95736  -6.84954  -7.81981  1.000 35.76660  ? 185 PHE A CZ   1 
ATOM   2797 H H    . PHE A 1 185 ? -7.41412  -3.26839  -4.14418  1.000 47.64712  ? 185 PHE A H    1 
ATOM   2798 H HA   . PHE A 1 185 ? -4.92953  -4.20637  -4.74117  1.000 46.88466  ? 185 PHE A HA   1 
ATOM   2799 H HB2  . PHE A 1 185 ? -6.53160  -2.62501  -6.44766  1.000 50.79864  ? 185 PHE A HB2  1 
ATOM   2800 H HB3  . PHE A 1 185 ? -5.13023  -3.26706  -6.83413  1.000 50.79864  ? 185 PHE A HB3  1 
ATOM   2801 H HD1  . PHE A 1 185 ? -5.17530  -5.91747  -6.47154  1.000 43.44045  ? 185 PHE A HD1  1 
ATOM   2802 H HD2  . PHE A 1 185 ? -8.35203  -3.67657  -7.39876  1.000 41.84233  ? 185 PHE A HD2  1 
ATOM   2803 H HE1  . PHE A 1 185 ? -6.26037  -7.79008  -7.26969  1.000 53.25596  ? 185 PHE A HE1  1 
ATOM   2804 H HE2  . PHE A 1 185 ? -9.43660  -5.54308  -8.20758  1.000 42.64832  ? 185 PHE A HE2  1 
ATOM   2805 H HZ   . PHE A 1 185 ? -8.39551  -7.60291  -8.14440  1.000 42.91369  ? 185 PHE A HZ   1 
ATOM   2806 N N    . VAL A 1 186 ? -3.63613  -2.13096  -4.53565  1.000 37.97396  ? 186 VAL A N    1 
ATOM   2807 C CA   . VAL A 1 186 ? -2.84560  -0.96365  -4.17809  1.000 36.20696  ? 186 VAL A CA   1 
ATOM   2808 C C    . VAL A 1 186 ? -2.07016  -0.52575  -5.41124  1.000 35.25279  ? 186 VAL A C    1 
ATOM   2809 O O    . VAL A 1 186 ? -1.69261  -1.34532  -6.25512  1.000 33.00361  ? 186 VAL A O    1 
ATOM   2810 C CB   . VAL A 1 186 ? -1.89008  -1.25656  -2.99945  1.000 35.91581  ? 186 VAL A CB   1 
ATOM   2811 C CG1  . VAL A 1 186 ? -2.66344  -1.85383  -1.83332  1.000 38.40158  ? 186 VAL A CG1  1 
ATOM   2812 C CG2  . VAL A 1 186 ? -0.75543  -2.19005  -3.43679  1.000 29.53972  ? 186 VAL A CG2  1 
ATOM   2813 H H    . VAL A 1 186 ? -3.16587  -2.76319  -4.88024  1.000 45.56252  ? 186 VAL A H    1 
ATOM   2814 H HA   . VAL A 1 186 ? -3.43188  -0.23893  -3.90984  1.000 43.44213  ? 186 VAL A HA   1 
ATOM   2815 H HB   . VAL A 1 186 ? -1.48879  -0.42401  -2.70497  1.000 43.09274  ? 186 VAL A HB   1 
ATOM   2816 H HG11 . VAL A 1 186 ? -3.03814  -2.70590  -2.10622  1.000 46.07567  ? 186 VAL A HG11 1 
ATOM   2817 H HG12 . VAL A 1 186 ? -2.05851  -1.98261  -1.08608  1.000 46.07567  ? 186 VAL A HG12 1 
ATOM   2818 H HG13 . VAL A 1 186 ? -3.37527  -1.24490  -1.58151  1.000 46.07567  ? 186 VAL A HG13 1 
ATOM   2819 H HG21 . VAL A 1 186 ? -0.39243  -2.63398  -2.65445  1.000 35.44144  ? 186 VAL A HG21 1 
ATOM   2820 H HG22 . VAL A 1 186 ? -1.10856  -2.84769  -4.05623  1.000 35.44144  ? 186 VAL A HG22 1 
ATOM   2821 H HG23 . VAL A 1 186 ? -0.06407  -1.66538  -3.86998  1.000 35.44144  ? 186 VAL A HG23 1 
ATOM   2822 N N    . ASP A 1 187 ? -1.84037  0.78305   -5.51574  1.000 37.65101  ? 187 ASP A N    1 
ATOM   2823 C CA   . ASP A 1 187 ? -1.13427  1.35776   -6.66155  1.000 37.49623  ? 187 ASP A CA   1 
ATOM   2824 C C    . ASP A 1 187 ? 0.37524   1.29042   -6.41703  1.000 40.11801  ? 187 ASP A C    1 
ATOM   2825 O O    . ASP A 1 187 ? 1.07403   2.29342   -6.26090  1.000 39.26187  ? 187 ASP A O    1 
ATOM   2826 C CB   . ASP A 1 187 ? -1.61239  2.78208   -6.92508  1.000 35.95277  ? 187 ASP A CB   1 
ATOM   2827 C CG   . ASP A 1 187 ? -1.65301  3.63559   -5.67053  1.000 38.02806  ? 187 ASP A CG   1 
ATOM   2828 O OD1  . ASP A 1 187 ? -1.83445  3.07840   -4.56923  1.000 42.06331  ? 187 ASP A OD1  1 
ATOM   2829 O OD2  . ASP A 1 187 ? -1.51695  4.86982   -5.78878  1.000 38.65914  ? 187 ASP A OD2  1 
ATOM   2830 H H    . ASP A 1 187 ? -2.08548  1.36429   -4.93120  1.000 45.17499  ? 187 ASP A H    1 
ATOM   2831 H HA   . ASP A 1 187 ? -1.33224  0.82886   -7.45020  1.000 44.98925  ? 187 ASP A HA   1 
ATOM   2832 H HB2  . ASP A 1 187 ? -1.00884  3.20561   -7.55536  1.000 43.13710  ? 187 ASP A HB2  1 
ATOM   2833 H HB3  . ASP A 1 187 ? -2.50885  2.75040   -7.29423  1.000 43.13710  ? 187 ASP A HB3  1 
ATOM   2834 N N    . ARG A 1 188 ? 0.86648   0.05366   -6.38517  1.000 38.50935  ? 188 ARG A N    1 
ATOM   2835 C CA   . ARG A 1 188 ? 2.28381   -0.25585  -6.26761  1.000 38.69341  ? 188 ARG A CA   1 
ATOM   2836 C C    . ARG A 1 188 ? 2.59329   -1.36554  -7.25940  1.000 39.06881  ? 188 ARG A C    1 
ATOM   2837 O O    . ARG A 1 188 ? 1.75622   -2.24009  -7.49541  1.000 40.54755  ? 188 ARG A O    1 
ATOM   2838 C CB   . ARG A 1 188 ? 2.64606   -0.68748  -4.83609  1.000 42.80838  ? 188 ARG A CB   1 
ATOM   2839 C CG   . ARG A 1 188 ? 4.04669   -1.26589  -4.66886  1.000 48.92277  ? 188 ARG A CG   1 
ATOM   2840 C CD   . ARG A 1 188 ? 4.26456   -1.80689  -3.25466  1.000 63.25201  ? 188 ARG A CD   1 
ATOM   2841 N NE   . ARG A 1 188 ? 5.57538   -2.42928  -3.10372  1.000 66.37579  ? 188 ARG A NE   1 
ATOM   2842 C CZ   . ARG A 1 188 ? 5.90196   -3.27432  -2.13427  1.000 75.81601  ? 188 ARG A CZ   1 
ATOM   2843 N NH1  . ARG A 1 188 ? 5.03028   -3.63127  -1.20381  1.000 71.29241  ? 188 ARG A NH1  1 
ATOM   2844 N NH2  . ARG A 1 188 ? 7.13165   -3.78133  -2.10313  1.000 74.81074  ? 188 ARG A NH2  1 
ATOM   2845 H H    . ARG A 1 188 ? 0.37586   -0.65110  -6.43227  1.000 46.20500  ? 188 ARG A H    1 
ATOM   2846 H HA   . ARG A 1 188 ? 2.82882   0.51794   -6.48000  1.000 46.42586  ? 188 ARG A HA   1 
ATOM   2847 H HB2  . ARG A 1 188 ? 2.58109   0.08769   -4.25662  1.000 51.36383  ? 188 ARG A HB2  1 
ATOM   2848 H HB3  . ARG A 1 188 ? 2.01539   -1.36764  -4.55228  1.000 51.36383  ? 188 ARG A HB3  1 
ATOM   2849 H HG2  . ARG A 1 188 ? 4.17030   -1.99499  -5.29659  1.000 58.70110  ? 188 ARG A HG2  1 
ATOM   2850 H HG3  . ARG A 1 188 ? 4.70309   -0.57108  -4.83397  1.000 58.70110  ? 188 ARG A HG3  1 
ATOM   2851 H HD2  . ARG A 1 188 ? 4.20128   -1.07603  -2.62004  1.000 75.89619  ? 188 ARG A HD2  1 
ATOM   2852 H HD3  . ARG A 1 188 ? 3.58805   -2.47437  -3.06049  1.000 75.89619  ? 188 ARG A HD3  1 
ATOM   2853 H HE   . ARG A 1 188 ? 6.17927   -2.23465  -3.68428  1.000 79.64472  ? 188 ARG A HE   1 
ATOM   2854 H HH11 . ARG A 1 188 ? 4.23113   -3.31389  -1.21886  1.000 85.54466  ? 188 ARG A HH11 1 
ATOM   2855 H HH12 . ARG A 1 188 ? 5.26324   -4.18050  -0.58440  1.000 85.54466  ? 188 ARG A HH12 1 
ATOM   2856 H HH21 . ARG A 1 188 ? 7.70327   -3.56039  -2.70649  1.000 89.76666  ? 188 ARG A HH21 1 
ATOM   2857 H HH22 . ARG A 1 188 ? 7.35489   -4.33000  -1.47965  1.000 89.76666  ? 188 ARG A HH22 1 
ATOM   2858 N N    . GLN A 1 189 ? 3.78711   -1.32673  -7.84969  1.000 47.08401  ? 189 GLN A N    1 
ATOM   2859 C CA   . GLN A 1 189 ? 4.19515   -2.36471  -8.79684  1.000 43.87364  ? 189 GLN A CA   1 
ATOM   2860 C C    . GLN A 1 189 ? 4.72241   -3.55848  -8.00420  1.000 47.11618  ? 189 GLN A C    1 
ATOM   2861 O O    . GLN A 1 189 ? 5.92616   -3.80928  -7.90232  1.000 42.30412  ? 189 GLN A O    1 
ATOM   2862 C CB   . GLN A 1 189 ? 5.23125   -1.83315  -9.77540  1.000 42.75820  ? 189 GLN A CB   1 
ATOM   2863 C CG   . GLN A 1 189 ? 5.61703   -2.83161  -10.84746 1.000 40.64114  ? 189 GLN A CG   1 
ATOM   2864 C CD   . GLN A 1 189 ? 6.58954   -2.25076  -11.84964 1.000 45.71350  ? 189 GLN A CD   1 
ATOM   2865 O OE1  . GLN A 1 189 ? 6.36100   -1.17303  -12.39853 1.000 47.60576  ? 189 GLN A OE1  1 
ATOM   2866 N NE2  . GLN A 1 189 ? 7.68619   -2.96009  -12.09100 1.000 43.14283  ? 189 GLN A NE2  1 
ATOM   2867 H H    . GLN A 1 189 ? 4.37533   -0.71312  -7.71901  1.000 56.49459  ? 189 GLN A H    1 
ATOM   2868 H HA   . GLN A 1 189 ? 3.42118   -2.65045  -9.30696  1.000 52.64214  ? 189 GLN A HA   1 
ATOM   2869 H HB2  . GLN A 1 189 ? 4.87121   -1.04773  -10.21629 1.000 51.30361  ? 189 GLN A HB2  1 
ATOM   2870 H HB3  . GLN A 1 189 ? 6.03431   -1.59906  -9.28429  1.000 51.30361  ? 189 GLN A HB3  1 
ATOM   2871 H HG2  . GLN A 1 189 ? 6.03676   -3.59998  -10.42994 1.000 48.76314  ? 189 GLN A HG2  1 
ATOM   2872 H HG3  . GLN A 1 189 ? 4.81982   -3.10822  -11.32585 1.000 48.76314  ? 189 GLN A HG3  1 
ATOM   2873 H HE21 . GLN A 1 189 ? 7.81273   -3.70769  -11.68519 1.000 51.76517  ? 189 GLN A HE21 1 
ATOM   2874 H HE22 . GLN A 1 189 ? 8.26973   -2.67179  -12.65311 1.000 51.76517  ? 189 GLN A HE22 1 
ATOM   2875 N N    . THR A 1 190 ? 3.78710   -4.31158  -7.43265  1.000 44.49843  ? 190 THR A N    1 
ATOM   2876 C CA   . THR A 1 190 ? 4.11439   -5.47400  -6.62319  1.000 55.17123  ? 190 THR A CA   1 
ATOM   2877 C C    . THR A 1 190 ? 3.15990   -6.60089  -6.98840  1.000 51.45684  ? 190 THR A C    1 
ATOM   2878 O O    . THR A 1 190 ? 2.19112   -6.41037  -7.72822  1.000 50.87883  ? 190 THR A O    1 
ATOM   2879 C CB   . THR A 1 190 ? 4.04845   -5.15701  -5.11941  1.000 47.69844  ? 190 THR A CB   1 
ATOM   2880 O OG1  . THR A 1 190 ? 4.55984   -6.26920  -4.37447  1.000 62.71044  ? 190 THR A OG1  1 
ATOM   2881 C CG2  . THR A 1 190 ? 2.61798   -4.85867  -4.67261  1.000 48.83154  ? 190 THR A CG2  1 
ATOM   2882 H H    . THR A 1 190 ? 2.94256   -4.16473  -7.50192  1.000 53.39188  ? 190 THR A H    1 
ATOM   2883 H HA   . THR A 1 190 ? 5.01838   -5.76459  -6.82131  1.000 66.19925  ? 190 THR A HA   1 
ATOM   2884 H HB   . THR A 1 190 ? 4.58246   -4.36749  -4.93945  1.000 57.23190  ? 190 THR A HB   1 
ATOM   2885 H HG1  . THR A 1 190 ? 5.37854   -6.36942  -4.53347  1.000 75.24630  ? 190 THR A HG1  1 
ATOM   2886 H HG21 . THR A 1 190 ? 2.60671   -4.62231  -3.73191  1.000 58.59162  ? 190 THR A HG21 1 
ATOM   2887 H HG22 . THR A 1 190 ? 2.25695   -4.11990  -5.18717  1.000 58.59162  ? 190 THR A HG22 1 
ATOM   2888 H HG23 . THR A 1 190 ? 2.05854   -5.63949  -4.80772  1.000 58.59162  ? 190 THR A HG23 1 
ATOM   2889 N N    . ALA A 1 191 ? 3.44561   -7.78704  -6.46011  1.000 54.14389  ? 191 ALA A N    1 
ATOM   2890 C CA   . ALA A 1 191 ? 2.67232   -8.97911  -6.79018  1.000 55.32502  ? 191 ALA A CA   1 
ATOM   2891 C C    . ALA A 1 191 ? 1.25335   -8.84638  -6.25086  1.000 52.04863  ? 191 ALA A C    1 
ATOM   2892 O O    . ALA A 1 191 ? 1.03083   -8.92053  -5.03822  1.000 60.91545  ? 191 ALA A O    1 
ATOM   2893 C CB   . ALA A 1 191 ? 3.35460   -10.21934 -6.22125  1.000 64.51459  ? 191 ALA A CB   1 
ATOM   2894 H H    . ALA A 1 191 ? 4.08651   -7.92852  -5.90439  1.000 64.96644  ? 191 ALA A H    1 
ATOM   2895 H HA   . ALA A 1 191 ? 2.62387   -9.06591  -7.75507  1.000 66.38380  ? 191 ALA A HA   1 
ATOM   2896 H HB1  . ALA A 1 191 ? 2.81151   -10.99796 -6.42049  1.000 77.41128  ? 191 ALA A HB1  1 
ATOM   2897 H HB2  . ALA A 1 191 ? 4.22975   -10.31336 -6.62891  1.000 77.41128  ? 191 ALA A HB2  1 
ATOM   2898 H HB3  . ALA A 1 191 ? 3.44626   -10.11690 -5.26104  1.000 77.41128  ? 191 ALA A HB3  1 
ATOM   2899 N N    . GLN A 1 192 ? 0.29285   -8.64760  -7.15115  1.000 55.03842  ? 192 GLN A N    1 
ATOM   2900 C CA   . GLN A 1 192 ? -1.12247  -8.68039  -6.81831  1.000 56.68082  ? 192 GLN A CA   1 
ATOM   2901 C C    . GLN A 1 192 ? -1.85085  -9.52807  -7.84971  1.000 52.41964  ? 192 GLN A C    1 
ATOM   2902 O O    . GLN A 1 192 ? -1.42646  -9.62688  -9.00471  1.000 52.89224  ? 192 GLN A O    1 
ATOM   2903 C CB   . GLN A 1 192 ? -1.75046  -7.28457  -6.79358  1.000 50.62253  ? 192 GLN A CB   1 
ATOM   2904 C CG   . GLN A 1 192 ? -1.09874  -6.31184  -5.84895  1.000 48.57466  ? 192 GLN A CG   1 
ATOM   2905 C CD   . GLN A 1 192 ? -1.58017  -4.90006  -6.07974  1.000 44.70987  ? 192 GLN A CD   1 
ATOM   2906 O OE1  . GLN A 1 192 ? -2.63368  -4.50101  -5.58429  1.000 54.46019  ? 192 GLN A OE1  1 
ATOM   2907 N NE2  . GLN A 1 192 ? -0.81542  -4.13578  -6.84736  1.000 48.52882  ? 192 GLN A NE2  1 
ATOM   2908 H H    . GLN A 1 192 ? 0.44369   -8.48787  -7.98262  1.000 66.03988  ? 192 GLN A H    1 
ATOM   2909 H HA   . GLN A 1 192 ? -1.23041  -9.07190  -5.93742  1.000 68.01076  ? 192 GLN A HA   1 
ATOM   2910 H HB2  . GLN A 1 192 ? -1.69408  -6.90660  -7.68513  1.000 60.74080  ? 192 GLN A HB2  1 
ATOM   2911 H HB3  . GLN A 1 192 ? -2.67938  -7.37039  -6.52776  1.000 60.74080  ? 192 GLN A HB3  1 
ATOM   2912 H HG2  . GLN A 1 192 ? -1.31217  -6.56059  -4.93600  1.000 58.28336  ? 192 GLN A HG2  1 
ATOM   2913 H HG3  . GLN A 1 192 ? -0.13813  -6.33125  -5.98215  1.000 58.28336  ? 192 GLN A HG3  1 
ATOM   2914 H HE21 . GLN A 1 192 ? -0.08968  -4.45273  -7.18268  1.000 58.22836  ? 192 GLN A HE21 1 
ATOM   2915 H HE22 . GLN A 1 192 ? -1.04516  -3.32313  -7.00991  1.000 58.22836  ? 192 GLN A HE22 1 
ATOM   2916 N N    . ALA A 1 193 ? -2.95483  -10.13619 -7.42400  1.000 51.61573  ? 193 ALA A N    1 
ATOM   2917 C CA   . ALA A 1 193 ? -3.81187  -10.89690 -8.32061  1.000 62.82542  ? 193 ALA A CA   1 
ATOM   2918 C C    . ALA A 1 193 ? -5.26022  -10.70026 -7.89924  1.000 54.53991  ? 193 ALA A C    1 
ATOM   2919 O O    . ALA A 1 193 ? -5.55786  -10.47552 -6.72292  1.000 49.24038  ? 193 ALA A O    1 
ATOM   2920 C CB   . ALA A 1 193 ? -3.45456  -12.38784 -8.33167  1.000 50.64857  ? 193 ALA A CB   1 
ATOM   2921 H H    . ALA A 1 193 ? -3.23002  -10.12114 -6.60936  1.000 61.93265  ? 193 ALA A H    1 
ATOM   2922 H HA   . ALA A 1 193 ? -3.71051  -10.56798 -9.22750  1.000 75.38427  ? 193 ALA A HA   1 
ATOM   2923 H HB1  . ALA A 1 193 ? -4.01386  -12.84181 -8.98128  1.000 60.77206  ? 193 ALA A HB1  1 
ATOM   2924 H HB2  . ALA A 1 193 ? -2.52027  -12.48690 -8.57294  1.000 60.77206  ? 193 ALA A HB2  1 
ATOM   2925 H HB3  . ALA A 1 193 ? -3.60874  -12.75610 -7.44764  1.000 60.77206  ? 193 ALA A HB3  1 
ATOM   2926 N N    . ALA A 1 194 ? -6.16123  -10.81079 -8.87650  1.000 52.39692  ? 194 ALA A N    1 
ATOM   2927 C CA   . ALA A 1 194 ? -7.52844  -10.34165 -8.68263  1.000 54.98071  ? 194 ALA A CA   1 
ATOM   2928 C C    . ALA A 1 194 ? -8.32836  -11.26884 -7.77747  1.000 65.99433  ? 194 ALA A C    1 
ATOM   2929 O O    . ALA A 1 194 ? -9.06594  -10.80248 -6.90044  1.000 72.54452  ? 194 ALA A O    1 
ATOM   2930 C CB   . ALA A 1 194 ? -8.22013  -10.20131 -10.03744 1.000 47.74987  ? 194 ALA A CB   1 
ATOM   2931 H H    . ALA A 1 194 ? -6.00691  -11.14984 -9.65163  1.000 62.87008  ? 194 ALA A H    1 
ATOM   2932 H HA   . ALA A 1 194 ? -7.49549  -9.47147  -8.25531  1.000 65.97062  ? 194 ALA A HA   1 
ATOM   2933 H HB1  . ALA A 1 194 ? -9.13377  -9.90747  -9.89663  1.000 57.29362  ? 194 ALA A HB1  1 
ATOM   2934 H HB2  . ALA A 1 194 ? -7.74092  -9.54777  -10.57048 1.000 57.29362  ? 194 ALA A HB2  1 
ATOM   2935 H HB3  . ALA A 1 194 ? -8.21469  -11.06164 -10.48542 1.000 57.29362  ? 194 ALA A HB3  1 
ATOM   2936 N N    . GLY A 1 195 ? -8.20444  -12.56744 -7.97446  1.000 55.09727  ? 195 GLY A N    1 
ATOM   2937 C CA   . GLY A 1 195 ? -9.09877  -13.51009 -7.33987  1.000 57.14286  ? 195 GLY A CA   1 
ATOM   2938 C C    . GLY A 1 195 ? -10.10479 -14.06828 -8.33444  1.000 57.24949  ? 195 GLY A C    1 
ATOM   2939 O O    . GLY A 1 195 ? -10.44949 -13.43295 -9.34136  1.000 49.10226  ? 195 GLY A O    1 
ATOM   2940 H H    . GLY A 1 195 ? -7.60590  -12.92923 -8.47490  1.000 66.11050  ? 195 GLY A H    1 
ATOM   2941 H HA2  . GLY A 1 195 ? -8.58707  -14.24620 -6.96945  1.000 68.56520  ? 195 GLY A HA2  1 
ATOM   2942 H HA3  . GLY A 1 195 ? -9.58201  -13.06939 -6.62352  1.000 68.56520  ? 195 GLY A HA3  1 
ATOM   2943 N N    . THR A 1 196 ? -10.58391 -15.27647 -8.04684  1.000 68.74312  ? 196 THR A N    1 
ATOM   2944 C CA   . THR A 1 196 ? -11.47775 -15.97390 -8.96105  1.000 56.57883  ? 196 THR A CA   1 
ATOM   2945 C C    . THR A 1 196 ? -12.66864 -15.10156 -9.32916  1.000 53.91332  ? 196 THR A C    1 
ATOM   2946 O O    . THR A 1 196 ? -13.30143 -14.49000 -8.46327  1.000 47.62392  ? 196 THR A O    1 
ATOM   2947 C CB   . THR A 1 196 ? -11.95800 -17.28063 -8.32736  1.000 54.42165  ? 196 THR A CB   1 
ATOM   2948 O OG1  . THR A 1 196 ? -10.87983 -18.22464 -8.30344  1.000 64.08055  ? 196 THR A OG1  1 
ATOM   2949 C CG2  . THR A 1 196 ? -13.11984 -17.85940 -9.11130  1.000 61.29667  ? 196 THR A CG2  1 
ATOM   2950 H H    . THR A 1 196 ? -10.40543 -15.71296 -7.32766  1.000 82.48552  ? 196 THR A H    1 
ATOM   2951 H HA   . THR A 1 196 ? -10.99465 -16.18683 -9.77479  1.000 67.88837  ? 196 THR A HA   1 
ATOM   2952 H HB   . THR A 1 196 ? -12.25910 -17.11027 -7.42115  1.000 65.29975  ? 196 THR A HB   1 
ATOM   2953 H HG1  . THR A 1 196 ? -10.55290 -18.30693 -9.07282  1.000 76.89043  ? 196 THR A HG1  1 
ATOM   2954 H HG21 . THR A 1 196 ? -13.94008 -17.39661 -8.87905  1.000 73.54977  ? 196 THR A HG21 1 
ATOM   2955 H HG22 . THR A 1 196 ? -12.96058 -17.75938 -10.06289 1.000 73.54977  ? 196 THR A HG22 1 
ATOM   2956 H HG23 . THR A 1 196 ? -13.22144 -18.80207 -8.90650  1.000 73.54977  ? 196 THR A HG23 1 
ATOM   2957 N N    . ASP A 1 197 ? -12.96746 -15.05128 -10.62356 1.000 48.18294  ? 197 ASP A N    1 
ATOM   2958 C CA   . ASP A 1 197 ? -14.08304 -14.27699 -11.14002 1.000 50.74478  ? 197 ASP A CA   1 
ATOM   2959 C C    . ASP A 1 197 ? -15.28052 -15.18259 -11.39734 1.000 55.40284  ? 197 ASP A C    1 
ATOM   2960 O O    . ASP A 1 197 ? -15.13230 -16.36999 -11.69626 1.000 55.79881  ? 197 ASP A O    1 
ATOM   2961 C CB   . ASP A 1 197 ? -13.70558 -13.55457 -12.43247 1.000 50.28994  ? 197 ASP A CB   1 
ATOM   2962 C CG   . ASP A 1 197 ? -14.67899 -12.44515 -12.77109 1.000 46.05398  ? 197 ASP A CG   1 
ATOM   2963 O OD1  . ASP A 1 197 ? -15.36744 -11.97452 -11.84021 1.000 42.37406  ? 197 ASP A OD1  1 
ATOM   2964 O OD2  . ASP A 1 197 ? -14.76759 -12.05240 -13.95392 1.000 42.27336  ? 197 ASP A OD2  1 
ATOM   2965 H H    . ASP A 1 197 ? -12.52674 -15.46779 -11.23338 1.000 57.81330  ? 197 ASP A H    1 
ATOM   2966 H HA   . ASP A 1 197 ? -14.33366 -13.60917 -10.48268 1.000 60.88751  ? 197 ASP A HA   1 
ATOM   2967 H HB2  . ASP A 1 197 ? -12.82362 -13.16330 -12.33274 1.000 60.34170  ? 197 ASP A HB2  1 
ATOM   2968 H HB3  . ASP A 1 197 ? -13.70538 -14.19086 -13.16462 1.000 60.34170  ? 197 ASP A HB3  1 
ATOM   2969 N N    . THR A 1 198 ? -16.47433 -14.60647 -11.28356 1.000 46.81916  ? 198 THR A N    1 
ATOM   2970 C CA   . THR A 1 198 ? -17.71161 -15.34893 -11.45732 1.000 47.49498  ? 198 THR A CA   1 
ATOM   2971 C C    . THR A 1 198 ? -18.59118 -14.65331 -12.48694 1.000 46.29933  ? 198 THR A C    1 
ATOM   2972 O O    . THR A 1 198 ? -18.44808 -13.45738 -12.75799 1.000 38.85124  ? 198 THR A O    1 
ATOM   2973 C CB   . THR A 1 198 ? -18.47702 -15.49428 -10.13070 1.000 56.17515  ? 198 THR A CB   1 
ATOM   2974 O OG1  . THR A 1 198 ? -18.87176 -14.20137 -9.65473  1.000 52.43798  ? 198 THR A OG1  1 
ATOM   2975 C CG2  . THR A 1 198 ? -17.60908 -16.17439 -9.07412  1.000 58.19344  ? 198 THR A CG2  1 
ATOM   2976 H H    . THR A 1 198 ? -16.59152 -13.77375 -11.10340 1.000 56.17676  ? 198 THR A H    1 
ATOM   2977 H HA   . THR A 1 198 ? -17.50375 -16.23652 -11.78878 1.000 56.98775  ? 198 THR A HA   1 
ATOM   2978 H HB   . THR A 1 198 ? -19.26473 -16.04109 -10.27702 1.000 67.40396  ? 198 THR A HB   1 
ATOM   2979 H HG1  . THR A 1 198 ? -19.35430 -13.81969 -10.22664 1.000 62.91935  ? 198 THR A HG1  1 
ATOM   2980 H HG21 . THR A 1 198 ? -17.51063 -15.59493 -8.30247  1.000 69.82590  ? 198 THR A HG21 1 
ATOM   2981 H HG22 . THR A 1 198 ? -18.02028 -17.00655 -8.79247  1.000 69.82590  ? 198 THR A HG22 1 
ATOM   2982 H HG23 . THR A 1 198 ? -16.73068 -16.36493 -9.43882  1.000 69.82590  ? 198 THR A HG23 1 
ATOM   2983 N N    . THR A 1 199 ? -19.51356 -15.42652 -13.05276 1.000 45.55581  ? 199 THR A N    1 
ATOM   2984 C CA   . THR A 1 199 ? -20.43535 -14.90952 -14.05169 1.000 42.51516  ? 199 THR A CA   1 
ATOM   2985 C C    . THR A 1 199 ? -21.56090 -14.12738 -13.38463 1.000 45.38869  ? 199 THR A C    1 
ATOM   2986 O O    . THR A 1 199 ? -22.09145 -14.53309 -12.34624 1.000 43.53647  ? 199 THR A O    1 
ATOM   2987 C CB   . THR A 1 199 ? -21.01230 -16.05488 -14.88385 1.000 42.39578  ? 199 THR A CB   1 
ATOM   2988 O OG1  . THR A 1 199 ? -19.94362 -16.79452 -15.49001 1.000 43.66703  ? 199 THR A OG1  1 
ATOM   2989 C CG2  . THR A 1 199 ? -21.92926 -15.51268 -15.96733 1.000 36.90990  ? 199 THR A CG2  1 
ATOM   2990 H H    . THR A 1 199 ? -19.62499 -16.25997 -12.87239 1.000 54.66074  ? 199 THR A H    1 
ATOM   2991 H HA   . THR A 1 199 ? -19.96273 -14.30900 -14.64910 1.000 51.01197  ? 199 THR A HA   1 
ATOM   2992 H HB   . THR A 1 199 ? -21.52815 -16.64469 -14.31206 1.000 50.86871  ? 199 THR A HB   1 
ATOM   2993 H HG1  . THR A 1 199 ? -19.44569 -16.27600 -15.92453 1.000 52.39421  ? 199 THR A HG1  1 
ATOM   2994 H HG21 . THR A 1 199 ? -22.85441 -15.58133 -15.68397 1.000 44.28566  ? 199 THR A HG21 1 
ATOM   2995 H HG22 . THR A 1 199 ? -21.72183 -14.58137 -16.14208 1.000 44.28566  ? 199 THR A HG22 1 
ATOM   2996 H HG23 . THR A 1 199 ? -21.81217 -16.02018 -16.78564 1.000 44.28566  ? 199 THR A HG23 1 
ATOM   2997 N N    . ILE A 1 200 ? -21.92987 -13.00280 -13.99513 1.000 43.77438  ? 200 ILE A N    1 
ATOM   2998 C CA   . ILE A 1 200 ? -22.96576 -12.11962 -13.46232 1.000 37.92706  ? 200 ILE A CA   1 
ATOM   2999 C C    . ILE A 1 200 ? -24.31148 -12.65843 -13.94434 1.000 36.62753  ? 200 ILE A C    1 
ATOM   3000 O O    . ILE A 1 200 ? -24.74494 -12.38168 -15.06323 1.000 30.64563  ? 200 ILE A O    1 
ATOM   3001 C CB   . ILE A 1 200 ? -22.74040 -10.66744 -13.88740 1.000 34.83865  ? 200 ILE A CB   1 
ATOM   3002 C CG1  . ILE A 1 200 ? -21.33539 -10.21221 -13.47352 1.000 32.29305  ? 200 ILE A CG1  1 
ATOM   3003 C CG2  . ILE A 1 200 ? -23.78986 -9.75725  -13.26321 1.000 33.81372  ? 200 ILE A CG2  1 
ATOM   3004 C CD1  . ILE A 1 200 ? -20.76877 -9.09225  -14.34153 1.000 37.56728  ? 200 ILE A CD1  1 
ATOM   3005 H H    . ILE A 1 200 ? -21.58825 -12.72441 -14.73364 1.000 52.52302  ? 200 ILE A H    1 
ATOM   3006 H HA   . ILE A 1 200 ? -22.95539 -12.15798 -12.49314 1.000 45.50624  ? 200 ILE A HA   1 
ATOM   3007 H HB   . ILE A 1 200 ? -22.82021 -10.61521 -14.85270 1.000 41.80015  ? 200 ILE A HB   1 
ATOM   3008 H HG12 . ILE A 1 200 ? -21.36919 -9.88946  -12.55941 1.000 38.74543  ? 200 ILE A HG12 1 
ATOM   3009 H HG13 . ILE A 1 200 ? -20.73174 -10.96891 -13.53607 1.000 38.74543  ? 200 ILE A HG13 1 
ATOM   3010 H HG21 . ILE A 1 200 ? -23.51544 -8.83394  -13.37766 1.000 40.57023  ? 200 ILE A HG21 1 
ATOM   3011 H HG22 . ILE A 1 200 ? -24.64045 -9.90670  -13.70486 1.000 40.57023  ? 200 ILE A HG22 1 
ATOM   3012 H HG23 . ILE A 1 200 ? -23.86652 -9.96490  -12.31880 1.000 40.57023  ? 200 ILE A HG23 1 
ATOM   3013 H HD11 . ILE A 1 200 ? -21.47869 -8.46549  -14.55148 1.000 45.07451  ? 200 ILE A HD11 1 
ATOM   3014 H HD12 . ILE A 1 200 ? -20.06262 -8.64077  -13.85325 1.000 45.07451  ? 200 ILE A HD12 1 
ATOM   3015 H HD13 . ILE A 1 200 ? -20.41322 -9.47520  -15.15875 1.000 45.07451  ? 200 ILE A HD13 1 
ATOM   3016 N N    . THR A 1 201 ? -24.98408 -13.42143 -13.07650 1.000 37.94712  ? 201 THR A N    1 
ATOM   3017 C CA   . THR A 1 201 ? -26.16047 -14.18611 -13.48742 1.000 33.44031  ? 201 THR A CA   1 
ATOM   3018 C C    . THR A 1 201 ? -27.28727 -13.28292 -13.97859 1.000 35.07118  ? 201 THR A C    1 
ATOM   3019 O O    . THR A 1 201 ? -27.90594 -13.55126 -15.01605 1.000 32.70263  ? 201 THR A O    1 
ATOM   3020 C CB   . THR A 1 201 ? -26.64862 -15.04595 -12.31959 1.000 45.82473  ? 201 THR A CB   1 
ATOM   3021 O OG1  . THR A 1 201 ? -25.56055 -15.82571 -11.80785 1.000 40.50752  ? 201 THR A OG1  1 
ATOM   3022 C CG2  . THR A 1 201 ? -27.77923 -15.96706 -12.76489 1.000 39.95447  ? 201 THR A CG2  1 
ATOM   3023 H H    . THR A 1 201 ? -24.77925 -13.51244 -12.24622 1.000 45.53032  ? 201 THR A H    1 
ATOM   3024 H HA   . THR A 1 201 ? -25.90389 -14.76449 -14.22263 1.000 40.12215  ? 201 THR A HA   1 
ATOM   3025 H HB   . THR A 1 201 ? -26.98887 -14.47247 -11.61513 1.000 54.98345  ? 201 THR A HB   1 
ATOM   3026 H HG1  . THR A 1 201 ? -24.99740 -15.32465 -11.43717 1.000 48.60280  ? 201 THR A HG1  1 
ATOM   3027 H HG21 . THR A 1 201 ? -27.65609 -16.21841 -13.69363 1.000 47.93914  ? 201 THR A HG21 1 
ATOM   3028 H HG22 . THR A 1 201 ? -27.78750 -16.76952 -12.22002 1.000 47.93914  ? 201 THR A HG22 1 
ATOM   3029 H HG23 . THR A 1 201 ? -28.63210 -15.51447 -12.67168 1.000 47.93914  ? 201 THR A HG23 1 
ATOM   3030 N N    . VAL A 1 202 ? -27.59012 -12.21939 -13.23050 1.000 30.51475  ? 202 VAL A N    1 
ATOM   3031 C CA   . VAL A 1 202 ? -28.72325 -11.37004 -13.58859 1.000 33.14647  ? 202 VAL A CA   1 
ATOM   3032 C C    . VAL A 1 202 ? -28.51530 -10.73590 -14.95915 1.000 34.62694  ? 202 VAL A C    1 
ATOM   3033 O O    . VAL A 1 202 ? -29.48437 -10.48119 -15.68551 1.000 33.70158  ? 202 VAL A O    1 
ATOM   3034 C CB   . VAL A 1 202 ? -28.96356 -10.30754 -12.49292 1.000 32.84217  ? 202 VAL A CB   1 
ATOM   3035 C CG1  . VAL A 1 202 ? -27.75199 -9.39049  -12.33756 1.000 35.95581  ? 202 VAL A CG1  1 
ATOM   3036 C CG2  . VAL A 1 202 ? -30.22178 -9.49887  -12.79869 1.000 36.79646  ? 202 VAL A CG2  1 
ATOM   3037 H H    . VAL A 1 202 ? -27.16343 -11.97383 -12.52534 1.000 36.61147  ? 202 VAL A H    1 
ATOM   3038 H HA   . VAL A 1 202 ? -29.51781 -11.92392 -13.64141 1.000 39.76953  ? 202 VAL A HA   1 
ATOM   3039 H HB   . VAL A 1 202 ? -29.09439 -10.76336 -11.64674 1.000 39.40437  ? 202 VAL A HB   1 
ATOM   3040 H HG11 . VAL A 1 202 ? -27.93885 -8.73446  -11.64792 1.000 43.14074  ? 202 VAL A HG11 1 
ATOM   3041 H HG12 . VAL A 1 202 ? -26.98202 -9.92431  -12.08638 1.000 43.14074  ? 202 VAL A HG12 1 
ATOM   3042 H HG13 . VAL A 1 202 ? -27.58360 -8.94390  -13.18201 1.000 43.14074  ? 202 VAL A HG13 1 
ATOM   3043 H HG21 . VAL A 1 202 ? -30.42712 -8.93424  -12.03716 1.000 44.14952  ? 202 VAL A HG21 1 
ATOM   3044 H HG22 . VAL A 1 202 ? -30.06225 -8.95108  -13.58315 1.000 44.14952  ? 202 VAL A HG22 1 
ATOM   3045 H HG23 . VAL A 1 202 ? -30.95682 -10.10943 -12.96552 1.000 44.14952  ? 202 VAL A HG23 1 
ATOM   3046 N N    . ASN A 1 203 ? -27.25974 -10.48159 -15.34229 1.000 35.89493  ? 203 ASN A N    1 
ATOM   3047 C CA   . ASN A 1 203 ? -26.98578 -9.93137  -16.66682 1.000 29.73365  ? 203 ASN A CA   1 
ATOM   3048 C C    . ASN A 1 203 ? -27.17036 -10.98826 -17.75087 1.000 31.41822  ? 203 ASN A C    1 
ATOM   3049 O O    . ASN A 1 203 ? -27.66264 -10.68632 -18.84470 1.000 28.22676  ? 203 ASN A O    1 
ATOM   3050 C CB   . ASN A 1 203 ? -25.56631 -9.36038  -16.71859 1.000 35.95559  ? 203 ASN A CB   1 
ATOM   3051 C CG   . ASN A 1 203 ? -25.37581 -8.16600  -15.79636 1.000 36.21640  ? 203 ASN A CG   1 
ATOM   3052 O OD1  . ASN A 1 203 ? -26.33947 -7.60697  -15.27299 1.000 41.29905  ? 203 ASN A OD1  1 
ATOM   3053 N ND2  . ASN A 1 203 ? -24.12475 -7.76386  -15.60312 1.000 37.24461  ? 203 ASN A ND2  1 
ATOM   3054 H H    . ASN A 1 203 ? -26.56082 -10.61737 -14.85993 1.000 43.06769  ? 203 ASN A H    1 
ATOM   3055 H HA   . ASN A 1 203 ? -27.60850 -9.20736  -16.83690 1.000 35.67416  ? 203 ASN A HA   1 
ATOM   3056 H HB2  . ASN A 1 203 ? -24.93884 -10.04948 -16.44968 1.000 43.14048  ? 203 ASN A HB2  1 
ATOM   3057 H HB3  . ASN A 1 203 ? -25.37468 -9.07255  -17.62486 1.000 43.14048  ? 203 ASN A HB3  1 
ATOM   3058 H HD21 . ASN A 1 203 ? -23.96319 -7.09268  -15.09026 1.000 44.68731  ? 203 ASN A HD21 1 
ATOM   3059 H HD22 . ASN A 1 203 ? -23.47629 -8.17465  -15.99086 1.000 44.68731  ? 203 ASN A HD22 1 
ATOM   3060 N N    . VAL A 1 204 ? -26.76265 -12.22990 -17.47522 1.000 35.18206  ? 204 VAL A N    1 
ATOM   3061 C CA   . VAL A 1 204 ? -27.01246 -13.31166 -18.42331 1.000 34.71010  ? 204 VAL A CA   1 
ATOM   3062 C C    . VAL A 1 204 ? -28.50749 -13.46444 -18.66640 1.000 34.69470  ? 204 VAL A C    1 
ATOM   3063 O O    . VAL A 1 204 ? -28.94665 -13.68408 -19.80115 1.000 38.66963  ? 204 VAL A O    1 
ATOM   3064 C CB   . VAL A 1 204 ? -26.38969 -14.62825 -17.92383 1.000 32.53335  ? 204 VAL A CB   1 
ATOM   3065 C CG1  . VAL A 1 204 ? -26.82758 -15.79494 -18.81363 1.000 33.62870  ? 204 VAL A CG1  1 
ATOM   3066 C CG2  . VAL A 1 204 ? -24.87593 -14.52158 -17.89519 1.000 32.57109  ? 204 VAL A CG2  1 
ATOM   3067 H H    . VAL A 1 204 ? -26.34762 -12.46590 -16.75992 1.000 42.21224  ? 204 VAL A H    1 
ATOM   3068 H HA   . VAL A 1 204 ? -26.58731 -13.08229 -19.26446 1.000 41.64589  ? 204 VAL A HA   1 
ATOM   3069 H HB   . VAL A 1 204 ? -26.69876 -14.80026 -17.02062 1.000 39.03380  ? 204 VAL A HB   1 
ATOM   3070 H HG11 . VAL A 1 204 ? -26.28795 -16.57287 -18.60263 1.000 40.34821  ? 204 VAL A HG11 1 
ATOM   3071 H HG12 . VAL A 1 204 ? -27.76358 -15.98621 -18.64566 1.000 40.34821  ? 204 VAL A HG12 1 
ATOM   3072 H HG13 . VAL A 1 204 ? -26.70214 -15.54758 -19.74314 1.000 40.34821  ? 204 VAL A HG13 1 
ATOM   3073 H HG21 . VAL A 1 204 ? -24.62161 -13.59732 -18.04339 1.000 39.07908  ? 204 VAL A HG21 1 
ATOM   3074 H HG22 . VAL A 1 204 ? -24.55477 -14.81826 -17.02931 1.000 39.07908  ? 204 VAL A HG22 1 
ATOM   3075 H HG23 . VAL A 1 204 ? -24.50652 -15.08259 -18.59498 1.000 39.07908  ? 204 VAL A HG23 1 
ATOM   3076 N N    . LEU A 1 205 ? -29.31276 -13.36061 -17.60514 1.000 33.97468  ? 205 LEU A N    1 
ATOM   3077 C CA   . LEU A 1 205 ? -30.76142 -13.43782 -17.76817 1.000 36.51473  ? 205 LEU A CA   1 
ATOM   3078 C C    . LEU A 1 205 ? -31.27953 -12.26062 -18.58436 1.000 33.03786  ? 205 LEU A C    1 
ATOM   3079 O O    . LEU A 1 205 ? -32.14879 -12.42826 -19.44800 1.000 36.06179  ? 205 LEU A O    1 
ATOM   3080 C CB   . LEU A 1 205 ? -31.44327 -13.49425 -16.39770 1.000 30.41474  ? 205 LEU A CB   1 
ATOM   3081 C CG   . LEU A 1 205 ? -31.09002 -14.72867 -15.55797 1.000 34.53315  ? 205 LEU A CG   1 
ATOM   3082 C CD1  . LEU A 1 205 ? -31.53139 -14.56899 -14.10543 1.000 41.49056  ? 205 LEU A CD1  1 
ATOM   3083 C CD2  . LEU A 1 205 ? -31.70091 -15.99590 -16.14976 1.000 38.91809  ? 205 LEU A CD2  1 
ATOM   3084 H H    . LEU A 1 205 ? -29.04828 -13.24705 -16.79474 1.000 40.76339  ? 205 LEU A H    1 
ATOM   3085 H HA   . LEU A 1 205 ? -30.98473 -14.25418 -18.24208 1.000 43.81145  ? 205 LEU A HA   1 
ATOM   3086 H HB2  . LEU A 1 205 ? -31.18063 -12.71006 -15.89078 1.000 36.49146  ? 205 LEU A HB2  1 
ATOM   3087 H HB3  . LEU A 1 205 ? -32.40395 -13.49619 -16.53180 1.000 36.49146  ? 205 LEU A HB3  1 
ATOM   3088 H HG   . LEU A 1 205 ? -30.12439 -14.81988 -15.56938 1.000 41.43355  ? 205 LEU A HG   1 
ATOM   3089 H HD11 . LEU A 1 205 ? -32.40934 -14.15702 -14.08561 1.000 49.78244  ? 205 LEU A HD11 1 
ATOM   3090 H HD12 . LEU A 1 205 ? -31.56708 -15.44394 -13.68821 1.000 49.78244  ? 205 LEU A HD12 1 
ATOM   3091 H HD13 . LEU A 1 205 ? -30.89169 -14.00689 -13.64096 1.000 49.78244  ? 205 LEU A HD13 1 
ATOM   3092 H HD21 . LEU A 1 205 ? -31.38009 -16.76368 -15.65126 1.000 46.69548  ? 205 LEU A HD21 1 
ATOM   3093 H HD22 . LEU A 1 205 ? -32.66720 -15.94027 -16.08584 1.000 46.69548  ? 205 LEU A HD22 1 
ATOM   3094 H HD23 . LEU A 1 205 ? -31.43465 -16.07041 -17.07952 1.000 46.69548  ? 205 LEU A HD23 1 
ATOM   3095 N N    . ALA A 1 206 ? -30.75342 -11.06041 -18.33024 1.000 32.16116  ? 206 ALA A N    1 
ATOM   3096 C CA   . ALA A 1 206 ? -31.13402 -9.90693  -19.13870 1.000 30.11428  ? 206 ALA A CA   1 
ATOM   3097 C C    . ALA A 1 206 ? -30.77907 -10.12879 -20.60418 1.000 35.48831  ? 206 ALA A C    1 
ATOM   3098 O O    . ALA A 1 206 ? -31.56830 -9.80945  -21.50218 1.000 29.29258  ? 206 ALA A O    1 
ATOM   3099 C CB   . ALA A 1 206 ? -30.45135 -8.64824  -18.60356 1.000 24.62034  ? 206 ALA A CB   1 
ATOM   3100 H H    . ALA A 1 206 ? -30.18508 -10.89210 -17.70714 1.000 38.58716  ? 206 ALA A H    1 
ATOM   3101 H HA   . ALA A 1 206 ? -32.09328 -9.77725  -19.07630 1.000 36.13091  ? 206 ALA A HA   1 
ATOM   3102 H HB1  . ALA A 1 206 ? -30.69098 -8.53125  -17.67094 1.000 29.53818  ? 206 ALA A HB1  1 
ATOM   3103 H HB2  . ALA A 1 206 ? -29.49040 -8.75004  -18.68792 1.000 29.53818  ? 206 ALA A HB2  1 
ATOM   3104 H HB3  . ALA A 1 206 ? -30.74956 -7.88333  -19.12017 1.000 29.53818  ? 206 ALA A HB3  1 
ATOM   3105 N N    . TRP A 1 207 ? -29.59550 -10.68730 -20.86108 1.000 35.98407  ? 207 TRP A N    1 
ATOM   3106 C CA   . TRP A 1 207 ? -29.15997 -10.93638 -22.23083 1.000 36.05952  ? 207 TRP A CA   1 
ATOM   3107 C C    . TRP A 1 207 ? -30.03873 -11.98302 -22.90175 1.000 32.20066  ? 207 TRP A C    1 
ATOM   3108 O O    . TRP A 1 207 ? -30.34875 -11.87241 -24.09415 1.000 32.81845  ? 207 TRP A O    1 
ATOM   3109 C CB   . TRP A 1 207 ? -27.69351 -11.36534 -22.21329 1.000 36.56931  ? 207 TRP A CB   1 
ATOM   3110 C CG   . TRP A 1 207 ? -27.11531 -11.71390 -23.53590 1.000 40.50556  ? 207 TRP A CG   1 
ATOM   3111 C CD1  . TRP A 1 207 ? -26.81441 -10.85683 -24.54983 1.000 37.62179  ? 207 TRP A CD1  1 
ATOM   3112 C CD2  . TRP A 1 207 ? -26.73595 -13.01959 -23.98472 1.000 39.36046  ? 207 TRP A CD2  1 
ATOM   3113 N NE1  . TRP A 1 207 ? -26.27787 -11.54798 -25.60838 1.000 43.86405  ? 207 TRP A NE1  1 
ATOM   3114 C CE2  . TRP A 1 207 ? -26.22045 -12.87871 -25.28671 1.000 43.83799  ? 207 TRP A CE2  1 
ATOM   3115 C CE3  . TRP A 1 207 ? -26.78640 -14.29466 -23.41306 1.000 43.73819  ? 207 TRP A CE3  1 
ATOM   3116 C CZ2  . TRP A 1 207 ? -25.75839 -13.96369 -26.02817 1.000 45.33296  ? 207 TRP A CZ2  1 
ATOM   3117 C CZ3  . TRP A 1 207 ? -26.32686 -15.37253 -24.15193 1.000 45.39861  ? 207 TRP A CZ3  1 
ATOM   3118 C CH2  . TRP A 1 207 ? -25.81696 -15.19866 -25.44356 1.000 41.51773  ? 207 TRP A CH2  1 
ATOM   3119 H H    . TRP A 1 207 ? -29.02874 -10.93006 -20.26154 1.000 43.17466  ? 207 TRP A H    1 
ATOM   3120 H HA   . TRP A 1 207 ? -29.23104 -10.12359 -22.75545 1.000 43.26520  ? 207 TRP A HA   1 
ATOM   3121 H HB2  . TRP A 1 207 ? -27.16632 -10.63631 -21.85067 1.000 43.87695  ? 207 TRP A HB2  1 
ATOM   3122 H HB3  . TRP A 1 207 ? -27.61103 -12.14826 -21.64662 1.000 43.87695  ? 207 TRP A HB3  1 
ATOM   3123 H HD1  . TRP A 1 207 ? -26.95211 -9.93733  -24.52876 1.000 45.13992  ? 207 TRP A HD1  1 
ATOM   3124 H HE1  . TRP A 1 207 ? -26.01988 -11.20187 -26.35219 1.000 52.63063  ? 207 TRP A HE1  1 
ATOM   3125 H HE3  . TRP A 1 207 ? -27.12168 -14.41661 -22.55422 1.000 52.47960  ? 207 TRP A HE3  1 
ATOM   3126 H HZ2  . TRP A 1 207 ? -25.42273 -13.85244 -26.88832 1.000 54.39332  ? 207 TRP A HZ2  1 
ATOM   3127 H HZ3  . TRP A 1 207 ? -26.35771 -16.22590 -23.78353 1.000 54.47210  ? 207 TRP A HZ3  1 
ATOM   3128 H HH2  . TRP A 1 207 ? -25.51103 -15.93965 -25.91498 1.000 49.81504  ? 207 TRP A HH2  1 
ATOM   3129 N N    . LEU A 1 208 ? -30.45559 -13.00289 -22.14875 1.000 34.16558  ? 208 LEU A N    1 
ATOM   3130 C CA   . LEU A 1 208 ? -31.39937 -13.97918 -22.68074 1.000 36.64102  ? 208 LEU A CA   1 
ATOM   3131 C C    . LEU A 1 208 ? -32.74393 -13.34056 -23.00643 1.000 37.60138  ? 208 LEU A C    1 
ATOM   3132 O O    . LEU A 1 208 ? -33.43746 -13.79444 -23.92377 1.000 37.59224  ? 208 LEU A O    1 
ATOM   3133 C CB   . LEU A 1 208 ? -31.58545 -15.12226 -21.68434 1.000 34.82140  ? 208 LEU A CB   1 
ATOM   3134 C CG   . LEU A 1 208 ? -30.37163 -16.02882 -21.47953 1.000 30.21587  ? 208 LEU A CG   1 
ATOM   3135 C CD1  . LEU A 1 208 ? -30.65185 -17.03968 -20.38393 1.000 31.41574  ? 208 LEU A CD1  1 
ATOM   3136 C CD2  . LEU A 1 208 ? -29.99246 -16.72911 -22.78015 1.000 31.87751  ? 208 LEU A CD2  1 
ATOM   3137 H H    . LEU A 1 208 ? -30.20943 -13.14877 -21.33775 1.000 40.99247  ? 208 LEU A H    1 
ATOM   3138 H HA   . LEU A 1 208 ? -31.03635 -14.34877 -23.50081 1.000 43.96300  ? 208 LEU A HA   1 
ATOM   3139 H HB2  . LEU A 1 208 ? -31.80814 -14.73931 -20.82140 1.000 41.77945  ? 208 LEU A HB2  1 
ATOM   3140 H HB3  . LEU A 1 208 ? -32.31363 -15.68169 -21.99691 1.000 41.77945  ? 208 LEU A HB3  1 
ATOM   3141 H HG   . LEU A 1 208 ? -29.61387 -15.48826 -21.20662 1.000 36.25281  ? 208 LEU A HG   1 
ATOM   3142 H HD11 . LEU A 1 208 ? -31.40685 -17.58907 -20.64672 1.000 37.69266  ? 208 LEU A HD11 1 
ATOM   3143 H HD12 . LEU A 1 208 ? -29.86653 -17.59501 -20.25824 1.000 37.69266  ? 208 LEU A HD12 1 
ATOM   3144 H HD13 . LEU A 1 208 ? -30.85719 -16.56636 -19.56253 1.000 37.69266  ? 208 LEU A HD13 1 
ATOM   3145 H HD21 . LEU A 1 208 ? -30.77752 -16.78983 -23.34662 1.000 38.24678  ? 208 LEU A HD21 1 
ATOM   3146 H HD22 . LEU A 1 208 ? -29.30173 -16.21447 -23.22617 1.000 38.24678  ? 208 LEU A HD22 1 
ATOM   3147 H HD23 . LEU A 1 208 ? -29.66258 -17.61807 -22.57564 1.000 38.24678  ? 208 LEU A HD23 1 
ATOM   3148 N N    . TYR A 1 209 ? -33.13662 -12.30094 -22.26357 1.000 36.41074  ? 209 TYR A N    1 
ATOM   3149 C CA   . TYR A 1 209 ? -34.35744 -11.57416 -22.60034 1.000 35.84565  ? 209 TYR A CA   1 
ATOM   3150 C C    . TYR A 1 209 ? -34.16569 -10.72248 -23.85034 1.000 36.83128  ? 209 TYR A C    1 
ATOM   3151 O O    . TYR A 1 209 ? -35.09442 -10.56550 -24.65203 1.000 36.71812  ? 209 TYR A O    1 
ATOM   3152 C CB   . TYR A 1 209 ? -34.79423 -10.70117 -21.42406 1.000 38.81338  ? 209 TYR A CB   1 
ATOM   3153 C CG   . TYR A 1 209 ? -35.62292 -11.43292 -20.39306 1.000 37.60333  ? 209 TYR A CG   1 
ATOM   3154 C CD1  . TYR A 1 209 ? -36.91438 -11.85022 -20.68402 1.000 43.58713  ? 209 TYR A CD1  1 
ATOM   3155 C CD2  . TYR A 1 209 ? -35.11894 -11.69908 -19.12918 1.000 33.99125  ? 209 TYR A CD2  1 
ATOM   3156 C CE1  . TYR A 1 209 ? -37.67835 -12.51915 -19.74728 1.000 38.37665  ? 209 TYR A CE1  1 
ATOM   3157 C CE2  . TYR A 1 209 ? -35.87578 -12.36267 -18.18396 1.000 46.45296  ? 209 TYR A CE2  1 
ATOM   3158 C CZ   . TYR A 1 209 ? -37.15464 -12.77055 -18.49775 1.000 44.25393  ? 209 TYR A CZ   1 
ATOM   3159 O OH   . TYR A 1 209 ? -37.90626 -13.43592 -17.55667 1.000 45.31857  ? 209 TYR A OH   1 
ATOM   3160 H H    . TYR A 1 209 ? -32.72026 -12.00325 -21.57247 1.000 43.68666  ? 209 TYR A H    1 
ATOM   3161 H HA   . TYR A 1 209 ? -35.06217 -12.21721 -22.77566 1.000 43.00855  ? 209 TYR A HA   1 
ATOM   3162 H HB2  . TYR A 1 209 ? -34.00286 -10.35982 -20.97896 1.000 46.56983  ? 209 TYR A HB2  1 
ATOM   3163 H HB3  . TYR A 1 209 ? -35.32732 -9.96533  -21.76356 1.000 46.56983  ? 209 TYR A HB3  1 
ATOM   3164 H HD1  . TYR A 1 209 ? -37.27186 -11.67636 -21.52478 1.000 52.29833  ? 209 TYR A HD1  1 
ATOM   3165 H HD2  . TYR A 1 209 ? -34.25629 -11.42598 -18.91433 1.000 40.78327  ? 209 TYR A HD2  1 
ATOM   3166 H HE1  . TYR A 1 209 ? -38.54009 -12.79784 -19.95853 1.000 46.04575  ? 209 TYR A HE1  1 
ATOM   3167 H HE2  . TYR A 1 209 ? -35.52456 -12.53356 -17.33995 1.000 55.73733  ? 209 TYR A HE2  1 
ATOM   3168 H HH   . TYR A 1 209 ? -37.63320 -13.24715 -16.78505 1.000 54.37605  ? 209 TYR A HH   1 
ATOM   3169 N N    . ALA A 1 210 ? -32.97683 -10.14231 -24.02173 1.000 39.78971  ? 210 ALA A N    1 
ATOM   3170 C CA   . ALA A 1 210 ? -32.68191 -9.43836  -25.26371 1.000 45.27447  ? 210 ALA A CA   1 
ATOM   3171 C C    . ALA A 1 210 ? -32.78119 -10.38014 -26.45513 1.000 40.28249  ? 210 ALA A C    1 
ATOM   3172 O O    . ALA A 1 210 ? -33.28390 -9.99967  -27.51918 1.000 42.89679  ? 210 ALA A O    1 
ATOM   3173 C CB   . ALA A 1 210 ? -31.29064 -8.81133  -25.19647 1.000 39.36910  ? 210 ALA A CB   1 
ATOM   3174 H H    . ALA A 1 210 ? -32.33836 -10.14273 -23.44558 1.000 47.74143  ? 210 ALA A H    1 
ATOM   3175 H HA   . ALA A 1 210 ? -33.32688 -8.72345  -25.38129 1.000 54.32314  ? 210 ALA A HA   1 
ATOM   3176 H HB1  . ALA A 1 210 ? -30.63427 -9.51277  -25.06207 1.000 47.23669  ? 210 ALA A HB1  1 
ATOM   3177 H HB2  . ALA A 1 210 ? -31.11285 -8.34714  -26.02944 1.000 47.23669  ? 210 ALA A HB2  1 
ATOM   3178 H HB3  . ALA A 1 210 ? -31.26189 -8.18516  -24.45621 1.000 47.23669  ? 210 ALA A HB3  1 
ATOM   3179 N N    . ALA A 1 211 ? -32.30372 -11.61700 -26.29239 1.000 41.57440  ? 211 ALA A N    1 
ATOM   3180 C CA   . ALA A 1 211 ? -32.36400 -12.59022 -27.37727 1.000 37.89050  ? 211 ALA A CA   1 
ATOM   3181 C C    . ALA A 1 211 ? -33.80487 -12.88580 -27.76662 1.000 39.44272  ? 211 ALA A C    1 
ATOM   3182 O O    . ALA A 1 211 ? -34.16789 -12.81901 -28.94633 1.000 36.54374  ? 211 ALA A O    1 
ATOM   3183 C CB   . ALA A 1 211 ? -31.64776 -13.87641 -26.96630 1.000 31.49085  ? 211 ALA A CB   1 
ATOM   3184 H H    . ALA A 1 211 ? -31.94373 -11.91269 -25.56950 1.000 49.88305  ? 211 ALA A H    1 
ATOM   3185 H HA   . ALA A 1 211 ? -31.90899 -12.22299 -28.15122 1.000 45.46237  ? 211 ALA A HA   1 
ATOM   3186 H HB1  . ALA A 1 211 ? -30.74979 -13.86882 -27.33303 1.000 37.78279  ? 211 ALA A HB1  1 
ATOM   3187 H HB2  . ALA A 1 211 ? -31.60928 -13.92090 -25.99809 1.000 37.78279  ? 211 ALA A HB2  1 
ATOM   3188 H HB3  . ALA A 1 211 ? -32.14026 -14.63675 -27.31306 1.000 37.78279  ? 211 ALA A HB3  1 
ATOM   3189 N N    . VAL A 1 212 ? -34.64249 -13.22186 -26.78311 1.000 41.69651  ? 212 VAL A N    1 
ATOM   3190 C CA   . VAL A 1 212 ? -36.03966 -13.52717 -27.07412 1.000 41.18016  ? 212 VAL A CA   1 
ATOM   3191 C C    . VAL A 1 212 ? -36.70245 -12.34871 -27.77342 1.000 30.82354  ? 212 VAL A C    1 
ATOM   3192 O O    . VAL A 1 212 ? -37.41700 -12.52120 -28.76687 1.000 35.31702  ? 212 VAL A O    1 
ATOM   3193 C CB   . VAL A 1 212 ? -36.78195 -13.91841 -25.78224 1.000 41.42398  ? 212 VAL A CB   1 
ATOM   3194 C CG1  . VAL A 1 212 ? -38.27315 -14.08276 -26.04908 1.000 36.23439  ? 212 VAL A CG1  1 
ATOM   3195 C CG2  . VAL A 1 212 ? -36.19276 -15.20181 -25.20242 1.000 35.14271  ? 212 VAL A CG2  1 
ATOM   3196 H H    . VAL A 1 212 ? -34.42858 -13.27903 -25.95210 1.000 50.02958  ? 212 VAL A H    1 
ATOM   3197 H HA   . VAL A 1 212 ? -36.07300 -14.28729 -27.67579 1.000 49.40996  ? 212 VAL A HA   1 
ATOM   3198 H HB   . VAL A 1 212 ? -36.67206 -13.21029 -25.12848 1.000 49.70254  ? 212 VAL A HB   1 
ATOM   3199 H HG11 . VAL A 1 212 ? -38.66199 -14.62533 -25.34529 1.000 43.47503  ? 212 VAL A HG11 1 
ATOM   3200 H HG12 . VAL A 1 212 ? -38.69033 -13.20713 -26.06041 1.000 43.47503  ? 212 VAL A HG12 1 
ATOM   3201 H HG13 . VAL A 1 212 ? -38.39428 -14.51800 -26.90744 1.000 43.47503  ? 212 VAL A HG13 1 
ATOM   3202 H HG21 . VAL A 1 212 ? -36.62582 -15.39384 -24.35597 1.000 42.16502  ? 212 VAL A HG21 1 
ATOM   3203 H HG22 . VAL A 1 212 ? -36.34651 -15.92940 -25.82521 1.000 42.16502  ? 212 VAL A HG22 1 
ATOM   3204 H HG23 . VAL A 1 212 ? -35.24030 -15.07866 -25.06624 1.000 42.16502  ? 212 VAL A HG23 1 
ATOM   3205 N N    . ILE A 1 213 ? -36.45924 -11.13117 -27.28722 1.000 38.99952  ? 213 ILE A N    1 
ATOM   3206 C CA   . ILE A 1 213 ? -37.05768 -9.96381  -27.92547 1.000 40.23465  ? 213 ILE A CA   1 
ATOM   3207 C C    . ILE A 1 213 ? -36.65988 -9.89204  -29.39444 1.000 41.49456  ? 213 ILE A C    1 
ATOM   3208 O O    . ILE A 1 213 ? -37.44847 -9.44473  -30.23633 1.000 46.57585  ? 213 ILE A O    1 
ATOM   3209 C CB   . ILE A 1 213 ? -36.66672 -8.68451  -27.16009 1.000 40.64177  ? 213 ILE A CB   1 
ATOM   3210 C CG1  . ILE A 1 213 ? -37.40190 -8.62762  -25.81797 1.000 46.09575  ? 213 ILE A CG1  1 
ATOM   3211 C CG2  . ILE A 1 213 ? -36.97781 -7.45599  -27.99042 1.000 44.80609  ? 213 ILE A CG2  1 
ATOM   3212 C CD1  . ILE A 1 213 ? -36.82706 -7.62258  -24.84230 1.000 43.06577  ? 213 ILE A CD1  1 
ATOM   3213 H H    . ILE A 1 213 ? -35.96347 -10.95943 -26.60582 1.000 46.79319  ? 213 ILE A H    1 
ATOM   3214 H HA   . ILE A 1 213 ? -38.02336 -10.04718 -27.88783 1.000 48.27535  ? 213 ILE A HA   1 
ATOM   3215 H HB   . ILE A 1 213 ? -35.71207 -8.70579  -26.98957 1.000 48.76390  ? 213 ILE A HB   1 
ATOM   3216 H HG12 . ILE A 1 213 ? -38.32698 -8.38519  -25.98032 1.000 55.30868  ? 213 ILE A HG12 1 
ATOM   3217 H HG13 . ILE A 1 213 ? -37.35640 -9.50239  -25.40131 1.000 55.30868  ? 213 ILE A HG13 1 
ATOM   3218 H HG21 . ILE A 1 213 ? -37.84709 -7.56759  -28.40610 1.000 53.76108  ? 213 ILE A HG21 1 
ATOM   3219 H HG22 . ILE A 1 213 ? -36.98530 -6.67742  -27.41191 1.000 53.76108  ? 213 ILE A HG22 1 
ATOM   3220 H HG23 . ILE A 1 213 ? -36.29556 -7.35475  -28.67246 1.000 53.76108  ? 213 ILE A HG23 1 
ATOM   3221 H HD11 . ILE A 1 213 ? -37.39067 -7.59020  -24.05351 1.000 51.67270  ? 213 ILE A HD11 1 
ATOM   3222 H HD12 . ILE A 1 213 ? -35.93003 -7.89821  -24.59681 1.000 51.67270  ? 213 ILE A HD12 1 
ATOM   3223 H HD13 . ILE A 1 213 ? -36.80078 -6.75045  -25.26610 1.000 51.67270  ? 213 ILE A HD13 1 
ATOM   3224 N N    . ASN A 1 214 ? -35.45829 -10.36035 -29.73327 1.000 47.45147  ? 214 ASN A N    1 
ATOM   3225 C CA   . ASN A 1 214 ? -34.94141 -10.29230 -31.09479 1.000 37.75684  ? 214 ASN A CA   1 
ATOM   3226 C C    . ASN A 1 214 ? -35.18724 -11.56227 -31.90355 1.000 37.33485  ? 214 ASN A C    1 
ATOM   3227 O O    . ASN A 1 214 ? -34.74674 -11.63584 -33.05593 1.000 42.99320  ? 214 ASN A O    1 
ATOM   3228 C CB   . ASN A 1 214 ? -33.44264 -9.97680  -31.06164 1.000 45.50471  ? 214 ASN A CB   1 
ATOM   3229 C CG   . ASN A 1 214 ? -33.16601 -8.49874  -30.83586 1.000 53.62317  ? 214 ASN A CG   1 
ATOM   3230 O OD1  . ASN A 1 214 ? -32.90645 -7.75438  -31.78339 1.000 51.10174  ? 214 ASN A OD1  1 
ATOM   3231 N ND2  . ASN A 1 214 ? -33.23787 -8.06321  -29.57823 1.000 46.74851  ? 214 ASN A ND2  1 
ATOM   3232 H H    . ASN A 1 214 ? -34.91437 -10.72928 -29.17862 1.000 56.93554  ? 214 ASN A H    1 
ATOM   3233 H HA   . ASN A 1 214 ? -35.39210 -9.57014  -31.55984 1.000 45.30197  ? 214 ASN A HA   1 
ATOM   3234 H HB2  . ASN A 1 214 ? -33.02941 -10.47458 -30.33890 1.000 54.59942  ? 214 ASN A HB2  1 
ATOM   3235 H HB3  . ASN A 1 214 ? -33.04582 -10.23163 -31.90928 1.000 54.59942  ? 214 ASN A HB3  1 
ATOM   3236 H HD21 . ASN A 1 214 ? -33.08939 -7.23490  -29.40088 1.000 56.09199  ? 214 ASN A HD21 1 
ATOM   3237 H HD22 . ASN A 1 214 ? -33.43272 -8.61051  -28.94411 1.000 56.09199  ? 214 ASN A HD22 1 
ATOM   3238 N N    . GLY A 1 215 ? -35.88227 -12.55264 -31.34607 1.000 38.22746  ? 215 GLY A N    1 
ATOM   3239 C CA   . GLY A 1 215 ? -36.30603 -13.71988 -32.09571 1.000 39.93921  ? 215 GLY A CA   1 
ATOM   3240 C C    . GLY A 1 215 ? -35.55823 -14.99717 -31.78178 1.000 46.42752  ? 215 GLY A C    1 
ATOM   3241 O O    . GLY A 1 215 ? -35.99204 -16.06830 -32.22675 1.000 45.16099  ? 215 GLY A O    1 
ATOM   3242 H H    . GLY A 1 215 ? -36.12163 -12.56593 -30.52015 1.000 45.86672  ? 215 GLY A H    1 
ATOM   3243 H HA2  . GLY A 1 215 ? -37.24597 -13.87809 -31.91574 1.000 47.92083  ? 215 GLY A HA2  1 
ATOM   3244 H HA3  . GLY A 1 215 ? -36.19191 -13.53770 -33.04159 1.000 47.92083  ? 215 GLY A HA3  1 
ATOM   3245 N N    . ASP A 1 216 ? -34.45035 -14.92828 -31.04636 1.000 42.76074  ? 216 ASP A N    1 
ATOM   3246 C CA   . ASP A 1 216 ? -33.71597 -16.12402 -30.64179 1.000 46.75017  ? 216 ASP A CA   1 
ATOM   3247 C C    . ASP A 1 216 ? -34.44213 -16.79578 -29.48374 1.000 49.29935  ? 216 ASP A C    1 
ATOM   3248 O O    . ASP A 1 216 ? -34.37849 -16.32235 -28.34450 1.000 53.57795  ? 216 ASP A O    1 
ATOM   3249 C CB   . ASP A 1 216 ? -32.28898 -15.76016 -30.24972 1.000 42.61926  ? 216 ASP A CB   1 
ATOM   3250 C CG   . ASP A 1 216 ? -31.33928 -15.81913 -31.41827 1.000 54.79894  ? 216 ASP A CG   1 
ATOM   3251 O OD1  . ASP A 1 216 ? -31.07422 -16.93863 -31.90704 1.000 62.51206  ? 216 ASP A OD1  1 
ATOM   3252 O OD2  . ASP A 1 216 ? -30.87356 -14.74725 -31.85865 1.000 65.61027  ? 216 ASP A OD2  1 
ATOM   3253 H H    . ASP A 1 216 ? -34.10097 -14.19384 -30.76683 1.000 51.30665  ? 216 ASP A H    1 
ATOM   3254 H HA   . ASP A 1 216 ? -33.68630 -16.74562 -31.38585 1.000 56.09398  ? 216 ASP A HA   1 
ATOM   3255 H HB2  . ASP A 1 216 ? -32.27727 -14.85659 -29.89712 1.000 51.13688  ? 216 ASP A HB2  1 
ATOM   3256 H HB3  . ASP A 1 216 ? -31.97631 -16.38347 -29.57547 1.000 51.13688  ? 216 ASP A HB3  1 
ATOM   3257 N N    . ARG A 1 217 ? -35.11286 -17.91585 -29.76637 1.000 52.74586  ? 217 ARG A N    1 
ATOM   3258 C CA   . ARG A 1 217 ? -35.93145 -18.58911 -28.77029 1.000 51.24416  ? 217 ARG A CA   1 
ATOM   3259 C C    . ARG A 1 217 ? -35.59472 -20.06247 -28.57338 1.000 51.58650  ? 217 ARG A C    1 
ATOM   3260 O O    . ARG A 1 217 ? -36.16996 -20.68873 -27.67610 1.000 49.14942  ? 217 ARG A O    1 
ATOM   3261 C CB   . ARG A 1 217 ? -37.41997 -18.46604 -29.14034 1.000 46.82574  ? 217 ARG A CB   1 
ATOM   3262 H H    . ARG A 1 217 ? -35.10630 -18.30345 -30.53404 1.000 63.28881  ? 217 ARG A H    1 
ATOM   3263 H HA   . ARG A 1 217 ? -35.78752 -18.14773 -27.91860 1.000 61.48676  ? 217 ARG A HA   1 
ATOM   3264 N N    . TRP A 1 218 ? -34.66908 -20.62804 -29.35779 1.000 52.92352  ? 218 TRP A N    1 
ATOM   3265 C CA   . TRP A 1 218 ? -34.43470 -22.06997 -29.32422 1.000 40.94851  ? 218 TRP A CA   1 
ATOM   3266 C C    . TRP A 1 218 ? -34.07962 -22.58396 -27.93380 1.000 45.12533  ? 218 TRP A C    1 
ATOM   3267 O O    . TRP A 1 218 ? -34.15006 -23.79591 -27.69976 1.000 51.64599  ? 218 TRP A O    1 
ATOM   3268 C CB   . TRP A 1 218 ? -33.32029 -22.45620 -30.30756 1.000 48.12476  ? 218 TRP A CB   1 
ATOM   3269 C CG   . TRP A 1 218 ? -31.95137 -21.93565 -29.94768 1.000 44.23098  ? 218 TRP A CG   1 
ATOM   3270 C CD1  . TRP A 1 218 ? -31.34261 -20.81918 -30.44639 1.000 40.49209  ? 218 TRP A CD1  1 
ATOM   3271 C CD2  . TRP A 1 218 ? -31.02155 -22.51727 -29.02142 1.000 40.96889  ? 218 TRP A CD2  1 
ATOM   3272 N NE1  . TRP A 1 218 ? -30.09673 -20.66855 -29.88711 1.000 40.62646  ? 218 TRP A NE1  1 
ATOM   3273 C CE2  . TRP A 1 218 ? -29.87594 -21.69614 -29.00887 1.000 38.90199  ? 218 TRP A CE2  1 
ATOM   3274 C CE3  . TRP A 1 218 ? -31.04793 -23.64904 -28.20035 1.000 46.41740  ? 218 TRP A CE3  1 
ATOM   3275 C CZ2  . TRP A 1 218 ? -28.76978 -21.96828 -28.20733 1.000 42.69133  ? 218 TRP A CZ2  1 
ATOM   3276 C CZ3  . TRP A 1 218 ? -29.94562 -23.91801 -27.40461 1.000 47.98673  ? 218 TRP A CZ3  1 
ATOM   3277 C CH2  . TRP A 1 218 ? -28.82293 -23.08057 -27.41470 1.000 40.28075  ? 218 TRP A CH2  1 
ATOM   3278 H H    . TRP A 1 218 ? -34.16949 -20.20061 -29.91215 1.000 63.50199  ? 218 TRP A H    1 
ATOM   3279 H HA   . TRP A 1 218 ? -35.25479 -22.50654 -29.60305 1.000 49.13199  ? 218 TRP A HA   1 
ATOM   3280 H HB2  . TRP A 1 218 ? -33.26388 -23.42386 -30.34450 1.000 57.74348  ? 218 TRP A HB2  1 
ATOM   3281 H HB3  . TRP A 1 218 ? -33.54570 -22.10337 -31.18254 1.000 57.74348  ? 218 TRP A HB3  1 
ATOM   3282 H HD1  . TRP A 1 218 ? -31.71733 -20.24406 -31.07386 1.000 48.58428  ? 218 TRP A HD1  1 
ATOM   3283 H HE1  . TRP A 1 218 ? -29.54488 -20.03213 -30.06042 1.000 48.74552  ? 218 TRP A HE1  1 
ATOM   3284 H HE3  . TRP A 1 218 ? -31.78989 -24.20962 -28.18856 1.000 55.69465  ? 218 TRP A HE3  1 
ATOM   3285 H HZ2  . TRP A 1 218 ? -28.02305 -21.41397 -28.21131 1.000 51.22337  ? 218 TRP A HZ2  1 
ATOM   3286 H HZ3  . TRP A 1 218 ? -29.95144 -24.66768 -26.85428 1.000 57.57784  ? 218 TRP A HZ3  1 
ATOM   3287 H HH2  . TRP A 1 218 ? -28.09761 -23.28587 -26.87004 1.000 48.33068  ? 218 TRP A HH2  1 
ATOM   3288 N N    . PHE A 1 219 ? -33.70578 -21.70231 -27.00769 1.000 47.50339  ? 219 PHE A N    1 
ATOM   3289 C CA   . PHE A 1 219 ? -33.29269 -22.12177 -25.67496 1.000 43.88003  ? 219 PHE A CA   1 
ATOM   3290 C C    . PHE A 1 219 ? -34.43766 -22.14742 -24.66829 1.000 41.14468  ? 219 PHE A C    1 
ATOM   3291 O O    . PHE A 1 219 ? -34.27079 -22.71429 -23.58304 1.000 43.66955  ? 219 PHE A O    1 
ATOM   3292 C CB   . PHE A 1 219 ? -32.17274 -21.20544 -25.15375 1.000 47.47298  ? 219 PHE A CB   1 
ATOM   3293 C CG   . PHE A 1 219 ? -32.51169 -19.74497 -25.20186 1.000 37.72610  ? 219 PHE A CG   1 
ATOM   3294 C CD1  . PHE A 1 219 ? -33.16017 -19.13447 -24.14241 1.000 37.47413  ? 219 PHE A CD1  1 
ATOM   3295 C CD2  . PHE A 1 219 ? -32.18376 -18.98324 -26.31209 1.000 43.85727  ? 219 PHE A CD2  1 
ATOM   3296 C CE1  . PHE A 1 219 ? -33.47528 -17.78697 -24.18974 1.000 46.52740  ? 219 PHE A CE1  1 
ATOM   3297 C CE2  . PHE A 1 219 ? -32.49541 -17.64049 -26.36726 1.000 41.56196  ? 219 PHE A CE2  1 
ATOM   3298 C CZ   . PHE A 1 219 ? -33.14392 -17.04058 -25.30592 1.000 45.89405  ? 219 PHE A CZ   1 
ATOM   3299 H H    . PHE A 1 219 ? -33.68361 -20.85135 -27.13004 1.000 56.99783  ? 219 PHE A H    1 
ATOM   3300 H HA   . PHE A 1 219 ? -32.93656 -23.02209 -25.73406 1.000 52.64980  ? 219 PHE A HA   1 
ATOM   3301 H HB2  . PHE A 1 219 ? -31.98678 -21.43543 -24.22994 1.000 56.96135  ? 219 PHE A HB2  1 
ATOM   3302 H HB3  . PHE A 1 219 ? -31.38021 -21.34295 -25.69586 1.000 56.96135  ? 219 PHE A HB3  1 
ATOM   3303 H HD1  . PHE A 1 219 ? -33.38648 -19.63417 -23.39142 1.000 44.96272  ? 219 PHE A HD1  1 
ATOM   3304 H HD2  . PHE A 1 219 ? -31.74763 -19.38270 -27.02981 1.000 52.62250  ? 219 PHE A HD2  1 
ATOM   3305 H HE1  . PHE A 1 219 ? -33.90898 -17.38454 -23.47221 1.000 55.82665  ? 219 PHE A HE1  1 
ATOM   3306 H HE2  . PHE A 1 219 ? -32.26915 -17.14022 -27.11788 1.000 49.86812  ? 219 PHE A HE2  1 
ATOM   3307 H HZ   . PHE A 1 219 ? -33.35750 -16.13614 -25.34164 1.000 55.06663  ? 219 PHE A HZ   1 
ATOM   3308 N N    . LEU A 1 220 ? -35.58623 -21.55581 -24.98905 1.000 39.02088  ? 220 LEU A N    1 
ATOM   3309 C CA   . LEU A 1 220 ? -36.72536 -21.60240 -24.07974 1.000 50.57815  ? 220 LEU A CA   1 
ATOM   3310 C C    . LEU A 1 220 ? -37.23183 -23.03573 -23.95343 1.000 51.91928  ? 220 LEU A C    1 
ATOM   3311 O O    . LEU A 1 220 ? -37.51760 -23.69458 -24.95817 1.000 53.74045  ? 220 LEU A O    1 
ATOM   3312 C CB   . LEU A 1 220 ? -37.84271 -20.68335 -24.57621 1.000 48.12171  ? 220 LEU A CB   1 
ATOM   3313 C CG   . LEU A 1 220 ? -37.48532 -19.19706 -24.67439 1.000 45.48333  ? 220 LEU A CG   1 
ATOM   3314 C CD1  . LEU A 1 220 ? -38.53627 -18.42871 -25.46125 1.000 48.98866  ? 220 LEU A CD1  1 
ATOM   3315 C CD2  . LEU A 1 220 ? -37.30834 -18.59065 -23.28911 1.000 48.77798  ? 220 LEU A CD2  1 
ATOM   3316 H H    . LEU A 1 220 ? -35.72943 -21.12561 -25.71982 1.000 46.81883  ? 220 LEU A H    1 
ATOM   3317 H HA   . LEU A 1 220 ? -36.45205 -21.29307 -23.20195 1.000 60.68755  ? 220 LEU A HA   1 
ATOM   3318 H HB2  . LEU A 1 220 ? -38.10526 -20.97619 -25.46289 1.000 57.73983  ? 220 LEU A HB2  1 
ATOM   3319 H HB3  . LEU A 1 220 ? -38.59269 -20.76009 -23.96585 1.000 57.73983  ? 220 LEU A HB3  1 
ATOM   3320 H HG   . LEU A 1 220 ? -36.64344 -19.11730 -25.14954 1.000 54.57377  ? 220 LEU A HG   1 
ATOM   3321 H HD11 . LEU A 1 220 ? -38.58117 -18.78690 -26.36157 1.000 58.78016  ? 220 LEU A HD11 1 
ATOM   3322 H HD12 . LEU A 1 220 ? -39.39538 -18.52890 -25.02216 1.000 58.78016  ? 220 LEU A HD12 1 
ATOM   3323 H HD13 . LEU A 1 220 ? -38.28680 -17.49178 -25.49007 1.000 58.78016  ? 220 LEU A HD13 1 
ATOM   3324 H HD21 . LEU A 1 220 ? -37.20792 -17.62973 -23.37549 1.000 58.52734  ? 220 LEU A HD21 1 
ATOM   3325 H HD22 . LEU A 1 220 ? -38.09046 -18.79460 -22.75282 1.000 58.52734  ? 220 LEU A HD22 1 
ATOM   3326 H HD23 . LEU A 1 220 ? -36.51653 -18.97026 -22.87700 1.000 58.52734  ? 220 LEU A HD23 1 
ATOM   3327 N N    . ASN A 1 221 ? -37.34006 -23.52012 -22.71878 1.000 52.84850  ? 221 ASN A N    1 
ATOM   3328 C CA   . ASN A 1 221 ? -37.79361 -24.87618 -22.44822 1.000 55.00414  ? 221 ASN A CA   1 
ATOM   3329 C C    . ASN A 1 221 ? -39.07909 -24.84903 -21.62828 1.000 57.49888  ? 221 ASN A C    1 
ATOM   3330 O O    . ASN A 1 221 ? -39.46484 -23.82525 -21.05731 1.000 56.86515  ? 221 ASN A O    1 
ATOM   3331 C CB   . ASN A 1 221 ? -36.70964 -25.68932 -21.72528 1.000 50.64683  ? 221 ASN A CB   1 
ATOM   3332 C CG   . ASN A 1 221 ? -36.42776 -25.18644 -20.32099 1.000 58.30494  ? 221 ASN A CG   1 
ATOM   3333 O OD1  . ASN A 1 221 ? -37.11051 -24.29809 -19.80836 1.000 56.68975  ? 221 ASN A OD1  1 
ATOM   3334 N ND2  . ASN A 1 221 ? -35.41430 -25.76617 -19.68586 1.000 61.53958  ? 221 ASN A ND2  1 
ATOM   3335 H H    . ASN A 1 221 ? -37.15213 -23.07106 -22.00981 1.000 63.41197  ? 221 ASN A H    1 
ATOM   3336 H HA   . ASN A 1 221 ? -37.98937 -25.31660 -23.29001 1.000 65.99874  ? 221 ASN A HA   1 
ATOM   3337 H HB2  . ASN A 1 221 ? -36.99973 -26.61258 -21.65943 1.000 60.76996  ? 221 ASN A HB2  1 
ATOM   3338 H HB3  . ASN A 1 221 ? -35.88478 -25.63614 -22.23290 1.000 60.76996  ? 221 ASN A HB3  1 
ATOM   3339 H HD21 . ASN A 1 221 ? -35.21008 -25.52031 -18.88745 1.000 73.84127  ? 221 ASN A HD21 1 
ATOM   3340 H HD22 . ASN A 1 221 ? -34.96277 -26.38714 -20.07330 1.000 73.84127  ? 221 ASN A HD22 1 
ATOM   3341 N N    . ARG A 1 222 ? -39.74104 -26.00598 -21.57227 1.000 62.74636  ? 222 ARG A N    1 
ATOM   3342 C CA   . ARG A 1 222 ? -41.04749 -26.11754 -20.93682 1.000 78.97794  ? 222 ARG A CA   1 
ATOM   3343 C C    . ARG A 1 222 ? -40.97585 -26.19968 -19.41800 1.000 71.06633  ? 222 ARG A C    1 
ATOM   3344 O O    . ARG A 1 222 ? -42.02542 -26.19349 -18.76594 1.000 75.56371  ? 222 ARG A O    1 
ATOM   3345 C CB   . ARG A 1 222 ? -41.78161 -27.35197 -21.47219 1.000 76.18850  ? 222 ARG A CB   1 
ATOM   3346 H H    . ARG A 1 222 ? -39.44941 -26.74611 -21.89901 1.000 75.28940  ? 222 ARG A H    1 
ATOM   3347 H HA   . ARG A 1 222 ? -41.56452 -25.32891 -21.16408 1.000 94.76730  ? 222 ARG A HA   1 
ATOM   3348 N N    . PHE A 1 223 ? -39.78174 -26.26460 -18.83929 1.000 63.61714  ? 223 PHE A N    1 
ATOM   3349 C CA   . PHE A 1 223 ? -39.64443 -26.49910 -17.41362 1.000 56.69581  ? 223 PHE A CA   1 
ATOM   3350 C C    . PHE A 1 223 ? -39.74945 -25.19100 -16.63064 1.000 51.87035  ? 223 PHE A C    1 
ATOM   3351 O O    . PHE A 1 223 ? -40.01858 -24.11757 -17.17557 1.000 54.32134  ? 223 PHE A O    1 
ATOM   3352 C CB   . PHE A 1 223 ? -38.31552 -27.19415 -17.12031 1.000 54.83675  ? 223 PHE A CB   1 
ATOM   3353 C CG   . PHE A 1 223 ? -37.99587 -28.31896 -18.06809 1.000 72.23556  ? 223 PHE A CG   1 
ATOM   3354 C CD1  . PHE A 1 223 ? -38.99649 -29.14668 -18.55340 1.000 68.16981  ? 223 PHE A CD1  1 
ATOM   3355 C CD2  . PHE A 1 223 ? -36.69252 -28.54354 -18.47959 1.000 67.95141  ? 223 PHE A CD2  1 
ATOM   3356 C CE1  . PHE A 1 223 ? -38.70030 -30.17583 -19.42726 1.000 68.22835  ? 223 PHE A CE1  1 
ATOM   3357 C CE2  . PHE A 1 223 ? -36.39130 -29.57311 -19.35306 1.000 71.18406  ? 223 PHE A CE2  1 
ATOM   3358 C CZ   . PHE A 1 223 ? -37.39594 -30.39076 -19.82528 1.000 81.90025  ? 223 PHE A CZ   1 
ATOM   3359 H H    . PHE A 1 223 ? -39.03462 -26.17519 -19.25573 1.000 76.33434  ? 223 PHE A H    1 
ATOM   3360 H HA   . PHE A 1 223 ? -40.37219 -27.07588 -17.13329 1.000 68.02874  ? 223 PHE A HA   1 
ATOM   3361 H HB2  . PHE A 1 223 ? -37.60128 -26.54100 -17.18477 1.000 65.79787  ? 223 PHE A HB2  1 
ATOM   3362 H HB3  . PHE A 1 223 ? -38.34790 -27.56295 -16.22374 1.000 65.79787  ? 223 PHE A HB3  1 
ATOM   3363 H HD1  . PHE A 1 223 ? -39.87696 -29.00793 -18.28802 1.000 81.79755  ? 223 PHE A HD1  1 
ATOM   3364 H HD2  . PHE A 1 223 ? -36.01088 -27.99491 -18.16450 1.000 81.53546  ? 223 PHE A HD2  1 
ATOM   3365 H HE1  . PHE A 1 223 ? -39.38011 -30.72385 -19.74731 1.000 81.86779  ? 223 PHE A HE1  1 
ATOM   3366 H HE2  . PHE A 1 223 ? -35.51203 -29.71357 -19.62147 1.000 85.41464  ? 223 PHE A HE2  1 
ATOM   3367 H HZ   . PHE A 1 223 ? -37.19547 -31.08527 -20.41040 1.000 98.27407  ? 223 PHE A HZ   1 
ATOM   3368 N N    . THR A 1 224 ? -39.54565 -25.29698 -15.32244 1.000 51.49268  ? 224 THR A N    1 
ATOM   3369 C CA   . THR A 1 224 ? -39.46688 -24.14848 -14.42983 1.000 57.48753  ? 224 THR A CA   1 
ATOM   3370 C C    . THR A 1 224 ? -38.66090 -24.58789 -13.21283 1.000 55.78293  ? 224 THR A C    1 
ATOM   3371 O O    . THR A 1 224 ? -38.20049 -25.72972 -13.13480 1.000 51.53026  ? 224 THR A O    1 
ATOM   3372 C CB   . THR A 1 224 ? -40.85939 -23.63648 -14.05208 1.000 54.53376  ? 224 THR A CB   1 
ATOM   3373 O OG1  . THR A 1 224 ? -40.77624 -22.25416 -13.68470 1.000 56.63363  ? 224 THR A OG1  1 
ATOM   3374 C CG2  . THR A 1 224 ? -41.43802 -24.42725 -12.88323 1.000 56.21477  ? 224 THR A CG2  1 
ATOM   3375 H H    . THR A 1 224 ? -39.44673 -26.04789 -14.91508 1.000 61.78499  ? 224 THR A H    1 
ATOM   3376 H HA   . THR A 1 224 ? -39.00226 -23.41798 -14.86731 1.000 68.97880  ? 224 THR A HA   1 
ATOM   3377 H HB   . THR A 1 224 ? -41.45266 -23.74261 -14.81213 1.000 65.43429  ? 224 THR A HB   1 
ATOM   3378 H HG1  . THR A 1 224 ? -40.35406 -22.17359 -12.96298 1.000 67.95413  ? 224 THR A HG1  1 
ATOM   3379 H HG21 . THR A 1 224 ? -42.40139 -24.31805 -12.85335 1.000 67.45149  ? 224 THR A HG21 1 
ATOM   3380 H HG22 . THR A 1 224 ? -41.23101 -25.36940 -12.98524 1.000 67.45149  ? 224 THR A HG22 1 
ATOM   3381 H HG23 . THR A 1 224 ? -41.05923 -24.11031 -12.04838 1.000 67.45149  ? 224 THR A HG23 1 
ATOM   3382 N N    . THR A 1 225 ? -38.49075 -23.68087 -12.25761 1.000 44.16935  ? 225 THR A N    1 
ATOM   3383 C CA   . THR A 1 225 ? -37.63275 -23.99060 -11.12217 1.000 49.09719  ? 225 THR A CA   1 
ATOM   3384 C C    . THR A 1 225 ? -37.82708 -22.93570 -10.04584 1.000 50.85585  ? 225 THR A C    1 
ATOM   3385 O O    . THR A 1 225 ? -38.27942 -21.82052 -10.31900 1.000 56.77562  ? 225 THR A O    1 
ATOM   3386 C CB   . THR A 1 225 ? -36.15843 -24.06808 -11.54867 1.000 49.94487  ? 225 THR A CB   1 
ATOM   3387 O OG1  . THR A 1 225 ? -35.32500 -24.23623 -10.39514 1.000 60.69432  ? 225 THR A OG1  1 
ATOM   3388 C CG2  . THR A 1 225 ? -35.74182 -22.80643 -12.29325 1.000 51.89447  ? 225 THR A CG2  1 
ATOM   3389 H H    . THR A 1 225 ? -38.85172 -22.90040 -12.24518 1.000 52.99699  ? 225 THR A H    1 
ATOM   3390 H HA   . THR A 1 225 ? -37.89524 -24.84462 -10.74449 1.000 58.91040  ? 225 THR A HA   1 
ATOM   3391 H HB   . THR A 1 225 ? -36.04033 -24.82495 -12.14375 1.000 59.92762  ? 225 THR A HB   1 
ATOM   3392 H HG1  . THR A 1 225 ? -35.40723 -25.01546 -10.09242 1.000 72.82695  ? 225 THR A HG1  1 
ATOM   3393 H HG21 . THR A 1 225 ? -35.75102 -22.04688 -11.69001 1.000 62.26713  ? 225 THR A HG21 1 
ATOM   3394 H HG22 . THR A 1 225 ? -34.84676 -22.91299 -12.65162 1.000 62.26713  ? 225 THR A HG22 1 
ATOM   3395 H HG23 . THR A 1 225 ? -36.35542 -22.63497 -13.02468 1.000 62.26713  ? 225 THR A HG23 1 
ATOM   3396 N N    . THR A 1 226 ? -37.48887 -23.31025 -8.81462  1.000 44.95634  ? 226 THR A N    1 
ATOM   3397 C CA   . THR A 1 226 ? -37.46824 -22.35475 -7.72092  1.000 52.52872  ? 226 THR A CA   1 
ATOM   3398 C C    . THR A 1 226 ? -36.16293 -21.56116 -7.73762  1.000 52.60115  ? 226 THR A C    1 
ATOM   3399 O O    . THR A 1 226 ? -35.15616 -21.97501 -8.32039  1.000 50.03433  ? 226 THR A O    1 
ATOM   3400 C CB   . THR A 1 226 ? -37.62398 -23.05873 -6.37153  1.000 55.74203  ? 226 THR A CB   1 
ATOM   3401 O OG1  . THR A 1 226 ? -36.42041 -23.76952 -6.05541  1.000 59.24179  ? 226 THR A OG1  1 
ATOM   3402 C CG2  . THR A 1 226 ? -38.79472 -24.03269 -6.40376  1.000 55.95447  ? 226 THR A CG2  1 
ATOM   3403 H H    . THR A 1 226 ? -37.26829 -24.11078 -8.59079  1.000 53.94138  ? 226 THR A H    1 
ATOM   3404 H HA   . THR A 1 226 ? -38.21134 -21.73981 -7.82368  1.000 63.02823  ? 226 THR A HA   1 
ATOM   3405 H HB   . THR A 1 226 ? -37.79778 -22.39789 -5.68306  1.000 66.88420  ? 226 THR A HB   1 
ATOM   3406 H HG1  . THR A 1 226 ? -36.43313 -24.01277 -5.25150  1.000 71.08392  ? 226 THR A HG1  1 
ATOM   3407 H HG21 . THR A 1 226 ? -39.52944 -23.65165 -6.90962  1.000 67.13914  ? 226 THR A HG21 1 
ATOM   3408 H HG22 . THR A 1 226 ? -38.52274 -24.86464 -6.82183  1.000 67.13914  ? 226 THR A HG22 1 
ATOM   3409 H HG23 . THR A 1 226 ? -39.09693 -24.21817 -5.50089  1.000 67.13914  ? 226 THR A HG23 1 
ATOM   3410 N N    . LEU A 1 227 ? -36.19365 -20.40035 -7.08119  1.000 48.95319  ? 227 LEU A N    1 
ATOM   3411 C CA   . LEU A 1 227 ? -35.00006 -19.56578 -7.00233  1.000 44.93031  ? 227 LEU A CA   1 
ATOM   3412 C C    . LEU A 1 227 ? -33.86602 -20.29884 -6.29707  1.000 55.33306  ? 227 LEU A C    1 
ATOM   3413 O O    . LEU A 1 227 ? -32.70221 -20.19643 -6.70295  1.000 50.90860  ? 227 LEU A O    1 
ATOM   3414 C CB   . LEU A 1 227 ? -35.33270 -18.26059 -6.28165  1.000 46.55457  ? 227 LEU A CB   1 
ATOM   3415 C CG   . LEU A 1 227 ? -34.34033 -17.10505 -6.41532  1.000 48.34678  ? 227 LEU A CG   1 
ATOM   3416 C CD1  . LEU A 1 227 ? -34.11185 -16.74203 -7.88044  1.000 55.08930  ? 227 LEU A CD1  1 
ATOM   3417 C CD2  . LEU A 1 227 ? -34.84546 -15.90479 -5.62731  1.000 41.87127  ? 227 LEU A CD2  1 
ATOM   3418 H H    . LEU A 1 227 ? -36.88299 -20.07932 -6.67950  1.000 58.73761  ? 227 LEU A H    1 
ATOM   3419 H HA   . LEU A 1 227 ? -34.70160 -19.34772 -7.89915  1.000 53.91014  ? 227 LEU A HA   1 
ATOM   3420 H HB2  . LEU A 1 227 ? -36.18231 -17.94147 -6.62404  1.000 55.85925  ? 227 LEU A HB2  1 
ATOM   3421 H HB3  . LEU A 1 227 ? -35.40909 -18.45636 -5.33468  1.000 55.85925  ? 227 LEU A HB3  1 
ATOM   3422 H HG   . LEU A 1 227 ? -33.48185 -17.37446 -6.05292  1.000 58.00990  ? 227 LEU A HG   1 
ATOM   3423 H HD11 . LEU A 1 227 ? -33.38225 -17.27812 -8.22855  1.000 66.10093  ? 227 LEU A HD11 1 
ATOM   3424 H HD12 . LEU A 1 227 ? -34.92302 -16.92263 -8.38074  1.000 66.10093  ? 227 LEU A HD12 1 
ATOM   3425 H HD13 . LEU A 1 227 ? -33.88851 -15.80006 -7.94127  1.000 66.10093  ? 227 LEU A HD13 1 
ATOM   3426 H HD21 . LEU A 1 227 ? -34.34694 -15.11756 -5.89685  1.000 50.23930  ? 227 LEU A HD21 1 
ATOM   3427 H HD22 . LEU A 1 227 ? -35.78895 -15.77882 -5.81401  1.000 50.23930  ? 227 LEU A HD22 1 
ATOM   3428 H HD23 . LEU A 1 227 ? -34.71489 -16.07091 -4.68061  1.000 50.23930  ? 227 LEU A HD23 1 
ATOM   3429 N N    . ASN A 1 228 ? -34.18746 -21.05843 -5.24710  1.000 54.71410  ? 228 ASN A N    1 
ATOM   3430 C CA   . ASN A 1 228 ? -33.14834 -21.76524 -4.50686  1.000 54.76279  ? 228 ASN A CA   1 
ATOM   3431 C C    . ASN A 1 228 ? -32.62448 -22.96735 -5.28466  1.000 53.99909  ? 228 ASN A C    1 
ATOM   3432 O O    . ASN A 1 228 ? -31.43829 -23.29943 -5.18341  1.000 58.82932  ? 228 ASN A O    1 
ATOM   3433 C CB   . ASN A 1 228 ? -33.68413 -22.19513 -3.14090  1.000 43.71351  ? 228 ASN A CB   1 
ATOM   3434 C CG   . ASN A 1 228 ? -32.61816 -22.17001 -2.06408  1.000 59.98355  ? 228 ASN A CG   1 
ATOM   3435 O OD1  . ASN A 1 228 ? -32.10120 -23.21242 -1.65932  1.000 57.07052  ? 228 ASN A OD1  1 
ATOM   3436 N ND2  . ASN A 1 228 ? -32.27797 -20.97169 -1.59714  1.000 65.35708  ? 228 ASN A ND2  1 
ATOM   3437 H H    . ASN A 1 228 ? -34.98564 -21.17769 -4.94996  1.000 65.65069  ? 228 ASN A H    1 
ATOM   3438 H HA   . ASN A 1 228 ? -32.40178 -21.16431 -4.35703  1.000 65.70912  ? 228 ASN A HA   1 
ATOM   3439 H HB2  . ASN A 1 228 ? -34.39474 -21.59087 -2.87480  1.000 52.44998  ? 228 ASN A HB2  1 
ATOM   3440 H HB3  . ASN A 1 228 ? -34.02546 -23.10081 -3.20516  1.000 52.44998  ? 228 ASN A HB3  1 
ATOM   3441 H HD21 . ASN A 1 228 ? -31.67769 -20.90322 -0.98512  1.000 78.42226  ? 228 ASN A HD21 1 
ATOM   3442 H HD22 . ASN A 1 228 ? -32.65834 -20.26549 -1.90731  1.000 78.42226  ? 228 ASN A HD22 1 
ATOM   3443 N N    . ASP A 1 229 ? -33.47985 -23.62817 -6.06657  1.000 58.81120  ? 229 ASP A N    1 
ATOM   3444 C CA   . ASP A 1 229 ? -32.99580 -24.70682 -6.92187  1.000 59.54166  ? 229 ASP A CA   1 
ATOM   3445 C C    . ASP A 1 229 ? -32.05194 -24.17394 -7.99352  1.000 61.82546  ? 229 ASP A C    1 
ATOM   3446 O O    . ASP A 1 229 ? -31.00176 -24.77224 -8.25857  1.000 52.50468  ? 229 ASP A O    1 
ATOM   3447 C CB   . ASP A 1 229 ? -34.17138 -25.44011 -7.56748  1.000 64.93381  ? 229 ASP A CB   1 
ATOM   3448 C CG   . ASP A 1 229 ? -34.98303 -26.24345 -6.56683  1.000 70.68670  ? 229 ASP A CG   1 
ATOM   3449 O OD1  . ASP A 1 229 ? -34.45757 -26.54798 -5.47302  1.000 55.96865  ? 229 ASP A OD1  1 
ATOM   3450 O OD2  . ASP A 1 229 ? -36.14699 -26.57714 -6.88052  1.000 72.84297  ? 229 ASP A OD2  1 
ATOM   3451 H H    . ASP A 1 229 ? -34.32442 -23.47446 -6.11834  1.000 70.56721  ? 229 ASP A H    1 
ATOM   3452 H HA   . ASP A 1 229 ? -32.51035 -25.34327 -6.37400  1.000 71.44377  ? 229 ASP A HA   1 
ATOM   3453 H HB2  . ASP A 1 229 ? -34.76167 -24.79001 -7.97957  1.000 77.91435  ? 229 ASP A HB2  1 
ATOM   3454 H HB3  . ASP A 1 229 ? -33.83185 -26.05239 -8.23884  1.000 77.91435  ? 229 ASP A HB3  1 
ATOM   3455 N N    . PHE A 1 230 ? -32.41321 -23.05316 -8.62476  1.000 59.30111  ? 230 PHE A N    1 
ATOM   3456 C CA   . PHE A 1 230 ? -31.54126 -22.45352 -9.62937  1.000 55.33481  ? 230 PHE A CA   1 
ATOM   3457 C C    . PHE A 1 230 ? -30.18694 -22.09588 -9.03094  1.000 52.88217  ? 230 PHE A C    1 
ATOM   3458 O O    . PHE A 1 230 ? -29.13696 -22.47604 -9.56186  1.000 49.36070  ? 230 PHE A O    1 
ATOM   3459 C CB   . PHE A 1 230 ? -32.20139 -21.20957 -10.22843 1.000 52.63533  ? 230 PHE A CB   1 
ATOM   3460 C CG   . PHE A 1 230 ? -31.32731 -20.47858 -11.21017 1.000 54.07984  ? 230 PHE A CG   1 
ATOM   3461 C CD1  . PHE A 1 230 ? -31.23421 -20.90583 -12.52549 1.000 43.45971  ? 230 PHE A CD1  1 
ATOM   3462 C CD2  . PHE A 1 230 ? -30.58866 -19.37388 -10.81480 1.000 48.38857  ? 230 PHE A CD2  1 
ATOM   3463 C CE1  . PHE A 1 230 ? -30.42747 -20.24233 -13.42939 1.000 45.51138  ? 230 PHE A CE1  1 
ATOM   3464 C CE2  . PHE A 1 230 ? -29.77887 -18.70781 -11.71311 1.000 55.96387  ? 230 PHE A CE2  1 
ATOM   3465 C CZ   . PHE A 1 230 ? -29.69696 -19.14365 -13.02235 1.000 48.17075  ? 230 PHE A CZ   1 
ATOM   3466 H H    . PHE A 1 230 ? -33.14841 -22.62785 -8.48986  1.000 71.15510  ? 230 PHE A H    1 
ATOM   3467 H HA   . PHE A 1 230 ? -31.40320 -23.09607 -10.34279 1.000 66.39555  ? 230 PHE A HA   1 
ATOM   3468 H HB2  . PHE A 1 230 ? -33.00969 -21.47760 -10.69289 1.000 63.15617  ? 230 PHE A HB2  1 
ATOM   3469 H HB3  . PHE A 1 230 ? -32.41964 -20.59501 -9.51039  1.000 63.15617  ? 230 PHE A HB3  1 
ATOM   3470 H HD1  . PHE A 1 230 ? -31.72081 -21.64826 -12.80282 1.000 52.14542  ? 230 PHE A HD1  1 
ATOM   3471 H HD2  . PHE A 1 230 ? -30.63921 -19.07816 -9.93452  1.000 58.06005  ? 230 PHE A HD2  1 
ATOM   3472 H HE1  . PHE A 1 230 ? -30.37645 -20.53514 -14.31061 1.000 54.60743  ? 230 PHE A HE1  1 
ATOM   3473 H HE2  . PHE A 1 230 ? -29.28908 -17.96678 -11.43765 1.000 67.15041  ? 230 PHE A HE2  1 
ATOM   3474 H HZ   . PHE A 1 230 ? -29.15050 -18.69741 -13.62827 1.000 57.79868  ? 230 PHE A HZ   1 
ATOM   3475 N N    . ASN A 1 231 ? -30.19484 -21.36299 -7.91610  1.000 53.44298  ? 231 ASN A N    1 
ATOM   3476 C CA   . ASN A 1 231 ? -28.94504 -20.90502 -7.32044  1.000 53.84926  ? 231 ASN A CA   1 
ATOM   3477 C C    . ASN A 1 231 ? -28.06844 -22.07561 -6.90101  1.000 50.24755  ? 231 ASN A C    1 
ATOM   3478 O O    . ASN A 1 231 ? -26.83871 -22.00472 -7.00836  1.000 57.41859  ? 231 ASN A O    1 
ATOM   3479 C CB   . ASN A 1 231 ? -29.24603 -19.99047 -6.13560  1.000 52.36100  ? 231 ASN A CB   1 
ATOM   3480 C CG   . ASN A 1 231 ? -29.72733 -18.62376 -6.57562  1.000 55.01459  ? 231 ASN A CG   1 
ATOM   3481 O OD1  . ASN A 1 231 ? -29.19151 -18.04737 -7.52131  1.000 60.37128  ? 231 ASN A OD1  1 
ATOM   3482 N ND2  . ASN A 1 231 ? -30.74804 -18.10243 -5.90289  1.000 58.08236  ? 231 ASN A ND2  1 
ATOM   3483 H H    . ASN A 1 231 ? -30.90245 -21.12110 -7.49140  1.000 64.12535  ? 231 ASN A H    1 
ATOM   3484 H HA   . ASN A 1 231 ? -28.44851 -20.39173 -7.97686  1.000 64.61289  ? 231 ASN A HA   1 
ATOM   3485 H HB2  . ASN A 1 231 ? -29.93928 -20.39397 -5.59018  1.000 62.82697  ? 231 ASN A HB2  1 
ATOM   3486 H HB3  . ASN A 1 231 ? -28.43835 -19.87228 -5.61158  1.000 62.82697  ? 231 ASN A HB3  1 
ATOM   3487 H HD21 . ASN A 1 231 ? -31.05443 -17.32825 -6.11825  1.000 69.69260  ? 231 ASN A HD21 1 
ATOM   3488 H HD22 . ASN A 1 231 ? -31.10215 -18.53924 -5.25220  1.000 69.69260  ? 231 ASN A HD22 1 
ATOM   3489 N N    . LEU A 1 232 ? -28.67801 -23.16467 -6.42709  1.000 60.49730  ? 232 LEU A N    1 
ATOM   3490 C CA   . LEU A 1 232 ? -27.90540 -24.36797 -6.13579  1.000 61.81460  ? 232 LEU A CA   1 
ATOM   3491 C C    . LEU A 1 232 ? -27.06110 -24.77024 -7.33884  1.000 56.21388  ? 232 LEU A C    1 
ATOM   3492 O O    . LEU A 1 232 ? -25.86626 -25.05997 -7.21096  1.000 57.19553  ? 232 LEU A O    1 
ATOM   3493 C CB   . LEU A 1 232 ? -28.83332 -25.51657 -5.73762  1.000 60.60634  ? 232 LEU A CB   1 
ATOM   3494 C CG   . LEU A 1 232 ? -29.22472 -25.68197 -4.26663  1.000 65.38599  ? 232 LEU A CG   1 
ATOM   3495 C CD1  . LEU A 1 232 ? -29.81870 -27.07321 -4.04838  1.000 68.54261  ? 232 LEU A CD1  1 
ATOM   3496 C CD2  . LEU A 1 232 ? -28.04806 -25.45690 -3.33153  1.000 58.94654  ? 232 LEU A CD2  1 
ATOM   3497 H H    . LEU A 1 232 ? -29.52091 -23.22960 -6.26925  1.000 72.59053  ? 232 LEU A H    1 
ATOM   3498 H HA   . LEU A 1 232 ? -27.31809 -24.18420 -5.38599  1.000 74.17129  ? 232 LEU A HA   1 
ATOM   3499 H HB2  . LEU A 1 232 ? -29.66138 -25.40467 -6.23025  1.000 72.72139  ? 232 LEU A HB2  1 
ATOM   3500 H HB3  . LEU A 1 232 ? -28.40021 -26.34381 -6.00028  1.000 72.72139  ? 232 LEU A HB3  1 
ATOM   3501 H HG   . LEU A 1 232 ? -29.88817 -25.00905 -4.04777  1.000 78.45696  ? 232 LEU A HG   1 
ATOM   3502 H HD11 . LEU A 1 232 ? -30.19792 -27.38923 -4.88338  1.000 82.24490  ? 232 LEU A HD11 1 
ATOM   3503 H HD12 . LEU A 1 232 ? -29.11587 -27.67432 -3.75582  1.000 82.24490  ? 232 LEU A HD12 1 
ATOM   3504 H HD13 . LEU A 1 232 ? -30.51050 -27.01847 -3.37066  1.000 82.24490  ? 232 LEU A HD13 1 
ATOM   3505 H HD21 . LEU A 1 232 ? -28.23219 -25.88870 -2.48267  1.000 70.72963  ? 232 LEU A HD21 1 
ATOM   3506 H HD22 . LEU A 1 232 ? -27.25027 -25.83813 -3.73039  1.000 70.72963  ? 232 LEU A HD22 1 
ATOM   3507 H HD23 . LEU A 1 232 ? -27.92821 -24.50356 -3.19856  1.000 70.72963  ? 232 LEU A HD23 1 
ATOM   3508 N N    . VAL A 1 233 ? -27.67649 -24.79052 -8.52275  1.000 57.88912  ? 233 VAL A N    1 
ATOM   3509 C CA   . VAL A 1 233 ? -26.95536 -25.15667 -9.73601  1.000 58.05647  ? 233 VAL A CA   1 
ATOM   3510 C C    . VAL A 1 233 ? -25.97813 -24.05697 -10.13604 1.000 60.44675  ? 233 VAL A C    1 
ATOM   3511 O O    . VAL A 1 233 ? -24.82170 -24.33076 -10.48092 1.000 59.34595  ? 233 VAL A O    1 
ATOM   3512 C CB   . VAL A 1 233 ? -27.95272 -25.45672 -10.87028 1.000 51.76106  ? 233 VAL A CB   1 
ATOM   3513 C CG1  . VAL A 1 233 ? -27.20506 -25.84158 -12.14137 1.000 60.07538  ? 233 VAL A CG1  1 
ATOM   3514 C CG2  . VAL A 1 233 ? -28.93268 -26.54869 -10.44880 1.000 63.18837  ? 233 VAL A CG2  1 
ATOM   3515 H H    . VAL A 1 233 ? -28.50519 -24.59754 -8.64768  1.000 69.46072  ? 233 VAL A H    1 
ATOM   3516 H HA   . VAL A 1 233 ? -26.44215 -25.95991 -9.55621  1.000 69.66154  ? 233 VAL A HA   1 
ATOM   3517 H HB   . VAL A 1 233 ? -28.47050 -24.65877 -11.06024 1.000 62.10705  ? 233 VAL A HB   1 
ATOM   3518 H HG11 . VAL A 1 233 ? -26.31367 -26.14209 -11.90471 1.000 72.08423  ? 233 VAL A HG11 1 
ATOM   3519 H HG12 . VAL A 1 233 ? -27.68719 -26.55532 -12.58750 1.000 72.08423  ? 233 VAL A HG12 1 
ATOM   3520 H HG13 . VAL A 1 233 ? -27.14957 -25.06657 -12.72204 1.000 72.08423  ? 233 VAL A HG13 1 
ATOM   3521 H HG21 . VAL A 1 233 ? -29.46950 -26.80425 -11.21523 1.000 75.81981  ? 233 VAL A HG21 1 
ATOM   3522 H HG22 . VAL A 1 233 ? -28.43247 -27.31420 -10.12527 1.000 75.81981  ? 233 VAL A HG22 1 
ATOM   3523 H HG23 . VAL A 1 233 ? -29.50426 -26.20531 -9.74432  1.000 75.81981  ? 233 VAL A HG23 1 
ATOM   3524 N N    . ALA A 1 234 ? -26.42286 -22.79726 -10.09234 1.000 55.67574  ? 234 ALA A N    1 
ATOM   3525 C CA   . ALA A 1 234 ? -25.60526 -21.70164 -10.60422 1.000 54.56366  ? 234 ALA A CA   1 
ATOM   3526 C C    . ALA A 1 234 ? -24.27254 -21.61141 -9.87534  1.000 54.13055  ? 234 ALA A C    1 
ATOM   3527 O O    . ALA A 1 234 ? -23.22484 -21.42105 -10.50319 1.000 53.07683  ? 234 ALA A O    1 
ATOM   3528 C CB   . ALA A 1 234 ? -26.36431 -20.38066 -10.48790 1.000 52.85065  ? 234 ALA A CB   1 
ATOM   3529 H H    . ALA A 1 234 ? -27.18477 -22.55555 -9.77505  1.000 66.80466  ? 234 ALA A H    1 
ATOM   3530 H HA   . ALA A 1 234 ? -25.42332 -21.86655 -11.54262 1.000 65.47017  ? 234 ALA A HA   1 
ATOM   3531 H HB1  . ALA A 1 234 ? -26.81863 -20.35186 -9.63136  1.000 63.41455  ? 234 ALA A HB1  1 
ATOM   3532 H HB2  . ALA A 1 234 ? -25.73307 -19.64699 -10.55235 1.000 63.41455  ? 234 ALA A HB2  1 
ATOM   3533 H HB3  . ALA A 1 234 ? -27.01188 -20.32408 -11.20787 1.000 63.41455  ? 234 ALA A HB3  1 
ATOM   3534 N N    . MET A 1 235 ? -24.28959 -21.73813 -8.54968  1.000 47.33814  ? 235 MET A N    1 
ATOM   3535 C CA   . MET A 1 235 ? -23.03518 -21.70785 -7.80946  1.000 55.62953  ? 235 MET A CA   1 
ATOM   3536 C C    . MET A 1 235 ? -22.15580 -22.90630 -8.14223  1.000 52.84483  ? 235 MET A C    1 
ATOM   3537 O O    . MET A 1 235 ? -20.92897 -22.80937 -8.03991  1.000 48.02315  ? 235 MET A O    1 
ATOM   3538 C CB   . MET A 1 235 ? -23.32175 -21.62106 -6.31124  1.000 61.28884  ? 235 MET A CB   1 
ATOM   3539 C CG   . MET A 1 235 ? -23.37856 -20.17881 -5.80511  1.000 76.76722  ? 235 MET A CG   1 
ATOM   3540 S SD   . MET A 1 235 ? -24.27779 -19.95641 -4.25916  1.000 86.48794  ? 235 MET A SD   1 
ATOM   3541 C CE   . MET A 1 235 ? -25.95875 -19.93530 -4.86805  1.000 64.84317  ? 235 MET A CE   1 
ATOM   3542 H H    . MET A 1 235 ? -24.99549 -21.84001 -8.06913  1.000 56.79953  ? 235 MET A H    1 
ATOM   3543 H HA   . MET A 1 235 ? -22.54367 -20.90761 -8.05225  1.000 66.74920  ? 235 MET A HA   1 
ATOM   3544 H HB2  . MET A 1 235 ? -24.17833 -22.03796 -6.12859  1.000 73.54038  ? 235 MET A HB2  1 
ATOM   3545 H HB3  . MET A 1 235 ? -22.61855 -22.08212 -5.82768  1.000 73.54038  ? 235 MET A HB3  1 
ATOM   3546 H HG2  . MET A 1 235 ? -22.47150 -19.86622 -5.66221  1.000 92.11443  ? 235 MET A HG2  1 
ATOM   3547 H HG3  . MET A 1 235 ? -23.81549 -19.63304 -6.47751  1.000 92.11443  ? 235 MET A HG3  1 
ATOM   3548 H HE1  . MET A 1 235 ? -25.97066 -19.52818 -5.74840  1.000 77.80557  ? 235 MET A HE1  1 
ATOM   3549 H HE2  . MET A 1 235 ? -26.28709 -20.84653 -4.92055  1.000 77.80557  ? 235 MET A HE2  1 
ATOM   3550 H HE3  . MET A 1 235 ? -26.50922 -19.42000 -4.25784  1.000 77.80557  ? 235 MET A HE3  1 
ATOM   3551 N N    . LYS A 1 236 ? -22.74814 -24.02877 -8.56377  1.000 58.16679  ? 236 LYS A N    1 
ATOM   3552 C CA   . LYS A 1 236 ? -21.94024 -25.14258 -9.05023  1.000 61.05481  ? 236 LYS A CA   1 
ATOM   3553 C C    . LYS A 1 236 ? -21.13438 -24.74513 -10.28060 1.000 54.04654  ? 236 LYS A C    1 
ATOM   3554 O O    . LYS A 1 236 ? -20.01201 -25.22742 -10.47219 1.000 51.70757  ? 236 LYS A O    1 
ATOM   3555 C CB   . LYS A 1 236 ? -22.83452 -26.34278 -9.36822  1.000 55.73951  ? 236 LYS A CB   1 
ATOM   3556 H H    . LYS A 1 236 ? -23.59716 -24.16508 -8.57699  1.000 69.79392  ? 236 LYS A H    1 
ATOM   3557 H HA   . LYS A 1 236 ? -21.32030 -25.40855 -8.35321  1.000 73.25955  ? 236 LYS A HA   1 
ATOM   3558 N N    . TYR A 1 237 ? -21.68095 -23.86193 -11.11465 1.000 52.97728  ? 237 TYR A N    1 
ATOM   3559 C CA   . TYR A 1 237 ? -21.03645 -23.43476 -12.34831 1.000 48.40256  ? 237 TYR A CA   1 
ATOM   3560 C C    . TYR A 1 237 ? -20.32986 -22.09037 -12.21995 1.000 46.16231  ? 237 TYR A C    1 
ATOM   3561 O O    . TYR A 1 237 ? -19.92990 -21.51289 -13.23448 1.000 45.35687  ? 237 TYR A O    1 
ATOM   3562 C CB   . TYR A 1 237 ? -22.06880 -23.38085 -13.47503 1.000 47.37945  ? 237 TYR A CB   1 
ATOM   3563 C CG   . TYR A 1 237 ? -22.51325 -24.75434 -13.92134 1.000 55.44377  ? 237 TYR A CG   1 
ATOM   3564 C CD1  . TYR A 1 237 ? -23.55006 -25.41760 -13.27581 1.000 59.12944  ? 237 TYR A CD1  1 
ATOM   3565 C CD2  . TYR A 1 237 ? -21.88366 -25.39595 -14.97807 1.000 53.08301  ? 237 TYR A CD2  1 
ATOM   3566 C CE1  . TYR A 1 237 ? -23.95236 -26.67788 -13.67971 1.000 61.63365  ? 237 TYR A CE1  1 
ATOM   3567 C CE2  . TYR A 1 237 ? -22.27530 -26.65351 -15.38379 1.000 60.17098  ? 237 TYR A CE2  1 
ATOM   3568 C CZ   . TYR A 1 237 ? -23.31204 -27.28796 -14.73574 1.000 56.10132  ? 237 TYR A CZ   1 
ATOM   3569 O OH   . TYR A 1 237 ? -23.70236 -28.53983 -15.14360 1.000 62.26612  ? 237 TYR A OH   1 
ATOM   3570 H H    . TYR A 1 237 ? -22.44406 -23.48838 -10.98150 1.000 63.56650  ? 237 TYR A H    1 
ATOM   3571 H HA   . TYR A 1 237 ? -20.36122 -24.08975 -12.58486 1.000 58.07684  ? 237 TYR A HA   1 
ATOM   3572 H HB2  . TYR A 1 237 ? -22.85054 -22.89748 -13.16496 1.000 56.84911  ? 237 TYR A HB2  1 
ATOM   3573 H HB3  . TYR A 1 237 ? -21.67976 -22.92729 -14.23911 1.000 56.84911  ? 237 TYR A HB3  1 
ATOM   3574 H HD1  . TYR A 1 237 ? -23.98037 -25.00739 -12.56064 1.000 70.94910  ? 237 TYR A HD1  1 
ATOM   3575 H HD2  . TYR A 1 237 ? -21.18517 -24.97005 -15.42036 1.000 63.69338  ? 237 TYR A HD2  1 
ATOM   3576 H HE1  . TYR A 1 237 ? -24.64974 -27.10996 -13.24169 1.000 73.95416  ? 237 TYR A HE1  1 
ATOM   3577 H HE2  . TYR A 1 237 ? -21.84148 -27.07192 -16.09205 1.000 72.19895  ? 237 TYR A HE2  1 
ATOM   3578 H HH   . TYR A 1 237 ? -23.24534 -28.78183 -15.80554 1.000 74.71312  ? 237 TYR A HH   1 
ATOM   3579 N N    . ASN A 1 238 ? -20.15858 -21.58288 -11.00266 1.000 46.88979  ? 238 ASN A N    1 
ATOM   3580 C CA   . ASN A 1 238 ? -19.44487 -20.32879 -10.77626 1.000 56.03198  ? 238 ASN A CA   1 
ATOM   3581 C C    . ASN A 1 238 ? -20.23834 -19.13331 -11.30011 1.000 53.97487  ? 238 ASN A C    1 
ATOM   3582 O O    . ASN A 1 238 ? -19.67217 -18.17729 -11.83391 1.000 45.90845  ? 238 ASN A O    1 
ATOM   3583 C CB   . ASN A 1 238 ? -18.05195 -20.36525 -11.40131 1.000 50.89015  ? 238 ASN A CB   1 
ATOM   3584 C CG   . ASN A 1 238 ? -17.03187 -19.65982 -10.55236 1.000 59.69262  ? 238 ASN A CG   1 
ATOM   3585 O OD1  . ASN A 1 238 ? -16.82568 -18.45471 -10.68381 1.000 67.90843  ? 238 ASN A OD1  1 
ATOM   3586 N ND2  . ASN A 1 238 ? -16.40007 -20.40261 -9.65096  1.000 70.03184  ? 238 ASN A ND2  1 
ATOM   3587 H H    . ASN A 1 238 ? -20.45021 -21.95092 -10.28217 1.000 56.26152  ? 238 ASN A H    1 
ATOM   3588 H HA   . ASN A 1 238 ? -19.34074 -20.20693 -9.81959  1.000 67.23215  ? 238 ASN A HA   1 
ATOM   3589 H HB2  . ASN A 1 238 ? -17.77327 -21.28859 -11.50465 1.000 61.06195  ? 238 ASN A HB2  1 
ATOM   3590 H HB3  . ASN A 1 238 ? -18.07969 -19.92823 -12.26684 1.000 61.06195  ? 238 ASN A HB3  1 
ATOM   3591 H HD21 . ASN A 1 238 ? -15.80689 -20.04673 -9.13999  1.000 84.03198  ? 238 ASN A HD21 1 
ATOM   3592 H HD22 . ASN A 1 238 ? -16.58409 -21.23953 -9.57816  1.000 84.03198  ? 238 ASN A HD22 1 
ATOM   3593 N N    . TYR A 1 239 ? -21.55788 -19.19977 -11.15379 1.000 56.55426  ? 239 TYR A N    1 
ATOM   3594 C CA   . TYR A 1 239 ? -22.45188 -18.08463 -11.42370 1.000 42.26669  ? 239 TYR A CA   1 
ATOM   3595 C C    . TYR A 1 239 ? -22.84587 -17.43192 -10.10599 1.000 42.94994  ? 239 TYR A C    1 
ATOM   3596 O O    . TYR A 1 239 ? -23.12808 -18.12271 -9.12206  1.000 45.22039  ? 239 TYR A O    1 
ATOM   3597 C CB   . TYR A 1 239 ? -23.70871 -18.55325 -12.15991 1.000 39.10127  ? 239 TYR A CB   1 
ATOM   3598 C CG   . TYR A 1 239 ? -23.59698 -18.56694 -13.66676 1.000 37.96244  ? 239 TYR A CG   1 
ATOM   3599 C CD1  . TYR A 1 239 ? -22.59678 -19.28615 -14.30606 1.000 47.64043  ? 239 TYR A CD1  1 
ATOM   3600 C CD2  . TYR A 1 239 ? -24.51056 -17.87544 -14.45190 1.000 42.74995  ? 239 TYR A CD2  1 
ATOM   3601 C CE1  . TYR A 1 239 ? -22.50000 -19.30076 -15.68876 1.000 41.04360  ? 239 TYR A CE1  1 
ATOM   3602 C CE2  . TYR A 1 239 ? -24.42458 -17.88639 -15.82888 1.000 43.22234  ? 239 TYR A CE2  1 
ATOM   3603 C CZ   . TYR A 1 239 ? -23.41926 -18.59778 -16.44231 1.000 41.47547  ? 239 TYR A CZ   1 
ATOM   3604 O OH   . TYR A 1 239 ? -23.34100 -18.60195 -17.81444 1.000 43.27092  ? 239 TYR A OH   1 
ATOM   3605 H H    . TYR A 1 239 ? -21.97129 -19.90620 -10.88986 1.000 67.85889  ? 239 TYR A H    1 
ATOM   3606 H HA   . TYR A 1 239 ? -22.00263 -17.43141 -11.98261 1.000 50.71380  ? 239 TYR A HA   1 
ATOM   3607 H HB2  . TYR A 1 239 ? -23.91233 -19.45783 -11.87500 1.000 46.91530  ? 239 TYR A HB2  1 
ATOM   3608 H HB3  . TYR A 1 239 ? -24.44000 -17.95976 -11.92775 1.000 46.91530  ? 239 TYR A HB3  1 
ATOM   3609 H HD1  . TYR A 1 239 ? -21.98208 -19.76563 -13.79897 1.000 57.16229  ? 239 TYR A HD1  1 
ATOM   3610 H HD2  . TYR A 1 239 ? -25.19346 -17.39576 -14.04148 1.000 51.29372  ? 239 TYR A HD2  1 
ATOM   3611 H HE1  . TYR A 1 239 ? -21.82109 -19.78037 -16.10584 1.000 49.24609  ? 239 TYR A HE1  1 
ATOM   3612 H HE2  . TYR A 1 239 ? -25.04282 -17.41545 -16.33966 1.000 51.86058  ? 239 TYR A HE2  1 
ATOM   3613 H HH   . TYR A 1 239 ? -23.98201 -18.16761 -18.14009 1.000 51.91887  ? 239 TYR A HH   1 
ATOM   3614 N N    . GLU A 1 240 ? -22.85492 -16.10133 -10.08836 1.000 46.51451  ? 240 GLU A N    1 
ATOM   3615 C CA   . GLU A 1 240 ? -23.32696 -15.38396 -8.91501  1.000 54.84857  ? 240 GLU A CA   1 
ATOM   3616 C C    . GLU A 1 240 ? -24.77297 -15.77854 -8.61740  1.000 50.18319  ? 240 GLU A C    1 
ATOM   3617 O O    . GLU A 1 240 ? -25.56071 -16.01889 -9.53737  1.000 48.22446  ? 240 GLU A O    1 
ATOM   3618 C CB   . GLU A 1 240 ? -23.23507 -13.87522 -9.13267  1.000 54.71173  ? 240 GLU A CB   1 
ATOM   3619 C CG   . GLU A 1 240 ? -21.82157 -13.32598 -9.10836  1.000 55.81690  ? 240 GLU A CG   1 
ATOM   3620 C CD   . GLU A 1 240 ? -21.24788 -13.26791 -7.70701  1.000 60.75927  ? 240 GLU A CD   1 
ATOM   3621 O OE1  . GLU A 1 240 ? -21.97181 -13.62165 -6.75359  1.000 71.35763  ? 240 GLU A OE1  1 
ATOM   3622 O OE2  . GLU A 1 240 ? -20.07562 -12.86641 -7.55645  1.000 63.77737  ? 240 GLU A OE2  1 
ATOM   3623 H H    . GLU A 1 240 ? -22.59565 -15.59859 -10.73614 1.000 55.81119  ? 240 GLU A H    1 
ATOM   3624 H HA   . GLU A 1 240 ? -22.77579 -15.61166 -8.14999  1.000 65.81205  ? 240 GLU A HA   1 
ATOM   3625 H HB2  . GLU A 1 240 ? -23.61774 -13.66337 -9.99846  1.000 65.64784  ? 240 GLU A HB2  1 
ATOM   3626 H HB3  . GLU A 1 240 ? -23.73536 -13.43007 -8.43093  1.000 65.64784  ? 240 GLU A HB3  1 
ATOM   3627 H HG2  . GLU A 1 240 ? -21.24982 -13.89734 -9.64459  1.000 66.97406  ? 240 GLU A HG2  1 
ATOM   3628 H HG3  . GLU A 1 240 ? -21.82452 -12.42603 -9.47028  1.000 66.97406  ? 240 GLU A HG3  1 
ATOM   3629 N N    . PRO A 1 241 ? -25.15572 -15.84723 -7.34485  1.000 47.91931  ? 241 PRO A N    1 
ATOM   3630 C CA   . PRO A 1 241 ? -26.53356 -16.22300 -7.02304  1.000 55.26269  ? 241 PRO A CA   1 
ATOM   3631 C C    . PRO A 1 241 ? -27.50763 -15.13086 -7.42419  1.000 52.35522  ? 241 PRO A C    1 
ATOM   3632 O O    . PRO A 1 241 ? -27.19329 -13.93851 -7.39335  1.000 52.35472  ? 241 PRO A O    1 
ATOM   3633 C CB   . PRO A 1 241 ? -26.50428 -16.41403 -5.50326  1.000 51.97970  ? 241 PRO A CB   1 
ATOM   3634 C CG   . PRO A 1 241 ? -25.44607 -15.48686 -5.04648  1.000 48.71906  ? 241 PRO A CG   1 
ATOM   3635 C CD   . PRO A 1 241 ? -24.39233 -15.49569 -6.13341  1.000 52.85341  ? 241 PRO A CD   1 
ATOM   3636 H HA   . PRO A 1 241 ? -26.77921 -17.05805 -7.45111  1.000 66.30900  ? 241 PRO A HA   1 
ATOM   3637 H HB2  . PRO A 1 241 ? -27.36442 -16.18056 -5.12045  1.000 62.36941  ? 241 PRO A HB2  1 
ATOM   3638 H HB3  . PRO A 1 241 ? -26.28301 -17.33317 -5.28617  1.000 62.36941  ? 241 PRO A HB3  1 
ATOM   3639 H HG2  . PRO A 1 241 ? -25.81640 -14.59740 -4.93407  1.000 58.45664  ? 241 PRO A HG2  1 
ATOM   3640 H HG3  . PRO A 1 241 ? -25.07607 -15.80076 -4.20656  1.000 58.45664  ? 241 PRO A HG3  1 
ATOM   3641 H HD2  . PRO A 1 241 ? -23.98369 -14.62074 -6.22490  1.000 63.41786  ? 241 PRO A HD2  1 
ATOM   3642 H HD3  . PRO A 1 241 ? -23.71193 -16.16197 -5.94891  1.000 63.41786  ? 241 PRO A HD3  1 
ATOM   3643 N N    . LEU A 1 242 ? -28.70235 -15.55635 -7.81607  1.000 49.32661  ? 242 LEU A N    1 
ATOM   3644 C CA   . LEU A 1 242 ? -29.78046 -14.63509 -8.13870  1.000 48.48724  ? 242 LEU A CA   1 
ATOM   3645 C C    . LEU A 1 242 ? -30.56396 -14.33555 -6.86651  1.000 49.49548  ? 242 LEU A C    1 
ATOM   3646 O O    . LEU A 1 242 ? -30.94669 -15.25425 -6.13314  1.000 42.98583  ? 242 LEU A O    1 
ATOM   3647 C CB   . LEU A 1 242 ? -30.68916 -15.22902 -9.21330  1.000 39.41898  ? 242 LEU A CB   1 
ATOM   3648 C CG   . LEU A 1 242 ? -31.60836 -14.25893 -9.95497  1.000 43.33401  ? 242 LEU A CG   1 
ATOM   3649 C CD1  . LEU A 1 242 ? -30.80361 -13.26125 -10.78727 1.000 39.06550  ? 242 LEU A CD1  1 
ATOM   3650 C CD2  . LEU A 1 242 ? -32.57990 -15.04090 -10.82758 1.000 36.51107  ? 242 LEU A CD2  1 
ATOM   3651 H H    . LEU A 1 242 ? -28.91468 -16.38512 -7.90359  1.000 59.18570  ? 242 LEU A H    1 
ATOM   3652 H HA   . LEU A 1 242 ? -29.42305 -13.80302 -8.48629  1.000 58.17846  ? 242 LEU A HA   1 
ATOM   3653 H HB2  . LEU A 1 242 ? -30.12617 -15.65200 -9.88041  1.000 47.29654  ? 242 LEU A HB2  1 
ATOM   3654 H HB3  . LEU A 1 242 ? -31.25802 -15.89151 -8.79092  1.000 47.29654  ? 242 LEU A HB3  1 
ATOM   3655 H HG   . LEU A 1 242 ? -32.11760 -13.74323 -9.31029  1.000 51.99458  ? 242 LEU A HG   1 
ATOM   3656 H HD11 . LEU A 1 242 ? -30.27754 -12.70497 -10.19170 1.000 46.87237  ? 242 LEU A HD11 1 
ATOM   3657 H HD12 . LEU A 1 242 ? -30.21814 -13.74986 -11.38677 1.000 46.87237  ? 242 LEU A HD12 1 
ATOM   3658 H HD13 . LEU A 1 242 ? -31.41626 -12.71045 -11.29930 1.000 46.87237  ? 242 LEU A HD13 1 
ATOM   3659 H HD21 . LEU A 1 242 ? -32.12857 -15.82435 -11.17888 1.000 43.80706  ? 242 LEU A HD21 1 
ATOM   3660 H HD22 . LEU A 1 242 ? -33.34060 -15.31081 -10.28962 1.000 43.80706  ? 242 LEU A HD22 1 
ATOM   3661 H HD23 . LEU A 1 242 ? -32.87526 -14.47427 -11.55737 1.000 43.80706  ? 242 LEU A HD23 1 
ATOM   3662 N N    . THR A 1 243 ? -30.77428 -13.05222 -6.59491  1.000 47.64367  ? 243 THR A N    1 
ATOM   3663 C CA   . THR A 1 243 ? -31.50927 -12.60403 -5.42320  1.000 43.36282  ? 243 THR A CA   1 
ATOM   3664 C C    . THR A 1 243 ? -32.88286 -12.09455 -5.84175  1.000 40.73745  ? 243 THR A C    1 
ATOM   3665 O O    . THR A 1 243 ? -33.13951 -11.82632 -7.01858  1.000 42.26527  ? 243 THR A O    1 
ATOM   3666 C CB   . THR A 1 243 ? -30.74570 -11.50001 -4.67998  1.000 44.05209  ? 243 THR A CB   1 
ATOM   3667 O OG1  . THR A 1 243 ? -30.91503 -10.24971 -5.36084  1.000 46.17046  ? 243 THR A OG1  1 
ATOM   3668 C CG2  . THR A 1 243 ? -29.25659 -11.83311 -4.60458  1.000 44.12590  ? 243 THR A CG2  1 
ATOM   3669 H H    . THR A 1 243 ? -30.49251 -12.40729 -7.08915  1.000 57.16618  ? 243 THR A H    1 
ATOM   3670 H HA   . THR A 1 243 ? -31.62811 -13.34736 -4.81145  1.000 52.02916  ? 243 THR A HA   1 
ATOM   3671 H HB   . THR A 1 243 ? -31.09079 -11.42536 -3.77652  1.000 52.85628  ? 243 THR A HB   1 
ATOM   3672 H HG1  . THR A 1 243 ? -30.55486 -10.28430 -6.11892  1.000 55.39832  ? 243 THR A HG1  1 
ATOM   3673 H HG21 . THR A 1 243 ? -28.81906 -11.25327 -3.96173  1.000 52.94485  ? 243 THR A HG21 1 
ATOM   3674 H HG22 . THR A 1 243 ? -29.13648 -12.75547 -4.32937  1.000 52.94485  ? 243 THR A HG22 1 
ATOM   3675 H HG23 . THR A 1 243 ? -28.84415 -11.70761 -5.47351  1.000 52.94485  ? 243 THR A HG23 1 
ATOM   3676 N N    . GLN A 1 244 ? -33.77510 -11.96783 -4.85719  1.000 43.68463  ? 244 GLN A N    1 
ATOM   3677 C CA   . GLN A 1 244 ? -35.09631 -11.41654 -5.13871  1.000 43.51660  ? 244 GLN A CA   1 
ATOM   3678 C C    . GLN A 1 244 ? -34.99939 -10.01731 -5.73024  1.000 41.95245  ? 244 GLN A C    1 
ATOM   3679 O O    . GLN A 1 244 ? -35.84647 -9.62351  -6.54103  1.000 37.55320  ? 244 GLN A O    1 
ATOM   3680 C CB   . GLN A 1 244 ? -35.94215 -11.38458 -3.86664  1.000 40.78485  ? 244 GLN A CB   1 
ATOM   3681 C CG   . GLN A 1 244 ? -37.37255 -10.91894 -4.10218  1.000 39.45068  ? 244 GLN A CG   1 
ATOM   3682 C CD   . GLN A 1 244 ? -38.12190 -11.82482 -5.05752  1.000 45.83311  ? 244 GLN A CD   1 
ATOM   3683 O OE1  . GLN A 1 244 ? -38.14846 -13.04371 -4.88137  1.000 56.24668  ? 244 GLN A OE1  1 
ATOM   3684 N NE2  . GLN A 1 244 ? -38.72883 -11.23495 -6.08133  1.000 42.89989  ? 244 GLN A NE2  1 
ATOM   3685 H H    . GLN A 1 244 ? -33.64195 -12.18896 -4.03684  1.000 52.41533  ? 244 GLN A H    1 
ATOM   3686 H HA   . GLN A 1 244 ? -35.53992 -11.99311 -5.78033  1.000 52.21369  ? 244 GLN A HA   1 
ATOM   3687 H HB2  . GLN A 1 244 ? -35.97815 -12.27863 -3.49210  1.000 48.93560  ? 244 GLN A HB2  1 
ATOM   3688 H HB3  . GLN A 1 244 ? -35.53158 -10.77569 -3.23293  1.000 48.93560  ? 244 GLN A HB3  1 
ATOM   3689 H HG2  . GLN A 1 244 ? -37.84800 -10.91243 -3.25672  1.000 47.33458  ? 244 GLN A HG2  1 
ATOM   3690 H HG3  . GLN A 1 244 ? -37.35787 -10.02628 -4.48143  1.000 47.33458  ? 244 GLN A HG3  1 
ATOM   3691 H HE21 . GLN A 1 244 ? -38.68338 -10.38120 -6.17428  1.000 51.47364  ? 244 GLN A HE21 1 
ATOM   3692 H HE22 . GLN A 1 244 ? -39.16722 -11.70681 -6.65121  1.000 51.47364  ? 244 GLN A HE22 1 
ATOM   3693 N N    . ASP A 1 245 ? -33.98620 -9.24835  -5.32887  1.000 43.22081  ? 245 ASP A N    1 
ATOM   3694 C CA   . ASP A 1 245 ? -33.79342 -7.92699  -5.91366  1.000 38.01326  ? 245 ASP A CA   1 
ATOM   3695 C C    . ASP A 1 245 ? -33.46323 -8.03162  -7.39505  1.000 39.01057  ? 245 ASP A C    1 
ATOM   3696 O O    . ASP A 1 245 ? -33.93080 -7.22118  -8.20199  1.000 42.24916  ? 245 ASP A O    1 
ATOM   3697 C CB   . ASP A 1 245 ? -32.68949 -7.18673  -5.16583  1.000 44.64456  ? 245 ASP A CB   1 
ATOM   3698 C CG   . ASP A 1 245 ? -32.97154 -7.07915  -3.68605  1.000 52.30656  ? 245 ASP A CG   1 
ATOM   3699 O OD1  . ASP A 1 245 ? -32.91493 -8.11492  -2.98581  1.000 64.79171  ? 245 ASP A OD1  1 
ATOM   3700 O OD2  . ASP A 1 245 ? -33.26405 -5.95944  -3.22578  1.000 49.02062  ? 245 ASP A OD2  1 
ATOM   3701 H H    . ASP A 1 245 ? -33.40793 -9.46569  -4.73057  1.000 51.85874  ? 245 ASP A H    1 
ATOM   3702 H HA   . ASP A 1 245 ? -34.61231 -7.41497  -5.82333  1.000 45.60969  ? 245 ASP A HA   1 
ATOM   3703 H HB2  . ASP A 1 245 ? -31.85302 -7.66450  -5.27964  1.000 53.56724  ? 245 ASP A HB2  1 
ATOM   3704 H HB3  . ASP A 1 245 ? -32.61004 -6.28877  -5.52395  1.000 53.56724  ? 245 ASP A HB3  1 
ATOM   3705 N N    . HIS A 1 246 ? -32.65917 -9.02642  -7.77200  1.000 40.63558  ? 246 HIS A N    1 
ATOM   3706 C CA   . HIS A 1 246 ? -32.38177 -9.25720  -9.18502  1.000 43.22624  ? 246 HIS A CA   1 
ATOM   3707 C C    . HIS A 1 246 ? -33.64282 -9.64994  -9.94470  1.000 40.85267  ? 246 HIS A C    1 
ATOM   3708 O O    . HIS A 1 246 ? -33.80826 -9.28273  -11.11322 1.000 35.42753  ? 246 HIS A O    1 
ATOM   3709 C CB   . HIS A 1 246 ? -31.31503 -10.33886 -9.33692  1.000 35.81386  ? 246 HIS A CB   1 
ATOM   3710 C CG   . HIS A 1 246 ? -29.96871 -9.93622  -8.82384  1.000 41.93791  ? 246 HIS A CG   1 
ATOM   3711 N ND1  . HIS A 1 246 ? -29.08619 -10.83449 -8.26330  1.000 41.85333  ? 246 HIS A ND1  1 
ATOM   3712 C CD2  . HIS A 1 246 ? -29.35055 -8.73220  -8.79319  1.000 38.45627  ? 246 HIS A CD2  1 
ATOM   3713 C CE1  . HIS A 1 246 ? -27.98410 -10.20028 -7.90494  1.000 38.13193  ? 246 HIS A CE1  1 
ATOM   3714 N NE2  . HIS A 1 246 ? -28.11810 -8.92390  -8.21745  1.000 38.53934  ? 246 HIS A NE2  1 
ATOM   3715 H H    . HIS A 1 246 ? -32.26788 -9.57354  -7.23615  1.000 48.75647  ? 246 HIS A H    1 
ATOM   3716 H HA   . HIS A 1 246 ? -32.04212 -8.43488  -9.57146  1.000 51.86526  ? 246 HIS A HA   1 
ATOM   3717 H HB2  . HIS A 1 246 ? -31.59635 -11.12538 -8.84382  1.000 42.97041  ? 246 HIS A HB2  1 
ATOM   3718 H HB3  . HIS A 1 246 ? -31.22075 -10.55353 -10.27816 1.000 42.97041  ? 246 HIS A HB3  1 
ATOM   3719 H HD2  . HIS A 1 246 ? -29.69558 -7.92633  -9.10371  1.000 46.14130  ? 246 HIS A HD2  1 
ATOM   3720 H HE1  . HIS A 1 246 ? -27.24061 -10.58664 -7.50140  1.000 45.75208  ? 246 HIS A HE1  1 
ATOM   3721 H HE2  . HIS A 1 246 ? -27.52914 -8.31196  -8.08236  1.000 46.24098  ? 246 HIS A HE2  1 
ATOM   3722 N N    . VAL A 1 247 ? -34.54072 -10.40571 -9.30047  1.000 36.75801  ? 247 VAL A N    1 
ATOM   3723 C CA   . VAL A 1 247 ? -35.78598 -10.81215 -9.95033  1.000 39.19393  ? 247 VAL A CA   1 
ATOM   3724 C C    . VAL A 1 247 ? -36.65361 -9.59523  -10.25035 1.000 38.58499  ? 247 VAL A C    1 
ATOM   3725 O O    . VAL A 1 247 ? -37.23778 -9.48242  -11.33582 1.000 40.76471  ? 247 VAL A O    1 
ATOM   3726 C CB   . VAL A 1 247 ? -36.53504 -11.83498 -9.07316  1.000 36.90887  ? 247 VAL A CB   1 
ATOM   3727 C CG1  . VAL A 1 247 ? -37.85151 -12.22689 -9.71509  1.000 35.17600  ? 247 VAL A CG1  1 
ATOM   3728 C CG2  . VAL A 1 247 ? -35.67545 -13.06640 -8.83309  1.000 41.64420  ? 247 VAL A CG2  1 
ATOM   3729 H H    . VAL A 1 247 ? -34.45170 -10.69242 -8.49457  1.000 44.10338  ? 247 VAL A H    1 
ATOM   3730 H HA   . VAL A 1 247 ? -35.56728 -11.23885 -10.79354 1.000 47.02649  ? 247 VAL A HA   1 
ATOM   3731 H HB   . VAL A 1 247 ? -36.72558 -11.42526 -8.21483  1.000 44.28442  ? 247 VAL A HB   1 
ATOM   3732 H HG11 . VAL A 1 247 ? -38.21159 -12.99892 -9.25119  1.000 42.20497  ? 247 VAL A HG11 1 
ATOM   3733 H HG12 . VAL A 1 247 ? -38.46971 -11.48245 -9.64767  1.000 42.20497  ? 247 VAL A HG12 1 
ATOM   3734 H HG13 . VAL A 1 247 ? -37.69585 -12.44418 -10.64754 1.000 42.20497  ? 247 VAL A HG13 1 
ATOM   3735 H HG21 . VAL A 1 247 ? -34.76243 -12.87022 -9.09540  1.000 49.96681  ? 247 VAL A HG21 1 
ATOM   3736 H HG22 . VAL A 1 247 ? -35.70710 -13.29483 -7.89090  1.000 49.96681  ? 247 VAL A HG22 1 
ATOM   3737 H HG23 . VAL A 1 247 ? -36.02134 -13.80125 -9.36342  1.000 49.96681  ? 247 VAL A HG23 1 
ATOM   3738 N N    . ASP A 1 248 ? -36.75489 -8.66790  -9.29141  1.000 35.21267  ? 248 ASP A N    1 
ATOM   3739 C CA   . ASP A 1 248 ? -37.56538 -7.46907  -9.48826  1.000 34.30429  ? 248 ASP A CA   1 
ATOM   3740 C C    . ASP A 1 248 ? -36.98463 -6.57603  -10.57947 1.000 41.48188  ? 248 ASP A C    1 
ATOM   3741 O O    . ASP A 1 248 ? -37.72832 -6.02470  -11.39925 1.000 42.52012  ? 248 ASP A O    1 
ATOM   3742 C CB   . ASP A 1 248 ? -37.67081 -6.67940  -8.18108  1.000 37.76437  ? 248 ASP A CB   1 
ATOM   3743 C CG   . ASP A 1 248 ? -38.36939 -7.44783  -7.07265  1.000 40.02943  ? 248 ASP A CG   1 
ATOM   3744 O OD1  . ASP A 1 248 ? -38.97141 -8.50829  -7.34623  1.000 40.71507  ? 248 ASP A OD1  1 
ATOM   3745 O OD2  . ASP A 1 248 ? -38.31170 -6.97918  -5.91437  1.000 47.70832  ? 248 ASP A OD2  1 
ATOM   3746 H H    . ASP A 1 248 ? -36.36674 -8.71081  -8.52519  1.000 42.24897  ? 248 ASP A H    1 
ATOM   3747 H HA   . ASP A 1 248 ? -38.45550 -7.74675  -9.75562  1.000 41.15892  ? 248 ASP A HA   1 
ATOM   3748 H HB2  . ASP A 1 248 ? -36.77749 -6.45917  -7.87387  1.000 45.31102  ? 248 ASP A HB2  1 
ATOM   3749 H HB3  . ASP A 1 248 ? -38.17519 -5.86708  -8.34428  1.000 45.31102  ? 248 ASP A HB3  1 
ATOM   3750 N N    . ILE A 1 249 ? -35.66050 -6.39188  -10.58109 1.000 47.66324  ? 249 ILE A N    1 
ATOM   3751 C CA   . ILE A 1 249 ? -35.00982 -5.59912  -11.62132 1.000 42.84265  ? 249 ILE A CA   1 
ATOM   3752 C C    . ILE A 1 249 ? -35.33847 -6.15081  -13.00091 1.000 36.73282  ? 249 ILE A C    1 
ATOM   3753 O O    . ILE A 1 249 ? -35.44826 -5.39317  -13.97277 1.000 36.62239  ? 249 ILE A O    1 
ATOM   3754 C CB   . ILE A 1 249 ? -33.48579 -5.56146  -11.37889 1.000 47.80833  ? 249 ILE A CB   1 
ATOM   3755 C CG1  . ILE A 1 249 ? -33.16864 -4.82707  -10.07297 1.000 51.57200  ? 249 ILE A CG1  1 
ATOM   3756 C CG2  . ILE A 1 249 ? -32.76313 -4.89660  -12.54551 1.000 45.68670  ? 249 ILE A CG2  1 
ATOM   3757 C CD1  . ILE A 1 249 ? -31.72214 -4.97181  -9.61816  1.000 58.15050  ? 249 ILE A CD1  1 
ATOM   3758 H H    . ILE A 1 249 ? -35.12119 -6.71410  -9.99380  1.000 57.18966  ? 249 ILE A H    1 
ATOM   3759 H HA   . ILE A 1 249 ? -35.34647 -4.69054  -11.57584 1.000 51.40495  ? 249 ILE A HA   1 
ATOM   3760 H HB   . ILE A 1 249 ? -33.17428 -6.47726  -11.30709 1.000 57.36377  ? 249 ILE A HB   1 
ATOM   3761 H HG12 . ILE A 1 249 ? -33.34607 -3.88150  -10.19670 1.000 61.88018  ? 249 ILE A HG12 1 
ATOM   3762 H HG13 . ILE A 1 249 ? -33.73590 -5.18195  -9.37071  1.000 61.88018  ? 249 ILE A HG13 1 
ATOM   3763 H HG21 . ILE A 1 249 ? -32.82823 -5.46983  -13.32530 1.000 54.81781  ? 249 ILE A HG21 1 
ATOM   3764 H HG22 . ILE A 1 249 ? -33.18032 -4.04028  -12.72871 1.000 54.81781  ? 249 ILE A HG22 1 
ATOM   3765 H HG23 . ILE A 1 249 ? -31.83185 -4.76663  -12.30735 1.000 54.81781  ? 249 ILE A HG23 1 
ATOM   3766 H HD11 . ILE A 1 249 ? -31.16839 -4.35882  -10.12660 1.000 69.77437  ? 249 ILE A HD11 1 
ATOM   3767 H HD12 . ILE A 1 249 ? -31.66583 -4.76197  -8.67280  1.000 69.77437  ? 249 ILE A HD12 1 
ATOM   3768 H HD13 . ILE A 1 249 ? -31.43250 -5.88465  -9.77220  1.000 69.77437  ? 249 ILE A HD13 1 
ATOM   3769 N N    . LEU A 1 250 ? -35.49129 -7.46900  -13.11606 1.000 37.72888  ? 250 LEU A N    1 
ATOM   3770 C CA   . LEU A 1 250 ? -35.82371 -8.10239  -14.38633 1.000 42.67263  ? 250 LEU A CA   1 
ATOM   3771 C C    . LEU A 1 250 ? -37.30751 -8.02323  -14.72560 1.000 42.01596  ? 250 LEU A C    1 
ATOM   3772 O O    . LEU A 1 250 ? -37.71740 -8.56567  -15.75787 1.000 38.50850  ? 250 LEU A O    1 
ATOM   3773 C CB   . LEU A 1 250 ? -35.39037 -9.57140  -14.36889 1.000 34.46438  ? 250 LEU A CB   1 
ATOM   3774 C CG   . LEU A 1 250 ? -33.89019 -9.83692  -14.50674 1.000 37.68041  ? 250 LEU A CG   1 
ATOM   3775 C CD1  . LEU A 1 250 ? -33.54977 -11.23777 -14.03459 1.000 33.61768  ? 250 LEU A CD1  1 
ATOM   3776 C CD2  . LEU A 1 250 ? -33.43323 -9.64098  -15.94668 1.000 34.63321  ? 250 LEU A CD2  1 
ATOM   3777 H H    . LEU A 1 250 ? -35.40622 -8.02322  -12.46398 1.000 45.26843  ? 250 LEU A H    1 
ATOM   3778 H HA   . LEU A 1 250 ? -35.33280 -7.64792  -15.08873 1.000 51.20093  ? 250 LEU A HA   1 
ATOM   3779 H HB2  . LEU A 1 250 ? -35.67306 -9.95889  -13.52578 1.000 41.35102  ? 250 LEU A HB2  1 
ATOM   3780 H HB3  . LEU A 1 250 ? -35.82975 -10.02386 -15.10586 1.000 41.35102  ? 250 LEU A HB3  1 
ATOM   3781 H HG   . LEU A 1 250 ? -33.41234 -9.20211  -13.95034 1.000 45.21027  ? 250 LEU A HG   1 
ATOM   3782 H HD11 . LEU A 1 250 ? -33.71017 -11.29691 -13.07977 1.000 40.33498  ? 250 LEU A HD11 1 
ATOM   3783 H HD12 . LEU A 1 250 ? -34.11092 -11.87444 -14.50433 1.000 40.33498  ? 250 LEU A HD12 1 
ATOM   3784 H HD13 . LEU A 1 250 ? -32.61561 -11.41685 -14.22478 1.000 40.33498  ? 250 LEU A HD13 1 
ATOM   3785 H HD21 . LEU A 1 250 ? -32.46367 -9.65024  -15.97435 1.000 41.55363  ? 250 LEU A HD21 1 
ATOM   3786 H HD22 . LEU A 1 250 ? -33.78658 -10.36191 -16.49102 1.000 41.55363  ? 250 LEU A HD22 1 
ATOM   3787 H HD23 . LEU A 1 250 ? -33.76525 -8.78892  -16.27020 1.000 41.55363  ? 250 LEU A HD23 1 
ATOM   3788 N N    . GLY A 1 251 ? -38.11286 -7.36688  -13.89352 1.000 38.23464  ? 251 GLY A N    1 
ATOM   3789 C CA   . GLY A 1 251 ? -39.54218 -7.29770  -14.08870 1.000 43.47945  ? 251 GLY A CA   1 
ATOM   3790 C C    . GLY A 1 251 ? -39.96003 -6.76532  -15.44513 1.000 37.46572  ? 251 GLY A C    1 
ATOM   3791 O O    . GLY A 1 251 ? -40.71596 -7.40889  -16.17874 1.000 41.23049  ? 251 GLY A O    1 
ATOM   3792 H H    . GLY A 1 251 ? -37.84136 -6.94612  -13.19434 1.000 45.87533  ? 251 GLY A H    1 
ATOM   3793 H HA2  . GLY A 1 251 ? -39.91583 -8.18740  -13.99015 1.000 52.16911  ? 251 GLY A HA2  1 
ATOM   3794 H HA3  . GLY A 1 251 ? -39.92379 -6.71805  -13.41100 1.000 52.16911  ? 251 GLY A HA3  1 
ATOM   3795 N N    . PRO A 1 252 ? -39.49529 -5.56314  -15.79636 1.000 36.73670  ? 252 PRO A N    1 
ATOM   3796 C CA   . PRO A 1 252 ? -39.85335 -5.00145  -17.11274 1.000 34.93794  ? 252 PRO A CA   1 
ATOM   3797 C C    . PRO A 1 252 ? -39.60524 -5.96133  -18.26755 1.000 37.77357  ? 252 PRO A C    1 
ATOM   3798 O O    . PRO A 1 252 ? -40.47564 -6.12346  -19.13254 1.000 37.43937  ? 252 PRO A O    1 
ATOM   3799 C CB   . PRO A 1 252 ? -38.97458 -3.74555  -17.19669 1.000 36.78684  ? 252 PRO A CB   1 
ATOM   3800 C CG   . PRO A 1 252 ? -38.73900 -3.35423  -15.76940 1.000 41.52687  ? 252 PRO A CG   1 
ATOM   3801 C CD   . PRO A 1 252 ? -38.67058 -4.64004  -14.99666 1.000 41.26580  ? 252 PRO A CD   1 
ATOM   3802 H HA   . PRO A 1 252 ? -40.78704 -4.73855  -17.11328 1.000 41.91930  ? 252 PRO A HA   1 
ATOM   3803 H HB2  . PRO A 1 252 ? -38.13927 -3.95421  -17.64347 1.000 44.13798  ? 252 PRO A HB2  1 
ATOM   3804 H HB3  . PRO A 1 252 ? -39.44210 -3.04490  -17.67774 1.000 44.13798  ? 252 PRO A HB3  1 
ATOM   3805 H HG2  . PRO A 1 252 ? -37.90409 -2.86567  -15.69778 1.000 49.82602  ? 252 PRO A HG2  1 
ATOM   3806 H HG3  . PRO A 1 252 ? -39.47348 -2.80373  -15.45574 1.000 49.82602  ? 252 PRO A HG3  1 
ATOM   3807 H HD2  . PRO A 1 252 ? -37.75620 -4.95821  -14.93686 1.000 49.51274  ? 252 PRO A HD2  1 
ATOM   3808 H HD3  . PRO A 1 252 ? -39.04174 -4.52818  -14.10749 1.000 49.51274  ? 252 PRO A HD3  1 
ATOM   3809 N N    . LEU A 1 253 ? -38.44327 -6.62086  -18.29570 1.000 37.57858  ? 253 LEU A N    1 
ATOM   3810 C CA   . LEU A 1 253 ? -38.16925 -7.58212  -19.36001 1.000 45.92441  ? 253 LEU A CA   1 
ATOM   3811 C C    . LEU A 1 253 ? -39.10479 -8.78117  -19.27037 1.000 41.75966  ? 253 LEU A C    1 
ATOM   3812 O O    . LEU A 1 253 ? -39.53270 -9.32065  -20.29746 1.000 42.34905  ? 253 LEU A O    1 
ATOM   3813 C CB   . LEU A 1 253 ? -36.70910 -8.03601  -19.30165 1.000 31.94955  ? 253 LEU A CB   1 
ATOM   3814 C CG   . LEU A 1 253 ? -35.65737 -6.95711  -19.56669 1.000 39.68274  ? 253 LEU A CG   1 
ATOM   3815 C CD1  . LEU A 1 253 ? -34.24350 -7.51119  -19.39004 1.000 35.42469  ? 253 LEU A CD1  1 
ATOM   3816 C CD2  . LEU A 1 253 ? -35.82893 -6.36395  -20.95380 1.000 43.06947  ? 253 LEU A CD2  1 
ATOM   3817 H H    . LEU A 1 253 ? -37.81025 -6.53040  -17.72064 1.000 45.08806  ? 253 LEU A H    1 
ATOM   3818 H HA   . LEU A 1 253 ? -38.31224 -7.14817  -20.21567 1.000 55.10306  ? 253 LEU A HA   1 
ATOM   3819 H HB2  . LEU A 1 253 ? -36.53850 -8.39108  -18.41525 1.000 38.33323  ? 253 LEU A HB2  1 
ATOM   3820 H HB3  . LEU A 1 253 ? -36.58184 -8.73007  -19.96722 1.000 38.33323  ? 253 LEU A HB3  1 
ATOM   3821 H HG   . LEU A 1 253 ? -35.77941 -6.24561  -18.91879 1.000 47.61306  ? 253 LEU A HG   1 
ATOM   3822 H HD11 . LEU A 1 253 ? -34.13169 -7.80464  -18.47228 1.000 42.50340  ? 253 LEU A HD11 1 
ATOM   3823 H HD12 . LEU A 1 253 ? -34.12002 -8.26001  -19.99412 1.000 42.50340  ? 253 LEU A HD12 1 
ATOM   3824 H HD13 . LEU A 1 253 ? -33.60262 -6.81228  -19.59426 1.000 42.50340  ? 253 LEU A HD13 1 
ATOM   3825 H HD21 . LEU A 1 253 ? -35.10553 -5.74005  -21.12216 1.000 51.67713  ? 253 LEU A HD21 1 
ATOM   3826 H HD22 . LEU A 1 253 ? -35.80751 -7.07965  -21.60818 1.000 51.67713  ? 253 LEU A HD22 1 
ATOM   3827 H HD23 . LEU A 1 253 ? -36.68081 -5.90202  -20.99659 1.000 51.67713  ? 253 LEU A HD23 1 
ATOM   3828 N N    . SER A 1 254 ? -39.43398 -9.21096  -18.05090 1.000 39.21626  ? 254 SER A N    1 
ATOM   3829 C CA   A SER A 1 254 ? -40.34443 -10.33894 -17.88423 0.710 43.06542  ? 254 SER A CA   1 
ATOM   3830 C CA   B SER A 1 254 ? -40.34127 -10.34171 -17.89364 0.290 43.11243  ? 254 SER A CA   1 
ATOM   3831 C C    . SER A 1 254 ? -41.74026 -10.00337 -18.39716 1.000 39.34187  ? 254 SER A C    1 
ATOM   3832 O O    . SER A 1 254 ? -42.38968 -10.83645 -19.03827 1.000 44.83483  ? 254 SER A O    1 
ATOM   3833 C CB   A SER A 1 254 ? -40.39850 -10.74798 -16.41177 0.710 41.80461  ? 254 SER A CB   1 
ATOM   3834 C CB   B SER A 1 254 ? -40.38859 -10.77594 -16.42897 0.290 42.15741  ? 254 SER A CB   1 
ATOM   3835 O OG   A SER A 1 254 ? -41.24295 -11.86823 -16.21811 0.710 40.82858  ? 254 SER A OG   1 
ATOM   3836 O OG   B SER A 1 254 ? -40.97143 -9.77290  -15.61679 0.290 39.17921  ? 254 SER A OG   1 
ATOM   3837 H H    A SER A 1 254 ? -39.14733 -8.87075  -17.31490 0.710 47.05328  ? 254 SER A H    1 
ATOM   3838 H H    B SER A 1 254 ? -39.15037 -8.87070  -17.31375 0.290 47.05328  ? 254 SER A H    1 
ATOM   3839 H HA   A SER A 1 254 ? -40.01000 -11.09155 -18.39670 0.710 51.67227  ? 254 SER A HA   1 
ATOM   3840 H HA   B SER A 1 254 ? -40.00563 -11.08596 -18.41741 0.290 51.72868  ? 254 SER A HA   1 
ATOM   3841 H HB2  A SER A 1 254 ? -39.50302 -10.97542 -16.11633 0.710 50.15931  ? 254 SER A HB2  1 
ATOM   3842 H HB2  B SER A 1 254 ? -40.91845 -11.58532 -16.35791 0.290 50.58266  ? 254 SER A HB2  1 
ATOM   3843 H HB3  A SER A 1 254 ? -40.74040 -10.00387 -15.89188 0.710 50.15931  ? 254 SER A HB3  1 
ATOM   3844 H HB3  B SER A 1 254 ? -39.48407 -10.94346 -16.12127 0.290 50.58266  ? 254 SER A HB3  1 
ATOM   3845 H HG   A SER A 1 254 ? -40.88490 -12.55685 -16.53937 0.710 48.98806  ? 254 SER A HG   1 
ATOM   3846 H HG   B SER A 1 254 ? -41.01953 -10.03915 -14.82156 0.290 47.00883  ? 254 SER A HG   1 
ATOM   3847 N N    . ALA A 1 255 ? -42.21906 -8.78532  -18.12748 1.000 42.07719  ? 255 ALA A N    1 
ATOM   3848 C CA   . ALA A 1 255 ? -43.56820 -8.40507  -18.53518 1.000 44.88268  ? 255 ALA A CA   1 
ATOM   3849 C C    . ALA A 1 255 ? -43.65409 -8.08474  -20.02220 1.000 49.20506  ? 255 ALA A C    1 
ATOM   3850 O O    . ALA A 1 255 ? -44.73429 -8.19560  -20.61353 1.000 48.00189  ? 255 ALA A O    1 
ATOM   3851 C CB   . ALA A 1 255 ? -44.04806 -7.20277  -17.71842 1.000 37.45252  ? 255 ALA A CB   1 
ATOM   3852 H H    . ALA A 1 255 ? -41.78541 -8.16859  -17.71373 1.000 50.48640  ? 255 ALA A H    1 
ATOM   3853 H HA   . ALA A 1 255 ? -44.16278 -9.14992  -18.35472 1.000 53.85299  ? 255 ALA A HA   1 
ATOM   3854 H HB1  . ALA A 1 255 ? -44.98139 -7.03474  -17.92229 1.000 44.93680  ? 255 ALA A HB1  1 
ATOM   3855 H HB2  . ALA A 1 255 ? -43.94624 -7.40136  -16.77444 1.000 44.93680  ? 255 ALA A HB2  1 
ATOM   3856 H HB3  . ALA A 1 255 ? -43.51357 -6.42805  -17.95298 1.000 44.93680  ? 255 ALA A HB3  1 
ATOM   3857 N N    . GLN A 1 256 ? -42.54310 -7.68083  -20.64021 1.000 45.96960  ? 256 GLN A N    1 
ATOM   3858 C CA   . GLN A 1 256 ? -42.54619 -7.45398  -22.08126 1.000 45.65039  ? 256 GLN A CA   1 
ATOM   3859 C C    . GLN A 1 256 ? -42.70106 -8.77017  -22.83639 1.000 43.68608  ? 256 GLN A C    1 
ATOM   3860 O O    . GLN A 1 256 ? -43.51164 -8.87531  -23.76412 1.000 54.48313  ? 256 GLN A O    1 
ATOM   3861 C CB   . GLN A 1 256 ? -41.26028 -6.73923  -22.50064 1.000 56.47729  ? 256 GLN A CB   1 
ATOM   3862 C CG   . GLN A 1 256 ? -41.45250 -5.66885  -23.56694 1.000 66.88058  ? 256 GLN A CG   1 
ATOM   3863 C CD   . GLN A 1 256 ? -40.13770 -5.19165  -24.16104 1.000 56.94577  ? 256 GLN A CD   1 
ATOM   3864 O OE1  . GLN A 1 256 ? -39.25740 -4.71039  -23.44756 1.000 65.89220  ? 256 GLN A OE1  1 
ATOM   3865 N NE2  . GLN A 1 256 ? -39.99713 -5.33154  -25.47458 1.000 58.29290  ? 256 GLN A NE2  1 
ATOM   3866 H H    . GLN A 1 256 ? -41.78893 -7.53397  -20.25387 1.000 55.15729  ? 256 GLN A H    1 
ATOM   3867 H HA   . GLN A 1 256 ? -43.29555 -6.88211  -22.31004 1.000 54.77424  ? 256 GLN A HA   1 
ATOM   3868 H HB2  . GLN A 1 256 ? -40.87677 -6.30975  -21.72001 1.000 67.76652  ? 256 GLN A HB2  1 
ATOM   3869 H HB3  . GLN A 1 256 ? -40.64203 -7.39765  -22.85438 1.000 67.76652  ? 256 GLN A HB3  1 
ATOM   3870 H HG2  . GLN A 1 256 ? -41.99282 -6.03194  -24.28606 1.000 80.25046  ? 256 GLN A HG2  1 
ATOM   3871 H HG3  . GLN A 1 256 ? -41.89829 -4.90387  -23.17073 1.000 80.25046  ? 256 GLN A HG3  1 
ATOM   3872 H HE21 . GLN A 1 256 ? -40.63202 -5.67696  -25.94062 1.000 69.94525  ? 256 GLN A HE21 1 
ATOM   3873 H HE22 . GLN A 1 256 ? -39.27122 -5.07667  -25.85891 1.000 69.94525  ? 256 GLN A HE22 1 
ATOM   3874 N N    . THR A 1 257 ? -41.94650 -9.79289  -22.43843 1.000 46.16889  ? 257 THR A N    1 
ATOM   3875 C CA   . THR A 1 257 ? -41.91535 -11.06193 -23.15356 1.000 51.83714  ? 257 THR A CA   1 
ATOM   3876 C C    . THR A 1 257 ? -42.89320 -12.09466 -22.60340 1.000 45.30335  ? 257 THR A C    1 
ATOM   3877 O O    . THR A 1 257 ? -42.99261 -13.19010 -23.16504 1.000 48.13465  ? 257 THR A O    1 
ATOM   3878 C CB   . THR A 1 257 ? -40.49751 -11.64490 -23.12195 1.000 38.55839  ? 257 THR A CB   1 
ATOM   3879 O OG1  . THR A 1 257 ? -40.17465 -12.05896 -21.78749 1.000 40.59886  ? 257 THR A OG1  1 
ATOM   3880 C CG2  . THR A 1 257 ? -39.48812 -10.60471 -23.58741 1.000 43.93863  ? 257 THR A CG2  1 
ATOM   3881 H H    . THR A 1 257 ? -41.43676 -9.77351  -21.74605 1.000 55.39644  ? 257 THR A H    1 
ATOM   3882 H HA   . THR A 1 257 ? -42.15810 -10.89270 -24.07732 1.000 62.19834  ? 257 THR A HA   1 
ATOM   3883 H HB   . THR A 1 257 ? -40.44743 -12.41046 -23.71550 1.000 46.26384  ? 257 THR A HB   1 
ATOM   3884 H HG1  . THR A 1 257 ? -39.43206 -12.45152 -21.78023 1.000 48.71241  ? 257 THR A HG1  1 
ATOM   3885 H HG21 . THR A 1 257 ? -39.92146 -9.95724  -24.16524 1.000 52.72013  ? 257 THR A HG21 1 
ATOM   3886 H HG22 . THR A 1 257 ? -39.11197 -10.14188 -22.82243 1.000 52.72013  ? 257 THR A HG22 1 
ATOM   3887 H HG23 . THR A 1 257 ? -38.77101 -11.03497 -24.07886 1.000 52.72013  ? 257 THR A HG23 1 
ATOM   3888 N N    . GLY A 1 258 ? -43.61684 -11.78218 -21.53166 1.000 40.63771  ? 258 GLY A N    1 
ATOM   3889 C CA   . GLY A 1 258 ? -44.52301 -12.75547 -20.95388 1.000 39.70530  ? 258 GLY A CA   1 
ATOM   3890 C C    . GLY A 1 258 ? -43.85115 -14.02795 -20.49271 1.000 49.22519  ? 258 GLY A C    1 
ATOM   3891 O O    . GLY A 1 258 ? -44.50451 -15.07370 -20.41334 1.000 52.01348  ? 258 GLY A O    1 
ATOM   3892 H H    . GLY A 1 258 ? -43.59866 -11.02261 -21.12878 1.000 48.75902  ? 258 GLY A H    1 
ATOM   3893 H HA2  . GLY A 1 258 ? -44.96496 -12.35653 -20.18809 1.000 47.64013  ? 258 GLY A HA2  1 
ATOM   3894 H HA3  . GLY A 1 258 ? -45.19119 -12.99333 -21.61559 1.000 47.64013  ? 258 GLY A HA3  1 
ATOM   3895 N N    . ILE A 1 259 ? -42.55674 -13.97158 -20.18305 1.000 46.23693  ? 259 ILE A N    1 
ATOM   3896 C CA   . ILE A 1 259 ? -41.79825 -15.12740 -19.71760 1.000 43.98258  ? 259 ILE A CA   1 
ATOM   3897 C C    . ILE A 1 259 ? -41.41324 -14.87666 -18.26667 1.000 44.74185  ? 259 ILE A C    1 
ATOM   3898 O O    . ILE A 1 259 ? -40.61354 -13.97883 -17.97175 1.000 44.22632  ? 259 ILE A O    1 
ATOM   3899 C CB   . ILE A 1 259 ? -40.55169 -15.38704 -20.57460 1.000 47.14004  ? 259 ILE A CB   1 
ATOM   3900 C CG1  . ILE A 1 259 ? -40.94364 -15.64675 -22.03128 1.000 44.48896  ? 259 ILE A CG1  1 
ATOM   3901 C CG2  . ILE A 1 259 ? -39.76174 -16.57155 -20.00270 1.000 44.12101  ? 259 ILE A CG2  1 
ATOM   3902 C CD1  . ILE A 1 259 ? -39.77355 -15.57061 -23.00819 1.000 45.84358  ? 259 ILE A CD1  1 
ATOM   3903 H H    . ILE A 1 259 ? -42.08530 -13.25432 -20.23671 1.000 55.47808  ? 259 ILE A H    1 
ATOM   3904 H HA   . ILE A 1 259 ? -42.36908 -15.91063 -19.75748 1.000 52.77287  ? 259 ILE A HA   1 
ATOM   3905 H HB   . ILE A 1 259 ? -39.98935 -14.59698 -20.55269 1.000 56.56182  ? 259 ILE A HB   1 
ATOM   3906 H HG12 . ILE A 1 259 ? -41.32643 -16.53558 -22.09715 1.000 53.38052  ? 259 ILE A HG12 1 
ATOM   3907 H HG13 . ILE A 1 259 ? -41.59762 -14.98306 -22.30097 1.000 53.38052  ? 259 ILE A HG13 1 
ATOM   3908 H HG21 . ILE A 1 259 ? -40.38263 -17.27255 -19.74971 1.000 52.93898  ? 259 ILE A HG21 1 
ATOM   3909 H HG22 . ILE A 1 259 ? -39.15026 -16.89998 -20.68029 1.000 52.93898  ? 259 ILE A HG22 1 
ATOM   3910 H HG23 . ILE A 1 259 ? -39.26454 -16.27353 -19.22495 1.000 52.93898  ? 259 ILE A HG23 1 
ATOM   3911 H HD11 . ILE A 1 259 ? -38.96963 -15.88091 -22.56285 1.000 55.00607  ? 259 ILE A HD11 1 
ATOM   3912 H HD12 . ILE A 1 259 ? -39.96511 -16.13316 -23.77483 1.000 55.00607  ? 259 ILE A HD12 1 
ATOM   3913 H HD13 . ILE A 1 259 ? -39.65957 -14.65049 -23.29332 1.000 55.00607  ? 259 ILE A HD13 1 
ATOM   3914 N N    . ALA A 1 260 ? -41.96726 -15.67988 -17.36175 1.000 42.40926  ? 260 ALA A N    1 
ATOM   3915 C CA   . ALA A 1 260 ? -41.65178 -15.53716 -15.94813 1.000 47.88951  ? 260 ALA A CA   1 
ATOM   3916 C C    . ALA A 1 260 ? -40.15625 -15.70497 -15.72450 1.000 39.75470  ? 260 ALA A C    1 
ATOM   3917 O O    . ALA A 1 260 ? -39.51479 -16.57051 -16.32450 1.000 43.72127  ? 260 ALA A O    1 
ATOM   3918 C CB   . ALA A 1 260 ? -42.42604 -16.56379 -15.12126 1.000 44.79575  ? 260 ALA A CB   1 
ATOM   3919 H H    . ALA A 1 260 ? -42.52446 -16.31005 -17.54069 1.000 50.88489  ? 260 ALA A H    1 
ATOM   3920 H HA   . ALA A 1 260 ? -41.91311 -14.65287 -15.64707 1.000 57.46118  ? 260 ALA A HA   1 
ATOM   3921 H HB1  . ALA A 1 260 ? -42.16617 -16.48035 -14.19045 1.000 53.74867  ? 260 ALA A HB1  1 
ATOM   3922 H HB2  . ALA A 1 260 ? -43.37630 -16.39364 -15.21591 1.000 53.74867  ? 260 ALA A HB2  1 
ATOM   3923 H HB3  . ALA A 1 260 ? -42.21547 -17.45360 -15.44499 1.000 53.74867  ? 260 ALA A HB3  1 
ATOM   3924 N N    . VAL A 1 261 ? -39.60129 -14.86419 -14.85017 1.000 44.68126  ? 261 VAL A N    1 
ATOM   3925 C CA   . VAL A 1 261 ? -38.16441 -14.89903 -14.59071 1.000 39.91257  ? 261 VAL A CA   1 
ATOM   3926 C C    . VAL A 1 261 ? -37.72485 -16.30421 -14.20218 1.000 41.93049  ? 261 VAL A C    1 
ATOM   3927 O O    . VAL A 1 261 ? -36.70589 -16.80894 -14.68891 1.000 42.31969  ? 261 VAL A O    1 
ATOM   3928 C CB   . VAL A 1 261 ? -37.79765 -13.86555 -13.50867 1.000 37.54000  ? 261 VAL A CB   1 
ATOM   3929 C CG1  . VAL A 1 261 ? -36.35454 -14.03874 -13.06146 1.000 33.73969  ? 261 VAL A CG1  1 
ATOM   3930 C CG2  . VAL A 1 261 ? -38.02723 -12.45522 -14.03720 1.000 36.33879  ? 261 VAL A CG2  1 
ATOM   3931 H H    . VAL A 1 261 ? -40.03047 -14.27077 -14.39933 1.000 53.61129  ? 261 VAL A H    1 
ATOM   3932 H HA   . VAL A 1 261 ? -37.69547 -14.65939 -15.40530 1.000 47.88885  ? 261 VAL A HA   1 
ATOM   3933 H HB   . VAL A 1 261 ? -38.36620 -14.00440 -12.73513 1.000 45.04178  ? 261 VAL A HB   1 
ATOM   3934 H HG11 . VAL A 1 261 ? -36.10741 -13.29079 -12.49542 1.000 40.48140  ? 261 VAL A HG11 1 
ATOM   3935 H HG12 . VAL A 1 261 ? -36.27489 -14.86891 -12.56610 1.000 40.48140  ? 261 VAL A HG12 1 
ATOM   3936 H HG13 . VAL A 1 261 ? -35.78226 -14.06441 -13.84423 1.000 40.48140  ? 261 VAL A HG13 1 
ATOM   3937 H HG21 . VAL A 1 261 ? -38.34174 -11.89339 -13.31171 1.000 43.60032  ? 261 VAL A HG21 1 
ATOM   3938 H HG22 . VAL A 1 261 ? -37.19094 -12.10846 -14.38546 1.000 43.60032  ? 261 VAL A HG22 1 
ATOM   3939 H HG23 . VAL A 1 261 ? -38.69177 -12.48679 -14.74310 1.000 43.60032  ? 261 VAL A HG23 1 
ATOM   3940 N N    . LEU A 1 262 ? -38.48737 -16.96543 -13.32895 1.000 48.41885  ? 262 LEU A N    1 
ATOM   3941 C CA   . LEU A 1 262 ? -38.10829 -18.31444 -12.92191 1.000 51.92980  ? 262 LEU A CA   1 
ATOM   3942 C C    . LEU A 1 262 ? -38.22085 -19.30291 -14.07594 1.000 41.99036  ? 262 LEU A C    1 
ATOM   3943 O O    . LEU A 1 262 ? -37.49652 -20.30360 -14.10066 1.000 46.21204  ? 262 LEU A O    1 
ATOM   3944 C CB   . LEU A 1 262 ? -38.95803 -18.77495 -11.73960 1.000 43.16989  ? 262 LEU A CB   1 
ATOM   3945 C CG   . LEU A 1 262 ? -38.50974 -18.28072 -10.36241 1.000 42.39482  ? 262 LEU A CG   1 
ATOM   3946 C CD1  . LEU A 1 262 ? -39.39513 -18.89642 -9.29044  1.000 46.90581  ? 262 LEU A CD1  1 
ATOM   3947 C CD2  . LEU A 1 262 ? -37.03938 -18.60097 -10.09599 1.000 48.83559  ? 262 LEU A CD2  1 
ATOM   3948 H H    . LEU A 1 262 ? -39.20750 -16.66316 -12.96890 1.000 58.09639  ? 262 LEU A H    1 
ATOM   3949 H HA   . LEU A 1 262 ? -37.18340 -18.29884 -12.62996 1.000 62.30953  ? 262 LEU A HA   1 
ATOM   3950 H HB2  . LEU A 1 262 ? -39.86492 -18.45955 -11.87732 1.000 51.79764  ? 262 LEU A HB2  1 
ATOM   3951 H HB3  . LEU A 1 262 ? -38.94399 -19.74456 -11.71594 1.000 51.79764  ? 262 LEU A HB3  1 
ATOM   3952 H HG   . LEU A 1 262 ? -38.59590 -17.31504 -10.33184 1.000 50.86756  ? 262 LEU A HG   1 
ATOM   3953 H HD11 . LEU A 1 262 ? -39.64068 -18.20972 -8.65088  1.000 56.28074  ? 262 LEU A HD11 1 
ATOM   3954 H HD12 . LEU A 1 262 ? -40.19171 -19.25899 -9.70866  1.000 56.28074  ? 262 LEU A HD12 1 
ATOM   3955 H HD13 . LEU A 1 262 ? -38.90465 -19.60417 -8.84389  1.000 56.28074  ? 262 LEU A HD13 1 
ATOM   3956 H HD21 . LEU A 1 262 ? -36.48556 -17.97923 -10.59361 1.000 58.59648  ? 262 LEU A HD21 1 
ATOM   3957 H HD22 . LEU A 1 262 ? -36.86408 -18.51286 -9.14604  1.000 58.59648  ? 262 LEU A HD22 1 
ATOM   3958 H HD23 . LEU A 1 262 ? -36.85696 -19.50935 -10.38316 1.000 58.59648  ? 262 LEU A HD23 1 
ATOM   3959 N N    . ASP A 1 263 ? -39.11193 -19.04796 -15.03634 1.000 41.11562  ? 263 ASP A N    1 
ATOM   3960 C CA   . ASP A 1 263 ? -39.12142 -19.86042 -16.24803 1.000 44.56256  ? 263 ASP A CA   1 
ATOM   3961 C C    . ASP A 1 263 ? -37.82589 -19.67478 -17.02858 1.000 43.67941  ? 263 ASP A C    1 
ATOM   3962 O O    . ASP A 1 263 ? -37.23555 -20.64891 -17.51069 1.000 47.17039  ? 263 ASP A O    1 
ATOM   3963 C CB   . ASP A 1 263 ? -40.32841 -19.50717 -17.12010 1.000 49.04886  ? 263 ASP A CB   1 
ATOM   3964 C CG   . ASP A 1 263 ? -41.65075 -19.92413 -16.49349 1.000 60.00121  ? 263 ASP A CG   1 
ATOM   3965 O OD1  . ASP A 1 263 ? -41.64173 -20.77543 -15.57802 1.000 52.65425  ? 263 ASP A OD1  1 
ATOM   3966 O OD2  . ASP A 1 263 ? -42.70308 -19.40356 -16.92595 1.000 73.90679  ? 263 ASP A OD2  1 
ATOM   3967 H H    . ASP A 1 263 ? -39.70553 -18.42624 -15.01008 1.000 49.33252  ? 263 ASP A H    1 
ATOM   3968 H HA   . ASP A 1 263 ? -39.20278 -20.79457 -15.99973 1.000 53.46884  ? 263 ASP A HA   1 
ATOM   3969 H HB2  . ASP A 1 263 ? -40.35033 -18.54688 -17.25522 1.000 58.85240  ? 263 ASP A HB2  1 
ATOM   3970 H HB3  . ASP A 1 263 ? -40.24501 -19.96048 -17.97359 1.000 58.85240  ? 263 ASP A HB3  1 
ATOM   3971 N N    . MET A 1 264 ? -37.35968 -18.42828 -17.15028 1.000 46.07170  ? 264 MET A N    1 
ATOM   3972 C CA   . MET A 1 264 ? -36.10196 -18.17715 -17.84612 1.000 46.28263  ? 264 MET A CA   1 
ATOM   3973 C C    . MET A 1 264 ? -34.92564 -18.77223 -17.08119 1.000 41.72506  ? 264 MET A C    1 
ATOM   3974 O O    . MET A 1 264 ? -33.96086 -19.24897 -17.68999 1.000 38.16683  ? 264 MET A O    1 
ATOM   3975 C CB   . MET A 1 264 ? -35.90623 -16.67420 -18.05226 1.000 39.41224  ? 264 MET A CB   1 
ATOM   3976 C CG   . MET A 1 264 ? -34.69900 -16.32094 -18.90825 1.000 42.80665  ? 264 MET A CG   1 
ATOM   3977 S SD   . MET A 1 264 ? -34.90308 -16.81151 -20.63379 1.000 45.50829  ? 264 MET A SD   1 
ATOM   3978 C CE   . MET A 1 264 ? -35.82668 -15.41502 -21.26874 1.000 42.04457  ? 264 MET A CE   1 
ATOM   3979 H H    . MET A 1 264 ? -37.74732 -17.72454 -16.84355 1.000 55.27981  ? 264 MET A H    1 
ATOM   3980 H HA   . MET A 1 264 ? -36.14521 -18.58998 -18.72282 1.000 55.53293  ? 264 MET A HA   1 
ATOM   3981 H HB2  . MET A 1 264 ? -36.69391 -16.31496 -18.48976 1.000 47.28846  ? 264 MET A HB2  1 
ATOM   3982 H HB3  . MET A 1 264 ? -35.78726 -16.25422 -17.18603 1.000 47.28846  ? 264 MET A HB3  1 
ATOM   3983 H HG2  . MET A 1 264 ? -34.56305 -15.36085 -18.88289 1.000 51.36175  ? 264 MET A HG2  1 
ATOM   3984 H HG3  . MET A 1 264 ? -33.91777 -16.77604 -18.55688 1.000 51.36175  ? 264 MET A HG3  1 
ATOM   3985 H HE1  . MET A 1 264 ? -35.34029 -14.59909 -21.07233 1.000 50.44725  ? 264 MET A HE1  1 
ATOM   3986 H HE2  . MET A 1 264 ? -35.93099 -15.51519 -22.22790 1.000 50.44725  ? 264 MET A HE2  1 
ATOM   3987 H HE3  . MET A 1 264 ? -36.69744 -15.39193 -20.84195 1.000 50.44725  ? 264 MET A HE3  1 
ATOM   3988 N N    . CYS A 1 265 ? -34.98487 -18.75126 -15.74655 1.000 43.79810  ? 265 CYS A N    1 
ATOM   3989 C CA   . CYS A 1 265 ? -33.93898 -19.38873 -14.95324 1.000 43.89463  ? 265 CYS A CA   1 
ATOM   3990 C C    . CYS A 1 265 ? -33.82435 -20.86994 -15.29040 1.000 47.16638  ? 265 CYS A C    1 
ATOM   3991 O O    . CYS A 1 265 ? -32.71886 -21.42337 -15.32478 1.000 50.65876  ? 265 CYS A O    1 
ATOM   3992 C CB   . CYS A 1 265 ? -34.21862 -19.20635 -13.46085 1.000 49.33508  ? 265 CYS A CB   1 
ATOM   3993 S SG   . CYS A 1 265 ? -34.00556 -17.52659 -12.83804 1.000 47.13296  ? 265 CYS A SG   1 
ATOM   3994 H H    . CYS A 1 265 ? -35.60966 -18.38070 -15.28621 1.000 52.55149  ? 265 CYS A H    1 
ATOM   3995 H HA   . CYS A 1 265 ? -33.09229 -18.96037 -15.15453 1.000 52.66733  ? 265 CYS A HA   1 
ATOM   3996 H HB2  . CYS A 1 265 ? -35.13725 -19.46536 -13.28781 1.000 59.19587  ? 265 CYS A HB2  1 
ATOM   3997 H HB3  . CYS A 1 265 ? -33.61333 -19.77873 -12.96397 1.000 59.19587  ? 265 CYS A HB3  1 
ATOM   3998 H HG   . CYS A 1 265 ? -34.88610 -16.83514 -13.26995 1.000 56.55333  ? 265 CYS A HG   1 
ATOM   3999 N N    . ALA A 1 266 ? -34.96020 -21.52894 -15.53996 1.000 53.73091  ? 266 ALA A N    1 
ATOM   4000 C CA   . ALA A 1 266 ? -34.93554 -22.94089 -15.90776 1.000 45.04257  ? 266 ALA A CA   1 
ATOM   4001 C C    . ALA A 1 266 ? -34.24584 -23.14945 -17.24942 1.000 45.31733  ? 266 ALA A C    1 
ATOM   4002 O O    . ALA A 1 266 ? -33.47160 -24.09915 -17.41296 1.000 53.53451  ? 266 ALA A O    1 
ATOM   4003 C CB   . ALA A 1 266 ? -36.35805 -23.49897 -15.94497 1.000 51.86330  ? 266 ALA A CB   1 
ATOM   4004 H H    . ALA A 1 266 ? -35.74705 -21.18383 -15.50307 1.000 64.47087  ? 266 ALA A H    1 
ATOM   4005 H HA   . ALA A 1 266 ? -34.43822 -23.42982 -15.23358 1.000 54.04485  ? 266 ALA A HA   1 
ATOM   4006 H HB1  . ALA A 1 266 ? -36.32962 -24.41524 -16.26206 1.000 62.22973  ? 266 ALA A HB1  1 
ATOM   4007 H HB2  . ALA A 1 266 ? -36.73217 -23.46995 -15.05050 1.000 62.22973  ? 266 ALA A HB2  1 
ATOM   4008 H HB3  . ALA A 1 266 ? -36.89406 -22.95763 -16.54543 1.000 62.22973  ? 266 ALA A HB3  1 
ATOM   4009 N N    . SER A 1 267 ? -34.52197 -22.28132 -18.22590 1.000 45.98804  ? 267 SER A N    1 
ATOM   4010 C CA   . SER A 1 267 ? -33.78776 -22.33830 -19.48578 1.000 51.50796  ? 267 SER A CA   1 
ATOM   4011 C C    . SER A 1 267 ? -32.28901 -22.20255 -19.24915 1.000 46.41463  ? 267 SER A C    1 
ATOM   4012 O O    . SER A 1 267 ? -31.48962 -22.95014 -19.82450 1.000 49.21245  ? 267 SER A O    1 
ATOM   4013 C CB   . SER A 1 267 ? -34.27988 -21.24349 -20.43268 1.000 44.24909  ? 267 SER A CB   1 
ATOM   4014 O OG   . SER A 1 267 ? -35.60988 -21.49328 -20.84789 1.000 50.95223  ? 267 SER A OG   1 
ATOM   4015 H H    . SER A 1 267 ? -35.11800 -21.66283 -18.18331 1.000 55.17942  ? 267 SER A H    1 
ATOM   4016 H HA   . SER A 1 267 ? -33.95424 -23.19581 -19.90751 1.000 61.80332  ? 267 SER A HA   1 
ATOM   4017 H HB2  . SER A 1 267 ? -34.24839 -20.39051 -19.97187 1.000 53.09268  ? 267 SER A HB2  1 
ATOM   4018 H HB3  . SER A 1 267 ? -33.70493 -21.22014 -21.21356 1.000 53.09268  ? 267 SER A HB3  1 
ATOM   4019 H HG   . SER A 1 267 ? -36.10117 -21.61870 -20.17819 1.000 61.13645  ? 267 SER A HG   1 
ATOM   4020 N N    . LEU A 1 268 ? -31.88899 -21.25709 -18.39763 1.000 42.78940  ? 268 LEU A N    1 
ATOM   4021 C CA   . LEU A 1 268 ? -30.46992 -21.07781 -18.11454 1.000 44.20698  ? 268 LEU A CA   1 
ATOM   4022 C C    . LEU A 1 268 ? -29.89372 -22.30472 -17.42262 1.000 47.03225  ? 268 LEU A C    1 
ATOM   4023 O O    . LEU A 1 268 ? -28.78992 -22.75172 -17.75504 1.000 48.43658  ? 268 LEU A O    1 
ATOM   4024 C CB   . LEU A 1 268 ? -30.26573 -19.82525 -17.26343 1.000 42.35519  ? 268 LEU A CB   1 
ATOM   4025 C CG   . LEU A 1 268 ? -28.83576 -19.45352 -16.87065 1.000 40.12156  ? 268 LEU A CG   1 
ATOM   4026 C CD1  . LEU A 1 268 ? -27.88709 -19.57636 -18.04832 1.000 38.74826  ? 268 LEU A CD1  1 
ATOM   4027 C CD2  . LEU A 1 268 ? -28.80931 -18.03440 -16.31157 1.000 43.48211  ? 268 LEU A CD2  1 
ATOM   4028 H H    . LEU A 1 268 ? -32.41086 -20.71675 -17.97895 1.000 51.34105  ? 268 LEU A H    1 
ATOM   4029 H HA   . LEU A 1 268 ? -29.99026 -20.95286 -18.94833 1.000 53.04214  ? 268 LEU A HA   1 
ATOM   4030 H HB2  . LEU A 1 268 ? -30.62450 -19.07134 -17.75719 1.000 50.82000  ? 268 LEU A HB2  1 
ATOM   4031 H HB3  . LEU A 1 268 ? -30.75962 -19.94612 -16.43737 1.000 50.82000  ? 268 LEU A HB3  1 
ATOM   4032 H HG   . LEU A 1 268 ? -28.52733 -20.06950 -16.18776 1.000 48.13964  ? 268 LEU A HG   1 
ATOM   4033 H HD11 . LEU A 1 268 ? -27.03616 -19.17543 -17.81152 1.000 46.49168  ? 268 LEU A HD11 1 
ATOM   4034 H HD12 . LEU A 1 268 ? -27.76347 -20.51540 -18.25764 1.000 46.49168  ? 268 LEU A HD12 1 
ATOM   4035 H HD13 . LEU A 1 268 ? -28.26927 -19.11494 -18.81116 1.000 46.49168  ? 268 LEU A HD13 1 
ATOM   4036 H HD21 . LEU A 1 268 ? -29.40935 -17.98332 -15.55115 1.000 52.17230  ? 268 LEU A HD21 1 
ATOM   4037 H HD22 . LEU A 1 268 ? -27.90467 -17.82115 -16.03399 1.000 52.17230  ? 268 LEU A HD22 1 
ATOM   4038 H HD23 . LEU A 1 268 ? -29.09748 -17.41741 -17.00235 1.000 52.17230  ? 268 LEU A HD23 1 
ATOM   4039 N N    . LYS A 1 269 ? -30.62951 -22.86842 -16.46172 1.000 52.49458  ? 269 LYS A N    1 
ATOM   4040 C CA   . LYS A 1 269 ? -30.16139 -24.06875 -15.77706 1.000 46.51463  ? 269 LYS A CA   1 
ATOM   4041 C C    . LYS A 1 269 ? -29.77518 -25.15054 -16.77813 1.000 50.81801  ? 269 LYS A C    1 
ATOM   4042 O O    . LYS A 1 269 ? -28.69346 -25.74181 -16.68847 1.000 58.45312  ? 269 LYS A O    1 
ATOM   4043 C CB   . LYS A 1 269 ? -31.24033 -24.58041 -14.82121 1.000 44.02608  ? 269 LYS A CB   1 
ATOM   4044 H H    . LYS A 1 269 ? -31.39286 -22.57785 -16.19253 1.000 62.98726  ? 269 LYS A H    1 
ATOM   4045 H HA   . LYS A 1 269 ? -29.37674 -23.84586 -15.25215 1.000 55.81133  ? 269 LYS A HA   1 
ATOM   4046 N N    . GLU A 1 270 ? -30.64805 -25.41385 -17.75341 1.000 55.39550  ? 270 GLU A N    1 
ATOM   4047 C CA   . GLU A 1 270 ? -30.34961 -26.44595 -18.73942 1.000 60.29816  ? 270 GLU A CA   1 
ATOM   4048 C C    . GLU A 1 270 ? -29.18480 -26.04520 -19.63446 1.000 55.31164  ? 270 GLU A C    1 
ATOM   4049 O O    . GLU A 1 270 ? -28.46846 -26.91672 -20.13968 1.000 60.42082  ? 270 GLU A O    1 
ATOM   4050 C CB   . GLU A 1 270 ? -31.58571 -26.74840 -19.58888 1.000 50.17750  ? 270 GLU A CB   1 
ATOM   4051 C CG   . GLU A 1 270 ? -32.76358 -27.31846 -18.80742 1.000 66.63397  ? 270 GLU A CG   1 
ATOM   4052 C CD   . GLU A 1 270 ? -32.37147 -28.45455 -17.87549 1.000 72.79537  ? 270 GLU A CD   1 
ATOM   4053 O OE1  . GLU A 1 270 ? -31.50439 -29.27343 -18.25361 1.000 74.86909  ? 270 GLU A OE1  1 
ATOM   4054 O OE2  . GLU A 1 270 ? -32.92671 -28.51872 -16.75706 1.000 75.68800  ? 270 GLU A OE2  1 
ATOM   4055 H H    . GLU A 1 270 ? -31.40307 -25.01674 -17.86225 1.000 66.46837  ? 270 GLU A H    1 
ATOM   4056 H HA   . GLU A 1 270 ? -30.10652 -27.25843 -18.26859 1.000 72.35156  ? 270 GLU A HA   1 
ATOM   4057 H HB2  . GLU A 1 270 ? -31.88231 -25.92508 -20.00730 1.000 60.20678  ? 270 GLU A HB2  1 
ATOM   4058 H HB3  . GLU A 1 270 ? -31.34295 -27.39699 -20.26807 1.000 60.20678  ? 270 GLU A HB3  1 
ATOM   4059 H HG2  . GLU A 1 270 ? -33.15451 -26.61275 -18.26886 1.000 79.95453  ? 270 GLU A HG2  1 
ATOM   4060 H HG3  . GLU A 1 270 ? -33.42051 -27.66026 -19.43392 1.000 79.95453  ? 270 GLU A HG3  1 
ATOM   4061 N N    . LEU A 1 271 ? -28.98126 -24.74179 -19.84547 1.000 54.56358  ? 271 LEU A N    1 
ATOM   4062 C CA   . LEU A 1 271 ? -27.85560 -24.29639 -20.66032 1.000 46.93358  ? 271 LEU A CA   1 
ATOM   4063 C C    . LEU A 1 271 ? -26.53028 -24.57567 -19.96345 1.000 52.84310  ? 271 LEU A C    1 
ATOM   4064 O O    . LEU A 1 271 ? -25.55093 -24.96248 -20.61147 1.000 58.17182  ? 271 LEU A O    1 
ATOM   4065 C CB   . LEU A 1 271 ? -27.99195 -22.80733 -20.98002 1.000 51.94613  ? 271 LEU A CB   1 
ATOM   4066 C CG   . LEU A 1 271 ? -28.82806 -22.44844 -22.21176 1.000 42.73801  ? 271 LEU A CG   1 
ATOM   4067 C CD1  . LEU A 1 271 ? -29.15444 -20.96442 -22.22693 1.000 40.20824  ? 271 LEU A CD1  1 
ATOM   4068 C CD2  . LEU A 1 271 ? -28.10184 -22.82982 -23.48715 1.000 47.39498  ? 271 LEU A CD2  1 
ATOM   4069 H H    . LEU A 1 271 ? -29.47228 -24.10859 -19.53311 1.000 65.47007  ? 271 LEU A H    1 
ATOM   4070 H HA   . LEU A 1 271 ? -27.86491 -24.78299 -21.49939 1.000 56.31407  ? 271 LEU A HA   1 
ATOM   4071 H HB2  . LEU A 1 271 ? -28.40565 -22.37279 -20.21783 1.000 62.32913  ? 271 LEU A HB2  1 
ATOM   4072 H HB3  . LEU A 1 271 ? -27.10256 -22.44808 -21.12431 1.000 62.32913  ? 271 LEU A HB3  1 
ATOM   4073 H HG   . LEU A 1 271 ? -29.65962 -22.94630 -22.17250 1.000 51.27938  ? 271 LEU A HG   1 
ATOM   4074 H HD11 . LEU A 1 271 ? -28.33441 -20.45952 -22.11062 1.000 48.24365  ? 271 LEU A HD11 1 
ATOM   4075 H HD12 . LEU A 1 271 ? -29.56345 -20.73970 -23.07729 1.000 48.24365  ? 271 LEU A HD12 1 
ATOM   4076 H HD13 . LEU A 1 271 ? -29.76894 -20.76879 -21.50235 1.000 48.24365  ? 271 LEU A HD13 1 
ATOM   4077 H HD21 . LEU A 1 271 ? -28.73893 -22.85387 -24.21820 1.000 56.86775  ? 271 LEU A HD21 1 
ATOM   4078 H HD22 . LEU A 1 271 ? -27.41472 -22.16969 -23.66877 1.000 56.86775  ? 271 LEU A HD22 1 
ATOM   4079 H HD23 . LEU A 1 271 ? -27.69815 -23.70419 -23.37130 1.000 56.86775  ? 271 LEU A HD23 1 
ATOM   4080 N N    . LEU A 1 272 ? -26.47737 -24.38869 -18.64368 1.000 49.49810  ? 272 LEU A N    1 
ATOM   4081 C CA   . LEU A 1 272 ? -25.26031 -24.70831 -17.91085 1.000 54.63593  ? 272 LEU A CA   1 
ATOM   4082 C C    . LEU A 1 272 ? -25.06783 -26.21133 -17.75245 1.000 58.37207  ? 272 LEU A C    1 
ATOM   4083 O O    . LEU A 1 272 ? -23.93243 -26.66304 -17.59075 1.000 63.55709  ? 272 LEU A O    1 
ATOM   4084 C CB   . LEU A 1 272 ? -25.27661 -24.04250 -16.53437 1.000 54.92285  ? 272 LEU A CB   1 
ATOM   4085 C CG   . LEU A 1 272 ? -25.64649 -22.55712 -16.49640 1.000 51.38864  ? 272 LEU A CG   1 
ATOM   4086 C CD1  . LEU A 1 272 ? -25.16422 -21.92035 -15.20418 1.000 48.54481  ? 272 LEU A CD1  1 
ATOM   4087 C CD2  . LEU A 1 272 ? -25.08872 -21.81282 -17.69702 1.000 52.15967  ? 272 LEU A CD2  1 
ATOM   4088 H H    . LEU A 1 272 ? -27.12107 -24.08399 -18.16159 1.000 59.39149  ? 272 LEU A H    1 
ATOM   4089 H HA   . LEU A 1 272 ? -24.50220 -24.35409 -18.40147 1.000 65.55688  ? 272 LEU A HA   1 
ATOM   4090 H HB2  . LEU A 1 272 ? -25.92196 -24.51084 -15.98203 1.000 65.90119  ? 272 LEU A HB2  1 
ATOM   4091 H HB3  . LEU A 1 272 ? -24.38960 -24.12496 -16.15054 1.000 65.90119  ? 272 LEU A HB3  1 
ATOM   4092 H HG   . LEU A 1 272 ? -26.61300 -22.48352 -16.53285 1.000 61.66014  ? 272 LEU A HG   1 
ATOM   4093 H HD11 . LEU A 1 272 ? -25.39254 -22.50108 -14.46154 1.000 58.24755  ? 272 LEU A HD11 1 
ATOM   4094 H HD12 . LEU A 1 272 ? -24.20231 -21.80379 -15.24934 1.000 58.24755  ? 272 LEU A HD12 1 
ATOM   4095 H HD13 . LEU A 1 272 ? -25.59706 -21.05907 -15.09579 1.000 58.24755  ? 272 LEU A HD13 1 
ATOM   4096 H HD21 . LEU A 1 272 ? -25.06329 -20.86411 -17.49655 1.000 62.58537  ? 272 LEU A HD21 1 
ATOM   4097 H HD22 . LEU A 1 272 ? -24.19286 -22.13620 -17.88078 1.000 62.58537  ? 272 LEU A HD22 1 
ATOM   4098 H HD23 . LEU A 1 272 ? -25.66205 -21.97387 -18.46269 1.000 62.58537  ? 272 LEU A HD23 1 
ATOM   4099 N N    . GLN A 1 273 ? -26.15098 -26.99031 -17.80668 1.000 63.73903  ? 273 GLN A N    1 
ATOM   4100 C CA   . GLN A 1 273 ? -26.05701 -28.43683 -17.63337 1.000 63.92122  ? 273 GLN A CA   1 
ATOM   4101 C C    . GLN A 1 273 ? -25.71986 -29.15225 -18.93784 1.000 57.84404  ? 273 GLN A C    1 
ATOM   4102 O O    . GLN A 1 273 ? -24.86131 -30.04001 -18.94988 1.000 56.62548  ? 273 GLN A O    1 
ATOM   4103 C CB   . GLN A 1 273 ? -27.36963 -28.97679 -17.05744 1.000 67.53927  ? 273 GLN A CB   1 
ATOM   4104 C CG   . GLN A 1 273 ? -27.46174 -28.89573 -15.53298 1.000 64.00683  ? 273 GLN A CG   1 
ATOM   4105 C CD   . GLN A 1 273 ? -28.87381 -29.11100 -15.00729 1.000 67.93698  ? 273 GLN A CD   1 
ATOM   4106 O OE1  . GLN A 1 273 ? -29.73306 -29.66129 -15.69741 1.000 69.12006  ? 273 GLN A OE1  1 
ATOM   4107 N NE2  . GLN A 1 273 ? -29.11915 -28.66768 -13.77948 1.000 63.36328  ? 273 GLN A NE2  1 
ATOM   4108 H H    . GLN A 1 273 ? -26.95068 -26.70464 -17.94258 1.000 76.48060  ? 273 GLN A H    1 
ATOM   4109 H HA   . GLN A 1 273 ? -25.34371 -28.62442 -17.00335 1.000 76.69923  ? 273 GLN A HA   1 
ATOM   4110 H HB2  . GLN A 1 273 ? -28.10509 -28.46214 -17.42504 1.000 81.04090  ? 273 GLN A HB2  1 
ATOM   4111 H HB3  . GLN A 1 273 ? -27.45887 -29.90933 -17.30904 1.000 81.04090  ? 273 GLN A HB3  1 
ATOM   4112 H HG2  . GLN A 1 273 ? -26.89205 -29.57910 -15.14650 1.000 76.80197  ? 273 GLN A HG2  1 
ATOM   4113 H HG3  . GLN A 1 273 ? -27.16727 -28.01713 -15.24619 1.000 76.80197  ? 273 GLN A HG3  1 
ATOM   4114 H HE21 . GLN A 1 273 ? -28.49573 -28.28366 -13.32839 1.000 76.02971  ? 273 GLN A HE21 1 
ATOM   4115 H HE22 . GLN A 1 273 ? -29.90141 -28.76466 -13.43560 1.000 76.02971  ? 273 GLN A HE22 1 
ATOM   4116 N N    . ASN A 1 274 ? -26.36489 -28.78361 -20.04239 1.000 60.15213  ? 274 ASN A N    1 
ATOM   4117 C CA   . ASN A 1 274 ? -26.19408 -29.49217 -21.30277 1.000 64.18431  ? 274 ASN A CA   1 
ATOM   4118 C C    . ASN A 1 274 ? -25.31258 -28.73627 -22.29055 1.000 64.24372  ? 274 ASN A C    1 
ATOM   4119 O O    . ASN A 1 274 ? -25.17803 -29.16669 -23.43986 1.000 59.24145  ? 274 ASN A O    1 
ATOM   4120 C CB   . ASN A 1 274 ? -27.56079 -29.77491 -21.93342 1.000 62.67648  ? 274 ASN A CB   1 
ATOM   4121 C CG   . ASN A 1 274 ? -28.62709 -30.10557 -20.89964 1.000 72.60598  ? 274 ASN A CG   1 
ATOM   4122 O OD1  . ASN A 1 274 ? -29.77253 -29.66659 -21.01504 1.000 67.43400  ? 274 ASN A OD1  1 
ATOM   4123 N ND2  . ASN A 1 274 ? -28.25318 -30.87519 -19.88014 1.000 70.47257  ? 274 ASN A ND2  1 
ATOM   4124 H H    . ASN A 1 274 ? -26.91076 -28.12039 -20.08435 1.000 72.17633  ? 274 ASN A H    1 
ATOM   4125 H HA   . ASN A 1 274 ? -25.76541 -30.34283 -21.11967 1.000 77.01494  ? 274 ASN A HA   1 
ATOM   4126 H HB2  . ASN A 1 274 ? -27.85131 -28.99012 -22.42394 1.000 75.20554  ? 274 ASN A HB2  1 
ATOM   4127 H HB3  . ASN A 1 274 ? -27.48112 -30.53155 -22.53513 1.000 75.20554  ? 274 ASN A HB3  1 
ATOM   4128 H HD21 . ASN A 1 274 ? -28.82180 -31.08846 -19.27121 1.000 84.56085  ? 274 ASN A HD21 1 
ATOM   4129 H HD22 . ASN A 1 274 ? -27.44297 -31.15921 -19.83032 1.000 84.56085  ? 274 ASN A HD22 1 
ATOM   4130 N N    . GLY A 1 275 ? -24.70517 -27.62949 -21.87076 1.000 63.97507  ? 275 GLY A N    1 
ATOM   4131 C CA   . GLY A 1 275 ? -23.91799 -26.81804 -22.77721 1.000 49.30545  ? 275 GLY A CA   1 
ATOM   4132 C C    . GLY A 1 275 ? -24.75531 -26.25392 -23.90551 1.000 59.75854  ? 275 GLY A C    1 
ATOM   4133 O O    . GLY A 1 275 ? -25.95923 -26.51749 -23.98158 1.000 50.44890  ? 275 GLY A O    1 
ATOM   4134 H H    . GLY A 1 275 ? -24.73666 -27.33135 -21.06471 1.000 76.76386  ? 275 GLY A H    1 
ATOM   4135 H HA2  . GLY A 1 275 ? -23.52298 -26.07928 -22.28825 1.000 59.16031  ? 275 GLY A HA2  1 
ATOM   4136 H HA3  . GLY A 1 275 ? -23.20917 -27.35803 -23.16047 1.000 59.16031  ? 275 GLY A HA3  1 
ATOM   4137 N N    . MET A 1 276 ? -24.13288 -25.47725 -24.79181 1.000 58.07864  ? 276 MET A N    1 
ATOM   4138 C CA   . MET A 1 276 ? -24.83526 -24.88639 -25.92236 1.000 57.67757  ? 276 MET A CA   1 
ATOM   4139 C C    . MET A 1 276 ? -24.69515 -25.69595 -27.20603 1.000 55.35337  ? 276 MET A C    1 
ATOM   4140 O O    . MET A 1 276 ? -25.35546 -25.36700 -28.19589 1.000 52.53087  ? 276 MET A O    1 
ATOM   4141 C CB   . MET A 1 276 ? -24.34251 -23.45077 -26.15579 1.000 62.42451  ? 276 MET A CB   1 
ATOM   4142 C CG   . MET A 1 276 ? -24.90392 -22.44772 -25.14927 1.000 46.24865  ? 276 MET A CG   1 
ATOM   4143 S SD   . MET A 1 276 ? -24.33504 -20.75647 -25.41020 1.000 69.65961  ? 276 MET A SD   1 
ATOM   4144 C CE   . MET A 1 276 ? -24.91037 -20.45423 -27.07724 1.000 58.87891  ? 276 MET A CE   1 
ATOM   4145 H H    . MET A 1 276 ? -23.29702 -25.27799 -24.75683 1.000 69.68814  ? 276 MET A H    1 
ATOM   4146 H HA   . MET A 1 276 ? -25.77932 -24.83519 -25.70548 1.000 69.20685  ? 276 MET A HA   1 
ATOM   4147 H HB2  . MET A 1 276 ? -23.37530 -23.43566 -26.08379 1.000 74.90318  ? 276 MET A HB2  1 
ATOM   4148 H HB3  . MET A 1 276 ? -24.61364 -23.16654 -27.04270 1.000 74.90318  ? 276 MET A HB3  1 
ATOM   4149 H HG2  . MET A 1 276 ? -25.87162 -22.44737 -25.21604 1.000 55.49215  ? 276 MET A HG2  1 
ATOM   4150 H HG3  . MET A 1 276 ? -24.63301 -22.71610 -24.25737 1.000 55.49215  ? 276 MET A HG3  1 
ATOM   4151 H HE1  . MET A 1 276 ? -24.18070 -20.61195 -27.69661 1.000 70.64846  ? 276 MET A HE1  1 
ATOM   4152 H HE2  . MET A 1 276 ? -25.64538 -21.05658 -27.27173 1.000 70.64846  ? 276 MET A HE2  1 
ATOM   4153 H HE3  . MET A 1 276 ? -25.20965 -19.53413 -27.14609 1.000 70.64846  ? 276 MET A HE3  1 
ATOM   4154 N N    . ASN A 1 277 ? -23.86269 -26.73988 -27.21361 1.000 59.15773  ? 277 ASN A N    1 
ATOM   4155 C CA   . ASN A 1 277 ? -23.77395 -27.67680 -28.33734 1.000 62.46552  ? 277 ASN A CA   1 
ATOM   4156 C C    . ASN A 1 277 ? -23.41218 -26.97138 -29.64204 1.000 55.52358  ? 277 ASN A C    1 
ATOM   4157 O O    . ASN A 1 277 ? -23.93495 -27.29824 -30.70895 1.000 61.02677  ? 277 ASN A O    1 
ATOM   4158 C CB   . ASN A 1 277 ? -25.07947 -28.45869 -28.50653 1.000 59.03167  ? 277 ASN A CB   1 
ATOM   4159 C CG   . ASN A 1 277 ? -25.27062 -29.51589 -27.44095 1.000 64.22909  ? 277 ASN A CG   1 
ATOM   4160 O OD1  . ASN A 1 277 ? -24.85005 -29.34765 -26.29618 1.000 72.10718  ? 277 ASN A OD1  1 
ATOM   4161 N ND2  . ASN A 1 277 ? -25.90536 -30.61918 -27.81481 1.000 61.55340  ? 277 ASN A ND2  1 
ATOM   4162 H H    . ASN A 1 277 ? -23.32859 -26.93076 -26.56715 1.000 70.98305  ? 277 ASN A H    1 
ATOM   4163 H HA   . ASN A 1 277 ? -23.05988 -28.30295 -28.14003 1.000 74.95240  ? 277 ASN A HA   1 
ATOM   4164 H HB2  . ASN A 1 277 ? -25.82634 -27.84194 -28.45459 1.000 70.83178  ? 277 ASN A HB2  1 
ATOM   4165 H HB3  . ASN A 1 277 ? -25.07362 -28.90068 -29.36997 1.000 70.83178  ? 277 ASN A HB3  1 
ATOM   4166 H HD21 . ASN A 1 277 ? -26.03994 -31.25112 -27.24723 1.000 73.85786  ? 277 ASN A HD21 1 
ATOM   4167 H HD22 . ASN A 1 277 ? -26.18226 -30.70247 -28.62474 1.000 73.85786  ? 277 ASN A HD22 1 
ATOM   4168 N N    . GLY A 1 278 ? -22.50819 -25.99860 -29.56252 1.000 48.67489  ? 278 GLY A N    1 
ATOM   4169 C CA   . GLY A 1 278 ? -22.08572 -25.26628 -30.73753 1.000 62.90138  ? 278 GLY A CA   1 
ATOM   4170 C C    . GLY A 1 278 ? -23.09761 -24.28575 -31.28575 1.000 56.81604  ? 278 GLY A C    1 
ATOM   4171 O O    . GLY A 1 278 ? -22.77551 -23.55408 -32.22984 1.000 56.74385  ? 278 GLY A O    1 
ATOM   4172 H H    . GLY A 1 278 ? -22.12675 -25.74741 -28.83382 1.000 58.40364  ? 278 GLY A H    1 
ATOM   4173 H HA2  . GLY A 1 278 ? -21.28241 -24.76848 -30.51890 1.000 75.47543  ? 278 GLY A HA2  1 
ATOM   4174 H HA3  . GLY A 1 278 ? -21.88151 -25.90225 -31.44092 1.000 75.47543  ? 278 GLY A HA3  1 
ATOM   4175 N N    . ARG A 1 279 ? -24.30471 -24.24091 -30.73019 1.000 52.84804  ? 279 ARG A N    1 
ATOM   4176 C CA   . ARG A 1 279 ? -25.30762 -23.28473 -31.16832 1.000 54.54728  ? 279 ARG A CA   1 
ATOM   4177 C C    . ARG A 1 279 ? -24.97619 -21.90129 -30.61487 1.000 51.41713  ? 279 ARG A C    1 
ATOM   4178 O O    . ARG A 1 279 ? -24.15941 -21.75165 -29.70241 1.000 56.17641  ? 279 ARG A O    1 
ATOM   4179 C CB   . ARG A 1 279 ? -26.70046 -23.72796 -30.71639 1.000 58.76868  ? 279 ARG A CB   1 
ATOM   4180 C CG   . ARG A 1 279 ? -26.94011 -25.23405 -30.82058 1.000 54.64332  ? 279 ARG A CG   1 
ATOM   4181 C CD   . ARG A 1 279 ? -28.38709 -25.59891 -30.52497 1.000 64.13528  ? 279 ARG A CD   1 
ATOM   4182 N NE   . ARG A 1 279 ? -29.13628 -25.84020 -31.75250 1.000 72.34242  ? 279 ARG A NE   1 
ATOM   4183 C CZ   . ARG A 1 279 ? -29.31938 -27.03484 -32.30107 1.000 79.95736  ? 279 ARG A CZ   1 
ATOM   4184 N NH1  . ARG A 1 279 ? -28.86606 -28.13861 -31.72697 1.000 81.95667  ? 279 ARG A NH1  1 
ATOM   4185 N NH2  . ARG A 1 279 ? -29.97520 -27.12449 -33.45494 1.000 74.35093  ? 279 ARG A NH2  1 
ATOM   4186 H H    . ARG A 1 279 ? -24.56661 -24.75743 -30.09441 1.000 63.41142  ? 279 ARG A H    1 
ATOM   4187 H HA   . ARG A 1 279 ? -25.31926 -23.23058 -32.13674 1.000 65.45051  ? 279 ARG A HA   1 
ATOM   4188 H HB2  . ARG A 1 279 ? -26.82125 -23.47380 -29.78811 1.000 70.51619  ? 279 ARG A HB2  1 
ATOM   4189 H HB3  . ARG A 1 279 ? -27.36222 -23.28518 -31.27040 1.000 70.51619  ? 279 ARG A HB3  1 
ATOM   4190 H HG2  . ARG A 1 279 ? -26.73034 -25.52994 -31.72021 1.000 65.56575  ? 279 ARG A HG2  1 
ATOM   4191 H HG3  . ARG A 1 279 ? -26.37455 -25.69310 -30.18002 1.000 65.56575  ? 279 ARG A HG3  1 
ATOM   4192 H HD2  . ARG A 1 279 ? -28.41181 -26.40649 -29.98822 1.000 76.95610  ? 279 ARG A HD2  1 
ATOM   4193 H HD3  . ARG A 1 279 ? -28.81128 -24.86947 -30.04654 1.000 76.95610  ? 279 ARG A HD3  1 
ATOM   4194 H HE   . ARG A 1 279 ? -29.48390 -25.16073 -32.14885 1.000 86.80467  ? 279 ARG A HE   1 
ATOM   4195 H HH11 . ARG A 1 279 ? -28.44142 -28.09185 -30.98058 1.000 98.34178  ? 279 ARG A HH11 1 
ATOM   4196 H HH12 . ARG A 1 279 ? -28.99627 -28.90223 -32.10050 1.000 98.34178  ? 279 ARG A HH12 1 
ATOM   4197 H HH21 . ARG A 1 279 ? -30.27438 -26.41385 -33.83583 1.000 89.21489  ? 279 ARG A HH21 1 
ATOM   4198 H HH22 . ARG A 1 279 ? -30.10001 -27.89309 -33.82001 1.000 89.21489  ? 279 ARG A HH22 1 
ATOM   4199 N N    . THR A 1 280 ? -25.61585 -20.88015 -31.18109 1.000 49.01493  ? 280 THR A N    1 
ATOM   4200 C CA   . THR A 1 280 ? -25.36354 -19.50516 -30.77995 1.000 46.90169  ? 280 THR A CA   1 
ATOM   4201 C C    . THR A 1 280 ? -26.65019 -18.82003 -30.33478 1.000 51.29722  ? 280 THR A C    1 
ATOM   4202 O O    . THR A 1 280 ? -27.76190 -19.24487 -30.66584 1.000 44.65584  ? 280 THR A O    1 
ATOM   4203 C CB   . THR A 1 280 ? -24.72335 -18.69301 -31.91616 1.000 42.26232  ? 280 THR A CB   1 
ATOM   4204 O OG1  . THR A 1 280 ? -25.56627 -18.72874 -33.07466 1.000 53.63412  ? 280 THR A OG1  1 
ATOM   4205 C CG2  . THR A 1 280 ? -23.35206 -19.24585 -32.26502 1.000 36.53969  ? 280 THR A CG2  1 
ATOM   4206 H H    . THR A 1 280 ? -26.20356 -20.96299 -31.80346 1.000 58.81168  ? 280 THR A H    1 
ATOM   4207 H HA   . THR A 1 280 ? -24.75534 -19.51800 -30.02442 1.000 56.27580  ? 280 THR A HA   1 
ATOM   4208 H HB   . THR A 1 280 ? -24.61434 -17.77254 -31.63024 1.000 50.70855  ? 280 THR A HB   1 
ATOM   4209 H HG1  . THR A 1 280 ? -26.27527 -18.30303 -32.92733 1.000 64.35471  ? 280 THR A HG1  1 
ATOM   4210 H HG21 . THR A 1 280 ? -23.39008 -20.21317 -32.32621 1.000 43.84139  ? 280 THR A HG21 1 
ATOM   4211 H HG22 . THR A 1 280 ? -23.05693 -18.88790 -33.11688 1.000 43.84139  ? 280 THR A HG22 1 
ATOM   4212 H HG23 . THR A 1 280 ? -22.71075 -18.99869 -31.58053 1.000 43.84139  ? 280 THR A HG23 1 
ATOM   4213 N N    . ILE A 1 281 ? -26.47030 -17.74820 -29.56445 1.000 40.81937  ? 281 ILE A N    1 
ATOM   4214 C CA   . ILE A 1 281 ? -27.55254 -16.88828 -29.09960 1.000 39.07279  ? 281 ILE A CA   1 
ATOM   4215 C C    . ILE A 1 281 ? -27.14336 -15.45513 -29.40617 1.000 41.51129  ? 281 ILE A C    1 
ATOM   4216 O O    . ILE A 1 281 ? -26.11405 -14.98145 -28.90876 1.000 38.56898  ? 281 ILE A O    1 
ATOM   4217 C CB   . ILE A 1 281 ? -27.83465 -17.06560 -27.59708 1.000 37.91521  ? 281 ILE A CB   1 
ATOM   4218 C CG1  . ILE A 1 281 ? -28.26747 -18.50581 -27.30509 1.000 38.14295  ? 281 ILE A CG1  1 
ATOM   4219 C CG2  . ILE A 1 281 ? -28.89494 -16.06508 -27.12641 1.000 40.50543  ? 281 ILE A CG2  1 
ATOM   4220 C CD1  . ILE A 1 281 ? -28.54882 -18.78417 -25.83903 1.000 40.73354  ? 281 ILE A CD1  1 
ATOM   4221 H H    . ILE A 1 281 ? -25.69796 -17.49009 -29.28791 1.000 48.97702  ? 281 ILE A H    1 
ATOM   4222 H HA   . ILE A 1 281 ? -28.36895 -17.09504 -29.58088 1.000 46.88112  ? 281 ILE A HA   1 
ATOM   4223 H HB   . ILE A 1 281 ? -27.01685 -16.88888 -27.10628 1.000 45.49203  ? 281 ILE A HB   1 
ATOM   4224 H HG12 . ILE A 1 281 ? -29.07964 -18.69259 -27.80146 1.000 45.76532  ? 281 ILE A HG12 1 
ATOM   4225 H HG13 . ILE A 1 281 ? -27.56009 -19.10605 -27.58834 1.000 45.76532  ? 281 ILE A HG13 1 
ATOM   4226 H HG21 . ILE A 1 281 ? -28.54456 -15.16557 -27.22137 1.000 48.60028  ? 281 ILE A HG21 1 
ATOM   4227 H HG22 . ILE A 1 281 ? -29.69104 -16.16915 -27.67074 1.000 48.60028  ? 281 ILE A HG22 1 
ATOM   4228 H HG23 . ILE A 1 281 ? -29.10494 -16.24177 -26.19605 1.000 48.60028  ? 281 ILE A HG23 1 
ATOM   4229 H HD11 . ILE A 1 281 ? -28.64884 -19.74070 -25.71274 1.000 48.87403  ? 281 ILE A HD11 1 
ATOM   4230 H HD12 . ILE A 1 281 ? -27.80689 -18.45610 -25.30724 1.000 48.87403  ? 281 ILE A HD12 1 
ATOM   4231 H HD13 . ILE A 1 281 ? -29.36628 -18.32938 -25.58245 1.000 48.87403  ? 281 ILE A HD13 1 
ATOM   4232 N N    . LEU A 1 282 ? -27.94427 -14.76798 -30.21905 1.000 38.97754  ? 282 LEU A N    1 
ATOM   4233 C CA   . LEU A 1 282 ? -27.59745 -13.43597 -30.71350 1.000 36.97714  ? 282 LEU A CA   1 
ATOM   4234 C C    . LEU A 1 282 ? -26.17177 -13.40576 -31.26163 1.000 38.50167  ? 282 LEU A C    1 
ATOM   4235 O O    . LEU A 1 282 ? -25.44098 -12.42533 -31.10407 1.000 39.43622  ? 282 LEU A O    1 
ATOM   4236 C CB   . LEU A 1 282 ? -27.77553 -12.38034 -29.62359 1.000 37.90309  ? 282 LEU A CB   1 
ATOM   4237 C CG   . LEU A 1 282 ? -29.20522 -12.04646 -29.19774 1.000 38.86532  ? 282 LEU A CG   1 
ATOM   4238 C CD1  . LEU A 1 282 ? -29.17321 -11.11927 -27.99407 1.000 43.76555  ? 282 LEU A CD1  1 
ATOM   4239 C CD2  . LEU A 1 282 ? -30.00015 -11.42136 -30.33462 1.000 36.41125  ? 282 LEU A CD2  1 
ATOM   4240 H H    . LEU A 1 282 ? -28.70383 -15.05505 -30.50235 1.000 46.76682  ? 282 LEU A H    1 
ATOM   4241 H HA   . LEU A 1 282 ? -28.19951 -13.22031 -31.44282 1.000 44.36634  ? 282 LEU A HA   1 
ATOM   4242 H HB2  . LEU A 1 282 ? -27.31070 -12.69037 -28.83067 1.000 45.47747  ? 282 LEU A HB2  1 
ATOM   4243 H HB3  . LEU A 1 282 ? -27.37628 -11.55521 -29.94086 1.000 45.47747  ? 282 LEU A HB3  1 
ATOM   4244 H HG   . LEU A 1 282 ? -29.66033 -12.86793 -28.95493 1.000 46.63215  ? 282 LEU A HG   1 
ATOM   4245 H HD11 . LEU A 1 282 ? -28.69644 -10.30883 -28.23232 1.000 52.51243  ? 282 LEU A HD11 1 
ATOM   4246 H HD12 . LEU A 1 282 ? -30.08341 -10.90411 -27.73689 1.000 52.51243  ? 282 LEU A HD12 1 
ATOM   4247 H HD13 . LEU A 1 282 ? -28.71983 -11.56686 -27.26263 1.000 52.51243  ? 282 LEU A HD13 1 
ATOM   4248 H HD21 . LEU A 1 282 ? -29.53231 -10.63262 -30.65072 1.000 43.68727  ? 282 LEU A HD21 1 
ATOM   4249 H HD22 . LEU A 1 282 ? -30.08365 -12.06686 -31.05382 1.000 43.68727  ? 282 LEU A HD22 1 
ATOM   4250 H HD23 . LEU A 1 282 ? -30.87945 -11.17537 -30.00719 1.000 43.68727  ? 282 LEU A HD23 1 
ATOM   4251 N N    . GLY A 1 283 ? -25.76721 -14.50023 -31.90472 1.000 39.55060  ? 283 GLY A N    1 
ATOM   4252 C CA   . GLY A 1 283 ? -24.48537 -14.58234 -32.56245 1.000 38.88181  ? 283 GLY A CA   1 
ATOM   4253 C C    . GLY A 1 283 ? -23.35047 -15.11151 -31.71174 1.000 38.21226  ? 283 GLY A C    1 
ATOM   4254 O O    . GLY A 1 283 ? -22.31310 -15.49416 -32.26321 1.000 47.49894  ? 283 GLY A O    1 
ATOM   4255 H H    . GLY A 1 283 ? -26.23480 -15.21905 -31.96996 1.000 47.45449  ? 283 GLY A H    1 
ATOM   4256 H HA2  . GLY A 1 283 ? -24.57096 -15.16551 -33.33284 1.000 46.65194  ? 283 GLY A HA2  1 
ATOM   4257 H HA3  . GLY A 1 283 ? -24.23638 -13.69478 -32.86436 1.000 46.65194  ? 283 GLY A HA3  1 
ATOM   4258 N N    . SER A 1 284 ? -23.51057 -15.15347 -30.39264 1.000 40.95997  ? 284 SER A N    1 
ATOM   4259 C CA   . SER A 1 284 ? -22.43343 -15.56901 -29.50510 1.000 40.91145  ? 284 SER A CA   1 
ATOM   4260 C C    . SER A 1 284 ? -22.52987 -17.05448 -29.18228 1.000 42.99579  ? 284 SER A C    1 
ATOM   4261 O O    . SER A 1 284 ? -23.62073 -17.58902 -28.96502 1.000 42.99544  ? 284 SER A O    1 
ATOM   4262 C CB   . SER A 1 284 ? -22.46473 -14.75947 -28.20752 1.000 37.04128  ? 284 SER A CB   1 
ATOM   4263 O OG   . SER A 1 284 ? -21.44554 -15.18709 -27.31931 1.000 50.25295  ? 284 SER A OG   1 
ATOM   4264 H H    . SER A 1 284 ? -24.23906 -14.94439 -29.98622 1.000 49.14574  ? 284 SER A H    1 
ATOM   4265 H HA   . SER A 1 284 ? -21.58590 -15.41437 -29.95082 1.000 49.08751  ? 284 SER A HA   1 
ATOM   4266 H HB2  . SER A 1 284 ? -22.32783 -13.82230 -28.41701 1.000 44.44331  ? 284 SER A HB2  1 
ATOM   4267 H HB3  . SER A 1 284 ? -23.32703 -14.88140 -27.78036 1.000 44.44331  ? 284 SER A HB3  1 
ATOM   4268 H HG   . SER A 1 284 ? -20.69786 -15.14895 -27.70025 1.000 60.29731  ? 284 SER A HG   1 
ATOM   4269 N N    . ALA A 1 285 ? -21.37581 -17.71576 -29.14890 1.000 51.48130  ? 285 ALA A N    1 
ATOM   4270 C CA   . ALA A 1 285 ? -21.28584 -19.10937 -28.73795 1.000 51.25426  ? 285 ALA A CA   1 
ATOM   4271 C C    . ALA A 1 285 ? -21.07355 -19.26055 -27.23842 1.000 50.93653  ? 285 ALA A C    1 
ATOM   4272 O O    . ALA A 1 285 ? -21.04601 -20.39165 -26.74173 1.000 53.32968  ? 285 ALA A O    1 
ATOM   4273 C CB   . ALA A 1 285 ? -20.15344 -19.81085 -29.49432 1.000 53.54713  ? 285 ALA A CB   1 
ATOM   4274 H H    . ALA A 1 285 ? -20.61820 -17.37039 -29.36417 1.000 61.77133  ? 285 ALA A H    1 
ATOM   4275 H HA   . ALA A 1 285 ? -22.11375 -19.55858 -28.96963 1.000 61.49888  ? 285 ALA A HA   1 
ATOM   4276 H HB1  . ALA A 1 285 ? -20.04720 -20.70847 -29.14235 1.000 64.25033  ? 285 ALA A HB1  1 
ATOM   4277 H HB2  . ALA A 1 285 ? -20.37980 -19.84972 -30.43673 1.000 64.25033  ? 285 ALA A HB2  1 
ATOM   4278 H HB3  . ALA A 1 285 ? -19.33295 -19.30820 -29.37167 1.000 64.25033  ? 285 ALA A HB3  1 
ATOM   4279 N N    . LEU A 1 286 ? -20.91905 -18.15376 -26.51480 1.000 42.69041  ? 286 LEU A N    1 
ATOM   4280 C CA   . LEU A 1 286 ? -20.84254 -18.14829 -25.06298 1.000 43.01820  ? 286 LEU A CA   1 
ATOM   4281 C C    . LEU A 1 286 ? -21.93168 -17.23970 -24.50489 1.000 45.78100  ? 286 LEU A C    1 
ATOM   4282 O O    . LEU A 1 286 ? -22.42696 -16.33694 -25.18502 1.000 43.34781  ? 286 LEU A O    1 
ATOM   4283 C CB   . LEU A 1 286 ? -19.46909 -17.67037 -24.57801 1.000 45.99752  ? 286 LEU A CB   1 
ATOM   4284 C CG   . LEU A 1 286 ? -18.25575 -18.30396 -25.25724 1.000 55.47288  ? 286 LEU A CG   1 
ATOM   4285 C CD1  . LEU A 1 286 ? -16.99679 -17.53469 -24.89386 1.000 57.54452  ? 286 LEU A CD1  1 
ATOM   4286 C CD2  . LEU A 1 286 ? -18.12872 -19.76472 -24.86990 1.000 57.39344  ? 286 LEU A CD2  1 
ATOM   4287 H H    . LEU A 1 286 ? -20.85417 -17.36788 -26.85800 1.000 51.22227  ? 286 LEU A H    1 
ATOM   4288 H HA   . LEU A 1 286 ? -20.98324 -19.04678 -24.72563 1.000 51.61561  ? 286 LEU A HA   1 
ATOM   4289 H HB2  . LEU A 1 286 ? -19.41305 -16.71343 -24.72639 1.000 55.19079  ? 286 LEU A HB2  1 
ATOM   4290 H HB3  . LEU A 1 286 ? -19.39994 -17.86371 -23.62999 1.000 55.19079  ? 286 LEU A HB3  1 
ATOM   4291 H HG   . LEU A 1 286 ? -18.36817 -18.26512 -26.21992 1.000 66.56123  ? 286 LEU A HG   1 
ATOM   4292 H HD11 . LEU A 1 286 ? -16.83123 -17.63104 -23.94296 1.000 69.04720  ? 286 LEU A HD11 1 
ATOM   4293 H HD12 . LEU A 1 286 ? -16.25021 -17.89471 -25.39774 1.000 69.04720  ? 286 LEU A HD12 1 
ATOM   4294 H HD13 . LEU A 1 286 ? -17.12396 -16.59867 -25.11429 1.000 69.04720  ? 286 LEU A HD13 1 
ATOM   4295 H HD21 . LEU A 1 286 ? -17.27568 -20.10202 -25.18525 1.000 68.86590  ? 286 LEU A HD21 1 
ATOM   4296 H HD22 . LEU A 1 286 ? -18.17791 -19.84078 -23.90414 1.000 68.86590  ? 286 LEU A HD22 1 
ATOM   4297 H HD23 . LEU A 1 286 ? -18.85322 -20.26389 -25.27834 1.000 68.86590  ? 286 LEU A HD23 1 
ATOM   4298 N N    . LEU A 1 287 ? -22.30448 -17.48302 -23.25311 1.000 43.42277  ? 287 LEU A N    1 
ATOM   4299 C CA   . LEU A 1 287 ? -23.32697 -16.67305 -22.60388 1.000 39.38778  ? 287 LEU A CA   1 
ATOM   4300 C C    . LEU A 1 287 ? -22.71948 -15.33565 -22.19331 1.000 39.51200  ? 287 LEU A C    1 
ATOM   4301 O O    . LEU A 1 287 ? -21.71156 -15.29372 -21.48015 1.000 37.91520  ? 287 LEU A O    1 
ATOM   4302 C CB   . LEU A 1 287 ? -23.91391 -17.41082 -21.40366 1.000 42.16286  ? 287 LEU A CB   1 
ATOM   4303 C CG   . LEU A 1 287 ? -24.57020 -18.75809 -21.73097 1.000 44.54130  ? 287 LEU A CG   1 
ATOM   4304 C CD1  . LEU A 1 287 ? -25.20316 -19.35742 -20.48625 1.000 46.43261  ? 287 LEU A CD1  1 
ATOM   4305 C CD2  . LEU A 1 287 ? -25.60765 -18.62965 -22.84079 1.000 44.19350  ? 287 LEU A CD2  1 
ATOM   4306 H H    . LEU A 1 287 ? -21.98113 -18.10946 -22.76055 1.000 52.10109  ? 287 LEU A H    1 
ATOM   4307 H HA   . LEU A 1 287 ? -24.05276 -16.50112 -23.22402 1.000 47.25911  ? 287 LEU A HA   1 
ATOM   4308 H HB2  . LEU A 1 287 ? -23.20025 -17.58038 -20.76897 1.000 50.58921  ? 287 LEU A HB2  1 
ATOM   4309 H HB3  . LEU A 1 287 ? -24.59128 -16.84702 -20.99843 1.000 50.58921  ? 287 LEU A HB3  1 
ATOM   4310 H HG   . LEU A 1 287 ? -23.87848 -19.35855 -22.05013 1.000 53.44333  ? 287 LEU A HG   1 
ATOM   4311 H HD11 . LEU A 1 287 ? -25.49530 -20.26093 -20.68431 1.000 55.71291  ? 287 LEU A HD11 1 
ATOM   4312 H HD12 . LEU A 1 287 ? -24.54582 -19.37118 -19.77307 1.000 55.71291  ? 287 LEU A HD12 1 
ATOM   4313 H HD13 . LEU A 1 287 ? -25.96297 -18.81382 -20.22534 1.000 55.71291  ? 287 LEU A HD13 1 
ATOM   4314 H HD21 . LEU A 1 287 ? -26.07384 -19.47486 -22.93664 1.000 53.02597  ? 287 LEU A HD21 1 
ATOM   4315 H HD22 . LEU A 1 287 ? -26.23670 -17.92974 -22.60560 1.000 53.02597  ? 287 LEU A HD22 1 
ATOM   4316 H HD23 . LEU A 1 287 ? -25.15707 -18.40455 -23.66977 1.000 53.02597  ? 287 LEU A HD23 1 
ATOM   4317 N N    . GLU A 1 288 ? -23.32990 -14.24989 -22.65819 1.000 44.27885  ? 288 GLU A N    1 
ATOM   4318 C CA   . GLU A 1 288 ? -22.83283 -12.89658 -22.44466 1.000 42.08659  ? 288 GLU A CA   1 
ATOM   4319 C C    . GLU A 1 288 ? -23.36786 -12.34426 -21.12904 1.000 39.75559  ? 288 GLU A C    1 
ATOM   4320 O O    . GLU A 1 288 ? -24.54984 -12.50324 -20.81401 1.000 46.77325  ? 288 GLU A O    1 
ATOM   4321 C CB   . GLU A 1 288 ? -23.26119 -12.01057 -23.61820 1.000 40.80776  ? 288 GLU A CB   1 
ATOM   4322 C CG   . GLU A 1 288 ? -22.80924 -10.56494 -23.55036 1.000 54.62317  ? 288 GLU A CG   1 
ATOM   4323 C CD   . GLU A 1 288 ? -21.32180 -10.40325 -23.76929 1.000 57.16164  ? 288 GLU A CD   1 
ATOM   4324 O OE1  . GLU A 1 288 ? -20.77225 -11.07906 -24.66647 1.000 55.85448  ? 288 GLU A OE1  1 
ATOM   4325 O OE2  . GLU A 1 288 ? -20.70514 -9.60183  -23.03575 1.000 50.55917  ? 288 GLU A OE2  1 
ATOM   4326 H H    . GLU A 1 288 ? -24.05792 -14.27235 -23.11545 1.000 53.12839  ? 288 GLU A H    1 
ATOM   4327 H HA   . GLU A 1 288 ? -21.86436 -12.89194 -22.39029 1.000 50.49769  ? 288 GLU A HA   1 
ATOM   4328 H HB2  . GLU A 1 288 ? -22.89599 -12.38825 -24.43361 1.000 48.96308  ? 288 GLU A HB2  1 
ATOM   4329 H HB3  . GLU A 1 288 ? -24.23033 -12.00744 -23.65905 1.000 48.96308  ? 288 GLU A HB3  1 
ATOM   4330 H HG2  . GLU A 1 288 ? -23.26985 -10.05767 -24.23696 1.000 65.54158  ? 288 GLU A HG2  1 
ATOM   4331 H HG3  . GLU A 1 288 ? -23.02349 -10.20802 -22.67423 1.000 65.54158  ? 288 GLU A HG3  1 
ATOM   4332 N N    . ASP A 1 289 ? -22.49319 -11.68580 -20.35657 1.000 38.27987  ? 289 ASP A N    1 
ATOM   4333 C CA   . ASP A 1 289 ? -22.87366 -11.24319 -19.01895 1.000 41.82298  ? 289 ASP A CA   1 
ATOM   4334 C C    . ASP A 1 289 ? -22.48498 -9.79712  -18.72118 1.000 39.31929  ? 289 ASP A C    1 
ATOM   4335 O O    . ASP A 1 289 ? -22.43948 -9.41135  -17.54788 1.000 39.24704  ? 289 ASP A O    1 
ATOM   4336 C CB   . ASP A 1 289 ? -22.26813 -12.16829 -17.95517 1.000 38.08007  ? 289 ASP A CB   1 
ATOM   4337 C CG   . ASP A 1 289 ? -20.81393 -11.84776 -17.65131 1.000 43.32670  ? 289 ASP A CG   1 
ATOM   4338 O OD1  . ASP A 1 289 ? -20.11210 -11.31030 -18.53612 1.000 38.57275  ? 289 ASP A OD1  1 
ATOM   4339 O OD2  . ASP A 1 289 ? -20.37425 -12.14064 -16.51818 1.000 34.12191  ? 289 ASP A OD2  1 
ATOM   4340 H H    . ASP A 1 289 ? -21.68795 -11.48926 -20.58584 1.000 45.92962  ? 289 ASP A H    1 
ATOM   4341 H HA   . ASP A 1 289 ? -23.84116 -11.28751 -18.96515 1.000 50.18135  ? 289 ASP A HA   1 
ATOM   4342 H HB2  . ASP A 1 289 ? -22.77327 -12.07600 -17.13224 1.000 45.68985  ? 289 ASP A HB2  1 
ATOM   4343 H HB3  . ASP A 1 289 ? -22.31306 -13.08431 -18.27107 1.000 45.68985  ? 289 ASP A HB3  1 
ATOM   4344 N N    . GLU A 1 290 ? -22.22142 -8.97754  -19.74117 1.000 35.34499  ? 290 GLU A N    1 
ATOM   4345 C CA   . GLU A 1 290 ? -21.89779 -7.56970  -19.52983 1.000 39.59342  ? 290 GLU A CA   1 
ATOM   4346 C C    . GLU A 1 290 ? -22.99492 -6.64358  -20.05384 1.000 38.75334  ? 290 GLU A C    1 
ATOM   4347 O O    . GLU A 1 290 ? -22.72023 -5.51833  -20.47761 1.000 35.00294  ? 290 GLU A O    1 
ATOM   4348 C CB   . GLU A 1 290 ? -20.54473 -7.22322  -20.15508 1.000 30.22558  ? 290 GLU A CB   1 
ATOM   4349 C CG   . GLU A 1 290 ? -19.38801 -7.97778  -19.49388 1.000 36.14858  ? 290 GLU A CG   1 
ATOM   4350 C CD   . GLU A 1 290 ? -18.04234 -7.26028  -19.56170 1.000 45.20848  ? 290 GLU A CD   1 
ATOM   4351 O OE1  . GLU A 1 290 ? -17.89951 -6.27843  -20.32284 1.000 48.08184  ? 290 GLU A OE1  1 
ATOM   4352 O OE2  . GLU A 1 290 ? -17.11834 -7.68985  -18.83652 1.000 38.56738  ? 290 GLU A OE2  1 
ATOM   4353 H H    . GLU A 1 290 ? -22.22462 -9.21740  -20.56703 1.000 42.40776  ? 290 GLU A H    1 
ATOM   4354 H HA   . GLU A 1 290 ? -21.82380 -7.41496  -18.57511 1.000 47.50588  ? 290 GLU A HA   1 
ATOM   4355 H HB2  . GLU A 1 290 ? -20.56041 -7.45851  -21.09598 1.000 36.26446  ? 290 GLU A HB2  1 
ATOM   4356 H HB3  . GLU A 1 290 ? -20.38247 -6.27229  -20.05357 1.000 36.26446  ? 290 GLU A HB3  1 
ATOM   4357 H HG2  . GLU A 1 290 ? -19.60125 -8.11134  -18.55708 1.000 43.37207  ? 290 GLU A HG2  1 
ATOM   4358 H HG3  . GLU A 1 290 ? -19.28495 -8.83491  -19.93614 1.000 43.37207  ? 290 GLU A HG3  1 
ATOM   4359 N N    . PHE A 1 291 ? -24.24358 -7.10418  -20.02174 1.000 35.49946  ? 291 PHE A N    1 
ATOM   4360 C CA   . PHE A 1 291 ? -25.41050 -6.25748  -20.23825 1.000 37.50198  ? 291 PHE A CA   1 
ATOM   4361 C C    . PHE A 1 291 ? -26.25951 -6.31059  -18.97694 1.000 32.27155  ? 291 PHE A C    1 
ATOM   4362 O O    . PHE A 1 291 ? -26.71484 -7.38881  -18.58027 1.000 32.73684  ? 291 PHE A O    1 
ATOM   4363 C CB   . PHE A 1 291 ? -26.23557 -6.71576  -21.44416 1.000 36.79993  ? 291 PHE A CB   1 
ATOM   4364 C CG   . PHE A 1 291 ? -25.54506 -6.53958  -22.76711 1.000 40.32923  ? 291 PHE A CG   1 
ATOM   4365 C CD1  . PHE A 1 291 ? -25.51585 -5.30427  -23.39220 1.000 40.82535  ? 291 PHE A CD1  1 
ATOM   4366 C CD2  . PHE A 1 291 ? -24.95234 -7.61772  -23.40019 1.000 36.18836  ? 291 PHE A CD2  1 
ATOM   4367 C CE1  . PHE A 1 291 ? -24.89119 -5.14601  -24.61568 1.000 43.94627  ? 291 PHE A CE1  1 
ATOM   4368 C CE2  . PHE A 1 291 ? -24.32712 -7.46389  -24.62000 1.000 42.51502  ? 291 PHE A CE2  1 
ATOM   4369 C CZ   . PHE A 1 291 ? -24.29779 -6.22665  -25.22868 1.000 40.82176  ? 291 PHE A CZ   1 
ATOM   4370 H H    . PHE A 1 291 ? -24.44371 -7.92706  -19.87201 1.000 42.59312  ? 291 PHE A H    1 
ATOM   4371 H HA   . PHE A 1 291 ? -25.12139 -5.34668  -20.40487 1.000 44.99614  ? 291 PHE A HA   1 
ATOM   4372 H HB2  . PHE A 1 291 ? -26.43748 -7.65891  -21.34124 1.000 44.15369  ? 291 PHE A HB2  1 
ATOM   4373 H HB3  . PHE A 1 291 ? -27.05759 -6.20149  -21.47082 1.000 44.15369  ? 291 PHE A HB3  1 
ATOM   4374 H HD1  . PHE A 1 291 ? -25.92084 -4.57298  -22.98464 1.000 48.98419  ? 291 PHE A HD1  1 
ATOM   4375 H HD2  . PHE A 1 291 ? -24.97579 -8.45614  -22.99844 1.000 43.41981  ? 291 PHE A HD2  1 
ATOM   4376 H HE1  . PHE A 1 291 ? -24.87192 -4.31065  -25.02398 1.000 52.72930  ? 291 PHE A HE1  1 
ATOM   4377 H HE2  . PHE A 1 291 ? -23.92535 -8.19446  -25.03200 1.000 51.01179  ? 291 PHE A HE2  1 
ATOM   4378 H HZ   . PHE A 1 291 ? -23.87784 -6.12246  -26.05190 1.000 48.97989  ? 291 PHE A HZ   1 
ATOM   4379 N N    . THR A 1 292 ? -26.46572 -5.16504  -18.34543 1.000 32.63549  ? 292 THR A N    1 
ATOM   4380 C CA   . THR A 1 292 ? -27.37816 -5.13646  -17.21695 1.000 40.93654  ? 292 THR A CA   1 
ATOM   4381 C C    . THR A 1 292 ? -28.81877 -5.17079  -17.71743 1.000 35.70115  ? 292 THR A C    1 
ATOM   4382 O O    . THR A 1 292 ? -29.08776 -4.92831  -18.89810 1.000 28.59956  ? 292 THR A O    1 
ATOM   4383 C CB   . THR A 1 292 ? -27.14722 -3.89325  -16.36230 1.000 33.55312  ? 292 THR A CB   1 
ATOM   4384 O OG1  . THR A 1 292 ? -27.53766 -2.72165  -17.08956 1.000 34.11414  ? 292 THR A OG1  1 
ATOM   4385 C CG2  . THR A 1 292 ? -25.68112 -3.78789  -15.95714 1.000 35.79894  ? 292 THR A CG2  1 
ATOM   4386 H H    . THR A 1 292 ? -26.09966 -4.41309  -18.54586 1.000 39.15636  ? 292 THR A H    1 
ATOM   4387 H HA   . THR A 1 292 ? -27.22132 -5.90814  -16.65054 1.000 49.11762  ? 292 THR A HA   1 
ATOM   4388 H HB   . THR A 1 292 ? -27.68019 -3.95302  -15.55405 1.000 40.25751  ? 292 THR A HB   1 
ATOM   4389 H HG1  . THR A 1 292 ? -28.35194 -2.56115  -16.96001 1.000 40.93074  ? 292 THR A HG1  1 
ATOM   4390 H HG21 . THR A 1 292 ? -25.37610 -4.63341  -15.59252 1.000 42.95250  ? 292 THR A HG21 1 
ATOM   4391 H HG22 . THR A 1 292 ? -25.13871 -3.56418  -16.72958 1.000 42.95250  ? 292 THR A HG22 1 
ATOM   4392 H HG23 . THR A 1 292 ? -25.57151 -3.09729  -15.28486 1.000 42.95250  ? 292 THR A HG23 1 
ATOM   4393 N N    . PRO A 1 293 ? -29.76608 -5.50521  -16.84016 1.000 33.70082  ? 293 PRO A N    1 
ATOM   4394 C CA   . PRO A 1 293 ? -31.18028 -5.38424  -17.22479 1.000 33.30766  ? 293 PRO A CA   1 
ATOM   4395 C C    . PRO A 1 293 ? -31.54416 -3.98540  -17.67900 1.000 34.09004  ? 293 PRO A C    1 
ATOM   4396 O O    . PRO A 1 293 ? -32.43806 -3.82357  -18.51878 1.000 34.97834  ? 293 PRO A O    1 
ATOM   4397 C CB   . PRO A 1 293 ? -31.92397 -5.78385  -15.94314 1.000 32.55564  ? 293 PRO A CB   1 
ATOM   4398 C CG   . PRO A 1 293 ? -30.95509 -6.66415  -15.20650 1.000 35.84972  ? 293 PRO A CG   1 
ATOM   4399 C CD   . PRO A 1 293 ? -29.59716 -6.09791  -15.50210 1.000 33.73047  ? 293 PRO A CD   1 
ATOM   4400 H HA   . PRO A 1 293 ? -31.39913 -6.01857  -17.92523 1.000 39.96297  ? 293 PRO A HA   1 
ATOM   4401 H HB2  . PRO A 1 293 ? -32.14115 -4.99331  -15.42469 1.000 39.06054  ? 293 PRO A HB2  1 
ATOM   4402 H HB3  . PRO A 1 293 ? -32.73475 -6.26728  -16.16636 1.000 39.06054  ? 293 PRO A HB3  1 
ATOM   4403 H HG2  . PRO A 1 293 ? -31.14169 -6.63459  -14.25508 1.000 43.01344  ? 293 PRO A HG2  1 
ATOM   4404 H HG3  . PRO A 1 293 ? -31.02695 -7.57560  -15.53052 1.000 43.01344  ? 293 PRO A HG3  1 
ATOM   4405 H HD2  . PRO A 1 293 ? -29.35592 -5.42011  -14.85150 1.000 40.47033  ? 293 PRO A HD2  1 
ATOM   4406 H HD3  . PRO A 1 293 ? -28.92600 -6.79808  -15.51615 1.000 40.47033  ? 293 PRO A HD3  1 
ATOM   4407 N N    . PHE A 1 294 ? -30.86233 -2.96366  -17.16223 1.000 29.02111  ? 294 PHE A N    1 
ATOM   4408 C CA   . PHE A 1 294 ? -31.14393 -1.60428  -17.60552 1.000 35.49575  ? 294 PHE A CA   1 
ATOM   4409 C C    . PHE A 1 294 ? -30.58270 -1.35560  -19.00116 1.000 38.00808  ? 294 PHE A C    1 
ATOM   4410 O O    . PHE A 1 294 ? -31.23994 -0.72082  -19.83493 1.000 36.90093  ? 294 PHE A O    1 
ATOM   4411 C CB   . PHE A 1 294 ? -30.57699 -0.60936  -16.59821 1.000 42.80634  ? 294 PHE A CB   1 
ATOM   4412 C CG   . PHE A 1 294 ? -31.18408 0.75065   -16.69013 1.000 55.91345  ? 294 PHE A CG   1 
ATOM   4413 C CD1  . PHE A 1 294 ? -32.38207 1.03277   -16.05789 1.000 65.57925  ? 294 PHE A CD1  1 
ATOM   4414 C CD2  . PHE A 1 294 ? -30.55370 1.75236   -17.40133 1.000 64.09766  ? 294 PHE A CD2  1 
ATOM   4415 C CE1  . PHE A 1 294 ? -32.94293 2.29067   -16.14016 1.000 67.06348  ? 294 PHE A CE1  1 
ATOM   4416 C CE2  . PHE A 1 294 ? -31.10725 3.01296   -17.48668 1.000 66.77746  ? 294 PHE A CE2  1 
ATOM   4417 C CZ   . PHE A 1 294 ? -32.30337 3.28348   -16.85508 1.000 67.99363  ? 294 PHE A CZ   1 
ATOM   4418 H H    . PHE A 1 294 ? -30.24545 -3.03052  -16.56676 1.000 34.81910  ? 294 PHE A H    1 
ATOM   4419 H HA   . PHE A 1 294 ? -32.10380 -1.47086  -17.64738 1.000 42.58867  ? 294 PHE A HA   1 
ATOM   4420 H HB2  . PHE A 1 294 ? -30.73837 -0.94577  -15.70284 1.000 51.36138  ? 294 PHE A HB2  1 
ATOM   4421 H HB3  . PHE A 1 294 ? -29.62350 -0.51901  -16.75181 1.000 51.36138  ? 294 PHE A HB3  1 
ATOM   4422 H HD1  . PHE A 1 294 ? -32.81383 0.36742   -15.57231 1.000 78.68888  ? 294 PHE A HD1  1 
ATOM   4423 H HD2  . PHE A 1 294 ? -29.74648 1.57508   -17.82779 1.000 76.91097  ? 294 PHE A HD2  1 
ATOM   4424 H HE1  . PHE A 1 294 ? -33.75038 2.46941   -15.71476 1.000 80.46995  ? 294 PHE A HE1  1 
ATOM   4425 H HE2  . PHE A 1 294 ? -30.67453 3.67970   -17.96949 1.000 80.12673  ? 294 PHE A HE2  1 
ATOM   4426 H HZ   . PHE A 1 294 ? -32.67811 4.13282   -16.91075 1.000 81.58612  ? 294 PHE A HZ   1 
ATOM   4427 N N    . ASP A 1 295 ? -29.37491 -1.85629  -19.27734 1.000 36.82076  ? 295 ASP A N    1 
ATOM   4428 C CA   . ASP A 1 295 ? -28.81727 -1.75614  -20.62213 1.000 39.26222  ? 295 ASP A CA   1 
ATOM   4429 C C    . ASP A 1 295 ? -29.77781 -2.33145  -21.65520 1.000 36.75730  ? 295 ASP A C    1 
ATOM   4430 O O    . ASP A 1 295 ? -30.03335 -1.71842  -22.69700 1.000 39.11346  ? 295 ASP A O    1 
ATOM   4431 C CB   . ASP A 1 295 ? -27.47477 -2.48801  -20.69632 1.000 34.82574  ? 295 ASP A CB   1 
ATOM   4432 C CG   . ASP A 1 295 ? -26.44119 -1.91680  -19.74976 1.000 38.13024  ? 295 ASP A CG   1 
ATOM   4433 O OD1  . ASP A 1 295 ? -26.54916 -0.72394  -19.40014 1.000 40.54093  ? 295 ASP A OD1  1 
ATOM   4434 O OD2  . ASP A 1 295 ? -25.51739 -2.66213  -19.35970 1.000 35.64239  ? 295 ASP A OD2  1 
ATOM   4435 H H    . ASP A 1 295 ? -28.86621 -2.25353  -18.70899 1.000 44.17868  ? 295 ASP A H    1 
ATOM   4436 H HA   . ASP A 1 295 ? -28.66594 -0.81916  -20.82232 1.000 47.10843  ? 295 ASP A HA   1 
ATOM   4437 H HB2  . ASP A 1 295 ? -27.61011 -3.42024  -20.46498 1.000 41.78466  ? 295 ASP A HB2  1 
ATOM   4438 H HB3  . ASP A 1 295 ? -27.12605 -2.41738  -21.59872 1.000 41.78466  ? 295 ASP A HB3  1 
ATOM   4439 N N    . VAL A 1 296 ? -30.31948 -3.51884  -21.37770 1.000 33.76132  ? 296 VAL A N    1 
ATOM   4440 C CA   . VAL A 1 296 ? -31.16082 -4.20604  -22.35431 1.000 41.49777  ? 296 VAL A CA   1 
ATOM   4441 C C    . VAL A 1 296 ? -32.42384 -3.39800  -22.63129 1.000 41.16452  ? 296 VAL A C    1 
ATOM   4442 O O    . VAL A 1 296 ? -32.80876 -3.19303  -23.78893 1.000 40.27760  ? 296 VAL A O    1 
ATOM   4443 C CB   . VAL A 1 296 ? -31.48627 -5.62892  -21.86404 1.000 30.35822  ? 296 VAL A CB   1 
ATOM   4444 C CG1  . VAL A 1 296 ? -32.50575 -6.28529  -22.76647 1.000 32.77562  ? 296 VAL A CG1  1 
ATOM   4445 C CG2  . VAL A 1 296 ? -30.22171 -6.46593  -21.80433 1.000 35.27944  ? 296 VAL A CG2  1 
ATOM   4446 H H    . VAL A 1 296 ? -30.21575 -3.94380  -20.63726 1.000 40.50736  ? 296 VAL A H    1 
ATOM   4447 H HA   . VAL A 1 296 ? -30.67313 -4.28078  -23.18945 1.000 49.79110  ? 296 VAL A HA   1 
ATOM   4448 H HB   . VAL A 1 296 ? -31.86356 -5.57268  -20.97219 1.000 36.42363  ? 296 VAL A HB   1 
ATOM   4449 H HG11 . VAL A 1 296 ? -32.35708 -7.24383  -22.76618 1.000 39.32452  ? 296 VAL A HG11 1 
ATOM   4450 H HG12 . VAL A 1 296 ? -33.39534 -6.08844  -22.43363 1.000 39.32452  ? 296 VAL A HG12 1 
ATOM   4451 H HG13 . VAL A 1 296 ? -32.40386 -5.93503  -23.66527 1.000 39.32452  ? 296 VAL A HG13 1 
ATOM   4452 H HG21 . VAL A 1 296 ? -29.87749 -6.58265  -22.70366 1.000 42.32909  ? 296 VAL A HG21 1 
ATOM   4453 H HG22 . VAL A 1 296 ? -29.56559 -6.00814  -21.25584 1.000 42.32909  ? 296 VAL A HG22 1 
ATOM   4454 H HG23 . VAL A 1 296 ? -30.43263 -7.32951  -21.41621 1.000 42.32909  ? 296 VAL A HG23 1 
ATOM   4455 N N    . VAL A 1 297 ? -33.08146 -2.91722  -21.57310 1.000 35.99380  ? 297 VAL A N    1 
ATOM   4456 C CA   . VAL A 1 297 ? -34.27741 -2.09364  -21.74659 1.000 44.40612  ? 297 VAL A CA   1 
ATOM   4457 C C    . VAL A 1 297 ? -33.95614 -0.84932  -22.56832 1.000 44.94324  ? 297 VAL A C    1 
ATOM   4458 O O    . VAL A 1 297 ? -34.70618 -0.47372  -23.47746 1.000 50.04032  ? 297 VAL A O    1 
ATOM   4459 C CB   . VAL A 1 297 ? -34.87413 -1.71785  -20.37786 1.000 42.42310  ? 297 VAL A CB   1 
ATOM   4460 C CG1  . VAL A 1 297 ? -35.97990 -0.68104  -20.54446 1.000 33.63350  ? 297 VAL A CG1  1 
ATOM   4461 C CG2  . VAL A 1 297 ? -35.39639 -2.95361  -19.67083 1.000 40.23094  ? 297 VAL A CG2  1 
ATOM   4462 H H    . VAL A 1 297 ? -32.85796 -3.05209  -20.75368 1.000 43.18634  ? 297 VAL A H    1 
ATOM   4463 H HA   . VAL A 1 297 ? -34.93599 -2.61321  -22.23365 1.000 53.28112  ? 297 VAL A HA   1 
ATOM   4464 H HB   . VAL A 1 297 ? -34.17796 -1.32770  -19.82647 1.000 50.90149  ? 297 VAL A HB   1 
ATOM   4465 H HG11 . VAL A 1 297 ? -36.48991 -0.88880  -21.34298 1.000 40.35397  ? 297 VAL A HG11 1 
ATOM   4466 H HG12 . VAL A 1 297 ? -36.55822 -0.70828  -19.76619 1.000 40.35397  ? 297 VAL A HG12 1 
ATOM   4467 H HG13 . VAL A 1 297 ? -35.57856 0.19810   -20.62772 1.000 40.35397  ? 297 VAL A HG13 1 
ATOM   4468 H HG21 . VAL A 1 297 ? -35.35215 -3.70788  -20.27912 1.000 48.27090  ? 297 VAL A HG21 1 
ATOM   4469 H HG22 . VAL A 1 297 ? -34.84783 -3.12604  -18.88965 1.000 48.27090  ? 297 VAL A HG22 1 
ATOM   4470 H HG23 . VAL A 1 297 ? -36.31547 -2.79892  -19.40202 1.000 48.27090  ? 297 VAL A HG23 1 
ATOM   4471 N N    . ARG A 1 298 ? -32.84554 -0.17864  -22.24853 1.000 41.28396  ? 298 ARG A N    1 
ATOM   4472 C CA   . ARG A 1 298 ? -32.45941 1.01029   -23.00326 1.000 43.70240  ? 298 ARG A CA   1 
ATOM   4473 C C    . ARG A 1 298 ? -32.32938 0.70053   -24.48828 1.000 41.30908  ? 298 ARG A C    1 
ATOM   4474 O O    . ARG A 1 298 ? -32.89069 1.40447   -25.33433 1.000 46.25493  ? 298 ARG A O    1 
ATOM   4475 C CB   . ARG A 1 298 ? -31.13972 1.57693   -22.47537 1.000 39.85592  ? 298 ARG A CB   1 
ATOM   4476 C CG   . ARG A 1 298 ? -31.28863 2.71305   -21.48050 1.000 56.10690  ? 298 ARG A CG   1 
ATOM   4477 C CD   . ARG A 1 298 ? -30.02263 3.56645   -21.40974 1.000 72.01043  ? 298 ARG A CD   1 
ATOM   4478 N NE   . ARG A 1 298 ? -29.38936 3.51636   -20.09625 1.000 60.31475  ? 298 ARG A NE   1 
ATOM   4479 C CZ   . ARG A 1 298 ? -28.40764 2.68931   -19.75899 1.000 56.23274  ? 298 ARG A CZ   1 
ATOM   4480 N NH1  . ARG A 1 298 ? -27.92096 1.80382   -20.61476 1.000 52.23874  ? 298 ARG A NH1  1 
ATOM   4481 N NH2  . ARG A 1 298 ? -27.89759 2.75638   -18.53272 1.000 60.56556  ? 298 ARG A NH2  1 
ATOM   4482 H H    . ARG A 1 298 ? -32.30918 -0.38898  -21.61005 1.000 49.53452  ? 298 ARG A H    1 
ATOM   4483 H HA   . ARG A 1 298 ? -33.15011 1.68052   -22.88232 1.000 52.43665  ? 298 ARG A HA   1 
ATOM   4484 H HB2  . ARG A 1 298 ? -30.65333 0.86364   -22.03317 1.000 47.82087  ? 298 ARG A HB2  1 
ATOM   4485 H HB3  . ARG A 1 298 ? -30.62619 1.91242   -23.22679 1.000 47.82087  ? 298 ARG A HB3  1 
ATOM   4486 H HG2  . ARG A 1 298 ? -32.02539 3.28280   -21.75155 1.000 67.32205  ? 298 ARG A HG2  1 
ATOM   4487 H HG3  . ARG A 1 298 ? -31.45921 2.34727   -20.59845 1.000 67.32205  ? 298 ARG A HG3  1 
ATOM   4488 H HD2  . ARG A 1 298 ? -29.38430 3.24227   -22.06423 1.000 86.40629  ? 298 ARG A HD2  1 
ATOM   4489 H HD3  . ARG A 1 298 ? -30.25139 4.48997   -21.59860 1.000 86.40629  ? 298 ARG A HD3  1 
ATOM   4490 H HE   . ARG A 1 298 ? -29.67319 4.06316   -19.49622 1.000 72.37147  ? 298 ARG A HE   1 
ATOM   4491 H HH11 . ARG A 1 298 ? -28.24131 1.75460   -21.41134 1.000 62.68026  ? 298 ARG A HH11 1 
ATOM   4492 H HH12 . ARG A 1 298 ? -27.28451 1.27793   -20.37398 1.000 62.68026  ? 298 ARG A HH12 1 
ATOM   4493 H HH21 . ARG A 1 298 ? -28.20415 3.33023   -17.97029 1.000 72.67244  ? 298 ARG A HH21 1 
ATOM   4494 H HH22 . ARG A 1 298 ? -27.26119 2.22590   -18.30210 1.000 72.67244  ? 298 ARG A HH22 1 
ATOM   4495 N N    . GLN A 1 299 ? -31.57662 -0.34657  -24.82583 1.000 49.27005  ? 299 GLN A N    1 
ATOM   4496 C CA   . GLN A 1 299 ? -31.28245 -0.60578  -26.22841 1.000 48.34519  ? 299 GLN A CA   1 
ATOM   4497 C C    . GLN A 1 299 ? -32.51545 -1.07500  -26.98847 1.000 50.73939  ? 299 GLN A C    1 
ATOM   4498 O O    . GLN A 1 299 ? -32.62386 -0.83305  -28.19552 1.000 56.82178  ? 299 GLN A O    1 
ATOM   4499 C CB   . GLN A 1 299 ? -30.16192 -1.63693  -26.34696 1.000 42.92636  ? 299 GLN A CB   1 
ATOM   4500 C CG   . GLN A 1 299 ? -29.56636 -1.70742  -27.74284 1.000 41.82170  ? 299 GLN A CG   1 
ATOM   4501 C CD   . GLN A 1 299 ? -28.36525 -2.62973  -27.84396 1.000 36.36559  ? 299 GLN A CD   1 
ATOM   4502 O OE1  . GLN A 1 299 ? -28.18407 -3.30274  -28.85596 1.000 38.66679  ? 299 GLN A OE1  1 
ATOM   4503 N NE2  . GLN A 1 299 ? -27.53147 -2.65495  -26.80447 1.000 39.03403  ? 299 GLN A NE2  1 
ATOM   4504 H H    . GLN A 1 299 ? -31.23275 -0.90837  -24.27289 1.000 59.11783  ? 299 GLN A H    1 
ATOM   4505 H HA   . GLN A 1 299 ? -30.97723 0.21883   -26.63799 1.000 58.00799  ? 299 GLN A HA   1 
ATOM   4506 H HB2  . GLN A 1 299 ? -29.45142 -1.40217  -25.72972 1.000 51.50540  ? 299 GLN A HB2  1 
ATOM   4507 H HB3  . GLN A 1 299 ? -30.51581 -2.51306  -26.12774 1.000 51.50540  ? 299 GLN A HB3  1 
ATOM   4508 H HG2  . GLN A 1 299 ? -30.24343 -2.03396  -28.35591 1.000 50.17981  ? 299 GLN A HG2  1 
ATOM   4509 H HG3  . GLN A 1 299 ? -29.28085 -0.81871  -28.00660 1.000 50.17981  ? 299 GLN A HG3  1 
ATOM   4510 H HE21 . GLN A 1 299 ? -27.68640 -2.16214  -26.11691 1.000 46.83461  ? 299 GLN A HE21 1 
ATOM   4511 H HE22 . GLN A 1 299 ? -26.83854 -3.16403  -26.82130 1.000 46.83461  ? 299 GLN A HE22 1 
ATOM   4512 N N    . CYS A 1 300 ? -33.45225 -1.73405  -26.31250 1.000 46.58955  ? 300 CYS A N    1 
ATOM   4513 C CA   . CYS A 1 300 ? -34.64192 -2.24588  -26.97787 1.000 56.67155  ? 300 CYS A CA   1 
ATOM   4514 C C    . CYS A 1 300 ? -35.79040 -1.24249  -27.00975 1.000 55.64855  ? 300 CYS A C    1 
ATOM   4515 O O    . CYS A 1 300 ? -36.74453 -1.44500  -27.76889 1.000 56.03352  ? 300 CYS A O    1 
ATOM   4516 C CB   . CYS A 1 300 ? -35.09393 -3.54606  -26.30251 1.000 49.85218  ? 300 CYS A CB   1 
ATOM   4517 S SG   . CYS A 1 300 ? -33.86967 -4.88105  -26.42251 1.000 59.79400  ? 300 CYS A SG   1 
ATOM   4518 H H    . CYS A 1 300 ? -33.42018 -1.89647  -25.46859 1.000 55.90123  ? 300 CYS A H    1 
ATOM   4519 H HA   . CYS A 1 300 ? -34.42409 -2.45497  -27.89967 1.000 67.99963  ? 300 CYS A HA   1 
ATOM   4520 H HB2  . CYS A 1 300 ? -35.25352 -3.37157  -25.36178 1.000 59.81639  ? 300 CYS A HB2  1 
ATOM   4521 H HB3  . CYS A 1 300 ? -35.91102 -3.85186  -26.72649 1.000 59.81639  ? 300 CYS A HB3  1 
ATOM   4522 H HG   . CYS A 1 300 ? -34.32071 -5.87139  -25.91676 1.000 71.74657  ? 300 CYS A HG   1 
ATOM   4523 N N    . SER A 1 301 ? -35.71947 -0.15964  -26.22994 1.000 50.97156  ? 301 SER A N    1 
ATOM   4524 C CA   . SER A 1 301 ? -36.74858 0.87113   -26.25774 1.000 52.42524  ? 301 SER A CA   1 
ATOM   4525 C C    . SER A 1 301 ? -36.30441 2.16246   -26.93029 1.000 60.08562  ? 301 SER A C    1 
ATOM   4526 O O    . SER A 1 301 ? -37.15972 2.98700   -27.26865 1.000 61.86862  ? 301 SER A O    1 
ATOM   4527 C CB   . SER A 1 301 ? -37.21637 1.20113   -24.83297 1.000 51.59707  ? 301 SER A CB   1 
ATOM   4528 O OG   . SER A 1 301 ? -36.21854 1.91742   -24.12797 1.000 65.55918  ? 301 SER A OG   1 
ATOM   4529 H H    . SER A 1 301 ? -35.08080 -0.00286  -25.67574 1.000 61.15964  ? 301 SER A H    1 
ATOM   4530 H HA   . SER A 1 301 ? -37.51107 0.52719   -26.74889 1.000 62.90406  ? 301 SER A HA   1 
ATOM   4531 H HB2  . SER A 1 301 ? -38.01917 1.74337   -24.88188 1.000 61.91025  ? 301 SER A HB2  1 
ATOM   4532 H HB3  . SER A 1 301 ? -37.40304 0.37373   -24.36236 1.000 61.91025  ? 301 SER A HB3  1 
ATOM   4533 H HG   . SER A 1 301 ? -35.53511 1.43862   -24.03166 1.000 78.66479  ? 301 SER A HG   1 
ATOM   4534 N N    . GLY A 1 302 ? -35.00488 2.36270   -27.12228 1.000 56.80615  ? 302 GLY A N    1 
ATOM   4535 C CA   . GLY A 1 302 ? -34.52098 3.55330   -27.79550 1.000 58.89167  ? 302 GLY A CA   1 
ATOM   4536 C C    . GLY A 1 302 ? -34.34930 4.76266   -26.90323 1.000 56.25999  ? 302 GLY A C    1 
ATOM   4537 O O    . GLY A 1 302 ? -34.63300 5.88861   -27.32946 1.000 54.66881  ? 302 GLY A O    1 
ATOM   4538 H H    . GLY A 1 302 ? -34.38508 1.82210   -26.87089 1.000 68.16115  ? 302 GLY A H    1 
ATOM   4539 H HA2  . GLY A 1 302 ? -33.65939 3.35597   -28.19504 1.000 70.66377  ? 302 GLY A HA2  1 
ATOM   4540 H HA3  . GLY A 1 302 ? -35.14761 3.79006   -28.49706 1.000 70.66377  ? 302 GLY A HA3  1 
ATOM   4541 N N    . VAL A 1 303 ? -33.89225 4.56440   -25.66669 1.000 49.57694  ? 303 VAL A N    1 
ATOM   4542 C CA   . VAL A 1 303 ? -33.67006 5.68765   -24.76631 1.000 59.33901  ? 303 VAL A CA   1 
ATOM   4543 C C    . VAL A 1 303 ? -32.52677 6.54358   -25.29643 1.000 65.42919  ? 303 VAL A C    1 
ATOM   4544 O O    . VAL A 1 303 ? -31.57330 6.04369   -25.91008 1.000 66.06771  ? 303 VAL A O    1 
ATOM   4545 C CB   . VAL A 1 303 ? -33.38291 5.18838   -23.33867 1.000 54.70789  ? 303 VAL A CB   1 
ATOM   4546 C CG1  . VAL A 1 303 ? -32.64987 6.24600   -22.53024 1.000 57.69683  ? 303 VAL A CG1  1 
ATOM   4547 C CG2  . VAL A 1 303 ? -34.68187 4.79563   -22.64718 1.000 60.25550  ? 303 VAL A CG2  1 
ATOM   4548 H H    . VAL A 1 303 ? -33.70545 3.79537   -25.33009 1.000 59.48610  ? 303 VAL A H    1 
ATOM   4549 H HA   . VAL A 1 303 ? -34.47052 6.23455   -24.73365 1.000 71.20058  ? 303 VAL A HA   1 
ATOM   4550 H HB   . VAL A 1 303 ? -32.81177 4.40618   -23.39214 1.000 65.64324  ? 303 VAL A HB   1 
ATOM   4551 H HG11 . VAL A 1 303 ? -32.67600 6.00080   -21.59211 1.000 69.22997  ? 303 VAL A HG11 1 
ATOM   4552 H HG12 . VAL A 1 303 ? -31.72993 6.29435   -22.83400 1.000 69.22997  ? 303 VAL A HG12 1 
ATOM   4553 H HG13 . VAL A 1 303 ? -33.08670 7.10221   -22.66063 1.000 69.22997  ? 303 VAL A HG13 1 
ATOM   4554 H HG21 . VAL A 1 303 ? -34.49406 4.58295   -21.71961 1.000 72.30037  ? 303 VAL A HG21 1 
ATOM   4555 H HG22 . VAL A 1 303 ? -35.30330 5.53876   -22.69688 1.000 72.30037  ? 303 VAL A HG22 1 
ATOM   4556 H HG23 . VAL A 1 303 ? -35.05624 4.02086   -23.09493 1.000 72.30037  ? 303 VAL A HG23 1 
ATOM   4557 N N    . THR A 1 304 ? -32.61840 7.84788   -25.05009 1.000 61.68253  ? 304 THR A N    1 
ATOM   4558 C CA   . THR A 1 304 ? -31.70596 8.82395   -25.62322 1.000 60.58473  ? 304 THR A CA   1 
ATOM   4559 C C    . THR A 1 304 ? -31.21168 9.77005   -24.53439 1.000 61.69721  ? 304 THR A C    1 
ATOM   4560 O O    . THR A 1 304 ? -31.65186 9.71389   -23.38288 1.000 64.00908  ? 304 THR A O    1 
ATOM   4561 C CB   . THR A 1 304 ? -32.38759 9.59863   -26.76174 1.000 59.14539  ? 304 THR A CB   1 
ATOM   4562 O OG1  . THR A 1 304 ? -31.49651 10.60223  -27.25452 1.000 66.16790  ? 304 THR A OG1  1 
ATOM   4563 C CG2  . THR A 1 304 ? -33.68805 10.24607  -26.28863 1.000 53.32310  ? 304 THR A CG2  1 
ATOM   4564 H H    . THR A 1 304 ? -33.21708 8.19693   -24.54083 1.000 74.01281  ? 304 THR A H    1 
ATOM   4565 H HA   . THR A 1 304 ? -30.92698 8.37253   -25.98421 1.000 72.69545  ? 304 THR A HA   1 
ATOM   4566 H HB   . THR A 1 304 ? -32.61108 8.98466   -27.47867 1.000 70.96823  ? 304 THR A HB   1 
ATOM   4567 H HG1  . THR A 1 304 ? -30.88493 10.24626  -27.70713 1.000 79.39525  ? 304 THR A HG1  1 
ATOM   4568 H HG21 . THR A 1 304 ? -34.13457 10.67690  -27.03423 1.000 63.98150  ? 304 THR A HG21 1 
ATOM   4569 H HG22 . THR A 1 304 ? -34.27755 9.57218   -25.91545 1.000 63.98150  ? 304 THR A HG22 1 
ATOM   4570 H HG23 . THR A 1 304 ? -33.49922 10.91090  -25.60802 1.000 63.98150  ? 304 THR A HG23 1 
ATOM   4571 N N    . PHE A 1 305 ? -30.27683 10.64213  -24.91038 1.000 57.79946  ? 305 PHE A N    1 
ATOM   4572 C CA   . PHE A 1 305 ? -29.62195 11.53778  -23.95718 1.000 63.08095  ? 305 PHE A CA   1 
ATOM   4573 C C    . PHE A 1 305 ? -29.50620 12.95677  -24.50977 1.000 64.36037  ? 305 PHE A C    1 
ATOM   4574 O O    . PHE A 1 305 ? -29.22860 13.15641  -25.69363 1.000 68.77954  ? 305 PHE A O    1 
ATOM   4575 C CB   . PHE A 1 305 ? -28.23449 10.99389  -23.59469 1.000 60.36552  ? 305 PHE A CB   1 
ATOM   4576 C CG   . PHE A 1 305 ? -28.25241 9.55953   -23.15672 1.000 46.92171  ? 305 PHE A CG   1 
ATOM   4577 C CD1  . PHE A 1 305 ? -28.63386 9.22213   -21.86987 1.000 48.23325  ? 305 PHE A CD1  1 
ATOM   4578 C CD2  . PHE A 1 305 ? -27.91052 8.54684   -24.03686 1.000 54.06090  ? 305 PHE A CD2  1 
ATOM   4579 C CE1  . PHE A 1 305 ? -28.66616 7.90372   -21.46457 1.000 44.01740  ? 305 PHE A CE1  1 
ATOM   4580 C CE2  . PHE A 1 305 ? -27.94000 7.22552   -23.63734 1.000 45.41012  ? 305 PHE A CE2  1 
ATOM   4581 C CZ   . PHE A 1 305 ? -28.32033 6.90429   -22.34920 1.000 52.01585  ? 305 PHE A CZ   1 
ATOM   4582 H H    . PHE A 1 305 ? -30.00131 10.73566  -25.71966 1.000 69.35312  ? 305 PHE A H    1 
ATOM   4583 H HA   . PHE A 1 305 ? -30.15527 11.58416  -23.14828 1.000 75.69091  ? 305 PHE A HA   1 
ATOM   4584 H HB2  . PHE A 1 305 ? -27.65899 11.06023  -24.37271 1.000 72.43240  ? 305 PHE A HB2  1 
ATOM   4585 H HB3  . PHE A 1 305 ? -27.87108 11.52260  -22.86717 1.000 72.43240  ? 305 PHE A HB3  1 
ATOM   4586 H HD1  . PHE A 1 305 ? -28.87142 9.89258   -21.27074 1.000 57.87367  ? 305 PHE A HD1  1 
ATOM   4587 H HD2  . PHE A 1 305 ? -27.65829 8.75892   -24.90652 1.000 64.86685  ? 305 PHE A HD2  1 
ATOM   4588 H HE1  . PHE A 1 305 ? -28.92076 7.68951   -20.59613 1.000 52.81466  ? 305 PHE A HE1  1 
ATOM   4589 H HE2  . PHE A 1 305 ? -27.70412 6.55294   -24.23475 1.000 54.48592  ? 305 PHE A HE2  1 
ATOM   4590 H HZ   . PHE A 1 305 ? -28.34317 6.01478   -22.07871 1.000 62.41280  ? 305 PHE A HZ   1 
ATOM   4591 N N    . SER B 1 1   ? -2.47782  -3.73134  -22.19435 1.000 51.18787  ? 1   SER B N    1 
ATOM   4592 C CA   . SER B 1 1   ? -2.93374  -5.05125  -22.71641 1.000 36.77829  ? 1   SER B CA   1 
ATOM   4593 C C    . SER B 1 1   ? -4.45452  -5.16264  -22.65296 1.000 44.13249  ? 1   SER B C    1 
ATOM   4594 O O    . SER B 1 1   ? -5.12518  -4.33445  -22.03541 1.000 38.68381  ? 1   SER B O    1 
ATOM   4595 C CB   . SER B 1 1   ? -2.27356  -6.18516  -21.93235 1.000 47.70332  ? 1   SER B CB   1 
ATOM   4596 O OG   . SER B 1 1   ? -2.88030  -7.43302  -22.21795 1.000 63.97071  ? 1   SER B OG   1 
ATOM   4597 H H1   . SER B 1 1   ? -2.92477  -3.07983  -22.60408 1.000 61.41921  ? 1   SER B H1   1 
ATOM   4598 H H2   . SER B 1 1   ? -2.62999  -3.69016  -21.31843 1.000 61.41921  ? 1   SER B H2   1 
ATOM   4599 H H3   . SER B 1 1   ? -1.60653  -3.63610  -22.34891 1.000 61.41921  ? 1   SER B H3   1 
ATOM   4600 H HA   . SER B 1 1   ? -2.67088  -5.14247  -23.64565 1.000 44.12772  ? 1   SER B HA   1 
ATOM   4601 H HB2  . SER B 1 1   ? -1.33557  -6.22972  -22.17543 1.000 57.23776  ? 1   SER B HB2  1 
ATOM   4602 H HB3  . SER B 1 1   ? -2.36215  -6.00334  -20.98367 1.000 57.23776  ? 1   SER B HB3  1 
ATOM   4603 H HG   . SER B 1 1   ? -2.53422  -8.03550  -21.74588 1.000 76.75863  ? 1   SER B HG   1 
ATOM   4604 N N    . GLY B 1 2   ? -4.99142  -6.18436  -23.30679 1.000 46.61139  ? 2   GLY B N    1 
ATOM   4605 C CA   . GLY B 1 2   ? -6.41924  -6.31520  -23.48988 1.000 37.53725  ? 2   GLY B CA   1 
ATOM   4606 C C    . GLY B 1 2   ? -6.84255  -5.93121  -24.89829 1.000 34.87094  ? 2   GLY B C    1 
ATOM   4607 O O    . GLY B 1 2   ? -6.13287  -5.23657  -25.62915 1.000 44.85433  ? 2   GLY B O    1 
ATOM   4608 H H    . GLY B 1 2   ? -4.53678  -6.82412  -23.65838 1.000 55.92744  ? 2   GLY B H    1 
ATOM   4609 H HA2  . GLY B 1 2   ? -6.68358  -7.23434  -23.32800 1.000 45.03847  ? 2   GLY B HA2  1 
ATOM   4610 H HA3  . GLY B 1 2   ? -6.88054  -5.73849  -22.86098 1.000 45.03847  ? 2   GLY B HA3  1 
ATOM   4611 N N    . PHE B 1 3   ? -8.02557  -6.40046  -25.28950 1.000 34.94833  ? 3   PHE B N    1 
ATOM   4612 C CA   . PHE B 1 3   ? -8.52949  -6.12634  -26.63176 1.000 30.80736  ? 3   PHE B CA   1 
ATOM   4613 C C    . PHE B 1 3   ? -10.04756 -6.07513  -26.60774 1.000 31.20724  ? 3   PHE B C    1 
ATOM   4614 O O    . PHE B 1 3   ? -10.70080 -7.05124  -26.22730 1.000 38.69701  ? 3   PHE B O    1 
ATOM   4615 C CB   . PHE B 1 3   ? -8.04995  -7.17559  -27.63507 1.000 33.65016  ? 3   PHE B CB   1 
ATOM   4616 C CG   . PHE B 1 3   ? -8.05425  -6.68576  -29.05524 1.000 31.98686  ? 3   PHE B CG   1 
ATOM   4617 C CD1  . PHE B 1 3   ? -7.07730  -5.80770  -29.49486 1.000 33.53502  ? 3   PHE B CD1  1 
ATOM   4618 C CD2  . PHE B 1 3   ? -9.04098  -7.08321  -29.94310 1.000 35.83124  ? 3   PHE B CD2  1 
ATOM   4619 C CE1  . PHE B 1 3   ? -7.07639  -5.34045  -30.79393 1.000 35.73873  ? 3   PHE B CE1  1 
ATOM   4620 C CE2  . PHE B 1 3   ? -9.04416  -6.62314  -31.24835 1.000 34.75990  ? 3   PHE B CE2  1 
ATOM   4621 C CZ   . PHE B 1 3   ? -8.06123  -5.75013  -31.67376 1.000 41.08828  ? 3   PHE B CZ   1 
ATOM   4622 H H    . PHE B 1 3   ? -8.54961  -6.87546  -24.80026 1.000 41.93177  ? 3   PHE B H    1 
ATOM   4623 H HA   . PHE B 1 3   ? -8.20242  -5.25604  -26.90834 1.000 36.96260  ? 3   PHE B HA   1 
ATOM   4624 H HB2  . PHE B 1 3   ? -7.14161  -7.43170  -27.41098 1.000 40.37396  ? 3   PHE B HB2  1 
ATOM   4625 H HB3  . PHE B 1 3   ? -8.63449  -7.94803  -27.58454 1.000 40.37396  ? 3   PHE B HB3  1 
ATOM   4626 H HD1  . PHE B 1 3   ? -6.41286  -5.52910  -28.90682 1.000 40.23580  ? 3   PHE B HD1  1 
ATOM   4627 H HD2  . PHE B 1 3   ? -9.70825  -7.66535  -29.65888 1.000 42.99126  ? 3   PHE B HD2  1 
ATOM   4628 H HE1  . PHE B 1 3   ? -6.41469  -4.75130  -31.07671 1.000 42.88025  ? 3   PHE B HE1  1 
ATOM   4629 H HE2  . PHE B 1 3   ? -9.70704  -6.90121  -31.83841 1.000 41.70565  ? 3   PHE B HE2  1 
ATOM   4630 H HZ   . PHE B 1 3   ? -8.06206  -5.43874  -32.55007 1.000 49.29970  ? 3   PHE B HZ   1 
ATOM   4631 N N    . ARG B 1 4   ? -10.59578 -4.94374  -27.04377 1.000 32.13870  ? 4   ARG B N    1 
ATOM   4632 C CA   . ARG B 1 4   ? -12.02018 -4.66443  -26.98272 1.000 35.24763  ? 4   ARG B CA   1 
ATOM   4633 C C    . ARG B 1 4   ? -12.50316 -4.14953  -28.32814 1.000 36.29254  ? 4   ARG B C    1 
ATOM   4634 O O    . ARG B 1 4   ? -11.75947 -3.49118  -29.06045 1.000 41.08045  ? 4   ARG B O    1 
ATOM   4635 C CB   . ARG B 1 4   ? -12.33846 -3.60929  -25.91784 1.000 30.96255  ? 4   ARG B CB   1 
ATOM   4636 C CG   . ARG B 1 4   ? -12.44507 -4.13605  -24.51088 1.000 37.10019  ? 4   ARG B CG   1 
ATOM   4637 C CD   . ARG B 1 4   ? -13.81111 -4.73962  -24.27077 1.000 42.07172  ? 4   ARG B CD   1 
ATOM   4638 N NE   . ARG B 1 4   ? -14.02365 -5.06612  -22.86741 1.000 45.37898  ? 4   ARG B NE   1 
ATOM   4639 C CZ   . ARG B 1 4   ? -15.15003 -5.56692  -22.38139 1.000 48.23955  ? 4   ARG B CZ   1 
ATOM   4640 N NH1  . ARG B 1 4   ? -16.19044 -5.81247  -23.16200 1.000 59.67642  ? 4   ARG B NH1  1 
ATOM   4641 N NH2  . ARG B 1 4   ? -15.23524 -5.82742  -21.07996 1.000 45.33692  ? 4   ARG B NH2  1 
ATOM   4642 H H    . ARG B 1 4   ? -10.14280 -4.30077  -27.39163 1.000 38.56021  ? 4   ARG B H    1 
ATOM   4643 H HA   . ARG B 1 4   ? -12.49247 -5.48487  -26.77125 1.000 42.29093  ? 4   ARG B HA   1 
ATOM   4644 H HB2  . ARG B 1 4   ? -11.63383 -2.94271  -25.92609 1.000 37.14883  ? 4   ARG B HB2  1 
ATOM   4645 H HB3  . ARG B 1 4   ? -13.18805 -3.19672  -26.13895 1.000 37.14883  ? 4   ARG B HB3  1 
ATOM   4646 H HG2  . ARG B 1 4   ? -11.77495 -4.82301  -24.36967 1.000 44.51400  ? 4   ARG B HG2  1 
ATOM   4647 H HG3  . ARG B 1 4   ? -12.31350 -3.40987  -23.88140 1.000 44.51400  ? 4   ARG B HG3  1 
ATOM   4648 H HD2  . ARG B 1 4   ? -14.49273 -4.10448  -24.54076 1.000 50.47983  ? 4   ARG B HD2  1 
ATOM   4649 H HD3  . ARG B 1 4   ? -13.89485 -5.55598  -24.78791 1.000 50.47983  ? 4   ARG B HD3  1 
ATOM   4650 H HE   . ARG B 1 4   ? -13.37650 -4.92479  -22.31894 1.000 54.44855  ? 4   ARG B HE   1 
ATOM   4651 H HH11 . ARG B 1 4   ? -16.14441 -5.64677  -24.00463 1.000 71.60547  ? 4   ARG B HH11 1 
ATOM   4652 H HH12 . ARG B 1 4   ? -16.91245 -6.13770  -22.82653 1.000 71.60547  ? 4   ARG B HH12 1 
ATOM   4653 H HH21 . ARG B 1 4   ? -14.56435 -5.67070  -20.56523 1.000 54.39807  ? 4   ARG B HH21 1 
ATOM   4654 H HH22 . ARG B 1 4   ? -15.96123 -6.15259  -20.75315 1.000 54.39807  ? 4   ARG B HH22 1 
ATOM   4655 N N    . LYS B 1 5   ? -13.76176 -4.43905  -28.64394 1.000 36.46007  ? 5   LYS B N    1 
ATOM   4656 C CA   . LYS B 1 5   ? -14.41463 -3.76429  -29.75891 1.000 40.13829  ? 5   LYS B CA   1 
ATOM   4657 C C    . LYS B 1 5   ? -14.59260 -2.30098  -29.37007 1.000 41.11270  ? 5   LYS B C    1 
ATOM   4658 O O    . LYS B 1 5   ? -15.33913 -1.98284  -28.43830 1.000 43.56127  ? 5   LYS B O    1 
ATOM   4659 C CB   . LYS B 1 5   ? -15.74615 -4.42434  -30.09273 1.000 38.73001  ? 5   LYS B CB   1 
ATOM   4660 C CG   . LYS B 1 5   ? -16.24825 -4.06291  -31.47938 1.000 40.44436  ? 5   LYS B CG   1 
ATOM   4661 C CD   . LYS B 1 5   ? -17.30871 -5.02871  -31.97792 1.000 56.21934  ? 5   LYS B CD   1 
ATOM   4662 C CE   . LYS B 1 5   ? -16.72048 -6.13554  -32.85376 1.000 46.31934  ? 5   LYS B CE   1 
ATOM   4663 N NZ   . LYS B 1 5   ? -17.64073 -6.45175  -33.98893 1.000 66.15747  ? 5   LYS B NZ   1 
ATOM   4664 H H    . LYS B 1 5   ? -14.25155 -5.01445  -28.23332 1.000 43.74586  ? 5   LYS B H    1 
ATOM   4665 H HA   . LYS B 1 5   ? -13.86674 -3.82601  -30.55697 1.000 48.15972  ? 5   LYS B HA   1 
ATOM   4666 H HB2  . LYS B 1 5   ? -15.63981 -5.38769  -30.05318 1.000 46.46979  ? 5   LYS B HB2  1 
ATOM   4667 H HB3  . LYS B 1 5   ? -16.41144 -4.13725  -29.44785 1.000 46.46979  ? 5   LYS B HB3  1 
ATOM   4668 H HG2  . LYS B 1 5   ? -16.63684 -3.17446  -31.45561 1.000 48.52700  ? 5   LYS B HG2  1 
ATOM   4669 H HG3  . LYS B 1 5   ? -15.50502 -4.08338  -32.10234 1.000 48.52700  ? 5   LYS B HG3  1 
ATOM   4670 H HD2  . LYS B 1 5   ? -17.74277 -5.44517  -31.21697 1.000 67.45698  ? 5   LYS B HD2  1 
ATOM   4671 H HD3  . LYS B 1 5   ? -17.96034 -4.54106  -32.50564 1.000 67.45698  ? 5   LYS B HD3  1 
ATOM   4672 H HE2  . LYS B 1 5   ? -15.86981 -5.84415  -33.21757 1.000 55.57698  ? 5   LYS B HE2  1 
ATOM   4673 H HE3  . LYS B 1 5   ? -16.59697 -6.93821  -32.32333 1.000 55.57698  ? 5   LYS B HE3  1 
ATOM   4674 H HZ1  . LYS B 1 5   ? -17.63588 -5.78576  -34.57930 1.000 79.38274  ? 5   LYS B HZ1  1 
ATOM   4675 H HZ2  . LYS B 1 5   ? -17.37815 -7.19918  -34.39451 1.000 79.38274  ? 5   LYS B HZ2  1 
ATOM   4676 H HZ3  . LYS B 1 5   ? -18.47021 -6.56343  -33.68630 1.000 79.38274  ? 5   LYS B HZ3  1 
ATOM   4677 N N    . MET B 1 6   ? -13.88584 -1.41246  -30.05958 1.000 33.86123  ? 6   MET B N    1 
ATOM   4678 C CA   . MET B 1 6   ? -13.71758 -0.03307  -29.62807 1.000 36.09936  ? 6   MET B CA   1 
ATOM   4679 C C    . MET B 1 6   ? -14.20673 0.90650   -30.71628 1.000 32.76065  ? 6   MET B C    1 
ATOM   4680 O O    . MET B 1 6   ? -13.86408 0.73683   -31.89096 1.000 32.00900  ? 6   MET B O    1 
ATOM   4681 C CB   . MET B 1 6   ? -12.24879 0.24487   -29.30601 1.000 37.31407  ? 6   MET B CB   1 
ATOM   4682 C CG   . MET B 1 6   ? -11.99296 1.55310   -28.59821 1.000 43.05263  ? 6   MET B CG   1 
ATOM   4683 S SD   . MET B 1 6   ? -10.24653 1.73742   -28.17610 1.000 52.44087  ? 6   MET B SD   1 
ATOM   4684 C CE   . MET B 1 6   ? -10.04044 0.40114   -27.00155 1.000 39.56139  ? 6   MET B CE   1 
ATOM   4685 H H    . MET B 1 6   ? -13.48489 -1.59134  -30.79906 1.000 40.62725  ? 6   MET B H    1 
ATOM   4686 H HA   . MET B 1 6   ? -14.24533 0.12309   -28.82933 1.000 43.31300  ? 6   MET B HA   1 
ATOM   4687 H HB2  . MET B 1 6   ? -11.91932 -0.46573  -28.73383 1.000 44.77066  ? 6   MET B HB2  1 
ATOM   4688 H HB3  . MET B 1 6   ? -11.74897 0.26022   -30.13718 1.000 44.77066  ? 6   MET B HB3  1 
ATOM   4689 H HG2  . MET B 1 6   ? -12.24731 2.28796   -29.17802 1.000 51.65693  ? 6   MET B HG2  1 
ATOM   4690 H HG3  . MET B 1 6   ? -12.51106 1.58246   -27.77870 1.000 51.65693  ? 6   MET B HG3  1 
ATOM   4691 H HE1  . MET B 1 6   ? -10.89938 -0.02461  -26.85367 1.000 47.46744  ? 6   MET B HE1  1 
ATOM   4692 H HE2  . MET B 1 6   ? -9.41022  -0.24198  -27.36227 1.000 47.46744  ? 6   MET B HE2  1 
ATOM   4693 H HE3  . MET B 1 6   ? -9.70272  0.76314   -26.16741 1.000 47.46744  ? 6   MET B HE3  1 
ATOM   4694 N N    . ALA B 1 7   ? -15.00026 1.89359   -30.32329 1.000 34.18735  ? 7   ALA B N    1 
ATOM   4695 C CA   . ALA B 1 7   ? -15.51428 2.89395   -31.24312 1.000 36.20678  ? 7   ALA B CA   1 
ATOM   4696 C C    . ALA B 1 7   ? -14.72033 4.18769   -31.10625 1.000 31.54456  ? 7   ALA B C    1 
ATOM   4697 O O    . ALA B 1 7   ? -14.05151 4.43199   -30.09939 1.000 35.80953  ? 7   ALA B O    1 
ATOM   4698 C CB   . ALA B 1 7   ? -17.00153 3.15381   -30.98497 1.000 33.25855  ? 7   ALA B CB   1 
ATOM   4699 H H    . ALA B 1 7   ? -15.25959 2.00602   -29.51107 1.000 41.01860  ? 7   ALA B H    1 
ATOM   4700 H HA   . ALA B 1 7   ? -15.42293 2.57547   -32.15479 1.000 43.44191  ? 7   ALA B HA   1 
ATOM   4701 H HB1  . ALA B 1 7   ? -17.48176 2.31228   -31.03076 1.000 39.90403  ? 7   ALA B HB1  1 
ATOM   4702 H HB2  . ALA B 1 7   ? -17.10527 3.54635   -30.10403 1.000 39.90403  ? 7   ALA B HB2  1 
ATOM   4703 H HB3  . ALA B 1 7   ? -17.33748 3.76355   -31.66044 1.000 39.90403  ? 7   ALA B HB3  1 
ATOM   4704 N N    . PHE B 1 8   ? -14.78618 5.00921   -32.15008 1.000 33.53979  ? 8   PHE B N    1 
ATOM   4705 C CA   . PHE B 1 8   ? -14.20901 6.33961   -32.08034 1.000 34.61124  ? 8   PHE B CA   1 
ATOM   4706 C C    . PHE B 1 8   ? -15.01580 7.20857   -31.11696 1.000 39.15936  ? 8   PHE B C    1 
ATOM   4707 O O    . PHE B 1 8   ? -16.21151 6.97676   -30.91349 1.000 35.43704  ? 8   PHE B O    1 
ATOM   4708 C CB   . PHE B 1 8   ? -14.19269 6.99504   -33.45665 1.000 33.19656  ? 8   PHE B CB   1 
ATOM   4709 C CG   . PHE B 1 8   ? -13.19825 6.39752   -34.40161 1.000 35.60480  ? 8   PHE B CG   1 
ATOM   4710 C CD1  . PHE B 1 8   ? -11.88703 6.84227   -34.42304 1.000 37.16476  ? 8   PHE B CD1  1 
ATOM   4711 C CD2  . PHE B 1 8   ? -13.57256 5.39262   -35.27158 1.000 39.76528  ? 8   PHE B CD2  1 
ATOM   4712 C CE1  . PHE B 1 8   ? -10.97003 6.29202   -35.29636 1.000 37.44160  ? 8   PHE B CE1  1 
ATOM   4713 C CE2  . PHE B 1 8   ? -12.65923 4.83969   -36.14129 1.000 42.13027  ? 8   PHE B CE2  1 
ATOM   4714 C CZ   . PHE B 1 8   ? -11.35950 5.29269   -36.15879 1.000 36.47411  ? 8   PHE B CZ   1 
ATOM   4715 H H    . PHE B 1 8   ? -15.15700 4.81922   -32.90240 1.000 40.24152  ? 8   PHE B H    1 
ATOM   4716 H HA   . PHE B 1 8   ? -13.29480 6.27811   -31.76199 1.000 41.52726  ? 8   PHE B HA   1 
ATOM   4717 H HB2  . PHE B 1 8   ? -15.07190 6.90261   -33.85583 1.000 39.82965  ? 8   PHE B HB2  1 
ATOM   4718 H HB3  . PHE B 1 8   ? -13.97307 7.93400   -33.35162 1.000 39.82965  ? 8   PHE B HB3  1 
ATOM   4719 H HD1  . PHE B 1 8   ? -11.62123 7.51885   -33.84297 1.000 44.59148  ? 8   PHE B HD1  1 
ATOM   4720 H HD2  . PHE B 1 8   ? -14.45058 5.08606   -35.27012 1.000 47.71210  ? 8   PHE B HD2  1 
ATOM   4721 H HE1  . PHE B 1 8   ? -10.09113 6.59600   -35.30181 1.000 44.92369  ? 8   PHE B HE1  1 
ATOM   4722 H HE2  . PHE B 1 8   ? -12.92109 4.15876   -36.71807 1.000 50.55010  ? 8   PHE B HE2  1 
ATOM   4723 H HZ   . PHE B 1 8   ? -10.74566 4.92412   -36.75231 1.000 43.76270  ? 8   PHE B HZ   1 
ATOM   4724 N N    . PRO B 1 9   ? -14.38921 8.21944   -30.51462 1.000 35.13697  ? 9   PRO B N    1 
ATOM   4725 C CA   . PRO B 1 9   ? -15.15680 9.16802   -29.69681 1.000 40.30626  ? 9   PRO B CA   1 
ATOM   4726 C C    . PRO B 1 9   ? -16.19750 9.87559   -30.55186 1.000 34.56929  ? 9   PRO B C    1 
ATOM   4727 O O    . PRO B 1 9   ? -15.89510 10.37815  -31.63590 1.000 35.44842  ? 9   PRO B O    1 
ATOM   4728 C CB   . PRO B 1 9   ? -14.08966 10.13647  -29.16909 1.000 38.52833  ? 9   PRO B CB   1 
ATOM   4729 C CG   . PRO B 1 9   ? -12.78215 9.42172   -29.34739 1.000 38.13430  ? 9   PRO B CG   1 
ATOM   4730 C CD   . PRO B 1 9   ? -12.96116 8.57660   -30.57105 1.000 41.36507  ? 9   PRO B CD   1 
ATOM   4731 H HA   . PRO B 1 9   ? -15.58285 8.72529   -28.94623 1.000 48.36128  ? 9   PRO B HA   1 
ATOM   4732 H HB2  . PRO B 1 9   ? -14.10778 10.95816  -29.68425 1.000 46.22776  ? 9   PRO B HB2  1 
ATOM   4733 H HB3  . PRO B 1 9   ? -14.25410 10.32836  -28.23258 1.000 46.22776  ? 9   PRO B HB3  1 
ATOM   4734 H HG2  . PRO B 1 9   ? -12.06829 10.06627  -29.47338 1.000 45.75494  ? 9   PRO B HG2  1 
ATOM   4735 H HG3  . PRO B 1 9   ? -12.59853 8.87099   -28.57029 1.000 45.75494  ? 9   PRO B HG3  1 
ATOM   4736 H HD2  . PRO B 1 9   ? -12.76124 9.08214   -31.37440 1.000 49.63185  ? 9   PRO B HD2  1 
ATOM   4737 H HD3  . PRO B 1 9   ? -12.40325 7.78415   -30.53031 1.000 49.63185  ? 9   PRO B HD3  1 
ATOM   4738 N N    . SER B 1 10  ? -17.43180 9.91032   -30.05393 1.000 38.88928  ? 10  SER B N    1 
ATOM   4739 C CA   . SER B 1 10  ? -18.58108 10.35919  -30.82745 1.000 41.13386  ? 10  SER B CA   1 
ATOM   4740 C C    . SER B 1 10  ? -18.88499 11.84626  -30.66008 1.000 42.04196  ? 10  SER B C    1 
ATOM   4741 O O    . SER B 1 10  ? -19.89148 12.32043  -31.19728 1.000 38.13238  ? 10  SER B O    1 
ATOM   4742 C CB   . SER B 1 10  ? -19.81528 9.54061   -30.43661 1.000 36.13926  ? 10  SER B CB   1 
ATOM   4743 O OG   . SER B 1 10  ? -20.26885 9.88974   -29.13860 1.000 35.81328  ? 10  SER B OG   1 
ATOM   4744 H H    . SER B 1 10  ? -17.63081 9.67283   -29.25168 1.000 46.66091  ? 10  SER B H    1 
ATOM   4745 H HA   . SER B 1 10  ? -18.38985 10.20753  -31.76624 1.000 49.35441  ? 10  SER B HA   1 
ATOM   4746 H HB2  . SER B 1 10  ? -20.52409 9.71524   -31.07535 1.000 43.36088  ? 10  SER B HB2  1 
ATOM   4747 H HB3  . SER B 1 10  ? -19.58435 8.59855   -30.44662 1.000 43.36088  ? 10  SER B HB3  1 
ATOM   4748 H HG   . SER B 1 10  ? -21.00611 9.51872   -28.98243 1.000 42.96971  ? 10  SER B HG   1 
ATOM   4749 N N    . GLY B 1 11  ? -18.03496 12.59313  -29.95262 1.000 35.20015  ? 11  GLY B N    1 
ATOM   4750 C CA   . GLY B 1 11  ? -18.37544 13.96904  -29.61894 1.000 39.41205  ? 11  GLY B CA   1 
ATOM   4751 C C    . GLY B 1 11  ? -18.55526 14.85273  -30.83905 1.000 34.60987  ? 11  GLY B C    1 
ATOM   4752 O O    . GLY B 1 11  ? -19.50939 15.63081  -30.92479 1.000 37.13592  ? 11  GLY B O    1 
ATOM   4753 H H    . GLY B 1 11  ? -17.27008 12.32996  -29.66055 1.000 42.23395  ? 11  GLY B H    1 
ATOM   4754 H HA2  . GLY B 1 11  ? -19.20386 13.97815  -29.11443 1.000 47.28824  ? 11  GLY B HA2  1 
ATOM   4755 H HA3  . GLY B 1 11  ? -17.66893 14.34789  -29.07284 1.000 47.28824  ? 11  GLY B HA3  1 
ATOM   4756 N N    . LYS B 1 12  ? -17.63254 14.75272  -31.79732 1.000 32.55222  ? 12  LYS B N    1 
ATOM   4757 C CA   . LYS B 1 12  ? -17.69429 15.61228  -32.97469 1.000 33.85794  ? 12  LYS B CA   1 
ATOM   4758 C C    . LYS B 1 12  ? -18.94450 15.34844  -33.80134 1.000 35.57405  ? 12  LYS B C    1 
ATOM   4759 O O    . LYS B 1 12  ? -19.44007 16.25308  -34.48378 1.000 32.88856  ? 12  LYS B O    1 
ATOM   4760 C CB   . LYS B 1 12  ? -16.43868 15.41438  -33.82264 1.000 46.01538  ? 12  LYS B CB   1 
ATOM   4761 C CG   . LYS B 1 12  ? -15.17427 15.90526  -33.14094 1.000 49.68099  ? 12  LYS B CG   1 
ATOM   4762 C CD   . LYS B 1 12  ? -13.92789 15.50193  -33.90044 1.000 58.13335  ? 12  LYS B CD   1 
ATOM   4763 C CE   . LYS B 1 12  ? -12.69081 16.12960  -33.27632 1.000 66.30013  ? 12  LYS B CE   1 
ATOM   4764 N NZ   . LYS B 1 12  ? -11.45025 15.43524  -33.70765 1.000 68.33790  ? 12  LYS B NZ   1 
ATOM   4765 H H    . LYS B 1 12  ? -16.97098 14.20330  -31.78896 1.000 39.05644  ? 12  LYS B H    1 
ATOM   4766 H HA   . LYS B 1 12  ? -17.72327 16.53841  -32.68774 1.000 40.62330  ? 12  LYS B HA   1 
ATOM   4767 H HB2  . LYS B 1 12  ? -16.33035 14.46832  -34.00740 1.000 55.21222  ? 12  LYS B HB2  1 
ATOM   4768 H HB3  . LYS B 1 12  ? -16.54000 15.90514  -34.65317 1.000 55.21222  ? 12  LYS B HB3  1 
ATOM   4769 H HG2  . LYS B 1 12  ? -15.19584 16.87350  -33.08670 1.000 59.61096  ? 12  LYS B HG2  1 
ATOM   4770 H HG3  . LYS B 1 12  ? -15.12287 15.52416  -32.25042 1.000 59.61096  ? 12  LYS B HG3  1 
ATOM   4771 H HD2  . LYS B 1 12  ? -13.83035 14.53720  -33.87463 1.000 69.75379  ? 12  LYS B HD2  1 
ATOM   4772 H HD3  . LYS B 1 12  ? -13.99630 15.80399  -34.81967 1.000 69.75379  ? 12  LYS B HD3  1 
ATOM   4773 H HE2  . LYS B 1 12  ? -12.63039 17.05876  -33.54820 1.000 79.55393  ? 12  LYS B HE2  1 
ATOM   4774 H HE3  . LYS B 1 12  ? -12.75335 16.07003  -32.31017 1.000 79.55393  ? 12  LYS B HE3  1 
ATOM   4775 H HZ1  . LYS B 1 12  ? -11.48390 15.26622  -34.58080 1.000 81.99926  ? 12  LYS B HZ1  1 
ATOM   4776 H HZ2  . LYS B 1 12  ? -10.74123 15.94623  -33.53948 1.000 81.99926  ? 12  LYS B HZ2  1 
ATOM   4777 H HZ3  . LYS B 1 12  ? -11.36307 14.66646  -33.26778 1.000 81.99926  ? 12  LYS B HZ3  1 
ATOM   4778 N N    . VAL B 1 13  ? -19.46935 14.12811  -33.75058 1.000 33.58559  ? 13  VAL B N    1 
ATOM   4779 C CA   . VAL B 1 13  ? -20.67519 13.80070  -34.49930 1.000 36.89341  ? 13  VAL B CA   1 
ATOM   4780 C C    . VAL B 1 13  ? -21.93914 14.15328  -33.71825 1.000 35.48406  ? 13  VAL B C    1 
ATOM   4781 O O    . VAL B 1 13  ? -22.95514 14.51339  -34.32207 1.000 34.28077  ? 13  VAL B O    1 
ATOM   4782 C CB   . VAL B 1 13  ? -20.64897 12.31311  -34.88769 1.000 28.31839  ? 13  VAL B CB   1 
ATOM   4783 C CG1  . VAL B 1 13  ? -21.90682 11.93770  -35.64865 1.000 31.07435  ? 13  VAL B CG1  1 
ATOM   4784 C CG2  . VAL B 1 13  ? -19.40100 12.01586  -35.70882 1.000 29.35035  ? 13  VAL B CG2  1 
ATOM   4785 H H    . VAL B 1 13  ? -19.14768 13.47538  -33.29225 1.000 40.29648  ? 13  VAL B H    1 
ATOM   4786 H HA   . VAL B 1 13  ? -20.69691 14.32323  -35.31624 1.000 44.26586  ? 13  VAL B HA   1 
ATOM   4787 H HB   . VAL B 1 13  ? -20.62153 11.77015  -34.08436 1.000 33.97584  ? 13  VAL B HB   1 
ATOM   4788 H HG11 . VAL B 1 13  ? -22.64389 11.86200  -35.02263 1.000 37.28299  ? 13  VAL B HG11 1 
ATOM   4789 H HG12 . VAL B 1 13  ? -22.09800 12.62792  -36.30282 1.000 37.28299  ? 13  VAL B HG12 1 
ATOM   4790 H HG13 . VAL B 1 13  ? -21.76397 11.08876  -36.09565 1.000 37.28299  ? 13  VAL B HG13 1 
ATOM   4791 H HG21 . VAL B 1 13  ? -19.39777 11.07622  -35.94957 1.000 35.21419  ? 13  VAL B HG21 1 
ATOM   4792 H HG22 . VAL B 1 13  ? -19.41250 12.56256  -36.51000 1.000 35.21419  ? 13  VAL B HG22 1 
ATOM   4793 H HG23 . VAL B 1 13  ? -18.61649 12.22393  -35.17763 1.000 35.21419  ? 13  VAL B HG23 1 
ATOM   4794 N N    . GLU B 1 14  ? -21.89612 14.07179  -32.38536 1.000 35.47431  ? 14  GLU B N    1 
ATOM   4795 C CA   . GLU B 1 14  ? -23.03874 14.48371  -31.57664 1.000 36.35870  ? 14  GLU B CA   1 
ATOM   4796 C C    . GLU B 1 14  ? -23.46585 15.91009  -31.89650 1.000 41.07182  ? 14  GLU B C    1 
ATOM   4797 O O    . GLU B 1 14  ? -24.66329 16.21621  -31.92590 1.000 34.94443  ? 14  GLU B O    1 
ATOM   4798 C CB   . GLU B 1 14  ? -22.70194 14.36661  -30.09125 1.000 42.10140  ? 14  GLU B CB   1 
ATOM   4799 C CG   . GLU B 1 14  ? -22.58582 12.94466  -29.58592 1.000 45.75983  ? 14  GLU B CG   1 
ATOM   4800 C CD   . GLU B 1 14  ? -21.93992 12.87843  -28.22000 1.000 37.84830  ? 14  GLU B CD   1 
ATOM   4801 O OE1  . GLU B 1 14  ? -22.40968 13.57869  -27.30050 1.000 42.28677  ? 14  GLU B OE1  1 
ATOM   4802 O OE2  . GLU B 1 14  ? -20.94983 12.13778  -28.07127 1.000 42.69608  ? 14  GLU B OE2  1 
ATOM   4803 H H    . GLU B 1 14  ? -21.22401 13.78455  -31.93220 1.000 42.56295  ? 14  GLU B H    1 
ATOM   4804 H HA   . GLU B 1 14  ? -23.78043 13.89025  -31.77312 1.000 43.62421  ? 14  GLU B HA   1 
ATOM   4805 H HB2  . GLU B 1 14  ? -21.85150 14.80497  -29.93156 1.000 50.51546  ? 14  GLU B HB2  1 
ATOM   4806 H HB3  . GLU B 1 14  ? -23.40134 14.80324  -29.58029 1.000 50.51546  ? 14  GLU B HB3  1 
ATOM   4807 H HG2  . GLU B 1 14  ? -23.47218 12.55600  -29.52103 1.000 54.90557  ? 14  GLU B HG2  1 
ATOM   4808 H HG3  . GLU B 1 14  ? -22.04241 12.43032  -30.20322 1.000 54.90557  ? 14  GLU B HG3  1 
ATOM   4809 N N    . GLY B 1 15  ? -22.49868 16.80090  -32.12574 1.000 34.24204  ? 15  GLY B N    1 
ATOM   4810 C CA   . GLY B 1 15  ? -22.79427 18.18760  -32.43093 1.000 35.91420  ? 15  GLY B CA   1 
ATOM   4811 C C    . GLY B 1 15  ? -23.38387 18.43033  -33.80186 1.000 38.96366  ? 15  GLY B C    1 
ATOM   4812 O O    . GLY B 1 15  ? -23.65728 19.58471  -34.14649 1.000 34.90764  ? 15  GLY B O    1 
ATOM   4813 H H    . GLY B 1 15  ? -21.65837 16.61875  -32.10863 1.000 41.08422  ? 15  GLY B H    1 
ATOM   4814 H HA2  . GLY B 1 15  ? -23.42608 18.52122  -31.77487 1.000 43.09081  ? 15  GLY B HA2  1 
ATOM   4815 H HA3  . GLY B 1 15  ? -21.97328 18.70036  -32.36796 1.000 43.09081  ? 15  GLY B HA3  1 
ATOM   4816 N N    . CYS B 1 16  ? -23.57878 17.37320  -34.59115 1.000 39.30670  ? 16  CYS B N    1 
ATOM   4817 C CA   . CYS B 1 16  ? -24.14816 17.46432  -35.92611 1.000 34.50083  ? 16  CYS B CA   1 
ATOM   4818 C C    . CYS B 1 16  ? -25.49427 16.77123  -36.04954 1.000 33.46362  ? 16  CYS B C    1 
ATOM   4819 O O    . CYS B 1 16  ? -26.05208 16.72706  -37.14988 1.000 35.53995  ? 16  CYS B O    1 
ATOM   4820 C CB   . CYS B 1 16  ? -23.19056 16.85198  -36.95057 1.000 34.22523  ? 16  CYS B CB   1 
ATOM   4821 S SG   . CYS B 1 16  ? -21.55027 17.57903  -36.95520 1.000 35.64753  ? 16  CYS B SG   1 
ATOM   4822 H H    . CYS B 1 16  ? -23.38108 16.56767  -34.36389 1.000 47.16181  ? 16  CYS B H    1 
ATOM   4823 H HA   . CYS B 1 16  ? -24.26870 18.40363  -36.13602 1.000 41.39477  ? 16  CYS B HA   1 
ATOM   4824 H HB2  . CYS B 1 16  ? -23.09247 15.90672  -36.75624 1.000 41.06404  ? 16  CYS B HB2  1 
ATOM   4825 H HB3  . CYS B 1 16  ? -23.56735 16.97122  -37.83640 1.000 41.06404  ? 16  CYS B HB3  1 
ATOM   4826 H HG   . CYS B 1 16  ? -20.87232 17.00847  -37.76442 1.000 42.77081  ? 16  CYS B HG   1 
ATOM   4827 N N    . MET B 1 17  ? -26.02101 16.21004  -34.96923 1.000 36.48599  ? 17  MET B N    1 
ATOM   4828 C CA   . MET B 1 17  ? -27.27752 15.47869  -35.02755 1.000 39.49560  ? 17  MET B CA   1 
ATOM   4829 C C    . MET B 1 17  ? -28.42417 16.43634  -34.73152 1.000 41.77669  ? 17  MET B C    1 
ATOM   4830 O O    . MET B 1 17  ? -28.44289 17.08986  -33.68223 1.000 39.52028  ? 17  MET B O    1 
ATOM   4831 C CB   . MET B 1 17  ? -27.27154 14.30787  -34.04661 1.000 37.15591  ? 17  MET B CB   1 
ATOM   4832 C CG   . MET B 1 17  ? -26.16945 13.28263  -34.31610 1.000 40.50514  ? 17  MET B CG   1 
ATOM   4833 S SD   . MET B 1 17  ? -25.92564 12.89544  -36.06971 1.000 39.62591  ? 17  MET B SD   1 
ATOM   4834 C CE   . MET B 1 17  ? -27.54290 12.26721  -36.51490 1.000 35.12641  ? 17  MET B CE   1 
ATOM   4835 H H    . MET B 1 17  ? -25.66681 16.23949  -34.18611 1.000 43.77696  ? 17  MET B H    1 
ATOM   4836 H HA   . MET B 1 17  ? -27.39312 15.11157  -35.91792 1.000 47.38850  ? 17  MET B HA   1 
ATOM   4837 H HB2  . MET B 1 17  ? -27.14134 14.65347  -33.14967 1.000 44.58086  ? 17  MET B HB2  1 
ATOM   4838 H HB3  . MET B 1 17  ? -28.12382 13.84837  -34.10463 1.000 44.58086  ? 17  MET B HB3  1 
ATOM   4839 H HG2  . MET B 1 17  ? -25.33147 13.63039  -33.97295 1.000 48.59994  ? 17  MET B HG2  1 
ATOM   4840 H HG3  . MET B 1 17  ? -26.39656 12.45624  -33.86178 1.000 48.59994  ? 17  MET B HG3  1 
ATOM   4841 H HE1  . MET B 1 17  ? -27.75179 11.50552  -35.95179 1.000 42.14547  ? 17  MET B HE1  1 
ATOM   4842 H HE2  . MET B 1 17  ? -28.20114 12.96718  -36.38204 1.000 42.14547  ? 17  MET B HE2  1 
ATOM   4843 H HE3  . MET B 1 17  ? -27.53117 11.99665  -37.44633 1.000 42.14547  ? 17  MET B HE3  1 
ATOM   4844 N N    . VAL B 1 18  ? -29.37153 16.52122  -35.66453 1.000 40.84031  ? 18  VAL B N    1 
ATOM   4845 C CA   . VAL B 1 18  ? -30.56052 17.34440  -35.51531 1.000 41.88951  ? 18  VAL B CA   1 
ATOM   4846 C C    . VAL B 1 18  ? -31.78261 16.47518  -35.78222 1.000 45.59990  ? 18  VAL B C    1 
ATOM   4847 O O    . VAL B 1 18  ? -31.69032 15.37997  -36.34198 1.000 41.58105  ? 18  VAL B O    1 
ATOM   4848 C CB   . VAL B 1 18  ? -30.54633 18.56645  -36.45993 1.000 39.78489  ? 18  VAL B CB   1 
ATOM   4849 C CG1  . VAL B 1 18  ? -29.34343 19.45411  -36.17072 1.000 35.92235  ? 18  VAL B CG1  1 
ATOM   4850 C CG2  . VAL B 1 18  ? -30.53836 18.11583  -37.90921 1.000 37.21100  ? 18  VAL B CG2  1 
ATOM   4851 H H    . VAL B 1 18  ? -29.34324 16.09759  -36.41241 1.000 49.00215  ? 18  VAL B H    1 
ATOM   4852 H HA   . VAL B 1 18  ? -30.61421 17.67259  -34.60409 1.000 50.26118  ? 18  VAL B HA   1 
ATOM   4853 H HB   . VAL B 1 18  ? -31.34969 19.08822  -36.30740 1.000 47.73564  ? 18  VAL B HB   1 
ATOM   4854 H HG11 . VAL B 1 18  ? -29.33510 20.19031  -36.80227 1.000 43.10059  ? 18  VAL B HG11 1 
ATOM   4855 H HG12 . VAL B 1 18  ? -29.41330 19.79560  -35.26552 1.000 43.10059  ? 18  VAL B HG12 1 
ATOM   4856 H HG13 . VAL B 1 18  ? -28.53344 18.92873  -36.26445 1.000 43.10059  ? 18  VAL B HG13 1 
ATOM   4857 H HG21 . VAL B 1 18  ? -30.38745 18.88642  -38.47870 1.000 44.64697  ? 18  VAL B HG21 1 
ATOM   4858 H HG22 . VAL B 1 18  ? -29.82765 17.46768  -38.03450 1.000 44.64697  ? 18  VAL B HG22 1 
ATOM   4859 H HG23 . VAL B 1 18  ? -31.39501 17.71209  -38.11911 1.000 44.64697  ? 18  VAL B HG23 1 
ATOM   4860 N N    . GLN B 1 19  ? -32.93730 16.97550  -35.35821 1.000 42.18347  ? 19  GLN B N    1 
ATOM   4861 C CA   . GLN B 1 19  ? -34.21076 16.31259  -35.59421 1.000 40.94065  ? 19  GLN B CA   1 
ATOM   4862 C C    . GLN B 1 19  ? -34.83995 16.90600  -36.84631 1.000 41.41575  ? 19  GLN B C    1 
ATOM   4863 O O    . GLN B 1 19  ? -34.92864 18.13101  -36.97673 1.000 47.02140  ? 19  GLN B O    1 
ATOM   4864 C CB   . GLN B 1 19  ? -35.14378 16.48034  -34.39527 1.000 38.22963  ? 19  GLN B CB   1 
ATOM   4865 C CG   . GLN B 1 19  ? -36.43169 15.67543  -34.49144 1.000 42.30556  ? 19  GLN B CG   1 
ATOM   4866 C CD   . GLN B 1 19  ? -37.43906 16.05662  -33.42295 1.000 54.40143  ? 19  GLN B CD   1 
ATOM   4867 O OE1  . GLN B 1 19  ? -37.86461 15.21944  -32.62555 1.000 52.15320  ? 19  GLN B OE1  1 
ATOM   4868 N NE2  . GLN B 1 19  ? -37.83046 17.32642  -33.40579 1.000 58.44330  ? 19  GLN B NE2  1 
ATOM   4869 H H    . GLN B 1 19  ? -33.00868 17.71347  -34.92243 1.000 50.61393  ? 19  GLN B H    1 
ATOM   4870 H HA   . GLN B 1 19  ? -34.07344 15.36213  -35.73081 1.000 49.12255  ? 19  GLN B HA   1 
ATOM   4871 H HB2  . GLN B 1 19  ? -34.67603 16.19313  -33.59551 1.000 45.86933  ? 19  GLN B HB2  1 
ATOM   4872 H HB3  . GLN B 1 19  ? -35.38649 17.41642  -34.31954 1.000 45.86933  ? 19  GLN B HB3  1 
ATOM   4873 H HG2  . GLN B 1 19  ? -36.83887 15.83180  -35.35784 1.000 50.76044  ? 19  GLN B HG2  1 
ATOM   4874 H HG3  . GLN B 1 19  ? -36.22493 14.73347  -34.38719 1.000 50.76044  ? 19  GLN B HG3  1 
ATOM   4875 H HE21 . GLN B 1 19  ? -37.51391 17.88177  -33.98109 1.000 70.12573  ? 19  GLN B HE21 1 
ATOM   4876 H HE22 . GLN B 1 19  ? -38.40032 17.59284  -32.81937 1.000 70.12573  ? 19  GLN B HE22 1 
ATOM   4877 N N    . VAL B 1 20  ? -35.25153 16.04281  -37.77144 1.000 39.17704  ? 20  VAL B N    1 
ATOM   4878 C CA   . VAL B 1 20  ? -35.94551 16.45754  -38.98528 1.000 43.49410  ? 20  VAL B CA   1 
ATOM   4879 C C    . VAL B 1 20  ? -37.36846 15.92553  -38.91832 1.000 47.28300  ? 20  VAL B C    1 
ATOM   4880 O O    . VAL B 1 20  ? -37.58158 14.71570  -38.76589 1.000 45.09631  ? 20  VAL B O    1 
ATOM   4881 C CB   . VAL B 1 20  ? -35.24052 15.95703  -40.25354 1.000 41.03853  ? 20  VAL B CB   1 
ATOM   4882 C CG1  . VAL B 1 20  ? -35.99715 16.43344  -41.48964 1.000 42.17597  ? 20  VAL B CG1  1 
ATOM   4883 C CG2  . VAL B 1 20  ? -33.80001 16.42194  -40.27594 1.000 39.86217  ? 20  VAL B CG2  1 
ATOM   4884 H H    . VAL B 1 20  ? -35.13688 15.19232  -37.71560 1.000 47.00621  ? 20  VAL B H    1 
ATOM   4885 H HA   . VAL B 1 20  ? -35.97418 17.42671  -39.01328 1.000 52.18670  ? 20  VAL B HA   1 
ATOM   4886 H HB   . VAL B 1 20  ? -35.23353 14.98708  -40.26057 1.000 49.24001  ? 20  VAL B HB   1 
ATOM   4887 H HG11 . VAL B 1 20  ? -36.56431 17.18106  -41.24409 1.000 50.60494  ? 20  VAL B HG11 1 
ATOM   4888 H HG12 . VAL B 1 20  ? -35.35750 16.71100  -42.16396 1.000 50.60494  ? 20  VAL B HG12 1 
ATOM   4889 H HG13 . VAL B 1 20  ? -36.53952 15.70412  -41.82850 1.000 50.60494  ? 20  VAL B HG13 1 
ATOM   4890 H HG21 . VAL B 1 20  ? -33.44555 16.30880  -41.17174 1.000 47.82837  ? 20  VAL B HG21 1 
ATOM   4891 H HG22 . VAL B 1 20  ? -33.76618 17.35765  -40.02257 1.000 47.82837  ? 20  VAL B HG22 1 
ATOM   4892 H HG23 . VAL B 1 20  ? -33.28679 15.89032  -39.64754 1.000 47.82837  ? 20  VAL B HG23 1 
ATOM   4893 N N    . ILE B 1 21  ? -38.33814 16.82674  -39.03848 1.000 51.95853  ? 21  ILE B N    1 
ATOM   4894 C CA   . ILE B 1 21  ? -39.75365 16.48442  -39.01703 1.000 47.66131  ? 21  ILE B CA   1 
ATOM   4895 C C    . ILE B 1 21  ? -40.36353 16.92421  -40.33964 1.000 57.01689  ? 21  ILE B C    1 
ATOM   4896 O O    . ILE B 1 21  ? -40.13901 18.05479  -40.78789 1.000 50.26558  ? 21  ILE B O    1 
ATOM   4897 C CB   . ILE B 1 21  ? -40.47943 17.14353  -37.82955 1.000 46.60177  ? 21  ILE B CB   1 
ATOM   4898 C CG1  . ILE B 1 21  ? -40.01035 16.53077  -36.50814 1.000 48.16634  ? 21  ILE B CG1  1 
ATOM   4899 C CG2  . ILE B 1 21  ? -41.98606 17.00802  -37.97988 1.000 51.42096  ? 21  ILE B CG2  1 
ATOM   4900 C CD1  . ILE B 1 21  ? -40.55793 17.23485  -35.28127 1.000 53.36283  ? 21  ILE B CD1  1 
ATOM   4901 H H    . ILE B 1 21  ? -38.19453 17.66897  -39.13654 1.000 62.34401  ? 21  ILE B H    1 
ATOM   4902 H HA   . ILE B 1 21  ? -39.85425 15.52302  -38.93651 1.000 57.18735  ? 21  ILE B HA   1 
ATOM   4903 N N    . CYS B 1 22  ? -41.11130 16.02197  -40.97174 1.000 61.83087  ? 22  CYS B N    1 
ATOM   4904 C CA   . CYS B 1 22  ? -41.85532 16.32505  -42.19444 1.000 57.11133  ? 22  CYS B CA   1 
ATOM   4905 C C    . CYS B 1 22  ? -43.23018 15.68573  -42.02923 1.000 60.00641  ? 22  CYS B C    1 
ATOM   4906 O O    . CYS B 1 22  ? -43.37370 14.46828  -42.17683 1.000 64.30098  ? 22  CYS B O    1 
ATOM   4907 C CB   . CYS B 1 22  ? -41.14066 15.80453  -43.43390 1.000 62.66357  ? 22  CYS B CB   1 
ATOM   4908 S SG   . CYS B 1 22  ? -42.01561 16.13555  -44.97805 1.000 62.34104  ? 22  CYS B SG   1 
ATOM   4909 H H    . CYS B 1 22  ? -41.20618 15.20935  -40.70672 1.000 74.19082  ? 22  CYS B H    1 
ATOM   4910 H HA   . CYS B 1 22  ? -41.95388 17.28485  -42.29427 1.000 68.52736  ? 22  CYS B HA   1 
ATOM   4911 H HB2  . CYS B 1 22  ? -40.26972 16.22771  -43.49134 1.000 75.19005  ? 22  CYS B HB2  1 
ATOM   4912 H HB3  . CYS B 1 22  ? -41.03781 14.84341  -43.35287 1.000 75.19005  ? 22  CYS B HB3  1 
ATOM   4913 H HG   . CYS B 1 22  ? -41.37278 15.69925  -45.89260 1.000 74.80302  ? 22  CYS B HG   1 
ATOM   4914 N N    . GLY B 1 23  ? -44.22795 16.50256  -41.70973 1.000 65.18394  ? 23  GLY B N    1 
ATOM   4915 C CA   . GLY B 1 23  ? -45.55026 15.96153  -41.43959 1.000 58.37712  ? 23  GLY B CA   1 
ATOM   4916 C C    . GLY B 1 23  ? -45.53705 15.15619  -40.15659 1.000 60.28094  ? 23  GLY B C    1 
ATOM   4917 O O    . GLY B 1 23  ? -45.07286 15.62129  -39.10970 1.000 57.92628  ? 23  GLY B O    1 
ATOM   4918 H H    . GLY B 1 23  ? -44.16643 17.35783  -41.64392 1.000 78.21450  ? 23  GLY B H    1 
ATOM   4919 H HA2  . GLY B 1 23  ? -46.19022 16.68490  -41.34968 1.000 70.04631  ? 23  GLY B HA2  1 
ATOM   4920 H HA3  . GLY B 1 23  ? -45.82580 15.38499  -42.16938 1.000 70.04631  ? 23  GLY B HA3  1 
ATOM   4921 N N    . THR B 1 24  ? -46.05094 13.92770  -40.23235 1.000 64.90858  ? 24  THR B N    1 
ATOM   4922 C CA   . THR B 1 24  ? -46.06784 13.05334  -39.06629 1.000 56.99799  ? 24  THR B CA   1 
ATOM   4923 C C    . THR B 1 24  ? -44.72088 12.37476  -38.84350 1.000 64.96456  ? 24  THR B C    1 
ATOM   4924 O O    . THR B 1 24  ? -44.38677 12.02623  -37.70508 1.000 62.53739  ? 24  THR B O    1 
ATOM   4925 C CB   . THR B 1 24  ? -47.16368 11.99541  -39.22562 1.000 59.98366  ? 24  THR B CB   1 
ATOM   4926 O OG1  . THR B 1 24  ? -47.48480 11.43378  -37.94744 1.000 76.26583  ? 24  THR B OG1  1 
ATOM   4927 C CG2  . THR B 1 24  ? -46.70851 10.88062  -40.16277 1.000 72.05846  ? 24  THR B CG2  1 
ATOM   4928 H H    . THR B 1 24  ? -46.39242 13.58173  -40.94179 1.000 77.88407  ? 24  THR B H    1 
ATOM   4929 H HA   . THR B 1 24  ? -46.27041 13.58353  -38.27967 1.000 68.39136  ? 24  THR B HA   1 
ATOM   4930 H HB   . THR B 1 24  ? -47.95366 12.41095  -39.60531 1.000 71.97417  ? 24  THR B HB   1 
ATOM   4931 H HG1  . THR B 1 24  ? -47.98053 11.95942  -37.51902 1.000 91.51277  ? 24  THR B HG1  1 
ATOM   4932 H HG21 . THR B 1 24  ? -46.22319 11.25618  -40.91398 1.000 86.46393  ? 24  THR B HG21 1 
ATOM   4933 H HG22 . THR B 1 24  ? -46.12765 10.26518  -39.68871 1.000 86.46393  ? 24  THR B HG22 1 
ATOM   4934 H HG23 . THR B 1 24  ? -47.47780 10.39333  -40.49691 1.000 86.46393  ? 24  THR B HG23 1 
ATOM   4935 N N    . THR B 1 25  ? -43.93863 12.19285  -39.90471 1.000 65.08237  ? 25  THR B N    1 
ATOM   4936 C CA   . THR B 1 25  ? -42.71528 11.40660  -39.83398 1.000 61.04920  ? 25  THR B CA   1 
ATOM   4937 C C    . THR B 1 25  ? -41.58901 12.19574  -39.17947 1.000 62.40295  ? 25  THR B C    1 
ATOM   4938 O O    . THR B 1 25  ? -41.41236 13.38999  -39.43942 1.000 63.04404  ? 25  THR B O    1 
ATOM   4939 C CB   . THR B 1 25  ? -42.28969 10.97343  -41.23768 1.000 64.11494  ? 25  THR B CB   1 
ATOM   4940 O OG1  . THR B 1 25  ? -43.41556 10.42317  -41.93506 1.000 67.96155  ? 25  THR B OG1  1 
ATOM   4941 C CG2  . THR B 1 25  ? -41.17898 9.93610   -41.16521 1.000 61.22340  ? 25  THR B CG2  1 
ATOM   4942 H H    . THR B 1 25  ? -44.09770 12.51856  -40.68459 1.000 78.09261  ? 25  THR B H    1 
ATOM   4943 H HA   . THR B 1 25  ? -42.87790 10.61673  -39.29495 1.000 73.25281  ? 25  THR B HA   1 
ATOM   4944 H HB   . THR B 1 25  ? -41.95487 11.74236  -41.72506 1.000 76.93170  ? 25  THR B HB   1 
ATOM   4945 H HG1  . THR B 1 25  ? -43.29840 10.48587  -42.76448 1.000 81.54763  ? 25  THR B HG1  1 
ATOM   4946 H HG21 . THR B 1 25  ? -40.33217 10.36945  -40.97539 1.000 73.46185  ? 25  THR B HG21 1 
ATOM   4947 H HG22 . THR B 1 25  ? -41.36905 9.29506   -40.46247 1.000 73.46185  ? 25  THR B HG22 1 
ATOM   4948 H HG23 . THR B 1 25  ? -41.10914 9.46522   -42.01037 1.000 73.46185  ? 25  THR B HG23 1 
ATOM   4949 N N    . THR B 1 26  ? -40.81541 11.51587  -38.33432 1.000 53.41969  ? 26  THR B N    1 
ATOM   4950 C CA   . THR B 1 26  ? -39.67294 12.12078  -37.66572 1.000 58.95248  ? 26  THR B CA   1 
ATOM   4951 C C    . THR B 1 26  ? -38.47898 11.18154  -37.74294 1.000 53.32439  ? 26  THR B C    1 
ATOM   4952 O O    . THR B 1 26  ? -38.61920 9.96904   -37.55740 1.000 48.15168  ? 26  THR B O    1 
ATOM   4953 C CB   . THR B 1 26  ? -39.97483 12.43960  -36.19660 1.000 53.72643  ? 26  THR B CB   1 
ATOM   4954 O OG1  . THR B 1 26  ? -41.21594 13.14865  -36.10058 1.000 76.88306  ? 26  THR B OG1  1 
ATOM   4955 C CG2  . THR B 1 26  ? -38.85693 13.29013  -35.60482 1.000 54.51036  ? 26  THR B CG2  1 
ATOM   4956 H H    . THR B 1 26  ? -40.93724 10.68916  -38.13106 1.000 64.09740  ? 26  THR B H    1 
ATOM   4957 H HA   . THR B 1 26  ? -39.44727 12.94930  -38.11686 1.000 70.73674  ? 26  THR B HA   1 
ATOM   4958 H HB   . THR B 1 26  ? -40.03940 11.61523  -35.68950 1.000 64.46549  ? 26  THR B HB   1 
ATOM   4959 H HG1  . THR B 1 26  ? -41.84574 12.60880  -35.96820 1.000 92.25344  ? 26  THR B HG1  1 
ATOM   4960 H HG21 . THR B 1 26  ? -38.61929 14.00085  -36.22070 1.000 65.40620  ? 26  THR B HG21 1 
ATOM   4961 H HG22 . THR B 1 26  ? -38.07419 12.74137  -35.44025 1.000 65.40620  ? 26  THR B HG22 1 
ATOM   4962 H HG23 . THR B 1 26  ? -39.14736 13.68354  -34.76710 1.000 65.40620  ? 26  THR B HG23 1 
ATOM   4963 N N    . LEU B 1 27  ? -37.30393 11.74281  -38.00776 1.000 50.67172  ? 27  LEU B N    1 
ATOM   4964 C CA   . LEU B 1 27  ? -36.08339 10.95039  -38.07459 1.000 46.36353  ? 27  LEU B CA   1 
ATOM   4965 C C    . LEU B 1 27  ? -34.89145 11.88139  -37.89024 1.000 47.45715  ? 27  LEU B C    1 
ATOM   4966 O O    . LEU B 1 27  ? -35.04428 13.08455  -37.66229 1.000 48.90520  ? 27  LEU B O    1 
ATOM   4967 C CB   . LEU B 1 27  ? -36.01505 10.16491  -39.38793 1.000 43.65727  ? 27  LEU B CB   1 
ATOM   4968 C CG   . LEU B 1 27  ? -36.23786 10.93331  -40.69116 1.000 45.65508  ? 27  LEU B CG   1 
ATOM   4969 C CD1  . LEU B 1 27  ? -35.00714 11.73657  -41.07327 1.000 50.41037  ? 27  LEU B CD1  1 
ATOM   4970 C CD2  . LEU B 1 27  ? -36.63498 9.97258   -41.81332 1.000 47.77036  ? 27  LEU B CD2  1 
ATOM   4971 H H    . LEU B 1 27  ? -37.18827 12.58260  -38.15261 1.000 60.79984  ? 27  LEU B H    1 
ATOM   4972 H HA   . LEU B 1 27  ? -36.07135 10.31375  -37.34284 1.000 55.63000  ? 27  LEU B HA   1 
ATOM   4973 H HB2  . LEU B 1 27  ? -35.13354 9.76446   -39.44694 1.000 52.38249  ? 27  LEU B HB2  1 
ATOM   4974 H HB3  . LEU B 1 27  ? -36.69267 9.47172   -39.35299 1.000 52.38249  ? 27  LEU B HB3  1 
ATOM   4975 H HG   . LEU B 1 27  ? -36.96346 11.56394  -40.56193 1.000 54.77987  ? 27  LEU B HG   1 
ATOM   4976 H HD11 . LEU B 1 27  ? -34.95204 12.51998  -40.50395 1.000 60.48621  ? 27  LEU B HD11 1 
ATOM   4977 H HD12 . LEU B 1 27  ? -34.21923 11.18383  -40.95251 1.000 60.48621  ? 27  LEU B HD12 1 
ATOM   4978 H HD13 . LEU B 1 27  ? -35.08230 12.00705  -42.00176 1.000 60.48621  ? 27  LEU B HD13 1 
ATOM   4979 H HD21 . LEU B 1 27  ? -36.04395 10.10948  -42.57018 1.000 57.31821  ? 27  LEU B HD21 1 
ATOM   4980 H HD22 . LEU B 1 27  ? -36.55484 9.06096   -41.49170 1.000 57.31821  ? 27  LEU B HD22 1 
ATOM   4981 H HD23 . LEU B 1 27  ? -37.55212 10.15226  -42.07308 1.000 57.31821  ? 27  LEU B HD23 1 
ATOM   4982 N N    . ASN B 1 28  ? -33.69687 11.31159  -37.98462 1.000 49.20967  ? 28  ASN B N    1 
ATOM   4983 C CA   . ASN B 1 28  ? -32.48101 12.04241  -37.66986 1.000 44.70425  ? 28  ASN B CA   1 
ATOM   4984 C C    . ASN B 1 28  ? -31.86573 12.65688  -38.92126 1.000 41.75928  ? 28  ASN B C    1 
ATOM   4985 O O    . ASN B 1 28  ? -31.99989 12.13274  -40.03069 1.000 36.14998  ? 28  ASN B O    1 
ATOM   4986 C CB   . ASN B 1 28  ? -31.46896 11.12310  -36.98330 1.000 42.43350  ? 28  ASN B CB   1 
ATOM   4987 C CG   . ASN B 1 28  ? -32.02582 10.48782  -35.72343 1.000 42.63873  ? 28  ASN B CG   1 
ATOM   4988 O OD1  . ASN B 1 28  ? -32.07417 11.11525  -34.66335 1.000 41.49659  ? 28  ASN B OD1  1 
ATOM   4989 N ND2  . ASN B 1 28  ? -32.45408 9.23661   -35.83452 1.000 38.98726  ? 28  ASN B ND2  1 
ATOM   4990 H H    . ASN B 1 28  ? -33.56528 10.49802  -38.23034 1.000 59.04538  ? 28  ASN B H    1 
ATOM   4991 H HA   . ASN B 1 28  ? -32.69557 12.76932  -37.06449 1.000 53.63887  ? 28  ASN B HA   1 
ATOM   4992 H HB2  . ASN B 1 28  ? -31.22021 10.41224  -37.59461 1.000 50.91397  ? 28  ASN B HB2  1 
ATOM   4993 H HB3  . ASN B 1 28  ? -30.68532 11.64000  -36.73910 1.000 50.91397  ? 28  ASN B HB3  1 
ATOM   4994 H HD21 . ASN B 1 28  ? -32.77892 8.83087   -35.14936 1.000 46.77848  ? 28  ASN B HD21 1 
ATOM   4995 H HD22 . ASN B 1 28  ? -32.40675 8.83155   -36.59168 1.000 46.77848  ? 28  ASN B HD22 1 
ATOM   4996 N N    . GLY B 1 29  ? -31.20464 13.79853  -38.72220 1.000 35.27008  ? 29  GLY B N    1 
ATOM   4997 C CA   . GLY B 1 29  ? -30.45759 14.44359  -39.77815 1.000 35.51354  ? 29  GLY B CA   1 
ATOM   4998 C C    . GLY B 1 29  ? -29.05160 14.74709  -39.31441 1.000 37.04679  ? 29  GLY B C    1 
ATOM   4999 O O    . GLY B 1 29  ? -28.73580 14.71194  -38.12095 1.000 36.83160  ? 29  GLY B O    1 
ATOM   5000 H H    . GLY B 1 29  ? -31.17845 14.21770  -37.97172 1.000 42.31786  ? 29  GLY B H    1 
ATOM   5001 H HA2  . GLY B 1 29  ? -30.41424 13.86256  -40.55367 1.000 42.61002  ? 29  GLY B HA2  1 
ATOM   5002 H HA3  . GLY B 1 29  ? -30.89179 15.27379  -40.02943 1.000 42.61002  ? 29  GLY B HA3  1 
ATOM   5003 N N    . LEU B 1 30  ? -28.18971 15.04282  -40.29083 1.000 34.10349  ? 30  LEU B N    1 
ATOM   5004 C CA   . LEU B 1 30  ? -26.79432 15.39419  -40.05496 1.000 37.13268  ? 30  LEU B CA   1 
ATOM   5005 C C    . LEU B 1 30  ? -26.55785 16.81804  -40.54241 1.000 37.35265  ? 30  LEU B C    1 
ATOM   5006 O O    . LEU B 1 30  ? -26.65860 17.09268  -41.74320 1.000 30.96407  ? 30  LEU B O    1 
ATOM   5007 C CB   . LEU B 1 30  ? -25.85764 14.41623  -40.76544 1.000 34.84752  ? 30  LEU B CB   1 
ATOM   5008 C CG   . LEU B 1 30  ? -24.36412 14.65478  -40.54751 1.000 35.54479  ? 30  LEU B CG   1 
ATOM   5009 C CD1  . LEU B 1 30  ? -23.93345 14.15257  -39.17823 1.000 45.45443  ? 30  LEU B CD1  1 
ATOM   5010 C CD2  . LEU B 1 30  ? -23.56295 13.99210  -41.64457 1.000 35.51783  ? 30  LEU B CD2  1 
ATOM   5011 H H    . LEU B 1 30  ? -28.40087 15.04562  -41.12450 1.000 40.91796  ? 30  LEU B H    1 
ATOM   5012 H HA   . LEU B 1 30  ? -26.60652 15.36277  -39.10384 1.000 44.55299  ? 30  LEU B HA   1 
ATOM   5013 H HB2  . LEU B 1 30  ? -26.05628 13.52104  -40.44910 1.000 41.81080  ? 30  LEU B HB2  1 
ATOM   5014 H HB3  . LEU B 1 30  ? -26.02336 14.47540  -41.71935 1.000 41.81080  ? 30  LEU B HB3  1 
ATOM   5015 H HG   . LEU B 1 30  ? -24.18506 15.60759  -40.57890 1.000 42.64752  ? 30  LEU B HG   1 
ATOM   5016 H HD11 . LEU B 1 30  ? -24.14894 13.20960  -39.10558 1.000 54.53909  ? 30  LEU B HD11 1 
ATOM   5017 H HD12 . LEU B 1 30  ? -22.97702 14.28176  -39.08094 1.000 54.53909  ? 30  LEU B HD12 1 
ATOM   5018 H HD13 . LEU B 1 30  ? -24.40607 14.65347  -38.49514 1.000 54.53909  ? 30  LEU B HD13 1 
ATOM   5019 H HD21 . LEU B 1 30  ? -22.61814 14.12646  -41.47085 1.000 42.61517  ? 30  LEU B HD21 1 
ATOM   5020 H HD22 . LEU B 1 30  ? -23.76577 13.04360  -41.65484 1.000 42.61517  ? 30  LEU B HD22 1 
ATOM   5021 H HD23 . LEU B 1 30  ? -23.80276 14.39087  -42.49567 1.000 42.61517  ? 30  LEU B HD23 1 
ATOM   5022 N N    . TRP B 1 31  ? -26.22602 17.71170  -39.61275 1.000 35.61546  ? 31  TRP B N    1 
ATOM   5023 C CA   . TRP B 1 31  ? -26.13232 19.14513  -39.87189 1.000 36.69064  ? 31  TRP B CA   1 
ATOM   5024 C C    . TRP B 1 31  ? -24.66651 19.52238  -40.05700 1.000 39.18938  ? 31  TRP B C    1 
ATOM   5025 O O    . TRP B 1 31  ? -23.89761 19.55000  -39.09046 1.000 34.23616  ? 31  TRP B O    1 
ATOM   5026 C CB   . TRP B 1 31  ? -26.76370 19.92459  -38.71926 1.000 45.42590  ? 31  TRP B CB   1 
ATOM   5027 C CG   . TRP B 1 31  ? -26.81040 21.41327  -38.90728 1.000 42.99147  ? 31  TRP B CG   1 
ATOM   5028 C CD1  . TRP B 1 31  ? -26.75319 22.10186  -40.08553 1.000 46.93849  ? 31  TRP B CD1  1 
ATOM   5029 C CD2  . TRP B 1 31  ? -26.92793 22.39582  -37.87438 1.000 42.56011  ? 31  TRP B CD2  1 
ATOM   5030 N NE1  . TRP B 1 31  ? -26.82685 23.45335  -39.84741 1.000 44.59688  ? 31  TRP B NE1  1 
ATOM   5031 C CE2  . TRP B 1 31  ? -26.93652 23.65917  -38.49726 1.000 42.24796  ? 31  TRP B CE2  1 
ATOM   5032 C CE3  . TRP B 1 31  ? -27.02738 22.32919  -36.48190 1.000 44.23574  ? 31  TRP B CE3  1 
ATOM   5033 C CZ2  . TRP B 1 31  ? -27.03577 24.84421  -37.77538 1.000 48.37164  ? 31  TRP B CZ2  1 
ATOM   5034 C CZ3  . TRP B 1 31  ? -27.12804 23.50629  -35.76815 1.000 53.90109  ? 31  TRP B CZ3  1 
ATOM   5035 C CH2  . TRP B 1 31  ? -27.13204 24.74708  -36.41517 1.000 48.26075  ? 31  TRP B CH2  1 
ATOM   5036 H H    . TRP B 1 31  ? -26.04487 17.50406  -38.79809 1.000 42.73232  ? 31  TRP B H    1 
ATOM   5037 H HA   . TRP B 1 31  ? -26.59941 19.36060  -40.69426 1.000 44.02254  ? 31  TRP B HA   1 
ATOM   5038 H HB2  . TRP B 1 31  ? -27.67678 19.61768  -38.60527 1.000 54.50486  ? 31  TRP B HB2  1 
ATOM   5039 H HB3  . TRP B 1 31  ? -26.25193 19.74967  -37.91404 1.000 54.50486  ? 31  TRP B HB3  1 
ATOM   5040 H HD1  . TRP B 1 31  ? -26.67566 21.71270  -40.92662 1.000 56.31996  ? 31  TRP B HD1  1 
ATOM   5041 H HE1  . TRP B 1 31  ? -26.80731 24.06903  -40.44753 1.000 53.51002  ? 31  TRP B HE1  1 
ATOM   5042 H HE3  . TRP B 1 31  ? -27.02576 21.50821  -36.04500 1.000 53.07666  ? 31  TRP B HE3  1 
ATOM   5043 H HZ2  . TRP B 1 31  ? -27.03661 25.67073  -38.20173 1.000 58.03975  ? 31  TRP B HZ2  1 
ATOM   5044 H HZ3  . TRP B 1 31  ? -27.19437 23.47423  -34.84107 1.000 64.67507  ? 31  TRP B HZ3  1 
ATOM   5045 H HH2  . TRP B 1 31  ? -27.20180 25.52356  -35.90811 1.000 57.90667  ? 31  TRP B HH2  1 
ATOM   5046 N N    . LEU B 1 32  ? -24.28461 19.80964  -41.30022 1.000 32.97125  ? 32  LEU B N    1 
ATOM   5047 C CA   . LEU B 1 32  ? -22.92623 20.20350  -41.64867 1.000 37.37541  ? 32  LEU B CA   1 
ATOM   5048 C C    . LEU B 1 32  ? -22.99102 21.48710  -42.46117 1.000 44.18168  ? 32  LEU B C    1 
ATOM   5049 O O    . LEU B 1 32  ? -23.73649 21.56357  -43.44440 1.000 38.93856  ? 32  LEU B O    1 
ATOM   5050 C CB   . LEU B 1 32  ? -22.21359 19.10577  -42.44580 1.000 44.45095  ? 32  LEU B CB   1 
ATOM   5051 C CG   . LEU B 1 32  ? -22.10945 17.72618  -41.78973 1.000 38.80124  ? 32  LEU B CG   1 
ATOM   5052 C CD1  . LEU B 1 32  ? -21.43518 16.75395  -42.75032 1.000 34.92679  ? 32  LEU B CD1  1 
ATOM   5053 C CD2  . LEU B 1 32  ? -21.35492 17.77861  -40.46469 1.000 36.55802  ? 32  LEU B CD2  1 
ATOM   5054 H H    . LEU B 1 32  ? -24.81290 19.78186  -41.97826 1.000 39.55927  ? 32  LEU B H    1 
ATOM   5055 H HA   . LEU B 1 32  ? -22.41344 20.36839  -40.84198 1.000 44.84426  ? 32  LEU B HA   1 
ATOM   5056 H HB2  . LEU B 1 32  ? -22.69108 18.98616  -43.28162 1.000 53.33491  ? 32  LEU B HB2  1 
ATOM   5057 H HB3  . LEU B 1 32  ? -21.30761 19.40469  -42.62114 1.000 53.33491  ? 32  LEU B HB3  1 
ATOM   5058 H HG   . LEU B 1 32  ? -23.00432 17.41019  -41.58911 1.000 46.55526  ? 32  LEU B HG   1 
ATOM   5059 H HD11 . LEU B 1 32  ? -21.39682 15.87722  -42.33707 1.000 41.90592  ? 32  LEU B HD11 1 
ATOM   5060 H HD12 . LEU B 1 32  ? -21.95165 16.71085  -43.57026 1.000 41.90592  ? 32  LEU B HD12 1 
ATOM   5061 H HD13 . LEU B 1 32  ? -20.53789 17.06940  -42.94079 1.000 41.90592  ? 32  LEU B HD13 1 
ATOM   5062 H HD21 . LEU B 1 32  ? -21.44530 16.92350  -40.01577 1.000 43.86339  ? 32  LEU B HD21 1 
ATOM   5063 H HD22 . LEU B 1 32  ? -20.41897 17.96220  -40.64129 1.000 43.86339  ? 32  LEU B HD22 1 
ATOM   5064 H HD23 . LEU B 1 32  ? -21.73197 18.48267  -39.91421 1.000 43.86339  ? 32  LEU B HD23 1 
ATOM   5065 N N    . ASP B 1 33  ? -22.20684 22.48735  -42.05519 1.000 44.98573  ? 33  ASP B N    1 
ATOM   5066 C CA   . ASP B 1 33  ? -22.31814 23.81546  -42.64828 1.000 46.86100  ? 33  ASP B CA   1 
ATOM   5067 C C    . ASP B 1 33  ? -23.79247 24.21172  -42.68667 1.000 49.95757  ? 33  ASP B C    1 
ATOM   5068 O O    . ASP B 1 33  ? -24.52099 23.97415  -41.71716 1.000 43.94507  ? 33  ASP B O    1 
ATOM   5069 C CB   . ASP B 1 33  ? -21.68253 23.83477  -44.04041 1.000 43.02692  ? 33  ASP B CB   1 
ATOM   5070 C CG   . ASP B 1 33  ? -20.20584 23.46915  -44.01491 1.000 48.43227  ? 33  ASP B CG   1 
ATOM   5071 O OD1  . ASP B 1 33  ? -19.50990 23.84276  -43.04692 1.000 48.20237  ? 33  ASP B OD1  1 
ATOM   5072 O OD2  . ASP B 1 33  ? -19.73710 22.80680  -44.96429 1.000 45.12382  ? 33  ASP B OD2  1 
ATOM   5073 H H    . ASP B 1 33  ? -21.60751 22.42042  -41.44207 1.000 53.97665  ? 33  ASP B H    1 
ATOM   5074 H HA   . ASP B 1 33  ? -21.83743 24.47304  -42.12158 1.000 56.22697  ? 33  ASP B HA   1 
ATOM   5075 H HB2  . ASP B 1 33  ? -22.14091 23.19431  -44.60663 1.000 51.62608  ? 33  ASP B HB2  1 
ATOM   5076 H HB3  . ASP B 1 33  ? -21.76494 24.72625  -44.41372 1.000 51.62608  ? 33  ASP B HB3  1 
ATOM   5077 N N    . ASP B 1 34  ? -24.25213 24.79636  -43.79189 1.000 45.00782  ? 34  ASP B N    1 
ATOM   5078 C CA   . ASP B 1 34  ? -25.64032 25.23904  -43.92335 1.000 47.31101  ? 34  ASP B CA   1 
ATOM   5079 C C    . ASP B 1 34  ? -26.50109 24.19828  -44.62756 1.000 49.49752  ? 34  ASP B C    1 
ATOM   5080 O O    . ASP B 1 34  ? -27.41729 24.54189  -45.38027 1.000 48.36466  ? 34  ASP B O    1 
ATOM   5081 C CB   . ASP B 1 34  ? -25.70719 26.57853  -44.65586 1.000 52.57846  ? 34  ASP B CB   1 
ATOM   5082 C CG   . ASP B 1 34  ? -25.19602 26.49973  -46.08696 1.000 55.10407  ? 34  ASP B CG   1 
ATOM   5083 O OD1  . ASP B 1 34  ? -24.65647 25.44580  -46.48387 1.000 55.08070  ? 34  ASP B OD1  1 
ATOM   5084 O OD2  . ASP B 1 34  ? -25.33760 27.50148  -46.82003 1.000 64.52744  ? 34  ASP B OD2  1 
ATOM   5085 H H    . ASP B 1 34  ? -23.77220 24.94964  -44.48886 1.000 54.00316  ? 34  ASP B H    1 
ATOM   5086 H HA   . ASP B 1 34  ? -26.00528 25.37233  -43.03456 1.000 56.76698  ? 34  ASP B HA   1 
ATOM   5087 H HB2  . ASP B 1 34  ? -26.62982 26.87665  -44.68400 1.000 63.08792  ? 34  ASP B HB2  1 
ATOM   5088 H HB3  . ASP B 1 34  ? -25.16382 27.22568  -44.17958 1.000 63.08792  ? 34  ASP B HB3  1 
ATOM   5089 N N    . VAL B 1 35  ? -26.22953 22.91487  -44.39402 1.000 49.29383  ? 35  VAL B N    1 
ATOM   5090 C CA   . VAL B 1 35  ? -26.98810 21.82865  -44.99720 1.000 50.61234  ? 35  VAL B CA   1 
ATOM   5091 C C    . VAL B 1 35  ? -27.30859 20.78932  -43.93385 1.000 45.18159  ? 35  VAL B C    1 
ATOM   5092 O O    . VAL B 1 35  ? -26.52142 20.54573  -43.01353 1.000 40.56946  ? 35  VAL B O    1 
ATOM   5093 C CB   . VAL B 1 35  ? -26.22789 21.16400  -46.16661 1.000 47.27969  ? 35  VAL B CB   1 
ATOM   5094 C CG1  . VAL B 1 35  ? -26.99745 19.94984  -46.67554 1.000 45.42200  ? 35  VAL B CG1  1 
ATOM   5095 C CG2  . VAL B 1 35  ? -25.98773 22.15984  -47.28194 1.000 41.43299  ? 35  VAL B CG2  1 
ATOM   5096 H H    . VAL B 1 35  ? -25.59624 22.64592  -43.87806 1.000 59.14636  ? 35  VAL B H    1 
ATOM   5097 H HA   . VAL B 1 35  ? -27.82175 22.19121  -45.33553 1.000 60.72857  ? 35  VAL B HA   1 
ATOM   5098 H HB   . VAL B 1 35  ? -25.36259 20.86115  -45.84968 1.000 56.72940  ? 35  VAL B HB   1 
ATOM   5099 H HG11 . VAL B 1 35  ? -26.62702 19.67627  -47.52927 1.000 54.50017  ? 35  VAL B HG11 1 
ATOM   5100 H HG12 . VAL B 1 35  ? -26.91212 19.22928  -46.03179 1.000 54.50017  ? 35  VAL B HG12 1 
ATOM   5101 H HG13 . VAL B 1 35  ? -27.93132 20.18963  -46.78176 1.000 54.50017  ? 35  VAL B HG13 1 
ATOM   5102 H HG21 . VAL B 1 35  ? -26.70517 22.81266  -47.28232 1.000 49.71337  ? 35  VAL B HG21 1 
ATOM   5103 H HG22 . VAL B 1 35  ? -25.13772 22.60258  -47.13239 1.000 49.71337  ? 35  VAL B HG22 1 
ATOM   5104 H HG23 . VAL B 1 35  ? -25.97006 21.68728  -48.12886 1.000 49.71337  ? 35  VAL B HG23 1 
ATOM   5105 N N    . VAL B 1 36  ? -28.47933 20.17337  -44.07181 1.000 34.21366  ? 36  VAL B N    1 
ATOM   5106 C CA   . VAL B 1 36  ? -28.88780 19.03379  -43.26013 1.000 42.83410  ? 36  VAL B CA   1 
ATOM   5107 C C    . VAL B 1 36  ? -29.16332 17.87282  -44.20501 1.000 35.78689  ? 36  VAL B C    1 
ATOM   5108 O O    . VAL B 1 36  ? -29.87290 18.03689  -45.20454 1.000 42.20151  ? 36  VAL B O    1 
ATOM   5109 C CB   . VAL B 1 36  ? -30.12480 19.35414  -42.40016 1.000 42.85965  ? 36  VAL B CB   1 
ATOM   5110 C CG1  . VAL B 1 36  ? -30.64627 18.09869  -41.70882 1.000 42.08602  ? 36  VAL B CG1  1 
ATOM   5111 C CG2  . VAL B 1 36  ? -29.78875 20.41428  -41.36723 1.000 38.73848  ? 36  VAL B CG2  1 
ATOM   5112 H H    . VAL B 1 36  ? -29.07277 20.40658  -44.64891 1.000 41.05017  ? 36  VAL B H    1 
ATOM   5113 H HA   . VAL B 1 36  ? -28.16771 18.78442  -42.65998 1.000 51.39469  ? 36  VAL B HA   1 
ATOM   5114 H HB   . VAL B 1 36  ? -30.82374 19.69352  -42.98085 1.000 51.42535  ? 36  VAL B HB   1 
ATOM   5115 H HG11 . VAL B 1 36  ? -31.39953 18.33767  -41.14633 1.000 50.49699  ? 36  VAL B HG11 1 
ATOM   5116 H HG12 . VAL B 1 36  ? -30.92642 17.46011  -42.38308 1.000 50.49699  ? 36  VAL B HG12 1 
ATOM   5117 H HG13 . VAL B 1 36  ? -29.93680 17.71841  -41.16758 1.000 50.49699  ? 36  VAL B HG13 1 
ATOM   5118 H HG21 . VAL B 1 36  ? -30.55325 20.54010  -40.78360 1.000 46.47995  ? 36  VAL B HG21 1 
ATOM   5119 H HG22 . VAL B 1 36  ? -29.02276 20.11976  -40.85011 1.000 46.47995  ? 36  VAL B HG22 1 
ATOM   5120 H HG23 . VAL B 1 36  ? -29.58050 21.24470  -41.82323 1.000 46.47995  ? 36  VAL B HG23 1 
ATOM   5121 N N    . TYR B 1 37  ? -28.59305 16.70941  -43.89298 1.000 38.56820  ? 37  TYR B N    1 
ATOM   5122 C CA   . TYR B 1 37  ? -28.75498 15.49761  -44.68523 1.000 35.69535  ? 37  TYR B CA   1 
ATOM   5123 C C    . TYR B 1 37  ? -29.59262 14.48650  -43.91470 1.000 29.69720  ? 37  TYR B C    1 
ATOM   5124 O O    . TYR B 1 37  ? -29.37811 14.28024  -42.71665 1.000 36.16358  ? 37  TYR B O    1 
ATOM   5125 C CB   . TYR B 1 37  ? -27.40481 14.85766  -45.01986 1.000 28.90945  ? 37  TYR B CB   1 
ATOM   5126 C CG   . TYR B 1 37  ? -26.41120 15.76802  -45.69497 1.000 37.30268  ? 37  TYR B CG   1 
ATOM   5127 C CD1  . TYR B 1 37  ? -25.65070 16.66545  -44.95668 1.000 36.52794  ? 37  TYR B CD1  1 
ATOM   5128 C CD2  . TYR B 1 37  ? -26.21046 15.71063  -47.06774 1.000 39.11664  ? 37  TYR B CD2  1 
ATOM   5129 C CE1  . TYR B 1 37  ? -24.73233 17.49313  -45.56821 1.000 37.43433  ? 37  TYR B CE1  1 
ATOM   5130 C CE2  . TYR B 1 37  ? -25.29237 16.53318  -47.68823 1.000 39.38485  ? 37  TYR B CE2  1 
ATOM   5131 C CZ   . TYR B 1 37  ? -24.55538 17.42057  -46.93548 1.000 39.03912  ? 37  TYR B CZ   1 
ATOM   5132 O OH   . TYR B 1 37  ? -23.64276 18.24040  -47.55768 1.000 53.01089  ? 37  TYR B OH   1 
ATOM   5133 H H    . TYR B 1 37  ? -28.09168 16.59667  -43.20340 1.000 46.27562  ? 37  TYR B H    1 
ATOM   5134 H HA   . TYR B 1 37  ? -29.20483 15.72592  -45.51373 1.000 42.82819  ? 37  TYR B HA   1 
ATOM   5135 H HB2  . TYR B 1 37  ? -26.99989 14.54823  -44.19452 1.000 34.68511  ? 37  TYR B HB2  1 
ATOM   5136 H HB3  . TYR B 1 37  ? -27.56079 14.10737  -45.61453 1.000 34.68511  ? 37  TYR B HB3  1 
ATOM   5137 H HD1  . TYR B 1 37  ? -25.76254 16.70907  -44.03446 1.000 43.82730  ? 37  TYR B HD1  1 
ATOM   5138 H HD2  . TYR B 1 37  ? -26.70269 15.10814  -47.57726 1.000 46.93374  ? 37  TYR B HD2  1 
ATOM   5139 H HE1  . TYR B 1 37  ? -24.23582 18.09581  -45.06308 1.000 44.91497  ? 37  TYR B HE1  1 
ATOM   5140 H HE2  . TYR B 1 37  ? -25.17196 16.48860  -48.60932 1.000 47.25559  ? 37  TYR B HE2  1 
ATOM   5141 H HH   . TYR B 1 37  ? -23.33586 18.79734  -47.00883 1.000 63.60684  ? 37  TYR B HH   1 
ATOM   5142 N N    . CYS B 1 38  ? -30.52377 13.83537  -44.60584 1.000 34.68931  ? 38  CYS B N    1 
ATOM   5143 C CA   . CYS B 1 38  ? -31.39085 12.84700  -43.97751 1.000 40.61476  ? 38  CYS B CA   1 
ATOM   5144 C C    . CYS B 1 38  ? -31.88432 11.88346  -45.04738 1.000 34.76969  ? 38  CYS B C    1 
ATOM   5145 O O    . CYS B 1 38  ? -31.85203 12.20553  -46.24142 1.000 35.22431  ? 38  CYS B O    1 
ATOM   5146 C CB   . CYS B 1 38  ? -32.58063 13.51624  -43.26776 1.000 39.98156  ? 38  CYS B CB   1 
ATOM   5147 S SG   . CYS B 1 38  ? -33.77527 14.29155  -44.38346 1.000 40.66564  ? 38  CYS B SG   1 
ATOM   5148 H H    . CYS B 1 38  ? -30.67266 13.95011  -45.44505 1.000 41.62094  ? 38  CYS B H    1 
ATOM   5149 H HA   . CYS B 1 38  ? -30.88313 12.34351  -43.32205 1.000 48.73149  ? 38  CYS B HA   1 
ATOM   5150 H HB2  . CYS B 1 38  ? -33.05300 12.84266  -42.75389 1.000 47.97165  ? 38  CYS B HB2  1 
ATOM   5151 H HB3  . CYS B 1 38  ? -32.24015 14.20602  -42.67684 1.000 47.97165  ? 38  CYS B HB3  1 
ATOM   5152 H HG   . CYS B 1 38  ? -34.21191 13.45830  -45.12847 1.000 48.79255  ? 38  CYS B HG   1 
ATOM   5153 N N    . PRO B 1 39  ? -32.34771 10.69658  -44.65418 1.000 32.45206  ? 39  PRO B N    1 
ATOM   5154 C CA   . PRO B 1 39  ? -32.93086 9.77567   -45.63861 1.000 35.75894  ? 39  PRO B CA   1 
ATOM   5155 C C    . PRO B 1 39  ? -34.17083 10.38605  -46.27155 1.000 36.72942  ? 39  PRO B C    1 
ATOM   5156 O O    . PRO B 1 39  ? -34.95095 11.07830  -45.61396 1.000 37.30690  ? 39  PRO B O    1 
ATOM   5157 C CB   . PRO B 1 39  ? -33.27324 8.52853   -44.81301 1.000 35.23336  ? 39  PRO B CB   1 
ATOM   5158 C CG   . PRO B 1 39  ? -32.51522 8.67678   -43.52430 1.000 39.75105  ? 39  PRO B CG   1 
ATOM   5159 C CD   . PRO B 1 39  ? -32.38998 10.14918  -43.28812 1.000 37.70194  ? 39  PRO B CD   1 
ATOM   5160 H HA   . PRO B 1 39  ? -32.28483 9.54032   -46.32283 1.000 42.90450  ? 39  PRO B HA   1 
ATOM   5161 H HB2  . PRO B 1 39  ? -34.22878 8.49595   -44.64940 1.000 42.27381  ? 39  PRO B HB2  1 
ATOM   5162 H HB3  . PRO B 1 39  ? -32.99093 7.73228   -45.28965 1.000 42.27381  ? 39  PRO B HB3  1 
ATOM   5163 H HG2  . PRO B 1 39  ? -33.00917 8.25447   -42.80419 1.000 47.69503  ? 39  PRO B HG2  1 
ATOM   5164 H HG3  . PRO B 1 39  ? -31.64010 8.26743   -43.61097 1.000 47.69503  ? 39  PRO B HG3  1 
ATOM   5165 H HD2  . PRO B 1 39  ? -33.15720 10.48913  -42.80161 1.000 45.23609  ? 39  PRO B HD2  1 
ATOM   5166 H HD3  . PRO B 1 39  ? -31.57371 10.35519  -42.80628 1.000 45.23609  ? 39  PRO B HD3  1 
ATOM   5167 N N    . ARG B 1 40  ? -34.35758 10.11521  -47.56218 1.000 33.81918  ? 40  ARG B N    1 
ATOM   5168 C CA   . ARG B 1 40  ? -35.43513 10.77673  -48.28285 1.000 36.65141  ? 40  ARG B CA   1 
ATOM   5169 C C    . ARG B 1 40  ? -36.81352 10.22896  -47.92185 1.000 35.09300  ? 40  ARG B C    1 
ATOM   5170 O O    . ARG B 1 40  ? -37.81172 10.91004  -48.16878 1.000 37.00429  ? 40  ARG B O    1 
ATOM   5171 C CB   . ARG B 1 40  ? -35.20320 10.67152  -49.79029 1.000 33.95915  ? 40  ARG B CB   1 
ATOM   5172 C CG   . ARG B 1 40  ? -35.53962 9.32870   -50.39386 1.000 34.25444  ? 40  ARG B CG   1 
ATOM   5173 C CD   . ARG B 1 40  ? -35.16216 9.31455   -51.85856 1.000 36.57982  ? 40  ARG B CD   1 
ATOM   5174 N NE   . ARG B 1 40  ? -35.22596 7.98160   -52.44050 1.000 31.19131  ? 40  ARG B NE   1 
ATOM   5175 C CZ   . ARG B 1 40  ? -35.12731 7.73467   -53.73876 1.000 33.85457  ? 40  ARG B CZ   1 
ATOM   5176 N NH1  . ARG B 1 40  ? -34.94009 8.70897   -54.61422 1.000 38.10356  ? 40  ARG B NH1  1 
ATOM   5177 N NH2  . ARG B 1 40  ? -35.23432 6.48185   -54.17117 1.000 35.73827  ? 40  ARG B NH2  1 
ATOM   5178 H H    . ARG B 1 40  ? -33.88620 9.56743   -48.02837 1.000 40.57679  ? 40  ARG B H    1 
ATOM   5179 H HA   . ARG B 1 40  ? -35.42801 11.71731  -48.04583 1.000 43.97546  ? 40  ARG B HA   1 
ATOM   5180 H HB2  . ARG B 1 40  ? -35.75405 11.33594  -50.23302 1.000 40.74475  ? 40  ARG B HB2  1 
ATOM   5181 H HB3  . ARG B 1 40  ? -34.26581 10.84475  -49.96975 1.000 40.74475  ? 40  ARG B HB3  1 
ATOM   5182 H HG2  . ARG B 1 40  ? -35.04385 8.63099   -49.93744 1.000 41.09910  ? 40  ARG B HG2  1 
ATOM   5183 H HG3  . ARG B 1 40  ? -36.49235 9.16398   -50.31587 1.000 41.09910  ? 40  ARG B HG3  1 
ATOM   5184 H HD2  . ARG B 1 40  ? -35.77380 9.88588   -52.34886 1.000 43.88956  ? 40  ARG B HD2  1 
ATOM   5185 H HD3  . ARG B 1 40  ? -34.25386 9.64110   -51.95480 1.000 43.88956  ? 40  ARG B HD3  1 
ATOM   5186 H HE   . ARG B 1 40  ? -35.33424 7.31385   -51.90947 1.000 37.42334  ? 40  ARG B HE   1 
ATOM   5187 H HH11 . ARG B 1 40  ? -34.87981 9.52344   -54.34479 1.000 45.71804  ? 40  ARG B HH11 1 
ATOM   5188 H HH12 . ARG B 1 40  ? -34.87869 8.52775   -55.45266 1.000 45.71804  ? 40  ARG B HH12 1 
ATOM   5189 H HH21 . ARG B 1 40  ? -35.36598 5.84320   -53.61047 1.000 42.87970  ? 40  ARG B HH21 1 
ATOM   5190 H HH22 . ARG B 1 40  ? -35.17188 6.31021   -55.01155 1.000 42.87970  ? 40  ARG B HH22 1 
ATOM   5191 N N    . HIS B 1 41  ? -36.90042 9.03740   -47.32819 1.000 35.18489  ? 41  HIS B N    1 
ATOM   5192 C CA   . HIS B 1 41  ? -38.22323 8.51787   -46.98091 1.000 43.63475  ? 41  HIS B CA   1 
ATOM   5193 C C    . HIS B 1 41  ? -38.81960 9.21623   -45.75853 1.000 41.93527  ? 41  HIS B C    1 
ATOM   5194 O O    . HIS B 1 41  ? -39.83527 8.74947   -45.23232 1.000 41.90666  ? 41  HIS B O    1 
ATOM   5195 C CB   . HIS B 1 41  ? -38.17697 6.99586   -46.78221 1.000 37.84088  ? 41  HIS B CB   1 
ATOM   5196 C CG   . HIS B 1 41  ? -37.43500 6.53935   -45.56313 1.000 47.78461  ? 41  HIS B CG   1 
ATOM   5197 N ND1  . HIS B 1 41  ? -36.23132 5.87048   -45.63374 1.000 50.99186  ? 41  HIS B ND1  1 
ATOM   5198 C CD2  . HIS B 1 41  ? -37.74908 6.60803   -44.24784 1.000 38.65358  ? 41  HIS B CD2  1 
ATOM   5199 C CE1  . HIS B 1 41  ? -35.82366 5.56955   -44.41388 1.000 45.57944  ? 41  HIS B CE1  1 
ATOM   5200 N NE2  . HIS B 1 41  ? -36.72521 6.00872   -43.55425 1.000 45.10691  ? 41  HIS B NE2  1 
ATOM   5201 H H    . HIS B 1 41  ? -36.23478 8.53224   -47.12487 1.000 42.21564  ? 41  HIS B H    1 
ATOM   5202 H HA   . HIS B 1 41  ? -38.82458 8.67360   -47.72591 1.000 52.35548  ? 41  HIS B HA   1 
ATOM   5203 H HB2  . HIS B 1 41  ? -39.08687 6.66788   -46.70872 1.000 45.40282  ? 41  HIS B HB2  1 
ATOM   5204 H HB3  . HIS B 1 41  ? -37.74234 6.59853   -47.55301 1.000 45.40282  ? 41  HIS B HB3  1 
ATOM   5205 H HD2  . HIS B 1 41  ? -38.51445 6.98939   -43.88223 1.000 46.37806  ? 41  HIS B HD2  1 
ATOM   5206 H HE1  . HIS B 1 41  ? -35.03633 5.12447   -44.19729 1.000 54.68910  ? 41  HIS B HE1  1 
ATOM   5207 H HE2  . HIS B 1 41  ? -36.67896 5.93202   -42.69893 1.000 54.12206  ? 41  HIS B HE2  1 
ATOM   5208 N N    . VAL B 1 42  ? -38.22123 10.32778  -45.31841 1.000 37.23836  ? 42  VAL B N    1 
ATOM   5209 C CA   . VAL B 1 42  ? -38.87295 11.19947  -44.34864 1.000 44.92724  ? 42  VAL B CA   1 
ATOM   5210 C C    . VAL B 1 42  ? -40.12934 11.83225  -44.93416 1.000 48.27276  ? 42  VAL B C    1 
ATOM   5211 O O    . VAL B 1 42  ? -40.96322 12.35882  -44.19117 1.000 49.93965  ? 42  VAL B O    1 
ATOM   5212 C CB   . VAL B 1 42  ? -37.89572 12.28996  -43.86144 1.000 40.03001  ? 42  VAL B CB   1 
ATOM   5213 C CG1  . VAL B 1 42  ? -37.60123 13.30108  -44.97239 1.000 43.09722  ? 42  VAL B CG1  1 
ATOM   5214 C CG2  . VAL B 1 42  ? -38.44231 12.98719  -42.61964 1.000 43.18238  ? 42  VAL B CG2  1 
ATOM   5215 H H    . VAL B 1 42  ? -37.44234 10.59495  -45.56649 1.000 44.67980  ? 42  VAL B H    1 
ATOM   5216 H HA   . VAL B 1 42  ? -39.13139 10.66453  -43.58186 1.000 53.90646  ? 42  VAL B HA   1 
ATOM   5217 H HB   . VAL B 1 42  ? -37.05685 11.86595  -43.62180 1.000 48.02978  ? 42  VAL B HB   1 
ATOM   5218 H HG11 . VAL B 1 42  ? -36.93707 13.93332  -44.65605 1.000 51.71044  ? 42  VAL B HG11 1 
ATOM   5219 H HG12 . VAL B 1 42  ? -37.26387 12.82773  -45.74893 1.000 51.71044  ? 42  VAL B HG12 1 
ATOM   5220 H HG13 . VAL B 1 42  ? -38.42050 13.76799  -45.19975 1.000 51.71044  ? 42  VAL B HG13 1 
ATOM   5221 H HG21 . VAL B 1 42  ? -37.78205 13.62002  -42.29640 1.000 51.81262  ? 42  VAL B HG21 1 
ATOM   5222 H HG22 . VAL B 1 42  ? -39.26037 13.45308  -42.85337 1.000 51.81262  ? 42  VAL B HG22 1 
ATOM   5223 H HG23 . VAL B 1 42  ? -38.62399 12.32150  -41.93791 1.000 51.81262  ? 42  VAL B HG23 1 
ATOM   5224 N N    . ILE B 1 43  ? -40.28325 11.79089  -46.26449 1.000 49.25685  ? 43  ILE B N    1 
ATOM   5225 C CA   . ILE B 1 43  ? -41.43635 12.39126  -46.92449 1.000 47.18426  ? 43  ILE B CA   1 
ATOM   5226 C C    . ILE B 1 43  ? -42.54901 11.38653  -47.18096 1.000 49.03136  ? 43  ILE B C    1 
ATOM   5227 O O    . ILE B 1 43  ? -43.56178 11.74366  -47.79926 1.000 64.14352  ? 43  ILE B O    1 
ATOM   5228 C CB   . ILE B 1 43  ? -41.00226 13.05170  -48.25315 1.000 54.82663  ? 43  ILE B CB   1 
ATOM   5229 C CG1  . ILE B 1 43  ? -40.70182 11.99232  -49.32136 1.000 44.75052  ? 43  ILE B CG1  1 
ATOM   5230 C CG2  . ILE B 1 43  ? -39.78020 13.92996  -48.01699 1.000 49.25084  ? 43  ILE B CG2  1 
ATOM   5231 C CD1  . ILE B 1 43  ? -40.20673 12.56620  -50.64906 1.000 40.13220  ? 43  ILE B CD1  1 
ATOM   5232 H H    . ILE B 1 43  ? -39.72784 11.41778  -46.80478 1.000 59.10200  ? 43  ILE B H    1 
ATOM   5233 H HA   . ILE B 1 43  ? -41.79908 13.07587  -46.34084 1.000 56.61488  ? 43  ILE B HA   1 
ATOM   5234 H HB   . ILE B 1 43  ? -41.73412 13.60088  -48.57514 1.000 65.78572  ? 43  ILE B HB   1 
ATOM   5235 H HG12 . ILE B 1 43  ? -40.01464 11.39693  -48.98343 1.000 53.69439  ? 43  ILE B HG12 1 
ATOM   5236 H HG13 . ILE B 1 43  ? -41.51410 11.49344  -49.50086 1.000 53.69439  ? 43  ILE B HG13 1 
ATOM   5237 H HG21 . ILE B 1 43  ? -39.73164 14.59863  -48.71801 1.000 59.09478  ? 43  ILE B HG21 1 
ATOM   5238 H HG22 . ILE B 1 43  ? -39.86426 14.36229  -47.15274 1.000 59.09478  ? 43  ILE B HG22 1 
ATOM   5239 H HG23 . ILE B 1 43  ? -38.98468 13.37519  -48.03335 1.000 59.09478  ? 43  ILE B HG23 1 
ATOM   5240 H HD11 . ILE B 1 43  ? -40.02209 11.83549  -51.25969 1.000 48.15241  ? 43  ILE B HD11 1 
ATOM   5241 H HD12 . ILE B 1 43  ? -40.89372 13.14177  -51.02009 1.000 48.15241  ? 43  ILE B HD12 1 
ATOM   5242 H HD13 . ILE B 1 43  ? -39.39756 13.07699  -50.49018 1.000 48.15241  ? 43  ILE B HD13 1 
ATOM   5243 N N    . CYS B 1 44  ? -42.40064 10.14709  -46.72824 1.000 42.43570  ? 44  CYS B N    1 
ATOM   5244 C CA   . CYS B 1 44  ? -43.38233 9.11089   -47.00354 1.000 42.53828  ? 44  CYS B CA   1 
ATOM   5245 C C    . CYS B 1 44  ? -44.38103 8.99360   -45.86042 1.000 46.72827  ? 44  CYS B C    1 
ATOM   5246 O O    . CYS B 1 44  ? -44.04406 9.18488   -44.69064 1.000 47.00974  ? 44  CYS B O    1 
ATOM   5247 C CB   . CYS B 1 44  ? -42.69862 7.75926   -47.21950 1.000 46.22339  ? 44  CYS B CB   1 
ATOM   5248 S SG   . CYS B 1 44  ? -41.70341 7.64813   -48.71390 1.000 48.55003  ? 44  CYS B SG   1 
ATOM   5249 H H    . CYS B 1 44  ? -41.73344 9.88094   -46.25536 1.000 50.91661  ? 44  CYS B H    1 
ATOM   5250 H HA   . CYS B 1 44  ? -43.86672 9.34457   -47.81079 1.000 51.03971  ? 44  CYS B HA   1 
ATOM   5251 H HB2  . CYS B 1 44  ? -42.11334 7.58647   -46.46551 1.000 55.46183  ? 44  CYS B HB2  1 
ATOM   5252 H HB3  . CYS B 1 44  ? -43.38252 7.07343   -47.27259 1.000 55.46183  ? 44  CYS B HB3  1 
ATOM   5253 H HG   . CYS B 1 44  ? -41.21621 6.55337   -48.77832 1.000 58.25381  ? 44  CYS B HG   1 
ATOM   5254 N N    . THR B 1 45  ? -45.62455 8.68063   -46.21782 1.000 49.37882  ? 45  THR B N    1 
ATOM   5255 C CA   . THR B 1 45  ? -46.62022 8.26728   -45.24397 1.000 57.69721  ? 45  THR B CA   1 
ATOM   5256 C C    . THR B 1 45  ? -46.42323 6.78552   -44.92807 1.000 54.60619  ? 45  THR B C    1 
ATOM   5257 O O    . THR B 1 45  ? -45.52924 6.12362   -45.46315 1.000 59.09544  ? 45  THR B O    1 
ATOM   5258 C CB   . THR B 1 45  ? -48.02803 8.53033   -45.77425 1.000 50.19546  ? 45  THR B CB   1 
ATOM   5259 O OG1  . THR B 1 45  ? -48.27285 7.69856   -46.91606 1.000 52.08847  ? 45  THR B OG1  1 
ATOM   5260 C CG2  . THR B 1 45  ? -48.18442 9.99156   -46.17369 1.000 46.70913  ? 45  THR B CG2  1 
ATOM   5261 H H    . THR B 1 45  ? -45.91543 8.70112   -47.02687 1.000 59.24836  ? 45  THR B H    1 
ATOM   5262 H HA   . THR B 1 45  ? -46.50792 8.78516   -44.43151 1.000 69.23043  ? 45  THR B HA   1 
ATOM   5263 H HB   . THR B 1 45  ? -48.67740 8.33094   -45.08182 1.000 60.22832  ? 45  THR B HB   1 
ATOM   5264 H HG1  . THR B 1 45  ? -48.98772 7.92958   -47.29182 1.000 62.49994  ? 45  THR B HG1  1 
ATOM   5265 H HG21 . THR B 1 45  ? -47.97124 10.56575  -45.42152 1.000 56.04472  ? 45  THR B HG21 1 
ATOM   5266 H HG22 . THR B 1 45  ? -47.58666 10.20043  -46.90851 1.000 56.04472  ? 45  THR B HG22 1 
ATOM   5267 H HG23 . THR B 1 45  ? -49.09756 10.16349  -46.45210 1.000 56.04472  ? 45  THR B HG23 1 
ATOM   5268 N N    . SER B 1 46  ? -47.26615 6.25009   -44.04319 1.000 63.31891  ? 46  SER B N    1 
ATOM   5269 C CA   . SER B 1 46  ? -47.25126 4.81022   -43.80519 1.000 57.57511  ? 46  SER B CA   1 
ATOM   5270 C C    . SER B 1 46  ? -47.50939 4.04251   -45.09729 1.000 60.18121  ? 46  SER B C    1 
ATOM   5271 O O    . SER B 1 46  ? -46.85051 3.03290   -45.37468 1.000 64.31595  ? 46  SER B O    1 
ATOM   5272 C CB   . SER B 1 46  ? -48.29099 4.44312   -42.74635 1.000 60.71145  ? 46  SER B CB   1 
ATOM   5273 H H    . SER B 1 46  ? -47.84221 6.68887   -43.57927 1.000 75.97647  ? 46  SER B H    1 
ATOM   5274 H HA   . SER B 1 46  ? -46.37825 4.55450   -43.46848 1.000 69.08390  ? 46  SER B HA   1 
ATOM   5275 N N    . GLU B 1 47  ? -48.45802 4.51581   -45.90877 1.000 58.87099  ? 47  GLU B N    1 
ATOM   5276 C CA   . GLU B 1 47  ? -48.78802 3.81579   -47.14555 1.000 59.53665  ? 47  GLU B CA   1 
ATOM   5277 C C    . GLU B 1 47  ? -47.71019 4.00604   -48.20769 1.000 58.32145  ? 47  GLU B C    1 
ATOM   5278 O O    . GLU B 1 47  ? -47.36220 3.05734   -48.91944 1.000 58.25230  ? 47  GLU B O    1 
ATOM   5279 C CB   . GLU B 1 47  ? -50.13844 4.29590   -47.68121 1.000 61.27881  ? 47  GLU B CB   1 
ATOM   5280 C CG   . GLU B 1 47  ? -51.34903 3.74472   -46.94113 1.000 75.85193  ? 47  GLU B CG   1 
ATOM   5281 C CD   . GLU B 1 47  ? -52.55343 3.55986   -47.85159 1.000 93.16333  ? 47  GLU B CD   1 
ATOM   5282 O OE1  . GLU B 1 47  ? -52.61320 4.22621   -48.90707 1.000 89.04387  ? 47  GLU B OE1  1 
ATOM   5283 O OE2  . GLU B 1 47  ? -53.43585 2.74025   -47.51693 1.000 96.34430  ? 47  GLU B OE2  1 
ATOM   5284 H H    . GLU B 1 47  ? -48.91709 5.22908   -45.76694 1.000 70.63896  ? 47  GLU B H    1 
ATOM   5285 H HA   . GLU B 1 47  ? -48.85387 2.86859   -46.94709 1.000 71.43776  ? 47  GLU B HA   1 
ATOM   5286 H HB2  . GLU B 1 47  ? -50.17038 5.26303   -47.61385 1.000 73.52835  ? 47  GLU B HB2  1 
ATOM   5287 H HB3  . GLU B 1 47  ? -50.21550 4.02526   -48.60950 1.000 73.52835  ? 47  GLU B HB3  1 
ATOM   5288 H HG2  . GLU B 1 47  ? -51.12277 2.88096   -46.56215 1.000 91.01609  ? 47  GLU B HG2  1 
ATOM   5289 H HG3  . GLU B 1 47  ? -51.59722 4.36198   -46.23523 1.000 91.01609  ? 47  GLU B HG3  1 
ATOM   5290 N N    . ASP B 1 48  ? -47.17682 5.22464   -48.33723 1.000 54.51771  ? 48  ASP B N    1 
ATOM   5291 C CA   . ASP B 1 48  ? -46.26667 5.52287   -49.44131 1.000 53.57958  ? 48  ASP B CA   1 
ATOM   5292 C C    . ASP B 1 48  ? -45.08254 4.56391   -49.48486 1.000 54.42212  ? 48  ASP B C    1 
ATOM   5293 O O    . ASP B 1 48  ? -44.60883 4.21037   -50.57356 1.000 52.67866  ? 48  ASP B O    1 
ATOM   5294 C CB   . ASP B 1 48  ? -45.76103 6.96312   -49.33001 1.000 53.52264  ? 48  ASP B CB   1 
ATOM   5295 C CG   . ASP B 1 48  ? -46.76918 7.97918   -49.83395 1.000 62.01015  ? 48  ASP B CG   1 
ATOM   5296 O OD1  . ASP B 1 48  ? -47.55433 7.64493   -50.74977 1.000 68.54283  ? 48  ASP B OD1  1 
ATOM   5297 O OD2  . ASP B 1 48  ? -46.77275 9.11757   -49.31653 1.000 63.47426  ? 48  ASP B OD2  1 
ATOM   5298 H H    . ASP B 1 48  ? -47.32421 5.88541   -47.80689 1.000 65.41502  ? 48  ASP B H    1 
ATOM   5299 H HA   . ASP B 1 48  ? -46.75852 5.42992   -50.27218 1.000 64.28927  ? 48  ASP B HA   1 
ATOM   5300 H HB2  . ASP B 1 48  ? -45.57463 7.16172   -48.39903 1.000 64.22094  ? 48  ASP B HB2  1 
ATOM   5301 H HB3  . ASP B 1 48  ? -44.95225 7.05593   -49.85741 1.000 64.22094  ? 48  ASP B HB3  1 
ATOM   5302 N N    . MET B 1 49  ? -44.59810 4.12759   -48.32245 1.000 50.15499  ? 49  MET B N    1 
ATOM   5303 C CA   . MET B 1 49  ? -43.37019 3.34258   -48.27201 1.000 50.39925  ? 49  MET B CA   1 
ATOM   5304 C C    . MET B 1 49  ? -43.48231 2.01836   -49.01610 1.000 49.70805  ? 49  MET B C    1 
ATOM   5305 O O    . MET B 1 49  ? -42.45252 1.43808   -49.37649 1.000 44.80659  ? 49  MET B O    1 
ATOM   5306 C CB   . MET B 1 49  ? -42.97949 3.09183   -46.81459 1.000 53.25536  ? 49  MET B CB   1 
ATOM   5307 C CG   . MET B 1 49  ? -42.19399 4.23533   -46.19328 1.000 56.04200  ? 49  MET B CG   1 
ATOM   5308 S SD   . MET B 1 49  ? -42.43232 4.38119   -44.41186 1.000 71.32711  ? 49  MET B SD   1 
ATOM   5309 C CE   . MET B 1 49  ? -41.41256 5.81479   -44.06134 1.000 58.70297  ? 49  MET B CE   1 
ATOM   5310 H H    . MET B 1 49  ? -44.95943 4.27196   -47.55551 1.000 60.17976  ? 49  MET B H    1 
ATOM   5311 H HA   . MET B 1 49  ? -42.66379 3.85913   -48.69043 1.000 60.47287  ? 49  MET B HA   1 
ATOM   5312 H HB2  . MET B 1 49  ? -43.78660 2.96661   -46.29134 1.000 63.90020  ? 49  MET B HB2  1 
ATOM   5313 H HB3  . MET B 1 49  ? -42.42879 2.29451   -46.77097 1.000 63.90020  ? 49  MET B HB3  1 
ATOM   5314 H HG2  . MET B 1 49  ? -41.24863 4.09153   -46.35611 1.000 67.24418  ? 49  MET B HG2  1 
ATOM   5315 H HG3  . MET B 1 49  ? -42.47778 5.06869   -46.60056 1.000 67.24418  ? 49  MET B HG3  1 
ATOM   5316 H HE1  . MET B 1 49  ? -40.86114 6.00708   -44.83585 1.000 70.43734  ? 49  MET B HE1  1 
ATOM   5317 H HE2  . MET B 1 49  ? -41.98755 6.57182   -43.86850 1.000 70.43734  ? 49  MET B HE2  1 
ATOM   5318 H HE3  . MET B 1 49  ? -40.85041 5.62261   -43.29456 1.000 70.43734  ? 49  MET B HE3  1 
ATOM   5319 N N    . LEU B 1 50  ? -44.69843 1.52898   -49.26439 1.000 45.07290  ? 50  LEU B N    1 
ATOM   5320 C CA   . LEU B 1 50  ? -44.84370 0.24061   -49.93495 1.000 42.95949  ? 50  LEU B CA   1 
ATOM   5321 C C    . LEU B 1 50  ? -44.43372 0.32051   -51.40056 1.000 45.36972  ? 50  LEU B C    1 
ATOM   5322 O O    . LEU B 1 50  ? -43.95359 -0.67121  -51.96121 1.000 49.43067  ? 50  LEU B O    1 
ATOM   5323 C CB   . LEU B 1 50  ? -46.28284 -0.25504  -49.79505 1.000 45.09487  ? 50  LEU B CB   1 
ATOM   5324 C CG   . LEU B 1 50  ? -46.68585 -0.55945  -48.34877 1.000 46.59169  ? 50  LEU B CG   1 
ATOM   5325 C CD1  . LEU B 1 50  ? -48.18412 -0.42656  -48.16064 1.000 51.98552  ? 50  LEU B CD1  1 
ATOM   5326 C CD2  . LEU B 1 50  ? -46.21691 -1.95436  -47.94673 1.000 43.33422  ? 50  LEU B CD2  1 
ATOM   5327 H H    . LEU B 1 50  ? -45.43870 1.91548   -49.05890 1.000 54.08125  ? 50  LEU B H    1 
ATOM   5328 H HA   . LEU B 1 50  ? -44.26421 -0.40890  -49.50689 1.000 51.54516  ? 50  LEU B HA   1 
ATOM   5329 H HB2  . LEU B 1 50  ? -46.88258 0.42784   -50.13401 1.000 54.10761  ? 50  LEU B HB2  1 
ATOM   5330 H HB3  . LEU B 1 50  ? -46.38365 -1.07062  -50.31039 1.000 54.10761  ? 50  LEU B HB3  1 
ATOM   5331 H HG   . LEU B 1 50  ? -46.25761 0.08609   -47.76500 1.000 55.90380  ? 50  LEU B HG   1 
ATOM   5332 H HD11 . LEU B 1 50  ? -48.42606 0.51170   -48.20566 1.000 62.37639  ? 50  LEU B HD11 1 
ATOM   5333 H HD12 . LEU B 1 50  ? -48.63561 -0.91870  -48.86409 1.000 62.37639  ? 50  LEU B HD12 1 
ATOM   5334 H HD13 . LEU B 1 50  ? -48.42709 -0.78962  -47.29458 1.000 62.37639  ? 50  LEU B HD13 1 
ATOM   5335 H HD21 . LEU B 1 50  ? -46.26172 -2.03653  -46.98126 1.000 51.99483  ? 50  LEU B HD21 1 
ATOM   5336 H HD22 . LEU B 1 50  ? -46.79466 -2.61365  -48.36199 1.000 51.99483  ? 50  LEU B HD22 1 
ATOM   5337 H HD23 . LEU B 1 50  ? -45.30313 -2.07916  -48.24728 1.000 51.99483  ? 50  LEU B HD23 1 
ATOM   5338 N N    . ASN B 1 51  ? -44.60733 1.48063   -52.03370 1.000 57.32661  ? 51  ASN B N    1 
ATOM   5339 C CA   . ASN B 1 51  ? -44.11973 1.70058   -53.39086 1.000 51.74505  ? 51  ASN B CA   1 
ATOM   5340 C C    . ASN B 1 51  ? -44.04752 3.19573   -53.67089 1.000 50.15820  ? 51  ASN B C    1 
ATOM   5341 O O    . ASN B 1 51  ? -44.94581 3.75625   -54.31277 1.000 43.68998  ? 51  ASN B O    1 
ATOM   5342 C CB   . ASN B 1 51  ? -45.01173 1.01424   -54.42439 1.000 51.41427  ? 51  ASN B CB   1 
ATOM   5343 C CG   . ASN B 1 51  ? -44.45419 1.12282   -55.83227 1.000 53.67456  ? 51  ASN B CG   1 
ATOM   5344 O OD1  . ASN B 1 51  ? -43.48959 0.44324   -56.18355 1.000 54.75651  ? 51  ASN B OD1  1 
ATOM   5345 N ND2  . ASN B 1 51  ? -45.05629 1.98428   -56.64409 1.000 70.50585  ? 51  ASN B ND2  1 
ATOM   5346 H H    . ASN B 1 51  ? -45.00846 2.16122   -51.69385 1.000 68.78571  ? 51  ASN B H    1 
ATOM   5347 H HA   . ASN B 1 51  ? -43.23106 1.31998   -53.47024 1.000 62.08783  ? 51  ASN B HA   1 
ATOM   5348 H HB2  . ASN B 1 51  ? -45.08884 0.07314   -54.20236 1.000 61.69089  ? 51  ASN B HB2  1 
ATOM   5349 H HB3  . ASN B 1 51  ? -45.88785 1.43041   -54.41410 1.000 61.69089  ? 51  ASN B HB3  1 
ATOM   5350 H HD21 . ASN B 1 51  ? -45.72562 2.44492   -56.36229 1.000 84.60080  ? 51  ASN B HD21 1 
ATOM   5351 H HD22 . ASN B 1 51  ? -44.77688 2.08148   -57.45161 1.000 84.60080  ? 51  ASN B HD22 1 
ATOM   5352 N N    . PRO B 1 52  ? -42.99614 3.86952   -53.21651 1.000 41.15090  ? 52  PRO B N    1 
ATOM   5353 C CA   . PRO B 1 52  ? -42.92687 5.32248   -53.38163 1.000 42.80044  ? 52  PRO B CA   1 
ATOM   5354 C C    . PRO B 1 52  ? -42.40209 5.72427   -54.75090 1.000 39.11208  ? 52  PRO B C    1 
ATOM   5355 O O    . PRO B 1 52  ? -41.53920 5.06411   -55.33450 1.000 38.85616  ? 52  PRO B O    1 
ATOM   5356 C CB   . PRO B 1 52  ? -41.96508 5.75436   -52.26563 1.000 48.30041  ? 52  PRO B CB   1 
ATOM   5357 C CG   . PRO B 1 52  ? -41.13548 4.51756   -51.94509 1.000 43.16014  ? 52  PRO B CG   1 
ATOM   5358 C CD   . PRO B 1 52  ? -41.77218 3.32057   -52.60799 1.000 42.32116  ? 52  PRO B CD   1 
ATOM   5359 H HA   . PRO B 1 52  ? -43.79891 5.72467   -53.24489 1.000 51.35430  ? 52  PRO B HA   1 
ATOM   5360 H HB2  . PRO B 1 52  ? -41.40023 6.47739   -52.58038 1.000 57.95427  ? 52  PRO B HB2  1 
ATOM   5361 H HB3  . PRO B 1 52  ? -42.47064 6.04214   -51.48943 1.000 57.95427  ? 52  PRO B HB3  1 
ATOM   5362 H HG2  . PRO B 1 52  ? -40.23537 4.64554   -52.28320 1.000 51.78594  ? 52  PRO B HG2  1 
ATOM   5363 H HG3  . PRO B 1 52  ? -41.11403 4.39305   -50.98335 1.000 51.78594  ? 52  PRO B HG3  1 
ATOM   5364 H HD2  . PRO B 1 52  ? -41.18621 2.95164   -53.28727 1.000 50.77916  ? 52  PRO B HD2  1 
ATOM   5365 H HD3  . PRO B 1 52  ? -41.98983 2.63975   -51.95224 1.000 50.77916  ? 52  PRO B HD3  1 
ATOM   5366 N N    . ASN B 1 53  ? -42.96160 6.80911   -55.27128 1.000 46.98522  ? 53  ASN B N    1 
ATOM   5367 C CA   . ASN B 1 53  ? -42.39106 7.55745   -56.38873 1.000 47.18925  ? 53  ASN B CA   1 
ATOM   5368 C C    . ASN B 1 53  ? -41.87413 8.84789   -55.75546 1.000 44.42659  ? 53  ASN B C    1 
ATOM   5369 O O    . ASN B 1 53  ? -42.61818 9.81626   -55.58822 1.000 39.07285  ? 53  ASN B O    1 
ATOM   5370 C CB   . ASN B 1 53  ? -43.41748 7.81454   -57.48810 1.000 44.11511  ? 53  ASN B CB   1 
ATOM   5371 C CG   . ASN B 1 53  ? -42.82480 8.53672   -58.68597 1.000 47.24207  ? 53  ASN B CG   1 
ATOM   5372 O OD1  . ASN B 1 53  ? -42.08363 9.51337   -58.54066 1.000 42.69215  ? 53  ASN B OD1  1 
ATOM   5373 N ND2  . ASN B 1 53  ? -43.14623 8.05314   -59.88077 1.000 46.30127  ? 53  ASN B ND2  1 
ATOM   5374 H H    . ASN B 1 53  ? -43.69959 7.14474   -54.98434 1.000 56.37604  ? 53  ASN B H    1 
ATOM   5375 H HA   . ASN B 1 53  ? -41.66542 7.06790   -56.80670 1.000 56.62087  ? 53  ASN B HA   1 
ATOM   5376 H HB2  . ASN B 1 53  ? -43.77199 6.96532   -57.79477 1.000 52.93191  ? 53  ASN B HB2  1 
ATOM   5377 H HB3  . ASN B 1 53  ? -44.13314 8.36317   -57.13070 1.000 52.93191  ? 53  ASN B HB3  1 
ATOM   5378 H HD21 . ASN B 1 53  ? -43.66289 7.36844   -59.94274 1.000 55.55529  ? 53  ASN B HD21 1 
ATOM   5379 H HD22 . ASN B 1 53  ? -42.83764 8.42477   -60.59229 1.000 55.55529  ? 53  ASN B HD22 1 
ATOM   5380 N N    . TYR B 1 54  ? -40.59445 8.84407   -55.37849 1.000 38.55537  ? 54  TYR B N    1 
ATOM   5381 C CA   . TYR B 1 54  ? -40.07449 9.91800   -54.53959 1.000 43.31127  ? 54  TYR B CA   1 
ATOM   5382 C C    . TYR B 1 54  ? -40.10943 11.26538  -55.25049 1.000 41.62298  ? 54  TYR B C    1 
ATOM   5383 O O    . TYR B 1 54  ? -40.36028 12.29364  -54.61548 1.000 43.17657  ? 54  TYR B O    1 
ATOM   5384 C CB   . TYR B 1 54  ? -38.65998 9.57980   -54.07244 1.000 37.98024  ? 54  TYR B CB   1 
ATOM   5385 C CG   . TYR B 1 54  ? -38.63665 8.60348   -52.91249 1.000 41.20886  ? 54  TYR B CG   1 
ATOM   5386 C CD1  . TYR B 1 54  ? -39.02828 9.00168   -51.64103 1.000 38.95756  ? 54  TYR B CD1  1 
ATOM   5387 C CD2  . TYR B 1 54  ? -38.22937 7.28602   -53.08738 1.000 37.93944  ? 54  TYR B CD2  1 
ATOM   5388 C CE1  . TYR B 1 54  ? -39.01335 8.11965   -50.57796 1.000 39.40978  ? 54  TYR B CE1  1 
ATOM   5389 C CE2  . TYR B 1 54  ? -38.20655 6.39756   -52.02617 1.000 37.80404  ? 54  TYR B CE2  1 
ATOM   5390 C CZ   . TYR B 1 54  ? -38.60344 6.81907   -50.77514 1.000 35.87451  ? 54  TYR B CZ   1 
ATOM   5391 O OH   . TYR B 1 54  ? -38.58499 5.93614   -49.72029 1.000 38.75459  ? 54  TYR B OH   1 
ATOM   5392 H H    . TYR B 1 54  ? -40.01849 8.24203   -55.59159 1.000 46.26022  ? 54  TYR B H    1 
ATOM   5393 H HA   . TYR B 1 54  ? -40.63853 9.99461   -53.75416 1.000 51.96730  ? 54  TYR B HA   1 
ATOM   5394 H HB2  . TYR B 1 54  ? -38.17208 9.18049   -54.80959 1.000 45.57005  ? 54  TYR B HB2  1 
ATOM   5395 H HB3  . TYR B 1 54  ? -38.21962 10.39528  -53.78615 1.000 45.57005  ? 54  TYR B HB3  1 
ATOM   5396 H HD1  . TYR B 1 54  ? -39.30577 9.87847   -51.50266 1.000 46.74284  ? 54  TYR B HD1  1 
ATOM   5397 H HD2  . TYR B 1 54  ? -37.96780 6.99661   -53.93161 1.000 45.52110  ? 54  TYR B HD2  1 
ATOM   5398 H HE1  . TYR B 1 54  ? -39.27887 8.40251   -49.73274 1.000 47.28551  ? 54  TYR B HE1  1 
ATOM   5399 H HE2  . TYR B 1 54  ? -37.92493 5.52086   -52.15651 1.000 45.35862  ? 54  TYR B HE2  1 
ATOM   5400 H HH   . TYR B 1 54  ? -38.35132 5.17467   -49.98705 1.000 46.49928  ? 54  TYR B HH   1 
ATOM   5401 N N    . GLU B 1 55  ? -39.87045 11.28790  -56.56549 1.000 44.11221  ? 55  GLU B N    1 
ATOM   5402 C CA   . GLU B 1 55  ? -39.96688 12.54563  -57.30226 1.000 47.30490  ? 55  GLU B CA   1 
ATOM   5403 C C    . GLU B 1 55  ? -41.34912 13.16656  -57.13233 1.000 47.29344  ? 55  GLU B C    1 
ATOM   5404 O O    . GLU B 1 55  ? -41.47802 14.34648  -56.78549 1.000 43.88459  ? 55  GLU B O    1 
ATOM   5405 C CB   . GLU B 1 55  ? -39.66289 12.31376  -58.78310 1.000 51.32383  ? 55  GLU B CB   1 
ATOM   5406 C CG   . GLU B 1 55  ? -38.33710 11.62130  -59.05601 1.000 59.11668  ? 55  GLU B CG   1 
ATOM   5407 C CD   . GLU B 1 55  ? -37.31130 12.53697  -59.69889 1.000 70.82541  ? 55  GLU B CD   1 
ATOM   5408 O OE1  . GLU B 1 55  ? -37.04052 13.62160  -59.13953 1.000 76.15118  ? 55  GLU B OE1  1 
ATOM   5409 O OE2  . GLU B 1 55  ? -36.77736 12.16864  -60.76724 1.000 61.18648  ? 55  GLU B OE2  1 
ATOM   5410 H H    . GLU B 1 55  ? -39.65603 10.60438  -57.04134 1.000 52.92842  ? 55  GLU B H    1 
ATOM   5411 H HA   . GLU B 1 55  ? -39.30636 13.16465  -56.95378 1.000 56.75965  ? 55  GLU B HA   1 
ATOM   5412 H HB2  . GLU B 1 55  ? -40.36499 11.76014  -59.15921 1.000 61.58237  ? 55  GLU B HB2  1 
ATOM   5413 H HB3  . GLU B 1 55  ? -39.64185 13.17336  -59.23204 1.000 61.58237  ? 55  GLU B HB3  1 
ATOM   5414 H HG2  . GLU B 1 55  ? -37.96925 11.30278  -58.21689 1.000 70.93379  ? 55  GLU B HG2  1 
ATOM   5415 H HG3  . GLU B 1 55  ? -38.48916 10.87466  -59.65627 1.000 70.93379  ? 55  GLU B HG3  1 
ATOM   5416 N N    . ASP B 1 56  ? -42.39989 12.37771  -57.36668 1.000 44.66868  ? 56  ASP B N    1 
ATOM   5417 C CA   . ASP B 1 56  ? -43.75586 12.89736  -57.23091 1.000 41.82403  ? 56  ASP B CA   1 
ATOM   5418 C C    . ASP B 1 56  ? -44.06846 13.26315  -55.78392 1.000 51.82115  ? 56  ASP B C    1 
ATOM   5419 O O    . ASP B 1 56  ? -44.67733 14.30712  -55.52150 1.000 49.92949  ? 56  ASP B O    1 
ATOM   5420 C CB   . ASP B 1 56  ? -44.76002 11.87457  -57.76261 1.000 48.90808  ? 56  ASP B CB   1 
ATOM   5421 C CG   . ASP B 1 56  ? -44.71678 11.74695  -59.27748 1.000 57.22790  ? 56  ASP B CG   1 
ATOM   5422 O OD1  . ASP B 1 56  ? -44.34293 12.73359  -59.94780 1.000 52.46946  ? 56  ASP B OD1  1 
ATOM   5423 O OD2  . ASP B 1 56  ? -45.06056 10.66358  -59.79928 1.000 59.85026  ? 56  ASP B OD2  1 
ATOM   5424 H H    . ASP B 1 56  ? -42.35375 11.55172  -57.60164 1.000 53.59619  ? 56  ASP B H    1 
ATOM   5425 H HA   . ASP B 1 56  ? -43.83853 13.70386  -57.76348 1.000 50.18261  ? 56  ASP B HA   1 
ATOM   5426 H HB2  . ASP B 1 56  ? -44.55877 11.00547  -57.38175 1.000 58.68347  ? 56  ASP B HB2  1 
ATOM   5427 H HB3  . ASP B 1 56  ? -45.65542 12.14848  -57.50935 1.000 58.68347  ? 56  ASP B HB3  1 
ATOM   5428 N N    . LEU B 1 57  ? -43.65555 12.42619  -54.82896 1.000 45.69349  ? 57  LEU B N    1 
ATOM   5429 C CA   . LEU B 1 57  ? -43.93516 12.72576  -53.42768 1.000 49.44808  ? 57  LEU B CA   1 
ATOM   5430 C C    . LEU B 1 57  ? -43.22068 13.99676  -52.98491 1.000 46.13863  ? 57  LEU B C    1 
ATOM   5431 O O    . LEU B 1 57  ? -43.77718 14.80046  -52.22720 1.000 43.41801  ? 57  LEU B O    1 
ATOM   5432 C CB   . LEU B 1 57  ? -43.53025 11.54436  -52.54610 1.000 45.64422  ? 57  LEU B CB   1 
ATOM   5433 C CG   . LEU B 1 57  ? -44.40743 10.29404  -52.64598 1.000 46.36568  ? 57  LEU B CG   1 
ATOM   5434 C CD1  . LEU B 1 57  ? -43.74225 9.11686   -51.94445 1.000 49.83575  ? 57  LEU B CD1  1 
ATOM   5435 C CD2  . LEU B 1 57  ? -45.78902 10.55030  -52.06204 1.000 46.48868  ? 57  LEU B CD2  1 
ATOM   5436 H H    . LEU B 1 57  ? -43.22201 11.69585  -54.96407 1.000 54.82596  ? 57  LEU B H    1 
ATOM   5437 H HA   . LEU B 1 57  ? -44.88929 12.86405  -53.32090 1.000 59.33147  ? 57  LEU B HA   1 
ATOM   5438 H HB2  . LEU B 1 57  ? -42.62873 11.28171  -52.78933 1.000 54.76683  ? 57  LEU B HB2  1 
ATOM   5439 H HB3  . LEU B 1 57  ? -43.55260 11.83657  -51.62143 1.000 54.76683  ? 57  LEU B HB3  1 
ATOM   5440 H HG   . LEU B 1 57  ? -44.51820 10.06686  -53.58247 1.000 55.63259  ? 57  LEU B HG   1 
ATOM   5441 H HD11 . LEU B 1 57  ? -43.64427 9.32513   -51.00215 1.000 59.79667  ? 57  LEU B HD11 1 
ATOM   5442 H HD12 . LEU B 1 57  ? -44.29810 8.32937   -52.05310 1.000 59.79667  ? 57  LEU B HD12 1 
ATOM   5443 H HD13 . LEU B 1 57  ? -42.87068 8.96392   -52.34178 1.000 59.79667  ? 57  LEU B HD13 1 
ATOM   5444 H HD21 . LEU B 1 57  ? -46.27332 9.71108   -52.01668 1.000 55.78019  ? 57  LEU B HD21 1 
ATOM   5445 H HD22 . LEU B 1 57  ? -45.69144 10.92439  -51.17241 1.000 55.78019  ? 57  LEU B HD22 1 
ATOM   5446 H HD23 . LEU B 1 57  ? -46.26249 11.17497  -52.63345 1.000 55.78019  ? 57  LEU B HD23 1 
ATOM   5447 N N    . LEU B 1 58  ? -41.98608 14.19796  -53.45095 1.000 49.23135  ? 58  LEU B N    1 
ATOM   5448 C CA   . LEU B 1 58  ? -41.24224 15.39579  -53.07897 1.000 50.89250  ? 58  LEU B CA   1 
ATOM   5449 C C    . LEU B 1 58  ? -41.81315 16.63422  -53.75551 1.000 49.32031  ? 58  LEU B C    1 
ATOM   5450 O O    . LEU B 1 58  ? -41.80264 17.72493  -53.17159 1.000 49.78297  ? 58  LEU B O    1 
ATOM   5451 C CB   . LEU B 1 58  ? -39.76887 15.22810  -53.44706 1.000 50.13144  ? 58  LEU B CB   1 
ATOM   5452 C CG   . LEU B 1 58  ? -38.88462 16.43949  -53.15454 1.000 49.75371  ? 58  LEU B CG   1 
ATOM   5453 C CD1  . LEU B 1 58  ? -38.81824 16.69157  -51.65688 1.000 51.70035  ? 58  LEU B CD1  1 
ATOM   5454 C CD2  . LEU B 1 58  ? -37.49886 16.24625  -53.74258 1.000 45.55297  ? 58  LEU B CD2  1 
ATOM   5455 H H    . LEU B 1 58  ? -41.56450 13.66305  -53.97606 1.000 59.07139  ? 58  LEU B H    1 
ATOM   5456 H HA   . LEU B 1 58  ? -41.30193 15.51904  -52.11868 1.000 61.06478  ? 58  LEU B HA   1 
ATOM   5457 H HB2  . LEU B 1 58  ? -39.41158 14.47911  -52.94480 1.000 60.15150  ? 58  LEU B HB2  1 
ATOM   5458 H HB3  . LEU B 1 58  ? -39.70998 15.04792  -54.39836 1.000 60.15150  ? 58  LEU B HB3  1 
ATOM   5459 H HG   . LEU B 1 58  ? -39.26874 17.22636  -53.57190 1.000 59.69822  ? 58  LEU B HG   1 
ATOM   5460 H HD11 . LEU B 1 58  ? -38.65554 15.85045  -51.20197 1.000 62.03420  ? 58  LEU B HD11 1 
ATOM   5461 H HD12 . LEU B 1 58  ? -38.09594 17.31230  -51.47282 1.000 62.03420  ? 58  LEU B HD12 1 
ATOM   5462 H HD13 . LEU B 1 58  ? -39.66188 17.06906  -51.36248 1.000 62.03420  ? 58  LEU B HD13 1 
ATOM   5463 H HD21 . LEU B 1 58  ? -37.05571 15.52106  -53.27501 1.000 54.65734  ? 58  LEU B HD21 1 
ATOM   5464 H HD22 . LEU B 1 58  ? -37.58281 16.03011  -54.68446 1.000 54.65734  ? 58  LEU B HD22 1 
ATOM   5465 H HD23 . LEU B 1 58  ? -36.99304 17.06694  -53.63533 1.000 54.65734  ? 58  LEU B HD23 1 
ATOM   5466 N N    . ILE B 1 59  ? -42.30368 16.48482  -54.98605 1.000 55.07812  ? 59  ILE B N    1 
ATOM   5467 C CA   . ILE B 1 59  ? -42.88373 17.60979  -55.71152 1.000 48.43915  ? 59  ILE B CA   1 
ATOM   5468 C C    . ILE B 1 59  ? -44.00510 18.26050  -54.91368 1.000 52.13917  ? 59  ILE B C    1 
ATOM   5469 O O    . ILE B 1 59  ? -44.24638 19.46696  -55.04130 1.000 64.20933  ? 59  ILE B O    1 
ATOM   5470 C CB   . ILE B 1 59  ? -43.36754 17.13237  -57.09760 1.000 52.06098  ? 59  ILE B CB   1 
ATOM   5471 C CG1  . ILE B 1 59  ? -42.17606 17.03491  -58.05704 1.000 57.55440  ? 59  ILE B CG1  1 
ATOM   5472 C CG2  . ILE B 1 59  ? -44.45015 18.05372  -57.64151 1.000 56.02213  ? 59  ILE B CG2  1 
ATOM   5473 C CD1  . ILE B 1 59  ? -42.42751 16.16298  -59.27460 1.000 67.04206  ? 59  ILE B CD1  1 
ATOM   5474 H H    . ILE B 1 59  ? -42.31224 15.74338  -55.42171 1.000 66.08752  ? 59  ILE B H    1 
ATOM   5475 H HA   . ILE B 1 59  ? -42.19938 18.28492  -55.84100 1.000 58.12075  ? 59  ILE B HA   1 
ATOM   5476 H HB   . ILE B 1 59  ? -43.75939 16.24974  -57.00632 1.000 62.46694  ? 59  ILE B HB   1 
ATOM   5477 H HG12 . ILE B 1 59  ? -41.95852 17.92583  -58.37302 1.000 69.05905  ? 59  ILE B HG12 1 
ATOM   5478 H HG13 . ILE B 1 59  ? -41.42124 16.65958  -57.57718 1.000 69.05905  ? 59  ILE B HG13 1 
ATOM   5479 H HG21 . ILE B 1 59  ? -44.51541 17.93197  -58.60162 1.000 67.22032  ? 59  ILE B HG21 1 
ATOM   5480 H HG22 . ILE B 1 59  ? -45.29545 17.83012  -57.22152 1.000 67.22032  ? 59  ILE B HG22 1 
ATOM   5481 H HG23 . ILE B 1 59  ? -44.21347 18.97254  -57.43992 1.000 67.22032  ? 59  ILE B HG23 1 
ATOM   5482 H HD11 . ILE B 1 59  ? -41.61184 16.10659  -59.79653 1.000 80.44424  ? 59  ILE B HD11 1 
ATOM   5483 H HD12 . ILE B 1 59  ? -42.69340 15.27796  -58.97977 1.000 80.44424  ? 59  ILE B HD12 1 
ATOM   5484 H HD13 . ILE B 1 59  ? -43.13415 16.56041  -59.80714 1.000 80.44424  ? 59  ILE B HD13 1 
ATOM   5485 N N    . ARG B 1 60  ? -44.70184 17.49151  -54.08158 1.000 49.63638  ? 60  ARG B N    1 
ATOM   5486 C CA   . ARG B 1 60  ? -45.81191 18.01471  -53.29587 1.000 54.47720  ? 60  ARG B CA   1 
ATOM   5487 C C    . ARG B 1 60  ? -45.38895 18.56881  -51.93769 1.000 67.37685  ? 60  ARG B C    1 
ATOM   5488 O O    . ARG B 1 60  ? -46.24778 19.05825  -51.19535 1.000 67.36576  ? 60  ARG B O    1 
ATOM   5489 C CB   . ARG B 1 60  ? -46.87087 16.92406  -53.10435 1.000 56.47758  ? 60  ARG B CB   1 
ATOM   5490 C CG   . ARG B 1 60  ? -47.81878 16.78175  -54.28951 1.000 73.02333  ? 60  ARG B CG   1 
ATOM   5491 C CD   . ARG B 1 60  ? -47.79778 15.37608  -54.86785 1.000 73.91391  ? 60  ARG B CD   1 
ATOM   5492 N NE   . ARG B 1 60  ? -48.33822 14.38923  -53.94005 1.000 78.86680  ? 60  ARG B NE   1 
ATOM   5493 C CZ   . ARG B 1 60  ? -48.28324 13.07716  -54.12575 1.000 74.86404  ? 60  ARG B CZ   1 
ATOM   5494 N NH1  . ARG B 1 60  ? -47.70078 12.55399  -55.19274 1.000 66.07773  ? 60  ARG B NH1  1 
ATOM   5495 N NH2  . ARG B 1 60  ? -48.82263 12.26974  -53.21606 1.000 69.26291  ? 60  ARG B NH2  1 
ATOM   5496 H H    . ARG B 1 60  ? -44.54808 16.65498  -53.95440 1.000 59.55743  ? 60  ARG B H    1 
ATOM   5497 H HA   . ARG B 1 60  ? -46.21711 18.74618  -53.78747 1.000 65.36641  ? 60  ARG B HA   1 
ATOM   5498 H HB2  . ARG B 1 60  ? -46.42358 16.07272  -52.97770 1.000 67.76687  ? 60  ARG B HB2  1 
ATOM   5499 H HB3  . ARG B 1 60  ? -47.40305 17.13880  -52.32232 1.000 67.76687  ? 60  ARG B HB3  1 
ATOM   5500 H HG2  . ARG B 1 60  ? -48.72383 16.97686  -54.00017 1.000 87.62177  ? 60  ARG B HG2  1 
ATOM   5501 H HG3  . ARG B 1 60  ? -47.55296 17.40060  -54.98754 1.000 87.62177  ? 60  ARG B HG3  1 
ATOM   5502 H HD2  . ARG B 1 60  ? -48.33413 15.35634  -55.67584 1.000 88.69047  ? 60  ARG B HD2  1 
ATOM   5503 H HD3  . ARG B 1 60  ? -46.88203 15.12936  -55.07142 1.000 88.69047  ? 60  ARG B HD3  1 
ATOM   5504 H HE   . ARG B 1 60  ? -48.71813 14.67744  -53.22437 1.000 94.63393  ? 60  ARG B HE   1 
ATOM   5505 H HH11 . ARG B 1 60  ? -47.34702 13.06768  -55.78484 1.000 79.28704  ? 60  ARG B HH11 1 
ATOM   5506 H HH12 . ARG B 1 60  ? -47.67605 11.70033  -55.29401 1.000 79.28704  ? 60  ARG B HH12 1 
ATOM   5507 H HH21 . ARG B 1 60  ? -49.20103 12.60029  -52.51810 1.000 83.10926  ? 60  ARG B HH21 1 
ATOM   5508 H HH22 . ARG B 1 60  ? -48.79288 11.41732  -53.32606 1.000 83.10926  ? 60  ARG B HH22 1 
ATOM   5509 N N    . LYS B 1 61  ? -44.10311 18.51196  -51.59613 1.000 66.74228  ? 61  LYS B N    1 
ATOM   5510 C CA   . LYS B 1 61  ? -43.58564 19.09578  -50.36696 1.000 62.29121  ? 61  LYS B CA   1 
ATOM   5511 C C    . LYS B 1 61  ? -43.00247 20.47863  -50.64002 1.000 64.01415  ? 61  LYS B C    1 
ATOM   5512 O O    . LYS B 1 61  ? -42.58968 20.79823  -51.75830 1.000 58.65049  ? 61  LYS B O    1 
ATOM   5513 C CB   . LYS B 1 61  ? -42.50575 18.20747  -49.74094 1.000 65.10836  ? 61  LYS B CB   1 
ATOM   5514 C CG   . LYS B 1 61  ? -42.95515 16.80071  -49.38253 1.000 60.73920  ? 61  LYS B CG   1 
ATOM   5515 C CD   . LYS B 1 61  ? -43.97229 16.79481  -48.25388 1.000 52.20824  ? 61  LYS B CD   1 
ATOM   5516 C CE   . LYS B 1 61  ? -44.26255 15.37624  -47.79713 1.000 60.90931  ? 61  LYS B CE   1 
ATOM   5517 N NZ   . LYS B 1 61  ? -45.17815 15.31784  -46.62100 1.000 57.96933  ? 61  LYS B NZ   1 
ATOM   5518 H H    . LYS B 1 61  ? -43.49846 18.13038  -52.07404 1.000 80.08451  ? 61  LYS B H    1 
ATOM   5519 H HA   . LYS B 1 61  ? -44.31463 19.17976  -49.73260 1.000 74.74322  ? 61  LYS B HA   1 
ATOM   5520 H HB2  . LYS B 1 61  ? -41.77257 18.12633  -50.37083 1.000 78.12381  ? 61  LYS B HB2  1 
ATOM   5521 H HB3  . LYS B 1 61  ? -42.19648 18.63024  -48.92453 1.000 78.12381  ? 61  LYS B HB3  1 
ATOM   5522 H HG2  . LYS B 1 61  ? -43.36387 16.38877  -50.15980 1.000 72.88081  ? 61  LYS B HG2  1 
ATOM   5523 H HG3  . LYS B 1 61  ? -42.18572 16.28277  -49.09860 1.000 72.88081  ? 61  LYS B HG3  1 
ATOM   5524 H HD2  . LYS B 1 61  ? -43.62276 17.29542  -47.50014 1.000 62.64366  ? 61  LYS B HD2  1 
ATOM   5525 H HD3  . LYS B 1 61  ? -44.80062 17.19448  -48.56216 1.000 62.64366  ? 61  LYS B HD3  1 
ATOM   5526 H HE2  . LYS B 1 61  ? -44.68018 14.88986  -48.52508 1.000 73.08494  ? 61  LYS B HE2  1 
ATOM   5527 H HE3  . LYS B 1 61  ? -43.42847 14.94843  -47.54773 1.000 73.08494  ? 61  LYS B HE3  1 
ATOM   5528 H HZ1  . LYS B 1 61  ? -44.74243 15.56002  -45.88371 1.000 69.55697  ? 61  LYS B HZ1  1 
ATOM   5529 H HZ2  . LYS B 1 61  ? -45.86665 15.86833  -46.74360 1.000 69.55697  ? 61  LYS B HZ2  1 
ATOM   5530 H HZ3  . LYS B 1 61  ? -45.48591 14.48941  -46.51567 1.000 69.55697  ? 61  LYS B HZ3  1 
ATOM   5531 N N    . SER B 1 62  ? -42.96631 21.29605  -49.59032 1.000 61.42387  ? 62  SER B N    1 
ATOM   5532 C CA   . SER B 1 62  ? -42.39279 22.63073  -49.64760 1.000 72.84007  ? 62  SER B CA   1 
ATOM   5533 C C    . SER B 1 62  ? -41.39383 22.79517  -48.51185 1.000 65.72787  ? 62  SER B C    1 
ATOM   5534 O O    . SER B 1 62  ? -41.38831 22.02667  -47.54741 1.000 68.02845  ? 62  SER B O    1 
ATOM   5535 C CB   . SER B 1 62  ? -43.47036 23.71499  -49.54360 1.000 72.47857  ? 62  SER B CB   1 
ATOM   5536 O OG   . SER B 1 62  ? -44.43533 23.58426  -50.57146 1.000 85.85829  ? 62  SER B OG   1 
ATOM   5537 H H    . SER B 1 62  ? -43.27691 21.09146  -48.81490 1.000 73.70241  ? 62  SER B H    1 
ATOM   5538 H HA   . SER B 1 62  ? -41.92756 22.74410  -50.49117 1.000 87.40186  ? 62  SER B HA   1 
ATOM   5539 H HB2  . SER B 1 62  ? -43.91414 23.63469  -48.68482 1.000 86.96805  ? 62  SER B HB2  1 
ATOM   5540 H HB3  . SER B 1 62  ? -43.04807 24.58500  -49.61876 1.000 86.96805  ? 62  SER B HB3  1 
ATOM   5541 H HG   . SER B 1 62  ? -45.06776 23.09640  -50.31143 1.000 103.02372 ? 62  SER B HG   1 
ATOM   5542 N N    . ASN B 1 63  ? -40.55045 23.82305  -48.62740 1.000 69.40583  ? 63  ASN B N    1 
ATOM   5543 C CA   . ASN B 1 63  ? -39.58485 24.09784  -47.56845 1.000 67.29818  ? 63  ASN B CA   1 
ATOM   5544 C C    . ASN B 1 63  ? -40.26658 24.17656  -46.20694 1.000 68.66776  ? 63  ASN B C    1 
ATOM   5545 O O    . ASN B 1 63  ? -39.73853 23.67196  -45.20891 1.000 69.09097  ? 63  ASN B O    1 
ATOM   5546 C CB   . ASN B 1 63  ? -38.83423 25.39779  -47.86114 1.000 61.26150  ? 63  ASN B CB   1 
ATOM   5547 C CG   . ASN B 1 63  ? -37.97637 25.31087  -49.11149 1.000 70.97249  ? 63  ASN B CG   1 
ATOM   5548 O OD1  . ASN B 1 63  ? -37.63867 24.22054  -49.57530 1.000 66.33912  ? 63  ASN B OD1  1 
ATOM   5549 N ND2  . ASN B 1 63  ? -37.61020 26.46542  -49.65739 1.000 66.14572  ? 63  ASN B ND2  1 
ATOM   5550 H H    . ASN B 1 63  ? -40.51874 24.36405  -49.29517 1.000 83.28076  ? 63  ASN B H    1 
ATOM   5551 H HA   . ASN B 1 63  ? -38.93722 23.37612  -47.54412 1.000 80.75159  ? 63  ASN B HA   1 
ATOM   5552 H HB2  . ASN B 1 63  ? -39.47742 26.11280  -47.98757 1.000 73.50757  ? 63  ASN B HB2  1 
ATOM   5553 H HB3  . ASN B 1 63  ? -38.25307 25.60295  -47.11210 1.000 73.50757  ? 63  ASN B HB3  1 
ATOM   5554 H HD21 . ASN B 1 63  ? -37.12393 26.47063  -50.36669 1.000 79.36864  ? 63  ASN B HD21 1 
ATOM   5555 H HD22 . ASN B 1 63  ? -37.85945 27.20758  -49.30146 1.000 79.36864  ? 63  ASN B HD22 1 
ATOM   5556 N N    . HIS B 1 64  ? -41.45044 24.79472  -46.14874 1.000 63.63992  ? 64  HIS B N    1 
ATOM   5557 C CA   . HIS B 1 64  ? -42.15835 24.95327  -44.88295 1.000 63.25218  ? 64  HIS B CA   1 
ATOM   5558 C C    . HIS B 1 64  ? -42.74994 23.64795  -44.36395 1.000 67.50971  ? 64  HIS B C    1 
ATOM   5559 O O    . HIS B 1 64  ? -43.20752 23.61025  -43.21622 1.000 60.77525  ? 64  HIS B O    1 
ATOM   5560 C CB   . HIS B 1 64  ? -43.26350 26.00871  -45.02357 1.000 68.11623  ? 64  HIS B CB   1 
ATOM   5561 C CG   . HIS B 1 64  ? -44.28064 25.69803  -46.07951 1.000 60.45016  ? 64  HIS B CG   1 
ATOM   5562 N ND1  . HIS B 1 64  ? -44.35021 26.38908  -47.27022 1.000 67.48455  ? 64  HIS B ND1  1 
ATOM   5563 C CD2  . HIS B 1 64  ? -45.27967 24.78420  -46.11708 1.000 64.25001  ? 64  HIS B CD2  1 
ATOM   5564 C CE1  . HIS B 1 64  ? -45.34352 25.91088  -47.99826 1.000 75.93605  ? 64  HIS B CE1  1 
ATOM   5565 N NE2  . HIS B 1 64  ? -45.92138 24.93366  -47.32307 1.000 77.33889  ? 64  HIS B NE2  1 
ATOM   5566 H H    . HIS B 1 64  ? -41.86036 25.12853  -46.82707 1.000 76.36167  ? 64  HIS B H    1 
ATOM   5567 H HA   . HIS B 1 64  ? -41.52807 25.27228  -44.21821 1.000 75.89639  ? 64  HIS B HA   1 
ATOM   5568 H HB2  . HIS B 1 64  ? -43.73154 26.08210  -44.17713 1.000 81.73325  ? 64  HIS B HB2  1 
ATOM   5569 H HB3  . HIS B 1 64  ? -42.85385 26.85807  -45.25088 1.000 81.73325  ? 64  HIS B HB3  1 
ATOM   5570 H HD2  . HIS B 1 64  ? -45.49168 24.17044  -45.45131 1.000 77.09379  ? 64  HIS B HD2  1 
ATOM   5571 H HE1  . HIS B 1 64  ? -45.59333 26.21112  -48.84227 1.000 91.11703  ? 64  HIS B HE1  1 
ATOM   5572 H HE2  . HIS B 1 64  ? -46.59069 24.46665  -47.59423 1.000 92.80043  ? 64  HIS B HE2  1 
ATOM   5573 N N    . ASN B 1 65  ? -42.75840 22.58522  -45.17114 1.000 68.33045  ? 65  ASN B N    1 
ATOM   5574 C CA   . ASN B 1 65  ? -43.17248 21.28177  -44.67006 1.000 65.82298  ? 65  ASN B CA   1 
ATOM   5575 C C    . ASN B 1 65  ? -42.11496 20.64683  -43.77729 1.000 67.09073  ? 65  ASN B C    1 
ATOM   5576 O O    . ASN B 1 65  ? -42.43823 19.73324  -43.01075 1.000 65.48529  ? 65  ASN B O    1 
ATOM   5577 C CB   . ASN B 1 65  ? -43.47238 20.33262  -45.83184 1.000 73.24263  ? 65  ASN B CB   1 
ATOM   5578 C CG   . ASN B 1 65  ? -44.75869 20.67673  -46.55815 1.000 74.19271  ? 65  ASN B CG   1 
ATOM   5579 O OD1  . ASN B 1 65  ? -44.83914 21.67977  -47.26903 1.000 73.75072  ? 65  ASN B OD1  1 
ATOM   5580 N ND2  . ASN B 1 65  ? -45.76672 19.82836  -46.40210 1.000 64.84965  ? 65  ASN B ND2  1 
ATOM   5581 H H    . ASN B 1 65  ? -42.53164 22.59542  -46.00064 1.000 81.99032  ? 65  ASN B H    1 
ATOM   5582 H HA   . ASN B 1 65  ? -43.98570 21.40149  -44.15505 1.000 78.98134  ? 65  ASN B HA   1 
ATOM   5583 H HB2  . ASN B 1 65  ? -42.74545 20.37844  -46.47245 1.000 87.88493  ? 65  ASN B HB2  1 
ATOM   5584 H HB3  . ASN B 1 65  ? -43.55518 19.42937  -45.48806 1.000 87.88493  ? 65  ASN B HB3  1 
ATOM   5585 H HD21 . ASN B 1 65  ? -46.51836 19.97717  -46.79261 1.000 77.81335  ? 65  ASN B HD21 1 
ATOM   5586 H HD22 . ASN B 1 65  ? -45.66850 19.12963  -45.91044 1.000 77.81335  ? 65  ASN B HD22 1 
ATOM   5587 N N    . PHE B 1 66  ? -40.86603 21.10321  -43.86355 1.000 67.42100  ? 66  PHE B N    1 
ATOM   5588 C CA   . PHE B 1 66  ? -39.74679 20.48792  -43.16077 1.000 64.27003  ? 66  PHE B CA   1 
ATOM   5589 C C    . PHE B 1 66  ? -39.41560 21.29482  -41.91225 1.000 53.17164  ? 66  PHE B C    1 
ATOM   5590 O O    . PHE B 1 66  ? -39.02278 22.46236  -42.00817 1.000 68.15514  ? 66  PHE B O    1 
ATOM   5591 C CB   . PHE B 1 66  ? -38.52036 20.39470  -44.06928 1.000 56.04485  ? 66  PHE B CB   1 
ATOM   5592 C CG   . PHE B 1 66  ? -38.73170 19.54330  -45.28514 1.000 50.22230  ? 66  PHE B CG   1 
ATOM   5593 C CD1  . PHE B 1 66  ? -38.71204 18.16247  -45.19115 1.000 43.78016  ? 66  PHE B CD1  1 
ATOM   5594 C CD2  . PHE B 1 66  ? -38.94796 20.12349  -46.52220 1.000 49.20084  ? 66  PHE B CD2  1 
ATOM   5595 C CE1  . PHE B 1 66  ? -38.90724 17.37643  -46.30819 1.000 53.63395  ? 66  PHE B CE1  1 
ATOM   5596 C CE2  . PHE B 1 66  ? -39.14320 19.34305  -47.64379 1.000 63.19124  ? 66  PHE B CE2  1 
ATOM   5597 C CZ   . PHE B 1 66  ? -39.12214 17.96747  -47.53686 1.000 59.05472  ? 66  PHE B CZ   1 
ATOM   5598 H H    . PHE B 1 66  ? -40.63883 21.78531  -44.33549 1.000 80.89898  ? 66  PHE B H    1 
ATOM   5599 H HA   . PHE B 1 66  ? -40.00309 19.59391  -42.88515 1.000 77.11780  ? 66  PHE B HA   1 
ATOM   5600 H HB2  . PHE B 1 66  ? -38.28644 21.28683  -44.36975 1.000 67.24759  ? 66  PHE B HB2  1 
ATOM   5601 H HB3  . PHE B 1 66  ? -37.78635 20.01176  -43.56382 1.000 67.24759  ? 66  PHE B HB3  1 
ATOM   5602 H HD1  . PHE B 1 66  ? -38.56558 17.75993  -44.36567 1.000 52.52997  ? 66  PHE B HD1  1 
ATOM   5603 H HD2  . PHE B 1 66  ? -38.96196 21.05021  -46.59904 1.000 59.03478  ? 66  PHE B HD2  1 
ATOM   5604 H HE1  . PHE B 1 66  ? -38.89404 16.44954  -46.23335 1.000 64.35451  ? 66  PHE B HE1  1 
ATOM   5605 H HE2  . PHE B 1 66  ? -39.28874 19.74372  -48.47035 1.000 75.82326  ? 66  PHE B HE2  1 
ATOM   5606 H HZ   . PHE B 1 66  ? -39.25251 17.43954  -48.29131 1.000 70.85943  ? 66  PHE B HZ   1 
ATOM   5607 N N    . LEU B 1 67  ? -39.55777 20.66488  -40.74954 1.000 50.11668  ? 67  LEU B N    1 
ATOM   5608 C CA   . LEU B 1 67  ? -39.25909 21.28151  -39.46162 1.000 52.15985  ? 67  LEU B CA   1 
ATOM   5609 C C    . LEU B 1 67  ? -37.98479 20.64987  -38.91187 1.000 54.57963  ? 67  LEU B C    1 
ATOM   5610 O O    . LEU B 1 67  ? -37.99155 19.48718  -38.49217 1.000 50.80871  ? 67  LEU B O    1 
ATOM   5611 C CB   . LEU B 1 67  ? -40.42462 21.10267  -38.48970 1.000 52.70005  ? 67  LEU B CB   1 
ATOM   5612 H H    . LEU B 1 67  ? -39.83472 19.85368  -40.67992 1.000 60.13379  ? 67  LEU B H    1 
ATOM   5613 H HA   . LEU B 1 67  ? -39.10431 22.23099  -39.58582 1.000 62.58559  ? 67  LEU B HA   1 
ATOM   5614 N N    . VAL B 1 68  ? -36.89677 21.41277  -38.91259 1.000 52.51920  ? 68  VAL B N    1 
ATOM   5615 C CA   . VAL B 1 68  ? -35.61756 20.95547  -38.38543 1.000 51.93659  ? 68  VAL B CA   1 
ATOM   5616 C C    . VAL B 1 68  ? -35.42134 21.57826  -37.01200 1.000 48.85607  ? 68  VAL B C    1 
ATOM   5617 O O    . VAL B 1 68  ? -35.41496 22.80721  -36.87273 1.000 54.65583  ? 68  VAL B O    1 
ATOM   5618 C CB   . VAL B 1 68  ? -34.45607 21.31792  -39.32284 1.000 52.87608  ? 68  VAL B CB   1 
ATOM   5619 C CG1  . VAL B 1 68  ? -33.13119 20.95470  -38.67370 1.000 42.71824  ? 68  VAL B CG1  1 
ATOM   5620 C CG2  . VAL B 1 68  ? -34.60749 20.60349  -40.65905 1.000 58.93290  ? 68  VAL B CG2  1 
ATOM   5621 H H    . VAL B 1 68  ? -36.87528 22.21574  -39.21979 1.000 63.01681  ? 68  VAL B H    1 
ATOM   5622 H HA   . VAL B 1 68  ? -35.64138 19.99070  -38.28774 1.000 62.31768  ? 68  VAL B HA   1 
ATOM   5623 H HB   . VAL B 1 68  ? -34.46734 22.27355  -39.48876 1.000 63.44507  ? 68  VAL B HB   1 
ATOM   5624 H HG11 . VAL B 1 68  ? -33.23750 20.12572  -38.18137 1.000 51.25566  ? 68  VAL B HG11 1 
ATOM   5625 H HG12 . VAL B 1 68  ? -32.46018 20.84485  -39.36549 1.000 51.25566  ? 68  VAL B HG12 1 
ATOM   5626 H HG13 . VAL B 1 68  ? -32.86978 21.66707  -38.06946 1.000 51.25566  ? 68  VAL B HG13 1 
ATOM   5627 H HG21 . VAL B 1 68  ? -33.91973 20.91938  -41.26577 1.000 70.71325  ? 68  VAL B HG21 1 
ATOM   5628 H HG22 . VAL B 1 68  ? -34.51191 19.64841  -40.51913 1.000 70.71325  ? 68  VAL B HG22 1 
ATOM   5629 H HG23 . VAL B 1 68  ? -35.48504 20.79821  -41.02360 1.000 70.71325  ? 68  VAL B HG23 1 
ATOM   5630 N N    . GLN B 1 69  ? -35.26602 20.73418  -35.99832 1.000 43.37744  ? 69  GLN B N    1 
ATOM   5631 C CA   . GLN B 1 69  ? -34.96285 21.17495  -34.64509 1.000 49.27509  ? 69  GLN B CA   1 
ATOM   5632 C C    . GLN B 1 69  ? -33.55315 20.72644  -34.28732 1.000 51.09633  ? 69  GLN B C    1 
ATOM   5633 O O    . GLN B 1 69  ? -33.18276 19.57177  -34.52490 1.000 47.81679  ? 69  GLN B O    1 
ATOM   5634 C CB   . GLN B 1 69  ? -35.97691 20.62183  -33.64374 1.000 63.04181  ? 69  GLN B CB   1 
ATOM   5635 C CG   . GLN B 1 69  ? -37.41780 20.94277  -34.00289 1.000 72.07466  ? 69  GLN B CG   1 
ATOM   5636 C CD   . GLN B 1 69  ? -38.34153 20.86867  -32.80878 1.000 75.58742  ? 69  GLN B CD   1 
ATOM   5637 O OE1  . GLN B 1 69  ? -37.99048 20.30322  -31.77390 1.000 81.42172  ? 69  GLN B OE1  1 
ATOM   5638 N NE2  . GLN B 1 69  ? -39.52901 21.44683  -32.94212 1.000 82.63963  ? 69  GLN B NE2  1 
ATOM   5639 H H    . GLN B 1 69  ? -35.33354 19.88013  -36.07339 1.000 52.04670  ? 69  GLN B H    1 
ATOM   5640 H HA   . GLN B 1 69  ? -34.99991 22.14303  -34.59646 1.000 59.12388  ? 69  GLN B HA   1 
ATOM   5641 H HB2  . GLN B 1 69  ? -35.88712 19.65665  -33.60810 1.000 75.64394  ? 69  GLN B HB2  1 
ATOM   5642 H HB3  . GLN B 1 69  ? -35.79560 21.00434  -32.77098 1.000 75.64394  ? 69  GLN B HB3  1 
ATOM   5643 H HG2  . GLN B 1 69  ? -37.46213 21.84258  -34.36245 1.000 86.48336  ? 69  GLN B HG2  1 
ATOM   5644 H HG3  . GLN B 1 69  ? -37.72924 20.30542  -34.66447 1.000 86.48336  ? 69  GLN B HG3  1 
ATOM   5645 H HE21 . GLN B 1 69  ? -40.09022 21.43168  -32.29066 1.000 99.16133  ? 69  GLN B HE21 1 
ATOM   5646 H HE22 . GLN B 1 69  ? -39.73710 21.83654  -33.67997 1.000 99.16133  ? 69  GLN B HE22 1 
ATOM   5647 N N    . ALA B 1 70  ? -32.76831 21.64804  -33.74072 1.000 55.05285  ? 70  ALA B N    1 
ATOM   5648 C CA   . ALA B 1 70  ? -31.38234 21.40273  -33.34892 1.000 55.05964  ? 70  ALA B CA   1 
ATOM   5649 C C    . ALA B 1 70  ? -31.30933 21.69365  -31.85492 1.000 56.77617  ? 70  ALA B C    1 
ATOM   5650 O O    . ALA B 1 70  ? -31.26846 22.85689  -31.44183 1.000 59.53451  ? 70  ALA B O    1 
ATOM   5651 C CB   . ALA B 1 70  ? -30.41961 22.27049  -34.15038 1.000 49.76317  ? 70  ALA B CB   1 
ATOM   5652 H H    . ALA B 1 70  ? -33.02468 22.45316  -33.58056 1.000 66.05720  ? 70  ALA B H    1 
ATOM   5653 H HA   . ALA B 1 70  ? -31.13801 20.47796  -33.51021 1.000 66.06534  ? 70  ALA B HA   1 
ATOM   5654 H HB1  . ALA B 1 70  ? -30.59844 22.15000  -35.09611 1.000 59.70957  ? 70  ALA B HB1  1 
ATOM   5655 H HB2  . ALA B 1 70  ? -30.55221 23.19937  -33.90439 1.000 59.70957  ? 70  ALA B HB2  1 
ATOM   5656 H HB3  . ALA B 1 70  ? -29.50966 22.00161  -33.94891 1.000 59.70957  ? 70  ALA B HB3  1 
ATOM   5657 N N    . GLY B 1 71  ? -31.29698 20.64220  -31.04720 1.000 57.56381  ? 71  GLY B N    1 
ATOM   5658 C CA   . GLY B 1 71  ? -31.59841 20.83199  -29.64108 1.000 63.64599  ? 71  GLY B CA   1 
ATOM   5659 C C    . GLY B 1 71  ? -33.00661 21.37753  -29.52796 1.000 65.89741  ? 71  GLY B C    1 
ATOM   5660 O O    . GLY B 1 71  ? -33.95401 20.83421  -30.10675 1.000 86.17630  ? 71  GLY B O    1 
ATOM   5661 H H    . GLY B 1 71  ? -31.12246 19.83346  -31.28188 1.000 69.07034  ? 71  GLY B H    1 
ATOM   5662 H HA2  . GLY B 1 71  ? -31.54010 19.98801  -29.16653 1.000 76.36895  ? 71  GLY B HA2  1 
ATOM   5663 H HA3  . GLY B 1 71  ? -30.97569 21.46105  -29.24435 1.000 76.36895  ? 71  GLY B HA3  1 
ATOM   5664 N N    . ASN B 1 72  ? -33.15751 22.47665  -28.79095 1.000 74.31717  ? 72  ASN B N    1 
ATOM   5665 C CA   . ASN B 1 72  ? -34.44883 23.15092  -28.73658 1.000 69.50036  ? 72  ASN B CA   1 
ATOM   5666 C C    . ASN B 1 72  ? -34.69982 23.95997  -30.00600 1.000 76.46454  ? 72  ASN B C    1 
ATOM   5667 O O    . ASN B 1 72  ? -35.77518 23.87124  -30.60883 1.000 90.24963  ? 72  ASN B O    1 
ATOM   5668 C CB   . ASN B 1 72  ? -34.51207 24.06015  -27.50671 1.000 83.39207  ? 72  ASN B CB   1 
ATOM   5669 C CG   . ASN B 1 72  ? -33.50754 25.20211  -27.57181 1.000 91.23079  ? 72  ASN B CG   1 
ATOM   5670 O OD1  . ASN B 1 72  ? -32.55724 25.16158  -28.35489 1.000 87.11650  ? 72  ASN B OD1  1 
ATOM   5671 N ND2  . ASN B 1 72  ? -33.71597 26.22724  -26.75018 1.000 93.01688  ? 72  ASN B ND2  1 
ATOM   5672 H H    . ASN B 1 72  ? -32.53800 22.84490  -28.32170 1.000 89.17437  ? 72  ASN B H    1 
ATOM   5673 H HA   . ASN B 1 72  ? -35.14855 22.48391  -28.65658 1.000 83.39420  ? 72  ASN B HA   1 
ATOM   5674 H HB2  . ASN B 1 72  ? -35.40038 24.44439  -27.44216 1.000 100.06426 ? 72  ASN B HB2  1 
ATOM   5675 H HB3  . ASN B 1 72  ? -34.31938 23.53498  -26.71427 1.000 100.06426 ? 72  ASN B HB3  1 
ATOM   5676 H HD21 . ASN B 1 72  ? -33.17501 26.89580  -26.75092 1.000 111.61403 ? 72  ASN B HD21 1 
ATOM   5677 H HD22 . ASN B 1 72  ? -34.39169 26.22146  -26.21823 1.000 111.61403 ? 72  ASN B HD22 1 
ATOM   5678 N N    . VAL B 1 73  ? -33.70137 24.73402  -30.43585 1.000 65.53406  ? 73  VAL B N    1 
ATOM   5679 C CA   . VAL B 1 73  ? -33.92482 25.75670  -31.44876 1.000 68.14900  ? 73  VAL B CA   1 
ATOM   5680 C C    . VAL B 1 73  ? -34.34849 25.12199  -32.76344 1.000 60.91412  ? 73  VAL B C    1 
ATOM   5681 O O    . VAL B 1 73  ? -33.73737 24.15607  -33.23759 1.000 61.25642  ? 73  VAL B O    1 
ATOM   5682 C CB   . VAL B 1 73  ? -32.65661 26.60511  -31.62649 1.000 66.65724  ? 73  VAL B CB   1 
ATOM   5683 C CG1  . VAL B 1 73  ? -32.85122 27.62005  -32.74965 1.000 68.82085  ? 73  VAL B CG1  1 
ATOM   5684 C CG2  . VAL B 1 73  ? -32.29357 27.29092  -30.31327 1.000 61.35648  ? 73  VAL B CG2  1 
ATOM   5685 H H    . VAL B 1 73  ? -32.88955 24.68510  -30.15630 1.000 78.63464  ? 73  VAL B H    1 
ATOM   5686 H HA   . VAL B 1 73  ? -34.64943 26.32845  -31.15052 1.000 81.77258  ? 73  VAL B HA   1 
ATOM   5687 H HB   . VAL B 1 73  ? -31.91545 26.03075  -31.87486 1.000 79.98246  ? 73  VAL B HB   1 
ATOM   5688 H HG11 . VAL B 1 73  ? -33.77362 27.92016  -32.74777 1.000 82.57879  ? 73  VAL B HG11 1 
ATOM   5689 H HG12 . VAL B 1 73  ? -32.25808 28.37306  -32.60111 1.000 82.57879  ? 73  VAL B HG12 1 
ATOM   5690 H HG13 . VAL B 1 73  ? -32.64276 27.19694  -33.59725 1.000 82.57879  ? 73  VAL B HG13 1 
ATOM   5691 H HG21 . VAL B 1 73  ? -33.04340 27.21983  -29.70204 1.000 73.62155  ? 73  VAL B HG21 1 
ATOM   5692 H HG22 . VAL B 1 73  ? -31.51491 26.85440  -29.93375 1.000 73.62155  ? 73  VAL B HG22 1 
ATOM   5693 H HG23 . VAL B 1 73  ? -32.09691 28.22450  -30.48837 1.000 73.62155  ? 73  VAL B HG23 1 
ATOM   5694 N N    . GLN B 1 74  ? -35.39890 25.67477  -33.36437 1.000 63.78918  ? 74  GLN B N    1 
ATOM   5695 C CA   . GLN B 1 74  ? -35.82596 25.25855  -34.69058 1.000 56.22314  ? 74  GLN B CA   1 
ATOM   5696 C C    . GLN B 1 74  ? -35.02738 26.00791  -35.74771 1.000 58.30360  ? 74  GLN B C    1 
ATOM   5697 O O    . GLN B 1 74  ? -34.79651 27.21485  -35.63113 1.000 61.75817  ? 74  GLN B O    1 
ATOM   5698 C CB   . GLN B 1 74  ? -37.31991 25.52054  -34.87866 1.000 52.66783  ? 74  GLN B CB   1 
ATOM   5699 H H    . GLN B 1 74  ? -35.88269 26.29709  -33.02046 1.000 76.54079  ? 74  GLN B H    1 
ATOM   5700 H HA   . GLN B 1 74  ? -35.67443 24.30691  -34.80154 1.000 67.46155  ? 74  GLN B HA   1 
ATOM   5701 N N    . LEU B 1 75  ? -34.59207 25.28200  -36.77283 1.000 59.06664  ? 75  LEU B N    1 
ATOM   5702 C CA   . LEU B 1 75  ? -33.87672 25.86391  -37.89794 1.000 63.60209  ? 75  LEU B CA   1 
ATOM   5703 C C    . LEU B 1 75  ? -34.85156 26.16893  -39.02883 1.000 70.95648  ? 75  LEU B C    1 
ATOM   5704 O O    . LEU B 1 75  ? -35.90836 25.54273  -39.14832 1.000 69.95400  ? 75  LEU B O    1 
ATOM   5705 C CB   . LEU B 1 75  ? -32.77941 24.92560  -38.40639 1.000 60.63148  ? 75  LEU B CB   1 
ATOM   5706 C CG   . LEU B 1 75  ? -31.52340 24.73444  -37.55007 1.000 64.51892  ? 75  LEU B CG   1 
ATOM   5707 C CD1  . LEU B 1 75  ? -30.54076 23.80552  -38.26878 1.000 54.37901  ? 75  LEU B CD1  1 
ATOM   5708 C CD2  . LEU B 1 75  ? -30.85279 26.06371  -37.21640 1.000 56.17942  ? 75  LEU B CD2  1 
ATOM   5709 H H    . LEU B 1 75  ? -34.70259 24.43168  -36.83870 1.000 70.87374  ? 75  LEU B H    1 
ATOM   5710 H HA   . LEU B 1 75  ? -33.45406 26.68991  -37.61512 1.000 76.31628  ? 75  LEU B HA   1 
ATOM   5711 H HB2  . LEU B 1 75  ? -33.17458 24.04664  -38.51672 1.000 72.75155  ? 75  LEU B HB2  1 
ATOM   5712 H HB3  . LEU B 1 75  ? -32.47952 25.26458  -39.26432 1.000 72.75155  ? 75  LEU B HB3  1 
ATOM   5713 H HG   . LEU B 1 75  ? -31.78489 24.33080  -36.70769 1.000 77.41648  ? 75  LEU B HG   1 
ATOM   5714 H HD11 . LEU B 1 75  ? -30.99821 22.98323  -38.50431 1.000 65.24859  ? 75  LEU B HD11 1 
ATOM   5715 H HD12 . LEU B 1 75  ? -30.21855 24.24613  -39.07061 1.000 65.24859  ? 75  LEU B HD12 1 
ATOM   5716 H HD13 . LEU B 1 75  ? -29.79757 23.61248  -37.67606 1.000 65.24859  ? 75  LEU B HD13 1 
ATOM   5717 H HD21 . LEU B 1 75  ? -30.66412 26.53805  -38.04120 1.000 67.40908  ? 75  LEU B HD21 1 
ATOM   5718 H HD22 . LEU B 1 75  ? -31.45106 26.58891  -36.66220 1.000 67.40908  ? 75  LEU B HD22 1 
ATOM   5719 H HD23 . LEU B 1 75  ? -30.02679 25.88955  -36.73860 1.000 67.40908  ? 75  LEU B HD23 1 
ATOM   5720 N N    . ARG B 1 76  ? -34.48307 27.13761  -39.86289 1.000 65.80341  ? 76  ARG B N    1 
ATOM   5721 C CA   . ARG B 1 76  ? -35.30847 27.56078  -40.98673 1.000 65.06252  ? 76  ARG B CA   1 
ATOM   5722 C C    . ARG B 1 76  ? -34.78249 26.92029  -42.26562 1.000 60.31764  ? 76  ARG B C    1 
ATOM   5723 O O    . ARG B 1 76  ? -33.63247 27.15259  -42.65402 1.000 53.86401  ? 76  ARG B O    1 
ATOM   5724 C CB   . ARG B 1 76  ? -35.31756 29.08370  -41.12111 1.000 66.68748  ? 76  ARG B CB   1 
ATOM   5725 C CG   . ARG B 1 76  ? -36.26852 29.60300  -42.19692 1.000 73.68626  ? 76  ARG B CG   1 
ATOM   5726 C CD   . ARG B 1 76  ? -35.95292 31.04389  -42.58268 1.000 72.76548  ? 76  ARG B CD   1 
ATOM   5727 N NE   . ARG B 1 76  ? -36.00009 31.93974  -41.43316 1.000 81.48655  ? 76  ARG B NE   1 
ATOM   5728 C CZ   . ARG B 1 76  ? -37.11918 32.38452  -40.87779 1.000 75.93941  ? 76  ARG B CZ   1 
ATOM   5729 N NH1  . ARG B 1 76  ? -38.30762 32.02925  -41.33738 1.000 72.03413  ? 76  ARG B NH1  1 
ATOM   5730 N NH2  . ARG B 1 76  ? -37.04453 33.20016  -39.83023 1.000 76.93626  ? 76  ARG B NH2  1 
ATOM   5731 H H    . ARG B 1 76  ? -33.74410 27.57235  -39.79558 1.000 78.95786  ? 76  ARG B H    1 
ATOM   5732 H HA   . ARG B 1 76  ? -36.21913 27.26003  -40.84133 1.000 78.06880  ? 76  ARG B HA   1 
ATOM   5733 H HB2  . ARG B 1 76  ? -35.59044 29.46945  -40.27398 1.000 80.01875  ? 76  ARG B HB2  1 
ATOM   5734 H HB3  . ARG B 1 76  ? -34.42287 29.38160  -41.34845 1.000 80.01875  ? 76  ARG B HB3  1 
ATOM   5735 H HG2  . ARG B 1 76  ? -36.18644 29.05118  -42.99044 1.000 88.41728  ? 76  ARG B HG2  1 
ATOM   5736 H HG3  . ARG B 1 76  ? -37.17858 29.57038  -41.86282 1.000 88.41728  ? 76  ARG B HG3  1 
ATOM   5737 H HD2  . ARG B 1 76  ? -35.06120 31.08473  -42.96226 1.000 87.31234  ? 76  ARG B HD2  1 
ATOM   5738 H HD3  . ARG B 1 76  ? -36.60449 31.35038  -43.23262 1.000 87.31234  ? 76  ARG B HD3  1 
ATOM   5739 H HE   . ARG B 1 76  ? -35.25313 32.19653  -41.09301 1.000 97.77763  ? 76  ARG B HE   1 
ATOM   5740 H HH11 . ARG B 1 76  ? -38.36691 31.49818  -42.01121 1.000 86.43473  ? 76  ARG B HH11 1 
ATOM   5741 H HH12 . ARG B 1 76  ? -39.02098 32.32935  -40.96234 1.000 86.43473  ? 76  ARG B HH12 1 
ATOM   5742 H HH21 . ARG B 1 76  ? -36.27681 33.43328  -39.52061 1.000 92.31728  ? 76  ARG B HH21 1 
ATOM   5743 H HH22 . ARG B 1 76  ? -37.76397 33.49455  -39.46235 1.000 92.31728  ? 76  ARG B HH22 1 
ATOM   5744 N N    . VAL B 1 77  ? -35.63007 26.13276  -42.91990 1.000 59.65700  ? 77  VAL B N    1 
ATOM   5745 C CA   . VAL B 1 77  ? -35.28995 25.47452  -44.17658 1.000 59.48052  ? 77  VAL B CA   1 
ATOM   5746 C C    . VAL B 1 77  ? -35.57249 26.44175  -45.31909 1.000 55.21853  ? 77  VAL B C    1 
ATOM   5747 O O    . VAL B 1 77  ? -36.68041 26.98015  -45.42727 1.000 67.50872  ? 77  VAL B O    1 
ATOM   5748 C CB   . VAL B 1 77  ? -36.08913 24.16978  -44.34061 1.000 58.81763  ? 77  VAL B CB   1 
ATOM   5749 C CG1  . VAL B 1 77  ? -35.73065 23.47215  -45.64416 1.000 55.90304  ? 77  VAL B CG1  1 
ATOM   5750 C CG2  . VAL B 1 77  ? -35.85004 23.24699  -43.14562 1.000 56.58528  ? 77  VAL B CG2  1 
ATOM   5751 H H    . VAL B 1 77  ? -36.42790 25.95988  -42.64939 1.000 71.58217  ? 77  VAL B H    1 
ATOM   5752 H HA   . VAL B 1 77  ? -34.34490 25.25616  -44.18678 1.000 71.37040  ? 77  VAL B HA   1 
ATOM   5753 H HB   . VAL B 1 77  ? -37.03432 24.38523  -44.37388 1.000 70.57493  ? 77  VAL B HB   1 
ATOM   5754 H HG11 . VAL B 1 77  ? -34.94507 23.89616  -46.02360 1.000 67.07742  ? 77  VAL B HG11 1 
ATOM   5755 H HG12 . VAL B 1 77  ? -35.54649 22.53741  -45.46182 1.000 67.07742  ? 77  VAL B HG12 1 
ATOM   5756 H HG13 . VAL B 1 77  ? -36.47714 23.54844  -46.25883 1.000 67.07742  ? 77  VAL B HG13 1 
ATOM   5757 H HG21 . VAL B 1 77  ? -36.34796 22.42494  -43.27682 1.000 67.89610  ? 77  VAL B HG21 1 
ATOM   5758 H HG22 . VAL B 1 77  ? -34.90187 23.05273  -43.08136 1.000 67.89610  ? 77  VAL B HG22 1 
ATOM   5759 H HG23 . VAL B 1 77  ? -36.15212 23.69138  -42.33804 1.000 67.89610  ? 77  VAL B HG23 1 
ATOM   5760 N N    . ILE B 1 78  ? -34.57415 26.65948  -46.17742 1.000 54.65057  ? 78  ILE B N    1 
ATOM   5761 C CA   . ILE B 1 78  ? -34.67071 27.66275  -47.23367 1.000 54.50626  ? 78  ILE B CA   1 
ATOM   5762 C C    . ILE B 1 78  ? -34.29205 27.05940  -48.58025 1.000 64.75759  ? 78  ILE B C    1 
ATOM   5763 O O    . ILE B 1 78  ? -33.77754 27.75681  -49.46285 1.000 55.71841  ? 78  ILE B O    1 
ATOM   5764 C CB   . ILE B 1 78  ? -33.77947 28.87847  -46.91454 1.000 50.85247  ? 78  ILE B CB   1 
ATOM   5765 C CG1  . ILE B 1 78  ? -32.30900 28.45603  -46.83212 1.000 55.59118  ? 78  ILE B CG1  1 
ATOM   5766 C CG2  . ILE B 1 78  ? -34.22259 29.52120  -45.60544 1.000 58.84223  ? 78  ILE B CG2  1 
ATOM   5767 C CD1  . ILE B 1 78  ? -31.32841 29.61500  -46.83865 1.000 48.88139  ? 78  ILE B CD1  1 
ATOM   5768 H H    . ILE B 1 78  ? -33.82628 26.23499  -46.16689 1.000 65.57445  ? 78  ILE B H    1 
ATOM   5769 H HA   . ILE B 1 78  ? -35.59482 27.95138  -47.29370 1.000 65.40128  ? 78  ILE B HA   1 
ATOM   5770 H HB   . ILE B 1 78  ? -33.87220 29.52676  -47.63009 1.000 61.01673  ? 78  ILE B HB   1 
ATOM   5771 H HG12 . ILE B 1 78  ? -32.17402 27.96088  -46.00901 1.000 66.70319  ? 78  ILE B HG12 1 
ATOM   5772 H HG13 . ILE B 1 78  ? -32.10457 27.89317  -47.59520 1.000 66.70319  ? 78  ILE B HG13 1 
ATOM   5773 H HG21 . ILE B 1 78  ? -34.21482 28.84974  -44.90545 1.000 70.60445  ? 78  ILE B HG21 1 
ATOM   5774 H HG22 . ILE B 1 78  ? -33.60914 30.23870  -45.38236 1.000 70.60445  ? 78  ILE B HG22 1 
ATOM   5775 H HG23 . ILE B 1 78  ? -35.11926 29.87465  -45.71480 1.000 70.60445  ? 78  ILE B HG23 1 
ATOM   5776 H HD11 . ILE B 1 78  ? -31.08761 29.81976  -47.75571 1.000 58.65144  ? 78  ILE B HD11 1 
ATOM   5777 H HD12 . ILE B 1 78  ? -31.74836 30.38631  -46.42682 1.000 58.65144  ? 78  ILE B HD12 1 
ATOM   5778 H HD13 . ILE B 1 78  ? -30.53732 29.36216  -46.33751 1.000 58.65144  ? 78  ILE B HD13 1 
ATOM   5779 N N    . GLY B 1 79  ? -34.54921 25.76546  -48.74922 1.000 62.26208  ? 79  GLY B N    1 
ATOM   5780 C CA   . GLY B 1 79  ? -34.17404 25.07024  -49.96403 1.000 64.96508  ? 79  GLY B CA   1 
ATOM   5781 C C    . GLY B 1 79  ? -34.07587 23.57422  -49.75434 1.000 62.07975  ? 79  GLY B C    1 
ATOM   5782 O O    . GLY B 1 79  ? -33.70390 23.11929  -48.66790 1.000 52.64136  ? 79  GLY B O    1 
ATOM   5783 H H    . GLY B 1 79  ? -34.94297 25.26853  -48.16816 1.000 74.70827  ? 79  GLY B H    1 
ATOM   5784 H HA2  . GLY B 1 79  ? -34.83683 25.24156  -50.65124 1.000 77.95187  ? 79  GLY B HA2  1 
ATOM   5785 H HA3  . GLY B 1 79  ? -33.31228 25.39526  -50.26838 1.000 77.95187  ? 79  GLY B HA3  1 
ATOM   5786 N N    . HIS B 1 80  ? -34.41878 22.79530  -50.77805 1.000 59.74581  ? 80  HIS B N    1 
ATOM   5787 C CA   . HIS B 1 80  ? -34.35043 21.34574  -50.67674 1.000 48.48321  ? 80  HIS B CA   1 
ATOM   5788 C C    . HIS B 1 80  ? -34.05294 20.75344  -52.04490 1.000 52.60740  ? 80  HIS B C    1 
ATOM   5789 O O    . HIS B 1 80  ? -34.51327 21.26586  -53.06820 1.000 55.32341  ? 80  HIS B O    1 
ATOM   5790 C CB   . HIS B 1 80  ? -35.65169 20.75472  -50.10891 1.000 47.61410  ? 80  HIS B CB   1 
ATOM   5791 C CG   . HIS B 1 80  ? -36.82333 20.82674  -51.04206 1.000 62.42710  ? 80  HIS B CG   1 
ATOM   5792 N ND1  . HIS B 1 80  ? -37.91232 21.63902  -50.80698 1.000 67.02614  ? 80  HIS B ND1  1 
ATOM   5793 C CD2  . HIS B 1 80  ? -37.09103 20.16506  -52.19357 1.000 54.68838  ? 80  HIS B CD2  1 
ATOM   5794 C CE1  . HIS B 1 80  ? -38.79163 21.48755  -51.78153 1.000 62.77205  ? 80  HIS B CE1  1 
ATOM   5795 N NE2  . HIS B 1 80  ? -38.31622 20.60066  -52.63718 1.000 66.21936  ? 80  HIS B NE2  1 
ATOM   5796 H H    . HIS B 1 80  ? -34.69353 23.08500  -51.53975 1.000 71.68875  ? 80  HIS B H    1 
ATOM   5797 H HA   . HIS B 1 80  ? -33.62294 21.10304  -50.08280 1.000 58.17362  ? 80  HIS B HA   1 
ATOM   5798 H HB2  . HIS B 1 80  ? -35.50106 19.81982  -49.89876 1.000 57.13069  ? 80  HIS B HB2  1 
ATOM   5799 H HB3  . HIS B 1 80  ? -35.88740 21.24191  -49.30393 1.000 57.13069  ? 80  HIS B HB3  1 
ATOM   5800 H HD1  . HIS B 1 80  ? -38.00486 22.16278  -50.13118 1.000 80.42514  ? 80  HIS B HD1  1 
ATOM   5801 H HD2  . HIS B 1 80  ? -36.54705 19.53388  -52.60660 1.000 65.61983  ? 80  HIS B HD2  1 
ATOM   5802 H HE1  . HIS B 1 80  ? -39.60650 21.93005  -51.85288 1.000 75.32024  ? 80  HIS B HE1  1 
ATOM   5803 N N    . SER B 1 81  ? -33.27020 19.67763  -52.04858 1.000 50.02065  ? 81  SER B N    1 
ATOM   5804 C CA   . SER B 1 81  ? -33.01642 18.90694  -53.25461 1.000 44.56715  ? 81  SER B CA   1 
ATOM   5805 C C    . SER B 1 81  ? -32.84113 17.45036  -52.85577 1.000 48.58467  ? 81  SER B C    1 
ATOM   5806 O O    . SER B 1 81  ? -32.61356 17.12887  -51.68620 1.000 49.26312  ? 81  SER B O    1 
ATOM   5807 C CB   . SER B 1 81  ? -31.78344 19.41493  -54.01027 1.000 41.91401  ? 81  SER B CB   1 
ATOM   5808 O OG   . SER B 1 81  ? -30.59997 19.19782  -53.26431 1.000 59.62547  ? 81  SER B OG   1 
ATOM   5809 H H    . SER B 1 81  ? -32.86928 19.37107  -51.35224 1.000 60.01855  ? 81  SER B H    1 
ATOM   5810 H HA   . SER B 1 81  ? -33.77552 18.97774  -53.85432 1.000 53.47435  ? 81  SER B HA   1 
ATOM   5811 H HB2  . SER B 1 81  ? -31.71457 18.94112  -54.85387 1.000 50.29058  ? 81  SER B HB2  1 
ATOM   5812 H HB3  . SER B 1 81  ? -31.88338 20.36625  -54.17127 1.000 50.29058  ? 81  SER B HB3  1 
ATOM   5813 H HG   . SER B 1 81  ? -30.66435 19.56308  -52.51063 1.000 71.54433  ? 81  SER B HG   1 
ATOM   5814 N N    . MET B 1 82  ? -32.95829 16.56879  -53.84288 1.000 43.08431  ? 82  MET B N    1 
ATOM   5815 C CA   . MET B 1 82  ? -32.83496 15.13347  -53.63116 1.000 41.44687  ? 82  MET B CA   1 
ATOM   5816 C C    . MET B 1 82  ? -31.62979 14.63247  -54.41063 1.000 40.15517  ? 82  MET B C    1 
ATOM   5817 O O    . MET B 1 82  ? -31.60420 14.72238  -55.64266 1.000 43.08928  ? 82  MET B O    1 
ATOM   5818 C CB   . MET B 1 82  ? -34.10445 14.39950  -54.06723 1.000 40.35881  ? 82  MET B CB   1 
ATOM   5819 C CG   . MET B 1 82  ? -34.05877 12.90184  -53.79333 1.000 45.88966  ? 82  MET B CG   1 
ATOM   5820 S SD   . MET B 1 82  ? -35.61494 12.03959  -54.08187 1.000 44.68052  ? 82  MET B SD   1 
ATOM   5821 C CE   . MET B 1 82  ? -36.04879 12.65690  -55.70502 1.000 40.43615  ? 82  MET B CE   1 
ATOM   5822 H H    . MET B 1 82  ? -33.11259 16.78414  -54.66106 1.000 51.69494  ? 82  MET B H    1 
ATOM   5823 H HA   . MET B 1 82  ? -32.70023 14.95921  -52.68650 1.000 49.73001  ? 82  MET B HA   1 
ATOM   5824 H HB2  . MET B 1 82  ? -34.86102 14.76782  -53.58468 1.000 48.42434  ? 82  MET B HB2  1 
ATOM   5825 H HB3  . MET B 1 82  ? -34.22681 14.52443  -55.02133 1.000 48.42434  ? 82  MET B HB3  1 
ATOM   5826 H HG2  . MET B 1 82  ? -33.39131 12.50192  -54.37252 1.000 55.06136  ? 82  MET B HG2  1 
ATOM   5827 H HG3  . MET B 1 82  ? -33.81666 12.76481  -52.86408 1.000 55.06136  ? 82  MET B HG3  1 
ATOM   5828 H HE1  . MET B 1 82  ? -35.23908 12.76811  -56.22741 1.000 48.51715  ? 82  MET B HE1  1 
ATOM   5829 H HE2  . MET B 1 82  ? -36.63716 12.01912  -56.13856 1.000 48.51715  ? 82  MET B HE2  1 
ATOM   5830 H HE3  . MET B 1 82  ? -36.49978 13.51021  -55.60820 1.000 48.51715  ? 82  MET B HE3  1 
ATOM   5831 N N    . GLN B 1 83  ? -30.63159 14.12390  -53.69284 1.000 36.07393  ? 83  GLN B N    1 
ATOM   5832 C CA   . GLN B 1 83  ? -29.45521 13.50144  -54.29400 1.000 38.31534  ? 83  GLN B CA   1 
ATOM   5833 C C    . GLN B 1 83  ? -29.55723 12.00125  -54.04499 1.000 33.81363  ? 83  GLN B C    1 
ATOM   5834 O O    . GLN B 1 83  ? -29.30357 11.53172  -52.93330 1.000 36.82441  ? 83  GLN B O    1 
ATOM   5835 C CB   . GLN B 1 83  ? -28.16542 14.06687  -53.71195 1.000 46.01182  ? 83  GLN B CB   1 
ATOM   5836 C CG   . GLN B 1 83  ? -26.92089 13.55916  -54.41582 1.000 40.77526  ? 83  GLN B CG   1 
ATOM   5837 C CD   . GLN B 1 83  ? -25.64778 14.18723  -53.88132 1.000 48.76600  ? 83  GLN B CD   1 
ATOM   5838 O OE1  . GLN B 1 83  ? -25.68632 15.03643  -52.99127 1.000 43.67766  ? 83  GLN B OE1  1 
ATOM   5839 N NE2  . GLN B 1 83  ? -24.50867 13.77291  -54.42807 1.000 55.00901  ? 83  GLN B NE2  1 
ATOM   5840 H H    . GLN B 1 83  ? -30.61307 14.12798  -52.83305 1.000 43.28249  ? 83  GLN B H    1 
ATOM   5841 H HA   . GLN B 1 83  ? -29.45620 13.67160  -55.24895 1.000 45.97218  ? 83  GLN B HA   1 
ATOM   5842 H HB2  . GLN B 1 83  ? -28.18129 15.03334  -53.79309 1.000 55.20796  ? 83  GLN B HB2  1 
ATOM   5843 H HB3  . GLN B 1 83  ? -28.10469 13.81334  -52.77764 1.000 55.20796  ? 83  GLN B HB3  1 
ATOM   5844 H HG2  . GLN B 1 83  ? -26.85688 12.59925  -54.29185 1.000 48.92409  ? 83  GLN B HG2  1 
ATOM   5845 H HG3  . GLN B 1 83  ? -26.98468 13.76809  -55.36091 1.000 48.92409  ? 83  GLN B HG3  1 
ATOM   5846 H HE21 . GLN B 1 83  ? -24.52123 13.17922  -55.05014 1.000 66.00459  ? 83  GLN B HE21 1 
ATOM   5847 H HE22 . GLN B 1 83  ? -23.75938 14.09863  -54.15960 1.000 66.00459  ? 83  GLN B HE22 1 
ATOM   5848 N N    . ASN B 1 84  ? -29.92085 11.25291  -55.08605 1.000 34.72010  ? 84  ASN B N    1 
ATOM   5849 C CA   . ASN B 1 84  ? -30.14964 9.82005   -54.94516 1.000 33.77121  ? 84  ASN B CA   1 
ATOM   5850 C C    . ASN B 1 84  ? -31.13757 9.57345   -53.80755 1.000 42.44356  ? 84  ASN B C    1 
ATOM   5851 O O    . ASN B 1 84  ? -32.28979 10.01404  -53.88575 1.000 31.47358  ? 84  ASN B O    1 
ATOM   5852 C CB   . ASN B 1 84  ? -28.82422 9.09107   -54.72316 1.000 35.63977  ? 84  ASN B CB   1 
ATOM   5853 C CG   . ASN B 1 84  ? -27.78521 9.44958   -55.77293 1.000 37.38176  ? 84  ASN B CG   1 
ATOM   5854 O OD1  . ASN B 1 84  ? -27.95315 9.15262   -56.95620 1.000 35.30327  ? 84  ASN B OD1  1 
ATOM   5855 N ND2  . ASN B 1 84  ? -26.71095 10.10097  -55.34458 1.000 39.87665  ? 84  ASN B ND2  1 
ATOM   5856 H H    . ASN B 1 84  ? -30.04103 11.55292  -55.88301 1.000 41.65789  ? 84  ASN B H    1 
ATOM   5857 H HA   . ASN B 1 84  ? -30.53422 9.45333   -55.75664 1.000 40.51923  ? 84  ASN B HA   1 
ATOM   5858 H HB2  . ASN B 1 84  ? -28.47020 9.33327   -53.85315 1.000 42.76149  ? 84  ASN B HB2  1 
ATOM   5859 H HB3  . ASN B 1 84  ? -28.97713 8.13409   -54.76441 1.000 42.76149  ? 84  ASN B HB3  1 
ATOM   5860 H HD21 . ASN B 1 84  ? -26.09452 10.32609  -55.90041 1.000 47.84575  ? 84  ASN B HD21 1 
ATOM   5861 H HD22 . ASN B 1 84  ? -26.63134 10.29790  -54.51123 1.000 47.84575  ? 84  ASN B HD22 1 
ATOM   5862 N N    . CYS B 1 85  ? -30.70672 8.89800   -52.74033 1.000 37.12545  ? 85  CYS B N    1 
ATOM   5863 C CA   . CYS B 1 85  ? -31.61793 8.45281   -51.69425 1.000 31.40748  ? 85  CYS B CA   1 
ATOM   5864 C C    . CYS B 1 85  ? -31.56030 9.31279   -50.43392 1.000 37.29704  ? 85  CYS B C    1 
ATOM   5865 O O    . CYS B 1 85  ? -32.07924 8.89695   -49.39257 1.000 37.98954  ? 85  CYS B O    1 
ATOM   5866 C CB   . CYS B 1 85  ? -31.33861 6.98884   -51.34930 1.000 30.73421  ? 85  CYS B CB   1 
ATOM   5867 S SG   . CYS B 1 85  ? -31.83097 5.83890   -52.65377 1.000 38.92077  ? 85  CYS B SG   1 
ATOM   5868 H H    . CYS B 1 85  ? -29.88469 8.68616   -52.60255 1.000 44.54432  ? 85  CYS B H    1 
ATOM   5869 H HA   . CYS B 1 85  ? -32.52204 8.52003   -52.03915 1.000 37.68274  ? 85  CYS B HA   1 
ATOM   5870 H HB2  . CYS B 1 85  ? -30.38675 6.87861   -51.19861 1.000 36.87482  ? 85  CYS B HB2  1 
ATOM   5871 H HB3  . CYS B 1 85  ? -31.83069 6.75683   -50.54623 1.000 36.87482  ? 85  CYS B HB3  1 
ATOM   5872 H HG   . CYS B 1 85  ? -31.30371 6.16472   -53.68130 1.000 46.69869  ? 85  CYS B HG   1 
ATOM   5873 N N    . VAL B 1 86  ? -30.96708 10.50607  -50.50293 1.000 37.33453  ? 86  VAL B N    1 
ATOM   5874 C CA   . VAL B 1 86  ? -30.97460 11.42232  -49.36966 1.000 35.46127  ? 86  VAL B CA   1 
ATOM   5875 C C    . VAL B 1 86  ? -31.60443 12.74263  -49.79012 1.000 35.12723  ? 86  VAL B C    1 
ATOM   5876 O O    . VAL B 1 86  ? -31.52477 13.16152  -50.95044 1.000 38.77633  ? 86  VAL B O    1 
ATOM   5877 C CB   . VAL B 1 86  ? -29.56607 11.66875  -48.77571 1.000 34.15583  ? 86  VAL B CB   1 
ATOM   5878 C CG1  . VAL B 1 86  ? -29.00794 10.38155  -48.18592 1.000 49.34192  ? 86  VAL B CG1  1 
ATOM   5879 C CG2  . VAL B 1 86  ? -28.62301 12.24215  -49.81344 1.000 43.46759  ? 86  VAL B CG2  1 
ATOM   5880 H H    . VAL B 1 86  ? -30.55505 10.80379  -51.19661 1.000 44.79521  ? 86  VAL B H    1 
ATOM   5881 H HA   . VAL B 1 86  ? -31.52419 11.02421  -48.67657 1.000 42.54730  ? 86  VAL B HA   1 
ATOM   5882 H HB   . VAL B 1 86  ? -29.64249 12.32262  -48.06331 1.000 40.98077  ? 86  VAL B HB   1 
ATOM   5883 H HG11 . VAL B 1 86  ? -28.10152 10.54147  -47.87977 1.000 59.20407  ? 86  VAL B HG11 1 
ATOM   5884 H HG12 . VAL B 1 86  ? -29.56534 10.10792  -47.44071 1.000 59.20407  ? 86  VAL B HG12 1 
ATOM   5885 H HG13 . VAL B 1 86  ? -29.00951 9.69398   -48.87013 1.000 59.20407  ? 86  VAL B HG13 1 
ATOM   5886 H HG21 . VAL B 1 86  ? -27.73977 12.33135  -49.42252 1.000 52.15488  ? 86  VAL B HG21 1 
ATOM   5887 H HG22 . VAL B 1 86  ? -28.58869 11.64213  -50.57482 1.000 52.15488  ? 86  VAL B HG22 1 
ATOM   5888 H HG23 . VAL B 1 86  ? -28.95081 13.11156  -50.09196 1.000 52.15488  ? 86  VAL B HG23 1 
ATOM   5889 N N    . LEU B 1 87  ? -32.26295 13.37974  -48.82638 1.000 40.64043  ? 87  LEU B N    1 
ATOM   5890 C CA   . LEU B 1 87  ? -32.71049 14.75717  -48.94852 1.000 46.02785  ? 87  LEU B CA   1 
ATOM   5891 C C    . LEU B 1 87  ? -31.62459 15.68696  -48.42773 1.000 45.67372  ? 87  LEU B C    1 
ATOM   5892 O O    . LEU B 1 87  ? -31.00748 15.41921  -47.39222 1.000 43.48081  ? 87  LEU B O    1 
ATOM   5893 C CB   . LEU B 1 87  ? -33.99140 14.98416  -48.14808 1.000 54.74430  ? 87  LEU B CB   1 
ATOM   5894 C CG   . LEU B 1 87  ? -35.30782 15.26113  -48.86952 1.000 53.53573  ? 87  LEU B CG   1 
ATOM   5895 C CD1  . LEU B 1 87  ? -36.37829 15.53893  -47.82360 1.000 50.36751  ? 87  LEU B CD1  1 
ATOM   5896 C CD2  . LEU B 1 87  ? -35.19552 16.41448  -49.84656 1.000 55.70275  ? 87  LEU B CD2  1 
ATOM   5897 H H    . LEU B 1 87  ? -32.46718 13.02270  -48.07112 1.000 48.76229  ? 87  LEU B H    1 
ATOM   5898 H HA   . LEU B 1 87  ? -32.89252 14.95915  -49.87964 1.000 55.22720  ? 87  LEU B HA   1 
ATOM   5899 H HB2  . LEU B 1 87  ? -34.13963 14.18810  -47.61403 1.000 65.68693  ? 87  LEU B HB2  1 
ATOM   5900 H HB3  . LEU B 1 87  ? -33.83575 15.74730  -47.56991 1.000 65.68693  ? 87  LEU B HB3  1 
ATOM   5901 H HG   . LEU B 1 87  ? -35.55435 14.48681  -49.39919 1.000 64.23665  ? 87  LEU B HG   1 
ATOM   5902 H HD11 . LEU B 1 87  ? -36.52913 14.73354  -47.30447 1.000 60.43478  ? 87  LEU B HD11 1 
ATOM   5903 H HD12 . LEU B 1 87  ? -36.07469 16.25448  -47.24332 1.000 60.43478  ? 87  LEU B HD12 1 
ATOM   5904 H HD13 . LEU B 1 87  ? -37.19731 15.80167  -48.27202 1.000 60.43478  ? 87  LEU B HD13 1 
ATOM   5905 H HD21 . LEU B 1 87  ? -36.08613 16.72854  -50.06811 1.000 66.83708  ? 87  LEU B HD21 1 
ATOM   5906 H HD22 . LEU B 1 87  ? -34.68580 17.12929  -49.43410 1.000 66.83708  ? 87  LEU B HD22 1 
ATOM   5907 H HD23 . LEU B 1 87  ? -34.74445 16.10651  -50.64818 1.000 66.83708  ? 87  LEU B HD23 1 
ATOM   5908 N N    . LYS B 1 88  ? -31.39704 16.78034  -49.14486 1.000 49.66604  ? 88  LYS B N    1 
ATOM   5909 C CA   . LYS B 1 88  ? -30.49375 17.83775  -48.70387 1.000 47.37772  ? 88  LYS B CA   1 
ATOM   5910 C C    . LYS B 1 88  ? -31.33125 19.09013  -48.46528 1.000 46.73406  ? 88  LYS B C    1 
ATOM   5911 O O    . LYS B 1 88  ? -31.90732 19.64596  -49.40530 1.000 52.92025  ? 88  LYS B O    1 
ATOM   5912 C CB   . LYS B 1 88  ? -29.38996 18.08094  -49.73123 1.000 45.37540  ? 88  LYS B CB   1 
ATOM   5913 C CG   . LYS B 1 88  ? -28.59068 16.82562  -50.05110 1.000 53.07002  ? 88  LYS B CG   1 
ATOM   5914 C CD   . LYS B 1 88  ? -27.24770 17.13676  -50.68993 1.000 51.15005  ? 88  LYS B CD   1 
ATOM   5915 C CE   . LYS B 1 88  ? -27.41201 17.75265  -52.06583 1.000 60.12107  ? 88  LYS B CE   1 
ATOM   5916 N NZ   . LYS B 1 88  ? -26.10766 17.86220  -52.77555 1.000 67.79943  ? 88  LYS B NZ   1 
ATOM   5917 H H    . LYS B 1 88  ? -31.76235 16.93629  -49.90764 1.000 59.59302  ? 88  LYS B H    1 
ATOM   5918 H HA   . LYS B 1 88  ? -30.06853 17.58556  -47.86931 1.000 56.84704  ? 88  LYS B HA   1 
ATOM   5919 H HB2  . LYS B 1 88  ? -29.79104 18.39892  -50.55521 1.000 54.44425  ? 88  LYS B HB2  1 
ATOM   5920 H HB3  . LYS B 1 88  ? -28.77621 18.74630  -49.38266 1.000 54.44425  ? 88  LYS B HB3  1 
ATOM   5921 H HG2  . LYS B 1 88  ? -28.42648 16.33620  -49.22988 1.000 63.67780  ? 88  LYS B HG2  1 
ATOM   5922 H HG3  . LYS B 1 88  ? -29.09721 16.27591  -50.66929 1.000 63.67780  ? 88  LYS B HG3  1 
ATOM   5923 H HD2  . LYS B 1 88  ? -26.76458 17.76530  -50.13098 1.000 61.37383  ? 88  LYS B HD2  1 
ATOM   5924 H HD3  . LYS B 1 88  ? -26.73886 16.31617  -50.78273 1.000 61.37383  ? 88  LYS B HD3  1 
ATOM   5925 H HE2  . LYS B 1 88  ? -28.00269 17.19676  -52.59778 1.000 72.13906  ? 88  LYS B HE2  1 
ATOM   5926 H HE3  . LYS B 1 88  ? -27.78596 18.64317  -51.97621 1.000 72.13906  ? 88  LYS B HE3  1 
ATOM   5927 H HZ1  . LYS B 1 88  ? -26.23359 18.18322  -53.59603 1.000 81.35309  ? 88  LYS B HZ1  1 
ATOM   5928 H HZ2  . LYS B 1 88  ? -25.56448 18.40972  -52.33139 1.000 81.35309  ? 88  LYS B HZ2  1 
ATOM   5929 H HZ3  . LYS B 1 88  ? -25.72496 17.06085  -52.83452 1.000 81.35309  ? 88  LYS B HZ3  1 
ATOM   5930 N N    . LEU B 1 89  ? -31.41414 19.51915  -47.20864 1.000 44.18585  ? 89  LEU B N    1 
ATOM   5931 C CA   . LEU B 1 89  ? -32.17260 20.70397  -46.82572 1.000 51.61764  ? 89  LEU B CA   1 
ATOM   5932 C C    . LEU B 1 89  ? -31.19679 21.82551  -46.49705 1.000 47.67707  ? 89  LEU B C    1 
ATOM   5933 O O    . LEU B 1 89  ? -30.39018 21.69774  -45.56874 1.000 41.51796  ? 89  LEU B O    1 
ATOM   5934 C CB   . LEU B 1 89  ? -33.07356 20.42080  -45.62346 1.000 44.89176  ? 89  LEU B CB   1 
ATOM   5935 C CG   . LEU B 1 89  ? -33.90164 19.13699  -45.65970 1.000 45.77640  ? 89  LEU B CG   1 
ATOM   5936 C CD1  . LEU B 1 89  ? -34.54704 18.90053  -44.30312 1.000 47.40232  ? 89  LEU B CD1  1 
ATOM   5937 C CD2  . LEU B 1 89  ? -34.95145 19.19652  -46.75071 1.000 48.23836  ? 89  LEU B CD2  1 
ATOM   5938 H H    . LEU B 1 89  ? -31.02958 19.12989  -46.54517 1.000 53.01679  ? 89  LEU B H    1 
ATOM   5939 H HA   . LEU B 1 89  ? -32.73029 20.97968  -47.56995 1.000 61.93494  ? 89  LEU B HA   1 
ATOM   5940 H HB2  . LEU B 1 89  ? -32.51107 20.37166  -44.83474 1.000 53.86388  ? 89  LEU B HB2  1 
ATOM   5941 H HB3  . LEU B 1 89  ? -33.69879 21.15766  -45.53967 1.000 53.86388  ? 89  LEU B HB3  1 
ATOM   5942 H HG   . LEU B 1 89  ? -33.31890 18.38789  -45.86010 1.000 54.92545  ? 89  LEU B HG   1 
ATOM   5943 H HD11 . LEU B 1 89  ? -33.85319 18.85599  -43.62675 1.000 56.87656  ? 89  LEU B HD11 1 
ATOM   5944 H HD12 . LEU B 1 89  ? -35.15168 19.63375  -44.10895 1.000 56.87656  ? 89  LEU B HD12 1 
ATOM   5945 H HD13 . LEU B 1 89  ? -35.03834 18.06454  -44.32855 1.000 56.87656  ? 89  LEU B HD13 1 
ATOM   5946 H HD21 . LEU B 1 89  ? -34.51451 19.36233  -47.60071 1.000 57.87980  ? 89  LEU B HD21 1 
ATOM   5947 H HD22 . LEU B 1 89  ? -35.42365 18.34976  -46.78115 1.000 57.87980  ? 89  LEU B HD22 1 
ATOM   5948 H HD23 . LEU B 1 89  ? -35.57260 19.91469  -46.55244 1.000 57.87980  ? 89  LEU B HD23 1 
ATOM   5949 N N    . LYS B 1 90  ? -31.26681 22.91513  -47.25673 1.000 50.70084  ? 90  LYS B N    1 
ATOM   5950 C CA   . LYS B 1 90  ? -30.48514 24.10204  -46.94242 1.000 48.42074  ? 90  LYS B CA   1 
ATOM   5951 C C    . LYS B 1 90  ? -31.15019 24.85039  -45.79345 1.000 49.92589  ? 90  LYS B C    1 
ATOM   5952 O O    . LYS B 1 90  ? -32.37224 25.03025  -45.78251 1.000 45.33971  ? 90  LYS B O    1 
ATOM   5953 C CB   . LYS B 1 90  ? -30.35327 25.00230  -48.16960 1.000 50.10518  ? 90  LYS B CB   1 
ATOM   5954 C CG   . LYS B 1 90  ? -29.49290 26.23907  -47.93440 1.000 54.56814  ? 90  LYS B CG   1 
ATOM   5955 C CD   . LYS B 1 90  ? -28.54743 26.51292  -49.09915 1.000 65.90213  ? 90  LYS B CD   1 
ATOM   5956 C CE   . LYS B 1 90  ? -27.36036 25.55732  -49.09667 1.000 72.29549  ? 90  LYS B CE   1 
ATOM   5957 N NZ   . LYS B 1 90  ? -26.32956 25.93262  -50.10796 1.000 69.98112  ? 90  LYS B NZ   1 
ATOM   5958 H H    . LYS B 1 90  ? -31.75912 22.99024  -47.95786 1.000 60.83478  ? 90  LYS B H    1 
ATOM   5959 H HA   . LYS B 1 90  ? -29.58947 23.84616  -46.67187 1.000 58.09866  ? 90  LYS B HA   1 
ATOM   5960 H HB2  . LYS B 1 90  ? -29.94840 24.49220  -48.88847 1.000 60.11999  ? 90  LYS B HB2  1 
ATOM   5961 H HB3  . LYS B 1 90  ? -31.23741 25.30225  -48.43273 1.000 60.11999  ? 90  LYS B HB3  1 
ATOM   5962 H HG2  . LYS B 1 90  ? -30.06887 27.01184  -47.82494 1.000 65.47554  ? 90  LYS B HG2  1 
ATOM   5963 H HG3  . LYS B 1 90  ? -28.95814 26.10809  -47.13580 1.000 65.47554  ? 90  LYS B HG3  1 
ATOM   5964 H HD2  . LYS B 1 90  ? -29.02693 26.40017  -49.93477 1.000 79.07633  ? 90  LYS B HD2  1 
ATOM   5965 H HD3  . LYS B 1 90  ? -28.20849 27.41920  -49.03081 1.000 79.07633  ? 90  LYS B HD3  1 
ATOM   5966 H HE2  . LYS B 1 90  ? -26.94299 25.57079  -48.22116 1.000 86.74836  ? 90  LYS B HE2  1 
ATOM   5967 H HE3  . LYS B 1 90  ? -27.67228 24.66204  -49.30177 1.000 86.74836  ? 90  LYS B HE3  1 
ATOM   5968 H HZ1  . LYS B 1 90  ? -26.70794 26.02600  -50.90808 1.000 83.97111  ? 90  LYS B HZ1  1 
ATOM   5969 H HZ2  . LYS B 1 90  ? -25.94440 26.70162  -49.87908 1.000 83.97111  ? 90  LYS B HZ2  1 
ATOM   5970 H HZ3  . LYS B 1 90  ? -25.70543 25.29994  -50.15567 1.000 83.97111  ? 90  LYS B HZ3  1 
ATOM   5971 N N    . VAL B 1 91  ? -30.34796 25.26827  -44.81672 1.000 49.04846  ? 91  VAL B N    1 
ATOM   5972 C CA   . VAL B 1 91  ? -30.84943 25.98144  -43.65139 1.000 50.54693  ? 91  VAL B CA   1 
ATOM   5973 C C    . VAL B 1 91  ? -30.16328 27.33873  -43.57447 1.000 45.27001  ? 91  VAL B C    1 
ATOM   5974 O O    . VAL B 1 91  ? -29.13735 27.58478  -44.21336 1.000 52.82087  ? 91  VAL B O    1 
ATOM   5975 C CB   . VAL B 1 91  ? -30.64302 25.18571  -42.34466 1.000 55.82877  ? 91  VAL B CB   1 
ATOM   5976 C CG1  . VAL B 1 91  ? -31.71825 24.12579  -42.20566 1.000 49.49787  ? 91  VAL B CG1  1 
ATOM   5977 C CG2  . VAL B 1 91  ? -29.25465 24.55203  -42.30625 1.000 44.43752  ? 91  VAL B CG2  1 
ATOM   5978 H H    . VAL B 1 91  ? -29.49655 25.14726  -44.80897 1.000 58.85192  ? 91  VAL B H    1 
ATOM   5979 H HA   . VAL B 1 91  ? -31.80116 26.13414  -43.75991 1.000 60.65009  ? 91  VAL B HA   1 
ATOM   5980 H HB   . VAL B 1 91  ? -30.71018 25.79450  -41.59248 1.000 66.98829  ? 91  VAL B HB   1 
ATOM   5981 H HG11 . VAL B 1 91  ? -32.21142 24.06509  -43.03873 1.000 59.39122  ? 91  VAL B HG11 1 
ATOM   5982 H HG12 . VAL B 1 91  ? -31.29843 23.27421  -42.00699 1.000 59.39122  ? 91  VAL B HG12 1 
ATOM   5983 H HG13 . VAL B 1 91  ? -32.31676 24.37577  -41.48442 1.000 59.39122  ? 91  VAL B HG13 1 
ATOM   5984 H HG21 . VAL B 1 91  ? -29.08594 24.21504  -41.41245 1.000 53.31879  ? 91  VAL B HG21 1 
ATOM   5985 H HG22 . VAL B 1 91  ? -29.22217 23.82363  -42.94599 1.000 53.31879  ? 91  VAL B HG22 1 
ATOM   5986 H HG23 . VAL B 1 91  ? -28.59426 25.22417  -42.53647 1.000 53.31879  ? 91  VAL B HG23 1 
ATOM   5987 N N    . ASP B 1 92  ? -30.75236 28.23151  -42.77935 1.000 48.41455  ? 92  ASP B N    1 
ATOM   5988 C CA   . ASP B 1 92  ? -30.27263 29.60108  -42.66525 1.000 68.86353  ? 92  ASP B CA   1 
ATOM   5989 C C    . ASP B 1 92  ? -29.18502 29.76064  -41.60759 1.000 64.79203  ? 92  ASP B C    1 
ATOM   5990 O O    . ASP B 1 92  ? -28.89914 30.88972  -41.19291 1.000 61.55324  ? 92  ASP B O    1 
ATOM   5991 C CB   . ASP B 1 92  ? -31.43718 30.54400  -42.35342 1.000 60.85595  ? 92  ASP B CB   1 
ATOM   5992 C CG   . ASP B 1 92  ? -31.99237 30.34393  -40.95534 1.000 75.55884  ? 92  ASP B CG   1 
ATOM   5993 O OD1  . ASP B 1 92  ? -31.58655 29.37335  -40.28030 1.000 74.54517  ? 92  ASP B OD1  1 
ATOM   5994 O OD2  . ASP B 1 92  ? -32.83756 31.16063  -40.53053 1.000 78.06079  ? 92  ASP B OD2  1 
ATOM   5995 H H    . ASP B 1 92  ? -31.43994 28.06198  -42.29140 1.000 58.09123  ? 92  ASP B H    1 
ATOM   5996 H HA   . ASP B 1 92  ? -29.89549 29.85824  -43.52114 1.000 82.63001  ? 92  ASP B HA   1 
ATOM   5997 H HB2  . ASP B 1 92  ? -31.13011 31.46122  -42.42634 1.000 73.02092  ? 92  ASP B HB2  1 
ATOM   5998 H HB3  . ASP B 1 92  ? -32.15360 30.38262  -42.98713 1.000 73.02092  ? 92  ASP B HB3  1 
ATOM   5999 N N    . THR B 1 93  ? -28.58046 28.66247  -41.16025 1.000 62.32584  ? 93  THR B N    1 
ATOM   6000 C CA   . THR B 1 93  ? -27.55891 28.71701  -40.12061 1.000 59.45774  ? 93  THR B CA   1 
ATOM   6001 C C    . THR B 1 93  ? -26.53578 27.62805  -40.39677 1.000 57.37670  ? 93  THR B C    1 
ATOM   6002 O O    . THR B 1 93  ? -26.87105 26.44054  -40.35075 1.000 54.51568  ? 93  THR B O    1 
ATOM   6003 C CB   . THR B 1 93  ? -28.17085 28.52731  -38.72733 1.000 59.90625  ? 93  THR B CB   1 
ATOM   6004 O OG1  . THR B 1 93  ? -29.23537 29.46598  -38.53001 1.000 68.01633  ? 93  THR B OG1  1 
ATOM   6005 C CG2  . THR B 1 93  ? -27.11863 28.72152  -37.64062 1.000 50.77399  ? 93  THR B CG2  1 
ATOM   6006 H H    . THR B 1 93  ? -28.74627 27.86834  -41.44566 1.000 74.78478  ? 93  THR B H    1 
ATOM   6007 H HA   . THR B 1 93  ? -27.11813 29.58058  -40.14963 1.000 71.34307  ? 93  THR B HA   1 
ATOM   6008 H HB   . THR B 1 93  ? -28.51973 27.62510  -38.65515 1.000 71.88128  ? 93  THR B HB   1 
ATOM   6009 H HG1  . THR B 1 93  ? -29.65782 29.27804  -37.82872 1.000 81.61336  ? 93  THR B HG1  1 
ATOM   6010 H HG21 . THR B 1 93  ? -26.69288 29.58718  -37.74199 1.000 60.92256  ? 93  THR B HG21 1 
ATOM   6011 H HG22 . THR B 1 93  ? -27.53353 28.67537  -36.76505 1.000 60.92256  ? 93  THR B HG22 1 
ATOM   6012 H HG23 . THR B 1 93  ? -26.44279 28.02877  -37.70562 1.000 60.92256  ? 93  THR B HG23 1 
ATOM   6013 N N    . ALA B 1 94  ? -25.30097 28.02546  -40.69127 1.000 53.01248  ? 94  ALA B N    1 
ATOM   6014 C CA   . ALA B 1 94  ? -24.21099 27.06151  -40.71006 1.000 50.22115  ? 94  ALA B CA   1 
ATOM   6015 C C    . ALA B 1 94  ? -24.00125 26.51280  -39.30433 1.000 54.32284  ? 94  ALA B C    1 
ATOM   6016 O O    . ALA B 1 94  ? -24.08582 27.24630  -38.31518 1.000 49.25477  ? 94  ALA B O    1 
ATOM   6017 C CB   . ALA B 1 94  ? -22.92693 27.70695  -41.22580 1.000 48.03882  ? 94  ALA B CB   1 
ATOM   6018 H H    . ALA B 1 94  ? -25.07364 28.83307  -40.88020 1.000 63.60875  ? 94  ALA B H    1 
ATOM   6019 H HA   . ALA B 1 94  ? -24.42654 26.33008  -41.30960 1.000 60.25915  ? 94  ALA B HA   1 
ATOM   6020 H HB1  . ALA B 1 94  ? -22.21415 27.04925  -41.20922 1.000 57.64036  ? 94  ALA B HB1  1 
ATOM   6021 H HB2  . ALA B 1 94  ? -23.07128 28.01546  -42.13403 1.000 57.64036  ? 94  ALA B HB2  1 
ATOM   6022 H HB3  . ALA B 1 94  ? -22.69864 28.45661  -40.65415 1.000 57.64036  ? 94  ALA B HB3  1 
ATOM   6023 N N    . ASN B 1 95  ? -23.74592 25.21733  -39.21583 1.000 54.40320  ? 95  ASN B N    1 
ATOM   6024 C CA   . ASN B 1 95  ? -23.56194 24.58143  -37.91752 1.000 50.13956  ? 95  ASN B CA   1 
ATOM   6025 C C    . ASN B 1 95  ? -22.24493 25.04861  -37.31482 1.000 42.40676  ? 95  ASN B C    1 
ATOM   6026 O O    . ASN B 1 95  ? -21.18276 24.68668  -37.83587 1.000 41.98255  ? 95  ASN B O    1 
ATOM   6027 C CB   . ASN B 1 95  ? -23.57950 23.05819  -38.05946 1.000 48.75142  ? 95  ASN B CB   1 
ATOM   6028 C CG   . ASN B 1 95  ? -23.53159 22.34406  -36.71692 1.000 45.51713  ? 95  ASN B CG   1 
ATOM   6029 O OD1  . ASN B 1 95  ? -23.46822 22.97871  -35.66232 1.000 45.67509  ? 95  ASN B OD1  1 
ATOM   6030 N ND2  . ASN B 1 95  ? -23.57399 21.01631  -36.75173 1.000 37.99089  ? 95  ASN B ND2  1 
ATOM   6031 H H    . ASN B 1 95  ? -23.67422 24.68557  -39.88791 1.000 65.27761  ? 95  ASN B H    1 
ATOM   6032 H HA   . ASN B 1 95  ? -24.28883 24.82811  -37.32449 1.000 60.16124  ? 95  ASN B HA   1 
ATOM   6033 H HB2  . ASN B 1 95  ? -24.39486 22.79190  -38.51243 1.000 58.49548  ? 95  ASN B HB2  1 
ATOM   6034 H HB3  . ASN B 1 95  ? -22.80702 22.77949  -38.57569 1.000 58.49548  ? 95  ASN B HB3  1 
ATOM   6035 H HD21 . ASN B 1 95  ? -23.54972 20.56597  -36.01947 1.000 45.58284  ? 95  ASN B HD21 1 
ATOM   6036 H HD22 . ASN B 1 95  ? -23.62570 20.60738  -37.50652 1.000 45.58284  ? 95  ASN B HD22 1 
ATOM   6037 N N    . PRO B 1 96  ? -22.25041 25.84011  -36.23648 1.000 50.06037  ? 96  PRO B N    1 
ATOM   6038 C CA   . PRO B 1 96  ? -20.97200 26.31162  -35.67945 1.000 51.47345  ? 96  PRO B CA   1 
ATOM   6039 C C    . PRO B 1 96  ? -20.11440 25.19133  -35.12155 1.000 41.08668  ? 96  PRO B C    1 
ATOM   6040 O O    . PRO B 1 96  ? -18.90907 25.39204  -34.92948 1.000 39.14026  ? 96  PRO B O    1 
ATOM   6041 C CB   . PRO B 1 96  ? -21.40415 27.29401  -34.58164 1.000 44.60064  ? 96  PRO B CB   1 
ATOM   6042 C CG   . PRO B 1 96  ? -22.76751 26.83965  -34.18275 1.000 47.22739  ? 96  PRO B CG   1 
ATOM   6043 C CD   . PRO B 1 96  ? -23.40327 26.25819  -35.41635 1.000 42.75248  ? 96  PRO B CD   1 
ATOM   6044 H HA   . PRO B 1 96  ? -20.46814 26.79639  -36.35176 1.000 61.76191  ? 96  PRO B HA   1 
ATOM   6045 H HB2  . PRO B 1 96  ? -20.78853 27.24669  -33.83352 1.000 53.51454  ? 96  PRO B HB2  1 
ATOM   6046 H HB3  . PRO B 1 96  ? -21.42759 28.19690  -34.93539 1.000 53.51454  ? 96  PRO B HB3  1 
ATOM   6047 H HG2  . PRO B 1 96  ? -22.69479 26.16729  -33.48737 1.000 56.66664  ? 96  PRO B HG2  1 
ATOM   6048 H HG3  . PRO B 1 96  ? -23.28018 27.59704  -33.85959 1.000 56.66664  ? 96  PRO B HG3  1 
ATOM   6049 H HD2  . PRO B 1 96  ? -23.95916 25.49609  -35.19033 1.000 51.29674  ? 96  PRO B HD2  1 
ATOM   6050 H HD3  . PRO B 1 96  ? -23.93053 26.92759  -35.87982 1.000 51.29674  ? 96  PRO B HD3  1 
ATOM   6051 N N    . LYS B 1 97  ? -20.69414 24.02441  -34.85522 1.000 47.67851  ? 97  LYS B N    1 
ATOM   6052 C CA   . LYS B 1 97  ? -19.95046 22.86160  -34.39882 1.000 44.90120  ? 97  LYS B CA   1 
ATOM   6053 C C    . LYS B 1 97  ? -19.48583 21.97317  -35.54352 1.000 41.74543  ? 97  LYS B C    1 
ATOM   6054 O O    . LYS B 1 97  ? -19.03526 20.85040  -35.29243 1.000 43.33191  ? 97  LYS B O    1 
ATOM   6055 C CB   . LYS B 1 97  ? -20.80494 22.03807  -33.43651 1.000 38.17229  ? 97  LYS B CB   1 
ATOM   6056 C CG   . LYS B 1 97  ? -21.02689 22.68592  -32.08796 1.000 36.46576  ? 97  LYS B CG   1 
ATOM   6057 C CD   . LYS B 1 97  ? -22.13899 21.97897  -31.33824 1.000 41.26723  ? 97  LYS B CD   1 
ATOM   6058 C CE   . LYS B 1 97  ? -22.36111 22.57560  -29.96461 1.000 53.00758  ? 97  LYS B CE   1 
ATOM   6059 N NZ   . LYS B 1 97  ? -23.64898 22.11331  -29.37877 1.000 59.38826  ? 97  LYS B NZ   1 
ATOM   6060 H H    . LYS B 1 97  ? -21.53840 23.88091  -34.93420 1.000 57.20798  ? 97  LYS B H    1 
ATOM   6061 H HA   . LYS B 1 97  ? -19.16556 23.17153  -33.92052 1.000 53.87522  ? 97  LYS B HA   1 
ATOM   6062 H HB2  . LYS B 1 97  ? -21.67526 21.89529  -33.84031 1.000 45.80052  ? 97  LYS B HB2  1 
ATOM   6063 H HB3  . LYS B 1 97  ? -20.36607 21.18652  -33.28435 1.000 45.80052  ? 97  LYS B HB3  1 
ATOM   6064 H HG2  . LYS B 1 97  ? -20.21402 22.62880  -31.56176 1.000 43.75268  ? 97  LYS B HG2  1 
ATOM   6065 H HG3  . LYS B 1 97  ? -21.27816 23.61475  -32.21055 1.000 43.75268  ? 97  LYS B HG3  1 
ATOM   6066 H HD2  . LYS B 1 97  ? -22.96477 22.05900  -31.84081 1.000 49.51444  ? 97  LYS B HD2  1 
ATOM   6067 H HD3  . LYS B 1 97  ? -21.90663 21.04361  -31.22867 1.000 49.51444  ? 97  LYS B HD3  1 
ATOM   6068 H HE2  . LYS B 1 97  ? -21.64095 22.30319  -29.37465 1.000 63.60287  ? 97  LYS B HE2  1 
ATOM   6069 H HE3  . LYS B 1 97  ? -22.38565 23.54284  -30.03351 1.000 63.60287  ? 97  LYS B HE3  1 
ATOM   6070 H HZ1  . LYS B 1 97  ? -24.33161 22.47769  -29.81847 1.000 71.25968  ? 97  LYS B HZ1  1 
ATOM   6071 H HZ2  . LYS B 1 97  ? -23.70866 21.22715  -29.43584 1.000 71.25968  ? 97  LYS B HZ2  1 
ATOM   6072 H HZ3  . LYS B 1 97  ? -23.69679 22.35147  -28.52256 1.000 71.25968  ? 97  LYS B HZ3  1 
ATOM   6073 N N    . THR B 1 98  ? -19.58906 22.43870  -36.78258 1.000 37.27572  ? 98  THR B N    1 
ATOM   6074 C CA   . THR B 1 98  ? -19.17150 21.63002  -37.91719 1.000 34.89917  ? 98  THR B CA   1 
ATOM   6075 C C    . THR B 1 98  ? -17.70434 21.25432  -37.74814 1.000 44.09619  ? 98  THR B C    1 
ATOM   6076 O O    . THR B 1 98  ? -16.85902 22.15001  -37.58921 1.000 39.30693  ? 98  THR B O    1 
ATOM   6077 C CB   . THR B 1 98  ? -19.36971 22.37487  -39.23619 1.000 40.80593  ? 98  THR B CB   1 
ATOM   6078 O OG1  . THR B 1 98  ? -20.75284 22.70060  -39.39943 1.000 41.58816  ? 98  THR B OG1  1 
ATOM   6079 C CG2  . THR B 1 98  ? -18.92376 21.51787  -40.42633 1.000 30.12587  ? 98  THR B CG2  1 
ATOM   6080 H H    . THR B 1 98  ? -19.89582 23.21479  -36.99038 1.000 44.72463  ? 98  THR B H    1 
ATOM   6081 H HA   . THR B 1 98  ? -19.71552 20.82777  -37.95352 1.000 41.87277  ? 98  THR B HA   1 
ATOM   6082 H HB   . THR B 1 98  ? -18.83538 23.18433  -39.22307 1.000 48.96089  ? 98  THR B HB   1 
ATOM   6083 H HG1  . THR B 1 98  ? -21.20270 21.99910  -39.50491 1.000 49.89957  ? 98  THR B HG1  1 
ATOM   6084 H HG21 . THR B 1 98  ? -17.98406 21.29338  -40.33987 1.000 36.14482  ? 98  THR B HG21 1 
ATOM   6085 H HG22 . THR B 1 98  ? -19.44163 20.69827  -40.45751 1.000 36.14482  ? 98  THR B HG22 1 
ATOM   6086 H HG23 . THR B 1 98  ? -19.05603 22.00551  -41.25434 1.000 36.14482  ? 98  THR B HG23 1 
ATOM   6087 N N    . PRO B 1 99  ? -17.36017 19.97168  -37.75249 1.000 44.27779  ? 99  PRO B N    1 
ATOM   6088 C CA   . PRO B 1 99  ? -15.95247 19.57432  -37.73113 1.000 29.74629  ? 99  PRO B CA   1 
ATOM   6089 C C    . PRO B 1 99  ? -15.37573 19.54434  -39.14198 1.000 35.36984  ? 99  PRO B C    1 
ATOM   6090 O O    . PRO B 1 99  ? -16.09680 19.60166  -40.13879 1.000 40.70886  ? 99  PRO B O    1 
ATOM   6091 C CB   . PRO B 1 99  ? -16.00441 18.16449  -37.12852 1.000 42.05524  ? 99  PRO B CB   1 
ATOM   6092 C CG   . PRO B 1 99  ? -17.32623 17.62333  -37.58926 1.000 41.69375  ? 99  PRO B CG   1 
ATOM   6093 C CD   . PRO B 1 99  ? -18.26350 18.80509  -37.67472 1.000 43.47308  ? 99  PRO B CD   1 
ATOM   6094 H HA   . PRO B 1 99  ? -15.42117 20.15497  -37.16416 1.000 35.68932  ? 99  PRO B HA   1 
ATOM   6095 H HB2  . PRO B 1 99  ? -15.26913 17.62924  -37.46583 1.000 50.46006  ? 99  PRO B HB2  1 
ATOM   6096 H HB3  . PRO B 1 99  ? -15.96295 18.21269  -36.16061 1.000 50.46006  ? 99  PRO B HB3  1 
ATOM   6097 H HG2  . PRO B 1 99  ? -17.22158 17.20667  -38.45894 1.000 50.02627  ? 99  PRO B HG2  1 
ATOM   6098 H HG3  . PRO B 1 99  ? -17.65311 16.97373  -36.94734 1.000 50.02627  ? 99  PRO B HG3  1 
ATOM   6099 H HD2  . PRO B 1 99  ? -18.81700 18.74672  -38.46916 1.000 52.16147  ? 99  PRO B HD2  1 
ATOM   6100 H HD3  . PRO B 1 99  ? -18.82272 18.85683  -36.88384 1.000 52.16147  ? 99  PRO B HD3  1 
ATOM   6101 N N    . LYS B 1 100 ? -14.04857 19.47372  -39.20355 1.000 38.33620  ? 100 LYS B N    1 
ATOM   6102 C CA   . LYS B 1 100 ? -13.39832 19.06266  -40.43932 1.000 39.92960  ? 100 LYS B CA   1 
ATOM   6103 C C    . LYS B 1 100 ? -13.93400 17.69186  -40.82541 1.000 35.32174  ? 100 LYS B C    1 
ATOM   6104 O O    . LYS B 1 100 ? -13.95442 16.76960  -40.00385 1.000 37.13200  ? 100 LYS B O    1 
ATOM   6105 C CB   . LYS B 1 100 ? -11.88085 19.01075  -40.26973 1.000 42.65017  ? 100 LYS B CB   1 
ATOM   6106 C CG   . LYS B 1 100 ? -11.25073 20.32145  -39.83470 1.000 52.49374  ? 100 LYS B CG   1 
ATOM   6107 C CD   . LYS B 1 100 ? -9.73733  20.29758  -40.01408 1.000 51.93825  ? 100 LYS B CD   1 
ATOM   6108 C CE   . LYS B 1 100 ? -9.06168  21.32389  -39.11789 1.000 63.58650  ? 100 LYS B CE   1 
ATOM   6109 N NZ   . LYS B 1 100 ? -7.91817  22.00648  -39.78640 1.000 71.37355  ? 100 LYS B NZ   1 
ATOM   6110 H H    . LYS B 1 100 ? -13.51348 19.65543  -38.55529 1.000 45.99721  ? 100 LYS B H    1 
ATOM   6111 H HA   . LYS B 1 100 ? -13.58124 19.70402  -41.14367 1.000 47.90930  ? 100 LYS B HA   1 
ATOM   6112 H HB2  . LYS B 1 100 ? -11.66785 18.34565  -39.59655 1.000 51.17398  ? 100 LYS B HB2  1 
ATOM   6113 H HB3  . LYS B 1 100 ? -11.48345 18.76229  -41.11898 1.000 51.17398  ? 100 LYS B HB3  1 
ATOM   6114 H HG2  . LYS B 1 100 ? -11.61036 21.04502  -40.37138 1.000 62.98626  ? 100 LYS B HG2  1 
ATOM   6115 H HG3  . LYS B 1 100 ? -11.44457 20.47593  -38.89691 1.000 62.98626  ? 100 LYS B HG3  1 
ATOM   6116 H HD2  . LYS B 1 100 ? -9.39888  19.41859  -39.78230 1.000 62.31967  ? 100 LYS B HD2  1 
ATOM   6117 H HD3  . LYS B 1 100 ? -9.51850  20.50484  -40.93607 1.000 62.31967  ? 100 LYS B HD3  1 
ATOM   6118 H HE2  . LYS B 1 100 ? -9.70980  22.00053  -38.86690 1.000 76.29757  ? 100 LYS B HE2  1 
ATOM   6119 H HE3  . LYS B 1 100 ? -8.72342  20.87835  -38.32545 1.000 76.29757  ? 100 LYS B HE3  1 
ATOM   6120 H HZ1  . LYS B 1 100 ? -7.40244  22.40230  -39.17858 1.000 85.64203  ? 100 LYS B HZ1  1 
ATOM   6121 H HZ2  . LYS B 1 100 ? -7.43073  21.41340  -40.23669 1.000 85.64203  ? 100 LYS B HZ2  1 
ATOM   6122 H HZ3  . LYS B 1 100 ? -8.22055  22.62204  -40.35362 1.000 85.64203  ? 100 LYS B HZ3  1 
ATOM   6123 N N    . TYR B 1 101 ? -14.38969 17.56096  -42.06712 1.000 37.80239  ? 101 TYR B N    1 
ATOM   6124 C CA   . TYR B 1 101 ? -15.06890 16.34259  -42.46982 1.000 39.90872  ? 101 TYR B CA   1 
ATOM   6125 C C    . TYR B 1 101 ? -14.94636 16.13720  -43.96887 1.000 40.52275  ? 101 TYR B C    1 
ATOM   6126 O O    . TYR B 1 101 ? -14.68430 17.07074  -44.73199 1.000 33.81017  ? 101 TYR B O    1 
ATOM   6127 C CB   . TYR B 1 101 ? -16.55315 16.37324  -42.07924 1.000 43.01855  ? 101 TYR B CB   1 
ATOM   6128 C CG   . TYR B 1 101 ? -17.41128 17.26806  -42.95603 1.000 43.34550  ? 101 TYR B CG   1 
ATOM   6129 C CD1  . TYR B 1 101 ? -17.92230 16.80980  -44.16734 1.000 42.11873  ? 101 TYR B CD1  1 
ATOM   6130 C CD2  . TYR B 1 101 ? -17.72514 18.56312  -42.56487 1.000 36.94808  ? 101 TYR B CD2  1 
ATOM   6131 C CE1  . TYR B 1 101 ? -18.70642 17.62092  -44.96926 1.000 28.63568  ? 101 TYR B CE1  1 
ATOM   6132 C CE2  . TYR B 1 101 ? -18.51398 19.38055  -43.35925 1.000 42.36351  ? 101 TYR B CE2  1 
ATOM   6133 C CZ   . TYR B 1 101 ? -19.00168 18.90320  -44.55875 1.000 40.96151  ? 101 TYR B CZ   1 
ATOM   6134 O OH   . TYR B 1 101 ? -19.78432 19.71433  -45.34883 1.000 42.44692  ? 101 TYR B OH   1 
ATOM   6135 H H    . TYR B 1 101 ? -14.31734 18.15649  -42.68332 1.000 45.35664  ? 101 TYR B H    1 
ATOM   6136 H HA   . TYR B 1 101 ? -14.63237 15.59621  -42.03019 1.000 47.88423  ? 101 TYR B HA   1 
ATOM   6137 H HB2  . TYR B 1 101 ? -16.90853 15.47284  -42.14145 1.000 51.61603  ? 101 TYR B HB2  1 
ATOM   6138 H HB3  . TYR B 1 101 ? -16.62703 16.69684  -41.16779 1.000 51.61603  ? 101 TYR B HB3  1 
ATOM   6139 H HD1  . TYR B 1 101 ? -17.73314 15.94196  -44.44297 1.000 50.53624  ? 101 TYR B HD1  1 
ATOM   6140 H HD2  . TYR B 1 101 ? -17.40048 18.88754  -41.75602 1.000 44.33147  ? 101 TYR B HD2  1 
ATOM   6141 H HE1  . TYR B 1 101 ? -19.03210 17.30267  -45.78016 1.000 34.35659  ? 101 TYR B HE1  1 
ATOM   6142 H HE2  . TYR B 1 101 ? -18.71360 20.24653  -43.08518 1.000 50.82998  ? 101 TYR B HE2  1 
ATOM   6143 H HH   . TYR B 1 101 ? -19.99001 19.31308  -46.05755 1.000 50.93008  ? 101 TYR B HH   1 
ATOM   6144 N N    . LYS B 1 102 ? -15.16066 14.88825  -44.37356 1.000 38.91449  ? 102 LYS B N    1 
ATOM   6145 C CA   . LYS B 1 102 ? -15.30563 14.52563  -45.77312 1.000 42.64932  ? 102 LYS B CA   1 
ATOM   6146 C C    . LYS B 1 102 ? -16.31678 13.39210  -45.85857 1.000 33.21000  ? 102 LYS B C    1 
ATOM   6147 O O    . LYS B 1 102 ? -16.65126 12.75549  -44.85605 1.000 36.90524  ? 102 LYS B O    1 
ATOM   6148 C CB   . LYS B 1 102 ? -13.96381 14.12071  -46.39862 1.000 41.81003  ? 102 LYS B CB   1 
ATOM   6149 C CG   . LYS B 1 102 ? -13.32216 12.88404  -45.79141 1.000 46.00392  ? 102 LYS B CG   1 
ATOM   6150 C CD   . LYS B 1 102 ? -11.80200 12.86751  -45.99555 1.000 54.83358  ? 102 LYS B CD   1 
ATOM   6151 C CE   . LYS B 1 102 ? -11.40613 13.02538  -47.46111 1.000 75.24490  ? 102 LYS B CE   1 
ATOM   6152 N NZ   . LYS B 1 102 ? -9.92029  13.06482  -47.64559 1.000 83.05913  ? 102 LYS B NZ   1 
ATOM   6153 H H    . LYS B 1 102 ? -15.22735 14.21705  -43.84005 1.000 46.69116  ? 102 LYS B H    1 
ATOM   6154 H HA   . LYS B 1 102 ? -15.64294 15.28012  -46.28093 1.000 51.17295  ? 102 LYS B HA   1 
ATOM   6155 H HB2  . LYS B 1 102 ? -14.10561 13.94217  -47.34144 1.000 50.16581  ? 102 LYS B HB2  1 
ATOM   6156 H HB3  . LYS B 1 102 ? -13.33997 14.85555  -46.29027 1.000 50.16581  ? 102 LYS B HB3  1 
ATOM   6157 H HG2  . LYS B 1 102 ? -13.49994 12.86724  -44.83799 1.000 55.19848  ? 102 LYS B HG2  1 
ATOM   6158 H HG3  . LYS B 1 102 ? -13.69288 12.09249  -46.21202 1.000 55.19848  ? 102 LYS B HG3  1 
ATOM   6159 H HD2  . LYS B 1 102 ? -11.40701 13.59996  -45.49717 1.000 65.79407  ? 102 LYS B HD2  1 
ATOM   6160 H HD3  . LYS B 1 102 ? -11.44851 12.02172  -45.67839 1.000 65.79407  ? 102 LYS B HD3  1 
ATOM   6161 H HE2  . LYS B 1 102 ? -11.75343 12.27438  -47.96734 1.000 90.28765  ? 102 LYS B HE2  1 
ATOM   6162 H HE3  . LYS B 1 102 ? -11.77496 13.85485  -47.80291 1.000 90.28765  ? 102 LYS B HE3  1 
ATOM   6163 H HZ1  . LYS B 1 102 ? -9.55959  12.29717  -47.37595 1.000 99.66473  ? 102 LYS B HZ1  1 
ATOM   6164 H HZ2  . LYS B 1 102 ? -9.72341  13.19055  -48.50438 1.000 99.66473  ? 102 LYS B HZ2  1 
ATOM   6165 H HZ3  . LYS B 1 102 ? -9.57194  13.73080  -47.16890 1.000 99.66473  ? 102 LYS B HZ3  1 
ATOM   6166 N N    . PHE B 1 103 ? -16.82413 13.16998  -47.06599 1.000 36.86499  ? 103 PHE B N    1 
ATOM   6167 C CA   . PHE B 1 103 ? -17.69095 12.03958  -47.36364 1.000 33.36043  ? 103 PHE B CA   1 
ATOM   6168 C C    . PHE B 1 103 ? -16.87770 10.98630  -48.10429 1.000 38.21662  ? 103 PHE B C    1 
ATOM   6169 O O    . PHE B 1 103 ? -16.18215 11.30585  -49.07434 1.000 43.09560  ? 103 PHE B O    1 
ATOM   6170 C CB   . PHE B 1 103 ? -18.88581 12.45916  -48.22063 1.000 36.07663  ? 103 PHE B CB   1 
ATOM   6171 C CG   . PHE B 1 103 ? -19.87936 13.34567  -47.51724 1.000 35.35547  ? 103 PHE B CG   1 
ATOM   6172 C CD1  . PHE B 1 103 ? -19.88865 13.46769  -46.13691 1.000 35.23254  ? 103 PHE B CD1  1 
ATOM   6173 C CD2  . PHE B 1 103 ? -20.82335 14.04941  -48.25429 1.000 40.14641  ? 103 PHE B CD2  1 
ATOM   6174 C CE1  . PHE B 1 103 ? -20.81242 14.28147  -45.50474 1.000 33.05556  ? 103 PHE B CE1  1 
ATOM   6175 C CE2  . PHE B 1 103 ? -21.74960 14.86335  -47.63127 1.000 31.43056  ? 103 PHE B CE2  1 
ATOM   6176 C CZ   . PHE B 1 103 ? -21.74618 14.97895  -46.25172 1.000 39.37582  ? 103 PHE B CZ   1 
ATOM   6177 H H    . PHE B 1 103 ? -16.67573 13.67461  -47.74638 1.000 44.23176  ? 103 PHE B H    1 
ATOM   6178 H HA   . PHE B 1 103 ? -18.03243 11.66794  -46.53528 1.000 40.02629  ? 103 PHE B HA   1 
ATOM   6179 H HB2  . PHE B 1 103 ? -18.55648 12.94418  -48.99341 1.000 43.28573  ? 103 PHE B HB2  1 
ATOM   6180 H HB3  . PHE B 1 103 ? -19.35674 11.66063  -48.50608 1.000 43.28573  ? 103 PHE B HB3  1 
ATOM   6181 H HD1  . PHE B 1 103 ? -19.26705 12.99740  -45.62962 1.000 42.27281  ? 103 PHE B HD1  1 
ATOM   6182 H HD2  . PHE B 1 103 ? -20.83195 13.97148  -49.18098 1.000 48.16946  ? 103 PHE B HD2  1 
ATOM   6183 H HE1  . PHE B 1 103 ? -20.80590 14.35975  -44.57806 1.000 39.66045  ? 103 PHE B HE1  1 
ATOM   6184 H HE2  . PHE B 1 103 ? -22.37351 15.33217  -48.13707 1.000 37.71044  ? 103 PHE B HE2  1 
ATOM   6185 H HZ   . PHE B 1 103 ? -22.36951 15.52372  -45.82794 1.000 47.24476  ? 103 PHE B HZ   1 
ATOM   6186 N N    . VAL B 1 104 ? -16.97154 9.73830   -47.65475 1.000 36.93559  ? 104 VAL B N    1 
ATOM   6187 C CA   . VAL B 1 104 ? -16.24493 8.63594   -48.26734 1.000 36.40832  ? 104 VAL B CA   1 
ATOM   6188 C C    . VAL B 1 104 ? -17.20798 7.48244   -48.49206 1.000 32.54269  ? 104 VAL B C    1 
ATOM   6189 O O    . VAL B 1 104 ? -18.20154 7.32899   -47.77529 1.000 40.69866  ? 104 VAL B O    1 
ATOM   6190 C CB   . VAL B 1 104 ? -15.04717 8.17738   -47.40336 1.000 43.21021  ? 104 VAL B CB   1 
ATOM   6191 C CG1  . VAL B 1 104 ? -14.05367 9.31920   -47.22674 1.000 36.27941  ? 104 VAL B CG1  1 
ATOM   6192 C CG2  . VAL B 1 104 ? -15.52736 7.64406   -46.04931 1.000 45.20275  ? 104 VAL B CG2  1 
ATOM   6193 H H    . VAL B 1 104 ? -17.45800 9.50368   -46.98549 1.000 44.31648  ? 104 VAL B H    1 
ATOM   6194 H HA   . VAL B 1 104 ? -15.90363 8.92378   -49.12848 1.000 43.68376  ? 104 VAL B HA   1 
ATOM   6195 H HB   . VAL B 1 104 ? -14.58977 7.45180   -47.85637 1.000 51.84603  ? 104 VAL B HB   1 
ATOM   6196 H HG11 . VAL B 1 104 ? -13.38562 9.05835   -46.57362 1.000 43.52906  ? 104 VAL B HG11 1 
ATOM   6197 H HG12 . VAL B 1 104 ? -13.62883 9.50285   -48.07920 1.000 43.52906  ? 104 VAL B HG12 1 
ATOM   6198 H HG13 . VAL B 1 104 ? -14.52886 10.10630  -46.91761 1.000 43.52906  ? 104 VAL B HG13 1 
ATOM   6199 H HG21 . VAL B 1 104 ? -14.76712 7.57008   -45.45142 1.000 54.23708  ? 104 VAL B HG21 1 
ATOM   6200 H HG22 . VAL B 1 104 ? -16.17950 8.26017   -45.68049 1.000 54.23708  ? 104 VAL B HG22 1 
ATOM   6201 H HG23 . VAL B 1 104 ? -15.93232 6.77221   -46.17890 1.000 54.23708  ? 104 VAL B HG23 1 
ATOM   6202 N N    . ARG B 1 105 ? -16.91340 6.67538   -49.50593 1.000 33.80593  ? 105 ARG B N    1 
ATOM   6203 C CA   . ARG B 1 105 ? -17.60757 5.41676   -49.74142 1.000 37.16665  ? 105 ARG B CA   1 
ATOM   6204 C C    . ARG B 1 105 ? -16.64408 4.28904   -49.40355 1.000 32.68244  ? 105 ARG B C    1 
ATOM   6205 O O    . ARG B 1 105 ? -15.58948 4.16243   -50.03484 1.000 39.17993  ? 105 ARG B O    1 
ATOM   6206 C CB   . ARG B 1 105 ? -18.09301 5.30357   -51.18485 1.000 35.80624  ? 105 ARG B CB   1 
ATOM   6207 C CG   . ARG B 1 105 ? -19.02797 4.12949   -51.40767 1.000 36.54429  ? 105 ARG B CG   1 
ATOM   6208 C CD   . ARG B 1 105 ? -19.62433 4.12569   -52.80150 1.000 42.31295  ? 105 ARG B CD   1 
ATOM   6209 N NE   . ARG B 1 105 ? -20.40129 2.91428   -53.03694 1.000 43.53323  ? 105 ARG B NE   1 
ATOM   6210 C CZ   . ARG B 1 105 ? -21.66055 2.73795   -52.65747 1.000 34.15461  ? 105 ARG B CZ   1 
ATOM   6211 N NH1  . ARG B 1 105 ? -22.33489 3.68712   -52.02850 1.000 38.66051  ? 105 ARG B NH1  1 
ATOM   6212 N NH2  . ARG B 1 105 ? -22.25778 1.57820   -52.91468 1.000 41.94553  ? 105 ARG B NH2  1 
ATOM   6213 H H    . ARG B 1 105 ? -16.29930 6.84095   -50.08478 1.000 40.56088  ? 105 ARG B H    1 
ATOM   6214 H HA   . ARG B 1 105 ? -18.38747 5.35621   -49.16785 1.000 44.59375  ? 105 ARG B HA   1 
ATOM   6215 H HB2  . ARG B 1 105 ? -18.57000 6.11461   -51.42065 1.000 42.96126  ? 105 ARG B HB2  1 
ATOM   6216 H HB3  . ARG B 1 105 ? -17.32536 5.18911   -51.76667 1.000 42.96126  ? 105 ARG B HB3  1 
ATOM   6217 H HG2  . ARG B 1 105 ? -18.53476 3.30279   -51.28851 1.000 43.84691  ? 105 ARG B HG2  1 
ATOM   6218 H HG3  . ARG B 1 105 ? -19.75597 4.17658   -50.76838 1.000 43.84691  ? 105 ARG B HG3  1 
ATOM   6219 H HD2  . ARG B 1 105 ? -20.21132 4.89119   -52.90332 1.000 50.76931  ? 105 ARG B HD2  1 
ATOM   6220 H HD3  . ARG B 1 105 ? -18.91104 4.16498   -53.45768 1.000 50.76931  ? 105 ARG B HD3  1 
ATOM   6221 H HE   . ARG B 1 105 ? -20.01540 2.26728   -53.45177 1.000 52.23365  ? 105 ARG B HE   1 
ATOM   6222 H HH11 . ARG B 1 105 ? -21.95766 4.44055   -51.85633 1.000 46.38639  ? 105 ARG B HH11 1 
ATOM   6223 H HH12 . ARG B 1 105 ? -23.15034 3.55052   -51.79191 1.000 46.38639  ? 105 ARG B HH12 1 
ATOM   6224 H HH21 . ARG B 1 105 ? -21.82824 0.95436   -53.32201 1.000 50.32840  ? 105 ARG B HH21 1 
ATOM   6225 H HH22 . ARG B 1 105 ? -23.07362 1.45191   -52.67373 1.000 50.32840  ? 105 ARG B HH22 1 
ATOM   6226 N N    . ILE B 1 106 ? -16.99971 3.48237   -48.41049 1.000 35.79450  ? 106 ILE B N    1 
ATOM   6227 C CA   . ILE B 1 106 ? -16.08934 2.47301   -47.89654 1.000 34.69909  ? 106 ILE B CA   1 
ATOM   6228 C C    . ILE B 1 106 ? -16.27555 1.17531   -48.66805 1.000 35.16237  ? 106 ILE B C    1 
ATOM   6229 O O    . ILE B 1 106 ? -17.30040 0.93879   -49.31064 1.000 35.21233  ? 106 ILE B O    1 
ATOM   6230 C CB   . ILE B 1 106 ? -16.27948 2.24211   -46.38408 1.000 35.24445  ? 106 ILE B CB   1 
ATOM   6231 C CG1  . ILE B 1 106 ? -17.70745 1.77827   -46.07886 1.000 43.14002  ? 106 ILE B CG1  1 
ATOM   6232 C CG2  . ILE B 1 106 ? -15.93435 3.50530   -45.62594 1.000 38.77286  ? 106 ILE B CG2  1 
ATOM   6233 C CD1  . ILE B 1 106 ? -17.94750 1.47688   -44.60289 1.000 38.68795  ? 106 ILE B CD1  1 
ATOM   6234 H H    . ILE B 1 106 ? -17.76477 3.50147   -48.01817 1.000 42.94717  ? 106 ILE B H    1 
ATOM   6235 H HA   . ILE B 1 106 ? -15.18173 2.78198   -48.04382 1.000 41.63268  ? 106 ILE B HA   1 
ATOM   6236 H HB   . ILE B 1 106 ? -15.67912 1.53643   -46.09689 1.000 42.28711  ? 106 ILE B HB   1 
ATOM   6237 H HG12 . ILE B 1 106 ? -18.32647 2.47645   -46.34394 1.000 51.76180  ? 106 ILE B HG12 1 
ATOM   6238 H HG13 . ILE B 1 106 ? -17.88697 0.96772   -46.58054 1.000 51.76180  ? 106 ILE B HG13 1 
ATOM   6239 H HG21 . ILE B 1 106 ? -16.55664 4.20520   -45.87851 1.000 46.52120  ? 106 ILE B HG21 1 
ATOM   6240 H HG22 . ILE B 1 106 ? -16.00146 3.33067   -44.67415 1.000 46.52120  ? 106 ILE B HG22 1 
ATOM   6241 H HG23 . ILE B 1 106 ? -15.02885 3.77094   -45.85046 1.000 46.52120  ? 106 ILE B HG23 1 
ATOM   6242 H HD11 . ILE B 1 106 ? -18.44077 2.21209   -44.20660 1.000 46.41931  ? 106 ILE B HD11 1 
ATOM   6243 H HD12 . ILE B 1 106 ? -18.45927 0.65635   -44.52729 1.000 46.41931  ? 106 ILE B HD12 1 
ATOM   6244 H HD13 . ILE B 1 106 ? -17.09153 1.37501   -44.15810 1.000 46.41931  ? 106 ILE B HD13 1 
ATOM   6245 N N    . GLN B 1 107 ? -15.26122 0.33363   -48.60295 1.000 44.28047  ? 107 GLN B N    1 
ATOM   6246 C CA   . GLN B 1 107 ? -15.25453 -0.98460  -49.20931 1.000 46.19556  ? 107 GLN B CA   1 
ATOM   6247 C C    . GLN B 1 107 ? -15.76227 -2.01646  -48.21556 1.000 37.43678  ? 107 GLN B C    1 
ATOM   6248 O O    . GLN B 1 107 ? -15.77167 -1.77618  -47.00377 1.000 41.16895  ? 107 GLN B O    1 
ATOM   6249 C CB   . GLN B 1 107 ? -13.83794 -1.34712  -49.65177 1.000 45.45581  ? 107 GLN B CB   1 
ATOM   6250 C CG   . GLN B 1 107 ? -13.24175 -0.41064  -50.68970 1.000 53.60053  ? 107 GLN B CG   1 
ATOM   6251 C CD   . GLN B 1 107 ? -13.80731 -0.64450  -52.08290 1.000 70.98979  ? 107 GLN B CD   1 
ATOM   6252 O OE1  . GLN B 1 107 ? -13.51329 -1.65560  -52.72278 1.000 73.60805  ? 107 GLN B OE1  1 
ATOM   6253 N NE2  . GLN B 1 107 ? -14.62315 0.29126   -52.55799 1.000 67.88162  ? 107 GLN B NE2  1 
ATOM   6254 H H    . GLN B 1 107 ? -14.52666 0.51063   -48.19223 1.000 53.13034  ? 107 GLN B H    1 
ATOM   6255 H HA   . GLN B 1 107 ? -15.82884 -0.99351  -49.99097 1.000 55.42844  ? 107 GLN B HA   1 
ATOM   6256 H HB2  . GLN B 1 107 ? -13.25785 -1.33013  -48.87452 1.000 54.54074  ? 107 GLN B HB2  1 
ATOM   6257 H HB3  . GLN B 1 107 ? -13.85272 -2.23795  -50.03529 1.000 54.54074  ? 107 GLN B HB3  1 
ATOM   6258 H HG2  . GLN B 1 107 ? -13.43452 0.50584   -50.43709 1.000 64.31440  ? 107 GLN B HG2  1 
ATOM   6259 H HG3  . GLN B 1 107 ? -12.28249 -0.54955  -50.72760 1.000 64.31440  ? 107 GLN B HG3  1 
ATOM   6260 H HE21 . GLN B 1 107 ? -14.80612 0.98403   -52.08240 1.000 81.45172  ? 107 GLN B HE21 1 
ATOM   6261 H HE22 . GLN B 1 107 ? -14.96802 0.20389   -53.34095 1.000 81.45172  ? 107 GLN B HE22 1 
ATOM   6262 N N    . PRO B 1 108 ? -16.18899 -3.18508  -48.69013 1.000 38.86713  ? 108 PRO B N    1 
ATOM   6263 C CA   . PRO B 1 108 ? -16.52756 -4.26302  -47.75413 1.000 33.64985  ? 108 PRO B CA   1 
ATOM   6264 C C    . PRO B 1 108 ? -15.30488 -4.65439  -46.93863 1.000 34.38573  ? 108 PRO B C    1 
ATOM   6265 O O    . PRO B 1 108 ? -14.17397 -4.62632  -47.42700 1.000 41.86328  ? 108 PRO B O    1 
ATOM   6266 C CB   . PRO B 1 108 ? -16.99515 -5.40495  -48.66545 1.000 40.91167  ? 108 PRO B CB   1 
ATOM   6267 C CG   . PRO B 1 108 ? -17.26194 -4.77047  -50.00754 1.000 42.66389  ? 108 PRO B CG   1 
ATOM   6268 C CD   . PRO B 1 108 ? -16.32584 -3.60580  -50.09575 1.000 41.03304  ? 108 PRO B CD   1 
ATOM   6269 H HA   . PRO B 1 108 ? -17.25689 -4.00704  -47.16808 1.000 40.37359  ? 108 PRO B HA   1 
ATOM   6270 H HB2  . PRO B 1 108 ? -16.29803 -6.07596  -48.73372 1.000 49.08777  ? 108 PRO B HB2  1 
ATOM   6271 H HB3  . PRO B 1 108 ? -17.80346 -5.80180  -48.30484 1.000 49.08777  ? 108 PRO B HB3  1 
ATOM   6272 H HG2  . PRO B 1 108 ? -17.08319 -5.41032  -50.71432 1.000 51.19044  ? 108 PRO B HG2  1 
ATOM   6273 H HG3  . PRO B 1 108 ? -18.18469 -4.47492  -50.05315 1.000 51.19044  ? 108 PRO B HG3  1 
ATOM   6274 H HD2  . PRO B 1 108 ? -15.46919 -3.87662  -50.46141 1.000 49.23342  ? 108 PRO B HD2  1 
ATOM   6275 H HD3  . PRO B 1 108 ? -16.70685 -2.89500  -50.63473 1.000 49.23342  ? 108 PRO B HD3  1 
ATOM   6276 N N    . GLY B 1 109 ? -15.53964 -5.00638  -45.67928 1.000 37.04445  ? 109 GLY B N    1 
ATOM   6277 C CA   . GLY B 1 109 ? -14.47953 -5.35397  -44.76792 1.000 27.29918  ? 109 GLY B CA   1 
ATOM   6278 C C    . GLY B 1 109 ? -13.97325 -4.20778  -43.92467 1.000 27.58195  ? 109 GLY B C    1 
ATOM   6279 O O    . GLY B 1 109 ? -13.35203 -4.44978  -42.88354 1.000 34.51156  ? 109 GLY B O    1 
ATOM   6280 H H    . GLY B 1 109 ? -16.32446 -5.04958  -45.33029 1.000 44.44711  ? 109 GLY B H    1 
ATOM   6281 H HA2  . GLY B 1 109 ? -14.79912 -6.04556  -44.16753 1.000 32.75279  ? 109 GLY B HA2  1 
ATOM   6282 H HA3  . GLY B 1 109 ? -13.73088 -5.70015  -45.27840 1.000 32.75279  ? 109 GLY B HA3  1 
ATOM   6283 N N    . GLN B 1 110 ? -14.21514 -2.97133  -44.34345 1.000 34.68254  ? 110 GLN B N    1 
ATOM   6284 C CA   . GLN B 1 110 ? -13.82083 -1.81808  -43.55318 1.000 34.47521  ? 110 GLN B CA   1 
ATOM   6285 C C    . GLN B 1 110 ? -14.82550 -1.58149  -42.43162 1.000 40.94787  ? 110 GLN B C    1 
ATOM   6286 O O    . GLN B 1 110 ? -16.01416 -1.89870  -42.54747 1.000 33.02860  ? 110 GLN B O    1 
ATOM   6287 C CB   . GLN B 1 110 ? -13.69546 -0.57946  -44.44198 1.000 32.75378  ? 110 GLN B CB   1 
ATOM   6288 C CG   . GLN B 1 110 ? -12.56435 -0.69361  -45.46844 1.000 43.47113  ? 110 GLN B CG   1 
ATOM   6289 C CD   . GLN B 1 110 ? -12.35116 0.56987   -46.28393 1.000 42.81030  ? 110 GLN B CD   1 
ATOM   6290 O OE1  . GLN B 1 110 ? -13.28593 1.11200   -46.87668 1.000 40.79172  ? 110 GLN B OE1  1 
ATOM   6291 N NE2  . GLN B 1 110 ? -11.11015 1.04239   -46.32113 1.000 61.81725  ? 110 GLN B NE2  1 
ATOM   6292 H H    . GLN B 1 110 ? -14.60709 -2.77528  -45.08340 1.000 41.61282  ? 110 GLN B H    1 
ATOM   6293 H HA   . GLN B 1 110 ? -12.95332 -1.97225  -43.14752 1.000 41.36402  ? 110 GLN B HA   1 
ATOM   6294 H HB2  . GLN B 1 110 ? -14.52699 -0.45301  -44.92517 1.000 39.29831  ? 110 GLN B HB2  1 
ATOM   6295 H HB3  . GLN B 1 110 ? -13.51595 0.19259   -43.88286 1.000 39.29831  ? 110 GLN B HB3  1 
ATOM   6296 H HG2  . GLN B 1 110 ? -11.73670 -0.88761  -45.00127 1.000 52.15913  ? 110 GLN B HG2  1 
ATOM   6297 H HG3  . GLN B 1 110 ? -12.77344 -1.41237  -46.08534 1.000 52.15913  ? 110 GLN B HG3  1 
ATOM   6298 H HE21 . GLN B 1 110 ? -10.48211 0.63518   -45.89764 1.000 74.17447  ? 110 GLN B HE21 1 
ATOM   6299 H HE22 . GLN B 1 110 ? -10.93479 1.75550   -46.76871 1.000 74.17447  ? 110 GLN B HE22 1 
ATOM   6300 N N    . THR B 1 111 ? -14.32649 -1.03313  -41.33087 1.000 33.89938  ? 111 THR B N    1 
ATOM   6301 C CA   . THR B 1 111 ? -15.10960 -0.82087  -40.12627 1.000 37.36128  ? 111 THR B CA   1 
ATOM   6302 C C    . THR B 1 111 ? -15.36772 0.66388   -39.92141 1.000 29.65863  ? 111 THR B C    1 
ATOM   6303 O O    . THR B 1 111 ? -14.70540 1.52303   -40.50979 1.000 30.06469  ? 111 THR B O    1 
ATOM   6304 C CB   . THR B 1 111 ? -14.38991 -1.39558  -38.90116 1.000 41.54425  ? 111 THR B CB   1 
ATOM   6305 O OG1  . THR B 1 111 ? -13.06005 -0.86050  -38.83621 1.000 29.52493  ? 111 THR B OG1  1 
ATOM   6306 C CG2  . THR B 1 111 ? -14.34078 -2.92705  -38.97877 1.000 39.03348  ? 111 THR B CG2  1 
ATOM   6307 H H    . THR B 1 111 ? -13.51145 -0.76859  -41.25782 1.000 40.67303  ? 111 THR B H    1 
ATOM   6308 H HA   . THR B 1 111 ? -15.96545 -1.26834  -40.21671 1.000 44.82731  ? 111 THR B HA   1 
ATOM   6309 H HB   . THR B 1 111 ? -14.86779 -1.15431  -38.09226 1.000 49.84687  ? 111 THR B HB   1 
ATOM   6310 H HG1  . THR B 1 111 ? -12.51823 -1.46340  -38.61586 1.000 35.42369  ? 111 THR B HG1  1 
ATOM   6311 H HG21 . THR B 1 111 ? -15.23357 -3.29307  -38.87946 1.000 46.83394  ? 111 THR B HG21 1 
ATOM   6312 H HG22 . THR B 1 111 ? -13.98034 -3.20442  -39.83553 1.000 46.83394  ? 111 THR B HG22 1 
ATOM   6313 H HG23 . THR B 1 111 ? -13.77658 -3.27713  -38.27166 1.000 46.83394  ? 111 THR B HG23 1 
ATOM   6314 N N    . PHE B 1 112 ? -16.34915 0.95279   -39.07175 1.000 33.70485  ? 112 PHE B N    1 
ATOM   6315 C CA   . PHE B 1 112 ? -16.68212 2.32719   -38.73411 1.000 33.63727  ? 112 PHE B CA   1 
ATOM   6316 C C    . PHE B 1 112 ? -17.51396 2.34182   -37.45989 1.000 35.27840  ? 112 PHE B C    1 
ATOM   6317 O O    . PHE B 1 112 ? -18.07516 1.32261   -37.04746 1.000 30.77112  ? 112 PHE B O    1 
ATOM   6318 C CB   . PHE B 1 112 ? -17.42284 3.02013   -39.88619 1.000 33.31294  ? 112 PHE B CB   1 
ATOM   6319 C CG   . PHE B 1 112 ? -18.69616 2.32721   -40.31814 1.000 36.39345  ? 112 PHE B CG   1 
ATOM   6320 C CD1  . PHE B 1 112 ? -19.91068 2.64140   -39.72474 1.000 35.99554  ? 112 PHE B CD1  1 
ATOM   6321 C CD2  . PHE B 1 112 ? -18.68273 1.39117   -41.34292 1.000 38.75682  ? 112 PHE B CD2  1 
ATOM   6322 C CE1  . PHE B 1 112 ? -21.08563 2.02248   -40.13166 1.000 36.51655  ? 112 PHE B CE1  1 
ATOM   6323 C CE2  . PHE B 1 112 ? -19.85476 0.76640   -41.75476 1.000 37.32119  ? 112 PHE B CE2  1 
ATOM   6324 C CZ   . PHE B 1 112 ? -21.05669 1.08457   -41.14891 1.000 37.25611  ? 112 PHE B CZ   1 
ATOM   6325 H H    . PHE B 1 112 ? -16.83804 0.36579   -38.67677 1.000 40.43959  ? 112 PHE B H    1 
ATOM   6326 H HA   . PHE B 1 112 ? -15.86637 2.82101   -38.55639 1.000 40.35850  ? 112 PHE B HA   1 
ATOM   6327 H HB2  . PHE B 1 112 ? -17.65842 3.91852   -39.60638 1.000 39.96929  ? 112 PHE B HB2  1 
ATOM   6328 H HB3  . PHE B 1 112 ? -16.83323 3.05617   -40.65559 1.000 39.96929  ? 112 PHE B HB3  1 
ATOM   6329 H HD1  . PHE B 1 112 ? -19.93826 3.27540   -39.04490 1.000 43.18841  ? 112 PHE B HD1  1 
ATOM   6330 H HD2  . PHE B 1 112 ? -17.87894 1.17895   -41.75978 1.000 46.50196  ? 112 PHE B HD2  1 
ATOM   6331 H HE1  . PHE B 1 112 ? -21.89151 2.23826   -39.72069 1.000 43.81363  ? 112 PHE B HE1  1 
ATOM   6332 H HE2  . PHE B 1 112 ? -19.83045 0.13501   -42.43714 1.000 44.77920  ? 112 PHE B HE2  1 
ATOM   6333 H HZ   . PHE B 1 112 ? -21.84234 0.66988   -41.42403 1.000 44.70111  ? 112 PHE B HZ   1 
ATOM   6334 N N    . SER B 1 113 ? -17.56709 3.51526   -36.83262 1.000 31.82840  ? 113 SER B N    1 
ATOM   6335 C CA   . SER B 1 113 ? -18.39220 3.73253   -35.65305 1.000 32.14069  ? 113 SER B CA   1 
ATOM   6336 C C    . SER B 1 113 ? -19.77093 4.22452   -36.07088 1.000 36.09013  ? 113 SER B C    1 
ATOM   6337 O O    . SER B 1 113 ? -19.90129 4.98536   -37.03225 1.000 32.52571  ? 113 SER B O    1 
ATOM   6338 C CB   . SER B 1 113 ? -17.74128 4.75235   -34.71786 1.000 31.59092  ? 113 SER B CB   1 
ATOM   6339 O OG   . SER B 1 113 ? -16.48351 4.29673   -34.25566 1.000 39.77937  ? 113 SER B OG   1 
ATOM   6340 H H    . SER B 1 113 ? -17.12566 4.21157   -37.07733 1.000 38.18785  ? 113 SER B H    1 
ATOM   6341 H HA   . SER B 1 113 ? -18.49138 2.89805   -35.16859 1.000 38.56260  ? 113 SER B HA   1 
ATOM   6342 H HB2  . SER B 1 113 ? -17.61591 5.58484   -35.19966 1.000 37.90287  ? 113 SER B HB2  1 
ATOM   6343 H HB3  . SER B 1 113 ? -18.32320 4.89492   -33.95501 1.000 37.90287  ? 113 SER B HB3  1 
ATOM   6344 H HG   . SER B 1 113 ? -16.00243 4.07200   -34.90655 1.000 47.72902  ? 113 SER B HG   1 
ATOM   6345 N N    . VAL B 1 114 ? -20.79751 3.77863   -35.34723 1.000 37.09281  ? 114 VAL B N    1 
ATOM   6346 C CA   . VAL B 1 114 ? -22.17036 4.22998   -35.54572 1.000 28.78435  ? 114 VAL B CA   1 
ATOM   6347 C C    . VAL B 1 114 ? -22.62165 4.97715   -34.30002 1.000 35.11699  ? 114 VAL B C    1 
ATOM   6348 O O    . VAL B 1 114 ? -22.49173 4.46652   -33.18058 1.000 25.87956  ? 114 VAL B O    1 
ATOM   6349 C CB   . VAL B 1 114 ? -23.12840 3.06066   -35.83229 1.000 34.19632  ? 114 VAL B CB   1 
ATOM   6350 C CG1  . VAL B 1 114 ? -24.57849 3.54763   -35.76986 1.000 30.35397  ? 114 VAL B CG1  1 
ATOM   6351 C CG2  . VAL B 1 114 ? -22.82984 2.43535   -37.18351 1.000 38.35395  ? 114 VAL B CG2  1 
ATOM   6352 H H    . VAL B 1 114 ? -20.71875 3.19773   -34.71799 1.000 44.50514  ? 114 VAL B H    1 
ATOM   6353 H HA   . VAL B 1 114 ? -22.18482 4.83659   -36.30250 1.000 34.53500  ? 114 VAL B HA   1 
ATOM   6354 H HB   . VAL B 1 114 ? -23.00224 2.37553   -35.15733 1.000 41.02936  ? 114 VAL B HB   1 
ATOM   6355 H HG11 . VAL B 1 114 ? -24.60742 4.48572   -36.01490 1.000 36.41853  ? 114 VAL B HG11 1 
ATOM   6356 H HG12 . VAL B 1 114 ? -25.11334 3.02724   -36.38956 1.000 36.41853  ? 114 VAL B HG12 1 
ATOM   6357 H HG13 . VAL B 1 114 ? -24.91208 3.43129   -34.86649 1.000 36.41853  ? 114 VAL B HG13 1 
ATOM   6358 H HG21 . VAL B 1 114 ? -22.71229 3.14074   -37.83888 1.000 46.01851  ? 114 VAL B HG21 1 
ATOM   6359 H HG22 . VAL B 1 114 ? -22.01818 1.90860   -37.11531 1.000 46.01851  ? 114 VAL B HG22 1 
ATOM   6360 H HG23 . VAL B 1 114 ? -23.57277 1.86658   -37.43937 1.000 46.01851  ? 114 VAL B HG23 1 
ATOM   6361 N N    . LEU B 1 115 ? -23.16610 6.17422   -34.49823 1.000 34.35303  ? 115 LEU B N    1 
ATOM   6362 C CA   . LEU B 1 115 ? -23.83746 6.92862   -33.44349 1.000 32.53793  ? 115 LEU B CA   1 
ATOM   6363 C C    . LEU B 1 115 ? -25.33653 6.74835   -33.66954 1.000 33.30552  ? 115 LEU B C    1 
ATOM   6364 O O    . LEU B 1 115 ? -25.92252 7.37231   -34.55902 1.000 29.61189  ? 115 LEU B O    1 
ATOM   6365 C CB   . LEU B 1 115 ? -23.42548 8.39557   -33.46823 1.000 29.76558  ? 115 LEU B CB   1 
ATOM   6366 C CG   . LEU B 1 115 ? -24.11470 9.27571   -32.42196 1.000 31.55445  ? 115 LEU B CG   1 
ATOM   6367 C CD1  . LEU B 1 115 ? -23.68504 8.88158   -31.01437 1.000 34.74942  ? 115 LEU B CD1  1 
ATOM   6368 C CD2  . LEU B 1 115 ? -23.84324 10.74784  -32.68451 1.000 30.86505  ? 115 LEU B CD2  1 
ATOM   6369 H H    . LEU B 1 115 ? -23.15918 6.58123   -35.25579 1.000 41.21741  ? 115 LEU B H    1 
ATOM   6370 H HA   . LEU B 1 115 ? -23.59883 6.57656   -32.57170 1.000 39.03929  ? 115 LEU B HA   1 
ATOM   6371 H HB2  . LEU B 1 115 ? -22.46983 8.44857   -33.31067 1.000 35.71247  ? 115 LEU B HB2  1 
ATOM   6372 H HB3  . LEU B 1 115 ? -23.63837 8.75935   -34.34186 1.000 35.71247  ? 115 LEU B HB3  1 
ATOM   6373 H HG   . LEU B 1 115 ? -25.07310 9.14037   -32.48565 1.000 37.85911  ? 115 LEU B HG   1 
ATOM   6374 H HD11 . LEU B 1 115 ? -22.75838 8.59564   -31.03546 1.000 41.69307  ? 115 LEU B HD11 1 
ATOM   6375 H HD12 . LEU B 1 115 ? -23.78128 9.64858   -30.42841 1.000 41.69307  ? 115 LEU B HD12 1 
ATOM   6376 H HD13 . LEU B 1 115 ? -24.24828 8.15543   -30.70394 1.000 41.69307  ? 115 LEU B HD13 1 
ATOM   6377 H HD21 . LEU B 1 115 ? -22.88468 10.89631  -32.68899 1.000 37.03183  ? 115 LEU B HD21 1 
ATOM   6378 H HD22 . LEU B 1 115 ? -24.21945 10.98973  -33.54524 1.000 37.03183  ? 115 LEU B HD22 1 
ATOM   6379 H HD23 . LEU B 1 115 ? -24.25636 11.27516  -31.98298 1.000 37.03183  ? 115 LEU B HD23 1 
ATOM   6380 N N    . ALA B 1 116 ? -25.94913 5.86905   -32.88000 1.000 33.62867  ? 116 ALA B N    1 
ATOM   6381 C CA   . ALA B 1 116 ? -27.36469 5.56276   -33.03342 1.000 32.38862  ? 116 ALA B CA   1 
ATOM   6382 C C    . ALA B 1 116 ? -28.19648 6.63733   -32.34786 1.000 36.66721  ? 116 ALA B C    1 
ATOM   6383 O O    . ALA B 1 116 ? -27.98642 6.93581   -31.16771 1.000 36.27587  ? 116 ALA B O    1 
ATOM   6384 C CB   . ALA B 1 116 ? -27.68072 4.18731   -32.44945 1.000 28.84608  ? 116 ALA B CB   1 
ATOM   6385 H H    . ALA B 1 116 ? -25.56348 5.43529   -32.24539 1.000 40.34818  ? 116 ALA B H    1 
ATOM   6386 H HA   . ALA B 1 116 ? -27.59604 5.54630   -33.97528 1.000 38.86012  ? 116 ALA B HA   1 
ATOM   6387 H HB1  . ALA B 1 116 ? -28.59632 3.95391   -32.66875 1.000 34.60906  ? 116 ALA B HB1  1 
ATOM   6388 H HB2  . ALA B 1 116 ? -27.07262 3.53495   -32.83095 1.000 34.60906  ? 116 ALA B HB2  1 
ATOM   6389 H HB3  . ALA B 1 116 ? -27.56924 4.21989   -31.48643 1.000 34.60906  ? 116 ALA B HB3  1 
ATOM   6390 N N    . CYS B 1 117 ? -29.14094 7.21627   -33.08977 1.000 35.18557  ? 117 CYS B N    1 
ATOM   6391 C CA   . CYS B 1 117 ? -29.89511 8.37180   -32.63113 1.000 41.85055  ? 117 CYS B CA   1 
ATOM   6392 C C    . CYS B 1 117 ? -31.39077 8.14935   -32.80355 1.000 40.55791  ? 117 CYS B C    1 
ATOM   6393 O O    . CYS B 1 117 ? -31.83615 7.36642   -33.64688 1.000 41.00526  ? 117 CYS B O    1 
ATOM   6394 C CB   . CYS B 1 117 ? -29.48442 9.64002   -33.39021 1.000 42.81606  ? 117 CYS B CB   1 
ATOM   6395 S SG   . CYS B 1 117 ? -27.77108 10.12420  -33.13805 1.000 43.66456  ? 117 CYS B SG   1 
ATOM   6396 H H    . CYS B 1 117 ? -29.36371 6.94943   -33.87638 1.000 42.21646  ? 117 CYS B H    1 
ATOM   6397 H HA   . CYS B 1 117 ? -29.72305 8.49158   -31.68405 1.000 50.21443  ? 117 CYS B HA   1 
ATOM   6398 H HB2  . CYS B 1 117 ? -29.61111 9.48810   -34.33982 1.000 51.37305  ? 117 CYS B HB2  1 
ATOM   6399 H HB3  . CYS B 1 117 ? -30.04487 10.37423  -33.09402 1.000 51.37305  ? 117 CYS B HB3  1 
ATOM   6400 H HG   . CYS B 1 117 ? -27.05446 9.26012   -33.56210 1.000 52.39124  ? 117 CYS B HG   1 
ATOM   6401 N N    . TYR B 1 118 ? -32.16046 8.86948   -31.98631 1.000 41.69694  ? 118 TYR B N    1 
ATOM   6402 C CA   . TYR B 1 118 ? -33.61652 8.88545   -32.05781 1.000 38.79621  ? 118 TYR B CA   1 
ATOM   6403 C C    . TYR B 1 118 ? -34.09568 10.29651  -31.74865 1.000 47.26619  ? 118 TYR B C    1 
ATOM   6404 O O    . TYR B 1 118 ? -33.72410 10.86784  -30.71924 1.000 47.10647  ? 118 TYR B O    1 
ATOM   6405 C CB   . TYR B 1 118 ? -34.22516 7.86680   -31.08579 1.000 37.22865  ? 118 TYR B CB   1 
ATOM   6406 C CG   . TYR B 1 118 ? -33.80108 6.45158   -31.40053 1.000 44.22252  ? 118 TYR B CG   1 
ATOM   6407 C CD1  . TYR B 1 118 ? -32.66125 5.90069   -30.82525 1.000 41.74093  ? 118 TYR B CD1  1 
ATOM   6408 C CD2  . TYR B 1 118 ? -34.52079 5.67687   -32.30035 1.000 46.62533  ? 118 TYR B CD2  1 
ATOM   6409 C CE1  . TYR B 1 118 ? -32.26022 4.60936   -31.12728 1.000 41.39845  ? 118 TYR B CE1  1 
ATOM   6410 C CE2  . TYR B 1 118 ? -34.13044 4.38905   -32.60610 1.000 47.21456  ? 118 TYR B CE2  1 
ATOM   6411 C CZ   . TYR B 1 118 ? -32.99956 3.85904   -32.01780 1.000 47.89457  ? 118 TYR B CZ   1 
ATOM   6412 O OH   . TYR B 1 118 ? -32.60987 2.57520   -32.32705 1.000 47.51370  ? 118 TYR B OH   1 
ATOM   6413 H H    . TYR B 1 118 ? -31.84966 9.37289   -31.36214 1.000 50.03010  ? 118 TYR B H    1 
ATOM   6414 H HA   . TYR B 1 118 ? -33.91647 8.65430   -32.95084 1.000 46.54922  ? 118 TYR B HA   1 
ATOM   6415 H HB2  . TYR B 1 118 ? -33.93543 8.07588   -30.18400 1.000 44.66816  ? 118 TYR B HB2  1 
ATOM   6416 H HB3  . TYR B 1 118 ? -35.19243 7.91236   -31.14244 1.000 44.66816  ? 118 TYR B HB3  1 
ATOM   6417 H HD1  . TYR B 1 118 ? -32.15987 6.40739   -30.22795 1.000 50.08288  ? 118 TYR B HD1  1 
ATOM   6418 H HD2  . TYR B 1 118 ? -35.27944 6.03219   -32.70420 1.000 55.94417  ? 118 TYR B HD2  1 
ATOM   6419 H HE1  . TYR B 1 118 ? -31.49818 4.25109   -30.73251 1.000 49.67191  ? 118 TYR B HE1  1 
ATOM   6420 H HE2  . TYR B 1 118 ? -34.62700 3.88044   -33.20580 1.000 56.65124  ? 118 TYR B HE2  1 
ATOM   6421 H HH   . TYR B 1 118 ? -31.81950 2.44596   -32.07366 1.000 57.01022  ? 118 TYR B HH   1 
ATOM   6422 N N    . ASN B 1 119 ? -34.90425 10.85925  -32.65138 1.000 50.26203  ? 119 ASN B N    1 
ATOM   6423 C CA   . ASN B 1 119 ? -35.39356 12.23523  -32.53828 1.000 37.50192  ? 119 ASN B CA   1 
ATOM   6424 C C    . ASN B 1 119 ? -34.24826 13.24086  -32.50347 1.000 46.11949  ? 119 ASN B C    1 
ATOM   6425 O O    . ASN B 1 119 ? -34.33187 14.27244  -31.83130 1.000 44.09411  ? 119 ASN B O    1 
ATOM   6426 C CB   . ASN B 1 119 ? -36.28227 12.41529  -31.30520 1.000 41.49561  ? 119 ASN B CB   1 
ATOM   6427 C CG   . ASN B 1 119 ? -37.52908 11.56695  -31.36142 1.000 39.04009  ? 119 ASN B CG   1 
ATOM   6428 O OD1  . ASN B 1 119 ? -37.81488 10.80701  -30.43977 1.000 56.64535  ? 119 ASN B OD1  1 
ATOM   6429 N ND2  . ASN B 1 119 ? -38.27812 11.68553  -32.45088 1.000 48.64954  ? 119 ASN B ND2  1 
ATOM   6430 H H    . ASN B 1 119 ? -35.18959 10.45424  -33.35434 1.000 60.30821  ? 119 ASN B H    1 
ATOM   6431 H HA   . ASN B 1 119 ? -35.92873 12.42322  -33.32514 1.000 44.99608  ? 119 ASN B HA   1 
ATOM   6432 H HB2  . ASN B 1 119 ? -35.78153 12.16200  -30.51399 1.000 49.78850  ? 119 ASN B HB2  1 
ATOM   6433 H HB3  . ASN B 1 119 ? -36.55329 13.34457  -31.24290 1.000 49.78850  ? 119 ASN B HB3  1 
ATOM   6434 H HD21 . ASN B 1 119 ? -38.99873 11.22281  -32.52973 1.000 58.37323  ? 119 ASN B HD21 1 
ATOM   6435 H HD22 . ASN B 1 119 ? -38.04279 12.22508  -33.07787 1.000 58.37323  ? 119 ASN B HD22 1 
ATOM   6436 N N    . GLY B 1 120 ? -33.17218 12.94984  -33.22767 1.000 41.77828  ? 120 GLY B N    1 
ATOM   6437 C CA   . GLY B 1 120 ? -32.02747 13.82986  -33.27304 1.000 42.07214  ? 120 GLY B CA   1 
ATOM   6438 C C    . GLY B 1 120 ? -31.15215 13.81584  -32.03959 1.000 44.17740  ? 120 GLY B C    1 
ATOM   6439 O O    . GLY B 1 120 ? -30.19943 14.60325  -31.97222 1.000 46.03242  ? 120 GLY B O    1 
ATOM   6440 H H    . GLY B 1 120 ? -33.08672 12.23910  -33.70427 1.000 50.12771  ? 120 GLY B H    1 
ATOM   6441 H HA2  . GLY B 1 120 ? -31.47423 13.57814  -34.02899 1.000 50.48034  ? 120 GLY B HA2  1 
ATOM   6442 H HA3  . GLY B 1 120 ? -32.34155 14.73873  -33.40031 1.000 50.48034  ? 120 GLY B HA3  1 
ATOM   6443 N N    . SER B 1 121 ? -31.43240 12.95010  -31.06332 1.000 43.27105  ? 121 SER B N    1 
ATOM   6444 C CA   . SER B 1 121 ? -30.62751 12.87172  -29.85144 1.000 44.89318  ? 121 SER B CA   1 
ATOM   6445 C C    . SER B 1 121 ? -29.83648 11.57102  -29.81161 1.000 45.84600  ? 121 SER B C    1 
ATOM   6446 O O    . SER B 1 121 ? -30.40590 10.49863  -30.05670 1.000 38.16691  ? 121 SER B O    1 
ATOM   6447 C CB   . SER B 1 121 ? -31.52082 12.97593  -28.61057 1.000 40.07401  ? 121 SER B CB   1 
ATOM   6448 O OG   . SER B 1 121 ? -32.03321 14.28554  -28.45756 1.000 57.58129  ? 121 SER B OG   1 
ATOM   6449 H H    . SER B 1 121 ? -32.08917 12.39526  -31.08332 1.000 51.91903  ? 121 SER B H    1 
ATOM   6450 H HA   . SER B 1 121 ? -29.99544 13.60746  -29.84348 1.000 53.86558  ? 121 SER B HA   1 
ATOM   6451 H HB2  . SER B 1 121 ? -32.26209 12.35732  -28.70407 1.000 48.08259  ? 121 SER B HB2  1 
ATOM   6452 H HB3  . SER B 1 121 ? -30.99689 12.74976  -27.82620 1.000 48.08259  ? 121 SER B HB3  1 
ATOM   6453 H HG   . SER B 1 121 ? -31.42954 14.79966  -28.18034 1.000 69.09132  ? 121 SER B HG   1 
ATOM   6454 N N    . PRO B 1 122 ? -28.53583 11.61608  -29.51248 1.000 44.94714  ? 122 PRO B N    1 
ATOM   6455 C CA   . PRO B 1 122 ? -27.74779 10.37617  -29.47315 1.000 40.79486  ? 122 PRO B CA   1 
ATOM   6456 C C    . PRO B 1 122 ? -28.23722 9.40362   -28.41057 1.000 43.28779  ? 122 PRO B C    1 
ATOM   6457 O O    . PRO B 1 122 ? -28.55735 9.78792   -27.28424 1.000 50.19081  ? 122 PRO B O    1 
ATOM   6458 C CB   . PRO B 1 122 ? -26.32915 10.86857  -29.16162 1.000 38.83437  ? 122 PRO B CB   1 
ATOM   6459 C CG   . PRO B 1 122 ? -26.29983 12.27173  -29.66414 1.000 54.18859  ? 122 PRO B CG   1 
ATOM   6460 C CD   . PRO B 1 122 ? -27.67967 12.81482  -29.42792 1.000 40.93140  ? 122 PRO B CD   1 
ATOM   6461 H HA   . PRO B 1 122 ? -27.77584 9.94139   -30.33980 1.000 48.94760  ? 122 PRO B HA   1 
ATOM   6462 H HB2  . PRO B 1 122 ? -26.16963 10.83734  -28.20533 1.000 46.59501  ? 122 PRO B HB2  1 
ATOM   6463 H HB3  . PRO B 1 122 ? -25.67792 10.31873  -29.62473 1.000 46.59501  ? 122 PRO B HB3  1 
ATOM   6464 H HG2  . PRO B 1 122 ? -25.63938 12.78311  -29.17099 1.000 65.02007  ? 122 PRO B HG2  1 
ATOM   6465 H HG3  . PRO B 1 122 ? -26.08491 12.27705  -30.61002 1.000 65.02007  ? 122 PRO B HG3  1 
ATOM   6466 H HD2  . PRO B 1 122 ? -27.74412 13.22380  -28.55072 1.000 49.11145  ? 122 PRO B HD2  1 
ATOM   6467 H HD3  . PRO B 1 122 ? -27.91899 13.45887  -30.11264 1.000 49.11145  ? 122 PRO B HD3  1 
ATOM   6468 N N    . SER B 1 123 ? -28.27205 8.12572   -28.77897 1.000 41.88240  ? 123 SER B N    1 
ATOM   6469 C CA   . SER B 1 123 ? -28.61570 7.04715   -27.86111 1.000 38.84426  ? 123 SER B CA   1 
ATOM   6470 C C    . SER B 1 123 ? -27.41465 6.21666   -27.44233 1.000 37.83854  ? 123 SER B C    1 
ATOM   6471 O O    . SER B 1 123 ? -27.32823 5.81225   -26.28253 1.000 45.95921  ? 123 SER B O    1 
ATOM   6472 C CB   . SER B 1 123 ? -29.66244 6.12442   -28.49685 1.000 44.95537  ? 123 SER B CB   1 
ATOM   6473 O OG   . SER B 1 123 ? -29.98577 5.04502   -27.63542 1.000 53.12009  ? 123 SER B OG   1 
ATOM   6474 H H    . SER B 1 123 ? -28.09586 7.85343   -29.57548 1.000 50.25265  ? 123 SER B H    1 
ATOM   6475 H HA   . SER B 1 123 ? -29.00769 7.43184   -27.06157 1.000 46.60688  ? 123 SER B HA   1 
ATOM   6476 H HB2  . SER B 1 123 ? -30.46676 6.63677   -28.67425 1.000 53.94021  ? 123 SER B HB2  1 
ATOM   6477 H HB3  . SER B 1 123 ? -29.30592 5.76894   -29.32596 1.000 53.94021  ? 123 SER B HB3  1 
ATOM   6478 H HG   . SER B 1 123 ? -30.43094 5.32395   -26.97996 1.000 63.73788  ? 123 SER B HG   1 
ATOM   6479 N N    . GLY B 1 124 ? -26.48584 5.95655   -28.35428 1.000 42.31409  ? 124 GLY B N    1 
ATOM   6480 C CA   . GLY B 1 124 ? -25.34093 5.11767   -28.04607 1.000 34.57329  ? 124 GLY B CA   1 
ATOM   6481 C C    . GLY B 1 124 ? -24.40345 5.05966   -29.23158 1.000 36.15160  ? 124 GLY B C    1 
ATOM   6482 O O    . GLY B 1 124 ? -24.70528 5.55659   -30.32187 1.000 33.82898  ? 124 GLY B O    1 
ATOM   6483 H H    . GLY B 1 124 ? -26.49696 6.25536   -29.16063 1.000 50.77067  ? 124 GLY B H    1 
ATOM   6484 H HA2  . GLY B 1 124 ? -24.86212 5.47916   -27.28386 1.000 41.48172  ? 124 GLY B HA2  1 
ATOM   6485 H HA3  . GLY B 1 124 ? -25.63740 4.21847   -27.83525 1.000 41.48172  ? 124 GLY B HA3  1 
ATOM   6486 N N    . VAL B 1 125 ? -23.25229 4.43573   -29.00280 1.000 31.39413  ? 125 VAL B N    1 
ATOM   6487 C CA   . VAL B 1 125 ? -22.20805 4.33624   -30.01652 1.000 34.19311  ? 125 VAL B CA   1 
ATOM   6488 C C    . VAL B 1 125 ? -21.67838 2.90861   -30.02725 1.000 34.97757  ? 125 VAL B C    1 
ATOM   6489 O O    . VAL B 1 125 ? -21.49978 2.29135   -28.97173 1.000 35.21550  ? 125 VAL B O    1 
ATOM   6490 C CB   . VAL B 1 125 ? -21.08055 5.36387   -29.76188 1.000 37.62362  ? 125 VAL B CB   1 
ATOM   6491 C CG1  . VAL B 1 125 ? -20.36593 5.07737   -28.45369 1.000 42.65222  ? 125 VAL B CG1  1 
ATOM   6492 C CG2  . VAL B 1 125 ? -20.09496 5.39104   -30.91838 1.000 36.55570  ? 125 VAL B CG2  1 
ATOM   6493 H H    . VAL B 1 125 ? -23.05027 4.05692   -28.25762 1.000 37.66673  ? 125 VAL B H    1 
ATOM   6494 H HA   . VAL B 1 125 ? -22.58220 4.51569   -30.89328 1.000 41.02550  ? 125 VAL B HA   1 
ATOM   6495 H HB   . VAL B 1 125 ? -21.48406 6.24333   -29.69389 1.000 45.14212  ? 125 VAL B HB   1 
ATOM   6496 H HG11 . VAL B 1 125 ? -20.89631 4.45303   -27.93427 1.000 51.17643  ? 125 VAL B HG11 1 
ATOM   6497 H HG12 . VAL B 1 125 ? -19.49665 4.69251   -28.64640 1.000 51.17643  ? 125 VAL B HG12 1 
ATOM   6498 H HG13 . VAL B 1 125 ? -20.25882 5.90776   -27.96392 1.000 51.17643  ? 125 VAL B HG13 1 
ATOM   6499 H HG21 . VAL B 1 125 ? -19.32080 5.91589   -30.66128 1.000 43.86061  ? 125 VAL B HG21 1 
ATOM   6500 H HG22 . VAL B 1 125 ? -19.82497 4.48249   -31.12462 1.000 43.86061  ? 125 VAL B HG22 1 
ATOM   6501 H HG23 . VAL B 1 125 ? -20.52472 5.79168   -31.69019 1.000 43.86061  ? 125 VAL B HG23 1 
ATOM   6502 N N    . TYR B 1 126 ? -21.45085 2.37373   -31.22599 1.000 37.33231  ? 126 TYR B N    1 
ATOM   6503 C CA   . TYR B 1 126 ? -20.90265 1.03272   -31.35961 1.000 33.24685  ? 126 TYR B CA   1 
ATOM   6504 C C    . TYR B 1 126 ? -20.14504 0.91792   -32.67468 1.000 29.94809  ? 126 TYR B C    1 
ATOM   6505 O O    . TYR B 1 126 ? -20.26434 1.75940   -33.56951 1.000 27.78068  ? 126 TYR B O    1 
ATOM   6506 C CB   . TYR B 1 126 ? -21.99672 -0.04022  -31.26042 1.000 34.28398  ? 126 TYR B CB   1 
ATOM   6507 C CG   . TYR B 1 126 ? -23.16948 0.13305   -32.20515 1.000 33.50608  ? 126 TYR B CG   1 
ATOM   6508 C CD1  . TYR B 1 126 ? -23.13136 -0.38170  -33.49073 1.000 34.28324  ? 126 TYR B CD1  1 
ATOM   6509 C CD2  . TYR B 1 126 ? -24.32562 0.79076   -31.80080 1.000 44.38225  ? 126 TYR B CD2  1 
ATOM   6510 C CE1  . TYR B 1 126 ? -24.20306 -0.23613  -34.35216 1.000 31.01749  ? 126 TYR B CE1  1 
ATOM   6511 C CE2  . TYR B 1 126 ? -25.40502 0.93849   -32.65860 1.000 32.78820  ? 126 TYR B CE2  1 
ATOM   6512 C CZ   . TYR B 1 126 ? -25.33397 0.42178   -33.93243 1.000 32.09172  ? 126 TYR B CZ   1 
ATOM   6513 O OH   . TYR B 1 126 ? -26.39533 0.55749   -34.79673 1.000 40.48164  ? 126 TYR B OH   1 
ATOM   6514 H H    . TYR B 1 126 ? -21.60650 2.76941   -31.97353 1.000 44.79254  ? 126 TYR B H    1 
ATOM   6515 H HA   . TYR B 1 126 ? -20.26825 0.88830   -30.64017 1.000 39.88999  ? 126 TYR B HA   1 
ATOM   6516 H HB2  . TYR B 1 126 ? -21.59642 -0.90260  -31.45266 1.000 41.13454  ? 126 TYR B HB2  1 
ATOM   6517 H HB3  . TYR B 1 126 ? -22.35034 -0.03255  -30.35721 1.000 41.13454  ? 126 TYR B HB3  1 
ATOM   6518 H HD1  . TYR B 1 126 ? -22.37135 -0.83324  -33.77952 1.000 41.13366  ? 126 TYR B HD1  1 
ATOM   6519 H HD2  . TYR B 1 126 ? -24.37599 1.13790   -30.93949 1.000 53.25247  ? 126 TYR B HD2  1 
ATOM   6520 H HE1  . TYR B 1 126 ? -24.15854 -0.58284  -35.21397 1.000 37.21476  ? 126 TYR B HE1  1 
ATOM   6521 H HE2  . TYR B 1 126 ? -26.17110 1.38328   -32.37544 1.000 39.33961  ? 126 TYR B HE2  1 
ATOM   6522 H HH   . TYR B 1 126 ? -27.05058 0.89748   -34.39591 1.000 48.57174  ? 126 TYR B HH   1 
ATOM   6523 N N    . GLN B 1 127 ? -19.35972 -0.14990  -32.77185 1.000 36.92257  ? 127 GLN B N    1 
ATOM   6524 C CA   . GLN B 1 127 ? -18.47478 -0.41148  -33.89672 1.000 32.79443  ? 127 GLN B CA   1 
ATOM   6525 C C    . GLN B 1 127 ? -19.06646 -1.52140  -34.75555 1.000 36.36058  ? 127 GLN B C    1 
ATOM   6526 O O    . GLN B 1 127 ? -19.62585 -2.48990  -34.23250 1.000 41.94577  ? 127 GLN B O    1 
ATOM   6527 C CB   . GLN B 1 127 ? -17.08393 -0.81045  -33.38669 1.000 38.36741  ? 127 GLN B CB   1 
ATOM   6528 C CG   . GLN B 1 127 ? -15.97874 -0.77559  -34.42265 1.000 41.12003  ? 127 GLN B CG   1 
ATOM   6529 C CD   . GLN B 1 127 ? -15.60487 0.63028   -34.82176 1.000 33.14761  ? 127 GLN B CD   1 
ATOM   6530 O OE1  . GLN B 1 127 ? -16.27488 1.59155   -34.45206 1.000 40.56628  ? 127 GLN B OE1  1 
ATOM   6531 N NE2  . GLN B 1 127 ? -14.52931 0.75966   -35.58342 1.000 39.21936  ? 127 GLN B NE2  1 
ATOM   6532 H H    . GLN B 1 127 ? -19.32190 -0.76346  -32.17043 1.000 44.30086  ? 127 GLN B H    1 
ATOM   6533 H HA   . GLN B 1 127 ? -18.38207 0.37818   -34.45237 1.000 39.34708  ? 127 GLN B HA   1 
ATOM   6534 H HB2  . GLN B 1 127 ? -16.83288 -0.20092  -32.67511 1.000 46.03466  ? 127 GLN B HB2  1 
ATOM   6535 H HB3  . GLN B 1 127 ? -17.13205 -1.71712  -33.04531 1.000 46.03466  ? 127 GLN B HB3  1 
ATOM   6536 H HG2  . GLN B 1 127 ? -15.18900 -1.20502  -34.05823 1.000 49.33781  ? 127 GLN B HG2  1 
ATOM   6537 H HG3  . GLN B 1 127 ? -16.27477 -1.24551  -35.21792 1.000 49.33781  ? 127 GLN B HG3  1 
ATOM   6538 H HE21 . GLN B 1 127 ? -14.08596 0.06289   -35.82332 1.000 47.05700  ? 127 GLN B HE21 1 
ATOM   6539 H HE22 . GLN B 1 127 ? -14.27418 1.54044   -35.83814 1.000 47.05700  ? 127 GLN B HE22 1 
ATOM   6540 N N    A CYS B 1 128 ? -18.92797 -1.39499  -36.07024 0.500 40.24243  ? 128 CYS B N    1 
ATOM   6541 N N    B CYS B 1 128 ? -18.95725 -1.35758  -36.07806 0.500 40.00733  ? 128 CYS B N    1 
ATOM   6542 C CA   A CYS B 1 128 ? -19.40813 -2.43577  -36.96281 0.500 40.16458  ? 128 CYS B CA   1 
ATOM   6543 C CA   B CYS B 1 128 ? -19.49099 -2.30422  -37.04748 0.500 40.18314  ? 128 CYS B CA   1 
ATOM   6544 C C    A CYS B 1 128 ? -18.58231 -2.42996  -38.23882 0.500 41.01225  ? 128 CYS B C    1 
ATOM   6545 C C    B CYS B 1 128 ? -18.49993 -2.47887  -38.19127 0.500 40.52612  ? 128 CYS B C    1 
ATOM   6546 O O    A CYS B 1 128 ? -17.83145 -1.49304  -38.52159 0.500 36.94235  ? 128 CYS B O    1 
ATOM   6547 O O    B CYS B 1 128 ? -17.53598 -1.72157  -38.33170 0.500 37.91492  ? 128 CYS B O    1 
ATOM   6548 C CB   A CYS B 1 128 ? -20.89012 -2.24974  -37.28832 0.500 39.79810  ? 128 CYS B CB   1 
ATOM   6549 C CB   B CYS B 1 128 ? -20.83122 -1.84161  -37.63669 0.500 39.06916  ? 128 CYS B CB   1 
ATOM   6550 S SG   A CYS B 1 128 ? -21.20701 -0.84846  -38.37263 0.500 42.50744  ? 128 CYS B SG   1 
ATOM   6551 S SG   B CYS B 1 128 ? -22.16837 -1.58539  -36.46626 0.500 33.40852  ? 128 CYS B SG   1 
ATOM   6552 H H    A CYS B 1 128 ? -18.56312 -0.72255  -36.46307 0.500 48.28469  ? 128 CYS B H    1 
ATOM   6553 H H    B CYS B 1 128 ? -18.56592 -0.68465  -36.44362 0.500 48.00257  ? 128 CYS B H    1 
ATOM   6554 H HA   A CYS B 1 128 ? -19.28730 -3.29457  -36.52833 0.500 48.19127  ? 128 CYS B HA   1 
ATOM   6555 H HA   B CYS B 1 128 ? -19.61478 -3.15076  -36.59036 0.500 48.21354  ? 128 CYS B HA   1 
ATOM   6556 H HB2  A CYS B 1 128 ? -21.21727 -3.04905  -37.72990 0.500 47.75149  ? 128 CYS B HB2  1 
ATOM   6557 H HB2  B CYS B 1 128 ? -20.68537 -0.99788  -38.09249 0.500 46.87676  ? 128 CYS B HB2  1 
ATOM   6558 H HB3  A CYS B 1 128 ? -21.37713 -2.10422  -36.46216 0.500 47.75149  ? 128 CYS B HB3  1 
ATOM   6559 H HB3  B CYS B 1 128 ? -21.13059 -2.51309  -38.26945 0.500 46.87676  ? 128 CYS B HB3  1 
ATOM   6560 H HG   A CYS B 1 128 ? -20.69781 -1.05671  -39.43910 0.500 51.00270  ? 128 CYS B HG   1 
ATOM   6561 H HG   B CYS B 1 128 ? -22.40851 -2.62339  -35.91409 0.500 40.08399  ? 128 CYS B HG   1 
ATOM   6562 N N    . ALA B 1 129 ? -18.76019 -3.48453  -39.02257 1.000 40.79130  ? 129 ALA B N    1 
ATOM   6563 C CA   . ALA B 1 129 ? -18.05826 -3.66976  -40.28013 1.000 37.55904  ? 129 ALA B CA   1 
ATOM   6564 C C    . ALA B 1 129 ? -19.08090 -3.70585  -41.40770 1.000 35.32493  ? 129 ALA B C    1 
ATOM   6565 O O    . ALA B 1 129 ? -20.19546 -4.21229  -41.23514 1.000 36.69329  ? 129 ALA B O    1 
ATOM   6566 C CB   . ALA B 1 129 ? -17.23089 -4.95556  -40.27308 1.000 37.90821  ? 129 ALA B CB   1 
ATOM   6567 H H    . ALA B 1 129 ? -19.35517 -4.08762  -38.87467 1.000 48.94333  ? 129 ALA B H    1 
ATOM   6568 H HA   . ALA B 1 129 ? -17.44806 -2.93172  -40.43453 1.000 45.06462  ? 129 ALA B HA   1 
ATOM   6569 H HB1  . ALA B 1 129 ? -16.63945 -4.94631  -39.50430 1.000 45.48363  ? 129 ALA B HB1  1 
ATOM   6570 H HB2  . ALA B 1 129 ? -17.83019 -5.71644  -40.22022 1.000 45.48363  ? 129 ALA B HB2  1 
ATOM   6571 H HB3  . ALA B 1 129 ? -16.71036 -5.00063  -41.09035 1.000 45.48363  ? 129 ALA B HB3  1 
ATOM   6572 N N    . MET B 1 130 ? -18.70940 -3.13189  -42.54674 1.000 32.42134  ? 130 MET B N    1 
ATOM   6573 C CA   . MET B 1 130 ? -19.45354 -3.34531  -43.78124 1.000 32.43896  ? 130 MET B CA   1 
ATOM   6574 C C    . MET B 1 130 ? -19.24220 -4.79125  -44.21719 1.000 31.89749  ? 130 MET B C    1 
ATOM   6575 O O    . MET B 1 130 ? -18.12610 -5.18226  -44.57554 1.000 37.89149  ? 130 MET B O    1 
ATOM   6576 C CB   . MET B 1 130 ? -18.98750 -2.36624  -44.85448 1.000 36.13160  ? 130 MET B CB   1 
ATOM   6577 C CG   . MET B 1 130 ? -19.73369 -2.48438  -46.17629 1.000 44.19005  ? 130 MET B CG   1 
ATOM   6578 S SD   . MET B 1 130 ? -21.48711 -2.10026  -46.01438 1.000 46.11030  ? 130 MET B SD   1 
ATOM   6579 C CE   . MET B 1 130 ? -21.41828 -0.32371  -45.79090 1.000 40.73477  ? 130 MET B CE   1 
ATOM   6580 H H    . MET B 1 130 ? -18.02841 -2.61341  -42.63065 1.000 38.89938  ? 130 MET B H    1 
ATOM   6581 H HA   . MET B 1 130 ? -20.39769 -3.17980  -43.63263 1.000 38.92052  ? 130 MET B HA   1 
ATOM   6582 H HB2  . MET B 1 130 ? -19.11395 -1.46259  -44.52535 1.000 43.35169  ? 130 MET B HB2  1 
ATOM   6583 H HB3  . MET B 1 130 ? -18.04744 -2.52603  -45.03237 1.000 43.35169  ? 130 MET B HB3  1 
ATOM   6584 H HG2  . MET B 1 130 ? -19.34741 -1.86493  -46.81501 1.000 53.02183  ? 130 MET B HG2  1 
ATOM   6585 H HG3  . MET B 1 130 ? -19.65365 -3.39328  -46.50553 1.000 53.02183  ? 130 MET B HG3  1 
ATOM   6586 H HE1  . MET B 1 130 ? -21.06939 -0.12992  -44.90681 1.000 48.87549  ? 130 MET B HE1  1 
ATOM   6587 H HE2  . MET B 1 130 ? -20.83636 0.05732   -46.46699 1.000 48.87549  ? 130 MET B HE2  1 
ATOM   6588 H HE3  . MET B 1 130 ? -22.31270 0.04077   -45.88076 1.000 48.87549  ? 130 MET B HE3  1 
ATOM   6589 N N    . ARG B 1 131 ? -20.30249 -5.59417  -44.16674 1.000 33.88709  ? 131 ARG B N    1 
ATOM   6590 C CA   . ARG B 1 131 ? -20.19317 -6.99240  -44.53995 1.000 33.66759  ? 131 ARG B CA   1 
ATOM   6591 C C    . ARG B 1 131 ? -19.93515 -7.11141  -46.04211 1.000 35.17026  ? 131 ARG B C    1 
ATOM   6592 O O    . ARG B 1 131 ? -20.23158 -6.19198  -46.80798 1.000 32.81090  ? 131 ARG B O    1 
ATOM   6593 C CB   . ARG B 1 131 ? -21.46460 -7.75143  -44.16300 1.000 37.22871  ? 131 ARG B CB   1 
ATOM   6594 C CG   . ARG B 1 131 ? -21.92296 -7.59603  -42.70626 1.000 44.52561  ? 131 ARG B CG   1 
ATOM   6595 C CD   . ARG B 1 131 ? -20.91521 -8.13198  -41.69179 1.000 42.56294  ? 131 ARG B CD   1 
ATOM   6596 N NE   . ARG B 1 131 ? -20.29237 -9.38580  -42.10077 1.000 39.69533  ? 131 ARG B NE   1 
ATOM   6597 C CZ   . ARG B 1 131 ? -19.28037 -9.95985  -41.46304 1.000 33.70244  ? 131 ARG B CZ   1 
ATOM   6598 N NH1  . ARG B 1 131 ? -18.77269 -9.43535  -40.35974 1.000 35.06691  ? 131 ARG B NH1  1 
ATOM   6599 N NH2  . ARG B 1 131 ? -18.75877 -11.08308 -41.94919 1.000 34.07597  ? 131 ARG B NH2  1 
ATOM   6600 H H    . ARG B 1 131 ? -21.08995 -5.35125  -43.92075 1.000 40.65828  ? 131 ARG B H    1 
ATOM   6601 H HA   . ARG B 1 131 ? -19.45296 -7.40085  -44.06439 1.000 40.39488  ? 131 ARG B HA   1 
ATOM   6602 H HB2  . ARG B 1 131 ? -22.18698 -7.43497  -44.72773 1.000 44.66822  ? 131 ARG B HB2  1 
ATOM   6603 H HB3  . ARG B 1 131 ? -21.31218 -8.69678  -44.31787 1.000 44.66822  ? 131 ARG B HB3  1 
ATOM   6604 H HG2  . ARG B 1 131 ? -22.05989 -6.65416  -42.51910 1.000 53.42450  ? 131 ARG B HG2  1 
ATOM   6605 H HG3  . ARG B 1 131 ? -22.75331 -8.08253  -42.58490 1.000 53.42450  ? 131 ARG B HG3  1 
ATOM   6606 H HD2  . ARG B 1 131 ? -20.21101 -7.47569  -41.57225 1.000 51.06930  ? 131 ARG B HD2  1 
ATOM   6607 H HD3  . ARG B 1 131 ? -21.37036 -8.28738  -40.84941 1.000 51.06930  ? 131 ARG B HD3  1 
ATOM   6608 H HE   . ARG B 1 131 ? -20.60114 -9.77854  -42.80077 1.000 47.62816  ? 131 ARG B HE   1 
ATOM   6609 H HH11 . ARG B 1 131 ? -19.09878 -8.70634  -40.04066 1.000 42.07407  ? 131 ARG B HH11 1 
ATOM   6610 H HH12 . ARG B 1 131 ? -18.11658 -9.82340  -39.96158 1.000 42.07407  ? 131 ARG B HH12 1 
ATOM   6611 H HH21 . ARG B 1 131 ? -19.07776 -11.42896 -42.66906 1.000 40.88494  ? 131 ARG B HH21 1 
ATOM   6612 H HH22 . ARG B 1 131 ? -18.10262 -11.46326 -41.54357 1.000 40.88494  ? 131 ARG B HH22 1 
ATOM   6613 N N    . PRO B 1 132 ? -19.35821 -8.23366  -46.48358 1.000 37.80617  ? 132 PRO B N    1 
ATOM   6614 C CA   . PRO B 1 132 ? -19.17827 -8.44009  -47.93198 1.000 39.09408  ? 132 PRO B CA   1 
ATOM   6615 C C    . PRO B 1 132 ? -20.46178 -8.33783  -48.73977 1.000 35.32618  ? 132 PRO B C    1 
ATOM   6616 O O    . PRO B 1 132 ? -20.40149 -7.98554  -49.92411 1.000 43.39760  ? 132 PRO B O    1 
ATOM   6617 C CB   . PRO B 1 132 ? -18.57531 -9.84987  -48.00594 1.000 38.47906  ? 132 PRO B CB   1 
ATOM   6618 C CG   . PRO B 1 132 ? -17.83372 -10.00041 -46.71249 1.000 39.04759  ? 132 PRO B CG   1 
ATOM   6619 C CD   . PRO B 1 132 ? -18.62359 -9.23184  -45.68301 1.000 34.27143  ? 132 PRO B CD   1 
ATOM   6620 H HA   . PRO B 1 132 ? -18.54230 -7.79289  -48.27486 1.000 46.90667  ? 132 PRO B HA   1 
ATOM   6621 H HB2  . PRO B 1 132 ? -19.28108 -10.51072 -48.08382 1.000 46.16864  ? 132 PRO B HB2  1 
ATOM   6622 H HB3  . PRO B 1 132 ? -17.97384 -9.91592  -48.76408 1.000 46.16864  ? 132 PRO B HB3  1 
ATOM   6623 H HG2  . PRO B 1 132 ? -17.78241 -10.93917 -46.47372 1.000 46.85088  ? 132 PRO B HG2  1 
ATOM   6624 H HG3  . PRO B 1 132 ? -16.94104 -9.63210  -46.80399 1.000 46.85088  ? 132 PRO B HG3  1 
ATOM   6625 H HD2  . PRO B 1 132 ? -19.23881 -9.81709  -45.21408 1.000 41.11949  ? 132 PRO B HD2  1 
ATOM   6626 H HD3  . PRO B 1 132 ? -18.03164 -8.79675  -45.04962 1.000 41.11949  ? 132 PRO B HD3  1 
ATOM   6627 N N    . ASN B 1 133 ? -21.61915 -8.63544  -48.15238 1.000 36.13174  ? 133 ASN B N    1 
ATOM   6628 C CA   . ASN B 1 133 ? -22.89130 -8.46070  -48.84168 1.000 37.48659  ? 133 ASN B CA   1 
ATOM   6629 C C    . ASN B 1 133 ? -23.46930 -7.05482  -48.67105 1.000 36.21365  ? 133 ASN B C    1 
ATOM   6630 O O    . ASN B 1 133 ? -24.65120 -6.84402  -48.96233 1.000 35.34764  ? 133 ASN B O    1 
ATOM   6631 C CB   . ASN B 1 133 ? -23.90211 -9.50461  -48.35990 1.000 35.42006  ? 133 ASN B CB   1 
ATOM   6632 C CG   . ASN B 1 133 ? -24.26904 -9.33534  -46.90472 1.000 33.54506  ? 133 ASN B CG   1 
ATOM   6633 O OD1  . ASN B 1 133 ? -23.82338 -8.39946  -46.23915 1.000 31.38351  ? 133 ASN B OD1  1 
ATOM   6634 N ND2  . ASN B 1 133 ? -25.09338 -10.24397 -46.40006 1.000 35.21565  ? 133 ASN B ND2  1 
ATOM   6635 H H    . ASN B 1 133 ? -21.69136 -8.94119  -47.35182 1.000 43.35186  ? 133 ASN B H    1 
ATOM   6636 H HA   . ASN B 1 133 ? -22.74785 -8.60608  -49.78994 1.000 44.97768  ? 133 ASN B HA   1 
ATOM   6637 H HB2  . ASN B 1 133 ? -24.71372 -9.42450  -48.88505 1.000 42.49785  ? 133 ASN B HB2  1 
ATOM   6638 H HB3  . ASN B 1 133 ? -23.52044 -10.38930 -48.47193 1.000 42.49785  ? 133 ASN B HB3  1 
ATOM   6639 H HD21 . ASN B 1 133 ? -25.33491 -10.19501 -45.57613 1.000 42.25256  ? 133 ASN B HD21 1 
ATOM   6640 H HD22 . ASN B 1 133 ? -25.38624 -10.88198 -46.89682 1.000 42.25256  ? 133 ASN B HD22 1 
ATOM   6641 N N    . PHE B 1 134 ? -22.66674 -6.09721  -48.20022 1.000 38.12530  ? 134 PHE B N    1 
ATOM   6642 C CA   . PHE B 1 134 ? -23.05008 -4.68647  -48.11808 1.000 42.37557  ? 134 PHE B CA   1 
ATOM   6643 C C    . PHE B 1 134 ? -24.19318 -4.44243  -47.13592 1.000 37.77931  ? 134 PHE B C    1 
ATOM   6644 O O    . PHE B 1 134 ? -24.93946 -3.46783  -47.26706 1.000 35.58619  ? 134 PHE B O    1 
ATOM   6645 C CB   . PHE B 1 134 ? -23.40807 -4.13115  -49.50073 1.000 42.40347  ? 134 PHE B CB   1 
ATOM   6646 C CG   . PHE B 1 134 ? -22.23767 -4.05673  -50.43747 1.000 37.21796  ? 134 PHE B CG   1 
ATOM   6647 C CD1  . PHE B 1 134 ? -21.30539 -3.04132  -50.31660 1.000 38.66626  ? 134 PHE B CD1  1 
ATOM   6648 C CD2  . PHE B 1 134 ? -22.06188 -5.00683  -51.43025 1.000 49.91601  ? 134 PHE B CD2  1 
ATOM   6649 C CE1  . PHE B 1 134 ? -20.21837 -2.97010  -51.17279 1.000 51.70447  ? 134 PHE B CE1  1 
ATOM   6650 C CE2  . PHE B 1 134 ? -20.97826 -4.94030  -52.29043 1.000 45.70166  ? 134 PHE B CE2  1 
ATOM   6651 C CZ   . PHE B 1 134 ? -20.05498 -3.92118  -52.15962 1.000 40.77151  ? 134 PHE B CZ   1 
ATOM   6652 H H    . PHE B 1 134 ? -21.86969 -6.24546  -47.91330 1.000 45.74414  ? 134 PHE B H    1 
ATOM   6653 H HA   . PHE B 1 134 ? -22.28638 -4.19222  -47.78135 1.000 50.84446  ? 134 PHE B HA   1 
ATOM   6654 H HB2  . PHE B 1 134 ? -24.07636 -4.70612  -49.90534 1.000 50.87793  ? 134 PHE B HB2  1 
ATOM   6655 H HB3  . PHE B 1 134 ? -23.76195 -3.23415  -49.39556 1.000 50.87793  ? 134 PHE B HB3  1 
ATOM   6656 H HD1  . PHE B 1 134 ? -21.40974 -2.39873  -49.65246 1.000 46.39328  ? 134 PHE B HD1  1 
ATOM   6657 H HD2  . PHE B 1 134 ? -22.67848 -5.69720  -51.52019 1.000 59.89298  ? 134 PHE B HD2  1 
ATOM   6658 H HE1  . PHE B 1 134 ? -19.59929 -2.28198  -51.08262 1.000 62.03914  ? 134 PHE B HE1  1 
ATOM   6659 H HE2  . PHE B 1 134 ? -20.87235 -5.58145  -52.95572 1.000 54.83577  ? 134 PHE B HE2  1 
ATOM   6660 H HZ   . PHE B 1 134 ? -19.32551 -3.87603  -52.73472 1.000 48.91958  ? 134 PHE B HZ   1 
ATOM   6661 N N    . THR B 1 135 ? -24.33788 -5.31771  -46.15069 1.000 35.83950  ? 135 THR B N    1 
ATOM   6662 C CA   . THR B 1 135 ? -25.15385 -5.06182  -44.97659 1.000 34.65663  ? 135 THR B CA   1 
ATOM   6663 C C    . THR B 1 135 ? -24.24007 -4.77795  -43.79067 1.000 36.49078  ? 135 THR B C    1 
ATOM   6664 O O    . THR B 1 135 ? -23.01927 -4.95155  -43.85946 1.000 35.44271  ? 135 THR B O    1 
ATOM   6665 C CB   . THR B 1 135 ? -26.06244 -6.25585  -44.67129 1.000 41.07088  ? 135 THR B CB   1 
ATOM   6666 O OG1  . THR B 1 135 ? -25.26177 -7.36466  -44.24058 1.000 40.91781  ? 135 THR B OG1  1 
ATOM   6667 C CG2  . THR B 1 135 ? -26.86109 -6.65549  -45.90580 1.000 36.45502  ? 135 THR B CG2  1 
ATOM   6668 H H    . THR B 1 135 ? -23.96065 -6.09050  -46.14113 1.000 43.00117  ? 135 THR B H    1 
ATOM   6669 H HA   . THR B 1 135 ? -25.72136 -4.29094  -45.13341 1.000 41.58173  ? 135 THR B HA   1 
ATOM   6670 H HB   . THR B 1 135 ? -26.68956 -6.01575  -43.97132 1.000 49.27882  ? 135 THR B HB   1 
ATOM   6671 H HG1  . THR B 1 135 ? -25.75280 -8.02448  -44.06995 1.000 49.09514  ? 135 THR B HG1  1 
ATOM   6672 H HG21 . THR B 1 135 ? -26.26644 -7.01007  -46.58519 1.000 43.73979  ? 135 THR B HG21 1 
ATOM   6673 H HG22 . THR B 1 135 ? -27.51373 -7.33438  -45.67327 1.000 43.73979  ? 135 THR B HG22 1 
ATOM   6674 H HG23 . THR B 1 135 ? -27.32479 -5.88308  -46.26533 1.000 43.73979  ? 135 THR B HG23 1 
ATOM   6675 N N    . ILE B 1 136 ? -24.83926 -4.33490  -42.68983 1.000 30.53112  ? 136 ILE B N    1 
ATOM   6676 C CA   . ILE B 1 136 ? -24.12731 -4.22515  -41.42471 1.000 41.39707  ? 136 ILE B CA   1 
ATOM   6677 C C    . ILE B 1 136 ? -24.99054 -4.85915  -40.34546 1.000 34.89941  ? 136 ILE B C    1 
ATOM   6678 O O    . ILE B 1 136 ? -26.22353 -4.86380  -40.43100 1.000 32.65591  ? 136 ILE B O    1 
ATOM   6679 C CB   . ILE B 1 136 ? -23.76058 -2.76547  -41.05836 1.000 41.10515  ? 136 ILE B CB   1 
ATOM   6680 C CG1  . ILE B 1 136 ? -24.99436 -1.95047  -40.67309 1.000 34.78867  ? 136 ILE B CG1  1 
ATOM   6681 C CG2  . ILE B 1 136 ? -23.03712 -2.08622  -42.21643 1.000 38.56096  ? 136 ILE B CG2  1 
ATOM   6682 C CD1  . ILE B 1 136 ? -24.67734 -0.48469  -40.40107 1.000 42.94283  ? 136 ILE B CD1  1 
ATOM   6683 H H    . ILE B 1 136 ? -25.66302 -4.09072  -42.65233 1.000 36.63111  ? 136 ILE B H    1 
ATOM   6684 H HA   . ILE B 1 136 ? -23.29255 -4.71511  -41.48809 1.000 49.67026  ? 136 ILE B HA   1 
ATOM   6685 H HB   . ILE B 1 136 ? -23.17208 -2.80607  -40.28835 1.000 49.31995  ? 136 ILE B HB   1 
ATOM   6686 H HG12 . ILE B 1 136 ? -25.63622 -1.98825  -41.39938 1.000 41.74018  ? 136 ILE B HG12 1 
ATOM   6687 H HG13 . ILE B 1 136 ? -25.38203 -2.32747  -39.86780 1.000 41.74018  ? 136 ILE B HG13 1 
ATOM   6688 H HG21 . ILE B 1 136 ? -23.69449 -1.74384  -42.84216 1.000 46.26692  ? 136 ILE B HG21 1 
ATOM   6689 H HG22 . ILE B 1 136 ? -22.49993 -1.35707  -41.86905 1.000 46.26692  ? 136 ILE B HG22 1 
ATOM   6690 H HG23 . ILE B 1 136 ? -22.46752 -2.73578  -42.65748 1.000 46.26692  ? 136 ILE B HG23 1 
ATOM   6691 H HD11 . ILE B 1 136 ? -23.88695 -0.43114  -39.84132 1.000 51.52517  ? 136 ILE B HD11 1 
ATOM   6692 H HD12 . ILE B 1 136 ? -24.51610 -0.03456  -41.24504 1.000 51.52517  ? 136 ILE B HD12 1 
ATOM   6693 H HD13 . ILE B 1 136 ? -25.43192 -0.07724  -39.94775 1.000 51.52517  ? 136 ILE B HD13 1 
ATOM   6694 N N    . LYS B 1 137 ? -24.33518 -5.42017  -39.33619 1.000 39.69259  ? 137 LYS B N    1 
ATOM   6695 C CA   . LYS B 1 137 ? -25.01774 -6.03626  -38.20121 1.000 42.26241  ? 137 LYS B CA   1 
ATOM   6696 C C    . LYS B 1 137 ? -25.09381 -4.99855  -37.08286 1.000 34.99822  ? 137 LYS B C    1 
ATOM   6697 O O    . LYS B 1 137 ? -24.15579 -4.85062  -36.29657 1.000 37.17421  ? 137 LYS B O    1 
ATOM   6698 C CB   . LYS B 1 137 ? -24.28399 -7.29280  -37.74935 1.000 42.63313  ? 137 LYS B CB   1 
ATOM   6699 C CG   . LYS B 1 137 ? -23.93000 -8.25497  -38.87416 1.000 45.69933  ? 137 LYS B CG   1 
ATOM   6700 C CD   . LYS B 1 137 ? -23.09620 -9.42423  -38.35439 1.000 49.86285  ? 137 LYS B CD   1 
ATOM   6701 C CE   . LYS B 1 137 ? -23.32972 -10.69971 -39.16384 1.000 58.21745  ? 137 LYS B CE   1 
ATOM   6702 N NZ   . LYS B 1 137 ? -24.75053 -11.15803 -39.08171 1.000 68.91940  ? 137 LYS B NZ   1 
ATOM   6703 H H    . LYS B 1 137 ? -23.47759 -5.45780  -39.28396 1.000 47.62488  ? 137 LYS B H    1 
ATOM   6704 H HA   . LYS B 1 137 ? -25.91986 -6.28311  -38.45839 1.000 50.70866  ? 137 LYS B HA   1 
ATOM   6705 H HB2  . LYS B 1 137 ? -23.45624 -7.02901  -37.31791 1.000 51.15353  ? 137 LYS B HB2  1 
ATOM   6706 H HB3  . LYS B 1 137 ? -24.84778 -7.77087  -37.12126 1.000 51.15353  ? 137 LYS B HB3  1 
ATOM   6707 H HG2  . LYS B 1 137 ? -24.74434 -8.60875  -39.26478 1.000 54.83296  ? 137 LYS B HG2  1 
ATOM   6708 H HG3  . LYS B 1 137 ? -23.41435 -7.78682  -39.54931 1.000 54.83296  ? 137 LYS B HG3  1 
ATOM   6709 H HD2  . LYS B 1 137 ? -22.15518 -9.19643  -38.41341 1.000 59.82919  ? 137 LYS B HD2  1 
ATOM   6710 H HD3  . LYS B 1 137 ? -23.33706 -9.60293  -37.43192 1.000 59.82919  ? 137 LYS B HD3  1 
ATOM   6711 H HE2  . LYS B 1 137 ? -23.11860 -10.53054 -40.09535 1.000 69.85471  ? 137 LYS B HE2  1 
ATOM   6712 H HE3  . LYS B 1 137 ? -22.76226 -11.40636 -38.81810 1.000 69.85471  ? 137 LYS B HE3  1 
ATOM   6713 H HZ1  . LYS B 1 137 ? -25.27734 -10.59830 -39.53035 1.000 82.69705  ? 137 LYS B HZ1  1 
ATOM   6714 H HZ2  . LYS B 1 137 ? -24.82855 -11.97212 -39.43280 1.000 82.69705  ? 137 LYS B HZ2  1 
ATOM   6715 H HZ3  . LYS B 1 137 ? -25.01348 -11.18358 -38.23183 1.000 82.69705  ? 137 LYS B HZ3  1 
ATOM   6716 N N    . GLY B 1 138 ? -26.21647 -4.28718  -37.00807 1.000 38.26103  ? 138 GLY B N    1 
ATOM   6717 C CA   . GLY B 1 138 ? -26.34266 -3.17801  -36.08131 1.000 41.21781  ? 138 GLY B CA   1 
ATOM   6718 C C    . GLY B 1 138 ? -27.46331 -3.33592  -35.07664 1.000 35.69680  ? 138 GLY B C    1 
ATOM   6719 O O    . GLY B 1 138 ? -28.05479 -4.41055  -34.95840 1.000 39.56141  ? 138 GLY B O    1 
ATOM   6720 H H    . GLY B 1 138 ? -26.91723 -4.43057  -37.48554 1.000 45.90701  ? 138 GLY B H    1 
ATOM   6721 H HA2  . GLY B 1 138 ? -25.51198 -3.08369  -35.58941 1.000 49.45515  ? 138 GLY B HA2  1 
ATOM   6722 H HA3  . GLY B 1 138 ? -26.50560 -2.36507  -36.58478 1.000 49.45515  ? 138 GLY B HA3  1 
ATOM   6723 N N    . SER B 1 139 ? -27.75597 -2.26538  -34.34171 1.000 35.28686  ? 139 SER B N    1 
ATOM   6724 C CA   . SER B 1 139 ? -28.85951 -2.22149  -33.38250 1.000 36.96216  ? 139 SER B CA   1 
ATOM   6725 C C    . SER B 1 139 ? -29.66132 -0.96331  -33.70920 1.000 38.03157  ? 139 SER B C    1 
ATOM   6726 O O    . SER B 1 139 ? -29.23224 0.15265   -33.39920 1.000 36.93225  ? 139 SER B O    1 
ATOM   6727 C CB   . SER B 1 139 ? -28.34250 -2.21556  -31.94739 1.000 37.80558  ? 139 SER B CB   1 
ATOM   6728 O OG   . SER B 1 139 ? -29.37951 -2.48623  -31.02156 1.000 43.21596  ? 139 SER B OG   1 
ATOM   6729 H H    . SER B 1 139 ? -27.31550 -1.52784  -34.38192 1.000 42.33800  ? 139 SER B H    1 
ATOM   6730 H HA   . SER B 1 139 ? -29.43196 -2.99823  -33.48187 1.000 44.34836  ? 139 SER B HA   1 
ATOM   6731 H HB2  . SER B 1 139 ? -27.65752 -2.89657  -31.85841 1.000 45.36047  ? 139 SER B HB2  1 
ATOM   6732 H HB3  . SER B 1 139 ? -27.96892 -1.34182  -31.75266 1.000 45.36047  ? 139 SER B HB3  1 
ATOM   6733 H HG   . SER B 1 139 ? -29.96446 -1.88469  -31.06140 1.000 51.85292  ? 139 SER B HG   1 
ATOM   6734 N N    . PHE B 1 140 ? -30.81810 -1.14130  -34.34527 1.000 38.51782  ? 140 PHE B N    1 
ATOM   6735 C CA   . PHE B 1 140 ? -31.55812 -0.03174  -34.93682 1.000 40.94310  ? 140 PHE B CA   1 
ATOM   6736 C C    . PHE B 1 140 ? -33.04891 -0.24678  -34.73222 1.000 39.49547  ? 140 PHE B C    1 
ATOM   6737 O O    . PHE B 1 140 ? -33.60326 -1.24189  -35.20703 1.000 44.99695  ? 140 PHE B O    1 
ATOM   6738 C CB   . PHE B 1 140 ? -31.24165 0.09161   -36.43296 1.000 43.14266  ? 140 PHE B CB   1 
ATOM   6739 C CG   . PHE B 1 140 ? -29.91807 0.74797   -36.73294 1.000 40.88156  ? 140 PHE B CG   1 
ATOM   6740 C CD1  . PHE B 1 140 ? -29.58382 1.97022   -36.17017 1.000 38.62484  ? 140 PHE B CD1  1 
ATOM   6741 C CD2  . PHE B 1 140 ? -29.01100 0.14081   -37.58588 1.000 41.48651  ? 140 PHE B CD2  1 
ATOM   6742 C CE1  . PHE B 1 140 ? -28.36845 2.57085   -36.45338 1.000 46.01402  ? 140 PHE B CE1  1 
ATOM   6743 C CE2  . PHE B 1 140 ? -27.79671 0.73739   -37.87411 1.000 39.12425  ? 140 PHE B CE2  1 
ATOM   6744 C CZ   . PHE B 1 140 ? -27.47614 1.95202   -37.31026 1.000 39.13323  ? 140 PHE B CZ   1 
ATOM   6745 H H    . PHE B 1 140 ? -31.19842 -1.90578  -34.44787 1.000 46.21516  ? 140 PHE B H    1 
ATOM   6746 H HA   . PHE B 1 140 ? -31.31137 0.79095   -34.48605 1.000 49.12550  ? 140 PHE B HA   1 
ATOM   6747 H HB2  . PHE B 1 140 ? -31.22355 -0.79746  -36.82042 1.000 51.76496  ? 140 PHE B HB2  1 
ATOM   6748 H HB3  . PHE B 1 140 ? -31.93550 0.62290   -36.85391 1.000 51.76496  ? 140 PHE B HB3  1 
ATOM   6749 H HD1  . PHE B 1 140 ? -30.18228 2.39135   -35.59624 1.000 46.34358  ? 140 PHE B HD1  1 
ATOM   6750 H HD2  . PHE B 1 140 ? -29.22140 -0.67952  -37.97018 1.000 49.77758  ? 140 PHE B HD2  1 
ATOM   6751 H HE1  . PHE B 1 140 ? -28.15251 3.38920   -36.06794 1.000 55.21060  ? 140 PHE B HE1  1 
ATOM   6752 H HE2  . PHE B 1 140 ? -27.19715 0.31834   -38.44841 1.000 46.94287  ? 140 PHE B HE2  1 
ATOM   6753 H HZ   . PHE B 1 140 ? -26.66125 2.35557   -37.50516 1.000 46.95364  ? 140 PHE B HZ   1 
ATOM   6754 N N    . LEU B 1 141 ? -33.69493 0.68494   -34.03380 1.000 44.39001  ? 141 LEU B N    1 
ATOM   6755 C CA   . LEU B 1 141 ? -35.13860 0.68737   -33.87704 1.000 49.40124  ? 141 LEU B CA   1 
ATOM   6756 C C    . LEU B 1 141 ? -35.76354 1.68417   -34.84782 1.000 43.50313  ? 141 LEU B C    1 
ATOM   6757 O O    . LEU B 1 141 ? -35.07221 2.41168   -35.56656 1.000 45.34878  ? 141 LEU B O    1 
ATOM   6758 C CB   . LEU B 1 141 ? -35.53625 1.03837   -32.44190 1.000 44.46569  ? 141 LEU B CB   1 
ATOM   6759 C CG   . LEU B 1 141 ? -35.00036 0.15916   -31.31142 1.000 53.01576  ? 141 LEU B CG   1 
ATOM   6760 C CD1  . LEU B 1 141 ? -35.31690 0.79248   -29.96061 1.000 44.73412  ? 141 LEU B CD1  1 
ATOM   6761 C CD2  . LEU B 1 141 ? -35.56846 -1.24739  -31.38083 1.000 46.84070  ? 141 LEU B CD2  1 
ATOM   6762 H H    . LEU B 1 141 ? -33.30548 1.33919   -33.63395 1.000 53.26178  ? 141 LEU B H    1 
ATOM   6763 H HA   . LEU B 1 141 ? -35.46317 -0.20460  -34.07690 1.000 59.27526  ? 141 LEU B HA   1 
ATOM   6764 H HB2  . LEU B 1 141 ? -35.22733 1.94033   -32.26321 1.000 53.35260  ? 141 LEU B HB2  1 
ATOM   6765 H HB3  . LEU B 1 141 ? -36.50406 1.00228   -32.38754 1.000 53.35260  ? 141 LEU B HB3  1 
ATOM   6766 H HG   . LEU B 1 141 ? -34.03778 0.08731   -31.40727 1.000 63.61268  ? 141 LEU B HG   1 
ATOM   6767 H HD11 . LEU B 1 141 ? -34.78644 0.35659   -29.27540 1.000 53.67471  ? 141 LEU B HD11 1 
ATOM   6768 H HD12 . LEU B 1 141 ? -35.09967 1.73718   -29.99607 1.000 53.67471  ? 141 LEU B HD12 1 
ATOM   6769 H HD13 . LEU B 1 141 ? -36.26121 0.67708   -29.77124 1.000 53.67471  ? 141 LEU B HD13 1 
ATOM   6770 H HD21 . LEU B 1 141 ? -35.57551 -1.53985  -32.30566 1.000 56.20262  ? 141 LEU B HD21 1 
ATOM   6771 H HD22 . LEU B 1 141 ? -35.01185 -1.83929  -30.85097 1.000 56.20262  ? 141 LEU B HD22 1 
ATOM   6772 H HD23 . LEU B 1 141 ? -36.47243 -1.24058  -31.02915 1.000 56.20262  ? 141 LEU B HD23 1 
ATOM   6773 N N    . ASN B 1 142 ? -37.09558 1.71271   -34.86816 1.000 51.62321  ? 142 ASN B N    1 
ATOM   6774 C CA   . ASN B 1 142 ? -37.80268 2.73273   -35.62733 1.000 38.00269  ? 142 ASN B CA   1 
ATOM   6775 C C    . ASN B 1 142 ? -37.41151 4.10410   -35.09458 1.000 44.79559  ? 142 ASN B C    1 
ATOM   6776 O O    . ASN B 1 142 ? -37.26552 4.30094   -33.88472 1.000 50.55121  ? 142 ASN B O    1 
ATOM   6777 C CB   . ASN B 1 142 ? -39.31751 2.53033   -35.53541 1.000 43.95767  ? 142 ASN B CB   1 
ATOM   6778 C CG   . ASN B 1 142 ? -40.07823 3.26780   -36.63742 1.000 55.10183  ? 142 ASN B CG   1 
ATOM   6779 O OD1  . ASN B 1 142 ? -39.55935 3.46950   -37.73589 1.000 59.24153  ? 142 ASN B OD1  1 
ATOM   6780 N ND2  . ASN B 1 142 ? -41.31340 3.67131   -36.34378 1.000 62.54366  ? 142 ASN B ND2  1 
ATOM   6781 H H    . ASN B 1 142 ? -37.60533 1.15737   -34.45421 1.000 61.94162  ? 142 ASN B H    1 
ATOM   6782 H HA   . ASN B 1 142 ? -37.56732 2.67367   -36.56649 1.000 45.59700  ? 142 ASN B HA   1 
ATOM   6783 H HB2  . ASN B 1 142 ? -39.51578 1.58416   -35.61509 1.000 52.74298  ? 142 ASN B HB2  1 
ATOM   6784 H HB3  . ASN B 1 142 ? -39.63002 2.86388   -34.67984 1.000 52.74298  ? 142 ASN B HB3  1 
ATOM   6785 H HD21 . ASN B 1 142 ? -41.78015 4.09033   -36.93213 1.000 75.04616  ? 142 ASN B HD21 1 
ATOM   6786 H HD22 . ASN B 1 142 ? -41.64402 3.51277   -35.56586 1.000 75.04616  ? 142 ASN B HD22 1 
ATOM   6787 N N    . GLY B 1 143 ? -37.22250 5.04978   -36.00925 1.000 41.41022  ? 143 GLY B N    1 
ATOM   6788 C CA   . GLY B 1 143 ? -36.68448 6.34576   -35.67103 1.000 44.59968  ? 143 GLY B CA   1 
ATOM   6789 C C    . GLY B 1 143 ? -35.17914 6.45803   -35.78620 1.000 39.67991  ? 143 GLY B C    1 
ATOM   6790 O O    . GLY B 1 143 ? -34.64972 7.57248   -35.70142 1.000 40.96708  ? 143 GLY B O    1 
ATOM   6791 H H    . GLY B 1 143 ? -37.40365 4.95580   -36.84469 1.000 49.68604  ? 143 GLY B H    1 
ATOM   6792 H HA2  . GLY B 1 143 ? -37.07681 7.00866   -36.26055 1.000 53.51338  ? 143 GLY B HA2  1 
ATOM   6793 H HA3  . GLY B 1 143 ? -36.92774 6.55396   -34.75540 1.000 53.51338  ? 143 GLY B HA3  1 
ATOM   6794 N N    . SER B 1 144 ? -34.47087 5.34556   -35.97778 1.000 40.06505  ? 144 SER B N    1 
ATOM   6795 C CA   . SER B 1 144 ? -33.01928 5.37897   -36.09519 1.000 39.99863  ? 144 SER B CA   1 
ATOM   6796 C C    . SER B 1 144 ? -32.53835 5.86700   -37.45529 1.000 38.91843  ? 144 SER B C    1 
ATOM   6797 O O    . SER B 1 144 ? -31.34681 6.16347   -37.59825 1.000 37.99883  ? 144 SER B O    1 
ATOM   6798 C CB   . SER B 1 144 ? -32.44227 3.98875   -35.83315 1.000 38.72596  ? 144 SER B CB   1 
ATOM   6799 O OG   . SER B 1 144 ? -32.79972 3.09502   -36.87164 1.000 45.65772  ? 144 SER B OG   1 
ATOM   6800 H H    . SER B 1 144 ? -34.81080 4.55829   -36.04302 1.000 48.07183  ? 144 SER B H    1 
ATOM   6801 H HA   . SER B 1 144 ? -32.67418 5.98588   -35.42179 1.000 47.99212  ? 144 SER B HA   1 
ATOM   6802 H HB2  . SER B 1 144 ? -31.47532 4.05086   -35.78803 1.000 46.46492  ? 144 SER B HB2  1 
ATOM   6803 H HB3  . SER B 1 144 ? -32.79277 3.65392   -34.99295 1.000 46.46492  ? 144 SER B HB3  1 
ATOM   6804 H HG   . SER B 1 144 ? -32.86782 2.31466   -36.56835 1.000 54.78303  ? 144 SER B HG   1 
ATOM   6805 N N    . CYS B 1 145 ? -33.42413 5.95411   -38.44739 1.000 44.33795  ? 145 CYS B N    1 
ATOM   6806 C CA   . CYS B 1 145 ? -33.03709 6.44289   -39.76427 1.000 39.88402  ? 145 CYS B CA   1 
ATOM   6807 C C    . CYS B 1 145 ? -32.36641 7.80578   -39.65422 1.000 41.95308  ? 145 CYS B C    1 
ATOM   6808 O O    . CYS B 1 145 ? -32.74417 8.64092   -38.82777 1.000 37.45872  ? 145 CYS B O    1 
ATOM   6809 C CB   . CYS B 1 145 ? -34.26322 6.52566   -40.67376 1.000 44.82695  ? 145 CYS B CB   1 
ATOM   6810 S SG   . CYS B 1 145 ? -35.03179 4.92622   -40.97740 1.000 69.51990  ? 145 CYS B SG   1 
ATOM   6811 H H    . CYS B 1 145 ? -34.25350 5.73631   -38.38174 1.000 53.19931  ? 145 CYS B H    1 
ATOM   6812 H HA   . CYS B 1 145 ? -32.40459 5.82620   -40.16495 1.000 47.85459  ? 145 CYS B HA   1 
ATOM   6813 H HB2  . CYS B 1 145 ? -34.92450 7.10026   -40.25730 1.000 53.78612  ? 145 CYS B HB2  1 
ATOM   6814 H HB3  . CYS B 1 145 ? -33.99465 6.89496   -41.52956 1.000 53.78612  ? 145 CYS B HB3  1 
ATOM   6815 N N    . GLY B 1 146 ? -31.35811 8.02364   -40.49605 1.000 37.50395  ? 146 GLY B N    1 
ATOM   6816 C CA   . GLY B 1 146 ? -30.54743 9.21613   -40.42384 1.000 39.27442  ? 146 GLY B CA   1 
ATOM   6817 C C    . GLY B 1 146 ? -29.37280 9.12297   -39.47571 1.000 38.12827  ? 146 GLY B C    1 
ATOM   6818 O O    . GLY B 1 146 ? -28.51621 10.01785  -39.48864 1.000 36.44727  ? 146 GLY B O    1 
ATOM   6819 H H    . GLY B 1 146 ? -31.12748 7.48269   -41.12358 1.000 44.99851  ? 146 GLY B H    1 
ATOM   6820 H HA2  . GLY B 1 146 ? -30.20023 9.41082   -41.30840 1.000 47.12308  ? 146 GLY B HA2  1 
ATOM   6821 H HA3  . GLY B 1 146 ? -31.10515 9.95488   -40.13385 1.000 47.12308  ? 146 GLY B HA3  1 
ATOM   6822 N N    . SER B 1 147 ? -29.32571 8.09376   -38.62988 1.000 37.05195  ? 147 SER B N    1 
ATOM   6823 C CA   . SER B 1 147 ? -28.10999 7.78070   -37.89223 1.000 29.44546  ? 147 SER B CA   1 
ATOM   6824 C C    . SER B 1 147 ? -26.97200 7.53687   -38.87689 1.000 39.62152  ? 147 SER B C    1 
ATOM   6825 O O    . SER B 1 147 ? -27.18326 7.04291   -39.98802 1.000 34.53239  ? 147 SER B O    1 
ATOM   6826 C CB   . SER B 1 147 ? -28.32529 6.55168   -37.00473 1.000 32.84980  ? 147 SER B CB   1 
ATOM   6827 O OG   . SER B 1 147 ? -29.13175 6.86528   -35.87917 1.000 34.11373  ? 147 SER B OG   1 
ATOM   6828 H H    . SER B 1 147 ? -29.98361 7.56424   -38.46746 1.000 44.45611  ? 147 SER B H    1 
ATOM   6829 H HA   . SER B 1 147 ? -27.86840 8.51867   -37.31091 1.000 35.32832  ? 147 SER B HA   1 
ATOM   6830 H HB2  . SER B 1 147 ? -28.76633 5.86187   -37.52488 1.000 39.41353  ? 147 SER B HB2  1 
ATOM   6831 H HB3  . SER B 1 147 ? -27.46317 6.23313   -36.69461 1.000 39.41353  ? 147 SER B HB3  1 
ATOM   6832 H HG   . SER B 1 147 ? -29.89415 7.11146   -36.13164 1.000 40.93025  ? 147 SER B HG   1 
ATOM   6833 N N    . VAL B 1 148 ? -25.75283 7.89393   -38.47131 1.000 33.69725  ? 148 VAL B N    1 
ATOM   6834 C CA   . VAL B 1 148 ? -24.62169 7.87488   -39.38846 1.000 37.86889  ? 148 VAL B CA   1 
ATOM   6835 C C    . VAL B 1 148 ? -23.48582 7.03230   -38.82914 1.000 31.81205  ? 148 VAL B C    1 
ATOM   6836 O O    . VAL B 1 148 ? -23.32243 6.88261   -37.61407 1.000 29.93514  ? 148 VAL B O    1 
ATOM   6837 C CB   . VAL B 1 148 ? -24.11732 9.30332   -39.70962 1.000 30.53359  ? 148 VAL B CB   1 
ATOM   6838 C CG1  . VAL B 1 148 ? -25.24693 10.14443  -40.28283 1.000 37.51065  ? 148 VAL B CG1  1 
ATOM   6839 C CG2  . VAL B 1 148 ? -23.52428 9.95396   -38.48106 1.000 28.90116  ? 148 VAL B CG2  1 
ATOM   6840 H H    . VAL B 1 148 ? -25.56073 8.14916   -37.67283 1.000 40.43047  ? 148 VAL B H    1 
ATOM   6841 H HA   . VAL B 1 148 ? -24.91599 7.44738   -40.20794 1.000 45.43643  ? 148 VAL B HA   1 
ATOM   6842 H HB   . VAL B 1 148 ? -23.41535 9.24650   -40.37664 1.000 36.63407  ? 148 VAL B HB   1 
ATOM   6843 H HG11 . VAL B 1 148 ? -25.97262 9.55878   -40.54983 1.000 45.00655  ? 148 VAL B HG11 1 
ATOM   6844 H HG12 . VAL B 1 148 ? -25.55510 10.76443  -39.60347 1.000 45.00655  ? 148 VAL B HG12 1 
ATOM   6845 H HG13 . VAL B 1 148 ? -24.91689 10.63416  -41.05234 1.000 45.00655  ? 148 VAL B HG13 1 
ATOM   6846 H HG21 . VAL B 1 148 ? -23.53387 10.91685  -38.59786 1.000 34.67517  ? 148 VAL B HG21 1 
ATOM   6847 H HG22 . VAL B 1 148 ? -24.05500 9.70937   -37.70684 1.000 34.67517  ? 148 VAL B HG22 1 
ATOM   6848 H HG23 . VAL B 1 148 ? -22.61224 9.64349   -38.36837 1.000 34.67517  ? 148 VAL B HG23 1 
ATOM   6849 N N    . GLY B 1 149 ? -22.70240 6.47042   -39.74370 1.000 27.61907  ? 149 GLY B N    1 
ATOM   6850 C CA   . GLY B 1 149 ? -21.46329 5.80804   -39.39861 1.000 32.61089  ? 149 GLY B CA   1 
ATOM   6851 C C    . GLY B 1 149 ? -20.28347 6.65084   -39.83243 1.000 32.06253  ? 149 GLY B C    1 
ATOM   6852 O O    . GLY B 1 149 ? -20.40748 7.45530   -40.76080 1.000 27.88852  ? 149 GLY B O    1 
ATOM   6853 H H    . GLY B 1 149 ? -22.87436 6.46197   -40.58629 1.000 33.13666  ? 149 GLY B H    1 
ATOM   6854 H HA2  . GLY B 1 149 ? -21.41819 5.67238   -38.43920 1.000 39.12683  ? 149 GLY B HA2  1 
ATOM   6855 H HA3  . GLY B 1 149 ? -21.41551 4.94660   -39.84195 1.000 39.12683  ? 149 GLY B HA3  1 
ATOM   6856 N N    . PHE B 1 150 ? -19.13357 6.48607   -39.18734 1.000 29.69859  ? 150 PHE B N    1 
ATOM   6857 C CA   . PHE B 1 150 ? -18.07377 7.46146   -39.39194 1.000 30.68941  ? 150 PHE B CA   1 
ATOM   6858 C C    . PHE B 1 150 ? -16.75529 6.91594   -38.87325 1.000 29.13882  ? 150 PHE B C    1 
ATOM   6859 O O    . PHE B 1 150 ? -16.72491 6.07632   -37.97032 1.000 33.16190  ? 150 PHE B O    1 
ATOM   6860 C CB   . PHE B 1 150 ? -18.40517 8.78296   -38.68015 1.000 30.32457  ? 150 PHE B CB   1 
ATOM   6861 C CG   . PHE B 1 150 ? -18.43826 8.66481   -37.18142 1.000 29.69843  ? 150 PHE B CG   1 
ATOM   6862 C CD1  . PHE B 1 150 ? -19.55872 8.16269   -36.53798 1.000 30.70358  ? 150 PHE B CD1  1 
ATOM   6863 C CD2  . PHE B 1 150 ? -17.34413 9.04077   -36.41740 1.000 30.28763  ? 150 PHE B CD2  1 
ATOM   6864 C CE1  . PHE B 1 150 ? -19.59389 8.04059   -35.15594 1.000 34.14932  ? 150 PHE B CE1  1 
ATOM   6865 C CE2  . PHE B 1 150 ? -17.36879 8.92146   -35.03457 1.000 37.54517  ? 150 PHE B CE2  1 
ATOM   6866 C CZ   . PHE B 1 150 ? -18.49836 8.41983   -34.40261 1.000 38.89624  ? 150 PHE B CZ   1 
ATOM   6867 H H    . PHE B 1 150 ? -18.95160 5.84207   -38.64720 1.000 35.63208  ? 150 PHE B H    1 
ATOM   6868 H HA   . PHE B 1 150 ? -17.97159 7.61887   -40.34362 1.000 36.82106  ? 150 PHE B HA   1 
ATOM   6869 H HB2  . PHE B 1 150 ? -17.73080 9.44066   -38.91156 1.000 36.38325  ? 150 PHE B HB2  1 
ATOM   6870 H HB3  . PHE B 1 150 ? -19.27862 9.08597   -38.97369 1.000 36.38325  ? 150 PHE B HB3  1 
ATOM   6871 H HD1  . PHE B 1 150 ? -20.29772 7.90385   -37.03977 1.000 36.83807  ? 150 PHE B HD1  1 
ATOM   6872 H HD2  . PHE B 1 150 ? -16.58481 9.37682   -36.83621 1.000 36.33893  ? 150 PHE B HD2  1 
ATOM   6873 H HE1  . PHE B 1 150 ? -20.35313 7.70421   -34.73725 1.000 40.97295  ? 150 PHE B HE1  1 
ATOM   6874 H HE2  . PHE B 1 150 ? -16.62927 9.17734   -34.53204 1.000 45.04797  ? 150 PHE B HE2  1 
ATOM   6875 H HZ   . PHE B 1 150 ? -18.51813 8.33920   -33.47632 1.000 46.66927  ? 150 PHE B HZ   1 
ATOM   6876 N N    . ASN B 1 151 ? -15.67012 7.42176   -39.44796 1.000 33.05613  ? 151 ASN B N    1 
ATOM   6877 C CA   . ASN B 1 151 ? -14.32569 7.23220   -38.92956 1.000 42.23623  ? 151 ASN B CA   1 
ATOM   6878 C C    . ASN B 1 151 ? -13.73151 8.59562   -38.59431 1.000 40.26200  ? 151 ASN B C    1 
ATOM   6879 O O    . ASN B 1 151 ? -14.17734 9.62923   -39.10233 1.000 37.62461  ? 151 ASN B O    1 
ATOM   6880 C CB   . ASN B 1 151 ? -13.43980 6.49041   -39.94152 1.000 43.07731  ? 151 ASN B CB   1 
ATOM   6881 C CG   . ASN B 1 151 ? -13.81585 5.02483   -40.08096 1.000 34.49212  ? 151 ASN B CG   1 
ATOM   6882 O OD1  . ASN B 1 151 ? -14.52038 4.63130   -41.00922 1.000 39.29863  ? 151 ASN B OD1  1 
ATOM   6883 N ND2  . ASN B 1 151 ? -13.35190 4.21278   -39.14844 1.000 34.51052  ? 151 ASN B ND2  1 
ATOM   6884 H H    . ASN B 1 151 ? -15.69036 7.89542   -40.16548 1.000 39.66113  ? 151 ASN B H    1 
ATOM   6885 H HA   . ASN B 1 151 ? -14.34829 6.69956   -38.11920 1.000 50.67725  ? 151 ASN B HA   1 
ATOM   6886 H HB2  . ASN B 1 151 ? -13.53356 6.90909   -40.81147 1.000 51.68654  ? 151 ASN B HB2  1 
ATOM   6887 H HB3  . ASN B 1 151 ? -12.51631 6.53743   -39.64851 1.000 51.68654  ? 151 ASN B HB3  1 
ATOM   6888 H HD21 . ASN B 1 151 ? -13.53492 3.37307   -39.17961 1.000 41.40640  ? 151 ASN B HD21 1 
ATOM   6889 H HD22 . ASN B 1 151 ? -12.86675 4.52373   -38.51005 1.000 41.40640  ? 151 ASN B HD22 1 
ATOM   6890 N N    . ILE B 1 152 ? -12.72264 8.59901   -37.72470 1.000 37.53332  ? 152 ILE B N    1 
ATOM   6891 C CA   . ILE B 1 152 ? -12.01843 9.82324   -37.35533 1.000 47.17118  ? 152 ILE B CA   1 
ATOM   6892 C C    . ILE B 1 152 ? -10.54104 9.65091   -37.67866 1.000 45.78622  ? 152 ILE B C    1 
ATOM   6893 O O    . ILE B 1 152 ? -9.89118  8.72387   -37.17804 1.000 46.94028  ? 152 ILE B O    1 
ATOM   6894 C CB   . ILE B 1 152 ? -12.21849 10.18549  -35.87516 1.000 46.88888  ? 152 ILE B CB   1 
ATOM   6895 C CG1  . ILE B 1 152 ? -13.71502 10.26560  -35.55921 1.000 39.10975  ? 152 ILE B CG1  1 
ATOM   6896 C CG2  . ILE B 1 152 ? -11.52970 11.51403  -35.56386 1.000 41.93101  ? 152 ILE B CG2  1 
ATOM   6897 C CD1  . ILE B 1 152 ? -14.04228 10.90198  -34.22341 1.000 49.28784  ? 152 ILE B CD1  1 
ATOM   6898 H H    . ILE B 1 152 ? -12.42524 7.89454   -37.33117 1.000 45.03376  ? 152 ILE B H    1 
ATOM   6899 H HA   . ILE B 1 152 ? -12.36070 10.55186  -37.89650 1.000 56.59918  ? 152 ILE B HA   1 
ATOM   6900 H HB   . ILE B 1 152 ? -11.82065 9.49500   -35.32213 1.000 56.26042  ? 152 ILE B HB   1 
ATOM   6901 H HG12 . ILE B 1 152 ? -14.14858 10.79247  -36.24865 1.000 46.92547  ? 152 ILE B HG12 1 
ATOM   6902 H HG13 . ILE B 1 152 ? -14.07781 9.36603   -35.55176 1.000 46.92547  ? 152 ILE B HG13 1 
ATOM   6903 H HG21 . ILE B 1 152 ? -10.60065 11.45979  -35.83741 1.000 50.31098  ? 152 ILE B HG21 1 
ATOM   6904 H HG22 . ILE B 1 152 ? -11.97710 12.22350  -36.05109 1.000 50.31098  ? 152 ILE B HG22 1 
ATOM   6905 H HG23 . ILE B 1 152 ? -11.58441 11.68226  -34.61013 1.000 50.31098  ? 152 ILE B HG23 1 
ATOM   6906 H HD11 . ILE B 1 152 ? -13.85154 11.85185  -34.27094 1.000 59.13918  ? 152 ILE B HD11 1 
ATOM   6907 H HD12 . ILE B 1 152 ? -14.98235 10.76269  -34.02910 1.000 59.13918  ? 152 ILE B HD12 1 
ATOM   6908 H HD13 . ILE B 1 152 ? -13.49754 10.48925  -33.53507 1.000 59.13918  ? 152 ILE B HD13 1 
ATOM   6909 N N    . ASP B 1 153 ? -10.01806 10.54747  -38.51506 1.000 50.90324  ? 153 ASP B N    1 
ATOM   6910 C CA   . ASP B 1 153 ? -8.60407  10.60200  -38.88130 1.000 52.13734  ? 153 ASP B CA   1 
ATOM   6911 C C    . ASP B 1 153 ? -8.00554  11.82175  -38.18655 1.000 53.66954  ? 153 ASP B C    1 
ATOM   6912 O O    . ASP B 1 153 ? -8.08110  12.94200  -38.69952 1.000 51.55291  ? 153 ASP B O    1 
ATOM   6913 C CB   . ASP B 1 153 ? -8.43701  10.67644  -40.39587 1.000 58.10928  ? 153 ASP B CB   1 
ATOM   6914 C CG   . ASP B 1 153 ? -7.02901  11.06325  -40.81247 1.000 77.20717  ? 153 ASP B CG   1 
ATOM   6915 O OD1  . ASP B 1 153 ? -6.08575  10.86216  -40.01568 1.000 75.21361  ? 153 ASP B OD1  1 
ATOM   6916 O OD2  . ASP B 1 153 ? -6.86881  11.57986  -41.93893 1.000 80.05982  ? 153 ASP B OD2  1 
ATOM   6917 H H    . ASP B 1 153 ? -10.48344 11.16031  -38.89905 1.000 61.07766  ? 153 ASP B H    1 
ATOM   6918 H HA   . ASP B 1 153 ? -8.14862  9.80535   -38.56697 1.000 62.55858  ? 153 ASP B HA   1 
ATOM   6919 H HB2  . ASP B 1 153 ? -8.63526  9.80762   -40.77894 1.000 69.72491  ? 153 ASP B HB2  1 
ATOM   6920 H HB3  . ASP B 1 153 ? -9.04793  11.34197  -40.74905 1.000 69.72491  ? 153 ASP B HB3  1 
ATOM   6921 N N    . TYR B 1 154 ? -7.40845  11.59454  -37.01904 1.000 52.60874  ? 154 TYR B N    1 
ATOM   6922 C CA   . TYR B 1 154 ? -6.91140  12.67122  -36.17199 1.000 53.68440  ? 154 TYR B CA   1 
ATOM   6923 C C    . TYR B 1 154 ? -8.03530  13.63187  -35.80024 1.000 55.72868  ? 154 TYR B C    1 
ATOM   6924 O O    . TYR B 1 154 ? -8.64254  13.49794  -34.73308 1.000 56.34601  ? 154 TYR B O    1 
ATOM   6925 C CB   . TYR B 1 154 ? -5.77081  13.43090  -36.85489 1.000 62.43039  ? 154 TYR B CB   1 
ATOM   6926 C CG   . TYR B 1 154 ? -5.28821  14.61663  -36.04582 1.000 61.20414  ? 154 TYR B CG   1 
ATOM   6927 C CD1  . TYR B 1 154 ? -5.08802  14.50807  -34.67447 1.000 72.81250  ? 154 TYR B CD1  1 
ATOM   6928 C CD2  . TYR B 1 154 ? -5.03812  15.84306  -36.64797 1.000 60.97551  ? 154 TYR B CD2  1 
ATOM   6929 C CE1  . TYR B 1 154 ? -4.65386  15.58770  -33.92443 1.000 80.23000  ? 154 TYR B CE1  1 
ATOM   6930 C CE2  . TYR B 1 154 ? -4.59949  16.92970  -35.90562 1.000 76.05752  ? 154 TYR B CE2  1 
ATOM   6931 C CZ   . TYR B 1 154 ? -4.40985  16.79557  -34.54461 1.000 78.02327  ? 154 TYR B CZ   1 
ATOM   6932 O OH   . TYR B 1 154 ? -3.97669  17.86983  -33.80031 1.000 76.83231  ? 154 TYR B OH   1 
ATOM   6933 H H    . TYR B 1 154 ? -7.27730  10.81078  -36.69022 1.000 63.12426  ? 154 TYR B H    1 
ATOM   6934 H HA   . TYR B 1 154 ? -6.55955  12.28142  -35.35642 1.000 64.41505  ? 154 TYR B HA   1 
ATOM   6935 H HB2  . TYR B 1 154 ? -5.02118  12.82829  -36.98067 1.000 74.91024  ? 154 TYR B HB2  1 
ATOM   6936 H HB3  . TYR B 1 154 ? -6.08012  13.75937  -37.71358 1.000 74.91024  ? 154 TYR B HB3  1 
ATOM   6937 H HD1  . TYR B 1 154 ? -5.24877  13.69484  -34.25291 1.000 87.36878  ? 154 TYR B HD1  1 
ATOM   6938 H HD2  . TYR B 1 154 ? -5.16689  15.93729  -37.56418 1.000 73.16439  ? 154 TYR B HD2  1 
ATOM   6939 H HE1  . TYR B 1 154 ? -4.52738  15.49914  -33.00733 1.000 96.26977  ? 154 TYR B HE1  1 
ATOM   6940 H HE2  . TYR B 1 154 ? -4.43401  17.74438  -36.32254 1.000 91.26280  ? 154 TYR B HE2  1 
ATOM   6941 H HH   . TYR B 1 154 ? -3.90104  18.54745  -34.29092 1.000 92.19255  ? 154 TYR B HH   1 
ATOM   6942 N N    . ASP B 1 155 ? -8.32015  14.60161  -36.67018 1.000 55.05606  ? 155 ASP B N    1 
ATOM   6943 C CA   . ASP B 1 155 ? -9.33648  15.60900  -36.40231 1.000 59.20741  ? 155 ASP B CA   1 
ATOM   6944 C C    . ASP B 1 155 ? -10.41207 15.67820  -37.47651 1.000 50.41962  ? 155 ASP B C    1 
ATOM   6945 O O    . ASP B 1 155 ? -11.35922 16.46139  -37.33406 1.000 46.36832  ? 155 ASP B O    1 
ATOM   6946 C CB   . ASP B 1 155 ? -8.68584  16.99133  -36.25422 1.000 62.69503  ? 155 ASP B CB   1 
ATOM   6947 C CG   . ASP B 1 155 ? -8.11223  17.50910  -37.55915 1.000 61.07386  ? 155 ASP B CG   1 
ATOM   6948 O OD1  . ASP B 1 155 ? -7.82702  16.69007  -38.45909 1.000 58.98078  ? 155 ASP B OD1  1 
ATOM   6949 O OD2  . ASP B 1 155 ? -7.94498  18.73948  -37.68179 1.000 70.34623  ? 155 ASP B OD2  1 
ATOM   6950 H H    . ASP B 1 155 ? -7.93118  14.69523  -37.43145 1.000 66.06105  ? 155 ASP B H    1 
ATOM   6951 H HA   . ASP B 1 155 ? -9.77015  15.38856  -35.56313 1.000 71.04266  ? 155 ASP B HA   1 
ATOM   6952 H HB2  . ASP B 1 155 ? -9.35370  17.62435  -35.94741 1.000 75.22780  ? 155 ASP B HB2  1 
ATOM   6953 H HB3  . ASP B 1 155 ? -7.96285  16.93357  -35.61012 1.000 75.22780  ? 155 ASP B HB3  1 
ATOM   6954 N N    . CYS B 1 156 ? -10.29770 14.88960  -38.53940 1.000 48.87196  ? 156 CYS B N    1 
ATOM   6955 C CA   . CYS B 1 156 ? -11.24458 14.91304  -39.64463 1.000 46.60271  ? 156 CYS B CA   1 
ATOM   6956 C C    . CYS B 1 156 ? -12.22814 13.75949  -39.49404 1.000 44.13517  ? 156 CYS B C    1 
ATOM   6957 O O    . CYS B 1 156 ? -11.82084 12.61123  -39.28719 1.000 42.17642  ? 156 CYS B O    1 
ATOM   6958 C CB   . CYS B 1 156 ? -10.50847 14.82103  -40.98204 1.000 41.42052  ? 156 CYS B CB   1 
ATOM   6959 S SG   . CYS B 1 156 ? -11.56398 15.02113  -42.43210 1.000 58.20256  ? 156 CYS B SG   1 
ATOM   6960 H H    . CYS B 1 156 ? -9.66336  14.31850  -38.64460 1.000 58.64012  ? 156 CYS B H    1 
ATOM   6961 H HA   . CYS B 1 156 ? -11.74797 15.74208  -39.63108 1.000 55.91702  ? 156 CYS B HA   1 
ATOM   6962 H HB2  . CYS B 1 156 ? -9.83410  15.51761  -41.01199 1.000 49.69840  ? 156 CYS B HB2  1 
ATOM   6963 H HB3  . CYS B 1 156 ? -10.08782 13.94917  -41.04375 1.000 49.69840  ? 156 CYS B HB3  1 
ATOM   6964 H HG   . CYS B 1 156 ? -12.07862 16.10451  -42.39421 1.000 69.83684  ? 156 CYS B HG   1 
ATOM   6965 N N    . VAL B 1 157 ? -13.51741 14.07063  -39.58333 1.000 39.65414  ? 157 VAL B N    1 
ATOM   6966 C CA   . VAL B 1 157 ? -14.56627 13.06158  -39.50774 1.000 44.83000  ? 157 VAL B CA   1 
ATOM   6967 C C    . VAL B 1 157 ? -14.92549 12.64735  -40.92706 1.000 34.73482  ? 157 VAL B C    1 
ATOM   6968 O O    . VAL B 1 157 ? -15.44180 13.45569  -41.70629 1.000 35.23820  ? 157 VAL B O    1 
ATOM   6969 C CB   . VAL B 1 157 ? -15.80409 13.58878  -38.76163 1.000 42.28783  ? 157 VAL B CB   1 
ATOM   6970 C CG1  . VAL B 1 157 ? -16.86598 12.49125  -38.66874 1.000 38.51454  ? 157 VAL B CG1  1 
ATOM   6971 C CG2  . VAL B 1 157 ? -15.42229 14.10598  -37.37784 1.000 34.33176  ? 157 VAL B CG2  1 
ATOM   6972 H H    . VAL B 1 157 ? -13.81326 14.87114  -39.68945 1.000 47.57874  ? 157 VAL B H    1 
ATOM   6973 H HA   . VAL B 1 157 ? -14.23084 12.28730  -39.02934 1.000 53.78978  ? 157 VAL B HA   1 
ATOM   6974 H HB   . VAL B 1 157 ? -16.18127 14.33375  -39.25524 1.000 50.73916  ? 157 VAL B HB   1 
ATOM   6975 H HG11 . VAL B 1 157 ? -16.44501 11.63080  -38.82146 1.000 46.21122  ? 157 VAL B HG11 1 
ATOM   6976 H HG12 . VAL B 1 157 ? -17.26512 12.51200  -37.78492 1.000 46.21122  ? 157 VAL B HG12 1 
ATOM   6977 H HG13 . VAL B 1 157 ? -17.54534 12.65131  -39.34234 1.000 46.21122  ? 157 VAL B HG13 1 
ATOM   6978 H HG21 . VAL B 1 157 ? -16.23124 14.29202  -36.87596 1.000 41.19188  ? 157 VAL B HG21 1 
ATOM   6979 H HG22 . VAL B 1 157 ? -14.89806 13.42942  -36.92140 1.000 41.19188  ? 157 VAL B HG22 1 
ATOM   6980 H HG23 . VAL B 1 157 ? -14.90049 14.91765  -37.47697 1.000 41.19188  ? 157 VAL B HG23 1 
ATOM   6981 N N    . SER B 1 158 ? -14.66121 11.38805  -41.26521 1.000 42.66440  ? 158 SER B N    1 
ATOM   6982 C CA   . SER B 1 158 ? -15.03002 10.81844  -42.55619 1.000 41.04279  ? 158 SER B CA   1 
ATOM   6983 C C    . SER B 1 158 ? -16.36536 10.10024  -42.38210 1.000 34.73231  ? 158 SER B C    1 
ATOM   6984 O O    . SER B 1 158 ? -16.42695 9.03206   -41.76303 1.000 35.39849  ? 158 SER B O    1 
ATOM   6985 C CB   . SER B 1 158 ? -13.94619 9.87040   -43.07054 1.000 38.43571  ? 158 SER B CB   1 
ATOM   6986 O OG   . SER B 1 158 ? -12.76309 10.57439  -43.41251 1.000 47.93535  ? 158 SER B OG   1 
ATOM   6987 H H    . SER B 1 158 ? -14.25846 10.83025  -40.74920 1.000 51.19105  ? 158 SER B H    1 
ATOM   6988 H HA   . SER B 1 158 ? -15.13651 11.52620  -43.21090 1.000 49.24512  ? 158 SER B HA   1 
ATOM   6989 H HB2  . SER B 1 158 ? -13.73798 9.22589   -42.37615 1.000 46.11662  ? 158 SER B HB2  1 
ATOM   6990 H HB3  . SER B 1 158 ? -14.27797 9.41305   -43.85899 1.000 46.11662  ? 158 SER B HB3  1 
ATOM   6991 H HG   . SER B 1 158 ? -12.28196 10.10157  -43.91306 1.000 57.51620  ? 158 SER B HG   1 
ATOM   6992 N N    . PHE B 1 159 ? -17.43233 10.70057  -42.90147 1.000 32.56690  ? 159 PHE B N    1 
ATOM   6993 C CA   . PHE B 1 159 ? -18.74967 10.08106  -42.87011 1.000 31.17661  ? 159 PHE B CA   1 
ATOM   6994 C C    . PHE B 1 159 ? -18.87078 9.08431   -44.01443 1.000 31.21248  ? 159 PHE B C    1 
ATOM   6995 O O    . PHE B 1 159 ? -18.65023 9.43600   -45.17776 1.000 38.59958  ? 159 PHE B O    1 
ATOM   6996 C CB   . PHE B 1 159 ? -19.84815 11.13806  -42.98431 1.000 31.45217  ? 159 PHE B CB   1 
ATOM   6997 C CG   . PHE B 1 159 ? -19.88611 12.10583  -41.84032 1.000 29.82816  ? 159 PHE B CG   1 
ATOM   6998 C CD1  . PHE B 1 159 ? -20.41749 11.73099  -40.61866 1.000 33.60260  ? 159 PHE B CD1  1 
ATOM   6999 C CD2  . PHE B 1 159 ? -19.40739 13.39563  -41.99149 1.000 34.88355  ? 159 PHE B CD2  1 
ATOM   7000 C CE1  . PHE B 1 159 ? -20.46028 12.61988  -39.56269 1.000 30.35142  ? 159 PHE B CE1  1 
ATOM   7001 C CE2  . PHE B 1 159 ? -19.44956 14.29213  -40.94159 1.000 33.49937  ? 159 PHE B CE2  1 
ATOM   7002 C CZ   . PHE B 1 159 ? -19.97823 13.90307  -39.72453 1.000 38.98583  ? 159 PHE B CZ   1 
ATOM   7003 H H    . PHE B 1 159 ? -17.41805 11.47260  -43.28010 1.000 39.07405  ? 159 PHE B H    1 
ATOM   7004 H HA   . PHE B 1 159 ? -18.86584 9.61477   -42.02751 1.000 37.40570  ? 159 PHE B HA   1 
ATOM   7005 H HB2  . PHE B 1 159 ? -19.70550 11.64789  -43.79710 1.000 37.73637  ? 159 PHE B HB2  1 
ATOM   7006 H HB3  . PHE B 1 159 ? -20.70781 10.69019  -43.02018 1.000 37.73637  ? 159 PHE B HB3  1 
ATOM   7007 H HD1  . PHE B 1 159 ? -20.74995 10.86959  -40.50746 1.000 40.31689  ? 159 PHE B HD1  1 
ATOM   7008 H HD2  . PHE B 1 159 ? -19.05330 13.66169  -42.80925 1.000 41.85404  ? 159 PHE B HD2  1 
ATOM   7009 H HE1  . PHE B 1 159 ? -20.81316 12.35446  -38.74420 1.000 36.41547  ? 159 PHE B HE1  1 
ATOM   7010 H HE2  . PHE B 1 159 ? -19.12303 15.15576  -41.05300 1.000 40.19302  ? 159 PHE B HE2  1 
ATOM   7011 H HZ   . PHE B 1 159 ? -20.00894 14.50498  -39.01624 1.000 46.77677  ? 159 PHE B HZ   1 
ATOM   7012 N N    . CYS B 1 160 ? -19.23439 7.84321   -43.68438 1.000 32.62979  ? 160 CYS B N    1 
ATOM   7013 C CA   . CYS B 1 160 ? -19.32849 6.77837   -44.67038 1.000 30.44781  ? 160 CYS B CA   1 
ATOM   7014 C C    . CYS B 1 160 ? -20.68509 6.09764   -44.71862 1.000 32.25512  ? 160 CYS B C    1 
ATOM   7015 O O    . CYS B 1 160 ? -20.92953 5.31834   -45.64723 1.000 34.39693  ? 160 CYS B O    1 
ATOM   7016 C CB   . CYS B 1 160 ? -18.26266 5.70375   -44.40353 1.000 28.83504  ? 160 CYS B CB   1 
ATOM   7017 S SG   . CYS B 1 160 ? -18.36477 4.92930   -42.77303 1.000 37.82771  ? 160 CYS B SG   1 
ATOM   7018 H H    . CYS B 1 160 ? -19.43289 7.59536   -42.88515 1.000 39.14951  ? 160 CYS B H    1 
ATOM   7019 H HA   . CYS B 1 160 ? -19.15887 7.16523   -45.54358 1.000 36.53114  ? 160 CYS B HA   1 
ATOM   7020 H HB2  . CYS B 1 160 ? -18.35899 5.00261   -45.06687 1.000 34.59583  ? 160 CYS B HB2  1 
ATOM   7021 H HB3  . CYS B 1 160 ? -17.38653 6.11323   -44.47845 1.000 34.59583  ? 160 CYS B HB3  1 
ATOM   7022 H HG   . CYS B 1 160 ? -19.40944 4.34582   -42.68239 1.000 45.38703  ? 160 CYS B HG   1 
ATOM   7023 N N    . TYR B 1 161 ? -21.57031 6.35863   -43.76175 1.000 33.66446  ? 161 TYR B N    1 
ATOM   7024 C CA   . TYR B 1 161 ? -22.81281 5.60968   -43.68193 1.000 33.47289  ? 161 TYR B CA   1 
ATOM   7025 C C    . TYR B 1 161 ? -23.91331 6.48323   -43.10942 1.000 28.52991  ? 161 TYR B C    1 
ATOM   7026 O O    . TYR B 1 161 ? -23.68417 7.26271   -42.18243 1.000 29.83153  ? 161 TYR B O    1 
ATOM   7027 C CB   . TYR B 1 161 ? -22.64033 4.35543   -42.81722 1.000 29.70757  ? 161 TYR B CB   1 
ATOM   7028 C CG   . TYR B 1 161 ? -23.86263 3.47320   -42.74977 1.000 28.74127  ? 161 TYR B CG   1 
ATOM   7029 C CD1  . TYR B 1 161 ? -24.15227 2.57607   -43.77024 1.000 33.52037  ? 161 TYR B CD1  1 
ATOM   7030 C CD2  . TYR B 1 161 ? -24.72026 3.52650   -41.66045 1.000 25.84190  ? 161 TYR B CD2  1 
ATOM   7031 C CE1  . TYR B 1 161 ? -25.26792 1.75970   -43.71056 1.000 34.28888  ? 161 TYR B CE1  1 
ATOM   7032 C CE2  . TYR B 1 161 ? -25.83997 2.71415   -41.58959 1.000 24.31163  ? 161 TYR B CE2  1 
ATOM   7033 C CZ   . TYR B 1 161 ? -26.10828 1.83506   -42.61986 1.000 34.28909  ? 161 TYR B CZ   1 
ATOM   7034 O OH   . TYR B 1 161 ? -27.21336 1.02149   -42.56619 1.000 29.92082  ? 161 TYR B OH   1 
ATOM   7035 H H    . TYR B 1 161 ? -21.47257 6.95945   -43.15424 1.000 40.39113  ? 161 TYR B H    1 
ATOM   7036 H HA   . TYR B 1 161 ? -23.08255 5.34753   -44.57603 1.000 40.16124  ? 161 TYR B HA   1 
ATOM   7037 H HB2  . TYR B 1 161 ? -21.91518 3.82485   -43.18265 1.000 35.64285  ? 161 TYR B HB2  1 
ATOM   7038 H HB3  . TYR B 1 161 ? -22.42661 4.63056   -41.91195 1.000 35.64285  ? 161 TYR B HB3  1 
ATOM   7039 H HD1  . TYR B 1 161 ? -23.58640 2.52327   -44.50638 1.000 40.21821  ? 161 TYR B HD1  1 
ATOM   7040 H HD2  . TYR B 1 161 ? -24.54022 4.11797   -40.96572 1.000 31.00405  ? 161 TYR B HD2  1 
ATOM   7041 H HE1  . TYR B 1 161 ? -25.44976 1.16422   -44.40138 1.000 41.14043  ? 161 TYR B HE1  1 
ATOM   7042 H HE2  . TYR B 1 161 ? -26.40668 2.76053   -40.85367 1.000 29.16772  ? 161 TYR B HE2  1 
ATOM   7043 H HH   . TYR B 1 161 ? -27.14587 0.40732   -43.13525 1.000 35.89876  ? 161 TYR B HH   1 
ATOM   7044 N N    . MET B 1 162 ? -25.10303 6.34826   -43.68310 1.000 33.82612  ? 162 MET B N    1 
ATOM   7045 C CA   . MET B 1 162 ? -26.33535 6.87793   -43.11696 1.000 36.23625  ? 162 MET B CA   1 
ATOM   7046 C C    . MET B 1 162 ? -27.36142 5.75539   -43.17406 1.000 33.53010  ? 162 MET B C    1 
ATOM   7047 O O    . MET B 1 162 ? -27.49893 5.09282   -44.20764 1.000 32.94374  ? 162 MET B O    1 
ATOM   7048 C CB   . MET B 1 162 ? -26.81838 8.11930   -43.87634 1.000 32.49209  ? 162 MET B CB   1 
ATOM   7049 C CG   . MET B 1 162 ? -28.25414 8.52276   -43.56185 1.000 32.90208  ? 162 MET B CG   1 
ATOM   7050 S SD   . MET B 1 162 ? -28.68860 10.15805  -44.18051 1.000 39.24822  ? 162 MET B SD   1 
ATOM   7051 C CE   . MET B 1 162 ? -27.91502 11.19891  -42.94351 1.000 32.59076  ? 162 MET B CE   1 
ATOM   7052 H H    . MET B 1 162 ? -25.22572 5.93813   -44.42898 1.000 40.58511  ? 162 MET B H    1 
ATOM   7053 H HA   . MET B 1 162 ? -26.20216 7.15927   -42.19826 1.000 43.47727  ? 162 MET B HA   1 
ATOM   7054 H HB2  . MET B 1 162 ? -26.24507 8.86691   -43.64549 1.000 38.98428  ? 162 MET B HB2  1 
ATOM   7055 H HB3  . MET B 1 162 ? -26.76425 7.94131   -44.82833 1.000 38.98428  ? 162 MET B HB3  1 
ATOM   7056 H HG2  . MET B 1 162 ? -28.85674 7.88097   -43.96912 1.000 39.47627  ? 162 MET B HG2  1 
ATOM   7057 H HG3  . MET B 1 162 ? -28.37517 8.52708   -42.59944 1.000 39.47627  ? 162 MET B HG3  1 
ATOM   7058 H HE1  . MET B 1 162 ? -27.76486 10.67638  -42.14020 1.000 39.10268  ? 162 MET B HE1  1 
ATOM   7059 H HE2  . MET B 1 162 ? -27.06925 11.52475  -43.28906 1.000 39.10268  ? 162 MET B HE2  1 
ATOM   7060 H HE3  . MET B 1 162 ? -28.50200 11.94582  -42.74737 1.000 39.10268  ? 162 MET B HE3  1 
ATOM   7061 N N    . HIS B 1 163 ? -28.05300 5.51907   -42.06238 1.000 33.39788  ? 163 HIS B N    1 
ATOM   7062 C CA   . HIS B 1 163 ? -28.92105 4.35558   -41.95374 1.000 31.63654  ? 163 HIS B CA   1 
ATOM   7063 C C    . HIS B 1 163 ? -30.28519 4.61537   -42.57703 1.000 31.34783  ? 163 HIS B C    1 
ATOM   7064 O O    . HIS B 1 163 ? -30.86591 5.69098   -42.41032 1.000 35.22602  ? 163 HIS B O    1 
ATOM   7065 C CB   . HIS B 1 163 ? -29.10434 3.95787   -40.49305 1.000 31.46071  ? 163 HIS B CB   1 
ATOM   7066 C CG   . HIS B 1 163 ? -30.03058 2.79988   -40.30704 1.000 37.12847  ? 163 HIS B CG   1 
ATOM   7067 N ND1  . HIS B 1 163 ? -29.76086 1.54643   -40.81212 1.000 31.38133  ? 163 HIS B ND1  1 
ATOM   7068 C CD2  . HIS B 1 163 ? -31.23464 2.70894   -39.69541 1.000 32.69067  ? 163 HIS B CD2  1 
ATOM   7069 C CE1  . HIS B 1 163 ? -30.75323 0.72979   -40.50750 1.000 37.56585  ? 163 HIS B CE1  1 
ATOM   7070 N NE2  . HIS B 1 163 ? -31.65853 1.40924   -39.82713 1.000 39.44442  ? 163 HIS B NE2  1 
ATOM   7071 H H    . HIS B 1 163 ? -28.03555 6.01644   -41.36101 1.000 40.07123  ? 163 HIS B H    1 
ATOM   7072 H HA   . HIS B 1 163 ? -28.50594 3.62052   -42.43151 1.000 37.95762  ? 163 HIS B HA   1 
ATOM   7073 H HB2  . HIS B 1 163 ? -28.24158 3.71146   -40.12451 1.000 37.74663  ? 163 HIS B HB2  1 
ATOM   7074 H HB3  . HIS B 1 163 ? -29.46978 4.71291   -40.00595 1.000 37.74663  ? 163 HIS B HB3  1 
ATOM   7075 H HD2  . HIS B 1 163 ? -31.68955 3.39739   -39.26646 1.000 39.22258  ? 163 HIS B HD2  1 
ATOM   7076 H HE1  . HIS B 1 163 ? -30.80558 -0.17076  -40.73371 1.000 45.07279  ? 163 HIS B HE1  1 
ATOM   7077 H HE2  . HIS B 1 163 ? -32.39420 1.08967   -39.51686 1.000 47.32707  ? 163 HIS B HE2  1 
ATOM   7078 N N    . HIS B 1 164 ? -30.80938 3.60573   -43.27095 1.000 36.74313  ? 164 HIS B N    1 
ATOM   7079 C CA   . HIS B 1 164 ? -32.08644 3.72051   -43.96572 1.000 39.33019  ? 164 HIS B CA   1 
ATOM   7080 C C    . HIS B 1 164 ? -33.11430 2.67703   -43.56113 1.000 32.58795  ? 164 HIS B C    1 
ATOM   7081 O O    . HIS B 1 164 ? -34.27420 3.02852   -43.34499 1.000 44.60477  ? 164 HIS B O    1 
ATOM   7082 C CB   . HIS B 1 164 ? -31.86792 3.63937   -45.48249 1.000 31.02043  ? 164 HIS B CB   1 
ATOM   7083 C CG   . HIS B 1 164 ? -31.32959 4.90074   -46.07710 1.000 35.29874  ? 164 HIS B CG   1 
ATOM   7084 N ND1  . HIS B 1 164 ? -32.08837 5.72846   -46.87559 1.000 37.06396  ? 164 HIS B ND1  1 
ATOM   7085 C CD2  . HIS B 1 164 ? -30.11397 5.48844   -45.97243 1.000 35.90595  ? 164 HIS B CD2  1 
ATOM   7086 C CE1  . HIS B 1 164 ? -31.35964 6.76564   -47.24834 1.000 34.86112  ? 164 HIS B CE1  1 
ATOM   7087 N NE2  . HIS B 1 164 ? -30.15888 6.64629   -46.71046 1.000 34.41307  ? 164 HIS B NE2  1 
ATOM   7088 H H    . HIS B 1 164 ? -30.43744 2.83476   -43.35386 1.000 44.08552  ? 164 HIS B H    1 
ATOM   7089 H HA   . HIS B 1 164 ? -32.46195 4.58908   -43.75248 1.000 47.19000  ? 164 HIS B HA   1 
ATOM   7090 H HB2  . HIS B 1 164 ? -31.23439 2.92904   -45.66950 1.000 37.21829  ? 164 HIS B HB2  1 
ATOM   7091 H HB3  . HIS B 1 164 ? -32.71691 3.44798   -45.91085 1.000 37.21829  ? 164 HIS B HB3  1 
ATOM   7092 H HD1  . HIS B 1 164 ? -32.90807 5.59143   -47.09676 1.000 44.47052  ? 164 HIS B HD1  1 
ATOM   7093 H HD2  . HIS B 1 164 ? -29.38541 5.16825   -45.49119 1.000 43.08091  ? 164 HIS B HD2  1 
ATOM   7094 H HE1  . HIS B 1 164 ? -31.64367 7.46139   -47.79619 1.000 41.82712  ? 164 HIS B HE1  1 
ATOM   7095 N N    . MET B 1 165 ? -32.73459 1.40736   -43.44313 1.000 34.35451  ? 165 MET B N    1 
ATOM   7096 C CA   . MET B 1 165 ? -33.72764 0.34796   -43.33336 1.000 35.20612  ? 165 MET B CA   1 
ATOM   7097 C C    . MET B 1 165 ? -33.10111 -0.89518  -42.71924 1.000 40.03457  ? 165 MET B C    1 
ATOM   7098 O O    . MET B 1 165 ? -31.87831 -1.02139  -42.61880 1.000 37.18133  ? 165 MET B O    1 
ATOM   7099 C CB   . MET B 1 165 ? -34.31496 0.01836   -44.70878 1.000 43.66628  ? 165 MET B CB   1 
ATOM   7100 C CG   . MET B 1 165 ? -33.27184 -0.48770  -45.69499 1.000 40.04760  ? 165 MET B CG   1 
ATOM   7101 S SD   . MET B 1 165 ? -33.81736 -0.36995  -47.40812 1.000 55.38052  ? 165 MET B SD   1 
ATOM   7102 C CE   . MET B 1 165 ? -34.74685 -1.88879  -47.57999 1.000 53.77567  ? 165 MET B CE   1 
ATOM   7103 H H    . MET B 1 165 ? -31.91771 1.13908   -43.42457 1.000 41.21918  ? 165 MET B H    1 
ATOM   7104 H HA   . MET B 1 165 ? -34.43193 0.65541   -42.74146 1.000 42.24111  ? 165 MET B HA   1 
ATOM   7105 H HB2  . MET B 1 165 ? -34.98925 -0.67132  -44.60602 1.000 52.39331  ? 165 MET B HB2  1 
ATOM   7106 H HB3  . MET B 1 165 ? -34.71450 0.82017   -45.08076 1.000 52.39331  ? 165 MET B HB3  1 
ATOM   7107 H HG2  . MET B 1 165 ? -32.46439 0.04141   -45.60027 1.000 48.05089  ? 165 MET B HG2  1 
ATOM   7108 H HG3  . MET B 1 165 ? -33.08214 -1.41959  -45.50397 1.000 48.05089  ? 165 MET B HG3  1 
ATOM   7109 H HE1  . MET B 1 165 ? -34.20752 -2.53649  -48.06010 1.000 64.52457  ? 165 MET B HE1  1 
ATOM   7110 H HE2  . MET B 1 165 ? -34.96353 -2.22802  -46.69745 1.000 64.52457  ? 165 MET B HE2  1 
ATOM   7111 H HE3  . MET B 1 165 ? -35.56176 -1.70621  -48.07344 1.000 64.52457  ? 165 MET B HE3  1 
ATOM   7112 N N    . GLU B 1 166 ? -33.97054 -1.82590  -42.32850 1.000 41.02782  ? 166 GLU B N    1 
ATOM   7113 C CA   . GLU B 1 166 ? -33.58591 -3.12268  -41.78902 1.000 42.32100  ? 166 GLU B CA   1 
ATOM   7114 C C    . GLU B 1 166 ? -34.11221 -4.21423  -42.70893 1.000 40.91604  ? 166 GLU B C    1 
ATOM   7115 O O    . GLU B 1 166 ? -35.26621 -4.16432  -43.14054 1.000 44.88428  ? 166 GLU B O    1 
ATOM   7116 C CB   . GLU B 1 166 ? -34.13918 -3.31059  -40.37088 1.000 39.08938  ? 166 GLU B CB   1 
ATOM   7117 C CG   . GLU B 1 166 ? -34.12764 -4.74797  -39.86669 1.000 40.86879  ? 166 GLU B CG   1 
ATOM   7118 C CD   . GLU B 1 166 ? -34.58475 -4.85597  -38.42406 1.000 45.58131  ? 166 GLU B CD   1 
ATOM   7119 O OE1  . GLU B 1 166 ? -34.27318 -3.94231  -37.63061 1.000 42.21900  ? 166 GLU B OE1  1 
ATOM   7120 O OE2  . GLU B 1 166 ? -35.26472 -5.84724  -38.08624 1.000 50.85778  ? 166 GLU B OE2  1 
ATOM   7121 H H    . GLU B 1 166 ? -34.82327 -1.72201  -42.36919 1.000 49.22715  ? 166 GLU B H    1 
ATOM   7122 H HA   . GLU B 1 166 ? -32.61973 -3.19661  -41.74487 1.000 50.77898  ? 166 GLU B HA   1 
ATOM   7123 H HB2  . GLU B 1 166 ? -33.60326 -2.78233  -39.75881 1.000 46.90103  ? 166 GLU B HB2  1 
ATOM   7124 H HB3  . GLU B 1 166 ? -35.05918 -3.00353  -40.35614 1.000 46.90103  ? 166 GLU B HB3  1 
ATOM   7125 H HG2  . GLU B 1 166 ? -34.72548 -5.28137  -40.41348 1.000 49.03632  ? 166 GLU B HG2  1 
ATOM   7126 H HG3  . GLU B 1 166 ? -33.22472 -5.09771  -39.92420 1.000 49.03632  ? 166 GLU B HG3  1 
ATOM   7127 N N    . LEU B 1 167 ? -33.26285 -5.20324  -43.00581 1.000 49.53413  ? 167 LEU B N    1 
ATOM   7128 C CA   . LEU B 1 167 ? -33.61144 -6.29619  -43.90219 1.000 49.36353  ? 167 LEU B CA   1 
ATOM   7129 C C    . LEU B 1 167 ? -34.16817 -7.48025  -43.12290 1.000 57.20693  ? 167 LEU B C    1 
ATOM   7130 O O    . LEU B 1 167 ? -33.95040 -7.60068  -41.91330 1.000 52.55046  ? 167 LEU B O    1 
ATOM   7131 C CB   . LEU B 1 167 ? -32.38427 -6.73077  -44.69954 1.000 48.17503  ? 167 LEU B CB   1 
ATOM   7132 C CG   . LEU B 1 167 ? -31.73402 -5.64620  -45.56028 1.000 46.05525  ? 167 LEU B CG   1 
ATOM   7133 C CD1  . LEU B 1 167 ? -30.51646 -6.19208  -46.29051 1.000 52.99646  ? 167 LEU B CD1  1 
ATOM   7134 C CD2  . LEU B 1 167 ? -32.73758 -5.06220  -46.54721 1.000 43.88598  ? 167 LEU B CD2  1 
ATOM   7135 H H    . LEU B 1 167 ? -32.46426 -5.25991  -42.69174 1.000 59.43473  ? 167 LEU B H    1 
ATOM   7136 H HA   . LEU B 1 167 ? -34.29158 -5.99715  -44.52580 1.000 59.23001  ? 167 LEU B HA   1 
ATOM   7137 H HB2  . LEU B 1 167 ? -31.71199 -7.04490  -44.07483 1.000 57.80380  ? 167 LEU B HB2  1 
ATOM   7138 H HB3  . LEU B 1 167 ? -32.64762 -7.45106  -45.29345 1.000 57.80380  ? 167 LEU B HB3  1 
ATOM   7139 H HG   . LEU B 1 167 ? -31.43574 -4.92840  -44.98002 1.000 55.26008  ? 167 LEU B HG   1 
ATOM   7140 H HD11 . LEU B 1 167 ? -29.97272 -6.69604  -45.66499 1.000 63.58952  ? 167 LEU B HD11 1 
ATOM   7141 H HD12 . LEU B 1 167 ? -30.81309 -6.76980  -47.01104 1.000 63.58952  ? 167 LEU B HD12 1 
ATOM   7142 H HD13 . LEU B 1 167 ? -30.00522 -5.45042  -46.65033 1.000 63.58952  ? 167 LEU B HD13 1 
ATOM   7143 H HD21 . LEU B 1 167 ? -33.31704 -4.44150  -46.07832 1.000 52.65695  ? 167 LEU B HD21 1 
ATOM   7144 H HD22 . LEU B 1 167 ? -32.25606 -4.59859  -47.25013 1.000 52.65695  ? 167 LEU B HD22 1 
ATOM   7145 H HD23 . LEU B 1 167 ? -33.26356 -5.78344  -46.92676 1.000 52.65695  ? 167 LEU B HD23 1 
ATOM   7146 N N    . PRO B 1 168 ? -34.89149 -8.38892  -43.80469 1.000 65.09300  ? 168 PRO B N    1 
ATOM   7147 C CA   . PRO B 1 168 ? -35.56147 -9.49523  -43.10299 1.000 69.07846  ? 168 PRO B CA   1 
ATOM   7148 C C    . PRO B 1 168 ? -34.73336 -10.18630 -42.03042 1.000 66.49467  ? 168 PRO B C    1 
ATOM   7149 O O    . PRO B 1 168 ? -35.24724 -10.48524 -40.94783 1.000 69.95117  ? 168 PRO B O    1 
ATOM   7150 C CB   . PRO B 1 168 ? -35.89181 -10.46460 -44.24611 1.000 61.03200  ? 168 PRO B CB   1 
ATOM   7151 C CG   . PRO B 1 168 ? -36.14370 -9.56220  -45.41888 1.000 63.06815  ? 168 PRO B CG   1 
ATOM   7152 C CD   . PRO B 1 168 ? -35.19764 -8.38782  -45.25000 1.000 63.93657  ? 168 PRO B CD   1 
ATOM   7153 H HA   . PRO B 1 168 ? -36.36618 -9.15331  -42.68297 1.000 82.88793  ? 168 PRO B HA   1 
ATOM   7154 H HB2  . PRO B 1 168 ? -35.14056 -11.05535 -44.41208 1.000 73.23217  ? 168 PRO B HB2  1 
ATOM   7155 H HB3  . PRO B 1 168 ? -36.68072 -10.98469 -44.02692 1.000 73.23217  ? 168 PRO B HB3  1 
ATOM   7156 H HG2  . PRO B 1 168 ? -35.95704 -10.03774 -46.24345 1.000 75.67555  ? 168 PRO B HG2  1 
ATOM   7157 H HG3  . PRO B 1 168 ? -37.06661 -9.26380  -45.40962 1.000 75.67555  ? 168 PRO B HG3  1 
ATOM   7158 H HD2  . PRO B 1 168 ? -34.39075 -8.51884  -45.77217 1.000 76.71765  ? 168 PRO B HD2  1 
ATOM   7159 H HD3  . PRO B 1 168 ? -35.62948 -7.55878  -45.50905 1.000 76.71765  ? 168 PRO B HD3  1 
ATOM   7160 N N    . THR B 1 169 ? -33.46380 -10.44338 -42.30497 1.000 61.89716  ? 169 THR B N    1 
ATOM   7161 C CA   . THR B 1 169 ? -32.64103 -11.19235 -41.35691 1.000 59.29098  ? 169 THR B CA   1 
ATOM   7162 C C    . THR B 1 169 ? -32.24919 -10.38293 -40.11881 1.000 56.85092  ? 169 THR B C    1 
ATOM   7163 O O    . THR B 1 169 ? -31.45706 -10.88537 -39.30838 1.000 63.14642  ? 169 THR B O    1 
ATOM   7164 C CB   . THR B 1 169 ? -31.37499 -11.69057 -42.05298 1.000 73.53633  ? 169 THR B CB   1 
ATOM   7165 O OG1  . THR B 1 169 ? -30.63597 -10.56658 -42.54639 1.000 72.31286  ? 169 THR B OG1  1 
ATOM   7166 C CG2  . THR B 1 169 ? -31.72440 -12.61908 -43.21004 1.000 74.35005  ? 169 THR B CG2  1 
ATOM   7167 H H    . THR B 1 169 ? -33.05780 -10.19970 -43.02288 1.000 74.27036  ? 169 THR B H    1 
ATOM   7168 H HA   . THR B 1 169 ? -33.15333 -11.95915 -41.05613 1.000 71.14295  ? 169 THR B HA   1 
ATOM   7169 H HB   . THR B 1 169 ? -30.83060 -12.18885 -41.42350 1.000 88.23737  ? 169 THR B HB   1 
ATOM   7170 H HG1  . THR B 1 169 ? -29.88320 -10.81664 -42.82283 1.000 86.76920  ? 169 THR B HG1  1 
ATOM   7171 H HG21 . THR B 1 169 ? -30.91818 -12.87624 -43.68415 1.000 89.21383  ? 169 THR B HG21 1 
ATOM   7172 H HG22 . THR B 1 169 ? -32.16053 -13.41784 -42.87437 1.000 89.21383  ? 169 THR B HG22 1 
ATOM   7173 H HG23 . THR B 1 169 ? -32.32265 -12.16949 -43.82718 1.000 89.21383  ? 169 THR B HG23 1 
ATOM   7174 N N    . GLY B 1 170 ? -32.74840 -9.16456  -39.92133 1.000 54.49396  ? 170 GLY B N    1 
ATOM   7175 C CA   . GLY B 1 170 ? -32.32594 -8.34007  -38.81298 1.000 46.79036  ? 170 GLY B CA   1 
ATOM   7176 C C    . GLY B 1 170 ? -31.07998 -7.52335  -39.07016 1.000 41.11961  ? 170 GLY B C    1 
ATOM   7177 O O    . GLY B 1 170 ? -30.70980 -6.70687  -38.21861 1.000 50.85487  ? 170 GLY B O    1 
ATOM   7178 H H    . GLY B 1 170 ? -33.33945 -8.79641  -40.42603 1.000 65.38652  ? 170 GLY B H    1 
ATOM   7179 H HA2  . GLY B 1 170 ? -33.04282 -7.72518  -38.59186 1.000 56.14220  ? 170 GLY B HA2  1 
ATOM   7180 H HA3  . GLY B 1 170 ? -32.15300 -8.91154  -38.04851 1.000 56.14220  ? 170 GLY B HA3  1 
ATOM   7181 N N    . VAL B 1 171 ? -30.41676 -7.71950  -40.20927 1.000 38.96496  ? 171 VAL B N    1 
ATOM   7182 C CA   . VAL B 1 171 ? -29.28150 -6.88891  -40.59601 1.000 40.76194  ? 171 VAL B CA   1 
ATOM   7183 C C    . VAL B 1 171 ? -29.81546 -5.58885  -41.18376 1.000 38.63934  ? 171 VAL B C    1 
ATOM   7184 O O    . VAL B 1 171 ? -31.02544 -5.43635  -41.38866 1.000 38.53499  ? 171 VAL B O    1 
ATOM   7185 C CB   . VAL B 1 171 ? -28.35617 -7.61043  -41.59352 1.000 42.03039  ? 171 VAL B CB   1 
ATOM   7186 C CG1  . VAL B 1 171 ? -27.89272 -8.94557  -41.02204 1.000 45.09122  ? 171 VAL B CG1  1 
ATOM   7187 C CG2  . VAL B 1 171 ? -29.05473 -7.80560  -42.93205 1.000 45.51498  ? 171 VAL B CG2  1 
ATOM   7188 H H    . VAL B 1 171 ? -30.60823 -8.33393  -40.77972 1.000 46.75172  ? 171 VAL B H    1 
ATOM   7189 H HA   . VAL B 1 171 ? -28.75410 -6.68578  -39.80767 1.000 48.90810  ? 171 VAL B HA   1 
ATOM   7190 H HB   . VAL B 1 171 ? -27.57163 -7.06077  -41.74612 1.000 50.43024  ? 171 VAL B HB   1 
ATOM   7191 H HG11 . VAL B 1 171 ? -26.99498 -9.13042  -41.33951 1.000 54.10324  ? 171 VAL B HG11 1 
ATOM   7192 H HG12 . VAL B 1 171 ? -27.89678 -8.89298  -40.05347 1.000 54.10324  ? 171 VAL B HG12 1 
ATOM   7193 H HG13 . VAL B 1 171 ? -28.49840 -9.64306  -41.31797 1.000 54.10324  ? 171 VAL B HG13 1 
ATOM   7194 H HG21 . VAL B 1 171 ? -28.56695 -8.46520  -43.44963 1.000 54.61174  ? 171 VAL B HG21 1 
ATOM   7195 H HG22 . VAL B 1 171 ? -29.96076 -8.11361  -42.77347 1.000 54.61174  ? 171 VAL B HG22 1 
ATOM   7196 H HG23 . VAL B 1 171 ? -29.07121 -6.95944  -43.40601 1.000 54.61174  ? 171 VAL B HG23 1 
ATOM   7197 N N    . HIS B 1 172 ? -28.91783 -4.65364  -41.47905 1.000 39.21698  ? 172 HIS B N    1 
ATOM   7198 C CA   . HIS B 1 172 ? -29.29998 -3.28203  -41.76890 1.000 31.59060  ? 172 HIS B CA   1 
ATOM   7199 C C    . HIS B 1 172 ? -28.60311 -2.77955  -43.02156 1.000 38.12459  ? 172 HIS B C    1 
ATOM   7200 O O    . HIS B 1 172 ? -27.48374 -3.18897  -43.34249 1.000 37.65443  ? 172 HIS B O    1 
ATOM   7201 C CB   . HIS B 1 172 ? -28.97259 -2.38594  -40.57751 1.000 35.29857  ? 172 HIS B CB   1 
ATOM   7202 C CG   . HIS B 1 172 ? -29.62415 -2.83107  -39.30660 1.000 42.07199  ? 172 HIS B CG   1 
ATOM   7203 N ND1  . HIS B 1 172 ? -28.96319 -3.56668  -38.34651 1.000 33.67383  ? 172 HIS B ND1  1 
ATOM   7204 C CD2  . HIS B 1 172 ? -30.88988 -2.67042  -38.85311 1.000 34.99253  ? 172 HIS B CD2  1 
ATOM   7205 C CE1  . HIS B 1 172 ? -29.78974 -3.82635  -37.34910 1.000 35.82411  ? 172 HIS B CE1  1 
ATOM   7206 N NE2  . HIS B 1 172 ? -30.96481 -3.29331  -37.63144 1.000 39.93304  ? 172 HIS B NE2  1 
ATOM   7207 H H    . HIS B 1 172 ? -28.07031 -4.79446  -41.51744 1.000 47.05414  ? 172 HIS B H    1 
ATOM   7208 H HA   . HIS B 1 172 ? -30.25170 -3.23510  -41.95035 1.000 37.90249  ? 172 HIS B HA   1 
ATOM   7209 H HB2  . HIS B 1 172 ? -28.01278 -2.38859  -40.43729 1.000 42.35205  ? 172 HIS B HB2  1 
ATOM   7210 H HB3  . HIS B 1 172 ? -29.27737 -1.48524  -40.76922 1.000 42.35205  ? 172 HIS B HB3  1 
ATOM   7211 H HD2  . HIS B 1 172 ? -31.57930 -2.22224  -39.28755 1.000 41.98481  ? 172 HIS B HD2  1 
ATOM   7212 H HE1  . HIS B 1 172 ? -29.57984 -4.30348  -36.57891 1.000 42.98270  ? 172 HIS B HE1  1 
ATOM   7213 H HE2  . HIS B 1 172 ? -31.66349 -3.33031  -37.13136 1.000 47.91342  ? 172 HIS B HE2  1 
ATOM   7214 N N    . ALA B 1 173 ? -29.28673 -1.87441  -43.72205 1.000 33.32325  ? 173 ALA B N    1 
ATOM   7215 C CA   . ALA B 1 173 ? -28.81965 -1.33097  -44.98665 1.000 32.38317  ? 173 ALA B CA   1 
ATOM   7216 C C    . ALA B 1 173 ? -28.90177 0.18743   -44.96371 1.000 31.68153  ? 173 ALA B C    1 
ATOM   7217 O O    . ALA B 1 173 ? -29.74418 0.77388   -44.27670 1.000 32.30262  ? 173 ALA B O    1 
ATOM   7218 C CB   . ALA B 1 173 ? -29.63976 -1.86458  -46.16662 1.000 31.47790  ? 173 ALA B CB   1 
ATOM   7219 H H    . ALA B 1 173 ? -30.04510 -1.55347  -43.47413 1.000 39.98167  ? 173 ALA B H    1 
ATOM   7220 H HA   . ALA B 1 173 ? -27.89187 -1.58337  -45.11477 1.000 38.85357  ? 173 ALA B HA   1 
ATOM   7221 H HB1  . ALA B 1 173 ? -29.29430 -1.48382  -46.98916 1.000 37.76725  ? 173 ALA B HB1  1 
ATOM   7222 H HB2  . ALA B 1 173 ? -29.56413 -2.83128  -46.19226 1.000 37.76725  ? 173 ALA B HB2  1 
ATOM   7223 H HB3  . ALA B 1 173 ? -30.56775 -1.60843  -46.04772 1.000 37.76725  ? 173 ALA B HB3  1 
ATOM   7224 N N    . GLY B 1 174 ? -28.02161 0.81242   -45.73472 1.000 34.32413  ? 174 GLY B N    1 
ATOM   7225 C CA   . GLY B 1 174 ? -27.97225 2.25733   -45.79184 1.000 32.25497  ? 174 GLY B CA   1 
ATOM   7226 C C    . GLY B 1 174 ? -27.15319 2.72901   -46.97280 1.000 32.57198  ? 174 GLY B C    1 
ATOM   7227 O O    . GLY B 1 174 ? -26.77019 1.94351   -47.84243 1.000 30.13852  ? 174 GLY B O    1 
ATOM   7228 H H    . GLY B 1 174 ? -27.44243 0.41909   -46.23416 1.000 41.18273  ? 174 GLY B H    1 
ATOM   7229 H HA2  . GLY B 1 174 ? -28.87136 2.61141   -45.87619 1.000 38.69973  ? 174 GLY B HA2  1 
ATOM   7230 H HA3  . GLY B 1 174 ? -27.57192 2.60250   -44.97852 1.000 38.69973  ? 174 GLY B HA3  1 
ATOM   7231 N N    . THR B 1 175 ? -26.87733 4.03291   -46.98034 1.000 30.73034  ? 175 THR B N    1 
ATOM   7232 C CA   . THR B 1 175 ? -26.23012 4.71309   -48.09316 1.000 35.34755  ? 175 THR B CA   1 
ATOM   7233 C C    . THR B 1 175 ? -24.94973 5.40023   -47.63555 1.000 31.73852  ? 175 THR B C    1 
ATOM   7234 O O    . THR B 1 175 ? -24.69130 5.56332   -46.44000 1.000 31.47105  ? 175 THR B O    1 
ATOM   7235 C CB   . THR B 1 175 ? -27.14930 5.78047   -48.71348 1.000 32.95327  ? 175 THR B CB   1 
ATOM   7236 O OG1  . THR B 1 175 ? -27.37651 6.82826   -47.75560 1.000 36.79896  ? 175 THR B OG1  1 
ATOM   7237 C CG2  . THR B 1 175 ? -28.47890 5.18610   -49.15270 1.000 27.06779  ? 175 THR B CG2  1 
ATOM   7238 H H    . THR B 1 175 ? -27.06371 4.56017   -46.32700 1.000 36.87018  ? 175 THR B H    1 
ATOM   7239 H HA   . THR B 1 175 ? -26.01225 4.04167   -48.75847 1.000 42.41083  ? 175 THR B HA   1 
ATOM   7240 H HB   . THR B 1 175 ? -26.72258 6.14713   -49.50365 1.000 39.53769  ? 175 THR B HB   1 
ATOM   7241 H HG1  . THR B 1 175 ? -28.02519 7.30360   -47.99822 1.000 44.15252  ? 175 THR B HG1  1 
ATOM   7242 H HG21 . THR B 1 175 ? -28.84788 4.63776   -48.44272 1.000 32.47513  ? 175 THR B HG21 1 
ATOM   7243 H HG22 . THR B 1 175 ? -29.10673 5.89551   -49.36118 1.000 32.47513  ? 175 THR B HG22 1 
ATOM   7244 H HG23 . THR B 1 175 ? -28.35201 4.63614   -49.94159 1.000 32.47513  ? 175 THR B HG23 1 
ATOM   7245 N N    . ASP B 1 176 ? -24.15369 5.82691   -48.61256 1.000 34.96898  ? 176 ASP B N    1 
ATOM   7246 C CA   . ASP B 1 176 ? -23.14375 6.83992   -48.35629 1.000 33.53082  ? 176 ASP B CA   1 
ATOM   7247 C C    . ASP B 1 176 ? -23.83975 8.19512   -48.23291 1.000 32.83804  ? 176 ASP B C    1 
ATOM   7248 O O    . ASP B 1 176 ? -25.06067 8.30926   -48.37854 1.000 35.44482  ? 176 ASP B O    1 
ATOM   7249 C CB   . ASP B 1 176 ? -22.07507 6.82706   -49.44934 1.000 40.80484  ? 176 ASP B CB   1 
ATOM   7250 C CG   . ASP B 1 176 ? -22.62077 7.17507   -50.82817 1.000 39.75323  ? 176 ASP B CG   1 
ATOM   7251 O OD1  . ASP B 1 176 ? -23.67383 7.84446   -50.92579 1.000 35.25613  ? 176 ASP B OD1  1 
ATOM   7252 O OD2  . ASP B 1 176 ? -21.98022 6.77057   -51.82325 1.000 40.59361  ? 176 ASP B OD2  1 
ATOM   7253 H H    . ASP B 1 176 ? -24.18104 5.54555   -49.42477 1.000 41.95654  ? 176 ASP B H    1 
ATOM   7254 H HA   . ASP B 1 176 ? -22.68394 6.64981   -47.52362 1.000 40.23076  ? 176 ASP B HA   1 
ATOM   7255 H HB2  . ASP B 1 176 ? -21.39054 7.47740   -49.22713 1.000 48.95958  ? 176 ASP B HB2  1 
ATOM   7256 H HB3  . ASP B 1 176 ? -21.68629 5.93972   -49.49819 1.000 48.95958  ? 176 ASP B HB3  1 
ATOM   7257 N N    . LEU B 1 177 ? -23.06921 9.24195   -47.95118 1.000 32.70310  ? 177 LEU B N    1 
ATOM   7258 C CA   . LEU B 1 177 ? -23.68405 10.54309  -47.72053 1.000 33.53905  ? 177 LEU B CA   1 
ATOM   7259 C C    . LEU B 1 177 ? -24.07427 11.25920  -49.00749 1.000 40.91898  ? 177 LEU B C    1 
ATOM   7260 O O    . LEU B 1 177 ? -24.72266 12.31027  -48.93081 1.000 38.75953  ? 177 LEU B O    1 
ATOM   7261 C CB   . LEU B 1 177 ? -22.75632 11.42644  -46.88836 1.000 30.84585  ? 177 LEU B CB   1 
ATOM   7262 C CG   . LEU B 1 177 ? -22.95471 11.26796  -45.37639 1.000 33.93040  ? 177 LEU B CG   1 
ATOM   7263 C CD1  . LEU B 1 177 ? -24.25421 11.92374  -44.92591 1.000 32.49169  ? 177 LEU B CD1  1 
ATOM   7264 C CD2  . LEU B 1 177 ? -22.93290 9.78296   -44.96456 1.000 33.47567  ? 177 LEU B CD2  1 
ATOM   7265 H H    . LEU B 1 177 ? -22.21159 9.22408   -47.88981 1.000 39.23749  ? 177 LEU B H    1 
ATOM   7266 H HA   . LEU B 1 177 ? -24.49672 10.41193  -47.20744 1.000 40.24063  ? 177 LEU B HA   1 
ATOM   7267 H HB2  . LEU B 1 177 ? -21.83716 11.19465  -47.09406 1.000 37.00880  ? 177 LEU B HB2  1 
ATOM   7268 H HB3  . LEU B 1 177 ? -22.92305 12.35475  -47.11494 1.000 37.00880  ? 177 LEU B HB3  1 
ATOM   7269 H HG   . LEU B 1 177 ? -22.21965 11.71308  -44.92644 1.000 40.71025  ? 177 LEU B HG   1 
ATOM   7270 H HD11 . LEU B 1 177 ? -24.10738 12.36297  -44.07361 1.000 38.98380  ? 177 LEU B HD11 1 
ATOM   7271 H HD12 . LEU B 1 177 ? -24.52640 12.57509  -45.59115 1.000 38.98380  ? 177 LEU B HD12 1 
ATOM   7272 H HD13 . LEU B 1 177 ? -24.93683 11.24090  -44.83287 1.000 38.98380  ? 177 LEU B HD13 1 
ATOM   7273 H HD21 . LEU B 1 177 ? -23.75836 9.36308   -45.25304 1.000 40.16458  ? 177 LEU B HD21 1 
ATOM   7274 H HD22 . LEU B 1 177 ? -22.17558 9.34899   -45.38770 1.000 40.16458  ? 177 LEU B HD22 1 
ATOM   7275 H HD23 . LEU B 1 177 ? -22.85135 9.72396   -43.99980 1.000 40.16458  ? 177 LEU B HD23 1 
ATOM   7276 N N    . GLU B 1 178 ? -23.70713 10.72938  -50.17575 1.000 38.01698  ? 178 GLU B N    1 
ATOM   7277 C CA   . GLU B 1 178 ? -24.29647 11.16945  -51.43375 1.000 38.03373  ? 178 GLU B CA   1 
ATOM   7278 C C    . GLU B 1 178 ? -25.59963 10.44651  -51.74943 1.000 40.57021  ? 178 GLU B C    1 
ATOM   7279 O O    . GLU B 1 178 ? -26.22240 10.73893  -52.77604 1.000 35.85326  ? 178 GLU B O    1 
ATOM   7280 C CB   . GLU B 1 178 ? -23.32994 10.95771  -52.60166 1.000 39.14492  ? 178 GLU B CB   1 
ATOM   7281 C CG   . GLU B 1 178 ? -22.08701 11.82371  -52.57371 1.000 45.36260  ? 178 GLU B CG   1 
ATOM   7282 C CD   . GLU B 1 178 ? -21.30367 11.76557  -53.87957 1.000 62.46299  ? 178 GLU B CD   1 
ATOM   7283 O OE1  . GLU B 1 178 ? -21.76016 11.09802  -54.83398 1.000 62.48346  ? 178 GLU B OE1  1 
ATOM   7284 O OE2  . GLU B 1 178 ? -20.22634 12.39095  -53.95109 1.000 63.46841  ? 178 GLU B OE2  1 
ATOM   7285 H H    . GLU B 1 178 ? -23.11570 10.11106  -50.26228 1.000 45.61415  ? 178 GLU B H    1 
ATOM   7286 H HA   . GLU B 1 178 ? -24.46848 12.12138  -51.36210 1.000 45.63424  ? 178 GLU B HA   1 
ATOM   7287 H HB2  . GLU B 1 178 ? -23.03913 10.03235  -52.59483 1.000 46.96767  ? 178 GLU B HB2  1 
ATOM   7288 H HB3  . GLU B 1 178 ? -23.80022 11.15158  -53.42759 1.000 46.96767  ? 178 GLU B HB3  1 
ATOM   7289 H HG2  . GLU B 1 178 ? -22.34662 12.74553  -52.41962 1.000 54.42890  ? 178 GLU B HG2  1 
ATOM   7290 H HG3  . GLU B 1 178 ? -21.50483 11.51928  -51.86006 1.000 54.42890  ? 178 GLU B HG3  1 
ATOM   7291 N N    . GLY B 1 179 ? -26.00214 9.48921   -50.91675 1.000 37.57554  ? 179 GLY B N    1 
ATOM   7292 C CA   . GLY B 1 179 ? -27.28174 8.83208   -51.06198 1.000 34.12610  ? 179 GLY B CA   1 
ATOM   7293 C C    . GLY B 1 179 ? -27.29162 7.58228   -51.91027 1.000 31.44675  ? 179 GLY B C    1 
ATOM   7294 O O    . GLY B 1 179 ? -28.37639 7.07575   -52.21287 1.000 35.26372  ? 179 GLY B O    1 
ATOM   7295 H H    . GLY B 1 179 ? -25.53915 9.20292   -50.25096 1.000 45.08442  ? 179 GLY B H    1 
ATOM   7296 H HA2  . GLY B 1 179 ? -27.60197 8.58742   -50.17966 1.000 40.94509  ? 179 GLY B HA2  1 
ATOM   7297 H HA3  . GLY B 1 179 ? -27.90444 9.45962   -51.46116 1.000 40.94509  ? 179 GLY B HA3  1 
ATOM   7298 N N    . ASN B 1 180 ? -26.13240 7.07118   -52.31487 1.000 35.96960  ? 180 ASN B N    1 
ATOM   7299 C CA   . ASN B 1 180 ? -26.06559 5.82104   -53.06083 1.000 31.43223  ? 180 ASN B CA   1 
ATOM   7300 C C    . ASN B 1 180 ? -26.01457 4.65738   -52.07810 1.000 32.61256  ? 180 ASN B C    1 
ATOM   7301 O O    . ASN B 1 180 ? -25.19382 4.65362   -51.15457 1.000 31.81098  ? 180 ASN B O    1 
ATOM   7302 C CB   . ASN B 1 180 ? -24.84218 5.79229   -53.97714 1.000 38.93230  ? 180 ASN B CB   1 
ATOM   7303 C CG   . ASN B 1 180 ? -24.65391 7.08529   -54.74107 1.000 32.46289  ? 180 ASN B CG   1 
ATOM   7304 O OD1  . ASN B 1 180 ? -25.48398 7.45362   -55.56685 1.000 40.18650  ? 180 ASN B OD1  1 
ATOM   7305 N ND2  . ASN B 1 180 ? -23.54843 7.77658   -54.47708 1.000 35.79282  ? 180 ASN B ND2  1 
ATOM   7306 H H    . ASN B 1 180 ? -25.36623 7.43315   -52.16801 1.000 43.15729  ? 180 ASN B H    1 
ATOM   7307 H HA   . ASN B 1 180 ? -26.85469 5.73209   -53.61789 1.000 37.71245  ? 180 ASN B HA   1 
ATOM   7308 H HB2  . ASN B 1 180 ? -24.04832 5.64256   -53.44023 1.000 46.71253  ? 180 ASN B HB2  1 
ATOM   7309 H HB3  . ASN B 1 180 ? -24.94672 5.07520   -54.62193 1.000 46.71253  ? 180 ASN B HB3  1 
ATOM   7310 H HD21 . ASN B 1 180 ? -23.39691 8.51788   -54.88589 1.000 42.94515  ? 180 ASN B HD21 1 
ATOM   7311 H HD22 . ASN B 1 180 ? -22.98528 7.48219   -53.89760 1.000 42.94515  ? 180 ASN B HD22 1 
ATOM   7312 N N    . PHE B 1 181 ? -26.89613 3.67922   -52.26778 1.000 36.85604  ? 181 PHE B N    1 
ATOM   7313 C CA   . PHE B 1 181 ? -26.93523 2.54978   -51.35081 1.000 34.90149  ? 181 PHE B CA   1 
ATOM   7314 C C    . PHE B 1 181 ? -25.63789 1.75472   -51.41036 1.000 30.53829  ? 181 PHE B C    1 
ATOM   7315 O O    . PHE B 1 181 ? -24.97243 1.67599   -52.44715 1.000 32.49913  ? 181 PHE B O    1 
ATOM   7316 C CB   . PHE B 1 181 ? -28.10896 1.61998   -51.67025 1.000 32.29762  ? 181 PHE B CB   1 
ATOM   7317 C CG   . PHE B 1 181 ? -29.30189 1.82546   -50.78195 1.000 38.97307  ? 181 PHE B CG   1 
ATOM   7318 C CD1  . PHE B 1 181 ? -29.41419 1.14690   -49.57788 1.000 37.79058  ? 181 PHE B CD1  1 
ATOM   7319 C CD2  . PHE B 1 181 ? -30.31164 2.69973   -51.14953 1.000 34.94685  ? 181 PHE B CD2  1 
ATOM   7320 C CE1  . PHE B 1 181 ? -30.51392 1.34050   -48.75504 1.000 36.44148  ? 181 PHE B CE1  1 
ATOM   7321 C CE2  . PHE B 1 181 ? -31.41067 2.89687   -50.33425 1.000 37.53709  ? 181 PHE B CE2  1 
ATOM   7322 C CZ   . PHE B 1 181 ? -31.51349 2.21616   -49.13576 1.000 34.51499  ? 181 PHE B CZ   1 
ATOM   7323 H H    . PHE B 1 181 ? -27.47022 3.64789   -52.90734 1.000 44.22102  ? 181 PHE B H    1 
ATOM   7324 H HA   . PHE B 1 181 ? -27.05248 2.89240   -50.45094 1.000 41.87556  ? 181 PHE B HA   1 
ATOM   7325 H HB2  . PHE B 1 181 ? -28.39064 1.77620   -52.58521 1.000 38.75092  ? 181 PHE B HB2  1 
ATOM   7326 H HB3  . PHE B 1 181 ? -27.81649 0.70108   -51.56547 1.000 38.75092  ? 181 PHE B HB3  1 
ATOM   7327 H HD1  . PHE B 1 181 ? -28.74474 0.55545   -49.31917 1.000 45.34247  ? 181 PHE B HD1  1 
ATOM   7328 H HD2  . PHE B 1 181 ? -30.24942 3.16005   -51.95522 1.000 41.92999  ? 181 PHE B HD2  1 
ATOM   7329 H HE1  . PHE B 1 181 ? -30.57868 0.88195   -47.94855 1.000 43.72355  ? 181 PHE B HE1  1 
ATOM   7330 H HE2  . PHE B 1 181 ? -32.08095 3.48766   -50.59232 1.000 45.03828  ? 181 PHE B HE2  1 
ATOM   7331 H HZ   . PHE B 1 181 ? -32.25294 2.34686   -48.58710 1.000 41.41176  ? 181 PHE B HZ   1 
ATOM   7332 N N    . TYR B 1 182 ? -25.27514 1.18110   -50.26641 1.000 35.40155  ? 182 TYR B N    1 
ATOM   7333 C CA   . TYR B 1 182 ? -24.37039 0.04169   -50.23057 1.000 37.56973  ? 182 TYR B CA   1 
ATOM   7334 C C    . TYR B 1 182 ? -25.18653 -1.20613  -50.53801 1.000 33.19890  ? 182 TYR B C    1 
ATOM   7335 O O    . TYR B 1 182 ? -26.19583 -1.46822  -49.87481 1.000 34.97876  ? 182 TYR B O    1 
ATOM   7336 C CB   . TYR B 1 182 ? -23.69486 -0.08580  -48.86806 1.000 34.39170  ? 182 TYR B CB   1 
ATOM   7337 C CG   . TYR B 1 182 ? -22.70756 1.01064   -48.57693 1.000 36.12283  ? 182 TYR B CG   1 
ATOM   7338 C CD1  . TYR B 1 182 ? -21.41370 0.95064   -49.07450 1.000 34.19830  ? 182 TYR B CD1  1 
ATOM   7339 C CD2  . TYR B 1 182 ? -23.06648 2.10751   -47.80407 1.000 33.77326  ? 182 TYR B CD2  1 
ATOM   7340 C CE1  . TYR B 1 182 ? -20.50290 1.95079   -48.81205 1.000 31.68857  ? 182 TYR B CE1  1 
ATOM   7341 C CE2  . TYR B 1 182 ? -22.16502 3.11498   -47.53812 1.000 28.60978  ? 182 TYR B CE2  1 
ATOM   7342 C CZ   . TYR B 1 182 ? -20.88301 3.03288   -48.04397 1.000 34.37613  ? 182 TYR B CZ   1 
ATOM   7343 O OH   . TYR B 1 182 ? -19.97659 4.03530   -47.78230 1.000 31.78837  ? 182 TYR B OH   1 
ATOM   7344 H H    . TYR B 1 182 ? -25.54322 1.43741   -49.49050 1.000 42.47563  ? 182 TYR B H    1 
ATOM   7345 H HA   . TYR B 1 182 ? -23.66836 0.15495   -50.89028 1.000 45.07745  ? 182 TYR B HA   1 
ATOM   7346 H HB2  . TYR B 1 182 ? -24.37654 -0.06132  -48.17841 1.000 41.26381  ? 182 TYR B HB2  1 
ATOM   7347 H HB3  . TYR B 1 182 ? -23.21849 -0.93007  -48.83385 1.000 41.26381  ? 182 TYR B HB3  1 
ATOM   7348 H HD1  . TYR B 1 182 ? -21.15687 0.22317   -49.59386 1.000 41.03173  ? 182 TYR B HD1  1 
ATOM   7349 H HD2  . TYR B 1 182 ? -23.92898 2.16278   -47.46065 1.000 40.52168  ? 182 TYR B HD2  1 
ATOM   7350 H HE1  . TYR B 1 182 ? -19.63816 1.89714   -49.15004 1.000 38.02006  ? 182 TYR B HE1  1 
ATOM   7351 H HE2  . TYR B 1 182 ? -22.41841 3.84545   -47.02130 1.000 34.32551  ? 182 TYR B HE2  1 
ATOM   7352 H HH   . TYR B 1 182 ? -20.38140 4.74409   -47.58393 1.000 38.13982  ? 182 TYR B HH   1 
ATOM   7353 N N    . GLY B 1 183 ? -24.77101 -1.96123  -51.54716 1.000 36.06661  ? 183 GLY B N    1 
ATOM   7354 C CA   . GLY B 1 183 ? -25.46383 -3.17122  -51.91327 1.000 39.14643  ? 183 GLY B CA   1 
ATOM   7355 C C    . GLY B 1 183 ? -26.62046 -2.90339  -52.85423 1.000 48.48581  ? 183 GLY B C    1 
ATOM   7356 O O    . GLY B 1 183 ? -26.84965 -1.77186  -53.29576 1.000 37.26772  ? 183 GLY B O    1 
ATOM   7357 H H    . GLY B 1 183 ? -24.08428 -1.78649  -52.03447 1.000 43.27371  ? 183 GLY B H    1 
ATOM   7358 H HA2  . GLY B 1 183 ? -24.84547 -3.77650  -52.35165 1.000 46.96948  ? 183 GLY B HA2  1 
ATOM   7359 H HA3  . GLY B 1 183 ? -25.81076 -3.59817  -51.11436 1.000 46.96948  ? 183 GLY B HA3  1 
ATOM   7360 N N    . PRO B 1 184 ? -27.38080 -3.95161  -53.17257 1.000 45.44574  ? 184 PRO B N    1 
ATOM   7361 C CA   . PRO B 1 184 ? -28.43505 -3.82788  -54.18526 1.000 48.39352  ? 184 PRO B CA   1 
ATOM   7362 C C    . PRO B 1 184 ? -29.80571 -3.54978  -53.59158 1.000 49.19090  ? 184 PRO B C    1 
ATOM   7363 O O    . PRO B 1 184 ? -30.80305 -4.12358  -54.03917 1.000 48.43730  ? 184 PRO B O    1 
ATOM   7364 C CB   . PRO B 1 184 ? -28.40067 -5.20230  -54.85738 1.000 48.36872  ? 184 PRO B CB   1 
ATOM   7365 C CG   . PRO B 1 184 ? -28.13775 -6.12000  -53.67758 1.000 43.71595  ? 184 PRO B CG   1 
ATOM   7366 C CD   . PRO B 1 184 ? -27.21238 -5.35078  -52.74048 1.000 42.57718  ? 184 PRO B CD   1 
ATOM   7367 H HA   . PRO B 1 184 ? -28.21540 -3.12714  -54.81899 1.000 58.06600  ? 184 PRO B HA   1 
ATOM   7368 H HB2  . PRO B 1 184 ? -29.25097 -5.39795  -55.28118 1.000 58.03624  ? 184 PRO B HB2  1 
ATOM   7369 H HB3  . PRO B 1 184 ? -27.68599 -5.24604  -55.51177 1.000 58.03624  ? 184 PRO B HB3  1 
ATOM   7370 H HG2  . PRO B 1 184 ? -28.97503 -6.33058  -53.23540 1.000 52.45292  ? 184 PRO B HG2  1 
ATOM   7371 H HG3  . PRO B 1 184 ? -27.71182 -6.93476  -53.98686 1.000 52.45292  ? 184 PRO B HG3  1 
ATOM   7372 H HD2  . PRO B 1 184 ? -27.48607 -5.46226  -51.81659 1.000 51.08638  ? 184 PRO B HD2  1 
ATOM   7373 H HD3  . PRO B 1 184 ? -26.29250 -5.63802  -52.85095 1.000 51.08638  ? 184 PRO B HD3  1 
ATOM   7374 N N    . PHE B 1 185 ? -29.87610 -2.68997  -52.58482 1.000 43.96675  ? 185 PHE B N    1 
ATOM   7375 C CA   . PHE B 1 185 ? -31.12270 -2.43685  -51.88030 1.000 40.78491  ? 185 PHE B CA   1 
ATOM   7376 C C    . PHE B 1 185 ? -31.73440 -1.11571  -52.33128 1.000 47.55139  ? 185 PHE B C    1 
ATOM   7377 O O    . PHE B 1 185 ? -31.05479 -0.23760  -52.87174 1.000 37.33405  ? 185 PHE B O    1 
ATOM   7378 C CB   . PHE B 1 185 ? -30.88634 -2.43171  -50.36753 1.000 41.27451  ? 185 PHE B CB   1 
ATOM   7379 C CG   . PHE B 1 185 ? -30.03729 -3.57665  -49.88988 1.000 40.95822  ? 185 PHE B CG   1 
ATOM   7380 C CD1  . PHE B 1 185 ? -30.53322 -4.86915  -49.89717 1.000 42.30378  ? 185 PHE B CD1  1 
ATOM   7381 C CD2  . PHE B 1 185 ? -28.74043 -3.36372  -49.44726 1.000 42.86500  ? 185 PHE B CD2  1 
ATOM   7382 C CE1  . PHE B 1 185 ? -29.75705 -5.92932  -49.47000 1.000 43.37816  ? 185 PHE B CE1  1 
ATOM   7383 C CE2  . PHE B 1 185 ? -27.95547 -4.42337  -49.01317 1.000 41.14319  ? 185 PHE B CE2  1 
ATOM   7384 C CZ   . PHE B 1 185 ? -28.46645 -5.70774  -49.02464 1.000 38.21963  ? 185 PHE B CZ   1 
ATOM   7385 H H    . PHE B 1 185 ? -29.20771 -2.23679  -52.28905 1.000 52.75388  ? 185 PHE B H    1 
ATOM   7386 H HA   . PHE B 1 185 ? -31.76015 -3.13945  -52.08253 1.000 48.93566  ? 185 PHE B HA   1 
ATOM   7387 H HB2  . PHE B 1 185 ? -30.43762 -1.60702  -50.12372 1.000 49.52319  ? 185 PHE B HB2  1 
ATOM   7388 H HB3  . PHE B 1 185 ? -31.74331 -2.48892  -49.91672 1.000 49.52319  ? 185 PHE B HB3  1 
ATOM   7389 H HD1  . PHE B 1 185 ? -31.40065 -5.02592  -50.19363 1.000 50.75830  ? 185 PHE B HD1  1 
ATOM   7390 H HD2  . PHE B 1 185 ? -28.39257 -2.50125  -49.44114 1.000 51.43177  ? 185 PHE B HD2  1 
ATOM   7391 H HE1  . PHE B 1 185 ? -30.10265 -6.79263  -49.48193 1.000 52.04756  ? 185 PHE B HE1  1 
ATOM   7392 H HE2  . PHE B 1 185 ? -27.08797 -4.26947  -48.71539 1.000 49.36559  ? 185 PHE B HE2  1 
ATOM   7393 H HZ   . PHE B 1 185 ? -27.94431 -6.42032  -48.73393 1.000 45.85733  ? 185 PHE B HZ   1 
ATOM   7394 N N    . VAL B 1 186 ? -33.04598 -0.99647  -52.11284 1.000 37.80700  ? 186 VAL B N    1 
ATOM   7395 C CA   . VAL B 1 186 ? -33.80201 0.20776   -52.42865 1.000 42.22116  ? 186 VAL B CA   1 
ATOM   7396 C C    . VAL B 1 186 ? -34.60054 0.62107   -51.20110 1.000 34.93013  ? 186 VAL B C    1 
ATOM   7397 O O    . VAL B 1 186 ? -34.96080 -0.21061  -50.36176 1.000 35.33642  ? 186 VAL B O    1 
ATOM   7398 C CB   . VAL B 1 186 ? -34.74104 0.00144   -53.63990 1.000 45.21408  ? 186 VAL B CB   1 
ATOM   7399 C CG1  . VAL B 1 186 ? -33.93174 -0.29942  -54.88501 1.000 42.68467  ? 186 VAL B CG1  1 
ATOM   7400 C CG2  . VAL B 1 186 ? -35.74596 -1.11635  -53.36323 1.000 40.37210  ? 186 VAL B CG2  1 
ATOM   7401 H H    . VAL B 1 186 ? -33.53020 -1.62035  -51.77238 1.000 45.36217  ? 186 VAL B H    1 
ATOM   7402 H HA   . VAL B 1 186 ? -33.18197 0.92185   -52.64436 1.000 50.65916  ? 186 VAL B HA   1 
ATOM   7403 H HB   . VAL B 1 186 ? -35.24193 0.81812   -53.79170 1.000 54.25067  ? 186 VAL B HB   1 
ATOM   7404 H HG11 . VAL B 1 186 ? -34.39004 0.06931   -55.65630 1.000 51.21537  ? 186 VAL B HG11 1 
ATOM   7405 H HG12 . VAL B 1 186 ? -33.05452 0.10508   -54.79688 1.000 51.21537  ? 186 VAL B HG12 1 
ATOM   7406 H HG13 . VAL B 1 186 ? -33.84462 -1.26078  -54.98038 1.000 51.21537  ? 186 VAL B HG13 1 
ATOM   7407 H HG21 . VAL B 1 186 ? -36.23394 -1.31125  -54.17857 1.000 48.44030  ? 186 VAL B HG21 1 
ATOM   7408 H HG22 . VAL B 1 186 ? -35.26645 -1.90613  -53.06790 1.000 48.44030  ? 186 VAL B HG22 1 
ATOM   7409 H HG23 . VAL B 1 186 ? -36.36042 -0.82456  -52.67171 1.000 48.44030  ? 186 VAL B HG23 1 
ATOM   7410 N N    . ASP B 1 187 ? -34.87875 1.92341   -51.09990 1.000 36.20133  ? 187 ASP B N    1 
ATOM   7411 C CA   . ASP B 1 187 ? -35.65694 2.46218   -49.98322 1.000 34.31537  ? 187 ASP B CA   1 
ATOM   7412 C C    . ASP B 1 187 ? -37.14648 2.30585   -50.30014 1.000 31.65942  ? 187 ASP B C    1 
ATOM   7413 O O    . ASP B 1 187 ? -37.86528 3.25325   -50.62581 1.000 36.33081  ? 187 ASP B O    1 
ATOM   7414 C CB   . ASP B 1 187 ? -35.27547 3.91021   -49.69019 1.000 33.52536  ? 187 ASP B CB   1 
ATOM   7415 C CG   . ASP B 1 187 ? -35.19389 4.77663   -50.93877 1.000 34.27116  ? 187 ASP B CG   1 
ATOM   7416 O OD1  . ASP B 1 187 ? -35.40722 4.26199   -52.05364 1.000 38.77090  ? 187 ASP B OD1  1 
ATOM   7417 O OD2  . ASP B 1 187 ? -34.90796 5.98549   -50.80225 1.000 37.71390  ? 187 ASP B OD2  1 
ATOM   7418 H H    . ASP B 1 187 ? -34.62629 2.51715   -51.66854 1.000 43.43537  ? 187 ASP B H    1 
ATOM   7419 H HA   . ASP B 1 187 ? -35.45868 1.94899   -49.18433 1.000 41.17222  ? 187 ASP B HA   1 
ATOM   7420 H HB2  . ASP B 1 187 ? -35.94262 4.29773   -49.10228 1.000 40.22420  ? 187 ASP B HB2  1 
ATOM   7421 H HB3  . ASP B 1 187 ? -34.40594 3.92494   -49.26055 1.000 40.22420  ? 187 ASP B HB3  1 
ATOM   7422 N N    . ARG B 1 188 ? -37.60119 1.05930   -50.19219 1.000 40.76573  ? 188 ARG B N    1 
ATOM   7423 C CA   . ARG B 1 188 ? -38.98533 0.68468   -50.43839 1.000 35.59968  ? 188 ARG B CA   1 
ATOM   7424 C C    . ARG B 1 188 ? -39.32324 -0.49144  -49.53542 1.000 37.04511  ? 188 ARG B C    1 
ATOM   7425 O O    . ARG B 1 188 ? -38.50182 -1.39417  -49.35587 1.000 39.04823  ? 188 ARG B O    1 
ATOM   7426 C CB   . ARG B 1 188 ? -39.20893 0.31165   -51.90874 1.000 37.65602  ? 188 ARG B CB   1 
ATOM   7427 C CG   . ARG B 1 188 ? -40.56949 -0.30446  -52.19617 1.000 45.72201  ? 188 ARG B CG   1 
ATOM   7428 C CD   . ARG B 1 188 ? -40.79015 -0.52030  -53.68956 1.000 51.28554  ? 188 ARG B CD   1 
ATOM   7429 N NE   . ARG B 1 188 ? -42.13351 -1.01512  -53.97183 1.000 49.77359  ? 188 ARG B NE   1 
ATOM   7430 C CZ   . ARG B 1 188 ? -42.43253 -2.26060  -54.32177 1.000 57.27293  ? 188 ARG B CZ   1 
ATOM   7431 N NH1  . ARG B 1 188 ? -41.49410 -3.17491  -54.50994 1.000 67.76039  ? 188 ARG B NH1  1 
ATOM   7432 N NH2  . ARG B 1 188 ? -43.70826 -2.59651  -54.48792 1.000 68.08528  ? 188 ARG B NH2  1 
ATOM   7433 H H    . ARG B 1 188 ? -37.10789 0.39092   -49.96967 1.000 48.91265  ? 188 ARG B H    1 
ATOM   7434 H HA   . ARG B 1 188 ? -39.57722 1.42285   -50.22467 1.000 42.71339  ? 188 ARG B HA   1 
ATOM   7435 H HB2  . ARG B 1 188 ? -39.12966 1.11424   -52.44769 1.000 45.18099  ? 188 ARG B HB2  1 
ATOM   7436 H HB3  . ARG B 1 188 ? -38.53290 -0.33247  -52.17140 1.000 45.18099  ? 188 ARG B HB3  1 
ATOM   7437 H HG2  . ARG B 1 188 ? -40.63126 -1.16499  -51.75279 1.000 54.86019  ? 188 ARG B HG2  1 
ATOM   7438 H HG3  . ARG B 1 188 ? -41.26457 0.28787   -51.86920 1.000 54.86019  ? 188 ARG B HG3  1 
ATOM   7439 H HD2  . ARG B 1 188 ? -40.67236 0.32221   -54.15562 1.000 61.53642  ? 188 ARG B HD2  1 
ATOM   7440 H HD3  . ARG B 1 188 ? -40.15099 -1.17254  -54.01662 1.000 61.53642  ? 188 ARG B HD3  1 
ATOM   7441 H HE   . ARG B 1 188 ? -42.78329 -0.45556  -53.90634 1.000 59.72208  ? 188 ARG B HE   1 
ATOM   7442 H HH11 . ARG B 1 188 ? -40.66572 -2.96864  -54.40576 1.000 81.30624  ? 188 ARG B HH11 1 
ATOM   7443 H HH12 . ARG B 1 188 ? -41.71275 -3.97524  -54.73637 1.000 81.30624  ? 188 ARG B HH12 1 
ATOM   7444 H HH21 . ARG B 1 188 ? -44.32626 -2.01043  -54.36883 1.000 81.69610  ? 188 ARG B HH21 1 
ATOM   7445 H HH22 . ARG B 1 188 ? -43.91539 -3.39985  -54.71449 1.000 81.69610  ? 188 ARG B HH22 1 
ATOM   7446 N N    . GLN B 1 189 ? -40.53371 -0.48121  -48.97451 1.000 39.73636  ? 189 GLN B N    1 
ATOM   7447 C CA   . GLN B 1 189 ? -40.96825 -1.54745  -48.07212 1.000 42.32614  ? 189 GLN B CA   1 
ATOM   7448 C C    . GLN B 1 189 ? -41.48118 -2.71330  -48.91218 1.000 47.25185  ? 189 GLN B C    1 
ATOM   7449 O O    . GLN B 1 189 ? -42.68299 -2.91034  -49.11356 1.000 39.32796  ? 189 GLN B O    1 
ATOM   7450 C CB   . GLN B 1 189 ? -42.02719 -1.04987  -47.09966 1.000 39.67038  ? 189 GLN B CB   1 
ATOM   7451 C CG   . GLN B 1 189 ? -42.58971 -2.14887  -46.21818 1.000 36.84399  ? 189 GLN B CG   1 
ATOM   7452 C CD   . GLN B 1 189 ? -43.33533 -1.60851  -45.01673 1.000 42.22381  ? 189 GLN B CD   1 
ATOM   7453 O OE1  . GLN B 1 189 ? -42.98079 -0.56283  -44.47346 1.000 40.29857  ? 189 GLN B OE1  1 
ATOM   7454 N NE2  . GLN B 1 189 ? -44.37700 -2.31878  -44.59533 1.000 34.54550  ? 189 GLN B NE2  1 
ATOM   7455 H H    . GLN B 1 189 ? -41.12157 0.13349   -49.10162 1.000 47.67740  ? 189 GLN B H    1 
ATOM   7456 H HA   . GLN B 1 189 ? -40.20452 -1.84828  -47.55528 1.000 50.78514  ? 189 GLN B HA   1 
ATOM   7457 H HB2  . GLN B 1 189 ? -41.63298 -0.37671  -46.52316 1.000 47.59823  ? 189 GLN B HB2  1 
ATOM   7458 H HB3  . GLN B 1 189 ? -42.76148 -0.66600  -47.60400 1.000 47.59823  ? 189 GLN B HB3  1 
ATOM   7459 H HG2  . GLN B 1 189 ? -43.20736 -2.68656  -46.73807 1.000 44.20655  ? 189 GLN B HG2  1 
ATOM   7460 H HG3  . GLN B 1 189 ? -41.85996 -2.70051  -45.89561 1.000 44.20655  ? 189 GLN B HG3  1 
ATOM   7461 H HE21 . GLN B 1 189 ? -44.59539 -3.04448  -45.00186 1.000 41.44837  ? 189 GLN B HE21 1 
ATOM   7462 H HE22 . GLN B 1 189 ? -44.83251 -2.05258  -43.91617 1.000 41.44837  ? 189 GLN B HE22 1 
ATOM   7463 N N    . THR B 1 190 ? -40.53218 -3.49379  -49.41841 1.000 40.05638  ? 190 THR B N    1 
ATOM   7464 C CA   . THR B 1 190 ? -40.82009 -4.71251  -50.15657 1.000 46.10123  ? 190 THR B CA   1 
ATOM   7465 C C    . THR B 1 190 ? -39.74047 -5.72829  -49.81392 1.000 44.75222  ? 190 THR B C    1 
ATOM   7466 O O    . THR B 1 190 ? -38.62422 -5.36190  -49.43836 1.000 47.50187  ? 190 THR B O    1 
ATOM   7467 C CB   . THR B 1 190 ? -40.88814 -4.46021  -51.67615 1.000 44.84949  ? 190 THR B CB   1 
ATOM   7468 O OG1  . THR B 1 190 ? -41.27932 -5.66523  -52.34704 1.000 51.25229  ? 190 THR B OG1  1 
ATOM   7469 C CG2  . THR B 1 190 ? -39.54224 -3.98034  -52.22988 1.000 44.61833  ? 190 THR B CG2  1 
ATOM   7470 H H    . THR B 1 190 ? -39.69080 -3.33204  -49.34418 1.000 48.06143  ? 190 THR B H    1 
ATOM   7471 H HA   . THR B 1 190 ? -41.68004 -5.07849  -49.89686 1.000 55.31525  ? 190 THR B HA   1 
ATOM   7472 H HB   . THR B 1 190 ? -41.54025 -3.76303  -51.84818 1.000 53.81316  ? 190 THR B HB   1 
ATOM   7473 H HG1  . THR B 1 190 ? -40.77412 -6.29702  -52.12074 1.000 61.49652  ? 190 THR B HG1  1 
ATOM   7474 H HG21 . THR B 1 190 ? -39.31604 -4.47915  -53.03046 1.000 53.53577  ? 190 THR B HG21 1 
ATOM   7475 H HG22 . THR B 1 190 ? -39.59148 -3.03697  -52.45015 1.000 53.53577  ? 190 THR B HG22 1 
ATOM   7476 H HG23 . THR B 1 190 ? -38.84508 -4.11325  -51.56867 1.000 53.53577  ? 190 THR B HG23 1 
ATOM   7477 N N    . ALA B 1 191 ? -40.08566 -7.00688  -49.93076 1.000 47.73672  ? 191 ALA B N    1 
ATOM   7478 C CA   . ALA B 1 191 ? -39.15704 -8.06895  -49.56585 1.000 45.95421  ? 191 ALA B CA   1 
ATOM   7479 C C    . ALA B 1 191 ? -37.89073 -7.98620  -50.41051 1.000 55.70580  ? 191 ALA B C    1 
ATOM   7480 O O    . ALA B 1 191 ? -37.94970 -8.04606  -51.64304 1.000 51.55692  ? 191 ALA B O    1 
ATOM   7481 C CB   . ALA B 1 191 ? -39.83079 -9.42735  -49.74106 1.000 49.00976  ? 191 ALA B CB   1 
ATOM   7482 H H    . ALA B 1 191 ? -40.84773 -7.28390  -50.21732 1.000 57.27783  ? 191 ALA B H    1 
ATOM   7483 H HA   . ALA B 1 191 ? -38.90579 -7.96862  -48.63434 1.000 55.13882  ? 191 ALA B HA   1 
ATOM   7484 H HB1  . ALA B 1 191 ? -40.04865 -9.55332  -50.67784 1.000 58.80549  ? 191 ALA B HB1  1 
ATOM   7485 H HB2  . ALA B 1 191 ? -39.22148 -10.12237 -49.44679 1.000 58.80549  ? 191 ALA B HB2  1 
ATOM   7486 H HB3  . ALA B 1 191 ? -40.64042 -9.44949  -49.20729 1.000 58.80549  ? 191 ALA B HB3  1 
ATOM   7487 N N    . GLN B 1 192 ? -36.74479 -7.85063  -49.74340 1.000 55.85389  ? 192 GLN B N    1 
ATOM   7488 C CA   . GLN B 1 192 ? -35.45434 -7.74354  -50.40811 1.000 46.87651  ? 192 GLN B CA   1 
ATOM   7489 C C    . GLN B 1 192 ? -34.48021 -8.73982  -49.79438 1.000 44.77429  ? 192 GLN B C    1 
ATOM   7490 O O    . GLN B 1 192 ? -34.65844 -9.20313  -48.66470 1.000 48.74550  ? 192 GLN B O    1 
ATOM   7491 C CB   . GLN B 1 192 ? -34.88926 -6.31858  -50.31306 1.000 39.83261  ? 192 GLN B CB   1 
ATOM   7492 C CG   . GLN B 1 192 ? -35.74488 -5.27209  -51.01682 1.000 45.14150  ? 192 GLN B CG   1 
ATOM   7493 C CD   . GLN B 1 192 ? -35.18327 -3.87138  -50.89166 1.000 38.57514  ? 192 GLN B CD   1 
ATOM   7494 O OE1  . GLN B 1 192 ? -34.07343 -3.59245  -51.34273 1.000 43.88848  ? 192 GLN B OE1  1 
ATOM   7495 N NE2  . GLN B 1 192 ? -35.94999 -2.97989  -50.27355 1.000 49.59526  ? 192 GLN B NE2  1 
ATOM   7496 H H    . GLN B 1 192 ? -36.69173 -7.81774  -48.88567 1.000 67.01844  ? 192 GLN B H    1 
ATOM   7497 H HA   . GLN B 1 192 ? -35.55504 -7.96479  -51.34715 1.000 56.24559  ? 192 GLN B HA   1 
ATOM   7498 H HB2  . GLN B 1 192 ? -34.82628 -6.06965  -49.37766 1.000 47.79291  ? 192 GLN B HB2  1 
ATOM   7499 H HB3  . GLN B 1 192 ? -34.00894 -6.30423  -50.72017 1.000 47.79291  ? 192 GLN B HB3  1 
ATOM   7500 H HG2  . GLN B 1 192 ? -35.79773 -5.49027  -51.96049 1.000 54.16357  ? 192 GLN B HG2  1 
ATOM   7501 H HG3  . GLN B 1 192 ? -36.63242 -5.27490  -50.62545 1.000 54.16357  ? 192 GLN B HG3  1 
ATOM   7502 H HE21 . GLN B 1 192 ? -36.72035 -3.21220  -49.96994 1.000 59.50808  ? 192 GLN B HE21 1 
ATOM   7503 H HE22 . GLN B 1 192 ? -35.67600 -2.17044  -50.17700 1.000 59.50808  ? 192 GLN B HE22 1 
ATOM   7504 N N    . ALA B 1 193 ? -33.43589 -9.05766  -50.55618 1.000 43.74528  ? 193 ALA B N    1 
ATOM   7505 C CA   . ALA B 1 193 ? -32.49299 -10.11193 -50.20923 1.000 50.47996  ? 193 ALA B CA   1 
ATOM   7506 C C    . ALA B 1 193 ? -31.08016 -9.55174  -50.13302 1.000 52.17460  ? 193 ALA B C    1 
ATOM   7507 O O    . ALA B 1 193 ? -30.62159 -8.87914  -51.06301 1.000 49.81391  ? 193 ALA B O    1 
ATOM   7508 C CB   . ALA B 1 193 ? -32.55486 -11.24800 -51.23562 1.000 53.39883  ? 193 ALA B CB   1 
ATOM   7509 H H    . ALA B 1 193 ? -33.24999 -8.66460  -51.29816 1.000 52.48810  ? 193 ALA B H    1 
ATOM   7510 H HA   . ALA B 1 193 ? -32.71612 -10.46279 -49.33287 1.000 60.56972  ? 193 ALA B HA   1 
ATOM   7511 H HB1  . ALA B 1 193 ? -31.88029 -11.90942 -51.01566 1.000 64.07237  ? 193 ALA B HB1  1 
ATOM   7512 H HB2  . ALA B 1 193 ? -33.43620 -11.65212 -51.20665 1.000 64.07237  ? 193 ALA B HB2  1 
ATOM   7513 H HB3  . ALA B 1 193 ? -32.38636 -10.88488 -52.11917 1.000 64.07237  ? 193 ALA B HB3  1 
ATOM   7514 N N    . ALA B 1 194 ? -30.38952 -9.84273  -49.02690 1.000 50.55751  ? 194 ALA B N    1 
ATOM   7515 C CA   . ALA B 1 194 ? -28.99840 -9.42802  -48.88666 1.000 49.66837  ? 194 ALA B CA   1 
ATOM   7516 C C    . ALA B 1 194 ? -28.05494 -10.36034 -49.63531 1.000 49.34730  ? 194 ALA B C    1 
ATOM   7517 O O    . ALA B 1 194 ? -27.04635 -9.91228  -50.19186 1.000 51.05527  ? 194 ALA B O    1 
ATOM   7518 C CB   . ALA B 1 194 ? -28.60750 -9.37522  -47.41022 1.000 39.82442  ? 194 ALA B CB   1 
ATOM   7519 H H    . ALA B 1 194 ? -30.70238 -10.27457 -48.35220 1.000 60.66278  ? 194 ALA B H    1 
ATOM   7520 H HA   . ALA B 1 194 ? -28.90803 -8.53675  -49.25866 1.000 59.59581  ? 194 ALA B HA   1 
ATOM   7521 H HB1  . ALA B 1 194 ? -29.13789 -8.69451  -46.96726 1.000 47.78308  ? 194 ALA B HB1  1 
ATOM   7522 H HB2  . ALA B 1 194 ? -28.77742 -10.24110 -47.00739 1.000 47.78308  ? 194 ALA B HB2  1 
ATOM   7523 H HB3  . ALA B 1 194 ? -27.66485 -9.15732  -47.34071 1.000 47.78308  ? 194 ALA B HB3  1 
ATOM   7524 N N    . GLY B 1 195 ? -28.35682 -11.65215 -49.65548 1.000 39.85500  ? 195 GLY B N    1 
ATOM   7525 C CA   . GLY B 1 195 ? -27.46096 -12.61486 -50.25869 1.000 57.70748  ? 195 GLY B CA   1 
ATOM   7526 C C    . GLY B 1 195 ? -26.45859 -13.17430 -49.26904 1.000 50.52249  ? 195 GLY B C    1 
ATOM   7527 O O    . GLY B 1 195 ? -26.36372 -12.76306 -48.10874 1.000 46.15807  ? 195 GLY B O    1 
ATOM   7528 H H    . GLY B 1 195 ? -29.07487 -11.99152 -49.32559 1.000 47.81977  ? 195 GLY B H    1 
ATOM   7529 H HA2  . GLY B 1 195 ? -27.97824 -13.35209 -50.61898 1.000 69.24275  ? 195 GLY B HA2  1 
ATOM   7530 H HA3  . GLY B 1 195 ? -26.97230 -12.18943 -50.98059 1.000 69.24275  ? 195 GLY B HA3  1 
ATOM   7531 N N    . THR B 1 196 ? -25.67833 -14.13584 -49.75787 1.000 52.21274  ? 196 THR B N    1 
ATOM   7532 C CA   . THR B 1 196 ? -24.79470 -14.90873 -48.89406 1.000 45.21620  ? 196 THR B CA   1 
ATOM   7533 C C    . THR B 1 196 ? -23.68548 -14.02670 -48.33383 1.000 44.37584  ? 196 THR B C    1 
ATOM   7534 O O    . THR B 1 196 ? -22.90133 -13.44118 -49.08799 1.000 46.18053  ? 196 THR B O    1 
ATOM   7535 C CB   . THR B 1 196 ? -24.19620 -16.08446 -49.66345 1.000 48.39600  ? 196 THR B CB   1 
ATOM   7536 O OG1  . THR B 1 196 ? -25.24749 -16.92443 -50.15526 1.000 54.12671  ? 196 THR B OG1  1 
ATOM   7537 C CG2  . THR B 1 196 ? -23.28143 -16.90261 -48.75686 1.000 49.57049  ? 196 THR B CG2  1 
ATOM   7538 H H    . THR B 1 196 ? -25.64305 -14.35939 -50.58755 1.000 62.64906  ? 196 THR B H    1 
ATOM   7539 H HA   . THR B 1 196 ? -25.31309 -15.25459 -48.15072 1.000 54.25321  ? 196 THR B HA   1 
ATOM   7540 H HB   . THR B 1 196 ? -23.67407 -15.75061 -50.40966 1.000 58.06897  ? 196 THR B HB   1 
ATOM   7541 H HG1  . THR B 1 196 ? -25.65859 -17.27617 -49.51270 1.000 64.94582  ? 196 THR B HG1  1 
ATOM   7542 H HG21 . THR B 1 196 ? -23.10174 -17.76660 -49.15952 1.000 59.47836  ? 196 THR B HG21 1 
ATOM   7543 H HG22 . THR B 1 196 ? -22.44136 -16.43593 -48.62500 1.000 59.47836  ? 196 THR B HG22 1 
ATOM   7544 H HG23 . THR B 1 196 ? -23.70449 -17.03898 -47.89470 1.000 59.47836  ? 196 THR B HG23 1 
ATOM   7545 N N    . ASP B 1 197 ? -23.61704 -13.93956 -47.01104 1.000 37.03787  ? 197 ASP B N    1 
ATOM   7546 C CA   . ASP B 1 197 ? -22.53021 -13.23323 -46.35343 1.000 44.76850  ? 197 ASP B CA   1 
ATOM   7547 C C    . ASP B 1 197 ? -21.30937 -14.13956 -46.23320 1.000 48.40794  ? 197 ASP B C    1 
ATOM   7548 O O    . ASP B 1 197 ? -21.42823 -15.36416 -46.15958 1.000 55.66507  ? 197 ASP B O    1 
ATOM   7549 C CB   . ASP B 1 197 ? -22.96676 -12.76509 -44.96662 1.000 44.91274  ? 197 ASP B CB   1 
ATOM   7550 C CG   . ASP B 1 197 ? -22.07652 -11.66996 -44.41551 1.000 46.99363  ? 197 ASP B CG   1 
ATOM   7551 O OD1  . ASP B 1 197 ? -21.36657 -11.02720 -45.21693 1.000 38.96587  ? 197 ASP B OD1  1 
ATOM   7552 O OD2  . ASP B 1 197 ? -22.08608 -11.45274 -43.18414 1.000 49.36578  ? 197 ASP B OD2  1 
ATOM   7553 H H    . ASP B 1 197 ? -24.19109 -14.28306 -46.47060 1.000 44.43921  ? 197 ASP B H    1 
ATOM   7554 H HA   . ASP B 1 197 ? -22.28284 -12.45239 -46.87305 1.000 53.71597  ? 197 ASP B HA   1 
ATOM   7555 H HB2  . ASP B 1 197 ? -23.87147 -12.41920 -45.01925 1.000 53.88906  ? 197 ASP B HB2  1 
ATOM   7556 H HB3  . ASP B 1 197 ? -22.93389 -13.51625 -44.35378 1.000 53.88906  ? 197 ASP B HB3  1 
ATOM   7557 N N    . THR B 1 198 ? -20.12601 -13.52798 -46.20923 1.000 47.94135  ? 198 THR B N    1 
ATOM   7558 C CA   . THR B 1 198 ? -18.88450 -14.26484 -46.02502 1.000 43.74468  ? 198 THR B CA   1 
ATOM   7559 C C    . THR B 1 198 ? -18.05788 -13.62108 -44.91979 1.000 39.35549  ? 198 THR B C    1 
ATOM   7560 O O    . THR B 1 198 ? -18.30287 -12.48582 -44.50216 1.000 37.04290  ? 198 THR B O    1 
ATOM   7561 C CB   . THR B 1 198 ? -18.05547 -14.34081 -47.32102 1.000 50.26768  ? 198 THR B CB   1 
ATOM   7562 O OG1  . THR B 1 198 ? -17.96096 -13.04447 -47.92573 1.000 51.61970  ? 198 THR B OG1  1 
ATOM   7563 C CG2  . THR B 1 198 ? -18.69118 -15.31997 -48.30489 1.000 58.20744  ? 198 THR B CG2  1 
ATOM   7564 H H    . THR B 1 198 ? -20.01925 -12.67933 -46.29863 1.000 57.52339  ? 198 THR B H    1 
ATOM   7565 H HA   . THR B 1 198 ? -19.10000 -15.17089 -45.75384 1.000 52.48738  ? 198 THR B HA   1 
ATOM   7566 H HB   . THR B 1 198 ? -17.16193 -14.65377 -47.10998 1.000 60.31498  ? 198 THR B HB   1 
ATOM   7567 H HG1  . THR B 1 198 ? -18.63644 -12.90056 -48.40388 1.000 61.93741  ? 198 THR B HG1  1 
ATOM   7568 H HG21 . THR B 1 198 ? -18.71354 -14.93041 -49.19295 1.000 69.84270  ? 198 THR B HG21 1 
ATOM   7569 H HG22 . THR B 1 198 ? -18.17655 -16.14167 -48.33445 1.000 69.84270  ? 198 THR B HG22 1 
ATOM   7570 H HG23 . THR B 1 198 ? -19.59787 -15.52615 -48.02866 1.000 69.84270  ? 198 THR B HG23 1 
ATOM   7571 N N    . THR B 1 199 ? -17.07382 -14.37609 -44.44581 1.000 42.47216  ? 199 THR B N    1 
ATOM   7572 C CA   . THR B 1 199 ? -16.19324 -13.90933 -43.38807 1.000 41.71996  ? 199 THR B CA   1 
ATOM   7573 C C    . THR B 1 199 ? -15.05605 -13.08513 -43.97661 1.000 44.11188  ? 199 THR B C    1 
ATOM   7574 O O    . THR B 1 199 ? -14.51310 -13.41042 -45.03652 1.000 41.10900  ? 199 THR B O    1 
ATOM   7575 C CB   . THR B 1 199 ? -15.64033 -15.09801 -42.60455 1.000 38.74618  ? 199 THR B CB   1 
ATOM   7576 O OG1  . THR B 1 199 ? -16.72749 -15.91359 -42.14835 1.000 36.28028  ? 199 THR B OG1  1 
ATOM   7577 C CG2  . THR B 1 199 ? -14.83944 -14.62515 -41.41122 1.000 35.01820  ? 199 THR B CG2  1 
ATOM   7578 H H    . THR B 1 199 ? -16.89493 -15.16999 -44.72386 1.000 50.96036  ? 199 THR B H    1 
ATOM   7579 H HA   . THR B 1 199 ? -16.68550 -13.34535 -42.77121 1.000 50.05772  ? 199 THR B HA   1 
ATOM   7580 H HB   . THR B 1 199 ? -15.05625 -15.61941 -43.17716 1.000 46.48918  ? 199 THR B HB   1 
ATOM   7581 H HG1  . THR B 1 199 ? -17.17704 -15.49774 -41.57340 1.000 43.53010  ? 199 THR B HG1  1 
ATOM   7582 H HG21 . THR B 1 199 ? -15.19865 -13.78648 -41.08184 1.000 42.01562  ? 199 THR B HG21 1 
ATOM   7583 H HG22 . THR B 1 199 ? -14.88011 -15.28532 -40.70170 1.000 42.01562  ? 199 THR B HG22 1 
ATOM   7584 H HG23 . THR B 1 199 ? -13.91269 -14.49259 -41.66511 1.000 42.01562  ? 199 THR B HG23 1 
ATOM   7585 N N    . ILE B 1 200 ? -14.70787 -12.00239 -43.28632 1.000 38.78349  ? 200 ILE B N    1 
ATOM   7586 C CA   . ILE B 1 200 ? -13.66026 -11.09976 -43.74840 1.000 33.76115  ? 200 ILE B CA   1 
ATOM   7587 C C    . ILE B 1 200 ? -12.32798 -11.68754 -43.30066 1.000 38.30849  ? 200 ILE B C    1 
ATOM   7588 O O    . ILE B 1 200 ? -11.86135 -11.42862 -42.18453 1.000 33.76656  ? 200 ILE B O    1 
ATOM   7589 C CB   . ILE B 1 200 ? -13.87089 -9.67016  -43.21823 1.000 32.50012  ? 200 ILE B CB   1 
ATOM   7590 C CG1  . ILE B 1 200 ? -15.29561 -9.18536  -43.51923 1.000 32.06855  ? 200 ILE B CG1  1 
ATOM   7591 C CG2  . ILE B 1 200 ? -12.86987 -8.71860  -43.85198 1.000 29.98960  ? 200 ILE B CG2  1 
ATOM   7592 C CD1  . ILE B 1 200 ? -15.75780 -8.04505  -42.63375 1.000 37.14723  ? 200 ILE B CD1  1 
ATOM   7593 H H    . ILE B 1 200 ? -15.06719 -11.76771 -42.54106 1.000 46.53396  ? 200 ILE B H    1 
ATOM   7594 H HA   . ILE B 1 200 ? -13.66879 -11.03838 -44.71642 1.000 40.50715  ? 200 ILE B HA   1 
ATOM   7595 H HB   . ILE B 1 200 ? -13.73815 -9.68652  -42.25750 1.000 38.99392  ? 200 ILE B HB   1 
ATOM   7596 H HG12 . ILE B 1 200 ? -15.33208 -8.87857  -44.43871 1.000 38.47604  ? 200 ILE B HG12 1 
ATOM   7597 H HG13 . ILE B 1 200 ? -15.90949 -9.92551  -43.39185 1.000 38.47604  ? 200 ILE B HG13 1 
ATOM   7598 H HG21 . ILE B 1 200 ? -13.03982 -7.82006  -43.52849 1.000 35.98129  ? 200 ILE B HG21 1 
ATOM   7599 H HG22 . ILE B 1 200 ? -11.97288 -8.99440  -43.60650 1.000 35.98129  ? 200 ILE B HG22 1 
ATOM   7600 H HG23 . ILE B 1 200 ? -12.97280 -8.74807  -44.81605 1.000 35.98129  ? 200 ILE B HG23 1 
ATOM   7601 H HD11 . ILE B 1 200 ? -15.00471 -7.46149  -42.45151 1.000 44.57045  ? 200 ILE B HD11 1 
ATOM   7602 H HD12 . ILE B 1 200 ? -16.45526 -7.55142  -43.09285 1.000 44.57045  ? 200 ILE B HD12 1 
ATOM   7603 H HD13 . ILE B 1 200 ? -16.10229 -8.40958  -41.80348 1.000 44.57045  ? 200 ILE B HD13 1 
ATOM   7604 N N    . THR B 1 201 ? -11.71363 -12.48509 -44.17909 1.000 39.05644  ? 201 THR B N    1 
ATOM   7605 C CA   . THR B 1 201 ? -10.55303 -13.28484 -43.79755 1.000 36.03176  ? 201 THR B CA   1 
ATOM   7606 C C    . THR B 1 201 ? -9.41612  -12.41605 -43.27212 1.000 32.30084  ? 201 THR B C    1 
ATOM   7607 O O    . THR B 1 201 ? -8.79990  -12.73337 -42.24750 1.000 32.30764  ? 201 THR B O    1 
ATOM   7608 C CB   . THR B 1 201 ? -10.07848 -14.11129 -44.99495 1.000 35.16265  ? 201 THR B CB   1 
ATOM   7609 O OG1  . THR B 1 201 ? -11.16432 -14.90048 -45.49744 1.000 36.56398  ? 201 THR B OG1  1 
ATOM   7610 C CG2  . THR B 1 201 ? -8.92358  -15.02139 -44.59425 1.000 36.32949  ? 201 THR B CG2  1 
ATOM   7611 H H    . THR B 1 201 ? -11.95003 -12.57976 -45.00052 1.000 46.86150  ? 201 THR B H    1 
ATOM   7612 H HA   . THR B 1 201 ? -10.81820 -13.88853 -43.08610 1.000 43.23188  ? 201 THR B HA   1 
ATOM   7613 H HB   . THR B 1 201 ? -9.76563  -13.51725 -45.69506 1.000 42.18895  ? 201 THR B HB   1 
ATOM   7614 H HG1  . THR B 1 201 ? -11.76902 -14.39992 -45.79639 1.000 43.87055  ? 201 THR B HG1  1 
ATOM   7615 H HG21 . THR B 1 201 ? -8.73860  -15.65511 -45.30494 1.000 43.58916  ? 201 THR B HG21 1 
ATOM   7616 H HG22 . THR B 1 201 ? -8.12712  -14.49318 -44.42829 1.000 43.58916  ? 201 THR B HG22 1 
ATOM   7617 H HG23 . THR B 1 201 ? -9.15080  -15.51023 -43.78783 1.000 43.58916  ? 201 THR B HG23 1 
ATOM   7618 N N    . VAL B 1 202 ? -9.11243  -11.31839 -43.96878 1.000 31.12603  ? 202 VAL B N    1 
ATOM   7619 C CA   . VAL B 1 202 ? -7.97790  -10.49194 -43.56921 1.000 32.78491  ? 202 VAL B CA   1 
ATOM   7620 C C    . VAL B 1 202 ? -8.21426  -9.86500  -42.19827 1.000 34.80302  ? 202 VAL B C    1 
ATOM   7621 O O    . VAL B 1 202 ? -7.25847  -9.58414  -41.46533 1.000 32.35164  ? 202 VAL B O    1 
ATOM   7622 C CB   . VAL B 1 202 ? -7.68364  -9.43153  -44.65313 1.000 35.85202  ? 202 VAL B CB   1 
ATOM   7623 C CG1  . VAL B 1 202 ? -8.87927  -8.49985  -44.86219 1.000 38.66029  ? 202 VAL B CG1  1 
ATOM   7624 C CG2  . VAL B 1 202 ? -6.42372  -8.63968  -44.29874 1.000 33.28901  ? 202 VAL B CG2  1 
ATOM   7625 H H    . VAL B 1 202 ? -9.53894  -11.03803 -44.66094 1.000 37.34501  ? 202 VAL B H    1 
ATOM   7626 H HA   . VAL B 1 202 ? -7.19420  -11.05844 -43.49304 1.000 39.33566  ? 202 VAL B HA   1 
ATOM   7627 H HB   . VAL B 1 202 ? -7.52669  -9.88839  -45.49429 1.000 43.01619  ? 202 VAL B HB   1 
ATOM   7628 H HG11 . VAL B 1 202 ? -9.50350  -8.61780  -44.12917 1.000 46.38612  ? 202 VAL B HG11 1 
ATOM   7629 H HG12 . VAL B 1 202 ? -8.56472  -7.58254  -44.88444 1.000 46.38612  ? 202 VAL B HG12 1 
ATOM   7630 H HG13 . VAL B 1 202 ? -9.30988  -8.72235  -45.70241 1.000 46.38612  ? 202 VAL B HG13 1 
ATOM   7631 H HG21 . VAL B 1 202 ? -6.01686  -8.31132  -45.11577 1.000 39.94059  ? 202 VAL B HG21 1 
ATOM   7632 H HG22 . VAL B 1 202 ? -6.66915  -7.89424  -43.72866 1.000 39.94059  ? 202 VAL B HG22 1 
ATOM   7633 H HG23 . VAL B 1 202 ? -5.80485  -9.22306  -43.83231 1.000 39.94059  ? 202 VAL B HG23 1 
ATOM   7634 N N    . ASN B 1 203 ? -9.47791  -9.65310  -41.81571 1.000 29.99904  ? 203 ASN B N    1 
ATOM   7635 C CA   . ASN B 1 203 ? -9.75969  -9.16831  -40.46641 1.000 32.90189  ? 203 ASN B CA   1 
ATOM   7636 C C    . ASN B 1 203 ? -9.56256  -10.27276 -39.43294 1.000 26.30474  ? 203 ASN B C    1 
ATOM   7637 O O    . ASN B 1 203 ? -9.06384  -10.01747 -38.33123 1.000 26.51782  ? 203 ASN B O    1 
ATOM   7638 C CB   . ASN B 1 203 ? -11.18264 -8.61201  -40.38866 1.000 30.33252  ? 203 ASN B CB   1 
ATOM   7639 C CG   . ASN B 1 203 ? -11.37841 -7.37239  -41.24636 1.000 30.41936  ? 203 ASN B CG   1 
ATOM   7640 O OD1  . ASN B 1 203 ? -10.46305 -6.92583  -41.93577 1.000 32.16137  ? 203 ASN B OD1  1 
ATOM   7641 N ND2  . ASN B 1 203 ? -12.58577 -6.82106  -41.21785 1.000 32.00569  ? 203 ASN B ND2  1 
ATOM   7642 H H    . ASN B 1 203 ? -10.17193 -9.77971  -42.30756 1.000 35.99262  ? 203 ASN B H    1 
ATOM   7643 H HA   . ASN B 1 203 ? -9.14525  -8.44621  -40.26162 1.000 39.47604  ? 203 ASN B HA   1 
ATOM   7644 H HB2  . ASN B 1 203 ? -11.80424 -9.29031  -40.69595 1.000 36.39279  ? 203 ASN B HB2  1 
ATOM   7645 H HB3  . ASN B 1 203 ? -11.37905 -8.37422  -39.46899 1.000 36.39279  ? 203 ASN B HB3  1 
ATOM   7646 H HD21 . ASN B 1 203 ? -12.74854 -6.11789  -41.68546 1.000 38.40060  ? 203 ASN B HD21 1 
ATOM   7647 H HD22 . ASN B 1 203 ? -13.20512 -7.16709  -40.73177 1.000 38.40060  ? 203 ASN B HD22 1 
ATOM   7648 N N    . VAL B 1 204 ? -9.94858  -11.50649 -39.76630 1.000 30.62493  ? 204 VAL B N    1 
ATOM   7649 C CA   . VAL B 1 204 ? -9.74372  -12.61750 -38.84107 1.000 29.51567  ? 204 VAL B CA   1 
ATOM   7650 C C    . VAL B 1 204 ? -8.25789  -12.79777 -38.56059 1.000 31.42243  ? 204 VAL B C    1 
ATOM   7651 O O    . VAL B 1 204 ? -7.84544  -13.01605 -37.41451 1.000 32.45197  ? 204 VAL B O    1 
ATOM   7652 C CB   . VAL B 1 204 ? -10.37331 -13.90627 -39.40390 1.000 31.63863  ? 204 VAL B CB   1 
ATOM   7653 C CG1  . VAL B 1 204 ? -10.10115 -15.07744 -38.48458 1.000 28.82803  ? 204 VAL B CG1  1 
ATOM   7654 C CG2  . VAL B 1 204 ? -11.87645 -13.73309 -39.61762 1.000 29.62795  ? 204 VAL B CG2  1 
ATOM   7655 H H    . VAL B 1 204 ? -10.32462 -11.72171 -40.50918 1.000 36.74369  ? 204 VAL B H    1 
ATOM   7656 H HA   . VAL B 1 204 ? -10.18740 -12.41041 -38.00372 1.000 35.41258  ? 204 VAL B HA   1 
ATOM   7657 H HB   . VAL B 1 204 ? -9.96860  -14.09362 -40.26530 1.000 37.96012  ? 204 VAL B HB   1 
ATOM   7658 H HG11 . VAL B 1 204 ? -10.68440 -15.81295 -38.72899 1.000 34.58741  ? 204 VAL B HG11 1 
ATOM   7659 H HG12 . VAL B 1 204 ? -9.17367  -15.34497 -38.58005 1.000 34.58741  ? 204 VAL B HG12 1 
ATOM   7660 H HG13 . VAL B 1 204 ? -10.27501 -14.80748 -37.56927 1.000 34.58741  ? 204 VAL B HG13 1 
ATOM   7661 H HG21 . VAL B 1 204 ? -12.08684 -12.78624 -39.62870 1.000 35.54732  ? 204 VAL B HG21 1 
ATOM   7662 H HG22 . VAL B 1 204 ? -12.12363 -14.13678 -40.46429 1.000 35.54732  ? 204 VAL B HG22 1 
ATOM   7663 H HG23 . VAL B 1 204 ? -12.35082 -14.16888 -38.89239 1.000 35.54732  ? 204 VAL B HG23 1 
ATOM   7664 N N    . LEU B 1 205 ? -7.42846  -12.70417 -39.60161 1.000 32.51135  ? 205 LEU B N    1 
ATOM   7665 C CA   . LEU B 1 205 ? -5.98758  -12.80090 -39.39764 1.000 33.26303  ? 205 LEU B CA   1 
ATOM   7666 C C    . LEU B 1 205 ? -5.48753  -11.65170 -38.53268 1.000 26.45218  ? 205 LEU B C    1 
ATOM   7667 O O    . LEU B 1 205 ? -4.59678  -11.83533 -37.69519 1.000 30.08565  ? 205 LEU B O    1 
ATOM   7668 C CB   . LEU B 1 205 ? -5.26703  -12.82112 -40.74627 1.000 27.42322  ? 205 LEU B CB   1 
ATOM   7669 C CG   . LEU B 1 205 ? -5.63706  -13.98585 -41.66775 1.000 40.19291  ? 205 LEU B CG   1 
ATOM   7670 C CD1  . LEU B 1 205 ? -5.22282  -13.67308 -43.09667 1.000 37.08593  ? 205 LEU B CD1  1 
ATOM   7671 C CD2  . LEU B 1 205 ? -4.99663  -15.28689 -41.19766 1.000 37.10951  ? 205 LEU B CD2  1 
ATOM   7672 H H    . LEU B 1 205 ? -7.67101  -12.58706 -40.41835 1.000 39.00739  ? 205 LEU B H    1 
ATOM   7673 H HA   . LEU B 1 205 ? -5.78407  -13.63308 -38.94271 1.000 39.90940  ? 205 LEU B HA   1 
ATOM   7674 H HB2  . LEU B 1 205 ? -5.47808  -11.99990 -41.21739 1.000 32.90164  ? 205 LEU B HB2  1 
ATOM   7675 H HB3  . LEU B 1 205 ? -4.31254  -12.87321 -40.58158 1.000 32.90164  ? 205 LEU B HB3  1 
ATOM   7676 H HG   . LEU B 1 205 ? -6.59877  -14.11006 -41.64379 1.000 48.22527  ? 205 LEU B HG   1 
ATOM   7677 H HD11 . LEU B 1 205 ? -5.78638  -12.96238 -43.44047 1.000 44.49689  ? 205 LEU B HD11 1 
ATOM   7678 H HD12 . LEU B 1 205 ? -4.29472  -13.39113 -43.10189 1.000 44.49689  ? 205 LEU B HD12 1 
ATOM   7679 H HD13 . LEU B 1 205 ? -5.32922  -14.47084 -43.63812 1.000 44.49689  ? 205 LEU B HD13 1 
ATOM   7680 H HD21 . LEU B 1 205 ? -5.16581  -15.39739 -40.24894 1.000 44.52519  ? 205 LEU B HD21 1 
ATOM   7681 H HD22 . LEU B 1 205 ? -5.38475  -16.02628 -41.69119 1.000 44.52519  ? 205 LEU B HD22 1 
ATOM   7682 H HD23 . LEU B 1 205 ? -4.04133  -15.24557 -41.36069 1.000 44.52519  ? 205 LEU B HD23 1 
ATOM   7683 N N    . ALA B 1 206 ? -6.05469  -10.45711 -38.71820 1.000 29.87973  ? 206 ALA B N    1 
ATOM   7684 C CA   . ALA B 1 206 ? -5.68245  -9.32331  -37.87875 1.000 34.29363  ? 206 ALA B CA   1 
ATOM   7685 C C    . ALA B 1 206 ? -6.05180  -9.57949  -36.42186 1.000 33.74105  ? 206 ALA B C    1 
ATOM   7686 O O    . ALA B 1 206 ? -5.27573  -9.26801  -35.50974 1.000 31.47385  ? 206 ALA B O    1 
ATOM   7687 C CB   . ALA B 1 206 ? -6.35771  -8.05289  -38.39419 1.000 30.79710  ? 206 ALA B CB   1 
ATOM   7688 H H    . ALA B 1 206 ? -6.64862  -10.28117 -39.31477 1.000 35.84945  ? 206 ALA B H    1 
ATOM   7689 H HA   . ALA B 1 206 ? -4.72253  -9.19216  -37.92616 1.000 41.14613  ? 206 ALA B HA   1 
ATOM   7690 H HB1  . ALA B 1 206 ? -5.96898  -7.28492  -37.94696 1.000 36.95029  ? 206 ALA B HB1  1 
ATOM   7691 H HB2  . ALA B 1 206 ? -6.21510  -7.98550  -39.35128 1.000 36.95029  ? 206 ALA B HB2  1 
ATOM   7692 H HB3  . ALA B 1 206 ? -7.30765  -8.10068  -38.20386 1.000 36.95029  ? 206 ALA B HB3  1 
ATOM   7693 N N    . TRP B 1 207 ? -7.22944  -10.16386 -36.18800 1.000 29.31184  ? 207 TRP B N    1 
ATOM   7694 C CA   . TRP B 1 207 ? -7.65270  -10.49715 -34.83030 1.000 30.38879  ? 207 TRP B CA   1 
ATOM   7695 C C    . TRP B 1 207 ? -6.72891  -11.53502 -34.20069 1.000 31.94137  ? 207 TRP B C    1 
ATOM   7696 O O    . TRP B 1 207 ? -6.40008  -11.44751 -33.01114 1.000 32.87449  ? 207 TRP B O    1 
ATOM   7697 C CB   . TRP B 1 207 ? -9.09886  -10.99599 -34.86997 1.000 33.94497  ? 207 TRP B CB   1 
ATOM   7698 C CG   . TRP B 1 207 ? -9.69273  -11.37968 -33.55126 1.000 37.01924  ? 207 TRP B CG   1 
ATOM   7699 C CD1  . TRP B 1 207 ? -10.01003 -10.54688 -32.51682 1.000 32.95104  ? 207 TRP B CD1  1 
ATOM   7700 C CD2  . TRP B 1 207 ? -10.07333 -12.69644 -33.13750 1.000 34.73538  ? 207 TRP B CD2  1 
ATOM   7701 N NE1  . TRP B 1 207 ? -10.55650 -11.26683 -31.48170 1.000 34.04696  ? 207 TRP B NE1  1 
ATOM   7702 C CE2  . TRP B 1 207 ? -10.60373 -12.58899 -31.83774 1.000 32.05489  ? 207 TRP B CE2  1 
ATOM   7703 C CE3  . TRP B 1 207 ? -10.01352 -13.95669 -33.73927 1.000 41.12156  ? 207 TRP B CE3  1 
ATOM   7704 C CZ2  . TRP B 1 207 ? -11.07025 -13.69175 -31.13086 1.000 38.20597  ? 207 TRP B CZ2  1 
ATOM   7705 C CZ3  . TRP B 1 207 ? -10.47458 -15.05132 -33.03278 1.000 37.39292  ? 207 TRP B CZ3  1 
ATOM   7706 C CH2  . TRP B 1 207 ? -10.99941 -14.91111 -31.74587 1.000 37.35973  ? 207 TRP B CH2  1 
ATOM   7707 H H    . TRP B 1 207 ? -7.79895  -10.37666 -36.79626 1.000 35.16798  ? 207 TRP B H    1 
ATOM   7708 H HA   . TRP B 1 207 ? -7.61617  -9.70485  -34.27188 1.000 36.46032  ? 207 TRP B HA   1 
ATOM   7709 H HB2  . TRP B 1 207 ? -9.65325  -10.29147 -35.24037 1.000 40.72773  ? 207 TRP B HB2  1 
ATOM   7710 H HB3  . TRP B 1 207 ? -9.13425  -11.78018 -35.43979 1.000 40.72773  ? 207 TRP B HB3  1 
ATOM   7711 H HD1  . TRP B 1 207 ? -9.87588  -9.62661  -32.51329 1.000 39.53502  ? 207 TRP B HD1  1 
ATOM   7712 H HE1  . TRP B 1 207 ? -10.82503 -10.94067 -30.73263 1.000 40.85013  ? 207 TRP B HE1  1 
ATOM   7713 H HE3  . TRP B 1 207 ? -9.67035  -14.05654 -34.59786 1.000 49.33965  ? 207 TRP B HE3  1 
ATOM   7714 H HZ2  . TRP B 1 207 ? -11.41723 -13.60344 -30.27254 1.000 45.84094  ? 207 TRP B HZ2  1 
ATOM   7715 H HZ3  . TRP B 1 207 ? -10.43474 -15.89561 -33.42072 1.000 44.86527  ? 207 TRP B HZ3  1 
ATOM   7716 H HH2  . TRP B 1 207 ? -11.30793 -15.66477 -31.29675 1.000 44.82545  ? 207 TRP B HH2  1 
ATOM   7717 N N    . LEU B 1 208 ? -6.29929  -12.52754 -34.98210 1.000 33.55912  ? 208 LEU B N    1 
ATOM   7718 C CA   . LEU B 1 208 ? -5.36946  -13.52530 -34.46150 1.000 34.27763  ? 208 LEU B CA   1 
ATOM   7719 C C    . LEU B 1 208 ? -4.03812  -12.89268 -34.07824 1.000 37.88449  ? 208 LEU B C    1 
ATOM   7720 O O    . LEU B 1 208 ? -3.40662  -13.30337 -33.09716 1.000 37.78074  ? 208 LEU B O    1 
ATOM   7721 C CB   . LEU B 1 208 ? -5.15885  -14.63050 -35.49347 1.000 32.47262  ? 208 LEU B CB   1 
ATOM   7722 C CG   . LEU B 1 208 ? -6.41531  -15.44519 -35.79958 1.000 31.91136  ? 208 LEU B CG   1 
ATOM   7723 C CD1  . LEU B 1 208 ? -6.18886  -16.34282 -36.99922 1.000 38.20120  ? 208 LEU B CD1  1 
ATOM   7724 C CD2  . LEU B 1 208 ? -6.84693  -16.25432 -34.57844 1.000 32.28713  ? 208 LEU B CD2  1 
ATOM   7725 H H    . LEU B 1 208 ? -6.52762  -12.64306 -35.80315 1.000 40.26472  ? 208 LEU B H    1 
ATOM   7726 H HA   . LEU B 1 208 ? -5.75268  -13.92439 -33.66477 1.000 41.12693  ? 208 LEU B HA   1 
ATOM   7727 H HB2  . LEU B 1 208 ? -4.85901  -14.22693 -36.32300 1.000 38.96092  ? 208 LEU B HB2  1 
ATOM   7728 H HB3  . LEU B 1 208 ? -4.48425  -15.24215 -35.15926 1.000 38.96092  ? 208 LEU B HB3  1 
ATOM   7729 H HG   . LEU B 1 208 ? -7.13993  -14.83851 -36.01810 1.000 38.28741  ? 208 LEU B HG   1 
ATOM   7730 H HD11 . LEU B 1 208 ? -7.02880  -16.76251 -37.24264 1.000 45.83521  ? 208 LEU B HD11 1 
ATOM   7731 H HD12 . LEU B 1 208 ? -5.86097  -15.80620 -37.73775 1.000 45.83521  ? 208 LEU B HD12 1 
ATOM   7732 H HD13 . LEU B 1 208 ? -5.53522  -17.02097 -36.76732 1.000 45.83521  ? 208 LEU B HD13 1 
ATOM   7733 H HD21 . LEU B 1 208 ? -7.13405  -17.13440 -34.86812 1.000 38.73832  ? 208 LEU B HD21 1 
ATOM   7734 H HD22 . LEU B 1 208 ? -6.09489  -16.33499 -33.97113 1.000 38.73832  ? 208 LEU B HD22 1 
ATOM   7735 H HD23 . LEU B 1 208 ? -7.57963  -15.79552 -34.13849 1.000 38.73832  ? 208 LEU B HD23 1 
ATOM   7736 N N    . TYR B 1 209 ? -3.58592  -11.89980 -34.84669 1.000 33.17625  ? 209 TYR B N    1 
ATOM   7737 C CA   . TYR B 1 209 ? -2.38405  -11.17146 -34.45652 1.000 34.19227  ? 209 TYR B CA   1 
ATOM   7738 C C    . TYR B 1 209 ? -2.60679  -10.41266 -33.15380 1.000 35.29318  ? 209 TYR B C    1 
ATOM   7739 O O    . TYR B 1 209 ? -1.71472  -10.35599 -32.29935 1.000 34.28573  ? 209 TYR B O    1 
ATOM   7740 C CB   . TYR B 1 209 ? -1.96061  -10.21118 -35.56683 1.000 37.37102  ? 209 TYR B CB   1 
ATOM   7741 C CG   . TYR B 1 209 ? -1.12445  -10.84241 -36.65746 1.000 37.34181  ? 209 TYR B CG   1 
ATOM   7742 C CD1  . TYR B 1 209 ? 0.16810   -11.28056 -36.40129 1.000 41.09611  ? 209 TYR B CD1  1 
ATOM   7743 C CD2  . TYR B 1 209 ? -1.61777  -10.98014 -37.94786 1.000 42.70761  ? 209 TYR B CD2  1 
ATOM   7744 C CE1  . TYR B 1 209 ? 0.94157   -11.84919 -37.39469 1.000 37.66886  ? 209 TYR B CE1  1 
ATOM   7745 C CE2  . TYR B 1 209 ? -0.84896  -11.54757 -38.95088 1.000 46.11043  ? 209 TYR B CE2  1 
ATOM   7746 C CZ   . TYR B 1 209 ? 0.43020   -11.98187 -38.66711 1.000 43.43479  ? 209 TYR B CZ   1 
ATOM   7747 O OH   . TYR B 1 209 ? 1.20296   -12.54879 -39.65703 1.000 38.63347  ? 209 TYR B OH   1 
ATOM   7748 H H    . TYR B 1 209 ? -3.94882  -11.63598 -35.58038 1.000 39.80527  ? 209 TYR B H    1 
ATOM   7749 H HA   . TYR B 1 209 ? -1.66368  -11.80711 -34.32263 1.000 41.02449  ? 209 TYR B HA   1 
ATOM   7750 H HB2  . TYR B 1 209 ? -2.75848  -9.84844  -35.98244 1.000 44.83899  ? 209 TYR B HB2  1 
ATOM   7751 H HB3  . TYR B 1 209 ? -1.43695  -9.49572  -35.17339 1.000 44.83899  ? 209 TYR B HB3  1 
ATOM   7752 H HD1  . TYR B 1 209 ? 0.51957   -11.18952 -35.54509 1.000 49.30910  ? 209 TYR B HD1  1 
ATOM   7753 H HD2  . TYR B 1 209 ? -2.47859  -10.68661 -38.14211 1.000 51.24291  ? 209 TYR B HD2  1 
ATOM   7754 H HE1  . TYR B 1 209 ? 1.80397   -12.14125 -37.20530 1.000 45.19640  ? 209 TYR B HE1  1 
ATOM   7755 H HE2  . TYR B 1 209 ? -1.19271  -11.63540 -39.81054 1.000 55.32628  ? 209 TYR B HE2  1 
ATOM   7756 H HH   . TYR B 1 209 ? 1.97466   -12.70564 -39.36468 1.000 46.35394  ? 209 TYR B HH   1 
ATOM   7757 N N    . ALA B 1 210 ? -3.78901  -9.81316  -32.98607 1.000 42.93592  ? 210 ALA B N    1 
ATOM   7758 C CA   . ALA B 1 210 ? -4.10977  -9.17826  -31.71197 1.000 33.96585  ? 210 ALA B CA   1 
ATOM   7759 C C    . ALA B 1 210 ? -4.03684  -10.18794 -30.57467 1.000 36.42754  ? 210 ALA B C    1 
ATOM   7760 O O    . ALA B 1 210 ? -3.57163  -9.86485  -29.47584 1.000 37.83324  ? 210 ALA B O    1 
ATOM   7761 C CB   . ALA B 1 210 ? -5.49586  -8.53523  -31.77101 1.000 32.53432  ? 210 ALA B CB   1 
ATOM   7762 H H    . ALA B 1 210 ? -4.40718  -9.76237  -33.58179 1.000 51.51687  ? 210 ALA B H    1 
ATOM   7763 H HA   . ALA B 1 210 ? -3.46591  -8.47333  -31.54048 1.000 40.75279  ? 210 ALA B HA   1 
ATOM   7764 H HB1  . ALA B 1 210 ? -5.51415  -7.89017  -32.49521 1.000 39.03496  ? 210 ALA B HB1  1 
ATOM   7765 H HB2  . ALA B 1 210 ? -6.15828  -9.22645  -31.92691 1.000 39.03496  ? 210 ALA B HB2  1 
ATOM   7766 H HB3  . ALA B 1 210 ? -5.67393  -8.09065  -30.92748 1.000 39.03496  ? 210 ALA B HB3  1 
ATOM   7767 N N    . ALA B 1 211 ? -4.47581  -11.42411 -30.82771 1.000 38.14195  ? 211 ALA B N    1 
ATOM   7768 C CA   . ALA B 1 211 ? -4.41614  -12.46114 -29.80253 1.000 32.98910  ? 211 ALA B CA   1 
ATOM   7769 C C    . ALA B 1 211 ? -2.97495  -12.75937 -29.41190 1.000 40.54087  ? 211 ALA B C    1 
ATOM   7770 O O    . ALA B 1 211 ? -2.63188  -12.78886 -28.22383 1.000 34.90623  ? 211 ALA B O    1 
ATOM   7771 C CB   . ALA B 1 211 ? -5.10671  -13.73037 -30.30310 1.000 39.21410  ? 211 ALA B CB   1 
ATOM   7772 H H    . ALA B 1 211 ? -4.80863  -11.68315 -31.57719 1.000 45.76412  ? 211 ALA B H    1 
ATOM   7773 H HA   . ALA B 1 211 ? -4.88729  -12.14917 -29.01412 1.000 39.58069  ? 211 ALA B HA   1 
ATOM   7774 H HB1  . ALA B 1 211 ? -4.59472  -14.09878 -31.04002 1.000 47.05069  ? 211 ALA B HB1  1 
ATOM   7775 H HB2  . ALA B 1 211 ? -5.15136  -14.37268 -29.57761 1.000 47.05069  ? 211 ALA B HB2  1 
ATOM   7776 H HB3  . ALA B 1 211 ? -6.00188  -13.50599 -30.60180 1.000 47.05069  ? 211 ALA B HB3  1 
ATOM   7777 N N    . VAL B 1 212 ? -2.11545  -12.98765 -30.40756 1.000 40.52748  ? 212 VAL B N    1 
ATOM   7778 C CA   . VAL B 1 212 ? -0.71343  -13.28864 -30.13354 1.000 40.10860  ? 212 VAL B CA   1 
ATOM   7779 C C    . VAL B 1 212 ? -0.06065  -12.14224 -29.37456 1.000 36.24003  ? 212 VAL B C    1 
ATOM   7780 O O    . VAL B 1 212 ? 0.75433   -12.35884 -28.46891 1.000 37.53432  ? 212 VAL B O    1 
ATOM   7781 C CB   . VAL B 1 212 ? 0.02832   -13.58825 -31.44967 1.000 36.14248  ? 212 VAL B CB   1 
ATOM   7782 C CG1  . VAL B 1 212 ? 1.53271   -13.64301 -31.21540 1.000 35.30334  ? 212 VAL B CG1  1 
ATOM   7783 C CG2  . VAL B 1 212 ? -0.47312  -14.88839 -32.05053 1.000 37.22347  ? 212 VAL B CG2  1 
ATOM   7784 H H    . VAL B 1 212 ? -2.31848  -12.97400 -31.24314 1.000 48.62675  ? 212 VAL B H    1 
ATOM   7785 H HA   . VAL B 1 212 ? -0.67024  -14.07917 -29.57310 1.000 48.12410  ? 212 VAL B HA   1 
ATOM   7786 H HB   . VAL B 1 212 ? -0.14793  -12.87471 -32.08266 1.000 43.36475  ? 212 VAL B HB   1 
ATOM   7787 H HG11 . VAL B 1 212 ? 1.95354   -14.08735 -31.96797 1.000 42.35778  ? 212 VAL B HG11 1 
ATOM   7788 H HG12 . VAL B 1 212 ? 1.87265   -12.73826 -31.13316 1.000 42.35778  ? 212 VAL B HG12 1 
ATOM   7789 H HG13 . VAL B 1 212 ? 1.70745   -14.13748 -30.39939 1.000 42.35778  ? 212 VAL B HG13 1 
ATOM   7790 H HG21 . VAL B 1 212 ? -0.30719  -14.87932 -33.00619 1.000 44.66193  ? 212 VAL B HG21 1 
ATOM   7791 H HG22 . VAL B 1 212 ? -0.00043  -15.62915 -31.63975 1.000 44.66193  ? 212 VAL B HG22 1 
ATOM   7792 H HG23 . VAL B 1 212 ? -1.42479  -14.96840 -31.88078 1.000 44.66193  ? 212 VAL B HG23 1 
ATOM   7793 N N    . ILE B 1 213 ? -0.40149  -10.90394 -29.73599 1.000 33.99731  ? 213 ILE B N    1 
ATOM   7794 C CA   . ILE B 1 213 ? 0.17678   -9.74743  -29.06168 1.000 36.04851  ? 213 ILE B CA   1 
ATOM   7795 C C    . ILE B 1 213 ? -0.25271  -9.70465  -27.60486 1.000 39.59888  ? 213 ILE B C    1 
ATOM   7796 O O    . ILE B 1 213 ? 0.46722   -9.17022  -26.75240 1.000 34.92448  ? 213 ILE B O    1 
ATOM   7797 C CB   . ILE B 1 213 ? -0.21936  -8.45246  -29.79795 1.000 37.32005  ? 213 ILE B CB   1 
ATOM   7798 C CG1  . ILE B 1 213 ? 0.46898   -8.38962  -31.16253 1.000 37.15986  ? 213 ILE B CG1  1 
ATOM   7799 C CG2  . ILE B 1 213 ? 0.11761   -7.23284  -28.94640 1.000 32.72466  ? 213 ILE B CG2  1 
ATOM   7800 C CD1  . ILE B 1 213 ? -0.03456  -7.26390  -32.05161 1.000 43.15443  ? 213 ILE B CD1  1 
ATOM   7801 H H    . ILE B 1 213 ? -0.95902  -10.71045 -30.36155 1.000 40.79055  ? 213 ILE B H    1 
ATOM   7802 H HA   . ILE B 1 213 ? 1.14310   -9.82790  -29.08728 1.000 43.25198  ? 213 ILE B HA   1 
ATOM   7803 H HB   . ILE B 1 213 ? -1.17797  -8.45620  -29.94617 1.000 44.77783  ? 213 ILE B HB   1 
ATOM   7804 H HG12 . ILE B 1 213 ? 1.42005   -8.25626  -31.02619 1.000 44.58560  ? 213 ILE B HG12 1 
ATOM   7805 H HG13 . ILE B 1 213 ? 0.31473   -9.22631  -31.62842 1.000 44.58560  ? 213 ILE B HG13 1 
ATOM   7806 H HG21 . ILE B 1 213 ? 0.13696   -6.44672  -29.51433 1.000 39.26336  ? 213 ILE B HG21 1 
ATOM   7807 H HG22 . ILE B 1 213 ? -0.56082  -7.12907  -28.26093 1.000 39.26336  ? 213 ILE B HG22 1 
ATOM   7808 H HG23 . ILE B 1 213 ? 0.98601   -7.36512  -28.53496 1.000 39.26336  ? 213 ILE B HG23 1 
ATOM   7809 H HD11 . ILE B 1 213 ? 0.37207   -6.43057  -31.76680 1.000 51.77908  ? 213 ILE B HD11 1 
ATOM   7810 H HD12 . ILE B 1 213 ? 0.20991   -7.45405  -32.97084 1.000 51.77908  ? 213 ILE B HD12 1 
ATOM   7811 H HD13 . ILE B 1 213 ? -0.99947  -7.20556  -31.97126 1.000 51.77908  ? 213 ILE B HD13 1 
ATOM   7812 N N    . ASN B 1 214 ? -1.42594  -10.25781 -27.29384 1.000 40.48301  ? 214 ASN B N    1 
ATOM   7813 C CA   . ASN B 1 214 ? -1.97224  -10.25187 -25.94477 1.000 40.26421  ? 214 ASN B CA   1 
ATOM   7814 C C    . ASN B 1 214 ? -1.71789  -11.55932 -25.20118 1.000 33.68110  ? 214 ASN B C    1 
ATOM   7815 O O    . ASN B 1 214 ? -2.36249  -11.81789 -24.17992 1.000 45.96680  ? 214 ASN B O    1 
ATOM   7816 C CB   . ASN B 1 214 ? -3.47173  -9.95128  -25.98933 1.000 41.44751  ? 214 ASN B CB   1 
ATOM   7817 C CG   . ASN B 1 214 ? -3.76324  -8.46897  -26.14769 1.000 47.33640  ? 214 ASN B CG   1 
ATOM   7818 O OD1  . ASN B 1 214 ? -3.94134  -7.75063  -25.16194 1.000 51.27722  ? 214 ASN B OD1  1 
ATOM   7819 N ND2  . ASN B 1 214 ? -3.80515  -8.00228  -27.39057 1.000 40.32844  ? 214 ASN B ND2  1 
ATOM   7820 H H    . ASN B 1 214 ? -1.93387  -10.65178 -27.86516 1.000 48.57338  ? 214 ASN B H    1 
ATOM   7821 H HA   . ASN B 1 214 ? -1.53722  -9.54436  -25.44369 1.000 48.31083  ? 214 ASN B HA   1 
ATOM   7822 H HB2  . ASN B 1 214 ? -3.86635  -10.41779 -26.74268 1.000 49.73078  ? 214 ASN B HB2  1 
ATOM   7823 H HB3  . ASN B 1 214 ? -3.88000  -10.25164 -25.16230 1.000 49.73078  ? 214 ASN B HB3  1 
ATOM   7824 H HD21 . ASN B 1 214 ? -3.96674  -7.16951  -27.53196 1.000 48.38790  ? 214 ASN B HD21 1 
ATOM   7825 H HD22 . ASN B 1 214 ? -3.67070  -8.53288  -28.05388 1.000 48.38790  ? 214 ASN B HD22 1 
ATOM   7826 N N    . GLY B 1 215 ? -0.79998  -12.39086 -25.69417 1.000 38.23380  ? 215 GLY B N    1 
ATOM   7827 C CA   . GLY B 1 215 ? -0.36117  -13.56685 -24.97571 1.000 43.96230  ? 215 GLY B CA   1 
ATOM   7828 C C    . GLY B 1 215 ? -1.11656  -14.84474 -25.27300 1.000 49.67130  ? 215 GLY B C    1 
ATOM   7829 O O    . GLY B 1 215 ? -0.70990  -15.90723 -24.78639 1.000 49.95014  ? 215 GLY B O    1 
ATOM   7830 H H    . GLY B 1 215 ? -0.41512  -12.28648 -26.45613 1.000 45.87434  ? 215 GLY B H    1 
ATOM   7831 H HA2  . GLY B 1 215 ? 0.57226   -13.72448 -25.18727 1.000 52.74854  ? 215 GLY B HA2  1 
ATOM   7832 H HA3  . GLY B 1 215 ? -0.44462  -13.39379 -24.02492 1.000 52.74854  ? 215 GLY B HA3  1 
ATOM   7833 N N    . ASP B 1 216 ? -2.19619  -14.78614 -26.04818 1.000 41.32889  ? 216 ASP B N    1 
ATOM   7834 C CA   . ASP B 1 216 ? -2.99372  -15.97107 -26.36626 1.000 48.08926  ? 216 ASP B CA   1 
ATOM   7835 C C    . ASP B 1 216 ? -2.41590  -16.60575 -27.62835 1.000 57.77526  ? 216 ASP B C    1 
ATOM   7836 O O    . ASP B 1 216 ? -2.75372  -16.21150 -28.74763 1.000 54.54940  ? 216 ASP B O    1 
ATOM   7837 C CB   . ASP B 1 216 ? -4.45810  -15.58729 -26.53796 1.000 51.72845  ? 216 ASP B CB   1 
ATOM   7838 C CG   . ASP B 1 216 ? -5.40666  -16.63797 -26.00063 1.000 55.77247  ? 216 ASP B CG   1 
ATOM   7839 O OD1  . ASP B 1 216 ? -4.95816  -17.53991 -25.26047 1.000 62.60973  ? 216 ASP B OD1  1 
ATOM   7840 O OD2  . ASP B 1 216 ? -6.61048  -16.55721 -26.32084 1.000 61.21006  ? 216 ASP B OD2  1 
ATOM   7841 H H    . ASP B 1 216 ? -2.49204  -14.06282 -26.40717 1.000 49.58844  ? 216 ASP B H    1 
ATOM   7842 H HA   . ASP B 1 216 ? -2.92931  -16.61864 -25.64696 1.000 57.70088  ? 216 ASP B HA   1 
ATOM   7843 H HB2  . ASP B 1 216 ? -4.62591  -14.75969 -26.06066 1.000 62.06792  ? 216 ASP B HB2  1 
ATOM   7844 H HB3  . ASP B 1 216 ? -4.64520  -15.46938 -27.48242 1.000 62.06792  ? 216 ASP B HB3  1 
ATOM   7845 N N    . ARG B 1 217 ? -1.55225  -17.60858 -27.44740 1.000 55.71225  ? 217 ARG B N    1 
ATOM   7846 C CA   . ARG B 1 217 ? -0.72756  -18.13883 -28.52593 1.000 46.41724  ? 217 ARG B CA   1 
ATOM   7847 C C    . ARG B 1 217 ? -1.04966  -19.58124 -28.90388 1.000 52.30012  ? 217 ARG B C    1 
ATOM   7848 O O    . ARG B 1 217 ? -0.46272  -20.09816 -29.86119 1.000 47.41685  ? 217 ARG B O    1 
ATOM   7849 C CB   . ARG B 1 217 ? 0.75767   -18.05330 -28.13613 1.000 54.72485  ? 217 ARG B CB   1 
ATOM   7850 C CG   . ARG B 1 217 ? 1.21826   -16.69400 -27.61891 1.000 63.96882  ? 217 ARG B CG   1 
ATOM   7851 C CD   . ARG B 1 217 ? 2.65767   -16.74527 -27.08526 1.000 68.67316  ? 217 ARG B CD   1 
ATOM   7852 N NE   . ARG B 1 217 ? 2.73730   -17.13703 -25.67867 1.000 76.99342  ? 217 ARG B NE   1 
ATOM   7853 C CZ   . ARG B 1 217 ? 3.13826   -18.32285 -25.23041 1.000 67.68615  ? 217 ARG B CZ   1 
ATOM   7854 N NH1  . ARG B 1 217 ? 3.51013   -19.29050 -26.05348 1.000 62.40651  ? 217 ARG B NH1  1 
ATOM   7855 N NH2  . ARG B 1 217 ? 3.17092   -18.54246 -23.91904 1.000 58.90968  ? 217 ARG B NH2  1 
ATOM   7856 H H    . ARG B 1 217 ? -1.42678  -18.00278 -26.69343 1.000 66.84847  ? 217 ARG B H    1 
ATOM   7857 H HA   . ARG B 1 217 ? -0.88369  -17.59056 -29.31073 1.000 55.69446  ? 217 ARG B HA   1 
ATOM   7858 H HB2  . ARG B 1 217 ? 0.92798   -18.70252 -27.43584 1.000 65.66359  ? 217 ARG B HB2  1 
ATOM   7859 H HB3  . ARG B 1 217 ? 1.29174   -18.26156 -28.91863 1.000 65.66359  ? 217 ARG B HB3  1 
ATOM   7860 H HG2  . ARG B 1 217 ? 1.18527   -16.04826 -28.34197 1.000 76.75636  ? 217 ARG B HG2  1 
ATOM   7861 H HG3  . ARG B 1 217 ? 0.63617   -16.41246 -26.89586 1.000 76.75636  ? 217 ARG B HG3  1 
ATOM   7862 H HD2  . ARG B 1 217 ? 3.16239   -17.39154 -27.60343 1.000 82.40156  ? 217 ARG B HD2  1 
ATOM   7863 H HD3  . ARG B 1 217 ? 3.05696   -15.86557 -27.17246 1.000 82.40156  ? 217 ARG B HD3  1 
ATOM   7864 H HE   . ARG B 1 217 ? 2.50552   -16.55181 -25.09267 1.000 92.38587  ? 217 ARG B HE   1 
ATOM   7865 H HH11 . ARG B 1 217 ? 3.49642   -19.16091 -26.90355 1.000 74.88158  ? 217 ARG B HH11 1 
ATOM   7866 H HH12 . ARG B 1 217 ? 3.76545   -20.04878 -25.73817 1.000 74.88158  ? 217 ARG B HH12 1 
ATOM   7867 H HH21 . ARG B 1 217 ? 2.93451   -17.92149 -23.37304 1.000 70.68538  ? 217 ARG B HH21 1 
ATOM   7868 H HH22 . ARG B 1 217 ? 3.42844   -19.30542 -23.61710 1.000 70.68538  ? 217 ARG B HH22 1 
ATOM   7869 N N    . TRP B 1 218 ? -1.96846  -20.24301 -28.19622 1.000 48.62231  ? 218 TRP B N    1 
ATOM   7870 C CA   . TRP B 1 218 ? -2.10353  -21.69247 -28.32161 1.000 52.54803  ? 218 TRP B CA   1 
ATOM   7871 C C    . TRP B 1 218 ? -2.38079  -22.15604 -29.74900 1.000 52.55760  ? 218 TRP B C    1 
ATOM   7872 O O    . TRP B 1 218 ? -2.13511  -23.32624 -30.06369 1.000 52.91664  ? 218 TRP B O    1 
ATOM   7873 C CB   . TRP B 1 218 ? -3.21532  -22.19454 -27.39694 1.000 43.82605  ? 218 TRP B CB   1 
ATOM   7874 C CG   . TRP B 1 218 ? -4.57205  -21.66429 -27.73050 1.000 45.14918  ? 218 TRP B CG   1 
ATOM   7875 C CD1  . TRP B 1 218 ? -5.18945  -20.58338 -27.17147 1.000 54.08522  ? 218 TRP B CD1  1 
ATOM   7876 C CD2  . TRP B 1 218 ? -5.48698  -22.19420 -28.69593 1.000 45.15282  ? 218 TRP B CD2  1 
ATOM   7877 N NE1  . TRP B 1 218 ? -6.43196  -20.40659 -27.72937 1.000 50.82218  ? 218 TRP B NE1  1 
ATOM   7878 C CE2  . TRP B 1 218 ? -6.63881  -21.38250 -28.66858 1.000 52.33617  ? 218 TRP B CE2  1 
ATOM   7879 C CE3  . TRP B 1 218 ? -5.44512  -23.27666 -29.58021 1.000 47.52237  ? 218 TRP B CE3  1 
ATOM   7880 C CZ2  . TRP B 1 218 ? -7.73666  -21.61631 -29.49447 1.000 55.48581  ? 218 TRP B CZ2  1 
ATOM   7881 C CZ3  . TRP B 1 218 ? -6.53623  -23.50801 -30.39750 1.000 50.26395  ? 218 TRP B CZ3  1 
ATOM   7882 C CH2  . TRP B 1 218 ? -7.66791  -22.68339 -30.34709 1.000 49.97321  ? 218 TRP B CH2  1 
ATOM   7883 H H    . TRP B 1 218 ? -2.51842  -19.87977 -27.64378 1.000 58.34055  ? 218 TRP B H    1 
ATOM   7884 H HA   . TRP B 1 218 ? -1.26316  -22.09196 -28.04758 1.000 63.05140  ? 218 TRP B HA   1 
ATOM   7885 H HB2  . TRP B 1 218 ? -3.25464  -23.16198 -27.45525 1.000 52.58503  ? 218 TRP B HB2  1 
ATOM   7886 H HB3  . TRP B 1 218 ? -3.00897  -21.92506 -26.48826 1.000 52.58503  ? 218 TRP B HB3  1 
ATOM   7887 H HD1  . TRP B 1 218 ? -4.82205  -20.04440 -26.50859 1.000 64.89603  ? 218 TRP B HD1  1 
ATOM   7888 H HE1  . TRP B 1 218 ? -6.98914  -19.78488 -27.52292 1.000 60.98038  ? 218 TRP B HE1  1 
ATOM   7889 H HE3  . TRP B 1 218 ? -4.69847  -23.82983 -29.61786 1.000 57.02062  ? 218 TRP B HE3  1 
ATOM   7890 H HZ2  . TRP B 1 218 ? -8.48719  -21.06782 -29.46689 1.000 66.57674  ? 218 TRP B HZ2  1 
ATOM   7891 H HZ3  . TRP B 1 218 ? -6.51864  -24.22364 -30.99119 1.000 60.31051  ? 218 TRP B HZ3  1 
ATOM   7892 H HH2  . TRP B 1 218 ? -8.38850  -22.86579 -30.90600 1.000 59.96163  ? 218 TRP B HH2  1 
ATOM   7893 N N    . PHE B 1 219 ? -2.87903  -21.27906 -30.61806 1.000 48.89734  ? 219 PHE B N    1 
ATOM   7894 C CA   . PHE B 1 219 ? -3.26670  -21.66733 -31.96845 1.000 45.27652  ? 219 PHE B CA   1 
ATOM   7895 C C    . PHE B 1 219 ? -2.13243  -21.55237 -32.97892 1.000 42.27899  ? 219 PHE B C    1 
ATOM   7896 O O    . PHE B 1 219 ? -2.29657  -21.98953 -34.12374 1.000 42.45786  ? 219 PHE B O    1 
ATOM   7897 C CB   . PHE B 1 219 ? -4.44890  -20.80960 -32.44158 1.000 48.48170  ? 219 PHE B CB   1 
ATOM   7898 C CG   . PHE B 1 219 ? -4.19390  -19.33033 -32.35208 1.000 43.86838  ? 219 PHE B CG   1 
ATOM   7899 C CD1  . PHE B 1 219 ? -4.50639  -18.62901 -31.19753 1.000 47.15127  ? 219 PHE B CD1  1 
ATOM   7900 C CD2  . PHE B 1 219 ? -3.62905  -18.64390 -33.41354 1.000 45.03558  ? 219 PHE B CD2  1 
ATOM   7901 C CE1  . PHE B 1 219 ? -4.26600  -17.27148 -31.10602 1.000 50.69336  ? 219 PHE B CE1  1 
ATOM   7902 C CE2  . PHE B 1 219 ? -3.38692  -17.28160 -33.32801 1.000 44.70430  ? 219 PHE B CE2  1 
ATOM   7903 C CZ   . PHE B 1 219 ? -3.70413  -16.59716 -32.17280 1.000 44.25939  ? 219 PHE B CZ   1 
ATOM   7904 H H    . PHE B 1 219 ? -3.00273  -20.44556 -30.44609 1.000 58.67057  ? 219 PHE B H    1 
ATOM   7905 H HA   . PHE B 1 219 ? -3.55147  -22.59441 -31.95025 1.000 54.32559  ? 219 PHE B HA   1 
ATOM   7906 H HB2  . PHE B 1 219 ? -4.63795  -21.02246 -33.36886 1.000 58.17181  ? 219 PHE B HB2  1 
ATOM   7907 H HB3  . PHE B 1 219 ? -5.22142  -21.01131 -31.89074 1.000 58.17181  ? 219 PHE B HB3  1 
ATOM   7908 H HD1  . PHE B 1 219 ? -4.88269  -19.07818 -30.47535 1.000 56.57530  ? 219 PHE B HD1  1 
ATOM   7909 H HD2  . PHE B 1 219 ? -3.40961  -19.10187 -34.19265 1.000 54.03647  ? 219 PHE B HD2  1 
ATOM   7910 H HE1  . PHE B 1 219 ? -4.48228  -16.81206 -30.32688 1.000 60.82580  ? 219 PHE B HE1  1 
ATOM   7911 H HE2  . PHE B 1 219 ? -3.01105  -16.82950 -34.04859 1.000 53.63893  ? 219 PHE B HE2  1 
ATOM   7912 H HZ   . PHE B 1 219 ? -3.54004  -15.68375 -32.11241 1.000 53.10503  ? 219 PHE B HZ   1 
ATOM   7913 N N    . LEU B 1 220 ? -0.99883  -20.97165 -32.60029 1.000 44.97953  ? 220 LEU B N    1 
ATOM   7914 C CA   . LEU B 1 220 ? 0.10605   -20.84675 -33.53778 1.000 53.93842  ? 220 LEU B CA   1 
ATOM   7915 C C    . LEU B 1 220 ? 0.68245   -22.21869 -33.86499 1.000 59.72930  ? 220 LEU B C    1 
ATOM   7916 O O    . LEU B 1 220 ? 0.64263   -23.14706 -33.05242 1.000 64.11219  ? 220 LEU B O    1 
ATOM   7917 C CB   . LEU B 1 220 ? 1.20529   -19.94956 -32.96795 1.000 51.94036  ? 220 LEU B CB   1 
ATOM   7918 C CG   . LEU B 1 220 ? 0.87255   -18.47433 -32.74307 1.000 42.08754  ? 220 LEU B CG   1 
ATOM   7919 C CD1  . LEU B 1 220 ? 2.04748   -17.76575 -32.09058 1.000 44.24654  ? 220 LEU B CD1  1 
ATOM   7920 C CD2  . LEU B 1 220 ? 0.49025   -17.78703 -34.04429 1.000 43.92171  ? 220 LEU B CD2  1 
ATOM   7921 H H    . LEU B 1 220 ? -0.84796  -20.64734 -31.81820 1.000 53.96920  ? 220 LEU B H    1 
ATOM   7922 H HA   . LEU B 1 220 ? -0.21632  -20.44008 -34.35729 1.000 64.71988  ? 220 LEU B HA   1 
ATOM   7923 H HB2  . LEU B 1 220 ? 1.46624   -20.31207 -32.10691 1.000 62.32220  ? 220 LEU B HB2  1 
ATOM   7924 H HB3  . LEU B 1 220 ? 1.95664   -19.97677 -33.58085 1.000 62.32220  ? 220 LEU B HB3  1 
ATOM   7925 H HG   . LEU B 1 220 ? 0.10727   -18.41627 -32.14989 1.000 50.49882  ? 220 LEU B HG   1 
ATOM   7926 H HD11 . LEU B 1 220 ? 2.84589   -17.92766 -32.61711 1.000 53.08962  ? 220 LEU B HD11 1 
ATOM   7927 H HD12 . LEU B 1 220 ? 1.86216   -16.81430 -32.05479 1.000 53.08962  ? 220 LEU B HD12 1 
ATOM   7928 H HD13 . LEU B 1 220 ? 2.16706   -18.11346 -31.19297 1.000 53.08962  ? 220 LEU B HD13 1 
ATOM   7929 H HD21 . LEU B 1 220 ? 1.13280   -18.02854 -34.72964 1.000 52.69983  ? 220 LEU B HD21 1 
ATOM   7930 H HD22 . LEU B 1 220 ? -0.39743  -18.07761 -34.30597 1.000 52.69983  ? 220 LEU B HD22 1 
ATOM   7931 H HD23 . LEU B 1 220 ? 0.49717   -16.82667 -33.90806 1.000 52.69983  ? 220 LEU B HD23 1 
ATOM   7932 N N    . ASN B 1 221 ? 1.21964   -22.34068 -35.07576 1.000 64.21880  ? 221 ASN B N    1 
ATOM   7933 C CA   . ASN B 1 221 ? 1.93436   -23.54403 -35.46963 1.000 63.85676  ? 221 ASN B CA   1 
ATOM   7934 C C    . ASN B 1 221 ? 3.01426   -23.17751 -36.47618 1.000 76.36178  ? 221 ASN B C    1 
ATOM   7935 O O    . ASN B 1 221 ? 2.90392   -22.18076 -37.19592 1.000 78.49922  ? 221 ASN B O    1 
ATOM   7936 C CB   . ASN B 1 221 ? 0.99120   -24.60253 -36.05820 1.000 61.68193  ? 221 ASN B CB   1 
ATOM   7937 C CG   . ASN B 1 221 ? 0.18774   -24.08901 -37.23825 1.000 64.70854  ? 221 ASN B CG   1 
ATOM   7938 O OD1  . ASN B 1 221 ? 0.67439   -23.30152 -38.04987 1.000 72.48795  ? 221 ASN B OD1  1 
ATOM   7939 N ND2  . ASN B 1 221 ? -1.05482  -24.54161 -37.33982 1.000 70.75104  ? 221 ASN B ND2  1 
ATOM   7940 H H    . ASN B 1 221 ? 1.18214   -21.73695 -35.68707 1.000 77.05633  ? 221 ASN B H    1 
ATOM   7941 H HA   . ASN B 1 221 ? 2.36632   -23.92812 -34.69067 1.000 76.62188  ? 221 ASN B HA   1 
ATOM   7942 H HB2  . ASN B 1 221 ? 1.51663   -25.35961 -36.36093 1.000 74.01209  ? 221 ASN B HB2  1 
ATOM   7943 H HB3  . ASN B 1 221 ? 0.36693   -24.88524 -35.37171 1.000 74.01209  ? 221 ASN B HB3  1 
ATOM   7944 H HD21 . ASN B 1 221 ? -1.55486  -24.28299 -37.98996 1.000 84.89502  ? 221 ASN B HD21 1 
ATOM   7945 H HD22 . ASN B 1 221 ? -1.36047  -25.09370 -36.75555 1.000 84.89502  ? 221 ASN B HD22 1 
ATOM   7946 N N    . ARG B 1 222 ? 4.06607   -23.99576 -36.51052 1.000 84.24009  ? 222 ARG B N    1 
ATOM   7947 C CA   . ARG B 1 222 ? 5.13242   -23.84811 -37.49336 1.000 82.36001  ? 222 ARG B CA   1 
ATOM   7948 C C    . ARG B 1 222 ? 4.73123   -24.37418 -38.86456 1.000 83.07833  ? 222 ARG B C    1 
ATOM   7949 O O    . ARG B 1 222 ? 5.56691   -24.39235 -39.77710 1.000 80.00680  ? 222 ARG B O    1 
ATOM   7950 C CB   . ARG B 1 222 ? 6.39709   -24.56502 -37.01007 1.000 67.80716  ? 222 ARG B CB   1 
ATOM   7951 H H    . ARG B 1 222 ? 4.18435   -24.65181 -35.96720 1.000 101.08188 ? 222 ARG B H    1 
ATOM   7952 H HA   . ARG B 1 222 ? 5.34908   -22.90703 -37.58461 1.000 98.82578  ? 222 ARG B HA   1 
ATOM   7953 N N    . PHE B 1 223 ? 3.48080   -24.79920 -39.02779 1.000 81.33435  ? 223 PHE B N    1 
ATOM   7954 C CA   . PHE B 1 223 ? 2.99693   -25.22339 -40.32994 1.000 72.43051  ? 223 PHE B CA   1 
ATOM   7955 C C    . PHE B 1 223 ? 3.05872   -24.06310 -41.31610 1.000 74.18046  ? 223 PHE B C    1 
ATOM   7956 O O    . PHE B 1 223 ? 3.15986   -22.89166 -40.94029 1.000 72.83515  ? 223 PHE B O    1 
ATOM   7957 C CB   . PHE B 1 223 ? 1.56618   -25.74959 -40.22782 1.000 73.46908  ? 223 PHE B CB   1 
ATOM   7958 C CG   . PHE B 1 223 ? 1.47451   -27.15412 -39.71072 1.000 70.19586  ? 223 PHE B CG   1 
ATOM   7959 C CD1  . PHE B 1 223 ? 1.95506   -27.47564 -38.45302 1.000 74.22743  ? 223 PHE B CD1  1 
ATOM   7960 C CD2  . PHE B 1 223 ? 0.90054   -28.15161 -40.48017 1.000 68.67954  ? 223 PHE B CD2  1 
ATOM   7961 C CE1  . PHE B 1 223 ? 1.87216   -28.76718 -37.97562 1.000 71.89187  ? 223 PHE B CE1  1 
ATOM   7962 C CE2  . PHE B 1 223 ? 0.81191   -29.44400 -40.00822 1.000 72.19767  ? 223 PHE B CE2  1 
ATOM   7963 C CZ   . PHE B 1 223 ? 1.29836   -29.75295 -38.75358 1.000 74.52829  ? 223 PHE B CZ   1 
ATOM   7964 H H    . PHE B 1 223 ? 2.89600   -24.85023 -38.39930 1.000 97.59499  ? 223 PHE B H    1 
ATOM   7965 H HA   . PHE B 1 223 ? 3.55462   -25.94284 -40.66502 1.000 86.91039  ? 223 PHE B HA   1 
ATOM   7966 H HB2  . PHE B 1 223 ? 1.06622   -25.17853 -39.62381 1.000 88.15667  ? 223 PHE B HB2  1 
ATOM   7967 H HB3  . PHE B 1 223 ? 1.16373   -25.73214 -41.11022 1.000 88.15667  ? 223 PHE B HB3  1 
ATOM   7968 H HD1  . PHE B 1 223 ? 2.33806   -26.81356 -37.92401 1.000 89.06669  ? 223 PHE B HD1  1 
ATOM   7969 H HD2  . PHE B 1 223 ? 0.57082   -27.94752 -41.32547 1.000 82.40923  ? 223 PHE B HD2  1 
ATOM   7970 H HE1  . PHE B 1 223 ? 2.20226   -28.97360 -37.13103 1.000 86.26402  ? 223 PHE B HE1  1 
ATOM   7971 H HE2  . PHE B 1 223 ? 0.42516   -30.10645 -40.53403 1.000 86.63098  ? 223 PHE B HE2  1 
ATOM   7972 H HZ   . PHE B 1 223 ? 1.23960   -30.62393 -38.43290 1.000 89.42772  ? 223 PHE B HZ   1 
ATOM   7973 N N    . THR B 1 224 ? 2.99982   -24.40540 -42.59737 1.000 77.62654  ? 224 THR B N    1 
ATOM   7974 C CA   . THR B 1 224 ? 3.08160   -23.43010 -43.66946 1.000 76.16955  ? 224 THR B CA   1 
ATOM   7975 C C    . THR B 1 224 ? 1.96084   -23.68199 -44.66657 1.000 69.20398  ? 224 THR B C    1 
ATOM   7976 O O    . THR B 1 224 ? 1.21761   -24.66252 -44.57212 1.000 72.79841  ? 224 THR B O    1 
ATOM   7977 C CB   . THR B 1 224 ? 4.44108   -23.49485 -44.37410 1.000 80.06434  ? 224 THR B CB   1 
ATOM   7978 O OG1  . THR B 1 224 ? 4.53161   -24.70899 -45.13037 1.000 77.21341  ? 224 THR B OG1  1 
ATOM   7979 C CG2  . THR B 1 224 ? 5.56175   -23.46062 -43.35281 1.000 74.80361  ? 224 THR B CG2  1 
ATOM   7980 H H    . THR B 1 224 ? 2.91070   -25.21494 -42.87362 1.000 93.14562  ? 224 THR B H    1 
ATOM   7981 H HA   . THR B 1 224 ? 2.96774   -22.53921 -43.30304 1.000 91.39724  ? 224 THR B HA   1 
ATOM   7982 H HB   . THR B 1 224 ? 4.53736   -22.73456 -44.96874 1.000 96.07098  ? 224 THR B HB   1 
ATOM   7983 H HG1  . THR B 1 224 ? 4.62068   -24.53292 -45.94686 1.000 92.64987  ? 224 THR B HG1  1 
ATOM   7984 H HG21 . THR B 1 224 ? 6.40018   -23.23943 -43.78757 1.000 89.75811  ? 224 THR B HG21 1 
ATOM   7985 H HG22 . THR B 1 224 ? 5.37277   -22.79281 -42.67516 1.000 89.75811  ? 224 THR B HG22 1 
ATOM   7986 H HG23 . THR B 1 224 ? 5.64775   -24.32716 -42.92548 1.000 89.75811  ? 224 THR B HG23 1 
ATOM   7987 N N    . THR B 1 225 ? 1.84767   -22.77498 -45.63035 1.000 63.25811  ? 225 THR B N    1 
ATOM   7988 C CA   . THR B 1 225 ? 0.86234   -22.89121 -46.69419 1.000 67.29778  ? 225 THR B CA   1 
ATOM   7989 C C    . THR B 1 225 ? 1.18316   -21.83959 -47.74216 1.000 60.30937  ? 225 THR B C    1 
ATOM   7990 O O    . THR B 1 225 ? 1.91408   -20.88000 -47.47913 1.000 59.33069  ? 225 THR B O    1 
ATOM   7991 C CB   . THR B 1 225 ? -0.56975  -22.71053 -46.17415 1.000 75.75363  ? 225 THR B CB   1 
ATOM   7992 O OG1  . THR B 1 225 ? -1.49779  -22.85303 -47.25842 1.000 70.36568  ? 225 THR B OG1  1 
ATOM   7993 C CG2  . THR B 1 225 ? -0.74629  -21.33354 -45.52904 1.000 62.19487  ? 225 THR B CG2  1 
ATOM   7994 H H    . THR B 1 225 ? 2.33903   -22.07169 -45.68995 1.000 75.90351  ? 225 THR B H    1 
ATOM   7995 H HA   . THR B 1 225 ? 0.92453   -23.77044 -47.09914 1.000 80.75110  ? 225 THR B HA   1 
ATOM   7996 H HB   . THR B 1 225 ? -0.75313  -23.38425 -45.50082 1.000 90.89812  ? 225 THR B HB   1 
ATOM   7997 H HG1  . THR B 1 225 ? -1.56951  -22.12580 -47.67266 1.000 84.43259  ? 225 THR B HG1  1 
ATOM   7998 H HG21 . THR B 1 225 ? -0.11094  -21.22269 -44.80452 1.000 74.62761  ? 225 THR B HG21 1 
ATOM   7999 H HG22 . THR B 1 225 ? -0.59741  -20.63710 -46.18761 1.000 74.62761  ? 225 THR B HG22 1 
ATOM   8000 H HG23 . THR B 1 225 ? -1.64531  -21.24557 -45.17559 1.000 74.62761  ? 225 THR B HG23 1 
ATOM   8001 N N    . THR B 1 226 ? 0.64064   -22.04093 -48.93472 1.000 69.59690  ? 226 THR B N    1 
ATOM   8002 C CA   . THR B 1 226 ? 0.67585   -21.03243 -49.97934 1.000 63.92420  ? 226 THR B CA   1 
ATOM   8003 C C    . THR B 1 226 ? -0.65456  -20.29113 -49.99847 1.000 58.61595  ? 226 THR B C    1 
ATOM   8004 O O    . THR B 1 226 ? -1.67039  -20.77231 -49.48848 1.000 53.93543  ? 226 THR B O    1 
ATOM   8005 C CB   . THR B 1 226 ? 0.95049   -21.65391 -51.35216 1.000 64.46805  ? 226 THR B CB   1 
ATOM   8006 O OG1  . THR B 1 226 ? -0.28777  -22.02424 -51.97176 1.000 53.21487  ? 226 THR B OG1  1 
ATOM   8007 C CG2  . THR B 1 226 ? 1.84778   -22.88667 -51.21884 1.000 63.21717  ? 226 THR B CG2  1 
ATOM   8008 H H    . THR B 1 226 ? 0.24015   -22.76634 -49.16493 1.000 83.51005  ? 226 THR B H    1 
ATOM   8009 H HA   . THR B 1 226 ? 1.39389   -20.40450 -49.80321 1.000 76.70281  ? 226 THR B HA   1 
ATOM   8010 H HB   . THR B 1 226 ? 1.40770   -21.00739 -51.91239 1.000 77.35543  ? 226 THR B HB   1 
ATOM   8011 H HG1  . THR B 1 226 ? -0.19305  -22.05755 -52.80573 1.000 63.85162  ? 226 THR B HG1  1 
ATOM   8012 H HG21 . THR B 1 226 ? 2.25779   -23.09256 -52.07347 1.000 75.85438  ? 226 THR B HG21 1 
ATOM   8013 H HG22 . THR B 1 226 ? 2.54617   -22.71970 -50.56671 1.000 75.85438  ? 226 THR B HG22 1 
ATOM   8014 H HG23 . THR B 1 226 ? 1.32285   -23.64937 -50.92964 1.000 75.85438  ? 226 THR B HG23 1 
ATOM   8015 N N    . LEU B 1 227 ? -0.63279  -19.09762 -50.58877 1.000 53.28463  ? 227 LEU B N    1 
ATOM   8016 C CA   . LEU B 1 227 ? -1.85651  -18.31266 -50.69706 1.000 50.28147  ? 227 LEU B CA   1 
ATOM   8017 C C    . LEU B 1 227 ? -2.93135  -19.08539 -51.44970 1.000 57.90740  ? 227 LEU B C    1 
ATOM   8018 O O    . LEU B 1 227 ? -4.12163  -18.98324 -51.12894 1.000 58.38827  ? 227 LEU B O    1 
ATOM   8019 C CB   . LEU B 1 227 ? -1.54894  -16.98686 -51.38700 1.000 52.45368  ? 227 LEU B CB   1 
ATOM   8020 C CG   . LEU B 1 227 ? -2.42269  -15.77603 -51.06969 1.000 54.10213  ? 227 LEU B CG   1 
ATOM   8021 C CD1  . LEU B 1 227 ? -2.65527  -15.60785 -49.57917 1.000 54.29700  ? 227 LEU B CD1  1 
ATOM   8022 C CD2  . LEU B 1 227 ? -1.74877  -14.54069 -51.64292 1.000 53.39655  ? 227 LEU B CD2  1 
ATOM   8023 H H    . LEU B 1 227 ? 0.06495   -18.72691 -50.92837 1.000 63.93533  ? 227 LEU B H    1 
ATOM   8024 H HA   . LEU B 1 227 ? -2.19904  -18.11746 -49.81079 1.000 60.33154  ? 227 LEU B HA   1 
ATOM   8025 H HB2  . LEU B 1 227 ? -0.64050  -16.74003 -51.15312 1.000 62.93818  ? 227 LEU B HB2  1 
ATOM   8026 H HB3  . LEU B 1 227 ? -1.61725  -17.13291 -52.34351 1.000 62.93818  ? 227 LEU B HB3  1 
ATOM   8027 H HG   . LEU B 1 227 ? -3.29857  -15.89958 -51.46777 1.000 64.91633  ? 227 LEU B HG   1 
ATOM   8028 H HD11 . LEU B 1 227 ? -1.81405  -15.73159 -49.11234 1.000 65.15017  ? 227 LEU B HD11 1 
ATOM   8029 H HD12 . LEU B 1 227 ? -2.99845  -14.71617 -49.41172 1.000 65.15017  ? 227 LEU B HD12 1 
ATOM   8030 H HD13 . LEU B 1 227 ? -3.29849  -16.27083 -49.28313 1.000 65.15017  ? 227 LEU B HD13 1 
ATOM   8031 H HD21 . LEU B 1 227 ? -0.90526  -14.39998 -51.18510 1.000 64.06964  ? 227 LEU B HD21 1 
ATOM   8032 H HD22 . LEU B 1 227 ? -1.59211  -14.67735 -52.59038 1.000 64.06964  ? 227 LEU B HD22 1 
ATOM   8033 H HD23 . LEU B 1 227 ? -2.32873  -13.77450 -51.51068 1.000 64.06964  ? 227 LEU B HD23 1 
ATOM   8034 N N    . ASN B 1 228 ? -2.53121  -19.87540 -52.44632 1.000 62.32508  ? 228 ASN B N    1 
ATOM   8035 C CA   . ASN B 1 228 ? -3.49807  -20.66892 -53.19404 1.000 57.59194  ? 228 ASN B CA   1 
ATOM   8036 C C    . ASN B 1 228 ? -3.96844  -21.86777 -52.37653 1.000 53.61291  ? 228 ASN B C    1 
ATOM   8037 O O    . ASN B 1 228 ? -5.14682  -22.23934 -52.43262 1.000 58.85756  ? 228 ASN B O    1 
ATOM   8038 C CB   . ASN B 1 228 ? -2.88362  -21.11826 -54.52087 1.000 64.03925  ? 228 ASN B CB   1 
ATOM   8039 C CG   . ASN B 1 228 ? -3.89864  -21.17470 -55.64372 1.000 55.54309  ? 228 ASN B CG   1 
ATOM   8040 O OD1  . ASN B 1 228 ? -4.05233  -20.21934 -56.40511 1.000 54.16240  ? 228 ASN B OD1  1 
ATOM   8041 N ND2  . ASN B 1 228 ? -4.59921  -22.29389 -55.75138 1.000 71.80300  ? 228 ASN B ND2  1 
ATOM   8042 H H    . ASN B 1 228 ? -1.71604  -19.96728 -52.70449 1.000 74.78387  ? 228 ASN B H    1 
ATOM   8043 H HA   . ASN B 1 228 ? -4.27433  -20.12493 -53.39993 1.000 69.10410  ? 228 ASN B HA   1 
ATOM   8044 H HB2  . ASN B 1 228 ? -2.18804  -20.49209 -54.77579 1.000 76.84087  ? 228 ASN B HB2  1 
ATOM   8045 H HB3  . ASN B 1 228 ? -2.50731  -22.00553 -54.41111 1.000 76.84087  ? 228 ASN B HB3  1 
ATOM   8046 H HD21 . ASN B 1 228 ? -4.46526  -22.93979 -55.19960 1.000 86.15737  ? 228 ASN B HD21 1 
ATOM   8047 H HD22 . ASN B 1 228 ? -5.18795  -22.37454 -56.37306 1.000 86.15737  ? 228 ASN B HD22 1 
ATOM   8048 N N    . ASP B 1 229 ? -3.06107  -22.48402 -51.61483 1.000 57.43269  ? 229 ASP B N    1 
ATOM   8049 C CA   . ASP B 1 229 ? -3.46183  -23.55389 -50.70702 1.000 63.67239  ? 229 ASP B CA   1 
ATOM   8050 C C    . ASP B 1 229 ? -4.50135  -23.05365 -49.71357 1.000 60.33251  ? 229 ASP B C    1 
ATOM   8051 O O    . ASP B 1 229 ? -5.57533  -23.64764 -49.56127 1.000 61.30580  ? 229 ASP B O    1 
ATOM   8052 C CB   . ASP B 1 229 ? -2.24465  -24.10093 -49.95674 1.000 61.96576  ? 229 ASP B CB   1 
ATOM   8053 C CG   . ASP B 1 229 ? -1.44630  -25.10299 -50.76927 1.000 73.84787  ? 229 ASP B CG   1 
ATOM   8054 O OD1  . ASP B 1 229 ? -1.99429  -25.67280 -51.73865 1.000 72.49138  ? 229 ASP B OD1  1 
ATOM   8055 O OD2  . ASP B 1 229 ? -0.26739  -25.33265 -50.41940 1.000 75.79490  ? 229 ASP B OD2  1 
ATOM   8056 H H    . ASP B 1 229 ? -2.22041  -22.30287 -51.60639 1.000 68.91300  ? 229 ASP B H    1 
ATOM   8057 H HA   . ASP B 1 229 ? -3.84517  -24.27538 -51.22989 1.000 76.40064  ? 229 ASP B HA   1 
ATOM   8058 H HB2  . ASP B 1 229 ? -1.65644  -23.36347 -49.73078 1.000 74.35269  ? 229 ASP B HB2  1 
ATOM   8059 H HB3  . ASP B 1 229 ? -2.54616  -24.54446 -49.14848 1.000 74.35269  ? 229 ASP B HB3  1 
ATOM   8060 N N    . PHE B 1 230 ? -4.19098  -21.95234 -49.02565 1.000 62.48555  ? 230 PHE B N    1 
ATOM   8061 C CA   . PHE B 1 230 ? -5.09571  -21.42529 -48.01132 1.000 57.76153  ? 230 PHE B CA   1 
ATOM   8062 C C    . PHE B 1 230 ? -6.42085  -20.99358 -48.62633 1.000 53.35373  ? 230 PHE B C    1 
ATOM   8063 O O    . PHE B 1 230 ? -7.49214  -21.30221 -48.09085 1.000 52.23283  ? 230 PHE B O    1 
ATOM   8064 C CB   . PHE B 1 230 ? -4.42426  -20.25725 -47.28536 1.000 59.80547  ? 230 PHE B CB   1 
ATOM   8065 C CG   . PHE B 1 230 ? -5.31250  -19.56723 -46.29302 1.000 59.93989  ? 230 PHE B CG   1 
ATOM   8066 C CD1  . PHE B 1 230 ? -6.12263  -18.51396 -46.68523 1.000 53.16024  ? 230 PHE B CD1  1 
ATOM   8067 C CD2  . PHE B 1 230 ? -5.33758  -19.96951 -44.96822 1.000 46.20118  ? 230 PHE B CD2  1 
ATOM   8068 C CE1  . PHE B 1 230 ? -6.94404  -17.88025 -45.77801 1.000 49.87405  ? 230 PHE B CE1  1 
ATOM   8069 C CE2  . PHE B 1 230 ? -6.15448  -19.33568 -44.05515 1.000 57.26418  ? 230 PHE B CE2  1 
ATOM   8070 C CZ   . PHE B 1 230 ? -6.95978  -18.28956 -44.46125 1.000 56.07425  ? 230 PHE B CZ   1 
ATOM   8071 H H    . PHE B 1 230 ? -3.46849  -21.49721 -49.12788 1.000 74.97643  ? 230 PHE B H    1 
ATOM   8072 H HA   . PHE B 1 230 ? -5.28600  -22.11799 -47.35950 1.000 69.30760  ? 230 PHE B HA   1 
ATOM   8073 H HB2  . PHE B 1 230 ? -3.65018  -20.59211 -46.80622 1.000 71.76034  ? 230 PHE B HB2  1 
ATOM   8074 H HB3  . PHE B 1 230 ? -4.14854  -19.59932 -47.94263 1.000 71.76034  ? 230 PHE B HB3  1 
ATOM   8075 H HD1  . PHE B 1 230 ? -6.11201  -18.23124 -47.57115 1.000 63.78606  ? 230 PHE B HD1  1 
ATOM   8076 H HD2  . PHE B 1 230 ? -4.79796  -20.67445 -44.69115 1.000 55.43519  ? 230 PHE B HD2  1 
ATOM   8077 H HE1  . PHE B 1 230 ? -7.48712  -17.17737 -46.05353 1.000 59.84263  ? 230 PHE B HE1  1 
ATOM   8078 H HE2  . PHE B 1 230 ? -6.16301  -19.61236 -43.16730 1.000 68.71079  ? 230 PHE B HE2  1 
ATOM   8079 H HZ   . PHE B 1 230 ? -7.51199  -17.86169 -43.84733 1.000 67.28288  ? 230 PHE B HZ   1 
ATOM   8080 N N    . ASN B 1 231 ? -6.36932  -20.28519 -49.75748 1.000 54.42327  ? 231 ASN B N    1 
ATOM   8081 C CA   . ASN B 1 231 ? -7.59476  -19.78994 -50.37754 1.000 50.91193  ? 231 ASN B CA   1 
ATOM   8082 C C    . ASN B 1 231 ? -8.49562  -20.93412 -50.82611 1.000 55.46411  ? 231 ASN B C    1 
ATOM   8083 O O    . ASN B 1 231 ? -9.72508  -20.83329 -50.73982 1.000 57.03241  ? 231 ASN B O    1 
ATOM   8084 C CB   . ASN B 1 231 ? -7.25471  -18.88144 -51.55870 1.000 50.19338  ? 231 ASN B CB   1 
ATOM   8085 C CG   . ASN B 1 231 ? -6.81621  -17.49707 -51.12089 1.000 56.95582  ? 231 ASN B CG   1 
ATOM   8086 O OD1  . ASN B 1 231 ? -7.25018  -16.99555 -50.08343 1.000 56.32473  ? 231 ASN B OD1  1 
ATOM   8087 N ND2  . ASN B 1 231 ? -5.95267  -16.87063 -51.91261 1.000 48.92250  ? 231 ASN B ND2  1 
ATOM   8088 H H    . ASN B 1 231 ? -5.64762  -20.08146 -50.17848 1.000 65.30169  ? 231 ASN B H    1 
ATOM   8089 H HA   . ASN B 1 231 ? -8.08243  -19.26579 -49.72306 1.000 61.08809  ? 231 ASN B HA   1 
ATOM   8090 H HB2  . ASN B 1 231 ? -6.53055  -19.27971 -52.06652 1.000 60.22583  ? 231 ASN B HB2  1 
ATOM   8091 H HB3  . ASN B 1 231 ? -8.03968  -18.78470 -52.12026 1.000 60.22583  ? 231 ASN B HB3  1 
ATOM   8092 H HD21 . ASN B 1 231 ? -5.67399  -16.08337 -51.70728 1.000 58.70077  ? 231 ASN B HD21 1 
ATOM   8093 H HD22 . ASN B 1 231 ? -5.67235  -17.25237 -52.63045 1.000 58.70077  ? 231 ASN B HD22 1 
ATOM   8094 N N    . LEU B 1 232 ? -7.90742  -22.02458 -51.32359 1.000 64.76473  ? 232 LEU B N    1 
ATOM   8095 C CA   . LEU B 1 232 ? -8.70745  -23.19722 -51.66197 1.000 60.80361  ? 232 LEU B CA   1 
ATOM   8096 C C    . LEU B 1 232 ? -9.39331  -23.76563 -50.42764 1.000 60.95534  ? 232 LEU B C    1 
ATOM   8097 O O    . LEU B 1 232 ? -10.52493 -24.25518 -50.50721 1.000 72.57236  ? 232 LEU B O    1 
ATOM   8098 C CB   . LEU B 1 232 ? -7.83455  -24.26289 -52.32301 1.000 65.05380  ? 232 LEU B CB   1 
ATOM   8099 H H    . LEU B 1 232 ? -7.06426  -22.10779 -51.47109 1.000 77.71145  ? 232 LEU B H    1 
ATOM   8100 H HA   . LEU B 1 232 ? -9.39066  -22.93380 -52.29816 1.000 72.95811  ? 232 LEU B HA   1 
ATOM   8101 N N    . VAL B 1 233 ? -8.72053  -23.70998 -49.27496 1.000 58.82157  ? 233 VAL B N    1 
ATOM   8102 C CA   . VAL B 1 233 ? -9.34040  -24.14525 -48.02829 1.000 56.21976  ? 233 VAL B CA   1 
ATOM   8103 C C    . VAL B 1 233 ? -10.37539 -23.12597 -47.56858 1.000 59.17025  ? 233 VAL B C    1 
ATOM   8104 O O    . VAL B 1 233 ? -11.48946 -23.48222 -47.16724 1.000 62.70448  ? 233 VAL B O    1 
ATOM   8105 C CB   . VAL B 1 233 ? -8.26903  -24.36688 -46.94434 1.000 60.20739  ? 233 VAL B CB   1 
ATOM   8106 C CG1  . VAL B 1 233 ? -8.89791  -24.98036 -45.70133 1.000 53.80173  ? 233 VAL B CG1  1 
ATOM   8107 C CG2  . VAL B 1 233 ? -7.12737  -25.22457 -47.47019 1.000 63.20196  ? 233 VAL B CG2  1 
ATOM   8108 H H    . VAL B 1 233 ? -7.91278  -23.42690 -49.19126 1.000 70.57966  ? 233 VAL B H    1 
ATOM   8109 H HA   . VAL B 1 233 ? -9.79095  -24.98893 -48.18989 1.000 67.45748  ? 233 VAL B HA   1 
ATOM   8110 H HB   . VAL B 1 233 ? -7.88986  -23.50918 -46.69637 1.000 72.24264  ? 233 VAL B HB   1 
ATOM   8111 H HG11 . VAL B 1 233 ? -8.19326  -25.26332 -45.09776 1.000 64.55585  ? 233 VAL B HG11 1 
ATOM   8112 H HG12 . VAL B 1 233 ? -9.45650  -24.31550 -45.26908 1.000 64.55585  ? 233 VAL B HG12 1 
ATOM   8113 H HG13 . VAL B 1 233 ? -9.43539  -25.74410 -45.96348 1.000 64.55585  ? 233 VAL B HG13 1 
ATOM   8114 H HG21 . VAL B 1 233 ? -6.97789  -25.96154 -46.85748 1.000 75.83612  ? 233 VAL B HG21 1 
ATOM   8115 H HG22 . VAL B 1 233 ? -7.36636  -25.56592 -48.34613 1.000 75.83612  ? 233 VAL B HG22 1 
ATOM   8116 H HG23 . VAL B 1 233 ? -6.32707  -24.68023 -47.53437 1.000 75.83612  ? 233 VAL B HG23 1 
ATOM   8117 N N    . ALA B 1 234 ? -10.01840 -21.83949 -47.61912 1.000 60.39021  ? 234 ALA B N    1 
ATOM   8118 C CA   . ALA B 1 234 ? -10.87365 -20.80451 -47.04622 1.000 56.59857  ? 234 ALA B CA   1 
ATOM   8119 C C    . ALA B 1 234 ? -12.23511 -20.75117 -47.73092 1.000 56.78427  ? 234 ALA B C    1 
ATOM   8120 O O    . ALA B 1 234 ? -13.25540 -20.50436 -47.07689 1.000 49.40179  ? 234 ALA B O    1 
ATOM   8121 C CB   . ALA B 1 234 ? -10.17871 -19.44533 -47.13827 1.000 59.99361  ? 234 ALA B CB   1 
ATOM   8122 H H    . ALA B 1 234 ? -9.29364  -21.54461 -47.97600 1.000 72.46203  ? 234 ALA B H    1 
ATOM   8123 H HA   . ALA B 1 234 ? -11.02168 -21.01240 -46.11040 1.000 67.91206  ? 234 ALA B HA   1 
ATOM   8124 H HB1  . ALA B 1 234 ? -10.76276 -18.76618 -46.76607 1.000 71.98610  ? 234 ALA B HB1  1 
ATOM   8125 H HB2  . ALA B 1 234 ? -9.34955  -19.47993 -46.63608 1.000 71.98610  ? 234 ALA B HB2  1 
ATOM   8126 H HB3  . ALA B 1 234 ? -9.99331  -19.24787 -48.06969 1.000 71.98610  ? 234 ALA B HB3  1 
ATOM   8127 N N    . MET B 1 235 ? -12.27611 -20.97134 -49.04748 1.000 53.76431  ? 235 MET B N    1 
ATOM   8128 C CA   . MET B 1 235 ? -13.54552 -20.86722 -49.75980 1.000 55.82259  ? 235 MET B CA   1 
ATOM   8129 C C    . MET B 1 235 ? -14.51184 -21.97615 -49.36384 1.000 56.86097  ? 235 MET B C    1 
ATOM   8130 O O    . MET B 1 235 ? -15.73147 -21.79546 -49.46212 1.000 55.61061  ? 235 MET B O    1 
ATOM   8131 C CB   . MET B 1 235 ? -13.30998 -20.88846 -51.26806 1.000 52.54465  ? 235 MET B CB   1 
ATOM   8132 C CG   . MET B 1 235 ? -13.34404 -19.50772 -51.90570 1.000 75.81603  ? 235 MET B CG   1 
ATOM   8133 S SD   . MET B 1 235 ? -11.83967 -18.55226 -51.64316 1.000 83.43921  ? 235 MET B SD   1 
ATOM   8134 C CE   . MET B 1 235 ? -10.93986 -18.95773 -53.13635 1.000 72.40367  ? 235 MET B CE   1 
ATOM   8135 H H    . MET B 1 235 ? -11.59978 -21.17704 -49.53724 1.000 64.51095  ? 235 MET B H    1 
ATOM   8136 H HA   . MET B 1 235 ? -13.94648 -20.01303 -49.53508 1.000 66.98088  ? 235 MET B HA   1 
ATOM   8137 H HB2  . MET B 1 235 ? -12.43798 -21.27554 -51.44322 1.000 63.04736  ? 235 MET B HB2  1 
ATOM   8138 H HB3  . MET B 1 235 ? -14.00139 -21.42588 -51.68525 1.000 63.04736  ? 235 MET B HB3  1 
ATOM   8139 H HG2  . MET B 1 235 ? -13.46764 -19.60833 -52.86252 1.000 90.97301  ? 235 MET B HG2  1 
ATOM   8140 H HG3  . MET B 1 235 ? -14.08298 -19.00657 -51.52662 1.000 90.97301  ? 235 MET B HG3  1 
ATOM   8141 H HE1  . MET B 1 235 ? -10.05141 -18.57192 -53.08427 1.000 86.87818  ? 235 MET B HE1  1 
ATOM   8142 H HE2  . MET B 1 235 ? -10.87742 -19.92249 -53.21529 1.000 86.87818  ? 235 MET B HE2  1 
ATOM   8143 H HE3  . MET B 1 235 ? -11.41446 -18.59339 -53.89983 1.000 86.87818  ? 235 MET B HE3  1 
ATOM   8144 N N    . LYS B 1 236 ? -13.99569 -23.12501 -48.92137 1.000 49.08996  ? 236 LYS B N    1 
ATOM   8145 C CA   . LYS B 1 236 ? -14.87683 -24.18673 -48.44975 1.000 50.49084  ? 236 LYS B CA   1 
ATOM   8146 C C    . LYS B 1 236 ? -15.68289 -23.73911 -47.23734 1.000 48.82413  ? 236 LYS B C    1 
ATOM   8147 O O    . LYS B 1 236 ? -16.82210 -24.18298 -47.05019 1.000 47.02815  ? 236 LYS B O    1 
ATOM   8148 C CB   . LYS B 1 236 ? -14.05897 -25.43387 -48.11408 1.000 52.22932  ? 236 LYS B CB   1 
ATOM   8149 H H    . LYS B 1 236 ? -13.15635 -23.30892 -48.88548 1.000 58.90173  ? 236 LYS B H    1 
ATOM   8150 H HA   . LYS B 1 236 ? -15.49898 -24.41856 -49.15691 1.000 60.58278  ? 236 LYS B HA   1 
ATOM   8151 N N    . TYR B 1 237 ? -15.11973 -22.85010 -46.41806 1.000 46.78958  ? 237 TYR B N    1 
ATOM   8152 C CA   . TYR B 1 237 ? -15.75291 -22.39160 -45.18911 1.000 54.22562  ? 237 TYR B CA   1 
ATOM   8153 C C    . TYR B 1 237 ? -16.39667 -21.01826 -45.32620 1.000 46.71065  ? 237 TYR B C    1 
ATOM   8154 O O    . TYR B 1 237 ? -16.74992 -20.40801 -44.31267 1.000 48.13037  ? 237 TYR B O    1 
ATOM   8155 C CB   . TYR B 1 237 ? -14.72967 -22.37102 -44.05319 1.000 43.84586  ? 237 TYR B CB   1 
ATOM   8156 C CG   . TYR B 1 237 ? -14.17029 -23.73400 -43.75059 1.000 49.22645  ? 237 TYR B CG   1 
ATOM   8157 C CD1  . TYR B 1 237 ? -13.06529 -24.21520 -44.43565 1.000 56.42803  ? 237 TYR B CD1  1 
ATOM   8158 C CD2  . TYR B 1 237 ? -14.75695 -24.54837 -42.79217 1.000 44.38836  ? 237 TYR B CD2  1 
ATOM   8159 C CE1  . TYR B 1 237 ? -12.55363 -25.46544 -44.17035 1.000 61.83640  ? 237 TYR B CE1  1 
ATOM   8160 C CE2  . TYR B 1 237 ? -14.25255 -25.79901 -42.51723 1.000 50.08689  ? 237 TYR B CE2  1 
ATOM   8161 C CZ   . TYR B 1 237 ? -13.15154 -26.25472 -43.21057 1.000 64.90907  ? 237 TYR B CZ   1 
ATOM   8162 O OH   . TYR B 1 237 ? -12.64507 -27.50468 -42.94154 1.000 65.76891  ? 237 TYR B OH   1 
ATOM   8163 H H    . TYR B 1 237 ? -14.35120 -22.49098 -46.55948 1.000 56.14127  ? 237 TYR B H    1 
ATOM   8164 H HA   . TYR B 1 237 ? -16.45438 -23.02015 -44.95724 1.000 65.06451  ? 237 TYR B HA   1 
ATOM   8165 H HB2  . TYR B 1 237 ? -13.99236 -21.79220 -44.30268 1.000 52.60881  ? 237 TYR B HB2  1 
ATOM   8166 H HB3  . TYR B 1 237 ? -15.15689 -22.03626 -43.24925 1.000 52.60881  ? 237 TYR B HB3  1 
ATOM   8167 H HD1  . TYR B 1 237 ? -12.66307 -23.68475 -45.08506 1.000 67.70741  ? 237 TYR B HD1  1 
ATOM   8168 H HD2  . TYR B 1 237 ? -15.50319 -24.24400 -42.32807 1.000 53.25981  ? 237 TYR B HD2  1 
ATOM   8169 H HE1  . TYR B 1 237 ? -11.81012 -25.77549 -44.63507 1.000 74.19745  ? 237 TYR B HE1  1 
ATOM   8170 H HE2  . TYR B 1 237 ? -14.65149 -26.33278 -41.86851 1.000 60.09804  ? 237 TYR B HE2  1 
ATOM   8171 H HH   . TYR B 1 237 ? -13.13856 -27.90202 -42.39002 1.000 78.91646  ? 237 TYR B HH   1 
ATOM   8172 N N    . ASN B 1 238 ? -16.55721 -20.51803 -46.54982 1.000 55.16257  ? 238 ASN B N    1 
ATOM   8173 C CA   . ASN B 1 238 ? -17.21639 -19.23529 -46.78669 1.000 49.22411  ? 238 ASN B CA   1 
ATOM   8174 C C    . ASN B 1 238 ? -16.37870 -18.07243 -46.25450 1.000 49.53929  ? 238 ASN B C    1 
ATOM   8175 O O    . ASN B 1 238 ? -16.90846 -17.09222 -45.72920 1.000 49.20287  ? 238 ASN B O    1 
ATOM   8176 C CB   . ASN B 1 238 ? -18.61709 -19.22544 -46.17424 1.000 46.52056  ? 238 ASN B CB   1 
ATOM   8177 C CG   . ASN B 1 238 ? -19.51897 -18.20529 -46.81504 1.000 50.50073  ? 238 ASN B CG   1 
ATOM   8178 O OD1  . ASN B 1 238 ? -20.10098 -17.36646 -46.13404 1.000 67.21756  ? 238 ASN B OD1  1 
ATOM   8179 N ND2  . ASN B 1 238 ? -19.63357 -18.26250 -48.13763 1.000 57.28788  ? 238 ASN B ND2  1 
ATOM   8180 H H    . ASN B 1 238 ? -16.28945 -20.90787 -47.26810 1.000 66.18886  ? 238 ASN B H    1 
ATOM   8181 H HA   . ASN B 1 238 ? -17.30549 -19.10250 -47.74341 1.000 59.06270  ? 238 ASN B HA   1 
ATOM   8182 H HB2  . ASN B 1 238 ? -19.02053 -20.09973 -46.29148 1.000 55.81845  ? 238 ASN B HB2  1 
ATOM   8183 H HB3  . ASN B 1 238 ? -18.54865 -19.01560 -45.22969 1.000 55.81845  ? 238 ASN B HB3  1 
ATOM   8184 H HD21 . ASN B 1 238 ? -20.13740 -17.70082 -48.55028 1.000 68.73923  ? 238 ASN B HD21 1 
ATOM   8185 H HD22 . ASN B 1 238 ? -19.20391 -18.86119 -48.58097 1.000 68.73923  ? 238 ASN B HD22 1 
ATOM   8186 N N    . TYR B 1 239 ? -15.06227 -18.18923 -46.39043 1.000 45.33356  ? 239 TYR B N    1 
ATOM   8187 C CA   . TYR B 1 239 ? -14.12896 -17.11751 -46.07694 1.000 43.27515  ? 239 TYR B CA   1 
ATOM   8188 C C    . TYR B 1 239 ? -13.73962 -16.40786 -47.36650 1.000 44.38745  ? 239 TYR B C    1 
ATOM   8189 O O    . TYR B 1 239 ? -13.40380 -17.06196 -48.36002 1.000 44.64377  ? 239 TYR B O    1 
ATOM   8190 C CB   . TYR B 1 239 ? -12.88136 -17.66980 -45.38714 1.000 39.99033  ? 239 TYR B CB   1 
ATOM   8191 C CG   . TYR B 1 239 ? -12.97208 -17.70968 -43.88498 1.000 40.52803  ? 239 TYR B CG   1 
ATOM   8192 C CD1  . TYR B 1 239 ? -13.97920 -18.41776 -43.25080 1.000 36.54342  ? 239 TYR B CD1  1 
ATOM   8193 C CD2  . TYR B 1 239 ? -12.03760 -17.05016 -43.09891 1.000 38.50256  ? 239 TYR B CD2  1 
ATOM   8194 C CE1  . TYR B 1 239 ? -14.06168 -18.45899 -41.87563 1.000 38.69519  ? 239 TYR B CE1  1 
ATOM   8195 C CE2  . TYR B 1 239 ? -12.11195 -17.08488 -41.72352 1.000 38.98719  ? 239 TYR B CE2  1 
ATOM   8196 C CZ   . TYR B 1 239 ? -13.12630 -17.78785 -41.11618 1.000 37.72261  ? 239 TYR B CZ   1 
ATOM   8197 O OH   . TYR B 1 239 ? -13.19957 -17.82246 -39.74290 1.000 41.30030  ? 239 TYR B OH   1 
ATOM   8198 H H    . TYR B 1 239 ? -14.67475 -18.90355 -46.67182 1.000 54.39404  ? 239 TYR B H    1 
ATOM   8199 H HA   . TYR B 1 239 ? -14.54954 -16.47861 -45.48043 1.000 51.92396  ? 239 TYR B HA   1 
ATOM   8200 H HB2  . TYR B 1 239 ? -12.73181 -18.57678 -45.69683 1.000 47.98216  ? 239 TYR B HB2  1 
ATOM   8201 H HB3  . TYR B 1 239 ? -12.12439 -17.11024 -45.62122 1.000 47.98216  ? 239 TYR B HB3  1 
ATOM   8202 H HD1  . TYR B 1 239 ? -14.60987 -18.87266 -43.76092 1.000 43.84588  ? 239 TYR B HD1  1 
ATOM   8203 H HD2  . TYR B 1 239 ? -11.34936 -16.57662 -43.50755 1.000 46.19684  ? 239 TYR B HD2  1 
ATOM   8204 H HE1  . TYR B 1 239 ? -14.74418 -18.93665 -41.46218 1.000 46.42799  ? 239 TYR B HE1  1 
ATOM   8205 H HE2  . TYR B 1 239 ? -11.48043 -16.63595 -41.20918 1.000 46.77840  ? 239 TYR B HE2  1 
ATOM   8206 H HH   . TYR B 1 239 ? -13.82865 -18.32395 -39.50131 1.000 49.55413  ? 239 TYR B HH   1 
ATOM   8207 N N    . GLU B 1 240 ? -13.79619 -15.08133 -47.35378 1.000 49.96656  ? 240 GLU B N    1 
ATOM   8208 C CA   . GLU B 1 240 ? -13.33628 -14.31769 -48.50379 1.000 47.93167  ? 240 GLU B CA   1 
ATOM   8209 C C    . GLU B 1 240 ? -11.90801 -14.72903 -48.85433 1.000 44.28639  ? 240 GLU B C    1 
ATOM   8210 O O    . GLU B 1 240 ? -11.09075 -14.95866 -47.95227 1.000 45.63139  ? 240 GLU B O    1 
ATOM   8211 C CB   . GLU B 1 240 ? -13.39567 -12.81546 -48.20998 1.000 47.58585  ? 240 GLU B CB   1 
ATOM   8212 C CG   . GLU B 1 240 ? -14.79991 -12.22268 -48.25920 1.000 58.95096  ? 240 GLU B CG   1 
ATOM   8213 C CD   . GLU B 1 240 ? -15.36006 -12.14891 -49.67042 1.000 63.73507  ? 240 GLU B CD   1 
ATOM   8214 O OE1  . GLU B 1 240 ? -14.56994 -11.95137 -50.61685 1.000 78.99029  ? 240 GLU B OE1  1 
ATOM   8215 O OE2  . GLU B 1 240 ? -16.59051 -12.29115 -49.83619 1.000 60.00107  ? 240 GLU B OE2  1 
ATOM   8216 H H    . GLU B 1 240 ? -14.09232 -14.60634 -46.70088 1.000 59.95364  ? 240 GLU B H    1 
ATOM   8217 H HA   . GLU B 1 240 ? -13.90969 -14.49761 -49.26519 1.000 57.51178  ? 240 GLU B HA   1 
ATOM   8218 H HB2  . GLU B 1 240 ? -13.04165 -12.65944 -47.32047 1.000 57.09680  ? 240 GLU B HB2  1 
ATOM   8219 H HB3  . GLU B 1 240 ? -12.85655 -12.34944 -48.86807 1.000 57.09680  ? 240 GLU B HB3  1 
ATOM   8220 H HG2  . GLU B 1 240 ? -15.39493 -12.77582 -47.72922 1.000 70.73493  ? 240 GLU B HG2  1 
ATOM   8221 H HG3  . GLU B 1 240 ? -14.77539 -11.32230 -47.89916 1.000 70.73493  ? 240 GLU B HG3  1 
ATOM   8222 N N    . PRO B 1 241 ? -11.56724 -14.84191 -50.13754 1.000 43.89924  ? 241 PRO B N    1 
ATOM   8223 C CA   . PRO B 1 241 ? -10.19175 -15.19879 -50.49870 1.000 52.61331  ? 241 PRO B CA   1 
ATOM   8224 C C    . PRO B 1 241 ? -9.20077  -14.12469 -50.07791 1.000 44.68005  ? 241 PRO B C    1 
ATOM   8225 O O    . PRO B 1 241 ? -9.50934  -12.93191 -50.05261 1.000 47.55188  ? 241 PRO B O    1 
ATOM   8226 C CB   . PRO B 1 241 ? -10.24827 -15.34144 -52.02464 1.000 56.37642  ? 241 PRO B CB   1 
ATOM   8227 C CG   . PRO B 1 241 ? -11.41699 -14.51476 -52.43552 1.000 44.39586  ? 241 PRO B CG   1 
ATOM   8228 C CD   . PRO B 1 241 ? -12.41852 -14.67843 -51.32920 1.000 56.17277  ? 241 PRO B CD   1 
ATOM   8229 H HA   . PRO B 1 241 ? -9.94232  -16.04551 -50.09652 1.000 63.12975  ? 241 PRO B HA   1 
ATOM   8230 H HB2  . PRO B 1 241 ? -9.42816  -15.00655 -52.41983 1.000 67.64547  ? 241 PRO B HB2  1 
ATOM   8231 H HB3  . PRO B 1 241 ? -10.37717 -16.27195 -52.26639 1.000 67.64547  ? 241 PRO B HB3  1 
ATOM   8232 H HG2  . PRO B 1 241 ? -11.14968 -13.58676 -52.52639 1.000 53.26880  ? 241 PRO B HG2  1 
ATOM   8233 H HG3  . PRO B 1 241 ? -11.77331 -14.84125 -53.27655 1.000 53.26880  ? 241 PRO B HG3  1 
ATOM   8234 H HD2  . PRO B 1 241 ? -12.97919 -13.89090 -51.24956 1.000 67.40110  ? 241 PRO B HD2  1 
ATOM   8235 H HD3  . PRO B 1 241 ? -12.96874 -15.46426 -51.47287 1.000 67.40110  ? 241 PRO B HD3  1 
ATOM   8236 N N    . LEU B 1 242 ? -7.99370  -14.56845 -49.74892 1.000 50.09433  ? 242 LEU B N    1 
ATOM   8237 C CA   . LEU B 1 242 ? -6.92123  -13.69370 -49.29591 1.000 48.44101  ? 242 LEU B CA   1 
ATOM   8238 C C    . LEU B 1 242 ? -6.04064  -13.34514 -50.49038 1.000 53.69347  ? 242 LEU B C    1 
ATOM   8239 O O    . LEU B 1 242 ? -5.53578  -14.24151 -51.17585 1.000 57.47072  ? 242 LEU B O    1 
ATOM   8240 C CB   . LEU B 1 242 ? -6.11036  -14.37938 -48.19796 1.000 42.14025  ? 242 LEU B CB   1 
ATOM   8241 C CG   . LEU B 1 242 ? -5.26993  -13.51235 -47.26408 1.000 48.98634  ? 242 LEU B CG   1 
ATOM   8242 C CD1  . LEU B 1 242 ? -6.15247  -12.69364 -46.32912 1.000 49.46802  ? 242 LEU B CD1  1 
ATOM   8243 C CD2  . LEU B 1 242 ? -4.32105  -14.40371 -46.47701 1.000 48.19153  ? 242 LEU B CD2  1 
ATOM   8244 H H    . LEU B 1 242 ? -7.76563  -15.39703 -49.78108 1.000 60.10697  ? 242 LEU B H    1 
ATOM   8245 H HA   . LEU B 1 242 ? -7.28633  -12.86975 -48.93714 1.000 58.12298  ? 242 LEU B HA   1 
ATOM   8246 H HB2  . LEU B 1 242 ? -6.73256  -14.86769 -47.63642 1.000 50.56207  ? 242 LEU B HB2  1 
ATOM   8247 H HB3  . LEU B 1 242 ? -5.49777  -14.99604 -48.62850 1.000 50.56207  ? 242 LEU B HB3  1 
ATOM   8248 H HG   . LEU B 1 242 ? -4.75046  -12.88002 -47.78487 1.000 58.77738  ? 242 LEU B HG   1 
ATOM   8249 H HD11 . LEU B 1 242 ? -6.64119  -13.29675 -45.74748 1.000 59.35539  ? 242 LEU B HD11 1 
ATOM   8250 H HD12 . LEU B 1 242 ? -5.59144  -12.10561 -45.79962 1.000 59.35539  ? 242 LEU B HD12 1 
ATOM   8251 H HD13 . LEU B 1 242 ? -6.77332  -12.16969 -46.85914 1.000 59.35539  ? 242 LEU B HD13 1 
ATOM   8252 H HD21 . LEU B 1 242 ? -3.72332  -14.85238 -47.09533 1.000 57.82361  ? 242 LEU B HD21 1 
ATOM   8253 H HD22 . LEU B 1 242 ? -3.80967  -13.85512 -45.86183 1.000 57.82361  ? 242 LEU B HD22 1 
ATOM   8254 H HD23 . LEU B 1 242 ? -4.83922  -15.05873 -45.98371 1.000 57.82361  ? 242 LEU B HD23 1 
ATOM   8255 N N    . THR B 1 243 ? -5.86872  -12.05096 -50.74299 1.000 42.40105  ? 243 THR B N    1 
ATOM   8256 C CA   . THR B 1 243 ? -5.06383  -11.56998 -51.85520 1.000 41.17920  ? 243 THR B CA   1 
ATOM   8257 C C    . THR B 1 243 ? -3.67731  -11.16425 -51.36353 1.000 50.94543  ? 243 THR B C    1 
ATOM   8258 O O    . THR B 1 243 ? -3.41662  -11.06543 -50.16165 1.000 43.88494  ? 243 THR B O    1 
ATOM   8259 C CB   . THR B 1 243 ? -5.74087  -10.37996 -52.55067 1.000 52.75629  ? 243 THR B CB   1 
ATOM   8260 O OG1  . THR B 1 243 ? -5.68323  -9.22427  -51.70245 1.000 50.25187  ? 243 THR B OG1  1 
ATOM   8261 C CG2  . THR B 1 243 ? -7.20327  -10.68860 -52.88121 1.000 46.48065  ? 243 THR B CG2  1 
ATOM   8262 H H    . THR B 1 243 ? -6.21679  -11.42073 -50.27262 1.000 50.87503  ? 243 THR B H    1 
ATOM   8263 H HA   . THR B 1 243 ? -4.97098  -12.28432 -52.50482 1.000 49.40882  ? 243 THR B HA   1 
ATOM   8264 H HB   . THR B 1 243 ? -5.27614  -10.19847 -53.38253 1.000 63.30132  ? 243 THR B HB   1 
ATOM   8265 H HG1  . THR B 1 243 ? -6.12223  -8.59490  -52.04417 1.000 60.29602  ? 243 THR B HG1  1 
ATOM   8266 H HG21 . THR B 1 243 ? -7.25243  -11.41692 -53.51999 1.000 55.77056  ? 243 THR B HG21 1 
ATOM   8267 H HG22 . THR B 1 243 ? -7.67877  -10.94409 -52.07529 1.000 55.77056  ? 243 THR B HG22 1 
ATOM   8268 H HG23 . THR B 1 243 ? -7.62945  -9.90547  -53.26328 1.000 55.77056  ? 243 THR B HG23 1 
ATOM   8269 N N    . GLN B 1 244 ? -2.77775  -10.92535 -52.32175 1.000 52.63435  ? 244 GLN B N    1 
ATOM   8270 C CA   . GLN B 1 244 ? -1.45823  -10.41059 -51.97256 1.000 45.17826  ? 244 GLN B CA   1 
ATOM   8271 C C    . GLN B 1 244 ? -1.55622  -9.02620  -51.34606 1.000 53.99168  ? 244 GLN B C    1 
ATOM   8272 O O    . GLN B 1 244 ? -0.74236  -8.67401  -50.48307 1.000 46.23447  ? 244 GLN B O    1 
ATOM   8273 C CB   . GLN B 1 244 ? -0.56112  -10.36758 -53.20991 1.000 49.94501  ? 244 GLN B CB   1 
ATOM   8274 C CG   . GLN B 1 244 ? 0.83605   -9.82020  -52.94495 1.000 44.07620  ? 244 GLN B CG   1 
ATOM   8275 C CD   . GLN B 1 244 ? 1.63182   -10.68332 -51.98322 1.000 45.62081  ? 244 GLN B CD   1 
ATOM   8276 O OE1  . GLN B 1 244 ? 1.62558   -11.91129 -52.08299 1.000 40.42987  ? 244 GLN B OE1  1 
ATOM   8277 N NE2  . GLN B 1 244 ? 2.31852   -10.04292 -51.03958 1.000 48.95314  ? 244 GLN B NE2  1 
ATOM   8278 H H    . GLN B 1 244 ? -2.90586  -11.05091 -53.16283 1.000 63.15500  ? 244 GLN B H    1 
ATOM   8279 H HA   . GLN B 1 244 ? -1.04834  -11.01022 -51.32965 1.000 54.20768  ? 244 GLN B HA   1 
ATOM   8280 H HB2  . GLN B 1 244 ? -0.46421  -11.26897 -53.55488 1.000 59.92779  ? 244 GLN B HB2  1 
ATOM   8281 H HB3  . GLN B 1 244 ? -0.97859  -9.80023  -53.87678 1.000 59.92779  ? 244 GLN B HB3  1 
ATOM   8282 H HG2  . GLN B 1 244 ? 1.32296   -9.77741  -53.78279 1.000 52.88521  ? 244 GLN B HG2  1 
ATOM   8283 H HG3  . GLN B 1 244 ? 0.76027   -8.93326  -52.55960 1.000 52.88521  ? 244 GLN B HG3  1 
ATOM   8284 H HE21 . GLN B 1 244 ? 2.29546   -9.18419  -50.99897 1.000 58.73754  ? 244 GLN B HE21 1 
ATOM   8285 H HE22 . GLN B 1 244 ? 2.78519   -10.48793 -50.47056 1.000 58.73754  ? 244 GLN B HE22 1 
ATOM   8286 N N    . ASP B 1 245 ? -2.53678  -8.22528  -51.77034 1.000 51.69846  ? 245 ASP B N    1 
ATOM   8287 C CA   . ASP B 1 245 ? -2.73998  -6.92278  -51.14587 1.000 52.50345  ? 245 ASP B CA   1 
ATOM   8288 C C    . ASP B 1 245 ? -3.11502  -7.07444  -49.67637 1.000 50.63597  ? 245 ASP B C    1 
ATOM   8289 O O    . ASP B 1 245 ? -2.64262  -6.31018  -48.82686 1.000 45.34995  ? 245 ASP B O    1 
ATOM   8290 C CB   . ASP B 1 245 ? -3.81285  -6.13914  -51.90163 1.000 51.28539  ? 245 ASP B CB   1 
ATOM   8291 C CG   . ASP B 1 245 ? -3.33224  -5.65232  -53.25696 1.000 53.43632  ? 245 ASP B CG   1 
ATOM   8292 O OD1  . ASP B 1 245 ? -2.17544  -5.94719  -53.62228 1.000 65.38505  ? 245 ASP B OD1  1 
ATOM   8293 O OD2  . ASP B 1 245 ? -4.10777  -4.97092  -53.95722 1.000 54.93505  ? 245 ASP B OD2  1 
ATOM   8294 H H    . ASP B 1 245 ? -3.08620  -8.41054  -52.40549 1.000 62.03193  ? 245 ASP B H    1 
ATOM   8295 H HA   . ASP B 1 245 ? -1.91399  -6.41657  -51.19487 1.000 62.99791  ? 245 ASP B HA   1 
ATOM   8296 H HB2  . ASP B 1 245 ? -4.58274  -6.71190  -52.04344 1.000 61.53624  ? 245 ASP B HB2  1 
ATOM   8297 H HB3  . ASP B 1 245 ? -4.06798  -5.36427  -51.37685 1.000 61.53624  ? 245 ASP B HB3  1 
ATOM   8298 N N    . HIS B 1 246 ? -3.96654  -8.05554  -49.35711 1.000 41.56037  ? 246 HIS B N    1 
ATOM   8299 C CA   . HIS B 1 246 ? -4.26062  -8.35436  -47.95806 1.000 43.87344  ? 246 HIS B CA   1 
ATOM   8300 C C    . HIS B 1 246 ? -2.99515  -8.75439  -47.20902 1.000 44.57068  ? 246 HIS B C    1 
ATOM   8301 O O    . HIS B 1 246 ? -2.80687  -8.38430  -46.04433 1.000 38.98494  ? 246 HIS B O    1 
ATOM   8302 C CB   . HIS B 1 246 ? -5.30470  -9.46840  -47.86268 1.000 37.83789  ? 246 HIS B CB   1 
ATOM   8303 C CG   . HIS B 1 246 ? -6.64387  -9.09753  -48.42080 1.000 45.95630  ? 246 HIS B CG   1 
ATOM   8304 N ND1  . HIS B 1 246 ? -7.54173  -10.03611 -48.88207 1.000 43.58968  ? 246 HIS B ND1  1 
ATOM   8305 C CD2  . HIS B 1 246 ? -7.24223  -7.89364  -48.58299 1.000 38.36208  ? 246 HIS B CD2  1 
ATOM   8306 C CE1  . HIS B 1 246 ? -8.63264  -9.42656  -49.31014 1.000 40.46887  ? 246 HIS B CE1  1 
ATOM   8307 N NE2  . HIS B 1 246 ? -8.47709  -8.12609  -49.13907 1.000 43.21270  ? 246 HIS B NE2  1 
ATOM   8308 H H    . HIS B 1 246 ? -4.37924  -8.55344  -49.92402 1.000 49.86621  ? 246 HIS B H    1 
ATOM   8309 H HA   . HIS B 1 246 ? -4.62878  -7.55998  -47.54055 1.000 52.64190  ? 246 HIS B HA   1 
ATOM   8310 H HB2  . HIS B 1 246 ? -4.98282  -10.23925 -48.35571 1.000 45.39924  ? 246 HIS B HB2  1 
ATOM   8311 H HB3  . HIS B 1 246 ? -5.42810  -9.69977  -46.92880 1.000 45.39924  ? 246 HIS B HB3  1 
ATOM   8312 H HD2  . HIS B 1 246 ? -6.88442  -7.06474  -48.35981 1.000 46.02826  ? 246 HIS B HD2  1 
ATOM   8313 H HE1  . HIS B 1 246 ? -9.38245  -9.84223  -49.67056 1.000 48.55641  ? 246 HIS B HE1  1 
ATOM   8314 H HE2  . HIS B 1 246 ? -9.05501  -7.52265  -49.34272 1.000 51.84901  ? 246 HIS B HE2  1 
ATOM   8315 N N    . VAL B 1 247 ? -2.11544  -9.51223  -47.86451 1.000 46.17160  ? 247 VAL B N    1 
ATOM   8316 C CA   . VAL B 1 247 ? -0.85563  -9.90056  -47.24008 1.000 45.13803  ? 247 VAL B CA   1 
ATOM   8317 C C    . VAL B 1 247 ? 0.00828   -8.67376  -46.97463 1.000 41.51853  ? 247 VAL B C    1 
ATOM   8318 O O    . VAL B 1 247 ? 0.71954   -8.60524  -45.96557 1.000 42.11033  ? 247 VAL B O    1 
ATOM   8319 C CB   . VAL B 1 247 ? -0.13089  -10.93376 -48.12299 1.000 42.14872  ? 247 VAL B CB   1 
ATOM   8320 C CG1  . VAL B 1 247 ? 1.32383   -11.07905 -47.69945 1.000 34.38839  ? 247 VAL B CG1  1 
ATOM   8321 C CG2  . VAL B 1 247 ? -0.85596  -12.27217 -48.05810 1.000 39.74262  ? 247 VAL B CG2  1 
ATOM   8322 H H    . VAL B 1 247 ? -2.22397  -9.81109  -48.66358 1.000 55.39969  ? 247 VAL B H    1 
ATOM   8323 H HA   . VAL B 1 247 ? -1.04415  -10.31556 -46.38384 1.000 54.15941  ? 247 VAL B HA   1 
ATOM   8324 H HB   . VAL B 1 247 ? -0.13714  -10.62777 -49.04344 1.000 50.57223  ? 247 VAL B HB   1 
ATOM   8325 H HG11 . VAL B 1 247 ? 1.40254   -10.85660 -46.75859 1.000 41.25984  ? 247 VAL B HG11 1 
ATOM   8326 H HG12 . VAL B 1 247 ? 1.60583   -11.99528 -47.84744 1.000 41.25984  ? 247 VAL B HG12 1 
ATOM   8327 H HG13 . VAL B 1 247 ? 1.86860   -10.47570 -48.22870 1.000 41.25984  ? 247 VAL B HG13 1 
ATOM   8328 H HG21 . VAL B 1 247 ? -1.76845  -12.12310 -47.76477 1.000 47.68491  ? 247 VAL B HG21 1 
ATOM   8329 H HG22 . VAL B 1 247 ? -0.85381  -12.67559 -48.94022 1.000 47.68491  ? 247 VAL B HG22 1 
ATOM   8330 H HG23 . VAL B 1 247 ? -0.39649  -12.85007 -47.42896 1.000 47.68491  ? 247 VAL B HG23 1 
ATOM   8331 N N    . ASP B 1 248 ? -0.03818  -7.68541  -47.87049 1.000 41.36370  ? 248 ASP B N    1 
ATOM   8332 C CA   . ASP B 1 248 ? 0.74805   -6.47364  -47.66317 1.000 41.56028  ? 248 ASP B CA   1 
ATOM   8333 C C    . ASP B 1 248 ? 0.15255   -5.59898  -46.56620 1.000 43.17820  ? 248 ASP B C    1 
ATOM   8334 O O    . ASP B 1 248 ? 0.89558   -4.93576  -45.83315 1.000 36.75616  ? 248 ASP B O    1 
ATOM   8335 C CB   . ASP B 1 248 ? 0.85339   -5.68879  -48.97031 1.000 45.02981  ? 248 ASP B CB   1 
ATOM   8336 C CG   . ASP B 1 248 ? 1.64517   -6.42934  -50.03607 1.000 51.45258  ? 248 ASP B CG   1 
ATOM   8337 O OD1  . ASP B 1 248 ? 2.26609   -7.46547  -49.71266 1.000 46.48335  ? 248 ASP B OD1  1 
ATOM   8338 O OD2  . ASP B 1 248 ? 1.64509   -5.97205  -51.19935 1.000 49.81586  ? 248 ASP B OD2  1 
ATOM   8339 H H    . ASP B 1 248 ? -0.50754  -7.69285  -48.59108 1.000 49.63021  ? 248 ASP B H    1 
ATOM   8340 H HA   . ASP B 1 248 ? 1.64450   -6.72517  -47.39112 1.000 49.86611  ? 248 ASP B HA   1 
ATOM   8341 H HB2  . ASP B 1 248 ? -0.03865  -5.52855  -49.31597 1.000 54.02954  ? 248 ASP B HB2  1 
ATOM   8342 H HB3  . ASP B 1 248 ? 1.29884   -4.84462  -48.79754 1.000 54.02954  ? 248 ASP B HB3  1 
ATOM   8343 N N    . ILE B 1 249 ? -1.17763  -5.57943  -46.44325 1.000 44.43124  ? 249 ILE B N    1 
ATOM   8344 C CA   . ILE B 1 249 ? -1.82339  -4.83657  -45.36290 1.000 44.93172  ? 249 ILE B CA   1 
ATOM   8345 C C    . ILE B 1 249 ? -1.43219  -5.41964  -44.01021 1.000 33.71967  ? 249 ILE B C    1 
ATOM   8346 O O    . ILE B 1 249 ? -1.19587  -4.68366  -43.04475 1.000 36.53728  ? 249 ILE B O    1 
ATOM   8347 C CB   . ILE B 1 249 ? -3.35279  -4.83837  -45.56036 1.000 48.40895  ? 249 ILE B CB   1 
ATOM   8348 C CG1  . ILE B 1 249 ? -3.73191  -4.05979  -46.82330 1.000 49.27015  ? 249 ILE B CG1  1 
ATOM   8349 C CG2  . ILE B 1 249 ? -4.06793  -4.23495  -44.35558 1.000 50.04503  ? 249 ILE B CG2  1 
ATOM   8350 C CD1  . ILE B 1 249 ? -5.21502  -4.11532  -47.15939 1.000 56.18818  ? 249 ILE B CD1  1 
ATOM   8351 H H    . ILE B 1 249 ? -1.72387  -5.98543  -46.96898 1.000 53.31126  ? 249 ILE B H    1 
ATOM   8352 H HA   . ILE B 1 249 ? -1.51637  -3.91686  -45.39093 1.000 53.91184  ? 249 ILE B HA   1 
ATOM   8353 H HB   . ILE B 1 249 ? -3.63083  -5.76273  -45.65603 1.000 58.08452  ? 249 ILE B HB   1 
ATOM   8354 H HG12 . ILE B 1 249 ? -3.49184  -3.12827  -46.69866 1.000 59.11795  ? 249 ILE B HG12 1 
ATOM   8355 H HG13 . ILE B 1 249 ? -3.24436  -4.43024  -47.57560 1.000 59.11795  ? 249 ILE B HG13 1 
ATOM   8356 H HG21 . ILE B 1 249 ? -3.81057  -4.72365  -43.55819 1.000 60.04781  ? 249 ILE B HG21 1 
ATOM   8357 H HG22 . ILE B 1 249 ? -3.81125  -3.30346  -44.26991 1.000 60.04781  ? 249 ILE B HG22 1 
ATOM   8358 H HG23 . ILE B 1 249 ? -5.02610  -4.30297  -44.49041 1.000 60.04781  ? 249 ILE B HG23 1 
ATOM   8359 H HD11 . ILE B 1 249 ? -5.67677  -3.41892  -46.66672 1.000 67.41958  ? 249 ILE B HD11 1 
ATOM   8360 H HD12 . ILE B 1 249 ? -5.32820  -3.97665  -48.11273 1.000 67.41958  ? 249 ILE B HD12 1 
ATOM   8361 H HD13 . ILE B 1 249 ? -5.56346  -4.98496  -46.90796 1.000 67.41958  ? 249 ILE B HD13 1 
ATOM   8362 N N    . LEU B 1 250 ? -1.36672  -6.74851  -43.91604 1.000 35.56864  ? 250 LEU B N    1 
ATOM   8363 C CA   . LEU B 1 250 ? -1.02768  -7.43222  -42.67229 1.000 38.16210  ? 250 LEU B CA   1 
ATOM   8364 C C    . LEU B 1 250 ? 0.44920   -7.32135  -42.29872 1.000 44.10623  ? 250 LEU B C    1 
ATOM   8365 O O    . LEU B 1 250 ? 0.83622   -7.84413  -41.24663 1.000 37.67327  ? 250 LEU B O    1 
ATOM   8366 C CB   . LEU B 1 250 ? -1.41196  -8.91062  -42.78061 1.000 34.75464  ? 250 LEU B CB   1 
ATOM   8367 C CG   . LEU B 1 250 ? -2.90191  -9.24788  -42.67893 1.000 40.13026  ? 250 LEU B CG   1 
ATOM   8368 C CD1  . LEU B 1 250 ? -3.16335  -10.67739 -43.13255 1.000 32.41044  ? 250 LEU B CD1  1 
ATOM   8369 C CD2  . LEU B 1 250 ? -3.41224  -9.02986  -41.25381 1.000 33.84756  ? 250 LEU B CD2  1 
ATOM   8370 H H    . LEU B 1 250 ? -1.51740  -7.28475  -44.57128 1.000 42.67614  ? 250 LEU B H    1 
ATOM   8371 H HA   . LEU B 1 250 ? -1.53987  -7.02785  -41.95461 1.000 45.78829  ? 250 LEU B HA   1 
ATOM   8372 H HB2  . LEU B 1 250 ? -1.10567  -9.23679  -43.64125 1.000 41.69934  ? 250 LEU B HB2  1 
ATOM   8373 H HB3  . LEU B 1 250 ? -0.96367  -9.38913  -42.06580 1.000 41.69934  ? 250 LEU B HB3  1 
ATOM   8374 H HG   . LEU B 1 250 ? -3.39617  -8.65403  -43.26540 1.000 48.15008  ? 250 LEU B HG   1 
ATOM   8375 H HD11 . LEU B 1 250 ? -4.07912  -10.91436 -42.91783 1.000 38.88629  ? 250 LEU B HD11 1 
ATOM   8376 H HD12 . LEU B 1 250 ? -3.02258  -10.73546 -44.09052 1.000 38.88629  ? 250 LEU B HD12 1 
ATOM   8377 H HD13 . LEU B 1 250 ? -2.55105  -11.27196 -42.67160 1.000 38.88629  ? 250 LEU B HD13 1 
ATOM   8378 H HD21 . LEU B 1 250 ? -3.54897  -8.08051  -41.10912 1.000 40.61085  ? 250 LEU B HD21 1 
ATOM   8379 H HD22 . LEU B 1 250 ? -4.25020  -9.50553  -41.14221 1.000 40.61085  ? 250 LEU B HD22 1 
ATOM   8380 H HD23 . LEU B 1 250 ? -2.75368  -9.36848  -40.62728 1.000 40.61085  ? 250 LEU B HD23 1 
ATOM   8381 N N    . GLY B 1 251 ? 1.26909   -6.65326  -43.10910 1.000 40.06388  ? 251 GLY B N    1 
ATOM   8382 C CA   . GLY B 1 251 ? 2.70469   -6.66405  -42.94387 1.000 36.11106  ? 251 GLY B CA   1 
ATOM   8383 C C    . GLY B 1 251 ? 3.19086   -6.11861  -41.61520 1.000 39.69332  ? 251 GLY B C    1 
ATOM   8384 O O    . GLY B 1 251 ? 4.00433   -6.74312  -40.92686 1.000 39.78581  ? 251 GLY B O    1 
ATOM   8385 H H    . GLY B 1 251 ? 1.00404   -6.17781  -43.77491 1.000 48.07043  ? 251 GLY B H    1 
ATOM   8386 H HA2  . GLY B 1 251 ? 3.02147   -7.57746  -43.02280 1.000 43.32704  ? 251 GLY B HA2  1 
ATOM   8387 H HA3  . GLY B 1 251 ? 3.10428   -6.12928  -43.64760 1.000 43.32704  ? 251 GLY B HA3  1 
ATOM   8388 N N    . PRO B 1 252 ? 2.73264   -4.92006  -41.24544 1.000 38.23916  ? 252 PRO B N    1 
ATOM   8389 C CA   . PRO B 1 252 ? 3.10391   -4.37165  -39.92877 1.000 36.45965  ? 252 PRO B CA   1 
ATOM   8390 C C    . PRO B 1 252 ? 2.82267   -5.31542  -38.77049 1.000 40.96469  ? 252 PRO B C    1 
ATOM   8391 O O    . PRO B 1 252 ? 3.65088   -5.42907  -37.85852 1.000 38.29458  ? 252 PRO B O    1 
ATOM   8392 C CB   . PRO B 1 252 ? 2.25622   -3.09519  -39.83709 1.000 34.59741  ? 252 PRO B CB   1 
ATOM   8393 C CG   . PRO B 1 252 ? 2.06238   -2.67596  -41.25098 1.000 45.34781  ? 252 PRO B CG   1 
ATOM   8394 C CD   . PRO B 1 252 ? 1.99413   -3.94464  -42.06649 1.000 41.61411  ? 252 PRO B CD   1 
ATOM   8395 H HA   . PRO B 1 252 ? 4.04552   -4.13870  -39.92854 1.000 43.74535  ? 252 PRO B HA   1 
ATOM   8396 H HB2  . PRO B 1 252 ? 1.40682   -3.29018  -39.41118 1.000 41.51066  ? 252 PRO B HB2  1 
ATOM   8397 H HB3  . PRO B 1 252 ? 2.73163   -2.41595  -39.33359 1.000 41.51066  ? 252 PRO B HB3  1 
ATOM   8398 H HG2  . PRO B 1 252 ? 1.23622   -2.17395  -41.33064 1.000 54.41115  ? 252 PRO B HG2  1 
ATOM   8399 H HG3  . PRO B 1 252 ? 2.81176   -2.12851  -41.53317 1.000 54.41115  ? 252 PRO B HG3  1 
ATOM   8400 H HD2  . PRO B 1 252 ? 1.07399   -4.22535  -42.19078 1.000 49.93070  ? 252 PRO B HD2  1 
ATOM   8401 H HD3  . PRO B 1 252 ? 2.42346   -3.82412  -42.92791 1.000 49.93070  ? 252 PRO B HD3  1 
ATOM   8402 N N    . LEU B 1 253 ? 1.67062   -5.98998  -38.77010 1.000 40.86607  ? 253 LEU B N    1 
ATOM   8403 C CA   . LEU B 1 253 ? 1.37993   -6.94023  -37.70109 1.000 38.22046  ? 253 LEU B CA   1 
ATOM   8404 C C    . LEU B 1 253 ? 2.35484   -8.11064  -37.73506 1.000 42.01655  ? 253 LEU B C    1 
ATOM   8405 O O    . LEU B 1 253 ? 2.88973   -8.51751  -36.69743 1.000 37.29139  ? 253 LEU B O    1 
ATOM   8406 C CB   . LEU B 1 253 ? -0.06209  -7.43798  -37.80941 1.000 37.60531  ? 253 LEU B CB   1 
ATOM   8407 C CG   . LEU B 1 253 ? -1.17211  -6.46328  -37.40701 1.000 43.19552  ? 253 LEU B CG   1 
ATOM   8408 C CD1  . LEU B 1 253 ? -2.53570  -7.12395  -37.54789 1.000 39.64432  ? 253 LEU B CD1  1 
ATOM   8409 C CD2  . LEU B 1 253 ? -0.97312  -5.96499  -35.98854 1.000 43.72135  ? 253 LEU B CD2  1 
ATOM   8410 H H    . LEU B 1 253 ? 1.05446   -5.91612  -39.36550 1.000 49.03306  ? 253 LEU B H    1 
ATOM   8411 H HA   . LEU B 1 253 ? 1.47475   -6.48740  -36.84854 1.000 45.85832  ? 253 LEU B HA   1 
ATOM   8412 H HB2  . LEU B 1 253 ? -0.22361  -7.68288  -38.73399 1.000 45.12015  ? 253 LEU B HB2  1 
ATOM   8413 H HB3  . LEU B 1 253 ? -0.15131  -8.21764  -37.23925 1.000 45.12015  ? 253 LEU B HB3  1 
ATOM   8414 H HG   . LEU B 1 253 ? -1.13882  -5.69554  -37.99893 1.000 51.82840  ? 253 LEU B HG   1 
ATOM   8415 H HD11 . LEU B 1 253 ? -2.64835  -7.77103  -36.83410 1.000 47.56696  ? 253 LEU B HD11 1 
ATOM   8416 H HD12 . LEU B 1 253 ? -3.22409  -6.44313  -37.48884 1.000 47.56696  ? 253 LEU B HD12 1 
ATOM   8417 H HD13 . LEU B 1 253 ? -2.58358  -7.56901  -38.40842 1.000 47.56696  ? 253 LEU B HD13 1 
ATOM   8418 H HD21 . LEU B 1 253 ? -0.86300  -6.72708  -35.39864 1.000 52.45939  ? 253 LEU B HD21 1 
ATOM   8419 H HD22 . LEU B 1 253 ? -0.18087  -5.40613  -35.95837 1.000 52.45939  ? 253 LEU B HD22 1 
ATOM   8420 H HD23 . LEU B 1 253 ? -1.75119  -5.45046  -35.72250 1.000 52.45939  ? 253 LEU B HD23 1 
ATOM   8421 N N    . SER B 1 254 ? 2.59192   -8.67171  -38.92552 1.000 37.67370  ? 254 SER B N    1 
ATOM   8422 C CA   A SER B 1 254 ? 3.53913   -9.77502  -39.05063 0.710 40.35714  ? 254 SER B CA   1 
ATOM   8423 C CA   B SER B 1 254 ? 3.53524   -9.77835  -39.04049 0.290 40.54703  ? 254 SER B CA   1 
ATOM   8424 C C    . SER B 1 254 ? 4.90864   -9.38454  -38.51077 1.000 42.84177  ? 254 SER B C    1 
ATOM   8425 O O    . SER B 1 254 ? 5.54115   -10.15350 -37.77753 1.000 44.02075  ? 254 SER B O    1 
ATOM   8426 C CB   A SER B 1 254 ? 3.64115   -10.20403 -40.51490 0.710 40.22896  ? 254 SER B CB   1 
ATOM   8427 C CB   B SER B 1 254 ? 3.63049   -10.23616 -40.49590 0.290 40.84156  ? 254 SER B CB   1 
ATOM   8428 O OG   A SER B 1 254 ? 4.51644   -11.30543 -40.67228 0.710 44.66150  ? 254 SER B OG   1 
ATOM   8429 O OG   B SER B 1 254 ? 4.20258   -9.22990  -41.31160 0.290 40.64549  ? 254 SER B OG   1 
ATOM   8430 H H    A SER B 1 254 ? 2.22135   -8.43365  -39.66417 0.710 45.20221  ? 254 SER B H    1 
ATOM   8431 H H    B SER B 1 254 ? 2.22522   -8.43273  -39.66580 0.290 45.20221  ? 254 SER B H    1 
ATOM   8432 H HA   A SER B 1 254 ? 3.21721   -10.53072 -38.53470 0.710 48.42234  ? 254 SER B HA   1 
ATOM   8433 H HA   B SER B 1 254 ? 3.21115   -10.52474 -38.51250 0.290 48.65020  ? 254 SER B HA   1 
ATOM   8434 H HB2  A SER B 1 254 ? 2.75918   -10.45738 -40.82927 0.710 48.26852  ? 254 SER B HB2  1 
ATOM   8435 H HB2  B SER B 1 254 ? 4.18571   -11.03031 -40.54013 0.290 49.00364  ? 254 SER B HB2  1 
ATOM   8436 H HB3  A SER B 1 254 ? 3.97807   -9.45907  -41.03684 0.710 48.26852  ? 254 SER B HB3  1 
ATOM   8437 H HB3  B SER B 1 254 ? 2.73899   -10.43608 -40.82173 0.290 49.00364  ? 254 SER B HB3  1 
ATOM   8438 H HG   A SER B 1 254 ? 5.30651   -11.06979 -40.51149 0.710 53.58757  ? 254 SER B HG   1 
ATOM   8439 H HG   B SER B 1 254 ? 5.01231   -9.12570  -41.11391 0.290 48.76836  ? 254 SER B HG   1 
ATOM   8440 N N    . ALA B 1 255 ? 5.37878   -8.18398  -38.85786 1.000 40.38479  ? 255 ALA B N    1 
ATOM   8441 C CA   . ALA B 1 255 ? 6.70038   -7.74398  -38.42580 1.000 44.25413  ? 255 ALA B CA   1 
ATOM   8442 C C    . ALA B 1 255 ? 6.76033   -7.51127  -36.92321 1.000 46.16915  ? 255 ALA B C    1 
ATOM   8443 O O    . ALA B 1 255 ? 7.81966   -7.68741  -36.31035 1.000 45.88124  ? 255 ALA B O    1 
ATOM   8444 C CB   . ALA B 1 255 ? 7.09069   -6.46422  -39.16573 1.000 37.92188  ? 255 ALA B CB   1 
ATOM   8445 H H    . ALA B 1 255 ? 4.95425   -7.61144  -39.33908 1.000 48.45553  ? 255 ALA B H    1 
ATOM   8446 H HA   . ALA B 1 255 ? 7.34214   -8.43677  -38.64735 1.000 53.09873  ? 255 ALA B HA   1 
ATOM   8447 H HB1  . ALA B 1 255 ? 7.17084   -6.65885  -40.11262 1.000 45.50003  ? 255 ALA B HB1  1 
ATOM   8448 H HB2  . ALA B 1 255 ? 6.40359   -5.79465  -39.02266 1.000 45.50003  ? 255 ALA B HB2  1 
ATOM   8449 H HB3  . ALA B 1 255 ? 7.93951   -6.14615  -38.82041 1.000 45.50003  ? 255 ALA B HB3  1 
ATOM   8450 N N    . GLN B 1 256 ? 5.64643   -7.10653  -36.31520 1.000 42.96854  ? 256 GLN B N    1 
ATOM   8451 C CA   . GLN B 1 256 ? 5.65033   -6.83695  -34.88280 1.000 42.08330  ? 256 GLN B CA   1 
ATOM   8452 C C    . GLN B 1 256 ? 5.67618   -8.12249  -34.06576 1.000 49.44944  ? 256 GLN B C    1 
ATOM   8453 O O    . GLN B 1 256 ? 6.15265   -8.11770  -32.92476 1.000 50.73492  ? 256 GLN B O    1 
ATOM   8454 C CB   . GLN B 1 256 ? 4.43209   -5.99013  -34.52074 1.000 50.42991  ? 256 GLN B CB   1 
ATOM   8455 C CG   . GLN B 1 256 ? 4.15744   -5.86927  -33.03481 1.000 62.30794  ? 256 GLN B CG   1 
ATOM   8456 C CD   . GLN B 1 256 ? 2.99266   -4.94894  -32.74844 1.000 48.35213  ? 256 GLN B CD   1 
ATOM   8457 O OE1  . GLN B 1 256 ? 2.50071   -4.25757  -33.64136 1.000 59.37454  ? 256 GLN B OE1  1 
ATOM   8458 N NE2  . GLN B 1 256 ? 2.54076   -4.93616  -31.50136 1.000 58.70967  ? 256 GLN B NE2  1 
ATOM   8459 H H    . GLN B 1 256 ? 4.88900   -6.98272  -36.70323 1.000 51.55602  ? 256 GLN B H    1 
ATOM   8460 H HA   . GLN B 1 256 ? 6.44741   -6.33320  -34.65523 1.000 50.49373  ? 256 GLN B HA   1 
ATOM   8461 H HB2  . GLN B 1 256 ? 4.56739   -5.09372  -34.86576 1.000 60.50967  ? 256 GLN B HB2  1 
ATOM   8462 H HB3  . GLN B 1 256 ? 3.64821   -6.38846  -34.93034 1.000 60.50967  ? 256 GLN B HB3  1 
ATOM   8463 H HG2  . GLN B 1 256 ? 3.94662   -6.74580  -32.67683 1.000 74.76330  ? 256 GLN B HG2  1 
ATOM   8464 H HG3  . GLN B 1 256 ? 4.94309   -5.51071  -32.59312 1.000 74.76330  ? 256 GLN B HG3  1 
ATOM   8465 H HE21 . GLN B 1 256 ? 2.90894   -5.43510  -30.90545 1.000 70.44538  ? 256 GLN B HE21 1 
ATOM   8466 H HE22 . GLN B 1 256 ? 1.87961   -4.42893  -31.28875 1.000 70.44538  ? 256 GLN B HE22 1 
ATOM   8467 N N    . THR B 1 257 ? 5.18092   -9.22774  -34.62444 1.000 49.09349  ? 257 THR B N    1 
ATOM   8468 C CA   . THR B 1 257 ? 5.13382   -10.49557 -33.91152 1.000 47.54407  ? 257 THR B CA   1 
ATOM   8469 C C    . THR B 1 257 ? 6.17003   -11.50155 -34.38907 1.000 41.21855  ? 257 THR B C    1 
ATOM   8470 O O    . THR B 1 257 ? 6.35699   -12.52775 -33.72741 1.000 46.53218  ? 257 THR B O    1 
ATOM   8471 C CB   . THR B 1 257 ? 3.74026   -11.13491 -34.03823 1.000 43.92741  ? 257 THR B CB   1 
ATOM   8472 O OG1  . THR B 1 257 ? 3.38409   -11.25413 -35.42228 1.000 38.98114  ? 257 THR B OG1  1 
ATOM   8473 C CG2  . THR B 1 257 ? 2.69809   -10.30360 -33.31495 1.000 37.51562  ? 257 THR B CG2  1 
ATOM   8474 H H    . THR B 1 257 ? 4.86415   -9.26474  -35.42312 1.000 58.90596  ? 257 THR B H    1 
ATOM   8475 H HA   . THR B 1 257 ? 5.29886   -10.31618 -32.97265 1.000 57.04666  ? 257 THR B HA   1 
ATOM   8476 H HB   . THR B 1 257 ? 3.75560   -12.01689 -33.63476 1.000 52.70666  ? 257 THR B HB   1 
ATOM   8477 H HG1  . THR B 1 257 ? 2.84532   -11.89010 -35.52653 1.000 46.77114  ? 257 THR B HG1  1 
ATOM   8478 H HG21 . THR B 1 257 ? 2.55604   -10.65370 -32.42155 1.000 45.01252  ? 257 THR B HG21 1 
ATOM   8479 H HG22 . THR B 1 257 ? 2.99583   -9.38282  -33.24857 1.000 45.01252  ? 257 THR B HG22 1 
ATOM   8480 H HG23 . THR B 1 257 ? 1.85850   -10.32877 -33.80009 1.000 45.01252  ? 257 THR B HG23 1 
ATOM   8481 N N    . GLY B 1 258 ? 6.83827   -11.24456 -35.51042 1.000 42.56604  ? 258 GLY B N    1 
ATOM   8482 C CA   . GLY B 1 258 ? 7.77619   -12.20575 -36.05702 1.000 44.35360  ? 258 GLY B CA   1 
ATOM   8483 C C    . GLY B 1 258 ? 7.12589   -13.46289 -36.58782 1.000 48.21108  ? 258 GLY B C    1 
ATOM   8484 O O    . GLY B 1 258 ? 7.75882   -14.52359 -36.59985 1.000 52.49580  ? 258 GLY B O    1 
ATOM   8485 H H    . GLY B 1 258 ? 6.76366   -10.52125 -35.96962 1.000 51.07302  ? 258 GLY B H    1 
ATOM   8486 H HA2  . GLY B 1 258 ? 8.26386   -11.79017 -36.78528 1.000 53.21809  ? 258 GLY B HA2  1 
ATOM   8487 H HA3  . GLY B 1 258 ? 8.40333   -12.46280 -35.36311 1.000 53.21809  ? 258 GLY B HA3  1 
ATOM   8488 N N    . ILE B 1 259 ? 5.87060   -13.37440 -37.02004 1.000 52.38906  ? 259 ILE B N    1 
ATOM   8489 C CA   . ILE B 1 259 ? 5.12725   -14.50603 -37.56092 1.000 45.89177  ? 259 ILE B CA   1 
ATOM   8490 C C    . ILE B 1 259 ? 4.72334   -14.15566 -38.98318 1.000 47.77058  ? 259 ILE B C    1 
ATOM   8491 O O    . ILE B 1 259 ? 3.96129   -13.20425 -39.20069 1.000 44.02609  ? 259 ILE B O    1 
ATOM   8492 C CB   . ILE B 1 259 ? 3.89003   -14.84283 -36.71359 1.000 47.71600  ? 259 ILE B CB   1 
ATOM   8493 C CG1  . ILE B 1 259 ? 4.31648   -15.32993 -35.32653 1.000 45.25527  ? 259 ILE B CG1  1 
ATOM   8494 C CG2  . ILE B 1 259 ? 3.02346   -15.87791 -37.43730 1.000 45.61901  ? 259 ILE B CG2  1 
ATOM   8495 C CD1  . ILE B 1 259 ? 3.17709   -15.41376 -34.32409 1.000 51.10001  ? 259 ILE B CD1  1 
ATOM   8496 H H    . ILE B 1 259 ? 5.41514   -12.64500 -37.00908 1.000 62.86064  ? 259 ILE B H    1 
ATOM   8497 H HA   . ILE B 1 259 ? 5.70364   -15.28592 -37.58213 1.000 55.06390  ? 259 ILE B HA   1 
ATOM   8498 H HB   . ILE B 1 259 ? 3.35777   -14.04094 -36.59284 1.000 57.25297  ? 259 ILE B HB   1 
ATOM   8499 H HG12 . ILE B 1 259 ? 4.69971   -16.21685 -35.41257 1.000 54.30009  ? 259 ILE B HG12 1 
ATOM   8500 H HG13 . ILE B 1 259 ? 4.97781   -14.71584 -34.97095 1.000 54.30009  ? 259 ILE B HG13 1 
ATOM   8501 H HG21 . ILE B 1 259 ? 2.47284   -15.42459 -38.09474 1.000 54.73658  ? 259 ILE B HG21 1 
ATOM   8502 H HG22 . ILE B 1 259 ? 3.60102   -16.52150 -37.87676 1.000 54.73658  ? 259 ILE B HG22 1 
ATOM   8503 H HG23 . ILE B 1 259 ? 2.46052   -16.32788 -36.78805 1.000 54.73658  ? 259 ILE B HG23 1 
ATOM   8504 H HD11 . ILE B 1 259 ? 2.47152   -15.96745 -34.69354 1.000 61.31379  ? 259 ILE B HD11 1 
ATOM   8505 H HD12 . ILE B 1 259 ? 3.50867   -15.80590 -33.50118 1.000 61.31379  ? 259 ILE B HD12 1 
ATOM   8506 H HD13 . ILE B 1 259 ? 2.84087   -14.52018 -34.15271 1.000 61.31379  ? 259 ILE B HD13 1 
ATOM   8507 N N    . ALA B 1 260 ? 5.23519   -14.91808 -39.94669 1.000 52.62860  ? 260 ALA B N    1 
ATOM   8508 C CA   . ALA B 1 260 ? 4.89650   -14.68648 -41.34223 1.000 54.67315  ? 260 ALA B CA   1 
ATOM   8509 C C    . ALA B 1 260 ? 3.38701   -14.67919 -41.52386 1.000 45.51585  ? 260 ALA B C    1 
ATOM   8510 O O    . ALA B 1 260 ? 2.66681   -15.45579 -40.89066 1.000 50.98734  ? 260 ALA B O    1 
ATOM   8511 C CB   . ALA B 1 260 ? 5.51793   -15.76744 -42.22740 1.000 58.93436  ? 260 ALA B CB   1 
ATOM   8512 H H    . ALA B 1 260 ? 5.77816   -15.57223 -39.81685 1.000 63.14809  ? 260 ALA B H    1 
ATOM   8513 H HA   . ALA B 1 260 ? 5.25064   -13.82686 -41.61887 1.000 65.60155  ? 260 ALA B HA   1 
ATOM   8514 H HB1  . ALA B 1 260 ? 5.17877   -16.63381 -41.95304 1.000 70.71501  ? 260 ALA B HB1  1 
ATOM   8515 H HB2  . ALA B 1 260 ? 5.27773   -15.59565 -43.15135 1.000 70.71501  ? 260 ALA B HB2  1 
ATOM   8516 H HB3  . ALA B 1 260 ? 6.48232   -15.74259 -42.12623 1.000 70.71501  ? 260 ALA B HB3  1 
ATOM   8517 N N    . VAL B 1 261 ? 2.91129   -13.79079 -42.39951 1.000 41.61287  ? 261 VAL B N    1 
ATOM   8518 C CA   . VAL B 1 261 ? 1.49150   -13.77454 -42.74120 1.000 43.54626  ? 261 VAL B CA   1 
ATOM   8519 C C    . VAL B 1 261 ? 1.01447   -15.18183 -43.07525 1.000 43.55326  ? 261 VAL B C    1 
ATOM   8520 O O    . VAL B 1 261 ? -0.09477  -15.58503 -42.70565 1.000 46.45427  ? 261 VAL B O    1 
ATOM   8521 C CB   . VAL B 1 261 ? 1.23741   -12.79803 -43.90661 1.000 45.64536  ? 261 VAL B CB   1 
ATOM   8522 C CG1  . VAL B 1 261 ? -0.12155  -13.05451 -44.54564 1.000 48.11302  ? 261 VAL B CG1  1 
ATOM   8523 C CG2  . VAL B 1 261 ? 1.33538   -11.35287 -43.42852 1.000 45.72150  ? 261 VAL B CG2  1 
ATOM   8524 H H    . VAL B 1 261 ? 3.38366   -13.19616 -42.80310 1.000 49.92921  ? 261 VAL B H    1 
ATOM   8525 H HA   . VAL B 1 261 ? 0.98842   -13.46130 -41.97330 1.000 52.24928  ? 261 VAL B HA   1 
ATOM   8526 H HB   . VAL B 1 261 ? 1.91898   -12.94354 -44.58128 1.000 54.76820  ? 261 VAL B HB   1 
ATOM   8527 H HG11 . VAL B 1 261 ? -0.35377  -12.29896 -45.10790 1.000 57.72940  ? 261 VAL B HG11 1 
ATOM   8528 H HG12 . VAL B 1 261 ? -0.07155  -13.86201 -45.08075 1.000 57.72940  ? 261 VAL B HG12 1 
ATOM   8529 H HG13 . VAL B 1 261 ? -0.78443  -13.16204 -43.84570 1.000 57.72940  ? 261 VAL B HG13 1 
ATOM   8530 H HG21 . VAL B 1 261 ? 1.52873   -11.34711 -42.47801 1.000 54.85957  ? 261 VAL B HG21 1 
ATOM   8531 H HG22 . VAL B 1 261 ? 2.04747   -10.90734 -43.91364 1.000 54.85957  ? 261 VAL B HG22 1 
ATOM   8532 H HG23 . VAL B 1 261 ? 0.49080   -10.90656 -43.59699 1.000 54.85957  ? 261 VAL B HG23 1 
ATOM   8533 N N    . LEU B 1 262 ? 1.85446   -15.96050 -43.75449 1.000 54.07722  ? 262 LEU B N    1 
ATOM   8534 C CA   . LEU B 1 262 ? 1.44220   -17.26396 -44.25777 1.000 46.61090  ? 262 LEU B CA   1 
ATOM   8535 C C    . LEU B 1 262 ? 1.58225   -18.36938 -43.22304 1.000 41.76442  ? 262 LEU B C    1 
ATOM   8536 O O    . LEU B 1 262 ? 0.88290   -19.38287 -43.32682 1.000 51.84361  ? 262 LEU B O    1 
ATOM   8537 C CB   . LEU B 1 262 ? 2.23769   -17.59652 -45.52426 1.000 40.88785  ? 262 LEU B CB   1 
ATOM   8538 C CG   . LEU B 1 262 ? 1.98982   -16.54753 -46.61790 1.000 47.37656  ? 262 LEU B CG   1 
ATOM   8539 C CD1  . LEU B 1 262 ? 3.29742   -16.04254 -47.20659 1.000 64.37747  ? 262 LEU B CD1  1 
ATOM   8540 C CD2  . LEU B 1 262 ? 1.08017   -17.08960 -47.71147 1.000 48.14011  ? 262 LEU B CD2  1 
ATOM   8541 H H    . LEU B 1 262 ? 2.66938   -15.75437 -43.93618 1.000 64.88643  ? 262 LEU B H    1 
ATOM   8542 H HA   . LEU B 1 262 ? 0.50517   -17.23864 -44.50723 1.000 55.92685  ? 262 LEU B HA   1 
ATOM   8543 H HB2  . LEU B 1 262 ? 3.18503   -17.60770 -45.31610 1.000 49.05919  ? 262 LEU B HB2  1 
ATOM   8544 H HB3  . LEU B 1 262 ? 1.96149   -18.46370 -45.85983 1.000 49.05919  ? 262 LEU B HB3  1 
ATOM   8545 H HG   . LEU B 1 262 ? 1.53944   -15.79185 -46.20924 1.000 56.84565  ? 262 LEU B HG   1 
ATOM   8546 H HD11 . LEU B 1 262 ? 3.80027   -15.58630 -46.51385 1.000 77.24674  ? 262 LEU B HD11 1 
ATOM   8547 H HD12 . LEU B 1 262 ? 3.80568   -16.79792 -47.54120 1.000 77.24674  ? 262 LEU B HD12 1 
ATOM   8548 H HD13 . LEU B 1 262 ? 3.10115   -15.42870 -47.93156 1.000 77.24674  ? 262 LEU B HD13 1 
ATOM   8549 H HD21 . LEU B 1 262 ? 0.83228   -16.36340 -48.30484 1.000 57.76190  ? 262 LEU B HD21 1 
ATOM   8550 H HD22 . LEU B 1 262 ? 1.55583   -17.77425 -48.20736 1.000 57.76190  ? 262 LEU B HD22 1 
ATOM   8551 H HD23 . LEU B 1 262 ? 0.28624   -17.46853 -47.30283 1.000 57.76190  ? 262 LEU B HD23 1 
ATOM   8552 N N    . ASP B 1 263 ? 2.44597   -18.19857 -42.22037 1.000 48.85809  ? 263 ASP B N    1 
ATOM   8553 C CA   . ASP B 1 263 ? 2.38547   -19.08029 -41.05995 1.000 52.01706  ? 263 ASP B CA   1 
ATOM   8554 C C    . ASP B 1 263 ? 1.05882   -18.90777 -40.33120 1.000 47.35092  ? 263 ASP B C    1 
ATOM   8555 O O    . ASP B 1 263 ? 0.41284   -19.89178 -39.95261 1.000 53.72407  ? 263 ASP B O    1 
ATOM   8556 C CB   . ASP B 1 263 ? 3.55317   -18.80267 -40.11071 1.000 55.24190  ? 263 ASP B CB   1 
ATOM   8557 C CG   . ASP B 1 263 ? 4.88697   -19.27980 -40.65977 1.000 59.99271  ? 263 ASP B CG   1 
ATOM   8558 O OD1  . ASP B 1 263 ? 4.89927   -20.19655 -41.50668 1.000 61.02679  ? 263 ASP B OD1  1 
ATOM   8559 O OD2  . ASP B 1 263 ? 5.92779   -18.73754 -40.23442 1.000 70.02019  ? 263 ASP B OD2  1 
ATOM   8560 H H    . ASP B 1 263 ? 3.05890   -17.59609 -42.18980 1.000 58.62347  ? 263 ASP B H    1 
ATOM   8561 H HA   . ASP B 1 263 ? 2.46413   -19.99964 -41.35912 1.000 62.41424  ? 263 ASP B HA   1 
ATOM   8562 H HB2  . ASP B 1 263 ? 3.61643   -17.84665 -39.95931 1.000 66.28405  ? 263 ASP B HB2  1 
ATOM   8563 H HB3  . ASP B 1 263 ? 3.39350   -19.26166 -39.27122 1.000 66.28405  ? 263 ASP B HB3  1 
ATOM   8564 N N    . MET B 1 264 ? 0.63178   -17.65758 -40.13540 1.000 47.57933  ? 264 MET B N    1 
ATOM   8565 C CA   . MET B 1 264 ? -0.65279  -17.40877 -39.49181 1.000 46.73048  ? 264 MET B CA   1 
ATOM   8566 C C    . MET B 1 264 ? -1.79373  -17.99119 -40.31575 1.000 41.72802  ? 264 MET B C    1 
ATOM   8567 O O    . MET B 1 264 ? -2.72396  -18.59087 -39.76433 1.000 45.64204  ? 264 MET B O    1 
ATOM   8568 C CB   . MET B 1 264 ? -0.85018  -15.90659 -39.28180 1.000 38.16113  ? 264 MET B CB   1 
ATOM   8569 C CG   . MET B 1 264 ? -2.03766  -15.55602 -38.40114 1.000 38.38687  ? 264 MET B CG   1 
ATOM   8570 S SD   . MET B 1 264 ? -1.74757  -15.92993 -36.65805 1.000 42.69792  ? 264 MET B SD   1 
ATOM   8571 C CE   . MET B 1 264 ? -1.03009  -14.38819 -36.09435 1.000 33.62497  ? 264 MET B CE   1 
ATOM   8572 H H    . MET B 1 264 ? 1.06189   -16.94856 -40.36321 1.000 57.08897  ? 264 MET B H    1 
ATOM   8573 H HA   . MET B 1 264 ? -0.65180  -17.82934 -38.61773 1.000 56.07035  ? 264 MET B HA   1 
ATOM   8574 H HB2  . MET B 1 264 ? -0.05435  -15.54427 -38.86194 1.000 45.78713  ? 264 MET B HB2  1 
ATOM   8575 H HB3  . MET B 1 264 ? -0.98958  -15.48771 -40.14552 1.000 45.78713  ? 264 MET B HB3  1 
ATOM   8576 H HG2  . MET B 1 264 ? -2.21909  -14.60627 -38.47824 1.000 46.05801  ? 264 MET B HG2  1 
ATOM   8577 H HG3  . MET B 1 264 ? -2.80940  -16.06599 -38.69312 1.000 46.05801  ? 264 MET B HG3  1 
ATOM   8578 H HE1  . MET B 1 264 ? -1.64007  -13.66239 -36.29940 1.000 40.34374  ? 264 MET B HE1  1 
ATOM   8579 H HE2  . MET B 1 264 ? -0.88600  -14.43852 -35.13643 1.000 40.34374  ? 264 MET B HE2  1 
ATOM   8580 H HE3  . MET B 1 264 ? -0.18479  -14.24833 -36.54911 1.000 40.34374  ? 264 MET B HE3  1 
ATOM   8581 N N    . CYS B 1 265 ? -1.73884  -17.82788 -41.64110 1.000 39.53329  ? 265 CYS B N    1 
ATOM   8582 C CA   . CYS B 1 265 ? -2.74758  -18.44039 -42.49977 1.000 44.74240  ? 265 CYS B CA   1 
ATOM   8583 C C    . CYS B 1 265 ? -2.81044  -19.94672 -42.28189 1.000 49.42298  ? 265 CYS B C    1 
ATOM   8584 O O    . CYS B 1 265 ? -3.89753  -20.53632 -42.27853 1.000 47.66939  ? 265 CYS B O    1 
ATOM   8585 C CB   . CYS B 1 265 ? -2.45169  -18.12878 -43.96581 1.000 39.86270  ? 265 CYS B CB   1 
ATOM   8586 S SG   . CYS B 1 265 ? -2.47246  -16.37409 -44.37828 1.000 51.56052  ? 265 CYS B SG   1 
ATOM   8587 H H    . CYS B 1 265 ? -1.13819  -17.37523 -42.05815 1.000 47.43372  ? 265 CYS B H    1 
ATOM   8588 H HA   . CYS B 1 265 ? -3.61392  -18.06316 -42.28056 1.000 53.68465  ? 265 CYS B HA   1 
ATOM   8589 H HB2  . CYS B 1 265 ? -1.56970  -18.46985 -44.18180 1.000 47.82902  ? 265 CYS B HB2  1 
ATOM   8590 H HB3  . CYS B 1 265 ? -3.12044  -18.56661 -44.51535 1.000 47.82902  ? 265 CYS B HB3  1 
ATOM   8591 H HG   . CYS B 1 265 ? -2.23880  -16.24498 -45.54821 1.000 61.86640  ? 265 CYS B HG   1 
ATOM   8592 N N    . ALA B 1 266 ? -1.65112  -20.58667 -42.09795 1.000 57.44192  ? 266 ALA B N    1 
ATOM   8593 C CA   . ALA B 1 266 ? -1.62851  -22.01721 -41.81212 1.000 58.18919  ? 266 ALA B CA   1 
ATOM   8594 C C    . ALA B 1 266 ? -2.31066  -22.33301 -40.48708 1.000 49.11878  ? 266 ALA B C    1 
ATOM   8595 O O    . ALA B 1 266 ? -2.87767  -23.41884 -40.32549 1.000 57.17190  ? 266 ALA B O    1 
ATOM   8596 C CB   . ALA B 1 266 ? -0.18676  -22.52777 -41.80274 1.000 65.63802  ? 266 ALA B CB   1 
ATOM   8597 H H    . ALA B 1 266 ? -0.87500  -20.21793 -42.13348 1.000 68.92407  ? 266 ALA B H    1 
ATOM   8598 H HA   . ALA B 1 266 ? -2.10708  -22.48406 -42.51490 1.000 69.82080  ? 266 ALA B HA   1 
ATOM   8599 H HB1  . ALA B 1 266 ? -0.19164  -23.48471 -41.64417 1.000 78.75939  ? 266 ALA B HB1  1 
ATOM   8600 H HB2  . ALA B 1 266 ? 0.22144   -22.33690 -42.66172 1.000 78.75939  ? 266 ALA B HB2  1 
ATOM   8601 H HB3  . ALA B 1 266 ? 0.30297   -22.07795 -41.09653 1.000 78.75939  ? 266 ALA B HB3  1 
ATOM   8602 N N    . SER B 1 267 ? -2.27223  -21.39930 -39.53243 1.000 54.16023  ? 267 SER B N    1 
ATOM   8603 C CA   . SER B 1 267 ? -2.98607  -21.59575 -38.27305 1.000 56.68060  ? 267 SER B CA   1 
ATOM   8604 C C    . SER B 1 267 ? -4.48928  -21.40717 -38.44683 1.000 52.36925  ? 267 SER B C    1 
ATOM   8605 O O    . SER B 1 267 ? -5.28446  -22.12174 -37.82447 1.000 47.78239  ? 267 SER B O    1 
ATOM   8606 C CB   . SER B 1 267 ? -2.45287  -20.63296 -37.21386 1.000 53.37591  ? 267 SER B CB   1 
ATOM   8607 O OG   . SER B 1 267 ? -1.06223  -20.81093 -37.02058 1.000 61.23582  ? 267 SER B OG   1 
ATOM   8608 H H    . SER B 1 267 ? -1.84603  -20.65451 -39.58932 1.000 64.98605  ? 267 SER B H    1 
ATOM   8609 H HA   . SER B 1 267 ? -2.82929  -22.50342 -37.96898 1.000 68.01049  ? 267 SER B HA   1 
ATOM   8610 H HB2  . SER B 1 267 ? -2.61655  -19.72223 -37.50487 1.000 64.04486  ? 267 SER B HB2  1 
ATOM   8611 H HB3  . SER B 1 267 ? -2.91153  -20.80096 -36.37582 1.000 64.04486  ? 267 SER B HB3  1 
ATOM   8612 H HG   . SER B 1 267 ? -0.64832  -20.63065 -37.72894 1.000 73.47675  ? 267 SER B HG   1 
ATOM   8613 N N    . LEU B 1 268 ? -4.90110  -20.44367 -39.27666 1.000 47.51820  ? 268 LEU B N    1 
ATOM   8614 C CA   . LEU B 1 268 ? -6.32473  -20.26831 -39.54688 1.000 48.99339  ? 268 LEU B CA   1 
ATOM   8615 C C    . LEU B 1 268 ? -6.88840  -21.47286 -40.28892 1.000 51.67494  ? 268 LEU B C    1 
ATOM   8616 O O    . LEU B 1 268 ? -7.97559  -21.96035 -39.95725 1.000 51.20563  ? 268 LEU B O    1 
ATOM   8617 C CB   . LEU B 1 268 ? -6.55353  -18.98482 -40.34497 1.000 46.09440  ? 268 LEU B CB   1 
ATOM   8618 C CG   . LEU B 1 268 ? -8.00355  -18.60720 -40.65292 1.000 38.96234  ? 268 LEU B CG   1 
ATOM   8619 C CD1  . LEU B 1 268 ? -8.83243  -18.56530 -39.38551 1.000 43.08627  ? 268 LEU B CD1  1 
ATOM   8620 C CD2  . LEU B 1 268 ? -8.05315  -17.26609 -41.36036 1.000 47.46764  ? 268 LEU B CD2  1 
ATOM   8621 H H    . LEU B 1 268 ? -4.38539  -19.89074 -39.68642 1.000 57.01562  ? 268 LEU B H    1 
ATOM   8622 H HA   . LEU B 1 268 ? -6.79910  -20.18181 -38.70521 1.000 58.78584  ? 268 LEU B HA   1 
ATOM   8623 H HB2  . LEU B 1 268 ? -6.17018  -18.24881 -39.84273 1.000 55.30705  ? 268 LEU B HB2  1 
ATOM   8624 H HB3  . LEU B 1 268 ? -6.09856  -19.07789 -41.19658 1.000 55.30705  ? 268 LEU B HB3  1 
ATOM   8625 H HG   . LEU B 1 268 ? -8.38756  -19.28051 -41.23609 1.000 46.74858  ? 268 LEU B HG   1 
ATOM   8626 H HD11 . LEU B 1 268 ? -9.69995  -18.18152 -39.58807 1.000 51.69729  ? 268 LEU B HD11 1 
ATOM   8627 H HD12 . LEU B 1 268 ? -8.94076  -19.46859 -39.04900 1.000 51.69729  ? 268 LEU B HD12 1 
ATOM   8628 H HD13 . LEU B 1 268 ? -8.37495  -18.01959 -38.72687 1.000 51.69729  ? 268 LEU B HD13 1 
ATOM   8629 H HD21 . LEU B 1 268 ? -7.28868  -17.19317 -41.95295 1.000 56.95494  ? 268 LEU B HD21 1 
ATOM   8630 H HD22 . LEU B 1 268 ? -8.87510  -17.20930 -41.87229 1.000 56.95494  ? 268 LEU B HD22 1 
ATOM   8631 H HD23 . LEU B 1 268 ? -8.02664  -16.55828 -40.69763 1.000 56.95494  ? 268 LEU B HD23 1 
ATOM   8632 N N    . LYS B 1 269 ? -6.15958  -21.96950 -41.29202 1.000 56.84990  ? 269 LYS B N    1 
ATOM   8633 C CA   . LYS B 1 269 ? -6.57952  -23.18195 -41.98794 1.000 55.90268  ? 269 LYS B CA   1 
ATOM   8634 C C    . LYS B 1 269 ? -6.76655  -24.33455 -41.00746 1.000 47.48122  ? 269 LYS B C    1 
ATOM   8635 O O    . LYS B 1 269 ? -7.77920  -25.04237 -41.04736 1.000 50.88158  ? 269 LYS B O    1 
ATOM   8636 C CB   . LYS B 1 269 ? -5.55428  -23.54719 -43.06237 1.000 53.83932  ? 269 LYS B CB   1 
ATOM   8637 H H    . LYS B 1 269 ? -5.42712  -21.62624 -41.58405 1.000 68.21365  ? 269 LYS B H    1 
ATOM   8638 H HA   . LYS B 1 269 ? -7.42906  -23.01680 -42.42601 1.000 67.07699  ? 269 LYS B HA   1 
ATOM   8639 N N    . GLU B 1 270 ? -5.79313  -24.53693 -40.11550 1.000 53.19743  ? 270 GLU B N    1 
ATOM   8640 C CA   . GLU B 1 270 ? -5.92848  -25.55787 -39.07867 1.000 48.73457  ? 270 GLU B CA   1 
ATOM   8641 C C    . GLU B 1 270 ? -7.15883  -25.30713 -38.21155 1.000 55.21300  ? 270 GLU B C    1 
ATOM   8642 O O    . GLU B 1 270 ? -7.85913  -26.25265 -37.82877 1.000 52.14984  ? 270 GLU B O    1 
ATOM   8643 C CB   . GLU B 1 270 ? -4.65086  -25.59567 -38.23160 1.000 52.00609  ? 270 GLU B CB   1 
ATOM   8644 C CG   . GLU B 1 270 ? -4.78283  -26.21582 -36.83818 1.000 74.50522  ? 270 GLU B CG   1 
ATOM   8645 C CD   . GLU B 1 270 ? -4.99105  -27.71778 -36.86457 1.000 72.28458  ? 270 GLU B CD   1 
ATOM   8646 O OE1  . GLU B 1 270 ? -4.30068  -28.40140 -37.64795 1.000 81.57251  ? 270 GLU B OE1  1 
ATOM   8647 O OE2  . GLU B 1 270 ? -5.84523  -28.21507 -36.09877 1.000 78.52425  ? 270 GLU B OE2  1 
ATOM   8648 H H    . GLU B 1 270 ? -5.05241  -24.10072 -40.08987 1.000 63.83069  ? 270 GLU B H    1 
ATOM   8649 H HA   . GLU B 1 270 ? -6.04031  -26.42728 -39.49402 1.000 58.47526  ? 270 GLU B HA   1 
ATOM   8650 H HB2  . GLU B 1 270 ? -3.98461  -26.11157 -38.71209 1.000 62.40107  ? 270 GLU B HB2  1 
ATOM   8651 H HB3  . GLU B 1 270 ? -4.34110  -24.68445 -38.11072 1.000 62.40107  ? 270 GLU B HB3  1 
ATOM   8652 H HG2  . GLU B 1 270 ? -3.97169  -26.03699 -36.33722 1.000 89.40003  ? 270 GLU B HG2  1 
ATOM   8653 H HG3  . GLU B 1 270 ? -5.54484  -25.81800 -36.38875 1.000 89.40003  ? 270 GLU B HG3  1 
ATOM   8654 N N    . LEU B 1 271 ? -7.43871  -24.03973 -37.89029 1.000 57.17963  ? 271 LEU B N    1 
ATOM   8655 C CA   . LEU B 1 271 ? -8.58915  -23.72220 -37.04696 1.000 54.00309  ? 271 LEU B CA   1 
ATOM   8656 C C    . LEU B 1 271 ? -9.90398  -24.04489 -37.74744 1.000 52.43950  ? 271 LEU B C    1 
ATOM   8657 O O    . LEU B 1 271 ? -10.82567 -24.58969 -37.12857 1.000 51.77041  ? 271 LEU B O    1 
ATOM   8658 C CB   . LEU B 1 271 ? -8.55627  -22.24653 -36.64496 1.000 54.18829  ? 271 LEU B CB   1 
ATOM   8659 C CG   . LEU B 1 271 ? -7.86494  -21.90392 -35.32409 1.000 59.87724  ? 271 LEU B CG   1 
ATOM   8660 C CD1  . LEU B 1 271 ? -7.68324  -20.39631 -35.18538 1.000 52.93630  ? 271 LEU B CD1  1 
ATOM   8661 C CD2  . LEU B 1 271 ? -8.65581  -22.45106 -34.14292 1.000 59.06580  ? 271 LEU B CD2  1 
ATOM   8662 H H    . LEU B 1 271 ? -6.98358  -23.35592 -38.14496 1.000 68.60932  ? 271 LEU B H    1 
ATOM   8663 H HA   . LEU B 1 271 ? -8.53515  -24.26071 -36.24198 1.000 64.79748  ? 271 LEU B HA   1 
ATOM   8664 H HB2  . LEU B 1 271 ? -8.09283  -21.75709 -37.34250 1.000 65.01972  ? 271 LEU B HB2  1 
ATOM   8665 H HB3  . LEU B 1 271 ? -9.47237  -21.93566 -36.57414 1.000 65.01972  ? 271 LEU B HB3  1 
ATOM   8666 H HG   . LEU B 1 271 ? -6.98733  -22.31704 -35.31812 1.000 71.84647  ? 271 LEU B HG   1 
ATOM   8667 H HD11 . LEU B 1 271 ? -8.54786  -19.98761 -35.02322 1.000 63.51734  ? 271 LEU B HD11 1 
ATOM   8668 H HD12 . LEU B 1 271 ? -7.08783  -20.21716 -34.44087 1.000 63.51734  ? 271 LEU B HD12 1 
ATOM   8669 H HD13 . LEU B 1 271 ? -7.30113  -20.04746 -36.00587 1.000 63.51734  ? 271 LEU B HD13 1 
ATOM   8670 H HD21 . LEU B 1 271 ? -9.55729  -22.09433 -34.17404 1.000 70.87273  ? 271 LEU B HD21 1 
ATOM   8671 H HD22 . LEU B 1 271 ? -8.68091  -23.41900 -34.20086 1.000 70.87273  ? 271 LEU B HD22 1 
ATOM   8672 H HD23 . LEU B 1 271 ? -8.22113  -22.18016 -33.31916 1.000 70.87273  ? 271 LEU B HD23 1 
ATOM   8673 N N    . LEU B 1 272 ? -10.01919 -23.69708 -39.03070 1.000 54.16540  ? 272 LEU B N    1 
ATOM   8674 C CA   . LEU B 1 272 ? -11.24735 -23.98649 -39.76347 1.000 52.72440  ? 272 LEU B CA   1 
ATOM   8675 C C    . LEU B 1 272 ? -11.45294 -25.48830 -39.92458 1.000 54.82337  ? 272 LEU B C    1 
ATOM   8676 O O    . LEU B 1 272 ? -12.58817 -25.97542 -39.86136 1.000 53.19716  ? 272 LEU B O    1 
ATOM   8677 C CB   . LEU B 1 272 ? -11.21435 -23.30001 -41.13030 1.000 54.22884  ? 272 LEU B CB   1 
ATOM   8678 C CG   . LEU B 1 272 ? -11.06298 -21.77500 -41.13438 1.000 44.55816  ? 272 LEU B CG   1 
ATOM   8679 C CD1  . LEU B 1 272 ? -10.86233 -21.25520 -42.55139 1.000 40.95162  ? 272 LEU B CD1  1 
ATOM   8680 C CD2  . LEU B 1 272 ? -12.26195 -21.09601 -40.49898 1.000 40.59931  ? 272 LEU B CD2  1 
ATOM   8681 H H    . LEU B 1 272 ? -9.41095  -23.29966 -39.49082 1.000 64.99225  ? 272 LEU B H    1 
ATOM   8682 H HA   . LEU B 1 272 ? -12.00033 -23.63153 -39.26554 1.000 63.26305  ? 272 LEU B HA   1 
ATOM   8683 H HB2  . LEU B 1 272 ? -10.46426 -23.66088 -41.62834 1.000 65.06838  ? 272 LEU B HB2  1 
ATOM   8684 H HB3  . LEU B 1 272 ? -12.04512 -23.50387 -41.58765 1.000 65.06838  ? 272 LEU B HB3  1 
ATOM   8685 H HG   . LEU B 1 272 ? -10.27942 -21.55140 -40.60813 1.000 53.46356  ? 272 LEU B HG   1 
ATOM   8686 H HD11 . LEU B 1 272 ? -10.78418 -20.28871 -42.52513 1.000 49.13572  ? 272 LEU B HD11 1 
ATOM   8687 H HD12 . LEU B 1 272 ? -10.05226 -21.64271 -42.91817 1.000 49.13572  ? 272 LEU B HD12 1 
ATOM   8688 H HD13 . LEU B 1 272 ? -11.62569 -21.51075 -43.09257 1.000 49.13572  ? 272 LEU B HD13 1 
ATOM   8689 H HD21 . LEU B 1 272 ? -12.47045 -21.54105 -39.66270 1.000 48.71294  ? 272 LEU B HD21 1 
ATOM   8690 H HD22 . LEU B 1 272 ? -12.04651 -20.16484 -40.33340 1.000 48.71294  ? 272 LEU B HD22 1 
ATOM   8691 H HD23 . LEU B 1 272 ? -13.01750 -21.15817 -41.10411 1.000 48.71294  ? 272 LEU B HD23 1 
ATOM   8692 N N    . GLN B 1 273 ? -10.36803 -26.24015 -40.12079 1.000 56.44100  ? 273 GLN B N    1 
ATOM   8693 C CA   . GLN B 1 273 ? -10.48952 -27.67153 -40.36881 1.000 56.60074  ? 273 GLN B CA   1 
ATOM   8694 C C    . GLN B 1 273 ? -10.79264 -28.44232 -39.08940 1.000 57.41117  ? 273 GLN B C    1 
ATOM   8695 O O    . GLN B 1 273 ? -11.57289 -29.40118 -39.10831 1.000 64.56394  ? 273 GLN B O    1 
ATOM   8696 C CB   . GLN B 1 273 ? -9.20435  -28.20074 -41.00769 1.000 58.06942  ? 273 GLN B CB   1 
ATOM   8697 C CG   . GLN B 1 273 ? -8.97704  -27.73966 -42.43625 1.000 48.97390  ? 273 GLN B CG   1 
ATOM   8698 C CD   . GLN B 1 273 ? -7.54034  -27.93584 -42.88882 1.000 59.77644  ? 273 GLN B CD   1 
ATOM   8699 O OE1  . GLN B 1 273 ? -6.66985  -28.29015 -42.09372 1.000 63.64005  ? 273 GLN B OE1  1 
ATOM   8700 N NE2  . GLN B 1 273 ? -7.28554  -27.70222 -44.17102 1.000 72.07381  ? 273 GLN B NE2  1 
ATOM   8701 H H    . GLN B 1 273 ? -9.55967  -25.94670 -40.11491 1.000 67.72298  ? 273 GLN B H    1 
ATOM   8702 H HA   . GLN B 1 273 ? -11.22185 -27.81688 -40.98805 1.000 67.91466  ? 273 GLN B HA   1 
ATOM   8703 H HB2  . GLN B 1 273 ? -8.44927  -27.89934 -40.47862 1.000 69.67708  ? 273 GLN B HB2  1 
ATOM   8704 H HB3  . GLN B 1 273 ? -9.23890  -29.17010 -41.01442 1.000 69.67708  ? 273 GLN B HB3  1 
ATOM   8705 H HG2  . GLN B 1 273 ? -9.55158  -28.24898 -43.02904 1.000 58.76246  ? 273 GLN B HG2  1 
ATOM   8706 H HG3  . GLN B 1 273 ? -9.18692  -26.79490 -42.50170 1.000 58.76246  ? 273 GLN B HG3  1 
ATOM   8707 H HE21 . GLN B 1 273 ? -7.91896  -27.45371 -44.69697 1.000 86.48235  ? 273 GLN B HE21 1 
ATOM   8708 H HE22 . GLN B 1 273 ? -6.48711  -27.79943 -44.47542 1.000 86.48235  ? 273 GLN B HE22 1 
ATOM   8709 N N    . ASN B 1 274 ? -10.19240 -28.03588 -37.97269 1.000 58.06071  ? 274 ASN B N    1 
ATOM   8710 C CA   . ASN B 1 274 ? -10.25910 -28.79600 -36.73398 1.000 61.54365  ? 274 ASN B CA   1 
ATOM   8711 C C    . ASN B 1 274 ? -11.17148 -28.17678 -35.68544 1.000 60.38017  ? 274 ASN B C    1 
ATOM   8712 O O    . ASN B 1 274 ? -11.30500 -28.74308 -34.59548 1.000 66.14621  ? 274 ASN B O    1 
ATOM   8713 C CB   . ASN B 1 274 ? -8.85168  -28.95628 -36.13906 1.000 60.06770  ? 274 ASN B CB   1 
ATOM   8714 C CG   . ASN B 1 274 ? -8.02313  -30.00091 -36.86142 1.000 64.43682  ? 274 ASN B CG   1 
ATOM   8715 O OD1  . ASN B 1 274 ? -7.28763  -29.69225 -37.80097 1.000 57.33612  ? 274 ASN B OD1  1 
ATOM   8716 N ND2  . ASN B 1 274 ? -8.13001  -31.24759 -36.41501 1.000 80.64804  ? 274 ASN B ND2  1 
ATOM   8717 H H    . ASN B 1 274 ? -9.73395  -27.31100 -37.90975 1.000 69.66663  ? 274 ASN B H    1 
ATOM   8718 H HA   . ASN B 1 274 ? -10.60935 -29.67580 -36.94415 1.000 73.84615  ? 274 ASN B HA   1 
ATOM   8719 H HB2  . ASN B 1 274 ? -8.38448  -28.10842 -36.20027 1.000 72.07502  ? 274 ASN B HB2  1 
ATOM   8720 H HB3  . ASN B 1 274 ? -8.93008  -29.22560 -35.21050 1.000 72.07502  ? 274 ASN B HB3  1 
ATOM   8721 H HD21 . ASN B 1 274 ? -7.68128  -31.87841 -36.78959 1.000 96.77142  ? 274 ASN B HD21 1 
ATOM   8722 H HD22 . ASN B 1 274 ? -8.64793  -31.42380 -35.75145 1.000 96.77142  ? 274 ASN B HD22 1 
ATOM   8723 N N    . GLY B 1 275 ? -11.80629 -27.04579 -35.97511 1.000 63.65012  ? 275 GLY B N    1 
ATOM   8724 C CA   . GLY B 1 275 ? -12.54179 -26.35336 -34.93743 1.000 58.62376  ? 275 GLY B CA   1 
ATOM   8725 C C    . GLY B 1 275 ? -11.59020 -25.82471 -33.87367 1.000 61.83875  ? 275 GLY B C    1 
ATOM   8726 O O    . GLY B 1 275 ? -10.36591 -25.86503 -34.00808 1.000 64.93417  ? 275 GLY B O    1 
ATOM   8727 H H    . GLY B 1 275 ? -11.82337 -26.67071 -36.74882 1.000 76.37391  ? 275 GLY B H    1 
ATOM   8728 H HA2  . GLY B 1 275 ? -13.02869 -25.60755 -35.32164 1.000 70.34228  ? 275 GLY B HA2  1 
ATOM   8729 H HA3  . GLY B 1 275 ? -13.17248 -26.96100 -34.52041 1.000 70.34228  ? 275 GLY B HA3  1 
ATOM   8730 N N    . MET B 1 276 ? -12.18315 -25.32390 -32.79230 1.000 55.75308  ? 276 MET B N    1 
ATOM   8731 C CA   . MET B 1 276 ? -11.41884 -24.75385 -31.69227 1.000 66.27864  ? 276 MET B CA   1 
ATOM   8732 C C    . MET B 1 276 ? -11.23654 -25.71813 -30.52709 1.000 79.28130  ? 276 MET B C    1 
ATOM   8733 O O    . MET B 1 276 ? -10.64296 -25.33440 -29.51507 1.000 75.30459  ? 276 MET B O    1 
ATOM   8734 C CB   . MET B 1 276 ? -12.08711 -23.46610 -31.19123 1.000 70.01815  ? 276 MET B CB   1 
ATOM   8735 C CG   . MET B 1 276 ? -11.81938 -22.24123 -32.06200 1.000 67.78425  ? 276 MET B CG   1 
ATOM   8736 S SD   . MET B 1 276 ? -12.08901 -20.68757 -31.18309 1.000 79.05250  ? 276 MET B SD   1 
ATOM   8737 C CE   . MET B 1 276 ? -11.95978 -19.51937 -32.53283 1.000 64.08625  ? 276 MET B CE   1 
ATOM   8738 H H    . MET B 1 276 ? -13.03475 -25.30399 -32.67405 1.000 66.89747  ? 276 MET B H    1 
ATOM   8739 H HA   . MET B 1 276 ? -10.54140 -24.51672 -32.03105 1.000 79.52814  ? 276 MET B HA   1 
ATOM   8740 H HB2  . MET B 1 276 ? -13.04683 -23.60468 -31.16574 1.000 84.01555  ? 276 MET B HB2  1 
ATOM   8741 H HB3  . MET B 1 276 ? -11.75622 -23.27160 -30.30040 1.000 84.01555  ? 276 MET B HB3  1 
ATOM   8742 H HG2  . MET B 1 276 ? -10.89657 -22.26098 -32.36022 1.000 81.33488  ? 276 MET B HG2  1 
ATOM   8743 H HG3  . MET B 1 276 ? -12.41568 -22.26065 -32.82683 1.000 81.33488  ? 276 MET B HG3  1 
ATOM   8744 H HE1  . MET B 1 276 ? -11.02827 -19.27661 -32.65229 1.000 76.89727  ? 276 MET B HE1  1 
ATOM   8745 H HE2  . MET B 1 276 ? -12.30030 -19.93247 -33.34172 1.000 76.89727  ? 276 MET B HE2  1 
ATOM   8746 H HE3  . MET B 1 276 ? -12.48235 -18.73065 -32.31898 1.000 76.89727  ? 276 MET B HE3  1 
ATOM   8747 N N    . ASN B 1 277 ? -11.71567 -26.95650 -30.64226 1.000 81.50428  ? 277 ASN B N    1 
ATOM   8748 C CA   . ASN B 1 277 ? -11.59934 -27.92988 -29.55710 1.000 80.83889  ? 277 ASN B CA   1 
ATOM   8749 C C    . ASN B 1 277 ? -12.08180 -27.32887 -28.23909 1.000 74.28006  ? 277 ASN B C    1 
ATOM   8750 O O    . ASN B 1 277 ? -11.50865 -27.56521 -27.17323 1.000 76.69959  ? 277 ASN B O    1 
ATOM   8751 C CB   . ASN B 1 277 ? -10.16098 -28.43484 -29.42879 1.000 105.30488 ? 277 ASN B CB   1 
ATOM   8752 H H    . ASN B 1 277 ? -12.11409 -27.25825 -31.34212 1.000 97.79891  ? 277 ASN B H    1 
ATOM   8753 H HA   . ASN B 1 277 ? -12.16575 -28.69021 -29.76202 1.000 97.00044  ? 277 ASN B HA   1 
ATOM   8754 N N    . GLY B 1 278 ? -13.14458 -26.53003 -28.31686 1.000 64.65274  ? 278 GLY B N    1 
ATOM   8755 C CA   . GLY B 1 278 ? -13.67126 -25.86578 -27.14307 1.000 65.57957  ? 278 GLY B CA   1 
ATOM   8756 C C    . GLY B 1 278 ? -12.80062 -24.76570 -26.58304 1.000 69.31891  ? 278 GLY B C    1 
ATOM   8757 O O    . GLY B 1 278 ? -13.10098 -24.24788 -25.50284 1.000 63.94589  ? 278 GLY B O    1 
ATOM   8758 H H    . GLY B 1 278 ? -13.57494 -26.36004 -29.04177 1.000 77.57706  ? 278 GLY B H    1 
ATOM   8759 H HA2  . GLY B 1 278 ? -14.53058 -25.47587 -27.36767 1.000 78.68926  ? 278 GLY B HA2  1 
ATOM   8760 H HA3  . GLY B 1 278 ? -13.79724 -26.52643 -26.44410 1.000 78.68926  ? 278 GLY B HA3  1 
ATOM   8761 N N    . ARG B 1 279 ? -11.72799 -24.39414 -27.27613 1.000 71.75305  ? 279 ARG B N    1 
ATOM   8762 C CA   . ARG B 1 279 ? -10.87055 -23.31010 -26.82812 1.000 71.97922  ? 279 ARG B CA   1 
ATOM   8763 C C    . ARG B 1 279 ? -11.50382 -21.95574 -27.13481 1.000 62.74755  ? 279 ARG B C    1 
ATOM   8764 O O    . ARG B 1 279 ? -12.44926 -21.83844 -27.91997 1.000 62.37098  ? 279 ARG B O    1 
ATOM   8765 C CB   . ARG B 1 279 ? -9.50217  -23.38666 -27.50358 1.000 71.28331  ? 279 ARG B CB   1 
ATOM   8766 C CG   . ARG B 1 279 ? -8.60110  -24.49133 -26.99481 1.000 66.42768  ? 279 ARG B CG   1 
ATOM   8767 C CD   . ARG B 1 279 ? -8.06292  -24.13276 -25.62665 1.000 72.68520  ? 279 ARG B CD   1 
ATOM   8768 N NE   . ARG B 1 279 ? -6.60540  -24.12870 -25.59410 1.000 64.29553  ? 279 ARG B NE   1 
ATOM   8769 C CZ   . ARG B 1 279 ? -5.87528  -23.39994 -24.75955 1.000 68.59994  ? 279 ARG B CZ   1 
ATOM   8770 N NH1  . ARG B 1 279 ? -6.43491  -22.57159 -23.89143 1.000 62.81702  ? 279 ARG B NH1  1 
ATOM   8771 N NH2  . ARG B 1 279 ? -4.54949  -23.49637 -24.80407 1.000 61.15998  ? 279 ARG B NH2  1 
ATOM   8772 H H    . ARG B 1 279 ? -11.47623 -24.75824 -28.01346 1.000 86.09743  ? 279 ARG B H    1 
ATOM   8773 H HA   . ARG B 1 279 ? -10.75266 -23.39311 -25.86889 1.000 86.36884  ? 279 ARG B HA   1 
ATOM   8774 H HB2  . ARG B 1 279 ? -9.63588  -23.53393 -28.45296 1.000 85.53375  ? 279 ARG B HB2  1 
ATOM   8775 H HB3  . ARG B 1 279 ? -9.04109  -22.54541 -27.36005 1.000 85.53375  ? 279 ARG B HB3  1 
ATOM   8776 H HG2  . ARG B 1 279 ? -9.10462  -25.31740 -26.92422 1.000 79.70698  ? 279 ARG B HG2  1 
ATOM   8777 H HG3  . ARG B 1 279 ? -7.85377  -24.60918 -27.60186 1.000 79.70698  ? 279 ARG B HG3  1 
ATOM   8778 H HD2  . ARG B 1 279 ? -8.37337  -23.24631 -25.38428 1.000 87.21601  ? 279 ARG B HD2  1 
ATOM   8779 H HD3  . ARG B 1 279 ? -8.37813  -24.78308 -24.97964 1.000 87.21601  ? 279 ARG B HD3  1 
ATOM   8780 H HE   . ARG B 1 279 ? -6.19064  -24.63292 -26.15386 1.000 77.14840  ? 279 ARG B HE   1 
ATOM   8781 H HH11 . ARG B 1 279 ? -7.29101  -22.49640 -23.85926 1.000 75.37419  ? 279 ARG B HH11 1 
ATOM   8782 H HH12 . ARG B 1 279 ? -5.94231  -22.10874 -23.35972 1.000 75.37419  ? 279 ARG B HH12 1 
ATOM   8783 H HH21 . ARG B 1 279 ? -4.17562  -24.02624 -25.36892 1.000 73.38575  ? 279 ARG B HH21 1 
ATOM   8784 H HH22 . ARG B 1 279 ? -4.06611  -23.02886 -24.26799 1.000 73.38575  ? 279 ARG B HH22 1 
ATOM   8785 N N    . THR B 1 280 ? -10.95733 -20.91911 -26.50399 1.000 56.72747  ? 280 THR B N    1 
ATOM   8786 C CA   . THR B 1 280 ? -11.31209 -19.54242 -26.80092 1.000 47.89925  ? 280 THR B CA   1 
ATOM   8787 C C    . THR B 1 280 ? -10.05894 -18.77213 -27.18984 1.000 46.97041  ? 280 THR B C    1 
ATOM   8788 O O    . THR B 1 280 ? -8.94140  -19.12461 -26.79772 1.000 45.04470  ? 280 THR B O    1 
ATOM   8789 C CB   . THR B 1 280 ? -11.98623 -18.84502 -25.61070 1.000 45.95641  ? 280 THR B CB   1 
ATOM   8790 O OG1  . THR B 1 280 ? -11.06179 -18.74159 -24.52060 1.000 40.93049  ? 280 THR B OG1  1 
ATOM   8791 C CG2  . THR B 1 280 ? -13.21922 -19.61336 -25.16922 1.000 44.98151  ? 280 THR B CG2  1 
ATOM   8792 H H    . THR B 1 280 ? -10.36448 -20.99435 -25.88555 1.000 68.06674  ? 280 THR B H    1 
ATOM   8793 H HA   . THR B 1 280 ? -11.93842 -19.53097 -27.54152 1.000 57.47288  ? 280 THR B HA   1 
ATOM   8794 H HB   . THR B 1 280 ? -12.26492 -17.95408 -25.87424 1.000 55.14147  ? 280 THR B HB   1 
ATOM   8795 H HG1  . THR B 1 280 ? -10.80053 -19.50647 -24.29191 1.000 49.11036  ? 280 THR B HG1  1 
ATOM   8796 H HG21 . THR B 1 280 ? -13.81318 -19.74947 -25.92393 1.000 53.97159  ? 280 THR B HG21 1 
ATOM   8797 H HG22 . THR B 1 280 ? -12.96134 -20.47742 -24.81175 1.000 53.97159  ? 280 THR B HG22 1 
ATOM   8798 H HG23 . THR B 1 280 ? -13.69134 -19.11681 -24.48261 1.000 53.97159  ? 280 THR B HG23 1 
ATOM   8799 N N    . ILE B 1 281 ? -10.26145 -17.71807 -27.97159 1.000 39.16922  ? 281 ILE B N    1 
ATOM   8800 C CA   . ILE B 1 281 ? -9.19720  -16.81606 -28.38829 1.000 37.85252  ? 281 ILE B CA   1 
ATOM   8801 C C    . ILE B 1 281 ? -9.64719  -15.41052 -28.02037 1.000 38.13587  ? 281 ILE B C    1 
ATOM   8802 O O    . ILE B 1 281 ? -10.71180 -14.96067 -28.46130 1.000 36.20856  ? 281 ILE B O    1 
ATOM   8803 C CB   . ILE B 1 281 ? -8.89794  -16.93900 -29.89274 1.000 41.13135  ? 281 ILE B CB   1 
ATOM   8804 C CG1  . ILE B 1 281 ? -8.40153  -18.35625 -30.20663 1.000 38.87470  ? 281 ILE B CG1  1 
ATOM   8805 C CG2  . ILE B 1 281 ? -7.88046  -15.89304 -30.34289 1.000 35.09105  ? 281 ILE B CG2  1 
ATOM   8806 C CD1  . ILE B 1 281 ? -8.03604  -18.58333 -31.65863 1.000 38.11181  ? 281 ILE B CD1  1 
ATOM   8807 H H    . ILE B 1 281 ? -11.03246 -17.49854 -28.28297 1.000 46.99683  ? 281 ILE B H    1 
ATOM   8808 H HA   . ILE B 1 281 ? -8.37560  -17.01211 -27.91138 1.000 45.41679  ? 281 ILE B HA   1 
ATOM   8809 H HB   . ILE B 1 281 ? -9.71897  -16.77582 -30.38282 1.000 49.35139  ? 281 ILE B HB   1 
ATOM   8810 H HG12 . ILE B 1 281 ? -7.61017  -18.53202 -29.67395 1.000 46.64341  ? 281 ILE B HG12 1 
ATOM   8811 H HG13 . ILE B 1 281 ? -9.10203  -18.98717 -29.97828 1.000 46.64341  ? 281 ILE B HG13 1 
ATOM   8812 H HG21 . ILE B 1 281 ? -8.21395  -15.45011 -31.13882 1.000 42.10304  ? 281 ILE B HG21 1 
ATOM   8813 H HG22 . ILE B 1 281 ? -7.75715  -15.24562 -29.63117 1.000 42.10304  ? 281 ILE B HG22 1 
ATOM   8814 H HG23 . ILE B 1 281 ? -7.03903  -16.33444 -30.53797 1.000 42.10304  ? 281 ILE B HG23 1 
ATOM   8815 H HD11 . ILE B 1 281 ? -7.85159  -19.52594 -31.79416 1.000 45.72794  ? 281 ILE B HD11 1 
ATOM   8816 H HD12 . ILE B 1 281 ? -8.77903  -18.30790 -32.21810 1.000 45.72794  ? 281 ILE B HD12 1 
ATOM   8817 H HD13 . ILE B 1 281 ? -7.24887  -18.05823 -31.87200 1.000 45.72794  ? 281 ILE B HD13 1 
ATOM   8818 N N    . LEU B 1 282 ? -8.84812  -14.72562 -27.20438 1.000 36.93307  ? 282 LEU B N    1 
ATOM   8819 C CA   . LEU B 1 282 ? -9.24802  -13.44224 -26.63404 1.000 35.71199  ? 282 LEU B CA   1 
ATOM   8820 C C    . LEU B 1 282 ? -10.63692 -13.54928 -26.01179 1.000 38.96837  ? 282 LEU B C    1 
ATOM   8821 O O    . LEU B 1 282 ? -11.48908 -12.67290 -26.17449 1.000 44.60797  ? 282 LEU B O    1 
ATOM   8822 C CB   . LEU B 1 282 ? -9.19722  -12.33571 -27.68638 1.000 39.00480  ? 282 LEU B CB   1 
ATOM   8823 C CG   . LEU B 1 282 ? -7.78858  -11.97656 -28.15951 1.000 40.69984  ? 282 LEU B CG   1 
ATOM   8824 C CD1  . LEU B 1 282 ? -7.83194  -11.23052 -29.48560 1.000 35.36233  ? 282 LEU B CD1  1 
ATOM   8825 C CD2  . LEU B 1 282 ? -7.08065  -11.14882 -27.09964 1.000 38.59066  ? 282 LEU B CD2  1 
ATOM   8826 H H    . LEU B 1 282 ? -8.06416  -14.98550 -26.96464 1.000 44.31346  ? 282 LEU B H    1 
ATOM   8827 H HA   . LEU B 1 282 ? -8.62482  -13.20250 -25.93045 1.000 42.84815  ? 282 LEU B HA   1 
ATOM   8828 H HB2  . LEU B 1 282 ? -9.70307  -12.62430 -28.46209 1.000 46.79953  ? 282 LEU B HB2  1 
ATOM   8829 H HB3  . LEU B 1 282 ? -9.59425  -11.53435 -27.31075 1.000 46.79953  ? 282 LEU B HB3  1 
ATOM   8830 H HG   . LEU B 1 282 ? -7.28366  -12.79251 -28.30159 1.000 48.83358  ? 282 LEU B HG   1 
ATOM   8831 H HD11 . LEU B 1 282 ? -6.92749  -11.13115 -29.82176 1.000 42.42857  ? 282 LEU B HD11 1 
ATOM   8832 H HD12 . LEU B 1 282 ? -8.36537  -11.73871 -30.11655 1.000 42.42857  ? 282 LEU B HD12 1 
ATOM   8833 H HD13 . LEU B 1 282 ? -8.22994  -10.35737 -29.34385 1.000 42.42857  ? 282 LEU B HD13 1 
ATOM   8834 H HD21 . LEU B 1 282 ? -7.59484  -10.34352 -26.93230 1.000 46.30257  ? 282 LEU B HD21 1 
ATOM   8835 H HD22 . LEU B 1 282 ? -7.01034  -11.67152 -26.28556 1.000 46.30257  ? 282 LEU B HD22 1 
ATOM   8836 H HD23 . LEU B 1 282 ? -6.19546  -10.91541 -27.42036 1.000 46.30257  ? 282 LEU B HD23 1 
ATOM   8837 N N    . GLY B 1 283 ? -10.86685 -14.65081 -25.29946 1.000 48.01469  ? 283 GLY B N    1 
ATOM   8838 C CA   . GLY B 1 283 ? -12.12801 -14.87316 -24.62679 1.000 40.94004  ? 283 GLY B CA   1 
ATOM   8839 C C    . GLY B 1 283 ? -13.30707 -15.13848 -25.53119 1.000 45.20287  ? 283 GLY B C    1 
ATOM   8840 O O    . GLY B 1 283 ? -14.43843 -15.19566 -25.04124 1.000 50.30034  ? 283 GLY B O    1 
ATOM   8841 H H    . GLY B 1 283 ? -10.29826 -15.28724 -25.19330 1.000 57.61140  ? 283 GLY B H    1 
ATOM   8842 H HA2  . GLY B 1 283 ? -12.03247 -15.63763 -24.03742 1.000 49.12182  ? 283 GLY B HA2  1 
ATOM   8843 H HA3  . GLY B 1 283 ? -12.33647 -14.08887 -24.09545 1.000 49.12182  ? 283 GLY B HA3  1 
ATOM   8844 N N    . SER B 1 284 ? -13.08851 -15.30561 -26.83224 1.000 50.06148  ? 284 SER B N    1 
ATOM   8845 C CA   . SER B 1 284 ? -14.16462 -15.55565 -27.77898 1.000 41.46819  ? 284 SER B CA   1 
ATOM   8846 C C    . SER B 1 284 ? -14.12959 -17.00671 -28.23559 1.000 42.68059  ? 284 SER B C    1 
ATOM   8847 O O    . SER B 1 284 ? -13.05951 -17.55551 -28.51593 1.000 44.55848  ? 284 SER B O    1 
ATOM   8848 C CB   . SER B 1 284 ? -14.06281 -14.62991 -28.99205 1.000 38.59007  ? 284 SER B CB   1 
ATOM   8849 O OG   . SER B 1 284 ? -15.07974 -14.93197 -29.92988 1.000 49.70117  ? 284 SER B OG   1 
ATOM   8850 H H    . SER B 1 284 ? -12.30920 -15.27750 -27.19485 1.000 60.06755  ? 284 SER B H    1 
ATOM   8851 H HA   . SER B 1 284 ? -15.01598 -15.39244 -27.34371 1.000 49.75559  ? 284 SER B HA   1 
ATOM   8852 H HB2  . SER B 1 284 ? -14.16362 -13.71064 -28.69935 1.000 46.30186  ? 284 SER B HB2  1 
ATOM   8853 H HB3  . SER B 1 284 ? -13.19703 -14.75121 -29.41232 1.000 46.30186  ? 284 SER B HB3  1 
ATOM   8854 H HG   . SER B 1 284 ? -15.82632 -14.95787 -29.54576 1.000 59.63518  ? 284 SER B HG   1 
ATOM   8855 N N    . ALA B 1 285 ? -15.30563 -17.62451 -28.30312 1.000 49.94727  ? 285 ALA B N    1 
ATOM   8856 C CA   . ALA B 1 285 ? -15.42792 -18.99277 -28.78161 1.000 50.00532  ? 285 ALA B CA   1 
ATOM   8857 C C    . ALA B 1 285 ? -15.54456 -19.07954 -30.29560 1.000 41.59728  ? 285 ALA B C    1 
ATOM   8858 O O    . ALA B 1 285 ? -15.55574 -20.18846 -30.83816 1.000 54.33672  ? 285 ALA B O    1 
ATOM   8859 C CB   . ALA B 1 285 ? -16.64174 -19.66832 -28.13795 1.000 51.70130  ? 285 ALA B CB   1 
ATOM   8860 H H    . ALA B 1 285 ? -16.05347 -17.26658 -28.07462 1.000 59.93050  ? 285 ALA B H    1 
ATOM   8861 H HA   . ALA B 1 285 ? -14.63789 -19.48873 -28.51558 1.000 60.00016  ? 285 ALA B HA   1 
ATOM   8862 H HB1  . ALA B 1 285 ? -16.76321 -20.54468 -28.53562 1.000 62.03534  ? 285 ALA B HB1  1 
ATOM   8863 H HB2  . ALA B 1 285 ? -16.48553 -19.75641 -27.18467 1.000 62.03534  ? 285 ALA B HB2  1 
ATOM   8864 H HB3  . ALA B 1 285 ? -17.42760 -19.12189 -28.29526 1.000 62.03534  ? 285 ALA B HB3  1 
ATOM   8865 N N    . LEU B 1 286 ? -15.62823 -17.94690 -30.98387 1.000 40.75031  ? 286 LEU B N    1 
ATOM   8866 C CA   . LEU B 1 286 ? -15.72074 -17.90927 -32.43376 1.000 40.70654  ? 286 LEU B CA   1 
ATOM   8867 C C    . LEU B 1 286 ? -14.66186 -16.95359 -32.96479 1.000 43.02530  ? 286 LEU B C    1 
ATOM   8868 O O    . LEU B 1 286 ? -14.09728 -16.14580 -32.22246 1.000 40.61686  ? 286 LEU B O    1 
ATOM   8869 C CB   . LEU B 1 286 ? -17.12377 -17.48132 -32.88505 1.000 43.29032  ? 286 LEU B CB   1 
ATOM   8870 C CG   . LEU B 1 286 ? -18.25569 -18.34826 -32.32406 1.000 65.46014  ? 286 LEU B CG   1 
ATOM   8871 C CD1  . LEU B 1 286 ? -19.60712 -17.68406 -32.53373 1.000 43.44275  ? 286 LEU B CD1  1 
ATOM   8872 C CD2  . LEU B 1 286 ? -18.23578 -19.74438 -32.94879 1.000 52.84758  ? 286 LEU B CD2  1 
ATOM   8873 H H    . LEU B 1 286 ? -15.63326 -17.16703 -30.62140 1.000 48.89415  ? 286 LEU B H    1 
ATOM   8874 H HA   . LEU B 1 286 ? -15.54665 -18.78616 -32.81015 1.000 48.84162  ? 286 LEU B HA   1 
ATOM   8875 H HB2  . LEU B 1 286 ? -17.27814 -16.56940 -32.59268 1.000 51.94216  ? 286 LEU B HB2  1 
ATOM   8876 H HB3  . LEU B 1 286 ? -17.16613 -17.53110 -33.85285 1.000 51.94216  ? 286 LEU B HB3  1 
ATOM   8877 H HG   . LEU B 1 286 ? -18.12057 -18.44810 -31.36872 1.000 78.54594  ? 286 LEU B HG   1 
ATOM   8878 H HD11 . LEU B 1 286 ? -20.29432 -18.22836 -32.11853 1.000 52.12507  ? 286 LEU B HD11 1 
ATOM   8879 H HD12 . LEU B 1 286 ? -19.59251 -16.80327 -32.12767 1.000 52.12507  ? 286 LEU B HD12 1 
ATOM   8880 H HD13 . LEU B 1 286 ? -19.77667 -17.60667 -33.48566 1.000 52.12507  ? 286 LEU B HD13 1 
ATOM   8881 H HD21 . LEU B 1 286 ? -17.44767 -20.21764 -32.63928 1.000 63.41087  ? 286 LEU B HD21 1 
ATOM   8882 H HD22 . LEU B 1 286 ? -19.03571 -20.22234 -32.67940 1.000 63.41087  ? 286 LEU B HD22 1 
ATOM   8883 H HD23 . LEU B 1 286 ? -18.21164 -19.65785 -33.91462 1.000 63.41087  ? 286 LEU B HD23 1 
ATOM   8884 N N    . LEU B 1 287 ? -14.38681 -17.06108 -34.26173 1.000 37.61490  ? 287 LEU B N    1 
ATOM   8885 C CA   . LEU B 1 287 ? -13.37763 -16.22328 -34.89649 1.000 38.51438  ? 287 LEU B CA   1 
ATOM   8886 C C    . LEU B 1 287 ? -13.99184 -14.86760 -35.22047 1.000 37.24553  ? 287 LEU B C    1 
ATOM   8887 O O    . LEU B 1 287 ? -14.98426 -14.79107 -35.95049 1.000 34.87054  ? 287 LEU B O    1 
ATOM   8888 C CB   . LEU B 1 287 ? -12.84516 -16.89679 -36.15771 1.000 44.10858  ? 287 LEU B CB   1 
ATOM   8889 C CG   . LEU B 1 287 ? -12.22288 -18.27719 -35.95098 1.000 43.83452  ? 287 LEU B CG   1 
ATOM   8890 C CD1  . LEU B 1 287 ? -12.06573 -18.98428 -37.28596 1.000 49.01164  ? 287 LEU B CD1  1 
ATOM   8891 C CD2  . LEU B 1 287 ? -10.88593 -18.16344 -35.24633 1.000 51.33795  ? 287 LEU B CD2  1 
ATOM   8892 H H    . LEU B 1 287 ? -14.77259 -17.61354 -34.79611 1.000 45.13165  ? 287 LEU B H    1 
ATOM   8893 H HA   . LEU B 1 287 ? -12.63121 -16.09003 -34.29151 1.000 46.21103  ? 287 LEU B HA   1 
ATOM   8894 H HB2  . LEU B 1 287 ? -13.58083 -17.00104 -36.78126 1.000 52.92407  ? 287 LEU B HB2  1 
ATOM   8895 H HB3  . LEU B 1 287 ? -12.16215 -16.32581 -36.54290 1.000 52.92407  ? 287 LEU B HB3  1 
ATOM   8896 H HG   . LEU B 1 287 ? -12.80829 -18.80927 -35.38965 1.000 52.59520  ? 287 LEU B HG   1 
ATOM   8897 H HD11 . LEU B 1 287 ? -12.94447 -19.20978 -37.62926 1.000 58.80774  ? 287 LEU B HD11 1 
ATOM   8898 H HD12 . LEU B 1 287 ? -11.61057 -18.39241 -37.90517 1.000 58.80774  ? 287 LEU B HD12 1 
ATOM   8899 H HD13 . LEU B 1 287 ? -11.54411 -19.79173 -37.15617 1.000 58.80774  ? 287 LEU B HD13 1 
ATOM   8900 H HD21 . LEU B 1 287 ? -10.23591 -17.78843 -35.86094 1.000 61.59932  ? 287 LEU B HD21 1 
ATOM   8901 H HD22 . LEU B 1 287 ? -10.98400 -17.58412 -34.47453 1.000 61.59932  ? 287 LEU B HD22 1 
ATOM   8902 H HD23 . LEU B 1 287 ? -10.60211 -19.04667 -34.96302 1.000 61.59932  ? 287 LEU B HD23 1 
ATOM   8903 N N    . GLU B 1 288 ? -13.41386 -13.80450 -34.66998 1.000 30.43691  ? 288 GLU B N    1 
ATOM   8904 C CA   . GLU B 1 288 ? -13.92678 -12.45868 -34.88468 1.000 32.98747  ? 288 GLU B CA   1 
ATOM   8905 C C    . GLU B 1 288 ? -13.37336 -11.87469 -36.17977 1.000 36.90034  ? 288 GLU B C    1 
ATOM   8906 O O    . GLU B 1 288 ? -12.19734 -12.05898 -36.50855 1.000 35.30813  ? 288 GLU B O    1 
ATOM   8907 C CB   . GLU B 1 288 ? -13.55641 -11.57170 -33.69521 1.000 40.97008  ? 288 GLU B CB   1 
ATOM   8908 C CG   . GLU B 1 288 ? -14.02463 -10.12579 -33.80125 1.000 54.81535  ? 288 GLU B CG   1 
ATOM   8909 C CD   . GLU B 1 288 ? -15.53452 -9.98886  -33.81482 1.000 51.10614  ? 288 GLU B CD   1 
ATOM   8910 O OE1  . GLU B 1 288 ? -16.19545 -10.55923 -32.91984 1.000 64.70639  ? 288 GLU B OE1  1 
ATOM   8911 O OE2  . GLU B 1 288 ? -16.05756 -9.31258  -34.72601 1.000 48.12578  ? 288 GLU B OE2  1 
ATOM   8912 H H    . GLU B 1 288 ? -12.71870 -13.83735 -34.16475 1.000 36.51806  ? 288 GLU B H    1 
ATOM   8913 H HA   . GLU B 1 288 ? -14.89346 -12.47965 -34.96206 1.000 39.57874  ? 288 GLU B HA   1 
ATOM   8914 H HB2  . GLU B 1 288 ? -13.95478 -11.94868 -32.89516 1.000 49.15787  ? 288 GLU B HB2  1 
ATOM   8915 H HB3  . GLU B 1 288 ? -12.59020 -11.55924 -33.61046 1.000 49.15787  ? 288 GLU B HB3  1 
ATOM   8916 H HG2  . GLU B 1 288 ? -13.68671 -9.62886  -33.03982 1.000 65.77220  ? 288 GLU B HG2  1 
ATOM   8917 H HG3  . GLU B 1 288 ? -13.68289 -9.74386  -34.62481 1.000 65.77220  ? 288 GLU B HG3  1 
ATOM   8918 N N    . ASP B 1 289 ? -14.23104 -11.15091 -36.91797 1.000 32.22920  ? 289 ASP B N    1 
ATOM   8919 C CA   . ASP B 1 289 ? -13.80964 -10.62111 -38.20995 1.000 36.22849  ? 289 ASP B CA   1 
ATOM   8920 C C    . ASP B 1 289 ? -14.21097 -9.16339  -38.44121 1.000 32.29599  ? 289 ASP B C    1 
ATOM   8921 O O    . ASP B 1 289 ? -14.26039 -8.72584  -39.59808 1.000 42.11111  ? 289 ASP B O    1 
ATOM   8922 C CB   . ASP B 1 289 ? -14.36043 -11.50370 -39.35203 1.000 31.18709  ? 289 ASP B CB   1 
ATOM   8923 C CG   . ASP B 1 289 ? -15.83588 -11.26049 -39.64154 1.000 34.85385  ? 289 ASP B CG   1 
ATOM   8924 O OD1  . ASP B 1 289 ? -16.58418 -10.82265 -38.74100 1.000 33.50117  ? 289 ASP B OD1  1 
ATOM   8925 O OD2  . ASP B 1 289 ? -16.24621 -11.51732 -40.79148 1.000 36.38328  ? 289 ASP B OD2  1 
ATOM   8926 H H    . ASP B 1 289 ? -15.03918 -10.96157 -36.69289 1.000 38.66882  ? 289 ASP B H    1 
ATOM   8927 H HA   . ASP B 1 289 ? -12.84015 -10.63877 -38.23616 1.000 43.46796  ? 289 ASP B HA   1 
ATOM   8928 N N    . GLU B 1 290 ? -14.46156 -8.38016  -37.38889 1.000 29.75496  ? 290 GLU B N    1 
ATOM   8929 C CA   . GLU B 1 290 ? -14.78974 -6.96573  -37.54578 1.000 39.00305  ? 290 GLU B CA   1 
ATOM   8930 C C    . GLU B 1 290 ? -13.71650 -6.06476  -36.94103 1.000 33.86727  ? 290 GLU B C    1 
ATOM   8931 O O    . GLU B 1 290 ? -14.00628 -4.95626  -36.48410 1.000 38.56019  ? 290 GLU B O    1 
ATOM   8932 C CB   . GLU B 1 290 ? -16.16143 -6.64682  -36.94788 1.000 35.07002  ? 290 GLU B CB   1 
ATOM   8933 C CG   . GLU B 1 290 ? -17.29138 -7.44255  -37.59090 1.000 40.16931  ? 290 GLU B CG   1 
ATOM   8934 C CD   . GLU B 1 290 ? -18.64581 -6.75088  -37.52040 1.000 42.71990  ? 290 GLU B CD   1 
ATOM   8935 O OE1  . GLU B 1 290 ? -18.80217 -5.79683  -36.72963 1.000 47.41064  ? 290 GLU B OE1  1 
ATOM   8936 O OE2  . GLU B 1 290 ? -19.56001 -7.17050  -38.26272 1.000 38.52851  ? 290 GLU B OE2  1 
ATOM   8937 H H    . GLU B 1 290 ? -14.44674 -8.64901  -36.57212 1.000 35.69972  ? 290 GLU B H    1 
ATOM   8938 H HA   . GLU B 1 290 ? -14.83811 -6.77153  -38.49491 1.000 46.79743  ? 290 GLU B HA   1 
ATOM   8939 H HB2  . GLU B 1 290 ? -16.14853 -6.85697  -36.00100 1.000 42.07779  ? 290 GLU B HB2  1 
ATOM   8940 H HB3  . GLU B 1 290 ? -16.34895 -5.70377  -37.07588 1.000 42.07779  ? 290 GLU B HB3  1 
ATOM   8941 H HG2  . GLU B 1 290 ? -17.08011 -7.58431  -38.52694 1.000 48.19695  ? 290 GLU B HG2  1 
ATOM   8942 H HG3  . GLU B 1 290 ? -17.37090 -8.29550  -37.13588 1.000 48.19695  ? 290 GLU B HG3  1 
ATOM   8943 N N    . PHE B 1 291 ? -12.47346 -6.54019  -36.93054 1.000 32.45446  ? 291 PHE B N    1 
ATOM   8944 C CA   . PHE B 1 291 ? -11.30339 -5.72719  -36.62640 1.000 32.08301  ? 291 PHE B CA   1 
ATOM   8945 C C    . PHE B 1 291 ? -10.42679 -5.71216  -37.87011 1.000 29.01042  ? 291 PHE B C    1 
ATOM   8946 O O    . PHE B 1 291 ? -9.95333  -6.76726  -38.30508 1.000 29.87417  ? 291 PHE B O    1 
ATOM   8947 C CB   . PHE B 1 291 ? -10.52107 -6.28239  -35.43293 1.000 32.00144  ? 291 PHE B CB   1 
ATOM   8948 C CG   . PHE B 1 291 ? -11.24649 -6.17821  -34.12456 1.000 35.49992  ? 291 PHE B CG   1 
ATOM   8949 C CD1  . PHE B 1 291 ? -11.21391 -5.00268  -33.39150 1.000 40.17802  ? 291 PHE B CD1  1 
ATOM   8950 C CD2  . PHE B 1 291 ? -11.94504 -7.26007  -33.61661 1.000 37.63051  ? 291 PHE B CD2  1 
ATOM   8951 C CE1  . PHE B 1 291 ? -11.87506 -4.90351  -32.18348 1.000 40.58951  ? 291 PHE B CE1  1 
ATOM   8952 C CE2  . PHE B 1 291 ? -12.61076 -7.16626  -32.40682 1.000 44.75921  ? 291 PHE B CE2  1 
ATOM   8953 C CZ   . PHE B 1 291 ? -12.57542 -5.98685  -31.69021 1.000 38.01981  ? 291 PHE B CZ   1 
ATOM   8954 H H    . PHE B 1 291 ? -12.27806 -7.35980  -37.10278 1.000 38.93912  ? 291 PHE B H    1 
ATOM   8955 H HA   . PHE B 1 291 ? -11.57803 -4.82375  -36.40443 1.000 38.49339  ? 291 PHE B HA   1 
ATOM   8956 H HB2  . PHE B 1 291 ? -10.33494 -7.22084  -35.59286 1.000 38.39550  ? 291 PHE B HB2  1 
ATOM   8957 H HB3  . PHE B 1 291 ? -9.69016  -5.78892  -35.34939 1.000 38.39550  ? 291 PHE B HB3  1 
ATOM   8958 H HD1  . PHE B 1 291 ? -10.74074 -4.27135  -33.71734 1.000 48.20739  ? 291 PHE B HD1  1 
ATOM   8959 H HD2  . PHE B 1 291 ? -11.96723 -8.05830  -34.09331 1.000 45.15038  ? 291 PHE B HD2  1 
ATOM   8960 H HE1  . PHE B 1 291 ? -11.84883 -4.10803  -31.70242 1.000 48.70118  ? 291 PHE B HE1  1 
ATOM   8961 H HE2  . PHE B 1 291 ? -13.08157 -7.89727  -32.07689 1.000 53.70483  ? 291 PHE B HE2  1 
ATOM   8962 H HZ   . PHE B 1 291 ? -13.02221 -5.92196  -30.87714 1.000 45.61754  ? 291 PHE B HZ   1 
ATOM   8963 N N    . THR B 1 292 ? -10.23226 -4.53404  -38.45496 1.000 30.21540  ? 292 THR B N    1 
ATOM   8964 C CA   . THR B 1 292 ? -9.32825  -4.43359  -39.58879 1.000 35.18437  ? 292 THR B CA   1 
ATOM   8965 C C    . THR B 1 292 ? -7.88422  -4.49277  -39.10582 1.000 32.39655  ? 292 THR B C    1 
ATOM   8966 O O    . THR B 1 292 ? -7.60615  -4.32496  -37.91399 1.000 33.21637  ? 292 THR B O    1 
ATOM   8967 C CB   . THR B 1 292 ? -9.55931  -3.13766  -40.36333 1.000 36.06841  ? 292 THR B CB   1 
ATOM   8968 O OG1  . THR B 1 292 ? -9.24237  -2.01523  -39.52938 1.000 32.05655  ? 292 THR B OG1  1 
ATOM   8969 C CG2  . THR B 1 292 ? -11.01193 -3.04396  -40.86241 1.000 29.92487  ? 292 THR B CG2  1 
ATOM   8970 H H    . THR B 1 292 ? -10.60478 -3.79621  -38.21740 1.000 36.25226  ? 292 THR B H    1 
ATOM   8971 H HA   . THR B 1 292 ? -9.49479  -5.17005  -40.19771 1.000 42.21502  ? 292 THR B HA   1 
ATOM   8972 H HB   . THR B 1 292 ? -8.98460  -3.12012  -41.14455 1.000 43.27586  ? 292 THR B HB   1 
ATOM   8973 H HG1  . THR B 1 292 ? -9.49086  -1.30320  -39.89934 1.000 38.46163  ? 292 THR B HG1  1 
ATOM   8974 H HG21 . THR B 1 292 ? -11.33420 -3.92400  -41.11255 1.000 35.90362  ? 292 THR B HG21 1 
ATOM   8975 H HG22 . THR B 1 292 ? -11.58093 -2.68762  -40.16230 1.000 35.90362  ? 292 THR B HG22 1 
ATOM   8976 H HG23 . THR B 1 292 ? -11.06019 -2.45967  -41.63518 1.000 35.90362  ? 292 THR B HG23 1 
ATOM   8977 N N    . PRO B 1 293 ? -6.93843  -4.74546  -40.01154 1.000 30.68896  ? 293 PRO B N    1 
ATOM   8978 C CA   . PRO B 1 293 ? -5.52467  -4.67884  -39.61036 1.000 33.59267  ? 293 PRO B CA   1 
ATOM   8979 C C    . PRO B 1 293 ? -5.13342  -3.31558  -39.06650 1.000 31.45675  ? 293 PRO B C    1 
ATOM   8980 O O    . PRO B 1 293 ? -4.27059  -3.23501  -38.18361 1.000 32.70472  ? 293 PRO B O    1 
ATOM   8981 C CB   . PRO B 1 293 ? -4.77693  -5.02825  -40.90535 1.000 32.10475  ? 293 PRO B CB   1 
ATOM   8982 C CG   . PRO B 1 293 ? -5.76754  -5.84250  -41.69799 1.000 39.78847  ? 293 PRO B CG   1 
ATOM   8983 C CD   . PRO B 1 293 ? -7.10374  -5.22368  -41.39612 1.000 33.93347  ? 293 PRO B CD   1 
ATOM   8984 H HA   . PRO B 1 293 ? -5.32482  -5.35711  -38.94635 1.000 40.30498  ? 293 PRO B HA   1 
ATOM   8985 H HB2  . PRO B 1 293 ? -4.53278  -4.21728  -41.37823 1.000 38.51947  ? 293 PRO B HB2  1 
ATOM   8986 H HB3  . PRO B 1 293 ? -3.98210  -5.54569  -40.70183 1.000 38.51947  ? 293 PRO B HB3  1 
ATOM   8987 H HG2  . PRO B 1 293 ? -5.56322  -5.78311  -42.64436 1.000 47.73993  ? 293 PRO B HG2  1 
ATOM   8988 H HG3  . PRO B 1 293 ? -5.74076  -6.76846  -41.41027 1.000 47.73993  ? 293 PRO B HG3  1 
ATOM   8989 H HD2  . PRO B 1 293 ? -7.28833  -4.48592  -41.99823 1.000 40.71393  ? 293 PRO B HD2  1 
ATOM   8990 H HD3  . PRO B 1 293 ? -7.81242  -5.88355  -41.45294 1.000 40.71393  ? 293 PRO B HD3  1 
ATOM   8991 N N    . PHE B 1 294 ? -5.75195  -2.23699  -39.55548 1.000 30.58824  ? 294 PHE B N    1 
ATOM   8992 C CA   . PHE B 1 294 ? -5.49074  -0.91974  -38.98271 1.000 36.87178  ? 294 PHE B CA   1 
ATOM   8993 C C    . PHE B 1 294 ? -6.06573  -0.80534  -37.57341 1.000 38.76952  ? 294 PHE B C    1 
ATOM   8994 O O    . PHE B 1 294 ? -5.41807  -0.25102  -36.67823 1.000 38.34059  ? 294 PHE B O    1 
ATOM   8995 C CB   . PHE B 1 294 ? -6.06445  0.17665   -39.88387 1.000 41.25889  ? 294 PHE B CB   1 
ATOM   8996 C CG   . PHE B 1 294 ? -6.10520  1.53480   -39.23261 1.000 50.22568  ? 294 PHE B CG   1 
ATOM   8997 C CD1  . PHE B 1 294 ? -7.20796  1.92950   -38.48803 1.000 56.62480  ? 294 PHE B CD1  1 
ATOM   8998 C CD2  . PHE B 1 294 ? -5.04155  2.41328   -39.35913 1.000 59.54987  ? 294 PHE B CD2  1 
ATOM   8999 C CE1  . PHE B 1 294 ? -7.24913  3.17280   -37.88069 1.000 57.29021  ? 294 PHE B CE1  1 
ATOM   9000 C CE2  . PHE B 1 294 ? -5.07727  3.66045   -38.75512 1.000 62.90332  ? 294 PHE B CE2  1 
ATOM   9001 C CZ   . PHE B 1 294 ? -6.18336  4.03836   -38.01428 1.000 61.05463  ? 294 PHE B CZ   1 
ATOM   9002 H H    . PHE B 1 294 ? -6.31544  -2.24259  -40.20512 1.000 36.69966  ? 294 PHE B H    1 
ATOM   9003 H HA   . PHE B 1 294 ? -4.53066  -0.79150  -38.93071 1.000 44.23991  ? 294 PHE B HA   1 
ATOM   9004 H HB2  . PHE B 1 294 ? -5.51464  0.24599   -40.67998 1.000 49.50443  ? 294 PHE B HB2  1 
ATOM   9005 H HB3  . PHE B 1 294 ? -6.97234  -0.06268  -40.12749 1.000 49.50443  ? 294 PHE B HB3  1 
ATOM   9006 H HD1  . PHE B 1 294 ? -7.92972  1.35031   -38.39579 1.000 67.94353  ? 294 PHE B HD1  1 
ATOM   9007 H HD2  . PHE B 1 294 ? -4.29530  2.16355   -39.85476 1.000 71.45362  ? 294 PHE B HD2  1 
ATOM   9008 H HE1  . PHE B 1 294 ? -7.99388  3.42404   -37.38357 1.000 68.74202  ? 294 PHE B HE1  1 
ATOM   9009 H HE2  . PHE B 1 294 ? -4.35823  4.24295   -38.84771 1.000 75.47776  ? 294 PHE B HE2  1 
ATOM   9010 H HZ   . PHE B 1 294 ? -6.20811  4.87421   -37.60729 1.000 73.25933  ? 294 PHE B HZ   1 
ATOM   9011 N N    . ASP B 1 295 ? -7.28544  -1.31265  -37.36028 1.000 36.14971  ? 295 ASP B N    1 
ATOM   9012 C CA   . ASP B 1 295 ? -7.88336  -1.27172  -36.02834 1.000 33.56623  ? 295 ASP B CA   1 
ATOM   9013 C C    . ASP B 1 295 ? -6.97688  -1.93661  -35.00070 1.000 43.79058  ? 295 ASP B C    1 
ATOM   9014 O O    . ASP B 1 295 ? -6.78579  -1.41434  -33.89425 1.000 41.66682  ? 295 ASP B O    1 
ATOM   9015 C CB   . ASP B 1 295 ? -9.24632  -1.96615  -36.03682 1.000 35.61255  ? 295 ASP B CB   1 
ATOM   9016 C CG   . ASP B 1 295 ? -10.23100 -1.32019  -36.98665 1.000 41.88225  ? 295 ASP B CG   1 
ATOM   9017 O OD1  . ASP B 1 295 ? -9.94334  -0.21147  -37.49222 1.000 46.13831  ? 295 ASP B OD1  1 
ATOM   9018 O OD2  . ASP B 1 295 ? -11.29266 -1.93516  -37.23397 1.000 31.17593  ? 295 ASP B OD2  1 
ATOM   9019 H H    . ASP B 1 295 ? -7.77793  -1.67980  -37.96216 1.000 43.37342  ? 295 ASP B H    1 
ATOM   9020 H HA   . ASP B 1 295 ? -8.01273  -0.34332  -35.77886 1.000 40.27324  ? 295 ASP B HA   1 
ATOM   9021 H HB2  . ASP B 1 295 ? -9.12832  -2.88928  -36.31034 1.000 42.72883  ? 295 ASP B HB2  1 
ATOM   9022 H HB3  . ASP B 1 295 ? -9.62415  -1.93033  -35.14415 1.000 42.72883  ? 295 ASP B HB3  1 
ATOM   9023 N N    . VAL B 1 296 ? -6.42326  -3.10091  -35.34472 1.000 35.62190  ? 296 VAL B N    1 
ATOM   9024 C CA   . VAL B 1 296 ? -5.56160  -3.82337  -34.41212 1.000 42.18141  ? 296 VAL B CA   1 
ATOM   9025 C C    . VAL B 1 296 ? -4.32324  -2.99491  -34.08884 1.000 37.56265  ? 296 VAL B C    1 
ATOM   9026 O O    . VAL B 1 296 ? -3.94001  -2.84911  -32.92231 1.000 38.61904  ? 296 VAL B O    1 
ATOM   9027 C CB   . VAL B 1 296 ? -5.18914  -5.20498  -34.98292 1.000 39.20715  ? 296 VAL B CB   1 
ATOM   9028 C CG1  . VAL B 1 296 ? -4.22170  -5.92533  -34.05150 1.000 32.83228  ? 296 VAL B CG1  1 
ATOM   9029 C CG2  . VAL B 1 296 ? -6.44253  -6.04757  -35.19788 1.000 33.24928  ? 296 VAL B CG2  1 
ATOM   9030 H H    . VAL B 1 296 ? -6.53007  -3.48950  -36.10445 1.000 42.74005  ? 296 VAL B H    1 
ATOM   9031 H HA   . VAL B 1 296 ? -6.04962  -3.96547  -33.58596 1.000 50.61147  ? 296 VAL B HA   1 
ATOM   9032 H HB   . VAL B 1 296 ? -4.75198  -5.08091  -35.83989 1.000 47.04236  ? 296 VAL B HB   1 
ATOM   9033 H HG11 . VAL B 1 296 ? -4.47294  -5.74266  -33.13258 1.000 39.39251  ? 296 VAL B HG11 1 
ATOM   9034 H HG12 . VAL B 1 296 ? -4.26822  -6.87876  -34.22385 1.000 39.39251  ? 296 VAL B HG12 1 
ATOM   9035 H HG13 . VAL B 1 296 ? -3.32251  -5.60239  -34.21902 1.000 39.39251  ? 296 VAL B HG13 1 
ATOM   9036 H HG21 . VAL B 1 296 ? -6.19183  -6.88496  -35.61839 1.000 39.89291  ? 296 VAL B HG21 1 
ATOM   9037 H HG22 . VAL B 1 296 ? -6.85811  -6.22033  -34.33861 1.000 39.89291  ? 296 VAL B HG22 1 
ATOM   9038 H HG23 . VAL B 1 296 ? -7.05604  -5.56071  -35.77012 1.000 39.89291  ? 296 VAL B HG23 1 
ATOM   9039 N N    . VAL B 1 297 ? -3.68611  -2.42753  -35.11780 1.000 39.04419  ? 297 VAL B N    1 
ATOM   9040 C CA   . VAL B 1 297 ? -2.50072  -1.59975  -34.89895 1.000 44.13240  ? 297 VAL B CA   1 
ATOM   9041 C C    . VAL B 1 297 ? -2.83895  -0.40911  -34.01284 1.000 41.18341  ? 297 VAL B C    1 
ATOM   9042 O O    . VAL B 1 297 ? -2.09098  -0.06798  -33.08601 1.000 38.53978  ? 297 VAL B O    1 
ATOM   9043 C CB   . VAL B 1 297 ? -1.91444  -1.14193  -36.24886 1.000 42.75543  ? 297 VAL B CB   1 
ATOM   9044 C CG1  . VAL B 1 297 ? -0.92666  -0.00103  -36.04078 1.000 40.06367  ? 297 VAL B CG1  1 
ATOM   9045 C CG2  . VAL B 1 297 ? -1.25113  -2.30727  -36.95859 1.000 40.97829  ? 297 VAL B CG2  1 
ATOM   9046 H H    . VAL B 1 297 ? -3.91799  -2.50598  -35.94222 1.000 46.84680  ? 297 VAL B H    1 
ATOM   9047 H HA   . VAL B 1 297 ? -1.83307  -2.13539  -34.44262 1.000 52.95265  ? 297 VAL B HA   1 
ATOM   9048 H HB   . VAL B 1 297 ? -2.63362  -0.81619  -36.81240 1.000 51.30029  ? 297 VAL B HB   1 
ATOM   9049 H HG11 . VAL B 1 297 ? -0.39857  -0.18129  -35.24735 1.000 48.07018  ? 297 VAL B HG11 1 
ATOM   9050 H HG12 . VAL B 1 297 ? -0.34761  0.06078   -36.81652 1.000 48.07018  ? 297 VAL B HG12 1 
ATOM   9051 H HG13 . VAL B 1 297 ? -1.41948  0.82694   -35.92905 1.000 48.07018  ? 297 VAL B HG13 1 
ATOM   9052 H HG21 . VAL B 1 297 ? -1.15579  -3.04401  -36.33486 1.000 49.16772  ? 297 VAL B HG21 1 
ATOM   9053 H HG22 . VAL B 1 297 ? -1.80508  -2.57756  -37.70758 1.000 49.16772  ? 297 VAL B HG22 1 
ATOM   9054 H HG23 . VAL B 1 297 ? -0.37832  -2.02797  -37.27652 1.000 49.16772  ? 297 VAL B HG23 1 
ATOM   9055 N N    . ARG B 1 298 ? -3.96446  0.24952   -34.29027 1.000 40.29916  ? 298 ARG B N    1 
ATOM   9056 C CA   . ARG B 1 298 ? -4.38359  1.38688   -33.47891 1.000 42.10358  ? 298 ARG B CA   1 
ATOM   9057 C C    . ARG B 1 298 ? -4.53150  0.98825   -32.01523 1.000 43.37276  ? 298 ARG B C    1 
ATOM   9058 O O    . ARG B 1 298 ? -3.92408  1.59910   -31.12873 1.000 46.39918  ? 298 ARG B O    1 
ATOM   9059 C CB   . ARG B 1 298 ? -5.69566  1.95804   -34.02881 1.000 43.23021  ? 298 ARG B CB   1 
ATOM   9060 C CG   . ARG B 1 298 ? -6.35928  3.02236   -33.15553 1.000 59.74560  ? 298 ARG B CG   1 
ATOM   9061 C CD   . ARG B 1 298 ? -7.60075  3.62056   -33.82832 1.000 67.49759  ? 298 ARG B CD   1 
ATOM   9062 N NE   . ARG B 1 298 ? -8.74611  2.71252   -33.83979 1.000 81.14353  ? 298 ARG B NE   1 
ATOM   9063 C CZ   . ARG B 1 298 ? -9.74946  2.73856   -32.96830 1.000 63.79908  ? 298 ARG B CZ   1 
ATOM   9064 N NH1  . ARG B 1 298 ? -9.78298  3.60776   -31.97082 1.000 60.86669  ? 298 ARG B NH1  1 
ATOM   9065 N NH2  . ARG B 1 298 ? -10.74939 1.87279   -33.10493 1.000 42.14024  ? 298 ARG B NH2  1 
ATOM   9066 H H    . ARG B 1 298 ? -4.49782  0.05874   -34.93736 1.000 48.35277  ? 298 ARG B H    1 
ATOM   9067 H HA   . ARG B 1 298 ? -3.70866  2.08168   -33.53017 1.000 50.51807  ? 298 ARG B HA   1 
ATOM   9068 H HB2  . ARG B 1 298 ? -5.51557  2.36231   -34.89196 1.000 51.87003  ? 298 ARG B HB2  1 
ATOM   9069 H HB3  . ARG B 1 298 ? -6.32833  1.22964   -34.12914 1.000 51.87003  ? 298 ARG B HB3  1 
ATOM   9070 H HG2  . ARG B 1 298 ? -6.63285  2.62188   -32.31549 1.000 71.68849  ? 298 ARG B HG2  1 
ATOM   9071 H HG3  . ARG B 1 298 ? -5.72801  3.74018   -32.99083 1.000 71.68849  ? 298 ARG B HG3  1 
ATOM   9072 H HD2  . ARG B 1 298 ? -7.86187  4.42269   -33.34947 1.000 80.99089  ? 298 ARG B HD2  1 
ATOM   9073 H HD3  . ARG B 1 298 ? -7.38502  3.83889   -34.74847 1.000 80.99089  ? 298 ARG B HD3  1 
ATOM   9074 H HE   . ARG B 1 298 ? -8.77291  2.11535   -34.45808 1.000 97.36601  ? 298 ARG B HE   1 
ATOM   9075 H HH11 . ARG B 1 298 ? -9.14446  4.17562   -31.87366 1.000 73.03380  ? 298 ARG B HH11 1 
ATOM   9076 H HH12 . ARG B 1 298 ? -10.44327 3.60471   -31.41982 1.000 73.03380  ? 298 ARG B HH12 1 
ATOM   9077 H HH21 . ARG B 1 298 ? -10.74159 1.30534   -33.75110 1.000 50.56206  ? 298 ARG B HH21 1 
ATOM   9078 H HH22 . ARG B 1 298 ? -11.40390 1.88029   -32.54712 1.000 50.56206  ? 298 ARG B HH22 1 
ATOM   9079 N N    . GLN B 1 299 ? -5.32500  -0.04933  -31.74209 1.000 42.29014  ? 299 GLN B N    1 
ATOM   9080 C CA   . GLN B 1 299 ? -5.62672  -0.38960  -30.35599 1.000 45.06330  ? 299 GLN B CA   1 
ATOM   9081 C C    . GLN B 1 299 ? -4.39600  -0.91234  -29.62763 1.000 48.04761  ? 299 GLN B C    1 
ATOM   9082 O O    . GLN B 1 299 ? -4.20104  -0.62120  -28.44197 1.000 52.40226  ? 299 GLN B O    1 
ATOM   9083 C CB   . GLN B 1 299 ? -6.75201  -1.42201  -30.29183 1.000 36.43346  ? 299 GLN B CB   1 
ATOM   9084 C CG   . GLN B 1 299 ? -7.26582  -1.64000  -28.87486 1.000 43.60332  ? 299 GLN B CG   1 
ATOM   9085 C CD   . GLN B 1 299 ? -8.50442  -2.52505  -28.78267 1.000 38.57745  ? 299 GLN B CD   1 
ATOM   9086 O OE1  . GLN B 1 299 ? -8.79145  -3.06854  -27.71905 1.000 34.73330  ? 299 GLN B OE1  1 
ATOM   9087 N NE2  . GLN B 1 299 ? -9.24365  -2.66542  -29.88458 1.000 33.44105  ? 299 GLN B NE2  1 
ATOM   9088 H H    . GLN B 1 299 ? -5.69225  -0.55973  -32.32879 1.000 50.74194  ? 299 GLN B H    1 
ATOM   9089 H HA   . GLN B 1 299 ? -5.92796  0.41550   -29.90657 1.000 54.06973  ? 299 GLN B HA   1 
ATOM   9090 H HB2  . GLN B 1 299 ? -7.49349  -1.11601  -30.83723 1.000 43.71393  ? 299 GLN B HB2  1 
ATOM   9091 H HB3  . GLN B 1 299 ? -6.42214  -2.27064  -30.62638 1.000 43.71393  ? 299 GLN B HB3  1 
ATOM   9092 H HG2  . GLN B 1 299 ? -6.56525  -2.06137  -28.35279 1.000 52.31775  ? 299 GLN B HG2  1 
ATOM   9093 H HG3  . GLN B 1 299 ? -7.49246  -0.77823  -28.49160 1.000 52.31775  ? 299 GLN B HG3  1 
ATOM   9094 H HE21 . GLN B 1 299 ? -9.01463  -2.26430  -30.61001 1.000 40.12303  ? 299 GLN B HE21 1 
ATOM   9095 H HE22 . GLN B 1 299 ? -9.94913  -3.15702  -29.86937 1.000 40.12303  ? 299 GLN B HE22 1 
ATOM   9096 N N    . CYS B 1 300 ? -3.55878  -1.68472  -30.31371 1.000 48.35846  ? 300 CYS B N    1 
ATOM   9097 C CA   . CYS B 1 300 ? -2.39615  -2.30502  -29.69433 1.000 50.85114  ? 300 CYS B CA   1 
ATOM   9098 C C    . CYS B 1 300 ? -1.16064  -1.41084  -29.69674 1.000 52.78072  ? 300 CYS B C    1 
ATOM   9099 O O    . CYS B 1 300 ? -0.13203  -1.80821  -29.14049 1.000 52.24542  ? 300 CYS B O    1 
ATOM   9100 C CB   . CYS B 1 300 ? -2.07832  -3.63032  -30.39588 1.000 49.78564  ? 300 CYS B CB   1 
ATOM   9101 S SG   . CYS B 1 300 ? -3.36383  -4.89224  -30.19500 1.000 51.77832  ? 300 CYS B SG   1 
ATOM   9102 H H    . CYS B 1 300 ? -3.64550  -1.86575  -31.14996 1.000 58.02393  ? 300 CYS B H    1 
ATOM   9103 H HA   . CYS B 1 300 ? -2.60815  -2.49841  -28.76774 1.000 61.01514  ? 300 CYS B HA   1 
ATOM   9104 H HB2  . CYS B 1 300 ? -1.97405  -3.46273  -31.34558 1.000 59.73654  ? 300 CYS B HB2  1 
ATOM   9105 H HB3  . CYS B 1 300 ? -1.25397  -3.98676  -30.02942 1.000 59.73654  ? 300 CYS B HB3  1 
ATOM   9106 H HG   . CYS B 1 300 ? -3.49362  -5.13526  -29.02706 1.000 62.12775  ? 300 CYS B HG   1 
ATOM   9107 N N    . SER B 1 301 ? -1.22902  -0.22073  -30.30207 1.000 60.89159  ? 301 SER B N    1 
ATOM   9108 C CA   . SER B 1 301 ? -0.13459  0.73948   -30.23672 1.000 56.65699  ? 301 SER B CA   1 
ATOM   9109 C C    . SER B 1 301 ? -0.60322  2.15190   -29.90453 1.000 63.33491  ? 301 SER B C    1 
ATOM   9110 O O    . SER B 1 301 ? 0.22409   3.06977   -29.88075 1.000 68.61610  ? 301 SER B O    1 
ATOM   9111 C CB   . SER B 1 301 ? 0.65591   0.75448   -31.55596 1.000 63.83233  ? 301 SER B CB   1 
ATOM   9112 O OG   . SER B 1 301 ? 1.19841   -0.52654  -31.84152 1.000 58.17781  ? 301 SER B OG   1 
ATOM   9113 H H    . SER B 1 301 ? -1.90514  0.05136   -30.75861 1.000 73.06367  ? 301 SER B H    1 
ATOM   9114 H HA   . SER B 1 301 ? 0.48169   0.46131   -29.54122 1.000 67.98216  ? 301 SER B HA   1 
ATOM   9115 H HB2  . SER B 1 301 ? 0.06019   1.01183   -32.27692 1.000 76.59257  ? 301 SER B HB2  1 
ATOM   9116 H HB3  . SER B 1 301 ? 1.38144   1.39391   -31.48086 1.000 76.59257  ? 301 SER B HB3  1 
ATOM   9117 H HG   . SER B 1 301 ? 0.61389   -1.01306  -32.19822 1.000 69.80714  ? 301 SER B HG   1 
ATOM   9118 N N    . GLY B 1 302 ? -1.89922  2.35470   -29.66920 1.000 73.72744  ? 302 GLY B N    1 
ATOM   9119 C CA   . GLY B 1 302 ? -2.39391  3.55401   -29.01673 1.000 69.36398  ? 302 GLY B CA   1 
ATOM   9120 C C    . GLY B 1 302 ? -2.41716  4.83376   -29.82914 1.000 74.03441  ? 302 GLY B C    1 
ATOM   9121 O O    . GLY B 1 302 ? -1.93157  5.86831   -29.36174 1.000 70.72834  ? 302 GLY B O    1 
ATOM   9122 H H    . GLY B 1 302 ? -2.52010  1.79958   -29.88358 1.000 88.46670  ? 302 GLY B H    1 
ATOM   9123 H HA2  . GLY B 1 302 ? -3.30418  3.38517   -28.72725 1.000 83.23054  ? 302 GLY B HA2  1 
ATOM   9124 H HA3  . GLY B 1 302 ? -1.84092  3.72246   -28.23781 1.000 83.23054  ? 302 GLY B HA3  1 
ATOM   9125 N N    . VAL B 1 303 ? -2.99149  4.79531   -31.02752 1.000 62.20889  ? 303 VAL B N    1 
ATOM   9126 C CA   . VAL B 1 303 ? -3.14577  6.00497   -31.83338 1.000 78.37207  ? 303 VAL B CA   1 
ATOM   9127 C C    . VAL B 1 303 ? -4.26378  6.86923   -31.25053 1.000 77.47431  ? 303 VAL B C    1 
ATOM   9128 O O    . VAL B 1 303 ? -5.06475  6.40629   -30.43882 1.000 79.79858  ? 303 VAL B O    1 
ATOM   9129 C CB   . VAL B 1 303 ? -3.41347  5.65953   -33.31944 1.000 75.66381  ? 303 VAL B CB   1 
ATOM   9130 C CG1  . VAL B 1 303 ? -4.60409  6.44334   -33.86997 1.000 71.67615  ? 303 VAL B CG1  1 
ATOM   9131 C CG2  . VAL B 1 303 ? -2.16651  5.93307   -34.15278 1.000 73.40037  ? 303 VAL B CG2  1 
ATOM   9132 H H    . VAL B 1 303 ? -3.30008  4.08261   -31.39689 1.000 74.64444  ? 303 VAL B H    1 
ATOM   9133 H HA   . VAL B 1 303 ? -2.32206  6.51649   -31.80623 1.000 94.04026  ? 303 VAL B HA   1 
ATOM   9134 H HB   . VAL B 1 303 ? -3.63231  4.71649   -33.38016 1.000 90.79034  ? 303 VAL B HB   1 
ATOM   9135 H HG11 . VAL B 1 303 ? -4.69822  6.25147   -34.81613 1.000 86.00515  ? 303 VAL B HG11 1 
ATOM   9136 H HG12 . VAL B 1 303 ? -5.40629  6.17317   -33.39627 1.000 86.00515  ? 303 VAL B HG12 1 
ATOM   9137 H HG13 . VAL B 1 303 ? -4.44595  7.39133   -33.73883 1.000 86.00515  ? 303 VAL B HG13 1 
ATOM   9138 H HG21 . VAL B 1 303 ? -2.31666  5.61921   -35.05823 1.000 88.07421  ? 303 VAL B HG21 1 
ATOM   9139 H HG22 . VAL B 1 303 ? -1.99324  6.88746   -34.15798 1.000 88.07421  ? 303 VAL B HG22 1 
ATOM   9140 H HG23 . VAL B 1 303 ? -1.41469  5.46254   -33.76000 1.000 88.07421  ? 303 VAL B HG23 1 
HETATM 9141 C C8   . 4WI C 2 .   ? -2.02664  -0.34736  -18.17639 1.000 45.02505  ? 401 4WI A C8   1 
HETATM 9142 C C3   . 4WI C 2 .   ? -0.56701  4.12745   -16.71309 1.000 44.75180  ? 401 4WI A C3   1 
HETATM 9143 C C1   . 4WI C 2 .   ? 1.05015   1.60907   -14.86676 1.000 44.61817  ? 401 4WI A C1   1 
HETATM 9144 C C13  . 4WI C 2 .   ? 1.09709   -1.19200  -13.72567 1.000 51.41181  ? 401 4WI A C13  1 
HETATM 9145 C C21  . 4WI C 2 .   ? 1.15999   -3.88176  -11.57341 1.000 48.03861  ? 401 4WI A C21  1 
HETATM 9146 C C6   . 4WI C 2 .   ? 0.38196   0.00224   -17.99643 1.000 53.01408  ? 401 4WI A C6   1 
HETATM 9147 C C7   . 4WI C 2 .   ? 0.07280   -1.10167  -18.99733 1.000 49.75806  ? 401 4WI A C7   1 
HETATM 9148 C C10  . 4WI C 2 .   ? 2.86098   0.12261   -12.47682 1.000 46.09383  ? 401 4WI A C10  1 
HETATM 9149 C C5   . 4WI C 2 .   ? -0.96207  0.41487   -17.39988 1.000 43.21562  ? 401 4WI A C5   1 
HETATM 9150 C C9   . 4WI C 2 .   ? 0.94062   1.24764   -13.41437 1.000 46.41478  ? 401 4WI A C9   1 
HETATM 9151 C C11  . 4WI C 2 .   ? 2.85310   1.56275   -11.92393 1.000 48.51433  ? 401 4WI A C11  1 
HETATM 9152 C C12  . 4WI C 2 .   ? 1.66850   2.26862   -12.52625 1.000 52.70530  ? 401 4WI A C12  1 
HETATM 9153 C C18  . 4WI C 2 .   ? 1.61073   1.83115   -11.06315 1.000 48.03445  ? 401 4WI A C18  1 
HETATM 9154 C C19  . 4WI C 2 .   ? 1.68106   2.93245   -10.04524 1.000 45.50391  ? 401 4WI A C19  1 
HETATM 9155 C C20  . 4WI C 2 .   ? 0.73134   0.73560   -10.51494 1.000 46.69088  ? 401 4WI A C20  1 
HETATM 9156 C C16  . 4WI C 2 .   ? 1.24094   -3.33386  -15.76875 1.000 53.90339  ? 401 4WI A C16  1 
HETATM 9157 C C17  . 4WI C 2 .   ? 3.13798   -4.32055  -14.45227 1.000 43.34806  ? 401 4WI A C17  1 
HETATM 9158 C C23  . 4WI C 2 .   ? 3.34885   -1.99594  -15.40967 1.000 48.14960  ? 401 4WI A C23  1 
HETATM 9159 C C4   . 4WI C 2 .   ? -1.22296  1.89602   -17.47522 1.000 50.51128  ? 401 4WI A C4   1 
HETATM 9160 C C2   . 4WI C 2 .   ? -0.17376  2.67855   -16.73494 1.000 55.65344  ? 401 4WI A C2   1 
HETATM 9161 C C14  . 4WI C 2 .   ? 1.87773   -2.45886  -13.48557 1.000 47.73624  ? 401 4WI A C14  1 
HETATM 9162 C C22  . 4WI C 2 .   ? 0.05445   -4.79659  -11.12151 1.000 64.15424  ? 401 4WI A C22  1 
HETATM 9163 C C15  . 4WI C 2 .   ? 2.38903   -3.02528  -14.79021 1.000 46.21228  ? 401 4WI A C15  1 
HETATM 9164 N N5   . 4WI C 2 .   ? 0.31050   5.10478   -17.13383 1.000 61.07164  ? 401 4WI A N5   1 
HETATM 9165 N N2   . 4WI C 2 .   ? -1.38418  -1.15204  -19.03050 1.000 45.52846  ? 401 4WI A N2   1 
HETATM 9166 N N3   . 4WI C 2 .   ? 1.60816   -0.03858  -13.22482 1.000 49.66514  ? 401 4WI A N3   1 
HETATM 9167 N N1   . 4WI C 2 .   ? -0.05188  2.16416   -15.37210 1.000 44.55746  ? 401 4WI A N1   1 
HETATM 9168 N N4   . 4WI C 2 .   ? 0.97280   -3.38397  -12.79911 1.000 43.35122  ? 401 4WI A N4   1 
HETATM 9169 O O1   . 4WI C 2 .   ? -3.23965  -0.24438  -18.04335 1.000 43.11706  ? 401 4WI A O1   1 
HETATM 9170 O O2   . 4WI C 2 .   ? 2.09442   1.52534   -15.50344 1.000 49.83822  ? 401 4WI A O2   1 
HETATM 9171 O O3   . 4WI C 2 .   ? 0.02640   -1.20779  -14.34374 1.000 48.61262  ? 401 4WI A O3   1 
HETATM 9172 O O4   . 4WI C 2 .   ? 2.14478   -3.60558  -10.90167 1.000 47.98551  ? 401 4WI A O4   1 
HETATM 9173 F F1   . 4WI C 2 .   ? -1.11681  -4.23777  -11.43496 1.000 70.17978  ? 401 4WI A F1   1 
HETATM 9174 F F2   . 4WI C 2 .   ? 0.13103   -4.94667  -9.79793  1.000 54.36251  ? 401 4WI A F2   1 
HETATM 9175 F F3   . 4WI C 2 .   ? 0.18497   -5.97864  -11.72079 1.000 63.75032  ? 401 4WI A F3   1 
HETATM 9176 H H5   . 4WI C 2 .   ? 0.83872   0.84990   -18.50725 1.000 63.61067  ? 401 4WI A H5   1 
HETATM 9177 H H6   . 4WI C 2 .   ? 1.03604   -0.37935  -17.21243 1.000 63.61067  ? 401 4WI A H6   1 
HETATM 9178 H H7   . 4WI C 2 .   ? 0.46439   -0.84166  -19.97744 1.000 59.70344  ? 401 4WI A H7   1 
HETATM 9179 H H8   . 4WI C 2 .   ? 0.47590   -2.04922  -18.64915 1.000 59.70344  ? 401 4WI A H8   1 
HETATM 9180 H H11  . 4WI C 2 .   ? 2.76692   -0.09142  -11.41218 1.000 55.30637  ? 401 4WI A H11  1 
HETATM 9181 H H12  . 4WI C 2 .   ? 3.67243   0.54875   -13.06677 1.000 55.30637  ? 401 4WI A H12  1 
HETATM 9182 H H10  . 4WI C 2 .   ? -0.08574  1.20281   -13.05013 1.000 55.69151  ? 401 4WI A H10  1 
HETATM 9183 H H14  . 4WI C 2 .   ? 1.58135   3.35175   -12.61186 1.000 63.24014  ? 401 4WI A H14  1 
HETATM 9184 H H23  . 4WI C 2 .   ? 0.67899   3.29531   -9.83133  1.000 54.59847  ? 401 4WI A H23  1 
HETATM 9185 H H24  . 4WI C 2 .   ? 2.28485   3.74892   -10.43304 1.000 54.59847  ? 401 4WI A H24  1 
HETATM 9186 H H25  . 4WI C 2 .   ? 2.13052   2.55479   -9.13041  1.000 54.59847  ? 401 4WI A H25  1 
HETATM 9187 H H26  . 4WI C 2 .   ? 0.32481   0.14978   -11.34198 1.000 56.02282  ? 401 4WI A H26  1 
HETATM 9188 H H27  . 4WI C 2 .   ? 1.32274   0.08836   -9.86393  1.000 56.02282  ? 401 4WI A H27  1 
HETATM 9189 H H28  . 4WI C 2 .   ? -0.08682  1.17969   -9.94409  1.000 56.02282  ? 401 4WI A H28  1 
HETATM 9190 H H17  . 4WI C 2 .   ? 1.59167   -4.02681  -16.53068 1.000 64.67784  ? 401 4WI A H17  1 
HETATM 9191 H H19  . 4WI C 2 .   ? 0.91031   -2.41103  -16.24079 1.000 64.67784  ? 401 4WI A H19  1 
HETATM 9192 H H18  . 4WI C 2 .   ? 0.41203   -3.78111  -15.22411 1.000 64.67784  ? 401 4WI A H18  1 
HETATM 9193 H H20  . 4WI C 2 .   ? 3.57593   -4.73497  -15.35792 1.000 52.01144  ? 401 4WI A H20  1 
HETATM 9194 H H21  . 4WI C 2 .   ? 3.92715   -4.10821  -13.73404 1.000 52.01144  ? 401 4WI A H21  1 
HETATM 9195 H H22  . 4WI C 2 .   ? 2.44442   -5.04124  -14.02411 1.000 52.01144  ? 401 4WI A H22  1 
HETATM 9196 H H29  . 4WI C 2 .   ? 2.77761   -1.26240  -15.97862 1.000 57.77329  ? 401 4WI A H29  1 
HETATM 9197 H H30  . 4WI C 2 .   ? 3.90106   -1.49071  -14.61727 1.000 57.77329  ? 401 4WI A H30  1 
HETATM 9198 H H31  . 4WI C 2 .   ? 4.04888   -2.50439  -16.07265 1.000 57.77329  ? 401 4WI A H31  1 
HETATM 9199 H H2   . 4WI C 2 .   ? -1.22198  2.20495   -18.52052 1.000 60.60731  ? 401 4WI A H2   1 
HETATM 9200 H H3   . 4WI C 2 .   ? -2.19761  2.10862   -17.03595 1.000 60.60731  ? 401 4WI A H3   1 
HETATM 9201 H H32  . 4WI C 2 .   ? 0.78696   2.57639   -17.23527 1.000 66.77790  ? 401 4WI A H32  1 
HETATM 9202 H H15  . 4WI C 2 .   ? 2.76084   -2.27280  -12.87434 1.000 57.27726  ? 401 4WI A H15  1 
HETATM 9203 H H9   . 4WI C 2 .   ? -1.87860  -1.75941  -19.66191 1.000 54.62792  ? 401 4WI A H9   1 
HETATM 9204 H H1   . 4WI C 2 .   ? -0.85092  1.60327   -15.14638 1.000 53.46272  ? 401 4WI A H1   1 
HETATM 9205 H H16  . 4WI C 2 .   ? 0.14206   -3.66833  -13.29007 1.000 52.01524  ? 401 4WI A H16  1 
HETATM 9206 C C8   . 4WI D 2 .   ? -34.70410 -0.07989  -38.57288 1.000 42.19233  ? 401 4WI B C8   1 
HETATM 9207 C C3   . 4WI D 2 .   ? -36.42666 4.29126   -40.09995 1.000 45.48030  ? 401 4WI B C3   1 
HETATM 9208 C C1   . 4WI D 2 .   ? -37.77050 1.92269   -42.07703 1.000 50.24515  ? 401 4WI B C1   1 
HETATM 9209 C C13  . 4WI D 2 .   ? -37.75486 -0.77919  -43.29858 1.000 44.40926  ? 401 4WI B C13  1 
HETATM 9210 C C21  . 4WI D 2 .   ? -37.96285 -3.48272  -45.52091 1.000 50.10939  ? 401 4WI B C21  1 
HETATM 9211 C C6   . 4WI D 2 .   ? -37.12800 0.20035   -38.54269 1.000 52.76271  ? 401 4WI B C6   1 
HETATM 9212 C C7   . 4WI D 2 .   ? -36.70792 -0.94416  -37.63628 1.000 51.61758  ? 401 4WI B C7   1 
HETATM 9213 C C10  . 4WI D 2 .   ? -39.44744 0.55925   -44.61302 1.000 41.70450  ? 401 4WI B C10  1 
HETATM 9214 C C5   . 4WI D 2 .   ? -35.85708 0.64486   -39.25606 1.000 40.66350  ? 401 4WI B C5   1 
HETATM 9215 C C9   . 4WI D 2 .   ? -37.59512 1.67894   -43.55112 1.000 41.75868  ? 401 4WI B C9   1 
HETATM 9216 C C11  . 4WI D 2 .   ? -39.50819 2.04658   -45.00223 1.000 45.81216  ? 401 4WI B C11  1 
HETATM 9217 C C12  . 4WI D 2 .   ? -38.35068 2.75256   -44.35327 1.000 51.61150  ? 401 4WI B C12  1 
HETATM 9218 C C18  . 4WI D 2 .   ? -38.29937 2.45659   -45.85113 1.000 48.35801  ? 401 4WI B C18  1 
HETATM 9219 C C19  . 4WI D 2 .   ? -38.50247 3.60885   -46.79112 1.000 40.08182  ? 401 4WI B C19  1 
HETATM 9220 C C20  . 4WI D 2 .   ? -37.30130 1.51112   -46.46662 1.000 45.70831  ? 401 4WI B C20  1 
HETATM 9221 C C16  . 4WI D 2 .   ? -37.92178 -2.93394  -41.33104 1.000 50.47897  ? 401 4WI B C16  1 
HETATM 9222 C C17  . 4WI D 2 .   ? -39.84562 -3.88837  -42.65658 1.000 40.31929  ? 401 4WI B C17  1 
HETATM 9223 C C23  . 4WI D 2 .   ? -40.02416 -1.58256  -41.66941 1.000 45.65656  ? 401 4WI B C23  1 
HETATM 9224 C C4   . 4WI D 2 .   ? -35.67120 2.13386   -39.19869 1.000 52.87341  ? 401 4WI B C4   1 
HETATM 9225 C C2   . 4WI D 2 .   ? -36.70167 2.81681   -40.05346 1.000 51.27463  ? 401 4WI B C2   1 
HETATM 9226 C C14  . 4WI D 2 .   ? -38.54128 -2.03251  -43.59900 1.000 45.92931  ? 401 4WI B C14  1 
HETATM 9227 C C22  . 4WI D 2 .   ? -36.90507 -4.41804  -46.03927 1.000 64.94739  ? 401 4WI B C22  1 
HETATM 9228 C C15  . 4WI D 2 .   ? -39.07163 -2.61156  -42.30366 1.000 46.28395  ? 401 4WI B C15  1 
HETATM 9229 N N5   . 4WI D 2 .   ? -36.33301 5.01978   -38.93513 1.000 48.85048  ? 401 4WI B N5   1 
HETATM 9230 N N2   . 4WI D 2 .   ? -35.25083 -0.92824  -37.70127 1.000 48.01208  ? 401 4WI B N2   1 
HETATM 9231 N N3   . 4WI D 2 .   ? -38.23353 0.38894   -43.80690 1.000 43.33558  ? 401 4WI B N3   1 
HETATM 9232 N N1   . 4WI D 2 .   ? -36.67303 2.27835   -41.41293 1.000 41.96884  ? 401 4WI B N1   1 
HETATM 9233 N N4   . 4WI D 2 .   ? -37.68348 -2.97802  -44.31643 1.000 48.28491  ? 401 4WI B N4   1 
HETATM 9234 O O1   . 4WI D 2 .   ? -33.50618 0.07444   -38.77872 1.000 43.24558  ? 401 4WI B O1   1 
HETATM 9235 O O2   . 4WI D 2 .   ? -38.83643 1.73338   -41.49370 1.000 52.78630  ? 401 4WI B O2   1 
HETATM 9236 O O3   . 4WI D 2 .   ? -36.72259 -0.81315  -42.61817 1.000 43.94720  ? 401 4WI B O3   1 
HETATM 9237 O O4   . 4WI D 2 .   ? -38.99214 -3.19183  -46.12130 1.000 44.27265  ? 401 4WI B O4   1 
HETATM 9238 F F1   . 4WI D 2 .   ? -35.75396 -4.17009  -45.41107 1.000 58.80229  ? 401 4WI B F1   1 
HETATM 9239 F F2   . 4WI D 2 .   ? -36.75548 -4.21440  -47.35085 1.000 59.29224  ? 401 4WI B F2   1 
HETATM 9240 F F3   . 4WI D 2 .   ? -37.28565 -5.67332  -45.81811 1.000 65.60113  ? 401 4WI B F3   1 
HETATM 9241 H H5   . 4WI D 2 .   ? -37.86125 -0.14827  -39.26846 1.000 63.30902  ? 401 4WI B H5   1 
HETATM 9242 H H6   . 4WI D 2 .   ? -37.52848 1.01984   -37.94774 1.000 63.30902  ? 401 4WI B H6   1 
HETATM 9243 H H7   . 4WI D 2 .   ? -37.09296 -1.88797  -38.01668 1.000 61.93486  ? 401 4WI B H7   1 
HETATM 9244 H H8   . 4WI D 2 .   ? -37.04285 -0.76138  -36.61738 1.000 61.93486  ? 401 4WI B H8   1 
HETATM 9245 H H11  . 4WI D 2 .   ? -40.31983 0.86454   -44.03335 1.000 50.03917  ? 401 4WI B H11  1 
HETATM 9246 H H12  . 4WI D 2 .   ? -39.27632 0.47439   -45.68717 1.000 50.03917  ? 401 4WI B H12  1 
HETATM 9247 H H10  . 4WI D 2 .   ? -36.56996 1.68995   -43.92421 1.000 50.10419  ? 401 4WI B H10  1 
HETATM 9248 H H14  . 4WI D 2 .   ? -38.29036 3.82735   -44.18213 1.000 61.92757  ? 401 4WI B H14  1 
HETATM 9249 H H23  . 4WI D 2 .   ? -39.05440 4.39827   -46.28521 1.000 48.09196  ? 401 4WI B H23  1 
HETATM 9250 H H24  . 4WI D 2 .   ? -39.06491 3.27456   -47.66040 1.000 48.09196  ? 401 4WI B H24  1 
HETATM 9251 H H25  . 4WI D 2 .   ? -37.53582 3.99187   -47.11149 1.000 48.09196  ? 401 4WI B H25  1 
HETATM 9252 H H26  . 4WI D 2 .   ? -37.08898 0.70127   -45.76554 1.000 54.84374  ? 401 4WI B H26  1 
HETATM 9253 H H27  . 4WI D 2 .   ? -37.71481 1.09727   -47.38868 1.000 54.84374  ? 401 4WI B H27  1 
HETATM 9254 H H28  . 4WI D 2 .   ? -36.37944 2.05215   -46.69006 1.000 54.84374  ? 401 4WI B H28  1 
HETATM 9255 H H17  . 4WI D 2 .   ? -37.81951 -2.12528  -40.61188 1.000 60.56854  ? 401 4WI B H17  1 
HETATM 9256 H H19  . 4WI D 2 .   ? -36.99575 -3.04264  -41.88982 1.000 60.56854  ? 401 4WI B H19  1 
HETATM 9257 H H18  . 4WI D 2 .   ? -38.14099 -3.86073  -40.80705 1.000 60.56854  ? 401 4WI B H18  1 
HETATM 9258 H H20  . 4WI D 2 .   ? -40.63978 -3.64876  -43.36060 1.000 48.37692  ? 401 4WI B H20  1 
HETATM 9259 H H21  . 4WI D 2 .   ? -39.16823 -4.61091  -43.10694 1.000 48.37692  ? 401 4WI B H21  1 
HETATM 9260 H H22  . 4WI D 2 .   ? -40.27849 -4.31217  -41.75284 1.000 48.37692  ? 401 4WI B H22  1 
HETATM 9261 H H29  . 4WI D 2 .   ? -39.44666 -0.74301  -41.27964 1.000 54.78165  ? 401 4WI B H29  1 
HETATM 9262 H H30  . 4WI D 2 .   ? -40.57741 -2.05177  -40.85453 1.000 54.78165  ? 401 4WI B H30  1 
HETATM 9263 H H31  . 4WI D 2 .   ? -40.72531 -1.22168  -42.42336 1.000 54.78165  ? 401 4WI B H31  1 
HETATM 9264 H H2   . 4WI D 2 .   ? -34.67678 2.38813   -39.56255 1.000 63.44186  ? 401 4WI B H2   1 
HETATM 9265 H H3   . 4WI D 2 .   ? -35.77733 2.47182   -38.16891 1.000 63.44186  ? 401 4WI B H3   1 
HETATM 9266 H H32  . 4WI D 2 .   ? -37.68324 2.63960   -39.61888 1.000 61.52333  ? 401 4WI B H32  1 
HETATM 9267 H H15  . 4WI D 2 .   ? -39.39526 -1.80685  -44.23596 1.000 55.10895  ? 401 4WI B H15  1 
HETATM 9268 H H9   . 4WI D 2 .   ? -34.68884 -1.52507  -37.11990 1.000 57.60827  ? 401 4WI B H9   1 
HETATM 9269 H H1   . 4WI D 2 .   ? -36.06527 2.82190   -41.99704 1.000 50.35638  ? 401 4WI B H1   1 
HETATM 9270 H H16  . 4WI D 2 .   ? -36.82745 -3.26703  -43.87402 1.000 57.93566  ? 401 4WI B H16  1 
HETATM 9271 O O    . HOH E 3 .   ? -10.83943 -9.85655  -5.71740  1.000 43.28817  ? 501 HOH A O    1 
HETATM 9272 O O    . HOH E 3 .   ? -0.80610  9.28346   -21.24108 1.000 41.92442  ? 502 HOH A O    1 
HETATM 9273 O O    . HOH E 3 .   ? -7.88147  33.06877  -14.69947 1.000 64.87145  ? 503 HOH A O    1 
HETATM 9274 O O    . HOH E 3 .   ? -20.24621 -22.91663 -32.56037 1.000 46.17956  ? 504 HOH A O    1 
HETATM 9275 O O    . HOH E 3 .   ? -18.28025 18.57315  -21.85688 1.000 43.95695  ? 505 HOH A O    1 
HETATM 9276 O O    . HOH E 3 .   ? -7.52994  14.02910  1.30660   1.000 47.35466  ? 506 HOH A O    1 
HETATM 9277 O O    . HOH E 3 .   ? -23.67886 -3.17961  -21.44259 1.000 35.67666  ? 507 HOH A O    1 
HETATM 9278 O O    . HOH E 3 .   ? -6.74772  1.87608   -25.13758 1.000 36.90396  ? 508 HOH A O    1 
HETATM 9279 O O    . HOH E 3 .   ? -7.73774  2.50482   -2.47814  1.000 37.20821  ? 509 HOH A O    1 
HETATM 9280 O O    . HOH E 3 .   ? 0.14155   -7.89327  -14.05605 1.000 53.24193  ? 510 HOH A O    1 
HETATM 9281 O O    . HOH E 3 .   ? -3.19224  1.67296   -2.54938  1.000 40.74443  ? 511 HOH A O    1 
HETATM 9282 O O    . HOH E 3 .   ? -25.25551 -9.84096  -20.20038 1.000 39.98428  ? 512 HOH A O    1 
HETATM 9283 O O    . HOH E 3 .   ? -10.75641 -10.87394 -13.81751 1.000 48.55694  ? 513 HOH A O    1 
HETATM 9284 O O    . HOH E 3 .   ? -24.43459 -1.93586  -24.00631 1.000 34.15460  ? 514 HOH A O    1 
HETATM 9285 O O    . HOH E 3 .   ? -20.76400 -25.09764 -27.48079 1.000 54.71005  ? 515 HOH A O    1 
HETATM 9286 O O    . HOH E 3 .   ? 12.70321  8.94001   -5.07890  1.000 56.14033  ? 516 HOH A O    1 
HETATM 9287 O O    . HOH E 3 .   ? -18.73218 -9.66624  -5.83849  1.000 42.67865  ? 517 HOH A O    1 
HETATM 9288 O O    . HOH E 3 .   ? -30.17613 -2.78209  -14.28796 1.000 34.91123  ? 518 HOH A O    1 
HETATM 9289 O O    . HOH E 3 .   ? -27.36779 -1.58276  -24.03714 1.000 46.19743  ? 519 HOH A O    1 
HETATM 9290 O O    . HOH E 3 .   ? 1.72944   -1.03105  -22.34047 1.000 41.23972  ? 520 HOH A O    1 
HETATM 9291 O O    . HOH E 3 .   ? -14.03847 -3.36688  -2.95628  1.000 48.99296  ? 521 HOH A O    1 
HETATM 9292 O O    . HOH E 3 .   ? -21.61858 -23.11989 -28.32367 1.000 52.02872  ? 522 HOH A O    1 
HETATM 9293 O O    . HOH E 3 .   ? -20.48883 -5.87320  -30.27166 1.000 47.83473  ? 523 HOH A O    1 
HETATM 9294 O O    . HOH E 3 .   ? -6.19068  2.30836   -27.89773 1.000 44.99360  ? 524 HOH A O    1 
HETATM 9295 O O    . HOH E 3 .   ? -18.63842 -6.48654  -28.60221 1.000 41.83024  ? 525 HOH A O    1 
HETATM 9296 O O    . HOH F 3 .   ? -25.64521 9.38290   -35.78706 1.000 39.41113  ? 501 HOH B O    1 
HETATM 9297 O O    . HOH F 3 .   ? -25.75425 -8.19579  -51.24374 1.000 42.49587  ? 502 HOH B O    1 
HETATM 9298 O O    . HOH F 3 .   ? -26.27679 -1.39654  -47.14817 1.000 33.69285  ? 503 HOH B O    1 
HETATM 9299 O O    . HOH F 3 .   ? -11.40179 11.18787  -41.44570 1.000 41.29848  ? 504 HOH B O    1 
HETATM 9300 O O    . HOH F 3 .   ? -13.15058 -2.28480  -35.47174 1.000 33.79644  ? 505 HOH B O    1 
HETATM 9301 O O    . HOH F 3 .   ? -21.41850 -5.57722  -39.16134 1.000 36.32784  ? 506 HOH B O    1 
HETATM 9302 O O    . HOH F 3 .   ? -44.50248 -3.21818  -51.70031 1.000 48.54004  ? 507 HOH B O    1 
HETATM 9303 O O    . HOH F 3 .   ? 3.35806   -8.57162  -45.90550 1.000 42.57910  ? 508 HOH B O    1 
HETATM 9304 O O    . HOH F 3 .   ? -30.10892 2.03589   -31.59251 1.000 42.08894  ? 509 HOH B O    1 
HETATM 9305 O O    . HOH F 3 .   ? -8.84148  10.70408  -43.51955 1.000 51.86819  ? 510 HOH B O    1 
HETATM 9306 O O    . HOH F 3 .   ? -0.974    -2.000    -43.092   1.000 37.33333  ? 511 HOH B O    1 
HETATM 9307 O O    . HOH F 3 .   ? -20.36675 8.94739   -47.65528 1.000 37.45039  ? 512 HOH B O    1 
HETATM 9308 O O    . HOH F 3 .   ? -12.98938 1.61660   -37.71775 1.000 36.61761  ? 513 HOH B O    1 
HETATM 9309 O O    . HOH F 3 .   ? -28.90548 -0.67797  -54.70547 1.000 41.30852  ? 514 HOH B O    1 
HETATM 9310 O O    . HOH F 3 .   ? -15.21078 12.96475  -31.12483 1.000 38.75362  ? 515 HOH B O    1 
HETATM 9311 O O    . HOH F 3 .   ? -33.50031 3.22968   -53.74269 1.000 40.19070  ? 516 HOH B O    1 
HETATM 9312 O O    . HOH F 3 .   ? -15.38518 6.30204   -43.02745 1.000 39.37633  ? 517 HOH B O    1 
HETATM 9313 O O    . HOH F 3 .   ? -34.61383 6.79503   -47.70451 1.000 33.41201  ? 518 HOH B O    1 
HETATM 9314 O O    . HOH F 3 .   ? -11.33029 -9.32602  -36.86471 1.000 32.24263  ? 519 HOH B O    1 
HETATM 9315 O O    . HOH F 3 .   ? -20.53766 -12.20506 -49.89541 1.000 47.15921  ? 520 HOH B O    1 
HETATM 9316 O O    . HOH F 3 .   ? -32.83946 9.99325   -56.62825 1.000 42.95662  ? 521 HOH B O    1 
HETATM 9317 O O    . HOH F 3 .   ? -9.86988  0.58030   -40.50198 1.000 36.86718  ? 522 HOH B O    1 
HETATM 9318 O O    . HOH F 3 .   ? -22.54466 -1.17960  -53.58591 1.000 39.35640  ? 523 HOH B O    1 
HETATM 9319 O O    . HOH F 3 .   ? -6.58664  -1.92816  -42.27177 1.000 37.19029  ? 524 HOH B O    1 
HETATM 9320 O O    . HOH F 3 .   ? -28.92029 3.48413   -54.28772 1.000 38.20560  ? 525 HOH B O    1 
HETATM 9321 O O    . HOH F 3 .   ? -12.50863 -1.75191  -32.57189 1.000 35.84254  ? 526 HOH B O    1 
HETATM 9322 O O    . HOH F 3 .   ? -26.15114 -10.18521 -43.68063 1.000 41.30465  ? 527 HOH B O    1 
HETATM 9323 O O    . HOH F 3 .   ? -45.87196 7.27726   -54.51734 1.000 47.34465  ? 528 HOH B O    1 
HETATM 9324 O O    . HOH F 3 .   ? -11.94061 0.97702   -41.71678 1.000 37.86204  ? 529 HOH B O    1 
HETATM 9325 O O    . HOH F 3 .   ? -9.73496  -1.14604  -32.59674 1.000 40.60959  ? 530 HOH B O    1 
HETATM 9326 O O    . HOH F 3 .   ? -31.20171 2.25714   -28.63278 1.000 52.10396  ? 531 HOH B O    1 
HETATM 9327 O O    . HOH F 3 .   ? -16.86280 -6.05074  -26.82512 1.000 43.81790  ? 532 HOH B O    1 
# 
