data_9BKV
# 
_entry.id   9BKV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BKV         pdb_00009bkv 10.2210/pdb9bkv/pdb 
WWPDB D_1000283493 ?            ?                   
EMDB  EMD-44646    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-20 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_last'               
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BKV 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-29 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'DosP R97A bent form' 
_pdbx_database_related.db_id          EMD-44646 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              daniel.kober@utsouthwestern.edu 
_pdbx_contact_author.name_first         Daniel 
_pdbx_contact_author.name_last          Kober 
_pdbx_contact_author.name_mi            L 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8657-9348 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kumar, P.'   1 0000-0002-7025-5530 
'Kober, D.L.' 2 0000-0001-8657-9348 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9653 
_citation.page_last                 9653 
_citation.title                     
'Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53942-7 
_citation.pdbx_database_id_PubMed   39511182 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wu, W.'                1 ? 
primary 'Kumar, P.'             2 ? 
primary 'Brautigam, C.A.'       3 ? 
primary 'Tso, S.C.'             4 ? 
primary 'Baniasadi, H.R.'       5 ? 
primary 'Kober, D.L.'           6 ? 
primary 'Gilles-Gonzalez, M.A.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Oxygen sensor protein DosP'      91181.156 2 3.1.4.52 R97A ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487   2 ?        ?    ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Direct oxygen-sensing phosphodiesterase,Direct oxygen sensor protein,Ec DOS,Heme-regulated cyclic di-GMP phosphodiesterase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MRQDAEVIMKLTDADSAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEY
IRHNREGGKARVEGMSAELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVL
DPERHIVQCNRAFTEMFGYCISEASGMQPDTLLNTPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVY
DVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAE
IQNAQSWSATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIAD
ELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAI
SNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPAL
SVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSL
PVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMS
SVLPLKI
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MRQDAEVIMKLTDADSAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEY
IRHNREGGKARVEGMSAELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVL
DPERHIVQCNRAFTEMFGYCISEASGMQPDTLLNTPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVY
DVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAE
IQNAQSWSATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIAD
ELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAI
SNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPAL
SVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSL
PVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMS
SVLPLKI
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'PROTOPORPHYRIN IX CONTAINING FE' 
_pdbx_entity_nonpoly.comp_id     HEM 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ARG n 
1 3   GLN n 
1 4   ASP n 
1 5   ALA n 
1 6   GLU n 
1 7   VAL n 
1 8   ILE n 
1 9   MET n 
1 10  LYS n 
1 11  LEU n 
1 12  THR n 
1 13  ASP n 
1 14  ALA n 
1 15  ASP n 
1 16  SER n 
1 17  ALA n 
1 18  ALA n 
1 19  ASP n 
1 20  GLY n 
1 21  ILE n 
1 22  PHE n 
1 23  PHE n 
1 24  PRO n 
1 25  ALA n 
1 26  LEU n 
1 27  GLU n 
1 28  GLN n 
1 29  ASN n 
1 30  MET n 
1 31  MET n 
1 32  GLY n 
1 33  ALA n 
1 34  VAL n 
1 35  LEU n 
1 36  ILE n 
1 37  ASN n 
1 38  GLU n 
1 39  ASN n 
1 40  ASP n 
1 41  GLU n 
1 42  VAL n 
1 43  MET n 
1 44  PHE n 
1 45  PHE n 
1 46  ASN n 
1 47  PRO n 
1 48  ALA n 
1 49  ALA n 
1 50  GLU n 
1 51  LYS n 
1 52  LEU n 
1 53  TRP n 
1 54  GLY n 
1 55  TYR n 
1 56  LYS n 
1 57  ARG n 
1 58  GLU n 
1 59  GLU n 
1 60  VAL n 
1 61  ILE n 
1 62  GLY n 
1 63  ASN n 
1 64  ASN n 
1 65  ILE n 
1 66  ASP n 
1 67  MET n 
1 68  LEU n 
1 69  ILE n 
1 70  PRO n 
1 71  ARG n 
1 72  ASP n 
1 73  LEU n 
1 74  ARG n 
1 75  PRO n 
1 76  ALA n 
1 77  HIS n 
1 78  PRO n 
1 79  GLU n 
1 80  TYR n 
1 81  ILE n 
1 82  ARG n 
1 83  HIS n 
1 84  ASN n 
1 85  ARG n 
1 86  GLU n 
1 87  GLY n 
1 88  GLY n 
1 89  LYS n 
1 90  ALA n 
1 91  ARG n 
1 92  VAL n 
1 93  GLU n 
1 94  GLY n 
1 95  MET n 
1 96  SER n 
1 97  ALA n 
1 98  GLU n 
1 99  LEU n 
1 100 GLN n 
1 101 LEU n 
1 102 GLU n 
1 103 LYS n 
1 104 LYS n 
1 105 ASP n 
1 106 GLY n 
1 107 SER n 
1 108 LYS n 
1 109 ILE n 
1 110 TRP n 
1 111 THR n 
1 112 ARG n 
1 113 PHE n 
1 114 ALA n 
1 115 LEU n 
1 116 SER n 
1 117 LYS n 
1 118 VAL n 
1 119 SER n 
1 120 ALA n 
1 121 GLU n 
1 122 GLY n 
1 123 LYS n 
1 124 VAL n 
1 125 TYR n 
1 126 TYR n 
1 127 LEU n 
1 128 ALA n 
1 129 LEU n 
1 130 VAL n 
1 131 ARG n 
1 132 ASP n 
1 133 ALA n 
1 134 SER n 
1 135 VAL n 
1 136 GLU n 
1 137 MET n 
1 138 ALA n 
1 139 GLN n 
1 140 LYS n 
1 141 GLU n 
1 142 GLN n 
1 143 THR n 
1 144 ARG n 
1 145 GLN n 
1 146 LEU n 
1 147 ILE n 
1 148 ILE n 
1 149 ALA n 
1 150 VAL n 
1 151 ASP n 
1 152 HIS n 
1 153 LEU n 
1 154 ASP n 
1 155 ARG n 
1 156 PRO n 
1 157 VAL n 
1 158 ILE n 
1 159 VAL n 
1 160 LEU n 
1 161 ASP n 
1 162 PRO n 
1 163 GLU n 
1 164 ARG n 
1 165 HIS n 
1 166 ILE n 
1 167 VAL n 
1 168 GLN n 
1 169 CYS n 
1 170 ASN n 
1 171 ARG n 
1 172 ALA n 
1 173 PHE n 
1 174 THR n 
1 175 GLU n 
1 176 MET n 
1 177 PHE n 
1 178 GLY n 
1 179 TYR n 
1 180 CYS n 
1 181 ILE n 
1 182 SER n 
1 183 GLU n 
1 184 ALA n 
1 185 SER n 
1 186 GLY n 
1 187 MET n 
1 188 GLN n 
1 189 PRO n 
1 190 ASP n 
1 191 THR n 
1 192 LEU n 
1 193 LEU n 
1 194 ASN n 
1 195 THR n 
1 196 PRO n 
1 197 GLU n 
1 198 PHE n 
1 199 PRO n 
1 200 ALA n 
1 201 ASP n 
1 202 ASN n 
1 203 ARG n 
1 204 ILE n 
1 205 ARG n 
1 206 LEU n 
1 207 GLN n 
1 208 GLN n 
1 209 LEU n 
1 210 LEU n 
1 211 TRP n 
1 212 LYS n 
1 213 THR n 
1 214 ALA n 
1 215 ARG n 
1 216 ASP n 
1 217 GLN n 
1 218 ASP n 
1 219 GLU n 
1 220 PHE n 
1 221 LEU n 
1 222 LEU n 
1 223 LEU n 
1 224 THR n 
1 225 ARG n 
1 226 THR n 
1 227 GLY n 
1 228 GLU n 
1 229 LYS n 
1 230 ILE n 
1 231 TRP n 
1 232 ILE n 
1 233 LYS n 
1 234 ALA n 
1 235 SER n 
1 236 ILE n 
1 237 SER n 
1 238 PRO n 
1 239 VAL n 
1 240 TYR n 
1 241 ASP n 
1 242 VAL n 
1 243 LEU n 
1 244 ALA n 
1 245 HIS n 
1 246 LEU n 
1 247 GLN n 
1 248 ASN n 
1 249 LEU n 
1 250 VAL n 
1 251 MET n 
1 252 THR n 
1 253 PHE n 
1 254 SER n 
1 255 ASP n 
1 256 ILE n 
1 257 THR n 
1 258 GLU n 
1 259 GLU n 
1 260 ARG n 
1 261 GLN n 
1 262 ILE n 
1 263 ARG n 
1 264 GLN n 
1 265 LEU n 
1 266 GLU n 
1 267 GLY n 
1 268 ASN n 
1 269 ILE n 
1 270 LEU n 
1 271 ALA n 
1 272 ALA n 
1 273 MET n 
1 274 CYS n 
1 275 SER n 
1 276 SER n 
1 277 PRO n 
1 278 PRO n 
1 279 PHE n 
1 280 HIS n 
1 281 GLU n 
1 282 MET n 
1 283 GLY n 
1 284 GLU n 
1 285 ILE n 
1 286 ILE n 
1 287 CYS n 
1 288 ARG n 
1 289 ASN n 
1 290 ILE n 
1 291 GLU n 
1 292 SER n 
1 293 VAL n 
1 294 LEU n 
1 295 ASN n 
1 296 GLU n 
1 297 SER n 
1 298 HIS n 
1 299 VAL n 
1 300 SER n 
1 301 LEU n 
1 302 PHE n 
1 303 ALA n 
1 304 LEU n 
1 305 ARG n 
1 306 ASN n 
1 307 GLY n 
1 308 MET n 
1 309 PRO n 
1 310 ILE n 
1 311 HIS n 
1 312 TRP n 
1 313 ALA n 
1 314 SER n 
1 315 SER n 
1 316 SER n 
1 317 HIS n 
1 318 GLY n 
1 319 ALA n 
1 320 GLU n 
1 321 ILE n 
1 322 GLN n 
1 323 ASN n 
1 324 ALA n 
1 325 GLN n 
1 326 SER n 
1 327 TRP n 
1 328 SER n 
1 329 ALA n 
1 330 THR n 
1 331 ILE n 
1 332 ARG n 
1 333 GLN n 
1 334 ARG n 
1 335 ASP n 
1 336 GLY n 
1 337 ALA n 
1 338 PRO n 
1 339 ALA n 
1 340 GLY n 
1 341 ILE n 
1 342 LEU n 
1 343 GLN n 
1 344 ILE n 
1 345 LYS n 
1 346 THR n 
1 347 SER n 
1 348 SER n 
1 349 GLY n 
1 350 ALA n 
1 351 GLU n 
1 352 THR n 
1 353 SER n 
1 354 ALA n 
1 355 PHE n 
1 356 ILE n 
1 357 GLU n 
1 358 ARG n 
1 359 VAL n 
1 360 ALA n 
1 361 ASP n 
1 362 ILE n 
1 363 SER n 
1 364 GLN n 
1 365 HIS n 
1 366 MET n 
1 367 ALA n 
1 368 ALA n 
1 369 LEU n 
1 370 ALA n 
1 371 LEU n 
1 372 GLU n 
1 373 GLN n 
1 374 GLU n 
1 375 LYS n 
1 376 SER n 
1 377 ARG n 
1 378 GLN n 
1 379 HIS n 
1 380 ILE n 
1 381 GLU n 
1 382 GLN n 
1 383 LEU n 
1 384 ILE n 
1 385 GLN n 
1 386 PHE n 
1 387 ASP n 
1 388 PRO n 
1 389 MET n 
1 390 THR n 
1 391 GLY n 
1 392 LEU n 
1 393 PRO n 
1 394 ASN n 
1 395 ARG n 
1 396 ASN n 
1 397 ASN n 
1 398 LEU n 
1 399 HIS n 
1 400 ASN n 
1 401 TYR n 
1 402 LEU n 
1 403 ASP n 
1 404 ASP n 
1 405 LEU n 
1 406 VAL n 
1 407 ASP n 
1 408 LYS n 
1 409 ALA n 
1 410 VAL n 
1 411 SER n 
1 412 PRO n 
1 413 VAL n 
1 414 VAL n 
1 415 TYR n 
1 416 LEU n 
1 417 ILE n 
1 418 GLY n 
1 419 VAL n 
1 420 ASP n 
1 421 HIS n 
1 422 ILE n 
1 423 GLN n 
1 424 ASP n 
1 425 VAL n 
1 426 ILE n 
1 427 ASP n 
1 428 SER n 
1 429 LEU n 
1 430 GLY n 
1 431 TYR n 
1 432 ALA n 
1 433 TRP n 
1 434 ALA n 
1 435 ASP n 
1 436 GLN n 
1 437 ALA n 
1 438 LEU n 
1 439 LEU n 
1 440 GLU n 
1 441 VAL n 
1 442 VAL n 
1 443 ASN n 
1 444 ARG n 
1 445 PHE n 
1 446 ARG n 
1 447 GLU n 
1 448 LYS n 
1 449 LEU n 
1 450 LYS n 
1 451 PRO n 
1 452 ASP n 
1 453 GLN n 
1 454 TYR n 
1 455 LEU n 
1 456 CYS n 
1 457 ARG n 
1 458 ILE n 
1 459 GLU n 
1 460 GLY n 
1 461 THR n 
1 462 GLN n 
1 463 PHE n 
1 464 VAL n 
1 465 LEU n 
1 466 VAL n 
1 467 SER n 
1 468 LEU n 
1 469 GLU n 
1 470 ASN n 
1 471 ASP n 
1 472 VAL n 
1 473 SER n 
1 474 ASN n 
1 475 ILE n 
1 476 THR n 
1 477 GLN n 
1 478 ILE n 
1 479 ALA n 
1 480 ASP n 
1 481 GLU n 
1 482 LEU n 
1 483 ARG n 
1 484 ASN n 
1 485 VAL n 
1 486 VAL n 
1 487 SER n 
1 488 LYS n 
1 489 PRO n 
1 490 ILE n 
1 491 MET n 
1 492 ILE n 
1 493 ASP n 
1 494 ASP n 
1 495 LYS n 
1 496 PRO n 
1 497 PHE n 
1 498 PRO n 
1 499 LEU n 
1 500 THR n 
1 501 LEU n 
1 502 SER n 
1 503 ILE n 
1 504 GLY n 
1 505 ILE n 
1 506 SER n 
1 507 TYR n 
1 508 ASP n 
1 509 LEU n 
1 510 GLY n 
1 511 LYS n 
1 512 ASN n 
1 513 ARG n 
1 514 ASP n 
1 515 TYR n 
1 516 LEU n 
1 517 LEU n 
1 518 SER n 
1 519 THR n 
1 520 ALA n 
1 521 HIS n 
1 522 ASN n 
1 523 ALA n 
1 524 MET n 
1 525 ASP n 
1 526 TYR n 
1 527 ILE n 
1 528 ARG n 
1 529 LYS n 
1 530 ASN n 
1 531 GLY n 
1 532 GLY n 
1 533 ASN n 
1 534 GLY n 
1 535 TRP n 
1 536 GLN n 
1 537 PHE n 
1 538 PHE n 
1 539 SER n 
1 540 PRO n 
1 541 ALA n 
1 542 MET n 
1 543 ASN n 
1 544 GLU n 
1 545 MET n 
1 546 VAL n 
1 547 LYS n 
1 548 GLU n 
1 549 ARG n 
1 550 LEU n 
1 551 VAL n 
1 552 LEU n 
1 553 GLY n 
1 554 ALA n 
1 555 ALA n 
1 556 LEU n 
1 557 LYS n 
1 558 GLU n 
1 559 ALA n 
1 560 ILE n 
1 561 SER n 
1 562 ASN n 
1 563 ASN n 
1 564 GLN n 
1 565 LEU n 
1 566 LYS n 
1 567 LEU n 
1 568 VAL n 
1 569 TYR n 
1 570 GLN n 
1 571 PRO n 
1 572 GLN n 
1 573 ILE n 
1 574 PHE n 
1 575 ALA n 
1 576 GLU n 
1 577 THR n 
1 578 GLY n 
1 579 GLU n 
1 580 LEU n 
1 581 TYR n 
1 582 GLY n 
1 583 ILE n 
1 584 GLU n 
1 585 ALA n 
1 586 LEU n 
1 587 ALA n 
1 588 ARG n 
1 589 TRP n 
1 590 HIS n 
1 591 ASP n 
1 592 PRO n 
1 593 LEU n 
1 594 HIS n 
1 595 GLY n 
1 596 HIS n 
1 597 VAL n 
1 598 PRO n 
1 599 PRO n 
1 600 SER n 
1 601 ARG n 
1 602 PHE n 
1 603 ILE n 
1 604 PRO n 
1 605 LEU n 
1 606 ALA n 
1 607 GLU n 
1 608 GLU n 
1 609 ILE n 
1 610 GLY n 
1 611 GLU n 
1 612 ILE n 
1 613 GLU n 
1 614 ASN n 
1 615 ILE n 
1 616 GLY n 
1 617 ARG n 
1 618 TRP n 
1 619 VAL n 
1 620 ILE n 
1 621 ALA n 
1 622 GLU n 
1 623 ALA n 
1 624 CYS n 
1 625 ARG n 
1 626 GLN n 
1 627 LEU n 
1 628 ALA n 
1 629 GLU n 
1 630 TRP n 
1 631 ARG n 
1 632 SER n 
1 633 GLN n 
1 634 ASN n 
1 635 ILE n 
1 636 HIS n 
1 637 ILE n 
1 638 PRO n 
1 639 ALA n 
1 640 LEU n 
1 641 SER n 
1 642 VAL n 
1 643 ASN n 
1 644 LEU n 
1 645 SER n 
1 646 ALA n 
1 647 LEU n 
1 648 HIS n 
1 649 PHE n 
1 650 ARG n 
1 651 SER n 
1 652 ASN n 
1 653 GLN n 
1 654 LEU n 
1 655 PRO n 
1 656 ASN n 
1 657 GLN n 
1 658 VAL n 
1 659 SER n 
1 660 ASP n 
1 661 ALA n 
1 662 MET n 
1 663 HIS n 
1 664 ALA n 
1 665 TRP n 
1 666 GLY n 
1 667 ILE n 
1 668 ASP n 
1 669 GLY n 
1 670 HIS n 
1 671 GLN n 
1 672 LEU n 
1 673 THR n 
1 674 VAL n 
1 675 GLU n 
1 676 ILE n 
1 677 THR n 
1 678 GLU n 
1 679 SER n 
1 680 MET n 
1 681 MET n 
1 682 MET n 
1 683 GLU n 
1 684 HIS n 
1 685 ASP n 
1 686 THR n 
1 687 GLU n 
1 688 ILE n 
1 689 PHE n 
1 690 LYS n 
1 691 ARG n 
1 692 ILE n 
1 693 GLN n 
1 694 ILE n 
1 695 LEU n 
1 696 ARG n 
1 697 ASP n 
1 698 MET n 
1 699 GLY n 
1 700 VAL n 
1 701 GLY n 
1 702 LEU n 
1 703 SER n 
1 704 VAL n 
1 705 ASP n 
1 706 ASP n 
1 707 PHE n 
1 708 GLY n 
1 709 THR n 
1 710 GLY n 
1 711 PHE n 
1 712 SER n 
1 713 GLY n 
1 714 LEU n 
1 715 SER n 
1 716 ARG n 
1 717 LEU n 
1 718 VAL n 
1 719 SER n 
1 720 LEU n 
1 721 PRO n 
1 722 VAL n 
1 723 THR n 
1 724 GLU n 
1 725 ILE n 
1 726 LYS n 
1 727 ILE n 
1 728 ASP n 
1 729 LYS n 
1 730 SER n 
1 731 PHE n 
1 732 VAL n 
1 733 ASP n 
1 734 ARG n 
1 735 CYS n 
1 736 LEU n 
1 737 THR n 
1 738 GLU n 
1 739 LYS n 
1 740 ARG n 
1 741 ILE n 
1 742 LEU n 
1 743 ALA n 
1 744 LEU n 
1 745 LEU n 
1 746 GLU n 
1 747 ALA n 
1 748 ILE n 
1 749 THR n 
1 750 SER n 
1 751 ILE n 
1 752 GLY n 
1 753 GLN n 
1 754 SER n 
1 755 LEU n 
1 756 ASN n 
1 757 LEU n 
1 758 THR n 
1 759 VAL n 
1 760 VAL n 
1 761 ALA n 
1 762 GLU n 
1 763 GLY n 
1 764 VAL n 
1 765 GLU n 
1 766 THR n 
1 767 LYS n 
1 768 GLU n 
1 769 GLN n 
1 770 PHE n 
1 771 GLU n 
1 772 MET n 
1 773 LEU n 
1 774 ARG n 
1 775 LYS n 
1 776 ILE n 
1 777 HIS n 
1 778 CYS n 
1 779 ARG n 
1 780 VAL n 
1 781 ILE n 
1 782 GLN n 
1 783 GLY n 
1 784 TYR n 
1 785 PHE n 
1 786 PHE n 
1 787 SER n 
1 788 ARG n 
1 789 PRO n 
1 790 LEU n 
1 791 PRO n 
1 792 ALA n 
1 793 GLU n 
1 794 GLU n 
1 795 ILE n 
1 796 PRO n 
1 797 GLY n 
1 798 TRP n 
1 799 MET n 
1 800 SER n 
1 801 SER n 
1 802 VAL n 
1 803 LEU n 
1 804 PRO n 
1 805 LEU n 
1 806 LYS n 
1 807 ILE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   807 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'dosP, dos, pdeO, yddU, b1489, JW1484' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     562 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ARG 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ASP 4   4   ?   ?   ?   A . n 
A 1 5   ALA 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   VAL 7   7   ?   ?   ?   A . n 
A 1 8   ILE 8   8   ?   ?   ?   A . n 
A 1 9   MET 9   9   ?   ?   ?   A . n 
A 1 10  LYS 10  10  ?   ?   ?   A . n 
A 1 11  LEU 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  ASP 13  13  ?   ?   ?   A . n 
A 1 14  ALA 14  14  ?   ?   ?   A . n 
A 1 15  ASP 15  15  ?   ?   ?   A . n 
A 1 16  SER 16  16  ?   ?   ?   A . n 
A 1 17  ALA 17  17  ?   ?   ?   A . n 
A 1 18  ALA 18  18  ?   ?   ?   A . n 
A 1 19  ASP 19  19  ?   ?   ?   A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  PHE 23  23  23  PHE PHE A . n 
A 1 24  PRO 24  24  24  PRO PRO A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  GLU 27  27  27  GLU GLU A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  ASN 29  29  29  ASN ASN A . n 
A 1 30  MET 30  30  30  MET MET A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  ASN 37  37  37  ASN ASN A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  ASP 40  40  40  ASP ASP A . n 
A 1 41  GLU 41  41  41  GLU GLU A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  MET 43  43  43  MET MET A . n 
A 1 44  PHE 44  44  44  PHE PHE A . n 
A 1 45  PHE 45  45  45  PHE PHE A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  TRP 53  53  53  TRP TRP A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  LYS 56  56  56  LYS LYS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  GLU 58  58  58  GLU GLU A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  ILE 61  61  61  ILE ILE A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  ASN 64  64  64  ASN ASN A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  MET 67  67  67  MET MET A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  PRO 70  70  70  PRO PRO A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  TYR 80  80  80  TYR TYR A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  ARG 82  82  82  ARG ARG A . n 
A 1 83  HIS 83  83  83  HIS HIS A . n 
A 1 84  ASN 84  84  84  ASN ASN A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  GLY 88  88  88  GLY GLY A . n 
A 1 89  LYS 89  89  89  LYS LYS A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ARG 91  91  91  ARG ARG A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  MET 95  95  95  MET MET A . n 
A 1 96  SER 96  96  96  SER SER A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 GLN 100 100 100 GLN GLN A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 TRP 110 110 110 TRP TRP A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 LYS 117 117 117 LYS LYS A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 SER 119 119 119 SER SER A . n 
A 1 120 ALA 120 120 120 ALA ALA A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 MET 137 137 137 MET MET A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 GLN 139 139 139 GLN GLN A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 GLN 142 142 142 GLN GLN A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 ARG 144 144 144 ARG ARG A . n 
A 1 145 GLN 145 145 145 GLN GLN A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 ASP 151 151 151 ASP ASP A . n 
A 1 152 HIS 152 152 152 HIS HIS A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ASP 154 154 154 ASP ASP A . n 
A 1 155 ARG 155 155 155 ARG ARG A . n 
A 1 156 PRO 156 156 156 PRO PRO A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 GLU 163 163 163 GLU GLU A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 GLN 168 168 168 GLN GLN A . n 
A 1 169 CYS 169 169 169 CYS CYS A . n 
A 1 170 ASN 170 170 170 ASN ASN A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 GLU 175 175 175 GLU GLU A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 PHE 177 177 177 PHE PHE A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 CYS 180 180 180 CYS CYS A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 GLU 183 183 183 GLU GLU A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 GLY 186 186 186 GLY GLY A . n 
A 1 187 MET 187 187 187 MET MET A . n 
A 1 188 GLN 188 188 188 GLN GLN A . n 
A 1 189 PRO 189 189 189 PRO PRO A . n 
A 1 190 ASP 190 190 190 ASP ASP A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 ASN 194 194 194 ASN ASN A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 PRO 196 196 196 PRO PRO A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 PRO 199 199 199 PRO PRO A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 ASP 201 201 201 ASP ASP A . n 
A 1 202 ASN 202 202 202 ASN ASN A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 ILE 204 204 204 ILE ILE A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 GLN 207 207 207 GLN GLN A . n 
A 1 208 GLN 208 208 208 GLN GLN A . n 
A 1 209 LEU 209 209 209 LEU LEU A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 LYS 212 212 212 LYS LYS A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 ARG 215 215 215 ARG ARG A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 GLU 219 219 219 GLU GLU A . n 
A 1 220 PHE 220 220 220 PHE PHE A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 LYS 229 229 229 LYS LYS A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 PRO 238 238 238 PRO PRO A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 ASP 241 241 241 ASP ASP A . n 
A 1 242 VAL 242 242 242 VAL VAL A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 GLN 247 247 247 GLN GLN A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 VAL 250 250 250 VAL VAL A . n 
A 1 251 MET 251 251 251 MET MET A . n 
A 1 252 THR 252 252 252 THR THR A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ASP 255 255 255 ASP ASP A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 GLU 259 259 259 GLU GLU A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 ILE 262 262 262 ILE ILE A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 GLN 264 264 264 GLN GLN A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 ASN 268 268 268 ASN ASN A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 ALA 271 271 271 ALA ALA A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 MET 273 273 273 MET MET A . n 
A 1 274 CYS 274 274 274 CYS CYS A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 PRO 277 277 277 PRO PRO A . n 
A 1 278 PRO 278 278 278 PRO PRO A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 HIS 280 280 280 HIS HIS A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 MET 282 282 282 MET MET A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 CYS 287 287 287 CYS CYS A . n 
A 1 288 ARG 288 288 288 ARG ARG A . n 
A 1 289 ASN 289 289 289 ASN ASN A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 SER 292 292 292 SER SER A . n 
A 1 293 VAL 293 293 293 VAL VAL A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 ASN 295 295 295 ASN ASN A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 SER 297 297 297 SER SER A . n 
A 1 298 HIS 298 298 298 HIS HIS A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 SER 300 300 300 SER SER A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LEU 304 304 304 LEU LEU A . n 
A 1 305 ARG 305 305 305 ARG ARG A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 GLY 307 307 307 GLY GLY A . n 
A 1 308 MET 308 308 308 MET MET A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 HIS 311 311 311 HIS HIS A . n 
A 1 312 TRP 312 312 312 TRP TRP A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 SER 315 315 315 SER SER A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 HIS 317 317 317 HIS HIS A . n 
A 1 318 GLY 318 318 318 GLY GLY A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 GLU 320 320 320 GLU GLU A . n 
A 1 321 ILE 321 321 321 ILE ILE A . n 
A 1 322 GLN 322 322 322 GLN GLN A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 SER 328 328 328 SER SER A . n 
A 1 329 ALA 329 329 329 ALA ALA A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 ILE 331 331 331 ILE ILE A . n 
A 1 332 ARG 332 332 332 ARG ARG A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 GLY 340 340 340 GLY GLY A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 GLN 343 343 343 GLN GLN A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 THR 346 346 346 THR THR A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 SER 348 348 348 SER SER A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 THR 352 352 352 THR THR A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 ALA 354 354 354 ALA ALA A . n 
A 1 355 PHE 355 355 355 PHE PHE A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 ARG 358 358 358 ARG ARG A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ASP 361 361 361 ASP ASP A . n 
A 1 362 ILE 362 362 362 ILE ILE A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 GLN 364 364 364 GLN GLN A . n 
A 1 365 HIS 365 365 365 HIS HIS A . n 
A 1 366 MET 366 366 366 MET MET A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 GLU 374 374 374 GLU GLU A . n 
A 1 375 LYS 375 375 375 LYS LYS A . n 
A 1 376 SER 376 376 376 SER SER A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 GLN 378 378 378 GLN GLN A . n 
A 1 379 HIS 379 379 379 HIS HIS A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 GLU 381 381 381 GLU GLU A . n 
A 1 382 GLN 382 382 382 GLN GLN A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ILE 384 384 384 ILE ILE A . n 
A 1 385 GLN 385 385 385 GLN GLN A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 ASP 387 387 387 ASP ASP A . n 
A 1 388 PRO 388 388 388 PRO PRO A . n 
A 1 389 MET 389 389 389 MET MET A . n 
A 1 390 THR 390 390 390 THR THR A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 PRO 393 393 393 PRO PRO A . n 
A 1 394 ASN 394 394 394 ASN ASN A . n 
A 1 395 ARG 395 395 395 ARG ARG A . n 
A 1 396 ASN 396 396 396 ASN ASN A . n 
A 1 397 ASN 397 397 397 ASN ASN A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 HIS 399 399 399 HIS HIS A . n 
A 1 400 ASN 400 400 400 ASN ASN A . n 
A 1 401 TYR 401 401 401 TYR TYR A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 ASP 403 403 403 ASP ASP A . n 
A 1 404 ASP 404 404 404 ASP ASP A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 VAL 406 406 406 VAL VAL A . n 
A 1 407 ASP 407 407 407 ASP ASP A . n 
A 1 408 LYS 408 408 408 LYS LYS A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 VAL 410 410 410 VAL VAL A . n 
A 1 411 SER 411 411 411 SER SER A . n 
A 1 412 PRO 412 412 412 PRO PRO A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 VAL 414 414 414 VAL VAL A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 ILE 417 417 417 ILE ILE A . n 
A 1 418 GLY 418 418 418 GLY GLY A . n 
A 1 419 VAL 419 419 419 VAL VAL A . n 
A 1 420 ASP 420 420 420 ASP ASP A . n 
A 1 421 HIS 421 421 421 HIS HIS A . n 
A 1 422 ILE 422 422 422 ILE ILE A . n 
A 1 423 GLN 423 423 423 GLN GLN A . n 
A 1 424 ASP 424 424 424 ASP ASP A . n 
A 1 425 VAL 425 425 425 VAL VAL A . n 
A 1 426 ILE 426 426 426 ILE ILE A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 SER 428 428 428 SER SER A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 GLY 430 430 430 GLY GLY A . n 
A 1 431 TYR 431 431 431 TYR TYR A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 TRP 433 433 433 TRP TRP A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 ASP 435 435 435 ASP ASP A . n 
A 1 436 GLN 436 436 436 GLN GLN A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 LEU 438 438 438 LEU LEU A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 GLU 440 440 440 GLU GLU A . n 
A 1 441 VAL 441 441 441 VAL VAL A . n 
A 1 442 VAL 442 442 442 VAL VAL A . n 
A 1 443 ASN 443 443 443 ASN ASN A . n 
A 1 444 ARG 444 444 444 ARG ARG A . n 
A 1 445 PHE 445 445 445 PHE PHE A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 GLU 447 447 447 GLU GLU A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 LYS 450 450 450 LYS LYS A . n 
A 1 451 PRO 451 451 451 PRO PRO A . n 
A 1 452 ASP 452 452 452 ASP ASP A . n 
A 1 453 GLN 453 453 453 GLN GLN A . n 
A 1 454 TYR 454 454 454 TYR TYR A . n 
A 1 455 LEU 455 455 455 LEU LEU A . n 
A 1 456 CYS 456 456 456 CYS CYS A . n 
A 1 457 ARG 457 457 457 ARG ARG A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 GLY 460 460 460 GLY GLY A . n 
A 1 461 THR 461 461 461 THR THR A . n 
A 1 462 GLN 462 462 462 GLN GLN A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 VAL 464 464 464 VAL VAL A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 SER 467 467 467 SER SER A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 GLU 469 469 469 GLU GLU A . n 
A 1 470 ASN 470 470 470 ASN ASN A . n 
A 1 471 ASP 471 471 471 ASP ASP A . n 
A 1 472 VAL 472 472 472 VAL VAL A . n 
A 1 473 SER 473 473 473 SER SER A . n 
A 1 474 ASN 474 474 474 ASN ASN A . n 
A 1 475 ILE 475 475 475 ILE ILE A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 GLN 477 477 477 GLN GLN A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ALA 479 479 479 ALA ALA A . n 
A 1 480 ASP 480 480 480 ASP ASP A . n 
A 1 481 GLU 481 481 481 GLU GLU A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 ARG 483 483 483 ARG ARG A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 VAL 485 485 485 VAL VAL A . n 
A 1 486 VAL 486 486 486 VAL VAL A . n 
A 1 487 SER 487 487 487 SER SER A . n 
A 1 488 LYS 488 488 488 LYS LYS A . n 
A 1 489 PRO 489 489 489 PRO PRO A . n 
A 1 490 ILE 490 490 490 ILE ILE A . n 
A 1 491 MET 491 491 491 MET MET A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 ASP 493 493 493 ASP ASP A . n 
A 1 494 ASP 494 494 494 ASP ASP A . n 
A 1 495 LYS 495 495 495 LYS LYS A . n 
A 1 496 PRO 496 496 496 PRO PRO A . n 
A 1 497 PHE 497 497 497 PHE PHE A . n 
A 1 498 PRO 498 498 498 PRO PRO A . n 
A 1 499 LEU 499 499 499 LEU LEU A . n 
A 1 500 THR 500 500 500 THR THR A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 SER 502 502 502 SER SER A . n 
A 1 503 ILE 503 503 503 ILE ILE A . n 
A 1 504 GLY 504 504 504 GLY GLY A . n 
A 1 505 ILE 505 505 505 ILE ILE A . n 
A 1 506 SER 506 506 506 SER SER A . n 
A 1 507 TYR 507 507 507 TYR TYR A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 LEU 509 509 509 LEU LEU A . n 
A 1 510 GLY 510 510 510 GLY GLY A . n 
A 1 511 LYS 511 511 511 LYS LYS A . n 
A 1 512 ASN 512 512 512 ASN ASN A . n 
A 1 513 ARG 513 513 513 ARG ARG A . n 
A 1 514 ASP 514 514 514 ASP ASP A . n 
A 1 515 TYR 515 515 515 TYR TYR A . n 
A 1 516 LEU 516 516 516 LEU LEU A . n 
A 1 517 LEU 517 517 517 LEU LEU A . n 
A 1 518 SER 518 518 518 SER SER A . n 
A 1 519 THR 519 519 519 THR THR A . n 
A 1 520 ALA 520 520 520 ALA ALA A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 ASN 522 522 522 ASN ASN A . n 
A 1 523 ALA 523 523 523 ALA ALA A . n 
A 1 524 MET 524 524 524 MET MET A . n 
A 1 525 ASP 525 525 525 ASP ASP A . n 
A 1 526 TYR 526 526 526 TYR TYR A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 ARG 528 528 528 ARG ARG A . n 
A 1 529 LYS 529 529 529 LYS LYS A . n 
A 1 530 ASN 530 530 530 ASN ASN A . n 
A 1 531 GLY 531 531 531 GLY GLY A . n 
A 1 532 GLY 532 532 532 GLY GLY A . n 
A 1 533 ASN 533 533 533 ASN ASN A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 TRP 535 535 535 TRP TRP A . n 
A 1 536 GLN 536 536 536 GLN GLN A . n 
A 1 537 PHE 537 537 537 PHE PHE A . n 
A 1 538 PHE 538 538 538 PHE PHE A . n 
A 1 539 SER 539 539 539 SER SER A . n 
A 1 540 PRO 540 540 540 PRO PRO A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 MET 542 542 542 MET MET A . n 
A 1 543 ASN 543 543 543 ASN ASN A . n 
A 1 544 GLU 544 544 544 GLU GLU A . n 
A 1 545 MET 545 545 545 MET MET A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 LYS 547 547 547 LYS LYS A . n 
A 1 548 GLU 548 548 548 GLU GLU A . n 
A 1 549 ARG 549 549 549 ARG ARG A . n 
A 1 550 LEU 550 550 550 LEU LEU A . n 
A 1 551 VAL 551 551 551 VAL VAL A . n 
A 1 552 LEU 552 552 552 LEU LEU A . n 
A 1 553 GLY 553 553 553 GLY GLY A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 ALA 555 555 555 ALA ALA A . n 
A 1 556 LEU 556 556 556 LEU LEU A . n 
A 1 557 LYS 557 557 557 LYS LYS A . n 
A 1 558 GLU 558 558 558 GLU GLU A . n 
A 1 559 ALA 559 559 559 ALA ALA A . n 
A 1 560 ILE 560 560 560 ILE ILE A . n 
A 1 561 SER 561 561 561 SER SER A . n 
A 1 562 ASN 562 562 562 ASN ASN A . n 
A 1 563 ASN 563 563 563 ASN ASN A . n 
A 1 564 GLN 564 564 564 GLN GLN A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 LYS 566 566 566 LYS LYS A . n 
A 1 567 LEU 567 567 567 LEU LEU A . n 
A 1 568 VAL 568 568 568 VAL VAL A . n 
A 1 569 TYR 569 569 569 TYR TYR A . n 
A 1 570 GLN 570 570 570 GLN GLN A . n 
A 1 571 PRO 571 571 571 PRO PRO A . n 
A 1 572 GLN 572 572 572 GLN GLN A . n 
A 1 573 ILE 573 573 573 ILE ILE A . n 
A 1 574 PHE 574 574 574 PHE PHE A . n 
A 1 575 ALA 575 575 575 ALA ALA A . n 
A 1 576 GLU 576 576 576 GLU GLU A . n 
A 1 577 THR 577 577 577 THR THR A . n 
A 1 578 GLY 578 578 578 GLY GLY A . n 
A 1 579 GLU 579 579 579 GLU GLU A . n 
A 1 580 LEU 580 580 580 LEU LEU A . n 
A 1 581 TYR 581 581 581 TYR TYR A . n 
A 1 582 GLY 582 582 582 GLY GLY A . n 
A 1 583 ILE 583 583 583 ILE ILE A . n 
A 1 584 GLU 584 584 584 GLU GLU A . n 
A 1 585 ALA 585 585 585 ALA ALA A . n 
A 1 586 LEU 586 586 586 LEU LEU A . n 
A 1 587 ALA 587 587 587 ALA ALA A . n 
A 1 588 ARG 588 588 588 ARG ARG A . n 
A 1 589 TRP 589 589 589 TRP TRP A . n 
A 1 590 HIS 590 590 590 HIS HIS A . n 
A 1 591 ASP 591 591 591 ASP ASP A . n 
A 1 592 PRO 592 592 592 PRO PRO A . n 
A 1 593 LEU 593 593 593 LEU LEU A . n 
A 1 594 HIS 594 594 594 HIS HIS A . n 
A 1 595 GLY 595 595 595 GLY GLY A . n 
A 1 596 HIS 596 596 596 HIS HIS A . n 
A 1 597 VAL 597 597 597 VAL VAL A . n 
A 1 598 PRO 598 598 598 PRO PRO A . n 
A 1 599 PRO 599 599 599 PRO PRO A . n 
A 1 600 SER 600 600 600 SER SER A . n 
A 1 601 ARG 601 601 601 ARG ARG A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 ILE 603 603 603 ILE ILE A . n 
A 1 604 PRO 604 604 604 PRO PRO A . n 
A 1 605 LEU 605 605 605 LEU LEU A . n 
A 1 606 ALA 606 606 606 ALA ALA A . n 
A 1 607 GLU 607 607 607 GLU GLU A . n 
A 1 608 GLU 608 608 608 GLU GLU A . n 
A 1 609 ILE 609 609 609 ILE ILE A . n 
A 1 610 GLY 610 610 610 GLY GLY A . n 
A 1 611 GLU 611 611 611 GLU GLU A . n 
A 1 612 ILE 612 612 612 ILE ILE A . n 
A 1 613 GLU 613 613 613 GLU GLU A . n 
A 1 614 ASN 614 614 614 ASN ASN A . n 
A 1 615 ILE 615 615 615 ILE ILE A . n 
A 1 616 GLY 616 616 616 GLY GLY A . n 
A 1 617 ARG 617 617 617 ARG ARG A . n 
A 1 618 TRP 618 618 618 TRP TRP A . n 
A 1 619 VAL 619 619 619 VAL VAL A . n 
A 1 620 ILE 620 620 620 ILE ILE A . n 
A 1 621 ALA 621 621 621 ALA ALA A . n 
A 1 622 GLU 622 622 622 GLU GLU A . n 
A 1 623 ALA 623 623 623 ALA ALA A . n 
A 1 624 CYS 624 624 624 CYS CYS A . n 
A 1 625 ARG 625 625 625 ARG ARG A . n 
A 1 626 GLN 626 626 626 GLN GLN A . n 
A 1 627 LEU 627 627 627 LEU LEU A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 GLU 629 629 629 GLU GLU A . n 
A 1 630 TRP 630 630 630 TRP TRP A . n 
A 1 631 ARG 631 631 631 ARG ARG A . n 
A 1 632 SER 632 632 632 SER SER A . n 
A 1 633 GLN 633 633 633 GLN GLN A . n 
A 1 634 ASN 634 634 634 ASN ASN A . n 
A 1 635 ILE 635 635 635 ILE ILE A . n 
A 1 636 HIS 636 636 636 HIS HIS A . n 
A 1 637 ILE 637 637 637 ILE ILE A . n 
A 1 638 PRO 638 638 638 PRO PRO A . n 
A 1 639 ALA 639 639 639 ALA ALA A . n 
A 1 640 LEU 640 640 640 LEU LEU A . n 
A 1 641 SER 641 641 641 SER SER A . n 
A 1 642 VAL 642 642 642 VAL VAL A . n 
A 1 643 ASN 643 643 643 ASN ASN A . n 
A 1 644 LEU 644 644 644 LEU LEU A . n 
A 1 645 SER 645 645 645 SER SER A . n 
A 1 646 ALA 646 646 646 ALA ALA A . n 
A 1 647 LEU 647 647 647 LEU LEU A . n 
A 1 648 HIS 648 648 648 HIS HIS A . n 
A 1 649 PHE 649 649 649 PHE PHE A . n 
A 1 650 ARG 650 650 650 ARG ARG A . n 
A 1 651 SER 651 651 651 SER SER A . n 
A 1 652 ASN 652 652 652 ASN ASN A . n 
A 1 653 GLN 653 653 653 GLN GLN A . n 
A 1 654 LEU 654 654 654 LEU LEU A . n 
A 1 655 PRO 655 655 655 PRO PRO A . n 
A 1 656 ASN 656 656 656 ASN ASN A . n 
A 1 657 GLN 657 657 657 GLN GLN A . n 
A 1 658 VAL 658 658 658 VAL VAL A . n 
A 1 659 SER 659 659 659 SER SER A . n 
A 1 660 ASP 660 660 660 ASP ASP A . n 
A 1 661 ALA 661 661 661 ALA ALA A . n 
A 1 662 MET 662 662 662 MET MET A . n 
A 1 663 HIS 663 663 663 HIS HIS A . n 
A 1 664 ALA 664 664 664 ALA ALA A . n 
A 1 665 TRP 665 665 665 TRP TRP A . n 
A 1 666 GLY 666 666 666 GLY GLY A . n 
A 1 667 ILE 667 667 667 ILE ILE A . n 
A 1 668 ASP 668 668 668 ASP ASP A . n 
A 1 669 GLY 669 669 669 GLY GLY A . n 
A 1 670 HIS 670 670 670 HIS HIS A . n 
A 1 671 GLN 671 671 671 GLN GLN A . n 
A 1 672 LEU 672 672 672 LEU LEU A . n 
A 1 673 THR 673 673 673 THR THR A . n 
A 1 674 VAL 674 674 674 VAL VAL A . n 
A 1 675 GLU 675 675 675 GLU GLU A . n 
A 1 676 ILE 676 676 676 ILE ILE A . n 
A 1 677 THR 677 677 677 THR THR A . n 
A 1 678 GLU 678 678 678 GLU GLU A . n 
A 1 679 SER 679 679 679 SER SER A . n 
A 1 680 MET 680 680 680 MET MET A . n 
A 1 681 MET 681 681 681 MET MET A . n 
A 1 682 MET 682 682 682 MET MET A . n 
A 1 683 GLU 683 683 683 GLU GLU A . n 
A 1 684 HIS 684 684 684 HIS HIS A . n 
A 1 685 ASP 685 685 685 ASP ASP A . n 
A 1 686 THR 686 686 686 THR THR A . n 
A 1 687 GLU 687 687 687 GLU GLU A . n 
A 1 688 ILE 688 688 688 ILE ILE A . n 
A 1 689 PHE 689 689 689 PHE PHE A . n 
A 1 690 LYS 690 690 690 LYS LYS A . n 
A 1 691 ARG 691 691 691 ARG ARG A . n 
A 1 692 ILE 692 692 692 ILE ILE A . n 
A 1 693 GLN 693 693 693 GLN GLN A . n 
A 1 694 ILE 694 694 694 ILE ILE A . n 
A 1 695 LEU 695 695 695 LEU LEU A . n 
A 1 696 ARG 696 696 696 ARG ARG A . n 
A 1 697 ASP 697 697 697 ASP ASP A . n 
A 1 698 MET 698 698 698 MET MET A . n 
A 1 699 GLY 699 699 699 GLY GLY A . n 
A 1 700 VAL 700 700 700 VAL VAL A . n 
A 1 701 GLY 701 701 701 GLY GLY A . n 
A 1 702 LEU 702 702 702 LEU LEU A . n 
A 1 703 SER 703 703 703 SER SER A . n 
A 1 704 VAL 704 704 704 VAL VAL A . n 
A 1 705 ASP 705 705 705 ASP ASP A . n 
A 1 706 ASP 706 706 706 ASP ASP A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 GLY 708 708 708 GLY GLY A . n 
A 1 709 THR 709 709 709 THR THR A . n 
A 1 710 GLY 710 710 710 GLY GLY A . n 
A 1 711 PHE 711 711 711 PHE PHE A . n 
A 1 712 SER 712 712 712 SER SER A . n 
A 1 713 GLY 713 713 713 GLY GLY A . n 
A 1 714 LEU 714 714 714 LEU LEU A . n 
A 1 715 SER 715 715 715 SER SER A . n 
A 1 716 ARG 716 716 716 ARG ARG A . n 
A 1 717 LEU 717 717 717 LEU LEU A . n 
A 1 718 VAL 718 718 718 VAL VAL A . n 
A 1 719 SER 719 719 719 SER SER A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 PRO 721 721 721 PRO PRO A . n 
A 1 722 VAL 722 722 722 VAL VAL A . n 
A 1 723 THR 723 723 723 THR THR A . n 
A 1 724 GLU 724 724 724 GLU GLU A . n 
A 1 725 ILE 725 725 725 ILE ILE A . n 
A 1 726 LYS 726 726 726 LYS LYS A . n 
A 1 727 ILE 727 727 727 ILE ILE A . n 
A 1 728 ASP 728 728 728 ASP ASP A . n 
A 1 729 LYS 729 729 729 LYS LYS A . n 
A 1 730 SER 730 730 730 SER SER A . n 
A 1 731 PHE 731 731 731 PHE PHE A . n 
A 1 732 VAL 732 732 732 VAL VAL A . n 
A 1 733 ASP 733 733 733 ASP ASP A . n 
A 1 734 ARG 734 734 734 ARG ARG A . n 
A 1 735 CYS 735 735 735 CYS CYS A . n 
A 1 736 LEU 736 736 736 LEU LEU A . n 
A 1 737 THR 737 737 737 THR THR A . n 
A 1 738 GLU 738 738 738 GLU GLU A . n 
A 1 739 LYS 739 739 739 LYS LYS A . n 
A 1 740 ARG 740 740 740 ARG ARG A . n 
A 1 741 ILE 741 741 741 ILE ILE A . n 
A 1 742 LEU 742 742 742 LEU LEU A . n 
A 1 743 ALA 743 743 743 ALA ALA A . n 
A 1 744 LEU 744 744 744 LEU LEU A . n 
A 1 745 LEU 745 745 745 LEU LEU A . n 
A 1 746 GLU 746 746 746 GLU GLU A . n 
A 1 747 ALA 747 747 747 ALA ALA A . n 
A 1 748 ILE 748 748 748 ILE ILE A . n 
A 1 749 THR 749 749 749 THR THR A . n 
A 1 750 SER 750 750 750 SER SER A . n 
A 1 751 ILE 751 751 751 ILE ILE A . n 
A 1 752 GLY 752 752 752 GLY GLY A . n 
A 1 753 GLN 753 753 753 GLN GLN A . n 
A 1 754 SER 754 754 754 SER SER A . n 
A 1 755 LEU 755 755 755 LEU LEU A . n 
A 1 756 ASN 756 756 756 ASN ASN A . n 
A 1 757 LEU 757 757 757 LEU LEU A . n 
A 1 758 THR 758 758 758 THR THR A . n 
A 1 759 VAL 759 759 759 VAL VAL A . n 
A 1 760 VAL 760 760 760 VAL VAL A . n 
A 1 761 ALA 761 761 761 ALA ALA A . n 
A 1 762 GLU 762 762 762 GLU GLU A . n 
A 1 763 GLY 763 763 763 GLY GLY A . n 
A 1 764 VAL 764 764 764 VAL VAL A . n 
A 1 765 GLU 765 765 765 GLU GLU A . n 
A 1 766 THR 766 766 766 THR THR A . n 
A 1 767 LYS 767 767 767 LYS LYS A . n 
A 1 768 GLU 768 768 768 GLU GLU A . n 
A 1 769 GLN 769 769 769 GLN GLN A . n 
A 1 770 PHE 770 770 770 PHE PHE A . n 
A 1 771 GLU 771 771 771 GLU GLU A . n 
A 1 772 MET 772 772 772 MET MET A . n 
A 1 773 LEU 773 773 773 LEU LEU A . n 
A 1 774 ARG 774 774 774 ARG ARG A . n 
A 1 775 LYS 775 775 775 LYS LYS A . n 
A 1 776 ILE 776 776 776 ILE ILE A . n 
A 1 777 HIS 777 777 777 HIS HIS A . n 
A 1 778 CYS 778 778 778 CYS CYS A . n 
A 1 779 ARG 779 779 779 ARG ARG A . n 
A 1 780 VAL 780 780 780 VAL VAL A . n 
A 1 781 ILE 781 781 781 ILE ILE A . n 
A 1 782 GLN 782 782 782 GLN GLN A . n 
A 1 783 GLY 783 783 783 GLY GLY A . n 
A 1 784 TYR 784 784 784 TYR TYR A . n 
A 1 785 PHE 785 785 785 PHE PHE A . n 
A 1 786 PHE 786 786 786 PHE PHE A . n 
A 1 787 SER 787 787 787 SER SER A . n 
A 1 788 ARG 788 788 788 ARG ARG A . n 
A 1 789 PRO 789 789 789 PRO PRO A . n 
A 1 790 LEU 790 790 790 LEU LEU A . n 
A 1 791 PRO 791 791 791 PRO PRO A . n 
A 1 792 ALA 792 792 792 ALA ALA A . n 
A 1 793 GLU 793 793 793 GLU GLU A . n 
A 1 794 GLU 794 794 794 GLU GLU A . n 
A 1 795 ILE 795 795 795 ILE ILE A . n 
A 1 796 PRO 796 796 796 PRO PRO A . n 
A 1 797 GLY 797 797 797 GLY GLY A . n 
A 1 798 TRP 798 798 798 TRP TRP A . n 
A 1 799 MET 799 799 799 MET MET A . n 
A 1 800 SER 800 800 800 SER SER A . n 
A 1 801 SER 801 801 801 SER SER A . n 
A 1 802 VAL 802 802 802 VAL VAL A . n 
A 1 803 LEU 803 803 803 LEU LEU A . n 
A 1 804 PRO 804 804 804 PRO PRO A . n 
A 1 805 LEU 805 805 805 LEU LEU A . n 
A 1 806 LYS 806 806 806 LYS LYS A . n 
A 1 807 ILE 807 807 807 ILE ILE A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ARG 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ASP 4   4   ?   ?   ?   B . n 
B 1 5   ALA 5   5   ?   ?   ?   B . n 
B 1 6   GLU 6   6   ?   ?   ?   B . n 
B 1 7   VAL 7   7   ?   ?   ?   B . n 
B 1 8   ILE 8   8   ?   ?   ?   B . n 
B 1 9   MET 9   9   ?   ?   ?   B . n 
B 1 10  LYS 10  10  ?   ?   ?   B . n 
B 1 11  LEU 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  ASP 13  13  ?   ?   ?   B . n 
B 1 14  ALA 14  14  ?   ?   ?   B . n 
B 1 15  ASP 15  15  ?   ?   ?   B . n 
B 1 16  SER 16  16  ?   ?   ?   B . n 
B 1 17  ALA 17  17  ?   ?   ?   B . n 
B 1 18  ALA 18  18  ?   ?   ?   B . n 
B 1 19  ASP 19  19  ?   ?   ?   B . n 
B 1 20  GLY 20  20  20  GLY GLY B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  PHE 22  22  22  PHE PHE B . n 
B 1 23  PHE 23  23  23  PHE PHE B . n 
B 1 24  PRO 24  24  24  PRO PRO B . n 
B 1 25  ALA 25  25  25  ALA ALA B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  GLU 27  27  27  GLU GLU B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  ASN 29  29  29  ASN ASN B . n 
B 1 30  MET 30  30  30  MET MET B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  ASN 37  37  37  ASN ASN B . n 
B 1 38  GLU 38  38  38  GLU GLU B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  ASP 40  40  40  ASP ASP B . n 
B 1 41  GLU 41  41  41  GLU GLU B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  MET 43  43  43  MET MET B . n 
B 1 44  PHE 44  44  44  PHE PHE B . n 
B 1 45  PHE 45  45  45  PHE PHE B . n 
B 1 46  ASN 46  46  46  ASN ASN B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  ALA 48  48  48  ALA ALA B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  GLU 50  50  50  GLU GLU B . n 
B 1 51  LYS 51  51  51  LYS LYS B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  TRP 53  53  53  TRP TRP B . n 
B 1 54  GLY 54  54  54  GLY GLY B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  LYS 56  56  56  LYS LYS B . n 
B 1 57  ARG 57  57  57  ARG ARG B . n 
B 1 58  GLU 58  58  58  GLU GLU B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  ILE 61  61  61  ILE ILE B . n 
B 1 62  GLY 62  62  62  GLY GLY B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  ASN 64  64  64  ASN ASN B . n 
B 1 65  ILE 65  65  65  ILE ILE B . n 
B 1 66  ASP 66  66  66  ASP ASP B . n 
B 1 67  MET 67  67  67  MET MET B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  PRO 70  70  70  PRO PRO B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ARG 74  74  74  ARG ARG B . n 
B 1 75  PRO 75  75  75  PRO PRO B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  HIS 77  77  77  HIS HIS B . n 
B 1 78  PRO 78  78  78  PRO PRO B . n 
B 1 79  GLU 79  79  79  GLU GLU B . n 
B 1 80  TYR 80  80  80  TYR TYR B . n 
B 1 81  ILE 81  81  81  ILE ILE B . n 
B 1 82  ARG 82  82  82  ARG ARG B . n 
B 1 83  HIS 83  83  83  HIS HIS B . n 
B 1 84  ASN 84  84  84  ASN ASN B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  GLY 87  87  87  GLY GLY B . n 
B 1 88  GLY 88  88  88  GLY GLY B . n 
B 1 89  LYS 89  89  89  LYS LYS B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  ARG 91  91  91  ARG ARG B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  GLU 93  93  93  GLU GLU B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  MET 95  95  95  MET MET B . n 
B 1 96  SER 96  96  96  SER SER B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  GLU 98  98  98  GLU GLU B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 GLN 100 100 100 GLN GLN B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 GLU 102 102 102 GLU GLU B . n 
B 1 103 LYS 103 103 103 LYS LYS B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 SER 107 107 107 SER SER B . n 
B 1 108 LYS 108 108 108 LYS LYS B . n 
B 1 109 ILE 109 109 109 ILE ILE B . n 
B 1 110 TRP 110 110 110 TRP TRP B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 PHE 113 113 113 PHE PHE B . n 
B 1 114 ALA 114 114 114 ALA ALA B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 LYS 117 117 117 LYS LYS B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 SER 119 119 119 SER SER B . n 
B 1 120 ALA 120 120 120 ALA ALA B . n 
B 1 121 GLU 121 121 121 GLU GLU B . n 
B 1 122 GLY 122 122 122 GLY GLY B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 TYR 125 125 125 TYR TYR B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 ALA 128 128 128 ALA ALA B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 ASP 132 132 132 ASP ASP B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 VAL 135 135 135 VAL VAL B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 MET 137 137 137 MET MET B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 GLN 139 139 139 GLN GLN B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 GLN 142 142 142 GLN GLN B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 ARG 144 144 144 ARG ARG B . n 
B 1 145 GLN 145 145 145 GLN GLN B . n 
B 1 146 LEU 146 146 146 LEU LEU B . n 
B 1 147 ILE 147 147 147 ILE ILE B . n 
B 1 148 ILE 148 148 148 ILE ILE B . n 
B 1 149 ALA 149 149 149 ALA ALA B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 ASP 151 151 151 ASP ASP B . n 
B 1 152 HIS 152 152 152 HIS HIS B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 ASP 154 154 154 ASP ASP B . n 
B 1 155 ARG 155 155 155 ARG ARG B . n 
B 1 156 PRO 156 156 156 PRO PRO B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 ILE 158 158 158 ILE ILE B . n 
B 1 159 VAL 159 159 159 VAL VAL B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 ASP 161 161 161 ASP ASP B . n 
B 1 162 PRO 162 162 162 PRO PRO B . n 
B 1 163 GLU 163 163 163 GLU GLU B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 HIS 165 165 165 HIS HIS B . n 
B 1 166 ILE 166 166 166 ILE ILE B . n 
B 1 167 VAL 167 167 167 VAL VAL B . n 
B 1 168 GLN 168 168 168 GLN GLN B . n 
B 1 169 CYS 169 169 169 CYS CYS B . n 
B 1 170 ASN 170 170 170 ASN ASN B . n 
B 1 171 ARG 171 171 171 ARG ARG B . n 
B 1 172 ALA 172 172 172 ALA ALA B . n 
B 1 173 PHE 173 173 173 PHE PHE B . n 
B 1 174 THR 174 174 174 THR THR B . n 
B 1 175 GLU 175 175 175 GLU GLU B . n 
B 1 176 MET 176 176 176 MET MET B . n 
B 1 177 PHE 177 177 177 PHE PHE B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 TYR 179 179 179 TYR TYR B . n 
B 1 180 CYS 180 180 180 CYS CYS B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 SER 182 182 182 SER SER B . n 
B 1 183 GLU 183 183 183 GLU GLU B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 GLY 186 186 186 GLY GLY B . n 
B 1 187 MET 187 187 187 MET MET B . n 
B 1 188 GLN 188 188 188 GLN GLN B . n 
B 1 189 PRO 189 189 189 PRO PRO B . n 
B 1 190 ASP 190 190 190 ASP ASP B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 ASN 194 194 194 ASN ASN B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 PRO 196 196 196 PRO PRO B . n 
B 1 197 GLU 197 197 197 GLU GLU B . n 
B 1 198 PHE 198 198 198 PHE PHE B . n 
B 1 199 PRO 199 199 199 PRO PRO B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 ASP 201 201 201 ASP ASP B . n 
B 1 202 ASN 202 202 202 ASN ASN B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 ILE 204 204 204 ILE ILE B . n 
B 1 205 ARG 205 205 205 ARG ARG B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 GLN 207 207 207 GLN GLN B . n 
B 1 208 GLN 208 208 208 GLN GLN B . n 
B 1 209 LEU 209 209 209 LEU LEU B . n 
B 1 210 LEU 210 210 210 LEU LEU B . n 
B 1 211 TRP 211 211 211 TRP TRP B . n 
B 1 212 LYS 212 212 212 LYS LYS B . n 
B 1 213 THR 213 213 213 THR THR B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 ARG 215 215 215 ARG ARG B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 GLU 219 219 219 GLU GLU B . n 
B 1 220 PHE 220 220 220 PHE PHE B . n 
B 1 221 LEU 221 221 221 LEU LEU B . n 
B 1 222 LEU 222 222 222 LEU LEU B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 ARG 225 225 225 ARG ARG B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLU 228 228 228 GLU GLU B . n 
B 1 229 LYS 229 229 229 LYS LYS B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 TRP 231 231 231 TRP TRP B . n 
B 1 232 ILE 232 232 232 ILE ILE B . n 
B 1 233 LYS 233 233 233 LYS LYS B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 SER 235 235 235 SER SER B . n 
B 1 236 ILE 236 236 236 ILE ILE B . n 
B 1 237 SER 237 237 237 SER SER B . n 
B 1 238 PRO 238 238 238 PRO PRO B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 TYR 240 240 240 TYR TYR B . n 
B 1 241 ASP 241 241 241 ASP ASP B . n 
B 1 242 VAL 242 242 242 VAL VAL B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 ALA 244 244 244 ALA ALA B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 GLN 247 247 247 GLN GLN B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 VAL 250 250 250 VAL VAL B . n 
B 1 251 MET 251 251 251 MET MET B . n 
B 1 252 THR 252 252 252 THR THR B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 ASP 255 255 255 ASP ASP B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 GLU 259 259 259 GLU GLU B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 GLN 261 261 261 GLN GLN B . n 
B 1 262 ILE 262 262 262 ILE ILE B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 GLN 264 264 264 GLN GLN B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 GLU 266 266 266 GLU GLU B . n 
B 1 267 GLY 267 267 267 GLY GLY B . n 
B 1 268 ASN 268 268 268 ASN ASN B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 ALA 271 271 271 ALA ALA B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 MET 273 273 273 MET MET B . n 
B 1 274 CYS 274 274 274 CYS CYS B . n 
B 1 275 SER 275 275 275 SER SER B . n 
B 1 276 SER 276 276 276 SER SER B . n 
B 1 277 PRO 277 277 277 PRO PRO B . n 
B 1 278 PRO 278 278 278 PRO PRO B . n 
B 1 279 PHE 279 279 279 PHE PHE B . n 
B 1 280 HIS 280 280 280 HIS HIS B . n 
B 1 281 GLU 281 281 281 GLU GLU B . n 
B 1 282 MET 282 282 282 MET MET B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 GLU 284 284 284 GLU GLU B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 ILE 286 286 286 ILE ILE B . n 
B 1 287 CYS 287 287 287 CYS CYS B . n 
B 1 288 ARG 288 288 288 ARG ARG B . n 
B 1 289 ASN 289 289 289 ASN ASN B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 SER 292 292 292 SER SER B . n 
B 1 293 VAL 293 293 293 VAL VAL B . n 
B 1 294 LEU 294 294 294 LEU LEU B . n 
B 1 295 ASN 295 295 295 ASN ASN B . n 
B 1 296 GLU 296 296 296 GLU GLU B . n 
B 1 297 SER 297 297 297 SER SER B . n 
B 1 298 HIS 298 298 298 HIS HIS B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 SER 300 300 300 SER SER B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LEU 304 304 304 LEU LEU B . n 
B 1 305 ARG 305 305 305 ARG ARG B . n 
B 1 306 ASN 306 306 306 ASN ASN B . n 
B 1 307 GLY 307 307 307 GLY GLY B . n 
B 1 308 MET 308 308 308 MET MET B . n 
B 1 309 PRO 309 309 309 PRO PRO B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 HIS 311 311 311 HIS HIS B . n 
B 1 312 TRP 312 312 312 TRP TRP B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 SER 314 314 314 SER SER B . n 
B 1 315 SER 315 315 315 SER SER B . n 
B 1 316 SER 316 316 316 SER SER B . n 
B 1 317 HIS 317 317 317 HIS HIS B . n 
B 1 318 GLY 318 318 318 GLY GLY B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 GLU 320 320 320 GLU GLU B . n 
B 1 321 ILE 321 321 321 ILE ILE B . n 
B 1 322 GLN 322 322 322 GLN GLN B . n 
B 1 323 ASN 323 323 323 ASN ASN B . n 
B 1 324 ALA 324 324 324 ALA ALA B . n 
B 1 325 GLN 325 325 325 GLN GLN B . n 
B 1 326 SER 326 326 326 SER SER B . n 
B 1 327 TRP 327 327 327 TRP TRP B . n 
B 1 328 SER 328 328 328 SER SER B . n 
B 1 329 ALA 329 329 329 ALA ALA B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 ILE 331 331 331 ILE ILE B . n 
B 1 332 ARG 332 332 332 ARG ARG B . n 
B 1 333 GLN 333 333 333 GLN GLN B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 ASP 335 335 335 ASP ASP B . n 
B 1 336 GLY 336 336 336 GLY GLY B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 PRO 338 338 338 PRO PRO B . n 
B 1 339 ALA 339 339 339 ALA ALA B . n 
B 1 340 GLY 340 340 340 GLY GLY B . n 
B 1 341 ILE 341 341 341 ILE ILE B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 GLN 343 343 343 GLN GLN B . n 
B 1 344 ILE 344 344 344 ILE ILE B . n 
B 1 345 LYS 345 345 345 LYS LYS B . n 
B 1 346 THR 346 346 346 THR THR B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 SER 348 348 348 SER SER B . n 
B 1 349 GLY 349 349 349 GLY GLY B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 THR 352 352 352 THR THR B . n 
B 1 353 SER 353 353 353 SER SER B . n 
B 1 354 ALA 354 354 354 ALA ALA B . n 
B 1 355 PHE 355 355 355 PHE PHE B . n 
B 1 356 ILE 356 356 356 ILE ILE B . n 
B 1 357 GLU 357 357 357 GLU GLU B . n 
B 1 358 ARG 358 358 358 ARG ARG B . n 
B 1 359 VAL 359 359 359 VAL VAL B . n 
B 1 360 ALA 360 360 360 ALA ALA B . n 
B 1 361 ASP 361 361 361 ASP ASP B . n 
B 1 362 ILE 362 362 362 ILE ILE B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 GLN 364 364 364 GLN GLN B . n 
B 1 365 HIS 365 365 365 HIS HIS B . n 
B 1 366 MET 366 366 366 MET MET B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 ALA 370 370 370 ALA ALA B . n 
B 1 371 LEU 371 371 371 LEU LEU B . n 
B 1 372 GLU 372 372 372 GLU GLU B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 GLU 374 374 374 GLU GLU B . n 
B 1 375 LYS 375 375 375 LYS LYS B . n 
B 1 376 SER 376 376 376 SER SER B . n 
B 1 377 ARG 377 377 377 ARG ARG B . n 
B 1 378 GLN 378 378 378 GLN GLN B . n 
B 1 379 HIS 379 379 ?   ?   ?   B . n 
B 1 380 ILE 380 380 ?   ?   ?   B . n 
B 1 381 GLU 381 381 ?   ?   ?   B . n 
B 1 382 GLN 382 382 ?   ?   ?   B . n 
B 1 383 LEU 383 383 ?   ?   ?   B . n 
B 1 384 ILE 384 384 384 ILE ILE B . n 
B 1 385 GLN 385 385 385 GLN GLN B . n 
B 1 386 PHE 386 386 386 PHE PHE B . n 
B 1 387 ASP 387 387 387 ASP ASP B . n 
B 1 388 PRO 388 388 388 PRO PRO B . n 
B 1 389 MET 389 389 389 MET MET B . n 
B 1 390 THR 390 390 390 THR THR B . n 
B 1 391 GLY 391 391 391 GLY GLY B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 PRO 393 393 393 PRO PRO B . n 
B 1 394 ASN 394 394 394 ASN ASN B . n 
B 1 395 ARG 395 395 395 ARG ARG B . n 
B 1 396 ASN 396 396 396 ASN ASN B . n 
B 1 397 ASN 397 397 397 ASN ASN B . n 
B 1 398 LEU 398 398 398 LEU LEU B . n 
B 1 399 HIS 399 399 399 HIS HIS B . n 
B 1 400 ASN 400 400 400 ASN ASN B . n 
B 1 401 TYR 401 401 401 TYR TYR B . n 
B 1 402 LEU 402 402 402 LEU LEU B . n 
B 1 403 ASP 403 403 403 ASP ASP B . n 
B 1 404 ASP 404 404 404 ASP ASP B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 VAL 406 406 406 VAL VAL B . n 
B 1 407 ASP 407 407 407 ASP ASP B . n 
B 1 408 LYS 408 408 408 LYS LYS B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 VAL 410 410 410 VAL VAL B . n 
B 1 411 SER 411 411 411 SER SER B . n 
B 1 412 PRO 412 412 412 PRO PRO B . n 
B 1 413 VAL 413 413 413 VAL VAL B . n 
B 1 414 VAL 414 414 414 VAL VAL B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 LEU 416 416 416 LEU LEU B . n 
B 1 417 ILE 417 417 417 ILE ILE B . n 
B 1 418 GLY 418 418 418 GLY GLY B . n 
B 1 419 VAL 419 419 419 VAL VAL B . n 
B 1 420 ASP 420 420 420 ASP ASP B . n 
B 1 421 HIS 421 421 421 HIS HIS B . n 
B 1 422 ILE 422 422 422 ILE ILE B . n 
B 1 423 GLN 423 423 423 GLN GLN B . n 
B 1 424 ASP 424 424 424 ASP ASP B . n 
B 1 425 VAL 425 425 425 VAL VAL B . n 
B 1 426 ILE 426 426 426 ILE ILE B . n 
B 1 427 ASP 427 427 427 ASP ASP B . n 
B 1 428 SER 428 428 428 SER SER B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 GLY 430 430 430 GLY GLY B . n 
B 1 431 TYR 431 431 431 TYR TYR B . n 
B 1 432 ALA 432 432 432 ALA ALA B . n 
B 1 433 TRP 433 433 433 TRP TRP B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 ASP 435 435 435 ASP ASP B . n 
B 1 436 GLN 436 436 436 GLN GLN B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 LEU 438 438 438 LEU LEU B . n 
B 1 439 LEU 439 439 439 LEU LEU B . n 
B 1 440 GLU 440 440 440 GLU GLU B . n 
B 1 441 VAL 441 441 441 VAL VAL B . n 
B 1 442 VAL 442 442 442 VAL VAL B . n 
B 1 443 ASN 443 443 443 ASN ASN B . n 
B 1 444 ARG 444 444 444 ARG ARG B . n 
B 1 445 PHE 445 445 445 PHE PHE B . n 
B 1 446 ARG 446 446 446 ARG ARG B . n 
B 1 447 GLU 447 447 447 GLU GLU B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 LYS 450 450 450 LYS LYS B . n 
B 1 451 PRO 451 451 451 PRO PRO B . n 
B 1 452 ASP 452 452 452 ASP ASP B . n 
B 1 453 GLN 453 453 453 GLN GLN B . n 
B 1 454 TYR 454 454 454 TYR TYR B . n 
B 1 455 LEU 455 455 455 LEU LEU B . n 
B 1 456 CYS 456 456 456 CYS CYS B . n 
B 1 457 ARG 457 457 457 ARG ARG B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 GLY 460 460 460 GLY GLY B . n 
B 1 461 THR 461 461 461 THR THR B . n 
B 1 462 GLN 462 462 462 GLN GLN B . n 
B 1 463 PHE 463 463 463 PHE PHE B . n 
B 1 464 VAL 464 464 464 VAL VAL B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 VAL 466 466 466 VAL VAL B . n 
B 1 467 SER 467 467 467 SER SER B . n 
B 1 468 LEU 468 468 468 LEU LEU B . n 
B 1 469 GLU 469 469 469 GLU GLU B . n 
B 1 470 ASN 470 470 470 ASN ASN B . n 
B 1 471 ASP 471 471 471 ASP ASP B . n 
B 1 472 VAL 472 472 472 VAL VAL B . n 
B 1 473 SER 473 473 473 SER SER B . n 
B 1 474 ASN 474 474 474 ASN ASN B . n 
B 1 475 ILE 475 475 475 ILE ILE B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 GLN 477 477 477 GLN GLN B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 ALA 479 479 479 ALA ALA B . n 
B 1 480 ASP 480 480 480 ASP ASP B . n 
B 1 481 GLU 481 481 481 GLU GLU B . n 
B 1 482 LEU 482 482 482 LEU LEU B . n 
B 1 483 ARG 483 483 483 ARG ARG B . n 
B 1 484 ASN 484 484 484 ASN ASN B . n 
B 1 485 VAL 485 485 485 VAL VAL B . n 
B 1 486 VAL 486 486 486 VAL VAL B . n 
B 1 487 SER 487 487 487 SER SER B . n 
B 1 488 LYS 488 488 488 LYS LYS B . n 
B 1 489 PRO 489 489 489 PRO PRO B . n 
B 1 490 ILE 490 490 490 ILE ILE B . n 
B 1 491 MET 491 491 491 MET MET B . n 
B 1 492 ILE 492 492 492 ILE ILE B . n 
B 1 493 ASP 493 493 493 ASP ASP B . n 
B 1 494 ASP 494 494 494 ASP ASP B . n 
B 1 495 LYS 495 495 495 LYS LYS B . n 
B 1 496 PRO 496 496 496 PRO PRO B . n 
B 1 497 PHE 497 497 497 PHE PHE B . n 
B 1 498 PRO 498 498 498 PRO PRO B . n 
B 1 499 LEU 499 499 499 LEU LEU B . n 
B 1 500 THR 500 500 500 THR THR B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 SER 502 502 502 SER SER B . n 
B 1 503 ILE 503 503 503 ILE ILE B . n 
B 1 504 GLY 504 504 504 GLY GLY B . n 
B 1 505 ILE 505 505 505 ILE ILE B . n 
B 1 506 SER 506 506 506 SER SER B . n 
B 1 507 TYR 507 507 507 TYR TYR B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 LEU 509 509 509 LEU LEU B . n 
B 1 510 GLY 510 510 510 GLY GLY B . n 
B 1 511 LYS 511 511 511 LYS LYS B . n 
B 1 512 ASN 512 512 512 ASN ASN B . n 
B 1 513 ARG 513 513 513 ARG ARG B . n 
B 1 514 ASP 514 514 514 ASP ASP B . n 
B 1 515 TYR 515 515 515 TYR TYR B . n 
B 1 516 LEU 516 516 516 LEU LEU B . n 
B 1 517 LEU 517 517 517 LEU LEU B . n 
B 1 518 SER 518 518 518 SER SER B . n 
B 1 519 THR 519 519 519 THR THR B . n 
B 1 520 ALA 520 520 520 ALA ALA B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 ASN 522 522 522 ASN ASN B . n 
B 1 523 ALA 523 523 523 ALA ALA B . n 
B 1 524 MET 524 524 524 MET MET B . n 
B 1 525 ASP 525 525 525 ASP ASP B . n 
B 1 526 TYR 526 526 526 TYR TYR B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 ARG 528 528 528 ARG ARG B . n 
B 1 529 LYS 529 529 529 LYS LYS B . n 
B 1 530 ASN 530 530 530 ASN ASN B . n 
B 1 531 GLY 531 531 531 GLY GLY B . n 
B 1 532 GLY 532 532 532 GLY GLY B . n 
B 1 533 ASN 533 533 533 ASN ASN B . n 
B 1 534 GLY 534 534 534 GLY GLY B . n 
B 1 535 TRP 535 535 535 TRP TRP B . n 
B 1 536 GLN 536 536 536 GLN GLN B . n 
B 1 537 PHE 537 537 537 PHE PHE B . n 
B 1 538 PHE 538 538 538 PHE PHE B . n 
B 1 539 SER 539 539 539 SER SER B . n 
B 1 540 PRO 540 540 540 PRO PRO B . n 
B 1 541 ALA 541 541 541 ALA ALA B . n 
B 1 542 MET 542 542 542 MET MET B . n 
B 1 543 ASN 543 543 543 ASN ASN B . n 
B 1 544 GLU 544 544 544 GLU GLU B . n 
B 1 545 MET 545 545 545 MET MET B . n 
B 1 546 VAL 546 546 546 VAL VAL B . n 
B 1 547 LYS 547 547 547 LYS LYS B . n 
B 1 548 GLU 548 548 548 GLU GLU B . n 
B 1 549 ARG 549 549 549 ARG ARG B . n 
B 1 550 LEU 550 550 550 LEU LEU B . n 
B 1 551 VAL 551 551 551 VAL VAL B . n 
B 1 552 LEU 552 552 552 LEU LEU B . n 
B 1 553 GLY 553 553 553 GLY GLY B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 ALA 555 555 555 ALA ALA B . n 
B 1 556 LEU 556 556 556 LEU LEU B . n 
B 1 557 LYS 557 557 557 LYS LYS B . n 
B 1 558 GLU 558 558 558 GLU GLU B . n 
B 1 559 ALA 559 559 559 ALA ALA B . n 
B 1 560 ILE 560 560 560 ILE ILE B . n 
B 1 561 SER 561 561 561 SER SER B . n 
B 1 562 ASN 562 562 562 ASN ASN B . n 
B 1 563 ASN 563 563 563 ASN ASN B . n 
B 1 564 GLN 564 564 564 GLN GLN B . n 
B 1 565 LEU 565 565 565 LEU LEU B . n 
B 1 566 LYS 566 566 566 LYS LYS B . n 
B 1 567 LEU 567 567 567 LEU LEU B . n 
B 1 568 VAL 568 568 568 VAL VAL B . n 
B 1 569 TYR 569 569 569 TYR TYR B . n 
B 1 570 GLN 570 570 570 GLN GLN B . n 
B 1 571 PRO 571 571 571 PRO PRO B . n 
B 1 572 GLN 572 572 572 GLN GLN B . n 
B 1 573 ILE 573 573 573 ILE ILE B . n 
B 1 574 PHE 574 574 574 PHE PHE B . n 
B 1 575 ALA 575 575 575 ALA ALA B . n 
B 1 576 GLU 576 576 576 GLU GLU B . n 
B 1 577 THR 577 577 577 THR THR B . n 
B 1 578 GLY 578 578 578 GLY GLY B . n 
B 1 579 GLU 579 579 579 GLU GLU B . n 
B 1 580 LEU 580 580 580 LEU LEU B . n 
B 1 581 TYR 581 581 581 TYR TYR B . n 
B 1 582 GLY 582 582 582 GLY GLY B . n 
B 1 583 ILE 583 583 583 ILE ILE B . n 
B 1 584 GLU 584 584 584 GLU GLU B . n 
B 1 585 ALA 585 585 585 ALA ALA B . n 
B 1 586 LEU 586 586 586 LEU LEU B . n 
B 1 587 ALA 587 587 587 ALA ALA B . n 
B 1 588 ARG 588 588 588 ARG ARG B . n 
B 1 589 TRP 589 589 589 TRP TRP B . n 
B 1 590 HIS 590 590 590 HIS HIS B . n 
B 1 591 ASP 591 591 591 ASP ASP B . n 
B 1 592 PRO 592 592 592 PRO PRO B . n 
B 1 593 LEU 593 593 593 LEU LEU B . n 
B 1 594 HIS 594 594 594 HIS HIS B . n 
B 1 595 GLY 595 595 595 GLY GLY B . n 
B 1 596 HIS 596 596 596 HIS HIS B . n 
B 1 597 VAL 597 597 597 VAL VAL B . n 
B 1 598 PRO 598 598 598 PRO PRO B . n 
B 1 599 PRO 599 599 599 PRO PRO B . n 
B 1 600 SER 600 600 600 SER SER B . n 
B 1 601 ARG 601 601 601 ARG ARG B . n 
B 1 602 PHE 602 602 602 PHE PHE B . n 
B 1 603 ILE 603 603 603 ILE ILE B . n 
B 1 604 PRO 604 604 604 PRO PRO B . n 
B 1 605 LEU 605 605 605 LEU LEU B . n 
B 1 606 ALA 606 606 606 ALA ALA B . n 
B 1 607 GLU 607 607 607 GLU GLU B . n 
B 1 608 GLU 608 608 608 GLU GLU B . n 
B 1 609 ILE 609 609 609 ILE ILE B . n 
B 1 610 GLY 610 610 610 GLY GLY B . n 
B 1 611 GLU 611 611 611 GLU GLU B . n 
B 1 612 ILE 612 612 612 ILE ILE B . n 
B 1 613 GLU 613 613 613 GLU GLU B . n 
B 1 614 ASN 614 614 614 ASN ASN B . n 
B 1 615 ILE 615 615 615 ILE ILE B . n 
B 1 616 GLY 616 616 616 GLY GLY B . n 
B 1 617 ARG 617 617 617 ARG ARG B . n 
B 1 618 TRP 618 618 618 TRP TRP B . n 
B 1 619 VAL 619 619 619 VAL VAL B . n 
B 1 620 ILE 620 620 620 ILE ILE B . n 
B 1 621 ALA 621 621 621 ALA ALA B . n 
B 1 622 GLU 622 622 622 GLU GLU B . n 
B 1 623 ALA 623 623 623 ALA ALA B . n 
B 1 624 CYS 624 624 624 CYS CYS B . n 
B 1 625 ARG 625 625 625 ARG ARG B . n 
B 1 626 GLN 626 626 626 GLN GLN B . n 
B 1 627 LEU 627 627 627 LEU LEU B . n 
B 1 628 ALA 628 628 628 ALA ALA B . n 
B 1 629 GLU 629 629 629 GLU GLU B . n 
B 1 630 TRP 630 630 630 TRP TRP B . n 
B 1 631 ARG 631 631 631 ARG ARG B . n 
B 1 632 SER 632 632 632 SER SER B . n 
B 1 633 GLN 633 633 633 GLN GLN B . n 
B 1 634 ASN 634 634 634 ASN ASN B . n 
B 1 635 ILE 635 635 635 ILE ILE B . n 
B 1 636 HIS 636 636 636 HIS HIS B . n 
B 1 637 ILE 637 637 637 ILE ILE B . n 
B 1 638 PRO 638 638 638 PRO PRO B . n 
B 1 639 ALA 639 639 639 ALA ALA B . n 
B 1 640 LEU 640 640 640 LEU LEU B . n 
B 1 641 SER 641 641 641 SER SER B . n 
B 1 642 VAL 642 642 642 VAL VAL B . n 
B 1 643 ASN 643 643 643 ASN ASN B . n 
B 1 644 LEU 644 644 644 LEU LEU B . n 
B 1 645 SER 645 645 645 SER SER B . n 
B 1 646 ALA 646 646 646 ALA ALA B . n 
B 1 647 LEU 647 647 647 LEU LEU B . n 
B 1 648 HIS 648 648 648 HIS HIS B . n 
B 1 649 PHE 649 649 649 PHE PHE B . n 
B 1 650 ARG 650 650 650 ARG ARG B . n 
B 1 651 SER 651 651 651 SER SER B . n 
B 1 652 ASN 652 652 652 ASN ASN B . n 
B 1 653 GLN 653 653 653 GLN GLN B . n 
B 1 654 LEU 654 654 654 LEU LEU B . n 
B 1 655 PRO 655 655 655 PRO PRO B . n 
B 1 656 ASN 656 656 656 ASN ASN B . n 
B 1 657 GLN 657 657 657 GLN GLN B . n 
B 1 658 VAL 658 658 658 VAL VAL B . n 
B 1 659 SER 659 659 659 SER SER B . n 
B 1 660 ASP 660 660 660 ASP ASP B . n 
B 1 661 ALA 661 661 661 ALA ALA B . n 
B 1 662 MET 662 662 662 MET MET B . n 
B 1 663 HIS 663 663 663 HIS HIS B . n 
B 1 664 ALA 664 664 664 ALA ALA B . n 
B 1 665 TRP 665 665 665 TRP TRP B . n 
B 1 666 GLY 666 666 666 GLY GLY B . n 
B 1 667 ILE 667 667 667 ILE ILE B . n 
B 1 668 ASP 668 668 668 ASP ASP B . n 
B 1 669 GLY 669 669 669 GLY GLY B . n 
B 1 670 HIS 670 670 670 HIS HIS B . n 
B 1 671 GLN 671 671 671 GLN GLN B . n 
B 1 672 LEU 672 672 672 LEU LEU B . n 
B 1 673 THR 673 673 673 THR THR B . n 
B 1 674 VAL 674 674 674 VAL VAL B . n 
B 1 675 GLU 675 675 675 GLU GLU B . n 
B 1 676 ILE 676 676 676 ILE ILE B . n 
B 1 677 THR 677 677 677 THR THR B . n 
B 1 678 GLU 678 678 678 GLU GLU B . n 
B 1 679 SER 679 679 679 SER SER B . n 
B 1 680 MET 680 680 680 MET MET B . n 
B 1 681 MET 681 681 681 MET MET B . n 
B 1 682 MET 682 682 682 MET MET B . n 
B 1 683 GLU 683 683 683 GLU GLU B . n 
B 1 684 HIS 684 684 684 HIS HIS B . n 
B 1 685 ASP 685 685 685 ASP ASP B . n 
B 1 686 THR 686 686 686 THR THR B . n 
B 1 687 GLU 687 687 687 GLU GLU B . n 
B 1 688 ILE 688 688 688 ILE ILE B . n 
B 1 689 PHE 689 689 689 PHE PHE B . n 
B 1 690 LYS 690 690 690 LYS LYS B . n 
B 1 691 ARG 691 691 691 ARG ARG B . n 
B 1 692 ILE 692 692 692 ILE ILE B . n 
B 1 693 GLN 693 693 693 GLN GLN B . n 
B 1 694 ILE 694 694 694 ILE ILE B . n 
B 1 695 LEU 695 695 695 LEU LEU B . n 
B 1 696 ARG 696 696 696 ARG ARG B . n 
B 1 697 ASP 697 697 697 ASP ASP B . n 
B 1 698 MET 698 698 698 MET MET B . n 
B 1 699 GLY 699 699 699 GLY GLY B . n 
B 1 700 VAL 700 700 700 VAL VAL B . n 
B 1 701 GLY 701 701 701 GLY GLY B . n 
B 1 702 LEU 702 702 702 LEU LEU B . n 
B 1 703 SER 703 703 703 SER SER B . n 
B 1 704 VAL 704 704 704 VAL VAL B . n 
B 1 705 ASP 705 705 705 ASP ASP B . n 
B 1 706 ASP 706 706 706 ASP ASP B . n 
B 1 707 PHE 707 707 707 PHE PHE B . n 
B 1 708 GLY 708 708 708 GLY GLY B . n 
B 1 709 THR 709 709 709 THR THR B . n 
B 1 710 GLY 710 710 710 GLY GLY B . n 
B 1 711 PHE 711 711 711 PHE PHE B . n 
B 1 712 SER 712 712 712 SER SER B . n 
B 1 713 GLY 713 713 713 GLY GLY B . n 
B 1 714 LEU 714 714 714 LEU LEU B . n 
B 1 715 SER 715 715 715 SER SER B . n 
B 1 716 ARG 716 716 716 ARG ARG B . n 
B 1 717 LEU 717 717 717 LEU LEU B . n 
B 1 718 VAL 718 718 718 VAL VAL B . n 
B 1 719 SER 719 719 719 SER SER B . n 
B 1 720 LEU 720 720 720 LEU LEU B . n 
B 1 721 PRO 721 721 721 PRO PRO B . n 
B 1 722 VAL 722 722 722 VAL VAL B . n 
B 1 723 THR 723 723 723 THR THR B . n 
B 1 724 GLU 724 724 724 GLU GLU B . n 
B 1 725 ILE 725 725 725 ILE ILE B . n 
B 1 726 LYS 726 726 726 LYS LYS B . n 
B 1 727 ILE 727 727 727 ILE ILE B . n 
B 1 728 ASP 728 728 728 ASP ASP B . n 
B 1 729 LYS 729 729 729 LYS LYS B . n 
B 1 730 SER 730 730 730 SER SER B . n 
B 1 731 PHE 731 731 731 PHE PHE B . n 
B 1 732 VAL 732 732 732 VAL VAL B . n 
B 1 733 ASP 733 733 733 ASP ASP B . n 
B 1 734 ARG 734 734 734 ARG ARG B . n 
B 1 735 CYS 735 735 735 CYS CYS B . n 
B 1 736 LEU 736 736 736 LEU LEU B . n 
B 1 737 THR 737 737 737 THR THR B . n 
B 1 738 GLU 738 738 738 GLU GLU B . n 
B 1 739 LYS 739 739 739 LYS LYS B . n 
B 1 740 ARG 740 740 740 ARG ARG B . n 
B 1 741 ILE 741 741 741 ILE ILE B . n 
B 1 742 LEU 742 742 742 LEU LEU B . n 
B 1 743 ALA 743 743 743 ALA ALA B . n 
B 1 744 LEU 744 744 744 LEU LEU B . n 
B 1 745 LEU 745 745 745 LEU LEU B . n 
B 1 746 GLU 746 746 746 GLU GLU B . n 
B 1 747 ALA 747 747 747 ALA ALA B . n 
B 1 748 ILE 748 748 748 ILE ILE B . n 
B 1 749 THR 749 749 749 THR THR B . n 
B 1 750 SER 750 750 750 SER SER B . n 
B 1 751 ILE 751 751 751 ILE ILE B . n 
B 1 752 GLY 752 752 752 GLY GLY B . n 
B 1 753 GLN 753 753 753 GLN GLN B . n 
B 1 754 SER 754 754 754 SER SER B . n 
B 1 755 LEU 755 755 755 LEU LEU B . n 
B 1 756 ASN 756 756 756 ASN ASN B . n 
B 1 757 LEU 757 757 757 LEU LEU B . n 
B 1 758 THR 758 758 758 THR THR B . n 
B 1 759 VAL 759 759 759 VAL VAL B . n 
B 1 760 VAL 760 760 760 VAL VAL B . n 
B 1 761 ALA 761 761 761 ALA ALA B . n 
B 1 762 GLU 762 762 762 GLU GLU B . n 
B 1 763 GLY 763 763 763 GLY GLY B . n 
B 1 764 VAL 764 764 764 VAL VAL B . n 
B 1 765 GLU 765 765 765 GLU GLU B . n 
B 1 766 THR 766 766 766 THR THR B . n 
B 1 767 LYS 767 767 767 LYS LYS B . n 
B 1 768 GLU 768 768 768 GLU GLU B . n 
B 1 769 GLN 769 769 769 GLN GLN B . n 
B 1 770 PHE 770 770 770 PHE PHE B . n 
B 1 771 GLU 771 771 771 GLU GLU B . n 
B 1 772 MET 772 772 772 MET MET B . n 
B 1 773 LEU 773 773 773 LEU LEU B . n 
B 1 774 ARG 774 774 774 ARG ARG B . n 
B 1 775 LYS 775 775 775 LYS LYS B . n 
B 1 776 ILE 776 776 776 ILE ILE B . n 
B 1 777 HIS 777 777 777 HIS HIS B . n 
B 1 778 CYS 778 778 778 CYS CYS B . n 
B 1 779 ARG 779 779 779 ARG ARG B . n 
B 1 780 VAL 780 780 780 VAL VAL B . n 
B 1 781 ILE 781 781 781 ILE ILE B . n 
B 1 782 GLN 782 782 782 GLN GLN B . n 
B 1 783 GLY 783 783 783 GLY GLY B . n 
B 1 784 TYR 784 784 784 TYR TYR B . n 
B 1 785 PHE 785 785 785 PHE PHE B . n 
B 1 786 PHE 786 786 786 PHE PHE B . n 
B 1 787 SER 787 787 787 SER SER B . n 
B 1 788 ARG 788 788 788 ARG ARG B . n 
B 1 789 PRO 789 789 789 PRO PRO B . n 
B 1 790 LEU 790 790 790 LEU LEU B . n 
B 1 791 PRO 791 791 791 PRO PRO B . n 
B 1 792 ALA 792 792 792 ALA ALA B . n 
B 1 793 GLU 793 793 793 GLU GLU B . n 
B 1 794 GLU 794 794 794 GLU GLU B . n 
B 1 795 ILE 795 795 795 ILE ILE B . n 
B 1 796 PRO 796 796 796 PRO PRO B . n 
B 1 797 GLY 797 797 797 GLY GLY B . n 
B 1 798 TRP 798 798 798 TRP TRP B . n 
B 1 799 MET 799 799 799 MET MET B . n 
B 1 800 SER 800 800 800 SER SER B . n 
B 1 801 SER 801 801 801 SER SER B . n 
B 1 802 VAL 802 802 802 VAL VAL B . n 
B 1 803 LEU 803 803 803 LEU LEU B . n 
B 1 804 PRO 804 804 804 PRO PRO B . n 
B 1 805 LEU 805 805 805 LEU LEU B . n 
B 1 806 LYS 806 806 806 LYS LYS B . n 
B 1 807 ILE 807 807 807 ILE ILE B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HEM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HEM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 HEM 1 901 2135 HEM HEM A . 
D 2 HEM 1 901 2135 HEM HEM B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BKV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BKV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BKV 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BKV 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 12832 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.813 ? 17414 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 6.255 ? 1710  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.048 ? 1927  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 2265  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BKV 
_struct.title                        'DosP R97A bent form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BKV 
_struct_keywords.text            'Heme, DosP, Phosphodiesterase, c-di-GMP, OXYGEN BINDING' 
_struct_keywords.pdbx_keywords   'OXYGEN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    DOSP_ECOLI 
_struct_ref.pdbx_db_accession          P76129 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGG
KARVEGMSRELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVYDVLAHLQN
LVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEIQNAQSWS
ATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHNYLDDLVDK
AVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIADELRNVVSK
PIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLV
YQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALH
FRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKID
KSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLKI
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BKV A 9 ? 807 ? P76129 1 ? 799 ? 9 807 
2 1 9BKV B 9 ? 807 ? P76129 1 ? 799 ? 9 807 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BKV MET A 1   ? UNP P76129 ?   ?   'expression tag'      1   1  
1 9BKV ARG A 2   ? UNP P76129 ?   ?   'expression tag'      2   2  
1 9BKV GLN A 3   ? UNP P76129 ?   ?   'expression tag'      3   3  
1 9BKV ASP A 4   ? UNP P76129 ?   ?   'expression tag'      4   4  
1 9BKV ALA A 5   ? UNP P76129 ?   ?   'expression tag'      5   5  
1 9BKV GLU A 6   ? UNP P76129 ?   ?   'expression tag'      6   6  
1 9BKV VAL A 7   ? UNP P76129 ?   ?   'expression tag'      7   7  
1 9BKV ILE A 8   ? UNP P76129 ?   ?   'expression tag'      8   8  
1 9BKV SER A 16  ? UNP P76129 ASN 8   conflict              16  9  
1 9BKV ALA A 97  ? UNP P76129 ARG 89  'engineered mutation' 97  10 
1 9BKV THR A 195 ? UNP P76129 ILE 187 conflict              195 11 
2 9BKV MET B 1   ? UNP P76129 ?   ?   'expression tag'      1   12 
2 9BKV ARG B 2   ? UNP P76129 ?   ?   'expression tag'      2   13 
2 9BKV GLN B 3   ? UNP P76129 ?   ?   'expression tag'      3   14 
2 9BKV ASP B 4   ? UNP P76129 ?   ?   'expression tag'      4   15 
2 9BKV ALA B 5   ? UNP P76129 ?   ?   'expression tag'      5   16 
2 9BKV GLU B 6   ? UNP P76129 ?   ?   'expression tag'      6   17 
2 9BKV VAL B 7   ? UNP P76129 ?   ?   'expression tag'      7   18 
2 9BKV ILE B 8   ? UNP P76129 ?   ?   'expression tag'      8   19 
2 9BKV SER B 16  ? UNP P76129 ASN 8   conflict              16  20 
2 9BKV ALA B 97  ? UNP P76129 ARG 89  'engineered mutation' 97  21 
2 9BKV THR B 195 ? UNP P76129 ILE 187 conflict              195 22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ILE A 21  ? ASN A 29  ? ILE A 21  ASN A 29  1 ? 9  
HELX_P HELX_P2  AA2 ASN A 46  ? TRP A 53  ? ASN A 46  TRP A 53  1 ? 8  
HELX_P HELX_P3  AA3 LYS A 56  ? ILE A 61  ? LYS A 56  ILE A 61  1 ? 6  
HELX_P HELX_P4  AA4 ASN A 64  ? ILE A 69  ? ASN A 64  ILE A 69  5 ? 6  
HELX_P HELX_P5  AA5 PRO A 70  ? HIS A 77  ? PRO A 70  HIS A 77  5 ? 8  
HELX_P HELX_P6  AA6 PRO A 78  ? GLY A 88  ? PRO A 78  GLY A 88  1 ? 11 
HELX_P HELX_P7  AA7 ALA A 133 ? HIS A 152 ? ALA A 133 HIS A 152 1 ? 20 
HELX_P HELX_P8  AA8 ASN A 170 ? GLU A 175 ? ASN A 170 GLU A 175 1 ? 6  
HELX_P HELX_P9  AA9 GLN A 188 ? LEU A 193 ? GLN A 188 LEU A 193 1 ? 6  
HELX_P HELX_P10 AB1 PRO A 199 ? LYS A 212 ? PRO A 199 LYS A 212 1 ? 14 
HELX_P HELX_P11 AB2 THR A 257 ? SER A 276 ? THR A 257 SER A 276 1 ? 20 
HELX_P HELX_P12 AB3 PRO A 278 ? LEU A 294 ? PRO A 278 LEU A 294 1 ? 17 
HELX_P HELX_P13 AB4 THR A 352 ? GLN A 382 ? THR A 352 GLN A 382 1 ? 31 
HELX_P HELX_P14 AB5 ASN A 394 ? LYS A 408 ? ASN A 394 LYS A 408 1 ? 15 
HELX_P HELX_P15 AB6 HIS A 421 ? GLY A 430 ? HIS A 421 GLY A 430 1 ? 10 
HELX_P HELX_P16 AB7 GLY A 430 ? GLU A 447 ? GLY A 430 GLU A 447 1 ? 18 
HELX_P HELX_P17 AB8 ASP A 471 ? VAL A 485 ? ASP A 471 VAL A 485 1 ? 15 
HELX_P HELX_P18 AB9 ASN A 512 ? ASN A 530 ? ASN A 512 ASN A 530 1 ? 19 
HELX_P HELX_P19 AC1 SER A 539 ? ASN A 563 ? SER A 539 ASN A 563 1 ? 25 
HELX_P HELX_P20 AC2 PRO A 598 ? GLY A 610 ? PRO A 598 GLY A 610 1 ? 13 
HELX_P HELX_P21 AC3 GLU A 611 ? ARG A 631 ? GLU A 611 ARG A 631 1 ? 21 
HELX_P HELX_P22 AC4 GLN A 653 ? TRP A 665 ? GLN A 653 TRP A 665 1 ? 13 
HELX_P HELX_P23 AC5 ILE A 688 ? MET A 698 ? ILE A 688 MET A 698 1 ? 11 
HELX_P HELX_P24 AC6 GLY A 710 ? LEU A 720 ? GLY A 710 LEU A 720 1 ? 11 
HELX_P HELX_P25 AC7 ASP A 728 ? ASP A 733 ? ASP A 728 ASP A 733 1 ? 6  
HELX_P HELX_P26 AC8 LYS A 739 ? ASN A 756 ? LYS A 739 ASN A 756 1 ? 18 
HELX_P HELX_P27 AC9 THR A 766 ? ILE A 776 ? THR A 766 ILE A 776 1 ? 11 
HELX_P HELX_P28 AD1 ILE A 795 ? SER A 800 ? ILE A 795 SER A 800 1 ? 6  
HELX_P HELX_P29 AD2 ILE B 21  ? ASN B 29  ? ILE B 21  ASN B 29  1 ? 9  
HELX_P HELX_P30 AD3 ASN B 46  ? GLY B 54  ? ASN B 46  GLY B 54  1 ? 9  
HELX_P HELX_P31 AD4 LYS B 56  ? ILE B 61  ? LYS B 56  ILE B 61  1 ? 6  
HELX_P HELX_P32 AD5 PRO B 75  ? GLY B 88  ? PRO B 75  GLY B 88  1 ? 14 
HELX_P HELX_P33 AD6 SER B 134 ? ALA B 149 ? SER B 134 ALA B 149 1 ? 16 
HELX_P HELX_P34 AD7 ASN B 170 ? GLY B 178 ? ASN B 170 GLY B 178 1 ? 9  
HELX_P HELX_P35 AD8 CYS B 180 ? SER B 185 ? CYS B 180 SER B 185 1 ? 6  
HELX_P HELX_P36 AD9 GLN B 188 ? LEU B 193 ? GLN B 188 LEU B 193 1 ? 6  
HELX_P HELX_P37 AE1 ALA B 200 ? LYS B 212 ? ALA B 200 LYS B 212 1 ? 13 
HELX_P HELX_P38 AE2 GLU B 258 ? CYS B 274 ? GLU B 258 CYS B 274 1 ? 17 
HELX_P HELX_P39 AE3 PRO B 278 ? LEU B 294 ? PRO B 278 LEU B 294 1 ? 17 
HELX_P HELX_P40 AE4 THR B 352 ? GLN B 378 ? THR B 352 GLN B 378 1 ? 27 
HELX_P HELX_P41 AE5 ASN B 394 ? ASP B 407 ? ASN B 394 ASP B 407 1 ? 14 
HELX_P HELX_P42 AE6 ILE B 422 ? GLY B 430 ? ILE B 422 GLY B 430 1 ? 9  
HELX_P HELX_P43 AE7 GLY B 430 ? LYS B 448 ? GLY B 430 LYS B 448 1 ? 19 
HELX_P HELX_P44 AE8 ASP B 471 ? VAL B 486 ? ASP B 471 VAL B 486 1 ? 16 
HELX_P HELX_P45 AE9 ASN B 512 ? GLY B 531 ? ASN B 512 GLY B 531 1 ? 20 
HELX_P HELX_P46 AF1 SER B 539 ? ASN B 562 ? SER B 539 ASN B 562 1 ? 24 
HELX_P HELX_P47 AF2 PRO B 598 ? GLY B 610 ? PRO B 598 GLY B 610 1 ? 13 
HELX_P HELX_P48 AF3 GLU B 611 ? ASN B 634 ? GLU B 611 ASN B 634 1 ? 24 
HELX_P HELX_P49 AF4 GLN B 653 ? TRP B 665 ? GLN B 653 TRP B 665 1 ? 13 
HELX_P HELX_P50 AF5 GLU B 678 ? GLU B 683 ? GLU B 678 GLU B 683 1 ? 6  
HELX_P HELX_P51 AF6 THR B 686 ? GLY B 699 ? THR B 686 GLY B 699 1 ? 14 
HELX_P HELX_P52 AF7 THR B 709 ? LEU B 720 ? THR B 709 LEU B 720 1 ? 12 
HELX_P HELX_P53 AF8 ASP B 728 ? ASP B 733 ? ASP B 728 ASP B 733 1 ? 6  
HELX_P HELX_P54 AF9 GLU B 738 ? LEU B 755 ? GLU B 738 LEU B 755 1 ? 18 
HELX_P HELX_P55 AG1 THR B 766 ? ILE B 776 ? THR B 766 ILE B 776 1 ? 11 
HELX_P HELX_P56 AG2 GLU B 794 ? VAL B 802 ? GLU B 794 VAL B 802 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            metalc1 
_struct_conn.conn_type_id                  metalc 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           HIS 
_struct_conn.ptnr1_label_seq_id            77 
_struct_conn.ptnr1_label_atom_id           NE2 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           D 
_struct_conn.ptnr2_label_comp_id           HEM 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           FE 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            B 
_struct_conn.ptnr1_auth_comp_id            HIS 
_struct_conn.ptnr1_auth_seq_id             77 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            HEM 
_struct_conn.ptnr2_auth_seq_id             901 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.375 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NA ? D HEM . ? B HEM 901 ? 1_555 106.5 ? 
2  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NB ? D HEM . ? B HEM 901 ? 1_555 76.8  ? 
3  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NB ? D HEM . ? B HEM 901 ? 1_555 87.6  ? 
4  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 78.9  ? 
5  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 174.5 ? 
6  NB  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 92.7  ? 
7  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 110.7 ? 
8  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 91.3  ? 
9  NB  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 172.3 ? 
10 NC  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 87.6  ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          PHE 
_struct_mon_prot_cis.label_seq_id           198 
_struct_mon_prot_cis.label_asym_id          B 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           PHE 
_struct_mon_prot_cis.auth_seq_id            198 
_struct_mon_prot_cis.auth_asym_id           B 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    199 
_struct_mon_prot_cis.pdbx_label_asym_id_2   B 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     199 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    B 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       4.36 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4  ? 
AA2 ? 3  ? 
AA3 ? 3  ? 
AA4 ? 4  ? 
AA5 ? 4  ? 
AA6 ? 5  ? 
AA7 ? 2  ? 
AA8 ? 4  ? 
AA9 ? 10 ? 
AB1 ? 5  ? 
AB2 ? 5  ? 
AB3 ? 4  ? 
AB4 ? 5  ? 
AB5 ? 2  ? 
AB6 ? 4  ? 
AB7 ? 6  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA5 1 2  ? anti-parallel 
AA5 2 3  ? anti-parallel 
AA5 3 4  ? anti-parallel 
AA6 1 2  ? anti-parallel 
AA6 2 3  ? anti-parallel 
AA6 3 4  ? anti-parallel 
AA6 4 5  ? parallel      
AA7 1 2  ? anti-parallel 
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? parallel      
AA9 3 4  ? parallel      
AA9 4 5  ? parallel      
AA9 5 6  ? parallel      
AA9 6 7  ? parallel      
AA9 7 8  ? parallel      
AA9 8 9  ? anti-parallel 
AA9 9 10 ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB1 4 5  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB2 4 5  ? anti-parallel 
AB3 1 2  ? anti-parallel 
AB3 2 3  ? anti-parallel 
AB3 3 4  ? anti-parallel 
AB4 1 2  ? anti-parallel 
AB4 2 3  ? anti-parallel 
AB4 3 4  ? anti-parallel 
AB4 4 5  ? parallel      
AB5 1 2  ? anti-parallel 
AB6 1 2  ? anti-parallel 
AB6 2 3  ? parallel      
AB6 3 4  ? parallel      
AB7 1 2  ? anti-parallel 
AB7 2 3  ? anti-parallel 
AB7 3 4  ? anti-parallel 
AB7 4 5  ? parallel      
AB7 5 6  ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  GLY A 32  ? ILE A 36  ? GLY A 32  ILE A 36  
AA1 2  LYS A 123 ? ASP A 132 ? LYS A 123 ASP A 132 
AA1 3  LYS A 108 ? ALA A 120 ? LYS A 108 ALA A 120 
AA1 4  LEU A 99  ? GLU A 102 ? LEU A 99  GLU A 102 
AA2 1  ILE A 166 ? GLN A 168 ? ILE A 166 GLN A 168 
AA2 2  VAL A 157 ? LEU A 160 ? VAL A 157 LEU A 160 
AA2 3  LEU A 249 ? THR A 252 ? LEU A 249 THR A 252 
AA3 1  GLU A 219 ? LEU A 223 ? GLU A 219 LEU A 223 
AA3 2  LYS A 229 ? LYS A 233 ? LYS A 229 LYS A 233 
AA3 3  SER A 254 ? ASP A 255 ? SER A 254 ASP A 255 
AA4 1  MET A 308 ? SER A 314 ? MET A 308 SER A 314 
AA4 2  SER A 297 ? ARG A 305 ? SER A 297 ARG A 305 
AA4 3  PRO A 338 ? SER A 347 ? PRO A 338 SER A 347 
AA4 4  ALA A 324 ? GLN A 325 ? ALA A 324 GLN A 325 
AA5 1  MET A 308 ? SER A 314 ? MET A 308 SER A 314 
AA5 2  SER A 297 ? ARG A 305 ? SER A 297 ARG A 305 
AA5 3  PRO A 338 ? SER A 347 ? PRO A 338 SER A 347 
AA5 4  SER A 328 ? ARG A 332 ? SER A 328 ARG A 332 
AA6 1  TYR A 454 ? GLU A 459 ? TYR A 454 GLU A 459 
AA6 2  GLN A 462 ? SER A 467 ? GLN A 462 SER A 467 
AA6 3  VAL A 413 ? VAL A 419 ? VAL A 413 VAL A 419 
AA6 4  LEU A 501 ? SER A 506 ? LEU A 501 SER A 506 
AA6 5  GLY A 534 ? PHE A 537 ? GLY A 534 PHE A 537 
AA7 1  ILE A 490 ? MET A 491 ? ILE A 490 MET A 491 
AA7 2  PRO A 496 ? PHE A 497 ? PRO A 496 PHE A 497 
AA8 1  GLY A 595 ? VAL A 597 ? GLY A 595 VAL A 597 
AA8 2  LEU A 580 ? ASP A 591 ? LEU A 580 ASP A 591 
AA8 3  LYS A 566 ? PHE A 574 ? LYS A 566 PHE A 574 
AA8 4  LEU A 790 ? PRO A 791 ? LEU A 790 PRO A 791 
AA9 1  GLY A 595 ? VAL A 597 ? GLY A 595 VAL A 597 
AA9 2  LEU A 580 ? ASP A 591 ? LEU A 580 ASP A 591 
AA9 3  LEU A 640 ? ASN A 643 ? LEU A 640 ASN A 643 
AA9 4  LEU A 672 ? GLU A 675 ? LEU A 672 GLU A 675 
AA9 5  GLY A 701 ? VAL A 704 ? GLY A 701 VAL A 704 
AA9 6  GLU A 724 ? ILE A 727 ? GLU A 724 ILE A 727 
AA9 7  THR A 758 ? GLU A 762 ? THR A 758 GLU A 762 
AA9 8  VAL A 780 ? GLN A 782 ? VAL A 780 GLN A 782 
AA9 9  LYS A 566 ? PHE A 574 ? LYS A 566 PHE A 574 
AA9 10 LEU A 790 ? PRO A 791 ? LEU A 790 PRO A 791 
AB1 1  VAL B 42  ? PHE B 45  ? VAL B 42  PHE B 45  
AB1 2  GLY B 32  ? ILE B 36  ? GLY B 32  ILE B 36  
AB1 3  LYS B 123 ? ARG B 131 ? LYS B 123 ARG B 131 
AB1 4  LYS B 108 ? ALA B 120 ? LYS B 108 ALA B 120 
AB1 5  LEU B 99  ? GLU B 102 ? LEU B 99  GLU B 102 
AB2 1  ILE B 166 ? CYS B 169 ? ILE B 166 CYS B 169 
AB2 2  VAL B 157 ? LEU B 160 ? VAL B 157 LEU B 160 
AB2 3  LEU B 246 ? ASP B 255 ? LEU B 246 ASP B 255 
AB2 4  LYS B 229 ? TYR B 240 ? LYS B 229 TYR B 240 
AB2 5  ASP B 216 ? LEU B 223 ? ASP B 216 LEU B 223 
AB3 1  MET B 308 ? SER B 314 ? MET B 308 SER B 314 
AB3 2  SER B 297 ? ARG B 305 ? SER B 297 ARG B 305 
AB3 3  PRO B 338 ? SER B 347 ? PRO B 338 SER B 347 
AB3 4  ALA B 324 ? ARG B 332 ? ALA B 324 ARG B 332 
AB4 1  TYR B 454 ? ARG B 457 ? TYR B 454 ARG B 457 
AB4 2  PHE B 463 ? SER B 467 ? PHE B 463 SER B 467 
AB4 3  VAL B 413 ? ASP B 420 ? VAL B 413 ASP B 420 
AB4 4  THR B 500 ? SER B 506 ? THR B 500 SER B 506 
AB4 5  GLY B 534 ? PHE B 537 ? GLY B 534 PHE B 537 
AB5 1  ILE B 490 ? MET B 491 ? ILE B 490 MET B 491 
AB5 2  PRO B 496 ? PHE B 497 ? PRO B 496 PHE B 497 
AB6 1  GLY B 595 ? VAL B 597 ? GLY B 595 VAL B 597 
AB6 2  LEU B 580 ? ASP B 591 ? LEU B 580 ASP B 591 
AB6 3  LEU B 640 ? ASN B 643 ? LEU B 640 ASN B 643 
AB6 4  LEU B 672 ? GLU B 675 ? LEU B 672 GLU B 675 
AB7 1  GLY B 595 ? VAL B 597 ? GLY B 595 VAL B 597 
AB7 2  LEU B 580 ? ASP B 591 ? LEU B 580 ASP B 591 
AB7 3  LYS B 566 ? PHE B 574 ? LYS B 566 PHE B 574 
AB7 4  VAL B 780 ? GLY B 783 ? VAL B 780 GLY B 783 
AB7 5  THR B 758 ? VAL B 764 ? THR B 758 VAL B 764 
AB7 6  GLU B 724 ? ILE B 727 ? GLU B 724 ILE B 727 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  N VAL A 34  ? N VAL A 34  O ALA A 128 ? O ALA A 128 
AA1 2 3  O TYR A 125 ? O TYR A 125 N VAL A 118 ? N VAL A 118 
AA1 3 4  O ILE A 109 ? O ILE A 109 N LEU A 101 ? N LEU A 101 
AA2 1 2  O GLN A 168 ? O GLN A 168 N VAL A 159 ? N VAL A 159 
AA2 2 3  N ILE A 158 ? N ILE A 158 O MET A 251 ? O MET A 251 
AA3 1 2  N PHE A 220 ? N PHE A 220 O ILE A 232 ? O ILE A 232 
AA3 2 3  N LYS A 233 ? N LYS A 233 O SER A 254 ? O SER A 254 
AA4 1 2  O ILE A 310 ? O ILE A 310 N ALA A 303 ? N ALA A 303 
AA4 2 3  N LEU A 304 ? N LEU A 304 O ALA A 339 ? O ALA A 339 
AA4 3 4  O THR A 346 ? O THR A 346 N GLN A 325 ? N GLN A 325 
AA5 1 2  O ILE A 310 ? O ILE A 310 N ALA A 303 ? N ALA A 303 
AA5 2 3  N LEU A 304 ? N LEU A 304 O ALA A 339 ? O ALA A 339 
AA5 3 4  O ALA A 339 ? O ALA A 339 N ILE A 331 ? N ILE A 331 
AA6 1 2  N CYS A 456 ? N CYS A 456 O VAL A 464 ? O VAL A 464 
AA6 2 3  O LEU A 465 ? O LEU A 465 N TYR A 415 ? N TYR A 415 
AA6 3 4  N VAL A 414 ? N VAL A 414 O SER A 506 ? O SER A 506 
AA6 4 5  N ILE A 505 ? N ILE A 505 O GLN A 536 ? O GLN A 536 
AA7 1 2  N ILE A 490 ? N ILE A 490 O PHE A 497 ? O PHE A 497 
AA8 1 2  O GLY A 595 ? O GLY A 595 N ASP A 591 ? N ASP A 591 
AA8 2 3  O GLU A 584 ? O GLU A 584 N GLN A 570 ? N GLN A 570 
AA8 3 4  N TYR A 569 ? N TYR A 569 O LEU A 790 ? O LEU A 790 
AA9 1 2  O GLY A 595 ? O GLY A 595 N ASP A 591 ? N ASP A 591 
AA9 2 3  N ALA A 585 ? N ALA A 585 O SER A 641 ? O SER A 641 
AA9 3 4  N LEU A 640 ? N LEU A 640 O THR A 673 ? O THR A 673 
AA9 4 5  N LEU A 672 ? N LEU A 672 O GLY A 701 ? O GLY A 701 
AA9 5 6  N VAL A 704 ? N VAL A 704 O LYS A 726 ? O LYS A 726 
AA9 6 7  N ILE A 725 ? N ILE A 725 O VAL A 760 ? O VAL A 760 
AA9 7 8  N ALA A 761 ? N ALA A 761 O GLN A 782 ? O GLN A 782 
AA9 8 9  O ILE A 781 ? O ILE A 781 N ILE A 573 ? N ILE A 573 
AA9 9 10 N TYR A 569 ? N TYR A 569 O LEU A 790 ? O LEU A 790 
AB1 1 2  O PHE B 44  ? O PHE B 44  N LEU B 35  ? N LEU B 35  
AB1 2 3  N VAL B 34  ? N VAL B 34  O ALA B 128 ? O ALA B 128 
AB1 3 4  O LYS B 123 ? O LYS B 123 N ALA B 120 ? N ALA B 120 
AB1 4 5  O THR B 111 ? O THR B 111 N LEU B 99  ? N LEU B 99  
AB2 1 2  O VAL B 167 ? O VAL B 167 N VAL B 159 ? N VAL B 159 
AB2 2 3  N ILE B 158 ? N ILE B 158 O MET B 251 ? O MET B 251 
AB2 3 4  O SER B 254 ? O SER B 254 N LYS B 233 ? N LYS B 233 
AB2 4 5  O ILE B 230 ? O ILE B 230 N LEU B 222 ? N LEU B 222 
AB3 1 2  O ILE B 310 ? O ILE B 310 N ALA B 303 ? N ALA B 303 
AB3 2 3  N LEU B 304 ? N LEU B 304 O ALA B 339 ? O ALA B 339 
AB3 3 4  O GLY B 340 ? O GLY B 340 N ILE B 331 ? N ILE B 331 
AB4 1 2  N CYS B 456 ? N CYS B 456 O VAL B 464 ? O VAL B 464 
AB4 2 3  O LEU B 465 ? O LEU B 465 N TYR B 415 ? N TYR B 415 
AB4 3 4  N ASP B 420 ? N ASP B 420 O THR B 500 ? O THR B 500 
AB4 4 5  N ILE B 505 ? N ILE B 505 O GLN B 536 ? O GLN B 536 
AB5 1 2  N ILE B 490 ? N ILE B 490 O PHE B 497 ? O PHE B 497 
AB6 1 2  O GLY B 595 ? O GLY B 595 N ASP B 591 ? N ASP B 591 
AB6 2 3  N ALA B 585 ? N ALA B 585 O SER B 641 ? O SER B 641 
AB6 3 4  N VAL B 642 ? N VAL B 642 O THR B 673 ? O THR B 673 
AB7 1 2  O GLY B 595 ? O GLY B 595 N ASP B 591 ? N ASP B 591 
AB7 2 3  O GLY B 582 ? O GLY B 582 N GLN B 572 ? N GLN B 572 
AB7 3 4  N ILE B 573 ? N ILE B 573 O ILE B 781 ? O ILE B 781 
AB7 4 5  O VAL B 780 ? O VAL B 780 N VAL B 759 ? N VAL B 759 
AB7 5 6  O VAL B 760 ? O VAL B 760 N ILE B 725 ? N ILE B 725 
# 
_pdbx_entry_details.entry_id                   9BKV 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ARG A 164 ? ? 72.49   41.78   
2  1 GLN A 188 ? ? 78.33   130.41  
3  1 THR A 213 ? ? -97.64  36.10   
4  1 ALA A 244 ? ? 56.42   -159.95 
5  1 GLN A 385 ? ? 58.12   75.25   
6  1 PHE A 386 ? ? -106.64 60.98   
7  1 ASP A 387 ? ? 58.66   77.11   
8  1 SER A 428 ? ? -95.65  -60.14  
9  1 THR A 461 ? ? -105.39 42.71   
10 1 TYR A 507 ? ? -162.34 115.10  
11 1 LEU A 565 ? ? -67.63  -178.01 
12 1 SER A 600 ? ? -68.59  6.72    
13 1 HIS A 636 ? ? 61.70   -102.40 
14 1 GLU A 678 ? ? 72.89   -13.20  
15 1 HIS A 684 ? ? 47.32   -101.84 
16 1 ASP A 705 ? ? -134.94 -31.35  
17 1 ARG A 779 ? ? 79.47   -12.01  
18 1 TRP A 798 ? ? -130.47 -31.35  
19 1 LEU A 803 ? ? 67.69   176.98  
20 1 ASN B 64  ? ? 57.22   -123.85 
21 1 MET B 95  ? ? 58.05   12.64   
22 1 ALA B 200 ? ? -90.98  -61.79  
23 1 ASN B 202 ? ? -56.11  -9.17   
24 1 THR B 224 ? ? -77.78  -168.88 
25 1 ASP B 241 ? ? -74.56  -169.85 
26 1 ASN B 306 ? ? 56.13   14.97   
27 1 MET B 389 ? ? -97.43  -60.47  
28 1 LEU B 429 ? ? -141.94 13.56   
29 1 ASP B 452 ? ? 78.15   -13.99  
30 1 SER B 651 ? ? -90.72  -60.12  
31 1 ASP B 685 ? ? 79.67   175.70  
32 1 PHE B 707 ? ? 58.45   17.60   
33 1 GLU B 724 ? ? -171.40 134.21  
34 1 ARG B 734 ? ? 59.63   11.36   
35 1 ASN B 756 ? ? -94.52  54.04   
36 1 SER B 787 ? ? -160.11 115.17  
37 1 PRO B 791 ? ? -69.21  -175.82 
38 1 GLU B 794 ? ? 45.40   22.52   
39 1 LYS B 806 ? ? -69.44  76.68   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BKV 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BKV 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.43 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               391512 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Dimer of DosP' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BKV 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BKV 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BKV 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ARG 2   ? A ARG 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ASP 4   ? A ASP 4   
5  1 Y 1 A ALA 5   ? A ALA 5   
6  1 Y 1 A GLU 6   ? A GLU 6   
7  1 Y 1 A VAL 7   ? A VAL 7   
8  1 Y 1 A ILE 8   ? A ILE 8   
9  1 Y 1 A MET 9   ? A MET 9   
10 1 Y 1 A LYS 10  ? A LYS 10  
11 1 Y 1 A LEU 11  ? A LEU 11  
12 1 Y 1 A THR 12  ? A THR 12  
13 1 Y 1 A ASP 13  ? A ASP 13  
14 1 Y 1 A ALA 14  ? A ALA 14  
15 1 Y 1 A ASP 15  ? A ASP 15  
16 1 Y 1 A SER 16  ? A SER 16  
17 1 Y 1 A ALA 17  ? A ALA 17  
18 1 Y 1 A ALA 18  ? A ALA 18  
19 1 Y 1 A ASP 19  ? A ASP 19  
20 1 Y 1 B MET 1   ? B MET 1   
21 1 Y 1 B ARG 2   ? B ARG 2   
22 1 Y 1 B GLN 3   ? B GLN 3   
23 1 Y 1 B ASP 4   ? B ASP 4   
24 1 Y 1 B ALA 5   ? B ALA 5   
25 1 Y 1 B GLU 6   ? B GLU 6   
26 1 Y 1 B VAL 7   ? B VAL 7   
27 1 Y 1 B ILE 8   ? B ILE 8   
28 1 Y 1 B MET 9   ? B MET 9   
29 1 Y 1 B LYS 10  ? B LYS 10  
30 1 Y 1 B LEU 11  ? B LEU 11  
31 1 Y 1 B THR 12  ? B THR 12  
32 1 Y 1 B ASP 13  ? B ASP 13  
33 1 Y 1 B ALA 14  ? B ALA 14  
34 1 Y 1 B ASP 15  ? B ASP 15  
35 1 Y 1 B SER 16  ? B SER 16  
36 1 Y 1 B ALA 17  ? B ALA 17  
37 1 Y 1 B ALA 18  ? B ALA 18  
38 1 Y 1 B ASP 19  ? B ASP 19  
39 1 Y 1 B HIS 379 ? B HIS 379 
40 1 Y 1 B ILE 380 ? B ILE 380 
41 1 Y 1 B GLU 381 ? B GLU 381 
42 1 Y 1 B GLN 382 ? B GLN 382 
43 1 Y 1 B LEU 383 ? B LEU 383 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HEM CHA  C  N N 137 
HEM CHB  C  N N 138 
HEM CHC  C  N N 139 
HEM CHD  C  N N 140 
HEM C1A  C  Y N 141 
HEM C2A  C  Y N 142 
HEM C3A  C  Y N 143 
HEM C4A  C  Y N 144 
HEM CMA  C  N N 145 
HEM CAA  C  N N 146 
HEM CBA  C  N N 147 
HEM CGA  C  N N 148 
HEM O1A  O  N N 149 
HEM O2A  O  N N 150 
HEM C1B  C  N N 151 
HEM C2B  C  N N 152 
HEM C3B  C  N N 153 
HEM C4B  C  N N 154 
HEM CMB  C  N N 155 
HEM CAB  C  N N 156 
HEM CBB  C  N N 157 
HEM C1C  C  Y N 158 
HEM C2C  C  Y N 159 
HEM C3C  C  Y N 160 
HEM C4C  C  Y N 161 
HEM CMC  C  N N 162 
HEM CAC  C  N N 163 
HEM CBC  C  N N 164 
HEM C1D  C  N N 165 
HEM C2D  C  N N 166 
HEM C3D  C  N N 167 
HEM C4D  C  N N 168 
HEM CMD  C  N N 169 
HEM CAD  C  N N 170 
HEM CBD  C  N N 171 
HEM CGD  C  N N 172 
HEM O1D  O  N N 173 
HEM O2D  O  N N 174 
HEM NA   N  Y N 175 
HEM NB   N  N N 176 
HEM NC   N  Y N 177 
HEM ND   N  N N 178 
HEM FE   FE N N 179 
HEM HHB  H  N N 180 
HEM HHC  H  N N 181 
HEM HHD  H  N N 182 
HEM HMA  H  N N 183 
HEM HMAA H  N N 184 
HEM HMAB H  N N 185 
HEM HAA  H  N N 186 
HEM HAAA H  N N 187 
HEM HBA  H  N N 188 
HEM HBAA H  N N 189 
HEM HMB  H  N N 190 
HEM HMBA H  N N 191 
HEM HMBB H  N N 192 
HEM HAB  H  N N 193 
HEM HBB  H  N N 194 
HEM HBBA H  N N 195 
HEM HMC  H  N N 196 
HEM HMCA H  N N 197 
HEM HMCB H  N N 198 
HEM HAC  H  N N 199 
HEM HBC  H  N N 200 
HEM HBCA H  N N 201 
HEM HMD  H  N N 202 
HEM HMDA H  N N 203 
HEM HMDB H  N N 204 
HEM HAD  H  N N 205 
HEM HADA H  N N 206 
HEM HBD  H  N N 207 
HEM HBDA H  N N 208 
HEM H2A  H  N N 209 
HEM H2D  H  N N 210 
HEM HHA  H  N N 211 
HIS N    N  N N 212 
HIS CA   C  N S 213 
HIS C    C  N N 214 
HIS O    O  N N 215 
HIS CB   C  N N 216 
HIS CG   C  Y N 217 
HIS ND1  N  Y N 218 
HIS CD2  C  Y N 219 
HIS CE1  C  Y N 220 
HIS NE2  N  Y N 221 
HIS OXT  O  N N 222 
HIS H    H  N N 223 
HIS H2   H  N N 224 
HIS HA   H  N N 225 
HIS HB2  H  N N 226 
HIS HB3  H  N N 227 
HIS HD1  H  N N 228 
HIS HD2  H  N N 229 
HIS HE1  H  N N 230 
HIS HE2  H  N N 231 
HIS HXT  H  N N 232 
ILE N    N  N N 233 
ILE CA   C  N S 234 
ILE C    C  N N 235 
ILE O    O  N N 236 
ILE CB   C  N S 237 
ILE CG1  C  N N 238 
ILE CG2  C  N N 239 
ILE CD1  C  N N 240 
ILE OXT  O  N N 241 
ILE H    H  N N 242 
ILE H2   H  N N 243 
ILE HA   H  N N 244 
ILE HB   H  N N 245 
ILE HG12 H  N N 246 
ILE HG13 H  N N 247 
ILE HG21 H  N N 248 
ILE HG22 H  N N 249 
ILE HG23 H  N N 250 
ILE HD11 H  N N 251 
ILE HD12 H  N N 252 
ILE HD13 H  N N 253 
ILE HXT  H  N N 254 
LEU N    N  N N 255 
LEU CA   C  N S 256 
LEU C    C  N N 257 
LEU O    O  N N 258 
LEU CB   C  N N 259 
LEU CG   C  N N 260 
LEU CD1  C  N N 261 
LEU CD2  C  N N 262 
LEU OXT  O  N N 263 
LEU H    H  N N 264 
LEU H2   H  N N 265 
LEU HA   H  N N 266 
LEU HB2  H  N N 267 
LEU HB3  H  N N 268 
LEU HG   H  N N 269 
LEU HD11 H  N N 270 
LEU HD12 H  N N 271 
LEU HD13 H  N N 272 
LEU HD21 H  N N 273 
LEU HD22 H  N N 274 
LEU HD23 H  N N 275 
LEU HXT  H  N N 276 
LYS N    N  N N 277 
LYS CA   C  N S 278 
LYS C    C  N N 279 
LYS O    O  N N 280 
LYS CB   C  N N 281 
LYS CG   C  N N 282 
LYS CD   C  N N 283 
LYS CE   C  N N 284 
LYS NZ   N  N N 285 
LYS OXT  O  N N 286 
LYS H    H  N N 287 
LYS H2   H  N N 288 
LYS HA   H  N N 289 
LYS HB2  H  N N 290 
LYS HB3  H  N N 291 
LYS HG2  H  N N 292 
LYS HG3  H  N N 293 
LYS HD2  H  N N 294 
LYS HD3  H  N N 295 
LYS HE2  H  N N 296 
LYS HE3  H  N N 297 
LYS HZ1  H  N N 298 
LYS HZ2  H  N N 299 
LYS HZ3  H  N N 300 
LYS HXT  H  N N 301 
MET N    N  N N 302 
MET CA   C  N S 303 
MET C    C  N N 304 
MET O    O  N N 305 
MET CB   C  N N 306 
MET CG   C  N N 307 
MET SD   S  N N 308 
MET CE   C  N N 309 
MET OXT  O  N N 310 
MET H    H  N N 311 
MET H2   H  N N 312 
MET HA   H  N N 313 
MET HB2  H  N N 314 
MET HB3  H  N N 315 
MET HG2  H  N N 316 
MET HG3  H  N N 317 
MET HE1  H  N N 318 
MET HE2  H  N N 319 
MET HE3  H  N N 320 
MET HXT  H  N N 321 
PHE N    N  N N 322 
PHE CA   C  N S 323 
PHE C    C  N N 324 
PHE O    O  N N 325 
PHE CB   C  N N 326 
PHE CG   C  Y N 327 
PHE CD1  C  Y N 328 
PHE CD2  C  Y N 329 
PHE CE1  C  Y N 330 
PHE CE2  C  Y N 331 
PHE CZ   C  Y N 332 
PHE OXT  O  N N 333 
PHE H    H  N N 334 
PHE H2   H  N N 335 
PHE HA   H  N N 336 
PHE HB2  H  N N 337 
PHE HB3  H  N N 338 
PHE HD1  H  N N 339 
PHE HD2  H  N N 340 
PHE HE1  H  N N 341 
PHE HE2  H  N N 342 
PHE HZ   H  N N 343 
PHE HXT  H  N N 344 
PRO N    N  N N 345 
PRO CA   C  N S 346 
PRO C    C  N N 347 
PRO O    O  N N 348 
PRO CB   C  N N 349 
PRO CG   C  N N 350 
PRO CD   C  N N 351 
PRO OXT  O  N N 352 
PRO H    H  N N 353 
PRO HA   H  N N 354 
PRO HB2  H  N N 355 
PRO HB3  H  N N 356 
PRO HG2  H  N N 357 
PRO HG3  H  N N 358 
PRO HD2  H  N N 359 
PRO HD3  H  N N 360 
PRO HXT  H  N N 361 
SER N    N  N N 362 
SER CA   C  N S 363 
SER C    C  N N 364 
SER O    O  N N 365 
SER CB   C  N N 366 
SER OG   O  N N 367 
SER OXT  O  N N 368 
SER H    H  N N 369 
SER H2   H  N N 370 
SER HA   H  N N 371 
SER HB2  H  N N 372 
SER HB3  H  N N 373 
SER HG   H  N N 374 
SER HXT  H  N N 375 
THR N    N  N N 376 
THR CA   C  N S 377 
THR C    C  N N 378 
THR O    O  N N 379 
THR CB   C  N R 380 
THR OG1  O  N N 381 
THR CG2  C  N N 382 
THR OXT  O  N N 383 
THR H    H  N N 384 
THR H2   H  N N 385 
THR HA   H  N N 386 
THR HB   H  N N 387 
THR HG1  H  N N 388 
THR HG21 H  N N 389 
THR HG22 H  N N 390 
THR HG23 H  N N 391 
THR HXT  H  N N 392 
TRP N    N  N N 393 
TRP CA   C  N S 394 
TRP C    C  N N 395 
TRP O    O  N N 396 
TRP CB   C  N N 397 
TRP CG   C  Y N 398 
TRP CD1  C  Y N 399 
TRP CD2  C  Y N 400 
TRP NE1  N  Y N 401 
TRP CE2  C  Y N 402 
TRP CE3  C  Y N 403 
TRP CZ2  C  Y N 404 
TRP CZ3  C  Y N 405 
TRP CH2  C  Y N 406 
TRP OXT  O  N N 407 
TRP H    H  N N 408 
TRP H2   H  N N 409 
TRP HA   H  N N 410 
TRP HB2  H  N N 411 
TRP HB3  H  N N 412 
TRP HD1  H  N N 413 
TRP HE1  H  N N 414 
TRP HE3  H  N N 415 
TRP HZ2  H  N N 416 
TRP HZ3  H  N N 417 
TRP HH2  H  N N 418 
TRP HXT  H  N N 419 
TYR N    N  N N 420 
TYR CA   C  N S 421 
TYR C    C  N N 422 
TYR O    O  N N 423 
TYR CB   C  N N 424 
TYR CG   C  Y N 425 
TYR CD1  C  Y N 426 
TYR CD2  C  Y N 427 
TYR CE1  C  Y N 428 
TYR CE2  C  Y N 429 
TYR CZ   C  Y N 430 
TYR OH   O  N N 431 
TYR OXT  O  N N 432 
TYR H    H  N N 433 
TYR H2   H  N N 434 
TYR HA   H  N N 435 
TYR HB2  H  N N 436 
TYR HB3  H  N N 437 
TYR HD1  H  N N 438 
TYR HD2  H  N N 439 
TYR HE1  H  N N 440 
TYR HE2  H  N N 441 
TYR HH   H  N N 442 
TYR HXT  H  N N 443 
VAL N    N  N N 444 
VAL CA   C  N S 445 
VAL C    C  N N 446 
VAL O    O  N N 447 
VAL CB   C  N N 448 
VAL CG1  C  N N 449 
VAL CG2  C  N N 450 
VAL OXT  O  N N 451 
VAL H    H  N N 452 
VAL H2   H  N N 453 
VAL HA   H  N N 454 
VAL HB   H  N N 455 
VAL HG11 H  N N 456 
VAL HG12 H  N N 457 
VAL HG13 H  N N 458 
VAL HG21 H  N N 459 
VAL HG22 H  N N 460 
VAL HG23 H  N N 461 
VAL HXT  H  N N 462 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEM CHA C1A  sing N N 129 
HEM CHA C4D  doub N N 130 
HEM CHA HHA  sing N N 131 
HEM CHB C4A  sing N N 132 
HEM CHB C1B  doub N N 133 
HEM CHB HHB  sing N N 134 
HEM CHC C4B  sing N N 135 
HEM CHC C1C  doub N N 136 
HEM CHC HHC  sing N N 137 
HEM CHD C4C  doub N N 138 
HEM CHD C1D  sing N N 139 
HEM CHD HHD  sing N N 140 
HEM C1A C2A  doub Y N 141 
HEM C1A NA   sing Y N 142 
HEM C2A C3A  sing Y N 143 
HEM C2A CAA  sing N N 144 
HEM C3A C4A  doub Y N 145 
HEM C3A CMA  sing N N 146 
HEM C4A NA   sing Y N 147 
HEM CMA HMA  sing N N 148 
HEM CMA HMAA sing N N 149 
HEM CMA HMAB sing N N 150 
HEM CAA CBA  sing N N 151 
HEM CAA HAA  sing N N 152 
HEM CAA HAAA sing N N 153 
HEM CBA CGA  sing N N 154 
HEM CBA HBA  sing N N 155 
HEM CBA HBAA sing N N 156 
HEM CGA O1A  doub N N 157 
HEM CGA O2A  sing N N 158 
HEM C1B C2B  sing N N 159 
HEM C1B NB   sing N N 160 
HEM C2B C3B  doub N N 161 
HEM C2B CMB  sing N N 162 
HEM C3B C4B  sing N N 163 
HEM C3B CAB  sing N N 164 
HEM C4B NB   doub N N 165 
HEM CMB HMB  sing N N 166 
HEM CMB HMBA sing N N 167 
HEM CMB HMBB sing N N 168 
HEM CAB CBB  doub N N 169 
HEM CAB HAB  sing N N 170 
HEM CBB HBB  sing N N 171 
HEM CBB HBBA sing N N 172 
HEM C1C C2C  sing Y N 173 
HEM C1C NC   sing Y N 174 
HEM C2C C3C  doub Y N 175 
HEM C2C CMC  sing N N 176 
HEM C3C C4C  sing Y N 177 
HEM C3C CAC  sing N N 178 
HEM C4C NC   sing Y N 179 
HEM CMC HMC  sing N N 180 
HEM CMC HMCA sing N N 181 
HEM CMC HMCB sing N N 182 
HEM CAC CBC  doub N N 183 
HEM CAC HAC  sing N N 184 
HEM CBC HBC  sing N N 185 
HEM CBC HBCA sing N N 186 
HEM C1D C2D  sing N N 187 
HEM C1D ND   doub N N 188 
HEM C2D C3D  doub N N 189 
HEM C2D CMD  sing N N 190 
HEM C3D C4D  sing N N 191 
HEM C3D CAD  sing N N 192 
HEM C4D ND   sing N N 193 
HEM CMD HMD  sing N N 194 
HEM CMD HMDA sing N N 195 
HEM CMD HMDB sing N N 196 
HEM CAD CBD  sing N N 197 
HEM CAD HAD  sing N N 198 
HEM CAD HADA sing N N 199 
HEM CBD CGD  sing N N 200 
HEM CBD HBD  sing N N 201 
HEM CBD HBDA sing N N 202 
HEM CGD O1D  doub N N 203 
HEM CGD O2D  sing N N 204 
HEM O2A H2A  sing N N 205 
HEM O2D H2D  sing N N 206 
HEM FE  NA   sing N N 207 
HEM FE  NB   sing N N 208 
HEM FE  NC   sing N N 209 
HEM FE  ND   sing N N 210 
HIS N   CA   sing N N 211 
HIS N   H    sing N N 212 
HIS N   H2   sing N N 213 
HIS CA  C    sing N N 214 
HIS CA  CB   sing N N 215 
HIS CA  HA   sing N N 216 
HIS C   O    doub N N 217 
HIS C   OXT  sing N N 218 
HIS CB  CG   sing N N 219 
HIS CB  HB2  sing N N 220 
HIS CB  HB3  sing N N 221 
HIS CG  ND1  sing Y N 222 
HIS CG  CD2  doub Y N 223 
HIS ND1 CE1  doub Y N 224 
HIS ND1 HD1  sing N N 225 
HIS CD2 NE2  sing Y N 226 
HIS CD2 HD2  sing N N 227 
HIS CE1 NE2  sing Y N 228 
HIS CE1 HE1  sing N N 229 
HIS NE2 HE2  sing N N 230 
HIS OXT HXT  sing N N 231 
ILE N   CA   sing N N 232 
ILE N   H    sing N N 233 
ILE N   H2   sing N N 234 
ILE CA  C    sing N N 235 
ILE CA  CB   sing N N 236 
ILE CA  HA   sing N N 237 
ILE C   O    doub N N 238 
ILE C   OXT  sing N N 239 
ILE CB  CG1  sing N N 240 
ILE CB  CG2  sing N N 241 
ILE CB  HB   sing N N 242 
ILE CG1 CD1  sing N N 243 
ILE CG1 HG12 sing N N 244 
ILE CG1 HG13 sing N N 245 
ILE CG2 HG21 sing N N 246 
ILE CG2 HG22 sing N N 247 
ILE CG2 HG23 sing N N 248 
ILE CD1 HD11 sing N N 249 
ILE CD1 HD12 sing N N 250 
ILE CD1 HD13 sing N N 251 
ILE OXT HXT  sing N N 252 
LEU N   CA   sing N N 253 
LEU N   H    sing N N 254 
LEU N   H2   sing N N 255 
LEU CA  C    sing N N 256 
LEU CA  CB   sing N N 257 
LEU CA  HA   sing N N 258 
LEU C   O    doub N N 259 
LEU C   OXT  sing N N 260 
LEU CB  CG   sing N N 261 
LEU CB  HB2  sing N N 262 
LEU CB  HB3  sing N N 263 
LEU CG  CD1  sing N N 264 
LEU CG  CD2  sing N N 265 
LEU CG  HG   sing N N 266 
LEU CD1 HD11 sing N N 267 
LEU CD1 HD12 sing N N 268 
LEU CD1 HD13 sing N N 269 
LEU CD2 HD21 sing N N 270 
LEU CD2 HD22 sing N N 271 
LEU CD2 HD23 sing N N 272 
LEU OXT HXT  sing N N 273 
LYS N   CA   sing N N 274 
LYS N   H    sing N N 275 
LYS N   H2   sing N N 276 
LYS CA  C    sing N N 277 
LYS CA  CB   sing N N 278 
LYS CA  HA   sing N N 279 
LYS C   O    doub N N 280 
LYS C   OXT  sing N N 281 
LYS CB  CG   sing N N 282 
LYS CB  HB2  sing N N 283 
LYS CB  HB3  sing N N 284 
LYS CG  CD   sing N N 285 
LYS CG  HG2  sing N N 286 
LYS CG  HG3  sing N N 287 
LYS CD  CE   sing N N 288 
LYS CD  HD2  sing N N 289 
LYS CD  HD3  sing N N 290 
LYS CE  NZ   sing N N 291 
LYS CE  HE2  sing N N 292 
LYS CE  HE3  sing N N 293 
LYS NZ  HZ1  sing N N 294 
LYS NZ  HZ2  sing N N 295 
LYS NZ  HZ3  sing N N 296 
LYS OXT HXT  sing N N 297 
MET N   CA   sing N N 298 
MET N   H    sing N N 299 
MET N   H2   sing N N 300 
MET CA  C    sing N N 301 
MET CA  CB   sing N N 302 
MET CA  HA   sing N N 303 
MET C   O    doub N N 304 
MET C   OXT  sing N N 305 
MET CB  CG   sing N N 306 
MET CB  HB2  sing N N 307 
MET CB  HB3  sing N N 308 
MET CG  SD   sing N N 309 
MET CG  HG2  sing N N 310 
MET CG  HG3  sing N N 311 
MET SD  CE   sing N N 312 
MET CE  HE1  sing N N 313 
MET CE  HE2  sing N N 314 
MET CE  HE3  sing N N 315 
MET OXT HXT  sing N N 316 
PHE N   CA   sing N N 317 
PHE N   H    sing N N 318 
PHE N   H2   sing N N 319 
PHE CA  C    sing N N 320 
PHE CA  CB   sing N N 321 
PHE CA  HA   sing N N 322 
PHE C   O    doub N N 323 
PHE C   OXT  sing N N 324 
PHE CB  CG   sing N N 325 
PHE CB  HB2  sing N N 326 
PHE CB  HB3  sing N N 327 
PHE CG  CD1  doub Y N 328 
PHE CG  CD2  sing Y N 329 
PHE CD1 CE1  sing Y N 330 
PHE CD1 HD1  sing N N 331 
PHE CD2 CE2  doub Y N 332 
PHE CD2 HD2  sing N N 333 
PHE CE1 CZ   doub Y N 334 
PHE CE1 HE1  sing N N 335 
PHE CE2 CZ   sing Y N 336 
PHE CE2 HE2  sing N N 337 
PHE CZ  HZ   sing N N 338 
PHE OXT HXT  sing N N 339 
PRO N   CA   sing N N 340 
PRO N   CD   sing N N 341 
PRO N   H    sing N N 342 
PRO CA  C    sing N N 343 
PRO CA  CB   sing N N 344 
PRO CA  HA   sing N N 345 
PRO C   O    doub N N 346 
PRO C   OXT  sing N N 347 
PRO CB  CG   sing N N 348 
PRO CB  HB2  sing N N 349 
PRO CB  HB3  sing N N 350 
PRO CG  CD   sing N N 351 
PRO CG  HG2  sing N N 352 
PRO CG  HG3  sing N N 353 
PRO CD  HD2  sing N N 354 
PRO CD  HD3  sing N N 355 
PRO OXT HXT  sing N N 356 
SER N   CA   sing N N 357 
SER N   H    sing N N 358 
SER N   H2   sing N N 359 
SER CA  C    sing N N 360 
SER CA  CB   sing N N 361 
SER CA  HA   sing N N 362 
SER C   O    doub N N 363 
SER C   OXT  sing N N 364 
SER CB  OG   sing N N 365 
SER CB  HB2  sing N N 366 
SER CB  HB3  sing N N 367 
SER OG  HG   sing N N 368 
SER OXT HXT  sing N N 369 
THR N   CA   sing N N 370 
THR N   H    sing N N 371 
THR N   H2   sing N N 372 
THR CA  C    sing N N 373 
THR CA  CB   sing N N 374 
THR CA  HA   sing N N 375 
THR C   O    doub N N 376 
THR C   OXT  sing N N 377 
THR CB  OG1  sing N N 378 
THR CB  CG2  sing N N 379 
THR CB  HB   sing N N 380 
THR OG1 HG1  sing N N 381 
THR CG2 HG21 sing N N 382 
THR CG2 HG22 sing N N 383 
THR CG2 HG23 sing N N 384 
THR OXT HXT  sing N N 385 
TRP N   CA   sing N N 386 
TRP N   H    sing N N 387 
TRP N   H2   sing N N 388 
TRP CA  C    sing N N 389 
TRP CA  CB   sing N N 390 
TRP CA  HA   sing N N 391 
TRP C   O    doub N N 392 
TRP C   OXT  sing N N 393 
TRP CB  CG   sing N N 394 
TRP CB  HB2  sing N N 395 
TRP CB  HB3  sing N N 396 
TRP CG  CD1  doub Y N 397 
TRP CG  CD2  sing Y N 398 
TRP CD1 NE1  sing Y N 399 
TRP CD1 HD1  sing N N 400 
TRP CD2 CE2  doub Y N 401 
TRP CD2 CE3  sing Y N 402 
TRP NE1 CE2  sing Y N 403 
TRP NE1 HE1  sing N N 404 
TRP CE2 CZ2  sing Y N 405 
TRP CE3 CZ3  doub Y N 406 
TRP CE3 HE3  sing N N 407 
TRP CZ2 CH2  doub Y N 408 
TRP CZ2 HZ2  sing N N 409 
TRP CZ3 CH2  sing Y N 410 
TRP CZ3 HZ3  sing N N 411 
TRP CH2 HH2  sing N N 412 
TRP OXT HXT  sing N N 413 
TYR N   CA   sing N N 414 
TYR N   H    sing N N 415 
TYR N   H2   sing N N 416 
TYR CA  C    sing N N 417 
TYR CA  CB   sing N N 418 
TYR CA  HA   sing N N 419 
TYR C   O    doub N N 420 
TYR C   OXT  sing N N 421 
TYR CB  CG   sing N N 422 
TYR CB  HB2  sing N N 423 
TYR CB  HB3  sing N N 424 
TYR CG  CD1  doub Y N 425 
TYR CG  CD2  sing Y N 426 
TYR CD1 CE1  sing Y N 427 
TYR CD1 HD1  sing N N 428 
TYR CD2 CE2  doub Y N 429 
TYR CD2 HD2  sing N N 430 
TYR CE1 CZ   doub Y N 431 
TYR CE1 HE1  sing N N 432 
TYR CE2 CZ   sing Y N 433 
TYR CE2 HE2  sing N N 434 
TYR CZ  OH   sing N N 435 
TYR OH  HH   sing N N 436 
TYR OXT HXT  sing N N 437 
VAL N   CA   sing N N 438 
VAL N   H    sing N N 439 
VAL N   H2   sing N N 440 
VAL CA  C    sing N N 441 
VAL CA  CB   sing N N 442 
VAL CA  HA   sing N N 443 
VAL C   O    doub N N 444 
VAL C   OXT  sing N N 445 
VAL CB  CG1  sing N N 446 
VAL CB  CG2  sing N N 447 
VAL CB  HB   sing N N 448 
VAL CG1 HG11 sing N N 449 
VAL CG1 HG12 sing N N 450 
VAL CG1 HG13 sing N N 451 
VAL CG2 HG21 sing N N 452 
VAL CG2 HG22 sing N N 453 
VAL CG2 HG23 sing N N 454 
VAL OXT HXT  sing N N 455 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-29 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BKV 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'DosP R97A bent form' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.2 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?         ?   
MASKING                    ? 3  ? ? ? ?         ?   
'CTF CORRECTION'           ? 4  1 ? ? ?         ?   
'LAYERLINE INDEXING'       ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?         ?   
'MODEL FITTING'            ? 7  ? ? ? ?         ?   
'MODEL REFINEMENT'         ? 8  ? ? ? ?         ?   
OTHER                      ? 9  ? ? ? ?         ?   
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? cryoSPARC 4.2 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? cryoSPARC 4.2 
CLASSIFICATION             ? 12 1 ? ? ?         ?   
RECONSTRUCTION             ? 13 1 ? ? ?         ?   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' GM141261 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' GM129547 2 
# 
_atom_sites.entry_id                    9BKV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . GLY A 1 20  ? 178.709 224.440 302.495 1.00 154.50 ? 20  GLY A N   1 
ATOM   2     C  CA  . GLY A 1 20  ? 180.125 224.515 302.805 1.00 154.12 ? 20  GLY A CA  1 
ATOM   3     C  C   . GLY A 1 20  ? 180.909 225.359 301.820 1.00 158.80 ? 20  GLY A C   1 
ATOM   4     O  O   . GLY A 1 20  ? 180.373 225.800 300.804 1.00 158.39 ? 20  GLY A O   1 
ATOM   5     N  N   . ILE A 1 21  ? 182.189 225.587 302.127 1.00 159.62 ? 21  ILE A N   1 
ATOM   6     C  CA  . ILE A 1 21  ? 183.037 226.384 301.249 1.00 157.16 ? 21  ILE A CA  1 
ATOM   7     C  C   . ILE A 1 21  ? 183.427 225.621 299.990 1.00 152.01 ? 21  ILE A C   1 
ATOM   8     O  O   . ILE A 1 21  ? 183.865 226.233 299.007 1.00 148.13 ? 21  ILE A O   1 
ATOM   9     C  CB  . ILE A 1 21  ? 184.295 226.854 302.002 1.00 155.46 ? 21  ILE A CB  1 
ATOM   10    C  CG1 . ILE A 1 21  ? 185.217 225.667 302.292 1.00 153.06 ? 21  ILE A CG1 1 
ATOM   11    C  CG2 . ILE A 1 21  ? 183.910 227.559 303.291 1.00 153.07 ? 21  ILE A CG2 1 
ATOM   12    C  CD1 . ILE A 1 21  ? 186.467 226.035 303.060 1.00 148.66 ? 21  ILE A CD1 1 
ATOM   13    N  N   . PHE A 1 22  ? 183.279 224.296 299.989 1.00 153.82 ? 22  PHE A N   1 
ATOM   14    C  CA  . PHE A 1 22  ? 183.688 223.514 298.830 1.00 150.05 ? 22  PHE A CA  1 
ATOM   15    C  C   . PHE A 1 22  ? 182.743 223.680 297.650 1.00 143.64 ? 22  PHE A C   1 
ATOM   16    O  O   . PHE A 1 22  ? 183.169 223.496 296.508 1.00 135.31 ? 22  PHE A O   1 
ATOM   17    C  CB  . PHE A 1 22  ? 183.816 222.042 299.210 1.00 147.66 ? 22  PHE A CB  1 
ATOM   18    C  CG  . PHE A 1 22  ? 185.070 221.732 299.971 1.00 149.02 ? 22  PHE A CG  1 
ATOM   19    C  CD1 . PHE A 1 22  ? 185.152 221.986 301.329 1.00 150.48 ? 22  PHE A CD1 1 
ATOM   20    C  CD2 . PHE A 1 22  ? 186.174 221.206 299.323 1.00 146.94 ? 22  PHE A CD2 1 
ATOM   21    C  CE1 . PHE A 1 22  ? 186.309 221.711 302.027 1.00 149.47 ? 22  PHE A CE1 1 
ATOM   22    C  CE2 . PHE A 1 22  ? 187.334 220.929 300.017 1.00 146.82 ? 22  PHE A CE2 1 
ATOM   23    C  CZ  . PHE A 1 22  ? 187.402 221.181 301.369 1.00 148.43 ? 22  PHE A CZ  1 
ATOM   24    N  N   . PHE A 1 23  ? 181.482 224.028 297.893 1.00 144.54 ? 23  PHE A N   1 
ATOM   25    C  CA  . PHE A 1 23  ? 180.603 224.366 296.776 1.00 142.45 ? 23  PHE A CA  1 
ATOM   26    C  C   . PHE A 1 23  ? 181.132 225.572 296.009 1.00 140.17 ? 23  PHE A C   1 
ATOM   27    O  O   . PHE A 1 23  ? 181.342 225.452 294.790 1.00 138.21 ? 23  PHE A O   1 
ATOM   28    C  CB  . PHE A 1 23  ? 179.172 224.570 297.296 1.00 144.74 ? 23  PHE A CB  1 
ATOM   29    C  CG  . PHE A 1 23  ? 178.125 224.648 296.217 1.00 148.74 ? 23  PHE A CG  1 
ATOM   30    C  CD1 . PHE A 1 23  ? 177.952 225.805 295.473 1.00 148.55 ? 23  PHE A CD1 1 
ATOM   31    C  CD2 . PHE A 1 23  ? 177.281 223.575 295.979 1.00 148.00 ? 23  PHE A CD2 1 
ATOM   32    C  CE1 . PHE A 1 23  ? 176.982 225.878 294.490 1.00 147.18 ? 23  PHE A CE1 1 
ATOM   33    C  CE2 . PHE A 1 23  ? 176.305 223.644 295.000 1.00 147.79 ? 23  PHE A CE2 1 
ATOM   34    C  CZ  . PHE A 1 23  ? 176.157 224.796 294.255 1.00 147.71 ? 23  PHE A CZ  1 
ATOM   35    N  N   . PRO A 1 24  ? 181.409 226.725 296.633 1.00 140.47 ? 24  PRO A N   1 
ATOM   36    C  CA  . PRO A 1 24  ? 182.081 227.797 295.882 1.00 138.35 ? 24  PRO A CA  1 
ATOM   37    C  C   . PRO A 1 24  ? 183.454 227.405 295.378 1.00 134.64 ? 24  PRO A C   1 
ATOM   38    O  O   . PRO A 1 24  ? 183.865 227.872 294.308 1.00 133.01 ? 24  PRO A O   1 
ATOM   39    C  CB  . PRO A 1 24  ? 182.162 228.944 296.900 1.00 140.06 ? 24  PRO A CB  1 
ATOM   40    C  CG  . PRO A 1 24  ? 181.089 228.661 297.877 1.00 140.20 ? 24  PRO A CG  1 
ATOM   41    C  CD  . PRO A 1 24  ? 181.057 227.172 297.993 1.00 142.51 ? 24  PRO A CD  1 
ATOM   42    N  N   . ALA A 1 25  ? 184.186 226.570 296.120 1.00 134.06 ? 25  ALA A N   1 
ATOM   43    C  CA  . ALA A 1 25  ? 185.490 226.125 295.646 1.00 128.93 ? 25  ALA A CA  1 
ATOM   44    C  C   . ALA A 1 25  ? 185.362 225.475 294.283 1.00 125.92 ? 25  ALA A C   1 
ATOM   45    O  O   . ALA A 1 25  ? 185.852 226.005 293.281 1.00 123.58 ? 25  ALA A O   1 
ATOM   46    C  CB  . ALA A 1 25  ? 186.112 225.155 296.646 1.00 133.22 ? 25  ALA A CB  1 
ATOM   47    N  N   . LEU A 1 26  ? 184.634 224.361 294.222 1.00 129.98 ? 26  LEU A N   1 
ATOM   48    C  CA  . LEU A 1 26  ? 184.389 223.675 292.961 1.00 137.94 ? 26  LEU A CA  1 
ATOM   49    C  C   . LEU A 1 26  ? 183.721 224.591 291.943 1.00 138.29 ? 26  LEU A C   1 
ATOM   50    O  O   . LEU A 1 26  ? 183.853 224.371 290.733 1.00 137.44 ? 26  LEU A O   1 
ATOM   51    C  CB  . LEU A 1 26  ? 183.530 222.437 293.212 1.00 138.97 ? 26  LEU A CB  1 
ATOM   52    C  CG  . LEU A 1 26  ? 184.126 221.347 294.102 1.00 137.58 ? 26  LEU A CG  1 
ATOM   53    C  CD1 . LEU A 1 26  ? 183.033 220.410 294.592 1.00 138.15 ? 26  LEU A CD1 1 
ATOM   54    C  CD2 . LEU A 1 26  ? 185.198 220.570 293.358 1.00 136.62 ? 26  LEU A CD2 1 
ATOM   55    N  N   . GLU A 1 27  ? 183.000 225.617 292.405 1.00 136.78 ? 27  GLU A N   1 
ATOM   56    C  CA  . GLU A 1 27  ? 182.489 226.621 291.479 1.00 137.70 ? 27  GLU A CA  1 
ATOM   57    C  C   . GLU A 1 27  ? 183.620 227.443 290.875 1.00 136.80 ? 27  GLU A C   1 
ATOM   58    O  O   . GLU A 1 27  ? 183.471 228.003 289.783 1.00 139.24 ? 27  GLU A O   1 
ATOM   59    C  CB  . GLU A 1 27  ? 181.491 227.535 292.187 1.00 139.41 ? 27  GLU A CB  1 
ATOM   60    C  CG  . GLU A 1 27  ? 180.054 227.044 292.146 1.00 143.16 ? 27  GLU A CG  1 
ATOM   61    C  CD  . GLU A 1 27  ? 179.052 228.156 292.390 1.00 148.82 ? 27  GLU A CD  1 
ATOM   62    O  OE1 . GLU A 1 27  ? 179.310 229.011 293.264 1.00 145.92 ? 27  GLU A OE1 1 
ATOM   63    O  OE2 . GLU A 1 27  ? 178.007 228.178 291.706 1.00 153.61 ? 27  GLU A OE2 1 
ATOM   64    N  N   . GLN A 1 28  ? 184.753 227.531 291.566 1.00 132.05 ? 28  GLN A N   1 
ATOM   65    C  CA  . GLN A 1 28  ? 185.827 228.419 291.149 1.00 129.22 ? 28  GLN A CA  1 
ATOM   66    C  C   . GLN A 1 28  ? 187.067 227.700 290.634 1.00 123.12 ? 28  GLN A C   1 
ATOM   67    O  O   . GLN A 1 28  ? 187.972 228.365 290.125 1.00 122.34 ? 28  GLN A O   1 
ATOM   68    C  CB  . GLN A 1 28  ? 186.212 229.346 292.304 1.00 133.11 ? 28  GLN A CB  1 
ATOM   69    C  CG  . GLN A 1 28  ? 185.254 230.513 292.489 1.00 134.53 ? 28  GLN A CG  1 
ATOM   70    C  CD  . GLN A 1 28  ? 185.482 231.261 293.785 1.00 140.44 ? 28  GLN A CD  1 
ATOM   71    O  OE1 . GLN A 1 28  ? 184.628 231.265 294.672 1.00 140.90 ? 28  GLN A OE1 1 
ATOM   72    N  NE2 . GLN A 1 28  ? 186.639 231.902 293.903 1.00 142.16 ? 28  GLN A NE2 1 
ATOM   73    N  N   . ASN A 1 29  ? 187.143 226.376 290.736 1.00 120.57 ? 29  ASN A N   1 
ATOM   74    C  CA  . ASN A 1 29  ? 188.288 225.689 290.157 1.00 119.23 ? 29  ASN A CA  1 
ATOM   75    C  C   . ASN A 1 29  ? 188.299 225.828 288.644 1.00 116.08 ? 29  ASN A C   1 
ATOM   76    O  O   . ASN A 1 29  ? 187.258 225.977 288.001 1.00 117.37 ? 29  ASN A O   1 
ATOM   77    C  CB  . ASN A 1 29  ? 188.303 224.199 290.503 1.00 126.19 ? 29  ASN A CB  1 
ATOM   78    C  CG  . ASN A 1 29  ? 187.888 223.912 291.920 1.00 131.03 ? 29  ASN A CG  1 
ATOM   79    O  OD1 . ASN A 1 29  ? 187.945 224.781 292.776 1.00 128.42 ? 29  ASN A OD1 1 
ATOM   80    N  ND2 . ASN A 1 29  ? 187.474 222.678 292.177 1.00 135.00 ? 29  ASN A ND2 1 
ATOM   81    N  N   . MET A 1 30  ? 189.503 225.785 288.078 1.00 113.54 ? 30  MET A N   1 
ATOM   82    C  CA  . MET A 1 30  ? 189.625 225.548 286.649 1.00 116.97 ? 30  MET A CA  1 
ATOM   83    C  C   . MET A 1 30  ? 189.104 224.165 286.294 1.00 123.77 ? 30  MET A C   1 
ATOM   84    O  O   . MET A 1 30  ? 188.666 223.943 285.160 1.00 126.35 ? 30  MET A O   1 
ATOM   85    C  CB  . MET A 1 30  ? 191.086 225.741 286.223 1.00 115.34 ? 30  MET A CB  1 
ATOM   86    C  CG  . MET A 1 30  ? 191.506 225.093 284.908 1.00 119.50 ? 30  MET A CG  1 
ATOM   87    S  SD  . MET A 1 30  ? 192.012 223.370 285.036 1.00 126.68 ? 30  MET A SD  1 
ATOM   88    C  CE  . MET A 1 30  ? 193.777 223.565 285.258 1.00 122.53 ? 30  MET A CE  1 
ATOM   89    N  N   . MET A 1 31  ? 189.112 223.250 287.257 1.00 126.32 ? 31  MET A N   1 
ATOM   90    C  CA  . MET A 1 31  ? 188.595 221.903 287.076 1.00 128.02 ? 31  MET A CA  1 
ATOM   91    C  C   . MET A 1 31  ? 187.089 221.934 286.821 1.00 130.37 ? 31  MET A C   1 
ATOM   92    O  O   . MET A 1 31  ? 186.366 222.780 287.352 1.00 132.94 ? 31  MET A O   1 
ATOM   93    C  CB  . MET A 1 31  ? 188.904 221.072 288.324 1.00 127.83 ? 31  MET A CB  1 
ATOM   94    C  CG  . MET A 1 31  ? 188.459 219.616 288.316 1.00 125.84 ? 31  MET A CG  1 
ATOM   95    S  SD  . MET A 1 31  ? 188.200 218.846 286.709 1.00 127.29 ? 31  MET A SD  1 
ATOM   96    C  CE  . MET A 1 31  ? 189.831 218.968 285.969 1.00 111.91 ? 31  MET A CE  1 
ATOM   97    N  N   . GLY A 1 32  ? 186.612 220.999 285.996 1.00 127.74 ? 32  GLY A N   1 
ATOM   98    C  CA  . GLY A 1 32  ? 185.184 220.911 285.733 1.00 126.32 ? 32  GLY A CA  1 
ATOM   99    C  C   . GLY A 1 32  ? 184.429 220.094 286.764 1.00 125.32 ? 32  GLY A C   1 
ATOM   100   O  O   . GLY A 1 32  ? 184.617 218.882 286.842 1.00 116.54 ? 32  GLY A O   1 
ATOM   101   N  N   . ALA A 1 33  ? 183.568 220.726 287.553 1.00 133.28 ? 33  ALA A N   1 
ATOM   102   C  CA  . ALA A 1 33  ? 182.933 220.062 288.684 1.00 135.34 ? 33  ALA A CA  1 
ATOM   103   C  C   . ALA A 1 33  ? 181.465 219.773 288.398 1.00 135.71 ? 33  ALA A C   1 
ATOM   104   O  O   . ALA A 1 33  ? 180.706 220.677 288.035 1.00 136.49 ? 33  ALA A O   1 
ATOM   105   C  CB  . ALA A 1 33  ? 183.066 220.910 289.949 1.00 136.57 ? 33  ALA A CB  1 
ATOM   106   N  N   . VAL A 1 34  ? 181.070 218.512 288.576 1.00 133.36 ? 34  VAL A N   1 
ATOM   107   C  CA  . VAL A 1 34  ? 179.688 218.081 288.427 1.00 133.55 ? 34  VAL A CA  1 
ATOM   108   C  C   . VAL A 1 34  ? 179.397 217.072 289.526 1.00 128.88 ? 34  VAL A C   1 
ATOM   109   O  O   . VAL A 1 34  ? 180.248 216.256 289.881 1.00 122.67 ? 34  VAL A O   1 
ATOM   110   C  CB  . VAL A 1 34  ? 179.427 217.466 287.030 1.00 135.24 ? 34  VAL A CB  1 
ATOM   111   C  CG1 . VAL A 1 34  ? 178.089 216.747 286.990 1.00 137.42 ? 34  VAL A CG1 1 
ATOM   112   C  CG2 . VAL A 1 34  ? 179.485 218.536 285.948 1.00 137.76 ? 34  VAL A CG2 1 
ATOM   113   N  N   . LEU A 1 35  ? 178.197 217.141 290.091 1.00 133.33 ? 35  LEU A N   1 
ATOM   114   C  CA  . LEU A 1 35  ? 177.785 216.153 291.073 1.00 135.17 ? 35  LEU A CA  1 
ATOM   115   C  C   . LEU A 1 35  ? 176.362 215.718 290.766 1.00 141.66 ? 35  LEU A C   1 
ATOM   116   O  O   . LEU A 1 35  ? 175.507 216.536 290.417 1.00 143.46 ? 35  LEU A O   1 
ATOM   117   C  CB  . LEU A 1 35  ? 177.921 216.696 292.510 1.00 137.67 ? 35  LEU A CB  1 
ATOM   118   C  CG  . LEU A 1 35  ? 176.991 217.734 293.157 1.00 140.03 ? 35  LEU A CG  1 
ATOM   119   C  CD1 . LEU A 1 35  ? 175.616 217.185 293.537 1.00 142.07 ? 35  LEU A CD1 1 
ATOM   120   C  CD2 . LEU A 1 35  ? 177.670 218.364 294.367 1.00 133.27 ? 35  LEU A CD2 1 
ATOM   121   N  N   . ILE A 1 36  ? 176.119 214.415 290.888 1.00 145.50 ? 36  ILE A N   1 
ATOM   122   C  CA  . ILE A 1 36  ? 174.807 213.839 290.632 1.00 148.64 ? 36  ILE A CA  1 
ATOM   123   C  C   . ILE A 1 36  ? 174.382 213.035 291.850 1.00 147.32 ? 36  ILE A C   1 
ATOM   124   O  O   . ILE A 1 36  ? 175.208 212.435 292.546 1.00 144.18 ? 36  ILE A O   1 
ATOM   125   C  CB  . ILE A 1 36  ? 174.785 212.959 289.360 1.00 147.33 ? 36  ILE A CB  1 
ATOM   126   C  CG1 . ILE A 1 36  ? 175.579 211.670 289.576 1.00 143.80 ? 36  ILE A CG1 1 
ATOM   127   C  CG2 . ILE A 1 36  ? 175.324 213.728 288.162 1.00 144.20 ? 36  ILE A CG2 1 
ATOM   128   C  CD1 . ILE A 1 36  ? 175.149 210.531 288.680 1.00 139.32 ? 36  ILE A CD1 1 
ATOM   129   N  N   . ASN A 1 37  ? 173.080 213.038 292.110 1.00 148.43 ? 37  ASN A N   1 
ATOM   130   C  CA  . ASN A 1 37  ? 172.515 212.372 293.271 1.00 147.45 ? 37  ASN A CA  1 
ATOM   131   C  C   . ASN A 1 37  ? 172.126 210.942 292.906 1.00 146.03 ? 37  ASN A C   1 
ATOM   132   O  O   . ASN A 1 37  ? 172.505 210.417 291.855 1.00 145.39 ? 37  ASN A O   1 
ATOM   133   C  CB  . ASN A 1 37  ? 171.324 213.165 293.803 1.00 147.82 ? 37  ASN A CB  1 
ATOM   134   C  CG  . ASN A 1 37  ? 170.284 213.444 292.733 1.00 146.94 ? 37  ASN A CG  1 
ATOM   135   O  OD1 . ASN A 1 37  ? 170.433 213.032 291.582 1.00 144.99 ? 37  ASN A OD1 1 
ATOM   136   N  ND2 . ASN A 1 37  ? 169.225 214.150 293.109 1.00 148.23 ? 37  ASN A ND2 1 
ATOM   137   N  N   . GLU A 1 38  ? 171.364 210.293 293.788 1.00 146.02 ? 38  GLU A N   1 
ATOM   138   C  CA  . GLU A 1 38  ? 170.858 208.959 293.485 1.00 145.13 ? 38  GLU A CA  1 
ATOM   139   C  C   . GLU A 1 38  ? 169.963 208.979 292.254 1.00 142.46 ? 38  GLU A C   1 
ATOM   140   O  O   . GLU A 1 38  ? 169.989 208.047 291.442 1.00 139.49 ? 38  GLU A O   1 
ATOM   141   C  CB  . GLU A 1 38  ? 170.096 208.403 294.687 1.00 144.91 ? 38  GLU A CB  1 
ATOM   142   C  CG  . GLU A 1 38  ? 170.946 207.598 295.646 1.00 145.94 ? 38  GLU A CG  1 
ATOM   143   C  CD  . GLU A 1 38  ? 171.105 206.153 295.223 1.00 148.42 ? 38  GLU A CD  1 
ATOM   144   O  OE1 . GLU A 1 38  ? 170.987 205.863 294.015 1.00 148.40 ? 38  GLU A OE1 1 
ATOM   145   O  OE2 . GLU A 1 38  ? 171.347 205.301 296.103 1.00 150.52 ? 38  GLU A OE2 1 
ATOM   146   N  N   . ASN A 1 39  ? 169.171 210.035 292.095 1.00 142.60 ? 39  ASN A N   1 
ATOM   147   C  CA  . ASN A 1 39  ? 168.254 210.172 290.968 1.00 142.41 ? 39  ASN A CA  1 
ATOM   148   C  C   . ASN A 1 39  ? 168.958 210.442 289.661 1.00 138.08 ? 39  ASN A C   1 
ATOM   149   O  O   . ASN A 1 39  ? 168.265 210.663 288.657 1.00 136.22 ? 39  ASN A O   1 
ATOM   150   C  CB  . ASN A 1 39  ? 167.244 211.285 291.251 1.00 144.47 ? 39  ASN A CB  1 
ATOM   151   C  CG  . ASN A 1 39  ? 166.407 211.014 292.486 1.00 144.94 ? 39  ASN A CG  1 
ATOM   152   O  OD1 . ASN A 1 39  ? 166.765 211.414 293.594 1.00 143.13 ? 39  ASN A OD1 1 
ATOM   153   N  ND2 . ASN A 1 39  ? 165.283 210.331 292.301 1.00 146.48 ? 39  ASN A ND2 1 
ATOM   154   N  N   . ASP A 1 40  ? 170.290 210.427 289.646 1.00 136.68 ? 40  ASP A N   1 
ATOM   155   C  CA  . ASP A 1 40  ? 171.060 210.640 288.424 1.00 138.12 ? 40  ASP A CA  1 
ATOM   156   C  C   . ASP A 1 40  ? 170.705 211.973 287.773 1.00 137.42 ? 40  ASP A C   1 
ATOM   157   O  O   . ASP A 1 40  ? 170.528 212.066 286.558 1.00 134.20 ? 40  ASP A O   1 
ATOM   158   C  CB  . ASP A 1 40  ? 170.865 209.480 287.448 1.00 137.27 ? 40  ASP A CB  1 
ATOM   159   C  CG  . ASP A 1 40  ? 171.181 208.138 288.074 1.00 139.56 ? 40  ASP A CG  1 
ATOM   160   O  OD1 . ASP A 1 40  ? 171.005 207.105 287.396 1.00 142.92 ? 40  ASP A OD1 1 
ATOM   161   O  OD2 . ASP A 1 40  ? 171.609 208.118 289.245 1.00 137.73 ? 40  ASP A OD2 1 
ATOM   162   N  N   . GLU A 1 41  ? 170.592 213.011 288.594 1.00 141.51 ? 41  GLU A N   1 
ATOM   163   C  CA  . GLU A 1 41  ? 170.312 214.364 288.138 1.00 146.96 ? 41  GLU A CA  1 
ATOM   164   C  C   . GLU A 1 41  ? 171.488 215.273 288.473 1.00 151.53 ? 41  GLU A C   1 
ATOM   165   O  O   . GLU A 1 41  ? 172.011 215.240 289.591 1.00 151.97 ? 41  GLU A O   1 
ATOM   166   C  CB  . GLU A 1 41  ? 169.029 214.902 288.776 1.00 147.72 ? 41  GLU A CB  1 
ATOM   167   C  CG  . GLU A 1 41  ? 167.830 213.981 288.624 1.00 143.29 ? 41  GLU A CG  1 
ATOM   168   C  CD  . GLU A 1 41  ? 166.698 214.337 289.569 1.00 144.15 ? 41  GLU A CD  1 
ATOM   169   O  OE1 . GLU A 1 41  ? 166.984 214.740 290.716 1.00 146.25 ? 41  GLU A OE1 1 
ATOM   170   O  OE2 . GLU A 1 41  ? 165.522 214.215 289.166 1.00 141.79 ? 41  GLU A OE2 1 
ATOM   171   N  N   . VAL A 1 42  ? 171.900 216.082 287.501 1.00 151.31 ? 42  VAL A N   1 
ATOM   172   C  CA  . VAL A 1 42  ? 173.072 216.940 287.652 1.00 152.91 ? 42  VAL A CA  1 
ATOM   173   C  C   . VAL A 1 42  ? 172.721 218.114 288.556 1.00 153.12 ? 42  VAL A C   1 
ATOM   174   O  O   . VAL A 1 42  ? 171.778 218.862 288.279 1.00 153.51 ? 42  VAL A O   1 
ATOM   175   C  CB  . VAL A 1 42  ? 173.577 217.428 286.288 1.00 153.42 ? 42  VAL A CB  1 
ATOM   176   C  CG1 . VAL A 1 42  ? 174.849 218.242 286.453 1.00 151.30 ? 42  VAL A CG1 1 
ATOM   177   C  CG2 . VAL A 1 42  ? 173.808 216.247 285.360 1.00 149.03 ? 42  VAL A CG2 1 
ATOM   178   N  N   . MET A 1 43  ? 173.494 218.289 289.631 1.00 150.86 ? 43  MET A N   1 
ATOM   179   C  CA  . MET A 1 43  ? 173.262 219.351 290.603 1.00 148.36 ? 43  MET A CA  1 
ATOM   180   C  C   . MET A 1 43  ? 174.499 220.212 290.839 1.00 144.61 ? 43  MET A C   1 
ATOM   181   O  O   . MET A 1 43  ? 174.526 220.981 291.807 1.00 141.38 ? 43  MET A O   1 
ATOM   182   C  CB  . MET A 1 43  ? 172.780 218.757 291.934 1.00 145.13 ? 43  MET A CB  1 
ATOM   183   C  CG  . MET A 1 43  ? 171.787 219.593 292.776 1.00 143.73 ? 43  MET A CG  1 
ATOM   184   S  SD  . MET A 1 43  ? 170.420 220.573 292.085 1.00 148.79 ? 43  MET A SD  1 
ATOM   185   C  CE  . MET A 1 43  ? 169.929 219.692 290.604 1.00 148.99 ? 43  MET A CE  1 
ATOM   186   N  N   . PHE A 1 44  ? 175.526 220.098 289.996 1.00 144.65 ? 44  PHE A N   1 
ATOM   187   C  CA  . PHE A 1 44  ? 176.678 220.985 290.077 1.00 144.21 ? 44  PHE A CA  1 
ATOM   188   C  C   . PHE A 1 44  ? 177.246 221.192 288.680 1.00 145.33 ? 44  PHE A C   1 
ATOM   189   O  O   . PHE A 1 44  ? 177.295 220.263 287.869 1.00 143.83 ? 44  PHE A O   1 
ATOM   190   C  CB  . PHE A 1 44  ? 177.764 220.446 291.017 1.00 141.70 ? 44  PHE A CB  1 
ATOM   191   C  CG  . PHE A 1 44  ? 178.667 221.516 291.562 1.00 143.27 ? 44  PHE A CG  1 
ATOM   192   C  CD1 . PHE A 1 44  ? 178.374 222.140 292.763 1.00 144.92 ? 44  PHE A CD1 1 
ATOM   193   C  CD2 . PHE A 1 44  ? 179.792 221.917 290.864 1.00 144.68 ? 44  PHE A CD2 1 
ATOM   194   C  CE1 . PHE A 1 44  ? 179.192 223.133 293.264 1.00 146.45 ? 44  PHE A CE1 1 
ATOM   195   C  CE2 . PHE A 1 44  ? 180.611 222.912 291.362 1.00 143.40 ? 44  PHE A CE2 1 
ATOM   196   C  CZ  . PHE A 1 44  ? 180.310 223.519 292.564 1.00 144.24 ? 44  PHE A CZ  1 
ATOM   197   N  N   . PHE A 1 45  ? 177.675 222.425 288.409 1.00 148.28 ? 45  PHE A N   1 
ATOM   198   C  CA  . PHE A 1 45  ? 178.087 222.824 287.070 1.00 149.54 ? 45  PHE A CA  1 
ATOM   199   C  C   . PHE A 1 45  ? 178.909 224.102 287.185 1.00 147.05 ? 45  PHE A C   1 
ATOM   200   O  O   . PHE A 1 45  ? 178.538 225.007 287.934 1.00 146.00 ? 45  PHE A O   1 
ATOM   201   C  CB  . PHE A 1 45  ? 176.854 223.033 286.180 1.00 152.79 ? 45  PHE A CB  1 
ATOM   202   C  CG  . PHE A 1 45  ? 177.144 223.024 284.699 1.00 153.73 ? 45  PHE A CG  1 
ATOM   203   C  CD1 . PHE A 1 45  ? 177.057 221.849 283.974 1.00 154.88 ? 45  PHE A CD1 1 
ATOM   204   C  CD2 . PHE A 1 45  ? 177.458 224.191 284.033 1.00 150.29 ? 45  PHE A CD2 1 
ATOM   205   C  CE1 . PHE A 1 45  ? 177.305 221.835 282.609 1.00 152.53 ? 45  PHE A CE1 1 
ATOM   206   C  CE2 . PHE A 1 45  ? 177.705 224.179 282.670 1.00 149.86 ? 45  PHE A CE2 1 
ATOM   207   C  CZ  . PHE A 1 45  ? 177.628 222.998 281.963 1.00 149.72 ? 45  PHE A CZ  1 
ATOM   208   N  N   . ASN A 1 46  ? 179.999 224.187 286.435 1.00 143.47 ? 46  ASN A N   1 
ATOM   209   C  CA  . ASN A 1 46  ? 180.978 225.244 286.630 1.00 140.69 ? 46  ASN A CA  1 
ATOM   210   C  C   . ASN A 1 46  ? 181.354 225.891 285.305 1.00 141.33 ? 46  ASN A C   1 
ATOM   211   O  O   . ASN A 1 46  ? 181.035 225.362 284.235 1.00 140.05 ? 46  ASN A O   1 
ATOM   212   C  CB  . ASN A 1 46  ? 182.228 224.698 287.342 1.00 138.18 ? 46  ASN A CB  1 
ATOM   213   C  CG  . ASN A 1 46  ? 183.144 223.922 286.420 1.00 137.18 ? 46  ASN A CG  1 
ATOM   214   O  OD1 . ASN A 1 46  ? 182.732 223.440 285.370 1.00 135.97 ? 46  ASN A OD1 1 
ATOM   215   N  ND2 . ASN A 1 46  ? 184.404 223.796 286.817 1.00 137.08 ? 46  ASN A ND2 1 
ATOM   216   N  N   . PRO A 1 47  ? 182.014 227.060 285.343 1.00 144.90 ? 47  PRO A N   1 
ATOM   217   C  CA  . PRO A 1 47  ? 182.412 227.723 284.085 1.00 146.21 ? 47  PRO A CA  1 
ATOM   218   C  C   . PRO A 1 47  ? 183.211 226.844 283.136 1.00 144.70 ? 47  PRO A C   1 
ATOM   219   O  O   . PRO A 1 47  ? 183.070 226.967 281.911 1.00 145.79 ? 47  PRO A O   1 
ATOM   220   C  CB  . PRO A 1 47  ? 183.232 228.922 284.578 1.00 146.21 ? 47  PRO A CB  1 
ATOM   221   C  CG  . PRO A 1 47  ? 182.637 229.250 285.899 1.00 146.86 ? 47  PRO A CG  1 
ATOM   222   C  CD  . PRO A 1 47  ? 182.228 227.935 286.511 1.00 146.05 ? 47  PRO A CD  1 
ATOM   223   N  N   . ALA A 1 48  ? 184.057 225.961 283.665 1.00 141.81 ? 48  ALA A N   1 
ATOM   224   C  CA  . ALA A 1 48  ? 184.737 225.000 282.806 1.00 137.46 ? 48  ALA A CA  1 
ATOM   225   C  C   . ALA A 1 48  ? 183.737 224.072 282.135 1.00 136.30 ? 48  ALA A C   1 
ATOM   226   O  O   . ALA A 1 48  ? 183.887 223.733 280.958 1.00 132.38 ? 48  ALA A O   1 
ATOM   227   C  CB  . ALA A 1 48  ? 185.757 224.200 283.611 1.00 132.83 ? 48  ALA A CB  1 
ATOM   228   N  N   . ALA A 1 49  ? 182.716 223.636 282.875 1.00 138.23 ? 49  ALA A N   1 
ATOM   229   C  CA  . ALA A 1 49  ? 181.651 222.857 282.258 1.00 140.77 ? 49  ALA A CA  1 
ATOM   230   C  C   . ALA A 1 49  ? 180.936 223.676 281.194 1.00 138.14 ? 49  ALA A C   1 
ATOM   231   O  O   . ALA A 1 49  ? 180.463 223.129 280.193 1.00 136.18 ? 49  ALA A O   1 
ATOM   232   C  CB  . ALA A 1 49  ? 180.667 222.372 283.318 1.00 145.10 ? 49  ALA A CB  1 
ATOM   233   N  N   . GLU A 1 50  ? 180.838 224.991 281.395 1.00 139.99 ? 50  GLU A N   1 
ATOM   234   C  CA  . GLU A 1 50  ? 180.288 225.844 280.348 1.00 141.68 ? 50  GLU A CA  1 
ATOM   235   C  C   . GLU A 1 50  ? 181.154 225.788 279.098 1.00 138.99 ? 50  GLU A C   1 
ATOM   236   O  O   . GLU A 1 50  ? 180.643 225.705 277.977 1.00 140.63 ? 50  GLU A O   1 
ATOM   237   C  CB  . GLU A 1 50  ? 180.161 227.284 280.843 1.00 144.37 ? 50  GLU A CB  1 
ATOM   238   C  CG  . GLU A 1 50  ? 179.581 227.461 282.240 1.00 144.31 ? 50  GLU A CG  1 
ATOM   239   C  CD  . GLU A 1 50  ? 178.078 227.366 282.293 1.00 148.05 ? 50  GLU A CD  1 
ATOM   240   O  OE1 . GLU A 1 50  ? 177.433 227.433 281.228 1.00 149.57 ? 50  GLU A OE1 1 
ATOM   241   O  OE2 . GLU A 1 50  ? 177.542 227.244 283.416 1.00 149.73 ? 50  GLU A OE2 1 
ATOM   242   N  N   . LYS A 1 51  ? 182.474 225.848 279.269 1.00 136.19 ? 51  LYS A N   1 
ATOM   243   C  CA  . LYS A 1 51  ? 183.349 225.774 278.105 1.00 134.79 ? 51  LYS A CA  1 
ATOM   244   C  C   . LYS A 1 51  ? 183.288 224.405 277.439 1.00 134.23 ? 51  LYS A C   1 
ATOM   245   O  O   . LYS A 1 51  ? 183.350 224.311 276.208 1.00 136.81 ? 51  LYS A O   1 
ATOM   246   C  CB  . LYS A 1 51  ? 184.780 226.128 278.506 1.00 134.75 ? 51  LYS A CB  1 
ATOM   247   C  CG  . LYS A 1 51  ? 185.842 225.209 277.947 1.00 135.16 ? 51  LYS A CG  1 
ATOM   248   C  CD  . LYS A 1 51  ? 187.210 225.591 278.483 1.00 134.29 ? 51  LYS A CD  1 
ATOM   249   C  CE  . LYS A 1 51  ? 187.347 225.257 279.962 1.00 129.38 ? 51  LYS A CE  1 
ATOM   250   N  NZ  . LYS A 1 51  ? 187.034 223.832 280.248 1.00 130.64 ? 51  LYS A NZ  1 
ATOM   251   N  N   . LEU A 1 52  ? 183.143 223.341 278.227 1.00 133.07 ? 52  LEU A N   1 
ATOM   252   C  CA  . LEU A 1 52  ? 183.224 221.989 277.683 1.00 135.64 ? 52  LEU A CA  1 
ATOM   253   C  C   . LEU A 1 52  ? 181.893 221.531 277.092 1.00 138.36 ? 52  LEU A C   1 
ATOM   254   O  O   . LEU A 1 52  ? 181.793 221.271 275.888 1.00 137.43 ? 52  LEU A O   1 
ATOM   255   C  CB  . LEU A 1 52  ? 183.694 221.023 278.772 1.00 136.63 ? 52  LEU A CB  1 
ATOM   256   C  CG  . LEU A 1 52  ? 185.139 221.214 279.236 1.00 132.18 ? 52  LEU A CG  1 
ATOM   257   C  CD1 . LEU A 1 52  ? 185.287 220.769 280.680 1.00 132.79 ? 52  LEU A CD1 1 
ATOM   258   C  CD2 . LEU A 1 52  ? 186.118 220.468 278.344 1.00 119.00 ? 52  LEU A CD2 1 
ATOM   259   N  N   . TRP A 1 53  ? 180.859 221.409 277.928 1.00 141.15 ? 53  TRP A N   1 
ATOM   260   C  CA  . TRP A 1 53  ? 179.567 220.935 277.445 1.00 143.61 ? 53  TRP A CA  1 
ATOM   261   C  C   . TRP A 1 53  ? 178.890 221.959 276.543 1.00 144.87 ? 53  TRP A C   1 
ATOM   262   O  O   . TRP A 1 53  ? 178.284 221.593 275.530 1.00 144.44 ? 53  TRP A O   1 
ATOM   263   C  CB  . TRP A 1 53  ? 178.656 220.586 278.622 1.00 147.28 ? 53  TRP A CB  1 
ATOM   264   C  CG  . TRP A 1 53  ? 178.761 219.157 279.050 1.00 148.71 ? 53  TRP A CG  1 
ATOM   265   C  CD1 . TRP A 1 53  ? 178.171 218.081 278.454 1.00 145.57 ? 53  TRP A CD1 1 
ATOM   266   C  CD2 . TRP A 1 53  ? 179.492 218.644 280.171 1.00 151.81 ? 53  TRP A CD2 1 
ATOM   267   N  NE1 . TRP A 1 53  ? 178.495 216.930 279.129 1.00 145.98 ? 53  TRP A NE1 1 
ATOM   268   C  CE2 . TRP A 1 53  ? 179.303 217.248 280.188 1.00 150.31 ? 53  TRP A CE2 1 
ATOM   269   C  CE3 . TRP A 1 53  ? 180.288 219.229 281.161 1.00 150.11 ? 53  TRP A CE3 1 
ATOM   270   C  CZ2 . TRP A 1 53  ? 179.881 216.428 281.154 1.00 148.08 ? 53  TRP A CZ2 1 
ATOM   271   C  CZ3 . TRP A 1 53  ? 180.862 218.412 282.120 1.00 147.12 ? 53  TRP A CZ3 1 
ATOM   272   C  CH2 . TRP A 1 53  ? 180.655 217.027 282.109 1.00 145.89 ? 53  TRP A CH2 1 
ATOM   273   N  N   . GLY A 1 54  ? 178.988 223.240 276.890 1.00 145.94 ? 54  GLY A N   1 
ATOM   274   C  CA  . GLY A 1 54  ? 178.371 224.293 276.117 1.00 149.12 ? 54  GLY A CA  1 
ATOM   275   C  C   . GLY A 1 54  ? 176.949 224.627 276.507 1.00 152.14 ? 54  GLY A C   1 
ATOM   276   O  O   . GLY A 1 54  ? 176.362 225.544 275.918 1.00 151.33 ? 54  GLY A O   1 
ATOM   277   N  N   . TYR A 1 55  ? 176.374 223.919 277.474 1.00 152.55 ? 55  TYR A N   1 
ATOM   278   C  CA  . TYR A 1 55  ? 175.018 224.177 277.937 1.00 153.08 ? 55  TYR A CA  1 
ATOM   279   C  C   . TYR A 1 55  ? 175.069 225.019 279.203 1.00 152.35 ? 55  TYR A C   1 
ATOM   280   O  O   . TYR A 1 55  ? 175.858 224.738 280.109 1.00 149.97 ? 55  TYR A O   1 
ATOM   281   C  CB  . TYR A 1 55  ? 174.272 222.868 278.200 1.00 150.21 ? 55  TYR A CB  1 
ATOM   282   C  CG  . TYR A 1 55  ? 174.032 222.044 276.957 1.00 150.97 ? 55  TYR A CG  1 
ATOM   283   C  CD1 . TYR A 1 55  ? 174.986 221.144 276.500 1.00 149.13 ? 55  TYR A CD1 1 
ATOM   284   C  CD2 . TYR A 1 55  ? 172.850 222.168 276.238 1.00 151.71 ? 55  TYR A CD2 1 
ATOM   285   C  CE1 . TYR A 1 55  ? 174.770 220.389 275.364 1.00 147.81 ? 55  TYR A CE1 1 
ATOM   286   C  CE2 . TYR A 1 55  ? 172.625 221.416 275.101 1.00 151.43 ? 55  TYR A CE2 1 
ATOM   287   C  CZ  . TYR A 1 55  ? 173.588 220.529 274.668 1.00 149.36 ? 55  TYR A CZ  1 
ATOM   288   O  OH  . TYR A 1 55  ? 173.368 219.780 273.536 1.00 149.79 ? 55  TYR A OH  1 
ATOM   289   N  N   . LYS A 1 56  ? 174.232 226.051 279.257 1.00 152.64 ? 56  LYS A N   1 
ATOM   290   C  CA  . LYS A 1 56  ? 174.199 226.919 280.421 1.00 152.52 ? 56  LYS A CA  1 
ATOM   291   C  C   . LYS A 1 56  ? 173.711 226.150 281.642 1.00 154.01 ? 56  LYS A C   1 
ATOM   292   O  O   . LYS A 1 56  ? 172.959 225.177 281.539 1.00 154.05 ? 56  LYS A O   1 
ATOM   293   C  CB  . LYS A 1 56  ? 173.297 228.126 280.167 1.00 151.46 ? 56  LYS A CB  1 
ATOM   294   C  CG  . LYS A 1 56  ? 173.788 229.048 279.064 1.00 147.77 ? 56  LYS A CG  1 
ATOM   295   C  CD  . LYS A 1 56  ? 175.177 229.585 279.369 1.00 144.41 ? 56  LYS A CD  1 
ATOM   296   C  CE  . LYS A 1 56  ? 175.159 230.515 280.572 1.00 141.52 ? 56  LYS A CE  1 
ATOM   297   N  NZ  . LYS A 1 56  ? 174.363 231.746 280.309 1.00 138.71 ? 56  LYS A NZ  1 
ATOM   298   N  N   . ARG A 1 57  ? 174.157 226.603 282.817 1.00 155.06 ? 57  ARG A N   1 
ATOM   299   C  CA  . ARG A 1 57  ? 173.792 225.926 284.057 1.00 156.48 ? 57  ARG A CA  1 
ATOM   300   C  C   . ARG A 1 57  ? 172.284 225.917 284.268 1.00 157.93 ? 57  ARG A C   1 
ATOM   301   O  O   . ARG A 1 57  ? 171.753 224.993 284.894 1.00 156.25 ? 57  ARG A O   1 
ATOM   302   C  CB  . ARG A 1 57  ? 174.501 226.585 285.243 1.00 157.36 ? 57  ARG A CB  1 
ATOM   303   C  CG  . ARG A 1 57  ? 173.958 227.953 285.627 1.00 156.81 ? 57  ARG A CG  1 
ATOM   304   C  CD  . ARG A 1 57  ? 174.623 228.478 286.890 1.00 153.21 ? 57  ARG A CD  1 
ATOM   305   N  NE  . ARG A 1 57  ? 175.885 229.150 286.604 1.00 153.67 ? 57  ARG A NE  1 
ATOM   306   C  CZ  . ARG A 1 57  ? 175.989 230.411 286.207 1.00 152.67 ? 57  ARG A CZ  1 
ATOM   307   N  NH1 . ARG A 1 57  ? 174.921 231.173 286.035 1.00 150.95 ? 57  ARG A NH1 1 
ATOM   308   N  NH2 . ARG A 1 57  ? 177.196 230.920 285.975 1.00 151.34 ? 57  ARG A NH2 1 
ATOM   309   N  N   . GLU A 1 58  ? 171.576 226.918 283.739 1.00 159.56 ? 58  GLU A N   1 
ATOM   310   C  CA  . GLU A 1 58  ? 170.122 226.919 283.818 1.00 160.22 ? 58  GLU A CA  1 
ATOM   311   C  C   . GLU A 1 58  ? 169.506 225.790 283.003 1.00 159.94 ? 58  GLU A C   1 
ATOM   312   O  O   . GLU A 1 58  ? 168.338 225.451 283.217 1.00 159.66 ? 58  GLU A O   1 
ATOM   313   C  CB  . GLU A 1 58  ? 169.567 228.265 283.349 1.00 160.28 ? 58  GLU A CB  1 
ATOM   314   C  CG  . GLU A 1 58  ? 169.797 229.409 284.324 1.00 160.58 ? 58  GLU A CG  1 
ATOM   315   C  CD  . GLU A 1 58  ? 171.184 230.010 284.202 1.00 159.15 ? 58  GLU A CD  1 
ATOM   316   O  OE1 . GLU A 1 58  ? 171.845 229.780 283.168 1.00 156.70 ? 58  GLU A OE1 1 
ATOM   317   O  OE2 . GLU A 1 58  ? 171.613 230.714 285.141 1.00 158.39 ? 58  GLU A OE2 1 
ATOM   318   N  N   . GLU A 1 59  ? 170.265 225.204 282.079 1.00 158.71 ? 59  GLU A N   1 
ATOM   319   C  CA  . GLU A 1 59  ? 169.798 224.079 281.282 1.00 156.08 ? 59  GLU A CA  1 
ATOM   320   C  C   . GLU A 1 59  ? 170.257 222.736 281.823 1.00 154.23 ? 59  GLU A C   1 
ATOM   321   O  O   . GLU A 1 59  ? 169.599 221.721 281.571 1.00 152.40 ? 59  GLU A O   1 
ATOM   322   C  CB  . GLU A 1 59  ? 170.281 224.221 279.835 1.00 155.24 ? 59  GLU A CB  1 
ATOM   323   C  CG  . GLU A 1 59  ? 170.089 225.610 279.251 1.00 157.47 ? 59  GLU A CG  1 
ATOM   324   C  CD  . GLU A 1 59  ? 170.718 225.755 277.881 1.00 156.65 ? 59  GLU A CD  1 
ATOM   325   O  OE1 . GLU A 1 59  ? 171.958 225.650 277.782 1.00 154.87 ? 59  GLU A OE1 1 
ATOM   326   O  OE2 . GLU A 1 59  ? 169.973 225.977 276.903 1.00 158.88 ? 59  GLU A OE2 1 
ATOM   327   N  N   . VAL A 1 60  ? 171.362 222.706 282.563 1.00 155.28 ? 60  VAL A N   1 
ATOM   328   C  CA  . VAL A 1 60  ? 171.910 221.449 283.061 1.00 156.40 ? 60  VAL A CA  1 
ATOM   329   C  C   . VAL A 1 60  ? 171.406 221.133 284.464 1.00 155.34 ? 60  VAL A C   1 
ATOM   330   O  O   . VAL A 1 60  ? 171.169 219.968 284.792 1.00 152.43 ? 60  VAL A O   1 
ATOM   331   C  CB  . VAL A 1 60  ? 173.449 221.493 283.008 1.00 155.43 ? 60  VAL A CB  1 
ATOM   332   C  CG1 . VAL A 1 60  ? 174.023 220.092 283.147 1.00 152.45 ? 60  VAL A CG1 1 
ATOM   333   C  CG2 . VAL A 1 60  ? 173.914 222.131 281.710 1.00 152.06 ? 60  VAL A CG2 1 
ATOM   334   N  N   . ILE A 1 61  ? 171.242 222.150 285.313 1.00 156.50 ? 61  ILE A N   1 
ATOM   335   C  CA  . ILE A 1 61  ? 170.737 221.912 286.660 1.00 156.69 ? 61  ILE A CA  1 
ATOM   336   C  C   . ILE A 1 61  ? 169.308 221.400 286.579 1.00 155.70 ? 61  ILE A C   1 
ATOM   337   O  O   . ILE A 1 61  ? 168.452 221.993 285.910 1.00 154.56 ? 61  ILE A O   1 
ATOM   338   C  CB  . ILE A 1 61  ? 170.835 223.189 287.508 1.00 154.12 ? 61  ILE A CB  1 
ATOM   339   C  CG1 . ILE A 1 61  ? 172.298 223.595 287.694 1.00 151.09 ? 61  ILE A CG1 1 
ATOM   340   C  CG2 . ILE A 1 61  ? 170.161 222.988 288.858 1.00 150.45 ? 61  ILE A CG2 1 
ATOM   341   C  CD1 . ILE A 1 61  ? 173.124 222.573 288.444 1.00 147.93 ? 61  ILE A CD1 1 
ATOM   342   N  N   . GLY A 1 62  ? 169.045 220.288 287.261 1.00 154.71 ? 62  GLY A N   1 
ATOM   343   C  CA  . GLY A 1 62  ? 167.767 219.620 287.176 1.00 152.87 ? 62  GLY A CA  1 
ATOM   344   C  C   . GLY A 1 62  ? 167.655 218.608 286.059 1.00 151.65 ? 62  GLY A C   1 
ATOM   345   O  O   . GLY A 1 62  ? 166.632 217.918 285.971 1.00 149.92 ? 62  GLY A O   1 
ATOM   346   N  N   . ASN A 1 63  ? 168.669 218.496 285.207 1.00 150.58 ? 63  ASN A N   1 
ATOM   347   C  CA  . ASN A 1 63  ? 168.659 217.543 284.109 1.00 147.56 ? 63  ASN A CA  1 
ATOM   348   C  C   . ASN A 1 63  ? 169.312 216.233 284.528 1.00 146.02 ? 63  ASN A C   1 
ATOM   349   O  O   . ASN A 1 63  ? 170.165 216.195 285.417 1.00 147.84 ? 63  ASN A O   1 
ATOM   350   C  CB  . ASN A 1 63  ? 169.382 218.110 282.889 1.00 145.83 ? 63  ASN A CB  1 
ATOM   351   C  CG  . ASN A 1 63  ? 169.003 217.398 281.613 1.00 146.66 ? 63  ASN A CG  1 
ATOM   352   O  OD1 . ASN A 1 63  ? 168.972 216.168 281.562 1.00 142.16 ? 63  ASN A OD1 1 
ATOM   353   N  ND2 . ASN A 1 63  ? 168.711 218.166 280.571 1.00 149.76 ? 63  ASN A ND2 1 
ATOM   354   N  N   . ASN A 1 64  ? 168.905 215.155 283.865 1.00 140.19 ? 64  ASN A N   1 
ATOM   355   C  CA  . ASN A 1 64  ? 169.434 213.842 284.187 1.00 135.01 ? 64  ASN A CA  1 
ATOM   356   C  C   . ASN A 1 64  ? 170.859 213.689 283.665 1.00 133.37 ? 64  ASN A C   1 
ATOM   357   O  O   . ASN A 1 64  ? 171.328 214.449 282.814 1.00 132.24 ? 64  ASN A O   1 
ATOM   358   C  CB  . ASN A 1 64  ? 168.541 212.747 283.609 1.00 132.51 ? 64  ASN A CB  1 
ATOM   359   C  CG  . ASN A 1 64  ? 168.856 211.381 284.182 1.00 133.11 ? 64  ASN A CG  1 
ATOM   360   O  OD1 . ASN A 1 64  ? 169.678 210.645 283.638 1.00 133.79 ? 64  ASN A OD1 1 
ATOM   361   N  ND2 . ASN A 1 64  ? 168.223 211.045 285.298 1.00 132.49 ? 64  ASN A ND2 1 
ATOM   362   N  N   . ILE A 1 65  ? 171.549 212.675 284.193 1.00 133.35 ? 65  ILE A N   1 
ATOM   363   C  CA  . ILE A 1 65  ? 172.913 212.388 283.764 1.00 134.21 ? 65  ILE A CA  1 
ATOM   364   C  C   . ILE A 1 65  ? 172.958 212.077 282.274 1.00 134.45 ? 65  ILE A C   1 
ATOM   365   O  O   . ILE A 1 65  ? 173.951 212.376 281.597 1.00 133.00 ? 65  ILE A O   1 
ATOM   366   C  CB  . ILE A 1 65  ? 173.494 211.235 284.610 1.00 132.06 ? 65  ILE A CB  1 
ATOM   367   C  CG1 . ILE A 1 65  ? 174.942 210.947 284.223 1.00 129.70 ? 65  ILE A CG1 1 
ATOM   368   C  CG2 . ILE A 1 65  ? 172.661 209.983 284.461 1.00 131.14 ? 65  ILE A CG2 1 
ATOM   369   C  CD1 . ILE A 1 65  ? 175.573 209.867 285.058 1.00 127.21 ? 65  ILE A CD1 1 
ATOM   370   N  N   . ASP A 1 66  ? 171.878 211.509 281.731 1.00 135.63 ? 66  ASP A N   1 
ATOM   371   C  CA  . ASP A 1 66  ? 171.847 211.145 280.319 1.00 136.34 ? 66  ASP A CA  1 
ATOM   372   C  C   . ASP A 1 66  ? 172.056 212.345 279.408 1.00 134.53 ? 66  ASP A C   1 
ATOM   373   O  O   . ASP A 1 66  ? 172.458 212.169 278.253 1.00 135.68 ? 66  ASP A O   1 
ATOM   374   C  CB  . ASP A 1 66  ? 170.522 210.459 279.984 1.00 137.11 ? 66  ASP A CB  1 
ATOM   375   C  CG  . ASP A 1 66  ? 170.487 209.919 278.567 1.00 136.61 ? 66  ASP A CG  1 
ATOM   376   O  OD1 . ASP A 1 66  ? 171.385 209.130 278.208 1.00 136.61 ? 66  ASP A OD1 1 
ATOM   377   O  OD2 . ASP A 1 66  ? 169.561 210.285 277.813 1.00 135.08 ? 66  ASP A OD2 1 
ATOM   378   N  N   . MET A 1 67  ? 171.797 213.558 279.899 1.00 130.40 ? 67  MET A N   1 
ATOM   379   C  CA  . MET A 1 67  ? 172.060 214.745 279.094 1.00 134.04 ? 67  MET A CA  1 
ATOM   380   C  C   . MET A 1 67  ? 173.537 214.847 278.745 1.00 136.10 ? 67  MET A C   1 
ATOM   381   O  O   . MET A 1 67  ? 173.895 215.176 277.608 1.00 135.36 ? 67  MET A O   1 
ATOM   382   C  CB  . MET A 1 67  ? 171.598 215.996 279.838 1.00 139.77 ? 67  MET A CB  1 
ATOM   383   C  CG  . MET A 1 67  ? 171.830 217.294 279.083 1.00 145.67 ? 67  MET A CG  1 
ATOM   384   S  SD  . MET A 1 67  ? 171.828 218.731 280.172 1.00 153.94 ? 67  MET A SD  1 
ATOM   385   C  CE  . MET A 1 67  ? 171.848 220.067 278.980 1.00 149.54 ? 67  MET A CE  1 
ATOM   386   N  N   . LEU A 1 68  ? 174.411 214.555 279.706 1.00 137.04 ? 68  LEU A N   1 
ATOM   387   C  CA  . LEU A 1 68  ? 175.842 214.657 279.460 1.00 139.06 ? 68  LEU A CA  1 
ATOM   388   C  C   . LEU A 1 68  ? 176.371 213.522 278.597 1.00 137.31 ? 68  LEU A C   1 
ATOM   389   O  O   . LEU A 1 68  ? 177.511 213.602 278.130 1.00 138.96 ? 68  LEU A O   1 
ATOM   390   C  CB  . LEU A 1 68  ? 176.598 214.691 280.788 1.00 140.67 ? 68  LEU A CB  1 
ATOM   391   C  CG  . LEU A 1 68  ? 175.997 215.570 281.889 1.00 140.73 ? 68  LEU A CG  1 
ATOM   392   C  CD1 . LEU A 1 68  ? 176.710 215.333 283.212 1.00 140.41 ? 68  LEU A CD1 1 
ATOM   393   C  CD2 . LEU A 1 68  ? 176.045 217.040 281.501 1.00 141.03 ? 68  LEU A CD2 1 
ATOM   394   N  N   . ILE A 1 69  ? 175.578 212.481 278.371 1.00 136.34 ? 69  ILE A N   1 
ATOM   395   C  CA  . ILE A 1 69  ? 176.041 211.290 277.666 1.00 140.66 ? 69  ILE A CA  1 
ATOM   396   C  C   . ILE A 1 69  ? 175.956 211.508 276.159 1.00 143.89 ? 69  ILE A C   1 
ATOM   397   O  O   . ILE A 1 69  ? 174.930 211.990 275.658 1.00 141.98 ? 69  ILE A O   1 
ATOM   398   C  CB  . ILE A 1 69  ? 175.240 210.052 278.099 1.00 141.54 ? 69  ILE A CB  1 
ATOM   399   C  CG1 . ILE A 1 69  ? 175.251 209.933 279.624 1.00 139.66 ? 69  ILE A CG1 1 
ATOM   400   C  CG2 . ILE A 1 69  ? 175.803 208.793 277.457 1.00 139.41 ? 69  ILE A CG2 1 
ATOM   401   C  CD1 . ILE A 1 69  ? 176.639 209.999 280.231 1.00 132.37 ? 69  ILE A CD1 1 
ATOM   402   N  N   . PRO A 1 70  ? 177.008 211.185 275.408 1.00 146.47 ? 70  PRO A N   1 
ATOM   403   C  CA  . PRO A 1 70  ? 176.943 211.307 273.948 1.00 145.66 ? 70  PRO A CA  1 
ATOM   404   C  C   . PRO A 1 70  ? 175.985 210.291 273.345 1.00 143.47 ? 70  PRO A C   1 
ATOM   405   O  O   . PRO A 1 70  ? 175.629 209.283 273.958 1.00 142.19 ? 70  PRO A O   1 
ATOM   406   C  CB  . PRO A 1 70  ? 178.386 211.041 273.499 1.00 141.46 ? 70  PRO A CB  1 
ATOM   407   C  CG  . PRO A 1 70  ? 179.222 211.221 274.731 1.00 136.72 ? 70  PRO A CG  1 
ATOM   408   C  CD  . PRO A 1 70  ? 178.351 210.802 275.870 1.00 140.37 ? 70  PRO A CD  1 
ATOM   409   N  N   . ARG A 1 71  ? 175.578 210.575 272.106 1.00 140.38 ? 71  ARG A N   1 
ATOM   410   C  CA  . ARG A 1 71  ? 174.564 209.760 271.442 1.00 137.61 ? 71  ARG A CA  1 
ATOM   411   C  C   . ARG A 1 71  ? 175.019 208.312 271.300 1.00 137.12 ? 71  ARG A C   1 
ATOM   412   O  O   . ARG A 1 71  ? 174.280 207.381 271.642 1.00 135.77 ? 71  ARG A O   1 
ATOM   413   C  CB  . ARG A 1 71  ? 174.237 210.360 270.075 1.00 140.69 ? 71  ARG A CB  1 
ATOM   414   C  CG  . ARG A 1 71  ? 173.655 211.763 270.141 1.00 141.54 ? 71  ARG A CG  1 
ATOM   415   C  CD  . ARG A 1 71  ? 173.533 212.382 268.757 1.00 144.14 ? 71  ARG A CD  1 
ATOM   416   N  NE  . ARG A 1 71  ? 172.538 211.705 267.935 1.00 147.19 ? 71  ARG A NE  1 
ATOM   417   C  CZ  . ARG A 1 71  ? 171.241 211.980 267.952 1.00 147.65 ? 71  ARG A CZ  1 
ATOM   418   N  NH1 . ARG A 1 71  ? 170.743 212.918 268.741 1.00 146.23 ? 71  ARG A NH1 1 
ATOM   419   N  NH2 . ARG A 1 71  ? 170.422 211.299 267.155 1.00 146.88 ? 71  ARG A NH2 1 
ATOM   420   N  N   . ASP A 1 72  ? 176.254 208.105 270.840 1.00 139.01 ? 72  ASP A N   1 
ATOM   421   C  CA  . ASP A 1 72  ? 176.743 206.783 270.459 1.00 137.13 ? 72  ASP A CA  1 
ATOM   422   C  C   . ASP A 1 72  ? 176.816 205.810 271.630 1.00 135.50 ? 72  ASP A C   1 
ATOM   423   O  O   . ASP A 1 72  ? 177.202 204.650 271.452 1.00 133.82 ? 72  ASP A O   1 
ATOM   424   C  CB  . ASP A 1 72  ? 178.119 206.901 269.800 1.00 135.73 ? 72  ASP A CB  1 
ATOM   425   C  CG  . ASP A 1 72  ? 179.037 207.863 270.531 1.00 136.46 ? 72  ASP A CG  1 
ATOM   426   O  OD1 . ASP A 1 72  ? 178.995 207.900 271.779 1.00 136.71 ? 72  ASP A OD1 1 
ATOM   427   O  OD2 . ASP A 1 72  ? 179.802 208.583 269.856 1.00 136.09 ? 72  ASP A OD2 1 
ATOM   428   N  N   . LEU A 1 73  ? 176.456 206.264 272.829 1.00 135.81 ? 73  LEU A N   1 
ATOM   429   C  CA  . LEU A 1 73  ? 176.439 205.398 273.995 1.00 136.07 ? 73  LEU A CA  1 
ATOM   430   C  C   . LEU A 1 73  ? 175.159 205.504 274.809 1.00 138.44 ? 73  LEU A C   1 
ATOM   431   O  O   . LEU A 1 73  ? 175.068 204.869 275.865 1.00 139.29 ? 73  LEU A O   1 
ATOM   432   C  CB  . LEU A 1 73  ? 177.643 205.702 274.902 1.00 138.35 ? 73  LEU A CB  1 
ATOM   433   C  CG  . LEU A 1 73  ? 178.194 204.547 275.740 1.00 137.12 ? 73  LEU A CG  1 
ATOM   434   C  CD1 . LEU A 1 73  ? 178.538 203.357 274.857 1.00 132.36 ? 73  LEU A CD1 1 
ATOM   435   C  CD2 . LEU A 1 73  ? 179.406 205.002 276.537 1.00 131.33 ? 73  LEU A CD2 1 
ATOM   436   N  N   . ARG A 1 74  ? 174.168 206.269 274.350 1.00 139.27 ? 74  ARG A N   1 
ATOM   437   C  CA  . ARG A 1 74  ? 172.948 206.466 275.134 1.00 142.47 ? 74  ARG A CA  1 
ATOM   438   C  C   . ARG A 1 74  ? 172.260 205.162 275.521 1.00 145.21 ? 74  ARG A C   1 
ATOM   439   O  O   . ARG A 1 74  ? 171.899 205.013 276.700 1.00 145.03 ? 74  ARG A O   1 
ATOM   440   C  CB  . ARG A 1 74  ? 171.980 207.383 274.371 1.00 141.36 ? 74  ARG A CB  1 
ATOM   441   C  CG  . ARG A 1 74  ? 172.534 208.757 274.054 1.00 137.20 ? 74  ARG A CG  1 
ATOM   442   C  CD  . ARG A 1 74  ? 172.805 209.564 275.306 1.00 137.22 ? 74  ARG A CD  1 
ATOM   443   N  NE  . ARG A 1 74  ? 171.684 210.429 275.645 1.00 134.14 ? 74  ARG A NE  1 
ATOM   444   C  CZ  . ARG A 1 74  ? 171.596 211.704 275.296 1.00 133.86 ? 74  ARG A CZ  1 
ATOM   445   N  NH1 . ARG A 1 74  ? 172.552 212.296 274.599 1.00 135.75 ? 74  ARG A NH1 1 
ATOM   446   N  NH2 . ARG A 1 74  ? 170.523 212.403 275.652 1.00 132.74 ? 74  ARG A NH2 1 
ATOM   447   N  N   . PRO A 1 75  ? 172.044 204.195 274.621 1.00 148.95 ? 75  PRO A N   1 
ATOM   448   C  CA  . PRO A 1 75  ? 171.448 202.923 275.062 1.00 151.64 ? 75  PRO A CA  1 
ATOM   449   C  C   . PRO A 1 75  ? 172.324 202.147 276.028 1.00 148.96 ? 75  PRO A C   1 
ATOM   450   O  O   . PRO A 1 75  ? 171.807 201.291 276.756 1.00 147.48 ? 75  PRO A O   1 
ATOM   451   C  CB  . PRO A 1 75  ? 171.245 202.151 273.750 1.00 152.04 ? 75  PRO A CB  1 
ATOM   452   C  CG  . PRO A 1 75  ? 171.275 203.187 272.681 1.00 151.05 ? 75  PRO A CG  1 
ATOM   453   C  CD  . PRO A 1 75  ? 172.250 204.208 273.162 1.00 147.95 ? 75  PRO A CD  1 
ATOM   454   N  N   . ALA A 1 76  ? 173.628 202.418 276.064 1.00 145.86 ? 76  ALA A N   1 
ATOM   455   C  CA  . ALA A 1 76  ? 174.566 201.652 276.875 1.00 142.13 ? 76  ALA A CA  1 
ATOM   456   C  C   . ALA A 1 76  ? 175.178 202.500 277.983 1.00 137.34 ? 76  ALA A C   1 
ATOM   457   O  O   . ALA A 1 76  ? 176.311 202.262 278.402 1.00 134.11 ? 76  ALA A O   1 
ATOM   458   C  CB  . ALA A 1 76  ? 175.663 201.048 276.000 1.00 141.40 ? 76  ALA A CB  1 
ATOM   459   N  N   . HIS A 1 77  ? 174.446 203.492 278.460 1.00 136.54 ? 77  HIS A N   1 
ATOM   460   C  CA  . HIS A 1 77  ? 174.974 204.370 279.495 1.00 141.21 ? 77  HIS A CA  1 
ATOM   461   C  C   . HIS A 1 77  ? 174.909 203.783 280.904 1.00 145.39 ? 77  HIS A C   1 
ATOM   462   O  O   . HIS A 1 77  ? 175.956 203.603 281.536 1.00 148.59 ? 77  HIS A O   1 
ATOM   463   C  CB  . HIS A 1 77  ? 174.248 205.717 279.464 1.00 141.88 ? 77  HIS A CB  1 
ATOM   464   C  CG  . HIS A 1 77  ? 174.404 206.511 280.722 1.00 144.80 ? 77  HIS A CG  1 
ATOM   465   N  ND1 . HIS A 1 77  ? 175.636 206.841 281.246 1.00 145.87 ? 77  HIS A ND1 1 
ATOM   466   C  CD2 . HIS A 1 77  ? 173.484 207.032 281.567 1.00 143.27 ? 77  HIS A CD2 1 
ATOM   467   C  CE1 . HIS A 1 77  ? 175.468 207.534 282.358 1.00 141.19 ? 77  HIS A CE1 1 
ATOM   468   N  NE2 . HIS A 1 77  ? 174.172 207.665 282.575 1.00 143.29 ? 77  HIS A NE2 1 
ATOM   469   N  N   . PRO A 1 78  ? 173.723 203.465 281.439 1.00 143.44 ? 78  PRO A N   1 
ATOM   470   C  CA  . PRO A 1 78  ? 173.605 203.350 282.899 1.00 143.94 ? 78  PRO A CA  1 
ATOM   471   C  C   . PRO A 1 78  ? 174.112 202.043 283.484 1.00 144.32 ? 78  PRO A C   1 
ATOM   472   O  O   . PRO A 1 78  ? 174.435 202.012 284.682 1.00 145.49 ? 78  PRO A O   1 
ATOM   473   C  CB  . PRO A 1 78  ? 172.099 203.506 283.130 1.00 141.45 ? 78  PRO A CB  1 
ATOM   474   C  CG  . PRO A 1 78  ? 171.501 202.872 281.932 1.00 139.08 ? 78  PRO A CG  1 
ATOM   475   C  CD  . PRO A 1 78  ? 172.455 203.103 280.776 1.00 139.96 ? 78  PRO A CD  1 
ATOM   476   N  N   . GLU A 1 79  ? 174.215 200.982 282.683 1.00 142.60 ? 79  GLU A N   1 
ATOM   477   C  CA  . GLU A 1 79  ? 174.514 199.665 283.230 1.00 145.50 ? 79  GLU A CA  1 
ATOM   478   C  C   . GLU A 1 79  ? 175.848 199.643 283.957 1.00 148.91 ? 79  GLU A C   1 
ATOM   479   O  O   . GLU A 1 79  ? 175.987 198.948 284.968 1.00 149.34 ? 79  GLU A O   1 
ATOM   480   C  CB  . GLU A 1 79  ? 174.511 198.626 282.114 1.00 146.66 ? 79  GLU A CB  1 
ATOM   481   C  CG  . GLU A 1 79  ? 175.624 198.831 281.109 1.00 146.72 ? 79  GLU A CG  1 
ATOM   482   C  CD  . GLU A 1 79  ? 175.227 199.763 279.996 1.00 144.05 ? 79  GLU A CD  1 
ATOM   483   O  OE1 . GLU A 1 79  ? 174.667 200.839 280.294 1.00 139.92 ? 79  GLU A OE1 1 
ATOM   484   O  OE2 . GLU A 1 79  ? 175.480 199.418 278.826 1.00 146.91 ? 79  GLU A OE2 1 
ATOM   485   N  N   . TYR A 1 80  ? 176.834 200.397 283.470 1.00 150.97 ? 80  TYR A N   1 
ATOM   486   C  CA  . TYR A 1 80  ? 178.125 200.435 284.143 1.00 154.51 ? 80  TYR A CA  1 
ATOM   487   C  C   . TYR A 1 80  ? 177.994 201.034 285.535 1.00 154.27 ? 80  TYR A C   1 
ATOM   488   O  O   . TYR A 1 80  ? 178.660 200.592 286.478 1.00 152.34 ? 80  TYR A O   1 
ATOM   489   C  CB  . TYR A 1 80  ? 179.129 201.223 283.303 1.00 151.62 ? 80  TYR A CB  1 
ATOM   490   C  CG  . TYR A 1 80  ? 179.284 200.690 281.898 1.00 150.19 ? 80  TYR A CG  1 
ATOM   491   C  CD1 . TYR A 1 80  ? 180.141 199.631 281.628 1.00 151.49 ? 80  TYR A CD1 1 
ATOM   492   C  CD2 . TYR A 1 80  ? 178.570 201.241 280.843 1.00 147.09 ? 80  TYR A CD2 1 
ATOM   493   C  CE1 . TYR A 1 80  ? 180.286 199.139 280.346 1.00 153.10 ? 80  TYR A CE1 1 
ATOM   494   C  CE2 . TYR A 1 80  ? 178.709 200.756 279.558 1.00 147.17 ? 80  TYR A CE2 1 
ATOM   495   C  CZ  . TYR A 1 80  ? 179.567 199.705 279.315 1.00 150.99 ? 80  TYR A CZ  1 
ATOM   496   O  OH  . TYR A 1 80  ? 179.708 199.218 278.036 1.00 149.85 ? 80  TYR A OH  1 
ATOM   497   N  N   . ILE A 1 81  ? 177.125 202.033 285.688 1.00 155.60 ? 81  ILE A N   1 
ATOM   498   C  CA  . ILE A 1 81  ? 177.008 202.695 286.980 1.00 154.32 ? 81  ILE A CA  1 
ATOM   499   C  C   . ILE A 1 81  ? 176.184 201.842 287.944 1.00 152.09 ? 81  ILE A C   1 
ATOM   500   O  O   . ILE A 1 81  ? 176.497 201.767 289.136 1.00 151.57 ? 81  ILE A O   1 
ATOM   501   C  CB  . ILE A 1 81  ? 176.426 204.106 286.803 1.00 153.95 ? 81  ILE A CB  1 
ATOM   502   C  CG1 . ILE A 1 81  ? 177.198 204.865 285.725 1.00 146.39 ? 81  ILE A CG1 1 
ATOM   503   C  CG2 . ILE A 1 81  ? 176.584 204.883 288.091 1.00 152.26 ? 81  ILE A CG2 1 
ATOM   504   C  CD1 . ILE A 1 81  ? 176.644 206.241 285.441 1.00 139.05 ? 81  ILE A CD1 1 
ATOM   505   N  N   . ARG A 1 82  ? 175.122 201.188 287.453 1.00 149.25 ? 82  ARG A N   1 
ATOM   506   C  CA  . ARG A 1 82  ? 174.518 200.099 288.229 1.00 147.83 ? 82  ARG A CA  1 
ATOM   507   C  C   . ARG A 1 82  ? 175.549 199.073 288.680 1.00 149.68 ? 82  ARG A C   1 
ATOM   508   O  O   . ARG A 1 82  ? 175.539 198.651 289.842 1.00 151.90 ? 82  ARG A O   1 
ATOM   509   C  CB  . ARG A 1 82  ? 173.402 199.410 287.436 1.00 147.49 ? 82  ARG A CB  1 
ATOM   510   C  CG  . ARG A 1 82  ? 172.672 200.231 286.385 1.00 148.90 ? 82  ARG A CG  1 
ATOM   511   C  CD  . ARG A 1 82  ? 171.759 201.294 287.053 1.00 150.56 ? 82  ARG A CD  1 
ATOM   512   N  NE  . ARG A 1 82  ? 172.345 202.382 287.822 1.00 150.55 ? 82  ARG A NE  1 
ATOM   513   C  CZ  . ARG A 1 82  ? 173.093 203.359 287.335 1.00 148.37 ? 82  ARG A CZ  1 
ATOM   514   N  NH1 . ARG A 1 82  ? 173.411 203.411 286.058 1.00 145.35 ? 82  ARG A NH1 1 
ATOM   515   N  NH2 . ARG A 1 82  ? 173.511 204.321 288.152 1.00 149.99 ? 82  ARG A NH2 1 
ATOM   516   N  N   . HIS A 1 83  ? 176.431 198.641 287.780 1.00 149.90 ? 83  HIS A N   1 
ATOM   517   C  CA  . HIS A 1 83  ? 177.396 197.612 288.146 1.00 153.90 ? 83  HIS A CA  1 
ATOM   518   C  C   . HIS A 1 83  ? 178.355 198.112 289.218 1.00 153.77 ? 83  HIS A C   1 
ATOM   519   O  O   . HIS A 1 83  ? 178.679 197.382 290.162 1.00 154.05 ? 83  HIS A O   1 
ATOM   520   C  CB  . HIS A 1 83  ? 178.168 197.148 286.912 1.00 156.05 ? 83  HIS A CB  1 
ATOM   521   C  CG  . HIS A 1 83  ? 179.168 196.073 287.202 1.00 159.52 ? 83  HIS A CG  1 
ATOM   522   N  ND1 . HIS A 1 83  ? 178.801 194.777 287.491 1.00 159.43 ? 83  HIS A ND1 1 
ATOM   523   C  CD2 . HIS A 1 83  ? 180.520 196.103 287.256 1.00 158.78 ? 83  HIS A CD2 1 
ATOM   524   C  CE1 . HIS A 1 83  ? 179.885 194.053 287.707 1.00 157.43 ? 83  HIS A CE1 1 
ATOM   525   N  NE2 . HIS A 1 83  ? 180.942 194.834 287.570 1.00 157.52 ? 83  HIS A NE2 1 
ATOM   526   N  N   . ASN A 1 84  ? 178.824 199.352 289.087 1.00 152.74 ? 84  ASN A N   1 
ATOM   527   C  CA  . ASN A 1 84  ? 179.705 199.914 290.103 1.00 153.68 ? 84  ASN A CA  1 
ATOM   528   C  C   . ASN A 1 84  ? 178.980 200.071 291.434 1.00 154.23 ? 84  ASN A C   1 
ATOM   529   O  O   . ASN A 1 84  ? 179.566 199.830 292.496 1.00 154.09 ? 84  ASN A O   1 
ATOM   530   C  CB  . ASN A 1 84  ? 180.265 201.255 289.634 1.00 152.27 ? 84  ASN A CB  1 
ATOM   531   C  CG  . ASN A 1 84  ? 181.408 201.738 290.500 1.00 150.10 ? 84  ASN A CG  1 
ATOM   532   O  OD1 . ASN A 1 84  ? 181.194 202.371 291.534 1.00 151.63 ? 84  ASN A OD1 1 
ATOM   533   N  ND2 . ASN A 1 84  ? 182.632 201.435 290.086 1.00 144.91 ? 84  ASN A ND2 1 
ATOM   534   N  N   . ARG A 1 85  ? 177.708 200.477 291.397 1.00 153.55 ? 85  ARG A N   1 
ATOM   535   C  CA  . ARG A 1 85  ? 176.922 200.572 292.622 1.00 152.65 ? 85  ARG A CA  1 
ATOM   536   C  C   . ARG A 1 85  ? 176.808 199.215 293.297 1.00 155.45 ? 85  ARG A C   1 
ATOM   537   O  O   . ARG A 1 85  ? 176.929 199.107 294.523 1.00 155.90 ? 85  ARG A O   1 
ATOM   538   C  CB  . ARG A 1 85  ? 175.531 201.127 292.313 1.00 149.38 ? 85  ARG A CB  1 
ATOM   539   C  CG  . ARG A 1 85  ? 175.472 202.628 292.101 1.00 148.87 ? 85  ARG A CG  1 
ATOM   540   C  CD  . ARG A 1 85  ? 174.275 202.997 291.241 1.00 148.76 ? 85  ARG A CD  1 
ATOM   541   N  NE  . ARG A 1 85  ? 173.971 204.422 291.288 1.00 149.46 ? 85  ARG A NE  1 
ATOM   542   C  CZ  . ARG A 1 85  ? 173.176 204.987 292.185 1.00 147.36 ? 85  ARG A CZ  1 
ATOM   543   N  NH1 . ARG A 1 85  ? 172.606 204.279 293.146 1.00 149.50 ? 85  ARG A NH1 1 
ATOM   544   N  NH2 . ARG A 1 85  ? 172.946 206.295 292.117 1.00 142.40 ? 85  ARG A NH2 1 
ATOM   545   N  N   . GLU A 1 86  ? 176.568 198.167 292.508 1.00 157.90 ? 86  GLU A N   1 
ATOM   546   C  CA  . GLU A 1 86  ? 176.504 196.820 293.062 1.00 159.43 ? 86  GLU A CA  1 
ATOM   547   C  C   . GLU A 1 86  ? 177.843 196.411 293.661 1.00 159.66 ? 86  GLU A C   1 
ATOM   548   O  O   . GLU A 1 86  ? 177.892 195.817 294.745 1.00 159.40 ? 86  GLU A O   1 
ATOM   549   C  CB  . GLU A 1 86  ? 176.070 195.829 291.982 1.00 158.20 ? 86  GLU A CB  1 
ATOM   550   C  CG  . GLU A 1 86  ? 174.605 195.946 291.591 1.00 157.74 ? 86  GLU A CG  1 
ATOM   551   C  CD  . GLU A 1 86  ? 174.201 194.935 290.537 1.00 155.24 ? 86  GLU A CD  1 
ATOM   552   O  OE1 . GLU A 1 86  ? 174.994 194.011 290.262 1.00 152.77 ? 86  GLU A OE1 1 
ATOM   553   O  OE2 . GLU A 1 86  ? 173.089 195.065 289.982 1.00 154.34 ? 86  GLU A OE2 1 
ATOM   554   N  N   . GLY A 1 87  ? 178.940 196.722 292.970 1.00 158.69 ? 87  GLY A N   1 
ATOM   555   C  CA  . GLY A 1 87  ? 180.253 196.396 293.502 1.00 157.48 ? 87  GLY A CA  1 
ATOM   556   C  C   . GLY A 1 87  ? 180.590 197.180 294.757 1.00 158.20 ? 87  GLY A C   1 
ATOM   557   O  O   . GLY A 1 87  ? 181.108 196.621 295.728 1.00 158.58 ? 87  GLY A O   1 
ATOM   558   N  N   . GLY A 1 88  ? 180.302 198.479 294.757 1.00 157.82 ? 88  GLY A N   1 
ATOM   559   C  CA  . GLY A 1 88  ? 180.564 199.313 295.912 1.00 158.70 ? 88  GLY A CA  1 
ATOM   560   C  C   . GLY A 1 88  ? 182.011 199.699 296.121 1.00 159.47 ? 88  GLY A C   1 
ATOM   561   O  O   . GLY A 1 88  ? 182.347 200.212 297.195 1.00 155.37 ? 88  GLY A O   1 
ATOM   562   N  N   . LYS A 1 89  ? 182.878 199.470 295.138 1.00 160.97 ? 89  LYS A N   1 
ATOM   563   C  CA  . LYS A 1 89  ? 184.289 199.800 295.288 1.00 157.99 ? 89  LYS A CA  1 
ATOM   564   C  C   . LYS A 1 89  ? 184.491 201.311 295.280 1.00 160.36 ? 89  LYS A C   1 
ATOM   565   O  O   . LYS A 1 89  ? 183.882 202.027 294.480 1.00 159.38 ? 89  LYS A O   1 
ATOM   566   C  CB  . LYS A 1 89  ? 185.105 199.148 294.173 1.00 151.79 ? 89  LYS A CB  1 
ATOM   567   C  CG  . LYS A 1 89  ? 184.539 199.366 292.778 1.00 147.48 ? 89  LYS A CG  1 
ATOM   568   C  CD  . LYS A 1 89  ? 185.228 198.477 291.756 1.00 139.70 ? 89  LYS A CD  1 
ATOM   569   C  CE  . LYS A 1 89  ? 184.619 198.651 290.375 1.00 137.11 ? 89  LYS A CE  1 
ATOM   570   N  NZ  . LYS A 1 89  ? 185.078 197.597 289.429 1.00 134.09 ? 89  LYS A NZ  1 
ATOM   571   N  N   . ALA A 1 90  ? 185.349 201.795 296.182 1.00 162.08 ? 90  ALA A N   1 
ATOM   572   C  CA  . ALA A 1 90  ? 185.636 203.225 296.234 1.00 159.97 ? 90  ALA A CA  1 
ATOM   573   C  C   . ALA A 1 90  ? 186.536 203.654 295.081 1.00 156.88 ? 90  ALA A C   1 
ATOM   574   O  O   . ALA A 1 90  ? 186.320 204.712 294.478 1.00 152.28 ? 90  ALA A O   1 
ATOM   575   C  CB  . ALA A 1 90  ? 186.274 203.584 297.576 1.00 152.34 ? 90  ALA A CB  1 
ATOM   576   N  N   . ARG A 1 91  ? 187.547 202.849 294.761 1.00 155.74 ? 91  ARG A N   1 
ATOM   577   C  CA  . ARG A 1 91  ? 188.466 203.150 293.666 1.00 148.84 ? 91  ARG A CA  1 
ATOM   578   C  C   . ARG A 1 91  ? 187.809 202.720 292.363 1.00 144.63 ? 91  ARG A C   1 
ATOM   579   O  O   . ARG A 1 91  ? 187.800 201.537 292.017 1.00 141.80 ? 91  ARG A O   1 
ATOM   580   C  CB  . ARG A 1 91  ? 189.799 202.443 293.875 1.00 148.12 ? 91  ARG A CB  1 
ATOM   581   C  CG  . ARG A 1 91  ? 190.714 203.122 294.880 1.00 146.31 ? 91  ARG A CG  1 
ATOM   582   C  CD  . ARG A 1 91  ? 191.811 203.914 294.185 1.00 144.87 ? 91  ARG A CD  1 
ATOM   583   N  NE  . ARG A 1 91  ? 191.274 205.002 293.377 1.00 145.97 ? 91  ARG A NE  1 
ATOM   584   C  CZ  . ARG A 1 91  ? 190.868 206.167 293.861 1.00 145.71 ? 91  ARG A CZ  1 
ATOM   585   N  NH1 . ARG A 1 91  ? 190.925 206.436 295.155 1.00 143.81 ? 91  ARG A NH1 1 
ATOM   586   N  NH2 . ARG A 1 91  ? 190.393 207.087 293.026 1.00 143.91 ? 91  ARG A NH2 1 
ATOM   587   N  N   . VAL A 1 92  ? 187.260 203.686 291.629 1.00 144.25 ? 92  VAL A N   1 
ATOM   588   C  CA  . VAL A 1 92  ? 186.540 203.369 290.403 1.00 139.96 ? 92  VAL A CA  1 
ATOM   589   C  C   . VAL A 1 92  ? 187.524 202.879 289.351 1.00 135.14 ? 92  VAL A C   1 
ATOM   590   O  O   . VAL A 1 92  ? 188.550 203.519 289.086 1.00 134.24 ? 92  VAL A O   1 
ATOM   591   C  CB  . VAL A 1 92  ? 185.748 204.589 289.910 1.00 139.29 ? 92  VAL A CB  1 
ATOM   592   C  CG1 . VAL A 1 92  ? 184.494 204.777 290.748 1.00 141.87 ? 92  VAL A CG1 1 
ATOM   593   C  CG2 . VAL A 1 92  ? 186.611 205.841 289.958 1.00 138.28 ? 92  VAL A CG2 1 
ATOM   594   N  N   . GLU A 1 93  ? 187.224 201.725 288.759 1.00 134.08 ? 93  GLU A N   1 
ATOM   595   C  CA  . GLU A 1 93  ? 188.098 201.181 287.727 1.00 134.30 ? 93  GLU A CA  1 
ATOM   596   C  C   . GLU A 1 93  ? 187.929 201.934 286.414 1.00 135.21 ? 93  GLU A C   1 
ATOM   597   O  O   . GLU A 1 93  ? 188.890 202.092 285.653 1.00 135.23 ? 93  GLU A O   1 
ATOM   598   C  CB  . GLU A 1 93  ? 187.817 199.690 287.541 1.00 135.81 ? 93  GLU A CB  1 
ATOM   599   C  CG  . GLU A 1 93  ? 188.801 198.972 286.632 1.00 136.10 ? 93  GLU A CG  1 
ATOM   600   C  CD  . GLU A 1 93  ? 188.649 197.463 286.687 1.00 135.61 ? 93  GLU A CD  1 
ATOM   601   O  OE1 . GLU A 1 93  ? 187.634 196.986 287.238 1.00 136.87 ? 93  GLU A OE1 1 
ATOM   602   O  OE2 . GLU A 1 93  ? 189.544 196.754 286.180 1.00 133.79 ? 93  GLU A OE2 1 
ATOM   603   N  N   . GLY A 1 94  ? 186.716 202.408 286.134 1.00 136.96 ? 94  GLY A N   1 
ATOM   604   C  CA  . GLY A 1 94  ? 186.430 203.090 284.892 1.00 134.71 ? 94  GLY A CA  1 
ATOM   605   C  C   . GLY A 1 94  ? 186.928 204.520 284.878 1.00 129.06 ? 94  GLY A C   1 
ATOM   606   O  O   . GLY A 1 94  ? 187.515 205.024 285.834 1.00 129.23 ? 94  GLY A O   1 
ATOM   607   N  N   . MET A 1 95  ? 186.696 205.179 283.745 1.00 123.91 ? 95  MET A N   1 
ATOM   608   C  CA  . MET A 1 95  ? 187.128 206.549 283.488 1.00 123.58 ? 95  MET A CA  1 
ATOM   609   C  C   . MET A 1 95  ? 188.638 206.718 283.557 1.00 120.52 ? 95  MET A C   1 
ATOM   610   O  O   . MET A 1 95  ? 189.126 207.852 283.619 1.00 118.69 ? 95  MET A O   1 
ATOM   611   C  CB  . MET A 1 95  ? 186.457 207.545 284.443 1.00 128.05 ? 95  MET A CB  1 
ATOM   612   C  CG  . MET A 1 95  ? 184.958 207.386 284.548 1.00 131.68 ? 95  MET A CG  1 
ATOM   613   S  SD  . MET A 1 95  ? 184.167 207.754 282.974 1.00 135.31 ? 95  MET A SD  1 
ATOM   614   C  CE  . MET A 1 95  ? 183.293 209.257 283.396 1.00 123.82 ? 95  MET A CE  1 
ATOM   615   N  N   . SER A 1 96  ? 189.397 205.624 283.551 1.00 119.73 ? 96  SER A N   1 
ATOM   616   C  CA  . SER A 1 96  ? 190.845 205.742 283.525 1.00 115.90 ? 96  SER A CA  1 
ATOM   617   C  C   . SER A 1 96  ? 191.373 206.055 282.134 1.00 111.06 ? 96  SER A C   1 
ATOM   618   O  O   . SER A 1 96  ? 192.558 206.372 281.993 1.00 110.19 ? 96  SER A O   1 
ATOM   619   C  CB  . SER A 1 96  ? 191.483 204.453 284.040 1.00 117.01 ? 96  SER A CB  1 
ATOM   620   O  OG  . SER A 1 96  ? 190.929 204.078 285.289 1.00 120.77 ? 96  SER A OG  1 
ATOM   621   N  N   . ALA A 1 97  ? 190.528 205.977 281.115 1.00 109.43 ? 97  ALA A N   1 
ATOM   622   C  CA  . ALA A 1 97  ? 190.936 206.200 279.742 1.00 108.48 ? 97  ALA A CA  1 
ATOM   623   C  C   . ALA A 1 97  ? 190.468 207.572 279.276 1.00 109.44 ? 97  ALA A C   1 
ATOM   624   O  O   . ALA A 1 97  ? 189.886 208.352 280.030 1.00 108.54 ? 97  ALA A O   1 
ATOM   625   C  CB  . ALA A 1 97  ? 190.388 205.094 278.839 1.00 109.24 ? 97  ALA A CB  1 
ATOM   626   N  N   . GLU A 1 98  ? 190.736 207.868 278.010 1.00 110.16 ? 98  GLU A N   1 
ATOM   627   C  CA  . GLU A 1 98  ? 190.291 209.115 277.412 1.00 107.71 ? 98  GLU A CA  1 
ATOM   628   C  C   . GLU A 1 98  ? 188.825 209.010 277.026 1.00 107.45 ? 98  GLU A C   1 
ATOM   629   O  O   . GLU A 1 98  ? 188.338 207.933 276.673 1.00 103.23 ? 98  GLU A O   1 
ATOM   630   C  CB  . GLU A 1 98  ? 191.141 209.460 276.189 1.00 106.66 ? 98  GLU A CB  1 
ATOM   631   C  CG  . GLU A 1 98  ? 192.601 209.858 276.467 1.00 109.86 ? 98  GLU A CG  1 
ATOM   632   C  CD  . GLU A 1 98  ? 193.417 208.833 277.248 1.00 115.68 ? 98  GLU A CD  1 
ATOM   633   O  OE1 . GLU A 1 98  ? 192.950 207.692 277.448 1.00 115.89 ? 98  GLU A OE1 1 
ATOM   634   O  OE2 . GLU A 1 98  ? 194.543 209.178 277.664 1.00 117.10 ? 98  GLU A OE2 1 
ATOM   635   N  N   . LEU A 1 99  ? 188.113 210.128 277.112 1.00 111.49 ? 99  LEU A N   1 
ATOM   636   C  CA  . LEU A 1 99  ? 186.689 210.147 276.822 1.00 112.04 ? 99  LEU A CA  1 
ATOM   637   C  C   . LEU A 1 99  ? 186.396 211.124 275.695 1.00 110.19 ? 99  LEU A C   1 
ATOM   638   O  O   . LEU A 1 99  ? 187.081 212.134 275.530 1.00 109.63 ? 99  LEU A O   1 
ATOM   639   C  CB  . LEU A 1 99  ? 185.862 210.526 278.057 1.00 118.15 ? 99  LEU A CB  1 
ATOM   640   C  CG  . LEU A 1 99  ? 185.550 209.432 279.086 1.00 120.26 ? 99  LEU A CG  1 
ATOM   641   C  CD1 . LEU A 1 99  ? 184.826 208.265 278.436 1.00 116.62 ? 99  LEU A CD1 1 
ATOM   642   C  CD2 . LEU A 1 99  ? 186.790 208.958 279.827 1.00 116.92 ? 99  LEU A CD2 1 
ATOM   643   N  N   . GLN A 1 100 ? 185.362 210.815 274.930 1.00 109.22 ? 100 GLN A N   1 
ATOM   644   C  CA  . GLN A 1 100 ? 184.903 211.662 273.844 1.00 113.38 ? 100 GLN A CA  1 
ATOM   645   C  C   . GLN A 1 100 ? 183.601 212.344 274.244 1.00 120.41 ? 100 GLN A C   1 
ATOM   646   O  O   . GLN A 1 100 ? 182.629 211.677 274.612 1.00 120.79 ? 100 GLN A O   1 
ATOM   647   C  CB  . GLN A 1 100 ? 184.699 210.832 272.575 1.00 114.06 ? 100 GLN A CB  1 
ATOM   648   C  CG  . GLN A 1 100 ? 184.458 211.641 271.320 1.00 115.43 ? 100 GLN A CG  1 
ATOM   649   C  CD  . GLN A 1 100 ? 185.226 212.938 271.318 1.00 115.07 ? 100 GLN A CD  1 
ATOM   650   O  OE1 . GLN A 1 100 ? 186.454 212.949 271.252 1.00 108.63 ? 100 GLN A OE1 1 
ATOM   651   N  NE2 . GLN A 1 100 ? 184.505 214.046 271.415 1.00 122.29 ? 100 GLN A NE2 1 
ATOM   652   N  N   . LEU A 1 101 ? 183.583 213.672 274.174 1.00 123.01 ? 101 LEU A N   1 
ATOM   653   C  CA  . LEU A 1 101 ? 182.415 214.460 274.532 1.00 128.12 ? 101 LEU A CA  1 
ATOM   654   C  C   . LEU A 1 101 ? 181.915 215.203 273.303 1.00 129.04 ? 101 LEU A C   1 
ATOM   655   O  O   . LEU A 1 101 ? 182.707 215.631 272.460 1.00 127.61 ? 101 LEU A O   1 
ATOM   656   C  CB  . LEU A 1 101 ? 182.740 215.453 275.656 1.00 129.13 ? 101 LEU A CB  1 
ATOM   657   C  CG  . LEU A 1 101 ? 181.635 216.418 276.096 1.00 134.31 ? 101 LEU A CG  1 
ATOM   658   C  CD1 . LEU A 1 101 ? 181.524 216.438 277.611 1.00 137.44 ? 101 LEU A CD1 1 
ATOM   659   C  CD2 . LEU A 1 101 ? 181.879 217.819 275.557 1.00 131.16 ? 101 LEU A CD2 1 
ATOM   660   N  N   . GLU A 1 102 ? 180.597 215.335 273.194 1.00 133.29 ? 102 GLU A N   1 
ATOM   661   C  CA  . GLU A 1 102 ? 179.968 216.057 272.098 1.00 134.46 ? 102 GLU A CA  1 
ATOM   662   C  C   . GLU A 1 102 ? 179.437 217.387 272.613 1.00 138.56 ? 102 GLU A C   1 
ATOM   663   O  O   . GLU A 1 102 ? 178.722 217.427 273.620 1.00 139.93 ? 102 GLU A O   1 
ATOM   664   C  CB  . GLU A 1 102 ? 178.836 215.235 271.480 1.00 135.90 ? 102 GLU A CB  1 
ATOM   665   C  CG  . GLU A 1 102 ? 178.299 215.798 270.175 1.00 140.03 ? 102 GLU A CG  1 
ATOM   666   C  CD  . GLU A 1 102 ? 177.334 214.852 269.487 1.00 146.15 ? 102 GLU A CD  1 
ATOM   667   O  OE1 . GLU A 1 102 ? 176.855 213.906 270.147 1.00 144.04 ? 102 GLU A OE1 1 
ATOM   668   O  OE2 . GLU A 1 102 ? 177.055 215.054 268.287 1.00 149.32 ? 102 GLU A OE2 1 
ATOM   669   N  N   . LYS A 1 103 ? 179.785 218.469 271.923 1.00 140.56 ? 103 LYS A N   1 
ATOM   670   C  CA  . LYS A 1 103 ? 179.392 219.799 272.359 1.00 143.29 ? 103 LYS A CA  1 
ATOM   671   C  C   . LYS A 1 103 ? 177.932 220.071 271.999 1.00 144.80 ? 103 LYS A C   1 
ATOM   672   O  O   . LYS A 1 103 ? 177.250 219.253 271.376 1.00 143.76 ? 103 LYS A O   1 
ATOM   673   C  CB  . LYS A 1 103 ? 180.315 220.850 271.749 1.00 140.30 ? 103 LYS A CB  1 
ATOM   674   C  CG  . LYS A 1 103 ? 181.712 220.870 272.347 1.00 135.41 ? 103 LYS A CG  1 
ATOM   675   C  CD  . LYS A 1 103 ? 182.271 222.283 272.398 1.00 132.72 ? 103 LYS A CD  1 
ATOM   676   C  CE  . LYS A 1 103 ? 183.665 222.303 273.003 1.00 131.75 ? 103 LYS A CE  1 
ATOM   677   N  NZ  . LYS A 1 103 ? 184.111 223.686 273.329 1.00 134.96 ? 103 LYS A NZ  1 
ATOM   678   N  N   . LYS A 1 104 ? 177.447 221.246 272.406 1.00 145.80 ? 104 LYS A N   1 
ATOM   679   C  CA  . LYS A 1 104 ? 176.064 221.621 272.129 1.00 148.85 ? 104 LYS A CA  1 
ATOM   680   C  C   . LYS A 1 104 ? 175.804 221.759 270.635 1.00 148.38 ? 104 LYS A C   1 
ATOM   681   O  O   . LYS A 1 104 ? 174.734 221.367 270.155 1.00 147.57 ? 104 LYS A O   1 
ATOM   682   C  CB  . LYS A 1 104 ? 175.721 222.924 272.849 1.00 149.47 ? 104 LYS A CB  1 
ATOM   683   C  CG  . LYS A 1 104 ? 174.280 223.372 272.676 1.00 149.29 ? 104 LYS A CG  1 
ATOM   684   C  CD  . LYS A 1 104 ? 173.938 224.509 273.625 1.00 147.23 ? 104 LYS A CD  1 
ATOM   685   C  CE  . LYS A 1 104 ? 172.465 224.876 273.540 1.00 147.22 ? 104 LYS A CE  1 
ATOM   686   N  NZ  . LYS A 1 104 ? 172.123 226.009 274.443 1.00 147.10 ? 104 LYS A NZ  1 
ATOM   687   N  N   . ASP A 1 105 ? 176.761 222.305 269.889 1.00 148.05 ? 105 ASP A N   1 
ATOM   688   C  CA  . ASP A 1 105 ? 176.601 222.515 268.456 1.00 148.43 ? 105 ASP A CA  1 
ATOM   689   C  C   . ASP A 1 105 ? 176.840 221.253 267.638 1.00 146.83 ? 105 ASP A C   1 
ATOM   690   O  O   . ASP A 1 105 ? 176.682 221.291 266.413 1.00 144.75 ? 105 ASP A O   1 
ATOM   691   C  CB  . ASP A 1 105 ? 177.545 223.624 267.981 1.00 145.94 ? 105 ASP A CB  1 
ATOM   692   C  CG  . ASP A 1 105 ? 178.992 223.357 268.351 1.00 141.66 ? 105 ASP A CG  1 
ATOM   693   O  OD1 . ASP A 1 105 ? 179.253 222.373 269.074 1.00 141.72 ? 105 ASP A OD1 1 
ATOM   694   O  OD2 . ASP A 1 105 ? 179.869 224.134 267.918 1.00 138.12 ? 105 ASP A OD2 1 
ATOM   695   N  N   . GLY A 1 106 ? 177.213 220.145 268.276 1.00 144.76 ? 106 GLY A N   1 
ATOM   696   C  CA  . GLY A 1 106 ? 177.485 218.905 267.585 1.00 144.93 ? 106 GLY A CA  1 
ATOM   697   C  C   . GLY A 1 106 ? 178.954 218.576 267.422 1.00 143.80 ? 106 GLY A C   1 
ATOM   698   O  O   . GLY A 1 106 ? 179.277 217.464 266.988 1.00 142.47 ? 106 GLY A O   1 
ATOM   699   N  N   . SER A 1 107 ? 179.848 219.503 267.756 1.00 141.69 ? 107 SER A N   1 
ATOM   700   C  CA  . SER A 1 107 ? 181.272 219.241 267.643 1.00 135.94 ? 107 SER A CA  1 
ATOM   701   C  C   . SER A 1 107 ? 181.714 218.240 268.708 1.00 134.24 ? 107 SER A C   1 
ATOM   702   O  O   . SER A 1 107 ? 181.017 217.982 269.694 1.00 133.48 ? 107 SER A O   1 
ATOM   703   C  CB  . SER A 1 107 ? 182.067 220.540 267.761 1.00 133.18 ? 107 SER A CB  1 
ATOM   704   O  OG  . SER A 1 107 ? 181.882 221.138 269.030 1.00 132.44 ? 107 SER A OG  1 
ATOM   705   N  N   . LYS A 1 108 ? 182.893 217.663 268.492 1.00 132.52 ? 108 LYS A N   1 
ATOM   706   C  CA  . LYS A 1 108 ? 183.426 216.626 269.363 1.00 130.92 ? 108 LYS A CA  1 
ATOM   707   C  C   . LYS A 1 108 ? 184.784 217.055 269.900 1.00 130.97 ? 108 LYS A C   1 
ATOM   708   O  O   . LYS A 1 108 ? 185.637 217.521 269.139 1.00 130.90 ? 108 LYS A O   1 
ATOM   709   C  CB  . LYS A 1 108 ? 183.541 215.296 268.611 1.00 125.86 ? 108 LYS A CB  1 
ATOM   710   C  CG  . LYS A 1 108 ? 182.260 214.480 268.613 1.00 125.09 ? 108 LYS A CG  1 
ATOM   711   C  CD  . LYS A 1 108 ? 182.432 213.176 267.854 1.00 125.03 ? 108 LYS A CD  1 
ATOM   712   C  CE  . LYS A 1 108 ? 181.371 212.163 268.251 1.00 125.54 ? 108 LYS A CE  1 
ATOM   713   N  NZ  . LYS A 1 108 ? 181.555 210.861 267.553 1.00 126.87 ? 108 LYS A NZ  1 
ATOM   714   N  N   . ILE A 1 109 ? 184.977 216.895 271.211 1.00 130.13 ? 109 ILE A N   1 
ATOM   715   C  CA  . ILE A 1 109 ? 186.237 217.190 271.878 1.00 124.28 ? 109 ILE A CA  1 
ATOM   716   C  C   . ILE A 1 109 ? 186.596 216.013 272.774 1.00 117.17 ? 109 ILE A C   1 
ATOM   717   O  O   . ILE A 1 109 ? 185.781 215.129 273.036 1.00 117.16 ? 109 ILE A O   1 
ATOM   718   C  CB  . ILE A 1 109 ? 186.177 218.493 272.702 1.00 127.01 ? 109 ILE A CB  1 
ATOM   719   C  CG1 . ILE A 1 109 ? 184.985 218.463 273.659 1.00 127.85 ? 109 ILE A CG1 1 
ATOM   720   C  CG2 . ILE A 1 109 ? 186.101 219.703 271.784 1.00 127.36 ? 109 ILE A CG2 1 
ATOM   721   C  CD1 . ILE A 1 109 ? 185.196 219.275 274.917 1.00 127.46 ? 109 ILE A CD1 1 
ATOM   722   N  N   . TRP A 1 110 ? 187.836 216.004 273.238 1.00 113.01 ? 110 TRP A N   1 
ATOM   723   C  CA  . TRP A 1 110 ? 188.322 214.937 274.097 1.00 112.55 ? 110 TRP A CA  1 
ATOM   724   C  C   . TRP A 1 110 ? 188.507 215.459 275.514 1.00 115.57 ? 110 TRP A C   1 
ATOM   725   O  O   . TRP A 1 110 ? 189.075 216.536 275.721 1.00 108.96 ? 110 TRP A O   1 
ATOM   726   C  CB  . TRP A 1 110 ? 189.638 214.369 273.573 1.00 106.98 ? 110 TRP A CB  1 
ATOM   727   C  CG  . TRP A 1 110 ? 189.467 213.463 272.409 1.00 97.21  ? 110 TRP A CG  1 
ATOM   728   C  CD1 . TRP A 1 110 ? 189.481 213.810 271.095 1.00 96.38  ? 110 TRP A CD1 1 
ATOM   729   C  CD2 . TRP A 1 110 ? 189.235 212.055 272.450 1.00 94.64  ? 110 TRP A CD2 1 
ATOM   730   N  NE1 . TRP A 1 110 ? 189.287 212.703 270.312 1.00 93.07  ? 110 TRP A NE1 1 
ATOM   731   C  CE2 . TRP A 1 110 ? 189.132 211.612 271.122 1.00 92.05  ? 110 TRP A CE2 1 
ATOM   732   C  CE3 . TRP A 1 110 ? 189.115 211.125 273.482 1.00 99.49  ? 110 TRP A CE3 1 
ATOM   733   C  CZ2 . TRP A 1 110 ? 188.908 210.281 270.798 1.00 96.15  ? 110 TRP A CZ2 1 
ATOM   734   C  CZ3 . TRP A 1 110 ? 188.893 209.806 273.160 1.00 101.68 ? 110 TRP A CZ3 1 
ATOM   735   C  CH2 . TRP A 1 110 ? 188.792 209.394 271.829 1.00 99.93  ? 110 TRP A CH2 1 
ATOM   736   N  N   . THR A 1 111 ? 188.021 214.692 276.487 1.00 119.34 ? 111 THR A N   1 
ATOM   737   C  CA  . THR A 1 111 ? 188.054 215.097 277.884 1.00 118.49 ? 111 THR A CA  1 
ATOM   738   C  C   . THR A 1 111 ? 188.523 213.937 278.751 1.00 115.54 ? 111 THR A C   1 
ATOM   739   O  O   . THR A 1 111 ? 188.411 212.763 278.381 1.00 114.57 ? 111 THR A O   1 
ATOM   740   C  CB  . THR A 1 111 ? 186.680 215.584 278.369 1.00 121.51 ? 111 THR A CB  1 
ATOM   741   O  OG1 . THR A 1 111 ? 185.689 214.591 278.079 1.00 120.77 ? 111 THR A OG1 1 
ATOM   742   C  CG2 . THR A 1 111 ? 186.300 216.889 277.686 1.00 121.21 ? 111 THR A CG2 1 
ATOM   743   N  N   . ARG A 1 112 ? 189.058 214.293 279.918 1.00 109.03 ? 112 ARG A N   1 
ATOM   744   C  CA  . ARG A 1 112 ? 189.506 213.346 280.927 1.00 104.38 ? 112 ARG A CA  1 
ATOM   745   C  C   . ARG A 1 112 ? 188.635 213.497 282.163 1.00 101.79 ? 112 ARG A C   1 
ATOM   746   O  O   . ARG A 1 112 ? 188.217 214.607 282.504 1.00 102.64 ? 112 ARG A O   1 
ATOM   747   C  CB  . ARG A 1 112 ? 190.969 213.579 281.289 1.00 99.77  ? 112 ARG A CB  1 
ATOM   748   C  CG  . ARG A 1 112 ? 191.563 212.494 282.146 1.00 100.41 ? 112 ARG A CG  1 
ATOM   749   C  CD  . ARG A 1 112 ? 191.859 211.274 281.306 1.00 104.60 ? 112 ARG A CD  1 
ATOM   750   N  NE  . ARG A 1 112 ? 193.120 211.412 280.592 1.00 103.45 ? 112 ARG A NE  1 
ATOM   751   C  CZ  . ARG A 1 112 ? 194.304 211.088 281.092 1.00 102.94 ? 112 ARG A CZ  1 
ATOM   752   N  NH1 . ARG A 1 112 ? 194.426 210.593 282.312 1.00 105.57 ? 112 ARG A NH1 1 
ATOM   753   N  NH2 . ARG A 1 112 ? 195.392 211.264 280.349 1.00 103.37 ? 112 ARG A NH2 1 
ATOM   754   N  N   . PHE A 1 113 ? 188.368 212.384 282.833 1.00 103.07 ? 113 PHE A N   1 
ATOM   755   C  CA  . PHE A 1 113 ? 187.419 212.358 283.933 1.00 107.09 ? 113 PHE A CA  1 
ATOM   756   C  C   . PHE A 1 113 ? 188.079 211.813 285.188 1.00 106.04 ? 113 PHE A C   1 
ATOM   757   O  O   . PHE A 1 113 ? 188.922 210.915 285.123 1.00 104.88 ? 113 PHE A O   1 
ATOM   758   C  CB  . PHE A 1 113 ? 186.200 211.502 283.584 1.00 116.57 ? 113 PHE A CB  1 
ATOM   759   C  CG  . PHE A 1 113 ? 185.200 212.197 282.707 1.00 123.25 ? 113 PHE A CG  1 
ATOM   760   C  CD1 . PHE A 1 113 ? 185.450 212.367 281.355 1.00 122.89 ? 113 PHE A CD1 1 
ATOM   761   C  CD2 . PHE A 1 113 ? 184.012 212.680 283.229 1.00 126.91 ? 113 PHE A CD2 1 
ATOM   762   C  CE1 . PHE A 1 113 ? 184.534 213.002 280.540 1.00 123.70 ? 113 PHE A CE1 1 
ATOM   763   C  CE2 . PHE A 1 113 ? 183.091 213.316 282.418 1.00 130.11 ? 113 PHE A CE2 1 
ATOM   764   C  CZ  . PHE A 1 113 ? 183.353 213.478 281.072 1.00 128.05 ? 113 PHE A CZ  1 
ATOM   765   N  N   . ALA A 1 114 ? 187.698 212.380 286.326 1.00 109.78 ? 114 ALA A N   1 
ATOM   766   C  CA  . ALA A 1 114 ? 188.082 211.898 287.644 1.00 113.67 ? 114 ALA A CA  1 
ATOM   767   C  C   . ALA A 1 114 ? 186.819 211.748 288.474 1.00 113.44 ? 114 ALA A C   1 
ATOM   768   O  O   . ALA A 1 114 ? 186.071 212.712 288.652 1.00 112.40 ? 114 ALA A O   1 
ATOM   769   C  CB  . ALA A 1 114 ? 189.062 212.855 288.324 1.00 118.68 ? 114 ALA A CB  1 
ATOM   770   N  N   . LEU A 1 115 ? 186.588 210.549 288.984 1.00 117.70 ? 115 LEU A N   1 
ATOM   771   C  CA  . LEU A 1 115 ? 185.304 210.192 289.559 1.00 125.75 ? 115 LEU A CA  1 
ATOM   772   C  C   . LEU A 1 115 ? 185.432 210.001 291.062 1.00 127.35 ? 115 LEU A C   1 
ATOM   773   O  O   . LEU A 1 115 ? 186.533 209.901 291.608 1.00 128.06 ? 115 LEU A O   1 
ATOM   774   C  CB  . LEU A 1 115 ? 184.751 208.914 288.915 1.00 132.83 ? 115 LEU A CB  1 
ATOM   775   C  CG  . LEU A 1 115 ? 183.233 208.739 288.878 1.00 132.55 ? 115 LEU A CG  1 
ATOM   776   C  CD1 . LEU A 1 115 ? 182.586 209.833 288.045 1.00 128.08 ? 115 LEU A CD1 1 
ATOM   777   C  CD2 . LEU A 1 115 ? 182.881 207.366 288.334 1.00 130.94 ? 115 LEU A CD2 1 
ATOM   778   N  N   . SER A 1 116 ? 184.282 209.996 291.728 1.00 128.48 ? 116 SER A N   1 
ATOM   779   C  CA  . SER A 1 116 ? 184.227 209.684 293.152 1.00 130.56 ? 116 SER A CA  1 
ATOM   780   C  C   . SER A 1 116 ? 182.830 209.196 293.495 1.00 131.67 ? 116 SER A C   1 
ATOM   781   O  O   . SER A 1 116 ? 181.840 209.802 293.074 1.00 132.09 ? 116 SER A O   1 
ATOM   782   C  CB  . SER A 1 116 ? 184.596 210.904 293.995 1.00 134.70 ? 116 SER A CB  1 
ATOM   783   O  OG  . SER A 1 116 ? 185.999 211.090 294.016 1.00 137.24 ? 116 SER A OG  1 
ATOM   784   N  N   . LYS A 1 117 ? 182.753 208.110 294.255 1.00 134.84 ? 117 LYS A N   1 
ATOM   785   C  CA  . LYS A 1 117 ? 181.484 207.587 294.738 1.00 141.57 ? 117 LYS A CA  1 
ATOM   786   C  C   . LYS A 1 117 ? 181.333 207.931 296.213 1.00 143.90 ? 117 LYS A C   1 
ATOM   787   O  O   . LYS A 1 117 ? 182.236 207.666 297.012 1.00 143.58 ? 117 LYS A O   1 
ATOM   788   C  CB  . LYS A 1 117 ? 181.412 206.074 294.530 1.00 146.40 ? 117 LYS A CB  1 
ATOM   789   C  CG  . LYS A 1 117 ? 180.544 205.337 295.540 1.00 148.80 ? 117 LYS A CG  1 
ATOM   790   C  CD  . LYS A 1 117 ? 179.069 205.439 295.194 1.00 149.51 ? 117 LYS A CD  1 
ATOM   791   C  CE  . LYS A 1 117 ? 178.317 204.193 295.636 1.00 147.08 ? 117 LYS A CE  1 
ATOM   792   N  NZ  . LYS A 1 117 ? 178.354 204.013 297.114 1.00 144.20 ? 117 LYS A NZ  1 
ATOM   793   N  N   . VAL A 1 118 ? 180.199 208.527 296.569 1.00 144.91 ? 118 VAL A N   1 
ATOM   794   C  CA  . VAL A 1 118 ? 179.945 208.990 297.926 1.00 148.84 ? 118 VAL A CA  1 
ATOM   795   C  C   . VAL A 1 118 ? 178.714 208.273 298.458 1.00 150.70 ? 118 VAL A C   1 
ATOM   796   O  O   . VAL A 1 118 ? 177.674 208.240 297.793 1.00 147.83 ? 118 VAL A O   1 
ATOM   797   C  CB  . VAL A 1 118 ? 179.747 210.516 297.975 1.00 149.07 ? 118 VAL A CB  1 
ATOM   798   C  CG1 . VAL A 1 118 ? 179.622 210.989 299.416 1.00 148.70 ? 118 VAL A CG1 1 
ATOM   799   C  CG2 . VAL A 1 118 ? 180.891 211.223 297.269 1.00 145.51 ? 118 VAL A CG2 1 
ATOM   800   N  N   . SER A 1 119 ? 178.835 207.702 299.651 1.00 155.72 ? 119 SER A N   1 
ATOM   801   C  CA  . SER A 1 119 ? 177.713 207.091 300.359 1.00 158.06 ? 119 SER A CA  1 
ATOM   802   C  C   . SER A 1 119 ? 177.435 207.959 301.580 1.00 161.62 ? 119 SER A C   1 
ATOM   803   O  O   . SER A 1 119 ? 177.996 207.729 302.656 1.00 162.04 ? 119 SER A O   1 
ATOM   804   C  CB  . SER A 1 119 ? 178.020 205.648 300.749 1.00 155.93 ? 119 SER A CB  1 
ATOM   805   O  OG  . SER A 1 119 ? 176.897 205.037 301.362 1.00 151.83 ? 119 SER A OG  1 
ATOM   806   N  N   . ALA A 1 120 ? 176.569 208.955 301.412 1.00 163.51 ? 120 ALA A N   1 
ATOM   807   C  CA  . ALA A 1 120 ? 176.325 209.924 302.469 1.00 164.03 ? 120 ALA A CA  1 
ATOM   808   C  C   . ALA A 1 120 ? 174.836 210.219 302.559 1.00 164.88 ? 120 ALA A C   1 
ATOM   809   O  O   . ALA A 1 120 ? 174.115 210.156 301.559 1.00 162.17 ? 120 ALA A O   1 
ATOM   810   C  CB  . ALA A 1 120 ? 177.108 211.221 302.235 1.00 158.85 ? 120 ALA A CB  1 
ATOM   811   N  N   . GLU A 1 121 ? 174.393 210.557 303.773 1.00 167.58 ? 121 GLU A N   1 
ATOM   812   C  CA  . GLU A 1 121 ? 172.983 210.829 304.062 1.00 168.62 ? 121 GLU A CA  1 
ATOM   813   C  C   . GLU A 1 121 ? 172.097 209.654 303.657 1.00 166.80 ? 121 GLU A C   1 
ATOM   814   O  O   . GLU A 1 121 ? 170.953 209.836 303.233 1.00 166.55 ? 121 GLU A O   1 
ATOM   815   C  CB  . GLU A 1 121 ? 172.513 212.121 303.386 1.00 168.16 ? 121 GLU A CB  1 
ATOM   816   C  CG  . GLU A 1 121 ? 173.532 213.252 303.407 1.00 167.42 ? 121 GLU A CG  1 
ATOM   817   C  CD  . GLU A 1 121 ? 173.884 213.696 304.814 1.00 164.85 ? 121 GLU A CD  1 
ATOM   818   O  OE1 . GLU A 1 121 ? 172.983 213.706 305.679 1.00 164.14 ? 121 GLU A OE1 1 
ATOM   819   O  OE2 . GLU A 1 121 ? 175.061 214.037 305.054 1.00 160.47 ? 121 GLU A OE2 1 
ATOM   820   N  N   . GLY A 1 122 ? 172.624 208.439 303.790 1.00 165.20 ? 122 GLY A N   1 
ATOM   821   C  CA  . GLY A 1 122 ? 171.891 207.261 303.373 1.00 163.54 ? 122 GLY A CA  1 
ATOM   822   C  C   . GLY A 1 122 ? 171.622 207.187 301.890 1.00 161.61 ? 122 GLY A C   1 
ATOM   823   O  O   . GLY A 1 122 ? 170.677 206.511 301.474 1.00 159.22 ? 122 GLY A O   1 
ATOM   824   N  N   . LYS A 1 123 ? 172.427 207.865 301.075 1.00 161.29 ? 123 LYS A N   1 
ATOM   825   C  CA  . LYS A 1 123 ? 172.202 207.942 299.641 1.00 158.99 ? 123 LYS A CA  1 
ATOM   826   C  C   . LYS A 1 123 ? 173.533 207.843 298.911 1.00 156.03 ? 123 LYS A C   1 
ATOM   827   O  O   . LYS A 1 123 ? 174.609 207.969 299.502 1.00 156.00 ? 123 LYS A O   1 
ATOM   828   C  CB  . LYS A 1 123 ? 171.472 209.234 299.253 1.00 158.92 ? 123 LYS A CB  1 
ATOM   829   C  CG  . LYS A 1 123 ? 169.996 209.253 299.621 1.00 156.67 ? 123 LYS A CG  1 
ATOM   830   C  CD  . LYS A 1 123 ? 169.314 210.507 299.099 1.00 150.07 ? 123 LYS A CD  1 
ATOM   831   C  CE  . LYS A 1 123 ? 167.830 210.509 299.430 1.00 138.14 ? 123 LYS A CE  1 
ATOM   832   N  NZ  . LYS A 1 123 ? 167.151 211.738 298.935 1.00 128.59 ? 123 LYS A NZ  1 
ATOM   833   N  N   . VAL A 1 124 ? 173.440 207.616 297.603 1.00 153.03 ? 124 VAL A N   1 
ATOM   834   C  CA  . VAL A 1 124 ? 174.592 207.444 296.727 1.00 151.80 ? 124 VAL A CA  1 
ATOM   835   C  C   . VAL A 1 124 ? 174.704 208.668 295.830 1.00 149.15 ? 124 VAL A C   1 
ATOM   836   O  O   . VAL A 1 124 ? 173.728 209.066 295.184 1.00 148.53 ? 124 VAL A O   1 
ATOM   837   C  CB  . VAL A 1 124 ? 174.471 206.158 295.891 1.00 151.33 ? 124 VAL A CB  1 
ATOM   838   C  CG1 . VAL A 1 124 ? 175.440 206.186 294.721 1.00 151.09 ? 124 VAL A CG1 1 
ATOM   839   C  CG2 . VAL A 1 124 ? 174.710 204.935 296.761 1.00 150.58 ? 124 VAL A CG2 1 
ATOM   840   N  N   . TYR A 1 125 ? 175.892 209.263 295.797 1.00 148.48 ? 125 TYR A N   1 
ATOM   841   C  CA  . TYR A 1 125 ? 176.186 210.408 294.952 1.00 149.60 ? 125 TYR A CA  1 
ATOM   842   C  C   . TYR A 1 125 ? 177.441 210.119 294.140 1.00 147.11 ? 125 TYR A C   1 
ATOM   843   O  O   . TYR A 1 125 ? 178.311 209.346 294.550 1.00 144.55 ? 125 TYR A O   1 
ATOM   844   C  CB  . TYR A 1 125 ? 176.379 211.687 295.778 1.00 152.04 ? 125 TYR A CB  1 
ATOM   845   C  CG  . TYR A 1 125 ? 175.219 212.019 296.691 1.00 155.46 ? 125 TYR A CG  1 
ATOM   846   C  CD1 . TYR A 1 125 ? 175.084 211.403 297.929 1.00 156.28 ? 125 TYR A CD1 1 
ATOM   847   C  CD2 . TYR A 1 125 ? 174.261 212.953 296.317 1.00 155.15 ? 125 TYR A CD2 1 
ATOM   848   C  CE1 . TYR A 1 125 ? 174.026 211.705 298.766 1.00 158.82 ? 125 TYR A CE1 1 
ATOM   849   C  CE2 . TYR A 1 125 ? 173.200 213.261 297.147 1.00 156.44 ? 125 TYR A CE2 1 
ATOM   850   C  CZ  . TYR A 1 125 ? 173.087 212.634 298.370 1.00 159.50 ? 125 TYR A CZ  1 
ATOM   851   O  OH  . TYR A 1 125 ? 172.033 212.938 299.199 1.00 159.62 ? 125 TYR A OH  1 
ATOM   852   N  N   . TYR A 1 126 ? 177.527 210.746 292.973 1.00 143.75 ? 126 TYR A N   1 
ATOM   853   C  CA  . TYR A 1 126 ? 178.683 210.583 292.105 1.00 141.63 ? 126 TYR A CA  1 
ATOM   854   C  C   . TYR A 1 126 ? 179.234 211.949 291.739 1.00 137.60 ? 126 TYR A C   1 
ATOM   855   O  O   . TYR A 1 126 ? 178.507 212.797 291.213 1.00 138.18 ? 126 TYR A O   1 
ATOM   856   C  CB  . TYR A 1 126 ? 178.326 209.790 290.847 1.00 145.79 ? 126 TYR A CB  1 
ATOM   857   C  CG  . TYR A 1 126 ? 178.858 208.377 290.873 1.00 149.88 ? 126 TYR A CG  1 
ATOM   858   C  CD1 . TYR A 1 126 ? 180.211 208.129 291.063 1.00 147.49 ? 126 TYR A CD1 1 
ATOM   859   C  CD2 . TYR A 1 126 ? 178.007 207.291 290.731 1.00 153.30 ? 126 TYR A CD2 1 
ATOM   860   C  CE1 . TYR A 1 126 ? 180.703 206.840 291.096 1.00 148.66 ? 126 TYR A CE1 1 
ATOM   861   C  CE2 . TYR A 1 126 ? 178.490 205.998 290.764 1.00 152.82 ? 126 TYR A CE2 1 
ATOM   862   C  CZ  . TYR A 1 126 ? 179.838 205.779 290.946 1.00 151.05 ? 126 TYR A CZ  1 
ATOM   863   O  OH  . TYR A 1 126 ? 180.322 204.493 290.979 1.00 151.18 ? 126 TYR A OH  1 
ATOM   864   N  N   . LEU A 1 127 ? 180.518 212.153 292.016 1.00 134.19 ? 127 LEU A N   1 
ATOM   865   C  CA  . LEU A 1 127 ? 181.203 213.406 291.738 1.00 132.41 ? 127 LEU A CA  1 
ATOM   866   C  C   . LEU A 1 127 ? 182.144 213.207 290.561 1.00 126.71 ? 127 LEU A C   1 
ATOM   867   O  O   . LEU A 1 127 ? 182.920 212.248 290.540 1.00 125.80 ? 127 LEU A O   1 
ATOM   868   C  CB  . LEU A 1 127 ? 181.975 213.892 292.967 1.00 135.17 ? 127 LEU A CB  1 
ATOM   869   C  CG  . LEU A 1 127 ? 182.749 215.204 292.832 1.00 133.00 ? 127 LEU A CG  1 
ATOM   870   C  CD1 . LEU A 1 127 ? 181.845 216.392 293.121 1.00 132.92 ? 127 LEU A CD1 1 
ATOM   871   C  CD2 . LEU A 1 127 ? 183.949 215.207 293.765 1.00 131.14 ? 127 LEU A CD2 1 
ATOM   872   N  N   . ALA A 1 128 ? 182.061 214.104 289.586 1.00 121.70 ? 128 ALA A N   1 
ATOM   873   C  CA  . ALA A 1 128 ? 182.839 214.034 288.365 1.00 118.70 ? 128 ALA A CA  1 
ATOM   874   C  C   . ALA A 1 128 ? 183.632 215.318 288.187 1.00 116.18 ? 128 ALA A C   1 
ATOM   875   O  O   . ALA A 1 128 ? 183.123 216.419 288.430 1.00 117.38 ? 128 ALA A O   1 
ATOM   876   C  CB  . ALA A 1 128 ? 181.939 213.803 287.149 1.00 122.47 ? 128 ALA A CB  1 
ATOM   877   N  N   . LEU A 1 129 ? 184.882 215.158 287.766 1.00 111.40 ? 129 LEU A N   1 
ATOM   878   C  CA  . LEU A 1 129 ? 185.796 216.259 287.516 1.00 109.98 ? 129 LEU A CA  1 
ATOM   879   C  C   . LEU A 1 129 ? 186.334 216.101 286.107 1.00 103.52 ? 129 LEU A C   1 
ATOM   880   O  O   . LEU A 1 129 ? 186.879 215.052 285.767 1.00 104.50 ? 129 LEU A O   1 
ATOM   881   C  CB  . LEU A 1 129 ? 186.940 216.263 288.530 1.00 117.49 ? 129 LEU A CB  1 
ATOM   882   C  CG  . LEU A 1 129 ? 186.607 216.769 289.936 1.00 123.89 ? 129 LEU A CG  1 
ATOM   883   C  CD1 . LEU A 1 129 ? 185.671 217.966 289.877 1.00 125.86 ? 129 LEU A CD1 1 
ATOM   884   C  CD2 . LEU A 1 129 ? 186.013 215.658 290.785 1.00 126.47 ? 129 LEU A CD2 1 
ATOM   885   N  N   . VAL A 1 130 ? 186.185 217.137 285.296 1.00 100.70 ? 130 VAL A N   1 
ATOM   886   C  CA  . VAL A 1 130 ? 186.433 217.056 283.865 1.00 105.64 ? 130 VAL A CA  1 
ATOM   887   C  C   . VAL A 1 130 ? 187.566 218.003 283.514 1.00 102.94 ? 130 VAL A C   1 
ATOM   888   O  O   . VAL A 1 130 ? 187.505 219.199 283.826 1.00 108.61 ? 130 VAL A O   1 
ATOM   889   C  CB  . VAL A 1 130 ? 185.176 217.390 283.049 1.00 117.29 ? 130 VAL A CB  1 
ATOM   890   C  CG1 . VAL A 1 130 ? 185.439 217.196 281.564 1.00 115.35 ? 130 VAL A CG1 1 
ATOM   891   C  CG2 . VAL A 1 130 ? 184.001 216.542 283.512 1.00 122.50 ? 130 VAL A CG2 1 
ATOM   892   N  N   . ARG A 1 131 ? 188.586 217.471 282.850 1.00 97.27  ? 131 ARG A N   1 
ATOM   893   C  CA  . ARG A 1 131 ? 189.702 218.254 282.342 1.00 96.50  ? 131 ARG A CA  1 
ATOM   894   C  C   . ARG A 1 131 ? 189.716 218.194 280.822 1.00 98.55  ? 131 ARG A C   1 
ATOM   895   O  O   . ARG A 1 131 ? 189.427 217.147 280.237 1.00 100.05 ? 131 ARG A O   1 
ATOM   896   C  CB  . ARG A 1 131 ? 191.026 217.741 282.897 1.00 93.63  ? 131 ARG A CB  1 
ATOM   897   C  CG  . ARG A 1 131 ? 192.150 218.742 282.793 1.00 93.63  ? 131 ARG A CG  1 
ATOM   898   C  CD  . ARG A 1 131 ? 193.346 218.300 283.600 1.00 97.81  ? 131 ARG A CD  1 
ATOM   899   N  NE  . ARG A 1 131 ? 193.075 218.382 285.029 1.00 105.45 ? 131 ARG A NE  1 
ATOM   900   C  CZ  . ARG A 1 131 ? 192.819 217.337 285.801 1.00 108.85 ? 131 ARG A CZ  1 
ATOM   901   N  NH1 . ARG A 1 131 ? 192.779 216.110 285.311 1.00 109.18 ? 131 ARG A NH1 1 
ATOM   902   N  NH2 . ARG A 1 131 ? 192.595 217.529 287.098 1.00 110.21 ? 131 ARG A NH2 1 
ATOM   903   N  N   . ASP A 1 132 ? 190.045 219.315 280.187 1.00 93.79  ? 132 ASP A N   1 
ATOM   904   C  CA  . ASP A 1 132 ? 190.181 219.352 278.736 1.00 89.10  ? 132 ASP A CA  1 
ATOM   905   C  C   . ASP A 1 132 ? 191.609 218.995 278.358 1.00 87.58  ? 132 ASP A C   1 
ATOM   906   O  O   . ASP A 1 132 ? 192.544 219.753 278.633 1.00 87.63  ? 132 ASP A O   1 
ATOM   907   C  CB  . ASP A 1 132 ? 189.812 220.720 278.180 1.00 89.21  ? 132 ASP A CB  1 
ATOM   908   C  CG  . ASP A 1 132 ? 190.080 220.823 276.696 1.00 86.79  ? 132 ASP A CG  1 
ATOM   909   O  OD1 . ASP A 1 132 ? 190.194 221.956 276.188 1.00 89.43  ? 132 ASP A OD1 1 
ATOM   910   O  OD2 . ASP A 1 132 ? 190.184 219.767 276.038 1.00 83.15  ? 132 ASP A OD2 1 
ATOM   911   N  N   . ALA A 1 133 ? 191.775 217.848 277.709 1.00 90.03  ? 133 ALA A N   1 
ATOM   912   C  CA  . ALA A 1 133 ? 193.073 217.397 277.241 1.00 86.79  ? 133 ALA A CA  1 
ATOM   913   C  C   . ALA A 1 133 ? 193.285 217.697 275.768 1.00 78.87  ? 133 ALA A C   1 
ATOM   914   O  O   . ALA A 1 133 ? 194.116 217.048 275.123 1.00 75.32  ? 133 ALA A O   1 
ATOM   915   C  CB  . ALA A 1 133 ? 193.232 215.901 277.505 1.00 91.58  ? 133 ALA A CB  1 
ATOM   916   N  N   . SER A 1 134 ? 192.546 218.664 275.221 1.00 79.69  ? 134 SER A N   1 
ATOM   917   C  CA  . SER A 1 134 ? 192.698 218.985 273.807 1.00 82.41  ? 134 SER A CA  1 
ATOM   918   C  C   . SER A 1 134 ? 194.146 219.303 273.483 1.00 75.97  ? 134 SER A C   1 
ATOM   919   O  O   . SER A 1 134 ? 194.698 218.785 272.511 1.00 71.10  ? 134 SER A O   1 
ATOM   920   C  CB  . SER A 1 134 ? 191.797 220.157 273.428 1.00 87.42  ? 134 SER A CB  1 
ATOM   921   O  OG  . SER A 1 134 ? 192.056 221.280 274.251 1.00 91.42  ? 134 SER A OG  1 
ATOM   922   N  N   . VAL A 1 135 ? 194.788 220.122 274.311 1.00 77.29  ? 135 VAL A N   1 
ATOM   923   C  CA  . VAL A 1 135 ? 196.219 220.343 274.156 1.00 76.88  ? 135 VAL A CA  1 
ATOM   924   C  C   . VAL A 1 135 ? 196.978 219.045 274.385 1.00 72.17  ? 135 VAL A C   1 
ATOM   925   O  O   . VAL A 1 135 ? 197.939 218.740 273.675 1.00 68.21  ? 135 VAL A O   1 
ATOM   926   C  CB  . VAL A 1 135 ? 196.693 221.461 275.103 1.00 81.31  ? 135 VAL A CB  1 
ATOM   927   C  CG1 . VAL A 1 135 ? 196.133 221.252 276.501 1.00 85.22  ? 135 VAL A CG1 1 
ATOM   928   C  CG2 . VAL A 1 135 ? 198.211 221.524 275.133 1.00 76.18  ? 135 VAL A CG2 1 
ATOM   929   N  N   . GLU A 1 136 ? 196.550 218.252 275.367 1.00 72.74  ? 136 GLU A N   1 
ATOM   930   C  CA  . GLU A 1 136 ? 197.276 217.029 275.692 1.00 78.30  ? 136 GLU A CA  1 
ATOM   931   C  C   . GLU A 1 136 ? 197.244 216.039 274.535 1.00 77.62  ? 136 GLU A C   1 
ATOM   932   O  O   . GLU A 1 136 ? 198.293 215.582 274.065 1.00 76.36  ? 136 GLU A O   1 
ATOM   933   C  CB  . GLU A 1 136 ? 196.696 216.395 276.955 1.00 86.51  ? 136 GLU A CB  1 
ATOM   934   C  CG  . GLU A 1 136 ? 197.388 215.109 277.375 1.00 90.11  ? 136 GLU A CG  1 
ATOM   935   C  CD  . GLU A 1 136 ? 196.786 214.502 278.628 1.00 96.66  ? 136 GLU A CD  1 
ATOM   936   O  OE1 . GLU A 1 136 ? 195.853 215.106 279.197 1.00 101.26 ? 136 GLU A OE1 1 
ATOM   937   O  OE2 . GLU A 1 136 ? 197.244 213.416 279.041 1.00 98.32  ? 136 GLU A OE2 1 
ATOM   938   N  N   . MET A 1 137 ? 196.055 215.707 274.034 1.00 80.14  ? 137 MET A N   1 
ATOM   939   C  CA  . MET A 1 137 ? 196.046 214.759 272.931 1.00 80.18  ? 137 MET A CA  1 
ATOM   940   C  C   . MET A 1 137 ? 196.497 215.392 271.630 1.00 70.57  ? 137 MET A C   1 
ATOM   941   O  O   . MET A 1 137 ? 196.961 214.677 270.746 1.00 72.15  ? 137 MET A O   1 
ATOM   942   C  CB  . MET A 1 137 ? 194.674 214.117 272.731 1.00 87.32  ? 137 MET A CB  1 
ATOM   943   C  CG  . MET A 1 137 ? 194.566 212.744 273.381 1.00 92.46  ? 137 MET A CG  1 
ATOM   944   S  SD  . MET A 1 137 ? 192.893 212.093 273.369 1.00 112.28 ? 137 MET A SD  1 
ATOM   945   C  CE  . MET A 1 137 ? 192.509 212.341 271.637 1.00 98.67  ? 137 MET A CE  1 
ATOM   946   N  N   . ALA A 1 138 ? 196.365 216.706 271.481 1.00 66.76  ? 138 ALA A N   1 
ATOM   947   C  CA  . ALA A 1 138 ? 196.967 217.351 270.328 1.00 67.86  ? 138 ALA A CA  1 
ATOM   948   C  C   . ALA A 1 138 ? 198.467 217.151 270.353 1.00 66.55  ? 138 ALA A C   1 
ATOM   949   O  O   . ALA A 1 138 ? 199.087 216.874 269.322 1.00 67.85  ? 138 ALA A O   1 
ATOM   950   C  CB  . ALA A 1 138 ? 196.617 218.837 270.309 1.00 73.44  ? 138 ALA A CB  1 
ATOM   951   N  N   . GLN A 1 139 ? 199.058 217.253 271.540 1.00 63.60  ? 139 GLN A N   1 
ATOM   952   C  CA  . GLN A 1 139 ? 200.463 216.933 271.710 1.00 61.69  ? 139 GLN A CA  1 
ATOM   953   C  C   . GLN A 1 139 ? 200.719 215.470 271.385 1.00 67.24  ? 139 GLN A C   1 
ATOM   954   O  O   . GLN A 1 139 ? 201.745 215.127 270.794 1.00 65.02  ? 139 GLN A O   1 
ATOM   955   C  CB  . GLN A 1 139 ? 200.882 217.259 273.138 1.00 59.07  ? 139 GLN A CB  1 
ATOM   956   C  CG  . GLN A 1 139 ? 202.322 217.655 273.291 1.00 58.61  ? 139 GLN A CG  1 
ATOM   957   C  CD  . GLN A 1 139 ? 202.637 218.941 272.584 1.00 62.45  ? 139 GLN A CD  1 
ATOM   958   O  OE1 . GLN A 1 139 ? 203.078 218.936 271.438 1.00 64.20  ? 139 GLN A OE1 1 
ATOM   959   N  NE2 . GLN A 1 139 ? 202.415 220.058 273.259 1.00 65.82  ? 139 GLN A NE2 1 
ATOM   960   N  N   . LYS A 1 140 ? 199.783 214.594 271.755 1.00 71.11  ? 140 LYS A N   1 
ATOM   961   C  CA  . LYS A 1 140 ? 199.946 213.168 271.476 1.00 71.54  ? 140 LYS A CA  1 
ATOM   962   C  C   . LYS A 1 140 ? 200.000 212.889 269.977 1.00 70.24  ? 140 LYS A C   1 
ATOM   963   O  O   . LYS A 1 140 ? 200.930 212.239 269.484 1.00 70.21  ? 140 LYS A O   1 
ATOM   964   C  CB  . LYS A 1 140 ? 198.808 212.376 272.121 1.00 69.07  ? 140 LYS A CB  1 
ATOM   965   C  CG  . LYS A 1 140 ? 198.783 212.385 273.642 1.00 69.76  ? 140 LYS A CG  1 
ATOM   966   C  CD  . LYS A 1 140 ? 200.061 211.844 274.291 1.00 74.49  ? 140 LYS A CD  1 
ATOM   967   C  CE  . LYS A 1 140 ? 200.654 210.629 273.572 1.00 76.92  ? 140 LYS A CE  1 
ATOM   968   N  NZ  . LYS A 1 140 ? 199.639 209.587 273.251 1.00 74.53  ? 140 LYS A NZ  1 
ATOM   969   N  N   . GLU A 1 141 ? 199.001 213.364 269.236 1.00 72.68  ? 141 GLU A N   1 
ATOM   970   C  CA  . GLU A 1 141 ? 198.991 213.131 267.797 1.00 69.97  ? 141 GLU A CA  1 
ATOM   971   C  C   . GLU A 1 141 ? 200.128 213.872 267.125 1.00 64.56  ? 141 GLU A C   1 
ATOM   972   O  O   . GLU A 1 141 ? 200.638 213.428 266.094 1.00 67.77  ? 141 GLU A O   1 
ATOM   973   C  CB  . GLU A 1 141 ? 197.657 213.535 267.168 1.00 77.00  ? 141 GLU A CB  1 
ATOM   974   C  CG  . GLU A 1 141 ? 196.462 213.526 268.091 1.00 81.81  ? 141 GLU A CG  1 
ATOM   975   C  CD  . GLU A 1 141 ? 195.248 214.195 267.477 1.00 86.95  ? 141 GLU A CD  1 
ATOM   976   O  OE1 . GLU A 1 141 ? 195.208 214.340 266.237 1.00 89.25  ? 141 GLU A OE1 1 
ATOM   977   O  OE2 . GLU A 1 141 ? 194.333 214.577 268.237 1.00 87.68  ? 141 GLU A OE2 1 
ATOM   978   N  N   . GLN A 1 142 ? 200.538 215.009 267.682 1.00 62.00  ? 142 GLN A N   1 
ATOM   979   C  CA  . GLN A 1 142 ? 201.702 215.685 267.137 1.00 64.99  ? 142 GLN A CA  1 
ATOM   980   C  C   . GLN A 1 142 ? 202.942 214.831 267.326 1.00 59.67  ? 142 GLN A C   1 
ATOM   981   O  O   . GLN A 1 142 ? 203.791 214.742 266.433 1.00 59.36  ? 142 GLN A O   1 
ATOM   982   C  CB  . GLN A 1 142 ? 201.872 217.053 267.792 1.00 67.20  ? 142 GLN A CB  1 
ATOM   983   C  CG  . GLN A 1 142 ? 203.139 217.773 267.369 1.00 65.13  ? 142 GLN A CG  1 
ATOM   984   C  CD  . GLN A 1 142 ? 203.152 219.226 267.771 1.00 65.97  ? 142 GLN A CD  1 
ATOM   985   O  OE1 . GLN A 1 142 ? 204.185 219.886 267.707 1.00 63.78  ? 142 GLN A OE1 1 
ATOM   986   N  NE2 . GLN A 1 142 ? 202.003 219.733 268.195 1.00 66.15  ? 142 GLN A NE2 1 
ATOM   987   N  N   . THR A 1 143 ? 203.054 214.183 268.479 1.00 52.58  ? 143 THR A N   1 
ATOM   988   C  CA  . THR A 1 143 ? 204.173 213.290 268.718 1.00 51.60  ? 143 THR A CA  1 
ATOM   989   C  C   . THR A 1 143 ? 204.151 212.134 267.738 1.00 58.77  ? 143 THR A C   1 
ATOM   990   O  O   . THR A 1 143 ? 205.191 211.747 267.200 1.00 60.65  ? 143 THR A O   1 
ATOM   991   C  CB  . THR A 1 143 ? 204.126 212.779 270.149 1.00 56.86  ? 143 THR A CB  1 
ATOM   992   O  OG1 . THR A 1 143 ? 203.664 213.825 271.009 1.00 61.36  ? 143 THR A OG1 1 
ATOM   993   C  CG2 . THR A 1 143 ? 205.503 212.345 270.594 1.00 60.27  ? 143 THR A CG2 1 
ATOM   994   N  N   . ARG A 1 144 ? 202.968 211.575 267.490 1.00 66.64  ? 144 ARG A N   1 
ATOM   995   C  CA  . ARG A 1 144 ? 202.852 210.457 266.557 1.00 65.64  ? 144 ARG A CA  1 
ATOM   996   C  C   . ARG A 1 144 ? 203.222 210.881 265.141 1.00 58.43  ? 144 ARG A C   1 
ATOM   997   O  O   . ARG A 1 144 ? 203.971 210.185 264.446 1.00 56.07  ? 144 ARG A O   1 
ATOM   998   C  CB  . ARG A 1 144 ? 201.433 209.900 266.592 1.00 70.09  ? 144 ARG A CB  1 
ATOM   999   C  CG  . ARG A 1 144 ? 201.310 208.506 266.036 1.00 74.41  ? 144 ARG A CG  1 
ATOM   1000  C  CD  . ARG A 1 144 ? 199.862 208.091 265.969 1.00 77.04  ? 144 ARG A CD  1 
ATOM   1001  N  NE  . ARG A 1 144 ? 199.056 209.105 265.305 1.00 77.14  ? 144 ARG A NE  1 
ATOM   1002  C  CZ  . ARG A 1 144 ? 198.990 209.256 263.991 1.00 79.61  ? 144 ARG A CZ  1 
ATOM   1003  N  NH1 . ARG A 1 144 ? 199.684 208.486 263.171 1.00 78.56  ? 144 ARG A NH1 1 
ATOM   1004  N  NH2 . ARG A 1 144 ? 198.208 210.205 263.487 1.00 82.74  ? 144 ARG A NH2 1 
ATOM   1005  N  N   . GLN A 1 145 ? 202.696 212.024 264.696 1.00 58.12  ? 145 GLN A N   1 
ATOM   1006  C  CA  . GLN A 1 145 ? 203.010 212.521 263.365 1.00 55.63  ? 145 GLN A CA  1 
ATOM   1007  C  C   . GLN A 1 145 ? 204.490 212.802 263.234 1.00 50.26  ? 145 GLN A C   1 
ATOM   1008  O  O   . GLN A 1 145 ? 205.099 212.505 262.203 1.00 51.90  ? 145 GLN A O   1 
ATOM   1009  C  CB  . GLN A 1 145 ? 202.214 213.786 263.063 1.00 62.15  ? 145 GLN A CB  1 
ATOM   1010  C  CG  . GLN A 1 145 ? 200.922 213.553 262.317 1.00 67.57  ? 145 GLN A CG  1 
ATOM   1011  C  CD  . GLN A 1 145 ? 199.808 214.457 262.794 1.00 68.93  ? 145 GLN A CD  1 
ATOM   1012  O  OE1 . GLN A 1 145 ? 200.006 215.296 263.672 1.00 64.40  ? 145 GLN A OE1 1 
ATOM   1013  N  NE2 . GLN A 1 145 ? 198.625 214.292 262.217 1.00 72.71  ? 145 GLN A NE2 1 
ATOM   1014  N  N   . LEU A 1 146 ? 205.088 213.371 264.272 1.00 49.68  ? 146 LEU A N   1 
ATOM   1015  C  CA  . LEU A 1 146 ? 206.506 213.664 264.219 1.00 50.44  ? 146 LEU A CA  1 
ATOM   1016  C  C   . LEU A 1 146 ? 207.333 212.393 264.222 1.00 52.94  ? 146 LEU A C   1 
ATOM   1017  O  O   . LEU A 1 146 ? 208.374 212.352 263.572 1.00 53.14  ? 146 LEU A O   1 
ATOM   1018  C  CB  . LEU A 1 146 ? 206.893 214.572 265.381 1.00 49.77  ? 146 LEU A CB  1 
ATOM   1019  C  CG  . LEU A 1 146 ? 206.519 216.032 265.160 1.00 44.62  ? 146 LEU A CG  1 
ATOM   1020  C  CD1 . LEU A 1 146 ? 206.395 216.741 266.474 1.00 43.34  ? 146 LEU A CD1 1 
ATOM   1021  C  CD2 . LEU A 1 146 ? 207.568 216.694 264.303 1.00 48.21  ? 146 LEU A CD2 1 
ATOM   1022  N  N   . ILE A 1 147 ? 206.891 211.355 264.942 1.00 54.30  ? 147 ILE A N   1 
ATOM   1023  C  CA  . ILE A 1 147 ? 207.576 210.065 264.902 1.00 51.83  ? 147 ILE A CA  1 
ATOM   1024  C  C   . ILE A 1 147 ? 207.535 209.496 263.496 1.00 55.99  ? 147 ILE A C   1 
ATOM   1025  O  O   . ILE A 1 147 ? 208.554 209.053 262.954 1.00 59.03  ? 147 ILE A O   1 
ATOM   1026  C  CB  . ILE A 1 147 ? 206.949 209.088 265.911 1.00 48.01  ? 147 ILE A CB  1 
ATOM   1027  C  CG1 . ILE A 1 147 ? 207.287 209.485 267.342 1.00 51.50  ? 147 ILE A CG1 1 
ATOM   1028  C  CG2 . ILE A 1 147 ? 207.430 207.680 265.649 1.00 48.11  ? 147 ILE A CG2 1 
ATOM   1029  C  CD1 . ILE A 1 147 ? 206.322 208.939 268.361 1.00 53.24  ? 147 ILE A CD1 1 
ATOM   1030  N  N   . ILE A 1 148 ? 206.358 209.526 262.874 1.00 55.08  ? 148 ILE A N   1 
ATOM   1031  C  CA  . ILE A 1 148 ? 206.217 209.030 261.512 1.00 47.00  ? 148 ILE A CA  1 
ATOM   1032  C  C   . ILE A 1 148 ? 207.122 209.816 260.576 1.00 45.83  ? 148 ILE A C   1 
ATOM   1033  O  O   . ILE A 1 148 ? 207.774 209.255 259.690 1.00 47.22  ? 148 ILE A O   1 
ATOM   1034  C  CB  . ILE A 1 148 ? 204.746 209.103 261.075 1.00 42.44  ? 148 ILE A CB  1 
ATOM   1035  C  CG1 . ILE A 1 148 ? 204.012 207.826 261.475 1.00 47.84  ? 148 ILE A CG1 1 
ATOM   1036  C  CG2 . ILE A 1 148 ? 204.646 209.253 259.608 1.00 39.62  ? 148 ILE A CG2 1 
ATOM   1037  C  CD1 . ILE A 1 148 ? 204.306 206.638 260.585 1.00 53.86  ? 148 ILE A CD1 1 
ATOM   1038  N  N   . ALA A 1 149 ? 207.195 211.128 260.777 1.00 46.27  ? 149 ALA A N   1 
ATOM   1039  C  CA  . ALA A 1 149 ? 207.996 211.956 259.888 1.00 44.38  ? 149 ALA A CA  1 
ATOM   1040  C  C   . ALA A 1 149 ? 209.480 211.700 260.077 1.00 44.48  ? 149 ALA A C   1 
ATOM   1041  O  O   . ALA A 1 149 ? 210.222 211.613 259.095 1.00 49.09  ? 149 ALA A O   1 
ATOM   1042  C  CB  . ALA A 1 149 ? 207.678 213.432 260.110 1.00 44.67  ? 149 ALA A CB  1 
ATOM   1043  N  N   . VAL A 1 150 ? 209.939 211.581 261.325 1.00 45.71  ? 150 VAL A N   1 
ATOM   1044  C  CA  . VAL A 1 150 ? 211.373 211.414 261.558 1.00 49.25  ? 150 VAL A CA  1 
ATOM   1045  C  C   . VAL A 1 150 ? 211.811 210.020 261.135 1.00 50.00  ? 150 VAL A C   1 
ATOM   1046  O  O   . VAL A 1 150 ? 212.963 209.810 260.739 1.00 50.71  ? 150 VAL A O   1 
ATOM   1047  C  CB  . VAL A 1 150 ? 211.749 211.705 263.025 1.00 49.70  ? 150 VAL A CB  1 
ATOM   1048  C  CG1 . VAL A 1 150 ? 210.889 210.939 263.975 1.00 50.50  ? 150 VAL A CG1 1 
ATOM   1049  C  CG2 . VAL A 1 150 ? 213.216 211.406 263.279 1.00 50.59  ? 150 VAL A CG2 1 
ATOM   1050  N  N   . ASP A 1 151 ? 210.905 209.044 261.205 1.00 47.70  ? 151 ASP A N   1 
ATOM   1051  C  CA  . ASP A 1 151 ? 211.253 207.712 260.734 1.00 47.83  ? 151 ASP A CA  1 
ATOM   1052  C  C   . ASP A 1 151 ? 211.525 207.686 259.239 1.00 45.04  ? 151 ASP A C   1 
ATOM   1053  O  O   . ASP A 1 151 ? 212.246 206.802 258.769 1.00 48.82  ? 151 ASP A O   1 
ATOM   1054  C  CB  . ASP A 1 151 ? 210.150 206.712 261.068 1.00 54.74  ? 151 ASP A CB  1 
ATOM   1055  C  CG  . ASP A 1 151 ? 210.163 206.293 262.523 1.00 62.68  ? 151 ASP A CG  1 
ATOM   1056  O  OD1 . ASP A 1 151 ? 211.167 205.709 262.970 1.00 68.48  ? 151 ASP A OD1 1 
ATOM   1057  O  OD2 . ASP A 1 151 ? 209.146 206.495 263.215 1.00 64.63  ? 151 ASP A OD2 1 
ATOM   1058  N  N   . HIS A 1 152 ? 210.970 208.628 258.478 1.00 41.53  ? 152 HIS A N   1 
ATOM   1059  C  CA  . HIS A 1 152 ? 211.134 208.658 257.030 1.00 39.49  ? 152 HIS A CA  1 
ATOM   1060  C  C   . HIS A 1 152 ? 212.271 209.559 256.589 1.00 36.13  ? 152 HIS A C   1 
ATOM   1061  O  O   . HIS A 1 152 ? 212.236 210.110 255.485 1.00 38.87  ? 152 HIS A O   1 
ATOM   1062  C  CB  . HIS A 1 152 ? 209.838 209.086 256.357 1.00 38.95  ? 152 HIS A CB  1 
ATOM   1063  C  CG  . HIS A 1 152 ? 208.822 207.994 256.284 1.00 43.35  ? 152 HIS A CG  1 
ATOM   1064  N  ND1 . HIS A 1 152 ? 207.895 207.774 257.278 1.00 46.37  ? 152 HIS A ND1 1 
ATOM   1065  C  CD2 . HIS A 1 152 ? 208.601 207.046 255.347 1.00 44.25  ? 152 HIS A CD2 1 
ATOM   1066  C  CE1 . HIS A 1 152 ? 207.141 206.741 256.952 1.00 43.91  ? 152 HIS A CE1 1 
ATOM   1067  N  NE2 . HIS A 1 152 ? 207.548 206.282 255.784 1.00 43.30  ? 152 HIS A NE2 1 
ATOM   1068  N  N   . LEU A 1 153 ? 213.276 209.726 257.425 1.00 34.93  ? 153 LEU A N   1 
ATOM   1069  C  CA  . LEU A 1 153 ? 214.432 210.512 257.052 1.00 39.03  ? 153 LEU A CA  1 
ATOM   1070  C  C   . LEU A 1 153 ? 215.503 209.580 256.524 1.00 43.48  ? 153 LEU A C   1 
ATOM   1071  O  O   . LEU A 1 153 ? 215.755 208.518 257.094 1.00 45.04  ? 153 LEU A O   1 
ATOM   1072  C  CB  . LEU A 1 153 ? 214.947 211.313 258.244 1.00 49.14  ? 153 LEU A CB  1 
ATOM   1073  C  CG  . LEU A 1 153 ? 214.107 212.549 258.573 1.00 52.32  ? 153 LEU A CG  1 
ATOM   1074  C  CD1 . LEU A 1 153 ? 214.432 213.102 259.937 1.00 45.92  ? 153 LEU A CD1 1 
ATOM   1075  C  CD2 . LEU A 1 153 ? 214.294 213.611 257.514 1.00 52.91  ? 153 LEU A CD2 1 
ATOM   1076  N  N   . ASP A 1 154 ? 216.134 209.986 255.430 1.00 52.73  ? 154 ASP A N   1 
ATOM   1077  C  CA  . ASP A 1 154 ? 217.028 209.105 254.696 1.00 64.84  ? 154 ASP A CA  1 
ATOM   1078  C  C   . ASP A 1 154 ? 218.255 208.704 255.495 1.00 67.09  ? 154 ASP A C   1 
ATOM   1079  O  O   . ASP A 1 154 ? 218.971 207.789 255.075 1.00 69.47  ? 154 ASP A O   1 
ATOM   1080  C  CB  . ASP A 1 154 ? 217.459 209.777 253.391 1.00 72.69  ? 154 ASP A CB  1 
ATOM   1081  C  CG  . ASP A 1 154 ? 217.945 208.785 252.354 1.00 83.52  ? 154 ASP A CG  1 
ATOM   1082  O  OD1 . ASP A 1 154 ? 217.098 208.201 251.646 1.00 83.49  ? 154 ASP A OD1 1 
ATOM   1083  O  OD2 . ASP A 1 154 ? 219.174 208.592 252.243 1.00 87.81  ? 154 ASP A OD2 1 
ATOM   1084  N  N   . ARG A 1 155 ? 218.519 209.354 256.624 1.00 59.27  ? 155 ARG A N   1 
ATOM   1085  C  CA  . ARG A 1 155 ? 219.763 209.122 257.323 1.00 54.69  ? 155 ARG A CA  1 
ATOM   1086  C  C   . ARG A 1 155 ? 219.486 208.858 258.796 1.00 51.69  ? 155 ARG A C   1 
ATOM   1087  O  O   . ARG A 1 155 ? 218.557 209.440 259.362 1.00 50.76  ? 155 ARG A O   1 
ATOM   1088  C  CB  . ARG A 1 155 ? 220.678 210.340 257.155 1.00 54.37  ? 155 ARG A CB  1 
ATOM   1089  C  CG  . ARG A 1 155 ? 222.144 210.008 257.037 1.00 59.47  ? 155 ARG A CG  1 
ATOM   1090  C  CD  . ARG A 1 155 ? 223.023 211.199 257.375 1.00 63.61  ? 155 ARG A CD  1 
ATOM   1091  N  NE  . ARG A 1 155 ? 222.517 212.472 256.874 1.00 66.69  ? 155 ARG A NE  1 
ATOM   1092  C  CZ  . ARG A 1 155 ? 222.312 212.763 255.597 1.00 72.77  ? 155 ARG A CZ  1 
ATOM   1093  N  NH1 . ARG A 1 155 ? 222.587 211.897 254.635 1.00 70.69  ? 155 ARG A NH1 1 
ATOM   1094  N  NH2 . ARG A 1 155 ? 221.830 213.959 255.275 1.00 73.64  ? 155 ARG A NH2 1 
ATOM   1095  N  N   . PRO A 1 156 ? 220.244 207.969 259.432 1.00 49.34  ? 156 PRO A N   1 
ATOM   1096  C  CA  . PRO A 1 156 ? 220.023 207.697 260.852 1.00 49.29  ? 156 PRO A CA  1 
ATOM   1097  C  C   . PRO A 1 156 ? 220.414 208.879 261.718 1.00 55.34  ? 156 PRO A C   1 
ATOM   1098  O  O   . PRO A 1 156 ? 221.507 209.434 261.594 1.00 64.33  ? 156 PRO A O   1 
ATOM   1099  C  CB  . PRO A 1 156 ? 220.912 206.480 261.121 1.00 49.48  ? 156 PRO A CB  1 
ATOM   1100  C  CG  . PRO A 1 156 ? 221.197 205.922 259.805 1.00 48.48  ? 156 PRO A CG  1 
ATOM   1101  C  CD  . PRO A 1 156 ? 221.239 207.056 258.864 1.00 51.15  ? 156 PRO A CD  1 
ATOM   1102  N  N   . VAL A 1 157 ? 219.497 209.258 262.603 1.00 52.08  ? 157 VAL A N   1 
ATOM   1103  C  CA  . VAL A 1 157 ? 219.605 210.444 263.447 1.00 54.94  ? 157 VAL A CA  1 
ATOM   1104  C  C   . VAL A 1 157 ? 219.128 210.118 264.859 1.00 59.50  ? 157 VAL A C   1 
ATOM   1105  O  O   . VAL A 1 157 ? 218.148 209.392 265.047 1.00 60.54  ? 157 VAL A O   1 
ATOM   1106  C  CB  . VAL A 1 157 ? 218.826 211.618 262.829 1.00 53.95  ? 157 VAL A CB  1 
ATOM   1107  C  CG1 . VAL A 1 157 ? 219.089 211.729 261.357 1.00 60.52  ? 157 VAL A CG1 1 
ATOM   1108  C  CG2 . VAL A 1 157 ? 217.358 211.329 262.942 1.00 52.84  ? 157 VAL A CG2 1 
ATOM   1109  N  N   . ILE A 1 158 ? 219.846 210.648 265.858 1.00 62.52  ? 158 ILE A N   1 
ATOM   1110  C  CA  . ILE A 1 158 ? 219.603 210.367 267.275 1.00 55.76  ? 158 ILE A CA  1 
ATOM   1111  C  C   . ILE A 1 158 ? 219.639 211.666 268.066 1.00 55.56  ? 158 ILE A C   1 
ATOM   1112  O  O   . ILE A 1 158 ? 220.380 212.592 267.725 1.00 65.06  ? 158 ILE A O   1 
ATOM   1113  C  CB  . ILE A 1 158 ? 220.642 209.395 267.858 1.00 57.35  ? 158 ILE A CB  1 
ATOM   1114  C  CG1 . ILE A 1 158 ? 220.930 208.262 266.886 1.00 63.63  ? 158 ILE A CG1 1 
ATOM   1115  C  CG2 . ILE A 1 158 ? 220.149 208.833 269.174 1.00 61.76  ? 158 ILE A CG2 1 
ATOM   1116  C  CD1 . ILE A 1 158 ? 219.809 207.294 266.779 1.00 65.12  ? 158 ILE A CD1 1 
ATOM   1117  N  N   . VAL A 1 159 ? 218.856 211.731 269.128 1.00 52.29  ? 159 VAL A N   1 
ATOM   1118  C  CA  . VAL A 1 159 ? 218.895 212.866 270.043 1.00 63.78  ? 159 VAL A CA  1 
ATOM   1119  C  C   . VAL A 1 159 ? 219.572 212.426 271.337 1.00 76.87  ? 159 VAL A C   1 
ATOM   1120  O  O   . VAL A 1 159 ? 219.545 211.245 271.703 1.00 80.93  ? 159 VAL A O   1 
ATOM   1121  C  CB  . VAL A 1 159 ? 217.481 213.413 270.308 1.00 64.71  ? 159 VAL A CB  1 
ATOM   1122  C  CG1 . VAL A 1 159 ? 217.527 214.682 271.142 1.00 67.24  ? 159 VAL A CG1 1 
ATOM   1123  C  CG2 . VAL A 1 159 ? 216.773 213.659 269.007 1.00 62.14  ? 159 VAL A CG2 1 
ATOM   1124  N  N   . LEU A 1 160 ? 220.195 213.379 272.036 1.00 82.50  ? 160 LEU A N   1 
ATOM   1125  C  CA  . LEU A 1 160 ? 220.921 213.108 273.268 1.00 83.95  ? 160 LEU A CA  1 
ATOM   1126  C  C   . LEU A 1 160 ? 220.664 214.215 274.279 1.00 91.76  ? 160 LEU A C   1 
ATOM   1127  O  O   . LEU A 1 160 ? 220.413 215.368 273.915 1.00 92.49  ? 160 LEU A O   1 
ATOM   1128  C  CB  . LEU A 1 160 ? 222.423 212.996 273.024 1.00 81.74  ? 160 LEU A CB  1 
ATOM   1129  C  CG  . LEU A 1 160 ? 222.846 211.746 272.268 1.00 78.30  ? 160 LEU A CG  1 
ATOM   1130  C  CD1 . LEU A 1 160 ? 224.236 211.917 271.709 1.00 81.55  ? 160 LEU A CD1 1 
ATOM   1131  C  CD2 . LEU A 1 160 ? 222.795 210.555 273.169 1.00 81.48  ? 160 LEU A CD2 1 
ATOM   1132  N  N   . ASP A 1 161 ? 220.760 213.854 275.560 1.00 96.75  ? 161 ASP A N   1 
ATOM   1133  C  CA  . ASP A 1 161 ? 220.591 214.779 276.676 1.00 102.60 ? 161 ASP A CA  1 
ATOM   1134  C  C   . ASP A 1 161 ? 221.958 215.360 277.025 1.00 105.02 ? 161 ASP A C   1 
ATOM   1135  O  O   . ASP A 1 161 ? 222.947 215.001 276.374 1.00 104.67 ? 161 ASP A O   1 
ATOM   1136  C  CB  . ASP A 1 161 ? 219.947 214.069 277.874 1.00 100.72 ? 161 ASP A CB  1 
ATOM   1137  C  CG  . ASP A 1 161 ? 220.954 213.331 278.741 1.00 106.27 ? 161 ASP A CG  1 
ATOM   1138  O  OD1 . ASP A 1 161 ? 222.005 212.889 278.232 1.00 105.15 ? 161 ASP A OD1 1 
ATOM   1139  O  OD2 . ASP A 1 161 ? 220.690 213.198 279.955 1.00 110.59 ? 161 ASP A OD2 1 
ATOM   1140  N  N   . PRO A 1 162 ? 222.071 216.261 278.013 1.00 105.28 ? 162 PRO A N   1 
ATOM   1141  C  CA  . PRO A 1 162 ? 223.411 216.773 278.356 1.00 105.13 ? 162 PRO A CA  1 
ATOM   1142  C  C   . PRO A 1 162 ? 224.431 215.694 278.675 1.00 103.33 ? 162 PRO A C   1 
ATOM   1143  O  O   . PRO A 1 162 ? 225.571 215.783 278.205 1.00 101.29 ? 162 PRO A O   1 
ATOM   1144  C  CB  . PRO A 1 162 ? 223.140 217.681 279.568 1.00 102.63 ? 162 PRO A CB  1 
ATOM   1145  C  CG  . PRO A 1 162 ? 221.700 217.449 279.948 1.00 100.94 ? 162 PRO A CG  1 
ATOM   1146  C  CD  . PRO A 1 162 ? 221.022 217.034 278.696 1.00 101.77 ? 162 PRO A CD  1 
ATOM   1147  N  N   . GLU A 1 163 ? 224.058 214.656 279.416 1.00 101.22 ? 163 GLU A N   1 
ATOM   1148  C  CA  . GLU A 1 163 ? 225.016 213.618 279.766 1.00 98.17  ? 163 GLU A CA  1 
ATOM   1149  C  C   . GLU A 1 163 ? 225.067 212.534 278.699 1.00 97.98  ? 163 GLU A C   1 
ATOM   1150  O  O   . GLU A 1 163 ? 225.694 211.495 278.908 1.00 100.49 ? 163 GLU A O   1 
ATOM   1151  C  CB  . GLU A 1 163 ? 224.690 213.055 281.163 1.00 101.19 ? 163 GLU A CB  1 
ATOM   1152  C  CG  . GLU A 1 163 ? 223.474 212.150 281.301 1.00 103.49 ? 163 GLU A CG  1 
ATOM   1153  C  CD  . GLU A 1 163 ? 223.799 210.684 281.058 1.00 105.56 ? 163 GLU A CD  1 
ATOM   1154  O  OE1 . GLU A 1 163 ? 224.992 210.332 280.986 1.00 110.08 ? 163 GLU A OE1 1 
ATOM   1155  O  OE2 . GLU A 1 163 ? 222.867 209.872 280.946 1.00 102.25 ? 163 GLU A OE2 1 
ATOM   1156  N  N   . ARG A 1 164 ? 224.467 212.802 277.536 1.00 98.66  ? 164 ARG A N   1 
ATOM   1157  C  CA  . ARG A 1 164 ? 224.439 211.902 276.380 1.00 101.67 ? 164 ARG A CA  1 
ATOM   1158  C  C   . ARG A 1 164 ? 223.514 210.698 276.595 1.00 99.05  ? 164 ARG A C   1 
ATOM   1159  O  O   . ARG A 1 164 ? 223.838 209.577 276.202 1.00 94.59  ? 164 ARG A O   1 
ATOM   1160  C  CB  . ARG A 1 164 ? 225.851 211.439 275.991 1.00 102.73 ? 164 ARG A CB  1 
ATOM   1161  C  CG  . ARG A 1 164 ? 226.909 212.545 275.996 1.00 101.30 ? 164 ARG A CG  1 
ATOM   1162  C  CD  . ARG A 1 164 ? 226.722 213.502 274.836 1.00 98.66  ? 164 ARG A CD  1 
ATOM   1163  N  NE  . ARG A 1 164 ? 227.932 214.258 274.539 1.00 99.00  ? 164 ARG A NE  1 
ATOM   1164  C  CZ  . ARG A 1 164 ? 228.241 215.418 275.100 1.00 95.08  ? 164 ARG A CZ  1 
ATOM   1165  N  NH1 . ARG A 1 164 ? 227.458 215.979 276.004 1.00 92.53  ? 164 ARG A NH1 1 
ATOM   1166  N  NH2 . ARG A 1 164 ? 229.356 216.037 274.733 1.00 96.87  ? 164 ARG A NH2 1 
ATOM   1167  N  N   . HIS A 1 165 ? 222.339 210.926 277.183 1.00 98.17  ? 165 HIS A N   1 
ATOM   1168  C  CA  . HIS A 1 165 ? 221.300 209.899 277.172 1.00 95.89  ? 165 HIS A CA  1 
ATOM   1169  C  C   . HIS A 1 165 ? 220.760 209.725 275.758 1.00 92.32  ? 165 HIS A C   1 
ATOM   1170  O  O   . HIS A 1 165 ? 220.301 210.690 275.140 1.00 91.56  ? 165 HIS A O   1 
ATOM   1171  C  CB  . HIS A 1 165 ? 220.139 210.268 278.099 1.00 95.87  ? 165 HIS A CB  1 
ATOM   1172  C  CG  . HIS A 1 165 ? 220.253 209.725 279.489 1.00 95.68  ? 165 HIS A CG  1 
ATOM   1173  N  ND1 . HIS A 1 165 ? 220.525 208.401 279.756 1.00 96.47  ? 165 HIS A ND1 1 
ATOM   1174  C  CD2 . HIS A 1 165 ? 220.064 210.318 280.692 1.00 96.86  ? 165 HIS A CD2 1 
ATOM   1175  C  CE1 . HIS A 1 165 ? 220.535 208.208 281.063 1.00 96.02  ? 165 HIS A CE1 1 
ATOM   1176  N  NE2 . HIS A 1 165 ? 220.263 209.357 281.654 1.00 97.98  ? 165 HIS A NE2 1 
ATOM   1177  N  N   . ILE A 1 166 ? 220.773 208.491 275.256 1.00 89.59  ? 166 ILE A N   1 
ATOM   1178  C  CA  . ILE A 1 166 ? 220.148 208.208 273.969 1.00 77.84  ? 166 ILE A CA  1 
ATOM   1179  C  C   . ILE A 1 166 ? 218.647 208.232 274.185 1.00 73.81  ? 166 ILE A C   1 
ATOM   1180  O  O   . ILE A 1 166 ? 218.047 207.235 274.600 1.00 80.99  ? 166 ILE A O   1 
ATOM   1181  C  CB  . ILE A 1 166 ? 220.615 206.863 273.388 1.00 73.64  ? 166 ILE A CB  1 
ATOM   1182  C  CG1 . ILE A 1 166 ? 222.095 206.948 273.024 1.00 82.81  ? 166 ILE A CG1 1 
ATOM   1183  C  CG2 . ILE A 1 166 ? 219.770 206.465 272.199 1.00 68.49  ? 166 ILE A CG2 1 
ATOM   1184  C  CD1 . ILE A 1 166 ? 222.365 207.285 271.577 1.00 81.06  ? 166 ILE A CD1 1 
ATOM   1185  N  N   . VAL A 1 167 ? 218.031 209.373 273.916 1.00 66.55  ? 167 VAL A N   1 
ATOM   1186  C  CA  . VAL A 1 167 ? 216.631 209.544 274.263 1.00 67.77  ? 167 VAL A CA  1 
ATOM   1187  C  C   . VAL A 1 167 ? 215.712 209.152 273.113 1.00 75.67  ? 167 VAL A C   1 
ATOM   1188  O  O   . VAL A 1 167 ? 214.685 208.506 273.334 1.00 82.65  ? 167 VAL A O   1 
ATOM   1189  C  CB  . VAL A 1 167 ? 216.385 210.988 274.723 1.00 65.92  ? 167 VAL A CB  1 
ATOM   1190  C  CG1 . VAL A 1 167 ? 216.815 211.143 276.163 1.00 75.73  ? 167 VAL A CG1 1 
ATOM   1191  C  CG2 . VAL A 1 167 ? 217.144 211.946 273.848 1.00 70.21  ? 167 VAL A CG2 1 
ATOM   1192  N  N   . GLN A 1 168 ? 216.044 209.518 271.875 1.00 72.30  ? 168 GLN A N   1 
ATOM   1193  C  CA  . GLN A 1 168 ? 215.167 209.234 270.744 1.00 62.79  ? 168 GLN A CA  1 
ATOM   1194  C  C   . GLN A 1 168 ? 215.978 208.832 269.526 1.00 57.11  ? 168 GLN A C   1 
ATOM   1195  O  O   . GLN A 1 168 ? 216.807 209.608 269.042 1.00 60.02  ? 168 GLN A O   1 
ATOM   1196  C  CB  . GLN A 1 168 ? 214.273 210.432 270.434 1.00 56.83  ? 168 GLN A CB  1 
ATOM   1197  C  CG  . GLN A 1 168 ? 213.164 210.569 271.453 1.00 56.67  ? 168 GLN A CG  1 
ATOM   1198  C  CD  . GLN A 1 168 ? 212.258 211.735 271.191 1.00 60.69  ? 168 GLN A CD  1 
ATOM   1199  O  OE1 . GLN A 1 168 ? 212.461 212.494 270.245 1.00 66.93  ? 168 GLN A OE1 1 
ATOM   1200  N  NE2 . GLN A 1 168 ? 211.231 211.880 272.019 1.00 56.74  ? 168 GLN A NE2 1 
ATOM   1201  N  N   . CYS A 1 169 ? 215.737 207.617 269.051 1.00 52.24  ? 169 CYS A N   1 
ATOM   1202  C  CA  . CYS A 1 169 ? 216.256 207.096 267.802 1.00 60.84  ? 169 CYS A CA  1 
ATOM   1203  C  C   . CYS A 1 169 ? 215.110 206.988 266.806 1.00 67.09  ? 169 CYS A C   1 
ATOM   1204  O  O   . CYS A 1 169 ? 213.953 207.264 267.133 1.00 70.33  ? 169 CYS A O   1 
ATOM   1205  C  CB  . CYS A 1 169 ? 216.914 205.731 268.010 1.00 63.86  ? 169 CYS A CB  1 
ATOM   1206  S  SG  . CYS A 1 169 ? 215.834 204.500 268.765 1.00 88.90  ? 169 CYS A SG  1 
ATOM   1207  N  N   . ASN A 1 170 ? 215.434 206.595 265.577 1.00 62.62  ? 170 ASN A N   1 
ATOM   1208  C  CA  . ASN A 1 170 ? 214.432 206.506 264.527 1.00 55.61  ? 170 ASN A CA  1 
ATOM   1209  C  C   . ASN A 1 170 ? 214.633 205.228 263.728 1.00 54.23  ? 170 ASN A C   1 
ATOM   1210  O  O   . ASN A 1 170 ? 215.585 204.477 263.944 1.00 58.36  ? 170 ASN A O   1 
ATOM   1211  C  CB  . ASN A 1 170 ? 214.488 207.731 263.615 1.00 53.16  ? 170 ASN A CB  1 
ATOM   1212  C  CG  . ASN A 1 170 ? 215.778 207.823 262.876 1.00 56.63  ? 170 ASN A CG  1 
ATOM   1213  O  OD1 . ASN A 1 170 ? 216.791 207.296 263.322 1.00 57.55  ? 170 ASN A OD1 1 
ATOM   1214  N  ND2 . ASN A 1 170 ? 215.762 208.496 261.738 1.00 59.50  ? 170 ASN A ND2 1 
ATOM   1215  N  N   . ARG A 1 171 ? 213.725 204.995 262.783 1.00 53.23  ? 171 ARG A N   1 
ATOM   1216  C  CA  . ARG A 1 171 ? 213.712 203.731 262.064 1.00 50.76  ? 171 ARG A CA  1 
ATOM   1217  C  C   . ARG A 1 171 ? 214.984 203.519 261.268 1.00 52.01  ? 171 ARG A C   1 
ATOM   1218  O  O   . ARG A 1 171 ? 215.417 202.378 261.103 1.00 59.46  ? 171 ARG A O   1 
ATOM   1219  C  CB  . ARG A 1 171 ? 212.501 203.657 261.139 1.00 53.57  ? 171 ARG A CB  1 
ATOM   1220  C  CG  . ARG A 1 171 ? 212.475 202.435 260.239 1.00 56.88  ? 171 ARG A CG  1 
ATOM   1221  C  CD  . ARG A 1 171 ? 211.050 202.018 259.895 1.00 58.04  ? 171 ARG A CD  1 
ATOM   1222  N  NE  . ARG A 1 171 ? 210.225 203.113 259.396 1.00 59.03  ? 171 ARG A NE  1 
ATOM   1223  C  CZ  . ARG A 1 171 ? 210.473 203.820 258.301 1.00 57.61  ? 171 ARG A CZ  1 
ATOM   1224  N  NH1 . ARG A 1 171 ? 211.506 203.553 257.517 1.00 60.81  ? 171 ARG A NH1 1 
ATOM   1225  N  NH2 . ARG A 1 171 ? 209.652 204.813 257.973 1.00 54.52  ? 171 ARG A NH2 1 
ATOM   1226  N  N   . ALA A 1 172 ? 215.597 204.584 260.766 1.00 48.64  ? 172 ALA A N   1 
ATOM   1227  C  CA  . ALA A 1 172 ? 216.847 204.414 260.042 1.00 52.75  ? 172 ALA A CA  1 
ATOM   1228  C  C   . ALA A 1 172 ? 217.922 203.842 260.951 1.00 60.83  ? 172 ALA A C   1 
ATOM   1229  O  O   . ALA A 1 172 ? 218.713 202.990 260.533 1.00 65.08  ? 172 ALA A O   1 
ATOM   1230  C  CB  . ALA A 1 172 ? 217.291 205.743 259.444 1.00 51.05  ? 172 ALA A CB  1 
ATOM   1231  N  N   . PHE A 1 173 ? 217.965 204.297 262.204 1.00 62.62  ? 173 PHE A N   1 
ATOM   1232  C  CA  . PHE A 1 173 ? 218.940 203.782 263.161 1.00 62.25  ? 173 PHE A CA  1 
ATOM   1233  C  C   . PHE A 1 173 ? 218.638 202.342 263.553 1.00 60.58  ? 173 PHE A C   1 
ATOM   1234  O  O   . PHE A 1 173 ? 219.554 201.531 263.711 1.00 62.29  ? 173 PHE A O   1 
ATOM   1235  C  CB  . PHE A 1 173 ? 218.959 204.681 264.386 1.00 59.43  ? 173 PHE A CB  1 
ATOM   1236  C  CG  . PHE A 1 173 ? 219.969 204.296 265.403 1.00 60.77  ? 173 PHE A CG  1 
ATOM   1237  C  CD1 . PHE A 1 173 ? 221.289 204.633 265.230 1.00 65.92  ? 173 PHE A CD1 1 
ATOM   1238  C  CD2 . PHE A 1 173 ? 219.589 203.652 266.562 1.00 68.27  ? 173 PHE A CD2 1 
ATOM   1239  C  CE1 . PHE A 1 173 ? 222.218 204.312 266.177 1.00 75.98  ? 173 PHE A CE1 1 
ATOM   1240  C  CE2 . PHE A 1 173 ? 220.517 203.319 267.514 1.00 78.04  ? 173 PHE A CE2 1 
ATOM   1241  C  CZ  . PHE A 1 173 ? 221.838 203.648 267.320 1.00 81.24  ? 173 PHE A CZ  1 
ATOM   1242  N  N   . THR A 1 174 ? 217.359 202.012 263.727 1.00 59.19  ? 174 THR A N   1 
ATOM   1243  C  CA  . THR A 1 174 ? 216.974 200.633 263.998 1.00 60.49  ? 174 THR A CA  1 
ATOM   1244  C  C   . THR A 1 174 ? 217.398 199.724 262.859 1.00 61.14  ? 174 THR A C   1 
ATOM   1245  O  O   . THR A 1 174 ? 218.076 198.714 263.068 1.00 67.63  ? 174 THR A O   1 
ATOM   1246  C  CB  . THR A 1 174 ? 215.462 200.547 264.205 1.00 64.25  ? 174 THR A CB  1 
ATOM   1247  O  OG1 . THR A 1 174 ? 215.098 201.253 265.395 1.00 66.20  ? 174 THR A OG1 1 
ATOM   1248  C  CG2 . THR A 1 174 ? 215.023 199.101 264.323 1.00 66.76  ? 174 THR A CG2 1 
ATOM   1249  N  N   . GLU A 1 175 ? 217.029 200.087 261.637 1.00 58.82  ? 175 GLU A N   1 
ATOM   1250  C  CA  . GLU A 1 175 ? 217.390 199.319 260.463 1.00 58.02  ? 175 GLU A CA  1 
ATOM   1251  C  C   . GLU A 1 175 ? 218.866 199.414 260.144 1.00 58.15  ? 175 GLU A C   1 
ATOM   1252  O  O   . GLU A 1 175 ? 219.336 198.694 259.260 1.00 65.32  ? 175 GLU A O   1 
ATOM   1253  C  CB  . GLU A 1 175 ? 216.558 199.778 259.273 1.00 59.99  ? 175 GLU A CB  1 
ATOM   1254  C  CG  . GLU A 1 175 ? 215.069 199.771 259.554 1.00 61.49  ? 175 GLU A CG  1 
ATOM   1255  C  CD  . GLU A 1 175 ? 214.232 199.785 258.296 1.00 68.55  ? 175 GLU A CD  1 
ATOM   1256  O  OE1 . GLU A 1 175 ? 212.989 199.756 258.406 1.00 70.05  ? 175 GLU A OE1 1 
ATOM   1257  O  OE2 . GLU A 1 175 ? 214.816 199.825 257.195 1.00 70.25  ? 175 GLU A OE2 1 
ATOM   1258  N  N   . MET A 1 176 ? 219.606 200.280 260.822 1.00 55.20  ? 176 MET A N   1 
ATOM   1259  C  CA  . MET A 1 176 ? 221.044 200.270 260.620 1.00 66.02  ? 176 MET A CA  1 
ATOM   1260  C  C   . MET A 1 176 ? 221.756 199.326 261.589 1.00 78.00  ? 176 MET A C   1 
ATOM   1261  O  O   . MET A 1 176 ? 222.701 198.635 261.191 1.00 81.89  ? 176 MET A O   1 
ATOM   1262  C  CB  . MET A 1 176 ? 221.597 201.693 260.728 1.00 69.27  ? 176 MET A CB  1 
ATOM   1263  C  CG  . MET A 1 176 ? 223.086 201.760 260.976 1.00 77.17  ? 176 MET A CG  1 
ATOM   1264  S  SD  . MET A 1 176 ? 224.064 201.959 259.478 1.00 92.61  ? 176 MET A SD  1 
ATOM   1265  C  CE  . MET A 1 176 ? 223.839 203.697 259.144 1.00 74.29  ? 176 MET A CE  1 
ATOM   1266  N  N   . PHE A 1 177 ? 221.318 199.263 262.852 1.00 77.55  ? 177 PHE A N   1 
ATOM   1267  C  CA  . PHE A 1 177 ? 221.894 198.338 263.827 1.00 67.40  ? 177 PHE A CA  1 
ATOM   1268  C  C   . PHE A 1 177 ? 220.893 197.286 264.279 1.00 69.03  ? 177 PHE A C   1 
ATOM   1269  O  O   . PHE A 1 177 ? 221.163 196.090 264.146 1.00 73.12  ? 177 PHE A O   1 
ATOM   1270  C  CB  . PHE A 1 177 ? 222.424 199.102 265.042 1.00 63.71  ? 177 PHE A CB  1 
ATOM   1271  C  CG  . PHE A 1 177 ? 223.462 200.111 264.705 1.00 64.89  ? 177 PHE A CG  1 
ATOM   1272  C  CD1 . PHE A 1 177 ? 224.315 199.912 263.649 1.00 68.65  ? 177 PHE A CD1 1 
ATOM   1273  C  CD2 . PHE A 1 177 ? 223.585 201.261 265.444 1.00 67.69  ? 177 PHE A CD2 1 
ATOM   1274  C  CE1 . PHE A 1 177 ? 225.270 200.844 263.336 1.00 72.08  ? 177 PHE A CE1 1 
ATOM   1275  C  CE2 . PHE A 1 177 ? 224.539 202.193 265.134 1.00 75.02  ? 177 PHE A CE2 1 
ATOM   1276  C  CZ  . PHE A 1 177 ? 225.380 201.983 264.076 1.00 76.67  ? 177 PHE A CZ  1 
ATOM   1277  N  N   . GLY A 1 178 ? 219.738 197.695 264.800 1.00 72.12  ? 178 GLY A N   1 
ATOM   1278  C  CA  . GLY A 1 178 ? 218.732 196.767 265.279 1.00 72.96  ? 178 GLY A CA  1 
ATOM   1279  C  C   . GLY A 1 178 ? 217.984 197.263 266.500 1.00 75.46  ? 178 GLY A C   1 
ATOM   1280  O  O   . GLY A 1 178 ? 216.974 196.677 266.896 1.00 75.06  ? 178 GLY A O   1 
ATOM   1281  N  N   . TYR A 1 179 ? 218.456 198.357 267.089 1.00 73.58  ? 179 TYR A N   1 
ATOM   1282  C  CA  . TYR A 1 179 ? 217.923 198.815 268.364 1.00 68.91  ? 179 TYR A CA  1 
ATOM   1283  C  C   . TYR A 1 179 ? 216.596 199.526 268.180 1.00 69.59  ? 179 TYR A C   1 
ATOM   1284  O  O   . TYR A 1 179 ? 216.414 200.302 267.240 1.00 75.52  ? 179 TYR A O   1 
ATOM   1285  C  CB  . TYR A 1 179 ? 218.905 199.761 269.044 1.00 69.06  ? 179 TYR A CB  1 
ATOM   1286  C  CG  . TYR A 1 179 ? 220.200 199.125 269.488 1.00 77.16  ? 179 TYR A CG  1 
ATOM   1287  C  CD1 . TYR A 1 179 ? 220.546 197.838 269.103 1.00 79.27  ? 179 TYR A CD1 1 
ATOM   1288  C  CD2 . TYR A 1 179 ? 221.080 199.818 270.298 1.00 82.02  ? 179 TYR A CD2 1 
ATOM   1289  C  CE1 . TYR A 1 179 ? 221.728 197.263 269.513 1.00 82.33  ? 179 TYR A CE1 1 
ATOM   1290  C  CE2 . TYR A 1 179 ? 222.259 199.253 270.710 1.00 85.08  ? 179 TYR A CE2 1 
ATOM   1291  C  CZ  . TYR A 1 179 ? 222.583 197.978 270.318 1.00 86.59  ? 179 TYR A CZ  1 
ATOM   1292  O  OH  . TYR A 1 179 ? 223.769 197.421 270.736 1.00 91.19  ? 179 TYR A OH  1 
ATOM   1293  N  N   . CYS A 1 180 ? 215.672 199.269 269.091 1.00 65.69  ? 180 CYS A N   1 
ATOM   1294  C  CA  . CYS A 1 180 ? 214.404 199.971 269.126 1.00 69.38  ? 180 CYS A CA  1 
ATOM   1295  C  C   . CYS A 1 180 ? 214.466 201.073 270.177 1.00 73.73  ? 180 CYS A C   1 
ATOM   1296  O  O   . CYS A 1 180 ? 215.446 201.213 270.910 1.00 75.50  ? 180 CYS A O   1 
ATOM   1297  C  CB  . CYS A 1 180 ? 213.261 198.997 269.404 1.00 74.77  ? 180 CYS A CB  1 
ATOM   1298  S  SG  . CYS A 1 180 ? 213.533 197.334 268.763 1.00 85.10  ? 180 CYS A SG  1 
ATOM   1299  N  N   . ILE A 1 181 ? 213.402 201.870 270.251 1.00 78.02  ? 181 ILE A N   1 
ATOM   1300  C  CA  . ILE A 1 181 ? 213.381 202.982 271.193 1.00 85.14  ? 181 ILE A CA  1 
ATOM   1301  C  C   . ILE A 1 181 ? 213.431 202.471 272.629 1.00 86.86  ? 181 ILE A C   1 
ATOM   1302  O  O   . ILE A 1 181 ? 214.143 203.025 273.473 1.00 86.05  ? 181 ILE A O   1 
ATOM   1303  C  CB  . ILE A 1 181 ? 212.150 203.873 270.940 1.00 86.73  ? 181 ILE A CB  1 
ATOM   1304  C  CG1 . ILE A 1 181 ? 212.044 204.967 272.005 1.00 84.72  ? 181 ILE A CG1 1 
ATOM   1305  C  CG2 . ILE A 1 181 ? 210.874 203.040 270.869 1.00 83.56  ? 181 ILE A CG2 1 
ATOM   1306  C  CD1 . ILE A 1 181 ? 213.237 205.894 272.050 1.00 76.93  ? 181 ILE A CD1 1 
ATOM   1307  N  N   . SER A 1 182 ? 212.689 201.402 272.926 1.00 85.50  ? 182 SER A N   1 
ATOM   1308  C  CA  . SER A 1 182 ? 212.660 200.874 274.286 1.00 83.43  ? 182 SER A CA  1 
ATOM   1309  C  C   . SER A 1 182 ? 213.972 200.199 274.660 1.00 79.75  ? 182 SER A C   1 
ATOM   1310  O  O   . SER A 1 182 ? 214.360 200.207 275.833 1.00 79.29  ? 182 SER A O   1 
ATOM   1311  C  CB  . SER A 1 182 ? 211.507 199.885 274.440 1.00 78.91  ? 182 SER A CB  1 
ATOM   1312  O  OG  . SER A 1 182 ? 211.600 198.849 273.479 1.00 72.46  ? 182 SER A OG  1 
ATOM   1313  N  N   . GLU A 1 183 ? 214.663 199.612 273.685 1.00 75.27  ? 183 GLU A N   1 
ATOM   1314  C  CA  . GLU A 1 183 ? 215.827 198.796 273.999 1.00 72.35  ? 183 GLU A CA  1 
ATOM   1315  C  C   . GLU A 1 183 ? 217.016 199.652 274.418 1.00 74.71  ? 183 GLU A C   1 
ATOM   1316  O  O   . GLU A 1 183 ? 217.790 199.256 275.296 1.00 78.45  ? 183 GLU A O   1 
ATOM   1317  C  CB  . GLU A 1 183 ? 216.181 197.924 272.798 1.00 71.68  ? 183 GLU A CB  1 
ATOM   1318  C  CG  . GLU A 1 183 ? 217.225 196.874 273.080 1.00 70.94  ? 183 GLU A CG  1 
ATOM   1319  C  CD  . GLU A 1 183 ? 218.627 197.357 272.796 1.00 79.22  ? 183 GLU A CD  1 
ATOM   1320  O  OE1 . GLU A 1 183 ? 218.772 198.462 272.234 1.00 82.69  ? 183 GLU A OE1 1 
ATOM   1321  O  OE2 . GLU A 1 183 ? 219.584 196.631 273.132 1.00 81.74  ? 183 GLU A OE2 1 
ATOM   1322  N  N   . ALA A 1 184 ? 217.186 200.819 273.803 1.00 72.53  ? 184 ALA A N   1 
ATOM   1323  C  CA  . ALA A 1 184 ? 218.308 201.702 274.096 1.00 73.53  ? 184 ALA A CA  1 
ATOM   1324  C  C   . ALA A 1 184 ? 217.842 203.079 274.548 1.00 79.74  ? 184 ALA A C   1 
ATOM   1325  O  O   . ALA A 1 184 ? 218.368 204.097 274.097 1.00 78.42  ? 184 ALA A O   1 
ATOM   1326  C  CB  . ALA A 1 184 ? 219.223 201.828 272.882 1.00 74.64  ? 184 ALA A CB  1 
ATOM   1327  N  N   . SER A 1 185 ? 216.863 203.120 275.446 1.00 84.33  ? 185 SER A N   1 
ATOM   1328  C  CA  . SER A 1 185 ? 216.236 204.366 275.880 1.00 85.60  ? 185 SER A CA  1 
ATOM   1329  C  C   . SER A 1 185 ? 217.067 205.000 276.984 1.00 84.64  ? 185 SER A C   1 
ATOM   1330  O  O   . SER A 1 185 ? 217.013 204.576 278.139 1.00 84.97  ? 185 SER A O   1 
ATOM   1331  C  CB  . SER A 1 185 ? 214.817 204.102 276.365 1.00 87.50  ? 185 SER A CB  1 
ATOM   1332  O  OG  . SER A 1 185 ? 214.784 204.008 277.777 1.00 92.32  ? 185 SER A OG  1 
ATOM   1333  N  N   . GLY A 1 186 ? 217.827 206.032 276.633 1.00 85.82  ? 186 GLY A N   1 
ATOM   1334  C  CA  . GLY A 1 186 ? 218.596 206.752 277.633 1.00 86.74  ? 186 GLY A CA  1 
ATOM   1335  C  C   . GLY A 1 186 ? 219.575 205.872 278.373 1.00 87.20  ? 186 GLY A C   1 
ATOM   1336  O  O   . GLY A 1 186 ? 219.551 205.824 279.608 1.00 91.84  ? 186 GLY A O   1 
ATOM   1337  N  N   . MET A 1 187 ? 220.428 205.156 277.647 1.00 82.01  ? 187 MET A N   1 
ATOM   1338  C  CA  . MET A 1 187 ? 221.322 204.198 278.272 1.00 86.08  ? 187 MET A CA  1 
ATOM   1339  C  C   . MET A 1 187 ? 222.771 204.381 277.834 1.00 89.23  ? 187 MET A C   1 
ATOM   1340  O  O   . MET A 1 187 ? 223.592 203.485 278.045 1.00 99.37  ? 187 MET A O   1 
ATOM   1341  C  CB  . MET A 1 187 ? 220.771 202.781 278.040 1.00 86.51  ? 187 MET A CB  1 
ATOM   1342  C  CG  . MET A 1 187 ? 221.028 202.020 276.734 1.00 87.59  ? 187 MET A CG  1 
ATOM   1343  S  SD  . MET A 1 187 ? 222.681 201.675 276.126 1.00 101.57 ? 187 MET A SD  1 
ATOM   1344  C  CE  . MET A 1 187 ? 223.187 200.397 277.274 1.00 96.85  ? 187 MET A CE  1 
ATOM   1345  N  N   . GLN A 1 188 ? 223.109 205.567 277.302 1.00 83.62  ? 188 GLN A N   1 
ATOM   1346  C  CA  . GLN A 1 188 ? 224.465 206.000 276.982 1.00 89.53  ? 188 GLN A CA  1 
ATOM   1347  C  C   . GLN A 1 188 ? 224.906 205.355 275.677 1.00 93.50  ? 188 GLN A C   1 
ATOM   1348  O  O   . GLN A 1 188 ? 224.795 204.133 275.512 1.00 91.54  ? 188 GLN A O   1 
ATOM   1349  C  CB  . GLN A 1 188 ? 225.452 205.657 278.105 1.00 98.93  ? 188 GLN A CB  1 
ATOM   1350  C  CG  . GLN A 1 188 ? 226.546 206.680 278.387 1.00 100.63 ? 188 GLN A CG  1 
ATOM   1351  C  CD  . GLN A 1 188 ? 226.011 208.058 278.705 1.00 98.65  ? 188 GLN A CD  1 
ATOM   1352  O  OE1 . GLN A 1 188 ? 225.696 208.834 277.809 1.00 92.86  ? 188 GLN A OE1 1 
ATOM   1353  N  NE2 . GLN A 1 188 ? 225.910 208.371 279.991 1.00 103.78 ? 188 GLN A NE2 1 
ATOM   1354  N  N   . PRO A 1 189 ? 225.431 206.141 274.737 1.00 97.85  ? 189 PRO A N   1 
ATOM   1355  C  CA  . PRO A 1 189 ? 225.700 205.590 273.399 1.00 100.84 ? 189 PRO A CA  1 
ATOM   1356  C  C   . PRO A 1 189 ? 226.850 204.604 273.382 1.00 101.69 ? 189 PRO A C   1 
ATOM   1357  O  O   . PRO A 1 189 ? 226.756 203.551 272.738 1.00 99.81  ? 189 PRO A O   1 
ATOM   1358  C  CB  . PRO A 1 189 ? 226.004 206.844 272.564 1.00 98.74  ? 189 PRO A CB  1 
ATOM   1359  C  CG  . PRO A 1 189 ? 225.564 208.012 273.411 1.00 97.94  ? 189 PRO A CG  1 
ATOM   1360  C  CD  . PRO A 1 189 ? 225.759 207.570 274.817 1.00 96.17  ? 189 PRO A CD  1 
ATOM   1361  N  N   . ASP A 1 190 ? 227.939 204.919 274.085 1.00 104.44 ? 190 ASP A N   1 
ATOM   1362  C  CA  . ASP A 1 190 ? 229.118 204.061 274.062 1.00 107.34 ? 190 ASP A CA  1 
ATOM   1363  C  C   . ASP A 1 190 ? 228.785 202.644 274.504 1.00 107.35 ? 190 ASP A C   1 
ATOM   1364  O  O   . ASP A 1 190 ? 229.373 201.676 274.009 1.00 109.07 ? 190 ASP A O   1 
ATOM   1365  C  CB  . ASP A 1 190 ? 230.207 204.659 274.950 1.00 111.38 ? 190 ASP A CB  1 
ATOM   1366  C  CG  . ASP A 1 190 ? 231.587 204.476 274.371 1.00 115.85 ? 190 ASP A CG  1 
ATOM   1367  O  OD1 . ASP A 1 190 ? 232.375 205.444 274.373 1.00 117.24 ? 190 ASP A OD1 1 
ATOM   1368  O  OD2 . ASP A 1 190 ? 231.884 203.355 273.920 1.00 115.76 ? 190 ASP A OD2 1 
ATOM   1369  N  N   . THR A 1 191 ? 227.837 202.504 275.432 1.00 108.22 ? 191 THR A N   1 
ATOM   1370  C  CA  . THR A 1 191 ? 227.452 201.177 275.898 1.00 110.09 ? 191 THR A CA  1 
ATOM   1371  C  C   . THR A 1 191 ? 226.572 200.459 274.880 1.00 108.90 ? 191 THR A C   1 
ATOM   1372  O  O   . THR A 1 191 ? 226.623 199.228 274.772 1.00 109.62 ? 191 THR A O   1 
ATOM   1373  C  CB  . THR A 1 191 ? 226.742 201.280 277.248 1.00 108.50 ? 191 THR A CB  1 
ATOM   1374  O  OG1 . THR A 1 191 ? 227.377 202.286 278.047 1.00 106.73 ? 191 THR A OG1 1 
ATOM   1375  C  CG2 . THR A 1 191 ? 226.803 199.949 277.983 1.00 105.55 ? 191 THR A CG2 1 
ATOM   1376  N  N   . LEU A 1 192 ? 225.761 201.202 274.122 1.00 104.25 ? 192 LEU A N   1 
ATOM   1377  C  CA  . LEU A 1 192 ? 224.900 200.567 273.131 1.00 102.21 ? 192 LEU A CA  1 
ATOM   1378  C  C   . LEU A 1 192 ? 225.552 200.450 271.767 1.00 99.08  ? 192 LEU A C   1 
ATOM   1379  O  O   . LEU A 1 192 ? 225.221 199.533 271.010 1.00 95.18  ? 192 LEU A O   1 
ATOM   1380  C  CB  . LEU A 1 192 ? 223.583 201.331 272.975 1.00 103.23 ? 192 LEU A CB  1 
ATOM   1381  C  CG  . LEU A 1 192 ? 223.559 202.768 272.455 1.00 103.91 ? 192 LEU A CG  1 
ATOM   1382  C  CD1 . LEU A 1 192 ? 223.338 202.814 270.949 1.00 100.53 ? 192 LEU A CD1 1 
ATOM   1383  C  CD2 . LEU A 1 192 ? 222.463 203.526 273.163 1.00 97.49  ? 192 LEU A CD2 1 
ATOM   1384  N  N   . LEU A 1 193 ? 226.473 201.351 271.437 1.00 100.73 ? 193 LEU A N   1 
ATOM   1385  C  CA  . LEU A 1 193 ? 227.019 201.381 270.090 1.00 107.32 ? 193 LEU A CA  1 
ATOM   1386  C  C   . LEU A 1 193 ? 227.859 200.154 269.769 1.00 109.77 ? 193 LEU A C   1 
ATOM   1387  O  O   . LEU A 1 193 ? 228.194 199.950 268.597 1.00 114.78 ? 193 LEU A O   1 
ATOM   1388  C  CB  . LEU A 1 193 ? 227.845 202.651 269.889 1.00 109.31 ? 193 LEU A CB  1 
ATOM   1389  C  CG  . LEU A 1 193 ? 227.551 203.403 268.591 1.00 106.65 ? 193 LEU A CG  1 
ATOM   1390  C  CD1 . LEU A 1 193 ? 226.069 203.731 268.492 1.00 101.09 ? 193 LEU A CD1 1 
ATOM   1391  C  CD2 . LEU A 1 193 ? 228.388 204.668 268.497 1.00 101.89 ? 193 LEU A CD2 1 
ATOM   1392  N  N   . ASN A 1 194 ? 228.195 199.338 270.769 1.00 107.48 ? 194 ASN A N   1 
ATOM   1393  C  CA  . ASN A 1 194 ? 228.995 198.131 270.578 1.00 113.05 ? 194 ASN A CA  1 
ATOM   1394  C  C   . ASN A 1 194 ? 230.299 198.467 269.855 1.00 115.47 ? 194 ASN A C   1 
ATOM   1395  O  O   . ASN A 1 194 ? 230.682 197.839 268.867 1.00 116.33 ? 194 ASN A O   1 
ATOM   1396  C  CB  . ASN A 1 194 ? 228.201 197.057 269.826 1.00 110.99 ? 194 ASN A CB  1 
ATOM   1397  C  CG  . ASN A 1 194 ? 228.740 195.660 270.066 1.00 112.03 ? 194 ASN A CG  1 
ATOM   1398  O  OD1 . ASN A 1 194 ? 229.675 195.467 270.843 1.00 117.49 ? 194 ASN A OD1 1 
ATOM   1399  N  ND2 . ASN A 1 194 ? 228.151 194.676 269.396 1.00 101.89 ? 194 ASN A ND2 1 
ATOM   1400  N  N   . THR A 1 195 ? 230.971 199.489 270.372 1.00 114.63 ? 195 THR A N   1 
ATOM   1401  C  CA  . THR A 1 195 ? 232.186 200.012 269.758 1.00 118.97 ? 195 THR A CA  1 
ATOM   1402  C  C   . THR A 1 195 ? 233.251 198.923 269.772 1.00 123.65 ? 195 THR A C   1 
ATOM   1403  O  O   . THR A 1 195 ? 233.215 198.030 270.632 1.00 124.00 ? 195 THR A O   1 
ATOM   1404  C  CB  . THR A 1 195 ? 232.684 201.270 270.493 1.00 30.00  ? 195 THR A CB  1 
ATOM   1405  O  OG1 . THR A 1 195 ? 232.920 200.960 271.871 1.00 30.00  ? 195 THR A OG1 1 
ATOM   1406  C  CG2 . THR A 1 195 ? 231.586 202.322 270.554 1.00 30.00  ? 195 THR A CG2 1 
ATOM   1407  N  N   . PRO A 1 196 ? 234.186 198.929 268.829 1.00 123.39 ? 196 PRO A N   1 
ATOM   1408  C  CA  . PRO A 1 196 ? 235.240 197.913 268.836 1.00 125.93 ? 196 PRO A CA  1 
ATOM   1409  C  C   . PRO A 1 196 ? 236.162 198.076 270.034 1.00 132.30 ? 196 PRO A C   1 
ATOM   1410  O  O   . PRO A 1 196 ? 236.370 199.179 270.546 1.00 131.75 ? 196 PRO A O   1 
ATOM   1411  C  CB  . PRO A 1 196 ? 235.984 198.167 267.521 1.00 122.14 ? 196 PRO A CB  1 
ATOM   1412  C  CG  . PRO A 1 196 ? 235.729 199.600 267.227 1.00 119.14 ? 196 PRO A CG  1 
ATOM   1413  C  CD  . PRO A 1 196 ? 234.339 199.872 267.710 1.00 118.00 ? 196 PRO A CD  1 
ATOM   1414  N  N   . GLU A 1 197 ? 236.713 196.951 270.484 1.00 135.11 ? 197 GLU A N   1 
ATOM   1415  C  CA  . GLU A 1 197 ? 237.627 196.931 271.619 1.00 137.67 ? 197 GLU A CA  1 
ATOM   1416  C  C   . GLU A 1 197 ? 239.092 196.921 271.203 1.00 140.55 ? 197 GLU A C   1 
ATOM   1417  O  O   . GLU A 1 197 ? 239.921 197.556 271.862 1.00 138.91 ? 197 GLU A O   1 
ATOM   1418  C  CB  . GLU A 1 197 ? 237.340 195.713 272.505 1.00 135.89 ? 197 GLU A CB  1 
ATOM   1419  C  CG  . GLU A 1 197 ? 238.197 195.634 273.758 1.00 136.27 ? 197 GLU A CG  1 
ATOM   1420  C  CD  . GLU A 1 197 ? 237.780 194.506 274.680 1.00 135.42 ? 197 GLU A CD  1 
ATOM   1421  O  OE1 . GLU A 1 197 ? 237.061 193.594 274.219 1.00 133.88 ? 197 GLU A OE1 1 
ATOM   1422  O  OE2 . GLU A 1 197 ? 238.170 194.530 275.867 1.00 135.55 ? 197 GLU A OE2 1 
ATOM   1423  N  N   . PHE A 1 198 ? 239.428 196.214 270.124 1.00 142.83 ? 198 PHE A N   1 
ATOM   1424  C  CA  . PHE A 1 198 ? 240.824 196.133 269.695 1.00 143.09 ? 198 PHE A CA  1 
ATOM   1425  C  C   . PHE A 1 198 ? 241.412 197.483 269.299 1.00 139.96 ? 198 PHE A C   1 
ATOM   1426  O  O   . PHE A 1 198 ? 242.512 197.811 269.777 1.00 136.65 ? 198 PHE A O   1 
ATOM   1427  C  CB  . PHE A 1 198 ? 240.954 195.106 268.564 1.00 142.96 ? 198 PHE A CB  1 
ATOM   1428  C  CG  . PHE A 1 198 ? 240.324 193.777 268.875 1.00 144.36 ? 198 PHE A CG  1 
ATOM   1429  C  CD1 . PHE A 1 198 ? 240.899 192.924 269.803 1.00 144.94 ? 198 PHE A CD1 1 
ATOM   1430  C  CD2 . PHE A 1 198 ? 239.160 193.379 268.238 1.00 142.64 ? 198 PHE A CD2 1 
ATOM   1431  C  CE1 . PHE A 1 198 ? 240.323 191.700 270.092 1.00 143.03 ? 198 PHE A CE1 1 
ATOM   1432  C  CE2 . PHE A 1 198 ? 238.580 192.157 268.523 1.00 141.53 ? 198 PHE A CE2 1 
ATOM   1433  C  CZ  . PHE A 1 198 ? 239.162 191.316 269.451 1.00 142.06 ? 198 PHE A CZ  1 
ATOM   1434  N  N   . PRO A 1 199 ? 240.769 198.310 268.452 1.00 137.66 ? 199 PRO A N   1 
ATOM   1435  C  CA  . PRO A 1 199 ? 241.397 199.587 268.088 1.00 134.38 ? 199 PRO A CA  1 
ATOM   1436  C  C   . PRO A 1 199 ? 241.269 200.631 269.183 1.00 135.24 ? 199 PRO A C   1 
ATOM   1437  O  O   . PRO A 1 199 ? 240.190 201.192 269.396 1.00 134.14 ? 199 PRO A O   1 
ATOM   1438  C  CB  . PRO A 1 199 ? 240.637 200.005 266.825 1.00 129.08 ? 199 PRO A CB  1 
ATOM   1439  C  CG  . PRO A 1 199 ? 239.305 199.397 266.983 1.00 128.94 ? 199 PRO A CG  1 
ATOM   1440  C  CD  . PRO A 1 199 ? 239.517 198.093 267.702 1.00 134.54 ? 199 PRO A CD  1 
ATOM   1441  N  N   . ALA A 1 200 ? 242.372 200.899 269.883 1.00 136.83 ? 200 ALA A N   1 
ATOM   1442  C  CA  . ALA A 1 200 ? 242.349 201.896 270.949 1.00 136.07 ? 200 ALA A CA  1 
ATOM   1443  C  C   . ALA A 1 200 ? 242.127 203.296 270.390 1.00 135.58 ? 200 ALA A C   1 
ATOM   1444  O  O   . ALA A 1 200 ? 241.345 204.078 270.942 1.00 133.38 ? 200 ALA A O   1 
ATOM   1445  C  CB  . ALA A 1 200 ? 243.647 201.833 271.754 1.00 132.16 ? 200 ALA A CB  1 
ATOM   1446  N  N   . ASP A 1 201 ? 242.810 203.630 269.292 1.00 138.58 ? 201 ASP A N   1 
ATOM   1447  C  CA  . ASP A 1 201 ? 242.673 204.961 268.708 1.00 134.91 ? 201 ASP A CA  1 
ATOM   1448  C  C   . ASP A 1 201 ? 241.256 205.207 268.209 1.00 131.58 ? 201 ASP A C   1 
ATOM   1449  O  O   . ASP A 1 201 ? 240.692 206.286 268.422 1.00 127.55 ? 201 ASP A O   1 
ATOM   1450  C  CB  . ASP A 1 201 ? 243.682 205.140 267.574 1.00 135.79 ? 201 ASP A CB  1 
ATOM   1451  C  CG  . ASP A 1 201 ? 243.573 204.054 266.522 1.00 137.17 ? 201 ASP A CG  1 
ATOM   1452  O  OD1 . ASP A 1 201 ? 243.050 202.966 266.843 1.00 139.87 ? 201 ASP A OD1 1 
ATOM   1453  O  OD2 . ASP A 1 201 ? 244.010 204.287 265.375 1.00 134.18 ? 201 ASP A OD2 1 
ATOM   1454  N  N   . ASN A 1 202 ? 240.661 204.213 267.550 1.00 133.65 ? 202 ASN A N   1 
ATOM   1455  C  CA  . ASN A 1 202 ? 239.310 204.372 267.025 1.00 129.44 ? 202 ASN A CA  1 
ATOM   1456  C  C   . ASN A 1 202 ? 238.308 204.605 268.147 1.00 128.13 ? 202 ASN A C   1 
ATOM   1457  O  O   . ASN A 1 202 ? 237.481 205.523 268.077 1.00 126.29 ? 202 ASN A O   1 
ATOM   1458  C  CB  . ASN A 1 202 ? 238.926 203.140 266.207 1.00 125.28 ? 202 ASN A CB  1 
ATOM   1459  C  CG  . ASN A 1 202 ? 237.697 203.367 265.357 1.00 119.01 ? 202 ASN A CG  1 
ATOM   1460  O  OD1 . ASN A 1 202 ? 237.780 203.916 264.259 1.00 117.61 ? 202 ASN A OD1 1 
ATOM   1461  N  ND2 . ASN A 1 202 ? 236.543 202.944 265.860 1.00 116.99 ? 202 ASN A ND2 1 
ATOM   1462  N  N   . ARG A 1 203 ? 238.374 203.788 269.201 1.00 128.26 ? 203 ARG A N   1 
ATOM   1463  C  CA  . ARG A 1 203 ? 237.410 203.919 270.289 1.00 125.56 ? 203 ARG A CA  1 
ATOM   1464  C  C   . ARG A 1 203 ? 237.637 205.202 271.078 1.00 126.03 ? 203 ARG A C   1 
ATOM   1465  O  O   . ARG A 1 203 ? 236.676 205.841 271.520 1.00 120.78 ? 203 ARG A O   1 
ATOM   1466  C  CB  . ARG A 1 203 ? 237.468 202.690 271.196 1.00 125.82 ? 203 ARG A CB  1 
ATOM   1467  C  CG  . ARG A 1 203 ? 238.752 202.519 271.976 1.00 130.76 ? 203 ARG A CG  1 
ATOM   1468  C  CD  . ARG A 1 203 ? 238.934 201.074 272.406 1.00 133.53 ? 203 ARG A CD  1 
ATOM   1469  N  NE  . ARG A 1 203 ? 237.662 200.431 272.713 1.00 133.88 ? 203 ARG A NE  1 
ATOM   1470  C  CZ  . ARG A 1 203 ? 237.074 200.461 273.901 1.00 135.64 ? 203 ARG A CZ  1 
ATOM   1471  N  NH1 . ARG A 1 203 ? 237.616 201.100 274.925 1.00 134.43 ? 203 ARG A NH1 1 
ATOM   1472  N  NH2 . ARG A 1 203 ? 235.914 199.832 274.066 1.00 132.30 ? 203 ARG A NH2 1 
ATOM   1473  N  N   . ILE A 1 204 ? 238.899 205.607 271.250 1.00 129.84 ? 204 ILE A N   1 
ATOM   1474  C  CA  . ILE A 1 204 ? 239.194 206.862 271.936 1.00 128.68 ? 204 ILE A CA  1 
ATOM   1475  C  C   . ILE A 1 204 ? 238.640 208.041 271.144 1.00 125.32 ? 204 ILE A C   1 
ATOM   1476  O  O   . ILE A 1 204 ? 238.014 208.950 271.703 1.00 120.47 ? 204 ILE A O   1 
ATOM   1477  C  CB  . ILE A 1 204 ? 240.709 207.000 272.176 1.00 127.71 ? 204 ILE A CB  1 
ATOM   1478  C  CG1 . ILE A 1 204 ? 241.137 206.161 273.383 1.00 125.86 ? 204 ILE A CG1 1 
ATOM   1479  C  CG2 . ILE A 1 204 ? 241.096 208.458 272.378 1.00 121.70 ? 204 ILE A CG2 1 
ATOM   1480  C  CD1 . ILE A 1 204 ? 242.629 205.905 273.450 1.00 127.00 ? 204 ILE A CD1 1 
ATOM   1481  N  N   . ARG A 1 205 ? 238.855 208.037 269.825 1.00 127.72 ? 205 ARG A N   1 
ATOM   1482  C  CA  . ARG A 1 205 ? 238.339 209.113 268.987 1.00 124.75 ? 205 ARG A CA  1 
ATOM   1483  C  C   . ARG A 1 205 ? 236.817 209.146 269.015 1.00 122.12 ? 205 ARG A C   1 
ATOM   1484  O  O   . ARG A 1 205 ? 236.214 210.222 269.093 1.00 118.13 ? 205 ARG A O   1 
ATOM   1485  C  CB  . ARG A 1 205 ? 238.851 208.948 267.556 1.00 125.09 ? 205 ARG A CB  1 
ATOM   1486  C  CG  . ARG A 1 205 ? 240.309 209.341 267.374 1.00 124.63 ? 205 ARG A CG  1 
ATOM   1487  C  CD  . ARG A 1 205 ? 240.743 209.231 265.921 1.00 123.80 ? 205 ARG A CD  1 
ATOM   1488  N  NE  . ARG A 1 205 ? 240.817 207.845 265.474 1.00 128.99 ? 205 ARG A NE  1 
ATOM   1489  C  CZ  . ARG A 1 205 ? 239.998 207.301 264.584 1.00 126.68 ? 205 ARG A CZ  1 
ATOM   1490  N  NH1 . ARG A 1 205 ? 239.024 208.000 264.024 1.00 120.71 ? 205 ARG A NH1 1 
ATOM   1491  N  NH2 . ARG A 1 205 ? 240.163 206.026 264.245 1.00 128.80 ? 205 ARG A NH2 1 
ATOM   1492  N  N   . LEU A 1 206 ? 236.178 207.975 268.961 1.00 122.41 ? 206 LEU A N   1 
ATOM   1493  C  CA  . LEU A 1 206 ? 234.721 207.924 269.032 1.00 118.82 ? 206 LEU A CA  1 
ATOM   1494  C  C   . LEU A 1 206 ? 234.217 208.463 270.361 1.00 116.52 ? 206 LEU A C   1 
ATOM   1495  O  O   . LEU A 1 206 ? 233.240 209.222 270.403 1.00 115.69 ? 206 LEU A O   1 
ATOM   1496  C  CB  . LEU A 1 206 ? 234.238 206.490 268.822 1.00 117.87 ? 206 LEU A CB  1 
ATOM   1497  C  CG  . LEU A 1 206 ? 232.732 206.245 268.943 1.00 114.65 ? 206 LEU A CG  1 
ATOM   1498  C  CD1 . LEU A 1 206 ? 231.947 207.197 268.052 1.00 112.34 ? 206 LEU A CD1 1 
ATOM   1499  C  CD2 . LEU A 1 206 ? 232.402 204.800 268.608 1.00 111.39 ? 206 LEU A CD2 1 
ATOM   1500  N  N   . GLN A 1 207 ? 234.869 208.081 271.459 1.00 115.05 ? 207 GLN A N   1 
ATOM   1501  C  CA  . GLN A 1 207 ? 234.417 208.528 272.768 1.00 117.37 ? 207 GLN A CA  1 
ATOM   1502  C  C   . GLN A 1 207 ? 234.592 210.037 272.902 1.00 118.88 ? 207 GLN A C   1 
ATOM   1503  O  O   . GLN A 1 207 ? 233.724 210.733 273.445 1.00 117.52 ? 207 GLN A O   1 
ATOM   1504  C  CB  . GLN A 1 207 ? 235.193 207.797 273.861 1.00 117.87 ? 207 GLN A CB  1 
ATOM   1505  C  CG  . GLN A 1 207 ? 234.761 208.093 275.298 1.00 120.90 ? 207 GLN A CG  1 
ATOM   1506  C  CD  . GLN A 1 207 ? 233.246 208.090 275.493 1.00 118.70 ? 207 GLN A CD  1 
ATOM   1507  O  OE1 . GLN A 1 207 ? 232.528 208.972 275.028 1.00 115.83 ? 207 GLN A OE1 1 
ATOM   1508  N  NE2 . GLN A 1 207 ? 232.758 207.074 276.194 1.00 120.29 ? 207 GLN A NE2 1 
ATOM   1509  N  N   . GLN A 1 208 ? 235.708 210.564 272.391 1.00 118.32 ? 208 GLN A N   1 
ATOM   1510  C  CA  . GLN A 1 208 ? 235.925 212.007 272.412 1.00 117.40 ? 208 GLN A CA  1 
ATOM   1511  C  C   . GLN A 1 208 ? 234.880 212.729 271.574 1.00 112.75 ? 208 GLN A C   1 
ATOM   1512  O  O   . GLN A 1 208 ? 234.377 213.789 271.968 1.00 107.32 ? 208 GLN A O   1 
ATOM   1513  C  CB  . GLN A 1 208 ? 237.330 212.332 271.906 1.00 121.18 ? 208 GLN A CB  1 
ATOM   1514  C  CG  . GLN A 1 208 ? 238.444 211.995 272.884 1.00 123.10 ? 208 GLN A CG  1 
ATOM   1515  C  CD  . GLN A 1 208 ? 239.824 212.190 272.284 1.00 122.15 ? 208 GLN A CD  1 
ATOM   1516  O  OE1 . GLN A 1 208 ? 239.961 212.480 271.095 1.00 122.26 ? 208 GLN A OE1 1 
ATOM   1517  N  NE2 . GLN A 1 208 ? 240.856 212.023 273.104 1.00 119.10 ? 208 GLN A NE2 1 
ATOM   1518  N  N   . LEU A 1 209 ? 234.549 212.172 270.408 1.00 114.37 ? 209 LEU A N   1 
ATOM   1519  C  CA  . LEU A 1 209 ? 233.519 212.764 269.563 1.00 114.01 ? 209 LEU A CA  1 
ATOM   1520  C  C   . LEU A 1 209 ? 232.185 212.808 270.287 1.00 113.57 ? 209 LEU A C   1 
ATOM   1521  O  O   . LEU A 1 209 ? 231.462 213.808 270.218 1.00 110.94 ? 209 LEU A O   1 
ATOM   1522  C  CB  . LEU A 1 209 ? 233.399 211.971 268.263 1.00 114.58 ? 209 LEU A CB  1 
ATOM   1523  C  CG  . LEU A 1 209 ? 232.215 212.305 267.355 1.00 112.46 ? 209 LEU A CG  1 
ATOM   1524  C  CD1 . LEU A 1 209 ? 232.675 212.465 265.917 1.00 105.06 ? 209 LEU A CD1 1 
ATOM   1525  C  CD2 . LEU A 1 209 ? 231.135 211.239 267.464 1.00 106.69 ? 209 LEU A CD2 1 
ATOM   1526  N  N   . LEU A 1 210 ? 231.843 211.730 270.989 1.00 114.53 ? 210 LEU A N   1 
ATOM   1527  C  CA  . LEU A 1 210 ? 230.632 211.742 271.797 1.00 112.20 ? 210 LEU A CA  1 
ATOM   1528  C  C   . LEU A 1 210 ? 230.725 212.761 272.924 1.00 111.97 ? 210 LEU A C   1 
ATOM   1529  O  O   . LEU A 1 210 ? 229.702 213.312 273.348 1.00 110.69 ? 210 LEU A O   1 
ATOM   1530  C  CB  . LEU A 1 210 ? 230.364 210.350 272.365 1.00 111.88 ? 210 LEU A CB  1 
ATOM   1531  C  CG  . LEU A 1 210 ? 229.173 210.232 273.312 1.00 106.08 ? 210 LEU A CG  1 
ATOM   1532  C  CD1 . LEU A 1 210 ? 227.901 210.670 272.618 1.00 102.23 ? 210 LEU A CD1 1 
ATOM   1533  C  CD2 . LEU A 1 210 ? 229.051 208.812 273.823 1.00 105.28 ? 210 LEU A CD2 1 
ATOM   1534  N  N   . TRP A 1 211 ? 231.935 213.041 273.409 1.00 112.48 ? 211 TRP A N   1 
ATOM   1535  C  CA  . TRP A 1 211 ? 232.086 213.895 274.578 1.00 111.11 ? 211 TRP A CA  1 
ATOM   1536  C  C   . TRP A 1 211 ? 232.329 215.362 274.260 1.00 111.15 ? 211 TRP A C   1 
ATOM   1537  O  O   . TRP A 1 211 ? 231.640 216.218 274.826 1.00 109.81 ? 211 TRP A O   1 
ATOM   1538  C  CB  . TRP A 1 211 ? 233.213 213.376 275.469 1.00 108.65 ? 211 TRP A CB  1 
ATOM   1539  C  CG  . TRP A 1 211 ? 232.690 212.461 276.505 1.00 107.81 ? 211 TRP A CG  1 
ATOM   1540  C  CD1 . TRP A 1 211 ? 233.030 211.162 276.693 1.00 108.02 ? 211 TRP A CD1 1 
ATOM   1541  C  CD2 . TRP A 1 211 ? 231.707 212.770 277.499 1.00 110.31 ? 211 TRP A CD2 1 
ATOM   1542  N  NE1 . TRP A 1 211 ? 232.323 210.633 277.744 1.00 110.64 ? 211 TRP A NE1 1 
ATOM   1543  C  CE2 . TRP A 1 211 ? 231.505 211.604 278.259 1.00 112.89 ? 211 TRP A CE2 1 
ATOM   1544  C  CE3 . TRP A 1 211 ? 230.982 213.923 277.826 1.00 108.06 ? 211 TRP A CE3 1 
ATOM   1545  C  CZ2 . TRP A 1 211 ? 230.608 211.555 279.326 1.00 111.96 ? 211 TRP A CZ2 1 
ATOM   1546  C  CZ3 . TRP A 1 211 ? 230.093 213.872 278.881 1.00 107.48 ? 211 TRP A CZ3 1 
ATOM   1547  C  CH2 . TRP A 1 211 ? 229.913 212.696 279.619 1.00 108.90 ? 211 TRP A CH2 1 
ATOM   1548  N  N   . LYS A 1 212 ? 233.280 215.692 273.396 1.00 109.48 ? 212 LYS A N   1 
ATOM   1549  C  CA  . LYS A 1 212 ? 233.570 217.092 273.137 1.00 105.18 ? 212 LYS A CA  1 
ATOM   1550  C  C   . LYS A 1 212 ? 232.400 217.751 272.422 1.00 102.39 ? 212 LYS A C   1 
ATOM   1551  O  O   . LYS A 1 212 ? 231.709 217.130 271.611 1.00 104.08 ? 212 LYS A O   1 
ATOM   1552  C  CB  . LYS A 1 212 ? 234.858 217.254 272.328 1.00 106.69 ? 212 LYS A CB  1 
ATOM   1553  C  CG  . LYS A 1 212 ? 234.745 216.991 270.843 1.00 105.15 ? 212 LYS A CG  1 
ATOM   1554  C  CD  . LYS A 1 212 ? 236.138 216.854 270.242 1.00 106.42 ? 212 LYS A CD  1 
ATOM   1555  C  CE  . LYS A 1 212 ? 236.501 215.410 269.952 1.00 111.43 ? 212 LYS A CE  1 
ATOM   1556  N  NZ  . LYS A 1 212 ? 235.803 214.901 268.743 1.00 113.22 ? 212 LYS A NZ  1 
ATOM   1557  N  N   . THR A 1 213 ? 232.174 219.023 272.745 1.00 98.17  ? 213 THR A N   1 
ATOM   1558  C  CA  . THR A 1 213 ? 230.989 219.751 272.299 1.00 98.22  ? 213 THR A CA  1 
ATOM   1559  C  C   . THR A 1 213 ? 231.267 220.601 271.071 1.00 101.64 ? 213 THR A C   1 
ATOM   1560  O  O   . THR A 1 213 ? 230.729 221.702 270.932 1.00 100.81 ? 213 THR A O   1 
ATOM   1561  C  CB  . THR A 1 213 ? 230.436 220.614 273.426 1.00 95.62  ? 213 THR A CB  1 
ATOM   1562  O  OG1 . THR A 1 213 ? 229.487 221.541 272.887 1.00 97.08  ? 213 THR A OG1 1 
ATOM   1563  C  CG2 . THR A 1 213 ? 231.553 221.386 274.096 1.00 97.10  ? 213 THR A CG2 1 
ATOM   1564  N  N   . ALA A 1 214 ? 232.108 220.118 270.168 1.00 104.92 ? 214 ALA A N   1 
ATOM   1565  C  CA  . ALA A 1 214 ? 232.353 220.774 268.896 1.00 102.36 ? 214 ALA A CA  1 
ATOM   1566  C  C   . ALA A 1 214 ? 231.577 220.059 267.792 1.00 104.70 ? 214 ALA A C   1 
ATOM   1567  O  O   . ALA A 1 214 ? 231.074 218.946 267.967 1.00 108.27 ? 214 ALA A O   1 
ATOM   1568  C  CB  . ALA A 1 214 ? 233.852 220.811 268.590 1.00 98.87  ? 214 ALA A CB  1 
ATOM   1569  N  N   . ARG A 1 215 ? 231.486 220.718 266.639 1.00 101.41 ? 215 ARG A N   1 
ATOM   1570  C  CA  . ARG A 1 215 ? 230.846 220.154 265.450 1.00 98.49  ? 215 ARG A CA  1 
ATOM   1571  C  C   . ARG A 1 215 ? 231.851 219.237 264.764 1.00 98.89  ? 215 ARG A C   1 
ATOM   1572  O  O   . ARG A 1 215 ? 232.635 219.658 263.913 1.00 101.59 ? 215 ARG A O   1 
ATOM   1573  C  CB  . ARG A 1 215 ? 230.357 221.273 264.538 1.00 97.68  ? 215 ARG A CB  1 
ATOM   1574  C  CG  . ARG A 1 215 ? 229.689 220.831 263.244 1.00 97.34  ? 215 ARG A CG  1 
ATOM   1575  C  CD  . ARG A 1 215 ? 228.943 219.518 263.376 1.00 95.10  ? 215 ARG A CD  1 
ATOM   1576  N  NE  . ARG A 1 215 ? 228.764 218.871 262.082 1.00 96.69  ? 215 ARG A NE  1 
ATOM   1577  C  CZ  . ARG A 1 215 ? 229.741 218.326 261.367 1.00 96.27  ? 215 ARG A CZ  1 
ATOM   1578  N  NH1 . ARG A 1 215 ? 230.994 218.330 261.790 1.00 98.28  ? 215 ARG A NH1 1 
ATOM   1579  N  NH2 . ARG A 1 215 ? 229.452 217.764 260.197 1.00 92.26  ? 215 ARG A NH2 1 
ATOM   1580  N  N   . ASP A 1 216 ? 231.818 217.961 265.135 1.00 96.87  ? 216 ASP A N   1 
ATOM   1581  C  CA  . ASP A 1 216 ? 232.753 216.967 264.630 1.00 97.59  ? 216 ASP A CA  1 
ATOM   1582  C  C   . ASP A 1 216 ? 232.101 216.130 263.543 1.00 94.47  ? 216 ASP A C   1 
ATOM   1583  O  O   . ASP A 1 216 ? 230.897 215.864 263.586 1.00 93.64  ? 216 ASP A O   1 
ATOM   1584  C  CB  . ASP A 1 216 ? 233.234 216.047 265.749 1.00 102.03 ? 216 ASP A CB  1 
ATOM   1585  C  CG  . ASP A 1 216 ? 233.686 216.805 266.969 1.00 106.45 ? 216 ASP A CG  1 
ATOM   1586  O  OD1 . ASP A 1 216 ? 233.665 218.052 266.941 1.00 105.91 ? 216 ASP A OD1 1 
ATOM   1587  O  OD2 . ASP A 1 216 ? 234.052 216.148 267.961 1.00 109.13 ? 216 ASP A OD2 1 
ATOM   1588  N  N   . GLN A 1 217 ? 232.904 215.713 262.572 1.00 95.47  ? 217 GLN A N   1 
ATOM   1589  C  CA  . GLN A 1 217 ? 232.443 214.889 261.463 1.00 94.86  ? 217 GLN A CA  1 
ATOM   1590  C  C   . GLN A 1 217 ? 233.399 213.729 261.244 1.00 95.21  ? 217 GLN A C   1 
ATOM   1591  O  O   . GLN A 1 217 ? 233.781 213.405 260.118 1.00 96.39  ? 217 GLN A O   1 
ATOM   1592  C  CB  . GLN A 1 217 ? 232.296 215.717 260.190 1.00 98.63  ? 217 GLN A CB  1 
ATOM   1593  C  CG  . GLN A 1 217 ? 233.396 216.747 259.990 1.00 101.66 ? 217 GLN A CG  1 
ATOM   1594  C  CD  . GLN A 1 217 ? 233.111 217.692 258.840 1.00 100.78 ? 217 GLN A CD  1 
ATOM   1595  O  OE1 . GLN A 1 217 ? 232.027 217.671 258.258 1.00 99.43  ? 217 GLN A OE1 1 
ATOM   1596  N  NE2 . GLN A 1 217 ? 234.088 218.526 258.504 1.00 99.34  ? 217 GLN A NE2 1 
ATOM   1597  N  N   . ASP A 1 218 ? 233.801 213.086 262.329 1.00 94.59  ? 218 ASP A N   1 
ATOM   1598  C  CA  . ASP A 1 218 ? 234.753 211.994 262.235 1.00 104.03 ? 218 ASP A CA  1 
ATOM   1599  C  C   . ASP A 1 218 ? 234.044 210.690 261.871 1.00 106.28 ? 218 ASP A C   1 
ATOM   1600  O  O   . ASP A 1 218 ? 232.822 210.566 261.966 1.00 104.64 ? 218 ASP A O   1 
ATOM   1601  C  CB  . ASP A 1 218 ? 235.521 211.848 263.545 1.00 106.44 ? 218 ASP A CB  1 
ATOM   1602  C  CG  . ASP A 1 218 ? 236.949 211.383 263.334 1.00 111.17 ? 218 ASP A CG  1 
ATOM   1603  O  OD1 . ASP A 1 218 ? 237.445 211.482 262.192 1.00 111.33 ? 218 ASP A OD1 1 
ATOM   1604  O  OD2 . ASP A 1 218 ? 237.574 210.916 264.309 1.00 114.17 ? 218 ASP A OD2 1 
ATOM   1605  N  N   . GLU A 1 219 ? 234.836 209.705 261.446 1.00 106.33 ? 219 GLU A N   1 
ATOM   1606  C  CA  . GLU A 1 219 ? 234.321 208.419 261.002 1.00 102.28 ? 219 GLU A CA  1 
ATOM   1607  C  C   . GLU A 1 219 ? 234.940 207.299 261.823 1.00 102.49 ? 219 GLU A C   1 
ATOM   1608  O  O   . GLU A 1 219 ? 236.108 207.365 262.211 1.00 103.69 ? 219 GLU A O   1 
ATOM   1609  C  CB  . GLU A 1 219 ? 234.604 208.178 259.515 1.00 103.62 ? 219 GLU A CB  1 
ATOM   1610  C  CG  . GLU A 1 219 ? 236.059 208.330 259.129 1.00 107.22 ? 219 GLU A CG  1 
ATOM   1611  C  CD  . GLU A 1 219 ? 236.372 209.704 258.578 1.00 108.73 ? 219 GLU A CD  1 
ATOM   1612  O  OE1 . GLU A 1 219 ? 235.926 210.703 259.179 1.00 106.42 ? 219 GLU A OE1 1 
ATOM   1613  O  OE2 . GLU A 1 219 ? 237.062 209.785 257.540 1.00 107.37 ? 219 GLU A OE2 1 
ATOM   1614  N  N   . PHE A 1 220 ? 234.142 206.265 262.084 1.00 104.29 ? 220 PHE A N   1 
ATOM   1615  C  CA  . PHE A 1 220 ? 234.575 205.160 262.927 1.00 102.97 ? 220 PHE A CA  1 
ATOM   1616  C  C   . PHE A 1 220 ? 233.947 203.862 262.448 1.00 100.28 ? 220 PHE A C   1 
ATOM   1617  O  O   . PHE A 1 220 ? 232.948 203.857 261.724 1.00 101.14 ? 220 PHE A O   1 
ATOM   1618  C  CB  . PHE A 1 220 ? 234.212 205.393 264.393 1.00 103.97 ? 220 PHE A CB  1 
ATOM   1619  C  CG  . PHE A 1 220 ? 234.361 206.816 264.836 1.00 108.72 ? 220 PHE A CG  1 
ATOM   1620  C  CD1 . PHE A 1 220 ? 235.569 207.279 265.321 1.00 112.78 ? 220 PHE A CD1 1 
ATOM   1621  C  CD2 . PHE A 1 220 ? 233.292 207.691 264.770 1.00 106.21 ? 220 PHE A CD2 1 
ATOM   1622  C  CE1 . PHE A 1 220 ? 235.708 208.588 265.730 1.00 111.96 ? 220 PHE A CE1 1 
ATOM   1623  C  CE2 . PHE A 1 220 ? 233.425 208.999 265.177 1.00 107.33 ? 220 PHE A CE2 1 
ATOM   1624  C  CZ  . PHE A 1 220 ? 234.633 209.446 265.662 1.00 110.19 ? 220 PHE A CZ  1 
ATOM   1625  N  N   . LEU A 1 221 ? 234.540 202.755 262.877 1.00 98.56  ? 221 LEU A N   1 
ATOM   1626  C  CA  . LEU A 1 221 ? 234.009 201.431 262.590 1.00 98.23  ? 221 LEU A CA  1 
ATOM   1627  C  C   . LEU A 1 221 ? 233.115 200.993 263.737 1.00 99.19  ? 221 LEU A C   1 
ATOM   1628  O  O   . LEU A 1 221 ? 233.482 201.127 264.906 1.00 102.30 ? 221 LEU A O   1 
ATOM   1629  C  CB  . LEU A 1 221 ? 235.133 200.414 262.409 1.00 101.93 ? 221 LEU A CB  1 
ATOM   1630  C  CG  . LEU A 1 221 ? 235.669 200.173 261.001 1.00 103.61 ? 221 LEU A CG  1 
ATOM   1631  C  CD1 . LEU A 1 221 ? 234.815 199.152 260.275 1.00 105.03 ? 221 LEU A CD1 1 
ATOM   1632  C  CD2 . LEU A 1 221 ? 235.744 201.464 260.232 1.00 100.44 ? 221 LEU A CD2 1 
ATOM   1633  N  N   . LEU A 1 222 ? 231.939 200.477 263.406 1.00 99.96  ? 222 LEU A N   1 
ATOM   1634  C  CA  . LEU A 1 222 ? 231.001 200.011 264.417 1.00 99.32  ? 222 LEU A CA  1 
ATOM   1635  C  C   . LEU A 1 222 ? 230.536 198.603 264.072 1.00 99.97  ? 222 LEU A C   1 
ATOM   1636  O  O   . LEU A 1 222 ? 230.736 198.112 262.959 1.00 103.57 ? 222 LEU A O   1 
ATOM   1637  C  CB  . LEU A 1 222 ? 229.800 200.956 264.560 1.00 95.85  ? 222 LEU A CB  1 
ATOM   1638  C  CG  . LEU A 1 222 ? 229.958 202.217 265.415 1.00 99.57  ? 222 LEU A CG  1 
ATOM   1639  C  CD1 . LEU A 1 222 ? 230.333 201.842 266.838 1.00 105.16 ? 222 LEU A CD1 1 
ATOM   1640  C  CD2 . LEU A 1 222 ? 230.949 203.214 264.840 1.00 98.83  ? 222 LEU A CD2 1 
ATOM   1641  N  N   . LEU A 1 223 ? 229.913 197.950 265.046 1.00 97.98  ? 223 LEU A N   1 
ATOM   1642  C  CA  . LEU A 1 223 ? 229.515 196.555 264.931 1.00 99.29  ? 223 LEU A CA  1 
ATOM   1643  C  C   . LEU A 1 223 ? 228.006 196.424 265.050 1.00 97.86  ? 223 LEU A C   1 
ATOM   1644  O  O   . LEU A 1 223 ? 227.375 197.117 265.852 1.00 94.69  ? 223 LEU A O   1 
ATOM   1645  C  CB  . LEU A 1 223 ? 230.190 195.698 266.007 1.00 104.77 ? 223 LEU A CB  1 
ATOM   1646  C  CG  . LEU A 1 223 ? 231.639 195.276 265.757 1.00 108.33 ? 223 LEU A CG  1 
ATOM   1647  C  CD1 . LEU A 1 223 ? 232.307 194.853 267.053 1.00 106.23 ? 223 LEU A CD1 1 
ATOM   1648  C  CD2 . LEU A 1 223 ? 231.682 194.150 264.740 1.00 105.55 ? 223 LEU A CD2 1 
ATOM   1649  N  N   . THR A 1 224 ? 227.439 195.520 264.256 1.00 101.47 ? 224 THR A N   1 
ATOM   1650  C  CA  . THR A 1 224 ? 226.016 195.226 264.283 1.00 101.71 ? 224 THR A CA  1 
ATOM   1651  C  C   . THR A 1 224 ? 225.764 193.922 265.036 1.00 96.33  ? 224 THR A C   1 
ATOM   1652  O  O   . THR A 1 224 ? 226.680 193.284 265.560 1.00 96.07  ? 224 THR A O   1 
ATOM   1653  C  CB  . THR A 1 224 ? 225.453 195.138 262.864 1.00 100.48 ? 224 THR A CB  1 
ATOM   1654  O  OG1 . THR A 1 224 ? 225.627 193.806 262.365 1.00 100.36 ? 224 THR A OG1 1 
ATOM   1655  C  CG2 . THR A 1 224 ? 226.172 196.114 261.945 1.00 101.44 ? 224 THR A CG2 1 
ATOM   1656  N  N   . ARG A 1 225 ? 224.495 193.516 265.079 1.00 89.50  ? 225 ARG A N   1 
ATOM   1657  C  CA  . ARG A 1 225 ? 224.144 192.266 265.736 1.00 89.74  ? 225 ARG A CA  1 
ATOM   1658  C  C   . ARG A 1 225 ? 224.596 191.058 264.935 1.00 93.35  ? 225 ARG A C   1 
ATOM   1659  O  O   . ARG A 1 225 ? 224.581 189.940 265.459 1.00 97.91  ? 225 ARG A O   1 
ATOM   1660  C  CB  . ARG A 1 225 ? 222.637 192.208 265.976 1.00 87.55  ? 225 ARG A CB  1 
ATOM   1661  C  CG  . ARG A 1 225 ? 222.015 193.557 266.279 1.00 80.75  ? 225 ARG A CG  1 
ATOM   1662  C  CD  . ARG A 1 225 ? 222.244 193.986 267.716 1.00 77.89  ? 225 ARG A CD  1 
ATOM   1663  N  NE  . ARG A 1 225 ? 223.606 194.450 267.944 1.00 79.90  ? 225 ARG A NE  1 
ATOM   1664  C  CZ  . ARG A 1 225 ? 224.094 195.600 267.505 1.00 83.78  ? 225 ARG A CZ  1 
ATOM   1665  N  NH1 . ARG A 1 225 ? 223.349 196.451 266.822 1.00 83.87  ? 225 ARG A NH1 1 
ATOM   1666  N  NH2 . ARG A 1 225 ? 225.363 195.903 267.756 1.00 87.07  ? 225 ARG A NH2 1 
ATOM   1667  N  N   . THR A 1 226 ? 224.995 191.256 263.683 1.00 96.89  ? 226 THR A N   1 
ATOM   1668  C  CA  . THR A 1 226 ? 225.498 190.184 262.840 1.00 106.34 ? 226 THR A CA  1 
ATOM   1669  C  C   . THR A 1 226 ? 227.017 190.080 262.871 1.00 108.12 ? 226 THR A C   1 
ATOM   1670  O  O   . THR A 1 226 ? 227.588 189.293 262.109 1.00 112.62 ? 226 THR A O   1 
ATOM   1671  C  CB  . THR A 1 226 ? 225.024 190.378 261.398 1.00 107.58 ? 226 THR A CB  1 
ATOM   1672  O  OG1 . THR A 1 226 ? 225.319 191.714 260.972 1.00 104.08 ? 226 THR A OG1 1 
ATOM   1673  C  CG2 . THR A 1 226 ? 223.526 190.136 261.293 1.00 106.40 ? 226 THR A CG2 1 
ATOM   1674  N  N   . GLY A 1 227 ? 227.677 190.850 263.729 1.00 105.37 ? 227 GLY A N   1 
ATOM   1675  C  CA  . GLY A 1 227 ? 229.128 190.838 263.785 1.00 107.50 ? 227 GLY A CA  1 
ATOM   1676  C  C   . GLY A 1 227 ? 229.788 191.374 262.534 1.00 108.97 ? 227 GLY A C   1 
ATOM   1677  O  O   . GLY A 1 227 ? 230.772 190.793 262.059 1.00 109.03 ? 227 GLY A O   1 
ATOM   1678  N  N   . GLU A 1 228 ? 229.271 192.471 261.987 1.00 106.35 ? 228 GLU A N   1 
ATOM   1679  C  CA  . GLU A 1 228 ? 229.788 193.060 260.760 1.00 105.30 ? 228 GLU A CA  1 
ATOM   1680  C  C   . GLU A 1 228 ? 230.308 194.454 261.075 1.00 103.48 ? 228 GLU A C   1 
ATOM   1681  O  O   . GLU A 1 228 ? 229.620 195.241 261.733 1.00 98.96  ? 228 GLU A O   1 
ATOM   1682  C  CB  . GLU A 1 228 ? 228.699 193.106 259.682 1.00 107.52 ? 228 GLU A CB  1 
ATOM   1683  C  CG  . GLU A 1 228 ? 228.717 194.311 258.744 1.00 111.47 ? 228 GLU A CG  1 
ATOM   1684  C  CD  . GLU A 1 228 ? 229.978 194.406 257.896 1.00 112.43 ? 228 GLU A CD  1 
ATOM   1685  O  OE1 . GLU A 1 228 ? 230.757 193.429 257.851 1.00 112.81 ? 228 GLU A OE1 1 
ATOM   1686  O  OE2 . GLU A 1 228 ? 230.179 195.457 257.253 1.00 110.96 ? 228 GLU A OE2 1 
ATOM   1687  N  N   . LYS A 1 229 ? 231.524 194.746 260.621 1.00 107.43 ? 229 LYS A N   1 
ATOM   1688  C  CA  . LYS A 1 229 ? 232.169 196.028 260.877 1.00 106.19 ? 229 LYS A CA  1 
ATOM   1689  C  C   . LYS A 1 229 ? 231.832 196.997 259.751 1.00 108.56 ? 229 LYS A C   1 
ATOM   1690  O  O   . LYS A 1 229 ? 232.188 196.756 258.593 1.00 108.05 ? 229 LYS A O   1 
ATOM   1691  C  CB  . LYS A 1 229 ? 233.682 195.852 260.994 1.00 105.04 ? 229 LYS A CB  1 
ATOM   1692  C  CG  . LYS A 1 229 ? 234.145 195.229 262.299 1.00 108.22 ? 229 LYS A CG  1 
ATOM   1693  C  CD  . LYS A 1 229 ? 235.459 194.484 262.116 1.00 109.87 ? 229 LYS A CD  1 
ATOM   1694  C  CE  . LYS A 1 229 ? 236.553 195.411 261.611 1.00 110.26 ? 229 LYS A CE  1 
ATOM   1695  N  NZ  . LYS A 1 229 ? 237.846 194.697 261.418 1.00 110.06 ? 229 LYS A NZ  1 
ATOM   1696  N  N   . ILE A 1 230 ? 231.171 198.100 260.094 1.00 111.33 ? 230 ILE A N   1 
ATOM   1697  C  CA  . ILE A 1 230 ? 230.668 199.062 259.118 1.00 106.38 ? 230 ILE A CA  1 
ATOM   1698  C  C   . ILE A 1 230 ? 231.290 200.423 259.392 1.00 99.91  ? 230 ILE A C   1 
ATOM   1699  O  O   . ILE A 1 230 ? 231.373 200.854 260.549 1.00 99.95  ? 230 ILE A O   1 
ATOM   1700  C  CB  . ILE A 1 230 ? 229.131 199.158 259.151 1.00 102.60 ? 230 ILE A CB  1 
ATOM   1701  C  CG1 . ILE A 1 230 ? 228.628 199.226 260.590 1.00 101.04 ? 230 ILE A CG1 1 
ATOM   1702  C  CG2 . ILE A 1 230 ? 228.506 197.982 258.422 1.00 98.12  ? 230 ILE A CG2 1 
ATOM   1703  C  CD1 . ILE A 1 230 ? 227.145 199.459 260.696 1.00 92.60  ? 230 ILE A CD1 1 
ATOM   1704  N  N   . TRP A 1 231 ? 231.738 201.085 258.329 1.00 94.93  ? 231 TRP A N   1 
ATOM   1705  C  CA  . TRP A 1 231 ? 232.153 202.476 258.421 1.00 96.57  ? 231 TRP A CA  1 
ATOM   1706  C  C   . TRP A 1 231 ? 230.933 203.364 258.630 1.00 89.33  ? 231 TRP A C   1 
ATOM   1707  O  O   . TRP A 1 231 ? 229.940 203.244 257.908 1.00 88.17  ? 231 TRP A O   1 
ATOM   1708  C  CB  . TRP A 1 231 ? 232.882 202.896 257.146 1.00 100.55 ? 231 TRP A CB  1 
ATOM   1709  C  CG  . TRP A 1 231 ? 234.332 202.530 257.078 1.00 105.20 ? 231 TRP A CG  1 
ATOM   1710  C  CD1 . TRP A 1 231 ? 234.862 201.381 256.570 1.00 103.50 ? 231 TRP A CD1 1 
ATOM   1711  C  CD2 . TRP A 1 231 ? 235.441 203.327 257.510 1.00 105.95 ? 231 TRP A CD2 1 
ATOM   1712  N  NE1 . TRP A 1 231 ? 236.231 201.408 256.669 1.00 103.07 ? 231 TRP A NE1 1 
ATOM   1713  C  CE2 . TRP A 1 231 ? 236.611 202.593 257.242 1.00 105.84 ? 231 TRP A CE2 1 
ATOM   1714  C  CE3 . TRP A 1 231 ? 235.557 204.584 258.109 1.00 102.67 ? 231 TRP A CE3 1 
ATOM   1715  C  CZ2 . TRP A 1 231 ? 237.880 203.073 257.552 1.00 107.92 ? 231 TRP A CZ2 1 
ATOM   1716  C  CZ3 . TRP A 1 231 ? 236.816 205.060 258.411 1.00 104.48 ? 231 TRP A CZ3 1 
ATOM   1717  C  CH2 . TRP A 1 231 ? 237.960 204.307 258.133 1.00 108.71 ? 231 TRP A CH2 1 
ATOM   1718  N  N   . ILE A 1 232 ? 230.999 204.257 259.613 1.00 83.02  ? 232 ILE A N   1 
ATOM   1719  C  CA  . ILE A 1 232 ? 229.927 205.208 259.872 1.00 78.80  ? 232 ILE A CA  1 
ATOM   1720  C  C   . ILE A 1 232 ? 230.533 206.562 260.206 1.00 82.53  ? 232 ILE A C   1 
ATOM   1721  O  O   . ILE A 1 232 ? 231.440 206.655 261.038 1.00 91.79  ? 232 ILE A O   1 
ATOM   1722  C  CB  . ILE A 1 232 ? 229.006 204.743 261.014 1.00 80.87  ? 232 ILE A CB  1 
ATOM   1723  C  CG1 . ILE A 1 232 ? 228.332 203.415 260.654 1.00 83.55  ? 232 ILE A CG1 1 
ATOM   1724  C  CG2 . ILE A 1 232 ? 227.986 205.815 261.338 1.00 80.52  ? 232 ILE A CG2 1 
ATOM   1725  C  CD1 . ILE A 1 232 ? 226.982 203.200 261.305 1.00 78.02  ? 232 ILE A CD1 1 
ATOM   1726  N  N   . LYS A 1 233 ? 230.019 207.608 259.570 1.00 81.35  ? 233 LYS A N   1 
ATOM   1727  C  CA  . LYS A 1 233 ? 230.403 208.987 259.842 1.00 82.29  ? 233 LYS A CA  1 
ATOM   1728  C  C   . LYS A 1 233 ? 229.409 209.607 260.814 1.00 79.11  ? 233 LYS A C   1 
ATOM   1729  O  O   . LYS A 1 233 ? 228.228 209.740 260.489 1.00 79.85  ? 233 LYS A O   1 
ATOM   1730  C  CB  . LYS A 1 233 ? 230.434 209.799 258.550 1.00 81.44  ? 233 LYS A CB  1 
ATOM   1731  C  CG  . LYS A 1 233 ? 230.609 211.286 258.760 1.00 83.17  ? 233 LYS A CG  1 
ATOM   1732  C  CD  . LYS A 1 233 ? 231.471 211.894 257.677 1.00 86.01  ? 233 LYS A CD  1 
ATOM   1733  C  CE  . LYS A 1 233 ? 230.828 211.733 256.315 1.00 87.11  ? 233 LYS A CE  1 
ATOM   1734  N  NZ  . LYS A 1 233 ? 229.372 212.031 256.355 1.00 85.71  ? 233 LYS A NZ  1 
ATOM   1735  N  N   . ALA A 1 234 ? 229.886 210.004 261.987 1.00 79.31  ? 234 ALA A N   1 
ATOM   1736  C  CA  . ALA A 1 234 ? 229.041 210.677 262.960 1.00 74.40  ? 234 ALA A CA  1 
ATOM   1737  C  C   . ALA A 1 234 ? 229.108 212.180 262.749 1.00 71.41  ? 234 ALA A C   1 
ATOM   1738  O  O   . ALA A 1 234 ? 230.120 212.717 262.298 1.00 81.27  ? 234 ALA A O   1 
ATOM   1739  C  CB  . ALA A 1 234 ? 229.462 210.328 264.384 1.00 82.63  ? 234 ALA A CB  1 
ATOM   1740  N  N   . SER A 1 235 ? 228.015 212.861 263.066 1.00 65.10  ? 235 SER A N   1 
ATOM   1741  C  CA  . SER A 1 235 ? 227.891 214.281 262.766 1.00 73.82  ? 235 SER A CA  1 
ATOM   1742  C  C   . SER A 1 235 ? 227.351 215.032 263.966 1.00 74.84  ? 235 SER A C   1 
ATOM   1743  O  O   . SER A 1 235 ? 226.423 215.835 263.861 1.00 77.79  ? 235 SER A O   1 
ATOM   1744  C  CB  . SER A 1 235 ? 227.006 214.499 261.545 1.00 76.83  ? 235 SER A CB  1 
ATOM   1745  O  OG  . SER A 1 235 ? 227.688 214.153 260.353 1.00 80.10  ? 235 SER A OG  1 
ATOM   1746  N  N   . ILE A 1 236 ? 227.937 214.775 265.133 1.00 75.89  ? 236 ILE A N   1 
ATOM   1747  C  CA  . ILE A 1 236 ? 227.433 215.364 266.367 1.00 78.10  ? 236 ILE A CA  1 
ATOM   1748  C  C   . ILE A 1 236 ? 227.495 216.881 266.272 1.00 77.12  ? 236 ILE A C   1 
ATOM   1749  O  O   . ILE A 1 236 ? 228.551 217.464 266.000 1.00 84.37  ? 236 ILE A O   1 
ATOM   1750  C  CB  . ILE A 1 236 ? 228.208 214.833 267.575 1.00 81.96  ? 236 ILE A CB  1 
ATOM   1751  C  CG1 . ILE A 1 236 ? 227.754 215.538 268.849 1.00 80.38  ? 236 ILE A CG1 1 
ATOM   1752  C  CG2 . ILE A 1 236 ? 229.705 214.959 267.364 1.00 89.78  ? 236 ILE A CG2 1 
ATOM   1753  C  CD1 . ILE A 1 236 ? 227.727 214.624 270.041 1.00 86.24  ? 236 ILE A CD1 1 
ATOM   1754  N  N   . SER A 1 237 ? 226.350 217.524 266.462 1.00 71.97  ? 237 SER A N   1 
ATOM   1755  C  CA  . SER A 1 237 ? 226.216 218.973 266.368 1.00 76.30  ? 237 SER A CA  1 
ATOM   1756  C  C   . SER A 1 237 ? 225.344 219.434 267.525 1.00 75.40  ? 237 SER A C   1 
ATOM   1757  O  O   . SER A 1 237 ? 224.133 219.625 267.365 1.00 77.71  ? 237 SER A O   1 
ATOM   1758  C  CB  . SER A 1 237 ? 225.613 219.381 265.025 1.00 82.11  ? 237 SER A CB  1 
ATOM   1759  O  OG  . SER A 1 237 ? 226.076 218.535 263.989 1.00 83.39  ? 237 SER A OG  1 
ATOM   1760  N  N   . PRO A 1 238 ? 225.927 219.629 268.701 1.00 80.19  ? 238 PRO A N   1 
ATOM   1761  C  CA  . PRO A 1 238 ? 225.118 219.941 269.880 1.00 85.50  ? 238 PRO A CA  1 
ATOM   1762  C  C   . PRO A 1 238 ? 224.379 221.255 269.712 1.00 86.85  ? 238 PRO A C   1 
ATOM   1763  O  O   . PRO A 1 238 ? 224.825 222.160 269.005 1.00 88.10  ? 238 PRO A O   1 
ATOM   1764  C  CB  . PRO A 1 238 ? 226.149 220.028 271.011 1.00 89.94  ? 238 PRO A CB  1 
ATOM   1765  C  CG  . PRO A 1 238 ? 227.388 219.392 270.471 1.00 91.93  ? 238 PRO A CG  1 
ATOM   1766  C  CD  . PRO A 1 238 ? 227.364 219.619 269.001 1.00 89.22  ? 238 PRO A CD  1 
ATOM   1767  N  N   . VAL A 1 239 ? 223.236 221.343 270.354 1.00 86.91  ? 239 VAL A N   1 
ATOM   1768  C  CA  . VAL A 1 239 ? 222.425 222.549 270.316 1.00 92.82  ? 239 VAL A CA  1 
ATOM   1769  C  C   . VAL A 1 239 ? 222.832 223.448 271.471 1.00 104.55 ? 239 VAL A C   1 
ATOM   1770  O  O   . VAL A 1 239 ? 223.298 222.986 272.517 1.00 107.73 ? 239 VAL A O   1 
ATOM   1771  C  CB  . VAL A 1 239 ? 220.922 222.207 270.360 1.00 91.78  ? 239 VAL A CB  1 
ATOM   1772  C  CG1 . VAL A 1 239 ? 220.458 222.006 271.787 1.00 96.15  ? 239 VAL A CG1 1 
ATOM   1773  C  CG2 . VAL A 1 239 ? 220.116 223.299 269.683 1.00 98.28  ? 239 VAL A CG2 1 
ATOM   1774  N  N   . TYR A 1 240 ? 222.682 224.755 271.266 1.00 110.29 ? 240 TYR A N   1 
ATOM   1775  C  CA  . TYR A 1 240 ? 222.939 225.759 272.297 1.00 112.72 ? 240 TYR A CA  1 
ATOM   1776  C  C   . TYR A 1 240 ? 221.677 226.608 272.401 1.00 115.53 ? 240 TYR A C   1 
ATOM   1777  O  O   . TYR A 1 240 ? 221.329 227.332 271.463 1.00 117.51 ? 240 TYR A O   1 
ATOM   1778  C  CB  . TYR A 1 240 ? 224.157 226.616 271.962 1.00 112.36 ? 240 TYR A CB  1 
ATOM   1779  C  CG  . TYR A 1 240 ? 225.391 225.834 271.570 1.00 107.13 ? 240 TYR A CG  1 
ATOM   1780  C  CD1 . TYR A 1 240 ? 226.197 225.238 272.530 1.00 102.28 ? 240 TYR A CD1 1 
ATOM   1781  C  CD2 . TYR A 1 240 ? 225.755 225.701 270.236 1.00 105.71 ? 240 TYR A CD2 1 
ATOM   1782  C  CE1 . TYR A 1 240 ? 227.326 224.529 272.171 1.00 100.11 ? 240 TYR A CE1 1 
ATOM   1783  C  CE2 . TYR A 1 240 ? 226.884 224.992 269.870 1.00 101.30 ? 240 TYR A CE2 1 
ATOM   1784  C  CZ  . TYR A 1 240 ? 227.664 224.408 270.842 1.00 98.64  ? 240 TYR A CZ  1 
ATOM   1785  O  OH  . TYR A 1 240 ? 228.788 223.702 270.485 1.00 96.51  ? 240 TYR A OH  1 
ATOM   1786  N  N   . ASP A 1 241 ? 220.993 226.518 273.533 1.00 115.41 ? 241 ASP A N   1 
ATOM   1787  C  CA  . ASP A 1 241 ? 219.758 227.258 273.715 1.00 118.58 ? 241 ASP A CA  1 
ATOM   1788  C  C   . ASP A 1 241 ? 220.050 228.736 273.974 1.00 131.25 ? 241 ASP A C   1 
ATOM   1789  O  O   . ASP A 1 241 ? 221.202 229.175 274.026 1.00 135.82 ? 241 ASP A O   1 
ATOM   1790  C  CB  . ASP A 1 241 ? 218.959 226.656 274.861 1.00 115.73 ? 241 ASP A CB  1 
ATOM   1791  C  CG  . ASP A 1 241 ? 218.875 225.157 274.767 1.00 113.89 ? 241 ASP A CG  1 
ATOM   1792  O  OD1 . ASP A 1 241 ? 219.681 224.485 275.438 1.00 111.65 ? 241 ASP A OD1 1 
ATOM   1793  O  OD2 . ASP A 1 241 ? 218.010 224.650 274.024 1.00 115.70 ? 241 ASP A OD2 1 
ATOM   1794  N  N   . VAL A 1 242 ? 218.974 229.510 274.138 1.00 135.68 ? 242 VAL A N   1 
ATOM   1795  C  CA  . VAL A 1 242 ? 219.111 230.951 274.340 1.00 136.35 ? 242 VAL A CA  1 
ATOM   1796  C  C   . VAL A 1 242 ? 219.779 231.255 275.675 1.00 133.32 ? 242 VAL A C   1 
ATOM   1797  O  O   . VAL A 1 242 ? 220.474 232.269 275.814 1.00 129.93 ? 242 VAL A O   1 
ATOM   1798  C  CB  . VAL A 1 242 ? 217.734 231.639 274.217 1.00 133.07 ? 242 VAL A CB  1 
ATOM   1799  C  CG1 . VAL A 1 242 ? 216.795 231.184 275.328 1.00 134.50 ? 242 VAL A CG1 1 
ATOM   1800  C  CG2 . VAL A 1 242 ? 217.885 233.155 274.216 1.00 124.86 ? 242 VAL A CG2 1 
ATOM   1801  N  N   . LEU A 1 243 ? 219.599 230.387 276.667 1.00 134.48 ? 243 LEU A N   1 
ATOM   1802  C  CA  . LEU A 1 243 ? 220.174 230.589 277.990 1.00 135.03 ? 243 LEU A CA  1 
ATOM   1803  C  C   . LEU A 1 243 ? 221.569 229.997 278.128 1.00 137.39 ? 243 LEU A C   1 
ATOM   1804  O  O   . LEU A 1 243 ? 222.048 229.856 279.259 1.00 141.15 ? 243 LEU A O   1 
ATOM   1805  C  CB  . LEU A 1 243 ? 219.254 229.992 279.057 1.00 135.01 ? 243 LEU A CB  1 
ATOM   1806  C  CG  . LEU A 1 243 ? 217.766 230.320 278.925 1.00 134.87 ? 243 LEU A CG  1 
ATOM   1807  C  CD1 . LEU A 1 243 ? 216.944 229.481 279.891 1.00 131.76 ? 243 LEU A CD1 1 
ATOM   1808  C  CD2 . LEU A 1 243 ? 217.522 231.802 279.154 1.00 130.46 ? 243 LEU A CD2 1 
ATOM   1809  N  N   . ALA A 1 244 ? 222.218 229.645 277.015 1.00 135.87 ? 244 ALA A N   1 
ATOM   1810  C  CA  . ALA A 1 244 ? 223.521 228.987 277.028 1.00 139.13 ? 244 ALA A CA  1 
ATOM   1811  C  C   . ALA A 1 244 ? 223.458 227.704 277.845 1.00 144.48 ? 244 ALA A C   1 
ATOM   1812  O  O   . ALA A 1 244 ? 222.369 227.163 278.067 1.00 144.60 ? 244 ALA A O   1 
ATOM   1813  C  CB  . ALA A 1 244 ? 224.604 229.923 277.570 1.00 137.30 ? 244 ALA A CB  1 
ATOM   1814  N  N   . HIS A 1 245 ? 224.611 227.211 278.295 1.00 145.19 ? 245 HIS A N   1 
ATOM   1815  C  CA  . HIS A 1 245 ? 224.697 225.967 279.060 1.00 141.10 ? 245 HIS A CA  1 
ATOM   1816  C  C   . HIS A 1 245 ? 224.015 224.824 278.303 1.00 134.83 ? 245 HIS A C   1 
ATOM   1817  O  O   . HIS A 1 245 ? 222.980 224.293 278.708 1.00 133.59 ? 245 HIS A O   1 
ATOM   1818  C  CB  . HIS A 1 245 ? 224.099 226.147 280.459 1.00 143.65 ? 245 HIS A CB  1 
ATOM   1819  C  CG  . HIS A 1 245 ? 224.662 227.312 281.212 1.00 148.23 ? 245 HIS A CG  1 
ATOM   1820  N  ND1 . HIS A 1 245 ? 224.205 228.601 281.038 1.00 147.93 ? 245 HIS A ND1 1 
ATOM   1821  C  CD2 . HIS A 1 245 ? 225.645 227.383 282.140 1.00 151.67 ? 245 HIS A CD2 1 
ATOM   1822  C  CE1 . HIS A 1 245 ? 224.882 229.416 281.827 1.00 147.35 ? 245 HIS A CE1 1 
ATOM   1823  N  NE2 . HIS A 1 245 ? 225.761 228.702 282.507 1.00 150.67 ? 245 HIS A NE2 1 
ATOM   1824  N  N   . LEU A 1 246 ? 224.630 224.490 277.167 1.00 127.50 ? 246 LEU A N   1 
ATOM   1825  C  CA  . LEU A 1 246 ? 224.057 223.554 276.207 1.00 118.02 ? 246 LEU A CA  1 
ATOM   1826  C  C   . LEU A 1 246 ? 223.548 222.291 276.891 1.00 119.75 ? 246 LEU A C   1 
ATOM   1827  O  O   . LEU A 1 246 ? 224.172 221.770 277.818 1.00 121.03 ? 246 LEU A O   1 
ATOM   1828  C  CB  . LEU A 1 246 ? 225.106 223.198 275.155 1.00 110.40 ? 246 LEU A CB  1 
ATOM   1829  C  CG  . LEU A 1 246 ? 226.263 222.306 275.615 1.00 108.33 ? 246 LEU A CG  1 
ATOM   1830  C  CD1 . LEU A 1 246 ? 226.044 220.840 275.237 1.00 102.72 ? 246 LEU A CD1 1 
ATOM   1831  C  CD2 . LEU A 1 246 ? 227.591 222.814 275.095 1.00 104.21 ? 246 LEU A CD2 1 
ATOM   1832  N  N   . GLN A 1 247 ? 222.385 221.814 276.444 1.00 118.59 ? 247 GLN A N   1 
ATOM   1833  C  CA  . GLN A 1 247 ? 221.812 220.584 276.980 1.00 113.94 ? 247 GLN A CA  1 
ATOM   1834  C  C   . GLN A 1 247 ? 221.705 219.487 275.929 1.00 108.85 ? 247 GLN A C   1 
ATOM   1835  O  O   . GLN A 1 247 ? 222.308 218.425 276.100 1.00 108.75 ? 247 GLN A O   1 
ATOM   1836  C  CB  . GLN A 1 247 ? 220.441 220.871 277.612 1.00 113.14 ? 247 GLN A CB  1 
ATOM   1837  C  CG  . GLN A 1 247 ? 219.498 221.679 276.741 1.00 111.12 ? 247 GLN A CG  1 
ATOM   1838  C  CD  . GLN A 1 247 ? 218.144 221.892 277.383 1.00 105.88 ? 247 GLN A CD  1 
ATOM   1839  O  OE1 . GLN A 1 247 ? 217.190 221.171 277.097 1.00 103.32 ? 247 GLN A OE1 1 
ATOM   1840  N  NE2 . GLN A 1 247 ? 218.051 222.893 278.251 1.00 99.21  ? 247 GLN A NE2 1 
ATOM   1841  N  N   . ASN A 1 248 ? 220.995 219.708 274.830 1.00 105.43 ? 248 ASN A N   1 
ATOM   1842  C  CA  . ASN A 1 248 ? 220.698 218.626 273.906 1.00 98.87  ? 248 ASN A CA  1 
ATOM   1843  C  C   . ASN A 1 248 ? 221.757 218.524 272.817 1.00 95.48  ? 248 ASN A C   1 
ATOM   1844  O  O   . ASN A 1 248 ? 222.361 219.519 272.409 1.00 91.50  ? 248 ASN A O   1 
ATOM   1845  C  CB  . ASN A 1 248 ? 219.315 218.803 273.279 1.00 93.09  ? 248 ASN A CB  1 
ATOM   1846  C  CG  . ASN A 1 248 ? 218.235 218.076 274.049 1.00 87.17  ? 248 ASN A CG  1 
ATOM   1847  O  OD1 . ASN A 1 248 ? 217.191 218.639 274.368 1.00 84.41  ? 248 ASN A OD1 1 
ATOM   1848  N  ND2 . ASN A 1 248 ? 218.491 216.816 274.365 1.00 89.28  ? 248 ASN A ND2 1 
ATOM   1849  N  N   . LEU A 1 249 ? 221.978 217.298 272.354 1.00 91.51  ? 249 LEU A N   1 
ATOM   1850  C  CA  . LEU A 1 249 ? 222.910 217.027 271.273 1.00 87.11  ? 249 LEU A CA  1 
ATOM   1851  C  C   . LEU A 1 249 ? 222.195 216.238 270.188 1.00 84.50  ? 249 LEU A C   1 
ATOM   1852  O  O   . LEU A 1 249 ? 221.248 215.500 270.454 1.00 86.55  ? 249 LEU A O   1 
ATOM   1853  C  CB  . LEU A 1 249 ? 224.131 216.253 271.767 1.00 88.05  ? 249 LEU A CB  1 
ATOM   1854  C  CG  . LEU A 1 249 ? 224.978 217.010 272.789 1.00 98.49  ? 249 LEU A CG  1 
ATOM   1855  C  CD1 . LEU A 1 249 ? 224.562 216.672 274.210 1.00 103.26 ? 249 LEU A CD1 1 
ATOM   1856  C  CD2 . LEU A 1 249 ? 226.446 216.715 272.586 1.00 98.90  ? 249 LEU A CD2 1 
ATOM   1857  N  N   . VAL A 1 250 ? 222.645 216.411 268.948 1.00 78.16  ? 250 VAL A N   1 
ATOM   1858  C  CA  . VAL A 1 250 ? 222.036 215.732 267.817 1.00 69.58  ? 250 VAL A CA  1 
ATOM   1859  C  C   . VAL A 1 250 ? 223.113 215.020 267.020 1.00 67.95  ? 250 VAL A C   1 
ATOM   1860  O  O   . VAL A 1 250 ? 224.131 215.603 266.641 1.00 79.21  ? 250 VAL A O   1 
ATOM   1861  C  CB  . VAL A 1 250 ? 221.250 216.695 266.914 1.00 70.57  ? 250 VAL A CB  1 
ATOM   1862  C  CG1 . VAL A 1 250 ? 220.472 215.914 265.891 1.00 68.14  ? 250 VAL A CG1 1 
ATOM   1863  C  CG2 . VAL A 1 250 ? 220.310 217.524 267.752 1.00 71.85  ? 250 VAL A CG2 1 
ATOM   1864  N  N   . MET A 1 251 ? 222.878 213.738 266.768 1.00 58.88  ? 251 MET A N   1 
ATOM   1865  C  CA  . MET A 1 251 ? 223.816 212.924 266.017 1.00 60.65  ? 251 MET A CA  1 
ATOM   1866  C  C   . MET A 1 251 ? 223.170 212.534 264.704 1.00 64.65  ? 251 MET A C   1 
ATOM   1867  O  O   . MET A 1 251 ? 221.994 212.167 264.681 1.00 66.60  ? 251 MET A O   1 
ATOM   1868  C  CB  . MET A 1 251 ? 224.212 211.670 266.794 1.00 65.85  ? 251 MET A CB  1 
ATOM   1869  C  CG  . MET A 1 251 ? 224.652 211.936 268.212 1.00 77.14  ? 251 MET A CG  1 
ATOM   1870  S  SD  . MET A 1 251 ? 226.415 211.684 268.463 1.00 93.66  ? 251 MET A SD  1 
ATOM   1871  C  CE  . MET A 1 251 ? 226.417 209.990 269.036 1.00 88.79  ? 251 MET A CE  1 
ATOM   1872  N  N   . THR A 1 252 ? 223.933 212.613 263.618 1.00 69.47  ? 252 THR A N   1 
ATOM   1873  C  CA  . THR A 1 252 ? 223.446 212.237 262.291 1.00 65.53  ? 252 THR A CA  1 
ATOM   1874  C  C   . THR A 1 252 ? 224.452 211.267 261.671 1.00 62.76  ? 252 THR A C   1 
ATOM   1875  O  O   . THR A 1 252 ? 225.331 211.664 260.905 1.00 68.13  ? 252 THR A O   1 
ATOM   1876  C  CB  . THR A 1 252 ? 223.234 213.476 261.433 1.00 70.97  ? 252 THR A CB  1 
ATOM   1877  O  OG1 . THR A 1 252 ? 222.496 214.449 262.183 1.00 73.08  ? 252 THR A OG1 1 
ATOM   1878  C  CG2 . THR A 1 252 ? 222.442 213.128 260.199 1.00 66.64  ? 252 THR A CG2 1 
ATOM   1879  N  N   . PHE A 1 253 ? 224.310 209.988 261.999 1.00 57.76  ? 253 PHE A N   1 
ATOM   1880  C  CA  . PHE A 1 253 ? 225.173 208.972 261.420 1.00 61.25  ? 253 PHE A CA  1 
ATOM   1881  C  C   . PHE A 1 253 ? 224.924 208.861 259.926 1.00 63.80  ? 253 PHE A C   1 
ATOM   1882  O  O   . PHE A 1 253 ? 223.802 209.038 259.455 1.00 66.42  ? 253 PHE A O   1 
ATOM   1883  C  CB  . PHE A 1 253 ? 224.919 207.615 262.070 1.00 62.97  ? 253 PHE A CB  1 
ATOM   1884  C  CG  . PHE A 1 253 ? 225.127 207.594 263.545 1.00 65.01  ? 253 PHE A CG  1 
ATOM   1885  C  CD1 . PHE A 1 253 ? 226.383 207.391 264.070 1.00 73.89  ? 253 PHE A CD1 1 
ATOM   1886  C  CD2 . PHE A 1 253 ? 224.067 207.771 264.406 1.00 67.80  ? 253 PHE A CD2 1 
ATOM   1887  C  CE1 . PHE A 1 253 ? 226.581 207.366 265.430 1.00 83.12  ? 253 PHE A CE1 1 
ATOM   1888  C  CE2 . PHE A 1 253 ? 224.255 207.748 265.765 1.00 76.45  ? 253 PHE A CE2 1 
ATOM   1889  C  CZ  . PHE A 1 253 ? 225.514 207.546 266.280 1.00 82.11  ? 253 PHE A CZ  1 
ATOM   1890  N  N   . SER A 1 254 ? 225.976 208.556 259.180 1.00 66.99  ? 254 SER A N   1 
ATOM   1891  C  CA  . SER A 1 254 ? 225.873 208.290 257.755 1.00 68.65  ? 254 SER A CA  1 
ATOM   1892  C  C   . SER A 1 254 ? 226.715 207.074 257.421 1.00 71.43  ? 254 SER A C   1 
ATOM   1893  O  O   . SER A 1 254 ? 227.654 206.741 258.144 1.00 78.95  ? 254 SER A O   1 
ATOM   1894  C  CB  . SER A 1 254 ? 226.335 209.484 256.917 1.00 73.51  ? 254 SER A CB  1 
ATOM   1895  O  OG  . SER A 1 254 ? 226.448 209.126 255.551 1.00 73.93  ? 254 SER A OG  1 
ATOM   1896  N  N   . ASP A 1 255 ? 226.379 206.415 256.322 1.00 67.62  ? 255 ASP A N   1 
ATOM   1897  C  CA  . ASP A 1 255 ? 227.116 205.245 255.868 1.00 71.72  ? 255 ASP A CA  1 
ATOM   1898  C  C   . ASP A 1 255 ? 228.012 205.658 254.710 1.00 79.50  ? 255 ASP A C   1 
ATOM   1899  O  O   . ASP A 1 255 ? 227.522 206.117 253.674 1.00 83.18  ? 255 ASP A O   1 
ATOM   1900  C  CB  . ASP A 1 255 ? 226.160 204.129 255.456 1.00 73.21  ? 255 ASP A CB  1 
ATOM   1901  C  CG  . ASP A 1 255 ? 226.878 202.848 255.074 1.00 77.13  ? 255 ASP A CG  1 
ATOM   1902  O  OD1 . ASP A 1 255 ? 226.305 201.766 255.312 1.00 80.21  ? 255 ASP A OD1 1 
ATOM   1903  O  OD2 . ASP A 1 255 ? 228.003 202.906 254.536 1.00 77.48  ? 255 ASP A OD2 1 
ATOM   1904  N  N   . ILE A 1 256 ? 229.319 205.489 254.885 1.00 82.54  ? 256 ILE A N   1 
ATOM   1905  C  CA  . ILE A 1 256 ? 230.292 205.872 253.874 1.00 85.21  ? 256 ILE A CA  1 
ATOM   1906  C  C   . ILE A 1 256 ? 230.822 204.655 253.116 1.00 82.97  ? 256 ILE A C   1 
ATOM   1907  O  O   . ILE A 1 256 ? 231.909 204.705 252.549 1.00 85.74  ? 256 ILE A O   1 
ATOM   1908  C  CB  . ILE A 1 256 ? 231.439 206.698 254.475 1.00 84.01  ? 256 ILE A CB  1 
ATOM   1909  C  CG1 . ILE A 1 256 ? 232.161 205.901 255.554 1.00 84.05  ? 256 ILE A CG1 1 
ATOM   1910  C  CG2 . ILE A 1 256 ? 230.909 208.004 255.046 1.00 82.75  ? 256 ILE A CG2 1 
ATOM   1911  C  CD1 . ILE A 1 256 ? 233.397 206.575 256.068 1.00 86.43  ? 256 ILE A CD1 1 
ATOM   1912  N  N   . THR A 1 257 ? 230.078 203.553 253.126 1.00 77.99  ? 257 THR A N   1 
ATOM   1913  C  CA  . THR A 1 257 ? 230.331 202.439 252.231 1.00 78.73  ? 257 THR A CA  1 
ATOM   1914  C  C   . THR A 1 257 ? 229.201 202.208 251.243 1.00 81.21  ? 257 THR A C   1 
ATOM   1915  O  O   . THR A 1 257 ? 229.431 201.588 250.201 1.00 83.13  ? 257 THR A O   1 
ATOM   1916  C  CB  . THR A 1 257 ? 230.563 201.146 253.023 1.00 81.71  ? 257 THR A CB  1 
ATOM   1917  O  OG1 . THR A 1 257 ? 229.344 200.752 253.664 1.00 84.26  ? 257 THR A OG1 1 
ATOM   1918  C  CG2 . THR A 1 257 ? 231.642 201.349 254.069 1.00 84.59  ? 257 THR A CG2 1 
ATOM   1919  N  N   . GLU A 1 258 ? 227.993 202.683 251.547 1.00 80.04  ? 258 GLU A N   1 
ATOM   1920  C  CA  . GLU A 1 258 ? 226.884 202.544 250.612 1.00 77.38  ? 258 GLU A CA  1 
ATOM   1921  C  C   . GLU A 1 258 ? 227.055 203.461 249.409 1.00 78.34  ? 258 GLU A C   1 
ATOM   1922  O  O   . GLU A 1 258 ? 226.703 203.088 248.283 1.00 79.54  ? 258 GLU A O   1 
ATOM   1923  C  CB  . GLU A 1 258 ? 225.564 202.838 251.319 1.00 74.38  ? 258 GLU A CB  1 
ATOM   1924  C  CG  . GLU A 1 258 ? 225.010 201.678 252.107 1.00 73.22  ? 258 GLU A CG  1 
ATOM   1925  C  CD  . GLU A 1 258 ? 223.657 201.992 252.707 1.00 73.77  ? 258 GLU A CD  1 
ATOM   1926  O  OE1 . GLU A 1 258 ? 223.090 203.050 252.364 1.00 74.12  ? 258 GLU A OE1 1 
ATOM   1927  O  OE2 . GLU A 1 258 ? 223.160 201.183 253.519 1.00 73.00  ? 258 GLU A OE2 1 
ATOM   1928  N  N   . GLU A 1 259 ? 227.573 204.670 249.627 1.00 78.07  ? 259 GLU A N   1 
ATOM   1929  C  CA  . GLU A 1 259 ? 227.716 205.614 248.525 1.00 79.26  ? 259 GLU A CA  1 
ATOM   1930  C  C   . GLU A 1 259 ? 228.712 205.109 247.493 1.00 76.29  ? 259 GLU A C   1 
ATOM   1931  O  O   . GLU A 1 259 ? 228.504 205.269 246.283 1.00 75.20  ? 259 GLU A O   1 
ATOM   1932  C  CB  . GLU A 1 259 ? 228.131 206.984 249.059 1.00 80.51  ? 259 GLU A CB  1 
ATOM   1933  C  CG  . GLU A 1 259 ? 227.304 207.512 250.234 1.00 81.41  ? 259 GLU A CG  1 
ATOM   1934  C  CD  . GLU A 1 259 ? 225.813 207.197 250.153 1.00 84.83  ? 259 GLU A CD  1 
ATOM   1935  O  OE1 . GLU A 1 259 ? 225.247 207.146 249.039 1.00 86.00  ? 259 GLU A OE1 1 
ATOM   1936  O  OE2 . GLU A 1 259 ? 225.201 206.995 251.222 1.00 81.62  ? 259 GLU A OE2 1 
ATOM   1937  N  N   . ARG A 1 260 ? 229.796 204.492 247.951 1.00 75.56  ? 260 ARG A N   1 
ATOM   1938  C  CA  . ARG A 1 260 ? 230.754 203.914 247.023 1.00 76.05  ? 260 ARG A CA  1 
ATOM   1939  C  C   . ARG A 1 260 ? 230.111 202.803 246.209 1.00 73.31  ? 260 ARG A C   1 
ATOM   1940  O  O   . ARG A 1 260 ? 230.384 202.661 245.013 1.00 80.34  ? 260 ARG A O   1 
ATOM   1941  C  CB  . ARG A 1 260 ? 231.974 203.405 247.786 1.00 80.21  ? 260 ARG A CB  1 
ATOM   1942  C  CG  . ARG A 1 260 ? 232.977 204.499 248.122 1.00 81.34  ? 260 ARG A CG  1 
ATOM   1943  C  CD  . ARG A 1 260 ? 232.561 205.261 249.374 1.00 84.85  ? 260 ARG A CD  1 
ATOM   1944  N  NE  . ARG A 1 260 ? 233.701 205.712 250.162 1.00 95.85  ? 260 ARG A NE  1 
ATOM   1945  C  CZ  . ARG A 1 260 ? 233.671 206.739 251.001 1.00 96.95  ? 260 ARG A CZ  1 
ATOM   1946  N  NH1 . ARG A 1 260 ? 232.567 207.440 251.195 1.00 94.67  ? 260 ARG A NH1 1 
ATOM   1947  N  NH2 . ARG A 1 260 ? 234.777 207.069 251.662 1.00 94.47  ? 260 ARG A NH2 1 
ATOM   1948  N  N   . GLN A 1 261 ? 229.232 202.019 246.833 1.00 70.16  ? 261 GLN A N   1 
ATOM   1949  C  CA  . GLN A 1 261 ? 228.538 200.966 246.103 1.00 77.07  ? 261 GLN A CA  1 
ATOM   1950  C  C   . GLN A 1 261 ? 227.567 201.537 245.076 1.00 77.93  ? 261 GLN A C   1 
ATOM   1951  O  O   . GLN A 1 261 ? 227.433 200.991 243.976 1.00 78.01  ? 261 GLN A O   1 
ATOM   1952  C  CB  . GLN A 1 261 ? 227.814 200.040 247.075 1.00 79.32  ? 261 GLN A CB  1 
ATOM   1953  C  CG  . GLN A 1 261 ? 228.729 199.026 247.732 1.00 86.32  ? 261 GLN A CG  1 
ATOM   1954  C  CD  . GLN A 1 261 ? 227.969 197.911 248.417 1.00 93.14  ? 261 GLN A CD  1 
ATOM   1955  O  OE1 . GLN A 1 261 ? 226.739 197.903 248.435 1.00 93.62  ? 261 GLN A OE1 1 
ATOM   1956  N  NE2 . GLN A 1 261 ? 228.700 196.960 248.984 1.00 93.57  ? 261 GLN A NE2 1 
ATOM   1957  N  N   . ILE A 1 262 ? 226.870 202.625 245.414 1.00 76.02  ? 262 ILE A N   1 
ATOM   1958  C  CA  . ILE A 1 262 ? 225.981 203.259 244.439 1.00 71.09  ? 262 ILE A CA  1 
ATOM   1959  C  C   . ILE A 1 262 ? 226.773 203.778 243.249 1.00 69.86  ? 262 ILE A C   1 
ATOM   1960  O  O   . ILE A 1 262 ? 226.379 203.596 242.091 1.00 70.74  ? 262 ILE A O   1 
ATOM   1961  C  CB  . ILE A 1 262 ? 225.162 204.378 245.094 1.00 63.33  ? 262 ILE A CB  1 
ATOM   1962  C  CG1 . ILE A 1 262 ? 224.100 203.777 245.992 1.00 59.52  ? 262 ILE A CG1 1 
ATOM   1963  C  CG2 . ILE A 1 262 ? 224.541 205.267 244.036 1.00 61.37  ? 262 ILE A CG2 1 
ATOM   1964  C  CD1 . ILE A 1 262 ? 222.959 203.224 245.219 1.00 58.57  ? 262 ILE A CD1 1 
ATOM   1965  N  N   . ARG A 1 263 ? 227.898 204.437 243.513 1.00 68.95  ? 263 ARG A N   1 
ATOM   1966  C  CA  . ARG A 1 263 ? 228.721 204.917 242.411 1.00 72.32  ? 263 ARG A CA  1 
ATOM   1967  C  C   . ARG A 1 263 ? 229.243 203.755 241.576 1.00 73.43  ? 263 ARG A C   1 
ATOM   1968  O  O   . ARG A 1 263 ? 229.315 203.847 240.343 1.00 78.58  ? 263 ARG A O   1 
ATOM   1969  C  CB  . ARG A 1 263 ? 229.876 205.761 242.945 1.00 78.17  ? 263 ARG A CB  1 
ATOM   1970  C  CG  . ARG A 1 263 ? 229.594 207.253 242.954 1.00 87.53  ? 263 ARG A CG  1 
ATOM   1971  C  CD  . ARG A 1 263 ? 229.781 207.852 241.572 1.00 96.40  ? 263 ARG A CD  1 
ATOM   1972  N  NE  . ARG A 1 263 ? 231.095 207.548 241.020 1.00 96.20  ? 263 ARG A NE  1 
ATOM   1973  C  CZ  . ARG A 1 263 ? 231.340 207.367 239.730 1.00 92.18  ? 263 ARG A CZ  1 
ATOM   1974  N  NH1 . ARG A 1 263 ? 230.379 207.450 238.825 1.00 89.23  ? 263 ARG A NH1 1 
ATOM   1975  N  NH2 . ARG A 1 263 ? 232.582 207.095 239.338 1.00 90.81  ? 263 ARG A NH2 1 
ATOM   1976  N  N   . GLN A 1 264 ? 229.613 202.652 242.228 1.00 68.07  ? 264 GLN A N   1 
ATOM   1977  C  CA  . GLN A 1 264 ? 230.093 201.490 241.493 1.00 68.03  ? 264 GLN A CA  1 
ATOM   1978  C  C   . GLN A 1 264 ? 229.002 200.914 240.603 1.00 69.67  ? 264 GLN A C   1 
ATOM   1979  O  O   . GLN A 1 264 ? 229.263 200.532 239.454 1.00 77.82  ? 264 GLN A O   1 
ATOM   1980  C  CB  . GLN A 1 264 ? 230.608 200.434 242.467 1.00 72.88  ? 264 GLN A CB  1 
ATOM   1981  C  CG  . GLN A 1 264 ? 231.259 199.237 241.796 1.00 81.24  ? 264 GLN A CG  1 
ATOM   1982  C  CD  . GLN A 1 264 ? 231.802 198.234 242.793 1.00 91.39  ? 264 GLN A CD  1 
ATOM   1983  O  OE1 . GLN A 1 264 ? 231.448 198.258 243.972 1.00 94.98  ? 264 GLN A OE1 1 
ATOM   1984  N  NE2 . GLN A 1 264 ? 232.670 197.344 242.324 1.00 91.63  ? 264 GLN A NE2 1 
ATOM   1985  N  N   . LEU A 1 265 ? 227.774 200.837 241.117 1.00 62.71  ? 265 LEU A N   1 
ATOM   1986  C  CA  . LEU A 1 265 ? 226.667 200.348 240.305 1.00 64.47  ? 265 LEU A CA  1 
ATOM   1987  C  C   . LEU A 1 265 ? 226.421 201.266 239.121 1.00 69.88  ? 265 LEU A C   1 
ATOM   1988  O  O   . LEU A 1 265 ? 226.212 200.799 237.994 1.00 74.45  ? 265 LEU A O   1 
ATOM   1989  C  CB  . LEU A 1 265 ? 225.408 200.216 241.152 1.00 59.78  ? 265 LEU A CB  1 
ATOM   1990  C  CG  . LEU A 1 265 ? 224.101 200.096 240.377 1.00 57.63  ? 265 LEU A CG  1 
ATOM   1991  C  CD1 . LEU A 1 265 ? 224.067 198.819 239.585 1.00 61.08  ? 265 LEU A CD1 1 
ATOM   1992  C  CD2 . LEU A 1 265 ? 222.936 200.148 241.333 1.00 60.01  ? 265 LEU A CD2 1 
ATOM   1993  N  N   . GLU A 1 266 ? 226.467 202.576 239.357 1.00 69.72  ? 266 GLU A N   1 
ATOM   1994  C  CA  . GLU A 1 266 ? 226.331 203.545 238.277 1.00 67.92  ? 266 GLU A CA  1 
ATOM   1995  C  C   . GLU A 1 266 ? 227.352 203.288 237.183 1.00 67.96  ? 266 GLU A C   1 
ATOM   1996  O  O   . GLU A 1 266 ? 227.005 203.177 236.001 1.00 69.54  ? 266 GLU A O   1 
ATOM   1997  C  CB  . GLU A 1 266 ? 226.506 204.954 238.837 1.00 71.24  ? 266 GLU A CB  1 
ATOM   1998  C  CG  . GLU A 1 266 ? 226.151 206.076 237.893 1.00 72.11  ? 266 GLU A CG  1 
ATOM   1999  C  CD  . GLU A 1 266 ? 224.668 206.292 237.775 1.00 74.54  ? 266 GLU A CD  1 
ATOM   2000  O  OE1 . GLU A 1 266 ? 223.906 205.448 238.269 1.00 70.75  ? 266 GLU A OE1 1 
ATOM   2001  O  OE2 . GLU A 1 266 ? 224.258 207.318 237.195 1.00 79.77  ? 266 GLU A OE2 1 
ATOM   2002  N  N   . GLY A 1 267 ? 228.622 203.174 237.566 1.00 72.50  ? 267 GLY A N   1 
ATOM   2003  C  CA  . GLY A 1 267 ? 229.667 202.998 236.573 1.00 77.13  ? 267 GLY A CA  1 
ATOM   2004  C  C   . GLY A 1 267 ? 229.546 201.692 235.813 1.00 73.21  ? 267 GLY A C   1 
ATOM   2005  O  O   . GLY A 1 267 ? 229.715 201.657 234.591 1.00 77.85  ? 267 GLY A O   1 
ATOM   2006  N  N   . ASN A 1 268 ? 229.259 200.601 236.522 1.00 68.76  ? 268 ASN A N   1 
ATOM   2007  C  CA  . ASN A 1 268 ? 229.171 199.308 235.860 1.00 67.40  ? 268 ASN A CA  1 
ATOM   2008  C  C   . ASN A 1 268 ? 228.002 199.269 234.890 1.00 66.55  ? 268 ASN A C   1 
ATOM   2009  O  O   . ASN A 1 268 ? 228.129 198.771 233.763 1.00 69.98  ? 268 ASN A O   1 
ATOM   2010  C  CB  . ASN A 1 268 ? 229.046 198.203 236.905 1.00 70.41  ? 268 ASN A CB  1 
ATOM   2011  C  CG  . ASN A 1 268 ? 230.310 198.029 237.716 1.00 75.37  ? 268 ASN A CG  1 
ATOM   2012  O  OD1 . ASN A 1 268 ? 231.222 198.850 237.642 1.00 76.70  ? 268 ASN A OD1 1 
ATOM   2013  N  ND2 . ASN A 1 268 ? 230.371 196.961 238.498 1.00 76.50  ? 268 ASN A ND2 1 
ATOM   2014  N  N   . ILE A 1 269 ? 226.858 199.810 235.296 1.00 64.23  ? 269 ILE A N   1 
ATOM   2015  C  CA  . ILE A 1 269 ? 225.693 199.783 234.427 1.00 65.99  ? 269 ILE A CA  1 
ATOM   2016  C  C   . ILE A 1 269 ? 225.876 200.733 233.249 1.00 73.80  ? 269 ILE A C   1 
ATOM   2017  O  O   . ILE A 1 269 ? 225.336 200.501 232.164 1.00 78.46  ? 269 ILE A O   1 
ATOM   2018  C  CB  . ILE A 1 269 ? 224.441 200.093 235.257 1.00 67.00  ? 269 ILE A CB  1 
ATOM   2019  C  CG1 . ILE A 1 269 ? 223.192 199.543 234.594 1.00 73.74  ? 269 ILE A CG1 1 
ATOM   2020  C  CG2 . ILE A 1 269 ? 224.306 201.581 235.488 1.00 68.80  ? 269 ILE A CG2 1 
ATOM   2021  C  CD1 . ILE A 1 269 ? 221.951 200.000 235.291 1.00 78.14  ? 269 ILE A CD1 1 
ATOM   2022  N  N   . LEU A 1 270 ? 226.666 201.799 233.421 1.00 75.37  ? 270 LEU A N   1 
ATOM   2023  C  CA  . LEU A 1 270 ? 226.978 202.657 232.280 1.00 70.83  ? 270 LEU A CA  1 
ATOM   2024  C  C   . LEU A 1 270 ? 227.930 201.975 231.310 1.00 72.03  ? 270 LEU A C   1 
ATOM   2025  O  O   . LEU A 1 270 ? 227.823 202.160 230.093 1.00 73.68  ? 270 LEU A O   1 
ATOM   2026  C  CB  . LEU A 1 270 ? 227.573 203.976 232.753 1.00 70.97  ? 270 LEU A CB  1 
ATOM   2027  C  CG  . LEU A 1 270 ? 226.570 205.116 232.809 1.00 70.01  ? 270 LEU A CG  1 
ATOM   2028  C  CD1 . LEU A 1 270 ? 227.195 206.342 233.445 1.00 75.33  ? 270 LEU A CD1 1 
ATOM   2029  C  CD2 . LEU A 1 270 ? 226.060 205.424 231.429 1.00 66.33  ? 270 LEU A CD2 1 
ATOM   2030  N  N   . ALA A 1 271 ? 228.893 201.214 231.826 1.00 73.13  ? 271 ALA A N   1 
ATOM   2031  C  CA  . ALA A 1 271 ? 229.749 200.433 230.941 1.00 73.31  ? 271 ALA A CA  1 
ATOM   2032  C  C   . ALA A 1 271 ? 228.931 199.406 230.175 1.00 72.21  ? 271 ALA A C   1 
ATOM   2033  O  O   . ALA A 1 271 ? 229.233 199.097 229.017 1.00 71.96  ? 271 ALA A O   1 
ATOM   2034  C  CB  . ALA A 1 271 ? 230.861 199.759 231.738 1.00 80.86  ? 271 ALA A CB  1 
ATOM   2035  N  N   . ALA A 1 272 ? 227.897 198.856 230.814 1.00 73.83  ? 272 ALA A N   1 
ATOM   2036  C  CA  . ALA A 1 272 ? 226.945 198.014 230.094 1.00 77.23  ? 272 ALA A CA  1 
ATOM   2037  C  C   . ALA A 1 272 ? 226.198 198.807 229.026 1.00 75.16  ? 272 ALA A C   1 
ATOM   2038  O  O   . ALA A 1 272 ? 225.990 198.318 227.911 1.00 74.71  ? 272 ALA A O   1 
ATOM   2039  C  CB  . ALA A 1 272 ? 225.961 197.383 231.074 1.00 71.56  ? 272 ALA A CB  1 
ATOM   2040  N  N   . MET A 1 273 ? 225.776 200.027 229.359 1.00 71.17  ? 273 MET A N   1 
ATOM   2041  C  CA  . MET A 1 273 ? 225.160 200.926 228.387 1.00 68.93  ? 273 MET A CA  1 
ATOM   2042  C  C   . MET A 1 273 ? 226.029 201.092 227.147 1.00 73.18  ? 273 MET A C   1 
ATOM   2043  O  O   . MET A 1 273 ? 225.544 201.009 226.014 1.00 72.99  ? 273 MET A O   1 
ATOM   2044  C  CB  . MET A 1 273 ? 224.933 202.291 229.036 1.00 72.42  ? 273 MET A CB  1 
ATOM   2045  C  CG  . MET A 1 273 ? 223.670 203.025 228.662 1.00 70.43  ? 273 MET A CG  1 
ATOM   2046  S  SD  . MET A 1 273 ? 222.138 202.210 229.053 1.00 61.54  ? 273 MET A SD  1 
ATOM   2047  C  CE  . MET A 1 273 ? 221.308 202.414 227.492 1.00 56.52  ? 273 MET A CE  1 
ATOM   2048  N  N   . CYS A 1 274 ? 227.320 201.344 227.348 1.00 76.39  ? 274 CYS A N   1 
ATOM   2049  C  CA  . CYS A 1 274 ? 228.158 201.844 226.263 1.00 77.73  ? 274 CYS A CA  1 
ATOM   2050  C  C   . CYS A 1 274 ? 228.505 200.783 225.226 1.00 78.10  ? 274 CYS A C   1 
ATOM   2051  O  O   . CYS A 1 274 ? 228.737 201.131 224.064 1.00 78.04  ? 274 CYS A O   1 
ATOM   2052  C  CB  . CYS A 1 274 ? 229.437 202.455 226.832 1.00 84.65  ? 274 CYS A CB  1 
ATOM   2053  S  SG  . CYS A 1 274 ? 229.208 204.130 227.464 1.00 92.23  ? 274 CYS A SG  1 
ATOM   2054  N  N   . SER A 1 275 ? 228.553 199.506 225.605 1.00 79.60  ? 275 SER A N   1 
ATOM   2055  C  CA  . SER A 1 275 ? 228.774 198.457 224.618 1.00 75.94  ? 275 SER A CA  1 
ATOM   2056  C  C   . SER A 1 275 ? 227.525 198.157 223.803 1.00 75.50  ? 275 SER A C   1 
ATOM   2057  O  O   . SER A 1 275 ? 227.618 197.453 222.792 1.00 71.91  ? 275 SER A O   1 
ATOM   2058  C  CB  . SER A 1 275 ? 229.264 197.179 225.302 1.00 77.12  ? 275 SER A CB  1 
ATOM   2059  O  OG  . SER A 1 275 ? 228.226 196.564 226.041 1.00 79.83  ? 275 SER A OG  1 
ATOM   2060  N  N   . SER A 1 276 ? 226.370 198.677 224.224 1.00 78.20  ? 276 SER A N   1 
ATOM   2061  C  CA  . SER A 1 276 ? 225.075 198.547 223.564 1.00 75.61  ? 276 SER A CA  1 
ATOM   2062  C  C   . SER A 1 276 ? 224.687 197.100 223.276 1.00 73.07  ? 276 SER A C   1 
ATOM   2063  O  O   . SER A 1 276 ? 224.571 196.721 222.104 1.00 71.41  ? 276 SER A O   1 
ATOM   2064  C  CB  . SER A 1 276 ? 225.071 199.345 222.261 1.00 73.29  ? 276 SER A CB  1 
ATOM   2065  O  OG  . SER A 1 276 ? 225.372 200.706 222.500 1.00 72.33  ? 276 SER A OG  1 
ATOM   2066  N  N   . PRO A 1 277 ? 224.472 196.267 224.290 1.00 72.45  ? 277 PRO A N   1 
ATOM   2067  C  CA  . PRO A 1 277 ? 223.885 194.956 224.045 1.00 67.32  ? 277 PRO A CA  1 
ATOM   2068  C  C   . PRO A 1 277 ? 222.434 195.098 223.632 1.00 64.33  ? 277 PRO A C   1 
ATOM   2069  O  O   . PRO A 1 277 ? 221.853 196.186 223.755 1.00 65.75  ? 277 PRO A O   1 
ATOM   2070  C  CB  . PRO A 1 277 ? 224.006 194.256 225.406 1.00 72.74  ? 277 PRO A CB  1 
ATOM   2071  C  CG  . PRO A 1 277 ? 225.121 194.935 226.079 1.00 75.48  ? 277 PRO A CG  1 
ATOM   2072  C  CD  . PRO A 1 277 ? 225.015 196.365 225.654 1.00 74.78  ? 277 PRO A CD  1 
ATOM   2073  N  N   . PRO A 1 278 ? 221.817 194.034 223.128 1.00 63.54  ? 278 PRO A N   1 
ATOM   2074  C  CA  . PRO A 1 278 ? 220.395 194.100 222.782 1.00 65.41  ? 278 PRO A CA  1 
ATOM   2075  C  C   . PRO A 1 278 ? 219.534 194.389 224.001 1.00 66.25  ? 278 PRO A C   1 
ATOM   2076  O  O   . PRO A 1 278 ? 220.008 194.497 225.135 1.00 69.56  ? 278 PRO A O   1 
ATOM   2077  C  CB  . PRO A 1 278 ? 220.103 192.712 222.209 1.00 64.70  ? 278 PRO A CB  1 
ATOM   2078  C  CG  . PRO A 1 278 ? 221.418 192.234 221.713 1.00 65.17  ? 278 PRO A CG  1 
ATOM   2079  C  CD  . PRO A 1 278 ? 222.440 192.787 222.658 1.00 66.31  ? 278 PRO A CD  1 
ATOM   2080  N  N   . PHE A 1 279 ? 218.233 194.510 223.747 1.00 61.14  ? 279 PHE A N   1 
ATOM   2081  C  CA  . PHE A 1 279 ? 217.300 194.908 224.793 1.00 59.90  ? 279 PHE A CA  1 
ATOM   2082  C  C   . PHE A 1 279 ? 217.292 193.904 225.940 1.00 67.39  ? 279 PHE A C   1 
ATOM   2083  O  O   . PHE A 1 279 ? 217.464 194.275 227.110 1.00 71.05  ? 279 PHE A O   1 
ATOM   2084  C  CB  . PHE A 1 279 ? 215.909 195.054 224.190 1.00 56.70  ? 279 PHE A CB  1 
ATOM   2085  C  CG  . PHE A 1 279 ? 215.032 196.011 224.915 1.00 58.14  ? 279 PHE A CG  1 
ATOM   2086  C  CD1 . PHE A 1 279 ? 215.537 197.198 225.394 1.00 65.83  ? 279 PHE A CD1 1 
ATOM   2087  C  CD2 . PHE A 1 279 ? 213.692 195.744 225.081 1.00 60.56  ? 279 PHE A CD2 1 
ATOM   2088  C  CE1 . PHE A 1 279 ? 214.725 198.091 226.050 1.00 71.05  ? 279 PHE A CE1 1 
ATOM   2089  C  CE2 . PHE A 1 279 ? 212.874 196.631 225.732 1.00 66.23  ? 279 PHE A CE2 1 
ATOM   2090  C  CZ  . PHE A 1 279 ? 213.390 197.807 226.219 1.00 72.25  ? 279 PHE A CZ  1 
ATOM   2091  N  N   . HIS A 1 280 ? 217.111 192.620 225.623 1.00 65.45  ? 280 HIS A N   1 
ATOM   2092  C  CA  . HIS A 1 280 ? 217.034 191.605 226.670 1.00 64.06  ? 280 HIS A CA  1 
ATOM   2093  C  C   . HIS A 1 280 ? 218.348 191.456 227.422 1.00 66.43  ? 280 HIS A C   1 
ATOM   2094  O  O   . HIS A 1 280 ? 218.344 191.338 228.656 1.00 74.85  ? 280 HIS A O   1 
ATOM   2095  C  CB  . HIS A 1 280 ? 216.616 190.263 226.081 1.00 63.52  ? 280 HIS A CB  1 
ATOM   2096  C  CG  . HIS A 1 280 ? 215.216 190.246 225.556 1.00 73.43  ? 280 HIS A CG  1 
ATOM   2097  N  ND1 . HIS A 1 280 ? 214.646 191.328 224.921 1.00 73.12  ? 280 HIS A ND1 1 
ATOM   2098  C  CD2 . HIS A 1 280 ? 214.272 189.277 225.567 1.00 80.67  ? 280 HIS A CD2 1 
ATOM   2099  C  CE1 . HIS A 1 280 ? 213.410 191.027 224.567 1.00 77.96  ? 280 HIS A CE1 1 
ATOM   2100  N  NE2 . HIS A 1 280 ? 213.159 189.787 224.946 1.00 85.03  ? 280 HIS A NE2 1 
ATOM   2101  N  N   . GLU A 1 281 ? 219.475 191.455 226.708 1.00 59.55  ? 281 GLU A N   1 
ATOM   2102  C  CA  . GLU A 1 281 ? 220.756 191.314 227.386 1.00 61.30  ? 281 GLU A CA  1 
ATOM   2103  C  C   . GLU A 1 281 ? 220.994 192.471 228.343 1.00 69.01  ? 281 GLU A C   1 
ATOM   2104  O  O   . GLU A 1 281 ? 221.520 192.280 229.447 1.00 72.22  ? 281 GLU A O   1 
ATOM   2105  C  CB  . GLU A 1 281 ? 221.886 191.221 226.370 1.00 63.94  ? 281 GLU A CB  1 
ATOM   2106  C  CG  . GLU A 1 281 ? 223.242 190.971 227.001 1.00 70.47  ? 281 GLU A CG  1 
ATOM   2107  C  CD  . GLU A 1 281 ? 224.203 190.265 226.065 1.00 81.94  ? 281 GLU A CD  1 
ATOM   2108  O  OE1 . GLU A 1 281 ? 223.933 190.232 224.846 1.00 84.21  ? 281 GLU A OE1 1 
ATOM   2109  O  OE2 . GLU A 1 281 ? 225.230 189.744 226.548 1.00 84.56  ? 281 GLU A OE2 1 
ATOM   2110  N  N   . MET A 1 282 ? 220.593 193.678 227.946 1.00 68.41  ? 282 MET A N   1 
ATOM   2111  C  CA  . MET A 1 282 ? 220.808 194.833 228.806 1.00 64.97  ? 282 MET A CA  1 
ATOM   2112  C  C   . MET A 1 282 ? 219.893 194.781 230.022 1.00 62.15  ? 282 MET A C   1 
ATOM   2113  O  O   . MET A 1 282 ? 220.322 195.087 231.135 1.00 63.20  ? 282 MET A O   1 
ATOM   2114  C  CB  . MET A 1 282 ? 220.597 196.115 228.006 1.00 65.46  ? 282 MET A CB  1 
ATOM   2115  C  CG  . MET A 1 282 ? 219.957 197.267 228.739 1.00 67.35  ? 282 MET A CG  1 
ATOM   2116  S  SD  . MET A 1 282 ? 220.999 197.752 230.125 1.00 93.41  ? 282 MET A SD  1 
ATOM   2117  C  CE  . MET A 1 282 ? 222.036 198.952 229.331 1.00 78.50  ? 282 MET A CE  1 
ATOM   2118  N  N   . GLY A 1 283 ? 218.631 194.408 229.837 1.00 63.39  ? 283 GLY A N   1 
ATOM   2119  C  CA  . GLY A 1 283 ? 217.773 194.248 230.998 1.00 69.28  ? 283 GLY A CA  1 
ATOM   2120  C  C   . GLY A 1 283 ? 218.341 193.241 231.978 1.00 71.64  ? 283 GLY A C   1 
ATOM   2121  O  O   . GLY A 1 283 ? 218.326 193.457 233.199 1.00 75.28  ? 283 GLY A O   1 
ATOM   2122  N  N   . GLU A 1 284 ? 218.878 192.140 231.454 1.00 67.57  ? 284 GLU A N   1 
ATOM   2123  C  CA  . GLU A 1 284 ? 219.525 191.160 232.309 1.00 65.45  ? 284 GLU A CA  1 
ATOM   2124  C  C   . GLU A 1 284 ? 220.718 191.759 233.039 1.00 65.09  ? 284 GLU A C   1 
ATOM   2125  O  O   . GLU A 1 284 ? 220.917 191.488 234.226 1.00 69.92  ? 284 GLU A O   1 
ATOM   2126  C  CB  . GLU A 1 284 ? 219.953 189.948 231.488 1.00 70.08  ? 284 GLU A CB  1 
ATOM   2127  C  CG  . GLU A 1 284 ? 220.319 188.743 232.330 1.00 76.76  ? 284 GLU A CG  1 
ATOM   2128  C  CD  . GLU A 1 284 ? 219.119 188.099 232.989 1.00 83.83  ? 284 GLU A CD  1 
ATOM   2129  O  OE1 . GLU A 1 284 ? 217.979 188.371 232.556 1.00 85.04  ? 284 GLU A OE1 1 
ATOM   2130  O  OE2 . GLU A 1 284 ? 219.316 187.320 233.944 1.00 87.40  ? 284 GLU A OE2 1 
ATOM   2131  N  N   . ILE A 1 285 ? 221.534 192.561 232.353 1.00 58.74  ? 285 ILE A N   1 
ATOM   2132  C  CA  . ILE A 1 285 ? 222.712 193.112 233.020 1.00 62.92  ? 285 ILE A CA  1 
ATOM   2133  C  C   . ILE A 1 285 ? 222.296 194.093 234.113 1.00 69.31  ? 285 ILE A C   1 
ATOM   2134  O  O   . ILE A 1 285 ? 222.896 194.126 235.196 1.00 71.78  ? 285 ILE A O   1 
ATOM   2135  C  CB  . ILE A 1 285 ? 223.684 193.738 231.994 1.00 60.15  ? 285 ILE A CB  1 
ATOM   2136  C  CG1 . ILE A 1 285 ? 225.095 193.834 232.568 1.00 55.08  ? 285 ILE A CG1 1 
ATOM   2137  C  CG2 . ILE A 1 285 ? 223.261 195.122 231.574 1.00 67.50  ? 285 ILE A CG2 1 
ATOM   2138  C  CD1 . ILE A 1 285 ? 225.735 192.521 232.834 1.00 54.32  ? 285 ILE A CD1 1 
ATOM   2139  N  N   . ILE A 1 286 ? 221.229 194.861 233.875 1.00 67.57  ? 286 ILE A N   1 
ATOM   2140  C  CA  . ILE A 1 286 ? 220.720 195.782 234.888 1.00 62.87  ? 286 ILE A CA  1 
ATOM   2141  C  C   . ILE A 1 286 ? 220.304 195.009 236.131 1.00 68.74  ? 286 ILE A C   1 
ATOM   2142  O  O   . ILE A 1 286 ? 220.715 195.327 237.258 1.00 74.49  ? 286 ILE A O   1 
ATOM   2143  C  CB  . ILE A 1 286 ? 219.536 196.590 234.330 1.00 60.81  ? 286 ILE A CB  1 
ATOM   2144  C  CG1 . ILE A 1 286 ? 220.015 197.804 233.553 1.00 65.22  ? 286 ILE A CG1 1 
ATOM   2145  C  CG2 . ILE A 1 286 ? 218.624 197.054 235.445 1.00 59.04  ? 286 ILE A CG2 1 
ATOM   2146  C  CD1 . ILE A 1 286 ? 218.901 198.518 232.819 1.00 66.80  ? 286 ILE A CD1 1 
ATOM   2147  N  N   . CYS A 1 287 ? 219.489 193.966 235.939 1.00 66.77  ? 287 CYS A N   1 
ATOM   2148  C  CA  . CYS A 1 287 ? 218.975 193.225 237.087 1.00 60.75  ? 287 CYS A CA  1 
ATOM   2149  C  C   . CYS A 1 287 ? 220.082 192.471 237.812 1.00 62.18  ? 287 CYS A C   1 
ATOM   2150  O  O   . CYS A 1 287 ? 220.081 192.403 239.045 1.00 66.65  ? 287 CYS A O   1 
ATOM   2151  C  CB  . CYS A 1 287 ? 217.869 192.279 236.650 1.00 65.38  ? 287 CYS A CB  1 
ATOM   2152  S  SG  . CYS A 1 287 ? 216.425 193.134 236.020 1.00 67.43  ? 287 CYS A SG  1 
ATOM   2153  N  N   . ARG A 1 288 ? 221.032 191.892 237.077 1.00 63.04  ? 288 ARG A N   1 
ATOM   2154  C  CA  . ARG A 1 288 ? 222.120 191.190 237.745 1.00 63.62  ? 288 ARG A CA  1 
ATOM   2155  C  C   . ARG A 1 288 ? 222.997 192.150 238.529 1.00 64.70  ? 288 ARG A C   1 
ATOM   2156  O  O   . ARG A 1 288 ? 223.483 191.807 239.610 1.00 72.09  ? 288 ARG A O   1 
ATOM   2157  C  CB  . ARG A 1 288 ? 222.959 190.388 236.749 1.00 70.89  ? 288 ARG A CB  1 
ATOM   2158  C  CG  . ARG A 1 288 ? 222.184 189.336 235.975 1.00 74.96  ? 288 ARG A CG  1 
ATOM   2159  C  CD  . ARG A 1 288 ? 223.107 188.407 235.192 1.00 79.27  ? 288 ARG A CD  1 
ATOM   2160  N  NE  . ARG A 1 288 ? 224.456 188.940 235.034 1.00 83.91  ? 288 ARG A NE  1 
ATOM   2161  C  CZ  . ARG A 1 288 ? 225.123 188.963 233.887 1.00 87.72  ? 288 ARG A CZ  1 
ATOM   2162  N  NH1 . ARG A 1 288 ? 224.598 188.481 232.772 1.00 89.19  ? 288 ARG A NH1 1 
ATOM   2163  N  NH2 . ARG A 1 288 ? 226.351 189.472 233.861 1.00 83.00  ? 288 ARG A NH2 1 
ATOM   2164  N  N   . ASN A 1 289 ? 223.214 193.361 238.015 1.00 62.84  ? 289 ASN A N   1 
ATOM   2165  C  CA  . ASN A 1 289 ? 223.960 194.341 238.796 1.00 66.31  ? 289 ASN A CA  1 
ATOM   2166  C  C   . ASN A 1 289 ? 223.213 194.710 240.072 1.00 70.80  ? 289 ASN A C   1 
ATOM   2167  O  O   . ASN A 1 289 ? 223.817 194.797 241.150 1.00 72.80  ? 289 ASN A O   1 
ATOM   2168  C  CB  . ASN A 1 289 ? 224.240 195.582 237.956 1.00 63.24  ? 289 ASN A CB  1 
ATOM   2169  C  CG  . ASN A 1 289 ? 225.598 195.546 237.315 1.00 60.29  ? 289 ASN A CG  1 
ATOM   2170  O  OD1 . ASN A 1 289 ? 226.608 195.786 237.969 1.00 62.80  ? 289 ASN A OD1 1 
ATOM   2171  N  ND2 . ASN A 1 289 ? 225.635 195.241 236.030 1.00 59.06  ? 289 ASN A ND2 1 
ATOM   2172  N  N   . ILE A 1 290 ? 221.894 194.920 239.977 1.00 70.04  ? 290 ILE A N   1 
ATOM   2173  C  CA  . ILE A 1 290 ? 221.127 195.252 241.177 1.00 68.42  ? 290 ILE A CA  1 
ATOM   2174  C  C   . ILE A 1 290 ? 221.219 194.126 242.197 1.00 76.37  ? 290 ILE A C   1 
ATOM   2175  O  O   . ILE A 1 290 ? 221.442 194.365 243.389 1.00 81.26  ? 290 ILE A O   1 
ATOM   2176  C  CB  . ILE A 1 290 ? 219.662 195.568 240.835 1.00 62.76  ? 290 ILE A CB  1 
ATOM   2177  C  CG1 . ILE A 1 290 ? 219.553 196.801 239.954 1.00 62.51  ? 290 ILE A CG1 1 
ATOM   2178  C  CG2 . ILE A 1 290 ? 218.868 195.788 242.094 1.00 64.28  ? 290 ILE A CG2 1 
ATOM   2179  C  CD1 . ILE A 1 290 ? 218.134 197.135 239.622 1.00 61.43  ? 290 ILE A CD1 1 
ATOM   2180  N  N   . GLU A 1 291 ? 221.060 192.881 241.746 1.00 76.13  ? 291 GLU A N   1 
ATOM   2181  C  CA  . GLU A 1 291 ? 221.204 191.744 242.649 1.00 77.44  ? 291 GLU A CA  1 
ATOM   2182  C  C   . GLU A 1 291 ? 222.611 191.669 243.229 1.00 78.80  ? 291 GLU A C   1 
ATOM   2183  O  O   . GLU A 1 291 ? 222.791 191.242 244.372 1.00 80.93  ? 291 GLU A O   1 
ATOM   2184  C  CB  . GLU A 1 291 ? 220.854 190.449 241.914 1.00 79.45  ? 291 GLU A CB  1 
ATOM   2185  C  CG  . GLU A 1 291 ? 221.400 189.183 242.559 1.00 89.00  ? 291 GLU A CG  1 
ATOM   2186  C  CD  . GLU A 1 291 ? 220.476 187.994 242.398 1.00 101.33 ? 291 GLU A CD  1 
ATOM   2187  O  OE1 . GLU A 1 291 ? 219.929 187.808 241.290 1.00 105.29 ? 291 GLU A OE1 1 
ATOM   2188  O  OE2 . GLU A 1 291 ? 220.294 187.246 243.381 1.00 101.16 ? 291 GLU A OE2 1 
ATOM   2189  N  N   . SER A 1 292 ? 223.620 192.076 242.461 1.00 77.00  ? 292 SER A N   1 
ATOM   2190  C  CA  . SER A 1 292 ? 224.971 192.129 243.003 1.00 73.78  ? 292 SER A CA  1 
ATOM   2191  C  C   . SER A 1 292 ? 225.060 193.136 244.138 1.00 78.36  ? 292 SER A C   1 
ATOM   2192  O  O   . SER A 1 292 ? 225.746 192.898 245.138 1.00 81.24  ? 292 SER A O   1 
ATOM   2193  C  CB  . SER A 1 292 ? 225.966 192.474 241.898 1.00 75.17  ? 292 SER A CB  1 
ATOM   2194  O  OG  . SER A 1 292 ? 225.890 193.847 241.559 1.00 77.37  ? 292 SER A OG  1 
ATOM   2195  N  N   . VAL A 1 293 ? 224.378 194.273 244.000 1.00 81.03  ? 293 VAL A N   1 
ATOM   2196  C  CA  . VAL A 1 293 ? 224.422 195.291 245.048 1.00 82.22  ? 293 VAL A CA  1 
ATOM   2197  C  C   . VAL A 1 293 ? 223.693 194.807 246.296 1.00 82.68  ? 293 VAL A C   1 
ATOM   2198  O  O   . VAL A 1 293 ? 224.193 194.942 247.417 1.00 83.18  ? 293 VAL A O   1 
ATOM   2199  C  CB  . VAL A 1 293 ? 223.840 196.619 244.534 1.00 79.26  ? 293 VAL A CB  1 
ATOM   2200  C  CG1 . VAL A 1 293 ? 223.815 197.647 245.649 1.00 77.78  ? 293 VAL A CG1 1 
ATOM   2201  C  CG2 . VAL A 1 293 ? 224.649 197.130 243.352 1.00 77.55  ? 293 VAL A CG2 1 
ATOM   2202  N  N   . LEU A 1 294 ? 222.504 194.240 246.121 1.00 82.83  ? 294 LEU A N   1 
ATOM   2203  C  CA  . LEU A 1 294 ? 221.678 193.769 247.227 1.00 88.08  ? 294 LEU A CA  1 
ATOM   2204  C  C   . LEU A 1 294 ? 221.827 192.256 247.341 1.00 93.57  ? 294 LEU A C   1 
ATOM   2205  O  O   . LEU A 1 294 ? 221.360 191.521 246.466 1.00 91.57  ? 294 LEU A O   1 
ATOM   2206  C  CB  . LEU A 1 294 ? 220.216 194.151 247.004 1.00 81.75  ? 294 LEU A CB  1 
ATOM   2207  C  CG  . LEU A 1 294 ? 219.971 195.585 246.542 1.00 73.14  ? 294 LEU A CG  1 
ATOM   2208  C  CD1 . LEU A 1 294 ? 218.490 195.840 246.397 1.00 69.75  ? 294 LEU A CD1 1 
ATOM   2209  C  CD2 . LEU A 1 294 ? 220.587 196.557 247.522 1.00 75.68  ? 294 LEU A CD2 1 
ATOM   2210  N  N   . ASN A 1 295 ? 222.404 191.797 248.458 1.00 96.78  ? 295 ASN A N   1 
ATOM   2211  C  CA  . ASN A 1 295 ? 223.029 190.475 248.512 1.00 95.96  ? 295 ASN A CA  1 
ATOM   2212  C  C   . ASN A 1 295 ? 222.106 189.366 248.010 1.00 96.51  ? 295 ASN A C   1 
ATOM   2213  O  O   . ASN A 1 295 ? 222.505 188.549 247.174 1.00 96.33  ? 295 ASN A O   1 
ATOM   2214  C  CB  . ASN A 1 295 ? 223.502 190.183 249.937 1.00 99.65  ? 295 ASN A CB  1 
ATOM   2215  C  CG  . ASN A 1 295 ? 224.726 190.990 250.322 1.00 103.45 ? 295 ASN A CG  1 
ATOM   2216  O  OD1 . ASN A 1 295 ? 225.859 190.545 250.138 1.00 107.59 ? 295 ASN A OD1 1 
ATOM   2217  N  ND2 . ASN A 1 295 ? 224.504 192.181 250.865 1.00 101.35 ? 295 ASN A ND2 1 
ATOM   2218  N  N   . GLU A 1 296 ? 220.872 189.315 248.503 1.00 98.68  ? 296 GLU A N   1 
ATOM   2219  C  CA  . GLU A 1 296 ? 219.887 188.354 248.016 1.00 96.87  ? 296 GLU A CA  1 
ATOM   2220  C  C   . GLU A 1 296 ? 218.681 189.125 247.505 1.00 93.39  ? 296 GLU A C   1 
ATOM   2221  O  O   . GLU A 1 296 ? 218.016 189.821 248.279 1.00 94.51  ? 296 GLU A O   1 
ATOM   2222  C  CB  . GLU A 1 296 ? 219.449 187.352 249.094 1.00 93.76  ? 296 GLU A CB  1 
ATOM   2223  C  CG  . GLU A 1 296 ? 220.530 186.707 249.982 1.00 96.47  ? 296 GLU A CG  1 
ATOM   2224  C  CD  . GLU A 1 296 ? 221.367 187.691 250.776 1.00 106.43 ? 296 GLU A CD  1 
ATOM   2225  O  OE1 . GLU A 1 296 ? 220.917 188.842 250.958 1.00 109.19 ? 296 GLU A OE1 1 
ATOM   2226  O  OE2 . GLU A 1 296 ? 222.472 187.314 251.219 1.00 109.05 ? 296 GLU A OE2 1 
ATOM   2227  N  N   . SER A 1 297 ? 218.392 188.997 246.213 1.00 90.41  ? 297 SER A N   1 
ATOM   2228  C  CA  . SER A 1 297 ? 217.295 189.755 245.631 1.00 90.65  ? 297 SER A CA  1 
ATOM   2229  C  C   . SER A 1 297 ? 216.854 189.117 244.324 1.00 90.89  ? 297 SER A C   1 
ATOM   2230  O  O   . SER A 1 297 ? 217.607 188.385 243.679 1.00 95.06  ? 297 SER A O   1 
ATOM   2231  C  CB  . SER A 1 297 ? 217.695 191.212 245.388 1.00 89.46  ? 297 SER A CB  1 
ATOM   2232  O  OG  . SER A 1 297 ? 218.312 191.353 244.121 1.00 85.51  ? 297 SER A OG  1 
ATOM   2233  N  N   . HIS A 1 298 ? 215.616 189.421 243.944 1.00 86.80  ? 298 HIS A N   1 
ATOM   2234  C  CA  . HIS A 1 298 ? 215.071 189.084 242.637 1.00 87.70  ? 298 HIS A CA  1 
ATOM   2235  C  C   . HIS A 1 298 ? 214.518 190.352 242.006 1.00 85.44  ? 298 HIS A C   1 
ATOM   2236  O  O   . HIS A 1 298 ? 213.717 191.058 242.625 1.00 85.40  ? 298 HIS A O   1 
ATOM   2237  C  CB  . HIS A 1 298 ? 213.980 188.018 242.737 1.00 89.52  ? 298 HIS A CB  1 
ATOM   2238  C  CG  . HIS A 1 298 ? 213.652 187.367 241.430 1.00 96.05  ? 298 HIS A CG  1 
ATOM   2239  N  ND1 . HIS A 1 298 ? 212.493 187.634 240.735 1.00 93.32  ? 298 HIS A ND1 1 
ATOM   2240  C  CD2 . HIS A 1 298 ? 214.336 186.465 240.687 1.00 101.61 ? 298 HIS A CD2 1 
ATOM   2241  C  CE1 . HIS A 1 298 ? 212.474 186.922 239.622 1.00 94.28  ? 298 HIS A CE1 1 
ATOM   2242  N  NE2 . HIS A 1 298 ? 213.581 186.204 239.569 1.00 97.97  ? 298 HIS A NE2 1 
ATOM   2243  N  N   . VAL A 1 299 ? 214.950 190.643 240.785 1.00 81.88  ? 299 VAL A N   1 
ATOM   2244  C  CA  . VAL A 1 299 ? 214.611 191.884 240.104 1.00 74.00  ? 299 VAL A CA  1 
ATOM   2245  C  C   . VAL A 1 299 ? 213.949 191.544 238.782 1.00 70.46  ? 299 VAL A C   1 
ATOM   2246  O  O   . VAL A 1 299 ? 214.470 190.728 238.017 1.00 76.52  ? 299 VAL A O   1 
ATOM   2247  C  CB  . VAL A 1 299 ? 215.854 192.761 239.867 1.00 78.42  ? 299 VAL A CB  1 
ATOM   2248  C  CG1 . VAL A 1 299 ? 215.446 194.120 239.322 1.00 76.43  ? 299 VAL A CG1 1 
ATOM   2249  C  CG2 . VAL A 1 299 ? 216.657 192.906 241.151 1.00 78.74  ? 299 VAL A CG2 1 
ATOM   2250  N  N   . SER A 1 300 ? 212.816 192.174 238.507 1.00 66.64  ? 300 SER A N   1 
ATOM   2251  C  CA  . SER A 1 300 ? 212.096 191.948 237.267 1.00 68.05  ? 300 SER A CA  1 
ATOM   2252  C  C   . SER A 1 300 ? 211.787 193.281 236.604 1.00 61.48  ? 300 SER A C   1 
ATOM   2253  O  O   . SER A 1 300 ? 211.575 194.299 237.275 1.00 66.01  ? 300 SER A O   1 
ATOM   2254  C  CB  . SER A 1 300 ? 210.808 191.156 237.505 1.00 76.44  ? 300 SER A CB  1 
ATOM   2255  O  OG  . SER A 1 300 ? 211.095 189.826 237.901 1.00 80.72  ? 300 SER A OG  1 
ATOM   2256  N  N   . LEU A 1 301 ? 211.771 193.259 235.276 1.00 57.05  ? 301 LEU A N   1 
ATOM   2257  C  CA  . LEU A 1 301 ? 211.655 194.461 234.466 1.00 58.84  ? 301 LEU A CA  1 
ATOM   2258  C  C   . LEU A 1 301 ? 210.542 194.286 233.448 1.00 64.84  ? 301 LEU A C   1 
ATOM   2259  O  O   . LEU A 1 301 ? 210.463 193.251 232.783 1.00 73.37  ? 301 LEU A O   1 
ATOM   2260  C  CB  . LEU A 1 301 ? 212.973 194.769 233.758 1.00 57.08  ? 301 LEU A CB  1 
ATOM   2261  C  CG  . LEU A 1 301 ? 214.041 195.457 234.601 1.00 55.67  ? 301 LEU A CG  1 
ATOM   2262  C  CD1 . LEU A 1 301 ? 215.295 195.749 233.807 1.00 54.13  ? 301 LEU A CD1 1 
ATOM   2263  C  CD2 . LEU A 1 301 ? 213.463 196.730 235.151 1.00 60.89  ? 301 LEU A CD2 1 
ATOM   2264  N  N   . PHE A 1 302 ? 209.692 195.294 233.316 1.00 65.52  ? 302 PHE A N   1 
ATOM   2265  C  CA  . PHE A 1 302 ? 208.589 195.261 232.372 1.00 73.79  ? 302 PHE A CA  1 
ATOM   2266  C  C   . PHE A 1 302 ? 208.678 196.493 231.490 1.00 79.72  ? 302 PHE A C   1 
ATOM   2267  O  O   . PHE A 1 302 ? 208.698 197.619 231.999 1.00 82.17  ? 302 PHE A O   1 
ATOM   2268  C  CB  . PHE A 1 302 ? 207.239 195.223 233.095 1.00 78.42  ? 302 PHE A CB  1 
ATOM   2269  C  CG  . PHE A 1 302 ? 206.958 193.927 233.802 1.00 78.56  ? 302 PHE A CG  1 
ATOM   2270  C  CD1 . PHE A 1 302 ? 207.459 192.734 233.318 1.00 78.02  ? 302 PHE A CD1 1 
ATOM   2271  C  CD2 . PHE A 1 302 ? 206.178 193.905 234.943 1.00 76.96  ? 302 PHE A CD2 1 
ATOM   2272  C  CE1 . PHE A 1 302 ? 207.199 191.547 233.964 1.00 74.63  ? 302 PHE A CE1 1 
ATOM   2273  C  CE2 . PHE A 1 302 ? 205.913 192.721 235.590 1.00 78.02  ? 302 PHE A CE2 1 
ATOM   2274  C  CZ  . PHE A 1 302 ? 206.426 191.539 235.101 1.00 77.10  ? 302 PHE A CZ  1 
ATOM   2275  N  N   . ALA A 1 303 ? 208.703 196.281 230.178 1.00 83.47  ? 303 ALA A N   1 
ATOM   2276  C  CA  . ALA A 1 303 ? 208.691 197.366 229.208 1.00 84.90  ? 303 ALA A CA  1 
ATOM   2277  C  C   . ALA A 1 303 ? 207.288 197.490 228.633 1.00 88.53  ? 303 ALA A C   1 
ATOM   2278  O  O   . ALA A 1 303 ? 206.699 196.493 228.213 1.00 90.68  ? 303 ALA A O   1 
ATOM   2279  C  CB  . ALA A 1 303 ? 209.707 197.118 228.096 1.00 79.50  ? 303 ALA A CB  1 
ATOM   2280  N  N   . LEU A 1 304 ? 206.749 198.702 228.629 1.00 85.77  ? 304 LEU A N   1 
ATOM   2281  C  CA  . LEU A 1 304 ? 205.363 198.905 228.242 1.00 91.89  ? 304 LEU A CA  1 
ATOM   2282  C  C   . LEU A 1 304 ? 205.241 199.009 226.728 1.00 96.42  ? 304 LEU A C   1 
ATOM   2283  O  O   . LEU A 1 304 ? 205.946 199.798 226.091 1.00 95.63  ? 304 LEU A O   1 
ATOM   2284  C  CB  . LEU A 1 304 ? 204.806 200.166 228.900 1.00 90.82  ? 304 LEU A CB  1 
ATOM   2285  C  CG  . LEU A 1 304 ? 204.642 200.153 230.421 1.00 90.95  ? 304 LEU A CG  1 
ATOM   2286  C  CD1 . LEU A 1 304 ? 204.241 201.531 230.925 1.00 83.42  ? 304 LEU A CD1 1 
ATOM   2287  C  CD2 . LEU A 1 304 ? 203.623 199.108 230.846 1.00 93.13  ? 304 LEU A CD2 1 
ATOM   2288  N  N   . ARG A 1 305 ? 204.347 198.206 226.157 1.00 99.44  ? 305 ARG A N   1 
ATOM   2289  C  CA  . ARG A 1 305 ? 203.987 198.294 224.750 1.00 100.02 ? 305 ARG A CA  1 
ATOM   2290  C  C   . ARG A 1 305 ? 202.477 198.440 224.663 1.00 98.78  ? 305 ARG A C   1 
ATOM   2291  O  O   . ARG A 1 305 ? 201.741 197.632 225.237 1.00 97.26  ? 305 ARG A O   1 
ATOM   2292  C  CB  . ARG A 1 305 ? 204.458 197.061 223.976 1.00 99.45  ? 305 ARG A CB  1 
ATOM   2293  C  CG  . ARG A 1 305 ? 205.956 197.020 223.752 1.00 105.08 ? 305 ARG A CG  1 
ATOM   2294  C  CD  . ARG A 1 305 ? 206.315 196.176 222.542 1.00 110.36 ? 305 ARG A CD  1 
ATOM   2295  N  NE  . ARG A 1 305 ? 207.748 196.199 222.273 1.00 116.79 ? 305 ARG A NE  1 
ATOM   2296  C  CZ  . ARG A 1 305 ? 208.370 195.364 221.452 1.00 117.27 ? 305 ARG A CZ  1 
ATOM   2297  N  NH1 . ARG A 1 305 ? 207.713 194.419 220.799 1.00 116.15 ? 305 ARG A NH1 1 
ATOM   2298  N  NH2 . ARG A 1 305 ? 209.684 195.478 221.283 1.00 112.11 ? 305 ARG A NH2 1 
ATOM   2299  N  N   . ASN A 1 306 ? 202.023 199.482 223.969 1.00 100.41 ? 306 ASN A N   1 
ATOM   2300  C  CA  . ASN A 1 306 ? 200.600 199.741 223.753 1.00 102.84 ? 306 ASN A CA  1 
ATOM   2301  C  C   . ASN A 1 306 ? 199.820 199.816 225.062 1.00 102.05 ? 306 ASN A C   1 
ATOM   2302  O  O   . ASN A 1 306 ? 198.612 199.562 225.088 1.00 102.39 ? 306 ASN A O   1 
ATOM   2303  C  CB  . ASN A 1 306 ? 199.982 198.690 222.825 1.00 107.83 ? 306 ASN A CB  1 
ATOM   2304  C  CG  . ASN A 1 306 ? 200.829 198.430 221.594 1.00 110.38 ? 306 ASN A CG  1 
ATOM   2305  O  OD1 . ASN A 1 306 ? 201.538 199.316 221.117 1.00 112.33 ? 306 ASN A OD1 1 
ATOM   2306  N  ND2 . ASN A 1 306 ? 200.757 197.211 221.073 1.00 107.01 ? 306 ASN A ND2 1 
ATOM   2307  N  N   . GLY A 1 307 ? 200.492 200.162 226.159 1.00 101.07 ? 307 GLY A N   1 
ATOM   2308  C  CA  . GLY A 1 307 ? 199.863 200.309 227.453 1.00 101.08 ? 307 GLY A CA  1 
ATOM   2309  C  C   . GLY A 1 307 ? 199.960 199.090 228.345 1.00 97.50  ? 307 GLY A C   1 
ATOM   2310  O  O   . GLY A 1 307 ? 199.464 199.130 229.478 1.00 92.92  ? 307 GLY A O   1 
ATOM   2311  N  N   . MET A 1 308 ? 200.579 198.011 227.881 1.00 98.28  ? 308 MET A N   1 
ATOM   2312  C  CA  . MET A 1 308 ? 200.639 196.855 228.755 1.00 95.17  ? 308 MET A CA  1 
ATOM   2313  C  C   . MET A 1 308 ? 202.071 196.346 228.889 1.00 91.18  ? 308 MET A C   1 
ATOM   2314  O  O   . MET A 1 308 ? 202.882 196.506 227.974 1.00 92.99  ? 308 MET A O   1 
ATOM   2315  C  CB  . MET A 1 308 ? 199.672 195.760 228.261 1.00 103.27 ? 308 MET A CB  1 
ATOM   2316  C  CG  . MET A 1 308 ? 199.876 195.107 226.873 1.00 108.98 ? 308 MET A CG  1 
ATOM   2317  S  SD  . MET A 1 308 ? 201.479 194.527 226.295 1.00 118.45 ? 308 MET A SD  1 
ATOM   2318  C  CE  . MET A 1 308 ? 201.810 193.270 227.526 1.00 99.44  ? 308 MET A CE  1 
ATOM   2319  N  N   . PRO A 1 309 ? 202.423 195.785 230.040 1.00 87.01  ? 309 PRO A N   1 
ATOM   2320  C  CA  . PRO A 1 309 ? 203.829 195.460 230.301 1.00 85.02  ? 309 PRO A CA  1 
ATOM   2321  C  C   . PRO A 1 309 ? 204.266 194.107 229.770 1.00 83.82  ? 309 PRO A C   1 
ATOM   2322  O  O   . PRO A 1 309 ? 203.717 193.070 230.149 1.00 83.43  ? 309 PRO A O   1 
ATOM   2323  C  CB  . PRO A 1 309 ? 203.905 195.503 231.829 1.00 79.65  ? 309 PRO A CB  1 
ATOM   2324  C  CG  . PRO A 1 309 ? 202.549 195.100 232.266 1.00 82.31  ? 309 PRO A CG  1 
ATOM   2325  C  CD  . PRO A 1 309 ? 201.589 195.631 231.241 1.00 86.42  ? 309 PRO A CD  1 
ATOM   2326  N  N   . ILE A 1 310 ? 205.273 194.110 228.907 1.00 81.82  ? 310 ILE A N   1 
ATOM   2327  C  CA  . ILE A 1 310 ? 205.900 192.900 228.398 1.00 80.05  ? 310 ILE A CA  1 
ATOM   2328  C  C   . ILE A 1 310 ? 207.140 192.627 229.229 1.00 77.34  ? 310 ILE A C   1 
ATOM   2329  O  O   . ILE A 1 310 ? 207.927 193.541 229.510 1.00 79.80  ? 310 ILE A O   1 
ATOM   2330  C  CB  . ILE A 1 310 ? 206.258 193.040 226.907 1.00 82.14  ? 310 ILE A CB  1 
ATOM   2331  C  CG1 . ILE A 1 310 ? 204.995 193.084 226.049 1.00 86.84  ? 310 ILE A CG1 1 
ATOM   2332  C  CG2 . ILE A 1 310 ? 207.164 191.903 226.461 1.00 82.95  ? 310 ILE A CG2 1 
ATOM   2333  C  CD1 . ILE A 1 310 ? 205.261 193.332 224.580 1.00 96.17  ? 310 ILE A CD1 1 
ATOM   2334  N  N   . HIS A 1 311 ? 207.306 191.375 229.641 1.00 69.80  ? 311 HIS A N   1 
ATOM   2335  C  CA  . HIS A 1 311 ? 208.472 190.997 230.420 1.00 71.00  ? 311 HIS A CA  1 
ATOM   2336  C  C   . HIS A 1 311 ? 209.744 191.231 229.616 1.00 75.03  ? 311 HIS A C   1 
ATOM   2337  O  O   . HIS A 1 311 ? 209.829 190.856 228.443 1.00 76.79  ? 311 HIS A O   1 
ATOM   2338  C  CB  . HIS A 1 311 ? 208.368 189.535 230.836 1.00 66.24  ? 311 HIS A CB  1 
ATOM   2339  C  CG  . HIS A 1 311 ? 209.691 188.887 231.078 1.00 72.68  ? 311 HIS A CG  1 
ATOM   2340  N  ND1 . HIS A 1 311 ? 210.435 189.122 232.212 1.00 74.82  ? 311 HIS A ND1 1 
ATOM   2341  C  CD2 . HIS A 1 311 ? 210.406 188.015 230.331 1.00 74.32  ? 311 HIS A CD2 1 
ATOM   2342  C  CE1 . HIS A 1 311 ? 211.552 188.419 232.155 1.00 78.20  ? 311 HIS A CE1 1 
ATOM   2343  N  NE2 . HIS A 1 311 ? 211.559 187.739 231.024 1.00 82.13  ? 311 HIS A NE2 1 
ATOM   2344  N  N   . TRP A 1 312 ? 210.737 191.857 230.251 1.00 72.97  ? 312 TRP A N   1 
ATOM   2345  C  CA  . TRP A 1 312 ? 211.983 192.226 229.596 1.00 66.29  ? 312 TRP A CA  1 
ATOM   2346  C  C   . TRP A 1 312 ? 213.122 191.331 230.063 1.00 64.91  ? 312 TRP A C   1 
ATOM   2347  O  O   . TRP A 1 312 ? 213.791 190.697 229.244 1.00 70.75  ? 312 TRP A O   1 
ATOM   2348  C  CB  . TRP A 1 312 ? 212.274 193.708 229.887 1.00 70.85  ? 312 TRP A CB  1 
ATOM   2349  C  CG  . TRP A 1 312 ? 213.630 194.270 229.481 1.00 72.09  ? 312 TRP A CG  1 
ATOM   2350  C  CD1 . TRP A 1 312 ? 214.709 193.592 228.985 1.00 71.05  ? 312 TRP A CD1 1 
ATOM   2351  C  CD2 . TRP A 1 312 ? 214.040 195.639 229.584 1.00 64.01  ? 312 TRP A CD2 1 
ATOM   2352  N  NE1 . TRP A 1 312 ? 215.747 194.454 228.757 1.00 65.61  ? 312 TRP A NE1 1 
ATOM   2353  C  CE2 . TRP A 1 312 ? 215.362 195.716 229.120 1.00 61.85  ? 312 TRP A CE2 1 
ATOM   2354  C  CE3 . TRP A 1 312 ? 213.410 196.807 230.021 1.00 60.75  ? 312 TRP A CE3 1 
ATOM   2355  C  CZ2 . TRP A 1 312 ? 216.064 196.908 229.081 1.00 63.73  ? 312 TRP A CZ2 1 
ATOM   2356  C  CZ3 . TRP A 1 312 ? 214.105 197.981 229.980 1.00 60.46  ? 312 TRP A CZ3 1 
ATOM   2357  C  CH2 . TRP A 1 312 ? 215.419 198.028 229.513 1.00 62.58  ? 312 TRP A CH2 1 
ATOM   2358  N  N   . ALA A 1 313 ? 213.349 191.260 231.369 1.00 63.54  ? 313 ALA A N   1 
ATOM   2359  C  CA  . ALA A 1 313 ? 214.419 190.435 231.904 1.00 66.77  ? 313 ALA A CA  1 
ATOM   2360  C  C   . ALA A 1 313 ? 214.231 190.286 233.402 1.00 72.72  ? 313 ALA A C   1 
ATOM   2361  O  O   . ALA A 1 313 ? 213.742 191.198 234.073 1.00 75.39  ? 313 ALA A O   1 
ATOM   2362  C  CB  . ALA A 1 313 ? 215.799 191.031 231.611 1.00 64.63  ? 313 ALA A CB  1 
ATOM   2363  N  N   . SER A 1 314 ? 214.623 189.126 233.916 1.00 72.83  ? 314 SER A N   1 
ATOM   2364  C  CA  . SER A 1 314 ? 214.689 188.899 235.349 1.00 75.00  ? 314 SER A CA  1 
ATOM   2365  C  C   . SER A 1 314 ? 215.864 187.980 235.637 1.00 81.69  ? 314 SER A C   1 
ATOM   2366  O  O   . SER A 1 314 ? 216.227 187.141 234.809 1.00 88.16  ? 314 SER A O   1 
ATOM   2367  C  CB  . SER A 1 314 ? 213.394 188.293 235.883 1.00 74.53  ? 314 SER A CB  1 
ATOM   2368  O  OG  . SER A 1 314 ? 212.290 189.092 235.508 1.00 74.45  ? 314 SER A OG  1 
ATOM   2369  N  N   . SER A 1 315 ? 216.459 188.147 236.813 1.00 79.48  ? 315 SER A N   1 
ATOM   2370  C  CA  . SER A 1 315 ? 217.638 187.372 237.160 1.00 87.85  ? 315 SER A CA  1 
ATOM   2371  C  C   . SER A 1 315 ? 217.285 185.897 237.323 1.00 103.88 ? 315 SER A C   1 
ATOM   2372  O  O   . SER A 1 315 ? 216.173 185.539 237.720 1.00 107.39 ? 315 SER A O   1 
ATOM   2373  C  CB  . SER A 1 315 ? 218.268 187.902 238.443 1.00 87.41  ? 315 SER A CB  1 
ATOM   2374  O  OG  . SER A 1 315 ? 217.371 187.771 239.529 1.00 93.83  ? 315 SER A OG  1 
ATOM   2375  N  N   . SER A 1 316 ? 218.256 185.036 237.006 1.00 110.57 ? 316 SER A N   1 
ATOM   2376  C  CA  . SER A 1 316 ? 218.032 183.595 237.039 1.00 114.46 ? 316 SER A CA  1 
ATOM   2377  C  C   . SER A 1 316 ? 217.812 183.062 238.449 1.00 119.39 ? 316 SER A C   1 
ATOM   2378  O  O   . SER A 1 316 ? 217.267 181.963 238.602 1.00 120.56 ? 316 SER A O   1 
ATOM   2379  C  CB  . SER A 1 316 ? 219.211 182.867 236.390 1.00 112.07 ? 316 SER A CB  1 
ATOM   2380  O  OG  . SER A 1 316 ? 220.427 183.176 237.049 1.00 116.08 ? 316 SER A OG  1 
ATOM   2381  N  N   . HIS A 1 317 ? 218.219 183.805 239.479 1.00 118.69 ? 317 HIS A N   1 
ATOM   2382  C  CA  . HIS A 1 317 ? 218.061 183.362 240.865 1.00 119.12 ? 317 HIS A CA  1 
ATOM   2383  C  C   . HIS A 1 317 ? 216.596 183.517 241.262 1.00 117.71 ? 317 HIS A C   1 
ATOM   2384  O  O   . HIS A 1 317 ? 216.195 184.449 241.964 1.00 114.21 ? 317 HIS A O   1 
ATOM   2385  C  CB  . HIS A 1 317 ? 218.983 184.146 241.790 1.00 117.40 ? 317 HIS A CB  1 
ATOM   2386  C  CG  . HIS A 1 317 ? 220.423 183.749 241.689 1.00 122.48 ? 317 HIS A CG  1 
ATOM   2387  N  ND1 . HIS A 1 317 ? 221.128 183.798 240.506 1.00 120.62 ? 317 HIS A ND1 1 
ATOM   2388  C  CD2 . HIS A 1 317 ? 221.290 183.295 242.625 1.00 124.15 ? 317 HIS A CD2 1 
ATOM   2389  C  CE1 . HIS A 1 317 ? 222.367 183.392 240.717 1.00 123.40 ? 317 HIS A CE1 1 
ATOM   2390  N  NE2 . HIS A 1 317 ? 222.492 183.081 241.995 1.00 125.49 ? 317 HIS A NE2 1 
ATOM   2391  N  N   . GLY A 1 318 ? 215.783 182.570 240.804 1.00 118.83 ? 318 GLY A N   1 
ATOM   2392  C  CA  . GLY A 1 318 ? 214.354 182.575 241.025 1.00 117.28 ? 318 GLY A CA  1 
ATOM   2393  C  C   . GLY A 1 318 ? 213.887 181.896 242.293 1.00 118.50 ? 318 GLY A C   1 
ATOM   2394  O  O   . GLY A 1 318 ? 212.687 181.634 242.430 1.00 114.66 ? 318 GLY A O   1 
ATOM   2395  N  N   . ALA A 1 319 ? 214.791 181.595 243.221 1.00 121.09 ? 319 ALA A N   1 
ATOM   2396  C  CA  . ALA A 1 319 ? 214.404 180.953 244.468 1.00 121.55 ? 319 ALA A CA  1 
ATOM   2397  C  C   . ALA A 1 319 ? 213.518 181.873 245.300 1.00 125.70 ? 319 ALA A C   1 
ATOM   2398  O  O   . ALA A 1 319 ? 213.668 183.098 245.288 1.00 125.57 ? 319 ALA A O   1 
ATOM   2399  C  CB  . ALA A 1 319 ? 215.643 180.553 245.270 1.00 119.32 ? 319 ALA A CB  1 
ATOM   2400  N  N   . GLU A 1 320 ? 212.583 181.266 246.025 1.00 126.98 ? 320 GLU A N   1 
ATOM   2401  C  CA  . GLU A 1 320 ? 211.650 182.028 246.842 1.00 124.38 ? 320 GLU A CA  1 
ATOM   2402  C  C   . GLU A 1 320 ? 212.370 182.711 247.999 1.00 121.61 ? 320 GLU A C   1 
ATOM   2403  O  O   . GLU A 1 320 ? 213.351 182.197 248.543 1.00 119.97 ? 320 GLU A O   1 
ATOM   2404  C  CB  . GLU A 1 320 ? 210.544 181.120 247.378 1.00 125.03 ? 320 GLU A CB  1 
ATOM   2405  C  CG  . GLU A 1 320 ? 209.739 180.418 246.296 1.00 127.66 ? 320 GLU A CG  1 
ATOM   2406  C  CD  . GLU A 1 320 ? 208.574 179.626 246.858 1.00 129.49 ? 320 GLU A CD  1 
ATOM   2407  O  OE1 . GLU A 1 320 ? 208.634 179.238 248.043 1.00 132.60 ? 320 GLU A OE1 1 
ATOM   2408  O  OE2 . GLU A 1 320 ? 207.598 179.393 246.114 1.00 129.78 ? 320 GLU A OE2 1 
ATOM   2409  N  N   . ILE A 1 321 ? 211.869 183.886 248.371 1.00 123.97 ? 321 ILE A N   1 
ATOM   2410  C  CA  . ILE A 1 321 ? 212.431 184.688 249.451 1.00 126.35 ? 321 ILE A CA  1 
ATOM   2411  C  C   . ILE A 1 321 ? 211.383 184.810 250.546 1.00 127.94 ? 321 ILE A C   1 
ATOM   2412  O  O   . ILE A 1 321 ? 210.223 185.136 250.268 1.00 127.81 ? 321 ILE A O   1 
ATOM   2413  C  CB  . ILE A 1 321 ? 212.872 186.078 248.957 1.00 123.52 ? 321 ILE A CB  1 
ATOM   2414  C  CG1 . ILE A 1 321 ? 213.675 185.954 247.660 1.00 121.51 ? 321 ILE A CG1 1 
ATOM   2415  C  CG2 . ILE A 1 321 ? 213.691 186.784 250.024 1.00 116.90 ? 321 ILE A CG2 1 
ATOM   2416  C  CD1 . ILE A 1 321 ? 214.055 187.284 247.047 1.00 108.31 ? 321 ILE A CD1 1 
ATOM   2417  N  N   . GLN A 1 322 ? 211.791 184.549 251.785 1.00 130.05 ? 322 GLN A N   1 
ATOM   2418  C  CA  . GLN A 1 322 ? 210.867 184.538 252.914 1.00 132.32 ? 322 GLN A CA  1 
ATOM   2419  C  C   . GLN A 1 322 ? 210.541 185.971 253.319 1.00 131.54 ? 322 GLN A C   1 
ATOM   2420  O  O   . GLN A 1 322 ? 211.415 186.703 253.794 1.00 129.25 ? 322 GLN A O   1 
ATOM   2421  C  CB  . GLN A 1 322 ? 211.467 183.761 254.081 1.00 132.73 ? 322 GLN A CB  1 
ATOM   2422  C  CG  . GLN A 1 322 ? 211.750 182.299 253.770 1.00 133.52 ? 322 GLN A CG  1 
ATOM   2423  C  CD  . GLN A 1 322 ? 212.044 181.483 255.013 1.00 139.72 ? 322 GLN A CD  1 
ATOM   2424  O  OE1 . GLN A 1 322 ? 212.084 182.014 256.123 1.00 143.94 ? 322 GLN A OE1 1 
ATOM   2425  N  NE2 . GLN A 1 322 ? 212.250 180.184 254.833 1.00 137.49 ? 322 GLN A NE2 1 
ATOM   2426  N  N   . ASN A 1 323 ? 209.278 186.365 253.140 1.00 130.67 ? 323 ASN A N   1 
ATOM   2427  C  CA  . ASN A 1 323 ? 208.787 187.684 253.542 1.00 128.40 ? 323 ASN A CA  1 
ATOM   2428  C  C   . ASN A 1 323 ? 209.606 188.804 252.901 1.00 125.93 ? 323 ASN A C   1 
ATOM   2429  O  O   . ASN A 1 323 ? 210.059 189.736 253.567 1.00 119.79 ? 323 ASN A O   1 
ATOM   2430  C  CB  . ASN A 1 323 ? 208.769 187.822 255.066 1.00 129.36 ? 323 ASN A CB  1 
ATOM   2431  C  CG  . ASN A 1 323 ? 208.003 186.704 255.743 1.00 131.34 ? 323 ASN A CG  1 
ATOM   2432  O  OD1 . ASN A 1 323 ? 207.050 186.161 255.184 1.00 133.21 ? 323 ASN A OD1 1 
ATOM   2433  N  ND2 . ASN A 1 323 ? 208.418 186.352 256.955 1.00 129.99 ? 323 ASN A ND2 1 
ATOM   2434  N  N   . ALA A 1 324 ? 209.794 188.703 251.588 1.00 125.22 ? 324 ALA A N   1 
ATOM   2435  C  CA  . ALA A 1 324 ? 210.543 189.714 250.860 1.00 118.77 ? 324 ALA A CA  1 
ATOM   2436  C  C   . ALA A 1 324 ? 209.752 191.018 250.781 1.00 115.91 ? 324 ALA A C   1 
ATOM   2437  O  O   . ALA A 1 324 ? 208.527 191.045 250.925 1.00 117.40 ? 324 ALA A O   1 
ATOM   2438  C  CB  . ALA A 1 324 ? 210.884 189.222 249.454 1.00 110.87 ? 324 ALA A CB  1 
ATOM   2439  N  N   . GLN A 1 325 ? 210.476 192.112 250.557 1.00 107.53 ? 325 GLN A N   1 
ATOM   2440  C  CA  . GLN A 1 325 ? 209.886 193.436 250.420 1.00 98.62  ? 325 GLN A CA  1 
ATOM   2441  C  C   . GLN A 1 325 ? 210.053 193.923 248.989 1.00 90.88  ? 325 GLN A C   1 
ATOM   2442  O  O   . GLN A 1 325 ? 211.174 193.984 248.477 1.00 90.28  ? 325 GLN A O   1 
ATOM   2443  C  CB  . GLN A 1 325 ? 210.528 194.423 251.396 1.00 96.96  ? 325 GLN A CB  1 
ATOM   2444  C  CG  . GLN A 1 325 ? 210.217 194.132 252.854 1.00 100.49 ? 325 GLN A CG  1 
ATOM   2445  C  CD  . GLN A 1 325 ? 210.769 195.186 253.789 1.00 99.78  ? 325 GLN A CD  1 
ATOM   2446  O  OE1 . GLN A 1 325 ? 211.032 194.915 254.961 1.00 99.76  ? 325 GLN A OE1 1 
ATOM   2447  N  NE2 . GLN A 1 325 ? 210.947 196.397 253.276 1.00 96.39  ? 325 GLN A NE2 1 
ATOM   2448  N  N   . SER A 1 326 ? 208.942 194.269 248.354 1.00 86.99  ? 326 SER A N   1 
ATOM   2449  C  CA  . SER A 1 326 ? 208.941 194.721 246.974 1.00 81.51  ? 326 SER A CA  1 
ATOM   2450  C  C   . SER A 1 326 ? 209.104 196.236 246.902 1.00 80.05  ? 326 SER A C   1 
ATOM   2451  O  O   . SER A 1 326 ? 209.148 196.934 247.915 1.00 81.82  ? 326 SER A O   1 
ATOM   2452  C  CB  . SER A 1 326 ? 207.654 194.293 246.275 1.00 80.07  ? 326 SER A CB  1 
ATOM   2453  O  OG  . SER A 1 326 ? 207.584 192.884 246.163 1.00 84.88  ? 326 SER A OG  1 
ATOM   2454  N  N   . TRP A 1 327 ? 209.190 196.740 245.675 1.00 76.84  ? 327 TRP A N   1 
ATOM   2455  C  CA  . TRP A 1 327 ? 209.469 198.151 245.424 1.00 67.33  ? 327 TRP A CA  1 
ATOM   2456  C  C   . TRP A 1 327 ? 209.121 198.438 243.975 1.00 65.70  ? 327 TRP A C   1 
ATOM   2457  O  O   . TRP A 1 327 ? 209.695 197.822 243.074 1.00 64.65  ? 327 TRP A O   1 
ATOM   2458  C  CB  . TRP A 1 327 ? 210.934 198.454 245.708 1.00 65.30  ? 327 TRP A CB  1 
ATOM   2459  C  CG  . TRP A 1 327 ? 211.224 199.780 246.349 1.00 70.77  ? 327 TRP A CG  1 
ATOM   2460  C  CD1 . TRP A 1 327 ? 212.162 200.680 245.948 1.00 72.13  ? 327 TRP A CD1 1 
ATOM   2461  C  CD2 . TRP A 1 327 ? 210.598 200.347 247.509 1.00 73.92  ? 327 TRP A CD2 1 
ATOM   2462  N  NE1 . TRP A 1 327 ? 212.158 201.775 246.775 1.00 72.04  ? 327 TRP A NE1 1 
ATOM   2463  C  CE2 . TRP A 1 327 ? 211.206 201.595 247.742 1.00 70.72  ? 327 TRP A CE2 1 
ATOM   2464  C  CE3 . TRP A 1 327 ? 209.582 199.924 248.370 1.00 74.87  ? 327 TRP A CE3 1 
ATOM   2465  C  CZ2 . TRP A 1 327 ? 210.834 202.423 248.793 1.00 66.61  ? 327 TRP A CZ2 1 
ATOM   2466  C  CZ3 . TRP A 1 327 ? 209.213 200.749 249.415 1.00 75.65  ? 327 TRP A CZ3 1 
ATOM   2467  C  CH2 . TRP A 1 327 ? 209.837 201.984 249.617 1.00 70.59  ? 327 TRP A CH2 1 
ATOM   2468  N  N   . SER A 1 328 ? 208.190 199.354 243.741 1.00 64.19  ? 328 SER A N   1 
ATOM   2469  C  CA  . SER A 1 328 ? 207.709 199.640 242.399 1.00 62.32  ? 328 SER A CA  1 
ATOM   2470  C  C   . SER A 1 328 ? 208.113 201.047 241.997 1.00 60.00  ? 328 SER A C   1 
ATOM   2471  O  O   . SER A 1 328 ? 207.807 202.009 242.704 1.00 60.33  ? 328 SER A O   1 
ATOM   2472  C  CB  . SER A 1 328 ? 206.191 199.489 242.316 1.00 64.89  ? 328 SER A CB  1 
ATOM   2473  O  OG  . SER A 1 328 ? 205.537 200.597 242.908 1.00 67.67  ? 328 SER A OG  1 
ATOM   2474  N  N   . ALA A 1 329 ? 208.785 201.162 240.858 1.00 56.09  ? 329 ALA A N   1 
ATOM   2475  C  CA  . ALA A 1 329 ? 209.175 202.444 240.299 1.00 53.45  ? 329 ALA A CA  1 
ATOM   2476  C  C   . ALA A 1 329 ? 208.675 202.537 238.869 1.00 61.20  ? 329 ALA A C   1 
ATOM   2477  O  O   . ALA A 1 329 ? 208.765 201.571 238.109 1.00 65.04  ? 329 ALA A O   1 
ATOM   2478  C  CB  . ALA A 1 329 ? 210.691 202.629 240.330 1.00 52.29  ? 329 ALA A CB  1 
ATOM   2479  N  N   . THR A 1 330 ? 208.151 203.701 238.505 1.00 67.67  ? 330 THR A N   1 
ATOM   2480  C  CA  . THR A 1 330 ? 207.590 203.928 237.176 1.00 74.18  ? 330 THR A CA  1 
ATOM   2481  C  C   . THR A 1 330 ? 208.646 204.600 236.306 1.00 73.68  ? 330 THR A C   1 
ATOM   2482  O  O   . THR A 1 330 ? 208.886 205.802 236.418 1.00 76.55  ? 330 THR A O   1 
ATOM   2483  C  CB  . THR A 1 330 ? 206.327 204.776 237.262 1.00 78.99  ? 330 THR A CB  1 
ATOM   2484  O  OG1 . THR A 1 330 ? 206.679 206.163 237.206 1.00 82.43  ? 330 THR A OG1 1 
ATOM   2485  C  CG2 . THR A 1 330 ? 205.591 204.501 238.561 1.00 78.84  ? 330 THR A CG2 1 
ATOM   2486  N  N   . ILE A 1 331 ? 209.277 203.813 235.434 1.00 71.03  ? 331 ILE A N   1 
ATOM   2487  C  CA  . ILE A 1 331 ? 210.218 204.371 234.475 1.00 71.64  ? 331 ILE A CA  1 
ATOM   2488  C  C   . ILE A 1 331 ? 209.489 205.347 233.566 1.00 78.53  ? 331 ILE A C   1 
ATOM   2489  O  O   . ILE A 1 331 ? 208.374 205.080 233.104 1.00 81.47  ? 331 ILE A O   1 
ATOM   2490  C  CB  . ILE A 1 331 ? 210.884 203.244 233.670 1.00 69.31  ? 331 ILE A CB  1 
ATOM   2491  C  CG1 . ILE A 1 331 ? 211.668 202.311 234.588 1.00 67.09  ? 331 ILE A CG1 1 
ATOM   2492  C  CG2 . ILE A 1 331 ? 211.780 203.803 232.603 1.00 70.44  ? 331 ILE A CG2 1 
ATOM   2493  C  CD1 . ILE A 1 331 ? 211.811 200.919 234.041 1.00 64.70  ? 331 ILE A CD1 1 
ATOM   2494  N  N   . ARG A 1 332 ? 210.113 206.491 233.305 1.00 77.83  ? 332 ARG A N   1 
ATOM   2495  C  CA  . ARG A 1 332 ? 209.509 207.537 232.498 1.00 80.14  ? 332 ARG A CA  1 
ATOM   2496  C  C   . ARG A 1 332 ? 210.375 207.808 231.276 1.00 84.71  ? 332 ARG A C   1 
ATOM   2497  O  O   . ARG A 1 332 ? 211.604 207.711 231.334 1.00 84.67  ? 332 ARG A O   1 
ATOM   2498  C  CB  . ARG A 1 332 ? 209.327 208.818 233.311 1.00 83.44  ? 332 ARG A CB  1 
ATOM   2499  C  CG  . ARG A 1 332 ? 208.728 208.570 234.677 1.00 87.05  ? 332 ARG A CG  1 
ATOM   2500  C  CD  . ARG A 1 332 ? 207.421 209.310 234.873 1.00 94.73  ? 332 ARG A CD  1 
ATOM   2501  N  NE  . ARG A 1 332 ? 206.663 208.762 235.992 1.00 97.04  ? 332 ARG A NE  1 
ATOM   2502  C  CZ  . ARG A 1 332 ? 205.529 209.270 236.454 1.00 96.77  ? 332 ARG A CZ  1 
ATOM   2503  N  NH1 . ARG A 1 332 ? 204.989 210.353 235.921 1.00 95.30  ? 332 ARG A NH1 1 
ATOM   2504  N  NH2 . ARG A 1 332 ? 204.923 208.677 237.478 1.00 93.89  ? 332 ARG A NH2 1 
ATOM   2505  N  N   . GLN A 1 333 ? 209.723 208.148 230.166 1.00 86.86  ? 333 GLN A N   1 
ATOM   2506  C  CA  . GLN A 1 333 ? 210.425 208.371 228.911 1.00 88.08  ? 333 GLN A CA  1 
ATOM   2507  C  C   . GLN A 1 333 ? 211.180 209.698 228.946 1.00 91.69  ? 333 GLN A C   1 
ATOM   2508  O  O   . GLN A 1 333 ? 211.141 210.448 229.925 1.00 92.65  ? 333 GLN A O   1 
ATOM   2509  C  CB  . GLN A 1 333 ? 209.447 208.346 227.741 1.00 88.83  ? 333 GLN A CB  1 
ATOM   2510  C  CG  . GLN A 1 333 ? 209.149 206.958 227.205 1.00 91.55  ? 333 GLN A CG  1 
ATOM   2511  C  CD  . GLN A 1 333 ? 208.304 206.989 225.946 1.00 93.06  ? 333 GLN A CD  1 
ATOM   2512  O  OE1 . GLN A 1 333 ? 208.527 207.807 225.054 1.00 90.86  ? 333 GLN A OE1 1 
ATOM   2513  N  NE2 . GLN A 1 333 ? 207.326 206.094 225.869 1.00 90.29  ? 333 GLN A NE2 1 
ATOM   2514  N  N   . ARG A 1 334 ? 211.876 209.989 227.842 1.00 93.16  ? 334 ARG A N   1 
ATOM   2515  C  CA  . ARG A 1 334 ? 212.617 211.243 227.741 1.00 96.34  ? 334 ARG A CA  1 
ATOM   2516  C  C   . ARG A 1 334 ? 211.686 212.441 227.847 1.00 97.82  ? 334 ARG A C   1 
ATOM   2517  O  O   . ARG A 1 334 ? 211.990 213.413 228.549 1.00 95.89  ? 334 ARG A O   1 
ATOM   2518  C  CB  . ARG A 1 334 ? 213.398 211.288 226.429 1.00 95.15  ? 334 ARG A CB  1 
ATOM   2519  C  CG  . ARG A 1 334 ? 214.042 212.633 226.147 1.00 94.25  ? 334 ARG A CG  1 
ATOM   2520  C  CD  . ARG A 1 334 ? 215.185 212.919 227.103 1.00 91.96  ? 334 ARG A CD  1 
ATOM   2521  N  NE  . ARG A 1 334 ? 215.914 214.124 226.726 1.00 92.70  ? 334 ARG A NE  1 
ATOM   2522  C  CZ  . ARG A 1 334 ? 216.957 214.607 227.387 1.00 89.78  ? 334 ARG A CZ  1 
ATOM   2523  N  NH1 . ARG A 1 334 ? 217.425 214.010 228.471 1.00 88.33  ? 334 ARG A NH1 1 
ATOM   2524  N  NH2 . ARG A 1 334 ? 217.544 215.718 226.951 1.00 82.74  ? 334 ARG A NH2 1 
ATOM   2525  N  N   . ASP A 1 335 ? 210.546 212.392 227.159 1.00 98.69  ? 335 ASP A N   1 
ATOM   2526  C  CA  . ASP A 1 335 ? 209.520 213.404 227.362 1.00 93.32  ? 335 ASP A CA  1 
ATOM   2527  C  C   . ASP A 1 335 ? 208.826 213.245 228.703 1.00 91.77  ? 335 ASP A C   1 
ATOM   2528  O  O   . ASP A 1 335 ? 208.457 214.249 229.319 1.00 92.90  ? 335 ASP A O   1 
ATOM   2529  C  CB  . ASP A 1 335 ? 208.485 213.348 226.238 1.00 93.17  ? 335 ASP A CB  1 
ATOM   2530  C  CG  . ASP A 1 335 ? 207.906 211.961 226.045 1.00 96.74  ? 335 ASP A CG  1 
ATOM   2531  O  OD1 . ASP A 1 335 ? 208.183 211.077 226.881 1.00 94.23  ? 335 ASP A OD1 1 
ATOM   2532  O  OD2 . ASP A 1 335 ? 207.171 211.754 225.058 1.00 99.92  ? 335 ASP A OD2 1 
ATOM   2533  N  N   . GLY A 1 336 ? 208.647 212.013 229.164 1.00 91.61  ? 336 GLY A N   1 
ATOM   2534  C  CA  . GLY A 1 336 ? 208.025 211.742 230.446 1.00 91.30  ? 336 GLY A CA  1 
ATOM   2535  C  C   . GLY A 1 336 ? 206.900 210.730 230.408 1.00 89.89  ? 336 GLY A C   1 
ATOM   2536  O  O   . GLY A 1 336 ? 206.388 210.364 231.475 1.00 91.44  ? 336 GLY A O   1 
ATOM   2537  N  N   . ALA A 1 337 ? 206.482 210.263 229.237 1.00 89.28  ? 337 ALA A N   1 
ATOM   2538  C  CA  . ALA A 1 337 ? 205.415 209.279 229.186 1.00 86.55  ? 337 ALA A CA  1 
ATOM   2539  C  C   . ALA A 1 337 ? 205.891 207.965 229.798 1.00 84.56  ? 337 ALA A C   1 
ATOM   2540  O  O   . ALA A 1 337 ? 206.978 207.486 229.468 1.00 85.97  ? 337 ALA A O   1 
ATOM   2541  C  CB  . ALA A 1 337 ? 204.959 209.054 227.746 1.00 85.36  ? 337 ALA A CB  1 
ATOM   2542  N  N   . PRO A 1 338 ? 205.105 207.362 230.687 1.00 79.29  ? 338 PRO A N   1 
ATOM   2543  C  CA  . PRO A 1 338 ? 205.568 206.158 231.385 1.00 79.27  ? 338 PRO A CA  1 
ATOM   2544  C  C   . PRO A 1 338 ? 205.893 205.037 230.414 1.00 81.34  ? 338 PRO A C   1 
ATOM   2545  O  O   . PRO A 1 338 ? 205.181 204.811 229.435 1.00 83.70  ? 338 PRO A O   1 
ATOM   2546  C  CB  . PRO A 1 338 ? 204.387 205.795 232.292 1.00 77.87  ? 338 PRO A CB  1 
ATOM   2547  C  CG  . PRO A 1 338 ? 203.226 206.546 231.748 1.00 79.51  ? 338 PRO A CG  1 
ATOM   2548  C  CD  . PRO A 1 338 ? 203.777 207.789 231.146 1.00 76.80  ? 338 PRO A CD  1 
ATOM   2549  N  N   . ALA A 1 339 ? 206.975 204.320 230.706 1.00 80.40  ? 339 ALA A N   1 
ATOM   2550  C  CA  . ALA A 1 339 ? 207.510 203.339 229.773 1.00 83.63  ? 339 ALA A CA  1 
ATOM   2551  C  C   . ALA A 1 339 ? 207.857 201.994 230.387 1.00 85.52  ? 339 ALA A C   1 
ATOM   2552  O  O   . ALA A 1 339 ? 208.079 201.047 229.628 1.00 86.24  ? 339 ALA A O   1 
ATOM   2553  C  CB  . ALA A 1 339 ? 208.763 203.894 229.081 1.00 79.60  ? 339 ALA A CB  1 
ATOM   2554  N  N   . GLY A 1 340 ? 207.921 201.858 231.704 1.00 82.91  ? 340 GLY A N   1 
ATOM   2555  C  CA  . GLY A 1 340 ? 208.278 200.576 232.275 1.00 79.81  ? 340 GLY A CA  1 
ATOM   2556  C  C   . GLY A 1 340 ? 208.047 200.530 233.766 1.00 74.67  ? 340 GLY A C   1 
ATOM   2557  O  O   . GLY A 1 340 ? 207.970 201.563 234.439 1.00 76.12  ? 340 GLY A O   1 
ATOM   2558  N  N   . ILE A 1 341 ? 207.948 199.307 234.268 1.00 68.54  ? 341 ILE A N   1 
ATOM   2559  C  CA  . ILE A 1 341 ? 207.879 199.018 235.694 1.00 68.03  ? 341 ILE A CA  1 
ATOM   2560  C  C   . ILE A 1 341 ? 209.121 198.235 236.087 1.00 67.70  ? 341 ILE A C   1 
ATOM   2561  O  O   . ILE A 1 341 ? 209.519 197.294 235.393 1.00 72.09  ? 341 ILE A O   1 
ATOM   2562  C  CB  . ILE A 1 341 ? 206.605 198.231 236.055 1.00 72.93  ? 341 ILE A CB  1 
ATOM   2563  C  CG1 . ILE A 1 341 ? 205.344 199.080 235.872 1.00 71.69  ? 341 ILE A CG1 1 
ATOM   2564  C  CG2 . ILE A 1 341 ? 206.682 197.713 237.483 1.00 71.88  ? 341 ILE A CG2 1 
ATOM   2565  C  CD1 . ILE A 1 341 ? 205.544 200.557 236.042 1.00 70.50  ? 341 ILE A CD1 1 
ATOM   2566  N  N   . LEU A 1 342 ? 209.747 198.633 237.190 1.00 61.51  ? 342 LEU A N   1 
ATOM   2567  C  CA  . LEU A 1 342 ? 210.877 197.915 237.763 1.00 58.70  ? 342 LEU A CA  1 
ATOM   2568  C  C   . LEU A 1 342 ? 210.493 197.454 239.159 1.00 64.80  ? 342 LEU A C   1 
ATOM   2569  O  O   . LEU A 1 342 ? 210.138 198.281 240.006 1.00 71.53  ? 342 LEU A O   1 
ATOM   2570  C  CB  . LEU A 1 342 ? 212.124 198.804 237.813 1.00 47.49  ? 342 LEU A CB  1 
ATOM   2571  C  CG  . LEU A 1 342 ? 213.415 198.273 238.424 1.00 45.00  ? 342 LEU A CG  1 
ATOM   2572  C  CD1 . LEU A 1 342 ? 214.614 198.912 237.788 1.00 47.21  ? 342 LEU A CD1 1 
ATOM   2573  C  CD2 . LEU A 1 342 ? 213.456 198.531 239.904 1.00 50.78  ? 342 LEU A CD2 1 
ATOM   2574  N  N   . GLN A 1 343 ? 210.554 196.145 239.409 1.00 61.43  ? 343 GLN A N   1 
ATOM   2575  C  CA  . GLN A 1 343 ? 210.249 195.639 240.740 1.00 60.19  ? 343 GLN A CA  1 
ATOM   2576  C  C   . GLN A 1 343 ? 211.418 194.838 241.295 1.00 65.41  ? 343 GLN A C   1 
ATOM   2577  O  O   . GLN A 1 343 ? 211.877 193.878 240.672 1.00 73.10  ? 343 GLN A O   1 
ATOM   2578  C  CB  . GLN A 1 343 ? 208.963 194.798 240.763 1.00 62.75  ? 343 GLN A CB  1 
ATOM   2579  C  CG  . GLN A 1 343 ? 208.798 193.665 239.740 1.00 70.58  ? 343 GLN A CG  1 
ATOM   2580  C  CD  . GLN A 1 343 ? 208.767 194.105 238.285 1.00 71.13  ? 343 GLN A CD  1 
ATOM   2581  O  OE1 . GLN A 1 343 ? 209.037 195.256 237.955 1.00 69.25  ? 343 GLN A OE1 1 
ATOM   2582  N  NE2 . GLN A 1 343 ? 208.405 193.182 237.407 1.00 71.40  ? 343 GLN A NE2 1 
ATOM   2583  N  N   . ILE A 1 344 ? 211.874 195.231 242.483 1.00 64.98  ? 344 ILE A N   1 
ATOM   2584  C  CA  . ILE A 1 344 ? 212.984 194.605 243.193 1.00 71.90  ? 344 ILE A CA  1 
ATOM   2585  C  C   . ILE A 1 344 ? 212.442 194.020 244.486 1.00 84.55  ? 344 ILE A C   1 
ATOM   2586  O  O   . ILE A 1 344 ? 211.720 194.703 245.221 1.00 88.71  ? 344 ILE A O   1 
ATOM   2587  C  CB  . ILE A 1 344 ? 214.100 195.618 243.505 1.00 68.41  ? 344 ILE A CB  1 
ATOM   2588  C  CG1 . ILE A 1 344 ? 214.834 196.036 242.237 1.00 70.47  ? 344 ILE A CG1 1 
ATOM   2589  C  CG2 . ILE A 1 344 ? 215.063 195.061 244.527 1.00 70.62  ? 344 ILE A CG2 1 
ATOM   2590  C  CD1 . ILE A 1 344 ? 215.634 197.308 242.405 1.00 70.51  ? 344 ILE A CD1 1 
ATOM   2591  N  N   . LYS A 1 345 ? 212.785 192.765 244.769 1.00 87.72  ? 345 LYS A N   1 
ATOM   2592  C  CA  . LYS A 1 345 ? 212.412 192.120 246.019 1.00 84.18  ? 345 LYS A CA  1 
ATOM   2593  C  C   . LYS A 1 345 ? 213.659 191.620 246.729 1.00 84.53  ? 345 LYS A C   1 
ATOM   2594  O  O   . LYS A 1 345 ? 214.456 190.883 246.144 1.00 83.01  ? 345 LYS A O   1 
ATOM   2595  C  CB  . LYS A 1 345 ? 211.432 190.975 245.775 1.00 81.35  ? 345 LYS A CB  1 
ATOM   2596  C  CG  . LYS A 1 345 ? 210.186 191.401 245.028 1.00 82.32  ? 345 LYS A CG  1 
ATOM   2597  C  CD  . LYS A 1 345 ? 209.715 190.344 244.045 1.00 90.59  ? 345 LYS A CD  1 
ATOM   2598  C  CE  . LYS A 1 345 ? 210.777 190.017 243.016 1.00 90.14  ? 345 LYS A CE  1 
ATOM   2599  N  NZ  . LYS A 1 345 ? 210.276 189.033 242.020 1.00 87.06  ? 345 LYS A NZ  1 
ATOM   2600  N  N   . THR A 1 346 ? 213.819 192.022 247.987 1.00 90.22  ? 346 THR A N   1 
ATOM   2601  C  CA  . THR A 1 346 ? 214.943 191.617 248.815 1.00 94.89  ? 346 THR A CA  1 
ATOM   2602  C  C   . THR A 1 346 ? 214.428 191.069 250.137 1.00 99.66  ? 346 THR A C   1 
ATOM   2603  O  O   . THR A 1 346 ? 213.336 191.424 250.589 1.00 100.21 ? 346 THR A O   1 
ATOM   2604  C  CB  . THR A 1 346 ? 215.893 192.778 249.101 1.00 93.57  ? 346 THR A CB  1 
ATOM   2605  O  OG1 . THR A 1 346 ? 215.260 193.698 249.999 1.00 96.37  ? 346 THR A OG1 1 
ATOM   2606  C  CG2 . THR A 1 346 ? 216.239 193.505 247.821 1.00 90.86  ? 346 THR A CG2 1 
ATOM   2607  N  N   . SER A 1 347 ? 215.228 190.202 250.754 1.00 102.97 ? 347 SER A N   1 
ATOM   2608  C  CA  . SER A 1 347 ? 214.862 189.642 252.047 1.00 107.30 ? 347 SER A CA  1 
ATOM   2609  C  C   . SER A 1 347 ? 214.847 190.733 253.108 1.00 108.01 ? 347 SER A C   1 
ATOM   2610  O  O   . SER A 1 347 ? 215.748 191.572 253.169 1.00 106.54 ? 347 SER A O   1 
ATOM   2611  C  CB  . SER A 1 347 ? 215.840 188.536 252.443 1.00 110.27 ? 347 SER A CB  1 
ATOM   2612  O  OG  . SER A 1 347 ? 217.182 188.959 252.276 1.00 114.01 ? 347 SER A OG  1 
ATOM   2613  N  N   . SER A 1 348 ? 213.822 190.711 253.952 1.00 110.24 ? 348 SER A N   1 
ATOM   2614  C  CA  . SER A 1 348 ? 213.628 191.784 254.916 1.00 109.58 ? 348 SER A CA  1 
ATOM   2615  C  C   . SER A 1 348 ? 214.762 191.821 255.933 1.00 104.15 ? 348 SER A C   1 
ATOM   2616  O  O   . SER A 1 348 ? 215.278 190.788 256.365 1.00 102.36 ? 348 SER A O   1 
ATOM   2617  C  CB  . SER A 1 348 ? 212.291 191.625 255.638 1.00 110.94 ? 348 SER A CB  1 
ATOM   2618  O  OG  . SER A 1 348 ? 211.967 192.799 256.362 1.00 106.04 ? 348 SER A OG  1 
ATOM   2619  N  N   . GLY A 1 349 ? 215.155 193.035 256.304 1.00 100.23 ? 349 GLY A N   1 
ATOM   2620  C  CA  . GLY A 1 349 ? 216.169 193.240 257.311 1.00 99.26  ? 349 GLY A CA  1 
ATOM   2621  C  C   . GLY A 1 349 ? 217.588 193.263 256.795 1.00 97.09  ? 349 GLY A C   1 
ATOM   2622  O  O   . GLY A 1 349 ? 218.501 193.600 257.559 1.00 99.43  ? 349 GLY A O   1 
ATOM   2623  N  N   . ALA A 1 350 ? 217.808 192.919 255.529 1.00 94.59  ? 350 ALA A N   1 
ATOM   2624  C  CA  . ALA A 1 350 ? 219.162 192.954 254.991 1.00 91.91  ? 350 ALA A CA  1 
ATOM   2625  C  C   . ALA A 1 350 ? 219.617 194.384 254.738 1.00 91.84  ? 350 ALA A C   1 
ATOM   2626  O  O   . ALA A 1 350 ? 220.758 194.743 255.053 1.00 93.28  ? 350 ALA A O   1 
ATOM   2627  C  CB  . ALA A 1 350 ? 219.239 192.128 253.707 1.00 93.49  ? 350 ALA A CB  1 
ATOM   2628  N  N   . GLU A 1 351 ? 218.742 195.215 254.174 1.00 89.29  ? 351 GLU A N   1 
ATOM   2629  C  CA  . GLU A 1 351 ? 219.068 196.594 253.851 1.00 80.54  ? 351 GLU A CA  1 
ATOM   2630  C  C   . GLU A 1 351 ? 217.962 197.512 254.346 1.00 70.84  ? 351 GLU A C   1 
ATOM   2631  O  O   . GLU A 1 351 ? 216.798 197.118 254.431 1.00 73.33  ? 351 GLU A O   1 
ATOM   2632  C  CB  . GLU A 1 351 ? 219.262 196.786 252.346 1.00 79.40  ? 351 GLU A CB  1 
ATOM   2633  C  CG  . GLU A 1 351 ? 220.019 195.661 251.666 1.00 86.04  ? 351 GLU A CG  1 
ATOM   2634  C  CD  . GLU A 1 351 ? 221.507 195.698 251.957 1.00 95.32  ? 351 GLU A CD  1 
ATOM   2635  O  OE1 . GLU A 1 351 ? 222.002 196.755 252.400 1.00 94.15  ? 351 GLU A OE1 1 
ATOM   2636  O  OE2 . GLU A 1 351 ? 222.181 194.668 251.744 1.00 98.73  ? 351 GLU A OE2 1 
ATOM   2637  N  N   . THR A 1 352 ? 218.338 198.748 254.657 1.00 63.10  ? 352 THR A N   1 
ATOM   2638  C  CA  . THR A 1 352 ? 217.377 199.728 255.127 1.00 57.50  ? 352 THR A CA  1 
ATOM   2639  C  C   . THR A 1 352 ? 216.515 200.211 253.970 1.00 56.21  ? 352 THR A C   1 
ATOM   2640  O  O   . THR A 1 352 ? 216.706 199.833 252.812 1.00 59.08  ? 352 THR A O   1 
ATOM   2641  C  CB  . THR A 1 352 ? 218.084 200.917 255.766 1.00 59.25  ? 352 THR A CB  1 
ATOM   2642  O  OG1 . THR A 1 352 ? 218.489 201.830 254.742 1.00 59.61  ? 352 THR A OG1 1 
ATOM   2643  C  CG2 . THR A 1 352 ? 219.313 200.452 256.516 1.00 65.15  ? 352 THR A CG2 1 
ATOM   2644  N  N   . SER A 1 353 ? 215.547 201.062 254.296 1.00 52.76  ? 353 SER A N   1 
ATOM   2645  C  CA  . SER A 1 353 ? 214.692 201.614 253.255 1.00 55.99  ? 353 SER A CA  1 
ATOM   2646  C  C   . SER A 1 353 ? 215.476 202.535 252.329 1.00 57.82  ? 353 SER A C   1 
ATOM   2647  O  O   . SER A 1 353 ? 215.255 202.538 251.111 1.00 62.41  ? 353 SER A O   1 
ATOM   2648  C  CB  . SER A 1 353 ? 213.519 202.355 253.887 1.00 60.93  ? 353 SER A CB  1 
ATOM   2649  O  OG  . SER A 1 353 ? 212.684 202.923 252.895 1.00 71.86  ? 353 SER A OG  1 
ATOM   2650  N  N   . ALA A 1 354 ? 216.400 203.318 252.889 1.00 53.86  ? 354 ALA A N   1 
ATOM   2651  C  CA  . ALA A 1 354 ? 217.088 204.338 252.106 1.00 55.76  ? 354 ALA A CA  1 
ATOM   2652  C  C   . ALA A 1 354 ? 217.928 203.727 250.998 1.00 54.12  ? 354 ALA A C   1 
ATOM   2653  O  O   . ALA A 1 354 ? 217.914 204.212 249.862 1.00 56.94  ? 354 ALA A O   1 
ATOM   2654  C  CB  . ALA A 1 354 ? 217.958 205.199 253.019 1.00 59.31  ? 354 ALA A CB  1 
ATOM   2655  N  N   . PHE A 1 355 ? 218.671 202.668 251.303 1.00 51.80  ? 355 PHE A N   1 
ATOM   2656  C  CA  . PHE A 1 355 ? 219.543 202.076 250.298 1.00 50.43  ? 355 PHE A CA  1 
ATOM   2657  C  C   . PHE A 1 355 ? 218.746 201.454 249.162 1.00 51.73  ? 355 PHE A C   1 
ATOM   2658  O  O   . PHE A 1 355 ? 219.117 201.589 247.991 1.00 57.50  ? 355 PHE A O   1 
ATOM   2659  C  CB  . PHE A 1 355 ? 220.447 201.039 250.940 1.00 55.91  ? 355 PHE A CB  1 
ATOM   2660  C  CG  . PHE A 1 355 ? 221.613 200.662 250.103 1.00 61.06  ? 355 PHE A CG  1 
ATOM   2661  C  CD1 . PHE A 1 355 ? 222.455 201.625 249.594 1.00 62.24  ? 355 PHE A CD1 1 
ATOM   2662  C  CD2 . PHE A 1 355 ? 221.881 199.339 249.832 1.00 68.75  ? 355 PHE A CD2 1 
ATOM   2663  C  CE1 . PHE A 1 355 ? 223.539 201.275 248.825 1.00 69.32  ? 355 PHE A CE1 1 
ATOM   2664  C  CE2 . PHE A 1 355 ? 222.962 198.984 249.062 1.00 74.62  ? 355 PHE A CE2 1 
ATOM   2665  C  CZ  . PHE A 1 355 ? 223.792 199.953 248.558 1.00 75.61  ? 355 PHE A CZ  1 
ATOM   2666  N  N   . ILE A 1 356 ? 217.649 200.773 249.486 1.00 49.99  ? 356 ILE A N   1 
ATOM   2667  C  CA  . ILE A 1 356 ? 216.827 200.172 248.447 1.00 48.92  ? 356 ILE A CA  1 
ATOM   2668  C  C   . ILE A 1 356 ? 216.179 201.250 247.592 1.00 54.87  ? 356 ILE A C   1 
ATOM   2669  O  O   . ILE A 1 356 ? 216.097 201.120 246.366 1.00 58.73  ? 356 ILE A O   1 
ATOM   2670  C  CB  . ILE A 1 356 ? 215.787 199.223 249.061 1.00 50.61  ? 356 ILE A CB  1 
ATOM   2671  C  CG1 . ILE A 1 356 ? 216.490 198.104 249.815 1.00 60.51  ? 356 ILE A CG1 1 
ATOM   2672  C  CG2 . ILE A 1 356 ? 214.929 198.622 247.985 1.00 57.04  ? 356 ILE A CG2 1 
ATOM   2673  C  CD1 . ILE A 1 356 ? 215.585 197.343 250.749 1.00 65.86  ? 356 ILE A CD1 1 
ATOM   2674  N  N   . GLU A 1 357 ? 215.715 202.335 248.214 1.00 55.48  ? 357 GLU A N   1 
ATOM   2675  C  CA  . GLU A 1 357 ? 215.134 203.417 247.427 1.00 53.67  ? 357 GLU A CA  1 
ATOM   2676  C  C   . GLU A 1 357 ? 216.174 204.058 246.512 1.00 53.05  ? 357 GLU A C   1 
ATOM   2677  O  O   . GLU A 1 357 ? 215.877 204.402 245.362 1.00 56.19  ? 357 GLU A O   1 
ATOM   2678  C  CB  . GLU A 1 357 ? 214.512 204.464 248.340 1.00 53.76  ? 357 GLU A CB  1 
ATOM   2679  C  CG  . GLU A 1 357 ? 213.770 205.530 247.586 1.00 59.39  ? 357 GLU A CG  1 
ATOM   2680  C  CD  . GLU A 1 357 ? 214.629 206.733 247.274 1.00 67.71  ? 357 GLU A CD  1 
ATOM   2681  O  OE1 . GLU A 1 357 ? 215.755 206.815 247.806 1.00 69.56  ? 357 GLU A OE1 1 
ATOM   2682  O  OE2 . GLU A 1 357 ? 214.183 207.593 246.487 1.00 70.59  ? 357 GLU A OE2 1 
ATOM   2683  N  N   . ARG A 1 358 ? 217.397 204.229 247.008 1.00 51.84  ? 358 ARG A N   1 
ATOM   2684  C  CA  . ARG A 1 358 ? 218.450 204.819 246.193 1.00 48.04  ? 358 ARG A CA  1 
ATOM   2685  C  C   . ARG A 1 358 ? 218.794 203.933 245.004 1.00 52.27  ? 358 ARG A C   1 
ATOM   2686  O  O   . ARG A 1 358 ? 218.981 204.429 243.883 1.00 60.06  ? 358 ARG A O   1 
ATOM   2687  C  CB  . ARG A 1 358 ? 219.687 205.069 247.042 1.00 49.45  ? 358 ARG A CB  1 
ATOM   2688  C  CG  . ARG A 1 358 ? 220.744 205.878 246.359 1.00 53.70  ? 358 ARG A CG  1 
ATOM   2689  C  CD  . ARG A 1 358 ? 221.896 206.119 247.298 1.00 61.82  ? 358 ARG A CD  1 
ATOM   2690  N  NE  . ARG A 1 358 ? 221.460 206.693 248.561 1.00 66.17  ? 358 ARG A NE  1 
ATOM   2691  C  CZ  . ARG A 1 358 ? 221.926 207.828 249.060 1.00 69.35  ? 358 ARG A CZ  1 
ATOM   2692  N  NH1 . ARG A 1 358 ? 222.862 208.523 248.436 1.00 70.98  ? 358 ARG A NH1 1 
ATOM   2693  N  NH2 . ARG A 1 358 ? 221.446 208.274 250.217 1.00 72.53  ? 358 ARG A NH2 1 
ATOM   2694  N  N   . VAL A 1 359 ? 218.916 202.620 245.228 1.00 50.09  ? 359 VAL A N   1 
ATOM   2695  C  CA  . VAL A 1 359 ? 219.227 201.762 244.091 1.00 48.59  ? 359 VAL A CA  1 
ATOM   2696  C  C   . VAL A 1 359 ? 218.060 201.747 243.128 1.00 48.76  ? 359 VAL A C   1 
ATOM   2697  O  O   . VAL A 1 359 ? 218.259 201.695 241.910 1.00 56.65  ? 359 VAL A O   1 
ATOM   2698  C  CB  . VAL A 1 359 ? 219.628 200.331 244.504 1.00 53.55  ? 359 VAL A CB  1 
ATOM   2699  C  CG1 . VAL A 1 359 ? 221.037 200.294 245.066 1.00 57.88  ? 359 VAL A CG1 1 
ATOM   2700  C  CG2 . VAL A 1 359 ? 218.648 199.738 245.476 1.00 58.37  ? 359 VAL A CG2 1 
ATOM   2701  N  N   . ALA A 1 360 ? 216.831 201.823 243.634 1.00 46.39  ? 360 ALA A N   1 
ATOM   2702  C  CA  . ALA A 1 360 ? 215.685 201.896 242.739 1.00 50.04  ? 360 ALA A CA  1 
ATOM   2703  C  C   . ALA A 1 360 ? 215.765 203.128 241.854 1.00 52.63  ? 360 ALA A C   1 
ATOM   2704  O  O   . ALA A 1 360 ? 215.506 203.059 240.651 1.00 54.56  ? 360 ALA A O   1 
ATOM   2705  C  CB  . ALA A 1 360 ? 214.389 201.900 243.544 1.00 52.49  ? 360 ALA A CB  1 
ATOM   2706  N  N   . ASP A 1 361 ? 216.150 204.264 242.431 1.00 53.62  ? 361 ASP A N   1 
ATOM   2707  C  CA  . ASP A 1 361 ? 216.216 205.509 241.670 1.00 52.98  ? 361 ASP A CA  1 
ATOM   2708  C  C   . ASP A 1 361 ? 217.301 205.454 240.599 1.00 49.06  ? 361 ASP A C   1 
ATOM   2709  O  O   . ASP A 1 361 ? 217.054 205.750 239.415 1.00 55.84  ? 361 ASP A O   1 
ATOM   2710  C  CB  . ASP A 1 361 ? 216.480 206.657 242.635 1.00 60.19  ? 361 ASP A CB  1 
ATOM   2711  C  CG  . ASP A 1 361 ? 215.271 207.518 242.853 1.00 68.92  ? 361 ASP A CG  1 
ATOM   2712  O  OD1 . ASP A 1 361 ? 215.448 208.711 243.157 1.00 71.07  ? 361 ASP A OD1 1 
ATOM   2713  O  OD2 . ASP A 1 361 ? 214.147 207.000 242.721 1.00 72.05  ? 361 ASP A OD2 1 
ATOM   2714  N  N   . ILE A 1 362 ? 218.514 205.083 241.006 1.00 42.77  ? 362 ILE A N   1 
ATOM   2715  C  CA  . ILE A 1 362 ? 219.619 204.979 240.060 1.00 45.46  ? 362 ILE A CA  1 
ATOM   2716  C  C   . ILE A 1 362 ? 219.289 203.996 238.947 1.00 52.97  ? 362 ILE A C   1 
ATOM   2717  O  O   . ILE A 1 362 ? 219.573 204.250 237.770 1.00 57.70  ? 362 ILE A O   1 
ATOM   2718  C  CB  . ILE A 1 362 ? 220.906 204.579 240.797 1.00 47.45  ? 362 ILE A CB  1 
ATOM   2719  C  CG1 . ILE A 1 362 ? 221.506 205.783 241.520 1.00 53.68  ? 362 ILE A CG1 1 
ATOM   2720  C  CG2 . ILE A 1 362 ? 221.868 203.905 239.851 1.00 53.10  ? 362 ILE A CG2 1 
ATOM   2721  C  CD1 . ILE A 1 362 ? 221.448 207.067 240.726 1.00 60.50  ? 362 ILE A CD1 1 
ATOM   2722  N  N   . SER A 1 363 ? 218.685 202.858 239.292 1.00 51.24  ? 363 SER A N   1 
ATOM   2723  C  CA  . SER A 1 363 ? 218.345 201.873 238.278 1.00 48.19  ? 363 SER A CA  1 
ATOM   2724  C  C   . SER A 1 363 ? 217.225 202.355 237.373 1.00 48.91  ? 363 SER A C   1 
ATOM   2725  O  O   . SER A 1 363 ? 217.198 202.003 236.191 1.00 54.28  ? 363 SER A O   1 
ATOM   2726  C  CB  . SER A 1 363 ? 217.953 200.562 238.943 1.00 52.36  ? 363 SER A CB  1 
ATOM   2727  O  OG  . SER A 1 363 ? 218.889 200.205 239.941 1.00 57.11  ? 363 SER A OG  1 
ATOM   2728  N  N   . GLN A 1 364 ? 216.286 203.135 237.902 1.00 44.98  ? 364 GLN A N   1 
ATOM   2729  C  CA  . GLN A 1 364 ? 215.196 203.629 237.073 1.00 45.27  ? 364 GLN A CA  1 
ATOM   2730  C  C   . GLN A 1 364 ? 215.713 204.569 236.002 1.00 52.03  ? 364 GLN A C   1 
ATOM   2731  O  O   . GLN A 1 364 ? 215.286 204.501 234.842 1.00 58.22  ? 364 GLN A O   1 
ATOM   2732  C  CB  . GLN A 1 364 ? 214.161 204.315 237.955 1.00 44.20  ? 364 GLN A CB  1 
ATOM   2733  C  CG  . GLN A 1 364 ? 213.280 205.279 237.230 1.00 52.27  ? 364 GLN A CG  1 
ATOM   2734  C  CD  . GLN A 1 364 ? 212.684 206.308 238.162 1.00 63.27  ? 364 GLN A CD  1 
ATOM   2735  O  OE1 . GLN A 1 364 ? 213.320 207.308 238.487 1.00 63.26  ? 364 GLN A OE1 1 
ATOM   2736  N  NE2 . GLN A 1 364 ? 211.458 206.066 238.605 1.00 68.89  ? 364 GLN A NE2 1 
ATOM   2737  N  N   . HIS A 1 365 ? 216.653 205.438 236.364 1.00 52.01  ? 365 HIS A N   1 
ATOM   2738  C  CA  . HIS A 1 365 ? 217.214 206.320 235.342 1.00 52.92  ? 365 HIS A CA  1 
ATOM   2739  C  C   . HIS A 1 365 ? 217.892 205.530 234.223 1.00 53.21  ? 365 HIS A C   1 
ATOM   2740  O  O   . HIS A 1 365 ? 217.676 205.817 233.035 1.00 57.64  ? 365 HIS A O   1 
ATOM   2741  C  CB  . HIS A 1 365 ? 218.200 207.295 235.972 1.00 58.72  ? 365 HIS A CB  1 
ATOM   2742  C  CG  . HIS A 1 365 ? 218.812 208.245 234.993 1.00 67.25  ? 365 HIS A CG  1 
ATOM   2743  N  ND1 . HIS A 1 365 ? 220.095 208.101 234.516 1.00 71.27  ? 365 HIS A ND1 1 
ATOM   2744  C  CD2 . HIS A 1 365 ? 218.308 209.348 234.393 1.00 70.59  ? 365 HIS A CD2 1 
ATOM   2745  C  CE1 . HIS A 1 365 ? 220.361 209.081 233.673 1.00 72.51  ? 365 HIS A CE1 1 
ATOM   2746  N  NE2 . HIS A 1 365 ? 219.291 209.848 233.575 1.00 71.13  ? 365 HIS A NE2 1 
ATOM   2747  N  N   . MET A 1 366 ? 218.678 204.513 234.573 1.00 51.73  ? 366 MET A N   1 
ATOM   2748  C  CA  . MET A 1 366 ? 219.400 203.751 233.562 1.00 52.02  ? 366 MET A CA  1 
ATOM   2749  C  C   . MET A 1 366 ? 218.459 202.896 232.723 1.00 52.35  ? 366 MET A C   1 
ATOM   2750  O  O   . MET A 1 366 ? 218.683 202.709 231.519 1.00 58.15  ? 366 MET A O   1 
ATOM   2751  C  CB  . MET A 1 366 ? 220.453 202.884 234.231 1.00 52.29  ? 366 MET A CB  1 
ATOM   2752  C  CG  . MET A 1 366 ? 221.525 203.691 234.871 1.00 57.44  ? 366 MET A CG  1 
ATOM   2753  S  SD  . MET A 1 366 ? 222.782 204.181 233.701 1.00 73.56  ? 366 MET A SD  1 
ATOM   2754  C  CE  . MET A 1 366 ? 223.738 205.254 234.754 1.00 71.89  ? 366 MET A CE  1 
ATOM   2755  N  N   . ALA A 1 367 ? 217.402 202.367 233.332 1.00 48.75  ? 367 ALA A N   1 
ATOM   2756  C  CA  . ALA A 1 367 ? 216.412 201.635 232.561 1.00 50.40  ? 367 ALA A CA  1 
ATOM   2757  C  C   . ALA A 1 367 ? 215.711 202.541 231.560 1.00 52.49  ? 367 ALA A C   1 
ATOM   2758  O  O   . ALA A 1 367 ? 215.438 202.122 230.426 1.00 59.33  ? 367 ALA A O   1 
ATOM   2759  C  CB  . ALA A 1 367 ? 215.401 200.982 233.495 1.00 52.94  ? 367 ALA A CB  1 
ATOM   2760  N  N   . ALA A 1 368 ? 215.408 203.779 231.952 1.00 48.95  ? 368 ALA A N   1 
ATOM   2761  C  CA  . ALA A 1 368 ? 214.842 204.723 230.995 1.00 49.47  ? 368 ALA A CA  1 
ATOM   2762  C  C   . ALA A 1 368 ? 215.817 205.005 229.858 1.00 51.01  ? 368 ALA A C   1 
ATOM   2763  O  O   . ALA A 1 368 ? 215.410 205.137 228.697 1.00 53.81  ? 368 ALA A O   1 
ATOM   2764  C  CB  . ALA A 1 368 ? 214.443 206.014 231.703 1.00 53.03  ? 368 ALA A CB  1 
ATOM   2765  N  N   . LEU A 1 369 ? 217.110 205.101 230.172 1.00 51.75  ? 369 LEU A N   1 
ATOM   2766  C  CA  . LEU A 1 369 ? 218.110 205.252 229.117 1.00 49.97  ? 369 LEU A CA  1 
ATOM   2767  C  C   . LEU A 1 369 ? 218.067 204.087 228.138 1.00 57.43  ? 369 LEU A C   1 
ATOM   2768  O  O   . LEU A 1 369 ? 218.125 204.285 226.915 1.00 64.03  ? 369 LEU A O   1 
ATOM   2769  C  CB  . LEU A 1 369 ? 219.505 205.355 229.726 1.00 47.18  ? 369 LEU A CB  1 
ATOM   2770  C  CG  . LEU A 1 369 ? 219.899 206.652 230.422 1.00 52.68  ? 369 LEU A CG  1 
ATOM   2771  C  CD1 . LEU A 1 369 ? 221.356 206.578 230.813 1.00 56.55  ? 369 LEU A CD1 1 
ATOM   2772  C  CD2 . LEU A 1 369 ? 219.647 207.839 229.525 1.00 55.69  ? 369 LEU A CD2 1 
ATOM   2773  N  N   . ALA A 1 370 ? 217.984 202.861 228.659 1.00 55.18  ? 370 ALA A N   1 
ATOM   2774  C  CA  . ALA A 1 370 ? 217.947 201.689 227.790 1.00 48.02  ? 370 ALA A CA  1 
ATOM   2775  C  C   . ALA A 1 370 ? 216.712 201.700 226.906 1.00 51.77  ? 370 ALA A C   1 
ATOM   2776  O  O   . ALA A 1 370 ? 216.784 201.359 225.720 1.00 55.79  ? 370 ALA A O   1 
ATOM   2777  C  CB  . ALA A 1 370 ? 218.000 200.415 228.624 1.00 47.39  ? 370 ALA A CB  1 
ATOM   2778  N  N   . LEU A 1 371 ? 215.567 202.090 227.462 1.00 53.61  ? 371 LEU A N   1 
ATOM   2779  C  CA  . LEU A 1 371 ? 214.353 202.146 226.657 1.00 52.95  ? 371 LEU A CA  1 
ATOM   2780  C  C   . LEU A 1 371 ? 214.457 203.200 225.565 1.00 57.93  ? 371 LEU A C   1 
ATOM   2781  O  O   . LEU A 1 371 ? 214.023 202.971 224.429 1.00 65.82  ? 371 LEU A O   1 
ATOM   2782  C  CB  . LEU A 1 371 ? 213.144 202.403 227.548 1.00 56.01  ? 371 LEU A CB  1 
ATOM   2783  C  CG  . LEU A 1 371 ? 212.443 201.120 227.982 1.00 62.39  ? 371 LEU A CG  1 
ATOM   2784  C  CD1 . LEU A 1 371 ? 211.756 201.305 229.320 1.00 69.05  ? 371 LEU A CD1 1 
ATOM   2785  C  CD2 . LEU A 1 371 ? 211.445 200.696 226.929 1.00 63.27  ? 371 LEU A CD2 1 
ATOM   2786  N  N   . GLU A 1 372 ? 215.027 204.364 225.885 1.00 58.34  ? 372 GLU A N   1 
ATOM   2787  C  CA  . GLU A 1 372 ? 215.200 205.395 224.867 1.00 60.17  ? 372 GLU A CA  1 
ATOM   2788  C  C   . GLU A 1 372 ? 216.124 204.922 223.756 1.00 58.21  ? 372 GLU A C   1 
ATOM   2789  O  O   . GLU A 1 372 ? 215.855 205.156 222.574 1.00 61.66  ? 372 GLU A O   1 
ATOM   2790  C  CB  . GLU A 1 372 ? 215.738 206.677 225.494 1.00 63.06  ? 372 GLU A CB  1 
ATOM   2791  C  CG  . GLU A 1 372 ? 214.939 207.910 225.129 1.00 70.33  ? 372 GLU A CG  1 
ATOM   2792  C  CD  . GLU A 1 372 ? 213.473 207.775 225.480 1.00 80.69  ? 372 GLU A CD  1 
ATOM   2793  O  OE1 . GLU A 1 372 ? 213.160 207.600 226.677 1.00 82.20  ? 372 GLU A OE1 1 
ATOM   2794  O  OE2 . GLU A 1 372 ? 212.633 207.842 224.559 1.00 81.34  ? 372 GLU A OE2 1 
ATOM   2795  N  N   . GLN A 1 373 ? 217.214 204.245 224.116 1.00 55.28  ? 373 GLN A N   1 
ATOM   2796  C  CA  . GLN A 1 373 ? 218.127 203.733 223.100 1.00 58.31  ? 373 GLN A CA  1 
ATOM   2797  C  C   . GLN A 1 373 ? 217.455 202.681 222.222 1.00 60.81  ? 373 GLN A C   1 
ATOM   2798  O  O   . GLN A 1 373 ? 217.645 202.666 220.999 1.00 59.67  ? 373 GLN A O   1 
ATOM   2799  C  CB  . GLN A 1 373 ? 219.377 203.158 223.756 1.00 57.55  ? 373 GLN A CB  1 
ATOM   2800  C  CG  . GLN A 1 373 ? 220.285 202.447 222.781 1.00 61.12  ? 373 GLN A CG  1 
ATOM   2801  C  CD  . GLN A 1 373 ? 221.724 202.443 223.223 1.00 68.01  ? 373 GLN A CD  1 
ATOM   2802  O  OE1 . GLN A 1 373 ? 222.030 202.737 224.375 1.00 71.49  ? 373 GLN A OE1 1 
ATOM   2803  N  NE2 . GLN A 1 373 ? 222.622 202.117 222.305 1.00 72.61  ? 373 GLN A NE2 1 
ATOM   2804  N  N   . GLU A 1 374 ? 216.668 201.790 222.826 1.00 61.06  ? 374 GLU A N   1 
ATOM   2805  C  CA  . GLU A 1 374 ? 215.961 200.785 222.042 1.00 57.82  ? 374 GLU A CA  1 
ATOM   2806  C  C   . GLU A 1 374 ? 214.962 201.424 221.086 1.00 59.91  ? 374 GLU A C   1 
ATOM   2807  O  O   . GLU A 1 374 ? 214.851 201.009 219.927 1.00 64.31  ? 374 GLU A O   1 
ATOM   2808  C  CB  . GLU A 1 374 ? 215.260 199.802 222.974 1.00 62.62  ? 374 GLU A CB  1 
ATOM   2809  C  CG  . GLU A 1 374 ? 214.432 198.752 222.272 1.00 70.72  ? 374 GLU A CG  1 
ATOM   2810  C  CD  . GLU A 1 374 ? 212.971 199.129 222.200 1.00 77.16  ? 374 GLU A CD  1 
ATOM   2811  O  OE1 . GLU A 1 374 ? 212.529 199.947 223.033 1.00 74.83  ? 374 GLU A OE1 1 
ATOM   2812  O  OE2 . GLU A 1 374 ? 212.263 198.609 221.313 1.00 82.00  ? 374 GLU A OE2 1 
ATOM   2813  N  N   . LYS A 1 375 ? 214.220 202.433 221.551 1.00 58.70  ? 375 LYS A N   1 
ATOM   2814  C  CA  . LYS A 1 375 ? 213.295 203.132 220.664 1.00 56.77  ? 375 LYS A CA  1 
ATOM   2815  C  C   . LYS A 1 375 ? 214.037 203.816 219.525 1.00 57.55  ? 375 LYS A C   1 
ATOM   2816  O  O   . LYS A 1 375 ? 213.576 203.812 218.375 1.00 60.93  ? 375 LYS A O   1 
ATOM   2817  C  CB  . LYS A 1 375 ? 212.485 204.157 221.445 1.00 57.39  ? 375 LYS A CB  1 
ATOM   2818  C  CG  . LYS A 1 375 ? 211.026 203.819 221.564 1.00 60.98  ? 375 LYS A CG  1 
ATOM   2819  C  CD  . LYS A 1 375 ? 210.256 204.969 222.193 1.00 72.97  ? 375 LYS A CD  1 
ATOM   2820  C  CE  . LYS A 1 375 ? 210.507 206.273 221.453 1.00 74.97  ? 375 LYS A CE  1 
ATOM   2821  N  NZ  . LYS A 1 375 ? 209.878 206.276 220.104 1.00 67.93  ? 375 LYS A NZ  1 
ATOM   2822  N  N   . SER A 1 376 ? 215.190 204.413 219.825 1.00 58.27  ? 376 SER A N   1 
ATOM   2823  C  CA  . SER A 1 376 ? 215.976 205.056 218.782 1.00 60.62  ? 376 SER A CA  1 
ATOM   2824  C  C   . SER A 1 376 ? 216.446 204.048 217.746 1.00 61.59  ? 376 SER A C   1 
ATOM   2825  O  O   . SER A 1 376 ? 216.454 204.342 216.546 1.00 66.48  ? 376 SER A O   1 
ATOM   2826  C  CB  . SER A 1 376 ? 217.168 205.788 219.397 1.00 63.68  ? 376 SER A CB  1 
ATOM   2827  O  OG  . SER A 1 376 ? 216.743 206.752 220.344 1.00 65.65  ? 376 SER A OG  1 
ATOM   2828  N  N   . ARG A 1 377 ? 216.861 202.861 218.187 1.00 58.74  ? 377 ARG A N   1 
ATOM   2829  C  CA  . ARG A 1 377 ? 217.298 201.851 217.227 1.00 57.01  ? 377 ARG A CA  1 
ATOM   2830  C  C   . ARG A 1 377 ? 216.125 201.348 216.394 1.00 59.54  ? 377 ARG A C   1 
ATOM   2831  O  O   . ARG A 1 377 ? 216.274 201.073 215.199 1.00 61.60  ? 377 ARG A O   1 
ATOM   2832  C  CB  . ARG A 1 377 ? 218.033 200.722 217.957 1.00 57.35  ? 377 ARG A CB  1 
ATOM   2833  C  CG  . ARG A 1 377 ? 218.649 199.623 217.094 1.00 55.77  ? 377 ARG A CG  1 
ATOM   2834  C  CD  . ARG A 1 377 ? 217.655 198.606 216.561 1.00 65.92  ? 377 ARG A CD  1 
ATOM   2835  N  NE  . ARG A 1 377 ? 216.426 198.600 217.342 1.00 72.56  ? 377 ARG A NE  1 
ATOM   2836  C  CZ  . ARG A 1 377 ? 216.153 197.716 218.291 1.00 76.98  ? 377 ARG A CZ  1 
ATOM   2837  N  NH1 . ARG A 1 377 ? 216.995 196.741 218.589 1.00 77.33  ? 377 ARG A NH1 1 
ATOM   2838  N  NH2 . ARG A 1 377 ? 215.009 197.816 218.961 1.00 76.18  ? 377 ARG A NH2 1 
ATOM   2839  N  N   . GLN A 1 378 ? 214.947 201.229 217.004 1.00 60.93  ? 378 GLN A N   1 
ATOM   2840  C  CA  . GLN A 1 378 ? 213.754 200.887 216.236 1.00 59.30  ? 378 GLN A CA  1 
ATOM   2841  C  C   . GLN A 1 378 ? 213.477 201.923 215.157 1.00 59.55  ? 378 GLN A C   1 
ATOM   2842  O  O   . GLN A 1 378 ? 213.113 201.574 214.028 1.00 62.90  ? 378 GLN A O   1 
ATOM   2843  C  CB  . GLN A 1 378 ? 212.549 200.759 217.166 1.00 59.89  ? 378 GLN A CB  1 
ATOM   2844  C  CG  . GLN A 1 378 ? 211.607 199.599 216.881 1.00 65.31  ? 378 GLN A CG  1 
ATOM   2845  C  CD  . GLN A 1 378 ? 212.203 198.230 217.133 1.00 72.52  ? 378 GLN A CD  1 
ATOM   2846  O  OE1 . GLN A 1 378 ? 213.417 198.045 217.120 1.00 75.58  ? 378 GLN A OE1 1 
ATOM   2847  N  NE2 . GLN A 1 378 ? 211.337 197.254 217.367 1.00 76.93  ? 378 GLN A NE2 1 
ATOM   2848  N  N   . HIS A 1 379 ? 213.629 203.203 215.486 1.00 60.77  ? 379 HIS A N   1 
ATOM   2849  C  CA  . HIS A 1 379 ? 213.358 204.242 214.498 1.00 63.64  ? 379 HIS A CA  1 
ATOM   2850  C  C   . HIS A 1 379 ? 214.431 204.291 213.415 1.00 63.65  ? 379 HIS A C   1 
ATOM   2851  O  O   . HIS A 1 379 ? 214.127 204.570 212.253 1.00 66.80  ? 379 HIS A O   1 
ATOM   2852  C  CB  . HIS A 1 379 ? 213.230 205.601 215.178 1.00 64.28  ? 379 HIS A CB  1 
ATOM   2853  C  CG  . HIS A 1 379 ? 212.689 206.671 214.285 1.00 65.41  ? 379 HIS A CG  1 
ATOM   2854  N  ND1 . HIS A 1 379 ? 211.383 207.105 214.354 1.00 67.52  ? 379 HIS A ND1 1 
ATOM   2855  C  CD2 . HIS A 1 379 ? 213.271 207.388 213.297 1.00 68.31  ? 379 HIS A CD2 1 
ATOM   2856  C  CE1 . HIS A 1 379 ? 211.187 208.049 213.452 1.00 71.49  ? 379 HIS A CE1 1 
ATOM   2857  N  NE2 . HIS A 1 379 ? 212.317 208.241 212.798 1.00 72.34  ? 379 HIS A NE2 1 
ATOM   2858  N  N   . ILE A 1 380 ? 215.694 204.058 213.777 1.00 62.60  ? 380 ILE A N   1 
ATOM   2859  C  CA  . ILE A 1 380 ? 216.760 204.117 212.782 1.00 63.64  ? 380 ILE A CA  1 
ATOM   2860  C  C   . ILE A 1 380 ? 216.684 202.924 211.838 1.00 70.51  ? 380 ILE A C   1 
ATOM   2861  O  O   . ILE A 1 380 ? 216.889 203.063 210.628 1.00 76.00  ? 380 ILE A O   1 
ATOM   2862  C  CB  . ILE A 1 380 ? 218.143 204.226 213.452 1.00 61.11  ? 380 ILE A CB  1 
ATOM   2863  C  CG1 . ILE A 1 380 ? 219.238 204.396 212.408 1.00 61.22  ? 380 ILE A CG1 1 
ATOM   2864  C  CG2 . ILE A 1 380 ? 218.481 202.999 214.233 1.00 66.35  ? 380 ILE A CG2 1 
ATOM   2865  C  CD1 . ILE A 1 380 ? 220.630 204.348 212.991 1.00 57.72  ? 380 ILE A CD1 1 
ATOM   2866  N  N   . GLU A 1 381 ? 216.381 201.735 212.367 1.00 69.89  ? 381 GLU A N   1 
ATOM   2867  C  CA  . GLU A 1 381 ? 216.389 200.540 211.532 1.00 70.49  ? 381 GLU A CA  1 
ATOM   2868  C  C   . GLU A 1 381 ? 215.196 200.510 210.594 1.00 68.86  ? 381 GLU A C   1 
ATOM   2869  O  O   . GLU A 1 381 ? 215.217 199.800 209.584 1.00 71.32  ? 381 GLU A O   1 
ATOM   2870  C  CB  . GLU A 1 381 ? 216.406 199.290 212.409 1.00 77.08  ? 381 GLU A CB  1 
ATOM   2871  C  CG  . GLU A 1 381 ? 217.782 198.917 212.933 1.00 84.22  ? 381 GLU A CG  1 
ATOM   2872  C  CD  . GLU A 1 381 ? 218.631 198.196 211.907 1.00 88.62  ? 381 GLU A CD  1 
ATOM   2873  O  OE1 . GLU A 1 381 ? 218.129 197.924 210.797 1.00 89.43  ? 381 GLU A OE1 1 
ATOM   2874  O  OE2 . GLU A 1 381 ? 219.803 197.894 212.215 1.00 92.39  ? 381 GLU A OE2 1 
ATOM   2875  N  N   . GLN A 1 382 ? 214.151 201.269 210.910 1.00 68.81  ? 382 GLN A N   1 
ATOM   2876  C  CA  . GLN A 1 382 ? 213.005 201.353 210.018 1.00 71.32  ? 382 GLN A CA  1 
ATOM   2877  C  C   . GLN A 1 382 ? 213.390 201.966 208.682 1.00 73.86  ? 382 GLN A C   1 
ATOM   2878  O  O   . GLN A 1 382 ? 212.736 201.703 207.666 1.00 82.76  ? 382 GLN A O   1 
ATOM   2879  C  CB  . GLN A 1 382 ? 211.896 202.170 210.679 1.00 69.17  ? 382 GLN A CB  1 
ATOM   2880  C  CG  . GLN A 1 382 ? 210.619 202.263 209.879 1.00 72.76  ? 382 GLN A CG  1 
ATOM   2881  C  CD  . GLN A 1 382 ? 210.525 203.562 209.112 1.00 79.85  ? 382 GLN A CD  1 
ATOM   2882  O  OE1 . GLN A 1 382 ? 211.285 204.498 209.360 1.00 79.19  ? 382 GLN A OE1 1 
ATOM   2883  N  NE2 . GLN A 1 382 ? 209.591 203.629 208.170 1.00 82.21  ? 382 GLN A NE2 1 
ATOM   2884  N  N   . LEU A 1 383 ? 214.458 202.762 208.653 1.00 67.60  ? 383 LEU A N   1 
ATOM   2885  C  CA  . LEU A 1 383 ? 214.869 203.446 207.438 1.00 66.10  ? 383 LEU A CA  1 
ATOM   2886  C  C   . LEU A 1 383 ? 216.335 203.240 207.079 1.00 69.97  ? 383 LEU A C   1 
ATOM   2887  O  O   . LEU A 1 383 ? 216.790 203.799 206.077 1.00 72.75  ? 383 LEU A O   1 
ATOM   2888  C  CB  . LEU A 1 383 ? 214.562 204.945 207.556 1.00 62.71  ? 383 LEU A CB  1 
ATOM   2889  C  CG  . LEU A 1 383 ? 215.315 205.796 208.578 1.00 63.71  ? 383 LEU A CG  1 
ATOM   2890  C  CD1 . LEU A 1 383 ? 216.498 206.497 207.951 1.00 68.31  ? 383 LEU A CD1 1 
ATOM   2891  C  CD2 . LEU A 1 383 ? 214.378 206.801 209.227 1.00 65.85  ? 383 LEU A CD2 1 
ATOM   2892  N  N   . ILE A 1 384 ? 217.086 202.466 207.856 1.00 72.08  ? 384 ILE A N   1 
ATOM   2893  C  CA  . ILE A 1 384 ? 218.493 202.207 207.564 1.00 74.50  ? 384 ILE A CA  1 
ATOM   2894  C  C   . ILE A 1 384 ? 218.636 201.068 206.559 1.00 73.53  ? 384 ILE A C   1 
ATOM   2895  O  O   . ILE A 1 384 ? 217.649 200.442 206.160 1.00 76.47  ? 384 ILE A O   1 
ATOM   2896  C  CB  . ILE A 1 384 ? 219.296 201.940 208.857 1.00 77.95  ? 384 ILE A CB  1 
ATOM   2897  C  CG1 . ILE A 1 384 ? 220.754 202.398 208.720 1.00 78.05  ? 384 ILE A CG1 1 
ATOM   2898  C  CG2 . ILE A 1 384 ? 219.246 200.488 209.278 1.00 75.92  ? 384 ILE A CG2 1 
ATOM   2899  C  CD1 . ILE A 1 384 ? 220.927 203.859 208.468 1.00 68.58  ? 384 ILE A CD1 1 
ATOM   2900  N  N   . GLN A 1 385 ? 219.864 200.865 206.087 1.00 74.37  ? 385 GLN A N   1 
ATOM   2901  C  CA  . GLN A 1 385 ? 220.321 199.788 205.209 1.00 79.15  ? 385 GLN A CA  1 
ATOM   2902  C  C   . GLN A 1 385 ? 219.550 199.752 203.883 1.00 76.85  ? 385 GLN A C   1 
ATOM   2903  O  O   . GLN A 1 385 ? 218.661 198.922 203.670 1.00 77.55  ? 385 GLN A O   1 
ATOM   2904  C  CB  . GLN A 1 385 ? 220.336 198.416 205.943 1.00 83.38  ? 385 GLN A CB  1 
ATOM   2905  C  CG  . GLN A 1 385 ? 219.123 197.433 205.952 1.00 86.30  ? 385 GLN A CG  1 
ATOM   2906  C  CD  . GLN A 1 385 ? 218.267 197.402 207.207 1.00 90.94  ? 385 GLN A CD  1 
ATOM   2907  O  OE1 . GLN A 1 385 ? 217.852 198.422 207.733 1.00 88.80  ? 385 GLN A OE1 1 
ATOM   2908  N  NE2 . GLN A 1 385 ? 218.005 196.196 207.694 1.00 93.18  ? 385 GLN A NE2 1 
ATOM   2909  N  N   . PHE A 1 386 ? 219.860 200.690 202.984 1.00 72.95  ? 386 PHE A N   1 
ATOM   2910  C  CA  . PHE A 1 386 ? 219.338 200.605 201.623 1.00 64.63  ? 386 PHE A CA  1 
ATOM   2911  C  C   . PHE A 1 386 ? 220.460 200.196 200.678 1.00 59.59  ? 386 PHE A C   1 
ATOM   2912  O  O   . PHE A 1 386 ? 220.819 200.947 199.770 1.00 52.27  ? 386 PHE A O   1 
ATOM   2913  C  CB  . PHE A 1 386 ? 218.708 201.924 201.182 1.00 57.58  ? 386 PHE A CB  1 
ATOM   2914  C  CG  . PHE A 1 386 ? 217.355 202.180 201.788 1.00 60.16  ? 386 PHE A CG  1 
ATOM   2915  C  CD1 . PHE A 1 386 ? 216.911 201.433 202.862 1.00 61.04  ? 386 PHE A CD1 1 
ATOM   2916  C  CD2 . PHE A 1 386 ? 216.538 203.181 201.304 1.00 60.83  ? 386 PHE A CD2 1 
ATOM   2917  C  CE1 . PHE A 1 386 ? 215.683 201.674 203.437 1.00 60.17  ? 386 PHE A CE1 1 
ATOM   2918  C  CE2 . PHE A 1 386 ? 215.297 203.422 201.878 1.00 59.93  ? 386 PHE A CE2 1 
ATOM   2919  C  CZ  . PHE A 1 386 ? 214.874 202.665 202.944 1.00 59.13  ? 386 PHE A CZ  1 
ATOM   2920  N  N   . ASP A 1 387 ? 221.027 199.014 200.911 1.00 61.00  ? 387 ASP A N   1 
ATOM   2921  C  CA  . ASP A 1 387 ? 222.023 198.378 200.058 1.00 59.61  ? 387 ASP A CA  1 
ATOM   2922  C  C   . ASP A 1 387 ? 223.256 199.253 199.893 1.00 57.38  ? 387 ASP A C   1 
ATOM   2923  O  O   . ASP A 1 387 ? 223.415 199.919 198.866 1.00 61.66  ? 387 ASP A O   1 
ATOM   2924  C  CB  . ASP A 1 387 ? 221.440 198.021 198.696 1.00 62.68  ? 387 ASP A CB  1 
ATOM   2925  C  CG  . ASP A 1 387 ? 222.431 197.292 197.820 1.00 65.34  ? 387 ASP A CG  1 
ATOM   2926  O  OD1 . ASP A 1 387 ? 223.318 196.610 198.372 1.00 72.10  ? 387 ASP A OD1 1 
ATOM   2927  O  OD2 . ASP A 1 387 ? 222.328 197.405 196.581 1.00 63.25  ? 387 ASP A OD2 1 
ATOM   2928  N  N   . PRO A 1 388 ? 224.120 199.304 200.886 1.00 55.32  ? 388 PRO A N   1 
ATOM   2929  C  CA  . PRO A 1 388 ? 225.298 200.170 200.801 1.00 58.04  ? 388 PRO A CA  1 
ATOM   2930  C  C   . PRO A 1 388 ? 226.313 199.760 199.744 1.00 59.26  ? 388 PRO A C   1 
ATOM   2931  O  O   . PRO A 1 388 ? 227.223 200.536 199.441 1.00 63.71  ? 388 PRO A O   1 
ATOM   2932  C  CB  . PRO A 1 388 ? 225.902 200.054 202.201 1.00 57.13  ? 388 PRO A CB  1 
ATOM   2933  C  CG  . PRO A 1 388 ? 225.516 198.689 202.648 1.00 56.88  ? 388 PRO A CG  1 
ATOM   2934  C  CD  . PRO A 1 388 ? 224.183 198.390 202.036 1.00 56.70  ? 388 PRO A CD  1 
ATOM   2935  N  N   . MET A 1 389 ? 226.186 198.565 199.173 1.00 57.92  ? 389 MET A N   1 
ATOM   2936  C  CA  . MET A 1 389 ? 227.201 198.069 198.249 1.00 63.60  ? 389 MET A CA  1 
ATOM   2937  C  C   . MET A 1 389 ? 226.933 198.451 196.795 1.00 65.21  ? 389 MET A C   1 
ATOM   2938  O  O   . MET A 1 389 ? 227.825 198.962 196.114 1.00 68.00  ? 389 MET A O   1 
ATOM   2939  C  CB  . MET A 1 389 ? 227.315 196.551 198.370 1.00 72.45  ? 389 MET A CB  1 
ATOM   2940  C  CG  . MET A 1 389 ? 227.846 195.892 197.121 1.00 80.06  ? 389 MET A CG  1 
ATOM   2941  S  SD  . MET A 1 389 ? 228.926 194.491 197.437 1.00 101.49 ? 389 MET A SD  1 
ATOM   2942  C  CE  . MET A 1 389 ? 229.197 193.945 195.758 1.00 94.86  ? 389 MET A CE  1 
ATOM   2943  N  N   . THR A 1 390 ? 225.726 198.192 196.299 1.00 61.95  ? 390 THR A N   1 
ATOM   2944  C  CA  . THR A 1 390 ? 225.380 198.481 194.916 1.00 61.24  ? 390 THR A CA  1 
ATOM   2945  C  C   . THR A 1 390 ? 224.442 199.669 194.778 1.00 56.44  ? 390 THR A C   1 
ATOM   2946  O  O   . THR A 1 390 ? 224.343 200.240 193.689 1.00 59.17  ? 390 THR A O   1 
ATOM   2947  C  CB  . THR A 1 390 ? 224.746 197.251 194.264 1.00 67.52  ? 390 THR A CB  1 
ATOM   2948  O  OG1 . THR A 1 390 ? 225.390 196.071 194.755 1.00 71.92  ? 390 THR A OG1 1 
ATOM   2949  C  CG2 . THR A 1 390 ? 224.907 197.303 192.755 1.00 71.86  ? 390 THR A CG2 1 
ATOM   2950  N  N   . GLY A 1 391 ? 223.758 200.053 195.842 1.00 50.92  ? 391 GLY A N   1 
ATOM   2951  C  CA  . GLY A 1 391 ? 222.994 201.272 195.848 1.00 48.69  ? 391 GLY A CA  1 
ATOM   2952  C  C   . GLY A 1 391 ? 221.544 201.121 195.480 1.00 49.27  ? 391 GLY A C   1 
ATOM   2953  O  O   . GLY A 1 391 ? 220.782 202.079 195.640 1.00 50.38  ? 391 GLY A O   1 
ATOM   2954  N  N   . LEU A 1 392 ? 221.134 199.954 195.004 1.00 53.85  ? 392 LEU A N   1 
ATOM   2955  C  CA  . LEU A 1 392 ? 219.743 199.728 194.681 1.00 54.24  ? 392 LEU A CA  1 
ATOM   2956  C  C   . LEU A 1 392 ? 218.928 199.727 195.962 1.00 51.95  ? 392 LEU A C   1 
ATOM   2957  O  O   . LEU A 1 392 ? 219.477 199.567 197.048 1.00 55.75  ? 392 LEU A O   1 
ATOM   2958  C  CB  . LEU A 1 392 ? 219.576 198.395 193.964 1.00 51.21  ? 392 LEU A CB  1 
ATOM   2959  C  CG  . LEU A 1 392 ? 220.432 198.132 192.735 1.00 50.32  ? 392 LEU A CG  1 
ATOM   2960  C  CD1 . LEU A 1 392 ? 220.638 196.650 192.589 1.00 50.20  ? 392 LEU A CD1 1 
ATOM   2961  C  CD2 . LEU A 1 392 ? 219.757 198.686 191.511 1.00 49.59  ? 392 LEU A CD2 1 
ATOM   2962  N  N   . PRO A 1 393 ? 217.624 199.926 195.876 1.00 49.51  ? 393 PRO A N   1 
ATOM   2963  C  CA  . PRO A 1 393 ? 216.804 199.819 197.084 1.00 54.67  ? 393 PRO A CA  1 
ATOM   2964  C  C   . PRO A 1 393 ? 216.862 198.421 197.675 1.00 58.49  ? 393 PRO A C   1 
ATOM   2965  O  O   . PRO A 1 393 ? 217.142 197.442 196.985 1.00 62.81  ? 393 PRO A O   1 
ATOM   2966  C  CB  . PRO A 1 393 ? 215.403 200.176 196.590 1.00 58.11  ? 393 PRO A CB  1 
ATOM   2967  C  CG  . PRO A 1 393 ? 215.663 201.106 195.466 1.00 58.01  ? 393 PRO A CG  1 
ATOM   2968  C  CD  . PRO A 1 393 ? 216.896 200.589 194.785 1.00 53.11  ? 393 PRO A CD  1 
ATOM   2969  N  N   . ASN A 1 394 ? 216.621 198.346 198.979 1.00 59.09  ? 394 ASN A N   1 
ATOM   2970  C  CA  . ASN A 1 394 ? 216.766 197.116 199.743 1.00 61.21  ? 394 ASN A CA  1 
ATOM   2971  C  C   . ASN A 1 394 ? 215.358 196.662 200.152 1.00 66.23  ? 394 ASN A C   1 
ATOM   2972  O  O   . ASN A 1 394 ? 214.366 197.338 199.868 1.00 67.87  ? 394 ASN A O   1 
ATOM   2973  C  CB  . ASN A 1 394 ? 217.766 197.388 200.875 1.00 67.68  ? 394 ASN A CB  1 
ATOM   2974  C  CG  . ASN A 1 394 ? 217.740 196.366 202.008 1.00 77.94  ? 394 ASN A CG  1 
ATOM   2975  O  OD1 . ASN A 1 394 ? 216.928 195.449 202.053 1.00 77.82  ? 394 ASN A OD1 1 
ATOM   2976  N  ND2 . ASN A 1 394 ? 218.668 196.531 202.939 1.00 79.57  ? 394 ASN A ND2 1 
ATOM   2977  N  N   . ARG A 1 395 ? 215.262 195.516 200.837 1.00 66.18  ? 395 ARG A N   1 
ATOM   2978  C  CA  . ARG A 1 395 ? 213.992 194.809 200.992 1.00 70.06  ? 395 ARG A CA  1 
ATOM   2979  C  C   . ARG A 1 395 ? 212.905 195.687 201.598 1.00 76.10  ? 395 ARG A C   1 
ATOM   2980  O  O   . ARG A 1 395 ? 211.737 195.599 201.201 1.00 79.72  ? 395 ARG A O   1 
ATOM   2981  C  CB  . ARG A 1 395 ? 214.198 193.562 201.847 1.00 69.04  ? 395 ARG A CB  1 
ATOM   2982  C  CG  . ARG A 1 395 ? 213.024 192.597 201.842 1.00 69.72  ? 395 ARG A CG  1 
ATOM   2983  C  CD  . ARG A 1 395 ? 213.394 191.273 202.480 1.00 64.19  ? 395 ARG A CD  1 
ATOM   2984  N  NE  . ARG A 1 395 ? 212.479 190.207 202.095 1.00 64.98  ? 395 ARG A NE  1 
ATOM   2985  C  CZ  . ARG A 1 395 ? 212.827 189.147 201.380 1.00 70.26  ? 395 ARG A CZ  1 
ATOM   2986  N  NH1 . ARG A 1 395 ? 214.067 188.977 200.957 1.00 70.23  ? 395 ARG A NH1 1 
ATOM   2987  N  NH2 . ARG A 1 395 ? 211.907 188.234 201.084 1.00 70.28  ? 395 ARG A NH2 1 
ATOM   2988  N  N   . ASN A 1 396 ? 213.258 196.525 202.571 1.00 77.76  ? 396 ASN A N   1 
ATOM   2989  C  CA  . ASN A 1 396 ? 212.258 197.400 203.175 1.00 82.66  ? 396 ASN A CA  1 
ATOM   2990  C  C   . ASN A 1 396 ? 211.689 198.371 202.150 1.00 84.28  ? 396 ASN A C   1 
ATOM   2991  O  O   . ASN A 1 396 ? 210.483 198.653 202.148 1.00 89.73  ? 396 ASN A O   1 
ATOM   2992  C  CB  . ASN A 1 396 ? 212.868 198.157 204.355 1.00 87.75  ? 396 ASN A CB  1 
ATOM   2993  C  CG  . ASN A 1 396 ? 213.156 197.255 205.536 1.00 92.43  ? 396 ASN A CG  1 
ATOM   2994  O  OD1 . ASN A 1 396 ? 212.695 196.116 205.587 1.00 92.26  ? 396 ASN A OD1 1 
ATOM   2995  N  ND2 . ASN A 1 396 ? 213.927 197.759 206.491 1.00 86.45  ? 396 ASN A ND2 1 
ATOM   2996  N  N   . ASN A 1 397 ? 212.546 198.896 201.272 1.00 77.23  ? 397 ASN A N   1 
ATOM   2997  C  CA  . ASN A 1 397 ? 212.071 199.782 200.219 1.00 76.87  ? 397 ASN A CA  1 
ATOM   2998  C  C   . ASN A 1 397 ? 211.093 199.055 199.309 1.00 85.24  ? 397 ASN A C   1 
ATOM   2999  O  O   . ASN A 1 397 ? 210.061 199.612 198.913 1.00 88.98  ? 397 ASN A O   1 
ATOM   3000  C  CB  . ASN A 1 397 ? 213.261 200.318 199.425 1.00 67.58  ? 397 ASN A CB  1 
ATOM   3001  C  CG  . ASN A 1 397 ? 212.927 201.570 198.642 1.00 68.84  ? 397 ASN A CG  1 
ATOM   3002  O  OD1 . ASN A 1 397 ? 212.006 201.584 197.831 1.00 78.29  ? 397 ASN A OD1 1 
ATOM   3003  N  ND2 . ASN A 1 397 ? 213.683 202.632 198.880 1.00 63.52  ? 397 ASN A ND2 1 
ATOM   3004  N  N   . LEU A 1 398 ? 211.395 197.796 198.986 1.00 84.23  ? 398 LEU A N   1 
ATOM   3005  C  CA  . LEU A 1 398 ? 210.503 197.001 198.151 1.00 80.80  ? 398 LEU A CA  1 
ATOM   3006  C  C   . LEU A 1 398 ? 209.159 196.781 198.827 1.00 86.27  ? 398 LEU A C   1 
ATOM   3007  O  O   . LEU A 1 398 ? 208.111 196.879 198.181 1.00 89.03  ? 398 LEU A O   1 
ATOM   3008  C  CB  . LEU A 1 398 ? 211.154 195.661 197.833 1.00 72.90  ? 398 LEU A CB  1 
ATOM   3009  C  CG  . LEU A 1 398 ? 210.260 194.649 197.137 1.00 72.43  ? 398 LEU A CG  1 
ATOM   3010  C  CD1 . LEU A 1 398 ? 209.944 195.134 195.744 1.00 77.38  ? 398 LEU A CD1 1 
ATOM   3011  C  CD2 . LEU A 1 398 ? 210.933 193.303 197.100 1.00 71.40  ? 398 LEU A CD2 1 
ATOM   3012  N  N   . HIS A 1 399 ? 209.172 196.456 200.123 1.00 89.18  ? 399 HIS A N   1 
ATOM   3013  C  CA  . HIS A 1 399 ? 207.918 196.234 200.837 1.00 90.41  ? 399 HIS A CA  1 
ATOM   3014  C  C   . HIS A 1 399 ? 207.085 197.502 200.865 1.00 94.85  ? 399 HIS A C   1 
ATOM   3015  O  O   . HIS A 1 399 ? 205.868 197.460 200.645 1.00 100.19 ? 399 HIS A O   1 
ATOM   3016  C  CB  . HIS A 1 399 ? 208.190 195.737 202.257 1.00 86.98  ? 399 HIS A CB  1 
ATOM   3017  C  CG  . HIS A 1 399 ? 208.616 194.304 202.324 1.00 82.67  ? 399 HIS A CG  1 
ATOM   3018  N  ND1 . HIS A 1 399 ? 209.155 193.741 203.458 1.00 79.81  ? 399 HIS A ND1 1 
ATOM   3019  C  CD2 . HIS A 1 399 ? 208.586 193.321 201.395 1.00 79.22  ? 399 HIS A CD2 1 
ATOM   3020  C  CE1 . HIS A 1 399 ? 209.439 192.472 203.225 1.00 73.49  ? 399 HIS A CE1 1 
ATOM   3021  N  NE2 . HIS A 1 399 ? 209.103 192.192 201.981 1.00 72.70  ? 399 HIS A NE2 1 
ATOM   3022  N  N   . ASN A 1 400 ? 207.726 198.646 201.106 1.00 94.56  ? 400 ASN A N   1 
ATOM   3023  C  CA  . ASN A 1 400 ? 206.996 199.909 201.090 1.00 96.19  ? 400 ASN A CA  1 
ATOM   3024  C  C   . ASN A 1 400 ? 206.398 200.182 199.715 1.00 97.20  ? 400 ASN A C   1 
ATOM   3025  O  O   . ASN A 1 400 ? 205.239 200.602 199.606 1.00 103.69 ? 400 ASN A O   1 
ATOM   3026  C  CB  . ASN A 1 400 ? 207.915 201.054 201.512 1.00 97.78  ? 400 ASN A CB  1 
ATOM   3027  C  CG  . ASN A 1 400 ? 208.334 200.960 202.964 1.00 100.03 ? 400 ASN A CG  1 
ATOM   3028  O  OD1 . ASN A 1 400 ? 207.789 200.164 203.730 1.00 102.20 ? 400 ASN A OD1 1 
ATOM   3029  N  ND2 . ASN A 1 400 ? 209.307 201.776 203.353 1.00 95.83  ? 400 ASN A ND2 1 
ATOM   3030  N  N   . TYR A 1 401 ? 207.166 199.936 198.651 1.00 92.61  ? 401 TYR A N   1 
ATOM   3031  C  CA  . TYR A 1 401 ? 206.672 200.240 197.312 1.00 96.09  ? 401 TYR A CA  1 
ATOM   3032  C  C   . TYR A 1 401 ? 205.521 199.325 196.917 1.00 102.54 ? 401 TYR A C   1 
ATOM   3033  O  O   . TYR A 1 401 ? 204.532 199.781 196.332 1.00 105.67 ? 401 TYR A O   1 
ATOM   3034  C  CB  . TYR A 1 401 ? 207.805 200.143 196.296 1.00 90.08  ? 401 TYR A CB  1 
ATOM   3035  C  CG  . TYR A 1 401 ? 207.469 200.801 194.981 1.00 92.70  ? 401 TYR A CG  1 
ATOM   3036  C  CD1 . TYR A 1 401 ? 206.599 201.879 194.927 1.00 102.55 ? 401 TYR A CD1 1 
ATOM   3037  C  CD2 . TYR A 1 401 ? 208.028 200.353 193.797 1.00 88.20  ? 401 TYR A CD2 1 
ATOM   3038  C  CE1 . TYR A 1 401 ? 206.289 202.486 193.730 1.00 102.02 ? 401 TYR A CE1 1 
ATOM   3039  C  CE2 . TYR A 1 401 ? 207.726 200.954 192.595 1.00 88.37  ? 401 TYR A CE2 1 
ATOM   3040  C  CZ  . TYR A 1 401 ? 206.856 202.019 192.566 1.00 93.85  ? 401 TYR A CZ  1 
ATOM   3041  O  OH  . TYR A 1 401 ? 206.552 202.621 191.367 1.00 92.27  ? 401 TYR A OH  1 
ATOM   3042  N  N   . LEU A 1 402 ? 205.629 198.033 197.220 1.00 101.56 ? 402 LEU A N   1 
ATOM   3043  C  CA  . LEU A 1 402 ? 204.541 197.118 196.893 1.00 102.22 ? 402 LEU A CA  1 
ATOM   3044  C  C   . LEU A 1 402 ? 203.301 197.410 197.726 1.00 106.97 ? 402 LEU A C   1 
ATOM   3045  O  O   . LEU A 1 402 ? 202.175 197.298 197.227 1.00 110.37 ? 402 LEU A O   1 
ATOM   3046  C  CB  . LEU A 1 402 ? 204.994 195.669 197.059 1.00 98.61  ? 402 LEU A CB  1 
ATOM   3047  C  CG  . LEU A 1 402 ? 205.679 195.018 195.850 1.00 93.78  ? 402 LEU A CG  1 
ATOM   3048  C  CD1 . LEU A 1 402 ? 206.594 195.974 195.105 1.00 91.72  ? 402 LEU A CD1 1 
ATOM   3049  C  CD2 . LEU A 1 402 ? 206.442 193.774 196.269 1.00 87.31  ? 402 LEU A CD2 1 
ATOM   3050  N  N   . ASP A 1 403 ? 203.478 197.800 198.990 1.00 108.23 ? 403 ASP A N   1 
ATOM   3051  C  CA  . ASP A 1 403 ? 202.328 198.216 199.782 1.00 111.38 ? 403 ASP A CA  1 
ATOM   3052  C  C   . ASP A 1 403 ? 201.664 199.445 199.177 1.00 116.13 ? 403 ASP A C   1 
ATOM   3053  O  O   . ASP A 1 403 ? 200.431 199.537 199.136 1.00 120.02 ? 403 ASP A O   1 
ATOM   3054  C  CB  . ASP A 1 403 ? 202.754 198.488 201.223 1.00 111.15 ? 403 ASP A CB  1 
ATOM   3055  C  CG  . ASP A 1 403 ? 202.439 197.334 202.149 1.00 117.24 ? 403 ASP A CG  1 
ATOM   3056  O  OD1 . ASP A 1 403 ? 202.302 196.197 201.652 1.00 118.84 ? 403 ASP A OD1 1 
ATOM   3057  O  OD2 . ASP A 1 403 ? 202.327 197.562 203.372 1.00 119.28 ? 403 ASP A OD2 1 
ATOM   3058  N  N   . ASP A 1 404 ? 202.464 200.402 198.703 1.00 115.04 ? 404 ASP A N   1 
ATOM   3059  C  CA  . ASP A 1 404 ? 201.896 201.586 198.069 1.00 116.98 ? 404 ASP A CA  1 
ATOM   3060  C  C   . ASP A 1 404 ? 201.129 201.199 196.810 1.00 119.36 ? 404 ASP A C   1 
ATOM   3061  O  O   . ASP A 1 404 ? 200.030 201.707 196.558 1.00 120.70 ? 404 ASP A O   1 
ATOM   3062  C  CB  . ASP A 1 404 ? 203.011 202.588 197.754 1.00 116.56 ? 404 ASP A CB  1 
ATOM   3063  C  CG  . ASP A 1 404 ? 202.638 203.581 196.659 1.00 121.33 ? 404 ASP A CG  1 
ATOM   3064  O  OD1 . ASP A 1 404 ? 201.462 203.997 196.579 1.00 122.88 ? 404 ASP A OD1 1 
ATOM   3065  O  OD2 . ASP A 1 404 ? 203.533 203.948 195.869 1.00 123.88 ? 404 ASP A OD2 1 
ATOM   3066  N  N   . LEU A 1 405 ? 201.688 200.285 196.015 1.00 117.01 ? 405 LEU A N   1 
ATOM   3067  C  CA  . LEU A 1 405 ? 201.004 199.842 194.803 1.00 119.60 ? 405 LEU A CA  1 
ATOM   3068  C  C   . LEU A 1 405 ? 199.681 199.163 195.133 1.00 120.80 ? 405 LEU A C   1 
ATOM   3069  O  O   . LEU A 1 405 ? 198.672 199.391 194.456 1.00 121.06 ? 405 LEU A O   1 
ATOM   3070  C  CB  . LEU A 1 405 ? 201.906 198.901 194.003 1.00 118.00 ? 405 LEU A CB  1 
ATOM   3071  C  CG  . LEU A 1 405 ? 203.097 199.543 193.290 1.00 115.57 ? 405 LEU A CG  1 
ATOM   3072  C  CD1 . LEU A 1 405 ? 203.834 198.518 192.443 1.00 108.80 ? 405 LEU A CD1 1 
ATOM   3073  C  CD2 . LEU A 1 405 ? 202.641 200.718 192.439 1.00 110.57 ? 405 LEU A CD2 1 
ATOM   3074  N  N   . VAL A 1 406 ? 199.668 198.325 196.172 1.00 120.96 ? 406 VAL A N   1 
ATOM   3075  C  CA  . VAL A 1 406 ? 198.428 197.674 196.590 1.00 122.30 ? 406 VAL A CA  1 
ATOM   3076  C  C   . VAL A 1 406 ? 197.409 198.712 197.041 1.00 123.87 ? 406 VAL A C   1 
ATOM   3077  O  O   . VAL A 1 406 ? 196.222 198.628 196.702 1.00 121.96 ? 406 VAL A O   1 
ATOM   3078  C  CB  . VAL A 1 406 ? 198.713 196.639 197.696 1.00 119.83 ? 406 VAL A CB  1 
ATOM   3079  C  CG1 . VAL A 1 406 ? 197.420 196.205 198.370 1.00 116.46 ? 406 VAL A CG1 1 
ATOM   3080  C  CG2 . VAL A 1 406 ? 199.448 195.439 197.120 1.00 117.39 ? 406 VAL A CG2 1 
ATOM   3081  N  N   . ASP A 1 407 ? 197.856 199.710 197.808 1.00 125.99 ? 407 ASP A N   1 
ATOM   3082  C  CA  . ASP A 1 407 ? 196.960 200.787 198.216 1.00 127.06 ? 407 ASP A CA  1 
ATOM   3083  C  C   . ASP A 1 407 ? 196.445 201.570 197.016 1.00 126.75 ? 407 ASP A C   1 
ATOM   3084  O  O   . ASP A 1 407 ? 195.365 202.167 197.081 1.00 124.28 ? 407 ASP A O   1 
ATOM   3085  C  CB  . ASP A 1 407 ? 197.669 201.722 199.197 1.00 124.86 ? 407 ASP A CB  1 
ATOM   3086  C  CG  . ASP A 1 407 ? 197.838 201.105 200.571 1.00 128.22 ? 407 ASP A CG  1 
ATOM   3087  O  OD1 . ASP A 1 407 ? 197.249 200.032 200.819 1.00 129.59 ? 407 ASP A OD1 1 
ATOM   3088  O  OD2 . ASP A 1 407 ? 198.556 201.695 201.405 1.00 127.83 ? 407 ASP A OD2 1 
ATOM   3089  N  N   . LYS A 1 408 ? 197.198 201.580 195.918 1.00 127.08 ? 408 LYS A N   1 
ATOM   3090  C  CA  . LYS A 1 408 ? 196.749 202.211 194.684 1.00 126.72 ? 408 LYS A CA  1 
ATOM   3091  C  C   . LYS A 1 408 ? 195.847 201.307 193.854 1.00 126.28 ? 408 LYS A C   1 
ATOM   3092  O  O   . LYS A 1 408 ? 195.401 201.728 192.780 1.00 125.91 ? 408 LYS A O   1 
ATOM   3093  C  CB  . LYS A 1 408 ? 197.952 202.651 193.846 1.00 123.93 ? 408 LYS A CB  1 
ATOM   3094  C  CG  . LYS A 1 408 ? 198.575 203.962 194.297 1.00 120.75 ? 408 LYS A CG  1 
ATOM   3095  C  CD  . LYS A 1 408 ? 199.859 204.255 193.538 1.00 118.25 ? 408 LYS A CD  1 
ATOM   3096  C  CE  . LYS A 1 408 ? 200.429 205.612 193.921 1.00 117.39 ? 408 LYS A CE  1 
ATOM   3097  N  NZ  . LYS A 1 408 ? 201.794 205.819 193.365 1.00 115.90 ? 408 LYS A NZ  1 
ATOM   3098  N  N   . ALA A 1 409 ? 195.575 200.087 194.324 1.00 126.15 ? 409 ALA A N   1 
ATOM   3099  C  CA  . ALA A 1 409 ? 194.696 199.138 193.636 1.00 124.75 ? 409 ALA A CA  1 
ATOM   3100  C  C   . ALA A 1 409 ? 195.184 198.843 192.220 1.00 122.37 ? 409 ALA A C   1 
ATOM   3101  O  O   . ALA A 1 409 ? 194.394 198.724 191.282 1.00 120.14 ? 409 ALA A O   1 
ATOM   3102  C  CB  . ALA A 1 409 ? 193.248 199.634 193.620 1.00 124.86 ? 409 ALA A CB  1 
ATOM   3103  N  N   . VAL A 1 410 ? 196.499 198.725 192.064 1.00 120.37 ? 410 VAL A N   1 
ATOM   3104  C  CA  . VAL A 1 410 ? 197.121 198.401 190.787 1.00 113.92 ? 410 VAL A CA  1 
ATOM   3105  C  C   . VAL A 1 410 ? 197.898 197.107 190.967 1.00 106.52 ? 410 VAL A C   1 
ATOM   3106  O  O   . VAL A 1 410 ? 198.750 197.007 191.857 1.00 105.82 ? 410 VAL A O   1 
ATOM   3107  C  CB  . VAL A 1 410 ? 198.038 199.528 190.293 1.00 114.32 ? 410 VAL A CB  1 
ATOM   3108  C  CG1 . VAL A 1 410 ? 198.743 199.114 189.012 1.00 108.86 ? 410 VAL A CG1 1 
ATOM   3109  C  CG2 . VAL A 1 410 ? 197.240 200.805 190.082 1.00 115.54 ? 410 VAL A CG2 1 
ATOM   3110  N  N   . SER A 1 411 ? 197.605 196.123 190.129 1.00 103.55 ? 411 SER A N   1 
ATOM   3111  C  CA  . SER A 1 411 ? 198.260 194.826 190.230 1.00 101.00 ? 411 SER A CA  1 
ATOM   3112  C  C   . SER A 1 411 ? 199.649 194.892 189.611 1.00 92.88  ? 411 SER A C   1 
ATOM   3113  O  O   . SER A 1 411 ? 199.777 195.279 188.445 1.00 93.24  ? 411 SER A O   1 
ATOM   3114  C  CB  . SER A 1 411 ? 197.428 193.754 189.541 1.00 102.36 ? 411 SER A CB  1 
ATOM   3115  O  OG  . SER A 1 411 ? 196.173 193.598 190.181 1.00 107.25 ? 411 SER A OG  1 
ATOM   3116  N  N   . PRO A 1 412 ? 200.702 194.545 190.342 1.00 84.78  ? 412 PRO A N   1 
ATOM   3117  C  CA  . PRO A 1 412 ? 202.045 194.562 189.770 1.00 78.11  ? 412 PRO A CA  1 
ATOM   3118  C  C   . PRO A 1 412 ? 202.445 193.200 189.231 1.00 78.06  ? 412 PRO A C   1 
ATOM   3119  O  O   . PRO A 1 412 ? 201.837 192.173 189.531 1.00 85.63  ? 412 PRO A O   1 
ATOM   3120  C  CB  . PRO A 1 412 ? 202.917 194.941 190.971 1.00 81.57  ? 412 PRO A CB  1 
ATOM   3121  C  CG  . PRO A 1 412 ? 202.180 194.360 192.147 1.00 89.59  ? 412 PRO A CG  1 
ATOM   3122  C  CD  . PRO A 1 412 ? 200.724 194.204 191.772 1.00 87.84  ? 412 PRO A CD  1 
ATOM   3123  N  N   . VAL A 1 413 ? 203.490 193.214 188.419 1.00 72.31  ? 413 VAL A N   1 
ATOM   3124  C  CA  . VAL A 1 413 ? 204.167 192.003 187.986 1.00 71.10  ? 413 VAL A CA  1 
ATOM   3125  C  C   . VAL A 1 413 ? 205.528 192.013 188.651 1.00 65.72  ? 413 VAL A C   1 
ATOM   3126  O  O   . VAL A 1 413 ? 206.313 192.955 188.461 1.00 68.24  ? 413 VAL A O   1 
ATOM   3127  C  CB  . VAL A 1 413 ? 204.293 191.931 186.460 1.00 71.58  ? 413 VAL A CB  1 
ATOM   3128  C  CG1 . VAL A 1 413 ? 205.242 190.819 186.068 1.00 65.71  ? 413 VAL A CG1 1 
ATOM   3129  C  CG2 . VAL A 1 413 ? 202.932 191.721 185.831 1.00 77.42  ? 413 VAL A CG2 1 
ATOM   3130  N  N   . VAL A 1 414 ? 205.807 190.982 189.437 1.00 57.17  ? 414 VAL A N   1 
ATOM   3131  C  CA  . VAL A 1 414 ? 207.017 190.924 190.240 1.00 49.89  ? 414 VAL A CA  1 
ATOM   3132  C  C   . VAL A 1 414 ? 207.883 189.792 189.720 1.00 50.78  ? 414 VAL A C   1 
ATOM   3133  O  O   . VAL A 1 414 ? 207.462 188.628 189.719 1.00 62.05  ? 414 VAL A O   1 
ATOM   3134  C  CB  . VAL A 1 414 ? 206.697 190.742 191.728 1.00 54.98  ? 414 VAL A CB  1 
ATOM   3135  C  CG1 . VAL A 1 414 ? 206.339 192.072 192.341 1.00 66.14  ? 414 VAL A CG1 1 
ATOM   3136  C  CG2 . VAL A 1 414 ? 205.555 189.773 191.906 1.00 65.22  ? 414 VAL A CG2 1 
ATOM   3137  N  N   . TYR A 1 415 ? 209.082 190.133 189.268 1.00 44.58  ? 415 TYR A N   1 
ATOM   3138  C  CA  . TYR A 1 415 ? 210.101 189.159 188.920 1.00 44.96  ? 415 TYR A CA  1 
ATOM   3139  C  C   . TYR A 1 415 ? 211.004 188.977 190.123 1.00 46.84  ? 415 TYR A C   1 
ATOM   3140  O  O   . TYR A 1 415 ? 211.495 189.960 190.685 1.00 50.94  ? 415 TYR A O   1 
ATOM   3141  C  CB  . TYR A 1 415 ? 210.955 189.612 187.732 1.00 48.88  ? 415 TYR A CB  1 
ATOM   3142  C  CG  . TYR A 1 415 ? 210.238 189.907 186.434 1.00 49.48  ? 415 TYR A CG  1 
ATOM   3143  C  CD1 . TYR A 1 415 ? 209.377 190.985 186.313 1.00 48.63  ? 415 TYR A CD1 1 
ATOM   3144  C  CD2 . TYR A 1 415 ? 210.458 189.127 185.316 1.00 47.27  ? 415 TYR A CD2 1 
ATOM   3145  C  CE1 . TYR A 1 415 ? 208.745 191.255 185.132 1.00 44.94  ? 415 TYR A CE1 1 
ATOM   3146  C  CE2 . TYR A 1 415 ? 209.824 189.393 184.135 1.00 47.67  ? 415 TYR A CE2 1 
ATOM   3147  C  CZ  . TYR A 1 415 ? 208.975 190.458 184.051 1.00 46.60  ? 415 TYR A CZ  1 
ATOM   3148  O  OH  . TYR A 1 415 ? 208.338 190.725 182.869 1.00 54.88  ? 415 TYR A OH  1 
ATOM   3149  N  N   . LEU A 1 416 ? 211.227 187.731 190.508 1.00 51.75  ? 416 LEU A N   1 
ATOM   3150  C  CA  . LEU A 1 416 ? 212.286 187.382 191.440 1.00 54.71  ? 416 LEU A CA  1 
ATOM   3151  C  C   . LEU A 1 416 ? 213.411 186.747 190.636 1.00 52.58  ? 416 LEU A C   1 
ATOM   3152  O  O   . LEU A 1 416 ? 213.190 185.761 189.925 1.00 60.40  ? 416 LEU A O   1 
ATOM   3153  C  CB  . LEU A 1 416 ? 211.783 186.432 192.523 1.00 61.84  ? 416 LEU A CB  1 
ATOM   3154  C  CG  . LEU A 1 416 ? 211.624 187.078 193.890 1.00 62.95  ? 416 LEU A CG  1 
ATOM   3155  C  CD1 . LEU A 1 416 ? 210.480 188.065 193.853 1.00 61.20  ? 416 LEU A CD1 1 
ATOM   3156  C  CD2 . LEU A 1 416 ? 211.395 186.026 194.955 1.00 69.45  ? 416 LEU A CD2 1 
ATOM   3157  N  N   . ILE A 1 417 ? 214.605 187.311 190.744 1.00 43.26  ? 417 ILE A N   1 
ATOM   3158  C  CA  . ILE A 1 417 ? 215.721 186.966 189.881 1.00 41.52  ? 417 ILE A CA  1 
ATOM   3159  C  C   . ILE A 1 417 ? 216.840 186.411 190.736 1.00 47.30  ? 417 ILE A C   1 
ATOM   3160  O  O   . ILE A 1 417 ? 217.223 187.029 191.732 1.00 57.87  ? 417 ILE A O   1 
ATOM   3161  C  CB  . ILE A 1 417 ? 216.206 188.190 189.092 1.00 42.98  ? 417 ILE A CB  1 
ATOM   3162  C  CG1 . ILE A 1 417 ? 215.070 188.780 188.263 1.00 45.13  ? 417 ILE A CG1 1 
ATOM   3163  C  CG2 . ILE A 1 417 ? 217.354 187.818 188.225 1.00 47.33  ? 417 ILE A CG2 1 
ATOM   3164  C  CD1 . ILE A 1 417 ? 215.321 190.186 187.810 1.00 46.28  ? 417 ILE A CD1 1 
ATOM   3165  N  N   . GLY A 1 418 ? 217.376 185.261 190.351 1.00 51.37  ? 418 GLY A N   1 
ATOM   3166  C  CA  . GLY A 1 418 ? 218.453 184.674 191.118 1.00 60.53  ? 418 GLY A CA  1 
ATOM   3167  C  C   . GLY A 1 418 ? 219.612 184.191 190.276 1.00 68.42  ? 418 GLY A C   1 
ATOM   3168  O  O   . GLY A 1 418 ? 219.413 183.562 189.233 1.00 74.95  ? 418 GLY A O   1 
ATOM   3169  N  N   . VAL A 1 419 ? 220.825 184.472 190.723 1.00 69.80  ? 419 VAL A N   1 
ATOM   3170  C  CA  . VAL A 1 419 ? 222.029 184.115 189.987 1.00 78.04  ? 419 VAL A CA  1 
ATOM   3171  C  C   . VAL A 1 419 ? 222.533 182.769 190.495 1.00 88.09  ? 419 VAL A C   1 
ATOM   3172  O  O   . VAL A 1 419 ? 222.638 182.553 191.708 1.00 87.52  ? 419 VAL A O   1 
ATOM   3173  C  CB  . VAL A 1 419 ? 223.096 185.207 190.135 1.00 74.28  ? 419 VAL A CB  1 
ATOM   3174  C  CG1 . VAL A 1 419 ? 224.198 185.001 189.126 1.00 82.73  ? 419 VAL A CG1 1 
ATOM   3175  C  CG2 . VAL A 1 419 ? 222.459 186.566 189.971 1.00 66.22  ? 419 VAL A CG2 1 
ATOM   3176  N  N   . ASP A 1 420 ? 222.840 181.859 189.569 1.00 93.15  ? 420 ASP A N   1 
ATOM   3177  C  CA  . ASP A 1 420 ? 223.080 180.459 189.916 1.00 96.00  ? 420 ASP A CA  1 
ATOM   3178  C  C   . ASP A 1 420 ? 224.557 180.151 190.146 1.00 103.25 ? 420 ASP A C   1 
ATOM   3179  O  O   . ASP A 1 420 ? 224.945 179.721 191.237 1.00 106.77 ? 420 ASP A O   1 
ATOM   3180  C  CB  . ASP A 1 420 ? 222.526 179.547 188.816 1.00 95.96  ? 420 ASP A CB  1 
ATOM   3181  C  CG  . ASP A 1 420 ? 221.177 180.005 188.301 1.00 92.27  ? 420 ASP A CG  1 
ATOM   3182  O  OD1 . ASP A 1 420 ? 220.408 180.599 189.086 1.00 90.13  ? 420 ASP A OD1 1 
ATOM   3183  O  OD2 . ASP A 1 420 ? 220.885 179.773 187.109 1.00 90.24  ? 420 ASP A OD2 1 
ATOM   3184  N  N   . HIS A 1 421 ? 225.389 180.368 189.127 1.00 108.17 ? 421 HIS A N   1 
ATOM   3185  C  CA  . HIS A 1 421 ? 226.786 179.953 189.179 1.00 122.09 ? 421 HIS A CA  1 
ATOM   3186  C  C   . HIS A 1 421 ? 227.612 180.784 190.151 1.00 123.78 ? 421 HIS A C   1 
ATOM   3187  O  O   . HIS A 1 421 ? 228.775 180.444 190.397 1.00 126.74 ? 421 HIS A O   1 
ATOM   3188  C  CB  . HIS A 1 421 ? 227.400 180.023 187.779 1.00 122.84 ? 421 HIS A CB  1 
ATOM   3189  C  CG  . HIS A 1 421 ? 228.671 179.246 187.636 1.00 131.41 ? 421 HIS A CG  1 
ATOM   3190  N  ND1 . HIS A 1 421 ? 228.839 177.989 188.175 1.00 134.18 ? 421 HIS A ND1 1 
ATOM   3191  C  CD2 . HIS A 1 421 ? 229.836 179.549 187.017 1.00 130.00 ? 421 HIS A CD2 1 
ATOM   3192  C  CE1 . HIS A 1 421 ? 230.053 177.550 187.892 1.00 134.79 ? 421 HIS A CE1 1 
ATOM   3193  N  NE2 . HIS A 1 421 ? 230.678 178.478 187.190 1.00 134.87 ? 421 HIS A NE2 1 
ATOM   3194  N  N   . ILE A 1 422 ? 227.039 181.853 190.708 1.00 118.42 ? 422 ILE A N   1 
ATOM   3195  C  CA  . ILE A 1 422 ? 227.780 182.734 191.604 1.00 118.86 ? 422 ILE A CA  1 
ATOM   3196  C  C   . ILE A 1 422 ? 228.222 182.002 192.865 1.00 121.27 ? 422 ILE A C   1 
ATOM   3197  O  O   . ILE A 1 422 ? 229.307 182.268 193.394 1.00 124.10 ? 422 ILE A O   1 
ATOM   3198  C  CB  . ILE A 1 422 ? 226.927 183.977 191.931 1.00 113.41 ? 422 ILE A CB  1 
ATOM   3199  C  CG1 . ILE A 1 422 ? 227.706 184.955 192.814 1.00 117.17 ? 422 ILE A CG1 1 
ATOM   3200  C  CG2 . ILE A 1 422 ? 225.607 183.572 192.567 1.00 106.28 ? 422 ILE A CG2 1 
ATOM   3201  C  CD1 . ILE A 1 422 ? 228.807 185.683 192.080 1.00 113.70 ? 422 ILE A CD1 1 
ATOM   3202  N  N   . GLN A 1 423 ? 227.403 181.075 193.368 1.00 121.08 ? 423 GLN A N   1 
ATOM   3203  C  CA  . GLN A 1 423 ? 227.764 180.357 194.586 1.00 123.24 ? 423 GLN A CA  1 
ATOM   3204  C  C   . GLN A 1 423 ? 228.999 179.490 194.373 1.00 127.66 ? 423 GLN A C   1 
ATOM   3205  O  O   . GLN A 1 423 ? 229.850 179.374 195.263 1.00 130.49 ? 423 GLN A O   1 
ATOM   3206  C  CB  . GLN A 1 423 ? 226.586 179.509 195.062 1.00 120.00 ? 423 GLN A CB  1 
ATOM   3207  C  CG  . GLN A 1 423 ? 225.640 180.239 196.002 1.00 118.72 ? 423 GLN A CG  1 
ATOM   3208  C  CD  . GLN A 1 423 ? 224.915 181.387 195.324 1.00 114.96 ? 423 GLN A CD  1 
ATOM   3209  O  OE1 . GLN A 1 423 ? 224.145 181.181 194.386 1.00 110.24 ? 423 GLN A OE1 1 
ATOM   3210  N  NE2 . GLN A 1 423 ? 225.156 182.604 195.798 1.00 111.60 ? 423 GLN A NE2 1 
ATOM   3211  N  N   . ASP A 1 424 ? 229.109 178.866 193.199 1.00 126.86 ? 424 ASP A N   1 
ATOM   3212  C  CA  . ASP A 1 424 ? 230.293 178.069 192.897 1.00 131.17 ? 424 ASP A CA  1 
ATOM   3213  C  C   . ASP A 1 424 ? 231.546 178.934 192.865 1.00 131.50 ? 424 ASP A C   1 
ATOM   3214  O  O   . ASP A 1 424 ? 232.596 178.537 193.381 1.00 132.87 ? 424 ASP A O   1 
ATOM   3215  C  CB  . ASP A 1 424 ? 230.110 177.340 191.566 1.00 133.84 ? 424 ASP A CB  1 
ATOM   3216  C  CG  . ASP A 1 424 ? 229.025 176.283 191.625 1.00 134.74 ? 424 ASP A CG  1 
ATOM   3217  O  OD1 . ASP A 1 424 ? 228.803 175.718 192.716 1.00 135.58 ? 424 ASP A OD1 1 
ATOM   3218  O  OD2 . ASP A 1 424 ? 228.395 176.017 190.580 1.00 133.88 ? 424 ASP A OD2 1 
ATOM   3219  N  N   . VAL A 1 425 ? 231.458 180.121 192.263 1.00 128.74 ? 425 VAL A N   1 
ATOM   3220  C  CA  . VAL A 1 425 ? 232.612 181.013 192.229 1.00 130.66 ? 425 VAL A CA  1 
ATOM   3221  C  C   . VAL A 1 425 ? 232.951 181.493 193.635 1.00 134.87 ? 425 VAL A C   1 
ATOM   3222  O  O   . VAL A 1 425 ? 234.126 181.660 193.984 1.00 136.00 ? 425 VAL A O   1 
ATOM   3223  C  CB  . VAL A 1 425 ? 232.353 182.188 191.270 1.00 128.36 ? 425 VAL A CB  1 
ATOM   3224  C  CG1 . VAL A 1 425 ? 233.624 183.006 191.079 1.00 128.73 ? 425 VAL A CG1 1 
ATOM   3225  C  CG2 . VAL A 1 425 ? 231.836 181.674 189.938 1.00 125.66 ? 425 VAL A CG2 1 
ATOM   3226  N  N   . ILE A 1 426 ? 231.927 181.722 194.462 1.00 135.10 ? 426 ILE A N   1 
ATOM   3227  C  CA  . ILE A 1 426 ? 232.158 182.098 195.855 1.00 133.66 ? 426 ILE A CA  1 
ATOM   3228  C  C   . ILE A 1 426 ? 232.938 181.003 196.568 1.00 136.03 ? 426 ILE A C   1 
ATOM   3229  O  O   . ILE A 1 426 ? 233.912 181.268 197.283 1.00 135.23 ? 426 ILE A O   1 
ATOM   3230  C  CB  . ILE A 1 426 ? 230.821 182.381 196.564 1.00 131.60 ? 426 ILE A CB  1 
ATOM   3231  C  CG1 . ILE A 1 426 ? 230.223 183.705 196.090 1.00 128.86 ? 426 ILE A CG1 1 
ATOM   3232  C  CG2 . ILE A 1 426 ? 231.005 182.394 198.075 1.00 131.69 ? 426 ILE A CG2 1 
ATOM   3233  C  CD1 . ILE A 1 426 ? 228.742 183.842 196.375 1.00 121.72 ? 426 ILE A CD1 1 
ATOM   3234  N  N   . ASP A 1 427 ? 232.520 179.752 196.374 1.00 138.52 ? 427 ASP A N   1 
ATOM   3235  C  CA  . ASP A 1 427 ? 233.226 178.627 196.973 1.00 141.59 ? 427 ASP A CA  1 
ATOM   3236  C  C   . ASP A 1 427 ? 234.628 178.455 196.403 1.00 140.17 ? 427 ASP A C   1 
ATOM   3237  O  O   . ASP A 1 427 ? 235.510 177.949 197.104 1.00 138.48 ? 427 ASP A O   1 
ATOM   3238  C  CB  . ASP A 1 427 ? 232.422 177.340 196.779 1.00 138.50 ? 427 ASP A CB  1 
ATOM   3239  C  CG  . ASP A 1 427 ? 231.163 177.307 197.623 1.00 138.52 ? 427 ASP A CG  1 
ATOM   3240  O  OD1 . ASP A 1 427 ? 231.033 178.152 198.534 1.00 138.82 ? 427 ASP A OD1 1 
ATOM   3241  O  OD2 . ASP A 1 427 ? 230.302 176.437 197.374 1.00 138.64 ? 427 ASP A OD2 1 
ATOM   3242  N  N   . SER A 1 428 ? 234.853 178.862 195.153 1.00 138.95 ? 428 SER A N   1 
ATOM   3243  C  CA  . SER A 1 428 ? 236.141 178.674 194.494 1.00 136.75 ? 428 SER A CA  1 
ATOM   3244  C  C   . SER A 1 428 ? 237.032 179.907 194.601 1.00 136.18 ? 428 SER A C   1 
ATOM   3245  O  O   . SER A 1 428 ? 238.131 179.835 195.158 1.00 134.55 ? 428 SER A O   1 
ATOM   3246  C  CB  . SER A 1 428 ? 235.928 178.305 193.022 1.00 133.43 ? 428 SER A CB  1 
ATOM   3247  O  OG  . SER A 1 428 ? 235.316 179.370 192.321 1.00 129.42 ? 428 SER A OG  1 
ATOM   3248  N  N   . LEU A 1 429 ? 236.577 181.044 194.074 1.00 135.09 ? 429 LEU A N   1 
ATOM   3249  C  CA  . LEU A 1 429 ? 237.407 182.236 193.999 1.00 133.40 ? 429 LEU A CA  1 
ATOM   3250  C  C   . LEU A 1 429 ? 237.078 183.289 195.047 1.00 135.39 ? 429 LEU A C   1 
ATOM   3251  O  O   . LEU A 1 429 ? 237.657 184.380 195.003 1.00 134.63 ? 429 LEU A O   1 
ATOM   3252  C  CB  . LEU A 1 429 ? 237.311 182.859 192.600 1.00 130.23 ? 429 LEU A CB  1 
ATOM   3253  C  CG  . LEU A 1 429 ? 237.834 181.952 191.485 1.00 127.89 ? 429 LEU A CG  1 
ATOM   3254  C  CD1 . LEU A 1 429 ? 237.918 182.700 190.168 1.00 129.17 ? 429 LEU A CD1 1 
ATOM   3255  C  CD2 . LEU A 1 429 ? 239.185 181.367 191.859 1.00 128.22 ? 429 LEU A CD2 1 
ATOM   3256  N  N   . GLY A 1 430 ? 236.177 183.004 195.977 1.00 136.16 ? 430 GLY A N   1 
ATOM   3257  C  CA  . GLY A 1 430 ? 235.943 183.900 197.089 1.00 134.03 ? 430 GLY A CA  1 
ATOM   3258  C  C   . GLY A 1 430 ? 235.103 185.109 196.733 1.00 132.94 ? 430 GLY A C   1 
ATOM   3259  O  O   . GLY A 1 430 ? 234.496 185.213 195.663 1.00 132.49 ? 430 GLY A O   1 
ATOM   3260  N  N   . TYR A 1 431 ? 235.077 186.051 197.678 1.00 129.97 ? 431 TYR A N   1 
ATOM   3261  C  CA  . TYR A 1 431 ? 234.231 187.231 197.532 1.00 127.76 ? 431 TYR A CA  1 
ATOM   3262  C  C   . TYR A 1 431 ? 234.827 188.245 196.565 1.00 123.25 ? 431 TYR A C   1 
ATOM   3263  O  O   . TYR A 1 431 ? 234.082 189.001 195.927 1.00 120.62 ? 431 TYR A O   1 
ATOM   3264  C  CB  . TYR A 1 431 ? 233.999 187.879 198.898 1.00 126.39 ? 431 TYR A CB  1 
ATOM   3265  C  CG  . TYR A 1 431 ? 232.998 187.157 199.776 1.00 131.69 ? 431 TYR A CG  1 
ATOM   3266  C  CD1 . TYR A 1 431 ? 232.915 185.770 199.781 1.00 133.36 ? 431 TYR A CD1 1 
ATOM   3267  C  CD2 . TYR A 1 431 ? 232.137 187.865 200.603 1.00 133.44 ? 431 TYR A CD2 1 
ATOM   3268  C  CE1 . TYR A 1 431 ? 232.003 185.110 200.582 1.00 135.19 ? 431 TYR A CE1 1 
ATOM   3269  C  CE2 . TYR A 1 431 ? 231.220 187.213 201.408 1.00 137.14 ? 431 TYR A CE2 1 
ATOM   3270  C  CZ  . TYR A 1 431 ? 231.158 185.836 201.393 1.00 137.55 ? 431 TYR A CZ  1 
ATOM   3271  O  OH  . TYR A 1 431 ? 230.249 185.181 202.192 1.00 136.30 ? 431 TYR A OH  1 
ATOM   3272  N  N   . ALA A 1 432 ? 236.158 188.268 196.437 1.00 124.85 ? 432 ALA A N   1 
ATOM   3273  C  CA  . ALA A 1 432 ? 236.833 189.283 195.633 1.00 125.44 ? 432 ALA A CA  1 
ATOM   3274  C  C   . ALA A 1 432 ? 236.408 189.252 194.173 1.00 124.02 ? 432 ALA A C   1 
ATOM   3275  O  O   . ALA A 1 432 ? 236.525 190.269 193.481 1.00 120.30 ? 432 ALA A O   1 
ATOM   3276  C  CB  . ALA A 1 432 ? 238.349 189.109 195.732 1.00 126.39 ? 432 ALA A CB  1 
ATOM   3277  N  N   . TRP A 1 433 ? 235.929 188.113 193.689 1.00 126.91 ? 433 TRP A N   1 
ATOM   3278  C  CA  . TRP A 1 433 ? 235.376 188.003 192.347 1.00 126.85 ? 433 TRP A CA  1 
ATOM   3279  C  C   . TRP A 1 433 ? 233.858 188.102 192.336 1.00 122.61 ? 433 TRP A C   1 
ATOM   3280  O  O   . TRP A 1 433 ? 233.285 188.669 191.401 1.00 120.29 ? 433 TRP A O   1 
ATOM   3281  C  CB  . TRP A 1 433 ? 235.804 186.678 191.703 1.00 133.46 ? 433 TRP A CB  1 
ATOM   3282  C  CG  . TRP A 1 433 ? 237.293 186.434 191.701 1.00 139.04 ? 433 TRP A CG  1 
ATOM   3283  C  CD1 . TRP A 1 433 ? 238.118 186.358 192.788 1.00 137.47 ? 433 TRP A CD1 1 
ATOM   3284  C  CD2 . TRP A 1 433 ? 238.125 186.217 190.554 1.00 143.46 ? 433 TRP A CD2 1 
ATOM   3285  N  NE1 . TRP A 1 433 ? 239.409 186.117 192.389 1.00 140.16 ? 433 TRP A NE1 1 
ATOM   3286  C  CE2 . TRP A 1 433 ? 239.441 186.025 191.022 1.00 144.49 ? 433 TRP A CE2 1 
ATOM   3287  C  CE3 . TRP A 1 433 ? 237.886 186.169 189.178 1.00 140.38 ? 433 TRP A CE3 1 
ATOM   3288  C  CZ2 . TRP A 1 433 ? 240.512 185.790 190.164 1.00 143.11 ? 433 TRP A CZ2 1 
ATOM   3289  C  CZ3 . TRP A 1 433 ? 238.952 185.936 188.327 1.00 140.67 ? 433 TRP A CZ3 1 
ATOM   3290  C  CH2 . TRP A 1 433 ? 240.247 185.750 188.823 1.00 142.24 ? 433 TRP A CH2 1 
ATOM   3291  N  N   . ALA A 1 434 ? 233.202 187.552 193.362 1.00 121.71 ? 434 ALA A N   1 
ATOM   3292  C  CA  . ALA A 1 434 ? 231.743 187.520 193.396 1.00 118.10 ? 434 ALA A CA  1 
ATOM   3293  C  C   . ALA A 1 434 ? 231.163 188.924 193.461 1.00 111.66 ? 434 ALA A C   1 
ATOM   3294  O  O   . ALA A 1 434 ? 230.184 189.241 192.770 1.00 108.31 ? 434 ALA A O   1 
ATOM   3295  C  CB  . ALA A 1 434 ? 231.270 186.696 194.590 1.00 115.60 ? 434 ALA A CB  1 
ATOM   3296  N  N   . ASP A 1 435 ? 231.750 189.778 194.297 1.00 110.18 ? 435 ASP A N   1 
ATOM   3297  C  CA  . ASP A 1 435 ? 231.258 191.144 194.403 1.00 108.71 ? 435 ASP A CA  1 
ATOM   3298  C  C   . ASP A 1 435 ? 231.365 191.861 193.064 1.00 106.03 ? 435 ASP A C   1 
ATOM   3299  O  O   . ASP A 1 435 ? 230.414 192.512 192.617 1.00 103.68 ? 435 ASP A O   1 
ATOM   3300  C  CB  . ASP A 1 435 ? 232.027 191.889 195.493 1.00 110.55 ? 435 ASP A CB  1 
ATOM   3301  C  CG  . ASP A 1 435 ? 231.468 191.627 196.878 1.00 108.45 ? 435 ASP A CG  1 
ATOM   3302  O  OD1 . ASP A 1 435 ? 230.414 190.965 196.977 1.00 105.35 ? 435 ASP A OD1 1 
ATOM   3303  O  OD2 . ASP A 1 435 ? 232.079 192.084 197.866 1.00 109.88 ? 435 ASP A OD2 1 
ATOM   3304  N  N   . GLN A 1 436 ? 232.507 191.721 192.391 1.00 107.88 ? 436 GLN A N   1 
ATOM   3305  C  CA  . GLN A 1 436 ? 232.687 192.374 191.100 1.00 105.83 ? 436 GLN A CA  1 
ATOM   3306  C  C   . GLN A 1 436 ? 231.687 191.850 190.080 1.00 103.82 ? 436 GLN A C   1 
ATOM   3307  O  O   . GLN A 1 436 ? 231.083 192.628 189.328 1.00 102.06 ? 436 GLN A O   1 
ATOM   3308  C  CB  . GLN A 1 436 ? 234.117 192.168 190.606 1.00 111.86 ? 436 GLN A CB  1 
ATOM   3309  C  CG  . GLN A 1 436 ? 235.171 192.824 191.479 1.00 117.59 ? 436 GLN A CG  1 
ATOM   3310  C  CD  . GLN A 1 436 ? 236.567 192.325 191.174 1.00 124.34 ? 436 GLN A CD  1 
ATOM   3311  O  OE1 . GLN A 1 436 ? 236.748 191.398 190.385 1.00 126.21 ? 436 GLN A OE1 1 
ATOM   3312  N  NE2 . GLN A 1 436 ? 237.565 192.942 191.795 1.00 122.16 ? 436 GLN A NE2 1 
ATOM   3313  N  N   . ALA A 1 437 ? 231.497 190.527 190.045 1.00 108.51 ? 437 ALA A N   1 
ATOM   3314  C  CA  . ALA A 1 437 ? 230.588 189.927 189.075 1.00 108.28 ? 437 ALA A CA  1 
ATOM   3315  C  C   . ALA A 1 437 ? 229.170 190.439 189.274 1.00 101.36 ? 437 ALA A C   1 
ATOM   3316  O  O   . ALA A 1 437 ? 228.492 190.828 188.313 1.00 100.71 ? 437 ALA A O   1 
ATOM   3317  C  CB  . ALA A 1 437 ? 230.633 188.403 189.185 1.00 109.79 ? 437 ALA A CB  1 
ATOM   3318  N  N   . LEU A 1 438 ? 228.711 190.460 190.526 1.00 97.15  ? 438 LEU A N   1 
ATOM   3319  C  CA  . LEU A 1 438 ? 227.386 190.995 190.799 1.00 88.89  ? 438 LEU A CA  1 
ATOM   3320  C  C   . LEU A 1 438 ? 227.320 192.475 190.447 1.00 89.59  ? 438 LEU A C   1 
ATOM   3321  O  O   . LEU A 1 438 ? 226.271 192.968 190.004 1.00 92.12  ? 438 LEU A O   1 
ATOM   3322  C  CB  . LEU A 1 438 ? 227.022 190.736 192.260 1.00 82.57  ? 438 LEU A CB  1 
ATOM   3323  C  CG  . LEU A 1 438 ? 225.541 190.690 192.625 1.00 74.63  ? 438 LEU A CG  1 
ATOM   3324  C  CD1 . LEU A 1 438 ? 225.355 189.884 193.882 1.00 71.83  ? 438 LEU A CD1 1 
ATOM   3325  C  CD2 . LEU A 1 438 ? 225.016 192.089 192.836 1.00 72.27  ? 438 LEU A CD2 1 
ATOM   3326  N  N   . LEU A 1 439 ? 228.441 193.183 190.586 1.00 90.40  ? 439 LEU A N   1 
ATOM   3327  C  CA  . LEU A 1 439 ? 228.470 194.588 190.208 1.00 87.78  ? 439 LEU A CA  1 
ATOM   3328  C  C   . LEU A 1 439 ? 228.161 194.764 188.729 1.00 86.13  ? 439 LEU A C   1 
ATOM   3329  O  O   . LEU A 1 439 ? 227.274 195.544 188.362 1.00 85.60  ? 439 LEU A O   1 
ATOM   3330  C  CB  . LEU A 1 439 ? 229.827 195.201 190.551 1.00 96.26  ? 439 LEU A CB  1 
ATOM   3331  C  CG  . LEU A 1 439 ? 230.032 195.710 191.980 1.00 98.77  ? 439 LEU A CG  1 
ATOM   3332  C  CD1 . LEU A 1 439 ? 231.515 195.867 192.283 1.00 99.73  ? 439 LEU A CD1 1 
ATOM   3333  C  CD2 . LEU A 1 439 ? 229.298 197.024 192.191 1.00 88.05  ? 439 LEU A CD2 1 
ATOM   3334  N  N   . GLU A 1 440 ? 228.876 194.048 187.854 1.00 89.46  ? 440 GLU A N   1 
ATOM   3335  C  CA  . GLU A 1 440 ? 228.565 194.305 186.446 1.00 88.14  ? 440 GLU A CA  1 
ATOM   3336  C  C   . GLU A 1 440 ? 227.255 193.658 186.026 1.00 83.48  ? 440 GLU A C   1 
ATOM   3337  O  O   . GLU A 1 440 ? 226.676 194.080 185.023 1.00 82.43  ? 440 GLU A O   1 
ATOM   3338  C  CB  . GLU A 1 440 ? 229.641 193.867 185.434 1.00 92.11  ? 440 GLU A CB  1 
ATOM   3339  C  CG  . GLU A 1 440 ? 231.095 194.051 185.797 1.00 100.86 ? 440 GLU A CG  1 
ATOM   3340  C  CD  . GLU A 1 440 ? 231.612 192.869 186.555 1.00 109.97 ? 440 GLU A CD  1 
ATOM   3341  O  OE1 . GLU A 1 440 ? 230.771 192.034 186.927 1.00 107.39 ? 440 GLU A OE1 1 
ATOM   3342  O  OE2 . GLU A 1 440 ? 232.837 192.774 186.784 1.00 115.27 ? 440 GLU A OE2 1 
ATOM   3343  N  N   . VAL A 1 441 ? 226.758 192.670 186.770 1.00 80.54  ? 441 VAL A N   1 
ATOM   3344  C  CA  . VAL A 1 441 ? 225.406 192.183 186.508 1.00 74.54  ? 441 VAL A CA  1 
ATOM   3345  C  C   . VAL A 1 441 ? 224.400 193.309 186.703 1.00 75.71  ? 441 VAL A C   1 
ATOM   3346  O  O   . VAL A 1 441 ? 223.542 193.563 185.846 1.00 78.02  ? 441 VAL A O   1 
ATOM   3347  C  CB  . VAL A 1 441 ? 225.087 190.979 187.410 1.00 76.22  ? 441 VAL A CB  1 
ATOM   3348  C  CG1 . VAL A 1 441 ? 223.591 190.850 187.606 1.00 77.49  ? 441 VAL A CG1 1 
ATOM   3349  C  CG2 . VAL A 1 441 ? 225.642 189.716 186.806 1.00 76.78  ? 441 VAL A CG2 1 
ATOM   3350  N  N   . VAL A 1 442 ? 224.508 194.022 187.827 1.00 78.03  ? 442 VAL A N   1 
ATOM   3351  C  CA  . VAL A 1 442 ? 223.601 195.141 188.061 1.00 73.73  ? 442 VAL A CA  1 
ATOM   3352  C  C   . VAL A 1 442 ? 223.826 196.233 187.029 1.00 74.49  ? 442 VAL A C   1 
ATOM   3353  O  O   . VAL A 1 442 ? 222.877 196.878 186.567 1.00 73.45  ? 442 VAL A O   1 
ATOM   3354  C  CB  . VAL A 1 442 ? 223.754 195.680 189.491 1.00 72.02  ? 442 VAL A CB  1 
ATOM   3355  C  CG1 . VAL A 1 442 ? 222.756 196.775 189.732 1.00 64.23  ? 442 VAL A CG1 1 
ATOM   3356  C  CG2 . VAL A 1 442 ? 223.554 194.572 190.490 1.00 70.86  ? 442 VAL A CG2 1 
ATOM   3357  N  N   . ASN A 1 443 ? 225.084 196.465 186.652 1.00 79.01  ? 443 ASN A N   1 
ATOM   3358  C  CA  . ASN A 1 443 ? 225.369 197.490 185.654 1.00 80.91  ? 443 ASN A CA  1 
ATOM   3359  C  C   . ASN A 1 443 ? 224.695 197.165 184.329 1.00 78.20  ? 443 ASN A C   1 
ATOM   3360  O  O   . ASN A 1 443 ? 224.103 198.044 183.692 1.00 79.09  ? 443 ASN A O   1 
ATOM   3361  C  CB  . ASN A 1 443 ? 226.879 197.635 185.467 1.00 84.72  ? 443 ASN A CB  1 
ATOM   3362  C  CG  . ASN A 1 443 ? 227.556 198.285 186.658 1.00 85.99  ? 443 ASN A CG  1 
ATOM   3363  O  OD1 . ASN A 1 443 ? 226.924 199.009 187.428 1.00 87.04  ? 443 ASN A OD1 1 
ATOM   3364  N  ND2 . ASN A 1 443 ? 228.849 198.028 186.816 1.00 86.35  ? 443 ASN A ND2 1 
ATOM   3365  N  N   . ARG A 1 444 ? 224.766 195.903 183.904 1.00 76.68  ? 444 ARG A N   1 
ATOM   3366  C  CA  . ARG A 1 444 ? 224.091 195.494 182.680 1.00 78.62  ? 444 ARG A CA  1 
ATOM   3367  C  C   . ARG A 1 444 ? 222.583 195.643 182.814 1.00 78.84  ? 444 ARG A C   1 
ATOM   3368  O  O   . ARG A 1 444 ? 221.905 196.022 181.852 1.00 81.12  ? 444 ARG A O   1 
ATOM   3369  C  CB  . ARG A 1 444 ? 224.457 194.052 182.336 1.00 76.81  ? 444 ARG A CB  1 
ATOM   3370  C  CG  . ARG A 1 444 ? 225.878 193.862 181.831 1.00 80.12  ? 444 ARG A CG  1 
ATOM   3371  C  CD  . ARG A 1 444 ? 226.131 192.412 181.439 1.00 84.46  ? 444 ARG A CD  1 
ATOM   3372  N  NE  . ARG A 1 444 ? 227.554 192.101 181.373 1.00 90.43  ? 444 ARG A NE  1 
ATOM   3373  C  CZ  . ARG A 1 444 ? 228.046 190.891 181.150 1.00 94.22  ? 444 ARG A CZ  1 
ATOM   3374  N  NH1 . ARG A 1 444 ? 227.256 189.849 180.958 1.00 91.36  ? 444 ARG A NH1 1 
ATOM   3375  N  NH2 . ARG A 1 444 ? 229.364 190.720 181.130 1.00 101.49 ? 444 ARG A NH2 1 
ATOM   3376  N  N   . PHE A 1 445 ? 222.036 195.334 183.993 1.00 76.70  ? 445 PHE A N   1 
ATOM   3377  C  CA  . PHE A 1 445 ? 220.596 195.487 184.189 1.00 71.47  ? 445 PHE A CA  1 
ATOM   3378  C  C   . PHE A 1 445 ? 220.175 196.936 184.015 1.00 72.44  ? 445 PHE A C   1 
ATOM   3379  O  O   . PHE A 1 445 ? 219.209 197.233 183.306 1.00 75.44  ? 445 PHE A O   1 
ATOM   3380  C  CB  . PHE A 1 445 ? 220.183 195.003 185.577 1.00 68.51  ? 445 PHE A CB  1 
ATOM   3381  C  CG  . PHE A 1 445 ? 219.900 193.541 185.654 1.00 64.80  ? 445 PHE A CG  1 
ATOM   3382  C  CD1 . PHE A 1 445 ? 219.790 192.780 184.512 1.00 66.89  ? 445 PHE A CD1 1 
ATOM   3383  C  CD2 . PHE A 1 445 ? 219.759 192.925 186.875 1.00 60.93  ? 445 PHE A CD2 1 
ATOM   3384  C  CE1 . PHE A 1 445 ? 219.543 191.430 184.594 1.00 67.60  ? 445 PHE A CE1 1 
ATOM   3385  C  CE2 . PHE A 1 445 ? 219.515 191.584 186.963 1.00 60.19  ? 445 PHE A CE2 1 
ATOM   3386  C  CZ  . PHE A 1 445 ? 219.403 190.833 185.824 1.00 65.73  ? 445 PHE A CZ  1 
ATOM   3387  N  N   . ARG A 1 446 ? 220.896 197.855 184.659 1.00 70.45  ? 446 ARG A N   1 
ATOM   3388  C  CA  . ARG A 1 446 ? 220.477 199.252 184.656 1.00 70.90  ? 446 ARG A CA  1 
ATOM   3389  C  C   . ARG A 1 446 ? 220.498 199.841 183.253 1.00 72.74  ? 446 ARG A C   1 
ATOM   3390  O  O   . ARG A 1 446 ? 219.772 200.800 182.971 1.00 71.12  ? 446 ARG A O   1 
ATOM   3391  C  CB  . ARG A 1 446 ? 221.375 200.067 185.582 1.00 69.31  ? 446 ARG A CB  1 
ATOM   3392  C  CG  . ARG A 1 446 ? 220.891 200.168 187.014 1.00 66.81  ? 446 ARG A CG  1 
ATOM   3393  C  CD  . ARG A 1 446 ? 221.818 201.070 187.806 1.00 68.97  ? 446 ARG A CD  1 
ATOM   3394  N  NE  . ARG A 1 446 ? 221.504 201.095 189.227 1.00 63.19  ? 446 ARG A NE  1 
ATOM   3395  C  CZ  . ARG A 1 446 ? 222.416 201.113 190.188 1.00 59.33  ? 446 ARG A CZ  1 
ATOM   3396  N  NH1 . ARG A 1 446 ? 223.709 201.111 189.913 1.00 59.17  ? 446 ARG A NH1 1 
ATOM   3397  N  NH2 . ARG A 1 446 ? 222.021 201.139 191.456 1.00 57.32  ? 446 ARG A NH2 1 
ATOM   3398  N  N   . GLU A 1 447 ? 221.314 199.280 182.363 1.00 76.47  ? 447 GLU A N   1 
ATOM   3399  C  CA  . GLU A 1 447 ? 221.384 199.781 181.001 1.00 78.15  ? 447 GLU A CA  1 
ATOM   3400  C  C   . GLU A 1 447 ? 220.114 199.496 180.218 1.00 77.73  ? 447 GLU A C   1 
ATOM   3401  O  O   . GLU A 1 447 ? 219.904 200.096 179.160 1.00 81.39  ? 447 GLU A O   1 
ATOM   3402  C  CB  . GLU A 1 447 ? 222.584 199.169 180.281 1.00 84.90  ? 447 GLU A CB  1 
ATOM   3403  C  CG  . GLU A 1 447 ? 223.919 199.761 180.692 1.00 89.07  ? 447 GLU A CG  1 
ATOM   3404  C  CD  . GLU A 1 447 ? 225.083 199.149 179.939 1.00 95.66  ? 447 GLU A CD  1 
ATOM   3405  O  OE1 . GLU A 1 447 ? 224.869 198.147 179.226 1.00 97.95  ? 447 GLU A OE1 1 
ATOM   3406  O  OE2 . GLU A 1 447 ? 226.211 199.671 180.061 1.00 96.11  ? 447 GLU A OE2 1 
ATOM   3407  N  N   . LYS A 1 448 ? 219.264 198.599 180.709 1.00 76.12  ? 448 LYS A N   1 
ATOM   3408  C  CA  . LYS A 1 448 ? 218.019 198.256 180.038 1.00 75.86  ? 448 LYS A CA  1 
ATOM   3409  C  C   . LYS A 1 448 ? 216.814 198.449 180.950 1.00 71.23  ? 448 LYS A C   1 
ATOM   3410  O  O   . LYS A 1 448 ? 215.885 197.643 180.937 1.00 74.03  ? 448 LYS A O   1 
ATOM   3411  C  CB  . LYS A 1 448 ? 218.068 196.824 179.510 1.00 76.85  ? 448 LYS A CB  1 
ATOM   3412  C  CG  . LYS A 1 448 ? 218.387 196.743 178.022 1.00 76.60  ? 448 LYS A CG  1 
ATOM   3413  C  CD  . LYS A 1 448 ? 218.406 195.312 177.502 1.00 78.19  ? 448 LYS A CD  1 
ATOM   3414  C  CE  . LYS A 1 448 ? 219.058 194.347 178.476 1.00 77.82  ? 448 LYS A CE  1 
ATOM   3415  N  NZ  . LYS A 1 448 ? 220.429 194.772 178.880 1.00 76.96  ? 448 LYS A NZ  1 
ATOM   3416  N  N   . LEU A 1 449 ? 216.810 199.507 181.749 1.00 65.44  ? 449 LEU A N   1 
ATOM   3417  C  CA  . LEU A 1 449 ? 215.637 199.782 182.554 1.00 64.34  ? 449 LEU A CA  1 
ATOM   3418  C  C   . LEU A 1 449 ? 214.642 200.643 181.781 1.00 64.09  ? 449 LEU A C   1 
ATOM   3419  O  O   . LEU A 1 449 ? 214.823 200.956 180.605 1.00 61.79  ? 449 LEU A O   1 
ATOM   3420  C  CB  . LEU A 1 449 ? 216.020 200.454 183.869 1.00 66.07  ? 449 LEU A CB  1 
ATOM   3421  C  CG  . LEU A 1 449 ? 215.889 199.576 185.116 1.00 66.50  ? 449 LEU A CG  1 
ATOM   3422  C  CD1 . LEU A 1 449 ? 216.820 198.387 185.048 1.00 68.02  ? 449 LEU A CD1 1 
ATOM   3423  C  CD2 . LEU A 1 449 ? 216.141 200.381 186.375 1.00 64.79  ? 449 LEU A CD2 1 
ATOM   3424  N  N   . LYS A 1 450 ? 213.557 200.989 182.456 1.00 67.02  ? 450 LYS A N   1 
ATOM   3425  C  CA  . LYS A 1 450 ? 212.490 201.812 181.915 1.00 66.78  ? 450 LYS A CA  1 
ATOM   3426  C  C   . LYS A 1 450 ? 211.986 202.697 183.042 1.00 67.21  ? 450 LYS A C   1 
ATOM   3427  O  O   . LYS A 1 450 ? 212.150 202.358 184.218 1.00 68.02  ? 450 LYS A O   1 
ATOM   3428  C  CB  . LYS A 1 450 ? 211.360 200.940 181.351 1.00 70.05  ? 450 LYS A CB  1 
ATOM   3429  C  CG  . LYS A 1 450 ? 210.692 201.473 180.095 1.00 76.36  ? 450 LYS A CG  1 
ATOM   3430  C  CD  . LYS A 1 450 ? 209.925 200.384 179.369 1.00 82.76  ? 450 LYS A CD  1 
ATOM   3431  C  CE  . LYS A 1 450 ? 210.843 199.237 178.983 1.00 81.47  ? 450 LYS A CE  1 
ATOM   3432  N  NZ  . LYS A 1 450 ? 211.981 199.700 178.143 1.00 82.49  ? 450 LYS A NZ  1 
ATOM   3433  N  N   . PRO A 1 451 ? 211.396 203.850 182.721 1.00 66.35  ? 451 PRO A N   1 
ATOM   3434  C  CA  . PRO A 1 451 ? 210.905 204.725 183.798 1.00 68.35  ? 451 PRO A CA  1 
ATOM   3435  C  C   . PRO A 1 451 ? 209.895 204.065 184.718 1.00 74.15  ? 451 PRO A C   1 
ATOM   3436  O  O   . PRO A 1 451 ? 209.845 204.398 185.909 1.00 78.85  ? 451 PRO A O   1 
ATOM   3437  C  CB  . PRO A 1 451 ? 210.294 205.903 183.032 1.00 67.48  ? 451 PRO A CB  1 
ATOM   3438  C  CG  . PRO A 1 451 ? 211.043 205.938 181.763 1.00 70.42  ? 451 PRO A CG  1 
ATOM   3439  C  CD  . PRO A 1 451 ? 211.329 204.516 181.411 1.00 68.61  ? 451 PRO A CD  1 
ATOM   3440  N  N   . ASP A 1 452 ? 209.089 203.138 184.212 1.00 73.47  ? 452 ASP A N   1 
ATOM   3441  C  CA  . ASP A 1 452 ? 208.103 202.453 185.035 1.00 68.88  ? 452 ASP A CA  1 
ATOM   3442  C  C   . ASP A 1 452 ? 208.647 201.198 185.706 1.00 69.09  ? 452 ASP A C   1 
ATOM   3443  O  O   . ASP A 1 452 ? 207.924 200.571 186.485 1.00 69.81  ? 452 ASP A O   1 
ATOM   3444  C  CB  . ASP A 1 452 ? 206.880 202.089 184.193 1.00 73.61  ? 452 ASP A CB  1 
ATOM   3445  C  CG  . ASP A 1 452 ? 207.252 201.619 182.802 1.00 79.53  ? 452 ASP A CG  1 
ATOM   3446  O  OD1 . ASP A 1 452 ? 207.814 202.425 182.032 1.00 79.87  ? 452 ASP A OD1 1 
ATOM   3447  O  OD2 . ASP A 1 452 ? 206.983 200.443 182.479 1.00 81.71  ? 452 ASP A OD2 1 
ATOM   3448  N  N   . GLN A 1 453 ? 209.894 200.820 185.436 1.00 69.37  ? 453 GLN A N   1 
ATOM   3449  C  CA  . GLN A 1 453 ? 210.471 199.588 185.957 1.00 66.67  ? 453 GLN A CA  1 
ATOM   3450  C  C   . GLN A 1 453 ? 211.305 199.880 187.196 1.00 66.52  ? 453 GLN A C   1 
ATOM   3451  O  O   . GLN A 1 453 ? 212.229 200.697 187.150 1.00 68.02  ? 453 GLN A O   1 
ATOM   3452  C  CB  . GLN A 1 453 ? 211.326 198.903 184.896 1.00 63.04  ? 453 GLN A CB  1 
ATOM   3453  C  CG  . GLN A 1 453 ? 210.519 198.350 183.750 1.00 65.85  ? 453 GLN A CG  1 
ATOM   3454  C  CD  . GLN A 1 453 ? 211.253 197.265 183.005 1.00 70.30  ? 453 GLN A CD  1 
ATOM   3455  O  OE1 . GLN A 1 453 ? 212.400 196.954 183.315 1.00 72.08  ? 453 GLN A OE1 1 
ATOM   3456  N  NE2 . GLN A 1 453 ? 210.598 196.683 182.011 1.00 70.84  ? 453 GLN A NE2 1 
ATOM   3457  N  N   . TYR A 1 454 ? 210.984 199.198 188.293 1.00 61.88  ? 454 TYR A N   1 
ATOM   3458  C  CA  . TYR A 1 454 ? 211.562 199.476 189.604 1.00 54.30  ? 454 TYR A CA  1 
ATOM   3459  C  C   . TYR A 1 454 ? 212.381 198.274 190.053 1.00 50.90  ? 454 TYR A C   1 
ATOM   3460  O  O   . TYR A 1 454 ? 211.837 197.179 190.203 1.00 55.91  ? 454 TYR A O   1 
ATOM   3461  C  CB  . TYR A 1 454 ? 210.444 199.781 190.602 1.00 61.00  ? 454 TYR A CB  1 
ATOM   3462  C  CG  . TYR A 1 454 ? 210.847 199.782 192.056 1.00 64.78  ? 454 TYR A CG  1 
ATOM   3463  C  CD1 . TYR A 1 454 ? 211.357 200.920 192.655 1.00 63.80  ? 454 TYR A CD1 1 
ATOM   3464  C  CD2 . TYR A 1 454 ? 210.700 198.648 192.834 1.00 66.56  ? 454 TYR A CD2 1 
ATOM   3465  C  CE1 . TYR A 1 454 ? 211.719 200.922 193.983 1.00 67.27  ? 454 TYR A CE1 1 
ATOM   3466  C  CE2 . TYR A 1 454 ? 211.060 198.643 194.162 1.00 70.24  ? 454 TYR A CE2 1 
ATOM   3467  C  CZ  . TYR A 1 454 ? 211.569 199.781 194.730 1.00 71.63  ? 454 TYR A CZ  1 
ATOM   3468  O  OH  . TYR A 1 454 ? 211.929 199.780 196.057 1.00 73.42  ? 454 TYR A OH  1 
ATOM   3469  N  N   . LEU A 1 455 ? 213.672 198.472 190.282 1.00 46.34  ? 455 LEU A N   1 
ATOM   3470  C  CA  . LEU A 1 455 ? 214.544 197.377 190.674 1.00 45.72  ? 455 LEU A CA  1 
ATOM   3471  C  C   . LEU A 1 455 ? 214.881 197.485 192.155 1.00 53.95  ? 455 LEU A C   1 
ATOM   3472  O  O   . LEU A 1 455 ? 215.008 198.582 192.704 1.00 60.16  ? 455 LEU A O   1 
ATOM   3473  C  CB  . LEU A 1 455 ? 215.828 197.366 189.850 1.00 36.78  ? 455 LEU A CB  1 
ATOM   3474  C  CG  . LEU A 1 455 ? 216.654 196.083 189.819 1.00 34.96  ? 455 LEU A CG  1 
ATOM   3475  C  CD1 . LEU A 1 455 ? 215.900 194.991 189.119 1.00 41.64  ? 455 LEU A CD1 1 
ATOM   3476  C  CD2 . LEU A 1 455 ? 217.957 196.317 189.123 1.00 35.43  ? 455 LEU A CD2 1 
ATOM   3477  N  N   . CYS A 1 456 ? 215.020 196.328 192.796 1.00 49.85  ? 456 CYS A N   1 
ATOM   3478  C  CA  . CYS A 1 456 ? 215.369 196.248 194.205 1.00 48.21  ? 456 CYS A CA  1 
ATOM   3479  C  C   . CYS A 1 456 ? 216.266 195.042 194.411 1.00 50.22  ? 456 CYS A C   1 
ATOM   3480  O  O   . CYS A 1 456 ? 216.232 194.086 193.638 1.00 55.19  ? 456 CYS A O   1 
ATOM   3481  C  CB  . CYS A 1 456 ? 214.125 196.145 195.080 1.00 53.38  ? 456 CYS A CB  1 
ATOM   3482  S  SG  . CYS A 1 456 ? 214.490 195.841 196.814 1.00 86.98  ? 456 CYS A SG  1 
ATOM   3483  N  N   . ARG A 1 457 ? 217.077 195.091 195.457 1.00 50.67  ? 457 ARG A N   1 
ATOM   3484  C  CA  . ARG A 1 457 ? 217.966 193.985 195.797 1.00 52.80  ? 457 ARG A CA  1 
ATOM   3485  C  C   . ARG A 1 457 ? 217.559 193.458 197.167 1.00 61.61  ? 457 ARG A C   1 
ATOM   3486  O  O   . ARG A 1 457 ? 217.980 194.000 198.192 1.00 66.27  ? 457 ARG A O   1 
ATOM   3487  C  CB  . ARG A 1 457 ? 219.421 194.413 195.786 1.00 51.18  ? 457 ARG A CB  1 
ATOM   3488  C  CG  . ARG A 1 457 ? 220.368 193.246 195.929 1.00 55.36  ? 457 ARG A CG  1 
ATOM   3489  C  CD  . ARG A 1 457 ? 221.434 193.553 196.954 1.00 61.13  ? 457 ARG A CD  1 
ATOM   3490  N  NE  . ARG A 1 457 ? 222.468 192.532 196.997 1.00 64.46  ? 457 ARG A NE  1 
ATOM   3491  C  CZ  . ARG A 1 457 ? 223.765 192.783 197.076 1.00 68.34  ? 457 ARG A CZ  1 
ATOM   3492  N  NH1 . ARG A 1 457 ? 224.227 194.019 197.115 1.00 68.84  ? 457 ARG A NH1 1 
ATOM   3493  N  NH2 . ARG A 1 457 ? 224.621 191.768 197.117 1.00 71.99  ? 457 ARG A NH2 1 
ATOM   3494  N  N   . ILE A 1 458 ? 216.744 192.400 197.183 1.00 59.04  ? 458 ILE A N   1 
ATOM   3495  C  CA  . ILE A 1 458 ? 216.240 191.873 198.447 1.00 59.65  ? 458 ILE A CA  1 
ATOM   3496  C  C   . ILE A 1 458 ? 217.373 191.289 199.275 1.00 62.07  ? 458 ILE A C   1 
ATOM   3497  O  O   . ILE A 1 458 ? 217.528 191.618 200.457 1.00 67.17  ? 458 ILE A O   1 
ATOM   3498  C  CB  . ILE A 1 458 ? 215.142 190.831 198.199 1.00 55.89  ? 458 ILE A CB  1 
ATOM   3499  C  CG1 . ILE A 1 458 ? 215.458 190.007 196.957 1.00 53.89  ? 458 ILE A CG1 1 
ATOM   3500  C  CG2 . ILE A 1 458 ? 213.797 191.501 198.077 1.00 61.12  ? 458 ILE A CG2 1 
ATOM   3501  C  CD1 . ILE A 1 458 ? 214.603 188.773 196.832 1.00 55.03  ? 458 ILE A CD1 1 
ATOM   3502  N  N   . GLU A 1 459 ? 218.192 190.431 198.672 1.00 56.73  ? 459 GLU A N   1 
ATOM   3503  C  CA  . GLU A 1 459 ? 219.221 189.780 199.467 1.00 59.85  ? 459 GLU A CA  1 
ATOM   3504  C  C   . GLU A 1 459 ? 220.242 189.125 198.559 1.00 59.91  ? 459 GLU A C   1 
ATOM   3505  O  O   . GLU A 1 459 ? 219.893 188.617 197.495 1.00 62.64  ? 459 GLU A O   1 
ATOM   3506  C  CB  . GLU A 1 459 ? 218.610 188.740 200.413 1.00 62.22  ? 459 GLU A CB  1 
ATOM   3507  C  CG  . GLU A 1 459 ? 218.272 187.410 199.780 1.00 61.59  ? 459 GLU A CG  1 
ATOM   3508  C  CD  . GLU A 1 459 ? 219.355 186.378 200.002 1.00 68.29  ? 459 GLU A CD  1 
ATOM   3509  O  OE1 . GLU A 1 459 ? 220.371 186.717 200.643 1.00 71.77  ? 459 GLU A OE1 1 
ATOM   3510  O  OE2 . GLU A 1 459 ? 219.190 185.228 199.545 1.00 70.97  ? 459 GLU A OE2 1 
ATOM   3511  N  N   . GLY A 1 460 ? 221.499 189.154 198.994 1.00 60.98  ? 460 GLY A N   1 
ATOM   3512  C  CA  . GLY A 1 460 ? 222.578 188.381 198.413 1.00 62.02  ? 460 GLY A CA  1 
ATOM   3513  C  C   . GLY A 1 460 ? 222.619 188.367 196.905 1.00 68.75  ? 460 GLY A C   1 
ATOM   3514  O  O   . GLY A 1 460 ? 222.866 189.393 196.267 1.00 70.23  ? 460 GLY A O   1 
ATOM   3515  N  N   . THR A 1 461 ? 222.381 187.193 196.327 1.00 68.74  ? 461 THR A N   1 
ATOM   3516  C  CA  . THR A 1 461 ? 222.269 187.014 194.884 1.00 66.44  ? 461 THR A CA  1 
ATOM   3517  C  C   . THR A 1 461 ? 220.822 186.813 194.452 1.00 60.63  ? 461 THR A C   1 
ATOM   3518  O  O   . THR A 1 461 ? 220.513 185.946 193.635 1.00 64.77  ? 461 THR A O   1 
ATOM   3519  C  CB  . THR A 1 461 ? 223.148 185.857 194.431 1.00 78.01  ? 461 THR A CB  1 
ATOM   3520  O  OG1 . THR A 1 461 ? 222.714 184.647 195.062 1.00 84.89  ? 461 THR A OG1 1 
ATOM   3521  C  CG2 . THR A 1 461 ? 224.593 186.134 194.803 1.00 76.81  ? 461 THR A CG2 1 
ATOM   3522  N  N   . GLN A 1 462 ? 219.916 187.598 195.020 1.00 57.96  ? 462 GLN A N   1 
ATOM   3523  C  CA  . GLN A 1 462 ? 218.532 187.681 194.588 1.00 53.98  ? 462 GLN A CA  1 
ATOM   3524  C  C   . GLN A 1 462 ? 218.175 189.139 194.364 1.00 52.54  ? 462 GLN A C   1 
ATOM   3525  O  O   . GLN A 1 462 ? 218.614 190.018 195.111 1.00 59.33  ? 462 GLN A O   1 
ATOM   3526  C  CB  . GLN A 1 462 ? 217.575 187.072 195.619 1.00 60.80  ? 462 GLN A CB  1 
ATOM   3527  C  CG  . GLN A 1 462 ? 217.926 185.670 196.090 1.00 64.82  ? 462 GLN A CG  1 
ATOM   3528  C  CD  . GLN A 1 462 ? 216.937 185.133 197.116 1.00 71.34  ? 462 GLN A CD  1 
ATOM   3529  O  OE1 . GLN A 1 462 ? 215.759 185.485 197.109 1.00 71.55  ? 462 GLN A OE1 1 
ATOM   3530  N  NE2 . GLN A 1 462 ? 217.418 184.272 198.004 1.00 74.15  ? 462 GLN A NE2 1 
ATOM   3531  N  N   . PHE A 1 463 ? 217.379 189.388 193.333 1.00 49.30  ? 463 PHE A N   1 
ATOM   3532  C  CA  . PHE A 1 463 ? 216.893 190.711 192.981 1.00 45.42  ? 463 PHE A CA  1 
ATOM   3533  C  C   . PHE A 1 463 ? 215.393 190.641 192.746 1.00 44.99  ? 463 PHE A C   1 
ATOM   3534  O  O   . PHE A 1 463 ? 214.816 189.565 192.578 1.00 52.64  ? 463 PHE A O   1 
ATOM   3535  C  CB  . PHE A 1 463 ? 217.575 191.248 191.720 1.00 45.60  ? 463 PHE A CB  1 
ATOM   3536  C  CG  . PHE A 1 463 ? 219.069 191.239 191.776 1.00 48.33  ? 463 PHE A CG  1 
ATOM   3537  C  CD1 . PHE A 1 463 ? 219.773 190.068 191.659 1.00 49.96  ? 463 PHE A CD1 1 
ATOM   3538  C  CD2 . PHE A 1 463 ? 219.770 192.414 191.871 1.00 52.76  ? 463 PHE A CD2 1 
ATOM   3539  C  CE1 . PHE A 1 463 ? 221.137 190.063 191.690 1.00 54.45  ? 463 PHE A CE1 1 
ATOM   3540  C  CE2 . PHE A 1 463 ? 221.138 192.412 191.896 1.00 59.22  ? 463 PHE A CE2 1 
ATOM   3541  C  CZ  . PHE A 1 463 ? 221.820 191.236 191.801 1.00 60.10  ? 463 PHE A CZ  1 
ATOM   3542  N  N   . VAL A 1 464 ? 214.764 191.806 192.702 1.00 40.36  ? 464 VAL A N   1 
ATOM   3543  C  CA  . VAL A 1 464 ? 213.347 191.936 192.397 1.00 43.09  ? 464 VAL A CA  1 
ATOM   3544  C  C   . VAL A 1 464 ? 213.177 193.016 191.339 1.00 50.15  ? 464 VAL A C   1 
ATOM   3545  O  O   . VAL A 1 464 ? 213.789 194.085 191.434 1.00 56.69  ? 464 VAL A O   1 
ATOM   3546  C  CB  . VAL A 1 464 ? 212.525 192.287 193.648 1.00 47.81  ? 464 VAL A CB  1 
ATOM   3547  C  CG1 . VAL A 1 464 ? 211.191 192.878 193.251 1.00 47.95  ? 464 VAL A CG1 1 
ATOM   3548  C  CG2 . VAL A 1 464 ? 212.331 191.064 194.511 1.00 52.33  ? 464 VAL A CG2 1 
ATOM   3549  N  N   . LEU A 1 465 ? 212.356 192.736 190.330 1.00 52.35  ? 465 LEU A N   1 
ATOM   3550  C  CA  . LEU A 1 465 ? 211.960 193.729 189.339 1.00 49.52  ? 465 LEU A CA  1 
ATOM   3551  C  C   . LEU A 1 465 ? 210.451 193.904 189.394 1.00 48.37  ? 465 LEU A C   1 
ATOM   3552  O  O   . LEU A 1 465 ? 209.712 192.919 189.413 1.00 57.70  ? 465 LEU A O   1 
ATOM   3553  C  CB  . LEU A 1 465 ? 212.394 193.316 187.936 1.00 49.85  ? 465 LEU A CB  1 
ATOM   3554  C  CG  . LEU A 1 465 ? 212.461 194.454 186.921 1.00 51.99  ? 465 LEU A CG  1 
ATOM   3555  C  CD1 . LEU A 1 465 ? 213.697 194.318 186.073 1.00 48.06  ? 465 LEU A CD1 1 
ATOM   3556  C  CD2 . LEU A 1 465 ? 211.223 194.462 186.057 1.00 59.75  ? 465 LEU A CD2 1 
ATOM   3557  N  N   . VAL A 1 466 ? 209.993 195.144 189.424 1.00 45.40  ? 466 VAL A N   1 
ATOM   3558  C  CA  . VAL A 1 466 ? 208.576 195.448 189.535 1.00 53.42  ? 466 VAL A CA  1 
ATOM   3559  C  C   . VAL A 1 466 ? 208.153 196.213 188.294 1.00 63.96  ? 466 VAL A C   1 
ATOM   3560  O  O   . VAL A 1 466 ? 208.761 197.238 187.953 1.00 65.65  ? 466 VAL A O   1 
ATOM   3561  C  CB  . VAL A 1 466 ? 208.261 196.251 190.806 1.00 58.24  ? 466 VAL A CB  1 
ATOM   3562  C  CG1 . VAL A 1 466 ? 206.794 196.631 190.839 1.00 66.97  ? 466 VAL A CG1 1 
ATOM   3563  C  CG2 . VAL A 1 466 ? 208.626 195.450 192.034 1.00 55.93  ? 466 VAL A CG2 1 
ATOM   3564  N  N   . SER A 1 467 ? 207.115 195.714 187.623 1.00 69.64  ? 467 SER A N   1 
ATOM   3565  C  CA  . SER A 1 467 ? 206.595 196.353 186.424 1.00 71.28  ? 467 SER A CA  1 
ATOM   3566  C  C   . SER A 1 467 ? 205.079 196.404 186.490 1.00 75.56  ? 467 SER A C   1 
ATOM   3567  O  O   . SER A 1 467 ? 204.447 195.706 187.285 1.00 77.88  ? 467 SER A O   1 
ATOM   3568  C  CB  . SER A 1 467 ? 207.038 195.618 185.156 1.00 71.14  ? 467 SER A CB  1 
ATOM   3569  O  OG  . SER A 1 467 ? 208.419 195.810 184.915 1.00 69.52  ? 467 SER A OG  1 
ATOM   3570  N  N   . LEU A 1 468 ? 204.496 197.243 185.636 1.00 77.80  ? 468 LEU A N   1 
ATOM   3571  C  CA  . LEU A 1 468 ? 203.051 197.412 185.566 1.00 85.78  ? 468 LEU A CA  1 
ATOM   3572  C  C   . LEU A 1 468 ? 202.477 197.003 184.211 1.00 90.23  ? 468 LEU A C   1 
ATOM   3573  O  O   . LEU A 1 468 ? 201.503 197.604 183.749 1.00 93.00  ? 468 LEU A O   1 
ATOM   3574  C  CB  . LEU A 1 468 ? 202.669 198.857 185.886 1.00 86.98  ? 468 LEU A CB  1 
ATOM   3575  C  CG  . LEU A 1 468 ? 202.912 199.329 187.319 1.00 93.31  ? 468 LEU A CG  1 
ATOM   3576  C  CD1 . LEU A 1 468 ? 202.316 200.710 187.536 1.00 93.79  ? 468 LEU A CD1 1 
ATOM   3577  C  CD2 . LEU A 1 468 ? 202.339 198.334 188.314 1.00 96.77  ? 468 LEU A CD2 1 
ATOM   3578  N  N   . GLU A 1 469 ? 203.061 195.997 183.566 1.00 90.21  ? 469 GLU A N   1 
ATOM   3579  C  CA  . GLU A 1 469 ? 202.590 195.506 182.278 1.00 90.79  ? 469 GLU A CA  1 
ATOM   3580  C  C   . GLU A 1 469 ? 201.964 194.128 182.469 1.00 90.79  ? 469 GLU A C   1 
ATOM   3581  O  O   . GLU A 1 469 ? 202.623 193.208 182.964 1.00 90.02  ? 469 GLU A O   1 
ATOM   3582  C  CB  . GLU A 1 469 ? 203.740 195.451 181.273 1.00 87.49  ? 469 GLU A CB  1 
ATOM   3583  C  CG  . GLU A 1 469 ? 204.384 196.804 181.021 1.00 90.01  ? 469 GLU A CG  1 
ATOM   3584  C  CD  . GLU A 1 469 ? 205.547 196.732 180.053 1.00 92.62  ? 469 GLU A CD  1 
ATOM   3585  O  OE1 . GLU A 1 469 ? 205.909 195.612 179.637 1.00 86.87  ? 469 GLU A OE1 1 
ATOM   3586  O  OE2 . GLU A 1 469 ? 206.100 197.797 179.704 1.00 95.69  ? 469 GLU A OE2 1 
ATOM   3587  N  N   . ASN A 1 470 ? 200.697 193.989 182.076 1.00 89.29  ? 470 ASN A N   1 
ATOM   3588  C  CA  . ASN A 1 470 ? 199.927 192.781 182.340 1.00 88.15  ? 470 ASN A CA  1 
ATOM   3589  C  C   . ASN A 1 470 ? 199.781 191.875 181.127 1.00 83.30  ? 470 ASN A C   1 
ATOM   3590  O  O   . ASN A 1 470 ? 199.355 190.727 181.278 1.00 81.55  ? 470 ASN A O   1 
ATOM   3591  C  CB  . ASN A 1 470 ? 198.542 193.153 182.870 1.00 89.49  ? 470 ASN A CB  1 
ATOM   3592  C  CG  . ASN A 1 470 ? 198.584 194.328 183.819 1.00 93.11  ? 470 ASN A CG  1 
ATOM   3593  O  OD1 . ASN A 1 470 ? 199.626 194.635 184.396 1.00 93.69  ? 470 ASN A OD1 1 
ATOM   3594  N  ND2 . ASN A 1 470 ? 197.450 194.996 183.987 1.00 97.97  ? 470 ASN A ND2 1 
ATOM   3595  N  N   . ASP A 1 471 ? 200.120 192.348 179.937 1.00 81.59  ? 471 ASP A N   1 
ATOM   3596  C  CA  . ASP A 1 471 ? 200.033 191.532 178.737 1.00 81.70  ? 471 ASP A CA  1 
ATOM   3597  C  C   . ASP A 1 471 ? 201.199 190.555 178.703 1.00 74.67  ? 471 ASP A C   1 
ATOM   3598  O  O   . ASP A 1 471 ? 202.351 190.954 178.891 1.00 77.19  ? 471 ASP A O   1 
ATOM   3599  C  CB  . ASP A 1 471 ? 200.043 192.415 177.491 1.00 83.92  ? 471 ASP A CB  1 
ATOM   3600  C  CG  . ASP A 1 471 ? 199.283 193.711 177.692 1.00 93.86  ? 471 ASP A CG  1 
ATOM   3601  O  OD1 . ASP A 1 471 ? 198.194 193.675 178.303 1.00 98.97  ? 471 ASP A OD1 1 
ATOM   3602  O  OD2 . ASP A 1 471 ? 199.774 194.767 177.241 1.00 95.19  ? 471 ASP A OD2 1 
ATOM   3603  N  N   . VAL A 1 472 ? 200.900 189.275 178.463 1.00 67.41  ? 472 VAL A N   1 
ATOM   3604  C  CA  . VAL A 1 472 ? 201.956 188.266 178.426 1.00 64.59  ? 472 VAL A CA  1 
ATOM   3605  C  C   . VAL A 1 472 ? 202.920 188.541 177.286 1.00 64.14  ? 472 VAL A C   1 
ATOM   3606  O  O   . VAL A 1 472 ? 204.096 188.159 177.351 1.00 66.12  ? 472 VAL A O   1 
ATOM   3607  C  CB  . VAL A 1 472 ? 201.354 186.851 178.328 1.00 67.60  ? 472 VAL A CB  1 
ATOM   3608  C  CG1 . VAL A 1 472 ? 200.595 186.680 177.020 1.00 74.97  ? 472 VAL A CG1 1 
ATOM   3609  C  CG2 . VAL A 1 472 ? 202.445 185.795 178.465 1.00 62.94  ? 472 VAL A CG2 1 
ATOM   3610  N  N   . SER A 1 473 ? 202.454 189.223 176.240 1.00 63.53  ? 473 SER A N   1 
ATOM   3611  C  CA  . SER A 1 473 ? 203.334 189.547 175.124 1.00 68.31  ? 473 SER A CA  1 
ATOM   3612  C  C   . SER A 1 473 ? 204.490 190.430 175.563 1.00 69.28  ? 473 SER A C   1 
ATOM   3613  O  O   . SER A 1 473 ? 205.618 190.254 175.091 1.00 70.20  ? 473 SER A O   1 
ATOM   3614  C  CB  . SER A 1 473 ? 202.541 190.231 174.013 1.00 74.86  ? 473 SER A CB  1 
ATOM   3615  O  OG  . SER A 1 473 ? 201.662 191.205 174.546 1.00 80.49  ? 473 SER A OG  1 
ATOM   3616  N  N   . ASN A 1 474 ? 204.236 191.384 176.453 1.00 66.06  ? 474 ASN A N   1 
ATOM   3617  C  CA  . ASN A 1 474 ? 205.308 192.206 176.995 1.00 64.11  ? 474 ASN A CA  1 
ATOM   3618  C  C   . ASN A 1 474 ? 206.111 191.490 178.068 1.00 59.86  ? 474 ASN A C   1 
ATOM   3619  O  O   . ASN A 1 474 ? 207.323 191.706 178.174 1.00 62.88  ? 474 ASN A O   1 
ATOM   3620  C  CB  . ASN A 1 474 ? 204.729 193.494 177.573 1.00 71.33  ? 474 ASN A CB  1 
ATOM   3621  C  CG  . ASN A 1 474 ? 203.643 194.071 176.708 1.00 77.42  ? 474 ASN A CG  1 
ATOM   3622  O  OD1 . ASN A 1 474 ? 203.571 193.787 175.513 1.00 78.60  ? 474 ASN A OD1 1 
ATOM   3623  N  ND2 . ASN A 1 474 ? 202.786 194.890 177.303 1.00 82.07  ? 474 ASN A ND2 1 
ATOM   3624  N  N   . ILE A 1 475 ? 205.454 190.657 178.872 1.00 57.39  ? 475 ILE A N   1 
ATOM   3625  C  CA  . ILE A 1 475 ? 206.133 189.980 179.967 1.00 50.42  ? 475 ILE A CA  1 
ATOM   3626  C  C   . ILE A 1 475 ? 207.188 189.030 179.427 1.00 51.15  ? 475 ILE A C   1 
ATOM   3627  O  O   . ILE A 1 475 ? 208.312 188.967 179.944 1.00 54.75  ? 475 ILE A O   1 
ATOM   3628  C  CB  . ILE A 1 475 ? 205.106 189.269 180.866 1.00 47.55  ? 475 ILE A CB  1 
ATOM   3629  C  CG1 . ILE A 1 475 ? 204.293 190.308 181.623 1.00 53.14  ? 475 ILE A CG1 1 
ATOM   3630  C  CG2 . ILE A 1 475 ? 205.780 188.356 181.844 1.00 48.58  ? 475 ILE A CG2 1 
ATOM   3631  C  CD1 . ILE A 1 475 ? 203.298 189.719 182.572 1.00 61.34  ? 475 ILE A CD1 1 
ATOM   3632  N  N   . THR A 1 476 ? 206.857 188.283 178.376 1.00 50.33  ? 476 THR A N   1 
ATOM   3633  C  CA  . THR A 1 476 ? 207.844 187.366 177.823 1.00 50.50  ? 476 THR A CA  1 
ATOM   3634  C  C   . THR A 1 476 ? 209.019 188.117 177.216 1.00 54.85  ? 476 THR A C   1 
ATOM   3635  O  O   . THR A 1 476 ? 210.163 187.666 177.314 1.00 59.87  ? 476 THR A O   1 
ATOM   3636  C  CB  . THR A 1 476 ? 207.212 186.440 176.790 1.00 52.40  ? 476 THR A CB  1 
ATOM   3637  O  OG1 . THR A 1 476 ? 208.218 185.575 176.254 1.00 51.50  ? 476 THR A OG1 1 
ATOM   3638  C  CG2 . THR A 1 476 ? 206.594 187.232 175.663 1.00 60.60  ? 476 THR A CG2 1 
ATOM   3639  N  N   . GLN A 1 477 ? 208.766 189.271 176.600 1.00 54.01  ? 477 GLN A N   1 
ATOM   3640  C  CA  . GLN A 1 477 ? 209.859 190.059 176.042 1.00 59.04  ? 477 GLN A CA  1 
ATOM   3641  C  C   . GLN A 1 477 ? 210.770 190.589 177.139 1.00 61.73  ? 477 GLN A C   1 
ATOM   3642  O  O   . GLN A 1 477 ? 212.001 190.561 177.000 1.00 63.23  ? 477 GLN A O   1 
ATOM   3643  C  CB  . GLN A 1 477 ? 209.300 191.209 175.206 1.00 63.76  ? 477 GLN A CB  1 
ATOM   3644  C  CG  . GLN A 1 477 ? 210.343 192.004 174.433 1.00 69.94  ? 477 GLN A CG  1 
ATOM   3645  C  CD  . GLN A 1 477 ? 211.188 191.140 173.513 1.00 75.94  ? 477 GLN A CD  1 
ATOM   3646  O  OE1 . GLN A 1 477 ? 212.122 190.468 173.950 1.00 69.36  ? 477 GLN A OE1 1 
ATOM   3647  N  NE2 . GLN A 1 477 ? 210.856 191.152 172.227 1.00 80.18  ? 477 GLN A NE2 1 
ATOM   3648  N  N   . ILE A 1 478 ? 210.184 191.081 178.234 1.00 59.90  ? 478 ILE A N   1 
ATOM   3649  C  CA  . ILE A 1 478 ? 210.986 191.550 179.362 1.00 51.90  ? 478 ILE A CA  1 
ATOM   3650  C  C   . ILE A 1 478 ? 211.845 190.418 179.891 1.00 49.93  ? 478 ILE A C   1 
ATOM   3651  O  O   . ILE A 1 478 ? 213.046 190.583 180.134 1.00 56.17  ? 478 ILE A O   1 
ATOM   3652  C  CB  . ILE A 1 478 ? 210.086 192.113 180.474 1.00 49.86  ? 478 ILE A CB  1 
ATOM   3653  C  CG1 . ILE A 1 478 ? 209.435 193.418 180.048 1.00 49.85  ? 478 ILE A CG1 1 
ATOM   3654  C  CG2 . ILE A 1 478 ? 210.885 192.345 181.723 1.00 51.20  ? 478 ILE A CG2 1 
ATOM   3655  C  CD1 . ILE A 1 478 ? 208.593 194.023 181.129 1.00 50.86  ? 478 ILE A CD1 1 
ATOM   3656  N  N   . ALA A 1 479 ? 211.238 189.251 180.085 1.00 45.85  ? 479 ALA A N   1 
ATOM   3657  C  CA  . ALA A 1 479 ? 211.984 188.124 180.619 1.00 48.02  ? 479 ALA A CA  1 
ATOM   3658  C  C   . ALA A 1 479 ? 213.101 187.719 179.675 1.00 50.41  ? 479 ALA A C   1 
ATOM   3659  O  O   . ALA A 1 479 ? 214.195 187.357 180.115 1.00 53.46  ? 479 ALA A O   1 
ATOM   3660  C  CB  . ALA A 1 479 ? 211.046 186.951 180.883 1.00 55.55  ? 479 ALA A CB  1 
ATOM   3661  N  N   . ASP A 1 480 ? 212.848 187.783 178.368 1.00 53.02  ? 480 ASP A N   1 
ATOM   3662  C  CA  . ASP A 1 480 ? 213.859 187.390 177.396 1.00 59.38  ? 480 ASP A CA  1 
ATOM   3663  C  C   . ASP A 1 480 ? 215.041 188.352 177.388 1.00 63.73  ? 480 ASP A C   1 
ATOM   3664  O  O   . ASP A 1 480 ? 216.196 187.916 177.335 1.00 67.97  ? 480 ASP A O   1 
ATOM   3665  C  CB  . ASP A 1 480 ? 213.235 187.286 176.008 1.00 63.22  ? 480 ASP A CB  1 
ATOM   3666  C  CG  . ASP A 1 480 ? 212.951 185.855 175.608 1.00 66.53  ? 480 ASP A CG  1 
ATOM   3667  O  OD1 . ASP A 1 480 ? 213.437 184.939 176.303 1.00 61.16  ? 480 ASP A OD1 1 
ATOM   3668  O  OD2 . ASP A 1 480 ? 212.242 185.645 174.602 1.00 69.89  ? 480 ASP A OD2 1 
ATOM   3669  N  N   . GLU A 1 481 ? 214.787 189.662 177.436 1.00 63.21  ? 481 GLU A N   1 
ATOM   3670  C  CA  . GLU A 1 481 ? 215.920 190.585 177.466 1.00 60.81  ? 481 GLU A CA  1 
ATOM   3671  C  C   . GLU A 1 481 ? 216.692 190.458 178.774 1.00 60.31  ? 481 GLU A C   1 
ATOM   3672  O  O   . GLU A 1 481 ? 217.924 190.553 178.784 1.00 62.74  ? 481 GLU A O   1 
ATOM   3673  C  CB  . GLU A 1 481 ? 215.472 192.031 177.249 1.00 64.83  ? 481 GLU A CB  1 
ATOM   3674  C  CG  . GLU A 1 481 ? 214.207 192.443 177.964 1.00 66.22  ? 481 GLU A CG  1 
ATOM   3675  C  CD  . GLU A 1 481 ? 213.892 193.915 177.784 1.00 72.06  ? 481 GLU A CD  1 
ATOM   3676  O  OE1 . GLU A 1 481 ? 213.117 194.463 178.597 1.00 74.10  ? 481 GLU A OE1 1 
ATOM   3677  O  OE2 . GLU A 1 481 ? 214.424 194.526 176.834 1.00 71.53  ? 481 GLU A OE2 1 
ATOM   3678  N  N   . LEU A 1 482 ? 215.988 190.234 179.889 1.00 59.83  ? 482 LEU A N   1 
ATOM   3679  C  CA  . LEU A 1 482 ? 216.682 190.013 181.153 1.00 58.45  ? 482 LEU A CA  1 
ATOM   3680  C  C   . LEU A 1 482 ? 217.560 188.773 181.085 1.00 67.38  ? 482 LEU A C   1 
ATOM   3681  O  O   . LEU A 1 482 ? 218.689 188.775 181.587 1.00 72.83  ? 482 LEU A O   1 
ATOM   3682  C  CB  . LEU A 1 482 ? 215.683 189.875 182.296 1.00 51.70  ? 482 LEU A CB  1 
ATOM   3683  C  CG  . LEU A 1 482 ? 215.142 191.130 182.963 1.00 50.13  ? 482 LEU A CG  1 
ATOM   3684  C  CD1 . LEU A 1 482 ? 214.262 190.730 184.112 1.00 49.06  ? 482 LEU A CD1 1 
ATOM   3685  C  CD2 . LEU A 1 482 ? 216.269 192.019 183.438 1.00 57.40  ? 482 LEU A CD2 1 
ATOM   3686  N  N   . ARG A 1 483 ? 217.054 187.697 180.479 1.00 66.50  ? 483 ARG A N   1 
ATOM   3687  C  CA  . ARG A 1 483 ? 217.860 186.492 180.323 1.00 64.55  ? 483 ARG A CA  1 
ATOM   3688  C  C   . ARG A 1 483 ? 219.055 186.750 179.421 1.00 65.98  ? 483 ARG A C   1 
ATOM   3689  O  O   . ARG A 1 483 ? 220.145 186.220 179.659 1.00 67.84  ? 483 ARG A O   1 
ATOM   3690  C  CB  . ARG A 1 483 ? 217.005 185.357 179.765 1.00 66.55  ? 483 ARG A CB  1 
ATOM   3691  C  CG  . ARG A 1 483 ? 217.724 184.021 179.683 1.00 72.11  ? 483 ARG A CG  1 
ATOM   3692  C  CD  . ARG A 1 483 ? 216.948 183.036 178.827 1.00 73.64  ? 483 ARG A CD  1 
ATOM   3693  N  NE  . ARG A 1 483 ? 217.586 181.728 178.790 1.00 74.58  ? 483 ARG A NE  1 
ATOM   3694  C  CZ  . ARG A 1 483 ? 217.616 180.940 177.725 1.00 73.54  ? 483 ARG A CZ  1 
ATOM   3695  N  NH1 . ARG A 1 483 ? 217.051 181.298 176.584 1.00 72.20  ? 483 ARG A NH1 1 
ATOM   3696  N  NH2 . ARG A 1 483 ? 218.231 179.763 177.806 1.00 75.89  ? 483 ARG A NH2 1 
ATOM   3697  N  N   . ASN A 1 484 ? 218.869 187.558 178.381 1.00 65.48  ? 484 ASN A N   1 
ATOM   3698  C  CA  . ASN A 1 484 ? 219.945 187.863 177.451 1.00 71.58  ? 484 ASN A CA  1 
ATOM   3699  C  C   . ASN A 1 484 ? 220.938 188.878 178.002 1.00 78.48  ? 484 ASN A C   1 
ATOM   3700  O  O   . ASN A 1 484 ? 221.974 189.111 177.370 1.00 83.62  ? 484 ASN A O   1 
ATOM   3701  C  CB  . ASN A 1 484 ? 219.361 188.373 176.134 1.00 72.69  ? 484 ASN A CB  1 
ATOM   3702  C  CG  . ASN A 1 484 ? 218.681 187.276 175.338 1.00 76.44  ? 484 ASN A CG  1 
ATOM   3703  O  OD1 . ASN A 1 484 ? 218.872 186.090 175.605 1.00 74.21  ? 484 ASN A OD1 1 
ATOM   3704  N  ND2 . ASN A 1 484 ? 217.879 187.668 174.354 1.00 74.51  ? 484 ASN A ND2 1 
ATOM   3705  N  N   . VAL A 1 485 ? 220.629 189.505 179.140 1.00 78.32  ? 485 VAL A N   1 
ATOM   3706  C  CA  . VAL A 1 485 ? 221.589 190.389 179.803 1.00 76.20  ? 485 VAL A CA  1 
ATOM   3707  C  C   . VAL A 1 485 ? 222.929 189.690 179.976 1.00 77.25  ? 485 VAL A C   1 
ATOM   3708  O  O   . VAL A 1 485 ? 223.993 190.302 179.825 1.00 78.10  ? 485 VAL A O   1 
ATOM   3709  C  CB  . VAL A 1 485 ? 221.025 190.865 181.155 1.00 74.20  ? 485 VAL A CB  1 
ATOM   3710  C  CG1 . VAL A 1 485 ? 222.146 191.202 182.123 1.00 79.51  ? 485 VAL A CG1 1 
ATOM   3711  C  CG2 . VAL A 1 485 ? 220.111 192.057 180.959 1.00 73.87  ? 485 VAL A CG2 1 
ATOM   3712  N  N   . VAL A 1 486 ? 222.903 188.395 180.260 1.00 78.63  ? 486 VAL A N   1 
ATOM   3713  C  CA  . VAL A 1 486 ? 224.116 187.626 180.476 1.00 83.58  ? 486 VAL A CA  1 
ATOM   3714  C  C   . VAL A 1 486 ? 224.531 186.865 179.215 1.00 88.40  ? 486 VAL A C   1 
ATOM   3715  O  O   . VAL A 1 486 ? 225.214 185.847 179.302 1.00 91.40  ? 486 VAL A O   1 
ATOM   3716  C  CB  . VAL A 1 486 ? 223.976 186.680 181.677 1.00 82.31  ? 486 VAL A CB  1 
ATOM   3717  C  CG1 . VAL A 1 486 ? 223.624 187.467 182.921 1.00 78.15  ? 486 VAL A CG1 1 
ATOM   3718  C  CG2 . VAL A 1 486 ? 222.923 185.623 181.403 1.00 79.72  ? 486 VAL A CG2 1 
ATOM   3719  N  N   . SER A 1 487 ? 224.120 187.343 178.039 1.00 88.91  ? 487 SER A N   1 
ATOM   3720  C  CA  . SER A 1 487 ? 224.563 186.716 176.799 1.00 93.21  ? 487 SER A CA  1 
ATOM   3721  C  C   . SER A 1 487 ? 226.077 186.778 176.666 1.00 100.64 ? 487 SER A C   1 
ATOM   3722  O  O   . SER A 1 487 ? 226.709 185.815 176.216 1.00 104.25 ? 487 SER A O   1 
ATOM   3723  C  CB  . SER A 1 487 ? 223.892 187.384 175.599 1.00 94.44  ? 487 SER A CB  1 
ATOM   3724  O  OG  . SER A 1 487 ? 224.078 188.789 175.628 1.00 92.85  ? 487 SER A OG  1 
ATOM   3725  N  N   . LYS A 1 488 ? 226.679 187.899 177.052 1.00 98.81  ? 488 LYS A N   1 
ATOM   3726  C  CA  . LYS A 1 488 ? 228.129 188.008 177.076 1.00 100.49 ? 488 LYS A CA  1 
ATOM   3727  C  C   . LYS A 1 488 ? 228.637 187.596 178.449 1.00 103.07 ? 488 LYS A C   1 
ATOM   3728  O  O   . LYS A 1 488 ? 228.278 188.239 179.445 1.00 102.72 ? 488 LYS A O   1 
ATOM   3729  C  CB  . LYS A 1 488 ? 228.570 189.425 176.761 1.00 100.31 ? 488 LYS A CB  1 
ATOM   3730  C  CG  . LYS A 1 488 ? 228.286 189.856 175.333 1.00 105.10 ? 488 LYS A CG  1 
ATOM   3731  C  CD  . LYS A 1 488 ? 228.863 191.233 175.045 1.00 112.11 ? 488 LYS A CD  1 
ATOM   3732  C  CE  . LYS A 1 488 ? 228.607 191.651 173.605 1.00 112.25 ? 488 LYS A CE  1 
ATOM   3733  N  NZ  . LYS A 1 488 ? 229.175 192.995 173.305 1.00 111.71 ? 488 LYS A NZ  1 
ATOM   3734  N  N   . PRO A 1 489 ? 229.439 186.539 178.558 1.00 104.79 ? 489 PRO A N   1 
ATOM   3735  C  CA  . PRO A 1 489 ? 229.938 186.129 179.874 1.00 107.61 ? 489 PRO A CA  1 
ATOM   3736  C  C   . PRO A 1 489 ? 230.766 187.229 180.517 1.00 110.26 ? 489 PRO A C   1 
ATOM   3737  O  O   . PRO A 1 489 ? 231.476 187.979 179.844 1.00 109.33 ? 489 PRO A O   1 
ATOM   3738  C  CB  . PRO A 1 489 ? 230.790 184.893 179.565 1.00 110.85 ? 489 PRO A CB  1 
ATOM   3739  C  CG  . PRO A 1 489 ? 230.288 184.402 178.244 1.00 106.47 ? 489 PRO A CG  1 
ATOM   3740  C  CD  . PRO A 1 489 ? 229.877 185.628 177.489 1.00 104.01 ? 489 PRO A CD  1 
ATOM   3741  N  N   . ILE A 1 490 ? 230.661 187.318 181.844 1.00 111.68 ? 490 ILE A N   1 
ATOM   3742  C  CA  . ILE A 1 490 ? 231.323 188.388 182.576 1.00 115.09 ? 490 ILE A CA  1 
ATOM   3743  C  C   . ILE A 1 490 ? 232.833 188.243 182.459 1.00 123.26 ? 490 ILE A C   1 
ATOM   3744  O  O   . ILE A 1 490 ? 233.388 187.147 182.607 1.00 124.10 ? 490 ILE A O   1 
ATOM   3745  C  CB  . ILE A 1 490 ? 230.871 188.381 184.045 1.00 113.49 ? 490 ILE A CB  1 
ATOM   3746  C  CG1 . ILE A 1 490 ? 229.393 188.753 184.143 1.00 105.01 ? 490 ILE A CG1 1 
ATOM   3747  C  CG2 . ILE A 1 490 ? 231.704 189.346 184.869 1.00 114.93 ? 490 ILE A CG2 1 
ATOM   3748  C  CD1 . ILE A 1 490 ? 228.812 188.551 185.520 1.00 100.51 ? 490 ILE A CD1 1 
ATOM   3749  N  N   . MET A 1 491 ? 233.502 189.360 182.181 1.00 128.50 ? 491 MET A N   1 
ATOM   3750  C  CA  . MET A 1 491 ? 234.948 189.408 182.009 1.00 132.94 ? 491 MET A CA  1 
ATOM   3751  C  C   . MET A 1 491 ? 235.581 189.916 183.299 1.00 133.56 ? 491 MET A C   1 
ATOM   3752  O  O   . MET A 1 491 ? 235.364 191.070 183.684 1.00 131.41 ? 491 MET A O   1 
ATOM   3753  C  CB  . MET A 1 491 ? 235.316 190.330 180.844 1.00 136.02 ? 491 MET A CB  1 
ATOM   3754  C  CG  . MET A 1 491 ? 236.715 190.172 180.224 1.00 138.76 ? 491 MET A CG  1 
ATOM   3755  S  SD  . MET A 1 491 ? 237.661 188.633 180.363 1.00 143.40 ? 491 MET A SD  1 
ATOM   3756  C  CE  . MET A 1 491 ? 236.487 187.375 179.854 1.00 133.02 ? 491 MET A CE  1 
ATOM   3757  N  N   . ILE A 1 492 ? 236.361 189.066 183.966 1.00 136.63 ? 492 ILE A N   1 
ATOM   3758  C  CA  . ILE A 1 492 ? 237.058 189.442 185.193 1.00 140.96 ? 492 ILE A CA  1 
ATOM   3759  C  C   . ILE A 1 492 ? 238.502 188.974 185.076 1.00 142.90 ? 492 ILE A C   1 
ATOM   3760  O  O   . ILE A 1 492 ? 238.767 187.765 185.064 1.00 141.93 ? 492 ILE A O   1 
ATOM   3761  C  CB  . ILE A 1 492 ? 236.398 188.853 186.447 1.00 139.95 ? 492 ILE A CB  1 
ATOM   3762  C  CG1 . ILE A 1 492 ? 234.944 189.315 186.563 1.00 134.26 ? 492 ILE A CG1 1 
ATOM   3763  C  CG2 . ILE A 1 492 ? 237.171 189.260 187.690 1.00 137.79 ? 492 ILE A CG2 1 
ATOM   3764  C  CD1 . ILE A 1 492 ? 234.142 188.553 187.595 1.00 126.77 ? 492 ILE A CD1 1 
ATOM   3765  N  N   . ASP A 1 493 ? 239.433 189.927 185.005 1.00 144.49 ? 493 ASP A N   1 
ATOM   3766  C  CA  . ASP A 1 493 ? 240.869 189.643 184.973 1.00 144.61 ? 493 ASP A CA  1 
ATOM   3767  C  C   . ASP A 1 493 ? 241.215 188.654 183.863 1.00 141.65 ? 493 ASP A C   1 
ATOM   3768  O  O   . ASP A 1 493 ? 241.870 187.633 184.085 1.00 139.22 ? 493 ASP A O   1 
ATOM   3769  C  CB  . ASP A 1 493 ? 241.353 189.134 186.332 1.00 146.24 ? 493 ASP A CB  1 
ATOM   3770  C  CG  . ASP A 1 493 ? 241.232 190.180 187.423 1.00 145.04 ? 493 ASP A CG  1 
ATOM   3771  O  OD1 . ASP A 1 493 ? 240.984 191.359 187.094 1.00 145.38 ? 493 ASP A OD1 1 
ATOM   3772  O  OD2 . ASP A 1 493 ? 241.387 189.823 188.610 1.00 142.84 ? 493 ASP A OD2 1 
ATOM   3773  N  N   . ASP A 1 494 ? 240.754 188.967 182.650 1.00 139.66 ? 494 ASP A N   1 
ATOM   3774  C  CA  . ASP A 1 494 ? 240.959 188.118 181.477 1.00 140.01 ? 494 ASP A CA  1 
ATOM   3775  C  C   . ASP A 1 494 ? 240.414 186.710 181.700 1.00 139.34 ? 494 ASP A C   1 
ATOM   3776  O  O   . ASP A 1 494 ? 240.958 185.732 181.182 1.00 137.86 ? 494 ASP A O   1 
ATOM   3777  C  CB  . ASP A 1 494 ? 242.437 188.063 181.077 1.00 142.19 ? 494 ASP A CB  1 
ATOM   3778  C  CG  . ASP A 1 494 ? 242.995 189.426 180.720 1.00 142.12 ? 494 ASP A CG  1 
ATOM   3779  O  OD1 . ASP A 1 494 ? 242.193 190.350 180.468 1.00 141.95 ? 494 ASP A OD1 1 
ATOM   3780  O  OD2 . ASP A 1 494 ? 244.235 189.573 180.692 1.00 140.44 ? 494 ASP A OD2 1 
ATOM   3781  N  N   . LYS A 1 495 ? 239.336 186.599 182.473 1.00 139.39 ? 495 LYS A N   1 
ATOM   3782  C  CA  . LYS A 1 495 ? 238.729 185.316 182.792 1.00 134.95 ? 495 LYS A CA  1 
ATOM   3783  C  C   . LYS A 1 495 ? 237.230 185.397 182.529 1.00 131.36 ? 495 LYS A C   1 
ATOM   3784  O  O   . LYS A 1 495 ? 236.560 186.315 183.033 1.00 131.66 ? 495 LYS A O   1 
ATOM   3785  C  CB  . LYS A 1 495 ? 238.997 184.925 184.251 1.00 134.79 ? 495 LYS A CB  1 
ATOM   3786  C  CG  . LYS A 1 495 ? 240.466 184.734 184.585 1.00 134.36 ? 495 LYS A CG  1 
ATOM   3787  C  CD  . LYS A 1 495 ? 240.639 183.878 185.829 1.00 132.78 ? 495 LYS A CD  1 
ATOM   3788  C  CE  . LYS A 1 495 ? 242.099 183.795 186.246 1.00 132.35 ? 495 LYS A CE  1 
ATOM   3789  N  NZ  . LYS A 1 495 ? 242.280 182.978 187.477 1.00 130.03 ? 495 LYS A NZ  1 
ATOM   3790  N  N   . PRO A 1 496 ? 236.674 184.485 181.741 1.00 129.85 ? 496 PRO A N   1 
ATOM   3791  C  CA  . PRO A 1 496 ? 235.228 184.490 181.511 1.00 128.20 ? 496 PRO A CA  1 
ATOM   3792  C  C   . PRO A 1 496 ? 234.478 183.831 182.654 1.00 125.29 ? 496 PRO A C   1 
ATOM   3793  O  O   . PRO A 1 496 ? 235.004 182.978 183.372 1.00 127.15 ? 496 PRO A O   1 
ATOM   3794  C  CB  . PRO A 1 496 ? 235.068 183.683 180.214 1.00 127.03 ? 496 PRO A CB  1 
ATOM   3795  C  CG  . PRO A 1 496 ? 236.473 183.421 179.708 1.00 129.41 ? 496 PRO A CG  1 
ATOM   3796  C  CD  . PRO A 1 496 ? 237.358 183.490 180.904 1.00 130.14 ? 496 PRO A CD  1 
ATOM   3797  N  N   . PHE A 1 497 ? 233.235 184.256 182.824 1.00 120.53 ? 497 PHE A N   1 
ATOM   3798  C  CA  . PHE A 1 497 ? 232.332 183.643 183.796 1.00 117.04 ? 497 PHE A CA  1 
ATOM   3799  C  C   . PHE A 1 497 ? 230.919 183.734 183.246 1.00 111.57 ? 497 PHE A C   1 
ATOM   3800  O  O   . PHE A 1 497 ? 230.305 184.812 183.253 1.00 111.70 ? 497 PHE A O   1 
ATOM   3801  C  CB  . PHE A 1 497 ? 232.439 184.308 185.165 1.00 123.12 ? 497 PHE A CB  1 
ATOM   3802  C  CG  . PHE A 1 497 ? 233.728 184.014 185.874 1.00 127.87 ? 497 PHE A CG  1 
ATOM   3803  C  CD1 . PHE A 1 497 ? 233.959 182.765 186.425 1.00 124.91 ? 497 PHE A CD1 1 
ATOM   3804  C  CD2 . PHE A 1 497 ? 234.714 184.980 185.974 1.00 129.16 ? 497 PHE A CD2 1 
ATOM   3805  C  CE1 . PHE A 1 497 ? 235.145 182.488 187.072 1.00 124.75 ? 497 PHE A CE1 1 
ATOM   3806  C  CE2 . PHE A 1 497 ? 235.903 184.709 186.621 1.00 131.38 ? 497 PHE A CE2 1 
ATOM   3807  C  CZ  . PHE A 1 497 ? 236.119 183.462 187.171 1.00 129.74 ? 497 PHE A CZ  1 
ATOM   3808  N  N   . PRO A 1 498 ? 230.372 182.634 182.752 1.00 109.44 ? 498 PRO A N   1 
ATOM   3809  C  CA  . PRO A 1 498 ? 229.021 182.643 182.157 1.00 109.79 ? 498 PRO A CA  1 
ATOM   3810  C  C   . PRO A 1 498 ? 227.927 182.422 183.197 1.00 102.88 ? 498 PRO A C   1 
ATOM   3811  O  O   . PRO A 1 498 ? 227.316 181.353 183.300 1.00 103.32 ? 498 PRO A O   1 
ATOM   3812  C  CB  . PRO A 1 498 ? 229.107 181.502 181.144 1.00 114.74 ? 498 PRO A CB  1 
ATOM   3813  C  CG  . PRO A 1 498 ? 230.055 180.524 181.780 1.00 115.41 ? 498 PRO A CG  1 
ATOM   3814  C  CD  . PRO A 1 498 ? 231.010 181.311 182.651 1.00 112.54 ? 498 PRO A CD  1 
ATOM   3815  N  N   . LEU A 1 499 ? 227.670 183.449 183.999 1.00 96.61  ? 499 LEU A N   1 
ATOM   3816  C  CA  . LEU A 1 499 ? 226.638 183.349 185.018 1.00 91.22  ? 499 LEU A CA  1 
ATOM   3817  C  C   . LEU A 1 499 ? 225.263 183.244 184.374 1.00 92.16  ? 499 LEU A C   1 
ATOM   3818  O  O   . LEU A 1 499 ? 224.973 183.905 183.373 1.00 92.08  ? 499 LEU A O   1 
ATOM   3819  C  CB  . LEU A 1 499 ? 226.695 184.558 185.947 1.00 95.98  ? 499 LEU A CB  1 
ATOM   3820  C  CG  . LEU A 1 499 ? 228.025 184.802 186.662 1.00 104.12 ? 499 LEU A CG  1 
ATOM   3821  C  CD1 . LEU A 1 499 ? 227.850 185.807 187.789 1.00 103.04 ? 499 LEU A CD1 1 
ATOM   3822  C  CD2 . LEU A 1 499 ? 228.602 183.498 187.192 1.00 107.84 ? 499 LEU A CD2 1 
ATOM   3823  N  N   . THR A 1 500 ? 224.411 182.408 184.956 1.00 94.16  ? 500 THR A N   1 
ATOM   3824  C  CA  . THR A 1 500 ? 223.065 182.179 184.459 1.00 86.15  ? 500 THR A CA  1 
ATOM   3825  C  C   . THR A 1 500 ? 222.048 182.830 185.384 1.00 81.67  ? 500 THR A C   1 
ATOM   3826  O  O   . THR A 1 500 ? 222.375 183.288 186.482 1.00 84.47  ? 500 THR A O   1 
ATOM   3827  C  CB  . THR A 1 500 ? 222.768 180.682 184.339 1.00 85.96  ? 500 THR A CB  1 
ATOM   3828  O  OG1 . THR A 1 500 ? 222.891 180.067 185.626 1.00 89.38  ? 500 THR A OG1 1 
ATOM   3829  C  CG2 . THR A 1 500 ? 223.740 180.023 183.373 1.00 84.68  ? 500 THR A CG2 1 
ATOM   3830  N  N   . LEU A 1 501 ? 220.802 182.860 184.928 1.00 74.39  ? 501 LEU A N   1 
ATOM   3831  C  CA  . LEU A 1 501 ? 219.717 183.515 185.637 1.00 69.12  ? 501 LEU A CA  1 
ATOM   3832  C  C   . LEU A 1 501 ? 218.563 182.540 185.805 1.00 67.72  ? 501 LEU A C   1 
ATOM   3833  O  O   . LEU A 1 501 ? 218.297 181.724 184.917 1.00 73.37  ? 501 LEU A O   1 
ATOM   3834  C  CB  . LEU A 1 501 ? 219.243 184.741 184.872 1.00 66.50  ? 501 LEU A CB  1 
ATOM   3835  C  CG  . LEU A 1 501 ? 220.143 185.972 184.919 1.00 68.96  ? 501 LEU A CG  1 
ATOM   3836  C  CD1 . LEU A 1 501 ? 220.081 186.706 183.595 1.00 71.35  ? 501 LEU A CD1 1 
ATOM   3837  C  CD2 . LEU A 1 501 ? 219.775 186.888 186.035 1.00 67.15  ? 501 LEU A CD2 1 
ATOM   3838  N  N   . SER A 1 502 ? 217.877 182.622 186.936 1.00 65.03  ? 502 SER A N   1 
ATOM   3839  C  CA  . SER A 1 502 ? 216.650 181.873 187.157 1.00 66.55  ? 502 SER A CA  1 
ATOM   3840  C  C   . SER A 1 502 ? 215.584 182.818 187.688 1.00 58.78  ? 502 SER A C   1 
ATOM   3841  O  O   . SER A 1 502 ? 215.773 183.446 188.732 1.00 63.41  ? 502 SER A O   1 
ATOM   3842  C  CB  . SER A 1 502 ? 216.889 180.714 188.120 1.00 75.16  ? 502 SER A CB  1 
ATOM   3843  O  OG  . SER A 1 502 ? 218.176 180.161 187.921 1.00 79.14  ? 502 SER A OG  1 
ATOM   3844  N  N   . ILE A 1 503 ? 214.482 182.940 186.956 1.00 53.57  ? 503 ILE A N   1 
ATOM   3845  C  CA  . ILE A 1 503 ? 213.524 184.014 187.173 1.00 48.52  ? 503 ILE A CA  1 
ATOM   3846  C  C   . ILE A 1 503 ? 212.143 183.437 187.409 1.00 52.10  ? 503 ILE A C   1 
ATOM   3847  O  O   . ILE A 1 503 ? 211.690 182.564 186.661 1.00 59.66  ? 503 ILE A O   1 
ATOM   3848  C  CB  . ILE A 1 503 ? 213.477 184.990 185.987 1.00 46.63  ? 503 ILE A CB  1 
ATOM   3849  C  CG1 . ILE A 1 503 ? 214.881 185.299 185.488 1.00 48.79  ? 503 ILE A CG1 1 
ATOM   3850  C  CG2 . ILE A 1 503 ? 212.765 186.254 186.390 1.00 50.57  ? 503 ILE A CG2 1 
ATOM   3851  C  CD1 . ILE A 1 503 ? 214.931 186.450 184.528 1.00 49.17  ? 503 ILE A CD1 1 
ATOM   3852  N  N   . GLY A 1 504 ? 211.467 183.945 188.426 1.00 52.78  ? 504 GLY A N   1 
ATOM   3853  C  CA  . GLY A 1 504 ? 210.103 183.559 188.710 1.00 53.89  ? 504 GLY A CA  1 
ATOM   3854  C  C   . GLY A 1 504 ? 209.187 184.757 188.709 1.00 47.35  ? 504 GLY A C   1 
ATOM   3855  O  O   . GLY A 1 504 ? 209.412 185.712 189.451 1.00 49.91  ? 504 GLY A O   1 
ATOM   3856  N  N   . ILE A 1 505 ? 208.160 184.726 187.874 1.00 47.95  ? 505 ILE A N   1 
ATOM   3857  C  CA  . ILE A 1 505 ? 207.262 185.854 187.693 1.00 50.84  ? 505 ILE A CA  1 
ATOM   3858  C  C   . ILE A 1 505 ? 205.974 185.562 188.429 1.00 53.91  ? 505 ILE A C   1 
ATOM   3859  O  O   . ILE A 1 505 ? 205.465 184.438 188.388 1.00 67.44  ? 505 ILE A O   1 
ATOM   3860  C  CB  . ILE A 1 505 ? 206.991 186.137 186.205 1.00 58.09  ? 505 ILE A CB  1 
ATOM   3861  C  CG1 . ILE A 1 505 ? 208.293 186.516 185.505 1.00 60.48  ? 505 ILE A CG1 1 
ATOM   3862  C  CG2 . ILE A 1 505 ? 205.976 187.242 186.053 1.00 55.43  ? 505 ILE A CG2 1 
ATOM   3863  C  CD1 . ILE A 1 505 ? 208.772 185.505 184.509 1.00 54.46  ? 505 ILE A CD1 1 
ATOM   3864  N  N   . SER A 1 506 ? 205.468 186.560 189.127 1.00 49.82  ? 506 SER A N   1 
ATOM   3865  C  CA  . SER A 1 506 ? 204.181 186.466 189.786 1.00 61.76  ? 506 SER A CA  1 
ATOM   3866  C  C   . SER A 1 506 ? 203.340 187.664 189.392 1.00 70.58  ? 506 SER A C   1 
ATOM   3867  O  O   . SER A 1 506 ? 203.849 188.783 189.275 1.00 74.41  ? 506 SER A O   1 
ATOM   3868  C  CB  . SER A 1 506 ? 204.324 186.406 191.304 1.00 74.06  ? 506 SER A CB  1 
ATOM   3869  O  OG  . SER A 1 506 ? 203.107 186.751 191.941 1.00 83.68  ? 506 SER A OG  1 
ATOM   3870  N  N   . TYR A 1 507 ? 202.055 187.414 189.172 1.00 79.07  ? 507 TYR A N   1 
ATOM   3871  C  CA  . TYR A 1 507 ? 201.108 188.459 188.804 1.00 86.07  ? 507 TYR A CA  1 
ATOM   3872  C  C   . TYR A 1 507 ? 199.712 187.924 189.063 1.00 99.22  ? 507 TYR A C   1 
ATOM   3873  O  O   . TYR A 1 507 ? 199.292 186.961 188.415 1.00 103.87 ? 507 TYR A O   1 
ATOM   3874  C  CB  . TYR A 1 507 ? 201.277 188.855 187.340 1.00 87.39  ? 507 TYR A CB  1 
ATOM   3875  C  CG  . TYR A 1 507 ? 200.033 189.420 186.703 1.00 93.60  ? 507 TYR A CG  1 
ATOM   3876  C  CD1 . TYR A 1 507 ? 199.502 190.631 187.124 1.00 94.37  ? 507 TYR A CD1 1 
ATOM   3877  C  CD2 . TYR A 1 507 ? 199.394 188.747 185.675 1.00 97.38  ? 507 TYR A CD2 1 
ATOM   3878  C  CE1 . TYR A 1 507 ? 198.365 191.153 186.542 1.00 100.92 ? 507 TYR A CE1 1 
ATOM   3879  C  CE2 . TYR A 1 507 ? 198.255 189.259 185.086 1.00 96.14  ? 507 TYR A CE2 1 
ATOM   3880  C  CZ  . TYR A 1 507 ? 197.745 190.463 185.523 1.00 100.35 ? 507 TYR A CZ  1 
ATOM   3881  O  OH  . TYR A 1 507 ? 196.611 190.980 184.940 1.00 96.69  ? 507 TYR A OH  1 
ATOM   3882  N  N   . ASP A 1 508 ? 198.999 188.532 190.006 1.00 105.01 ? 508 ASP A N   1 
ATOM   3883  C  CA  . ASP A 1 508 ? 197.653 188.083 190.327 1.00 111.12 ? 508 ASP A CA  1 
ATOM   3884  C  C   . ASP A 1 508 ? 196.875 189.242 190.928 1.00 111.18 ? 508 ASP A C   1 
ATOM   3885  O  O   . ASP A 1 508 ? 197.411 190.003 191.737 1.00 108.87 ? 508 ASP A O   1 
ATOM   3886  C  CB  . ASP A 1 508 ? 197.675 186.891 191.289 1.00 111.22 ? 508 ASP A CB  1 
ATOM   3887  C  CG  . ASP A 1 508 ? 196.412 186.059 191.210 1.00 113.64 ? 508 ASP A CG  1 
ATOM   3888  O  OD1 . ASP A 1 508 ? 195.481 186.461 190.480 1.00 114.76 ? 508 ASP A OD1 1 
ATOM   3889  O  OD2 . ASP A 1 508 ? 196.351 185.001 191.871 1.00 111.29 ? 508 ASP A OD2 1 
ATOM   3890  N  N   . LEU A 1 509 ? 195.614 189.362 190.532 1.00 109.83 ? 509 LEU A N   1 
ATOM   3891  C  CA  . LEU A 1 509 ? 194.815 190.506 190.939 1.00 109.05 ? 509 LEU A CA  1 
ATOM   3892  C  C   . LEU A 1 509 ? 194.277 190.308 192.350 1.00 111.03 ? 509 LEU A C   1 
ATOM   3893  O  O   . LEU A 1 509 ? 193.691 189.267 192.663 1.00 110.84 ? 509 LEU A O   1 
ATOM   3894  C  CB  . LEU A 1 509 ? 193.663 190.715 189.960 1.00 109.12 ? 509 LEU A CB  1 
ATOM   3895  C  CG  . LEU A 1 509 ? 193.977 190.477 188.483 1.00 108.37 ? 509 LEU A CG  1 
ATOM   3896  C  CD1 . LEU A 1 509 ? 192.717 190.608 187.640 1.00 112.39 ? 509 LEU A CD1 1 
ATOM   3897  C  CD2 . LEU A 1 509 ? 195.046 191.440 188.000 1.00 107.04 ? 509 LEU A CD2 1 
ATOM   3898  N  N   . GLY A 1 510 ? 194.481 191.310 193.203 1.00 111.46 ? 510 GLY A N   1 
ATOM   3899  C  CA  . GLY A 1 510 ? 193.917 191.328 194.533 1.00 111.62 ? 510 GLY A CA  1 
ATOM   3900  C  C   . GLY A 1 510 ? 194.762 190.673 195.605 1.00 114.40 ? 510 GLY A C   1 
ATOM   3901  O  O   . GLY A 1 510 ? 194.521 190.914 196.793 1.00 114.63 ? 510 GLY A O   1 
ATOM   3902  N  N   . LYS A 1 511 ? 195.742 189.858 195.227 1.00 112.87 ? 511 LYS A N   1 
ATOM   3903  C  CA  . LYS A 1 511 ? 196.566 189.185 196.219 1.00 110.45 ? 511 LYS A CA  1 
ATOM   3904  C  C   . LYS A 1 511 ? 197.488 190.183 196.905 1.00 108.95 ? 511 LYS A C   1 
ATOM   3905  O  O   . LYS A 1 511 ? 198.008 191.108 196.276 1.00 110.95 ? 511 LYS A O   1 
ATOM   3906  C  CB  . LYS A 1 511 ? 197.382 188.073 195.564 1.00 103.20 ? 511 LYS A CB  1 
ATOM   3907  C  CG  . LYS A 1 511 ? 196.572 187.157 194.677 1.00 101.19 ? 511 LYS A CG  1 
ATOM   3908  C  CD  . LYS A 1 511 ? 195.421 186.541 195.448 1.00 103.86 ? 511 LYS A CD  1 
ATOM   3909  C  CE  . LYS A 1 511 ? 194.722 185.465 194.639 1.00 109.85 ? 511 LYS A CE  1 
ATOM   3910  N  NZ  . LYS A 1 511 ? 193.535 184.920 195.355 1.00 114.35 ? 511 LYS A NZ  1 
ATOM   3911  N  N   . ASN A 1 512 ? 197.685 189.994 198.207 1.00 101.26 ? 512 ASN A N   1 
ATOM   3912  C  CA  . ASN A 1 512 ? 198.546 190.884 198.966 1.00 97.88  ? 512 ASN A CA  1 
ATOM   3913  C  C   . ASN A 1 512 ? 200.001 190.688 198.557 1.00 95.80  ? 512 ASN A C   1 
ATOM   3914  O  O   . ASN A 1 512 ? 200.351 189.756 197.830 1.00 96.84  ? 512 ASN A O   1 
ATOM   3915  C  CB  . ASN A 1 512 ? 198.290 190.700 200.472 1.00 100.79 ? 512 ASN A CB  1 
ATOM   3916  C  CG  . ASN A 1 512 ? 199.173 189.631 201.145 1.00 102.40 ? 512 ASN A CG  1 
ATOM   3917  O  OD1 . ASN A 1 512 ? 200.114 189.085 200.576 1.00 101.11 ? 512 ASN A OD1 1 
ATOM   3918  N  ND2 . ASN A 1 512 ? 198.843 189.338 202.398 1.00 103.33 ? 512 ASN A ND2 1 
ATOM   3919  N  N   . ARG A 1 513 ? 200.863 191.582 199.045 1.00 98.24  ? 513 ARG A N   1 
ATOM   3920  C  CA  . ARG A 1 513 ? 202.266 191.536 198.643 1.00 103.01 ? 513 ARG A CA  1 
ATOM   3921  C  C   . ARG A 1 513 ? 202.943 190.254 199.123 1.00 102.88 ? 513 ARG A C   1 
ATOM   3922  O  O   . ARG A 1 513 ? 203.773 189.678 198.408 1.00 100.93 ? 513 ARG A O   1 
ATOM   3923  C  CB  . ARG A 1 513 ? 203.006 192.777 199.154 1.00 105.90 ? 513 ARG A CB  1 
ATOM   3924  C  CG  . ARG A 1 513 ? 203.390 192.758 200.627 1.00 104.21 ? 513 ARG A CG  1 
ATOM   3925  C  CD  . ARG A 1 513 ? 204.434 193.821 200.938 1.00 107.18 ? 513 ARG A CD  1 
ATOM   3926  N  NE  . ARG A 1 513 ? 205.070 193.608 202.233 1.00 108.46 ? 513 ARG A NE  1 
ATOM   3927  C  CZ  . ARG A 1 513 ? 204.548 193.972 203.396 1.00 111.93 ? 513 ARG A CZ  1 
ATOM   3928  N  NH1 . ARG A 1 513 ? 203.372 194.574 203.467 1.00 119.44 ? 513 ARG A NH1 1 
ATOM   3929  N  NH2 . ARG A 1 513 ? 205.222 193.727 204.515 1.00 107.40 ? 513 ARG A NH2 1 
ATOM   3930  N  N   . ASP A 1 514 ? 202.587 189.781 200.321 1.00 104.44 ? 514 ASP A N   1 
ATOM   3931  C  CA  . ASP A 1 514 ? 203.255 188.610 200.876 1.00 103.28 ? 514 ASP A CA  1 
ATOM   3932  C  C   . ASP A 1 514 ? 203.048 187.390 199.992 1.00 97.00  ? 514 ASP A C   1 
ATOM   3933  O  O   . ASP A 1 514 ? 203.984 186.617 199.759 1.00 93.97  ? 514 ASP A O   1 
ATOM   3934  C  CB  . ASP A 1 514 ? 202.752 188.341 202.294 1.00 105.74 ? 514 ASP A CB  1 
ATOM   3935  C  CG  . ASP A 1 514 ? 203.271 189.352 203.298 1.00 110.62 ? 514 ASP A CG  1 
ATOM   3936  O  OD1 . ASP A 1 514 ? 204.171 190.140 202.939 1.00 110.56 ? 514 ASP A OD1 1 
ATOM   3937  O  OD2 . ASP A 1 514 ? 202.777 189.359 204.445 1.00 113.52 ? 514 ASP A OD2 1 
ATOM   3938  N  N   . TYR A 1 515 ? 201.829 187.201 199.488 1.00 95.67  ? 515 TYR A N   1 
ATOM   3939  C  CA  . TYR A 1 515 ? 201.584 186.097 198.570 1.00 92.37  ? 515 TYR A CA  1 
ATOM   3940  C  C   . TYR A 1 515 ? 202.419 186.245 197.311 1.00 89.17  ? 515 TYR A C   1 
ATOM   3941  O  O   . TYR A 1 515 ? 202.954 185.260 196.793 1.00 87.15  ? 515 TYR A O   1 
ATOM   3942  C  CB  . TYR A 1 515 ? 200.101 186.021 198.210 1.00 96.85  ? 515 TYR A CB  1 
ATOM   3943  C  CG  . TYR A 1 515 ? 199.774 184.932 197.213 1.00 94.49  ? 515 TYR A CG  1 
ATOM   3944  C  CD1 . TYR A 1 515 ? 199.804 185.177 195.846 1.00 89.68  ? 515 TYR A CD1 1 
ATOM   3945  C  CD2 . TYR A 1 515 ? 199.429 183.659 197.640 1.00 94.62  ? 515 TYR A CD2 1 
ATOM   3946  C  CE1 . TYR A 1 515 ? 199.510 184.190 194.941 1.00 88.82  ? 515 TYR A CE1 1 
ATOM   3947  C  CE2 . TYR A 1 515 ? 199.128 182.665 196.737 1.00 92.20  ? 515 TYR A CE2 1 
ATOM   3948  C  CZ  . TYR A 1 515 ? 199.168 182.937 195.390 1.00 89.91  ? 515 TYR A CZ  1 
ATOM   3949  O  OH  . TYR A 1 515 ? 198.871 181.945 194.489 1.00 91.87  ? 515 TYR A OH  1 
ATOM   3950  N  N   . LEU A 1 516 ? 202.518 187.469 196.792 1.00 92.13  ? 516 LEU A N   1 
ATOM   3951  C  CA  . LEU A 1 516 ? 203.307 187.703 195.590 1.00 91.12  ? 516 LEU A CA  1 
ATOM   3952  C  C   . LEU A 1 516 ? 204.751 187.271 195.797 1.00 92.24  ? 516 LEU A C   1 
ATOM   3953  O  O   . LEU A 1 516 ? 205.293 186.495 195.004 1.00 92.14  ? 516 LEU A O   1 
ATOM   3954  C  CB  . LEU A 1 516 ? 203.230 189.175 195.184 1.00 89.09  ? 516 LEU A CB  1 
ATOM   3955  C  CG  . LEU A 1 516 ? 202.034 189.676 194.367 1.00 90.50  ? 516 LEU A CG  1 
ATOM   3956  C  CD1 . LEU A 1 516 ? 200.735 188.973 194.719 1.00 95.60  ? 516 LEU A CD1 1 
ATOM   3957  C  CD2 . LEU A 1 516 ? 201.871 191.180 194.532 1.00 92.63  ? 516 LEU A CD2 1 
ATOM   3958  N  N   . LEU A 1 517 ? 205.381 187.731 196.882 1.00 90.59  ? 517 LEU A N   1 
ATOM   3959  C  CA  . LEU A 1 517 ? 206.764 187.331 197.130 1.00 85.90  ? 517 LEU A CA  1 
ATOM   3960  C  C   . LEU A 1 517 ? 206.886 185.835 197.395 1.00 85.12  ? 517 LEU A C   1 
ATOM   3961  O  O   . LEU A 1 517 ? 207.828 185.194 196.916 1.00 83.34  ? 517 LEU A O   1 
ATOM   3962  C  CB  . LEU A 1 517 ? 207.364 188.124 198.292 1.00 87.50  ? 517 LEU A CB  1 
ATOM   3963  C  CG  . LEU A 1 517 ? 207.769 189.582 198.058 1.00 89.82  ? 517 LEU A CG  1 
ATOM   3964  C  CD1 . LEU A 1 517 ? 208.380 189.746 196.675 1.00 91.28  ? 517 LEU A CD1 1 
ATOM   3965  C  CD2 . LEU A 1 517 ? 206.633 190.558 198.273 1.00 92.00  ? 517 LEU A CD2 1 
ATOM   3966  N  N   . SER A 1 518 ? 205.955 185.257 198.157 1.00 87.67  ? 518 SER A N   1 
ATOM   3967  C  CA  . SER A 1 518 ? 206.063 183.842 198.501 1.00 92.04  ? 518 SER A CA  1 
ATOM   3968  C  C   . SER A 1 518 ? 205.970 182.968 197.258 1.00 92.40  ? 518 SER A C   1 
ATOM   3969  O  O   . SER A 1 518 ? 206.814 182.094 197.027 1.00 91.34  ? 518 SER A O   1 
ATOM   3970  C  CB  . SER A 1 518 ? 204.977 183.467 199.509 1.00 95.34  ? 518 SER A CB  1 
ATOM   3971  O  OG  . SER A 1 518 ? 205.122 182.125 199.942 1.00 97.81  ? 518 SER A OG  1 
ATOM   3972  N  N   . THR A 1 519 ? 204.954 183.202 196.431 1.00 92.67  ? 519 THR A N   1 
ATOM   3973  C  CA  . THR A 1 519 ? 204.812 182.411 195.219 1.00 89.50  ? 519 THR A CA  1 
ATOM   3974  C  C   . THR A 1 519 ? 205.931 182.706 194.236 1.00 82.31  ? 519 THR A C   1 
ATOM   3975  O  O   . THR A 1 519 ? 206.379 181.810 193.516 1.00 77.89  ? 519 THR A O   1 
ATOM   3976  C  CB  . THR A 1 519 ? 203.451 182.670 194.584 1.00 94.12  ? 519 THR A CB  1 
ATOM   3977  O  OG1 . THR A 1 519 ? 203.263 184.080 194.407 1.00 93.17  ? 519 THR A OG1 1 
ATOM   3978  C  CG2 . THR A 1 519 ? 202.363 182.124 195.479 1.00 93.21  ? 519 THR A CG2 1 
ATOM   3979  N  N   . ALA A 1 520 ? 206.391 183.956 194.180 1.00 80.14  ? 520 ALA A N   1 
ATOM   3980  C  CA  . ALA A 1 520 ? 207.493 184.272 193.290 1.00 75.50  ? 520 ALA A CA  1 
ATOM   3981  C  C   . ALA A 1 520 ? 208.734 183.500 193.688 1.00 77.03  ? 520 ALA A C   1 
ATOM   3982  O  O   . ALA A 1 520 ? 209.460 182.999 192.828 1.00 74.54  ? 520 ALA A O   1 
ATOM   3983  C  CB  . ALA A 1 520 ? 207.758 185.774 193.296 1.00 74.07  ? 520 ALA A CB  1 
ATOM   3984  N  N   . HIS A 1 521 ? 208.983 183.366 194.992 1.00 83.47  ? 521 HIS A N   1 
ATOM   3985  C  CA  . HIS A 1 521 ? 210.120 182.559 195.416 1.00 86.09  ? 521 HIS A CA  1 
ATOM   3986  C  C   . HIS A 1 521 ? 209.865 181.074 195.196 1.00 86.98  ? 521 HIS A C   1 
ATOM   3987  O  O   . HIS A 1 521 ? 210.813 180.308 194.986 1.00 86.44  ? 521 HIS A O   1 
ATOM   3988  C  CB  . HIS A 1 521 ? 210.478 182.826 196.877 1.00 81.16  ? 521 HIS A CB  1 
ATOM   3989  C  CG  . HIS A 1 521 ? 211.847 182.347 197.239 1.00 80.76  ? 521 HIS A CG  1 
ATOM   3990  N  ND1 . HIS A 1 521 ? 212.988 183.049 196.918 1.00 82.82  ? 521 HIS A ND1 1 
ATOM   3991  C  CD2 . HIS A 1 521 ? 212.264 181.214 197.850 1.00 80.83  ? 521 HIS A CD2 1 
ATOM   3992  C  CE1 . HIS A 1 521 ? 214.047 182.380 197.334 1.00 79.63  ? 521 HIS A CE1 1 
ATOM   3993  N  NE2 . HIS A 1 521 ? 213.635 181.263 197.904 1.00 80.32  ? 521 HIS A NE2 1 
ATOM   3994  N  N   . ASN A 1 522 ? 208.603 180.644 195.237 1.00 87.01  ? 522 ASN A N   1 
ATOM   3995  C  CA  . ASN A 1 522 ? 208.308 179.266 194.862 1.00 89.97  ? 522 ASN A CA  1 
ATOM   3996  C  C   . ASN A 1 522 ? 208.698 179.009 193.412 1.00 85.32  ? 522 ASN A C   1 
ATOM   3997  O  O   . ASN A 1 522 ? 209.350 178.007 193.103 1.00 83.75  ? 522 ASN A O   1 
ATOM   3998  C  CB  . ASN A 1 522 ? 206.828 178.960 195.085 1.00 93.16  ? 522 ASN A CB  1 
ATOM   3999  C  CG  . ASN A 1 522 ? 206.389 177.674 194.411 1.00 95.22  ? 522 ASN A CG  1 
ATOM   4000  O  OD1 . ASN A 1 522 ? 207.112 176.678 194.415 1.00 90.83  ? 522 ASN A OD1 1 
ATOM   4001  N  ND2 . ASN A 1 522 ? 205.196 177.690 193.827 1.00 95.19  ? 522 ASN A ND2 1 
ATOM   4002  N  N   . ALA A 1 523 ? 208.328 179.925 192.515 1.00 79.45  ? 523 ALA A N   1 
ATOM   4003  C  CA  . ALA A 1 523 ? 208.715 179.803 191.113 1.00 75.51  ? 523 ALA A CA  1 
ATOM   4004  C  C   . ALA A 1 523 ? 210.218 179.925 190.955 1.00 77.24  ? 523 ALA A C   1 
ATOM   4005  O  O   . ALA A 1 523 ? 210.816 179.272 190.094 1.00 78.57  ? 523 ALA A O   1 
ATOM   4006  C  CB  . ALA A 1 523 ? 208.004 180.860 190.276 1.00 66.68  ? 523 ALA A CB  1 
ATOM   4007  N  N   . MET A 1 524 ? 210.836 180.771 191.776 1.00 80.58  ? 524 MET A N   1 
ATOM   4008  C  CA  . MET A 1 524 ? 212.286 180.904 191.827 1.00 83.35  ? 524 MET A CA  1 
ATOM   4009  C  C   . MET A 1 524 ? 212.928 179.545 192.071 1.00 83.78  ? 524 MET A C   1 
ATOM   4010  O  O   . MET A 1 524 ? 213.762 179.080 191.289 1.00 83.95  ? 524 MET A O   1 
ATOM   4011  C  CB  . MET A 1 524 ? 212.629 181.902 192.944 1.00 83.36  ? 524 MET A CB  1 
ATOM   4012  C  CG  . MET A 1 524 ? 214.046 182.456 193.097 1.00 80.25  ? 524 MET A CG  1 
ATOM   4013  S  SD  . MET A 1 524 ? 215.010 182.834 191.631 1.00 86.64  ? 524 MET A SD  1 
ATOM   4014  C  CE  . MET A 1 524 ? 215.815 181.275 191.321 1.00 78.22  ? 524 MET A CE  1 
ATOM   4015  N  N   . ASP A 1 525 ? 212.488 178.863 193.128 1.00 81.25  ? 525 ASP A N   1 
ATOM   4016  C  CA  . ASP A 1 525 ? 213.039 177.550 193.438 1.00 81.94  ? 525 ASP A CA  1 
ATOM   4017  C  C   . ASP A 1 525 ? 212.730 176.556 192.330 1.00 79.29  ? 525 ASP A C   1 
ATOM   4018  O  O   . ASP A 1 525 ? 213.595 175.765 191.932 1.00 82.64  ? 525 ASP A O   1 
ATOM   4019  C  CB  . ASP A 1 525 ? 212.492 177.055 194.776 1.00 92.08  ? 525 ASP A CB  1 
ATOM   4020  C  CG  . ASP A 1 525 ? 213.554 177.004 195.856 1.00 101.18 ? 525 ASP A CG  1 
ATOM   4021  O  OD1 . ASP A 1 525 ? 214.739 177.236 195.538 1.00 97.75  ? 525 ASP A OD1 1 
ATOM   4022  O  OD2 . ASP A 1 525 ? 213.203 176.732 197.024 1.00 104.42 ? 525 ASP A OD2 1 
ATOM   4023  N  N   . TYR A 1 526 ? 211.505 176.599 191.805 1.00 76.65  ? 526 TYR A N   1 
ATOM   4024  C  CA  . TYR A 1 526 ? 211.085 175.635 190.796 1.00 80.38  ? 526 TYR A CA  1 
ATOM   4025  C  C   . TYR A 1 526 ? 211.943 175.736 189.543 1.00 82.43  ? 526 TYR A C   1 
ATOM   4026  O  O   . TYR A 1 526 ? 212.359 174.715 188.982 1.00 83.63  ? 526 TYR A O   1 
ATOM   4027  C  CB  . TYR A 1 526 ? 209.613 175.861 190.463 1.00 80.24  ? 526 TYR A CB  1 
ATOM   4028  C  CG  . TYR A 1 526 ? 208.883 174.639 189.976 1.00 76.88  ? 526 TYR A CG  1 
ATOM   4029  C  CD1 . TYR A 1 526 ? 208.989 173.436 190.647 1.00 76.80  ? 526 TYR A CD1 1 
ATOM   4030  C  CD2 . TYR A 1 526 ? 208.062 174.699 188.862 1.00 76.44  ? 526 TYR A CD2 1 
ATOM   4031  C  CE1 . TYR A 1 526 ? 208.315 172.319 190.211 1.00 78.56  ? 526 TYR A CE1 1 
ATOM   4032  C  CE2 . TYR A 1 526 ? 207.383 173.592 188.419 1.00 74.58  ? 526 TYR A CE2 1 
ATOM   4033  C  CZ  . TYR A 1 526 ? 207.511 172.403 189.096 1.00 78.71  ? 526 TYR A CZ  1 
ATOM   4034  O  OH  . TYR A 1 526 ? 206.834 171.289 188.655 1.00 81.06  ? 526 TYR A OH  1 
ATOM   4035  N  N   . ILE A 1 527 ? 212.226 176.961 189.093 1.00 80.39  ? 527 ILE A N   1 
ATOM   4036  C  CA  . ILE A 1 527 ? 213.054 177.167 187.908 1.00 75.19  ? 527 ILE A CA  1 
ATOM   4037  C  C   . ILE A 1 527 ? 214.536 177.115 188.220 1.00 73.39  ? 527 ILE A C   1 
ATOM   4038  O  O   . ILE A 1 527 ? 215.355 177.085 187.294 1.00 66.94  ? 527 ILE A O   1 
ATOM   4039  C  CB  . ILE A 1 527 ? 212.710 178.512 187.246 1.00 71.46  ? 527 ILE A CB  1 
ATOM   4040  C  CG1 . ILE A 1 527 ? 213.067 178.489 185.757 1.00 68.25  ? 527 ILE A CG1 1 
ATOM   4041  C  CG2 . ILE A 1 527 ? 213.421 179.641 187.956 1.00 72.39  ? 527 ILE A CG2 1 
ATOM   4042  C  CD1 . ILE A 1 527 ? 212.299 177.457 184.959 1.00 67.93  ? 527 ILE A CD1 1 
ATOM   4043  N  N   . ARG A 1 528 ? 214.906 177.104 189.499 1.00 79.28  ? 528 ARG A N   1 
ATOM   4044  C  CA  . ARG A 1 528 ? 216.308 177.014 189.879 1.00 81.53  ? 528 ARG A CA  1 
ATOM   4045  C  C   . ARG A 1 528 ? 216.791 175.574 189.993 1.00 82.01  ? 528 ARG A C   1 
ATOM   4046  O  O   . ARG A 1 528 ? 217.779 175.206 189.353 1.00 84.19  ? 528 ARG A O   1 
ATOM   4047  C  CB  . ARG A 1 528 ? 216.542 177.749 191.202 1.00 82.76  ? 528 ARG A CB  1 
ATOM   4048  C  CG  . ARG A 1 528 ? 217.918 177.518 191.799 1.00 85.06  ? 528 ARG A CG  1 
ATOM   4049  C  CD  . ARG A 1 528 ? 219.001 178.170 190.957 1.00 86.65  ? 528 ARG A CD  1 
ATOM   4050  N  NE  . ARG A 1 528 ? 219.045 179.616 191.139 1.00 88.69  ? 528 ARG A NE  1 
ATOM   4051  C  CZ  . ARG A 1 528 ? 219.631 180.224 192.161 1.00 88.60  ? 528 ARG A CZ  1 
ATOM   4052  N  NH1 . ARG A 1 528 ? 220.236 179.540 193.118 1.00 90.24  ? 528 ARG A NH1 1 
ATOM   4053  N  NH2 . ARG A 1 528 ? 219.611 181.552 192.224 1.00 85.43  ? 528 ARG A NH2 1 
ATOM   4054  N  N   . LYS A 1 529 ? 216.118 174.746 190.795 1.00 81.32  ? 529 LYS A N   1 
ATOM   4055  C  CA  . LYS A 1 529 ? 216.665 173.410 191.013 1.00 82.41  ? 529 LYS A CA  1 
ATOM   4056  C  C   . LYS A 1 529 ? 216.543 172.525 189.782 1.00 81.49  ? 529 LYS A C   1 
ATOM   4057  O  O   . LYS A 1 529 ? 217.179 171.468 189.733 1.00 86.70  ? 529 LYS A O   1 
ATOM   4058  C  CB  . LYS A 1 529 ? 216.007 172.720 192.214 1.00 84.38  ? 529 LYS A CB  1 
ATOM   4059  C  CG  . LYS A 1 529 ? 214.510 172.906 192.370 1.00 83.34  ? 529 LYS A CG  1 
ATOM   4060  C  CD  . LYS A 1 529 ? 213.741 171.951 191.473 1.00 85.29  ? 529 LYS A CD  1 
ATOM   4061  C  CE  . LYS A 1 529 ? 212.259 172.273 191.434 1.00 84.99  ? 529 LYS A CE  1 
ATOM   4062  N  NZ  . LYS A 1 529 ? 211.644 171.816 190.155 1.00 86.17  ? 529 LYS A NZ  1 
ATOM   4063  N  N   . ASN A 1 530 ? 215.755 172.931 188.789 1.00 76.28  ? 530 ASN A N   1 
ATOM   4064  C  CA  . ASN A 1 530 ? 215.665 172.165 187.556 1.00 79.81  ? 530 ASN A CA  1 
ATOM   4065  C  C   . ASN A 1 530 ? 216.933 172.271 186.718 1.00 80.28  ? 530 ASN A C   1 
ATOM   4066  O  O   . ASN A 1 530 ? 217.120 171.470 185.798 1.00 80.66  ? 530 ASN A O   1 
ATOM   4067  C  CB  . ASN A 1 530 ? 214.460 172.635 186.743 1.00 84.81  ? 530 ASN A CB  1 
ATOM   4068  C  CG  . ASN A 1 530 ? 213.141 172.288 187.402 1.00 84.44  ? 530 ASN A CG  1 
ATOM   4069  O  OD1 . ASN A 1 530 ? 213.108 171.613 188.426 1.00 85.76  ? 530 ASN A OD1 1 
ATOM   4070  N  ND2 . ASN A 1 530 ? 212.046 172.755 186.819 1.00 79.97  ? 530 ASN A ND2 1 
ATOM   4071  N  N   . GLY A 1 531 ? 217.799 173.240 187.008 1.00 79.77  ? 531 GLY A N   1 
ATOM   4072  C  CA  . GLY A 1 531 ? 219.013 173.436 186.237 1.00 82.37  ? 531 GLY A CA  1 
ATOM   4073  C  C   . GLY A 1 531 ? 219.361 174.897 186.023 1.00 85.26  ? 531 GLY A C   1 
ATOM   4074  O  O   . GLY A 1 531 ? 220.506 175.231 185.704 1.00 84.98  ? 531 GLY A O   1 
ATOM   4075  N  N   . GLY A 1 532 ? 218.380 175.777 186.197 1.00 84.37  ? 532 GLY A N   1 
ATOM   4076  C  CA  . GLY A 1 532 ? 218.608 177.198 186.064 1.00 78.03  ? 532 GLY A CA  1 
ATOM   4077  C  C   . GLY A 1 532 ? 218.597 177.685 184.626 1.00 75.72  ? 532 GLY A C   1 
ATOM   4078  O  O   . GLY A 1 532 ? 218.172 177.000 183.693 1.00 71.04  ? 532 GLY A O   1 
ATOM   4079  N  N   . ASN A 1 533 ? 219.078 178.918 184.466 1.00 79.04  ? 533 ASN A N   1 
ATOM   4080  C  CA  . ASN A 1 533 ? 219.186 179.580 183.165 1.00 76.31  ? 533 ASN A CA  1 
ATOM   4081  C  C   . ASN A 1 533 ? 217.834 179.655 182.464 1.00 70.57  ? 533 ASN A C   1 
ATOM   4082  O  O   . ASN A 1 533 ? 217.743 179.532 181.243 1.00 74.06  ? 533 ASN A O   1 
ATOM   4083  C  CB  . ASN A 1 533 ? 220.220 178.886 182.275 1.00 77.02  ? 533 ASN A CB  1 
ATOM   4084  C  CG  . ASN A 1 533 ? 220.780 179.802 181.205 1.00 76.93  ? 533 ASN A CG  1 
ATOM   4085  O  OD1 . ASN A 1 533 ? 220.935 181.001 181.419 1.00 80.48  ? 533 ASN A OD1 1 
ATOM   4086  N  ND2 . ASN A 1 533 ? 221.091 179.238 180.047 1.00 75.82  ? 533 ASN A ND2 1 
ATOM   4087  N  N   . GLY A 1 534 ? 216.774 179.882 183.236 1.00 67.38  ? 534 GLY A N   1 
ATOM   4088  C  CA  . GLY A 1 534 ? 215.448 179.928 182.662 1.00 60.65  ? 534 GLY A CA  1 
ATOM   4089  C  C   . GLY A 1 534 ? 214.519 180.827 183.447 1.00 55.51  ? 534 GLY A C   1 
ATOM   4090  O  O   . GLY A 1 534 ? 214.864 181.345 184.511 1.00 63.02  ? 534 GLY A O   1 
ATOM   4091  N  N   . TRP A 1 535 ? 213.324 181.007 182.906 1.00 48.33  ? 535 TRP A N   1 
ATOM   4092  C  CA  . TRP A 1 535 ? 212.297 181.797 183.555 1.00 54.24  ? 535 TRP A CA  1 
ATOM   4093  C  C   . TRP A 1 535 ? 211.005 180.999 183.582 1.00 51.50  ? 535 TRP A C   1 
ATOM   4094  O  O   . TRP A 1 535 ? 210.819 180.062 182.804 1.00 55.26  ? 535 TRP A O   1 
ATOM   4095  C  CB  . TRP A 1 535 ? 212.090 183.137 182.840 1.00 57.79  ? 535 TRP A CB  1 
ATOM   4096  C  CG  . TRP A 1 535 ? 211.529 182.994 181.467 1.00 56.58  ? 535 TRP A CG  1 
ATOM   4097  C  CD1 . TRP A 1 535 ? 212.192 182.609 180.349 1.00 55.50  ? 535 TRP A CD1 1 
ATOM   4098  C  CD2 . TRP A 1 535 ? 210.180 183.246 181.068 1.00 53.43  ? 535 TRP A CD2 1 
ATOM   4099  N  NE1 . TRP A 1 535 ? 211.343 182.597 179.279 1.00 52.28  ? 535 TRP A NE1 1 
ATOM   4100  C  CE2 . TRP A 1 535 ? 210.099 182.986 179.696 1.00 50.85  ? 535 TRP A CE2 1 
ATOM   4101  C  CE3 . TRP A 1 535 ? 209.034 183.661 181.743 1.00 54.63  ? 535 TRP A CE3 1 
ATOM   4102  C  CZ2 . TRP A 1 535 ? 208.917 183.128 178.984 1.00 53.40  ? 535 TRP A CZ2 1 
ATOM   4103  C  CZ3 . TRP A 1 535 ? 207.865 183.799 181.039 1.00 53.24  ? 535 TRP A CZ3 1 
ATOM   4104  C  CH2 . TRP A 1 535 ? 207.813 183.537 179.674 1.00 52.79  ? 535 TRP A CH2 1 
ATOM   4105  N  N   . GLN A 1 536 ? 210.118 181.358 184.503 1.00 48.05  ? 536 GLN A N   1 
ATOM   4106  C  CA  . GLN A 1 536 ? 208.857 180.642 184.607 1.00 48.03  ? 536 GLN A CA  1 
ATOM   4107  C  C   . GLN A 1 536 ? 207.854 181.484 185.375 1.00 50.74  ? 536 GLN A C   1 
ATOM   4108  O  O   . GLN A 1 536 ? 208.228 182.364 186.154 1.00 57.58  ? 536 GLN A O   1 
ATOM   4109  C  CB  . GLN A 1 536 ? 209.059 179.289 185.289 1.00 54.78  ? 536 GLN A CB  1 
ATOM   4110  C  CG  . GLN A 1 536 ? 208.000 178.256 184.989 1.00 59.43  ? 536 GLN A CG  1 
ATOM   4111  C  CD  . GLN A 1 536 ? 207.999 177.132 186.000 1.00 64.13  ? 536 GLN A CD  1 
ATOM   4112  O  OE1 . GLN A 1 536 ? 208.749 177.160 186.971 1.00 66.75  ? 536 GLN A OE1 1 
ATOM   4113  N  NE2 . GLN A 1 536 ? 207.162 176.131 185.774 1.00 62.01  ? 536 GLN A NE2 1 
ATOM   4114  N  N   . PHE A 1 537 ? 206.575 181.211 185.142 1.00 47.86  ? 537 PHE A N   1 
ATOM   4115  C  CA  . PHE A 1 537 ? 205.518 181.679 186.022 1.00 48.63  ? 537 PHE A CA  1 
ATOM   4116  C  C   . PHE A 1 537 ? 205.412 180.711 187.188 1.00 54.62  ? 537 PHE A C   1 
ATOM   4117  O  O   . PHE A 1 537 ? 206.135 179.718 187.273 1.00 59.82  ? 537 PHE A O   1 
ATOM   4118  C  CB  . PHE A 1 537 ? 204.173 181.784 185.295 1.00 55.99  ? 537 PHE A CB  1 
ATOM   4119  C  CG  . PHE A 1 537 ? 204.032 182.986 184.396 1.00 59.66  ? 537 PHE A CG  1 
ATOM   4120  C  CD1 . PHE A 1 537 ? 203.033 183.915 184.626 1.00 57.44  ? 537 PHE A CD1 1 
ATOM   4121  C  CD2 . PHE A 1 537 ? 204.869 183.170 183.306 1.00 61.23  ? 537 PHE A CD2 1 
ATOM   4122  C  CE1 . PHE A 1 537 ? 202.882 185.008 183.798 1.00 55.35  ? 537 PHE A CE1 1 
ATOM   4123  C  CE2 . PHE A 1 537 ? 204.725 184.269 182.478 1.00 55.53  ? 537 PHE A CE2 1 
ATOM   4124  C  CZ  . PHE A 1 537 ? 203.733 185.184 182.724 1.00 54.25  ? 537 PHE A CZ  1 
ATOM   4125  N  N   . PHE A 1 538 ? 204.491 180.986 188.097 1.00 59.15  ? 538 PHE A N   1 
ATOM   4126  C  CA  . PHE A 1 538 ? 204.267 180.070 189.204 1.00 72.47  ? 538 PHE A CA  1 
ATOM   4127  C  C   . PHE A 1 538 ? 202.981 179.274 189.064 1.00 79.42  ? 538 PHE A C   1 
ATOM   4128  O  O   . PHE A 1 538 ? 202.892 178.164 189.597 1.00 81.58  ? 538 PHE A O   1 
ATOM   4129  C  CB  . PHE A 1 538 ? 204.242 180.835 190.532 1.00 79.75  ? 538 PHE A CB  1 
ATOM   4130  C  CG  . PHE A 1 538 ? 202.865 181.227 190.977 1.00 85.14  ? 538 PHE A CG  1 
ATOM   4131  C  CD1 . PHE A 1 538 ? 202.189 182.260 190.350 1.00 84.39  ? 538 PHE A CD1 1 
ATOM   4132  C  CD2 . PHE A 1 538 ? 202.253 180.568 192.028 1.00 83.72  ? 538 PHE A CD2 1 
ATOM   4133  C  CE1 . PHE A 1 538 ? 200.926 182.620 190.753 1.00 87.91  ? 538 PHE A CE1 1 
ATOM   4134  C  CE2 . PHE A 1 538 ? 200.991 180.925 192.440 1.00 86.84  ? 538 PHE A CE2 1 
ATOM   4135  C  CZ  . PHE A 1 538 ? 200.324 181.954 191.801 1.00 91.88  ? 538 PHE A CZ  1 
ATOM   4136  N  N   . SER A 1 539 ? 201.990 179.812 188.352 1.00 82.05  ? 539 SER A N   1 
ATOM   4137  C  CA  . SER A 1 539 ? 200.644 179.296 188.140 1.00 82.26  ? 539 SER A CA  1 
ATOM   4138  C  C   . SER A 1 539 ? 200.527 178.622 186.780 1.00 77.71  ? 539 SER A C   1 
ATOM   4139  O  O   . SER A 1 539 ? 200.809 179.244 185.752 1.00 77.30  ? 539 SER A O   1 
ATOM   4140  C  CB  . SER A 1 539 ? 199.613 180.414 188.223 1.00 79.94  ? 539 SER A CB  1 
ATOM   4141  O  OG  . SER A 1 539 ? 198.302 179.880 188.253 1.00 74.09  ? 539 SER A OG  1 
ATOM   4142  N  N   . PRO A 1 540 ? 200.114 177.356 186.754 1.00 76.84  ? 540 PRO A N   1 
ATOM   4143  C  CA  . PRO A 1 540 ? 199.697 176.732 185.497 1.00 76.06  ? 540 PRO A CA  1 
ATOM   4144  C  C   . PRO A 1 540 ? 198.478 177.380 184.861 1.00 77.77  ? 540 PRO A C   1 
ATOM   4145  O  O   . PRO A 1 540 ? 198.130 177.023 183.733 1.00 73.54  ? 540 PRO A O   1 
ATOM   4146  C  CB  . PRO A 1 540 ? 199.385 175.288 185.922 1.00 72.95  ? 540 PRO A CB  1 
ATOM   4147  C  CG  . PRO A 1 540 ? 200.195 175.073 187.150 1.00 76.16  ? 540 PRO A CG  1 
ATOM   4148  C  CD  . PRO A 1 540 ? 200.182 176.387 187.860 1.00 77.31  ? 540 PRO A CD  1 
ATOM   4149  N  N   . ALA A 1 541 ? 197.824 178.311 185.559 1.00 80.19  ? 541 ALA A N   1 
ATOM   4150  C  CA  . ALA A 1 541 ? 196.713 179.066 184.997 1.00 82.39  ? 541 ALA A CA  1 
ATOM   4151  C  C   . ALA A 1 541 ? 197.165 180.239 184.136 1.00 83.83  ? 541 ALA A C   1 
ATOM   4152  O  O   . ALA A 1 541 ? 196.324 180.859 183.476 1.00 83.18  ? 541 ALA A O   1 
ATOM   4153  C  CB  . ALA A 1 541 ? 195.803 179.575 186.117 1.00 76.98  ? 541 ALA A CB  1 
ATOM   4154  N  N   . MET A 1 542 ? 198.464 180.551 184.119 1.00 81.15  ? 542 MET A N   1 
ATOM   4155  C  CA  . MET A 1 542 ? 198.985 181.602 183.255 1.00 73.37  ? 542 MET A CA  1 
ATOM   4156  C  C   . MET A 1 542 ? 200.201 181.140 182.468 1.00 65.26  ? 542 MET A C   1 
ATOM   4157  O  O   . MET A 1 542 ? 200.698 181.895 181.625 1.00 67.18  ? 542 MET A O   1 
ATOM   4158  C  CB  . MET A 1 542 ? 199.343 182.845 184.074 1.00 78.56  ? 542 MET A CB  1 
ATOM   4159  C  CG  . MET A 1 542 ? 198.326 183.965 183.972 1.00 82.53  ? 542 MET A CG  1 
ATOM   4160  S  SD  . MET A 1 542 ? 197.024 183.825 185.210 1.00 95.47  ? 542 MET A SD  1 
ATOM   4161  C  CE  . MET A 1 542 ? 197.987 183.803 186.721 1.00 87.41  ? 542 MET A CE  1 
ATOM   4162  N  N   . ASN A 1 543 ? 200.705 179.943 182.728 1.00 61.83  ? 543 ASN A N   1 
ATOM   4163  C  CA  . ASN A 1 543 ? 201.808 179.373 181.981 1.00 60.08  ? 543 ASN A CA  1 
ATOM   4164  C  C   . ASN A 1 543 ? 201.353 178.676 180.708 1.00 69.54  ? 543 ASN A C   1 
ATOM   4165  O  O   . ASN A 1 543 ? 202.131 178.581 179.746 1.00 72.06  ? 543 ASN A O   1 
ATOM   4166  C  CB  . ASN A 1 543 ? 202.562 178.386 182.862 1.00 58.93  ? 543 ASN A CB  1 
ATOM   4167  C  CG  . ASN A 1 543 ? 203.853 177.948 182.254 1.00 58.32  ? 543 ASN A CG  1 
ATOM   4168  O  OD1 . ASN A 1 543 ? 203.879 177.067 181.399 1.00 61.46  ? 543 ASN A OD1 1 
ATOM   4169  N  ND2 . ASN A 1 543 ? 204.945 178.557 182.685 1.00 57.87  ? 543 ASN A ND2 1 
ATOM   4170  N  N   . GLU A 1 544 ? 200.110 178.200 180.673 1.00 73.87  ? 544 GLU A N   1 
ATOM   4171  C  CA  . GLU A 1 544 ? 199.591 177.606 179.453 1.00 72.27  ? 544 GLU A CA  1 
ATOM   4172  C  C   . GLU A 1 544 ? 199.547 178.602 178.303 1.00 69.95  ? 544 GLU A C   1 
ATOM   4173  O  O   . GLU A 1 544 ? 199.636 178.184 177.149 1.00 68.27  ? 544 GLU A O   1 
ATOM   4174  C  CB  . GLU A 1 544 ? 198.200 177.018 179.702 1.00 68.62  ? 544 GLU A CB  1 
ATOM   4175  C  CG  . GLU A 1 544 ? 197.062 178.011 179.602 1.00 71.34  ? 544 GLU A CG  1 
ATOM   4176  C  CD  . GLU A 1 544 ? 197.108 179.051 180.694 1.00 75.63  ? 544 GLU A CD  1 
ATOM   4177  O  OE1 . GLU A 1 544 ? 197.838 178.838 181.682 1.00 75.06  ? 544 GLU A OE1 1 
ATOM   4178  O  OE2 . GLU A 1 544 ? 196.402 180.073 180.577 1.00 76.39  ? 544 GLU A OE2 1 
ATOM   4179  N  N   . MET A 1 545 ? 199.450 179.902 178.587 1.00 65.04  ? 545 MET A N   1 
ATOM   4180  C  CA  . MET A 1 545 ? 199.534 180.892 177.520 1.00 62.17  ? 545 MET A CA  1 
ATOM   4181  C  C   . MET A 1 545 ? 200.870 180.808 176.796 1.00 61.88  ? 545 MET A C   1 
ATOM   4182  O  O   . MET A 1 545 ? 200.918 180.713 175.563 1.00 65.86  ? 545 MET A O   1 
ATOM   4183  C  CB  . MET A 1 545 ? 199.316 182.294 178.083 1.00 62.35  ? 545 MET A CB  1 
ATOM   4184  C  CG  . MET A 1 545 ? 198.263 182.373 179.140 1.00 66.28  ? 545 MET A CG  1 
ATOM   4185  S  SD  . MET A 1 545 ? 196.617 182.261 178.423 1.00 84.68  ? 545 MET A SD  1 
ATOM   4186  C  CE  . MET A 1 545 ? 196.802 183.315 176.986 1.00 75.40  ? 545 MET A CE  1 
ATOM   4187  N  N   . VAL A 1 546 ? 201.974 180.852 177.545 1.00 56.61  ? 546 VAL A N   1 
ATOM   4188  C  CA  . VAL A 1 546 ? 203.269 180.794 176.892 1.00 55.09  ? 546 VAL A CA  1 
ATOM   4189  C  C   . VAL A 1 546 ? 203.457 179.443 176.233 1.00 59.45  ? 546 VAL A C   1 
ATOM   4190  O  O   . VAL A 1 546 ? 204.049 179.364 175.145 1.00 67.84  ? 546 VAL A O   1 
ATOM   4191  C  CB  . VAL A 1 546 ? 204.412 181.133 177.868 1.00 53.60  ? 546 VAL A CB  1 
ATOM   4192  C  CG1 . VAL A 1 546 ? 204.674 180.008 178.840 1.00 59.91  ? 546 VAL A CG1 1 
ATOM   4193  C  CG2 . VAL A 1 546 ? 205.667 181.444 177.103 1.00 52.74  ? 546 VAL A CG2 1 
ATOM   4194  N  N   . LYS A 1 547 ? 202.917 178.380 176.836 1.00 57.18  ? 547 LYS A N   1 
ATOM   4195  C  CA  . LYS A 1 547 ? 203.032 177.067 176.210 1.00 58.98  ? 547 LYS A CA  1 
ATOM   4196  C  C   . LYS A 1 547 ? 202.327 177.046 174.857 1.00 63.04  ? 547 LYS A C   1 
ATOM   4197  O  O   . LYS A 1 547 ? 202.856 176.496 173.884 1.00 61.51  ? 547 LYS A O   1 
ATOM   4198  C  CB  . LYS A 1 547 ? 202.480 175.994 177.145 1.00 59.01  ? 547 LYS A CB  1 
ATOM   4199  C  CG  . LYS A 1 547 ? 202.209 174.661 176.489 1.00 60.10  ? 547 LYS A CG  1 
ATOM   4200  C  CD  . LYS A 1 547 ? 201.198 173.865 177.289 1.00 64.16  ? 547 LYS A CD  1 
ATOM   4201  C  CE  . LYS A 1 547 ? 201.565 173.834 178.762 1.00 66.80  ? 547 LYS A CE  1 
ATOM   4202  N  NZ  . LYS A 1 547 ? 202.926 173.274 178.988 1.00 70.44  ? 547 LYS A NZ  1 
ATOM   4203  N  N   . GLU A 1 548 ? 201.144 177.664 174.777 1.00 68.32  ? 548 GLU A N   1 
ATOM   4204  C  CA  . GLU A 1 548 ? 200.446 177.824 173.502 1.00 68.56  ? 548 GLU A CA  1 
ATOM   4205  C  C   . GLU A 1 548 ? 201.303 178.596 172.511 1.00 59.55  ? 548 GLU A C   1 
ATOM   4206  O  O   . GLU A 1 548 ? 201.440 178.212 171.340 1.00 53.43  ? 548 GLU A O   1 
ATOM   4207  C  CB  . GLU A 1 548 ? 199.128 178.577 173.724 1.00 67.61  ? 548 GLU A CB  1 
ATOM   4208  C  CG  . GLU A 1 548 ? 198.096 177.882 174.579 1.00 66.63  ? 548 GLU A CG  1 
ATOM   4209  C  CD  . GLU A 1 548 ? 196.825 177.590 173.833 1.00 79.63  ? 548 GLU A CD  1 
ATOM   4210  O  OE1 . GLU A 1 548 ? 196.454 178.398 172.959 1.00 84.60  ? 548 GLU A OE1 1 
ATOM   4211  O  OE2 . GLU A 1 548 ? 196.191 176.554 174.123 1.00 85.93  ? 548 GLU A OE2 1 
ATOM   4212  N  N   . ARG A 1 549 ? 201.890 179.697 172.977 1.00 56.41  ? 549 ARG A N   1 
ATOM   4213  C  CA  . ARG A 1 549 ? 202.575 180.604 172.072 1.00 53.10  ? 549 ARG A CA  1 
ATOM   4214  C  C   . ARG A 1 549 ? 203.800 179.965 171.449 1.00 54.33  ? 549 ARG A C   1 
ATOM   4215  O  O   . ARG A 1 549 ? 204.141 180.292 170.309 1.00 59.25  ? 549 ARG A O   1 
ATOM   4216  C  CB  . ARG A 1 549 ? 202.971 181.888 172.791 1.00 56.52  ? 549 ARG A CB  1 
ATOM   4217  C  CG  . ARG A 1 549 ? 203.622 182.913 171.876 1.00 60.91  ? 549 ARG A CG  1 
ATOM   4218  C  CD  . ARG A 1 549 ? 203.776 184.247 172.559 1.00 61.51  ? 549 ARG A CD  1 
ATOM   4219  N  NE  . ARG A 1 549 ? 203.786 185.355 171.614 1.00 68.47  ? 549 ARG A NE  1 
ATOM   4220  C  CZ  . ARG A 1 549 ? 204.458 186.480 171.805 1.00 72.05  ? 549 ARG A CZ  1 
ATOM   4221  N  NH1 . ARG A 1 549 ? 205.183 186.674 172.891 1.00 71.63  ? 549 ARG A NH1 1 
ATOM   4222  N  NH2 . ARG A 1 549 ? 204.411 187.432 170.878 1.00 66.93  ? 549 ARG A NH2 1 
ATOM   4223  N  N   . LEU A 1 550 ? 204.497 179.078 172.162 1.00 52.41  ? 550 LEU A N   1 
ATOM   4224  C  CA  . LEU A 1 550 ? 205.668 178.483 171.516 1.00 58.52  ? 550 LEU A CA  1 
ATOM   4225  C  C   . LEU A 1 550 ? 205.266 177.721 170.258 1.00 65.56  ? 550 LEU A C   1 
ATOM   4226  O  O   . LEU A 1 550 ? 205.908 177.851 169.209 1.00 70.06  ? 550 LEU A O   1 
ATOM   4227  C  CB  . LEU A 1 550 ? 206.477 177.565 172.443 1.00 65.40  ? 550 LEU A CB  1 
ATOM   4228  C  CG  . LEU A 1 550 ? 207.118 177.905 173.801 1.00 76.77  ? 550 LEU A CG  1 
ATOM   4229  C  CD1 . LEU A 1 550 ? 207.719 179.323 173.833 1.00 70.88  ? 550 LEU A CD1 1 
ATOM   4230  C  CD2 . LEU A 1 550 ? 206.315 177.555 175.040 1.00 72.31  ? 550 LEU A CD2 1 
ATOM   4231  N  N   . VAL A 1 551 ? 204.195 176.932 170.332 1.00 65.14  ? 551 VAL A N   1 
ATOM   4232  C  CA  . VAL A 1 551 ? 203.793 176.168 169.157 1.00 63.28  ? 551 VAL A CA  1 
ATOM   4233  C  C   . VAL A 1 551 ? 203.163 177.078 168.111 1.00 61.47  ? 551 VAL A C   1 
ATOM   4234  O  O   . VAL A 1 551 ? 203.285 176.825 166.909 1.00 62.74  ? 551 VAL A O   1 
ATOM   4235  C  CB  . VAL A 1 551 ? 202.868 175.002 169.549 1.00 65.93  ? 551 VAL A CB  1 
ATOM   4236  C  CG1 . VAL A 1 551 ? 201.417 175.446 169.633 1.00 64.90  ? 551 VAL A CG1 1 
ATOM   4237  C  CG2 . VAL A 1 551 ? 203.031 173.863 168.559 1.00 63.45  ? 551 VAL A CG2 1 
ATOM   4238  N  N   . LEU A 1 552 ? 202.489 178.153 168.535 1.00 61.19  ? 552 LEU A N   1 
ATOM   4239  C  CA  . LEU A 1 552 ? 201.993 179.107 167.546 1.00 55.76  ? 552 LEU A CA  1 
ATOM   4240  C  C   . LEU A 1 552 ? 203.147 179.697 166.756 1.00 50.38  ? 552 LEU A C   1 
ATOM   4241  O  O   . LEU A 1 552 ? 203.075 179.826 165.531 1.00 51.70  ? 552 LEU A O   1 
ATOM   4242  C  CB  . LEU A 1 552 ? 201.187 180.220 168.215 1.00 56.94  ? 552 LEU A CB  1 
ATOM   4243  C  CG  . LEU A 1 552 ? 200.058 180.866 167.401 1.00 51.83  ? 552 LEU A CG  1 
ATOM   4244  C  CD1 . LEU A 1 552 ? 199.248 181.817 168.250 1.00 46.02  ? 552 LEU A CD1 1 
ATOM   4245  C  CD2 . LEU A 1 552 ? 200.573 181.585 166.179 1.00 50.42  ? 552 LEU A CD2 1 
ATOM   4246  N  N   . GLY A 1 553 ? 204.231 180.038 167.441 1.00 52.21  ? 553 GLY A N   1 
ATOM   4247  C  CA  . GLY A 1 553 ? 205.383 180.575 166.751 1.00 55.21  ? 553 GLY A CA  1 
ATOM   4248  C  C   . GLY A 1 553 ? 206.066 179.553 165.868 1.00 57.63  ? 553 GLY A C   1 
ATOM   4249  O  O   . GLY A 1 553 ? 206.566 179.885 164.791 1.00 61.14  ? 553 GLY A O   1 
ATOM   4250  N  N   . ALA A 1 554 ? 206.115 178.301 166.317 1.00 60.28  ? 554 ALA A N   1 
ATOM   4251  C  CA  . ALA A 1 554 ? 206.667 177.253 165.466 1.00 66.81  ? 554 ALA A CA  1 
ATOM   4252  C  C   . ALA A 1 554 ? 205.845 177.107 164.194 1.00 66.08  ? 554 ALA A C   1 
ATOM   4253  O  O   . ALA A 1 554 ? 206.397 176.977 163.095 1.00 69.00  ? 554 ALA A O   1 
ATOM   4254  C  CB  . ALA A 1 554 ? 206.724 175.929 166.226 1.00 67.84  ? 554 ALA A CB  1 
ATOM   4255  N  N   . ALA A 1 555 ? 204.521 177.142 164.326 1.00 64.76  ? 555 ALA A N   1 
ATOM   4256  C  CA  . ALA A 1 555 ? 203.658 177.079 163.156 1.00 60.93  ? 555 ALA A CA  1 
ATOM   4257  C  C   . ALA A 1 555 ? 203.880 178.276 162.248 1.00 57.95  ? 555 ALA A C   1 
ATOM   4258  O  O   . ALA A 1 555 ? 203.864 178.140 161.023 1.00 59.20  ? 555 ALA A O   1 
ATOM   4259  C  CB  . ALA A 1 555 ? 202.196 176.995 163.588 1.00 61.46  ? 555 ALA A CB  1 
ATOM   4260  N  N   . LEU A 1 556 ? 204.067 179.463 162.826 1.00 57.73  ? 556 LEU A N   1 
ATOM   4261  C  CA  . LEU A 1 556 ? 204.319 180.642 162.002 1.00 57.97  ? 556 LEU A CA  1 
ATOM   4262  C  C   . LEU A 1 556 ? 205.624 180.501 161.241 1.00 57.11  ? 556 LEU A C   1 
ATOM   4263  O  O   . LEU A 1 556 ? 205.719 180.900 160.077 1.00 59.99  ? 556 LEU A O   1 
ATOM   4264  C  CB  . LEU A 1 556 ? 204.333 181.906 162.863 1.00 56.82  ? 556 LEU A CB  1 
ATOM   4265  C  CG  . LEU A 1 556 ? 204.607 183.236 162.151 1.00 48.80  ? 556 LEU A CG  1 
ATOM   4266  C  CD1 . LEU A 1 556 ? 203.704 183.407 160.957 1.00 50.42  ? 556 LEU A CD1 1 
ATOM   4267  C  CD2 . LEU A 1 556 ? 204.418 184.386 163.100 1.00 49.23  ? 556 LEU A CD2 1 
ATOM   4268  N  N   . LYS A 1 557 ? 206.648 179.956 161.892 1.00 56.84  ? 557 LYS A N   1 
ATOM   4269  C  CA  . LYS A 1 557 ? 207.911 179.731 161.203 1.00 61.89  ? 557 LYS A CA  1 
ATOM   4270  C  C   . LYS A 1 557 ? 207.734 178.738 160.063 1.00 68.64  ? 557 LYS A C   1 
ATOM   4271  O  O   . LYS A 1 557 ? 208.256 178.944 158.959 1.00 71.36  ? 557 LYS A O   1 
ATOM   4272  C  CB  . LYS A 1 557 ? 208.965 179.239 162.190 1.00 61.00  ? 557 LYS A CB  1 
ATOM   4273  C  CG  . LYS A 1 557 ? 209.562 180.331 163.052 1.00 68.10  ? 557 LYS A CG  1 
ATOM   4274  C  CD  . LYS A 1 557 ? 210.634 179.779 163.977 1.00 71.53  ? 557 LYS A CD  1 
ATOM   4275  C  CE  . LYS A 1 557 ? 211.725 179.067 163.192 1.00 73.35  ? 557 LYS A CE  1 
ATOM   4276  N  NZ  . LYS A 1 557 ? 212.208 179.881 162.042 1.00 71.37  ? 557 LYS A NZ  1 
ATOM   4277  N  N   . GLU A 1 558 ? 206.978 177.664 160.305 1.00 69.82  ? 558 GLU A N   1 
ATOM   4278  C  CA  . GLU A 1 558 ? 206.701 176.703 159.242 1.00 68.22  ? 558 GLU A CA  1 
ATOM   4279  C  C   . GLU A 1 558 ? 205.941 177.356 158.099 1.00 66.86  ? 558 GLU A C   1 
ATOM   4280  O  O   . GLU A 1 558 ? 206.211 177.079 156.925 1.00 70.58  ? 558 GLU A O   1 
ATOM   4281  C  CB  . GLU A 1 558 ? 205.913 175.512 159.791 1.00 69.54  ? 558 GLU A CB  1 
ATOM   4282  C  CG  . GLU A 1 558 ? 206.583 174.724 160.917 1.00 75.07  ? 558 GLU A CG  1 
ATOM   4283  C  CD  . GLU A 1 558 ? 207.976 174.209 160.581 1.00 83.21  ? 558 GLU A CD  1 
ATOM   4284  O  OE1 . GLU A 1 558 ? 208.663 173.738 161.512 1.00 85.54  ? 558 GLU A OE1 1 
ATOM   4285  O  OE2 . GLU A 1 558 ? 208.376 174.224 159.398 1.00 85.26  ? 558 GLU A OE2 1 
ATOM   4286  N  N   . ALA A 1 559 ? 204.978 178.217 158.422 1.00 66.19  ? 559 ALA A N   1 
ATOM   4287  C  CA  . ALA A 1 559 ? 204.184 178.873 157.390 1.00 68.15  ? 559 ALA A CA  1 
ATOM   4288  C  C   . ALA A 1 559 ? 205.038 179.812 156.555 1.00 66.85  ? 559 ALA A C   1 
ATOM   4289  O  O   . ALA A 1 559 ? 204.883 179.881 155.332 1.00 67.38  ? 559 ALA A O   1 
ATOM   4290  C  CB  . ALA A 1 559 ? 203.016 179.629 158.021 1.00 66.67  ? 559 ALA A CB  1 
ATOM   4291  N  N   . ILE A 1 560 ? 205.936 180.551 157.199 1.00 61.09  ? 560 ILE A N   1 
ATOM   4292  C  CA  . ILE A 1 560 ? 206.851 181.403 156.455 1.00 57.60  ? 560 ILE A CA  1 
ATOM   4293  C  C   . ILE A 1 560 ? 207.730 180.556 155.552 1.00 62.60  ? 560 ILE A C   1 
ATOM   4294  O  O   . ILE A 1 560 ? 207.977 180.906 154.392 1.00 67.49  ? 560 ILE A O   1 
ATOM   4295  C  CB  . ILE A 1 560 ? 207.691 182.257 157.421 1.00 58.80  ? 560 ILE A CB  1 
ATOM   4296  C  CG1 . ILE A 1 560 ? 206.837 183.347 158.056 1.00 57.97  ? 560 ILE A CG1 1 
ATOM   4297  C  CG2 . ILE A 1 560 ? 208.847 182.896 156.690 1.00 64.74  ? 560 ILE A CG2 1 
ATOM   4298  C  CD1 . ILE A 1 560 ? 206.293 184.323 157.064 1.00 59.52  ? 560 ILE A CD1 1 
ATOM   4299  N  N   . SER A 1 561 ? 208.211 179.422 156.065 1.00 64.04  ? 561 SER A N   1 
ATOM   4300  C  CA  . SER A 1 561 ? 209.104 178.576 155.280 1.00 72.94  ? 561 SER A CA  1 
ATOM   4301  C  C   . SER A 1 561 ? 208.398 178.011 154.052 1.00 71.84  ? 561 SER A C   1 
ATOM   4302  O  O   . SER A 1 561 ? 208.911 178.098 152.931 1.00 68.76  ? 561 SER A O   1 
ATOM   4303  C  CB  . SER A 1 561 ? 209.654 177.450 156.155 1.00 75.68  ? 561 SER A CB  1 
ATOM   4304  O  OG  . SER A 1 561 ? 210.591 176.659 155.444 1.00 79.80  ? 561 SER A OG  1 
ATOM   4305  N  N   . ASN A 1 562 ? 207.207 177.450 154.239 1.00 71.54  ? 562 ASN A N   1 
ATOM   4306  C  CA  . ASN A 1 562 ? 206.485 176.823 153.140 1.00 70.69  ? 562 ASN A CA  1 
ATOM   4307  C  C   . ASN A 1 562 ? 205.712 177.821 152.293 1.00 72.61  ? 562 ASN A C   1 
ATOM   4308  O  O   . ASN A 1 562 ? 205.126 177.421 151.281 1.00 71.57  ? 562 ASN A O   1 
ATOM   4309  C  CB  . ASN A 1 562 ? 205.542 175.742 153.682 1.00 72.44  ? 562 ASN A CB  1 
ATOM   4310  C  CG  . ASN A 1 562 ? 204.116 176.239 153.880 1.00 73.02  ? 562 ASN A CG  1 
ATOM   4311  O  OD1 . ASN A 1 562 ? 203.331 176.326 152.938 1.00 68.03  ? 562 ASN A OD1 1 
ATOM   4312  N  ND2 . ASN A 1 562 ? 203.774 176.549 155.122 1.00 74.57  ? 562 ASN A ND2 1 
ATOM   4313  N  N   . ASN A 1 563 ? 205.711 179.100 152.672 1.00 75.40  ? 563 ASN A N   1 
ATOM   4314  C  CA  . ASN A 1 563 ? 205.000 180.155 151.950 1.00 73.28  ? 563 ASN A CA  1 
ATOM   4315  C  C   . ASN A 1 563 ? 203.494 179.886 151.943 1.00 63.52  ? 563 ASN A C   1 
ATOM   4316  O  O   . ASN A 1 563 ? 202.844 179.804 150.901 1.00 58.70  ? 563 ASN A O   1 
ATOM   4317  C  CB  . ASN A 1 563 ? 205.560 180.322 150.531 1.00 76.86  ? 563 ASN A CB  1 
ATOM   4318  C  CG  . ASN A 1 563 ? 207.083 180.265 150.492 1.00 75.29  ? 563 ASN A CG  1 
ATOM   4319  O  OD1 . ASN A 1 563 ? 207.763 181.246 150.788 1.00 67.29  ? 563 ASN A OD1 1 
ATOM   4320  N  ND2 . ASN A 1 563 ? 207.621 179.110 150.125 1.00 77.14  ? 563 ASN A ND2 1 
ATOM   4321  N  N   . GLN A 1 564 ? 202.946 179.762 153.146 1.00 62.13  ? 564 GLN A N   1 
ATOM   4322  C  CA  . GLN A 1 564 ? 201.521 179.527 153.314 1.00 66.34  ? 564 GLN A CA  1 
ATOM   4323  C  C   . GLN A 1 564 ? 200.713 180.807 153.462 1.00 64.98  ? 564 GLN A C   1 
ATOM   4324  O  O   . GLN A 1 564 ? 199.485 180.761 153.334 1.00 67.21  ? 564 GLN A O   1 
ATOM   4325  C  CB  . GLN A 1 564 ? 201.274 178.645 154.542 1.00 71.83  ? 564 GLN A CB  1 
ATOM   4326  C  CG  . GLN A 1 564 ? 199.925 177.943 154.552 1.00 71.55  ? 564 GLN A CG  1 
ATOM   4327  C  CD  . GLN A 1 564 ? 199.776 176.988 155.717 1.00 72.51  ? 564 GLN A CD  1 
ATOM   4328  O  OE1 . GLN A 1 564 ? 200.613 176.955 156.617 1.00 72.78  ? 564 GLN A OE1 1 
ATOM   4329  N  NE2 . GLN A 1 564 ? 198.704 176.205 155.708 1.00 73.80  ? 564 GLN A NE2 1 
ATOM   4330  N  N   . LEU A 1 565 ? 201.364 181.942 153.713 1.00 63.64  ? 565 LEU A N   1 
ATOM   4331  C  CA  . LEU A 1 565 ? 200.646 183.184 153.959 1.00 57.20  ? 565 LEU A CA  1 
ATOM   4332  C  C   . LEU A 1 565 ? 199.934 183.655 152.697 1.00 54.94  ? 565 LEU A C   1 
ATOM   4333  O  O   . LEU A 1 565 ? 199.969 183.014 151.644 1.00 61.36  ? 565 LEU A O   1 
ATOM   4334  C  CB  . LEU A 1 565 ? 201.593 184.280 154.429 1.00 50.90  ? 565 LEU A CB  1 
ATOM   4335  C  CG  . LEU A 1 565 ? 202.390 184.103 155.711 1.00 50.02  ? 565 LEU A CG  1 
ATOM   4336  C  CD1 . LEU A 1 565 ? 203.145 185.368 155.953 1.00 45.76  ? 565 LEU A CD1 1 
ATOM   4337  C  CD2 . LEU A 1 565 ? 201.481 183.798 156.866 1.00 52.06  ? 565 LEU A CD2 1 
ATOM   4338  N  N   . LYS A 1 566 ? 199.285 184.804 152.813 1.00 46.53  ? 566 LYS A N   1 
ATOM   4339  C  CA  . LYS A 1 566 ? 198.536 185.373 151.712 1.00 44.87  ? 566 LYS A CA  1 
ATOM   4340  C  C   . LYS A 1 566 ? 198.717 186.883 151.701 1.00 51.48  ? 566 LYS A C   1 
ATOM   4341  O  O   . LYS A 1 566 ? 199.038 187.499 152.719 1.00 56.88  ? 566 LYS A O   1 
ATOM   4342  C  CB  . LYS A 1 566 ? 197.055 185.011 151.813 1.00 49.51  ? 566 LYS A CB  1 
ATOM   4343  C  CG  . LYS A 1 566 ? 196.343 184.950 150.476 1.00 55.45  ? 566 LYS A CG  1 
ATOM   4344  C  CD  . LYS A 1 566 ? 194.874 184.598 150.643 1.00 59.67  ? 566 LYS A CD  1 
ATOM   4345  C  CE  . LYS A 1 566 ? 194.254 185.326 151.823 1.00 62.32  ? 566 LYS A CE  1 
ATOM   4346  N  NZ  . LYS A 1 566 ? 192.779 185.146 151.859 1.00 68.97  ? 566 LYS A NZ  1 
ATOM   4347  N  N   . LEU A 1 567 ? 198.514 187.473 150.524 1.00 52.55  ? 567 LEU A N   1 
ATOM   4348  C  CA  . LEU A 1 567 ? 198.598 188.915 150.323 1.00 45.98  ? 567 LEU A CA  1 
ATOM   4349  C  C   . LEU A 1 567 ? 197.269 189.399 149.764 1.00 43.24  ? 567 LEU A C   1 
ATOM   4350  O  O   . LEU A 1 567 ? 196.858 188.970 148.681 1.00 47.30  ? 567 LEU A O   1 
ATOM   4351  C  CB  . LEU A 1 567 ? 199.739 189.256 149.370 1.00 41.69  ? 567 LEU A CB  1 
ATOM   4352  C  CG  . LEU A 1 567 ? 200.585 190.469 149.716 1.00 40.04  ? 567 LEU A CG  1 
ATOM   4353  C  CD1 . LEU A 1 567 ? 200.916 190.440 151.165 1.00 39.83  ? 567 LEU A CD1 1 
ATOM   4354  C  CD2 . LEU A 1 567 ? 201.851 190.462 148.908 1.00 49.94  ? 567 LEU A CD2 1 
ATOM   4355  N  N   . VAL A 1 568 ? 196.605 190.295 150.485 1.00 38.52  ? 568 VAL A N   1 
ATOM   4356  C  CA  . VAL A 1 568 ? 195.274 190.761 150.126 1.00 40.92  ? 568 VAL A CA  1 
ATOM   4357  C  C   . VAL A 1 568 ? 195.365 192.236 149.764 1.00 49.94  ? 568 VAL A C   1 
ATOM   4358  O  O   . VAL A 1 568 ? 195.963 193.023 150.506 1.00 53.87  ? 568 VAL A O   1 
ATOM   4359  C  CB  . VAL A 1 568 ? 194.273 190.527 151.265 1.00 42.54  ? 568 VAL A CB  1 
ATOM   4360  C  CG1 . VAL A 1 568 ? 192.927 191.102 150.910 1.00 47.83  ? 568 VAL A CG1 1 
ATOM   4361  C  CG2 . VAL A 1 568 ? 194.152 189.044 151.543 1.00 47.90  ? 568 VAL A CG2 1 
ATOM   4362  N  N   . TYR A 1 569 ? 194.779 192.606 148.625 1.00 49.02  ? 569 TYR A N   1 
ATOM   4363  C  CA  . TYR A 1 569 ? 194.988 193.910 148.008 1.00 44.53  ? 569 TYR A CA  1 
ATOM   4364  C  C   . TYR A 1 569 ? 193.803 194.830 148.242 1.00 48.17  ? 569 TYR A C   1 
ATOM   4365  O  O   . TYR A 1 569 ? 192.662 194.467 147.946 1.00 49.03  ? 569 TYR A O   1 
ATOM   4366  C  CB  . TYR A 1 569 ? 195.242 193.759 146.513 1.00 36.52  ? 569 TYR A CB  1 
ATOM   4367  C  CG  . TYR A 1 569 ? 196.539 193.090 146.237 1.00 37.01  ? 569 TYR A CG  1 
ATOM   4368  C  CD1 . TYR A 1 569 ? 197.708 193.611 146.724 1.00 38.20  ? 569 TYR A CD1 1 
ATOM   4369  C  CD2 . TYR A 1 569 ? 196.598 191.940 145.488 1.00 42.35  ? 569 TYR A CD2 1 
ATOM   4370  C  CE1 . TYR A 1 569 ? 198.901 193.011 146.487 1.00 42.00  ? 569 TYR A CE1 1 
ATOM   4371  C  CE2 . TYR A 1 569 ? 197.793 191.325 145.236 1.00 47.92  ? 569 TYR A CE2 1 
ATOM   4372  C  CZ  . TYR A 1 569 ? 198.945 191.866 145.740 1.00 49.03  ? 569 TYR A CZ  1 
ATOM   4373  O  OH  . TYR A 1 569 ? 200.151 191.257 145.494 1.00 58.11  ? 569 TYR A OH  1 
ATOM   4374  N  N   . GLN A 1 570 ? 194.086 196.026 148.767 1.00 49.87  ? 570 GLN A N   1 
ATOM   4375  C  CA  . GLN A 1 570 ? 193.106 197.090 148.921 1.00 46.81  ? 570 GLN A CA  1 
ATOM   4376  C  C   . GLN A 1 570 ? 193.474 198.229 147.994 1.00 42.43  ? 570 GLN A C   1 
ATOM   4377  O  O   . GLN A 1 570 ? 194.637 198.653 147.982 1.00 43.56  ? 570 GLN A O   1 
ATOM   4378  C  CB  . GLN A 1 570 ? 193.036 197.595 150.350 1.00 46.95  ? 570 GLN A CB  1 
ATOM   4379  C  CG  . GLN A 1 570 ? 191.866 198.516 150.580 1.00 50.28  ? 570 GLN A CG  1 
ATOM   4380  C  CD  . GLN A 1 570 ? 191.923 199.198 151.925 1.00 57.77  ? 570 GLN A CD  1 
ATOM   4381  O  OE1 . GLN A 1 570 ? 193.002 199.486 152.440 1.00 58.68  ? 570 GLN A OE1 1 
ATOM   4382  N  NE2 . GLN A 1 570 ? 190.760 199.474 152.499 1.00 62.50  ? 570 GLN A NE2 1 
ATOM   4383  N  N   . PRO A 1 571 ? 192.545 198.727 147.194 1.00 43.70  ? 571 PRO A N   1 
ATOM   4384  C  CA  . PRO A 1 571 ? 192.857 199.794 146.248 1.00 52.34  ? 571 PRO A CA  1 
ATOM   4385  C  C   . PRO A 1 571 ? 192.590 201.173 146.843 1.00 59.82  ? 571 PRO A C   1 
ATOM   4386  O  O   . PRO A 1 571 ? 192.074 201.319 147.953 1.00 65.08  ? 571 PRO A O   1 
ATOM   4387  C  CB  . PRO A 1 571 ? 191.898 199.514 145.081 1.00 47.80  ? 571 PRO A CB  1 
ATOM   4388  C  CG  . PRO A 1 571 ? 191.068 198.322 145.495 1.00 48.43  ? 571 PRO A CG  1 
ATOM   4389  C  CD  . PRO A 1 571 ? 191.197 198.204 146.969 1.00 45.68  ? 571 PRO A CD  1 
ATOM   4390  N  N   . GLN A 1 572 ? 192.955 202.187 146.067 1.00 54.59  ? 572 GLN A N   1 
ATOM   4391  C  CA  . GLN A 1 572 ? 192.692 203.574 146.402 1.00 50.58  ? 572 GLN A CA  1 
ATOM   4392  C  C   . GLN A 1 572 ? 192.473 204.346 145.113 1.00 57.36  ? 572 GLN A C   1 
ATOM   4393  O  O   . GLN A 1 572 ? 193.198 204.154 144.136 1.00 61.33  ? 572 GLN A O   1 
ATOM   4394  C  CB  . GLN A 1 572 ? 193.835 204.143 147.221 1.00 45.03  ? 572 GLN A CB  1 
ATOM   4395  C  CG  . GLN A 1 572 ? 195.184 203.771 146.725 1.00 42.72  ? 572 GLN A CG  1 
ATOM   4396  C  CD  . GLN A 1 572 ? 196.178 203.779 147.841 1.00 45.63  ? 572 GLN A CD  1 
ATOM   4397  O  OE1 . GLN A 1 572 ? 195.795 203.777 149.002 1.00 50.26  ? 572 GLN A OE1 1 
ATOM   4398  N  NE2 . GLN A 1 572 ? 197.457 203.779 147.512 1.00 44.30  ? 572 GLN A NE2 1 
ATOM   4399  N  N   . ILE A 1 573 ? 191.446 205.195 145.099 1.00 55.63  ? 573 ILE A N   1 
ATOM   4400  C  CA  . ILE A 1 573 ? 190.977 205.829 143.876 1.00 56.19  ? 573 ILE A CA  1 
ATOM   4401  C  C   . ILE A 1 573 ? 190.826 207.330 144.103 1.00 64.50  ? 573 ILE A C   1 
ATOM   4402  O  O   . ILE A 1 573 ? 190.838 207.815 145.234 1.00 69.67  ? 573 ILE A O   1 
ATOM   4403  C  CB  . ILE A 1 573 ? 189.654 205.214 143.388 1.00 58.48  ? 573 ILE A CB  1 
ATOM   4404  C  CG1 . ILE A 1 573 ? 188.575 205.357 144.444 1.00 53.98  ? 573 ILE A CG1 1 
ATOM   4405  C  CG2 . ILE A 1 573 ? 189.836 203.749 143.045 1.00 64.25  ? 573 ILE A CG2 1 
ATOM   4406  C  CD1 . ILE A 1 573 ? 187.224 205.328 143.842 1.00 63.83  ? 573 ILE A CD1 1 
ATOM   4407  N  N   . PHE A 1 574 ? 190.683 208.065 142.998 1.00 65.23  ? 574 PHE A N   1 
ATOM   4408  C  CA  . PHE A 1 574 ? 190.649 209.521 143.035 1.00 62.11  ? 574 PHE A CA  1 
ATOM   4409  C  C   . PHE A 1 574 ? 189.317 210.032 143.584 1.00 67.78  ? 574 PHE A C   1 
ATOM   4410  O  O   . PHE A 1 574 ? 188.275 209.378 143.483 1.00 73.30  ? 574 PHE A O   1 
ATOM   4411  C  CB  . PHE A 1 574 ? 190.904 210.093 141.646 1.00 56.11  ? 574 PHE A CB  1 
ATOM   4412  C  CG  . PHE A 1 574 ? 192.311 209.920 141.179 1.00 50.04  ? 574 PHE A CG  1 
ATOM   4413  C  CD1 . PHE A 1 574 ? 193.274 210.840 141.498 1.00 49.99  ? 574 PHE A CD1 1 
ATOM   4414  C  CD2 . PHE A 1 574 ? 192.671 208.831 140.423 1.00 55.93  ? 574 PHE A CD2 1 
ATOM   4415  C  CE1 . PHE A 1 574 ? 194.569 210.684 141.076 1.00 48.96  ? 574 PHE A CE1 1 
ATOM   4416  C  CE2 . PHE A 1 574 ? 193.969 208.673 139.989 1.00 54.02  ? 574 PHE A CE2 1 
ATOM   4417  C  CZ  . PHE A 1 574 ? 194.919 209.606 140.319 1.00 46.93  ? 574 PHE A CZ  1 
ATOM   4418  N  N   . ALA A 1 575 ? 189.363 211.232 144.163 1.00 62.21  ? 575 ALA A N   1 
ATOM   4419  C  CA  . ALA A 1 575 ? 188.237 211.770 144.912 1.00 62.94  ? 575 ALA A CA  1 
ATOM   4420  C  C   . ALA A 1 575 ? 187.232 212.516 144.054 1.00 71.45  ? 575 ALA A C   1 
ATOM   4421  O  O   . ALA A 1 575 ? 186.121 212.780 144.522 1.00 74.68  ? 575 ALA A O   1 
ATOM   4422  C  CB  . ALA A 1 575 ? 188.736 212.708 146.011 1.00 64.34  ? 575 ALA A CB  1 
ATOM   4423  N  N   . GLU A 1 576 ? 187.592 212.891 142.831 1.00 76.33  ? 576 GLU A N   1 
ATOM   4424  C  CA  . GLU A 1 576 ? 186.638 213.565 141.963 1.00 76.37  ? 576 GLU A CA  1 
ATOM   4425  C  C   . GLU A 1 576 ? 186.626 212.951 140.570 1.00 77.62  ? 576 GLU A C   1 
ATOM   4426  O  O   . GLU A 1 576 ? 185.604 212.989 139.880 1.00 83.16  ? 576 GLU A O   1 
ATOM   4427  C  CB  . GLU A 1 576 ? 186.948 215.061 141.887 1.00 78.56  ? 576 GLU A CB  1 
ATOM   4428  C  CG  . GLU A 1 576 ? 188.029 215.436 140.887 1.00 81.68  ? 576 GLU A CG  1 
ATOM   4429  C  CD  . GLU A 1 576 ? 189.366 214.796 141.201 1.00 87.82  ? 576 GLU A CD  1 
ATOM   4430  O  OE1 . GLU A 1 576 ? 189.731 214.734 142.394 1.00 88.57  ? 576 GLU A OE1 1 
ATOM   4431  O  OE2 . GLU A 1 576 ? 190.048 214.347 140.257 1.00 87.35  ? 576 GLU A OE2 1 
ATOM   4432  N  N   . THR A 1 577 ? 187.754 212.378 140.149 1.00 77.21  ? 577 THR A N   1 
ATOM   4433  C  CA  . THR A 1 577 ? 187.823 211.768 138.828 1.00 78.70  ? 577 THR A CA  1 
ATOM   4434  C  C   . THR A 1 577 ? 187.094 210.433 138.784 1.00 79.69  ? 577 THR A C   1 
ATOM   4435  O  O   . THR A 1 577 ? 186.355 210.158 137.833 1.00 80.97  ? 577 THR A O   1 
ATOM   4436  C  CB  . THR A 1 577 ? 189.280 211.585 138.415 1.00 76.82  ? 577 THR A CB  1 
ATOM   4437  O  OG1 . THR A 1 577 ? 189.993 212.807 138.632 1.00 78.63  ? 577 THR A OG1 1 
ATOM   4438  C  CG2 . THR A 1 577 ? 189.373 211.200 136.950 1.00 72.59  ? 577 THR A CG2 1 
ATOM   4439  N  N   . GLY A 1 578 ? 187.277 209.601 139.805 1.00 79.10  ? 578 GLY A N   1 
ATOM   4440  C  CA  . GLY A 1 578 ? 186.701 208.274 139.844 1.00 79.73  ? 578 GLY A CA  1 
ATOM   4441  C  C   . GLY A 1 578 ? 187.638 207.155 139.436 1.00 76.18  ? 578 GLY A C   1 
ATOM   4442  O  O   . GLY A 1 578 ? 187.347 205.991 139.733 1.00 75.45  ? 578 GLY A O   1 
ATOM   4443  N  N   . GLU A 1 579 ? 188.751 207.468 138.782 1.00 71.50  ? 579 GLU A N   1 
ATOM   4444  C  CA  . GLU A 1 579 ? 189.700 206.452 138.367 1.00 64.22  ? 579 GLU A CA  1 
ATOM   4445  C  C   . GLU A 1 579 ? 190.497 205.939 139.559 1.00 61.55  ? 579 GLU A C   1 
ATOM   4446  O  O   . GLU A 1 579 ? 190.453 206.487 140.659 1.00 64.84  ? 579 GLU A O   1 
ATOM   4447  C  CB  . GLU A 1 579 ? 190.658 207.005 137.319 1.00 66.86  ? 579 GLU A CB  1 
ATOM   4448  C  CG  . GLU A 1 579 ? 189.998 207.525 136.072 1.00 75.19  ? 579 GLU A CG  1 
ATOM   4449  C  CD  . GLU A 1 579 ? 191.006 207.846 134.997 1.00 80.68  ? 579 GLU A CD  1 
ATOM   4450  O  OE1 . GLU A 1 579 ? 192.205 207.582 135.218 1.00 79.56  ? 579 GLU A OE1 1 
ATOM   4451  O  OE2 . GLU A 1 579 ? 190.604 208.360 133.932 1.00 84.23  ? 579 GLU A OE2 1 
ATOM   4452  N  N   . LEU A 1 580 ? 191.255 204.878 139.311 1.00 56.73  ? 580 LEU A N   1 
ATOM   4453  C  CA  . LEU A 1 580 ? 192.069 204.244 140.335 1.00 53.14  ? 580 LEU A CA  1 
ATOM   4454  C  C   . LEU A 1 580 ? 193.446 204.887 140.380 1.00 53.88  ? 580 LEU A C   1 
ATOM   4455  O  O   . LEU A 1 580 ? 194.102 205.029 139.345 1.00 58.75  ? 580 LEU A O   1 
ATOM   4456  C  CB  . LEU A 1 580 ? 192.190 202.753 140.038 1.00 54.88  ? 580 LEU A CB  1 
ATOM   4457  C  CG  . LEU A 1 580 ? 193.123 201.896 140.884 1.00 58.09  ? 580 LEU A CG  1 
ATOM   4458  C  CD1 . LEU A 1 580 ? 192.412 201.390 142.111 1.00 55.64  ? 580 LEU A CD1 1 
ATOM   4459  C  CD2 . LEU A 1 580 ? 193.630 200.741 140.055 1.00 60.76  ? 580 LEU A CD2 1 
ATOM   4460  N  N   . TYR A 1 581 ? 193.886 205.283 141.576 1.00 52.80  ? 581 TYR A N   1 
ATOM   4461  C  CA  . TYR A 1 581 ? 195.202 205.885 141.736 1.00 55.88  ? 581 TYR A CA  1 
ATOM   4462  C  C   . TYR A 1 581 ? 196.274 204.842 142.009 1.00 57.28  ? 581 TYR A C   1 
ATOM   4463  O  O   . TYR A 1 581 ? 197.415 204.992 141.563 1.00 56.89  ? 581 TYR A O   1 
ATOM   4464  C  CB  . TYR A 1 581 ? 195.165 206.930 142.859 1.00 54.54  ? 581 TYR A CB  1 
ATOM   4465  C  CG  . TYR A 1 581 ? 196.502 207.224 143.509 1.00 50.13  ? 581 TYR A CG  1 
ATOM   4466  C  CD1 . TYR A 1 581 ? 197.554 207.738 142.776 1.00 46.63  ? 581 TYR A CD1 1 
ATOM   4467  C  CD2 . TYR A 1 581 ? 196.698 207.012 144.861 1.00 49.48  ? 581 TYR A CD2 1 
ATOM   4468  C  CE1 . TYR A 1 581 ? 198.761 207.995 143.355 1.00 42.85  ? 581 TYR A CE1 1 
ATOM   4469  C  CE2 . TYR A 1 581 ? 197.907 207.280 145.449 1.00 48.96  ? 581 TYR A CE2 1 
ATOM   4470  C  CZ  . TYR A 1 581 ? 198.931 207.768 144.690 1.00 47.66  ? 581 TYR A CZ  1 
ATOM   4471  O  OH  . TYR A 1 581 ? 200.141 208.040 145.270 1.00 57.54  ? 581 TYR A OH  1 
ATOM   4472  N  N   . GLY A 1 582 ? 195.921 203.779 142.716 1.00 58.32  ? 582 GLY A N   1 
ATOM   4473  C  CA  . GLY A 1 582 ? 196.869 202.719 142.995 1.00 59.37  ? 582 GLY A CA  1 
ATOM   4474  C  C   . GLY A 1 582 ? 196.236 201.697 143.911 1.00 60.61  ? 582 GLY A C   1 
ATOM   4475  O  O   . GLY A 1 582 ? 195.038 201.757 144.199 1.00 62.13  ? 582 GLY A O   1 
ATOM   4476  N  N   . ILE A 1 583 ? 197.053 200.755 144.375 1.00 57.66  ? 583 ILE A N   1 
ATOM   4477  C  CA  . ILE A 1 583 ? 196.583 199.739 145.304 1.00 50.61  ? 583 ILE A CA  1 
ATOM   4478  C  C   . ILE A 1 583 ? 197.576 199.592 146.444 1.00 49.70  ? 583 ILE A C   1 
ATOM   4479  O  O   . ILE A 1 583 ? 198.783 199.780 146.271 1.00 52.88  ? 583 ILE A O   1 
ATOM   4480  C  CB  . ILE A 1 583 ? 196.354 198.386 144.612 1.00 45.23  ? 583 ILE A CB  1 
ATOM   4481  C  CG1 . ILE A 1 583 ? 197.560 198.025 143.760 1.00 51.19  ? 583 ILE A CG1 1 
ATOM   4482  C  CG2 . ILE A 1 583 ? 195.088 198.425 143.783 1.00 45.05  ? 583 ILE A CG2 1 
ATOM   4483  C  CD1 . ILE A 1 583 ? 197.581 196.584 143.337 1.00 53.07  ? 583 ILE A CD1 1 
ATOM   4484  N  N   . GLU A 1 584 ? 197.052 199.248 147.617 1.00 45.32  ? 584 GLU A N   1 
ATOM   4485  C  CA  . GLU A 1 584 ? 197.843 199.036 148.817 1.00 43.61  ? 584 GLU A CA  1 
ATOM   4486  C  C   . GLU A 1 584 ? 197.856 197.558 149.168 1.00 47.57  ? 584 GLU A C   1 
ATOM   4487  O  O   . GLU A 1 584 ? 196.813 196.899 149.158 1.00 50.94  ? 584 GLU A O   1 
ATOM   4488  C  CB  . GLU A 1 584 ? 197.290 199.833 149.992 1.00 45.94  ? 584 GLU A CB  1 
ATOM   4489  C  CG  . GLU A 1 584 ? 198.221 199.869 151.190 1.00 56.47  ? 584 GLU A CG  1 
ATOM   4490  C  CD  . GLU A 1 584 ? 197.475 199.815 152.512 1.00 63.85  ? 584 GLU A CD  1 
ATOM   4491  O  OE1 . GLU A 1 584 ? 198.136 199.809 153.572 1.00 67.35  ? 584 GLU A OE1 1 
ATOM   4492  O  OE2 . GLU A 1 584 ? 196.227 199.774 152.489 1.00 64.21  ? 584 GLU A OE2 1 
ATOM   4493  N  N   . ALA A 1 585 ? 199.039 197.043 149.485 1.00 47.72  ? 585 ALA A N   1 
ATOM   4494  C  CA  . ALA A 1 585 ? 199.243 195.629 149.753 1.00 41.14  ? 585 ALA A CA  1 
ATOM   4495  C  C   . ALA A 1 585 ? 199.228 195.364 151.250 1.00 38.27  ? 585 ALA A C   1 
ATOM   4496  O  O   . ALA A 1 585 ? 199.914 196.049 152.013 1.00 42.66  ? 585 ALA A O   1 
ATOM   4497  C  CB  . ALA A 1 585 ? 200.563 195.156 149.151 1.00 43.07  ? 585 ALA A CB  1 
ATOM   4498  N  N   . LEU A 1 586 ? 198.455 194.365 151.663 1.00 36.40  ? 586 LEU A N   1 
ATOM   4499  C  CA  . LEU A 1 586 ? 198.358 193.943 153.051 1.00 41.11  ? 586 LEU A CA  1 
ATOM   4500  C  C   . LEU A 1 586 ? 198.581 192.437 153.145 1.00 47.87  ? 586 LEU A C   1 
ATOM   4501  O  O   . LEU A 1 586 ? 198.189 191.692 152.242 1.00 50.37  ? 586 LEU A O   1 
ATOM   4502  C  CB  . LEU A 1 586 ? 196.999 194.295 153.629 1.00 40.32  ? 586 LEU A CB  1 
ATOM   4503  C  CG  . LEU A 1 586 ? 196.471 195.711 153.452 1.00 42.95  ? 586 LEU A CG  1 
ATOM   4504  C  CD1 . LEU A 1 586 ? 195.515 195.780 152.291 1.00 44.05  ? 586 LEU A CD1 1 
ATOM   4505  C  CD2 . LEU A 1 586 ? 195.783 196.147 154.721 1.00 47.14  ? 586 LEU A CD2 1 
ATOM   4506  N  N   . ALA A 1 587 ? 199.202 191.988 154.241 1.00 43.73  ? 587 ALA A N   1 
ATOM   4507  C  CA  . ALA A 1 587 ? 199.545 190.582 154.439 1.00 38.09  ? 587 ALA A CA  1 
ATOM   4508  C  C   . ALA A 1 587 ? 198.533 189.884 155.338 1.00 38.92  ? 587 ALA A C   1 
ATOM   4509  O  O   . ALA A 1 587 ? 197.889 190.511 156.179 1.00 41.15  ? 587 ALA A O   1 
ATOM   4510  C  CB  . ALA A 1 587 ? 200.943 190.452 155.031 1.00 34.70  ? 587 ALA A CB  1 
ATOM   4511  N  N   . ARG A 1 588 ? 198.406 188.567 155.162 1.00 39.16  ? 588 ARG A N   1 
ATOM   4512  C  CA  . ARG A 1 588 ? 197.357 187.803 155.830 1.00 43.40  ? 588 ARG A CA  1 
ATOM   4513  C  C   . ARG A 1 588 ? 197.831 186.380 156.097 1.00 49.92  ? 588 ARG A C   1 
ATOM   4514  O  O   . ARG A 1 588 ? 198.757 185.887 155.451 1.00 54.38  ? 588 ARG A O   1 
ATOM   4515  C  CB  . ARG A 1 588 ? 196.081 187.791 154.995 1.00 43.63  ? 588 ARG A CB  1 
ATOM   4516  C  CG  . ARG A 1 588 ? 194.817 187.700 155.814 1.00 49.39  ? 588 ARG A CG  1 
ATOM   4517  C  CD  . ARG A 1 588 ? 194.474 189.019 156.466 1.00 44.12  ? 588 ARG A CD  1 
ATOM   4518  N  NE  . ARG A 1 588 ? 194.372 190.101 155.502 1.00 39.99  ? 588 ARG A NE  1 
ATOM   4519  C  CZ  . ARG A 1 588 ? 194.293 191.381 155.829 1.00 44.46  ? 588 ARG A CZ  1 
ATOM   4520  N  NH1 . ARG A 1 588 ? 194.314 191.775 157.090 1.00 48.20  ? 588 ARG A NH1 1 
ATOM   4521  N  NH2 . ARG A 1 588 ? 194.185 192.290 154.867 1.00 46.50  ? 588 ARG A NH2 1 
ATOM   4522  N  N   . TRP A 1 589 ? 197.188 185.719 157.066 1.00 49.60  ? 589 TRP A N   1 
ATOM   4523  C  CA  . TRP A 1 589 ? 197.547 184.351 157.440 1.00 51.44  ? 589 TRP A CA  1 
ATOM   4524  C  C   . TRP A 1 589 ? 196.300 183.531 157.733 1.00 54.68  ? 589 TRP A C   1 
ATOM   4525  O  O   . TRP A 1 589 ? 195.517 183.865 158.634 1.00 57.41  ? 589 TRP A O   1 
ATOM   4526  C  CB  . TRP A 1 589 ? 198.491 184.324 158.650 1.00 56.68  ? 589 TRP A CB  1 
ATOM   4527  C  CG  . TRP A 1 589 ? 198.967 182.931 159.020 1.00 58.27  ? 589 TRP A CG  1 
ATOM   4528  C  CD1 . TRP A 1 589 ? 198.949 181.827 158.228 1.00 58.18  ? 589 TRP A CD1 1 
ATOM   4529  C  CD2 . TRP A 1 589 ? 199.506 182.503 160.283 1.00 53.94  ? 589 TRP A CD2 1 
ATOM   4530  N  NE1 . TRP A 1 589 ? 199.448 180.746 158.907 1.00 57.92  ? 589 TRP A NE1 1 
ATOM   4531  C  CE2 . TRP A 1 589 ? 199.787 181.135 160.173 1.00 55.51  ? 589 TRP A CE2 1 
ATOM   4532  C  CE3 . TRP A 1 589 ? 199.781 183.149 161.488 1.00 47.56  ? 589 TRP A CE3 1 
ATOM   4533  C  CZ2 . TRP A 1 589 ? 200.326 180.408 161.216 1.00 58.44  ? 589 TRP A CZ2 1 
ATOM   4534  C  CZ3 . TRP A 1 589 ? 200.293 182.429 162.518 1.00 46.53  ? 589 TRP A CZ3 1 
ATOM   4535  C  CH2 . TRP A 1 589 ? 200.572 181.073 162.381 1.00 54.63  ? 589 TRP A CH2 1 
ATOM   4536  N  N   . HIS A 1 590 ? 196.129 182.458 156.961 1.00 57.15  ? 590 HIS A N   1 
ATOM   4537  C  CA  . HIS A 1 590 ? 195.116 181.435 157.179 1.00 63.31  ? 590 HIS A CA  1 
ATOM   4538  C  C   . HIS A 1 590 ? 195.779 180.104 157.474 1.00 68.29  ? 590 HIS A C   1 
ATOM   4539  O  O   . HIS A 1 590 ? 196.622 179.644 156.699 1.00 70.00  ? 590 HIS A O   1 
ATOM   4540  C  CB  . HIS A 1 590 ? 194.202 181.280 155.969 1.00 65.48  ? 590 HIS A CB  1 
ATOM   4541  C  CG  . HIS A 1 590 ? 192.881 180.659 156.295 1.00 72.98  ? 590 HIS A CG  1 
ATOM   4542  N  ND1 . HIS A 1 590 ? 191.939 181.277 157.086 1.00 73.00  ? 590 HIS A ND1 1 
ATOM   4543  C  CD2 . HIS A 1 590 ? 192.347 179.468 155.936 1.00 77.33  ? 590 HIS A CD2 1 
ATOM   4544  C  CE1 . HIS A 1 590 ? 190.881 180.496 157.200 1.00 76.87  ? 590 HIS A CE1 1 
ATOM   4545  N  NE2 . HIS A 1 590 ? 191.102 179.392 156.510 1.00 79.63  ? 590 HIS A NE2 1 
ATOM   4546  N  N   . ASP A 1 591 ? 195.377 179.478 158.576 1.00 72.32  ? 591 ASP A N   1 
ATOM   4547  C  CA  . ASP A 1 591 ? 195.980 178.230 159.007 1.00 74.09  ? 591 ASP A CA  1 
ATOM   4548  C  C   . ASP A 1 591 ? 194.915 177.167 159.236 1.00 74.12  ? 591 ASP A C   1 
ATOM   4549  O  O   . ASP A 1 591 ? 193.812 177.479 159.698 1.00 76.04  ? 591 ASP A O   1 
ATOM   4550  C  CB  . ASP A 1 591 ? 196.788 178.443 160.291 1.00 68.66  ? 591 ASP A CB  1 
ATOM   4551  C  CG  . ASP A 1 591 ? 197.619 177.247 160.651 1.00 72.03  ? 591 ASP A CG  1 
ATOM   4552  O  OD1 . ASP A 1 591 ? 197.126 176.397 161.417 1.00 75.29  ? 591 ASP A OD1 1 
ATOM   4553  O  OD2 . ASP A 1 591 ? 198.756 177.145 160.152 1.00 72.14  ? 591 ASP A OD2 1 
ATOM   4554  N  N   . PRO A 1 592 ? 195.209 175.906 158.910 1.00 71.62  ? 592 PRO A N   1 
ATOM   4555  C  CA  . PRO A 1 592 ? 194.215 174.846 159.127 1.00 70.89  ? 592 PRO A CA  1 
ATOM   4556  C  C   . PRO A 1 592 ? 193.868 174.618 160.585 1.00 71.28  ? 592 PRO A C   1 
ATOM   4557  O  O   . PRO A 1 592 ? 192.809 174.048 160.874 1.00 71.74  ? 592 PRO A O   1 
ATOM   4558  C  CB  . PRO A 1 592 ? 194.883 173.614 158.506 1.00 71.74  ? 592 PRO A CB  1 
ATOM   4559  C  CG  . PRO A 1 592 ? 196.329 173.939 158.479 1.00 74.28  ? 592 PRO A CG  1 
ATOM   4560  C  CD  . PRO A 1 592 ? 196.401 175.399 158.217 1.00 72.32  ? 592 PRO A CD  1 
ATOM   4561  N  N   . LEU A 1 593 ? 194.722 175.036 161.517 1.00 71.72  ? 593 LEU A N   1 
ATOM   4562  C  CA  . LEU A 1 593 ? 194.430 174.857 162.934 1.00 73.14  ? 593 LEU A CA  1 
ATOM   4563  C  C   . LEU A 1 593 ? 193.827 176.108 163.563 1.00 75.92  ? 593 LEU A C   1 
ATOM   4564  O  O   . LEU A 1 593 ? 192.755 176.040 164.172 1.00 76.82  ? 593 LEU A O   1 
ATOM   4565  C  CB  . LEU A 1 593 ? 195.698 174.457 163.691 1.00 73.59  ? 593 LEU A CB  1 
ATOM   4566  C  CG  . LEU A 1 593 ? 195.953 172.962 163.880 1.00 77.39  ? 593 LEU A CG  1 
ATOM   4567  C  CD1 . LEU A 1 593 ? 195.019 172.401 164.940 1.00 77.99  ? 593 LEU A CD1 1 
ATOM   4568  C  CD2 . LEU A 1 593 ? 195.805 172.198 162.574 1.00 73.55  ? 593 LEU A CD2 1 
ATOM   4569  N  N   . HIS A 1 594 ? 194.497 177.253 163.426 1.00 75.64  ? 594 HIS A N   1 
ATOM   4570  C  CA  . HIS A 1 594 ? 194.077 178.471 164.103 1.00 73.37  ? 594 HIS A CA  1 
ATOM   4571  C  C   . HIS A 1 594 ? 193.194 179.370 163.248 1.00 73.24  ? 594 HIS A C   1 
ATOM   4572  O  O   . HIS A 1 594 ? 192.724 180.397 163.745 1.00 77.30  ? 594 HIS A O   1 
ATOM   4573  C  CB  . HIS A 1 594 ? 195.301 179.263 164.570 1.00 74.90  ? 594 HIS A CB  1 
ATOM   4574  C  CG  . HIS A 1 594 ? 196.467 178.407 164.957 1.00 74.41  ? 594 HIS A CG  1 
ATOM   4575  N  ND1 . HIS A 1 594 ? 197.628 178.356 164.217 1.00 72.41  ? 594 HIS A ND1 1 
ATOM   4576  C  CD2 . HIS A 1 594 ? 196.647 177.560 165.996 1.00 70.98  ? 594 HIS A CD2 1 
ATOM   4577  C  CE1 . HIS A 1 594 ? 198.476 177.520 164.789 1.00 69.01  ? 594 HIS A CE1 1 
ATOM   4578  N  NE2 . HIS A 1 594 ? 197.905 177.024 165.870 1.00 70.63  ? 594 HIS A NE2 1 
ATOM   4579  N  N   . GLY A 1 595 ? 192.955 179.017 161.989 1.00 73.43  ? 595 GLY A N   1 
ATOM   4580  C  CA  . GLY A 1 595 ? 192.057 179.781 161.143 1.00 75.13  ? 595 GLY A CA  1 
ATOM   4581  C  C   . GLY A 1 595 ? 192.598 181.120 160.686 1.00 73.13  ? 595 GLY A C   1 
ATOM   4582  O  O   . GLY A 1 595 ? 193.750 181.208 160.256 1.00 71.26  ? 595 GLY A O   1 
ATOM   4583  N  N   . HIS A 1 596 ? 191.755 182.150 160.719 1.00 71.83  ? 596 HIS A N   1 
ATOM   4584  C  CA  . HIS A 1 596 ? 192.206 183.509 160.455 1.00 64.33  ? 596 HIS A CA  1 
ATOM   4585  C  C   . HIS A 1 596 ? 193.075 184.000 161.598 1.00 64.56  ? 596 HIS A C   1 
ATOM   4586  O  O   . HIS A 1 596 ? 192.727 183.836 162.771 1.00 68.60  ? 596 HIS A O   1 
ATOM   4587  C  CB  . HIS A 1 596 ? 191.014 184.452 160.299 1.00 66.54  ? 596 HIS A CB  1 
ATOM   4588  C  CG  . HIS A 1 596 ? 190.158 184.172 159.106 1.00 79.12  ? 596 HIS A CG  1 
ATOM   4589  N  ND1 . HIS A 1 596 ? 190.619 183.493 158.001 1.00 77.69  ? 596 HIS A ND1 1 
ATOM   4590  C  CD2 . HIS A 1 596 ? 188.866 184.481 158.845 1.00 86.35  ? 596 HIS A CD2 1 
ATOM   4591  C  CE1 . HIS A 1 596 ? 189.650 183.398 157.109 1.00 80.97  ? 596 HIS A CE1 1 
ATOM   4592  N  NE2 . HIS A 1 596 ? 188.574 183.987 157.598 1.00 88.38  ? 596 HIS A NE2 1 
ATOM   4593  N  N   . VAL A 1 597 ? 194.200 184.627 161.265 1.00 60.51  ? 597 VAL A N   1 
ATOM   4594  C  CA  . VAL A 1 597 ? 195.002 185.279 162.300 1.00 53.44  ? 597 VAL A CA  1 
ATOM   4595  C  C   . VAL A 1 597 ? 195.481 186.638 161.807 1.00 51.86  ? 597 VAL A C   1 
ATOM   4596  O  O   . VAL A 1 597 ? 196.209 186.722 160.809 1.00 54.15  ? 597 VAL A O   1 
ATOM   4597  C  CB  . VAL A 1 597 ? 196.160 184.378 162.733 1.00 50.91  ? 597 VAL A CB  1 
ATOM   4598  C  CG1 . VAL A 1 597 ? 195.665 183.301 163.662 1.00 55.41  ? 597 VAL A CG1 1 
ATOM   4599  C  CG2 . VAL A 1 597 ? 196.654 183.697 161.539 1.00 54.25  ? 597 VAL A CG2 1 
ATOM   4600  N  N   . PRO A 1 598 ? 195.096 187.720 162.472 1.00 50.24  ? 598 PRO A N   1 
ATOM   4601  C  CA  . PRO A 1 598 ? 195.274 189.052 161.901 1.00 49.39  ? 598 PRO A CA  1 
ATOM   4602  C  C   . PRO A 1 598 ? 196.711 189.522 162.008 1.00 51.10  ? 598 PRO A C   1 
ATOM   4603  O  O   . PRO A 1 598 ? 197.470 189.042 162.863 1.00 56.20  ? 598 PRO A O   1 
ATOM   4604  C  CB  . PRO A 1 598 ? 194.340 189.919 162.752 1.00 48.55  ? 598 PRO A CB  1 
ATOM   4605  C  CG  . PRO A 1 598 ? 194.287 189.221 164.057 1.00 51.68  ? 598 PRO A CG  1 
ATOM   4606  C  CD  . PRO A 1 598 ? 194.413 187.755 163.772 1.00 48.13  ? 598 PRO A CD  1 
ATOM   4607  N  N   . PRO A 1 599 ? 197.121 190.465 161.157 1.00 45.80  ? 599 PRO A N   1 
ATOM   4608  C  CA  . PRO A 1 599 ? 198.483 191.008 161.265 1.00 44.75  ? 599 PRO A CA  1 
ATOM   4609  C  C   . PRO A 1 599 ? 198.773 191.661 162.600 1.00 46.13  ? 599 PRO A C   1 
ATOM   4610  O  O   . PRO A 1 599 ? 199.906 191.567 163.092 1.00 50.45  ? 599 PRO A O   1 
ATOM   4611  C  CB  . PRO A 1 599 ? 198.549 192.019 160.115 1.00 44.35  ? 599 PRO A CB  1 
ATOM   4612  C  CG  . PRO A 1 599 ? 197.136 192.307 159.770 1.00 46.82  ? 599 PRO A CG  1 
ATOM   4613  C  CD  . PRO A 1 599 ? 196.386 191.050 160.028 1.00 47.67  ? 599 PRO A CD  1 
ATOM   4614  N  N   . SER A 1 600 ? 197.785 192.295 163.210 1.00 43.43  ? 600 SER A N   1 
ATOM   4615  C  CA  . SER A 1 600 ? 197.920 192.893 164.530 1.00 43.52  ? 600 SER A CA  1 
ATOM   4616  C  C   . SER A 1 600 ? 198.075 191.887 165.599 1.00 46.39  ? 600 SER A C   1 
ATOM   4617  O  O   . SER A 1 600 ? 198.033 192.256 166.775 1.00 47.79  ? 600 SER A O   1 
ATOM   4618  C  CB  . SER A 1 600 ? 196.714 193.775 164.841 1.00 44.42  ? 600 SER A CB  1 
ATOM   4619  O  OG  . SER A 1 600 ? 195.580 192.989 165.150 1.00 46.25  ? 600 SER A OG  1 
ATOM   4620  N  N   . ARG A 1 601 ? 198.212 190.610 165.259 1.00 45.50  ? 601 ARG A N   1 
ATOM   4621  C  CA  . ARG A 1 601 ? 198.508 189.589 166.242 1.00 45.40  ? 601 ARG A CA  1 
ATOM   4622  C  C   . ARG A 1 601 ? 199.646 188.674 165.831 1.00 42.53  ? 601 ARG A C   1 
ATOM   4623  O  O   . ARG A 1 601 ? 200.131 187.918 166.676 1.00 46.88  ? 601 ARG A O   1 
ATOM   4624  C  CB  . ARG A 1 601 ? 197.259 188.746 166.543 1.00 52.36  ? 601 ARG A CB  1 
ATOM   4625  C  CG  . ARG A 1 601 ? 197.323 188.001 167.868 1.00 53.45  ? 601 ARG A CG  1 
ATOM   4626  C  CD  . ARG A 1 601 ? 195.983 187.423 168.301 1.00 54.89  ? 601 ARG A CD  1 
ATOM   4627  N  NE  . ARG A 1 601 ? 195.841 186.014 167.956 1.00 62.63  ? 601 ARG A NE  1 
ATOM   4628  C  CZ  . ARG A 1 601 ? 194.931 185.534 167.119 1.00 66.03  ? 601 ARG A CZ  1 
ATOM   4629  N  NH1 . ARG A 1 601 ? 194.025 186.319 166.562 1.00 64.67  ? 601 ARG A NH1 1 
ATOM   4630  N  NH2 . ARG A 1 601 ? 194.918 184.232 166.850 1.00 66.52  ? 601 ARG A NH2 1 
ATOM   4631  N  N   . PHE A 1 602 ? 200.090 188.705 164.578 1.00 40.75  ? 602 PHE A N   1 
ATOM   4632  C  CA  . PHE A 1 602 ? 201.245 187.910 164.195 1.00 45.95  ? 602 PHE A CA  1 
ATOM   4633  C  C   . PHE A 1 602 ? 202.456 188.731 163.773 1.00 51.35  ? 602 PHE A C   1 
ATOM   4634  O  O   . PHE A 1 602 ? 203.510 188.145 163.508 1.00 57.01  ? 602 PHE A O   1 
ATOM   4635  C  CB  . PHE A 1 602 ? 200.868 186.893 163.104 1.00 44.04  ? 602 PHE A CB  1 
ATOM   4636  C  CG  . PHE A 1 602 ? 200.944 187.402 161.693 1.00 42.81  ? 602 PHE A CG  1 
ATOM   4637  C  CD1 . PHE A 1 602 ? 202.127 187.374 160.985 1.00 43.40  ? 602 PHE A CD1 1 
ATOM   4638  C  CD2 . PHE A 1 602 ? 199.805 187.796 161.038 1.00 43.78  ? 602 PHE A CD2 1 
ATOM   4639  C  CE1 . PHE A 1 602 ? 202.179 187.802 159.690 1.00 44.63  ? 602 PHE A CE1 1 
ATOM   4640  C  CE2 . PHE A 1 602 ? 199.856 188.210 159.740 1.00 43.61  ? 602 PHE A CE2 1 
ATOM   4641  C  CZ  . PHE A 1 602 ? 201.045 188.219 159.068 1.00 44.37  ? 602 PHE A CZ  1 
ATOM   4642  N  N   . ILE A 1 603 ? 202.359 190.054 163.726 1.00 46.58  ? 603 ILE A N   1 
ATOM   4643  C  CA  . ILE A 1 603 ? 203.562 190.869 163.569 1.00 43.90  ? 603 ILE A CA  1 
ATOM   4644  C  C   . ILE A 1 603 ? 204.262 191.014 164.918 1.00 51.83  ? 603 ILE A C   1 
ATOM   4645  O  O   . ILE A 1 603 ? 205.493 190.888 164.972 1.00 60.74  ? 603 ILE A O   1 
ATOM   4646  C  CB  . ILE A 1 603 ? 203.243 192.229 162.937 1.00 46.34  ? 603 ILE A CB  1 
ATOM   4647  C  CG1 . ILE A 1 603 ? 203.298 192.119 161.417 1.00 49.76  ? 603 ILE A CG1 1 
ATOM   4648  C  CG2 . ILE A 1 603 ? 204.216 193.291 163.422 1.00 52.80  ? 603 ILE A CG2 1 
ATOM   4649  C  CD1 . ILE A 1 603 ? 204.650 191.782 160.903 1.00 49.35  ? 603 ILE A CD1 1 
ATOM   4650  N  N   . PRO A 1 604 ? 203.557 191.276 166.027 1.00 49.90  ? 604 PRO A N   1 
ATOM   4651  C  CA  . PRO A 1 604 ? 204.225 191.146 167.331 1.00 53.34  ? 604 PRO A CA  1 
ATOM   4652  C  C   . PRO A 1 604 ? 204.794 189.760 167.577 1.00 56.08  ? 604 PRO A C   1 
ATOM   4653  O  O   . PRO A 1 604 ? 205.891 189.630 168.139 1.00 60.32  ? 604 PRO A O   1 
ATOM   4654  C  CB  . PRO A 1 604 ? 203.111 191.486 168.326 1.00 48.99  ? 604 PRO A CB  1 
ATOM   4655  C  CG  . PRO A 1 604 ? 202.185 192.311 167.578 1.00 44.39  ? 604 PRO A CG  1 
ATOM   4656  C  CD  . PRO A 1 604 ? 202.188 191.791 166.188 1.00 46.71  ? 604 PRO A CD  1 
ATOM   4657  N  N   . LEU A 1 605 ? 204.083 188.713 167.159 1.00 53.23  ? 605 LEU A N   1 
ATOM   4658  C  CA  . LEU A 1 605 ? 204.616 187.366 167.313 1.00 54.26  ? 605 LEU A CA  1 
ATOM   4659  C  C   . LEU A 1 605 ? 205.861 187.176 166.467 1.00 54.22  ? 605 LEU A C   1 
ATOM   4660  O  O   . LEU A 1 605 ? 206.823 186.534 166.901 1.00 61.03  ? 605 LEU A O   1 
ATOM   4661  C  CB  . LEU A 1 605 ? 203.562 186.329 166.947 1.00 54.65  ? 605 LEU A CB  1 
ATOM   4662  C  CG  . LEU A 1 605 ? 202.884 185.639 168.126 1.00 58.82  ? 605 LEU A CG  1 
ATOM   4663  C  CD1 . LEU A 1 605 ? 202.061 186.628 168.923 1.00 54.91  ? 605 LEU A CD1 1 
ATOM   4664  C  CD2 . LEU A 1 605 ? 202.023 184.496 167.652 1.00 61.60  ? 605 LEU A CD2 1 
ATOM   4665  N  N   . ALA A 1 606 ? 205.861 187.714 165.249 1.00 50.23  ? 606 ALA A N   1 
ATOM   4666  C  CA  . ALA A 1 606 ? 207.055 187.632 164.424 1.00 56.50  ? 606 ALA A CA  1 
ATOM   4667  C  C   . ALA A 1 606 ? 208.206 188.387 165.060 1.00 65.42  ? 606 ALA A C   1 
ATOM   4668  O  O   . ALA A 1 606 ? 209.366 187.983 164.930 1.00 71.91  ? 606 ALA A O   1 
ATOM   4669  C  CB  . ALA A 1 606 ? 206.771 188.172 163.025 1.00 57.08  ? 606 ALA A CB  1 
ATOM   4670  N  N   . GLU A 1 607 ? 207.900 189.485 165.748 1.00 62.71  ? 607 GLU A N   1 
ATOM   4671  C  CA  . GLU A 1 607 ? 208.924 190.210 166.485 1.00 61.85  ? 607 GLU A CA  1 
ATOM   4672  C  C   . GLU A 1 607 ? 209.519 189.347 167.585 1.00 65.80  ? 607 GLU A C   1 
ATOM   4673  O  O   . GLU A 1 607 ? 210.742 189.301 167.755 1.00 67.34  ? 607 GLU A O   1 
ATOM   4674  C  CB  . GLU A 1 607 ? 208.320 191.481 167.078 1.00 63.37  ? 607 GLU A CB  1 
ATOM   4675  C  CG  . GLU A 1 607 ? 208.770 192.825 166.494 1.00 73.43  ? 607 GLU A CG  1 
ATOM   4676  C  CD  . GLU A 1 607 ? 210.276 193.017 166.306 1.00 84.08  ? 607 GLU A CD  1 
ATOM   4677  O  OE1 . GLU A 1 607 ? 211.091 192.112 166.585 1.00 84.65  ? 607 GLU A OE1 1 
ATOM   4678  O  OE2 . GLU A 1 607 ? 210.649 194.126 165.873 1.00 87.01  ? 607 GLU A OE2 1 
ATOM   4679  N  N   . GLU A 1 608 ? 208.671 188.638 168.332 1.00 69.89  ? 608 GLU A N   1 
ATOM   4680  C  CA  . GLU A 1 608 ? 209.171 187.900 169.488 1.00 70.53  ? 608 GLU A CA  1 
ATOM   4681  C  C   . GLU A 1 608 ? 210.043 186.724 169.064 1.00 69.66  ? 608 GLU A C   1 
ATOM   4682  O  O   . GLU A 1 608 ? 210.940 186.320 169.811 1.00 71.67  ? 608 GLU A O   1 
ATOM   4683  C  CB  . GLU A 1 608 ? 207.989 187.474 170.374 1.00 66.34  ? 608 GLU A CB  1 
ATOM   4684  C  CG  . GLU A 1 608 ? 208.245 186.431 171.473 1.00 69.01  ? 608 GLU A CG  1 
ATOM   4685  C  CD  . GLU A 1 608 ? 208.491 185.022 170.968 1.00 75.83  ? 608 GLU A CD  1 
ATOM   4686  O  OE1 . GLU A 1 608 ? 208.070 184.715 169.838 1.00 69.46  ? 608 GLU A OE1 1 
ATOM   4687  O  OE2 . GLU A 1 608 ? 209.108 184.224 171.705 1.00 85.25  ? 608 GLU A OE2 1 
ATOM   4688  N  N   . ILE A 1 609 ? 209.821 186.180 167.870 1.00 64.53  ? 609 ILE A N   1 
ATOM   4689  C  CA  . ILE A 1 609 ? 210.663 185.111 167.347 1.00 63.40  ? 609 ILE A CA  1 
ATOM   4690  C  C   . ILE A 1 609 ? 211.862 185.732 166.651 1.00 66.53  ? 609 ILE A C   1 
ATOM   4691  O  O   . ILE A 1 609 ? 212.857 185.056 166.374 1.00 68.68  ? 609 ILE A O   1 
ATOM   4692  C  CB  . ILE A 1 609 ? 209.891 184.206 166.375 1.00 65.50  ? 609 ILE A CB  1 
ATOM   4693  C  CG1 . ILE A 1 609 ? 208.555 183.800 166.972 1.00 64.07  ? 609 ILE A CG1 1 
ATOM   4694  C  CG2 . ILE A 1 609 ? 210.702 182.960 166.040 1.00 71.54  ? 609 ILE A CG2 1 
ATOM   4695  C  CD1 . ILE A 1 609 ? 208.027 182.557 166.384 1.00 64.41  ? 609 ILE A CD1 1 
ATOM   4696  N  N   . GLY A 1 610 ? 211.786 187.027 166.376 1.00 68.31  ? 610 GLY A N   1 
ATOM   4697  C  CA  . GLY A 1 610 ? 212.825 187.671 165.599 1.00 71.64  ? 610 GLY A CA  1 
ATOM   4698  C  C   . GLY A 1 610 ? 212.855 187.188 164.164 1.00 75.67  ? 610 GLY A C   1 
ATOM   4699  O  O   . GLY A 1 610 ? 213.923 186.928 163.604 1.00 80.39  ? 610 GLY A O   1 
ATOM   4700  N  N   . GLU A 1 611 ? 211.675 187.059 163.563 1.00 70.97  ? 611 GLU A N   1 
ATOM   4701  C  CA  . GLU A 1 611 ? 211.526 186.664 162.170 1.00 67.89  ? 611 GLU A CA  1 
ATOM   4702  C  C   . GLU A 1 611 ? 210.923 187.788 161.339 1.00 67.43  ? 611 GLU A C   1 
ATOM   4703  O  O   . GLU A 1 611 ? 210.319 187.540 160.296 1.00 74.57  ? 611 GLU A O   1 
ATOM   4704  C  CB  . GLU A 1 611 ? 210.669 185.407 162.058 1.00 69.35  ? 611 GLU A CB  1 
ATOM   4705  C  CG  . GLU A 1 611 ? 211.367 184.140 162.492 1.00 75.17  ? 611 GLU A CG  1 
ATOM   4706  C  CD  . GLU A 1 611 ? 211.917 183.359 161.322 1.00 83.46  ? 611 GLU A CD  1 
ATOM   4707  O  OE1 . GLU A 1 611 ? 212.456 183.991 160.391 1.00 87.40  ? 611 GLU A OE1 1 
ATOM   4708  O  OE2 . GLU A 1 611 ? 211.809 182.114 161.328 1.00 82.24  ? 611 GLU A OE2 1 
ATOM   4709  N  N   . ILE A 1 612 ? 211.071 189.030 161.797 1.00 60.34  ? 612 ILE A N   1 
ATOM   4710  C  CA  . ILE A 1 612 ? 210.471 190.157 161.092 1.00 63.94  ? 612 ILE A CA  1 
ATOM   4711  C  C   . ILE A 1 612 ? 211.122 190.340 159.728 1.00 68.01  ? 612 ILE A C   1 
ATOM   4712  O  O   . ILE A 1 612 ? 210.453 190.689 158.744 1.00 71.47  ? 612 ILE A O   1 
ATOM   4713  C  CB  . ILE A 1 612 ? 210.563 191.426 161.955 1.00 72.66  ? 612 ILE A CB  1 
ATOM   4714  C  CG1 . ILE A 1 612 ? 209.328 191.537 162.844 1.00 69.56  ? 612 ILE A CG1 1 
ATOM   4715  C  CG2 . ILE A 1 612 ? 210.704 192.673 161.092 1.00 72.45  ? 612 ILE A CG2 1 
ATOM   4716  C  CD1 . ILE A 1 612 ? 208.068 191.795 162.072 1.00 62.81  ? 612 ILE A CD1 1 
ATOM   4717  N  N   . GLU A 1 613 ? 212.428 190.089 159.638 1.00 70.75  ? 613 GLU A N   1 
ATOM   4718  C  CA  . GLU A 1 613 ? 213.108 190.207 158.355 1.00 75.62  ? 613 GLU A CA  1 
ATOM   4719  C  C   . GLU A 1 613 ? 212.515 189.253 157.328 1.00 75.36  ? 613 GLU A C   1 
ATOM   4720  O  O   . GLU A 1 613 ? 212.310 189.628 156.167 1.00 77.30  ? 613 GLU A O   1 
ATOM   4721  C  CB  . GLU A 1 613 ? 214.604 189.945 158.522 1.00 79.18  ? 613 GLU A CB  1 
ATOM   4722  C  CG  . GLU A 1 613 ? 215.277 190.807 159.576 1.00 85.42  ? 613 GLU A CG  1 
ATOM   4723  C  CD  . GLU A 1 613 ? 216.769 190.552 159.672 1.00 93.30  ? 613 GLU A CD  1 
ATOM   4724  O  OE1 . GLU A 1 613 ? 217.206 189.429 159.343 1.00 94.77  ? 613 GLU A OE1 1 
ATOM   4725  O  OE2 . GLU A 1 613 ? 217.507 191.477 160.074 1.00 94.73  ? 613 GLU A OE2 1 
ATOM   4726  N  N   . ASN A 1 614 ? 212.216 188.019 157.739 1.00 70.99  ? 614 ASN A N   1 
ATOM   4727  C  CA  . ASN A 1 614 ? 211.713 187.030 156.791 1.00 71.50  ? 614 ASN A CA  1 
ATOM   4728  C  C   . ASN A 1 614 ? 210.322 187.390 156.282 1.00 68.47  ? 614 ASN A C   1 
ATOM   4729  O  O   . ASN A 1 614 ? 210.050 187.274 155.081 1.00 71.81  ? 614 ASN A O   1 
ATOM   4730  C  CB  . ASN A 1 614 ? 211.716 185.647 157.430 1.00 75.43  ? 614 ASN A CB  1 
ATOM   4731  C  CG  . ASN A 1 614 ? 213.063 184.971 157.330 1.00 81.26  ? 614 ASN A CG  1 
ATOM   4732  O  OD1 . ASN A 1 614 ? 213.633 184.856 156.248 1.00 81.09  ? 614 ASN A OD1 1 
ATOM   4733  N  ND2 . ASN A 1 614 ? 213.583 184.520 158.464 1.00 86.00  ? 614 ASN A ND2 1 
ATOM   4734  N  N   . ILE A 1 615 ? 209.425 187.828 157.167 1.00 61.19  ? 615 ILE A N   1 
ATOM   4735  C  CA  . ILE A 1 615 ? 208.090 188.198 156.712 1.00 56.01  ? 615 ILE A CA  1 
ATOM   4736  C  C   . ILE A 1 615 ? 208.151 189.438 155.834 1.00 59.99  ? 615 ILE A C   1 
ATOM   4737  O  O   . ILE A 1 615 ? 207.423 189.545 154.837 1.00 64.63  ? 615 ILE A O   1 
ATOM   4738  C  CB  . ILE A 1 615 ? 207.136 188.384 157.902 1.00 50.56  ? 615 ILE A CB  1 
ATOM   4739  C  CG1 . ILE A 1 615 ? 205.874 189.127 157.469 1.00 48.29  ? 615 ILE A CG1 1 
ATOM   4740  C  CG2 . ILE A 1 615 ? 207.809 189.116 159.018 1.00 62.20  ? 615 ILE A CG2 1 
ATOM   4741  C  CD1 . ILE A 1 615 ? 205.014 188.380 156.511 1.00 54.64  ? 615 ILE A CD1 1 
ATOM   4742  N  N   . GLY A 1 616 ? 209.022 190.390 156.172 1.00 60.27  ? 616 GLY A N   1 
ATOM   4743  C  CA  . GLY A 1 616 ? 209.172 191.551 155.310 1.00 63.37  ? 616 GLY A CA  1 
ATOM   4744  C  C   . GLY A 1 616 ? 209.656 191.167 153.927 1.00 64.83  ? 616 GLY A C   1 
ATOM   4745  O  O   . GLY A 1 616 ? 209.133 191.638 152.906 1.00 66.37  ? 616 GLY A O   1 
ATOM   4746  N  N   . ARG A 1 617 ? 210.652 190.286 153.875 1.00 63.93  ? 617 ARG A N   1 
ATOM   4747  C  CA  . ARG A 1 617 ? 211.146 189.820 152.591 1.00 63.53  ? 617 ARG A CA  1 
ATOM   4748  C  C   . ARG A 1 617 ? 210.046 189.127 151.812 1.00 57.10  ? 617 ARG A C   1 
ATOM   4749  O  O   . ARG A 1 617 ? 209.910 189.333 150.601 1.00 61.89  ? 617 ARG A O   1 
ATOM   4750  C  CB  . ARG A 1 617 ? 212.334 188.887 152.790 1.00 68.83  ? 617 ARG A CB  1 
ATOM   4751  C  CG  . ARG A 1 617 ? 213.473 189.151 151.833 1.00 76.54  ? 617 ARG A CG  1 
ATOM   4752  C  CD  . ARG A 1 617 ? 214.501 188.039 151.879 1.00 78.54  ? 617 ARG A CD  1 
ATOM   4753  N  NE  . ARG A 1 617 ? 215.029 187.835 153.222 1.00 84.51  ? 617 ARG A NE  1 
ATOM   4754  C  CZ  . ARG A 1 617 ? 215.624 186.722 153.629 1.00 86.51  ? 617 ARG A CZ  1 
ATOM   4755  N  NH1 . ARG A 1 617 ? 215.779 185.687 152.820 1.00 83.76  ? 617 ARG A NH1 1 
ATOM   4756  N  NH2 . ARG A 1 617 ? 216.074 186.646 154.878 1.00 84.56  ? 617 ARG A NH2 1 
ATOM   4757  N  N   . TRP A 1 618 ? 209.241 188.313 152.489 1.00 53.88  ? 618 TRP A N   1 
ATOM   4758  C  CA  . TRP A 1 618 ? 208.200 187.587 151.780 1.00 52.25  ? 618 TRP A CA  1 
ATOM   4759  C  C   . TRP A 1 618 ? 207.172 188.537 151.194 1.00 56.02  ? 618 TRP A C   1 
ATOM   4760  O  O   . TRP A 1 618 ? 206.746 188.363 150.048 1.00 60.31  ? 618 TRP A O   1 
ATOM   4761  C  CB  . TRP A 1 618 ? 207.527 186.577 152.699 1.00 51.98  ? 618 TRP A CB  1 
ATOM   4762  C  CG  . TRP A 1 618 ? 206.468 185.800 152.010 1.00 50.44  ? 618 TRP A CG  1 
ATOM   4763  C  CD1 . TRP A 1 618 ? 206.604 184.559 151.472 1.00 58.07  ? 618 TRP A CD1 1 
ATOM   4764  C  CD2 . TRP A 1 618 ? 205.103 186.174 151.812 1.00 46.86  ? 618 TRP A CD2 1 
ATOM   4765  N  NE1 . TRP A 1 618 ? 205.420 184.146 150.926 1.00 57.19  ? 618 TRP A NE1 1 
ATOM   4766  C  CE2 . TRP A 1 618 ? 204.480 185.119 151.124 1.00 49.44  ? 618 TRP A CE2 1 
ATOM   4767  C  CE3 . TRP A 1 618 ? 204.352 187.299 152.134 1.00 51.21  ? 618 TRP A CE3 1 
ATOM   4768  C  CZ2 . TRP A 1 618 ? 203.148 185.154 150.757 1.00 48.46  ? 618 TRP A CZ2 1 
ATOM   4769  C  CZ3 . TRP A 1 618 ? 203.025 187.332 151.768 1.00 53.99  ? 618 TRP A CZ3 1 
ATOM   4770  C  CH2 . TRP A 1 618 ? 202.436 186.266 151.086 1.00 49.65  ? 618 TRP A CH2 1 
ATOM   4771  N  N   . VAL A 1 619 ? 206.765 189.555 151.955 1.00 54.26  ? 619 VAL A N   1 
ATOM   4772  C  CA  . VAL A 1 619 ? 205.735 190.455 151.445 1.00 56.30  ? 619 VAL A CA  1 
ATOM   4773  C  C   . VAL A 1 619 ? 206.258 191.258 150.263 1.00 59.79  ? 619 VAL A C   1 
ATOM   4774  O  O   . VAL A 1 619 ? 205.557 191.428 149.257 1.00 62.74  ? 619 VAL A O   1 
ATOM   4775  C  CB  . VAL A 1 619 ? 205.179 191.364 152.557 1.00 56.76  ? 619 VAL A CB  1 
ATOM   4776  C  CG1 . VAL A 1 619 ? 206.189 192.391 152.985 1.00 61.26  ? 619 VAL A CG1 1 
ATOM   4777  C  CG2 . VAL A 1 619 ? 203.935 192.056 152.068 1.00 55.67  ? 619 VAL A CG2 1 
ATOM   4778  N  N   . ILE A 1 620 ? 207.504 191.729 150.337 1.00 58.36  ? 620 ILE A N   1 
ATOM   4779  C  CA  . ILE A 1 620 ? 208.035 192.513 149.227 1.00 55.87  ? 620 ILE A CA  1 
ATOM   4780  C  C   . ILE A 1 620 ? 208.194 191.644 147.982 1.00 59.42  ? 620 ILE A C   1 
ATOM   4781  O  O   . ILE A 1 620 ? 207.811 192.045 146.871 1.00 61.91  ? 620 ILE A O   1 
ATOM   4782  C  CB  . ILE A 1 620 ? 209.357 193.174 149.636 1.00 54.58  ? 620 ILE A CB  1 
ATOM   4783  C  CG1 . ILE A 1 620 ? 209.110 194.167 150.767 1.00 57.44  ? 620 ILE A CG1 1 
ATOM   4784  C  CG2 . ILE A 1 620 ? 209.942 193.914 148.473 1.00 53.91  ? 620 ILE A CG2 1 
ATOM   4785  C  CD1 . ILE A 1 620 ? 210.307 195.031 151.092 1.00 64.03  ? 620 ILE A CD1 1 
ATOM   4786  N  N   . ALA A 1 621 ? 208.745 190.436 148.145 1.00 57.99  ? 621 ALA A N   1 
ATOM   4787  C  CA  . ALA A 1 621 ? 208.938 189.547 147.008 1.00 52.26  ? 621 ALA A CA  1 
ATOM   4788  C  C   . ALA A 1 621 ? 207.611 189.155 146.375 1.00 57.08  ? 621 ALA A C   1 
ATOM   4789  O  O   . ALA A 1 621 ? 207.489 189.120 145.145 1.00 64.33  ? 621 ALA A O   1 
ATOM   4790  C  CB  . ALA A 1 621 ? 209.708 188.306 147.445 1.00 47.45  ? 621 ALA A CB  1 
ATOM   4791  N  N   . GLU A 1 622 ? 206.599 188.862 147.192 1.00 57.26  ? 622 GLU A N   1 
ATOM   4792  C  CA  . GLU A 1 622 ? 205.294 188.499 146.651 1.00 63.07  ? 622 GLU A CA  1 
ATOM   4793  C  C   . GLU A 1 622 ? 204.646 189.661 145.915 1.00 66.13  ? 622 GLU A C   1 
ATOM   4794  O  O   . GLU A 1 622 ? 204.006 189.461 144.876 1.00 66.67  ? 622 GLU A O   1 
ATOM   4795  C  CB  . GLU A 1 622 ? 204.380 188.007 147.769 1.00 61.92  ? 622 GLU A CB  1 
ATOM   4796  C  CG  . GLU A 1 622 ? 203.565 186.786 147.404 1.00 63.41  ? 622 GLU A CG  1 
ATOM   4797  C  CD  . GLU A 1 622 ? 202.396 187.127 146.506 1.00 61.95  ? 622 GLU A CD  1 
ATOM   4798  O  OE1 . GLU A 1 622 ? 201.991 188.306 146.486 1.00 60.21  ? 622 GLU A OE1 1 
ATOM   4799  O  OE2 . GLU A 1 622 ? 201.877 186.218 145.826 1.00 63.69  ? 622 GLU A OE2 1 
ATOM   4800  N  N   . ALA A 1 623 ? 204.782 190.881 146.439 1.00 65.05  ? 623 ALA A N   1 
ATOM   4801  C  CA  . ALA A 1 623 ? 204.241 192.028 145.721 1.00 65.09  ? 623 ALA A CA  1 
ATOM   4802  C  C   . ALA A 1 623 ? 204.910 192.185 144.363 1.00 70.80  ? 623 ALA A C   1 
ATOM   4803  O  O   . ALA A 1 623 ? 204.233 192.404 143.347 1.00 70.89  ? 623 ALA A O   1 
ATOM   4804  C  CB  . ALA A 1 623 ? 204.409 193.298 146.555 1.00 59.68  ? 623 ALA A CB  1 
ATOM   4805  N  N   . CYS A 1 624 ? 206.239 192.071 144.321 1.00 71.76  ? 624 CYS A N   1 
ATOM   4806  C  CA  . CYS A 1 624 ? 206.934 192.185 143.042 1.00 72.39  ? 624 CYS A CA  1 
ATOM   4807  C  C   . CYS A 1 624 ? 206.495 191.086 142.085 1.00 75.85  ? 624 CYS A C   1 
ATOM   4808  O  O   . CYS A 1 624 ? 206.349 191.321 140.877 1.00 78.39  ? 624 CYS A O   1 
ATOM   4809  C  CB  . CYS A 1 624 ? 208.446 192.141 143.251 1.00 68.49  ? 624 CYS A CB  1 
ATOM   4810  S  SG  . CYS A 1 624 ? 209.177 193.697 143.772 1.00 78.88  ? 624 CYS A SG  1 
ATOM   4811  N  N   . ARG A 1 625 ? 206.282 189.875 142.607 1.00 73.85  ? 625 ARG A N   1 
ATOM   4812  C  CA  . ARG A 1 625 ? 205.817 188.776 141.767 1.00 70.67  ? 625 ARG A CA  1 
ATOM   4813  C  C   . ARG A 1 625 ? 204.446 189.075 141.182 1.00 66.58  ? 625 ARG A C   1 
ATOM   4814  O  O   . ARG A 1 625 ? 204.194 188.815 140.002 1.00 70.04  ? 625 ARG A O   1 
ATOM   4815  C  CB  . ARG A 1 625 ? 205.777 187.478 142.573 1.00 69.24  ? 625 ARG A CB  1 
ATOM   4816  C  CG  . ARG A 1 625 ? 205.183 186.303 141.815 1.00 69.91  ? 625 ARG A CG  1 
ATOM   4817  C  CD  . ARG A 1 625 ? 204.861 185.140 142.726 1.00 64.88  ? 625 ARG A CD  1 
ATOM   4818  N  NE  . ARG A 1 625 ? 203.502 185.216 143.235 1.00 62.78  ? 625 ARG A NE  1 
ATOM   4819  C  CZ  . ARG A 1 625 ? 202.420 184.966 142.514 1.00 68.18  ? 625 ARG A CZ  1 
ATOM   4820  N  NH1 . ARG A 1 625 ? 202.503 184.604 141.245 1.00 70.22  ? 625 ARG A NH1 1 
ATOM   4821  N  NH2 . ARG A 1 625 ? 201.223 185.073 143.083 1.00 70.74  ? 625 ARG A NH2 1 
ATOM   4822  N  N   . GLN A 1 626 ? 203.545 189.612 141.997 1.00 61.85  ? 626 GLN A N   1 
ATOM   4823  C  CA  . GLN A 1 626 ? 202.218 189.933 141.497 1.00 64.11  ? 626 GLN A CA  1 
ATOM   4824  C  C   . GLN A 1 626 ? 202.288 191.003 140.425 1.00 71.80  ? 626 GLN A C   1 
ATOM   4825  O  O   . GLN A 1 626 ? 201.553 190.945 139.435 1.00 73.91  ? 626 GLN A O   1 
ATOM   4826  C  CB  . GLN A 1 626 ? 201.322 190.387 142.642 1.00 64.06  ? 626 GLN A CB  1 
ATOM   4827  C  CG  . GLN A 1 626 ? 199.858 190.446 142.284 1.00 56.42  ? 626 GLN A CG  1 
ATOM   4828  C  CD  . GLN A 1 626 ? 199.186 189.119 142.439 1.00 50.41  ? 626 GLN A CD  1 
ATOM   4829  O  OE1 . GLN A 1 626 ? 199.845 188.092 142.511 1.00 52.43  ? 626 GLN A OE1 1 
ATOM   4830  N  NE2 . GLN A 1 626 ? 197.867 189.126 142.510 1.00 50.19  ? 626 GLN A NE2 1 
ATOM   4831  N  N   . LEU A 1 627 ? 203.154 191.999 140.609 1.00 74.78  ? 627 LEU A N   1 
ATOM   4832  C  CA  . LEU A 1 627 ? 203.290 193.034 139.587 1.00 79.19  ? 627 LEU A CA  1 
ATOM   4833  C  C   . LEU A 1 627 ? 203.829 192.456 138.281 1.00 80.27  ? 627 LEU A C   1 
ATOM   4834  O  O   . LEU A 1 627 ? 203.321 192.770 137.194 1.00 80.33  ? 627 LEU A O   1 
ATOM   4835  C  CB  . LEU A 1 627 ? 204.190 194.161 140.092 1.00 76.76  ? 627 LEU A CB  1 
ATOM   4836  C  CG  . LEU A 1 627 ? 203.658 194.925 141.306 1.00 74.48  ? 627 LEU A CG  1 
ATOM   4837  C  CD1 . LEU A 1 627 ? 204.557 196.107 141.633 1.00 75.68  ? 627 LEU A CD1 1 
ATOM   4838  C  CD2 . LEU A 1 627 ? 202.227 195.381 141.073 1.00 71.16  ? 627 LEU A CD2 1 
ATOM   4839  N  N   . ALA A 1 628 ? 204.851 191.599 138.369 1.00 79.03  ? 628 ALA A N   1 
ATOM   4840  C  CA  . ALA A 1 628 ? 205.410 190.995 137.164 1.00 76.16  ? 628 ALA A CA  1 
ATOM   4841  C  C   . ALA A 1 628 ? 204.417 190.060 136.488 1.00 78.35  ? 628 ALA A C   1 
ATOM   4842  O  O   . ALA A 1 628 ? 204.475 189.876 135.267 1.00 80.54  ? 628 ALA A O   1 
ATOM   4843  C  CB  . ALA A 1 628 ? 206.702 190.251 137.492 1.00 70.36  ? 628 ALA A CB  1 
ATOM   4844  N  N   . GLU A 1 629 ? 203.515 189.447 137.256 1.00 77.83  ? 629 GLU A N   1 
ATOM   4845  C  CA  . GLU A 1 629 ? 202.503 188.583 136.658 1.00 75.07  ? 629 GLU A CA  1 
ATOM   4846  C  C   . GLU A 1 629 ? 201.378 189.396 136.029 1.00 71.13  ? 629 GLU A C   1 
ATOM   4847  O  O   . GLU A 1 629 ? 200.841 189.010 134.988 1.00 73.51  ? 629 GLU A O   1 
ATOM   4848  C  CB  . GLU A 1 629 ? 201.985 187.597 137.715 1.00 75.91  ? 629 GLU A CB  1 
ATOM   4849  C  CG  . GLU A 1 629 ? 200.930 186.566 137.281 1.00 77.99  ? 629 GLU A CG  1 
ATOM   4850  C  CD  . GLU A 1 629 ? 199.513 187.104 137.100 1.00 80.27  ? 629 GLU A CD  1 
ATOM   4851  O  OE1 . GLU A 1 629 ? 199.263 188.305 137.314 1.00 78.38  ? 629 GLU A OE1 1 
ATOM   4852  O  OE2 . GLU A 1 629 ? 198.630 186.296 136.740 1.00 82.28  ? 629 GLU A OE2 1 
ATOM   4853  N  N   . TRP A 1 630 ? 200.998 190.506 136.652 1.00 66.43  ? 630 TRP A N   1 
ATOM   4854  C  CA  . TRP A 1 630 ? 199.918 191.330 136.135 1.00 66.71  ? 630 TRP A CA  1 
ATOM   4855  C  C   . TRP A 1 630 ? 200.338 192.177 134.948 1.00 71.85  ? 630 TRP A C   1 
ATOM   4856  O  O   . TRP A 1 630 ? 199.474 192.621 134.186 1.00 72.50  ? 630 TRP A O   1 
ATOM   4857  C  CB  . TRP A 1 630 ? 199.380 192.232 137.240 1.00 66.85  ? 630 TRP A CB  1 
ATOM   4858  C  CG  . TRP A 1 630 ? 198.222 191.661 137.985 1.00 65.56  ? 630 TRP A CG  1 
ATOM   4859  C  CD1 . TRP A 1 630 ? 197.357 190.702 137.553 1.00 63.24  ? 630 TRP A CD1 1 
ATOM   4860  C  CD2 . TRP A 1 630 ? 197.799 192.017 139.302 1.00 55.74  ? 630 TRP A CD2 1 
ATOM   4861  N  NE1 . TRP A 1 630 ? 196.420 190.445 138.515 1.00 54.61  ? 630 TRP A NE1 1 
ATOM   4862  C  CE2 . TRP A 1 630 ? 196.669 191.243 139.598 1.00 52.50  ? 630 TRP A CE2 1 
ATOM   4863  C  CE3 . TRP A 1 630 ? 198.263 192.923 140.253 1.00 51.87  ? 630 TRP A CE3 1 
ATOM   4864  C  CZ2 . TRP A 1 630 ? 196.003 191.340 140.803 1.00 50.99  ? 630 TRP A CZ2 1 
ATOM   4865  C  CZ3 . TRP A 1 630 ? 197.597 193.021 141.446 1.00 51.60  ? 630 TRP A CZ3 1 
ATOM   4866  C  CH2 . TRP A 1 630 ? 196.481 192.234 141.715 1.00 51.15  ? 630 TRP A CH2 1 
ATOM   4867  N  N   . ARG A 1 631 ? 201.636 192.427 134.783 1.00 74.19  ? 631 ARG A N   1 
ATOM   4868  C  CA  . ARG A 1 631 ? 202.093 193.103 133.576 1.00 75.70  ? 631 ARG A CA  1 
ATOM   4869  C  C   . ARG A 1 631 ? 201.907 192.247 132.335 1.00 76.96  ? 631 ARG A C   1 
ATOM   4870  O  O   . ARG A 1 631 ? 202.059 192.760 131.221 1.00 78.43  ? 631 ARG A O   1 
ATOM   4871  C  CB  . ARG A 1 631 ? 203.563 193.495 133.711 1.00 75.13  ? 631 ARG A CB  1 
ATOM   4872  C  CG  . ARG A 1 631 ? 204.525 192.371 133.381 1.00 76.95  ? 631 ARG A CG  1 
ATOM   4873  C  CD  . ARG A 1 631 ? 205.737 192.867 132.624 1.00 77.08  ? 631 ARG A CD  1 
ATOM   4874  N  NE  . ARG A 1 631 ? 206.337 194.034 133.255 1.00 80.74  ? 631 ARG A NE  1 
ATOM   4875  C  CZ  . ARG A 1 631 ? 207.301 193.978 134.162 1.00 81.80  ? 631 ARG A CZ  1 
ATOM   4876  N  NH1 . ARG A 1 631 ? 207.779 192.822 134.591 1.00 80.20  ? 631 ARG A NH1 1 
ATOM   4877  N  NH2 . ARG A 1 631 ? 207.796 195.109 134.655 1.00 83.96  ? 631 ARG A NH2 1 
ATOM   4878  N  N   . SER A 1 632 ? 201.598 190.960 132.503 1.00 75.33  ? 632 SER A N   1 
ATOM   4879  C  CA  . SER A 1 632 ? 201.401 190.077 131.361 1.00 70.94  ? 632 SER A CA  1 
ATOM   4880  C  C   . SER A 1 632 ? 200.210 190.518 130.522 1.00 75.83  ? 632 SER A C   1 
ATOM   4881  O  O   . SER A 1 632 ? 200.314 190.650 129.298 1.00 80.23  ? 632 SER A O   1 
ATOM   4882  C  CB  . SER A 1 632 ? 201.208 188.643 131.844 1.00 67.05  ? 632 SER A CB  1 
ATOM   4883  O  OG  . SER A 1 632 ? 199.847 188.397 132.130 1.00 62.22  ? 632 SER A OG  1 
ATOM   4884  N  N   . GLN A 1 633 ? 199.064 190.751 131.164 1.00 78.50  ? 633 GLN A N   1 
ATOM   4885  C  CA  . GLN A 1 633 ? 197.861 191.100 130.414 1.00 83.50  ? 633 GLN A CA  1 
ATOM   4886  C  C   . GLN A 1 633 ? 197.925 192.527 129.874 1.00 86.63  ? 633 GLN A C   1 
ATOM   4887  O  O   . GLN A 1 633 ? 197.597 192.764 128.706 1.00 83.23  ? 633 GLN A O   1 
ATOM   4888  C  CB  . GLN A 1 633 ? 196.624 190.903 131.286 1.00 79.38  ? 633 GLN A CB  1 
ATOM   4889  C  CG  . GLN A 1 633 ? 196.604 189.586 132.036 1.00 72.64  ? 633 GLN A CG  1 
ATOM   4890  C  CD  . GLN A 1 633 ? 196.903 188.403 131.143 1.00 75.91  ? 633 GLN A CD  1 
ATOM   4891  O  OE1 . GLN A 1 633 ? 197.924 187.735 131.303 1.00 76.60  ? 633 GLN A OE1 1 
ATOM   4892  N  NE2 . GLN A 1 633 ? 196.013 188.136 130.194 1.00 78.11  ? 633 GLN A NE2 1 
ATOM   4893  N  N   . ASN A 1 634 ? 198.343 193.484 130.697 1.00 88.71  ? 634 ASN A N   1 
ATOM   4894  C  CA  . ASN A 1 634 ? 198.455 194.888 130.294 1.00 94.58  ? 634 ASN A CA  1 
ATOM   4895  C  C   . ASN A 1 634 ? 199.245 195.630 131.369 1.00 92.21  ? 634 ASN A C   1 
ATOM   4896  O  O   . ASN A 1 634 ? 199.749 195.023 132.322 1.00 86.78  ? 634 ASN A O   1 
ATOM   4897  C  CB  . ASN A 1 634 ? 197.078 195.516 130.066 1.00 99.76  ? 634 ASN A CB  1 
ATOM   4898  C  CG  . ASN A 1 634 ? 197.046 196.427 128.854 1.00 100.41 ? 634 ASN A CG  1 
ATOM   4899  O  OD1 . ASN A 1 634 ? 198.053 196.604 128.168 1.00 101.37 ? 634 ASN A OD1 1 
ATOM   4900  N  ND2 . ASN A 1 634 ? 195.885 197.014 128.585 1.00 98.23  ? 634 ASN A ND2 1 
ATOM   4901  N  N   . ILE A 1 635 ? 199.351 196.955 131.216 1.00 95.38  ? 635 ILE A N   1 
ATOM   4902  C  CA  . ILE A 1 635 ? 200.050 197.774 132.205 1.00 97.05  ? 635 ILE A CA  1 
ATOM   4903  C  C   . ILE A 1 635 ? 199.333 197.716 133.548 1.00 90.00  ? 635 ILE A C   1 
ATOM   4904  O  O   . ILE A 1 635 ? 199.972 197.673 134.607 1.00 84.64  ? 635 ILE A O   1 
ATOM   4905  C  CB  . ILE A 1 635 ? 200.192 199.222 131.702 1.00 99.95  ? 635 ILE A CB  1 
ATOM   4906  C  CG1 . ILE A 1 635 ? 198.869 199.723 131.116 1.00 100.39 ? 635 ILE A CG1 1 
ATOM   4907  C  CG2 . ILE A 1 635 ? 201.311 199.323 130.676 1.00 96.17  ? 635 ILE A CG2 1 
ATOM   4908  C  CD1 . ILE A 1 635 ? 198.950 201.111 130.516 1.00 99.92  ? 635 ILE A CD1 1 
ATOM   4909  N  N   . HIS A 1 636 ? 198.002 197.739 133.525 1.00 86.16  ? 636 HIS A N   1 
ATOM   4910  C  CA  . HIS A 1 636 ? 197.191 197.470 134.703 1.00 82.41  ? 636 HIS A CA  1 
ATOM   4911  C  C   . HIS A 1 636 ? 197.434 198.473 135.822 1.00 80.00  ? 636 HIS A C   1 
ATOM   4912  O  O   . HIS A 1 636 ? 196.950 199.608 135.774 1.00 79.86  ? 636 HIS A O   1 
ATOM   4913  C  CB  . HIS A 1 636 ? 197.461 196.053 135.221 1.00 83.52  ? 636 HIS A CB  1 
ATOM   4914  C  CG  . HIS A 1 636 ? 196.669 194.988 134.528 1.00 81.99  ? 636 HIS A CG  1 
ATOM   4915  N  ND1 . HIS A 1 636 ? 196.866 194.655 133.207 1.00 79.66  ? 636 HIS A ND1 1 
ATOM   4916  C  CD2 . HIS A 1 636 ? 195.695 194.165 134.982 1.00 75.09  ? 636 HIS A CD2 1 
ATOM   4917  C  CE1 . HIS A 1 636 ? 196.036 193.685 132.872 1.00 76.61  ? 636 HIS A CE1 1 
ATOM   4918  N  NE2 . HIS A 1 636 ? 195.318 193.366 133.932 1.00 72.81  ? 636 HIS A NE2 1 
ATOM   4919  N  N   . ILE A 1 637 ? 198.199 198.054 136.820 1.00 78.65  ? 637 ILE A N   1 
ATOM   4920  C  CA  . ILE A 1 637 ? 198.204 198.717 138.126 1.00 76.38  ? 637 ILE A CA  1 
ATOM   4921  C  C   . ILE A 1 637 ? 198.976 200.030 138.025 1.00 76.19  ? 637 ILE A C   1 
ATOM   4922  O  O   . ILE A 1 637 ? 200.122 200.032 137.549 1.00 77.04  ? 637 ILE A O   1 
ATOM   4923  C  CB  . ILE A 1 637 ? 198.808 197.803 139.180 1.00 70.26  ? 637 ILE A CB  1 
ATOM   4924  C  CG1 . ILE A 1 637 ? 197.878 196.618 139.418 1.00 64.58  ? 637 ILE A CG1 1 
ATOM   4925  C  CG2 . ILE A 1 637 ? 199.038 198.563 140.471 1.00 70.72  ? 637 ILE A CG2 1 
ATOM   4926  C  CD1 . ILE A 1 637 ? 196.415 196.992 139.412 1.00 57.41  ? 637 ILE A CD1 1 
ATOM   4927  N  N   . PRO A 1 638 ? 198.388 201.150 138.454 1.00 67.53  ? 638 PRO A N   1 
ATOM   4928  C  CA  . PRO A 1 638 ? 199.148 202.409 138.464 1.00 63.24  ? 638 PRO A CA  1 
ATOM   4929  C  C   . PRO A 1 638 ? 200.290 202.411 139.463 1.00 68.39  ? 638 PRO A C   1 
ATOM   4930  O  O   . PRO A 1 638 ? 201.432 202.705 139.090 1.00 73.99  ? 638 PRO A O   1 
ATOM   4931  C  CB  . PRO A 1 638 ? 198.076 203.453 138.800 1.00 60.23  ? 638 PRO A CB  1 
ATOM   4932  C  CG  . PRO A 1 638 ? 196.775 202.788 138.518 1.00 58.37  ? 638 PRO A CG  1 
ATOM   4933  C  CD  . PRO A 1 638 ? 196.977 201.352 138.807 1.00 62.28  ? 638 PRO A CD  1 
ATOM   4934  N  N   . ALA A 1 639 ? 200.023 202.082 140.725 1.00 66.30  ? 639 ALA A N   1 
ATOM   4935  C  CA  . ALA A 1 639 ? 201.078 202.066 141.728 1.00 64.52  ? 639 ALA A CA  1 
ATOM   4936  C  C   . ALA A 1 639 ? 200.704 201.112 142.854 1.00 60.02  ? 639 ALA A C   1 
ATOM   4937  O  O   . ALA A 1 639 ? 199.530 200.808 143.069 1.00 57.61  ? 639 ALA A O   1 
ATOM   4938  C  CB  . ALA A 1 639 ? 201.349 203.467 142.279 1.00 64.72  ? 639 ALA A CB  1 
ATOM   4939  N  N   . LEU A 1 640 ? 201.727 200.670 143.589 1.00 61.23  ? 640 LEU A N   1 
ATOM   4940  C  CA  . LEU A 1 640 ? 201.582 199.699 144.666 1.00 57.18  ? 640 LEU A CA  1 
ATOM   4941  C  C   . LEU A 1 640 ? 202.283 200.205 145.921 1.00 60.43  ? 640 LEU A C   1 
ATOM   4942  O  O   . LEU A 1 640 ? 203.286 200.917 145.840 1.00 64.35  ? 640 LEU A O   1 
ATOM   4943  C  CB  . LEU A 1 640 ? 202.159 198.343 144.255 1.00 57.66  ? 640 LEU A CB  1 
ATOM   4944  C  CG  . LEU A 1 640 ? 202.183 197.208 145.268 1.00 54.96  ? 640 LEU A CG  1 
ATOM   4945  C  CD1 . LEU A 1 640 ? 201.548 195.969 144.676 1.00 58.89  ? 640 LEU A CD1 1 
ATOM   4946  C  CD2 . LEU A 1 640 ? 203.598 196.929 145.698 1.00 54.23  ? 640 LEU A CD2 1 
ATOM   4947  N  N   . SER A 1 641 ? 201.748 199.837 147.089 1.00 57.87  ? 641 SER A N   1 
ATOM   4948  C  CA  . SER A 1 641 ? 202.248 200.333 148.366 1.00 55.88  ? 641 SER A CA  1 
ATOM   4949  C  C   . SER A 1 641 ? 202.449 199.192 149.352 1.00 48.42  ? 641 SER A C   1 
ATOM   4950  O  O   . SER A 1 641 ? 201.714 198.203 149.345 1.00 46.18  ? 641 SER A O   1 
ATOM   4951  C  CB  . SER A 1 641 ? 201.295 201.363 148.982 1.00 52.51  ? 641 SER A CB  1 
ATOM   4952  O  OG  . SER A 1 641 ? 201.114 202.471 148.121 1.00 52.54  ? 641 SER A OG  1 
ATOM   4953  N  N   . VAL A 1 642 ? 203.459 199.345 150.205 1.00 46.55  ? 642 VAL A N   1 
ATOM   4954  C  CA  . VAL A 1 642 ? 203.747 198.421 151.294 1.00 42.93  ? 642 VAL A CA  1 
ATOM   4955  C  C   . VAL A 1 642 ? 204.005 199.236 152.553 1.00 48.60  ? 642 VAL A C   1 
ATOM   4956  O  O   . VAL A 1 642 ? 204.862 200.125 152.554 1.00 52.70  ? 642 VAL A O   1 
ATOM   4957  C  CB  . VAL A 1 642 ? 204.955 197.525 150.977 1.00 40.78  ? 642 VAL A CB  1 
ATOM   4958  C  CG1 . VAL A 1 642 ? 205.362 196.752 152.202 1.00 47.14  ? 642 VAL A CG1 1 
ATOM   4959  C  CG2 . VAL A 1 642 ? 204.624 196.585 149.847 1.00 42.54  ? 642 VAL A CG2 1 
ATOM   4960  N  N   . ASN A 1 643 ? 203.276 198.932 153.622 1.00 43.99  ? 643 ASN A N   1 
ATOM   4961  C  CA  . ASN A 1 643 ? 203.390 199.683 154.869 1.00 41.68  ? 643 ASN A CA  1 
ATOM   4962  C  C   . ASN A 1 643 ? 204.574 199.136 155.648 1.00 43.73  ? 643 ASN A C   1 
ATOM   4963  O  O   . ASN A 1 643 ? 204.508 198.049 156.222 1.00 48.65  ? 643 ASN A O   1 
ATOM   4964  C  CB  . ASN A 1 643 ? 202.101 199.578 155.673 1.00 41.74  ? 643 ASN A CB  1 
ATOM   4965  C  CG  . ASN A 1 643 ? 202.054 200.544 156.836 1.00 50.66  ? 643 ASN A CG  1 
ATOM   4966  O  OD1 . ASN A 1 643 ? 203.053 200.770 157.515 1.00 55.30  ? 643 ASN A OD1 1 
ATOM   4967  N  ND2 . ASN A 1 643 ? 200.882 201.113 157.081 1.00 50.15  ? 643 ASN A ND2 1 
ATOM   4968  N  N   . LEU A 1 644 ? 205.671 199.888 155.664 1.00 43.27  ? 644 LEU A N   1 
ATOM   4969  C  CA  . LEU A 1 644 ? 206.865 199.449 156.372 1.00 44.92  ? 644 LEU A CA  1 
ATOM   4970  C  C   . LEU A 1 644 ? 206.745 199.644 157.873 1.00 49.44  ? 644 LEU A C   1 
ATOM   4971  O  O   . LEU A 1 644 ? 207.320 198.867 158.640 1.00 56.39  ? 644 LEU A O   1 
ATOM   4972  C  CB  . LEU A 1 644 ? 208.091 200.193 155.856 1.00 47.22  ? 644 LEU A CB  1 
ATOM   4973  C  CG  . LEU A 1 644 ? 208.897 199.576 154.721 1.00 53.50  ? 644 LEU A CG  1 
ATOM   4974  C  CD1 . LEU A 1 644 ? 207.989 198.966 153.677 1.00 52.87  ? 644 LEU A CD1 1 
ATOM   4975  C  CD2 . LEU A 1 644 ? 209.803 200.614 154.107 1.00 54.25  ? 644 LEU A CD2 1 
ATOM   4976  N  N   . SER A 1 645 ? 206.030 200.677 158.313 1.00 48.68  ? 645 SER A N   1 
ATOM   4977  C  CA  . SER A 1 645 ? 205.882 200.911 159.744 1.00 52.74  ? 645 SER A CA  1 
ATOM   4978  C  C   . SER A 1 645 ? 205.116 199.781 160.412 1.00 56.98  ? 645 SER A C   1 
ATOM   4979  O  O   . SER A 1 645 ? 205.485 199.335 161.504 1.00 60.30  ? 645 SER A O   1 
ATOM   4980  C  CB  . SER A 1 645 ? 205.182 202.245 159.988 1.00 54.83  ? 645 SER A CB  1 
ATOM   4981  O  OG  . SER A 1 645 ? 204.728 202.340 161.327 1.00 56.42  ? 645 SER A OG  1 
ATOM   4982  N  N   . ALA A 1 646 ? 204.040 199.310 159.781 1.00 54.79  ? 646 ALA A N   1 
ATOM   4983  C  CA  . ALA A 1 646 ? 203.268 198.214 160.352 1.00 54.21  ? 646 ALA A CA  1 
ATOM   4984  C  C   . ALA A 1 646 ? 204.039 196.908 160.344 1.00 53.20  ? 646 ALA A C   1 
ATOM   4985  O  O   . ALA A 1 646 ? 203.672 195.980 161.071 1.00 53.56  ? 646 ALA A O   1 
ATOM   4986  C  CB  . ALA A 1 646 ? 201.950 198.043 159.596 1.00 49.75  ? 646 ALA A CB  1 
ATOM   4987  N  N   . LEU A 1 647 ? 205.093 196.815 159.546 1.00 51.83  ? 647 LEU A N   1 
ATOM   4988  C  CA  . LEU A 1 647 ? 205.897 195.612 159.447 1.00 54.19  ? 647 LEU A CA  1 
ATOM   4989  C  C   . LEU A 1 647 ? 207.130 195.656 160.332 1.00 56.18  ? 647 LEU A C   1 
ATOM   4990  O  O   . LEU A 1 647 ? 207.955 194.744 160.264 1.00 58.28  ? 647 LEU A O   1 
ATOM   4991  C  CB  . LEU A 1 647 ? 206.303 195.373 157.989 1.00 52.90  ? 647 LEU A CB  1 
ATOM   4992  C  CG  . LEU A 1 647 ? 205.432 194.409 157.183 1.00 49.59  ? 647 LEU A CG  1 
ATOM   4993  C  CD1 . LEU A 1 647 ? 203.962 194.685 157.374 1.00 48.95  ? 647 LEU A CD1 1 
ATOM   4994  C  CD2 . LEU A 1 647 ? 205.774 194.521 155.731 1.00 45.45  ? 647 LEU A CD2 1 
ATOM   4995  N  N   . HIS A 1 648 ? 207.278 196.698 161.147 1.00 53.04  ? 648 HIS A N   1 
ATOM   4996  C  CA  . HIS A 1 648 ? 208.379 196.805 162.098 1.00 52.59  ? 648 HIS A CA  1 
ATOM   4997  C  C   . HIS A 1 648 ? 209.728 196.653 161.405 1.00 56.20  ? 648 HIS A C   1 
ATOM   4998  O  O   . HIS A 1 648 ? 210.653 196.040 161.938 1.00 65.06  ? 648 HIS A O   1 
ATOM   4999  C  CB  . HIS A 1 648 ? 208.227 195.785 163.224 1.00 56.44  ? 648 HIS A CB  1 
ATOM   5000  C  CG  . HIS A 1 648 ? 207.043 196.031 164.101 1.00 60.71  ? 648 HIS A CG  1 
ATOM   5001  N  ND1 . HIS A 1 648 ? 206.690 195.185 165.128 1.00 63.84  ? 648 HIS A ND1 1 
ATOM   5002  C  CD2 . HIS A 1 648 ? 206.132 197.031 164.108 1.00 62.53  ? 648 HIS A CD2 1 
ATOM   5003  C  CE1 . HIS A 1 648 ? 205.608 195.649 165.726 1.00 64.28  ? 648 HIS A CE1 1 
ATOM   5004  N  NE2 . HIS A 1 648 ? 205.250 196.769 165.128 1.00 66.71  ? 648 HIS A NE2 1 
ATOM   5005  N  N   . PHE A 1 649 ? 209.841 197.213 160.207 1.00 53.02  ? 649 PHE A N   1 
ATOM   5006  C  CA  . PHE A 1 649 ? 211.082 197.117 159.458 1.00 56.22  ? 649 PHE A CA  1 
ATOM   5007  C  C   . PHE A 1 649 ? 212.215 197.785 160.218 1.00 62.23  ? 649 PHE A C   1 
ATOM   5008  O  O   . PHE A 1 649 ? 212.041 198.847 160.820 1.00 62.89  ? 649 PHE A O   1 
ATOM   5009  C  CB  . PHE A 1 649 ? 210.919 197.757 158.090 1.00 56.21  ? 649 PHE A CB  1 
ATOM   5010  C  CG  . PHE A 1 649 ? 210.632 196.779 156.997 1.00 63.51  ? 649 PHE A CG  1 
ATOM   5011  C  CD1 . PHE A 1 649 ? 209.368 196.678 156.454 1.00 64.11  ? 649 PHE A CD1 1 
ATOM   5012  C  CD2 . PHE A 1 649 ? 211.635 195.975 156.496 1.00 72.19  ? 649 PHE A CD2 1 
ATOM   5013  C  CE1 . PHE A 1 649 ? 209.107 195.784 155.438 1.00 66.21  ? 649 PHE A CE1 1 
ATOM   5014  C  CE2 . PHE A 1 649 ? 211.379 195.080 155.481 1.00 74.88  ? 649 PHE A CE2 1 
ATOM   5015  C  CZ  . PHE A 1 649 ? 210.112 194.985 154.952 1.00 68.33  ? 649 PHE A CZ  1 
ATOM   5016  N  N   . ARG A 1 650 ? 213.377 197.149 160.198 1.00 68.65  ? 650 ARG A N   1 
ATOM   5017  C  CA  . ARG A 1 650 ? 214.538 197.615 160.930 1.00 75.32  ? 650 ARG A CA  1 
ATOM   5018  C  C   . ARG A 1 650 ? 215.430 198.462 160.030 1.00 84.63  ? 650 ARG A C   1 
ATOM   5019  O  O   . ARG A 1 650 ? 215.074 198.805 158.901 1.00 85.01  ? 650 ARG A O   1 
ATOM   5020  C  CB  . ARG A 1 650 ? 215.308 196.433 161.512 1.00 77.01  ? 650 ARG A CB  1 
ATOM   5021  C  CG  . ARG A 1 650 ? 214.676 195.818 162.736 1.00 78.47  ? 650 ARG A CG  1 
ATOM   5022  C  CD  . ARG A 1 650 ? 214.588 194.316 162.602 1.00 80.45  ? 650 ARG A CD  1 
ATOM   5023  N  NE  . ARG A 1 650 ? 214.427 193.672 163.898 1.00 85.91  ? 650 ARG A NE  1 
ATOM   5024  C  CZ  . ARG A 1 650 ? 213.329 193.732 164.637 1.00 85.09  ? 650 ARG A CZ  1 
ATOM   5025  N  NH1 . ARG A 1 650 ? 212.254 194.387 164.228 1.00 81.52  ? 650 ARG A NH1 1 
ATOM   5026  N  NH2 . ARG A 1 650 ? 213.307 193.119 165.816 1.00 87.27  ? 650 ARG A NH2 1 
ATOM   5027  N  N   . SER A 1 651 ? 216.614 198.802 160.539 1.00 91.14  ? 651 SER A N   1 
ATOM   5028  C  CA  . SER A 1 651 ? 217.515 199.697 159.830 1.00 99.23  ? 651 SER A CA  1 
ATOM   5029  C  C   . SER A 1 651 ? 218.352 198.989 158.778 1.00 101.75 ? 651 SER A C   1 
ATOM   5030  O  O   . SER A 1 651 ? 218.937 199.659 157.921 1.00 107.05 ? 651 SER A O   1 
ATOM   5031  C  CB  . SER A 1 651 ? 218.441 200.399 160.825 1.00 106.16 ? 651 SER A CB  1 
ATOM   5032  O  OG  . SER A 1 651 ? 219.203 199.456 161.558 1.00 104.78 ? 651 SER A OG  1 
ATOM   5033  N  N   . ASN A 1 652 ? 218.425 197.660 158.815 1.00 96.85  ? 652 ASN A N   1 
ATOM   5034  C  CA  . ASN A 1 652 ? 219.245 196.905 157.878 1.00 99.93  ? 652 ASN A CA  1 
ATOM   5035  C  C   . ASN A 1 652 ? 218.407 196.071 156.920 1.00 96.58  ? 652 ASN A C   1 
ATOM   5036  O  O   . ASN A 1 652 ? 218.817 194.971 156.540 1.00 96.72  ? 652 ASN A O   1 
ATOM   5037  C  CB  . ASN A 1 652 ? 220.223 196.012 158.639 1.00 103.04 ? 652 ASN A CB  1 
ATOM   5038  C  CG  . ASN A 1 652 ? 219.612 195.419 159.889 1.00 105.24 ? 652 ASN A CG  1 
ATOM   5039  O  OD1 . ASN A 1 652 ? 219.031 196.132 160.706 1.00 101.61 ? 652 ASN A OD1 1 
ATOM   5040  N  ND2 . ASN A 1 652 ? 219.742 194.108 160.047 1.00 107.53 ? 652 ASN A ND2 1 
ATOM   5041  N  N   . GLN A 1 653 ? 217.246 196.568 156.521 1.00 94.09  ? 653 GLN A N   1 
ATOM   5042  C  CA  . GLN A 1 653 ? 216.331 195.785 155.705 1.00 92.71  ? 653 GLN A CA  1 
ATOM   5043  C  C   . GLN A 1 653 ? 215.872 196.492 154.443 1.00 99.21  ? 653 GLN A C   1 
ATOM   5044  O  O   . GLN A 1 653 ? 215.627 195.832 153.435 1.00 100.55 ? 653 GLN A O   1 
ATOM   5045  C  CB  . GLN A 1 653 ? 215.103 195.394 156.527 1.00 85.95  ? 653 GLN A CB  1 
ATOM   5046  C  CG  . GLN A 1 653 ? 215.301 194.166 157.374 1.00 86.29  ? 653 GLN A CG  1 
ATOM   5047  C  CD  . GLN A 1 653 ? 213.996 193.629 157.906 1.00 83.88  ? 653 GLN A CD  1 
ATOM   5048  O  OE1 . GLN A 1 653 ? 213.164 193.135 157.149 1.00 80.62  ? 653 GLN A OE1 1 
ATOM   5049  N  NE2 . GLN A 1 653 ? 213.802 193.731 159.216 1.00 83.68  ? 653 GLN A NE2 1 
ATOM   5050  N  N   . LEU A 1 654 ? 215.742 197.818 154.469 1.00 103.28 ? 654 LEU A N   1 
ATOM   5051  C  CA  . LEU A 1 654 ? 215.095 198.518 153.360 1.00 109.09 ? 654 LEU A CA  1 
ATOM   5052  C  C   . LEU A 1 654 ? 215.880 198.426 152.055 1.00 108.69 ? 654 LEU A C   1 
ATOM   5053  O  O   . LEU A 1 654 ? 215.372 197.824 151.088 1.00 104.94 ? 654 LEU A O   1 
ATOM   5054  C  CB  . LEU A 1 654 ? 214.829 199.970 153.770 1.00 107.40 ? 654 LEU A CB  1 
ATOM   5055  C  CG  . LEU A 1 654 ? 213.515 200.277 154.488 1.00 98.68  ? 654 LEU A CG  1 
ATOM   5056  C  CD1 . LEU A 1 654 ? 213.523 199.732 155.909 1.00 89.17  ? 654 LEU A CD1 1 
ATOM   5057  C  CD2 . LEU A 1 654 ? 213.261 201.774 154.492 1.00 88.40  ? 654 LEU A CD2 1 
ATOM   5058  N  N   . PRO A 1 655 ? 217.117 198.972 151.950 1.00 110.60 ? 655 PRO A N   1 
ATOM   5059  C  CA  . PRO A 1 655 ? 217.724 199.137 150.622 1.00 107.06 ? 655 PRO A CA  1 
ATOM   5060  C  C   . PRO A 1 655 ? 218.006 197.815 149.931 1.00 103.53 ? 655 PRO A C   1 
ATOM   5061  O  O   . PRO A 1 655 ? 217.621 197.627 148.773 1.00 100.85 ? 655 PRO A O   1 
ATOM   5062  C  CB  . PRO A 1 655 ? 219.018 199.906 150.915 1.00 103.76 ? 655 PRO A CB  1 
ATOM   5063  C  CG  . PRO A 1 655 ? 219.365 199.557 152.300 1.00 104.39 ? 655 PRO A CG  1 
ATOM   5064  C  CD  . PRO A 1 655 ? 218.077 199.280 153.029 1.00 107.18 ? 655 PRO A CD  1 
ATOM   5065  N  N   . ASN A 1 656 ? 218.666 196.893 150.630 1.00 102.57 ? 656 ASN A N   1 
ATOM   5066  C  CA  . ASN A 1 656 ? 219.045 195.634 150.002 1.00 101.29 ? 656 ASN A CA  1 
ATOM   5067  C  C   . ASN A 1 656 ? 217.818 194.838 149.580 1.00 100.15 ? 656 ASN A C   1 
ATOM   5068  O  O   . ASN A 1 656 ? 217.756 194.326 148.457 1.00 100.52 ? 656 ASN A O   1 
ATOM   5069  C  CB  . ASN A 1 656 ? 219.935 194.821 150.945 1.00 102.86 ? 656 ASN A CB  1 
ATOM   5070  C  CG  . ASN A 1 656 ? 219.239 194.454 152.239 1.00 103.53 ? 656 ASN A CG  1 
ATOM   5071  O  OD1 . ASN A 1 656 ? 218.124 194.898 152.506 1.00 105.09 ? 656 ASN A OD1 1 
ATOM   5072  N  ND2 . ASN A 1 656 ? 219.896 193.634 153.050 1.00 98.50  ? 656 ASN A ND2 1 
ATOM   5073  N  N   . GLN A 1 657 ? 216.824 194.732 150.462 1.00 100.32 ? 657 GLN A N   1 
ATOM   5074  C  CA  . GLN A 1 657 ? 215.659 193.914 150.142 1.00 100.67 ? 657 GLN A CA  1 
ATOM   5075  C  C   . GLN A 1 657 ? 214.884 194.499 148.974 1.00 97.42  ? 657 GLN A C   1 
ATOM   5076  O  O   . GLN A 1 657 ? 214.499 193.775 148.049 1.00 96.51  ? 657 GLN A O   1 
ATOM   5077  C  CB  . GLN A 1 657 ? 214.760 193.758 151.366 1.00 98.09  ? 657 GLN A CB  1 
ATOM   5078  C  CG  . GLN A 1 657 ? 215.303 192.781 152.386 1.00 94.02  ? 657 GLN A CG  1 
ATOM   5079  C  CD  . GLN A 1 657 ? 214.432 192.676 153.607 1.00 87.49  ? 657 GLN A CD  1 
ATOM   5080  O  OE1 . GLN A 1 657 ? 213.774 193.638 153.994 1.00 87.22  ? 657 GLN A OE1 1 
ATOM   5081  N  NE2 . GLN A 1 657 ? 214.420 191.505 154.226 1.00 81.03  ? 657 GLN A NE2 1 
ATOM   5082  N  N   . VAL A 1 658 ? 214.665 195.814 148.980 1.00 94.60  ? 658 VAL A N   1 
ATOM   5083  C  CA  . VAL A 1 658 ? 213.933 196.415 147.870 1.00 95.40  ? 658 VAL A CA  1 
ATOM   5084  C  C   . VAL A 1 658 ? 214.720 196.277 146.570 1.00 101.88 ? 658 VAL A C   1 
ATOM   5085  O  O   . VAL A 1 658 ? 214.151 195.959 145.515 1.00 101.61 ? 658 VAL A O   1 
ATOM   5086  C  CB  . VAL A 1 658 ? 213.592 197.881 148.184 1.00 96.75  ? 658 VAL A CB  1 
ATOM   5087  C  CG1 . VAL A 1 658 ? 212.983 198.554 146.970 1.00 90.79  ? 658 VAL A CG1 1 
ATOM   5088  C  CG2 . VAL A 1 658 ? 212.638 197.953 149.363 1.00 95.61  ? 658 VAL A CG2 1 
ATOM   5089  N  N   . SER A 1 659 ? 216.036 196.505 146.618 1.00 105.38 ? 659 SER A N   1 
ATOM   5090  C  CA  . SER A 1 659 ? 216.845 196.427 145.406 1.00 104.45 ? 659 SER A CA  1 
ATOM   5091  C  C   . SER A 1 659 ? 216.808 195.026 144.811 1.00 100.96 ? 659 SER A C   1 
ATOM   5092  O  O   . SER A 1 659 ? 216.595 194.858 143.605 1.00 98.78  ? 659 SER A O   1 
ATOM   5093  C  CB  . SER A 1 659 ? 218.283 196.847 145.709 1.00 104.81 ? 659 SER A CB  1 
ATOM   5094  O  OG  . SER A 1 659 ? 218.316 198.027 146.493 1.00 102.69 ? 659 SER A OG  1 
ATOM   5095  N  N   . ASP A 1 660 ? 216.999 194.003 145.647 1.00 100.52 ? 660 ASP A N   1 
ATOM   5096  C  CA  . ASP A 1 660 ? 216.918 192.637 145.146 1.00 97.34  ? 660 ASP A CA  1 
ATOM   5097  C  C   . ASP A 1 660 ? 215.526 192.312 144.633 1.00 93.69  ? 660 ASP A C   1 
ATOM   5098  O  O   . ASP A 1 660 ? 215.387 191.613 143.622 1.00 92.74  ? 660 ASP A O   1 
ATOM   5099  C  CB  . ASP A 1 660 ? 217.332 191.644 146.231 1.00 96.63  ? 660 ASP A CB  1 
ATOM   5100  C  CG  . ASP A 1 660 ? 218.605 192.051 146.934 1.00 98.78  ? 660 ASP A CG  1 
ATOM   5101  O  OD1 . ASP A 1 660 ? 219.224 193.047 146.506 1.00 97.94  ? 660 ASP A OD1 1 
ATOM   5102  O  OD2 . ASP A 1 660 ? 218.986 191.382 147.917 1.00 99.52  ? 660 ASP A OD2 1 
ATOM   5103  N  N   . ALA A 1 661 ? 214.487 192.813 145.302 1.00 93.40  ? 661 ALA A N   1 
ATOM   5104  C  CA  . ALA A 1 661 ? 213.129 192.512 144.870 1.00 94.88  ? 661 ALA A CA  1 
ATOM   5105  C  C   . ALA A 1 661 ? 212.854 193.064 143.480 1.00 97.31  ? 661 ALA A C   1 
ATOM   5106  O  O   . ALA A 1 661 ? 212.268 192.374 142.639 1.00 95.84  ? 661 ALA A O   1 
ATOM   5107  C  CB  . ALA A 1 661 ? 212.125 193.069 145.875 1.00 89.51  ? 661 ALA A CB  1 
ATOM   5108  N  N   . MET A 1 662 ? 213.268 194.302 143.213 1.00 100.08 ? 662 MET A N   1 
ATOM   5109  C  CA  . MET A 1 662 ? 213.007 194.862 141.891 1.00 102.85 ? 662 MET A CA  1 
ATOM   5110  C  C   . MET A 1 662 ? 214.076 194.517 140.864 1.00 101.93 ? 662 MET A C   1 
ATOM   5111  O  O   . MET A 1 662 ? 213.896 194.832 139.683 1.00 95.40  ? 662 MET A O   1 
ATOM   5112  C  CB  . MET A 1 662 ? 212.836 196.385 141.946 1.00 104.31 ? 662 MET A CB  1 
ATOM   5113  C  CG  . MET A 1 662 ? 212.395 196.944 143.277 1.00 106.54 ? 662 MET A CG  1 
ATOM   5114  S  SD  . MET A 1 662 ? 212.385 198.744 143.247 1.00 114.85 ? 662 MET A SD  1 
ATOM   5115  C  CE  . MET A 1 662 ? 214.115 199.081 143.550 1.00 103.99 ? 662 MET A CE  1 
ATOM   5116  N  N   . HIS A 1 663 ? 215.174 193.880 141.270 1.00 104.24 ? 663 HIS A N   1 
ATOM   5117  C  CA  . HIS A 1 663 ? 216.126 193.383 140.285 1.00 101.75 ? 663 HIS A CA  1 
ATOM   5118  C  C   . HIS A 1 663 ? 215.791 191.970 139.826 1.00 93.66  ? 663 HIS A C   1 
ATOM   5119  O  O   . HIS A 1 663 ? 215.916 191.664 138.636 1.00 89.48  ? 663 HIS A O   1 
ATOM   5120  C  CB  . HIS A 1 663 ? 217.548 193.421 140.850 1.00 104.40 ? 663 HIS A CB  1 
ATOM   5121  C  CG  . HIS A 1 663 ? 218.216 194.753 140.715 1.00 112.06 ? 663 HIS A CG  1 
ATOM   5122  N  ND1 . HIS A 1 663 ? 218.219 195.469 139.537 1.00 112.45 ? 663 HIS A ND1 1 
ATOM   5123  C  CD2 . HIS A 1 663 ? 218.906 195.500 141.610 1.00 115.33 ? 663 HIS A CD2 1 
ATOM   5124  C  CE1 . HIS A 1 663 ? 218.880 196.599 139.713 1.00 118.11 ? 663 HIS A CE1 1 
ATOM   5125  N  NE2 . HIS A 1 663 ? 219.307 196.642 140.962 1.00 121.63 ? 663 HIS A NE2 1 
ATOM   5126  N  N   . ALA A 1 664 ? 215.357 191.106 140.747 1.00 94.37  ? 664 ALA A N   1 
ATOM   5127  C  CA  . ALA A 1 664 ? 215.028 189.733 140.381 1.00 92.50  ? 664 ALA A CA  1 
ATOM   5128  C  C   . ALA A 1 664 ? 213.872 189.691 139.391 1.00 88.77  ? 664 ALA A C   1 
ATOM   5129  O  O   . ALA A 1 664 ? 213.909 188.948 138.404 1.00 85.35  ? 664 ALA A O   1 
ATOM   5130  C  CB  . ALA A 1 664 ? 214.697 188.922 141.633 1.00 91.28  ? 664 ALA A CB  1 
ATOM   5131  N  N   . TRP A 1 665 ? 212.836 190.478 139.638 1.00 90.05  ? 665 TRP A N   1 
ATOM   5132  C  CA  . TRP A 1 665 ? 211.750 190.625 138.686 1.00 85.68  ? 665 TRP A CA  1 
ATOM   5133  C  C   . TRP A 1 665 ? 212.035 191.844 137.814 1.00 84.45  ? 665 TRP A C   1 
ATOM   5134  O  O   . TRP A 1 665 ? 213.141 192.389 137.812 1.00 84.26  ? 665 TRP A O   1 
ATOM   5135  C  CB  . TRP A 1 665 ? 210.407 190.744 139.406 1.00 85.46  ? 665 TRP A CB  1 
ATOM   5136  C  CG  . TRP A 1 665 ? 210.169 189.702 140.461 1.00 82.33  ? 665 TRP A CG  1 
ATOM   5137  C  CD1 . TRP A 1 665 ? 210.566 189.752 141.763 1.00 80.75  ? 665 TRP A CD1 1 
ATOM   5138  C  CD2 . TRP A 1 665 ? 209.480 188.458 140.299 1.00 75.07  ? 665 TRP A CD2 1 
ATOM   5139  N  NE1 . TRP A 1 665 ? 210.167 188.616 142.423 1.00 72.82  ? 665 TRP A NE1 1 
ATOM   5140  C  CE2 . TRP A 1 665 ? 209.498 187.806 141.546 1.00 67.82  ? 665 TRP A CE2 1 
ATOM   5141  C  CE3 . TRP A 1 665 ? 208.853 187.830 139.221 1.00 76.33  ? 665 TRP A CE3 1 
ATOM   5142  C  CZ2 . TRP A 1 665 ? 208.921 186.560 141.743 1.00 63.49  ? 665 TRP A CZ2 1 
ATOM   5143  C  CZ3 . TRP A 1 665 ? 208.275 186.593 139.421 1.00 73.82  ? 665 TRP A CZ3 1 
ATOM   5144  C  CH2 . TRP A 1 665 ? 208.315 185.971 140.672 1.00 68.78  ? 665 TRP A CH2 1 
ATOM   5145  N  N   . GLY A 1 666 ? 211.042 192.274 137.046 1.00 83.98  ? 666 GLY A N   1 
ATOM   5146  C  CA  . GLY A 1 666 ? 211.152 193.522 136.319 1.00 92.79  ? 666 GLY A CA  1 
ATOM   5147  C  C   . GLY A 1 666 ? 210.169 194.565 136.808 1.00 96.61  ? 666 GLY A C   1 
ATOM   5148  O  O   . GLY A 1 666 ? 208.965 194.444 136.570 1.00 95.22  ? 666 GLY A O   1 
ATOM   5149  N  N   . ILE A 1 667 ? 210.661 195.589 137.503 1.00 96.23  ? 667 ILE A N   1 
ATOM   5150  C  CA  . ILE A 1 667 ? 209.827 196.679 137.999 1.00 94.47  ? 667 ILE A CA  1 
ATOM   5151  C  C   . ILE A 1 667 ? 210.554 197.990 137.747 1.00 93.28  ? 667 ILE A C   1 
ATOM   5152  O  O   . ILE A 1 667 ? 211.730 198.129 138.095 1.00 92.09  ? 667 ILE A O   1 
ATOM   5153  C  CB  . ILE A 1 667 ? 209.498 196.526 139.496 1.00 97.01  ? 667 ILE A CB  1 
ATOM   5154  C  CG1 . ILE A 1 667 ? 208.558 195.344 139.720 1.00 95.08  ? 667 ILE A CG1 1 
ATOM   5155  C  CG2 . ILE A 1 667 ? 208.874 197.798 140.034 1.00 96.38  ? 667 ILE A CG2 1 
ATOM   5156  C  CD1 . ILE A 1 667 ? 209.258 194.094 140.191 1.00 90.95  ? 667 ILE A CD1 1 
ATOM   5157  N  N   . ASP A 1 668 ? 209.851 198.956 137.157 1.00 95.04  ? 668 ASP A N   1 
ATOM   5158  C  CA  . ASP A 1 668 ? 210.463 200.231 136.811 1.00 98.68  ? 668 ASP A CA  1 
ATOM   5159  C  C   . ASP A 1 668 ? 210.776 201.091 138.026 1.00 99.47  ? 668 ASP A C   1 
ATOM   5160  O  O   . ASP A 1 668 ? 211.455 202.113 137.879 1.00 101.82 ? 668 ASP A O   1 
ATOM   5161  C  CB  . ASP A 1 668 ? 209.552 201.007 135.858 1.00 98.12  ? 668 ASP A CB  1 
ATOM   5162  C  CG  . ASP A 1 668 ? 210.325 201.921 134.927 1.00 99.84  ? 668 ASP A CG  1 
ATOM   5163  O  OD1 . ASP A 1 668 ? 211.505 201.626 134.645 1.00 99.99  ? 668 ASP A OD1 1 
ATOM   5164  O  OD2 . ASP A 1 668 ? 209.752 202.937 134.479 1.00 98.78  ? 668 ASP A OD2 1 
ATOM   5165  N  N   . GLY A 1 669 ? 210.306 200.713 139.208 1.00 97.54  ? 669 GLY A N   1 
ATOM   5166  C  CA  . GLY A 1 669 ? 210.468 201.511 140.411 1.00 92.10  ? 669 GLY A CA  1 
ATOM   5167  C  C   . GLY A 1 669 ? 209.320 202.466 140.624 1.00 87.37  ? 669 GLY A C   1 
ATOM   5168  O  O   . GLY A 1 669 ? 208.915 202.715 141.760 1.00 85.12  ? 669 GLY A O   1 
ATOM   5169  N  N   . HIS A 1 670 ? 208.778 203.006 139.534 1.00 88.86  ? 670 HIS A N   1 
ATOM   5170  C  CA  . HIS A 1 670 ? 207.629 203.896 139.625 1.00 85.93  ? 670 HIS A CA  1 
ATOM   5171  C  C   . HIS A 1 670 ? 206.388 203.168 140.115 1.00 81.33  ? 670 HIS A C   1 
ATOM   5172  O  O   . HIS A 1 670 ? 205.438 203.815 140.566 1.00 79.29  ? 670 HIS A O   1 
ATOM   5173  C  CB  . HIS A 1 670 ? 207.375 204.540 138.257 1.00 88.66  ? 670 HIS A CB  1 
ATOM   5174  C  CG  . HIS A 1 670 ? 205.999 205.108 138.089 1.00 89.76  ? 670 HIS A CG  1 
ATOM   5175  N  ND1 . HIS A 1 670 ? 205.288 205.668 139.129 1.00 88.70  ? 670 HIS A ND1 1 
ATOM   5176  C  CD2 . HIS A 1 670 ? 205.202 205.197 136.999 1.00 90.78  ? 670 HIS A CD2 1 
ATOM   5177  C  CE1 . HIS A 1 670 ? 204.114 206.080 138.686 1.00 90.23  ? 670 HIS A CE1 1 
ATOM   5178  N  NE2 . HIS A 1 670 ? 204.036 205.806 137.397 1.00 94.05  ? 670 HIS A NE2 1 
ATOM   5179  N  N   . GLN A 1 671 ? 206.375 201.840 140.048 1.00 80.96  ? 671 GLN A N   1 
ATOM   5180  C  CA  . GLN A 1 671 ? 205.187 201.087 140.422 1.00 79.59  ? 671 GLN A CA  1 
ATOM   5181  C  C   . GLN A 1 671 ? 204.963 201.011 141.928 1.00 75.90  ? 671 GLN A C   1 
ATOM   5182  O  O   . GLN A 1 671 ? 203.809 200.953 142.362 1.00 72.66  ? 671 GLN A O   1 
ATOM   5183  C  CB  . GLN A 1 671 ? 205.269 199.670 139.851 1.00 83.44  ? 671 GLN A CB  1 
ATOM   5184  C  CG  . GLN A 1 671 ? 204.812 199.546 138.408 1.00 86.08  ? 671 GLN A CG  1 
ATOM   5185  C  CD  . GLN A 1 671 ? 203.312 199.380 138.283 1.00 84.64  ? 671 GLN A CD  1 
ATOM   5186  O  OE1 . GLN A 1 671 ? 202.541 200.095 138.918 1.00 83.52  ? 671 GLN A OE1 1 
ATOM   5187  N  NE2 . GLN A 1 671 ? 202.889 198.433 137.455 1.00 82.02  ? 671 GLN A NE2 1 
ATOM   5188  N  N   . LEU A 1 672 ? 206.020 201.013 142.739 1.00 76.20  ? 672 LEU A N   1 
ATOM   5189  C  CA  . LEU A 1 672 ? 205.883 200.666 144.146 1.00 72.14  ? 672 LEU A CA  1 
ATOM   5190  C  C   . LEU A 1 672 ? 206.323 201.808 145.053 1.00 72.64  ? 672 LEU A C   1 
ATOM   5191  O  O   . LEU A 1 672 ? 207.265 202.549 144.751 1.00 76.89  ? 672 LEU A O   1 
ATOM   5192  C  CB  . LEU A 1 672 ? 206.674 199.399 144.480 1.00 72.65  ? 672 LEU A CB  1 
ATOM   5193  C  CG  . LEU A 1 672 ? 208.192 199.445 144.366 1.00 81.71  ? 672 LEU A CG  1 
ATOM   5194  C  CD1 . LEU A 1 672 ? 208.815 199.566 145.741 1.00 81.36  ? 672 LEU A CD1 1 
ATOM   5195  C  CD2 . LEU A 1 672 ? 208.692 198.203 143.668 1.00 82.13  ? 672 LEU A CD2 1 
ATOM   5196  N  N   . THR A 1 673 ? 205.615 201.942 146.174 1.00 67.84  ? 673 THR A N   1 
ATOM   5197  C  CA  . THR A 1 673 ? 205.924 202.920 147.204 1.00 62.14  ? 673 THR A CA  1 
ATOM   5198  C  C   . THR A 1 673 ? 205.995 202.228 148.558 1.00 55.22  ? 673 THR A C   1 
ATOM   5199  O  O   . THR A 1 673 ? 205.435 201.150 148.759 1.00 58.34  ? 673 THR A O   1 
ATOM   5200  C  CB  . THR A 1 673 ? 204.882 204.044 147.267 1.00 61.02  ? 673 THR A CB  1 
ATOM   5201  O  OG1 . THR A 1 673 ? 203.825 203.663 148.155 1.00 59.78  ? 673 THR A OG1 1 
ATOM   5202  C  CG2 . THR A 1 673 ? 204.300 204.329 145.891 1.00 61.28  ? 673 THR A CG2 1 
ATOM   5203  N  N   . VAL A 1 674 ? 206.690 202.867 149.488 1.00 49.55  ? 674 VAL A N   1 
ATOM   5204  C  CA  . VAL A 1 674 ? 206.873 202.357 150.837 1.00 48.09  ? 674 VAL A CA  1 
ATOM   5205  C  C   . VAL A 1 674 ? 206.513 203.448 151.834 1.00 52.19  ? 674 VAL A C   1 
ATOM   5206  O  O   . VAL A 1 674 ? 206.831 204.623 151.635 1.00 58.07  ? 674 VAL A O   1 
ATOM   5207  C  CB  . VAL A 1 674 ? 208.316 201.868 151.055 1.00 51.27  ? 674 VAL A CB  1 
ATOM   5208  C  CG1 . VAL A 1 674 ? 208.555 200.601 150.286 1.00 51.55  ? 674 VAL A CG1 1 
ATOM   5209  C  CG2 . VAL A 1 674 ? 209.299 202.922 150.613 1.00 59.41  ? 674 VAL A CG2 1 
ATOM   5210  N  N   . GLU A 1 675 ? 205.842 203.060 152.914 1.00 48.37  ? 675 GLU A N   1 
ATOM   5211  C  CA  . GLU A 1 675 ? 205.341 204.005 153.902 1.00 47.44  ? 675 GLU A CA  1 
ATOM   5212  C  C   . GLU A 1 675 ? 206.135 203.894 155.194 1.00 45.04  ? 675 GLU A C   1 
ATOM   5213  O  O   . GLU A 1 675 ? 206.362 202.792 155.697 1.00 52.16  ? 675 GLU A O   1 
ATOM   5214  C  CB  . GLU A 1 675 ? 203.858 203.776 154.177 1.00 48.41  ? 675 GLU A CB  1 
ATOM   5215  C  CG  . GLU A 1 675 ? 203.021 203.776 152.929 1.00 53.39  ? 675 GLU A CG  1 
ATOM   5216  C  CD  . GLU A 1 675 ? 201.638 203.220 153.156 1.00 60.60  ? 675 GLU A CD  1 
ATOM   5217  O  OE1 . GLU A 1 675 ? 201.364 202.741 154.275 1.00 61.36  ? 675 GLU A OE1 1 
ATOM   5218  O  OE2 . GLU A 1 675 ? 200.820 203.260 152.212 1.00 66.03  ? 675 GLU A OE2 1 
ATOM   5219  N  N   . ILE A 1 676 ? 206.543 205.037 155.728 1.00 41.51  ? 676 ILE A N   1 
ATOM   5220  C  CA  . ILE A 1 676 ? 207.364 205.109 156.926 1.00 47.58  ? 676 ILE A CA  1 
ATOM   5221  C  C   . ILE A 1 676 ? 206.715 206.073 157.907 1.00 59.11  ? 676 ILE A C   1 
ATOM   5222  O  O   . ILE A 1 676 ? 206.284 207.166 157.523 1.00 62.63  ? 676 ILE A O   1 
ATOM   5223  C  CB  . ILE A 1 676 ? 208.800 205.551 156.589 1.00 51.62  ? 676 ILE A CB  1 
ATOM   5224  C  CG1 . ILE A 1 676 ? 209.491 204.491 155.741 1.00 53.48  ? 676 ILE A CG1 1 
ATOM   5225  C  CG2 . ILE A 1 676 ? 209.593 205.812 157.850 1.00 64.17  ? 676 ILE A CG2 1 
ATOM   5226  C  CD1 . ILE A 1 676 ? 209.344 204.693 154.261 1.00 52.41  ? 676 ILE A CD1 1 
ATOM   5227  N  N   . THR A 1 677 ? 206.649 205.672 159.173 1.00 63.84  ? 677 THR A N   1 
ATOM   5228  C  CA  . THR A 1 677 ? 205.962 206.436 160.206 1.00 67.16  ? 677 THR A CA  1 
ATOM   5229  C  C   . THR A 1 677 ? 206.711 207.688 160.631 1.00 72.43  ? 677 THR A C   1 
ATOM   5230  O  O   . THR A 1 677 ? 206.181 208.452 161.445 1.00 74.48  ? 677 THR A O   1 
ATOM   5231  C  CB  . THR A 1 677 ? 205.716 205.563 161.436 1.00 70.73  ? 677 THR A CB  1 
ATOM   5232  O  OG1 . THR A 1 677 ? 204.874 206.264 162.358 1.00 75.28  ? 677 THR A OG1 1 
ATOM   5233  C  CG2 . THR A 1 677 ? 207.031 205.232 162.119 1.00 76.42  ? 677 THR A CG2 1 
ATOM   5234  N  N   . GLU A 1 678 ? 207.941 207.876 160.157 1.00 73.68  ? 678 GLU A N   1 
ATOM   5235  C  CA  . GLU A 1 678 ? 208.755 209.064 160.407 1.00 79.54  ? 678 GLU A CA  1 
ATOM   5236  C  C   . GLU A 1 678 ? 209.270 209.085 161.842 1.00 79.89  ? 678 GLU A C   1 
ATOM   5237  O  O   . GLU A 1 678 ? 210.221 209.804 162.161 1.00 80.24  ? 678 GLU A O   1 
ATOM   5238  C  CB  . GLU A 1 678 ? 207.948 210.328 160.074 1.00 78.42  ? 678 GLU A CB  1 
ATOM   5239  C  CG  . GLU A 1 678 ? 208.378 211.617 160.762 1.00 79.18  ? 678 GLU A CG  1 
ATOM   5240  C  CD  . GLU A 1 678 ? 207.803 211.754 162.162 1.00 81.75  ? 678 GLU A CD  1 
ATOM   5241  O  OE1 . GLU A 1 678 ? 206.918 210.951 162.522 1.00 83.66  ? 678 GLU A OE1 1 
ATOM   5242  O  OE2 . GLU A 1 678 ? 208.244 212.657 162.903 1.00 82.61  ? 678 GLU A OE2 1 
ATOM   5243  N  N   . SER A 1 679 ? 208.716 208.231 162.696 1.00 78.94  ? 679 SER A N   1 
ATOM   5244  C  CA  . SER A 1 679 ? 209.284 208.077 164.026 1.00 81.86  ? 679 SER A CA  1 
ATOM   5245  C  C   . SER A 1 679 ? 210.642 207.402 163.952 1.00 88.08  ? 679 SER A C   1 
ATOM   5246  O  O   . SER A 1 679 ? 211.570 207.788 164.668 1.00 89.61  ? 679 SER A O   1 
ATOM   5247  C  CB  . SER A 1 679 ? 208.340 207.279 164.920 1.00 85.64  ? 679 SER A CB  1 
ATOM   5248  O  OG  . SER A 1 679 ? 209.004 206.846 166.094 1.00 93.27  ? 679 SER A OG  1 
ATOM   5249  N  N   . MET A 1 680 ? 210.771 206.388 163.096 1.00 90.75  ? 680 MET A N   1 
ATOM   5250  C  CA  . MET A 1 680 ? 212.054 205.721 162.925 1.00 92.64  ? 680 MET A CA  1 
ATOM   5251  C  C   . MET A 1 680 ? 212.946 206.449 161.933 1.00 94.28  ? 680 MET A C   1 
ATOM   5252  O  O   . MET A 1 680 ? 214.151 206.184 161.882 1.00 97.32  ? 680 MET A O   1 
ATOM   5253  C  CB  . MET A 1 680 ? 211.849 204.275 162.474 1.00 92.68  ? 680 MET A CB  1 
ATOM   5254  C  CG  . MET A 1 680 ? 210.934 204.107 161.272 1.00 88.87  ? 680 MET A CG  1 
ATOM   5255  S  SD  . MET A 1 680 ? 210.177 202.470 161.247 1.00 86.07  ? 680 MET A SD  1 
ATOM   5256  C  CE  . MET A 1 680 ? 209.135 202.593 159.801 1.00 62.63  ? 680 MET A CE  1 
ATOM   5257  N  N   . MET A 1 681 ? 212.386 207.371 161.151 1.00 91.99  ? 681 MET A N   1 
ATOM   5258  C  CA  . MET A 1 681 ? 213.190 208.085 160.168 1.00 93.34  ? 681 MET A CA  1 
ATOM   5259  C  C   . MET A 1 681 ? 214.197 209.008 160.839 1.00 99.16  ? 681 MET A C   1 
ATOM   5260  O  O   . MET A 1 681 ? 215.123 209.497 160.185 1.00 102.91 ? 681 MET A O   1 
ATOM   5261  C  CB  . MET A 1 681 ? 212.278 208.867 159.225 1.00 91.20  ? 681 MET A CB  1 
ATOM   5262  C  CG  . MET A 1 681 ? 212.956 209.429 158.001 1.00 92.44  ? 681 MET A CG  1 
ATOM   5263  S  SD  . MET A 1 681 ? 211.817 210.449 157.054 1.00 97.01  ? 681 MET A SD  1 
ATOM   5264  C  CE  . MET A 1 681 ? 210.752 209.193 156.358 1.00 77.75  ? 681 MET A CE  1 
ATOM   5265  N  N   . MET A 1 682 ? 214.034 209.254 162.136 1.00 100.54 ? 682 MET A N   1 
ATOM   5266  C  CA  . MET A 1 682 ? 215.007 210.037 162.881 1.00 105.63 ? 682 MET A CA  1 
ATOM   5267  C  C   . MET A 1 682 ? 216.368 209.357 162.833 1.00 114.81 ? 682 MET A C   1 
ATOM   5268  O  O   . MET A 1 682 ? 216.472 208.128 162.822 1.00 113.67 ? 682 MET A O   1 
ATOM   5269  C  CB  . MET A 1 682 ? 214.563 210.198 164.333 1.00 105.95 ? 682 MET A CB  1 
ATOM   5270  C  CG  . MET A 1 682 ? 214.643 211.614 164.862 1.00 103.48 ? 682 MET A CG  1 
ATOM   5271  S  SD  . MET A 1 682 ? 213.624 212.750 163.910 1.00 105.69 ? 682 MET A SD  1 
ATOM   5272  C  CE  . MET A 1 682 ? 211.996 212.301 164.510 1.00 100.73 ? 682 MET A CE  1 
ATOM   5273  N  N   . GLU A 1 683 ? 217.423 210.174 162.800 1.00 120.10 ? 683 GLU A N   1 
ATOM   5274  C  CA  . GLU A 1 683 ? 218.771 209.631 162.666 1.00 123.90 ? 683 GLU A CA  1 
ATOM   5275  C  C   . GLU A 1 683 ? 219.128 208.725 163.840 1.00 127.58 ? 683 GLU A C   1 
ATOM   5276  O  O   . GLU A 1 683 ? 219.677 207.634 163.640 1.00 126.78 ? 683 GLU A O   1 
ATOM   5277  C  CB  . GLU A 1 683 ? 219.786 210.768 162.517 1.00 121.90 ? 683 GLU A CB  1 
ATOM   5278  C  CG  . GLU A 1 683 ? 219.850 211.748 163.683 1.00 122.63 ? 683 GLU A CG  1 
ATOM   5279  C  CD  . GLU A 1 683 ? 218.761 212.803 163.622 1.00 123.29 ? 683 GLU A CD  1 
ATOM   5280  O  OE1 . GLU A 1 683 ? 218.310 213.127 162.504 1.00 122.48 ? 683 GLU A OE1 1 
ATOM   5281  O  OE2 . GLU A 1 683 ? 218.355 213.304 164.692 1.00 124.09 ? 683 GLU A OE2 1 
ATOM   5282  N  N   . HIS A 1 684 ? 218.798 209.144 165.066 1.00 128.87 ? 684 HIS A N   1 
ATOM   5283  C  CA  . HIS A 1 684 ? 219.098 208.384 166.277 1.00 131.00 ? 684 HIS A CA  1 
ATOM   5284  C  C   . HIS A 1 684 ? 220.541 207.897 166.287 1.00 135.36 ? 684 HIS A C   1 
ATOM   5285  O  O   . HIS A 1 684 ? 221.466 208.664 166.576 1.00 133.31 ? 684 HIS A O   1 
ATOM   5286  C  CB  . HIS A 1 684 ? 218.144 207.195 166.419 1.00 129.01 ? 684 HIS A CB  1 
ATOM   5287  C  CG  . HIS A 1 684 ? 216.727 207.584 166.705 1.00 122.71 ? 684 HIS A CG  1 
ATOM   5288  N  ND1 . HIS A 1 684 ? 216.368 208.336 167.803 1.00 118.51 ? 684 HIS A ND1 1 
ATOM   5289  C  CD2 . HIS A 1 684 ? 215.577 207.315 166.042 1.00 117.17 ? 684 HIS A CD2 1 
ATOM   5290  C  CE1 . HIS A 1 684 ? 215.060 208.519 167.800 1.00 113.50 ? 684 HIS A CE1 1 
ATOM   5291  N  NE2 . HIS A 1 684 ? 214.556 207.909 166.743 1.00 114.46 ? 684 HIS A NE2 1 
ATOM   5292  N  N   . ASP A 1 685 ? 220.735 206.614 165.971 1.00 138.92 ? 685 ASP A N   1 
ATOM   5293  C  CA  . ASP A 1 685 ? 222.070 206.043 165.841 1.00 140.51 ? 685 ASP A CA  1 
ATOM   5294  C  C   . ASP A 1 685 ? 222.173 205.113 164.635 1.00 141.89 ? 685 ASP A C   1 
ATOM   5295  O  O   . ASP A 1 685 ? 223.145 204.356 164.528 1.00 142.59 ? 685 ASP A O   1 
ATOM   5296  C  CB  . ASP A 1 685 ? 222.467 205.291 167.116 1.00 139.85 ? 685 ASP A CB  1 
ATOM   5297  C  CG  . ASP A 1 685 ? 221.448 204.241 167.517 1.00 141.21 ? 685 ASP A CG  1 
ATOM   5298  O  OD1 . ASP A 1 685 ? 220.314 204.282 166.996 1.00 142.45 ? 685 ASP A OD1 1 
ATOM   5299  O  OD2 . ASP A 1 685 ? 221.782 203.376 168.354 1.00 142.31 ? 685 ASP A OD2 1 
ATOM   5300  N  N   . THR A 1 686 ? 221.197 205.150 163.729 1.00 139.35 ? 686 THR A N   1 
ATOM   5301  C  CA  . THR A 1 686 ? 221.174 204.294 162.548 1.00 133.51 ? 686 THR A CA  1 
ATOM   5302  C  C   . THR A 1 686 ? 221.439 205.043 161.253 1.00 129.36 ? 686 THR A C   1 
ATOM   5303  O  O   . THR A 1 686 ? 222.117 204.511 160.370 1.00 129.21 ? 686 THR A O   1 
ATOM   5304  C  CB  . THR A 1 686 ? 219.823 203.578 162.436 1.00 124.68 ? 686 THR A CB  1 
ATOM   5305  O  OG1 . THR A 1 686 ? 218.785 204.546 162.235 1.00 121.15 ? 686 THR A OG1 1 
ATOM   5306  C  CG2 . THR A 1 686 ? 219.534 202.786 163.703 1.00 121.38 ? 686 THR A CG2 1 
ATOM   5307  N  N   . GLU A 1 687 ? 220.914 206.264 161.119 1.00 125.54 ? 687 GLU A N   1 
ATOM   5308  C  CA  . GLU A 1 687 ? 221.086 207.079 159.915 1.00 122.90 ? 687 GLU A CA  1 
ATOM   5309  C  C   . GLU A 1 687 ? 220.570 206.350 158.675 1.00 117.04 ? 687 GLU A C   1 
ATOM   5310  O  O   . GLU A 1 687 ? 221.302 206.113 157.712 1.00 116.27 ? 687 GLU A O   1 
ATOM   5311  C  CB  . GLU A 1 687 ? 222.546 207.500 159.737 1.00 124.32 ? 687 GLU A CB  1 
ATOM   5312  C  CG  . GLU A 1 687 ? 222.734 208.762 158.914 1.00 123.68 ? 687 GLU A CG  1 
ATOM   5313  C  CD  . GLU A 1 687 ? 224.192 209.149 158.773 1.00 125.78 ? 687 GLU A CD  1 
ATOM   5314  O  OE1 . GLU A 1 687 ? 225.019 208.261 158.478 1.00 122.55 ? 687 GLU A OE1 1 
ATOM   5315  O  OE2 . GLU A 1 687 ? 224.512 210.342 158.957 1.00 126.10 ? 687 GLU A OE2 1 
ATOM   5316  N  N   . ILE A 1 688 ? 219.285 206.007 158.697 1.00 110.81 ? 688 ILE A N   1 
ATOM   5317  C  CA  . ILE A 1 688 ? 218.661 205.339 157.563 1.00 109.21 ? 688 ILE A CA  1 
ATOM   5318  C  C   . ILE A 1 688 ? 218.284 206.387 156.528 1.00 108.49 ? 688 ILE A C   1 
ATOM   5319  O  O   . ILE A 1 688 ? 217.611 206.087 155.535 1.00 108.07 ? 688 ILE A O   1 
ATOM   5320  C  CB  . ILE A 1 688 ? 217.437 204.517 157.995 1.00 105.84 ? 688 ILE A CB  1 
ATOM   5321  C  CG1 . ILE A 1 688 ? 216.646 205.256 159.070 1.00 101.53 ? 688 ILE A CG1 1 
ATOM   5322  C  CG2 . ILE A 1 688 ? 217.871 203.158 158.508 1.00 106.46 ? 688 ILE A CG2 1 
ATOM   5323  C  CD1 . ILE A 1 688 ? 215.490 204.457 159.609 1.00 95.27  ? 688 ILE A CD1 1 
ATOM   5324  N  N   . PHE A 1 689 ? 218.712 207.629 156.762 1.00 110.47 ? 689 PHE A N   1 
ATOM   5325  C  CA  . PHE A 1 689 ? 218.512 208.672 155.766 1.00 113.29 ? 689 PHE A CA  1 
ATOM   5326  C  C   . PHE A 1 689 ? 219.191 208.307 154.457 1.00 112.77 ? 689 PHE A C   1 
ATOM   5327  O  O   . PHE A 1 689 ? 218.624 208.509 153.380 1.00 110.19 ? 689 PHE A O   1 
ATOM   5328  C  CB  . PHE A 1 689 ? 219.039 210.011 156.279 1.00 113.84 ? 689 PHE A CB  1 
ATOM   5329  C  CG  . PHE A 1 689 ? 218.090 210.730 157.185 1.00 112.25 ? 689 PHE A CG  1 
ATOM   5330  C  CD1 . PHE A 1 689 ? 216.904 211.244 156.693 1.00 107.80 ? 689 PHE A CD1 1 
ATOM   5331  C  CD2 . PHE A 1 689 ? 218.387 210.904 158.526 1.00 114.84 ? 689 PHE A CD2 1 
ATOM   5332  C  CE1 . PHE A 1 689 ? 216.027 211.912 157.522 1.00 104.23 ? 689 PHE A CE1 1 
ATOM   5333  C  CE2 . PHE A 1 689 ? 217.514 211.573 159.362 1.00 114.10 ? 689 PHE A CE2 1 
ATOM   5334  C  CZ  . PHE A 1 689 ? 216.333 212.078 158.859 1.00 108.10 ? 689 PHE A CZ  1 
ATOM   5335  N  N   . LYS A 1 690 ? 220.408 207.770 154.529 1.00 114.44 ? 690 LYS A N   1 
ATOM   5336  C  CA  . LYS A 1 690 ? 221.092 207.367 153.307 1.00 114.34 ? 690 LYS A CA  1 
ATOM   5337  C  C   . LYS A 1 690 ? 220.318 206.269 152.591 1.00 112.45 ? 690 LYS A C   1 
ATOM   5338  O  O   . LYS A 1 690 ? 220.232 206.263 151.359 1.00 113.29 ? 690 LYS A O   1 
ATOM   5339  C  CB  . LYS A 1 690 ? 222.523 206.923 153.620 1.00 117.23 ? 690 LYS A CB  1 
ATOM   5340  C  CG  . LYS A 1 690 ? 222.637 205.724 154.549 1.00 119.56 ? 690 LYS A CG  1 
ATOM   5341  C  CD  . LYS A 1 690 ? 223.877 205.821 155.423 1.00 124.72 ? 690 LYS A CD  1 
ATOM   5342  C  CE  . LYS A 1 690 ? 225.139 205.931 154.583 1.00 124.44 ? 690 LYS A CE  1 
ATOM   5343  N  NZ  . LYS A 1 690 ? 226.338 206.217 155.419 1.00 124.04 ? 690 LYS A NZ  1 
ATOM   5344  N  N   . ARG A 1 691 ? 219.725 205.344 153.348 1.00 110.98 ? 691 ARG A N   1 
ATOM   5345  C  CA  . ARG A 1 691 ? 218.967 204.262 152.730 1.00 112.16 ? 691 ARG A CA  1 
ATOM   5346  C  C   . ARG A 1 691 ? 217.708 204.781 152.050 1.00 108.22 ? 691 ARG A C   1 
ATOM   5347  O  O   . ARG A 1 691 ? 217.399 204.384 150.920 1.00 108.30 ? 691 ARG A O   1 
ATOM   5348  C  CB  . ARG A 1 691 ? 218.622 203.206 153.776 1.00 112.50 ? 691 ARG A CB  1 
ATOM   5349  C  CG  . ARG A 1 691 ? 219.840 202.607 154.447 1.00 111.09 ? 691 ARG A CG  1 
ATOM   5350  C  CD  . ARG A 1 691 ? 219.449 201.625 155.525 1.00 110.37 ? 691 ARG A CD  1 
ATOM   5351  N  NE  . ARG A 1 691 ? 220.602 200.884 156.020 1.00 110.13 ? 691 ARG A NE  1 
ATOM   5352  C  CZ  . ARG A 1 691 ? 221.386 201.293 157.007 1.00 113.52 ? 691 ARG A CZ  1 
ATOM   5353  N  NH1 . ARG A 1 691 ? 221.172 202.440 157.631 1.00 113.82 ? 691 ARG A NH1 1 
ATOM   5354  N  NH2 . ARG A 1 691 ? 222.412 200.532 157.378 1.00 118.93 ? 691 ARG A NH2 1 
ATOM   5355  N  N   . ILE A 1 692 ? 216.965 205.664 152.716 1.00 105.10 ? 692 ILE A N   1 
ATOM   5356  C  CA  . ILE A 1 692 ? 215.763 206.186 152.078 1.00 106.10 ? 692 ILE A CA  1 
ATOM   5357  C  C   . ILE A 1 692 ? 216.125 207.088 150.903 1.00 110.21 ? 692 ILE A C   1 
ATOM   5358  O  O   . ILE A 1 692 ? 215.391 207.147 149.910 1.00 108.69 ? 692 ILE A O   1 
ATOM   5359  C  CB  . ILE A 1 692 ? 214.863 206.896 153.107 1.00 104.97 ? 692 ILE A CB  1 
ATOM   5360  C  CG1 . ILE A 1 692 ? 215.585 208.078 153.750 1.00 110.24 ? 692 ILE A CG1 1 
ATOM   5361  C  CG2 . ILE A 1 692 ? 214.403 205.911 154.166 1.00 101.31 ? 692 ILE A CG2 1 
ATOM   5362  C  CD1 . ILE A 1 692 ? 214.694 208.936 154.621 1.00 110.51 ? 692 ILE A CD1 1 
ATOM   5363  N  N   . GLN A 1 693 ? 217.265 207.783 150.973 1.00 112.29 ? 693 GLN A N   1 
ATOM   5364  C  CA  . GLN A 1 693 ? 217.728 208.569 149.833 1.00 109.77 ? 693 GLN A CA  1 
ATOM   5365  C  C   . GLN A 1 693 ? 218.083 207.672 148.655 1.00 107.64 ? 693 GLN A C   1 
ATOM   5366  O  O   . GLN A 1 693 ? 217.771 207.996 147.504 1.00 106.60 ? 693 GLN A O   1 
ATOM   5367  C  CB  . GLN A 1 693 ? 218.928 209.424 150.236 1.00 108.35 ? 693 GLN A CB  1 
ATOM   5368  C  CG  . GLN A 1 693 ? 218.564 210.703 150.973 1.00 108.88 ? 693 GLN A CG  1 
ATOM   5369  C  CD  . GLN A 1 693 ? 218.445 211.898 150.047 1.00 105.08 ? 693 GLN A CD  1 
ATOM   5370  O  OE1 . GLN A 1 693 ? 218.189 211.749 148.852 1.00 105.47 ? 693 GLN A OE1 1 
ATOM   5371  N  NE2 . GLN A 1 693 ? 218.633 213.092 150.596 1.00 95.82  ? 693 GLN A NE2 1 
ATOM   5372  N  N   . ILE A 1 694 ? 218.736 206.542 148.923 1.00 108.47 ? 694 ILE A N   1 
ATOM   5373  C  CA  . ILE A 1 694 ? 219.026 205.581 147.866 1.00 106.10 ? 694 ILE A CA  1 
ATOM   5374  C  C   . ILE A 1 694 ? 217.732 205.072 147.253 1.00 99.24  ? 694 ILE A C   1 
ATOM   5375  O  O   . ILE A 1 694 ? 217.589 205.004 146.025 1.00 97.77  ? 694 ILE A O   1 
ATOM   5376  C  CB  . ILE A 1 694 ? 219.886 204.429 148.416 1.00 109.23 ? 694 ILE A CB  1 
ATOM   5377  C  CG1 . ILE A 1 694 ? 221.335 204.886 148.600 1.00 111.65 ? 694 ILE A CG1 1 
ATOM   5378  C  CG2 . ILE A 1 694 ? 219.819 203.221 147.498 1.00 104.89 ? 694 ILE A CG2 1 
ATOM   5379  C  CD1 . ILE A 1 694 ? 222.138 204.008 149.535 1.00 108.41 ? 694 ILE A CD1 1 
ATOM   5380  N  N   . LEU A 1 695 ? 216.761 204.728 148.100 1.00 96.91  ? 695 LEU A N   1 
ATOM   5381  C  CA  . LEU A 1 695 ? 215.482 204.244 147.599 1.00 96.26  ? 695 LEU A CA  1 
ATOM   5382  C  C   . LEU A 1 695 ? 214.815 205.289 146.720 1.00 92.60  ? 695 LEU A C   1 
ATOM   5383  O  O   . LEU A 1 695 ? 214.228 204.960 145.684 1.00 91.92  ? 695 LEU A O   1 
ATOM   5384  C  CB  . LEU A 1 695 ? 214.568 203.858 148.760 1.00 100.02 ? 695 LEU A CB  1 
ATOM   5385  C  CG  . LEU A 1 695 ? 214.950 202.618 149.568 1.00 105.45 ? 695 LEU A CG  1 
ATOM   5386  C  CD1 . LEU A 1 695 ? 213.878 202.302 150.599 1.00 102.71 ? 695 LEU A CD1 1 
ATOM   5387  C  CD2 . LEU A 1 695 ? 215.181 201.429 148.651 1.00 102.31 ? 695 LEU A CD2 1 
ATOM   5388  N  N   . ARG A 1 696 ? 214.891 206.556 147.123 1.00 92.72  ? 696 ARG A N   1 
ATOM   5389  C  CA  . ARG A 1 696 ? 214.352 207.622 146.292 1.00 94.63  ? 696 ARG A CA  1 
ATOM   5390  C  C   . ARG A 1 696 ? 215.091 207.695 144.965 1.00 98.75  ? 696 ARG A C   1 
ATOM   5391  O  O   . ARG A 1 696 ? 214.478 207.908 143.912 1.00 97.63  ? 696 ARG A O   1 
ATOM   5392  C  CB  . ARG A 1 696 ? 214.441 208.956 147.029 1.00 96.15  ? 696 ARG A CB  1 
ATOM   5393  C  CG  . ARG A 1 696 ? 213.329 209.174 148.028 1.00 93.48  ? 696 ARG A CG  1 
ATOM   5394  C  CD  . ARG A 1 696 ? 211.990 209.221 147.327 1.00 88.75  ? 696 ARG A CD  1 
ATOM   5395  N  NE  . ARG A 1 696 ? 212.033 210.062 146.140 1.00 89.17  ? 696 ARG A NE  1 
ATOM   5396  C  CZ  . ARG A 1 696 ? 211.164 209.987 145.144 1.00 86.22  ? 696 ARG A CZ  1 
ATOM   5397  N  NH1 . ARG A 1 696 ? 210.173 209.112 145.159 1.00 80.39  ? 696 ARG A NH1 1 
ATOM   5398  N  NH2 . ARG A 1 696 ? 211.293 210.808 144.107 1.00 88.19  ? 696 ARG A NH2 1 
ATOM   5399  N  N   . ASP A 1 697 ? 216.411 207.516 144.998 1.00 102.33 ? 697 ASP A N   1 
ATOM   5400  C  CA  . ASP A 1 697 ? 217.200 207.576 143.774 1.00 102.87 ? 697 ASP A CA  1 
ATOM   5401  C  C   . ASP A 1 697 ? 216.827 206.458 142.813 1.00 101.75 ? 697 ASP A C   1 
ATOM   5402  O  O   . ASP A 1 697 ? 216.882 206.648 141.593 1.00 102.60 ? 697 ASP A O   1 
ATOM   5403  C  CB  . ASP A 1 697 ? 218.691 207.520 144.106 1.00 101.86 ? 697 ASP A CB  1 
ATOM   5404  C  CG  . ASP A 1 697 ? 219.182 208.777 144.798 1.00 103.06 ? 697 ASP A CG  1 
ATOM   5405  O  OD1 . ASP A 1 697 ? 218.434 209.777 144.819 1.00 102.09 ? 697 ASP A OD1 1 
ATOM   5406  O  OD2 . ASP A 1 697 ? 220.316 208.765 145.320 1.00 102.65 ? 697 ASP A OD2 1 
ATOM   5407  N  N   . MET A 1 698 ? 216.445 205.292 143.331 1.00 99.07  ? 698 MET A N   1 
ATOM   5408  C  CA  . MET A 1 698 ? 216.078 204.174 142.473 1.00 96.59  ? 698 MET A CA  1 
ATOM   5409  C  C   . MET A 1 698 ? 214.592 204.156 142.133 1.00 92.87  ? 698 MET A C   1 
ATOM   5410  O  O   . MET A 1 698 ? 214.117 203.187 141.533 1.00 88.98  ? 698 MET A O   1 
ATOM   5411  C  CB  . MET A 1 698 ? 216.498 202.844 143.106 1.00 98.52  ? 698 MET A CB  1 
ATOM   5412  C  CG  . MET A 1 698 ? 216.174 202.710 144.569 1.00 101.40 ? 698 MET A CG  1 
ATOM   5413  S  SD  . MET A 1 698 ? 216.454 201.056 145.231 1.00 110.34 ? 698 MET A SD  1 
ATOM   5414  C  CE  . MET A 1 698 ? 217.667 200.420 144.077 1.00 102.73 ? 698 MET A CE  1 
ATOM   5415  N  N   . GLY A 1 699 ? 213.849 205.196 142.502 1.00 92.03  ? 699 GLY A N   1 
ATOM   5416  C  CA  . GLY A 1 699 ? 212.506 205.391 142.002 1.00 88.91  ? 699 GLY A CA  1 
ATOM   5417  C  C   . GLY A 1 699 ? 211.392 204.913 142.906 1.00 88.26  ? 699 GLY A C   1 
ATOM   5418  O  O   . GLY A 1 699 ? 210.219 205.095 142.557 1.00 86.16  ? 699 GLY A O   1 
ATOM   5419  N  N   . VAL A 1 700 ? 211.713 204.312 144.050 1.00 90.38  ? 700 VAL A N   1 
ATOM   5420  C  CA  . VAL A 1 700 ? 210.680 203.853 144.968 1.00 79.73  ? 700 VAL A CA  1 
ATOM   5421  C  C   . VAL A 1 700 ? 209.958 205.057 145.553 1.00 73.11  ? 700 VAL A C   1 
ATOM   5422  O  O   . VAL A 1 700 ? 210.591 206.006 146.033 1.00 79.63  ? 700 VAL A O   1 
ATOM   5423  C  CB  . VAL A 1 700 ? 211.295 202.988 146.075 1.00 80.22  ? 700 VAL A CB  1 
ATOM   5424  C  CG1 . VAL A 1 700 ? 210.255 202.655 147.123 1.00 73.79  ? 700 VAL A CG1 1 
ATOM   5425  C  CG2 . VAL A 1 700 ? 211.894 201.724 145.486 1.00 84.25  ? 700 VAL A CG2 1 
ATOM   5426  N  N   . GLY A 1 701 ? 208.632 205.031 145.515 1.00 63.58  ? 701 GLY A N   1 
ATOM   5427  C  CA  . GLY A 1 701 ? 207.871 206.084 146.153 1.00 65.64  ? 701 GLY A CA  1 
ATOM   5428  C  C   . GLY A 1 701 ? 208.001 206.036 147.663 1.00 68.10  ? 701 GLY A C   1 
ATOM   5429  O  O   . GLY A 1 701 ? 208.205 204.982 148.262 1.00 70.12  ? 701 GLY A O   1 
ATOM   5430  N  N   . LEU A 1 702 ? 207.862 207.199 148.291 1.00 63.83  ? 702 LEU A N   1 
ATOM   5431  C  CA  . LEU A 1 702 ? 207.993 207.341 149.734 1.00 57.08  ? 702 LEU A CA  1 
ATOM   5432  C  C   . LEU A 1 702 ? 206.691 207.868 150.314 1.00 51.19  ? 702 LEU A C   1 
ATOM   5433  O  O   . LEU A 1 702 ? 205.958 208.597 149.645 1.00 55.26  ? 702 LEU A O   1 
ATOM   5434  C  CB  . LEU A 1 702 ? 209.134 208.285 150.081 1.00 60.57  ? 702 LEU A CB  1 
ATOM   5435  C  CG  . LEU A 1 702 ? 210.457 207.687 150.544 1.00 65.69  ? 702 LEU A CG  1 
ATOM   5436  C  CD1 . LEU A 1 702 ? 210.330 207.158 151.950 1.00 66.38  ? 702 LEU A CD1 1 
ATOM   5437  C  CD2 . LEU A 1 702 ? 210.905 206.584 149.605 1.00 68.46  ? 702 LEU A CD2 1 
ATOM   5438  N  N   . SER A 1 703 ? 206.391 207.485 151.546 1.00 45.09  ? 703 SER A N   1 
ATOM   5439  C  CA  . SER A 1 703 ? 205.225 208.022 152.225 1.00 44.36  ? 703 SER A CA  1 
ATOM   5440  C  C   . SER A 1 703 ? 205.546 208.278 153.688 1.00 47.81  ? 703 SER A C   1 
ATOM   5441  O  O   . SER A 1 703 ? 206.319 207.546 154.309 1.00 56.09  ? 703 SER A O   1 
ATOM   5442  C  CB  . SER A 1 703 ? 204.034 207.090 152.123 1.00 46.70  ? 703 SER A CB  1 
ATOM   5443  O  OG  . SER A 1 703 ? 202.907 207.667 152.751 1.00 50.51  ? 703 SER A OG  1 
ATOM   5444  N  N   . VAL A 1 704 ? 204.936 209.326 154.233 1.00 42.05  ? 704 VAL A N   1 
ATOM   5445  C  CA  . VAL A 1 704 ? 205.099 209.726 155.617 1.00 40.05  ? 704 VAL A CA  1 
ATOM   5446  C  C   . VAL A 1 704 ? 203.718 209.917 156.226 1.00 39.37  ? 704 VAL A C   1 
ATOM   5447  O  O   . VAL A 1 704 ? 202.701 209.747 155.563 1.00 44.25  ? 704 VAL A O   1 
ATOM   5448  C  CB  . VAL A 1 704 ? 205.942 211.004 155.766 1.00 51.58  ? 704 VAL A CB  1 
ATOM   5449  C  CG1 . VAL A 1 704 ? 207.149 210.944 154.865 1.00 56.44  ? 704 VAL A CG1 1 
ATOM   5450  C  CG2 . VAL A 1 704 ? 205.106 212.226 155.433 1.00 52.04  ? 704 VAL A CG2 1 
ATOM   5451  N  N   . ASP A 1 705 ? 203.695 210.260 157.509 1.00 43.35  ? 705 ASP A N   1 
ATOM   5452  C  CA  . ASP A 1 705 ? 202.445 210.412 158.237 1.00 50.01  ? 705 ASP A CA  1 
ATOM   5453  C  C   . ASP A 1 705 ? 202.445 211.677 159.082 1.00 58.72  ? 705 ASP A C   1 
ATOM   5454  O  O   . ASP A 1 705 ? 201.398 212.288 159.303 1.00 60.84  ? 705 ASP A O   1 
ATOM   5455  C  CB  . ASP A 1 705 ? 202.205 209.191 159.116 1.00 55.96  ? 705 ASP A CB  1 
ATOM   5456  C  CG  . ASP A 1 705 ? 200.881 209.244 159.833 1.00 59.73  ? 705 ASP A CG  1 
ATOM   5457  O  OD1 . ASP A 1 705 ? 199.917 209.789 159.257 1.00 58.34  ? 705 ASP A OD1 1 
ATOM   5458  O  OD2 . ASP A 1 705 ? 200.803 208.741 160.972 1.00 61.91  ? 705 ASP A OD2 1 
ATOM   5459  N  N   . ASP A 1 706 ? 203.620 212.068 159.560 1.00 64.57  ? 706 ASP A N   1 
ATOM   5460  C  CA  . ASP A 1 706 ? 203.810 213.289 160.322 1.00 66.03  ? 706 ASP A CA  1 
ATOM   5461  C  C   . ASP A 1 706 ? 205.066 213.982 159.818 1.00 67.61  ? 706 ASP A C   1 
ATOM   5462  O  O   . ASP A 1 706 ? 205.923 213.365 159.183 1.00 70.73  ? 706 ASP A O   1 
ATOM   5463  C  CB  . ASP A 1 706 ? 203.940 213.009 161.822 1.00 66.57  ? 706 ASP A CB  1 
ATOM   5464  C  CG  . ASP A 1 706 ? 202.628 213.146 162.561 1.00 72.88  ? 706 ASP A CG  1 
ATOM   5465  O  OD1 . ASP A 1 706 ? 202.655 213.261 163.805 1.00 76.65  ? 706 ASP A OD1 1 
ATOM   5466  O  OD2 . ASP A 1 706 ? 201.570 213.134 161.905 1.00 71.36  ? 706 ASP A OD2 1 
ATOM   5467  N  N   . PHE A 1 707 ? 205.168 215.279 160.095 1.00 64.77  ? 707 PHE A N   1 
ATOM   5468  C  CA  . PHE A 1 707 ? 206.374 216.004 159.714 1.00 66.20  ? 707 PHE A CA  1 
ATOM   5469  C  C   . PHE A 1 707 ? 207.500 215.783 160.713 1.00 70.54  ? 707 PHE A C   1 
ATOM   5470  O  O   . PHE A 1 707 ? 208.585 215.327 160.342 1.00 73.04  ? 707 PHE A O   1 
ATOM   5471  C  CB  . PHE A 1 707 ? 206.077 217.493 159.558 1.00 67.00  ? 707 PHE A CB  1 
ATOM   5472  C  CG  . PHE A 1 707 ? 204.991 217.799 158.565 1.00 74.65  ? 707 PHE A CG  1 
ATOM   5473  C  CD1 . PHE A 1 707 ? 204.630 216.875 157.602 1.00 74.05  ? 707 PHE A CD1 1 
ATOM   5474  C  CD2 . PHE A 1 707 ? 204.348 219.025 158.579 1.00 75.90  ? 707 PHE A CD2 1 
ATOM   5475  C  CE1 . PHE A 1 707 ? 203.641 217.158 156.682 1.00 71.44  ? 707 PHE A CE1 1 
ATOM   5476  C  CE2 . PHE A 1 707 ? 203.357 219.314 157.659 1.00 74.93  ? 707 PHE A CE2 1 
ATOM   5477  C  CZ  . PHE A 1 707 ? 203.005 218.381 156.709 1.00 73.38  ? 707 PHE A CZ  1 
ATOM   5478  N  N   . GLY A 1 708 ? 207.269 216.105 161.977 1.00 75.37  ? 708 GLY A N   1 
ATOM   5479  C  CA  . GLY A 1 708 ? 208.287 215.867 162.975 1.00 79.85  ? 708 GLY A CA  1 
ATOM   5480  C  C   . GLY A 1 708 ? 208.443 216.964 164.005 1.00 78.59  ? 708 GLY A C   1 
ATOM   5481  O  O   . GLY A 1 708 ? 207.457 217.522 164.493 1.00 77.06  ? 708 GLY A O   1 
ATOM   5482  N  N   . THR A 1 709 ? 209.693 217.260 164.358 1.00 79.15  ? 709 THR A N   1 
ATOM   5483  C  CA  . THR A 1 709 ? 209.964 218.217 165.421 1.00 81.00  ? 709 THR A CA  1 
ATOM   5484  C  C   . THR A 1 709 ? 209.626 219.640 165.004 1.00 80.57  ? 709 THR A C   1 
ATOM   5485  O  O   . THR A 1 709 ? 208.981 220.371 165.761 1.00 79.28  ? 709 THR A O   1 
ATOM   5486  C  CB  . THR A 1 709 ? 211.431 218.132 165.842 1.00 89.03  ? 709 THR A CB  1 
ATOM   5487  O  OG1 . THR A 1 709 ? 212.261 218.617 164.779 1.00 89.26  ? 709 THR A OG1 1 
ATOM   5488  C  CG2 . THR A 1 709 ? 211.813 216.693 166.155 1.00 84.18  ? 709 THR A CG2 1 
ATOM   5489  N  N   . GLY A 1 710 ? 210.046 220.047 163.810 1.00 81.19  ? 710 GLY A N   1 
ATOM   5490  C  CA  . GLY A 1 710 ? 209.847 221.414 163.371 1.00 77.72  ? 710 GLY A CA  1 
ATOM   5491  C  C   . GLY A 1 710 ? 210.346 221.670 161.967 1.00 74.16  ? 710 GLY A C   1 
ATOM   5492  O  O   . GLY A 1 710 ? 210.102 220.866 161.063 1.00 77.79  ? 710 GLY A O   1 
ATOM   5493  N  N   . PHE A 1 711 ? 211.041 222.792 161.768 1.00 70.63  ? 711 PHE A N   1 
ATOM   5494  C  CA  . PHE A 1 711 ? 211.564 223.102 160.443 1.00 71.45  ? 711 PHE A CA  1 
ATOM   5495  C  C   . PHE A 1 711 ? 212.497 222.020 159.931 1.00 69.93  ? 711 PHE A C   1 
ATOM   5496  O  O   . PHE A 1 711 ? 212.537 221.760 158.726 1.00 69.54  ? 711 PHE A O   1 
ATOM   5497  C  CB  . PHE A 1 711 ? 212.286 224.444 160.457 1.00 76.99  ? 711 PHE A CB  1 
ATOM   5498  C  CG  . PHE A 1 711 ? 211.369 225.619 160.477 1.00 80.13  ? 711 PHE A CG  1 
ATOM   5499  C  CD1 . PHE A 1 711 ? 210.158 225.567 159.824 1.00 78.21  ? 711 PHE A CD1 1 
ATOM   5500  C  CD2 . PHE A 1 711 ? 211.727 226.785 161.121 1.00 77.75  ? 711 PHE A CD2 1 
ATOM   5501  C  CE1 . PHE A 1 711 ? 209.318 226.643 159.825 1.00 76.30  ? 711 PHE A CE1 1 
ATOM   5502  C  CE2 . PHE A 1 711 ? 210.884 227.867 161.124 1.00 74.62  ? 711 PHE A CE2 1 
ATOM   5503  C  CZ  . PHE A 1 711 ? 209.677 227.796 160.478 1.00 75.48  ? 711 PHE A CZ  1 
ATOM   5504  N  N   . SER A 1 712 ? 213.258 221.385 160.820 1.00 70.13  ? 712 SER A N   1 
ATOM   5505  C  CA  . SER A 1 712 ? 214.131 220.306 160.382 1.00 71.62  ? 712 SER A CA  1 
ATOM   5506  C  C   . SER A 1 712 ? 213.323 219.184 159.752 1.00 73.62  ? 712 SER A C   1 
ATOM   5507  O  O   . SER A 1 712 ? 213.718 218.626 158.721 1.00 77.24  ? 712 SER A O   1 
ATOM   5508  C  CB  . SER A 1 712 ? 214.951 219.787 161.558 1.00 76.24  ? 712 SER A CB  1 
ATOM   5509  O  OG  . SER A 1 712 ? 215.596 220.852 162.230 1.00 82.41  ? 712 SER A OG  1 
ATOM   5510  N  N   . GLY A 1 713 ? 212.181 218.847 160.354 1.00 74.26  ? 713 GLY A N   1 
ATOM   5511  C  CA  . GLY A 1 713 ? 211.352 217.788 159.807 1.00 75.82  ? 713 GLY A CA  1 
ATOM   5512  C  C   . GLY A 1 713 ? 210.801 218.125 158.436 1.00 74.69  ? 713 GLY A C   1 
ATOM   5513  O  O   . GLY A 1 713 ? 210.828 217.295 157.523 1.00 74.44  ? 713 GLY A O   1 
ATOM   5514  N  N   . LEU A 1 714 ? 210.289 219.343 158.272 1.00 70.88  ? 714 LEU A N   1 
ATOM   5515  C  CA  . LEU A 1 714 ? 209.788 219.736 156.965 1.00 64.88  ? 714 LEU A CA  1 
ATOM   5516  C  C   . LEU A 1 714 ? 210.916 219.760 155.951 1.00 68.15  ? 714 LEU A C   1 
ATOM   5517  O  O   . LEU A 1 714 ? 210.717 219.437 154.775 1.00 71.35  ? 714 LEU A O   1 
ATOM   5518  C  CB  . LEU A 1 714 ? 209.103 221.091 157.046 1.00 62.57  ? 714 LEU A CB  1 
ATOM   5519  C  CG  . LEU A 1 714 ? 208.392 221.467 155.755 1.00 68.27  ? 714 LEU A CG  1 
ATOM   5520  C  CD1 . LEU A 1 714 ? 207.396 220.391 155.391 1.00 68.34  ? 714 LEU A CD1 1 
ATOM   5521  C  CD2 . LEU A 1 714 ? 207.696 222.803 155.902 1.00 70.97  ? 714 LEU A CD2 1 
ATOM   5522  N  N   . SER A 1 715 ? 212.118 220.121 156.399 1.00 70.83  ? 715 SER A N   1 
ATOM   5523  C  CA  . SER A 1 715 ? 213.263 220.138 155.503 1.00 73.21  ? 715 SER A CA  1 
ATOM   5524  C  C   . SER A 1 715 ? 213.598 218.739 155.020 1.00 70.04  ? 715 SER A C   1 
ATOM   5525  O  O   . SER A 1 715 ? 213.871 218.538 153.835 1.00 72.21  ? 715 SER A O   1 
ATOM   5526  C  CB  . SER A 1 715 ? 214.468 220.760 156.203 1.00 76.23  ? 715 SER A CB  1 
ATOM   5527  O  OG  . SER A 1 715 ? 214.867 219.972 157.309 1.00 77.38  ? 715 SER A OG  1 
ATOM   5528  N  N   . ARG A 1 716 ? 213.597 217.759 155.918 1.00 68.58  ? 716 ARG A N   1 
ATOM   5529  C  CA  . ARG A 1 716 ? 213.901 216.413 155.455 1.00 69.71  ? 716 ARG A CA  1 
ATOM   5530  C  C   . ARG A 1 716 ? 212.772 215.839 154.615 1.00 70.75  ? 716 ARG A C   1 
ATOM   5531  O  O   . ARG A 1 716 ? 213.032 215.027 153.722 1.00 72.37  ? 716 ARG A O   1 
ATOM   5532  C  CB  . ARG A 1 716 ? 214.211 215.467 156.618 1.00 69.58  ? 716 ARG A CB  1 
ATOM   5533  C  CG  . ARG A 1 716 ? 213.439 215.737 157.869 1.00 75.49  ? 716 ARG A CG  1 
ATOM   5534  C  CD  . ARG A 1 716 ? 213.618 214.646 158.908 1.00 81.80  ? 716 ARG A CD  1 
ATOM   5535  N  NE  . ARG A 1 716 ? 212.836 214.943 160.102 1.00 81.25  ? 716 ARG A NE  1 
ATOM   5536  C  CZ  . ARG A 1 716 ? 212.484 214.050 161.016 1.00 84.63  ? 716 ARG A CZ  1 
ATOM   5537  N  NH1 . ARG A 1 716 ? 212.839 212.781 160.917 1.00 91.03  ? 716 ARG A NH1 1 
ATOM   5538  N  NH2 . ARG A 1 716 ? 211.751 214.441 162.054 1.00 81.60  ? 716 ARG A NH2 1 
ATOM   5539  N  N   . LEU A 1 717 ? 211.530 216.247 154.869 1.00 69.25  ? 717 LEU A N   1 
ATOM   5540  C  CA  . LEU A 1 717 ? 210.433 215.763 154.045 1.00 69.78  ? 717 LEU A CA  1 
ATOM   5541  C  C   . LEU A 1 717 ? 210.476 216.350 152.640 1.00 69.88  ? 717 LEU A C   1 
ATOM   5542  O  O   . LEU A 1 717 ? 210.152 215.660 151.670 1.00 73.86  ? 717 LEU A O   1 
ATOM   5543  C  CB  . LEU A 1 717 ? 209.095 216.073 154.706 1.00 69.20  ? 717 LEU A CB  1 
ATOM   5544  C  CG  . LEU A 1 717 ? 208.743 215.207 155.915 1.00 67.76  ? 717 LEU A CG  1 
ATOM   5545  C  CD1 . LEU A 1 717 ? 207.241 215.138 156.087 1.00 68.28  ? 717 LEU A CD1 1 
ATOM   5546  C  CD2 . LEU A 1 717 ? 209.329 213.816 155.792 1.00 66.49  ? 717 LEU A CD2 1 
ATOM   5547  N  N   . VAL A 1 718 ? 210.879 217.609 152.500 1.00 67.91  ? 718 VAL A N   1 
ATOM   5548  C  CA  . VAL A 1 718 ? 210.884 218.223 151.179 1.00 67.02  ? 718 VAL A CA  1 
ATOM   5549  C  C   . VAL A 1 718 ? 212.224 218.100 150.466 1.00 70.78  ? 718 VAL A C   1 
ATOM   5550  O  O   . VAL A 1 718 ? 212.291 218.346 149.254 1.00 75.40  ? 718 VAL A O   1 
ATOM   5551  C  CB  . VAL A 1 718 ? 210.480 219.702 151.266 1.00 70.46  ? 718 VAL A CB  1 
ATOM   5552  C  CG1 . VAL A 1 718 ? 211.695 220.567 151.566 1.00 71.93  ? 718 VAL A CG1 1 
ATOM   5553  C  CG2 . VAL A 1 718 ? 209.797 220.140 149.983 1.00 69.82  ? 718 VAL A CG2 1 
ATOM   5554  N  N   . SER A 1 719 ? 213.292 217.726 151.172 1.00 72.88  ? 719 SER A N   1 
ATOM   5555  C  CA  . SER A 1 719 ? 214.599 217.617 150.532 1.00 76.89  ? 719 SER A CA  1 
ATOM   5556  C  C   . SER A 1 719 ? 214.670 216.372 149.665 1.00 72.66  ? 719 SER A C   1 
ATOM   5557  O  O   . SER A 1 719 ? 214.809 216.458 148.440 1.00 76.19  ? 719 SER A O   1 
ATOM   5558  C  CB  . SER A 1 719 ? 215.701 217.601 151.590 1.00 78.54  ? 719 SER A CB  1 
ATOM   5559  O  OG  . SER A 1 719 ? 215.346 216.762 152.672 1.00 80.88  ? 719 SER A OG  1 
ATOM   5560  N  N   . LEU A 1 720 ? 214.571 215.200 150.281 1.00 69.66  ? 720 LEU A N   1 
ATOM   5561  C  CA  . LEU A 1 720 ? 214.234 214.004 149.533 1.00 73.48  ? 720 LEU A CA  1 
ATOM   5562  C  C   . LEU A 1 720 ? 212.740 214.093 149.274 1.00 72.64  ? 720 LEU A C   1 
ATOM   5563  O  O   . LEU A 1 720 ? 211.963 214.187 150.234 1.00 78.46  ? 720 LEU A O   1 
ATOM   5564  C  CB  . LEU A 1 720 ? 214.592 212.743 150.311 1.00 82.40  ? 720 LEU A CB  1 
ATOM   5565  C  CG  . LEU A 1 720 ? 214.020 212.482 151.707 1.00 86.77  ? 720 LEU A CG  1 
ATOM   5566  C  CD1 . LEU A 1 720 ? 212.891 211.472 151.661 1.00 80.16  ? 720 LEU A CD1 1 
ATOM   5567  C  CD2 . LEU A 1 720 ? 215.111 212.012 152.646 1.00 88.82  ? 720 LEU A CD2 1 
ATOM   5568  N  N   . PRO A 1 721 ? 212.298 214.120 148.039 1.00 67.32  ? 721 PRO A N   1 
ATOM   5569  C  CA  . PRO A 1 721 ? 210.887 214.417 147.789 1.00 64.58  ? 721 PRO A CA  1 
ATOM   5570  C  C   . PRO A 1 721 ? 209.993 213.269 148.207 1.00 66.35  ? 721 PRO A C   1 
ATOM   5571  O  O   . PRO A 1 721 ? 209.933 212.245 147.521 1.00 71.68  ? 721 PRO A O   1 
ATOM   5572  C  CB  . PRO A 1 721 ? 210.831 214.648 146.272 1.00 65.57  ? 721 PRO A CB  1 
ATOM   5573  C  CG  . PRO A 1 721 ? 212.249 214.547 145.773 1.00 70.32  ? 721 PRO A CG  1 
ATOM   5574  C  CD  . PRO A 1 721 ? 213.036 213.822 146.806 1.00 69.16  ? 721 PRO A CD  1 
ATOM   5575  N  N   . VAL A 1 722 ? 209.297 213.417 149.326 1.00 59.06  ? 722 VAL A N   1 
ATOM   5576  C  CA  . VAL A 1 722 ? 208.304 212.429 149.715 1.00 54.03  ? 722 VAL A CA  1 
ATOM   5577  C  C   . VAL A 1 722 ? 207.108 212.602 148.792 1.00 53.40  ? 722 VAL A C   1 
ATOM   5578  O  O   . VAL A 1 722 ? 206.521 213.684 148.714 1.00 56.09  ? 722 VAL A O   1 
ATOM   5579  C  CB  . VAL A 1 722 ? 207.909 212.576 151.189 1.00 55.23  ? 722 VAL A CB  1 
ATOM   5580  C  CG1 . VAL A 1 722 ? 209.024 212.058 152.068 1.00 61.31  ? 722 VAL A CG1 1 
ATOM   5581  C  CG2 . VAL A 1 722 ? 207.582 214.009 151.528 1.00 63.68  ? 722 VAL A CG2 1 
ATOM   5582  N  N   . THR A 1 723 ? 206.768 211.545 148.062 1.00 52.09  ? 723 THR A N   1 
ATOM   5583  C  CA  . THR A 1 723 ? 205.776 211.680 147.007 1.00 54.27  ? 723 THR A CA  1 
ATOM   5584  C  C   . THR A 1 723 ? 204.410 212.032 147.569 1.00 51.41  ? 723 THR A C   1 
ATOM   5585  O  O   . THR A 1 723 ? 203.684 212.841 146.982 1.00 55.37  ? 723 THR A O   1 
ATOM   5586  C  CB  . THR A 1 723 ? 205.710 210.397 146.181 1.00 61.64  ? 723 THR A CB  1 
ATOM   5587  O  OG1 . THR A 1 723 ? 207.002 210.122 145.627 1.00 65.17  ? 723 THR A OG1 1 
ATOM   5588  C  CG2 . THR A 1 723 ? 204.706 210.538 145.049 1.00 60.47  ? 723 THR A CG2 1 
ATOM   5589  N  N   . GLU A 1 724 ? 204.035 211.452 148.702 1.00 46.91  ? 724 GLU A N   1 
ATOM   5590  C  CA  . GLU A 1 724 ? 202.671 211.633 149.162 1.00 45.57  ? 724 GLU A CA  1 
ATOM   5591  C  C   . GLU A 1 724 ? 202.580 211.398 150.658 1.00 39.48  ? 724 GLU A C   1 
ATOM   5592  O  O   . GLU A 1 724 ? 203.494 210.859 151.281 1.00 43.98  ? 724 GLU A O   1 
ATOM   5593  C  CB  . GLU A 1 724 ? 201.708 210.726 148.382 1.00 55.53  ? 724 GLU A CB  1 
ATOM   5594  C  CG  . GLU A 1 724 ? 201.188 209.462 149.058 1.00 54.71  ? 724 GLU A CG  1 
ATOM   5595  C  CD  . GLU A 1 724 ? 202.246 208.416 149.316 1.00 56.22  ? 724 GLU A CD  1 
ATOM   5596  O  OE1 . GLU A 1 724 ? 203.383 208.571 148.825 1.00 58.26  ? 724 GLU A OE1 1 
ATOM   5597  O  OE2 . GLU A 1 724 ? 201.919 207.413 149.980 1.00 53.91  ? 724 GLU A OE2 1 
ATOM   5598  N  N   . ILE A 1 725 ? 201.464 211.825 151.226 1.00 37.30  ? 725 ILE A N   1 
ATOM   5599  C  CA  . ILE A 1 725 ? 201.258 211.853 152.664 1.00 39.02  ? 725 ILE A CA  1 
ATOM   5600  C  C   . ILE A 1 725 ? 199.887 211.272 152.962 1.00 43.56  ? 725 ILE A C   1 
ATOM   5601  O  O   . ILE A 1 725 ? 198.938 211.478 152.199 1.00 48.39  ? 725 ILE A O   1 
ATOM   5602  C  CB  . ILE A 1 725 ? 201.390 213.291 153.201 1.00 38.67  ? 725 ILE A CB  1 
ATOM   5603  C  CG1 . ILE A 1 725 ? 201.067 213.361 154.682 1.00 40.42  ? 725 ILE A CG1 1 
ATOM   5604  C  CG2 . ILE A 1 725 ? 200.500 214.236 152.437 1.00 45.21  ? 725 ILE A CG2 1 
ATOM   5605  C  CD1 . ILE A 1 725 ? 201.514 214.639 155.302 1.00 50.27  ? 725 ILE A CD1 1 
ATOM   5606  N  N   . LYS A 1 726 ? 199.781 210.536 154.059 1.00 41.37  ? 726 LYS A N   1 
ATOM   5607  C  CA  . LYS A 1 726 ? 198.550 209.852 154.402 1.00 37.75  ? 726 LYS A CA  1 
ATOM   5608  C  C   . LYS A 1 726 ? 198.012 210.360 155.726 1.00 37.18  ? 726 LYS A C   1 
ATOM   5609  O  O   . LYS A 1 726 ? 198.771 210.721 156.626 1.00 45.06  ? 726 LYS A O   1 
ATOM   5610  C  CB  . LYS A 1 726 ? 198.781 208.345 154.475 1.00 43.53  ? 726 LYS A CB  1 
ATOM   5611  C  CG  . LYS A 1 726 ? 197.606 207.502 154.014 1.00 55.73  ? 726 LYS A CG  1 
ATOM   5612  C  CD  . LYS A 1 726 ? 197.798 206.042 154.393 1.00 57.77  ? 726 LYS A CD  1 
ATOM   5613  C  CE  . LYS A 1 726 ? 198.321 205.238 153.212 1.00 56.27  ? 726 LYS A CE  1 
ATOM   5614  N  NZ  . LYS A 1 726 ? 198.451 203.795 153.536 1.00 62.31  ? 726 LYS A NZ  1 
ATOM   5615  N  N   . ILE A 1 727 ? 196.695 210.381 155.837 1.00 35.85  ? 727 ILE A N   1 
ATOM   5616  C  CA  . ILE A 1 727 ? 196.015 210.661 157.090 1.00 41.87  ? 727 ILE A CA  1 
ATOM   5617  C  C   . ILE A 1 727 ? 195.616 209.326 157.691 1.00 52.54  ? 727 ILE A C   1 
ATOM   5618  O  O   . ILE A 1 727 ? 194.974 208.507 157.025 1.00 57.18  ? 727 ILE A O   1 
ATOM   5619  C  CB  . ILE A 1 727 ? 194.792 211.563 156.883 1.00 45.06  ? 727 ILE A CB  1 
ATOM   5620  C  CG1 . ILE A 1 727 ? 195.095 212.648 155.857 1.00 46.30  ? 727 ILE A CG1 1 
ATOM   5621  C  CG2 . ILE A 1 727 ? 194.389 212.210 158.177 1.00 51.38  ? 727 ILE A CG2 1 
ATOM   5622  C  CD1 . ILE A 1 727 ? 193.928 213.560 155.595 1.00 50.40  ? 727 ILE A CD1 1 
ATOM   5623  N  N   . ASP A 1 728 ? 195.999 209.104 158.941 1.00 54.41  ? 728 ASP A N   1 
ATOM   5624  C  CA  . ASP A 1 728 ? 195.677 207.851 159.606 1.00 60.71  ? 728 ASP A CA  1 
ATOM   5625  C  C   . ASP A 1 728 ? 194.167 207.723 159.748 1.00 60.66  ? 728 ASP A C   1 
ATOM   5626  O  O   . ASP A 1 728 ? 193.438 208.715 159.776 1.00 62.47  ? 728 ASP A O   1 
ATOM   5627  C  CB  . ASP A 1 728 ? 196.378 207.795 160.972 1.00 64.41  ? 728 ASP A CB  1 
ATOM   5628  C  CG  . ASP A 1 728 ? 195.991 206.575 161.815 1.00 71.47  ? 728 ASP A CG  1 
ATOM   5629  O  OD1 . ASP A 1 728 ? 194.792 206.252 161.955 1.00 70.60  ? 728 ASP A OD1 1 
ATOM   5630  O  OD2 . ASP A 1 728 ? 196.914 205.928 162.351 1.00 74.95  ? 728 ASP A OD2 1 
ATOM   5631  N  N   . LYS A 1 729 ? 193.697 206.478 159.816 1.00 60.42  ? 729 LYS A N   1 
ATOM   5632  C  CA  . LYS A 1 729 ? 192.272 206.232 159.987 1.00 61.02  ? 729 LYS A CA  1 
ATOM   5633  C  C   . LYS A 1 729 ? 191.736 206.849 161.267 1.00 64.52  ? 729 LYS A C   1 
ATOM   5634  O  O   . LYS A 1 729 ? 190.534 207.119 161.354 1.00 71.04  ? 729 LYS A O   1 
ATOM   5635  C  CB  . LYS A 1 729 ? 191.992 204.732 159.987 1.00 65.34  ? 729 LYS A CB  1 
ATOM   5636  C  CG  . LYS A 1 729 ? 190.528 204.376 159.825 1.00 66.09  ? 729 LYS A CG  1 
ATOM   5637  C  CD  . LYS A 1 729 ? 190.317 202.875 159.856 1.00 69.94  ? 729 LYS A CD  1 
ATOM   5638  C  CE  . LYS A 1 729 ? 190.351 202.350 161.282 1.00 75.36  ? 729 LYS A CE  1 
ATOM   5639  N  NZ  . LYS A 1 729 ? 189.112 202.707 162.027 1.00 77.07  ? 729 LYS A NZ  1 
ATOM   5640  N  N   . SER A 1 730 ? 192.596 207.082 162.259 1.00 59.49  ? 730 SER A N   1 
ATOM   5641  C  CA  . SER A 1 730 ? 192.134 207.686 163.502 1.00 60.20  ? 730 SER A CA  1 
ATOM   5642  C  C   . SER A 1 730 ? 191.584 209.082 163.263 1.00 63.53  ? 730 SER A C   1 
ATOM   5643  O  O   . SER A 1 730 ? 190.540 209.450 163.810 1.00 68.95  ? 730 SER A O   1 
ATOM   5644  C  CB  . SER A 1 730 ? 193.276 207.735 164.507 1.00 63.91  ? 730 SER A CB  1 
ATOM   5645  O  OG  . SER A 1 730 ? 194.316 208.562 164.025 1.00 65.00  ? 730 SER A OG  1 
ATOM   5646  N  N   . PHE A 1 731 ? 192.271 209.871 162.443 1.00 62.59  ? 731 PHE A N   1 
ATOM   5647  C  CA  . PHE A 1 731 ? 191.829 211.235 162.183 1.00 66.06  ? 731 PHE A CA  1 
ATOM   5648  C  C   . PHE A 1 731 ? 190.493 211.251 161.454 1.00 69.19  ? 731 PHE A C   1 
ATOM   5649  O  O   . PHE A 1 731 ? 189.566 211.968 161.847 1.00 74.80  ? 731 PHE A O   1 
ATOM   5650  C  CB  . PHE A 1 731 ? 192.888 211.977 161.367 1.00 61.64  ? 731 PHE A CB  1 
ATOM   5651  C  CG  . PHE A 1 731 ? 194.128 212.317 162.137 1.00 58.07  ? 731 PHE A CG  1 
ATOM   5652  C  CD1 . PHE A 1 731 ? 195.046 211.340 162.469 1.00 60.12  ? 731 PHE A CD1 1 
ATOM   5653  C  CD2 . PHE A 1 731 ? 194.385 213.614 162.510 1.00 59.11  ? 731 PHE A CD2 1 
ATOM   5654  C  CE1 . PHE A 1 731 ? 196.184 211.653 163.173 1.00 58.85  ? 731 PHE A CE1 1 
ATOM   5655  C  CE2 . PHE A 1 731 ? 195.523 213.929 163.214 1.00 57.88  ? 731 PHE A CE2 1 
ATOM   5656  C  CZ  . PHE A 1 731 ? 196.422 212.948 163.544 1.00 55.30  ? 731 PHE A CZ  1 
ATOM   5657  N  N   . VAL A 1 732 ? 190.372 210.454 160.393 1.00 64.01  ? 732 VAL A N   1 
ATOM   5658  C  CA  . VAL A 1 732 ? 189.227 210.588 159.503 1.00 62.77  ? 732 VAL A CA  1 
ATOM   5659  C  C   . VAL A 1 732 ? 188.003 209.928 160.109 1.00 68.67  ? 732 VAL A C   1 
ATOM   5660  O  O   . VAL A 1 732 ? 186.870 210.218 159.712 1.00 74.37  ? 732 VAL A O   1 
ATOM   5661  C  CB  . VAL A 1 732 ? 189.574 210.012 158.122 1.00 58.19  ? 732 VAL A CB  1 
ATOM   5662  C  CG1 . VAL A 1 732 ? 188.548 210.416 157.101 1.00 61.83  ? 732 VAL A CG1 1 
ATOM   5663  C  CG2 . VAL A 1 732 ? 190.938 210.480 157.697 1.00 57.95  ? 732 VAL A CG2 1 
ATOM   5664  N  N   . ASP A 1 733 ? 188.198 209.036 161.076 1.00 71.18  ? 733 ASP A N   1 
ATOM   5665  C  CA  . ASP A 1 733 ? 187.061 208.456 161.770 1.00 77.02  ? 733 ASP A CA  1 
ATOM   5666  C  C   . ASP A 1 733 ? 186.356 209.475 162.649 1.00 77.80  ? 733 ASP A C   1 
ATOM   5667  O  O   . ASP A 1 733 ? 185.210 209.246 163.046 1.00 84.20  ? 733 ASP A O   1 
ATOM   5668  C  CB  . ASP A 1 733 ? 187.511 207.261 162.612 1.00 77.56  ? 733 ASP A CB  1 
ATOM   5669  C  CG  . ASP A 1 733 ? 187.650 205.991 161.795 1.00 75.10  ? 733 ASP A CG  1 
ATOM   5670  O  OD1 . ASP A 1 733 ? 187.208 205.983 160.626 1.00 72.03  ? 733 ASP A OD1 1 
ATOM   5671  O  OD2 . ASP A 1 733 ? 188.203 205.001 162.319 1.00 71.87  ? 733 ASP A OD2 1 
ATOM   5672  N  N   . ARG A 1 734 ? 187.014 210.589 162.963 1.00 74.64  ? 734 ARG A N   1 
ATOM   5673  C  CA  . ARG A 1 734 ? 186.439 211.630 163.801 1.00 81.58  ? 734 ARG A CA  1 
ATOM   5674  C  C   . ARG A 1 734 ? 186.387 212.978 163.100 1.00 86.99  ? 734 ARG A C   1 
ATOM   5675  O  O   . ARG A 1 734 ? 186.211 214.005 163.763 1.00 90.44  ? 734 ARG A O   1 
ATOM   5676  C  CB  . ARG A 1 734 ? 187.217 211.743 165.114 1.00 82.27  ? 734 ARG A CB  1 
ATOM   5677  C  CG  . ARG A 1 734 ? 187.937 210.467 165.516 1.00 80.30  ? 734 ARG A CG  1 
ATOM   5678  C  CD  . ARG A 1 734 ? 189.040 210.723 166.531 1.00 83.39  ? 734 ARG A CD  1 
ATOM   5679  N  NE  . ARG A 1 734 ? 189.957 211.779 166.119 1.00 88.07  ? 734 ARG A NE  1 
ATOM   5680  C  CZ  . ARG A 1 734 ? 190.924 212.266 166.883 1.00 87.68  ? 734 ARG A CZ  1 
ATOM   5681  N  NH1 . ARG A 1 734 ? 191.122 211.823 168.114 1.00 84.04  ? 734 ARG A NH1 1 
ATOM   5682  N  NH2 . ARG A 1 734 ? 191.713 213.222 166.401 1.00 85.29  ? 734 ARG A NH2 1 
ATOM   5683  N  N   . CYS A 1 735 ? 186.535 213.001 161.775 1.00 84.71  ? 735 CYS A N   1 
ATOM   5684  C  CA  . CYS A 1 735 ? 186.498 214.265 161.051 1.00 88.00  ? 735 CYS A CA  1 
ATOM   5685  C  C   . CYS A 1 735 ? 185.131 214.926 161.155 1.00 90.88  ? 735 CYS A C   1 
ATOM   5686  O  O   . CYS A 1 735 ? 185.034 216.145 161.332 1.00 87.52  ? 735 CYS A O   1 
ATOM   5687  C  CB  . CYS A 1 735 ? 186.872 214.033 159.590 1.00 86.36  ? 735 CYS A CB  1 
ATOM   5688  S  SG  . CYS A 1 735 ? 185.754 212.908 158.733 1.00 91.12  ? 735 CYS A SG  1 
ATOM   5689  N  N   . LEU A 1 736 ? 184.062 214.137 161.048 1.00 94.65  ? 736 LEU A N   1 
ATOM   5690  C  CA  . LEU A 1 736 ? 182.714 214.691 161.082 1.00 96.36  ? 736 LEU A CA  1 
ATOM   5691  C  C   . LEU A 1 736 ? 182.370 215.306 162.430 1.00 96.50  ? 736 LEU A C   1 
ATOM   5692  O  O   . LEU A 1 736 ? 181.692 216.338 162.473 1.00 96.49  ? 736 LEU A O   1 
ATOM   5693  C  CB  . LEU A 1 736 ? 181.696 213.604 160.738 1.00 95.75  ? 736 LEU A CB  1 
ATOM   5694  C  CG  . LEU A 1 736 ? 181.892 212.893 159.399 1.00 92.88  ? 736 LEU A CG  1 
ATOM   5695  C  CD1 . LEU A 1 736 ? 180.934 211.719 159.271 1.00 86.48  ? 736 LEU A CD1 1 
ATOM   5696  C  CD2 . LEU A 1 736 ? 181.704 213.867 158.249 1.00 90.30  ? 736 LEU A CD2 1 
ATOM   5697  N  N   . THR A 1 737 ? 182.818 214.703 163.528 1.00 95.11  ? 737 THR A N   1 
ATOM   5698  C  CA  . THR A 1 737 ? 182.461 215.165 164.862 1.00 95.31  ? 737 THR A CA  1 
ATOM   5699  C  C   . THR A 1 737 ? 183.213 216.411 165.300 1.00 99.97  ? 737 THR A C   1 
ATOM   5700  O  O   . THR A 1 737 ? 182.614 217.288 165.930 1.00 103.06 ? 737 THR A O   1 
ATOM   5701  C  CB  . THR A 1 737 ? 182.714 214.060 165.889 1.00 96.19  ? 737 THR A CB  1 
ATOM   5702  O  OG1 . THR A 1 737 ? 184.091 214.082 166.280 1.00 99.19  ? 737 THR A OG1 1 
ATOM   5703  C  CG2 . THR A 1 737 ? 182.379 212.699 165.300 1.00 95.51  ? 737 THR A CG2 1 
ATOM   5704  N  N   . GLU A 1 738 ? 184.499 216.520 164.984 1.00 99.12  ? 738 GLU A N   1 
ATOM   5705  C  CA  . GLU A 1 738 ? 185.335 217.610 165.467 1.00 100.01 ? 738 GLU A CA  1 
ATOM   5706  C  C   . GLU A 1 738 ? 185.700 218.553 164.329 1.00 99.38  ? 738 GLU A C   1 
ATOM   5707  O  O   . GLU A 1 738 ? 185.840 218.129 163.176 1.00 97.21  ? 738 GLU A O   1 
ATOM   5708  C  CB  . GLU A 1 738 ? 186.610 217.077 166.121 1.00 98.49  ? 738 GLU A CB  1 
ATOM   5709  C  CG  . GLU A 1 738 ? 187.188 218.003 167.171 1.00 99.53  ? 738 GLU A CG  1 
ATOM   5710  C  CD  . GLU A 1 738 ? 186.360 218.035 168.436 1.00 106.64 ? 738 GLU A CD  1 
ATOM   5711  O  OE1 . GLU A 1 738 ? 185.612 217.065 168.683 1.00 105.82 ? 738 GLU A OE1 1 
ATOM   5712  O  OE2 . GLU A 1 738 ? 186.455 219.029 169.185 1.00 110.91 ? 738 GLU A OE2 1 
ATOM   5713  N  N   . LYS A 1 739 ? 185.852 219.835 164.664 1.00 97.44  ? 739 LYS A N   1 
ATOM   5714  C  CA  . LYS A 1 739 ? 186.190 220.861 163.685 1.00 97.24  ? 739 LYS A CA  1 
ATOM   5715  C  C   . LYS A 1 739 ? 187.690 221.070 163.538 1.00 91.53  ? 739 LYS A C   1 
ATOM   5716  O  O   . LYS A 1 739 ? 188.166 221.342 162.428 1.00 89.64  ? 739 LYS A O   1 
ATOM   5717  C  CB  . LYS A 1 739 ? 185.530 222.188 164.069 1.00 98.91  ? 739 LYS A CB  1 
ATOM   5718  C  CG  . LYS A 1 739 ? 185.703 223.298 163.044 1.00 96.00  ? 739 LYS A CG  1 
ATOM   5719  C  CD  . LYS A 1 739 ? 185.067 222.927 161.715 1.00 96.97  ? 739 LYS A CD  1 
ATOM   5720  C  CE  . LYS A 1 739 ? 185.000 224.124 160.780 1.00 95.77  ? 739 LYS A CE  1 
ATOM   5721  N  NZ  . LYS A 1 739 ? 186.356 224.558 160.342 1.00 96.66  ? 739 LYS A NZ  1 
ATOM   5722  N  N   . ARG A 1 740 ? 188.453 220.957 164.626 1.00 88.36  ? 740 ARG A N   1 
ATOM   5723  C  CA  . ARG A 1 740 ? 189.882 221.220 164.517 1.00 91.33  ? 740 ARG A CA  1 
ATOM   5724  C  C   . ARG A 1 740 ? 190.578 220.107 163.749 1.00 89.68  ? 740 ARG A C   1 
ATOM   5725  O  O   . ARG A 1 740 ? 191.621 220.341 163.129 1.00 91.01  ? 740 ARG A O   1 
ATOM   5726  C  CB  . ARG A 1 740 ? 190.466 221.480 165.917 1.00 92.62  ? 740 ARG A CB  1 
ATOM   5727  C  CG  . ARG A 1 740 ? 190.623 220.343 166.955 1.00 95.08  ? 740 ARG A CG  1 
ATOM   5728  C  CD  . ARG A 1 740 ? 191.507 219.163 166.571 1.00 96.59  ? 740 ARG A CD  1 
ATOM   5729  N  NE  . ARG A 1 740 ? 191.362 218.059 167.513 1.00 101.79 ? 740 ARG A NE  1 
ATOM   5730  C  CZ  . ARG A 1 740 ? 191.731 216.809 167.274 1.00 102.21 ? 740 ARG A CZ  1 
ATOM   5731  N  NH1 . ARG A 1 740 ? 192.384 216.480 166.173 1.00 99.27  ? 740 ARG A NH1 1 
ATOM   5732  N  NH2 . ARG A 1 740 ? 191.466 215.870 168.178 1.00 102.45 ? 740 ARG A NH2 1 
ATOM   5733  N  N   . ILE A 1 741 ? 189.987 218.912 163.730 1.00 86.08  ? 741 ILE A N   1 
ATOM   5734  C  CA  . ILE A 1 741 ? 190.423 217.897 162.781 1.00 85.65  ? 741 ILE A CA  1 
ATOM   5735  C  C   . ILE A 1 741 ? 190.256 218.417 161.366 1.00 84.09  ? 741 ILE A C   1 
ATOM   5736  O  O   . ILE A 1 741 ? 191.129 218.231 160.514 1.00 85.68  ? 741 ILE A O   1 
ATOM   5737  C  CB  . ILE A 1 741 ? 189.636 216.592 162.985 1.00 92.38  ? 741 ILE A CB  1 
ATOM   5738  C  CG1 . ILE A 1 741 ? 189.924 215.996 164.357 1.00 95.52  ? 741 ILE A CG1 1 
ATOM   5739  C  CG2 . ILE A 1 741 ? 189.968 215.591 161.887 1.00 84.49  ? 741 ILE A CG2 1 
ATOM   5740  C  CD1 . ILE A 1 741 ? 189.297 214.645 164.573 1.00 89.54  ? 741 ILE A CD1 1 
ATOM   5741  N  N   . LEU A 1 742 ? 189.126 219.070 161.092 1.00 86.84  ? 742 LEU A N   1 
ATOM   5742  C  CA  . LEU A 1 742 ? 188.901 219.613 159.759 1.00 89.46  ? 742 LEU A CA  1 
ATOM   5743  C  C   . LEU A 1 742 ? 189.936 220.674 159.421 1.00 86.55  ? 742 LEU A C   1 
ATOM   5744  O  O   . LEU A 1 742 ? 190.458 220.706 158.303 1.00 85.36  ? 742 LEU A O   1 
ATOM   5745  C  CB  . LEU A 1 742 ? 187.488 220.186 159.651 1.00 91.12  ? 742 LEU A CB  1 
ATOM   5746  C  CG  . LEU A 1 742 ? 186.334 219.202 159.841 1.00 93.39  ? 742 LEU A CG  1 
ATOM   5747  C  CD1 . LEU A 1 742 ? 185.009 219.858 159.492 1.00 93.23  ? 742 LEU A CD1 1 
ATOM   5748  C  CD2 . LEU A 1 742 ? 186.554 217.953 159.003 1.00 90.62  ? 742 LEU A CD2 1 
ATOM   5749  N  N   . ALA A 1 743 ? 190.243 221.551 160.378 1.00 85.11  ? 743 ALA A N   1 
ATOM   5750  C  CA  . ALA A 1 743 ? 191.252 222.577 160.140 1.00 84.67  ? 743 ALA A CA  1 
ATOM   5751  C  C   . ALA A 1 743 ? 192.607 221.951 159.853 1.00 79.92  ? 743 ALA A C   1 
ATOM   5752  O  O   . ALA A 1 743 ? 193.316 222.375 158.931 1.00 80.16  ? 743 ALA A O   1 
ATOM   5753  C  CB  . ALA A 1 743 ? 191.337 223.519 161.339 1.00 88.69  ? 743 ALA A CB  1 
ATOM   5754  N  N   . LEU A 1 744 ? 192.979 220.933 160.628 1.00 75.38  ? 744 LEU A N   1 
ATOM   5755  C  CA  . LEU A 1 744 ? 194.218 220.222 160.357 1.00 73.62  ? 744 LEU A CA  1 
ATOM   5756  C  C   . LEU A 1 744 ? 194.191 219.618 158.964 1.00 75.04  ? 744 LEU A C   1 
ATOM   5757  O  O   . LEU A 1 744 ? 195.193 219.655 158.246 1.00 72.85  ? 744 LEU A O   1 
ATOM   5758  C  CB  . LEU A 1 744 ? 194.437 219.141 161.410 1.00 73.25  ? 744 LEU A CB  1 
ATOM   5759  C  CG  . LEU A 1 744 ? 195.775 218.407 161.438 1.00 71.46  ? 744 LEU A CG  1 
ATOM   5760  C  CD1 . LEU A 1 744 ? 196.912 219.295 160.960 1.00 73.15  ? 744 LEU A CD1 1 
ATOM   5761  C  CD2 . LEU A 1 744 ? 196.048 217.899 162.839 1.00 67.95  ? 744 LEU A CD2 1 
ATOM   5762  N  N   . LEU A 1 745 ? 193.044 219.075 158.560 1.00 80.15  ? 745 LEU A N   1 
ATOM   5763  C  CA  . LEU A 1 745 ? 192.934 218.457 157.244 1.00 77.39  ? 745 LEU A CA  1 
ATOM   5764  C  C   . LEU A 1 745 ? 193.127 219.484 156.136 1.00 73.41  ? 745 LEU A C   1 
ATOM   5765  O  O   . LEU A 1 745 ? 193.826 219.221 155.152 1.00 68.43  ? 745 LEU A O   1 
ATOM   5766  C  CB  . LEU A 1 745 ? 191.579 217.764 157.103 1.00 79.79  ? 745 LEU A CB  1 
ATOM   5767  C  CG  . LEU A 1 745 ? 191.560 216.238 157.195 1.00 77.58  ? 745 LEU A CG  1 
ATOM   5768  C  CD1 . LEU A 1 745 ? 192.067 215.769 158.544 1.00 74.01  ? 745 LEU A CD1 1 
ATOM   5769  C  CD2 . LEU A 1 745 ? 190.162 215.703 156.930 1.00 79.15  ? 745 LEU A CD2 1 
ATOM   5770  N  N   . GLU A 1 746 ? 192.500 220.659 156.266 1.00 76.03  ? 746 GLU A N   1 
ATOM   5771  C  CA  . GLU A 1 746 ? 192.688 221.672 155.231 1.00 74.42  ? 746 GLU A CA  1 
ATOM   5772  C  C   . GLU A 1 746 ? 194.125 222.158 155.205 1.00 67.68  ? 746 GLU A C   1 
ATOM   5773  O  O   . GLU A 1 746 ? 194.672 222.424 154.133 1.00 67.26  ? 746 GLU A O   1 
ATOM   5774  C  CB  . GLU A 1 746 ? 191.738 222.867 155.378 1.00 80.44  ? 746 GLU A CB  1 
ATOM   5775  C  CG  . GLU A 1 746 ? 190.267 222.587 155.095 1.00 86.02  ? 746 GLU A CG  1 
ATOM   5776  C  CD  . GLU A 1 746 ? 189.410 222.585 156.335 1.00 91.20  ? 746 GLU A CD  1 
ATOM   5777  O  OE1 . GLU A 1 746 ? 189.915 223.002 157.393 1.00 89.01  ? 746 GLU A OE1 1 
ATOM   5778  O  OE2 . GLU A 1 746 ? 188.237 222.165 156.254 1.00 92.44  ? 746 GLU A OE2 1 
ATOM   5779  N  N   . ALA A 1 747 ? 194.757 222.276 156.372 1.00 66.85  ? 747 ALA A N   1 
ATOM   5780  C  CA  . ALA A 1 747 ? 196.162 222.659 156.400 1.00 67.37  ? 747 ALA A CA  1 
ATOM   5781  C  C   . ALA A 1 747 ? 197.020 221.628 155.681 1.00 67.44  ? 747 ALA A C   1 
ATOM   5782  O  O   . ALA A 1 747 ? 197.901 221.978 154.887 1.00 66.79  ? 747 ALA A O   1 
ATOM   5783  C  CB  . ALA A 1 747 ? 196.629 222.837 157.843 1.00 69.65  ? 747 ALA A CB  1 
ATOM   5784  N  N   . ILE A 1 748 ? 196.764 220.347 155.942 1.00 66.50  ? 748 ILE A N   1 
ATOM   5785  C  CA  . ILE A 1 748 ? 197.541 219.282 155.320 1.00 64.59  ? 748 ILE A CA  1 
ATOM   5786  C  C   . ILE A 1 748 ? 197.318 219.267 153.817 1.00 63.61  ? 748 ILE A C   1 
ATOM   5787  O  O   . ILE A 1 748 ? 198.264 219.115 153.039 1.00 68.58  ? 748 ILE A O   1 
ATOM   5788  C  CB  . ILE A 1 748 ? 197.196 217.928 155.957 1.00 64.54  ? 748 ILE A CB  1 
ATOM   5789  C  CG1 . ILE A 1 748 ? 197.510 217.947 157.448 1.00 66.28  ? 748 ILE A CG1 1 
ATOM   5790  C  CG2 . ILE A 1 748 ? 197.981 216.817 155.286 1.00 61.16  ? 748 ILE A CG2 1 
ATOM   5791  C  CD1 . ILE A 1 748 ? 197.125 216.687 158.165 1.00 65.62  ? 748 ILE A CD1 1 
ATOM   5792  N  N   . THR A 1 749 ? 196.072 219.428 153.383 1.00 60.59  ? 749 THR A N   1 
ATOM   5793  C  CA  . THR A 1 749 ? 195.791 219.444 151.955 1.00 62.86  ? 749 THR A CA  1 
ATOM   5794  C  C   . THR A 1 749 ? 196.428 220.650 151.279 1.00 67.53  ? 749 THR A C   1 
ATOM   5795  O  O   . THR A 1 749 ? 196.942 220.541 150.160 1.00 65.72  ? 749 THR A O   1 
ATOM   5796  C  CB  . THR A 1 749 ? 194.287 219.433 151.724 1.00 67.10  ? 749 THR A CB  1 
ATOM   5797  O  OG1 . THR A 1 749 ? 193.669 220.370 152.606 1.00 71.69  ? 749 THR A OG1 1 
ATOM   5798  C  CG2 . THR A 1 749 ? 193.727 218.053 152.001 1.00 68.34  ? 749 THR A CG2 1 
ATOM   5799  N  N   . SER A 1 750 ? 196.394 221.813 151.934 1.00 69.29  ? 750 SER A N   1 
ATOM   5800  C  CA  . SER A 1 750 ? 197.015 223.000 151.362 1.00 66.70  ? 750 SER A CA  1 
ATOM   5801  C  C   . SER A 1 750 ? 198.519 222.827 151.253 1.00 64.10  ? 750 SER A C   1 
ATOM   5802  O  O   . SER A 1 750 ? 199.120 223.194 150.239 1.00 66.52  ? 750 SER A O   1 
ATOM   5803  C  CB  . SER A 1 750 ? 196.678 224.226 152.205 1.00 64.98  ? 750 SER A CB  1 
ATOM   5804  O  OG  . SER A 1 750 ? 197.084 224.040 153.548 1.00 63.85  ? 750 SER A OG  1 
ATOM   5805  N  N   . ILE A 1 751 ? 199.145 222.268 152.287 1.00 60.05  ? 751 ILE A N   1 
ATOM   5806  C  CA  . ILE A 1 751 ? 200.577 222.003 152.222 1.00 58.66  ? 751 ILE A CA  1 
ATOM   5807  C  C   . ILE A 1 751 ? 200.878 221.022 151.104 1.00 58.63  ? 751 ILE A C   1 
ATOM   5808  O  O   . ILE A 1 751 ? 201.865 221.169 150.374 1.00 59.72  ? 751 ILE A O   1 
ATOM   5809  C  CB  . ILE A 1 751 ? 201.085 221.493 153.579 1.00 58.34  ? 751 ILE A CB  1 
ATOM   5810  C  CG1 . ILE A 1 751 ? 201.112 222.642 154.579 1.00 63.80  ? 751 ILE A CG1 1 
ATOM   5811  C  CG2 . ILE A 1 751 ? 202.461 220.900 153.441 1.00 57.57  ? 751 ILE A CG2 1 
ATOM   5812  C  CD1 . ILE A 1 751 ? 201.054 222.199 156.001 1.00 67.91  ? 751 ILE A CD1 1 
ATOM   5813  N  N   . GLY A 1 752 ? 200.025 220.012 150.945 1.00 62.76  ? 752 GLY A N   1 
ATOM   5814  C  CA  . GLY A 1 752 ? 200.234 219.044 149.885 1.00 66.57  ? 752 GLY A CA  1 
ATOM   5815  C  C   . GLY A 1 752 ? 200.133 219.662 148.507 1.00 68.18  ? 752 GLY A C   1 
ATOM   5816  O  O   . GLY A 1 752 ? 200.936 219.362 147.621 1.00 71.14  ? 752 GLY A O   1 
ATOM   5817  N  N   . GLN A 1 753 ? 199.145 220.531 148.307 1.00 65.54  ? 753 GLN A N   1 
ATOM   5818  C  CA  . GLN A 1 753 ? 199.047 221.240 147.039 1.00 66.05  ? 753 GLN A CA  1 
ATOM   5819  C  C   . GLN A 1 753 ? 200.267 222.123 146.818 1.00 65.75  ? 753 GLN A C   1 
ATOM   5820  O  O   . GLN A 1 753 ? 200.807 222.187 145.708 1.00 66.37  ? 753 GLN A O   1 
ATOM   5821  C  CB  . GLN A 1 753 ? 197.768 222.074 146.998 1.00 65.50  ? 753 GLN A CB  1 
ATOM   5822  C  CG  . GLN A 1 753 ? 196.553 221.328 146.492 1.00 70.75  ? 753 GLN A CG  1 
ATOM   5823  C  CD  . GLN A 1 753 ? 195.253 221.903 147.024 1.00 79.37  ? 753 GLN A CD  1 
ATOM   5824  O  OE1 . GLN A 1 753 ? 195.255 222.740 147.926 1.00 79.48  ? 753 GLN A OE1 1 
ATOM   5825  N  NE2 . GLN A 1 753 ? 194.134 221.460 146.462 1.00 80.44  ? 753 GLN A NE2 1 
ATOM   5826  N  N   . SER A 1 754 ? 200.723 222.799 147.874 1.00 63.98  ? 754 SER A N   1 
ATOM   5827  C  CA  . SER A 1 754 ? 201.842 223.724 147.747 1.00 64.12  ? 754 SER A CA  1 
ATOM   5828  C  C   . SER A 1 754 ? 203.127 223.002 147.369 1.00 65.36  ? 754 SER A C   1 
ATOM   5829  O  O   . SER A 1 754 ? 203.881 223.473 146.510 1.00 71.43  ? 754 SER A O   1 
ATOM   5830  C  CB  . SER A 1 754 ? 202.027 224.483 149.056 1.00 62.18  ? 754 SER A CB  1 
ATOM   5831  O  OG  . SER A 1 754 ? 202.475 223.605 150.071 1.00 64.48  ? 754 SER A OG  1 
ATOM   5832  N  N   . LEU A 1 755 ? 203.395 221.859 147.991 1.00 60.06  ? 755 LEU A N   1 
ATOM   5833  C  CA  . LEU A 1 755 ? 204.655 221.155 147.802 1.00 60.89  ? 755 LEU A CA  1 
ATOM   5834  C  C   . LEU A 1 755 ? 204.553 220.000 146.814 1.00 64.89  ? 755 LEU A C   1 
ATOM   5835  O  O   . LEU A 1 755 ? 205.499 219.213 146.708 1.00 67.54  ? 755 LEU A O   1 
ATOM   5836  C  CB  . LEU A 1 755 ? 205.168 220.633 149.141 1.00 58.32  ? 755 LEU A CB  1 
ATOM   5837  C  CG  . LEU A 1 755 ? 205.180 221.595 150.320 1.00 61.89  ? 755 LEU A CG  1 
ATOM   5838  C  CD1 . LEU A 1 755 ? 205.798 220.922 151.523 1.00 62.67  ? 755 LEU A CD1 1 
ATOM   5839  C  CD2 . LEU A 1 755 ? 205.936 222.859 149.964 1.00 64.45  ? 755 LEU A CD2 1 
ATOM   5840  N  N   . ASN A 1 756 ? 203.439 219.885 146.088 1.00 65.08  ? 756 ASN A N   1 
ATOM   5841  C  CA  . ASN A 1 756 ? 203.182 218.752 145.196 1.00 63.33  ? 756 ASN A CA  1 
ATOM   5842  C  C   . ASN A 1 756 ? 203.160 217.429 145.965 1.00 63.58  ? 756 ASN A C   1 
ATOM   5843  O  O   . ASN A 1 756 ? 203.775 216.439 145.565 1.00 62.09  ? 756 ASN A O   1 
ATOM   5844  C  CB  . ASN A 1 756 ? 204.202 218.699 144.057 1.00 61.29  ? 756 ASN A CB  1 
ATOM   5845  C  CG  . ASN A 1 756 ? 204.536 220.065 143.518 1.00 72.09  ? 756 ASN A CG  1 
ATOM   5846  O  OD1 . ASN A 1 756 ? 203.716 220.703 142.859 1.00 78.73  ? 756 ASN A OD1 1 
ATOM   5847  N  ND2 . ASN A 1 756 ? 205.746 220.531 143.800 1.00 75.69  ? 756 ASN A ND2 1 
ATOM   5848  N  N   . LEU A 1 757 ? 202.441 217.418 147.082 1.00 61.25  ? 757 LEU A N   1 
ATOM   5849  C  CA  . LEU A 1 757 ? 202.270 216.220 147.890 1.00 54.51  ? 757 LEU A CA  1 
ATOM   5850  C  C   . LEU A 1 757 ? 200.854 215.691 147.722 1.00 57.27  ? 757 LEU A C   1 
ATOM   5851  O  O   . LEU A 1 757 ? 199.889 216.459 147.766 1.00 59.29  ? 757 LEU A O   1 
ATOM   5852  C  CB  . LEU A 1 757 ? 202.566 216.500 149.361 1.00 51.38  ? 757 LEU A CB  1 
ATOM   5853  C  CG  . LEU A 1 757 ? 203.899 217.193 149.625 1.00 54.82  ? 757 LEU A CG  1 
ATOM   5854  C  CD1 . LEU A 1 757 ? 204.117 217.397 151.111 1.00 53.68  ? 757 LEU A CD1 1 
ATOM   5855  C  CD2 . LEU A 1 757 ? 205.026 216.388 149.026 1.00 56.19  ? 757 LEU A CD2 1 
ATOM   5856  N  N   . THR A 1 758 ? 200.741 214.378 147.529 1.00 55.18  ? 758 THR A N   1 
ATOM   5857  C  CA  . THR A 1 758 ? 199.477 213.708 147.232 1.00 47.71  ? 758 THR A CA  1 
ATOM   5858  C  C   . THR A 1 758 ? 198.866 213.218 148.535 1.00 42.40  ? 758 THR A C   1 
ATOM   5859  O  O   . THR A 1 758 ? 199.111 212.100 148.970 1.00 45.99  ? 758 THR A O   1 
ATOM   5860  C  CB  . THR A 1 758 ? 199.712 212.556 146.265 1.00 49.56  ? 758 THR A CB  1 
ATOM   5861  O  OG1 . THR A 1 758 ? 200.699 212.933 145.295 1.00 54.06  ? 758 THR A OG1 1 
ATOM   5862  C  CG2 . THR A 1 758 ? 198.426 212.146 145.576 1.00 55.52  ? 758 THR A CG2 1 
ATOM   5863  N  N   . VAL A 1 759 ? 198.063 214.067 149.170 1.00 42.83  ? 759 VAL A N   1 
ATOM   5864  C  CA  . VAL A 1 759 ? 197.384 213.641 150.383 1.00 45.59  ? 759 VAL A CA  1 
ATOM   5865  C  C   . VAL A 1 759 ? 196.519 212.429 150.070 1.00 55.33  ? 759 VAL A C   1 
ATOM   5866  O  O   . VAL A 1 759 ? 195.834 212.384 149.045 1.00 59.92  ? 759 VAL A O   1 
ATOM   5867  C  CB  . VAL A 1 759 ? 196.548 214.792 150.965 1.00 44.61  ? 759 VAL A CB  1 
ATOM   5868  C  CG1 . VAL A 1 759 ? 195.787 214.334 152.183 1.00 38.12  ? 759 VAL A CG1 1 
ATOM   5869  C  CG2 . VAL A 1 759 ? 197.445 215.965 151.314 1.00 52.61  ? 759 VAL A CG2 1 
ATOM   5870  N  N   . VAL A 1 760 ? 196.580 211.419 150.937 1.00 56.22  ? 760 VAL A N   1 
ATOM   5871  C  CA  . VAL A 1 760 ? 195.754 210.225 150.814 1.00 45.25  ? 760 VAL A CA  1 
ATOM   5872  C  C   . VAL A 1 760 ? 195.011 210.034 152.121 1.00 41.75  ? 760 VAL A C   1 
ATOM   5873  O  O   . VAL A 1 760 ? 195.466 210.466 153.183 1.00 51.40  ? 760 VAL A O   1 
ATOM   5874  C  CB  . VAL A 1 760 ? 196.573 208.963 150.488 1.00 43.77  ? 760 VAL A CB  1 
ATOM   5875  C  CG1 . VAL A 1 760 ? 195.665 207.862 150.012 1.00 49.47  ? 760 VAL A CG1 1 
ATOM   5876  C  CG2 . VAL A 1 760 ? 197.626 209.251 149.449 1.00 46.02  ? 760 VAL A CG2 1 
ATOM   5877  N  N   . ALA A 1 761 ? 193.859 209.390 152.044 1.00 37.46  ? 761 ALA A N   1 
ATOM   5878  C  CA  . ALA A 1 761 ? 193.066 209.089 153.221 1.00 45.41  ? 761 ALA A CA  1 
ATOM   5879  C  C   . ALA A 1 761 ? 192.867 207.586 153.306 1.00 56.99  ? 761 ALA A C   1 
ATOM   5880  O  O   . ALA A 1 761 ? 192.554 206.942 152.300 1.00 63.59  ? 761 ALA A O   1 
ATOM   5881  C  CB  . ALA A 1 761 ? 191.717 209.796 153.176 1.00 47.93  ? 761 ALA A CB  1 
ATOM   5882  N  N   . GLU A 1 762 ? 193.045 207.027 154.497 1.00 54.80  ? 762 GLU A N   1 
ATOM   5883  C  CA  . GLU A 1 762 ? 192.798 205.614 154.726 1.00 53.98  ? 762 GLU A CA  1 
ATOM   5884  C  C   . GLU A 1 762 ? 191.628 205.463 155.684 1.00 56.47  ? 762 GLU A C   1 
ATOM   5885  O  O   . GLU A 1 762 ? 191.486 206.245 156.629 1.00 60.20  ? 762 GLU A O   1 
ATOM   5886  C  CB  . GLU A 1 762 ? 194.046 204.915 155.266 1.00 58.34  ? 762 GLU A CB  1 
ATOM   5887  C  CG  . GLU A 1 762 ? 194.279 205.077 156.752 1.00 65.46  ? 762 GLU A CG  1 
ATOM   5888  C  CD  . GLU A 1 762 ? 195.596 204.478 157.201 1.00 71.31  ? 762 GLU A CD  1 
ATOM   5889  O  OE1 . GLU A 1 762 ? 195.789 203.257 157.027 1.00 76.92  ? 762 GLU A OE1 1 
ATOM   5890  O  OE2 . GLU A 1 762 ? 196.441 205.232 157.727 1.00 69.37  ? 762 GLU A OE2 1 
ATOM   5891  N  N   . GLY A 1 763 ? 190.772 204.488 155.413 1.00 52.73  ? 763 GLY A N   1 
ATOM   5892  C  CA  . GLY A 1 763 ? 189.650 204.210 156.275 1.00 54.64  ? 763 GLY A CA  1 
ATOM   5893  C  C   . GLY A 1 763 ? 188.402 205.026 156.039 1.00 58.16  ? 763 GLY A C   1 
ATOM   5894  O  O   . GLY A 1 763 ? 187.538 205.061 156.920 1.00 64.29  ? 763 GLY A O   1 
ATOM   5895  N  N   . VAL A 1 764 ? 188.264 205.685 154.890 1.00 52.58  ? 764 VAL A N   1 
ATOM   5896  C  CA  . VAL A 1 764 ? 187.023 206.389 154.601 1.00 53.36  ? 764 VAL A CA  1 
ATOM   5897  C  C   . VAL A 1 764 ? 185.911 205.368 154.417 1.00 63.97  ? 764 VAL A C   1 
ATOM   5898  O  O   . VAL A 1 764 ? 186.079 204.365 153.714 1.00 68.48  ? 764 VAL A O   1 
ATOM   5899  C  CB  . VAL A 1 764 ? 187.178 207.281 153.367 1.00 53.15  ? 764 VAL A CB  1 
ATOM   5900  C  CG1 . VAL A 1 764 ? 185.904 208.045 153.120 1.00 64.07  ? 764 VAL A CG1 1 
ATOM   5901  C  CG2 . VAL A 1 764 ? 188.337 208.234 153.559 1.00 58.04  ? 764 VAL A CG2 1 
ATOM   5902  N  N   . GLU A 1 765 ? 184.769 205.613 155.055 1.00 69.22  ? 765 GLU A N   1 
ATOM   5903  C  CA  . GLU A 1 765 ? 183.696 204.631 155.145 1.00 69.32  ? 765 GLU A CA  1 
ATOM   5904  C  C   . GLU A 1 765 ? 182.451 205.005 154.357 1.00 71.86  ? 765 GLU A C   1 
ATOM   5905  O  O   . GLU A 1 765 ? 181.995 204.219 153.525 1.00 68.77  ? 765 GLU A O   1 
ATOM   5906  C  CB  . GLU A 1 765 ? 183.319 204.415 156.616 1.00 68.46  ? 765 GLU A CB  1 
ATOM   5907  C  CG  . GLU A 1 765 ? 183.840 203.139 157.242 1.00 71.09  ? 765 GLU A CG  1 
ATOM   5908  C  CD  . GLU A 1 765 ? 183.790 201.945 156.310 1.00 76.09  ? 765 GLU A CD  1 
ATOM   5909  O  OE1 . GLU A 1 765 ? 182.774 201.772 155.602 1.00 78.58  ? 765 GLU A OE1 1 
ATOM   5910  O  OE2 . GLU A 1 765 ? 184.770 201.173 156.287 1.00 77.82  ? 765 GLU A OE2 1 
ATOM   5911  N  N   . THR A 1 766 ? 181.874 206.176 154.605 1.00 78.50  ? 766 THR A N   1 
ATOM   5912  C  CA  . THR A 1 766 ? 180.555 206.514 154.089 1.00 80.02  ? 766 THR A CA  1 
ATOM   5913  C  C   . THR A 1 766 ? 180.664 207.569 152.991 1.00 77.25  ? 766 THR A C   1 
ATOM   5914  O  O   . THR A 1 766 ? 181.755 207.986 152.601 1.00 76.06  ? 766 THR A O   1 
ATOM   5915  C  CB  . THR A 1 766 ? 179.641 207.006 155.211 1.00 84.12  ? 766 THR A CB  1 
ATOM   5916  O  OG1 . THR A 1 766 ? 179.812 208.418 155.379 1.00 80.51  ? 766 THR A OG1 1 
ATOM   5917  C  CG2 . THR A 1 766 ? 179.978 206.304 156.517 1.00 86.00  ? 766 THR A CG2 1 
ATOM   5918  N  N   . LYS A 1 767 ? 179.506 207.992 152.489 1.00 80.55  ? 767 LYS A N   1 
ATOM   5919  C  CA  . LYS A 1 767 ? 179.458 208.930 151.374 1.00 86.96  ? 767 LYS A CA  1 
ATOM   5920  C  C   . LYS A 1 767 ? 179.747 210.354 151.825 1.00 90.57  ? 767 LYS A C   1 
ATOM   5921  O  O   . LYS A 1 767 ? 180.393 211.121 151.100 1.00 93.17  ? 767 LYS A O   1 
ATOM   5922  C  CB  . LYS A 1 767 ? 178.094 208.842 150.687 1.00 89.86  ? 767 LYS A CB  1 
ATOM   5923  C  CG  . LYS A 1 767 ? 177.710 210.058 149.863 1.00 91.80  ? 767 LYS A CG  1 
ATOM   5924  C  CD  . LYS A 1 767 ? 178.505 210.095 148.570 1.00 92.29  ? 767 LYS A CD  1 
ATOM   5925  C  CE  . LYS A 1 767 ? 177.738 209.438 147.437 1.00 96.06  ? 767 LYS A CE  1 
ATOM   5926  N  NZ  . LYS A 1 767 ? 178.248 209.869 146.109 1.00 97.91  ? 767 LYS A NZ  1 
ATOM   5927  N  N   . GLU A 1 768 ? 179.278 210.717 153.017 1.00 89.71  ? 768 GLU A N   1 
ATOM   5928  C  CA  . GLU A 1 768 ? 179.460 212.078 153.504 1.00 90.18  ? 768 GLU A CA  1 
ATOM   5929  C  C   . GLU A 1 768 ? 180.935 212.403 153.674 1.00 85.79  ? 768 GLU A C   1 
ATOM   5930  O  O   . GLU A 1 768 ? 181.389 213.490 153.296 1.00 81.88  ? 768 GLU A O   1 
ATOM   5931  C  CB  . GLU A 1 768 ? 178.716 212.251 154.828 1.00 93.32  ? 768 GLU A CB  1 
ATOM   5932  C  CG  . GLU A 1 768 ? 177.234 211.913 154.749 1.00 96.72  ? 768 GLU A CG  1 
ATOM   5933  C  CD  . GLU A 1 768 ? 176.978 210.416 154.798 1.00 94.41  ? 768 GLU A CD  1 
ATOM   5934  O  OE1 . GLU A 1 768 ? 177.923 209.660 155.109 1.00 89.12  ? 768 GLU A OE1 1 
ATOM   5935  O  OE2 . GLU A 1 768 ? 175.838 209.996 154.512 1.00 93.11  ? 768 GLU A OE2 1 
ATOM   5936  N  N   . GLN A 1 769 ? 181.696 211.465 154.241 1.00 84.33  ? 769 GLN A N   1 
ATOM   5937  C  CA  . GLN A 1 769 ? 183.125 211.672 154.415 1.00 79.52  ? 769 GLN A CA  1 
ATOM   5938  C  C   . GLN A 1 769 ? 183.808 211.878 153.078 1.00 78.81  ? 769 GLN A C   1 
ATOM   5939  O  O   . GLN A 1 769 ? 184.639 212.779 152.932 1.00 83.92  ? 769 GLN A O   1 
ATOM   5940  C  CB  . GLN A 1 769 ? 183.740 210.481 155.142 1.00 76.12  ? 769 GLN A CB  1 
ATOM   5941  C  CG  . GLN A 1 769 ? 183.356 210.392 156.595 1.00 78.17  ? 769 GLN A CG  1 
ATOM   5942  C  CD  . GLN A 1 769 ? 183.797 209.092 157.219 1.00 77.07  ? 769 GLN A CD  1 
ATOM   5943  O  OE1 . GLN A 1 769 ? 184.110 208.132 156.517 1.00 75.46  ? 769 GLN A OE1 1 
ATOM   5944  N  NE2 . GLN A 1 769 ? 183.832 209.050 158.546 1.00 78.53  ? 769 GLN A NE2 1 
ATOM   5945  N  N   . PHE A 1 770 ? 183.464 211.060 152.089 1.00 76.37  ? 770 PHE A N   1 
ATOM   5946  C  CA  . PHE A 1 770 ? 184.082 211.186 150.777 1.00 75.89  ? 770 PHE A CA  1 
ATOM   5947  C  C   . PHE A 1 770 ? 183.755 212.531 150.149 1.00 80.35  ? 770 PHE A C   1 
ATOM   5948  O  O   . PHE A 1 770 ? 184.635 213.209 149.606 1.00 84.33  ? 770 PHE A O   1 
ATOM   5949  C  CB  . PHE A 1 770 ? 183.617 210.046 149.883 1.00 74.41  ? 770 PHE A CB  1 
ATOM   5950  C  CG  . PHE A 1 770 ? 183.988 210.212 148.455 1.00 70.74  ? 770 PHE A CG  1 
ATOM   5951  C  CD1 . PHE A 1 770 ? 185.307 210.305 148.086 1.00 67.74  ? 770 PHE A CD1 1 
ATOM   5952  C  CD2 . PHE A 1 770 ? 183.018 210.272 147.480 1.00 79.74  ? 770 PHE A CD2 1 
ATOM   5953  C  CE1 . PHE A 1 770 ? 185.655 210.448 146.771 1.00 72.30  ? 770 PHE A CE1 1 
ATOM   5954  C  CE2 . PHE A 1 770 ? 183.360 210.420 146.159 1.00 82.51  ? 770 PHE A CE2 1 
ATOM   5955  C  CZ  . PHE A 1 770 ? 184.682 210.506 145.804 1.00 79.00  ? 770 PHE A CZ  1 
ATOM   5956  N  N   . GLU A 1 771 ? 182.490 212.948 150.235 1.00 83.38  ? 771 GLU A N   1 
ATOM   5957  C  CA  . GLU A 1 771 ? 182.083 214.210 149.626 1.00 85.27  ? 771 GLU A CA  1 
ATOM   5958  C  C   . GLU A 1 771 ? 182.778 215.393 150.287 1.00 85.73  ? 771 GLU A C   1 
ATOM   5959  O  O   . GLU A 1 771 ? 183.294 216.289 149.605 1.00 85.10  ? 771 GLU A O   1 
ATOM   5960  C  CB  . GLU A 1 771 ? 180.564 214.365 149.710 1.00 89.32  ? 771 GLU A CB  1 
ATOM   5961  C  CG  . GLU A 1 771 ? 179.800 213.549 148.679 1.00 95.74  ? 771 GLU A CG  1 
ATOM   5962  C  CD  . GLU A 1 771 ? 179.840 214.172 147.297 1.00 101.65 ? 771 GLU A CD  1 
ATOM   5963  O  OE1 . GLU A 1 771 ? 180.082 215.394 147.201 1.00 99.30  ? 771 GLU A OE1 1 
ATOM   5964  O  OE2 . GLU A 1 771 ? 179.629 213.441 146.307 1.00 101.74 ? 771 GLU A OE2 1 
ATOM   5965  N  N   . MET A 1 772 ? 182.820 215.409 151.620 1.00 88.43  ? 772 MET A N   1 
ATOM   5966  C  CA  . MET A 1 772 ? 183.403 216.557 152.304 1.00 87.30  ? 772 MET A CA  1 
ATOM   5967  C  C   . MET A 1 772 ? 184.923 216.555 152.212 1.00 79.63  ? 772 MET A C   1 
ATOM   5968  O  O   . MET A 1 772 ? 185.537 217.625 152.241 1.00 76.39  ? 772 MET A O   1 
ATOM   5969  C  CB  . MET A 1 772 ? 182.904 216.604 153.755 1.00 88.46  ? 772 MET A CB  1 
ATOM   5970  C  CG  . MET A 1 772 ? 183.820 217.212 154.815 1.00 84.39  ? 772 MET A CG  1 
ATOM   5971  S  SD  . MET A 1 772 ? 185.302 216.286 155.234 1.00 92.32  ? 772 MET A SD  1 
ATOM   5972  C  CE  . MET A 1 772 ? 184.608 215.113 156.382 1.00 88.87  ? 772 MET A CE  1 
ATOM   5973  N  N   . LEU A 1 773 ? 185.549 215.381 152.098 1.00 78.49  ? 773 LEU A N   1 
ATOM   5974  C  CA  . LEU A 1 773 ? 186.975 215.348 151.804 1.00 74.28  ? 773 LEU A CA  1 
ATOM   5975  C  C   . LEU A 1 773 ? 187.248 215.855 150.400 1.00 75.47  ? 773 LEU A C   1 
ATOM   5976  O  O   . LEU A 1 773 ? 188.271 216.506 150.157 1.00 80.60  ? 773 LEU A O   1 
ATOM   5977  C  CB  . LEU A 1 773 ? 187.534 213.938 151.979 1.00 68.84  ? 773 LEU A CB  1 
ATOM   5978  C  CG  . LEU A 1 773 ? 188.496 213.774 153.155 1.00 69.45  ? 773 LEU A CG  1 
ATOM   5979  C  CD1 . LEU A 1 773 ? 187.789 214.005 154.467 1.00 75.04  ? 773 LEU A CD1 1 
ATOM   5980  C  CD2 . LEU A 1 773 ? 189.132 212.422 153.146 1.00 66.08  ? 773 LEU A CD2 1 
ATOM   5981  N  N   . ARG A 1 774 ? 186.352 215.560 149.457 1.00 75.81  ? 774 ARG A N   1 
ATOM   5982  C  CA  . ARG A 1 774 ? 186.473 216.165 148.138 1.00 76.47  ? 774 ARG A CA  1 
ATOM   5983  C  C   . ARG A 1 774 ? 186.317 217.673 148.225 1.00 78.47  ? 774 ARG A C   1 
ATOM   5984  O  O   . ARG A 1 774 ? 186.922 218.408 147.436 1.00 77.89  ? 774 ARG A O   1 
ATOM   5985  C  CB  . ARG A 1 774 ? 185.438 215.570 147.181 1.00 77.91  ? 774 ARG A CB  1 
ATOM   5986  C  CG  . ARG A 1 774 ? 185.511 216.126 145.763 1.00 77.37  ? 774 ARG A CG  1 
ATOM   5987  C  CD  . ARG A 1 774 ? 184.284 215.756 144.942 1.00 79.44  ? 774 ARG A CD  1 
ATOM   5988  N  NE  . ARG A 1 774 ? 184.415 214.454 144.300 1.00 82.37  ? 774 ARG A NE  1 
ATOM   5989  C  CZ  . ARG A 1 774 ? 183.477 213.896 143.547 1.00 85.98  ? 774 ARG A CZ  1 
ATOM   5990  N  NH1 . ARG A 1 774 ? 182.330 214.508 143.306 1.00 90.80  ? 774 ARG A NH1 1 
ATOM   5991  N  NH2 . ARG A 1 774 ? 183.695 212.693 143.024 1.00 85.86  ? 774 ARG A NH2 1 
ATOM   5992  N  N   . LYS A 1 775 ? 185.516 218.150 149.180 1.00 78.64  ? 775 LYS A N   1 
ATOM   5993  C  CA  . LYS A 1 775 ? 185.368 219.590 149.372 1.00 80.09  ? 775 LYS A CA  1 
ATOM   5994  C  C   . LYS A 1 775 ? 186.679 220.245 149.792 1.00 78.56  ? 775 LYS A C   1 
ATOM   5995  O  O   . LYS A 1 775 ? 186.927 221.405 149.447 1.00 75.35  ? 775 LYS A O   1 
ATOM   5996  C  CB  . LYS A 1 775 ? 184.279 219.869 150.405 1.00 80.98  ? 775 LYS A CB  1 
ATOM   5997  C  CG  . LYS A 1 775 ? 183.936 221.340 150.562 1.00 84.84  ? 775 LYS A CG  1 
ATOM   5998  C  CD  . LYS A 1 775 ? 182.723 221.537 151.458 1.00 88.07  ? 775 LYS A CD  1 
ATOM   5999  C  CE  . LYS A 1 775 ? 182.847 220.742 152.747 1.00 88.26  ? 775 LYS A CE  1 
ATOM   6000  N  NZ  . LYS A 1 775 ? 182.448 221.549 153.933 1.00 94.81  ? 775 LYS A NZ  1 
ATOM   6001  N  N   . ILE A 1 776 ? 187.529 219.531 150.527 1.00 77.07  ? 776 ILE A N   1 
ATOM   6002  C  CA  . ILE A 1 776 ? 188.823 220.050 150.952 1.00 71.39  ? 776 ILE A CA  1 
ATOM   6003  C  C   . ILE A 1 776 ? 189.967 219.434 150.163 1.00 67.68  ? 776 ILE A C   1 
ATOM   6004  O  O   . ILE A 1 776 ? 191.123 219.539 150.573 1.00 66.24  ? 776 ILE A O   1 
ATOM   6005  C  CB  . ILE A 1 776 ? 189.036 219.868 152.462 1.00 71.96  ? 776 ILE A CB  1 
ATOM   6006  C  CG1 . ILE A 1 776 ? 189.127 218.395 152.828 1.00 69.46  ? 776 ILE A CG1 1 
ATOM   6007  C  CG2 . ILE A 1 776 ? 187.905 220.516 153.238 1.00 75.15  ? 776 ILE A CG2 1 
ATOM   6008  C  CD1 . ILE A 1 776 ? 189.140 218.166 154.309 1.00 69.49  ? 776 ILE A CD1 1 
ATOM   6009  N  N   . HIS A 1 777 ? 189.666 218.783 149.043 1.00 71.45  ? 777 HIS A N   1 
ATOM   6010  C  CA  . HIS A 1 777 ? 190.668 218.281 148.106 1.00 73.68  ? 777 HIS A CA  1 
ATOM   6011  C  C   . HIS A 1 777 ? 191.638 217.306 148.776 1.00 74.48  ? 777 HIS A C   1 
ATOM   6012  O  O   . HIS A 1 777 ? 192.835 217.569 148.905 1.00 77.97  ? 777 HIS A O   1 
ATOM   6013  C  CB  . HIS A 1 777 ? 191.427 219.436 147.444 1.00 72.43  ? 777 HIS A CB  1 
ATOM   6014  C  CG  . HIS A 1 777 ? 190.542 220.473 146.832 1.00 74.56  ? 777 HIS A CG  1 
ATOM   6015  N  ND1 . HIS A 1 777 ? 190.983 221.745 146.541 1.00 73.84  ? 777 HIS A ND1 1 
ATOM   6016  C  CD2 . HIS A 1 777 ? 189.243 220.429 146.457 1.00 77.47  ? 777 HIS A CD2 1 
ATOM   6017  C  CE1 . HIS A 1 777 ? 189.992 222.441 146.013 1.00 76.60  ? 777 HIS A CE1 1 
ATOM   6018  N  NE2 . HIS A 1 777 ? 188.926 221.666 145.951 1.00 80.68  ? 777 HIS A NE2 1 
ATOM   6019  N  N   . CYS A 1 778 ? 191.102 216.161 149.206 1.00 70.56  ? 778 CYS A N   1 
ATOM   6020  C  CA  . CYS A 1 778 ? 191.969 215.106 149.709 1.00 61.59  ? 778 CYS A CA  1 
ATOM   6021  C  C   . CYS A 1 778 ? 192.653 214.354 148.580 1.00 57.79  ? 778 CYS A C   1 
ATOM   6022  O  O   . CYS A 1 778 ? 193.775 213.881 148.763 1.00 60.93  ? 778 CYS A O   1 
ATOM   6023  C  CB  . CYS A 1 778 ? 191.183 214.141 150.587 1.00 61.37  ? 778 CYS A CB  1 
ATOM   6024  S  SG  . CYS A 1 778 ? 191.903 212.499 150.711 1.00 65.68  ? 778 CYS A SG  1 
ATOM   6025  N  N   . ARG A 1 779 ? 191.995 214.246 147.430 1.00 57.61  ? 779 ARG A N   1 
ATOM   6026  C  CA  . ARG A 1 779 ? 192.552 213.867 146.133 1.00 58.64  ? 779 ARG A CA  1 
ATOM   6027  C  C   . ARG A 1 779 ? 192.784 212.370 145.896 1.00 61.01  ? 779 ARG A C   1 
ATOM   6028  O  O   . ARG A 1 779 ? 192.906 211.965 144.737 1.00 63.65  ? 779 ARG A O   1 
ATOM   6029  C  CB  . ARG A 1 779 ? 193.852 214.656 145.924 1.00 54.86  ? 779 ARG A CB  1 
ATOM   6030  C  CG  . ARG A 1 779 ? 194.771 214.166 144.843 1.00 58.05  ? 779 ARG A CG  1 
ATOM   6031  C  CD  . ARG A 1 779 ? 196.115 214.860 144.917 1.00 66.02  ? 779 ARG A CD  1 
ATOM   6032  N  NE  . ARG A 1 779 ? 197.061 214.445 143.883 1.00 73.86  ? 779 ARG A NE  1 
ATOM   6033  C  CZ  . ARG A 1 779 ? 196.821 214.402 142.578 1.00 76.64  ? 779 ARG A CZ  1 
ATOM   6034  N  NH1 . ARG A 1 779 ? 195.683 214.835 142.061 1.00 81.38  ? 779 ARG A NH1 1 
ATOM   6035  N  NH2 . ARG A 1 779 ? 197.763 213.934 141.763 1.00 73.73  ? 779 ARG A NH2 1 
ATOM   6036  N  N   . VAL A 1 780 ? 192.707 211.527 146.930 1.00 62.44  ? 780 VAL A N   1 
ATOM   6037  C  CA  . VAL A 1 780 ? 192.644 210.067 146.771 1.00 58.71  ? 780 VAL A CA  1 
ATOM   6038  C  C   . VAL A 1 780 ? 192.047 209.480 148.039 1.00 53.81  ? 780 VAL A C   1 
ATOM   6039  O  O   . VAL A 1 780 ? 192.390 209.889 149.148 1.00 59.85  ? 780 VAL A O   1 
ATOM   6040  C  CB  . VAL A 1 780 ? 194.023 209.421 146.464 1.00 54.87  ? 780 VAL A CB  1 
ATOM   6041  C  CG1 . VAL A 1 780 ? 194.401 209.540 145.013 1.00 54.45  ? 780 VAL A CG1 1 
ATOM   6042  C  CG2 . VAL A 1 780 ? 195.076 210.073 147.269 1.00 55.92  ? 780 VAL A CG2 1 
ATOM   6043  N  N   . ILE A 1 781 ? 191.170 208.497 147.874 1.00 47.27  ? 781 ILE A N   1 
ATOM   6044  C  CA  . ILE A 1 781 ? 190.446 207.894 148.985 1.00 50.67  ? 781 ILE A CA  1 
ATOM   6045  C  C   . ILE A 1 781 ? 190.638 206.387 148.968 1.00 60.58  ? 781 ILE A C   1 
ATOM   6046  O  O   . ILE A 1 781 ? 190.463 205.740 147.930 1.00 66.40  ? 781 ILE A O   1 
ATOM   6047  C  CB  . ILE A 1 781 ? 188.951 208.237 148.925 1.00 54.52  ? 781 ILE A CB  1 
ATOM   6048  C  CG1 . ILE A 1 781 ? 188.755 209.738 149.002 1.00 55.49  ? 781 ILE A CG1 1 
ATOM   6049  C  CG2 . ILE A 1 781 ? 188.221 207.564 150.044 1.00 58.73  ? 781 ILE A CG2 1 
ATOM   6050  C  CD1 . ILE A 1 781 ? 189.256 210.313 150.275 1.00 56.63  ? 781 ILE A CD1 1 
ATOM   6051  N  N   . GLN A 1 782 ? 190.982 205.824 150.124 1.00 56.08  ? 782 GLN A N   1 
ATOM   6052  C  CA  . GLN A 1 782 ? 191.249 204.399 150.262 1.00 48.44  ? 782 GLN A CA  1 
ATOM   6053  C  C   . GLN A 1 782 ? 190.443 203.872 151.428 1.00 50.96  ? 782 GLN A C   1 
ATOM   6054  O  O   . GLN A 1 782 ? 190.650 204.299 152.566 1.00 53.79  ? 782 GLN A O   1 
ATOM   6055  C  CB  . GLN A 1 782 ? 192.737 204.140 150.489 1.00 48.58  ? 782 GLN A CB  1 
ATOM   6056  C  CG  . GLN A 1 782 ? 193.063 202.763 150.975 1.00 52.01  ? 782 GLN A CG  1 
ATOM   6057  C  CD  . GLN A 1 782 ? 194.358 202.729 151.746 1.00 52.68  ? 782 GLN A CD  1 
ATOM   6058  O  OE1 . GLN A 1 782 ? 195.051 203.735 151.850 1.00 51.99  ? 782 GLN A OE1 1 
ATOM   6059  N  NE2 . GLN A 1 782 ? 194.701 201.568 152.278 1.00 53.27  ? 782 GLN A NE2 1 
ATOM   6060  N  N   . GLY A 1 783 ? 189.537 202.946 151.157 1.00 52.46  ? 783 GLY A N   1 
ATOM   6061  C  CA  . GLY A 1 783 ? 188.765 202.370 152.233 1.00 61.65  ? 783 GLY A CA  1 
ATOM   6062  C  C   . GLY A 1 783 ? 187.693 201.446 151.701 1.00 67.64  ? 783 GLY A C   1 
ATOM   6063  O  O   . GLY A 1 783 ? 187.607 201.180 150.502 1.00 67.68  ? 783 GLY A O   1 
ATOM   6064  N  N   . TYR A 1 784 ? 186.870 200.974 152.632 1.00 71.16  ? 784 TYR A N   1 
ATOM   6065  C  CA  . TYR A 1 784 ? 185.796 200.057 152.303 1.00 73.79  ? 784 TYR A CA  1 
ATOM   6066  C  C   . TYR A 1 784 ? 184.716 200.714 151.457 1.00 74.52  ? 784 TYR A C   1 
ATOM   6067  O  O   . TYR A 1 784 ? 183.881 200.004 150.887 1.00 80.88  ? 784 TYR A O   1 
ATOM   6068  C  CB  . TYR A 1 784 ? 185.184 199.505 153.592 1.00 74.26  ? 784 TYR A CB  1 
ATOM   6069  C  CG  . TYR A 1 784 ? 186.112 198.618 154.397 1.00 75.20  ? 784 TYR A CG  1 
ATOM   6070  C  CD1 . TYR A 1 784 ? 187.036 199.165 155.274 1.00 79.63  ? 784 TYR A CD1 1 
ATOM   6071  C  CD2 . TYR A 1 784 ? 186.055 197.238 154.288 1.00 75.62  ? 784 TYR A CD2 1 
ATOM   6072  C  CE1 . TYR A 1 784 ? 187.884 198.362 156.016 1.00 83.87  ? 784 TYR A CE1 1 
ATOM   6073  C  CE2 . TYR A 1 784 ? 186.898 196.425 155.024 1.00 81.56  ? 784 TYR A CE2 1 
ATOM   6074  C  CZ  . TYR A 1 784 ? 187.810 196.992 155.887 1.00 87.36  ? 784 TYR A CZ  1 
ATOM   6075  O  OH  . TYR A 1 784 ? 188.651 196.189 156.622 1.00 86.05  ? 784 TYR A OH  1 
ATOM   6076  N  N   . PHE A 1 785 ? 184.714 202.043 151.356 1.00 65.72  ? 785 PHE A N   1 
ATOM   6077  C  CA  . PHE A 1 785 ? 183.645 202.730 150.653 1.00 64.68  ? 785 PHE A CA  1 
ATOM   6078  C  C   . PHE A 1 785 ? 183.666 202.437 149.166 1.00 67.82  ? 785 PHE A C   1 
ATOM   6079  O  O   . PHE A 1 785 ? 182.617 202.499 148.521 1.00 73.85  ? 785 PHE A O   1 
ATOM   6080  C  CB  . PHE A 1 785 ? 183.729 204.228 150.949 1.00 71.32  ? 785 PHE A CB  1 
ATOM   6081  C  CG  . PHE A 1 785 ? 182.766 205.074 150.166 1.00 76.22  ? 785 PHE A CG  1 
ATOM   6082  C  CD1 . PHE A 1 785 ? 183.018 205.448 148.865 1.00 75.86  ? 785 PHE A CD1 1 
ATOM   6083  C  CD2 . PHE A 1 785 ? 181.572 205.452 150.730 1.00 78.33  ? 785 PHE A CD2 1 
ATOM   6084  C  CE1 . PHE A 1 785 ? 182.117 206.219 148.169 1.00 78.15  ? 785 PHE A CE1 1 
ATOM   6085  C  CE2 . PHE A 1 785 ? 180.674 206.204 150.029 1.00 78.93  ? 785 PHE A CE2 1 
ATOM   6086  C  CZ  . PHE A 1 785 ? 180.946 206.590 148.752 1.00 80.16  ? 785 PHE A CZ  1 
ATOM   6087  N  N   . PHE A 1 786 ? 184.817 202.091 148.614 1.00 69.69  ? 786 PHE A N   1 
ATOM   6088  C  CA  . PHE A 1 786 ? 184.884 201.607 147.244 1.00 76.77  ? 786 PHE A CA  1 
ATOM   6089  C  C   . PHE A 1 786 ? 185.129 200.114 147.141 1.00 79.46  ? 786 PHE A C   1 
ATOM   6090  O  O   . PHE A 1 786 ? 184.598 199.482 146.224 1.00 78.48  ? 786 PHE A O   1 
ATOM   6091  C  CB  . PHE A 1 786 ? 185.978 202.343 146.466 1.00 74.26  ? 786 PHE A CB  1 
ATOM   6092  C  CG  . PHE A 1 786 ? 185.894 203.828 146.579 1.00 72.94  ? 786 PHE A CG  1 
ATOM   6093  C  CD1 . PHE A 1 786 ? 184.826 204.513 146.046 1.00 74.78  ? 786 PHE A CD1 1 
ATOM   6094  C  CD2 . PHE A 1 786 ? 186.877 204.537 147.234 1.00 72.66  ? 786 PHE A CD2 1 
ATOM   6095  C  CE1 . PHE A 1 786 ? 184.751 205.887 146.147 1.00 77.34  ? 786 PHE A CE1 1 
ATOM   6096  C  CE2 . PHE A 1 786 ? 186.805 205.908 147.341 1.00 73.63  ? 786 PHE A CE2 1 
ATOM   6097  C  CZ  . PHE A 1 786 ? 185.740 206.584 146.798 1.00 76.53  ? 786 PHE A CZ  1 
ATOM   6098  N  N   . SER A 1 787 ? 185.914 199.534 148.048 1.00 76.88  ? 787 SER A N   1 
ATOM   6099  C  CA  . SER A 1 787 ? 186.171 198.102 148.034 1.00 69.44  ? 787 SER A CA  1 
ATOM   6100  C  C   . SER A 1 787 ? 186.799 197.645 149.337 1.00 65.70  ? 787 SER A C   1 
ATOM   6101  O  O   . SER A 1 787 ? 187.750 198.262 149.823 1.00 65.69  ? 787 SER A O   1 
ATOM   6102  C  CB  . SER A 1 787 ? 187.098 197.726 146.882 1.00 65.97  ? 787 SER A CB  1 
ATOM   6103  O  OG  . SER A 1 787 ? 188.206 198.599 146.849 1.00 63.87  ? 787 SER A OG  1 
ATOM   6104  N  N   . ARG A 1 788 ? 186.287 196.560 149.902 1.00 65.73  ? 788 ARG A N   1 
ATOM   6105  C  CA  . ARG A 1 788 ? 187.025 195.869 150.931 1.00 65.79  ? 788 ARG A CA  1 
ATOM   6106  C  C   . ARG A 1 788 ? 188.284 195.291 150.297 1.00 61.00  ? 788 ARG A C   1 
ATOM   6107  O  O   . ARG A 1 788 ? 188.337 195.096 149.081 1.00 59.16  ? 788 ARG A O   1 
ATOM   6108  C  CB  . ARG A 1 788 ? 186.180 194.757 151.538 1.00 67.39  ? 788 ARG A CB  1 
ATOM   6109  C  CG  . ARG A 1 788 ? 184.771 195.167 151.886 1.00 71.26  ? 788 ARG A CG  1 
ATOM   6110  C  CD  . ARG A 1 788 ? 183.743 194.017 152.018 1.00 76.42  ? 788 ARG A CD  1 
ATOM   6111  N  NE  . ARG A 1 788 ? 183.602 193.128 150.864 1.00 76.67  ? 788 ARG A NE  1 
ATOM   6112  C  CZ  . ARG A 1 788 ? 184.479 192.215 150.464 1.00 75.32  ? 788 ARG A CZ  1 
ATOM   6113  N  NH1 . ARG A 1 788 ? 185.521 191.876 151.206 1.00 73.34  ? 788 ARG A NH1 1 
ATOM   6114  N  NH2 . ARG A 1 788 ? 184.273 191.581 149.313 1.00 75.44  ? 788 ARG A NH2 1 
ATOM   6115  N  N   . PRO A 1 789 ? 189.313 195.033 151.080 1.00 53.27  ? 789 PRO A N   1 
ATOM   6116  C  CA  . PRO A 1 789 ? 190.524 194.449 150.501 1.00 47.12  ? 789 PRO A CA  1 
ATOM   6117  C  C   . PRO A 1 789 ? 190.231 193.116 149.841 1.00 50.85  ? 789 PRO A C   1 
ATOM   6118  O  O   . PRO A 1 789 ? 189.852 192.157 150.516 1.00 55.26  ? 789 PRO A O   1 
ATOM   6119  C  CB  . PRO A 1 789 ? 191.445 194.289 151.713 1.00 49.59  ? 789 PRO A CB  1 
ATOM   6120  C  CG  . PRO A 1 789 ? 190.951 195.261 152.695 1.00 55.76  ? 789 PRO A CG  1 
ATOM   6121  C  CD  . PRO A 1 789 ? 189.476 195.335 152.508 1.00 56.62  ? 789 PRO A CD  1 
ATOM   6122  N  N   . LEU A 1 790 ? 190.384 193.044 148.538 1.00 51.59  ? 790 LEU A N   1 
ATOM   6123  C  CA  . LEU A 1 790 ? 189.998 191.832 147.839 1.00 51.44  ? 790 LEU A CA  1 
ATOM   6124  C  C   . LEU A 1 790 ? 191.147 190.846 147.787 1.00 52.32  ? 790 LEU A C   1 
ATOM   6125  O  O   . LEU A 1 790 ? 192.318 191.231 147.838 1.00 53.96  ? 790 LEU A O   1 
ATOM   6126  C  CB  . LEU A 1 790 ? 189.558 192.158 146.420 1.00 49.34  ? 790 LEU A CB  1 
ATOM   6127  C  CG  . LEU A 1 790 ? 188.847 193.476 146.175 1.00 55.97  ? 790 LEU A CG  1 
ATOM   6128  C  CD1 . LEU A 1 790 ? 188.938 193.807 144.710 1.00 56.62  ? 790 LEU A CD1 1 
ATOM   6129  C  CD2 . LEU A 1 790 ? 187.398 193.374 146.601 1.00 64.19  ? 790 LEU A CD2 1 
ATOM   6130  N  N   . PRO A 1 791 ? 190.841 189.558 147.661 1.00 47.66  ? 791 PRO A N   1 
ATOM   6131  C  CA  . PRO A 1 791 ? 191.892 188.576 147.397 1.00 44.26  ? 791 PRO A CA  1 
ATOM   6132  C  C   . PRO A 1 791 ? 192.604 188.874 146.089 1.00 43.71  ? 791 PRO A C   1 
ATOM   6133  O  O   . PRO A 1 791 ? 192.078 189.535 145.195 1.00 48.04  ? 791 PRO A O   1 
ATOM   6134  C  CB  . PRO A 1 791 ? 191.136 187.245 147.335 1.00 47.24  ? 791 PRO A CB  1 
ATOM   6135  C  CG  . PRO A 1 791 ? 189.697 187.604 147.254 1.00 50.07  ? 791 PRO A CG  1 
ATOM   6136  C  CD  . PRO A 1 791 ? 189.543 188.922 147.910 1.00 47.55  ? 791 PRO A CD  1 
ATOM   6137  N  N   . ALA A 1 792 ? 193.825 188.358 145.985 1.00 42.85  ? 792 ALA A N   1 
ATOM   6138  C  CA  . ALA A 1 792 ? 194.735 188.758 144.925 1.00 44.07  ? 792 ALA A CA  1 
ATOM   6139  C  C   . ALA A 1 792 ? 194.227 188.409 143.541 1.00 46.01  ? 792 ALA A C   1 
ATOM   6140  O  O   . ALA A 1 792 ? 194.745 188.949 142.561 1.00 49.01  ? 792 ALA A O   1 
ATOM   6141  C  CB  . ALA A 1 792 ? 196.100 188.107 145.138 1.00 43.61  ? 792 ALA A CB  1 
ATOM   6142  N  N   . GLU A 1 793 ? 193.235 187.533 143.434 1.00 49.21  ? 793 GLU A N   1 
ATOM   6143  C  CA  . GLU A 1 793 ? 192.806 187.024 142.141 1.00 57.15  ? 793 GLU A CA  1 
ATOM   6144  C  C   . GLU A 1 793 ? 191.639 187.788 141.545 1.00 54.40  ? 793 GLU A C   1 
ATOM   6145  O  O   . GLU A 1 793 ? 191.514 187.838 140.319 1.00 58.23  ? 793 GLU A O   1 
ATOM   6146  C  CB  . GLU A 1 793 ? 192.420 185.546 142.258 1.00 67.78  ? 793 GLU A CB  1 
ATOM   6147  C  CG  . GLU A 1 793 ? 193.578 184.628 142.607 1.00 72.45  ? 793 GLU A CG  1 
ATOM   6148  C  CD  . GLU A 1 793 ? 193.179 183.166 142.612 1.00 88.78  ? 793 GLU A CD  1 
ATOM   6149  O  OE1 . GLU A 1 793 ? 192.185 182.819 141.941 1.00 93.99  ? 793 GLU A OE1 1 
ATOM   6150  O  OE2 . GLU A 1 793 ? 193.860 182.365 143.286 1.00 95.66  ? 793 GLU A OE2 1 
ATOM   6151  N  N   . GLU A 1 794 ? 190.784 188.381 142.369 1.00 51.59  ? 794 GLU A N   1 
ATOM   6152  C  CA  . GLU A 1 794 ? 189.609 189.058 141.844 1.00 54.23  ? 794 GLU A CA  1 
ATOM   6153  C  C   . GLU A 1 794 ? 189.913 190.444 141.297 1.00 58.35  ? 794 GLU A C   1 
ATOM   6154  O  O   . GLU A 1 794 ? 189.009 191.084 140.753 1.00 60.30  ? 794 GLU A O   1 
ATOM   6155  C  CB  . GLU A 1 794 ? 188.545 189.164 142.933 1.00 50.14  ? 794 GLU A CB  1 
ATOM   6156  C  CG  . GLU A 1 794 ? 188.224 187.852 143.605 1.00 49.62  ? 794 GLU A CG  1 
ATOM   6157  C  CD  . GLU A 1 794 ? 187.253 188.019 144.747 1.00 52.30  ? 794 GLU A CD  1 
ATOM   6158  O  OE1 . GLU A 1 794 ? 186.784 189.153 144.967 1.00 51.68  ? 794 GLU A OE1 1 
ATOM   6159  O  OE2 . GLU A 1 794 ? 186.956 187.018 145.428 1.00 54.88  ? 794 GLU A OE2 1 
ATOM   6160  N  N   . ILE A 1 795 ? 191.150 190.924 141.436 1.00 56.37  ? 795 ILE A N   1 
ATOM   6161  C  CA  . ILE A 1 795 ? 191.446 192.312 141.086 1.00 55.39  ? 795 ILE A CA  1 
ATOM   6162  C  C   . ILE A 1 795 ? 191.228 192.599 139.605 1.00 59.03  ? 795 ILE A C   1 
ATOM   6163  O  O   . ILE A 1 795 ? 190.519 193.567 139.288 1.00 67.50  ? 795 ILE A O   1 
ATOM   6164  C  CB  . ILE A 1 795 ? 192.860 192.689 141.574 1.00 52.83  ? 795 ILE A CB  1 
ATOM   6165  C  CG1 . ILE A 1 795 ? 192.806 193.138 143.024 1.00 50.09  ? 795 ILE A CG1 1 
ATOM   6166  C  CG2 . ILE A 1 795 ? 193.450 193.786 140.724 1.00 52.50  ? 795 ILE A CG2 1 
ATOM   6167  C  CD1 . ILE A 1 795 ? 192.107 194.446 143.209 1.00 52.67  ? 795 ILE A CD1 1 
ATOM   6168  N  N   . PRO A 1 796 ? 191.783 191.829 138.660 1.00 52.80  ? 796 PRO A N   1 
ATOM   6169  C  CA  . PRO A 1 796 ? 191.467 192.096 137.248 1.00 50.00  ? 796 PRO A CA  1 
ATOM   6170  C  C   . PRO A 1 796 ? 190.021 191.842 136.902 1.00 51.94  ? 796 PRO A C   1 
ATOM   6171  O  O   . PRO A 1 796 ? 189.586 192.239 135.815 1.00 54.09  ? 796 PRO A O   1 
ATOM   6172  C  CB  . PRO A 1 796 ? 192.406 191.160 136.487 1.00 49.97  ? 796 PRO A CB  1 
ATOM   6173  C  CG  . PRO A 1 796 ? 193.503 190.910 137.420 1.00 53.39  ? 796 PRO A CG  1 
ATOM   6174  C  CD  . PRO A 1 796 ? 192.867 190.841 138.768 1.00 52.35  ? 796 PRO A CD  1 
ATOM   6175  N  N   . GLY A 1 797 ? 189.269 191.187 137.774 1.00 53.23  ? 797 GLY A N   1 
ATOM   6176  C  CA  . GLY A 1 797 ? 187.829 191.137 137.675 1.00 60.94  ? 797 GLY A CA  1 
ATOM   6177  C  C   . GLY A 1 797 ? 187.144 192.310 138.332 1.00 59.02  ? 797 GLY A C   1 
ATOM   6178  O  O   . GLY A 1 797 ? 185.921 192.282 138.505 1.00 58.34  ? 797 GLY A O   1 
ATOM   6179  N  N   . TRP A 1 798 ? 187.897 193.330 138.729 1.00 61.74  ? 798 TRP A N   1 
ATOM   6180  C  CA  . TRP A 1 798 ? 187.337 194.500 139.388 1.00 64.63  ? 798 TRP A CA  1 
ATOM   6181  C  C   . TRP A 1 798 ? 187.840 195.777 138.727 1.00 64.87  ? 798 TRP A C   1 
ATOM   6182  O  O   . TRP A 1 798 ? 187.130 196.786 138.699 1.00 67.56  ? 798 TRP A O   1 
ATOM   6183  C  CB  . TRP A 1 798 ? 187.693 194.473 140.871 1.00 61.94  ? 798 TRP A CB  1 
ATOM   6184  C  CG  . TRP A 1 798 ? 187.318 195.690 141.614 1.00 59.57  ? 798 TRP A CG  1 
ATOM   6185  C  CD1 . TRP A 1 798 ? 186.212 195.867 142.375 1.00 62.16  ? 798 TRP A CD1 1 
ATOM   6186  C  CD2 . TRP A 1 798 ? 188.067 196.900 141.697 1.00 59.40  ? 798 TRP A CD2 1 
ATOM   6187  N  NE1 . TRP A 1 798 ? 186.212 197.122 142.919 1.00 64.90  ? 798 TRP A NE1 1 
ATOM   6188  C  CE2 . TRP A 1 798 ? 187.345 197.777 142.518 1.00 63.52  ? 798 TRP A CE2 1 
ATOM   6189  C  CE3 . TRP A 1 798 ? 189.278 197.327 141.153 1.00 59.97  ? 798 TRP A CE3 1 
ATOM   6190  C  CZ2 . TRP A 1 798 ? 187.789 199.059 142.809 1.00 63.47  ? 798 TRP A CZ2 1 
ATOM   6191  C  CZ3 . TRP A 1 798 ? 189.719 198.600 141.440 1.00 67.23  ? 798 TRP A CZ3 1 
ATOM   6192  C  CH2 . TRP A 1 798 ? 188.976 199.453 142.261 1.00 65.63  ? 798 TRP A CH2 1 
ATOM   6193  N  N   . MET A 1 799 ? 189.065 195.741 138.197 1.00 61.29  ? 799 MET A N   1 
ATOM   6194  C  CA  . MET A 1 799 ? 189.596 196.898 137.487 1.00 57.86  ? 799 MET A CA  1 
ATOM   6195  C  C   . MET A 1 799 ? 188.732 197.244 136.284 1.00 66.83  ? 799 MET A C   1 
ATOM   6196  O  O   . MET A 1 799 ? 188.472 198.422 136.017 1.00 73.56  ? 799 MET A O   1 
ATOM   6197  C  CB  . MET A 1 799 ? 191.028 196.631 137.037 1.00 56.92  ? 799 MET A CB  1 
ATOM   6198  C  CG  . MET A 1 799 ? 192.098 197.118 137.983 1.00 60.31  ? 799 MET A CG  1 
ATOM   6199  S  SD  . MET A 1 799 ? 193.734 197.003 137.250 1.00 62.07  ? 799 MET A SD  1 
ATOM   6200  C  CE  . MET A 1 799 ? 194.100 198.726 136.975 1.00 68.45  ? 799 MET A CE  1 
ATOM   6201  N  N   . SER A 1 800 ? 188.280 196.232 135.543 1.00 67.44  ? 800 SER A N   1 
ATOM   6202  C  CA  . SER A 1 800 ? 187.503 196.442 134.329 1.00 66.38  ? 800 SER A CA  1 
ATOM   6203  C  C   . SER A 1 800 ? 186.018 196.147 134.514 1.00 66.80  ? 800 SER A C   1 
ATOM   6204  O  O   . SER A 1 800 ? 185.299 195.991 133.525 1.00 68.67  ? 800 SER A O   1 
ATOM   6205  C  CB  . SER A 1 800 ? 188.070 195.602 133.188 1.00 63.13  ? 800 SER A CB  1 
ATOM   6206  O  OG  . SER A 1 800 ? 187.865 194.223 133.418 1.00 62.29  ? 800 SER A OG  1 
ATOM   6207  N  N   . SER A 1 801 ? 185.538 196.060 135.752 1.00 65.08  ? 801 SER A N   1 
ATOM   6208  C  CA  . SER A 1 801 ? 184.112 195.901 136.003 1.00 64.40  ? 801 SER A CA  1 
ATOM   6209  C  C   . SER A 1 801 ? 183.517 197.109 136.712 1.00 67.26  ? 801 SER A C   1 
ATOM   6210  O  O   . SER A 1 801 ? 182.596 197.741 136.190 1.00 74.53  ? 801 SER A O   1 
ATOM   6211  C  CB  . SER A 1 801 ? 183.848 194.640 136.826 1.00 65.21  ? 801 SER A CB  1 
ATOM   6212  O  OG  . SER A 1 801 ? 182.583 194.727 137.458 1.00 67.85  ? 801 SER A OG  1 
ATOM   6213  N  N   . VAL A 1 802 ? 184.018 197.445 137.901 1.00 66.26  ? 802 VAL A N   1 
ATOM   6214  C  CA  . VAL A 1 802 ? 183.491 198.603 138.613 1.00 69.67  ? 802 VAL A CA  1 
ATOM   6215  C  C   . VAL A 1 802 ? 183.921 199.895 137.937 1.00 75.50  ? 802 VAL A C   1 
ATOM   6216  O  O   . VAL A 1 802 ? 183.218 200.909 138.023 1.00 80.65  ? 802 VAL A O   1 
ATOM   6217  C  CB  . VAL A 1 802 ? 183.904 198.561 140.091 1.00 69.26  ? 802 VAL A CB  1 
ATOM   6218  C  CG1 . VAL A 1 802 ? 183.100 199.567 140.886 1.00 70.71  ? 802 VAL A CG1 1 
ATOM   6219  C  CG2 . VAL A 1 802 ? 183.678 197.174 140.642 1.00 67.89  ? 802 VAL A CG2 1 
ATOM   6220  N  N   . LEU A 1 803 ? 185.084 199.894 137.280 1.00 74.49  ? 803 LEU A N   1 
ATOM   6221  C  CA  . LEU A 1 803 ? 185.474 200.961 136.366 1.00 78.90  ? 803 LEU A CA  1 
ATOM   6222  C  C   . LEU A 1 803 ? 185.718 202.263 137.118 1.00 79.93  ? 803 LEU A C   1 
ATOM   6223  O  O   . LEU A 1 803 ? 185.581 202.296 138.348 1.00 80.41  ? 803 LEU A O   1 
ATOM   6224  C  CB  . LEU A 1 803 ? 184.403 201.141 135.282 1.00 84.77  ? 803 LEU A CB  1 
ATOM   6225  C  CG  . LEU A 1 803 ? 184.407 200.143 134.123 1.00 84.10  ? 803 LEU A CG  1 
ATOM   6226  C  CD1 . LEU A 1 803 ? 183.089 200.199 133.366 1.00 87.66  ? 803 LEU A CD1 1 
ATOM   6227  C  CD2 . LEU A 1 803 ? 185.576 200.410 133.188 1.00 83.13  ? 803 LEU A CD2 1 
ATOM   6228  N  N   . PRO A 1 804 ? 186.148 203.343 136.431 1.00 85.08  ? 804 PRO A N   1 
ATOM   6229  C  CA  . PRO A 1 804 ? 186.157 204.664 137.073 1.00 81.70  ? 804 PRO A CA  1 
ATOM   6230  C  C   . PRO A 1 804 ? 184.830 204.991 137.731 1.00 78.09  ? 804 PRO A C   1 
ATOM   6231  O  O   . PRO A 1 804 ? 183.799 205.115 137.064 1.00 74.26  ? 804 PRO A O   1 
ATOM   6232  C  CB  . PRO A 1 804 ? 186.467 205.624 135.913 1.00 80.72  ? 804 PRO A CB  1 
ATOM   6233  C  CG  . PRO A 1 804 ? 186.558 204.762 134.666 1.00 83.26  ? 804 PRO A CG  1 
ATOM   6234  C  CD  . PRO A 1 804 ? 186.860 203.384 135.144 1.00 85.55  ? 804 PRO A CD  1 
ATOM   6235  N  N   . LEU A 1 805 ? 184.854 205.109 139.056 1.00 80.42  ? 805 LEU A N   1 
ATOM   6236  C  CA  . LEU A 1 805 ? 183.639 205.284 139.845 1.00 82.40  ? 805 LEU A CA  1 
ATOM   6237  C  C   . LEU A 1 805 ? 183.436 206.779 140.063 1.00 91.13  ? 805 LEU A C   1 
ATOM   6238  O  O   . LEU A 1 805 ? 183.979 207.393 140.983 1.00 92.00  ? 805 LEU A O   1 
ATOM   6239  C  CB  . LEU A 1 805 ? 183.743 204.511 141.155 1.00 79.01  ? 805 LEU A CB  1 
ATOM   6240  C  CG  . LEU A 1 805 ? 182.604 204.614 142.170 1.00 83.67  ? 805 LEU A CG  1 
ATOM   6241  C  CD1 . LEU A 1 805 ? 182.353 203.255 142.796 1.00 87.93  ? 805 LEU A CD1 1 
ATOM   6242  C  CD2 . LEU A 1 805 ? 182.911 205.623 143.251 1.00 84.01  ? 805 LEU A CD2 1 
ATOM   6243  N  N   . LYS A 1 806 ? 182.637 207.378 139.179 1.00 95.80  ? 806 LYS A N   1 
ATOM   6244  C  CA  . LYS A 1 806 ? 182.370 208.816 139.225 1.00 100.77 ? 806 LYS A CA  1 
ATOM   6245  C  C   . LYS A 1 806 ? 181.059 209.065 139.971 1.00 103.10 ? 806 LYS A C   1 
ATOM   6246  O  O   . LYS A 1 806 ? 180.030 209.433 139.401 1.00 106.53 ? 806 LYS A O   1 
ATOM   6247  C  CB  . LYS A 1 806 ? 182.337 209.400 137.820 1.00 101.43 ? 806 LYS A CB  1 
ATOM   6248  C  CG  . LYS A 1 806 ? 182.622 210.893 137.762 1.00 103.24 ? 806 LYS A CG  1 
ATOM   6249  C  CD  . LYS A 1 806 ? 182.762 211.375 136.328 1.00 102.28 ? 806 LYS A CD  1 
ATOM   6250  C  CE  . LYS A 1 806 ? 183.105 212.855 136.274 1.00 100.60 ? 806 LYS A CE  1 
ATOM   6251  N  NZ  . LYS A 1 806 ? 181.938 213.709 136.630 1.00 104.23 ? 806 LYS A NZ  1 
ATOM   6252  N  N   . ILE A 1 807 ? 181.114 208.857 141.281 1.00 99.28  ? 807 ILE A N   1 
ATOM   6253  C  CA  . ILE A 1 807 ? 179.945 209.055 142.124 1.00 102.22 ? 807 ILE A CA  1 
ATOM   6254  C  C   . ILE A 1 807 ? 180.024 210.416 142.804 1.00 102.25 ? 807 ILE A C   1 
ATOM   6255  O  O   . ILE A 1 807 ? 179.034 210.924 143.332 1.00 104.69 ? 807 ILE A O   1 
ATOM   6256  C  CB  . ILE A 1 807 ? 179.804 207.926 143.159 1.00 103.07 ? 807 ILE A CB  1 
ATOM   6257  C  CG1 . ILE A 1 807 ? 178.335 207.741 143.548 1.00 102.07 ? 807 ILE A CG1 1 
ATOM   6258  C  CG2 . ILE A 1 807 ? 180.648 208.219 144.389 1.00 101.03 ? 807 ILE A CG2 1 
ATOM   6259  C  CD1 . ILE A 1 807 ? 178.064 206.474 144.329 1.00 99.34  ? 807 ILE A CD1 1 
ATOM   6260  O  OXT . ILE A 1 807 ? 181.082 211.044 142.837 1.00 99.13  ? 807 ILE A OXT 1 
ATOM   6261  N  N   . GLY B 1 20  ? 179.021 217.716 304.021 1.00 129.35 ? 20  GLY B N   1 
ATOM   6262  C  CA  . GLY B 1 20  ? 180.314 217.240 304.475 1.00 130.15 ? 20  GLY B CA  1 
ATOM   6263  C  C   . GLY B 1 20  ? 181.002 216.350 303.461 1.00 130.62 ? 20  GLY B C   1 
ATOM   6264  O  O   . GLY B 1 20  ? 182.190 216.053 303.579 1.00 129.20 ? 20  GLY B O   1 
ATOM   6265  N  N   . ILE B 1 21  ? 180.248 215.953 302.434 1.00 133.17 ? 21  ILE B N   1 
ATOM   6266  C  CA  . ILE B 1 21  ? 180.705 214.941 301.489 1.00 135.80 ? 21  ILE B CA  1 
ATOM   6267  C  C   . ILE B 1 21  ? 181.928 215.368 300.698 1.00 132.56 ? 21  ILE B C   1 
ATOM   6268  O  O   . ILE B 1 21  ? 182.546 214.530 300.036 1.00 132.70 ? 21  ILE B O   1 
ATOM   6269  C  CB  . ILE B 1 21  ? 179.563 214.574 300.520 1.00 142.44 ? 21  ILE B CB  1 
ATOM   6270  C  CG1 . ILE B 1 21  ? 179.535 215.541 299.334 1.00 141.20 ? 21  ILE B CG1 1 
ATOM   6271  C  CG2 . ILE B 1 21  ? 178.227 214.590 301.244 1.00 145.15 ? 21  ILE B CG2 1 
ATOM   6272  C  CD1 . ILE B 1 21  ? 178.560 215.147 298.246 1.00 138.01 ? 21  ILE B CD1 1 
ATOM   6273  N  N   . PHE B 1 22  ? 182.296 216.647 300.753 1.00 128.78 ? 22  PHE B N   1 
ATOM   6274  C  CA  . PHE B 1 22  ? 183.427 217.125 299.969 1.00 127.94 ? 22  PHE B CA  1 
ATOM   6275  C  C   . PHE B 1 22  ? 184.720 216.451 300.403 1.00 130.54 ? 22  PHE B C   1 
ATOM   6276  O  O   . PHE B 1 22  ? 185.529 216.042 299.565 1.00 129.94 ? 22  PHE B O   1 
ATOM   6277  C  CB  . PHE B 1 22  ? 183.534 218.637 300.103 1.00 129.31 ? 22  PHE B CB  1 
ATOM   6278  C  CG  . PHE B 1 22  ? 182.935 219.166 301.369 1.00 133.37 ? 22  PHE B CG  1 
ATOM   6279  C  CD1 . PHE B 1 22  ? 183.582 218.998 302.582 1.00 134.88 ? 22  PHE B CD1 1 
ATOM   6280  C  CD2 . PHE B 1 22  ? 181.715 219.817 301.353 1.00 134.92 ? 22  PHE B CD2 1 
ATOM   6281  C  CE1 . PHE B 1 22  ? 183.031 219.480 303.747 1.00 133.32 ? 22  PHE B CE1 1 
ATOM   6282  C  CE2 . PHE B 1 22  ? 181.158 220.300 302.519 1.00 136.47 ? 22  PHE B CE2 1 
ATOM   6283  C  CZ  . PHE B 1 22  ? 181.821 220.135 303.716 1.00 133.99 ? 22  PHE B CZ  1 
ATOM   6284  N  N   . PHE B 1 23  ? 184.932 216.322 301.712 1.00 132.93 ? 23  PHE B N   1 
ATOM   6285  C  CA  . PHE B 1 23  ? 186.146 215.667 302.195 1.00 134.93 ? 23  PHE B CA  1 
ATOM   6286  C  C   . PHE B 1 23  ? 186.242 214.212 301.756 1.00 130.98 ? 23  PHE B C   1 
ATOM   6287  O  O   . PHE B 1 23  ? 187.268 213.838 301.159 1.00 128.58 ? 23  PHE B O   1 
ATOM   6288  C  CB  . PHE B 1 23  ? 186.227 215.777 303.722 1.00 137.39 ? 23  PHE B CB  1 
ATOM   6289  C  CG  . PHE B 1 23  ? 186.366 217.177 304.233 1.00 140.49 ? 23  PHE B CG  1 
ATOM   6290  C  CD1 . PHE B 1 23  ? 187.282 218.048 303.675 1.00 144.78 ? 23  PHE B CD1 1 
ATOM   6291  C  CD2 . PHE B 1 23  ? 185.582 217.618 305.286 1.00 140.60 ? 23  PHE B CD2 1 
ATOM   6292  C  CE1 . PHE B 1 23  ? 187.414 219.335 304.157 1.00 146.32 ? 23  PHE B CE1 1 
ATOM   6293  C  CE2 . PHE B 1 23  ? 185.707 218.904 305.770 1.00 144.30 ? 23  PHE B CE2 1 
ATOM   6294  C  CZ  . PHE B 1 23  ? 186.623 219.765 305.203 1.00 145.26 ? 23  PHE B CZ  1 
ATOM   6295  N  N   . PRO B 1 24  ? 185.259 213.342 302.030 1.00 131.21 ? 24  PRO B N   1 
ATOM   6296  C  CA  . PRO B 1 24  ? 185.415 211.945 301.605 1.00 133.06 ? 24  PRO B CA  1 
ATOM   6297  C  C   . PRO B 1 24  ? 185.503 211.802 300.105 1.00 132.27 ? 24  PRO B C   1 
ATOM   6298  O  O   . PRO B 1 24  ? 186.271 210.974 299.609 1.00 131.15 ? 24  PRO B O   1 
ATOM   6299  C  CB  . PRO B 1 24  ? 184.162 211.261 302.170 1.00 136.00 ? 24  PRO B CB  1 
ATOM   6300  C  CG  . PRO B 1 24  ? 183.176 212.351 302.317 1.00 135.35 ? 24  PRO B CG  1 
ATOM   6301  C  CD  . PRO B 1 24  ? 183.967 213.553 302.708 1.00 132.69 ? 24  PRO B CD  1 
ATOM   6302  N  N   . ALA B 1 25  ? 184.736 212.598 299.362 1.00 133.89 ? 25  ALA B N   1 
ATOM   6303  C  CA  . ALA B 1 25  ? 184.811 212.529 297.911 1.00 137.57 ? 25  ALA B CA  1 
ATOM   6304  C  C   . ALA B 1 25  ? 186.204 212.899 297.431 1.00 135.37 ? 25  ALA B C   1 
ATOM   6305  O  O   . ALA B 1 25  ? 186.794 212.205 296.595 1.00 136.00 ? 25  ALA B O   1 
ATOM   6306  C  CB  . ALA B 1 25  ? 183.762 213.446 297.285 1.00 139.33 ? 25  ALA B CB  1 
ATOM   6307  N  N   . LEU B 1 26  ? 186.761 213.979 297.981 1.00 133.63 ? 26  LEU B N   1 
ATOM   6308  C  CA  . LEU B 1 26  ? 188.071 214.431 297.536 1.00 137.02 ? 26  LEU B CA  1 
ATOM   6309  C  C   . LEU B 1 26  ? 189.145 213.412 297.877 1.00 135.94 ? 26  LEU B C   1 
ATOM   6310  O  O   . LEU B 1 26  ? 190.008 213.112 297.044 1.00 137.50 ? 26  LEU B O   1 
ATOM   6311  C  CB  . LEU B 1 26  ? 188.398 215.787 298.156 1.00 138.83 ? 26  LEU B CB  1 
ATOM   6312  C  CG  . LEU B 1 26  ? 187.840 217.020 297.441 1.00 140.50 ? 26  LEU B CG  1 
ATOM   6313  C  CD1 . LEU B 1 26  ? 188.462 218.285 298.007 1.00 139.31 ? 26  LEU B CD1 1 
ATOM   6314  C  CD2 . LEU B 1 26  ? 188.074 216.928 295.942 1.00 137.05 ? 26  LEU B CD2 1 
ATOM   6315  N  N   . GLU B 1 27  ? 189.101 212.853 299.086 1.00 132.53 ? 27  GLU B N   1 
ATOM   6316  C  CA  . GLU B 1 27  ? 190.096 211.847 299.434 1.00 132.88 ? 27  GLU B CA  1 
ATOM   6317  C  C   . GLU B 1 27  ? 189.907 210.581 298.612 1.00 132.29 ? 27  GLU B C   1 
ATOM   6318  O  O   . GLU B 1 27  ? 190.884 209.888 298.311 1.00 134.32 ? 27  GLU B O   1 
ATOM   6319  C  CB  . GLU B 1 27  ? 190.054 211.540 300.931 1.00 135.71 ? 27  GLU B CB  1 
ATOM   6320  C  CG  . GLU B 1 27  ? 188.748 210.973 301.433 1.00 137.69 ? 27  GLU B CG  1 
ATOM   6321  C  CD  . GLU B 1 27  ? 188.689 209.463 301.348 1.00 139.84 ? 27  GLU B CD  1 
ATOM   6322  O  OE1 . GLU B 1 27  ? 187.568 208.911 301.358 1.00 140.64 ? 27  GLU B OE1 1 
ATOM   6323  O  OE2 . GLU B 1 27  ? 189.760 208.826 301.266 1.00 140.42 ? 27  GLU B OE2 1 
ATOM   6324  N  N   . GLN B 1 28  ? 188.667 210.268 298.238 1.00 131.44 ? 28  GLN B N   1 
ATOM   6325  C  CA  . GLN B 1 28  ? 188.429 209.162 297.321 1.00 136.77 ? 28  GLN B CA  1 
ATOM   6326  C  C   . GLN B 1 28  ? 188.945 209.489 295.927 1.00 138.35 ? 28  GLN B C   1 
ATOM   6327  O  O   . GLN B 1 28  ? 189.469 208.612 295.230 1.00 142.49 ? 28  GLN B O   1 
ATOM   6328  C  CB  . GLN B 1 28  ? 186.938 208.828 297.274 1.00 138.72 ? 28  GLN B CB  1 
ATOM   6329  C  CG  . GLN B 1 28  ? 186.440 208.016 298.458 1.00 141.38 ? 28  GLN B CG  1 
ATOM   6330  C  CD  . GLN B 1 28  ? 185.004 208.342 298.822 1.00 140.46 ? 28  GLN B CD  1 
ATOM   6331  O  OE1 . GLN B 1 28  ? 184.381 209.214 298.218 1.00 140.12 ? 28  GLN B OE1 1 
ATOM   6332  N  NE2 . GLN B 1 28  ? 184.472 207.641 299.817 1.00 141.31 ? 28  GLN B NE2 1 
ATOM   6333  N  N   . ASN B 1 29  ? 188.797 210.742 295.505 1.00 136.15 ? 29  ASN B N   1 
ATOM   6334  C  CA  . ASN B 1 29  ? 189.274 211.165 294.196 1.00 134.31 ? 29  ASN B CA  1 
ATOM   6335  C  C   . ASN B 1 29  ? 190.790 211.053 294.119 1.00 135.70 ? 29  ASN B C   1 
ATOM   6336  O  O   . ASN B 1 29  ? 191.496 211.386 295.074 1.00 136.08 ? 29  ASN B O   1 
ATOM   6337  C  CB  . ASN B 1 29  ? 188.836 212.600 293.930 1.00 132.34 ? 29  ASN B CB  1 
ATOM   6338  C  CG  . ASN B 1 29  ? 188.979 212.989 292.484 1.00 131.79 ? 29  ASN B CG  1 
ATOM   6339  O  OD1 . ASN B 1 29  ? 189.384 212.183 291.654 1.00 131.05 ? 29  ASN B OD1 1 
ATOM   6340  N  ND2 . ASN B 1 29  ? 188.633 214.227 292.167 1.00 132.34 ? 29  ASN B ND2 1 
ATOM   6341  N  N   . MET B 1 30  ? 191.296 210.596 292.971 1.00 136.03 ? 30  MET B N   1 
ATOM   6342  C  CA  . MET B 1 30  ? 192.740 210.444 292.845 1.00 135.63 ? 30  MET B CA  1 
ATOM   6343  C  C   . MET B 1 30  ? 193.451 211.755 292.538 1.00 135.52 ? 30  MET B C   1 
ATOM   6344  O  O   . MET B 1 30  ? 194.680 211.757 292.419 1.00 134.07 ? 30  MET B O   1 
ATOM   6345  C  CB  . MET B 1 30  ? 193.112 209.393 291.789 1.00 133.51 ? 30  MET B CB  1 
ATOM   6346  C  CG  . MET B 1 30  ? 193.148 209.854 290.329 1.00 130.13 ? 30  MET B CG  1 
ATOM   6347  S  SD  . MET B 1 30  ? 191.835 210.953 289.778 1.00 136.31 ? 30  MET B SD  1 
ATOM   6348  C  CE  . MET B 1 30  ? 190.417 209.875 289.998 1.00 131.98 ? 30  MET B CE  1 
ATOM   6349  N  N   . MET B 1 31  ? 192.722 212.859 292.416 1.00 138.68 ? 31  MET B N   1 
ATOM   6350  C  CA  . MET B 1 31  ? 193.342 214.170 292.271 1.00 138.79 ? 31  MET B CA  1 
ATOM   6351  C  C   . MET B 1 31  ? 193.727 214.692 293.651 1.00 141.19 ? 31  MET B C   1 
ATOM   6352  O  O   . MET B 1 31  ? 192.909 214.668 294.578 1.00 143.44 ? 31  MET B O   1 
ATOM   6353  C  CB  . MET B 1 31  ? 192.384 215.130 291.573 1.00 138.64 ? 31  MET B CB  1 
ATOM   6354  C  CG  . MET B 1 31  ? 192.836 216.577 291.560 1.00 134.41 ? 31  MET B CG  1 
ATOM   6355  S  SD  . MET B 1 31  ? 191.455 217.736 291.558 1.00 145.64 ? 31  MET B SD  1 
ATOM   6356  C  CE  . MET B 1 31  ? 190.302 216.922 292.655 1.00 140.25 ? 31  MET B CE  1 
ATOM   6357  N  N   . GLY B 1 32  ? 194.968 215.154 293.795 1.00 136.95 ? 32  GLY B N   1 
ATOM   6358  C  CA  . GLY B 1 32  ? 195.428 215.611 295.098 1.00 135.77 ? 32  GLY B CA  1 
ATOM   6359  C  C   . GLY B 1 32  ? 194.696 216.868 295.536 1.00 137.07 ? 32  GLY B C   1 
ATOM   6360  O  O   . GLY B 1 32  ? 194.453 217.777 294.744 1.00 133.28 ? 32  GLY B O   1 
ATOM   6361  N  N   . ALA B 1 33  ? 194.355 216.924 296.823 1.00 141.45 ? 33  ALA B N   1 
ATOM   6362  C  CA  . ALA B 1 33  ? 193.604 218.046 297.367 1.00 141.98 ? 33  ALA B CA  1 
ATOM   6363  C  C   . ALA B 1 33  ? 194.214 218.497 298.686 1.00 143.00 ? 33  ALA B C   1 
ATOM   6364  O  O   . ALA B 1 33  ? 194.433 217.684 299.588 1.00 142.91 ? 33  ALA B O   1 
ATOM   6365  C  CB  . ALA B 1 33  ? 192.129 217.681 297.573 1.00 142.03 ? 33  ALA B CB  1 
ATOM   6366  N  N   . VAL B 1 34  ? 194.485 219.798 298.790 1.00 140.70 ? 34  VAL B N   1 
ATOM   6367  C  CA  . VAL B 1 34  ? 194.977 220.409 300.021 1.00 138.49 ? 34  VAL B CA  1 
ATOM   6368  C  C   . VAL B 1 34  ? 194.103 221.609 300.349 1.00 141.20 ? 34  VAL B C   1 
ATOM   6369  O  O   . VAL B 1 34  ? 193.859 222.462 299.490 1.00 139.12 ? 34  VAL B O   1 
ATOM   6370  C  CB  . VAL B 1 34  ? 196.455 220.840 299.908 1.00 135.54 ? 34  VAL B CB  1 
ATOM   6371  C  CG1 . VAL B 1 34  ? 196.983 221.256 301.269 1.00 138.00 ? 34  VAL B CG1 1 
ATOM   6372  C  CG2 . VAL B 1 34  ? 197.304 219.723 299.318 1.00 137.05 ? 34  VAL B CG2 1 
ATOM   6373  N  N   . LEU B 1 35  ? 193.641 221.687 301.595 1.00 147.13 ? 35  LEU B N   1 
ATOM   6374  C  CA  . LEU B 1 35  ? 192.760 222.765 302.026 1.00 148.73 ? 35  LEU B CA  1 
ATOM   6375  C  C   . LEU B 1 35  ? 193.441 223.598 303.102 1.00 149.47 ? 35  LEU B C   1 
ATOM   6376  O  O   . LEU B 1 35  ? 193.984 223.050 304.066 1.00 148.20 ? 35  LEU B O   1 
ATOM   6377  C  CB  . LEU B 1 35  ? 191.430 222.213 302.557 1.00 149.30 ? 35  LEU B CB  1 
ATOM   6378  C  CG  . LEU B 1 35  ? 190.494 223.209 303.244 1.00 151.51 ? 35  LEU B CG  1 
ATOM   6379  C  CD1 . LEU B 1 35  ? 189.877 224.164 302.233 1.00 148.88 ? 35  LEU B CD1 1 
ATOM   6380  C  CD2 . LEU B 1 35  ? 189.414 222.480 304.030 1.00 150.61 ? 35  LEU B CD2 1 
ATOM   6381  N  N   . ILE B 1 36  ? 193.413 224.924 302.939 1.00 151.74 ? 36  ILE B N   1 
ATOM   6382  C  CA  . ILE B 1 36  ? 193.999 225.835 303.915 1.00 153.17 ? 36  ILE B CA  1 
ATOM   6383  C  C   . ILE B 1 36  ? 192.979 226.902 304.292 1.00 152.50 ? 36  ILE B C   1 
ATOM   6384  O  O   . ILE B 1 36  ? 192.111 227.276 303.495 1.00 150.31 ? 36  ILE B O   1 
ATOM   6385  C  CB  . ILE B 1 36  ? 195.303 226.494 303.405 1.00 152.45 ? 36  ILE B CB  1 
ATOM   6386  C  CG1 . ILE B 1 36  ? 195.003 227.534 302.324 1.00 149.82 ? 36  ILE B CG1 1 
ATOM   6387  C  CG2 . ILE B 1 36  ? 196.277 225.443 302.889 1.00 148.22 ? 36  ILE B CG2 1 
ATOM   6388  C  CD1 . ILE B 1 36  ? 196.135 228.512 302.089 1.00 145.43 ? 36  ILE B CD1 1 
ATOM   6389  N  N   . ASN B 1 37  ? 193.094 227.390 305.526 1.00 153.23 ? 37  ASN B N   1 
ATOM   6390  C  CA  . ASN B 1 37  ? 192.201 228.402 306.070 1.00 152.65 ? 37  ASN B CA  1 
ATOM   6391  C  C   . ASN B 1 37  ? 192.790 229.796 305.856 1.00 152.40 ? 37  ASN B C   1 
ATOM   6392  O  O   . ASN B 1 37  ? 193.763 229.982 305.120 1.00 150.95 ? 37  ASN B O   1 
ATOM   6393  C  CB  . ASN B 1 37  ? 191.936 228.131 307.549 1.00 152.23 ? 37  ASN B CB  1 
ATOM   6394  C  CG  . ASN B 1 37  ? 193.173 228.320 308.409 1.00 153.04 ? 37  ASN B CG  1 
ATOM   6395  O  OD1 . ASN B 1 37  ? 194.297 228.331 307.909 1.00 152.15 ? 37  ASN B OD1 1 
ATOM   6396  N  ND2 . ASN B 1 37  ? 192.968 228.469 309.712 1.00 153.60 ? 37  ASN B ND2 1 
ATOM   6397  N  N   . GLU B 1 38  ? 192.198 230.797 306.513 1.00 152.42 ? 38  GLU B N   1 
ATOM   6398  C  CA  . GLU B 1 38  ? 192.734 232.152 306.444 1.00 152.19 ? 38  GLU B CA  1 
ATOM   6399  C  C   . GLU B 1 38  ? 194.116 232.239 307.074 1.00 150.78 ? 38  GLU B C   1 
ATOM   6400  O  O   . GLU B 1 38  ? 194.945 233.050 306.644 1.00 148.95 ? 38  GLU B O   1 
ATOM   6401  C  CB  . GLU B 1 38  ? 191.768 233.128 307.119 1.00 151.57 ? 38  GLU B CB  1 
ATOM   6402  C  CG  . GLU B 1 38  ? 191.739 233.037 308.639 1.00 152.33 ? 38  GLU B CG  1 
ATOM   6403  C  CD  . GLU B 1 38  ? 190.767 231.988 309.148 1.00 152.15 ? 38  GLU B CD  1 
ATOM   6404  O  OE1 . GLU B 1 38  ? 190.462 231.038 308.396 1.00 150.90 ? 38  GLU B OE1 1 
ATOM   6405  O  OE2 . GLU B 1 38  ? 190.314 232.110 310.305 1.00 153.91 ? 38  GLU B OE2 1 
ATOM   6406  N  N   . ASN B 1 39  ? 194.388 231.412 308.080 1.00 151.28 ? 39  ASN B N   1 
ATOM   6407  C  CA  . ASN B 1 39  ? 195.687 231.371 308.731 1.00 153.45 ? 39  ASN B CA  1 
ATOM   6408  C  C   . ASN B 1 39  ? 196.617 230.354 308.092 1.00 150.63 ? 39  ASN B C   1 
ATOM   6409  O  O   . ASN B 1 39  ? 197.646 230.012 308.684 1.00 151.18 ? 39  ASN B O   1 
ATOM   6410  C  CB  . ASN B 1 39  ? 195.522 231.064 310.222 1.00 156.11 ? 39  ASN B CB  1 
ATOM   6411  C  CG  . ASN B 1 39  ? 194.853 232.195 310.979 1.00 156.84 ? 39  ASN B CG  1 
ATOM   6412  O  OD1 . ASN B 1 39  ? 194.583 233.258 310.420 1.00 158.08 ? 39  ASN B OD1 1 
ATOM   6413  N  ND2 . ASN B 1 39  ? 194.583 231.971 312.260 1.00 155.31 ? 39  ASN B ND2 1 
ATOM   6414  N  N   . ASP B 1 40  ? 196.264 229.849 306.911 1.00 148.05 ? 40  ASP B N   1 
ATOM   6415  C  CA  . ASP B 1 40  ? 197.040 228.883 306.144 1.00 149.46 ? 40  ASP B CA  1 
ATOM   6416  C  C   . ASP B 1 40  ? 197.173 227.539 306.846 1.00 150.21 ? 40  ASP B C   1 
ATOM   6417  O  O   . ASP B 1 40  ? 197.959 226.693 306.401 1.00 150.08 ? 40  ASP B O   1 
ATOM   6418  C  CB  . ASP B 1 40  ? 198.436 229.415 305.804 1.00 148.37 ? 40  ASP B CB  1 
ATOM   6419  C  CG  . ASP B 1 40  ? 198.413 230.844 305.308 1.00 147.97 ? 40  ASP B CG  1 
ATOM   6420  O  OD1 . ASP B 1 40  ? 199.396 231.572 305.554 1.00 147.25 ? 40  ASP B OD1 1 
ATOM   6421  O  OD2 . ASP B 1 40  ? 197.411 231.242 304.680 1.00 147.93 ? 40  ASP B OD2 1 
ATOM   6422  N  N   . GLU B 1 41  ? 196.440 227.315 307.932 1.00 151.57 ? 41  GLU B N   1 
ATOM   6423  C  CA  . GLU B 1 41  ? 196.429 226.004 308.561 1.00 153.38 ? 41  GLU B CA  1 
ATOM   6424  C  C   . GLU B 1 41  ? 195.696 225.007 307.671 1.00 156.58 ? 41  GLU B C   1 
ATOM   6425  O  O   . GLU B 1 41  ? 194.738 225.350 306.975 1.00 156.84 ? 41  GLU B O   1 
ATOM   6426  C  CB  . GLU B 1 41  ? 195.770 226.071 309.937 1.00 152.41 ? 41  GLU B CB  1 
ATOM   6427  C  CG  . GLU B 1 41  ? 196.385 227.105 310.866 1.00 148.69 ? 41  GLU B CG  1 
ATOM   6428  C  CD  . GLU B 1 41  ? 195.585 227.295 312.139 1.00 143.98 ? 41  GLU B CD  1 
ATOM   6429  O  OE1 . GLU B 1 41  ? 194.385 227.628 312.044 1.00 145.18 ? 41  GLU B OE1 1 
ATOM   6430  O  OE2 . GLU B 1 41  ? 196.156 227.112 313.234 1.00 138.95 ? 41  GLU B OE2 1 
ATOM   6431  N  N   . VAL B 1 42  ? 196.160 223.764 307.694 1.00 157.80 ? 42  VAL B N   1 
ATOM   6432  C  CA  . VAL B 1 42  ? 195.650 222.726 306.805 1.00 157.76 ? 42  VAL B CA  1 
ATOM   6433  C  C   . VAL B 1 42  ? 194.580 221.923 307.533 1.00 159.30 ? 42  VAL B C   1 
ATOM   6434  O  O   . VAL B 1 42  ? 194.792 221.470 308.664 1.00 159.13 ? 42  VAL B O   1 
ATOM   6435  C  CB  . VAL B 1 42  ? 196.790 221.816 306.316 1.00 154.76 ? 42  VAL B CB  1 
ATOM   6436  C  CG1 . VAL B 1 42  ? 196.247 220.468 305.859 1.00 150.47 ? 42  VAL B CG1 1 
ATOM   6437  C  CG2 . VAL B 1 42  ? 197.566 222.493 305.196 1.00 148.63 ? 42  VAL B CG2 1 
ATOM   6438  N  N   . MET B 1 43  ? 193.423 221.758 306.892 1.00 157.82 ? 43  MET B N   1 
ATOM   6439  C  CA  . MET B 1 43  ? 192.373 220.877 307.392 1.00 155.33 ? 43  MET B CA  1 
ATOM   6440  C  C   . MET B 1 43  ? 192.251 219.577 306.614 1.00 149.91 ? 43  MET B C   1 
ATOM   6441  O  O   . MET B 1 43  ? 192.087 218.518 307.223 1.00 147.61 ? 43  MET B O   1 
ATOM   6442  C  CB  . MET B 1 43  ? 191.012 221.587 307.381 1.00 154.00 ? 43  MET B CB  1 
ATOM   6443  C  CG  . MET B 1 43  ? 190.933 222.848 308.224 1.00 157.24 ? 43  MET B CG  1 
ATOM   6444  S  SD  . MET B 1 43  ? 191.957 224.186 307.598 1.00 159.91 ? 43  MET B SD  1 
ATOM   6445  C  CE  . MET B 1 43  ? 190.817 224.945 306.445 1.00 151.46 ? 43  MET B CE  1 
ATOM   6446  N  N   . PHE B 1 44  ? 192.323 219.622 305.284 1.00 146.50 ? 44  PHE B N   1 
ATOM   6447  C  CA  . PHE B 1 44  ? 192.144 218.433 304.464 1.00 146.49 ? 44  PHE B CA  1 
ATOM   6448  C  C   . PHE B 1 44  ? 193.368 218.202 303.594 1.00 145.19 ? 44  PHE B C   1 
ATOM   6449  O  O   . PHE B 1 44  ? 193.904 219.140 302.995 1.00 144.58 ? 44  PHE B O   1 
ATOM   6450  C  CB  . PHE B 1 44  ? 190.904 218.537 303.579 1.00 146.06 ? 44  PHE B CB  1 
ATOM   6451  C  CG  . PHE B 1 44  ? 190.679 217.329 302.720 1.00 144.64 ? 44  PHE B CG  1 
ATOM   6452  C  CD1 . PHE B 1 44  ? 190.166 216.163 303.264 1.00 144.27 ? 44  PHE B CD1 1 
ATOM   6453  C  CD2 . PHE B 1 44  ? 190.992 217.351 301.374 1.00 142.14 ? 44  PHE B CD2 1 
ATOM   6454  C  CE1 . PHE B 1 44  ? 189.960 215.046 302.479 1.00 141.32 ? 44  PHE B CE1 1 
ATOM   6455  C  CE2 . PHE B 1 44  ? 190.790 216.236 300.585 1.00 141.96 ? 44  PHE B CE2 1 
ATOM   6456  C  CZ  . PHE B 1 44  ? 190.272 215.083 301.138 1.00 140.23 ? 44  PHE B CZ  1 
ATOM   6457  N  N   . PHE B 1 45  ? 193.788 216.938 303.517 1.00 145.37 ? 45  PHE B N   1 
ATOM   6458  C  CA  . PHE B 1 45  ? 194.981 216.540 302.772 1.00 143.02 ? 45  PHE B CA  1 
ATOM   6459  C  C   . PHE B 1 45  ? 194.754 215.101 302.314 1.00 139.39 ? 45  PHE B C   1 
ATOM   6460  O  O   . PHE B 1 45  ? 194.983 214.162 303.083 1.00 138.96 ? 45  PHE B O   1 
ATOM   6461  C  CB  . PHE B 1 45  ? 196.223 216.668 303.644 1.00 146.84 ? 45  PHE B CB  1 
ATOM   6462  C  CG  . PHE B 1 45  ? 197.515 216.564 302.891 1.00 146.62 ? 45  PHE B CG  1 
ATOM   6463  C  CD1 . PHE B 1 45  ? 197.981 217.626 302.137 1.00 144.80 ? 45  PHE B CD1 1 
ATOM   6464  C  CD2 . PHE B 1 45  ? 198.274 215.409 302.954 1.00 144.72 ? 45  PHE B CD2 1 
ATOM   6465  C  CE1 . PHE B 1 45  ? 199.176 217.533 301.451 1.00 142.93 ? 45  PHE B CE1 1 
ATOM   6466  C  CE2 . PHE B 1 45  ? 199.469 215.311 302.270 1.00 142.70 ? 45  PHE B CE2 1 
ATOM   6467  C  CZ  . PHE B 1 45  ? 199.920 216.374 301.519 1.00 142.05 ? 45  PHE B CZ  1 
ATOM   6468  N  N   . ASN B 1 46  ? 194.311 214.935 301.071 1.00 138.13 ? 46  ASN B N   1 
ATOM   6469  C  CA  . ASN B 1 46  ? 193.847 213.636 300.608 1.00 135.95 ? 46  ASN B CA  1 
ATOM   6470  C  C   . ASN B 1 46  ? 195.013 212.672 300.411 1.00 133.74 ? 46  ASN B C   1 
ATOM   6471  O  O   . ASN B 1 46  ? 196.161 213.093 300.248 1.00 133.00 ? 46  ASN B O   1 
ATOM   6472  C  CB  . ASN B 1 46  ? 193.053 213.794 299.313 1.00 135.63 ? 46  ASN B CB  1 
ATOM   6473  C  CG  . ASN B 1 46  ? 193.932 213.978 298.094 1.00 135.74 ? 46  ASN B CG  1 
ATOM   6474  O  OD1 . ASN B 1 46  ? 195.025 214.530 298.172 1.00 134.07 ? 46  ASN B OD1 1 
ATOM   6475  N  ND2 . ASN B 1 46  ? 193.441 213.524 296.949 1.00 138.17 ? 46  ASN B ND2 1 
ATOM   6476  N  N   . PRO B 1 47  ? 194.744 211.361 300.436 1.00 134.04 ? 47  PRO B N   1 
ATOM   6477  C  CA  . PRO B 1 47  ? 195.839 210.389 300.288 1.00 133.51 ? 47  PRO B CA  1 
ATOM   6478  C  C   . PRO B 1 47  ? 196.610 210.540 298.993 1.00 128.48 ? 47  PRO B C   1 
ATOM   6479  O  O   . PRO B 1 47  ? 197.792 210.182 298.942 1.00 128.12 ? 47  PRO B O   1 
ATOM   6480  C  CB  . PRO B 1 47  ? 195.119 209.036 300.362 1.00 129.87 ? 47  PRO B CB  1 
ATOM   6481  C  CG  . PRO B 1 47  ? 193.883 209.313 301.138 1.00 129.96 ? 47  PRO B CG  1 
ATOM   6482  C  CD  . PRO B 1 47  ? 193.466 210.702 300.757 1.00 134.18 ? 47  PRO B CD  1 
ATOM   6483  N  N   . ALA B 1 48  ? 195.980 211.050 297.937 1.00 124.80 ? 48  ALA B N   1 
ATOM   6484  C  CA  . ALA B 1 48  ? 196.742 211.370 296.739 1.00 123.62 ? 48  ALA B CA  1 
ATOM   6485  C  C   . ALA B 1 48  ? 197.800 212.413 297.052 1.00 122.28 ? 48  ALA B C   1 
ATOM   6486  O  O   . ALA B 1 48  ? 198.960 212.273 296.656 1.00 121.92 ? 48  ALA B O   1 
ATOM   6487  C  CB  . ALA B 1 48  ? 195.812 211.850 295.627 1.00 129.93 ? 48  ALA B CB  1 
ATOM   6488  N  N   . ALA B 1 49  ? 197.423 213.457 297.792 1.00 123.88 ? 49  ALA B N   1 
ATOM   6489  C  CA  . ALA B 1 49  ? 198.420 214.428 298.224 1.00 127.27 ? 49  ALA B CA  1 
ATOM   6490  C  C   . ALA B 1 49  ? 199.426 213.792 299.166 1.00 128.84 ? 49  ALA B C   1 
ATOM   6491  O  O   . ALA B 1 49  ? 200.602 214.175 299.172 1.00 129.45 ? 49  ALA B O   1 
ATOM   6492  C  CB  . ALA B 1 49  ? 197.747 215.624 298.893 1.00 130.03 ? 49  ALA B CB  1 
ATOM   6493  N  N   . GLU B 1 50  ? 198.988 212.811 299.956 1.00 131.87 ? 50  GLU B N   1 
ATOM   6494  C  CA  . GLU B 1 50  ? 199.906 212.127 300.859 1.00 137.55 ? 50  GLU B CA  1 
ATOM   6495  C  C   . GLU B 1 50  ? 201.002 211.411 300.082 1.00 136.56 ? 50  GLU B C   1 
ATOM   6496  O  O   . GLU B 1 50  ? 202.184 211.499 300.431 1.00 139.51 ? 50  GLU B O   1 
ATOM   6497  C  CB  . GLU B 1 50  ? 199.138 211.145 301.744 1.00 140.49 ? 50  GLU B CB  1 
ATOM   6498  C  CG  . GLU B 1 50  ? 198.329 211.804 302.849 1.00 139.81 ? 50  GLU B CG  1 
ATOM   6499  C  CD  . GLU B 1 50  ? 197.848 210.811 303.889 1.00 141.85 ? 50  GLU B CD  1 
ATOM   6500  O  OE1 . GLU B 1 50  ? 197.187 209.823 303.508 1.00 138.73 ? 50  GLU B OE1 1 
ATOM   6501  O  OE2 . GLU B 1 50  ? 198.132 211.019 305.087 1.00 146.81 ? 50  GLU B OE2 1 
ATOM   6502  N  N   . LYS B 1 51  ? 200.630 210.699 299.017 1.00 131.11 ? 51  LYS B N   1 
ATOM   6503  C  CA  . LYS B 1 51  ? 201.637 210.021 298.213 1.00 130.01 ? 51  LYS B CA  1 
ATOM   6504  C  C   . LYS B 1 51  ? 202.383 210.978 297.298 1.00 127.08 ? 51  LYS B C   1 
ATOM   6505  O  O   . LYS B 1 51  ? 203.492 210.658 296.859 1.00 127.41 ? 51  LYS B O   1 
ATOM   6506  C  CB  . LYS B 1 51  ? 201.008 208.894 297.389 1.00 127.19 ? 51  LYS B CB  1 
ATOM   6507  C  CG  . LYS B 1 51  ? 199.768 209.271 296.602 1.00 125.70 ? 51  LYS B CG  1 
ATOM   6508  C  CD  . LYS B 1 51  ? 199.209 208.056 295.878 1.00 124.94 ? 51  LYS B CD  1 
ATOM   6509  C  CE  . LYS B 1 51  ? 197.702 208.138 295.723 1.00 126.14 ? 51  LYS B CE  1 
ATOM   6510  N  NZ  . LYS B 1 51  ? 197.007 207.982 297.031 1.00 127.55 ? 51  LYS B NZ  1 
ATOM   6511  N  N   . LEU B 1 52  ? 201.808 212.142 297.008 1.00 124.85 ? 52  LEU B N   1 
ATOM   6512  C  CA  . LEU B 1 52  ? 202.521 213.128 296.208 1.00 127.60 ? 52  LEU B CA  1 
ATOM   6513  C  C   . LEU B 1 52  ? 203.647 213.764 297.008 1.00 127.23 ? 52  LEU B C   1 
ATOM   6514  O  O   . LEU B 1 52  ? 204.764 213.930 296.506 1.00 124.28 ? 52  LEU B O   1 
ATOM   6515  C  CB  . LEU B 1 52  ? 201.546 214.189 295.701 1.00 131.29 ? 52  LEU B CB  1 
ATOM   6516  C  CG  . LEU B 1 52  ? 200.900 213.881 294.349 1.00 128.39 ? 52  LEU B CG  1 
ATOM   6517  C  CD1 . LEU B 1 52  ? 199.499 214.469 294.266 1.00 124.26 ? 52  LEU B CD1 1 
ATOM   6518  C  CD2 . LEU B 1 52  ? 201.771 214.394 293.212 1.00 121.96 ? 52  LEU B CD2 1 
ATOM   6519  N  N   . TRP B 1 53  ? 203.374 214.123 298.258 1.00 130.71 ? 53  TRP B N   1 
ATOM   6520  C  CA  . TRP B 1 53  ? 204.374 214.794 299.078 1.00 133.30 ? 53  TRP B CA  1 
ATOM   6521  C  C   . TRP B 1 53  ? 205.229 213.814 299.872 1.00 136.32 ? 53  TRP B C   1 
ATOM   6522  O  O   . TRP B 1 53  ? 206.444 214.008 299.987 1.00 136.31 ? 53  TRP B O   1 
ATOM   6523  C  CB  . TRP B 1 53  ? 203.688 215.773 300.028 1.00 134.06 ? 53  TRP B CB  1 
ATOM   6524  C  CG  . TRP B 1 53  ? 203.524 217.134 299.449 1.00 133.93 ? 53  TRP B CG  1 
ATOM   6525  C  CD1 . TRP B 1 53  ? 204.441 218.139 299.447 1.00 136.04 ? 53  TRP B CD1 1 
ATOM   6526  C  CD2 . TRP B 1 53  ? 202.368 217.641 298.775 1.00 134.89 ? 53  TRP B CD2 1 
ATOM   6527  N  NE1 . TRP B 1 53  ? 203.926 219.247 298.821 1.00 138.01 ? 53  TRP B NE1 1 
ATOM   6528  C  CE2 . TRP B 1 53  ? 202.654 218.966 298.398 1.00 137.57 ? 53  TRP B CE2 1 
ATOM   6529  C  CE3 . TRP B 1 53  ? 201.118 217.105 298.457 1.00 133.61 ? 53  TRP B CE3 1 
ATOM   6530  C  CZ2 . TRP B 1 53  ? 201.737 219.762 297.720 1.00 136.44 ? 53  TRP B CZ2 1 
ATOM   6531  C  CZ3 . TRP B 1 53  ? 200.210 217.896 297.787 1.00 134.92 ? 53  TRP B CZ3 1 
ATOM   6532  C  CH2 . TRP B 1 53  ? 200.523 219.211 297.425 1.00 136.76 ? 53  TRP B CH2 1 
ATOM   6533  N  N   . GLY B 1 54  ? 204.619 212.763 300.419 1.00 137.97 ? 54  GLY B N   1 
ATOM   6534  C  CA  . GLY B 1 54  ? 205.305 211.788 301.234 1.00 139.16 ? 54  GLY B CA  1 
ATOM   6535  C  C   . GLY B 1 54  ? 205.073 211.934 302.724 1.00 141.78 ? 54  GLY B C   1 
ATOM   6536  O  O   . GLY B 1 54  ? 205.330 210.985 303.473 1.00 140.35 ? 54  GLY B O   1 
ATOM   6537  N  N   . TYR B 1 55  ? 204.586 213.088 303.169 1.00 143.58 ? 55  TYR B N   1 
ATOM   6538  C  CA  . TYR B 1 55  ? 204.316 213.311 304.579 1.00 143.61 ? 55  TYR B CA  1 
ATOM   6539  C  C   . TYR B 1 55  ? 202.986 212.672 304.975 1.00 144.72 ? 55  TYR B C   1 
ATOM   6540  O  O   . TYR B 1 55  ? 202.248 212.134 304.145 1.00 143.64 ? 55  TYR B O   1 
ATOM   6541  C  CB  . TYR B 1 55  ? 204.300 214.806 304.893 1.00 143.73 ? 55  TYR B CB  1 
ATOM   6542  C  CG  . TYR B 1 55  ? 205.600 215.514 304.584 1.00 141.90 ? 55  TYR B CG  1 
ATOM   6543  C  CD1 . TYR B 1 55  ? 206.759 215.224 305.290 1.00 137.74 ? 55  TYR B CD1 1 
ATOM   6544  C  CD2 . TYR B 1 55  ? 205.665 216.480 303.590 1.00 141.90 ? 55  TYR B CD2 1 
ATOM   6545  C  CE1 . TYR B 1 55  ? 207.945 215.872 305.010 1.00 136.01 ? 55  TYR B CE1 1 
ATOM   6546  C  CE2 . TYR B 1 55  ? 206.844 217.132 303.305 1.00 140.89 ? 55  TYR B CE2 1 
ATOM   6547  C  CZ  . TYR B 1 55  ? 207.980 216.825 304.016 1.00 138.48 ? 55  TYR B CZ  1 
ATOM   6548  O  OH  . TYR B 1 55  ? 209.158 217.475 303.731 1.00 140.06 ? 55  TYR B OH  1 
ATOM   6549  N  N   . LYS B 1 56  ? 202.683 212.736 306.267 1.00 146.25 ? 56  LYS B N   1 
ATOM   6550  C  CA  . LYS B 1 56  ? 201.450 212.189 306.808 1.00 147.80 ? 56  LYS B CA  1 
ATOM   6551  C  C   . LYS B 1 56  ? 200.598 213.305 307.393 1.00 149.10 ? 56  LYS B C   1 
ATOM   6552  O  O   . LYS B 1 56  ? 201.116 214.290 307.928 1.00 146.65 ? 56  LYS B O   1 
ATOM   6553  C  CB  . LYS B 1 56  ? 201.735 211.125 307.873 1.00 143.90 ? 56  LYS B CB  1 
ATOM   6554  C  CG  . LYS B 1 56  ? 202.594 209.979 307.368 1.00 137.39 ? 56  LYS B CG  1 
ATOM   6555  C  CD  . LYS B 1 56  ? 202.011 209.383 306.097 1.00 131.17 ? 56  LYS B CD  1 
ATOM   6556  C  CE  . LYS B 1 56  ? 202.942 208.346 305.492 1.00 123.97 ? 56  LYS B CE  1 
ATOM   6557  N  NZ  . LYS B 1 56  ? 202.415 207.813 304.206 1.00 121.92 ? 56  LYS B NZ  1 
ATOM   6558  N  N   . ARG B 1 57  ? 199.278 213.125 307.301 1.00 149.92 ? 57  ARG B N   1 
ATOM   6559  C  CA  . ARG B 1 57  ? 198.349 214.180 307.693 1.00 150.52 ? 57  ARG B CA  1 
ATOM   6560  C  C   . ARG B 1 57  ? 198.544 214.595 309.143 1.00 150.07 ? 57  ARG B C   1 
ATOM   6561  O  O   . ARG B 1 57  ? 198.226 215.732 309.510 1.00 148.44 ? 57  ARG B O   1 
ATOM   6562  C  CB  . ARG B 1 57  ? 196.909 213.722 307.463 1.00 149.17 ? 57  ARG B CB  1 
ATOM   6563  C  CG  . ARG B 1 57  ? 196.575 212.384 308.097 1.00 150.11 ? 57  ARG B CG  1 
ATOM   6564  C  CD  . ARG B 1 57  ? 195.075 212.144 308.116 1.00 150.75 ? 57  ARG B CD  1 
ATOM   6565  N  NE  . ARG B 1 57  ? 194.460 212.433 306.826 1.00 153.66 ? 57  ARG B NE  1 
ATOM   6566  C  CZ  . ARG B 1 57  ? 193.253 212.021 306.463 1.00 155.31 ? 57  ARG B CZ  1 
ATOM   6567  N  NH1 . ARG B 1 57  ? 192.498 211.297 307.272 1.00 152.06 ? 57  ARG B NH1 1 
ATOM   6568  N  NH2 . ARG B 1 57  ? 192.792 212.345 305.259 1.00 154.26 ? 57  ARG B NH2 1 
ATOM   6569  N  N   . GLU B 1 58  ? 199.074 213.698 309.977 1.00 152.95 ? 58  GLU B N   1 
ATOM   6570  C  CA  . GLU B 1 58  ? 199.372 214.064 311.356 1.00 156.13 ? 58  GLU B CA  1 
ATOM   6571  C  C   . GLU B 1 58  ? 200.506 215.077 311.427 1.00 156.41 ? 58  GLU B C   1 
ATOM   6572  O  O   . GLU B 1 58  ? 200.723 215.693 312.477 1.00 158.59 ? 58  GLU B O   1 
ATOM   6573  C  CB  . GLU B 1 58  ? 199.723 212.817 312.167 1.00 158.12 ? 58  GLU B CB  1 
ATOM   6574  C  CG  . GLU B 1 58  ? 198.597 211.799 312.270 1.00 160.32 ? 58  GLU B CG  1 
ATOM   6575  C  CD  . GLU B 1 58  ? 198.661 210.746 311.180 1.00 159.99 ? 58  GLU B CD  1 
ATOM   6576  O  OE1 . GLU B 1 58  ? 199.287 211.009 310.131 1.00 157.24 ? 58  GLU B OE1 1 
ATOM   6577  O  OE2 . GLU B 1 58  ? 198.087 209.654 311.373 1.00 160.78 ? 58  GLU B OE2 1 
ATOM   6578  N  N   . GLU B 1 59  ? 201.237 215.264 310.327 1.00 153.22 ? 59  GLU B N   1 
ATOM   6579  C  CA  . GLU B 1 59  ? 202.366 216.179 310.296 1.00 155.30 ? 59  GLU B CA  1 
ATOM   6580  C  C   . GLU B 1 59  ? 202.246 217.258 309.231 1.00 151.25 ? 59  GLU B C   1 
ATOM   6581  O  O   . GLU B 1 59  ? 202.980 218.250 309.300 1.00 151.05 ? 59  GLU B O   1 
ATOM   6582  C  CB  . GLU B 1 59  ? 203.671 215.399 310.077 1.00 156.00 ? 59  GLU B CB  1 
ATOM   6583  C  CG  . GLU B 1 59  ? 204.912 216.077 310.644 1.00 158.55 ? 59  GLU B CG  1 
ATOM   6584  C  CD  . GLU B 1 59  ? 205.106 215.806 312.124 1.00 157.48 ? 59  GLU B CD  1 
ATOM   6585  O  OE1 . GLU B 1 59  ? 204.227 215.164 312.737 1.00 155.02 ? 59  GLU B OE1 1 
ATOM   6586  O  OE2 . GLU B 1 59  ? 206.141 216.235 312.676 1.00 159.70 ? 59  GLU B OE2 1 
ATOM   6587  N  N   . VAL B 1 60  ? 201.346 217.105 308.257 1.00 149.36 ? 60  VAL B N   1 
ATOM   6588  C  CA  . VAL B 1 60  ? 201.227 218.115 307.209 1.00 151.45 ? 60  VAL B CA  1 
ATOM   6589  C  C   . VAL B 1 60  ? 200.709 219.424 307.787 1.00 151.80 ? 60  VAL B C   1 
ATOM   6590  O  O   . VAL B 1 60  ? 200.863 220.490 307.179 1.00 154.66 ? 60  VAL B O   1 
ATOM   6591  C  CB  . VAL B 1 60  ? 200.331 217.613 306.061 1.00 151.85 ? 60  VAL B CB  1 
ATOM   6592  C  CG1 . VAL B 1 60  ? 200.813 216.266 305.553 1.00 149.46 ? 60  VAL B CG1 1 
ATOM   6593  C  CG2 . VAL B 1 60  ? 198.876 217.545 306.504 1.00 151.34 ? 60  VAL B CG2 1 
ATOM   6594  N  N   . ILE B 1 61  ? 200.081 219.369 308.962 1.00 151.74 ? 61  ILE B N   1 
ATOM   6595  C  CA  . ILE B 1 61  ? 199.601 220.594 309.595 1.00 154.35 ? 61  ILE B CA  1 
ATOM   6596  C  C   . ILE B 1 61  ? 200.785 221.446 310.034 1.00 155.43 ? 61  ILE B C   1 
ATOM   6597  O  O   . ILE B 1 61  ? 201.018 222.539 309.504 1.00 155.20 ? 61  ILE B O   1 
ATOM   6598  C  CB  . ILE B 1 61  ? 198.676 220.264 310.780 1.00 153.20 ? 61  ILE B CB  1 
ATOM   6599  C  CG1 . ILE B 1 61  ? 197.847 219.012 310.484 1.00 150.03 ? 61  ILE B CG1 1 
ATOM   6600  C  CG2 . ILE B 1 61  ? 197.765 221.440 311.084 1.00 153.42 ? 61  ILE B CG2 1 
ATOM   6601  C  CD1 . ILE B 1 61  ? 196.858 219.176 309.358 1.00 145.90 ? 61  ILE B CD1 1 
ATOM   6602  N  N   . GLY B 1 62  ? 201.564 220.934 310.985 1.00 155.56 ? 62  GLY B N   1 
ATOM   6603  C  CA  . GLY B 1 62  ? 202.800 221.582 311.393 1.00 157.19 ? 62  GLY B CA  1 
ATOM   6604  C  C   . GLY B 1 62  ? 202.607 223.043 311.731 1.00 162.77 ? 62  GLY B C   1 
ATOM   6605  O  O   . GLY B 1 62  ? 201.708 223.420 312.494 1.00 162.07 ? 62  GLY B O   1 
ATOM   6606  N  N   . ASN B 1 63  ? 203.462 223.882 311.156 1.00 167.77 ? 63  ASN B N   1 
ATOM   6607  C  CA  . ASN B 1 63  ? 203.343 225.333 311.241 1.00 167.37 ? 63  ASN B CA  1 
ATOM   6608  C  C   . ASN B 1 63  ? 203.081 225.851 309.832 1.00 160.92 ? 63  ASN B C   1 
ATOM   6609  O  O   . ASN B 1 63  ? 203.959 225.771 308.965 1.00 157.92 ? 63  ASN B O   1 
ATOM   6610  C  CB  . ASN B 1 63  ? 204.604 225.954 311.837 1.00 166.74 ? 63  ASN B CB  1 
ATOM   6611  C  CG  . ASN B 1 63  ? 204.952 225.375 313.195 1.00 163.91 ? 63  ASN B CG  1 
ATOM   6612  O  OD1 . ASN B 1 63  ? 204.307 225.680 314.197 1.00 161.10 ? 63  ASN B OD1 1 
ATOM   6613  N  ND2 . ASN B 1 63  ? 205.979 224.533 313.233 1.00 165.06 ? 63  ASN B ND2 1 
ATOM   6614  N  N   . ASN B 1 64  ? 201.874 226.372 309.609 1.00 157.80 ? 64  ASN B N   1 
ATOM   6615  C  CA  . ASN B 1 64  ? 201.470 226.899 308.310 1.00 151.69 ? 64  ASN B CA  1 
ATOM   6616  C  C   . ASN B 1 64  ? 201.598 225.845 307.218 1.00 148.20 ? 64  ASN B C   1 
ATOM   6617  O  O   . ASN B 1 64  ? 201.024 224.757 307.327 1.00 146.44 ? 64  ASN B O   1 
ATOM   6618  C  CB  . ASN B 1 64  ? 202.295 228.139 307.957 1.00 149.71 ? 64  ASN B CB  1 
ATOM   6619  C  CG  . ASN B 1 64  ? 201.623 229.006 306.919 1.00 146.27 ? 64  ASN B CG  1 
ATOM   6620  O  OD1 . ASN B 1 64  ? 201.433 228.588 305.781 1.00 145.20 ? 64  ASN B OD1 1 
ATOM   6621  N  ND2 . ASN B 1 64  ? 201.256 230.220 307.308 1.00 144.88 ? 64  ASN B ND2 1 
ATOM   6622  N  N   . ILE B 1 65  ? 202.357 226.155 306.170 1.00 146.83 ? 65  ILE B N   1 
ATOM   6623  C  CA  . ILE B 1 65  ? 202.477 225.282 305.009 1.00 146.24 ? 65  ILE B CA  1 
ATOM   6624  C  C   . ILE B 1 65  ? 203.956 225.013 304.756 1.00 144.98 ? 65  ILE B C   1 
ATOM   6625  O  O   . ILE B 1 65  ? 204.373 224.720 303.630 1.00 146.01 ? 65  ILE B O   1 
ATOM   6626  C  CB  . ILE B 1 65  ? 201.772 225.910 303.789 1.00 147.59 ? 65  ILE B CB  1 
ATOM   6627  C  CG1 . ILE B 1 65  ? 201.464 224.852 302.725 1.00 148.06 ? 65  ILE B CG1 1 
ATOM   6628  C  CG2 . ILE B 1 65  ? 202.564 227.096 303.230 1.00 144.75 ? 65  ILE B CG2 1 
ATOM   6629  C  CD1 . ILE B 1 65  ? 200.617 223.714 303.241 1.00 146.38 ? 65  ILE B CD1 1 
ATOM   6630  N  N   . ASP B 1 66  ? 204.750 225.072 305.825 1.00 145.92 ? 66  ASP B N   1 
ATOM   6631  C  CA  . ASP B 1 66  ? 206.201 224.959 305.704 1.00 147.55 ? 66  ASP B CA  1 
ATOM   6632  C  C   . ASP B 1 66  ? 206.618 223.635 305.072 1.00 145.50 ? 66  ASP B C   1 
ATOM   6633  O  O   . ASP B 1 66  ? 207.510 223.600 304.217 1.00 146.70 ? 66  ASP B O   1 
ATOM   6634  C  CB  . ASP B 1 66  ? 206.831 225.117 307.091 1.00 150.89 ? 66  ASP B CB  1 
ATOM   6635  C  CG  . ASP B 1 66  ? 208.311 224.781 307.115 1.00 151.49 ? 66  ASP B CG  1 
ATOM   6636  O  OD1 . ASP B 1 66  ? 209.010 225.058 306.123 1.00 153.26 ? 66  ASP B OD1 1 
ATOM   6637  O  OD2 . ASP B 1 66  ? 208.776 224.235 308.137 1.00 149.71 ? 66  ASP B OD2 1 
ATOM   6638  N  N   . MET B 1 67  ? 205.987 222.538 305.480 1.00 142.61 ? 67  MET B N   1 
ATOM   6639  C  CA  . MET B 1 67  ? 206.438 221.220 305.048 1.00 143.89 ? 67  MET B CA  1 
ATOM   6640  C  C   . MET B 1 67  ? 206.241 221.013 303.550 1.00 147.99 ? 67  MET B C   1 
ATOM   6641  O  O   . MET B 1 67  ? 207.117 220.457 302.878 1.00 145.45 ? 67  MET B O   1 
ATOM   6642  C  CB  . MET B 1 67  ? 205.707 220.145 305.849 1.00 144.11 ? 67  MET B CB  1 
ATOM   6643  C  CG  . MET B 1 67  ? 204.192 220.268 305.800 1.00 149.05 ? 67  MET B CG  1 
ATOM   6644  S  SD  . MET B 1 67  ? 203.609 221.871 306.392 1.00 152.89 ? 67  MET B SD  1 
ATOM   6645  C  CE  . MET B 1 67  ? 204.170 221.835 308.090 1.00 153.00 ? 67  MET B CE  1 
ATOM   6646  N  N   . LEU B 1 68  ? 205.102 221.449 303.008 1.00 152.81 ? 68  LEU B N   1 
ATOM   6647  C  CA  . LEU B 1 68  ? 204.763 221.131 301.623 1.00 150.25 ? 68  LEU B CA  1 
ATOM   6648  C  C   . LEU B 1 68  ? 205.595 221.935 300.628 1.00 147.80 ? 68  LEU B C   1 
ATOM   6649  O  O   . LEU B 1 68  ? 206.120 221.378 299.657 1.00 145.45 ? 68  LEU B O   1 
ATOM   6650  C  CB  . LEU B 1 68  ? 203.271 221.367 301.380 1.00 146.24 ? 68  LEU B CB  1 
ATOM   6651  C  CG  . LEU B 1 68  ? 202.290 220.531 302.203 1.00 142.35 ? 68  LEU B CG  1 
ATOM   6652  C  CD1 . LEU B 1 68  ? 200.915 220.552 301.557 1.00 137.61 ? 68  LEU B CD1 1 
ATOM   6653  C  CD2 . LEU B 1 68  ? 202.786 219.102 302.370 1.00 139.13 ? 68  LEU B CD2 1 
ATOM   6654  N  N   . ILE B 1 69  ? 205.721 223.238 300.849 1.00 148.49 ? 69  ILE B N   1 
ATOM   6655  C  CA  . ILE B 1 69  ? 206.418 224.099 299.885 1.00 146.04 ? 69  ILE B CA  1 
ATOM   6656  C  C   . ILE B 1 69  ? 207.903 223.758 299.893 1.00 149.78 ? 69  ILE B C   1 
ATOM   6657  O  O   . ILE B 1 69  ? 208.442 223.394 300.953 1.00 152.44 ? 69  ILE B O   1 
ATOM   6658  C  CB  . ILE B 1 69  ? 206.191 225.572 300.230 1.00 144.67 ? 69  ILE B CB  1 
ATOM   6659  C  CG1 . ILE B 1 69  ? 204.740 225.810 300.647 1.00 141.44 ? 69  ILE B CG1 1 
ATOM   6660  C  CG2 . ILE B 1 69  ? 206.534 226.466 299.053 1.00 136.75 ? 69  ILE B CG2 1 
ATOM   6661  C  CD1 . ILE B 1 69  ? 203.733 225.502 299.578 1.00 132.48 ? 69  ILE B CD1 1 
ATOM   6662  N  N   . PRO B 1 70  ? 208.595 223.829 298.757 1.00 148.78 ? 70  PRO B N   1 
ATOM   6663  C  CA  . PRO B 1 70  ? 210.057 223.715 298.786 1.00 147.09 ? 70  PRO B CA  1 
ATOM   6664  C  C   . PRO B 1 70  ? 210.666 224.804 299.657 1.00 144.16 ? 70  PRO B C   1 
ATOM   6665  O  O   . PRO B 1 70  ? 210.173 225.932 299.712 1.00 143.32 ? 70  PRO B O   1 
ATOM   6666  C  CB  . PRO B 1 70  ? 210.453 223.876 297.316 1.00 146.46 ? 70  PRO B CB  1 
ATOM   6667  C  CG  . PRO B 1 70  ? 209.266 223.394 296.561 1.00 143.75 ? 70  PRO B CG  1 
ATOM   6668  C  CD  . PRO B 1 70  ? 208.062 223.762 297.387 1.00 143.86 ? 70  PRO B CD  1 
ATOM   6669  N  N   . ARG B 1 71  ? 211.751 224.449 300.347 1.00 140.97 ? 71  ARG B N   1 
ATOM   6670  C  CA  . ARG B 1 71  ? 212.320 225.341 301.349 1.00 141.46 ? 71  ARG B CA  1 
ATOM   6671  C  C   . ARG B 1 71  ? 212.860 226.633 300.754 1.00 138.02 ? 71  ARG B C   1 
ATOM   6672  O  O   . ARG B 1 71  ? 212.842 227.664 301.432 1.00 137.14 ? 71  ARG B O   1 
ATOM   6673  C  CB  . ARG B 1 71  ? 213.424 224.617 302.118 1.00 145.43 ? 71  ARG B CB  1 
ATOM   6674  C  CG  . ARG B 1 71  ? 212.944 223.368 302.841 1.00 146.90 ? 71  ARG B CG  1 
ATOM   6675  C  CD  . ARG B 1 71  ? 214.078 222.382 303.064 1.00 153.38 ? 71  ARG B CD  1 
ATOM   6676  N  NE  . ARG B 1 71  ? 215.030 222.857 304.061 1.00 159.54 ? 71  ARG B NE  1 
ATOM   6677  C  CZ  . ARG B 1 71  ? 216.240 222.348 304.244 1.00 160.08 ? 71  ARG B CZ  1 
ATOM   6678  N  NH1 . ARG B 1 71  ? 216.683 221.338 303.513 1.00 158.01 ? 71  ARG B NH1 1 
ATOM   6679  N  NH2 . ARG B 1 71  ? 217.026 222.865 305.184 1.00 160.34 ? 71  ARG B NH2 1 
ATOM   6680  N  N   . ASP B 1 72  ? 213.334 226.607 299.510 1.00 134.96 ? 72  ASP B N   1 
ATOM   6681  C  CA  . ASP B 1 72  ? 213.917 227.809 298.925 1.00 133.44 ? 72  ASP B CA  1 
ATOM   6682  C  C   . ASP B 1 72  ? 212.857 228.854 298.595 1.00 135.73 ? 72  ASP B C   1 
ATOM   6683  O  O   . ASP B 1 72  ? 213.031 230.037 298.906 1.00 132.76 ? 72  ASP B O   1 
ATOM   6684  C  CB  . ASP B 1 72  ? 214.715 227.445 297.674 1.00 132.17 ? 72  ASP B CB  1 
ATOM   6685  C  CG  . ASP B 1 72  ? 214.024 226.396 296.835 1.00 129.33 ? 72  ASP B CG  1 
ATOM   6686  O  OD1 . ASP B 1 72  ? 212.962 225.902 297.265 1.00 131.50 ? 72  ASP B OD1 1 
ATOM   6687  O  OD2 . ASP B 1 72  ? 214.541 226.064 295.749 1.00 121.85 ? 72  ASP B OD2 1 
ATOM   6688  N  N   . LEU B 1 73  ? 211.754 228.438 297.974 1.00 138.03 ? 73  LEU B N   1 
ATOM   6689  C  CA  . LEU B 1 73  ? 210.710 229.374 297.575 1.00 136.82 ? 73  LEU B CA  1 
ATOM   6690  C  C   . LEU B 1 73  ? 209.837 229.811 298.743 1.00 134.19 ? 73  LEU B C   1 
ATOM   6691  O  O   . LEU B 1 73  ? 209.061 230.762 298.590 1.00 132.43 ? 73  LEU B O   1 
ATOM   6692  C  CB  . LEU B 1 73  ? 209.845 228.741 296.484 1.00 135.42 ? 73  LEU B CB  1 
ATOM   6693  C  CG  . LEU B 1 73  ? 208.874 229.637 295.716 1.00 135.21 ? 73  LEU B CG  1 
ATOM   6694  C  CD1 . LEU B 1 73  ? 209.618 230.537 294.742 1.00 132.01 ? 73  LEU B CD1 1 
ATOM   6695  C  CD2 . LEU B 1 73  ? 207.843 228.788 294.999 1.00 132.30 ? 73  LEU B CD2 1 
ATOM   6696  N  N   . ARG B 1 74  ? 209.972 229.158 299.898 1.00 132.65 ? 74  ARG B N   1 
ATOM   6697  C  CA  . ARG B 1 74  ? 209.149 229.444 301.072 1.00 130.05 ? 74  ARG B CA  1 
ATOM   6698  C  C   . ARG B 1 74  ? 208.890 230.927 301.303 1.00 127.33 ? 74  ARG B C   1 
ATOM   6699  O  O   . ARG B 1 74  ? 207.714 231.324 301.308 1.00 124.29 ? 74  ARG B O   1 
ATOM   6700  C  CB  . ARG B 1 74  ? 209.812 228.814 302.303 1.00 131.13 ? 74  ARG B CB  1 
ATOM   6701  C  CG  . ARG B 1 74  ? 209.012 228.930 303.581 1.00 131.51 ? 74  ARG B CG  1 
ATOM   6702  C  CD  . ARG B 1 74  ? 207.925 227.871 303.666 1.00 135.55 ? 74  ARG B CD  1 
ATOM   6703  N  NE  . ARG B 1 74  ? 208.260 226.653 302.937 1.00 140.25 ? 74  ARG B NE  1 
ATOM   6704  C  CZ  . ARG B 1 74  ? 209.204 225.791 303.295 1.00 144.45 ? 74  ARG B CZ  1 
ATOM   6705  N  NH1 . ARG B 1 74  ? 209.964 225.998 304.357 1.00 145.98 ? 74  ARG B NH1 1 
ATOM   6706  N  NH2 . ARG B 1 74  ? 209.387 224.692 302.571 1.00 146.88 ? 74  ARG B NH2 1 
ATOM   6707  N  N   . PRO B 1 75  ? 209.899 231.792 301.462 1.00 130.50 ? 75  PRO B N   1 
ATOM   6708  C  CA  . PRO B 1 75  ? 209.597 233.181 301.844 1.00 131.44 ? 75  PRO B CA  1 
ATOM   6709  C  C   . PRO B 1 75  ? 208.729 233.904 300.838 1.00 128.65 ? 75  PRO B C   1 
ATOM   6710  O  O   . PRO B 1 75  ? 208.002 234.833 301.211 1.00 128.25 ? 75  PRO B O   1 
ATOM   6711  C  CB  . PRO B 1 75  ? 210.987 233.828 301.954 1.00 131.07 ? 75  PRO B CB  1 
ATOM   6712  C  CG  . PRO B 1 75  ? 211.943 232.690 302.065 1.00 131.83 ? 75  PRO B CG  1 
ATOM   6713  C  CD  . PRO B 1 75  ? 211.343 231.605 301.237 1.00 131.64 ? 75  PRO B CD  1 
ATOM   6714  N  N   . ALA B 1 76  ? 208.775 233.504 299.568 1.00 128.17 ? 76  ALA B N   1 
ATOM   6715  C  CA  . ALA B 1 76  ? 207.952 234.179 298.575 1.00 129.41 ? 76  ALA B CA  1 
ATOM   6716  C  C   . ALA B 1 76  ? 206.474 233.904 298.798 1.00 132.39 ? 76  ALA B C   1 
ATOM   6717  O  O   . ALA B 1 76  ? 205.641 234.790 298.578 1.00 132.40 ? 76  ALA B O   1 
ATOM   6718  C  CB  . ALA B 1 76  ? 208.370 233.750 297.169 1.00 127.06 ? 76  ALA B CB  1 
ATOM   6719  N  N   . HIS B 1 77  ? 206.135 232.698 299.249 1.00 135.22 ? 77  HIS B N   1 
ATOM   6720  C  CA  . HIS B 1 77  ? 204.755 232.223 299.270 1.00 136.78 ? 77  HIS B CA  1 
ATOM   6721  C  C   . HIS B 1 77  ? 203.828 233.050 300.162 1.00 135.02 ? 77  HIS B C   1 
ATOM   6722  O  O   . HIS B 1 77  ? 202.695 233.329 299.752 1.00 134.71 ? 77  HIS B O   1 
ATOM   6723  C  CB  . HIS B 1 77  ? 204.708 230.748 299.676 1.00 133.76 ? 77  HIS B CB  1 
ATOM   6724  C  CG  . HIS B 1 77  ? 203.687 229.953 298.922 1.00 128.54 ? 77  HIS B CG  1 
ATOM   6725  N  ND1 . HIS B 1 77  ? 202.331 230.121 299.103 1.00 127.27 ? 77  HIS B ND1 1 
ATOM   6726  C  CD2 . HIS B 1 77  ? 203.824 229.001 297.968 1.00 125.37 ? 77  HIS B CD2 1 
ATOM   6727  C  CE1 . HIS B 1 77  ? 201.677 229.298 298.303 1.00 125.09 ? 77  HIS B CE1 1 
ATOM   6728  N  NE2 . HIS B 1 77  ? 202.559 228.609 297.601 1.00 123.88 ? 77  HIS B NE2 1 
ATOM   6729  N  N   . PRO B 1 78  ? 204.229 233.439 301.381 1.00 130.10 ? 78  PRO B N   1 
ATOM   6730  C  CA  . PRO B 1 78  ? 203.323 234.280 302.184 1.00 130.52 ? 78  PRO B CA  1 
ATOM   6731  C  C   . PRO B 1 78  ? 202.944 235.576 301.491 1.00 133.53 ? 78  PRO B C   1 
ATOM   6732  O  O   . PRO B 1 78  ? 201.752 235.837 301.275 1.00 131.99 ? 78  PRO B O   1 
ATOM   6733  C  CB  . PRO B 1 78  ? 204.125 234.522 303.468 1.00 132.16 ? 78  PRO B CB  1 
ATOM   6734  C  CG  . PRO B 1 78  ? 205.040 233.369 303.554 1.00 128.67 ? 78  PRO B CG  1 
ATOM   6735  C  CD  . PRO B 1 78  ? 205.434 233.081 302.148 1.00 125.72 ? 78  PRO B CD  1 
ATOM   6736  N  N   . GLU B 1 79  ? 203.932 236.390 301.111 1.00 134.90 ? 79  GLU B N   1 
ATOM   6737  C  CA  . GLU B 1 79  ? 203.634 237.651 300.441 1.00 135.92 ? 79  GLU B CA  1 
ATOM   6738  C  C   . GLU B 1 79  ? 202.696 237.423 299.266 1.00 133.80 ? 79  GLU B C   1 
ATOM   6739  O  O   . GLU B 1 79  ? 201.671 238.102 299.131 1.00 134.85 ? 79  GLU B O   1 
ATOM   6740  C  CB  . GLU B 1 79  ? 204.930 238.318 299.978 1.00 138.10 ? 79  GLU B CB  1 
ATOM   6741  C  CG  . GLU B 1 79  ? 204.733 239.704 299.387 1.00 140.01 ? 79  GLU B CG  1 
ATOM   6742  C  CD  . GLU B 1 79  ? 204.726 240.793 300.442 1.00 139.04 ? 79  GLU B CD  1 
ATOM   6743  O  OE1 . GLU B 1 79  ? 204.887 240.467 301.637 1.00 136.84 ? 79  GLU B OE1 1 
ATOM   6744  O  OE2 . GLU B 1 79  ? 204.556 241.975 300.077 1.00 137.41 ? 79  GLU B OE2 1 
ATOM   6745  N  N   . TYR B 1 80  ? 203.012 236.426 298.437 1.00 132.59 ? 80  TYR B N   1 
ATOM   6746  C  CA  . TYR B 1 80  ? 202.141 236.048 297.333 1.00 133.43 ? 80  TYR B CA  1 
ATOM   6747  C  C   . TYR B 1 80  ? 200.697 235.910 297.797 1.00 131.83 ? 80  TYR B C   1 
ATOM   6748  O  O   . TYR B 1 80  ? 199.810 236.635 297.334 1.00 132.43 ? 80  TYR B O   1 
ATOM   6749  C  CB  . TYR B 1 80  ? 202.635 234.742 296.709 1.00 134.05 ? 80  TYR B CB  1 
ATOM   6750  C  CG  . TYR B 1 80  ? 203.894 234.890 295.883 1.00 138.76 ? 80  TYR B CG  1 
ATOM   6751  C  CD1 . TYR B 1 80  ? 204.391 236.145 295.555 1.00 138.22 ? 80  TYR B CD1 1 
ATOM   6752  C  CD2 . TYR B 1 80  ? 204.586 233.774 295.433 1.00 136.72 ? 80  TYR B CD2 1 
ATOM   6753  C  CE1 . TYR B 1 80  ? 205.542 236.284 294.802 1.00 138.23 ? 80  TYR B CE1 1 
ATOM   6754  C  CE2 . TYR B 1 80  ? 205.737 233.902 294.679 1.00 136.98 ? 80  TYR B CE2 1 
ATOM   6755  C  CZ  . TYR B 1 80  ? 206.211 235.159 294.367 1.00 138.54 ? 80  TYR B CZ  1 
ATOM   6756  O  OH  . TYR B 1 80  ? 207.356 235.292 293.616 1.00 134.55 ? 80  TYR B OH  1 
ATOM   6757  N  N   . ILE B 1 81  ? 200.447 235.003 298.745 1.00 131.60 ? 81  ILE B N   1 
ATOM   6758  C  CA  . ILE B 1 81  ? 199.069 234.802 299.178 1.00 132.49 ? 81  ILE B CA  1 
ATOM   6759  C  C   . ILE B 1 81  ? 198.556 236.052 299.870 1.00 132.17 ? 81  ILE B C   1 
ATOM   6760  O  O   . ILE B 1 81  ? 197.369 236.385 299.772 1.00 132.96 ? 81  ILE B O   1 
ATOM   6761  C  CB  . ILE B 1 81  ? 198.939 233.544 300.064 1.00 132.21 ? 81  ILE B CB  1 
ATOM   6762  C  CG1 . ILE B 1 81  ? 199.920 233.573 301.231 1.00 131.10 ? 81  ILE B CG1 1 
ATOM   6763  C  CG2 . ILE B 1 81  ? 199.157 232.288 299.235 1.00 125.25 ? 81  ILE B CG2 1 
ATOM   6764  C  CD1 . ILE B 1 81  ? 199.818 232.387 302.151 1.00 131.91 ? 81  ILE B CD1 1 
ATOM   6765  N  N   . ARG B 1 82  ? 199.443 236.786 300.545 1.00 130.86 ? 82  ARG B N   1 
ATOM   6766  C  CA  . ARG B 1 82  ? 199.060 238.092 301.065 1.00 132.21 ? 82  ARG B CA  1 
ATOM   6767  C  C   . ARG B 1 82  ? 198.574 238.987 299.937 1.00 134.11 ? 82  ARG B C   1 
ATOM   6768  O  O   . ARG B 1 82  ? 197.476 239.553 300.002 1.00 132.37 ? 82  ARG B O   1 
ATOM   6769  C  CB  . ARG B 1 82  ? 200.237 238.732 301.800 1.00 134.06 ? 82  ARG B CB  1 
ATOM   6770  C  CG  . ARG B 1 82  ? 199.908 240.061 302.460 1.00 134.87 ? 82  ARG B CG  1 
ATOM   6771  C  CD  . ARG B 1 82  ? 201.157 240.725 303.016 1.00 133.23 ? 82  ARG B CD  1 
ATOM   6772  N  NE  . ARG B 1 82  ? 200.948 242.141 303.291 1.00 133.10 ? 82  ARG B NE  1 
ATOM   6773  C  CZ  . ARG B 1 82  ? 201.873 243.079 303.135 1.00 130.97 ? 82  ARG B CZ  1 
ATOM   6774  N  NH1 . ARG B 1 82  ? 203.089 242.786 302.706 1.00 131.66 ? 82  ARG B NH1 1 
ATOM   6775  N  NH2 . ARG B 1 82  ? 201.569 244.343 303.418 1.00 126.49 ? 82  ARG B NH2 1 
ATOM   6776  N  N   . HIS B 1 83  ? 199.363 239.088 298.864 1.00 136.85 ? 83  HIS B N   1 
ATOM   6777  C  CA  . HIS B 1 83  ? 198.905 239.821 297.692 1.00 137.09 ? 83  HIS B CA  1 
ATOM   6778  C  C   . HIS B 1 83  ? 197.570 239.276 297.215 1.00 137.02 ? 83  HIS B C   1 
ATOM   6779  O  O   . HIS B 1 83  ? 196.682 240.039 296.817 1.00 136.12 ? 83  HIS B O   1 
ATOM   6780  C  CB  . HIS B 1 83  ? 199.950 239.745 296.579 1.00 138.67 ? 83  HIS B CB  1 
ATOM   6781  C  CG  . HIS B 1 83  ? 199.658 240.639 295.414 1.00 138.13 ? 83  HIS B CG  1 
ATOM   6782  N  ND1 . HIS B 1 83  ? 198.847 240.257 294.367 1.00 138.64 ? 83  HIS B ND1 1 
ATOM   6783  C  CD2 . HIS B 1 83  ? 200.069 241.898 295.131 1.00 134.75 ? 83  HIS B CD2 1 
ATOM   6784  C  CE1 . HIS B 1 83  ? 198.771 241.241 293.489 1.00 135.57 ? 83  HIS B CE1 1 
ATOM   6785  N  NE2 . HIS B 1 83  ? 199.503 242.249 293.929 1.00 132.61 ? 83  HIS B NE2 1 
ATOM   6786  N  N   . ASN B 1 84  ? 197.394 237.955 297.294 1.00 137.14 ? 84  ASN B N   1 
ATOM   6787  C  CA  . ASN B 1 84  ? 196.121 237.360 296.909 1.00 137.44 ? 84  ASN B CA  1 
ATOM   6788  C  C   . ASN B 1 84  ? 194.990 237.898 297.772 1.00 136.11 ? 84  ASN B C   1 
ATOM   6789  O  O   . ASN B 1 84  ? 193.955 238.333 297.255 1.00 134.37 ? 84  ASN B O   1 
ATOM   6790  C  CB  . ASN B 1 84  ? 196.201 235.837 297.002 1.00 137.51 ? 84  ASN B CB  1 
ATOM   6791  C  CG  . ASN B 1 84  ? 195.039 235.153 296.310 1.00 139.00 ? 84  ASN B CG  1 
ATOM   6792  O  OD1 . ASN B 1 84  ? 193.955 235.024 296.877 1.00 140.64 ? 84  ASN B OD1 1 
ATOM   6793  N  ND2 . ASN B 1 84  ? 195.256 234.725 295.073 1.00 136.18 ? 84  ASN B ND2 1 
ATOM   6794  N  N   . ARG B 1 85  ? 195.180 237.915 299.093 1.00 135.54 ? 85  ARG B N   1 
ATOM   6795  C  CA  . ARG B 1 85  ? 194.110 238.452 299.919 1.00 136.36 ? 85  ARG B CA  1 
ATOM   6796  C  C   . ARG B 1 85  ? 194.006 239.961 299.788 1.00 136.99 ? 85  ARG B C   1 
ATOM   6797  O  O   . ARG B 1 85  ? 193.037 240.547 300.282 1.00 138.88 ? 85  ARG B O   1 
ATOM   6798  C  CB  . ARG B 1 85  ? 194.291 238.047 301.385 1.00 138.10 ? 85  ARG B CB  1 
ATOM   6799  C  CG  . ARG B 1 85  ? 195.616 238.425 302.000 1.00 137.20 ? 85  ARG B CG  1 
ATOM   6800  C  CD  . ARG B 1 85  ? 196.061 237.403 303.029 1.00 138.33 ? 85  ARG B CD  1 
ATOM   6801  N  NE  . ARG B 1 85  ? 196.456 236.148 302.401 1.00 139.44 ? 85  ARG B NE  1 
ATOM   6802  C  CZ  . ARG B 1 85  ? 195.709 235.052 302.386 1.00 141.37 ? 85  ARG B CZ  1 
ATOM   6803  N  NH1 . ARG B 1 85  ? 194.516 235.022 302.958 1.00 143.27 ? 85  ARG B NH1 1 
ATOM   6804  N  NH2 . ARG B 1 85  ? 196.169 233.961 301.782 1.00 140.87 ? 85  ARG B NH2 1 
ATOM   6805  N  N   . GLU B 1 86  ? 194.976 240.595 299.132 1.00 136.40 ? 86  GLU B N   1 
ATOM   6806  C  CA  . GLU B 1 86  ? 194.846 241.984 298.727 1.00 139.29 ? 86  GLU B CA  1 
ATOM   6807  C  C   . GLU B 1 86  ? 194.429 242.132 297.272 1.00 141.46 ? 86  GLU B C   1 
ATOM   6808  O  O   . GLU B 1 86  ? 193.984 243.216 296.879 1.00 145.53 ? 86  GLU B O   1 
ATOM   6809  C  CB  . GLU B 1 86  ? 196.165 242.733 298.953 1.00 138.49 ? 86  GLU B CB  1 
ATOM   6810  C  CG  . GLU B 1 86  ? 196.520 242.941 300.417 1.00 138.05 ? 86  GLU B CG  1 
ATOM   6811  C  CD  . GLU B 1 86  ? 197.731 243.835 300.601 1.00 137.01 ? 86  GLU B CD  1 
ATOM   6812  O  OE1 . GLU B 1 86  ? 198.069 244.581 299.659 1.00 138.05 ? 86  GLU B OE1 1 
ATOM   6813  O  OE2 . GLU B 1 86  ? 198.344 243.791 301.689 1.00 133.23 ? 86  GLU B OE2 1 
ATOM   6814  N  N   . GLY B 1 87  ? 194.567 241.075 296.469 1.00 137.81 ? 87  GLY B N   1 
ATOM   6815  C  CA  . GLY B 1 87  ? 194.199 241.175 295.066 1.00 139.15 ? 87  GLY B CA  1 
ATOM   6816  C  C   . GLY B 1 87  ? 192.709 241.363 294.856 1.00 141.10 ? 87  GLY B C   1 
ATOM   6817  O  O   . GLY B 1 87  ? 192.287 242.202 294.055 1.00 140.53 ? 87  GLY B O   1 
ATOM   6818  N  N   . GLY B 1 88  ? 191.893 240.588 295.568 1.00 141.10 ? 88  GLY B N   1 
ATOM   6819  C  CA  . GLY B 1 88  ? 190.455 240.663 295.429 1.00 142.23 ? 88  GLY B CA  1 
ATOM   6820  C  C   . GLY B 1 88  ? 189.890 239.959 294.216 1.00 145.47 ? 88  GLY B C   1 
ATOM   6821  O  O   . GLY B 1 88  ? 188.669 239.994 294.014 1.00 145.01 ? 88  GLY B O   1 
ATOM   6822  N  N   . LYS B 1 89  ? 190.729 239.324 293.404 1.00 146.90 ? 89  LYS B N   1 
ATOM   6823  C  CA  . LYS B 1 89  ? 190.268 238.651 292.200 1.00 145.86 ? 89  LYS B CA  1 
ATOM   6824  C  C   . LYS B 1 89  ? 189.673 237.288 292.533 1.00 146.97 ? 89  LYS B C   1 
ATOM   6825  O  O   . LYS B 1 89  ? 190.146 236.579 293.425 1.00 148.07 ? 89  LYS B O   1 
ATOM   6826  C  CB  . LYS B 1 89  ? 191.417 238.491 291.203 1.00 142.83 ? 89  LYS B CB  1 
ATOM   6827  C  CG  . LYS B 1 89  ? 192.665 237.854 291.793 1.00 141.19 ? 89  LYS B CG  1 
ATOM   6828  C  CD  . LYS B 1 89  ? 193.843 237.954 290.838 1.00 142.68 ? 89  LYS B CD  1 
ATOM   6829  C  CE  . LYS B 1 89  ? 195.059 237.221 291.382 1.00 137.69 ? 89  LYS B CE  1 
ATOM   6830  N  NZ  . LYS B 1 89  ? 196.226 237.321 290.463 1.00 137.58 ? 89  LYS B NZ  1 
ATOM   6831  N  N   . ALA B 1 90  ? 188.620 236.928 291.801 1.00 148.50 ? 90  ALA B N   1 
ATOM   6832  C  CA  . ALA B 1 90  ? 187.954 235.647 291.986 1.00 147.59 ? 90  ALA B CA  1 
ATOM   6833  C  C   . ALA B 1 90  ? 188.668 234.494 291.294 1.00 145.18 ? 90  ALA B C   1 
ATOM   6834  O  O   . ALA B 1 90  ? 188.354 233.333 291.576 1.00 142.25 ? 90  ALA B O   1 
ATOM   6835  C  CB  . ALA B 1 90  ? 186.508 235.725 291.483 1.00 143.15 ? 90  ALA B CB  1 
ATOM   6836  N  N   . ARG B 1 91  ? 189.613 234.780 290.401 1.00 143.63 ? 91  ARG B N   1 
ATOM   6837  C  CA  . ARG B 1 91  ? 190.361 233.751 289.697 1.00 137.40 ? 91  ARG B CA  1 
ATOM   6838  C  C   . ARG B 1 91  ? 191.849 233.986 289.891 1.00 136.02 ? 91  ARG B C   1 
ATOM   6839  O  O   . ARG B 1 91  ? 192.313 235.127 289.945 1.00 138.12 ? 91  ARG B O   1 
ATOM   6840  C  CB  . ARG B 1 91  ? 190.030 233.734 288.201 1.00 134.13 ? 91  ARG B CB  1 
ATOM   6841  C  CG  . ARG B 1 91  ? 188.547 233.630 287.902 1.00 133.91 ? 91  ARG B CG  1 
ATOM   6842  C  CD  . ARG B 1 91  ? 187.967 232.332 288.435 1.00 135.17 ? 91  ARG B CD  1 
ATOM   6843  N  NE  . ARG B 1 91  ? 186.523 232.263 288.244 1.00 138.64 ? 91  ARG B NE  1 
ATOM   6844  C  CZ  . ARG B 1 91  ? 185.932 231.889 287.118 1.00 143.19 ? 91  ARG B CZ  1 
ATOM   6845  N  NH1 . ARG B 1 91  ? 186.634 231.539 286.052 1.00 146.33 ? 91  ARG B NH1 1 
ATOM   6846  N  NH2 . ARG B 1 91  ? 184.604 231.865 287.059 1.00 142.67 ? 91  ARG B NH2 1 
ATOM   6847  N  N   . VAL B 1 92  ? 192.595 232.892 289.991 1.00 133.15 ? 92  VAL B N   1 
ATOM   6848  C  CA  . VAL B 1 92  ? 194.039 232.934 290.170 1.00 131.77 ? 92  VAL B CA  1 
ATOM   6849  C  C   . VAL B 1 92  ? 194.672 232.527 288.850 1.00 131.22 ? 92  VAL B C   1 
ATOM   6850  O  O   . VAL B 1 92  ? 194.517 231.384 288.402 1.00 129.52 ? 92  VAL B O   1 
ATOM   6851  C  CB  . VAL B 1 92  ? 194.503 232.018 291.308 1.00 126.65 ? 92  VAL B CB  1 
ATOM   6852  C  CG1 . VAL B 1 92  ? 195.990 231.746 291.188 1.00 123.98 ? 92  VAL B CG1 1 
ATOM   6853  C  CG2 . VAL B 1 92  ? 194.179 232.642 292.652 1.00 126.33 ? 92  VAL B CG2 1 
ATOM   6854  N  N   . GLU B 1 93  ? 195.383 233.459 288.221 1.00 136.12 ? 93  GLU B N   1 
ATOM   6855  C  CA  . GLU B 1 93  ? 196.128 233.130 287.015 1.00 138.93 ? 93  GLU B CA  1 
ATOM   6856  C  C   . GLU B 1 93  ? 197.387 232.334 287.320 1.00 136.48 ? 93  GLU B C   1 
ATOM   6857  O  O   . GLU B 1 93  ? 197.933 231.690 286.419 1.00 134.80 ? 93  GLU B O   1 
ATOM   6858  C  CB  . GLU B 1 93  ? 196.494 234.405 286.252 1.00 141.08 ? 93  GLU B CB  1 
ATOM   6859  C  CG  . GLU B 1 93  ? 195.316 235.326 285.977 1.00 141.87 ? 93  GLU B CG  1 
ATOM   6860  C  CD  . GLU B 1 93  ? 195.216 236.461 286.978 1.00 146.96 ? 93  GLU B CD  1 
ATOM   6861  O  OE1 . GLU B 1 93  ? 195.743 236.313 288.101 1.00 147.95 ? 93  GLU B OE1 1 
ATOM   6862  O  OE2 . GLU B 1 93  ? 194.612 237.501 286.643 1.00 150.07 ? 93  GLU B OE2 1 
ATOM   6863  N  N   . GLY B 1 94  ? 197.854 232.363 288.565 1.00 133.98 ? 94  GLY B N   1 
ATOM   6864  C  CA  . GLY B 1 94  ? 199.035 231.614 288.927 1.00 130.39 ? 94  GLY B CA  1 
ATOM   6865  C  C   . GLY B 1 94  ? 198.774 230.124 288.998 1.00 126.64 ? 94  GLY B C   1 
ATOM   6866  O  O   . GLY B 1 94  ? 197.636 229.656 288.985 1.00 126.51 ? 94  GLY B O   1 
ATOM   6867  N  N   . MET B 1 95  ? 199.872 229.369 289.064 1.00 125.91 ? 95  MET B N   1 
ATOM   6868  C  CA  . MET B 1 95  ? 199.853 227.910 289.088 1.00 124.47 ? 95  MET B CA  1 
ATOM   6869  C  C   . MET B 1 95  ? 199.155 227.340 287.860 1.00 124.16 ? 95  MET B C   1 
ATOM   6870  O  O   . MET B 1 95  ? 198.839 226.146 287.817 1.00 120.79 ? 95  MET B O   1 
ATOM   6871  C  CB  . MET B 1 95  ? 199.199 227.378 290.371 1.00 123.75 ? 95  MET B CB  1 
ATOM   6872  C  CG  . MET B 1 95  ? 199.351 228.271 291.596 1.00 123.87 ? 95  MET B CG  1 
ATOM   6873  S  SD  . MET B 1 95  ? 199.700 227.328 293.091 1.00 130.90 ? 95  MET B SD  1 
ATOM   6874  C  CE  . MET B 1 95  ? 198.077 226.668 293.460 1.00 119.64 ? 95  MET B CE  1 
ATOM   6875  N  N   . SER B 1 96  ? 198.910 228.182 286.854 1.00 126.56 ? 96  SER B N   1 
ATOM   6876  C  CA  . SER B 1 96  ? 198.337 227.697 285.607 1.00 125.57 ? 96  SER B CA  1 
ATOM   6877  C  C   . SER B 1 96  ? 199.358 226.946 284.766 1.00 122.59 ? 96  SER B C   1 
ATOM   6878  O  O   . SER B 1 96  ? 198.970 226.189 283.870 1.00 120.75 ? 96  SER B O   1 
ATOM   6879  C  CB  . SER B 1 96  ? 197.755 228.862 284.806 1.00 124.76 ? 96  SER B CB  1 
ATOM   6880  O  OG  . SER B 1 96  ? 198.692 229.918 284.690 1.00 129.34 ? 96  SER B OG  1 
ATOM   6881  N  N   . ALA B 1 97  ? 200.645 227.134 285.033 1.00 123.14 ? 97  ALA B N   1 
ATOM   6882  C  CA  . ALA B 1 97  ? 201.687 226.457 284.287 1.00 117.57 ? 97  ALA B CA  1 
ATOM   6883  C  C   . ALA B 1 97  ? 202.223 225.276 285.089 1.00 113.35 ? 97  ALA B C   1 
ATOM   6884  O  O   . ALA B 1 97  ? 201.864 225.061 286.248 1.00 111.36 ? 97  ALA B O   1 
ATOM   6885  C  CB  . ALA B 1 97  ? 202.805 227.434 283.930 1.00 115.21 ? 97  ALA B CB  1 
ATOM   6886  N  N   . GLU B 1 98  ? 203.101 224.504 284.460 1.00 113.61 ? 98  GLU B N   1 
ATOM   6887  C  CA  . GLU B 1 98  ? 203.701 223.354 285.115 1.00 113.40 ? 98  GLU B CA  1 
ATOM   6888  C  C   . GLU B 1 98  ? 204.563 223.802 286.288 1.00 113.50 ? 98  GLU B C   1 
ATOM   6889  O  O   . GLU B 1 98  ? 205.098 224.913 286.307 1.00 113.39 ? 98  GLU B O   1 
ATOM   6890  C  CB  . GLU B 1 98  ? 204.534 222.554 284.116 1.00 112.40 ? 98  GLU B CB  1 
ATOM   6891  C  CG  . GLU B 1 98  ? 206.027 222.806 284.201 1.00 112.54 ? 98  GLU B CG  1 
ATOM   6892  C  CD  . GLU B 1 98  ? 206.444 224.098 283.523 1.00 114.47 ? 98  GLU B CD  1 
ATOM   6893  O  OE1 . GLU B 1 98  ? 205.576 224.766 282.922 1.00 114.94 ? 98  GLU B OE1 1 
ATOM   6894  O  OE2 . GLU B 1 98  ? 207.641 224.448 283.596 1.00 111.84 ? 98  GLU B OE2 1 
ATOM   6895  N  N   . LEU B 1 99  ? 204.678 222.933 287.288 1.00 115.25 ? 99  LEU B N   1 
ATOM   6896  C  CA  . LEU B 1 99  ? 205.411 223.273 288.497 1.00 117.12 ? 99  LEU B CA  1 
ATOM   6897  C  C   . LEU B 1 99  ? 206.220 222.073 288.961 1.00 116.84 ? 99  LEU B C   1 
ATOM   6898  O  O   . LEU B 1 99  ? 205.944 220.928 288.596 1.00 114.92 ? 99  LEU B O   1 
ATOM   6899  C  CB  . LEU B 1 99  ? 204.470 223.744 289.613 1.00 117.07 ? 99  LEU B CB  1 
ATOM   6900  C  CG  . LEU B 1 99  ? 203.784 225.094 289.386 1.00 112.88 ? 99  LEU B CG  1 
ATOM   6901  C  CD1 . LEU B 1 99  ? 202.740 225.360 290.459 1.00 112.45 ? 99  LEU B CD1 1 
ATOM   6902  C  CD2 . LEU B 1 99  ? 204.808 226.214 289.339 1.00 112.87 ? 99  LEU B CD2 1 
ATOM   6903  N  N   . GLN B 1 100 ? 207.230 222.356 289.777 1.00 118.81 ? 100 GLN B N   1 
ATOM   6904  C  CA  . GLN B 1 100 ? 208.110 221.342 290.340 1.00 123.91 ? 100 GLN B CA  1 
ATOM   6905  C  C   . GLN B 1 100 ? 207.841 221.214 291.832 1.00 127.49 ? 100 GLN B C   1 
ATOM   6906  O  O   . GLN B 1 100 ? 207.823 222.217 292.553 1.00 125.92 ? 100 GLN B O   1 
ATOM   6907  C  CB  . GLN B 1 100 ? 209.577 221.695 290.095 1.00 127.69 ? 100 GLN B CB  1 
ATOM   6908  C  CG  . GLN B 1 100 ? 210.554 220.613 290.516 1.00 134.22 ? 100 GLN B CG  1 
ATOM   6909  C  CD  . GLN B 1 100 ? 211.926 220.794 289.900 1.00 136.48 ? 100 GLN B CD  1 
ATOM   6910  O  OE1 . GLN B 1 100 ? 212.541 219.838 289.430 1.00 139.81 ? 100 GLN B OE1 1 
ATOM   6911  N  NE2 . GLN B 1 100 ? 212.417 222.029 289.903 1.00 131.37 ? 100 GLN B NE2 1 
ATOM   6912  N  N   . LEU B 1 101 ? 207.633 219.984 292.289 1.00 128.36 ? 101 LEU B N   1 
ATOM   6913  C  CA  . LEU B 1 101 ? 207.356 219.685 293.688 1.00 127.02 ? 101 LEU B CA  1 
ATOM   6914  C  C   . LEU B 1 101 ? 208.482 218.875 294.306 1.00 128.94 ? 101 LEU B C   1 
ATOM   6915  O  O   . LEU B 1 101 ? 208.883 217.841 293.763 1.00 129.50 ? 101 LEU B O   1 
ATOM   6916  C  CB  . LEU B 1 101 ? 206.032 218.941 293.835 1.00 123.82 ? 101 LEU B CB  1 
ATOM   6917  C  CG  . LEU B 1 101 ? 204.876 219.779 294.366 1.00 125.80 ? 101 LEU B CG  1 
ATOM   6918  C  CD1 . LEU B 1 101 ? 205.100 219.927 295.844 1.00 131.48 ? 101 LEU B CD1 1 
ATOM   6919  C  CD2 . LEU B 1 101 ? 204.860 221.155 293.734 1.00 125.68 ? 101 LEU B CD2 1 
ATOM   6920  N  N   . GLU B 1 102 ? 208.977 219.347 295.446 1.00 129.94 ? 102 GLU B N   1 
ATOM   6921  C  CA  . GLU B 1 102 ? 209.955 218.621 296.239 1.00 132.16 ? 102 GLU B CA  1 
ATOM   6922  C  C   . GLU B 1 102 ? 209.232 217.593 297.096 1.00 135.53 ? 102 GLU B C   1 
ATOM   6923  O  O   . GLU B 1 102 ? 208.257 217.921 297.781 1.00 135.83 ? 102 GLU B O   1 
ATOM   6924  C  CB  . GLU B 1 102 ? 210.752 219.583 297.119 1.00 133.44 ? 102 GLU B CB  1 
ATOM   6925  C  CG  . GLU B 1 102 ? 211.924 218.944 297.845 1.00 137.89 ? 102 GLU B CG  1 
ATOM   6926  C  CD  . GLU B 1 102 ? 212.795 219.964 298.555 1.00 144.18 ? 102 GLU B CD  1 
ATOM   6927  O  OE1 . GLU B 1 102 ? 212.247 220.783 299.323 1.00 149.36 ? 102 GLU B OE1 1 
ATOM   6928  O  OE2 . GLU B 1 102 ? 214.026 219.948 298.343 1.00 141.33 ? 102 GLU B OE2 1 
ATOM   6929  N  N   . LYS B 1 103 ? 209.703 216.351 297.050 1.00 138.02 ? 103 LYS B N   1 
ATOM   6930  C  CA  . LYS B 1 103 ? 209.089 215.278 297.812 1.00 136.63 ? 103 LYS B CA  1 
ATOM   6931  C  C   . LYS B 1 103 ? 209.633 215.264 299.240 1.00 138.25 ? 103 LYS B C   1 
ATOM   6932  O  O   . LYS B 1 103 ? 210.489 216.068 299.617 1.00 138.23 ? 103 LYS B O   1 
ATOM   6933  C  CB  . LYS B 1 103 ? 209.314 213.936 297.119 1.00 133.21 ? 103 LYS B CB  1 
ATOM   6934  C  CG  . LYS B 1 103 ? 208.386 213.682 295.944 1.00 127.19 ? 103 LYS B CG  1 
ATOM   6935  C  CD  . LYS B 1 103 ? 208.316 212.201 295.609 1.00 126.65 ? 103 LYS B CD  1 
ATOM   6936  C  CE  . LYS B 1 103 ? 207.242 211.920 294.571 1.00 123.44 ? 103 LYS B CE  1 
ATOM   6937  N  NZ  . LYS B 1 103 ? 207.141 210.468 294.257 1.00 122.95 ? 103 LYS B NZ  1 
ATOM   6938  N  N   . LYS B 1 104 ? 209.121 214.334 300.048 1.00 137.74 ? 104 LYS B N   1 
ATOM   6939  C  CA  . LYS B 1 104 ? 209.564 214.234 301.434 1.00 137.49 ? 104 LYS B CA  1 
ATOM   6940  C  C   . LYS B 1 104 ? 211.043 213.879 301.515 1.00 139.44 ? 104 LYS B C   1 
ATOM   6941  O  O   . LYS B 1 104 ? 211.777 214.427 302.345 1.00 138.46 ? 104 LYS B O   1 
ATOM   6942  C  CB  . LYS B 1 104 ? 208.720 213.201 302.181 1.00 135.91 ? 104 LYS B CB  1 
ATOM   6943  C  CG  . LYS B 1 104 ? 209.220 212.885 303.581 1.00 136.10 ? 104 LYS B CG  1 
ATOM   6944  C  CD  . LYS B 1 104 ? 208.190 212.096 304.369 1.00 134.80 ? 104 LYS B CD  1 
ATOM   6945  C  CE  . LYS B 1 104 ? 208.711 211.737 305.751 1.00 133.35 ? 104 LYS B CE  1 
ATOM   6946  N  NZ  . LYS B 1 104 ? 207.744 210.897 306.511 1.00 131.95 ? 104 LYS B NZ  1 
ATOM   6947  N  N   . ASP B 1 105 ? 211.500 212.972 300.656 1.00 139.99 ? 105 ASP B N   1 
ATOM   6948  C  CA  . ASP B 1 105 ? 212.898 212.563 300.632 1.00 140.48 ? 105 ASP B CA  1 
ATOM   6949  C  C   . ASP B 1 105 ? 213.792 213.553 299.894 1.00 140.68 ? 105 ASP B C   1 
ATOM   6950  O  O   . ASP B 1 105 ? 214.982 213.272 299.710 1.00 139.53 ? 105 ASP B O   1 
ATOM   6951  C  CB  . ASP B 1 105 ? 213.030 211.172 300.004 1.00 138.15 ? 105 ASP B CB  1 
ATOM   6952  C  CG  . ASP B 1 105 ? 212.290 211.054 298.686 1.00 135.04 ? 105 ASP B CG  1 
ATOM   6953  O  OD1 . ASP B 1 105 ? 211.689 212.056 298.246 1.00 133.83 ? 105 ASP B OD1 1 
ATOM   6954  O  OD2 . ASP B 1 105 ? 212.309 209.957 298.089 1.00 131.73 ? 105 ASP B OD2 1 
ATOM   6955  N  N   . GLY B 1 106 ? 213.252 214.695 299.469 1.00 139.86 ? 106 GLY B N   1 
ATOM   6956  C  CA  . GLY B 1 106 ? 214.023 215.706 298.782 1.00 137.82 ? 106 GLY B CA  1 
ATOM   6957  C  C   . GLY B 1 106 ? 214.012 215.616 297.272 1.00 137.29 ? 106 GLY B C   1 
ATOM   6958  O  O   . GLY B 1 106 ? 214.542 216.518 296.612 1.00 134.71 ? 106 GLY B O   1 
ATOM   6959  N  N   . SER B 1 107 ? 213.431 214.563 296.704 1.00 138.53 ? 107 SER B N   1 
ATOM   6960  C  CA  . SER B 1 107 ? 213.366 214.442 295.257 1.00 138.76 ? 107 SER B CA  1 
ATOM   6961  C  C   . SER B 1 107 ? 212.371 215.446 294.681 1.00 139.62 ? 107 SER B C   1 
ATOM   6962  O  O   . SER B 1 107 ? 211.413 215.864 295.338 1.00 139.37 ? 107 SER B O   1 
ATOM   6963  C  CB  . SER B 1 107 ? 212.974 213.022 294.852 1.00 137.14 ? 107 SER B CB  1 
ATOM   6964  O  OG  . SER B 1 107 ? 211.632 212.742 295.207 1.00 138.39 ? 107 SER B OG  1 
ATOM   6965  N  N   . LYS B 1 108 ? 212.611 215.831 293.431 1.00 140.51 ? 108 LYS B N   1 
ATOM   6966  C  CA  . LYS B 1 108 ? 211.786 216.806 292.731 1.00 137.09 ? 108 LYS B CA  1 
ATOM   6967  C  C   . LYS B 1 108 ? 211.079 216.126 291.567 1.00 136.29 ? 108 LYS B C   1 
ATOM   6968  O  O   . LYS B 1 108 ? 211.709 215.401 290.790 1.00 135.45 ? 108 LYS B O   1 
ATOM   6969  C  CB  . LYS B 1 108 ? 212.628 217.982 292.232 1.00 134.64 ? 108 LYS B CB  1 
ATOM   6970  C  CG  . LYS B 1 108 ? 213.254 218.807 293.345 1.00 129.24 ? 108 LYS B CG  1 
ATOM   6971  C  CD  . LYS B 1 108 ? 213.970 220.030 292.796 1.00 121.70 ? 108 LYS B CD  1 
ATOM   6972  C  CE  . LYS B 1 108 ? 214.607 220.843 293.912 1.00 110.66 ? 108 LYS B CE  1 
ATOM   6973  N  NZ  . LYS B 1 108 ? 215.324 222.039 293.389 1.00 109.23 ? 108 LYS B NZ  1 
ATOM   6974  N  N   . ILE B 1 109 ? 209.772 216.364 291.454 1.00 135.28 ? 109 ILE B N   1 
ATOM   6975  C  CA  . ILE B 1 109 ? 208.938 215.772 290.418 1.00 134.08 ? 109 ILE B CA  1 
ATOM   6976  C  C   . ILE B 1 109 ? 208.133 216.877 289.746 1.00 128.64 ? 109 ILE B C   1 
ATOM   6977  O  O   . ILE B 1 109 ? 208.074 218.013 290.219 1.00 126.06 ? 109 ILE B O   1 
ATOM   6978  C  CB  . ILE B 1 109 ? 207.995 214.686 290.973 1.00 131.51 ? 109 ILE B CB  1 
ATOM   6979  C  CG1 . ILE B 1 109 ? 207.110 215.270 292.074 1.00 130.68 ? 109 ILE B CG1 1 
ATOM   6980  C  CG2 . ILE B 1 109 ? 208.790 213.499 291.492 1.00 127.43 ? 109 ILE B CG2 1 
ATOM   6981  C  CD1 . ILE B 1 109 ? 205.779 214.570 292.222 1.00 127.05 ? 109 ILE B CD1 1 
ATOM   6982  N  N   . TRP B 1 110 ? 207.504 216.523 288.628 1.00 124.93 ? 110 TRP B N   1 
ATOM   6983  C  CA  . TRP B 1 110 ? 206.644 217.441 287.895 1.00 115.09 ? 110 TRP B CA  1 
ATOM   6984  C  C   . TRP B 1 110 ? 205.200 217.307 288.355 1.00 108.93 ? 110 TRP B C   1 
ATOM   6985  O  O   . TRP B 1 110 ? 204.743 216.213 288.696 1.00 107.90 ? 110 TRP B O   1 
ATOM   6986  C  CB  . TRP B 1 110 ? 206.741 217.183 286.391 1.00 107.86 ? 110 TRP B CB  1 
ATOM   6987  C  CG  . TRP B 1 110 ? 207.963 217.768 285.786 1.00 107.59 ? 110 TRP B CG  1 
ATOM   6988  C  CD1 . TRP B 1 110 ? 208.929 217.113 285.085 1.00 106.68 ? 110 TRP B CD1 1 
ATOM   6989  C  CD2 . TRP B 1 110 ? 208.346 219.143 285.814 1.00 108.29 ? 110 TRP B CD2 1 
ATOM   6990  N  NE1 . TRP B 1 110 ? 209.898 217.997 284.682 1.00 110.05 ? 110 TRP B NE1 1 
ATOM   6991  C  CE2 . TRP B 1 110 ? 209.560 219.252 285.117 1.00 109.74 ? 110 TRP B CE2 1 
ATOM   6992  C  CE3 . TRP B 1 110 ? 207.777 220.294 286.360 1.00 110.04 ? 110 TRP B CE3 1 
ATOM   6993  C  CZ2 . TRP B 1 110 ? 210.220 220.465 284.956 1.00 110.56 ? 110 TRP B CZ2 1 
ATOM   6994  C  CZ3 . TRP B 1 110 ? 208.432 221.491 286.208 1.00 112.06 ? 110 TRP B CZ3 1 
ATOM   6995  C  CH2 . TRP B 1 110 ? 209.639 221.572 285.507 1.00 112.90 ? 110 TRP B CH2 1 
ATOM   6996  N  N   . THR B 1 111 ? 204.484 218.429 288.363 1.00 105.20 ? 111 THR B N   1 
ATOM   6997  C  CA  . THR B 1 111 ? 203.106 218.427 288.815 1.00 102.15 ? 111 THR B CA  1 
ATOM   6998  C  C   . THR B 1 111 ? 202.383 219.637 288.252 1.00 98.55  ? 111 THR B C   1 
ATOM   6999  O  O   . THR B 1 111 ? 202.999 220.598 287.782 1.00 102.20 ? 111 THR B O   1 
ATOM   7000  C  CB  . THR B 1 111 ? 203.013 218.439 290.336 1.00 108.97 ? 111 THR B CB  1 
ATOM   7001  O  OG1 . THR B 1 111 ? 201.636 218.419 290.724 1.00 112.17 ? 111 THR B OG1 1 
ATOM   7002  C  CG2 . THR B 1 111 ? 203.656 219.691 290.869 1.00 113.92 ? 111 THR B CG2 1 
ATOM   7003  N  N   . ARG B 1 112 ? 201.062 219.576 288.312 1.00 95.73  ? 112 ARG B N   1 
ATOM   7004  C  CA  . ARG B 1 112 ? 200.204 220.663 287.884 1.00 97.58  ? 112 ARG B CA  1 
ATOM   7005  C  C   . ARG B 1 112 ? 199.278 221.023 289.030 1.00 98.20  ? 112 ARG B C   1 
ATOM   7006  O  O   . ARG B 1 112 ? 198.892 220.164 289.823 1.00 100.54 ? 112 ARG B O   1 
ATOM   7007  C  CB  . ARG B 1 112 ? 199.385 220.286 286.645 1.00 102.87 ? 112 ARG B CB  1 
ATOM   7008  C  CG  . ARG B 1 112 ? 198.713 221.467 285.964 1.00 107.71 ? 112 ARG B CG  1 
ATOM   7009  C  CD  . ARG B 1 112 ? 199.726 222.378 285.292 1.00 113.90 ? 112 ARG B CD  1 
ATOM   7010  N  NE  . ARG B 1 112 ? 200.192 221.830 284.024 1.00 118.52 ? 112 ARG B NE  1 
ATOM   7011  C  CZ  . ARG B 1 112 ? 199.821 222.282 282.835 1.00 121.43 ? 112 ARG B CZ  1 
ATOM   7012  N  NH1 . ARG B 1 112 ? 198.973 223.291 282.713 1.00 119.81 ? 112 ARG B NH1 1 
ATOM   7013  N  NH2 . ARG B 1 112 ? 200.310 221.707 281.740 1.00 121.47 ? 112 ARG B NH2 1 
ATOM   7014  N  N   . PHE B 1 113 ? 198.930 222.299 289.118 1.00 99.76  ? 113 PHE B N   1 
ATOM   7015  C  CA  . PHE B 1 113 ? 198.152 222.802 290.234 1.00 102.68 ? 113 PHE B CA  1 
ATOM   7016  C  C   . PHE B 1 113 ? 196.934 223.552 289.722 1.00 102.48 ? 113 PHE B C   1 
ATOM   7017  O  O   . PHE B 1 113 ? 196.915 224.069 288.604 1.00 107.26 ? 113 PHE B O   1 
ATOM   7018  C  CB  . PHE B 1 113 ? 198.986 223.730 291.125 1.00 113.14 ? 113 PHE B CB  1 
ATOM   7019  C  CG  . PHE B 1 113 ? 199.740 223.020 292.211 1.00 115.82 ? 113 PHE B CG  1 
ATOM   7020  C  CD1 . PHE B 1 113 ? 200.436 221.856 291.947 1.00 113.53 ? 113 PHE B CD1 1 
ATOM   7021  C  CD2 . PHE B 1 113 ? 199.760 223.528 293.500 1.00 118.39 ? 113 PHE B CD2 1 
ATOM   7022  C  CE1 . PHE B 1 113 ? 201.135 221.206 292.948 1.00 116.87 ? 113 PHE B CE1 1 
ATOM   7023  C  CE2 . PHE B 1 113 ? 200.456 222.883 294.505 1.00 120.97 ? 113 PHE B CE2 1 
ATOM   7024  C  CZ  . PHE B 1 113 ? 201.144 221.721 294.228 1.00 121.14 ? 113 PHE B CZ  1 
ATOM   7025  N  N   . ALA B 1 114 ? 195.908 223.582 290.562 1.00 101.08 ? 114 ALA B N   1 
ATOM   7026  C  CA  . ALA B 1 114 ? 194.730 224.409 290.351 1.00 107.36 ? 114 ALA B CA  1 
ATOM   7027  C  C   . ALA B 1 114 ? 194.359 225.014 291.693 1.00 114.57 ? 114 ALA B C   1 
ATOM   7028  O  O   . ALA B 1 114 ? 194.572 224.380 292.728 1.00 119.47 ? 114 ALA B O   1 
ATOM   7029  C  CB  . ALA B 1 114 ? 193.564 223.595 289.782 1.00 112.75 ? 114 ALA B CB  1 
ATOM   7030  N  N   . LEU B 1 115 ? 193.810 226.222 291.684 1.00 116.42 ? 115 LEU B N   1 
ATOM   7031  C  CA  . LEU B 1 115 ? 193.542 226.952 292.913 1.00 118.64 ? 115 LEU B CA  1 
ATOM   7032  C  C   . LEU B 1 115 ? 192.098 227.425 292.970 1.00 120.29 ? 115 LEU B C   1 
ATOM   7033  O  O   . LEU B 1 115 ? 191.480 227.721 291.945 1.00 123.11 ? 115 LEU B O   1 
ATOM   7034  C  CB  . LEU B 1 115 ? 194.471 228.156 293.042 1.00 120.13 ? 115 LEU B CB  1 
ATOM   7035  C  CG  . LEU B 1 115 ? 194.699 228.670 294.460 1.00 122.37 ? 115 LEU B CG  1 
ATOM   7036  C  CD1 . LEU B 1 115 ? 194.789 227.517 295.443 1.00 123.63 ? 115 LEU B CD1 1 
ATOM   7037  C  CD2 . LEU B 1 115 ? 195.952 229.512 294.499 1.00 121.35 ? 115 LEU B CD2 1 
ATOM   7038  N  N   . SER B 1 116 ? 191.564 227.495 294.185 1.00 121.04 ? 116 SER B N   1 
ATOM   7039  C  CA  . SER B 1 116 ? 190.232 228.036 294.397 1.00 127.50 ? 116 SER B CA  1 
ATOM   7040  C  C   . SER B 1 116 ? 190.218 228.847 295.681 1.00 138.04 ? 116 SER B C   1 
ATOM   7041  O  O   . SER B 1 116 ? 190.684 228.371 296.720 1.00 139.67 ? 116 SER B O   1 
ATOM   7042  C  CB  . SER B 1 116 ? 189.188 226.924 294.472 1.00 126.36 ? 116 SER B CB  1 
ATOM   7043  O  OG  . SER B 1 116 ? 189.245 226.264 295.720 1.00 128.43 ? 116 SER B OG  1 
ATOM   7044  N  N   . LYS B 1 117 ? 189.672 230.058 295.605 1.00 143.55 ? 117 LYS B N   1 
ATOM   7045  C  CA  . LYS B 1 117 ? 189.531 230.948 296.749 1.00 146.38 ? 117 LYS B CA  1 
ATOM   7046  C  C   . LYS B 1 117 ? 188.058 231.060 297.114 1.00 146.90 ? 117 LYS B C   1 
ATOM   7047  O  O   . LYS B 1 117 ? 187.214 231.274 296.238 1.00 145.62 ? 117 LYS B O   1 
ATOM   7048  C  CB  . LYS B 1 117 ? 190.101 232.335 296.443 1.00 146.43 ? 117 LYS B CB  1 
ATOM   7049  C  CG  . LYS B 1 117 ? 189.749 233.387 297.483 1.00 146.77 ? 117 LYS B CG  1 
ATOM   7050  C  CD  . LYS B 1 117 ? 189.506 234.747 296.847 1.00 143.35 ? 117 LYS B CD  1 
ATOM   7051  C  CE  . LYS B 1 117 ? 190.808 235.401 296.422 1.00 140.97 ? 117 LYS B CE  1 
ATOM   7052  N  NZ  . LYS B 1 117 ? 190.581 236.726 295.780 1.00 140.45 ? 117 LYS B NZ  1 
ATOM   7053  N  N   . VAL B 1 118 ? 187.751 230.919 298.401 1.00 146.69 ? 118 VAL B N   1 
ATOM   7054  C  CA  . VAL B 1 118 ? 186.381 230.984 298.887 1.00 150.60 ? 118 VAL B CA  1 
ATOM   7055  C  C   . VAL B 1 118 ? 186.317 231.939 300.068 1.00 152.44 ? 118 VAL B C   1 
ATOM   7056  O  O   . VAL B 1 118 ? 187.301 232.133 300.788 1.00 148.43 ? 118 VAL B O   1 
ATOM   7057  C  CB  . VAL B 1 118 ? 185.853 229.593 299.291 1.00 150.40 ? 118 VAL B CB  1 
ATOM   7058  C  CG1 . VAL B 1 118 ? 185.690 228.726 298.068 1.00 146.46 ? 118 VAL B CG1 1 
ATOM   7059  C  CG2 . VAL B 1 118 ? 186.804 228.939 300.278 1.00 149.55 ? 118 VAL B CG2 1 
ATOM   7060  N  N   . SER B 1 119 ? 185.144 232.536 300.265 1.00 155.49 ? 119 SER B N   1 
ATOM   7061  C  CA  . SER B 1 119 ? 184.891 233.423 301.391 1.00 154.31 ? 119 SER B CA  1 
ATOM   7062  C  C   . SER B 1 119 ? 183.626 232.971 302.104 1.00 157.33 ? 119 SER B C   1 
ATOM   7063  O  O   . SER B 1 119 ? 182.568 232.847 301.478 1.00 156.39 ? 119 SER B O   1 
ATOM   7064  C  CB  . SER B 1 119 ? 184.753 234.879 300.933 1.00 151.00 ? 119 SER B CB  1 
ATOM   7065  O  OG  . SER B 1 119 ? 184.574 235.746 302.039 1.00 150.82 ? 119 SER B OG  1 
ATOM   7066  N  N   . ALA B 1 120 ? 183.737 232.730 303.408 1.00 158.37 ? 120 ALA B N   1 
ATOM   7067  C  CA  . ALA B 1 120 ? 182.602 232.308 304.214 1.00 159.32 ? 120 ALA B CA  1 
ATOM   7068  C  C   . ALA B 1 120 ? 182.890 232.633 305.671 1.00 161.68 ? 120 ALA B C   1 
ATOM   7069  O  O   . ALA B 1 120 ? 184.035 232.545 306.124 1.00 161.10 ? 120 ALA B O   1 
ATOM   7070  C  CB  . ALA B 1 120 ? 182.311 230.813 304.045 1.00 156.07 ? 120 ALA B CB  1 
ATOM   7071  N  N   . GLU B 1 121 ? 181.835 233.016 306.394 1.00 161.59 ? 121 GLU B N   1 
ATOM   7072  C  CA  . GLU B 1 121 ? 181.926 233.381 307.809 1.00 160.15 ? 121 GLU B CA  1 
ATOM   7073  C  C   . GLU B 1 121 ? 182.933 234.506 308.039 1.00 161.53 ? 121 GLU B C   1 
ATOM   7074  O  O   . GLU B 1 121 ? 183.571 234.578 309.093 1.00 159.68 ? 121 GLU B O   1 
ATOM   7075  C  CB  . GLU B 1 121 ? 182.274 232.169 308.679 1.00 159.54 ? 121 GLU B CB  1 
ATOM   7076  C  CG  . GLU B 1 121 ? 181.336 230.985 308.503 1.00 161.64 ? 121 GLU B CG  1 
ATOM   7077  C  CD  . GLU B 1 121 ? 181.889 229.940 307.553 1.00 164.24 ? 121 GLU B CD  1 
ATOM   7078  O  OE1 . GLU B 1 121 ? 183.118 229.719 307.561 1.00 164.77 ? 121 GLU B OE1 1 
ATOM   7079  O  OE2 . GLU B 1 121 ? 181.094 229.339 306.800 1.00 165.05 ? 121 GLU B OE2 1 
ATOM   7080  N  N   . GLY B 1 122 ? 183.083 235.390 307.056 1.00 162.76 ? 122 GLY B N   1 
ATOM   7081  C  CA  . GLY B 1 122 ? 184.042 236.470 307.167 1.00 158.65 ? 122 GLY B CA  1 
ATOM   7082  C  C   . GLY B 1 122 ? 185.488 236.047 307.068 1.00 158.03 ? 122 GLY B C   1 
ATOM   7083  O  O   . GLY B 1 122 ? 186.375 236.816 307.447 1.00 154.40 ? 122 GLY B O   1 
ATOM   7084  N  N   . LYS B 1 123 ? 185.756 234.843 306.567 1.00 159.82 ? 123 LYS B N   1 
ATOM   7085  C  CA  . LYS B 1 123 ? 187.111 234.329 306.446 1.00 156.81 ? 123 LYS B CA  1 
ATOM   7086  C  C   . LYS B 1 123 ? 187.314 233.745 305.055 1.00 153.32 ? 123 LYS B C   1 
ATOM   7087  O  O   . LYS B 1 123 ? 186.394 233.193 304.447 1.00 151.47 ? 123 LYS B O   1 
ATOM   7088  C  CB  . LYS B 1 123 ? 187.407 233.265 307.513 1.00 155.40 ? 123 LYS B CB  1 
ATOM   7089  C  CG  . LYS B 1 123 ? 187.306 233.770 308.943 1.00 154.33 ? 123 LYS B CG  1 
ATOM   7090  C  CD  . LYS B 1 123 ? 187.124 232.621 309.922 1.00 152.68 ? 123 LYS B CD  1 
ATOM   7091  C  CE  . LYS B 1 123 ? 187.181 233.106 311.362 1.00 146.00 ? 123 LYS B CE  1 
ATOM   7092  N  NZ  . LYS B 1 123 ? 187.160 231.975 312.330 1.00 147.61 ? 123 LYS B NZ  1 
ATOM   7093  N  N   . VAL B 1 124 ? 188.544 233.857 304.562 1.00 151.52 ? 124 VAL B N   1 
ATOM   7094  C  CA  . VAL B 1 124 ? 188.904 233.418 303.220 1.00 150.05 ? 124 VAL B CA  1 
ATOM   7095  C  C   . VAL B 1 124 ? 189.710 232.133 303.331 1.00 148.73 ? 124 VAL B C   1 
ATOM   7096  O  O   . VAL B 1 124 ? 190.693 232.070 304.077 1.00 148.07 ? 124 VAL B O   1 
ATOM   7097  C  CB  . VAL B 1 124 ? 189.695 234.500 302.465 1.00 147.88 ? 124 VAL B CB  1 
ATOM   7098  C  CG1 . VAL B 1 124 ? 190.153 233.976 301.114 1.00 147.13 ? 124 VAL B CG1 1 
ATOM   7099  C  CG2 . VAL B 1 124 ? 188.849 235.752 302.299 1.00 146.39 ? 124 VAL B CG2 1 
ATOM   7100  N  N   . TYR B 1 125 ? 189.290 231.113 302.595 1.00 147.61 ? 125 TYR B N   1 
ATOM   7101  C  CA  . TYR B 1 125 ? 189.960 229.823 302.561 1.00 148.51 ? 125 TYR B CA  1 
ATOM   7102  C  C   . TYR B 1 125 ? 190.359 229.487 301.131 1.00 144.64 ? 125 TYR B C   1 
ATOM   7103  O  O   . TYR B 1 125 ? 189.884 230.091 300.167 1.00 139.99 ? 125 TYR B O   1 
ATOM   7104  C  CB  . TYR B 1 125 ? 189.067 228.723 303.145 1.00 149.77 ? 125 TYR B CB  1 
ATOM   7105  C  CG  . TYR B 1 125 ? 188.221 229.181 304.309 1.00 151.79 ? 125 TYR B CG  1 
ATOM   7106  C  CD1 . TYR B 1 125 ? 188.780 229.366 305.566 1.00 151.47 ? 125 TYR B CD1 1 
ATOM   7107  C  CD2 . TYR B 1 125 ? 186.865 229.432 304.151 1.00 152.70 ? 125 TYR B CD2 1 
ATOM   7108  C  CE1 . TYR B 1 125 ? 188.010 229.784 306.635 1.00 153.42 ? 125 TYR B CE1 1 
ATOM   7109  C  CE2 . TYR B 1 125 ? 186.087 229.851 305.212 1.00 156.07 ? 125 TYR B CE2 1 
ATOM   7110  C  CZ  . TYR B 1 125 ? 186.664 230.025 306.452 1.00 156.28 ? 125 TYR B CZ  1 
ATOM   7111  O  OH  . TYR B 1 125 ? 185.892 230.441 307.512 1.00 156.18 ? 125 TYR B OH  1 
ATOM   7112  N  N   . TYR B 1 126 ? 191.256 228.515 301.002 1.00 145.78 ? 126 TYR B N   1 
ATOM   7113  C  CA  . TYR B 1 126 ? 191.793 228.151 299.701 1.00 145.28 ? 126 TYR B CA  1 
ATOM   7114  C  C   . TYR B 1 126 ? 191.861 226.638 299.563 1.00 144.03 ? 126 TYR B C   1 
ATOM   7115  O  O   . TYR B 1 126 ? 192.078 225.921 300.545 1.00 144.46 ? 126 TYR B O   1 
ATOM   7116  C  CB  . TYR B 1 126 ? 193.183 228.759 299.487 1.00 146.77 ? 126 TYR B CB  1 
ATOM   7117  C  CG  . TYR B 1 126 ? 193.203 230.269 299.481 1.00 148.99 ? 126 TYR B CG  1 
ATOM   7118  C  CD1 . TYR B 1 126 ? 193.368 230.985 300.659 1.00 149.57 ? 126 TYR B CD1 1 
ATOM   7119  C  CD2 . TYR B 1 126 ? 193.065 230.980 298.297 1.00 147.35 ? 126 TYR B CD2 1 
ATOM   7120  C  CE1 . TYR B 1 126 ? 193.390 232.367 300.659 1.00 149.36 ? 126 TYR B CE1 1 
ATOM   7121  C  CE2 . TYR B 1 126 ? 193.087 232.361 298.287 1.00 146.22 ? 126 TYR B CE2 1 
ATOM   7122  C  CZ  . TYR B 1 126 ? 193.249 233.050 299.471 1.00 148.41 ? 126 TYR B CZ  1 
ATOM   7123  O  OH  . TYR B 1 126 ? 193.271 234.425 299.465 1.00 145.87 ? 126 TYR B OH  1 
ATOM   7124  N  N   . LEU B 1 127 ? 191.671 226.163 298.334 1.00 142.08 ? 127 LEU B N   1 
ATOM   7125  C  CA  . LEU B 1 127 ? 191.756 224.745 298.007 1.00 142.20 ? 127 LEU B CA  1 
ATOM   7126  C  C   . LEU B 1 127 ? 192.656 224.565 296.794 1.00 138.03 ? 127 LEU B C   1 
ATOM   7127  O  O   . LEU B 1 127 ? 192.504 225.270 295.791 1.00 133.81 ? 127 LEU B O   1 
ATOM   7128  C  CB  . LEU B 1 127 ? 190.368 224.151 297.738 1.00 143.37 ? 127 LEU B CB  1 
ATOM   7129  C  CG  . LEU B 1 127 ? 190.315 222.681 297.320 1.00 141.36 ? 127 LEU B CG  1 
ATOM   7130  C  CD1 . LEU B 1 127 ? 190.597 221.772 298.506 1.00 141.55 ? 127 LEU B CD1 1 
ATOM   7131  C  CD2 . LEU B 1 127 ? 188.967 222.351 296.697 1.00 138.16 ? 127 LEU B CD2 1 
ATOM   7132  N  N   . ALA B 1 128 ? 193.589 223.623 296.887 1.00 136.99 ? 128 ALA B N   1 
ATOM   7133  C  CA  . ALA B 1 128 ? 194.567 223.372 295.842 1.00 131.86 ? 128 ALA B CA  1 
ATOM   7134  C  C   . ALA B 1 128 ? 194.440 221.945 295.331 1.00 128.08 ? 128 ALA B C   1 
ATOM   7135  O  O   . ALA B 1 128 ? 194.393 220.992 296.115 1.00 131.24 ? 128 ALA B O   1 
ATOM   7136  C  CB  . ALA B 1 128 ? 195.989 223.617 296.349 1.00 130.13 ? 128 ALA B CB  1 
ATOM   7137  N  N   . LEU B 1 129 ? 194.395 221.818 294.009 1.00 120.64 ? 129 LEU B N   1 
ATOM   7138  C  CA  . LEU B 1 129 ? 194.293 220.546 293.311 1.00 118.01 ? 129 LEU B CA  1 
ATOM   7139  C  C   . LEU B 1 129 ? 195.623 220.253 292.638 1.00 109.49 ? 129 LEU B C   1 
ATOM   7140  O  O   . LEU B 1 129 ? 196.216 221.140 292.022 1.00 107.71 ? 129 LEU B O   1 
ATOM   7141  C  CB  . LEU B 1 129 ? 193.168 220.587 292.278 1.00 124.33 ? 129 LEU B CB  1 
ATOM   7142  C  CG  . LEU B 1 129 ? 191.882 221.288 292.721 1.00 128.91 ? 129 LEU B CG  1 
ATOM   7143  C  CD1 . LEU B 1 129 ? 190.890 221.386 291.571 1.00 131.44 ? 129 LEU B CD1 1 
ATOM   7144  C  CD2 . LEU B 1 129 ? 191.260 220.566 293.907 1.00 132.10 ? 129 LEU B CD2 1 
ATOM   7145  N  N   . VAL B 1 130 ? 196.084 219.016 292.758 1.00 106.37 ? 130 VAL B N   1 
ATOM   7146  C  CA  . VAL B 1 130 ? 197.428 218.630 292.352 1.00 107.21 ? 130 VAL B CA  1 
ATOM   7147  C  C   . VAL B 1 130 ? 197.338 217.422 291.432 1.00 108.72 ? 130 VAL B C   1 
ATOM   7148  O  O   . VAL B 1 130 ? 196.585 216.480 291.710 1.00 118.89 ? 130 VAL B O   1 
ATOM   7149  C  CB  . VAL B 1 130 ? 198.313 218.316 293.574 1.00 116.79 ? 130 VAL B CB  1 
ATOM   7150  C  CG1 . VAL B 1 130 ? 199.712 217.926 293.138 1.00 119.19 ? 130 VAL B CG1 1 
ATOM   7151  C  CG2 . VAL B 1 130 ? 198.358 219.506 294.520 1.00 120.23 ? 130 VAL B CG2 1 
ATOM   7152  N  N   . ARG B 1 131 ? 198.107 217.449 290.346 1.00 97.28  ? 131 ARG B N   1 
ATOM   7153  C  CA  . ARG B 1 131 ? 198.166 216.371 289.373 1.00 93.15  ? 131 ARG B CA  1 
ATOM   7154  C  C   . ARG B 1 131 ? 199.605 215.965 289.101 1.00 91.04  ? 131 ARG B C   1 
ATOM   7155  O  O   . ARG B 1 131 ? 200.509 216.803 289.064 1.00 94.80  ? 131 ARG B O   1 
ATOM   7156  C  CB  . ARG B 1 131 ? 197.494 216.773 288.058 1.00 98.95  ? 131 ARG B CB  1 
ATOM   7157  C  CG  . ARG B 1 131 ? 196.006 217.126 288.131 1.00 105.38 ? 131 ARG B CG  1 
ATOM   7158  C  CD  . ARG B 1 131 ? 195.076 216.091 288.803 1.00 113.54 ? 131 ARG B CD  1 
ATOM   7159  N  NE  . ARG B 1 131 ? 195.677 214.801 289.129 1.00 115.69 ? 131 ARG B NE  1 
ATOM   7160  C  CZ  . ARG B 1 131 ? 195.857 213.815 288.261 1.00 114.56 ? 131 ARG B CZ  1 
ATOM   7161  N  NH1 . ARG B 1 131 ? 195.516 213.941 286.989 1.00 113.49 ? 131 ARG B NH1 1 
ATOM   7162  N  NH2 . ARG B 1 131 ? 196.400 212.675 288.678 1.00 113.19 ? 131 ARG B NH2 1 
ATOM   7163  N  N   . ASP B 1 132 ? 199.795 214.669 288.870 1.00 95.13  ? 132 ASP B N   1 
ATOM   7164  C  CA  . ASP B 1 132 ? 201.128 214.091 288.756 1.00 102.46 ? 132 ASP B CA  1 
ATOM   7165  C  C   . ASP B 1 132 ? 201.893 214.552 287.521 1.00 99.36  ? 132 ASP B C   1 
ATOM   7166  O  O   . ASP B 1 132 ? 203.103 214.315 287.451 1.00 104.16 ? 132 ASP B O   1 
ATOM   7167  C  CB  . ASP B 1 132 ? 201.038 212.563 288.758 1.00 109.16 ? 132 ASP B CB  1 
ATOM   7168  C  CG  . ASP B 1 132 ? 200.149 212.033 289.867 1.00 116.97 ? 132 ASP B CG  1 
ATOM   7169  O  OD1 . ASP B 1 132 ? 199.989 212.731 290.890 1.00 121.18 ? 132 ASP B OD1 1 
ATOM   7170  O  OD2 . ASP B 1 132 ? 199.619 210.911 289.720 1.00 116.70 ? 132 ASP B OD2 1 
ATOM   7171  N  N   . ALA B 1 133 ? 201.231 215.183 286.550 1.00 90.18  ? 133 ALA B N   1 
ATOM   7172  C  CA  . ALA B 1 133 ? 201.888 215.709 285.353 1.00 79.98  ? 133 ALA B CA  1 
ATOM   7173  C  C   . ALA B 1 133 ? 202.628 214.602 284.598 1.00 72.47  ? 133 ALA B C   1 
ATOM   7174  O  O   . ALA B 1 133 ? 203.856 214.552 284.538 1.00 70.03  ? 133 ALA B O   1 
ATOM   7175  C  CB  . ALA B 1 133 ? 202.836 216.859 285.699 1.00 88.37  ? 133 ALA B CB  1 
ATOM   7176  N  N   . SER B 1 134 ? 201.837 213.690 284.051 1.00 75.63  ? 134 SER B N   1 
ATOM   7177  C  CA  . SER B 1 134 ? 202.341 212.713 283.097 1.00 78.46  ? 134 SER B CA  1 
ATOM   7178  C  C   . SER B 1 134 ? 202.396 213.258 281.677 1.00 72.53  ? 134 SER B C   1 
ATOM   7179  O  O   . SER B 1 134 ? 202.812 212.536 280.767 1.00 69.56  ? 134 SER B O   1 
ATOM   7180  C  CB  . SER B 1 134 ? 201.480 211.448 283.125 1.00 80.60  ? 134 SER B CB  1 
ATOM   7181  O  OG  . SER B 1 134 ? 201.791 210.609 282.026 1.00 82.01  ? 134 SER B OG  1 
ATOM   7182  N  N   . VAL B 1 135 ? 201.967 214.503 281.466 1.00 65.77  ? 135 VAL B N   1 
ATOM   7183  C  CA  . VAL B 1 135 ? 202.010 215.093 280.137 1.00 61.43  ? 135 VAL B CA  1 
ATOM   7184  C  C   . VAL B 1 135 ? 203.317 215.817 279.876 1.00 61.47  ? 135 VAL B C   1 
ATOM   7185  O  O   . VAL B 1 135 ? 203.624 216.120 278.721 1.00 64.71  ? 135 VAL B O   1 
ATOM   7186  C  CB  . VAL B 1 135 ? 200.837 216.063 279.938 1.00 66.45  ? 135 VAL B CB  1 
ATOM   7187  C  CG1 . VAL B 1 135 ? 199.561 215.466 280.503 1.00 69.21  ? 135 VAL B CG1 1 
ATOM   7188  C  CG2 . VAL B 1 135 ? 201.137 217.398 280.591 1.00 65.80  ? 135 VAL B CG2 1 
ATOM   7189  N  N   . GLU B 1 136 ? 204.089 216.123 280.916 1.00 61.41  ? 136 GLU B N   1 
ATOM   7190  C  CA  . GLU B 1 136 ? 205.369 216.778 280.693 1.00 60.74  ? 136 GLU B CA  1 
ATOM   7191  C  C   . GLU B 1 136 ? 206.325 215.866 279.953 1.00 56.65  ? 136 GLU B C   1 
ATOM   7192  O  O   . GLU B 1 136 ? 207.140 216.338 279.159 1.00 60.33  ? 136 GLU B O   1 
ATOM   7193  C  CB  . GLU B 1 136 ? 205.979 217.222 282.016 1.00 77.32  ? 136 GLU B CB  1 
ATOM   7194  C  CG  . GLU B 1 136 ? 206.815 218.480 281.909 1.00 92.56  ? 136 GLU B CG  1 
ATOM   7195  C  CD  . GLU B 1 136 ? 205.969 219.726 281.757 1.00 99.74  ? 136 GLU B CD  1 
ATOM   7196  O  OE1 . GLU B 1 136 ? 206.379 220.637 281.008 1.00 98.15  ? 136 GLU B OE1 1 
ATOM   7197  O  OE2 . GLU B 1 136 ? 204.890 219.792 282.382 1.00 103.41 ? 136 GLU B OE2 1 
ATOM   7198  N  N   . MET B 1 137 ? 206.243 214.563 280.203 1.00 52.28  ? 137 MET B N   1 
ATOM   7199  C  CA  . MET B 1 137 ? 207.039 213.626 279.430 1.00 54.80  ? 137 MET B CA  1 
ATOM   7200  C  C   . MET B 1 137 ? 206.684 213.734 277.958 1.00 59.92  ? 137 MET B C   1 
ATOM   7201  O  O   . MET B 1 137 ? 207.571 213.761 277.100 1.00 60.89  ? 137 MET B O   1 
ATOM   7202  C  CB  . MET B 1 137 ? 206.810 212.206 279.944 1.00 59.65  ? 137 MET B CB  1 
ATOM   7203  C  CG  . MET B 1 137 ? 207.521 211.087 279.182 1.00 64.86  ? 137 MET B CG  1 
ATOM   7204  S  SD  . MET B 1 137 ? 209.110 211.520 278.444 1.00 75.35  ? 137 MET B SD  1 
ATOM   7205  C  CE  . MET B 1 137 ? 209.105 210.485 276.982 1.00 57.14  ? 137 MET B CE  1 
ATOM   7206  N  N   . ALA B 1 138 ? 205.389 213.837 277.648 1.00 65.30  ? 138 ALA B N   1 
ATOM   7207  C  CA  . ALA B 1 138 ? 204.971 213.990 276.259 1.00 63.00  ? 138 ALA B CA  1 
ATOM   7208  C  C   . ALA B 1 138 ? 205.467 215.303 275.672 1.00 56.74  ? 138 ALA B C   1 
ATOM   7209  O  O   . ALA B 1 138 ? 205.960 215.334 274.541 1.00 57.26  ? 138 ALA B O   1 
ATOM   7210  C  CB  . ALA B 1 138 ? 203.451 213.895 276.144 1.00 57.46  ? 138 ALA B CB  1 
ATOM   7211  N  N   . GLN B 1 139 ? 205.350 216.399 276.420 1.00 54.79  ? 139 GLN B N   1 
ATOM   7212  C  CA  . GLN B 1 139 ? 205.811 217.681 275.899 1.00 52.47  ? 139 GLN B CA  1 
ATOM   7213  C  C   . GLN B 1 139 ? 207.298 217.643 275.601 1.00 51.52  ? 139 GLN B C   1 
ATOM   7214  O  O   . GLN B 1 139 ? 207.743 218.104 274.544 1.00 56.07  ? 139 GLN B O   1 
ATOM   7215  C  CB  . GLN B 1 139 ? 205.512 218.798 276.891 1.00 58.64  ? 139 GLN B CB  1 
ATOM   7216  C  CG  . GLN B 1 139 ? 204.119 219.363 276.809 1.00 63.66  ? 139 GLN B CG  1 
ATOM   7217  C  CD  . GLN B 1 139 ? 204.108 220.856 277.028 1.00 72.96  ? 139 GLN B CD  1 
ATOM   7218  O  OE1 . GLN B 1 139 ? 205.158 221.477 277.164 1.00 74.59  ? 139 GLN B OE1 1 
ATOM   7219  N  NE2 . GLN B 1 139 ? 202.920 221.442 277.065 1.00 78.41  ? 139 GLN B NE2 1 
ATOM   7220  N  N   . LYS B 1 140 ? 208.084 217.087 276.516 1.00 51.00  ? 140 LYS B N   1 
ATOM   7221  C  CA  . LYS B 1 140 ? 209.524 217.102 276.329 1.00 51.71  ? 140 LYS B CA  1 
ATOM   7222  C  C   . LYS B 1 140 ? 209.923 216.151 275.206 1.00 54.63  ? 140 LYS B C   1 
ATOM   7223  O  O   . LYS B 1 140 ? 210.810 216.467 274.403 1.00 58.80  ? 140 LYS B O   1 
ATOM   7224  C  CB  . LYS B 1 140 ? 210.212 216.760 277.651 1.00 50.14  ? 140 LYS B CB  1 
ATOM   7225  C  CG  . LYS B 1 140 ? 211.739 216.608 277.656 1.00 52.35  ? 140 LYS B CG  1 
ATOM   7226  C  CD  . LYS B 1 140 ? 212.517 217.511 276.676 1.00 55.39  ? 140 LYS B CD  1 
ATOM   7227  C  CE  . LYS B 1 140 ? 212.332 219.010 276.937 1.00 55.60  ? 140 LYS B CE  1 
ATOM   7228  N  NZ  . LYS B 1 140 ? 213.046 219.850 275.926 1.00 47.97  ? 140 LYS B NZ  1 
ATOM   7229  N  N   . GLU B 1 141 ? 209.260 214.997 275.103 1.00 50.63  ? 141 GLU B N   1 
ATOM   7230  C  CA  . GLU B 1 141 ? 209.576 214.089 274.010 1.00 51.66  ? 141 GLU B CA  1 
ATOM   7231  C  C   . GLU B 1 141 ? 209.225 214.719 272.672 1.00 54.41  ? 141 GLU B C   1 
ATOM   7232  O  O   . GLU B 1 141 ? 209.975 214.585 271.692 1.00 58.05  ? 141 GLU B O   1 
ATOM   7233  C  CB  . GLU B 1 141 ? 208.865 212.746 274.209 1.00 57.30  ? 141 GLU B CB  1 
ATOM   7234  C  CG  . GLU B 1 141 ? 207.405 212.714 273.787 1.00 64.03  ? 141 GLU B CG  1 
ATOM   7235  C  CD  . GLU B 1 141 ? 206.703 211.416 274.142 1.00 71.58  ? 141 GLU B CD  1 
ATOM   7236  O  OE1 . GLU B 1 141 ? 206.380 210.642 273.216 1.00 73.44  ? 141 GLU B OE1 1 
ATOM   7237  O  OE2 . GLU B 1 141 ? 206.458 211.176 275.341 1.00 70.94  ? 141 GLU B OE2 1 
ATOM   7238  N  N   . GLN B 1 142 ? 208.110 215.449 272.623 1.00 53.09  ? 142 GLN B N   1 
ATOM   7239  C  CA  . GLN B 1 142 ? 207.717 216.110 271.391 1.00 48.09  ? 142 GLN B CA  1 
ATOM   7240  C  C   . GLN B 1 142 ? 208.727 217.174 271.025 1.00 44.96  ? 142 GLN B C   1 
ATOM   7241  O  O   . GLN B 1 142 ? 209.042 217.358 269.849 1.00 49.98  ? 142 GLN B O   1 
ATOM   7242  C  CB  . GLN B 1 142 ? 206.293 216.664 271.542 1.00 49.55  ? 142 GLN B CB  1 
ATOM   7243  C  CG  . GLN B 1 142 ? 205.745 217.680 270.526 1.00 53.29  ? 142 GLN B CG  1 
ATOM   7244  C  CD  . GLN B 1 142 ? 206.515 218.972 270.368 1.00 56.44  ? 142 GLN B CD  1 
ATOM   7245  O  OE1 . GLN B 1 142 ? 207.169 219.442 271.297 1.00 57.69  ? 142 GLN B OE1 1 
ATOM   7246  N  NE2 . GLN B 1 142 ? 206.437 219.558 269.182 1.00 58.65  ? 142 GLN B NE2 1 
ATOM   7247  N  N   . THR B 1 143 ? 209.245 217.889 272.021 1.00 45.54  ? 143 THR B N   1 
ATOM   7248  C  CA  . THR B 1 143 ? 210.265 218.893 271.747 1.00 47.92  ? 143 THR B CA  1 
ATOM   7249  C  C   . THR B 1 143 ? 211.543 218.250 271.231 1.00 45.30  ? 143 THR B C   1 
ATOM   7250  O  O   . THR B 1 143 ? 212.200 218.795 270.339 1.00 50.72  ? 143 THR B O   1 
ATOM   7251  C  CB  . THR B 1 143 ? 210.528 219.731 272.999 1.00 54.59  ? 143 THR B CB  1 
ATOM   7252  O  OG1 . THR B 1 143 ? 209.464 220.675 273.169 1.00 51.97  ? 143 THR B OG1 1 
ATOM   7253  C  CG2 . THR B 1 143 ? 211.840 220.490 272.887 1.00 55.56  ? 143 THR B CG2 1 
ATOM   7254  N  N   . ARG B 1 144 ? 211.907 217.082 271.758 1.00 43.62  ? 144 ARG B N   1 
ATOM   7255  C  CA  . ARG B 1 144 ? 213.106 216.417 271.253 1.00 50.17  ? 144 ARG B CA  1 
ATOM   7256  C  C   . ARG B 1 144 ? 212.949 216.028 269.789 1.00 52.88  ? 144 ARG B C   1 
ATOM   7257  O  O   . ARG B 1 144 ? 213.841 216.275 268.964 1.00 55.17  ? 144 ARG B O   1 
ATOM   7258  C  CB  . ARG B 1 144 ? 213.450 215.183 272.081 1.00 57.67  ? 144 ARG B CB  1 
ATOM   7259  C  CG  . ARG B 1 144 ? 213.642 215.416 273.552 1.00 60.29  ? 144 ARG B CG  1 
ATOM   7260  C  CD  . ARG B 1 144 ? 213.071 214.268 274.351 1.00 58.91  ? 144 ARG B CD  1 
ATOM   7261  N  NE  . ARG B 1 144 ? 213.235 214.473 275.782 1.00 62.99  ? 144 ARG B NE  1 
ATOM   7262  C  CZ  . ARG B 1 144 ? 214.399 214.438 276.415 1.00 68.19  ? 144 ARG B CZ  1 
ATOM   7263  N  NH1 . ARG B 1 144 ? 215.526 214.177 275.775 1.00 75.02  ? 144 ARG B NH1 1 
ATOM   7264  N  NH2 . ARG B 1 144 ? 214.433 214.669 277.724 1.00 64.32  ? 144 ARG B NH2 1 
ATOM   7265  N  N   . GLN B 1 145 ? 211.813 215.430 269.436 1.00 52.97  ? 145 GLN B N   1 
ATOM   7266  C  CA  . GLN B 1 145 ? 211.666 215.048 268.037 1.00 49.27  ? 145 GLN B CA  1 
ATOM   7267  C  C   . GLN B 1 145 ? 211.355 216.236 267.136 1.00 52.33  ? 145 GLN B C   1 
ATOM   7268  O  O   . GLN B 1 145 ? 211.538 216.135 265.919 1.00 56.79  ? 145 GLN B O   1 
ATOM   7269  C  CB  . GLN B 1 145 ? 210.618 213.951 267.867 1.00 45.40  ? 145 GLN B CB  1 
ATOM   7270  C  CG  . GLN B 1 145 ? 209.434 214.068 268.764 1.00 48.01  ? 145 GLN B CG  1 
ATOM   7271  C  CD  . GLN B 1 145 ? 208.734 212.753 268.925 1.00 51.89  ? 145 GLN B CD  1 
ATOM   7272  O  OE1 . GLN B 1 145 ? 207.712 212.502 268.291 1.00 58.31  ? 145 GLN B OE1 1 
ATOM   7273  N  NE2 . GLN B 1 145 ? 209.284 211.891 269.763 1.00 52.19  ? 145 GLN B NE2 1 
ATOM   7274  N  N   . LEU B 1 146 ? 210.906 217.359 267.699 1.00 52.36  ? 146 LEU B N   1 
ATOM   7275  C  CA  . LEU B 1 146 ? 210.839 218.602 266.943 1.00 45.51  ? 146 LEU B CA  1 
ATOM   7276  C  C   . LEU B 1 146 ? 212.223 219.161 266.689 1.00 44.99  ? 146 LEU B C   1 
ATOM   7277  O  O   . LEU B 1 146 ? 212.447 219.821 265.674 1.00 47.41  ? 146 LEU B O   1 
ATOM   7278  C  CB  . LEU B 1 146 ? 209.994 219.628 267.692 1.00 46.13  ? 146 LEU B CB  1 
ATOM   7279  C  CG  . LEU B 1 146 ? 209.210 220.605 266.827 1.00 46.48  ? 146 LEU B CG  1 
ATOM   7280  C  CD1 . LEU B 1 146 ? 208.222 219.866 265.960 1.00 45.39  ? 146 LEU B CD1 1 
ATOM   7281  C  CD2 . LEU B 1 146 ? 208.501 221.610 267.707 1.00 51.03  ? 146 LEU B CD2 1 
ATOM   7282  N  N   . ILE B 1 147 ? 213.146 218.930 267.621 1.00 49.24  ? 147 ILE B N   1 
ATOM   7283  C  CA  . ILE B 1 147 ? 214.543 219.277 267.392 1.00 52.25  ? 147 ILE B CA  1 
ATOM   7284  C  C   . ILE B 1 147 ? 215.101 218.454 266.246 1.00 54.16  ? 147 ILE B C   1 
ATOM   7285  O  O   . ILE B 1 147 ? 215.710 218.989 265.312 1.00 59.89  ? 147 ILE B O   1 
ATOM   7286  C  CB  . ILE B 1 147 ? 215.371 219.069 268.673 1.00 49.72  ? 147 ILE B CB  1 
ATOM   7287  C  CG1 . ILE B 1 147 ? 215.319 220.312 269.563 1.00 49.25  ? 147 ILE B CG1 1 
ATOM   7288  C  CG2 . ILE B 1 147 ? 216.812 218.706 268.332 1.00 47.43  ? 147 ILE B CG2 1 
ATOM   7289  C  CD1 . ILE B 1 147 ? 215.800 220.067 270.979 1.00 50.52  ? 147 ILE B CD1 1 
ATOM   7290  N  N   . ILE B 1 148 ? 214.891 217.138 266.287 1.00 50.88  ? 148 ILE B N   1 
ATOM   7291  C  CA  . ILE B 1 148 ? 215.640 216.307 265.354 1.00 49.69  ? 148 ILE B CA  1 
ATOM   7292  C  C   . ILE B 1 148 ? 215.020 216.324 263.958 1.00 48.73  ? 148 ILE B C   1 
ATOM   7293  O  O   . ILE B 1 148 ? 215.733 216.123 262.968 1.00 54.39  ? 148 ILE B O   1 
ATOM   7294  C  CB  . ILE B 1 148 ? 215.768 214.882 265.899 1.00 51.99  ? 148 ILE B CB  1 
ATOM   7295  C  CG1 . ILE B 1 148 ? 216.235 213.957 264.813 1.00 49.61  ? 148 ILE B CG1 1 
ATOM   7296  C  CG2 . ILE B 1 148 ? 214.452 214.385 266.361 1.00 53.87  ? 148 ILE B CG2 1 
ATOM   7297  C  CD1 . ILE B 1 148 ? 217.665 214.294 264.478 1.00 52.29  ? 148 ILE B CD1 1 
ATOM   7298  N  N   . ALA B 1 149 ? 213.722 216.626 263.834 1.00 47.56  ? 149 ALA B N   1 
ATOM   7299  C  CA  . ALA B 1 149 ? 213.130 216.772 262.506 1.00 44.34  ? 149 ALA B CA  1 
ATOM   7300  C  C   . ALA B 1 149 ? 213.813 217.860 261.702 1.00 54.66  ? 149 ALA B C   1 
ATOM   7301  O  O   . ALA B 1 149 ? 213.687 217.877 260.474 1.00 64.39  ? 149 ALA B O   1 
ATOM   7302  C  CB  . ALA B 1 149 ? 211.639 217.090 262.592 1.00 29.95  ? 149 ALA B CB  1 
ATOM   7303  N  N   . VAL B 1 150 ? 214.530 218.772 262.362 1.00 51.45  ? 150 VAL B N   1 
ATOM   7304  C  CA  . VAL B 1 150 ? 215.149 219.904 261.697 1.00 52.69  ? 150 VAL B CA  1 
ATOM   7305  C  C   . VAL B 1 150 ? 216.668 219.890 261.812 1.00 57.49  ? 150 VAL B C   1 
ATOM   7306  O  O   . VAL B 1 150 ? 217.362 220.307 260.880 1.00 62.71  ? 150 VAL B O   1 
ATOM   7307  C  CB  . VAL B 1 150 ? 214.574 221.235 262.231 1.00 58.27  ? 150 VAL B CB  1 
ATOM   7308  C  CG1 . VAL B 1 150 ? 213.068 221.136 262.373 1.00 56.56  ? 150 VAL B CG1 1 
ATOM   7309  C  CG2 . VAL B 1 150 ? 215.200 221.618 263.562 1.00 59.22  ? 150 VAL B CG2 1 
ATOM   7310  N  N   . ASP B 1 151 ? 217.213 219.394 262.918 1.00 61.02  ? 151 ASP B N   1 
ATOM   7311  C  CA  . ASP B 1 151 ? 218.586 219.726 263.282 1.00 65.85  ? 151 ASP B CA  1 
ATOM   7312  C  C   . ASP B 1 151 ? 219.568 218.859 262.503 1.00 70.28  ? 151 ASP B C   1 
ATOM   7313  O  O   . ASP B 1 151 ? 219.451 217.631 262.482 1.00 67.87  ? 151 ASP B O   1 
ATOM   7314  C  CB  . ASP B 1 151 ? 218.785 219.573 264.793 1.00 68.98  ? 151 ASP B CB  1 
ATOM   7315  C  CG  . ASP B 1 151 ? 220.247 219.714 265.241 1.00 74.53  ? 151 ASP B CG  1 
ATOM   7316  O  OD1 . ASP B 1 151 ? 221.176 219.173 264.607 1.00 74.44  ? 151 ASP B OD1 1 
ATOM   7317  O  OD2 . ASP B 1 151 ? 220.466 220.394 266.266 1.00 75.62  ? 151 ASP B OD2 1 
ATOM   7318  N  N   . HIS B 1 152 ? 220.547 219.518 261.881 1.00 77.30  ? 152 HIS B N   1 
ATOM   7319  C  CA  . HIS B 1 152 ? 221.595 218.867 261.091 1.00 86.25  ? 152 HIS B CA  1 
ATOM   7320  C  C   . HIS B 1 152 ? 221.010 217.944 260.030 1.00 80.17  ? 152 HIS B C   1 
ATOM   7321  O  O   . HIS B 1 152 ? 221.571 216.889 259.726 1.00 81.00  ? 152 HIS B O   1 
ATOM   7322  C  CB  . HIS B 1 152 ? 222.583 218.107 261.980 1.00 86.74  ? 152 HIS B CB  1 
ATOM   7323  C  CG  . HIS B 1 152 ? 223.960 218.014 261.399 1.00 92.08  ? 152 HIS B CG  1 
ATOM   7324  N  ND1 . HIS B 1 152 ? 224.833 219.081 261.381 1.00 93.44  ? 152 HIS B ND1 1 
ATOM   7325  C  CD2 . HIS B 1 152 ? 224.612 216.985 260.808 1.00 88.18  ? 152 HIS B CD2 1 
ATOM   7326  C  CE1 . HIS B 1 152 ? 225.963 218.712 260.806 1.00 92.33  ? 152 HIS B CE1 1 
ATOM   7327  N  NE2 . HIS B 1 152 ? 225.856 217.445 260.451 1.00 89.98  ? 152 HIS B NE2 1 
ATOM   7328  N  N   . LEU B 1 153 ? 219.878 218.343 259.451 1.00 70.15  ? 153 LEU B N   1 
ATOM   7329  C  CA  . LEU B 1 153 ? 219.266 217.562 258.384 1.00 66.86  ? 153 LEU B CA  1 
ATOM   7330  C  C   . LEU B 1 153 ? 218.428 218.519 257.539 1.00 66.91  ? 153 LEU B C   1 
ATOM   7331  O  O   . LEU B 1 153 ? 217.324 218.893 257.941 1.00 66.54  ? 153 LEU B O   1 
ATOM   7332  C  CB  . LEU B 1 153 ? 218.426 216.430 258.945 1.00 66.70  ? 153 LEU B CB  1 
ATOM   7333  C  CG  . LEU B 1 153 ? 218.528 215.122 258.169 1.00 65.99  ? 153 LEU B CG  1 
ATOM   7334  C  CD1 . LEU B 1 153 ? 219.978 214.720 258.006 1.00 64.77  ? 153 LEU B CD1 1 
ATOM   7335  C  CD2 . LEU B 1 153 ? 217.744 214.030 258.861 1.00 61.34  ? 153 LEU B CD2 1 
ATOM   7336  N  N   . ASP B 1 154 ? 218.968 218.914 256.389 1.00 64.91  ? 154 ASP B N   1 
ATOM   7337  C  CA  . ASP B 1 154 ? 218.243 219.761 255.446 1.00 60.66  ? 154 ASP B CA  1 
ATOM   7338  C  C   . ASP B 1 154 ? 217.440 218.871 254.501 1.00 57.68  ? 154 ASP B C   1 
ATOM   7339  O  O   . ASP B 1 154 ? 217.654 218.826 253.289 1.00 59.13  ? 154 ASP B O   1 
ATOM   7340  C  CB  . ASP B 1 154 ? 219.206 220.663 254.688 1.00 63.88  ? 154 ASP B CB  1 
ATOM   7341  C  CG  . ASP B 1 154 ? 220.048 221.522 255.608 1.00 74.42  ? 154 ASP B CG  1 
ATOM   7342  O  OD1 . ASP B 1 154 ? 219.859 221.441 256.840 1.00 73.41  ? 154 ASP B OD1 1 
ATOM   7343  O  OD2 . ASP B 1 154 ? 220.900 222.281 255.099 1.00 82.01  ? 154 ASP B OD2 1 
ATOM   7344  N  N   . ARG B 1 155 ? 216.495 218.145 255.090 1.00 56.01  ? 155 ARG B N   1 
ATOM   7345  C  CA  . ARG B 1 155 ? 215.740 217.116 254.382 1.00 53.81  ? 155 ARG B CA  1 
ATOM   7346  C  C   . ARG B 1 155 ? 214.269 217.496 254.378 1.00 47.02  ? 155 ARG B C   1 
ATOM   7347  O  O   . ARG B 1 155 ? 213.534 217.190 255.324 1.00 51.37  ? 155 ARG B O   1 
ATOM   7348  C  CB  . ARG B 1 155 ? 215.956 215.745 255.016 1.00 57.70  ? 155 ARG B CB  1 
ATOM   7349  C  CG  . ARG B 1 155 ? 217.330 215.154 254.743 1.00 58.87  ? 155 ARG B CG  1 
ATOM   7350  C  CD  . ARG B 1 155 ? 217.255 214.121 253.640 1.00 58.54  ? 155 ARG B CD  1 
ATOM   7351  N  NE  . ARG B 1 155 ? 216.868 214.729 252.375 1.00 56.53  ? 155 ARG B NE  1 
ATOM   7352  C  CZ  . ARG B 1 155 ? 216.048 214.170 251.500 1.00 58.44  ? 155 ARG B CZ  1 
ATOM   7353  N  NH1 . ARG B 1 155 ? 215.505 212.986 251.724 1.00 56.09  ? 155 ARG B NH1 1 
ATOM   7354  N  NH2 . ARG B 1 155 ? 215.759 214.818 250.377 1.00 60.00  ? 155 ARG B NH2 1 
ATOM   7355  N  N   . PRO B 1 156 ? 213.804 218.151 253.326 1.00 41.48  ? 156 PRO B N   1 
ATOM   7356  C  CA  . PRO B 1 156 ? 212.389 218.514 253.252 1.00 40.92  ? 156 PRO B CA  1 
ATOM   7357  C  C   . PRO B 1 156 ? 211.486 217.304 253.319 1.00 40.35  ? 156 PRO B C   1 
ATOM   7358  O  O   . PRO B 1 156 ? 211.465 216.475 252.407 1.00 49.45  ? 156 PRO B O   1 
ATOM   7359  C  CB  . PRO B 1 156 ? 212.276 219.212 251.895 1.00 50.40  ? 156 PRO B CB  1 
ATOM   7360  C  CG  . PRO B 1 156 ? 213.648 219.673 251.589 1.00 56.98  ? 156 PRO B CG  1 
ATOM   7361  C  CD  . PRO B 1 156 ? 214.568 218.654 252.178 1.00 51.07  ? 156 PRO B CD  1 
ATOM   7362  N  N   . VAL B 1 157 ? 210.736 217.199 254.404 1.00 37.50  ? 157 VAL B N   1 
ATOM   7363  C  CA  . VAL B 1 157 ? 209.755 216.146 254.592 1.00 37.62  ? 157 VAL B CA  1 
ATOM   7364  C  C   . VAL B 1 157 ? 208.456 216.795 255.027 1.00 37.93  ? 157 VAL B C   1 
ATOM   7365  O  O   . VAL B 1 157 ? 208.450 217.657 255.911 1.00 45.38  ? 157 VAL B O   1 
ATOM   7366  C  CB  . VAL B 1 157 ? 210.224 215.097 255.618 1.00 39.11  ? 157 VAL B CB  1 
ATOM   7367  C  CG1 . VAL B 1 157 ? 210.605 215.749 256.914 1.00 39.20  ? 157 VAL B CG1 1 
ATOM   7368  C  CG2 . VAL B 1 157 ? 209.139 214.080 255.856 1.00 42.75  ? 157 VAL B CG2 1 
ATOM   7369  N  N   . ILE B 1 158 ? 207.364 216.402 254.391 1.00 38.85  ? 158 ILE B N   1 
ATOM   7370  C  CA  . ILE B 1 158 ? 206.036 216.852 254.766 1.00 39.94  ? 158 ILE B CA  1 
ATOM   7371  C  C   . ILE B 1 158 ? 205.176 215.626 255.004 1.00 43.30  ? 158 ILE B C   1 
ATOM   7372  O  O   . ILE B 1 158 ? 205.516 214.521 254.591 1.00 54.02  ? 158 ILE B O   1 
ATOM   7373  C  CB  . ILE B 1 158 ? 205.430 217.773 253.696 1.00 49.77  ? 158 ILE B CB  1 
ATOM   7374  C  CG1 . ILE B 1 158 ? 205.156 216.979 252.423 1.00 55.90  ? 158 ILE B CG1 1 
ATOM   7375  C  CG2 . ILE B 1 158 ? 206.351 218.947 253.413 1.00 54.61  ? 158 ILE B CG2 1 
ATOM   7376  C  CD1 . ILE B 1 158 ? 203.732 216.741 252.129 1.00 60.51  ? 158 ILE B CD1 1 
ATOM   7377  N  N   . VAL B 1 159 ? 204.080 215.807 255.720 1.00 44.16  ? 159 VAL B N   1 
ATOM   7378  C  CA  . VAL B 1 159 ? 203.156 214.712 255.979 1.00 51.77  ? 159 VAL B CA  1 
ATOM   7379  C  C   . VAL B 1 159 ? 201.739 215.155 255.635 1.00 64.77  ? 159 VAL B C   1 
ATOM   7380  O  O   . VAL B 1 159 ? 201.396 216.339 255.740 1.00 70.37  ? 159 VAL B O   1 
ATOM   7381  C  CB  . VAL B 1 159 ? 203.242 214.212 257.432 1.00 44.90  ? 159 VAL B CB  1 
ATOM   7382  C  CG1 . VAL B 1 159 ? 204.670 213.926 257.797 1.00 44.03  ? 159 VAL B CG1 1 
ATOM   7383  C  CG2 . VAL B 1 159 ? 202.631 215.206 258.387 1.00 55.99  ? 159 VAL B CG2 1 
ATOM   7384  N  N   . LEU B 1 160 ? 200.918 214.189 255.226 1.00 69.13  ? 160 LEU B N   1 
ATOM   7385  C  CA  . LEU B 1 160 ? 199.611 214.429 254.638 1.00 70.85  ? 160 LEU B CA  1 
ATOM   7386  C  C   . LEU B 1 160 ? 198.540 213.590 255.317 1.00 79.35  ? 160 LEU B C   1 
ATOM   7387  O  O   . LEU B 1 160 ? 198.779 212.440 255.693 1.00 76.89  ? 160 LEU B O   1 
ATOM   7388  C  CB  . LEU B 1 160 ? 199.632 214.125 253.145 1.00 68.22  ? 160 LEU B CB  1 
ATOM   7389  C  CG  . LEU B 1 160 ? 200.700 214.882 252.377 1.00 66.80  ? 160 LEU B CG  1 
ATOM   7390  C  CD1 . LEU B 1 160 ? 200.736 214.454 250.935 1.00 75.81  ? 160 LEU B CD1 1 
ATOM   7391  C  CD2 . LEU B 1 160 ? 200.351 216.342 252.475 1.00 70.38  ? 160 LEU B CD2 1 
ATOM   7392  N  N   . ASP B 1 161 ? 197.353 214.179 255.456 1.00 87.95  ? 161 ASP B N   1 
ATOM   7393  C  CA  . ASP B 1 161 ? 196.177 213.482 255.948 1.00 92.77  ? 161 ASP B CA  1 
ATOM   7394  C  C   . ASP B 1 161 ? 195.615 212.592 254.843 1.00 94.00  ? 161 ASP B C   1 
ATOM   7395  O  O   . ASP B 1 161 ? 196.103 212.615 253.711 1.00 93.34  ? 161 ASP B O   1 
ATOM   7396  C  CB  . ASP B 1 161 ? 195.133 214.494 256.421 1.00 91.57  ? 161 ASP B CB  1 
ATOM   7397  C  CG  . ASP B 1 161 ? 195.158 214.699 257.921 1.00 89.25  ? 161 ASP B CG  1 
ATOM   7398  O  OD1 . ASP B 1 161 ? 195.542 213.756 258.645 1.00 87.20  ? 161 ASP B OD1 1 
ATOM   7399  O  OD2 . ASP B 1 161 ? 194.793 215.803 258.379 1.00 89.51  ? 161 ASP B OD2 1 
ATOM   7400  N  N   . PRO B 1 162 ? 194.595 211.778 255.142 1.00 96.20  ? 162 PRO B N   1 
ATOM   7401  C  CA  . PRO B 1 162 ? 193.921 211.056 254.050 1.00 95.64  ? 162 PRO B CA  1 
ATOM   7402  C  C   . PRO B 1 162 ? 193.389 211.982 252.972 1.00 94.57  ? 162 PRO B C   1 
ATOM   7403  O  O   . PRO B 1 162 ? 193.422 211.636 251.785 1.00 91.59  ? 162 PRO B O   1 
ATOM   7404  C  CB  . PRO B 1 162 ? 192.793 210.311 254.773 1.00 92.77  ? 162 PRO B CB  1 
ATOM   7405  C  CG  . PRO B 1 162 ? 193.323 210.087 256.137 1.00 91.72  ? 162 PRO B CG  1 
ATOM   7406  C  CD  . PRO B 1 162 ? 194.171 211.284 256.466 1.00 92.16  ? 162 PRO B CD  1 
ATOM   7407  N  N   . GLU B 1 163 ? 192.932 213.166 253.349 1.00 94.20  ? 163 GLU B N   1 
ATOM   7408  C  CA  . GLU B 1 163 ? 192.502 214.158 252.376 1.00 93.42  ? 163 GLU B CA  1 
ATOM   7409  C  C   . GLU B 1 163 ? 193.654 214.842 251.702 1.00 93.37  ? 163 GLU B C   1 
ATOM   7410  O  O   . GLU B 1 163 ? 193.429 215.870 251.062 1.00 93.27  ? 163 GLU B O   1 
ATOM   7411  C  CB  . GLU B 1 163 ? 191.598 215.195 253.045 1.00 97.03  ? 163 GLU B CB  1 
ATOM   7412  C  CG  . GLU B 1 163 ? 192.005 215.565 254.459 1.00 98.42  ? 163 GLU B CG  1 
ATOM   7413  C  CD  . GLU B 1 163 ? 191.043 216.546 255.101 1.00 97.75  ? 163 GLU B CD  1 
ATOM   7414  O  OE1 . GLU B 1 163 ? 189.864 216.576 254.692 1.00 101.59 ? 163 GLU B OE1 1 
ATOM   7415  O  OE2 . GLU B 1 163 ? 191.465 217.287 256.014 1.00 89.14  ? 163 GLU B OE2 1 
ATOM   7416  N  N   . ARG B 1 164 ? 194.861 214.298 251.844 1.00 91.58  ? 164 ARG B N   1 
ATOM   7417  C  CA  . ARG B 1 164 ? 196.063 214.831 251.205 1.00 90.01  ? 164 ARG B CA  1 
ATOM   7418  C  C   . ARG B 1 164 ? 196.351 216.270 251.625 1.00 91.62  ? 164 ARG B C   1 
ATOM   7419  O  O   . ARG B 1 164 ? 196.924 217.047 250.859 1.00 91.21  ? 164 ARG B O   1 
ATOM   7420  C  CB  . ARG B 1 164 ? 195.975 214.725 249.680 1.00 89.79  ? 164 ARG B CB  1 
ATOM   7421  C  CG  . ARG B 1 164 ? 195.528 213.364 249.189 1.00 90.47  ? 164 ARG B CG  1 
ATOM   7422  C  CD  . ARG B 1 164 ? 196.378 212.268 249.798 1.00 88.21  ? 164 ARG B CD  1 
ATOM   7423  N  NE  . ARG B 1 164 ? 195.722 210.968 249.745 1.00 91.91  ? 164 ARG B NE  1 
ATOM   7424  C  CZ  . ARG B 1 164 ? 196.164 209.941 249.033 1.00 91.79  ? 164 ARG B CZ  1 
ATOM   7425  N  NH1 . ARG B 1 164 ? 197.258 210.032 248.296 1.00 90.78  ? 164 ARG B NH1 1 
ATOM   7426  N  NH2 . ARG B 1 164 ? 195.491 208.795 249.062 1.00 89.38  ? 164 ARG B NH2 1 
ATOM   7427  N  N   . HIS B 1 165 ? 195.972 216.633 252.846 1.00 94.26  ? 165 HIS B N   1 
ATOM   7428  C  CA  . HIS B 1 165 ? 196.249 217.958 253.381 1.00 93.81  ? 165 HIS B CA  1 
ATOM   7429  C  C   . HIS B 1 165 ? 197.552 217.953 254.171 1.00 85.47  ? 165 HIS B C   1 
ATOM   7430  O  O   . HIS B 1 165 ? 197.858 216.999 254.888 1.00 84.92  ? 165 HIS B O   1 
ATOM   7431  C  CB  . HIS B 1 165 ? 195.108 218.430 254.283 1.00 94.80  ? 165 HIS B CB  1 
ATOM   7432  C  CG  . HIS B 1 165 ? 193.998 219.111 253.548 1.00 96.52  ? 165 HIS B CG  1 
ATOM   7433  N  ND1 . HIS B 1 165 ? 194.202 220.221 252.758 1.00 93.88  ? 165 HIS B ND1 1 
ATOM   7434  C  CD2 . HIS B 1 165 ? 192.672 218.846 253.490 1.00 98.38  ? 165 HIS B CD2 1 
ATOM   7435  C  CE1 . HIS B 1 165 ? 193.049 220.609 252.243 1.00 96.72  ? 165 HIS B CE1 1 
ATOM   7436  N  NE2 . HIS B 1 165 ? 192.105 219.790 252.670 1.00 101.59 ? 165 HIS B NE2 1 
ATOM   7437  N  N   . ILE B 1 166 ? 198.319 219.037 254.034 1.00 80.60  ? 166 ILE B N   1 
ATOM   7438  C  CA  . ILE B 1 166 ? 199.542 219.181 254.812 1.00 74.50  ? 166 ILE B CA  1 
ATOM   7439  C  C   . ILE B 1 166 ? 199.186 219.251 256.287 1.00 77.06  ? 166 ILE B C   1 
ATOM   7440  O  O   . ILE B 1 166 ? 198.363 220.075 256.704 1.00 82.67  ? 166 ILE B O   1 
ATOM   7441  C  CB  . ILE B 1 166 ? 200.315 220.430 254.374 1.00 75.98  ? 166 ILE B CB  1 
ATOM   7442  C  CG1 . ILE B 1 166 ? 200.669 220.355 252.892 1.00 81.57  ? 166 ILE B CG1 1 
ATOM   7443  C  CG2 . ILE B 1 166 ? 201.567 220.597 255.213 1.00 71.21  ? 166 ILE B CG2 1 
ATOM   7444  C  CD1 . ILE B 1 166 ? 201.994 219.721 252.617 1.00 74.72  ? 166 ILE B CD1 1 
ATOM   7445  N  N   . VAL B 1 167 ? 199.801 218.384 257.087 1.00 70.54  ? 167 VAL B N   1 
ATOM   7446  C  CA  . VAL B 1 167 ? 199.565 218.343 258.519 1.00 62.56  ? 167 VAL B CA  1 
ATOM   7447  C  C   . VAL B 1 167 ? 200.784 218.800 259.306 1.00 58.53  ? 167 VAL B C   1 
ATOM   7448  O  O   . VAL B 1 167 ? 200.648 219.486 260.320 1.00 63.54  ? 167 VAL B O   1 
ATOM   7449  C  CB  . VAL B 1 167 ? 199.117 216.940 258.967 1.00 61.56  ? 167 VAL B CB  1 
ATOM   7450  C  CG1 . VAL B 1 167 ? 198.421 217.029 260.302 1.00 60.21  ? 167 VAL B CG1 1 
ATOM   7451  C  CG2 . VAL B 1 167 ? 198.198 216.339 257.944 1.00 70.39  ? 167 VAL B CG2 1 
ATOM   7452  N  N   . GLN B 1 168 ? 201.979 218.426 258.865 1.00 54.01  ? 168 GLN B N   1 
ATOM   7453  C  CA  . GLN B 1 168 ? 203.194 218.868 259.527 1.00 48.12  ? 168 GLN B CA  1 
ATOM   7454  C  C   . GLN B 1 168 ? 204.311 218.954 258.502 1.00 45.03  ? 168 GLN B C   1 
ATOM   7455  O  O   . GLN B 1 168 ? 204.507 218.025 257.716 1.00 51.69  ? 168 GLN B O   1 
ATOM   7456  C  CB  . GLN B 1 168 ? 203.578 217.924 260.664 1.00 45.42  ? 168 GLN B CB  1 
ATOM   7457  C  CG  . GLN B 1 168 ? 204.716 218.427 261.501 1.00 44.36  ? 168 GLN B CG  1 
ATOM   7458  C  CD  . GLN B 1 168 ? 206.033 217.822 261.095 1.00 45.39  ? 168 GLN B CD  1 
ATOM   7459  O  OE1 . GLN B 1 168 ? 206.133 216.619 260.887 1.00 43.85  ? 168 GLN B OE1 1 
ATOM   7460  N  NE2 . GLN B 1 168 ? 207.058 218.654 260.986 1.00 49.22  ? 168 GLN B NE2 1 
ATOM   7461  N  N   . CYS B 1 169 ? 205.029 220.066 258.516 1.00 39.08  ? 169 CYS B N   1 
ATOM   7462  C  CA  . CYS B 1 169 ? 206.146 220.307 257.623 1.00 43.02  ? 169 CYS B CA  1 
ATOM   7463  C  C   . CYS B 1 169 ? 207.307 220.880 258.419 1.00 47.60  ? 169 CYS B C   1 
ATOM   7464  O  O   . CYS B 1 169 ? 207.111 221.622 259.381 1.00 54.54  ? 169 CYS B O   1 
ATOM   7465  C  CB  . CYS B 1 169 ? 205.744 221.252 256.500 1.00 55.66  ? 169 CYS B CB  1 
ATOM   7466  S  SG  . CYS B 1 169 ? 206.099 222.987 256.823 1.00 85.94  ? 169 CYS B SG  1 
ATOM   7467  N  N   . ASN B 1 170 ? 208.517 220.523 258.019 1.00 46.22  ? 170 ASN B N   1 
ATOM   7468  C  CA  . ASN B 1 170 ? 209.698 220.820 258.808 1.00 50.77  ? 170 ASN B CA  1 
ATOM   7469  C  C   . ASN B 1 170 ? 210.361 222.115 258.347 1.00 60.28  ? 170 ASN B C   1 
ATOM   7470  O  O   . ASN B 1 170 ? 209.908 222.791 257.420 1.00 64.27  ? 170 ASN B O   1 
ATOM   7471  C  CB  . ASN B 1 170 ? 210.679 219.656 258.748 1.00 46.02  ? 170 ASN B CB  1 
ATOM   7472  C  CG  . ASN B 1 170 ? 211.127 219.362 257.359 1.00 49.82  ? 170 ASN B CG  1 
ATOM   7473  O  OD1 . ASN B 1 170 ? 210.459 219.723 256.397 1.00 55.73  ? 170 ASN B OD1 1 
ATOM   7474  N  ND2 . ASN B 1 170 ? 212.261 218.691 257.234 1.00 49.48  ? 170 ASN B ND2 1 
ATOM   7475  N  N   . ARG B 1 171 ? 211.462 222.459 259.022 1.00 62.89  ? 171 ARG B N   1 
ATOM   7476  C  CA  . ARG B 1 171 ? 212.158 223.715 258.761 1.00 62.81  ? 171 ARG B CA  1 
ATOM   7477  C  C   . ARG B 1 171 ? 212.788 223.735 257.376 1.00 65.36  ? 171 ARG B C   1 
ATOM   7478  O  O   . ARG B 1 171 ? 212.782 224.773 256.706 1.00 71.50  ? 171 ARG B O   1 
ATOM   7479  C  CB  . ARG B 1 171 ? 213.222 223.952 259.829 1.00 61.03  ? 171 ARG B CB  1 
ATOM   7480  C  CG  . ARG B 1 171 ? 214.081 225.173 259.585 1.00 69.44  ? 171 ARG B CG  1 
ATOM   7481  C  CD  . ARG B 1 171 ? 215.242 225.235 260.557 1.00 74.48  ? 171 ARG B CD  1 
ATOM   7482  N  NE  . ARG B 1 171 ? 216.163 226.320 260.237 1.00 82.94  ? 171 ARG B NE  1 
ATOM   7483  C  CZ  . ARG B 1 171 ? 217.183 226.686 261.001 1.00 81.42  ? 171 ARG B CZ  1 
ATOM   7484  N  NH1 . ARG B 1 171 ? 217.443 226.077 262.147 1.00 78.76  ? 171 ARG B NH1 1 
ATOM   7485  N  NH2 . ARG B 1 171 ? 217.961 227.690 260.607 1.00 82.51  ? 171 ARG B NH2 1 
ATOM   7486  N  N   . ALA B 1 172 ? 213.348 222.608 256.932 1.00 60.96  ? 172 ALA B N   1 
ATOM   7487  C  CA  . ALA B 1 172 ? 213.980 222.578 255.617 1.00 58.76  ? 172 ALA B CA  1 
ATOM   7488  C  C   . ALA B 1 172 ? 212.966 222.855 254.516 1.00 58.22  ? 172 ALA B C   1 
ATOM   7489  O  O   . ALA B 1 172 ? 213.259 223.578 253.558 1.00 66.00  ? 172 ALA B O   1 
ATOM   7490  C  CB  . ALA B 1 172 ? 214.669 221.236 255.391 1.00 58.16  ? 172 ALA B CB  1 
ATOM   7491  N  N   . PHE B 1 173 ? 211.763 222.306 254.649 1.00 52.32  ? 173 PHE B N   1 
ATOM   7492  C  CA  . PHE B 1 173 ? 210.724 222.521 253.651 1.00 55.73  ? 173 PHE B CA  1 
ATOM   7493  C  C   . PHE B 1 173 ? 210.288 223.981 253.599 1.00 69.40  ? 173 PHE B C   1 
ATOM   7494  O  O   . PHE B 1 173 ? 210.160 224.552 252.510 1.00 79.68  ? 173 PHE B O   1 
ATOM   7495  C  CB  . PHE B 1 173 ? 209.540 221.618 253.955 1.00 56.59  ? 173 PHE B CB  1 
ATOM   7496  C  CG  . PHE B 1 173 ? 208.334 221.899 253.130 1.00 59.00  ? 173 PHE B CG  1 
ATOM   7497  C  CD1 . PHE B 1 173 ? 208.248 221.451 251.831 1.00 64.89  ? 173 PHE B CD1 1 
ATOM   7498  C  CD2 . PHE B 1 173 ? 207.269 222.575 253.667 1.00 58.13  ? 173 PHE B CD2 1 
ATOM   7499  C  CE1 . PHE B 1 173 ? 207.128 221.696 251.084 1.00 64.28  ? 173 PHE B CE1 1 
ATOM   7500  C  CE2 . PHE B 1 173 ? 206.151 222.820 252.925 1.00 61.95  ? 173 PHE B CE2 1 
ATOM   7501  C  CZ  . PHE B 1 173 ? 206.080 222.383 251.633 1.00 62.28  ? 173 PHE B CZ  1 
ATOM   7502  N  N   . THR B 1 174 ? 210.048 224.602 254.759 1.00 74.40  ? 174 THR B N   1 
ATOM   7503  C  CA  . THR B 1 174 ? 209.668 226.013 254.771 1.00 76.17  ? 174 THR B CA  1 
ATOM   7504  C  C   . THR B 1 174 ? 210.786 226.882 254.218 1.00 74.53  ? 174 THR B C   1 
ATOM   7505  O  O   . THR B 1 174 ? 210.533 227.838 253.479 1.00 78.11  ? 174 THR B O   1 
ATOM   7506  C  CB  . THR B 1 174 ? 209.311 226.470 256.184 1.00 74.02  ? 174 THR B CB  1 
ATOM   7507  O  OG1 . THR B 1 174 ? 210.334 226.056 257.094 1.00 72.23  ? 174 THR B OG1 1 
ATOM   7508  C  CG2 . THR B 1 174 ? 208.011 225.869 256.615 1.00 80.84  ? 174 THR B CG2 1 
ATOM   7509  N  N   . GLU B 1 175 ? 212.030 226.574 254.579 1.00 72.40  ? 175 GLU B N   1 
ATOM   7510  C  CA  . GLU B 1 175 ? 213.148 227.372 254.102 1.00 73.27  ? 175 GLU B CA  1 
ATOM   7511  C  C   . GLU B 1 175 ? 213.289 227.273 252.593 1.00 73.63  ? 175 GLU B C   1 
ATOM   7512  O  O   . GLU B 1 175 ? 213.491 228.285 251.913 1.00 78.59  ? 175 GLU B O   1 
ATOM   7513  C  CB  . GLU B 1 175 ? 214.434 226.925 254.785 1.00 74.26  ? 175 GLU B CB  1 
ATOM   7514  C  CG  . GLU B 1 175 ? 215.584 227.878 254.599 1.00 76.96  ? 175 GLU B CG  1 
ATOM   7515  C  CD  . GLU B 1 175 ? 216.575 227.803 255.732 1.00 82.88  ? 175 GLU B CD  1 
ATOM   7516  O  OE1 . GLU B 1 175 ? 216.134 227.670 256.891 1.00 81.61  ? 175 GLU B OE1 1 
ATOM   7517  O  OE2 . GLU B 1 175 ? 217.793 227.877 255.468 1.00 90.81  ? 175 GLU B OE2 1 
ATOM   7518  N  N   . MET B 1 176 ? 213.182 226.062 252.047 1.00 71.89  ? 176 MET B N   1 
ATOM   7519  C  CA  . MET B 1 176 ? 213.395 225.885 250.617 1.00 73.67  ? 176 MET B CA  1 
ATOM   7520  C  C   . MET B 1 176 ? 212.227 226.419 249.808 1.00 77.20  ? 176 MET B C   1 
ATOM   7521  O  O   . MET B 1 176 ? 212.427 227.094 248.793 1.00 85.21  ? 176 MET B O   1 
ATOM   7522  C  CB  . MET B 1 176 ? 213.619 224.411 250.299 1.00 75.95  ? 176 MET B CB  1 
ATOM   7523  C  CG  . MET B 1 176 ? 214.001 224.150 248.863 1.00 79.92  ? 176 MET B CG  1 
ATOM   7524  S  SD  . MET B 1 176 ? 214.344 222.409 248.559 1.00 88.09  ? 176 MET B SD  1 
ATOM   7525  C  CE  . MET B 1 176 ? 215.936 222.236 249.355 1.00 76.52  ? 176 MET B CE  1 
ATOM   7526  N  N   . PHE B 1 177 ? 211.002 226.123 250.233 1.00 77.19  ? 177 PHE B N   1 
ATOM   7527  C  CA  . PHE B 1 177 ? 209.815 226.469 249.466 1.00 80.31  ? 177 PHE B CA  1 
ATOM   7528  C  C   . PHE B 1 177 ? 209.085 227.658 250.063 1.00 82.11  ? 177 PHE B C   1 
ATOM   7529  O  O   . PHE B 1 177 ? 207.903 227.858 249.781 1.00 82.78  ? 177 PHE B O   1 
ATOM   7530  C  CB  . PHE B 1 177 ? 208.879 225.267 249.348 1.00 82.81  ? 177 PHE B CB  1 
ATOM   7531  C  CG  . PHE B 1 177 ? 209.337 224.240 248.350 1.00 86.79  ? 177 PHE B CG  1 
ATOM   7532  C  CD1 . PHE B 1 177 ? 210.633 223.752 248.380 1.00 82.85  ? 177 PHE B CD1 1 
ATOM   7533  C  CD2 . PHE B 1 177 ? 208.474 223.759 247.388 1.00 93.64  ? 177 PHE B CD2 1 
ATOM   7534  C  CE1 . PHE B 1 177 ? 211.057 222.811 247.475 1.00 84.99  ? 177 PHE B CE1 1 
ATOM   7535  C  CE2 . PHE B 1 177 ? 208.897 222.813 246.474 1.00 91.85  ? 177 PHE B CE2 1 
ATOM   7536  C  CZ  . PHE B 1 177 ? 210.192 222.342 246.520 1.00 87.69  ? 177 PHE B CZ  1 
ATOM   7537  N  N   . GLY B 1 178 ? 209.741 228.404 250.947 1.00 82.90  ? 178 GLY B N   1 
ATOM   7538  C  CA  . GLY B 1 178 ? 209.276 229.718 251.333 1.00 90.76  ? 178 GLY B CA  1 
ATOM   7539  C  C   . GLY B 1 178 ? 207.957 229.750 252.059 1.00 93.98  ? 178 GLY B C   1 
ATOM   7540  O  O   . GLY B 1 178 ? 207.635 230.772 252.676 1.00 97.15  ? 178 GLY B O   1 
ATOM   7541  N  N   . TYR B 1 179 ? 207.188 228.672 252.019 1.00 89.18  ? 179 TYR B N   1 
ATOM   7542  C  CA  . TYR B 1 179 ? 205.868 228.636 252.624 1.00 95.17  ? 179 TYR B CA  1 
ATOM   7543  C  C   . TYR B 1 179 ? 205.988 228.122 254.052 1.00 98.69  ? 179 TYR B C   1 
ATOM   7544  O  O   . TYR B 1 179 ? 206.253 226.936 254.270 1.00 97.28  ? 179 TYR B O   1 
ATOM   7545  C  CB  . TYR B 1 179 ? 204.940 227.759 251.791 1.00 95.82  ? 179 TYR B CB  1 
ATOM   7546  C  CG  . TYR B 1 179 ? 204.541 228.405 250.489 1.00 102.43 ? 179 TYR B CG  1 
ATOM   7547  C  CD1 . TYR B 1 179 ? 203.737 229.537 250.473 1.00 110.14 ? 179 TYR B CD1 1 
ATOM   7548  C  CD2 . TYR B 1 179 ? 205.001 227.914 249.278 1.00 105.15 ? 179 TYR B CD2 1 
ATOM   7549  C  CE1 . TYR B 1 179 ? 203.375 230.140 249.283 1.00 115.59 ? 179 TYR B CE1 1 
ATOM   7550  C  CE2 . TYR B 1 179 ? 204.645 228.508 248.083 1.00 111.86 ? 179 TYR B CE2 1 
ATOM   7551  C  CZ  . TYR B 1 179 ? 203.834 229.622 248.090 1.00 115.20 ? 179 TYR B CZ  1 
ATOM   7552  O  OH  . TYR B 1 179 ? 203.482 230.218 246.901 1.00 114.28 ? 179 TYR B OH  1 
ATOM   7553  N  N   . CYS B 1 180 ? 205.789 229.014 255.018 1.00 101.61 ? 180 CYS B N   1 
ATOM   7554  C  CA  . CYS B 1 180 ? 205.872 228.645 256.418 1.00 99.47  ? 180 CYS B CA  1 
ATOM   7555  C  C   . CYS B 1 180 ? 204.696 227.751 256.790 1.00 102.64 ? 180 CYS B C   1 
ATOM   7556  O  O   . CYS B 1 180 ? 203.719 227.627 256.050 1.00 104.39 ? 180 CYS B O   1 
ATOM   7557  C  CB  . CYS B 1 180 ? 205.899 229.888 257.302 1.00 102.84 ? 180 CYS B CB  1 
ATOM   7558  S  SG  . CYS B 1 180 ? 204.475 230.981 257.095 1.00 115.62 ? 180 CYS B SG  1 
ATOM   7559  N  N   . ILE B 1 181 ? 204.804 227.121 257.962 1.00 101.68 ? 181 ILE B N   1 
ATOM   7560  C  CA  . ILE B 1 181 ? 203.764 226.199 258.411 1.00 103.62 ? 181 ILE B CA  1 
ATOM   7561  C  C   . ILE B 1 181 ? 202.423 226.912 258.504 1.00 110.15 ? 181 ILE B C   1 
ATOM   7562  O  O   . ILE B 1 181 ? 201.379 226.349 258.153 1.00 111.22 ? 181 ILE B O   1 
ATOM   7563  C  CB  . ILE B 1 181 ? 204.161 225.560 259.753 1.00 97.02  ? 181 ILE B CB  1 
ATOM   7564  C  CG1 . ILE B 1 181 ? 202.950 224.893 260.411 1.00 101.20 ? 181 ILE B CG1 1 
ATOM   7565  C  CG2 . ILE B 1 181 ? 204.777 226.597 260.673 1.00 93.19  ? 181 ILE B CG2 1 
ATOM   7566  C  CD1 . ILE B 1 181 ? 202.449 223.669 259.686 1.00 99.65  ? 181 ILE B CD1 1 
ATOM   7567  N  N   . SER B 1 182 ? 202.429 228.162 258.968 1.00 110.57 ? 182 SER B N   1 
ATOM   7568  C  CA  . SER B 1 182 ? 201.190 228.927 259.029 1.00 111.17 ? 182 SER B CA  1 
ATOM   7569  C  C   . SER B 1 182 ? 200.592 229.111 257.641 1.00 113.20 ? 182 SER B C   1 
ATOM   7570  O  O   . SER B 1 182 ? 199.366 229.117 257.479 1.00 112.11 ? 182 SER B O   1 
ATOM   7571  C  CB  . SER B 1 182 ? 201.444 230.280 259.691 1.00 112.26 ? 182 SER B CB  1 
ATOM   7572  O  OG  . SER B 1 182 ? 202.597 230.900 259.152 1.00 114.49 ? 182 SER B OG  1 
ATOM   7573  N  N   . GLU B 1 183 ? 201.439 229.257 256.627 1.00 112.67 ? 183 GLU B N   1 
ATOM   7574  C  CA  . GLU B 1 183 ? 200.989 229.451 255.257 1.00 111.14 ? 183 GLU B CA  1 
ATOM   7575  C  C   . GLU B 1 183 ? 201.052 228.180 254.422 1.00 110.00 ? 183 GLU B C   1 
ATOM   7576  O  O   . GLU B 1 183 ? 200.810 228.241 253.213 1.00 109.64 ? 183 GLU B O   1 
ATOM   7577  C  CB  . GLU B 1 183 ? 201.814 230.553 254.587 1.00 111.08 ? 183 GLU B CB  1 
ATOM   7578  C  CG  . GLU B 1 183 ? 201.527 231.945 255.128 1.00 114.79 ? 183 GLU B CG  1 
ATOM   7579  C  CD  . GLU B 1 183 ? 202.156 233.041 254.292 1.00 117.94 ? 183 GLU B CD  1 
ATOM   7580  O  OE1 . GLU B 1 183 ? 203.380 233.254 254.415 1.00 115.43 ? 183 GLU B OE1 1 
ATOM   7581  O  OE2 . GLU B 1 183 ? 201.426 233.690 253.513 1.00 122.10 ? 183 GLU B OE2 1 
ATOM   7582  N  N   . ALA B 1 184 ? 201.371 227.035 255.026 1.00 108.96 ? 184 ALA B N   1 
ATOM   7583  C  CA  . ALA B 1 184 ? 201.434 225.776 254.299 1.00 107.39 ? 184 ALA B CA  1 
ATOM   7584  C  C   . ALA B 1 184 ? 200.414 224.746 254.759 1.00 103.59 ? 184 ALA B C   1 
ATOM   7585  O  O   . ALA B 1 184 ? 200.312 223.685 254.135 1.00 100.75 ? 184 ALA B O   1 
ATOM   7586  C  CB  . ALA B 1 184 ? 202.839 225.167 254.400 1.00 100.87 ? 184 ALA B CB  1 
ATOM   7587  N  N   . SER B 1 185 ? 199.662 225.018 255.819 1.00 102.19 ? 185 SER B N   1 
ATOM   7588  C  CA  . SER B 1 185 ? 198.695 224.061 256.330 1.00 99.56  ? 185 SER B CA  1 
ATOM   7589  C  C   . SER B 1 185 ? 197.305 224.334 255.772 1.00 99.47  ? 185 SER B C   1 
ATOM   7590  O  O   . SER B 1 185 ? 197.020 225.408 255.239 1.00 100.96 ? 185 SER B O   1 
ATOM   7591  C  CB  . SER B 1 185 ? 198.648 224.098 257.856 1.00 99.77  ? 185 SER B CB  1 
ATOM   7592  O  OG  . SER B 1 185 ? 197.461 223.488 258.333 1.00 93.49  ? 185 SER B OG  1 
ATOM   7593  N  N   . GLY B 1 186 ? 196.436 223.337 255.905 1.00 96.87  ? 186 GLY B N   1 
ATOM   7594  C  CA  . GLY B 1 186 ? 195.053 223.477 255.502 1.00 101.23 ? 186 GLY B CA  1 
ATOM   7595  C  C   . GLY B 1 186 ? 194.797 223.384 254.017 1.00 105.11 ? 186 GLY B C   1 
ATOM   7596  O  O   . GLY B 1 186 ? 193.669 223.642 253.583 1.00 106.18 ? 186 GLY B O   1 
ATOM   7597  N  N   . MET B 1 187 ? 195.802 223.023 253.222 1.00 103.92 ? 187 MET B N   1 
ATOM   7598  C  CA  . MET B 1 187 ? 195.635 222.922 251.781 1.00 101.82 ? 187 MET B CA  1 
ATOM   7599  C  C   . MET B 1 187 ? 196.576 221.859 251.234 1.00 98.10  ? 187 MET B C   1 
ATOM   7600  O  O   . MET B 1 187 ? 197.596 221.528 251.842 1.00 96.93  ? 187 MET B O   1 
ATOM   7601  C  CB  . MET B 1 187 ? 195.872 224.270 251.093 1.00 101.62 ? 187 MET B CB  1 
ATOM   7602  C  CG  . MET B 1 187 ? 197.286 224.473 250.602 1.00 102.57 ? 187 MET B CG  1 
ATOM   7603  S  SD  . MET B 1 187 ? 198.330 225.062 251.943 1.00 108.41 ? 187 MET B SD  1 
ATOM   7604  C  CE  . MET B 1 187 ? 198.182 226.832 251.728 1.00 104.80 ? 187 MET B CE  1 
ATOM   7605  N  N   . GLN B 1 188 ? 196.209 221.328 250.072 1.00 97.44  ? 188 GLN B N   1 
ATOM   7606  C  CA  . GLN B 1 188 ? 196.970 220.272 249.435 1.00 94.44  ? 188 GLN B CA  1 
ATOM   7607  C  C   . GLN B 1 188 ? 198.330 220.793 248.990 1.00 95.32  ? 188 GLN B C   1 
ATOM   7608  O  O   . GLN B 1 188 ? 198.511 221.995 248.792 1.00 97.72  ? 188 GLN B O   1 
ATOM   7609  C  CB  . GLN B 1 188 ? 196.206 219.719 248.235 1.00 96.54  ? 188 GLN B CB  1 
ATOM   7610  C  CG  . GLN B 1 188 ? 195.326 218.533 248.556 1.00 95.00  ? 188 GLN B CG  1 
ATOM   7611  C  CD  . GLN B 1 188 ? 194.276 218.863 249.590 1.00 95.38  ? 188 GLN B CD  1 
ATOM   7612  O  OE1 . GLN B 1 188 ? 194.360 218.425 250.734 1.00 93.11  ? 188 GLN B OE1 1 
ATOM   7613  N  NE2 . GLN B 1 188 ? 193.277 219.640 249.192 1.00 98.06  ? 188 GLN B NE2 1 
ATOM   7614  N  N   . PRO B 1 189 ? 199.315 219.905 248.857 1.00 93.25  ? 189 PRO B N   1 
ATOM   7615  C  CA  . PRO B 1 189 ? 200.627 220.354 248.364 1.00 98.50  ? 189 PRO B CA  1 
ATOM   7616  C  C   . PRO B 1 189 ? 200.589 220.952 246.967 1.00 105.23 ? 189 PRO B C   1 
ATOM   7617  O  O   . PRO B 1 189 ? 201.270 221.954 246.720 1.00 108.75 ? 189 PRO B O   1 
ATOM   7618  C  CB  . PRO B 1 189 ? 201.471 219.073 248.412 1.00 95.38  ? 189 PRO B CB  1 
ATOM   7619  C  CG  . PRO B 1 189 ? 200.788 218.209 249.417 1.00 92.04  ? 189 PRO B CG  1 
ATOM   7620  C  CD  . PRO B 1 189 ? 199.329 218.490 249.254 1.00 90.19  ? 189 PRO B CD  1 
ATOM   7621  N  N   . ASP B 1 190 ? 199.810 220.378 246.043 1.00 105.32 ? 190 ASP B N   1 
ATOM   7622  C  CA  . ASP B 1 190 ? 199.819 220.886 244.673 1.00 105.78 ? 190 ASP B CA  1 
ATOM   7623  C  C   . ASP B 1 190 ? 199.213 222.281 244.601 1.00 104.53 ? 190 ASP B C   1 
ATOM   7624  O  O   . ASP B 1 190 ? 199.785 223.183 243.977 1.00 101.58 ? 190 ASP B O   1 
ATOM   7625  C  CB  . ASP B 1 190 ? 199.082 219.923 243.738 1.00 102.92 ? 190 ASP B CB  1 
ATOM   7626  C  CG  . ASP B 1 190 ? 197.598 219.829 244.033 1.00 101.45 ? 190 ASP B CG  1 
ATOM   7627  O  OD1 . ASP B 1 190 ? 197.181 220.198 245.150 1.00 101.14 ? 190 ASP B OD1 1 
ATOM   7628  O  OD2 . ASP B 1 190 ? 196.844 219.387 243.141 1.00 99.48  ? 190 ASP B OD2 1 
ATOM   7629  N  N   . THR B 1 191 ? 198.067 222.482 245.253 1.00 104.68 ? 191 THR B N   1 
ATOM   7630  C  CA  . THR B 1 191 ? 197.469 223.809 245.306 1.00 105.86 ? 191 THR B CA  1 
ATOM   7631  C  C   . THR B 1 191 ? 198.388 224.781 246.027 1.00 103.70 ? 191 THR B C   1 
ATOM   7632  O  O   . THR B 1 191 ? 198.462 225.964 245.672 1.00 103.65 ? 191 THR B O   1 
ATOM   7633  C  CB  . THR B 1 191 ? 196.109 223.742 245.998 1.00 105.38 ? 191 THR B CB  1 
ATOM   7634  O  OG1 . THR B 1 191 ? 195.345 222.662 245.448 1.00 103.98 ? 191 THR B OG1 1 
ATOM   7635  C  CG2 . THR B 1 191 ? 195.345 225.044 245.801 1.00 105.37 ? 191 THR B CG2 1 
ATOM   7636  N  N   . LEU B 1 192 ? 199.099 224.296 247.042 1.00 103.85 ? 192 LEU B N   1 
ATOM   7637  C  CA  . LEU B 1 192 ? 200.098 225.112 247.715 1.00 106.67 ? 192 LEU B CA  1 
ATOM   7638  C  C   . LEU B 1 192 ? 201.219 225.498 246.765 1.00 106.77 ? 192 LEU B C   1 
ATOM   7639  O  O   . LEU B 1 192 ? 201.791 226.586 246.889 1.00 106.40 ? 192 LEU B O   1 
ATOM   7640  C  CB  . LEU B 1 192 ? 200.657 224.344 248.913 1.00 107.76 ? 192 LEU B CB  1 
ATOM   7641  C  CG  . LEU B 1 192 ? 201.322 225.027 250.107 1.00 106.80 ? 192 LEU B CG  1 
ATOM   7642  C  CD1 . LEU B 1 192 ? 201.584 223.982 251.177 1.00 103.28 ? 192 LEU B CD1 1 
ATOM   7643  C  CD2 . LEU B 1 192 ? 202.601 225.712 249.744 1.00 102.14 ? 192 LEU B CD2 1 
ATOM   7644  N  N   . LEU B 1 193 ? 201.532 224.635 245.807 1.00 105.42 ? 193 LEU B N   1 
ATOM   7645  C  CA  . LEU B 1 193 ? 202.736 224.796 245.010 1.00 109.21 ? 193 LEU B CA  1 
ATOM   7646  C  C   . LEU B 1 193 ? 202.482 225.690 243.807 1.00 111.21 ? 193 LEU B C   1 
ATOM   7647  O  O   . LEU B 1 193 ? 201.513 225.493 243.066 1.00 108.03 ? 193 LEU B O   1 
ATOM   7648  C  CB  . LEU B 1 193 ? 203.251 223.432 244.554 1.00 110.25 ? 193 LEU B CB  1 
ATOM   7649  C  CG  . LEU B 1 193 ? 204.120 222.701 245.577 1.00 112.21 ? 193 LEU B CG  1 
ATOM   7650  C  CD1 . LEU B 1 193 ? 204.305 221.241 245.194 1.00 105.95 ? 193 LEU B CD1 1 
ATOM   7651  C  CD2 . LEU B 1 193 ? 205.456 223.402 245.715 1.00 104.84 ? 193 LEU B CD2 1 
ATOM   7652  N  N   . ASN B 1 194 ? 203.359 226.673 243.618 1.00 114.40 ? 194 ASN B N   1 
ATOM   7653  C  CA  . ASN B 1 194 ? 203.370 227.471 242.401 1.00 113.65 ? 194 ASN B CA  1 
ATOM   7654  C  C   . ASN B 1 194 ? 204.106 226.687 241.328 1.00 111.53 ? 194 ASN B C   1 
ATOM   7655  O  O   . ASN B 1 194 ? 205.282 226.349 241.495 1.00 109.09 ? 194 ASN B O   1 
ATOM   7656  C  CB  . ASN B 1 194 ? 204.038 228.821 242.648 1.00 115.06 ? 194 ASN B CB  1 
ATOM   7657  C  CG  . ASN B 1 194 ? 203.765 229.817 241.538 1.00 115.98 ? 194 ASN B CG  1 
ATOM   7658  O  OD1 . ASN B 1 194 ? 202.855 229.632 240.730 1.00 114.48 ? 194 ASN B OD1 1 
ATOM   7659  N  ND2 . ASN B 1 194 ? 204.558 230.882 241.491 1.00 113.69 ? 194 ASN B ND2 1 
ATOM   7660  N  N   . THR B 1 195 ? 203.417 226.393 240.232 1.00 111.57 ? 195 THR B N   1 
ATOM   7661  C  CA  . THR B 1 195 ? 203.871 225.429 239.240 1.00 113.67 ? 195 THR B CA  1 
ATOM   7662  C  C   . THR B 1 195 ? 203.990 226.136 237.898 1.00 120.50 ? 195 THR B C   1 
ATOM   7663  O  O   . THR B 1 195 ? 203.016 226.734 237.438 1.00 123.03 ? 195 THR B O   1 
ATOM   7664  C  CB  . THR B 1 195 ? 202.908 224.231 239.144 1.00 30.00  ? 195 THR B CB  1 
ATOM   7665  O  OG1 . THR B 1 195 ? 201.594 224.697 238.817 1.00 30.00  ? 195 THR B OG1 1 
ATOM   7666  C  CG2 . THR B 1 195 ? 202.722 223.585 240.508 1.00 30.00  ? 195 THR B CG2 1 
ATOM   7667  N  N   . PRO B 1 196 ? 205.145 226.095 237.244 1.00 124.90 ? 196 PRO B N   1 
ATOM   7668  C  CA  . PRO B 1 196 ? 205.255 226.647 235.893 1.00 128.96 ? 196 PRO B CA  1 
ATOM   7669  C  C   . PRO B 1 196 ? 204.494 225.796 234.887 1.00 131.43 ? 196 PRO B C   1 
ATOM   7670  O  O   . PRO B 1 196 ? 204.194 224.623 235.115 1.00 128.27 ? 196 PRO B O   1 
ATOM   7671  C  CB  . PRO B 1 196 ? 206.761 226.621 235.612 1.00 124.45 ? 196 PRO B CB  1 
ATOM   7672  C  CG  . PRO B 1 196 ? 207.301 225.577 236.515 1.00 118.84 ? 196 PRO B CG  1 
ATOM   7673  C  CD  . PRO B 1 196 ? 206.408 225.503 237.716 1.00 118.32 ? 196 PRO B CD  1 
ATOM   7674  N  N   . GLU B 1 197 ? 204.183 226.419 233.754 1.00 132.58 ? 197 GLU B N   1 
ATOM   7675  C  CA  . GLU B 1 197 ? 203.320 225.814 232.742 1.00 134.80 ? 197 GLU B CA  1 
ATOM   7676  C  C   . GLU B 1 197 ? 204.175 224.982 231.793 1.00 137.68 ? 197 GLU B C   1 
ATOM   7677  O  O   . GLU B 1 197 ? 204.822 225.515 230.888 1.00 140.70 ? 197 GLU B O   1 
ATOM   7678  C  CB  . GLU B 1 197 ? 202.544 226.895 231.998 1.00 131.95 ? 197 GLU B CB  1 
ATOM   7679  C  CG  . GLU B 1 197 ? 201.111 226.520 231.671 1.00 129.09 ? 197 GLU B CG  1 
ATOM   7680  C  CD  . GLU B 1 197 ? 200.374 225.943 232.863 1.00 127.93 ? 197 GLU B CD  1 
ATOM   7681  O  OE1 . GLU B 1 197 ? 200.058 224.736 232.843 1.00 129.51 ? 197 GLU B OE1 1 
ATOM   7682  O  OE2 . GLU B 1 197 ? 200.111 226.698 233.822 1.00 123.64 ? 197 GLU B OE2 1 
ATOM   7683  N  N   . PHE B 1 198 ? 204.186 223.665 232.006 1.00 136.58 ? 198 PHE B N   1 
ATOM   7684  C  CA  . PHE B 1 198 ? 204.840 222.765 231.058 1.00 136.51 ? 198 PHE B CA  1 
ATOM   7685  C  C   . PHE B 1 198 ? 204.218 222.801 229.667 1.00 138.89 ? 198 PHE B C   1 
ATOM   7686  O  O   . PHE B 1 198 ? 204.976 222.845 228.683 1.00 136.91 ? 198 PHE B O   1 
ATOM   7687  C  CB  . PHE B 1 198 ? 204.850 221.336 231.612 1.00 131.50 ? 198 PHE B CB  1 
ATOM   7688  C  CG  . PHE B 1 198 ? 205.465 220.326 230.676 1.00 134.20 ? 198 PHE B CG  1 
ATOM   7689  C  CD1 . PHE B 1 198 ? 206.834 220.117 230.663 1.00 133.99 ? 198 PHE B CD1 1 
ATOM   7690  C  CD2 . PHE B 1 198 ? 204.676 219.585 229.813 1.00 135.19 ? 198 PHE B CD2 1 
ATOM   7691  C  CE1 . PHE B 1 198 ? 207.401 219.189 229.809 1.00 135.96 ? 198 PHE B CE1 1 
ATOM   7692  C  CE2 . PHE B 1 198 ? 205.236 218.656 228.958 1.00 132.74 ? 198 PHE B CE2 1 
ATOM   7693  C  CZ  . PHE B 1 198 ? 206.600 218.458 228.956 1.00 134.04 ? 198 PHE B CZ  1 
ATOM   7694  N  N   . PRO B 1 199 ? 202.877 222.783 229.492 1.00 139.07 ? 199 PRO B N   1 
ATOM   7695  C  CA  . PRO B 1 199 ? 201.781 222.815 230.472 1.00 135.47 ? 199 PRO B CA  1 
ATOM   7696  C  C   . PRO B 1 199 ? 201.218 221.457 230.880 1.00 131.34 ? 199 PRO B C   1 
ATOM   7697  O  O   . PRO B 1 199 ? 200.357 221.393 231.751 1.00 125.74 ? 199 PRO B O   1 
ATOM   7698  C  CB  . PRO B 1 199 ? 200.718 223.636 229.735 1.00 132.53 ? 199 PRO B CB  1 
ATOM   7699  C  CG  . PRO B 1 199 ? 200.912 223.270 228.274 1.00 131.38 ? 199 PRO B CG  1 
ATOM   7700  C  CD  . PRO B 1 199 ? 202.342 222.774 228.118 1.00 135.14 ? 199 PRO B CD  1 
ATOM   7701  N  N   . ALA B 1 200 ? 201.670 220.353 230.293 1.00 133.08 ? 200 ALA B N   1 
ATOM   7702  C  CA  . ALA B 1 200 ? 200.984 219.067 230.472 1.00 131.71 ? 200 ALA B CA  1 
ATOM   7703  C  C   . ALA B 1 200 ? 201.543 218.289 231.660 1.00 127.58 ? 200 ALA B C   1 
ATOM   7704  O  O   . ALA B 1 200 ? 200.824 218.012 232.623 1.00 123.39 ? 200 ALA B O   1 
ATOM   7705  C  CB  . ALA B 1 200 ? 201.073 218.245 229.185 1.00 130.94 ? 200 ALA B CB  1 
ATOM   7706  N  N   . ASP B 1 201 ? 202.826 217.935 231.604 1.00 129.21 ? 201 ASP B N   1 
ATOM   7707  C  CA  . ASP B 1 201 ? 203.412 217.035 232.590 1.00 122.07 ? 201 ASP B CA  1 
ATOM   7708  C  C   . ASP B 1 201 ? 203.404 217.631 233.992 1.00 117.38 ? 201 ASP B C   1 
ATOM   7709  O  O   . ASP B 1 201 ? 202.601 217.219 234.839 1.00 111.41 ? 201 ASP B O   1 
ATOM   7710  C  CB  . ASP B 1 201 ? 204.845 216.677 232.192 1.00 120.07 ? 201 ASP B CB  1 
ATOM   7711  C  CG  . ASP B 1 201 ? 204.902 215.668 231.064 1.00 121.40 ? 201 ASP B CG  1 
ATOM   7712  O  OD1 . ASP B 1 201 ? 204.073 215.766 230.135 1.00 128.47 ? 201 ASP B OD1 1 
ATOM   7713  O  OD2 . ASP B 1 201 ? 205.766 214.768 231.114 1.00 113.31 ? 201 ASP B OD2 1 
ATOM   7714  N  N   . ASN B 1 202 ? 204.230 218.660 234.214 1.00 119.32 ? 202 ASN B N   1 
ATOM   7715  C  CA  . ASN B 1 202 ? 204.474 219.174 235.560 1.00 117.90 ? 202 ASN B CA  1 
ATOM   7716  C  C   . ASN B 1 202 ? 203.199 219.586 236.278 1.00 114.17 ? 202 ASN B C   1 
ATOM   7717  O  O   . ASN B 1 202 ? 203.243 219.882 237.477 1.00 111.54 ? 202 ASN B O   1 
ATOM   7718  C  CB  . ASN B 1 202 ? 205.434 220.362 235.501 1.00 118.70 ? 202 ASN B CB  1 
ATOM   7719  C  CG  . ASN B 1 202 ? 206.824 219.965 235.051 1.00 113.90 ? 202 ASN B CG  1 
ATOM   7720  O  OD1 . ASN B 1 202 ? 207.702 219.685 235.867 1.00 106.51 ? 202 ASN B OD1 1 
ATOM   7721  N  ND2 . ASN B 1 202 ? 207.031 219.935 233.744 1.00 117.18 ? 202 ASN B ND2 1 
ATOM   7722  N  N   . ARG B 1 203 ? 202.070 219.619 235.578 1.00 113.13 ? 203 ARG B N   1 
ATOM   7723  C  CA  . ARG B 1 203 ? 200.770 219.793 236.210 1.00 107.37 ? 203 ARG B CA  1 
ATOM   7724  C  C   . ARG B 1 203 ? 200.122 218.455 236.548 1.00 99.90  ? 203 ARG B C   1 
ATOM   7725  O  O   . ARG B 1 203 ? 199.824 218.179 237.714 1.00 98.40  ? 203 ARG B O   1 
ATOM   7726  C  CB  . ARG B 1 203 ? 199.855 220.621 235.297 1.00 110.27 ? 203 ARG B CB  1 
ATOM   7727  C  CG  . ARG B 1 203 ? 200.256 222.088 235.069 1.00 113.14 ? 203 ARG B CG  1 
ATOM   7728  C  CD  . ARG B 1 203 ? 200.790 222.832 236.304 1.00 109.93 ? 203 ARG B CD  1 
ATOM   7729  N  NE  . ARG B 1 203 ? 200.228 222.357 237.564 1.00 105.83 ? 203 ARG B NE  1 
ATOM   7730  C  CZ  . ARG B 1 203 ? 198.969 222.536 237.939 1.00 105.93 ? 203 ARG B CZ  1 
ATOM   7731  N  NH1 . ARG B 1 203 ? 198.119 223.232 237.201 1.00 105.77 ? 203 ARG B NH1 1 
ATOM   7732  N  NH2 . ARG B 1 203 ? 198.550 222.005 239.083 1.00 104.40 ? 203 ARG B NH2 1 
ATOM   7733  N  N   . ILE B 1 204 ? 199.903 217.615 235.539 1.00 101.99 ? 204 ILE B N   1 
ATOM   7734  C  CA  . ILE B 1 204 ? 199.070 216.434 235.733 1.00 102.26 ? 204 ILE B CA  1 
ATOM   7735  C  C   . ILE B 1 204 ? 199.779 215.393 236.593 1.00 100.57 ? 204 ILE B C   1 
ATOM   7736  O  O   . ILE B 1 204 ? 199.150 214.751 237.447 1.00 98.96  ? 204 ILE B O   1 
ATOM   7737  C  CB  . ILE B 1 204 ? 198.633 215.858 234.374 1.00 107.02 ? 204 ILE B CB  1 
ATOM   7738  C  CG1 . ILE B 1 204 ? 198.089 216.966 233.472 1.00 109.17 ? 204 ILE B CG1 1 
ATOM   7739  C  CG2 . ILE B 1 204 ? 197.540 214.827 234.558 1.00 102.89 ? 204 ILE B CG2 1 
ATOM   7740  C  CD1 . ILE B 1 204 ? 197.877 216.533 232.036 1.00 107.08 ? 204 ILE B CD1 1 
ATOM   7741  N  N   . ARG B 1 205 ? 201.086 215.185 236.378 1.00 101.12 ? 205 ARG B N   1 
ATOM   7742  C  CA  . ARG B 1 205 ? 201.746 214.123 237.137 1.00 100.88 ? 205 ARG B CA  1 
ATOM   7743  C  C   . ARG B 1 205 ? 201.806 214.460 238.618 1.00 99.66  ? 205 ARG B C   1 
ATOM   7744  O  O   . ARG B 1 205 ? 201.841 213.554 239.457 1.00 93.99  ? 205 ARG B O   1 
ATOM   7745  C  CB  . ARG B 1 205 ? 203.157 213.827 236.625 1.00 98.86  ? 205 ARG B CB  1 
ATOM   7746  C  CG  . ARG B 1 205 ? 203.865 214.952 235.958 1.00 99.09  ? 205 ARG B CG  1 
ATOM   7747  C  CD  . ARG B 1 205 ? 205.145 214.496 235.309 1.00 99.31  ? 205 ARG B CD  1 
ATOM   7748  N  NE  . ARG B 1 205 ? 204.932 213.334 234.463 1.00 102.82 ? 205 ARG B NE  1 
ATOM   7749  C  CZ  . ARG B 1 205 ? 205.908 212.610 233.935 1.00 99.79  ? 205 ARG B CZ  1 
ATOM   7750  N  NH1 . ARG B 1 205 ? 207.179 212.914 234.134 1.00 98.10  ? 205 ARG B NH1 1 
ATOM   7751  N  NH2 . ARG B 1 205 ? 205.600 211.552 233.191 1.00 96.78  ? 205 ARG B NH2 1 
ATOM   7752  N  N   . LEU B 1 206 ? 201.815 215.749 238.961 1.00 103.56 ? 206 LEU B N   1 
ATOM   7753  C  CA  . LEU B 1 206 ? 201.771 216.136 240.366 1.00 100.79 ? 206 LEU B CA  1 
ATOM   7754  C  C   . LEU B 1 206 ? 200.497 215.627 241.021 1.00 97.30  ? 206 LEU B C   1 
ATOM   7755  O  O   . LEU B 1 206 ? 200.533 215.047 242.110 1.00 97.14  ? 206 LEU B O   1 
ATOM   7756  C  CB  . LEU B 1 206 ? 201.883 217.656 240.497 1.00 98.09  ? 206 LEU B CB  1 
ATOM   7757  C  CG  . LEU B 1 206 ? 201.979 218.266 241.897 1.00 95.38  ? 206 LEU B CG  1 
ATOM   7758  C  CD1 . LEU B 1 206 ? 203.028 217.566 242.718 1.00 93.51  ? 206 LEU B CD1 1 
ATOM   7759  C  CD2 . LEU B 1 206 ? 202.297 219.738 241.803 1.00 99.24  ? 206 LEU B CD2 1 
ATOM   7760  N  N   . GLN B 1 207 ? 199.358 215.815 240.353 1.00 98.00  ? 207 GLN B N   1 
ATOM   7761  C  CA  . GLN B 1 207 ? 198.097 215.318 240.892 1.00 97.20  ? 207 GLN B CA  1 
ATOM   7762  C  C   . GLN B 1 207 ? 198.081 213.797 240.933 1.00 93.42  ? 207 GLN B C   1 
ATOM   7763  O  O   . GLN B 1 207 ? 197.607 213.197 241.909 1.00 89.37  ? 207 GLN B O   1 
ATOM   7764  C  CB  . GLN B 1 207 ? 196.931 215.850 240.061 1.00 99.70  ? 207 GLN B CB  1 
ATOM   7765  C  CG  . GLN B 1 207 ? 196.827 217.369 240.048 1.00 103.54 ? 207 GLN B CG  1 
ATOM   7766  C  CD  . GLN B 1 207 ? 195.410 217.858 239.817 1.00 108.93 ? 207 GLN B CD  1 
ATOM   7767  O  OE1 . GLN B 1 207 ? 194.830 217.635 238.755 1.00 110.40 ? 207 GLN B OE1 1 
ATOM   7768  N  NE2 . GLN B 1 207 ? 194.847 218.533 240.813 1.00 110.25 ? 207 GLN B NE2 1 
ATOM   7769  N  N   . GLN B 1 208 ? 198.598 213.156 239.882 1.00 94.07  ? 208 GLN B N   1 
ATOM   7770  C  CA  . GLN B 1 208 ? 198.651 211.697 239.872 1.00 95.16  ? 208 GLN B CA  1 
ATOM   7771  C  C   . GLN B 1 208 ? 199.420 211.172 241.074 1.00 96.43  ? 208 GLN B C   1 
ATOM   7772  O  O   . GLN B 1 208 ? 198.925 210.319 241.819 1.00 91.76  ? 208 GLN B O   1 
ATOM   7773  C  CB  . GLN B 1 208 ? 199.285 211.184 238.580 1.00 96.15  ? 208 GLN B CB  1 
ATOM   7774  C  CG  . GLN B 1 208 ? 198.289 210.683 237.557 1.00 100.53 ? 208 GLN B CG  1 
ATOM   7775  C  CD  . GLN B 1 208 ? 197.860 211.759 236.593 1.00 105.24 ? 208 GLN B CD  1 
ATOM   7776  O  OE1 . GLN B 1 208 ? 198.681 212.301 235.857 1.00 104.98 ? 208 GLN B OE1 1 
ATOM   7777  N  NE2 . GLN B 1 208 ? 196.571 212.079 236.590 1.00 108.57 ? 208 GLN B NE2 1 
ATOM   7778  N  N   . LEU B 1 209 ? 200.633 211.686 241.288 1.00 99.10  ? 209 LEU B N   1 
ATOM   7779  C  CA  . LEU B 1 209 ? 201.436 211.247 242.424 1.00 91.93  ? 209 LEU B CA  1 
ATOM   7780  C  C   . LEU B 1 209 ? 200.750 211.562 243.741 1.00 86.29  ? 209 LEU B C   1 
ATOM   7781  O  O   . LEU B 1 209 ? 200.661 210.700 244.622 1.00 83.29  ? 209 LEU B O   1 
ATOM   7782  C  CB  . LEU B 1 209 ? 202.811 211.903 242.382 1.00 87.84  ? 209 LEU B CB  1 
ATOM   7783  C  CG  . LEU B 1 209 ? 203.658 211.631 243.620 1.00 81.14  ? 209 LEU B CG  1 
ATOM   7784  C  CD1 . LEU B 1 209 ? 204.298 210.260 243.537 1.00 75.05  ? 209 LEU B CD1 1 
ATOM   7785  C  CD2 . LEU B 1 209 ? 204.709 212.710 243.780 1.00 78.75  ? 209 LEU B CD2 1 
ATOM   7786  N  N   . LEU B 1 210 ? 200.237 212.782 243.889 1.00 89.01  ? 210 LEU B N   1 
ATOM   7787  C  CA  . LEU B 1 210 ? 199.634 213.178 245.152 1.00 88.95  ? 210 LEU B CA  1 
ATOM   7788  C  C   . LEU B 1 210 ? 198.391 212.375 245.476 1.00 87.06  ? 210 LEU B C   1 
ATOM   7789  O  O   . LEU B 1 210 ? 197.987 212.332 246.642 1.00 90.38  ? 210 LEU B O   1 
ATOM   7790  C  CB  . LEU B 1 210 ? 199.303 214.669 245.141 1.00 94.09  ? 210 LEU B CB  1 
ATOM   7791  C  CG  . LEU B 1 210 ? 200.397 215.622 245.621 1.00 93.13  ? 210 LEU B CG  1 
ATOM   7792  C  CD1 . LEU B 1 210 ? 200.446 215.569 247.130 1.00 87.50  ? 210 LEU B CD1 1 
ATOM   7793  C  CD2 . LEU B 1 210 ? 201.759 215.274 245.054 1.00 93.76  ? 210 LEU B CD2 1 
ATOM   7794  N  N   . TRP B 1 211 ? 197.773 211.742 244.485 1.00 86.63  ? 211 TRP B N   1 
ATOM   7795  C  CA  . TRP B 1 211 ? 196.614 210.907 244.750 1.00 87.68  ? 211 TRP B CA  1 
ATOM   7796  C  C   . TRP B 1 211 ? 196.908 209.425 244.573 1.00 82.23  ? 211 TRP B C   1 
ATOM   7797  O  O   . TRP B 1 211 ? 196.007 208.602 244.753 1.00 83.65  ? 211 TRP B O   1 
ATOM   7798  C  CB  . TRP B 1 211 ? 195.450 211.339 243.861 1.00 94.66  ? 211 TRP B CB  1 
ATOM   7799  C  CG  . TRP B 1 211 ? 194.583 212.369 244.519 1.00 97.58  ? 211 TRP B CG  1 
ATOM   7800  C  CD1 . TRP B 1 211 ? 194.442 213.675 244.150 1.00 94.88  ? 211 TRP B CD1 1 
ATOM   7801  C  CD2 . TRP B 1 211 ? 193.750 212.185 245.670 1.00 95.18  ? 211 TRP B CD2 1 
ATOM   7802  N  NE1 . TRP B 1 211 ? 193.570 214.314 244.996 1.00 92.27  ? 211 TRP B NE1 1 
ATOM   7803  C  CE2 . TRP B 1 211 ? 193.130 213.421 245.937 1.00 92.73  ? 211 TRP B CE2 1 
ATOM   7804  C  CE3 . TRP B 1 211 ? 193.465 211.096 246.495 1.00 92.97  ? 211 TRP B CE3 1 
ATOM   7805  C  CZ2 . TRP B 1 211 ? 192.246 213.596 246.994 1.00 91.72  ? 211 TRP B CZ2 1 
ATOM   7806  C  CZ3 . TRP B 1 211 ? 192.588 211.273 247.543 1.00 96.32  ? 211 TRP B CZ3 1 
ATOM   7807  C  CH2 . TRP B 1 211 ? 191.988 212.513 247.784 1.00 95.80  ? 211 TRP B CH2 1 
ATOM   7808  N  N   . LYS B 1 212 ? 198.145 209.060 244.246 1.00 80.48  ? 212 LYS B N   1 
ATOM   7809  C  CA  . LYS B 1 212 ? 198.489 207.649 244.155 1.00 83.05  ? 212 LYS B CA  1 
ATOM   7810  C  C   . LYS B 1 212 ? 198.356 206.974 245.514 1.00 80.27  ? 212 LYS B C   1 
ATOM   7811  O  O   . LYS B 1 212 ? 198.721 207.531 246.551 1.00 84.98  ? 212 LYS B O   1 
ATOM   7812  C  CB  . LYS B 1 212 ? 199.910 207.466 243.629 1.00 84.69  ? 212 LYS B CB  1 
ATOM   7813  C  CG  . LYS B 1 212 ? 200.030 207.466 242.119 1.00 85.55  ? 212 LYS B CG  1 
ATOM   7814  C  CD  . LYS B 1 212 ? 199.454 206.189 241.518 1.00 87.49  ? 212 LYS B CD  1 
ATOM   7815  C  CE  . LYS B 1 212 ? 199.904 204.946 242.278 1.00 89.55  ? 212 LYS B CE  1 
ATOM   7816  N  NZ  . LYS B 1 212 ? 201.383 204.796 242.304 1.00 83.16  ? 212 LYS B NZ  1 
ATOM   7817  N  N   . THR B 1 213 ? 197.824 205.756 245.496 1.00 76.18  ? 213 THR B N   1 
ATOM   7818  C  CA  . THR B 1 213 ? 197.535 205.012 246.714 1.00 77.67  ? 213 THR B CA  1 
ATOM   7819  C  C   . THR B 1 213 ? 198.720 204.207 247.218 1.00 73.28  ? 213 THR B C   1 
ATOM   7820  O  O   . THR B 1 213 ? 198.889 204.069 248.432 1.00 67.38  ? 213 THR B O   1 
ATOM   7821  C  CB  . THR B 1 213 ? 196.343 204.072 246.483 1.00 89.71  ? 213 THR B CB  1 
ATOM   7822  O  OG1 . THR B 1 213 ? 195.175 204.847 246.183 1.00 98.25  ? 213 THR B OG1 1 
ATOM   7823  C  CG2 . THR B 1 213 ? 196.063 203.227 247.717 1.00 85.27  ? 213 THR B CG2 1 
ATOM   7824  N  N   . ALA B 1 214 ? 199.543 203.674 246.323 1.00 76.14  ? 214 ALA B N   1 
ATOM   7825  C  CA  . ALA B 1 214 ? 200.702 202.896 246.721 1.00 77.94  ? 214 ALA B CA  1 
ATOM   7826  C  C   . ALA B 1 214 ? 201.952 203.773 246.712 1.00 76.25  ? 214 ALA B C   1 
ATOM   7827  O  O   . ALA B 1 214 ? 201.910 204.957 246.374 1.00 78.86  ? 214 ALA B O   1 
ATOM   7828  C  CB  . ALA B 1 214 ? 200.867 201.683 245.807 1.00 78.10  ? 214 ALA B CB  1 
ATOM   7829  N  N   . ARG B 1 215 ? 203.081 203.186 247.097 1.00 67.38  ? 215 ARG B N   1 
ATOM   7830  C  CA  . ARG B 1 215 ? 204.338 203.915 247.073 1.00 61.08  ? 215 ARG B CA  1 
ATOM   7831  C  C   . ARG B 1 215 ? 204.679 204.314 245.648 1.00 64.70  ? 215 ARG B C   1 
ATOM   7832  O  O   . ARG B 1 215 ? 204.599 203.496 244.728 1.00 71.88  ? 215 ARG B O   1 
ATOM   7833  C  CB  . ARG B 1 215 ? 205.453 203.061 247.663 1.00 60.64  ? 215 ARG B CB  1 
ATOM   7834  C  CG  . ARG B 1 215 ? 206.829 203.670 247.520 1.00 64.03  ? 215 ARG B CG  1 
ATOM   7835  C  CD  . ARG B 1 215 ? 207.603 203.023 246.390 1.00 69.66  ? 215 ARG B CD  1 
ATOM   7836  N  NE  . ARG B 1 215 ? 209.031 203.286 246.490 1.00 69.56  ? 215 ARG B NE  1 
ATOM   7837  C  CZ  . ARG B 1 215 ? 209.618 204.415 246.123 1.00 71.19  ? 215 ARG B CZ  1 
ATOM   7838  N  NH1 . ARG B 1 215 ? 208.926 205.419 245.610 1.00 70.70  ? 215 ARG B NH1 1 
ATOM   7839  N  NH2 . ARG B 1 215 ? 210.932 204.540 246.272 1.00 72.25  ? 215 ARG B NH2 1 
ATOM   7840  N  N   . ASP B 1 216 ? 205.066 205.569 245.462 1.00 59.78  ? 216 ASP B N   1 
ATOM   7841  C  CA  . ASP B 1 216 ? 205.330 206.066 244.120 1.00 62.44  ? 216 ASP B CA  1 
ATOM   7842  C  C   . ASP B 1 216 ? 206.269 207.252 244.222 1.00 62.27  ? 216 ASP B C   1 
ATOM   7843  O  O   . ASP B 1 216 ? 206.531 207.769 245.308 1.00 70.38  ? 216 ASP B O   1 
ATOM   7844  C  CB  . ASP B 1 216 ? 204.039 206.456 243.402 1.00 73.39  ? 216 ASP B CB  1 
ATOM   7845  C  CG  . ASP B 1 216 ? 204.171 206.395 241.892 1.00 82.88  ? 216 ASP B CG  1 
ATOM   7846  O  OD1 . ASP B 1 216 ? 205.316 206.343 241.397 1.00 82.26  ? 216 ASP B OD1 1 
ATOM   7847  O  OD2 . ASP B 1 216 ? 203.130 206.401 241.201 1.00 87.34  ? 216 ASP B OD2 1 
ATOM   7848  N  N   . GLN B 1 217 ? 206.778 207.678 243.074 1.00 59.00  ? 217 GLN B N   1 
ATOM   7849  C  CA  . GLN B 1 217 ? 207.653 208.833 243.047 1.00 64.00  ? 217 GLN B CA  1 
ATOM   7850  C  C   . GLN B 1 217 ? 207.656 209.412 241.644 1.00 69.74  ? 217 GLN B C   1 
ATOM   7851  O  O   . GLN B 1 217 ? 207.249 208.759 240.681 1.00 74.63  ? 217 GLN B O   1 
ATOM   7852  C  CB  . GLN B 1 217 ? 209.068 208.466 243.498 1.00 67.09  ? 217 GLN B CB  1 
ATOM   7853  C  CG  . GLN B 1 217 ? 209.877 207.747 242.451 1.00 73.70  ? 217 GLN B CG  1 
ATOM   7854  C  CD  . GLN B 1 217 ? 211.351 207.752 242.769 1.00 74.98  ? 217 GLN B CD  1 
ATOM   7855  O  OE1 . GLN B 1 217 ? 211.746 207.813 243.930 1.00 71.46  ? 217 GLN B OE1 1 
ATOM   7856  N  NE2 . GLN B 1 217 ? 212.178 207.705 241.735 1.00 76.00  ? 217 GLN B NE2 1 
ATOM   7857  N  N   . ASP B 1 218 ? 208.115 210.654 241.541 1.00 71.60  ? 218 ASP B N   1 
ATOM   7858  C  CA  . ASP B 1 218 ? 208.155 211.345 240.260 1.00 78.82  ? 218 ASP B CA  1 
ATOM   7859  C  C   . ASP B 1 218 ? 209.102 212.530 240.365 1.00 79.13  ? 218 ASP B C   1 
ATOM   7860  O  O   . ASP B 1 218 ? 209.630 212.836 241.436 1.00 79.13  ? 218 ASP B O   1 
ATOM   7861  C  CB  . ASP B 1 218 ? 206.759 211.800 239.832 1.00 85.87  ? 218 ASP B CB  1 
ATOM   7862  C  CG  . ASP B 1 218 ? 206.597 211.841 238.326 1.00 94.17  ? 218 ASP B CG  1 
ATOM   7863  O  OD1 . ASP B 1 218 ? 207.604 211.646 237.613 1.00 92.90  ? 218 ASP B OD1 1 
ATOM   7864  O  OD2 . ASP B 1 218 ? 205.464 212.062 237.857 1.00 97.13  ? 218 ASP B OD2 1 
ATOM   7865  N  N   . GLU B 1 219 ? 209.306 213.198 239.234 1.00 79.41  ? 219 GLU B N   1 
ATOM   7866  C  CA  . GLU B 1 219 ? 210.123 214.399 239.157 1.00 77.84  ? 219 GLU B CA  1 
ATOM   7867  C  C   . GLU B 1 219 ? 209.293 215.543 238.594 1.00 80.81  ? 219 GLU B C   1 
ATOM   7868  O  O   . GLU B 1 219 ? 208.512 215.352 237.659 1.00 83.71  ? 219 GLU B O   1 
ATOM   7869  C  CB  . GLU B 1 219 ? 211.371 214.192 238.288 1.00 78.17  ? 219 GLU B CB  1 
ATOM   7870  C  CG  . GLU B 1 219 ? 212.205 212.946 238.577 1.00 78.06  ? 219 GLU B CG  1 
ATOM   7871  C  CD  . GLU B 1 219 ? 211.493 211.640 238.273 1.00 83.73  ? 219 GLU B CD  1 
ATOM   7872  O  OE1 . GLU B 1 219 ? 210.511 211.659 237.503 1.00 85.33  ? 219 GLU B OE1 1 
ATOM   7873  O  OE2 . GLU B 1 219 ? 211.919 210.593 238.804 1.00 82.20  ? 219 GLU B OE2 1 
ATOM   7874  N  N   . PHE B 1 220 ? 209.466 216.732 239.165 1.00 83.78  ? 220 PHE B N   1 
ATOM   7875  C  CA  . PHE B 1 220 ? 208.719 217.909 238.752 1.00 89.37  ? 220 PHE B CA  1 
ATOM   7876  C  C   . PHE B 1 220 ? 209.641 219.116 238.633 1.00 96.61  ? 220 PHE B C   1 
ATOM   7877  O  O   . PHE B 1 220 ? 210.732 219.158 239.206 1.00 96.58  ? 220 PHE B O   1 
ATOM   7878  C  CB  . PHE B 1 220 ? 207.594 218.243 239.737 1.00 86.20  ? 220 PHE B CB  1 
ATOM   7879  C  CG  . PHE B 1 220 ? 206.699 217.095 240.043 1.00 79.47  ? 220 PHE B CG  1 
ATOM   7880  C  CD1 . PHE B 1 220 ? 206.040 216.429 239.036 1.00 87.31  ? 220 PHE B CD1 1 
ATOM   7881  C  CD2 . PHE B 1 220 ? 206.503 216.695 241.343 1.00 81.26  ? 220 PHE B CD2 1 
ATOM   7882  C  CE1 . PHE B 1 220 ? 205.210 215.374 239.323 1.00 93.35  ? 220 PHE B CE1 1 
ATOM   7883  C  CE2 . PHE B 1 220 ? 205.678 215.640 241.634 1.00 85.28  ? 220 PHE B CE2 1 
ATOM   7884  C  CZ  . PHE B 1 220 ? 205.030 214.979 240.626 1.00 91.21  ? 220 PHE B CZ  1 
ATOM   7885  N  N   . LEU B 1 221 ? 209.181 220.101 237.866 1.00 97.95  ? 221 LEU B N   1 
ATOM   7886  C  CA  . LEU B 1 221 ? 209.753 221.441 237.850 1.00 95.87  ? 221 LEU B CA  1 
ATOM   7887  C  C   . LEU B 1 221 ? 208.786 222.376 238.564 1.00 100.17 ? 221 LEU B C   1 
ATOM   7888  O  O   . LEU B 1 221 ? 207.599 222.421 238.226 1.00 101.55 ? 221 LEU B O   1 
ATOM   7889  C  CB  . LEU B 1 221 ? 210.002 221.911 236.416 1.00 99.69  ? 221 LEU B CB  1 
ATOM   7890  C  CG  . LEU B 1 221 ? 210.301 223.395 236.190 1.00 109.36 ? 221 LEU B CG  1 
ATOM   7891  C  CD1 . LEU B 1 221 ? 211.757 223.712 236.489 1.00 106.78 ? 221 LEU B CD1 1 
ATOM   7892  C  CD2 . LEU B 1 221 ? 209.944 223.800 234.768 1.00 110.46 ? 221 LEU B CD2 1 
ATOM   7893  N  N   . LEU B 1 222 ? 209.287 223.112 239.551 1.00 101.13 ? 222 LEU B N   1 
ATOM   7894  C  CA  . LEU B 1 222 ? 208.439 223.900 240.429 1.00 104.69 ? 222 LEU B CA  1 
ATOM   7895  C  C   . LEU B 1 222 ? 208.989 225.307 240.605 1.00 109.91 ? 222 LEU B C   1 
ATOM   7896  O  O   . LEU B 1 222 ? 210.154 225.596 240.307 1.00 111.55 ? 222 LEU B O   1 
ATOM   7897  C  CB  . LEU B 1 222 ? 208.284 223.236 241.798 1.00 105.73 ? 222 LEU B CB  1 
ATOM   7898  C  CG  . LEU B 1 222 ? 207.502 221.925 241.807 1.00 107.36 ? 222 LEU B CG  1 
ATOM   7899  C  CD1 . LEU B 1 222 ? 207.341 221.417 243.226 1.00 108.39 ? 222 LEU B CD1 1 
ATOM   7900  C  CD2 . LEU B 1 222 ? 206.148 222.117 241.146 1.00 105.98 ? 222 LEU B CD2 1 
ATOM   7901  N  N   . LEU B 1 223 ? 208.113 226.185 241.089 1.00 111.69 ? 223 LEU B N   1 
ATOM   7902  C  CA  . LEU B 1 223 ? 208.434 227.576 241.372 1.00 107.93 ? 223 LEU B CA  1 
ATOM   7903  C  C   . LEU B 1 223 ? 208.118 227.875 242.830 1.00 106.27 ? 223 LEU B C   1 
ATOM   7904  O  O   . LEU B 1 223 ? 207.009 227.602 243.299 1.00 104.48 ? 223 LEU B O   1 
ATOM   7905  C  CB  . LEU B 1 223 ? 207.644 228.515 240.460 1.00 107.37 ? 223 LEU B CB  1 
ATOM   7906  C  CG  . LEU B 1 223 ? 208.005 228.497 238.977 1.00 108.14 ? 223 LEU B CG  1 
ATOM   7907  C  CD1 . LEU B 1 223 ? 206.921 229.186 238.168 1.00 109.37 ? 223 LEU B CD1 1 
ATOM   7908  C  CD2 . LEU B 1 223 ? 209.336 229.178 238.767 1.00 109.04 ? 223 LEU B CD2 1 
ATOM   7909  N  N   . THR B 1 224 ? 209.083 228.450 243.536 1.00 107.02 ? 224 THR B N   1 
ATOM   7910  C  CA  . THR B 1 224 ? 208.903 228.774 244.943 1.00 108.39 ? 224 THR B CA  1 
ATOM   7911  C  C   . THR B 1 224 ? 208.063 230.040 245.064 1.00 110.06 ? 224 THR B C   1 
ATOM   7912  O  O   . THR B 1 224 ? 207.466 230.524 244.099 1.00 109.93 ? 224 THR B O   1 
ATOM   7913  C  CB  . THR B 1 224 ? 210.253 228.936 245.633 1.00 105.89 ? 224 THR B CB  1 
ATOM   7914  O  OG1 . THR B 1 224 ? 210.800 230.222 245.316 1.00 109.46 ? 224 THR B OG1 1 
ATOM   7915  C  CG2 . THR B 1 224 ? 211.219 227.857 245.175 1.00 103.29 ? 224 THR B CG2 1 
ATOM   7916  N  N   . ARG B 1 225 ? 208.004 230.591 246.275 1.00 109.30 ? 225 ARG B N   1 
ATOM   7917  C  CA  . ARG B 1 225 ? 207.358 231.880 246.467 1.00 113.21 ? 225 ARG B CA  1 
ATOM   7918  C  C   . ARG B 1 225 ? 208.201 233.037 245.947 1.00 116.69 ? 225 ARG B C   1 
ATOM   7919  O  O   . ARG B 1 225 ? 207.676 234.147 245.804 1.00 116.26 ? 225 ARG B O   1 
ATOM   7920  C  CB  . ARG B 1 225 ? 207.040 232.086 247.946 1.00 110.49 ? 225 ARG B CB  1 
ATOM   7921  C  CG  . ARG B 1 225 ? 205.695 232.734 248.203 1.00 114.90 ? 225 ARG B CG  1 
ATOM   7922  C  CD  . ARG B 1 225 ? 205.500 233.024 249.682 1.00 115.65 ? 225 ARG B CD  1 
ATOM   7923  N  NE  . ARG B 1 225 ? 204.150 233.488 249.975 1.00 121.25 ? 225 ARG B NE  1 
ATOM   7924  C  CZ  . ARG B 1 225 ? 203.718 233.823 251.183 1.00 121.81 ? 225 ARG B CZ  1 
ATOM   7925  N  NH1 . ARG B 1 225 ? 204.508 233.759 252.242 1.00 119.41 ? 225 ARG B NH1 1 
ATOM   7926  N  NH2 . ARG B 1 225 ? 202.462 234.233 251.332 1.00 122.74 ? 225 ARG B NH2 1 
ATOM   7927  N  N   . THR B 1 226 ? 209.483 232.810 245.663 1.00 117.41 ? 226 THR B N   1 
ATOM   7928  C  CA  . THR B 1 226 ? 210.358 233.834 245.107 1.00 115.49 ? 226 THR B CA  1 
ATOM   7929  C  C   . THR B 1 226 ? 210.417 233.803 243.587 1.00 113.44 ? 226 THR B C   1 
ATOM   7930  O  O   . THR B 1 226 ? 211.126 234.621 242.993 1.00 110.83 ? 226 THR B O   1 
ATOM   7931  C  CB  . THR B 1 226 ? 211.777 233.690 245.667 1.00 114.67 ? 226 THR B CB  1 
ATOM   7932  O  OG1 . THR B 1 226 ? 212.332 232.438 245.251 1.00 115.16 ? 226 THR B OG1 1 
ATOM   7933  C  CG2 . THR B 1 226 ? 211.759 233.753 247.186 1.00 109.83 ? 226 THR B CG2 1 
ATOM   7934  N  N   . GLY B 1 227 ? 209.697 232.887 242.946 1.00 114.60 ? 227 GLY B N   1 
ATOM   7935  C  CA  . GLY B 1 227 ? 209.657 232.830 241.501 1.00 113.99 ? 227 GLY B CA  1 
ATOM   7936  C  C   . GLY B 1 227 ? 210.804 232.096 240.846 1.00 109.46 ? 227 GLY B C   1 
ATOM   7937  O  O   . GLY B 1 227 ? 210.925 232.144 239.617 1.00 109.44 ? 227 GLY B O   1 
ATOM   7938  N  N   . GLU B 1 228 ? 211.646 231.420 241.618 1.00 106.73 ? 228 GLU B N   1 
ATOM   7939  C  CA  . GLU B 1 228 ? 212.780 230.707 241.056 1.00 107.45 ? 228 GLU B CA  1 
ATOM   7940  C  C   . GLU B 1 228 ? 212.349 229.349 240.512 1.00 110.72 ? 228 GLU B C   1 
ATOM   7941  O  O   . GLU B 1 228 ? 211.479 228.677 241.072 1.00 107.33 ? 228 GLU B O   1 
ATOM   7942  C  CB  . GLU B 1 228 ? 213.874 230.534 242.110 1.00 106.79 ? 228 GLU B CB  1 
ATOM   7943  C  CG  . GLU B 1 228 ? 215.074 229.740 241.639 1.00 109.74 ? 228 GLU B CG  1 
ATOM   7944  C  CD  . GLU B 1 228 ? 215.660 230.282 240.352 1.00 116.84 ? 228 GLU B CD  1 
ATOM   7945  O  OE1 . GLU B 1 228 ? 216.402 231.285 240.409 1.00 121.83 ? 228 GLU B OE1 1 
ATOM   7946  O  OE2 . GLU B 1 228 ? 215.376 229.705 239.280 1.00 118.21 ? 228 GLU B OE2 1 
ATOM   7947  N  N   . LYS B 1 229 ? 212.956 228.963 239.389 1.00 114.74 ? 229 LYS B N   1 
ATOM   7948  C  CA  . LYS B 1 229 ? 212.738 227.655 238.784 1.00 111.24 ? 229 LYS B CA  1 
ATOM   7949  C  C   . LYS B 1 229 ? 213.653 226.625 239.435 1.00 109.93 ? 229 LYS B C   1 
ATOM   7950  O  O   . LYS B 1 229 ? 214.869 226.831 239.510 1.00 108.96 ? 229 LYS B O   1 
ATOM   7951  C  CB  . LYS B 1 229 ? 212.999 227.706 237.278 1.00 109.89 ? 229 LYS B CB  1 
ATOM   7952  C  CG  . LYS B 1 229 ? 211.815 228.175 236.453 1.00 110.00 ? 229 LYS B CG  1 
ATOM   7953  C  CD  . LYS B 1 229 ? 212.178 228.334 234.986 1.00 108.84 ? 229 LYS B CD  1 
ATOM   7954  C  CE  . LYS B 1 229 ? 210.982 228.811 234.177 1.00 112.00 ? 229 LYS B CE  1 
ATOM   7955  N  NZ  . LYS B 1 229 ? 211.316 228.994 232.738 1.00 109.93 ? 229 LYS B NZ  1 
ATOM   7956  N  N   . ILE B 1 230 ? 213.068 225.519 239.904 1.00 108.35 ? 230 ILE B N   1 
ATOM   7957  C  CA  . ILE B 1 230 ? 213.826 224.431 240.511 1.00 101.88 ? 230 ILE B CA  1 
ATOM   7958  C  C   . ILE B 1 230 ? 213.281 223.103 240.006 1.00 98.16  ? 230 ILE B C   1 
ATOM   7959  O  O   . ILE B 1 230 ? 212.136 223.003 239.569 1.00 100.78 ? 230 ILE B O   1 
ATOM   7960  C  CB  . ILE B 1 230 ? 213.767 224.476 242.051 1.00 98.95  ? 230 ILE B CB  1 
ATOM   7961  C  CG1 . ILE B 1 230 ? 212.352 224.829 242.510 1.00 100.79 ? 230 ILE B CG1 1 
ATOM   7962  C  CG2 . ILE B 1 230 ? 214.776 225.474 242.594 1.00 99.61  ? 230 ILE B CG2 1 
ATOM   7963  C  CD1 . ILE B 1 230 ? 212.099 224.547 243.968 1.00 94.86  ? 230 ILE B CD1 1 
ATOM   7964  N  N   . TRP B 1 231 ? 214.117 222.074 240.075 1.00 93.52  ? 231 TRP B N   1 
ATOM   7965  C  CA  . TRP B 1 231 ? 213.712 220.712 239.754 1.00 93.91  ? 231 TRP B CA  1 
ATOM   7966  C  C   . TRP B 1 231 ? 213.788 219.847 241.006 1.00 90.61  ? 231 TRP B C   1 
ATOM   7967  O  O   . TRP B 1 231 ? 214.842 219.765 241.646 1.00 89.92  ? 231 TRP B O   1 
ATOM   7968  C  CB  . TRP B 1 231 ? 214.586 220.132 238.643 1.00 89.46  ? 231 TRP B CB  1 
ATOM   7969  C  CG  . TRP B 1 231 ? 214.165 220.532 237.258 1.00 90.14  ? 231 TRP B CG  1 
ATOM   7970  C  CD1 . TRP B 1 231 ? 214.707 221.517 236.494 1.00 93.38  ? 231 TRP B CD1 1 
ATOM   7971  C  CD2 . TRP B 1 231 ? 213.153 219.912 236.452 1.00 86.70  ? 231 TRP B CD2 1 
ATOM   7972  N  NE1 . TRP B 1 231 ? 214.080 221.570 235.277 1.00 91.67  ? 231 TRP B NE1 1 
ATOM   7973  C  CE2 . TRP B 1 231 ? 213.126 220.591 235.226 1.00 89.13  ? 231 TRP B CE2 1 
ATOM   7974  C  CE3 . TRP B 1 231 ? 212.271 218.852 236.653 1.00 86.71  ? 231 TRP B CE3 1 
ATOM   7975  C  CZ2 . TRP B 1 231 ? 212.248 220.250 234.205 1.00 92.23  ? 231 TRP B CZ2 1 
ATOM   7976  C  CZ3 . TRP B 1 231 ? 211.399 218.514 235.640 1.00 88.65  ? 231 TRP B CZ3 1 
ATOM   7977  C  CH2 . TRP B 1 231 ? 211.394 219.209 234.431 1.00 91.18  ? 231 TRP B CH2 1 
ATOM   7978  N  N   . ILE B 1 232 ? 212.671 219.202 241.353 1.00 85.35  ? 232 ILE B N   1 
ATOM   7979  C  CA  . ILE B 1 232 ? 212.572 218.414 242.571 1.00 78.80  ? 232 ILE B CA  1 
ATOM   7980  C  C   . ILE B 1 232 ? 212.111 217.001 242.243 1.00 79.21  ? 232 ILE B C   1 
ATOM   7981  O  O   . ILE B 1 232 ? 211.590 216.721 241.161 1.00 81.74  ? 232 ILE B O   1 
ATOM   7982  C  CB  . ILE B 1 232 ? 211.615 219.037 243.603 1.00 77.55  ? 232 ILE B CB  1 
ATOM   7983  C  CG1 . ILE B 1 232 ? 210.187 218.585 243.328 1.00 77.37  ? 232 ILE B CG1 1 
ATOM   7984  C  CG2 . ILE B 1 232 ? 211.701 220.543 243.572 1.00 84.81  ? 232 ILE B CG2 1 
ATOM   7985  C  CD1 . ILE B 1 232 ? 209.291 218.689 244.527 1.00 75.67  ? 232 ILE B CD1 1 
ATOM   7986  N  N   . LYS B 1 233 ? 212.311 216.108 243.212 1.00 75.72  ? 233 LYS B N   1 
ATOM   7987  C  CA  . LYS B 1 233 ? 211.848 214.728 243.148 1.00 65.57  ? 233 LYS B CA  1 
ATOM   7988  C  C   . LYS B 1 233 ? 210.945 214.468 244.338 1.00 57.87  ? 233 LYS B C   1 
ATOM   7989  O  O   . LYS B 1 233 ? 211.365 214.631 245.486 1.00 59.81  ? 233 LYS B O   1 
ATOM   7990  C  CB  . LYS B 1 233 ? 213.018 213.753 243.150 1.00 67.12  ? 233 LYS B CB  1 
ATOM   7991  C  CG  . LYS B 1 233 ? 212.641 212.371 243.604 1.00 68.99  ? 233 LYS B CG  1 
ATOM   7992  C  CD  . LYS B 1 233 ? 213.807 211.432 243.430 1.00 72.60  ? 233 LYS B CD  1 
ATOM   7993  C  CE  . LYS B 1 233 ? 213.882 210.983 241.984 1.00 74.10  ? 233 LYS B CE  1 
ATOM   7994  N  NZ  . LYS B 1 233 ? 215.213 210.416 241.663 1.00 73.96  ? 233 LYS B NZ  1 
ATOM   7995  N  N   . ALA B 1 234 ? 209.715 214.064 244.068 1.00 57.52  ? 234 ALA B N   1 
ATOM   7996  C  CA  . ALA B 1 234 ? 208.707 213.919 245.106 1.00 59.87  ? 234 ALA B CA  1 
ATOM   7997  C  C   . ALA B 1 234 ? 208.296 212.463 245.218 1.00 60.21  ? 234 ALA B C   1 
ATOM   7998  O  O   . ALA B 1 234 ? 208.012 211.814 244.206 1.00 66.61  ? 234 ALA B O   1 
ATOM   7999  C  CB  . ALA B 1 234 ? 207.488 214.795 244.816 1.00 67.69  ? 234 ALA B CB  1 
ATOM   8000  N  N   . SER B 1 235 ? 208.249 211.961 246.447 1.00 55.03  ? 235 SER B N   1 
ATOM   8001  C  CA  . SER B 1 235 ? 207.958 210.565 246.720 1.00 55.36  ? 235 SER B CA  1 
ATOM   8002  C  C   . SER B 1 235 ? 206.829 210.457 247.727 1.00 52.08  ? 235 SER B C   1 
ATOM   8003  O  O   . SER B 1 235 ? 206.820 211.157 248.739 1.00 57.24  ? 235 SER B O   1 
ATOM   8004  C  CB  . SER B 1 235 ? 209.191 209.846 247.253 1.00 59.18  ? 235 SER B CB  1 
ATOM   8005  O  OG  . SER B 1 235 ? 208.832 208.640 247.899 1.00 61.25  ? 235 SER B OG  1 
ATOM   8006  N  N   . ILE B 1 236 ? 205.878 209.580 247.438 1.00 51.29  ? 236 ILE B N   1 
ATOM   8007  C  CA  . ILE B 1 236 ? 204.780 209.255 248.334 1.00 53.19  ? 236 ILE B CA  1 
ATOM   8008  C  C   . ILE B 1 236 ? 204.973 207.837 248.842 1.00 57.72  ? 236 ILE B C   1 
ATOM   8009  O  O   . ILE B 1 236 ? 205.315 206.928 248.073 1.00 67.21  ? 236 ILE B O   1 
ATOM   8010  C  CB  . ILE B 1 236 ? 203.410 209.426 247.648 1.00 61.71  ? 236 ILE B CB  1 
ATOM   8011  C  CG1 . ILE B 1 236 ? 202.281 209.479 248.680 1.00 61.63  ? 236 ILE B CG1 1 
ATOM   8012  C  CG2 . ILE B 1 236 ? 203.154 208.349 246.603 1.00 68.09  ? 236 ILE B CG2 1 
ATOM   8013  C  CD1 . ILE B 1 236 ? 202.321 210.637 249.598 1.00 57.30  ? 236 ILE B CD1 1 
ATOM   8014  N  N   . SER B 1 237 ? 204.797 207.665 250.134 1.00 52.04  ? 237 SER B N   1 
ATOM   8015  C  CA  . SER B 1 237 ? 204.765 206.362 250.765 1.00 53.96  ? 237 SER B CA  1 
ATOM   8016  C  C   . SER B 1 237 ? 203.762 206.440 251.900 1.00 54.37  ? 237 SER B C   1 
ATOM   8017  O  O   . SER B 1 237 ? 204.014 207.126 252.897 1.00 61.82  ? 237 SER B O   1 
ATOM   8018  C  CB  . SER B 1 237 ? 206.145 205.965 251.278 1.00 57.79  ? 237 SER B CB  1 
ATOM   8019  O  OG  . SER B 1 237 ? 207.101 206.015 250.236 1.00 66.02  ? 237 SER B OG  1 
ATOM   8020  N  N   . PRO B 1 238 ? 202.622 205.778 251.794 1.00 55.07  ? 238 PRO B N   1 
ATOM   8021  C  CA  . PRO B 1 238 ? 201.574 205.927 252.802 1.00 58.28  ? 238 PRO B CA  1 
ATOM   8022  C  C   . PRO B 1 238 ? 201.803 204.980 253.971 1.00 58.53  ? 238 PRO B C   1 
ATOM   8023  O  O   . PRO B 1 238 ? 202.610 204.053 253.909 1.00 61.42  ? 238 PRO B O   1 
ATOM   8024  C  CB  . PRO B 1 238 ? 200.299 205.553 252.040 1.00 62.68  ? 238 PRO B CB  1 
ATOM   8025  C  CG  . PRO B 1 238 ? 200.771 204.734 250.849 1.00 67.51  ? 238 PRO B CG  1 
ATOM   8026  C  CD  . PRO B 1 238 ? 202.275 204.756 250.799 1.00 63.42  ? 238 PRO B CD  1 
ATOM   8027  N  N   . VAL B 1 239 ? 201.068 205.235 255.046 1.00 58.00  ? 239 VAL B N   1 
ATOM   8028  C  CA  . VAL B 1 239 ? 201.129 204.416 256.244 1.00 63.34  ? 239 VAL B CA  1 
ATOM   8029  C  C   . VAL B 1 239 ? 199.712 204.071 256.682 1.00 74.20  ? 239 VAL B C   1 
ATOM   8030  O  O   . VAL B 1 239 ? 198.803 204.911 256.628 1.00 78.40  ? 239 VAL B O   1 
ATOM   8031  C  CB  . VAL B 1 239 ? 201.911 205.122 257.368 1.00 58.76  ? 239 VAL B CB  1 
ATOM   8032  C  CG1 . VAL B 1 239 ? 201.313 206.475 257.660 1.00 60.81  ? 239 VAL B CG1 1 
ATOM   8033  C  CG2 . VAL B 1 239 ? 201.947 204.264 258.621 1.00 65.43  ? 239 VAL B CG2 1 
ATOM   8034  N  N   . TYR B 1 240 ? 199.517 202.819 257.086 1.00 75.42  ? 240 TYR B N   1 
ATOM   8035  C  CA  . TYR B 1 240 ? 198.231 202.345 257.561 1.00 78.35  ? 240 TYR B CA  1 
ATOM   8036  C  C   . TYR B 1 240 ? 198.325 201.933 259.021 1.00 81.49  ? 240 TYR B C   1 
ATOM   8037  O  O   . TYR B 1 240 ? 199.361 201.452 259.486 1.00 77.72  ? 240 TYR B O   1 
ATOM   8038  C  CB  . TYR B 1 240 ? 197.722 201.171 256.727 1.00 78.74  ? 240 TYR B CB  1 
ATOM   8039  C  CG  . TYR B 1 240 ? 197.868 201.382 255.250 1.00 71.81  ? 240 TYR B CG  1 
ATOM   8040  C  CD1 . TYR B 1 240 ? 196.981 202.191 254.565 1.00 72.44  ? 240 TYR B CD1 1 
ATOM   8041  C  CD2 . TYR B 1 240 ? 198.877 200.765 254.536 1.00 71.11  ? 240 TYR B CD2 1 
ATOM   8042  C  CE1 . TYR B 1 240 ? 197.098 202.395 253.219 1.00 74.97  ? 240 TYR B CE1 1 
ATOM   8043  C  CE2 . TYR B 1 240 ? 199.005 200.959 253.178 1.00 75.03  ? 240 TYR B CE2 1 
ATOM   8044  C  CZ  . TYR B 1 240 ? 198.109 201.775 252.523 1.00 78.17  ? 240 TYR B CZ  1 
ATOM   8045  O  OH  . TYR B 1 240 ? 198.227 201.976 251.167 1.00 79.19  ? 240 TYR B OH  1 
ATOM   8046  N  N   . ASP B 1 241 ? 197.218 202.112 259.729 1.00 86.26  ? 241 ASP B N   1 
ATOM   8047  C  CA  . ASP B 1 241 ? 197.133 201.763 261.138 1.00 93.33  ? 241 ASP B CA  1 
ATOM   8048  C  C   . ASP B 1 241 ? 197.043 200.243 261.271 1.00 97.22  ? 241 ASP B C   1 
ATOM   8049  O  O   . ASP B 1 241 ? 197.242 199.491 260.313 1.00 97.61  ? 241 ASP B O   1 
ATOM   8050  C  CB  . ASP B 1 241 ? 195.944 202.469 261.779 1.00 94.83  ? 241 ASP B CB  1 
ATOM   8051  C  CG  . ASP B 1 241 ? 196.186 202.815 263.235 1.00 95.83  ? 241 ASP B CG  1 
ATOM   8052  O  OD1 . ASP B 1 241 ? 197.290 202.524 263.741 1.00 94.27  ? 241 ASP B OD1 1 
ATOM   8053  O  OD2 . ASP B 1 241 ? 195.272 203.377 263.874 1.00 95.33  ? 241 ASP B OD2 1 
ATOM   8054  N  N   . VAL B 1 242 ? 196.749 199.772 262.485 1.00 99.18  ? 242 VAL B N   1 
ATOM   8055  C  CA  . VAL B 1 242 ? 196.663 198.333 262.724 1.00 99.29  ? 242 VAL B CA  1 
ATOM   8056  C  C   . VAL B 1 242 ? 195.536 197.720 261.904 1.00 96.84  ? 242 VAL B C   1 
ATOM   8057  O  O   . VAL B 1 242 ? 195.706 196.666 261.281 1.00 91.94  ? 242 VAL B O   1 
ATOM   8058  C  CB  . VAL B 1 242 ? 196.485 198.049 264.226 1.00 99.83  ? 242 VAL B CB  1 
ATOM   8059  C  CG1 . VAL B 1 242 ? 196.440 196.551 264.479 1.00 96.45  ? 242 VAL B CG1 1 
ATOM   8060  C  CG2 . VAL B 1 242 ? 197.604 198.698 265.024 1.00 98.96  ? 242 VAL B CG2 1 
ATOM   8061  N  N   . LEU B 1 243 ? 194.378 198.372 261.877 1.00 97.66  ? 243 LEU B N   1 
ATOM   8062  C  CA  . LEU B 1 243 ? 193.213 197.837 261.187 1.00 95.53  ? 243 LEU B CA  1 
ATOM   8063  C  C   . LEU B 1 243 ? 193.256 198.082 259.685 1.00 91.85  ? 243 LEU B C   1 
ATOM   8064  O  O   . LEU B 1 243 ? 192.242 197.887 259.008 1.00 93.66  ? 243 LEU B O   1 
ATOM   8065  C  CB  . LEU B 1 243 ? 191.934 198.411 261.815 1.00 94.90  ? 243 LEU B CB  1 
ATOM   8066  C  CG  . LEU B 1 243 ? 191.419 199.834 261.576 1.00 95.11  ? 243 LEU B CG  1 
ATOM   8067  C  CD1 . LEU B 1 243 ? 190.477 199.911 260.390 1.00 91.29  ? 243 LEU B CD1 1 
ATOM   8068  C  CD2 . LEU B 1 243 ? 190.744 200.368 262.830 1.00 97.88  ? 243 LEU B CD2 1 
ATOM   8069  N  N   . ALA B 1 244 ? 194.407 198.487 259.158 1.00 88.16  ? 244 ALA B N   1 
ATOM   8070  C  CA  . ALA B 1 244 ? 194.726 198.633 257.742 1.00 87.71  ? 244 ALA B CA  1 
ATOM   8071  C  C   . ALA B 1 244 ? 194.062 199.846 257.098 1.00 89.44  ? 244 ALA B C   1 
ATOM   8072  O  O   . ALA B 1 244 ? 194.230 200.040 255.889 1.00 90.81  ? 244 ALA B O   1 
ATOM   8073  C  CB  . ALA B 1 244 ? 194.375 197.384 256.917 1.00 85.55  ? 244 ALA B CB  1 
ATOM   8074  N  N   . HIS B 1 245 ? 193.323 200.664 257.841 1.00 89.62  ? 245 HIS B N   1 
ATOM   8075  C  CA  . HIS B 1 245 ? 192.841 201.918 257.281 1.00 93.54  ? 245 HIS B CA  1 
ATOM   8076  C  C   . HIS B 1 245 ? 193.990 202.905 257.112 1.00 94.08  ? 245 HIS B C   1 
ATOM   8077  O  O   . HIS B 1 245 ? 194.911 202.959 257.931 1.00 92.98  ? 245 HIS B O   1 
ATOM   8078  C  CB  . HIS B 1 245 ? 191.758 202.523 258.166 1.00 93.22  ? 245 HIS B CB  1 
ATOM   8079  C  CG  . HIS B 1 245 ? 190.378 202.052 257.834 1.00 100.76 ? 245 HIS B CG  1 
ATOM   8080  N  ND1 . HIS B 1 245 ? 189.244 202.704 258.270 1.00 108.51 ? 245 HIS B ND1 1 
ATOM   8081  C  CD2 . HIS B 1 245 ? 189.947 200.999 257.100 1.00 102.73 ? 245 HIS B CD2 1 
ATOM   8082  C  CE1 . HIS B 1 245 ? 188.175 202.069 257.824 1.00 109.27 ? 245 HIS B CE1 1 
ATOM   8083  N  NE2 . HIS B 1 245 ? 188.574 201.031 257.112 1.00 106.77 ? 245 HIS B NE2 1 
ATOM   8084  N  N   . LEU B 1 246 ? 193.928 203.690 256.035 1.00 89.94  ? 246 LEU B N   1 
ATOM   8085  C  CA  . LEU B 1 246 ? 194.954 204.679 255.728 1.00 82.93  ? 246 LEU B CA  1 
ATOM   8086  C  C   . LEU B 1 246 ? 195.029 205.746 256.809 1.00 83.68  ? 246 LEU B C   1 
ATOM   8087  O  O   . LEU B 1 246 ? 194.086 206.524 256.977 1.00 82.00  ? 246 LEU B O   1 
ATOM   8088  C  CB  . LEU B 1 246 ? 194.676 205.329 254.374 1.00 80.69  ? 246 LEU B CB  1 
ATOM   8089  C  CG  . LEU B 1 246 ? 195.555 206.527 254.023 1.00 82.49  ? 246 LEU B CG  1 
ATOM   8090  C  CD1 . LEU B 1 246 ? 196.987 206.078 253.813 1.00 79.58  ? 246 LEU B CD1 1 
ATOM   8091  C  CD2 . LEU B 1 246 ? 195.033 207.244 252.795 1.00 85.44  ? 246 LEU B CD2 1 
ATOM   8092  N  N   . GLN B 1 247 ? 196.137 205.801 257.551 1.00 83.85  ? 247 GLN B N   1 
ATOM   8093  C  CA  . GLN B 1 247 ? 196.239 206.773 258.633 1.00 82.57  ? 247 GLN B CA  1 
ATOM   8094  C  C   . GLN B 1 247 ? 196.795 208.101 258.130 1.00 83.85  ? 247 GLN B C   1 
ATOM   8095  O  O   . GLN B 1 247 ? 196.136 209.139 258.247 1.00 89.14  ? 247 GLN B O   1 
ATOM   8096  C  CB  . GLN B 1 247 ? 197.104 206.215 259.765 1.00 83.36  ? 247 GLN B CB  1 
ATOM   8097  C  CG  . GLN B 1 247 ? 196.548 206.502 261.144 1.00 86.57  ? 247 GLN B CG  1 
ATOM   8098  C  CD  . GLN B 1 247 ? 197.473 206.044 262.251 1.00 90.43  ? 247 GLN B CD  1 
ATOM   8099  O  OE1 . GLN B 1 247 ? 198.507 205.427 261.997 1.00 89.86  ? 247 GLN B OE1 1 
ATOM   8100  N  NE2 . GLN B 1 247 ? 197.104 206.344 263.491 1.00 90.70  ? 247 GLN B NE2 1 
ATOM   8101  N  N   . ASN B 1 248 ? 197.994 208.080 257.551 1.00 80.57  ? 248 ASN B N   1 
ATOM   8102  C  CA  . ASN B 1 248 ? 198.626 209.284 257.032 1.00 75.57  ? 248 ASN B CA  1 
ATOM   8103  C  C   . ASN B 1 248 ? 199.484 208.915 255.829 1.00 68.30  ? 248 ASN B C   1 
ATOM   8104  O  O   . ASN B 1 248 ? 199.597 207.747 255.453 1.00 67.35  ? 248 ASN B O   1 
ATOM   8105  C  CB  . ASN B 1 248 ? 199.463 209.975 258.108 1.00 75.23  ? 248 ASN B CB  1 
ATOM   8106  C  CG  . ASN B 1 248 ? 198.616 210.709 259.123 1.00 81.29  ? 248 ASN B CG  1 
ATOM   8107  O  OD1 . ASN B 1 248 ? 197.633 211.359 258.772 1.00 82.57  ? 248 ASN B OD1 1 
ATOM   8108  N  ND2 . ASN B 1 248 ? 198.991 210.607 260.393 1.00 82.84  ? 248 ASN B ND2 1 
ATOM   8109  N  N   . LEU B 1 249 ? 200.083 209.932 255.222 1.00 61.60  ? 249 LEU B N   1 
ATOM   8110  C  CA  . LEU B 1 249 ? 201.040 209.751 254.144 1.00 61.57  ? 249 LEU B CA  1 
ATOM   8111  C  C   . LEU B 1 249 ? 202.246 210.631 254.426 1.00 58.52  ? 249 LEU B C   1 
ATOM   8112  O  O   . LEU B 1 249 ? 202.144 211.625 255.142 1.00 66.26  ? 249 LEU B O   1 
ATOM   8113  C  CB  . LEU B 1 249 ? 200.436 210.097 252.778 1.00 67.82  ? 249 LEU B CB  1 
ATOM   8114  C  CG  . LEU B 1 249 ? 199.187 209.324 252.351 1.00 79.04  ? 249 LEU B CG  1 
ATOM   8115  C  CD1 . LEU B 1 249 ? 197.935 210.156 252.577 1.00 84.87  ? 249 LEU B CD1 1 
ATOM   8116  C  CD2 . LEU B 1 249 ? 199.294 208.906 250.894 1.00 77.63  ? 249 LEU B CD2 1 
ATOM   8117  N  N   . VAL B 1 250 ? 203.393 210.259 253.873 1.00 46.13  ? 250 VAL B N   1 
ATOM   8118  C  CA  . VAL B 1 250 ? 204.639 210.967 254.119 1.00 40.10  ? 250 VAL B CA  1 
ATOM   8119  C  C   . VAL B 1 250 ? 205.310 211.242 252.792 1.00 41.63  ? 250 VAL B C   1 
ATOM   8120  O  O   . VAL B 1 250 ? 205.342 210.371 251.918 1.00 53.92  ? 250 VAL B O   1 
ATOM   8121  C  CB  . VAL B 1 250 ? 205.568 210.169 255.042 1.00 45.63  ? 250 VAL B CB  1 
ATOM   8122  C  CG1 . VAL B 1 250 ? 206.982 210.692 254.958 1.00 49.66  ? 250 VAL B CG1 1 
ATOM   8123  C  CG2 . VAL B 1 250 ? 205.088 210.297 256.428 1.00 49.62  ? 250 VAL B CG2 1 
ATOM   8124  N  N   . MET B 1 251 ? 205.852 212.443 252.637 1.00 40.28  ? 251 MET B N   1 
ATOM   8125  C  CA  . MET B 1 251 ? 206.366 212.860 251.351 1.00 45.62  ? 251 MET B CA  1 
ATOM   8126  C  C   . MET B 1 251 ? 207.750 213.461 251.530 1.00 46.79  ? 251 MET B C   1 
ATOM   8127  O  O   . MET B 1 251 ? 207.983 214.246 252.456 1.00 53.56  ? 251 MET B O   1 
ATOM   8128  C  CB  . MET B 1 251 ? 205.414 213.867 250.708 1.00 50.29  ? 251 MET B CB  1 
ATOM   8129  C  CG  . MET B 1 251 ? 204.488 213.215 249.704 1.00 62.54  ? 251 MET B CG  1 
ATOM   8130  S  SD  . MET B 1 251 ? 203.584 214.249 248.544 1.00 87.53  ? 251 MET B SD  1 
ATOM   8131  C  CE  . MET B 1 251 ? 204.917 215.088 247.731 1.00 69.71  ? 251 MET B CE  1 
ATOM   8132  N  N   . THR B 1 252 ? 208.656 213.100 250.628 1.00 45.19  ? 252 THR B N   1 
ATOM   8133  C  CA  . THR B 1 252 ? 210.013 213.613 250.592 1.00 46.90  ? 252 THR B CA  1 
ATOM   8134  C  C   . THR B 1 252 ? 210.185 214.495 249.365 1.00 53.03  ? 252 THR B C   1 
ATOM   8135  O  O   . THR B 1 252 ? 209.635 214.205 248.300 1.00 59.25  ? 252 THR B O   1 
ATOM   8136  C  CB  . THR B 1 252 ? 211.025 212.473 250.568 1.00 52.17  ? 252 THR B CB  1 
ATOM   8137  O  OG1 . THR B 1 252 ? 210.730 211.553 251.628 1.00 58.27  ? 252 THR B OG1 1 
ATOM   8138  C  CG2 . THR B 1 252 ? 212.431 213.005 250.759 1.00 50.72  ? 252 THR B CG2 1 
ATOM   8139  N  N   . PHE B 1 253 ? 210.953 215.568 249.515 1.00 51.62  ? 253 PHE B N   1 
ATOM   8140  C  CA  . PHE B 1 253 ? 210.976 216.673 248.566 1.00 51.28  ? 253 PHE B CA  1 
ATOM   8141  C  C   . PHE B 1 253 ? 212.396 217.013 248.154 1.00 50.40  ? 253 PHE B C   1 
ATOM   8142  O  O   . PHE B 1 253 ? 212.807 218.172 248.166 1.00 56.67  ? 253 PHE B O   1 
ATOM   8143  C  CB  . PHE B 1 253 ? 210.303 217.885 249.181 1.00 56.04  ? 253 PHE B CB  1 
ATOM   8144  C  CG  . PHE B 1 253 ? 208.848 217.974 248.898 1.00 58.68  ? 253 PHE B CG  1 
ATOM   8145  C  CD1 . PHE B 1 253 ? 208.336 217.503 247.711 1.00 61.19  ? 253 PHE B CD1 1 
ATOM   8146  C  CD2 . PHE B 1 253 ? 207.992 218.535 249.815 1.00 58.35  ? 253 PHE B CD2 1 
ATOM   8147  C  CE1 . PHE B 1 253 ? 207.002 217.599 247.443 1.00 64.07  ? 253 PHE B CE1 1 
ATOM   8148  C  CE2 . PHE B 1 253 ? 206.655 218.626 249.556 1.00 65.38  ? 253 PHE B CE2 1 
ATOM   8149  C  CZ  . PHE B 1 253 ? 206.156 218.158 248.368 1.00 69.92  ? 253 PHE B CZ  1 
ATOM   8150  N  N   . SER B 1 254 ? 213.178 216.005 247.794 1.00 49.46  ? 254 SER B N   1 
ATOM   8151  C  CA  . SER B 1 254 ? 214.576 216.241 247.467 1.00 56.07  ? 254 SER B CA  1 
ATOM   8152  C  C   . SER B 1 254 ? 214.698 217.173 246.269 1.00 69.03  ? 254 SER B C   1 
ATOM   8153  O  O   . SER B 1 254 ? 213.900 217.112 245.330 1.00 73.29  ? 254 SER B O   1 
ATOM   8154  C  CB  . SER B 1 254 ? 215.278 214.917 247.175 1.00 62.41  ? 254 SER B CB  1 
ATOM   8155  O  OG  . SER B 1 254 ? 216.645 214.973 247.541 1.00 68.09  ? 254 SER B OG  1 
ATOM   8156  N  N   . ASP B 1 255 ? 215.701 218.049 246.309 1.00 74.40  ? 255 ASP B N   1 
ATOM   8157  C  CA  . ASP B 1 255 ? 215.940 219.021 245.242 1.00 75.70  ? 255 ASP B CA  1 
ATOM   8158  C  C   . ASP B 1 255 ? 216.969 218.435 244.282 1.00 76.22  ? 255 ASP B C   1 
ATOM   8159  O  O   . ASP B 1 255 ? 218.169 218.425 244.567 1.00 76.30  ? 255 ASP B O   1 
ATOM   8160  C  CB  . ASP B 1 255 ? 216.411 220.348 245.823 1.00 78.82  ? 255 ASP B CB  1 
ATOM   8161  C  CG  . ASP B 1 255 ? 215.780 221.543 245.138 1.00 85.52  ? 255 ASP B CG  1 
ATOM   8162  O  OD1 . ASP B 1 255 ? 214.562 221.501 244.870 1.00 86.24  ? 255 ASP B OD1 1 
ATOM   8163  O  OD2 . ASP B 1 255 ? 216.503 222.525 244.869 1.00 87.08  ? 255 ASP B OD2 1 
ATOM   8164  N  N   . ILE B 1 256 ? 216.501 217.965 243.131 1.00 75.07  ? 256 ILE B N   1 
ATOM   8165  C  CA  . ILE B 1 256 ? 217.355 217.304 242.157 1.00 75.07  ? 256 ILE B CA  1 
ATOM   8166  C  C   . ILE B 1 256 ? 217.729 218.243 241.010 1.00 81.21  ? 256 ILE B C   1 
ATOM   8167  O  O   . ILE B 1 256 ? 218.117 217.782 239.940 1.00 82.90  ? 256 ILE B O   1 
ATOM   8168  C  CB  . ILE B 1 256 ? 216.706 216.021 241.625 1.00 73.98  ? 256 ILE B CB  1 
ATOM   8169  C  CG1 . ILE B 1 256 ? 215.336 216.335 241.029 1.00 74.33  ? 256 ILE B CG1 1 
ATOM   8170  C  CG2 . ILE B 1 256 ? 216.580 214.990 242.733 1.00 75.42  ? 256 ILE B CG2 1 
ATOM   8171  C  CD1 . ILE B 1 256 ? 215.137 215.763 239.648 1.00 78.39  ? 256 ILE B CD1 1 
ATOM   8172  N  N   . THR B 1 257 ? 217.617 219.557 241.219 1.00 82.97  ? 257 THR B N   1 
ATOM   8173  C  CA  . THR B 1 257 ? 217.941 220.515 240.169 1.00 78.81  ? 257 THR B CA  1 
ATOM   8174  C  C   . THR B 1 257 ? 219.394 220.429 239.740 1.00 76.33  ? 257 THR B C   1 
ATOM   8175  O  O   . THR B 1 257 ? 219.703 220.719 238.583 1.00 77.45  ? 257 THR B O   1 
ATOM   8176  C  CB  . THR B 1 257 ? 217.623 221.935 240.629 1.00 85.98  ? 257 THR B CB  1 
ATOM   8177  O  OG1 . THR B 1 257 ? 218.067 222.869 239.638 1.00 89.92  ? 257 THR B OG1 1 
ATOM   8178  C  CG2 . THR B 1 257 ? 218.307 222.237 241.954 1.00 86.76  ? 257 THR B CG2 1 
ATOM   8179  N  N   . GLU B 1 258 ? 220.294 220.057 240.643 1.00 77.05  ? 258 GLU B N   1 
ATOM   8180  C  CA  . GLU B 1 258 ? 221.659 219.770 240.234 1.00 81.31  ? 258 GLU B CA  1 
ATOM   8181  C  C   . GLU B 1 258 ? 221.793 218.367 239.672 1.00 84.67  ? 258 GLU B C   1 
ATOM   8182  O  O   . GLU B 1 258 ? 222.534 218.155 238.707 1.00 86.19  ? 258 GLU B O   1 
ATOM   8183  C  CB  . GLU B 1 258 ? 222.620 219.954 241.406 1.00 85.96  ? 258 GLU B CB  1 
ATOM   8184  C  CG  . GLU B 1 258 ? 223.314 221.298 241.412 1.00 95.49  ? 258 GLU B CG  1 
ATOM   8185  C  CD  . GLU B 1 258 ? 224.294 221.442 242.556 1.00 106.31 ? 258 GLU B CD  1 
ATOM   8186  O  OE1 . GLU B 1 258 ? 224.667 220.410 243.151 1.00 105.67 ? 258 GLU B OE1 1 
ATOM   8187  O  OE2 . GLU B 1 258 ? 224.696 222.586 242.855 1.00 112.25 ? 258 GLU B OE2 1 
ATOM   8188  N  N   . GLU B 1 259 ? 221.086 217.400 240.255 1.00 84.70  ? 259 GLU B N   1 
ATOM   8189  C  CA  . GLU B 1 259 ? 221.189 216.035 239.762 1.00 83.93  ? 259 GLU B CA  1 
ATOM   8190  C  C   . GLU B 1 259 ? 220.559 215.891 238.385 1.00 80.16  ? 259 GLU B C   1 
ATOM   8191  O  O   . GLU B 1 259 ? 221.123 215.220 237.520 1.00 76.84  ? 259 GLU B O   1 
ATOM   8192  C  CB  . GLU B 1 259 ? 220.565 215.061 240.755 1.00 83.21  ? 259 GLU B CB  1 
ATOM   8193  C  CG  . GLU B 1 259 ? 221.136 213.658 240.651 1.00 87.46  ? 259 GLU B CG  1 
ATOM   8194  C  CD  . GLU B 1 259 ? 222.569 213.565 241.142 1.00 91.06  ? 259 GLU B CD  1 
ATOM   8195  O  OE1 . GLU B 1 259 ? 223.038 214.504 241.818 1.00 92.11  ? 259 GLU B OE1 1 
ATOM   8196  O  OE2 . GLU B 1 259 ? 223.230 212.548 240.850 1.00 92.77  ? 259 GLU B OE2 1 
ATOM   8197  N  N   . ARG B 1 260 ? 219.410 216.530 238.147 1.00 78.80  ? 260 ARG B N   1 
ATOM   8198  C  CA  . ARG B 1 260 ? 218.804 216.434 236.823 1.00 73.03  ? 260 ARG B CA  1 
ATOM   8199  C  C   . ARG B 1 260 ? 219.738 216.950 235.751 1.00 71.39  ? 260 ARG B C   1 
ATOM   8200  O  O   . ARG B 1 260 ? 219.707 216.471 234.617 1.00 74.50  ? 260 ARG B O   1 
ATOM   8201  C  CB  . ARG B 1 260 ? 217.490 217.198 236.730 1.00 73.10  ? 260 ARG B CB  1 
ATOM   8202  C  CG  . ARG B 1 260 ? 216.532 216.503 235.801 1.00 74.05  ? 260 ARG B CG  1 
ATOM   8203  C  CD  . ARG B 1 260 ? 215.167 217.099 235.835 1.00 80.44  ? 260 ARG B CD  1 
ATOM   8204  N  NE  . ARG B 1 260 ? 215.132 218.293 235.004 1.00 85.26  ? 260 ARG B NE  1 
ATOM   8205  C  CZ  . ARG B 1 260 ? 215.003 218.276 233.685 1.00 90.68  ? 260 ARG B CZ  1 
ATOM   8206  N  NH1 . ARG B 1 260 ? 214.862 217.141 233.019 1.00 91.69  ? 260 ARG B NH1 1 
ATOM   8207  N  NH2 . ARG B 1 260 ? 215.017 219.425 233.017 1.00 92.41  ? 260 ARG B NH2 1 
ATOM   8208  N  N   . GLN B 1 261 ? 220.557 217.943 236.077 1.00 73.60  ? 261 GLN B N   1 
ATOM   8209  C  CA  . GLN B 1 261 ? 221.524 218.400 235.096 1.00 78.96  ? 261 GLN B CA  1 
ATOM   8210  C  C   . GLN B 1 261 ? 222.489 217.283 234.756 1.00 76.24  ? 261 GLN B C   1 
ATOM   8211  O  O   . GLN B 1 261 ? 222.836 217.085 233.589 1.00 82.39  ? 261 GLN B O   1 
ATOM   8212  C  CB  . GLN B 1 261 ? 222.266 219.633 235.606 1.00 85.07  ? 261 GLN B CB  1 
ATOM   8213  C  CG  . GLN B 1 261 ? 221.396 220.873 235.673 1.00 88.32  ? 261 GLN B CG  1 
ATOM   8214  C  CD  . GLN B 1 261 ? 222.204 222.134 235.842 1.00 93.69  ? 261 GLN B CD  1 
ATOM   8215  O  OE1 . GLN B 1 261 ? 223.398 222.084 236.134 1.00 98.02  ? 261 GLN B OE1 1 
ATOM   8216  N  NE2 . GLN B 1 261 ? 221.558 223.278 235.659 1.00 91.80  ? 261 GLN B NE2 1 
ATOM   8217  N  N   . ILE B 1 262 ? 222.896 216.514 235.761 1.00 69.55  ? 262 ILE B N   1 
ATOM   8218  C  CA  . ILE B 1 262 ? 223.788 215.390 235.521 1.00 69.83  ? 262 ILE B CA  1 
ATOM   8219  C  C   . ILE B 1 262 ? 223.087 214.299 234.717 1.00 76.22  ? 262 ILE B C   1 
ATOM   8220  O  O   . ILE B 1 262 ? 223.676 213.695 233.813 1.00 77.75  ? 262 ILE B O   1 
ATOM   8221  C  CB  . ILE B 1 262 ? 224.332 214.873 236.858 1.00 71.01  ? 262 ILE B CB  1 
ATOM   8222  C  CG1 . ILE B 1 262 ? 225.547 215.698 237.249 1.00 73.68  ? 262 ILE B CG1 1 
ATOM   8223  C  CG2 . ILE B 1 262 ? 224.685 213.407 236.766 1.00 74.42  ? 262 ILE B CG2 1 
ATOM   8224  C  CD1 . ILE B 1 262 ? 226.708 215.467 236.331 1.00 74.98  ? 262 ILE B CD1 1 
ATOM   8225  N  N   . ARG B 1 263 ? 221.817 214.033 235.021 1.00 77.02  ? 263 ARG B N   1 
ATOM   8226  C  CA  . ARG B 1 263 ? 221.103 212.981 234.304 1.00 74.75  ? 263 ARG B CA  1 
ATOM   8227  C  C   . ARG B 1 263 ? 220.850 213.376 232.854 1.00 75.75  ? 263 ARG B C   1 
ATOM   8228  O  O   . ARG B 1 263 ? 220.926 212.535 231.953 1.00 75.68  ? 263 ARG B O   1 
ATOM   8229  C  CB  . ARG B 1 263 ? 219.787 212.645 235.004 1.00 72.92  ? 263 ARG B CB  1 
ATOM   8230  C  CG  . ARG B 1 263 ? 219.829 212.631 236.527 1.00 77.37  ? 263 ARG B CG  1 
ATOM   8231  C  CD  . ARG B 1 263 ? 221.013 211.857 237.110 1.00 80.95  ? 263 ARG B CD  1 
ATOM   8232  N  NE  . ARG B 1 263 ? 221.099 210.473 236.659 1.00 81.34  ? 263 ARG B NE  1 
ATOM   8233  C  CZ  . ARG B 1 263 ? 222.001 209.605 237.098 1.00 80.80  ? 263 ARG B CZ  1 
ATOM   8234  N  NH1 . ARG B 1 263 ? 222.913 209.949 237.992 1.00 80.06  ? 263 ARG B NH1 1 
ATOM   8235  N  NH2 . ARG B 1 263 ? 221.987 208.360 236.630 1.00 79.92  ? 263 ARG B NH2 1 
ATOM   8236  N  N   . GLN B 1 264 ? 220.542 214.649 232.610 1.00 76.34  ? 264 GLN B N   1 
ATOM   8237  C  CA  . GLN B 1 264 ? 220.387 215.128 231.244 1.00 69.97  ? 264 GLN B CA  1 
ATOM   8238  C  C   . GLN B 1 264 ? 221.723 215.144 230.521 1.00 67.83  ? 264 GLN B C   1 
ATOM   8239  O  O   . GLN B 1 264 ? 221.786 214.882 229.316 1.00 75.35  ? 264 GLN B O   1 
ATOM   8240  C  CB  . GLN B 1 264 ? 219.759 216.516 231.247 1.00 72.07  ? 264 GLN B CB  1 
ATOM   8241  C  CG  . GLN B 1 264 ? 218.510 216.622 230.409 1.00 78.51  ? 264 GLN B CG  1 
ATOM   8242  C  CD  . GLN B 1 264 ? 217.930 218.017 230.413 1.00 86.84  ? 264 GLN B CD  1 
ATOM   8243  O  OE1 . GLN B 1 264 ? 218.663 219.006 230.425 1.00 87.03  ? 264 GLN B OE1 1 
ATOM   8244  N  NE2 . GLN B 1 264 ? 216.606 218.107 230.409 1.00 89.48  ? 264 GLN B NE2 1 
ATOM   8245  N  N   . LEU B 1 265 ? 222.801 215.448 231.241 1.00 63.31  ? 265 LEU B N   1 
ATOM   8246  C  CA  . LEU B 1 265 ? 224.131 215.270 230.686 1.00 65.14  ? 265 LEU B CA  1 
ATOM   8247  C  C   . LEU B 1 265 ? 224.308 213.840 230.211 1.00 73.13  ? 265 LEU B C   1 
ATOM   8248  O  O   . LEU B 1 265 ? 224.793 213.595 229.101 1.00 83.46  ? 265 LEU B O   1 
ATOM   8249  C  CB  . LEU B 1 265 ? 225.183 215.641 231.736 1.00 68.04  ? 265 LEU B CB  1 
ATOM   8250  C  CG  . LEU B 1 265 ? 226.658 215.332 231.457 1.00 69.74  ? 265 LEU B CG  1 
ATOM   8251  C  CD1 . LEU B 1 265 ? 227.556 216.334 232.131 1.00 74.11  ? 265 LEU B CD1 1 
ATOM   8252  C  CD2 . LEU B 1 265 ? 227.042 213.941 231.925 1.00 76.15  ? 265 LEU B CD2 1 
ATOM   8253  N  N   . GLU B 1 266 ? 223.898 212.881 231.038 1.00 71.79  ? 266 GLU B N   1 
ATOM   8254  C  CA  . GLU B 1 266 ? 224.035 211.477 230.673 1.00 73.36  ? 266 GLU B CA  1 
ATOM   8255  C  C   . GLU B 1 266 ? 223.196 211.133 229.453 1.00 72.59  ? 266 GLU B C   1 
ATOM   8256  O  O   . GLU B 1 266 ? 223.662 210.436 228.546 1.00 71.52  ? 266 GLU B O   1 
ATOM   8257  C  CB  . GLU B 1 266 ? 223.650 210.592 231.855 1.00 76.35  ? 266 GLU B CB  1 
ATOM   8258  C  CG  . GLU B 1 266 ? 224.804 210.267 232.775 1.00 82.78  ? 266 GLU B CG  1 
ATOM   8259  C  CD  . GLU B 1 266 ? 226.059 209.862 232.027 1.00 90.36  ? 266 GLU B CD  1 
ATOM   8260  O  OE1 . GLU B 1 266 ? 225.957 209.278 230.926 1.00 91.01  ? 266 GLU B OE1 1 
ATOM   8261  O  OE2 . GLU B 1 266 ? 227.160 210.136 232.540 1.00 93.23  ? 266 GLU B OE2 1 
ATOM   8262  N  N   . GLY B 1 267 ? 221.955 211.611 229.417 1.00 73.05  ? 267 GLY B N   1 
ATOM   8263  C  CA  . GLY B 1 267 ? 221.086 211.297 228.295 1.00 69.53  ? 267 GLY B CA  1 
ATOM   8264  C  C   . GLY B 1 267 ? 221.609 211.858 226.990 1.00 69.53  ? 267 GLY B C   1 
ATOM   8265  O  O   . GLY B 1 267 ? 221.650 211.166 225.968 1.00 76.91  ? 267 GLY B O   1 
ATOM   8266  N  N   . ASN B 1 268 ? 222.026 213.123 227.010 1.00 65.89  ? 268 ASN B N   1 
ATOM   8267  C  CA  . ASN B 1 268 ? 222.547 213.748 225.805 1.00 66.54  ? 268 ASN B CA  1 
ATOM   8268  C  C   . ASN B 1 268 ? 223.847 213.096 225.361 1.00 69.57  ? 268 ASN B C   1 
ATOM   8269  O  O   . ASN B 1 268 ? 224.037 212.827 224.168 1.00 75.42  ? 268 ASN B O   1 
ATOM   8270  C  CB  . ASN B 1 268 ? 222.731 215.240 226.042 1.00 69.99  ? 268 ASN B CB  1 
ATOM   8271  C  CG  . ASN B 1 268 ? 221.420 215.941 226.313 1.00 75.45  ? 268 ASN B CG  1 
ATOM   8272  O  OD1 . ASN B 1 268 ? 220.379 215.302 226.417 1.00 72.65  ? 268 ASN B OD1 1 
ATOM   8273  N  ND2 . ASN B 1 268 ? 221.462 217.262 226.419 1.00 78.93  ? 268 ASN B ND2 1 
ATOM   8274  N  N   . ILE B 1 269 ? 224.742 212.788 226.299 1.00 67.17  ? 269 ILE B N   1 
ATOM   8275  C  CA  . ILE B 1 269 ? 225.983 212.155 225.881 1.00 70.06  ? 269 ILE B CA  1 
ATOM   8276  C  C   . ILE B 1 269 ? 225.733 210.757 225.334 1.00 79.88  ? 269 ILE B C   1 
ATOM   8277  O  O   . ILE B 1 269 ? 226.411 210.334 224.395 1.00 83.88  ? 269 ILE B O   1 
ATOM   8278  C  CB  . ILE B 1 269 ? 227.012 212.150 227.021 1.00 72.68  ? 269 ILE B CB  1 
ATOM   8279  C  CG1 . ILE B 1 269 ? 228.392 211.807 226.475 1.00 74.35  ? 269 ILE B CG1 1 
ATOM   8280  C  CG2 . ILE B 1 269 ? 226.620 211.200 228.123 1.00 79.71  ? 269 ILE B CG2 1 
ATOM   8281  C  CD1 . ILE B 1 269 ? 229.502 212.087 227.450 1.00 82.29  ? 269 ILE B CD1 1 
ATOM   8282  N  N   . LEU B 1 270 ? 224.770 210.012 225.888 1.00 81.36  ? 270 LEU B N   1 
ATOM   8283  C  CA  . LEU B 1 270 ? 224.494 208.682 225.349 1.00 77.21  ? 270 LEU B CA  1 
ATOM   8284  C  C   . LEU B 1 270 ? 223.881 208.770 223.960 1.00 73.89  ? 270 LEU B C   1 
ATOM   8285  O  O   . LEU B 1 270 ? 224.254 208.006 223.059 1.00 75.24  ? 270 LEU B O   1 
ATOM   8286  C  CB  . LEU B 1 270 ? 223.584 207.902 226.291 1.00 75.42  ? 270 LEU B CB  1 
ATOM   8287  C  CG  . LEU B 1 270 ? 224.286 206.808 227.098 1.00 78.10  ? 270 LEU B CG  1 
ATOM   8288  C  CD1 . LEU B 1 270 ? 224.896 205.763 226.188 1.00 70.75  ? 270 LEU B CD1 1 
ATOM   8289  C  CD2 . LEU B 1 270 ? 225.340 207.402 228.010 1.00 78.46  ? 270 LEU B CD2 1 
ATOM   8290  N  N   . ALA B 1 271 ? 222.937 209.691 223.766 1.00 74.66  ? 271 ALA B N   1 
ATOM   8291  C  CA  . ALA B 1 271 ? 222.436 209.934 222.422 1.00 75.43  ? 271 ALA B CA  1 
ATOM   8292  C  C   . ALA B 1 271 ? 223.561 210.329 221.486 1.00 82.22  ? 271 ALA B C   1 
ATOM   8293  O  O   . ALA B 1 271 ? 223.437 210.150 220.270 1.00 87.36  ? 271 ALA B O   1 
ATOM   8294  C  CB  . ALA B 1 271 ? 221.359 211.016 222.437 1.00 71.70  ? 271 ALA B CB  1 
ATOM   8295  N  N   . ALA B 1 272 ? 224.652 210.872 222.027 1.00 84.01  ? 272 ALA B N   1 
ATOM   8296  C  CA  . ALA B 1 272 ? 225.843 211.092 221.214 1.00 87.40  ? 272 ALA B CA  1 
ATOM   8297  C  C   . ALA B 1 272 ? 226.516 209.773 220.851 1.00 86.00  ? 272 ALA B C   1 
ATOM   8298  O  O   . ALA B 1 272 ? 226.689 209.464 219.667 1.00 90.22  ? 272 ALA B O   1 
ATOM   8299  C  CB  . ALA B 1 272 ? 226.820 212.018 221.938 1.00 86.55  ? 272 ALA B CB  1 
ATOM   8300  N  N   . MET B 1 273 ? 226.911 208.972 221.855 1.00 80.75  ? 273 MET B N   1 
ATOM   8301  C  CA  . MET B 1 273 ? 227.718 207.846 221.323 1.00 87.73  ? 273 MET B CA  1 
ATOM   8302  C  C   . MET B 1 273 ? 226.863 206.773 220.677 1.00 91.54  ? 273 MET B C   1 
ATOM   8303  O  O   . MET B 1 273 ? 227.450 205.768 220.242 1.00 91.04  ? 273 MET B O   1 
ATOM   8304  C  CB  . MET B 1 273 ? 228.621 207.092 222.314 1.00 89.44  ? 273 MET B CB  1 
ATOM   8305  C  CG  . MET B 1 273 ? 228.160 206.770 223.730 1.00 90.98  ? 273 MET B CG  1 
ATOM   8306  S  SD  . MET B 1 273 ? 227.900 208.076 224.904 1.00 98.96  ? 273 MET B SD  1 
ATOM   8307  C  CE  . MET B 1 273 ? 229.533 208.792 224.929 1.00 92.30  ? 273 MET B CE  1 
ATOM   8308  N  N   . CYS B 1 274 ? 225.540 206.930 220.609 1.00 92.94  ? 274 CYS B N   1 
ATOM   8309  C  CA  . CYS B 1 274 ? 224.711 205.886 220.014 1.00 94.47  ? 274 CYS B CA  1 
ATOM   8310  C  C   . CYS B 1 274 ? 225.148 205.557 218.590 1.00 96.67  ? 274 CYS B C   1 
ATOM   8311  O  O   . CYS B 1 274 ? 224.971 204.425 218.129 1.00 97.20  ? 274 CYS B O   1 
ATOM   8312  C  CB  . CYS B 1 274 ? 223.240 206.307 220.040 1.00 96.19  ? 274 CYS B CB  1 
ATOM   8313  S  SG  . CYS B 1 274 ? 222.736 207.392 218.684 1.00 105.74 ? 274 CYS B SG  1 
ATOM   8314  N  N   . SER B 1 275 ? 225.723 206.526 217.877 1.00 97.17  ? 275 SER B N   1 
ATOM   8315  C  CA  . SER B 1 275 ? 226.108 206.323 216.484 1.00 98.69  ? 275 SER B CA  1 
ATOM   8316  C  C   . SER B 1 275 ? 227.606 206.443 216.245 1.00 100.70 ? 275 SER B C   1 
ATOM   8317  O  O   . SER B 1 275 ? 228.034 206.430 215.086 1.00 104.31 ? 275 SER B O   1 
ATOM   8318  C  CB  . SER B 1 275 ? 225.370 207.309 215.579 1.00 95.41  ? 275 SER B CB  1 
ATOM   8319  O  OG  . SER B 1 275 ? 226.193 208.421 215.278 1.00 94.50  ? 275 SER B OG  1 
ATOM   8320  N  N   . SER B 1 276 ? 228.406 206.557 217.296 1.00 99.69  ? 276 SER B N   1 
ATOM   8321  C  CA  . SER B 1 276 ? 229.857 206.688 217.196 1.00 101.15 ? 276 SER B CA  1 
ATOM   8322  C  C   . SER B 1 276 ? 230.277 207.792 216.230 1.00 101.44 ? 276 SER B C   1 
ATOM   8323  O  O   . SER B 1 276 ? 230.812 207.497 215.156 1.00 99.84  ? 276 SER B O   1 
ATOM   8324  C  CB  . SER B 1 276 ? 230.482 205.363 216.760 1.00 102.97 ? 276 SER B CB  1 
ATOM   8325  O  OG  . SER B 1 276 ? 230.331 205.172 215.364 1.00 105.42 ? 276 SER B OG  1 
ATOM   8326  N  N   . PRO B 1 277 ? 230.055 209.060 216.562 1.00 102.84 ? 277 PRO B N   1 
ATOM   8327  C  CA  . PRO B 1 277 ? 230.605 210.145 215.750 1.00 105.10 ? 277 PRO B CA  1 
ATOM   8328  C  C   . PRO B 1 277 ? 232.120 210.165 215.841 1.00 108.68 ? 277 PRO B C   1 
ATOM   8329  O  O   . PRO B 1 277 ? 232.706 209.418 216.638 1.00 107.54 ? 277 PRO B O   1 
ATOM   8330  C  CB  . PRO B 1 277 ? 229.986 211.401 216.383 1.00 105.28 ? 277 PRO B CB  1 
ATOM   8331  C  CG  . PRO B 1 277 ? 228.756 210.925 217.033 1.00 101.10 ? 277 PRO B CG  1 
ATOM   8332  C  CD  . PRO B 1 277 ? 229.086 209.562 217.550 1.00 101.37 ? 277 PRO B CD  1 
ATOM   8333  N  N   . PRO B 1 278 ? 232.793 210.996 215.043 1.00 113.07 ? 278 PRO B N   1 
ATOM   8334  C  CA  . PRO B 1 278 ? 234.261 211.038 215.084 1.00 111.94 ? 278 PRO B CA  1 
ATOM   8335  C  C   . PRO B 1 278 ? 234.792 211.459 216.447 1.00 112.19 ? 278 PRO B C   1 
ATOM   8336  O  O   . PRO B 1 278 ? 234.060 211.883 217.344 1.00 113.02 ? 278 PRO B O   1 
ATOM   8337  C  CB  . PRO B 1 278 ? 234.616 212.066 214.006 1.00 111.90 ? 278 PRO B CB  1 
ATOM   8338  C  CG  . PRO B 1 278 ? 233.475 212.021 213.065 1.00 112.03 ? 278 PRO B CG  1 
ATOM   8339  C  CD  . PRO B 1 278 ? 232.261 211.768 213.906 1.00 113.33 ? 278 PRO B CD  1 
ATOM   8340  N  N   . PHE B 1 279 ? 236.113 211.330 216.589 1.00 110.69 ? 279 PHE B N   1 
ATOM   8341  C  CA  . PHE B 1 279 ? 236.764 211.562 217.876 1.00 116.33 ? 279 PHE B CA  1 
ATOM   8342  C  C   . PHE B 1 279 ? 236.621 213.013 218.319 1.00 116.37 ? 279 PHE B C   1 
ATOM   8343  O  O   . PHE B 1 279 ? 236.181 213.296 219.442 1.00 116.53 ? 279 PHE B O   1 
ATOM   8344  C  CB  . PHE B 1 279 ? 238.235 211.161 217.770 1.00 122.41 ? 279 PHE B CB  1 
ATOM   8345  C  CG  . PHE B 1 279 ? 238.951 211.101 219.085 1.00 129.75 ? 279 PHE B CG  1 
ATOM   8346  C  CD1 . PHE B 1 279 ? 238.427 210.377 220.142 1.00 128.79 ? 279 PHE B CD1 1 
ATOM   8347  C  CD2 . PHE B 1 279 ? 240.169 211.739 219.254 1.00 134.09 ? 279 PHE B CD2 1 
ATOM   8348  C  CE1 . PHE B 1 279 ? 239.092 210.311 221.351 1.00 130.41 ? 279 PHE B CE1 1 
ATOM   8349  C  CE2 . PHE B 1 279 ? 240.840 211.674 220.460 1.00 135.39 ? 279 PHE B CE2 1 
ATOM   8350  C  CZ  . PHE B 1 279 ? 240.300 210.960 221.510 1.00 134.11 ? 279 PHE B CZ  1 
ATOM   8351  N  N   . HIS B 1 280 ? 236.986 213.950 217.441 1.00 117.42 ? 280 HIS B N   1 
ATOM   8352  C  CA  . HIS B 1 280 ? 236.862 215.366 217.772 1.00 120.43 ? 280 HIS B CA  1 
ATOM   8353  C  C   . HIS B 1 280 ? 235.407 215.739 218.011 1.00 115.80 ? 280 HIS B C   1 
ATOM   8354  O  O   . HIS B 1 280 ? 235.092 216.517 218.920 1.00 115.89 ? 280 HIS B O   1 
ATOM   8355  C  CB  . HIS B 1 280 ? 237.462 216.215 216.651 1.00 124.59 ? 280 HIS B CB  1 
ATOM   8356  C  CG  . HIS B 1 280 ? 237.396 217.689 216.903 1.00 129.21 ? 280 HIS B CG  1 
ATOM   8357  N  ND1 . HIS B 1 280 ? 238.295 218.344 217.718 1.00 130.35 ? 280 HIS B ND1 1 
ATOM   8358  C  CD2 . HIS B 1 280 ? 236.548 218.637 216.440 1.00 127.95 ? 280 HIS B CD2 1 
ATOM   8359  C  CE1 . HIS B 1 280 ? 237.999 219.631 217.750 1.00 129.38 ? 280 HIS B CE1 1 
ATOM   8360  N  NE2 . HIS B 1 280 ? 236.944 219.836 216.983 1.00 130.49 ? 280 HIS B NE2 1 
ATOM   8361  N  N   . GLU B 1 281 ? 234.502 215.177 217.212 1.00 110.18 ? 281 GLU B N   1 
ATOM   8362  C  CA  . GLU B 1 281 ? 233.086 215.426 217.427 1.00 107.35 ? 281 GLU B CA  1 
ATOM   8363  C  C   . GLU B 1 281 ? 232.649 214.923 218.796 1.00 106.90 ? 281 GLU B C   1 
ATOM   8364  O  O   . GLU B 1 281 ? 231.899 215.605 219.503 1.00 106.40 ? 281 GLU B O   1 
ATOM   8365  C  CB  . GLU B 1 281 ? 232.269 214.763 216.320 1.00 108.13 ? 281 GLU B CB  1 
ATOM   8366  C  CG  . GLU B 1 281 ? 230.801 215.168 216.261 1.00 109.70 ? 281 GLU B CG  1 
ATOM   8367  C  CD  . GLU B 1 281 ? 230.549 216.627 216.613 1.00 112.63 ? 281 GLU B CD  1 
ATOM   8368  O  OE1 . GLU B 1 281 ? 231.341 217.504 216.203 1.00 113.27 ? 281 GLU B OE1 1 
ATOM   8369  O  OE2 . GLU B 1 281 ? 229.543 216.897 217.300 1.00 111.52 ? 281 GLU B OE2 1 
ATOM   8370  N  N   . MET B 1 282 ? 233.115 213.734 219.187 1.00 108.83 ? 282 MET B N   1 
ATOM   8371  C  CA  . MET B 1 282 ? 232.766 213.195 220.498 1.00 111.23 ? 282 MET B CA  1 
ATOM   8372  C  C   . MET B 1 282 ? 233.247 214.115 221.609 1.00 108.11 ? 282 MET B C   1 
ATOM   8373  O  O   . MET B 1 282 ? 232.512 214.387 222.575 1.00 104.50 ? 282 MET B O   1 
ATOM   8374  C  CB  . MET B 1 282 ? 233.354 211.794 220.664 1.00 113.56 ? 282 MET B CB  1 
ATOM   8375  C  CG  . MET B 1 282 ? 233.287 211.270 222.084 1.00 112.48 ? 282 MET B CG  1 
ATOM   8376  S  SD  . MET B 1 282 ? 231.728 210.441 222.431 1.00 109.72 ? 282 MET B SD  1 
ATOM   8377  C  CE  . MET B 1 282 ? 230.897 211.704 223.392 1.00 100.25 ? 282 MET B CE  1 
ATOM   8378  N  N   . GLY B 1 283 ? 234.474 214.615 221.481 1.00 109.01 ? 283 GLY B N   1 
ATOM   8379  C  CA  . GLY B 1 283 ? 234.929 215.630 222.407 1.00 103.38 ? 283 GLY B CA  1 
ATOM   8380  C  C   . GLY B 1 283 ? 233.998 216.823 222.423 1.00 95.33  ? 283 GLY B C   1 
ATOM   8381  O  O   . GLY B 1 283 ? 233.750 217.411 223.474 1.00 96.62  ? 283 GLY B O   1 
ATOM   8382  N  N   . GLU B 1 284 ? 233.455 217.181 221.261 1.00 97.35  ? 284 GLU B N   1 
ATOM   8383  C  CA  . GLU B 1 284 ? 232.555 218.327 221.202 1.00 97.35  ? 284 GLU B CA  1 
ATOM   8384  C  C   . GLU B 1 284 ? 231.283 218.085 222.007 1.00 93.35  ? 284 GLU B C   1 
ATOM   8385  O  O   . GLU B 1 284 ? 230.836 218.972 222.742 1.00 94.29  ? 284 GLU B O   1 
ATOM   8386  C  CB  . GLU B 1 284 ? 232.202 218.663 219.756 1.00 103.74 ? 284 GLU B CB  1 
ATOM   8387  C  CG  . GLU B 1 284 ? 231.989 220.145 219.517 1.00 103.99 ? 284 GLU B CG  1 
ATOM   8388  C  CD  . GLU B 1 284 ? 230.912 220.428 218.492 1.00 106.67 ? 284 GLU B CD  1 
ATOM   8389  O  OE1 . GLU B 1 284 ? 230.291 219.469 217.991 1.00 104.13 ? 284 GLU B OE1 1 
ATOM   8390  O  OE2 . GLU B 1 284 ? 230.695 221.616 218.177 1.00 109.55 ? 284 GLU B OE2 1 
ATOM   8391  N  N   . ILE B 1 285 ? 230.664 216.906 221.867 1.00 93.03  ? 285 ILE B N   1 
ATOM   8392  C  CA  . ILE B 1 285 ? 229.477 216.666 222.693 1.00 91.62  ? 285 ILE B CA  1 
ATOM   8393  C  C   . ILE B 1 285 ? 229.837 216.704 224.170 1.00 93.06  ? 285 ILE B C   1 
ATOM   8394  O  O   . ILE B 1 285 ? 229.119 217.317 224.974 1.00 92.47  ? 285 ILE B O   1 
ATOM   8395  C  CB  . ILE B 1 285 ? 228.695 215.374 222.355 1.00 90.80  ? 285 ILE B CB  1 
ATOM   8396  C  CG1 . ILE B 1 285 ? 228.558 215.049 220.866 1.00 94.05  ? 285 ILE B CG1 1 
ATOM   8397  C  CG2 . ILE B 1 285 ? 227.343 215.362 223.055 1.00 89.31  ? 285 ILE B CG2 1 
ATOM   8398  C  CD1 . ILE B 1 285 ? 229.576 214.203 220.311 1.00 96.21  ? 285 ILE B CD1 1 
ATOM   8399  N  N   . ILE B 1 286 ? 230.955 216.078 224.557 1.00 92.96  ? 286 ILE B N   1 
ATOM   8400  C  CA  . ILE B 1 286 ? 231.342 216.129 225.967 1.00 85.32  ? 286 ILE B CA  1 
ATOM   8401  C  C   . ILE B 1 286 ? 231.449 217.576 226.426 1.00 85.08  ? 286 ILE B C   1 
ATOM   8402  O  O   . ILE B 1 286 ? 230.886 217.963 227.456 1.00 83.00  ? 286 ILE B O   1 
ATOM   8403  C  CB  . ILE B 1 286 ? 232.657 215.369 226.203 1.00 90.67  ? 286 ILE B CB  1 
ATOM   8404  C  CG1 . ILE B 1 286 ? 232.396 213.870 226.302 1.00 93.01  ? 286 ILE B CG1 1 
ATOM   8405  C  CG2 . ILE B 1 286 ? 233.334 215.858 227.468 1.00 91.61  ? 286 ILE B CG2 1 
ATOM   8406  C  CD1 . ILE B 1 286 ? 233.642 213.027 226.244 1.00 101.00 ? 286 ILE B CD1 1 
ATOM   8407  N  N   . CYS B 1 287 ? 232.141 218.404 225.641 1.00 92.10  ? 287 CYS B N   1 
ATOM   8408  C  CA  . CYS B 1 287 ? 232.438 219.768 226.061 1.00 88.07  ? 287 CYS B CA  1 
ATOM   8409  C  C   . CYS B 1 287 ? 231.180 220.610 226.180 1.00 83.30  ? 287 CYS B C   1 
ATOM   8410  O  O   . CYS B 1 287 ? 231.001 221.329 227.168 1.00 89.06  ? 287 CYS B O   1 
ATOM   8411  C  CB  . CYS B 1 287 ? 233.417 220.420 225.089 1.00 91.46  ? 287 CYS B CB  1 
ATOM   8412  S  SG  . CYS B 1 287 ? 235.045 219.655 225.053 1.00 100.76 ? 287 CYS B SG  1 
ATOM   8413  N  N   . ARG B 1 288 ? 230.303 220.567 225.175 1.00 82.09  ? 288 ARG B N   1 
ATOM   8414  C  CA  . ARG B 1 288 ? 229.142 221.439 225.288 1.00 81.85  ? 288 ARG B CA  1 
ATOM   8415  C  C   . ARG B 1 288 ? 228.161 220.920 226.324 1.00 86.15  ? 288 ARG B C   1 
ATOM   8416  O  O   . ARG B 1 288 ? 227.434 221.714 226.926 1.00 91.33  ? 288 ARG B O   1 
ATOM   8417  C  CB  . ARG B 1 288 ? 228.425 221.653 223.955 1.00 85.34  ? 288 ARG B CB  1 
ATOM   8418  C  CG  . ARG B 1 288 ? 229.244 221.498 222.703 1.00 92.28  ? 288 ARG B CG  1 
ATOM   8419  C  CD  . ARG B 1 288 ? 228.343 220.982 221.593 1.00 97.16  ? 288 ARG B CD  1 
ATOM   8420  N  NE  . ARG B 1 288 ? 227.889 219.612 221.772 1.00 97.45  ? 288 ARG B NE  1 
ATOM   8421  C  CZ  . ARG B 1 288 ? 226.867 219.089 221.106 1.00 96.56  ? 288 ARG B CZ  1 
ATOM   8422  N  NH1 . ARG B 1 288 ? 226.158 219.809 220.252 1.00 98.65  ? 288 ARG B NH1 1 
ATOM   8423  N  NH2 . ARG B 1 288 ? 226.532 217.820 221.316 1.00 92.63  ? 288 ARG B NH2 1 
ATOM   8424  N  N   . ASN B 1 289 ? 228.139 219.608 226.575 1.00 85.52  ? 289 ASN B N   1 
ATOM   8425  C  CA  . ASN B 1 289 ? 227.333 219.112 227.684 1.00 86.97  ? 289 ASN B CA  1 
ATOM   8426  C  C   . ASN B 1 289 ? 227.867 219.612 229.018 1.00 92.54  ? 289 ASN B C   1 
ATOM   8427  O  O   . ASN B 1 289 ? 227.095 220.037 229.886 1.00 93.96  ? 289 ASN B O   1 
ATOM   8428  C  CB  . ASN B 1 289 ? 227.295 217.590 227.663 1.00 83.25  ? 289 ASN B CB  1 
ATOM   8429  C  CG  . ASN B 1 289 ? 226.353 217.058 226.619 1.00 87.79  ? 289 ASN B CG  1 
ATOM   8430  O  OD1 . ASN B 1 289 ? 226.612 216.029 226.003 1.00 90.17  ? 289 ASN B OD1 1 
ATOM   8431  N  ND2 . ASN B 1 289 ? 225.253 217.767 226.401 1.00 88.49  ? 289 ASN B ND2 1 
ATOM   8432  N  N   . ILE B 1 290 ? 229.189 219.578 229.194 1.00 90.87  ? 290 ILE B N   1 
ATOM   8433  C  CA  . ILE B 1 290 ? 229.785 220.097 230.418 1.00 82.57  ? 290 ILE B CA  1 
ATOM   8434  C  C   . ILE B 1 290 ? 229.465 221.575 230.568 1.00 83.88  ? 290 ILE B C   1 
ATOM   8435  O  O   . ILE B 1 290 ? 229.085 222.036 231.648 1.00 89.65  ? 290 ILE B O   1 
ATOM   8436  C  CB  . ILE B 1 290 ? 231.302 219.848 230.425 1.00 80.59  ? 290 ILE B CB  1 
ATOM   8437  C  CG1 . ILE B 1 290 ? 231.611 218.353 230.457 1.00 81.49  ? 290 ILE B CG1 1 
ATOM   8438  C  CG2 . ILE B 1 290 ? 231.941 220.531 231.612 1.00 83.84  ? 290 ILE B CG2 1 
ATOM   8439  C  CD1 . ILE B 1 290 ? 233.091 218.042 230.441 1.00 85.28  ? 290 ILE B CD1 1 
ATOM   8440  N  N   . GLU B 1 291 ? 229.594 222.335 229.484 1.00 82.73  ? 291 GLU B N   1 
ATOM   8441  C  CA  . GLU B 1 291 ? 229.303 223.761 229.548 1.00 85.63  ? 291 GLU B CA  1 
ATOM   8442  C  C   . GLU B 1 291 ? 227.849 224.007 229.913 1.00 85.65  ? 291 GLU B C   1 
ATOM   8443  O  O   . GLU B 1 291 ? 227.545 224.894 230.716 1.00 92.06  ? 291 GLU B O   1 
ATOM   8444  C  CB  . GLU B 1 291 ? 229.642 224.429 228.219 1.00 93.27  ? 291 GLU B CB  1 
ATOM   8445  C  CG  . GLU B 1 291 ? 229.578 225.946 228.266 1.00 101.91 ? 291 GLU B CG  1 
ATOM   8446  C  CD  . GLU B 1 291 ? 228.211 226.482 227.892 1.00 103.41 ? 291 GLU B CD  1 
ATOM   8447  O  OE1 . GLU B 1 291 ? 227.824 226.356 226.712 1.00 107.34 ? 291 GLU B OE1 1 
ATOM   8448  O  OE2 . GLU B 1 291 ? 227.518 227.017 228.781 1.00 101.03 ? 291 GLU B OE2 1 
ATOM   8449  N  N   . SER B 1 292 ? 226.934 223.230 229.337 1.00 83.23  ? 292 SER B N   1 
ATOM   8450  C  CA  . SER B 1 292 ? 225.537 223.330 229.732 1.00 85.21  ? 292 SER B CA  1 
ATOM   8451  C  C   . SER B 1 292 ? 225.350 222.974 231.197 1.00 89.33  ? 292 SER B C   1 
ATOM   8452  O  O   . SER B 1 292 ? 224.420 223.469 231.842 1.00 94.50  ? 292 SER B O   1 
ATOM   8453  C  CB  . SER B 1 292 ? 224.680 222.423 228.853 1.00 88.56  ? 292 SER B CB  1 
ATOM   8454  O  OG  . SER B 1 292 ? 223.304 222.581 229.145 1.00 90.21  ? 292 SER B OG  1 
ATOM   8455  N  N   . VAL B 1 293 ? 226.216 222.124 231.743 1.00 91.80  ? 293 VAL B N   1 
ATOM   8456  C  CA  . VAL B 1 293 ? 226.104 221.766 233.152 1.00 96.02  ? 293 VAL B CA  1 
ATOM   8457  C  C   . VAL B 1 293 ? 226.780 222.808 234.034 1.00 100.58 ? 293 VAL B C   1 
ATOM   8458  O  O   . VAL B 1 293 ? 226.170 223.336 234.970 1.00 100.04 ? 293 VAL B O   1 
ATOM   8459  C  CB  . VAL B 1 293 ? 226.677 220.362 233.395 1.00 94.40  ? 293 VAL B CB  1 
ATOM   8460  C  CG1 . VAL B 1 293 ? 226.910 220.142 234.876 1.00 95.95  ? 293 VAL B CG1 1 
ATOM   8461  C  CG2 . VAL B 1 293 ? 225.726 219.313 232.846 1.00 87.52  ? 293 VAL B CG2 1 
ATOM   8462  N  N   . LEU B 1 294 ? 228.043 223.120 233.756 1.00 104.46 ? 294 LEU B N   1 
ATOM   8463  C  CA  . LEU B 1 294 ? 228.784 224.117 234.523 1.00 107.48 ? 294 LEU B CA  1 
ATOM   8464  C  C   . LEU B 1 294 ? 228.672 225.463 233.818 1.00 111.54 ? 294 LEU B C   1 
ATOM   8465  O  O   . LEU B 1 294 ? 229.272 225.669 232.758 1.00 112.33 ? 294 LEU B O   1 
ATOM   8466  C  CB  . LEU B 1 294 ? 230.247 223.712 234.680 1.00 104.11 ? 294 LEU B CB  1 
ATOM   8467  C  CG  . LEU B 1 294 ? 230.531 222.423 235.442 1.00 102.54 ? 294 LEU B CG  1 
ATOM   8468  C  CD1 . LEU B 1 294 ? 232.026 222.254 235.629 1.00 105.49 ? 294 LEU B CD1 1 
ATOM   8469  C  CD2 . LEU B 1 294 ? 229.818 222.426 236.777 1.00 107.52 ? 294 LEU B CD2 1 
ATOM   8470  N  N   . ASN B 1 295 ? 227.920 226.384 234.412 1.00 113.85 ? 295 ASN B N   1 
ATOM   8471  C  CA  . ASN B 1 295 ? 227.715 227.685 233.794 1.00 115.24 ? 295 ASN B CA  1 
ATOM   8472  C  C   . ASN B 1 295 ? 228.989 228.518 233.844 1.00 117.93 ? 295 ASN B C   1 
ATOM   8473  O  O   . ASN B 1 295 ? 229.648 228.614 234.882 1.00 120.19 ? 295 ASN B O   1 
ATOM   8474  C  CB  . ASN B 1 295 ? 226.579 228.432 234.489 1.00 118.87 ? 295 ASN B CB  1 
ATOM   8475  C  CG  . ASN B 1 295 ? 226.155 229.677 233.736 1.00 120.67 ? 295 ASN B CG  1 
ATOM   8476  O  OD1 . ASN B 1 295 ? 226.569 229.898 232.598 1.00 121.10 ? 295 ASN B OD1 1 
ATOM   8477  N  ND2 . ASN B 1 295 ? 225.326 230.498 234.369 1.00 119.20 ? 295 ASN B ND2 1 
ATOM   8478  N  N   . GLU B 1 296 ? 229.331 229.117 232.703 1.00 118.16 ? 296 GLU B N   1 
ATOM   8479  C  CA  . GLU B 1 296 ? 230.439 230.066 232.595 1.00 119.97 ? 296 GLU B CA  1 
ATOM   8480  C  C   . GLU B 1 296 ? 231.751 229.448 233.074 1.00 119.30 ? 296 GLU B C   1 
ATOM   8481  O  O   . GLU B 1 296 ? 232.376 229.914 234.029 1.00 122.13 ? 296 GLU B O   1 
ATOM   8482  C  CB  . GLU B 1 296 ? 230.127 231.352 233.361 1.00 122.01 ? 296 GLU B CB  1 
ATOM   8483  C  CG  . GLU B 1 296 ? 229.330 232.374 232.566 1.00 123.80 ? 296 GLU B CG  1 
ATOM   8484  C  CD  . GLU B 1 296 ? 230.145 233.018 231.462 1.00 126.21 ? 296 GLU B CD  1 
ATOM   8485  O  OE1 . GLU B 1 296 ? 231.375 233.154 231.634 1.00 126.37 ? 296 GLU B OE1 1 
ATOM   8486  O  OE2 . GLU B 1 296 ? 229.558 233.387 230.424 1.00 126.40 ? 296 GLU B OE2 1 
ATOM   8487  N  N   . SER B 1 297 ? 232.169 228.386 232.400 1.00 113.73 ? 297 SER B N   1 
ATOM   8488  C  CA  . SER B 1 297 ? 233.394 227.679 232.744 1.00 113.39 ? 297 SER B CA  1 
ATOM   8489  C  C   . SER B 1 297 ? 234.216 227.437 231.485 1.00 108.00 ? 297 SER B C   1 
ATOM   8490  O  O   . SER B 1 297 ? 233.856 227.866 230.388 1.00 107.43 ? 297 SER B O   1 
ATOM   8491  C  CB  . SER B 1 297 ? 233.078 226.357 233.450 1.00 117.44 ? 297 SER B CB  1 
ATOM   8492  O  OG  . SER B 1 297 ? 232.187 226.558 234.533 1.00 119.71 ? 297 SER B OG  1 
ATOM   8493  N  N   . HIS B 1 298 ? 235.334 226.742 231.653 1.00 108.60 ? 298 HIS B N   1 
ATOM   8494  C  CA  . HIS B 1 298 ? 236.168 226.334 230.535 1.00 112.14 ? 298 HIS B CA  1 
ATOM   8495  C  C   . HIS B 1 298 ? 236.478 224.852 230.665 1.00 112.11 ? 298 HIS B C   1 
ATOM   8496  O  O   . HIS B 1 298 ? 236.785 224.373 231.760 1.00 115.09 ? 298 HIS B O   1 
ATOM   8497  C  CB  . HIS B 1 298 ? 237.465 227.146 230.485 1.00 118.99 ? 298 HIS B CB  1 
ATOM   8498  C  CG  . HIS B 1 298 ? 238.264 226.935 229.237 1.00 123.49 ? 298 HIS B CG  1 
ATOM   8499  N  ND1 . HIS B 1 298 ? 239.071 225.834 229.046 1.00 125.51 ? 298 HIS B ND1 1 
ATOM   8500  C  CD2 . HIS B 1 298 ? 238.381 227.686 228.116 1.00 124.84 ? 298 HIS B CD2 1 
ATOM   8501  C  CE1 . HIS B 1 298 ? 239.651 225.916 227.861 1.00 124.71 ? 298 HIS B CE1 1 
ATOM   8502  N  NE2 . HIS B 1 298 ? 239.249 227.030 227.277 1.00 125.76 ? 298 HIS B NE2 1 
ATOM   8503  N  N   . VAL B 1 299 ? 236.413 224.134 229.547 1.00 109.53 ? 299 VAL B N   1 
ATOM   8504  C  CA  . VAL B 1 299 ? 236.596 222.690 229.537 1.00 110.87 ? 299 VAL B CA  1 
ATOM   8505  C  C   . VAL B 1 299 ? 237.621 222.321 228.474 1.00 111.21 ? 299 VAL B C   1 
ATOM   8506  O  O   . VAL B 1 299 ? 237.610 222.845 227.359 1.00 116.68 ? 299 VAL B O   1 
ATOM   8507  C  CB  . VAL B 1 299 ? 235.263 221.956 229.293 1.00 109.82 ? 299 VAL B CB  1 
ATOM   8508  C  CG1 . VAL B 1 299 ? 234.520 222.590 228.130 1.00 107.79 ? 299 VAL B CG1 1 
ATOM   8509  C  CG2 . VAL B 1 299 ? 235.496 220.472 229.044 1.00 109.03 ? 299 VAL B CG2 1 
ATOM   8510  N  N   . SER B 1 300 ? 238.521 221.408 228.833 1.00 107.13 ? 300 SER B N   1 
ATOM   8511  C  CA  . SER B 1 300 ? 239.545 220.968 227.898 1.00 109.52 ? 300 SER B CA  1 
ATOM   8512  C  C   . SER B 1 300 ? 239.804 219.483 228.098 1.00 111.87 ? 300 SER B C   1 
ATOM   8513  O  O   . SER B 1 300 ? 239.671 218.961 229.209 1.00 116.44 ? 300 SER B O   1 
ATOM   8514  C  CB  . SER B 1 300 ? 240.841 221.765 228.073 1.00 114.78 ? 300 SER B CB  1 
ATOM   8515  O  OG  . SER B 1 300 ? 241.344 221.636 229.391 1.00 119.18 ? 300 SER B OG  1 
ATOM   8516  N  N   . LEU B 1 301 ? 240.189 218.812 227.014 1.00 111.75 ? 301 LEU B N   1 
ATOM   8517  C  CA  . LEU B 1 301 ? 240.394 217.372 227.019 1.00 115.59 ? 301 LEU B CA  1 
ATOM   8518  C  C   . LEU B 1 301 ? 241.682 217.014 226.293 1.00 116.46 ? 301 LEU B C   1 
ATOM   8519  O  O   . LEU B 1 301 ? 242.015 217.608 225.264 1.00 117.63 ? 301 LEU B O   1 
ATOM   8520  C  CB  . LEU B 1 301 ? 239.220 216.644 226.354 1.00 119.48 ? 301 LEU B CB  1 
ATOM   8521  C  CG  . LEU B 1 301 ? 237.811 216.908 226.888 1.00 116.74 ? 301 LEU B CG  1 
ATOM   8522  C  CD1 . LEU B 1 301 ? 236.781 216.657 225.802 1.00 108.25 ? 301 LEU B CD1 1 
ATOM   8523  C  CD2 . LEU B 1 301 ? 237.530 216.044 228.103 1.00 117.69 ? 301 LEU B CD2 1 
ATOM   8524  N  N   . PHE B 1 302 ? 242.391 216.019 226.814 1.00 118.11 ? 302 PHE B N   1 
ATOM   8525  C  CA  . PHE B 1 302 ? 243.557 215.476 226.139 1.00 123.91 ? 302 PHE B CA  1 
ATOM   8526  C  C   . PHE B 1 302 ? 243.498 213.960 226.227 1.00 129.65 ? 302 PHE B C   1 
ATOM   8527  O  O   . PHE B 1 302 ? 243.106 213.414 227.261 1.00 129.05 ? 302 PHE B O   1 
ATOM   8528  C  CB  . PHE B 1 302 ? 244.861 215.989 226.762 1.00 128.72 ? 302 PHE B CB  1 
ATOM   8529  C  CG  . PHE B 1 302 ? 244.906 217.481 226.942 1.00 129.83 ? 302 PHE B CG  1 
ATOM   8530  C  CD1 . PHE B 1 302 ? 244.376 218.075 228.076 1.00 127.84 ? 302 PHE B CD1 1 
ATOM   8531  C  CD2 . PHE B 1 302 ? 245.486 218.289 225.979 1.00 129.15 ? 302 PHE B CD2 1 
ATOM   8532  C  CE1 . PHE B 1 302 ? 244.419 219.446 228.243 1.00 126.49 ? 302 PHE B CE1 1 
ATOM   8533  C  CE2 . PHE B 1 302 ? 245.532 219.661 226.139 1.00 126.43 ? 302 PHE B CE2 1 
ATOM   8534  C  CZ  . PHE B 1 302 ? 244.998 220.240 227.274 1.00 126.76 ? 302 PHE B CZ  1 
ATOM   8535  N  N   . ALA B 1 303 ? 243.895 213.287 225.151 1.00 136.42 ? 303 ALA B N   1 
ATOM   8536  C  CA  . ALA B 1 303 ? 243.882 211.833 225.087 1.00 143.19 ? 303 ALA B CA  1 
ATOM   8537  C  C   . ALA B 1 303 ? 245.276 211.310 224.768 1.00 144.53 ? 303 ALA B C   1 
ATOM   8538  O  O   . ALA B 1 303 ? 246.081 211.994 224.135 1.00 144.90 ? 303 ALA B O   1 
ATOM   8539  C  CB  . ALA B 1 303 ? 242.885 211.330 224.036 1.00 139.82 ? 303 ALA B CB  1 
ATOM   8540  N  N   . LEU B 1 304 ? 245.557 210.085 225.206 1.00 144.08 ? 304 LEU B N   1 
ATOM   8541  C  CA  . LEU B 1 304 ? 246.875 209.490 225.016 1.00 146.85 ? 304 LEU B CA  1 
ATOM   8542  C  C   . LEU B 1 304 ? 246.964 208.895 223.617 1.00 149.70 ? 304 LEU B C   1 
ATOM   8543  O  O   . LEU B 1 304 ? 246.358 207.856 223.335 1.00 149.16 ? 304 LEU B O   1 
ATOM   8544  C  CB  . LEU B 1 304 ? 247.138 208.426 226.078 1.00 144.70 ? 304 LEU B CB  1 
ATOM   8545  C  CG  . LEU B 1 304 ? 247.442 208.921 227.492 1.00 145.10 ? 304 LEU B CG  1 
ATOM   8546  C  CD1 . LEU B 1 304 ? 247.924 207.775 228.365 1.00 143.71 ? 304 LEU B CD1 1 
ATOM   8547  C  CD2 . LEU B 1 304 ? 248.469 210.041 227.462 1.00 147.42 ? 304 LEU B CD2 1 
ATOM   8548  N  N   . ARG B 1 305 ? 247.717 209.550 222.739 1.00 151.88 ? 305 ARG B N   1 
ATOM   8549  C  CA  . ARG B 1 305 ? 247.988 209.051 221.400 1.00 151.50 ? 305 ARG B CA  1 
ATOM   8550  C  C   . ARG B 1 305 ? 249.468 208.714 221.294 1.00 154.50 ? 305 ARG B C   1 
ATOM   8551  O  O   . ARG B 1 305 ? 250.320 209.507 221.710 1.00 155.20 ? 305 ARG B O   1 
ATOM   8552  C  CB  . ARG B 1 305 ? 247.595 210.077 220.336 1.00 147.43 ? 305 ARG B CB  1 
ATOM   8553  C  CG  . ARG B 1 305 ? 246.097 210.203 220.118 1.00 145.07 ? 305 ARG B CG  1 
ATOM   8554  C  CD  . ARG B 1 305 ? 245.787 211.088 218.922 1.00 145.36 ? 305 ARG B CD  1 
ATOM   8555  N  NE  . ARG B 1 305 ? 244.378 211.030 218.551 1.00 145.90 ? 305 ARG B NE  1 
ATOM   8556  C  CZ  . ARG B 1 305 ? 243.846 210.097 217.774 1.00 143.29 ? 305 ARG B CZ  1 
ATOM   8557  N  NH1 . ARG B 1 305 ? 244.581 209.122 217.262 1.00 143.28 ? 305 ARG B NH1 1 
ATOM   8558  N  NH2 . ARG B 1 305 ? 242.545 210.142 217.502 1.00 137.94 ? 305 ARG B NH2 1 
ATOM   8559  N  N   . ASN B 1 306 ? 249.764 207.529 220.763 1.00 154.08 ? 306 ASN B N   1 
ATOM   8560  C  CA  . ASN B 1 306 ? 251.118 207.013 220.584 1.00 154.36 ? 306 ASN B CA  1 
ATOM   8561  C  C   . ASN B 1 306 ? 251.916 206.972 221.882 1.00 156.35 ? 306 ASN B C   1 
ATOM   8562  O  O   . ASN B 1 306 ? 253.142 206.816 221.844 1.00 156.60 ? 306 ASN B O   1 
ATOM   8563  C  CB  . ASN B 1 306 ? 251.890 207.818 219.529 1.00 154.65 ? 306 ASN B CB  1 
ATOM   8564  C  CG  . ASN B 1 306 ? 251.172 207.869 218.195 1.00 152.13 ? 306 ASN B CG  1 
ATOM   8565  O  OD1 . ASN B 1 306 ? 250.445 206.945 217.832 1.00 151.17 ? 306 ASN B OD1 1 
ATOM   8566  N  ND2 . ASN B 1 306 ? 251.375 208.953 217.455 1.00 149.79 ? 306 ASN B ND2 1 
ATOM   8567  N  N   . GLY B 1 307 ? 251.256 207.096 223.032 1.00 155.56 ? 307 GLY B N   1 
ATOM   8568  C  CA  . GLY B 1 307 ? 251.933 207.108 224.310 1.00 155.88 ? 307 GLY B CA  1 
ATOM   8569  C  C   . GLY B 1 307 ? 252.090 208.468 224.957 1.00 157.81 ? 307 GLY B C   1 
ATOM   8570  O  O   . GLY B 1 307 ? 252.563 208.534 226.099 1.00 156.00 ? 307 GLY B O   1 
ATOM   8571  N  N   . MET B 1 308 ? 251.715 209.549 224.279 1.00 159.64 ? 308 MET B N   1 
ATOM   8572  C  CA  . MET B 1 308 ? 251.828 210.874 224.867 1.00 157.31 ? 308 MET B CA  1 
ATOM   8573  C  C   . MET B 1 308 ? 250.485 211.585 224.810 1.00 155.15 ? 308 MET B C   1 
ATOM   8574  O  O   . MET B 1 308 ? 249.667 211.307 223.929 1.00 152.07 ? 308 MET B O   1 
ATOM   8575  C  CB  . MET B 1 308 ? 252.884 211.727 224.147 1.00 156.78 ? 308 MET B CB  1 
ATOM   8576  C  CG  . MET B 1 308 ? 252.924 211.556 222.639 1.00 159.36 ? 308 MET B CG  1 
ATOM   8577  S  SD  . MET B 1 308 ? 253.510 209.931 222.135 1.00 170.15 ? 308 MET B SD  1 
ATOM   8578  C  CE  . MET B 1 308 ? 255.149 209.925 222.857 1.00 162.05 ? 308 MET B CE  1 
ATOM   8579  N  N   . PRO B 1 309 ? 250.226 212.501 225.744 1.00 154.54 ? 309 PRO B N   1 
ATOM   8580  C  CA  . PRO B 1 309 ? 248.961 213.247 225.706 1.00 150.89 ? 309 PRO B CA  1 
ATOM   8581  C  C   . PRO B 1 309 ? 248.937 214.225 224.540 1.00 146.34 ? 309 PRO B C   1 
ATOM   8582  O  O   . PRO B 1 309 ? 249.904 214.950 224.296 1.00 147.71 ? 309 PRO B O   1 
ATOM   8583  C  CB  . PRO B 1 309 ? 248.933 213.974 227.055 1.00 150.37 ? 309 PRO B CB  1 
ATOM   8584  C  CG  . PRO B 1 309 ? 250.364 214.068 227.463 1.00 149.85 ? 309 PRO B CG  1 
ATOM   8585  C  CD  . PRO B 1 309 ? 251.027 212.828 226.936 1.00 150.88 ? 309 PRO B CD  1 
ATOM   8586  N  N   . ILE B 1 310 ? 247.819 214.234 223.819 1.00 141.01 ? 310 ILE B N   1 
ATOM   8587  C  CA  . ILE B 1 310 ? 247.592 215.127 222.692 1.00 138.87 ? 310 ILE B CA  1 
ATOM   8588  C  C   . ILE B 1 310 ? 246.191 215.700 222.831 1.00 133.72 ? 310 ILE B C   1 
ATOM   8589  O  O   . ILE B 1 310 ? 245.264 215.000 223.252 1.00 132.71 ? 310 ILE B O   1 
ATOM   8590  C  CB  . ILE B 1 310 ? 247.767 214.401 221.339 1.00 140.26 ? 310 ILE B CB  1 
ATOM   8591  C  CG1 . ILE B 1 310 ? 249.221 213.962 221.153 1.00 144.08 ? 310 ILE B CG1 1 
ATOM   8592  C  CG2 . ILE B 1 310 ? 247.337 215.288 220.180 1.00 135.73 ? 310 ILE B CG2 1 
ATOM   8593  C  CD1 . ILE B 1 310 ? 249.457 213.138 219.908 1.00 143.06 ? 310 ILE B CD1 1 
ATOM   8594  N  N   . HIS B 1 311 ? 246.047 216.979 222.499 1.00 129.70 ? 311 HIS B N   1 
ATOM   8595  C  CA  . HIS B 1 311 ? 244.774 217.668 222.642 1.00 124.10 ? 311 HIS B CA  1 
ATOM   8596  C  C   . HIS B 1 311 ? 243.674 216.947 221.875 1.00 125.88 ? 311 HIS B C   1 
ATOM   8597  O  O   . HIS B 1 311 ? 243.852 216.584 220.709 1.00 126.59 ? 311 HIS B O   1 
ATOM   8598  C  CB  . HIS B 1 311 ? 244.923 219.099 222.138 1.00 118.82 ? 311 HIS B CB  1 
ATOM   8599  C  CG  . HIS B 1 311 ? 243.637 219.855 222.064 1.00 118.25 ? 311 HIS B CG  1 
ATOM   8600  N  ND1 . HIS B 1 311 ? 242.969 220.068 220.879 1.00 119.29 ? 311 HIS B ND1 1 
ATOM   8601  C  CD2 . HIS B 1 311 ? 242.910 220.473 223.023 1.00 117.66 ? 311 HIS B CD2 1 
ATOM   8602  C  CE1 . HIS B 1 311 ? 241.878 220.773 221.112 1.00 117.34 ? 311 HIS B CE1 1 
ATOM   8603  N  NE2 . HIS B 1 311 ? 241.819 221.034 222.405 1.00 116.58 ? 311 HIS B NE2 1 
ATOM   8604  N  N   . TRP B 1 312 ? 242.533 216.734 222.537 1.00 123.24 ? 312 TRP B N   1 
ATOM   8605  C  CA  . TRP B 1 312 ? 241.378 216.091 221.920 1.00 121.78 ? 312 TRP B CA  1 
ATOM   8606  C  C   . TRP B 1 312 ? 240.364 217.125 221.447 1.00 118.98 ? 312 TRP B C   1 
ATOM   8607  O  O   . TRP B 1 312 ? 239.986 217.140 220.273 1.00 118.61 ? 312 TRP B O   1 
ATOM   8608  C  CB  . TRP B 1 312 ? 240.735 215.112 222.914 1.00 122.19 ? 312 TRP B CB  1 
ATOM   8609  C  CG  . TRP B 1 312 ? 239.506 214.389 222.405 1.00 124.96 ? 312 TRP B CG  1 
ATOM   8610  C  CD1 . TRP B 1 312 ? 239.044 214.345 221.120 1.00 123.87 ? 312 TRP B CD1 1 
ATOM   8611  C  CD2 . TRP B 1 312 ? 238.587 213.611 223.184 1.00 124.09 ? 312 TRP B CD2 1 
ATOM   8612  N  NE1 . TRP B 1 312 ? 237.901 213.586 221.053 1.00 121.04 ? 312 TRP B NE1 1 
ATOM   8613  C  CE2 . TRP B 1 312 ? 237.599 213.127 222.306 1.00 121.37 ? 312 TRP B CE2 1 
ATOM   8614  C  CE3 . TRP B 1 312 ? 238.506 213.279 224.540 1.00 123.53 ? 312 TRP B CE3 1 
ATOM   8615  C  CZ2 . TRP B 1 312 ? 236.546 212.330 222.737 1.00 120.35 ? 312 TRP B CZ2 1 
ATOM   8616  C  CZ3 . TRP B 1 312 ? 237.458 212.486 224.966 1.00 121.73 ? 312 TRP B CZ3 1 
ATOM   8617  C  CH2 . TRP B 1 312 ? 236.492 212.021 224.067 1.00 122.32 ? 312 TRP B CH2 1 
ATOM   8618  N  N   . ALA B 1 313 ? 239.918 217.996 222.345 1.00 115.41 ? 313 ALA B N   1 
ATOM   8619  C  CA  . ALA B 1 313 ? 238.980 219.049 221.991 1.00 112.60 ? 313 ALA B CA  1 
ATOM   8620  C  C   . ALA B 1 313 ? 239.029 220.115 223.072 1.00 113.52 ? 313 ALA B C   1 
ATOM   8621  O  O   . ALA B 1 313 ? 239.641 219.932 224.127 1.00 116.10 ? 313 ALA B O   1 
ATOM   8622  C  CB  . ALA B 1 313 ? 237.561 218.502 221.814 1.00 111.88 ? 313 ALA B CB  1 
ATOM   8623  N  N   . SER B 1 314 ? 238.397 221.249 222.786 1.00 111.19 ? 314 SER B N   1 
ATOM   8624  C  CA  . SER B 1 314 ? 238.315 222.329 223.755 1.00 112.21 ? 314 SER B CA  1 
ATOM   8625  C  C   . SER B 1 314 ? 237.079 223.157 223.451 1.00 113.56 ? 314 SER B C   1 
ATOM   8626  O  O   . SER B 1 314 ? 236.493 223.057 222.371 1.00 111.59 ? 314 SER B O   1 
ATOM   8627  C  CB  . SER B 1 314 ? 239.571 223.200 223.737 1.00 115.82 ? 314 SER B CB  1 
ATOM   8628  O  OG  . SER B 1 314 ? 240.724 222.431 224.030 1.00 115.27 ? 314 SER B OG  1 
ATOM   8629  N  N   . SER B 1 315 ? 236.683 223.965 224.427 1.00 118.63 ? 315 SER B N   1 
ATOM   8630  C  CA  . SER B 1 315 ? 235.532 224.838 224.255 1.00 126.48 ? 315 SER B CA  1 
ATOM   8631  C  C   . SER B 1 315 ? 235.885 226.024 223.366 1.00 135.00 ? 315 SER B C   1 
ATOM   8632  O  O   . SER B 1 315 ? 237.047 226.425 223.256 1.00 134.27 ? 315 SER B O   1 
ATOM   8633  C  CB  . SER B 1 315 ? 235.029 225.333 225.610 1.00 124.82 ? 315 SER B CB  1 
ATOM   8634  O  OG  . SER B 1 315 ? 236.084 225.891 226.373 1.00 124.76 ? 315 SER B OG  1 
ATOM   8635  N  N   . SER B 1 316 ? 234.859 226.586 222.723 1.00 139.70 ? 316 SER B N   1 
ATOM   8636  C  CA  . SER B 1 316 ? 235.070 227.755 221.876 1.00 139.18 ? 316 SER B CA  1 
ATOM   8637  C  C   . SER B 1 316 ? 235.403 228.994 222.698 1.00 141.30 ? 316 SER B C   1 
ATOM   8638  O  O   . SER B 1 316 ? 236.055 229.914 222.190 1.00 140.12 ? 316 SER B O   1 
ATOM   8639  C  CB  . SER B 1 316 ? 233.834 228.009 221.012 1.00 137.64 ? 316 SER B CB  1 
ATOM   8640  O  OG  . SER B 1 316 ? 232.677 228.179 221.812 1.00 138.78 ? 316 SER B OG  1 
ATOM   8641  N  N   . HIS B 1 317 ? 234.967 229.039 223.954 1.00 140.92 ? 317 HIS B N   1 
ATOM   8642  C  CA  . HIS B 1 317 ? 235.256 230.183 224.807 1.00 137.92 ? 317 HIS B CA  1 
ATOM   8643  C  C   . HIS B 1 317 ? 236.742 230.241 225.142 1.00 138.60 ? 317 HIS B C   1 
ATOM   8644  O  O   . HIS B 1 317 ? 237.377 229.217 225.409 1.00 136.77 ? 317 HIS B O   1 
ATOM   8645  C  CB  . HIS B 1 317 ? 234.432 230.113 226.093 1.00 135.64 ? 317 HIS B CB  1 
ATOM   8646  C  CG  . HIS B 1 317 ? 232.988 229.787 225.871 1.00 138.87 ? 317 HIS B CG  1 
ATOM   8647  N  ND1 . HIS B 1 317 ? 232.543 228.507 225.617 1.00 138.71 ? 317 HIS B ND1 1 
ATOM   8648  C  CD2 . HIS B 1 317 ? 231.887 230.575 225.866 1.00 137.32 ? 317 HIS B CD2 1 
ATOM   8649  C  CE1 . HIS B 1 317 ? 231.231 228.521 225.464 1.00 132.69 ? 317 HIS B CE1 1 
ATOM   8650  N  NE2 . HIS B 1 317 ? 230.808 229.764 225.611 1.00 131.94 ? 317 HIS B NE2 1 
ATOM   8651  N  N   . GLY B 1 318 ? 237.295 231.451 225.125 1.00 142.05 ? 318 GLY B N   1 
ATOM   8652  C  CA  . GLY B 1 318 ? 238.699 231.644 225.431 1.00 143.13 ? 318 GLY B CA  1 
ATOM   8653  C  C   . GLY B 1 318 ? 238.966 232.900 226.234 1.00 143.52 ? 318 GLY B C   1 
ATOM   8654  O  O   . GLY B 1 318 ? 240.113 233.346 226.338 1.00 141.35 ? 318 GLY B O   1 
ATOM   8655  N  N   . ALA B 1 319 ? 237.915 233.478 226.807 1.00 145.50 ? 319 ALA B N   1 
ATOM   8656  C  CA  . ALA B 1 319 ? 238.054 234.695 227.588 1.00 148.73 ? 319 ALA B CA  1 
ATOM   8657  C  C   . ALA B 1 319 ? 238.639 234.391 228.964 1.00 153.98 ? 319 ALA B C   1 
ATOM   8658  O  O   . ALA B 1 319 ? 238.608 233.256 229.449 1.00 153.22 ? 319 ALA B O   1 
ATOM   8659  C  CB  . ALA B 1 319 ? 236.704 235.398 227.736 1.00 146.25 ? 319 ALA B CB  1 
ATOM   8660  N  N   . GLU B 1 320 ? 239.184 235.430 229.592 1.00 156.48 ? 320 GLU B N   1 
ATOM   8661  C  CA  . GLU B 1 320 ? 239.754 235.290 230.923 1.00 159.59 ? 320 GLU B CA  1 
ATOM   8662  C  C   . GLU B 1 320 ? 238.663 235.010 231.951 1.00 163.56 ? 320 GLU B C   1 
ATOM   8663  O  O   . GLU B 1 320 ? 237.520 235.456 231.818 1.00 164.12 ? 320 GLU B O   1 
ATOM   8664  C  CB  . GLU B 1 320 ? 240.525 236.553 231.309 1.00 158.81 ? 320 GLU B CB  1 
ATOM   8665  C  CG  . GLU B 1 320 ? 241.692 236.872 230.388 1.00 156.71 ? 320 GLU B CG  1 
ATOM   8666  C  CD  . GLU B 1 320 ? 242.423 238.137 230.792 1.00 157.33 ? 320 GLU B CD  1 
ATOM   8667  O  OE1 . GLU B 1 320 ? 242.394 238.485 231.991 1.00 160.32 ? 320 GLU B OE1 1 
ATOM   8668  O  OE2 . GLU B 1 320 ? 243.026 238.784 229.910 1.00 152.91 ? 320 GLU B OE2 1 
ATOM   8669  N  N   . ILE B 1 321 ? 239.030 234.260 232.987 1.00 164.77 ? 321 ILE B N   1 
ATOM   8670  C  CA  . ILE B 1 321 ? 238.112 233.874 234.053 1.00 162.72 ? 321 ILE B CA  1 
ATOM   8671  C  C   . ILE B 1 321 ? 238.616 234.484 235.353 1.00 164.94 ? 321 ILE B C   1 
ATOM   8672  O  O   . ILE B 1 321 ? 239.765 234.251 235.750 1.00 164.05 ? 321 ILE B O   1 
ATOM   8673  C  CB  . ILE B 1 321 ? 237.988 232.347 234.176 1.00 156.67 ? 321 ILE B CB  1 
ATOM   8674  C  CG1 . ILE B 1 321 ? 237.535 231.740 232.847 1.00 150.63 ? 321 ILE B CG1 1 
ATOM   8675  C  CG2 . ILE B 1 321 ? 237.021 231.980 235.289 1.00 154.35 ? 321 ILE B CG2 1 
ATOM   8676  C  CD1 . ILE B 1 321 ? 237.614 230.229 232.808 1.00 139.13 ? 321 ILE B CD1 1 
ATOM   8677  N  N   . GLN B 1 322 ? 237.761 235.262 236.011 1.00 167.09 ? 322 GLN B N   1 
ATOM   8678  C  CA  . GLN B 1 322 ? 238.118 235.881 237.280 1.00 165.43 ? 322 GLN B CA  1 
ATOM   8679  C  C   . GLN B 1 322 ? 237.953 234.885 238.420 1.00 160.42 ? 322 GLN B C   1 
ATOM   8680  O  O   . GLN B 1 322 ? 236.945 234.177 238.503 1.00 159.51 ? 322 GLN B O   1 
ATOM   8681  C  CB  . GLN B 1 322 ? 237.254 237.117 237.533 1.00 166.85 ? 322 GLN B CB  1 
ATOM   8682  C  CG  . GLN B 1 322 ? 237.446 238.227 236.512 1.00 168.04 ? 322 GLN B CG  1 
ATOM   8683  C  CD  . GLN B 1 322 ? 236.640 239.468 236.843 1.00 166.79 ? 322 GLN B CD  1 
ATOM   8684  O  OE1 . GLN B 1 322 ? 235.831 239.468 237.771 1.00 167.12 ? 322 GLN B OE1 1 
ATOM   8685  N  NE2 . GLN B 1 322 ? 236.856 240.534 236.082 1.00 162.91 ? 322 GLN B NE2 1 
ATOM   8686  N  N   . ASN B 1 323 ? 238.952 234.841 239.303 1.00 157.95 ? 323 ASN B N   1 
ATOM   8687  C  CA  . ASN B 1 323 ? 238.978 233.911 240.432 1.00 156.42 ? 323 ASN B CA  1 
ATOM   8688  C  C   . ASN B 1 323 ? 238.808 232.470 239.955 1.00 155.17 ? 323 ASN B C   1 
ATOM   8689  O  O   . ASN B 1 323 ? 238.051 231.680 240.523 1.00 151.54 ? 323 ASN B O   1 
ATOM   8690  C  CB  . ASN B 1 323 ? 237.916 234.278 241.471 1.00 156.84 ? 323 ASN B CB  1 
ATOM   8691  C  CG  . ASN B 1 323 ? 237.973 235.739 241.872 1.00 157.58 ? 323 ASN B CG  1 
ATOM   8692  O  OD1 . ASN B 1 323 ? 239.044 236.345 241.905 1.00 159.07 ? 323 ASN B OD1 1 
ATOM   8693  N  ND2 . ASN B 1 323 ? 236.815 236.314 242.179 1.00 154.93 ? 323 ASN B ND2 1 
ATOM   8694  N  N   . ALA B 1 324 ? 239.526 232.134 238.886 1.00 157.87 ? 324 ALA B N   1 
ATOM   8695  C  CA  . ALA B 1 324 ? 239.394 230.821 238.271 1.00 154.55 ? 324 ALA B CA  1 
ATOM   8696  C  C   . ALA B 1 324 ? 239.928 229.728 239.188 1.00 151.70 ? 324 ALA B C   1 
ATOM   8697  O  O   . ALA B 1 324 ? 240.967 229.885 239.834 1.00 150.07 ? 324 ALA B O   1 
ATOM   8698  C  CB  . ALA B 1 324 ? 240.131 230.787 236.933 1.00 151.68 ? 324 ALA B CB  1 
ATOM   8699  N  N   . GLN B 1 325 ? 239.204 228.613 239.238 1.00 147.83 ? 325 GLN B N   1 
ATOM   8700  C  CA  . GLN B 1 325 ? 239.611 227.427 239.977 1.00 143.65 ? 325 GLN B CA  1 
ATOM   8701  C  C   . GLN B 1 325 ? 239.696 226.262 239.004 1.00 142.43 ? 325 GLN B C   1 
ATOM   8702  O  O   . GLN B 1 325 ? 238.740 225.994 238.270 1.00 139.27 ? 325 GLN B O   1 
ATOM   8703  C  CB  . GLN B 1 325 ? 238.624 227.115 241.103 1.00 141.12 ? 325 GLN B CB  1 
ATOM   8704  C  CG  . GLN B 1 325 ? 238.399 228.271 242.060 1.00 145.02 ? 325 GLN B CG  1 
ATOM   8705  C  CD  . GLN B 1 325 ? 237.312 227.982 243.075 1.00 143.63 ? 325 GLN B CD  1 
ATOM   8706  O  OE1 . GLN B 1 325 ? 236.328 227.307 242.773 1.00 141.96 ? 325 GLN B OE1 1 
ATOM   8707  N  NE2 . GLN B 1 325 ? 237.484 228.494 244.289 1.00 142.93 ? 325 GLN B NE2 1 
ATOM   8708  N  N   . SER B 1 326 ? 240.833 225.572 239.000 1.00 144.37 ? 326 SER B N   1 
ATOM   8709  C  CA  . SER B 1 326 ? 241.109 224.527 238.025 1.00 143.19 ? 326 SER B CA  1 
ATOM   8710  C  C   . SER B 1 326 ? 241.174 223.164 238.700 1.00 144.54 ? 326 SER B C   1 
ATOM   8711  O  O   . SER B 1 326 ? 241.785 223.012 239.763 1.00 143.29 ? 326 SER B O   1 
ATOM   8712  C  CB  . SER B 1 326 ? 242.420 224.799 237.283 1.00 140.54 ? 326 SER B CB  1 
ATOM   8713  O  OG  . SER B 1 326 ? 242.632 223.840 236.261 1.00 137.87 ? 326 SER B OG  1 
ATOM   8714  N  N   . TRP B 1 327 ? 240.538 222.176 238.073 1.00 142.49 ? 327 TRP B N   1 
ATOM   8715  C  CA  . TRP B 1 327 ? 240.565 220.794 238.530 1.00 138.71 ? 327 TRP B CA  1 
ATOM   8716  C  C   . TRP B 1 327 ? 241.041 219.914 237.386 1.00 135.78 ? 327 TRP B C   1 
ATOM   8717  O  O   . TRP B 1 327 ? 240.479 219.961 236.288 1.00 134.27 ? 327 TRP B O   1 
ATOM   8718  C  CB  . TRP B 1 327 ? 239.185 220.341 239.012 1.00 132.96 ? 327 TRP B CB  1 
ATOM   8719  C  CG  . TRP B 1 327 ? 238.404 221.442 239.638 1.00 136.46 ? 327 TRP B CG  1 
ATOM   8720  C  CD1 . TRP B 1 327 ? 237.556 222.303 239.010 1.00 136.87 ? 327 TRP B CD1 1 
ATOM   8721  C  CD2 . TRP B 1 327 ? 238.404 221.816 241.020 1.00 139.86 ? 327 TRP B CD2 1 
ATOM   8722  N  NE1 . TRP B 1 327 ? 237.022 223.187 239.913 1.00 139.88 ? 327 TRP B NE1 1 
ATOM   8723  C  CE2 . TRP B 1 327 ? 237.527 222.910 241.155 1.00 141.43 ? 327 TRP B CE2 1 
ATOM   8724  C  CE3 . TRP B 1 327 ? 239.057 221.330 242.156 1.00 137.04 ? 327 TRP B CE3 1 
ATOM   8725  C  CZ2 . TRP B 1 327 ? 237.286 223.526 242.381 1.00 137.50 ? 327 TRP B CZ2 1 
ATOM   8726  C  CZ3 . TRP B 1 327 ? 238.817 221.944 243.373 1.00 135.48 ? 327 TRP B CZ3 1 
ATOM   8727  C  CH2 . TRP B 1 327 ? 237.939 223.030 243.476 1.00 133.99 ? 327 TRP B CH2 1 
ATOM   8728  N  N   . SER B 1 328 ? 242.070 219.116 237.643 1.00 134.68 ? 328 SER B N   1 
ATOM   8729  C  CA  . SER B 1 328 ? 242.637 218.218 236.648 1.00 132.59 ? 328 SER B CA  1 
ATOM   8730  C  C   . SER B 1 328 ? 242.339 216.782 237.047 1.00 134.59 ? 328 SER B C   1 
ATOM   8731  O  O   . SER B 1 328 ? 242.680 216.357 238.157 1.00 136.36 ? 328 SER B O   1 
ATOM   8732  C  CB  . SER B 1 328 ? 244.146 218.431 236.511 1.00 133.07 ? 328 SER B CB  1 
ATOM   8733  O  OG  . SER B 1 328 ? 244.714 217.488 235.618 1.00 133.54 ? 328 SER B OG  1 
ATOM   8734  N  N   . ALA B 1 329 ? 241.708 216.039 236.144 1.00 132.07 ? 329 ALA B N   1 
ATOM   8735  C  CA  . ALA B 1 329 ? 241.352 214.649 236.379 1.00 129.76 ? 329 ALA B CA  1 
ATOM   8736  C  C   . ALA B 1 329 ? 241.986 213.775 235.309 1.00 128.22 ? 329 ALA B C   1 
ATOM   8737  O  O   . ALA B 1 329 ? 241.914 214.084 234.115 1.00 126.68 ? 329 ALA B O   1 
ATOM   8738  C  CB  . ALA B 1 329 ? 239.833 214.456 236.384 1.00 125.57 ? 329 ALA B CB  1 
ATOM   8739  N  N   . THR B 1 330 ? 242.610 212.685 235.743 1.00 130.09 ? 330 THR B N   1 
ATOM   8740  C  CA  . THR B 1 330 ? 243.251 211.746 234.834 1.00 131.69 ? 330 THR B CA  1 
ATOM   8741  C  C   . THR B 1 330 ? 242.257 210.653 234.467 1.00 132.98 ? 330 THR B C   1 
ATOM   8742  O  O   . THR B 1 330 ? 241.787 209.914 235.340 1.00 135.38 ? 330 THR B O   1 
ATOM   8743  C  CB  . THR B 1 330 ? 244.502 211.140 235.467 1.00 129.46 ? 330 THR B CB  1 
ATOM   8744  O  OG1 . THR B 1 330 ? 245.483 212.165 235.669 1.00 126.28 ? 330 THR B OG1 1 
ATOM   8745  C  CG2 . THR B 1 330 ? 245.083 210.057 234.568 1.00 131.05 ? 330 THR B CG2 1 
ATOM   8746  N  N   . ILE B 1 331 ? 241.937 210.553 233.177 1.00 131.50 ? 331 ILE B N   1 
ATOM   8747  C  CA  . ILE B 1 331 ? 241.018 209.525 232.711 1.00 133.38 ? 331 ILE B CA  1 
ATOM   8748  C  C   . ILE B 1 331 ? 241.671 208.158 232.850 1.00 137.74 ? 331 ILE B C   1 
ATOM   8749  O  O   . ILE B 1 331 ? 242.830 207.960 232.466 1.00 138.52 ? 331 ILE B O   1 
ATOM   8750  C  CB  . ILE B 1 331 ? 240.603 209.803 231.257 1.00 130.30 ? 331 ILE B CB  1 
ATOM   8751  C  CG1 . ILE B 1 331 ? 239.906 211.161 231.153 1.00 124.59 ? 331 ILE B CG1 1 
ATOM   8752  C  CG2 . ILE B 1 331 ? 239.704 208.700 230.736 1.00 125.08 ? 331 ILE B CG2 1 
ATOM   8753  C  CD1 . ILE B 1 331 ? 239.905 211.741 229.756 1.00 123.72 ? 331 ILE B CD1 1 
ATOM   8754  N  N   . ARG B 1 332 ? 240.930 207.204 233.408 1.00 140.93 ? 332 ARG B N   1 
ATOM   8755  C  CA  . ARG B 1 332 ? 241.423 205.848 233.596 1.00 146.37 ? 332 ARG B CA  1 
ATOM   8756  C  C   . ARG B 1 332 ? 240.459 204.857 232.962 1.00 148.61 ? 332 ARG B C   1 
ATOM   8757  O  O   . ARG B 1 332 ? 239.238 205.021 233.050 1.00 146.88 ? 332 ARG B O   1 
ATOM   8758  C  CB  . ARG B 1 332 ? 241.611 205.523 235.081 1.00 146.43 ? 332 ARG B CB  1 
ATOM   8759  C  CG  . ARG B 1 332 ? 242.794 206.235 235.717 1.00 147.95 ? 332 ARG B CG  1 
ATOM   8760  C  CD  . ARG B 1 332 ? 242.974 205.826 237.169 1.00 153.62 ? 332 ARG B CD  1 
ATOM   8761  N  NE  . ARG B 1 332 ? 244.110 206.501 237.785 1.00 157.74 ? 332 ARG B NE  1 
ATOM   8762  C  CZ  . ARG B 1 332 ? 245.356 206.048 237.755 1.00 156.35 ? 332 ARG B CZ  1 
ATOM   8763  N  NH1 . ARG B 1 332 ? 245.666 204.917 237.144 1.00 154.21 ? 332 ARG B NH1 1 
ATOM   8764  N  NH2 . ARG B 1 332 ? 246.316 206.749 238.353 1.00 155.15 ? 332 ARG B NH2 1 
ATOM   8765  N  N   . GLN B 1 333 ? 241.014 203.830 232.325 1.00 151.38 ? 333 GLN B N   1 
ATOM   8766  C  CA  . GLN B 1 333 ? 240.214 202.818 231.650 1.00 152.29 ? 333 GLN B CA  1 
ATOM   8767  C  C   . GLN B 1 333 ? 239.772 201.757 232.657 1.00 156.34 ? 333 GLN B C   1 
ATOM   8768  O  O   . GLN B 1 333 ? 239.960 201.895 233.869 1.00 157.00 ? 333 GLN B O   1 
ATOM   8769  C  CB  . GLN B 1 333 ? 240.998 202.211 230.490 1.00 152.20 ? 333 GLN B CB  1 
ATOM   8770  C  CG  . GLN B 1 333 ? 241.265 203.170 229.344 1.00 148.61 ? 333 GLN B CG  1 
ATOM   8771  C  CD  . GLN B 1 333 ? 242.049 202.523 228.219 1.00 145.72 ? 333 GLN B CD  1 
ATOM   8772  O  OE1 . GLN B 1 333 ? 242.163 201.299 228.151 1.00 145.42 ? 333 GLN B OE1 1 
ATOM   8773  N  NE2 . GLN B 1 333 ? 242.591 203.344 227.327 1.00 142.01 ? 333 GLN B NE2 1 
ATOM   8774  N  N   . ARG B 1 334 ? 239.169 200.676 232.155 1.00 156.72 ? 334 ARG B N   1 
ATOM   8775  C  CA  . ARG B 1 334 ? 238.733 199.593 233.031 1.00 156.73 ? 334 ARG B CA  1 
ATOM   8776  C  C   . ARG B 1 334 ? 239.918 198.936 233.725 1.00 158.68 ? 334 ARG B C   1 
ATOM   8777  O  O   . ARG B 1 334 ? 239.853 198.619 234.918 1.00 158.57 ? 334 ARG B O   1 
ATOM   8778  C  CB  . ARG B 1 334 ? 237.943 198.557 232.232 1.00 150.91 ? 334 ARG B CB  1 
ATOM   8779  C  CG  . ARG B 1 334 ? 236.672 199.088 231.592 1.00 144.42 ? 334 ARG B CG  1 
ATOM   8780  C  CD  . ARG B 1 334 ? 235.881 197.964 230.941 1.00 139.18 ? 334 ARG B CD  1 
ATOM   8781  N  NE  . ARG B 1 334 ? 234.848 198.465 230.043 1.00 134.35 ? 334 ARG B NE  1 
ATOM   8782  C  CZ  . ARG B 1 334 ? 233.586 198.058 230.051 1.00 125.34 ? 334 ARG B CZ  1 
ATOM   8783  N  NH1 . ARG B 1 334 ? 233.159 197.146 230.908 1.00 119.97 ? 334 ARG B NH1 1 
ATOM   8784  N  NH2 . ARG B 1 334 ? 232.732 198.579 229.175 1.00 121.90 ? 334 ARG B NH2 1 
ATOM   8785  N  N   . ASP B 1 335 ? 241.012 198.725 232.992 1.00 159.83 ? 335 ASP B N   1 
ATOM   8786  C  CA  . ASP B 1 335 ? 242.205 198.109 233.557 1.00 159.53 ? 335 ASP B CA  1 
ATOM   8787  C  C   . ASP B 1 335 ? 242.956 199.034 234.505 1.00 160.68 ? 335 ASP B C   1 
ATOM   8788  O  O   . ASP B 1 335 ? 243.885 198.577 235.179 1.00 158.83 ? 335 ASP B O   1 
ATOM   8789  C  CB  . ASP B 1 335 ? 243.136 197.653 232.432 1.00 157.93 ? 335 ASP B CB  1 
ATOM   8790  C  CG  . ASP B 1 335 ? 243.363 198.732 231.391 1.00 155.82 ? 335 ASP B CG  1 
ATOM   8791  O  OD1 . ASP B 1 335 ? 242.864 199.860 231.583 1.00 154.95 ? 335 ASP B OD1 1 
ATOM   8792  O  OD2 . ASP B 1 335 ? 244.040 198.451 230.380 1.00 154.55 ? 335 ASP B OD2 1 
ATOM   8793  N  N   . GLY B 1 336 ? 242.582 200.310 234.572 1.00 160.59 ? 336 GLY B N   1 
ATOM   8794  C  CA  . GLY B 1 336 ? 243.264 201.269 235.408 1.00 156.33 ? 336 GLY B CA  1 
ATOM   8795  C  C   . GLY B 1 336 ? 244.396 202.011 234.735 1.00 154.40 ? 336 GLY B C   1 
ATOM   8796  O  O   . GLY B 1 336 ? 244.951 202.940 235.337 1.00 152.66 ? 336 GLY B O   1 
ATOM   8797  N  N   . ALA B 1 337 ? 244.761 201.633 233.514 1.00 155.91 ? 337 ALA B N   1 
ATOM   8798  C  CA  . ALA B 1 337 ? 245.801 202.353 232.799 1.00 154.49 ? 337 ALA B CA  1 
ATOM   8799  C  C   . ALA B 1 337 ? 245.305 203.747 232.422 1.00 151.90 ? 337 ALA B C   1 
ATOM   8800  O  O   . ALA B 1 337 ? 244.149 203.908 232.019 1.00 149.05 ? 337 ALA B O   1 
ATOM   8801  C  CB  . ALA B 1 337 ? 246.220 201.589 231.544 1.00 151.82 ? 337 ALA B CB  1 
ATOM   8802  N  N   . PRO B 1 338 ? 246.146 204.769 232.550 1.00 153.89 ? 338 PRO B N   1 
ATOM   8803  C  CA  . PRO B 1 338 ? 245.726 206.118 232.161 1.00 150.46 ? 338 PRO B CA  1 
ATOM   8804  C  C   . PRO B 1 338 ? 245.463 206.210 230.667 1.00 147.21 ? 338 PRO B C   1 
ATOM   8805  O  O   . PRO B 1 338 ? 246.101 205.537 229.854 1.00 144.19 ? 338 PRO B O   1 
ATOM   8806  C  CB  . PRO B 1 338 ? 246.914 206.995 232.572 1.00 149.67 ? 338 PRO B CB  1 
ATOM   8807  C  CG  . PRO B 1 338 ? 248.081 206.064 232.594 1.00 152.53 ? 338 PRO B CG  1 
ATOM   8808  C  CD  . PRO B 1 338 ? 247.537 204.736 233.034 1.00 154.69 ? 338 PRO B CD  1 
ATOM   8809  N  N   . ALA B 1 339 ? 244.498 207.055 230.313 1.00 144.09 ? 339 ALA B N   1 
ATOM   8810  C  CA  . ALA B 1 339 ? 244.139 207.268 228.916 1.00 140.93 ? 339 ALA B CA  1 
ATOM   8811  C  C   . ALA B 1 339 ? 243.941 208.726 228.538 1.00 137.28 ? 339 ALA B C   1 
ATOM   8812  O  O   . ALA B 1 339 ? 243.924 209.028 227.340 1.00 138.15 ? 339 ALA B O   1 
ATOM   8813  C  CB  . ALA B 1 339 ? 242.865 206.490 228.566 1.00 139.11 ? 339 ALA B CB  1 
ATOM   8814  N  N   . GLY B 1 340 ? 243.804 209.644 229.486 1.00 132.86 ? 340 GLY B N   1 
ATOM   8815  C  CA  . GLY B 1 340 ? 243.639 211.040 229.128 1.00 129.96 ? 340 GLY B CA  1 
ATOM   8816  C  C   . GLY B 1 340 ? 243.525 211.903 230.363 1.00 128.41 ? 340 GLY B C   1 
ATOM   8817  O  O   . GLY B 1 340 ? 243.486 211.414 231.497 1.00 128.79 ? 340 GLY B O   1 
ATOM   8818  N  N   . ILE B 1 341 ? 243.472 213.209 230.117 1.00 125.94 ? 341 ILE B N   1 
ATOM   8819  C  CA  . ILE B 1 341 ? 243.347 214.216 231.164 1.00 123.61 ? 341 ILE B CA  1 
ATOM   8820  C  C   . ILE B 1 341 ? 242.214 215.159 230.795 1.00 118.36 ? 341 ILE B C   1 
ATOM   8821  O  O   . ILE B 1 341 ? 242.202 215.723 229.696 1.00 118.31 ? 341 ILE B O   1 
ATOM   8822  C  CB  . ILE B 1 341 ? 244.655 215.004 231.364 1.00 127.32 ? 341 ILE B CB  1 
ATOM   8823  C  CG1 . ILE B 1 341 ? 245.826 214.053 231.625 1.00 128.03 ? 341 ILE B CG1 1 
ATOM   8824  C  CG2 . ILE B 1 341 ? 244.507 216.000 232.503 1.00 124.91 ? 341 ILE B CG2 1 
ATOM   8825  C  CD1 . ILE B 1 341 ? 247.152 214.756 231.818 1.00 121.27 ? 341 ILE B CD1 1 
ATOM   8826  N  N   . LEU B 1 342 ? 241.270 215.336 231.714 1.00 115.74 ? 342 LEU B N   1 
ATOM   8827  C  CA  . LEU B 1 342 ? 240.157 216.257 231.540 1.00 115.99 ? 342 LEU B CA  1 
ATOM   8828  C  C   . LEU B 1 342 ? 240.328 217.393 232.533 1.00 116.97 ? 342 LEU B C   1 
ATOM   8829  O  O   . LEU B 1 342 ? 240.454 217.153 233.738 1.00 121.26 ? 342 LEU B O   1 
ATOM   8830  C  CB  . LEU B 1 342 ? 238.817 215.538 231.743 1.00 118.70 ? 342 LEU B CB  1 
ATOM   8831  C  CG  . LEU B 1 342 ? 237.450 216.239 231.737 1.00 117.47 ? 342 LEU B CG  1 
ATOM   8832  C  CD1 . LEU B 1 342 ? 236.363 215.181 231.669 1.00 111.97 ? 342 LEU B CD1 1 
ATOM   8833  C  CD2 . LEU B 1 342 ? 237.196 217.126 232.946 1.00 114.31 ? 342 LEU B CD2 1 
ATOM   8834  N  N   . GLN B 1 343 ? 240.334 218.622 232.035 1.00 116.09 ? 343 GLN B N   1 
ATOM   8835  C  CA  . GLN B 1 343 ? 240.571 219.786 232.871 1.00 120.77 ? 343 GLN B CA  1 
ATOM   8836  C  C   . GLN B 1 343 ? 239.393 220.737 232.769 1.00 120.33 ? 343 GLN B C   1 
ATOM   8837  O  O   . GLN B 1 343 ? 238.860 220.972 231.679 1.00 120.32 ? 343 GLN B O   1 
ATOM   8838  C  CB  . GLN B 1 343 ? 241.861 220.505 232.468 1.00 127.87 ? 343 GLN B CB  1 
ATOM   8839  C  CG  . GLN B 1 343 ? 243.105 219.632 232.528 1.00 131.73 ? 343 GLN B CG  1 
ATOM   8840  C  CD  . GLN B 1 343 ? 244.381 220.444 232.638 1.00 135.07 ? 343 GLN B CD  1 
ATOM   8841  O  OE1 . GLN B 1 343 ? 244.468 221.558 232.121 1.00 132.43 ? 343 GLN B OE1 1 
ATOM   8842  N  NE2 . GLN B 1 343 ? 245.380 219.887 233.313 1.00 135.76 ? 343 GLN B NE2 1 
ATOM   8843  N  N   . ILE B 1 344 ? 238.984 221.277 233.910 1.00 120.75 ? 344 ILE B N   1 
ATOM   8844  C  CA  . ILE B 1 344 ? 237.908 222.251 233.978 1.00 121.42 ? 344 ILE B CA  1 
ATOM   8845  C  C   . ILE B 1 344 ? 238.373 223.434 234.810 1.00 125.95 ? 344 ILE B C   1 
ATOM   8846  O  O   . ILE B 1 344 ? 239.074 223.266 235.814 1.00 127.54 ? 344 ILE B O   1 
ATOM   8847  C  CB  . ILE B 1 344 ? 236.610 221.642 234.553 1.00 121.68 ? 344 ILE B CB  1 
ATOM   8848  C  CG1 . ILE B 1 344 ? 236.840 221.102 235.961 1.00 126.77 ? 344 ILE B CG1 1 
ATOM   8849  C  CG2 . ILE B 1 344 ? 236.068 220.559 233.644 1.00 117.87 ? 344 ILE B CG2 1 
ATOM   8850  C  CD1 . ILE B 1 344 ? 235.593 220.550 236.605 1.00 119.86 ? 344 ILE B CD1 1 
ATOM   8851  N  N   . LYS B 1 345 ? 238.007 224.634 234.370 1.00 129.26 ? 345 LYS B N   1 
ATOM   8852  C  CA  . LYS B 1 345 ? 238.275 225.871 235.091 1.00 132.19 ? 345 LYS B CA  1 
ATOM   8853  C  C   . LYS B 1 345 ? 236.955 226.574 235.365 1.00 128.68 ? 345 LYS B C   1 
ATOM   8854  O  O   . LYS B 1 345 ? 236.172 226.816 234.439 1.00 121.89 ? 345 LYS B O   1 
ATOM   8855  C  CB  . LYS B 1 345 ? 239.211 226.786 234.297 1.00 132.24 ? 345 LYS B CB  1 
ATOM   8856  C  CG  . LYS B 1 345 ? 240.686 226.442 234.432 1.00 134.06 ? 345 LYS B CG  1 
ATOM   8857  C  CD  . LYS B 1 345 ? 241.082 225.299 233.509 1.00 133.78 ? 345 LYS B CD  1 
ATOM   8858  C  CE  . LYS B 1 345 ? 240.643 225.566 232.078 1.00 128.25 ? 345 LYS B CE  1 
ATOM   8859  N  NZ  . LYS B 1 345 ? 240.791 224.360 231.217 1.00 122.03 ? 345 LYS B NZ  1 
ATOM   8860  N  N   . THR B 1 346 ? 236.706 226.895 236.630 1.00 132.02 ? 346 THR B N   1 
ATOM   8861  C  CA  . THR B 1 346 ? 235.455 227.513 237.037 1.00 132.72 ? 346 THR B CA  1 
ATOM   8862  C  C   . THR B 1 346 ? 235.733 228.700 237.946 1.00 140.49 ? 346 THR B C   1 
ATOM   8863  O  O   . THR B 1 346 ? 236.707 228.710 238.704 1.00 143.00 ? 346 THR B O   1 
ATOM   8864  C  CB  . THR B 1 346 ? 234.537 226.520 237.767 1.00 135.11 ? 346 THR B CB  1 
ATOM   8865  O  OG1 . THR B 1 346 ? 235.209 226.004 238.923 1.00 135.57 ? 346 THR B OG1 1 
ATOM   8866  C  CG2 . THR B 1 346 ? 234.153 225.366 236.852 1.00 131.05 ? 346 THR B CG2 1 
ATOM   8867  N  N   . SER B 1 347 ? 234.861 229.700 237.862 1.00 143.59 ? 347 SER B N   1 
ATOM   8868  C  CA  . SER B 1 347 ? 234.963 230.862 238.732 1.00 146.58 ? 347 SER B CA  1 
ATOM   8869  C  C   . SER B 1 347 ? 234.620 230.484 240.168 1.00 143.54 ? 347 SER B C   1 
ATOM   8870  O  O   . SER B 1 347 ? 233.765 229.632 240.425 1.00 141.05 ? 347 SER B O   1 
ATOM   8871  C  CB  . SER B 1 347 ? 234.032 231.975 238.249 1.00 144.50 ? 347 SER B CB  1 
ATOM   8872  O  OG  . SER B 1 347 ? 234.163 232.183 236.854 1.00 141.64 ? 347 SER B OG  1 
ATOM   8873  N  N   . SER B 1 348 ? 235.302 231.129 241.111 1.00 145.45 ? 348 SER B N   1 
ATOM   8874  C  CA  . SER B 1 348 ? 235.057 230.865 242.522 1.00 146.43 ? 348 SER B CA  1 
ATOM   8875  C  C   . SER B 1 348 ? 233.681 231.383 242.923 1.00 148.13 ? 348 SER B C   1 
ATOM   8876  O  O   . SER B 1 348 ? 233.335 232.536 242.650 1.00 145.95 ? 348 SER B O   1 
ATOM   8877  C  CB  . SER B 1 348 ? 236.140 231.516 243.379 1.00 144.51 ? 348 SER B CB  1 
ATOM   8878  O  OG  . SER B 1 348 ? 235.944 231.231 244.753 1.00 140.47 ? 348 SER B OG  1 
ATOM   8879  N  N   . GLY B 1 349 ? 232.895 230.525 243.573 1.00 149.31 ? 349 GLY B N   1 
ATOM   8880  C  CA  . GLY B 1 349 ? 231.570 230.882 244.027 1.00 147.96 ? 349 GLY B CA  1 
ATOM   8881  C  C   . GLY B 1 349 ? 230.467 230.694 243.008 1.00 145.99 ? 349 GLY B C   1 
ATOM   8882  O  O   . GLY B 1 349 ? 229.291 230.862 243.357 1.00 145.18 ? 349 GLY B O   1 
ATOM   8883  N  N   . ALA B 1 350 ? 230.803 230.354 241.762 1.00 144.88 ? 350 ALA B N   1 
ATOM   8884  C  CA  . ALA B 1 350 ? 229.772 230.148 240.751 1.00 140.48 ? 350 ALA B CA  1 
ATOM   8885  C  C   . ALA B 1 350 ? 228.980 228.874 241.019 1.00 138.60 ? 350 ALA B C   1 
ATOM   8886  O  O   . ALA B 1 350 ? 227.749 228.863 240.898 1.00 135.50 ? 350 ALA B O   1 
ATOM   8887  C  CB  . ALA B 1 350 ? 230.401 230.108 239.359 1.00 135.29 ? 350 ALA B CB  1 
ATOM   8888  N  N   . GLU B 1 351 ? 229.666 227.792 241.384 1.00 138.47 ? 351 GLU B N   1 
ATOM   8889  C  CA  . GLU B 1 351 ? 229.022 226.516 241.659 1.00 134.18 ? 351 GLU B CA  1 
ATOM   8890  C  C   . GLU B 1 351 ? 229.625 225.907 242.915 1.00 131.43 ? 351 GLU B C   1 
ATOM   8891  O  O   . GLU B 1 351 ? 230.772 226.190 243.272 1.00 132.78 ? 351 GLU B O   1 
ATOM   8892  C  CB  . GLU B 1 351 ? 229.170 225.539 240.483 1.00 131.31 ? 351 GLU B CB  1 
ATOM   8893  C  CG  . GLU B 1 351 ? 228.559 226.026 239.177 1.00 131.82 ? 351 GLU B CG  1 
ATOM   8894  C  CD  . GLU B 1 351 ? 227.058 225.823 239.123 1.00 132.16 ? 351 GLU B CD  1 
ATOM   8895  O  OE1 . GLU B 1 351 ? 226.520 225.116 240.001 1.00 130.51 ? 351 GLU B OE1 1 
ATOM   8896  O  OE2 . GLU B 1 351 ? 226.415 226.370 238.202 1.00 132.19 ? 351 GLU B OE2 1 
ATOM   8897  N  N   . THR B 1 352 ? 228.838 225.068 243.583 1.00 127.18 ? 352 THR B N   1 
ATOM   8898  C  CA  . THR B 1 352 ? 229.322 224.360 244.759 1.00 124.48 ? 352 THR B CA  1 
ATOM   8899  C  C   . THR B 1 352 ? 230.406 223.361 244.369 1.00 127.36 ? 352 THR B C   1 
ATOM   8900  O  O   . THR B 1 352 ? 230.391 222.788 243.276 1.00 130.26 ? 352 THR B O   1 
ATOM   8901  C  CB  . THR B 1 352 ? 228.172 223.640 245.459 1.00 121.98 ? 352 THR B CB  1 
ATOM   8902  O  OG1 . THR B 1 352 ? 227.738 222.537 244.657 1.00 120.61 ? 352 THR B OG1 1 
ATOM   8903  C  CG2 . THR B 1 352 ? 227.006 224.589 245.663 1.00 122.11 ? 352 THR B CG2 1 
ATOM   8904  N  N   . SER B 1 353 ? 231.361 223.161 245.280 1.00 125.12 ? 353 SER B N   1 
ATOM   8905  C  CA  . SER B 1 353 ? 232.520 222.329 244.968 1.00 125.60 ? 353 SER B CA  1 
ATOM   8906  C  C   . SER B 1 353 ? 232.126 220.876 244.729 1.00 125.67 ? 353 SER B C   1 
ATOM   8907  O  O   . SER B 1 353 ? 232.636 220.234 243.803 1.00 124.65 ? 353 SER B O   1 
ATOM   8908  C  CB  . SER B 1 353 ? 233.552 222.423 246.090 1.00 128.66 ? 353 SER B CB  1 
ATOM   8909  O  OG  . SER B 1 353 ? 234.636 221.542 245.854 1.00 132.91 ? 353 SER B OG  1 
ATOM   8910  N  N   . ALA B 1 354 ? 231.228 220.337 245.558 1.00 125.74 ? 354 ALA B N   1 
ATOM   8911  C  CA  . ALA B 1 354 ? 230.857 218.929 245.436 1.00 122.85 ? 354 ALA B CA  1 
ATOM   8912  C  C   . ALA B 1 354 ? 230.199 218.644 244.093 1.00 118.71 ? 354 ALA B C   1 
ATOM   8913  O  O   . ALA B 1 354 ? 230.463 217.610 243.469 1.00 112.95 ? 354 ALA B O   1 
ATOM   8914  C  CB  . ALA B 1 354 ? 229.932 218.529 246.585 1.00 119.03 ? 354 ALA B CB  1 
ATOM   8915  N  N   . PHE B 1 355 ? 229.337 219.551 243.635 1.00 117.93 ? 355 PHE B N   1 
ATOM   8916  C  CA  . PHE B 1 355 ? 228.724 219.403 242.322 1.00 106.04 ? 355 PHE B CA  1 
ATOM   8917  C  C   . PHE B 1 355 ? 229.774 219.404 241.224 1.00 103.55 ? 355 PHE B C   1 
ATOM   8918  O  O   . PHE B 1 355 ? 229.698 218.610 240.279 1.00 105.26 ? 355 PHE B O   1 
ATOM   8919  C  CB  . PHE B 1 355 ? 227.705 220.518 242.114 1.00 101.25 ? 355 PHE B CB  1 
ATOM   8920  C  CG  . PHE B 1 355 ? 226.838 220.329 240.923 1.00 100.12 ? 355 PHE B CG  1 
ATOM   8921  C  CD1 . PHE B 1 355 ? 226.142 219.153 240.738 1.00 101.37 ? 355 PHE B CD1 1 
ATOM   8922  C  CD2 . PHE B 1 355 ? 226.677 221.347 240.009 1.00 102.57 ? 355 PHE B CD2 1 
ATOM   8923  C  CE1 . PHE B 1 355 ? 225.338 218.977 239.634 1.00 102.24 ? 355 PHE B CE1 1 
ATOM   8924  C  CE2 . PHE B 1 355 ? 225.867 221.186 238.910 1.00 102.74 ? 355 PHE B CE2 1 
ATOM   8925  C  CZ  . PHE B 1 355 ? 225.193 219.999 238.721 1.00 100.75 ? 355 PHE B CZ  1 
ATOM   8926  N  N   . ILE B 1 356 ? 230.776 220.271 241.346 1.00 105.70 ? 356 ILE B N   1 
ATOM   8927  C  CA  . ILE B 1 356 ? 231.839 220.330 240.349 1.00 109.95 ? 356 ILE B CA  1 
ATOM   8928  C  C   . ILE B 1 356 ? 232.617 219.019 240.315 1.00 109.41 ? 356 ILE B C   1 
ATOM   8929  O  O   . ILE B 1 356 ? 232.892 218.471 239.242 1.00 110.67 ? 356 ILE B O   1 
ATOM   8930  C  CB  . ILE B 1 356 ? 232.757 221.533 240.624 1.00 117.85 ? 356 ILE B CB  1 
ATOM   8931  C  CG1 . ILE B 1 356 ? 232.041 222.835 240.259 1.00 120.09 ? 356 ILE B CG1 1 
ATOM   8932  C  CG2 . ILE B 1 356 ? 234.060 221.401 239.854 1.00 122.23 ? 356 ILE B CG2 1 
ATOM   8933  C  CD1 . ILE B 1 356 ? 232.656 224.065 240.886 1.00 123.46 ? 356 ILE B CD1 1 
ATOM   8934  N  N   . GLU B 1 357 ? 232.980 218.493 241.487 1.00 108.44 ? 357 GLU B N   1 
ATOM   8935  C  CA  . GLU B 1 357 ? 233.732 217.241 241.522 1.00 103.42 ? 357 GLU B CA  1 
ATOM   8936  C  C   . GLU B 1 357 ? 232.908 216.077 240.993 1.00 102.09 ? 357 GLU B C   1 
ATOM   8937  O  O   . GLU B 1 357 ? 233.435 215.200 240.295 1.00 101.91 ? 357 GLU B O   1 
ATOM   8938  C  CB  . GLU B 1 357 ? 234.219 216.947 242.938 1.00 108.36 ? 357 GLU B CB  1 
ATOM   8939  C  CG  . GLU B 1 357 ? 234.863 218.127 243.640 1.00 117.45 ? 357 GLU B CG  1 
ATOM   8940  C  CD  . GLU B 1 357 ? 236.004 218.732 242.844 1.00 124.39 ? 357 GLU B CD  1 
ATOM   8941  O  OE1 . GLU B 1 357 ? 236.786 217.966 242.242 1.00 123.69 ? 357 GLU B OE1 1 
ATOM   8942  O  OE2 . GLU B 1 357 ? 236.120 219.975 242.823 1.00 127.50 ? 357 GLU B OE2 1 
ATOM   8943  N  N   . ARG B 1 358 ? 231.615 216.043 241.317 1.00 106.08 ? 358 ARG B N   1 
ATOM   8944  C  CA  . ARG B 1 358 ? 230.753 214.993 240.788 1.00 107.46 ? 358 ARG B CA  1 
ATOM   8945  C  C   . ARG B 1 358 ? 230.710 215.045 239.269 1.00 98.71  ? 358 ARG B C   1 
ATOM   8946  O  O   . ARG B 1 358 ? 230.907 214.025 238.598 1.00 94.91  ? 358 ARG B O   1 
ATOM   8947  C  CB  . ARG B 1 358 ? 229.343 215.122 241.364 1.00 110.11 ? 358 ARG B CB  1 
ATOM   8948  C  CG  . ARG B 1 358 ? 229.064 214.231 242.560 1.00 107.57 ? 358 ARG B CG  1 
ATOM   8949  C  CD  . ARG B 1 358 ? 227.594 214.291 242.942 1.00 110.70 ? 358 ARG B CD  1 
ATOM   8950  N  NE  . ARG B 1 358 ? 227.243 215.568 243.553 1.00 112.85 ? 358 ARG B NE  1 
ATOM   8951  C  CZ  . ARG B 1 358 ? 226.009 216.047 243.630 1.00 112.78 ? 358 ARG B CZ  1 
ATOM   8952  N  NH1 . ARG B 1 358 ? 224.978 215.383 243.134 1.00 112.62 ? 358 ARG B NH1 1 
ATOM   8953  N  NH2 . ARG B 1 358 ? 225.805 217.222 244.217 1.00 108.07 ? 358 ARG B NH2 1 
ATOM   8954  N  N   . VAL B 1 359 ? 230.449 216.231 238.712 1.00 93.44  ? 359 VAL B N   1 
ATOM   8955  C  CA  . VAL B 1 359 ? 230.419 216.376 237.261 1.00 81.46  ? 359 VAL B CA  1 
ATOM   8956  C  C   . VAL B 1 359 ? 231.743 215.930 236.670 1.00 83.74  ? 359 VAL B C   1 
ATOM   8957  O  O   . VAL B 1 359 ? 231.785 215.218 235.659 1.00 86.54  ? 359 VAL B O   1 
ATOM   8958  C  CB  . VAL B 1 359 ? 230.088 217.827 236.874 1.00 78.92  ? 359 VAL B CB  1 
ATOM   8959  C  CG1 . VAL B 1 359 ? 230.204 218.010 235.379 1.00 82.14  ? 359 VAL B CG1 1 
ATOM   8960  C  CG2 . VAL B 1 359 ? 228.711 218.192 237.329 1.00 81.00  ? 359 VAL B CG2 1 
ATOM   8961  N  N   . ALA B 1 360 ? 232.843 216.317 237.308 1.00 89.41  ? 360 ALA B N   1 
ATOM   8962  C  CA  . ALA B 1 360 ? 234.155 215.975 236.785 1.00 94.39  ? 360 ALA B CA  1 
ATOM   8963  C  C   . ALA B 1 360 ? 234.331 214.469 236.706 1.00 99.23  ? 360 ALA B C   1 
ATOM   8964  O  O   . ALA B 1 360 ? 234.739 213.937 235.669 1.00 104.51 ? 360 ALA B O   1 
ATOM   8965  C  CB  . ALA B 1 360 ? 235.246 216.603 237.650 1.00 97.60  ? 360 ALA B CB  1 
ATOM   8966  N  N   . ASP B 1 361 ? 233.994 213.755 237.779 1.00 96.45  ? 361 ASP B N   1 
ATOM   8967  C  CA  . ASP B 1 361 ? 234.285 212.326 237.757 1.00 95.09  ? 361 ASP B CA  1 
ATOM   8968  C  C   . ASP B 1 361 ? 233.321 211.561 236.860 1.00 92.33  ? 361 ASP B C   1 
ATOM   8969  O  O   . ASP B 1 361 ? 233.746 210.626 236.169 1.00 90.41  ? 361 ASP B O   1 
ATOM   8970  C  CB  . ASP B 1 361 ? 234.296 211.738 239.172 1.00 97.25  ? 361 ASP B CB  1 
ATOM   8971  C  CG  . ASP B 1 361 ? 232.924 211.354 239.665 1.00 102.07 ? 361 ASP B CG  1 
ATOM   8972  O  OD1 . ASP B 1 361 ? 232.154 212.250 240.050 1.00 103.72 ? 361 ASP B OD1 1 
ATOM   8973  O  OD2 . ASP B 1 361 ? 232.616 210.144 239.674 1.00 101.05 ? 361 ASP B OD2 1 
ATOM   8974  N  N   . ILE B 1 362 ? 232.041 211.944 236.820 1.00 92.01  ? 362 ILE B N   1 
ATOM   8975  C  CA  . ILE B 1 362 ? 231.114 211.226 235.949 1.00 89.56  ? 362 ILE B CA  1 
ATOM   8976  C  C   . ILE B 1 362 ? 231.487 211.455 234.492 1.00 90.08  ? 362 ILE B C   1 
ATOM   8977  O  O   . ILE B 1 362 ? 231.487 210.519 233.679 1.00 92.87  ? 362 ILE B O   1 
ATOM   8978  C  CB  . ILE B 1 362 ? 229.654 211.627 236.226 1.00 86.25  ? 362 ILE B CB  1 
ATOM   8979  C  CG1 . ILE B 1 362 ? 228.742 211.113 235.128 1.00 77.48  ? 362 ILE B CG1 1 
ATOM   8980  C  CG2 . ILE B 1 362 ? 229.481 213.113 236.203 1.00 90.90  ? 362 ILE B CG2 1 
ATOM   8981  C  CD1 . ILE B 1 362 ? 227.309 211.468 235.365 1.00 75.91  ? 362 ILE B CD1 1 
ATOM   8982  N  N   . SER B 1 363 ? 231.828 212.697 234.137 1.00 89.80  ? 363 SER B N   1 
ATOM   8983  C  CA  . SER B 1 363 ? 232.258 212.964 232.777 1.00 87.74  ? 363 SER B CA  1 
ATOM   8984  C  C   . SER B 1 363 ? 233.580 212.281 232.465 1.00 92.87  ? 363 SER B C   1 
ATOM   8985  O  O   . SER B 1 363 ? 233.811 211.893 231.318 1.00 98.04  ? 363 SER B O   1 
ATOM   8986  C  CB  . SER B 1 363 ? 232.350 214.465 232.549 1.00 83.98  ? 363 SER B CB  1 
ATOM   8987  O  OG  . SER B 1 363 ? 231.075 215.057 232.677 1.00 78.32  ? 363 SER B OG  1 
ATOM   8988  N  N   . GLN B 1 364 ? 234.458 212.119 233.455 1.00 92.90  ? 364 GLN B N   1 
ATOM   8989  C  CA  . GLN B 1 364 ? 235.695 211.387 233.213 1.00 96.63  ? 364 GLN B CA  1 
ATOM   8990  C  C   . GLN B 1 364 ? 235.394 209.935 232.882 1.00 98.40  ? 364 GLN B C   1 
ATOM   8991  O  O   . GLN B 1 364 ? 235.984 209.353 231.963 1.00 100.77 ? 364 GLN B O   1 
ATOM   8992  C  CB  . GLN B 1 364 ? 236.615 211.492 234.432 1.00 98.20  ? 364 GLN B CB  1 
ATOM   8993  C  CG  . GLN B 1 364 ? 237.886 210.645 234.365 1.00 106.27 ? 364 GLN B CG  1 
ATOM   8994  C  CD  . GLN B 1 364 ? 237.659 209.182 234.682 1.00 108.34 ? 364 GLN B CD  1 
ATOM   8995  O  OE1 . GLN B 1 364 ? 238.303 208.306 234.108 1.00 116.95 ? 364 GLN B OE1 1 
ATOM   8996  N  NE2 . GLN B 1 364 ? 236.737 208.911 235.595 1.00 99.49  ? 364 GLN B NE2 1 
ATOM   8997  N  N   . HIS B 1 365 ? 234.478 209.331 233.637 1.00 98.21  ? 365 HIS B N   1 
ATOM   8998  C  CA  . HIS B 1 365 ? 234.086 207.958 233.350 1.00 101.11 ? 365 HIS B CA  1 
ATOM   8999  C  C   . HIS B 1 365 ? 233.492 207.846 231.956 1.00 99.70  ? 365 HIS B C   1 
ATOM   9000  O  O   . HIS B 1 365 ? 233.794 206.902 231.215 1.00 101.54 ? 365 HIS B O   1 
ATOM   9001  C  CB  . HIS B 1 365 ? 233.091 207.458 234.396 1.00 100.25 ? 365 HIS B CB  1 
ATOM   9002  C  CG  . HIS B 1 365 ? 232.909 205.972 234.390 1.00 99.40  ? 365 HIS B CG  1 
ATOM   9003  N  ND1 . HIS B 1 365 ? 233.622 205.139 233.556 1.00 99.66  ? 365 HIS B ND1 1 
ATOM   9004  C  CD2 . HIS B 1 365 ? 232.087 205.172 235.107 1.00 95.92  ? 365 HIS B CD2 1 
ATOM   9005  C  CE1 . HIS B 1 365 ? 233.251 203.889 233.762 1.00 95.76  ? 365 HIS B CE1 1 
ATOM   9006  N  NE2 . HIS B 1 365 ? 232.321 203.881 234.700 1.00 94.10  ? 365 HIS B NE2 1 
ATOM   9007  N  N   . MET B 1 366 ? 232.652 208.805 231.572 1.00 95.52  ? 366 MET B N   1 
ATOM   9008  C  CA  . MET B 1 366 ? 232.044 208.711 230.255 1.00 92.74  ? 366 MET B CA  1 
ATOM   9009  C  C   . MET B 1 366 ? 233.062 208.959 229.156 1.00 96.53  ? 366 MET B C   1 
ATOM   9010  O  O   . MET B 1 366 ? 232.955 208.387 228.070 1.00 98.49  ? 366 MET B O   1 
ATOM   9011  C  CB  . MET B 1 366 ? 230.871 209.668 230.132 1.00 90.49  ? 366 MET B CB  1 
ATOM   9012  C  CG  . MET B 1 366 ? 229.807 209.409 231.148 1.00 93.89  ? 366 MET B CG  1 
ATOM   9013  S  SD  . MET B 1 366 ? 228.760 208.067 230.580 1.00 110.94 ? 366 MET B SD  1 
ATOM   9014  C  CE  . MET B 1 366 ? 228.615 208.471 228.847 1.00 96.10  ? 366 MET B CE  1 
ATOM   9015  N  N   . ALA B 1 367 ? 234.062 209.799 229.415 1.00 100.68 ? 367 ALA B N   1 
ATOM   9016  C  CA  . ALA B 1 367 ? 235.139 209.976 228.448 1.00 106.80 ? 367 ALA B CA  1 
ATOM   9017  C  C   . ALA B 1 367 ? 235.938 208.690 228.283 1.00 108.45 ? 367 ALA B C   1 
ATOM   9018  O  O   . ALA B 1 367 ? 236.329 208.329 227.167 1.00 108.34 ? 367 ALA B O   1 
ATOM   9019  C  CB  . ALA B 1 367 ? 236.047 211.128 228.876 1.00 106.63 ? 367 ALA B CB  1 
ATOM   9020  N  N   . ALA B 1 368 ? 236.195 207.988 229.386 1.00 107.50 ? 368 ALA B N   1 
ATOM   9021  C  CA  . ALA B 1 368 ? 236.872 206.699 229.289 1.00 108.83 ? 368 ALA B CA  1 
ATOM   9022  C  C   . ALA B 1 368 ? 236.039 205.711 228.487 1.00 108.21 ? 368 ALA B C   1 
ATOM   9023  O  O   . ALA B 1 368 ? 236.570 204.962 227.657 1.00 111.88 ? 368 ALA B O   1 
ATOM   9024  C  CB  . ALA B 1 368 ? 237.162 206.148 230.685 1.00 111.13 ? 368 ALA B CB  1 
ATOM   9025  N  N   . LEU B 1 369 ? 234.727 205.701 228.718 1.00 104.91 ? 369 LEU B N   1 
ATOM   9026  C  CA  . LEU B 1 369 ? 233.850 204.821 227.954 1.00 105.97 ? 369 LEU B CA  1 
ATOM   9027  C  C   . LEU B 1 369 ? 233.846 205.198 226.478 1.00 109.93 ? 369 LEU B C   1 
ATOM   9028  O  O   . LEU B 1 369 ? 233.802 204.325 225.603 1.00 111.92 ? 369 LEU B O   1 
ATOM   9029  C  CB  . LEU B 1 369 ? 232.439 204.871 228.532 1.00 102.64 ? 369 LEU B CB  1 
ATOM   9030  C  CG  . LEU B 1 369 ? 232.294 204.274 229.933 1.00 101.82 ? 369 LEU B CG  1 
ATOM   9031  C  CD1 . LEU B 1 369 ? 230.963 204.662 230.560 1.00 96.02  ? 369 LEU B CD1 1 
ATOM   9032  C  CD2 . LEU B 1 369 ? 232.453 202.762 229.889 1.00 98.42  ? 369 LEU B CD2 1 
ATOM   9033  N  N   . ALA B 1 370 ? 233.885 206.497 226.186 1.00 108.91 ? 370 ALA B N   1 
ATOM   9034  C  CA  . ALA B 1 370 ? 233.954 206.951 224.805 1.00 107.67 ? 370 ALA B CA  1 
ATOM   9035  C  C   . ALA B 1 370 ? 235.247 206.502 224.152 1.00 108.05 ? 370 ALA B C   1 
ATOM   9036  O  O   . ALA B 1 370 ? 235.256 206.117 222.981 1.00 107.93 ? 370 ALA B O   1 
ATOM   9037  C  CB  . ALA B 1 370 ? 233.821 208.471 224.744 1.00 104.50 ? 370 ALA B CB  1 
ATOM   9038  N  N   . LEU B 1 371 ? 236.354 206.556 224.891 1.00 108.74 ? 371 LEU B N   1 
ATOM   9039  C  CA  . LEU B 1 371 ? 237.616 206.051 224.358 1.00 111.14 ? 371 LEU B CA  1 
ATOM   9040  C  C   . LEU B 1 371 ? 237.529 204.556 224.086 1.00 110.93 ? 371 LEU B C   1 
ATOM   9041  O  O   . LEU B 1 371 ? 238.063 204.061 223.084 1.00 110.91 ? 371 LEU B O   1 
ATOM   9042  C  CB  . LEU B 1 371 ? 238.757 206.353 225.329 1.00 114.49 ? 371 LEU B CB  1 
ATOM   9043  C  CG  . LEU B 1 371 ? 239.201 207.813 225.429 1.00 117.47 ? 371 LEU B CG  1 
ATOM   9044  C  CD1 . LEU B 1 371 ? 240.162 208.006 226.590 1.00 120.05 ? 371 LEU B CD1 1 
ATOM   9045  C  CD2 . LEU B 1 371 ? 239.839 208.262 224.126 1.00 119.70 ? 371 LEU B CD2 1 
ATOM   9046  N  N   . GLU B 1 372 ? 236.880 203.819 224.988 1.00 113.36 ? 372 GLU B N   1 
ATOM   9047  C  CA  . GLU B 1 372 ? 236.676 202.391 224.773 1.00 117.93 ? 372 GLU B CA  1 
ATOM   9048  C  C   . GLU B 1 372 ? 235.904 202.147 223.486 1.00 117.88 ? 372 GLU B C   1 
ATOM   9049  O  O   . GLU B 1 372 ? 236.292 201.313 222.661 1.00 119.11 ? 372 GLU B O   1 
ATOM   9050  C  CB  . GLU B 1 372 ? 235.945 201.783 225.970 1.00 119.46 ? 372 GLU B CB  1 
ATOM   9051  C  CG  . GLU B 1 372 ? 235.551 200.328 225.787 1.00 123.90 ? 372 GLU B CG  1 
ATOM   9052  C  CD  . GLU B 1 372 ? 234.807 199.773 226.985 1.00 125.44 ? 372 GLU B CD  1 
ATOM   9053  O  OE1 . GLU B 1 372 ? 235.426 199.644 228.062 1.00 130.12 ? 372 GLU B OE1 1 
ATOM   9054  O  OE2 . GLU B 1 372 ? 233.603 199.468 226.851 1.00 124.37 ? 372 GLU B OE2 1 
ATOM   9055  N  N   . GLN B 1 373 ? 234.820 202.895 223.286 1.00 116.65 ? 373 GLN B N   1 
ATOM   9056  C  CA  . GLN B 1 373 ? 234.041 202.768 222.058 1.00 116.28 ? 373 GLN B CA  1 
ATOM   9057  C  C   . GLN B 1 373 ? 234.877 203.138 220.840 1.00 115.92 ? 373 GLN B C   1 
ATOM   9058  O  O   . GLN B 1 373 ? 234.785 202.491 219.789 1.00 115.91 ? 373 GLN B O   1 
ATOM   9059  C  CB  . GLN B 1 373 ? 232.792 203.648 222.145 1.00 112.94 ? 373 GLN B CB  1 
ATOM   9060  C  CG  . GLN B 1 373 ? 231.809 203.488 220.997 1.00 108.69 ? 373 GLN B CG  1 
ATOM   9061  C  CD  . GLN B 1 373 ? 230.872 204.677 220.870 1.00 105.80 ? 373 GLN B CD  1 
ATOM   9062  O  OE1 . GLN B 1 373 ? 231.257 205.813 221.143 1.00 104.84 ? 373 GLN B OE1 1 
ATOM   9063  N  NE2 . GLN B 1 373 ? 229.635 204.419 220.460 1.00 101.32 ? 373 GLN B NE2 1 
ATOM   9064  N  N   . GLU B 1 374 ? 235.709 204.172 220.970 1.00 114.92 ? 374 GLU B N   1 
ATOM   9065  C  CA  . GLU B 1 374 ? 236.504 204.647 219.845 1.00 117.75 ? 374 GLU B CA  1 
ATOM   9066  C  C   . GLU B 1 374 ? 237.502 203.593 219.394 1.00 118.73 ? 374 GLU B C   1 
ATOM   9067  O  O   . GLU B 1 374 ? 237.578 203.268 218.204 1.00 119.77 ? 374 GLU B O   1 
ATOM   9068  C  CB  . GLU B 1 374 ? 237.223 205.942 220.224 1.00 118.48 ? 374 GLU B CB  1 
ATOM   9069  C  CG  . GLU B 1 374 ? 238.114 206.507 219.127 1.00 121.32 ? 374 GLU B CG  1 
ATOM   9070  C  CD  . GLU B 1 374 ? 237.326 207.021 217.937 1.00 122.15 ? 374 GLU B CD  1 
ATOM   9071  O  OE1 . GLU B 1 374 ? 236.150 207.400 218.117 1.00 120.37 ? 374 GLU B OE1 1 
ATOM   9072  O  OE2 . GLU B 1 374 ? 237.885 207.046 216.821 1.00 123.96 ? 374 GLU B OE2 1 
ATOM   9073  N  N   . LYS B 1 375 ? 238.275 203.036 220.326 1.00 117.59 ? 375 LYS B N   1 
ATOM   9074  C  CA  . LYS B 1 375 ? 239.214 202.010 219.888 1.00 119.13 ? 375 LYS B CA  1 
ATOM   9075  C  C   . LYS B 1 375 ? 238.554 200.651 219.705 1.00 122.68 ? 375 LYS B C   1 
ATOM   9076  O  O   . LYS B 1 375 ? 239.212 199.728 219.213 1.00 123.00 ? 375 LYS B O   1 
ATOM   9077  C  CB  . LYS B 1 375 ? 240.414 201.878 220.832 1.00 117.76 ? 375 LYS B CB  1 
ATOM   9078  C  CG  . LYS B 1 375 ? 240.725 203.075 221.708 1.00 116.22 ? 375 LYS B CG  1 
ATOM   9079  C  CD  . LYS B 1 375 ? 241.658 202.657 222.843 1.00 114.22 ? 375 LYS B CD  1 
ATOM   9080  C  CE  . LYS B 1 375 ? 240.953 201.906 223.952 1.00 116.48 ? 375 LYS B CE  1 
ATOM   9081  N  NZ  . LYS B 1 375 ? 239.820 202.679 224.496 1.00 117.62 ? 375 LYS B NZ  1 
ATOM   9082  N  N   . SER B 1 376 ? 237.282 200.501 220.080 1.00 124.31 ? 376 SER B N   1 
ATOM   9083  C  CA  . SER B 1 376 ? 236.533 199.327 219.651 1.00 125.22 ? 376 SER B CA  1 
ATOM   9084  C  C   . SER B 1 376 ? 236.146 199.441 218.183 1.00 125.76 ? 376 SER B C   1 
ATOM   9085  O  O   . SER B 1 376 ? 236.202 198.455 217.440 1.00 125.79 ? 376 SER B O   1 
ATOM   9086  C  CB  . SER B 1 376 ? 235.291 199.145 220.523 1.00 125.47 ? 376 SER B CB  1 
ATOM   9087  O  OG  . SER B 1 376 ? 235.636 199.071 221.895 1.00 126.17 ? 376 SER B OG  1 
ATOM   9088  N  N   . ARG B 1 377 ? 235.745 200.640 217.752 1.00 126.79 ? 377 ARG B N   1 
ATOM   9089  C  CA  . ARG B 1 377 ? 235.478 200.867 216.336 1.00 130.00 ? 377 ARG B CA  1 
ATOM   9090  C  C   . ARG B 1 377 ? 236.746 200.715 215.507 1.00 131.08 ? 377 ARG B C   1 
ATOM   9091  O  O   . ARG B 1 377 ? 236.717 200.144 214.410 1.00 132.16 ? 377 ARG B O   1 
ATOM   9092  C  CB  . ARG B 1 377 ? 234.865 202.252 216.133 1.00 127.11 ? 377 ARG B CB  1 
ATOM   9093  C  CG  . ARG B 1 377 ? 234.330 202.498 214.732 1.00 126.93 ? 377 ARG B CG  1 
ATOM   9094  C  CD  . ARG B 1 377 ? 233.867 203.937 214.566 1.00 123.72 ? 377 ARG B CD  1 
ATOM   9095  N  NE  . ARG B 1 377 ? 234.984 204.875 214.572 1.00 123.58 ? 377 ARG B NE  1 
ATOM   9096  C  CZ  . ARG B 1 377 ? 235.723 205.170 213.510 1.00 125.71 ? 377 ARG B CZ  1 
ATOM   9097  N  NH1 . ARG B 1 377 ? 235.489 204.618 212.331 1.00 128.55 ? 377 ARG B NH1 1 
ATOM   9098  N  NH2 . ARG B 1 377 ? 236.720 206.040 213.636 1.00 123.94 ? 377 ARG B NH2 1 
ATOM   9099  N  N   . GLN B 1 378 ? 237.868 201.217 216.013 1.00 128.69 ? 378 GLN B N   1 
ATOM   9100  C  CA  . GLN B 1 378 ? 239.141 201.121 215.309 1.00 128.33 ? 378 GLN B CA  1 
ATOM   9101  C  C   . GLN B 1 378 ? 239.739 199.725 215.446 1.00 127.71 ? 378 GLN B C   1 
ATOM   9102  O  O   . GLN B 1 378 ? 240.110 199.099 214.453 1.00 131.64 ? 378 GLN B O   1 
ATOM   9103  C  CB  . GLN B 1 378 ? 240.123 202.169 215.834 1.00 129.97 ? 378 GLN B CB  1 
ATOM   9104  C  CG  . GLN B 1 378 ? 239.738 203.601 215.500 1.00 133.54 ? 378 GLN B CG  1 
ATOM   9105  C  CD  . GLN B 1 378 ? 240.850 204.588 215.795 1.00 137.97 ? 378 GLN B CD  1 
ATOM   9106  O  OE1 . GLN B 1 378 ? 242.025 204.223 215.841 1.00 141.82 ? 378 GLN B OE1 1 
ATOM   9107  N  NE2 . GLN B 1 378 ? 240.483 205.848 215.998 1.00 135.67 ? 378 GLN B NE2 1 
ATOM   9108  N  N   . ILE B 1 384 ? 229.497 200.625 202.064 1.00 56.06  ? 384 ILE B N   1 
ATOM   9109  C  CA  . ILE B 1 384 ? 230.705 200.165 201.402 1.00 58.25  ? 384 ILE B CA  1 
ATOM   9110  C  C   . ILE B 1 384 ? 231.167 201.201 200.386 1.00 66.44  ? 384 ILE B C   1 
ATOM   9111  O  O   . ILE B 1 384 ? 232.277 201.719 200.477 1.00 69.06  ? 384 ILE B O   1 
ATOM   9112  C  CB  . ILE B 1 384 ? 230.485 198.806 200.735 1.00 62.17  ? 384 ILE B CB  1 
ATOM   9113  C  CG1 . ILE B 1 384 ? 230.426 197.693 201.783 1.00 68.96  ? 384 ILE B CG1 1 
ATOM   9114  C  CG2 . ILE B 1 384 ? 231.601 198.515 199.742 1.00 62.12  ? 384 ILE B CG2 1 
ATOM   9115  C  CD1 . ILE B 1 384 ? 231.303 197.931 202.995 1.00 66.69  ? 384 ILE B CD1 1 
ATOM   9116  N  N   . GLN B 1 385 ? 230.310 201.491 199.407 1.00 68.30  ? 385 GLN B N   1 
ATOM   9117  C  CA  . GLN B 1 385 ? 230.634 202.429 198.339 1.00 61.76  ? 385 GLN B CA  1 
ATOM   9118  C  C   . GLN B 1 385 ? 229.456 203.371 198.099 1.00 60.07  ? 385 GLN B C   1 
ATOM   9119  O  O   . GLN B 1 385 ? 229.640 204.503 197.642 1.00 61.65  ? 385 GLN B O   1 
ATOM   9120  C  CB  . GLN B 1 385 ? 231.091 201.611 197.112 1.00 60.38  ? 385 GLN B CB  1 
ATOM   9121  C  CG  . GLN B 1 385 ? 231.692 202.241 195.838 1.00 65.63  ? 385 GLN B CG  1 
ATOM   9122  C  CD  . GLN B 1 385 ? 230.918 203.343 195.163 1.00 73.80  ? 385 GLN B CD  1 
ATOM   9123  O  OE1 . GLN B 1 385 ? 229.715 203.495 195.345 1.00 71.21  ? 385 GLN B OE1 1 
ATOM   9124  N  NE2 . GLN B 1 385 ? 231.614 204.101 194.328 1.00 77.51  ? 385 GLN B NE2 1 
ATOM   9125  N  N   . PHE B 1 386 ? 228.260 202.957 198.510 1.00 60.22  ? 386 PHE B N   1 
ATOM   9126  C  CA  . PHE B 1 386 ? 227.061 203.774 198.435 1.00 57.72  ? 386 PHE B CA  1 
ATOM   9127  C  C   . PHE B 1 386 ? 226.536 203.960 199.848 1.00 56.36  ? 386 PHE B C   1 
ATOM   9128  O  O   . PHE B 1 386 ? 226.898 203.210 200.756 1.00 57.05  ? 386 PHE B O   1 
ATOM   9129  C  CB  . PHE B 1 386 ? 225.999 203.121 197.554 1.00 59.60  ? 386 PHE B CB  1 
ATOM   9130  C  CG  . PHE B 1 386 ? 225.897 203.708 196.174 1.00 62.36  ? 386 PHE B CG  1 
ATOM   9131  C  CD1 . PHE B 1 386 ? 225.182 204.866 195.948 1.00 63.21  ? 386 PHE B CD1 1 
ATOM   9132  C  CD2 . PHE B 1 386 ? 226.525 203.098 195.107 1.00 63.30  ? 386 PHE B CD2 1 
ATOM   9133  C  CE1 . PHE B 1 386 ? 225.086 205.401 194.678 1.00 60.41  ? 386 PHE B CE1 1 
ATOM   9134  C  CE2 . PHE B 1 386 ? 226.437 203.630 193.841 1.00 63.25  ? 386 PHE B CE2 1 
ATOM   9135  C  CZ  . PHE B 1 386 ? 225.718 204.783 193.625 1.00 58.96  ? 386 PHE B CZ  1 
ATOM   9136  N  N   . ASP B 1 387 ? 225.692 204.971 200.029 1.00 60.44  ? 387 ASP B N   1 
ATOM   9137  C  CA  . ASP B 1 387 ? 225.177 205.315 201.350 1.00 63.76  ? 387 ASP B CA  1 
ATOM   9138  C  C   . ASP B 1 387 ? 223.909 204.533 201.652 1.00 63.33  ? 387 ASP B C   1 
ATOM   9139  O  O   . ASP B 1 387 ? 222.964 204.580 200.854 1.00 66.36  ? 387 ASP B O   1 
ATOM   9140  C  CB  . ASP B 1 387 ? 224.887 206.799 201.440 1.00 66.12  ? 387 ASP B CB  1 
ATOM   9141  C  CG  . ASP B 1 387 ? 223.979 207.142 202.588 1.00 69.84  ? 387 ASP B CG  1 
ATOM   9142  O  OD1 . ASP B 1 387 ? 224.253 206.684 203.714 1.00 73.68  ? 387 ASP B OD1 1 
ATOM   9143  O  OD2 . ASP B 1 387 ? 222.988 207.861 202.363 1.00 69.24  ? 387 ASP B OD2 1 
ATOM   9144  N  N   . PRO B 1 388 ? 223.833 203.821 202.777 1.00 61.66  ? 388 PRO B N   1 
ATOM   9145  C  CA  . PRO B 1 388 ? 222.602 203.114 203.138 1.00 62.08  ? 388 PRO B CA  1 
ATOM   9146  C  C   . PRO B 1 388 ? 221.533 203.981 203.783 1.00 59.96  ? 388 PRO B C   1 
ATOM   9147  O  O   . PRO B 1 388 ? 220.549 203.436 204.286 1.00 61.99  ? 388 PRO B O   1 
ATOM   9148  C  CB  . PRO B 1 388 ? 223.107 202.054 204.123 1.00 59.55  ? 388 PRO B CB  1 
ATOM   9149  C  CG  . PRO B 1 388 ? 224.284 202.656 204.742 1.00 55.62  ? 388 PRO B CG  1 
ATOM   9150  C  CD  . PRO B 1 388 ? 224.935 203.513 203.701 1.00 58.47  ? 388 PRO B CD  1 
ATOM   9151  N  N   . MET B 1 389 ? 221.688 205.299 203.777 1.00 60.72  ? 389 MET B N   1 
ATOM   9152  C  CA  . MET B 1 389 ? 220.738 206.229 204.375 1.00 70.14  ? 389 MET B CA  1 
ATOM   9153  C  C   . MET B 1 389 ? 219.772 206.821 203.365 1.00 69.12  ? 389 MET B C   1 
ATOM   9154  O  O   . MET B 1 389 ? 218.557 206.648 203.490 1.00 65.91  ? 389 MET B O   1 
ATOM   9155  C  CB  . MET B 1 389 ? 221.502 207.364 205.080 1.00 81.94  ? 389 MET B CB  1 
ATOM   9156  C  CG  . MET B 1 389 ? 220.648 208.536 205.561 1.00 81.45  ? 389 MET B CG  1 
ATOM   9157  S  SD  . MET B 1 389 ? 219.269 208.181 206.652 1.00 92.71  ? 389 MET B SD  1 
ATOM   9158  C  CE  . MET B 1 389 ? 220.055 207.122 207.843 1.00 80.80  ? 389 MET B CE  1 
ATOM   9159  N  N   . THR B 1 390 ? 220.296 207.529 202.364 1.00 70.18  ? 390 THR B N   1 
ATOM   9160  C  CA  . THR B 1 390 ? 219.497 208.136 201.314 1.00 70.66  ? 390 THR B CA  1 
ATOM   9161  C  C   . THR B 1 390 ? 219.747 207.546 199.940 1.00 70.40  ? 390 THR B C   1 
ATOM   9162  O  O   . THR B 1 390 ? 218.919 207.748 199.046 1.00 72.16  ? 390 THR B O   1 
ATOM   9163  C  CB  . THR B 1 390 ? 219.762 209.646 201.234 1.00 72.11  ? 390 THR B CB  1 
ATOM   9164  O  OG1 . THR B 1 390 ? 220.923 209.877 200.431 1.00 70.97  ? 390 THR B OG1 1 
ATOM   9165  C  CG2 . THR B 1 390 ? 220.000 210.225 202.608 1.00 72.72  ? 390 THR B CG2 1 
ATOM   9166  N  N   . GLY B 1 391 ? 220.853 206.834 199.742 1.00 68.83  ? 391 GLY B N   1 
ATOM   9167  C  CA  . GLY B 1 391 ? 221.187 206.254 198.462 1.00 65.72  ? 391 GLY B CA  1 
ATOM   9168  C  C   . GLY B 1 391 ? 222.251 206.995 197.687 1.00 62.25  ? 391 GLY B C   1 
ATOM   9169  O  O   . GLY B 1 391 ? 222.698 206.491 196.652 1.00 60.27  ? 391 GLY B O   1 
ATOM   9170  N  N   . LEU B 1 392 ? 222.656 208.175 198.144 1.00 59.37  ? 392 LEU B N   1 
ATOM   9171  C  CA  . LEU B 1 392 ? 223.708 208.915 197.478 1.00 52.36  ? 392 LEU B CA  1 
ATOM   9172  C  C   . LEU B 1 392 ? 225.038 208.196 197.659 1.00 51.51  ? 392 LEU B C   1 
ATOM   9173  O  O   . LEU B 1 392 ? 225.194 207.387 198.570 1.00 55.25  ? 392 LEU B O   1 
ATOM   9174  C  CB  . LEU B 1 392 ? 223.784 210.327 198.036 1.00 54.38  ? 392 LEU B CB  1 
ATOM   9175  C  CG  . LEU B 1 392 ? 222.487 211.118 197.928 1.00 58.40  ? 392 LEU B CG  1 
ATOM   9176  C  CD1 . LEU B 1 392 ? 222.695 212.522 198.447 1.00 58.26  ? 392 LEU B CD1 1 
ATOM   9177  C  CD2 . LEU B 1 392 ? 222.012 211.140 196.497 1.00 60.70  ? 392 LEU B CD2 1 
ATOM   9178  N  N   . PRO B 1 393 ? 226.004 208.445 196.788 1.00 49.86  ? 393 PRO B N   1 
ATOM   9179  C  CA  . PRO B 1 393 ? 227.294 207.772 196.925 1.00 51.70  ? 393 PRO B CA  1 
ATOM   9180  C  C   . PRO B 1 393 ? 228.083 208.300 198.111 1.00 55.29  ? 393 PRO B C   1 
ATOM   9181  O  O   . PRO B 1 393 ? 227.812 209.375 198.649 1.00 56.21  ? 393 PRO B O   1 
ATOM   9182  C  CB  . PRO B 1 393 ? 228.001 208.086 195.609 1.00 53.42  ? 393 PRO B CB  1 
ATOM   9183  C  CG  . PRO B 1 393 ? 226.959 208.610 194.700 1.00 54.01  ? 393 PRO B CG  1 
ATOM   9184  C  CD  . PRO B 1 393 ? 225.928 209.237 195.556 1.00 54.38  ? 393 PRO B CD  1 
ATOM   9185  N  N   . ASN B 1 394 ? 229.079 207.519 198.519 1.00 61.43  ? 394 ASN B N   1 
ATOM   9186  C  CA  . ASN B 1 394 ? 229.956 207.908 199.611 1.00 59.92  ? 394 ASN B CA  1 
ATOM   9187  C  C   . ASN B 1 394 ? 231.229 208.559 199.073 1.00 60.84  ? 394 ASN B C   1 
ATOM   9188  O  O   . ASN B 1 394 ? 231.397 208.764 197.871 1.00 62.53  ? 394 ASN B O   1 
ATOM   9189  C  CB  . ASN B 1 394 ? 230.225 206.708 200.528 1.00 67.85  ? 394 ASN B CB  1 
ATOM   9190  C  CG  . ASN B 1 394 ? 231.525 205.952 200.207 1.00 75.58  ? 394 ASN B CG  1 
ATOM   9191  O  OD1 . ASN B 1 394 ? 232.088 206.044 199.117 1.00 76.69  ? 394 ASN B OD1 1 
ATOM   9192  N  ND2 . ASN B 1 394 ? 232.006 205.200 201.191 1.00 74.66  ? 394 ASN B ND2 1 
ATOM   9193  N  N   . ARG B 1 395 ? 232.146 208.873 199.988 1.00 62.36  ? 395 ARG B N   1 
ATOM   9194  C  CA  . ARG B 1 395 ? 233.325 209.651 199.630 1.00 66.87  ? 395 ARG B CA  1 
ATOM   9195  C  C   . ARG B 1 395 ? 234.183 208.946 198.597 1.00 71.56  ? 395 ARG B C   1 
ATOM   9196  O  O   . ARG B 1 395 ? 234.808 209.605 197.760 1.00 76.12  ? 395 ARG B O   1 
ATOM   9197  C  CB  . ARG B 1 395 ? 234.150 209.952 200.879 1.00 68.51  ? 395 ARG B CB  1 
ATOM   9198  C  CG  . ARG B 1 395 ? 234.920 211.252 200.803 1.00 69.07  ? 395 ARG B CG  1 
ATOM   9199  C  CD  . ARG B 1 395 ? 235.499 211.637 202.152 1.00 71.39  ? 395 ARG B CD  1 
ATOM   9200  N  NE  . ARG B 1 395 ? 235.939 213.026 202.170 1.00 72.86  ? 395 ARG B NE  1 
ATOM   9201  C  CZ  . ARG B 1 395 ? 236.061 213.758 203.267 1.00 70.32  ? 395 ARG B CZ  1 
ATOM   9202  N  NH1 . ARG B 1 395 ? 235.777 213.265 204.462 1.00 64.86  ? 395 ARG B NH1 1 
ATOM   9203  N  NH2 . ARG B 1 395 ? 236.471 215.018 203.164 1.00 73.97  ? 395 ARG B NH2 1 
ATOM   9204  N  N   . ASN B 1 396 ? 234.240 207.616 198.643 1.00 72.65  ? 396 ASN B N   1 
ATOM   9205  C  CA  . ASN B 1 396 ? 235.046 206.889 197.673 1.00 77.43  ? 396 ASN B CA  1 
ATOM   9206  C  C   . ASN B 1 396 ? 234.521 207.104 196.260 1.00 79.35  ? 396 ASN B C   1 
ATOM   9207  O  O   . ASN B 1 396 ? 235.303 207.271 195.317 1.00 80.70  ? 396 ASN B O   1 
ATOM   9208  C  CB  . ASN B 1 396 ? 235.072 205.405 198.023 1.00 78.65  ? 396 ASN B CB  1 
ATOM   9209  C  CG  . ASN B 1 396 ? 235.509 205.156 199.450 1.00 81.77  ? 396 ASN B CG  1 
ATOM   9210  O  OD1 . ASN B 1 396 ? 234.972 204.284 200.132 1.00 81.05  ? 396 ASN B OD1 1 
ATOM   9211  N  ND2 . ASN B 1 396 ? 236.486 205.926 199.913 1.00 81.63  ? 396 ASN B ND2 1 
ATOM   9212  N  N   . ASN B 1 397 ? 233.198 207.111 196.095 1.00 75.60  ? 397 ASN B N   1 
ATOM   9213  C  CA  . ASN B 1 397 ? 232.630 207.329 194.771 1.00 74.60  ? 397 ASN B CA  1 
ATOM   9214  C  C   . ASN B 1 397 ? 232.961 208.720 194.258 1.00 75.94  ? 397 ASN B C   1 
ATOM   9215  O  O   . ASN B 1 397 ? 233.275 208.893 193.075 1.00 78.87  ? 397 ASN B O   1 
ATOM   9216  C  CB  . ASN B 1 397 ? 231.122 207.128 194.805 1.00 69.49  ? 397 ASN B CB  1 
ATOM   9217  C  CG  . ASN B 1 397 ? 230.499 207.199 193.430 1.00 73.37  ? 397 ASN B CG  1 
ATOM   9218  O  OD1 . ASN B 1 397 ? 231.083 207.745 192.498 1.00 73.20  ? 397 ASN B OD1 1 
ATOM   9219  N  ND2 . ASN B 1 397 ? 229.298 206.650 193.298 1.00 73.16  ? 397 ASN B ND2 1 
ATOM   9220  N  N   . LEU B 1 398 ? 232.888 209.726 195.131 1.00 72.57  ? 398 LEU B N   1 
ATOM   9221  C  CA  . LEU B 1 398 ? 233.268 211.075 194.727 1.00 70.50  ? 398 LEU B CA  1 
ATOM   9222  C  C   . LEU B 1 398 ? 234.732 211.131 194.333 1.00 74.17  ? 398 LEU B C   1 
ATOM   9223  O  O   . LEU B 1 398 ? 235.093 211.790 193.350 1.00 80.25  ? 398 LEU B O   1 
ATOM   9224  C  CB  . LEU B 1 398 ? 232.987 212.068 195.850 1.00 64.54  ? 398 LEU B CB  1 
ATOM   9225  C  CG  . LEU B 1 398 ? 233.489 213.471 195.534 1.00 62.29  ? 398 LEU B CG  1 
ATOM   9226  C  CD1 . LEU B 1 398 ? 232.771 214.038 194.327 1.00 60.27  ? 398 LEU B CD1 1 
ATOM   9227  C  CD2 . LEU B 1 398 ? 233.358 214.386 196.725 1.00 63.78  ? 398 LEU B CD2 1 
ATOM   9228  N  N   . HIS B 1 399 ? 235.594 210.451 195.088 1.00 71.50  ? 399 HIS B N   1 
ATOM   9229  C  CA  . HIS B 1 399 ? 237.008 210.444 194.743 1.00 74.43  ? 399 HIS B CA  1 
ATOM   9230  C  C   . HIS B 1 399 ? 237.231 209.832 193.368 1.00 78.68  ? 399 HIS B C   1 
ATOM   9231  O  O   . HIS B 1 399 ? 237.930 210.413 192.529 1.00 81.90  ? 399 HIS B O   1 
ATOM   9232  C  CB  . HIS B 1 399 ? 237.808 209.698 195.806 1.00 74.98  ? 399 HIS B CB  1 
ATOM   9233  C  CG  . HIS B 1 399 ? 237.766 210.338 197.158 1.00 79.02  ? 399 HIS B CG  1 
ATOM   9234  N  ND1 . HIS B 1 399 ? 237.649 211.699 197.335 1.00 78.87  ? 399 HIS B ND1 1 
ATOM   9235  C  CD2 . HIS B 1 399 ? 237.836 209.803 198.400 1.00 79.31  ? 399 HIS B CD2 1 
ATOM   9236  C  CE1 . HIS B 1 399 ? 237.644 211.975 198.627 1.00 76.27  ? 399 HIS B CE1 1 
ATOM   9237  N  NE2 . HIS B 1 399 ? 237.756 210.842 199.295 1.00 76.07  ? 399 HIS B NE2 1 
ATOM   9238  N  N   . ASN B 1 400 ? 236.616 208.678 193.105 1.00 75.59  ? 400 ASN B N   1 
ATOM   9239  C  CA  . ASN B 1 400 ? 236.787 208.046 191.800 1.00 76.36  ? 400 ASN B CA  1 
ATOM   9240  C  C   . ASN B 1 400 ? 236.217 208.907 190.682 1.00 75.23  ? 400 ASN B C   1 
ATOM   9241  O  O   . ASN B 1 400 ? 236.801 208.988 189.597 1.00 80.61  ? 400 ASN B O   1 
ATOM   9242  C  CB  . ASN B 1 400 ? 236.154 206.656 191.781 1.00 81.54  ? 400 ASN B CB  1 
ATOM   9243  C  CG  . ASN B 1 400 ? 236.397 205.884 193.057 1.00 86.31  ? 400 ASN B CG  1 
ATOM   9244  O  OD1 . ASN B 1 400 ? 237.306 206.202 193.824 1.00 87.30  ? 400 ASN B OD1 1 
ATOM   9245  N  ND2 . ASN B 1 400 ? 235.583 204.862 193.295 1.00 82.24  ? 400 ASN B ND2 1 
ATOM   9246  N  N   . TYR B 1 401 ? 235.075 209.550 190.920 1.00 71.27  ? 401 TYR B N   1 
ATOM   9247  C  CA  . TYR B 1 401 ? 234.446 210.335 189.867 1.00 69.56  ? 401 TYR B CA  1 
ATOM   9248  C  C   . TYR B 1 401 ? 235.303 211.549 189.534 1.00 74.18  ? 401 TYR B C   1 
ATOM   9249  O  O   . TYR B 1 401 ? 235.568 211.834 188.360 1.00 77.33  ? 401 TYR B O   1 
ATOM   9250  C  CB  . TYR B 1 401 ? 233.032 210.723 190.312 1.00 62.13  ? 401 TYR B CB  1 
ATOM   9251  C  CG  . TYR B 1 401 ? 232.185 211.565 189.369 1.00 60.72  ? 401 TYR B CG  1 
ATOM   9252  C  CD1 . TYR B 1 401 ? 232.695 212.127 188.214 1.00 69.15  ? 401 TYR B CD1 1 
ATOM   9253  C  CD2 . TYR B 1 401 ? 230.846 211.748 189.626 1.00 57.01  ? 401 TYR B CD2 1 
ATOM   9254  C  CE1 . TYR B 1 401 ? 231.909 212.871 187.372 1.00 70.99  ? 401 TYR B CE1 1 
ATOM   9255  C  CE2 . TYR B 1 401 ? 230.060 212.475 188.784 1.00 63.20  ? 401 TYR B CE2 1 
ATOM   9256  C  CZ  . TYR B 1 401 ? 230.590 213.045 187.667 1.00 71.71  ? 401 TYR B CZ  1 
ATOM   9257  O  OH  . TYR B 1 401 ? 229.787 213.781 186.830 1.00 78.10  ? 401 TYR B OH  1 
ATOM   9258  N  N   . LEU B 1 402 ? 235.782 212.257 190.555 1.00 74.20  ? 402 LEU B N   1 
ATOM   9259  C  CA  . LEU B 1 402 ? 236.660 213.388 190.293 1.00 76.17  ? 402 LEU B CA  1 
ATOM   9260  C  C   . LEU B 1 402 ? 237.942 212.935 189.614 1.00 79.15  ? 402 LEU B C   1 
ATOM   9261  O  O   . LEU B 1 402 ? 238.472 213.638 188.748 1.00 84.38  ? 402 LEU B O   1 
ATOM   9262  C  CB  . LEU B 1 402 ? 236.964 214.140 191.587 1.00 77.26  ? 402 LEU B CB  1 
ATOM   9263  C  CG  . LEU B 1 402 ? 235.867 215.098 192.047 1.00 71.18  ? 402 LEU B CG  1 
ATOM   9264  C  CD1 . LEU B 1 402 ? 236.196 215.686 193.404 1.00 72.78  ? 402 LEU B CD1 1 
ATOM   9265  C  CD2 . LEU B 1 402 ? 235.689 216.189 191.034 1.00 64.68  ? 402 LEU B CD2 1 
ATOM   9266  N  N   . ASP B 1 403 ? 238.460 211.764 189.988 1.00 75.33  ? 403 ASP B N   1 
ATOM   9267  C  CA  . ASP B 1 403 ? 239.672 211.276 189.342 1.00 79.09  ? 403 ASP B CA  1 
ATOM   9268  C  C   . ASP B 1 403 ? 239.433 210.973 187.868 1.00 86.12  ? 403 ASP B C   1 
ATOM   9269  O  O   . ASP B 1 403 ? 240.278 211.285 187.021 1.00 89.46  ? 403 ASP B O   1 
ATOM   9270  C  CB  . ASP B 1 403 ? 240.191 210.042 190.071 1.00 77.77  ? 403 ASP B CB  1 
ATOM   9271  C  CG  . ASP B 1 403 ? 240.727 210.368 191.442 1.00 83.08  ? 403 ASP B CG  1 
ATOM   9272  O  OD1 . ASP B 1 403 ? 240.646 211.548 191.840 1.00 83.91  ? 403 ASP B OD1 1 
ATOM   9273  O  OD2 . ASP B 1 403 ? 241.234 209.452 192.120 1.00 85.42  ? 403 ASP B OD2 1 
ATOM   9274  N  N   . ASP B 1 404 ? 238.291 210.365 187.543 1.00 87.78  ? 404 ASP B N   1 
ATOM   9275  C  CA  . ASP B 1 404 ? 237.939 210.131 186.147 1.00 91.50  ? 404 ASP B CA  1 
ATOM   9276  C  C   . ASP B 1 404 ? 237.665 211.428 185.400 1.00 89.23  ? 404 ASP B C   1 
ATOM   9277  O  O   . ASP B 1 404 ? 237.756 211.454 184.170 1.00 93.96  ? 404 ASP B O   1 
ATOM   9278  C  CB  . ASP B 1 404 ? 236.720 209.212 186.052 1.00 93.59  ? 404 ASP B CB  1 
ATOM   9279  C  CG  . ASP B 1 404 ? 236.574 208.579 184.682 1.00 101.56 ? 404 ASP B CG  1 
ATOM   9280  O  OD1 . ASP B 1 404 ? 237.600 208.417 183.988 1.00 102.95 ? 404 ASP B OD1 1 
ATOM   9281  O  OD2 . ASP B 1 404 ? 235.433 208.247 184.297 1.00 104.81 ? 404 ASP B OD2 1 
ATOM   9282  N  N   . LEU B 1 405 ? 237.306 212.493 186.112 1.00 82.10  ? 405 LEU B N   1 
ATOM   9283  C  CA  . LEU B 1 405 ? 237.190 213.793 185.466 1.00 83.11  ? 405 LEU B CA  1 
ATOM   9284  C  C   . LEU B 1 405 ? 238.561 214.403 185.195 1.00 83.46  ? 405 LEU B C   1 
ATOM   9285  O  O   . LEU B 1 405 ? 238.771 215.041 184.158 1.00 83.85  ? 405 LEU B O   1 
ATOM   9286  C  CB  . LEU B 1 405 ? 236.358 214.731 186.336 1.00 80.32  ? 405 LEU B CB  1 
ATOM   9287  C  CG  . LEU B 1 405 ? 234.847 214.523 186.346 1.00 79.89  ? 405 LEU B CG  1 
ATOM   9288  C  CD1 . LEU B 1 405 ? 234.205 215.457 187.348 1.00 76.15  ? 405 LEU B CD1 1 
ATOM   9289  C  CD2 . LEU B 1 405 ? 234.268 214.758 184.974 1.00 80.29  ? 405 LEU B CD2 1 
ATOM   9290  N  N   . VAL B 1 406 ? 239.500 214.219 186.120 1.00 82.99  ? 406 VAL B N   1 
ATOM   9291  C  CA  . VAL B 1 406 ? 240.783 214.902 186.032 1.00 87.25  ? 406 VAL B CA  1 
ATOM   9292  C  C   . VAL B 1 406 ? 241.624 214.336 184.898 1.00 91.28  ? 406 VAL B C   1 
ATOM   9293  O  O   . VAL B 1 406 ? 242.236 215.088 184.130 1.00 94.89  ? 406 VAL B O   1 
ATOM   9294  C  CB  . VAL B 1 406 ? 241.518 214.817 187.381 1.00 90.82  ? 406 VAL B CB  1 
ATOM   9295  C  CG1 . VAL B 1 406 ? 243.016 215.007 187.193 1.00 91.45  ? 406 VAL B CG1 1 
ATOM   9296  C  CG2 . VAL B 1 406 ? 240.966 215.853 188.345 1.00 92.49  ? 406 VAL B CG2 1 
ATOM   9297  N  N   . ASP B 1 407 ? 241.667 213.007 184.767 1.00 93.11  ? 407 ASP B N   1 
ATOM   9298  C  CA  . ASP B 1 407 ? 242.605 212.396 183.831 1.00 98.80  ? 407 ASP B CA  1 
ATOM   9299  C  C   . ASP B 1 407 ? 242.313 212.794 182.390 1.00 98.49  ? 407 ASP B C   1 
ATOM   9300  O  O   . ASP B 1 407 ? 243.226 212.819 181.558 1.00 100.23 ? 407 ASP B O   1 
ATOM   9301  C  CB  . ASP B 1 407 ? 242.591 210.873 183.979 1.00 101.01 ? 407 ASP B CB  1 
ATOM   9302  C  CG  . ASP B 1 407 ? 241.309 210.243 183.466 1.00 102.52 ? 407 ASP B CG  1 
ATOM   9303  O  OD1 . ASP B 1 407 ? 240.291 210.955 183.351 1.00 101.63 ? 407 ASP B OD1 1 
ATOM   9304  O  OD2 . ASP B 1 407 ? 241.322 209.028 183.175 1.00 102.54 ? 407 ASP B OD2 1 
ATOM   9305  N  N   . LYS B 1 408 ? 241.059 213.115 182.076 1.00 94.83  ? 408 LYS B N   1 
ATOM   9306  C  CA  . LYS B 1 408 ? 240.687 213.541 180.736 1.00 94.36  ? 408 LYS B CA  1 
ATOM   9307  C  C   . LYS B 1 408 ? 240.519 215.052 180.632 1.00 94.00  ? 408 LYS B C   1 
ATOM   9308  O  O   . LYS B 1 408 ? 239.870 215.535 179.700 1.00 94.48  ? 408 LYS B O   1 
ATOM   9309  C  CB  . LYS B 1 408 ? 239.423 212.813 180.279 1.00 94.10  ? 408 LYS B CB  1 
ATOM   9310  C  CG  . LYS B 1 408 ? 238.227 212.951 181.190 1.00 95.35  ? 408 LYS B CG  1 
ATOM   9311  C  CD  . LYS B 1 408 ? 236.945 212.871 180.382 1.00 93.68  ? 408 LYS B CD  1 
ATOM   9312  C  CE  . LYS B 1 408 ? 235.871 213.762 180.962 1.00 93.22  ? 408 LYS B CE  1 
ATOM   9313  N  NZ  . LYS B 1 408 ? 235.614 213.413 182.381 1.00 93.79  ? 408 LYS B NZ  1 
ATOM   9314  N  N   . ALA B 1 409 ? 241.082 215.798 181.584 1.00 90.87  ? 409 ALA B N   1 
ATOM   9315  C  CA  . ALA B 1 409 ? 241.271 217.245 181.462 1.00 93.14  ? 409 ALA B CA  1 
ATOM   9316  C  C   . ALA B 1 409 ? 239.949 217.995 181.328 1.00 94.89  ? 409 ALA B C   1 
ATOM   9317  O  O   . ALA B 1 409 ? 239.711 218.699 180.345 1.00 96.75  ? 409 ALA B O   1 
ATOM   9318  C  CB  . ALA B 1 409 ? 242.201 217.579 180.292 1.00 92.48  ? 409 ALA B CB  1 
ATOM   9319  N  N   . VAL B 1 410 ? 239.076 217.843 182.320 1.00 92.15  ? 410 VAL B N   1 
ATOM   9320  C  CA  . VAL B 1 410 ? 237.862 218.642 182.434 1.00 88.94  ? 410 VAL B CA  1 
ATOM   9321  C  C   . VAL B 1 410 ? 237.798 219.209 183.845 1.00 88.30  ? 410 VAL B C   1 
ATOM   9322  O  O   . VAL B 1 410 ? 238.032 218.487 184.821 1.00 86.86  ? 410 VAL B O   1 
ATOM   9323  C  CB  . VAL B 1 410 ? 236.604 217.823 182.104 1.00 85.50  ? 410 VAL B CB  1 
ATOM   9324  C  CG1 . VAL B 1 410 ? 235.374 218.702 182.180 1.00 82.35  ? 410 VAL B CG1 1 
ATOM   9325  C  CG2 . VAL B 1 410 ? 236.724 217.221 180.717 1.00 85.49  ? 410 VAL B CG2 1 
ATOM   9326  N  N   . SER B 1 411 ? 237.492 220.504 183.950 1.00 82.67  ? 411 SER B N   1 
ATOM   9327  C  CA  . SER B 1 411 ? 237.461 221.181 185.238 1.00 71.97  ? 411 SER B CA  1 
ATOM   9328  C  C   . SER B 1 411 ? 236.060 221.099 185.819 1.00 63.37  ? 411 SER B C   1 
ATOM   9329  O  O   . SER B 1 411 ? 235.130 221.681 185.245 1.00 65.84  ? 411 SER B O   1 
ATOM   9330  C  CB  . SER B 1 411 ? 237.881 222.630 185.087 1.00 72.34  ? 411 SER B CB  1 
ATOM   9331  O  OG  . SER B 1 411 ? 237.138 223.262 184.061 1.00 69.82  ? 411 SER B OG  1 
ATOM   9332  N  N   . PRO B 1 412 ? 235.857 220.403 186.916 1.00 55.46  ? 412 PRO B N   1 
ATOM   9333  C  CA  . PRO B 1 412 ? 234.533 220.360 187.536 1.00 53.55  ? 412 PRO B CA  1 
ATOM   9334  C  C   . PRO B 1 412 ? 234.349 221.422 188.597 1.00 52.00  ? 412 PRO B C   1 
ATOM   9335  O  O   . PRO B 1 412 ? 235.165 221.546 189.512 1.00 55.57  ? 412 PRO B O   1 
ATOM   9336  C  CB  . PRO B 1 412 ? 234.493 218.961 188.145 1.00 63.29  ? 412 PRO B CB  1 
ATOM   9337  C  CG  . PRO B 1 412 ? 235.922 218.687 188.498 1.00 68.68  ? 412 PRO B CG  1 
ATOM   9338  C  CD  . PRO B 1 412 ? 236.804 219.504 187.589 1.00 62.95  ? 412 PRO B CD  1 
ATOM   9339  N  N   . VAL B 1 413 ? 233.276 222.187 188.498 1.00 53.38  ? 413 VAL B N   1 
ATOM   9340  C  CA  . VAL B 1 413 ? 232.913 223.111 189.559 1.00 52.62  ? 413 VAL B CA  1 
ATOM   9341  C  C   . VAL B 1 413 ? 232.356 222.301 190.717 1.00 54.78  ? 413 VAL B C   1 
ATOM   9342  O  O   . VAL B 1 413 ? 231.428 221.495 190.539 1.00 59.36  ? 413 VAL B O   1 
ATOM   9343  C  CB  . VAL B 1 413 ? 231.895 224.144 189.058 1.00 51.75  ? 413 VAL B CB  1 
ATOM   9344  C  CG1 . VAL B 1 413 ? 231.844 225.315 189.992 1.00 50.53  ? 413 VAL B CG1 1 
ATOM   9345  C  CG2 . VAL B 1 413 ? 232.266 224.604 187.666 1.00 60.17  ? 413 VAL B CG2 1 
ATOM   9346  N  N   . VAL B 1 414 ? 232.925 222.502 191.904 1.00 50.81  ? 414 VAL B N   1 
ATOM   9347  C  CA  . VAL B 1 414 ? 232.620 221.690 193.074 1.00 44.13  ? 414 VAL B CA  1 
ATOM   9348  C  C   . VAL B 1 414 ? 231.956 222.573 194.110 1.00 41.86  ? 414 VAL B C   1 
ATOM   9349  O  O   . VAL B 1 414 ? 232.554 223.552 194.574 1.00 50.80  ? 414 VAL B O   1 
ATOM   9350  C  CB  . VAL B 1 414 ? 233.885 221.049 193.655 1.00 47.70  ? 414 VAL B CB  1 
ATOM   9351  C  CG1 . VAL B 1 414 ? 233.575 220.410 194.986 1.00 47.45  ? 414 VAL B CG1 1 
ATOM   9352  C  CG2 . VAL B 1 414 ? 234.457 220.037 192.690 1.00 55.17  ? 414 VAL B CG2 1 
ATOM   9353  N  N   . TYR B 1 415 ? 230.735 222.229 194.487 1.00 38.59  ? 415 TYR B N   1 
ATOM   9354  C  CA  . TYR B 1 415 ? 230.052 222.882 195.588 1.00 42.70  ? 415 TYR B CA  1 
ATOM   9355  C  C   . TYR B 1 415 ? 230.079 221.959 196.791 1.00 45.04  ? 415 TYR B C   1 
ATOM   9356  O  O   . TYR B 1 415 ? 229.717 220.784 196.686 1.00 53.01  ? 415 TYR B O   1 
ATOM   9357  C  CB  . TYR B 1 415 ? 228.599 223.233 195.256 1.00 49.63  ? 415 TYR B CB  1 
ATOM   9358  C  CG  . TYR B 1 415 ? 228.339 223.837 193.895 1.00 54.05  ? 415 TYR B CG  1 
ATOM   9359  C  CD1 . TYR B 1 415 ? 229.319 224.537 193.213 1.00 54.27  ? 415 TYR B CD1 1 
ATOM   9360  C  CD2 . TYR B 1 415 ? 227.091 223.741 193.314 1.00 52.44  ? 415 TYR B CD2 1 
ATOM   9361  C  CE1 . TYR B 1 415 ? 229.065 225.089 191.977 1.00 50.71  ? 415 TYR B CE1 1 
ATOM   9362  C  CE2 . TYR B 1 415 ? 226.836 224.294 192.087 1.00 50.39  ? 415 TYR B CE2 1 
ATOM   9363  C  CZ  . TYR B 1 415 ? 227.823 224.970 191.425 1.00 51.25  ? 415 TYR B CZ  1 
ATOM   9364  O  OH  . TYR B 1 415 ? 227.571 225.522 190.194 1.00 56.73  ? 415 TYR B OH  1 
ATOM   9365  N  N   . LEU B 1 416 ? 230.509 222.490 197.925 1.00 42.68  ? 416 LEU B N   1 
ATOM   9366  C  CA  . LEU B 1 416 ? 230.447 221.790 199.195 1.00 39.92  ? 416 LEU B CA  1 
ATOM   9367  C  C   . LEU B 1 416 ? 229.336 222.423 200.006 1.00 40.76  ? 416 LEU B C   1 
ATOM   9368  O  O   . LEU B 1 416 ? 229.404 223.609 200.329 1.00 50.49  ? 416 LEU B O   1 
ATOM   9369  C  CB  . LEU B 1 416 ? 231.780 221.876 199.927 1.00 44.35  ? 416 LEU B CB  1 
ATOM   9370  C  CG  . LEU B 1 416 ? 232.092 220.695 200.830 1.00 52.31  ? 416 LEU B CG  1 
ATOM   9371  C  CD1 . LEU B 1 416 ? 233.583 220.543 200.993 1.00 60.38  ? 416 LEU B CD1 1 
ATOM   9372  C  CD2 . LEU B 1 416 ? 231.431 220.880 202.167 1.00 56.26  ? 416 LEU B CD2 1 
ATOM   9373  N  N   . ILE B 1 417 ? 228.326 221.633 200.339 1.00 40.19  ? 417 ILE B N   1 
ATOM   9374  C  CA  . ILE B 1 417 ? 227.156 222.110 201.059 1.00 46.42  ? 417 ILE B CA  1 
ATOM   9375  C  C   . ILE B 1 417 ? 227.222 221.568 202.474 1.00 50.44  ? 417 ILE B C   1 
ATOM   9376  O  O   . ILE B 1 417 ? 227.306 220.351 202.678 1.00 56.47  ? 417 ILE B O   1 
ATOM   9377  C  CB  . ILE B 1 417 ? 225.850 221.677 200.380 1.00 51.71  ? 417 ILE B CB  1 
ATOM   9378  C  CG1 . ILE B 1 417 ? 225.913 221.937 198.879 1.00 53.48  ? 417 ILE B CG1 1 
ATOM   9379  C  CG2 . ILE B 1 417 ? 224.677 222.409 200.995 1.00 55.48  ? 417 ILE B CG2 1 
ATOM   9380  C  CD1 . ILE B 1 417 ? 224.928 221.111 198.085 1.00 54.58  ? 417 ILE B CD1 1 
ATOM   9381  N  N   . GLY B 1 418 ? 227.183 222.468 203.449 1.00 53.47  ? 418 GLY B N   1 
ATOM   9382  C  CA  . GLY B 1 418 ? 227.065 222.106 204.844 1.00 56.89  ? 418 GLY B CA  1 
ATOM   9383  C  C   . GLY B 1 418 ? 225.700 222.529 205.358 1.00 62.80  ? 418 GLY B C   1 
ATOM   9384  O  O   . GLY B 1 418 ? 225.308 223.689 205.219 1.00 68.11  ? 418 GLY B O   1 
ATOM   9385  N  N   . VAL B 1 419 ? 224.983 221.572 205.917 1.00 61.23  ? 419 VAL B N   1 
ATOM   9386  C  CA  . VAL B 1 419 ? 223.681 221.851 206.500 1.00 69.01  ? 419 VAL B CA  1 
ATOM   9387  C  C   . VAL B 1 419 ? 223.879 222.382 207.912 1.00 75.60  ? 419 VAL B C   1 
ATOM   9388  O  O   . VAL B 1 419 ? 224.695 221.860 208.679 1.00 78.84  ? 419 VAL B O   1 
ATOM   9389  C  CB  . VAL B 1 419 ? 222.803 220.593 206.481 1.00 68.82  ? 419 VAL B CB  1 
ATOM   9390  C  CG1 . VAL B 1 419 ? 221.417 220.923 206.974 1.00 71.94  ? 419 VAL B CG1 1 
ATOM   9391  C  CG2 . VAL B 1 419 ? 222.746 220.019 205.079 1.00 66.18  ? 419 VAL B CG2 1 
ATOM   9392  N  N   . ASP B 1 420 ? 223.131 223.427 208.260 1.00 75.18  ? 420 ASP B N   1 
ATOM   9393  C  CA  . ASP B 1 420 ? 223.350 224.179 209.482 1.00 73.44  ? 420 ASP B CA  1 
ATOM   9394  C  C   . ASP B 1 420 ? 222.069 224.256 210.294 1.00 75.58  ? 420 ASP B C   1 
ATOM   9395  O  O   . ASP B 1 420 ? 220.963 224.221 209.744 1.00 77.93  ? 420 ASP B O   1 
ATOM   9396  C  CB  . ASP B 1 420 ? 223.848 225.584 209.177 1.00 72.79  ? 420 ASP B CB  1 
ATOM   9397  C  CG  . ASP B 1 420 ? 225.332 225.626 208.930 1.00 75.78  ? 420 ASP B CG  1 
ATOM   9398  O  OD1 . ASP B 1 420 ? 225.987 224.588 209.138 1.00 79.51  ? 420 ASP B OD1 1 
ATOM   9399  O  OD2 . ASP B 1 420 ? 225.847 226.689 208.531 1.00 74.21  ? 420 ASP B OD2 1 
ATOM   9400  N  N   . HIS B 1 421 ? 222.246 224.400 211.610 1.00 75.65  ? 421 HIS B N   1 
ATOM   9401  C  CA  . HIS B 1 421 ? 221.203 224.344 212.634 1.00 76.72  ? 421 HIS B CA  1 
ATOM   9402  C  C   . HIS B 1 421 ? 220.649 222.943 212.830 1.00 83.32  ? 421 HIS B C   1 
ATOM   9403  O  O   . HIS B 1 421 ? 219.491 222.792 213.229 1.00 89.24  ? 421 HIS B O   1 
ATOM   9404  C  CB  . HIS B 1 421 ? 220.037 225.308 212.378 1.00 79.27  ? 421 HIS B CB  1 
ATOM   9405  C  CG  . HIS B 1 421 ? 220.442 226.644 211.838 1.00 86.55  ? 421 HIS B CG  1 
ATOM   9406  N  ND1 . HIS B 1 421 ? 219.524 227.556 211.364 1.00 89.49  ? 421 HIS B ND1 1 
ATOM   9407  C  CD2 . HIS B 1 421 ? 221.651 227.246 211.744 1.00 87.30  ? 421 HIS B CD2 1 
ATOM   9408  C  CE1 . HIS B 1 421 ? 220.153 228.649 210.972 1.00 88.12  ? 421 HIS B CE1 1 
ATOM   9409  N  NE2 . HIS B 1 421 ? 221.445 228.487 211.190 1.00 87.36  ? 421 HIS B NE2 1 
ATOM   9410  N  N   . ILE B 1 422 ? 221.444 221.907 212.562 1.00 83.43  ? 422 ILE B N   1 
ATOM   9411  C  CA  . ILE B 1 422 ? 221.023 220.553 212.893 1.00 85.59  ? 422 ILE B CA  1 
ATOM   9412  C  C   . ILE B 1 422 ? 221.243 220.254 214.361 1.00 87.90  ? 422 ILE B C   1 
ATOM   9413  O  O   . ILE B 1 422 ? 220.650 219.305 214.896 1.00 89.24  ? 422 ILE B O   1 
ATOM   9414  C  CB  . ILE B 1 422 ? 221.792 219.497 212.093 1.00 84.76  ? 422 ILE B CB  1 
ATOM   9415  C  CG1 . ILE B 1 422 ? 223.287 219.721 212.288 1.00 81.41  ? 422 ILE B CG1 1 
ATOM   9416  C  CG2 . ILE B 1 422 ? 221.421 219.568 210.629 1.00 80.66  ? 422 ILE B CG2 1 
ATOM   9417  C  CD1 . ILE B 1 422 ? 224.125 218.608 211.774 1.00 82.06  ? 422 ILE B CD1 1 
ATOM   9418  N  N   . GLN B 1 423 ? 222.110 221.025 215.016 1.00 85.76  ? 423 GLN B N   1 
ATOM   9419  C  CA  . GLN B 1 423 ? 222.415 220.760 216.410 1.00 83.20  ? 423 GLN B CA  1 
ATOM   9420  C  C   . GLN B 1 423 ? 221.171 220.871 217.268 1.00 86.24  ? 423 GLN B C   1 
ATOM   9421  O  O   . GLN B 1 423 ? 221.048 220.169 218.275 1.00 87.89  ? 423 GLN B O   1 
ATOM   9422  C  CB  . GLN B 1 423 ? 223.489 221.724 216.896 1.00 85.36  ? 423 GLN B CB  1 
ATOM   9423  C  CG  . GLN B 1 423 ? 224.404 221.116 217.910 1.00 85.50  ? 423 GLN B CG  1 
ATOM   9424  C  CD  . GLN B 1 423 ? 225.007 219.827 217.413 1.00 84.83  ? 423 GLN B CD  1 
ATOM   9425  O  OE1 . GLN B 1 423 ? 224.488 218.745 217.675 1.00 84.46  ? 423 GLN B OE1 1 
ATOM   9426  N  NE2 . GLN B 1 423 ? 226.108 219.933 216.683 1.00 87.73  ? 423 GLN B NE2 1 
ATOM   9427  N  N   . ASP B 1 424 ? 220.233 221.731 216.878 1.00 87.65  ? 424 ASP B N   1 
ATOM   9428  C  CA  . ASP B 1 424 ? 218.963 221.802 217.583 1.00 91.02  ? 424 ASP B CA  1 
ATOM   9429  C  C   . ASP B 1 424 ? 218.242 220.466 217.529 1.00 92.63  ? 424 ASP B C   1 
ATOM   9430  O  O   . ASP B 1 424 ? 217.702 220.001 218.539 1.00 96.96  ? 424 ASP B O   1 
ATOM   9431  C  CB  . ASP B 1 424 ? 218.092 222.904 216.983 1.00 91.00  ? 424 ASP B CB  1 
ATOM   9432  C  CG  . ASP B 1 424 ? 218.736 224.268 217.076 1.00 93.48  ? 424 ASP B CG  1 
ATOM   9433  O  OD1 . ASP B 1 424 ? 219.981 224.335 217.140 1.00 91.76  ? 424 ASP B OD1 1 
ATOM   9434  O  OD2 . ASP B 1 424 ? 217.999 225.276 217.084 1.00 100.69 ? 424 ASP B OD2 1 
ATOM   9435  N  N   . VAL B 1 425 ? 218.233 219.828 216.360 1.00 88.37  ? 425 VAL B N   1 
ATOM   9436  C  CA  . VAL B 1 425 ? 217.590 218.528 216.233 1.00 90.43  ? 425 VAL B CA  1 
ATOM   9437  C  C   . VAL B 1 425 ? 218.323 217.492 217.073 1.00 91.83  ? 425 VAL B C   1 
ATOM   9438  O  O   . VAL B 1 425 ? 217.703 216.700 217.791 1.00 93.05  ? 425 VAL B O   1 
ATOM   9439  C  CB  . VAL B 1 425 ? 217.520 218.105 214.756 1.00 90.86  ? 425 VAL B CB  1 
ATOM   9440  C  CG1 . VAL B 1 425 ? 216.569 216.932 214.585 1.00 90.65  ? 425 VAL B CG1 1 
ATOM   9441  C  CG2 . VAL B 1 425 ? 217.101 219.276 213.886 1.00 89.51  ? 425 VAL B CG2 1 
ATOM   9442  N  N   . ILE B 1 426 ? 219.655 217.482 216.997 1.00 91.85  ? 426 ILE B N   1 
ATOM   9443  C  CA  . ILE B 1 426 ? 220.414 216.458 217.711 1.00 91.48  ? 426 ILE B CA  1 
ATOM   9444  C  C   . ILE B 1 426 ? 220.197 216.587 219.212 1.00 94.67  ? 426 ILE B C   1 
ATOM   9445  O  O   . ILE B 1 426 ? 219.989 215.589 219.912 1.00 93.10  ? 426 ILE B O   1 
ATOM   9446  C  CB  . ILE B 1 426 ? 221.908 216.533 217.343 1.00 92.14  ? 426 ILE B CB  1 
ATOM   9447  C  CG1 . ILE B 1 426 ? 222.203 215.648 216.135 1.00 93.27  ? 426 ILE B CG1 1 
ATOM   9448  C  CG2 . ILE B 1 426 ? 222.770 216.084 218.508 1.00 89.05  ? 426 ILE B CG2 1 
ATOM   9449  C  CD1 . ILE B 1 426 ? 223.635 215.733 215.654 1.00 91.01  ? 426 ILE B CD1 1 
ATOM   9450  N  N   . ASP B 1 427 ? 220.221 217.817 219.728 1.00 97.80  ? 427 ASP B N   1 
ATOM   9451  C  CA  . ASP B 1 427 ? 220.071 218.023 221.164 1.00 96.58  ? 427 ASP B CA  1 
ATOM   9452  C  C   . ASP B 1 427 ? 218.634 217.798 221.617 1.00 96.17  ? 427 ASP B C   1 
ATOM   9453  O  O   . ASP B 1 427 ? 218.400 217.259 222.705 1.00 96.53  ? 427 ASP B O   1 
ATOM   9454  C  CB  . ASP B 1 427 ? 220.542 219.426 221.541 1.00 93.39  ? 427 ASP B CB  1 
ATOM   9455  C  CG  . ASP B 1 427 ? 222.044 219.507 221.712 1.00 95.99  ? 427 ASP B CG  1 
ATOM   9456  O  OD1 . ASP B 1 427 ? 222.692 218.441 221.784 1.00 98.13  ? 427 ASP B OD1 1 
ATOM   9457  O  OD2 . ASP B 1 427 ? 222.578 220.634 221.773 1.00 96.72  ? 427 ASP B OD2 1 
ATOM   9458  N  N   . SER B 1 428 ? 217.659 218.196 220.804 1.00 94.82  ? 428 SER B N   1 
ATOM   9459  C  CA  . SER B 1 428 ? 216.266 218.083 221.203 1.00 92.41  ? 428 SER B CA  1 
ATOM   9460  C  C   . SER B 1 428 ? 215.614 216.776 220.775 1.00 94.90  ? 428 SER B C   1 
ATOM   9461  O  O   . SER B 1 428 ? 214.568 216.418 221.327 1.00 95.63  ? 428 SER B O   1 
ATOM   9462  C  CB  . SER B 1 428 ? 215.459 219.252 220.638 1.00 93.86  ? 428 SER B CB  1 
ATOM   9463  O  OG  . SER B 1 428 ? 215.652 219.362 219.242 1.00 96.13  ? 428 SER B OG  1 
ATOM   9464  N  N   . LEU B 1 429 ? 216.192 216.056 219.804 1.00 95.94  ? 429 LEU B N   1 
ATOM   9465  C  CA  . LEU B 1 429 ? 215.562 214.837 219.310 1.00 92.95  ? 429 LEU B CA  1 
ATOM   9466  C  C   . LEU B 1 429 ? 216.542 213.715 218.986 1.00 90.37  ? 429 LEU B C   1 
ATOM   9467  O  O   . LEU B 1 429 ? 216.147 212.750 218.323 1.00 87.57  ? 429 LEU B O   1 
ATOM   9468  C  CB  . LEU B 1 429 ? 214.714 215.138 218.073 1.00 89.06  ? 429 LEU B CB  1 
ATOM   9469  C  CG  . LEU B 1 429 ? 213.369 215.807 218.340 1.00 88.15  ? 429 LEU B CG  1 
ATOM   9470  C  CD1 . LEU B 1 429 ? 212.640 216.073 217.037 1.00 88.94  ? 429 LEU B CD1 1 
ATOM   9471  C  CD2 . LEU B 1 429 ? 212.531 214.937 219.255 1.00 86.46  ? 429 LEU B CD2 1 
ATOM   9472  N  N   . GLY B 1 430 ? 217.794 213.800 219.410 1.00 89.39  ? 430 GLY B N   1 
ATOM   9473  C  CA  . GLY B 1 430 ? 218.728 212.719 219.170 1.00 88.10  ? 430 GLY B CA  1 
ATOM   9474  C  C   . GLY B 1 430 ? 219.098 212.614 217.700 1.00 88.24  ? 430 GLY B C   1 
ATOM   9475  O  O   . GLY B 1 430 ? 218.794 213.481 216.882 1.00 90.10  ? 430 GLY B O   1 
ATOM   9476  N  N   . TYR B 1 431 ? 219.780 211.517 217.367 1.00 79.46  ? 431 TYR B N   1 
ATOM   9477  C  CA  . TYR B 1 431 ? 220.187 211.300 215.983 1.00 74.14  ? 431 TYR B CA  1 
ATOM   9478  C  C   . TYR B 1 431 ? 219.043 210.784 215.126 1.00 73.49  ? 431 TYR B C   1 
ATOM   9479  O  O   . TYR B 1 431 ? 218.981 211.086 213.926 1.00 75.33  ? 431 TYR B O   1 
ATOM   9480  C  CB  . TYR B 1 431 ? 221.355 210.321 215.909 1.00 69.05  ? 431 TYR B CB  1 
ATOM   9481  C  CG  . TYR B 1 431 ? 222.626 210.828 216.531 1.00 72.37  ? 431 TYR B CG  1 
ATOM   9482  C  CD1 . TYR B 1 431 ? 222.687 212.081 217.107 1.00 78.28  ? 431 TYR B CD1 1 
ATOM   9483  C  CD2 . TYR B 1 431 ? 223.771 210.057 216.529 1.00 76.30  ? 431 TYR B CD2 1 
ATOM   9484  C  CE1 . TYR B 1 431 ? 223.843 212.545 217.675 1.00 82.97  ? 431 TYR B CE1 1 
ATOM   9485  C  CE2 . TYR B 1 431 ? 224.937 210.511 217.093 1.00 82.28  ? 431 TYR B CE2 1 
ATOM   9486  C  CZ  . TYR B 1 431 ? 224.968 211.758 217.663 1.00 85.01  ? 431 TYR B CZ  1 
ATOM   9487  O  OH  . TYR B 1 431 ? 226.127 212.227 218.230 1.00 87.90  ? 431 TYR B OH  1 
ATOM   9488  N  N   . ALA B 1 432 ? 218.133 210.016 215.723 1.00 71.70  ? 432 ALA B N   1 
ATOM   9489  C  CA  . ALA B 1 432 ? 217.095 209.335 214.964 1.00 75.12  ? 432 ALA B CA  1 
ATOM   9490  C  C   . ALA B 1 432 ? 216.160 210.295 214.255 1.00 75.98  ? 432 ALA B C   1 
ATOM   9491  O  O   . ALA B 1 432 ? 215.259 209.842 213.543 1.00 78.51  ? 432 ALA B O   1 
ATOM   9492  C  CB  . ALA B 1 432 ? 216.293 208.417 215.888 1.00 76.25  ? 432 ALA B CB  1 
ATOM   9493  N  N   . TRP B 1 433 ? 216.338 211.597 214.435 1.00 75.45  ? 433 TRP B N   1 
ATOM   9494  C  CA  . TRP B 1 433 ? 215.499 212.568 213.757 1.00 80.33  ? 433 TRP B CA  1 
ATOM   9495  C  C   . TRP B 1 433 ? 216.372 213.570 213.021 1.00 80.33  ? 433 TRP B C   1 
ATOM   9496  O  O   . TRP B 1 433 ? 215.942 214.180 212.038 1.00 84.75  ? 433 TRP B O   1 
ATOM   9497  C  CB  . TRP B 1 433 ? 214.573 213.240 214.763 1.00 86.23  ? 433 TRP B CB  1 
ATOM   9498  C  CG  . TRP B 1 433 ? 213.424 212.363 215.102 1.00 85.78  ? 433 TRP B CG  1 
ATOM   9499  C  CD1 . TRP B 1 433 ? 213.470 211.172 215.763 1.00 83.23  ? 433 TRP B CD1 1 
ATOM   9500  C  CD2 . TRP B 1 433 ? 212.049 212.605 214.804 1.00 89.89  ? 433 TRP B CD2 1 
ATOM   9501  N  NE1 . TRP B 1 433 ? 212.208 210.653 215.887 1.00 86.29  ? 433 TRP B NE1 1 
ATOM   9502  C  CE2 . TRP B 1 433 ? 211.316 211.516 215.310 1.00 90.75  ? 433 TRP B CE2 1 
ATOM   9503  C  CE3 . TRP B 1 433 ? 211.365 213.638 214.160 1.00 97.81  ? 433 TRP B CE3 1 
ATOM   9504  C  CZ2 . TRP B 1 433 ? 209.934 211.429 215.190 1.00 97.10  ? 433 TRP B CZ2 1 
ATOM   9505  C  CZ3 . TRP B 1 433 ? 209.996 213.550 214.041 1.00 103.48 ? 433 TRP B CZ3 1 
ATOM   9506  C  CH2 . TRP B 1 433 ? 209.294 212.453 214.553 1.00 103.61 ? 433 TRP B CH2 1 
ATOM   9507  N  N   . ALA B 1 434 ? 217.614 213.724 213.469 1.00 75.62  ? 434 ALA B N   1 
ATOM   9508  C  CA  . ALA B 1 434 ? 218.576 214.467 212.670 1.00 76.32  ? 434 ALA B CA  1 
ATOM   9509  C  C   . ALA B 1 434 ? 218.769 213.798 211.317 1.00 80.08  ? 434 ALA B C   1 
ATOM   9510  O  O   . ALA B 1 434 ? 218.835 214.471 210.280 1.00 80.18  ? 434 ALA B O   1 
ATOM   9511  C  CB  . ALA B 1 434 ? 219.906 214.581 213.414 1.00 78.19  ? 434 ALA B CB  1 
ATOM   9512  N  N   . ASP B 1 435 ? 218.831 212.465 211.302 1.00 78.96  ? 435 ASP B N   1 
ATOM   9513  C  CA  . ASP B 1 435 ? 218.975 211.769 210.029 1.00 71.47  ? 435 ASP B CA  1 
ATOM   9514  C  C   . ASP B 1 435 ? 217.695 211.817 209.204 1.00 67.96  ? 435 ASP B C   1 
ATOM   9515  O  O   . ASP B 1 435 ? 217.761 211.840 207.972 1.00 70.96  ? 435 ASP B O   1 
ATOM   9516  C  CB  . ASP B 1 435 ? 219.434 210.337 210.265 1.00 69.99  ? 435 ASP B CB  1 
ATOM   9517  C  CG  . ASP B 1 435 ? 220.810 210.274 210.893 1.00 75.22  ? 435 ASP B CG  1 
ATOM   9518  O  OD1 . ASP B 1 435 ? 221.807 210.434 210.163 1.00 73.66  ? 435 ASP B OD1 1 
ATOM   9519  O  OD2 . ASP B 1 435 ? 220.899 210.063 212.120 1.00 79.20  ? 435 ASP B OD2 1 
ATOM   9520  N  N   . GLN B 1 436 ? 216.528 211.859 209.846 1.00 67.84  ? 436 GLN B N   1 
ATOM   9521  C  CA  . GLN B 1 436 ? 215.296 212.078 209.095 1.00 68.75  ? 436 GLN B CA  1 
ATOM   9522  C  C   . GLN B 1 436 ? 215.294 213.447 208.429 1.00 72.77  ? 436 GLN B C   1 
ATOM   9523  O  O   . GLN B 1 436 ? 214.883 213.588 207.268 1.00 77.31  ? 436 GLN B O   1 
ATOM   9524  C  CB  . GLN B 1 436 ? 214.085 211.928 210.010 1.00 67.59  ? 436 GLN B CB  1 
ATOM   9525  C  CG  . GLN B 1 436 ? 213.608 210.500 210.164 1.00 73.50  ? 436 GLN B CG  1 
ATOM   9526  C  CD  . GLN B 1 436 ? 212.602 210.114 209.104 1.00 77.31  ? 436 GLN B CD  1 
ATOM   9527  O  OE1 . GLN B 1 436 ? 212.500 210.764 208.066 1.00 76.57  ? 436 GLN B OE1 1 
ATOM   9528  N  NE2 . GLN B 1 436 ? 211.850 209.052 209.360 1.00 76.47  ? 436 GLN B NE2 1 
ATOM   9529  N  N   . ALA B 1 437 ? 215.752 214.469 209.151 1.00 76.28  ? 437 ALA B N   1 
ATOM   9530  C  CA  . ALA B 1 437 ? 215.869 215.796 208.560 1.00 77.77  ? 437 ALA B CA  1 
ATOM   9531  C  C   . ALA B 1 437 ? 216.852 215.791 207.398 1.00 75.04  ? 437 ALA B C   1 
ATOM   9532  O  O   . ALA B 1 437 ? 216.615 216.438 206.370 1.00 79.08  ? 437 ALA B O   1 
ATOM   9533  C  CB  . ALA B 1 437 ? 216.296 216.808 209.622 1.00 80.32  ? 437 ALA B CB  1 
ATOM   9534  N  N   . LEU B 1 438 ? 217.962 215.067 207.540 1.00 71.50  ? 438 LEU B N   1 
ATOM   9535  C  CA  . LEU B 1 438 ? 218.910 214.965 206.435 1.00 71.36  ? 438 LEU B CA  1 
ATOM   9536  C  C   . LEU B 1 438 ? 218.277 214.290 205.223 1.00 76.53  ? 438 LEU B C   1 
ATOM   9537  O  O   . LEU B 1 438 ? 218.527 214.689 204.078 1.00 77.12  ? 438 LEU B O   1 
ATOM   9538  C  CB  . LEU B 1 438 ? 220.160 214.213 206.878 1.00 68.25  ? 438 LEU B CB  1 
ATOM   9539  C  CG  . LEU B 1 438 ? 221.161 215.026 207.690 1.00 66.45  ? 438 LEU B CG  1 
ATOM   9540  C  CD1 . LEU B 1 438 ? 222.088 214.108 208.455 1.00 67.03  ? 438 LEU B CD1 1 
ATOM   9541  C  CD2 . LEU B 1 438 ? 221.951 215.931 206.775 1.00 64.69  ? 438 LEU B CD2 1 
ATOM   9542  N  N   . LEU B 1 439 ? 217.461 213.259 205.453 1.00 77.28  ? 439 LEU B N   1 
ATOM   9543  C  CA  . LEU B 1 439 ? 216.771 212.597 204.348 1.00 70.48  ? 439 LEU B CA  1 
ATOM   9544  C  C   . LEU B 1 439 ? 215.826 213.553 203.632 1.00 72.76  ? 439 LEU B C   1 
ATOM   9545  O  O   . LEU B 1 439 ? 215.766 213.571 202.396 1.00 76.90  ? 439 LEU B O   1 
ATOM   9546  C  CB  . LEU B 1 439 ? 216.006 211.380 204.863 1.00 71.03  ? 439 LEU B CB  1 
ATOM   9547  C  CG  . LEU B 1 439 ? 215.422 210.436 203.812 1.00 76.80  ? 439 LEU B CG  1 
ATOM   9548  C  CD1 . LEU B 1 439 ? 216.470 210.009 202.815 1.00 76.93  ? 439 LEU B CD1 1 
ATOM   9549  C  CD2 . LEU B 1 439 ? 214.793 209.224 204.478 1.00 74.15  ? 439 LEU B CD2 1 
ATOM   9550  N  N   . GLU B 1 440 ? 215.074 214.346 204.394 1.00 70.17  ? 440 GLU B N   1 
ATOM   9551  C  CA  . GLU B 1 440 ? 214.167 215.309 203.777 1.00 72.51  ? 440 GLU B CA  1 
ATOM   9552  C  C   . GLU B 1 440 ? 214.960 216.330 202.965 1.00 74.52  ? 440 GLU B C   1 
ATOM   9553  O  O   . GLU B 1 440 ? 214.578 216.690 201.840 1.00 76.18  ? 440 GLU B O   1 
ATOM   9554  C  CB  . GLU B 1 440 ? 213.325 215.978 204.870 1.00 76.84  ? 440 GLU B CB  1 
ATOM   9555  C  CG  . GLU B 1 440 ? 212.979 217.474 204.755 1.00 87.95  ? 440 GLU B CG  1 
ATOM   9556  C  CD  . GLU B 1 440 ? 212.370 217.923 203.428 1.00 90.71  ? 440 GLU B CD  1 
ATOM   9557  O  OE1 . GLU B 1 440 ? 212.064 217.079 202.558 1.00 82.73  ? 440 GLU B OE1 1 
ATOM   9558  O  OE2 . GLU B 1 440 ? 212.196 219.148 203.259 1.00 94.29  ? 440 GLU B OE2 1 
ATOM   9559  N  N   . VAL B 1 441 ? 216.095 216.773 203.505 1.00 73.00  ? 441 VAL B N   1 
ATOM   9560  C  CA  . VAL B 1 441 ? 216.956 217.703 202.783 1.00 74.28  ? 441 VAL B CA  1 
ATOM   9561  C  C   . VAL B 1 441 ? 217.396 217.100 201.456 1.00 71.62  ? 441 VAL B C   1 
ATOM   9562  O  O   . VAL B 1 441 ? 217.330 217.750 200.407 1.00 73.11  ? 441 VAL B O   1 
ATOM   9563  C  CB  . VAL B 1 441 ? 218.162 218.091 203.658 1.00 78.81  ? 441 VAL B CB  1 
ATOM   9564  C  CG1 . VAL B 1 441 ? 219.290 218.639 202.812 1.00 77.08  ? 441 VAL B CG1 1 
ATOM   9565  C  CG2 . VAL B 1 441 ? 217.748 219.103 204.710 1.00 76.12  ? 441 VAL B CG2 1 
ATOM   9566  N  N   . VAL B 1 442 ? 217.848 215.848 201.481 1.00 72.66  ? 442 VAL B N   1 
ATOM   9567  C  CA  . VAL B 1 442 ? 218.342 215.222 200.259 1.00 72.76  ? 442 VAL B CA  1 
ATOM   9568  C  C   . VAL B 1 442 ? 217.218 215.073 199.245 1.00 76.02  ? 442 VAL B C   1 
ATOM   9569  O  O   . VAL B 1 442 ? 217.427 215.245 198.037 1.00 77.68  ? 442 VAL B O   1 
ATOM   9570  C  CB  . VAL B 1 442 ? 219.007 213.873 200.580 1.00 72.32  ? 442 VAL B CB  1 
ATOM   9571  C  CG1 . VAL B 1 442 ? 219.281 213.099 199.311 1.00 65.67  ? 442 VAL B CG1 1 
ATOM   9572  C  CG2 . VAL B 1 442 ? 220.289 214.096 201.347 1.00 71.18  ? 442 VAL B CG2 1 
ATOM   9573  N  N   . ASN B 1 443 ? 216.010 214.749 199.712 1.00 77.51  ? 443 ASN B N   1 
ATOM   9574  C  CA  . ASN B 1 443 ? 214.873 214.667 198.798 1.00 74.51  ? 443 ASN B CA  1 
ATOM   9575  C  C   . ASN B 1 443 ? 214.633 216.004 198.110 1.00 74.54  ? 443 ASN B C   1 
ATOM   9576  O  O   . ASN B 1 443 ? 214.414 216.058 196.891 1.00 74.63  ? 443 ASN B O   1 
ATOM   9577  C  CB  . ASN B 1 443 ? 213.619 214.227 199.552 1.00 73.68  ? 443 ASN B CB  1 
ATOM   9578  C  CG  . ASN B 1 443 ? 213.585 212.738 199.807 1.00 74.70  ? 443 ASN B CG  1 
ATOM   9579  O  OD1 . ASN B 1 443 ? 214.270 211.966 199.139 1.00 76.43  ? 443 ASN B OD1 1 
ATOM   9580  N  ND2 . ASN B 1 443 ? 212.784 212.324 200.778 1.00 74.69  ? 443 ASN B ND2 1 
ATOM   9581  N  N   . ARG B 1 444 ? 214.691 217.095 198.875 1.00 74.07  ? 444 ARG B N   1 
ATOM   9582  C  CA  . ARG B 1 444 ? 214.484 218.414 198.286 1.00 74.29  ? 444 ARG B CA  1 
ATOM   9583  C  C   . ARG B 1 444 ? 215.584 218.765 197.287 1.00 75.26  ? 444 ARG B C   1 
ATOM   9584  O  O   . ARG B 1 444 ? 215.307 219.359 196.240 1.00 74.63  ? 444 ARG B O   1 
ATOM   9585  C  CB  . ARG B 1 444 ? 214.389 219.468 199.385 1.00 77.40  ? 444 ARG B CB  1 
ATOM   9586  C  CG  . ARG B 1 444 ? 213.100 219.392 200.177 1.00 80.39  ? 444 ARG B CG  1 
ATOM   9587  C  CD  . ARG B 1 444 ? 212.130 220.481 199.764 1.00 80.79  ? 444 ARG B CD  1 
ATOM   9588  N  NE  . ARG B 1 444 ? 212.332 221.709 200.522 1.00 80.21  ? 444 ARG B NE  1 
ATOM   9589  C  CZ  . ARG B 1 444 ? 211.823 221.937 201.725 1.00 83.13  ? 444 ARG B CZ  1 
ATOM   9590  N  NH1 . ARG B 1 444 ? 211.078 221.035 202.341 1.00 87.01  ? 444 ARG B NH1 1 
ATOM   9591  N  NH2 . ARG B 1 444 ? 212.070 223.097 202.325 1.00 86.92  ? 444 ARG B NH2 1 
ATOM   9592  N  N   . PHE B 1 445 ? 216.837 218.425 197.596 1.00 77.12  ? 445 PHE B N   1 
ATOM   9593  C  CA  . PHE B 1 445 ? 217.915 218.644 196.629 1.00 75.24  ? 445 PHE B CA  1 
ATOM   9594  C  C   . PHE B 1 445 ? 217.698 217.853 195.349 1.00 76.03  ? 445 PHE B C   1 
ATOM   9595  O  O   . PHE B 1 445 ? 217.914 218.374 194.249 1.00 78.15  ? 445 PHE B O   1 
ATOM   9596  C  CB  . PHE B 1 445 ? 219.287 218.306 197.222 1.00 73.44  ? 445 PHE B CB  1 
ATOM   9597  C  CG  . PHE B 1 445 ? 219.762 219.249 198.296 1.00 75.35  ? 445 PHE B CG  1 
ATOM   9598  C  CD1 . PHE B 1 445 ? 218.893 219.847 199.183 1.00 77.09  ? 445 PHE B CD1 1 
ATOM   9599  C  CD2 . PHE B 1 445 ? 221.116 219.509 198.423 1.00 75.57  ? 445 PHE B CD2 1 
ATOM   9600  C  CE1 . PHE B 1 445 ? 219.356 220.708 200.154 1.00 77.36  ? 445 PHE B CE1 1 
ATOM   9601  C  CE2 . PHE B 1 445 ? 221.586 220.360 199.396 1.00 76.38  ? 445 PHE B CE2 1 
ATOM   9602  C  CZ  . PHE B 1 445 ? 220.704 220.958 200.266 1.00 77.66  ? 445 PHE B CZ  1 
ATOM   9603  N  N   . ARG B 1 446 ? 217.284 216.592 195.465 1.00 75.16  ? 446 ARG B N   1 
ATOM   9604  C  CA  . ARG B 1 446 ? 217.142 215.769 194.269 1.00 71.04  ? 446 ARG B CA  1 
ATOM   9605  C  C   . ARG B 1 446 ? 215.976 216.233 193.413 1.00 73.90  ? 446 ARG B C   1 
ATOM   9606  O  O   . ARG B 1 446 ? 216.021 216.122 192.183 1.00 73.91  ? 446 ARG B O   1 
ATOM   9607  C  CB  . ARG B 1 446 ? 216.964 214.304 194.645 1.00 69.35  ? 446 ARG B CB  1 
ATOM   9608  C  CG  . ARG B 1 446 ? 218.253 213.528 194.721 1.00 71.00  ? 446 ARG B CG  1 
ATOM   9609  C  CD  . ARG B 1 446 ? 217.969 212.051 194.642 1.00 70.71  ? 446 ARG B CD  1 
ATOM   9610  N  NE  . ARG B 1 446 ? 217.249 211.597 195.823 1.00 72.20  ? 446 ARG B NE  1 
ATOM   9611  C  CZ  . ARG B 1 446 ? 217.665 210.626 196.620 1.00 67.81  ? 446 ARG B CZ  1 
ATOM   9612  N  NH1 . ARG B 1 446 ? 218.795 209.981 196.389 1.00 63.09  ? 446 ARG B NH1 1 
ATOM   9613  N  NH2 . ARG B 1 446 ? 216.933 210.300 197.679 1.00 69.32  ? 446 ARG B NH2 1 
ATOM   9614  N  N   . GLU B 1 447 ? 214.926 216.766 194.042 1.00 78.88  ? 447 GLU B N   1 
ATOM   9615  C  CA  . GLU B 1 447 ? 213.722 217.104 193.292 1.00 78.82  ? 447 GLU B CA  1 
ATOM   9616  C  C   . GLU B 1 447 ? 213.993 218.148 192.214 1.00 75.65  ? 447 GLU B C   1 
ATOM   9617  O  O   . GLU B 1 447 ? 213.285 218.188 191.202 1.00 76.09  ? 447 GLU B O   1 
ATOM   9618  C  CB  . GLU B 1 447 ? 212.623 217.542 194.270 1.00 79.92  ? 447 GLU B CB  1 
ATOM   9619  C  CG  . GLU B 1 447 ? 211.497 218.423 193.730 1.00 78.44  ? 447 GLU B CG  1 
ATOM   9620  C  CD  . GLU B 1 447 ? 211.902 219.872 193.561 1.00 84.52  ? 447 GLU B CD  1 
ATOM   9621  O  OE1 . GLU B 1 447 ? 212.883 220.289 194.209 1.00 83.75  ? 447 GLU B OE1 1 
ATOM   9622  O  OE2 . GLU B 1 447 ? 211.239 220.591 192.784 1.00 86.57  ? 447 GLU B OE2 1 
ATOM   9623  N  N   . LYS B 1 448 ? 215.015 218.985 192.390 1.00 72.81  ? 448 LYS B N   1 
ATOM   9624  C  CA  . LYS B 1 448 ? 215.357 219.987 191.388 1.00 73.92  ? 448 LYS B CA  1 
ATOM   9625  C  C   . LYS B 1 448 ? 216.711 219.747 190.741 1.00 70.81  ? 448 LYS B C   1 
ATOM   9626  O  O   . LYS B 1 448 ? 217.213 220.630 190.042 1.00 72.19  ? 448 LYS B O   1 
ATOM   9627  C  CB  . LYS B 1 448 ? 215.319 221.392 191.994 1.00 79.55  ? 448 LYS B CB  1 
ATOM   9628  C  CG  . LYS B 1 448 ? 213.970 222.113 191.877 1.00 82.85  ? 448 LYS B CG  1 
ATOM   9629  C  CD  . LYS B 1 448 ? 213.420 222.308 190.446 1.00 83.60  ? 448 LYS B CD  1 
ATOM   9630  C  CE  . LYS B 1 448 ? 214.484 222.499 189.358 1.00 85.15  ? 448 LYS B CE  1 
ATOM   9631  N  NZ  . LYS B 1 448 ? 215.453 223.588 189.675 1.00 81.80  ? 448 LYS B NZ  1 
ATOM   9632  N  N   . LEU B 1 449 ? 217.312 218.585 190.946 1.00 67.70  ? 449 LEU B N   1 
ATOM   9633  C  CA  . LEU B 1 449 ? 218.599 218.322 190.329 1.00 67.63  ? 449 LEU B CA  1 
ATOM   9634  C  C   . LEU B 1 449 ? 218.440 218.175 188.825 1.00 70.39  ? 449 LEU B C   1 
ATOM   9635  O  O   . LEU B 1 449 ? 217.456 217.616 188.335 1.00 75.80  ? 449 LEU B O   1 
ATOM   9636  C  CB  . LEU B 1 449 ? 219.234 217.062 190.906 1.00 72.05  ? 449 LEU B CB  1 
ATOM   9637  C  CG  . LEU B 1 449 ? 220.679 216.828 190.467 1.00 68.93  ? 449 LEU B CG  1 
ATOM   9638  C  CD1 . LEU B 1 449 ? 221.630 217.490 191.439 1.00 62.94  ? 449 LEU B CD1 1 
ATOM   9639  C  CD2 . LEU B 1 449 ? 220.980 215.349 190.346 1.00 67.75  ? 449 LEU B CD2 1 
ATOM   9640  N  N   . LYS B 1 450 ? 219.396 218.677 188.110 1.00 71.23  ? 450 LYS B N   1 
ATOM   9641  C  CA  . LYS B 1 450 ? 219.495 218.571 186.669 1.00 72.33  ? 450 LYS B CA  1 
ATOM   9642  C  C   . LYS B 1 450 ? 220.432 217.424 186.315 1.00 72.67  ? 450 LYS B C   1 
ATOM   9643  O  O   . LYS B 1 450 ? 221.362 217.122 187.065 1.00 73.36  ? 450 LYS B O   1 
ATOM   9644  C  CB  . LYS B 1 450 ? 220.006 219.897 186.111 1.00 72.54  ? 450 LYS B CB  1 
ATOM   9645  C  CG  . LYS B 1 450 ? 219.654 220.216 184.673 1.00 75.29  ? 450 LYS B CG  1 
ATOM   9646  C  CD  . LYS B 1 450 ? 220.060 221.640 184.320 1.00 83.63  ? 450 LYS B CD  1 
ATOM   9647  C  CE  . LYS B 1 450 ? 219.795 222.608 185.473 1.00 86.68  ? 450 LYS B CE  1 
ATOM   9648  N  NZ  . LYS B 1 450 ? 218.370 222.622 185.919 1.00 89.59  ? 450 LYS B NZ  1 
ATOM   9649  N  N   . PRO B 1 451 ? 220.211 216.735 185.201 1.00 70.85  ? 451 PRO B N   1 
ATOM   9650  C  CA  . PRO B 1 451 ? 221.137 215.665 184.819 1.00 67.10  ? 451 PRO B CA  1 
ATOM   9651  C  C   . PRO B 1 451 ? 222.504 216.230 184.484 1.00 66.27  ? 451 PRO B C   1 
ATOM   9652  O  O   . PRO B 1 451 ? 222.648 217.395 184.113 1.00 69.71  ? 451 PRO B O   1 
ATOM   9653  C  CB  . PRO B 1 451 ? 220.484 215.015 183.595 1.00 69.98  ? 451 PRO B CB  1 
ATOM   9654  C  CG  . PRO B 1 451 ? 219.170 215.672 183.408 1.00 72.87  ? 451 PRO B CG  1 
ATOM   9655  C  CD  . PRO B 1 451 ? 219.080 216.878 184.271 1.00 72.59  ? 451 PRO B CD  1 
ATOM   9656  N  N   . ASP B 1 452 ? 223.515 215.371 184.624 1.00 61.06  ? 452 ASP B N   1 
ATOM   9657  C  CA  . ASP B 1 452 ? 224.951 215.631 184.578 1.00 64.53  ? 452 ASP B CA  1 
ATOM   9658  C  C   . ASP B 1 452 ? 225.398 216.242 185.915 1.00 69.20  ? 452 ASP B C   1 
ATOM   9659  O  O   . ASP B 1 452 ? 226.569 216.123 186.265 1.00 67.81  ? 452 ASP B O   1 
ATOM   9660  C  CB  . ASP B 1 452 ? 225.337 216.535 183.377 1.00 70.58  ? 452 ASP B CB  1 
ATOM   9661  C  CG  . ASP B 1 452 ? 226.636 217.354 183.542 1.00 76.68  ? 452 ASP B CG  1 
ATOM   9662  O  OD1 . ASP B 1 452 ? 227.542 217.051 184.336 1.00 75.44  ? 452 ASP B OD1 1 
ATOM   9663  O  OD2 . ASP B 1 452 ? 226.742 218.371 182.825 1.00 81.13  ? 452 ASP B OD2 1 
ATOM   9664  N  N   . GLN B 1 453 ? 224.476 216.701 186.758 1.00 70.73  ? 453 GLN B N   1 
ATOM   9665  C  CA  . GLN B 1 453 ? 224.819 217.208 188.081 1.00 62.25  ? 453 GLN B CA  1 
ATOM   9666  C  C   . GLN B 1 453 ? 224.932 216.029 189.037 1.00 58.87  ? 453 GLN B C   1 
ATOM   9667  O  O   . GLN B 1 453 ? 224.003 215.225 189.147 1.00 64.22  ? 453 GLN B O   1 
ATOM   9668  C  CB  . GLN B 1 453 ? 223.771 218.203 188.569 1.00 60.84  ? 453 GLN B CB  1 
ATOM   9669  C  CG  . GLN B 1 453 ? 223.756 219.491 187.793 1.00 63.00  ? 453 GLN B CG  1 
ATOM   9670  C  CD  . GLN B 1 453 ? 222.890 220.541 188.437 1.00 71.06  ? 453 GLN B CD  1 
ATOM   9671  O  OE1 . GLN B 1 453 ? 222.364 220.336 189.528 1.00 74.40  ? 453 GLN B OE1 1 
ATOM   9672  N  NE2 . GLN B 1 453 ? 222.729 221.671 187.765 1.00 71.09  ? 453 GLN B NE2 1 
ATOM   9673  N  N   . TYR B 1 454 ? 226.063 215.925 189.720 1.00 50.42  ? 454 TYR B N   1 
ATOM   9674  C  CA  . TYR B 1 454 ? 226.369 214.762 190.541 1.00 49.33  ? 454 TYR B CA  1 
ATOM   9675  C  C   . TYR B 1 454 ? 226.256 215.119 192.014 1.00 50.78  ? 454 TYR B C   1 
ATOM   9676  O  O   . TYR B 1 454 ? 226.935 216.037 192.483 1.00 54.43  ? 454 TYR B O   1 
ATOM   9677  C  CB  . TYR B 1 454 ? 227.769 214.263 190.227 1.00 50.43  ? 454 TYR B CB  1 
ATOM   9678  C  CG  . TYR B 1 454 ? 228.307 213.259 191.203 1.00 54.76  ? 454 TYR B CG  1 
ATOM   9679  C  CD1 . TYR B 1 454 ? 227.840 211.959 191.220 1.00 56.19  ? 454 TYR B CD1 1 
ATOM   9680  C  CD2 . TYR B 1 454 ? 229.306 213.607 192.094 1.00 60.15  ? 454 TYR B CD2 1 
ATOM   9681  C  CE1 . TYR B 1 454 ? 228.346 211.035 192.105 1.00 61.35  ? 454 TYR B CE1 1 
ATOM   9682  C  CE2 . TYR B 1 454 ? 229.816 212.694 192.983 1.00 62.05  ? 454 TYR B CE2 1 
ATOM   9683  C  CZ  . TYR B 1 454 ? 229.332 211.410 192.987 1.00 65.96  ? 454 TYR B CZ  1 
ATOM   9684  O  OH  . TYR B 1 454 ? 229.845 210.500 193.881 1.00 69.98  ? 454 TYR B OH  1 
ATOM   9685  N  N   . LEU B 1 455 ? 225.419 214.387 192.739 1.00 50.69  ? 455 LEU B N   1 
ATOM   9686  C  CA  . LEU B 1 455 ? 225.208 214.598 194.163 1.00 51.83  ? 455 LEU B CA  1 
ATOM   9687  C  C   . LEU B 1 455 ? 225.855 213.466 194.941 1.00 55.59  ? 455 LEU B C   1 
ATOM   9688  O  O   . LEU B 1 455 ? 225.608 212.292 194.649 1.00 58.18  ? 455 LEU B O   1 
ATOM   9689  C  CB  . LEU B 1 455 ? 223.719 214.664 194.488 1.00 49.13  ? 455 LEU B CB  1 
ATOM   9690  C  CG  . LEU B 1 455 ? 223.361 215.329 195.807 1.00 43.70  ? 455 LEU B CG  1 
ATOM   9691  C  CD1 . LEU B 1 455 ? 224.278 216.492 196.066 1.00 46.35  ? 455 LEU B CD1 1 
ATOM   9692  C  CD2 . LEU B 1 455 ? 221.932 215.779 195.785 1.00 47.90  ? 455 LEU B CD2 1 
ATOM   9693  N  N   . CYS B 1 456 ? 226.680 213.811 195.927 1.00 52.58  ? 456 CYS B N   1 
ATOM   9694  C  CA  . CYS B 1 456 ? 227.306 212.802 196.762 1.00 52.46  ? 456 CYS B CA  1 
ATOM   9695  C  C   . CYS B 1 456 ? 227.329 213.279 198.204 1.00 52.91  ? 456 CYS B C   1 
ATOM   9696  O  O   . CYS B 1 456 ? 227.296 214.479 198.476 1.00 57.85  ? 456 CYS B O   1 
ATOM   9697  C  CB  . CYS B 1 456 ? 228.722 212.478 196.289 1.00 54.51  ? 456 CYS B CB  1 
ATOM   9698  S  SG  . CYS B 1 456 ? 229.978 213.571 196.905 1.00 58.89  ? 456 CYS B SG  1 
ATOM   9699  N  N   . ARG B 1 457 ? 227.376 212.326 199.124 1.00 51.93  ? 457 ARG B N   1 
ATOM   9700  C  CA  . ARG B 1 457 ? 227.377 212.591 200.559 1.00 51.37  ? 457 ARG B CA  1 
ATOM   9701  C  C   . ARG B 1 457 ? 228.755 212.270 201.113 1.00 56.36  ? 457 ARG B C   1 
ATOM   9702  O  O   . ARG B 1 457 ? 229.181 211.112 201.099 1.00 64.15  ? 457 ARG B O   1 
ATOM   9703  C  CB  . ARG B 1 457 ? 226.305 211.766 201.255 1.00 50.70  ? 457 ARG B CB  1 
ATOM   9704  C  CG  . ARG B 1 457 ? 226.393 211.773 202.754 1.00 53.83  ? 457 ARG B CG  1 
ATOM   9705  C  CD  . ARG B 1 457 ? 225.020 211.659 203.364 1.00 61.61  ? 457 ARG B CD  1 
ATOM   9706  N  NE  . ARG B 1 457 ? 225.047 211.771 204.815 1.00 66.52  ? 457 ARG B NE  1 
ATOM   9707  C  CZ  . ARG B 1 457 ? 223.980 211.652 205.591 1.00 67.54  ? 457 ARG B CZ  1 
ATOM   9708  N  NH1 . ARG B 1 457 ? 222.781 211.424 205.087 1.00 68.79  ? 457 ARG B NH1 1 
ATOM   9709  N  NH2 . ARG B 1 457 ? 224.120 211.765 206.908 1.00 64.04  ? 457 ARG B NH2 1 
ATOM   9710  N  N   . ILE B 1 458 ? 229.445 213.291 201.614 1.00 53.60  ? 458 ILE B N   1 
ATOM   9711  C  CA  . ILE B 1 458 ? 230.803 213.101 202.106 1.00 57.99  ? 458 ILE B CA  1 
ATOM   9712  C  C   . ILE B 1 458 ? 230.789 212.399 203.454 1.00 64.38  ? 458 ILE B C   1 
ATOM   9713  O  O   . ILE B 1 458 ? 231.268 211.268 203.587 1.00 68.14  ? 458 ILE B O   1 
ATOM   9714  C  CB  . ILE B 1 458 ? 231.536 214.450 202.188 1.00 59.15  ? 458 ILE B CB  1 
ATOM   9715  C  CG1 . ILE B 1 458 ? 231.922 214.930 200.796 1.00 57.39  ? 458 ILE B CG1 1 
ATOM   9716  C  CG2 . ILE B 1 458 ? 232.771 214.327 203.052 1.00 62.50  ? 458 ILE B CG2 1 
ATOM   9717  C  CD1 . ILE B 1 458 ? 233.113 214.220 200.230 1.00 63.17  ? 458 ILE B CD1 1 
ATOM   9718  N  N   . GLU B 1 459 ? 230.222 213.051 204.467 1.00 63.05  ? 459 GLU B N   1 
ATOM   9719  C  CA  . GLU B 1 459 ? 230.113 212.441 205.784 1.00 61.99  ? 459 GLU B CA  1 
ATOM   9720  C  C   . GLU B 1 459 ? 229.135 213.249 206.620 1.00 60.95  ? 459 GLU B C   1 
ATOM   9721  O  O   . GLU B 1 459 ? 229.252 214.474 206.705 1.00 60.20  ? 459 GLU B O   1 
ATOM   9722  C  CB  . GLU B 1 459 ? 231.492 212.333 206.462 1.00 61.56  ? 459 GLU B CB  1 
ATOM   9723  C  CG  . GLU B 1 459 ? 232.167 213.625 206.899 1.00 64.17  ? 459 GLU B CG  1 
ATOM   9724  C  CD  . GLU B 1 459 ? 231.657 214.135 208.230 1.00 68.98  ? 459 GLU B CD  1 
ATOM   9725  O  OE1 . GLU B 1 459 ? 231.831 215.336 208.520 1.00 65.55  ? 459 GLU B OE1 1 
ATOM   9726  O  OE2 . GLU B 1 459 ? 231.068 213.331 208.982 1.00 71.44  ? 459 GLU B OE2 1 
ATOM   9727  N  N   . GLY B 1 460 ? 228.156 212.566 207.202 1.00 62.76  ? 460 GLY B N   1 
ATOM   9728  C  CA  . GLY B 1 460 ? 227.221 213.218 208.090 1.00 62.88  ? 460 GLY B CA  1 
ATOM   9729  C  C   . GLY B 1 460 ? 226.468 214.358 207.444 1.00 61.92  ? 460 GLY B C   1 
ATOM   9730  O  O   . GLY B 1 460 ? 225.538 214.153 206.662 1.00 65.02  ? 460 GLY B O   1 
ATOM   9731  N  N   . THR B 1 461 ? 226.865 215.573 207.797 1.00 56.05  ? 461 THR B N   1 
ATOM   9732  C  CA  . THR B 1 461 ? 226.203 216.775 207.314 1.00 56.68  ? 461 THR B CA  1 
ATOM   9733  C  C   . THR B 1 461 ? 226.554 217.096 205.866 1.00 55.25  ? 461 THR B C   1 
ATOM   9734  O  O   . THR B 1 461 ? 225.676 217.461 205.079 1.00 56.18  ? 461 THR B O   1 
ATOM   9735  C  CB  . THR B 1 461 ? 226.576 217.939 208.226 1.00 66.13  ? 461 THR B CB  1 
ATOM   9736  O  OG1 . THR B 1 461 ? 225.750 217.904 209.390 1.00 73.61  ? 461 THR B OG1 1 
ATOM   9737  C  CG2 . THR B 1 461 ? 226.405 219.269 207.524 1.00 68.24  ? 461 THR B CG2 1 
ATOM   9738  N  N   . GLN B 1 462 ? 227.818 216.950 205.494 1.00 52.77  ? 462 GLN B N   1 
ATOM   9739  C  CA  . GLN B 1 462 ? 228.322 217.543 204.266 1.00 50.96  ? 462 GLN B CA  1 
ATOM   9740  C  C   . GLN B 1 462 ? 227.847 216.812 203.015 1.00 52.28  ? 462 GLN B C   1 
ATOM   9741  O  O   . GLN B 1 462 ? 227.598 215.604 203.022 1.00 58.41  ? 462 GLN B O   1 
ATOM   9742  C  CB  . GLN B 1 462 ? 229.841 217.571 204.302 1.00 50.22  ? 462 GLN B CB  1 
ATOM   9743  C  CG  . GLN B 1 462 ? 230.370 218.427 205.422 1.00 52.68  ? 462 GLN B CG  1 
ATOM   9744  C  CD  . GLN B 1 462 ? 231.868 218.428 205.482 1.00 58.93  ? 462 GLN B CD  1 
ATOM   9745  O  OE1 . GLN B 1 462 ? 232.541 218.429 204.458 1.00 57.87  ? 462 GLN B OE1 1 
ATOM   9746  N  NE2 . GLN B 1 462 ? 232.406 218.430 206.691 1.00 64.19  ? 462 GLN B NE2 1 
ATOM   9747  N  N   . PHE B 1 463 ? 227.729 217.575 201.930 1.00 49.29  ? 463 PHE B N   1 
ATOM   9748  C  CA  . PHE B 1 463 ? 227.435 217.057 200.604 1.00 43.73  ? 463 PHE B CA  1 
ATOM   9749  C  C   . PHE B 1 463 ? 228.352 217.728 199.598 1.00 44.20  ? 463 PHE B C   1 
ATOM   9750  O  O   . PHE B 1 463 ? 228.833 218.840 199.818 1.00 52.63  ? 463 PHE B O   1 
ATOM   9751  C  CB  . PHE B 1 463 ? 225.996 217.320 200.191 1.00 42.98  ? 463 PHE B CB  1 
ATOM   9752  C  CG  . PHE B 1 463 ? 224.990 216.777 201.130 1.00 46.05  ? 463 PHE B CG  1 
ATOM   9753  C  CD1 . PHE B 1 463 ? 224.432 217.578 202.096 1.00 49.73  ? 463 PHE B CD1 1 
ATOM   9754  C  CD2 . PHE B 1 463 ? 224.574 215.470 201.036 1.00 51.72  ? 463 PHE B CD2 1 
ATOM   9755  C  CE1 . PHE B 1 463 ? 223.488 217.081 202.955 1.00 53.41  ? 463 PHE B CE1 1 
ATOM   9756  C  CE2 . PHE B 1 463 ? 223.637 214.970 201.893 1.00 54.92  ? 463 PHE B CE2 1 
ATOM   9757  C  CZ  . PHE B 1 463 ? 223.092 215.773 202.853 1.00 57.07  ? 463 PHE B CZ  1 
ATOM   9758  N  N   . VAL B 1 464 ? 228.569 217.060 198.472 1.00 38.96  ? 464 VAL B N   1 
ATOM   9759  C  CA  . VAL B 1 464 ? 229.324 217.627 197.365 1.00 38.71  ? 464 VAL B CA  1 
ATOM   9760  C  C   . VAL B 1 464 ? 228.506 217.493 196.092 1.00 45.29  ? 464 VAL B C   1 
ATOM   9761  O  O   . VAL B 1 464 ? 228.047 216.397 195.749 1.00 54.49  ? 464 VAL B O   1 
ATOM   9762  C  CB  . VAL B 1 464 ? 230.697 216.960 197.199 1.00 40.40  ? 464 VAL B CB  1 
ATOM   9763  C  CG1 . VAL B 1 464 ? 231.196 217.141 195.800 1.00 39.81  ? 464 VAL B CG1 1 
ATOM   9764  C  CG2 . VAL B 1 464 ? 231.679 217.547 198.171 1.00 44.06  ? 464 VAL B CG2 1 
ATOM   9765  N  N   . LEU B 1 465 ? 228.325 218.611 195.400 1.00 44.38  ? 465 LEU B N   1 
ATOM   9766  C  CA  . LEU B 1 465 ? 227.639 218.675 194.119 1.00 43.33  ? 465 LEU B CA  1 
ATOM   9767  C  C   . LEU B 1 465 ? 228.660 219.051 193.056 1.00 46.31  ? 465 LEU B C   1 
ATOM   9768  O  O   . LEU B 1 465 ? 229.312 220.095 193.157 1.00 52.90  ? 465 LEU B O   1 
ATOM   9769  C  CB  . LEU B 1 465 ? 226.504 219.696 194.166 1.00 43.69  ? 465 LEU B CB  1 
ATOM   9770  C  CG  . LEU B 1 465 ? 225.624 219.849 192.934 1.00 43.31  ? 465 LEU B CG  1 
ATOM   9771  C  CD1 . LEU B 1 465 ? 224.889 218.570 192.644 1.00 49.19  ? 465 LEU B CD1 1 
ATOM   9772  C  CD2 . LEU B 1 465 ? 224.648 220.982 193.126 1.00 48.69  ? 465 LEU B CD2 1 
ATOM   9773  N  N   . VAL B 1 466 ? 228.792 218.214 192.038 1.00 43.56  ? 466 VAL B N   1 
ATOM   9774  C  CA  . VAL B 1 466 ? 229.790 218.385 190.993 1.00 43.32  ? 466 VAL B CA  1 
ATOM   9775  C  C   . VAL B 1 466 ? 229.071 218.694 189.692 1.00 49.29  ? 466 VAL B C   1 
ATOM   9776  O  O   . VAL B 1 466 ? 228.193 217.931 189.268 1.00 55.34  ? 466 VAL B O   1 
ATOM   9777  C  CB  . VAL B 1 466 ? 230.664 217.129 190.853 1.00 43.74  ? 466 VAL B CB  1 
ATOM   9778  C  CG1 . VAL B 1 466 ? 231.869 217.418 190.021 1.00 45.05  ? 466 VAL B CG1 1 
ATOM   9779  C  CG2 . VAL B 1 466 ? 231.086 216.644 192.214 1.00 45.67  ? 466 VAL B CG2 1 
ATOM   9780  N  N   . SER B 1 467 ? 229.430 219.816 189.066 1.00 50.12  ? 467 SER B N   1 
ATOM   9781  C  CA  . SER B 1 467 ? 228.833 220.203 187.793 1.00 54.22  ? 467 SER B CA  1 
ATOM   9782  C  C   . SER B 1 467 ? 229.888 220.788 186.867 1.00 59.26  ? 467 SER B C   1 
ATOM   9783  O  O   . SER B 1 467 ? 230.752 221.548 187.305 1.00 62.49  ? 467 SER B O   1 
ATOM   9784  C  CB  . SER B 1 467 ? 227.710 221.214 187.986 1.00 56.46  ? 467 SER B CB  1 
ATOM   9785  O  OG  . SER B 1 467 ? 227.216 221.642 186.732 1.00 59.92  ? 467 SER B OG  1 
ATOM   9786  N  N   . LEU B 1 468 ? 229.801 220.447 185.583 1.00 62.12  ? 468 LEU B N   1 
ATOM   9787  C  CA  . LEU B 1 468 ? 230.840 220.784 184.618 1.00 63.87  ? 468 LEU B CA  1 
ATOM   9788  C  C   . LEU B 1 468 ? 230.666 222.149 183.964 1.00 69.08  ? 468 LEU B C   1 
ATOM   9789  O  O   . LEU B 1 468 ? 231.534 222.550 183.182 1.00 68.67  ? 468 LEU B O   1 
ATOM   9790  C  CB  . LEU B 1 468 ? 230.912 219.719 183.524 1.00 65.37  ? 468 LEU B CB  1 
ATOM   9791  C  CG  . LEU B 1 468 ? 230.552 218.295 183.934 1.00 72.07  ? 468 LEU B CG  1 
ATOM   9792  C  CD1 . LEU B 1 468 ? 230.346 217.426 182.707 1.00 72.77  ? 468 LEU B CD1 1 
ATOM   9793  C  CD2 . LEU B 1 468 ? 231.635 217.713 184.829 1.00 73.63  ? 468 LEU B CD2 1 
ATOM   9794  N  N   . GLU B 1 469 ? 229.583 222.868 184.246 1.00 70.80  ? 469 GLU B N   1 
ATOM   9795  C  CA  . GLU B 1 469 ? 229.379 224.197 183.684 1.00 66.27  ? 469 GLU B CA  1 
ATOM   9796  C  C   . GLU B 1 469 ? 230.158 225.227 184.483 1.00 66.69  ? 469 GLU B C   1 
ATOM   9797  O  O   . GLU B 1 469 ? 229.906 225.418 185.675 1.00 69.21  ? 469 GLU B O   1 
ATOM   9798  C  CB  . GLU B 1 469 ? 227.896 224.552 183.661 1.00 65.49  ? 469 GLU B CB  1 
ATOM   9799  C  CG  . GLU B 1 469 ? 227.001 223.336 183.602 1.00 76.23  ? 469 GLU B CG  1 
ATOM   9800  C  CD  . GLU B 1 469 ? 225.567 223.644 183.961 1.00 82.59  ? 469 GLU B CD  1 
ATOM   9801  O  OE1 . GLU B 1 469 ? 225.162 223.352 185.105 1.00 82.93  ? 469 GLU B OE1 1 
ATOM   9802  O  OE2 . GLU B 1 469 ? 224.840 224.171 183.093 1.00 85.06  ? 469 GLU B OE2 1 
ATOM   9803  N  N   . ASN B 1 470 ? 231.087 225.907 183.814 1.00 68.59  ? 470 ASN B N   1 
ATOM   9804  C  CA  . ASN B 1 470 ? 231.993 226.849 184.458 1.00 70.33  ? 470 ASN B CA  1 
ATOM   9805  C  C   . ASN B 1 470 ? 231.572 228.299 184.250 1.00 71.70  ? 470 ASN B C   1 
ATOM   9806  O  O   . ASN B 1 470 ? 232.335 229.215 184.566 1.00 67.78  ? 470 ASN B O   1 
ATOM   9807  C  CB  . ASN B 1 470 ? 233.412 226.632 183.948 1.00 69.98  ? 470 ASN B CB  1 
ATOM   9808  C  CG  . ASN B 1 470 ? 233.471 226.523 182.454 1.00 76.53  ? 470 ASN B CG  1 
ATOM   9809  O  OD1 . ASN B 1 470 ? 232.450 226.339 181.798 1.00 74.82  ? 470 ASN B OD1 1 
ATOM   9810  N  ND2 . ASN B 1 470 ? 234.669 226.639 181.899 1.00 81.96  ? 470 ASN B ND2 1 
ATOM   9811  N  N   . ASP B 1 471 ? 230.374 228.522 183.724 1.00 73.19  ? 471 ASP B N   1 
ATOM   9812  C  CA  . ASP B 1 471 ? 229.846 229.870 183.606 1.00 70.17  ? 471 ASP B CA  1 
ATOM   9813  C  C   . ASP B 1 471 ? 229.584 230.450 184.983 1.00 66.13  ? 471 ASP B C   1 
ATOM   9814  O  O   . ASP B 1 471 ? 229.081 229.766 185.875 1.00 70.37  ? 471 ASP B O   1 
ATOM   9815  C  CB  . ASP B 1 471 ? 228.550 229.858 182.803 1.00 71.43  ? 471 ASP B CB  1 
ATOM   9816  C  CG  . ASP B 1 471 ? 227.750 231.132 182.968 1.00 74.55  ? 471 ASP B CG  1 
ATOM   9817  O  OD1 . ASP B 1 471 ? 228.355 232.218 183.087 1.00 76.33  ? 471 ASP B OD1 1 
ATOM   9818  O  OD2 . ASP B 1 471 ? 226.508 231.047 182.997 1.00 74.66  ? 471 ASP B OD2 1 
ATOM   9819  N  N   . VAL B 1 472 ? 229.910 231.727 185.152 1.00 59.90  ? 472 VAL B N   1 
ATOM   9820  C  CA  . VAL B 1 472 ? 229.628 232.380 186.421 1.00 63.88  ? 472 VAL B CA  1 
ATOM   9821  C  C   . VAL B 1 472 ? 228.129 232.573 186.611 1.00 66.37  ? 472 VAL B C   1 
ATOM   9822  O  O   . VAL B 1 472 ? 227.610 232.426 187.724 1.00 69.81  ? 472 VAL B O   1 
ATOM   9823  C  CB  . VAL B 1 472 ? 230.388 233.706 186.512 1.00 66.06  ? 472 VAL B CB  1 
ATOM   9824  C  CG1 . VAL B 1 472 ? 230.001 234.430 187.784 1.00 68.65  ? 472 VAL B CG1 1 
ATOM   9825  C  CG2 . VAL B 1 472 ? 231.871 233.433 186.462 1.00 68.88  ? 472 VAL B CG2 1 
ATOM   9826  N  N   . SER B 1 473 ? 227.407 232.897 185.538 1.00 65.60  ? 473 SER B N   1 
ATOM   9827  C  CA  . SER B 1 473 ? 225.967 233.100 185.666 1.00 69.09  ? 473 SER B CA  1 
ATOM   9828  C  C   . SER B 1 473 ? 225.259 231.822 186.101 1.00 68.40  ? 473 SER B C   1 
ATOM   9829  O  O   . SER B 1 473 ? 224.425 231.843 187.018 1.00 69.75  ? 473 SER B O   1 
ATOM   9830  C  CB  . SER B 1 473 ? 225.392 233.608 184.346 1.00 72.23  ? 473 SER B CB  1 
ATOM   9831  O  OG  . SER B 1 473 ? 225.505 235.016 184.244 1.00 70.42  ? 473 SER B OG  1 
ATOM   9832  N  N   . ASN B 1 474 ? 225.581 230.696 185.462 1.00 64.90  ? 474 ASN B N   1 
ATOM   9833  C  CA  . ASN B 1 474 ? 224.960 229.435 185.846 1.00 67.25  ? 474 ASN B CA  1 
ATOM   9834  C  C   . ASN B 1 474 ? 225.341 229.038 187.264 1.00 68.65  ? 474 ASN B C   1 
ATOM   9835  O  O   . ASN B 1 474 ? 224.507 228.517 188.009 1.00 70.61  ? 474 ASN B O   1 
ATOM   9836  C  CB  . ASN B 1 474 ? 225.343 228.329 184.866 1.00 72.37  ? 474 ASN B CB  1 
ATOM   9837  C  CG  . ASN B 1 474 ? 224.789 228.558 183.479 1.00 78.42  ? 474 ASN B CG  1 
ATOM   9838  O  OD1 . ASN B 1 474 ? 225.534 228.614 182.503 1.00 81.91  ? 474 ASN B OD1 1 
ATOM   9839  N  ND2 . ASN B 1 474 ? 223.471 228.690 183.383 1.00 78.41  ? 474 ASN B ND2 1 
ATOM   9840  N  N   . ILE B 1 475 ? 226.601 229.253 187.647 1.00 64.25  ? 475 ILE B N   1 
ATOM   9841  C  CA  . ILE B 1 475 ? 227.029 228.919 189.001 1.00 56.84  ? 475 ILE B CA  1 
ATOM   9842  C  C   . ILE B 1 475 ? 226.246 229.730 190.019 1.00 59.91  ? 475 ILE B C   1 
ATOM   9843  O  O   . ILE B 1 475 ? 225.774 229.196 191.034 1.00 63.66  ? 475 ILE B O   1 
ATOM   9844  C  CB  . ILE B 1 475 ? 228.542 229.132 189.149 1.00 53.11  ? 475 ILE B CB  1 
ATOM   9845  C  CG1 . ILE B 1 475 ? 229.309 228.039 188.420 1.00 55.97  ? 475 ILE B CG1 1 
ATOM   9846  C  CG2 . ILE B 1 475 ? 228.925 229.120 190.595 1.00 53.84  ? 475 ILE B CG2 1 
ATOM   9847  C  CD1 . ILE B 1 475 ? 230.779 228.341 188.266 1.00 59.01  ? 475 ILE B CD1 1 
ATOM   9848  N  N   . THR B 1 476 ? 226.077 231.024 189.762 1.00 61.52  ? 476 THR B N   1 
ATOM   9849  C  CA  . THR B 1 476 ? 225.296 231.850 190.673 1.00 64.02  ? 476 THR B CA  1 
ATOM   9850  C  C   . THR B 1 476 ? 223.858 231.364 190.754 1.00 67.82  ? 476 THR B C   1 
ATOM   9851  O  O   . THR B 1 476 ? 223.270 231.319 191.841 1.00 72.26  ? 476 THR B O   1 
ATOM   9852  C  CB  . THR B 1 476 ? 225.340 233.310 190.233 1.00 66.10  ? 476 THR B CB  1 
ATOM   9853  O  OG1 . THR B 1 476 ? 225.178 233.385 188.812 1.00 72.39  ? 476 THR B OG1 1 
ATOM   9854  C  CG2 . THR B 1 476 ? 226.666 233.938 190.615 1.00 63.66  ? 476 THR B CG2 1 
ATOM   9855  N  N   . GLN B 1 477 ? 223.273 230.999 189.613 1.00 68.43  ? 477 GLN B N   1 
ATOM   9856  C  CA  . GLN B 1 477 ? 221.888 230.540 189.621 1.00 70.33  ? 477 GLN B CA  1 
ATOM   9857  C  C   . GLN B 1 477 ? 221.738 229.245 190.408 1.00 68.75  ? 477 GLN B C   1 
ATOM   9858  O  O   . GLN B 1 477 ? 220.776 229.078 191.166 1.00 71.79  ? 477 GLN B O   1 
ATOM   9859  C  CB  . GLN B 1 477 ? 221.387 230.364 188.190 1.00 72.79  ? 477 GLN B CB  1 
ATOM   9860  C  CG  . GLN B 1 477 ? 219.878 230.414 188.055 1.00 79.70  ? 477 GLN B CG  1 
ATOM   9861  C  CD  . GLN B 1 477 ? 219.246 231.411 189.003 1.00 84.59  ? 477 GLN B CD  1 
ATOM   9862  O  OE1 . GLN B 1 477 ? 219.299 232.619 188.775 1.00 87.33  ? 477 GLN B OE1 1 
ATOM   9863  N  NE2 . GLN B 1 477 ? 218.638 230.910 190.072 1.00 83.18  ? 477 GLN B NE2 1 
ATOM   9864  N  N   . ILE B 1 478 ? 222.674 228.313 190.234 1.00 64.35  ? 478 ILE B N   1 
ATOM   9865  C  CA  . ILE B 1 478 ? 222.604 227.046 190.953 1.00 63.27  ? 478 ILE B CA  1 
ATOM   9866  C  C   . ILE B 1 478 ? 222.728 227.288 192.447 1.00 66.85  ? 478 ILE B C   1 
ATOM   9867  O  O   . ILE B 1 478 ? 221.991 226.704 193.254 1.00 72.95  ? 478 ILE B O   1 
ATOM   9868  C  CB  . ILE B 1 478 ? 223.696 226.083 190.458 1.00 63.57  ? 478 ILE B CB  1 
ATOM   9869  C  CG1 . ILE B 1 478 ? 223.525 225.767 188.979 1.00 66.72  ? 478 ILE B CG1 1 
ATOM   9870  C  CG2 . ILE B 1 478 ? 223.618 224.787 191.220 1.00 61.60  ? 478 ILE B CG2 1 
ATOM   9871  C  CD1 . ILE B 1 478 ? 224.664 224.955 188.415 1.00 63.63  ? 478 ILE B CD1 1 
ATOM   9872  N  N   . ALA B 1 479 ? 223.668 228.150 192.840 1.00 65.41  ? 479 ALA B N   1 
ATOM   9873  C  CA  . ALA B 1 479 ? 223.837 228.456 194.253 1.00 67.27  ? 479 ALA B CA  1 
ATOM   9874  C  C   . ALA B 1 479 ? 222.580 229.082 194.834 1.00 70.95  ? 479 ALA B C   1 
ATOM   9875  O  O   . ALA B 1 479 ? 222.172 228.745 195.949 1.00 74.00  ? 479 ALA B O   1 
ATOM   9876  C  CB  . ALA B 1 479 ? 225.035 229.380 194.451 1.00 60.38  ? 479 ALA B CB  1 
ATOM   9877  N  N   . ASP B 1 480 ? 221.957 230.001 194.099 1.00 73.45  ? 480 ASP B N   1 
ATOM   9878  C  CA  . ASP B 1 480 ? 220.738 230.629 194.599 1.00 76.94  ? 480 ASP B CA  1 
ATOM   9879  C  C   . ASP B 1 480 ? 219.611 229.615 194.731 1.00 79.24  ? 480 ASP B C   1 
ATOM   9880  O  O   . ASP B 1 480 ? 218.857 229.635 195.713 1.00 81.93  ? 480 ASP B O   1 
ATOM   9881  C  CB  . ASP B 1 480 ? 220.323 231.778 193.683 1.00 76.14  ? 480 ASP B CB  1 
ATOM   9882  C  CG  . ASP B 1 480 ? 220.996 233.083 194.050 1.00 79.67  ? 480 ASP B CG  1 
ATOM   9883  O  OD1 . ASP B 1 480 ? 221.078 233.391 195.256 1.00 81.04  ? 480 ASP B OD1 1 
ATOM   9884  O  OD2 . ASP B 1 480 ? 221.444 233.801 193.132 1.00 76.79  ? 480 ASP B OD2 1 
ATOM   9885  N  N   . GLU B 1 481 ? 219.477 228.720 193.750 1.00 78.53  ? 481 GLU B N   1 
ATOM   9886  C  CA  . GLU B 1 481 ? 218.441 227.698 193.819 1.00 78.58  ? 481 GLU B CA  1 
ATOM   9887  C  C   . GLU B 1 481 ? 218.635 226.814 195.039 1.00 77.53  ? 481 GLU B C   1 
ATOM   9888  O  O   . GLU B 1 481 ? 217.678 226.527 195.771 1.00 80.65  ? 481 GLU B O   1 
ATOM   9889  C  CB  . GLU B 1 481 ? 218.453 226.859 192.540 1.00 77.17  ? 481 GLU B CB  1 
ATOM   9890  C  CG  . GLU B 1 481 ? 217.623 225.550 192.510 1.00 85.00  ? 481 GLU B CG  1 
ATOM   9891  C  CD  . GLU B 1 481 ? 216.213 225.600 193.115 1.00 89.04  ? 481 GLU B CD  1 
ATOM   9892  O  OE1 . GLU B 1 481 ? 215.480 224.611 192.923 1.00 89.98  ? 481 GLU B OE1 1 
ATOM   9893  O  OE2 . GLU B 1 481 ? 215.794 226.604 193.725 1.00 86.92  ? 481 GLU B OE2 1 
ATOM   9894  N  N   . LEU B 1 482 ? 219.871 226.386 195.286 1.00 73.45  ? 482 LEU B N   1 
ATOM   9895  C  CA  . LEU B 1 482 ? 220.131 225.570 196.464 1.00 72.67  ? 482 LEU B CA  1 
ATOM   9896  C  C   . LEU B 1 482 ? 219.858 226.343 197.742 1.00 74.50  ? 482 LEU B C   1 
ATOM   9897  O  O   . LEU B 1 482 ? 219.287 225.801 198.692 1.00 77.86  ? 482 LEU B O   1 
ATOM   9898  C  CB  . LEU B 1 482 ? 221.567 225.064 196.454 1.00 69.94  ? 482 LEU B CB  1 
ATOM   9899  C  CG  . LEU B 1 482 ? 221.856 223.922 195.494 1.00 67.07  ? 482 LEU B CG  1 
ATOM   9900  C  CD1 . LEU B 1 482 ? 223.302 223.521 195.603 1.00 64.41  ? 482 LEU B CD1 1 
ATOM   9901  C  CD2 . LEU B 1 482 ? 220.948 222.758 195.794 1.00 67.08  ? 482 LEU B CD2 1 
ATOM   9902  N  N   . ARG B 1 483 ? 220.262 227.610 197.790 1.00 74.57  ? 483 ARG B N   1 
ATOM   9903  C  CA  . ARG B 1 483 ? 220.066 228.392 199.001 1.00 80.98  ? 483 ARG B CA  1 
ATOM   9904  C  C   . ARG B 1 483 ? 218.586 228.552 199.313 1.00 84.37  ? 483 ARG B C   1 
ATOM   9905  O  O   . ARG B 1 483 ? 218.182 228.490 200.480 1.00 86.16  ? 483 ARG B O   1 
ATOM   9906  C  CB  . ARG B 1 483 ? 220.738 229.756 198.858 1.00 84.11  ? 483 ARG B CB  1 
ATOM   9907  C  CG  . ARG B 1 483 ? 221.321 230.306 200.148 1.00 84.00  ? 483 ARG B CG  1 
ATOM   9908  C  CD  . ARG B 1 483 ? 220.301 231.144 200.901 1.00 86.66  ? 483 ARG B CD  1 
ATOM   9909  N  NE  . ARG B 1 483 ? 219.500 231.969 200.006 1.00 89.91  ? 483 ARG B NE  1 
ATOM   9910  C  CZ  . ARG B 1 483 ? 219.901 233.119 199.482 1.00 89.24  ? 483 ARG B CZ  1 
ATOM   9911  N  NH1 . ARG B 1 483 ? 221.097 233.619 199.745 1.00 86.34  ? 483 ARG B NH1 1 
ATOM   9912  N  NH2 . ARG B 1 483 ? 219.081 233.785 198.674 1.00 85.73  ? 483 ARG B NH2 1 
ATOM   9913  N  N   . ASN B 1 484 ? 217.760 228.751 198.289 1.00 83.24  ? 484 ASN B N   1 
ATOM   9914  C  CA  . ASN B 1 484 ? 216.346 228.994 198.531 1.00 84.88  ? 484 ASN B CA  1 
ATOM   9915  C  C   . ASN B 1 484 ? 215.506 227.725 198.556 1.00 84.88  ? 484 ASN B C   1 
ATOM   9916  O  O   . ASN B 1 484 ? 214.311 227.807 198.859 1.00 86.77  ? 484 ASN B O   1 
ATOM   9917  C  CB  . ASN B 1 484 ? 215.784 229.963 197.486 1.00 83.85  ? 484 ASN B CB  1 
ATOM   9918  C  CG  . ASN B 1 484 ? 215.957 229.463 196.071 1.00 83.63  ? 484 ASN B CG  1 
ATOM   9919  O  OD1 . ASN B 1 484 ? 215.487 228.385 195.718 1.00 83.05  ? 484 ASN B OD1 1 
ATOM   9920  N  ND2 . ASN B 1 484 ? 216.635 230.251 195.248 1.00 84.11  ? 484 ASN B ND2 1 
ATOM   9921  N  N   . VAL B 1 485 ? 216.079 226.561 198.242 1.00 83.57  ? 485 VAL B N   1 
ATOM   9922  C  CA  . VAL B 1 485 ? 215.272 225.347 198.314 1.00 85.03  ? 485 VAL B CA  1 
ATOM   9923  C  C   . VAL B 1 485 ? 214.924 225.012 199.758 1.00 86.48  ? 485 VAL B C   1 
ATOM   9924  O  O   . VAL B 1 485 ? 213.954 224.290 200.018 1.00 87.79  ? 485 VAL B O   1 
ATOM   9925  C  CB  . VAL B 1 485 ? 215.981 224.166 197.625 1.00 84.46  ? 485 VAL B CB  1 
ATOM   9926  C  CG1 . VAL B 1 485 ? 217.127 223.660 198.471 1.00 81.38  ? 485 VAL B CG1 1 
ATOM   9927  C  CG2 . VAL B 1 485 ? 214.994 223.049 197.325 1.00 81.13  ? 485 VAL B CG2 1 
ATOM   9928  N  N   . VAL B 1 486 ? 215.685 225.528 200.719 1.00 86.48  ? 486 VAL B N   1 
ATOM   9929  C  CA  . VAL B 1 486 ? 215.437 225.216 202.121 1.00 89.59  ? 486 VAL B CA  1 
ATOM   9930  C  C   . VAL B 1 486 ? 214.655 226.347 202.770 1.00 90.91  ? 486 VAL B C   1 
ATOM   9931  O  O   . VAL B 1 486 ? 214.597 226.448 204.000 1.00 89.54  ? 486 VAL B O   1 
ATOM   9932  C  CB  . VAL B 1 486 ? 216.752 224.954 202.878 1.00 88.73  ? 486 VAL B CB  1 
ATOM   9933  C  CG1 . VAL B 1 486 ? 217.449 223.723 202.324 1.00 86.80  ? 486 VAL B CG1 1 
ATOM   9934  C  CG2 . VAL B 1 486 ? 217.662 226.170 202.798 1.00 84.33  ? 486 VAL B CG2 1 
ATOM   9935  N  N   . SER B 1 487 ? 214.038 227.199 201.950 1.00 92.95  ? 487 SER B N   1 
ATOM   9936  C  CA  . SER B 1 487 ? 213.320 228.350 202.488 1.00 95.80  ? 487 SER B CA  1 
ATOM   9937  C  C   . SER B 1 487 ? 212.158 227.916 203.372 1.00 98.12  ? 487 SER B C   1 
ATOM   9938  O  O   . SER B 1 487 ? 211.961 228.463 204.462 1.00 101.85 ? 487 SER B O   1 
ATOM   9939  C  CB  . SER B 1 487 ? 212.825 229.239 201.350 1.00 94.17  ? 487 SER B CB  1 
ATOM   9940  O  OG  . SER B 1 487 ? 212.376 228.460 200.256 1.00 91.40  ? 487 SER B OG  1 
ATOM   9941  N  N   . LYS B 1 488 ? 211.381 226.938 202.922 1.00 94.27  ? 488 LYS B N   1 
ATOM   9942  C  CA  . LYS B 1 488 ? 210.290 226.434 203.734 1.00 93.95  ? 488 LYS B CA  1 
ATOM   9943  C  C   . LYS B 1 488 ? 210.840 225.684 204.945 1.00 100.24 ? 488 LYS B C   1 
ATOM   9944  O  O   . LYS B 1 488 ? 211.895 225.049 204.865 1.00 100.20 ? 488 LYS B O   1 
ATOM   9945  C  CB  . LYS B 1 488 ? 209.394 225.511 202.915 1.00 94.62  ? 488 LYS B CB  1 
ATOM   9946  C  CG  . LYS B 1 488 ? 208.594 226.224 201.841 1.00 102.55 ? 488 LYS B CG  1 
ATOM   9947  C  CD  . LYS B 1 488 ? 208.633 225.460 200.527 1.00 102.11 ? 488 LYS B CD  1 
ATOM   9948  C  CE  . LYS B 1 488 ? 210.050 225.368 199.983 1.00 100.81 ? 488 LYS B CE  1 
ATOM   9949  N  NZ  . LYS B 1 488 ? 210.689 226.708 199.870 1.00 98.41  ? 488 LYS B NZ  1 
ATOM   9950  N  N   . PRO B 1 489 ? 210.154 225.754 206.082 1.00 104.45 ? 489 PRO B N   1 
ATOM   9951  C  CA  . PRO B 1 489 ? 210.628 225.032 207.266 1.00 102.97 ? 489 PRO B CA  1 
ATOM   9952  C  C   . PRO B 1 489 ? 210.592 223.530 207.041 1.00 100.92 ? 489 PRO B C   1 
ATOM   9953  O  O   . PRO B 1 489 ? 209.756 223.009 206.302 1.00 98.96  ? 489 PRO B O   1 
ATOM   9954  C  CB  . PRO B 1 489 ? 209.645 225.458 208.364 1.00 105.52 ? 489 PRO B CB  1 
ATOM   9955  C  CG  . PRO B 1 489 ? 208.994 226.707 207.847 1.00 107.54 ? 489 PRO B CG  1 
ATOM   9956  C  CD  . PRO B 1 489 ? 208.949 226.550 206.361 1.00 106.57 ? 489 PRO B CD  1 
ATOM   9957  N  N   . ILE B 1 490 ? 211.523 222.832 207.688 1.00 103.82 ? 490 ILE B N   1 
ATOM   9958  C  CA  . ILE B 1 490 ? 211.612 221.377 207.584 1.00 107.66 ? 490 ILE B CA  1 
ATOM   9959  C  C   . ILE B 1 490 ? 210.594 220.787 208.556 1.00 113.01 ? 490 ILE B C   1 
ATOM   9960  O  O   . ILE B 1 490 ? 210.859 220.654 209.752 1.00 114.20 ? 490 ILE B O   1 
ATOM   9961  C  CB  . ILE B 1 490 ? 213.027 220.870 207.861 1.00 102.61 ? 490 ILE B CB  1 
ATOM   9962  C  CG1 . ILE B 1 490 ? 213.987 221.403 206.799 1.00 100.10 ? 490 ILE B CG1 1 
ATOM   9963  C  CG2 . ILE B 1 490 ? 213.053 219.355 207.881 1.00 96.96  ? 490 ILE B CG2 1 
ATOM   9964  C  CD1 . ILE B 1 490 ? 215.375 220.817 206.880 1.00 92.73  ? 490 ILE B CD1 1 
ATOM   9965  N  N   . MET B 1 491 ? 209.422 220.429 208.039 1.00 113.56 ? 491 MET B N   1 
ATOM   9966  C  CA  . MET B 1 491 ? 208.328 219.916 208.857 1.00 111.94 ? 491 MET B CA  1 
ATOM   9967  C  C   . MET B 1 491 ? 208.616 218.472 209.237 1.00 111.12 ? 491 MET B C   1 
ATOM   9968  O  O   . MET B 1 491 ? 208.549 217.575 208.390 1.00 113.65 ? 491 MET B O   1 
ATOM   9969  C  CB  . MET B 1 491 ? 207.009 220.022 208.097 1.00 113.44 ? 491 MET B CB  1 
ATOM   9970  C  CG  . MET B 1 491 ? 205.717 219.709 208.873 1.00 113.97 ? 491 MET B CG  1 
ATOM   9971  S  SD  . MET B 1 491 ? 205.575 219.822 210.677 1.00 125.00 ? 491 MET B SD  1 
ATOM   9972  C  CE  . MET B 1 491 ? 206.365 221.377 211.087 1.00 115.07 ? 491 MET B CE  1 
ATOM   9973  N  N   . ILE B 1 492 ? 208.931 218.238 210.507 1.00 111.14 ? 492 ILE B N   1 
ATOM   9974  C  CA  . ILE B 1 492 ? 209.121 216.889 211.038 1.00 112.43 ? 492 ILE B CA  1 
ATOM   9975  C  C   . ILE B 1 492 ? 208.220 216.738 212.265 1.00 116.77 ? 492 ILE B C   1 
ATOM   9976  O  O   . ILE B 1 492 ? 208.532 217.209 213.364 1.00 118.43 ? 492 ILE B O   1 
ATOM   9977  C  CB  . ILE B 1 492 ? 210.594 216.565 211.338 1.00 111.82 ? 492 ILE B CB  1 
ATOM   9978  C  CG1 . ILE B 1 492 ? 211.177 217.359 212.512 1.00 113.16 ? 492 ILE B CG1 1 
ATOM   9979  C  CG2 . ILE B 1 492 ? 211.450 216.773 210.094 1.00 105.50 ? 492 ILE B CG2 1 
ATOM   9980  C  CD1 . ILE B 1 492 ? 212.532 216.862 212.972 1.00 104.02 ? 492 ILE B CD1 1 
ATOM   9981  N  N   . ASP B 1 493 ? 207.059 216.112 212.064 1.00 115.63 ? 493 ASP B N   1 
ATOM   9982  C  CA  . ASP B 1 493 ? 206.119 215.763 213.129 1.00 116.38 ? 493 ASP B CA  1 
ATOM   9983  C  C   . ASP B 1 493 ? 205.796 217.000 213.980 1.00 119.50 ? 493 ASP B C   1 
ATOM   9984  O  O   . ASP B 1 493 ? 206.219 217.157 215.127 1.00 118.01 ? 493 ASP B O   1 
ATOM   9985  C  CB  . ASP B 1 493 ? 206.664 214.570 213.935 1.00 116.79 ? 493 ASP B CB  1 
ATOM   9986  C  CG  . ASP B 1 493 ? 206.108 214.478 215.346 1.00 123.56 ? 493 ASP B CG  1 
ATOM   9987  O  OD1 . ASP B 1 493 ? 206.815 214.871 216.300 1.00 122.60 ? 493 ASP B OD1 1 
ATOM   9988  O  OD2 . ASP B 1 493 ? 204.961 214.011 215.501 1.00 127.18 ? 493 ASP B OD2 1 
ATOM   9989  N  N   . ASP B 1 494 ? 205.098 217.929 213.326 1.00 120.01 ? 494 ASP B N   1 
ATOM   9990  C  CA  . ASP B 1 494 ? 204.553 219.118 213.984 1.00 121.81 ? 494 ASP B CA  1 
ATOM   9991  C  C   . ASP B 1 494 ? 205.628 219.867 214.767 1.00 120.19 ? 494 ASP B C   1 
ATOM   9992  O  O   . ASP B 1 494 ? 205.399 220.343 215.881 1.00 118.93 ? 494 ASP B O   1 
ATOM   9993  C  CB  . ASP B 1 494 ? 203.379 218.748 214.891 1.00 125.16 ? 494 ASP B CB  1 
ATOM   9994  C  CG  . ASP B 1 494 ? 202.397 219.890 215.067 1.00 129.91 ? 494 ASP B CG  1 
ATOM   9995  O  OD1 . ASP B 1 494 ? 202.334 220.765 214.178 1.00 132.10 ? 494 ASP B OD1 1 
ATOM   9996  O  OD2 . ASP B 1 494 ? 201.689 219.911 216.095 1.00 131.88 ? 494 ASP B OD2 1 
ATOM   9997  N  N   . LYS B 1 495 ? 206.817 219.968 214.181 1.00 120.60 ? 495 LYS B N   1 
ATOM   9998  C  CA  . LYS B 1 495 ? 207.949 220.635 214.825 1.00 120.36 ? 495 LYS B CA  1 
ATOM   9999  C  C   . LYS B 1 495 ? 208.871 221.176 213.748 1.00 118.35 ? 495 LYS B C   1 
ATOM   10000 O  O   . LYS B 1 495 ? 209.775 220.483 213.266 1.00 114.85 ? 495 LYS B O   1 
ATOM   10001 C  CB  . LYS B 1 495 ? 208.693 219.681 215.760 1.00 121.37 ? 495 LYS B CB  1 
ATOM   10002 C  CG  . LYS B 1 495 ? 209.119 220.312 217.077 1.00 120.91 ? 495 LYS B CG  1 
ATOM   10003 C  CD  . LYS B 1 495 ? 207.922 220.838 217.853 1.00 120.56 ? 495 LYS B CD  1 
ATOM   10004 C  CE  . LYS B 1 495 ? 208.359 221.662 219.052 1.00 119.13 ? 495 LYS B CE  1 
ATOM   10005 N  NZ  . LYS B 1 495 ? 209.123 222.874 218.646 1.00 120.54 ? 495 LYS B NZ  1 
ATOM   10006 N  N   . PRO B 1 496 ? 208.668 222.421 213.339 1.00 122.27 ? 496 PRO B N   1 
ATOM   10007 C  CA  . PRO B 1 496 ? 209.461 223.018 212.245 1.00 118.04 ? 496 PRO B CA  1 
ATOM   10008 C  C   . PRO B 1 496 ? 210.825 223.551 212.676 1.00 111.99 ? 496 PRO B C   1 
ATOM   10009 O  O   . PRO B 1 496 ? 211.018 224.730 212.963 1.00 114.30 ? 496 PRO B O   1 
ATOM   10010 C  CB  . PRO B 1 496 ? 208.548 224.143 211.752 1.00 118.16 ? 496 PRO B CB  1 
ATOM   10011 C  CG  . PRO B 1 496 ? 207.804 224.567 212.975 1.00 121.81 ? 496 PRO B CG  1 
ATOM   10012 C  CD  . PRO B 1 496 ? 207.611 223.329 213.817 1.00 125.33 ? 496 PRO B CD  1 
ATOM   10013 N  N   . PHE B 1 497 ? 211.811 222.663 212.736 1.00 106.38 ? 497 PHE B N   1 
ATOM   10014 C  CA  . PHE B 1 497 ? 213.185 223.110 212.928 1.00 103.56 ? 497 PHE B CA  1 
ATOM   10015 C  C   . PHE B 1 497 ? 213.664 223.797 211.657 1.00 100.32 ? 497 PHE B C   1 
ATOM   10016 O  O   . PHE B 1 497 ? 213.672 223.168 210.595 1.00 96.75  ? 497 PHE B O   1 
ATOM   10017 C  CB  . PHE B 1 497 ? 214.132 221.958 213.252 1.00 102.15 ? 497 PHE B CB  1 
ATOM   10018 C  CG  . PHE B 1 497 ? 213.758 221.151 214.464 1.00 104.63 ? 497 PHE B CG  1 
ATOM   10019 C  CD1 . PHE B 1 497 ? 212.543 220.496 214.556 1.00 105.74 ? 497 PHE B CD1 1 
ATOM   10020 C  CD2 . PHE B 1 497 ? 214.641 221.056 215.524 1.00 102.75 ? 497 PHE B CD2 1 
ATOM   10021 C  CE1 . PHE B 1 497 ? 212.223 219.757 215.675 1.00 106.43 ? 497 PHE B CE1 1 
ATOM   10022 C  CE2 . PHE B 1 497 ? 214.327 220.322 216.643 1.00 103.03 ? 497 PHE B CE2 1 
ATOM   10023 C  CZ  . PHE B 1 497 ? 213.115 219.673 216.722 1.00 104.45 ? 497 PHE B CZ  1 
ATOM   10024 N  N   . PRO B 1 498 ? 214.058 225.065 211.710 1.00 98.35  ? 498 PRO B N   1 
ATOM   10025 C  CA  . PRO B 1 498 ? 214.632 225.702 210.522 1.00 92.00  ? 498 PRO B CA  1 
ATOM   10026 C  C   . PRO B 1 498 ? 216.075 225.272 210.337 1.00 88.15  ? 498 PRO B C   1 
ATOM   10027 O  O   . PRO B 1 498 ? 216.822 225.103 211.304 1.00 88.48  ? 498 PRO B O   1 
ATOM   10028 C  CB  . PRO B 1 498 ? 214.533 227.198 210.839 1.00 94.82  ? 498 PRO B CB  1 
ATOM   10029 C  CG  . PRO B 1 498 ? 214.565 227.255 212.327 1.00 97.24  ? 498 PRO B CG  1 
ATOM   10030 C  CD  . PRO B 1 498 ? 213.844 226.027 212.804 1.00 100.70 ? 498 PRO B CD  1 
ATOM   10031 N  N   . LEU B 1 499 ? 216.463 225.083 209.083 1.00 83.53  ? 499 LEU B N   1 
ATOM   10032 C  CA  . LEU B 1 499 ? 217.814 224.673 208.741 1.00 82.30  ? 499 LEU B CA  1 
ATOM   10033 C  C   . LEU B 1 499 ? 218.335 225.564 207.626 1.00 76.33  ? 499 LEU B C   1 
ATOM   10034 O  O   . LEU B 1 499 ? 217.559 226.095 206.830 1.00 74.53  ? 499 LEU B O   1 
ATOM   10035 C  CB  . LEU B 1 499 ? 217.868 223.197 208.318 1.00 84.44  ? 499 LEU B CB  1 
ATOM   10036 C  CG  . LEU B 1 499 ? 217.946 222.148 209.432 1.00 87.08  ? 499 LEU B CG  1 
ATOM   10037 C  CD1 . LEU B 1 499 ? 216.609 221.953 210.124 1.00 88.83  ? 499 LEU B CD1 1 
ATOM   10038 C  CD2 . LEU B 1 499 ? 218.444 220.823 208.888 1.00 86.86  ? 499 LEU B CD2 1 
ATOM   10039 N  N   . THR B 1 500 ? 219.653 225.741 207.579 1.00 74.93  ? 500 THR B N   1 
ATOM   10040 C  CA  . THR B 1 500 ? 220.258 226.627 206.594 1.00 72.28  ? 500 THR B CA  1 
ATOM   10041 C  C   . THR B 1 500 ? 221.352 225.896 205.833 1.00 69.21  ? 500 THR B C   1 
ATOM   10042 O  O   . THR B 1 500 ? 221.716 224.766 206.161 1.00 71.10  ? 500 THR B O   1 
ATOM   10043 C  CB  . THR B 1 500 ? 220.828 227.891 207.247 1.00 77.16  ? 500 THR B CB  1 
ATOM   10044 O  OG1 . THR B 1 500 ? 221.505 227.538 208.459 1.00 81.16  ? 500 THR B OG1 1 
ATOM   10045 C  CG2 . THR B 1 500 ? 219.715 228.881 207.556 1.00 78.93  ? 500 THR B CG2 1 
ATOM   10046 N  N   . LEU B 1 501 ? 221.888 226.557 204.812 1.00 68.46  ? 501 LEU B N   1 
ATOM   10047 C  CA  . LEU B 1 501 ? 222.903 225.968 203.952 1.00 65.65  ? 501 LEU B CA  1 
ATOM   10048 C  C   . LEU B 1 501 ? 224.105 226.892 203.834 1.00 60.99  ? 501 LEU B C   1 
ATOM   10049 O  O   . LEU B 1 501 ? 223.958 228.114 203.708 1.00 65.66  ? 501 LEU B O   1 
ATOM   10050 C  CB  . LEU B 1 501 ? 222.347 225.670 202.562 1.00 62.79  ? 501 LEU B CB  1 
ATOM   10051 C  CG  . LEU B 1 501 ? 221.179 224.693 202.477 1.00 67.30  ? 501 LEU B CG  1 
ATOM   10052 C  CD1 . LEU B 1 501 ? 220.847 224.414 201.031 1.00 74.90  ? 501 LEU B CD1 1 
ATOM   10053 C  CD2 . LEU B 1 501 ? 221.504 223.406 203.201 1.00 66.66  ? 501 LEU B CD2 1 
ATOM   10054 N  N   . SER B 1 502 ? 225.295 226.301 203.881 1.00 54.09  ? 502 SER B N   1 
ATOM   10055 C  CA  . SER B 1 502 ? 226.550 227.019 203.711 1.00 48.80  ? 502 SER B CA  1 
ATOM   10056 C  C   . SER B 1 502 ? 227.301 226.361 202.566 1.00 48.77  ? 502 SER B C   1 
ATOM   10057 O  O   . SER B 1 502 ? 227.713 225.205 202.679 1.00 53.70  ? 502 SER B O   1 
ATOM   10058 C  CB  . SER B 1 502 ? 227.373 226.989 204.992 1.00 56.02  ? 502 SER B CB  1 
ATOM   10059 O  OG  . SER B 1 502 ? 227.453 225.672 205.500 1.00 64.26  ? 502 SER B OG  1 
ATOM   10060 N  N   . ILE B 1 503 ? 227.474 227.081 201.465 1.00 45.47  ? 503 ILE B N   1 
ATOM   10061 C  CA  . ILE B 1 503 ? 227.959 226.488 200.225 1.00 39.31  ? 503 ILE B CA  1 
ATOM   10062 C  C   . ILE B 1 503 ? 229.283 227.130 199.855 1.00 34.75  ? 503 ILE B C   1 
ATOM   10063 O  O   . ILE B 1 503 ? 229.393 228.361 199.780 1.00 45.17  ? 503 ILE B O   1 
ATOM   10064 C  CB  . ILE B 1 503 ? 226.941 226.642 199.089 1.00 41.77  ? 503 ILE B CB  1 
ATOM   10065 C  CG1 . ILE B 1 503 ? 225.528 226.419 199.620 1.00 48.32  ? 503 ILE B CG1 1 
ATOM   10066 C  CG2 . ILE B 1 503 ? 227.250 225.678 197.972 1.00 46.15  ? 503 ILE B CG2 1 
ATOM   10067 C  CD1 . ILE B 1 503 ? 224.471 226.446 198.555 1.00 59.57  ? 503 ILE B CD1 1 
ATOM   10068 N  N   . GLY B 1 504 ? 230.292 226.294 199.637 1.00 35.01  ? 504 GLY B N   1 
ATOM   10069 C  CA  . GLY B 1 504 ? 231.584 226.749 199.174 1.00 37.29  ? 504 GLY B CA  1 
ATOM   10070 C  C   . GLY B 1 504 ? 231.836 226.229 197.774 1.00 40.89  ? 504 GLY B C   1 
ATOM   10071 O  O   . GLY B 1 504 ? 231.807 225.022 197.536 1.00 49.02  ? 504 GLY B O   1 
ATOM   10072 N  N   . ILE B 1 505 ? 232.085 227.150 196.856 1.00 40.50  ? 505 ILE B N   1 
ATOM   10073 C  CA  . ILE B 1 505 ? 232.236 226.834 195.444 1.00 41.37  ? 505 ILE B CA  1 
ATOM   10074 C  C   . ILE B 1 505 ? 233.699 226.970 195.077 1.00 41.11  ? 505 ILE B C   1 
ATOM   10075 O  O   . ILE B 1 505 ? 234.336 227.975 195.408 1.00 51.15  ? 505 ILE B O   1 
ATOM   10076 C  CB  . ILE B 1 505 ? 231.367 227.751 194.567 1.00 46.47  ? 505 ILE B CB  1 
ATOM   10077 C  CG1 . ILE B 1 505 ? 229.926 227.749 195.076 1.00 46.69  ? 505 ILE B CG1 1 
ATOM   10078 C  CG2 . ILE B 1 505 ? 231.460 227.330 193.122 1.00 47.95  ? 505 ILE B CG2 1 
ATOM   10079 C  CD1 . ILE B 1 505 ? 228.898 228.058 194.037 1.00 51.49  ? 505 ILE B CD1 1 
ATOM   10080 N  N   . SER B 1 506 ? 234.228 225.969 194.404 1.00 38.69  ? 506 SER B N   1 
ATOM   10081 C  CA  . SER B 1 506 ? 235.600 225.998 193.937 1.00 48.34  ? 506 SER B CA  1 
ATOM   10082 C  C   . SER B 1 506 ? 235.647 225.578 192.481 1.00 56.16  ? 506 SER B C   1 
ATOM   10083 O  O   . SER B 1 506 ? 235.004 224.599 192.085 1.00 59.27  ? 506 SER B O   1 
ATOM   10084 C  CB  . SER B 1 506 ? 236.485 225.076 194.762 1.00 61.49  ? 506 SER B CB  1 
ATOM   10085 O  OG  . SER B 1 506 ? 237.814 225.083 194.273 1.00 69.71  ? 506 SER B OG  1 
ATOM   10086 N  N   . TYR B 1 507 ? 236.410 226.322 191.686 1.00 59.37  ? 507 TYR B N   1 
ATOM   10087 C  CA  . TYR B 1 507 ? 236.558 226.002 190.272 1.00 64.35  ? 507 TYR B CA  1 
ATOM   10088 C  C   . TYR B 1 507 ? 237.837 226.639 189.767 1.00 69.43  ? 507 TYR B C   1 
ATOM   10089 O  O   . TYR B 1 507 ? 237.924 227.867 189.678 1.00 71.80  ? 507 TYR B O   1 
ATOM   10090 C  CB  . TYR B 1 507 ? 235.358 226.489 189.477 1.00 65.29  ? 507 TYR B CB  1 
ATOM   10091 C  CG  . TYR B 1 507 ? 235.680 226.899 188.066 1.00 69.09  ? 507 TYR B CG  1 
ATOM   10092 C  CD1 . TYR B 1 507 ? 236.023 225.957 187.110 1.00 72.16  ? 507 TYR B CD1 1 
ATOM   10093 C  CD2 . TYR B 1 507 ? 235.636 228.228 187.691 1.00 75.20  ? 507 TYR B CD2 1 
ATOM   10094 C  CE1 . TYR B 1 507 ? 236.318 226.332 185.815 1.00 77.98  ? 507 TYR B CE1 1 
ATOM   10095 C  CE2 . TYR B 1 507 ? 235.926 228.615 186.402 1.00 81.43  ? 507 TYR B CE2 1 
ATOM   10096 C  CZ  . TYR B 1 507 ? 236.268 227.665 185.466 1.00 83.37  ? 507 TYR B CZ  1 
ATOM   10097 O  OH  . TYR B 1 507 ? 236.556 228.051 184.178 1.00 85.50  ? 507 TYR B OH  1 
ATOM   10098 N  N   . ASP B 1 508 ? 238.830 225.816 189.463 1.00 71.77  ? 508 ASP B N   1 
ATOM   10099 C  CA  . ASP B 1 508 ? 240.062 226.304 188.871 1.00 76.80  ? 508 ASP B CA  1 
ATOM   10100 C  C   . ASP B 1 508 ? 240.522 225.284 187.846 1.00 80.41  ? 508 ASP B C   1 
ATOM   10101 O  O   . ASP B 1 508 ? 240.263 224.086 187.975 1.00 81.34  ? 508 ASP B O   1 
ATOM   10102 C  CB  . ASP B 1 508 ? 241.145 226.548 189.924 1.00 80.79  ? 508 ASP B CB  1 
ATOM   10103 C  CG  . ASP B 1 508 ? 240.596 227.174 191.191 1.00 82.68  ? 508 ASP B CG  1 
ATOM   10104 O  OD1 . ASP B 1 508 ? 239.885 226.473 191.942 1.00 82.29  ? 508 ASP B OD1 1 
ATOM   10105 O  OD2 . ASP B 1 508 ? 240.870 228.368 191.432 1.00 85.53  ? 508 ASP B OD2 1 
ATOM   10106 N  N   . LEU B 1 509 ? 241.216 225.774 186.830 1.00 80.36  ? 509 LEU B N   1 
ATOM   10107 C  CA  . LEU B 1 509 ? 241.577 224.960 185.682 1.00 82.08  ? 509 LEU B CA  1 
ATOM   10108 C  C   . LEU B 1 509 ? 242.850 224.177 185.968 1.00 85.01  ? 509 LEU B C   1 
ATOM   10109 O  O   . LEU B 1 509 ? 243.814 224.723 186.514 1.00 86.39  ? 509 LEU B O   1 
ATOM   10110 C  CB  . LEU B 1 509 ? 241.765 225.836 184.445 1.00 80.71  ? 509 LEU B CB  1 
ATOM   10111 C  CG  . LEU B 1 509 ? 240.523 226.110 183.595 1.00 77.23  ? 509 LEU B CG  1 
ATOM   10112 C  CD1 . LEU B 1 509 ? 239.929 224.810 183.086 1.00 78.29  ? 509 LEU B CD1 1 
ATOM   10113 C  CD2 . LEU B 1 509 ? 239.498 226.891 184.380 1.00 74.95  ? 509 LEU B CD2 1 
ATOM   10114 N  N   . GLY B 1 510 ? 242.848 222.899 185.598 1.00 85.01  ? 510 GLY B N   1 
ATOM   10115 C  CA  . GLY B 1 510 ? 244.055 222.103 185.676 1.00 88.18  ? 510 GLY B CA  1 
ATOM   10116 C  C   . GLY B 1 510 ? 244.506 221.753 187.073 1.00 92.08  ? 510 GLY B C   1 
ATOM   10117 O  O   . GLY B 1 510 ? 245.689 221.471 187.279 1.00 93.80  ? 510 GLY B O   1 
ATOM   10118 N  N   . LYS B 1 511 ? 243.599 221.759 188.042 1.00 92.57  ? 511 LYS B N   1 
ATOM   10119 C  CA  . LYS B 1 511 ? 243.922 221.426 189.419 1.00 94.58  ? 511 LYS B CA  1 
ATOM   10120 C  C   . LYS B 1 511 ? 243.242 220.122 189.809 1.00 98.20  ? 511 LYS B C   1 
ATOM   10121 O  O   . LYS B 1 511 ? 242.094 219.872 189.430 1.00 97.58  ? 511 LYS B O   1 
ATOM   10122 C  CB  . LYS B 1 511 ? 243.497 222.552 190.359 1.00 90.09  ? 511 LYS B CB  1 
ATOM   10123 C  CG  . LYS B 1 511 ? 243.594 223.924 189.726 1.00 88.36  ? 511 LYS B CG  1 
ATOM   10124 C  CD  . LYS B 1 511 ? 245.044 224.317 189.496 1.00 90.53  ? 511 LYS B CD  1 
ATOM   10125 C  CE  . LYS B 1 511 ? 245.816 224.357 190.804 1.00 90.42  ? 511 LYS B CE  1 
ATOM   10126 N  NZ  . LYS B 1 511 ? 247.105 225.089 190.669 1.00 89.94  ? 511 LYS B NZ  1 
ATOM   10127 N  N   . ASN B 1 512 ? 243.956 219.295 190.568 1.00 98.48  ? 512 ASN B N   1 
ATOM   10128 C  CA  . ASN B 1 512 ? 243.456 217.975 190.916 1.00 94.43  ? 512 ASN B CA  1 
ATOM   10129 C  C   . ASN B 1 512 ? 242.352 218.093 191.966 1.00 92.90  ? 512 ASN B C   1 
ATOM   10130 O  O   . ASN B 1 512 ? 241.989 219.183 192.411 1.00 91.72  ? 512 ASN B O   1 
ATOM   10131 C  CB  . ASN B 1 512 ? 244.598 217.091 191.405 1.00 93.58  ? 512 ASN B CB  1 
ATOM   10132 C  CG  . ASN B 1 512 ? 244.770 217.139 192.902 1.00 95.55  ? 512 ASN B CG  1 
ATOM   10133 O  OD1 . ASN B 1 512 ? 244.069 216.445 193.635 1.00 95.20  ? 512 ASN B OD1 1 
ATOM   10134 N  ND2 . ASN B 1 512 ? 245.690 217.971 193.369 1.00 95.48  ? 512 ASN B ND2 1 
ATOM   10135 N  N   . ARG B 1 513 ? 241.813 216.943 192.373 1.00 91.41  ? 513 ARG B N   1 
ATOM   10136 C  CA  . ARG B 1 513 ? 240.600 216.948 193.182 1.00 89.30  ? 513 ARG B CA  1 
ATOM   10137 C  C   . ARG B 1 513 ? 240.852 217.320 194.637 1.00 89.98  ? 513 ARG B C   1 
ATOM   10138 O  O   . ARG B 1 513 ? 239.966 217.904 195.275 1.00 90.50  ? 513 ARG B O   1 
ATOM   10139 C  CB  . ARG B 1 513 ? 239.902 215.589 193.117 1.00 84.75  ? 513 ARG B CB  1 
ATOM   10140 C  CG  . ARG B 1 513 ? 240.469 214.537 194.047 1.00 85.45  ? 513 ARG B CG  1 
ATOM   10141 C  CD  . ARG B 1 513 ? 239.437 213.464 194.340 1.00 83.48  ? 513 ARG B CD  1 
ATOM   10142 N  NE  . ARG B 1 513 ? 239.688 212.800 195.614 1.00 81.90  ? 513 ARG B NE  1 
ATOM   10143 C  CZ  . ARG B 1 513 ? 240.516 211.780 195.777 1.00 80.47  ? 513 ARG B CZ  1 
ATOM   10144 N  NH1 . ARG B 1 513 ? 241.190 211.267 194.761 1.00 81.70  ? 513 ARG B NH1 1 
ATOM   10145 N  NH2 . ARG B 1 513 ? 240.671 211.259 196.990 1.00 78.30  ? 513 ARG B NH2 1 
ATOM   10146 N  N   . ASP B 1 514 ? 242.020 216.986 195.193 1.00 90.07  ? 514 ASP B N   1 
ATOM   10147 C  CA  . ASP B 1 514 ? 242.238 217.263 196.609 1.00 91.50  ? 514 ASP B CA  1 
ATOM   10148 C  C   . ASP B 1 514 ? 242.203 218.760 196.873 1.00 87.97  ? 514 ASP B C   1 
ATOM   10149 O  O   . ASP B 1 514 ? 241.635 219.212 197.873 1.00 81.96  ? 514 ASP B O   1 
ATOM   10150 C  CB  . ASP B 1 514 ? 243.556 216.650 197.088 1.00 93.87  ? 514 ASP B CB  1 
ATOM   10151 C  CG  . ASP B 1 514 ? 244.772 217.183 196.344 1.00 97.92  ? 514 ASP B CG  1 
ATOM   10152 O  OD1 . ASP B 1 514 ? 244.669 218.218 195.652 1.00 97.70  ? 514 ASP B OD1 1 
ATOM   10153 O  OD2 . ASP B 1 514 ? 245.847 216.557 196.455 1.00 100.83 ? 514 ASP B OD2 1 
ATOM   10154 N  N   . TYR B 1 515 ? 242.793 219.544 195.970 1.00 89.27  ? 515 TYR B N   1 
ATOM   10155 C  CA  . TYR B 1 515 ? 242.763 220.993 196.108 1.00 84.96  ? 515 TYR B CA  1 
ATOM   10156 C  C   . TYR B 1 515 ? 241.334 221.511 196.071 1.00 83.64  ? 515 TYR B C   1 
ATOM   10157 O  O   . TYR B 1 515 ? 240.944 222.346 196.895 1.00 83.02  ? 515 TYR B O   1 
ATOM   10158 C  CB  . TYR B 1 515 ? 243.598 221.634 195.002 1.00 84.79  ? 515 TYR B CB  1 
ATOM   10159 C  CG  . TYR B 1 515 ? 243.310 223.097 194.770 1.00 82.88  ? 515 TYR B CG  1 
ATOM   10160 C  CD1 . TYR B 1 515 ? 243.887 224.069 195.571 1.00 85.14  ? 515 TYR B CD1 1 
ATOM   10161 C  CD2 . TYR B 1 515 ? 242.475 223.507 193.743 1.00 81.90  ? 515 TYR B CD2 1 
ATOM   10162 C  CE1 . TYR B 1 515 ? 243.638 225.406 195.360 1.00 87.68  ? 515 TYR B CE1 1 
ATOM   10163 C  CE2 . TYR B 1 515 ? 242.217 224.842 193.527 1.00 85.50  ? 515 TYR B CE2 1 
ATOM   10164 C  CZ  . TYR B 1 515 ? 242.800 225.788 194.339 1.00 87.42  ? 515 TYR B CZ  1 
ATOM   10165 O  OH  . TYR B 1 515 ? 242.545 227.123 194.127 1.00 82.60  ? 515 TYR B OH  1 
ATOM   10166 N  N   . LEU B 1 516 ? 240.537 221.028 195.115 1.00 82.17  ? 516 LEU B N   1 
ATOM   10167 C  CA  . LEU B 1 516 ? 239.161 221.496 195.006 1.00 78.49  ? 516 LEU B CA  1 
ATOM   10168 C  C   . LEU B 1 516 ? 238.383 221.183 196.271 1.00 78.26  ? 516 LEU B C   1 
ATOM   10169 O  O   . LEU B 1 516 ? 237.674 222.043 196.806 1.00 79.20  ? 516 LEU B O   1 
ATOM   10170 C  CB  . LEU B 1 516 ? 238.479 220.876 193.791 1.00 72.70  ? 516 LEU B CB  1 
ATOM   10171 C  CG  . LEU B 1 516 ? 239.092 221.239 192.444 1.00 75.38  ? 516 LEU B CG  1 
ATOM   10172 C  CD1 . LEU B 1 516 ? 238.425 220.461 191.325 1.00 73.44  ? 516 LEU B CD1 1 
ATOM   10173 C  CD2 . LEU B 1 516 ? 238.969 222.731 192.207 1.00 76.35  ? 516 LEU B CD2 1 
ATOM   10174 N  N   . LEU B 1 517 ? 238.528 219.962 196.787 1.00 76.02  ? 517 LEU B N   1 
ATOM   10175 C  CA  . LEU B 1 517 ? 237.813 219.604 198.005 1.00 80.09  ? 517 LEU B CA  1 
ATOM   10176 C  C   . LEU B 1 517 ? 238.289 220.433 199.194 1.00 83.61  ? 517 LEU B C   1 
ATOM   10177 O  O   . LEU B 1 517 ? 237.477 220.865 200.024 1.00 83.45  ? 517 LEU B O   1 
ATOM   10178 C  CB  . LEU B 1 517 ? 237.966 218.111 198.277 1.00 81.91  ? 517 LEU B CB  1 
ATOM   10179 C  CG  . LEU B 1 517 ? 237.135 217.239 197.337 1.00 82.96  ? 517 LEU B CG  1 
ATOM   10180 C  CD1 . LEU B 1 517 ? 237.676 215.818 197.301 1.00 80.97  ? 517 LEU B CD1 1 
ATOM   10181 C  CD2 . LEU B 1 517 ? 235.678 217.250 197.756 1.00 76.01  ? 517 LEU B CD2 1 
ATOM   10182 N  N   . SER B 1 518 ? 239.597 220.683 199.284 1.00 83.42  ? 518 SER B N   1 
ATOM   10183 C  CA  . SER B 1 518 ? 240.132 221.435 200.414 1.00 80.40  ? 518 SER B CA  1 
ATOM   10184 C  C   . SER B 1 518 ? 239.614 222.866 200.422 1.00 77.95  ? 518 SER B C   1 
ATOM   10185 O  O   . SER B 1 518 ? 239.137 223.359 201.451 1.00 77.00  ? 518 SER B O   1 
ATOM   10186 C  CB  . SER B 1 518 ? 241.657 221.416 200.372 1.00 81.47  ? 518 SER B CB  1 
ATOM   10187 O  OG  . SER B 1 518 ? 242.122 221.736 199.076 1.00 81.61  ? 518 SER B OG  1 
ATOM   10188 N  N   . THR B 1 519 ? 239.695 223.552 199.280 1.00 79.06  ? 519 THR B N   1 
ATOM   10189 C  CA  . THR B 1 519 ? 239.182 224.917 199.233 1.00 77.69  ? 519 THR B CA  1 
ATOM   10190 C  C   . THR B 1 519 ? 237.672 224.961 199.388 1.00 72.36  ? 519 THR B C   1 
ATOM   10191 O  O   . THR B 1 519 ? 237.143 225.908 199.984 1.00 71.96  ? 519 THR B O   1 
ATOM   10192 C  CB  . THR B 1 519 ? 239.593 225.617 197.941 1.00 78.57  ? 519 THR B CB  1 
ATOM   10193 O  OG1 . THR B 1 519 ? 238.669 225.285 196.901 1.00 75.81  ? 519 THR B OG1 1 
ATOM   10194 C  CG2 . THR B 1 519 ? 241.004 225.255 197.544 1.00 80.63  ? 519 THR B CG2 1 
ATOM   10195 N  N   . ALA B 1 520 ? 236.958 223.953 198.884 1.00 67.40  ? 520 ALA B N   1 
ATOM   10196 C  CA  . ALA B 1 520 ? 235.521 223.918 199.100 1.00 63.19  ? 520 ALA B CA  1 
ATOM   10197 C  C   . ALA B 1 520 ? 235.195 223.842 200.583 1.00 64.37  ? 520 ALA B C   1 
ATOM   10198 O  O   . ALA B 1 520 ? 234.324 224.573 201.074 1.00 64.75  ? 520 ALA B O   1 
ATOM   10199 C  CB  . ALA B 1 520 ? 234.910 222.739 198.347 1.00 63.16  ? 520 ALA B CB  1 
ATOM   10200 N  N   . HIS B 1 521 ? 235.899 222.983 201.322 1.00 67.97  ? 521 HIS B N   1 
ATOM   10201 C  CA  . HIS B 1 521 ? 235.631 222.888 202.753 1.00 68.48  ? 521 HIS B CA  1 
ATOM   10202 C  C   . HIS B 1 521 ? 236.050 224.153 203.483 1.00 72.64  ? 521 HIS B C   1 
ATOM   10203 O  O   . HIS B 1 521 ? 235.395 224.560 204.449 1.00 72.32  ? 521 HIS B O   1 
ATOM   10204 C  CB  . HIS B 1 521 ? 236.329 221.685 203.367 1.00 69.99  ? 521 HIS B CB  1 
ATOM   10205 C  CG  . HIS B 1 521 ? 235.999 221.494 204.812 1.00 70.95  ? 521 HIS B CG  1 
ATOM   10206 N  ND1 . HIS B 1 521 ? 234.867 220.834 205.234 1.00 70.01  ? 521 HIS B ND1 1 
ATOM   10207 C  CD2 . HIS B 1 521 ? 236.637 221.902 205.933 1.00 70.64  ? 521 HIS B CD2 1 
ATOM   10208 C  CE1 . HIS B 1 521 ? 234.829 220.830 206.554 1.00 68.42  ? 521 HIS B CE1 1 
ATOM   10209 N  NE2 . HIS B 1 521 ? 235.892 221.470 207.003 1.00 69.98  ? 521 HIS B NE2 1 
ATOM   10210 N  N   . ASN B 1 522 ? 237.150 224.777 203.056 1.00 76.57  ? 522 ASN B N   1 
ATOM   10211 C  CA  . ASN B 1 522 ? 237.573 226.020 203.693 1.00 74.37  ? 522 ASN B CA  1 
ATOM   10212 C  C   . ASN B 1 522 ? 236.517 227.103 203.528 1.00 68.48  ? 522 ASN B C   1 
ATOM   10213 O  O   . ASN B 1 522 ? 236.186 227.810 204.487 1.00 68.22  ? 522 ASN B O   1 
ATOM   10214 C  CB  . ASN B 1 522 ? 238.910 226.478 203.118 1.00 75.89  ? 522 ASN B CB  1 
ATOM   10215 C  CG  . ASN B 1 522 ? 239.250 227.899 203.503 1.00 78.50  ? 522 ASN B CG  1 
ATOM   10216 O  OD1 . ASN B 1 522 ? 239.026 228.832 202.734 1.00 76.91  ? 522 ASN B OD1 1 
ATOM   10217 N  ND2 . ASN B 1 522 ? 239.790 228.073 204.703 1.00 82.32  ? 522 ASN B ND2 1 
ATOM   10218 N  N   . ALA B 1 523 ? 235.957 227.229 202.324 1.00 62.35  ? 523 ALA B N   1 
ATOM   10219 C  CA  . ALA B 1 523 ? 234.893 228.201 202.108 1.00 57.17  ? 523 ALA B CA  1 
ATOM   10220 C  C   . ALA B 1 523 ? 233.653 227.866 202.927 1.00 57.52  ? 523 ALA B C   1 
ATOM   10221 O  O   . ALA B 1 523 ? 233.032 228.760 203.523 1.00 63.95  ? 523 ALA B O   1 
ATOM   10222 C  CB  . ALA B 1 523 ? 234.557 228.278 200.624 1.00 53.15  ? 523 ALA B CB  1 
ATOM   10223 N  N   . MET B 1 524 ? 233.270 226.589 202.973 1.00 55.98  ? 524 MET B N   1 
ATOM   10224 C  CA  . MET B 1 524 ? 232.098 226.206 203.753 1.00 55.75  ? 524 MET B CA  1 
ATOM   10225 C  C   . MET B 1 524 ? 232.282 226.553 205.221 1.00 64.07  ? 524 MET B C   1 
ATOM   10226 O  O   . MET B 1 524 ? 231.378 227.100 205.862 1.00 66.92  ? 524 MET B O   1 
ATOM   10227 C  CB  . MET B 1 524 ? 231.828 224.715 203.599 1.00 57.08  ? 524 MET B CB  1 
ATOM   10228 C  CG  . MET B 1 524 ? 230.418 224.309 203.933 1.00 57.31  ? 524 MET B CG  1 
ATOM   10229 S  SD  . MET B 1 524 ? 230.302 223.783 205.647 1.00 74.65  ? 524 MET B SD  1 
ATOM   10230 C  CE  . MET B 1 524 ? 230.581 222.025 205.494 1.00 62.05  ? 524 MET B CE  1 
ATOM   10231 N  N   . ASP B 1 525 ? 233.455 226.242 205.770 1.00 69.30  ? 525 ASP B N   1 
ATOM   10232 C  CA  . ASP B 1 525 ? 233.728 226.546 207.168 1.00 71.14  ? 525 ASP B CA  1 
ATOM   10233 C  C   . ASP B 1 525 ? 233.736 228.047 207.410 1.00 67.87  ? 525 ASP B C   1 
ATOM   10234 O  O   . ASP B 1 525 ? 233.257 228.514 208.447 1.00 67.48  ? 525 ASP B O   1 
ATOM   10235 C  CB  . ASP B 1 525 ? 235.061 225.924 207.583 1.00 74.81  ? 525 ASP B CB  1 
ATOM   10236 C  CG  . ASP B 1 525 ? 235.514 226.373 208.958 1.00 80.55  ? 525 ASP B CG  1 
ATOM   10237 O  OD1 . ASP B 1 525 ? 234.677 226.394 209.885 1.00 78.53  ? 525 ASP B OD1 1 
ATOM   10238 O  OD2 . ASP B 1 525 ? 236.709 226.700 209.112 1.00 84.23  ? 525 ASP B OD2 1 
ATOM   10239 N  N   . TYR B 1 526 ? 234.291 228.817 206.472 1.00 65.38  ? 526 TYR B N   1 
ATOM   10240 C  CA  . TYR B 1 526 ? 234.324 230.266 206.628 1.00 62.77  ? 526 TYR B CA  1 
ATOM   10241 C  C   . TYR B 1 526 ? 232.911 230.820 206.728 1.00 61.80  ? 526 TYR B C   1 
ATOM   10242 O  O   . TYR B 1 526 ? 232.600 231.621 207.621 1.00 65.21  ? 526 TYR B O   1 
ATOM   10243 C  CB  . TYR B 1 526 ? 235.096 230.874 205.454 1.00 64.12  ? 526 TYR B CB  1 
ATOM   10244 C  CG  . TYR B 1 526 ? 234.902 232.349 205.199 1.00 69.14  ? 526 TYR B CG  1 
ATOM   10245 C  CD1 . TYR B 1 526 ? 233.774 232.831 204.549 1.00 71.09  ? 526 TYR B CD1 1 
ATOM   10246 C  CD2 . TYR B 1 526 ? 235.881 233.260 205.568 1.00 72.34  ? 526 TYR B CD2 1 
ATOM   10247 C  CE1 . TYR B 1 526 ? 233.611 234.181 204.311 1.00 76.20  ? 526 TYR B CE1 1 
ATOM   10248 C  CE2 . TYR B 1 526 ? 235.730 234.608 205.330 1.00 74.99  ? 526 TYR B CE2 1 
ATOM   10249 C  CZ  . TYR B 1 526 ? 234.594 235.065 204.701 1.00 78.31  ? 526 TYR B CZ  1 
ATOM   10250 O  OH  . TYR B 1 526 ? 234.438 236.411 204.460 1.00 77.28  ? 526 TYR B OH  1 
ATOM   10251 N  N   . ILE B 1 527 ? 232.026 230.364 205.842 1.00 60.77  ? 527 ILE B N   1 
ATOM   10252 C  CA  . ILE B 1 527 ? 230.640 230.819 205.884 1.00 59.69  ? 527 ILE B CA  1 
ATOM   10253 C  C   . ILE B 1 527 ? 229.960 230.371 207.172 1.00 64.32  ? 527 ILE B C   1 
ATOM   10254 O  O   . ILE B 1 527 ? 229.203 231.132 207.786 1.00 68.26  ? 527 ILE B O   1 
ATOM   10255 C  CB  . ILE B 1 527 ? 229.877 230.331 204.643 1.00 59.33  ? 527 ILE B CB  1 
ATOM   10256 C  CG1 . ILE B 1 527 ? 230.415 231.026 203.401 1.00 54.96  ? 527 ILE B CG1 1 
ATOM   10257 C  CG2 . ILE B 1 527 ? 228.397 230.594 204.798 1.00 57.79  ? 527 ILE B CG2 1 
ATOM   10258 C  CD1 . ILE B 1 527 ? 230.344 232.510 203.483 1.00 57.18  ? 527 ILE B CD1 1 
ATOM   10259 N  N   . ARG B 1 528 ? 230.203 229.129 207.597 1.00 66.37  ? 528 ARG B N   1 
ATOM   10260 C  CA  . ARG B 1 528 ? 229.559 228.629 208.809 1.00 69.22  ? 528 ARG B CA  1 
ATOM   10261 C  C   . ARG B 1 528 ? 229.971 229.445 210.026 1.00 71.60  ? 528 ARG B C   1 
ATOM   10262 O  O   . ARG B 1 528 ? 229.127 229.842 210.838 1.00 69.46  ? 528 ARG B O   1 
ATOM   10263 C  CB  . ARG B 1 528 ? 229.907 227.156 209.025 1.00 69.29  ? 528 ARG B CB  1 
ATOM   10264 C  CG  . ARG B 1 528 ? 229.050 226.177 208.252 1.00 71.47  ? 528 ARG B CG  1 
ATOM   10265 C  CD  . ARG B 1 528 ? 229.096 224.796 208.889 1.00 78.74  ? 528 ARG B CD  1 
ATOM   10266 N  NE  . ARG B 1 528 ? 228.177 224.686 210.016 1.00 83.50  ? 528 ARG B NE  1 
ATOM   10267 C  CZ  . ARG B 1 528 ? 228.278 223.784 210.982 1.00 85.09  ? 528 ARG B CZ  1 
ATOM   10268 N  NH1 . ARG B 1 528 ? 229.260 222.897 211.000 1.00 82.93  ? 528 ARG B NH1 1 
ATOM   10269 N  NH2 . ARG B 1 528 ? 227.371 223.770 211.955 1.00 84.42  ? 528 ARG B NH2 1 
ATOM   10270 N  N   . LYS B 1 529 ? 231.272 229.702 210.168 1.00 72.89  ? 529 LYS B N   1 
ATOM   10271 C  CA  . LYS B 1 529 ? 231.764 230.441 211.325 1.00 71.59  ? 529 LYS B CA  1 
ATOM   10272 C  C   . LYS B 1 529 ? 231.264 231.875 211.316 1.00 66.64  ? 529 LYS B C   1 
ATOM   10273 O  O   . LYS B 1 529 ? 230.862 232.403 212.358 1.00 65.85  ? 529 LYS B O   1 
ATOM   10274 C  CB  . LYS B 1 529 ? 233.291 230.413 211.362 1.00 73.18  ? 529 LYS B CB  1 
ATOM   10275 C  CG  . LYS B 1 529 ? 233.886 229.148 211.952 1.00 76.91  ? 529 LYS B CG  1 
ATOM   10276 C  CD  . LYS B 1 529 ? 235.404 229.175 211.869 1.00 79.15  ? 529 LYS B CD  1 
ATOM   10277 C  CE  . LYS B 1 529 ? 236.021 227.987 212.588 1.00 82.25  ? 529 LYS B CE  1 
ATOM   10278 N  NZ  . LYS B 1 529 ? 237.428 227.753 212.160 1.00 82.39  ? 529 LYS B NZ  1 
ATOM   10279 N  N   . ASN B 1 530 ? 231.264 232.519 210.151 1.00 63.99  ? 530 ASN B N   1 
ATOM   10280 C  CA  . ASN B 1 530 ? 230.835 233.908 210.110 1.00 63.69  ? 530 ASN B CA  1 
ATOM   10281 C  C   . ASN B 1 530 ? 229.333 234.072 210.278 1.00 66.96  ? 530 ASN B C   1 
ATOM   10282 O  O   . ASN B 1 530 ? 228.865 235.209 210.384 1.00 73.18  ? 530 ASN B O   1 
ATOM   10283 C  CB  . ASN B 1 530 ? 231.293 234.544 208.805 1.00 64.60  ? 530 ASN B CB  1 
ATOM   10284 C  CG  . ASN B 1 530 ? 232.795 234.721 208.748 1.00 70.44  ? 530 ASN B CG  1 
ATOM   10285 O  OD1 . ASN B 1 530 ? 233.431 235.020 209.757 1.00 71.29  ? 530 ASN B OD1 1 
ATOM   10286 N  ND2 . ASN B 1 530 ? 233.373 234.529 207.569 1.00 70.83  ? 530 ASN B ND2 1 
ATOM   10287 N  N   . GLY B 1 531 ? 228.568 232.985 210.301 1.00 65.63  ? 531 GLY B N   1 
ATOM   10288 C  CA  . GLY B 1 531 ? 227.139 233.082 210.524 1.00 65.27  ? 531 GLY B CA  1 
ATOM   10289 C  C   . GLY B 1 531 ? 226.288 232.118 209.722 1.00 68.93  ? 531 GLY B C   1 
ATOM   10290 O  O   . GLY B 1 531 ? 225.153 231.824 210.108 1.00 70.37  ? 531 GLY B O   1 
ATOM   10291 N  N   . GLY B 1 532 ? 226.817 231.614 208.611 1.00 72.51  ? 532 GLY B N   1 
ATOM   10292 C  CA  . GLY B 1 532 ? 226.093 230.650 207.810 1.00 70.16  ? 532 GLY B CA  1 
ATOM   10293 C  C   . GLY B 1 532 ? 225.014 231.277 206.945 1.00 69.57  ? 532 GLY B C   1 
ATOM   10294 O  O   . GLY B 1 532 ? 224.895 232.498 206.814 1.00 72.82  ? 532 GLY B O   1 
ATOM   10295 N  N   . ASN B 1 533 ? 224.211 230.397 206.344 1.00 67.79  ? 533 ASN B N   1 
ATOM   10296 C  CA  . ASN B 1 533 ? 223.145 230.779 205.418 1.00 67.46  ? 533 ASN B CA  1 
ATOM   10297 C  C   . ASN B 1 533 ? 223.688 231.628 204.271 1.00 63.85  ? 533 ASN B C   1 
ATOM   10298 O  O   . ASN B 1 533 ? 223.354 232.800 204.117 1.00 67.87  ? 533 ASN B O   1 
ATOM   10299 C  CB  . ASN B 1 533 ? 222.014 231.506 206.143 1.00 74.10  ? 533 ASN B CB  1 
ATOM   10300 C  CG  . ASN B 1 533 ? 220.821 231.745 205.253 1.00 81.34  ? 533 ASN B CG  1 
ATOM   10301 O  OD1 . ASN B 1 533 ? 220.222 230.805 204.736 1.00 74.91  ? 533 ASN B OD1 1 
ATOM   10302 N  ND2 . ASN B 1 533 ? 220.465 233.008 205.068 1.00 87.38  ? 533 ASN B ND2 1 
ATOM   10303 N  N   . GLY B 1 534 ? 224.536 231.012 203.459 1.00 58.68  ? 534 GLY B N   1 
ATOM   10304 C  CA  . GLY B 1 534 ? 225.122 231.747 202.359 1.00 51.99  ? 534 GLY B CA  1 
ATOM   10305 C  C   . GLY B 1 534 ? 226.057 230.879 201.552 1.00 48.31  ? 534 GLY B C   1 
ATOM   10306 O  O   . GLY B 1 534 ? 226.123 229.663 201.729 1.00 53.13  ? 534 GLY B O   1 
ATOM   10307 N  N   . TRP B 1 535 ? 226.788 231.532 200.656 1.00 40.96  ? 535 TRP B N   1 
ATOM   10308 C  CA  . TRP B 1 535 ? 227.694 230.816 199.780 1.00 42.70  ? 535 TRP B CA  1 
ATOM   10309 C  C   . TRP B 1 535 ? 228.836 231.737 199.398 1.00 38.86  ? 535 TRP B C   1 
ATOM   10310 O  O   . TRP B 1 535 ? 228.751 232.953 199.550 1.00 44.22  ? 535 TRP B O   1 
ATOM   10311 C  CB  . TRP B 1 535 ? 226.971 230.288 198.536 1.00 49.99  ? 535 TRP B CB  1 
ATOM   10312 C  CG  . TRP B 1 535 ? 226.292 231.348 197.720 1.00 55.15  ? 535 TRP B CG  1 
ATOM   10313 C  CD1 . TRP B 1 535 ? 225.087 231.931 197.970 1.00 57.32  ? 535 TRP B CD1 1 
ATOM   10314 C  CD2 . TRP B 1 535 ? 226.774 231.927 196.507 1.00 53.00  ? 535 TRP B CD2 1 
ATOM   10315 N  NE1 . TRP B 1 535 ? 224.799 232.854 196.997 1.00 51.42  ? 535 TRP B NE1 1 
ATOM   10316 C  CE2 . TRP B 1 535 ? 225.821 232.868 196.086 1.00 48.90  ? 535 TRP B CE2 1 
ATOM   10317 C  CE3 . TRP B 1 535 ? 227.925 231.750 195.743 1.00 51.70  ? 535 TRP B CE3 1 
ATOM   10318 C  CZ2 . TRP B 1 535 ? 225.984 233.622 194.937 1.00 52.19  ? 535 TRP B CZ2 1 
ATOM   10319 C  CZ3 . TRP B 1 535 ? 228.084 232.500 194.606 1.00 50.50  ? 535 TRP B CZ3 1 
ATOM   10320 C  CH2 . TRP B 1 535 ? 227.123 233.423 194.211 1.00 52.14  ? 535 TRP B CH2 1 
ATOM   10321 N  N   . GLN B 1 536 ? 229.914 231.137 198.912 1.00 38.91  ? 536 GLN B N   1 
ATOM   10322 C  CA  . GLN B 1 536 ? 231.101 231.917 198.608 1.00 38.99  ? 536 GLN B CA  1 
ATOM   10323 C  C   . GLN B 1 536 ? 232.046 231.094 197.758 1.00 44.54  ? 536 GLN B C   1 
ATOM   10324 O  O   . GLN B 1 536 ? 232.090 229.867 197.874 1.00 54.77  ? 536 GLN B O   1 
ATOM   10325 C  CB  . GLN B 1 536 ? 231.800 232.366 199.895 1.00 47.40  ? 536 GLN B CB  1 
ATOM   10326 C  CG  . GLN B 1 536 ? 233.094 233.114 199.685 1.00 59.87  ? 536 GLN B CG  1 
ATOM   10327 C  CD  . GLN B 1 536 ? 233.486 233.937 200.885 1.00 67.49  ? 536 GLN B CD  1 
ATOM   10328 O  OE1 . GLN B 1 536 ? 232.687 234.709 201.410 1.00 68.24  ? 536 GLN B OE1 1 
ATOM   10329 N  NE2 . GLN B 1 536 ? 234.727 233.780 201.329 1.00 67.36  ? 536 GLN B NE2 1 
ATOM   10330 N  N   . PHE B 1 537 ? 232.799 231.775 196.906 1.00 43.86  ? 537 PHE B N   1 
ATOM   10331 C  CA  . PHE B 1 537 ? 233.823 231.119 196.117 1.00 48.36  ? 537 PHE B CA  1 
ATOM   10332 C  C   . PHE B 1 537 ? 235.125 231.047 196.905 1.00 52.59  ? 537 PHE B C   1 
ATOM   10333 O  O   . PHE B 1 537 ? 235.215 231.495 198.048 1.00 57.77  ? 537 PHE B O   1 
ATOM   10334 C  CB  . PHE B 1 537 ? 234.059 231.862 194.809 1.00 54.64  ? 537 PHE B CB  1 
ATOM   10335 C  CG  . PHE B 1 537 ? 232.889 231.841 193.879 1.00 57.71  ? 537 PHE B CG  1 
ATOM   10336 C  CD1 . PHE B 1 537 ? 232.686 230.784 193.025 1.00 55.93  ? 537 PHE B CD1 1 
ATOM   10337 C  CD2 . PHE B 1 537 ? 232.002 232.896 193.845 1.00 63.51  ? 537 PHE B CD2 1 
ATOM   10338 C  CE1 . PHE B 1 537 ? 231.616 230.773 192.164 1.00 58.90  ? 537 PHE B CE1 1 
ATOM   10339 C  CE2 . PHE B 1 537 ? 230.931 232.887 192.986 1.00 61.30  ? 537 PHE B CE2 1 
ATOM   10340 C  CZ  . PHE B 1 537 ? 230.739 231.823 192.146 1.00 62.28  ? 537 PHE B CZ  1 
ATOM   10341 N  N   . PHE B 1 538 ? 236.155 230.488 196.279 1.00 54.74  ? 538 PHE B N   1 
ATOM   10342 C  CA  . PHE B 1 538 ? 237.476 230.523 196.887 1.00 66.53  ? 538 PHE B CA  1 
ATOM   10343 C  C   . PHE B 1 538 ? 238.391 231.547 196.232 1.00 73.43  ? 538 PHE B C   1 
ATOM   10344 O  O   . PHE B 1 538 ? 239.032 232.336 196.930 1.00 75.95  ? 538 PHE B O   1 
ATOM   10345 C  CB  . PHE B 1 538 ? 238.142 229.148 196.834 1.00 74.22  ? 538 PHE B CB  1 
ATOM   10346 C  CG  . PHE B 1 538 ? 239.469 229.103 197.535 1.00 83.01  ? 538 PHE B CG  1 
ATOM   10347 C  CD1 . PHE B 1 538 ? 239.535 229.085 198.916 1.00 83.86  ? 538 PHE B CD1 1 
ATOM   10348 C  CD2 . PHE B 1 538 ? 240.648 229.106 196.812 1.00 85.01  ? 538 PHE B CD2 1 
ATOM   10349 C  CE1 . PHE B 1 538 ? 240.749 229.055 199.562 1.00 83.46  ? 538 PHE B CE1 1 
ATOM   10350 C  CE2 . PHE B 1 538 ? 241.866 229.076 197.453 1.00 87.24  ? 538 PHE B CE2 1 
ATOM   10351 C  CZ  . PHE B 1 538 ? 241.917 229.050 198.831 1.00 87.13  ? 538 PHE B CZ  1 
ATOM   10352 N  N   . SER B 1 539 ? 238.471 231.545 194.906 1.00 76.62  ? 539 SER B N   1 
ATOM   10353 C  CA  . SER B 1 539 ? 239.335 232.491 194.220 1.00 86.54  ? 539 SER B CA  1 
ATOM   10354 C  C   . SER B 1 539 ? 238.828 233.912 194.449 1.00 87.65  ? 539 SER B C   1 
ATOM   10355 O  O   . SER B 1 539 ? 237.632 234.177 194.295 1.00 89.58  ? 539 SER B O   1 
ATOM   10356 C  CB  . SER B 1 539 ? 239.392 232.185 192.726 1.00 86.92  ? 539 SER B CB  1 
ATOM   10357 O  OG  . SER B 1 539 ? 240.260 233.081 192.057 1.00 87.80  ? 539 SER B OG  1 
ATOM   10358 N  N   . PRO B 1 540 ? 239.702 234.839 194.815 1.00 83.82  ? 540 PRO B N   1 
ATOM   10359 C  CA  . PRO B 1 540 ? 239.232 236.152 195.272 1.00 84.33  ? 540 PRO B CA  1 
ATOM   10360 C  C   . PRO B 1 540 ? 238.776 237.062 194.141 1.00 88.56  ? 540 PRO B C   1 
ATOM   10361 O  O   . PRO B 1 540 ? 237.783 237.787 194.277 1.00 88.41  ? 540 PRO B O   1 
ATOM   10362 C  CB  . PRO B 1 540 ? 240.462 236.723 195.983 1.00 83.79  ? 540 PRO B CB  1 
ATOM   10363 C  CG  . PRO B 1 540 ? 241.615 236.095 195.275 1.00 82.55  ? 540 PRO B CG  1 
ATOM   10364 C  CD  . PRO B 1 540 ? 241.171 234.742 194.800 1.00 82.10  ? 540 PRO B CD  1 
ATOM   10365 N  N   . ALA B 1 541 ? 239.493 237.025 193.017 1.00 88.20  ? 541 ALA B N   1 
ATOM   10366 C  CA  . ALA B 1 541 ? 239.202 237.946 191.925 1.00 86.83  ? 541 ALA B CA  1 
ATOM   10367 C  C   . ALA B 1 541 ? 237.781 237.757 191.415 1.00 86.07  ? 541 ALA B C   1 
ATOM   10368 O  O   . ALA B 1 541 ? 237.031 238.724 191.240 1.00 85.94  ? 541 ALA B O   1 
ATOM   10369 C  CB  . ALA B 1 541 ? 240.213 237.754 190.796 1.00 85.20  ? 541 ALA B CB  1 
ATOM   10370 N  N   . MET B 1 542 ? 237.380 236.515 191.185 1.00 84.26  ? 542 MET B N   1 
ATOM   10371 C  CA  . MET B 1 542 ? 236.042 236.298 190.663 1.00 85.58  ? 542 MET B CA  1 
ATOM   10372 C  C   . MET B 1 542 ? 234.996 236.272 191.772 1.00 82.56  ? 542 MET B C   1 
ATOM   10373 O  O   . MET B 1 542 ? 233.807 236.498 191.499 1.00 85.98  ? 542 MET B O   1 
ATOM   10374 C  CB  . MET B 1 542 ? 236.054 235.043 189.784 1.00 90.49  ? 542 MET B CB  1 
ATOM   10375 C  CG  . MET B 1 542 ? 236.426 233.739 190.441 1.00 92.58  ? 542 MET B CG  1 
ATOM   10376 S  SD  . MET B 1 542 ? 235.712 232.400 189.467 1.00 112.85 ? 542 MET B SD  1 
ATOM   10377 C  CE  . MET B 1 542 ? 234.299 231.963 190.446 1.00 82.53  ? 542 MET B CE  1 
ATOM   10378 N  N   . ASN B 1 543 ? 235.424 236.105 193.024 1.00 74.21  ? 543 ASN B N   1 
ATOM   10379 C  CA  . ASN B 1 543 ? 234.552 236.422 194.147 1.00 74.14  ? 543 ASN B CA  1 
ATOM   10380 C  C   . ASN B 1 543 ? 234.284 237.920 194.267 1.00 82.95  ? 543 ASN B C   1 
ATOM   10381 O  O   . ASN B 1 543 ? 233.355 238.313 194.979 1.00 84.82  ? 543 ASN B O   1 
ATOM   10382 C  CB  . ASN B 1 543 ? 235.150 235.898 195.449 1.00 73.05  ? 543 ASN B CB  1 
ATOM   10383 C  CG  . ASN B 1 543 ? 234.168 235.944 196.594 1.00 70.51  ? 543 ASN B CG  1 
ATOM   10384 O  OD1 . ASN B 1 543 ? 233.182 235.212 196.612 1.00 69.35  ? 543 ASN B OD1 1 
ATOM   10385 N  ND2 . ASN B 1 543 ? 234.426 236.818 197.556 1.00 70.12  ? 543 ASN B ND2 1 
ATOM   10386 N  N   . GLU B 1 544 ? 235.091 238.764 193.619 1.00 85.18  ? 544 GLU B N   1 
ATOM   10387 C  CA  . GLU B 1 544 ? 234.751 240.174 193.431 1.00 82.43  ? 544 GLU B CA  1 
ATOM   10388 C  C   . GLU B 1 544 ? 234.027 240.433 192.121 1.00 78.96  ? 544 GLU B C   1 
ATOM   10389 O  O   . GLU B 1 544 ? 233.278 241.411 192.008 1.00 79.27  ? 544 GLU B O   1 
ATOM   10390 C  CB  . GLU B 1 544 ? 236.010 241.046 193.479 1.00 85.96  ? 544 GLU B CB  1 
ATOM   10391 C  CG  . GLU B 1 544 ? 236.671 241.123 194.844 1.00 94.28  ? 544 GLU B CG  1 
ATOM   10392 C  CD  . GLU B 1 544 ? 235.990 242.123 195.759 1.00 98.56  ? 544 GLU B CD  1 
ATOM   10393 O  OE1 . GLU B 1 544 ? 236.042 243.335 195.459 1.00 102.12 ? 544 GLU B OE1 1 
ATOM   10394 O  OE2 . GLU B 1 544 ? 235.401 241.699 196.775 1.00 97.86  ? 544 GLU B OE2 1 
ATOM   10395 N  N   . MET B 1 545 ? 234.260 239.580 191.129 1.00 77.25  ? 545 MET B N   1 
ATOM   10396 C  CA  . MET B 1 545 ? 233.514 239.662 189.879 1.00 73.34  ? 545 MET B CA  1 
ATOM   10397 C  C   . MET B 1 545 ? 232.023 239.456 190.112 1.00 71.29  ? 545 MET B C   1 
ATOM   10398 O  O   . MET B 1 545 ? 231.188 240.137 189.499 1.00 75.70  ? 545 MET B O   1 
ATOM   10399 C  CB  . MET B 1 545 ? 234.060 238.634 188.894 1.00 71.46  ? 545 MET B CB  1 
ATOM   10400 C  CG  . MET B 1 545 ? 233.393 238.627 187.547 1.00 76.70  ? 545 MET B CG  1 
ATOM   10401 S  SD  . MET B 1 545 ? 232.108 237.380 187.539 1.00 86.73  ? 545 MET B SD  1 
ATOM   10402 C  CE  . MET B 1 545 ? 232.988 236.086 188.404 1.00 79.10  ? 545 MET B CE  1 
ATOM   10403 N  N   . VAL B 1 546 ? 231.665 238.522 190.991 1.00 67.36  ? 546 VAL B N   1 
ATOM   10404 C  CA  . VAL B 1 546 ? 230.251 238.360 191.325 1.00 66.29  ? 546 VAL B CA  1 
ATOM   10405 C  C   . VAL B 1 546 ? 229.698 239.642 191.942 1.00 70.44  ? 546 VAL B C   1 
ATOM   10406 O  O   . VAL B 1 546 ? 228.560 240.046 191.663 1.00 73.21  ? 546 VAL B O   1 
ATOM   10407 C  CB  . VAL B 1 546 ? 230.041 237.142 192.242 1.00 66.84  ? 546 VAL B CB  1 
ATOM   10408 C  CG1 . VAL B 1 546 ? 230.914 237.231 193.462 1.00 72.06  ? 546 VAL B CG1 1 
ATOM   10409 C  CG2 . VAL B 1 546 ? 228.589 237.035 192.645 1.00 59.57  ? 546 VAL B CG2 1 
ATOM   10410 N  N   . LYS B 1 547 ? 230.503 240.321 192.761 1.00 72.18  ? 547 LYS B N   1 
ATOM   10411 C  CA  . LYS B 1 547 ? 230.063 241.579 193.355 1.00 71.88  ? 547 LYS B CA  1 
ATOM   10412 C  C   . LYS B 1 547 ? 229.844 242.650 192.295 1.00 69.61  ? 547 LYS B C   1 
ATOM   10413 O  O   . LYS B 1 547 ? 228.881 243.423 192.368 1.00 70.90  ? 547 LYS B O   1 
ATOM   10414 C  CB  . LYS B 1 547 ? 231.083 242.053 194.388 1.00 75.97  ? 547 LYS B CB  1 
ATOM   10415 C  CG  . LYS B 1 547 ? 230.482 242.835 195.541 1.00 82.10  ? 547 LYS B CG  1 
ATOM   10416 C  CD  . LYS B 1 547 ? 231.403 242.824 196.750 1.00 84.34  ? 547 LYS B CD  1 
ATOM   10417 C  CE  . LYS B 1 547 ? 230.945 241.808 197.785 1.00 84.58  ? 547 LYS B CE  1 
ATOM   10418 N  NZ  . LYS B 1 547 ? 229.724 242.262 198.507 1.00 91.56  ? 547 LYS B NZ  1 
ATOM   10419 N  N   . GLU B 1 548 ? 230.738 242.725 191.309 1.00 66.45  ? 548 GLU B N   1 
ATOM   10420 C  CA  . GLU B 1 548 ? 230.573 243.733 190.265 1.00 63.30  ? 548 GLU B CA  1 
ATOM   10421 C  C   . GLU B 1 548 ? 229.328 243.446 189.436 1.00 62.74  ? 548 GLU B C   1 
ATOM   10422 O  O   . GLU B 1 548 ? 228.627 244.374 189.013 1.00 65.58  ? 548 GLU B O   1 
ATOM   10423 C  CB  . GLU B 1 548 ? 231.848 243.813 189.411 1.00 66.34  ? 548 GLU B CB  1 
ATOM   10424 C  CG  . GLU B 1 548 ? 232.022 242.854 188.221 1.00 73.96  ? 548 GLU B CG  1 
ATOM   10425 C  CD  . GLU B 1 548 ? 231.107 243.134 187.033 1.00 81.55  ? 548 GLU B CD  1 
ATOM   10426 O  OE1 . GLU B 1 548 ? 230.530 244.239 186.957 1.00 83.29  ? 548 GLU B OE1 1 
ATOM   10427 O  OE2 . GLU B 1 548 ? 230.967 242.240 186.172 1.00 79.75  ? 548 GLU B OE2 1 
ATOM   10428 N  N   . ARG B 1 549 ? 229.025 242.168 189.208 1.00 62.10  ? 549 ARG B N   1 
ATOM   10429 C  CA  . ARG B 1 549 ? 227.778 241.829 188.530 1.00 61.59  ? 549 ARG B CA  1 
ATOM   10430 C  C   . ARG B 1 549 ? 226.577 242.251 189.359 1.00 60.14  ? 549 ARG B C   1 
ATOM   10431 O  O   . ARG B 1 549 ? 225.567 242.714 188.816 1.00 66.93  ? 549 ARG B O   1 
ATOM   10432 C  CB  . ARG B 1 549 ? 227.715 240.335 188.227 1.00 62.59  ? 549 ARG B CB  1 
ATOM   10433 C  CG  . ARG B 1 549 ? 226.511 239.933 187.393 1.00 58.37  ? 549 ARG B CG  1 
ATOM   10434 C  CD  . ARG B 1 549 ? 226.747 238.627 186.668 1.00 56.00  ? 549 ARG B CD  1 
ATOM   10435 N  NE  . ARG B 1 549 ? 226.417 238.723 185.253 1.00 57.76  ? 549 ARG B NE  1 
ATOM   10436 C  CZ  . ARG B 1 549 ? 225.501 237.983 184.647 1.00 61.90  ? 549 ARG B CZ  1 
ATOM   10437 N  NH1 . ARG B 1 549 ? 224.802 237.074 185.303 1.00 66.05  ? 549 ARG B NH1 1 
ATOM   10438 N  NH2 . ARG B 1 549 ? 225.284 238.155 183.348 1.00 61.03  ? 549 ARG B NH2 1 
ATOM   10439 N  N   . LEU B 1 550 ? 226.662 242.093 190.677 1.00 58.04  ? 550 LEU B N   1 
ATOM   10440 C  CA  . LEU B 1 550 ? 225.574 242.554 191.532 1.00 60.79  ? 550 LEU B CA  1 
ATOM   10441 C  C   . LEU B 1 550 ? 225.408 244.066 191.443 1.00 67.52  ? 550 LEU B C   1 
ATOM   10442 O  O   . LEU B 1 550 ? 224.286 244.582 191.484 1.00 71.00  ? 550 LEU B O   1 
ATOM   10443 C  CB  . LEU B 1 550 ? 225.820 242.125 192.974 1.00 63.71  ? 550 LEU B CB  1 
ATOM   10444 C  CG  . LEU B 1 550 ? 224.681 242.423 193.943 1.00 67.17  ? 550 LEU B CG  1 
ATOM   10445 C  CD1 . LEU B 1 550 ? 223.397 241.782 193.452 1.00 63.52  ? 550 LEU B CD1 1 
ATOM   10446 C  CD2 . LEU B 1 550 ? 225.030 241.930 195.335 1.00 68.98  ? 550 LEU B CD2 1 
ATOM   10447 N  N   . VAL B 1 551 ? 226.520 244.794 191.327 1.00 68.01  ? 551 VAL B N   1 
ATOM   10448 C  CA  . VAL B 1 551 ? 226.451 246.245 191.150 1.00 66.26  ? 551 VAL B CA  1 
ATOM   10449 C  C   . VAL B 1 551 ? 225.754 246.593 189.841 1.00 64.10  ? 551 VAL B C   1 
ATOM   10450 O  O   . VAL B 1 551 ? 224.910 247.497 189.785 1.00 66.13  ? 551 VAL B O   1 
ATOM   10451 C  CB  . VAL B 1 551 ? 227.861 246.855 191.214 1.00 66.63  ? 551 VAL B CB  1 
ATOM   10452 C  CG1 . VAL B 1 551 ? 227.905 248.169 190.458 1.00 63.77  ? 551 VAL B CG1 1 
ATOM   10453 C  CG2 . VAL B 1 551 ? 228.288 247.048 192.662 1.00 65.68  ? 551 VAL B CG2 1 
ATOM   10454 N  N   . LEU B 1 552 ? 226.112 245.894 188.765 1.00 63.24  ? 552 LEU B N   1 
ATOM   10455 C  CA  . LEU B 1 552 ? 225.440 246.116 187.489 1.00 61.53  ? 552 LEU B CA  1 
ATOM   10456 C  C   . LEU B 1 552 ? 223.950 245.854 187.615 1.00 58.01  ? 552 LEU B C   1 
ATOM   10457 O  O   . LEU B 1 552 ? 223.128 246.600 187.073 1.00 60.95  ? 552 LEU B O   1 
ATOM   10458 C  CB  . LEU B 1 552 ? 226.048 245.220 186.411 1.00 64.62  ? 552 LEU B CB  1 
ATOM   10459 C  CG  . LEU B 1 552 ? 225.772 245.602 184.961 1.00 66.88  ? 552 LEU B CG  1 
ATOM   10460 C  CD1 . LEU B 1 552 ? 226.240 247.014 184.704 1.00 67.18  ? 552 LEU B CD1 1 
ATOM   10461 C  CD2 . LEU B 1 552 ? 226.462 244.648 184.019 1.00 65.25  ? 552 LEU B CD2 1 
ATOM   10462 N  N   . GLY B 1 553 ? 223.586 244.794 188.325 1.00 58.96  ? 553 GLY B N   1 
ATOM   10463 C  CA  . GLY B 1 553 ? 222.183 244.515 188.537 1.00 63.04  ? 553 GLY B CA  1 
ATOM   10464 C  C   . GLY B 1 553 ? 221.489 245.607 189.320 1.00 67.74  ? 553 GLY B C   1 
ATOM   10465 O  O   . GLY B 1 553 ? 220.332 245.935 189.054 1.00 77.00  ? 553 GLY B O   1 
ATOM   10466 N  N   . ALA B 1 554 ? 222.179 246.176 190.308 1.00 66.73  ? 554 ALA B N   1 
ATOM   10467 C  CA  . ALA B 1 554 ? 221.593 247.279 191.063 1.00 72.58  ? 554 ALA B CA  1 
ATOM   10468 C  C   . ALA B 1 554 ? 221.350 248.484 190.164 1.00 76.63  ? 554 ALA B C   1 
ATOM   10469 O  O   . ALA B 1 554 ? 220.290 249.120 190.229 1.00 78.05  ? 554 ALA B O   1 
ATOM   10470 C  CB  . ALA B 1 554 ? 222.498 247.654 192.235 1.00 68.16  ? 554 ALA B CB  1 
ATOM   10471 N  N   . ALA B 1 555 ? 222.319 248.798 189.305 1.00 76.29  ? 555 ALA B N   1 
ATOM   10472 C  CA  . ALA B 1 555 ? 222.147 249.904 188.371 1.00 71.71  ? 555 ALA B CA  1 
ATOM   10473 C  C   . ALA B 1 555 ? 220.987 249.641 187.423 1.00 67.46  ? 555 ALA B C   1 
ATOM   10474 O  O   . ALA B 1 555 ? 220.210 250.549 187.113 1.00 69.53  ? 555 ALA B O   1 
ATOM   10475 C  CB  . ALA B 1 555 ? 223.437 250.142 187.591 1.00 68.29  ? 555 ALA B CB  1 
ATOM   10476 N  N   . LEU B 1 556 ? 220.858 248.405 186.946 1.00 65.34  ? 556 LEU B N   1 
ATOM   10477 C  CA  . LEU B 1 556 ? 219.754 248.066 186.058 1.00 65.24  ? 556 LEU B CA  1 
ATOM   10478 C  C   . LEU B 1 556 ? 218.415 248.182 186.767 1.00 69.38  ? 556 LEU B C   1 
ATOM   10479 O  O   . LEU B 1 556 ? 217.428 248.621 186.168 1.00 74.72  ? 556 LEU B O   1 
ATOM   10480 C  CB  . LEU B 1 556 ? 219.940 246.659 185.506 1.00 68.90  ? 556 LEU B CB  1 
ATOM   10481 C  CG  . LEU B 1 556 ? 218.978 246.159 184.431 1.00 72.22  ? 556 LEU B CG  1 
ATOM   10482 C  CD1 . LEU B 1 556 ? 219.700 245.118 183.624 1.00 69.59  ? 556 LEU B CD1 1 
ATOM   10483 C  CD2 . LEU B 1 556 ? 217.706 245.568 185.013 1.00 77.63  ? 556 LEU B CD2 1 
ATOM   10484 N  N   . LYS B 1 557 ? 218.342 247.748 188.025 1.00 68.98  ? 557 LYS B N   1 
ATOM   10485 C  CA  . LYS B 1 557 ? 217.097 247.900 188.767 1.00 72.24  ? 557 LYS B CA  1 
ATOM   10486 C  C   . LYS B 1 557 ? 216.749 249.367 188.927 1.00 76.93  ? 557 LYS B C   1 
ATOM   10487 O  O   . LYS B 1 557 ? 215.583 249.760 188.787 1.00 82.72  ? 557 LYS B O   1 
ATOM   10488 C  CB  . LYS B 1 557 ? 217.194 247.230 190.130 1.00 74.19  ? 557 LYS B CB  1 
ATOM   10489 C  CG  . LYS B 1 557 ? 215.854 246.736 190.650 1.00 77.82  ? 557 LYS B CG  1 
ATOM   10490 C  CD  . LYS B 1 557 ? 215.878 246.369 192.134 1.00 83.71  ? 557 LYS B CD  1 
ATOM   10491 C  CE  . LYS B 1 557 ? 217.251 245.948 192.661 1.00 87.08  ? 557 LYS B CE  1 
ATOM   10492 N  NZ  . LYS B 1 557 ? 217.908 244.848 191.889 1.00 88.84  ? 557 LYS B NZ  1 
ATOM   10493 N  N   . GLU B 1 558 ? 217.754 250.198 189.201 1.00 75.83  ? 558 GLU B N   1 
ATOM   10494 C  CA  . GLU B 1 558 ? 217.511 251.633 189.274 1.00 77.55  ? 558 GLU B CA  1 
ATOM   10495 C  C   . GLU B 1 558 ? 216.999 252.164 187.943 1.00 74.50  ? 558 GLU B C   1 
ATOM   10496 O  O   . GLU B 1 558 ? 216.049 252.954 187.905 1.00 76.09  ? 558 GLU B O   1 
ATOM   10497 C  CB  . GLU B 1 558 ? 218.792 252.354 189.691 1.00 80.85  ? 558 GLU B CB  1 
ATOM   10498 C  CG  . GLU B 1 558 ? 218.922 253.767 189.155 1.00 81.44  ? 558 GLU B CG  1 
ATOM   10499 C  CD  . GLU B 1 558 ? 218.125 254.769 189.965 1.00 84.72  ? 558 GLU B CD  1 
ATOM   10500 O  OE1 . GLU B 1 558 ? 217.936 254.537 191.178 1.00 88.06  ? 558 GLU B OE1 1 
ATOM   10501 O  OE2 . GLU B 1 558 ? 217.689 255.788 189.390 1.00 81.83  ? 558 GLU B OE2 1 
ATOM   10502 N  N   . ALA B 1 559 ? 217.602 251.723 186.841 1.00 73.96  ? 559 ALA B N   1 
ATOM   10503 C  CA  . ALA B 1 559 ? 217.218 252.225 185.527 1.00 75.79  ? 559 ALA B CA  1 
ATOM   10504 C  C   . ALA B 1 559 ? 215.792 251.829 185.172 1.00 73.74  ? 559 ALA B C   1 
ATOM   10505 O  O   . ALA B 1 559 ? 215.016 252.655 184.679 1.00 74.99  ? 559 ALA B O   1 
ATOM   10506 C  CB  . ALA B 1 559 ? 218.194 251.716 184.468 1.00 76.31  ? 559 ALA B CB  1 
ATOM   10507 N  N   . ILE B 1 560 ? 215.424 250.572 185.415 1.00 71.49  ? 560 ILE B N   1 
ATOM   10508 C  CA  . ILE B 1 560 ? 214.063 250.151 185.104 1.00 73.73  ? 560 ILE B CA  1 
ATOM   10509 C  C   . ILE B 1 560 ? 213.077 250.832 186.036 1.00 74.54  ? 560 ILE B C   1 
ATOM   10510 O  O   . ILE B 1 560 ? 211.921 251.062 185.665 1.00 77.72  ? 560 ILE B O   1 
ATOM   10511 C  CB  . ILE B 1 560 ? 213.926 248.616 185.159 1.00 80.90  ? 560 ILE B CB  1 
ATOM   10512 C  CG1 . ILE B 1 560 ? 214.071 248.099 186.592 1.00 80.55  ? 560 ILE B CG1 1 
ATOM   10513 C  CG2 . ILE B 1 560 ? 214.947 247.949 184.252 1.00 78.83  ? 560 ILE B CG2 1 
ATOM   10514 C  CD1 . ILE B 1 560 ? 214.043 246.590 186.705 1.00 78.10  ? 560 ILE B CD1 1 
ATOM   10515 N  N   . SER B 1 561 ? 213.506 251.166 187.254 1.00 75.41  ? 561 SER B N   1 
ATOM   10516 C  CA  . SER B 1 561 ? 212.598 251.797 188.203 1.00 79.77  ? 561 SER B CA  1 
ATOM   10517 C  C   . SER B 1 561 ? 212.205 253.200 187.754 1.00 79.58  ? 561 SER B C   1 
ATOM   10518 O  O   . SER B 1 561 ? 211.033 253.581 187.851 1.00 80.49  ? 561 SER B O   1 
ATOM   10519 C  CB  . SER B 1 561 ? 213.236 251.834 189.590 1.00 79.54  ? 561 SER B CB  1 
ATOM   10520 O  OG  . SER B 1 561 ? 213.647 250.538 189.990 1.00 81.40  ? 561 SER B OG  1 
ATOM   10521 N  N   . ASN B 1 562 ? 213.163 253.982 187.258 1.00 76.69  ? 562 ASN B N   1 
ATOM   10522 C  CA  . ASN B 1 562 ? 212.911 255.366 186.886 1.00 71.83  ? 562 ASN B CA  1 
ATOM   10523 C  C   . ASN B 1 562 ? 212.816 255.557 185.380 1.00 69.15  ? 562 ASN B C   1 
ATOM   10524 O  O   . ASN B 1 562 ? 213.099 256.650 184.885 1.00 71.31  ? 562 ASN B O   1 
ATOM   10525 C  CB  . ASN B 1 562 ? 213.982 256.281 187.479 1.00 70.11  ? 562 ASN B CB  1 
ATOM   10526 C  CG  . ASN B 1 562 ? 215.350 256.033 186.901 1.00 71.50  ? 562 ASN B CG  1 
ATOM   10527 O  OD1 . ASN B 1 562 ? 215.560 255.085 186.149 1.00 74.59  ? 562 ASN B OD1 1 
ATOM   10528 N  ND2 . ASN B 1 562 ? 216.299 256.887 187.256 1.00 69.74  ? 562 ASN B ND2 1 
ATOM   10529 N  N   . ASN B 1 563 ? 212.427 254.515 184.653 1.00 69.36  ? 563 ASN B N   1 
ATOM   10530 C  CA  . ASN B 1 563 ? 212.110 254.565 183.222 1.00 74.60  ? 563 ASN B CA  1 
ATOM   10531 C  C   . ASN B 1 563 ? 213.108 255.415 182.429 1.00 76.95  ? 563 ASN B C   1 
ATOM   10532 O  O   . ASN B 1 563 ? 212.779 256.452 181.854 1.00 79.11  ? 563 ASN B O   1 
ATOM   10533 C  CB  . ASN B 1 563 ? 210.671 255.035 183.001 1.00 74.49  ? 563 ASN B CB  1 
ATOM   10534 C  CG  . ASN B 1 563 ? 210.304 256.227 183.848 1.00 77.18  ? 563 ASN B CG  1 
ATOM   10535 O  OD1 . ASN B 1 563 ? 210.614 257.367 183.508 1.00 78.76  ? 563 ASN B OD1 1 
ATOM   10536 N  ND2 . ASN B 1 563 ? 209.661 255.968 184.977 1.00 74.40  ? 563 ASN B ND2 1 
ATOM   10537 N  N   . GLN B 1 564 ? 214.355 254.943 182.414 1.00 73.02  ? 564 GLN B N   1 
ATOM   10538 C  CA  . GLN B 1 564 ? 215.415 255.540 181.612 1.00 65.24  ? 564 GLN B CA  1 
ATOM   10539 C  C   . GLN B 1 564 ? 215.681 254.770 180.324 1.00 65.74  ? 564 GLN B C   1 
ATOM   10540 O  O   . GLN B 1 564 ? 216.111 255.379 179.340 1.00 65.45  ? 564 GLN B O   1 
ATOM   10541 C  CB  . GLN B 1 564 ? 216.679 255.671 182.487 1.00 66.16  ? 564 GLN B CB  1 
ATOM   10542 C  CG  . GLN B 1 564 ? 217.965 256.337 181.937 1.00 70.66  ? 564 GLN B CG  1 
ATOM   10543 C  CD  . GLN B 1 564 ? 218.562 255.728 180.677 1.00 75.09  ? 564 GLN B CD  1 
ATOM   10544 O  OE1 . GLN B 1 564 ? 218.449 254.528 180.433 1.00 71.45  ? 564 GLN B OE1 1 
ATOM   10545 N  NE2 . GLN B 1 564 ? 219.201 256.564 179.868 1.00 78.10  ? 564 GLN B NE2 1 
ATOM   10546 N  N   . LEU B 1 565 ? 215.389 253.470 180.291 1.00 66.65  ? 565 LEU B N   1 
ATOM   10547 C  CA  . LEU B 1 565 ? 215.602 252.651 179.104 1.00 61.21  ? 565 LEU B CA  1 
ATOM   10548 C  C   . LEU B 1 565 ? 214.905 253.251 177.886 1.00 58.85  ? 565 LEU B C   1 
ATOM   10549 O  O   . LEU B 1 565 ? 213.964 254.034 177.997 1.00 63.65  ? 565 LEU B O   1 
ATOM   10550 C  CB  . LEU B 1 565 ? 215.068 251.240 179.328 1.00 59.38  ? 565 LEU B CB  1 
ATOM   10551 C  CG  . LEU B 1 565 ? 215.764 250.327 180.326 1.00 57.62  ? 565 LEU B CG  1 
ATOM   10552 C  CD1 . LEU B 1 565 ? 214.722 249.589 181.135 1.00 61.08  ? 565 LEU B CD1 1 
ATOM   10553 C  CD2 . LEU B 1 565 ? 216.637 249.353 179.589 1.00 55.06  ? 565 LEU B CD2 1 
ATOM   10554 N  N   . LYS B 1 566 ? 215.373 252.864 176.705 1.00 52.80  ? 566 LYS B N   1 
ATOM   10555 C  CA  . LYS B 1 566 ? 214.808 253.363 175.463 1.00 51.00  ? 566 LYS B CA  1 
ATOM   10556 C  C   . LYS B 1 566 ? 214.388 252.199 174.583 1.00 56.54  ? 566 LYS B C   1 
ATOM   10557 O  O   . LYS B 1 566 ? 214.787 251.052 174.797 1.00 60.19  ? 566 LYS B O   1 
ATOM   10558 C  CB  . LYS B 1 566 ? 215.799 254.247 174.705 1.00 46.60  ? 566 LYS B CB  1 
ATOM   10559 C  CG  . LYS B 1 566 ? 216.342 255.392 175.519 1.00 53.87  ? 566 LYS B CG  1 
ATOM   10560 C  CD  . LYS B 1 566 ? 215.266 256.407 175.814 1.00 56.60  ? 566 LYS B CD  1 
ATOM   10561 C  CE  . LYS B 1 566 ? 215.839 257.618 176.521 1.00 60.49  ? 566 LYS B CE  1 
ATOM   10562 N  NZ  . LYS B 1 566 ? 214.806 258.661 176.765 1.00 66.47  ? 566 LYS B NZ  1 
ATOM   10563 N  N   . LEU B 1 567 ? 213.573 252.510 173.580 1.00 55.12  ? 567 LEU B N   1 
ATOM   10564 C  CA  . LEU B 1 567 ? 213.100 251.527 172.615 1.00 46.69  ? 567 LEU B CA  1 
ATOM   10565 C  C   . LEU B 1 567 ? 213.484 251.997 171.221 1.00 49.03  ? 567 LEU B C   1 
ATOM   10566 O  O   . LEU B 1 567 ? 212.860 252.913 170.678 1.00 57.10  ? 567 LEU B O   1 
ATOM   10567 C  CB  . LEU B 1 567 ? 211.594 251.339 172.736 1.00 48.08  ? 567 LEU B CB  1 
ATOM   10568 C  CG  . LEU B 1 567 ? 211.135 250.786 174.079 1.00 57.90  ? 567 LEU B CG  1 
ATOM   10569 C  CD1 . LEU B 1 567 ? 209.619 250.696 174.132 1.00 69.44  ? 567 LEU B CD1 1 
ATOM   10570 C  CD2 . LEU B 1 567 ? 211.766 249.432 174.329 1.00 57.53  ? 567 LEU B CD2 1 
ATOM   10571 N  N   . VAL B 1 568 ? 214.485 251.379 170.647 1.00 44.66  ? 568 VAL B N   1 
ATOM   10572 C  CA  . VAL B 1 568 ? 214.935 251.707 169.303 1.00 45.42  ? 568 VAL B CA  1 
ATOM   10573 C  C   . VAL B 1 568 ? 214.106 250.906 168.311 1.00 50.47  ? 568 VAL B C   1 
ATOM   10574 O  O   . VAL B 1 568 ? 213.834 249.719 168.527 1.00 54.30  ? 568 VAL B O   1 
ATOM   10575 C  CB  . VAL B 1 568 ? 216.434 251.416 169.148 1.00 43.03  ? 568 VAL B CB  1 
ATOM   10576 C  CG1 . VAL B 1 568 ? 216.822 251.376 167.692 1.00 50.55  ? 568 VAL B CG1 1 
ATOM   10577 C  CG2 . VAL B 1 568 ? 217.243 252.460 169.879 1.00 45.23  ? 568 VAL B CG2 1 
ATOM   10578 N  N   . TYR B 1 569 ? 213.678 251.555 167.230 1.00 48.68  ? 569 TYR B N   1 
ATOM   10579 C  CA  . TYR B 1 569 ? 212.766 250.956 166.268 1.00 46.82  ? 569 TYR B CA  1 
ATOM   10580 C  C   . TYR B 1 569 ? 213.464 250.715 164.937 1.00 50.97  ? 569 TYR B C   1 
ATOM   10581 O  O   . TYR B 1 569 ? 214.121 251.614 164.406 1.00 57.01  ? 569 TYR B O   1 
ATOM   10582 C  CB  . TYR B 1 569 ? 211.549 251.842 166.075 1.00 43.74  ? 569 TYR B CB  1 
ATOM   10583 C  CG  . TYR B 1 569 ? 210.827 252.152 167.355 1.00 47.16  ? 569 TYR B CG  1 
ATOM   10584 C  CD1 . TYR B 1 569 ? 209.969 251.236 167.930 1.00 49.53  ? 569 TYR B CD1 1 
ATOM   10585 C  CD2 . TYR B 1 569 ? 210.996 253.365 167.986 1.00 53.34  ? 569 TYR B CD2 1 
ATOM   10586 C  CE1 . TYR B 1 569 ? 209.299 251.523 169.099 1.00 49.95  ? 569 TYR B CE1 1 
ATOM   10587 C  CE2 . TYR B 1 569 ? 210.333 253.656 169.151 1.00 57.24  ? 569 TYR B CE2 1 
ATOM   10588 C  CZ  . TYR B 1 569 ? 209.488 252.730 169.703 1.00 54.61  ? 569 TYR B CZ  1 
ATOM   10589 O  OH  . TYR B 1 569 ? 208.830 253.020 170.869 1.00 59.24  ? 569 TYR B OH  1 
ATOM   10590 N  N   . GLN B 1 570 ? 213.309 249.505 164.401 1.00 51.32  ? 570 GLN B N   1 
ATOM   10591 C  CA  . GLN B 1 570 ? 213.934 249.094 163.141 1.00 50.96  ? 570 GLN B CA  1 
ATOM   10592 C  C   . GLN B 1 570 ? 212.873 248.730 162.116 1.00 52.90  ? 570 GLN B C   1 
ATOM   10593 O  O   . GLN B 1 570 ? 212.018 247.878 162.403 1.00 58.73  ? 570 GLN B O   1 
ATOM   10594 C  CB  . GLN B 1 570 ? 214.860 247.905 163.345 1.00 50.99  ? 570 GLN B CB  1 
ATOM   10595 C  CG  . GLN B 1 570 ? 215.017 247.091 162.084 1.00 53.18  ? 570 GLN B CG  1 
ATOM   10596 C  CD  . GLN B 1 570 ? 216.266 246.257 162.072 1.00 60.56  ? 570 GLN B CD  1 
ATOM   10597 O  OE1 . GLN B 1 570 ? 216.961 246.179 161.063 1.00 66.11  ? 570 GLN B OE1 1 
ATOM   10598 N  NE2 . GLN B 1 570 ? 216.559 245.617 163.192 1.00 58.37  ? 570 GLN B NE2 1 
ATOM   10599 N  N   . PRO B 1 571 ? 212.888 249.305 160.918 1.00 51.11  ? 571 PRO B N   1 
ATOM   10600 C  CA  . PRO B 1 571 ? 211.797 249.057 159.972 1.00 54.99  ? 571 PRO B CA  1 
ATOM   10601 C  C   . PRO B 1 571 ? 212.015 247.833 159.094 1.00 63.12  ? 571 PRO B C   1 
ATOM   10602 O  O   . PRO B 1 571 ? 213.129 247.540 158.654 1.00 62.78  ? 571 PRO B O   1 
ATOM   10603 C  CB  . PRO B 1 571 ? 211.770 250.337 159.127 1.00 56.24  ? 571 PRO B CB  1 
ATOM   10604 C  CG  . PRO B 1 571 ? 212.583 251.320 159.872 1.00 60.90  ? 571 PRO B CG  1 
ATOM   10605 C  CD  . PRO B 1 571 ? 213.623 250.524 160.572 1.00 58.54  ? 571 PRO B CD  1 
ATOM   10606 N  N   . GLN B 1 572 ? 210.911 247.130 158.832 1.00 67.70  ? 572 GLN B N   1 
ATOM   10607 C  CA  . GLN B 1 572 ? 210.830 245.990 157.929 1.00 65.17  ? 572 GLN B CA  1 
ATOM   10608 C  C   . GLN B 1 572 ? 209.786 246.307 156.868 1.00 63.36  ? 572 GLN B C   1 
ATOM   10609 O  O   . GLN B 1 572 ? 208.690 246.784 157.196 1.00 62.17  ? 572 GLN B O   1 
ATOM   10610 C  CB  . GLN B 1 572 ? 210.436 244.717 158.680 1.00 59.49  ? 572 GLN B CB  1 
ATOM   10611 C  CG  . GLN B 1 572 ? 209.337 244.938 159.712 1.00 62.15  ? 572 GLN B CG  1 
ATOM   10612 C  CD  . GLN B 1 572 ? 209.033 243.704 160.533 1.00 64.45  ? 572 GLN B CD  1 
ATOM   10613 O  OE1 . GLN B 1 572 ? 209.675 242.672 160.374 1.00 64.51  ? 572 GLN B OE1 1 
ATOM   10614 N  NE2 . GLN B 1 572 ? 208.036 243.798 161.403 1.00 62.40  ? 572 GLN B NE2 1 
ATOM   10615 N  N   . ILE B 1 573 ? 210.120 246.046 155.600 1.00 61.33  ? 573 ILE B N   1 
ATOM   10616 C  CA  . ILE B 1 573 ? 209.302 246.510 154.486 1.00 58.14  ? 573 ILE B CA  1 
ATOM   10617 C  C   . ILE B 1 573 ? 209.074 245.401 153.464 1.00 69.30  ? 573 ILE B C   1 
ATOM   10618 O  O   . ILE B 1 573 ? 209.801 244.408 153.412 1.00 71.63  ? 573 ILE B O   1 
ATOM   10619 C  CB  . ILE B 1 573 ? 209.927 247.724 153.775 1.00 55.40  ? 573 ILE B CB  1 
ATOM   10620 C  CG1 . ILE B 1 573 ? 211.061 247.266 152.875 1.00 56.97  ? 573 ILE B CG1 1 
ATOM   10621 C  CG2 . ILE B 1 573 ? 210.436 248.725 154.772 1.00 63.07  ? 573 ILE B CG2 1 
ATOM   10622 C  CD1 . ILE B 1 573 ? 211.748 248.405 152.165 1.00 69.10  ? 573 ILE B CD1 1 
ATOM   10623 N  N   . PHE B 1 574 ? 208.053 245.602 152.627 1.00 70.85  ? 574 PHE B N   1 
ATOM   10624 C  CA  . PHE B 1 574 ? 207.765 244.689 151.528 1.00 58.57  ? 574 PHE B CA  1 
ATOM   10625 C  C   . PHE B 1 574 ? 208.889 244.707 150.503 1.00 56.81  ? 574 PHE B C   1 
ATOM   10626 O  O   . PHE B 1 574 ? 209.550 245.726 150.290 1.00 62.79  ? 574 PHE B O   1 
ATOM   10627 C  CB  . PHE B 1 574 ? 206.459 245.066 150.839 1.00 53.74  ? 574 PHE B CB  1 
ATOM   10628 C  CG  . PHE B 1 574 ? 205.238 244.830 151.670 1.00 51.95  ? 574 PHE B CG  1 
ATOM   10629 C  CD1 . PHE B 1 574 ? 204.821 245.758 152.593 1.00 55.21  ? 574 PHE B CD1 1 
ATOM   10630 C  CD2 . PHE B 1 574 ? 204.487 243.690 151.499 1.00 56.85  ? 574 PHE B CD2 1 
ATOM   10631 C  CE1 . PHE B 1 574 ? 203.693 245.548 153.339 1.00 54.20  ? 574 PHE B CE1 1 
ATOM   10632 C  CE2 . PHE B 1 574 ? 203.357 243.479 152.247 1.00 58.75  ? 574 PHE B CE2 1 
ATOM   10633 C  CZ  . PHE B 1 574 ? 202.960 244.417 153.168 1.00 54.42  ? 574 PHE B CZ  1 
ATOM   10634 N  N   . ALA B 1 575 ? 209.105 243.565 149.867 1.00 50.16  ? 575 ALA B N   1 
ATOM   10635 C  CA  . ALA B 1 575 ? 210.148 243.427 148.864 1.00 53.39  ? 575 ALA B CA  1 
ATOM   10636 C  C   . ALA B 1 575 ? 209.662 243.724 147.457 1.00 60.77  ? 575 ALA B C   1 
ATOM   10637 O  O   . ALA B 1 575 ? 210.471 243.719 146.528 1.00 58.88  ? 575 ALA B O   1 
ATOM   10638 C  CB  . ALA B 1 575 ? 210.736 242.019 148.906 1.00 54.52  ? 575 ALA B CB  1 
ATOM   10639 N  N   . GLU B 1 576 ? 208.363 243.971 147.275 1.00 68.76  ? 576 GLU B N   1 
ATOM   10640 C  CA  . GLU B 1 576 ? 207.795 244.271 145.964 1.00 67.95  ? 576 GLU B CA  1 
ATOM   10641 C  C   . GLU B 1 576 ? 207.582 245.767 145.764 1.00 67.66  ? 576 GLU B C   1 
ATOM   10642 O  O   . GLU B 1 576 ? 208.114 246.355 144.820 1.00 69.93  ? 576 GLU B O   1 
ATOM   10643 C  CB  . GLU B 1 576 ? 206.469 243.523 145.782 1.00 69.78  ? 576 GLU B CB  1 
ATOM   10644 C  CG  . GLU B 1 576 ? 206.608 242.116 145.239 1.00 70.66  ? 576 GLU B CG  1 
ATOM   10645 C  CD  . GLU B 1 576 ? 207.832 241.947 144.366 1.00 74.49  ? 576 GLU B CD  1 
ATOM   10646 O  OE1 . GLU B 1 576 ? 207.765 242.299 143.170 1.00 78.92  ? 576 GLU B OE1 1 
ATOM   10647 O  OE2 . GLU B 1 576 ? 208.861 241.457 144.875 1.00 75.03  ? 576 GLU B OE2 1 
ATOM   10648 N  N   . THR B 1 577 ? 206.808 246.397 146.645 1.00 68.82  ? 577 THR B N   1 
ATOM   10649 C  CA  . THR B 1 577 ? 206.455 247.798 146.489 1.00 73.54  ? 577 THR B CA  1 
ATOM   10650 C  C   . THR B 1 577 ? 207.236 248.736 147.396 1.00 71.78  ? 577 THR B C   1 
ATOM   10651 O  O   . THR B 1 577 ? 207.304 249.934 147.103 1.00 75.02  ? 577 THR B O   1 
ATOM   10652 C  CB  . THR B 1 577 ? 204.959 247.999 146.750 1.00 77.25  ? 577 THR B CB  1 
ATOM   10653 O  OG1 . THR B 1 577 ? 204.657 249.400 146.736 1.00 79.69  ? 577 THR B OG1 1 
ATOM   10654 C  CG2 . THR B 1 577 ? 204.574 247.414 148.095 1.00 73.19  ? 577 THR B CG2 1 
ATOM   10655 N  N   . GLY B 1 578 ? 207.816 248.236 148.481 1.00 68.28  ? 578 GLY B N   1 
ATOM   10656 C  CA  . GLY B 1 578 ? 208.569 249.073 149.388 1.00 69.40  ? 578 GLY B CA  1 
ATOM   10657 C  C   . GLY B 1 578 ? 207.739 249.863 150.373 1.00 70.79  ? 578 GLY B C   1 
ATOM   10658 O  O   . GLY B 1 578 ? 208.310 250.602 151.184 1.00 75.21  ? 578 GLY B O   1 
ATOM   10659 N  N   . GLU B 1 579 ? 206.418 249.742 150.324 1.00 69.53  ? 579 GLU B N   1 
ATOM   10660 C  CA  . GLU B 1 579 ? 205.563 250.365 151.321 1.00 69.61  ? 579 GLU B CA  1 
ATOM   10661 C  C   . GLU B 1 579 ? 205.868 249.767 152.688 1.00 67.07  ? 579 GLU B C   1 
ATOM   10662 O  O   . GLU B 1 579 ? 206.280 248.611 152.806 1.00 66.40  ? 579 GLU B O   1 
ATOM   10663 C  CB  . GLU B 1 579 ? 204.093 250.144 150.945 1.00 71.40  ? 579 GLU B CB  1 
ATOM   10664 C  CG  . GLU B 1 579 ? 202.998 250.543 151.948 1.00 75.74  ? 579 GLU B CG  1 
ATOM   10665 C  CD  . GLU B 1 579 ? 203.279 251.800 152.764 1.00 84.50  ? 579 GLU B CD  1 
ATOM   10666 O  OE1 . GLU B 1 579 ? 203.979 252.713 152.275 1.00 85.14  ? 579 GLU B OE1 1 
ATOM   10667 O  OE2 . GLU B 1 579 ? 202.793 251.872 153.911 1.00 85.28  ? 579 GLU B OE2 1 
ATOM   10668 N  N   . LEU B 1 580 ? 205.695 250.574 153.724 1.00 68.09  ? 580 LEU B N   1 
ATOM   10669 C  CA  . LEU B 1 580 ? 206.054 250.163 155.073 1.00 67.23  ? 580 LEU B CA  1 
ATOM   10670 C  C   . LEU B 1 580 ? 205.172 249.011 155.540 1.00 66.20  ? 580 LEU B C   1 
ATOM   10671 O  O   . LEU B 1 580 ? 203.955 249.164 155.662 1.00 67.09  ? 580 LEU B O   1 
ATOM   10672 C  CB  . LEU B 1 580 ? 205.929 251.351 156.020 1.00 67.33  ? 580 LEU B CB  1 
ATOM   10673 C  CG  . LEU B 1 580 ? 206.701 251.284 157.331 1.00 65.24  ? 580 LEU B CG  1 
ATOM   10674 C  CD1 . LEU B 1 580 ? 208.116 250.795 157.092 1.00 63.77  ? 580 LEU B CD1 1 
ATOM   10675 C  CD2 . LEU B 1 580 ? 206.710 252.639 158.005 1.00 72.89  ? 580 LEU B CD2 1 
ATOM   10676 N  N   . TYR B 1 581 ? 205.788 247.859 155.810 1.00 63.39  ? 581 TYR B N   1 
ATOM   10677 C  CA  . TYR B 1 581 ? 205.091 246.798 156.524 1.00 62.16  ? 581 TYR B CA  1 
ATOM   10678 C  C   . TYR B 1 581 ? 205.002 247.139 158.003 1.00 64.81  ? 581 TYR B C   1 
ATOM   10679 O  O   . TYR B 1 581 ? 203.906 247.298 158.551 1.00 64.38  ? 581 TYR B O   1 
ATOM   10680 C  CB  . TYR B 1 581 ? 205.811 245.458 156.350 1.00 64.56  ? 581 TYR B CB  1 
ATOM   10681 C  CG  . TYR B 1 581 ? 205.119 244.241 156.978 1.00 67.60  ? 581 TYR B CG  1 
ATOM   10682 C  CD1 . TYR B 1 581 ? 204.021 244.368 157.825 1.00 69.95  ? 581 TYR B CD1 1 
ATOM   10683 C  CD2 . TYR B 1 581 ? 205.629 242.974 156.790 1.00 62.18  ? 581 TYR B CD2 1 
ATOM   10684 C  CE1 . TYR B 1 581 ? 203.428 243.270 158.401 1.00 71.32  ? 581 TYR B CE1 1 
ATOM   10685 C  CE2 . TYR B 1 581 ? 205.051 241.881 157.356 1.00 61.84  ? 581 TYR B CE2 1 
ATOM   10686 C  CZ  . TYR B 1 581 ? 203.952 242.026 158.164 1.00 66.77  ? 581 TYR B CZ  1 
ATOM   10687 O  OH  . TYR B 1 581 ? 203.371 240.918 158.737 1.00 65.81  ? 581 TYR B OH  1 
ATOM   10688 N  N   . GLY B 1 582 ? 206.145 247.226 158.672 1.00 65.54  ? 582 GLY B N   1 
ATOM   10689 C  CA  . GLY B 1 582 ? 206.112 247.431 160.107 1.00 63.68  ? 582 GLY B CA  1 
ATOM   10690 C  C   . GLY B 1 582 ? 207.484 247.785 160.620 1.00 59.45  ? 582 GLY B C   1 
ATOM   10691 O  O   . GLY B 1 582 ? 208.421 248.001 159.852 1.00 60.83  ? 582 GLY B O   1 
ATOM   10692 N  N   . ILE B 1 583 ? 207.585 247.867 161.940 1.00 53.08  ? 583 ILE B N   1 
ATOM   10693 C  CA  . ILE B 1 583 ? 208.820 248.239 162.615 1.00 49.94  ? 583 ILE B CA  1 
ATOM   10694 C  C   . ILE B 1 583 ? 208.892 247.457 163.916 1.00 54.87  ? 583 ILE B C   1 
ATOM   10695 O  O   . ILE B 1 583 ? 207.912 247.410 164.661 1.00 57.57  ? 583 ILE B O   1 
ATOM   10696 C  CB  . ILE B 1 583 ? 208.871 249.750 162.899 1.00 52.08  ? 583 ILE B CB  1 
ATOM   10697 C  CG1 . ILE B 1 583 ? 207.555 250.209 163.521 1.00 54.16  ? 583 ILE B CG1 1 
ATOM   10698 C  CG2 . ILE B 1 583 ? 209.135 250.540 161.635 1.00 57.21  ? 583 ILE B CG2 1 
ATOM   10699 C  CD1 . ILE B 1 583 ? 207.655 251.505 164.268 1.00 56.52  ? 583 ILE B CD1 1 
ATOM   10700 N  N   . GLU B 1 584 ? 210.030 246.833 164.197 1.00 57.02  ? 584 GLU B N   1 
ATOM   10701 C  CA  . GLU B 1 584 ? 210.168 246.216 165.506 1.00 54.65  ? 584 GLU B CA  1 
ATOM   10702 C  C   . GLU B 1 584 ? 210.678 247.208 166.535 1.00 50.63  ? 584 GLU B C   1 
ATOM   10703 O  O   . GLU B 1 584 ? 211.450 248.120 166.229 1.00 54.74  ? 584 GLU B O   1 
ATOM   10704 C  CB  . GLU B 1 584 ? 211.079 244.982 165.533 1.00 60.41  ? 584 GLU B CB  1 
ATOM   10705 C  CG  . GLU B 1 584 ? 210.857 243.902 164.501 1.00 68.22  ? 584 GLU B CG  1 
ATOM   10706 C  CD  . GLU B 1 584 ? 212.018 242.926 164.450 1.00 74.70  ? 584 GLU B CD  1 
ATOM   10707 O  OE1 . GLU B 1 584 ? 212.288 242.348 163.384 1.00 72.64  ? 584 GLU B OE1 1 
ATOM   10708 O  OE2 . GLU B 1 584 ? 212.671 242.733 165.497 1.00 75.06  ? 584 GLU B OE2 1 
ATOM   10709 N  N   . ALA B 1 585 ? 210.232 247.002 167.770 1.00 50.03  ? 585 ALA B N   1 
ATOM   10710 C  CA  . ALA B 1 585 ? 210.679 247.747 168.935 1.00 52.84  ? 585 ALA B CA  1 
ATOM   10711 C  C   . ALA B 1 585 ? 211.644 246.879 169.731 1.00 50.22  ? 585 ALA B C   1 
ATOM   10712 O  O   . ALA B 1 585 ? 211.296 245.764 170.129 1.00 48.54  ? 585 ALA B O   1 
ATOM   10713 C  CB  . ALA B 1 585 ? 209.491 248.159 169.800 1.00 52.59  ? 585 ALA B CB  1 
ATOM   10714 N  N   . LEU B 1 586 ? 212.843 247.394 169.976 1.00 48.31  ? 586 LEU B N   1 
ATOM   10715 C  CA  . LEU B 1 586 ? 213.886 246.665 170.674 1.00 45.90  ? 586 LEU B CA  1 
ATOM   10716 C  C   . LEU B 1 586 ? 214.380 247.500 171.845 1.00 46.45  ? 586 LEU B C   1 
ATOM   10717 O  O   . LEU B 1 586 ? 214.675 248.687 171.683 1.00 49.94  ? 586 LEU B O   1 
ATOM   10718 C  CB  . LEU B 1 586 ? 215.045 246.352 169.733 1.00 47.65  ? 586 LEU B CB  1 
ATOM   10719 C  CG  . LEU B 1 586 ? 214.716 245.780 168.359 1.00 48.30  ? 586 LEU B CG  1 
ATOM   10720 C  CD1 . LEU B 1 586 ? 214.641 246.875 167.321 1.00 48.16  ? 586 LEU B CD1 1 
ATOM   10721 C  CD2 . LEU B 1 586 ? 215.764 244.759 167.962 1.00 49.78  ? 586 LEU B CD2 1 
ATOM   10722 N  N   . ALA B 1 587 ? 214.480 246.880 173.014 1.00 42.99  ? 587 ALA B N   1 
ATOM   10723 C  CA  . ALA B 1 587 ? 214.994 247.573 174.182 1.00 43.05  ? 587 ALA B CA  1 
ATOM   10724 C  C   . ALA B 1 587 ? 216.469 247.908 174.007 1.00 41.73  ? 587 ALA B C   1 
ATOM   10725 O  O   . ALA B 1 587 ? 217.225 247.175 173.368 1.00 42.66  ? 587 ALA B O   1 
ATOM   10726 C  CB  . ALA B 1 587 ? 214.794 246.721 175.432 1.00 44.64  ? 587 ALA B CB  1 
ATOM   10727 N  N   . ARG B 1 588 ? 216.866 249.049 174.562 1.00 40.28  ? 588 ARG B N   1 
ATOM   10728 C  CA  . ARG B 1 588 ? 218.244 249.505 174.543 1.00 39.31  ? 588 ARG B CA  1 
ATOM   10729 C  C   . ARG B 1 588 ? 218.503 250.292 175.814 1.00 45.01  ? 588 ARG B C   1 
ATOM   10730 O  O   . ARG B 1 588 ? 217.618 250.988 176.321 1.00 51.68  ? 588 ARG B O   1 
ATOM   10731 C  CB  . ARG B 1 588 ? 218.538 250.383 173.333 1.00 42.24  ? 588 ARG B CB  1 
ATOM   10732 C  CG  . ARG B 1 588 ? 218.678 249.626 172.043 1.00 42.61  ? 588 ARG B CG  1 
ATOM   10733 C  CD  . ARG B 1 588 ? 220.046 249.040 171.905 1.00 38.14  ? 588 ARG B CD  1 
ATOM   10734 N  NE  . ARG B 1 588 ? 220.254 248.503 170.570 1.00 39.14  ? 588 ARG B NE  1 
ATOM   10735 C  CZ  . ARG B 1 588 ? 219.767 247.346 170.153 1.00 45.00  ? 588 ARG B CZ  1 
ATOM   10736 N  NH1 . ARG B 1 588 ? 219.046 246.575 170.946 1.00 47.43  ? 588 ARG B NH1 1 
ATOM   10737 N  NH2 . ARG B 1 588 ? 220.012 246.950 168.909 1.00 46.71  ? 588 ARG B NH2 1 
ATOM   10738 N  N   . TRP B 1 589 ? 219.725 250.177 176.320 1.00 45.75  ? 589 TRP B N   1 
ATOM   10739 C  CA  . TRP B 1 589 ? 220.110 250.821 177.566 1.00 50.85  ? 589 TRP B CA  1 
ATOM   10740 C  C   . TRP B 1 589 ? 221.511 251.376 177.405 1.00 56.18  ? 589 TRP B C   1 
ATOM   10741 O  O   . TRP B 1 589 ? 222.452 250.618 177.156 1.00 55.98  ? 589 TRP B O   1 
ATOM   10742 C  CB  . TRP B 1 589 ? 220.062 249.837 178.732 1.00 54.60  ? 589 TRP B CB  1 
ATOM   10743 C  CG  . TRP B 1 589 ? 220.338 250.443 180.065 1.00 55.87  ? 589 TRP B CG  1 
ATOM   10744 C  CD1 . TRP B 1 589 ? 220.091 251.722 180.451 1.00 58.13  ? 589 TRP B CD1 1 
ATOM   10745 C  CD2 . TRP B 1 589 ? 220.918 249.789 181.196 1.00 54.19  ? 589 TRP B CD2 1 
ATOM   10746 N  NE1 . TRP B 1 589 ? 220.475 251.905 181.755 1.00 58.84  ? 589 TRP B NE1 1 
ATOM   10747 C  CE2 . TRP B 1 589 ? 220.988 250.729 182.231 1.00 57.30  ? 589 TRP B CE2 1 
ATOM   10748 C  CE3 . TRP B 1 589 ? 221.373 248.496 181.434 1.00 53.85  ? 589 TRP B CE3 1 
ATOM   10749 C  CZ2 . TRP B 1 589 ? 221.496 250.418 183.476 1.00 62.08  ? 589 TRP B CZ2 1 
ATOM   10750 C  CZ3 . TRP B 1 589 ? 221.884 248.195 182.661 1.00 54.25  ? 589 TRP B CZ3 1 
ATOM   10751 C  CH2 . TRP B 1 589 ? 221.940 249.146 183.670 1.00 60.07  ? 589 TRP B CH2 1 
ATOM   10752 N  N   . HIS B 1 590 ? 221.648 252.692 177.532 1.00 62.96  ? 590 HIS B N   1 
ATOM   10753 C  CA  . HIS B 1 590 ? 222.946 253.344 177.610 1.00 63.43  ? 590 HIS B CA  1 
ATOM   10754 C  C   . HIS B 1 590 ? 223.053 254.031 178.960 1.00 68.37  ? 590 HIS B C   1 
ATOM   10755 O  O   . HIS B 1 590 ? 222.178 254.821 179.329 1.00 70.36  ? 590 HIS B O   1 
ATOM   10756 C  CB  . HIS B 1 590 ? 223.141 254.366 176.501 1.00 58.67  ? 590 HIS B CB  1 
ATOM   10757 C  CG  . HIS B 1 590 ? 223.897 255.576 176.941 1.00 66.32  ? 590 HIS B CG  1 
ATOM   10758 N  ND1 . HIS B 1 590 ? 225.259 255.565 177.139 1.00 68.92  ? 590 HIS B ND1 1 
ATOM   10759 C  CD2 . HIS B 1 590 ? 223.484 256.831 177.233 1.00 73.94  ? 590 HIS B CD2 1 
ATOM   10760 C  CE1 . HIS B 1 590 ? 225.655 256.762 177.530 1.00 72.99  ? 590 HIS B CE1 1 
ATOM   10761 N  NE2 . HIS B 1 590 ? 224.597 257.550 177.594 1.00 76.94  ? 590 HIS B NE2 1 
ATOM   10762 N  N   . ASP B 1 591 ? 224.121 253.732 179.693 1.00 72.50  ? 591 ASP B N   1 
ATOM   10763 C  CA  . ASP B 1 591 ? 224.251 254.222 181.051 1.00 77.93  ? 591 ASP B CA  1 
ATOM   10764 C  C   . ASP B 1 591 ? 225.472 255.122 181.185 1.00 79.31  ? 591 ASP B C   1 
ATOM   10765 O  O   . ASP B 1 591 ? 226.530 254.810 180.634 1.00 78.37  ? 591 ASP B O   1 
ATOM   10766 C  CB  . ASP B 1 591 ? 224.366 253.052 182.039 1.00 75.95  ? 591 ASP B CB  1 
ATOM   10767 C  CG  . ASP B 1 591 ? 224.404 253.508 183.477 1.00 79.14  ? 591 ASP B CG  1 
ATOM   10768 O  OD1 . ASP B 1 591 ? 223.356 253.958 183.986 1.00 79.09  ? 591 ASP B OD1 1 
ATOM   10769 O  OD2 . ASP B 1 591 ? 225.480 253.414 184.100 1.00 80.29  ? 591 ASP B OD2 1 
ATOM   10770 N  N   . PRO B 1 592 ? 225.358 256.248 181.895 1.00 77.86  ? 592 PRO B N   1 
ATOM   10771 C  CA  . PRO B 1 592 ? 226.539 257.106 182.071 1.00 76.74  ? 592 PRO B CA  1 
ATOM   10772 C  C   . PRO B 1 592 ? 227.698 256.393 182.735 1.00 75.32  ? 592 PRO B C   1 
ATOM   10773 O  O   . PRO B 1 592 ? 228.854 256.599 182.351 1.00 75.33  ? 592 PRO B O   1 
ATOM   10774 C  CB  . PRO B 1 592 ? 226.005 258.250 182.944 1.00 78.40  ? 592 PRO B CB  1 
ATOM   10775 C  CG  . PRO B 1 592 ? 224.795 257.684 183.614 1.00 75.72  ? 592 PRO B CG  1 
ATOM   10776 C  CD  . PRO B 1 592 ? 224.183 256.778 182.603 1.00 75.70  ? 592 PRO B CD  1 
ATOM   10777 N  N   . LEU B 1 593 ? 227.414 255.539 183.714 1.00 73.25  ? 593 LEU B N   1 
ATOM   10778 C  CA  . LEU B 1 593 ? 228.463 254.842 184.442 1.00 75.88  ? 593 LEU B CA  1 
ATOM   10779 C  C   . LEU B 1 593 ? 228.914 253.573 183.742 1.00 78.28  ? 593 LEU B C   1 
ATOM   10780 O  O   . LEU B 1 593 ? 230.074 253.172 183.890 1.00 80.47  ? 593 LEU B O   1 
ATOM   10781 C  CB  . LEU B 1 593 ? 227.984 254.499 185.853 1.00 79.43  ? 593 LEU B CB  1 
ATOM   10782 C  CG  . LEU B 1 593 ? 229.064 254.358 186.924 1.00 85.52  ? 593 LEU B CG  1 
ATOM   10783 C  CD1 . LEU B 1 593 ? 230.099 255.463 186.795 1.00 81.00  ? 593 LEU B CD1 1 
ATOM   10784 C  CD2 . LEU B 1 593 ? 228.439 254.366 188.309 1.00 84.58  ? 593 LEU B CD2 1 
ATOM   10785 N  N   . HIS B 1 594 ? 228.029 252.935 182.979 1.00 75.82  ? 594 HIS B N   1 
ATOM   10786 C  CA  . HIS B 1 594 ? 228.349 251.675 182.335 1.00 70.44  ? 594 HIS B CA  1 
ATOM   10787 C  C   . HIS B 1 594 ? 228.289 251.724 180.819 1.00 72.64  ? 594 HIS B C   1 
ATOM   10788 O  O   . HIS B 1 594 ? 228.636 250.729 180.175 1.00 74.19  ? 594 HIS B O   1 
ATOM   10789 C  CB  . HIS B 1 594 ? 227.418 250.575 182.847 1.00 65.94  ? 594 HIS B CB  1 
ATOM   10790 C  CG  . HIS B 1 594 ? 227.750 250.110 184.226 1.00 66.47  ? 594 HIS B CG  1 
ATOM   10791 N  ND1 . HIS B 1 594 ? 228.791 249.248 184.487 1.00 69.70  ? 594 HIS B ND1 1 
ATOM   10792 C  CD2 . HIS B 1 594 ? 227.185 250.392 185.421 1.00 69.93  ? 594 HIS B CD2 1 
ATOM   10793 C  CE1 . HIS B 1 594 ? 228.850 249.015 185.784 1.00 74.59  ? 594 HIS B CE1 1 
ATOM   10794 N  NE2 . HIS B 1 594 ? 227.884 249.695 186.373 1.00 74.28  ? 594 HIS B NE2 1 
ATOM   10795 N  N   . GLY B 1 595 ? 227.877 252.841 180.229 1.00 74.36  ? 595 GLY B N   1 
ATOM   10796 C  CA  . GLY B 1 595 ? 227.927 252.924 178.784 1.00 76.03  ? 595 GLY B CA  1 
ATOM   10797 C  C   . GLY B 1 595 ? 226.873 252.056 178.122 1.00 76.19  ? 595 GLY B C   1 
ATOM   10798 O  O   . GLY B 1 595 ? 225.800 251.790 178.672 1.00 75.06  ? 595 GLY B O   1 
ATOM   10799 N  N   . HIS B 1 596 ? 227.188 251.614 176.911 1.00 71.84  ? 596 HIS B N   1 
ATOM   10800 C  CA  . HIS B 1 596 ? 226.275 250.776 176.152 1.00 61.70  ? 596 HIS B CA  1 
ATOM   10801 C  C   . HIS B 1 596 ? 226.358 249.342 176.649 1.00 59.88  ? 596 HIS B C   1 
ATOM   10802 O  O   . HIS B 1 596 ? 227.449 248.774 176.747 1.00 64.05  ? 596 HIS B O   1 
ATOM   10803 C  CB  . HIS B 1 596 ? 226.620 250.842 174.669 1.00 56.13  ? 596 HIS B CB  1 
ATOM   10804 C  CG  . HIS B 1 596 ? 226.352 252.176 174.050 1.00 60.92  ? 596 HIS B CG  1 
ATOM   10805 N  ND1 . HIS B 1 596 ? 225.092 252.581 173.670 1.00 68.35  ? 596 HIS B ND1 1 
ATOM   10806 C  CD2 . HIS B 1 596 ? 227.182 253.202 173.754 1.00 61.56  ? 596 HIS B CD2 1 
ATOM   10807 C  CE1 . HIS B 1 596 ? 225.158 253.798 173.161 1.00 69.17  ? 596 HIS B CE1 1 
ATOM   10808 N  NE2 . HIS B 1 596 ? 226.416 254.197 173.200 1.00 64.43  ? 596 HIS B NE2 1 
ATOM   10809 N  N   . VAL B 1 597 ? 225.209 248.753 176.960 1.00 56.11  ? 597 VAL B N   1 
ATOM   10810 C  CA  . VAL B 1 597 ? 225.166 247.342 177.326 1.00 54.17  ? 597 VAL B CA  1 
ATOM   10811 C  C   . VAL B 1 597 ? 224.017 246.676 176.575 1.00 51.34  ? 597 VAL B C   1 
ATOM   10812 O  O   . VAL B 1 597 ? 222.870 247.135 176.644 1.00 52.96  ? 597 VAL B O   1 
ATOM   10813 C  CB  . VAL B 1 597 ? 225.074 247.170 178.849 1.00 54.61  ? 597 VAL B CB  1 
ATOM   10814 C  CG1 . VAL B 1 597 ? 223.818 247.782 179.382 1.00 53.44  ? 597 VAL B CG1 1 
ATOM   10815 C  CG2 . VAL B 1 597 ? 225.147 245.703 179.222 1.00 56.42  ? 597 VAL B CG2 1 
ATOM   10816 N  N   . PRO B 1 598 ? 224.289 245.619 175.821 1.00 49.03  ? 598 PRO B N   1 
ATOM   10817 C  CA  . PRO B 1 598 ? 223.308 245.103 174.872 1.00 50.62  ? 598 PRO B CA  1 
ATOM   10818 C  C   . PRO B 1 598 ? 222.181 244.375 175.576 1.00 54.25  ? 598 PRO B C   1 
ATOM   10819 O  O   . PRO B 1 598 ? 222.315 243.985 176.743 1.00 61.87  ? 598 PRO B O   1 
ATOM   10820 C  CB  . PRO B 1 598 ? 224.134 244.146 174.004 1.00 55.08  ? 598 PRO B CB  1 
ATOM   10821 C  CG  . PRO B 1 598 ? 225.246 243.727 174.875 1.00 54.77  ? 598 PRO B CG  1 
ATOM   10822 C  CD  . PRO B 1 598 ? 225.565 244.895 175.749 1.00 51.29  ? 598 PRO B CD  1 
ATOM   10823 N  N   . PRO B 1 599 ? 221.048 244.184 174.900 1.00 49.90  ? 599 PRO B N   1 
ATOM   10824 C  CA  . PRO B 1 599 ? 219.966 243.394 175.499 1.00 56.46  ? 599 PRO B CA  1 
ATOM   10825 C  C   . PRO B 1 599 ? 220.362 241.964 175.801 1.00 66.55  ? 599 PRO B C   1 
ATOM   10826 O  O   . PRO B 1 599 ? 219.914 241.404 176.812 1.00 71.04  ? 599 PRO B O   1 
ATOM   10827 C  CB  . PRO B 1 599 ? 218.858 243.465 174.444 1.00 53.52  ? 599 PRO B CB  1 
ATOM   10828 C  CG  . PRO B 1 599 ? 219.549 243.807 173.192 1.00 52.79  ? 599 PRO B CG  1 
ATOM   10829 C  CD  . PRO B 1 599 ? 220.686 244.687 173.571 1.00 51.26  ? 599 PRO B CD  1 
ATOM   10830 N  N   . SER B 1 600 ? 221.218 241.365 174.970 1.00 64.92  ? 600 SER B N   1 
ATOM   10831 C  CA  . SER B 1 600 ? 221.649 239.995 175.202 1.00 67.31  ? 600 SER B CA  1 
ATOM   10832 C  C   . SER B 1 600 ? 222.407 239.853 176.507 1.00 67.55  ? 600 SER B C   1 
ATOM   10833 O  O   . SER B 1 600 ? 222.591 238.732 176.988 1.00 73.44  ? 600 SER B O   1 
ATOM   10834 C  CB  . SER B 1 600 ? 222.532 239.517 174.056 1.00 69.00  ? 600 SER B CB  1 
ATOM   10835 O  OG  . SER B 1 600 ? 223.881 239.870 174.295 1.00 70.51  ? 600 SER B OG  1 
ATOM   10836 N  N   . ARG B 1 601 ? 222.860 240.961 177.084 1.00 61.01  ? 601 ARG B N   1 
ATOM   10837 C  CA  . ARG B 1 601 ? 223.566 240.934 178.354 1.00 60.89  ? 601 ARG B CA  1 
ATOM   10838 C  C   . ARG B 1 601 ? 222.651 241.256 179.524 1.00 60.47  ? 601 ARG B C   1 
ATOM   10839 O  O   . ARG B 1 601 ? 222.712 240.593 180.560 1.00 68.09  ? 601 ARG B O   1 
ATOM   10840 C  CB  . ARG B 1 601 ? 224.740 241.916 178.320 1.00 64.87  ? 601 ARG B CB  1 
ATOM   10841 C  CG  . ARG B 1 601 ? 225.491 242.050 179.632 1.00 72.02  ? 601 ARG B CG  1 
ATOM   10842 C  CD  . ARG B 1 601 ? 226.035 240.710 180.095 1.00 75.64  ? 601 ARG B CD  1 
ATOM   10843 N  NE  . ARG B 1 601 ? 226.955 240.851 181.217 1.00 81.21  ? 601 ARG B NE  1 
ATOM   10844 C  CZ  . ARG B 1 601 ? 226.586 241.048 182.475 1.00 81.32  ? 601 ARG B CZ  1 
ATOM   10845 N  NH1 . ARG B 1 601 ? 225.311 241.129 182.818 1.00 75.80  ? 601 ARG B NH1 1 
ATOM   10846 N  NH2 . ARG B 1 601 ? 227.521 241.167 183.414 1.00 82.66  ? 601 ARG B NH2 1 
ATOM   10847 N  N   . PHE B 1 602 ? 221.801 242.262 179.382 1.00 56.31  ? 602 PHE B N   1 
ATOM   10848 C  CA  . PHE B 1 602 ? 221.028 242.721 180.518 1.00 63.71  ? 602 PHE B CA  1 
ATOM   10849 C  C   . PHE B 1 602 ? 219.664 242.055 180.631 1.00 69.07  ? 602 PHE B C   1 
ATOM   10850 O  O   . PHE B 1 602 ? 218.969 242.282 181.625 1.00 74.64  ? 602 PHE B O   1 
ATOM   10851 C  CB  . PHE B 1 602 ? 220.905 244.253 180.480 1.00 60.85  ? 602 PHE B CB  1 
ATOM   10852 C  CG  . PHE B 1 602 ? 219.713 244.768 179.741 1.00 58.82  ? 602 PHE B CG  1 
ATOM   10853 C  CD1 . PHE B 1 602 ? 218.525 245.005 180.391 1.00 61.40  ? 602 PHE B CD1 1 
ATOM   10854 C  CD2 . PHE B 1 602 ? 219.796 245.061 178.408 1.00 54.91  ? 602 PHE B CD2 1 
ATOM   10855 C  CE1 . PHE B 1 602 ? 217.442 245.482 179.711 1.00 62.62  ? 602 PHE B CE1 1 
ATOM   10856 C  CE2 . PHE B 1 602 ? 218.719 245.540 177.733 1.00 53.16  ? 602 PHE B CE2 1 
ATOM   10857 C  CZ  . PHE B 1 602 ? 217.542 245.752 178.381 1.00 58.62  ? 602 PHE B CZ  1 
ATOM   10858 N  N   . ILE B 1 603 ? 219.271 241.224 179.670 1.00 65.02  ? 603 ILE B N   1 
ATOM   10859 C  CA  . ILE B 1 603 ? 218.066 240.412 179.839 1.00 64.26  ? 603 ILE B CA  1 
ATOM   10860 C  C   . ILE B 1 603 ? 218.387 239.198 180.706 1.00 68.50  ? 603 ILE B C   1 
ATOM   10861 O  O   . ILE B 1 603 ? 217.652 238.928 181.671 1.00 71.65  ? 603 ILE B O   1 
ATOM   10862 C  CB  . ILE B 1 603 ? 217.465 240.005 178.486 1.00 62.27  ? 603 ILE B CB  1 
ATOM   10863 C  CG1 . ILE B 1 603 ? 216.732 241.186 177.864 1.00 62.27  ? 603 ILE B CG1 1 
ATOM   10864 C  CG2 . ILE B 1 603 ? 216.518 238.836 178.658 1.00 71.25  ? 603 ILE B CG2 1 
ATOM   10865 C  CD1 . ILE B 1 603 ? 215.503 241.587 178.626 1.00 69.67  ? 603 ILE B CD1 1 
ATOM   10866 N  N   . PRO B 1 604 ? 219.451 238.434 180.423 1.00 68.28  ? 604 PRO B N   1 
ATOM   10867 C  CA  . PRO B 1 604 ? 219.828 237.375 181.370 1.00 68.85  ? 604 PRO B CA  1 
ATOM   10868 C  C   . PRO B 1 604 ? 220.108 237.904 182.761 1.00 73.24  ? 604 PRO B C   1 
ATOM   10869 O  O   . PRO B 1 604 ? 219.750 237.257 183.751 1.00 76.71  ? 604 PRO B O   1 
ATOM   10870 C  CB  . PRO B 1 604 ? 221.081 236.768 180.730 1.00 64.83  ? 604 PRO B CB  1 
ATOM   10871 C  CG  . PRO B 1 604 ? 220.925 237.034 179.299 1.00 63.45  ? 604 PRO B CG  1 
ATOM   10872 C  CD  . PRO B 1 604 ? 220.280 238.376 179.207 1.00 67.34  ? 604 PRO B CD  1 
ATOM   10873 N  N   . LEU B 1 605 ? 220.734 239.076 182.869 1.00 71.79  ? 605 LEU B N   1 
ATOM   10874 C  CA  . LEU B 1 605 ? 220.933 239.660 184.187 1.00 68.71  ? 605 LEU B CA  1 
ATOM   10875 C  C   . LEU B 1 605 ? 219.596 239.954 184.836 1.00 70.10  ? 605 LEU B C   1 
ATOM   10876 O  O   . LEU B 1 605 ? 219.425 239.738 186.038 1.00 74.04  ? 605 LEU B O   1 
ATOM   10877 C  CB  . LEU B 1 605 ? 221.771 240.931 184.082 1.00 65.16  ? 605 LEU B CB  1 
ATOM   10878 C  CG  . LEU B 1 605 ? 221.661 242.028 185.142 1.00 69.19  ? 605 LEU B CG  1 
ATOM   10879 C  CD1 . LEU B 1 605 ? 221.902 241.494 186.550 1.00 69.02  ? 605 LEU B CD1 1 
ATOM   10880 C  CD2 . LEU B 1 605 ? 222.626 243.160 184.834 1.00 69.74  ? 605 LEU B CD2 1 
ATOM   10881 N  N   . ALA B 1 606 ? 218.632 240.431 184.051 1.00 71.13  ? 606 ALA B N   1 
ATOM   10882 C  CA  . ALA B 1 606 ? 217.316 240.718 184.601 1.00 77.66  ? 606 ALA B CA  1 
ATOM   10883 C  C   . ALA B 1 606 ? 216.676 239.460 185.163 1.00 79.46  ? 606 ALA B C   1 
ATOM   10884 O  O   . ALA B 1 606 ? 216.110 239.482 186.262 1.00 81.98  ? 606 ALA B O   1 
ATOM   10885 C  CB  . ALA B 1 606 ? 216.421 241.344 183.534 1.00 79.18  ? 606 ALA B CB  1 
ATOM   10886 N  N   . GLU B 1 607 ? 216.768 238.345 184.434 1.00 78.24  ? 607 GLU B N   1 
ATOM   10887 C  CA  . GLU B 1 607 ? 216.175 237.120 184.958 1.00 82.88  ? 607 GLU B CA  1 
ATOM   10888 C  C   . GLU B 1 607 ? 216.958 236.599 186.155 1.00 84.59  ? 607 GLU B C   1 
ATOM   10889 O  O   . GLU B 1 607 ? 216.386 235.933 187.025 1.00 85.39  ? 607 GLU B O   1 
ATOM   10890 C  CB  . GLU B 1 607 ? 216.048 236.062 183.853 1.00 86.70  ? 607 GLU B CB  1 
ATOM   10891 C  CG  . GLU B 1 607 ? 217.333 235.534 183.237 1.00 87.17  ? 607 GLU B CG  1 
ATOM   10892 C  CD  . GLU B 1 607 ? 218.098 234.578 184.135 1.00 95.16  ? 607 GLU B CD  1 
ATOM   10893 O  OE1 . GLU B 1 607 ? 219.327 234.447 183.955 1.00 93.42  ? 607 GLU B OE1 1 
ATOM   10894 O  OE2 . GLU B 1 607 ? 217.469 233.940 185.006 1.00 96.93  ? 607 GLU B OE2 1 
ATOM   10895 N  N   . GLU B 1 608 ? 218.259 236.894 186.224 1.00 85.03  ? 608 GLU B N   1 
ATOM   10896 C  CA  . GLU B 1 608 ? 219.004 236.592 187.441 1.00 85.51  ? 608 GLU B CA  1 
ATOM   10897 C  C   . GLU B 1 608 ? 218.433 237.363 188.621 1.00 88.28  ? 608 GLU B C   1 
ATOM   10898 O  O   . GLU B 1 608 ? 218.236 236.803 189.706 1.00 91.10  ? 608 GLU B O   1 
ATOM   10899 C  CB  . GLU B 1 608 ? 220.484 236.917 187.259 1.00 81.04  ? 608 GLU B CB  1 
ATOM   10900 C  CG  . GLU B 1 608 ? 221.291 236.809 188.539 1.00 79.44  ? 608 GLU B CG  1 
ATOM   10901 C  CD  . GLU B 1 608 ? 222.781 236.953 188.303 1.00 80.04  ? 608 GLU B CD  1 
ATOM   10902 O  OE1 . GLU B 1 608 ? 223.207 236.890 187.131 1.00 79.95  ? 608 GLU B OE1 1 
ATOM   10903 O  OE2 . GLU B 1 608 ? 223.527 237.124 189.289 1.00 79.21  ? 608 GLU B OE2 1 
ATOM   10904 N  N   . ILE B 1 609 ? 218.147 238.651 188.423 1.00 84.98  ? 609 ILE B N   1 
ATOM   10905 C  CA  . ILE B 1 609 ? 217.435 239.412 189.441 1.00 79.83  ? 609 ILE B CA  1 
ATOM   10906 C  C   . ILE B 1 609 ? 215.989 238.961 189.553 1.00 80.94  ? 609 ILE B C   1 
ATOM   10907 O  O   . ILE B 1 609 ? 215.359 239.171 190.596 1.00 81.06  ? 609 ILE B O   1 
ATOM   10908 C  CB  . ILE B 1 609 ? 217.503 240.917 189.142 1.00 78.79  ? 609 ILE B CB  1 
ATOM   10909 C  CG1 . ILE B 1 609 ? 218.928 241.313 188.769 1.00 79.87  ? 609 ILE B CG1 1 
ATOM   10910 C  CG2 . ILE B 1 609 ? 217.052 241.721 190.342 1.00 79.81  ? 609 ILE B CG2 1 
ATOM   10911 C  CD1 . ILE B 1 609 ? 219.931 241.076 189.867 1.00 79.60  ? 609 ILE B CD1 1 
ATOM   10912 N  N   . GLY B 1 610 ? 215.457 238.316 188.523 1.00 84.91  ? 610 GLY B N   1 
ATOM   10913 C  CA  . GLY B 1 610 ? 214.054 237.944 188.518 1.00 91.04  ? 610 GLY B CA  1 
ATOM   10914 C  C   . GLY B 1 610 ? 213.121 239.133 188.453 1.00 96.80  ? 610 GLY B C   1 
ATOM   10915 O  O   . GLY B 1 610 ? 212.071 239.130 189.108 1.00 100.39 ? 610 GLY B O   1 
ATOM   10916 N  N   . GLU B 1 611 ? 213.479 240.150 187.676 1.00 92.81  ? 611 GLU B N   1 
ATOM   10917 C  CA  . GLU B 1 611 ? 212.670 241.346 187.494 1.00 88.86  ? 611 GLU B CA  1 
ATOM   10918 C  C   . GLU B 1 611 ? 212.374 241.563 186.022 1.00 86.63  ? 611 GLU B C   1 
ATOM   10919 O  O   . GLU B 1 611 ? 212.363 242.694 185.530 1.00 90.16  ? 611 GLU B O   1 
ATOM   10920 C  CB  . GLU B 1 611 ? 213.358 242.571 188.086 1.00 88.08  ? 611 GLU B CB  1 
ATOM   10921 C  CG  . GLU B 1 611 ? 213.505 242.535 189.596 1.00 91.38  ? 611 GLU B CG  1 
ATOM   10922 C  CD  . GLU B 1 611 ? 212.237 242.953 190.313 1.00 94.19  ? 611 GLU B CD  1 
ATOM   10923 O  OE1 . GLU B 1 611 ? 211.534 243.850 189.803 1.00 93.05  ? 611 GLU B OE1 1 
ATOM   10924 O  OE2 . GLU B 1 611 ? 211.946 242.388 191.388 1.00 98.18  ? 611 GLU B OE2 1 
ATOM   10925 N  N   . ILE B 1 612 ? 212.137 240.473 185.291 1.00 82.41  ? 612 ILE B N   1 
ATOM   10926 C  CA  . ILE B 1 612 ? 211.869 240.594 183.865 1.00 84.67  ? 612 ILE B CA  1 
ATOM   10927 C  C   . ILE B 1 612 ? 210.504 241.213 183.613 1.00 87.19  ? 612 ILE B C   1 
ATOM   10928 O  O   . ILE B 1 612 ? 210.309 241.914 182.611 1.00 87.48  ? 612 ILE B O   1 
ATOM   10929 C  CB  . ILE B 1 612 ? 212.002 239.224 183.186 1.00 90.63  ? 612 ILE B CB  1 
ATOM   10930 C  CG1 . ILE B 1 612 ? 211.487 238.124 184.113 1.00 95.49  ? 612 ILE B CG1 1 
ATOM   10931 C  CG2 . ILE B 1 612 ? 213.445 238.969 182.797 1.00 88.15  ? 612 ILE B CG2 1 
ATOM   10932 C  CD1 . ILE B 1 612 ? 211.335 236.784 183.436 1.00 96.27  ? 612 ILE B CD1 1 
ATOM   10933 N  N   . GLU B 1 613 ? 209.539 240.973 184.502 1.00 90.33  ? 613 GLU B N   1 
ATOM   10934 C  CA  . GLU B 1 613 ? 208.198 241.497 184.276 1.00 91.51  ? 613 GLU B CA  1 
ATOM   10935 C  C   . GLU B 1 613 ? 208.205 243.013 184.217 1.00 86.05  ? 613 GLU B C   1 
ATOM   10936 O  O   . GLU B 1 613 ? 207.397 243.614 183.496 1.00 85.12  ? 613 GLU B O   1 
ATOM   10937 C  CB  . GLU B 1 613 ? 207.224 241.020 185.361 1.00 93.24  ? 613 GLU B CB  1 
ATOM   10938 C  CG  . GLU B 1 613 ? 207.538 241.365 186.827 1.00 94.00  ? 613 GLU B CG  1 
ATOM   10939 C  CD  . GLU B 1 613 ? 208.933 240.987 187.284 1.00 95.03  ? 613 GLU B CD  1 
ATOM   10940 O  OE1 . GLU B 1 613 ? 209.535 241.767 188.050 1.00 95.62  ? 613 GLU B OE1 1 
ATOM   10941 O  OE2 . GLU B 1 613 ? 209.424 239.912 186.880 1.00 95.38  ? 613 GLU B OE2 1 
ATOM   10942 N  N   . ASN B 1 614 ? 209.103 243.647 184.968 1.00 80.97  ? 614 ASN B N   1 
ATOM   10943 C  CA  . ASN B 1 614 ? 209.199 245.097 184.926 1.00 82.30  ? 614 ASN B CA  1 
ATOM   10944 C  C   . ASN B 1 614 ? 209.572 245.568 183.531 1.00 83.53  ? 614 ASN B C   1 
ATOM   10945 O  O   . ASN B 1 614 ? 208.921 246.456 182.967 1.00 87.64  ? 614 ASN B O   1 
ATOM   10946 C  CB  . ASN B 1 614 ? 210.218 245.579 185.955 1.00 84.05  ? 614 ASN B CB  1 
ATOM   10947 C  CG  . ASN B 1 614 ? 209.861 245.158 187.362 1.00 86.30  ? 614 ASN B CG  1 
ATOM   10948 O  OD1 . ASN B 1 614 ? 209.181 245.884 188.086 1.00 84.13  ? 614 ASN B OD1 1 
ATOM   10949 N  ND2 . ASN B 1 614 ? 210.321 243.980 187.761 1.00 90.84  ? 614 ASN B ND2 1 
ATOM   10950 N  N   . ILE B 1 615 ? 210.614 244.967 182.952 1.00 78.69  ? 615 ILE B N   1 
ATOM   10951 C  CA  . ILE B 1 615 ? 211.020 245.334 181.602 1.00 77.80  ? 615 ILE B CA  1 
ATOM   10952 C  C   . ILE B 1 615 ? 209.891 245.054 180.628 1.00 81.75  ? 615 ILE B C   1 
ATOM   10953 O  O   . ILE B 1 615 ? 209.643 245.834 179.705 1.00 83.01  ? 615 ILE B O   1 
ATOM   10954 C  CB  . ILE B 1 615 ? 212.312 244.599 181.206 1.00 76.88  ? 615 ILE B CB  1 
ATOM   10955 C  CG1 . ILE B 1 615 ? 213.399 244.843 182.244 1.00 77.99  ? 615 ILE B CG1 1 
ATOM   10956 C  CG2 . ILE B 1 615 ? 212.799 245.065 179.858 1.00 75.12  ? 615 ILE B CG2 1 
ATOM   10957 C  CD1 . ILE B 1 615 ? 214.703 244.162 181.915 1.00 74.06  ? 615 ILE B CD1 1 
ATOM   10958 N  N   . GLY B 1 616 ? 209.173 243.949 180.831 1.00 85.17  ? 616 GLY B N   1 
ATOM   10959 C  CA  . GLY B 1 616 ? 208.093 243.614 179.915 1.00 89.68  ? 616 GLY B CA  1 
ATOM   10960 C  C   . GLY B 1 616 ? 206.990 244.656 179.903 1.00 90.08  ? 616 GLY B C   1 
ATOM   10961 O  O   . GLY B 1 616 ? 206.617 245.179 178.844 1.00 90.70  ? 616 GLY B O   1 
ATOM   10962 N  N   . ARG B 1 617 ? 206.460 244.986 181.083 1.00 84.21  ? 617 ARG B N   1 
ATOM   10963 C  CA  . ARG B 1 617 ? 205.353 245.931 181.102 1.00 80.00  ? 617 ARG B CA  1 
ATOM   10964 C  C   . ARG B 1 617 ? 205.812 247.329 180.729 1.00 75.04  ? 617 ARG B C   1 
ATOM   10965 O  O   . ARG B 1 617 ? 205.065 248.061 180.072 1.00 77.99  ? 617 ARG B O   1 
ATOM   10966 C  CB  . ARG B 1 617 ? 204.635 245.932 182.452 1.00 82.42  ? 617 ARG B CB  1 
ATOM   10967 C  CG  . ARG B 1 617 ? 205.092 246.960 183.460 1.00 79.90  ? 617 ARG B CG  1 
ATOM   10968 C  CD  . ARG B 1 617 ? 204.463 246.664 184.817 1.00 82.39  ? 617 ARG B CD  1 
ATOM   10969 N  NE  . ARG B 1 617 ? 205.130 245.617 185.581 1.00 86.30  ? 617 ARG B NE  1 
ATOM   10970 C  CZ  . ARG B 1 617 ? 206.228 245.794 186.301 1.00 86.87  ? 617 ARG B CZ  1 
ATOM   10971 N  NH1 . ARG B 1 617 ? 206.834 246.969 186.362 1.00 84.88  ? 617 ARG B NH1 1 
ATOM   10972 N  NH2 . ARG B 1 617 ? 206.727 244.769 186.985 1.00 86.92  ? 617 ARG B NH2 1 
ATOM   10973 N  N   . TRP B 1 618 ? 207.038 247.710 181.089 1.00 75.02  ? 618 TRP B N   1 
ATOM   10974 C  CA  . TRP B 1 618 ? 207.532 249.009 180.658 1.00 77.62  ? 618 TRP B CA  1 
ATOM   10975 C  C   . TRP B 1 618 ? 207.675 249.069 179.145 1.00 80.94  ? 618 TRP B C   1 
ATOM   10976 O  O   . TRP B 1 618 ? 207.324 250.078 178.527 1.00 81.78  ? 618 TRP B O   1 
ATOM   10977 C  CB  . TRP B 1 618 ? 208.861 249.327 181.329 1.00 75.90  ? 618 TRP B CB  1 
ATOM   10978 C  CG  . TRP B 1 618 ? 209.441 250.584 180.813 1.00 77.56  ? 618 TRP B CG  1 
ATOM   10979 C  CD1 . TRP B 1 618 ? 209.244 251.833 181.308 1.00 83.44  ? 618 TRP B CD1 1 
ATOM   10980 C  CD2 . TRP B 1 618 ? 210.306 250.729 179.683 1.00 76.86  ? 618 TRP B CD2 1 
ATOM   10981 N  NE1 . TRP B 1 618 ? 209.937 252.750 180.560 1.00 83.08  ? 618 TRP B NE1 1 
ATOM   10982 C  CE2 . TRP B 1 618 ? 210.596 252.094 179.555 1.00 75.76  ? 618 TRP B CE2 1 
ATOM   10983 C  CE3 . TRP B 1 618 ? 210.863 249.836 178.769 1.00 77.74  ? 618 TRP B CE3 1 
ATOM   10984 C  CZ2 . TRP B 1 618 ? 211.417 252.587 178.555 1.00 66.92  ? 618 TRP B CZ2 1 
ATOM   10985 C  CZ3 . TRP B 1 618 ? 211.677 250.329 177.778 1.00 71.28  ? 618 TRP B CZ3 1 
ATOM   10986 C  CH2 . TRP B 1 618 ? 211.946 251.692 177.678 1.00 63.72  ? 618 TRP B CH2 1 
ATOM   10987 N  N   . VAL B 1 619 ? 208.187 248.001 178.527 1.00 79.18  ? 619 VAL B N   1 
ATOM   10988 C  CA  . VAL B 1 619 ? 208.362 247.990 177.078 1.00 76.72  ? 619 VAL B CA  1 
ATOM   10989 C  C   . VAL B 1 619 ? 207.014 248.118 176.385 1.00 84.44  ? 619 VAL B C   1 
ATOM   10990 O  O   . VAL B 1 619 ? 206.842 248.922 175.459 1.00 85.11  ? 619 VAL B O   1 
ATOM   10991 C  CB  . VAL B 1 619 ? 209.102 246.717 176.637 1.00 73.09  ? 619 VAL B CB  1 
ATOM   10992 C  CG1 . VAL B 1 619 ? 208.817 246.430 175.186 1.00 71.06  ? 619 VAL B CG1 1 
ATOM   10993 C  CG2 . VAL B 1 619 ? 210.591 246.866 176.858 1.00 72.35  ? 619 VAL B CG2 1 
ATOM   10994 N  N   . ILE B 1 620 ? 206.024 247.352 176.851 1.00 89.64  ? 620 ILE B N   1 
ATOM   10995 C  CA  . ILE B 1 620 ? 204.699 247.407 176.238 1.00 92.16  ? 620 ILE B CA  1 
ATOM   10996 C  C   . ILE B 1 620 ? 204.094 248.798 176.393 1.00 87.10  ? 620 ILE B C   1 
ATOM   10997 O  O   . ILE B 1 620 ? 203.600 249.396 175.426 1.00 81.24  ? 620 ILE B O   1 
ATOM   10998 C  CB  . ILE B 1 620 ? 203.786 246.327 176.844 1.00 94.85  ? 620 ILE B CB  1 
ATOM   10999 C  CG1 . ILE B 1 620 ? 204.303 244.933 176.490 1.00 93.16  ? 620 ILE B CG1 1 
ATOM   11000 C  CG2 . ILE B 1 620 ? 202.357 246.501 176.355 1.00 96.08  ? 620 ILE B CG2 1 
ATOM   11001 C  CD1 . ILE B 1 620 ? 203.722 243.833 177.348 1.00 98.63  ? 620 ILE B CD1 1 
ATOM   11002 N  N   . ALA B 1 621 ? 204.122 249.333 177.617 1.00 83.86  ? 621 ALA B N   1 
ATOM   11003 C  CA  . ALA B 1 621 ? 203.500 250.624 177.871 1.00 76.89  ? 621 ALA B CA  1 
ATOM   11004 C  C   . ALA B 1 621 ? 204.171 251.726 177.070 1.00 78.83  ? 621 ALA B C   1 
ATOM   11005 O  O   . ALA B 1 621 ? 203.493 252.579 176.484 1.00 87.12  ? 621 ALA B O   1 
ATOM   11006 C  CB  . ALA B 1 621 ? 203.547 250.940 179.363 1.00 71.35  ? 621 ALA B CB  1 
ATOM   11007 N  N   . GLU B 1 622 ? 205.501 251.724 177.027 1.00 76.44  ? 622 GLU B N   1 
ATOM   11008 C  CA  . GLU B 1 622 ? 206.203 252.758 176.285 1.00 81.34  ? 622 GLU B CA  1 
ATOM   11009 C  C   . GLU B 1 622 ? 205.935 252.642 174.795 1.00 83.30  ? 622 GLU B C   1 
ATOM   11010 O  O   . GLU B 1 622 ? 205.816 253.659 174.106 1.00 86.84  ? 622 GLU B O   1 
ATOM   11011 C  CB  . GLU B 1 622 ? 207.699 252.688 176.572 1.00 82.50  ? 622 GLU B CB  1 
ATOM   11012 C  CG  . GLU B 1 622 ? 208.184 253.720 177.576 1.00 85.54  ? 622 GLU B CG  1 
ATOM   11013 C  CD  . GLU B 1 622 ? 207.932 255.142 177.116 1.00 91.15  ? 622 GLU B CD  1 
ATOM   11014 O  OE1 . GLU B 1 622 ? 208.488 255.535 176.069 1.00 90.45  ? 622 GLU B OE1 1 
ATOM   11015 O  OE2 . GLU B 1 622 ? 207.182 255.867 177.800 1.00 91.91  ? 622 GLU B OE2 1 
ATOM   11016 N  N   . ALA B 1 623 ? 205.830 251.418 174.273 1.00 78.68  ? 623 ALA B N   1 
ATOM   11017 C  CA  . ALA B 1 623 ? 205.521 251.266 172.857 1.00 76.05  ? 623 ALA B CA  1 
ATOM   11018 C  C   . ALA B 1 623 ? 204.136 251.807 172.537 1.00 83.41  ? 623 ALA B C   1 
ATOM   11019 O  O   . ALA B 1 623 ? 203.946 252.488 171.522 1.00 83.01  ? 623 ALA B O   1 
ATOM   11020 C  CB  . ALA B 1 623 ? 205.634 249.799 172.451 1.00 75.73  ? 623 ALA B CB  1 
ATOM   11021 N  N   . CYS B 1 624 ? 203.154 251.519 173.397 1.00 87.71  ? 624 CYS B N   1 
ATOM   11022 C  CA  . CYS B 1 624 ? 201.804 252.038 173.179 1.00 91.44  ? 624 CYS B CA  1 
ATOM   11023 C  C   . CYS B 1 624 ? 201.790 253.564 173.216 1.00 91.00  ? 624 CYS B C   1 
ATOM   11024 O  O   . CYS B 1 624 ? 201.214 254.224 172.336 1.00 89.17  ? 624 CYS B O   1 
ATOM   11025 C  CB  . CYS B 1 624 ? 200.851 251.468 174.231 1.00 88.63  ? 624 CYS B CB  1 
ATOM   11026 S  SG  . CYS B 1 624 ? 200.225 249.816 173.878 1.00 94.36  ? 624 CYS B SG  1 
ATOM   11027 N  N   . ARG B 1 625 ? 202.444 254.140 174.226 1.00 87.04  ? 625 ARG B N   1 
ATOM   11028 C  CA  . ARG B 1 625 ? 202.543 255.588 174.320 1.00 81.73  ? 625 ARG B CA  1 
ATOM   11029 C  C   . ARG B 1 625 ? 203.207 256.171 173.084 1.00 79.34  ? 625 ARG B C   1 
ATOM   11030 O  O   . ARG B 1 625 ? 202.785 257.215 172.578 1.00 83.06  ? 625 ARG B O   1 
ATOM   11031 C  CB  . ARG B 1 625 ? 203.327 255.960 175.576 1.00 85.45  ? 625 ARG B CB  1 
ATOM   11032 C  CG  . ARG B 1 625 ? 202.896 257.234 176.258 1.00 92.27  ? 625 ARG B CG  1 
ATOM   11033 C  CD  . ARG B 1 625 ? 203.640 258.424 175.704 1.00 93.92  ? 625 ARG B CD  1 
ATOM   11034 N  NE  . ARG B 1 625 ? 205.044 258.389 176.087 1.00 92.75  ? 625 ARG B NE  1 
ATOM   11035 C  CZ  . ARG B 1 625 ? 205.971 259.202 175.602 1.00 94.67  ? 625 ARG B CZ  1 
ATOM   11036 N  NH1 . ARG B 1 625 ? 205.673 260.139 174.717 1.00 93.59  ? 625 ARG B NH1 1 
ATOM   11037 N  NH2 . ARG B 1 625 ? 207.228 259.073 176.016 1.00 96.38  ? 625 ARG B NH2 1 
ATOM   11038 N  N   . GLN B 1 626 ? 204.258 255.519 172.592 1.00 76.97  ? 626 GLN B N   1 
ATOM   11039 C  CA  . GLN B 1 626 ? 204.992 256.046 171.451 1.00 77.22  ? 626 GLN B CA  1 
ATOM   11040 C  C   . GLN B 1 626 ? 204.149 256.007 170.193 1.00 78.11  ? 626 GLN B C   1 
ATOM   11041 O  O   . GLN B 1 626 ? 204.215 256.923 169.364 1.00 79.31  ? 626 GLN B O   1 
ATOM   11042 C  CB  . GLN B 1 626 ? 206.284 255.263 171.247 1.00 78.39  ? 626 GLN B CB  1 
ATOM   11043 C  CG  . GLN B 1 626 ? 207.182 255.857 170.189 1.00 75.32  ? 626 GLN B CG  1 
ATOM   11044 C  CD  . GLN B 1 626 ? 207.419 257.328 170.398 1.00 74.08  ? 626 GLN B CD  1 
ATOM   11045 O  OE1 . GLN B 1 626 ? 207.746 257.768 171.498 1.00 72.31  ? 626 GLN B OE1 1 
ATOM   11046 N  NE2 . GLN B 1 626 ? 207.246 258.105 169.340 1.00 76.38  ? 626 GLN B NE2 1 
ATOM   11047 N  N   . LEU B 1 627 ? 203.369 254.944 170.020 1.00 80.27  ? 627 LEU B N   1 
ATOM   11048 C  CA  . LEU B 1 627 ? 202.448 254.906 168.893 1.00 87.04  ? 627 LEU B CA  1 
ATOM   11049 C  C   . LEU B 1 627 ? 201.441 256.041 168.986 1.00 85.05  ? 627 LEU B C   1 
ATOM   11050 O  O   . LEU B 1 627 ? 201.123 256.684 167.980 1.00 82.17  ? 627 LEU B O   1 
ATOM   11051 C  CB  . LEU B 1 627 ? 201.745 253.554 168.826 1.00 87.17  ? 627 LEU B CB  1 
ATOM   11052 C  CG  . LEU B 1 627 ? 202.510 252.487 168.046 1.00 78.56  ? 627 LEU B CG  1 
ATOM   11053 C  CD1 . LEU B 1 627 ? 201.890 251.116 168.253 1.00 76.42  ? 627 LEU B CD1 1 
ATOM   11054 C  CD2 . LEU B 1 627 ? 202.550 252.848 166.577 1.00 75.08  ? 627 LEU B CD2 1 
ATOM   11055 N  N   . ALA B 1 628 ? 200.937 256.312 170.190 1.00 83.95  ? 628 ALA B N   1 
ATOM   11056 C  CA  . ALA B 1 628 ? 200.023 257.439 170.341 1.00 82.87  ? 628 ALA B CA  1 
ATOM   11057 C  C   . ALA B 1 628 ? 200.706 258.749 169.973 1.00 77.93  ? 628 ALA B C   1 
ATOM   11058 O  O   . ALA B 1 628 ? 200.133 259.583 169.263 1.00 74.32  ? 628 ALA B O   1 
ATOM   11059 C  CB  . ALA B 1 628 ? 199.485 257.493 171.768 1.00 89.95  ? 628 ALA B CB  1 
ATOM   11060 N  N   . GLU B 1 629 ? 201.941 258.937 170.436 1.00 80.89  ? 629 GLU B N   1 
ATOM   11061 C  CA  . GLU B 1 629 ? 202.660 260.183 170.183 1.00 85.43  ? 629 GLU B CA  1 
ATOM   11062 C  C   . GLU B 1 629 ? 202.896 260.391 168.693 1.00 85.57  ? 629 GLU B C   1 
ATOM   11063 O  O   . GLU B 1 629 ? 202.700 261.495 168.173 1.00 86.87  ? 629 GLU B O   1 
ATOM   11064 C  CB  . GLU B 1 629 ? 203.987 260.180 170.946 1.00 86.53  ? 629 GLU B CB  1 
ATOM   11065 C  CG  . GLU B 1 629 ? 204.940 261.307 170.573 1.00 88.05  ? 629 GLU B CG  1 
ATOM   11066 C  CD  . GLU B 1 629 ? 206.304 261.161 171.227 1.00 90.10  ? 629 GLU B CD  1 
ATOM   11067 O  OE1 . GLU B 1 629 ? 206.372 261.159 172.473 1.00 91.05  ? 629 GLU B OE1 1 
ATOM   11068 O  OE2 . GLU B 1 629 ? 207.308 261.049 170.496 1.00 89.37  ? 629 GLU B OE2 1 
ATOM   11069 N  N   . TRP B 1 630 ? 203.313 259.337 167.989 1.00 83.36  ? 630 TRP B N   1 
ATOM   11070 C  CA  . TRP B 1 630 ? 203.418 259.400 166.535 1.00 80.46  ? 630 TRP B CA  1 
ATOM   11071 C  C   . TRP B 1 630 ? 202.063 259.615 165.874 1.00 79.82  ? 630 TRP B C   1 
ATOM   11072 O  O   . TRP B 1 630 ? 201.995 260.174 164.777 1.00 76.42  ? 630 TRP B O   1 
ATOM   11073 C  CB  . TRP B 1 630 ? 204.073 258.124 166.016 1.00 77.98  ? 630 TRP B CB  1 
ATOM   11074 C  CG  . TRP B 1 630 ? 205.556 258.207 165.871 1.00 75.87  ? 630 TRP B CG  1 
ATOM   11075 C  CD1 . TRP B 1 630 ? 206.292 259.328 165.647 1.00 74.63  ? 630 TRP B CD1 1 
ATOM   11076 C  CD2 . TRP B 1 630 ? 206.489 257.129 165.979 1.00 69.97  ? 630 TRP B CD2 1 
ATOM   11077 N  NE1 . TRP B 1 630 ? 207.626 259.010 165.571 1.00 70.49  ? 630 TRP B NE1 1 
ATOM   11078 C  CE2 . TRP B 1 630 ? 207.770 257.666 165.776 1.00 68.03  ? 630 TRP B CE2 1 
ATOM   11079 C  CE3 . TRP B 1 630 ? 206.364 255.761 166.211 1.00 67.19  ? 630 TRP B CE3 1 
ATOM   11080 C  CZ2 . TRP B 1 630 ? 208.913 256.888 165.806 1.00 66.22  ? 630 TRP B CZ2 1 
ATOM   11081 C  CZ3 . TRP B 1 630 ? 207.498 254.992 166.236 1.00 64.65  ? 630 TRP B CZ3 1 
ATOM   11082 C  CH2 . TRP B 1 630 ? 208.756 255.554 166.036 1.00 66.07  ? 630 TRP B CH2 1 
ATOM   11083 N  N   . ARG B 1 631 ? 200.978 259.180 166.520 1.00 79.89  ? 631 ARG B N   1 
ATOM   11084 C  CA  . ARG B 1 631 ? 199.657 259.302 165.915 1.00 79.58  ? 631 ARG B CA  1 
ATOM   11085 C  C   . ARG B 1 631 ? 199.224 260.753 165.783 1.00 79.94  ? 631 ARG B C   1 
ATOM   11086 O  O   . ARG B 1 631 ? 198.461 261.093 164.871 1.00 78.96  ? 631 ARG B O   1 
ATOM   11087 C  CB  . ARG B 1 631 ? 198.633 258.512 166.732 1.00 81.99  ? 631 ARG B CB  1 
ATOM   11088 C  CG  . ARG B 1 631 ? 197.235 258.500 166.133 1.00 84.56  ? 631 ARG B CG  1 
ATOM   11089 C  CD  . ARG B 1 631 ? 196.329 257.478 166.800 1.00 86.38  ? 631 ARG B CD  1 
ATOM   11090 N  NE  . ARG B 1 631 ? 195.896 257.886 168.130 1.00 89.03  ? 631 ARG B NE  1 
ATOM   11091 C  CZ  . ARG B 1 631 ? 195.357 257.065 169.021 1.00 93.31  ? 631 ARG B CZ  1 
ATOM   11092 N  NH1 . ARG B 1 631 ? 195.175 255.782 168.757 1.00 94.02  ? 631 ARG B NH1 1 
ATOM   11093 N  NH2 . ARG B 1 631 ? 194.990 257.543 170.206 1.00 95.86  ? 631 ARG B NH2 1 
ATOM   11094 N  N   . SER B 1 632 ? 199.695 261.623 166.678 1.00 78.68  ? 632 SER B N   1 
ATOM   11095 C  CA  . SER B 1 632 ? 199.274 263.018 166.655 1.00 71.87  ? 632 SER B CA  1 
ATOM   11096 C  C   . SER B 1 632 ? 199.737 263.752 165.402 1.00 72.23  ? 632 SER B C   1 
ATOM   11097 O  O   . SER B 1 632 ? 199.032 264.652 164.934 1.00 72.17  ? 632 SER B O   1 
ATOM   11098 C  CB  . SER B 1 632 ? 199.778 263.727 167.909 1.00 66.44  ? 632 SER B CB  1 
ATOM   11099 O  OG  . SER B 1 632 ? 201.189 263.708 167.965 1.00 68.67  ? 632 SER B OG  1 
ATOM   11100 N  N   . GLN B 1 633 ? 200.893 263.395 164.844 1.00 72.93  ? 633 GLN B N   1 
ATOM   11101 C  CA  . GLN B 1 633 ? 201.354 263.974 163.586 1.00 71.98  ? 633 GLN B CA  1 
ATOM   11102 C  C   . GLN B 1 633 ? 201.009 263.116 162.375 1.00 73.59  ? 633 GLN B C   1 
ATOM   11103 O  O   . GLN B 1 633 ? 200.435 263.619 161.406 1.00 68.20  ? 633 GLN B O   1 
ATOM   11104 C  CB  . GLN B 1 633 ? 202.869 264.220 163.621 1.00 70.38  ? 633 GLN B CB  1 
ATOM   11105 C  CG  . GLN B 1 633 ? 203.388 265.166 164.709 1.00 71.58  ? 633 GLN B CG  1 
ATOM   11106 C  CD  . GLN B 1 633 ? 203.225 264.642 166.123 1.00 75.13  ? 633 GLN B CD  1 
ATOM   11107 O  OE1 . GLN B 1 633 ? 202.711 263.547 166.341 1.00 72.83  ? 633 GLN B OE1 1 
ATOM   11108 N  NE2 . GLN B 1 633 ? 203.670 265.428 167.095 1.00 77.49  ? 633 GLN B NE2 1 
ATOM   11109 N  N   . ASN B 1 634 ? 201.356 261.831 162.402 1.00 77.56  ? 634 ASN B N   1 
ATOM   11110 C  CA  . ASN B 1 634 ? 201.069 260.935 161.291 1.00 81.57  ? 634 ASN B CA  1 
ATOM   11111 C  C   . ASN B 1 634 ? 200.534 259.617 161.831 1.00 87.54  ? 634 ASN B C   1 
ATOM   11112 O  O   . ASN B 1 634 ? 201.207 258.950 162.621 1.00 85.92  ? 634 ASN B O   1 
ATOM   11113 C  CB  . ASN B 1 634 ? 202.319 260.677 160.447 1.00 79.23  ? 634 ASN B CB  1 
ATOM   11114 C  CG  . ASN B 1 634 ? 203.527 260.336 161.289 1.00 78.96  ? 634 ASN B CG  1 
ATOM   11115 O  OD1 . ASN B 1 634 ? 203.469 260.360 162.515 1.00 75.00  ? 634 ASN B OD1 1 
ATOM   11116 N  ND2 . ASN B 1 634 ? 204.632 260.010 160.632 1.00 83.58  ? 634 ASN B ND2 1 
ATOM   11117 N  N   . ILE B 1 635 ? 199.332 259.232 161.389 1.00 91.91  ? 635 ILE B N   1 
ATOM   11118 C  CA  . ILE B 1 635 ? 198.747 257.961 161.807 1.00 92.76  ? 635 ILE B CA  1 
ATOM   11119 C  C   . ILE B 1 635 ? 199.135 256.811 160.889 1.00 92.83  ? 635 ILE B C   1 
ATOM   11120 O  O   . ILE B 1 635 ? 198.756 255.662 161.152 1.00 90.18  ? 635 ILE B O   1 
ATOM   11121 C  CB  . ILE B 1 635 ? 197.208 258.062 161.880 1.00 91.49  ? 635 ILE B CB  1 
ATOM   11122 C  CG1 . ILE B 1 635 ? 196.597 257.947 160.481 1.00 90.19  ? 635 ILE B CG1 1 
ATOM   11123 C  CG2 . ILE B 1 635 ? 196.792 259.367 162.538 1.00 86.91  ? 635 ILE B CG2 1 
ATOM   11124 C  CD1 . ILE B 1 635 ? 195.094 258.137 160.450 1.00 83.07  ? 635 ILE B CD1 1 
ATOM   11125 N  N   . HIS B 1 636 ? 199.906 257.076 159.838 1.00 92.72  ? 636 HIS B N   1 
ATOM   11126 C  CA  . HIS B 1 636 ? 200.163 256.081 158.808 1.00 95.46  ? 636 HIS B CA  1 
ATOM   11127 C  C   . HIS B 1 636 ? 201.097 254.968 159.266 1.00 90.62  ? 636 HIS B C   1 
ATOM   11128 O  O   . HIS B 1 636 ? 201.422 254.092 158.459 1.00 92.74  ? 636 HIS B O   1 
ATOM   11129 C  CB  . HIS B 1 636 ? 200.741 256.770 157.569 1.00 98.71  ? 636 HIS B CB  1 
ATOM   11130 C  CG  . HIS B 1 636 ? 200.593 255.978 156.308 1.00 102.00 ? 636 HIS B CG  1 
ATOM   11131 N  ND1 . HIS B 1 636 ? 201.565 255.113 155.853 1.00 99.46  ? 636 HIS B ND1 1 
ATOM   11132 C  CD2 . HIS B 1 636 ? 199.586 255.921 155.404 1.00 99.89  ? 636 HIS B CD2 1 
ATOM   11133 C  CE1 . HIS B 1 636 ? 201.164 254.558 154.723 1.00 94.77  ? 636 HIS B CE1 1 
ATOM   11134 N  NE2 . HIS B 1 636 ? 199.967 255.030 154.429 1.00 95.00  ? 636 HIS B NE2 1 
ATOM   11135 N  N   . ILE B 1 637 ? 201.538 254.980 160.521 1.00 83.24  ? 637 ILE B N   1 
ATOM   11136 C  CA  . ILE B 1 637 ? 202.476 253.978 161.023 1.00 81.75  ? 637 ILE B CA  1 
ATOM   11137 C  C   . ILE B 1 637 ? 201.812 252.602 160.985 1.00 81.65  ? 637 ILE B C   1 
ATOM   11138 O  O   . ILE B 1 637 ? 200.875 252.345 161.754 1.00 83.03  ? 637 ILE B O   1 
ATOM   11139 C  CB  . ILE B 1 637 ? 202.967 254.352 162.430 1.00 82.17  ? 637 ILE B CB  1 
ATOM   11140 C  CG1 . ILE B 1 637 ? 203.720 253.185 163.061 1.00 79.01  ? 637 ILE B CG1 1 
ATOM   11141 C  CG2 . ILE B 1 637 ? 201.809 254.829 163.298 1.00 86.36  ? 637 ILE B CG2 1 
ATOM   11142 C  CD1 . ILE B 1 637 ? 205.041 252.917 162.399 1.00 73.66  ? 637 ILE B CD1 1 
ATOM   11143 N  N   . PRO B 1 638 ? 202.251 251.691 160.100 1.00 71.96  ? 638 PRO B N   1 
ATOM   11144 C  CA  . PRO B 1 638 ? 201.473 250.468 159.853 1.00 62.54  ? 638 PRO B CA  1 
ATOM   11145 C  C   . PRO B 1 638 ? 201.452 249.460 160.994 1.00 62.93  ? 638 PRO B C   1 
ATOM   11146 O  O   . PRO B 1 638 ? 200.375 249.067 161.447 1.00 63.21  ? 638 PRO B O   1 
ATOM   11147 C  CB  . PRO B 1 638 ? 202.150 249.877 158.611 1.00 60.37  ? 638 PRO B CB  1 
ATOM   11148 C  CG  . PRO B 1 638 ? 203.505 250.416 158.615 1.00 61.80  ? 638 PRO B CG  1 
ATOM   11149 C  CD  . PRO B 1 638 ? 203.462 251.757 159.270 1.00 70.71  ? 638 PRO B CD  1 
ATOM   11150 N  N   . ALA B 1 639 ? 202.616 249.034 161.475 1.00 64.65  ? 639 ALA B N   1 
ATOM   11151 C  CA  . ALA B 1 639 ? 202.654 247.972 162.470 1.00 62.68  ? 639 ALA B CA  1 
ATOM   11152 C  C   . ALA B 1 639 ? 203.936 248.064 163.281 1.00 58.57  ? 639 ALA B C   1 
ATOM   11153 O  O   . ALA B 1 639 ? 204.981 248.482 162.780 1.00 61.40  ? 639 ALA B O   1 
ATOM   11154 C  CB  . ALA B 1 639 ? 202.541 246.595 161.816 1.00 59.86  ? 639 ALA B CB  1 
ATOM   11155 N  N   . LEU B 1 640 ? 203.844 247.654 164.539 1.00 51.26  ? 640 LEU B N   1 
ATOM   11156 C  CA  . LEU B 1 640 ? 204.944 247.714 165.485 1.00 47.22  ? 640 LEU B CA  1 
ATOM   11157 C  C   . LEU B 1 640 ? 205.000 246.383 166.213 1.00 51.30  ? 640 LEU B C   1 
ATOM   11158 O  O   . LEU B 1 640 ? 203.999 245.949 166.787 1.00 58.45  ? 640 LEU B O   1 
ATOM   11159 C  CB  . LEU B 1 640 ? 204.736 248.868 166.467 1.00 54.33  ? 640 LEU B CB  1 
ATOM   11160 C  CG  . LEU B 1 640 ? 205.696 249.092 167.625 1.00 61.21  ? 640 LEU B CG  1 
ATOM   11161 C  CD1 . LEU B 1 640 ? 205.982 250.574 167.760 1.00 63.06  ? 640 LEU B CD1 1 
ATOM   11162 C  CD2 . LEU B 1 640 ? 205.102 248.550 168.908 1.00 62.58  ? 640 LEU B CD2 1 
ATOM   11163 N  N   . SER B 1 641 ? 206.157 245.732 166.187 1.00 52.39  ? 641 SER B N   1 
ATOM   11164 C  CA  . SER B 1 641 ? 206.268 244.353 166.636 1.00 54.29  ? 641 SER B CA  1 
ATOM   11165 C  C   . SER B 1 641 ? 207.216 244.253 167.819 1.00 50.70  ? 641 SER B C   1 
ATOM   11166 O  O   . SER B 1 641 ? 208.323 244.799 167.788 1.00 54.80  ? 641 SER B O   1 
ATOM   11167 C  CB  . SER B 1 641 ? 206.750 243.437 165.513 1.00 56.08  ? 641 SER B CB  1 
ATOM   11168 O  OG  . SER B 1 641 ? 208.148 243.266 165.583 1.00 57.17  ? 641 SER B OG  1 
ATOM   11169 N  N   . VAL B 1 642 ? 206.782 243.535 168.845 1.00 45.27  ? 642 VAL B N   1 
ATOM   11170 C  CA  . VAL B 1 642 ? 207.541 243.334 170.067 1.00 42.72  ? 642 VAL B CA  1 
ATOM   11171 C  C   . VAL B 1 642 ? 207.886 241.857 170.163 1.00 53.49  ? 642 VAL B C   1 
ATOM   11172 O  O   . VAL B 1 642 ? 207.005 240.993 170.033 1.00 61.99  ? 642 VAL B O   1 
ATOM   11173 C  CB  . VAL B 1 642 ? 206.740 243.801 171.290 1.00 40.52  ? 642 VAL B CB  1 
ATOM   11174 C  CG1 . VAL B 1 642 ? 207.604 243.765 172.528 1.00 53.28  ? 642 VAL B CG1 1 
ATOM   11175 C  CG2 . VAL B 1 642 ? 206.211 245.193 171.047 1.00 40.23  ? 642 VAL B CG2 1 
ATOM   11176 N  N   . ASN B 1 643 ? 209.167 241.565 170.364 1.00 53.33  ? 643 ASN B N   1 
ATOM   11177 C  CA  . ASN B 1 643 ? 209.659 240.191 170.359 1.00 58.77  ? 643 ASN B CA  1 
ATOM   11178 C  C   . ASN B 1 643 ? 209.645 239.746 171.812 1.00 60.68  ? 643 ASN B C   1 
ATOM   11179 O  O   . ASN B 1 643 ? 210.532 240.100 172.591 1.00 65.11  ? 643 ASN B O   1 
ATOM   11180 C  CB  . ASN B 1 643 ? 211.044 240.127 169.717 1.00 63.61  ? 643 ASN B CB  1 
ATOM   11181 C  CG  . ASN B 1 643 ? 211.839 238.861 170.064 1.00 71.44  ? 643 ASN B CG  1 
ATOM   11182 O  OD1 . ASN B 1 643 ? 211.475 238.062 170.925 1.00 74.75  ? 643 ASN B OD1 1 
ATOM   11183 N  ND2 . ASN B 1 643 ? 212.954 238.685 169.365 1.00 74.68  ? 643 ASN B ND2 1 
ATOM   11184 N  N   . LEU B 1 644 ? 208.634 238.971 172.183 1.00 57.08  ? 644 LEU B N   1 
ATOM   11185 C  CA  . LEU B 1 644 ? 208.492 238.557 173.568 1.00 61.51  ? 644 LEU B CA  1 
ATOM   11186 C  C   . LEU B 1 644 ? 209.315 237.328 173.912 1.00 67.34  ? 644 LEU B C   1 
ATOM   11187 O  O   . LEU B 1 644 ? 209.460 237.015 175.096 1.00 71.21  ? 644 LEU B O   1 
ATOM   11188 C  CB  . LEU B 1 644 ? 207.024 238.295 173.903 1.00 62.28  ? 644 LEU B CB  1 
ATOM   11189 C  CG  . LEU B 1 644 ? 206.120 239.495 174.188 1.00 63.02  ? 644 LEU B CG  1 
ATOM   11190 C  CD1 . LEU B 1 644 ? 206.583 240.221 175.437 1.00 70.20  ? 644 LEU B CD1 1 
ATOM   11191 C  CD2 . LEU B 1 644 ? 206.022 240.449 173.018 1.00 55.42  ? 644 LEU B CD2 1 
ATOM   11192 N  N   . SER B 1 645 ? 209.844 236.618 172.921 1.00 68.28  ? 645 SER B N   1 
ATOM   11193 C  CA  . SER B 1 645 ? 210.696 235.475 173.222 1.00 71.63  ? 645 SER B CA  1 
ATOM   11194 C  C   . SER B 1 645 ? 212.057 235.930 173.729 1.00 76.32  ? 645 SER B C   1 
ATOM   11195 O  O   . SER B 1 645 ? 212.568 235.404 174.724 1.00 79.03  ? 645 SER B O   1 
ATOM   11196 C  CB  . SER B 1 645 ? 210.847 234.590 171.986 1.00 74.11  ? 645 SER B CB  1 
ATOM   11197 O  OG  . SER B 1 645 ? 211.854 233.613 172.182 1.00 78.66  ? 645 SER B OG  1 
ATOM   11198 N  N   . ALA B 1 646 ? 212.656 236.920 173.060 1.00 77.51  ? 646 ALA B N   1 
ATOM   11199 C  CA  . ALA B 1 646 ? 213.949 237.445 173.486 1.00 77.62  ? 646 ALA B CA  1 
ATOM   11200 C  C   . ALA B 1 646 ? 213.857 238.217 174.790 1.00 77.84  ? 646 ALA B C   1 
ATOM   11201 O  O   . ALA B 1 646 ? 214.887 238.473 175.419 1.00 77.59  ? 646 ALA B O   1 
ATOM   11202 C  CB  . ALA B 1 646 ? 214.540 238.343 172.400 1.00 71.99  ? 646 ALA B CB  1 
ATOM   11203 N  N   . LEU B 1 647 ? 212.655 238.597 175.202 1.00 78.88  ? 647 LEU B N   1 
ATOM   11204 C  CA  . LEU B 1 647 ? 212.438 239.300 176.455 1.00 80.06  ? 647 LEU B CA  1 
ATOM   11205 C  C   . LEU B 1 647 ? 212.098 238.360 177.603 1.00 77.09  ? 647 LEU B C   1 
ATOM   11206 O  O   . LEU B 1 647 ? 211.825 238.834 178.710 1.00 77.60  ? 647 LEU B O   1 
ATOM   11207 C  CB  . LEU B 1 647 ? 211.327 240.343 176.284 1.00 81.63  ? 647 LEU B CB  1 
ATOM   11208 C  CG  . LEU B 1 647 ? 211.764 241.788 176.016 1.00 78.16  ? 647 LEU B CG  1 
ATOM   11209 C  CD1 . LEU B 1 647 ? 212.396 241.935 174.642 1.00 74.59  ? 647 LEU B CD1 1 
ATOM   11210 C  CD2 . LEU B 1 647 ? 210.588 242.732 176.161 1.00 75.21  ? 647 LEU B CD2 1 
ATOM   11211 N  N   . HIS B 1 648 ? 212.104 237.051 177.362 1.00 75.11  ? 648 HIS B N   1 
ATOM   11212 C  CA  . HIS B 1 648 ? 211.854 236.039 178.388 1.00 79.69  ? 648 HIS B CA  1 
ATOM   11213 C  C   . HIS B 1 648 ? 210.532 236.285 179.106 1.00 82.99  ? 648 HIS B C   1 
ATOM   11214 O  O   . HIS B 1 648 ? 210.422 236.143 180.324 1.00 84.74  ? 648 HIS B O   1 
ATOM   11215 C  CB  . HIS B 1 648 ? 213.006 235.971 179.388 1.00 81.49  ? 648 HIS B CB  1 
ATOM   11216 C  CG  . HIS B 1 648 ? 214.282 235.456 178.806 1.00 82.63  ? 648 HIS B CG  1 
ATOM   11217 N  ND1 . HIS B 1 648 ? 215.043 234.488 179.425 1.00 87.23  ? 648 HIS B ND1 1 
ATOM   11218 C  CD2 . HIS B 1 648 ? 214.936 235.775 177.665 1.00 81.10  ? 648 HIS B CD2 1 
ATOM   11219 C  CE1 . HIS B 1 648 ? 216.109 234.231 178.689 1.00 88.51  ? 648 HIS B CE1 1 
ATOM   11220 N  NE2 . HIS B 1 648 ? 216.068 234.999 177.616 1.00 87.09  ? 648 HIS B NE2 1 
ATOM   11221 N  N   . PHE B 1 649 ? 209.516 236.649 178.332 1.00 82.15  ? 649 PHE B N   1 
ATOM   11222 C  CA  . PHE B 1 649 ? 208.207 236.928 178.901 1.00 81.26  ? 649 PHE B CA  1 
ATOM   11223 C  C   . PHE B 1 649 ? 207.684 235.705 179.639 1.00 82.14  ? 649 PHE B C   1 
ATOM   11224 O  O   . PHE B 1 649 ? 207.782 234.579 179.148 1.00 81.97  ? 649 PHE B O   1 
ATOM   11225 C  CB  . PHE B 1 649 ? 207.237 237.334 177.800 1.00 79.90  ? 649 PHE B CB  1 
ATOM   11226 C  CG  . PHE B 1 649 ? 206.158 238.264 178.259 1.00 88.29  ? 649 PHE B CG  1 
ATOM   11227 C  CD1 . PHE B 1 649 ? 206.478 239.460 178.875 1.00 91.48  ? 649 PHE B CD1 1 
ATOM   11228 C  CD2 . PHE B 1 649 ? 204.826 237.950 178.069 1.00 93.17  ? 649 PHE B CD2 1 
ATOM   11229 C  CE1 . PHE B 1 649 ? 205.488 240.323 179.293 1.00 95.80  ? 649 PHE B CE1 1 
ATOM   11230 C  CE2 . PHE B 1 649 ? 203.833 238.812 178.490 1.00 98.11  ? 649 PHE B CE2 1 
ATOM   11231 C  CZ  . PHE B 1 649 ? 204.167 239.998 179.103 1.00 99.43  ? 649 PHE B CZ  1 
ATOM   11232 N  N   . ARG B 1 650 ? 207.132 235.926 180.824 1.00 86.01  ? 650 ARG B N   1 
ATOM   11233 C  CA  . ARG B 1 650 ? 206.665 234.838 181.671 1.00 89.40  ? 650 ARG B CA  1 
ATOM   11234 C  C   . ARG B 1 650 ? 205.269 234.400 181.238 1.00 89.61  ? 650 ARG B C   1 
ATOM   11235 O  O   . ARG B 1 650 ? 204.793 234.724 180.148 1.00 88.71  ? 650 ARG B O   1 
ATOM   11236 C  CB  . ARG B 1 650 ? 206.701 235.252 183.138 1.00 94.74  ? 650 ARG B CB  1 
ATOM   11237 C  CG  . ARG B 1 650 ? 208.082 235.207 183.768 1.00 92.92  ? 650 ARG B CG  1 
ATOM   11238 C  CD  . ARG B 1 650 ? 208.670 233.808 183.709 1.00 95.16  ? 650 ARG B CD  1 
ATOM   11239 N  NE  . ARG B 1 650 ? 209.598 233.649 182.595 1.00 95.37  ? 650 ARG B NE  1 
ATOM   11240 C  CZ  . ARG B 1 650 ? 210.267 232.536 182.330 1.00 95.98  ? 650 ARG B CZ  1 
ATOM   11241 N  NH1 . ARG B 1 650 ? 210.136 231.454 183.080 1.00 96.72  ? 650 ARG B NH1 1 
ATOM   11242 N  NH2 . ARG B 1 650 ? 211.089 232.507 181.285 1.00 94.79  ? 650 ARG B NH2 1 
ATOM   11243 N  N   . SER B 1 651 ? 204.606 233.628 182.097 1.00 92.91  ? 651 SER B N   1 
ATOM   11244 C  CA  . SER B 1 651 ? 203.303 233.054 181.780 1.00 102.23 ? 651 SER B CA  1 
ATOM   11245 C  C   . SER B 1 651 ? 202.151 233.960 182.207 1.00 107.20 ? 651 SER B C   1 
ATOM   11246 O  O   . SER B 1 651 ? 201.357 234.400 181.371 1.00 108.80 ? 651 SER B O   1 
ATOM   11247 C  CB  . SER B 1 651 ? 203.172 231.682 182.447 1.00 103.44 ? 651 SER B CB  1 
ATOM   11248 O  OG  . SER B 1 651 ? 203.535 231.753 183.814 1.00 99.07  ? 651 SER B OG  1 
ATOM   11249 N  N   . ASN B 1 652 ? 202.059 234.256 183.504 1.00 107.51 ? 652 ASN B N   1 
ATOM   11250 C  CA  . ASN B 1 652 ? 200.903 234.969 184.040 1.00 109.25 ? 652 ASN B CA  1 
ATOM   11251 C  C   . ASN B 1 652 ? 200.836 236.429 183.610 1.00 108.09 ? 652 ASN B C   1 
ATOM   11252 O  O   . ASN B 1 652 ? 199.797 237.070 183.799 1.00 106.91 ? 652 ASN B O   1 
ATOM   11253 C  CB  . ASN B 1 652 ? 200.894 234.846 185.569 1.00 108.61 ? 652 ASN B CB  1 
ATOM   11254 C  CG  . ASN B 1 652 ? 201.975 235.687 186.254 1.00 110.53 ? 652 ASN B CG  1 
ATOM   11255 O  OD1 . ASN B 1 652 ? 202.557 236.604 185.675 1.00 109.07 ? 652 ASN B OD1 1 
ATOM   11256 N  ND2 . ASN B 1 652 ? 202.242 235.362 187.514 1.00 111.19 ? 652 ASN B ND2 1 
ATOM   11257 N  N   . GLN B 1 653 ? 201.918 236.968 183.051 1.00 106.76 ? 653 GLN B N   1 
ATOM   11258 C  CA  . GLN B 1 653 ? 201.961 238.395 182.759 1.00 107.88 ? 653 GLN B CA  1 
ATOM   11259 C  C   . GLN B 1 653 ? 200.950 238.785 181.690 1.00 110.05 ? 653 GLN B C   1 
ATOM   11260 O  O   . GLN B 1 653 ? 200.220 239.769 181.854 1.00 111.79 ? 653 GLN B O   1 
ATOM   11261 C  CB  . GLN B 1 653 ? 203.370 238.788 182.323 1.00 105.43 ? 653 GLN B CB  1 
ATOM   11262 C  CG  . GLN B 1 653 ? 204.398 238.762 183.435 1.00 102.71 ? 653 GLN B CG  1 
ATOM   11263 C  CD  . GLN B 1 653 ? 205.771 239.175 182.953 1.00 97.57  ? 653 GLN B CD  1 
ATOM   11264 O  OE1 . GLN B 1 653 ? 206.747 238.444 183.112 1.00 92.68  ? 653 GLN B OE1 1 
ATOM   11265 N  NE2 . GLN B 1 653 ? 205.852 240.356 182.356 1.00 97.45  ? 653 GLN B NE2 1 
ATOM   11266 N  N   . LEU B 1 654 ? 200.873 238.007 180.607 1.00 110.33 ? 654 LEU B N   1 
ATOM   11267 C  CA  . LEU B 1 654 ? 200.221 238.377 179.351 1.00 114.62 ? 654 LEU B CA  1 
ATOM   11268 C  C   . LEU B 1 654 ? 198.882 239.098 179.514 1.00 114.75 ? 654 LEU B C   1 
ATOM   11269 O  O   . LEU B 1 654 ? 198.755 240.243 179.056 1.00 110.10 ? 654 LEU B O   1 
ATOM   11270 C  CB  . LEU B 1 654 ? 200.029 237.138 178.471 1.00 114.44 ? 654 LEU B CB  1 
ATOM   11271 C  CG  . LEU B 1 654 ? 201.229 236.667 177.649 1.00 108.77 ? 654 LEU B CG  1 
ATOM   11272 C  CD1 . LEU B 1 654 ? 202.090 235.697 178.446 1.00 104.90 ? 654 LEU B CD1 1 
ATOM   11273 C  CD2 . LEU B 1 654 ? 200.773 236.044 176.345 1.00 103.25 ? 654 LEU B CD2 1 
ATOM   11274 N  N   . PRO B 1 655 ? 197.860 238.485 180.155 1.00 117.52 ? 655 PRO B N   1 
ATOM   11275 C  CA  . PRO B 1 655 ? 196.515 239.076 180.090 1.00 115.53 ? 655 PRO B CA  1 
ATOM   11276 C  C   . PRO B 1 655 ? 196.470 240.495 180.629 1.00 111.83 ? 655 PRO B C   1 
ATOM   11277 O  O   . PRO B 1 655 ? 196.109 241.428 179.906 1.00 111.00 ? 655 PRO B O   1 
ATOM   11278 C  CB  . PRO B 1 655 ? 195.667 238.123 180.943 1.00 113.58 ? 655 PRO B CB  1 
ATOM   11279 C  CG  . PRO B 1 655 ? 196.629 237.474 181.861 1.00 111.88 ? 655 PRO B CG  1 
ATOM   11280 C  CD  . PRO B 1 655 ? 197.905 237.345 181.092 1.00 114.31 ? 655 PRO B CD  1 
ATOM   11281 N  N   . ASN B 1 656 ? 196.861 240.667 181.891 1.00 110.64 ? 656 ASN B N   1 
ATOM   11282 C  CA  . ASN B 1 656 ? 196.860 241.993 182.491 1.00 111.64 ? 656 ASN B CA  1 
ATOM   11283 C  C   . ASN B 1 656 ? 197.854 242.909 181.793 1.00 110.91 ? 656 ASN B C   1 
ATOM   11284 O  O   . ASN B 1 656 ? 197.537 244.061 181.471 1.00 109.44 ? 656 ASN B O   1 
ATOM   11285 C  CB  . ASN B 1 656 ? 197.178 241.882 183.980 1.00 115.43 ? 656 ASN B CB  1 
ATOM   11286 C  CG  . ASN B 1 656 ? 198.350 240.959 184.254 1.00 114.43 ? 656 ASN B CG  1 
ATOM   11287 O  OD1 . ASN B 1 656 ? 198.355 239.802 183.832 1.00 111.79 ? 656 ASN B OD1 1 
ATOM   11288 N  ND2 . ASN B 1 656 ? 199.354 241.469 184.957 1.00 112.47 ? 656 ASN B ND2 1 
ATOM   11289 N  N   . GLN B 1 657 ? 199.061 242.405 181.531 1.00 111.08 ? 657 GLN B N   1 
ATOM   11290 C  CA  . GLN B 1 657 ? 200.120 243.252 181.001 1.00 108.66 ? 657 GLN B CA  1 
ATOM   11291 C  C   . GLN B 1 657 ? 199.809 243.785 179.615 1.00 106.26 ? 657 GLN B C   1 
ATOM   11292 O  O   . GLN B 1 657 ? 200.431 244.767 179.197 1.00 103.73 ? 657 GLN B O   1 
ATOM   11293 C  CB  . GLN B 1 657 ? 201.448 242.496 180.979 1.00 107.56 ? 657 GLN B CB  1 
ATOM   11294 C  CG  . GLN B 1 657 ? 202.066 242.313 182.356 1.00 106.80 ? 657 GLN B CG  1 
ATOM   11295 C  CD  . GLN B 1 657 ? 203.566 242.516 182.355 1.00 100.89 ? 657 GLN B CD  1 
ATOM   11296 O  OE1 . GLN B 1 657 ? 204.188 242.631 181.299 1.00 100.92 ? 657 GLN B OE1 1 
ATOM   11297 N  NE2 . GLN B 1 657 ? 204.157 242.562 183.543 1.00 94.93  ? 657 GLN B NE2 1 
ATOM   11298 N  N   . VAL B 1 658 ? 198.876 243.176 178.894 1.00 109.17 ? 658 VAL B N   1 
ATOM   11299 C  CA  . VAL B 1 658 ? 198.413 243.726 177.632 1.00 107.86 ? 658 VAL B CA  1 
ATOM   11300 C  C   . VAL B 1 658 ? 197.122 244.515 177.804 1.00 104.72 ? 658 VAL B C   1 
ATOM   11301 O  O   . VAL B 1 658 ? 196.953 245.561 177.180 1.00 101.52 ? 658 VAL B O   1 
ATOM   11302 C  CB  . VAL B 1 658 ? 198.248 242.607 176.582 1.00 110.03 ? 658 VAL B CB  1 
ATOM   11303 C  CG1 . VAL B 1 658 ? 197.825 243.192 175.245 1.00 102.42 ? 658 VAL B CG1 1 
ATOM   11304 C  CG2 . VAL B 1 658 ? 199.550 241.839 176.426 1.00 108.57 ? 658 VAL B CG2 1 
ATOM   11305 N  N   . SER B 1 659 ? 196.204 244.035 178.648 1.00 106.91 ? 659 SER B N   1 
ATOM   11306 C  CA  . SER B 1 659 ? 194.900 244.677 178.771 1.00 107.88 ? 659 SER B CA  1 
ATOM   11307 C  C   . SER B 1 659 ? 195.013 246.062 179.391 1.00 108.91 ? 659 SER B C   1 
ATOM   11308 O  O   . SER B 1 659 ? 194.338 247.004 178.952 1.00 107.74 ? 659 SER B O   1 
ATOM   11309 C  CB  . SER B 1 659 ? 193.967 243.801 179.603 1.00 108.89 ? 659 SER B CB  1 
ATOM   11310 O  OG  . SER B 1 659 ? 194.458 243.660 180.924 1.00 110.64 ? 659 SER B OG  1 
ATOM   11311 N  N   . ASP B 1 660 ? 195.843 246.203 180.425 1.00 109.51 ? 660 ASP B N   1 
ATOM   11312 C  CA  . ASP B 1 660 ? 196.006 247.509 181.046 1.00 110.00 ? 660 ASP B CA  1 
ATOM   11313 C  C   . ASP B 1 660 ? 196.557 248.516 180.050 1.00 104.82 ? 660 ASP B C   1 
ATOM   11314 O  O   . ASP B 1 660 ? 196.075 249.650 179.972 1.00 105.16 ? 660 ASP B O   1 
ATOM   11315 C  CB  . ASP B 1 660 ? 196.917 247.403 182.268 1.00 115.96 ? 660 ASP B CB  1 
ATOM   11316 C  CG  . ASP B 1 660 ? 196.371 246.459 183.323 1.00 120.36 ? 660 ASP B CG  1 
ATOM   11317 O  OD1 . ASP B 1 660 ? 195.158 246.527 183.612 1.00 120.94 ? 660 ASP B OD1 1 
ATOM   11318 O  OD2 . ASP B 1 660 ? 197.154 245.651 183.864 1.00 121.60 ? 660 ASP B OD2 1 
ATOM   11319 N  N   . ALA B 1 661 ? 197.557 248.115 179.268 1.00 103.06 ? 661 ALA B N   1 
ATOM   11320 C  CA  . ALA B 1 661 ? 198.106 249.019 178.266 1.00 103.42 ? 661 ALA B CA  1 
ATOM   11321 C  C   . ALA B 1 661 ? 197.081 249.325 177.186 1.00 101.73 ? 661 ALA B C   1 
ATOM   11322 O  O   . ALA B 1 661 ? 197.002 250.456 176.696 1.00 102.35 ? 661 ALA B O   1 
ATOM   11323 C  CB  . ALA B 1 661 ? 199.371 248.418 177.654 1.00 102.82 ? 661 ALA B CB  1 
ATOM   11324 N  N   . MET B 1 662 ? 196.288 248.326 176.802 1.00 101.71 ? 662 MET B N   1 
ATOM   11325 C  CA  . MET B 1 662 ? 195.281 248.531 175.771 1.00 105.18 ? 662 MET B CA  1 
ATOM   11326 C  C   . MET B 1 662 ? 194.286 249.595 176.201 1.00 105.03 ? 662 MET B C   1 
ATOM   11327 O  O   . MET B 1 662 ? 194.003 250.541 175.457 1.00 100.53 ? 662 MET B O   1 
ATOM   11328 C  CB  . MET B 1 662 ? 194.553 247.213 175.491 1.00 108.12 ? 662 MET B CB  1 
ATOM   11329 C  CG  . MET B 1 662 ? 193.956 247.026 174.087 1.00 109.64 ? 662 MET B CG  1 
ATOM   11330 S  SD  . MET B 1 662 ? 194.637 247.907 172.657 1.00 116.22 ? 662 MET B SD  1 
ATOM   11331 C  CE  . MET B 1 662 ? 196.393 247.531 172.750 1.00 103.81 ? 662 MET B CE  1 
ATOM   11332 N  N   . HIS B 1 663 ? 193.757 249.464 177.417 1.00 106.78 ? 663 HIS B N   1 
ATOM   11333 C  CA  . HIS B 1 663 ? 192.724 250.386 177.870 1.00 108.23 ? 663 HIS B CA  1 
ATOM   11334 C  C   . HIS B 1 663 ? 193.293 251.740 178.262 1.00 107.62 ? 663 HIS B C   1 
ATOM   11335 O  O   . HIS B 1 663 ? 192.624 252.762 178.079 1.00 106.93 ? 663 HIS B O   1 
ATOM   11336 C  CB  . HIS B 1 663 ? 191.958 249.783 179.046 1.00 107.24 ? 663 HIS B CB  1 
ATOM   11337 C  CG  . HIS B 1 663 ? 190.717 249.052 178.643 1.00 111.51 ? 663 HIS B CG  1 
ATOM   11338 N  ND1 . HIS B 1 663 ? 189.964 249.413 177.547 1.00 113.57 ? 663 HIS B ND1 1 
ATOM   11339 C  CD2 . HIS B 1 663 ? 190.095 247.982 179.191 1.00 112.65 ? 663 HIS B CD2 1 
ATOM   11340 C  CE1 . HIS B 1 663 ? 188.933 248.595 177.435 1.00 112.30 ? 663 HIS B CE1 1 
ATOM   11341 N  NE2 . HIS B 1 663 ? 188.989 247.717 178.421 1.00 112.38 ? 663 HIS B NE2 1 
ATOM   11342 N  N   . ALA B 1 664 ? 194.519 251.770 178.787 1.00 109.29 ? 664 ALA B N   1 
ATOM   11343 C  CA  . ALA B 1 664 ? 195.077 253.011 179.309 1.00 106.86 ? 664 ALA B CA  1 
ATOM   11344 C  C   . ALA B 1 664 ? 195.265 254.057 178.222 1.00 106.33 ? 664 ALA B C   1 
ATOM   11345 O  O   . ALA B 1 664 ? 194.997 255.241 178.454 1.00 108.50 ? 664 ALA B O   1 
ATOM   11346 C  CB  . ALA B 1 664 ? 196.406 252.738 180.009 1.00 103.39 ? 664 ALA B CB  1 
ATOM   11347 N  N   . TRP B 1 665 ? 195.719 253.656 177.043 1.00 105.24 ? 665 TRP B N   1 
ATOM   11348 C  CA  . TRP B 1 665 ? 196.042 254.609 175.998 1.00 106.30 ? 665 TRP B CA  1 
ATOM   11349 C  C   . TRP B 1 665 ? 195.049 254.501 174.851 1.00 107.38 ? 665 TRP B C   1 
ATOM   11350 O  O   . TRP B 1 665 ? 194.123 253.687 174.868 1.00 103.88 ? 665 TRP B O   1 
ATOM   11351 C  CB  . TRP B 1 665 ? 197.473 254.406 175.494 1.00 104.82 ? 665 TRP B CB  1 
ATOM   11352 C  CG  . TRP B 1 665 ? 198.407 255.434 176.028 1.00 104.18 ? 665 TRP B CG  1 
ATOM   11353 C  CD1 . TRP B 1 665 ? 199.409 255.241 176.933 1.00 100.67 ? 665 TRP B CD1 1 
ATOM   11354 C  CD2 . TRP B 1 665 ? 198.424 256.827 175.699 1.00 110.26 ? 665 TRP B CD2 1 
ATOM   11355 N  NE1 . TRP B 1 665 ? 200.048 256.428 177.189 1.00 103.64 ? 665 TRP B NE1 1 
ATOM   11356 C  CE2 . TRP B 1 665 ? 199.465 257.417 176.441 1.00 111.13 ? 665 TRP B CE2 1 
ATOM   11357 C  CE3 . TRP B 1 665 ? 197.662 257.632 174.847 1.00 109.77 ? 665 TRP B CE3 1 
ATOM   11358 C  CZ2 . TRP B 1 665 ? 199.764 258.776 176.357 1.00 111.09 ? 665 TRP B CZ2 1 
ATOM   11359 C  CZ3 . TRP B 1 665 ? 197.960 258.980 174.765 1.00 112.10 ? 665 TRP B CZ3 1 
ATOM   11360 C  CH2 . TRP B 1 665 ? 199.002 259.538 175.515 1.00 111.68 ? 665 TRP B CH2 1 
ATOM   11361 N  N   . GLY B 1 666 ? 195.266 255.347 173.844 1.00 105.09 ? 666 GLY B N   1 
ATOM   11362 C  CA  . GLY B 1 666 ? 194.367 255.453 172.714 1.00 98.55  ? 666 GLY B CA  1 
ATOM   11363 C  C   . GLY B 1 666 ? 194.686 254.482 171.601 1.00 99.00  ? 666 GLY B C   1 
ATOM   11364 O  O   . GLY B 1 666 ? 194.205 254.636 170.476 1.00 94.68  ? 666 GLY B O   1 
ATOM   11365 N  N   . ILE B 1 667 ? 195.502 253.486 171.898 1.00 104.19 ? 667 ILE B N   1 
ATOM   11366 C  CA  . ILE B 1 667 ? 195.856 252.466 170.920 1.00 104.33 ? 667 ILE B CA  1 
ATOM   11367 C  C   . ILE B 1 667 ? 194.663 251.553 170.661 1.00 105.09 ? 667 ILE B C   1 
ATOM   11368 O  O   . ILE B 1 667 ? 193.962 251.123 171.584 1.00 106.66 ? 667 ILE B O   1 
ATOM   11369 C  CB  . ILE B 1 667 ? 197.091 251.680 171.395 1.00 101.66 ? 667 ILE B CB  1 
ATOM   11370 C  CG1 . ILE B 1 667 ? 197.530 250.684 170.319 1.00 97.74  ? 667 ILE B CG1 1 
ATOM   11371 C  CG2 . ILE B 1 667 ? 196.825 251.024 172.740 1.00 99.57  ? 667 ILE B CG2 1 
ATOM   11372 C  CD1 . ILE B 1 667 ? 197.731 251.312 168.956 1.00 93.63  ? 667 ILE B CD1 1 
ATOM   11373 N  N   . ASP B 1 668 ? 194.417 251.269 169.379 1.00 104.74 ? 668 ASP B N   1 
ATOM   11374 C  CA  . ASP B 1 668 ? 193.249 250.497 168.968 1.00 104.82 ? 668 ASP B CA  1 
ATOM   11375 C  C   . ASP B 1 668 ? 193.356 249.010 169.284 1.00 104.71 ? 668 ASP B C   1 
ATOM   11376 O  O   . ASP B 1 668 ? 192.409 248.437 169.835 1.00 104.65 ? 668 ASP B O   1 
ATOM   11377 C  CB  . ASP B 1 668 ? 193.002 250.676 167.468 1.00 104.38 ? 668 ASP B CB  1 
ATOM   11378 C  CG  . ASP B 1 668 ? 191.528 250.712 167.124 1.00 107.29 ? 668 ASP B CG  1 
ATOM   11379 O  OD1 . ASP B 1 668 ? 190.700 250.589 168.051 1.00 108.26 ? 668 ASP B OD1 1 
ATOM   11380 O  OD2 . ASP B 1 668 ? 191.194 250.868 165.931 1.00 105.69 ? 668 ASP B OD2 1 
ATOM   11381 N  N   . GLY B 1 669 ? 194.478 248.368 168.957 1.00 100.82 ? 669 GLY B N   1 
ATOM   11382 C  CA  . GLY B 1 669 ? 194.685 246.961 169.235 1.00 92.59  ? 669 GLY B CA  1 
ATOM   11383 C  C   . GLY B 1 669 ? 194.992 246.107 168.024 1.00 77.85  ? 669 GLY B C   1 
ATOM   11384 O  O   . GLY B 1 669 ? 195.420 244.959 168.188 1.00 72.17  ? 669 GLY B O   1 
ATOM   11385 N  N   . HIS B 1 670 ? 194.783 246.618 166.815 1.00 74.72  ? 670 HIS B N   1 
ATOM   11386 C  CA  . HIS B 1 670 ? 195.112 245.873 165.610 1.00 71.15  ? 670 HIS B CA  1 
ATOM   11387 C  C   . HIS B 1 670 ? 196.380 246.391 164.946 1.00 75.76  ? 670 HIS B C   1 
ATOM   11388 O  O   . HIS B 1 670 ? 196.594 246.148 163.756 1.00 78.45  ? 670 HIS B O   1 
ATOM   11389 C  CB  . HIS B 1 670 ? 193.950 245.910 164.620 1.00 77.82  ? 670 HIS B CB  1 
ATOM   11390 C  CG  . HIS B 1 670 ? 193.615 247.282 164.126 1.00 84.97  ? 670 HIS B CG  1 
ATOM   11391 N  ND1 . HIS B 1 670 ? 193.553 248.382 164.954 1.00 89.48  ? 670 HIS B ND1 1 
ATOM   11392 C  CD2 . HIS B 1 670 ? 193.324 247.729 162.883 1.00 84.52  ? 670 HIS B CD2 1 
ATOM   11393 C  CE1 . HIS B 1 670 ? 193.238 249.448 164.241 1.00 92.23  ? 670 HIS B CE1 1 
ATOM   11394 N  NE2 . HIS B 1 670 ? 193.094 249.079 162.981 1.00 89.57  ? 670 HIS B NE2 1 
ATOM   11395 N  N   . GLN B 1 671 ? 197.225 247.106 165.690 1.00 74.32  ? 671 GLN B N   1 
ATOM   11396 C  CA  . GLN B 1 671 ? 198.425 247.714 165.137 1.00 65.63  ? 671 GLN B CA  1 
ATOM   11397 C  C   . GLN B 1 671 ? 199.726 247.135 165.670 1.00 57.67  ? 671 GLN B C   1 
ATOM   11398 O  O   . GLN B 1 671 ? 200.738 247.213 164.969 1.00 58.55  ? 671 GLN B O   1 
ATOM   11399 C  CB  . GLN B 1 671 ? 198.421 249.228 165.398 1.00 67.25  ? 671 GLN B CB  1 
ATOM   11400 C  CG  . GLN B 1 671 ? 199.257 250.034 164.429 1.00 70.29  ? 671 GLN B CG  1 
ATOM   11401 C  CD  . GLN B 1 671 ? 199.017 251.519 164.567 1.00 77.44  ? 671 GLN B CD  1 
ATOM   11402 O  OE1 . GLN B 1 671 ? 198.302 251.959 165.461 1.00 82.29  ? 671 GLN B OE1 1 
ATOM   11403 N  NE2 . GLN B 1 671 ? 199.624 252.301 163.687 1.00 78.81  ? 671 GLN B NE2 1 
ATOM   11404 N  N   . LEU B 1 672 ? 199.733 246.559 166.867 1.00 52.43  ? 672 LEU B N   1 
ATOM   11405 C  CA  . LEU B 1 672 ? 200.945 246.052 167.489 1.00 50.38  ? 672 LEU B CA  1 
ATOM   11406 C  C   . LEU B 1 672 ? 200.886 244.538 167.590 1.00 52.37  ? 672 LEU B C   1 
ATOM   11407 O  O   . LEU B 1 672 ? 199.834 243.966 167.874 1.00 61.93  ? 672 LEU B O   1 
ATOM   11408 C  CB  . LEU B 1 672 ? 201.152 246.665 168.873 1.00 52.19  ? 672 LEU B CB  1 
ATOM   11409 C  CG  . LEU B 1 672 ? 200.289 246.191 170.034 1.00 57.31  ? 672 LEU B CG  1 
ATOM   11410 C  CD1 . LEU B 1 672 ? 201.012 246.429 171.333 1.00 60.84  ? 672 LEU B CD1 1 
ATOM   11411 C  CD2 . LEU B 1 672 ? 198.971 246.920 170.032 1.00 67.48  ? 672 LEU B CD2 1 
ATOM   11412 N  N   . THR B 1 673 ? 202.016 243.893 167.348 1.00 49.15  ? 673 THR B N   1 
ATOM   11413 C  CA  . THR B 1 673 ? 202.080 242.445 167.258 1.00 48.93  ? 673 THR B CA  1 
ATOM   11414 C  C   . THR B 1 673 ? 203.114 241.909 168.232 1.00 48.30  ? 673 THR B C   1 
ATOM   11415 O  O   . THR B 1 673 ? 204.044 242.612 168.633 1.00 58.96  ? 673 THR B O   1 
ATOM   11416 C  CB  . THR B 1 673 ? 202.423 241.989 165.839 1.00 53.74  ? 673 THR B CB  1 
ATOM   11417 O  OG1 . THR B 1 673 ? 203.649 242.598 165.424 1.00 57.44  ? 673 THR B OG1 1 
ATOM   11418 C  CG2 . THR B 1 673 ? 201.327 242.397 164.878 1.00 57.10  ? 673 THR B CG2 1 
ATOM   11419 N  N   . VAL B 1 674 ? 202.941 240.651 168.612 1.00 41.47  ? 674 VAL B N   1 
ATOM   11420 C  CA  . VAL B 1 674 ? 203.778 240.017 169.616 1.00 45.72  ? 674 VAL B CA  1 
ATOM   11421 C  C   . VAL B 1 674 ? 204.340 238.726 169.046 1.00 47.82  ? 674 VAL B C   1 
ATOM   11422 O  O   . VAL B 1 674 ? 203.646 238.002 168.325 1.00 54.05  ? 674 VAL B O   1 
ATOM   11423 C  CB  . VAL B 1 674 ? 202.991 239.755 170.913 1.00 50.04  ? 674 VAL B CB  1 
ATOM   11424 C  CG1 . VAL B 1 674 ? 202.585 241.069 171.548 1.00 45.70  ? 674 VAL B CG1 1 
ATOM   11425 C  CG2 . VAL B 1 674 ? 201.765 238.930 170.627 1.00 55.66  ? 674 VAL B CG2 1 
ATOM   11426 N  N   . GLU B 1 675 ? 205.599 238.444 169.355 1.00 48.49  ? 675 GLU B N   1 
ATOM   11427 C  CA  . GLU B 1 675 ? 206.266 237.248 168.864 1.00 50.03  ? 675 GLU B CA  1 
ATOM   11428 C  C   . GLU B 1 675 ? 206.442 236.233 169.982 1.00 53.79  ? 675 GLU B C   1 
ATOM   11429 O  O   . GLU B 1 675 ? 206.692 236.600 171.132 1.00 61.86  ? 675 GLU B O   1 
ATOM   11430 C  CB  . GLU B 1 675 ? 207.621 237.591 168.254 1.00 54.01  ? 675 GLU B CB  1 
ATOM   11431 C  CG  . GLU B 1 675 ? 207.626 238.900 167.493 1.00 58.76  ? 675 GLU B CG  1 
ATOM   11432 C  CD  . GLU B 1 675 ? 208.962 239.187 166.845 1.00 62.36  ? 675 GLU B CD  1 
ATOM   11433 O  OE1 . GLU B 1 675 ? 209.886 238.360 166.997 1.00 64.39  ? 675 GLU B OE1 1 
ATOM   11434 O  OE2 . GLU B 1 675 ? 209.090 240.238 166.182 1.00 59.07  ? 675 GLU B OE2 1 
ATOM   11435 N  N   . ILE B 1 676 ? 206.302 234.957 169.639 1.00 51.62  ? 676 ILE B N   1 
ATOM   11436 C  CA  . ILE B 1 676 ? 206.427 233.855 170.585 1.00 60.49  ? 676 ILE B CA  1 
ATOM   11437 C  C   . ILE B 1 676 ? 207.203 232.722 169.927 1.00 73.72  ? 676 ILE B C   1 
ATOM   11438 O  O   . ILE B 1 676 ? 207.002 232.428 168.744 1.00 75.05  ? 676 ILE B O   1 
ATOM   11439 C  CB  . ILE B 1 676 ? 205.049 233.358 171.053 1.00 66.64  ? 676 ILE B CB  1 
ATOM   11440 C  CG1 . ILE B 1 676 ? 204.249 234.501 171.673 1.00 62.60  ? 676 ILE B CG1 1 
ATOM   11441 C  CG2 . ILE B 1 676 ? 205.203 232.237 172.054 1.00 79.07  ? 676 ILE B CG2 1 
ATOM   11442 C  CD1 . ILE B 1 676 ? 203.152 235.033 170.783 1.00 56.39  ? 676 ILE B CD1 1 
ATOM   11443 N  N   . THR B 1 677 ? 208.088 232.083 170.691 1.00 78.44  ? 677 THR B N   1 
ATOM   11444 C  CA  . THR B 1 677 ? 208.845 230.942 170.194 1.00 79.27  ? 677 THR B CA  1 
ATOM   11445 C  C   . THR B 1 677 ? 208.064 229.645 170.375 1.00 87.50  ? 677 THR B C   1 
ATOM   11446 O  O   . THR B 1 677 ? 207.094 229.572 171.133 1.00 90.67  ? 677 THR B O   1 
ATOM   11447 C  CB  . THR B 1 677 ? 210.199 230.830 170.891 1.00 78.77  ? 677 THR B CB  1 
ATOM   11448 O  OG1 . THR B 1 677 ? 210.997 229.851 170.217 1.00 78.27  ? 677 THR B OG1 1 
ATOM   11449 C  CG2 . THR B 1 677 ? 210.024 230.414 172.331 1.00 85.28  ? 677 THR B CG2 1 
ATOM   11450 N  N   . GLU B 1 678 ? 208.508 228.609 169.658 1.00 92.17  ? 678 GLU B N   1 
ATOM   11451 C  CA  . GLU B 1 678 ? 207.769 227.349 169.634 1.00 99.21  ? 678 GLU B CA  1 
ATOM   11452 C  C   . GLU B 1 678 ? 207.820 226.639 170.980 1.00 96.79  ? 678 GLU B C   1 
ATOM   11453 O  O   . GLU B 1 678 ? 206.819 226.065 171.421 1.00 98.53  ? 678 GLU B O   1 
ATOM   11454 C  CB  . GLU B 1 678 ? 208.310 226.444 168.526 1.00 95.46  ? 678 GLU B CB  1 
ATOM   11455 C  CG  . GLU B 1 678 ? 209.750 226.005 168.718 1.00 98.35  ? 678 GLU B CG  1 
ATOM   11456 C  CD  . GLU B 1 678 ? 209.856 224.618 169.315 1.00 100.72 ? 678 GLU B CD  1 
ATOM   11457 O  OE1 . GLU B 1 678 ? 208.920 223.815 169.122 1.00 96.80  ? 678 GLU B OE1 1 
ATOM   11458 O  OE2 . GLU B 1 678 ? 210.874 224.330 169.979 1.00 100.75 ? 678 GLU B OE2 1 
ATOM   11459 N  N   . SER B 1 679 ? 208.973 226.665 171.649 1.00 94.36  ? 679 SER B N   1 
ATOM   11460 C  CA  . SER B 1 679 ? 209.079 226.017 172.950 1.00 98.04  ? 679 SER B CA  1 
ATOM   11461 C  C   . SER B 1 679 ? 208.147 226.671 173.956 1.00 100.52 ? 679 SER B C   1 
ATOM   11462 O  O   . SER B 1 679 ? 207.522 225.989 174.774 1.00 105.35 ? 679 SER B O   1 
ATOM   11463 C  CB  . SER B 1 679 ? 210.525 226.063 173.444 1.00 100.38 ? 679 SER B CB  1 
ATOM   11464 O  OG  . SER B 1 679 ? 211.124 227.314 173.153 1.00 99.90  ? 679 SER B OG  1 
ATOM   11465 N  N   . MET B 1 680 ? 208.029 227.992 173.904 1.00 98.67  ? 680 MET B N   1 
ATOM   11466 C  CA  . MET B 1 680 ? 207.136 228.686 174.814 1.00 105.72 ? 680 MET B CA  1 
ATOM   11467 C  C   . MET B 1 680 ? 205.684 228.588 174.378 1.00 105.14 ? 680 MET B C   1 
ATOM   11468 O  O   . MET B 1 680 ? 204.808 229.106 175.075 1.00 112.31 ? 680 MET B O   1 
ATOM   11469 C  CB  . MET B 1 680 ? 207.560 230.154 174.924 1.00 106.13 ? 680 MET B CB  1 
ATOM   11470 C  CG  . MET B 1 680 ? 207.121 230.864 176.194 1.00 105.66 ? 680 MET B CG  1 
ATOM   11471 S  SD  . MET B 1 680 ? 207.808 232.529 176.317 1.00 110.02 ? 680 MET B SD  1 
ATOM   11472 C  CE  . MET B 1 680 ? 207.752 233.059 174.608 1.00 90.73  ? 680 MET B CE  1 
ATOM   11473 N  N   . MET B 1 681 ? 205.401 227.927 173.257 1.00 98.75  ? 681 MET B N   1 
ATOM   11474 C  CA  . MET B 1 681 ? 204.033 227.905 172.757 1.00 103.11 ? 681 MET B CA  1 
ATOM   11475 C  C   . MET B 1 681 ? 203.204 226.855 173.488 1.00 105.65 ? 681 MET B C   1 
ATOM   11476 O  O   . MET B 1 681 ? 202.153 227.168 174.057 1.00 108.30 ? 681 MET B O   1 
ATOM   11477 C  CB  . MET B 1 681 ? 204.038 227.652 171.248 1.00 105.34 ? 681 MET B CB  1 
ATOM   11478 C  CG  . MET B 1 681 ? 202.679 227.362 170.605 1.00 109.58 ? 681 MET B CG  1 
ATOM   11479 S  SD  . MET B 1 681 ? 201.234 228.233 171.255 1.00 118.19 ? 681 MET B SD  1 
ATOM   11480 C  CE  . MET B 1 681 ? 201.736 229.946 171.081 1.00 104.74 ? 681 MET B CE  1 
ATOM   11481 N  N   . MET B 1 682 ? 203.668 225.599 173.497 1.00 106.47 ? 682 MET B N   1 
ATOM   11482 C  CA  . MET B 1 682 ? 202.906 224.538 174.145 1.00 108.45 ? 682 MET B CA  1 
ATOM   11483 C  C   . MET B 1 682 ? 203.745 223.715 175.117 1.00 113.15 ? 682 MET B C   1 
ATOM   11484 O  O   . MET B 1 682 ? 203.411 222.553 175.370 1.00 114.46 ? 682 MET B O   1 
ATOM   11485 C  CB  . MET B 1 682 ? 202.289 223.576 173.123 1.00 108.99 ? 682 MET B CB  1 
ATOM   11486 C  CG  . MET B 1 682 ? 203.271 223.017 172.101 1.00 111.43 ? 682 MET B CG  1 
ATOM   11487 S  SD  . MET B 1 682 ? 202.496 222.494 170.556 1.00 119.39 ? 682 MET B SD  1 
ATOM   11488 C  CE  . MET B 1 682 ? 202.503 224.006 169.606 1.00 97.18  ? 682 MET B CE  1 
ATOM   11489 N  N   . GLU B 1 683 ? 204.820 224.269 175.665 1.00 118.24 ? 683 GLU B N   1 
ATOM   11490 C  CA  . GLU B 1 683 ? 205.670 223.545 176.598 1.00 128.16 ? 683 GLU B CA  1 
ATOM   11491 C  C   . GLU B 1 683 ? 205.836 224.350 177.880 1.00 133.81 ? 683 GLU B C   1 
ATOM   11492 O  O   . GLU B 1 683 ? 205.511 225.539 177.943 1.00 130.94 ? 683 GLU B O   1 
ATOM   11493 C  CB  . GLU B 1 683 ? 207.041 223.236 175.981 1.00 126.67 ? 683 GLU B CB  1 
ATOM   11494 C  CG  . GLU B 1 683 ? 206.990 222.346 174.752 1.00 124.03 ? 683 GLU B CG  1 
ATOM   11495 C  CD  . GLU B 1 683 ? 208.340 221.743 174.414 1.00 129.39 ? 683 GLU B CD  1 
ATOM   11496 O  OE1 . GLU B 1 683 ? 209.353 222.472 174.486 1.00 126.88 ? 683 GLU B OE1 1 
ATOM   11497 O  OE2 . GLU B 1 683 ? 208.389 220.542 174.076 1.00 133.00 ? 683 GLU B OE2 1 
ATOM   11498 N  N   . HIS B 1 684 ? 206.351 223.674 178.909 1.00 135.84 ? 684 HIS B N   1 
ATOM   11499 C  CA  . HIS B 1 684 ? 206.515 224.247 180.246 1.00 139.79 ? 684 HIS B CA  1 
ATOM   11500 C  C   . HIS B 1 684 ? 205.178 224.766 180.778 1.00 139.97 ? 684 HIS B C   1 
ATOM   11501 O  O   . HIS B 1 684 ? 205.038 225.935 181.129 1.00 141.29 ? 684 HIS B O   1 
ATOM   11502 C  CB  . HIS B 1 684 ? 207.582 225.348 180.252 1.00 141.30 ? 684 HIS B CB  1 
ATOM   11503 C  CG  . HIS B 1 684 ? 208.912 224.905 179.726 1.00 141.53 ? 684 HIS B CG  1 
ATOM   11504 N  ND1 . HIS B 1 684 ? 209.890 225.794 179.335 1.00 141.11 ? 684 HIS B ND1 1 
ATOM   11505 C  CD2 . HIS B 1 684 ? 209.427 223.668 179.531 1.00 140.47 ? 684 HIS B CD2 1 
ATOM   11506 C  CE1 . HIS B 1 684 ? 210.950 225.123 178.919 1.00 137.00 ? 684 HIS B CE1 1 
ATOM   11507 N  NE2 . HIS B 1 684 ? 210.695 223.832 179.028 1.00 140.01 ? 684 HIS B NE2 1 
ATOM   11508 N  N   . ASP B 1 685 ? 204.223 223.831 180.871 1.00 137.14 ? 685 ASP B N   1 
ATOM   11509 C  CA  . ASP B 1 685 ? 202.792 223.956 181.171 1.00 134.24 ? 685 ASP B CA  1 
ATOM   11510 C  C   . ASP B 1 685 ? 202.033 224.400 179.924 1.00 129.42 ? 685 ASP B C   1 
ATOM   11511 O  O   . ASP B 1 685 ? 202.642 224.672 178.885 1.00 126.74 ? 685 ASP B O   1 
ATOM   11512 C  CB  . ASP B 1 685 ? 202.492 224.893 182.364 1.00 136.38 ? 685 ASP B CB  1 
ATOM   11513 C  CG  . ASP B 1 685 ? 202.390 226.388 181.996 1.00 135.45 ? 685 ASP B CG  1 
ATOM   11514 O  OD1 . ASP B 1 685 ? 202.743 226.828 180.882 1.00 136.63 ? 685 ASP B OD1 1 
ATOM   11515 O  OD2 . ASP B 1 685 ? 201.930 227.151 182.872 1.00 129.58 ? 685 ASP B OD2 1 
ATOM   11516 N  N   . THR B 1 686 ? 200.704 224.473 180.016 1.00 126.77 ? 686 THR B N   1 
ATOM   11517 C  CA  . THR B 1 686 ? 199.875 224.842 178.876 1.00 122.50 ? 686 THR B CA  1 
ATOM   11518 C  C   . THR B 1 686 ? 198.891 225.960 179.196 1.00 122.19 ? 686 THR B C   1 
ATOM   11519 O  O   . THR B 1 686 ? 198.072 226.308 178.337 1.00 117.56 ? 686 THR B O   1 
ATOM   11520 C  CB  . THR B 1 686 ? 199.109 223.623 178.350 1.00 120.34 ? 686 THR B CB  1 
ATOM   11521 O  OG1 . THR B 1 686 ? 198.556 222.892 179.453 1.00 122.56 ? 686 THR B OG1 1 
ATOM   11522 C  CG2 . THR B 1 686 ? 200.036 222.714 177.560 1.00 117.62 ? 686 THR B CG2 1 
ATOM   11523 N  N   . GLU B 1 687 ? 198.937 226.525 180.405 1.00 124.96 ? 687 GLU B N   1 
ATOM   11524 C  CA  . GLU B 1 687 ? 198.092 227.677 180.705 1.00 122.61 ? 687 GLU B CA  1 
ATOM   11525 C  C   . GLU B 1 687 ? 198.437 228.853 179.807 1.00 118.43 ? 687 GLU B C   1 
ATOM   11526 O  O   . GLU B 1 687 ? 197.562 229.660 179.461 1.00 117.84 ? 687 GLU B O   1 
ATOM   11527 C  CB  . GLU B 1 687 ? 198.229 228.066 182.177 1.00 124.45 ? 687 GLU B CB  1 
ATOM   11528 C  CG  . GLU B 1 687 ? 196.994 228.737 182.758 1.00 124.38 ? 687 GLU B CG  1 
ATOM   11529 C  CD  . GLU B 1 687 ? 197.035 228.826 184.271 1.00 131.08 ? 687 GLU B CD  1 
ATOM   11530 O  OE1 . GLU B 1 687 ? 198.009 229.393 184.809 1.00 128.50 ? 687 GLU B OE1 1 
ATOM   11531 O  OE2 . GLU B 1 687 ? 196.092 228.330 184.922 1.00 137.18 ? 687 GLU B OE2 1 
ATOM   11532 N  N   . ILE B 1 688 ? 199.704 228.952 179.404 1.00 116.06 ? 688 ILE B N   1 
ATOM   11533 C  CA  . ILE B 1 688 ? 200.135 230.046 178.549 1.00 111.82 ? 688 ILE B CA  1 
ATOM   11534 C  C   . ILE B 1 688 ? 199.451 229.961 177.195 1.00 107.02 ? 688 ILE B C   1 
ATOM   11535 O  O   . ILE B 1 688 ? 199.244 230.982 176.534 1.00 103.81 ? 688 ILE B O   1 
ATOM   11536 C  CB  . ILE B 1 688 ? 201.672 230.037 178.437 1.00 110.46 ? 688 ILE B CB  1 
ATOM   11537 C  CG1 . ILE B 1 688 ? 202.150 230.890 177.263 1.00 110.35 ? 688 ILE B CG1 1 
ATOM   11538 C  CG2 . ILE B 1 688 ? 202.170 228.615 178.284 1.00 112.69 ? 688 ILE B CG2 1 
ATOM   11539 C  CD1 . ILE B 1 688 ? 203.646 231.038 177.199 1.00 110.55 ? 688 ILE B CD1 1 
ATOM   11540 N  N   . PHE B 1 689 ? 199.050 228.760 176.773 1.00 110.78 ? 689 PHE B N   1 
ATOM   11541 C  CA  . PHE B 1 689 ? 198.375 228.632 175.485 1.00 112.69 ? 689 PHE B CA  1 
ATOM   11542 C  C   . PHE B 1 689 ? 197.080 229.439 175.458 1.00 111.02 ? 689 PHE B C   1 
ATOM   11543 O  O   . PHE B 1 689 ? 196.880 230.285 174.579 1.00 108.94 ? 689 PHE B O   1 
ATOM   11544 C  CB  . PHE B 1 689 ? 198.102 227.161 175.171 1.00 111.46 ? 689 PHE B CB  1 
ATOM   11545 C  CG  . PHE B 1 689 ? 197.414 226.946 173.855 1.00 107.51 ? 689 PHE B CG  1 
ATOM   11546 C  CD1 . PHE B 1 689 ? 197.921 227.508 172.698 1.00 103.25 ? 689 PHE B CD1 1 
ATOM   11547 C  CD2 . PHE B 1 689 ? 196.255 226.197 173.779 1.00 108.19 ? 689 PHE B CD2 1 
ATOM   11548 C  CE1 . PHE B 1 689 ? 197.288 227.320 171.486 1.00 101.99 ? 689 PHE B CE1 1 
ATOM   11549 C  CE2 . PHE B 1 689 ? 195.617 226.005 172.570 1.00 105.32 ? 689 PHE B CE2 1 
ATOM   11550 C  CZ  . PHE B 1 689 ? 196.134 226.568 171.422 1.00 102.56 ? 689 PHE B CZ  1 
ATOM   11551 N  N   . LYS B 1 690 ? 196.198 229.223 176.432 1.00 109.89 ? 690 LYS B N   1 
ATOM   11552 C  CA  . LYS B 1 690 ? 194.997 230.046 176.468 1.00 103.76 ? 690 LYS B CA  1 
ATOM   11553 C  C   . LYS B 1 690 ? 195.268 231.462 176.949 1.00 100.14 ? 690 LYS B C   1 
ATOM   11554 O  O   . LYS B 1 690 ? 194.493 232.367 176.622 1.00 98.49  ? 690 LYS B O   1 
ATOM   11555 C  CB  . LYS B 1 690 ? 193.903 229.395 177.316 1.00 104.78 ? 690 LYS B CB  1 
ATOM   11556 C  CG  . LYS B 1 690 ? 194.296 228.966 178.710 1.00 109.67 ? 690 LYS B CG  1 
ATOM   11557 C  CD  . LYS B 1 690 ? 193.452 227.754 179.089 1.00 111.65 ? 690 LYS B CD  1 
ATOM   11558 C  CE  . LYS B 1 690 ? 194.038 226.947 180.224 1.00 111.93 ? 690 LYS B CE  1 
ATOM   11559 N  NZ  . LYS B 1 690 ? 195.395 226.479 179.873 1.00 111.86 ? 690 LYS B NZ  1 
ATOM   11560 N  N   . ARG B 1 691 ? 196.357 231.688 177.682 1.00 103.34 ? 691 ARG B N   1 
ATOM   11561 C  CA  . ARG B 1 691 ? 196.704 233.065 178.010 1.00 105.66 ? 691 ARG B CA  1 
ATOM   11562 C  C   . ARG B 1 691 ? 197.089 233.848 176.762 1.00 104.67 ? 691 ARG B C   1 
ATOM   11563 O  O   . ARG B 1 691 ? 196.947 235.075 176.730 1.00 105.16 ? 691 ARG B O   1 
ATOM   11564 C  CB  . ARG B 1 691 ? 197.827 233.098 179.045 1.00 109.96 ? 691 ARG B CB  1 
ATOM   11565 C  CG  . ARG B 1 691 ? 197.327 232.972 180.477 1.00 111.59 ? 691 ARG B CG  1 
ATOM   11566 C  CD  . ARG B 1 691 ? 198.326 233.536 181.471 1.00 113.58 ? 691 ARG B CD  1 
ATOM   11567 N  NE  . ARG B 1 691 ? 199.276 232.528 181.927 1.00 113.94 ? 691 ARG B NE  1 
ATOM   11568 C  CZ  . ARG B 1 691 ? 199.093 231.756 182.989 1.00 116.75 ? 691 ARG B CZ  1 
ATOM   11569 N  NH1 . ARG B 1 691 ? 198.005 231.851 183.734 1.00 120.77 ? 691 ARG B NH1 1 
ATOM   11570 N  NH2 . ARG B 1 691 ? 200.028 230.866 183.312 1.00 116.84 ? 691 ARG B NH2 1 
ATOM   11571 N  N   . ILE B 1 692 ? 197.588 233.159 175.738 1.00 101.86 ? 692 ILE B N   1 
ATOM   11572 C  CA  . ILE B 1 692 ? 197.819 233.796 174.447 1.00 98.02  ? 692 ILE B CA  1 
ATOM   11573 C  C   . ILE B 1 692 ? 196.534 233.820 173.635 1.00 93.73  ? 692 ILE B C   1 
ATOM   11574 O  O   . ILE B 1 692 ? 196.307 234.741 172.839 1.00 92.47  ? 692 ILE B O   1 
ATOM   11575 C  CB  . ILE B 1 692 ? 198.948 233.082 173.685 1.00 94.90  ? 692 ILE B CB  1 
ATOM   11576 C  CG1 . ILE B 1 692 ? 200.225 233.055 174.516 1.00 99.33  ? 692 ILE B CG1 1 
ATOM   11577 C  CG2 . ILE B 1 692 ? 199.238 233.793 172.405 1.00 84.87  ? 692 ILE B CG2 1 
ATOM   11578 C  CD1 . ILE B 1 692 ? 201.265 232.106 173.988 1.00 96.07  ? 692 ILE B CD1 1 
ATOM   11579 N  N   . GLN B 1 693 ? 195.680 232.817 173.820 1.00 93.34  ? 693 GLN B N   1 
ATOM   11580 C  CA  . GLN B 1 693 ? 194.422 232.785 173.089 1.00 96.09  ? 693 GLN B CA  1 
ATOM   11581 C  C   . GLN B 1 693 ? 193.553 233.982 173.442 1.00 94.12  ? 693 GLN B C   1 
ATOM   11582 O  O   . GLN B 1 693 ? 192.915 234.572 172.566 1.00 94.95  ? 693 GLN B O   1 
ATOM   11583 C  CB  . GLN B 1 693 ? 193.683 231.478 173.373 1.00 103.28 ? 693 GLN B CB  1 
ATOM   11584 C  CG  . GLN B 1 693 ? 194.182 230.294 172.557 1.00 106.05 ? 693 GLN B CG  1 
ATOM   11585 C  CD  . GLN B 1 693 ? 193.469 230.154 171.225 1.00 101.29 ? 693 GLN B CD  1 
ATOM   11586 O  OE1 . GLN B 1 693 ? 192.728 231.044 170.807 1.00 102.54 ? 693 GLN B OE1 1 
ATOM   11587 N  NE2 . GLN B 1 693 ? 193.694 229.034 170.549 1.00 91.25  ? 693 GLN B NE2 1 
ATOM   11588 N  N   . ILE B 1 694 ? 193.510 234.356 174.721 1.00 95.72  ? 694 ILE B N   1 
ATOM   11589 C  CA  . ILE B 1 694 ? 192.690 235.501 175.115 1.00 95.41  ? 694 ILE B CA  1 
ATOM   11590 C  C   . ILE B 1 694 ? 193.258 236.788 174.532 1.00 90.81  ? 694 ILE B C   1 
ATOM   11591 O  O   . ILE B 1 694 ? 192.514 237.690 174.131 1.00 90.24  ? 694 ILE B O   1 
ATOM   11592 C  CB  . ILE B 1 694 ? 192.559 235.583 176.646 1.00 97.02  ? 694 ILE B CB  1 
ATOM   11593 C  CG1 . ILE B 1 694 ? 193.925 235.451 177.318 1.00 97.76  ? 694 ILE B CG1 1 
ATOM   11594 C  CG2 . ILE B 1 694 ? 191.600 234.515 177.153 1.00 95.90  ? 694 ILE B CG2 1 
ATOM   11595 C  CD1 . ILE B 1 694 ? 193.851 235.206 178.809 1.00 95.25  ? 694 ILE B CD1 1 
ATOM   11596 N  N   . LEU B 1 695 ? 194.586 236.891 174.474 1.00 91.67  ? 695 LEU B N   1 
ATOM   11597 C  CA  . LEU B 1 695 ? 195.217 238.050 173.856 1.00 94.24  ? 695 LEU B CA  1 
ATOM   11598 C  C   . LEU B 1 695 ? 194.856 238.131 172.380 1.00 91.58  ? 695 LEU B C   1 
ATOM   11599 O  O   . LEU B 1 695 ? 194.633 239.219 171.840 1.00 85.94  ? 695 LEU B O   1 
ATOM   11600 C  CB  . LEU B 1 695 ? 196.732 237.968 174.068 1.00 96.72  ? 695 LEU B CB  1 
ATOM   11601 C  CG  . LEU B 1 695 ? 197.697 239.125 173.807 1.00 93.83  ? 695 LEU B CG  1 
ATOM   11602 C  CD1 . LEU B 1 695 ? 199.079 238.741 174.309 1.00 96.06  ? 695 LEU B CD1 1 
ATOM   11603 C  CD2 . LEU B 1 695 ? 197.783 239.455 172.347 1.00 83.23  ? 695 LEU B CD2 1 
ATOM   11604 N  N   . ARG B 1 696 ? 194.808 236.982 171.708 1.00 94.57  ? 696 ARG B N   1 
ATOM   11605 C  CA  . ARG B 1 696 ? 194.306 236.957 170.339 1.00 93.63  ? 696 ARG B CA  1 
ATOM   11606 C  C   . ARG B 1 696 ? 192.849 237.391 170.287 1.00 98.33  ? 696 ARG B C   1 
ATOM   11607 O  O   . ARG B 1 696 ? 192.443 238.100 169.359 1.00 96.66  ? 696 ARG B O   1 
ATOM   11608 C  CB  . ARG B 1 696 ? 194.459 235.560 169.747 1.00 88.59  ? 696 ARG B CB  1 
ATOM   11609 C  CG  . ARG B 1 696 ? 194.442 235.519 168.241 1.00 79.03  ? 696 ARG B CG  1 
ATOM   11610 C  CD  . ARG B 1 696 ? 195.833 235.738 167.694 1.00 72.32  ? 696 ARG B CD  1 
ATOM   11611 N  NE  . ARG B 1 696 ? 195.822 236.068 166.276 1.00 70.83  ? 696 ARG B NE  1 
ATOM   11612 C  CZ  . ARG B 1 696 ? 195.449 237.239 165.781 1.00 73.63  ? 696 ARG B CZ  1 
ATOM   11613 N  NH1 . ARG B 1 696 ? 195.033 238.220 166.564 1.00 76.80  ? 696 ARG B NH1 1 
ATOM   11614 N  NH2 . ARG B 1 696 ? 195.494 237.430 164.466 1.00 71.33  ? 696 ARG B NH2 1 
ATOM   11615 N  N   . ASP B 1 697 ? 192.057 236.967 171.274 1.00 100.92 ? 697 ASP B N   1 
ATOM   11616 C  CA  . ASP B 1 697 ? 190.665 237.393 171.371 1.00 99.51  ? 697 ASP B CA  1 
ATOM   11617 C  C   . ASP B 1 697 ? 190.570 238.906 171.488 1.00 96.51  ? 697 ASP B C   1 
ATOM   11618 O  O   . ASP B 1 697 ? 189.588 239.511 171.044 1.00 99.41  ? 697 ASP B O   1 
ATOM   11619 C  CB  . ASP B 1 697 ? 189.995 236.717 172.565 1.00 98.45  ? 697 ASP B CB  1 
ATOM   11620 C  CG  . ASP B 1 697 ? 189.918 235.212 172.414 1.00 101.42 ? 697 ASP B CG  1 
ATOM   11621 O  OD1 . ASP B 1 697 ? 189.991 234.724 171.267 1.00 103.55 ? 697 ASP B OD1 1 
ATOM   11622 O  OD2 . ASP B 1 697 ? 189.790 234.516 173.443 1.00 98.17  ? 697 ASP B OD2 1 
ATOM   11623 N  N   . MET B 1 698 ? 191.577 239.531 172.091 1.00 93.66  ? 698 MET B N   1 
ATOM   11624 C  CA  . MET B 1 698 ? 191.683 240.982 172.077 1.00 96.18  ? 698 MET B CA  1 
ATOM   11625 C  C   . MET B 1 698 ? 192.023 241.532 170.697 1.00 89.19  ? 698 MET B C   1 
ATOM   11626 O  O   . MET B 1 698 ? 191.790 242.719 170.450 1.00 86.12  ? 698 MET B O   1 
ATOM   11627 C  CB  . MET B 1 698 ? 192.731 241.444 173.092 1.00 98.62  ? 698 MET B CB  1 
ATOM   11628 C  CG  . MET B 1 698 ? 192.268 242.580 173.990 1.00 103.45 ? 698 MET B CG  1 
ATOM   11629 S  SD  . MET B 1 698 ? 190.732 242.198 174.855 1.00 112.37 ? 698 MET B SD  1 
ATOM   11630 C  CE  . MET B 1 698 ? 191.344 241.894 176.511 1.00 105.56 ? 698 MET B CE  1 
ATOM   11631 N  N   . GLY B 1 699 ? 192.563 240.713 169.801 1.00 83.59  ? 699 GLY B N   1 
ATOM   11632 C  CA  . GLY B 1 699 ? 192.795 241.129 168.434 1.00 83.55  ? 699 GLY B CA  1 
ATOM   11633 C  C   . GLY B 1 699 ? 194.211 241.522 168.063 1.00 89.75  ? 699 GLY B C   1 
ATOM   11634 O  O   . GLY B 1 699 ? 194.403 242.118 166.997 1.00 90.68  ? 699 GLY B O   1 
ATOM   11635 N  N   . VAL B 1 700 ? 195.203 241.215 168.899 1.00 88.30  ? 700 VAL B N   1 
ATOM   11636 C  CA  . VAL B 1 700 ? 196.586 241.556 168.581 1.00 76.51  ? 700 VAL B CA  1 
ATOM   11637 C  C   . VAL B 1 700 ? 197.206 240.456 167.733 1.00 73.77  ? 700 VAL B C   1 
ATOM   11638 O  O   . VAL B 1 700 ? 197.123 239.269 168.071 1.00 80.46  ? 700 VAL B O   1 
ATOM   11639 C  CB  . VAL B 1 700 ? 197.390 241.782 169.866 1.00 71.94  ? 700 VAL B CB  1 
ATOM   11640 C  CG1 . VAL B 1 700 ? 198.869 241.569 169.613 1.00 64.25  ? 700 VAL B CG1 1 
ATOM   11641 C  CG2 . VAL B 1 700 ? 197.136 243.179 170.408 1.00 79.55  ? 700 VAL B CG2 1 
ATOM   11642 N  N   . GLY B 1 701 ? 197.836 240.846 166.628 1.00 65.78  ? 701 GLY B N   1 
ATOM   11643 C  CA  . GLY B 1 701 ? 198.437 239.862 165.749 1.00 66.44  ? 701 GLY B CA  1 
ATOM   11644 C  C   . GLY B 1 701 ? 199.592 239.144 166.418 1.00 65.89  ? 701 GLY B C   1 
ATOM   11645 O  O   . GLY B 1 701 ? 200.245 239.671 167.320 1.00 67.11  ? 701 GLY B O   1 
ATOM   11646 N  N   . LEU B 1 702 ? 199.847 237.921 165.965 1.00 56.98  ? 702 LEU B N   1 
ATOM   11647 C  CA  . LEU B 1 702 ? 200.865 237.074 166.562 1.00 48.79  ? 702 LEU B CA  1 
ATOM   11648 C  C   . LEU B 1 702 ? 201.959 236.775 165.543 1.00 45.93  ? 702 LEU B C   1 
ATOM   11649 O  O   . LEU B 1 702 ? 201.924 237.238 164.404 1.00 49.04  ? 702 LEU B O   1 
ATOM   11650 C  CB  . LEU B 1 702 ? 200.235 235.794 167.106 1.00 47.73  ? 702 LEU B CB  1 
ATOM   11651 C  CG  . LEU B 1 702 ? 200.229 235.696 168.628 1.00 49.45  ? 702 LEU B CG  1 
ATOM   11652 C  CD1 . LEU B 1 702 ? 199.294 236.717 169.206 1.00 54.21  ? 702 LEU B CD1 1 
ATOM   11653 C  CD2 . LEU B 1 702 ? 199.815 234.321 169.047 1.00 56.27  ? 702 LEU B CD2 1 
ATOM   11654 N  N   . SER B 1 703 ? 202.957 236.010 165.980 1.00 43.36  ? 703 SER B N   1 
ATOM   11655 C  CA  . SER B 1 703 ? 204.102 235.661 165.152 1.00 42.06  ? 703 SER B CA  1 
ATOM   11656 C  C   . SER B 1 703 ? 204.862 234.515 165.792 1.00 47.79  ? 703 SER B C   1 
ATOM   11657 O  O   . SER B 1 703 ? 205.244 234.588 166.963 1.00 57.65  ? 703 SER B O   1 
ATOM   11658 C  CB  . SER B 1 703 ? 205.033 236.847 164.957 1.00 44.96  ? 703 SER B CB  1 
ATOM   11659 O  OG  . SER B 1 703 ? 206.048 236.524 164.028 1.00 48.37  ? 703 SER B OG  1 
ATOM   11660 N  N   . VAL B 1 704 ? 205.087 233.454 165.032 1.00 44.76  ? 704 VAL B N   1 
ATOM   11661 C  CA  . VAL B 1 704 ? 205.604 232.207 165.560 1.00 49.90  ? 704 VAL B CA  1 
ATOM   11662 C  C   . VAL B 1 704 ? 206.963 231.972 164.922 1.00 51.97  ? 704 VAL B C   1 
ATOM   11663 O  O   . VAL B 1 704 ? 207.278 232.521 163.870 1.00 55.75  ? 704 VAL B O   1 
ATOM   11664 C  CB  . VAL B 1 704 ? 204.616 231.046 165.312 1.00 58.44  ? 704 VAL B CB  1 
ATOM   11665 C  CG1 . VAL B 1 704 ? 205.285 229.675 165.268 1.00 65.67  ? 704 VAL B CG1 1 
ATOM   11666 C  CG2 . VAL B 1 704 ? 203.527 231.067 166.374 1.00 59.63  ? 704 VAL B CG2 1 
ATOM   11667 N  N   . ASP B 1 705 ? 207.781 231.161 165.580 1.00 54.35  ? 705 ASP B N   1 
ATOM   11668 C  CA  . ASP B 1 705 ? 209.140 230.920 165.134 1.00 58.02  ? 705 ASP B CA  1 
ATOM   11669 C  C   . ASP B 1 705 ? 209.296 229.623 164.357 1.00 64.40  ? 705 ASP B C   1 
ATOM   11670 O  O   . ASP B 1 705 ? 209.841 229.639 163.254 1.00 64.94  ? 705 ASP B O   1 
ATOM   11671 C  CB  . ASP B 1 705 ? 210.093 230.928 166.333 1.00 69.65  ? 705 ASP B CB  1 
ATOM   11672 C  CG  . ASP B 1 705 ? 209.994 232.204 167.139 1.00 79.16  ? 705 ASP B CG  1 
ATOM   11673 O  OD1 . ASP B 1 705 ? 210.759 232.364 168.115 1.00 83.10  ? 705 ASP B OD1 1 
ATOM   11674 O  OD2 . ASP B 1 705 ? 209.140 233.045 166.801 1.00 74.68  ? 705 ASP B OD2 1 
ATOM   11675 N  N   . ASP B 1 706 ? 208.827 228.495 164.890 1.00 71.34  ? 706 ASP B N   1 
ATOM   11676 C  CA  . ASP B 1 706 ? 209.109 227.211 164.259 1.00 74.14  ? 706 ASP B CA  1 
ATOM   11677 C  C   . ASP B 1 706 ? 207.838 226.424 163.961 1.00 77.08  ? 706 ASP B C   1 
ATOM   11678 O  O   . ASP B 1 706 ? 207.806 225.632 163.015 1.00 77.35  ? 706 ASP B O   1 
ATOM   11679 C  CB  . ASP B 1 706 ? 210.040 226.389 165.153 1.00 77.69  ? 706 ASP B CB  1 
ATOM   11680 C  CG  . ASP B 1 706 ? 210.404 225.040 164.553 1.00 84.38  ? 706 ASP B CG  1 
ATOM   11681 O  OD1 . ASP B 1 706 ? 210.426 224.914 163.310 1.00 83.94  ? 706 ASP B OD1 1 
ATOM   11682 O  OD2 . ASP B 1 706 ? 210.677 224.102 165.329 1.00 87.57  ? 706 ASP B OD2 1 
ATOM   11683 N  N   . PHE B 1 707 ? 206.801 226.611 164.778 1.00 76.78  ? 707 PHE B N   1 
ATOM   11684 C  CA  . PHE B 1 707 ? 205.490 225.979 164.587 1.00 72.00  ? 707 PHE B CA  1 
ATOM   11685 C  C   . PHE B 1 707 ? 205.565 224.453 164.567 1.00 69.28  ? 707 PHE B C   1 
ATOM   11686 O  O   . PHE B 1 707 ? 204.606 223.771 164.206 1.00 69.28  ? 707 PHE B O   1 
ATOM   11687 C  CB  . PHE B 1 707 ? 204.770 226.572 163.358 1.00 74.02  ? 707 PHE B CB  1 
ATOM   11688 C  CG  . PHE B 1 707 ? 205.193 226.042 161.999 1.00 77.44  ? 707 PHE B CG  1 
ATOM   11689 C  CD1 . PHE B 1 707 ? 205.716 226.921 161.065 1.00 73.33  ? 707 PHE B CD1 1 
ATOM   11690 C  CD2 . PHE B 1 707 ? 204.994 224.728 161.612 1.00 80.04  ? 707 PHE B CD2 1 
ATOM   11691 C  CE1 . PHE B 1 707 ? 206.083 226.491 159.807 1.00 69.73  ? 707 PHE B CE1 1 
ATOM   11692 C  CE2 . PHE B 1 707 ? 205.371 224.291 160.356 1.00 80.36  ? 707 PHE B CE2 1 
ATOM   11693 C  CZ  . PHE B 1 707 ? 205.915 225.178 159.452 1.00 73.79  ? 707 PHE B CZ  1 
ATOM   11694 N  N   . GLY B 1 708 ? 206.661 223.901 165.066 1.00 76.99  ? 708 GLY B N   1 
ATOM   11695 C  CA  . GLY B 1 708 ? 206.884 222.474 164.967 1.00 81.99  ? 708 GLY B CA  1 
ATOM   11696 C  C   . GLY B 1 708 ? 206.093 221.606 165.922 1.00 81.12  ? 708 GLY B C   1 
ATOM   11697 O  O   . GLY B 1 708 ? 204.943 221.911 166.252 1.00 79.63  ? 708 GLY B O   1 
ATOM   11698 N  N   . THR B 1 709 ? 206.722 220.521 166.380 1.00 80.39  ? 709 THR B N   1 
ATOM   11699 C  CA  . THR B 1 709 ? 206.081 219.443 167.143 1.00 79.74  ? 709 THR B CA  1 
ATOM   11700 C  C   . THR B 1 709 ? 204.960 218.767 166.355 1.00 78.05  ? 709 THR B C   1 
ATOM   11701 O  O   . THR B 1 709 ? 203.974 218.306 166.931 1.00 77.62  ? 709 THR B O   1 
ATOM   11702 C  CB  . THR B 1 709 ? 205.560 219.913 168.510 1.00 80.70  ? 709 THR B CB  1 
ATOM   11703 O  OG1 . THR B 1 709 ? 204.886 221.172 168.390 1.00 83.60  ? 709 THR B OG1 1 
ATOM   11704 C  CG2 . THR B 1 709 ? 206.710 220.053 169.496 1.00 84.53  ? 709 THR B CG2 1 
ATOM   11705 N  N   . GLY B 1 710 ? 205.103 218.700 165.035 1.00 76.42  ? 710 GLY B N   1 
ATOM   11706 C  CA  . GLY B 1 710 ? 204.243 217.866 164.217 1.00 74.08  ? 710 GLY B CA  1 
ATOM   11707 C  C   . GLY B 1 710 ? 202.871 218.442 163.911 1.00 70.79  ? 710 GLY B C   1 
ATOM   11708 O  O   . GLY B 1 710 ? 202.608 219.654 163.996 1.00 74.99  ? 710 GLY B O   1 
ATOM   11709 N  N   . PHE B 1 711 ? 201.974 217.528 163.534 1.00 64.48  ? 711 PHE B N   1 
ATOM   11710 C  CA  . PHE B 1 711 ? 200.646 217.932 163.094 1.00 65.71  ? 711 PHE B CA  1 
ATOM   11711 C  C   . PHE B 1 711 ? 199.852 218.590 164.210 1.00 69.56  ? 711 PHE B C   1 
ATOM   11712 O  O   . PHE B 1 711 ? 199.011 219.451 163.941 1.00 71.90  ? 711 PHE B O   1 
ATOM   11713 C  CB  . PHE B 1 711 ? 199.882 216.732 162.547 1.00 69.03  ? 711 PHE B CB  1 
ATOM   11714 C  CG  . PHE B 1 711 ? 200.163 216.444 161.108 1.00 70.50  ? 711 PHE B CG  1 
ATOM   11715 C  CD1 . PHE B 1 711 ? 200.805 217.374 160.316 1.00 69.76  ? 711 PHE B CD1 1 
ATOM   11716 C  CD2 . PHE B 1 711 ? 199.776 215.246 160.542 1.00 65.98  ? 711 PHE B CD2 1 
ATOM   11717 C  CE1 . PHE B 1 711 ? 201.056 217.112 158.994 1.00 68.11  ? 711 PHE B CE1 1 
ATOM   11718 C  CE2 . PHE B 1 711 ? 200.028 214.981 159.222 1.00 61.90  ? 711 PHE B CE2 1 
ATOM   11719 C  CZ  . PHE B 1 711 ? 200.669 215.916 158.447 1.00 64.68  ? 711 PHE B CZ  1 
ATOM   11720 N  N   . SER B 1 712 ? 200.091 218.204 165.462 1.00 69.44  ? 712 SER B N   1 
ATOM   11721 C  CA  . SER B 1 712 ? 199.433 218.895 166.564 1.00 73.92  ? 712 SER B CA  1 
ATOM   11722 C  C   . SER B 1 712 ? 199.846 220.360 166.607 1.00 72.94  ? 712 SER B C   1 
ATOM   11723 O  O   . SER B 1 712 ? 199.001 221.252 166.767 1.00 74.60  ? 712 SER B O   1 
ATOM   11724 C  CB  . SER B 1 712 ? 199.759 218.204 167.887 1.00 76.66  ? 712 SER B CB  1 
ATOM   11725 O  OG  . SER B 1 712 ? 201.149 217.954 168.001 1.00 75.76  ? 712 SER B OG  1 
ATOM   11726 N  N   . GLY B 1 713 ? 201.141 220.626 166.456 1.00 73.40  ? 713 GLY B N   1 
ATOM   11727 C  CA  . GLY B 1 713 ? 201.598 222.001 166.419 1.00 74.32  ? 713 GLY B CA  1 
ATOM   11728 C  C   . GLY B 1 713 ? 201.016 222.765 165.251 1.00 70.04  ? 713 GLY B C   1 
ATOM   11729 O  O   . GLY B 1 713 ? 200.641 223.932 165.384 1.00 75.10  ? 713 GLY B O   1 
ATOM   11730 N  N   . LEU B 1 714 ? 200.919 222.117 164.093 1.00 64.38  ? 714 LEU B N   1 
ATOM   11731 C  CA  . LEU B 1 714 ? 200.322 222.787 162.944 1.00 66.44  ? 714 LEU B CA  1 
ATOM   11732 C  C   . LEU B 1 714 ? 198.852 223.098 163.186 1.00 67.04  ? 714 LEU B C   1 
ATOM   11733 O  O   . LEU B 1 714 ? 198.351 224.153 162.772 1.00 69.73  ? 714 LEU B O   1 
ATOM   11734 C  CB  . LEU B 1 714 ? 200.488 221.933 161.696 1.00 73.72  ? 714 LEU B CB  1 
ATOM   11735 C  CG  . LEU B 1 714 ? 201.461 222.537 160.695 1.00 75.34  ? 714 LEU B CG  1 
ATOM   11736 C  CD1 . LEU B 1 714 ? 201.492 221.697 159.447 1.00 72.16  ? 714 LEU B CD1 1 
ATOM   11737 C  CD2 . LEU B 1 714 ? 201.066 223.965 160.382 1.00 77.12  ? 714 LEU B CD2 1 
ATOM   11738 N  N   . SER B 1 715 ? 198.139 222.181 163.834 1.00 65.97  ? 715 SER B N   1 
ATOM   11739 C  CA  . SER B 1 715 ? 196.742 222.428 164.153 1.00 70.21  ? 715 SER B CA  1 
ATOM   11740 C  C   . SER B 1 715 ? 196.606 223.613 165.092 1.00 73.94  ? 715 SER B C   1 
ATOM   11741 O  O   . SER B 1 715 ? 195.713 224.451 164.924 1.00 73.39  ? 715 SER B O   1 
ATOM   11742 C  CB  . SER B 1 715 ? 196.116 221.180 164.771 1.00 74.36  ? 715 SER B CB  1 
ATOM   11743 O  OG  . SER B 1 715 ? 196.802 220.802 165.951 1.00 77.47  ? 715 SER B OG  1 
ATOM   11744 N  N   . ARG B 1 716 ? 197.491 223.705 166.087 1.00 73.84  ? 716 ARG B N   1 
ATOM   11745 C  CA  . ARG B 1 716 ? 197.468 224.864 166.973 1.00 69.32  ? 716 ARG B CA  1 
ATOM   11746 C  C   . ARG B 1 716 ? 197.747 226.138 166.195 1.00 64.03  ? 716 ARG B C   1 
ATOM   11747 O  O   . ARG B 1 716 ? 197.131 227.178 166.444 1.00 62.85  ? 716 ARG B O   1 
ATOM   11748 C  CB  . ARG B 1 716 ? 198.489 224.697 168.095 1.00 70.85  ? 716 ARG B CB  1 
ATOM   11749 C  CG  . ARG B 1 716 ? 198.316 223.438 168.935 1.00 80.62  ? 716 ARG B CG  1 
ATOM   11750 C  CD  . ARG B 1 716 ? 197.237 223.574 170.005 1.00 94.27  ? 716 ARG B CD  1 
ATOM   11751 N  NE  . ARG B 1 716 ? 195.895 223.644 169.437 1.00 96.59  ? 716 ARG B NE  1 
ATOM   11752 C  CZ  . ARG B 1 716 ? 194.777 223.435 170.119 1.00 103.34 ? 716 ARG B CZ  1 
ATOM   11753 N  NH1 . ARG B 1 716 ? 194.799 223.129 171.406 1.00 108.97 ? 716 ARG B NH1 1 
ATOM   11754 N  NH2 . ARG B 1 716 ? 193.608 223.533 169.493 1.00 96.93  ? 716 ARG B NH2 1 
ATOM   11755 N  N   . LEU B 1 717 ? 198.670 226.064 165.239 1.00 66.21  ? 717 LEU B N   1 
ATOM   11756 C  CA  . LEU B 1 717 ? 199.034 227.224 164.435 1.00 67.10  ? 717 LEU B CA  1 
ATOM   11757 C  C   . LEU B 1 717 ? 197.846 227.746 163.644 1.00 68.76  ? 717 LEU B C   1 
ATOM   11758 O  O   . LEU B 1 717 ? 197.551 228.945 163.659 1.00 70.27  ? 717 LEU B O   1 
ATOM   11759 C  CB  . LEU B 1 717 ? 200.167 226.839 163.494 1.00 66.64  ? 717 LEU B CB  1 
ATOM   11760 C  CG  . LEU B 1 717 ? 201.558 227.309 163.883 1.00 67.45  ? 717 LEU B CG  1 
ATOM   11761 C  CD1 . LEU B 1 717 ? 201.725 228.784 163.649 1.00 64.30  ? 717 LEU B CD1 1 
ATOM   11762 C  CD2 . LEU B 1 717 ? 201.834 226.976 165.343 1.00 68.67  ? 717 LEU B CD2 1 
ATOM   11763 N  N   . VAL B 1 718 ? 197.159 226.856 162.932 1.00 67.56  ? 718 VAL B N   1 
ATOM   11764 C  CA  . VAL B 1 718 ? 196.029 227.290 162.116 1.00 62.81  ? 718 VAL B CA  1 
ATOM   11765 C  C   . VAL B 1 718 ? 194.858 227.711 162.997 1.00 59.89  ? 718 VAL B C   1 
ATOM   11766 O  O   . VAL B 1 718 ? 194.143 228.667 162.683 1.00 59.50  ? 718 VAL B O   1 
ATOM   11767 C  CB  . VAL B 1 718 ? 195.637 226.186 161.121 1.00 67.86  ? 718 VAL B CB  1 
ATOM   11768 C  CG1 . VAL B 1 718 ? 194.528 226.666 160.206 1.00 68.47  ? 718 VAL B CG1 1 
ATOM   11769 C  CG2 . VAL B 1 718 ? 196.847 225.769 160.309 1.00 67.84  ? 718 VAL B CG2 1 
ATOM   11770 N  N   . SER B 1 719 ? 194.638 227.005 164.107 1.00 59.52  ? 719 SER B N   1 
ATOM   11771 C  CA  . SER B 1 719 ? 193.545 227.359 165.007 1.00 62.75  ? 719 SER B CA  1 
ATOM   11772 C  C   . SER B 1 719 ? 193.806 228.674 165.729 1.00 69.80  ? 719 SER B C   1 
ATOM   11773 O  O   . SER B 1 719 ? 192.858 229.388 166.074 1.00 71.01  ? 719 SER B O   1 
ATOM   11774 C  CB  . SER B 1 719 ? 193.316 226.239 166.019 1.00 62.72  ? 719 SER B CB  1 
ATOM   11775 O  OG  . SER B 1 719 ? 192.225 226.543 166.870 1.00 63.10  ? 719 SER B OG  1 
ATOM   11776 N  N   . LEU B 1 720 ? 195.071 228.997 165.985 1.00 70.30  ? 720 LEU B N   1 
ATOM   11777 C  CA  . LEU B 1 720 ? 195.468 230.279 166.555 1.00 62.92  ? 720 LEU B CA  1 
ATOM   11778 C  C   . LEU B 1 720 ? 196.051 231.133 165.443 1.00 55.60  ? 720 LEU B C   1 
ATOM   11779 O  O   . LEU B 1 720 ? 197.269 231.133 165.247 1.00 57.57  ? 720 LEU B O   1 
ATOM   11780 C  CB  . LEU B 1 720 ? 196.494 230.088 167.672 1.00 67.59  ? 720 LEU B CB  1 
ATOM   11781 C  CG  . LEU B 1 720 ? 197.055 231.332 168.359 1.00 67.61  ? 720 LEU B CG  1 
ATOM   11782 C  CD1 . LEU B 1 720 ? 195.976 232.055 169.151 1.00 74.91  ? 720 LEU B CD1 1 
ATOM   11783 C  CD2 . LEU B 1 720 ? 198.229 230.955 169.250 1.00 71.37  ? 720 LEU B CD2 1 
ATOM   11784 N  N   . PRO B 1 721 ? 195.227 231.859 164.702 1.00 50.27  ? 721 PRO B N   1 
ATOM   11785 C  CA  . PRO B 1 721 ? 195.724 232.555 163.510 1.00 51.25  ? 721 PRO B CA  1 
ATOM   11786 C  C   . PRO B 1 721 ? 196.957 233.397 163.791 1.00 53.02  ? 721 PRO B C   1 
ATOM   11787 O  O   . PRO B 1 721 ? 196.896 234.363 164.555 1.00 60.12  ? 721 PRO B O   1 
ATOM   11788 C  CB  . PRO B 1 721 ? 194.534 233.428 163.092 1.00 50.20  ? 721 PRO B CB  1 
ATOM   11789 C  CG  . PRO B 1 721 ? 193.351 232.789 163.695 1.00 48.59  ? 721 PRO B CG  1 
ATOM   11790 C  CD  . PRO B 1 721 ? 193.805 232.131 164.958 1.00 50.81  ? 721 PRO B CD  1 
ATOM   11791 N  N   . VAL B 1 722 ? 198.086 233.029 163.188 1.00 48.64  ? 722 VAL B N   1 
ATOM   11792 C  CA  . VAL B 1 722 ? 199.331 233.726 163.478 1.00 48.02  ? 722 VAL B CA  1 
ATOM   11793 C  C   . VAL B 1 722 ? 199.588 234.853 162.488 1.00 47.95  ? 722 VAL B C   1 
ATOM   11794 O  O   . VAL B 1 722 ? 200.209 235.857 162.843 1.00 52.22  ? 722 VAL B O   1 
ATOM   11795 C  CB  . VAL B 1 722 ? 200.505 232.736 163.523 1.00 47.52  ? 722 VAL B CB  1 
ATOM   11796 C  CG1 . VAL B 1 722 ? 200.266 231.728 164.594 1.00 52.63  ? 722 VAL B CG1 1 
ATOM   11797 C  CG2 . VAL B 1 722 ? 200.672 232.036 162.192 1.00 46.04  ? 722 VAL B CG2 1 
ATOM   11798 N  N   . THR B 1 723 ? 199.145 234.707 161.245 1.00 49.29  ? 723 THR B N   1 
ATOM   11799 C  CA  . THR B 1 723 ? 199.177 235.767 160.242 1.00 50.83  ? 723 THR B CA  1 
ATOM   11800 C  C   . THR B 1 723 ? 200.577 236.251 159.876 1.00 43.56  ? 723 THR B C   1 
ATOM   11801 O  O   . THR B 1 723 ? 200.712 237.166 159.061 1.00 46.14  ? 723 THR B O   1 
ATOM   11802 C  CB  . THR B 1 723 ? 198.330 236.958 160.703 1.00 57.53  ? 723 THR B CB  1 
ATOM   11803 O  OG1 . THR B 1 723 ? 199.016 237.665 161.743 1.00 57.71  ? 723 THR B OG1 1 
ATOM   11804 C  CG2 . THR B 1 723 ? 196.975 236.488 161.221 1.00 54.96  ? 723 THR B CG2 1 
ATOM   11805 N  N   . GLU B 1 724 ? 201.617 235.653 160.445 1.00 41.95  ? 724 GLU B N   1 
ATOM   11806 C  CA  . GLU B 1 724 ? 202.980 236.034 160.103 1.00 44.54  ? 724 GLU B CA  1 
ATOM   11807 C  C   . GLU B 1 724 ? 203.950 235.050 160.738 1.00 42.59  ? 724 GLU B C   1 
ATOM   11808 O  O   . GLU B 1 724 ? 203.823 234.713 161.917 1.00 46.83  ? 724 GLU B O   1 
ATOM   11809 C  CB  . GLU B 1 724 ? 203.294 237.461 160.569 1.00 46.81  ? 724 GLU B CB  1 
ATOM   11810 C  CG  . GLU B 1 724 ? 204.777 237.780 160.660 1.00 48.69  ? 724 GLU B CG  1 
ATOM   11811 C  CD  . GLU B 1 724 ? 205.059 239.036 161.456 1.00 56.10  ? 724 GLU B CD  1 
ATOM   11812 O  OE1 . GLU B 1 724 ? 204.135 239.860 161.615 1.00 60.10  ? 724 GLU B OE1 1 
ATOM   11813 O  OE2 . GLU B 1 724 ? 206.205 239.202 161.921 1.00 58.28  ? 724 GLU B OE2 1 
ATOM   11814 N  N   . ILE B 1 725 ? 204.921 234.603 159.953 1.00 35.95  ? 725 ILE B N   1 
ATOM   11815 C  CA  . ILE B 1 725 ? 205.965 233.710 160.425 1.00 32.98  ? 725 ILE B CA  1 
ATOM   11816 C  C   . ILE B 1 725 ? 207.297 234.410 160.248 1.00 40.39  ? 725 ILE B C   1 
ATOM   11817 O  O   . ILE B 1 725 ? 207.552 235.018 159.204 1.00 48.68  ? 725 ILE B O   1 
ATOM   11818 C  CB  . ILE B 1 725 ? 205.958 232.368 159.671 1.00 37.34  ? 725 ILE B CB  1 
ATOM   11819 C  CG1 . ILE B 1 725 ? 204.641 231.631 159.903 1.00 50.94  ? 725 ILE B CG1 1 
ATOM   11820 C  CG2 . ILE B 1 725 ? 207.135 231.516 160.073 1.00 42.50  ? 725 ILE B CG2 1 
ATOM   11821 C  CD1 . ILE B 1 725 ? 204.724 230.139 159.641 1.00 60.12  ? 725 ILE B CD1 1 
ATOM   11822 N  N   . LYS B 1 726 ? 208.144 234.328 161.268 1.00 42.37  ? 726 LYS B N   1 
ATOM   11823 C  CA  . LYS B 1 726 ? 209.458 234.948 161.241 1.00 42.32  ? 726 LYS B CA  1 
ATOM   11824 C  C   . LYS B 1 726 ? 210.522 233.905 160.957 1.00 38.06  ? 726 LYS B C   1 
ATOM   11825 O  O   . LYS B 1 726 ? 210.440 232.775 161.442 1.00 42.79  ? 726 LYS B O   1 
ATOM   11826 C  CB  . LYS B 1 726 ? 209.763 235.637 162.568 1.00 43.05  ? 726 LYS B CB  1 
ATOM   11827 C  CG  . LYS B 1 726 ? 210.980 236.528 162.521 1.00 50.44  ? 726 LYS B CG  1 
ATOM   11828 C  CD  . LYS B 1 726 ? 210.565 237.979 162.446 1.00 52.36  ? 726 LYS B CD  1 
ATOM   11829 C  CE  . LYS B 1 726 ? 210.037 238.433 163.780 1.00 53.48  ? 726 LYS B CE  1 
ATOM   11830 N  NZ  . LYS B 1 726 ? 209.483 239.810 163.739 1.00 55.84  ? 726 LYS B NZ  1 
ATOM   11831 N  N   . ILE B 1 727 ? 211.516 234.282 160.163 1.00 37.68  ? 727 ILE B N   1 
ATOM   11832 C  CA  . ILE B 1 727 ? 212.670 233.434 159.899 1.00 41.46  ? 727 ILE B CA  1 
ATOM   11833 C  C   . ILE B 1 727 ? 213.853 234.015 160.654 1.00 56.21  ? 727 ILE B C   1 
ATOM   11834 O  O   . ILE B 1 727 ? 214.207 235.184 160.463 1.00 64.36  ? 727 ILE B O   1 
ATOM   11835 C  CB  . ILE B 1 727 ? 212.970 233.335 158.402 1.00 39.76  ? 727 ILE B CB  1 
ATOM   11836 C  CG1 . ILE B 1 727 ? 211.682 233.076 157.640 1.00 43.37  ? 727 ILE B CG1 1 
ATOM   11837 C  CG2 . ILE B 1 727 ? 213.977 232.252 158.140 1.00 49.72  ? 727 ILE B CG2 1 
ATOM   11838 C  CD1 . ILE B 1 727 ? 211.743 233.513 156.211 1.00 50.70  ? 727 ILE B CD1 1 
ATOM   11839 N  N   . ASP B 1 728 ? 214.468 233.200 161.499 1.00 61.02  ? 728 ASP B N   1 
ATOM   11840 C  CA  . ASP B 1 728 ? 215.517 233.680 162.381 1.00 69.35  ? 728 ASP B CA  1 
ATOM   11841 C  C   . ASP B 1 728 ? 216.739 234.093 161.565 1.00 74.55  ? 728 ASP B C   1 
ATOM   11842 O  O   . ASP B 1 728 ? 216.900 233.710 160.405 1.00 75.41  ? 728 ASP B O   1 
ATOM   11843 C  CB  . ASP B 1 728 ? 215.860 232.596 163.409 1.00 77.51  ? 728 ASP B CB  1 
ATOM   11844 C  CG  . ASP B 1 728 ? 217.199 232.814 164.081 1.00 86.09  ? 728 ASP B CG  1 
ATOM   11845 O  OD1 . ASP B 1 728 ? 218.191 232.206 163.637 1.00 90.17  ? 728 ASP B OD1 1 
ATOM   11846 O  OD2 . ASP B 1 728 ? 217.257 233.592 165.057 1.00 84.52  ? 728 ASP B OD2 1 
ATOM   11847 N  N   . LYS B 1 729 ? 217.594 234.912 162.180 1.00 76.84  ? 729 LYS B N   1 
ATOM   11848 C  CA  . LYS B 1 729 ? 218.752 235.449 161.473 1.00 77.24  ? 729 LYS B CA  1 
ATOM   11849 C  C   . LYS B 1 729 ? 219.663 234.346 160.952 1.00 78.18  ? 729 LYS B C   1 
ATOM   11850 O  O   . LYS B 1 729 ? 220.289 234.508 159.899 1.00 82.07  ? 729 LYS B O   1 
ATOM   11851 C  CB  . LYS B 1 729 ? 219.524 236.396 162.393 1.00 82.25  ? 729 LYS B CB  1 
ATOM   11852 C  CG  . LYS B 1 729 ? 220.955 236.697 161.968 1.00 85.99  ? 729 LYS B CG  1 
ATOM   11853 C  CD  . LYS B 1 729 ? 221.887 236.796 163.168 1.00 90.16  ? 729 LYS B CD  1 
ATOM   11854 C  CE  . LYS B 1 729 ? 222.264 235.426 163.705 1.00 90.28  ? 729 LYS B CE  1 
ATOM   11855 N  NZ  . LYS B 1 729 ? 222.510 234.458 162.604 1.00 84.58  ? 729 LYS B NZ  1 
ATOM   11856 N  N   . SER B 1 730 ? 219.740 233.216 161.655 1.00 76.61  ? 730 SER B N   1 
ATOM   11857 C  CA  . SER B 1 730 ? 220.638 232.149 161.224 1.00 78.17  ? 730 SER B CA  1 
ATOM   11858 C  C   . SER B 1 730 ? 220.210 231.556 159.890 1.00 79.97  ? 730 SER B C   1 
ATOM   11859 O  O   . SER B 1 730 ? 221.048 231.327 159.014 1.00 81.77  ? 730 SER B O   1 
ATOM   11860 C  CB  . SER B 1 730 ? 220.713 231.058 162.288 1.00 81.22  ? 730 SER B CB  1 
ATOM   11861 O  OG  . SER B 1 730 ? 219.423 230.557 162.587 1.00 83.46  ? 730 SER B OG  1 
ATOM   11862 N  N   . PHE B 1 731 ? 218.916 231.288 159.717 1.00 80.61  ? 731 PHE B N   1 
ATOM   11863 C  CA  . PHE B 1 731 ? 218.467 230.650 158.485 1.00 80.19  ? 731 PHE B CA  1 
ATOM   11864 C  C   . PHE B 1 731 ? 218.695 231.554 157.284 1.00 82.02  ? 731 PHE B C   1 
ATOM   11865 O  O   . PHE B 1 731 ? 219.148 231.091 156.231 1.00 85.39  ? 731 PHE B O   1 
ATOM   11866 C  CB  . PHE B 1 731 ? 216.994 230.265 158.589 1.00 78.90  ? 731 PHE B CB  1 
ATOM   11867 C  CG  . PHE B 1 731 ? 216.709 229.238 159.641 1.00 76.39  ? 731 PHE B CG  1 
ATOM   11868 C  CD1 . PHE B 1 731 ? 217.688 228.353 160.050 1.00 79.86  ? 731 PHE B CD1 1 
ATOM   11869 C  CD2 . PHE B 1 731 ? 215.462 229.160 160.222 1.00 74.73  ? 731 PHE B CD2 1 
ATOM   11870 C  CE1 . PHE B 1 731 ? 217.423 227.411 161.021 1.00 85.18  ? 731 PHE B CE1 1 
ATOM   11871 C  CE2 . PHE B 1 731 ? 215.194 228.225 161.189 1.00 77.41  ? 731 PHE B CE2 1 
ATOM   11872 C  CZ  . PHE B 1 731 ? 216.173 227.348 161.590 1.00 81.87  ? 731 PHE B CZ  1 
ATOM   11873 N  N   . VAL B 1 732 ? 218.384 232.845 157.419 1.00 79.69  ? 732 VAL B N   1 
ATOM   11874 C  CA  . VAL B 1 732 ? 218.661 233.784 156.340 1.00 75.86  ? 732 VAL B CA  1 
ATOM   11875 C  C   . VAL B 1 732 ? 220.155 233.888 156.118 1.00 77.67  ? 732 VAL B C   1 
ATOM   11876 O  O   . VAL B 1 732 ? 220.613 234.059 154.984 1.00 84.08  ? 732 VAL B O   1 
ATOM   11877 C  CB  . VAL B 1 732 ? 218.036 235.157 156.640 1.00 72.30  ? 732 VAL B CB  1 
ATOM   11878 C  CG1 . VAL B 1 732 ? 218.344 236.127 155.529 1.00 72.86  ? 732 VAL B CG1 1 
ATOM   11879 C  CG2 . VAL B 1 732 ? 216.537 235.023 156.819 1.00 71.79  ? 732 VAL B CG2 1 
ATOM   11880 N  N   . ASP B 1 733 ? 220.940 233.789 157.183 1.00 79.29  ? 733 ASP B N   1 
ATOM   11881 C  CA  . ASP B 1 733 ? 222.378 233.669 157.018 1.00 86.82  ? 733 ASP B CA  1 
ATOM   11882 C  C   . ASP B 1 733 ? 222.703 232.345 156.335 1.00 89.36  ? 733 ASP B C   1 
ATOM   11883 O  O   . ASP B 1 733 ? 221.985 231.353 156.481 1.00 91.27  ? 733 ASP B O   1 
ATOM   11884 C  CB  . ASP B 1 733 ? 223.088 233.765 158.368 1.00 91.82  ? 733 ASP B CB  1 
ATOM   11885 C  CG  . ASP B 1 733 ? 224.457 234.407 158.263 1.00 95.81  ? 733 ASP B CG  1 
ATOM   11886 O  OD1 . ASP B 1 733 ? 224.777 234.957 157.189 1.00 97.38  ? 733 ASP B OD1 1 
ATOM   11887 O  OD2 . ASP B 1 733 ? 225.215 234.362 159.255 1.00 93.71  ? 733 ASP B OD2 1 
ATOM   11888 N  N   . ARG B 1 734 ? 223.778 232.347 155.556 1.00 90.44  ? 734 ARG B N   1 
ATOM   11889 C  CA  . ARG B 1 734 ? 224.216 231.205 154.760 1.00 92.99  ? 734 ARG B CA  1 
ATOM   11890 C  C   . ARG B 1 734 ? 223.170 230.751 153.748 1.00 93.10  ? 734 ARG B C   1 
ATOM   11891 O  O   . ARG B 1 734 ? 223.326 229.682 153.146 1.00 95.86  ? 734 ARG B O   1 
ATOM   11892 C  CB  . ARG B 1 734 ? 224.618 230.015 155.642 1.00 92.45  ? 734 ARG B CB  1 
ATOM   11893 C  CG  . ARG B 1 734 ? 225.488 230.368 156.830 1.00 87.58  ? 734 ARG B CG  1 
ATOM   11894 C  CD  . ARG B 1 734 ? 225.863 229.116 157.604 1.00 90.05  ? 734 ARG B CD  1 
ATOM   11895 N  NE  . ARG B 1 734 ? 224.734 228.202 157.731 1.00 93.77  ? 734 ARG B NE  1 
ATOM   11896 C  CZ  . ARG B 1 734 ? 223.726 228.365 158.576 1.00 90.27  ? 734 ARG B CZ  1 
ATOM   11897 N  NH1 . ARG B 1 734 ? 223.673 229.400 159.397 1.00 84.24  ? 734 ARG B NH1 1 
ATOM   11898 N  NH2 . ARG B 1 734 ? 222.746 227.467 158.596 1.00 89.38  ? 734 ARG B NH2 1 
ATOM   11899 N  N   . CYS B 1 735 ? 222.116 231.541 153.530 1.00 90.44  ? 735 CYS B N   1 
ATOM   11900 C  CA  . CYS B 1 735 ? 221.090 231.150 152.572 1.00 93.57  ? 735 CYS B CA  1 
ATOM   11901 C  C   . CYS B 1 735 ? 221.671 230.950 151.181 1.00 100.25 ? 735 CYS B C   1 
ATOM   11902 O  O   . CYS B 1 735 ? 221.162 230.133 150.406 1.00 98.70  ? 735 CYS B O   1 
ATOM   11903 C  CB  . CYS B 1 735 ? 219.983 232.198 152.528 1.00 93.21  ? 735 CYS B CB  1 
ATOM   11904 S  SG  . CYS B 1 735 ? 220.498 233.777 151.821 1.00 105.44 ? 735 CYS B SG  1 
ATOM   11905 N  N   . LEU B 1 736 ? 222.735 231.675 150.851 1.00 103.30 ? 736 LEU B N   1 
ATOM   11906 C  CA  . LEU B 1 736 ? 223.428 231.528 149.580 1.00 103.40 ? 736 LEU B CA  1 
ATOM   11907 C  C   . LEU B 1 736 ? 224.577 230.531 149.644 1.00 104.67 ? 736 LEU B C   1 
ATOM   11908 O  O   . LEU B 1 736 ? 225.297 230.374 148.654 1.00 109.25 ? 736 LEU B O   1 
ATOM   11909 C  CB  . LEU B 1 736 ? 223.948 232.889 149.111 1.00 96.22  ? 736 LEU B CB  1 
ATOM   11910 C  CG  . LEU B 1 736 ? 222.865 233.921 148.799 1.00 89.30  ? 736 LEU B CG  1 
ATOM   11911 C  CD1 . LEU B 1 736 ? 223.273 235.302 149.280 1.00 85.18  ? 736 LEU B CD1 1 
ATOM   11912 C  CD2 . LEU B 1 736 ? 222.587 233.931 147.307 1.00 86.72  ? 736 LEU B CD2 1 
ATOM   11913 N  N   . THR B 1 737 ? 224.765 229.859 150.777 1.00 101.45 ? 737 THR B N   1 
ATOM   11914 C  CA  . THR B 1 737 ? 225.858 228.914 150.958 1.00 101.97 ? 737 THR B CA  1 
ATOM   11915 C  C   . THR B 1 737 ? 225.390 227.471 151.057 1.00 103.80 ? 737 THR B C   1 
ATOM   11916 O  O   . THR B 1 737 ? 225.867 226.615 150.307 1.00 103.30 ? 737 THR B O   1 
ATOM   11917 C  CB  . THR B 1 737 ? 226.666 229.281 152.210 1.00 102.34 ? 737 THR B CB  1 
ATOM   11918 O  OG1 . THR B 1 737 ? 227.112 230.639 152.111 1.00 98.62  ? 737 THR B OG1 1 
ATOM   11919 C  CG2 . THR B 1 737 ? 227.867 228.360 152.360 1.00 101.90 ? 737 THR B CG2 1 
ATOM   11920 N  N   . GLU B 1 738 ? 224.465 227.174 151.964 1.00 103.52 ? 738 GLU B N   1 
ATOM   11921 C  CA  . GLU B 1 738 ? 224.030 225.806 152.212 1.00 105.41 ? 738 GLU B CA  1 
ATOM   11922 C  C   . GLU B 1 738 ? 222.748 225.519 151.440 1.00 101.94 ? 738 GLU B C   1 
ATOM   11923 O  O   . GLU B 1 738 ? 221.787 226.291 151.512 1.00 101.16 ? 738 GLU B O   1 
ATOM   11924 C  CB  . GLU B 1 738 ? 223.817 225.564 153.707 1.00 103.43 ? 738 GLU B CB  1 
ATOM   11925 C  CG  . GLU B 1 738 ? 225.104 225.359 154.490 1.00 104.68 ? 738 GLU B CG  1 
ATOM   11926 C  CD  . GLU B 1 738 ? 224.899 224.531 155.742 1.00 109.74 ? 738 GLU B CD  1 
ATOM   11927 O  OE1 . GLU B 1 738 ? 224.669 223.309 155.618 1.00 109.65 ? 738 GLU B OE1 1 
ATOM   11928 O  OE2 . GLU B 1 738 ? 224.967 225.101 156.852 1.00 112.55 ? 738 GLU B OE2 1 
ATOM   11929 N  N   . LYS B 1 739 ? 222.741 224.404 150.706 1.00 99.85  ? 739 LYS B N   1 
ATOM   11930 C  CA  . LYS B 1 739 ? 221.577 224.055 149.900 1.00 99.99  ? 739 LYS B CA  1 
ATOM   11931 C  C   . LYS B 1 739 ? 220.420 223.570 150.758 1.00 94.84  ? 739 LYS B C   1 
ATOM   11932 O  O   . LYS B 1 739 ? 219.256 223.814 150.421 1.00 92.65  ? 739 LYS B O   1 
ATOM   11933 C  CB  . LYS B 1 739 ? 221.955 222.991 148.870 1.00 104.31 ? 739 LYS B CB  1 
ATOM   11934 C  CG  . LYS B 1 739 ? 220.824 222.604 147.930 1.00 105.11 ? 739 LYS B CG  1 
ATOM   11935 C  CD  . LYS B 1 739 ? 220.392 223.774 147.065 1.00 107.01 ? 739 LYS B CD  1 
ATOM   11936 C  CE  . LYS B 1 739 ? 219.380 223.335 146.020 1.00 106.62 ? 739 LYS B CE  1 
ATOM   11937 N  NZ  . LYS B 1 739 ? 219.004 224.450 145.108 1.00 99.27  ? 739 LYS B NZ  1 
ATOM   11938 N  N   . ARG B 1 740 ? 220.714 222.878 151.858 1.00 93.25  ? 740 ARG B N   1 
ATOM   11939 C  CA  . ARG B 1 740 ? 219.649 222.353 152.703 1.00 93.99  ? 740 ARG B CA  1 
ATOM   11940 C  C   . ARG B 1 740 ? 218.809 223.481 153.284 1.00 91.39  ? 740 ARG B C   1 
ATOM   11941 O  O   . ARG B 1 740 ? 217.575 223.426 153.262 1.00 89.67  ? 740 ARG B O   1 
ATOM   11942 C  CB  . ARG B 1 740 ? 220.244 221.487 153.813 1.00 100.92 ? 740 ARG B CB  1 
ATOM   11943 C  CG  . ARG B 1 740 ? 221.641 221.909 154.237 1.00 103.02 ? 740 ARG B CG  1 
ATOM   11944 C  CD  . ARG B 1 740 ? 222.170 221.046 155.373 1.00 109.57 ? 740 ARG B CD  1 
ATOM   11945 N  NE  . ARG B 1 740 ? 221.136 220.708 156.343 1.00 113.60 ? 740 ARG B NE  1 
ATOM   11946 C  CZ  . ARG B 1 740 ? 220.774 221.485 157.354 1.00 114.04 ? 740 ARG B CZ  1 
ATOM   11947 N  NH1 . ARG B 1 740 ? 221.343 222.662 157.560 1.00 111.21 ? 740 ARG B NH1 1 
ATOM   11948 N  NH2 . ARG B 1 740 ? 219.818 221.072 158.181 1.00 114.23 ? 740 ARG B NH2 1 
ATOM   11949 N  N   . ILE B 1 741 ? 219.461 224.527 153.795 1.00 92.38  ? 741 ILE B N   1 
ATOM   11950 C  CA  . ILE B 1 741 ? 218.701 225.643 154.344 1.00 90.30  ? 741 ILE B CA  1 
ATOM   11951 C  C   . ILE B 1 741 ? 218.033 226.434 153.230 1.00 85.61  ? 741 ILE B C   1 
ATOM   11952 O  O   . ILE B 1 741 ? 216.980 227.048 153.439 1.00 82.44  ? 741 ILE B O   1 
ATOM   11953 C  CB  . ILE B 1 741 ? 219.594 226.530 155.229 1.00 94.61  ? 741 ILE B CB  1 
ATOM   11954 C  CG1 . ILE B 1 741 ? 220.620 227.290 154.394 1.00 98.85  ? 741 ILE B CG1 1 
ATOM   11955 C  CG2 . ILE B 1 741 ? 220.288 225.692 156.288 1.00 94.94  ? 741 ILE B CG2 1 
ATOM   11956 C  CD1 . ILE B 1 741 ? 221.639 228.018 155.236 1.00 96.41  ? 741 ILE B CD1 1 
ATOM   11957 N  N   . LEU B 1 742 ? 218.608 226.419 152.030 1.00 85.42  ? 742 LEU B N   1 
ATOM   11958 C  CA  . LEU B 1 742 ? 217.931 227.016 150.888 1.00 84.92  ? 742 LEU B CA  1 
ATOM   11959 C  C   . LEU B 1 742 ? 216.595 226.331 150.645 1.00 80.77  ? 742 LEU B C   1 
ATOM   11960 O  O   . LEU B 1 742 ? 215.544 226.980 150.593 1.00 78.70  ? 742 LEU B O   1 
ATOM   11961 C  CB  . LEU B 1 742 ? 218.830 226.928 149.652 1.00 91.25  ? 742 LEU B CB  1 
ATOM   11962 C  CG  . LEU B 1 742 ? 218.407 227.664 148.381 1.00 91.21  ? 742 LEU B CG  1 
ATOM   11963 C  CD1 . LEU B 1 742 ? 219.609 228.324 147.727 1.00 89.39  ? 742 LEU B CD1 1 
ATOM   11964 C  CD2 . LEU B 1 742 ? 217.746 226.699 147.410 1.00 89.48  ? 742 LEU B CD2 1 
ATOM   11965 N  N   . ALA B 1 743 ? 216.616 225.005 150.540 1.00 83.67  ? 743 ALA B N   1 
ATOM   11966 C  CA  . ALA B 1 743 ? 215.380 224.261 150.351 1.00 81.44  ? 743 ALA B CA  1 
ATOM   11967 C  C   . ALA B 1 743 ? 214.434 224.450 151.524 1.00 75.56  ? 743 ALA B C   1 
ATOM   11968 O  O   . ALA B 1 743 ? 213.215 224.473 151.337 1.00 75.27  ? 743 ALA B O   1 
ATOM   11969 C  CB  . ALA B 1 743 ? 215.682 222.778 150.146 1.00 87.34  ? 743 ALA B CB  1 
ATOM   11970 N  N   . LEU B 1 744 ? 214.972 224.586 152.736 1.00 76.07  ? 744 LEU B N   1 
ATOM   11971 C  CA  . LEU B 1 744 ? 214.123 224.848 153.891 1.00 73.28  ? 744 LEU B CA  1 
ATOM   11972 C  C   . LEU B 1 744 ? 213.385 226.167 153.727 1.00 73.13  ? 744 LEU B C   1 
ATOM   11973 O  O   . LEU B 1 744 ? 212.200 226.271 154.058 1.00 70.16  ? 744 LEU B O   1 
ATOM   11974 C  CB  . LEU B 1 744 ? 214.965 224.859 155.165 1.00 73.66  ? 744 LEU B CB  1 
ATOM   11975 C  CG  . LEU B 1 744 ? 214.311 225.087 156.530 1.00 73.98  ? 744 LEU B CG  1 
ATOM   11976 C  CD1 . LEU B 1 744 ? 212.892 224.539 156.592 1.00 73.92  ? 744 LEU B CD1 1 
ATOM   11977 C  CD2 . LEU B 1 744 ? 215.162 224.477 157.630 1.00 77.86  ? 744 LEU B CD2 1 
ATOM   11978 N  N   . LEU B 1 745 ? 214.077 227.192 153.227 1.00 77.45  ? 745 LEU B N   1 
ATOM   11979 C  CA  . LEU B 1 745 ? 213.428 228.481 153.016 1.00 74.94  ? 745 LEU B CA  1 
ATOM   11980 C  C   . LEU B 1 745 ? 212.383 228.398 151.910 1.00 69.72  ? 745 LEU B C   1 
ATOM   11981 O  O   . LEU B 1 745 ? 211.320 229.020 152.011 1.00 66.33  ? 745 LEU B O   1 
ATOM   11982 C  CB  . LEU B 1 745 ? 214.473 229.550 152.706 1.00 74.91  ? 745 LEU B CB  1 
ATOM   11983 C  CG  . LEU B 1 745 ? 214.873 230.414 153.902 1.00 73.73  ? 745 LEU B CG  1 
ATOM   11984 C  CD1 . LEU B 1 745 ? 213.654 231.067 154.498 1.00 67.06  ? 745 LEU B CD1 1 
ATOM   11985 C  CD2 . LEU B 1 745 ? 215.603 229.591 154.942 1.00 74.81  ? 745 LEU B CD2 1 
ATOM   11986 N  N   . GLU B 1 746 ? 212.670 227.649 150.840 1.00 70.11  ? 746 GLU B N   1 
ATOM   11987 C  CA  . GLU B 1 746 ? 211.623 227.385 149.851 1.00 68.33  ? 746 GLU B CA  1 
ATOM   11988 C  C   . GLU B 1 746 ? 210.415 226.728 150.496 1.00 63.47  ? 746 GLU B C   1 
ATOM   11989 O  O   . GLU B 1 746 ? 209.271 227.115 150.232 1.00 61.50  ? 746 GLU B O   1 
ATOM   11990 C  CB  . GLU B 1 746 ? 212.129 226.510 148.700 1.00 70.97  ? 746 GLU B CB  1 
ATOM   11991 C  CG  . GLU B 1 746 ? 213.600 226.585 148.366 1.00 77.12  ? 746 GLU B CG  1 
ATOM   11992 C  CD  . GLU B 1 746 ? 214.046 228.007 148.094 1.00 83.59  ? 746 GLU B CD  1 
ATOM   11993 O  OE1 . GLU B 1 746 ? 213.215 228.775 147.577 1.00 79.01  ? 746 GLU B OE1 1 
ATOM   11994 O  OE2 . GLU B 1 746 ? 215.212 228.357 148.368 1.00 89.44  ? 746 GLU B OE2 1 
ATOM   11995 N  N   . ALA B 1 747 ? 210.649 225.734 151.345 1.00 65.15  ? 747 ALA B N   1 
ATOM   11996 C  CA  . ALA B 1 747 ? 209.543 225.067 152.009 1.00 65.80  ? 747 ALA B CA  1 
ATOM   11997 C  C   . ALA B 1 747 ? 208.752 226.052 152.850 1.00 64.57  ? 747 ALA B C   1 
ATOM   11998 O  O   . ALA B 1 747 ? 207.519 226.068 152.810 1.00 64.64  ? 747 ALA B O   1 
ATOM   11999 C  CB  . ALA B 1 747 ? 210.068 223.923 152.873 1.00 71.06  ? 747 ALA B CB  1 
ATOM   12000 N  N   . ILE B 1 748 ? 209.450 226.888 153.616 1.00 61.02  ? 748 ILE B N   1 
ATOM   12001 C  CA  . ILE B 1 748 ? 208.768 227.791 154.534 1.00 58.60  ? 748 ILE B CA  1 
ATOM   12002 C  C   . ILE B 1 748 ? 207.947 228.814 153.767 1.00 59.55  ? 748 ILE B C   1 
ATOM   12003 O  O   . ILE B 1 748 ? 206.793 229.082 154.113 1.00 62.81  ? 748 ILE B O   1 
ATOM   12004 C  CB  . ILE B 1 748 ? 209.773 228.465 155.479 1.00 59.47  ? 748 ILE B CB  1 
ATOM   12005 C  CG1 . ILE B 1 748 ? 210.408 227.432 156.403 1.00 69.12  ? 748 ILE B CG1 1 
ATOM   12006 C  CG2 . ILE B 1 748 ? 209.078 229.511 156.315 1.00 55.93  ? 748 ILE B CG2 1 
ATOM   12007 C  CD1 . ILE B 1 748 ? 211.567 227.965 157.197 1.00 71.81  ? 748 ILE B CD1 1 
ATOM   12008 N  N   . THR B 1 749 ? 208.514 229.389 152.705 1.00 58.55  ? 749 THR B N   1 
ATOM   12009 C  CA  . THR B 1 749 ? 207.755 230.366 151.939 1.00 55.48  ? 749 THR B CA  1 
ATOM   12010 C  C   . THR B 1 749 ? 206.605 229.712 151.193 1.00 60.97  ? 749 THR B C   1 
ATOM   12011 O  O   . THR B 1 749 ? 205.555 230.338 151.020 1.00 60.72  ? 749 THR B O   1 
ATOM   12012 C  CB  . THR B 1 749 ? 208.653 231.128 150.970 1.00 59.41  ? 749 THR B CB  1 
ATOM   12013 O  OG1 . THR B 1 749 ? 207.885 232.153 150.328 1.00 62.51  ? 749 THR B OG1 1 
ATOM   12014 C  CG2 . THR B 1 749 ? 209.226 230.209 149.910 1.00 63.40  ? 749 THR B CG2 1 
ATOM   12015 N  N   . SER B 1 750 ? 206.758 228.449 150.778 1.00 64.31  ? 750 SER B N   1 
ATOM   12016 C  CA  . SER B 1 750 ? 205.666 227.753 150.106 1.00 61.18  ? 750 SER B CA  1 
ATOM   12017 C  C   . SER B 1 750 ? 204.514 227.481 151.061 1.00 54.30  ? 750 SER B C   1 
ATOM   12018 O  O   . SER B 1 750 ? 203.350 227.751 150.739 1.00 55.57  ? 750 SER B O   1 
ATOM   12019 C  CB  . SER B 1 750 ? 206.184 226.455 149.499 1.00 67.12  ? 750 SER B CB  1 
ATOM   12020 O  OG  . SER B 1 750 ? 207.393 226.684 148.799 1.00 74.06  ? 750 SER B OG  1 
ATOM   12021 N  N   . ILE B 1 751 ? 204.820 226.957 152.250 1.00 50.06  ? 751 ILE B N   1 
ATOM   12022 C  CA  . ILE B 1 751 ? 203.777 226.744 153.247 1.00 50.29  ? 751 ILE B CA  1 
ATOM   12023 C  C   . ILE B 1 751 ? 203.113 228.062 153.606 1.00 49.40  ? 751 ILE B C   1 
ATOM   12024 O  O   . ILE B 1 751 ? 201.888 228.135 153.751 1.00 49.43  ? 751 ILE B O   1 
ATOM   12025 C  CB  . ILE B 1 751 ? 204.336 226.057 154.504 1.00 55.39  ? 751 ILE B CB  1 
ATOM   12026 C  CG1 . ILE B 1 751 ? 205.175 224.837 154.153 1.00 59.16  ? 751 ILE B CG1 1 
ATOM   12027 C  CG2 . ILE B 1 751 ? 203.209 225.658 155.420 1.00 58.92  ? 751 ILE B CG2 1 
ATOM   12028 C  CD1 . ILE B 1 751 ? 204.486 223.872 153.227 1.00 60.29  ? 751 ILE B CD1 1 
ATOM   12029 N  N   . GLY B 1 752 ? 203.904 229.122 153.765 1.00 52.29  ? 752 GLY B N   1 
ATOM   12030 C  CA  . GLY B 1 752 ? 203.325 230.404 154.122 1.00 52.32  ? 752 GLY B CA  1 
ATOM   12031 C  C   . GLY B 1 752 ? 202.403 230.941 153.049 1.00 52.64  ? 752 GLY B C   1 
ATOM   12032 O  O   . GLY B 1 752 ? 201.308 231.425 153.339 1.00 53.30  ? 752 GLY B O   1 
ATOM   12033 N  N   . GLN B 1 753 ? 202.831 230.860 151.789 1.00 53.11  ? 753 GLN B N   1 
ATOM   12034 C  CA  . GLN B 1 753 ? 202.004 231.364 150.704 1.00 53.94  ? 753 GLN B CA  1 
ATOM   12035 C  C   . GLN B 1 753 ? 200.717 230.557 150.609 1.00 58.24  ? 753 GLN B C   1 
ATOM   12036 O  O   . GLN B 1 753 ? 199.640 231.114 150.374 1.00 60.40  ? 753 GLN B O   1 
ATOM   12037 C  CB  . GLN B 1 753 ? 202.787 231.304 149.395 1.00 57.51  ? 753 GLN B CB  1 
ATOM   12038 C  CG  . GLN B 1 753 ? 202.110 231.872 148.148 1.00 61.90  ? 753 GLN B CG  1 
ATOM   12039 C  CD  . GLN B 1 753 ? 201.219 233.077 148.415 1.00 67.40  ? 753 GLN B CD  1 
ATOM   12040 O  OE1 . GLN B 1 753 ? 201.661 234.224 148.382 1.00 67.50  ? 753 GLN B OE1 1 
ATOM   12041 N  NE2 . GLN B 1 753 ? 199.947 232.812 148.682 1.00 72.00  ? 753 GLN B NE2 1 
ATOM   12042 N  N   . SER B 1 754 ? 200.805 229.244 150.845 1.00 61.06  ? 754 SER B N   1 
ATOM   12043 C  CA  . SER B 1 754 ? 199.611 228.404 150.822 1.00 59.97  ? 754 SER B CA  1 
ATOM   12044 C  C   . SER B 1 754 ? 198.559 228.908 151.804 1.00 54.51  ? 754 SER B C   1 
ATOM   12045 O  O   . SER B 1 754 ? 197.393 229.090 151.443 1.00 56.70  ? 754 SER B O   1 
ATOM   12046 C  CB  . SER B 1 754 ? 199.989 226.965 151.148 1.00 59.23  ? 754 SER B CB  1 
ATOM   12047 O  OG  . SER B 1 754 ? 200.072 226.792 152.552 1.00 58.97  ? 754 SER B OG  1 
ATOM   12048 N  N   . LEU B 1 755 ? 198.957 229.160 153.042 1.00 47.84  ? 755 LEU B N   1 
ATOM   12049 C  CA  . LEU B 1 755 ? 198.034 229.670 154.042 1.00 46.58  ? 755 LEU B CA  1 
ATOM   12050 C  C   . LEU B 1 755 ? 197.972 231.191 153.935 1.00 53.46  ? 755 LEU B C   1 
ATOM   12051 O  O   . LEU B 1 755 ? 198.532 231.797 153.018 1.00 53.76  ? 755 LEU B O   1 
ATOM   12052 C  CB  . LEU B 1 755 ? 198.457 229.212 155.431 1.00 44.83  ? 755 LEU B CB  1 
ATOM   12053 C  CG  . LEU B 1 755 ? 198.450 227.710 155.677 1.00 39.64  ? 755 LEU B CG  1 
ATOM   12054 C  CD1 . LEU B 1 755 ? 199.211 227.368 156.939 1.00 35.22  ? 755 LEU B CD1 1 
ATOM   12055 C  CD2 . LEU B 1 755 ? 197.024 227.219 155.765 1.00 48.40  ? 755 LEU B CD2 1 
ATOM   12056 N  N   . ASN B 1 756 ? 197.278 231.825 154.876 1.00 55.59  ? 756 ASN B N   1 
ATOM   12057 C  CA  . ASN B 1 756 ? 197.126 233.281 154.915 1.00 54.80  ? 756 ASN B CA  1 
ATOM   12058 C  C   . ASN B 1 756 ? 198.163 233.959 155.811 1.00 57.57  ? 756 ASN B C   1 
ATOM   12059 O  O   . ASN B 1 756 ? 197.826 234.743 156.696 1.00 58.15  ? 756 ASN B O   1 
ATOM   12060 C  CB  . ASN B 1 756 ? 195.707 233.629 155.348 1.00 55.66  ? 756 ASN B CB  1 
ATOM   12061 C  CG  . ASN B 1 756 ? 195.331 233.013 156.687 1.00 60.55  ? 756 ASN B CG  1 
ATOM   12062 O  OD1 . ASN B 1 756 ? 196.141 232.940 157.609 1.00 52.06  ? 756 ASN B OD1 1 
ATOM   12063 N  ND2 . ASN B 1 756 ? 194.086 232.565 156.794 1.00 65.77  ? 756 ASN B ND2 1 
ATOM   12064 N  N   . LEU B 1 757 ? 199.444 233.690 155.569 1.00 58.52  ? 757 LEU B N   1 
ATOM   12065 C  CA  . LEU B 1 757 ? 200.521 234.209 156.398 1.00 54.44  ? 757 LEU B CA  1 
ATOM   12066 C  C   . LEU B 1 757 ? 201.487 235.041 155.566 1.00 55.54  ? 757 LEU B C   1 
ATOM   12067 O  O   . LEU B 1 757 ? 201.683 234.787 154.375 1.00 57.72  ? 757 LEU B O   1 
ATOM   12068 C  CB  . LEU B 1 757 ? 201.292 233.079 157.082 1.00 49.14  ? 757 LEU B CB  1 
ATOM   12069 C  CG  . LEU B 1 757 ? 200.481 231.972 157.745 1.00 49.72  ? 757 LEU B CG  1 
ATOM   12070 C  CD1 . LEU B 1 757 ? 201.401 231.020 158.471 1.00 43.45  ? 757 LEU B CD1 1 
ATOM   12071 C  CD2 . LEU B 1 757 ? 199.444 232.543 158.687 1.00 51.20  ? 757 LEU B CD2 1 
ATOM   12072 N  N   . THR B 1 758 ? 202.090 236.041 156.210 1.00 54.10  ? 758 THR B N   1 
ATOM   12073 C  CA  . THR B 1 758 ? 203.116 236.886 155.607 1.00 49.36  ? 758 THR B CA  1 
ATOM   12074 C  C   . THR B 1 758 ? 204.458 236.531 156.226 1.00 43.67  ? 758 THR B C   1 
ATOM   12075 O  O   . THR B 1 758 ? 204.635 236.650 157.441 1.00 46.62  ? 758 THR B O   1 
ATOM   12076 C  CB  . THR B 1 758 ? 202.809 238.364 155.824 1.00 51.12  ? 758 THR B CB  1 
ATOM   12077 O  OG1 . THR B 1 758 ? 201.638 238.723 155.083 1.00 56.77  ? 758 THR B OG1 1 
ATOM   12078 C  CG2 . THR B 1 758 ? 203.969 239.208 155.347 1.00 55.61  ? 758 THR B CG2 1 
ATOM   12079 N  N   . VAL B 1 759 ? 205.396 236.106 155.404 1.00 37.88  ? 759 VAL B N   1 
ATOM   12080 C  CA  . VAL B 1 759 ? 206.670 235.612 155.896 1.00 38.82  ? 759 VAL B CA  1 
ATOM   12081 C  C   . VAL B 1 759 ? 207.680 236.752 155.901 1.00 51.36  ? 759 VAL B C   1 
ATOM   12082 O  O   . VAL B 1 759 ? 207.807 237.491 154.917 1.00 57.14  ? 759 VAL B O   1 
ATOM   12083 C  CB  . VAL B 1 759 ? 207.166 234.435 155.050 1.00 33.05  ? 759 VAL B CB  1 
ATOM   12084 C  CG1 . VAL B 1 759 ? 208.169 233.641 155.830 1.00 33.04  ? 759 VAL B CG1 1 
ATOM   12085 C  CG2 . VAL B 1 759 ? 206.004 233.571 154.643 1.00 42.48  ? 759 VAL B CG2 1 
ATOM   12086 N  N   . VAL B 1 760 ? 208.404 236.891 157.014 1.00 51.36  ? 760 VAL B N   1 
ATOM   12087 C  CA  . VAL B 1 760 ? 209.351 237.971 157.243 1.00 41.86  ? 760 VAL B CA  1 
ATOM   12088 C  C   . VAL B 1 760 ? 210.742 237.379 157.355 1.00 42.17  ? 760 VAL B C   1 
ATOM   12089 O  O   . VAL B 1 760 ? 210.914 236.208 157.680 1.00 48.08  ? 760 VAL B O   1 
ATOM   12090 C  CB  . VAL B 1 760 ? 209.011 238.755 158.515 1.00 39.72  ? 760 VAL B CB  1 
ATOM   12091 C  CG1 . VAL B 1 760 ? 209.642 240.127 158.488 1.00 54.28  ? 760 VAL B CG1 1 
ATOM   12092 C  CG2 . VAL B 1 760 ? 207.520 238.860 158.666 1.00 44.98  ? 760 VAL B CG2 1 
ATOM   12093 N  N   . ALA B 1 761 ? 211.744 238.209 157.109 1.00 46.84  ? 761 ALA B N   1 
ATOM   12094 C  CA  . ALA B 1 761 ? 213.131 237.777 157.178 1.00 60.45  ? 761 ALA B CA  1 
ATOM   12095 C  C   . ALA B 1 761 ? 213.922 238.697 158.098 1.00 68.77  ? 761 ALA B C   1 
ATOM   12096 O  O   . ALA B 1 761 ? 213.620 239.887 158.221 1.00 71.25  ? 761 ALA B O   1 
ATOM   12097 C  CB  . ALA B 1 761 ? 213.779 237.741 155.788 1.00 62.29  ? 761 ALA B CB  1 
ATOM   12098 N  N   . GLU B 1 762 ? 214.942 238.133 158.741 1.00 69.13  ? 762 GLU B N   1 
ATOM   12099 C  CA  . GLU B 1 762 ? 215.811 238.863 159.649 1.00 67.16  ? 762 GLU B CA  1 
ATOM   12100 C  C   . GLU B 1 762 ? 217.266 238.660 159.251 1.00 74.00  ? 762 GLU B C   1 
ATOM   12101 O  O   . GLU B 1 762 ? 217.627 237.659 158.628 1.00 76.56  ? 762 GLU B O   1 
ATOM   12102 C  CB  . GLU B 1 762 ? 215.614 238.406 161.091 1.00 65.63  ? 762 GLU B CB  1 
ATOM   12103 C  CG  . GLU B 1 762 ? 214.200 238.550 161.586 1.00 63.98  ? 762 GLU B CG  1 
ATOM   12104 C  CD  . GLU B 1 762 ? 213.674 239.956 161.426 1.00 70.64  ? 762 GLU B CD  1 
ATOM   12105 O  OE1 . GLU B 1 762 ? 214.357 240.898 161.876 1.00 73.40  ? 762 GLU B OE1 1 
ATOM   12106 O  OE2 . GLU B 1 762 ? 212.576 240.120 160.856 1.00 71.62  ? 762 GLU B OE2 1 
ATOM   12107 N  N   . GLY B 1 763 ? 218.108 239.617 159.637 1.00 76.79  ? 763 GLY B N   1 
ATOM   12108 C  CA  . GLY B 1 763 ? 219.532 239.533 159.368 1.00 78.07  ? 763 GLY B CA  1 
ATOM   12109 C  C   . GLY B 1 763 ? 219.928 239.610 157.907 1.00 75.11  ? 763 GLY B C   1 
ATOM   12110 O  O   . GLY B 1 763 ? 220.726 238.801 157.430 1.00 76.41  ? 763 GLY B O   1 
ATOM   12111 N  N   . VAL B 1 764 ? 219.379 240.580 157.188 1.00 68.49  ? 764 VAL B N   1 
ATOM   12112 C  CA  . VAL B 1 764 ? 219.701 240.807 155.787 1.00 68.52  ? 764 VAL B CA  1 
ATOM   12113 C  C   . VAL B 1 764 ? 220.671 241.978 155.693 1.00 78.24  ? 764 VAL B C   1 
ATOM   12114 O  O   . VAL B 1 764 ? 220.393 243.065 156.215 1.00 82.33  ? 764 VAL B O   1 
ATOM   12115 C  CB  . VAL B 1 764 ? 218.428 241.070 154.971 1.00 64.40  ? 764 VAL B CB  1 
ATOM   12116 C  CG1 . VAL B 1 764 ? 218.782 241.558 153.584 1.00 67.21  ? 764 VAL B CG1 1 
ATOM   12117 C  CG2 . VAL B 1 764 ? 217.601 239.813 154.896 1.00 67.66  ? 764 VAL B CG2 1 
ATOM   12118 N  N   . GLU B 1 765 ? 221.813 241.763 155.030 1.00 79.74  ? 765 GLU B N   1 
ATOM   12119 C  CA  . GLU B 1 765 ? 222.871 242.769 154.982 1.00 75.90  ? 765 GLU B CA  1 
ATOM   12120 C  C   . GLU B 1 765 ? 223.477 243.020 153.606 1.00 72.95  ? 765 GLU B C   1 
ATOM   12121 O  O   . GLU B 1 765 ? 224.024 244.109 153.397 1.00 73.99  ? 765 GLU B O   1 
ATOM   12122 C  CB  . GLU B 1 765 ? 224.004 242.397 155.947 1.00 78.09  ? 765 GLU B CB  1 
ATOM   12123 C  CG  . GLU B 1 765 ? 223.621 242.510 157.409 1.00 79.84  ? 765 GLU B CG  1 
ATOM   12124 C  CD  . GLU B 1 765 ? 224.725 242.058 158.341 1.00 87.49  ? 765 GLU B CD  1 
ATOM   12125 O  OE1 . GLU B 1 765 ? 225.881 241.939 157.883 1.00 89.68  ? 765 GLU B OE1 1 
ATOM   12126 O  OE2 . GLU B 1 765 ? 224.436 241.822 159.533 1.00 89.55  ? 765 GLU B OE2 1 
ATOM   12127 N  N   . THR B 1 766 ? 223.406 242.083 152.669 1.00 71.25  ? 766 THR B N   1 
ATOM   12128 C  CA  . THR B 1 766 ? 223.998 242.260 151.350 1.00 69.96  ? 766 THR B CA  1 
ATOM   12129 C  C   . THR B 1 766 ? 222.905 242.297 150.291 1.00 71.03  ? 766 THR B C   1 
ATOM   12130 O  O   . THR B 1 766 ? 221.715 242.227 150.591 1.00 72.78  ? 766 THR B O   1 
ATOM   12131 C  CB  . THR B 1 766 ? 225.004 241.150 151.043 1.00 72.54  ? 766 THR B CB  1 
ATOM   12132 O  OG1 . THR B 1 766 ? 224.313 240.020 150.503 1.00 76.48  ? 766 THR B OG1 1 
ATOM   12133 C  CG2 . THR B 1 766 ? 225.730 240.734 152.302 1.00 69.72  ? 766 THR B CG2 1 
ATOM   12134 N  N   . LYS B 1 767 ? 223.323 242.401 149.032 1.00 72.45  ? 767 LYS B N   1 
ATOM   12135 C  CA  . LYS B 1 767 ? 222.377 242.522 147.929 1.00 77.91  ? 767 LYS B CA  1 
ATOM   12136 C  C   . LYS B 1 767 ? 221.949 241.174 147.360 1.00 80.42  ? 767 LYS B C   1 
ATOM   12137 O  O   . LYS B 1 767 ? 220.777 240.999 147.001 1.00 82.45  ? 767 LYS B O   1 
ATOM   12138 C  CB  . LYS B 1 767 ? 222.975 243.394 146.820 1.00 85.51  ? 767 LYS B CB  1 
ATOM   12139 C  CG  . LYS B 1 767 ? 224.336 242.939 146.312 1.00 90.23  ? 767 LYS B CG  1 
ATOM   12140 C  CD  . LYS B 1 767 ? 224.818 243.824 145.171 1.00 90.25  ? 767 LYS B CD  1 
ATOM   12141 C  CE  . LYS B 1 767 ? 226.271 243.543 144.817 1.00 94.50  ? 767 LYS B CE  1 
ATOM   12142 N  NZ  . LYS B 1 767 ? 226.469 242.162 144.297 1.00 98.07  ? 767 LYS B NZ  1 
ATOM   12143 N  N   . GLU B 1 768 ? 222.872 240.215 147.267 1.00 82.09  ? 768 GLU B N   1 
ATOM   12144 C  CA  . GLU B 1 768 ? 222.513 238.899 146.748 1.00 86.09  ? 768 GLU B CA  1 
ATOM   12145 C  C   . GLU B 1 768 ? 221.497 238.208 147.647 1.00 84.15  ? 768 GLU B C   1 
ATOM   12146 O  O   . GLU B 1 768 ? 220.649 237.446 147.162 1.00 79.94  ? 768 GLU B O   1 
ATOM   12147 C  CB  . GLU B 1 768 ? 223.765 238.036 146.599 1.00 87.65  ? 768 GLU B CB  1 
ATOM   12148 C  CG  . GLU B 1 768 ? 224.827 238.630 145.691 1.00 87.93  ? 768 GLU B CG  1 
ATOM   12149 C  CD  . GLU B 1 768 ? 225.838 239.470 146.449 1.00 92.62  ? 768 GLU B CD  1 
ATOM   12150 O  OE1 . GLU B 1 768 ? 225.905 239.346 147.690 1.00 90.29  ? 768 GLU B OE1 1 
ATOM   12151 O  OE2 . GLU B 1 768 ? 226.569 240.251 145.804 1.00 97.80  ? 768 GLU B OE2 1 
ATOM   12152 N  N   . GLN B 1 769 ? 221.574 238.457 148.957 1.00 82.82  ? 769 GLN B N   1 
ATOM   12153 C  CA  . GLN B 1 769 ? 220.574 237.934 149.877 1.00 78.41  ? 769 GLN B CA  1 
ATOM   12154 C  C   . GLN B 1 769 ? 219.182 238.380 149.468 1.00 73.47  ? 769 GLN B C   1 
ATOM   12155 O  O   . GLN B 1 769 ? 218.270 237.557 149.320 1.00 76.11  ? 769 GLN B O   1 
ATOM   12156 C  CB  . GLN B 1 769 ? 220.869 238.405 151.297 1.00 74.29  ? 769 GLN B CB  1 
ATOM   12157 C  CG  . GLN B 1 769 ? 222.151 237.893 151.891 1.00 75.91  ? 769 GLN B CG  1 
ATOM   12158 C  CD  . GLN B 1 769 ? 222.242 238.218 153.358 1.00 76.12  ? 769 GLN B CD  1 
ATOM   12159 O  OE1 . GLN B 1 769 ? 221.234 238.508 153.996 1.00 74.36  ? 769 GLN B OE1 1 
ATOM   12160 N  NE2 . GLN B 1 769 ? 223.448 238.183 153.903 1.00 80.57  ? 769 GLN B NE2 1 
ATOM   12161 N  N   . PHE B 1 770 ? 219.002 239.686 149.279 1.00 69.26  ? 770 PHE B N   1 
ATOM   12162 C  CA  . PHE B 1 770 ? 217.700 240.194 148.883 1.00 68.30  ? 770 PHE B CA  1 
ATOM   12163 C  C   . PHE B 1 770 ? 217.299 239.634 147.533 1.00 70.36  ? 770 PHE B C   1 
ATOM   12164 O  O   . PHE B 1 770 ? 216.130 239.295 147.316 1.00 75.71  ? 770 PHE B O   1 
ATOM   12165 C  CB  . PHE B 1 770 ? 217.718 241.716 148.841 1.00 67.60  ? 770 PHE B CB  1 
ATOM   12166 C  CG  . PHE B 1 770 ? 216.381 242.329 148.572 1.00 61.44  ? 770 PHE B CG  1 
ATOM   12167 C  CD1 . PHE B 1 770 ? 215.523 242.613 149.607 1.00 63.15  ? 770 PHE B CD1 1 
ATOM   12168 C  CD2 . PHE B 1 770 ? 215.985 242.616 147.287 1.00 61.53  ? 770 PHE B CD2 1 
ATOM   12169 C  CE1 . PHE B 1 770 ? 214.296 243.180 149.368 1.00 65.74  ? 770 PHE B CE1 1 
ATOM   12170 C  CE2 . PHE B 1 770 ? 214.761 243.181 147.039 1.00 67.45  ? 770 PHE B CE2 1 
ATOM   12171 C  CZ  . PHE B 1 770 ? 213.914 243.464 148.080 1.00 67.82  ? 770 PHE B CZ  1 
ATOM   12172 N  N   . GLU B 1 771 ? 218.261 239.514 146.618 1.00 72.81  ? 771 GLU B N   1 
ATOM   12173 C  CA  . GLU B 1 771 ? 217.945 239.014 145.285 1.00 80.62  ? 771 GLU B CA  1 
ATOM   12174 C  C   . GLU B 1 771 ? 217.354 237.610 145.349 1.00 79.93  ? 771 GLU B C   1 
ATOM   12175 O  O   . GLU B 1 771 ? 216.269 237.352 144.808 1.00 78.21  ? 771 GLU B O   1 
ATOM   12176 C  CB  . GLU B 1 771 ? 219.196 239.038 144.409 1.00 85.71  ? 771 GLU B CB  1 
ATOM   12177 C  CG  . GLU B 1 771 ? 219.564 240.427 143.914 1.00 92.49  ? 771 GLU B CG  1 
ATOM   12178 C  CD  . GLU B 1 771 ? 218.987 240.730 142.547 1.00 100.24 ? 771 GLU B CD  1 
ATOM   12179 O  OE1 . GLU B 1 771 ? 217.816 240.371 142.303 1.00 98.91  ? 771 GLU B OE1 1 
ATOM   12180 O  OE2 . GLU B 1 771 ? 219.703 241.327 141.717 1.00 105.44 ? 771 GLU B OE2 1 
ATOM   12181 N  N   . MET B 1 772 ? 218.038 236.691 146.035 1.00 79.25  ? 772 MET B N   1 
ATOM   12182 C  CA  . MET B 1 772 ? 217.542 235.318 146.061 1.00 74.43  ? 772 MET B CA  1 
ATOM   12183 C  C   . MET B 1 772 ? 216.274 235.209 146.896 1.00 68.84  ? 772 MET B C   1 
ATOM   12184 O  O   . MET B 1 772 ? 215.361 234.458 146.541 1.00 69.25  ? 772 MET B O   1 
ATOM   12185 C  CB  . MET B 1 772 ? 218.615 234.351 146.569 1.00 78.46  ? 772 MET B CB  1 
ATOM   12186 C  CG  . MET B 1 772 ? 219.128 234.556 147.984 1.00 81.48  ? 772 MET B CG  1 
ATOM   12187 S  SD  . MET B 1 772 ? 217.963 233.992 149.242 1.00 86.30  ? 772 MET B SD  1 
ATOM   12188 C  CE  . MET B 1 772 ? 218.428 232.269 149.386 1.00 89.22  ? 772 MET B CE  1 
ATOM   12189 N  N   . LEU B 1 773 ? 216.190 235.949 148.005 1.00 69.77  ? 773 LEU B N   1 
ATOM   12190 C  CA  . LEU B 1 773 ? 214.997 235.874 148.837 1.00 67.85  ? 773 LEU B CA  1 
ATOM   12191 C  C   . LEU B 1 773 ? 213.768 236.349 148.079 1.00 64.34  ? 773 LEU B C   1 
ATOM   12192 O  O   . LEU B 1 773 ? 212.687 235.766 148.207 1.00 66.37  ? 773 LEU B O   1 
ATOM   12193 C  CB  . LEU B 1 773 ? 215.190 236.684 150.115 1.00 65.20  ? 773 LEU B CB  1 
ATOM   12194 C  CG  . LEU B 1 773 ? 215.808 235.911 151.279 1.00 67.52  ? 773 LEU B CG  1 
ATOM   12195 C  CD1 . LEU B 1 773 ? 215.815 236.748 152.545 1.00 68.68  ? 773 LEU B CD1 1 
ATOM   12196 C  CD2 . LEU B 1 773 ? 215.069 234.607 151.505 1.00 70.48  ? 773 LEU B CD2 1 
ATOM   12197 N  N   . ARG B 1 774 ? 213.903 237.407 147.286 1.00 60.23  ? 774 ARG B N   1 
ATOM   12198 C  CA  . ARG B 1 774 ? 212.789 237.784 146.433 1.00 60.19  ? 774 ARG B CA  1 
ATOM   12199 C  C   . ARG B 1 774 ? 212.559 236.755 145.337 1.00 68.87  ? 774 ARG B C   1 
ATOM   12200 O  O   . ARG B 1 774 ? 211.426 236.598 144.868 1.00 72.53  ? 774 ARG B O   1 
ATOM   12201 C  CB  . ARG B 1 774 ? 213.027 239.163 145.832 1.00 63.77  ? 774 ARG B CB  1 
ATOM   12202 C  CG  . ARG B 1 774 ? 211.771 239.834 145.322 1.00 62.79  ? 774 ARG B CG  1 
ATOM   12203 C  CD  . ARG B 1 774 ? 211.945 241.327 145.347 1.00 65.25  ? 774 ARG B CD  1 
ATOM   12204 N  NE  . ARG B 1 774 ? 211.144 241.994 144.331 1.00 68.28  ? 774 ARG B NE  1 
ATOM   12205 C  CZ  . ARG B 1 774 ? 211.632 242.478 143.199 1.00 71.64  ? 774 ARG B CZ  1 
ATOM   12206 N  NH1 . ARG B 1 774 ? 212.919 242.386 142.906 1.00 69.01  ? 774 ARG B NH1 1 
ATOM   12207 N  NH2 . ARG B 1 774 ? 210.811 243.071 142.338 1.00 74.68  ? 774 ARG B NH2 1 
ATOM   12208 N  N   . LYS B 1 775 ? 213.611 236.047 144.914 1.00 71.20  ? 775 LYS B N   1 
ATOM   12209 C  CA  . LYS B 1 775 ? 213.433 235.009 143.901 1.00 72.91  ? 775 LYS B CA  1 
ATOM   12210 C  C   . LYS B 1 775 ? 212.557 233.869 144.406 1.00 70.70  ? 775 LYS B C   1 
ATOM   12211 O  O   . LYS B 1 775 ? 211.838 233.244 143.618 1.00 70.94  ? 775 LYS B O   1 
ATOM   12212 C  CB  . LYS B 1 775 ? 214.791 234.472 143.451 1.00 76.25  ? 775 LYS B CB  1 
ATOM   12213 C  CG  . LYS B 1 775 ? 214.718 233.501 142.289 1.00 82.68  ? 775 LYS B CG  1 
ATOM   12214 C  CD  . LYS B 1 775 ? 216.101 233.198 141.735 1.00 90.35  ? 775 LYS B CD  1 
ATOM   12215 C  CE  . LYS B 1 775 ? 216.930 232.403 142.732 1.00 89.05  ? 775 LYS B CE  1 
ATOM   12216 N  NZ  . LYS B 1 775 ? 218.296 232.111 142.217 1.00 91.21  ? 775 LYS B NZ  1 
ATOM   12217 N  N   . ILE B 1 776 ? 212.596 233.587 145.705 1.00 66.95  ? 776 ILE B N   1 
ATOM   12218 C  CA  . ILE B 1 776 ? 211.803 232.520 146.294 1.00 58.28  ? 776 ILE B CA  1 
ATOM   12219 C  C   . ILE B 1 776 ? 210.434 233.029 146.731 1.00 54.58  ? 776 ILE B C   1 
ATOM   12220 O  O   . ILE B 1 776 ? 209.720 232.340 147.452 1.00 54.89  ? 776 ILE B O   1 
ATOM   12221 C  CB  . ILE B 1 776 ? 212.538 231.850 147.460 1.00 58.59  ? 776 ILE B CB  1 
ATOM   12222 C  CG1 . ILE B 1 776 ? 212.457 232.716 148.709 1.00 58.58  ? 776 ILE B CG1 1 
ATOM   12223 C  CG2 . ILE B 1 776 ? 213.989 231.659 147.108 1.00 64.69  ? 776 ILE B CG2 1 
ATOM   12224 C  CD1 . ILE B 1 776 ? 212.904 232.004 149.960 1.00 65.96  ? 776 ILE B CD1 1 
ATOM   12225 N  N   . HIS B 1 777 ? 210.059 234.224 146.295 1.00 56.65  ? 777 HIS B N   1 
ATOM   12226 C  CA  . HIS B 1 777 ? 208.797 234.850 146.661 1.00 59.34  ? 777 HIS B CA  1 
ATOM   12227 C  C   . HIS B 1 777 ? 208.690 234.964 148.181 1.00 63.10  ? 777 HIS B C   1 
ATOM   12228 O  O   . HIS B 1 777 ? 207.732 234.484 148.787 1.00 65.36  ? 777 HIS B O   1 
ATOM   12229 C  CB  . HIS B 1 777 ? 207.621 234.072 146.046 1.00 61.51  ? 777 HIS B CB  1 
ATOM   12230 C  CG  . HIS B 1 777 ? 206.267 234.673 146.274 1.00 68.56  ? 777 HIS B CG  1 
ATOM   12231 N  ND1 . HIS B 1 777 ? 205.966 235.360 147.430 1.00 68.66  ? 777 HIS B ND1 1 
ATOM   12232 C  CD2 . HIS B 1 777 ? 205.125 234.653 145.547 1.00 74.19  ? 777 HIS B CD2 1 
ATOM   12233 C  CE1 . HIS B 1 777 ? 204.711 235.767 147.389 1.00 75.52  ? 777 HIS B CE1 1 
ATOM   12234 N  NE2 . HIS B 1 777 ? 204.177 235.351 146.255 1.00 78.56  ? 777 HIS B NE2 1 
ATOM   12235 N  N   . CYS B 1 778 ? 209.742 235.477 148.819 1.00 61.50  ? 778 CYS B N   1 
ATOM   12236 C  CA  . CYS B 1 778 ? 209.668 235.864 150.222 1.00 52.18  ? 778 CYS B CA  1 
ATOM   12237 C  C   . CYS B 1 778 ? 209.059 237.250 150.319 1.00 47.67  ? 778 CYS B C   1 
ATOM   12238 O  O   . CYS B 1 778 ? 209.438 238.155 149.578 1.00 51.39  ? 778 CYS B O   1 
ATOM   12239 C  CB  . CYS B 1 778 ? 211.054 235.842 150.854 1.00 53.31  ? 778 CYS B CB  1 
ATOM   12240 S  SG  . CYS B 1 778 ? 211.066 235.637 152.629 1.00 62.74  ? 778 CYS B SG  1 
ATOM   12241 N  N   . ARG B 1 779 ? 208.108 237.421 151.228 1.00 49.20  ? 779 ARG B N   1 
ATOM   12242 C  CA  . ARG B 1 779 ? 207.247 238.594 151.150 1.00 54.96  ? 779 ARG B CA  1 
ATOM   12243 C  C   . ARG B 1 779 ? 207.957 239.864 151.608 1.00 58.53  ? 779 ARG B C   1 
ATOM   12244 O  O   . ARG B 1 779 ? 208.118 240.807 150.828 1.00 65.92  ? 779 ARG B O   1 
ATOM   12245 C  CB  . ARG B 1 779 ? 205.975 238.371 151.967 1.00 62.58  ? 779 ARG B CB  1 
ATOM   12246 C  CG  . ARG B 1 779 ? 204.935 237.535 151.246 1.00 67.32  ? 779 ARG B CG  1 
ATOM   12247 C  CD  . ARG B 1 779 ? 203.590 237.600 151.941 1.00 67.69  ? 779 ARG B CD  1 
ATOM   12248 N  NE  . ARG B 1 779 ? 203.073 238.962 151.995 1.00 74.35  ? 779 ARG B NE  1 
ATOM   12249 C  CZ  . ARG B 1 779 ? 202.497 239.583 150.975 1.00 70.98  ? 779 ARG B CZ  1 
ATOM   12250 N  NH1 . ARG B 1 779 ? 202.360 238.997 149.797 1.00 73.49  ? 779 ARG B NH1 1 
ATOM   12251 N  NH2 . ARG B 1 779 ? 202.045 240.821 151.141 1.00 66.33  ? 779 ARG B NH2 1 
ATOM   12252 N  N   . VAL B 1 780 ? 208.387 239.913 152.869 1.00 57.01  ? 780 VAL B N   1 
ATOM   12253 C  CA  . VAL B 1 780 ? 208.907 241.140 153.456 1.00 58.40  ? 780 VAL B CA  1 
ATOM   12254 C  C   . VAL B 1 780 ? 210.262 240.882 154.094 1.00 60.89  ? 780 VAL B C   1 
ATOM   12255 O  O   . VAL B 1 780 ? 210.569 239.776 154.539 1.00 64.70  ? 780 VAL B O   1 
ATOM   12256 C  CB  . VAL B 1 780 ? 207.938 241.726 154.488 1.00 54.30  ? 780 VAL B CB  1 
ATOM   12257 C  CG1 . VAL B 1 780 ? 206.632 242.069 153.813 1.00 58.47  ? 780 VAL B CG1 1 
ATOM   12258 C  CG2 . VAL B 1 780 ? 207.716 240.736 155.571 1.00 51.23  ? 780 VAL B CG2 1 
ATOM   12259 N  N   . ILE B 1 781 ? 211.078 241.932 154.143 1.00 56.82  ? 781 ILE B N   1 
ATOM   12260 C  CA  . ILE B 1 781 ? 212.480 241.813 154.512 1.00 57.10  ? 781 ILE B CA  1 
ATOM   12261 C  C   . ILE B 1 781 ? 212.809 242.841 155.582 1.00 62.71  ? 781 ILE B C   1 
ATOM   12262 O  O   . ILE B 1 781 ? 212.253 243.948 155.594 1.00 64.84  ? 781 ILE B O   1 
ATOM   12263 C  CB  . ILE B 1 781 ? 213.403 241.979 153.289 1.00 55.90  ? 781 ILE B CB  1 
ATOM   12264 C  CG1 . ILE B 1 781 ? 213.005 241.007 152.187 1.00 56.94  ? 781 ILE B CG1 1 
ATOM   12265 C  CG2 . ILE B 1 781 ? 214.828 241.689 153.656 1.00 59.20  ? 781 ILE B CG2 1 
ATOM   12266 C  CD1 . ILE B 1 781 ? 213.228 239.559 152.547 1.00 62.77  ? 781 ILE B CD1 1 
ATOM   12267 N  N   . GLN B 1 782 ? 213.691 242.450 156.504 1.00 65.04  ? 782 GLN B N   1 
ATOM   12268 C  CA  . GLN B 1 782 ? 214.213 243.319 157.545 1.00 61.18  ? 782 GLN B CA  1 
ATOM   12269 C  C   . GLN B 1 782 ? 215.702 243.060 157.712 1.00 67.62  ? 782 GLN B C   1 
ATOM   12270 O  O   . GLN B 1 782 ? 216.196 241.977 157.392 1.00 66.66  ? 782 GLN B O   1 
ATOM   12271 C  CB  . GLN B 1 782 ? 213.504 243.095 158.876 1.00 58.03  ? 782 GLN B CB  1 
ATOM   12272 C  CG  . GLN B 1 782 ? 213.871 244.118 159.919 1.00 69.19  ? 782 GLN B CG  1 
ATOM   12273 C  CD  . GLN B 1 782 ? 213.126 243.924 161.202 1.00 71.89  ? 782 GLN B CD  1 
ATOM   12274 O  OE1 . GLN B 1 782 ? 211.917 243.731 161.202 1.00 70.16  ? 782 GLN B OE1 1 
ATOM   12275 N  NE2 . GLN B 1 782 ? 213.845 243.969 162.316 1.00 72.04  ? 782 GLN B NE2 1 
ATOM   12276 N  N   . GLY B 1 783 ? 216.412 244.063 158.205 1.00 70.13  ? 783 GLY B N   1 
ATOM   12277 C  CA  . GLY B 1 783 ? 217.828 243.938 158.472 1.00 72.48  ? 783 GLY B CA  1 
ATOM   12278 C  C   . GLY B 1 783 ? 218.513 245.280 158.339 1.00 73.01  ? 783 GLY B C   1 
ATOM   12279 O  O   . GLY B 1 783 ? 217.876 246.326 158.359 1.00 70.99  ? 783 GLY B O   1 
ATOM   12280 N  N   . TYR B 1 784 ? 219.843 245.222 158.212 1.00 76.97  ? 784 TYR B N   1 
ATOM   12281 C  CA  . TYR B 1 784 ? 220.648 246.422 158.006 1.00 76.87  ? 784 TYR B CA  1 
ATOM   12282 C  C   . TYR B 1 784 ? 220.625 246.912 156.568 1.00 70.69  ? 784 TYR B C   1 
ATOM   12283 O  O   . TYR B 1 784 ? 220.994 248.062 156.317 1.00 71.86  ? 784 TYR B O   1 
ATOM   12284 C  CB  . TYR B 1 784 ? 222.102 246.171 158.405 1.00 78.24  ? 784 TYR B CB  1 
ATOM   12285 C  CG  . TYR B 1 784 ? 222.369 246.241 159.886 1.00 84.58  ? 784 TYR B CG  1 
ATOM   12286 C  CD1 . TYR B 1 784 ? 221.338 246.126 160.806 1.00 85.59  ? 784 TYR B CD1 1 
ATOM   12287 C  CD2 . TYR B 1 784 ? 223.658 246.412 160.366 1.00 93.24  ? 784 TYR B CD2 1 
ATOM   12288 C  CE1 . TYR B 1 784 ? 221.583 246.183 162.162 1.00 95.72  ? 784 TYR B CE1 1 
ATOM   12289 C  CE2 . TYR B 1 784 ? 223.914 246.472 161.719 1.00 101.72 ? 784 TYR B CE2 1 
ATOM   12290 C  CZ  . TYR B 1 784 ? 222.873 246.358 162.614 1.00 103.77 ? 784 TYR B CZ  1 
ATOM   12291 O  OH  . TYR B 1 784 ? 223.122 246.418 163.965 1.00 103.58 ? 784 TYR B OH  1 
ATOM   12292 N  N   . PHE B 1 785 ? 220.206 246.068 155.627 1.00 63.71  ? 785 PHE B N   1 
ATOM   12293 C  CA  . PHE B 1 785 ? 220.215 246.455 154.223 1.00 61.85  ? 785 PHE B CA  1 
ATOM   12294 C  C   . PHE B 1 785 ? 219.359 247.687 153.994 1.00 63.83  ? 785 PHE B C   1 
ATOM   12295 O  O   . PHE B 1 785 ? 219.757 248.614 153.280 1.00 71.87  ? 785 PHE B O   1 
ATOM   12296 C  CB  . PHE B 1 785 ? 219.714 245.296 153.371 1.00 65.87  ? 785 PHE B CB  1 
ATOM   12297 C  CG  . PHE B 1 785 ? 219.817 245.527 151.896 1.00 64.15  ? 785 PHE B CG  1 
ATOM   12298 C  CD1 . PHE B 1 785 ? 218.816 246.187 151.214 1.00 67.15  ? 785 PHE B CD1 1 
ATOM   12299 C  CD2 . PHE B 1 785 ? 220.893 245.042 151.186 1.00 62.20  ? 785 PHE B CD2 1 
ATOM   12300 C  CE1 . PHE B 1 785 ? 218.903 246.383 149.859 1.00 69.45  ? 785 PHE B CE1 1 
ATOM   12301 C  CE2 . PHE B 1 785 ? 220.981 245.227 149.833 1.00 62.37  ? 785 PHE B CE2 1 
ATOM   12302 C  CZ  . PHE B 1 785 ? 219.986 245.901 149.166 1.00 67.57  ? 785 PHE B CZ  1 
ATOM   12303 N  N   . PHE B 1 786 ? 218.175 247.715 154.590 1.00 63.68  ? 786 PHE B N   1 
ATOM   12304 C  CA  . PHE B 1 786 ? 217.248 248.812 154.367 1.00 67.53  ? 786 PHE B CA  1 
ATOM   12305 C  C   . PHE B 1 786 ? 217.435 249.932 155.373 1.00 66.96  ? 786 PHE B C   1 
ATOM   12306 O  O   . PHE B 1 786 ? 217.417 251.107 154.998 1.00 66.74  ? 786 PHE B O   1 
ATOM   12307 C  CB  . PHE B 1 786 ? 215.811 248.299 154.423 1.00 66.49  ? 786 PHE B CB  1 
ATOM   12308 C  CG  . PHE B 1 786 ? 215.380 247.591 153.181 1.00 64.84  ? 786 PHE B CG  1 
ATOM   12309 C  CD1 . PHE B 1 786 ? 215.870 247.974 151.952 1.00 69.23  ? 786 PHE B CD1 1 
ATOM   12310 C  CD2 . PHE B 1 786 ? 214.500 246.534 153.243 1.00 62.20  ? 786 PHE B CD2 1 
ATOM   12311 C  CE1 . PHE B 1 786 ? 215.480 247.321 150.810 1.00 71.96  ? 786 PHE B CE1 1 
ATOM   12312 C  CE2 . PHE B 1 786 ? 214.112 245.881 152.105 1.00 60.58  ? 786 PHE B CE2 1 
ATOM   12313 C  CZ  . PHE B 1 786 ? 214.598 246.275 150.889 1.00 65.46  ? 786 PHE B CZ  1 
ATOM   12314 N  N   . SER B 1 787 ? 217.628 249.592 156.641 1.00 67.91  ? 787 SER B N   1 
ATOM   12315 C  CA  . SER B 1 787 ? 217.689 250.611 157.681 1.00 69.94  ? 787 SER B CA  1 
ATOM   12316 C  C   . SER B 1 787 ? 218.385 250.044 158.903 1.00 74.15  ? 787 SER B C   1 
ATOM   12317 O  O   . SER B 1 787 ? 217.870 249.117 159.534 1.00 76.92  ? 787 SER B O   1 
ATOM   12318 C  CB  . SER B 1 787 ? 216.289 251.089 158.037 1.00 70.70  ? 787 SER B CB  1 
ATOM   12319 O  OG  . SER B 1 787 ? 215.365 250.015 157.988 1.00 70.06  ? 787 SER B OG  1 
ATOM   12320 N  N   . ARG B 1 788 ? 219.544 250.598 159.236 1.00 77.45  ? 788 ARG B N   1 
ATOM   12321 C  CA  . ARG B 1 788 ? 220.126 250.367 160.543 1.00 76.87  ? 788 ARG B CA  1 
ATOM   12322 C  C   . ARG B 1 788 ? 219.128 250.848 161.593 1.00 71.10  ? 788 ARG B C   1 
ATOM   12323 O  O   . ARG B 1 788 ? 218.384 251.796 161.348 1.00 72.36  ? 788 ARG B O   1 
ATOM   12324 C  CB  . ARG B 1 788 ? 221.451 251.124 160.668 1.00 84.41  ? 788 ARG B CB  1 
ATOM   12325 C  CG  . ARG B 1 788 ? 222.389 250.652 161.773 1.00 86.53  ? 788 ARG B CG  1 
ATOM   12326 C  CD  . ARG B 1 788 ? 222.303 251.560 162.992 1.00 90.15  ? 788 ARG B CD  1 
ATOM   12327 N  NE  . ARG B 1 788 ? 223.072 251.046 164.120 1.00 98.78  ? 788 ARG B NE  1 
ATOM   12328 C  CZ  . ARG B 1 788 ? 222.891 251.414 165.380 1.00 94.93  ? 788 ARG B CZ  1 
ATOM   12329 N  NH1 . ARG B 1 788 ? 221.969 252.303 165.715 1.00 87.85  ? 788 ARG B NH1 1 
ATOM   12330 N  NH2 . ARG B 1 788 ? 223.651 250.877 166.330 1.00 97.78  ? 788 ARG B NH2 1 
ATOM   12331 N  N   . PRO B 1 789 ? 219.054 250.194 162.739 1.00 64.81  ? 789 PRO B N   1 
ATOM   12332 C  CA  . PRO B 1 789 ? 218.058 250.595 163.740 1.00 64.81  ? 789 PRO B CA  1 
ATOM   12333 C  C   . PRO B 1 789 ? 218.110 252.078 164.081 1.00 72.63  ? 789 PRO B C   1 
ATOM   12334 O  O   . PRO B 1 789 ? 219.064 252.546 164.708 1.00 78.40  ? 789 PRO B O   1 
ATOM   12335 C  CB  . PRO B 1 789 ? 218.424 249.730 164.948 1.00 61.48  ? 789 PRO B CB  1 
ATOM   12336 C  CG  . PRO B 1 789 ? 219.055 248.532 164.363 1.00 64.64  ? 789 PRO B CG  1 
ATOM   12337 C  CD  . PRO B 1 789 ? 219.760 248.962 163.121 1.00 64.96  ? 789 PRO B CD  1 
ATOM   12338 N  N   . LEU B 1 790 ? 217.074 252.828 163.667 1.00 69.77  ? 790 LEU B N   1 
ATOM   12339 C  CA  . LEU B 1 790 ? 216.977 254.248 163.981 1.00 66.23  ? 790 LEU B CA  1 
ATOM   12340 C  C   . LEU B 1 790 ? 216.443 254.446 165.394 1.00 63.74  ? 790 LEU B C   1 
ATOM   12341 O  O   . LEU B 1 790 ? 215.575 253.696 165.838 1.00 64.40  ? 790 LEU B O   1 
ATOM   12342 C  CB  . LEU B 1 790 ? 216.065 254.968 162.990 1.00 68.23  ? 790 LEU B CB  1 
ATOM   12343 C  CG  . LEU B 1 790 ? 216.050 254.570 161.515 1.00 74.86  ? 790 LEU B CG  1 
ATOM   12344 C  CD1 . LEU B 1 790 ? 215.213 255.552 160.740 1.00 76.81  ? 790 LEU B CD1 1 
ATOM   12345 C  CD2 . LEU B 1 790 ? 217.458 254.618 160.969 1.00 79.35  ? 790 LEU B CD2 1 
ATOM   12346 N  N   . PRO B 1 791 ? 216.927 255.455 166.107 1.00 62.72  ? 791 PRO B N   1 
ATOM   12347 C  CA  . PRO B 1 791 ? 216.412 255.718 167.453 1.00 58.40  ? 791 PRO B CA  1 
ATOM   12348 C  C   . PRO B 1 791 ? 214.988 256.228 167.416 1.00 57.74  ? 791 PRO B C   1 
ATOM   12349 O  O   . PRO B 1 791 ? 214.384 256.302 166.345 1.00 62.83  ? 791 PRO B O   1 
ATOM   12350 C  CB  . PRO B 1 791 ? 217.381 256.769 168.007 1.00 61.94  ? 791 PRO B CB  1 
ATOM   12351 C  CG  . PRO B 1 791 ? 217.983 257.401 166.807 1.00 67.38  ? 791 PRO B CG  1 
ATOM   12352 C  CD  . PRO B 1 791 ? 218.054 256.334 165.763 1.00 66.70  ? 791 PRO B CD  1 
ATOM   12353 N  N   . ALA B 1 792 ? 214.444 256.583 168.579 1.00 54.54  ? 792 ALA B N   1 
ATOM   12354 C  CA  . ALA B 1 792 ? 213.032 256.928 168.657 1.00 59.69  ? 792 ALA B CA  1 
ATOM   12355 C  C   . ALA B 1 792 ? 212.679 258.072 167.721 1.00 70.95  ? 792 ALA B C   1 
ATOM   12356 O  O   . ALA B 1 792 ? 211.521 258.201 167.308 1.00 74.70  ? 792 ALA B O   1 
ATOM   12357 C  CB  . ALA B 1 792 ? 212.659 257.280 170.093 1.00 60.14  ? 792 ALA B CB  1 
ATOM   12358 N  N   . GLU B 1 793 ? 213.652 258.907 167.374 1.00 72.31  ? 793 GLU B N   1 
ATOM   12359 C  CA  . GLU B 1 793 ? 213.444 259.989 166.433 1.00 68.85  ? 793 GLU B CA  1 
ATOM   12360 C  C   . GLU B 1 793 ? 214.004 259.595 165.073 1.00 66.17  ? 793 GLU B C   1 
ATOM   12361 O  O   . GLU B 1 793 ? 214.470 258.477 164.864 1.00 66.43  ? 793 GLU B O   1 
ATOM   12362 C  CB  . GLU B 1 793 ? 214.079 261.277 166.951 1.00 69.62  ? 793 GLU B CB  1 
ATOM   12363 C  CG  . GLU B 1 793 ? 213.393 261.835 168.184 1.00 72.14  ? 793 GLU B CG  1 
ATOM   12364 C  CD  . GLU B 1 793 ? 211.884 261.873 168.049 1.00 75.95  ? 793 GLU B CD  1 
ATOM   12365 O  OE1 . GLU B 1 793 ? 211.364 262.827 167.436 1.00 80.30  ? 793 GLU B OE1 1 
ATOM   12366 O  OE2 . GLU B 1 793 ? 211.216 260.949 168.557 1.00 73.39  ? 793 GLU B OE2 1 
ATOM   12367 N  N   . GLU B 1 794 ? 213.937 260.532 164.135 1.00 66.43  ? 794 GLU B N   1 
ATOM   12368 C  CA  . GLU B 1 794 ? 214.250 260.340 162.720 1.00 74.97  ? 794 GLU B CA  1 
ATOM   12369 C  C   . GLU B 1 794 ? 213.642 259.071 162.127 1.00 78.46  ? 794 GLU B C   1 
ATOM   12370 O  O   . GLU B 1 794 ? 214.118 258.581 161.099 1.00 79.85  ? 794 GLU B O   1 
ATOM   12371 C  CB  . GLU B 1 794 ? 215.765 260.373 162.430 1.00 76.66  ? 794 GLU B CB  1 
ATOM   12372 C  CG  . GLU B 1 794 ? 216.686 259.340 163.078 1.00 75.06  ? 794 GLU B CG  1 
ATOM   12373 C  CD  . GLU B 1 794 ? 217.352 259.824 164.361 1.00 78.40  ? 794 GLU B CD  1 
ATOM   12374 O  OE1 . GLU B 1 794 ? 216.666 260.178 165.337 1.00 75.94  ? 794 GLU B OE1 1 
ATOM   12375 O  OE2 . GLU B 1 794 ? 218.600 259.846 164.389 1.00 79.37  ? 794 GLU B OE2 1 
ATOM   12376 N  N   . ILE B 1 795 ? 212.583 258.542 162.730 1.00 80.03  ? 795 ILE B N   1 
ATOM   12377 C  CA  . ILE B 1 795 ? 211.766 257.540 162.048 1.00 81.31  ? 795 ILE B CA  1 
ATOM   12378 C  C   . ILE B 1 795 ? 210.780 258.255 161.130 1.00 84.34  ? 795 ILE B C   1 
ATOM   12379 O  O   . ILE B 1 795 ? 210.655 257.859 159.964 1.00 85.96  ? 795 ILE B O   1 
ATOM   12380 C  CB  . ILE B 1 795 ? 211.059 256.592 163.033 1.00 78.61  ? 795 ILE B CB  1 
ATOM   12381 C  CG1 . ILE B 1 795 ? 212.056 255.623 163.661 1.00 75.04  ? 795 ILE B CG1 1 
ATOM   12382 C  CG2 . ILE B 1 795 ? 209.967 255.809 162.330 1.00 76.39  ? 795 ILE B CG2 1 
ATOM   12383 C  CD1 . ILE B 1 795 ? 212.464 254.510 162.726 1.00 72.16  ? 795 ILE B CD1 1 
ATOM   12384 N  N   . PRO B 1 796 ? 210.054 259.287 161.585 1.00 82.06  ? 796 PRO B N   1 
ATOM   12385 C  CA  . PRO B 1 796 ? 209.278 260.077 160.620 1.00 80.05  ? 796 PRO B CA  1 
ATOM   12386 C  C   . PRO B 1 796 ? 210.134 260.706 159.542 1.00 77.85  ? 796 PRO B C   1 
ATOM   12387 O  O   . PRO B 1 796 ? 209.663 260.863 158.412 1.00 81.18  ? 796 PRO B O   1 
ATOM   12388 C  CB  . PRO B 1 796 ? 208.592 261.128 161.499 1.00 71.03  ? 796 PRO B CB  1 
ATOM   12389 C  CG  . PRO B 1 796 ? 208.456 260.465 162.798 1.00 67.53  ? 796 PRO B CG  1 
ATOM   12390 C  CD  . PRO B 1 796 ? 209.718 259.682 162.966 1.00 74.42  ? 796 PRO B CD  1 
ATOM   12391 N  N   . GLY B 1 797 ? 211.384 261.051 159.840 1.00 71.62  ? 797 GLY B N   1 
ATOM   12392 C  CA  . GLY B 1 797 ? 212.258 261.551 158.793 1.00 76.43  ? 797 GLY B CA  1 
ATOM   12393 C  C   . GLY B 1 797 ? 212.529 260.510 157.725 1.00 79.04  ? 797 GLY B C   1 
ATOM   12394 O  O   . GLY B 1 797 ? 212.436 260.788 156.527 1.00 83.17  ? 797 GLY B O   1 
ATOM   12395 N  N   . TRP B 1 798 ? 212.852 259.289 158.150 1.00 74.57  ? 798 TRP B N   1 
ATOM   12396 C  CA  . TRP B 1 798 ? 213.079 258.206 157.201 1.00 77.49  ? 798 TRP B CA  1 
ATOM   12397 C  C   . TRP B 1 798 ? 211.811 257.888 156.418 1.00 83.74  ? 798 TRP B C   1 
ATOM   12398 O  O   . TRP B 1 798 ? 211.861 257.618 155.214 1.00 84.01  ? 798 TRP B O   1 
ATOM   12399 C  CB  . TRP B 1 798 ? 213.568 256.973 157.953 1.00 74.72  ? 798 TRP B CB  1 
ATOM   12400 C  CG  . TRP B 1 798 ? 214.438 256.072 157.159 1.00 73.73  ? 798 TRP B CG  1 
ATOM   12401 C  CD1 . TRP B 1 798 ? 215.747 256.267 156.848 1.00 74.79  ? 798 TRP B CD1 1 
ATOM   12402 C  CD2 . TRP B 1 798 ? 214.072 254.820 156.582 1.00 73.82  ? 798 TRP B CD2 1 
ATOM   12403 N  NE1 . TRP B 1 798 ? 216.219 255.218 156.105 1.00 72.21  ? 798 TRP B NE1 1 
ATOM   12404 C  CE2 . TRP B 1 798 ? 215.207 254.315 155.928 1.00 73.43  ? 798 TRP B CE2 1 
ATOM   12405 C  CE3 . TRP B 1 798 ? 212.890 254.079 156.548 1.00 75.08  ? 798 TRP B CE3 1 
ATOM   12406 C  CZ2 . TRP B 1 798 ? 215.197 253.106 155.249 1.00 75.11  ? 798 TRP B CZ2 1 
ATOM   12407 C  CZ3 . TRP B 1 798 ? 212.882 252.878 155.875 1.00 76.52  ? 798 TRP B CZ3 1 
ATOM   12408 C  CH2 . TRP B 1 798 ? 214.027 252.401 155.236 1.00 76.62  ? 798 TRP B CH2 1 
ATOM   12409 N  N   . MET B 1 799 ? 210.663 257.919 157.093 1.00 87.25  ? 799 MET B N   1 
ATOM   12410 C  CA  . MET B 1 799 ? 209.395 257.572 156.463 1.00 89.24  ? 799 MET B CA  1 
ATOM   12411 C  C   . MET B 1 799 ? 208.940 258.641 155.479 1.00 89.06  ? 799 MET B C   1 
ATOM   12412 O  O   . MET B 1 799 ? 208.287 258.325 154.480 1.00 90.22  ? 799 MET B O   1 
ATOM   12413 C  CB  . MET B 1 799 ? 208.337 257.345 157.544 1.00 89.62  ? 799 MET B CB  1 
ATOM   12414 C  CG  . MET B 1 799 ? 206.948 257.015 157.033 1.00 93.04  ? 799 MET B CG  1 
ATOM   12415 S  SD  . MET B 1 799 ? 205.737 256.982 158.369 1.00 109.69 ? 799 MET B SD  1 
ATOM   12416 C  CE  . MET B 1 799 ? 204.382 256.119 157.578 1.00 93.79  ? 799 MET B CE  1 
ATOM   12417 N  N   . SER B 1 800 ? 209.261 259.906 155.741 1.00 85.29  ? 800 SER B N   1 
ATOM   12418 C  CA  . SER B 1 800 ? 208.923 260.971 154.813 1.00 83.50  ? 800 SER B CA  1 
ATOM   12419 C  C   . SER B 1 800 ? 209.939 261.116 153.695 1.00 81.28  ? 800 SER B C   1 
ATOM   12420 O  O   . SER B 1 800 ? 209.596 261.640 152.631 1.00 84.15  ? 800 SER B O   1 
ATOM   12421 C  CB  . SER B 1 800 ? 208.800 262.299 155.562 1.00 81.75  ? 800 SER B CB  1 
ATOM   12422 O  OG  . SER B 1 800 ? 209.964 262.552 156.326 1.00 82.47  ? 800 SER B OG  1 
ATOM   12423 N  N   . SER B 1 801 ? 211.167 260.649 153.898 1.00 78.83  ? 801 SER B N   1 
ATOM   12424 C  CA  . SER B 1 801 ? 212.213 260.869 152.909 1.00 82.03  ? 801 SER B CA  1 
ATOM   12425 C  C   . SER B 1 801 ? 212.292 259.733 151.895 1.00 86.50  ? 801 SER B C   1 
ATOM   12426 O  O   . SER B 1 801 ? 212.127 259.957 150.692 1.00 90.14  ? 801 SER B O   1 
ATOM   12427 C  CB  . SER B 1 801 ? 213.562 261.049 153.608 1.00 80.03  ? 801 SER B CB  1 
ATOM   12428 O  OG  . SER B 1 801 ? 214.005 259.826 154.165 1.00 82.62  ? 801 SER B OG  1 
ATOM   12429 N  N   . VAL B 1 802 ? 212.538 258.512 152.362 1.00 86.91  ? 802 VAL B N   1 
ATOM   12430 C  CA  . VAL B 1 802 ? 212.912 257.428 151.460 1.00 91.61  ? 802 VAL B CA  1 
ATOM   12431 C  C   . VAL B 1 802 ? 212.018 256.208 151.638 1.00 91.27  ? 802 VAL B C   1 
ATOM   12432 O  O   . VAL B 1 802 ? 212.464 255.074 151.437 1.00 91.10  ? 802 VAL B O   1 
ATOM   12433 C  CB  . VAL B 1 802 ? 214.389 257.044 151.659 1.00 89.83  ? 802 VAL B CB  1 
ATOM   12434 C  CG1 . VAL B 1 802 ? 215.298 258.123 151.092 1.00 88.02  ? 802 VAL B CG1 1 
ATOM   12435 C  CG2 . VAL B 1 802 ? 214.683 256.816 153.131 1.00 82.77  ? 802 VAL B CG2 1 
ATOM   12436 N  N   . LEU B 1 803 ? 210.761 256.422 152.019 1.00 89.24  ? 803 LEU B N   1 
ATOM   12437 C  CA  . LEU B 1 803 ? 209.870 255.284 152.242 1.00 90.65  ? 803 LEU B CA  1 
ATOM   12438 C  C   . LEU B 1 803 ? 209.616 254.460 150.986 1.00 90.70  ? 803 LEU B C   1 
ATOM   12439 O  O   . LEU B 1 803 ? 209.709 253.223 151.063 1.00 89.90  ? 803 LEU B O   1 
ATOM   12440 C  CB  . LEU B 1 803 ? 208.556 255.763 152.866 1.00 92.74  ? 803 LEU B CB  1 
ATOM   12441 C  CG  . LEU B 1 803 ? 207.655 254.665 153.433 1.00 93.43  ? 803 LEU B CG  1 
ATOM   12442 C  CD1 . LEU B 1 803 ? 208.302 254.017 154.648 1.00 87.64  ? 803 LEU B CD1 1 
ATOM   12443 C  CD2 . LEU B 1 803 ? 206.284 255.221 153.785 1.00 89.65  ? 803 LEU B CD2 1 
ATOM   12444 N  N   . PRO B 1 804 ? 209.275 255.040 149.823 1.00 90.13  ? 804 PRO B N   1 
ATOM   12445 C  CA  . PRO B 1 804 ? 209.068 254.202 148.627 1.00 87.94  ? 804 PRO B CA  1 
ATOM   12446 C  C   . PRO B 1 804 ? 210.363 253.943 147.861 1.00 86.85  ? 804 PRO B C   1 
ATOM   12447 O  O   . PRO B 1 804 ? 210.541 254.368 146.718 1.00 87.51  ? 804 PRO B O   1 
ATOM   12448 C  CB  . PRO B 1 804 ? 208.058 255.028 147.815 1.00 89.69  ? 804 PRO B CB  1 
ATOM   12449 C  CG  . PRO B 1 804 ? 207.643 256.179 148.706 1.00 89.21  ? 804 PRO B CG  1 
ATOM   12450 C  CD  . PRO B 1 804 ? 208.814 256.412 149.578 1.00 88.14  ? 804 PRO B CD  1 
ATOM   12451 N  N   . LEU B 1 805 ? 211.286 253.226 148.502 1.00 82.86  ? 805 LEU B N   1 
ATOM   12452 C  CA  . LEU B 1 805 ? 212.584 252.926 147.903 1.00 78.79  ? 805 LEU B CA  1 
ATOM   12453 C  C   . LEU B 1 805 ? 212.435 251.731 146.964 1.00 80.55  ? 805 LEU B C   1 
ATOM   12454 O  O   . LEU B 1 805 ? 212.807 250.596 147.262 1.00 82.35  ? 805 LEU B O   1 
ATOM   12455 C  CB  . LEU B 1 805 ? 213.638 252.677 148.975 1.00 79.94  ? 805 LEU B CB  1 
ATOM   12456 C  CG  . LEU B 1 805 ? 213.543 251.559 150.019 1.00 78.10  ? 805 LEU B CG  1 
ATOM   12457 C  CD1 . LEU B 1 805 ? 214.881 251.407 150.715 1.00 75.39  ? 805 LEU B CD1 1 
ATOM   12458 C  CD2 . LEU B 1 805 ? 212.474 251.821 151.043 1.00 80.35  ? 805 LEU B CD2 1 
ATOM   12459 N  N   . LYS B 1 806 ? 211.901 252.019 145.780 1.00 86.35  ? 806 LYS B N   1 
ATOM   12460 C  CA  . LYS B 1 806 ? 211.592 250.977 144.803 1.00 94.77  ? 806 LYS B CA  1 
ATOM   12461 C  C   . LYS B 1 806 ? 212.902 250.406 144.272 1.00 98.52  ? 806 LYS B C   1 
ATOM   12462 O  O   . LYS B 1 806 ? 213.350 250.698 143.160 1.00 102.98 ? 806 LYS B O   1 
ATOM   12463 C  CB  . LYS B 1 806 ? 210.726 251.532 143.678 1.00 93.02  ? 806 LYS B CB  1 
ATOM   12464 C  CG  . LYS B 1 806 ? 209.312 251.890 144.100 1.00 88.79  ? 806 LYS B CG  1 
ATOM   12465 C  CD  . LYS B 1 806 ? 208.472 252.308 142.904 1.00 86.45  ? 806 LYS B CD  1 
ATOM   12466 C  CE  . LYS B 1 806 ? 207.097 252.793 143.336 1.00 86.54  ? 806 LYS B CE  1 
ATOM   12467 N  NZ  . LYS B 1 806 ? 206.271 251.693 143.906 1.00 88.02  ? 806 LYS B NZ  1 
ATOM   12468 N  N   . ILE B 1 807 ? 213.526 249.568 145.093 1.00 94.77  ? 807 ILE B N   1 
ATOM   12469 C  CA  . ILE B 1 807 ? 214.761 248.907 144.712 1.00 98.34  ? 807 ILE B CA  1 
ATOM   12470 C  C   . ILE B 1 807 ? 214.429 247.666 143.900 1.00 101.61 ? 807 ILE B C   1 
ATOM   12471 O  O   . ILE B 1 807 ? 215.085 247.357 142.905 1.00 107.38 ? 807 ILE B O   1 
ATOM   12472 C  CB  . ILE B 1 807 ? 215.610 248.558 145.944 1.00 101.05 ? 807 ILE B CB  1 
ATOM   12473 C  CG1 . ILE B 1 807 ? 216.779 247.652 145.550 1.00 105.04 ? 807 ILE B CG1 1 
ATOM   12474 C  CG2 . ILE B 1 807 ? 214.752 247.899 147.013 1.00 93.25  ? 807 ILE B CG2 1 
ATOM   12475 C  CD1 . ILE B 1 807 ? 217.855 247.547 146.606 1.00 97.55  ? 807 ILE B CD1 1 
ATOM   12476 O  OXT . ILE B 1 807 ? 213.480 246.948 144.212 1.00 94.41  ? 807 ILE B OXT 1 
HETATM 12477 C  CHA . HEM C 2 .   ? 182.970 204.391 283.038 1.00 120.71 ? 901 HEM A CHA 1 
HETATM 12478 C  CHB . HEM C 2 .   ? 181.657 206.705 279.027 1.00 119.42 ? 901 HEM A CHB 1 
HETATM 12479 C  CHC . HEM C 2 .   ? 179.776 210.194 281.762 1.00 109.17 ? 901 HEM A CHC 1 
HETATM 12480 C  CHD . HEM C 2 .   ? 180.197 207.364 285.623 1.00 123.09 ? 901 HEM A CHD 1 
HETATM 12481 C  C1A . HEM C 2 .   ? 182.714 204.655 281.717 1.00 120.30 ? 901 HEM A C1A 1 
HETATM 12482 C  C2A . HEM C 2 .   ? 182.894 203.746 280.607 1.00 124.75 ? 901 HEM A C2A 1 
HETATM 12483 C  C3A . HEM C 2 .   ? 182.523 204.388 279.495 1.00 124.13 ? 901 HEM A C3A 1 
HETATM 12484 C  C4A . HEM C 2 .   ? 182.107 205.722 279.871 1.00 119.54 ? 901 HEM A C4A 1 
HETATM 12485 C  CMA . HEM C 2 .   ? 182.533 203.832 278.054 1.00 123.85 ? 901 HEM A CMA 1 
HETATM 12486 C  CAA . HEM C 2 .   ? 183.408 202.290 280.723 1.00 127.80 ? 901 HEM A CAA 1 
HETATM 12487 C  CBA . HEM C 2 .   ? 184.786 202.102 280.087 1.00 126.04 ? 901 HEM A CBA 1 
HETATM 12488 C  CGA . HEM C 2 .   ? 185.794 203.081 280.634 1.00 126.46 ? 901 HEM A CGA 1 
HETATM 12489 O  O1A . HEM C 2 .   ? 185.601 203.597 281.764 1.00 126.72 ? 901 HEM A O1A 1 
HETATM 12490 O  O2A . HEM C 2 .   ? 186.811 203.335 279.939 1.00 124.83 ? 901 HEM A O2A 1 
HETATM 12491 C  C1B . HEM C 2 .   ? 181.189 207.925 279.442 1.00 119.47 ? 901 HEM A C1B 1 
HETATM 12492 C  C2B . HEM C 2 .   ? 181.155 209.138 278.650 1.00 123.52 ? 901 HEM A C2B 1 
HETATM 12493 C  C3B . HEM C 2 .   ? 180.627 210.109 279.413 1.00 122.10 ? 901 HEM A C3B 1 
HETATM 12494 C  C4B . HEM C 2 .   ? 180.328 209.525 280.703 1.00 114.59 ? 901 HEM A C4B 1 
HETATM 12495 C  CMB . HEM C 2 .   ? 181.644 209.220 277.185 1.00 122.59 ? 901 HEM A CMB 1 
HETATM 12496 C  CAB . HEM C 2 .   ? 180.355 211.604 279.090 1.00 125.87 ? 901 HEM A CAB 1 
HETATM 12497 C  CBB . HEM C 2 .   ? 180.736 212.232 277.971 1.00 124.65 ? 901 HEM A CBB 1 
HETATM 12498 C  C1C . HEM C 2 .   ? 179.689 209.714 283.036 1.00 109.29 ? 901 HEM A C1C 1 
HETATM 12499 C  C2C . HEM C 2 .   ? 179.075 210.406 284.144 1.00 113.80 ? 901 HEM A C2C 1 
HETATM 12500 C  C3C . HEM C 2 .   ? 179.181 209.620 285.225 1.00 116.02 ? 901 HEM A C3C 1 
HETATM 12501 C  C4C . HEM C 2 .   ? 179.878 208.422 284.814 1.00 116.26 ? 901 HEM A C4C 1 
HETATM 12502 C  CMC . HEM C 2 .   ? 178.427 211.803 284.006 1.00 119.82 ? 901 HEM A CMC 1 
HETATM 12503 C  CAC . HEM C 2 .   ? 178.712 209.862 286.683 1.00 123.73 ? 901 HEM A CAC 1 
HETATM 12504 C  CBC . HEM C 2 .   ? 178.258 211.029 287.151 1.00 124.02 ? 901 HEM A CBC 1 
HETATM 12505 C  C1D . HEM C 2 .   ? 180.927 206.268 285.236 1.00 124.08 ? 901 HEM A C1D 1 
HETATM 12506 C  C2D . HEM C 2 .   ? 181.106 205.055 286.003 1.00 130.29 ? 901 HEM A C2D 1 
HETATM 12507 C  C3D . HEM C 2 .   ? 181.874 204.227 285.290 1.00 127.26 ? 901 HEM A C3D 1 
HETATM 12508 C  C4D . HEM C 2 .   ? 182.206 204.894 284.053 1.00 122.19 ? 901 HEM A C4D 1 
HETATM 12509 C  CMD . HEM C 2 .   ? 180.501 204.784 287.399 1.00 141.02 ? 901 HEM A CMD 1 
HETATM 12510 C  CAD . HEM C 2 .   ? 182.337 202.811 285.697 1.00 132.94 ? 901 HEM A CAD 1 
HETATM 12511 C  CBD . HEM C 2 .   ? 183.417 202.898 286.769 1.00 136.41 ? 901 HEM A CBD 1 
HETATM 12512 C  CGD . HEM C 2 .   ? 183.903 201.515 287.114 1.00 137.50 ? 901 HEM A CGD 1 
HETATM 12513 O  O1D . HEM C 2 .   ? 184.922 201.406 287.842 1.00 135.56 ? 901 HEM A O1D 1 
HETATM 12514 O  O2D . HEM C 2 .   ? 183.278 200.523 286.659 1.00 139.68 ? 901 HEM A O2D 1 
HETATM 12515 N  NA  . HEM C 2 .   ? 182.236 205.851 281.233 1.00 116.34 ? 901 HEM A NA  1 
HETATM 12516 N  NB  . HEM C 2 .   ? 180.682 208.194 280.691 1.00 114.16 ? 901 HEM A NB  1 
HETATM 12517 N  NC  . HEM C 2 .   ? 180.170 208.506 283.473 1.00 110.02 ? 901 HEM A NC  1 
HETATM 12518 N  ND  . HEM C 2 .   ? 181.608 206.135 284.048 1.00 120.40 ? 901 HEM A ND  1 
HETATM 12519 FE FE  . HEM C 2 .   ? 181.124 207.119 282.343 1.00 102.77 ? 901 HEM A FE  1 
HETATM 12520 C  CHA . HEM D 2 .   ? 201.547 231.132 293.472 1.00 111.27 ? 901 HEM B CHA 1 
HETATM 12521 C  CHB . HEM D 2 .   ? 204.445 227.355 294.219 1.00 105.20 ? 901 HEM B CHB 1 
HETATM 12522 C  CHC . HEM D 2 .   ? 201.040 225.492 297.065 1.00 110.37 ? 901 HEM B CHC 1 
HETATM 12523 C  CHD . HEM D 2 .   ? 198.492 229.563 296.866 1.00 109.32 ? 901 HEM B CHD 1 
HETATM 12524 C  C1A . HEM D 2 .   ? 202.598 230.257 293.403 1.00 111.21 ? 901 HEM B C1A 1 
HETATM 12525 C  C2A . HEM D 2 .   ? 203.748 230.416 292.542 1.00 111.53 ? 901 HEM B C2A 1 
HETATM 12526 C  C3A . HEM D 2 .   ? 204.556 229.377 292.749 1.00 106.94 ? 901 HEM B C3A 1 
HETATM 12527 C  C4A . HEM D 2 .   ? 203.934 228.528 293.739 1.00 106.26 ? 901 HEM B C4A 1 
HETATM 12528 C  CMA . HEM D 2 .   ? 205.911 229.106 292.060 1.00 106.53 ? 901 HEM B CMA 1 
HETATM 12529 C  CAA . HEM D 2 .   ? 203.974 231.609 291.584 1.00 115.27 ? 901 HEM B CAA 1 
HETATM 12530 C  CBA . HEM D 2 .   ? 203.922 231.207 290.111 1.00 118.47 ? 901 HEM B CBA 1 
HETATM 12531 C  CGA . HEM D 2 .   ? 202.821 230.212 289.846 1.00 123.07 ? 901 HEM B CGA 1 
HETATM 12532 O  O1A . HEM D 2 .   ? 203.061 229.253 289.069 1.00 123.13 ? 901 HEM B O1A 1 
HETATM 12533 O  O2A . HEM D 2 .   ? 201.707 230.373 290.407 1.00 126.50 ? 901 HEM B O2A 1 
HETATM 12534 C  C1B . HEM D 2 .   ? 203.749 226.512 295.036 1.00 108.05 ? 901 HEM B C1B 1 
HETATM 12535 C  C2B . HEM D 2 .   ? 204.199 225.212 295.457 1.00 114.47 ? 901 HEM B C2B 1 
HETATM 12536 C  C3B . HEM D 2 .   ? 203.242 224.685 296.227 1.00 118.17 ? 901 HEM B C3B 1 
HETATM 12537 C  C4B . HEM D 2 .   ? 202.186 225.661 296.337 1.00 110.49 ? 901 HEM B C4B 1 
HETATM 12538 C  CMB . HEM D 2 .   ? 205.539 224.593 295.009 1.00 119.04 ? 901 HEM B CMB 1 
HETATM 12539 C  CAB . HEM D 2 .   ? 203.202 223.327 296.967 1.00 129.65 ? 901 HEM B CAB 1 
HETATM 12540 C  CBB . HEM D 2 .   ? 204.305 222.726 297.422 1.00 134.46 ? 901 HEM B CBB 1 
HETATM 12541 C  C1C . HEM D 2 .   ? 200.048 226.418 297.232 1.00 109.07 ? 901 HEM B C1C 1 
HETATM 12542 C  C2C . HEM D 2 .   ? 198.823 226.185 297.951 1.00 112.49 ? 901 HEM B C2C 1 
HETATM 12543 C  C3C . HEM D 2 .   ? 198.102 227.314 297.907 1.00 114.63 ? 901 HEM B C3C 1 
HETATM 12544 C  C4C . HEM D 2 .   ? 198.865 228.278 297.146 1.00 110.05 ? 901 HEM B C4C 1 
HETATM 12545 C  CMC . HEM D 2 .   ? 198.497 224.835 298.627 1.00 116.83 ? 901 HEM B CMC 1 
HETATM 12546 C  CAC . HEM D 2 .   ? 196.706 227.621 298.506 1.00 123.20 ? 901 HEM B CAC 1 
HETATM 12547 C  CBC . HEM D 2 .   ? 195.908 226.706 299.068 1.00 128.15 ? 901 HEM B CBC 1 
HETATM 12548 C  C1D . HEM D 2 .   ? 199.090 230.341 295.908 1.00 108.74 ? 901 HEM B C1D 1 
HETATM 12549 C  C2D . HEM D 2 .   ? 198.634 231.636 295.459 1.00 111.90 ? 901 HEM B C2D 1 
HETATM 12550 C  C3D . HEM D 2 .   ? 199.470 232.065 294.518 1.00 112.20 ? 901 HEM B C3D 1 
HETATM 12551 C  C4D . HEM D 2 .   ? 200.495 231.061 294.344 1.00 109.69 ? 901 HEM B C4D 1 
HETATM 12552 C  CMD . HEM D 2 .   ? 197.392 232.389 295.975 1.00 119.82 ? 901 HEM B CMD 1 
HETATM 12553 C  CAD . HEM D 2 .   ? 199.361 233.415 293.778 1.00 116.17 ? 901 HEM B CAD 1 
HETATM 12554 C  CBD . HEM D 2 .   ? 199.198 233.215 292.276 1.00 121.82 ? 901 HEM B CBD 1 
HETATM 12555 C  CGD . HEM D 2 .   ? 199.062 234.559 291.608 1.00 131.36 ? 901 HEM B CGD 1 
HETATM 12556 O  O1D . HEM D 2 .   ? 199.160 235.595 292.316 1.00 133.34 ? 901 HEM B O1D 1 
HETATM 12557 O  O2D . HEM D 2 .   ? 198.857 234.597 290.368 1.00 135.35 ? 901 HEM B O2D 1 
HETATM 12558 N  NA  . HEM D 2 .   ? 202.734 229.089 294.122 1.00 106.75 ? 901 HEM B NA  1 
HETATM 12559 N  NB  . HEM D 2 .   ? 202.519 226.766 295.595 1.00 106.46 ? 901 HEM B NB  1 
HETATM 12560 N  NC  . HEM D 2 .   ? 200.048 227.703 296.756 1.00 107.18 ? 901 HEM B NC  1 
HETATM 12561 N  ND  . HEM D 2 .   ? 200.232 230.019 295.207 1.00 108.01 ? 901 HEM B ND  1 
HETATM 12562 FE FE  . HEM D 2 .   ? 201.447 228.429 295.510 1.00 95.06  ? 901 HEM B FE  1 
# 
