data_9BH0
# 
_entry.id   9BH0 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BH0         pdb_00009bh0 10.2210/pdb9bh0/pdb 
WWPDB D_1000283051 ?            ?                   
EMDB  EMD-44528    ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-03-12 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BH0 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Ancestral uncoupled aspartate transporter in complex with L-aspartate' 
_pdbx_database_related.db_id          EMD-44528 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              olb2003@med.cornell.edu 
_pdbx_contact_author.name_first         Olga 
_pdbx_contact_author.name_last          Boudker 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6965-0851 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Reddy, K.D.' 1 0000-0002-0475-8375 
'Boudker, O.' 2 0000-0001-6965-0851 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2023.12.03.569786 
_citation.pdbx_database_id_PubMed   38106174 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Reddy, K.D.'  1 0000-0002-0475-8375 
primary 'Rasool, B.'   2 ?                   
primary 'Akher, F.B.'  3 ?                   
primary 'Kutlesic, N.' 4 ?                   
primary 'Pant, S.'     5 ?                   
primary 'Boudker, O.'  6 ?                   
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Aspartate transporter' 43910.488 1 ? ? ? 
'C-terminal thrombin cleavage site, Twin-Strep tag, ALFA tag, and (HIS)10 tag. Engineered with loops and tails from NCBI KJS87745.1' 
2 non-polymer syn 'ASPARTIC ACID'         133.103   1 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSLYHKILIGFVLGVIVGLIFGDKAEFIKPLGDIFLRLLKMIVVPLVFSTIVTGIASMGDVKKLGRIGAKTLIYYMITTT
LAVTIGLILANIFKPGKGLSLGEIHEVAHPNAPSFTETLLNMIPTNPFEAMAEGNMLQIIVFAIFFGIALALMGEKAEPV
KKFFDSASEVMFKITDIVMKFAPYGVFALMAWTVGKYGLDVLAPLGKLILTVYLGCIIHILIVYTLLLRFLCKINPLRFF
KKIKEAMLVAFSTCSSAATLPVTMRVAEELGVPESIASFTLPLGATINMDGTALYQGVAAIFVAQAYGVELTLGQQLTIV
LTAVLASIGTAGVPGAGLVMLTMVLTSVGLPLEGIALIAGIDRILDMARTTVNVTGDLVATAIVARTENELNREMTATPL
EVLESKTIAL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSLYHKILIGFVLGVIVGLIFGDKAEFIKPLGDIFLRLLKMIVVPLVFSTIVTGIASMGDVKKLGRIGAKTLIYYMITTT
LAVTIGLILANIFKPGKGLSLGEIHEVAHPNAPSFTETLLNMIPTNPFEAMAEGNMLQIIVFAIFFGIALALMGEKAEPV
KKFFDSASEVMFKITDIVMKFAPYGVFALMAWTVGKYGLDVLAPLGKLILTVYLGCIIHILIVYTLLLRFLCKINPLRFF
KKIKEAMLVAFSTCSSAATLPVTMRVAEELGVPESIASFTLPLGATINMDGTALYQGVAAIFVAQAYGVELTLGQQLTIV
LTAVLASIGTAGVPGAGLVMLTMVLTSVGLPLEGIALIAGIDRILDMARTTVNVTGDLVATAIVARTENELNREMTATPL
EVLESKTIAL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'ASPARTIC ACID' 
_pdbx_entity_nonpoly.comp_id     ASP 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   LEU n 
1 4   TYR n 
1 5   HIS n 
1 6   LYS n 
1 7   ILE n 
1 8   LEU n 
1 9   ILE n 
1 10  GLY n 
1 11  PHE n 
1 12  VAL n 
1 13  LEU n 
1 14  GLY n 
1 15  VAL n 
1 16  ILE n 
1 17  VAL n 
1 18  GLY n 
1 19  LEU n 
1 20  ILE n 
1 21  PHE n 
1 22  GLY n 
1 23  ASP n 
1 24  LYS n 
1 25  ALA n 
1 26  GLU n 
1 27  PHE n 
1 28  ILE n 
1 29  LYS n 
1 30  PRO n 
1 31  LEU n 
1 32  GLY n 
1 33  ASP n 
1 34  ILE n 
1 35  PHE n 
1 36  LEU n 
1 37  ARG n 
1 38  LEU n 
1 39  LEU n 
1 40  LYS n 
1 41  MET n 
1 42  ILE n 
1 43  VAL n 
1 44  VAL n 
1 45  PRO n 
1 46  LEU n 
1 47  VAL n 
1 48  PHE n 
1 49  SER n 
1 50  THR n 
1 51  ILE n 
1 52  VAL n 
1 53  THR n 
1 54  GLY n 
1 55  ILE n 
1 56  ALA n 
1 57  SER n 
1 58  MET n 
1 59  GLY n 
1 60  ASP n 
1 61  VAL n 
1 62  LYS n 
1 63  LYS n 
1 64  LEU n 
1 65  GLY n 
1 66  ARG n 
1 67  ILE n 
1 68  GLY n 
1 69  ALA n 
1 70  LYS n 
1 71  THR n 
1 72  LEU n 
1 73  ILE n 
1 74  TYR n 
1 75  TYR n 
1 76  MET n 
1 77  ILE n 
1 78  THR n 
1 79  THR n 
1 80  THR n 
1 81  LEU n 
1 82  ALA n 
1 83  VAL n 
1 84  THR n 
1 85  ILE n 
1 86  GLY n 
1 87  LEU n 
1 88  ILE n 
1 89  LEU n 
1 90  ALA n 
1 91  ASN n 
1 92  ILE n 
1 93  PHE n 
1 94  LYS n 
1 95  PRO n 
1 96  GLY n 
1 97  LYS n 
1 98  GLY n 
1 99  LEU n 
1 100 SER n 
1 101 LEU n 
1 102 GLY n 
1 103 GLU n 
1 104 ILE n 
1 105 HIS n 
1 106 GLU n 
1 107 VAL n 
1 108 ALA n 
1 109 HIS n 
1 110 PRO n 
1 111 ASN n 
1 112 ALA n 
1 113 PRO n 
1 114 SER n 
1 115 PHE n 
1 116 THR n 
1 117 GLU n 
1 118 THR n 
1 119 LEU n 
1 120 LEU n 
1 121 ASN n 
1 122 MET n 
1 123 ILE n 
1 124 PRO n 
1 125 THR n 
1 126 ASN n 
1 127 PRO n 
1 128 PHE n 
1 129 GLU n 
1 130 ALA n 
1 131 MET n 
1 132 ALA n 
1 133 GLU n 
1 134 GLY n 
1 135 ASN n 
1 136 MET n 
1 137 LEU n 
1 138 GLN n 
1 139 ILE n 
1 140 ILE n 
1 141 VAL n 
1 142 PHE n 
1 143 ALA n 
1 144 ILE n 
1 145 PHE n 
1 146 PHE n 
1 147 GLY n 
1 148 ILE n 
1 149 ALA n 
1 150 LEU n 
1 151 ALA n 
1 152 LEU n 
1 153 MET n 
1 154 GLY n 
1 155 GLU n 
1 156 LYS n 
1 157 ALA n 
1 158 GLU n 
1 159 PRO n 
1 160 VAL n 
1 161 LYS n 
1 162 LYS n 
1 163 PHE n 
1 164 PHE n 
1 165 ASP n 
1 166 SER n 
1 167 ALA n 
1 168 SER n 
1 169 GLU n 
1 170 VAL n 
1 171 MET n 
1 172 PHE n 
1 173 LYS n 
1 174 ILE n 
1 175 THR n 
1 176 ASP n 
1 177 ILE n 
1 178 VAL n 
1 179 MET n 
1 180 LYS n 
1 181 PHE n 
1 182 ALA n 
1 183 PRO n 
1 184 TYR n 
1 185 GLY n 
1 186 VAL n 
1 187 PHE n 
1 188 ALA n 
1 189 LEU n 
1 190 MET n 
1 191 ALA n 
1 192 TRP n 
1 193 THR n 
1 194 VAL n 
1 195 GLY n 
1 196 LYS n 
1 197 TYR n 
1 198 GLY n 
1 199 LEU n 
1 200 ASP n 
1 201 VAL n 
1 202 LEU n 
1 203 ALA n 
1 204 PRO n 
1 205 LEU n 
1 206 GLY n 
1 207 LYS n 
1 208 LEU n 
1 209 ILE n 
1 210 LEU n 
1 211 THR n 
1 212 VAL n 
1 213 TYR n 
1 214 LEU n 
1 215 GLY n 
1 216 CYS n 
1 217 ILE n 
1 218 ILE n 
1 219 HIS n 
1 220 ILE n 
1 221 LEU n 
1 222 ILE n 
1 223 VAL n 
1 224 TYR n 
1 225 THR n 
1 226 LEU n 
1 227 LEU n 
1 228 LEU n 
1 229 ARG n 
1 230 PHE n 
1 231 LEU n 
1 232 CYS n 
1 233 LYS n 
1 234 ILE n 
1 235 ASN n 
1 236 PRO n 
1 237 LEU n 
1 238 ARG n 
1 239 PHE n 
1 240 PHE n 
1 241 LYS n 
1 242 LYS n 
1 243 ILE n 
1 244 LYS n 
1 245 GLU n 
1 246 ALA n 
1 247 MET n 
1 248 LEU n 
1 249 VAL n 
1 250 ALA n 
1 251 PHE n 
1 252 SER n 
1 253 THR n 
1 254 CYS n 
1 255 SER n 
1 256 SER n 
1 257 ALA n 
1 258 ALA n 
1 259 THR n 
1 260 LEU n 
1 261 PRO n 
1 262 VAL n 
1 263 THR n 
1 264 MET n 
1 265 ARG n 
1 266 VAL n 
1 267 ALA n 
1 268 GLU n 
1 269 GLU n 
1 270 LEU n 
1 271 GLY n 
1 272 VAL n 
1 273 PRO n 
1 274 GLU n 
1 275 SER n 
1 276 ILE n 
1 277 ALA n 
1 278 SER n 
1 279 PHE n 
1 280 THR n 
1 281 LEU n 
1 282 PRO n 
1 283 LEU n 
1 284 GLY n 
1 285 ALA n 
1 286 THR n 
1 287 ILE n 
1 288 ASN n 
1 289 MET n 
1 290 ASP n 
1 291 GLY n 
1 292 THR n 
1 293 ALA n 
1 294 LEU n 
1 295 TYR n 
1 296 GLN n 
1 297 GLY n 
1 298 VAL n 
1 299 ALA n 
1 300 ALA n 
1 301 ILE n 
1 302 PHE n 
1 303 VAL n 
1 304 ALA n 
1 305 GLN n 
1 306 ALA n 
1 307 TYR n 
1 308 GLY n 
1 309 VAL n 
1 310 GLU n 
1 311 LEU n 
1 312 THR n 
1 313 LEU n 
1 314 GLY n 
1 315 GLN n 
1 316 GLN n 
1 317 LEU n 
1 318 THR n 
1 319 ILE n 
1 320 VAL n 
1 321 LEU n 
1 322 THR n 
1 323 ALA n 
1 324 VAL n 
1 325 LEU n 
1 326 ALA n 
1 327 SER n 
1 328 ILE n 
1 329 GLY n 
1 330 THR n 
1 331 ALA n 
1 332 GLY n 
1 333 VAL n 
1 334 PRO n 
1 335 GLY n 
1 336 ALA n 
1 337 GLY n 
1 338 LEU n 
1 339 VAL n 
1 340 MET n 
1 341 LEU n 
1 342 THR n 
1 343 MET n 
1 344 VAL n 
1 345 LEU n 
1 346 THR n 
1 347 SER n 
1 348 VAL n 
1 349 GLY n 
1 350 LEU n 
1 351 PRO n 
1 352 LEU n 
1 353 GLU n 
1 354 GLY n 
1 355 ILE n 
1 356 ALA n 
1 357 LEU n 
1 358 ILE n 
1 359 ALA n 
1 360 GLY n 
1 361 ILE n 
1 362 ASP n 
1 363 ARG n 
1 364 ILE n 
1 365 LEU n 
1 366 ASP n 
1 367 MET n 
1 368 ALA n 
1 369 ARG n 
1 370 THR n 
1 371 THR n 
1 372 VAL n 
1 373 ASN n 
1 374 VAL n 
1 375 THR n 
1 376 GLY n 
1 377 ASP n 
1 378 LEU n 
1 379 VAL n 
1 380 ALA n 
1 381 THR n 
1 382 ALA n 
1 383 ILE n 
1 384 VAL n 
1 385 ALA n 
1 386 ARG n 
1 387 THR n 
1 388 GLU n 
1 389 ASN n 
1 390 GLU n 
1 391 LEU n 
1 392 ASN n 
1 393 ARG n 
1 394 GLU n 
1 395 MET n 
1 396 THR n 
1 397 ALA n 
1 398 THR n 
1 399 PRO n 
1 400 LEU n 
1 401 GLU n 
1 402 VAL n 
1 403 LEU n 
1 404 GLU n 
1 405 SER n 
1 406 LYS n 
1 407 THR n 
1 408 ILE n 
1 409 ALA n 
1 410 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   410 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'synthetic construct' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     32630 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   SER 2   2   2   SER SER A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   TYR 4   4   4   TYR TYR A . n 
A 1 5   HIS 5   5   5   HIS HIS A . n 
A 1 6   LYS 6   6   6   LYS LYS A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  PHE 11  11  11  PHE PHE A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  GLY 14  14  14  GLY GLY A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  ILE 16  16  16  ILE ILE A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  ILE 20  20  20  ILE ILE A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  GLY 22  22  22  GLY GLY A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  PRO 30  30  30  PRO PRO A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  PHE 35  35  35  PHE PHE A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LYS 40  40  40  LYS LYS A . n 
A 1 41  MET 41  41  41  MET MET A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  THR 53  53  53  THR THR A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  ILE 55  55  55  ILE ILE A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  MET 58  58  58  MET MET A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  ASP 60  60  60  ASP ASP A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  LYS 63  63  63  LYS LYS A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  GLY 68  68  68  GLY GLY A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  LYS 70  70  70  LYS LYS A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  MET 76  76  76  MET MET A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  THR 79  79  79  THR THR A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  GLY 86  86  86  GLY GLY A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  ILE 88  88  88  ILE ILE A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ASN 91  91  91  ASN ASN A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  LYS 94  94  94  LYS LYS A . n 
A 1 95  PRO 95  95  95  PRO PRO A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  GLY 98  98  98  GLY GLY A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 GLY 102 102 102 GLY GLY A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 ILE 104 104 104 ILE ILE A . n 
A 1 105 HIS 105 105 105 HIS HIS A . n 
A 1 106 GLU 106 106 106 GLU GLU A . n 
A 1 107 VAL 107 107 107 VAL VAL A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 HIS 109 109 109 HIS HIS A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 ASN 111 111 111 ASN ASN A . n 
A 1 112 ALA 112 112 112 ALA ALA A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 PHE 115 115 115 PHE PHE A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 THR 118 118 118 THR THR A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 ASN 121 121 121 ASN ASN A . n 
A 1 122 MET 122 122 122 MET MET A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 PRO 124 124 124 PRO PRO A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 ASN 126 126 126 ASN ASN A . n 
A 1 127 PRO 127 127 127 PRO PRO A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 MET 131 131 131 MET MET A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 ILE 140 140 140 ILE ILE A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 PHE 145 145 145 PHE PHE A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 MET 153 153 153 MET MET A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 LYS 156 156 156 LYS LYS A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 GLU 158 158 158 GLU GLU A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 LYS 161 161 161 LYS LYS A . n 
A 1 162 LYS 162 162 162 LYS LYS A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 PHE 164 164 164 PHE PHE A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 MET 171 171 171 MET MET A . n 
A 1 172 PHE 172 172 172 PHE PHE A . n 
A 1 173 LYS 173 173 173 LYS LYS A . n 
A 1 174 ILE 174 174 174 ILE ILE A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LYS 180 180 180 LYS LYS A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 TYR 184 184 184 TYR TYR A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 PHE 187 187 187 PHE PHE A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 MET 190 190 190 MET MET A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 TRP 192 192 192 TRP TRP A . n 
A 1 193 THR 193 193 193 THR THR A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 TYR 197 197 197 TYR TYR A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 CYS 216 216 216 CYS CYS A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 HIS 219 219 219 HIS HIS A . n 
A 1 220 ILE 220 220 220 ILE ILE A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 TYR 224 224 224 TYR TYR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 CYS 232 232 232 CYS CYS A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 ASN 235 235 235 ASN ASN A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 LYS 241 241 241 LYS LYS A . n 
A 1 242 LYS 242 242 242 LYS LYS A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 LYS 244 244 244 LYS LYS A . n 
A 1 245 GLU 245 245 245 GLU GLU A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 MET 247 247 247 MET MET A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 CYS 254 254 254 CYS CYS A . n 
A 1 255 SER 255 255 255 SER SER A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 ARG 265 265 265 ARG ARG A . n 
A 1 266 VAL 266 266 266 VAL VAL A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 VAL 272 272 272 VAL VAL A . n 
A 1 273 PRO 273 273 273 PRO PRO A . n 
A 1 274 GLU 274 274 274 GLU GLU A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 MET 289 289 289 MET MET A . n 
A 1 290 ASP 290 290 290 ASP ASP A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 TYR 295 295 295 TYR TYR A . n 
A 1 296 GLN 296 296 296 GLN GLN A . n 
A 1 297 GLY 297 297 297 GLY GLY A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 GLN 305 305 305 GLN GLN A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 VAL 309 309 309 VAL VAL A . n 
A 1 310 GLU 310 310 310 GLU GLU A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 THR 312 312 312 THR THR A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 GLY 314 314 314 GLY GLY A . n 
A 1 315 GLN 315 315 315 GLN GLN A . n 
A 1 316 GLN 316 316 316 GLN GLN A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 VAL 320 320 320 VAL VAL A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 THR 322 322 322 THR THR A . n 
A 1 323 ALA 323 323 323 ALA ALA A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 ILE 328 328 328 ILE ILE A . n 
A 1 329 GLY 329 329 329 GLY GLY A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 ALA 331 331 331 ALA ALA A . n 
A 1 332 GLY 332 332 332 GLY GLY A . n 
A 1 333 VAL 333 333 333 VAL VAL A . n 
A 1 334 PRO 334 334 334 PRO PRO A . n 
A 1 335 GLY 335 335 335 GLY GLY A . n 
A 1 336 ALA 336 336 336 ALA ALA A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 VAL 339 339 339 VAL VAL A . n 
A 1 340 MET 340 340 340 MET MET A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 MET 343 343 343 MET MET A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 THR 346 346 346 THR THR A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 LEU 350 350 350 LEU LEU A . n 
A 1 351 PRO 351 351 351 PRO PRO A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 GLU 353 353 353 GLU GLU A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 ILE 355 355 355 ILE ILE A . n 
A 1 356 ALA 356 356 356 ALA ALA A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 ILE 358 358 358 ILE ILE A . n 
A 1 359 ALA 359 359 359 ALA ALA A . n 
A 1 360 GLY 360 360 360 GLY GLY A . n 
A 1 361 ILE 361 361 361 ILE ILE A . n 
A 1 362 ASP 362 362 362 ASP ASP A . n 
A 1 363 ARG 363 363 363 ARG ARG A . n 
A 1 364 ILE 364 364 364 ILE ILE A . n 
A 1 365 LEU 365 365 365 LEU LEU A . n 
A 1 366 ASP 366 366 366 ASP ASP A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 ARG 369 369 369 ARG ARG A . n 
A 1 370 THR 370 370 370 THR THR A . n 
A 1 371 THR 371 371 371 THR THR A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 ASN 373 373 373 ASN ASN A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 THR 375 375 375 THR THR A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 THR 381 381 381 THR THR A . n 
A 1 382 ALA 382 382 382 ALA ALA A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 ALA 385 385 385 ALA ALA A . n 
A 1 386 ARG 386 386 386 ARG ARG A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 ASN 389 389 389 ASN ASN A . n 
A 1 390 GLU 390 390 390 GLU GLU A . n 
A 1 391 LEU 391 391 ?   ?   ?   A . n 
A 1 392 ASN 392 392 ?   ?   ?   A . n 
A 1 393 ARG 393 393 ?   ?   ?   A . n 
A 1 394 GLU 394 394 ?   ?   ?   A . n 
A 1 395 MET 395 395 ?   ?   ?   A . n 
A 1 396 THR 396 396 ?   ?   ?   A . n 
A 1 397 ALA 397 397 ?   ?   ?   A . n 
A 1 398 THR 398 398 ?   ?   ?   A . n 
A 1 399 PRO 399 399 ?   ?   ?   A . n 
A 1 400 LEU 400 400 ?   ?   ?   A . n 
A 1 401 GLU 401 401 ?   ?   ?   A . n 
A 1 402 VAL 402 402 ?   ?   ?   A . n 
A 1 403 LEU 403 403 ?   ?   ?   A . n 
A 1 404 GLU 404 404 ?   ?   ?   A . n 
A 1 405 SER 405 405 ?   ?   ?   A . n 
A 1 406 LYS 406 406 ?   ?   ?   A . n 
A 1 407 THR 407 407 ?   ?   ?   A . n 
A 1 408 ILE 408 408 ?   ?   ?   A . n 
A 1 409 ALA 409 409 ?   ?   ?   A . n 
A 1 410 LEU 410 410 ?   ?   ?   A . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        ASP 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   ASP 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          ASP 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     1000 
_pdbx_nonpoly_scheme.auth_seq_num    1000 
_pdbx_nonpoly_scheme.pdb_mon_id      ASP 
_pdbx_nonpoly_scheme.auth_mon_id     ASP 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BH0 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BH0 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BH0 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9BH0 
_struct.title                        'Ancestral uncoupled aspartate transporter in complex with L-aspartate' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BH0 
_struct_keywords.text            'Transporter, ion-uncoupled, ancestral, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9BH0 
_struct_ref.pdbx_db_accession          9BH0 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9BH0 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 410 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9BH0 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  410 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       410 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 2   ? GLY A 22  ? SER A 2   GLY A 22  1 ? 21 
HELX_P HELX_P2  AA2 ASP A 23  ? PHE A 27  ? ASP A 23  PHE A 27  5 ? 5  
HELX_P HELX_P3  AA3 ILE A 28  ? GLY A 59  ? ILE A 28  GLY A 59  1 ? 32 
HELX_P HELX_P4  AA4 ASP A 60  ? LYS A 94  ? ASP A 60  LYS A 94  1 ? 35 
HELX_P HELX_P5  AA5 SER A 114 ? ASN A 121 ? SER A 114 ASN A 121 1 ? 8  
HELX_P HELX_P6  AA6 ASN A 126 ? GLY A 134 ? ASN A 126 GLY A 134 1 ? 9  
HELX_P HELX_P7  AA7 ASN A 135 ? GLY A 154 ? ASN A 135 GLY A 154 1 ? 20 
HELX_P HELX_P8  AA8 ALA A 157 ? LYS A 180 ? ALA A 157 LYS A 180 1 ? 24 
HELX_P HELX_P9  AA9 PHE A 181 ? TYR A 197 ? PHE A 181 TYR A 197 1 ? 17 
HELX_P HELX_P10 AB1 GLY A 198 ? ALA A 203 ? GLY A 198 ALA A 203 1 ? 6  
HELX_P HELX_P11 AB2 LEU A 205 ? VAL A 223 ? LEU A 205 VAL A 223 1 ? 19 
HELX_P HELX_P12 AB3 VAL A 223 ? PHE A 230 ? VAL A 223 PHE A 230 1 ? 8  
HELX_P HELX_P13 AB4 ASN A 235 ? CYS A 254 ? ASN A 235 CYS A 254 1 ? 20 
HELX_P HELX_P14 AB5 SER A 255 ? GLY A 271 ? SER A 255 GLY A 271 1 ? 17 
HELX_P HELX_P15 AB6 PRO A 273 ? ASN A 288 ? PRO A 273 ASN A 288 1 ? 16 
HELX_P HELX_P16 AB7 MET A 289 ? TYR A 307 ? MET A 289 TYR A 307 1 ? 19 
HELX_P HELX_P17 AB8 THR A 312 ? THR A 330 ? THR A 312 THR A 330 1 ? 19 
HELX_P HELX_P18 AB9 GLY A 335 ? GLY A 349 ? GLY A 335 GLY A 349 1 ? 15 
HELX_P HELX_P19 AC1 LEU A 352 ? GLY A 360 ? LEU A 352 GLY A 360 1 ? 9  
HELX_P HELX_P20 AC2 ILE A 361 ? GLU A 388 ? ILE A 361 GLU A 388 1 ? 28 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9BH0 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    SER 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     100 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             -160.64 
_pdbx_validate_torsion.psi             112.78 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BH0 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BH0 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.4 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               71731 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '20 mM HEPES, 100 mM NMDG-Cl, 1 mM L-Asp' 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Ancestral uncoupled aspartate transporter in complex with L-aspartate' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BH0 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             0900 
_em_imaging.nominal_defocus_max             2100 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9BH0 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BH0 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LEU 391 ? A LEU 391 
2  1 Y 1 A ASN 392 ? A ASN 392 
3  1 Y 1 A ARG 393 ? A ARG 393 
4  1 Y 1 A GLU 394 ? A GLU 394 
5  1 Y 1 A MET 395 ? A MET 395 
6  1 Y 1 A THR 396 ? A THR 396 
7  1 Y 1 A ALA 397 ? A ALA 397 
8  1 Y 1 A THR 398 ? A THR 398 
9  1 Y 1 A PRO 399 ? A PRO 399 
10 1 Y 1 A LEU 400 ? A LEU 400 
11 1 Y 1 A GLU 401 ? A GLU 401 
12 1 Y 1 A VAL 402 ? A VAL 402 
13 1 Y 1 A LEU 403 ? A LEU 403 
14 1 Y 1 A GLU 404 ? A GLU 404 
15 1 Y 1 A SER 405 ? A SER 405 
16 1 Y 1 A LYS 406 ? A LYS 406 
17 1 Y 1 A THR 407 ? A THR 407 
18 1 Y 1 A ILE 408 ? A ILE 408 
19 1 Y 1 A ALA 409 ? A ALA 409 
20 1 Y 1 A LEU 410 ? A LEU 410 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-19 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BH0 
_em_admin.last_update        2025-03-12 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Ancestral uncoupled aspartate transporter in complex with L-aspartate' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          53953 
_em_entity_assembly_naturalsource.organism             'Pyrococcus horikoshii' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          316385 
_em_entity_assembly_recombinant.organism             'Escherichia coli str. K-12 substr. DH10B' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         58.00 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ? ? 
MASKING                    ? 3  ? ? ? ? ? 
'CTF CORRECTION'           ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ? ? 
'MODEL FITTING'            ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'         ? 8  ? ? ? ? ? 
OTHER                      ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ? ? 
CLASSIFICATION             ? 12 1 ? ? ? ? 
RECONSTRUCTION             ? 13 1 ? ? ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)' 'United States' R37NS134865 1 
'National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)' 'United States' F32NS102325 2 
# 
_atom_sites.entry_id                    9BH0 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . MET A 1 1   ? 117.019 128.955 169.625 1.00 126.56 ? 1    MET A N   1 
ATOM   2    C CA  . MET A 1 1   ? 117.455 130.322 169.883 1.00 129.05 ? 1    MET A CA  1 
ATOM   3    C C   . MET A 1 1   ? 118.972 130.410 169.988 1.00 130.96 ? 1    MET A C   1 
ATOM   4    O O   . MET A 1 1   ? 119.548 131.488 169.850 1.00 130.28 ? 1    MET A O   1 
ATOM   5    C CB  . MET A 1 1   ? 116.809 130.855 171.165 1.00 128.76 ? 1    MET A CB  1 
ATOM   6    C CG  . MET A 1 1   ? 115.590 131.758 170.962 1.00 131.96 ? 1    MET A CG  1 
ATOM   7    S SD  . MET A 1 1   ? 115.760 132.998 169.658 1.00 139.53 ? 1    MET A SD  1 
ATOM   8    C CE  . MET A 1 1   ? 114.392 134.086 170.044 1.00 127.08 ? 1    MET A CE  1 
ATOM   9    N N   . SER A 1 2   ? 119.619 129.274 170.234 1.00 126.44 ? 2    SER A N   1 
ATOM   10   C CA  . SER A 1 2   ? 121.073 129.235 170.233 1.00 123.00 ? 2    SER A CA  1 
ATOM   11   C C   . SER A 1 2   ? 121.610 129.675 168.879 1.00 121.94 ? 2    SER A C   1 
ATOM   12   O O   . SER A 1 2   ? 121.036 129.365 167.832 1.00 120.16 ? 2    SER A O   1 
ATOM   13   C CB  . SER A 1 2   ? 121.570 127.829 170.565 1.00 120.51 ? 2    SER A CB  1 
ATOM   14   O OG  . SER A 1 2   ? 120.834 126.854 169.853 1.00 120.12 ? 2    SER A OG  1 
ATOM   15   N N   . LEU A 1 3   ? 122.725 130.405 168.914 1.00 113.22 ? 3    LEU A N   1 
ATOM   16   C CA  . LEU A 1 3   ? 123.241 131.040 167.707 1.00 117.49 ? 3    LEU A CA  1 
ATOM   17   C C   . LEU A 1 3   ? 123.399 130.042 166.568 1.00 114.44 ? 3    LEU A C   1 
ATOM   18   O O   . LEU A 1 3   ? 123.052 130.350 165.422 1.00 111.44 ? 3    LEU A O   1 
ATOM   19   C CB  . LEU A 1 3   ? 124.580 131.702 168.021 1.00 112.06 ? 3    LEU A CB  1 
ATOM   20   C CG  . LEU A 1 3   ? 125.317 132.473 166.927 1.00 110.48 ? 3    LEU A CG  1 
ATOM   21   C CD1 . LEU A 1 3   ? 124.372 133.126 165.935 1.00 106.84 ? 3    LEU A CD1 1 
ATOM   22   C CD2 . LEU A 1 3   ? 126.220 133.504 167.564 1.00 112.72 ? 3    LEU A CD2 1 
ATOM   23   N N   . TYR A 1 4   ? 123.893 128.838 166.861 1.00 104.53 ? 4    TYR A N   1 
ATOM   24   C CA  . TYR A 1 4   ? 124.126 127.871 165.796 1.00 101.46 ? 4    TYR A CA  1 
ATOM   25   C C   . TYR A 1 4   ? 122.838 127.553 165.049 1.00 107.96 ? 4    TYR A C   1 
ATOM   26   O O   . TYR A 1 4   ? 122.814 127.541 163.813 1.00 114.04 ? 4    TYR A O   1 
ATOM   27   C CB  . TYR A 1 4   ? 124.730 126.592 166.364 1.00 102.02 ? 4    TYR A CB  1 
ATOM   28   C CG  . TYR A 1 4   ? 124.775 125.481 165.352 1.00 101.39 ? 4    TYR A CG  1 
ATOM   29   C CD1 . TYR A 1 4   ? 125.618 125.550 164.253 1.00 99.15  ? 4    TYR A CD1 1 
ATOM   30   C CD2 . TYR A 1 4   ? 123.940 124.383 165.469 1.00 105.84 ? 4    TYR A CD2 1 
ATOM   31   C CE1 . TYR A 1 4   ? 125.653 124.540 163.320 1.00 99.63  ? 4    TYR A CE1 1 
ATOM   32   C CE2 . TYR A 1 4   ? 123.963 123.373 164.539 1.00 107.71 ? 4    TYR A CE2 1 
ATOM   33   C CZ  . TYR A 1 4   ? 124.821 123.455 163.467 1.00 105.63 ? 4    TYR A CZ  1 
ATOM   34   O OH  . TYR A 1 4   ? 124.847 122.445 162.536 1.00 114.46 ? 4    TYR A OH  1 
ATOM   35   N N   . HIS A 1 5   ? 121.749 127.308 165.781 1.00 111.49 ? 5    HIS A N   1 
ATOM   36   C CA  . HIS A 1 5   ? 120.486 126.995 165.124 1.00 108.36 ? 5    HIS A CA  1 
ATOM   37   C C   . HIS A 1 5   ? 120.000 128.152 164.264 1.00 110.90 ? 5    HIS A C   1 
ATOM   38   O O   . HIS A 1 5   ? 119.433 127.927 163.190 1.00 115.11 ? 5    HIS A O   1 
ATOM   39   C CB  . HIS A 1 5   ? 119.431 126.619 166.163 1.00 106.43 ? 5    HIS A CB  1 
ATOM   40   C CG  . HIS A 1 5   ? 119.664 125.286 166.801 1.00 110.91 ? 5    HIS A CG  1 
ATOM   41   N ND1 . HIS A 1 5   ? 120.528 125.107 167.859 1.00 112.61 ? 5    HIS A ND1 1 
ATOM   42   C CD2 . HIS A 1 5   ? 119.149 124.065 166.526 1.00 110.86 ? 5    HIS A CD2 1 
ATOM   43   C CE1 . HIS A 1 5   ? 120.533 123.834 168.211 1.00 112.60 ? 5    HIS A CE1 1 
ATOM   44   N NE2 . HIS A 1 5   ? 119.704 123.180 167.417 1.00 113.57 ? 5    HIS A NE2 1 
ATOM   45   N N   . LYS A 1 6   ? 120.214 129.391 164.708 1.00 104.16 ? 6    LYS A N   1 
ATOM   46   C CA  . LYS A 1 6   ? 119.841 130.534 163.885 1.00 105.10 ? 6    LYS A CA  1 
ATOM   47   C C   . LYS A 1 6   ? 120.598 130.514 162.564 1.00 102.48 ? 6    LYS A C   1 
ATOM   48   O O   . LYS A 1 6   ? 120.019 130.752 161.498 1.00 110.31 ? 6    LYS A O   1 
ATOM   49   C CB  . LYS A 1 6   ? 120.102 131.835 164.644 1.00 107.60 ? 6    LYS A CB  1 
ATOM   50   C CG  . LYS A 1 6   ? 119.115 132.094 165.771 1.00 113.27 ? 6    LYS A CG  1 
ATOM   51   C CD  . LYS A 1 6   ? 119.177 133.534 166.256 1.00 116.08 ? 6    LYS A CD  1 
ATOM   52   C CE  . LYS A 1 6   ? 120.385 133.777 167.144 1.00 115.97 ? 6    LYS A CE  1 
ATOM   53   N NZ  . LYS A 1 6   ? 120.362 135.133 167.758 1.00 113.44 ? 6    LYS A NZ  1 
ATOM   54   N N   . ILE A 1 7   ? 121.898 130.216 162.613 1.00 90.16  ? 7    ILE A N   1 
ATOM   55   C CA  . ILE A 1 7   ? 122.663 130.065 161.379 1.00 97.31  ? 7    ILE A CA  1 
ATOM   56   C C   . ILE A 1 7   ? 122.099 128.919 160.552 1.00 97.86  ? 7    ILE A C   1 
ATOM   57   O O   . ILE A 1 7   ? 121.989 129.016 159.325 1.00 97.93  ? 7    ILE A O   1 
ATOM   58   C CB  . ILE A 1 7   ? 124.156 129.857 161.691 1.00 91.94  ? 7    ILE A CB  1 
ATOM   59   C CG1 . ILE A 1 7   ? 124.725 131.089 162.396 1.00 93.48  ? 7    ILE A CG1 1 
ATOM   60   C CG2 . ILE A 1 7   ? 124.931 129.574 160.410 1.00 86.28  ? 7    ILE A CG2 1 
ATOM   61   C CD1 . ILE A 1 7   ? 126.159 130.931 162.857 1.00 89.81  ? 7    ILE A CD1 1 
ATOM   62   N N   . LEU A 1 8   ? 121.741 127.813 161.205 1.00 101.62 ? 8    LEU A N   1 
ATOM   63   C CA  . LEU A 1 8   ? 121.175 126.680 160.481 1.00 95.54  ? 8    LEU A CA  1 
ATOM   64   C C   . LEU A 1 8   ? 119.835 127.038 159.850 1.00 97.24  ? 8    LEU A C   1 
ATOM   65   O O   . LEU A 1 8   ? 119.553 126.647 158.710 1.00 105.34 ? 8    LEU A O   1 
ATOM   66   C CB  . LEU A 1 8   ? 121.023 125.488 161.422 1.00 94.52  ? 8    LEU A CB  1 
ATOM   67   C CG  . LEU A 1 8   ? 120.487 124.202 160.798 1.00 92.49  ? 8    LEU A CG  1 
ATOM   68   C CD1 . LEU A 1 8   ? 121.324 123.791 159.602 1.00 97.17  ? 8    LEU A CD1 1 
ATOM   69   C CD2 . LEU A 1 8   ? 120.456 123.095 161.835 1.00 101.42 ? 8    LEU A CD2 1 
ATOM   70   N N   . ILE A 1 9   ? 118.990 127.767 160.581 1.00 98.56  ? 9    ILE A N   1 
ATOM   71   C CA  . ILE A 1 9   ? 117.708 128.185 160.023 1.00 97.57  ? 9    ILE A CA  1 
ATOM   72   C C   . ILE A 1 9   ? 117.929 129.079 158.814 1.00 101.15 ? 9    ILE A C   1 
ATOM   73   O O   . ILE A 1 9   ? 117.268 128.926 157.779 1.00 101.40 ? 9    ILE A O   1 
ATOM   74   C CB  . ILE A 1 9   ? 116.860 128.890 161.097 1.00 95.03  ? 9    ILE A CB  1 
ATOM   75   C CG1 . ILE A 1 9   ? 116.395 127.884 162.149 1.00 97.65  ? 9    ILE A CG1 1 
ATOM   76   C CG2 . ILE A 1 9   ? 115.665 129.577 160.459 1.00 98.46  ? 9    ILE A CG2 1 
ATOM   77   C CD1 . ILE A 1 9   ? 115.956 128.523 163.447 1.00 101.13 ? 9    ILE A CD1 1 
ATOM   78   N N   . GLY A 1 10  ? 118.852 130.034 158.927 1.00 102.88 ? 10   GLY A N   1 
ATOM   79   C CA  . GLY A 1 10  ? 119.165 130.873 157.785 1.00 98.99  ? 10   GLY A CA  1 
ATOM   80   C C   . GLY A 1 10  ? 119.657 130.065 156.601 1.00 96.83  ? 10   GLY A C   1 
ATOM   81   O O   . GLY A 1 10  ? 119.258 130.308 155.464 1.00 107.49 ? 10   GLY A O   1 
ATOM   82   N N   . PHE A 1 11  ? 120.519 129.083 156.859 1.00 83.49  ? 11   PHE A N   1 
ATOM   83   C CA  . PHE A 1 11  ? 121.030 128.223 155.798 1.00 89.83  ? 11   PHE A CA  1 
ATOM   84   C C   . PHE A 1 11  ? 119.889 127.521 155.070 1.00 89.18  ? 11   PHE A C   1 
ATOM   85   O O   . PHE A 1 11  ? 119.790 127.570 153.836 1.00 91.36  ? 11   PHE A O   1 
ATOM   86   C CB  . PHE A 1 11  ? 121.988 127.203 156.416 1.00 93.01  ? 11   PHE A CB  1 
ATOM   87   C CG  . PHE A 1 11  ? 122.662 126.303 155.427 1.00 87.56  ? 11   PHE A CG  1 
ATOM   88   C CD1 . PHE A 1 11  ? 123.905 126.626 154.917 1.00 84.68  ? 11   PHE A CD1 1 
ATOM   89   C CD2 . PHE A 1 11  ? 122.061 125.129 155.016 1.00 90.24  ? 11   PHE A CD2 1 
ATOM   90   C CE1 . PHE A 1 11  ? 124.536 125.793 154.022 1.00 87.56  ? 11   PHE A CE1 1 
ATOM   91   C CE2 . PHE A 1 11  ? 122.686 124.296 154.113 1.00 94.62  ? 11   PHE A CE2 1 
ATOM   92   C CZ  . PHE A 1 11  ? 123.924 124.631 153.613 1.00 92.82  ? 11   PHE A CZ  1 
ATOM   93   N N   . VAL A 1 12  ? 119.006 126.871 155.829 1.00 93.81  ? 12   VAL A N   1 
ATOM   94   C CA  . VAL A 1 12  ? 117.931 126.093 155.218 1.00 96.16  ? 12   VAL A CA  1 
ATOM   95   C C   . VAL A 1 12  ? 116.981 127.003 154.451 1.00 90.58  ? 12   VAL A C   1 
ATOM   96   O O   . VAL A 1 12  ? 116.582 126.697 153.318 1.00 99.01  ? 12   VAL A O   1 
ATOM   97   C CB  . VAL A 1 12  ? 117.189 125.277 156.291 1.00 97.79  ? 12   VAL A CB  1 
ATOM   98   C CG1 . VAL A 1 12  ? 115.964 124.604 155.691 1.00 95.53  ? 12   VAL A CG1 1 
ATOM   99   C CG2 . VAL A 1 12  ? 118.123 124.247 156.908 1.00 97.32  ? 12   VAL A CG2 1 
ATOM   100  N N   . LEU A 1 13  ? 116.597 128.132 155.049 1.00 89.95  ? 13   LEU A N   1 
ATOM   101  C CA  . LEU A 1 13  ? 115.660 129.019 154.372 1.00 100.41 ? 13   LEU A CA  1 
ATOM   102  C C   . LEU A 1 13  ? 116.288 129.659 153.143 1.00 108.78 ? 13   LEU A C   1 
ATOM   103  O O   . LEU A 1 13  ? 115.594 129.892 152.149 1.00 115.64 ? 13   LEU A O   1 
ATOM   104  C CB  . LEU A 1 13  ? 115.151 130.090 155.336 1.00 100.37 ? 13   LEU A CB  1 
ATOM   105  C CG  . LEU A 1 13  ? 114.394 129.594 156.573 1.00 101.21 ? 13   LEU A CG  1 
ATOM   106  C CD1 . LEU A 1 13  ? 113.477 130.684 157.100 1.00 99.62  ? 13   LEU A CD1 1 
ATOM   107  C CD2 . LEU A 1 13  ? 113.602 128.324 156.288 1.00 103.03 ? 13   LEU A CD2 1 
ATOM   108  N N   . GLY A 1 14  ? 117.590 129.940 153.178 1.00 112.11 ? 14   GLY A N   1 
ATOM   109  C CA  . GLY A 1 14  ? 118.255 130.429 151.985 1.00 109.41 ? 14   GLY A CA  1 
ATOM   110  C C   . GLY A 1 14  ? 118.262 129.399 150.876 1.00 110.17 ? 14   GLY A C   1 
ATOM   111  O O   . GLY A 1 14  ? 118.050 129.729 149.707 1.00 114.65 ? 14   GLY A O   1 
ATOM   112  N N   . VAL A 1 15  ? 118.500 128.134 151.226 1.00 100.00 ? 15   VAL A N   1 
ATOM   113  C CA  . VAL A 1 15  ? 118.434 127.076 150.222 1.00 103.36 ? 15   VAL A CA  1 
ATOM   114  C C   . VAL A 1 15  ? 117.039 127.026 149.610 1.00 103.26 ? 15   VAL A C   1 
ATOM   115  O O   . VAL A 1 15  ? 116.876 126.935 148.386 1.00 97.98  ? 15   VAL A O   1 
ATOM   116  C CB  . VAL A 1 15  ? 118.826 125.722 150.839 1.00 100.42 ? 15   VAL A CB  1 
ATOM   117  C CG1 . VAL A 1 15  ? 118.532 124.590 149.868 1.00 100.88 ? 15   VAL A CG1 1 
ATOM   118  C CG2 . VAL A 1 15  ? 120.293 125.724 151.232 1.00 102.18 ? 15   VAL A CG2 1 
ATOM   119  N N   . ILE A 1 16  ? 116.011 127.093 150.456 1.00 101.45 ? 16   ILE A N   1 
ATOM   120  C CA  . ILE A 1 16  ? 114.637 127.031 149.961 1.00 95.60  ? 16   ILE A CA  1 
ATOM   121  C C   . ILE A 1 16  ? 114.359 128.202 149.026 1.00 100.23 ? 16   ILE A C   1 
ATOM   122  O O   . ILE A 1 16  ? 113.801 128.032 147.933 1.00 106.80 ? 16   ILE A O   1 
ATOM   123  C CB  . ILE A 1 16  ? 113.646 127.003 151.138 1.00 99.53  ? 16   ILE A CB  1 
ATOM   124  C CG1 . ILE A 1 16  ? 113.633 125.618 151.786 1.00 102.86 ? 16   ILE A CG1 1 
ATOM   125  C CG2 . ILE A 1 16  ? 112.249 127.384 150.671 1.00 104.33 ? 16   ILE A CG2 1 
ATOM   126  C CD1 . ILE A 1 16  ? 113.057 125.606 153.184 1.00 105.08 ? 16   ILE A CD1 1 
ATOM   127  N N   . VAL A 1 17  ? 114.747 129.408 149.439 1.00 106.09 ? 17   VAL A N   1 
ATOM   128  C CA  . VAL A 1 17  ? 114.484 130.591 148.628 1.00 107.94 ? 17   VAL A CA  1 
ATOM   129  C C   . VAL A 1 17  ? 115.195 130.480 147.289 1.00 108.78 ? 17   VAL A C   1 
ATOM   130  O O   . VAL A 1 17  ? 114.615 130.766 146.234 1.00 107.08 ? 17   VAL A O   1 
ATOM   131  C CB  . VAL A 1 17  ? 114.902 131.863 149.389 1.00 109.51 ? 17   VAL A CB  1 
ATOM   132  C CG1 . VAL A 1 17  ? 114.938 133.060 148.454 1.00 108.27 ? 17   VAL A CG1 1 
ATOM   133  C CG2 . VAL A 1 17  ? 113.959 132.118 150.554 1.00 110.22 ? 17   VAL A CG2 1 
ATOM   134  N N   . GLY A 1 18  ? 116.460 130.060 147.305 1.00 114.06 ? 18   GLY A N   1 
ATOM   135  C CA  . GLY A 1 18  ? 117.178 129.877 146.056 1.00 117.10 ? 18   GLY A CA  1 
ATOM   136  C C   . GLY A 1 18  ? 116.497 128.876 145.147 1.00 116.26 ? 18   GLY A C   1 
ATOM   137  O O   . GLY A 1 18  ? 116.417 129.077 143.932 1.00 114.19 ? 18   GLY A O   1 
ATOM   138  N N   . LEU A 1 19  ? 115.989 127.784 145.721 1.00 114.57 ? 19   LEU A N   1 
ATOM   139  C CA  . LEU A 1 19  ? 115.266 126.807 144.915 1.00 111.42 ? 19   LEU A CA  1 
ATOM   140  C C   . LEU A 1 19  ? 114.020 127.423 144.295 1.00 108.73 ? 19   LEU A C   1 
ATOM   141  O O   . LEU A 1 19  ? 113.706 127.161 143.129 1.00 109.54 ? 19   LEU A O   1 
ATOM   142  C CB  . LEU A 1 19  ? 114.894 125.594 145.766 1.00 111.79 ? 19   LEU A CB  1 
ATOM   143  C CG  . LEU A 1 19  ? 115.997 124.566 146.027 1.00 109.81 ? 19   LEU A CG  1 
ATOM   144  C CD1 . LEU A 1 19  ? 115.450 123.405 146.838 1.00 111.92 ? 19   LEU A CD1 1 
ATOM   145  C CD2 . LEU A 1 19  ? 116.604 124.062 144.727 1.00 108.04 ? 19   LEU A CD2 1 
ATOM   146  N N   . ILE A 1 20  ? 113.298 128.247 145.056 1.00 111.33 ? 20   ILE A N   1 
ATOM   147  C CA  . ILE A 1 20  ? 112.051 128.810 144.548 1.00 111.39 ? 20   ILE A CA  1 
ATOM   148  C C   . ILE A 1 20  ? 112.331 129.815 143.437 1.00 113.00 ? 20   ILE A C   1 
ATOM   149  O O   . ILE A 1 20  ? 111.852 129.664 142.308 1.00 111.47 ? 20   ILE A O   1 
ATOM   150  C CB  . ILE A 1 20  ? 111.245 129.448 145.695 1.00 112.64 ? 20   ILE A CB  1 
ATOM   151  C CG1 . ILE A 1 20  ? 110.400 128.382 146.394 1.00 113.88 ? 20   ILE A CG1 1 
ATOM   152  C CG2 . ILE A 1 20  ? 110.346 130.565 145.165 1.00 111.06 ? 20   ILE A CG2 1 
ATOM   153  C CD1 . ILE A 1 20  ? 109.682 128.877 147.633 1.00 116.73 ? 20   ILE A CD1 1 
ATOM   154  N N   . PHE A 1 21  ? 113.111 130.852 143.736 1.00 122.45 ? 21   PHE A N   1 
ATOM   155  C CA  . PHE A 1 21  ? 113.297 131.963 142.813 1.00 125.29 ? 21   PHE A CA  1 
ATOM   156  C C   . PHE A 1 21  ? 114.392 131.722 141.783 1.00 124.22 ? 21   PHE A C   1 
ATOM   157  O O   . PHE A 1 21  ? 114.449 132.449 140.785 1.00 119.20 ? 21   PHE A O   1 
ATOM   158  C CB  . PHE A 1 21  ? 113.605 133.242 143.593 1.00 124.40 ? 21   PHE A CB  1 
ATOM   159  C CG  . PHE A 1 21  ? 112.452 133.735 144.416 1.00 123.27 ? 21   PHE A CG  1 
ATOM   160  C CD1 . PHE A 1 21  ? 111.449 134.494 143.841 1.00 120.54 ? 21   PHE A CD1 1 
ATOM   161  C CD2 . PHE A 1 21  ? 112.367 133.432 145.762 1.00 124.09 ? 21   PHE A CD2 1 
ATOM   162  C CE1 . PHE A 1 21  ? 110.386 134.946 144.595 1.00 123.30 ? 21   PHE A CE1 1 
ATOM   163  C CE2 . PHE A 1 21  ? 111.306 133.880 146.521 1.00 125.08 ? 21   PHE A CE2 1 
ATOM   164  C CZ  . PHE A 1 21  ? 110.315 134.638 145.937 1.00 125.62 ? 21   PHE A CZ  1 
ATOM   165  N N   . GLY A 1 22  ? 115.258 130.737 141.996 1.00 128.51 ? 22   GLY A N   1 
ATOM   166  C CA  . GLY A 1 22  ? 116.240 130.400 140.978 1.00 129.91 ? 22   GLY A CA  1 
ATOM   167  C C   . GLY A 1 22  ? 117.110 131.588 140.616 1.00 127.31 ? 22   GLY A C   1 
ATOM   168  O O   . GLY A 1 22  ? 117.705 132.241 141.479 1.00 129.25 ? 22   GLY A O   1 
ATOM   169  N N   . ASP A 1 23  ? 117.172 131.883 139.318 1.00 125.31 ? 23   ASP A N   1 
ATOM   170  C CA  . ASP A 1 23  ? 118.063 132.910 138.787 1.00 127.14 ? 23   ASP A CA  1 
ATOM   171  C C   . ASP A 1 23  ? 117.854 134.238 139.504 1.00 131.06 ? 23   ASP A C   1 
ATOM   172  O O   . ASP A 1 23  ? 118.812 134.980 139.739 1.00 127.87 ? 23   ASP A O   1 
ATOM   173  C CB  . ASP A 1 23  ? 117.832 133.063 137.279 1.00 129.98 ? 23   ASP A CB  1 
ATOM   174  C CG  . ASP A 1 23  ? 118.777 134.063 136.627 1.00 128.80 ? 23   ASP A CG  1 
ATOM   175  O OD1 . ASP A 1 23  ? 119.124 133.852 135.447 1.00 126.95 ? 23   ASP A OD1 1 
ATOM   176  O OD2 . ASP A 1 23  ? 119.167 135.058 137.272 1.00 125.42 ? 23   ASP A OD2 1 
ATOM   177  N N   . LYS A 1 24  ? 116.609 134.539 139.877 1.00 126.89 ? 24   LYS A N   1 
ATOM   178  C CA  . LYS A 1 24  ? 116.302 135.821 140.499 1.00 124.89 ? 24   LYS A CA  1 
ATOM   179  C C   . LYS A 1 24  ? 116.920 135.975 141.882 1.00 118.81 ? 24   LYS A C   1 
ATOM   180  O O   . LYS A 1 24  ? 116.909 137.085 142.423 1.00 114.40 ? 24   LYS A O   1 
ATOM   181  C CB  . LYS A 1 24  ? 114.785 136.005 140.592 1.00 122.52 ? 24   LYS A CB  1 
ATOM   182  C CG  . LYS A 1 24  ? 114.143 136.600 139.344 1.00 123.30 ? 24   LYS A CG  1 
ATOM   183  C CD  . LYS A 1 24  ? 114.444 135.786 138.095 1.00 119.38 ? 24   LYS A CD  1 
ATOM   184  C CE  . LYS A 1 24  ? 113.860 136.440 136.855 1.00 120.97 ? 24   LYS A CE  1 
ATOM   185  N NZ  . LYS A 1 24  ? 114.313 135.772 135.605 1.00 120.55 ? 24   LYS A NZ  1 
ATOM   186  N N   . ALA A 1 25  ? 117.461 134.903 142.461 1.00 114.27 ? 25   ALA A N   1 
ATOM   187  C CA  . ALA A 1 25  ? 118.011 134.973 143.809 1.00 115.22 ? 25   ALA A CA  1 
ATOM   188  C C   . ALA A 1 25  ? 119.229 135.880 143.907 1.00 115.48 ? 25   ALA A C   1 
ATOM   189  O O   . ALA A 1 25  ? 119.618 136.241 145.022 1.00 116.00 ? 25   ALA A O   1 
ATOM   190  C CB  . ALA A 1 25  ? 118.383 133.575 144.296 1.00 114.69 ? 25   ALA A CB  1 
ATOM   191  N N   . GLU A 1 26  ? 119.838 136.257 142.782 1.00 119.56 ? 26   GLU A N   1 
ATOM   192  C CA  . GLU A 1 26  ? 121.002 137.133 142.826 1.00 121.15 ? 26   GLU A CA  1 
ATOM   193  C C   . GLU A 1 26  ? 120.672 138.474 143.464 1.00 122.03 ? 26   GLU A C   1 
ATOM   194  O O   . GLU A 1 26  ? 121.573 139.114 144.018 1.00 123.44 ? 26   GLU A O   1 
ATOM   195  C CB  . GLU A 1 26  ? 121.562 137.271 141.396 1.00 121.70 ? 26   GLU A CB  1 
ATOM   196  C CG  . GLU A 1 26  ? 122.749 138.235 141.125 1.00 123.51 ? 26   GLU A CG  1 
ATOM   197  C CD  . GLU A 1 26  ? 122.553 139.682 141.550 1.00 128.09 ? 26   GLU A CD  1 
ATOM   198  O OE1 . GLU A 1 26  ? 121.396 140.146 141.627 1.00 129.30 ? 26   GLU A OE1 1 
ATOM   199  O OE2 . GLU A 1 26  ? 123.568 140.365 141.796 1.00 126.13 ? 26   GLU A OE2 1 
ATOM   200  N N   . PHE A 1 27  ? 119.405 138.894 143.433 1.00 114.87 ? 27   PHE A N   1 
ATOM   201  C CA  . PHE A 1 27  ? 119.028 140.179 144.012 1.00 113.51 ? 27   PHE A CA  1 
ATOM   202  C C   . PHE A 1 27  ? 119.537 140.314 145.441 1.00 117.11 ? 27   PHE A C   1 
ATOM   203  O O   . PHE A 1 27  ? 119.986 141.391 145.849 1.00 119.54 ? 27   PHE A O   1 
ATOM   204  C CB  . PHE A 1 27  ? 117.508 140.340 143.969 1.00 114.61 ? 27   PHE A CB  1 
ATOM   205  C CG  . PHE A 1 27  ? 117.005 141.553 144.695 1.00 117.74 ? 27   PHE A CG  1 
ATOM   206  C CD1 . PHE A 1 27  ? 116.893 142.769 144.045 1.00 121.60 ? 27   PHE A CD1 1 
ATOM   207  C CD2 . PHE A 1 27  ? 116.635 141.473 146.026 1.00 117.13 ? 27   PHE A CD2 1 
ATOM   208  C CE1 . PHE A 1 27  ? 116.428 143.885 144.712 1.00 122.76 ? 27   PHE A CE1 1 
ATOM   209  C CE2 . PHE A 1 27  ? 116.170 142.585 146.698 1.00 120.36 ? 27   PHE A CE2 1 
ATOM   210  C CZ  . PHE A 1 27  ? 116.066 143.793 146.039 1.00 122.27 ? 27   PHE A CZ  1 
ATOM   211  N N   . ILE A 1 28  ? 119.477 139.230 146.220 1.00 109.33 ? 28   ILE A N   1 
ATOM   212  C CA  . ILE A 1 28  ? 119.918 139.274 147.612 1.00 104.53 ? 28   ILE A CA  1 
ATOM   213  C C   . ILE A 1 28  ? 121.409 139.018 147.767 1.00 104.71 ? 28   ILE A C   1 
ATOM   214  O O   . ILE A 1 28  ? 121.898 138.940 148.904 1.00 108.68 ? 28   ILE A O   1 
ATOM   215  C CB  . ILE A 1 28  ? 119.128 138.254 148.457 1.00 104.55 ? 28   ILE A CB  1 
ATOM   216  C CG1 . ILE A 1 28  ? 118.977 138.753 149.894 1.00 105.81 ? 28   ILE A CG1 1 
ATOM   217  C CG2 . ILE A 1 28  ? 119.804 136.890 148.437 1.00 102.99 ? 28   ILE A CG2 1 
ATOM   218  C CD1 . ILE A 1 28  ? 117.995 139.894 150.045 1.00 107.96 ? 28   ILE A CD1 1 
ATOM   219  N N   . LYS A 1 29  ? 122.149 138.889 146.669 1.00 104.45 ? 29   LYS A N   1 
ATOM   220  C CA  . LYS A 1 29  ? 123.577 138.602 146.766 1.00 105.82 ? 29   LYS A CA  1 
ATOM   221  C C   . LYS A 1 29  ? 124.345 139.630 147.585 1.00 102.05 ? 29   LYS A C   1 
ATOM   222  O O   . LYS A 1 29  ? 125.199 139.220 148.390 1.00 102.80 ? 29   LYS A O   1 
ATOM   223  C CB  . LYS A 1 29  ? 124.180 138.496 145.359 1.00 106.85 ? 29   LYS A CB  1 
ATOM   224  C CG  . LYS A 1 29  ? 125.592 137.936 145.339 1.00 101.25 ? 29   LYS A CG  1 
ATOM   225  C CD  . LYS A 1 29  ? 126.632 139.034 145.188 1.00 104.10 ? 29   LYS A CD  1 
ATOM   226  C CE  . LYS A 1 29  ? 126.728 139.518 143.751 1.00 107.66 ? 29   LYS A CE  1 
ATOM   227  N NZ  . LYS A 1 29  ? 127.777 140.561 143.580 1.00 109.86 ? 29   LYS A NZ  1 
ATOM   228  N N   . PRO A 1 30  ? 124.115 140.938 147.444 1.00 98.38  ? 30   PRO A N   1 
ATOM   229  C CA  . PRO A 1 30  ? 124.945 141.902 148.183 1.00 102.03 ? 30   PRO A CA  1 
ATOM   230  C C   . PRO A 1 30  ? 124.933 141.690 149.684 1.00 101.51 ? 30   PRO A C   1 
ATOM   231  O O   . PRO A 1 30  ? 125.951 141.939 150.341 1.00 112.44 ? 30   PRO A O   1 
ATOM   232  C CB  . PRO A 1 30  ? 124.331 143.255 147.800 1.00 104.58 ? 30   PRO A CB  1 
ATOM   233  C CG  . PRO A 1 30  ? 123.677 143.012 146.489 1.00 103.81 ? 30   PRO A CG  1 
ATOM   234  C CD  . PRO A 1 30  ? 123.147 141.614 146.565 1.00 105.09 ? 30   PRO A CD  1 
ATOM   235  N N   . LEU A 1 31  ? 123.816 141.233 150.250 1.00 81.09  ? 31   LEU A N   1 
ATOM   236  C CA  . LEU A 1 31  ? 123.761 141.034 151.693 1.00 85.61  ? 31   LEU A CA  1 
ATOM   237  C C   . LEU A 1 31  ? 124.822 140.049 152.163 1.00 93.66  ? 31   LEU A C   1 
ATOM   238  O O   . LEU A 1 31  ? 125.436 140.259 153.214 1.00 98.25  ? 31   LEU A O   1 
ATOM   239  C CB  . LEU A 1 31  ? 122.371 140.551 152.102 1.00 88.03  ? 31   LEU A CB  1 
ATOM   240  C CG  . LEU A 1 31  ? 122.061 140.620 153.596 1.00 91.03  ? 31   LEU A CG  1 
ATOM   241  C CD1 . LEU A 1 31  ? 121.882 142.059 154.042 1.00 95.10  ? 31   LEU A CD1 1 
ATOM   242  C CD2 . LEU A 1 31  ? 120.823 139.805 153.917 1.00 96.23  ? 31   LEU A CD2 1 
ATOM   243  N N   . GLY A 1 32  ? 125.056 138.981 151.407 1.00 100.22 ? 32   GLY A N   1 
ATOM   244  C CA  . GLY A 1 32  ? 126.101 138.036 151.747 1.00 103.56 ? 32   GLY A CA  1 
ATOM   245  C C   . GLY A 1 32  ? 127.482 138.644 151.625 1.00 99.91  ? 32   GLY A C   1 
ATOM   246  O O   . GLY A 1 32  ? 128.369 138.371 152.441 1.00 107.08 ? 32   GLY A O   1 
ATOM   247  N N   . ASP A 1 33  ? 127.677 139.472 150.598 1.00 94.50  ? 33   ASP A N   1 
ATOM   248  C CA  . ASP A 1 33  ? 128.965 140.130 150.421 1.00 94.55  ? 33   ASP A CA  1 
ATOM   249  C C   . ASP A 1 33  ? 129.314 140.979 151.634 1.00 94.32  ? 33   ASP A C   1 
ATOM   250  O O   . ASP A 1 33  ? 130.486 141.078 152.014 1.00 97.94  ? 33   ASP A O   1 
ATOM   251  C CB  . ASP A 1 33  ? 128.948 140.983 149.154 1.00 100.23 ? 33   ASP A CB  1 
ATOM   252  C CG  . ASP A 1 33  ? 129.088 140.156 147.895 1.00 108.78 ? 33   ASP A CG  1 
ATOM   253  O OD1 . ASP A 1 33  ? 129.188 140.748 146.801 1.00 108.59 ? 33   ASP A OD1 1 
ATOM   254  O OD2 . ASP A 1 33  ? 129.101 138.911 147.999 1.00 110.57 ? 33   ASP A OD2 1 
ATOM   255  N N   . ILE A 1 34  ? 128.312 141.598 152.257 1.00 82.12  ? 34   ILE A N   1 
ATOM   256  C CA  . ILE A 1 34  ? 128.566 142.366 153.472 1.00 81.98  ? 34   ILE A CA  1 
ATOM   257  C C   . ILE A 1 34  ? 129.100 141.454 154.566 1.00 91.18  ? 34   ILE A C   1 
ATOM   258  O O   . ILE A 1 34  ? 130.046 141.804 155.282 1.00 98.21  ? 34   ILE A O   1 
ATOM   259  C CB  . ILE A 1 34  ? 127.289 143.097 153.919 1.00 81.02  ? 34   ILE A CB  1 
ATOM   260  C CG1 . ILE A 1 34  ? 127.009 144.282 152.997 1.00 86.74  ? 34   ILE A CG1 1 
ATOM   261  C CG2 . ILE A 1 34  ? 127.423 143.564 155.358 1.00 86.04  ? 34   ILE A CG2 1 
ATOM   262  C CD1 . ILE A 1 34  ? 125.603 144.827 153.113 1.00 89.01  ? 34   ILE A CD1 1 
ATOM   263  N N   . PHE A 1 35  ? 128.501 140.273 154.716 1.00 89.34  ? 35   PHE A N   1 
ATOM   264  C CA  . PHE A 1 35  ? 128.974 139.324 155.717 1.00 86.61  ? 35   PHE A CA  1 
ATOM   265  C C   . PHE A 1 35  ? 130.407 138.895 155.435 1.00 92.20  ? 35   PHE A C   1 
ATOM   266  O O   . PHE A 1 35  ? 131.236 138.825 156.352 1.00 95.82  ? 35   PHE A O   1 
ATOM   267  C CB  . PHE A 1 35  ? 128.044 138.114 155.754 1.00 84.41  ? 35   PHE A CB  1 
ATOM   268  C CG  . PHE A 1 35  ? 128.456 137.063 156.735 1.00 81.23  ? 35   PHE A CG  1 
ATOM   269  C CD1 . PHE A 1 35  ? 128.657 137.379 158.064 1.00 86.36  ? 35   PHE A CD1 1 
ATOM   270  C CD2 . PHE A 1 35  ? 128.635 135.754 156.328 1.00 79.91  ? 35   PHE A CD2 1 
ATOM   271  C CE1 . PHE A 1 35  ? 129.034 136.411 158.968 1.00 93.19  ? 35   PHE A CE1 1 
ATOM   272  C CE2 . PHE A 1 35  ? 129.011 134.783 157.228 1.00 85.69  ? 35   PHE A CE2 1 
ATOM   273  C CZ  . PHE A 1 35  ? 129.209 135.111 158.550 1.00 91.28  ? 35   PHE A CZ  1 
ATOM   274  N N   . LEU A 1 36  ? 130.719 138.603 154.171 1.00 92.94  ? 36   LEU A N   1 
ATOM   275  C CA  . LEU A 1 36  ? 132.081 138.207 153.829 1.00 81.04  ? 36   LEU A CA  1 
ATOM   276  C C   . LEU A 1 36  ? 133.070 139.325 154.123 1.00 88.87  ? 36   LEU A C   1 
ATOM   277  O O   . LEU A 1 36  ? 134.157 139.078 154.657 1.00 100.36 ? 36   LEU A O   1 
ATOM   278  C CB  . LEU A 1 36  ? 132.159 137.803 152.358 1.00 85.19  ? 36   LEU A CB  1 
ATOM   279  C CG  . LEU A 1 36  ? 132.412 136.320 152.096 1.00 88.85  ? 36   LEU A CG  1 
ATOM   280  C CD1 . LEU A 1 36  ? 132.385 136.032 150.606 1.00 94.46  ? 36   LEU A CD1 1 
ATOM   281  C CD2 . LEU A 1 36  ? 133.742 135.900 152.695 1.00 88.15  ? 36   LEU A CD2 1 
ATOM   282  N N   . ARG A 1 37  ? 132.716 140.562 153.774 1.00 79.19  ? 37   ARG A N   1 
ATOM   283  C CA  . ARG A 1 37  ? 133.604 141.685 154.043 1.00 75.80  ? 37   ARG A CA  1 
ATOM   284  C C   . ARG A 1 37  ? 133.824 141.854 155.539 1.00 78.89  ? 37   ARG A C   1 
ATOM   285  O O   . ARG A 1 37  ? 134.955 142.076 155.990 1.00 92.45  ? 37   ARG A O   1 
ATOM   286  C CB  . ARG A 1 37  ? 133.023 142.962 153.438 1.00 72.39  ? 37   ARG A CB  1 
ATOM   287  C CG  . ARG A 1 37  ? 132.797 142.887 151.935 1.00 74.20  ? 37   ARG A CG  1 
ATOM   288  C CD  . ARG A 1 37  ? 133.860 143.643 151.161 1.00 74.63  ? 37   ARG A CD  1 
ATOM   289  N NE  . ARG A 1 37  ? 133.457 145.019 150.897 1.00 85.10  ? 37   ARG A NE  1 
ATOM   290  C CZ  . ARG A 1 37  ? 134.211 145.917 150.278 1.00 91.62  ? 37   ARG A CZ  1 
ATOM   291  N NH1 . ARG A 1 37  ? 135.425 145.619 149.844 1.00 90.91  ? 37   ARG A NH1 1 
ATOM   292  N NH2 . ARG A 1 37  ? 133.735 147.145 150.089 1.00 89.57  ? 37   ARG A NH2 1 
ATOM   293  N N   . LEU A 1 38  ? 132.755 141.739 156.327 1.00 70.94  ? 38   LEU A N   1 
ATOM   294  C CA  . LEU A 1 38  ? 132.896 141.866 157.771 1.00 78.77  ? 38   LEU A CA  1 
ATOM   295  C C   . LEU A 1 38  ? 133.796 140.779 158.338 1.00 82.38  ? 38   LEU A C   1 
ATOM   296  O O   . LEU A 1 38  ? 134.633 141.060 159.202 1.00 89.90  ? 38   LEU A O   1 
ATOM   297  C CB  . LEU A 1 38  ? 131.524 141.819 158.438 1.00 78.82  ? 38   LEU A CB  1 
ATOM   298  C CG  . LEU A 1 38  ? 130.665 143.072 158.271 1.00 78.40  ? 38   LEU A CG  1 
ATOM   299  C CD1 . LEU A 1 38  ? 129.265 142.826 158.798 1.00 82.52  ? 38   LEU A CD1 1 
ATOM   300  C CD2 . LEU A 1 38  ? 131.296 144.257 158.976 1.00 82.87  ? 38   LEU A CD2 1 
ATOM   301  N N   . LEU A 1 39  ? 133.647 139.538 157.872 1.00 79.98  ? 39   LEU A N   1 
ATOM   302  C CA  . LEU A 1 39  ? 134.519 138.474 158.357 1.00 79.55  ? 39   LEU A CA  1 
ATOM   303  C C   . LEU A 1 39  ? 135.968 138.732 157.964 1.00 80.65  ? 39   LEU A C   1 
ATOM   304  O O   . LEU A 1 39  ? 136.883 138.557 158.777 1.00 91.73  ? 39   LEU A O   1 
ATOM   305  C CB  . LEU A 1 39  ? 134.054 137.120 157.824 1.00 90.52  ? 39   LEU A CB  1 
ATOM   306  C CG  . LEU A 1 39  ? 132.893 136.451 158.560 1.00 85.45  ? 39   LEU A CG  1 
ATOM   307  C CD1 . LEU A 1 39  ? 132.642 135.075 157.978 1.00 88.10  ? 39   LEU A CD1 1 
ATOM   308  C CD2 . LEU A 1 39  ? 133.162 136.355 160.053 1.00 75.94  ? 39   LEU A CD2 1 
ATOM   309  N N   . LYS A 1 40  ? 136.199 139.156 156.720 1.00 71.12  ? 40   LYS A N   1 
ATOM   310  C CA  . LYS A 1 40  ? 137.561 139.444 156.285 1.00 72.80  ? 40   LYS A CA  1 
ATOM   311  C C   . LYS A 1 40  ? 138.180 140.554 157.121 1.00 84.78  ? 40   LYS A C   1 
ATOM   312  O O   . LYS A 1 40  ? 139.390 140.553 157.372 1.00 93.80  ? 40   LYS A O   1 
ATOM   313  C CB  . LYS A 1 40  ? 137.568 139.834 154.808 1.00 76.55  ? 40   LYS A CB  1 
ATOM   314  C CG  . LYS A 1 40  ? 137.428 138.669 153.850 1.00 74.48  ? 40   LYS A CG  1 
ATOM   315  C CD  . LYS A 1 40  ? 137.314 139.162 152.420 1.00 74.68  ? 40   LYS A CD  1 
ATOM   316  C CE  . LYS A 1 40  ? 137.246 138.013 151.434 1.00 80.21  ? 40   LYS A CE  1 
ATOM   317  N NZ  . LYS A 1 40  ? 137.059 138.498 150.040 1.00 82.70  ? 40   LYS A NZ  1 
ATOM   318  N N   . MET A 1 41  ? 137.360 141.510 157.562 1.00 86.18  ? 41   MET A N   1 
ATOM   319  C CA  . MET A 1 41  ? 137.883 142.652 158.305 1.00 80.20  ? 41   MET A CA  1 
ATOM   320  C C   . MET A 1 41  ? 138.681 142.210 159.527 1.00 89.36  ? 41   MET A C   1 
ATOM   321  O O   . MET A 1 41  ? 139.627 142.889 159.939 1.00 95.00  ? 41   MET A O   1 
ATOM   322  C CB  . MET A 1 41  ? 136.724 143.572 158.711 1.00 79.87  ? 41   MET A CB  1 
ATOM   323  C CG  . MET A 1 41  ? 136.835 144.216 160.093 1.00 85.83  ? 41   MET A CG  1 
ATOM   324  S SD  . MET A 1 41  ? 135.299 144.993 160.625 1.00 97.13  ? 41   MET A SD  1 
ATOM   325  C CE  . MET A 1 41  ? 135.040 146.189 159.320 1.00 95.03  ? 41   MET A CE  1 
ATOM   326  N N   . ILE A 1 42  ? 138.318 141.070 160.118 1.00 89.40  ? 42   ILE A N   1 
ATOM   327  C CA  . ILE A 1 42  ? 138.872 140.696 161.416 1.00 81.48  ? 42   ILE A CA  1 
ATOM   328  C C   . ILE A 1 42  ? 140.191 139.947 161.272 1.00 82.20  ? 42   ILE A C   1 
ATOM   329  O O   . ILE A 1 42  ? 141.028 139.979 162.181 1.00 88.38  ? 42   ILE A O   1 
ATOM   330  C CB  . ILE A 1 42  ? 137.841 139.852 162.185 1.00 80.67  ? 42   ILE A CB  1 
ATOM   331  C CG1 . ILE A 1 42  ? 136.532 140.628 162.324 1.00 85.93  ? 42   ILE A CG1 1 
ATOM   332  C CG2 . ILE A 1 42  ? 138.385 139.456 163.556 1.00 77.31  ? 42   ILE A CG2 1 
ATOM   333  C CD1 . ILE A 1 42  ? 135.599 140.082 163.376 1.00 87.25  ? 42   ILE A CD1 1 
ATOM   334  N N   . VAL A 1 43  ? 140.407 139.274 160.141 1.00 83.76  ? 43   VAL A N   1 
ATOM   335  C CA  . VAL A 1 43  ? 141.400 138.203 160.088 1.00 80.56  ? 43   VAL A CA  1 
ATOM   336  C C   . VAL A 1 43  ? 142.783 138.712 160.483 1.00 96.47  ? 43   VAL A C   1 
ATOM   337  O O   . VAL A 1 43  ? 143.362 138.262 161.479 1.00 110.63 ? 43   VAL A O   1 
ATOM   338  C CB  . VAL A 1 43  ? 141.415 137.560 158.691 1.00 78.32  ? 43   VAL A CB  1 
ATOM   339  C CG1 . VAL A 1 43  ? 142.333 136.349 158.674 1.00 87.70  ? 43   VAL A CG1 1 
ATOM   340  C CG2 . VAL A 1 43  ? 140.012 137.158 158.280 1.00 93.81  ? 43   VAL A CG2 1 
ATOM   341  N N   . VAL A 1 44  ? 143.337 139.651 159.716 1.00 85.19  ? 44   VAL A N   1 
ATOM   342  C CA  . VAL A 1 44  ? 144.751 139.996 159.881 1.00 85.03  ? 44   VAL A CA  1 
ATOM   343  C C   . VAL A 1 44  ? 145.055 140.492 161.290 1.00 85.87  ? 44   VAL A C   1 
ATOM   344  O O   . VAL A 1 44  ? 145.960 139.934 161.936 1.00 94.59  ? 44   VAL A O   1 
ATOM   345  C CB  . VAL A 1 44  ? 145.176 141.002 158.797 1.00 86.83  ? 44   VAL A CB  1 
ATOM   346  C CG1 . VAL A 1 44  ? 146.417 141.770 159.233 1.00 88.96  ? 44   VAL A CG1 1 
ATOM   347  C CG2 . VAL A 1 44  ? 145.422 140.284 157.478 1.00 89.35  ? 44   VAL A CG2 1 
ATOM   348  N N   . PRO A 1 45  ? 144.369 141.506 161.824 1.00 74.25  ? 45   PRO A N   1 
ATOM   349  C CA  . PRO A 1 45  ? 144.657 141.906 163.209 1.00 80.27  ? 45   PRO A CA  1 
ATOM   350  C C   . PRO A 1 45  ? 144.483 140.763 164.186 1.00 82.57  ? 45   PRO A C   1 
ATOM   351  O O   . PRO A 1 45  ? 145.306 140.587 165.094 1.00 85.57  ? 45   PRO A O   1 
ATOM   352  C CB  . PRO A 1 45  ? 143.650 143.034 163.466 1.00 79.01  ? 45   PRO A CB  1 
ATOM   353  C CG  . PRO A 1 45  ? 143.270 143.533 162.125 1.00 86.03  ? 45   PRO A CG  1 
ATOM   354  C CD  . PRO A 1 45  ? 143.345 142.361 161.201 1.00 76.08  ? 45   PRO A CD  1 
ATOM   355  N N   . LEU A 1 46  ? 143.430 139.964 164.007 1.00 80.22  ? 46   LEU A N   1 
ATOM   356  C CA  . LEU A 1 46  ? 143.218 138.819 164.880 1.00 68.37  ? 46   LEU A CA  1 
ATOM   357  C C   . LEU A 1 46  ? 144.368 137.834 164.772 1.00 67.98  ? 46   LEU A C   1 
ATOM   358  O O   . LEU A 1 46  ? 144.872 137.350 165.789 1.00 87.20  ? 46   LEU A O   1 
ATOM   359  C CB  . LEU A 1 46  ? 141.896 138.136 164.537 1.00 73.18  ? 46   LEU A CB  1 
ATOM   360  C CG  . LEU A 1 46  ? 141.547 136.896 165.359 1.00 76.28  ? 46   LEU A CG  1 
ATOM   361  C CD1 . LEU A 1 46  ? 141.125 137.291 166.761 1.00 80.72  ? 46   LEU A CD1 1 
ATOM   362  C CD2 . LEU A 1 46  ? 140.455 136.096 164.674 1.00 78.72  ? 46   LEU A CD2 1 
ATOM   363  N N   . VAL A 1 47  ? 144.805 137.530 163.550 1.00 68.97  ? 47   VAL A N   1 
ATOM   364  C CA  . VAL A 1 47  ? 145.888 136.567 163.370 1.00 71.52  ? 47   VAL A CA  1 
ATOM   365  C C   . VAL A 1 47  ? 147.137 137.043 164.097 1.00 83.57  ? 47   VAL A C   1 
ATOM   366  O O   . VAL A 1 47  ? 147.735 136.312 164.897 1.00 94.29  ? 47   VAL A O   1 
ATOM   367  C CB  . VAL A 1 47  ? 146.166 136.347 161.874 1.00 73.86  ? 47   VAL A CB  1 
ATOM   368  C CG1 . VAL A 1 47  ? 147.559 135.766 161.671 1.00 81.64  ? 47   VAL A CG1 1 
ATOM   369  C CG2 . VAL A 1 47  ? 145.111 135.440 161.272 1.00 86.13  ? 47   VAL A CG2 1 
ATOM   370  N N   . PHE A 1 48  ? 147.538 138.289 163.842 1.00 77.43  ? 48   PHE A N   1 
ATOM   371  C CA  . PHE A 1 48  ? 148.772 138.789 164.437 1.00 74.37  ? 48   PHE A CA  1 
ATOM   372  C C   . PHE A 1 48  ? 148.671 138.813 165.957 1.00 79.77  ? 48   PHE A C   1 
ATOM   373  O O   . PHE A 1 48  ? 149.556 138.306 166.661 1.00 93.74  ? 48   PHE A O   1 
ATOM   374  C CB  . PHE A 1 48  ? 149.085 140.183 163.897 1.00 81.97  ? 48   PHE A CB  1 
ATOM   375  C CG  . PHE A 1 48  ? 150.402 140.730 164.363 1.00 77.40  ? 48   PHE A CG  1 
ATOM   376  C CD1 . PHE A 1 48  ? 150.497 141.426 165.554 1.00 85.14  ? 48   PHE A CD1 1 
ATOM   377  C CD2 . PHE A 1 48  ? 151.543 140.555 163.605 1.00 75.24  ? 48   PHE A CD2 1 
ATOM   378  C CE1 . PHE A 1 48  ? 151.706 141.930 165.980 1.00 80.95  ? 48   PHE A CE1 1 
ATOM   379  C CE2 . PHE A 1 48  ? 152.752 141.059 164.027 1.00 80.24  ? 48   PHE A CE2 1 
ATOM   380  C CZ  . PHE A 1 48  ? 152.834 141.746 165.216 1.00 80.57  ? 48   PHE A CZ  1 
ATOM   381  N N   . SER A 1 49  ? 147.590 139.394 166.482 1.00 69.00  ? 49   SER A N   1 
ATOM   382  C CA  . SER A 1 49  ? 147.455 139.518 167.927 1.00 72.02  ? 49   SER A CA  1 
ATOM   383  C C   . SER A 1 49  ? 147.421 138.152 168.593 1.00 76.08  ? 49   SER A C   1 
ATOM   384  O O   . SER A 1 49  ? 148.095 137.933 169.606 1.00 85.74  ? 49   SER A O   1 
ATOM   385  C CB  . SER A 1 49  ? 146.194 140.309 168.264 1.00 79.32  ? 49   SER A CB  1 
ATOM   386  O OG  . SER A 1 49  ? 146.147 141.521 167.533 1.00 87.77  ? 49   SER A OG  1 
ATOM   387  N N   . THR A 1 50  ? 146.644 137.218 168.043 1.00 74.19  ? 50   THR A N   1 
ATOM   388  C CA  . THR A 1 50  ? 146.534 135.905 168.658 1.00 70.46  ? 50   THR A CA  1 
ATOM   389  C C   . THR A 1 50  ? 147.862 135.170 168.628 1.00 76.19  ? 50   THR A C   1 
ATOM   390  O O   . THR A 1 50  ? 148.252 134.559 169.625 1.00 84.71  ? 50   THR A O   1 
ATOM   391  C CB  . THR A 1 50  ? 145.459 135.079 167.957 1.00 71.18  ? 50   THR A CB  1 
ATOM   392  O OG1 . THR A 1 50  ? 145.679 135.107 166.542 1.00 86.36  ? 50   THR A OG1 1 
ATOM   393  C CG2 . THR A 1 50  ? 144.080 135.629 168.269 1.00 84.20  ? 50   THR A CG2 1 
ATOM   394  N N   . ILE A 1 51  ? 148.578 135.210 167.502 1.00 68.00  ? 51   ILE A N   1 
ATOM   395  C CA  . ILE A 1 51  ? 149.856 134.507 167.438 1.00 66.60  ? 51   ILE A CA  1 
ATOM   396  C C   . ILE A 1 51  ? 150.821 135.081 168.465 1.00 73.13  ? 51   ILE A C   1 
ATOM   397  O O   . ILE A 1 51  ? 151.469 134.342 169.220 1.00 80.49  ? 51   ILE A O   1 
ATOM   398  C CB  . ILE A 1 51  ? 150.440 134.574 166.017 1.00 64.48  ? 51   ILE A CB  1 
ATOM   399  C CG1 . ILE A 1 51  ? 149.669 133.639 165.087 1.00 70.32  ? 51   ILE A CG1 1 
ATOM   400  C CG2 . ILE A 1 51  ? 151.917 134.207 166.036 1.00 66.16  ? 51   ILE A CG2 1 
ATOM   401  C CD1 . ILE A 1 51  ? 150.058 133.766 163.635 1.00 83.22  ? 51   ILE A CD1 1 
ATOM   402  N N   . VAL A 1 52  ? 150.927 136.411 168.517 1.00 79.87  ? 52   VAL A N   1 
ATOM   403  C CA  . VAL A 1 52  ? 151.884 137.031 169.428 1.00 72.87  ? 52   VAL A CA  1 
ATOM   404  C C   . VAL A 1 52  ? 151.525 136.707 170.872 1.00 82.90  ? 52   VAL A C   1 
ATOM   405  O O   . VAL A 1 52  ? 152.387 136.335 171.675 1.00 94.61  ? 52   VAL A O   1 
ATOM   406  C CB  . VAL A 1 52  ? 151.949 138.549 169.190 1.00 73.67  ? 52   VAL A CB  1 
ATOM   407  C CG1 . VAL A 1 52  ? 152.725 139.222 170.309 1.00 79.72  ? 52   VAL A CG1 1 
ATOM   408  C CG2 . VAL A 1 52  ? 152.582 138.842 167.842 1.00 85.90  ? 52   VAL A CG2 1 
ATOM   409  N N   . THR A 1 53  ? 150.244 136.839 171.225 1.00 86.39  ? 53   THR A N   1 
ATOM   410  C CA  . THR A 1 53  ? 149.830 136.565 172.596 1.00 84.51  ? 53   THR A CA  1 
ATOM   411  C C   . THR A 1 53  ? 150.054 135.104 172.958 1.00 85.14  ? 53   THR A C   1 
ATOM   412  O O   . THR A 1 53  ? 150.537 134.796 174.054 1.00 87.15  ? 53   THR A O   1 
ATOM   413  C CB  . THR A 1 53  ? 148.362 136.941 172.786 1.00 90.92  ? 53   THR A CB  1 
ATOM   414  O OG1 . THR A 1 53  ? 148.191 138.342 172.543 1.00 94.29  ? 53   THR A OG1 1 
ATOM   415  C CG2 . THR A 1 53  ? 147.906 136.616 174.197 1.00 95.03  ? 53   THR A CG2 1 
ATOM   416  N N   . GLY A 1 54  ? 149.713 134.187 172.053 1.00 81.98  ? 54   GLY A N   1 
ATOM   417  C CA  . GLY A 1 54  ? 149.879 132.777 172.350 1.00 88.65  ? 54   GLY A CA  1 
ATOM   418  C C   . GLY A 1 54  ? 151.330 132.402 172.566 1.00 88.40  ? 54   GLY A C   1 
ATOM   419  O O   . GLY A 1 54  ? 151.667 131.707 173.528 1.00 94.16  ? 54   GLY A O   1 
ATOM   420  N N   . ILE A 1 55  ? 152.215 132.861 171.679 1.00 70.15  ? 55   ILE A N   1 
ATOM   421  C CA  . ILE A 1 55  ? 153.630 132.546 171.852 1.00 68.55  ? 55   ILE A CA  1 
ATOM   422  C C   . ILE A 1 55  ? 154.162 133.189 173.125 1.00 76.40  ? 55   ILE A C   1 
ATOM   423  O O   . ILE A 1 55  ? 154.904 132.562 173.891 1.00 77.87  ? 55   ILE A O   1 
ATOM   424  C CB  . ILE A 1 55  ? 154.435 132.979 170.614 1.00 69.02  ? 55   ILE A CB  1 
ATOM   425  C CG1 . ILE A 1 55  ? 153.994 132.168 169.396 1.00 64.37  ? 55   ILE A CG1 1 
ATOM   426  C CG2 . ILE A 1 55  ? 155.925 132.788 170.861 1.00 76.14  ? 55   ILE A CG2 1 
ATOM   427  C CD1 . ILE A 1 55  ? 154.634 132.606 168.101 1.00 73.70  ? 55   ILE A CD1 1 
ATOM   428  N N   . ALA A 1 56  ? 153.794 134.448 173.376 1.00 89.08  ? 56   ALA A N   1 
ATOM   429  C CA  . ALA A 1 56  ? 154.276 135.129 174.571 1.00 87.28  ? 56   ALA A CA  1 
ATOM   430  C C   . ALA A 1 56  ? 153.764 134.470 175.844 1.00 89.65  ? 56   ALA A C   1 
ATOM   431  O O   . ALA A 1 56  ? 154.530 134.290 176.797 1.00 94.89  ? 56   ALA A O   1 
ATOM   432  C CB  . ALA A 1 56  ? 153.863 136.599 174.539 1.00 87.34  ? 56   ALA A CB  1 
ATOM   433  N N   . SER A 1 57  ? 152.482 134.105 175.884 1.00 95.04  ? 57   SER A N   1 
ATOM   434  C CA  . SER A 1 57  ? 151.929 133.494 177.086 1.00 98.68  ? 57   SER A CA  1 
ATOM   435  C C   . SER A 1 57  ? 152.573 132.149 177.385 1.00 98.97  ? 57   SER A C   1 
ATOM   436  O O   . SER A 1 57  ? 152.749 131.799 178.557 1.00 102.64 ? 57   SER A O   1 
ATOM   437  C CB  . SER A 1 57  ? 150.418 133.322 176.943 1.00 102.09 ? 57   SER A CB  1 
ATOM   438  O OG  . SER A 1 57  ? 150.095 131.996 176.564 1.00 103.18 ? 57   SER A OG  1 
ATOM   439  N N   . MET A 1 58  ? 152.929 131.387 176.350 1.00 96.63  ? 58   MET A N   1 
ATOM   440  C CA  . MET A 1 58  ? 153.574 130.099 176.573 1.00 93.65  ? 58   MET A CA  1 
ATOM   441  C C   . MET A 1 58  ? 154.893 130.258 177.314 1.00 99.15  ? 58   MET A C   1 
ATOM   442  O O   . MET A 1 58  ? 155.188 129.479 178.227 1.00 102.56 ? 58   MET A O   1 
ATOM   443  C CB  . MET A 1 58  ? 153.801 129.392 175.239 1.00 93.81  ? 58   MET A CB  1 
ATOM   444  C CG  . MET A 1 58  ? 154.091 127.907 175.371 1.00 99.31  ? 58   MET A CG  1 
ATOM   445  S SD  . MET A 1 58  ? 154.109 126.995 173.811 1.00 112.04 ? 58   MET A SD  1 
ATOM   446  C CE  . MET A 1 58  ? 154.120 128.306 172.591 1.00 99.19  ? 58   MET A CE  1 
ATOM   447  N N   . GLY A 1 59  ? 155.694 131.252 176.940 1.00 104.16 ? 59   GLY A N   1 
ATOM   448  C CA  . GLY A 1 59  ? 156.942 131.500 177.633 1.00 105.27 ? 59   GLY A CA  1 
ATOM   449  C C   . GLY A 1 59  ? 157.926 130.359 177.570 1.00 106.18 ? 59   GLY A C   1 
ATOM   450  O O   . GLY A 1 59  ? 158.661 130.131 178.534 1.00 99.70  ? 59   GLY A O   1 
ATOM   451  N N   . ASP A 1 60  ? 157.960 129.623 176.460 1.00 109.97 ? 60   ASP A N   1 
ATOM   452  C CA  . ASP A 1 60  ? 158.892 128.508 176.310 1.00 110.10 ? 60   ASP A CA  1 
ATOM   453  C C   . ASP A 1 60  ? 159.110 128.291 174.815 1.00 106.76 ? 60   ASP A C   1 
ATOM   454  O O   . ASP A 1 60  ? 158.292 127.643 174.156 1.00 106.69 ? 60   ASP A O   1 
ATOM   455  C CB  . ASP A 1 60  ? 158.357 127.255 176.988 1.00 111.85 ? 60   ASP A CB  1 
ATOM   456  C CG  . ASP A 1 60  ? 159.342 126.103 176.952 1.00 113.22 ? 60   ASP A CG  1 
ATOM   457  O OD1 . ASP A 1 60  ? 160.357 126.203 176.231 1.00 115.20 ? 60   ASP A OD1 1 
ATOM   458  O OD2 . ASP A 1 60  ? 159.100 125.095 177.647 1.00 109.77 ? 60   ASP A OD2 1 
ATOM   459  N N   . VAL A 1 61  ? 160.213 128.828 174.292 1.00 93.68  ? 61   VAL A N   1 
ATOM   460  C CA  . VAL A 1 61  ? 160.527 128.633 172.884 1.00 91.99  ? 61   VAL A CA  1 
ATOM   461  C C   . VAL A 1 61  ? 160.826 127.174 172.579 1.00 97.99  ? 61   VAL A C   1 
ATOM   462  O O   . VAL A 1 61  ? 160.484 126.689 171.495 1.00 106.08 ? 61   VAL A O   1 
ATOM   463  C CB  . VAL A 1 61  ? 161.710 129.523 172.465 1.00 95.95  ? 61   VAL A CB  1 
ATOM   464  C CG1 . VAL A 1 61  ? 162.032 129.317 170.993 1.00 94.27  ? 61   VAL A CG1 1 
ATOM   465  C CG2 . VAL A 1 61  ? 161.391 130.981 172.747 1.00 98.66  ? 61   VAL A CG2 1 
ATOM   466  N N   . LYS A 1 62  ? 161.459 126.453 173.506 1.00 104.69 ? 62   LYS A N   1 
ATOM   467  C CA  . LYS A 1 62  ? 161.720 125.038 173.273 1.00 101.52 ? 62   LYS A CA  1 
ATOM   468  C C   . LYS A 1 62  ? 160.420 124.271 173.085 1.00 102.69 ? 62   LYS A C   1 
ATOM   469  O O   . LYS A 1 62  ? 160.327 123.397 172.216 1.00 102.24 ? 62   LYS A O   1 
ATOM   470  C CB  . LYS A 1 62  ? 162.526 124.455 174.432 1.00 105.40 ? 62   LYS A CB  1 
ATOM   471  C CG  . LYS A 1 62  ? 163.873 125.126 174.646 1.00 109.19 ? 62   LYS A CG  1 
ATOM   472  C CD  . LYS A 1 62  ? 164.772 124.988 173.429 1.00 110.40 ? 62   LYS A CD  1 
ATOM   473  C CE  . LYS A 1 62  ? 166.181 125.472 173.724 1.00 110.45 ? 62   LYS A CE  1 
ATOM   474  N NZ  . LYS A 1 62  ? 167.060 125.391 172.526 1.00 112.69 ? 62   LYS A NZ  1 
ATOM   475  N N   . LYS A 1 63  ? 159.403 124.586 173.888 1.00 103.78 ? 63   LYS A N   1 
ATOM   476  C CA  . LYS A 1 63  ? 158.094 123.977 173.685 1.00 102.12 ? 63   LYS A CA  1 
ATOM   477  C C   . LYS A 1 63  ? 157.535 124.337 172.316 1.00 102.11 ? 63   LYS A C   1 
ATOM   478  O O   . LYS A 1 63  ? 156.915 123.500 171.651 1.00 110.08 ? 63   LYS A O   1 
ATOM   479  C CB  . LYS A 1 63  ? 157.134 124.418 174.787 1.00 106.14 ? 63   LYS A CB  1 
ATOM   480  C CG  . LYS A 1 63  ? 155.782 123.728 174.740 1.00 105.43 ? 63   LYS A CG  1 
ATOM   481  C CD  . LYS A 1 63  ? 154.975 124.005 175.998 1.00 107.59 ? 63   LYS A CD  1 
ATOM   482  C CE  . LYS A 1 63  ? 153.607 123.346 175.939 1.00 108.14 ? 63   LYS A CE  1 
ATOM   483  N NZ  . LYS A 1 63  ? 152.851 123.528 177.208 1.00 109.68 ? 63   LYS A NZ  1 
ATOM   484  N N   . LEU A 1 64  ? 157.747 125.579 171.878 1.00 86.31  ? 64   LEU A N   1 
ATOM   485  C CA  . LEU A 1 64  ? 157.239 126.001 170.578 1.00 86.64  ? 64   LEU A CA  1 
ATOM   486  C C   . LEU A 1 64  ? 157.810 125.138 169.462 1.00 89.90  ? 64   LEU A C   1 
ATOM   487  O O   . LEU A 1 64  ? 157.118 124.840 168.482 1.00 95.21  ? 64   LEU A O   1 
ATOM   488  C CB  . LEU A 1 64  ? 157.573 127.473 170.342 1.00 84.68  ? 64   LEU A CB  1 
ATOM   489  C CG  . LEU A 1 64  ? 157.249 128.044 168.961 1.00 80.42  ? 64   LEU A CG  1 
ATOM   490  C CD1 . LEU A 1 64  ? 155.752 128.199 168.794 1.00 85.89  ? 64   LEU A CD1 1 
ATOM   491  C CD2 . LEU A 1 64  ? 157.955 129.371 168.753 1.00 87.96  ? 64   LEU A CD2 1 
ATOM   492  N N   . GLY A 1 65  ? 159.074 124.734 169.585 1.00 92.37  ? 65   GLY A N   1 
ATOM   493  C CA  . GLY A 1 65  ? 159.689 123.946 168.530 1.00 89.98  ? 65   GLY A CA  1 
ATOM   494  C C   . GLY A 1 65  ? 158.974 122.632 168.295 1.00 94.71  ? 65   GLY A C   1 
ATOM   495  O O   . GLY A 1 65  ? 158.694 122.256 167.154 1.00 100.05 ? 65   GLY A O   1 
ATOM   496  N N   . ARG A 1 66  ? 158.669 121.912 169.375 1.00 101.28 ? 66   ARG A N   1 
ATOM   497  C CA  . ARG A 1 66  ? 157.984 120.632 169.238 1.00 100.12 ? 66   ARG A CA  1 
ATOM   498  C C   . ARG A 1 66  ? 156.627 120.816 168.575 1.00 104.27 ? 66   ARG A C   1 
ATOM   499  O O   . ARG A 1 66  ? 156.263 120.073 167.656 1.00 109.51 ? 66   ARG A O   1 
ATOM   500  C CB  . ARG A 1 66  ? 157.818 119.976 170.608 1.00 100.78 ? 66   ARG A CB  1 
ATOM   501  C CG  . ARG A 1 66  ? 159.119 119.608 171.293 1.00 105.41 ? 66   ARG A CG  1 
ATOM   502  C CD  . ARG A 1 66  ? 158.876 118.622 172.421 1.00 105.73 ? 66   ARG A CD  1 
ATOM   503  N NE  . ARG A 1 66  ? 157.930 119.145 173.400 1.00 106.39 ? 66   ARG A NE  1 
ATOM   504  C CZ  . ARG A 1 66  ? 158.262 119.870 174.460 1.00 103.54 ? 66   ARG A CZ  1 
ATOM   505  N NH1 . ARG A 1 66  ? 159.520 120.190 174.714 1.00 104.46 ? 66   ARG A NH1 1 
ATOM   506  N NH2 . ARG A 1 66  ? 157.306 120.288 175.284 1.00 98.57  ? 66   ARG A NH2 1 
ATOM   507  N N   . ILE A 1 67  ? 155.862 121.809 169.035 1.00 89.07  ? 67   ILE A N   1 
ATOM   508  C CA  . ILE A 1 67  ? 154.534 122.040 168.479 1.00 85.76  ? 67   ILE A CA  1 
ATOM   509  C C   . ILE A 1 67  ? 154.631 122.365 166.997 1.00 90.45  ? 67   ILE A C   1 
ATOM   510  O O   . ILE A 1 67  ? 153.896 121.806 166.175 1.00 94.76  ? 67   ILE A O   1 
ATOM   511  C CB  . ILE A 1 67  ? 153.819 123.160 169.256 1.00 87.46  ? 67   ILE A CB  1 
ATOM   512  C CG1 . ILE A 1 67  ? 153.388 122.658 170.634 1.00 87.62  ? 67   ILE A CG1 1 
ATOM   513  C CG2 . ILE A 1 67  ? 152.619 123.669 168.477 1.00 88.67  ? 67   ILE A CG2 1 
ATOM   514  C CD1 . ILE A 1 67  ? 153.162 123.763 171.637 1.00 93.47  ? 67   ILE A CD1 1 
ATOM   515  N N   . GLY A 1 68  ? 155.543 123.265 166.630 1.00 95.07  ? 68   GLY A N   1 
ATOM   516  C CA  . GLY A 1 68  ? 155.666 123.639 165.232 1.00 96.13  ? 68   GLY A CA  1 
ATOM   517  C C   . GLY A 1 68  ? 156.065 122.470 164.356 1.00 95.44  ? 68   GLY A C   1 
ATOM   518  O O   . GLY A 1 68  ? 155.481 122.245 163.292 1.00 100.54 ? 68   GLY A O   1 
ATOM   519  N N   . ALA A 1 69  ? 157.067 121.705 164.791 1.00 94.28  ? 69   ALA A N   1 
ATOM   520  C CA  . ALA A 1 69  ? 157.523 120.573 163.995 1.00 94.96  ? 69   ALA A CA  1 
ATOM   521  C C   . ALA A 1 69  ? 156.413 119.546 163.822 1.00 98.15  ? 69   ALA A C   1 
ATOM   522  O O   . ALA A 1 69  ? 156.138 119.091 162.703 1.00 100.90 ? 69   ALA A O   1 
ATOM   523  C CB  . ALA A 1 69  ? 158.751 119.937 164.646 1.00 97.05  ? 69   ALA A CB  1 
ATOM   524  N N   . LYS A 1 70  ? 155.755 119.170 164.922 1.00 93.32  ? 70   LYS A N   1 
ATOM   525  C CA  . LYS A 1 70  ? 154.689 118.182 164.831 1.00 91.07  ? 70   LYS A CA  1 
ATOM   526  C C   . LYS A 1 70  ? 153.561 118.678 163.939 1.00 93.13  ? 70   LYS A C   1 
ATOM   527  O O   . LYS A 1 70  ? 153.035 117.922 163.115 1.00 99.82  ? 70   LYS A O   1 
ATOM   528  C CB  . LYS A 1 70  ? 154.164 117.845 166.225 1.00 88.92  ? 70   LYS A CB  1 
ATOM   529  C CG  . LYS A 1 70  ? 154.972 116.777 166.941 1.00 92.80  ? 70   LYS A CG  1 
ATOM   530  C CD  . LYS A 1 70  ? 154.417 116.485 168.325 1.00 92.98  ? 70   LYS A CD  1 
ATOM   531  C CE  . LYS A 1 70  ? 154.761 117.590 169.308 1.00 94.93  ? 70   LYS A CE  1 
ATOM   532  N NZ  . LYS A 1 70  ? 154.501 117.188 170.716 1.00 91.71  ? 70   LYS A NZ  1 
ATOM   533  N N   . THR A 1 71  ? 153.181 119.949 164.080 1.00 87.65  ? 71   THR A N   1 
ATOM   534  C CA  . THR A 1 71  ? 152.094 120.487 163.273 1.00 95.38  ? 71   THR A CA  1 
ATOM   535  C C   . THR A 1 71  ? 152.450 120.470 161.793 1.00 99.40  ? 71   THR A C   1 
ATOM   536  O O   . THR A 1 71  ? 151.626 120.095 160.952 1.00 103.41 ? 71   THR A O   1 
ATOM   537  C CB  . THR A 1 71  ? 151.762 121.906 163.731 1.00 97.21  ? 71   THR A CB  1 
ATOM   538  O OG1 . THR A 1 71  ? 151.294 121.875 165.084 1.00 101.66 ? 71   THR A OG1 1 
ATOM   539  C CG2 . THR A 1 71  ? 150.696 122.515 162.845 1.00 92.22  ? 71   THR A CG2 1 
ATOM   540  N N   . LEU A 1 72  ? 153.673 120.877 161.449 1.00 94.19  ? 72   LEU A N   1 
ATOM   541  C CA  . LEU A 1 72  ? 154.066 120.891 160.043 1.00 93.72  ? 72   LEU A CA  1 
ATOM   542  C C   . LEU A 1 72  ? 154.082 119.482 159.465 1.00 100.20 ? 72   LEU A C   1 
ATOM   543  O O   . LEU A 1 72  ? 153.580 119.245 158.357 1.00 103.37 ? 72   LEU A O   1 
ATOM   544  C CB  . LEU A 1 72  ? 155.433 121.554 159.885 1.00 94.24  ? 72   LEU A CB  1 
ATOM   545  C CG  . LEU A 1 72  ? 155.459 123.067 160.102 1.00 100.50 ? 72   LEU A CG  1 
ATOM   546  C CD1 . LEU A 1 72  ? 156.889 123.566 160.193 1.00 100.89 ? 72   LEU A CD1 1 
ATOM   547  C CD2 . LEU A 1 72  ? 154.712 123.782 158.988 1.00 99.34  ? 72   LEU A CD2 1 
ATOM   548  N N   . ILE A 1 73  ? 154.655 118.528 160.202 1.00 98.31  ? 73   ILE A N   1 
ATOM   549  C CA  . ILE A 1 73  ? 154.708 117.160 159.698 1.00 98.59  ? 73   ILE A CA  1 
ATOM   550  C C   . ILE A 1 73  ? 153.302 116.609 159.520 1.00 98.15  ? 73   ILE A C   1 
ATOM   551  O O   . ILE A 1 73  ? 152.998 115.950 158.516 1.00 103.54 ? 73   ILE A O   1 
ATOM   552  C CB  . ILE A 1 73  ? 155.553 116.269 160.630 1.00 99.23  ? 73   ILE A CB  1 
ATOM   553  C CG1 . ILE A 1 73  ? 156.994 116.783 160.741 1.00 99.96  ? 73   ILE A CG1 1 
ATOM   554  C CG2 . ILE A 1 73  ? 155.564 114.836 160.127 1.00 102.29 ? 73   ILE A CG2 1 
ATOM   555  C CD1 . ILE A 1 73  ? 157.544 117.425 159.478 1.00 97.44  ? 73   ILE A CD1 1 
ATOM   556  N N   . TYR A 1 74  ? 152.421 116.864 160.488 1.00 88.75  ? 74   TYR A N   1 
ATOM   557  C CA  . TYR A 1 74  ? 151.055 116.371 160.377 1.00 85.75  ? 74   TYR A CA  1 
ATOM   558  C C   . TYR A 1 74  ? 150.344 117.001 159.187 1.00 90.15  ? 74   TYR A C   1 
ATOM   559  O O   . TYR A 1 74  ? 149.607 116.324 158.462 1.00 101.84 ? 74   TYR A O   1 
ATOM   560  C CB  . TYR A 1 74  ? 150.304 116.625 161.688 1.00 85.50  ? 74   TYR A CB  1 
ATOM   561  C CG  . TYR A 1 74  ? 148.796 116.595 161.576 1.00 88.91  ? 74   TYR A CG  1 
ATOM   562  C CD1 . TYR A 1 74  ? 148.102 117.639 160.981 1.00 92.08  ? 74   TYR A CD1 1 
ATOM   563  C CD2 . TYR A 1 74  ? 148.067 115.512 162.046 1.00 95.03  ? 74   TYR A CD2 1 
ATOM   564  C CE1 . TYR A 1 74  ? 146.736 117.613 160.868 1.00 94.69  ? 74   TYR A CE1 1 
ATOM   565  C CE2 . TYR A 1 74  ? 146.692 115.481 161.937 1.00 95.62  ? 74   TYR A CE2 1 
ATOM   566  C CZ  . TYR A 1 74  ? 146.033 116.536 161.347 1.00 95.94  ? 74   TYR A CZ  1 
ATOM   567  O OH  . TYR A 1 74  ? 144.663 116.525 161.227 1.00 104.20 ? 74   TYR A OH  1 
ATOM   568  N N   . TYR A 1 75  ? 150.537 118.304 158.977 1.00 91.89  ? 75   TYR A N   1 
ATOM   569  C CA  . TYR A 1 75  ? 149.909 118.950 157.831 1.00 97.36  ? 75   TYR A CA  1 
ATOM   570  C C   . TYR A 1 75  ? 150.372 118.311 156.532 1.00 105.62 ? 75   TYR A C   1 
ATOM   571  O O   . TYR A 1 75  ? 149.557 118.012 155.652 1.00 109.55 ? 75   TYR A O   1 
ATOM   572  C CB  . TYR A 1 75  ? 150.222 120.448 157.820 1.00 97.90  ? 75   TYR A CB  1 
ATOM   573  C CG  . TYR A 1 75  ? 149.466 121.276 158.839 1.00 99.99  ? 75   TYR A CG  1 
ATOM   574  C CD1 . TYR A 1 75  ? 148.287 120.818 159.412 1.00 98.29  ? 75   TYR A CD1 1 
ATOM   575  C CD2 . TYR A 1 75  ? 149.921 122.535 159.204 1.00 98.40  ? 75   TYR A CD2 1 
ATOM   576  C CE1 . TYR A 1 75  ? 147.599 121.581 160.330 1.00 100.37 ? 75   TYR A CE1 1 
ATOM   577  C CE2 . TYR A 1 75  ? 149.236 123.305 160.120 1.00 94.31  ? 75   TYR A CE2 1 
ATOM   578  C CZ  . TYR A 1 75  ? 148.077 122.822 160.681 1.00 97.19  ? 75   TYR A CZ  1 
ATOM   579  O OH  . TYR A 1 75  ? 147.390 123.585 161.596 1.00 100.95 ? 75   TYR A OH  1 
ATOM   580  N N   . MET A 1 76  ? 151.680 118.083 156.398 1.00 103.64 ? 76   MET A N   1 
ATOM   581  C CA  . MET A 1 76  ? 152.185 117.469 155.175 1.00 99.88  ? 76   MET A CA  1 
ATOM   582  C C   . MET A 1 76  ? 151.593 116.079 154.978 1.00 96.52  ? 76   MET A C   1 
ATOM   583  O O   . MET A 1 76  ? 151.160 115.730 153.870 1.00 98.42  ? 76   MET A O   1 
ATOM   584  C CB  . MET A 1 76  ? 153.712 117.397 155.219 1.00 97.86  ? 76   MET A CB  1 
ATOM   585  C CG  . MET A 1 76  ? 154.438 118.734 155.042 1.00 103.87 ? 76   MET A CG  1 
ATOM   586  S SD  . MET A 1 76  ? 153.508 120.035 154.205 1.00 119.28 ? 76   MET A SD  1 
ATOM   587  C CE  . MET A 1 76  ? 154.233 121.496 154.944 1.00 101.97 ? 76   MET A CE  1 
ATOM   588  N N   . ILE A 1 77  ? 151.557 115.276 156.044 1.00 87.80  ? 77   ILE A N   1 
ATOM   589  C CA  . ILE A 1 77  ? 151.056 113.910 155.927 1.00 84.83  ? 77   ILE A CA  1 
ATOM   590  C C   . ILE A 1 77  ? 149.588 113.915 155.521 1.00 90.50  ? 77   ILE A C   1 
ATOM   591  O O   . ILE A 1 77  ? 149.170 113.172 154.623 1.00 104.38 ? 77   ILE A O   1 
ATOM   592  C CB  . ILE A 1 77  ? 151.271 113.148 157.245 1.00 87.24  ? 77   ILE A CB  1 
ATOM   593  C CG1 . ILE A 1 77  ? 152.758 112.851 157.443 1.00 95.94  ? 77   ILE A CG1 1 
ATOM   594  C CG2 . ILE A 1 77  ? 150.464 111.860 157.248 1.00 85.75  ? 77   ILE A CG2 1 
ATOM   595  C CD1 . ILE A 1 77  ? 153.111 112.385 158.839 1.00 97.53  ? 77   ILE A CD1 1 
ATOM   596  N N   . THR A 1 78  ? 148.779 114.746 156.178 1.00 91.10  ? 78   THR A N   1 
ATOM   597  C CA  . THR A 1 78  ? 147.359 114.780 155.856 1.00 95.20  ? 78   THR A CA  1 
ATOM   598  C C   . THR A 1 78  ? 147.131 115.271 154.434 1.00 102.98 ? 78   THR A C   1 
ATOM   599  O O   . THR A 1 78  ? 146.251 114.765 153.733 1.00 109.67 ? 78   THR A O   1 
ATOM   600  C CB  . THR A 1 78  ? 146.602 115.654 156.853 1.00 97.68  ? 78   THR A CB  1 
ATOM   601  O OG1 . THR A 1 78  ? 147.154 116.976 156.854 1.00 109.67 ? 78   THR A OG1 1 
ATOM   602  C CG2 . THR A 1 78  ? 146.672 115.059 158.249 1.00 100.36 ? 78   THR A CG2 1 
ATOM   603  N N   . THR A 1 79  ? 147.912 116.256 153.984 1.00 105.77 ? 79   THR A N   1 
ATOM   604  C CA  . THR A 1 79  ? 147.742 116.740 152.619 1.00 108.15 ? 79   THR A CA  1 
ATOM   605  C C   . THR A 1 79  ? 148.077 115.664 151.593 1.00 113.15 ? 79   THR A C   1 
ATOM   606  O O   . THR A 1 79  ? 147.332 115.485 150.616 1.00 112.91 ? 79   THR A O   1 
ATOM   607  C CB  . THR A 1 79  ? 148.608 117.977 152.390 1.00 107.72 ? 79   THR A CB  1 
ATOM   608  O OG1 . THR A 1 79  ? 148.319 118.956 153.394 1.00 107.17 ? 79   THR A OG1 1 
ATOM   609  C CG2 . THR A 1 79  ? 148.337 118.574 151.019 1.00 109.31 ? 79   THR A CG2 1 
ATOM   610  N N   . THR A 1 80  ? 149.188 114.944 151.780 1.00 106.60 ? 80   THR A N   1 
ATOM   611  C CA  . THR A 1 80  ? 149.523 113.895 150.820 1.00 100.58 ? 80   THR A CA  1 
ATOM   612  C C   . THR A 1 80  ? 148.467 112.798 150.838 1.00 104.13 ? 80   THR A C   1 
ATOM   613  O O   . THR A 1 80  ? 148.087 112.268 149.789 1.00 109.79 ? 80   THR A O   1 
ATOM   614  C CB  . THR A 1 80  ? 150.908 113.303 151.092 1.00 101.22 ? 80   THR A CB  1 
ATOM   615  O OG1 . THR A 1 80  ? 151.097 112.155 150.259 1.00 104.12 ? 80   THR A OG1 1 
ATOM   616  C CG2 . THR A 1 80  ? 151.051 112.860 152.530 1.00 107.29 ? 80   THR A CG2 1 
ATOM   617  N N   . LEU A 1 81  ? 147.971 112.445 152.026 1.00 94.71  ? 81   LEU A N   1 
ATOM   618  C CA  . LEU A 1 81  ? 146.915 111.442 152.095 1.00 91.31  ? 81   LEU A CA  1 
ATOM   619  C C   . LEU A 1 81  ? 145.661 111.922 151.378 1.00 96.83  ? 81   LEU A C   1 
ATOM   620  O O   . LEU A 1 81  ? 144.987 111.142 150.696 1.00 107.42 ? 81   LEU A O   1 
ATOM   621  C CB  . LEU A 1 81  ? 146.604 111.104 153.553 1.00 88.75  ? 81   LEU A CB  1 
ATOM   622  C CG  . LEU A 1 81  ? 147.259 109.835 154.098 1.00 94.13  ? 81   LEU A CG  1 
ATOM   623  C CD1 . LEU A 1 81  ? 147.005 109.717 155.590 1.00 94.21  ? 81   LEU A CD1 1 
ATOM   624  C CD2 . LEU A 1 81  ? 146.755 108.592 153.369 1.00 98.37  ? 81   LEU A CD2 1 
ATOM   625  N N   . ALA A 1 82  ? 145.331 113.206 151.521 1.00 87.01  ? 82   ALA A N   1 
ATOM   626  C CA  . ALA A 1 82  ? 144.150 113.746 150.862 1.00 88.80  ? 82   ALA A CA  1 
ATOM   627  C C   . ALA A 1 82  ? 144.279 113.665 149.348 1.00 94.07  ? 82   ALA A C   1 
ATOM   628  O O   . ALA A 1 82  ? 143.341 113.252 148.657 1.00 99.26  ? 82   ALA A O   1 
ATOM   629  C CB  . ALA A 1 82  ? 143.924 115.191 151.300 1.00 91.04  ? 82   ALA A CB  1 
ATOM   630  N N   . VAL A 1 83  ? 145.435 114.056 148.810 1.00 97.12  ? 83   VAL A N   1 
ATOM   631  C CA  . VAL A 1 83  ? 145.600 114.005 147.358 1.00 97.80  ? 83   VAL A CA  1 
ATOM   632  C C   . VAL A 1 83  ? 145.605 112.559 146.876 1.00 97.78  ? 83   VAL A C   1 
ATOM   633  O O   . VAL A 1 83  ? 145.099 112.248 145.790 1.00 103.14 ? 83   VAL A O   1 
ATOM   634  C CB  . VAL A 1 83  ? 146.867 114.764 146.922 1.00 102.40 ? 83   VAL A CB  1 
ATOM   635  C CG1 . VAL A 1 83  ? 148.088 113.889 147.019 1.00 100.44 ? 83   VAL A CG1 1 
ATOM   636  C CG2 . VAL A 1 83  ? 146.704 115.274 145.505 1.00 102.63 ? 83   VAL A CG2 1 
ATOM   637  N N   . THR A 1 84  ? 146.170 111.649 147.674 1.00 100.20 ? 84   THR A N   1 
ATOM   638  C CA  . THR A 1 84  ? 146.137 110.234 147.316 1.00 99.64  ? 84   THR A CA  1 
ATOM   639  C C   . THR A 1 84  ? 144.704 109.724 147.245 1.00 101.01 ? 84   THR A C   1 
ATOM   640  O O   . THR A 1 84  ? 144.333 109.001 146.312 1.00 105.62 ? 84   THR A O   1 
ATOM   641  C CB  . THR A 1 84  ? 146.944 109.422 148.327 1.00 98.94  ? 84   THR A CB  1 
ATOM   642  O OG1 . THR A 1 84  ? 148.297 109.891 148.351 1.00 110.35 ? 84   THR A OG1 1 
ATOM   643  C CG2 . THR A 1 84  ? 146.928 107.947 147.966 1.00 102.15 ? 84   THR A CG2 1 
ATOM   644  N N   . ILE A 1 85  ? 143.883 110.089 148.231 1.00 89.95  ? 85   ILE A N   1 
ATOM   645  C CA  . ILE A 1 85  ? 142.481 109.683 148.214 1.00 87.42  ? 85   ILE A CA  1 
ATOM   646  C C   . ILE A 1 85  ? 141.780 110.266 147.000 1.00 90.62  ? 85   ILE A C   1 
ATOM   647  O O   . ILE A 1 85  ? 140.963 109.593 146.358 1.00 96.02  ? 85   ILE A O   1 
ATOM   648  C CB  . ILE A 1 85  ? 141.789 110.106 149.525 1.00 84.89  ? 85   ILE A CB  1 
ATOM   649  C CG1 . ILE A 1 85  ? 141.908 108.990 150.564 1.00 91.78  ? 85   ILE A CG1 1 
ATOM   650  C CG2 . ILE A 1 85  ? 140.322 110.448 149.280 1.00 88.52  ? 85   ILE A CG2 1 
ATOM   651  C CD1 . ILE A 1 85  ? 141.432 109.383 151.945 1.00 86.64  ? 85   ILE A CD1 1 
ATOM   652  N N   . GLY A 1 86  ? 142.066 111.527 146.677 1.00 99.78  ? 86   GLY A N   1 
ATOM   653  C CA  . GLY A 1 86  ? 141.459 112.127 145.501 1.00 102.85 ? 86   GLY A CA  1 
ATOM   654  C C   . GLY A 1 86  ? 141.795 111.364 144.235 1.00 96.33  ? 86   GLY A C   1 
ATOM   655  O O   . GLY A 1 86  ? 140.916 111.067 143.422 1.00 95.33  ? 86   GLY A O   1 
ATOM   656  N N   . LEU A 1 87  ? 143.075 111.027 144.057 1.00 102.26 ? 87   LEU A N   1 
ATOM   657  C CA  . LEU A 1 87  ? 143.473 110.258 142.882 1.00 101.44 ? 87   LEU A CA  1 
ATOM   658  C C   . LEU A 1 87  ? 142.782 108.902 142.852 1.00 103.34 ? 87   LEU A C   1 
ATOM   659  O O   . LEU A 1 87  ? 142.297 108.465 141.801 1.00 103.11 ? 87   LEU A O   1 
ATOM   660  C CB  . LEU A 1 87  ? 144.989 110.074 142.858 1.00 102.82 ? 87   LEU A CB  1 
ATOM   661  C CG  . LEU A 1 87  ? 145.828 111.321 142.589 1.00 106.15 ? 87   LEU A CG  1 
ATOM   662  C CD1 . LEU A 1 87  ? 147.306 111.001 142.715 1.00 103.88 ? 87   LEU A CD1 1 
ATOM   663  C CD2 . LEU A 1 87  ? 145.519 111.871 141.213 1.00 103.39 ? 87   LEU A CD2 1 
ATOM   664  N N   . ILE A 1 88  ? 142.735 108.217 143.995 1.00 104.24 ? 88   ILE A N   1 
ATOM   665  C CA  . ILE A 1 88  ? 142.129 106.889 144.039 1.00 103.52 ? 88   ILE A CA  1 
ATOM   666  C C   . ILE A 1 88  ? 140.668 106.969 143.618 1.00 108.43 ? 88   ILE A C   1 
ATOM   667  O O   . ILE A 1 88  ? 140.200 106.202 142.768 1.00 110.09 ? 88   ILE A O   1 
ATOM   668  C CB  . ILE A 1 88  ? 142.274 106.278 145.443 1.00 103.85 ? 88   ILE A CB  1 
ATOM   669  C CG1 . ILE A 1 88  ? 143.701 105.781 145.659 1.00 108.25 ? 88   ILE A CG1 1 
ATOM   670  C CG2 . ILE A 1 88  ? 141.289 105.137 145.634 1.00 102.57 ? 88   ILE A CG2 1 
ATOM   671  C CD1 . ILE A 1 88  ? 144.130 105.786 147.108 1.00 110.84 ? 88   ILE A CD1 1 
ATOM   672  N N   . LEU A 1 89  ? 139.925 107.907 144.208 1.00 106.27 ? 89   LEU A N   1 
ATOM   673  C CA  . LEU A 1 89  ? 138.505 108.013 143.897 1.00 101.89 ? 89   LEU A CA  1 
ATOM   674  C C   . LEU A 1 89  ? 138.285 108.419 142.447 1.00 104.80 ? 89   LEU A C   1 
ATOM   675  O O   . LEU A 1 89  ? 137.382 107.900 141.781 1.00 104.26 ? 89   LEU A O   1 
ATOM   676  C CB  . LEU A 1 89  ? 137.831 109.003 144.842 1.00 97.27  ? 89   LEU A CB  1 
ATOM   677  C CG  . LEU A 1 89  ? 137.457 108.412 146.199 1.00 102.83 ? 89   LEU A CG  1 
ATOM   678  C CD1 . LEU A 1 89  ? 137.038 109.508 147.144 1.00 105.07 ? 89   LEU A CD1 1 
ATOM   679  C CD2 . LEU A 1 89  ? 136.347 107.383 146.054 1.00 104.84 ? 89   LEU A CD2 1 
ATOM   680  N N   . ALA A 1 90  ? 139.098 109.344 141.934 1.00 112.80 ? 90   ALA A N   1 
ATOM   681  C CA  . ALA A 1 90  ? 138.954 109.734 140.539 1.00 111.28 ? 90   ALA A CA  1 
ATOM   682  C C   . ALA A 1 90  ? 139.182 108.550 139.614 1.00 110.11 ? 90   ALA A C   1 
ATOM   683  O O   . ALA A 1 90  ? 138.434 108.363 138.648 1.00 111.35 ? 90   ALA A O   1 
ATOM   684  C CB  . ALA A 1 90  ? 139.926 110.863 140.204 1.00 115.02 ? 90   ALA A CB  1 
ATOM   685  N N   . ASN A 1 91  ? 140.201 107.736 139.894 1.00 103.28 ? 91   ASN A N   1 
ATOM   686  C CA  . ASN A 1 91  ? 140.439 106.555 139.073 1.00 105.56 ? 91   ASN A CA  1 
ATOM   687  C C   . ASN A 1 91  ? 139.283 105.569 139.178 1.00 108.26 ? 91   ASN A C   1 
ATOM   688  O O   . ASN A 1 91  ? 138.874 104.975 138.173 1.00 109.14 ? 91   ASN A O   1 
ATOM   689  C CB  . ASN A 1 91  ? 141.749 105.889 139.484 1.00 104.81 ? 91   ASN A CB  1 
ATOM   690  C CG  . ASN A 1 91  ? 142.961 106.629 138.969 1.00 109.93 ? 91   ASN A CG  1 
ATOM   691  O OD1 . ASN A 1 91  ? 142.844 107.714 138.402 1.00 110.57 ? 91   ASN A OD1 1 
ATOM   692  N ND2 . ASN A 1 91  ? 144.137 106.045 139.162 1.00 112.98 ? 91   ASN A ND2 1 
ATOM   693  N N   . ILE A 1 92  ? 138.745 105.379 140.383 1.00 109.07 ? 92   ILE A N   1 
ATOM   694  C CA  . ILE A 1 92  ? 137.681 104.398 140.571 1.00 110.17 ? 92   ILE A CA  1 
ATOM   695  C C   . ILE A 1 92  ? 136.437 104.802 139.788 1.00 113.36 ? 92   ILE A C   1 
ATOM   696  O O   . ILE A 1 92  ? 135.833 103.982 139.087 1.00 110.21 ? 92   ILE A O   1 
ATOM   697  C CB  . ILE A 1 92  ? 137.377 104.224 142.070 1.00 108.69 ? 92   ILE A CB  1 
ATOM   698  C CG1 . ILE A 1 92  ? 138.441 103.324 142.710 1.00 109.78 ? 92   ILE A CG1 1 
ATOM   699  C CG2 . ILE A 1 92  ? 135.960 103.666 142.269 1.00 110.03 ? 92   ILE A CG2 1 
ATOM   700  C CD1 . ILE A 1 92  ? 138.082 102.782 144.080 1.00 111.52 ? 92   ILE A CD1 1 
ATOM   701  N N   . PHE A 1 93  ? 136.036 106.068 139.895 1.00 113.35 ? 93   PHE A N   1 
ATOM   702  C CA  . PHE A 1 93  ? 134.792 106.525 139.290 1.00 110.68 ? 93   PHE A CA  1 
ATOM   703  C C   . PHE A 1 93  ? 134.956 106.996 137.853 1.00 109.13 ? 93   PHE A C   1 
ATOM   704  O O   . PHE A 1 93  ? 133.985 106.953 137.090 1.00 110.57 ? 93   PHE A O   1 
ATOM   705  C CB  . PHE A 1 93  ? 134.188 107.660 140.120 1.00 112.37 ? 93   PHE A CB  1 
ATOM   706  C CG  . PHE A 1 93  ? 133.456 107.189 141.340 1.00 111.60 ? 93   PHE A CG  1 
ATOM   707  C CD1 . PHE A 1 93  ? 134.149 106.796 142.470 1.00 111.40 ? 93   PHE A CD1 1 
ATOM   708  C CD2 . PHE A 1 93  ? 132.074 107.137 141.355 1.00 108.84 ? 93   PHE A CD2 1 
ATOM   709  C CE1 . PHE A 1 93  ? 133.477 106.362 143.594 1.00 111.44 ? 93   PHE A CE1 1 
ATOM   710  C CE2 . PHE A 1 93  ? 131.397 106.703 142.476 1.00 110.39 ? 93   PHE A CE2 1 
ATOM   711  C CZ  . PHE A 1 93  ? 132.099 106.315 143.596 1.00 113.98 ? 93   PHE A CZ  1 
ATOM   712  N N   . LYS A 1 94  ? 136.146 107.440 137.466 1.00 117.05 ? 94   LYS A N   1 
ATOM   713  C CA  . LYS A 1 94  ? 136.409 107.910 136.112 1.00 119.89 ? 94   LYS A CA  1 
ATOM   714  C C   . LYS A 1 94  ? 135.419 109.010 135.719 1.00 120.48 ? 94   LYS A C   1 
ATOM   715  O O   . LYS A 1 94  ? 134.670 108.863 134.748 1.00 123.49 ? 94   LYS A O   1 
ATOM   716  C CB  . LYS A 1 94  ? 136.347 106.754 135.123 1.00 123.23 ? 94   LYS A CB  1 
ATOM   717  C CG  . LYS A 1 94  ? 137.123 105.526 135.562 1.00 124.12 ? 94   LYS A CG  1 
ATOM   718  C CD  . LYS A 1 94  ? 137.212 104.497 134.448 1.00 123.86 ? 94   LYS A CD  1 
ATOM   719  C CE  . LYS A 1 94  ? 137.737 103.167 134.961 1.00 123.75 ? 94   LYS A CE  1 
ATOM   720  N NZ  . LYS A 1 94  ? 139.089 103.293 135.571 1.00 121.89 ? 94   LYS A NZ  1 
ATOM   721  N N   . PRO A 1 95  ? 135.390 110.123 136.455 1.00 112.48 ? 95   PRO A N   1 
ATOM   722  C CA  . PRO A 1 95  ? 134.409 111.176 136.152 1.00 110.48 ? 95   PRO A CA  1 
ATOM   723  C C   . PRO A 1 95  ? 134.550 111.764 134.761 1.00 112.01 ? 95   PRO A C   1 
ATOM   724  O O   . PRO A 1 95  ? 133.548 112.219 134.198 1.00 110.87 ? 95   PRO A O   1 
ATOM   725  C CB  . PRO A 1 95  ? 134.684 112.230 137.231 1.00 106.67 ? 95   PRO A CB  1 
ATOM   726  C CG  . PRO A 1 95  ? 136.108 112.016 137.602 1.00 112.21 ? 95   PRO A CG  1 
ATOM   727  C CD  . PRO A 1 95  ? 136.324 110.533 137.516 1.00 113.90 ? 95   PRO A CD  1 
ATOM   728  N N   . GLY A 1 96  ? 135.750 111.777 134.190 1.00 113.68 ? 96   GLY A N   1 
ATOM   729  C CA  . GLY A 1 96  ? 135.981 112.376 132.896 1.00 112.36 ? 96   GLY A CA  1 
ATOM   730  C C   . GLY A 1 96  ? 135.686 111.497 131.704 1.00 113.37 ? 96   GLY A C   1 
ATOM   731  O O   . GLY A 1 96  ? 135.834 111.954 130.566 1.00 110.28 ? 96   GLY A O   1 
ATOM   732  N N   . LYS A 1 97  ? 135.277 110.250 131.917 1.00 124.47 ? 97   LYS A N   1 
ATOM   733  C CA  . LYS A 1 97  ? 134.912 109.391 130.802 1.00 125.35 ? 97   LYS A CA  1 
ATOM   734  C C   . LYS A 1 97  ? 133.576 109.828 130.212 1.00 129.35 ? 97   LYS A C   1 
ATOM   735  O O   . LYS A 1 97  ? 132.745 110.446 130.883 1.00 127.37 ? 97   LYS A O   1 
ATOM   736  C CB  . LYS A 1 97  ? 134.834 107.931 131.250 1.00 125.17 ? 97   LYS A CB  1 
ATOM   737  C CG  . LYS A 1 97  ? 134.609 106.951 130.108 1.00 129.57 ? 97   LYS A CG  1 
ATOM   738  C CD  . LYS A 1 97  ? 134.604 105.514 130.591 1.00 130.54 ? 97   LYS A CD  1 
ATOM   739  C CE  . LYS A 1 97  ? 134.196 104.563 129.478 1.00 131.33 ? 97   LYS A CE  1 
ATOM   740  N NZ  . LYS A 1 97  ? 134.182 103.144 129.927 1.00 133.77 ? 97   LYS A NZ  1 
ATOM   741  N N   . GLY A 1 98  ? 133.375 109.501 128.939 1.00 146.67 ? 98   GLY A N   1 
ATOM   742  C CA  . GLY A 1 98  ? 132.155 109.886 128.260 1.00 145.65 ? 98   GLY A CA  1 
ATOM   743  C C   . GLY A 1 98  ? 132.050 111.365 127.985 1.00 142.52 ? 98   GLY A C   1 
ATOM   744  O O   . GLY A 1 98  ? 130.938 111.894 127.888 1.00 142.92 ? 98   GLY A O   1 
ATOM   745  N N   . LEU A 1 99  ? 133.181 112.055 127.858 1.00 135.23 ? 99   LEU A N   1 
ATOM   746  C CA  . LEU A 1 99  ? 133.177 113.492 127.643 1.00 138.23 ? 99   LEU A CA  1 
ATOM   747  C C   . LEU A 1 99  ? 134.473 113.887 126.952 1.00 139.12 ? 99   LEU A C   1 
ATOM   748  O O   . LEU A 1 99  ? 135.546 113.392 127.304 1.00 137.42 ? 99   LEU A O   1 
ATOM   749  C CB  . LEU A 1 99  ? 133.027 114.247 128.968 1.00 136.37 ? 99   LEU A CB  1 
ATOM   750  C CG  . LEU A 1 99  ? 132.996 115.774 128.886 1.00 132.19 ? 99   LEU A CG  1 
ATOM   751  C CD1 . LEU A 1 99  ? 131.658 116.253 128.351 1.00 129.77 ? 99   LEU A CD1 1 
ATOM   752  C CD2 . LEU A 1 99  ? 133.279 116.379 130.248 1.00 130.39 ? 99   LEU A CD2 1 
ATOM   753  N N   . SER A 1 100 ? 134.360 114.773 125.966 1.00 143.83 ? 100  SER A N   1 
ATOM   754  C CA  . SER A 1 100 ? 135.529 115.310 125.274 1.00 142.95 ? 100  SER A CA  1 
ATOM   755  C C   . SER A 1 100 ? 135.105 116.595 124.586 1.00 143.42 ? 100  SER A C   1 
ATOM   756  O O   . SER A 1 100 ? 134.309 116.554 123.642 1.00 138.02 ? 100  SER A O   1 
ATOM   757  C CB  . SER A 1 100 ? 136.083 114.307 124.263 1.00 135.95 ? 100  SER A CB  1 
ATOM   758  O OG  . SER A 1 100 ? 137.362 114.705 123.802 1.00 128.20 ? 100  SER A OG  1 
ATOM   759  N N   . LEU A 1 101 ? 135.633 117.726 125.047 1.00 153.01 ? 101  LEU A N   1 
ATOM   760  C CA  . LEU A 1 101 ? 135.204 119.032 124.574 1.00 152.05 ? 101  LEU A CA  1 
ATOM   761  C C   . LEU A 1 101 ? 136.412 119.897 124.253 1.00 152.55 ? 101  LEU A C   1 
ATOM   762  O O   . LEU A 1 101 ? 137.392 119.919 125.003 1.00 150.17 ? 101  LEU A O   1 
ATOM   763  C CB  . LEU A 1 101 ? 134.328 119.733 125.619 1.00 150.24 ? 101  LEU A CB  1 
ATOM   764  C CG  . LEU A 1 101 ? 132.988 119.058 125.921 1.00 148.07 ? 101  LEU A CG  1 
ATOM   765  C CD1 . LEU A 1 101 ? 132.293 119.749 127.084 1.00 147.90 ? 101  LEU A CD1 1 
ATOM   766  C CD2 . LEU A 1 101 ? 132.096 119.048 124.689 1.00 146.89 ? 101  LEU A CD2 1 
ATOM   767  N N   . GLY A 1 102 ? 136.331 120.609 123.131 1.00 159.01 ? 102  GLY A N   1 
ATOM   768  C CA  . GLY A 1 102 ? 137.356 121.558 122.750 1.00 156.81 ? 102  GLY A CA  1 
ATOM   769  C C   . GLY A 1 102 ? 138.646 120.912 122.292 1.00 160.02 ? 102  GLY A C   1 
ATOM   770  O O   . GLY A 1 102 ? 138.969 119.788 122.689 1.00 159.33 ? 102  GLY A O   1 
ATOM   771  N N   . GLU A 1 103 ? 139.391 121.621 121.449 1.00 166.10 ? 103  GLU A N   1 
ATOM   772  C CA  . GLU A 1 103 ? 140.691 121.161 120.996 1.00 163.96 ? 103  GLU A CA  1 
ATOM   773  C C   . GLU A 1 103 ? 141.762 121.502 122.029 1.00 165.27 ? 103  GLU A C   1 
ATOM   774  O O   . GLU A 1 103 ? 141.519 122.206 123.013 1.00 164.63 ? 103  GLU A O   1 
ATOM   775  C CB  . GLU A 1 103 ? 141.049 121.796 119.652 1.00 160.00 ? 103  GLU A CB  1 
ATOM   776  C CG  . GLU A 1 103 ? 139.923 121.795 118.631 1.00 161.79 ? 103  GLU A CG  1 
ATOM   777  C CD  . GLU A 1 103 ? 139.464 120.397 118.273 1.00 164.89 ? 103  GLU A CD  1 
ATOM   778  O OE1 . GLU A 1 103 ? 140.301 119.471 118.294 1.00 164.01 ? 103  GLU A OE1 1 
ATOM   779  O OE2 . GLU A 1 103 ? 138.265 120.225 117.969 1.00 165.38 ? 103  GLU A OE2 1 
ATOM   780  N N   . ILE A 1 104 ? 142.968 120.990 121.794 1.00 155.02 ? 104  ILE A N   1 
ATOM   781  C CA  . ILE A 1 104 ? 144.137 121.432 122.544 1.00 155.12 ? 104  ILE A CA  1 
ATOM   782  C C   . ILE A 1 104 ? 144.670 122.652 121.807 1.00 154.57 ? 104  ILE A C   1 
ATOM   783  O O   . ILE A 1 104 ? 145.586 122.550 120.984 1.00 150.94 ? 104  ILE A O   1 
ATOM   784  C CB  . ILE A 1 104 ? 145.196 120.321 122.665 1.00 152.78 ? 104  ILE A CB  1 
ATOM   785  C CG1 . ILE A 1 104 ? 144.562 119.049 123.239 1.00 149.93 ? 104  ILE A CG1 1 
ATOM   786  C CG2 . ILE A 1 104 ? 146.349 120.782 123.545 1.00 148.55 ? 104  ILE A CG2 1 
ATOM   787  C CD1 . ILE A 1 104 ? 145.491 117.852 123.272 1.00 144.74 ? 104  ILE A CD1 1 
ATOM   788  N N   . HIS A 1 105 ? 144.091 123.815 122.106 1.00 167.67 ? 105  HIS A N   1 
ATOM   789  C CA  . HIS A 1 105 ? 144.235 124.969 121.224 1.00 166.40 ? 105  HIS A CA  1 
ATOM   790  C C   . HIS A 1 105 ? 145.659 125.512 121.235 1.00 165.70 ? 105  HIS A C   1 
ATOM   791  O O   . HIS A 1 105 ? 146.252 125.747 120.176 1.00 166.71 ? 105  HIS A O   1 
ATOM   792  C CB  . HIS A 1 105 ? 143.240 126.054 121.632 1.00 163.89 ? 105  HIS A CB  1 
ATOM   793  C CG  . HIS A 1 105 ? 141.821 125.728 121.283 1.00 165.37 ? 105  HIS A CG  1 
ATOM   794  N ND1 . HIS A 1 105 ? 141.311 125.888 120.013 1.00 165.97 ? 105  HIS A ND1 1 
ATOM   795  C CD2 . HIS A 1 105 ? 140.806 125.244 122.037 1.00 164.72 ? 105  HIS A CD2 1 
ATOM   796  C CE1 . HIS A 1 105 ? 140.042 125.520 120.000 1.00 163.88 ? 105  HIS A CE1 1 
ATOM   797  N NE2 . HIS A 1 105 ? 139.711 125.125 121.216 1.00 164.32 ? 105  HIS A NE2 1 
ATOM   798  N N   . GLU A 1 106 ? 146.228 125.717 122.420 1.00 174.46 ? 106  GLU A N   1 
ATOM   799  C CA  . GLU A 1 106 ? 147.511 126.396 122.519 1.00 174.63 ? 106  GLU A CA  1 
ATOM   800  C C   . GLU A 1 106 ? 148.263 125.905 123.746 1.00 177.71 ? 106  GLU A C   1 
ATOM   801  O O   . GLU A 1 106 ? 147.680 125.350 124.681 1.00 178.70 ? 106  GLU A O   1 
ATOM   802  C CB  . GLU A 1 106 ? 147.329 127.917 122.582 1.00 175.16 ? 106  GLU A CB  1 
ATOM   803  C CG  . GLU A 1 106 ? 148.610 128.703 122.368 1.00 175.16 ? 106  GLU A CG  1 
ATOM   804  C CD  . GLU A 1 106 ? 148.349 130.142 121.974 1.00 178.17 ? 106  GLU A CD  1 
ATOM   805  O OE1 . GLU A 1 106 ? 147.655 130.850 122.733 1.00 179.86 ? 106  GLU A OE1 1 
ATOM   806  O OE2 . GLU A 1 106 ? 148.835 130.564 120.904 1.00 177.73 ? 106  GLU A OE2 1 
ATOM   807  N N   . VAL A 1 107 ? 149.580 126.124 123.725 1.00 179.42 ? 107  VAL A N   1 
ATOM   808  C CA  . VAL A 1 107 ? 150.424 125.723 124.842 1.00 179.98 ? 107  VAL A CA  1 
ATOM   809  C C   . VAL A 1 107 ? 150.016 126.489 126.092 1.00 178.69 ? 107  VAL A C   1 
ATOM   810  O O   . VAL A 1 107 ? 149.465 127.596 126.020 1.00 173.62 ? 107  VAL A O   1 
ATOM   811  C CB  . VAL A 1 107 ? 151.906 125.960 124.502 1.00 175.22 ? 107  VAL A CB  1 
ATOM   812  C CG1 . VAL A 1 107 ? 152.175 127.444 124.251 1.00 172.54 ? 107  VAL A CG1 1 
ATOM   813  C CG2 . VAL A 1 107 ? 152.808 125.410 125.601 1.00 175.61 ? 107  VAL A CG2 1 
ATOM   814  N N   . ALA A 1 108 ? 150.285 125.896 127.252 1.00 177.44 ? 108  ALA A N   1 
ATOM   815  C CA  . ALA A 1 108 ? 149.913 126.505 128.519 1.00 175.84 ? 108  ALA A CA  1 
ATOM   816  C C   . ALA A 1 108 ? 150.882 127.626 128.885 1.00 176.62 ? 108  ALA A C   1 
ATOM   817  O O   . ALA A 1 108 ? 151.814 127.949 128.143 1.00 177.48 ? 108  ALA A O   1 
ATOM   818  C CB  . ALA A 1 108 ? 149.886 125.454 129.628 1.00 173.27 ? 108  ALA A CB  1 
ATOM   819  N N   . HIS A 1 109 ? 150.646 128.223 130.048 1.00 181.28 ? 109  HIS A N   1 
ATOM   820  C CA  . HIS A 1 109 ? 151.456 129.342 130.511 1.00 182.30 ? 109  HIS A CA  1 
ATOM   821  C C   . HIS A 1 109 ? 152.713 128.835 131.215 1.00 182.12 ? 109  HIS A C   1 
ATOM   822  O O   . HIS A 1 109 ? 152.602 128.163 132.251 1.00 179.31 ? 109  HIS A O   1 
ATOM   823  C CB  . HIS A 1 109 ? 150.642 130.220 131.458 1.00 181.37 ? 109  HIS A CB  1 
ATOM   824  C CG  . HIS A 1 109 ? 151.409 131.377 132.018 1.00 181.95 ? 109  HIS A CG  1 
ATOM   825  N ND1 . HIS A 1 109 ? 151.026 132.038 133.166 1.00 180.60 ? 109  HIS A ND1 1 
ATOM   826  C CD2 . HIS A 1 109 ? 152.532 131.998 131.585 1.00 181.32 ? 109  HIS A CD2 1 
ATOM   827  C CE1 . HIS A 1 109 ? 151.883 133.011 133.418 1.00 180.37 ? 109  HIS A CE1 1 
ATOM   828  N NE2 . HIS A 1 109 ? 152.806 133.008 132.474 1.00 180.85 ? 109  HIS A NE2 1 
ATOM   829  N N   . PRO A 1 110 ? 153.917 129.126 130.700 1.00 185.61 ? 110  PRO A N   1 
ATOM   830  C CA  . PRO A 1 110 ? 155.140 128.709 131.402 1.00 183.66 ? 110  PRO A CA  1 
ATOM   831  C C   . PRO A 1 110 ? 155.552 129.670 132.506 1.00 186.54 ? 110  PRO A C   1 
ATOM   832  O O   . PRO A 1 110 ? 154.777 130.543 132.910 1.00 188.48 ? 110  PRO A O   1 
ATOM   833  C CB  . PRO A 1 110 ? 156.194 128.670 130.283 1.00 180.99 ? 110  PRO A CB  1 
ATOM   834  C CG  . PRO A 1 110 ? 155.424 128.806 128.995 1.00 180.88 ? 110  PRO A CG  1 
ATOM   835  C CD  . PRO A 1 110 ? 154.236 129.624 129.354 1.00 184.21 ? 110  PRO A CD  1 
ATOM   836  N N   . ASN A 1 111 ? 156.761 129.465 133.033 1.00 192.25 ? 111  ASN A N   1 
ATOM   837  C CA  . ASN A 1 111 ? 157.476 130.407 133.899 1.00 192.23 ? 111  ASN A CA  1 
ATOM   838  C C   . ASN A 1 111 ? 156.767 130.665 135.225 1.00 190.99 ? 111  ASN A C   1 
ATOM   839  O O   . ASN A 1 111 ? 156.740 131.801 135.708 1.00 189.57 ? 111  ASN A O   1 
ATOM   840  C CB  . ASN A 1 111 ? 157.757 131.736 133.175 1.00 192.28 ? 111  ASN A CB  1 
ATOM   841  C CG  . ASN A 1 111 ? 156.504 132.558 132.912 1.00 191.64 ? 111  ASN A CG  1 
ATOM   842  O OD1 . ASN A 1 111 ? 155.882 133.086 133.833 1.00 189.93 ? 111  ASN A OD1 1 
ATOM   843  N ND2 . ASN A 1 111 ? 156.128 132.665 131.643 1.00 192.82 ? 111  ASN A ND2 1 
ATOM   844  N N   . ALA A 1 112 ? 156.215 129.629 135.850 1.00 176.79 ? 112  ALA A N   1 
ATOM   845  C CA  . ALA A 1 112 ? 155.760 129.770 137.222 1.00 175.22 ? 112  ALA A CA  1 
ATOM   846  C C   . ALA A 1 112 ? 156.971 129.887 138.149 1.00 175.77 ? 112  ALA A C   1 
ATOM   847  O O   . ALA A 1 112 ? 158.038 129.337 137.859 1.00 177.32 ? 112  ALA A O   1 
ATOM   848  C CB  . ALA A 1 112 ? 154.897 128.579 137.630 1.00 172.56 ? 112  ALA A CB  1 
ATOM   849  N N   . PRO A 1 113 ? 156.841 130.598 139.269 1.00 158.14 ? 113  PRO A N   1 
ATOM   850  C CA  . PRO A 1 113 ? 157.993 130.772 140.160 1.00 155.63 ? 113  PRO A CA  1 
ATOM   851  C C   . PRO A 1 113 ? 158.473 129.441 140.719 1.00 155.26 ? 113  PRO A C   1 
ATOM   852  O O   . PRO A 1 113 ? 157.698 128.509 140.943 1.00 155.70 ? 113  PRO A O   1 
ATOM   853  C CB  . PRO A 1 113 ? 157.455 131.686 141.267 1.00 153.95 ? 113  PRO A CB  1 
ATOM   854  C CG  . PRO A 1 113 ? 155.986 131.465 141.258 1.00 154.17 ? 113  PRO A CG  1 
ATOM   855  C CD  . PRO A 1 113 ? 155.621 131.208 139.825 1.00 156.91 ? 113  PRO A CD  1 
ATOM   856  N N   . SER A 1 114 ? 159.781 129.364 140.944 1.00 134.90 ? 114  SER A N   1 
ATOM   857  C CA  . SER A 1 114 ? 160.383 128.132 141.424 1.00 133.45 ? 114  SER A CA  1 
ATOM   858  C C   . SER A 1 114 ? 160.065 127.916 142.900 1.00 131.73 ? 114  SER A C   1 
ATOM   859  O O   . SER A 1 114 ? 159.593 128.813 143.604 1.00 129.78 ? 114  SER A O   1 
ATOM   860  C CB  . SER A 1 114 ? 161.897 128.159 141.221 1.00 131.72 ? 114  SER A CB  1 
ATOM   861  O OG  . SER A 1 114 ? 162.539 128.826 142.293 1.00 134.26 ? 114  SER A OG  1 
ATOM   862  N N   . PHE A 1 115 ? 160.336 126.696 143.366 1.00 126.26 ? 115  PHE A N   1 
ATOM   863  C CA  . PHE A 1 115 ? 160.103 126.370 144.767 1.00 124.49 ? 115  PHE A CA  1 
ATOM   864  C C   . PHE A 1 115 ? 160.891 127.287 145.690 1.00 125.40 ? 115  PHE A C   1 
ATOM   865  O O   . PHE A 1 115 ? 160.378 127.710 146.732 1.00 125.73 ? 115  PHE A O   1 
ATOM   866  C CB  . PHE A 1 115 ? 160.475 124.910 145.024 1.00 128.34 ? 115  PHE A CB  1 
ATOM   867  C CG  . PHE A 1 115 ? 160.166 124.437 146.415 1.00 127.01 ? 115  PHE A CG  1 
ATOM   868  C CD1 . PHE A 1 115 ? 158.864 124.431 146.887 1.00 124.62 ? 115  PHE A CD1 1 
ATOM   869  C CD2 . PHE A 1 115 ? 161.177 123.988 147.247 1.00 126.25 ? 115  PHE A CD2 1 
ATOM   870  C CE1 . PHE A 1 115 ? 158.578 123.991 148.165 1.00 122.75 ? 115  PHE A CE1 1 
ATOM   871  C CE2 . PHE A 1 115 ? 160.896 123.547 148.525 1.00 126.03 ? 115  PHE A CE2 1 
ATOM   872  C CZ  . PHE A 1 115 ? 159.595 123.547 148.984 1.00 125.67 ? 115  PHE A CZ  1 
ATOM   873  N N   . THR A 1 116 ? 162.134 127.608 145.328 1.00 124.16 ? 116  THR A N   1 
ATOM   874  C CA  . THR A 1 116 ? 162.957 128.455 146.185 1.00 121.35 ? 116  THR A CA  1 
ATOM   875  C C   . THR A 1 116 ? 162.358 129.849 146.330 1.00 124.29 ? 116  THR A C   1 
ATOM   876  O O   . THR A 1 116 ? 162.325 130.403 147.435 1.00 127.81 ? 116  THR A O   1 
ATOM   877  C CB  . THR A 1 116 ? 164.377 128.543 145.624 1.00 120.31 ? 116  THR A CB  1 
ATOM   878  O OG1 . THR A 1 116 ? 164.911 127.224 145.460 1.00 121.35 ? 116  THR A OG1 1 
ATOM   879  C CG2 . THR A 1 116 ? 165.277 129.334 146.560 1.00 120.35 ? 116  THR A CG2 1 
ATOM   880  N N   . GLU A 1 117 ? 161.874 130.430 145.231 1.00 126.49 ? 117  GLU A N   1 
ATOM   881  C CA  . GLU A 1 117 ? 161.365 131.796 145.288 1.00 121.84 ? 117  GLU A CA  1 
ATOM   882  C C   . GLU A 1 117 ? 160.183 131.906 146.241 1.00 122.98 ? 117  GLU A C   1 
ATOM   883  O O   . GLU A 1 117 ? 160.094 132.860 147.023 1.00 127.05 ? 117  GLU A O   1 
ATOM   884  C CB  . GLU A 1 117 ? 160.970 132.268 143.890 1.00 124.17 ? 117  GLU A CB  1 
ATOM   885  C CG  . GLU A 1 117 ? 162.106 132.919 143.118 1.00 129.12 ? 117  GLU A CG  1 
ATOM   886  C CD  . GLU A 1 117 ? 163.011 131.904 142.450 1.00 133.25 ? 117  GLU A CD  1 
ATOM   887  O OE1 . GLU A 1 117 ? 162.496 131.045 141.703 1.00 137.21 ? 117  GLU A OE1 1 
ATOM   888  O OE2 . GLU A 1 117 ? 164.238 131.962 142.673 1.00 129.82 ? 117  GLU A OE2 1 
ATOM   889  N N   . THR A 1 118 ? 159.264 130.940 146.195 1.00 117.26 ? 118  THR A N   1 
ATOM   890  C CA  . THR A 1 118 ? 158.122 130.982 147.099 1.00 118.40 ? 118  THR A CA  1 
ATOM   891  C C   . THR A 1 118 ? 158.564 130.935 148.554 1.00 118.01 ? 118  THR A C   1 
ATOM   892  O O   . THR A 1 118 ? 158.014 131.658 149.392 1.00 120.68 ? 118  THR A O   1 
ATOM   893  C CB  . THR A 1 118 ? 157.169 129.825 146.802 1.00 118.34 ? 118  THR A CB  1 
ATOM   894  O OG1 . THR A 1 118 ? 157.860 128.581 146.965 1.00 124.86 ? 118  THR A OG1 1 
ATOM   895  C CG2 . THR A 1 118 ? 156.633 129.926 145.384 1.00 115.73 ? 118  THR A CG2 1 
ATOM   896  N N   . LEU A 1 119 ? 159.552 130.099 148.874 1.00 116.28 ? 119  LEU A N   1 
ATOM   897  C CA  . LEU A 1 119 ? 160.054 130.040 150.242 1.00 117.55 ? 119  LEU A CA  1 
ATOM   898  C C   . LEU A 1 119 ? 160.675 131.369 150.653 1.00 118.67 ? 119  LEU A C   1 
ATOM   899  O O   . LEU A 1 119 ? 160.506 131.818 151.792 1.00 123.06 ? 119  LEU A O   1 
ATOM   900  C CB  . LEU A 1 119 ? 161.063 128.901 150.379 1.00 119.79 ? 119  LEU A CB  1 
ATOM   901  C CG  . LEU A 1 119 ? 160.451 127.562 150.793 1.00 122.54 ? 119  LEU A CG  1 
ATOM   902  C CD1 . LEU A 1 119 ? 159.933 126.816 149.579 1.00 123.08 ? 119  LEU A CD1 1 
ATOM   903  C CD2 . LEU A 1 119 ? 161.462 126.716 151.550 1.00 123.43 ? 119  LEU A CD2 1 
ATOM   904  N N   . LEU A 1 120 ? 161.407 132.011 149.742 1.00 108.92 ? 120  LEU A N   1 
ATOM   905  C CA  . LEU A 1 120 ? 162.006 133.302 150.065 1.00 106.15 ? 120  LEU A CA  1 
ATOM   906  C C   . LEU A 1 120 ? 160.939 134.370 150.260 1.00 107.53 ? 120  LEU A C   1 
ATOM   907  O O   . LEU A 1 120 ? 161.136 135.325 151.019 1.00 106.73 ? 120  LEU A O   1 
ATOM   908  C CB  . LEU A 1 120 ? 162.981 133.720 148.966 1.00 105.26 ? 120  LEU A CB  1 
ATOM   909  C CG  . LEU A 1 120 ? 164.329 133.000 148.960 1.00 110.68 ? 120  LEU A CG  1 
ATOM   910  C CD1 . LEU A 1 120 ? 165.092 133.322 147.687 1.00 112.21 ? 120  LEU A CD1 1 
ATOM   911  C CD2 . LEU A 1 120 ? 165.147 133.367 150.187 1.00 112.15 ? 120  LEU A CD2 1 
ATOM   912  N N   . ASN A 1 121 ? 159.803 134.232 149.578 1.00 105.09 ? 121  ASN A N   1 
ATOM   913  C CA  . ASN A 1 121 ? 158.738 135.221 149.680 1.00 102.08 ? 121  ASN A CA  1 
ATOM   914  C C   . ASN A 1 121 ? 157.975 135.143 150.992 1.00 101.65 ? 121  ASN A C   1 
ATOM   915  O O   . ASN A 1 121 ? 157.171 136.039 151.267 1.00 102.57 ? 121  ASN A O   1 
ATOM   916  C CB  . ASN A 1 121 ? 157.766 135.062 148.511 1.00 106.82 ? 121  ASN A CB  1 
ATOM   917  C CG  . ASN A 1 121 ? 158.193 135.849 147.290 1.00 108.17 ? 121  ASN A CG  1 
ATOM   918  O OD1 . ASN A 1 121 ? 157.830 137.014 147.130 1.00 106.49 ? 121  ASN A OD1 1 
ATOM   919  N ND2 . ASN A 1 121 ? 158.972 135.217 146.421 1.00 111.17 ? 121  ASN A ND2 1 
ATOM   920  N N   . MET A 1 122 ? 158.189 134.107 151.804 1.00 102.03 ? 122  MET A N   1 
ATOM   921  C CA  . MET A 1 122 ? 157.483 134.003 153.074 1.00 102.04 ? 122  MET A CA  1 
ATOM   922  C C   . MET A 1 122 ? 158.036 134.945 154.135 1.00 103.89 ? 122  MET A C   1 
ATOM   923  O O   . MET A 1 122 ? 157.345 135.208 155.124 1.00 102.63 ? 122  MET A O   1 
ATOM   924  C CB  . MET A 1 122 ? 157.527 132.566 153.595 1.00 99.03  ? 122  MET A CB  1 
ATOM   925  C CG  . MET A 1 122 ? 157.413 131.506 152.513 1.00 102.08 ? 122  MET A CG  1 
ATOM   926  S SD  . MET A 1 122 ? 156.597 130.006 153.086 1.00 104.45 ? 122  MET A SD  1 
ATOM   927  C CE  . MET A 1 122 ? 157.409 129.756 154.662 1.00 99.35  ? 122  MET A CE  1 
ATOM   928  N N   . ILE A 1 123 ? 159.251 135.450 153.966 1.00 98.61  ? 123  ILE A N   1 
ATOM   929  C CA  . ILE A 1 123 ? 159.817 136.456 154.860 1.00 91.80  ? 123  ILE A CA  1 
ATOM   930  C C   . ILE A 1 123 ? 159.531 137.825 154.251 1.00 99.75  ? 123  ILE A C   1 
ATOM   931  O O   . ILE A 1 123 ? 159.879 138.052 153.082 1.00 106.23 ? 123  ILE A O   1 
ATOM   932  C CB  . ILE A 1 123 ? 161.324 136.236 155.088 1.00 92.35  ? 123  ILE A CB  1 
ATOM   933  C CG1 . ILE A 1 123 ? 162.174 136.719 153.906 1.00 102.89 ? 123  ILE A CG1 1 
ATOM   934  C CG2 . ILE A 1 123 ? 161.603 134.765 155.344 1.00 87.98  ? 123  ILE A CG2 1 
ATOM   935  C CD1 . ILE A 1 123 ? 163.663 136.656 154.167 1.00 98.99  ? 123  ILE A CD1 1 
ATOM   936  N N   . PRO A 1 124 ? 158.869 138.734 154.964 1.00 84.08  ? 124  PRO A N   1 
ATOM   937  C CA  . PRO A 1 124 ? 158.584 140.047 154.376 1.00 82.64  ? 124  PRO A CA  1 
ATOM   938  C C   . PRO A 1 124 ? 159.785 140.972 154.463 1.00 85.30  ? 124  PRO A C   1 
ATOM   939  O O   . PRO A 1 124 ? 160.548 140.944 155.431 1.00 92.22  ? 124  PRO A O   1 
ATOM   940  C CB  . PRO A 1 124 ? 157.418 140.568 155.219 1.00 83.39  ? 124  PRO A CB  1 
ATOM   941  C CG  . PRO A 1 124 ? 157.595 139.913 156.536 1.00 84.96  ? 124  PRO A CG  1 
ATOM   942  C CD  . PRO A 1 124 ? 158.228 138.573 156.280 1.00 82.13  ? 124  PRO A CD  1 
ATOM   943  N N   . THR A 1 125 ? 159.948 141.799 153.431 1.00 91.49  ? 125  THR A N   1 
ATOM   944  C CA  . THR A 1 125 ? 160.965 142.841 153.461 1.00 99.48  ? 125  THR A CA  1 
ATOM   945  C C   . THR A 1 125 ? 160.508 144.067 154.236 1.00 105.45 ? 125  THR A C   1 
ATOM   946  O O   . THR A 1 125 ? 161.341 144.913 154.579 1.00 107.06 ? 125  THR A O   1 
ATOM   947  C CB  . THR A 1 125 ? 161.343 143.253 152.038 1.00 101.73 ? 125  THR A CB  1 
ATOM   948  O OG1 . THR A 1 125 ? 160.184 143.749 151.358 1.00 108.16 ? 125  THR A OG1 1 
ATOM   949  C CG2 . THR A 1 125 ? 161.909 142.070 151.271 1.00 100.86 ? 125  THR A CG2 1 
ATOM   950  N N   . ASN A 1 126 ? 159.212 144.182 154.515 1.00 103.88 ? 126  ASN A N   1 
ATOM   951  C CA  . ASN A 1 126 ? 158.668 145.296 155.279 1.00 97.30  ? 126  ASN A CA  1 
ATOM   952  C C   . ASN A 1 126 ? 157.400 144.805 155.969 1.00 90.16  ? 126  ASN A C   1 
ATOM   953  O O   . ASN A 1 126 ? 156.386 144.575 155.297 1.00 97.76  ? 126  ASN A O   1 
ATOM   954  C CB  . ASN A 1 126 ? 158.395 146.489 154.358 1.00 94.26  ? 126  ASN A CB  1 
ATOM   955  C CG  . ASN A 1 126 ? 157.477 147.535 154.979 1.00 102.36 ? 126  ASN A CG  1 
ATOM   956  O OD1 . ASN A 1 126 ? 156.566 147.226 155.746 1.00 110.04 ? 126  ASN A OD1 1 
ATOM   957  N ND2 . ASN A 1 126 ? 157.724 148.793 154.639 1.00 104.87 ? 126  ASN A ND2 1 
ATOM   958  N N   . PRO A 1 127 ? 157.403 144.635 157.294 1.00 73.46  ? 127  PRO A N   1 
ATOM   959  C CA  . PRO A 1 127 ? 156.216 144.060 157.950 1.00 78.99  ? 127  PRO A CA  1 
ATOM   960  C C   . PRO A 1 127 ? 154.936 144.819 157.660 1.00 91.46  ? 127  PRO A C   1 
ATOM   961  O O   . PRO A 1 127 ? 153.882 144.198 157.466 1.00 95.65  ? 127  PRO A O   1 
ATOM   962  C CB  . PRO A 1 127 ? 156.579 144.118 159.440 1.00 81.22  ? 127  PRO A CB  1 
ATOM   963  C CG  . PRO A 1 127 ? 158.058 144.182 159.477 1.00 80.91  ? 127  PRO A CG  1 
ATOM   964  C CD  . PRO A 1 127 ? 158.472 144.938 158.259 1.00 79.94  ? 127  PRO A CD  1 
ATOM   965  N N   . PHE A 1 128 ? 154.992 146.150 157.619 1.00 105.73 ? 128  PHE A N   1 
ATOM   966  C CA  . PHE A 1 128 ? 153.800 146.918 157.288 1.00 98.41  ? 128  PHE A CA  1 
ATOM   967  C C   . PHE A 1 128 ? 153.372 146.675 155.850 1.00 99.85  ? 128  PHE A C   1 
ATOM   968  O O   . PHE A 1 128 ? 152.176 146.722 155.545 1.00 94.30  ? 128  PHE A O   1 
ATOM   969  C CB  . PHE A 1 128 ? 154.052 148.405 157.529 1.00 100.96 ? 128  PHE A CB  1 
ATOM   970  C CG  . PHE A 1 128 ? 154.339 148.750 158.966 1.00 105.67 ? 128  PHE A CG  1 
ATOM   971  C CD1 . PHE A 1 128 ? 154.131 147.827 159.979 1.00 102.62 ? 128  PHE A CD1 1 
ATOM   972  C CD2 . PHE A 1 128 ? 154.822 150.002 159.301 1.00 106.48 ? 128  PHE A CD2 1 
ATOM   973  C CE1 . PHE A 1 128 ? 154.396 148.148 161.293 1.00 103.26 ? 128  PHE A CE1 1 
ATOM   974  C CE2 . PHE A 1 128 ? 155.088 150.327 160.615 1.00 107.38 ? 128  PHE A CE2 1 
ATOM   975  C CZ  . PHE A 1 128 ? 154.875 149.399 161.612 1.00 104.69 ? 128  PHE A CZ  1 
ATOM   976  N N   . GLU A 1 129 ? 154.326 146.412 154.956 1.00 110.42 ? 129  GLU A N   1 
ATOM   977  C CA  . GLU A 1 129 ? 153.969 146.036 153.594 1.00 104.43 ? 129  GLU A CA  1 
ATOM   978  C C   . GLU A 1 129 ? 153.192 144.729 153.580 1.00 102.46 ? 129  GLU A C   1 
ATOM   979  O O   . GLU A 1 129 ? 152.208 144.591 152.844 1.00 101.63 ? 129  GLU A O   1 
ATOM   980  C CB  . GLU A 1 129 ? 155.227 145.920 152.737 1.00 103.59 ? 129  GLU A CB  1 
ATOM   981  C CG  . GLU A 1 129 ? 154.957 145.814 151.251 1.00 106.32 ? 129  GLU A CG  1 
ATOM   982  C CD  . GLU A 1 129 ? 156.171 146.172 150.417 1.00 112.85 ? 129  GLU A CD  1 
ATOM   983  O OE1 . GLU A 1 129 ? 156.666 147.311 150.545 1.00 110.11 ? 129  GLU A OE1 1 
ATOM   984  O OE2 . GLU A 1 129 ? 156.631 145.315 149.635 1.00 116.40 ? 129  GLU A OE2 1 
ATOM   985  N N   . ALA A 1 130 ? 153.620 143.756 154.387 1.00 99.13  ? 130  ALA A N   1 
ATOM   986  C CA  . ALA A 1 130 ? 152.883 142.503 154.484 1.00 93.29  ? 130  ALA A CA  1 
ATOM   987  C C   . ALA A 1 130 ? 151.490 142.729 155.050 1.00 93.58  ? 130  ALA A C   1 
ATOM   988  O O   . ALA A 1 130 ? 150.512 142.147 154.566 1.00 92.38  ? 130  ALA A O   1 
ATOM   989  C CB  . ALA A 1 130 ? 153.654 141.508 155.348 1.00 90.19  ? 130  ALA A CB  1 
ATOM   990  N N   . MET A 1 131 ? 151.377 143.569 156.081 1.00 106.62 ? 131  MET A N   1 
ATOM   991  C CA  . MET A 1 131 ? 150.067 143.830 156.668 1.00 107.10 ? 131  MET A CA  1 
ATOM   992  C C   . MET A 1 131 ? 149.137 144.497 155.663 1.00 110.11 ? 131  MET A C   1 
ATOM   993  O O   . MET A 1 131 ? 147.963 144.126 155.549 1.00 112.55 ? 131  MET A O   1 
ATOM   994  C CB  . MET A 1 131 ? 150.214 144.703 157.915 1.00 109.83 ? 131  MET A CB  1 
ATOM   995  C CG  . MET A 1 131 ? 150.781 143.972 159.125 1.00 106.99 ? 131  MET A CG  1 
ATOM   996  S SD  . MET A 1 131 ? 149.554 143.258 160.244 1.00 117.80 ? 131  MET A SD  1 
ATOM   997  C CE  . MET A 1 131 ? 148.452 144.643 160.535 1.00 108.93 ? 131  MET A CE  1 
ATOM   998  N N   . ALA A 1 132 ? 149.647 145.479 154.917 1.00 105.75 ? 132  ALA A N   1 
ATOM   999  C CA  . ALA A 1 132 ? 148.800 146.225 153.992 1.00 105.87 ? 132  ALA A CA  1 
ATOM   1000 C C   . ALA A 1 132 ? 148.266 145.332 152.881 1.00 109.39 ? 132  ALA A C   1 
ATOM   1001 O O   . ALA A 1 132 ? 147.086 145.417 152.523 1.00 110.70 ? 132  ALA A O   1 
ATOM   1002 C CB  . ALA A 1 132 ? 149.579 147.399 153.402 1.00 110.58 ? 132  ALA A CB  1 
ATOM   1003 N N   . GLU A 1 133 ? 149.114 144.472 152.324 1.00 116.24 ? 133  GLU A N   1 
ATOM   1004 C CA  . GLU A 1 133 ? 148.712 143.604 151.226 1.00 115.40 ? 133  GLU A CA  1 
ATOM   1005 C C   . GLU A 1 133 ? 147.987 142.352 151.697 1.00 117.72 ? 133  GLU A C   1 
ATOM   1006 O O   . GLU A 1 133 ? 147.541 141.562 150.859 1.00 115.07 ? 133  GLU A O   1 
ATOM   1007 C CB  . GLU A 1 133 ? 149.936 143.209 150.398 1.00 109.44 ? 133  GLU A CB  1 
ATOM   1008 C CG  . GLU A 1 133 ? 150.350 144.265 149.383 1.00 115.78 ? 133  GLU A CG  1 
ATOM   1009 C CD  . GLU A 1 133 ? 151.851 144.341 149.179 1.00 122.75 ? 133  GLU A CD  1 
ATOM   1010 O OE1 . GLU A 1 133 ? 152.279 144.841 148.118 1.00 123.78 ? 133  GLU A OE1 1 
ATOM   1011 O OE2 . GLU A 1 133 ? 152.606 143.911 150.076 1.00 125.29 ? 133  GLU A OE2 1 
ATOM   1012 N N   . GLY A 1 134 ? 147.861 142.151 153.005 1.00 112.59 ? 134  GLY A N   1 
ATOM   1013 C CA  . GLY A 1 134 ? 147.155 140.990 153.511 1.00 103.81 ? 134  GLY A CA  1 
ATOM   1014 C C   . GLY A 1 134 ? 147.794 139.676 153.132 1.00 105.00 ? 134  GLY A C   1 
ATOM   1015 O O   . GLY A 1 134 ? 147.086 138.685 152.928 1.00 107.21 ? 134  GLY A O   1 
ATOM   1016 N N   . ASN A 1 135 ? 149.120 139.638 153.030 1.00 102.48 ? 135  ASN A N   1 
ATOM   1017 C CA  . ASN A 1 135 ? 149.829 138.397 152.741 1.00 100.95 ? 135  ASN A CA  1 
ATOM   1018 C C   . ASN A 1 135 ? 149.937 137.605 154.037 1.00 96.84  ? 135  ASN A C   1 
ATOM   1019 O O   . ASN A 1 135 ? 150.673 137.990 154.950 1.00 99.74  ? 135  ASN A O   1 
ATOM   1020 C CB  . ASN A 1 135 ? 151.203 138.694 152.147 1.00 99.67  ? 135  ASN A CB  1 
ATOM   1021 C CG  . ASN A 1 135 ? 151.884 137.455 151.590 1.00 99.92  ? 135  ASN A CG  1 
ATOM   1022 O OD1 . ASN A 1 135 ? 153.088 137.274 151.758 1.00 91.16  ? 135  ASN A OD1 1 
ATOM   1023 N ND2 . ASN A 1 135 ? 151.122 136.608 150.907 1.00 105.26 ? 135  ASN A ND2 1 
ATOM   1024 N N   . MET A 1 136 ? 149.200 136.498 154.121 1.00 87.39  ? 136  MET A N   1 
ATOM   1025 C CA  . MET A 1 136 ? 149.043 135.811 155.397 1.00 88.08  ? 136  MET A CA  1 
ATOM   1026 C C   . MET A 1 136 ? 150.360 135.214 155.879 1.00 95.94  ? 136  MET A C   1 
ATOM   1027 O O   . MET A 1 136 ? 150.711 135.334 157.057 1.00 102.87 ? 136  MET A O   1 
ATOM   1028 C CB  . MET A 1 136 ? 147.976 134.724 155.274 1.00 93.75  ? 136  MET A CB  1 
ATOM   1029 C CG  . MET A 1 136 ? 147.192 134.460 156.555 1.00 99.22  ? 136  MET A CG  1 
ATOM   1030 S SD  . MET A 1 136 ? 146.391 135.910 157.273 1.00 104.81 ? 136  MET A SD  1 
ATOM   1031 C CE  . MET A 1 136 ? 145.851 136.784 155.808 1.00 97.36  ? 136  MET A CE  1 
ATOM   1032 N N   . LEU A 1 137 ? 151.102 134.556 154.986 1.00 93.09  ? 137  LEU A N   1 
ATOM   1033 C CA  . LEU A 1 137 ? 152.304 133.848 155.420 1.00 91.29  ? 137  LEU A CA  1 
ATOM   1034 C C   . LEU A 1 137 ? 153.358 134.809 155.952 1.00 89.18  ? 137  LEU A C   1 
ATOM   1035 O O   . LEU A 1 137 ? 154.007 134.528 156.967 1.00 94.01  ? 137  LEU A O   1 
ATOM   1036 C CB  . LEU A 1 137 ? 152.871 133.015 154.272 1.00 87.12  ? 137  LEU A CB  1 
ATOM   1037 C CG  . LEU A 1 137 ? 152.086 131.751 153.916 1.00 92.49  ? 137  LEU A CG  1 
ATOM   1038 C CD1 . LEU A 1 137 ? 152.708 131.060 152.715 1.00 94.84  ? 137  LEU A CD1 1 
ATOM   1039 C CD2 . LEU A 1 137 ? 152.020 130.802 155.102 1.00 89.24  ? 137  LEU A CD2 1 
ATOM   1040 N N   . GLN A 1 138 ? 153.557 135.941 155.278 1.00 84.90  ? 138  GLN A N   1 
ATOM   1041 C CA  . GLN A 1 138 ? 154.530 136.913 155.761 1.00 86.95  ? 138  GLN A CA  1 
ATOM   1042 C C   . GLN A 1 138 ? 154.128 137.454 157.127 1.00 88.58  ? 138  GLN A C   1 
ATOM   1043 O O   . GLN A 1 138 ? 154.968 137.583 158.029 1.00 91.66  ? 138  GLN A O   1 
ATOM   1044 C CB  . GLN A 1 138 ? 154.672 138.050 154.752 1.00 95.84  ? 138  GLN A CB  1 
ATOM   1045 C CG  . GLN A 1 138 ? 155.431 137.666 153.493 1.00 99.17  ? 138  GLN A CG  1 
ATOM   1046 C CD  . GLN A 1 138 ? 155.415 138.760 152.445 1.00 97.73  ? 138  GLN A CD  1 
ATOM   1047 O OE1 . GLN A 1 138 ? 154.932 139.863 152.690 1.00 98.44  ? 138  GLN A OE1 1 
ATOM   1048 N NE2 . GLN A 1 138 ? 155.939 138.455 151.265 1.00 96.35  ? 138  GLN A NE2 1 
ATOM   1049 N N   . ILE A 1 139 ? 152.845 137.774 157.296 1.00 86.67  ? 139  ILE A N   1 
ATOM   1050 C CA  . ILE A 1 139 ? 152.364 138.261 158.584 1.00 84.76  ? 139  ILE A CA  1 
ATOM   1051 C C   . ILE A 1 139 ? 152.607 137.216 159.661 1.00 81.96  ? 139  ILE A C   1 
ATOM   1052 O O   . ILE A 1 139 ? 153.005 137.537 160.784 1.00 88.69  ? 139  ILE A O   1 
ATOM   1053 C CB  . ILE A 1 139 ? 150.876 138.639 158.496 1.00 82.72  ? 139  ILE A CB  1 
ATOM   1054 C CG1 . ILE A 1 139 ? 150.684 139.839 157.569 1.00 92.21  ? 139  ILE A CG1 1 
ATOM   1055 C CG2 . ILE A 1 139 ? 150.328 138.949 159.877 1.00 81.88  ? 139  ILE A CG2 1 
ATOM   1056 C CD1 . ILE A 1 139 ? 149.274 139.980 157.047 1.00 93.67  ? 139  ILE A CD1 1 
ATOM   1057 N N   . ILE A 1 140 ? 152.372 135.946 159.335 1.00 72.28  ? 140  ILE A N   1 
ATOM   1058 C CA  . ILE A 1 140 ? 152.526 134.888 160.328 1.00 73.41  ? 140  ILE A CA  1 
ATOM   1059 C C   . ILE A 1 140 ? 153.992 134.721 160.705 1.00 88.61  ? 140  ILE A C   1 
ATOM   1060 O O   . ILE A 1 140 ? 154.328 134.499 161.872 1.00 98.02  ? 140  ILE A O   1 
ATOM   1061 C CB  . ILE A 1 140 ? 151.923 133.571 159.810 1.00 75.97  ? 140  ILE A CB  1 
ATOM   1062 C CG1 . ILE A 1 140 ? 150.411 133.708 159.645 1.00 78.74  ? 140  ILE A CG1 1 
ATOM   1063 C CG2 . ILE A 1 140 ? 152.229 132.445 160.771 1.00 77.17  ? 140  ILE A CG2 1 
ATOM   1064 C CD1 . ILE A 1 140 ? 149.808 132.675 158.725 1.00 78.44  ? 140  ILE A CD1 1 
ATOM   1065 N N   . VAL A 1 141 ? 154.888 134.812 159.723 1.00 83.10  ? 141  VAL A N   1 
ATOM   1066 C CA  . VAL A 1 141 ? 156.314 134.698 160.021 1.00 71.94  ? 141  VAL A CA  1 
ATOM   1067 C C   . VAL A 1 141 ? 156.750 135.835 160.935 1.00 76.14  ? 141  VAL A C   1 
ATOM   1068 O O   . VAL A 1 141 ? 157.454 135.627 161.936 1.00 84.31  ? 141  VAL A O   1 
ATOM   1069 C CB  . VAL A 1 141 ? 157.136 134.676 158.721 1.00 69.33  ? 141  VAL A CB  1 
ATOM   1070 C CG1 . VAL A 1 141 ? 158.602 134.961 159.015 1.00 74.09  ? 141  VAL A CG1 1 
ATOM   1071 C CG2 . VAL A 1 141 ? 156.977 133.339 158.016 1.00 81.26  ? 141  VAL A CG2 1 
ATOM   1072 N N   . PHE A 1 142 ? 156.338 137.060 160.605 1.00 72.10  ? 142  PHE A N   1 
ATOM   1073 C CA  . PHE A 1 142 ? 156.712 138.190 161.445 1.00 72.38  ? 142  PHE A CA  1 
ATOM   1074 C C   . PHE A 1 142 ? 156.119 138.050 162.840 1.00 74.90  ? 142  PHE A C   1 
ATOM   1075 O O   . PHE A 1 142 ? 156.769 138.389 163.834 1.00 81.01  ? 142  PHE A O   1 
ATOM   1076 C CB  . PHE A 1 142 ? 156.270 139.503 160.808 1.00 70.12  ? 142  PHE A CB  1 
ATOM   1077 C CG  . PHE A 1 142 ? 156.695 140.713 161.582 1.00 66.19  ? 142  PHE A CG  1 
ATOM   1078 C CD1 . PHE A 1 142 ? 158.027 140.914 161.892 1.00 69.14  ? 142  PHE A CD1 1 
ATOM   1079 C CD2 . PHE A 1 142 ? 155.766 141.642 162.009 1.00 73.74  ? 142  PHE A CD2 1 
ATOM   1080 C CE1 . PHE A 1 142 ? 158.426 142.021 162.607 1.00 76.71  ? 142  PHE A CE1 1 
ATOM   1081 C CE2 . PHE A 1 142 ? 156.161 142.753 162.724 1.00 81.13  ? 142  PHE A CE2 1 
ATOM   1082 C CZ  . PHE A 1 142 ? 157.492 142.942 163.024 1.00 78.52  ? 142  PHE A CZ  1 
ATOM   1083 N N   . ALA A 1 143 ? 154.885 137.553 162.933 1.00 71.72  ? 143  ALA A N   1 
ATOM   1084 C CA  . ALA A 1 143 ? 154.263 137.357 164.234 1.00 73.79  ? 143  ALA A CA  1 
ATOM   1085 C C   . ALA A 1 143 ? 154.987 136.294 165.043 1.00 75.78  ? 143  ALA A C   1 
ATOM   1086 O O   . ALA A 1 143 ? 155.093 136.415 166.264 1.00 78.29  ? 143  ALA A O   1 
ATOM   1087 C CB  . ALA A 1 143 ? 152.793 136.981 164.061 1.00 77.20  ? 143  ALA A CB  1 
ATOM   1088 N N   . ILE A 1 144 ? 155.480 135.242 164.390 1.00 76.57  ? 144  ILE A N   1 
ATOM   1089 C CA  . ILE A 1 144 ? 156.249 134.225 165.101 1.00 74.77  ? 144  ILE A CA  1 
ATOM   1090 C C   . ILE A 1 144 ? 157.534 134.828 165.652 1.00 79.59  ? 144  ILE A C   1 
ATOM   1091 O O   . ILE A 1 144 ? 157.907 134.590 166.809 1.00 88.92  ? 144  ILE A O   1 
ATOM   1092 C CB  . ILE A 1 144 ? 156.541 133.029 164.178 1.00 70.22  ? 144  ILE A CB  1 
ATOM   1093 C CG1 . ILE A 1 144 ? 155.274 132.201 163.973 1.00 75.99  ? 144  ILE A CG1 1 
ATOM   1094 C CG2 . ILE A 1 144 ? 157.650 132.169 164.761 1.00 72.64  ? 144  ILE A CG2 1 
ATOM   1095 C CD1 . ILE A 1 144 ? 155.349 131.254 162.801 1.00 79.11  ? 144  ILE A CD1 1 
ATOM   1096 N N   . PHE A 1 145 ? 158.233 135.615 164.832 1.00 65.65  ? 145  PHE A N   1 
ATOM   1097 C CA  . PHE A 1 145 ? 159.430 136.290 165.328 1.00 65.09  ? 145  PHE A CA  1 
ATOM   1098 C C   . PHE A 1 145 ? 159.098 137.184 166.515 1.00 69.80  ? 145  PHE A C   1 
ATOM   1099 O O   . PHE A 1 145 ? 159.798 137.168 167.536 1.00 80.73  ? 145  PHE A O   1 
ATOM   1100 C CB  . PHE A 1 145 ? 160.078 137.106 164.212 1.00 66.56  ? 145  PHE A CB  1 
ATOM   1101 C CG  . PHE A 1 145 ? 161.104 136.348 163.424 1.00 70.79  ? 145  PHE A CG  1 
ATOM   1102 C CD1 . PHE A 1 145 ? 162.335 136.051 163.978 1.00 66.92  ? 145  PHE A CD1 1 
ATOM   1103 C CD2 . PHE A 1 145 ? 160.839 135.934 162.132 1.00 70.80  ? 145  PHE A CD2 1 
ATOM   1104 C CE1 . PHE A 1 145 ? 163.282 135.356 163.258 1.00 68.83  ? 145  PHE A CE1 1 
ATOM   1105 C CE2 . PHE A 1 145 ? 161.784 135.237 161.408 1.00 64.60  ? 145  PHE A CE2 1 
ATOM   1106 C CZ  . PHE A 1 145 ? 163.006 134.948 161.972 1.00 69.09  ? 145  PHE A CZ  1 
ATOM   1107 N N   . PHE A 1 146 ? 158.023 137.963 166.401 1.00 73.82  ? 146  PHE A N   1 
ATOM   1108 C CA  . PHE A 1 146 ? 157.634 138.865 167.478 1.00 78.23  ? 146  PHE A CA  1 
ATOM   1109 C C   . PHE A 1 146 ? 157.295 138.095 168.747 1.00 83.00  ? 146  PHE A C   1 
ATOM   1110 O O   . PHE A 1 146 ? 157.679 138.500 169.849 1.00 97.34  ? 146  PHE A O   1 
ATOM   1111 C CB  . PHE A 1 146 ? 156.441 139.710 167.031 1.00 81.68  ? 146  PHE A CB  1 
ATOM   1112 C CG  . PHE A 1 146 ? 156.452 141.118 167.553 1.00 73.13  ? 146  PHE A CG  1 
ATOM   1113 C CD1 . PHE A 1 146 ? 155.281 141.704 167.995 1.00 77.11  ? 146  PHE A CD1 1 
ATOM   1114 C CD2 . PHE A 1 146 ? 157.617 141.861 167.584 1.00 80.67  ? 146  PHE A CD2 1 
ATOM   1115 C CE1 . PHE A 1 146 ? 155.276 142.997 168.471 1.00 87.13  ? 146  PHE A CE1 1 
ATOM   1116 C CE2 . PHE A 1 146 ? 157.617 143.153 168.061 1.00 94.81  ? 146  PHE A CE2 1 
ATOM   1117 C CZ  . PHE A 1 146 ? 156.444 143.722 168.502 1.00 92.91  ? 146  PHE A CZ  1 
ATOM   1118 N N   . GLY A 1 147 ? 156.563 136.991 168.612 1.00 67.55  ? 147  GLY A N   1 
ATOM   1119 C CA  . GLY A 1 147 ? 156.194 136.213 169.778 1.00 71.07  ? 147  GLY A CA  1 
ATOM   1120 C C   . GLY A 1 147 ? 157.395 135.595 170.459 1.00 74.76  ? 147  GLY A C   1 
ATOM   1121 O O   . GLY A 1 147 ? 157.475 135.571 171.688 1.00 81.95  ? 147  GLY A O   1 
ATOM   1122 N N   . ILE A 1 148 ? 158.344 135.080 169.676 1.00 76.41  ? 148  ILE A N   1 
ATOM   1123 C CA  . ILE A 1 148 ? 159.560 134.540 170.274 1.00 77.19  ? 148  ILE A CA  1 
ATOM   1124 C C   . ILE A 1 148 ? 160.306 135.637 171.020 1.00 78.21  ? 148  ILE A C   1 
ATOM   1125 O O   . ILE A 1 148 ? 160.750 135.446 172.161 1.00 78.38  ? 148  ILE A O   1 
ATOM   1126 C CB  . ILE A 1 148 ? 160.440 133.884 169.196 1.00 71.40  ? 148  ILE A CB  1 
ATOM   1127 C CG1 . ILE A 1 148 ? 159.826 132.556 168.757 1.00 69.10  ? 148  ILE A CG1 1 
ATOM   1128 C CG2 . ILE A 1 148 ? 161.845 133.668 169.724 1.00 73.21  ? 148  ILE A CG2 1 
ATOM   1129 C CD1 . ILE A 1 148 ? 160.379 132.032 167.456 1.00 85.17  ? 148  ILE A CD1 1 
ATOM   1130 N N   . ALA A 1 149 ? 160.440 136.809 170.396 1.00 83.83  ? 149  ALA A N   1 
ATOM   1131 C CA  . ALA A 1 149 ? 161.112 137.917 171.062 1.00 86.73  ? 149  ALA A CA  1 
ATOM   1132 C C   . ALA A 1 149 ? 160.433 138.246 172.385 1.00 89.40  ? 149  ALA A C   1 
ATOM   1133 O O   . ALA A 1 149 ? 161.090 138.344 173.427 1.00 89.87  ? 149  ALA A O   1 
ATOM   1134 C CB  . ALA A 1 149 ? 161.134 139.141 170.148 1.00 88.47  ? 149  ALA A CB  1 
ATOM   1135 N N   . LEU A 1 150 ? 159.106 138.391 172.367 1.00 95.94  ? 150  LEU A N   1 
ATOM   1136 C CA  . LEU A 1 150 ? 158.384 138.730 173.589 1.00 94.81  ? 150  LEU A CA  1 
ATOM   1137 C C   . LEU A 1 150 ? 158.542 137.650 174.647 1.00 96.06  ? 150  LEU A C   1 
ATOM   1138 O O   . LEU A 1 150 ? 158.714 137.961 175.830 1.00 101.51 ? 150  LEU A O   1 
ATOM   1139 C CB  . LEU A 1 150 ? 156.904 138.950 173.285 1.00 90.25  ? 150  LEU A CB  1 
ATOM   1140 C CG  . LEU A 1 150 ? 156.470 140.397 173.058 1.00 94.02  ? 150  LEU A CG  1 
ATOM   1141 C CD1 . LEU A 1 150 ? 157.475 141.133 172.190 1.00 98.67  ? 150  LEU A CD1 1 
ATOM   1142 C CD2 . LEU A 1 150 ? 155.088 140.442 172.437 1.00 95.03  ? 150  LEU A CD2 1 
ATOM   1143 N N   . ALA A 1 151 ? 158.487 136.381 174.246 1.00 87.52  ? 151  ALA A N   1 
ATOM   1144 C CA  . ALA A 1 151 ? 158.667 135.301 175.205 1.00 85.76  ? 151  ALA A CA  1 
ATOM   1145 C C   . ALA A 1 151 ? 160.043 135.358 175.848 1.00 85.10  ? 151  ALA A C   1 
ATOM   1146 O O   . ALA A 1 151 ? 160.180 135.064 177.040 1.00 87.76  ? 151  ALA A O   1 
ATOM   1147 C CB  . ALA A 1 151 ? 158.461 133.951 174.520 1.00 84.99  ? 151  ALA A CB  1 
ATOM   1148 N N   . LEU A 1 152 ? 161.067 135.740 175.087 1.00 83.81  ? 152  LEU A N   1 
ATOM   1149 C CA  . LEU A 1 152 ? 162.421 135.803 175.618 1.00 87.72  ? 152  LEU A CA  1 
ATOM   1150 C C   . LEU A 1 152 ? 162.799 137.160 176.188 1.00 92.60  ? 152  LEU A C   1 
ATOM   1151 O O   . LEU A 1 152 ? 163.648 137.218 177.078 1.00 89.55  ? 152  LEU A O   1 
ATOM   1152 C CB  . LEU A 1 152 ? 163.435 135.429 174.532 1.00 88.80  ? 152  LEU A CB  1 
ATOM   1153 C CG  . LEU A 1 152 ? 163.281 134.022 173.954 1.00 90.22  ? 152  LEU A CG  1 
ATOM   1154 C CD1 . LEU A 1 152 ? 164.232 133.820 172.791 1.00 93.17  ? 152  LEU A CD1 1 
ATOM   1155 C CD2 . LEU A 1 152 ? 163.515 132.975 175.029 1.00 86.23  ? 152  LEU A CD2 1 
ATOM   1156 N N   . MET A 1 153 ? 162.193 138.251 175.714 1.00 104.89 ? 153  MET A N   1 
ATOM   1157 C CA  . MET A 1 153 ? 162.602 139.573 176.172 1.00 104.19 ? 153  MET A CA  1 
ATOM   1158 C C   . MET A 1 153 ? 162.405 139.756 177.671 1.00 106.85 ? 153  MET A C   1 
ATOM   1159 O O   . MET A 1 153 ? 163.220 140.434 178.305 1.00 110.07 ? 153  MET A O   1 
ATOM   1160 C CB  . MET A 1 153 ? 161.830 140.659 175.416 1.00 95.64  ? 153  MET A CB  1 
ATOM   1161 C CG  . MET A 1 153 ? 162.680 141.848 174.979 1.00 95.81  ? 153  MET A CG  1 
ATOM   1162 S SD  . MET A 1 153 ? 161.856 142.857 173.727 1.00 117.02 ? 153  MET A SD  1 
ATOM   1163 C CE  . MET A 1 153 ? 163.061 144.156 173.460 1.00 96.36  ? 153  MET A CE  1 
ATOM   1164 N N   . GLY A 1 154 ? 161.360 139.169 178.248 1.00 102.97 ? 154  GLY A N   1 
ATOM   1165 C CA  . GLY A 1 154 ? 161.194 139.168 179.688 1.00 97.53  ? 154  GLY A CA  1 
ATOM   1166 C C   . GLY A 1 154 ? 160.424 140.345 180.250 1.00 101.03 ? 154  GLY A C   1 
ATOM   1167 O O   . GLY A 1 154 ? 159.351 140.697 179.754 1.00 100.10 ? 154  GLY A O   1 
ATOM   1168 N N   . GLU A 1 155 ? 160.976 140.961 181.298 1.00 112.20 ? 155  GLU A N   1 
ATOM   1169 C CA  . GLU A 1 155 ? 160.246 141.985 182.040 1.00 115.45 ? 155  GLU A CA  1 
ATOM   1170 C C   . GLU A 1 155 ? 159.916 143.191 181.168 1.00 115.31 ? 155  GLU A C   1 
ATOM   1171 O O   . GLU A 1 155 ? 158.805 143.728 181.234 1.00 113.61 ? 155  GLU A O   1 
ATOM   1172 C CB  . GLU A 1 155 ? 161.067 142.412 183.259 1.00 113.23 ? 155  GLU A CB  1 
ATOM   1173 C CG  . GLU A 1 155 ? 160.613 143.704 183.924 1.00 112.45 ? 155  GLU A CG  1 
ATOM   1174 C CD  . GLU A 1 155 ? 161.503 144.094 185.085 1.00 118.52 ? 155  GLU A CD  1 
ATOM   1175 O OE1 . GLU A 1 155 ? 161.637 143.289 186.030 1.00 121.33 ? 155  GLU A OE1 1 
ATOM   1176 O OE2 . GLU A 1 155 ? 162.073 145.205 185.051 1.00 118.98 ? 155  GLU A OE2 1 
ATOM   1177 N N   . LYS A 1 156 ? 160.868 143.635 180.348 1.00 106.85 ? 156  LYS A N   1 
ATOM   1178 C CA  . LYS A 1 156 ? 160.677 144.863 179.586 1.00 100.99 ? 156  LYS A CA  1 
ATOM   1179 C C   . LYS A 1 156 ? 159.605 144.726 178.514 1.00 100.99 ? 156  LYS A C   1 
ATOM   1180 O O   . LYS A 1 156 ? 159.195 145.738 177.937 1.00 101.76 ? 156  LYS A O   1 
ATOM   1181 C CB  . LYS A 1 156 ? 161.997 145.289 178.948 1.00 102.66 ? 156  LYS A CB  1 
ATOM   1182 C CG  . LYS A 1 156 ? 163.071 145.651 179.957 1.00 104.25 ? 156  LYS A CG  1 
ATOM   1183 C CD  . LYS A 1 156 ? 164.455 145.623 179.338 1.00 104.00 ? 156  LYS A CD  1 
ATOM   1184 C CE  . LYS A 1 156 ? 165.528 145.843 180.388 1.00 106.22 ? 156  LYS A CE  1 
ATOM   1185 N NZ  . LYS A 1 156 ? 166.895 145.837 179.801 1.00 105.93 ? 156  LYS A NZ  1 
ATOM   1186 N N   . ALA A 1 157 ? 159.145 143.507 178.232 1.00 96.60  ? 157  ALA A N   1 
ATOM   1187 C CA  . ALA A 1 157 ? 158.138 143.306 177.199 1.00 99.75  ? 157  ALA A CA  1 
ATOM   1188 C C   . ALA A 1 157 ? 156.715 143.385 177.734 1.00 104.25 ? 157  ALA A C   1 
ATOM   1189 O O   . ALA A 1 157 ? 155.770 143.177 176.966 1.00 106.92 ? 157  ALA A O   1 
ATOM   1190 C CB  . ALA A 1 157 ? 158.348 141.953 176.520 1.00 99.30  ? 157  ALA A CB  1 
ATOM   1191 N N   . GLU A 1 158 ? 156.537 143.674 179.021 1.00 108.30 ? 158  GLU A N   1 
ATOM   1192 C CA  . GLU A 1 158 ? 155.191 143.690 179.586 1.00 104.27 ? 158  GLU A CA  1 
ATOM   1193 C C   . GLU A 1 158 ? 154.248 144.631 178.851 1.00 103.97 ? 158  GLU A C   1 
ATOM   1194 O O   . GLU A 1 158 ? 153.105 144.224 178.581 1.00 105.65 ? 158  GLU A O   1 
ATOM   1195 C CB  . GLU A 1 158 ? 155.260 144.049 181.074 1.00 99.75  ? 158  GLU A CB  1 
ATOM   1196 C CG  . GLU A 1 158 ? 155.723 142.904 181.953 1.00 108.79 ? 158  GLU A CG  1 
ATOM   1197 C CD  . GLU A 1 158 ? 154.732 141.759 181.979 1.00 112.09 ? 158  GLU A CD  1 
ATOM   1198 O OE1 . GLU A 1 158 ? 153.535 142.016 182.223 1.00 114.96 ? 158  GLU A OE1 1 
ATOM   1199 O OE2 . GLU A 1 158 ? 155.148 140.604 181.751 1.00 113.19 ? 158  GLU A OE2 1 
ATOM   1200 N N   . PRO A 1 159 ? 154.626 145.865 178.513 1.00 83.20  ? 159  PRO A N   1 
ATOM   1201 C CA  . PRO A 1 159 ? 153.684 146.732 177.790 1.00 82.53  ? 159  PRO A CA  1 
ATOM   1202 C C   . PRO A 1 159 ? 153.180 146.123 176.495 1.00 87.42  ? 159  PRO A C   1 
ATOM   1203 O O   . PRO A 1 159 ? 151.963 146.073 176.277 1.00 88.63  ? 159  PRO A O   1 
ATOM   1204 C CB  . PRO A 1 159 ? 154.506 148.003 177.536 1.00 78.41  ? 159  PRO A CB  1 
ATOM   1205 C CG  . PRO A 1 159 ? 155.541 148.003 178.596 1.00 78.22  ? 159  PRO A CG  1 
ATOM   1206 C CD  . PRO A 1 159 ? 155.879 146.566 178.840 1.00 84.87  ? 159  PRO A CD  1 
ATOM   1207 N N   . VAL A 1 160 ? 154.078 145.648 175.634 1.00 87.34  ? 160  VAL A N   1 
ATOM   1208 C CA  . VAL A 1 160 ? 153.666 145.082 174.354 1.00 86.41  ? 160  VAL A CA  1 
ATOM   1209 C C   . VAL A 1 160 ? 152.831 143.826 174.565 1.00 90.76  ? 160  VAL A C   1 
ATOM   1210 O O   . VAL A 1 160 ? 151.805 143.622 173.904 1.00 99.95  ? 160  VAL A O   1 
ATOM   1211 C CB  . VAL A 1 160 ? 154.898 144.789 173.480 1.00 87.03  ? 160  VAL A CB  1 
ATOM   1212 C CG1 . VAL A 1 160 ? 154.467 144.456 172.066 1.00 87.99  ? 160  VAL A CG1 1 
ATOM   1213 C CG2 . VAL A 1 160 ? 155.857 145.971 173.491 1.00 90.91  ? 160  VAL A CG2 1 
ATOM   1214 N N   . LYS A 1 161 ? 153.273 142.956 175.475 1.00 90.46  ? 161  LYS A N   1 
ATOM   1215 C CA  . LYS A 1 161 ? 152.546 141.719 175.725 1.00 90.48  ? 161  LYS A CA  1 
ATOM   1216 C C   . LYS A 1 161 ? 151.121 142.009 176.171 1.00 98.32  ? 161  LYS A C   1 
ATOM   1217 O O   . LYS A 1 161 ? 150.165 141.430 175.647 1.00 104.03 ? 161  LYS A O   1 
ATOM   1218 C CB  . LYS A 1 161 ? 153.280 140.888 176.776 1.00 92.58  ? 161  LYS A CB  1 
ATOM   1219 C CG  . LYS A 1 161 ? 152.697 139.501 176.993 1.00 97.78  ? 161  LYS A CG  1 
ATOM   1220 C CD  . LYS A 1 161 ? 153.145 138.914 178.320 1.00 98.19  ? 161  LYS A CD  1 
ATOM   1221 C CE  . LYS A 1 161 ? 154.642 138.651 178.343 1.00 100.13 ? 161  LYS A CE  1 
ATOM   1222 N NZ  . LYS A 1 161 ? 155.113 138.246 179.694 1.00 100.71 ? 161  LYS A NZ  1 
ATOM   1223 N N   . LYS A 1 162 ? 150.961 142.910 177.142 1.00 91.72  ? 162  LYS A N   1 
ATOM   1224 C CA  . LYS A 1 162 ? 149.624 143.247 177.615 1.00 88.70  ? 162  LYS A CA  1 
ATOM   1225 C C   . LYS A 1 162 ? 148.795 143.905 176.524 1.00 90.73  ? 162  LYS A C   1 
ATOM   1226 O O   . LYS A 1 162 ? 147.604 143.600 176.383 1.00 98.92  ? 162  LYS A O   1 
ATOM   1227 C CB  . LYS A 1 162 ? 149.714 144.164 178.832 1.00 86.30  ? 162  LYS A CB  1 
ATOM   1228 C CG  . LYS A 1 162 ? 150.070 143.444 180.117 1.00 87.46  ? 162  LYS A CG  1 
ATOM   1229 C CD  . LYS A 1 162 ? 149.902 144.350 181.323 1.00 92.45  ? 162  LYS A CD  1 
ATOM   1230 C CE  . LYS A 1 162 ? 149.980 143.568 182.623 1.00 94.94  ? 162  LYS A CE  1 
ATOM   1231 N NZ  . LYS A 1 162 ? 151.385 143.400 183.084 1.00 97.51  ? 162  LYS A NZ  1 
ATOM   1232 N N   . PHE A 1 163 ? 149.396 144.805 175.743 1.00 68.84  ? 163  PHE A N   1 
ATOM   1233 C CA  . PHE A 1 163 ? 148.645 145.465 174.684 1.00 71.12  ? 163  PHE A CA  1 
ATOM   1234 C C   . PHE A 1 163 ? 148.094 144.449 173.697 1.00 74.39  ? 163  PHE A C   1 
ATOM   1235 O O   . PHE A 1 163 ? 146.913 144.495 173.343 1.00 88.50  ? 163  PHE A O   1 
ATOM   1236 C CB  . PHE A 1 163 ? 149.525 146.480 173.959 1.00 73.75  ? 163  PHE A CB  1 
ATOM   1237 C CG  . PHE A 1 163 ? 148.838 147.149 172.806 1.00 68.09  ? 163  PHE A CG  1 
ATOM   1238 C CD1 . PHE A 1 163 ? 148.064 148.275 173.004 1.00 72.06  ? 163  PHE A CD1 1 
ATOM   1239 C CD2 . PHE A 1 163 ? 148.954 146.641 171.525 1.00 71.17  ? 163  PHE A CD2 1 
ATOM   1240 C CE1 . PHE A 1 163 ? 147.429 148.888 171.947 1.00 81.17  ? 163  PHE A CE1 1 
ATOM   1241 C CE2 . PHE A 1 163 ? 148.319 147.249 170.465 1.00 72.09  ? 163  PHE A CE2 1 
ATOM   1242 C CZ  . PHE A 1 163 ? 147.556 148.373 170.676 1.00 79.32  ? 163  PHE A CZ  1 
ATOM   1243 N N   . PHE A 1 164 ? 148.930 143.517 173.244 1.00 76.09  ? 164  PHE A N   1 
ATOM   1244 C CA  . PHE A 1 164 ? 148.453 142.550 172.263 1.00 80.45  ? 164  PHE A CA  1 
ATOM   1245 C C   . PHE A 1 164 ? 147.519 141.518 172.882 1.00 85.27  ? 164  PHE A C   1 
ATOM   1246 O O   . PHE A 1 164 ? 146.592 141.050 172.209 1.00 94.50  ? 164  PHE A O   1 
ATOM   1247 C CB  . PHE A 1 164 ? 149.636 141.874 171.575 1.00 79.08  ? 164  PHE A CB  1 
ATOM   1248 C CG  . PHE A 1 164 ? 150.299 142.743 170.548 1.00 76.47  ? 164  PHE A CG  1 
ATOM   1249 C CD1 . PHE A 1 164 ? 149.632 143.086 169.387 1.00 73.89  ? 164  PHE A CD1 1 
ATOM   1250 C CD2 . PHE A 1 164 ? 151.575 143.233 170.748 1.00 84.18  ? 164  PHE A CD2 1 
ATOM   1251 C CE1 . PHE A 1 164 ? 150.230 143.891 168.442 1.00 77.18  ? 164  PHE A CE1 1 
ATOM   1252 C CE2 . PHE A 1 164 ? 152.175 144.040 169.804 1.00 82.82  ? 164  PHE A CE2 1 
ATOM   1253 C CZ  . PHE A 1 164 ? 151.502 144.368 168.651 1.00 81.82  ? 164  PHE A CZ  1 
ATOM   1254 N N   . ASP A 1 165 ? 147.713 141.171 174.155 1.00 84.69  ? 165  ASP A N   1 
ATOM   1255 C CA  . ASP A 1 165 ? 146.763 140.292 174.822 1.00 89.82  ? 165  ASP A CA  1 
ATOM   1256 C C   . ASP A 1 165 ? 145.381 140.924 174.883 1.00 93.76  ? 165  ASP A C   1 
ATOM   1257 O O   . ASP A 1 165 ? 144.387 140.237 174.631 1.00 98.49  ? 165  ASP A O   1 
ATOM   1258 C CB  . ASP A 1 165 ? 147.281 139.953 176.224 1.00 88.89  ? 165  ASP A CB  1 
ATOM   1259 C CG  . ASP A 1 165 ? 146.282 139.169 177.070 1.00 96.91  ? 165  ASP A CG  1 
ATOM   1260 O OD1 . ASP A 1 165 ? 146.744 138.351 177.891 1.00 95.79  ? 165  ASP A OD1 1 
ATOM   1261 O OD2 . ASP A 1 165 ? 145.056 139.366 176.950 1.00 104.04 ? 165  ASP A OD2 1 
ATOM   1262 N N   . SER A 1 166 ? 145.296 142.215 175.197 1.00 83.30  ? 166  SER A N   1 
ATOM   1263 C CA  . SER A 1 166 ? 144.012 142.906 175.182 1.00 79.62  ? 166  SER A CA  1 
ATOM   1264 C C   . SER A 1 166 ? 143.472 143.083 173.768 1.00 80.46  ? 166  SER A C   1 
ATOM   1265 O O   . SER A 1 166 ? 142.257 143.011 173.555 1.00 97.77  ? 166  SER A O   1 
ATOM   1266 C CB  . SER A 1 166 ? 144.140 144.270 175.862 1.00 83.96  ? 166  SER A CB  1 
ATOM   1267 O OG  . SER A 1 166 ? 143.017 145.083 175.574 1.00 85.20  ? 166  SER A OG  1 
ATOM   1268 N N   . ALA A 1 167 ? 144.352 143.318 172.793 1.00 77.81  ? 167  ALA A N   1 
ATOM   1269 C CA  . ALA A 1 167 ? 143.902 143.491 171.417 1.00 81.35  ? 167  ALA A CA  1 
ATOM   1270 C C   . ALA A 1 167 ? 143.276 142.213 170.877 1.00 89.00  ? 167  ALA A C   1 
ATOM   1271 O O   . ALA A 1 167 ? 142.286 142.261 170.141 1.00 94.51  ? 167  ALA A O   1 
ATOM   1272 C CB  . ALA A 1 167 ? 145.071 143.927 170.534 1.00 87.36  ? 167  ALA A CB  1 
ATOM   1273 N N   . SER A 1 168 ? 143.847 141.057 171.219 1.00 87.14  ? 168  SER A N   1 
ATOM   1274 C CA  . SER A 1 168 ? 143.256 139.798 170.780 1.00 80.50  ? 168  SER A CA  1 
ATOM   1275 C C   . SER A 1 168 ? 141.843 139.637 171.329 1.00 89.34  ? 168  SER A C   1 
ATOM   1276 O O   . SER A 1 168 ? 140.928 139.225 170.604 1.00 101.76 ? 168  SER A O   1 
ATOM   1277 C CB  . SER A 1 168 ? 144.136 138.629 171.216 1.00 84.55  ? 168  SER A CB  1 
ATOM   1278 O OG  . SER A 1 168 ? 144.448 138.717 172.594 1.00 95.78  ? 168  SER A OG  1 
ATOM   1279 N N   . GLU A 1 169 ? 141.644 139.961 172.607 1.00 83.30  ? 169  GLU A N   1 
ATOM   1280 C CA  . GLU A 1 169 ? 140.309 139.885 173.188 1.00 79.24  ? 169  GLU A CA  1 
ATOM   1281 C C   . GLU A 1 169 ? 139.366 140.873 172.517 1.00 82.01  ? 169  GLU A C   1 
ATOM   1282 O O   . GLU A 1 169 ? 138.184 140.577 172.308 1.00 90.76  ? 169  GLU A O   1 
ATOM   1283 C CB  . GLU A 1 169 ? 140.375 140.147 174.690 1.00 81.20  ? 169  GLU A CB  1 
ATOM   1284 C CG  . GLU A 1 169 ? 141.189 139.122 175.454 1.00 88.25  ? 169  GLU A CG  1 
ATOM   1285 C CD  . GLU A 1 169 ? 140.371 137.915 175.858 1.00 102.03 ? 169  GLU A CD  1 
ATOM   1286 O OE1 . GLU A 1 169 ? 139.348 137.643 175.196 1.00 101.14 ? 169  GLU A OE1 1 
ATOM   1287 O OE2 . GLU A 1 169 ? 140.751 137.237 176.835 1.00 107.54 ? 169  GLU A OE2 1 
ATOM   1288 N N   . VAL A 1 170 ? 139.869 142.061 172.184 1.00 78.13  ? 170  VAL A N   1 
ATOM   1289 C CA  . VAL A 1 170 ? 139.040 143.043 171.493 1.00 76.43  ? 170  VAL A CA  1 
ATOM   1290 C C   . VAL A 1 170 ? 138.598 142.501 170.140 1.00 80.72  ? 170  VAL A C   1 
ATOM   1291 O O   . VAL A 1 170 ? 137.440 142.658 169.738 1.00 91.87  ? 170  VAL A O   1 
ATOM   1292 C CB  . VAL A 1 170 ? 139.800 144.374 171.350 1.00 80.77  ? 170  VAL A CB  1 
ATOM   1293 C CG1 . VAL A 1 170 ? 139.137 145.260 170.312 1.00 79.68  ? 170  VAL A CG1 1 
ATOM   1294 C CG2 . VAL A 1 170 ? 139.876 145.082 172.690 1.00 86.75  ? 170  VAL A CG2 1 
ATOM   1295 N N   . MET A 1 171 ? 139.515 141.862 169.413 1.00 78.32  ? 171  MET A N   1 
ATOM   1296 C CA  . MET A 1 171 ? 139.150 141.280 168.126 1.00 86.26  ? 171  MET A CA  1 
ATOM   1297 C C   . MET A 1 171 ? 138.146 140.147 168.291 1.00 88.96  ? 171  MET A C   1 
ATOM   1298 O O   . MET A 1 171 ? 137.239 140.001 167.466 1.00 93.91  ? 171  MET A O   1 
ATOM   1299 C CB  . MET A 1 171 ? 140.393 140.782 167.390 1.00 88.58  ? 171  MET A CB  1 
ATOM   1300 C CG  . MET A 1 171 ? 141.427 141.860 167.102 1.00 92.42  ? 171  MET A CG  1 
ATOM   1301 S SD  . MET A 1 171 ? 140.775 143.301 166.238 1.00 93.02  ? 171  MET A SD  1 
ATOM   1302 C CE  . MET A 1 171 ? 139.966 142.534 164.841 1.00 92.78  ? 171  MET A CE  1 
ATOM   1303 N N   . PHE A 1 172 ? 138.290 139.331 169.336 1.00 84.26  ? 172  PHE A N   1 
ATOM   1304 C CA  . PHE A 1 172 ? 137.298 138.288 169.583 1.00 83.39  ? 172  PHE A CA  1 
ATOM   1305 C C   . PHE A 1 172 ? 135.926 138.891 169.859 1.00 89.63  ? 172  PHE A C   1 
ATOM   1306 O O   . PHE A 1 172 ? 134.905 138.386 169.377 1.00 94.53  ? 172  PHE A O   1 
ATOM   1307 C CB  . PHE A 1 172 ? 137.737 137.405 170.748 1.00 87.80  ? 172  PHE A CB  1 
ATOM   1308 C CG  . PHE A 1 172 ? 138.742 136.363 170.368 1.00 88.50  ? 172  PHE A CG  1 
ATOM   1309 C CD1 . PHE A 1 172 ? 138.403 135.345 169.497 1.00 86.77  ? 172  PHE A CD1 1 
ATOM   1310 C CD2 . PHE A 1 172 ? 140.026 136.403 170.876 1.00 91.64  ? 172  PHE A CD2 1 
ATOM   1311 C CE1 . PHE A 1 172 ? 139.326 134.386 169.142 1.00 92.03  ? 172  PHE A CE1 1 
ATOM   1312 C CE2 . PHE A 1 172 ? 140.953 135.448 170.525 1.00 84.29  ? 172  PHE A CE2 1 
ATOM   1313 C CZ  . PHE A 1 172 ? 140.603 134.438 169.657 1.00 91.62  ? 172  PHE A CZ  1 
ATOM   1314 N N   . LYS A 1 173 ? 135.880 139.969 170.640 1.00 82.71  ? 173  LYS A N   1 
ATOM   1315 C CA  . LYS A 1 173 ? 134.610 140.647 170.878 1.00 76.66  ? 173  LYS A CA  1 
ATOM   1316 C C   . LYS A 1 173 ? 134.028 141.183 169.578 1.00 79.27  ? 173  LYS A C   1 
ATOM   1317 O O   . LYS A 1 173 ? 132.819 141.084 169.340 1.00 89.97  ? 173  LYS A O   1 
ATOM   1318 C CB  . LYS A 1 173 ? 134.801 141.778 171.886 1.00 79.25  ? 173  LYS A CB  1 
ATOM   1319 C CG  . LYS A 1 173 ? 133.517 142.493 172.267 1.00 79.98  ? 173  LYS A CG  1 
ATOM   1320 C CD  . LYS A 1 173 ? 132.558 141.572 172.996 1.00 81.89  ? 173  LYS A CD  1 
ATOM   1321 C CE  . LYS A 1 173 ? 131.339 142.328 173.489 1.00 89.67  ? 173  LYS A CE  1 
ATOM   1322 N NZ  . LYS A 1 173 ? 130.391 141.442 174.217 1.00 93.06  ? 173  LYS A NZ  1 
ATOM   1323 N N   . ILE A 1 174 ? 134.874 141.762 168.725 1.00 69.55  ? 174  ILE A N   1 
ATOM   1324 C CA  . ILE A 1 174 ? 134.401 142.255 167.435 1.00 73.05  ? 174  ILE A CA  1 
ATOM   1325 C C   . ILE A 1 174 ? 133.817 141.109 166.621 1.00 79.87  ? 174  ILE A C   1 
ATOM   1326 O O   . ILE A 1 174 ? 132.784 141.259 165.959 1.00 84.67  ? 174  ILE A O   1 
ATOM   1327 C CB  . ILE A 1 174 ? 135.543 142.963 166.681 1.00 68.30  ? 174  ILE A CB  1 
ATOM   1328 C CG1 . ILE A 1 174 ? 135.833 144.322 167.319 1.00 76.14  ? 174  ILE A CG1 1 
ATOM   1329 C CG2 . ILE A 1 174 ? 135.189 143.129 165.213 1.00 67.97  ? 174  ILE A CG2 1 
ATOM   1330 C CD1 . ILE A 1 174 ? 135.008 145.466 166.758 1.00 71.68  ? 174  ILE A CD1 1 
ATOM   1331 N N   . THR A 1 175 ? 134.469 139.946 166.659 1.00 83.34  ? 175  THR A N   1 
ATOM   1332 C CA  . THR A 1 175 ? 133.943 138.777 165.963 1.00 81.03  ? 175  THR A CA  1 
ATOM   1333 C C   . THR A 1 175 ? 132.576 138.395 166.508 1.00 78.66  ? 175  THR A C   1 
ATOM   1334 O O   . THR A 1 175 ? 131.653 138.082 165.747 1.00 81.43  ? 175  THR A O   1 
ATOM   1335 C CB  . THR A 1 175 ? 134.914 137.604 166.099 1.00 74.48  ? 175  THR A CB  1 
ATOM   1336 O OG1 . THR A 1 175 ? 136.213 138.003 165.651 1.00 83.67  ? 175  THR A OG1 1 
ATOM   1337 C CG2 . THR A 1 175 ? 134.438 136.416 165.279 1.00 79.63  ? 175  THR A CG2 1 
ATOM   1338 N N   . ASP A 1 176 ? 132.428 138.417 167.832 1.00 80.01  ? 176  ASP A N   1 
ATOM   1339 C CA  . ASP A 1 176 ? 131.129 138.125 168.425 1.00 81.80  ? 176  ASP A CA  1 
ATOM   1340 C C   . ASP A 1 176 ? 130.075 139.111 167.946 1.00 84.79  ? 176  ASP A C   1 
ATOM   1341 O O   . ASP A 1 176 ? 128.927 138.724 167.706 1.00 90.90  ? 176  ASP A O   1 
ATOM   1342 C CB  . ASP A 1 176 ? 131.223 138.157 169.950 1.00 91.65  ? 176  ASP A CB  1 
ATOM   1343 C CG  . ASP A 1 176 ? 131.636 136.823 170.541 1.00 96.96  ? 176  ASP A CG  1 
ATOM   1344 O OD1 . ASP A 1 176 ? 131.969 136.786 171.744 1.00 94.19  ? 176  ASP A OD1 1 
ATOM   1345 O OD2 . ASP A 1 176 ? 131.629 135.811 169.809 1.00 98.67  ? 176  ASP A OD2 1 
ATOM   1346 N N   . ILE A 1 177 ? 130.446 140.383 167.800 1.00 85.50  ? 177  ILE A N   1 
ATOM   1347 C CA  . ILE A 1 177 ? 129.500 141.377 167.306 1.00 76.70  ? 177  ILE A CA  1 
ATOM   1348 C C   . ILE A 1 177 ? 129.078 141.041 165.883 1.00 82.13  ? 177  ILE A C   1 
ATOM   1349 O O   . ILE A 1 177 ? 127.899 141.152 165.528 1.00 88.88  ? 177  ILE A O   1 
ATOM   1350 C CB  . ILE A 1 177 ? 130.114 142.786 167.387 1.00 69.81  ? 177  ILE A CB  1 
ATOM   1351 C CG1 . ILE A 1 177 ? 130.206 143.266 168.839 1.00 79.59  ? 177  ILE A CG1 1 
ATOM   1352 C CG2 . ILE A 1 177 ? 129.284 143.761 166.577 1.00 71.98  ? 177  ILE A CG2 1 
ATOM   1353 C CD1 . ILE A 1 177 ? 128.892 143.259 169.597 1.00 85.74  ? 177  ILE A CD1 1 
ATOM   1354 N N   . VAL A 1 178 ? 130.033 140.641 165.044 1.00 82.12  ? 178  VAL A N   1 
ATOM   1355 C CA  . VAL A 1 178 ? 129.720 140.348 163.650 1.00 76.42  ? 178  VAL A CA  1 
ATOM   1356 C C   . VAL A 1 178 ? 128.796 139.143 163.549 1.00 84.25  ? 178  VAL A C   1 
ATOM   1357 O O   . VAL A 1 178 ? 127.893 139.107 162.705 1.00 91.06  ? 178  VAL A O   1 
ATOM   1358 C CB  . VAL A 1 178 ? 131.016 140.133 162.850 1.00 72.60  ? 178  VAL A CB  1 
ATOM   1359 C CG1 . VAL A 1 178 ? 130.700 139.565 161.481 1.00 68.34  ? 178  VAL A CG1 1 
ATOM   1360 C CG2 . VAL A 1 178 ? 131.779 141.439 162.723 1.00 77.45  ? 178  VAL A CG2 1 
ATOM   1361 N N   . MET A 1 179 ? 129.000 138.139 164.404 1.00 93.48  ? 179  MET A N   1 
ATOM   1362 C CA  . MET A 1 179 ? 128.229 136.906 164.296 1.00 93.62  ? 179  MET A CA  1 
ATOM   1363 C C   . MET A 1 179 ? 126.733 137.138 164.452 1.00 91.03  ? 179  MET A C   1 
ATOM   1364 O O   . MET A 1 179 ? 125.940 136.316 163.981 1.00 94.06  ? 179  MET A O   1 
ATOM   1365 C CB  . MET A 1 179 ? 128.705 135.898 165.339 1.00 95.61  ? 179  MET A CB  1 
ATOM   1366 C CG  . MET A 1 179 ? 130.065 135.294 165.040 1.00 96.70  ? 179  MET A CG  1 
ATOM   1367 S SD  . MET A 1 179 ? 130.015 134.002 163.783 1.00 104.47 ? 179  MET A SD  1 
ATOM   1368 C CE  . MET A 1 179 ? 130.360 134.938 162.296 1.00 94.72  ? 179  MET A CE  1 
ATOM   1369 N N   . LYS A 1 180 ? 126.323 138.233 165.095 1.00 88.48  ? 180  LYS A N   1 
ATOM   1370 C CA  . LYS A 1 180 ? 124.902 138.552 165.151 1.00 91.39  ? 180  LYS A CA  1 
ATOM   1371 C C   . LYS A 1 180 ? 124.305 138.681 163.759 1.00 99.54  ? 180  LYS A C   1 
ATOM   1372 O O   . LYS A 1 180 ? 123.101 138.463 163.588 1.00 105.88 ? 180  LYS A O   1 
ATOM   1373 C CB  . LYS A 1 180 ? 124.674 139.850 165.927 1.00 93.19  ? 180  LYS A CB  1 
ATOM   1374 C CG  . LYS A 1 180 ? 125.290 139.878 167.315 1.00 99.55  ? 180  LYS A CG  1 
ATOM   1375 C CD  . LYS A 1 180 ? 124.667 138.835 168.224 1.00 98.48  ? 180  LYS A CD  1 
ATOM   1376 C CE  . LYS A 1 180 ? 125.225 138.929 169.634 1.00 100.95 ? 180  LYS A CE  1 
ATOM   1377 N NZ  . LYS A 1 180 ? 126.555 138.273 169.755 1.00 102.10 ? 180  LYS A NZ  1 
ATOM   1378 N N   . PHE A 1 181 ? 125.120 139.032 162.767 1.00 102.99 ? 181  PHE A N   1 
ATOM   1379 C CA  . PHE A 1 181 ? 124.693 139.107 161.379 1.00 100.55 ? 181  PHE A CA  1 
ATOM   1380 C C   . PHE A 1 181 ? 124.932 137.810 160.620 1.00 100.07 ? 181  PHE A C   1 
ATOM   1381 O O   . PHE A 1 181 ? 124.587 137.730 159.436 1.00 106.37 ? 181  PHE A O   1 
ATOM   1382 C CB  . PHE A 1 181 ? 125.429 140.253 160.674 1.00 97.88  ? 181  PHE A CB  1 
ATOM   1383 C CG  . PHE A 1 181 ? 124.897 140.569 159.311 1.00 98.86  ? 181  PHE A CG  1 
ATOM   1384 C CD1 . PHE A 1 181 ? 123.644 141.133 159.157 1.00 101.16 ? 181  PHE A CD1 1 
ATOM   1385 C CD2 . PHE A 1 181 ? 125.651 140.303 158.183 1.00 105.69 ? 181  PHE A CD2 1 
ATOM   1386 C CE1 . PHE A 1 181 ? 123.153 141.426 157.903 1.00 105.10 ? 181  PHE A CE1 1 
ATOM   1387 C CE2 . PHE A 1 181 ? 125.165 140.593 156.927 1.00 109.45 ? 181  PHE A CE2 1 
ATOM   1388 C CZ  . PHE A 1 181 ? 123.914 141.155 156.786 1.00 106.03 ? 181  PHE A CZ  1 
ATOM   1389 N N   . ALA A 1 182 ? 125.502 136.797 161.269 1.00 93.61  ? 182  ALA A N   1 
ATOM   1390 C CA  . ALA A 1 182 ? 125.843 135.567 160.563 1.00 94.55  ? 182  ALA A CA  1 
ATOM   1391 C C   . ALA A 1 182 ? 124.647 134.890 159.910 1.00 96.46  ? 182  ALA A C   1 
ATOM   1392 O O   . ALA A 1 182 ? 124.755 134.522 158.727 1.00 103.26 ? 182  ALA A O   1 
ATOM   1393 C CB  . ALA A 1 182 ? 126.534 134.599 161.530 1.00 99.28  ? 182  ALA A CB  1 
ATOM   1394 N N   . PRO A 1 183 ? 123.518 134.668 160.591 1.00 97.12  ? 183  PRO A N   1 
ATOM   1395 C CA  . PRO A 1 183 ? 122.433 133.924 159.933 1.00 102.67 ? 183  PRO A CA  1 
ATOM   1396 C C   . PRO A 1 183 ? 121.940 134.585 158.662 1.00 104.37 ? 183  PRO A C   1 
ATOM   1397 O O   . PRO A 1 183 ? 121.701 133.893 157.666 1.00 108.50 ? 183  PRO A O   1 
ATOM   1398 C CB  . PRO A 1 183 ? 121.343 133.863 161.012 1.00 103.02 ? 183  PRO A CB  1 
ATOM   1399 C CG  . PRO A 1 183 ? 121.654 134.976 161.939 1.00 101.56 ? 183  PRO A CG  1 
ATOM   1400 C CD  . PRO A 1 183 ? 123.143 135.087 161.951 1.00 98.90  ? 183  PRO A CD  1 
ATOM   1401 N N   . TYR A 1 184 ? 121.807 135.912 158.652 1.00 93.11  ? 184  TYR A N   1 
ATOM   1402 C CA  . TYR A 1 184 ? 121.316 136.585 157.453 1.00 94.78  ? 184  TYR A CA  1 
ATOM   1403 C C   . TYR A 1 184 ? 122.338 136.513 156.327 1.00 95.47  ? 184  TYR A C   1 
ATOM   1404 O O   . TYR A 1 184 ? 121.973 136.329 155.160 1.00 96.46  ? 184  TYR A O   1 
ATOM   1405 C CB  . TYR A 1 184 ? 120.961 138.036 157.772 1.00 93.85  ? 184  TYR A CB  1 
ATOM   1406 C CG  . TYR A 1 184 ? 120.142 138.202 159.030 1.00 93.91  ? 184  TYR A CG  1 
ATOM   1407 C CD1 . TYR A 1 184 ? 119.274 137.207 159.454 1.00 94.00  ? 184  TYR A CD1 1 
ATOM   1408 C CD2 . TYR A 1 184 ? 120.242 139.351 159.798 1.00 101.88 ? 184  TYR A CD2 1 
ATOM   1409 C CE1 . TYR A 1 184 ? 118.529 137.352 160.603 1.00 104.59 ? 184  TYR A CE1 1 
ATOM   1410 C CE2 . TYR A 1 184 ? 119.500 139.506 160.949 1.00 103.68 ? 184  TYR A CE2 1 
ATOM   1411 C CZ  . TYR A 1 184 ? 118.645 138.504 161.347 1.00 108.34 ? 184  TYR A CZ  1 
ATOM   1412 O OH  . TYR A 1 184 ? 117.902 138.653 162.495 1.00 110.95 ? 184  TYR A OH  1 
ATOM   1413 N N   . GLY A 1 185 ? 123.623 136.652 156.654 1.00 100.32 ? 185  GLY A N   1 
ATOM   1414 C CA  . GLY A 1 185 ? 124.646 136.522 155.631 1.00 99.28  ? 185  GLY A CA  1 
ATOM   1415 C C   . GLY A 1 185 ? 124.661 135.139 155.012 1.00 107.33 ? 185  GLY A C   1 
ATOM   1416 O O   . GLY A 1 185 ? 124.773 134.989 153.792 1.00 109.25 ? 185  GLY A O   1 
ATOM   1417 N N   . VAL A 1 186 ? 124.548 134.106 155.848 1.00 106.76 ? 186  VAL A N   1 
ATOM   1418 C CA  . VAL A 1 186 ? 124.513 132.741 155.332 1.00 99.45  ? 186  VAL A CA  1 
ATOM   1419 C C   . VAL A 1 186 ? 123.265 132.530 154.487 1.00 99.14  ? 186  VAL A C   1 
ATOM   1420 O O   . VAL A 1 186 ? 123.308 131.869 153.443 1.00 102.31 ? 186  VAL A O   1 
ATOM   1421 C CB  . VAL A 1 186 ? 124.592 131.728 156.487 1.00 92.53  ? 186  VAL A CB  1 
ATOM   1422 C CG1 . VAL A 1 186 ? 124.189 130.346 156.007 1.00 98.27  ? 186  VAL A CG1 1 
ATOM   1423 C CG2 . VAL A 1 186 ? 125.992 131.703 157.066 1.00 98.44  ? 186  VAL A CG2 1 
ATOM   1424 N N   . PHE A 1 187 ? 122.133 133.076 154.930 1.00 96.10  ? 187  PHE A N   1 
ATOM   1425 C CA  . PHE A 1 187 ? 120.911 132.987 154.141 1.00 98.88  ? 187  PHE A CA  1 
ATOM   1426 C C   . PHE A 1 187 ? 121.113 133.591 152.760 1.00 97.06  ? 187  PHE A C   1 
ATOM   1427 O O   . PHE A 1 187 ? 120.761 132.982 151.744 1.00 101.90 ? 187  PHE A O   1 
ATOM   1428 C CB  . PHE A 1 187 ? 119.772 133.691 154.879 1.00 96.75  ? 187  PHE A CB  1 
ATOM   1429 C CG  . PHE A 1 187 ? 118.573 133.966 154.023 1.00 94.02  ? 187  PHE A CG  1 
ATOM   1430 C CD1 . PHE A 1 187 ? 117.566 133.029 153.900 1.00 100.25 ? 187  PHE A CD1 1 
ATOM   1431 C CD2 . PHE A 1 187 ? 118.448 135.168 153.350 1.00 95.37  ? 187  PHE A CD2 1 
ATOM   1432 C CE1 . PHE A 1 187 ? 116.461 133.281 153.115 1.00 97.68  ? 187  PHE A CE1 1 
ATOM   1433 C CE2 . PHE A 1 187 ? 117.346 135.424 152.564 1.00 96.10  ? 187  PHE A CE2 1 
ATOM   1434 C CZ  . PHE A 1 187 ? 116.351 134.480 152.448 1.00 97.27  ? 187  PHE A CZ  1 
ATOM   1435 N N   . ALA A 1 188 ? 121.682 134.795 152.707 1.00 94.50  ? 188  ALA A N   1 
ATOM   1436 C CA  . ALA A 1 188 ? 121.898 135.449 151.422 1.00 96.86  ? 188  ALA A CA  1 
ATOM   1437 C C   . ALA A 1 188 ? 122.848 134.644 150.548 1.00 93.68  ? 188  ALA A C   1 
ATOM   1438 O O   . ALA A 1 188 ? 122.597 134.462 149.351 1.00 101.66 ? 188  ALA A O   1 
ATOM   1439 C CB  . ALA A 1 188 ? 122.440 136.860 151.639 1.00 106.82 ? 188  ALA A CB  1 
ATOM   1440 N N   . LEU A 1 189 ? 123.945 134.155 151.125 1.00 80.66  ? 189  LEU A N   1 
ATOM   1441 C CA  . LEU A 1 189 ? 124.904 133.388 150.337 1.00 81.11  ? 189  LEU A CA  1 
ATOM   1442 C C   . LEU A 1 189 ? 124.267 132.131 149.765 1.00 87.33  ? 189  LEU A C   1 
ATOM   1443 O O   . LEU A 1 189 ? 124.461 131.813 148.584 1.00 94.92  ? 189  LEU A O   1 
ATOM   1444 C CB  . LEU A 1 189 ? 126.115 133.027 151.193 1.00 85.26  ? 189  LEU A CB  1 
ATOM   1445 C CG  . LEU A 1 189 ? 127.016 134.192 151.593 1.00 87.14  ? 189  LEU A CG  1 
ATOM   1446 C CD1 . LEU A 1 189 ? 127.901 133.799 152.765 1.00 90.27  ? 189  LEU A CD1 1 
ATOM   1447 C CD2 . LEU A 1 189 ? 127.852 134.637 150.411 1.00 82.88  ? 189  LEU A CD2 1 
ATOM   1448 N N   . MET A 1 190 ? 123.511 131.397 150.586 1.00 101.82 ? 190  MET A N   1 
ATOM   1449 C CA  . MET A 1 190 ? 122.889 130.171 150.104 1.00 103.49 ? 190  MET A CA  1 
ATOM   1450 C C   . MET A 1 190 ? 121.848 130.474 149.038 1.00 101.87 ? 190  MET A C   1 
ATOM   1451 O O   . MET A 1 190 ? 121.759 129.771 148.024 1.00 105.87 ? 190  MET A O   1 
ATOM   1452 C CB  . MET A 1 190 ? 122.248 129.407 151.260 1.00 107.28 ? 190  MET A CB  1 
ATOM   1453 C CG  . MET A 1 190 ? 123.195 128.599 152.143 1.00 109.10 ? 190  MET A CG  1 
ATOM   1454 S SD  . MET A 1 190 ? 124.264 127.398 151.321 1.00 116.39 ? 190  MET A SD  1 
ATOM   1455 C CE  . MET A 1 190 ? 125.563 128.420 150.629 1.00 107.51 ? 190  MET A CE  1 
ATOM   1456 N N   . ALA A 1 191 ? 121.031 131.505 149.256 1.00 95.78  ? 191  ALA A N   1 
ATOM   1457 C CA  . ALA A 1 191 ? 120.076 131.893 148.230 1.00 93.77  ? 191  ALA A CA  1 
ATOM   1458 C C   . ALA A 1 191 ? 120.783 132.168 146.914 1.00 97.14  ? 191  ALA A C   1 
ATOM   1459 O O   . ALA A 1 191 ? 120.397 131.630 145.870 1.00 104.10 ? 191  ALA A O   1 
ATOM   1460 C CB  . ALA A 1 191 ? 119.290 133.121 148.680 1.00 101.95 ? 191  ALA A CB  1 
ATOM   1461 N N   . TRP A 1 192 ? 121.834 132.988 146.946 1.00 101.88 ? 192  TRP A N   1 
ATOM   1462 C CA  . TRP A 1 192 ? 122.550 133.312 145.718 1.00 100.79 ? 192  TRP A CA  1 
ATOM   1463 C C   . TRP A 1 192 ? 123.082 132.057 145.045 1.00 96.50  ? 192  TRP A C   1 
ATOM   1464 O O   . TRP A 1 192 ? 122.857 131.839 143.850 1.00 106.05 ? 192  TRP A O   1 
ATOM   1465 C CB  . TRP A 1 192 ? 123.695 134.277 146.015 1.00 101.56 ? 192  TRP A CB  1 
ATOM   1466 C CG  . TRP A 1 192 ? 124.518 134.569 144.809 1.00 95.53  ? 192  TRP A CG  1 
ATOM   1467 C CD1 . TRP A 1 192 ? 124.076 135.059 143.619 1.00 100.94 ? 192  TRP A CD1 1 
ATOM   1468 C CD2 . TRP A 1 192 ? 125.928 134.375 144.666 1.00 98.38  ? 192  TRP A CD2 1 
ATOM   1469 N NE1 . TRP A 1 192 ? 125.124 135.190 142.742 1.00 106.67 ? 192  TRP A NE1 1 
ATOM   1470 C CE2 . TRP A 1 192 ? 126.273 134.776 143.362 1.00 105.83 ? 192  TRP A CE2 1 
ATOM   1471 C CE3 . TRP A 1 192 ? 126.933 133.906 145.514 1.00 101.03 ? 192  TRP A CE3 1 
ATOM   1472 C CZ2 . TRP A 1 192 ? 127.579 134.722 142.886 1.00 107.55 ? 192  TRP A CZ2 1 
ATOM   1473 C CZ3 . TRP A 1 192 ? 128.229 133.853 145.041 1.00 98.39  ? 192  TRP A CZ3 1 
ATOM   1474 C CH2 . TRP A 1 192 ? 128.541 134.258 143.739 1.00 102.97 ? 192  TRP A CH2 1 
ATOM   1475 N N   . THR A 1 193 ? 123.788 131.213 145.799 1.00 92.31  ? 193  THR A N   1 
ATOM   1476 C CA  . THR A 1 193 ? 124.420 130.045 145.195 1.00 101.16 ? 193  THR A CA  1 
ATOM   1477 C C   . THR A 1 193 ? 123.382 129.107 144.592 1.00 102.78 ? 193  THR A C   1 
ATOM   1478 O O   . THR A 1 193 ? 123.508 128.687 143.433 1.00 107.20 ? 193  THR A O   1 
ATOM   1479 C CB  . THR A 1 193 ? 125.263 129.309 146.235 1.00 103.91 ? 193  THR A CB  1 
ATOM   1480 O OG1 . THR A 1 193 ? 126.201 130.217 146.825 1.00 110.66 ? 193  THR A OG1 1 
ATOM   1481 C CG2 . THR A 1 193 ? 126.014 128.158 145.593 1.00 97.89  ? 193  THR A CG2 1 
ATOM   1482 N N   . VAL A 1 194 ? 122.352 128.760 145.366 1.00 96.44  ? 194  VAL A N   1 
ATOM   1483 C CA  . VAL A 1 194 ? 121.363 127.802 144.890 1.00 93.17  ? 194  VAL A CA  1 
ATOM   1484 C C   . VAL A 1 194 ? 120.604 128.365 143.698 1.00 93.91  ? 194  VAL A C   1 
ATOM   1485 O O   . VAL A 1 194 ? 120.375 127.663 142.707 1.00 96.56  ? 194  VAL A O   1 
ATOM   1486 C CB  . VAL A 1 194 ? 120.411 127.408 146.032 1.00 96.34  ? 194  VAL A CB  1 
ATOM   1487 C CG1 . VAL A 1 194 ? 119.313 126.499 145.513 1.00 98.40  ? 194  VAL A CG1 1 
ATOM   1488 C CG2 . VAL A 1 194 ? 121.185 126.728 147.148 1.00 103.00 ? 194  VAL A CG2 1 
ATOM   1489 N N   . GLY A 1 195 ? 120.198 129.634 143.767 1.00 100.40 ? 195  GLY A N   1 
ATOM   1490 C CA  . GLY A 1 195 ? 119.476 130.217 142.653 1.00 105.05 ? 195  GLY A CA  1 
ATOM   1491 C C   . GLY A 1 195 ? 120.313 130.273 141.392 1.00 105.03 ? 195  GLY A C   1 
ATOM   1492 O O   . GLY A 1 195 ? 119.825 129.998 140.294 1.00 106.32 ? 195  GLY A O   1 
ATOM   1493 N N   . LYS A 1 196 ? 121.592 130.626 141.531 1.00 110.13 ? 196  LYS A N   1 
ATOM   1494 C CA  . LYS A 1 196 ? 122.461 130.719 140.365 1.00 111.93 ? 196  LYS A CA  1 
ATOM   1495 C C   . LYS A 1 196 ? 122.679 129.352 139.732 1.00 112.68 ? 196  LYS A C   1 
ATOM   1496 O O   . LYS A 1 196 ? 122.534 129.189 138.515 1.00 109.54 ? 196  LYS A O   1 
ATOM   1497 C CB  . LYS A 1 196 ? 123.798 131.347 140.759 1.00 111.21 ? 196  LYS A CB  1 
ATOM   1498 C CG  . LYS A 1 196 ? 124.824 131.367 139.640 1.00 109.54 ? 196  LYS A CG  1 
ATOM   1499 C CD  . LYS A 1 196 ? 126.105 132.053 140.073 1.00 113.58 ? 196  LYS A CD  1 
ATOM   1500 C CE  . LYS A 1 196 ? 127.218 131.823 139.067 1.00 116.44 ? 196  LYS A CE  1 
ATOM   1501 N NZ  . LYS A 1 196 ? 126.937 132.486 137.764 1.00 117.52 ? 196  LYS A NZ  1 
ATOM   1502 N N   . TYR A 1 197 ? 123.023 128.352 140.541 1.00 108.75 ? 197  TYR A N   1 
ATOM   1503 C CA  . TYR A 1 197 ? 123.449 127.059 140.005 1.00 105.63 ? 197  TYR A CA  1 
ATOM   1504 C C   . TYR A 1 197 ? 122.238 126.140 139.840 1.00 109.34 ? 197  TYR A C   1 
ATOM   1505 O O   . TYR A 1 197 ? 121.889 125.336 140.705 1.00 111.34 ? 197  TYR A O   1 
ATOM   1506 C CB  . TYR A 1 197 ? 124.519 126.449 140.898 1.00 105.30 ? 197  TYR A CB  1 
ATOM   1507 C CG  . TYR A 1 197 ? 125.854 127.133 140.736 1.00 102.83 ? 197  TYR A CG  1 
ATOM   1508 C CD1 . TYR A 1 197 ? 126.609 126.953 139.588 1.00 104.15 ? 197  TYR A CD1 1 
ATOM   1509 C CD2 . TYR A 1 197 ? 126.350 127.975 141.721 1.00 101.39 ? 197  TYR A CD2 1 
ATOM   1510 C CE1 . TYR A 1 197 ? 127.823 127.584 139.428 1.00 113.49 ? 197  TYR A CE1 1 
ATOM   1511 C CE2 . TYR A 1 197 ? 127.565 128.610 141.570 1.00 103.91 ? 197  TYR A CE2 1 
ATOM   1512 C CZ  . TYR A 1 197 ? 128.298 128.412 140.422 1.00 112.98 ? 197  TYR A CZ  1 
ATOM   1513 O OH  . TYR A 1 197 ? 129.511 129.042 140.267 1.00 110.88 ? 197  TYR A OH  1 
ATOM   1514 N N   . GLY A 1 198 ? 121.596 126.278 138.681 1.00 127.01 ? 198  GLY A N   1 
ATOM   1515 C CA  . GLY A 1 198 ? 120.422 125.481 138.385 1.00 126.71 ? 198  GLY A CA  1 
ATOM   1516 C C   . GLY A 1 198 ? 120.772 124.065 137.968 1.00 127.80 ? 198  GLY A C   1 
ATOM   1517 O O   . GLY A 1 198 ? 121.903 123.753 137.597 1.00 132.02 ? 198  GLY A O   1 
ATOM   1518 N N   . LEU A 1 199 ? 119.755 123.200 138.012 1.00 130.62 ? 199  LEU A N   1 
ATOM   1519 C CA  . LEU A 1 199 ? 119.965 121.777 137.759 1.00 130.46 ? 199  LEU A CA  1 
ATOM   1520 C C   . LEU A 1 199 ? 120.690 121.537 136.441 1.00 131.48 ? 199  LEU A C   1 
ATOM   1521 O O   . LEU A 1 199 ? 121.576 120.678 136.359 1.00 131.22 ? 199  LEU A O   1 
ATOM   1522 C CB  . LEU A 1 199 ? 118.624 121.036 137.761 1.00 130.10 ? 199  LEU A CB  1 
ATOM   1523 C CG  . LEU A 1 199 ? 117.612 121.355 136.653 1.00 134.43 ? 199  LEU A CG  1 
ATOM   1524 C CD1 . LEU A 1 199 ? 116.468 120.353 136.691 1.00 132.11 ? 199  LEU A CD1 1 
ATOM   1525 C CD2 . LEU A 1 199 ? 117.072 122.775 136.746 1.00 131.94 ? 199  LEU A CD2 1 
ATOM   1526 N N   . ASP A 1 200 ? 120.326 122.281 135.395 1.00 132.65 ? 200  ASP A N   1 
ATOM   1527 C CA  . ASP A 1 200 ? 120.934 122.065 134.088 1.00 130.92 ? 200  ASP A CA  1 
ATOM   1528 C C   . ASP A 1 200 ? 122.446 122.233 134.137 1.00 131.65 ? 200  ASP A C   1 
ATOM   1529 O O   . ASP A 1 200 ? 123.164 121.498 133.452 1.00 130.81 ? 200  ASP A O   1 
ATOM   1530 C CB  . ASP A 1 200 ? 120.314 123.029 133.070 1.00 130.33 ? 200  ASP A CB  1 
ATOM   1531 C CG  . ASP A 1 200 ? 120.836 122.822 131.653 1.00 131.81 ? 200  ASP A CG  1 
ATOM   1532 O OD1 . ASP A 1 200 ? 120.055 123.051 130.707 1.00 133.79 ? 200  ASP A OD1 1 
ATOM   1533 O OD2 . ASP A 1 200 ? 122.012 122.448 131.471 1.00 131.62 ? 200  ASP A OD2 1 
ATOM   1534 N N   . VAL A 1 201 ? 122.947 123.167 134.947 1.00 120.98 ? 201  VAL A N   1 
ATOM   1535 C CA  . VAL A 1 201 ? 124.385 123.411 134.988 1.00 116.80 ? 201  VAL A CA  1 
ATOM   1536 C C   . VAL A 1 201 ? 125.114 122.231 135.621 1.00 116.77 ? 201  VAL A C   1 
ATOM   1537 O O   . VAL A 1 201 ? 126.202 121.847 135.176 1.00 116.27 ? 201  VAL A O   1 
ATOM   1538 C CB  . VAL A 1 201 ? 124.686 124.724 135.733 1.00 119.70 ? 201  VAL A CB  1 
ATOM   1539 C CG1 . VAL A 1 201 ? 126.061 125.246 135.343 1.00 116.66 ? 201  VAL A CG1 1 
ATOM   1540 C CG2 . VAL A 1 201 ? 123.620 125.772 135.438 1.00 122.46 ? 201  VAL A CG2 1 
ATOM   1541 N N   . LEU A 1 202 ? 124.534 121.638 136.665 1.00 119.23 ? 202  LEU A N   1 
ATOM   1542 C CA  . LEU A 1 202 ? 125.203 120.571 137.402 1.00 119.42 ? 202  LEU A CA  1 
ATOM   1543 C C   . LEU A 1 202 ? 125.160 119.227 136.683 1.00 123.93 ? 202  LEU A C   1 
ATOM   1544 O O   . LEU A 1 202 ? 126.133 118.468 136.742 1.00 125.62 ? 202  LEU A O   1 
ATOM   1545 C CB  . LEU A 1 202 ? 124.583 120.412 138.793 1.00 117.61 ? 202  LEU A CB  1 
ATOM   1546 C CG  . LEU A 1 202 ? 124.801 121.533 139.811 1.00 118.29 ? 202  LEU A CG  1 
ATOM   1547 C CD1 . LEU A 1 202 ? 124.175 122.832 139.352 1.00 120.26 ? 202  LEU A CD1 1 
ATOM   1548 C CD2 . LEU A 1 202 ? 124.240 121.124 141.162 1.00 119.15 ? 202  LEU A CD2 1 
ATOM   1549 N N   . ALA A 1 203 ? 124.057 118.913 136.008 1.00 119.81 ? 203  ALA A N   1 
ATOM   1550 C CA  . ALA A 1 203 ? 123.885 117.573 135.452 1.00 114.81 ? 203  ALA A CA  1 
ATOM   1551 C C   . ALA A 1 203 ? 125.041 117.129 134.567 1.00 116.47 ? 203  ALA A C   1 
ATOM   1552 O O   . ALA A 1 203 ? 125.469 115.969 134.699 1.00 115.52 ? 203  ALA A O   1 
ATOM   1553 C CB  . ALA A 1 203 ? 122.563 117.502 134.675 1.00 112.56 ? 203  ALA A CB  1 
ATOM   1554 N N   . PRO A 1 204 ? 125.583 117.955 133.669 1.00 112.08 ? 204  PRO A N   1 
ATOM   1555 C CA  . PRO A 1 204 ? 126.703 117.484 132.839 1.00 110.15 ? 204  PRO A CA  1 
ATOM   1556 C C   . PRO A 1 204 ? 127.890 116.989 133.644 1.00 105.93 ? 204  PRO A C   1 
ATOM   1557 O O   . PRO A 1 204 ? 128.531 116.010 133.244 1.00 99.09  ? 204  PRO A O   1 
ATOM   1558 C CB  . PRO A 1 204 ? 127.062 118.723 132.008 1.00 109.96 ? 204  PRO A CB  1 
ATOM   1559 C CG  . PRO A 1 204 ? 125.808 119.518 131.962 1.00 108.49 ? 204  PRO A CG  1 
ATOM   1560 C CD  . PRO A 1 204 ? 125.155 119.312 133.293 1.00 106.94 ? 204  PRO A CD  1 
ATOM   1561 N N   . LEU A 1 205 ? 128.204 117.633 134.770 1.00 110.52 ? 205  LEU A N   1 
ATOM   1562 C CA  . LEU A 1 205 ? 129.321 117.235 135.619 1.00 111.27 ? 205  LEU A CA  1 
ATOM   1563 C C   . LEU A 1 205 ? 128.842 116.690 136.960 1.00 111.77 ? 205  LEU A C   1 
ATOM   1564 O O   . LEU A 1 205 ? 129.511 116.875 137.987 1.00 108.01 ? 205  LEU A O   1 
ATOM   1565 C CB  . LEU A 1 205 ? 130.273 118.414 135.826 1.00 110.29 ? 205  LEU A CB  1 
ATOM   1566 C CG  . LEU A 1 205 ? 130.745 119.085 134.533 1.00 109.85 ? 205  LEU A CG  1 
ATOM   1567 C CD1 . LEU A 1 205 ? 131.769 120.164 134.833 1.00 111.73 ? 205  LEU A CD1 1 
ATOM   1568 C CD2 . LEU A 1 205 ? 131.315 118.061 133.564 1.00 108.82 ? 205  LEU A CD2 1 
ATOM   1569 N N   . GLY A 1 206 ? 127.686 116.027 136.967 1.00 117.99 ? 206  GLY A N   1 
ATOM   1570 C CA  . GLY A 1 206 ? 127.179 115.460 138.202 1.00 116.43 ? 206  GLY A CA  1 
ATOM   1571 C C   . GLY A 1 206 ? 128.121 114.436 138.796 1.00 112.96 ? 206  GLY A C   1 
ATOM   1572 O O   . GLY A 1 206 ? 128.282 114.361 140.015 1.00 115.66 ? 206  GLY A O   1 
ATOM   1573 N N   . LYS A 1 207 ? 128.760 113.633 137.945 1.00 103.69 ? 207  LYS A N   1 
ATOM   1574 C CA  . LYS A 1 207 ? 129.691 112.636 138.457 1.00 102.43 ? 207  LYS A CA  1 
ATOM   1575 C C   . LYS A 1 207 ? 130.931 113.282 139.056 1.00 106.61 ? 207  LYS A C   1 
ATOM   1576 O O   . LYS A 1 207 ? 131.441 112.801 140.070 1.00 113.93 ? 207  LYS A O   1 
ATOM   1577 C CB  . LYS A 1 207 ? 130.072 111.650 137.356 1.00 100.72 ? 207  LYS A CB  1 
ATOM   1578 C CG  . LYS A 1 207 ? 129.041 110.554 137.170 1.00 104.10 ? 207  LYS A CG  1 
ATOM   1579 C CD  . LYS A 1 207 ? 129.432 109.573 136.085 1.00 108.71 ? 207  LYS A CD  1 
ATOM   1580 C CE  . LYS A 1 207 ? 128.373 108.495 135.926 1.00 111.02 ? 207  LYS A CE  1 
ATOM   1581 N NZ  . LYS A 1 207 ? 128.730 107.497 134.883 1.00 113.95 ? 207  LYS A NZ  1 
ATOM   1582 N N   . LEU A 1 208 ? 131.429 114.367 138.461 1.00 106.16 ? 208  LEU A N   1 
ATOM   1583 C CA  . LEU A 1 208 ? 132.543 115.081 139.078 1.00 108.94 ? 208  LEU A CA  1 
ATOM   1584 C C   . LEU A 1 208 ? 132.141 115.660 140.429 1.00 108.29 ? 208  LEU A C   1 
ATOM   1585 O O   . LEU A 1 208 ? 132.907 115.584 141.400 1.00 106.29 ? 208  LEU A O   1 
ATOM   1586 C CB  . LEU A 1 208 ? 133.039 116.186 138.148 1.00 107.30 ? 208  LEU A CB  1 
ATOM   1587 C CG  . LEU A 1 208 ? 134.104 117.115 138.733 1.00 100.50 ? 208  LEU A CG  1 
ATOM   1588 C CD1 . LEU A 1 208 ? 135.313 116.325 139.194 1.00 103.40 ? 208  LEU A CD1 1 
ATOM   1589 C CD2 . LEU A 1 208 ? 134.513 118.159 137.712 1.00 103.86 ? 208  LEU A CD2 1 
ATOM   1590 N N   . ILE A 1 209 ? 130.944 116.243 140.510 1.00 105.00 ? 209  ILE A N   1 
ATOM   1591 C CA  . ILE A 1 209 ? 130.479 116.797 141.780 1.00 98.78  ? 209  ILE A CA  1 
ATOM   1592 C C   . ILE A 1 209 ? 130.389 115.694 142.826 1.00 100.80 ? 209  ILE A C   1 
ATOM   1593 O O   . ILE A 1 209 ? 130.826 115.856 143.974 1.00 100.91 ? 209  ILE A O   1 
ATOM   1594 C CB  . ILE A 1 209 ? 129.126 117.504 141.589 1.00 97.61  ? 209  ILE A CB  1 
ATOM   1595 C CG1 . ILE A 1 209 ? 129.327 118.789 140.784 1.00 105.34 ? 209  ILE A CG1 1 
ATOM   1596 C CG2 . ILE A 1 209 ? 128.477 117.788 142.947 1.00 95.91  ? 209  ILE A CG2 1 
ATOM   1597 C CD1 . ILE A 1 209 ? 128.145 119.732 140.783 1.00 109.96 ? 209  ILE A CD1 1 
ATOM   1598 N N   . LEU A 1 210 ? 129.812 114.556 142.440 1.00 108.58 ? 210  LEU A N   1 
ATOM   1599 C CA  . LEU A 1 210 ? 129.685 113.435 143.359 1.00 109.14 ? 210  LEU A CA  1 
ATOM   1600 C C   . LEU A 1 210 ? 131.050 112.931 143.793 1.00 113.25 ? 210  LEU A C   1 
ATOM   1601 O O   . LEU A 1 210 ? 131.251 112.602 144.963 1.00 114.48 ? 210  LEU A O   1 
ATOM   1602 C CB  . LEU A 1 210 ? 128.881 112.311 142.705 1.00 109.36 ? 210  LEU A CB  1 
ATOM   1603 C CG  . LEU A 1 210 ? 128.577 111.101 143.590 1.00 113.87 ? 210  LEU A CG  1 
ATOM   1604 C CD1 . LEU A 1 210 ? 127.202 110.544 143.268 1.00 112.79 ? 210  LEU A CD1 1 
ATOM   1605 C CD2 . LEU A 1 210 ? 129.638 110.020 143.427 1.00 113.07 ? 210  LEU A CD2 1 
ATOM   1606 N N   . THR A 1 211 ? 132.002 112.859 142.863 1.00 102.60 ? 211  THR A N   1 
ATOM   1607 C CA  . THR A 1 211 ? 133.338 112.396 143.216 1.00 95.14  ? 211  THR A CA  1 
ATOM   1608 C C   . THR A 1 211 ? 133.984 113.321 144.235 1.00 96.04  ? 211  THR A C   1 
ATOM   1609 O O   . THR A 1 211 ? 134.568 112.858 145.219 1.00 98.82  ? 211  THR A O   1 
ATOM   1610 C CB  . THR A 1 211 ? 134.209 112.297 141.965 1.00 91.41  ? 211  THR A CB  1 
ATOM   1611 O OG1 . THR A 1 211 ? 133.611 111.389 141.034 1.00 96.61  ? 211  THR A OG1 1 
ATOM   1612 C CG2 . THR A 1 211 ? 135.605 111.810 142.324 1.00 93.10  ? 211  THR A CG2 1 
ATOM   1613 N N   . VAL A 1 212 ? 133.882 114.634 144.024 1.00 94.90  ? 212  VAL A N   1 
ATOM   1614 C CA  . VAL A 1 212 ? 134.510 115.566 144.956 1.00 95.55  ? 212  VAL A CA  1 
ATOM   1615 C C   . VAL A 1 212 ? 133.854 115.474 146.330 1.00 100.02 ? 212  VAL A C   1 
ATOM   1616 O O   . VAL A 1 212 ? 134.540 115.418 147.361 1.00 100.27 ? 212  VAL A O   1 
ATOM   1617 C CB  . VAL A 1 212 ? 134.456 116.999 144.400 1.00 100.42 ? 212  VAL A CB  1 
ATOM   1618 C CG1 . VAL A 1 212 ? 134.927 117.993 145.448 1.00 100.13 ? 212  VAL A CG1 1 
ATOM   1619 C CG2 . VAL A 1 212 ? 135.299 117.108 143.142 1.00 102.71 ? 212  VAL A CG2 1 
ATOM   1620 N N   . TYR A 1 213 ? 132.520 115.458 146.373 1.00 98.45  ? 213  TYR A N   1 
ATOM   1621 C CA  . TYR A 1 213 ? 131.834 115.394 147.660 1.00 95.10  ? 213  TYR A CA  1 
ATOM   1622 C C   . TYR A 1 213 ? 132.122 114.077 148.371 1.00 102.16 ? 213  TYR A C   1 
ATOM   1623 O O   . TYR A 1 213 ? 132.324 114.049 149.591 1.00 106.03 ? 213  TYR A O   1 
ATOM   1624 C CB  . TYR A 1 213 ? 130.333 115.589 147.466 1.00 96.24  ? 213  TYR A CB  1 
ATOM   1625 C CG  . TYR A 1 213 ? 129.922 117.039 147.461 1.00 93.78  ? 213  TYR A CG  1 
ATOM   1626 C CD1 . TYR A 1 213 ? 128.882 117.488 148.260 1.00 99.58  ? 213  TYR A CD1 1 
ATOM   1627 C CD2 . TYR A 1 213 ? 130.583 117.962 146.667 1.00 93.80  ? 213  TYR A CD2 1 
ATOM   1628 C CE1 . TYR A 1 213 ? 128.507 118.813 148.261 1.00 102.46 ? 213  TYR A CE1 1 
ATOM   1629 C CE2 . TYR A 1 213 ? 130.215 119.289 146.662 1.00 97.03  ? 213  TYR A CE2 1 
ATOM   1630 C CZ  . TYR A 1 213 ? 129.178 119.710 147.461 1.00 101.87 ? 213  TYR A CZ  1 
ATOM   1631 O OH  . TYR A 1 213 ? 128.808 121.033 147.459 1.00 109.34 ? 213  TYR A OH  1 
ATOM   1632 N N   . LEU A 1 214 ? 132.138 112.973 147.624 1.00 103.37 ? 214  LEU A N   1 
ATOM   1633 C CA  . LEU A 1 214 ? 132.451 111.679 148.212 1.00 100.91 ? 214  LEU A CA  1 
ATOM   1634 C C   . LEU A 1 214 ? 133.875 111.650 148.738 1.00 101.61 ? 214  LEU A C   1 
ATOM   1635 O O   . LEU A 1 214 ? 134.140 111.063 149.789 1.00 99.21  ? 214  LEU A O   1 
ATOM   1636 C CB  . LEU A 1 214 ? 132.237 110.576 147.177 1.00 98.10  ? 214  LEU A CB  1 
ATOM   1637 C CG  . LEU A 1 214 ? 132.610 109.158 147.605 1.00 99.35  ? 214  LEU A CG  1 
ATOM   1638 C CD1 . LEU A 1 214 ? 131.770 108.718 148.789 1.00 104.56 ? 214  LEU A CD1 1 
ATOM   1639 C CD2 . LEU A 1 214 ? 132.439 108.204 146.437 1.00 99.86  ? 214  LEU A CD2 1 
ATOM   1640 N N   . GLY A 1 215 ? 134.811 112.268 148.019 1.00 101.38 ? 215  GLY A N   1 
ATOM   1641 C CA  . GLY A 1 215 ? 136.170 112.348 148.520 1.00 98.42  ? 215  GLY A CA  1 
ATOM   1642 C C   . GLY A 1 215 ? 136.258 113.129 149.813 1.00 104.07 ? 215  GLY A C   1 
ATOM   1643 O O   . GLY A 1 215 ? 136.944 112.719 150.751 1.00 113.37 ? 215  GLY A O   1 
ATOM   1644 N N   . CYS A 1 216 ? 135.558 114.261 149.887 1.00 98.15  ? 216  CYS A N   1 
ATOM   1645 C CA  . CYS A 1 216 ? 135.561 115.034 151.125 1.00 96.65  ? 216  CYS A CA  1 
ATOM   1646 C C   . CYS A 1 216 ? 134.969 114.228 152.275 1.00 97.18  ? 216  CYS A C   1 
ATOM   1647 O O   . CYS A 1 216 ? 135.526 114.200 153.381 1.00 94.86  ? 216  CYS A O   1 
ATOM   1648 C CB  . CYS A 1 216 ? 134.789 116.336 150.929 1.00 99.19  ? 216  CYS A CB  1 
ATOM   1649 S SG  . CYS A 1 216 ? 135.626 117.532 149.866 1.00 113.62 ? 216  CYS A SG  1 
ATOM   1650 N N   . ILE A 1 217 ? 133.847 113.551 152.028 1.00 99.33  ? 217  ILE A N   1 
ATOM   1651 C CA  . ILE A 1 217 ? 133.200 112.773 153.081 1.00 97.30  ? 217  ILE A CA  1 
ATOM   1652 C C   . ILE A 1 217 ? 134.106 111.630 153.522 1.00 100.86 ? 217  ILE A C   1 
ATOM   1653 O O   . ILE A 1 217 ? 134.244 111.346 154.720 1.00 108.64 ? 217  ILE A O   1 
ATOM   1654 C CB  . ILE A 1 217 ? 131.831 112.259 152.598 1.00 92.70  ? 217  ILE A CB  1 
ATOM   1655 C CG1 . ILE A 1 217 ? 130.876 113.432 152.378 1.00 94.10  ? 217  ILE A CG1 1 
ATOM   1656 C CG2 . ILE A 1 217 ? 131.227 111.310 153.609 1.00 93.02  ? 217  ILE A CG2 1 
ATOM   1657 C CD1 . ILE A 1 217 ? 129.712 113.105 151.468 1.00 100.21 ? 217  ILE A CD1 1 
ATOM   1658 N N   . ILE A 1 218 ? 134.732 110.951 152.559 1.00 99.36  ? 218  ILE A N   1 
ATOM   1659 C CA  . ILE A 1 218 ? 135.630 109.853 152.886 1.00 98.62  ? 218  ILE A CA  1 
ATOM   1660 C C   . ILE A 1 218 ? 136.799 110.361 153.713 1.00 98.34  ? 218  ILE A C   1 
ATOM   1661 O O   . ILE A 1 218 ? 137.200 109.732 154.695 1.00 96.57  ? 218  ILE A O   1 
ATOM   1662 C CB  . ILE A 1 218 ? 136.108 109.158 151.600 1.00 98.73  ? 218  ILE A CB  1 
ATOM   1663 C CG1 . ILE A 1 218 ? 134.992 108.290 151.008 1.00 100.78 ? 218  ILE A CG1 1 
ATOM   1664 C CG2 . ILE A 1 218 ? 137.348 108.318 151.872 1.00 101.49 ? 218  ILE A CG2 1 
ATOM   1665 C CD1 . ILE A 1 218 ? 134.678 107.036 151.803 1.00 102.71 ? 218  ILE A CD1 1 
ATOM   1666 N N   . HIS A 1 219 ? 137.369 111.503 153.328 1.00 97.67  ? 219  HIS A N   1 
ATOM   1667 C CA  . HIS A 1 219 ? 138.438 112.088 154.126 1.00 93.94  ? 219  HIS A CA  1 
ATOM   1668 C C   . HIS A 1 219 ? 137.975 112.333 155.553 1.00 101.39 ? 219  HIS A C   1 
ATOM   1669 O O   . HIS A 1 219 ? 138.657 111.948 156.509 1.00 111.21 ? 219  HIS A O   1 
ATOM   1670 C CB  . HIS A 1 219 ? 138.911 113.392 153.487 1.00 94.37  ? 219  HIS A CB  1 
ATOM   1671 C CG  . HIS A 1 219 ? 140.249 113.851 153.970 1.00 94.80  ? 219  HIS A CG  1 
ATOM   1672 N ND1 . HIS A 1 219 ? 141.424 113.219 153.626 1.00 99.29  ? 219  HIS A ND1 1 
ATOM   1673 C CD2 . HIS A 1 219 ? 140.600 114.888 154.766 1.00 97.69  ? 219  HIS A CD2 1 
ATOM   1674 C CE1 . HIS A 1 219 ? 142.440 113.844 154.192 1.00 101.00 ? 219  HIS A CE1 1 
ATOM   1675 N NE2 . HIS A 1 219 ? 141.967 114.860 154.889 1.00 99.27  ? 219  HIS A NE2 1 
ATOM   1676 N N   . ILE A 1 220 ? 136.798 112.938 155.716 1.00 100.78 ? 220  ILE A N   1 
ATOM   1677 C CA  . ILE A 1 220 ? 136.322 113.272 157.055 1.00 102.54 ? 220  ILE A CA  1 
ATOM   1678 C C   . ILE A 1 220 ? 136.146 112.013 157.895 1.00 111.31 ? 220  ILE A C   1 
ATOM   1679 O O   . ILE A 1 220 ? 136.561 111.966 159.059 1.00 110.57 ? 220  ILE A O   1 
ATOM   1680 C CB  . ILE A 1 220 ? 135.016 114.082 156.975 1.00 97.96  ? 220  ILE A CB  1 
ATOM   1681 C CG1 . ILE A 1 220 ? 135.298 115.474 156.410 1.00 100.17 ? 220  ILE A CG1 1 
ATOM   1682 C CG2 . ILE A 1 220 ? 134.372 114.181 158.349 1.00 96.12  ? 220  ILE A CG2 1 
ATOM   1683 C CD1 . ILE A 1 220 ? 134.058 116.277 156.101 1.00 102.82 ? 220  ILE A CD1 1 
ATOM   1684 N N   . LEU A 1 221 ? 135.530 110.976 157.329 1.00 112.76 ? 221  LEU A N   1 
ATOM   1685 C CA  . LEU A 1 221 ? 135.193 109.798 158.124 1.00 105.84 ? 221  LEU A CA  1 
ATOM   1686 C C   . LEU A 1 221 ? 136.317 108.774 158.221 1.00 101.57 ? 221  LEU A C   1 
ATOM   1687 O O   . LEU A 1 221 ? 136.216 107.847 159.032 1.00 106.26 ? 221  LEU A O   1 
ATOM   1688 C CB  . LEU A 1 221 ? 133.945 109.107 157.565 1.00 101.44 ? 221  LEU A CB  1 
ATOM   1689 C CG  . LEU A 1 221 ? 132.593 109.812 157.735 1.00 99.85  ? 221  LEU A CG  1 
ATOM   1690 C CD1 . LEU A 1 221 ? 132.494 110.518 159.077 1.00 99.53  ? 221  LEU A CD1 1 
ATOM   1691 C CD2 . LEU A 1 221 ? 132.340 110.786 156.616 1.00 105.42 ? 221  LEU A CD2 1 
ATOM   1692 N N   . ILE A 1 222 ? 137.377 108.896 157.427 1.00 99.15  ? 222  ILE A N   1 
ATOM   1693 C CA  . ILE A 1 222 ? 138.444 107.899 157.458 1.00 107.71 ? 222  ILE A CA  1 
ATOM   1694 C C   . ILE A 1 222 ? 139.729 108.468 158.043 1.00 105.23 ? 222  ILE A C   1 
ATOM   1695 O O   . ILE A 1 222 ? 140.454 107.762 158.745 1.00 108.65 ? 222  ILE A O   1 
ATOM   1696 C CB  . ILE A 1 222 ? 138.673 107.330 156.042 1.00 111.73 ? 222  ILE A CB  1 
ATOM   1697 C CG1 . ILE A 1 222 ? 137.652 106.233 155.731 1.00 109.15 ? 222  ILE A CG1 1 
ATOM   1698 C CG2 . ILE A 1 222 ? 140.086 106.774 155.900 1.00 114.04 ? 222  ILE A CG2 1 
ATOM   1699 C CD1 . ILE A 1 222 ? 136.211 106.683 155.795 1.00 103.17 ? 222  ILE A CD1 1 
ATOM   1700 N N   . VAL A 1 223 ? 140.049 109.729 157.763 1.00 89.61  ? 223  VAL A N   1 
ATOM   1701 C CA  . VAL A 1 223 ? 141.308 110.302 158.221 1.00 90.95  ? 223  VAL A CA  1 
ATOM   1702 C C   . VAL A 1 223 ? 141.082 111.014 159.545 1.00 94.64  ? 223  VAL A C   1 
ATOM   1703 O O   . VAL A 1 223 ? 141.695 110.668 160.561 1.00 104.66 ? 223  VAL A O   1 
ATOM   1704 C CB  . VAL A 1 223 ? 141.896 111.262 157.173 1.00 101.03 ? 223  VAL A CB  1 
ATOM   1705 C CG1 . VAL A 1 223 ? 143.350 111.566 157.494 1.00 102.91 ? 223  VAL A CG1 1 
ATOM   1706 C CG2 . VAL A 1 223 ? 141.763 110.670 155.782 1.00 103.84 ? 223  VAL A CG2 1 
ATOM   1707 N N   . TYR A 1 224 ? 140.201 112.013 159.546 1.00 95.72  ? 224  TYR A N   1 
ATOM   1708 C CA  . TYR A 1 224 ? 139.962 112.778 160.764 1.00 100.96 ? 224  TYR A CA  1 
ATOM   1709 C C   . TYR A 1 224 ? 139.301 111.916 161.831 1.00 107.55 ? 224  TYR A C   1 
ATOM   1710 O O   . TYR A 1 224 ? 139.763 111.863 162.978 1.00 108.90 ? 224  TYR A O   1 
ATOM   1711 C CB  . TYR A 1 224 ? 139.094 113.996 160.449 1.00 101.92 ? 224  TYR A CB  1 
ATOM   1712 C CG  . TYR A 1 224 ? 139.697 114.942 159.437 1.00 101.51 ? 224  TYR A CG  1 
ATOM   1713 C CD1 . TYR A 1 224 ? 141.070 115.009 159.246 1.00 100.77 ? 224  TYR A CD1 1 
ATOM   1714 C CD2 . TYR A 1 224 ? 138.891 115.770 158.671 1.00 104.18 ? 224  TYR A CD2 1 
ATOM   1715 C CE1 . TYR A 1 224 ? 141.620 115.871 158.321 1.00 100.74 ? 224  TYR A CE1 1 
ATOM   1716 C CE2 . TYR A 1 224 ? 139.432 116.635 157.745 1.00 105.25 ? 224  TYR A CE2 1 
ATOM   1717 C CZ  . TYR A 1 224 ? 140.796 116.682 157.574 1.00 102.84 ? 224  TYR A CZ  1 
ATOM   1718 O OH  . TYR A 1 224 ? 141.339 117.544 156.651 1.00 107.29 ? 224  TYR A OH  1 
ATOM   1719 N N   . THR A 1 225 ? 138.223 111.220 161.469 1.00 108.84 ? 225  THR A N   1 
ATOM   1720 C CA  . THR A 1 225 ? 137.476 110.458 162.462 1.00 107.58 ? 225  THR A CA  1 
ATOM   1721 C C   . THR A 1 225 ? 138.349 109.389 163.102 1.00 109.35 ? 225  THR A C   1 
ATOM   1722 O O   . THR A 1 225 ? 138.277 109.166 164.315 1.00 110.92 ? 225  THR A O   1 
ATOM   1723 C CB  . THR A 1 225 ? 136.241 109.827 161.823 1.00 106.62 ? 225  THR A CB  1 
ATOM   1724 O OG1 . THR A 1 225 ? 135.363 110.859 161.358 1.00 110.66 ? 225  THR A OG1 1 
ATOM   1725 C CG2 . THR A 1 225 ? 135.504 108.961 162.832 1.00 107.35 ? 225  THR A CG2 1 
ATOM   1726 N N   . LEU A 1 226 ? 139.173 108.709 162.304 1.00 102.38 ? 226  LEU A N   1 
ATOM   1727 C CA  . LEU A 1 226 ? 140.079 107.721 162.877 1.00 97.16  ? 226  LEU A CA  1 
ATOM   1728 C C   . LEU A 1 226 ? 141.114 108.383 163.774 1.00 105.21 ? 226  LEU A C   1 
ATOM   1729 O O   . LEU A 1 226 ? 141.318 107.953 164.913 1.00 112.04 ? 226  LEU A O   1 
ATOM   1730 C CB  . LEU A 1 226 ? 140.764 106.926 161.770 1.00 96.92  ? 226  LEU A CB  1 
ATOM   1731 C CG  . LEU A 1 226 ? 140.082 105.606 161.414 1.00 104.16 ? 226  LEU A CG  1 
ATOM   1732 C CD1 . LEU A 1 226 ? 138.677 105.852 160.893 1.00 105.49 ? 226  LEU A CD1 1 
ATOM   1733 C CD2 . LEU A 1 226 ? 140.904 104.834 160.398 1.00 109.93 ? 226  LEU A CD2 1 
ATOM   1734 N N   . LEU A 1 227 ? 141.762 109.447 163.298 1.00 95.75  ? 227  LEU A N   1 
ATOM   1735 C CA  . LEU A 1 227 ? 142.782 110.091 164.117 1.00 91.62  ? 227  LEU A CA  1 
ATOM   1736 C C   . LEU A 1 227 ? 142.198 110.626 165.417 1.00 94.84  ? 227  LEU A C   1 
ATOM   1737 O O   . LEU A 1 227 ? 142.942 110.877 166.371 1.00 95.53  ? 227  LEU A O   1 
ATOM   1738 C CB  . LEU A 1 227 ? 143.458 111.216 163.337 1.00 90.89  ? 227  LEU A CB  1 
ATOM   1739 C CG  . LEU A 1 227 ? 144.394 110.773 162.211 1.00 95.29  ? 227  LEU A CG  1 
ATOM   1740 C CD1 . LEU A 1 227 ? 144.939 111.977 161.465 1.00 96.77  ? 227  LEU A CD1 1 
ATOM   1741 C CD2 . LEU A 1 227 ? 145.532 109.927 162.756 1.00 94.62  ? 227  LEU A CD2 1 
ATOM   1742 N N   . LEU A 1 228 ? 140.879 110.809 165.475 1.00 100.47 ? 228  LEU A N   1 
ATOM   1743 C CA  . LEU A 1 228 ? 140.242 111.218 166.722 1.00 103.41 ? 228  LEU A CA  1 
ATOM   1744 C C   . LEU A 1 228 ? 139.919 110.013 167.599 1.00 106.09 ? 228  LEU A C   1 
ATOM   1745 O O   . LEU A 1 228 ? 140.272 109.976 168.783 1.00 107.98 ? 228  LEU A O   1 
ATOM   1746 C CB  . LEU A 1 228 ? 138.974 112.016 166.418 1.00 105.64 ? 228  LEU A CB  1 
ATOM   1747 C CG  . LEU A 1 228 ? 139.132 113.525 166.232 1.00 103.83 ? 228  LEU A CG  1 
ATOM   1748 C CD1 . LEU A 1 228 ? 140.344 113.880 165.392 1.00 103.91 ? 228  LEU A CD1 1 
ATOM   1749 C CD2 . LEU A 1 228 ? 137.877 114.092 165.599 1.00 108.99 ? 228  LEU A CD2 1 
ATOM   1750 N N   . ARG A 1 229 ? 139.244 109.015 167.031 1.00 115.68 ? 229  ARG A N   1 
ATOM   1751 C CA  . ARG A 1 229 ? 138.700 107.921 167.827 1.00 120.02 ? 229  ARG A CA  1 
ATOM   1752 C C   . ARG A 1 229 ? 139.773 106.926 168.253 1.00 121.58 ? 229  ARG A C   1 
ATOM   1753 O O   . ARG A 1 229 ? 139.731 106.411 169.375 1.00 120.24 ? 229  ARG A O   1 
ATOM   1754 C CB  . ARG A 1 229 ? 137.606 107.210 167.031 1.00 122.67 ? 229  ARG A CB  1 
ATOM   1755 C CG  . ARG A 1 229 ? 136.686 106.327 167.852 1.00 120.11 ? 229  ARG A CG  1 
ATOM   1756 C CD  . ARG A 1 229 ? 135.643 105.674 166.959 1.00 122.51 ? 229  ARG A CD  1 
ATOM   1757 N NE  . ARG A 1 229 ? 134.584 105.017 167.716 1.00 125.58 ? 229  ARG A NE  1 
ATOM   1758 C CZ  . ARG A 1 229 ? 133.516 104.452 167.171 1.00 125.62 ? 229  ARG A CZ  1 
ATOM   1759 N NH1 . ARG A 1 229 ? 133.327 104.449 165.861 1.00 120.55 ? 229  ARG A NH1 1 
ATOM   1760 N NH2 . ARG A 1 229 ? 132.611 103.879 167.959 1.00 121.56 ? 229  ARG A NH2 1 
ATOM   1761 N N   . PHE A 1 230 ? 140.735 106.642 167.379 1.00 109.90 ? 230  PHE A N   1 
ATOM   1762 C CA  . PHE A 1 230 ? 141.732 105.604 167.596 1.00 105.75 ? 230  PHE A CA  1 
ATOM   1763 C C   . PHE A 1 230 ? 142.999 106.137 168.253 1.00 107.83 ? 230  PHE A C   1 
ATOM   1764 O O   . PHE A 1 230 ? 143.585 105.462 169.104 1.00 115.02 ? 230  PHE A O   1 
ATOM   1765 C CB  . PHE A 1 230 ? 142.076 104.951 166.251 1.00 107.21 ? 230  PHE A CB  1 
ATOM   1766 C CG  . PHE A 1 230 ? 142.581 103.543 166.365 1.00 116.51 ? 230  PHE A CG  1 
ATOM   1767 C CD1 . PHE A 1 230 ? 141.776 102.542 166.881 1.00 120.03 ? 230  PHE A CD1 1 
ATOM   1768 C CD2 . PHE A 1 230 ? 143.857 103.218 165.939 1.00 115.64 ? 230  PHE A CD2 1 
ATOM   1769 C CE1 . PHE A 1 230 ? 142.240 101.245 166.979 1.00 115.56 ? 230  PHE A CE1 1 
ATOM   1770 C CE2 . PHE A 1 230 ? 144.326 101.922 166.035 1.00 115.20 ? 230  PHE A CE2 1 
ATOM   1771 C CZ  . PHE A 1 230 ? 143.516 100.935 166.555 1.00 112.77 ? 230  PHE A CZ  1 
ATOM   1772 N N   . LEU A 1 231 ? 143.435 107.339 167.876 1.00 92.41  ? 231  LEU A N   1 
ATOM   1773 C CA  . LEU A 1 231 ? 144.694 107.870 168.386 1.00 98.21  ? 231  LEU A CA  1 
ATOM   1774 C C   . LEU A 1 231 ? 144.474 108.742 169.618 1.00 100.19 ? 231  LEU A C   1 
ATOM   1775 O O   . LEU A 1 231 ? 145.009 108.461 170.695 1.00 105.16 ? 231  LEU A O   1 
ATOM   1776 C CB  . LEU A 1 231 ? 145.407 108.665 167.288 1.00 96.80  ? 231  LEU A CB  1 
ATOM   1777 C CG  . LEU A 1 231 ? 146.678 109.409 167.707 1.00 94.85  ? 231  LEU A CG  1 
ATOM   1778 C CD1 . LEU A 1 231 ? 147.742 108.430 168.170 1.00 100.69 ? 231  LEU A CD1 1 
ATOM   1779 C CD2 . LEU A 1 231 ? 147.199 110.260 166.562 1.00 94.26  ? 231  LEU A CD2 1 
ATOM   1780 N N   . CYS A 1 232 ? 143.684 109.806 169.477 1.00 106.69 ? 232  CYS A N   1 
ATOM   1781 C CA  . CYS A 1 232 ? 143.520 110.767 170.559 1.00 109.01 ? 232  CYS A CA  1 
ATOM   1782 C C   . CYS A 1 232 ? 142.493 110.329 171.594 1.00 112.44 ? 232  CYS A C   1 
ATOM   1783 O O   . CYS A 1 232 ? 142.344 111.002 172.618 1.00 111.93 ? 232  CYS A O   1 
ATOM   1784 C CB  . CYS A 1 232 ? 143.119 112.127 169.989 1.00 110.48 ? 232  CYS A CB  1 
ATOM   1785 S SG  . CYS A 1 232 ? 144.330 112.826 168.850 1.00 117.66 ? 232  CYS A SG  1 
ATOM   1786 N N   . LYS A 1 233 ? 141.788 109.224 171.357 1.00 116.61 ? 233  LYS A N   1 
ATOM   1787 C CA  . LYS A 1 233 ? 140.754 108.751 172.277 1.00 113.80 ? 233  LYS A CA  1 
ATOM   1788 C C   . LYS A 1 233 ? 139.720 109.840 172.545 1.00 110.58 ? 233  LYS A C   1 
ATOM   1789 O O   . LYS A 1 233 ? 139.291 110.051 173.681 1.00 111.86 ? 233  LYS A O   1 
ATOM   1790 C CB  . LYS A 1 233 ? 141.367 108.254 173.589 1.00 116.21 ? 233  LYS A CB  1 
ATOM   1791 C CG  . LYS A 1 233 ? 142.470 107.220 173.415 1.00 117.93 ? 233  LYS A CG  1 
ATOM   1792 C CD  . LYS A 1 233 ? 141.895 105.818 173.278 1.00 120.64 ? 233  LYS A CD  1 
ATOM   1793 C CE  . LYS A 1 233 ? 142.676 104.983 172.275 1.00 120.26 ? 233  LYS A CE  1 
ATOM   1794 N NZ  . LYS A 1 233 ? 141.948 103.741 171.894 1.00 117.98 ? 233  LYS A NZ  1 
ATOM   1795 N N   . ILE A 1 234 ? 139.318 110.540 171.489 1.00 110.45 ? 234  ILE A N   1 
ATOM   1796 C CA  . ILE A 1 234 ? 138.306 111.587 171.559 1.00 111.79 ? 234  ILE A CA  1 
ATOM   1797 C C   . ILE A 1 234 ? 137.082 111.107 170.795 1.00 113.89 ? 234  ILE A C   1 
ATOM   1798 O O   . ILE A 1 234 ? 137.193 110.674 169.642 1.00 115.05 ? 234  ILE A O   1 
ATOM   1799 C CB  . ILE A 1 234 ? 138.826 112.915 170.983 1.00 113.49 ? 234  ILE A CB  1 
ATOM   1800 C CG1 . ILE A 1 234 ? 140.053 113.391 171.763 1.00 116.76 ? 234  ILE A CG1 1 
ATOM   1801 C CG2 . ILE A 1 234 ? 137.734 113.973 171.022 1.00 110.19 ? 234  ILE A CG2 1 
ATOM   1802 C CD1 . ILE A 1 234 ? 140.856 114.456 171.046 1.00 115.64 ? 234  ILE A CD1 1 
ATOM   1803 N N   . ASN A 1 235 ? 135.923 111.181 171.430 1.00 110.05 ? 235  ASN A N   1 
ATOM   1804 C CA  . ASN A 1 235 ? 134.693 110.731 170.795 1.00 111.67 ? 235  ASN A CA  1 
ATOM   1805 C C   . ASN A 1 235 ? 134.375 111.630 169.607 1.00 113.10 ? 235  ASN A C   1 
ATOM   1806 O O   . ASN A 1 235 ? 133.974 112.783 169.813 1.00 111.58 ? 235  ASN A O   1 
ATOM   1807 C CB  . ASN A 1 235 ? 133.545 110.745 171.797 1.00 110.02 ? 235  ASN A CB  1 
ATOM   1808 C CG  . ASN A 1 235 ? 132.283 110.118 171.244 1.00 112.84 ? 235  ASN A CG  1 
ATOM   1809 O OD1 . ASN A 1 235 ? 132.251 109.669 170.098 1.00 108.24 ? 235  ASN A OD1 1 
ATOM   1810 N ND2 . ASN A 1 235 ? 131.236 110.080 172.058 1.00 114.67 ? 235  ASN A ND2 1 
ATOM   1811 N N   . PRO A 1 236 ? 134.524 111.162 168.365 1.00 115.15 ? 236  PRO A N   1 
ATOM   1812 C CA  . PRO A 1 236 ? 134.371 112.077 167.223 1.00 114.03 ? 236  PRO A CA  1 
ATOM   1813 C C   . PRO A 1 236 ? 133.002 112.722 167.135 1.00 109.89 ? 236  PRO A C   1 
ATOM   1814 O O   . PRO A 1 236 ? 132.891 113.853 166.648 1.00 108.50 ? 236  PRO A O   1 
ATOM   1815 C CB  . PRO A 1 236 ? 134.646 111.173 166.014 1.00 116.80 ? 236  PRO A CB  1 
ATOM   1816 C CG  . PRO A 1 236 ? 134.336 109.802 166.488 1.00 116.37 ? 236  PRO A CG  1 
ATOM   1817 C CD  . PRO A 1 236 ? 134.736 109.772 167.930 1.00 114.32 ? 236  PRO A CD  1 
ATOM   1818 N N   . LEU A 1 237 ? 131.949 112.035 167.578 1.00 114.32 ? 237  LEU A N   1 
ATOM   1819 C CA  . LEU A 1 237 ? 130.610 112.594 167.463 1.00 114.88 ? 237  LEU A CA  1 
ATOM   1820 C C   . LEU A 1 237 ? 130.425 113.825 168.337 1.00 115.71 ? 237  LEU A C   1 
ATOM   1821 O O   . LEU A 1 237 ? 129.687 114.737 167.951 1.00 119.72 ? 237  LEU A O   1 
ATOM   1822 C CB  . LEU A 1 237 ? 129.570 111.530 167.814 1.00 117.89 ? 237  LEU A CB  1 
ATOM   1823 C CG  . LEU A 1 237 ? 129.748 110.205 167.066 1.00 120.86 ? 237  LEU A CG  1 
ATOM   1824 C CD1 . LEU A 1 237 ? 128.671 109.207 167.458 1.00 121.44 ? 237  LEU A CD1 1 
ATOM   1825 C CD2 . LEU A 1 237 ? 129.752 110.432 165.560 1.00 117.67 ? 237  LEU A CD2 1 
ATOM   1826 N N   . ARG A 1 238 ? 131.072 113.875 169.502 1.00 111.74 ? 238  ARG A N   1 
ATOM   1827 C CA  . ARG A 1 238 ? 131.060 115.098 170.297 1.00 114.23 ? 238  ARG A CA  1 
ATOM   1828 C C   . ARG A 1 238 ? 131.984 116.148 169.696 1.00 115.34 ? 238  ARG A C   1 
ATOM   1829 O O   . ARG A 1 238 ? 131.693 117.348 169.755 1.00 119.04 ? 238  ARG A O   1 
ATOM   1830 C CB  . ARG A 1 238 ? 131.473 114.796 171.737 1.00 115.08 ? 238  ARG A CB  1 
ATOM   1831 C CG  . ARG A 1 238 ? 130.841 113.541 172.318 1.00 117.57 ? 238  ARG A CG  1 
ATOM   1832 C CD  . ARG A 1 238 ? 130.744 113.612 173.835 1.00 117.66 ? 238  ARG A CD  1 
ATOM   1833 N NE  . ARG A 1 238 ? 131.844 114.367 174.425 1.00 121.39 ? 238  ARG A NE  1 
ATOM   1834 C CZ  . ARG A 1 238 ? 133.041 113.865 174.698 1.00 121.28 ? 238  ARG A CZ  1 
ATOM   1835 N NH1 . ARG A 1 238 ? 133.337 112.601 174.444 1.00 121.87 ? 238  ARG A NH1 1 
ATOM   1836 N NH2 . ARG A 1 238 ? 133.966 114.653 175.240 1.00 118.07 ? 238  ARG A NH2 1 
ATOM   1837 N N   . PHE A 1 239 ? 133.100 115.710 169.115 1.00 104.00 ? 239  PHE A N   1 
ATOM   1838 C CA  . PHE A 1 239 ? 134.041 116.641 168.505 1.00 107.10 ? 239  PHE A CA  1 
ATOM   1839 C C   . PHE A 1 239 ? 133.369 117.437 167.393 1.00 107.28 ? 239  PHE A C   1 
ATOM   1840 O O   . PHE A 1 239 ? 133.426 118.673 167.368 1.00 108.13 ? 239  PHE A O   1 
ATOM   1841 C CB  . PHE A 1 239 ? 135.239 115.862 167.967 1.00 104.02 ? 239  PHE A CB  1 
ATOM   1842 C CG  . PHE A 1 239 ? 136.364 116.722 167.491 1.00 100.54 ? 239  PHE A CG  1 
ATOM   1843 C CD1 . PHE A 1 239 ? 136.561 116.947 166.143 1.00 104.21 ? 239  PHE A CD1 1 
ATOM   1844 C CD2 . PHE A 1 239 ? 137.246 117.285 168.394 1.00 102.65 ? 239  PHE A CD2 1 
ATOM   1845 C CE1 . PHE A 1 239 ? 137.608 117.726 165.705 1.00 104.20 ? 239  PHE A CE1 1 
ATOM   1846 C CE2 . PHE A 1 239 ? 138.292 118.066 167.962 1.00 106.90 ? 239  PHE A CE2 1 
ATOM   1847 C CZ  . PHE A 1 239 ? 138.474 118.289 166.616 1.00 102.21 ? 239  PHE A CZ  1 
ATOM   1848 N N   . PHE A 1 240 ? 132.710 116.740 166.468 1.00 105.61 ? 240  PHE A N   1 
ATOM   1849 C CA  . PHE A 1 240 ? 132.037 117.426 165.371 1.00 103.97 ? 240  PHE A CA  1 
ATOM   1850 C C   . PHE A 1 240 ? 130.850 118.235 165.875 1.00 104.18 ? 240  PHE A C   1 
ATOM   1851 O O   . PHE A 1 240 ? 130.520 119.278 165.304 1.00 109.89 ? 240  PHE A O   1 
ATOM   1852 C CB  . PHE A 1 240 ? 131.596 116.417 164.313 1.00 104.84 ? 240  PHE A CB  1 
ATOM   1853 C CG  . PHE A 1 240 ? 132.736 115.809 163.548 1.00 107.62 ? 240  PHE A CG  1 
ATOM   1854 C CD1 . PHE A 1 240 ? 133.605 116.607 162.826 1.00 103.32 ? 240  PHE A CD1 1 
ATOM   1855 C CD2 . PHE A 1 240 ? 132.939 114.442 163.553 1.00 109.61 ? 240  PHE A CD2 1 
ATOM   1856 C CE1 . PHE A 1 240 ? 134.655 116.052 162.124 1.00 101.23 ? 240  PHE A CE1 1 
ATOM   1857 C CE2 . PHE A 1 240 ? 133.987 113.882 162.852 1.00 105.63 ? 240  PHE A CE2 1 
ATOM   1858 C CZ  . PHE A 1 240 ? 134.845 114.688 162.137 1.00 103.27 ? 240  PHE A CZ  1 
ATOM   1859 N N   . LYS A 1 241 ? 130.194 117.774 166.940 1.00 106.62 ? 241  LYS A N   1 
ATOM   1860 C CA  . LYS A 1 241 ? 129.115 118.563 167.521 1.00 104.20 ? 241  LYS A CA  1 
ATOM   1861 C C   . LYS A 1 241 ? 129.634 119.905 168.018 1.00 102.75 ? 241  LYS A C   1 
ATOM   1862 O O   . LYS A 1 241 ? 128.995 120.942 167.813 1.00 106.07 ? 241  LYS A O   1 
ATOM   1863 C CB  . LYS A 1 241 ? 128.449 117.792 168.659 1.00 99.70  ? 241  LYS A CB  1 
ATOM   1864 C CG  . LYS A 1 241 ? 127.267 116.940 168.225 1.00 104.40 ? 241  LYS A CG  1 
ATOM   1865 C CD  . LYS A 1 241 ? 126.066 117.799 167.856 1.00 108.32 ? 241  LYS A CD  1 
ATOM   1866 C CE  . LYS A 1 241 ? 124.805 116.963 167.706 1.00 108.63 ? 241  LYS A CE  1 
ATOM   1867 N NZ  . LYS A 1 241 ? 124.216 116.596 169.023 1.00 103.99 ? 241  LYS A NZ  1 
ATOM   1868 N N   . LYS A 1 242 ? 130.794 119.903 168.676 1.00 102.25 ? 242  LYS A N   1 
ATOM   1869 C CA  . LYS A 1 242 ? 131.371 121.159 169.145 1.00 104.64 ? 242  LYS A CA  1 
ATOM   1870 C C   . LYS A 1 242 ? 131.879 122.004 167.983 1.00 102.72 ? 242  LYS A C   1 
ATOM   1871 O O   . LYS A 1 242 ? 131.860 123.238 168.052 1.00 104.10 ? 242  LYS A O   1 
ATOM   1872 C CB  . LYS A 1 242 ? 132.502 120.886 170.138 1.00 103.52 ? 242  LYS A CB  1 
ATOM   1873 C CG  . LYS A 1 242 ? 132.097 120.113 171.390 1.00 108.64 ? 242  LYS A CG  1 
ATOM   1874 C CD  . LYS A 1 242 ? 130.808 120.630 172.021 1.00 109.30 ? 242  LYS A CD  1 
ATOM   1875 C CE  . LYS A 1 242 ? 130.892 122.111 172.358 1.00 102.15 ? 242  LYS A CE  1 
ATOM   1876 N NZ  . LYS A 1 242 ? 129.670 122.585 173.064 1.00 102.04 ? 242  LYS A NZ  1 
ATOM   1877 N N   . ILE A 1 243 ? 132.344 121.360 166.910 1.00 101.35 ? 243  ILE A N   1 
ATOM   1878 C CA  . ILE A 1 243 ? 132.934 122.105 165.802 1.00 100.04 ? 243  ILE A CA  1 
ATOM   1879 C C   . ILE A 1 243 ? 131.882 122.639 164.835 1.00 107.66 ? 243  ILE A C   1 
ATOM   1880 O O   . ILE A 1 243 ? 132.178 123.546 164.048 1.00 115.43 ? 243  ILE A O   1 
ATOM   1881 C CB  . ILE A 1 243 ? 133.953 121.208 165.072 1.00 101.65 ? 243  ILE A CB  1 
ATOM   1882 C CG1 . ILE A 1 243 ? 135.314 121.323 165.755 1.00 105.80 ? 243  ILE A CG1 1 
ATOM   1883 C CG2 . ILE A 1 243 ? 134.055 121.568 163.584 1.00 96.68  ? 243  ILE A CG2 1 
ATOM   1884 C CD1 . ILE A 1 243 ? 136.428 120.617 165.030 1.00 108.32 ? 243  ILE A CD1 1 
ATOM   1885 N N   . LYS A 1 244 ? 130.656 122.120 164.890 1.00 102.06 ? 244  LYS A N   1 
ATOM   1886 C CA  . LYS A 1 244 ? 129.651 122.337 163.853 1.00 95.15  ? 244  LYS A CA  1 
ATOM   1887 C C   . LYS A 1 244 ? 129.636 123.755 163.295 1.00 99.35  ? 244  LYS A C   1 
ATOM   1888 O O   . LYS A 1 244 ? 129.585 123.938 162.076 1.00 106.67 ? 244  LYS A O   1 
ATOM   1889 C CB  . LYS A 1 244 ? 128.265 121.986 164.394 1.00 96.54  ? 244  LYS A CB  1 
ATOM   1890 C CG  . LYS A 1 244 ? 127.846 122.790 165.609 1.00 102.63 ? 244  LYS A CG  1 
ATOM   1891 C CD  . LYS A 1 244 ? 126.681 122.130 166.325 1.00 103.76 ? 244  LYS A CD  1 
ATOM   1892 C CE  . LYS A 1 244 ? 126.253 122.922 167.547 1.00 100.97 ? 244  LYS A CE  1 
ATOM   1893 N NZ  . LYS A 1 244 ? 125.096 122.291 168.238 1.00 99.65  ? 244  LYS A NZ  1 
ATOM   1894 N N   . GLU A 1 245 ? 129.682 124.765 164.166 1.00 95.58  ? 245  GLU A N   1 
ATOM   1895 C CA  . GLU A 1 245 ? 129.560 126.141 163.692 1.00 88.74  ? 245  GLU A CA  1 
ATOM   1896 C C   . GLU A 1 245 ? 130.631 126.470 162.660 1.00 96.01  ? 245  GLU A C   1 
ATOM   1897 O O   . GLU A 1 245 ? 130.330 127.032 161.599 1.00 100.07 ? 245  GLU A O   1 
ATOM   1898 C CB  . GLU A 1 245 ? 129.643 127.112 164.868 1.00 85.46  ? 245  GLU A CB  1 
ATOM   1899 C CG  . GLU A 1 245 ? 128.530 128.141 164.888 1.00 97.70  ? 245  GLU A CG  1 
ATOM   1900 C CD  . GLU A 1 245 ? 128.677 129.132 166.023 1.00 104.04 ? 245  GLU A CD  1 
ATOM   1901 O OE1 . GLU A 1 245 ? 129.257 128.762 167.065 1.00 99.35  ? 245  GLU A OE1 1 
ATOM   1902 O OE2 . GLU A 1 245 ? 128.213 130.282 165.874 1.00 107.30 ? 245  GLU A OE2 1 
ATOM   1903 N N   . ALA A 1 246 ? 131.886 126.124 162.948 1.00 104.22 ? 246  ALA A N   1 
ATOM   1904 C CA  . ALA A 1 246 ? 132.959 126.411 162.005 1.00 102.99 ? 246  ALA A CA  1 
ATOM   1905 C C   . ALA A 1 246 ? 132.745 125.694 160.681 1.00 99.19  ? 246  ALA A C   1 
ATOM   1906 O O   . ALA A 1 246 ? 132.951 126.288 159.617 1.00 101.06 ? 246  ALA A O   1 
ATOM   1907 C CB  . ALA A 1 246 ? 134.307 126.018 162.604 1.00 100.12 ? 246  ALA A CB  1 
ATOM   1908 N N   . MET A 1 247 ? 132.335 124.427 160.723 1.00 94.31  ? 247  MET A N   1 
ATOM   1909 C CA  . MET A 1 247 ? 132.115 123.684 159.488 1.00 90.70  ? 247  MET A CA  1 
ATOM   1910 C C   . MET A 1 247 ? 131.035 124.344 158.641 1.00 99.58  ? 247  MET A C   1 
ATOM   1911 O O   . MET A 1 247 ? 131.202 124.518 157.430 1.00 106.87 ? 247  MET A O   1 
ATOM   1912 C CB  . MET A 1 247 ? 131.735 122.240 159.810 1.00 98.48  ? 247  MET A CB  1 
ATOM   1913 C CG  . MET A 1 247 ? 132.927 121.319 160.015 1.00 102.05 ? 247  MET A CG  1 
ATOM   1914 S SD  . MET A 1 247 ? 132.547 119.550 160.069 1.00 122.67 ? 247  MET A SD  1 
ATOM   1915 C CE  . MET A 1 247 ? 130.759 119.519 159.950 1.00 106.55 ? 247  MET A CE  1 
ATOM   1916 N N   . LEU A 1 248 ? 129.918 124.722 159.265 1.00 96.35  ? 248  LEU A N   1 
ATOM   1917 C CA  . LEU A 1 248 ? 128.828 125.338 158.516 1.00 86.96  ? 248  LEU A CA  1 
ATOM   1918 C C   . LEU A 1 248 ? 129.240 126.686 157.944 1.00 89.18  ? 248  LEU A C   1 
ATOM   1919 O O   . LEU A 1 248 ? 128.922 127.002 156.790 1.00 98.08  ? 248  LEU A O   1 
ATOM   1920 C CB  . LEU A 1 248 ? 127.603 125.491 159.414 1.00 85.09  ? 248  LEU A CB  1 
ATOM   1921 C CG  . LEU A 1 248 ? 126.353 126.066 158.750 1.00 85.36  ? 248  LEU A CG  1 
ATOM   1922 C CD1 . LEU A 1 248 ? 125.995 125.291 157.497 1.00 91.54  ? 248  LEU A CD1 1 
ATOM   1923 C CD2 . LEU A 1 248 ? 125.196 126.060 159.728 1.00 94.55  ? 248  LEU A CD2 1 
ATOM   1924 N N   . VAL A 1 249 ? 129.942 127.500 158.735 1.00 84.67  ? 249  VAL A N   1 
ATOM   1925 C CA  . VAL A 1 249 ? 130.372 128.802 158.239 1.00 84.13  ? 249  VAL A CA  1 
ATOM   1926 C C   . VAL A 1 249 ? 131.327 128.633 157.067 1.00 91.27  ? 249  VAL A C   1 
ATOM   1927 O O   . VAL A 1 249 ? 131.239 129.356 156.070 1.00 90.64  ? 249  VAL A O   1 
ATOM   1928 C CB  . VAL A 1 249 ? 131.009 129.623 159.372 1.00 85.59  ? 249  VAL A CB  1 
ATOM   1929 C CG1 . VAL A 1 249 ? 131.734 130.830 158.801 1.00 91.10  ? 249  VAL A CG1 1 
ATOM   1930 C CG2 . VAL A 1 249 ? 129.946 130.052 160.370 1.00 92.01  ? 249  VAL A CG2 1 
ATOM   1931 N N   . ALA A 1 250 ? 132.259 127.683 157.166 1.00 100.25 ? 250  ALA A N   1 
ATOM   1932 C CA  . ALA A 1 250 ? 133.187 127.440 156.067 1.00 98.18  ? 250  ALA A CA  1 
ATOM   1933 C C   . ALA A 1 250 ? 132.448 126.962 154.825 1.00 98.72  ? 250  ALA A C   1 
ATOM   1934 O O   . ALA A 1 250 ? 132.743 127.394 153.705 1.00 103.93 ? 250  ALA A O   1 
ATOM   1935 C CB  . ALA A 1 250 ? 134.239 126.419 156.495 1.00 102.70 ? 250  ALA A CB  1 
ATOM   1936 N N   . PHE A 1 251 ? 131.479 126.064 155.005 1.00 89.35  ? 251  PHE A N   1 
ATOM   1937 C CA  . PHE A 1 251 ? 130.719 125.551 153.872 1.00 85.15  ? 251  PHE A CA  1 
ATOM   1938 C C   . PHE A 1 251 ? 129.967 126.672 153.169 1.00 87.98  ? 251  PHE A C   1 
ATOM   1939 O O   . PHE A 1 251 ? 129.937 126.739 151.936 1.00 91.36  ? 251  PHE A O   1 
ATOM   1940 C CB  . PHE A 1 251 ? 129.754 124.466 154.349 1.00 83.91  ? 251  PHE A CB  1 
ATOM   1941 C CG  . PHE A 1 251 ? 129.003 123.789 153.242 1.00 82.79  ? 251  PHE A CG  1 
ATOM   1942 C CD1 . PHE A 1 251 ? 127.862 124.361 152.709 1.00 86.84  ? 251  PHE A CD1 1 
ATOM   1943 C CD2 . PHE A 1 251 ? 129.434 122.577 152.737 1.00 90.76  ? 251  PHE A CD2 1 
ATOM   1944 C CE1 . PHE A 1 251 ? 127.169 123.738 151.694 1.00 93.04  ? 251  PHE A CE1 1 
ATOM   1945 C CE2 . PHE A 1 251 ? 128.744 121.950 151.720 1.00 91.40  ? 251  PHE A CE2 1 
ATOM   1946 C CZ  . PHE A 1 251 ? 127.611 122.532 151.199 1.00 91.36  ? 251  PHE A CZ  1 
ATOM   1947 N N   . SER A 1 252 ? 129.347 127.565 153.942 1.00 89.02  ? 252  SER A N   1 
ATOM   1948 C CA  . SER A 1 252 ? 128.564 128.635 153.333 1.00 86.27  ? 252  SER A CA  1 
ATOM   1949 C C   . SER A 1 252 ? 129.458 129.694 152.701 1.00 92.64  ? 252  SER A C   1 
ATOM   1950 O O   . SER A 1 252 ? 129.135 130.231 151.635 1.00 86.92  ? 252  SER A O   1 
ATOM   1951 C CB  . SER A 1 252 ? 127.647 129.268 154.377 1.00 91.82  ? 252  SER A CB  1 
ATOM   1952 O OG  . SER A 1 252 ? 126.921 128.277 155.080 1.00 100.92 ? 252  SER A OG  1 
ATOM   1953 N N   . THR A 1 253 ? 130.590 130.004 153.334 1.00 99.66  ? 253  THR A N   1 
ATOM   1954 C CA  . THR A 1 253 ? 131.399 131.140 152.908 1.00 91.47  ? 253  THR A CA  1 
ATOM   1955 C C   . THR A 1 253 ? 132.394 130.774 151.816 1.00 87.86  ? 253  THR A C   1 
ATOM   1956 O O   . THR A 1 253 ? 132.717 131.619 150.976 1.00 90.36  ? 253  THR A O   1 
ATOM   1957 C CB  . THR A 1 253 ? 132.150 131.722 154.104 1.00 86.20  ? 253  THR A CB  1 
ATOM   1958 O OG1 . THR A 1 253 ? 131.259 131.844 155.219 1.00 90.94  ? 253  THR A OG1 1 
ATOM   1959 C CG2 . THR A 1 253 ? 132.714 133.085 153.766 1.00 87.67  ? 253  THR A CG2 1 
ATOM   1960 N N   . CYS A 1 254 ? 132.890 129.540 151.807 1.00 98.20  ? 254  CYS A N   1 
ATOM   1961 C CA  . CYS A 1 254 ? 133.921 129.110 150.867 1.00 96.56  ? 254  CYS A CA  1 
ATOM   1962 C C   . CYS A 1 254 ? 135.197 129.930 151.003 1.00 99.30  ? 254  CYS A C   1 
ATOM   1963 O O   . CYS A 1 254 ? 135.870 130.205 150.006 1.00 103.24 ? 254  CYS A O   1 
ATOM   1964 C CB  . CYS A 1 254 ? 133.415 129.175 149.423 1.00 95.39  ? 254  CYS A CB  1 
ATOM   1965 S SG  . CYS A 1 254 ? 131.876 128.283 149.135 1.00 118.34 ? 254  CYS A SG  1 
ATOM   1966 N N   . SER A 1 255 ? 135.544 130.335 152.223 1.00 95.56  ? 255  SER A N   1 
ATOM   1967 C CA  . SER A 1 255 ? 136.739 131.130 152.480 1.00 96.97  ? 255  SER A CA  1 
ATOM   1968 C C   . SER A 1 255 ? 137.329 130.712 153.817 1.00 98.17  ? 255  SER A C   1 
ATOM   1969 O O   . SER A 1 255 ? 136.773 131.036 154.871 1.00 105.71 ? 255  SER A O   1 
ATOM   1970 C CB  . SER A 1 255 ? 136.414 132.624 152.487 1.00 102.47 ? 255  SER A CB  1 
ATOM   1971 O OG  . SER A 1 255 ? 137.533 133.384 152.907 1.00 96.76  ? 255  SER A OG  1 
ATOM   1972 N N   . SER A 1 256 ? 138.456 129.999 153.774 1.00 91.64  ? 256  SER A N   1 
ATOM   1973 C CA  . SER A 1 256 ? 139.105 129.576 155.010 1.00 89.88  ? 256  SER A CA  1 
ATOM   1974 C C   . SER A 1 256 ? 139.613 130.776 155.798 1.00 96.23  ? 256  SER A C   1 
ATOM   1975 O O   . SER A 1 256 ? 139.447 130.848 157.021 1.00 96.91  ? 256  SER A O   1 
ATOM   1976 C CB  . SER A 1 256 ? 140.251 128.617 154.697 1.00 97.45  ? 256  SER A CB  1 
ATOM   1977 O OG  . SER A 1 256 ? 141.268 128.714 155.677 1.00 93.74  ? 256  SER A OG  1 
ATOM   1978 N N   . ALA A 1 257 ? 140.240 131.733 155.111 1.00 99.60  ? 257  ALA A N   1 
ATOM   1979 C CA  . ALA A 1 257 ? 140.764 132.909 155.796 1.00 94.30  ? 257  ALA A CA  1 
ATOM   1980 C C   . ALA A 1 257 ? 139.641 133.705 156.446 1.00 94.75  ? 257  ALA A C   1 
ATOM   1981 O O   . ALA A 1 257 ? 139.749 134.124 157.604 1.00 92.28  ? 257  ALA A O   1 
ATOM   1982 C CB  . ALA A 1 257 ? 141.545 133.782 154.815 1.00 89.69  ? 257  ALA A CB  1 
ATOM   1983 N N   . ALA A 1 258 ? 138.547 133.920 155.715 1.00 97.67  ? 258  ALA A N   1 
ATOM   1984 C CA  . ALA A 1 258 ? 137.407 134.626 156.285 1.00 94.44  ? 258  ALA A CA  1 
ATOM   1985 C C   . ALA A 1 258 ? 136.730 133.824 157.385 1.00 95.28  ? 258  ALA A C   1 
ATOM   1986 O O   . ALA A 1 258 ? 136.123 134.417 158.282 1.00 101.53 ? 258  ALA A O   1 
ATOM   1987 C CB  . ALA A 1 258 ? 136.395 134.961 155.191 1.00 89.17  ? 258  ALA A CB  1 
ATOM   1988 N N   . THR A 1 259 ? 136.812 132.496 157.335 1.00 92.19  ? 259  THR A N   1 
ATOM   1989 C CA  . THR A 1 259 ? 136.240 131.652 158.374 1.00 91.20  ? 259  THR A CA  1 
ATOM   1990 C C   . THR A 1 259 ? 137.136 131.534 159.597 1.00 92.22  ? 259  THR A C   1 
ATOM   1991 O O   . THR A 1 259 ? 136.673 131.057 160.639 1.00 93.76  ? 259  THR A O   1 
ATOM   1992 C CB  . THR A 1 259 ? 135.964 130.255 157.816 1.00 96.24  ? 259  THR A CB  1 
ATOM   1993 O OG1 . THR A 1 259 ? 135.128 130.357 156.658 1.00 108.04 ? 259  THR A OG1 1 
ATOM   1994 C CG2 . THR A 1 259 ? 135.282 129.386 158.858 1.00 90.75  ? 259  THR A CG2 1 
ATOM   1995 N N   . LEU A 1 260 ? 138.393 131.960 159.499 1.00 96.83  ? 260  LEU A N   1 
ATOM   1996 C CA  . LEU A 1 260 ? 139.318 131.780 160.614 1.00 98.36  ? 260  LEU A CA  1 
ATOM   1997 C C   . LEU A 1 260 ? 138.783 132.321 161.933 1.00 94.30  ? 260  LEU A C   1 
ATOM   1998 O O   . LEU A 1 260 ? 138.906 131.615 162.948 1.00 98.19  ? 260  LEU A O   1 
ATOM   1999 C CB  . LEU A 1 260 ? 140.663 132.431 160.272 1.00 97.17  ? 260  LEU A CB  1 
ATOM   2000 C CG  . LEU A 1 260 ? 141.741 132.339 161.351 1.00 89.14  ? 260  LEU A CG  1 
ATOM   2001 C CD1 . LEU A 1 260 ? 141.995 130.895 161.736 1.00 98.39  ? 260  LEU A CD1 1 
ATOM   2002 C CD2 . LEU A 1 260 ? 143.019 132.994 160.870 1.00 88.95  ? 260  LEU A CD2 1 
ATOM   2003 N N   . PRO A 1 261 ? 138.200 133.521 162.005 1.00 81.94  ? 261  PRO A N   1 
ATOM   2004 C CA  . PRO A 1 261 ? 137.716 134.001 163.310 1.00 85.44  ? 261  PRO A CA  1 
ATOM   2005 C C   . PRO A 1 261 ? 136.744 133.044 163.973 1.00 92.32  ? 261  PRO A C   1 
ATOM   2006 O O   . PRO A 1 261 ? 136.831 132.816 165.186 1.00 97.39  ? 261  PRO A O   1 
ATOM   2007 C CB  . PRO A 1 261 ? 137.053 135.340 162.962 1.00 79.84  ? 261  PRO A CB  1 
ATOM   2008 C CG  . PRO A 1 261 ? 137.703 135.768 161.699 1.00 82.76  ? 261  PRO A CG  1 
ATOM   2009 C CD  . PRO A 1 261 ? 137.967 134.509 160.939 1.00 75.75  ? 261  PRO A CD  1 
ATOM   2010 N N   . VAL A 1 262 ? 135.826 132.458 163.204 1.00 95.24  ? 262  VAL A N   1 
ATOM   2011 C CA  . VAL A 1 262 ? 134.903 131.485 163.777 1.00 98.04  ? 262  VAL A CA  1 
ATOM   2012 C C   . VAL A 1 262 ? 135.659 130.247 164.234 1.00 100.30 ? 262  VAL A C   1 
ATOM   2013 O O   . VAL A 1 262 ? 135.361 129.674 165.288 1.00 99.36  ? 262  VAL A O   1 
ATOM   2014 C CB  . VAL A 1 262 ? 133.799 131.129 162.766 1.00 98.69  ? 262  VAL A CB  1 
ATOM   2015 C CG1 . VAL A 1 262 ? 132.864 130.093 163.359 1.00 99.96  ? 262  VAL A CG1 1 
ATOM   2016 C CG2 . VAL A 1 262 ? 133.026 132.372 162.356 1.00 95.14  ? 262  VAL A CG2 1 
ATOM   2017 N N   . THR A 1 263 ? 136.642 129.807 163.447 1.00 95.71  ? 263  THR A N   1 
ATOM   2018 C CA  . THR A 1 263 ? 137.437 128.647 163.832 1.00 92.27  ? 263  THR A CA  1 
ATOM   2019 C C   . THR A 1 263 ? 138.150 128.895 165.153 1.00 97.70  ? 263  THR A C   1 
ATOM   2020 O O   . THR A 1 263 ? 138.104 128.064 166.068 1.00 101.09 ? 263  THR A O   1 
ATOM   2021 C CB  . THR A 1 263 ? 138.449 128.321 162.735 1.00 95.86  ? 263  THR A CB  1 
ATOM   2022 O OG1 . THR A 1 263 ? 137.798 128.329 161.460 1.00 101.59 ? 263  THR A OG1 1 
ATOM   2023 C CG2 . THR A 1 263 ? 139.073 126.957 162.969 1.00 99.38  ? 263  THR A CG2 1 
ATOM   2024 N N   . MET A 1 264 ? 138.815 130.045 165.271 1.00 97.97  ? 264  MET A N   1 
ATOM   2025 C CA  . MET A 1 264 ? 139.510 130.371 166.509 1.00 94.93  ? 264  MET A CA  1 
ATOM   2026 C C   . MET A 1 264 ? 138.546 130.469 167.680 1.00 95.47  ? 264  MET A C   1 
ATOM   2027 O O   . MET A 1 264 ? 138.846 129.971 168.770 1.00 99.32  ? 264  MET A O   1 
ATOM   2028 C CB  . MET A 1 264 ? 140.280 131.679 166.347 1.00 89.20  ? 264  MET A CB  1 
ATOM   2029 C CG  . MET A 1 264 ? 141.689 131.489 165.829 1.00 93.12  ? 264  MET A CG  1 
ATOM   2030 S SD  . MET A 1 264 ? 142.633 133.020 165.817 1.00 111.56 ? 264  MET A SD  1 
ATOM   2031 C CE  . MET A 1 264 ? 144.294 132.369 165.893 1.00 101.39 ? 264  MET A CE  1 
ATOM   2032 N N   . ARG A 1 265 ? 137.390 131.103 167.480 1.00 98.36  ? 265  ARG A N   1 
ATOM   2033 C CA  . ARG A 1 265 ? 136.420 131.212 168.564 1.00 104.26 ? 265  ARG A CA  1 
ATOM   2034 C C   . ARG A 1 265 ? 135.960 129.835 169.022 1.00 104.07 ? 265  ARG A C   1 
ATOM   2035 O O   . ARG A 1 265 ? 135.871 129.565 170.224 1.00 104.87 ? 265  ARG A O   1 
ATOM   2036 C CB  . ARG A 1 265 ? 135.223 132.047 168.119 1.00 104.55 ? 265  ARG A CB  1 
ATOM   2037 C CG  . ARG A 1 265 ? 134.226 132.280 169.236 1.00 103.61 ? 265  ARG A CG  1 
ATOM   2038 C CD  . ARG A 1 265 ? 133.461 133.588 169.052 1.00 99.64  ? 265  ARG A CD  1 
ATOM   2039 N NE  . ARG A 1 265 ? 132.351 133.485 168.110 1.00 103.38 ? 265  ARG A NE  1 
ATOM   2040 C CZ  . ARG A 1 265 ? 131.375 132.587 168.172 1.00 104.71 ? 265  ARG A CZ  1 
ATOM   2041 N NH1 . ARG A 1 265 ? 131.248 131.768 169.204 1.00 103.24 ? 265  ARG A NH1 1 
ATOM   2042 N NH2 . ARG A 1 265 ? 130.483 132.530 167.188 1.00 102.23 ? 265  ARG A NH2 1 
ATOM   2043 N N   . VAL A 1 266 ? 135.660 128.947 168.072 1.00 101.54 ? 266  VAL A N   1 
ATOM   2044 C CA  . VAL A 1 266 ? 135.165 127.619 168.422 1.00 102.74 ? 266  VAL A CA  1 
ATOM   2045 C C   . VAL A 1 266 ? 136.249 126.816 169.125 1.00 103.67 ? 266  VAL A C   1 
ATOM   2046 O O   . VAL A 1 266 ? 135.969 126.032 170.039 1.00 103.16 ? 266  VAL A O   1 
ATOM   2047 C CB  . VAL A 1 266 ? 134.653 126.893 167.165 1.00 95.45  ? 266  VAL A CB  1 
ATOM   2048 C CG1 . VAL A 1 266 ? 134.386 125.426 167.469 1.00 95.42  ? 266  VAL A CG1 1 
ATOM   2049 C CG2 . VAL A 1 266 ? 133.402 127.570 166.633 1.00 100.87 ? 266  VAL A CG2 1 
ATOM   2050 N N   . ALA A 1 267 ? 137.505 126.994 168.709 1.00 99.03  ? 267  ALA A N   1 
ATOM   2051 C CA  . ALA A 1 267 ? 138.588 126.210 169.291 1.00 94.74  ? 267  ALA A CA  1 
ATOM   2052 C C   . ALA A 1 267 ? 138.682 126.410 170.796 1.00 101.54 ? 267  ALA A C   1 
ATOM   2053 O O   . ALA A 1 267 ? 139.079 125.489 171.519 1.00 102.65 ? 267  ALA A O   1 
ATOM   2054 C CB  . ALA A 1 267 ? 139.912 126.577 168.626 1.00 97.41  ? 267  ALA A CB  1 
ATOM   2055 N N   . GLU A 1 268 ? 138.322 127.596 171.290 1.00 119.48 ? 268  GLU A N   1 
ATOM   2056 C CA  . GLU A 1 268 ? 138.403 127.851 172.723 1.00 122.55 ? 268  GLU A CA  1 
ATOM   2057 C C   . GLU A 1 268 ? 137.447 126.974 173.519 1.00 122.53 ? 268  GLU A C   1 
ATOM   2058 O O   . GLU A 1 268 ? 137.794 126.549 174.625 1.00 123.76 ? 268  GLU A O   1 
ATOM   2059 C CB  . GLU A 1 268 ? 138.128 129.328 173.009 1.00 121.58 ? 268  GLU A CB  1 
ATOM   2060 C CG  . GLU A 1 268 ? 139.388 130.137 173.278 1.00 121.59 ? 268  GLU A CG  1 
ATOM   2061 C CD  . GLU A 1 268 ? 139.123 131.626 173.373 1.00 124.14 ? 268  GLU A CD  1 
ATOM   2062 O OE1 . GLU A 1 268 ? 138.283 132.132 172.599 1.00 122.72 ? 268  GLU A OE1 1 
ATOM   2063 O OE2 . GLU A 1 268 ? 139.758 132.292 174.217 1.00 122.90 ? 268  GLU A OE2 1 
ATOM   2064 N N   . GLU A 1 269 ? 136.261 126.689 172.984 1.00 124.28 ? 269  GLU A N   1 
ATOM   2065 C CA  . GLU A 1 269 ? 135.331 125.782 173.639 1.00 125.62 ? 269  GLU A CA  1 
ATOM   2066 C C   . GLU A 1 269 ? 135.664 124.321 173.381 1.00 125.29 ? 269  GLU A C   1 
ATOM   2067 O O   . GLU A 1 269 ? 135.101 123.444 174.045 1.00 127.55 ? 269  GLU A O   1 
ATOM   2068 C CB  . GLU A 1 269 ? 133.885 126.048 173.191 1.00 125.74 ? 269  GLU A CB  1 
ATOM   2069 C CG  . GLU A 1 269 ? 133.321 127.456 173.450 1.00 128.77 ? 269  GLU A CG  1 
ATOM   2070 C CD  . GLU A 1 269 ? 134.148 128.584 172.866 1.00 133.67 ? 269  GLU A CD  1 
ATOM   2071 O OE1 . GLU A 1 269 ? 133.747 129.756 173.024 1.00 136.38 ? 269  GLU A OE1 1 
ATOM   2072 O OE2 . GLU A 1 269 ? 135.197 128.308 172.253 1.00 132.10 ? 269  GLU A OE2 1 
ATOM   2073 N N   . LEU A 1 270 ? 136.564 124.042 172.438 1.00 114.50 ? 270  LEU A N   1 
ATOM   2074 C CA  . LEU A 1 270 ? 136.949 122.663 172.166 1.00 114.57 ? 270  LEU A CA  1 
ATOM   2075 C C   . LEU A 1 270 ? 137.638 122.030 173.366 1.00 115.36 ? 270  LEU A C   1 
ATOM   2076 O O   . LEU A 1 270 ? 137.489 120.826 173.600 1.00 113.24 ? 270  LEU A O   1 
ATOM   2077 C CB  . LEU A 1 270 ? 137.864 122.615 170.944 1.00 113.35 ? 270  LEU A CB  1 
ATOM   2078 C CG  . LEU A 1 270 ? 137.992 121.270 170.230 1.00 108.08 ? 270  LEU A CG  1 
ATOM   2079 C CD1 . LEU A 1 270 ? 136.659 120.841 169.643 1.00 109.97 ? 270  LEU A CD1 1 
ATOM   2080 C CD2 . LEU A 1 270 ? 139.054 121.363 169.150 1.00 107.27 ? 270  LEU A CD2 1 
ATOM   2081 N N   . GLY A 1 271 ? 138.385 122.818 174.132 1.00 118.33 ? 271  GLY A N   1 
ATOM   2082 C CA  . GLY A 1 271 ? 139.110 122.331 175.292 1.00 122.72 ? 271  GLY A CA  1 
ATOM   2083 C C   . GLY A 1 271 ? 140.617 122.408 175.173 1.00 120.91 ? 271  GLY A C   1 
ATOM   2084 O O   . GLY A 1 271 ? 141.306 122.333 176.201 1.00 114.07 ? 271  GLY A O   1 
ATOM   2085 N N   . VAL A 1 272 ? 141.166 122.553 173.972 1.00 113.71 ? 272  VAL A N   1 
ATOM   2086 C CA  . VAL A 1 272 ? 142.611 122.666 173.792 1.00 111.61 ? 272  VAL A CA  1 
ATOM   2087 C C   . VAL A 1 272 ? 143.071 123.967 174.440 1.00 113.40 ? 272  VAL A C   1 
ATOM   2088 O O   . VAL A 1 272 ? 142.339 124.966 174.398 1.00 112.47 ? 272  VAL A O   1 
ATOM   2089 C CB  . VAL A 1 272 ? 142.999 122.627 172.306 1.00 110.40 ? 272  VAL A CB  1 
ATOM   2090 C CG1 . VAL A 1 272 ? 142.632 121.287 171.695 1.00 105.64 ? 272  VAL A CG1 1 
ATOM   2091 C CG2 . VAL A 1 272 ? 142.340 123.773 171.547 1.00 110.56 ? 272  VAL A CG2 1 
ATOM   2092 N N   . PRO A 1 273 ? 144.257 124.011 175.044 1.00 106.27 ? 273  PRO A N   1 
ATOM   2093 C CA  . PRO A 1 273 ? 144.736 125.276 175.608 1.00 105.29 ? 273  PRO A CA  1 
ATOM   2094 C C   . PRO A 1 273 ? 144.918 126.322 174.521 1.00 106.63 ? 273  PRO A C   1 
ATOM   2095 O O   . PRO A 1 273 ? 145.305 126.011 173.392 1.00 101.45 ? 273  PRO A O   1 
ATOM   2096 C CB  . PRO A 1 273 ? 146.068 124.897 176.262 1.00 100.73 ? 273  PRO A CB  1 
ATOM   2097 C CG  . PRO A 1 273 ? 146.503 123.670 175.559 1.00 102.32 ? 273  PRO A CG  1 
ATOM   2098 C CD  . PRO A 1 273 ? 145.262 122.941 175.150 1.00 105.43 ? 273  PRO A CD  1 
ATOM   2099 N N   . GLU A 1 274 ? 144.636 127.576 174.877 1.00 117.68 ? 274  GLU A N   1 
ATOM   2100 C CA  . GLU A 1 274 ? 144.656 128.645 173.884 1.00 116.97 ? 274  GLU A CA  1 
ATOM   2101 C C   . GLU A 1 274 ? 146.043 128.837 173.285 1.00 116.30 ? 274  GLU A C   1 
ATOM   2102 O O   . GLU A 1 274 ? 146.165 129.291 172.142 1.00 121.94 ? 274  GLU A O   1 
ATOM   2103 C CB  . GLU A 1 274 ? 144.148 129.946 174.514 1.00 115.49 ? 274  GLU A CB  1 
ATOM   2104 C CG  . GLU A 1 274 ? 145.227 130.897 175.022 1.00 118.03 ? 274  GLU A CG  1 
ATOM   2105 C CD  . GLU A 1 274 ? 146.082 130.280 176.111 1.00 121.27 ? 274  GLU A CD  1 
ATOM   2106 O OE1 . GLU A 1 274 ? 147.169 130.825 176.397 1.00 122.11 ? 274  GLU A OE1 1 
ATOM   2107 O OE2 . GLU A 1 274 ? 145.669 129.246 176.677 1.00 121.19 ? 274  GLU A OE2 1 
ATOM   2108 N N   . SER A 1 275 ? 147.095 128.494 174.029 1.00 101.34 ? 275  SER A N   1 
ATOM   2109 C CA  . SER A 1 275 ? 148.446 128.737 173.538 1.00 98.87  ? 275  SER A CA  1 
ATOM   2110 C C   . SER A 1 275 ? 148.732 127.958 172.262 1.00 102.79 ? 275  SER A C   1 
ATOM   2111 O O   . SER A 1 275 ? 149.318 128.508 171.323 1.00 100.98 ? 275  SER A O   1 
ATOM   2112 C CB  . SER A 1 275 ? 149.466 128.374 174.615 1.00 102.26 ? 275  SER A CB  1 
ATOM   2113 O OG  . SER A 1 275 ? 149.264 127.052 175.081 1.00 106.16 ? 275  SER A OG  1 
ATOM   2114 N N   . ILE A 1 276 ? 148.330 126.689 172.204 1.00 99.27  ? 276  ILE A N   1 
ATOM   2115 C CA  . ILE A 1 276 ? 148.591 125.891 171.010 1.00 98.29  ? 276  ILE A CA  1 
ATOM   2116 C C   . ILE A 1 276 ? 147.632 126.266 169.891 1.00 94.11  ? 276  ILE A C   1 
ATOM   2117 O O   . ILE A 1 276 ? 148.018 126.298 168.717 1.00 102.06 ? 276  ILE A O   1 
ATOM   2118 C CB  . ILE A 1 276 ? 148.529 124.380 171.310 1.00 97.92  ? 276  ILE A CB  1 
ATOM   2119 C CG1 . ILE A 1 276 ? 148.966 124.051 172.743 1.00 101.92 ? 276  ILE A CG1 1 
ATOM   2120 C CG2 . ILE A 1 276 ? 149.387 123.619 170.319 1.00 98.54  ? 276  ILE A CG2 1 
ATOM   2121 C CD1 . ILE A 1 276 ? 148.642 122.634 173.155 1.00 102.51 ? 276  ILE A CD1 1 
ATOM   2122 N N   . ALA A 1 277 ? 146.368 126.526 170.224 1.00 87.40  ? 277  ALA A N   1 
ATOM   2123 C CA  . ALA A 1 277 ? 145.402 126.884 169.193 1.00 95.35  ? 277  ALA A CA  1 
ATOM   2124 C C   . ALA A 1 277 ? 145.816 128.162 168.480 1.00 95.85  ? 277  ALA A C   1 
ATOM   2125 O O   . ALA A 1 277 ? 145.769 128.239 167.246 1.00 97.02  ? 277  ALA A O   1 
ATOM   2126 C CB  . ALA A 1 277 ? 144.013 127.040 169.809 1.00 92.45  ? 277  ALA A CB  1 
ATOM   2127 N N   . SER A 1 278 ? 146.252 129.168 169.241 1.00 96.27  ? 278  SER A N   1 
ATOM   2128 C CA  . SER A 1 278 ? 146.607 130.448 168.641 1.00 94.61  ? 278  SER A CA  1 
ATOM   2129 C C   . SER A 1 278 ? 147.708 130.284 167.604 1.00 93.81  ? 278  SER A C   1 
ATOM   2130 O O   . SER A 1 278 ? 147.653 130.899 166.535 1.00 104.65 ? 278  SER A O   1 
ATOM   2131 C CB  . SER A 1 278 ? 147.040 131.429 169.728 1.00 99.53  ? 278  SER A CB  1 
ATOM   2132 O OG  . SER A 1 278 ? 145.986 131.669 170.643 1.00 107.29 ? 278  SER A OG  1 
ATOM   2133 N N   . PHE A 1 279 ? 148.720 129.471 167.902 1.00 82.52  ? 279  PHE A N   1 
ATOM   2134 C CA  . PHE A 1 279 ? 149.794 129.263 166.938 1.00 89.08  ? 279  PHE A CA  1 
ATOM   2135 C C   . PHE A 1 279 ? 149.330 128.400 165.770 1.00 99.73  ? 279  PHE A C   1 
ATOM   2136 O O   . PHE A 1 279 ? 149.595 128.723 164.606 1.00 97.96  ? 279  PHE A O   1 
ATOM   2137 C CB  . PHE A 1 279 ? 151.005 128.638 167.632 1.00 81.31  ? 279  PHE A CB  1 
ATOM   2138 C CG  . PHE A 1 279 ? 152.132 128.292 166.697 1.00 86.49  ? 279  PHE A CG  1 
ATOM   2139 C CD1 . PHE A 1 279 ? 152.072 127.162 165.898 1.00 93.79  ? 279  PHE A CD1 1 
ATOM   2140 C CD2 . PHE A 1 279 ? 153.243 129.109 166.603 1.00 93.92  ? 279  PHE A CD2 1 
ATOM   2141 C CE1 . PHE A 1 279 ? 153.101 126.848 165.037 1.00 95.74  ? 279  PHE A CE1 1 
ATOM   2142 C CE2 . PHE A 1 279 ? 154.276 128.800 165.739 1.00 97.60  ? 279  PHE A CE2 1 
ATOM   2143 C CZ  . PHE A 1 279 ? 154.204 127.668 164.956 1.00 96.73  ? 279  PHE A CZ  1 
ATOM   2144 N N   . THR A 1 280 ? 148.640 127.293 166.056 1.00 108.75 ? 280  THR A N   1 
ATOM   2145 C CA  . THR A 1 280 ? 148.382 126.306 165.013 1.00 95.61  ? 280  THR A CA  1 
ATOM   2146 C C   . THR A 1 280 ? 147.322 126.767 164.020 1.00 96.59  ? 280  THR A C   1 
ATOM   2147 O O   . THR A 1 280 ? 147.512 126.614 162.809 1.00 102.44 ? 280  THR A O   1 
ATOM   2148 C CB  . THR A 1 280 ? 147.964 124.977 165.637 1.00 92.03  ? 280  THR A CB  1 
ATOM   2149 O OG1 . THR A 1 280 ? 146.828 125.178 166.486 1.00 106.63 ? 280  THR A OG1 1 
ATOM   2150 C CG2 . THR A 1 280 ? 149.106 124.387 166.448 1.00 92.00  ? 280  THR A CG2 1 
ATOM   2151 N N   . LEU A 1 281 ? 146.202 127.324 164.496 1.00 93.84  ? 281  LEU A N   1 
ATOM   2152 C CA  . LEU A 1 281 ? 145.097 127.606 163.580 1.00 96.29  ? 281  LEU A CA  1 
ATOM   2153 C C   . LEU A 1 281 ? 145.504 128.567 162.472 1.00 96.75  ? 281  LEU A C   1 
ATOM   2154 O O   . LEU A 1 281 ? 145.225 128.274 161.296 1.00 100.45 ? 281  LEU A O   1 
ATOM   2155 C CB  . LEU A 1 281 ? 143.892 128.128 164.367 1.00 90.99  ? 281  LEU A CB  1 
ATOM   2156 C CG  . LEU A 1 281 ? 143.169 127.124 165.268 1.00 96.72  ? 281  LEU A CG  1 
ATOM   2157 C CD1 . LEU A 1 281 ? 141.868 127.719 165.760 1.00 95.57  ? 281  LEU A CD1 1 
ATOM   2158 C CD2 . LEU A 1 281 ? 142.908 125.810 164.553 1.00 100.30 ? 281  LEU A CD2 1 
ATOM   2159 N N   . PRO A 1 282 ? 146.143 129.705 162.751 1.00 86.14  ? 282  PRO A N   1 
ATOM   2160 C CA  . PRO A 1 282 ? 146.551 130.587 161.647 1.00 90.01  ? 282  PRO A CA  1 
ATOM   2161 C C   . PRO A 1 282 ? 147.474 129.908 160.655 1.00 98.00  ? 282  PRO A C   1 
ATOM   2162 O O   . PRO A 1 282 ? 147.360 130.144 159.447 1.00 97.62  ? 282  PRO A O   1 
ATOM   2163 C CB  . PRO A 1 282 ? 147.245 131.746 162.374 1.00 85.08  ? 282  PRO A CB  1 
ATOM   2164 C CG  . PRO A 1 282 ? 146.683 131.722 163.742 1.00 91.38  ? 282  PRO A CG  1 
ATOM   2165 C CD  . PRO A 1 282 ? 146.496 130.277 164.058 1.00 83.70  ? 282  PRO A CD  1 
ATOM   2166 N N   . LEU A 1 283 ? 148.388 129.062 161.133 1.00 96.73  ? 283  LEU A N   1 
ATOM   2167 C CA  . LEU A 1 283 ? 149.291 128.373 160.218 1.00 92.13  ? 283  LEU A CA  1 
ATOM   2168 C C   . LEU A 1 283 ? 148.526 127.423 159.309 1.00 90.50  ? 283  LEU A C   1 
ATOM   2169 O O   . LEU A 1 283 ? 148.674 127.472 158.083 1.00 92.55  ? 283  LEU A O   1 
ATOM   2170 C CB  . LEU A 1 283 ? 150.360 127.613 161.007 1.00 90.12  ? 283  LEU A CB  1 
ATOM   2171 C CG  . LEU A 1 283 ? 151.828 127.722 160.575 1.00 96.85  ? 283  LEU A CG  1 
ATOM   2172 C CD1 . LEU A 1 283 ? 152.188 129.114 160.095 1.00 97.56  ? 283  LEU A CD1 1 
ATOM   2173 C CD2 . LEU A 1 283 ? 152.741 127.313 161.719 1.00 98.13  ? 283  LEU A CD2 1 
ATOM   2174 N N   . GLY A 1 284 ? 147.683 126.569 159.889 1.00 88.44  ? 284  GLY A N   1 
ATOM   2175 C CA  . GLY A 1 284 ? 146.948 125.614 159.079 1.00 93.28  ? 284  GLY A CA  1 
ATOM   2176 C C   . GLY A 1 284 ? 145.965 126.283 158.138 1.00 97.45  ? 284  GLY A C   1 
ATOM   2177 O O   . GLY A 1 284 ? 145.619 125.730 157.092 1.00 106.15 ? 284  GLY A O   1 
ATOM   2178 N N   . ALA A 1 285 ? 145.498 127.479 158.498 1.00 96.28  ? 285  ALA A N   1 
ATOM   2179 C CA  . ALA A 1 285 ? 144.524 128.173 157.667 1.00 101.17 ? 285  ALA A CA  1 
ATOM   2180 C C   . ALA A 1 285 ? 145.056 128.498 156.280 1.00 105.89 ? 285  ALA A C   1 
ATOM   2181 O O   . ALA A 1 285 ? 144.253 128.753 155.375 1.00 101.00 ? 285  ALA A O   1 
ATOM   2182 C CB  . ALA A 1 285 ? 144.073 129.461 158.355 1.00 99.99  ? 285  ALA A CB  1 
ATOM   2183 N N   . THR A 1 286 ? 146.374 128.503 156.087 1.00 108.42 ? 286  THR A N   1 
ATOM   2184 C CA  . THR A 1 286 ? 146.948 128.820 154.785 1.00 105.60 ? 286  THR A CA  1 
ATOM   2185 C C   . THR A 1 286 ? 147.918 127.736 154.333 1.00 105.82 ? 286  THR A C   1 
ATOM   2186 O O   . THR A 1 286 ? 148.274 127.670 153.152 1.00 102.93 ? 286  THR A O   1 
ATOM   2187 C CB  . THR A 1 286 ? 147.658 130.171 154.830 1.00 100.83 ? 286  THR A CB  1 
ATOM   2188 O OG1 . THR A 1 286 ? 148.547 130.210 155.953 1.00 98.37  ? 286  THR A OG1 1 
ATOM   2189 C CG2 . THR A 1 286 ? 146.643 131.293 154.957 1.00 103.70 ? 286  THR A CG2 1 
ATOM   2190 N N   . ILE A 1 287 ? 148.355 126.887 155.263 1.00 107.83 ? 287  ILE A N   1 
ATOM   2191 C CA  . ILE A 1 287 ? 149.271 125.808 154.915 1.00 104.60 ? 287  ILE A CA  1 
ATOM   2192 C C   . ILE A 1 287 ? 148.518 124.494 154.760 1.00 104.59 ? 287  ILE A C   1 
ATOM   2193 O O   . ILE A 1 287 ? 148.806 123.705 153.855 1.00 103.75 ? 287  ILE A O   1 
ATOM   2194 C CB  . ILE A 1 287 ? 150.384 125.712 155.974 1.00 99.88  ? 287  ILE A CB  1 
ATOM   2195 C CG1 . ILE A 1 287 ? 151.322 126.914 155.843 1.00 95.77  ? 287  ILE A CG1 1 
ATOM   2196 C CG2 . ILE A 1 287 ? 151.154 124.400 155.836 1.00 98.64  ? 287  ILE A CG2 1 
ATOM   2197 C CD1 . ILE A 1 287 ? 152.561 126.840 156.704 1.00 97.59  ? 287  ILE A CD1 1 
ATOM   2198 N N   . ASN A 1 288 ? 147.548 124.239 155.633 1.00 103.20 ? 288  ASN A N   1 
ATOM   2199 C CA  . ASN A 1 288 ? 146.814 122.979 155.652 1.00 94.66  ? 288  ASN A CA  1 
ATOM   2200 C C   . ASN A 1 288 ? 145.511 123.163 154.886 1.00 92.81  ? 288  ASN A C   1 
ATOM   2201 O O   . ASN A 1 288 ? 144.563 123.766 155.397 1.00 100.93 ? 288  ASN A O   1 
ATOM   2202 C CB  . ASN A 1 288 ? 146.542 122.540 157.087 1.00 99.15  ? 288  ASN A CB  1 
ATOM   2203 C CG  . ASN A 1 288 ? 145.873 121.188 157.162 1.00 101.07 ? 288  ASN A CG  1 
ATOM   2204 O OD1 . ASN A 1 288 ? 146.394 120.199 156.649 1.00 104.55 ? 288  ASN A OD1 1 
ATOM   2205 N ND2 . ASN A 1 288 ? 144.709 121.136 157.797 1.00 102.85 ? 288  ASN A ND2 1 
ATOM   2206 N N   . MET A 1 289 ? 145.466 122.641 153.662 1.00 95.43  ? 289  MET A N   1 
ATOM   2207 C CA  . MET A 1 289 ? 144.301 122.763 152.798 1.00 103.35 ? 289  MET A CA  1 
ATOM   2208 C C   . MET A 1 289 ? 144.005 121.400 152.168 1.00 103.07 ? 289  MET A C   1 
ATOM   2209 O O   . MET A 1 289 ? 143.846 121.256 150.960 1.00 105.67 ? 289  MET A O   1 
ATOM   2210 C CB  . MET A 1 289 ? 144.522 123.848 151.748 1.00 102.67 ? 289  MET A CB  1 
ATOM   2211 C CG  . MET A 1 289 ? 144.140 125.234 152.233 1.00 100.97 ? 289  MET A CG  1 
ATOM   2212 S SD  . MET A 1 289 ? 144.147 126.467 150.925 1.00 117.84 ? 289  MET A SD  1 
ATOM   2213 C CE  . MET A 1 289 ? 144.138 127.970 151.894 1.00 107.62 ? 289  MET A CE  1 
ATOM   2214 N N   . ASP A 1 290 ? 143.942 120.370 153.016 1.00 96.32  ? 290  ASP A N   1 
ATOM   2215 C CA  . ASP A 1 290 ? 143.781 119.005 152.524 1.00 101.79 ? 290  ASP A CA  1 
ATOM   2216 C C   . ASP A 1 290 ? 142.611 118.896 151.556 1.00 101.02 ? 290  ASP A C   1 
ATOM   2217 O O   . ASP A 1 290 ? 142.696 118.195 150.541 1.00 109.44 ? 290  ASP A O   1 
ATOM   2218 C CB  . ASP A 1 290 ? 143.584 118.041 153.695 1.00 102.23 ? 290  ASP A CB  1 
ATOM   2219 C CG  . ASP A 1 290 ? 144.487 118.355 154.866 1.00 105.06 ? 290  ASP A CG  1 
ATOM   2220 O OD1 . ASP A 1 290 ? 144.276 119.404 155.506 1.00 109.00 ? 290  ASP A OD1 1 
ATOM   2221 O OD2 . ASP A 1 290 ? 145.411 117.564 155.138 1.00 106.10 ? 290  ASP A OD2 1 
ATOM   2222 N N   . GLY A 1 291 ? 141.506 119.575 151.858 1.00 99.55  ? 291  GLY A N   1 
ATOM   2223 C CA  . GLY A 1 291 ? 140.390 119.580 150.928 1.00 103.76 ? 291  GLY A CA  1 
ATOM   2224 C C   . GLY A 1 291 ? 140.794 120.103 149.566 1.00 102.00 ? 291  GLY A C   1 
ATOM   2225 O O   . GLY A 1 291 ? 140.391 119.565 148.531 1.00 107.05 ? 291  GLY A O   1 
ATOM   2226 N N   . THR A 1 292 ? 141.611 121.158 149.548 1.00 98.87  ? 292  THR A N   1 
ATOM   2227 C CA  . THR A 1 292 ? 142.098 121.681 148.279 1.00 96.93  ? 292  THR A CA  1 
ATOM   2228 C C   . THR A 1 292 ? 142.935 120.645 147.546 1.00 101.72 ? 292  THR A C   1 
ATOM   2229 O O   . THR A 1 292 ? 142.813 120.494 146.329 1.00 103.06 ? 292  THR A O   1 
ATOM   2230 C CB  . THR A 1 292 ? 142.914 122.952 148.504 1.00 95.06  ? 292  THR A CB  1 
ATOM   2231 O OG1 . THR A 1 292 ? 142.141 123.890 149.260 1.00 103.09 ? 292  THR A OG1 1 
ATOM   2232 C CG2 . THR A 1 292 ? 143.305 123.573 147.174 1.00 95.47  ? 292  THR A CG2 1 
ATOM   2233 N N   . ALA A 1 293 ? 143.795 119.923 148.266 1.00 105.29 ? 293  ALA A N   1 
ATOM   2234 C CA  . ALA A 1 293 ? 144.623 118.912 147.619 1.00 104.18 ? 293  ALA A CA  1 
ATOM   2235 C C   . ALA A 1 293 ? 143.762 117.816 147.004 1.00 106.23 ? 293  ALA A C   1 
ATOM   2236 O O   . ALA A 1 293 ? 143.993 117.389 145.865 1.00 112.80 ? 293  ALA A O   1 
ATOM   2237 C CB  . ALA A 1 293 ? 145.610 118.323 148.626 1.00 102.30 ? 293  ALA A CB  1 
ATOM   2238 N N   . LEU A 1 294 ? 142.761 117.344 147.749 1.00 97.90  ? 294  LEU A N   1 
ATOM   2239 C CA  . LEU A 1 294 ? 141.875 116.312 147.220 1.00 97.59  ? 294  LEU A CA  1 
ATOM   2240 C C   . LEU A 1 294 ? 141.138 116.812 145.986 1.00 98.25  ? 294  LEU A C   1 
ATOM   2241 O O   . LEU A 1 294 ? 141.059 116.110 144.967 1.00 103.67 ? 294  LEU A O   1 
ATOM   2242 C CB  . LEU A 1 294 ? 140.888 115.878 148.304 1.00 95.24  ? 294  LEU A CB  1 
ATOM   2243 C CG  . LEU A 1 294 ? 140.045 114.623 148.062 1.00 96.28  ? 294  LEU A CG  1 
ATOM   2244 C CD1 . LEU A 1 294 ? 139.281 114.255 149.321 1.00 98.14  ? 294  LEU A CD1 1 
ATOM   2245 C CD2 . LEU A 1 294 ? 139.080 114.803 146.910 1.00 100.73 ? 294  LEU A CD2 1 
ATOM   2246 N N   . TYR A 1 295 ? 140.599 118.031 146.056 1.00 92.21  ? 295  TYR A N   1 
ATOM   2247 C CA  . TYR A 1 295 ? 139.893 118.593 144.912 1.00 90.25  ? 295  TYR A CA  1 
ATOM   2248 C C   . TYR A 1 295 ? 140.814 118.719 143.709 1.00 96.15  ? 295  TYR A C   1 
ATOM   2249 O O   . TYR A 1 295 ? 140.418 118.425 142.578 1.00 103.86 ? 295  TYR A O   1 
ATOM   2250 C CB  . TYR A 1 295 ? 139.308 119.954 145.275 1.00 93.47  ? 295  TYR A CB  1 
ATOM   2251 C CG  . TYR A 1 295 ? 139.193 120.877 144.089 1.00 92.55  ? 295  TYR A CG  1 
ATOM   2252 C CD1 . TYR A 1 295 ? 138.197 120.705 143.143 1.00 93.98  ? 295  TYR A CD1 1 
ATOM   2253 C CD2 . TYR A 1 295 ? 140.091 121.917 143.913 1.00 97.70  ? 295  TYR A CD2 1 
ATOM   2254 C CE1 . TYR A 1 295 ? 138.096 121.546 142.057 1.00 93.88  ? 295  TYR A CE1 1 
ATOM   2255 C CE2 . TYR A 1 295 ? 139.997 122.762 142.833 1.00 100.32 ? 295  TYR A CE2 1 
ATOM   2256 C CZ  . TYR A 1 295 ? 139.000 122.573 141.908 1.00 100.15 ? 295  TYR A CZ  1 
ATOM   2257 O OH  . TYR A 1 295 ? 138.907 123.418 140.829 1.00 112.27 ? 295  TYR A OH  1 
ATOM   2258 N N   . GLN A 1 296 ? 142.046 119.175 143.932 1.00 101.38 ? 296  GLN A N   1 
ATOM   2259 C CA  . GLN A 1 296 ? 142.975 119.358 142.825 1.00 103.64 ? 296  GLN A CA  1 
ATOM   2260 C C   . GLN A 1 296 ? 143.331 118.026 142.185 1.00 105.94 ? 296  GLN A C   1 
ATOM   2261 O O   . GLN A 1 296 ? 143.394 117.921 140.956 1.00 105.16 ? 296  GLN A O   1 
ATOM   2262 C CB  . GLN A 1 296 ? 144.231 120.077 143.310 1.00 98.37  ? 296  GLN A CB  1 
ATOM   2263 C CG  . GLN A 1 296 ? 143.977 121.508 143.745 1.00 100.67 ? 296  GLN A CG  1 
ATOM   2264 C CD  . GLN A 1 296 ? 145.022 122.470 143.238 1.00 109.58 ? 296  GLN A CD  1 
ATOM   2265 O OE1 . GLN A 1 296 ? 144.986 122.890 142.084 1.00 116.54 ? 296  GLN A OE1 1 
ATOM   2266 N NE2 . GLN A 1 296 ? 145.957 122.836 144.103 1.00 106.10 ? 296  GLN A NE2 1 
ATOM   2267 N N   . GLY A 1 297 ? 143.560 116.994 142.996 1.00 100.30 ? 297  GLY A N   1 
ATOM   2268 C CA  . GLY A 1 297 ? 143.829 115.683 142.429 1.00 98.16  ? 297  GLY A CA  1 
ATOM   2269 C C   . GLY A 1 297 ? 142.668 115.175 141.597 1.00 98.21  ? 297  GLY A C   1 
ATOM   2270 O O   . GLY A 1 297 ? 142.848 114.699 140.469 1.00 107.02 ? 297  GLY A O   1 
ATOM   2271 N N   . VAL A 1 298 ? 141.452 115.285 142.137 1.00 90.91  ? 298  VAL A N   1 
ATOM   2272 C CA  . VAL A 1 298 ? 140.281 114.804 141.411 1.00 88.21  ? 298  VAL A CA  1 
ATOM   2273 C C   . VAL A 1 298 ? 140.120 115.571 140.106 1.00 92.41  ? 298  VAL A C   1 
ATOM   2274 O O   . VAL A 1 298 ? 139.856 114.985 139.049 1.00 104.17 ? 298  VAL A O   1 
ATOM   2275 C CB  . VAL A 1 298 ? 139.022 114.915 142.289 1.00 94.68  ? 298  VAL A CB  1 
ATOM   2276 C CG1 . VAL A 1 298 ? 137.774 114.707 141.451 1.00 98.69  ? 298  VAL A CG1 1 
ATOM   2277 C CG2 . VAL A 1 298 ? 139.083 113.906 143.415 1.00 99.15  ? 298  VAL A CG2 1 
ATOM   2278 N N   . ALA A 1 299 ? 140.274 116.894 140.159 1.00 101.37 ? 299  ALA A N   1 
ATOM   2279 C CA  . ALA A 1 299 ? 140.105 117.708 138.961 1.00 109.33 ? 299  ALA A CA  1 
ATOM   2280 C C   . ALA A 1 299 ? 141.171 117.390 137.924 1.00 105.69 ? 299  ALA A C   1 
ATOM   2281 O O   . ALA A 1 299 ? 140.884 117.350 136.723 1.00 107.19 ? 299  ALA A O   1 
ATOM   2282 C CB  . ALA A 1 299 ? 140.139 119.191 139.326 1.00 109.42 ? 299  ALA A CB  1 
ATOM   2283 N N   . ALA A 1 300 ? 142.412 117.177 138.362 1.00 98.71  ? 300  ALA A N   1 
ATOM   2284 C CA  . ALA A 1 300 ? 143.470 116.840 137.419 1.00 101.62 ? 300  ALA A CA  1 
ATOM   2285 C C   . ALA A 1 300 ? 143.180 115.517 136.728 1.00 102.93 ? 300  ALA A C   1 
ATOM   2286 O O   . ALA A 1 300 ? 143.330 115.400 135.505 1.00 112.57 ? 300  ALA A O   1 
ATOM   2287 C CB  . ALA A 1 300 ? 144.816 116.788 138.139 1.00 102.44 ? 300  ALA A CB  1 
ATOM   2288 N N   . ILE A 1 301 ? 142.750 114.510 137.490 1.00 106.19 ? 301  ILE A N   1 
ATOM   2289 C CA  . ILE A 1 301 ? 142.414 113.239 136.859 1.00 103.13 ? 301  ILE A CA  1 
ATOM   2290 C C   . ILE A 1 301 ? 141.244 113.411 135.900 1.00 104.77 ? 301  ILE A C   1 
ATOM   2291 O O   . ILE A 1 301 ? 141.239 112.834 134.805 1.00 108.06 ? 301  ILE A O   1 
ATOM   2292 C CB  . ILE A 1 301 ? 142.114 112.166 137.919 1.00 104.81 ? 301  ILE A CB  1 
ATOM   2293 C CG1 . ILE A 1 301 ? 143.391 111.786 138.672 1.00 113.19 ? 301  ILE A CG1 1 
ATOM   2294 C CG2 . ILE A 1 301 ? 141.496 110.940 137.268 1.00 101.34 ? 301  ILE A CG2 1 
ATOM   2295 C CD1 . ILE A 1 301 ? 144.480 111.184 137.798 1.00 111.49 ? 301  ILE A CD1 1 
ATOM   2296 N N   . PHE A 1 302 ? 140.234 114.192 136.290 1.00 108.67 ? 302  PHE A N   1 
ATOM   2297 C CA  . PHE A 1 302 ? 139.086 114.407 135.416 1.00 114.10 ? 302  PHE A CA  1 
ATOM   2298 C C   . PHE A 1 302 ? 139.513 115.062 134.111 1.00 111.08 ? 302  PHE A C   1 
ATOM   2299 O O   . PHE A 1 302 ? 139.076 114.660 133.027 1.00 115.46 ? 302  PHE A O   1 
ATOM   2300 C CB  . PHE A 1 302 ? 138.042 115.263 136.131 1.00 109.38 ? 302  PHE A CB  1 
ATOM   2301 C CG  . PHE A 1 302 ? 137.015 115.857 135.214 1.00 110.14 ? 302  PHE A CG  1 
ATOM   2302 C CD1 . PHE A 1 302 ? 135.880 115.146 134.872 1.00 112.03 ? 302  PHE A CD1 1 
ATOM   2303 C CD2 . PHE A 1 302 ? 137.184 117.129 134.695 1.00 109.38 ? 302  PHE A CD2 1 
ATOM   2304 C CE1 . PHE A 1 302 ? 134.933 115.691 134.029 1.00 113.55 ? 302  PHE A CE1 1 
ATOM   2305 C CE2 . PHE A 1 302 ? 136.242 117.677 133.851 1.00 109.77 ? 302  PHE A CE2 1 
ATOM   2306 C CZ  . PHE A 1 302 ? 135.115 116.959 133.518 1.00 113.53 ? 302  PHE A CZ  1 
ATOM   2307 N N   . VAL A 1 303 ? 140.374 116.075 134.196 1.00 96.05  ? 303  VAL A N   1 
ATOM   2308 C CA  . VAL A 1 303 ? 140.858 116.736 132.990 1.00 96.53  ? 303  VAL A CA  1 
ATOM   2309 C C   . VAL A 1 303 ? 141.625 115.749 132.124 1.00 103.33 ? 303  VAL A C   1 
ATOM   2310 O O   . VAL A 1 303 ? 141.462 115.717 130.899 1.00 102.67 ? 303  VAL A O   1 
ATOM   2311 C CB  . VAL A 1 303 ? 141.724 117.954 133.356 1.00 97.34  ? 303  VAL A CB  1 
ATOM   2312 C CG1 . VAL A 1 303 ? 142.421 118.496 132.122 1.00 102.64 ? 303  VAL A CG1 1 
ATOM   2313 C CG2 . VAL A 1 303 ? 140.877 119.031 134.008 1.00 105.45 ? 303  VAL A CG2 1 
ATOM   2314 N N   . ALA A 1 304 ? 142.471 114.925 132.745 1.00 118.92 ? 304  ALA A N   1 
ATOM   2315 C CA  . ALA A 1 304 ? 143.240 113.952 131.979 1.00 117.76 ? 304  ALA A CA  1 
ATOM   2316 C C   . ALA A 1 304 ? 142.319 113.004 131.224 1.00 116.33 ? 304  ALA A C   1 
ATOM   2317 O O   . ALA A 1 304 ? 142.534 112.723 130.039 1.00 118.30 ? 304  ALA A O   1 
ATOM   2318 C CB  . ALA A 1 304 ? 144.168 113.171 132.907 1.00 119.34 ? 304  ALA A CB  1 
ATOM   2319 N N   . GLN A 1 305 ? 141.280 112.502 131.893 1.00 117.26 ? 305  GLN A N   1 
ATOM   2320 C CA  . GLN A 1 305 ? 140.354 111.603 131.212 1.00 122.83 ? 305  GLN A CA  1 
ATOM   2321 C C   . GLN A 1 305 ? 139.559 112.331 130.137 1.00 122.38 ? 305  GLN A C   1 
ATOM   2322 O O   . GLN A 1 305 ? 139.197 111.729 129.120 1.00 124.15 ? 305  GLN A O   1 
ATOM   2323 C CB  . GLN A 1 305 ? 139.398 110.944 132.205 1.00 122.42 ? 305  GLN A CB  1 
ATOM   2324 C CG  . GLN A 1 305 ? 140.003 110.584 133.544 1.00 121.06 ? 305  GLN A CG  1 
ATOM   2325 C CD  . GLN A 1 305 ? 139.512 109.248 134.053 1.00 122.94 ? 305  GLN A CD  1 
ATOM   2326 O OE1 . GLN A 1 305 ? 138.311 108.982 134.066 1.00 121.89 ? 305  GLN A OE1 1 
ATOM   2327 N NE2 . GLN A 1 305 ? 140.439 108.397 134.472 1.00 123.44 ? 305  GLN A NE2 1 
ATOM   2328 N N   . ALA A 1 306 ? 139.281 113.620 130.338 1.00 123.55 ? 306  ALA A N   1 
ATOM   2329 C CA  . ALA A 1 306 ? 138.476 114.360 129.375 1.00 126.98 ? 306  ALA A CA  1 
ATOM   2330 C C   . ALA A 1 306 ? 139.125 114.424 128.001 1.00 127.45 ? 306  ALA A C   1 
ATOM   2331 O O   . ALA A 1 306 ? 138.429 114.681 127.013 1.00 128.42 ? 306  ALA A O   1 
ATOM   2332 C CB  . ALA A 1 306 ? 138.218 115.776 129.889 1.00 125.62 ? 306  ALA A CB  1 
ATOM   2333 N N   . TYR A 1 307 ? 140.437 114.201 127.911 1.00 119.77 ? 307  TYR A N   1 
ATOM   2334 C CA  . TYR A 1 307 ? 141.150 114.269 126.641 1.00 120.30 ? 307  TYR A CA  1 
ATOM   2335 C C   . TYR A 1 307 ? 141.913 112.984 126.342 1.00 120.10 ? 307  TYR A C   1 
ATOM   2336 O O   . TYR A 1 307 ? 142.947 113.022 125.669 1.00 119.51 ? 307  TYR A O   1 
ATOM   2337 C CB  . TYR A 1 307 ? 142.093 115.472 126.631 1.00 117.62 ? 307  TYR A CB  1 
ATOM   2338 C CG  . TYR A 1 307 ? 141.359 116.790 126.703 1.00 123.21 ? 307  TYR A CG  1 
ATOM   2339 C CD1 . TYR A 1 307 ? 140.751 117.328 125.577 1.00 123.86 ? 307  TYR A CD1 1 
ATOM   2340 C CD2 . TYR A 1 307 ? 141.264 117.491 127.896 1.00 122.88 ? 307  TYR A CD2 1 
ATOM   2341 C CE1 . TYR A 1 307 ? 140.073 118.529 125.637 1.00 124.55 ? 307  TYR A CE1 1 
ATOM   2342 C CE2 . TYR A 1 307 ? 140.589 118.694 127.965 1.00 122.65 ? 307  TYR A CE2 1 
ATOM   2343 C CZ  . TYR A 1 307 ? 139.995 119.208 126.832 1.00 124.51 ? 307  TYR A CZ  1 
ATOM   2344 O OH  . TYR A 1 307 ? 139.322 120.405 126.895 1.00 122.63 ? 307  TYR A OH  1 
ATOM   2345 N N   . GLY A 1 308 ? 141.426 111.846 126.835 1.00 114.83 ? 308  GLY A N   1 
ATOM   2346 C CA  . GLY A 1 308 ? 141.965 110.554 126.471 1.00 113.27 ? 308  GLY A CA  1 
ATOM   2347 C C   . GLY A 1 308 ? 143.312 110.211 127.061 1.00 115.00 ? 308  GLY A C   1 
ATOM   2348 O O   . GLY A 1 308 ? 143.706 109.039 127.011 1.00 117.57 ? 308  GLY A O   1 
ATOM   2349 N N   . VAL A 1 309 ? 144.039 111.178 127.618 1.00 118.25 ? 309  VAL A N   1 
ATOM   2350 C CA  . VAL A 1 309 ? 145.365 110.889 128.150 1.00 121.68 ? 309  VAL A CA  1 
ATOM   2351 C C   . VAL A 1 309 ? 145.217 110.099 129.440 1.00 120.42 ? 309  VAL A C   1 
ATOM   2352 O O   . VAL A 1 309 ? 144.546 110.537 130.382 1.00 117.83 ? 309  VAL A O   1 
ATOM   2353 C CB  . VAL A 1 309 ? 146.155 112.182 128.374 1.00 117.28 ? 309  VAL A CB  1 
ATOM   2354 C CG1 . VAL A 1 309 ? 147.496 111.876 129.024 1.00 112.92 ? 309  VAL A CG1 1 
ATOM   2355 C CG2 . VAL A 1 309 ? 146.358 112.922 127.060 1.00 115.61 ? 309  VAL A CG2 1 
ATOM   2356 N N   . GLU A 1 310 ? 145.843 108.927 129.488 1.00 126.20 ? 310  GLU A N   1 
ATOM   2357 C CA  . GLU A 1 310 ? 145.881 108.094 130.682 1.00 127.52 ? 310  GLU A CA  1 
ATOM   2358 C C   . GLU A 1 310 ? 147.281 108.184 131.272 1.00 129.88 ? 310  GLU A C   1 
ATOM   2359 O O   . GLU A 1 310 ? 148.270 107.954 130.569 1.00 130.35 ? 310  GLU A O   1 
ATOM   2360 C CB  . GLU A 1 310 ? 145.516 106.647 130.354 1.00 127.77 ? 310  GLU A CB  1 
ATOM   2361 C CG  . GLU A 1 310 ? 145.215 105.795 131.575 1.00 133.60 ? 310  GLU A CG  1 
ATOM   2362 C CD  . GLU A 1 310 ? 144.356 104.591 131.245 1.00 136.63 ? 310  GLU A CD  1 
ATOM   2363 O OE1 . GLU A 1 310 ? 144.459 104.079 130.110 1.00 133.75 ? 310  GLU A OE1 1 
ATOM   2364 O OE2 . GLU A 1 310 ? 143.578 104.155 132.119 1.00 137.95 ? 310  GLU A OE2 1 
ATOM   2365 N N   . LEU A 1 311 ? 147.361 108.517 132.556 1.00 121.58 ? 311  LEU A N   1 
ATOM   2366 C CA  . LEU A 1 311 ? 148.640 108.812 133.182 1.00 118.94 ? 311  LEU A CA  1 
ATOM   2367 C C   . LEU A 1 311 ? 149.346 107.537 133.616 1.00 119.11 ? 311  LEU A C   1 
ATOM   2368 O O   . LEU A 1 311 ? 148.709 106.553 134.002 1.00 117.87 ? 311  LEU A O   1 
ATOM   2369 C CB  . LEU A 1 311 ? 148.443 109.718 134.396 1.00 118.72 ? 311  LEU A CB  1 
ATOM   2370 C CG  . LEU A 1 311 ? 147.828 111.098 134.156 1.00 118.75 ? 311  LEU A CG  1 
ATOM   2371 C CD1 . LEU A 1 311 ? 148.325 111.716 132.858 1.00 114.72 ? 311  LEU A CD1 1 
ATOM   2372 C CD2 . LEU A 1 311 ? 146.311 111.010 134.163 1.00 119.51 ? 311  LEU A CD2 1 
ATOM   2373 N N   . THR A 1 312 ? 150.673 107.561 133.547 1.00 121.74 ? 312  THR A N   1 
ATOM   2374 C CA  . THR A 1 312 ? 151.479 106.508 134.139 1.00 121.61 ? 312  THR A CA  1 
ATOM   2375 C C   . THR A 1 312 ? 151.626 106.749 135.639 1.00 120.14 ? 312  THR A C   1 
ATOM   2376 O O   . THR A 1 312 ? 151.226 107.788 136.171 1.00 121.44 ? 312  THR A O   1 
ATOM   2377 C CB  . THR A 1 312 ? 152.856 106.449 133.483 1.00 121.04 ? 312  THR A CB  1 
ATOM   2378 O OG1 . THR A 1 312 ? 153.532 107.698 133.670 1.00 123.18 ? 312  THR A OG1 1 
ATOM   2379 C CG2 . THR A 1 312 ? 152.727 106.161 131.995 1.00 116.80 ? 312  THR A CG2 1 
ATOM   2380 N N   . LEU A 1 313 ? 152.218 105.770 136.325 1.00 118.28 ? 313  LEU A N   1 
ATOM   2381 C CA  . LEU A 1 313 ? 152.396 105.898 137.767 1.00 119.83 ? 313  LEU A CA  1 
ATOM   2382 C C   . LEU A 1 313 ? 153.224 107.133 138.097 1.00 120.09 ? 313  LEU A C   1 
ATOM   2383 O O   . LEU A 1 313 ? 152.873 107.907 138.995 1.00 121.15 ? 313  LEU A O   1 
ATOM   2384 C CB  . LEU A 1 313 ? 153.062 104.639 138.325 1.00 122.11 ? 313  LEU A CB  1 
ATOM   2385 C CG  . LEU A 1 313 ? 153.873 104.752 139.622 1.00 122.12 ? 313  LEU A CG  1 
ATOM   2386 C CD1 . LEU A 1 313 ? 153.057 105.361 140.761 1.00 120.24 ? 313  LEU A CD1 1 
ATOM   2387 C CD2 . LEU A 1 313 ? 154.413 103.394 140.028 1.00 120.78 ? 313  LEU A CD2 1 
ATOM   2388 N N   . GLY A 1 314 ? 154.319 107.347 137.366 1.00 116.64 ? 314  GLY A N   1 
ATOM   2389 C CA  . GLY A 1 314 ? 155.152 108.507 137.635 1.00 118.28 ? 314  GLY A CA  1 
ATOM   2390 C C   . GLY A 1 314 ? 154.389 109.810 137.513 1.00 120.47 ? 314  GLY A C   1 
ATOM   2391 O O   . GLY A 1 314 ? 154.553 110.716 138.333 1.00 125.63 ? 314  GLY A O   1 
ATOM   2392 N N   . GLN A 1 315 ? 153.538 109.922 136.492 1.00 114.63 ? 315  GLN A N   1 
ATOM   2393 C CA  . GLN A 1 315 ? 152.748 111.136 136.328 1.00 115.38 ? 315  GLN A CA  1 
ATOM   2394 C C   . GLN A 1 315 ? 151.817 111.350 137.513 1.00 115.52 ? 315  GLN A C   1 
ATOM   2395 O O   . GLN A 1 315 ? 151.682 112.474 138.010 1.00 110.07 ? 315  GLN A O   1 
ATOM   2396 C CB  . GLN A 1 315 ? 151.953 111.069 135.026 1.00 115.06 ? 315  GLN A CB  1 
ATOM   2397 C CG  . GLN A 1 315 ? 152.795 111.263 133.778 1.00 121.31 ? 315  GLN A CG  1 
ATOM   2398 C CD  . GLN A 1 315 ? 152.116 110.738 132.529 1.00 123.35 ? 315  GLN A CD  1 
ATOM   2399 O OE1 . GLN A 1 315 ? 151.666 109.593 132.490 1.00 124.52 ? 315  GLN A OE1 1 
ATOM   2400 N NE2 . GLN A 1 315 ? 152.039 111.573 131.501 1.00 122.23 ? 315  GLN A NE2 1 
ATOM   2401 N N   . GLN A 1 316 ? 151.168 110.284 137.983 1.00 118.08 ? 316  GLN A N   1 
ATOM   2402 C CA  . GLN A 1 316 ? 150.238 110.416 139.099 1.00 116.51 ? 316  GLN A CA  1 
ATOM   2403 C C   . GLN A 1 316 ? 150.959 110.875 140.362 1.00 121.52 ? 316  GLN A C   1 
ATOM   2404 O O   . GLN A 1 316 ? 150.453 111.722 141.107 1.00 127.96 ? 316  GLN A O   1 
ATOM   2405 C CB  . GLN A 1 316 ? 149.519 109.087 139.333 1.00 114.67 ? 316  GLN A CB  1 
ATOM   2406 C CG  . GLN A 1 316 ? 148.585 108.695 138.199 1.00 114.56 ? 316  GLN A CG  1 
ATOM   2407 C CD  . GLN A 1 316 ? 147.420 107.845 138.662 1.00 117.22 ? 316  GLN A CD  1 
ATOM   2408 O OE1 . GLN A 1 316 ? 146.274 108.085 138.284 1.00 119.34 ? 316  GLN A OE1 1 
ATOM   2409 N NE2 . GLN A 1 316 ? 147.708 106.839 139.479 1.00 115.88 ? 316  GLN A NE2 1 
ATOM   2410 N N   . LEU A 1 317 ? 152.146 110.324 140.623 1.00 119.42 ? 317  LEU A N   1 
ATOM   2411 C CA  . LEU A 1 317 ? 152.917 110.766 141.780 1.00 118.24 ? 317  LEU A CA  1 
ATOM   2412 C C   . LEU A 1 317 ? 153.331 112.226 141.642 1.00 117.40 ? 317  LEU A C   1 
ATOM   2413 O O   . LEU A 1 317 ? 153.285 112.985 142.621 1.00 122.37 ? 317  LEU A O   1 
ATOM   2414 C CB  . LEU A 1 317 ? 154.139 109.862 141.963 1.00 120.20 ? 317  LEU A CB  1 
ATOM   2415 C CG  . LEU A 1 317 ? 155.282 110.343 142.865 1.00 121.18 ? 317  LEU A CG  1 
ATOM   2416 C CD1 . LEU A 1 317 ? 156.064 109.146 143.378 1.00 121.07 ? 317  LEU A CD1 1 
ATOM   2417 C CD2 . LEU A 1 317 ? 156.222 111.307 142.144 1.00 112.58 ? 317  LEU A CD2 1 
ATOM   2418 N N   . THR A 1 318 ? 153.744 112.636 140.442 1.00 111.97 ? 318  THR A N   1 
ATOM   2419 C CA  . THR A 1 318 ? 154.023 114.047 140.221 1.00 114.39 ? 318  THR A CA  1 
ATOM   2420 C C   . THR A 1 318 ? 152.811 114.898 140.559 1.00 112.35 ? 318  THR A C   1 
ATOM   2421 O O   . THR A 1 318 ? 152.960 116.000 141.099 1.00 118.04 ? 318  THR A O   1 
ATOM   2422 C CB  . THR A 1 318 ? 154.448 114.287 138.774 1.00 114.99 ? 318  THR A CB  1 
ATOM   2423 O OG1 . THR A 1 318 ? 155.496 113.375 138.422 1.00 116.33 ? 318  THR A OG1 1 
ATOM   2424 C CG2 . THR A 1 318 ? 154.940 115.715 138.593 1.00 114.86 ? 318  THR A CG2 1 
ATOM   2425 N N   . ILE A 1 319 ? 151.608 114.404 140.260 1.00 101.20 ? 319  ILE A N   1 
ATOM   2426 C CA  . ILE A 1 319 ? 150.404 115.117 140.671 1.00 103.47 ? 319  ILE A CA  1 
ATOM   2427 C C   . ILE A 1 319 ? 150.347 115.208 142.187 1.00 108.34 ? 319  ILE A C   1 
ATOM   2428 O O   . ILE A 1 319 ? 150.007 116.254 142.742 1.00 113.35 ? 319  ILE A O   1 
ATOM   2429 C CB  . ILE A 1 319 ? 149.148 114.437 140.095 1.00 108.73 ? 319  ILE A CB  1 
ATOM   2430 C CG1 . ILE A 1 319 ? 148.893 114.944 138.673 1.00 108.99 ? 319  ILE A CG1 1 
ATOM   2431 C CG2 . ILE A 1 319 ? 147.944 114.687 141.013 1.00 109.12 ? 319  ILE A CG2 1 
ATOM   2432 C CD1 . ILE A 1 319 ? 147.548 114.558 138.090 1.00 111.76 ? 319  ILE A CD1 1 
ATOM   2433 N N   . VAL A 1 320 ? 150.666 114.114 142.881 1.00 103.66 ? 320  VAL A N   1 
ATOM   2434 C CA  . VAL A 1 320 ? 150.696 114.141 144.343 1.00 102.64 ? 320  VAL A CA  1 
ATOM   2435 C C   . VAL A 1 320 ? 151.554 115.302 144.829 1.00 103.93 ? 320  VAL A C   1 
ATOM   2436 O O   . VAL A 1 320 ? 151.095 116.178 145.577 1.00 104.49 ? 320  VAL A O   1 
ATOM   2437 C CB  . VAL A 1 320 ? 151.207 112.797 144.891 1.00 103.98 ? 320  VAL A CB  1 
ATOM   2438 C CG1 . VAL A 1 320 ? 151.412 112.861 146.399 1.00 102.82 ? 320  VAL A CG1 1 
ATOM   2439 C CG2 . VAL A 1 320 ? 150.242 111.683 144.528 1.00 106.98 ? 320  VAL A CG2 1 
ATOM   2440 N N   . LEU A 1 321 ? 152.815 115.329 144.398 1.00 105.07 ? 321  LEU A N   1 
ATOM   2441 C CA  . LEU A 1 321 ? 153.746 116.328 144.917 1.00 102.51 ? 321  LEU A CA  1 
ATOM   2442 C C   . LEU A 1 321 ? 153.320 117.739 144.526 1.00 103.63 ? 321  LEU A C   1 
ATOM   2443 O O   . LEU A 1 321 ? 153.310 118.654 145.363 1.00 112.67 ? 321  LEU A O   1 
ATOM   2444 C CB  . LEU A 1 321 ? 155.158 116.033 144.413 1.00 107.28 ? 321  LEU A CB  1 
ATOM   2445 C CG  . LEU A 1 321 ? 155.811 114.729 144.886 1.00 111.64 ? 321  LEU A CG  1 
ATOM   2446 C CD1 . LEU A 1 321 ? 157.324 114.818 144.753 1.00 110.46 ? 321  LEU A CD1 1 
ATOM   2447 C CD2 . LEU A 1 321 ? 155.423 114.375 146.316 1.00 108.57 ? 321  LEU A CD2 1 
ATOM   2448 N N   . THR A 1 322 ? 152.968 117.939 143.255 1.00 110.72 ? 322  THR A N   1 
ATOM   2449 C CA  . THR A 1 322 ? 152.614 119.275 142.797 1.00 117.63 ? 322  THR A CA  1 
ATOM   2450 C C   . THR A 1 322 ? 151.336 119.774 143.453 1.00 120.04 ? 322  THR A C   1 
ATOM   2451 O O   . THR A 1 322 ? 151.227 120.964 143.758 1.00 122.13 ? 322  THR A O   1 
ATOM   2452 C CB  . THR A 1 322 ? 152.472 119.287 141.277 1.00 119.47 ? 322  THR A CB  1 
ATOM   2453 O OG1 . THR A 1 322 ? 151.612 118.218 140.865 1.00 124.82 ? 322  THR A OG1 1 
ATOM   2454 C CG2 . THR A 1 322 ? 153.832 119.120 140.626 1.00 121.24 ? 322  THR A CG2 1 
ATOM   2455 N N   . ALA A 1 323 ? 150.362 118.892 143.684 1.00 112.74 ? 323  ALA A N   1 
ATOM   2456 C CA  . ALA A 1 323 ? 149.152 119.294 144.384 1.00 110.61 ? 323  ALA A CA  1 
ATOM   2457 C C   . ALA A 1 323 ? 149.440 119.631 145.836 1.00 111.73 ? 323  ALA A C   1 
ATOM   2458 O O   . ALA A 1 323 ? 148.839 120.561 146.381 1.00 115.31 ? 323  ALA A O   1 
ATOM   2459 C CB  . ALA A 1 323 ? 148.103 118.189 144.298 1.00 108.70 ? 323  ALA A CB  1 
ATOM   2460 N N   . VAL A 1 324 ? 150.342 118.892 146.484 1.00 112.15 ? 324  VAL A N   1 
ATOM   2461 C CA  . VAL A 1 324 ? 150.736 119.258 147.841 1.00 113.08 ? 324  VAL A CA  1 
ATOM   2462 C C   . VAL A 1 324 ? 151.307 120.670 147.852 1.00 115.39 ? 324  VAL A C   1 
ATOM   2463 O O   . VAL A 1 324 ? 150.909 121.521 148.661 1.00 119.80 ? 324  VAL A O   1 
ATOM   2464 C CB  . VAL A 1 324 ? 151.743 118.239 148.403 1.00 112.06 ? 324  VAL A CB  1 
ATOM   2465 C CG1 . VAL A 1 324 ? 152.435 118.797 149.637 1.00 105.79 ? 324  VAL A CG1 1 
ATOM   2466 C CG2 . VAL A 1 324 ? 151.044 116.930 148.723 1.00 110.53 ? 324  VAL A CG2 1 
ATOM   2467 N N   . LEU A 1 325 ? 152.234 120.948 146.933 1.00 107.81 ? 325  LEU A N   1 
ATOM   2468 C CA  . LEU A 1 325 ? 152.835 122.278 146.886 1.00 101.83 ? 325  LEU A CA  1 
ATOM   2469 C C   . LEU A 1 325 ? 151.789 123.347 146.590 1.00 106.10 ? 325  LEU A C   1 
ATOM   2470 O O   . LEU A 1 325 ? 151.800 124.425 147.197 1.00 106.56 ? 325  LEU A O   1 
ATOM   2471 C CB  . LEU A 1 325 ? 153.949 122.315 145.840 1.00 100.29 ? 325  LEU A CB  1 
ATOM   2472 C CG  . LEU A 1 325 ? 155.103 121.336 146.061 1.00 100.07 ? 325  LEU A CG  1 
ATOM   2473 C CD1 . LEU A 1 325 ? 156.198 121.569 145.034 1.00 105.38 ? 325  LEU A CD1 1 
ATOM   2474 C CD2 . LEU A 1 325 ? 155.657 121.452 147.472 1.00 97.19  ? 325  LEU A CD2 1 
ATOM   2475 N N   . ALA A 1 326 ? 150.876 123.067 145.659 1.00 116.51 ? 326  ALA A N   1 
ATOM   2476 C CA  . ALA A 1 326 ? 149.850 124.042 145.308 1.00 117.35 ? 326  ALA A CA  1 
ATOM   2477 C C   . ALA A 1 326 ? 148.926 124.328 146.481 1.00 115.85 ? 326  ALA A C   1 
ATOM   2478 O O   . ALA A 1 326 ? 148.598 125.491 146.744 1.00 122.07 ? 326  ALA A O   1 
ATOM   2479 C CB  . ALA A 1 326 ? 149.044 123.537 144.114 1.00 117.16 ? 326  ALA A CB  1 
ATOM   2480 N N   . SER A 1 327 ? 148.495 123.288 147.197 1.00 114.45 ? 327  SER A N   1 
ATOM   2481 C CA  . SER A 1 327 ? 147.677 123.502 148.383 1.00 117.11 ? 327  SER A CA  1 
ATOM   2482 C C   . SER A 1 327 ? 148.431 124.327 149.412 1.00 116.11 ? 327  SER A C   1 
ATOM   2483 O O   . SER A 1 327 ? 147.844 125.177 150.091 1.00 118.77 ? 327  SER A O   1 
ATOM   2484 C CB  . SER A 1 327 ? 147.251 122.162 148.979 1.00 114.47 ? 327  SER A CB  1 
ATOM   2485 O OG  . SER A 1 327 ? 148.159 121.746 149.982 1.00 115.15 ? 327  SER A OG  1 
ATOM   2486 N N   . ILE A 1 328 ? 149.737 124.092 149.543 1.00 104.08 ? 328  ILE A N   1 
ATOM   2487 C CA  . ILE A 1 328 ? 150.540 124.930 150.427 1.00 104.84 ? 328  ILE A CA  1 
ATOM   2488 C C   . ILE A 1 328 ? 150.473 126.384 149.981 1.00 106.01 ? 328  ILE A C   1 
ATOM   2489 O O   . ILE A 1 328 ? 150.316 127.296 150.802 1.00 104.59 ? 328  ILE A O   1 
ATOM   2490 C CB  . ILE A 1 328 ? 151.993 124.423 150.475 1.00 105.67 ? 328  ILE A CB  1 
ATOM   2491 C CG1 . ILE A 1 328 ? 152.054 123.033 151.114 1.00 105.26 ? 328  ILE A CG1 1 
ATOM   2492 C CG2 . ILE A 1 328 ? 152.875 125.411 151.224 1.00 104.37 ? 328  ILE A CG2 1 
ATOM   2493 C CD1 . ILE A 1 328 ? 151.914 123.038 152.618 1.00 106.63 ? 328  ILE A CD1 1 
ATOM   2494 N N   . GLY A 1 329 ? 150.583 126.626 148.673 1.00 117.64 ? 329  GLY A N   1 
ATOM   2495 C CA  . GLY A 1 329 ? 150.631 127.989 148.172 1.00 118.34 ? 329  GLY A CA  1 
ATOM   2496 C C   . GLY A 1 329 ? 149.283 128.656 147.991 1.00 119.18 ? 329  GLY A C   1 
ATOM   2497 O O   . GLY A 1 329 ? 149.234 129.873 147.786 1.00 118.17 ? 329  GLY A O   1 
ATOM   2498 N N   . THR A 1 330 ? 148.192 127.899 148.065 1.00 120.81 ? 330  THR A N   1 
ATOM   2499 C CA  . THR A 1 330 ? 146.868 128.461 147.820 1.00 115.85 ? 330  THR A CA  1 
ATOM   2500 C C   . THR A 1 330 ? 146.475 129.403 148.952 1.00 113.32 ? 330  THR A C   1 
ATOM   2501 O O   . THR A 1 330 ? 146.763 129.133 150.123 1.00 115.01 ? 330  THR A O   1 
ATOM   2502 C CB  . THR A 1 330 ? 145.838 127.345 147.679 1.00 117.01 ? 330  THR A CB  1 
ATOM   2503 O OG1 . THR A 1 330 ? 146.434 126.217 147.027 1.00 125.61 ? 330  THR A OG1 1 
ATOM   2504 C CG2 . THR A 1 330 ? 144.642 127.825 146.870 1.00 108.41 ? 330  THR A CG2 1 
ATOM   2505 N N   . ALA A 1 331 ? 145.828 130.511 148.601 1.00 103.25 ? 331  ALA A N   1 
ATOM   2506 C CA  . ALA A 1 331 ? 145.329 131.442 149.602 1.00 103.02 ? 331  ALA A CA  1 
ATOM   2507 C C   . ALA A 1 331 ? 143.894 131.099 149.985 1.00 103.33 ? 331  ALA A C   1 
ATOM   2508 O O   . ALA A 1 331 ? 143.191 130.379 149.272 1.00 108.49 ? 331  ALA A O   1 
ATOM   2509 C CB  . ALA A 1 331 ? 145.402 132.876 149.080 1.00 103.74 ? 331  ALA A CB  1 
ATOM   2510 N N   . GLY A 1 332 ? 143.460 131.627 151.127 1.00 92.69  ? 332  GLY A N   1 
ATOM   2511 C CA  . GLY A 1 332 ? 142.135 131.333 151.640 1.00 93.34  ? 332  GLY A CA  1 
ATOM   2512 C C   . GLY A 1 332 ? 141.051 132.232 151.082 1.00 91.21  ? 332  GLY A C   1 
ATOM   2513 O O   . GLY A 1 332 ? 140.206 132.732 151.829 1.00 90.45  ? 332  GLY A O   1 
ATOM   2514 N N   . VAL A 1 333 ? 141.057 132.432 149.768 1.00 96.06  ? 333  VAL A N   1 
ATOM   2515 C CA  . VAL A 1 333 ? 140.078 133.286 149.102 1.00 97.58  ? 333  VAL A CA  1 
ATOM   2516 C C   . VAL A 1 333 ? 139.264 132.401 148.165 1.00 103.35 ? 333  VAL A C   1 
ATOM   2517 O O   . VAL A 1 333 ? 139.839 131.536 147.490 1.00 104.12 ? 333  VAL A O   1 
ATOM   2518 C CB  . VAL A 1 333 ? 140.767 134.438 148.351 1.00 101.61 ? 333  VAL A CB  1 
ATOM   2519 C CG1 . VAL A 1 333 ? 141.806 133.902 147.377 1.00 103.44 ? 333  VAL A CG1 1 
ATOM   2520 C CG2 . VAL A 1 333 ? 139.751 135.317 147.630 1.00 101.49 ? 333  VAL A CG2 1 
ATOM   2521 N N   . PRO A 1 334 ? 137.943 132.569 148.084 1.00 101.92 ? 334  PRO A N   1 
ATOM   2522 C CA  . PRO A 1 334 ? 137.141 131.645 147.273 1.00 97.08  ? 334  PRO A CA  1 
ATOM   2523 C C   . PRO A 1 334 ? 137.596 131.637 145.823 1.00 94.93  ? 334  PRO A C   1 
ATOM   2524 O O   . PRO A 1 334 ? 137.935 132.675 145.251 1.00 95.86  ? 334  PRO A O   1 
ATOM   2525 C CB  . PRO A 1 334 ? 135.715 132.190 147.418 1.00 93.12  ? 334  PRO A CB  1 
ATOM   2526 C CG  . PRO A 1 334 ? 135.882 133.598 147.864 1.00 95.38  ? 334  PRO A CG  1 
ATOM   2527 C CD  . PRO A 1 334 ? 137.104 133.596 148.719 1.00 98.03  ? 334  PRO A CD  1 
ATOM   2528 N N   . GLY A 1 335 ? 137.599 130.445 145.229 1.00 94.92  ? 335  GLY A N   1 
ATOM   2529 C CA  . GLY A 1 335 ? 138.062 130.264 143.872 1.00 96.27  ? 335  GLY A CA  1 
ATOM   2530 C C   . GLY A 1 335 ? 139.559 130.119 143.724 1.00 99.74  ? 335  GLY A C   1 
ATOM   2531 O O   . GLY A 1 335 ? 140.034 129.905 142.602 1.00 100.55 ? 335  GLY A O   1 
ATOM   2532 N N   . ALA A 1 336 ? 140.323 130.224 144.814 1.00 98.09  ? 336  ALA A N   1 
ATOM   2533 C CA  . ALA A 1 336 ? 141.772 130.103 144.711 1.00 97.77  ? 336  ALA A CA  1 
ATOM   2534 C C   . ALA A 1 336 ? 142.188 128.712 144.257 1.00 102.57 ? 336  ALA A C   1 
ATOM   2535 O O   . ALA A 1 336 ? 143.116 128.575 143.451 1.00 105.43 ? 336  ALA A O   1 
ATOM   2536 C CB  . ALA A 1 336 ? 142.424 130.433 146.053 1.00 94.19  ? 336  ALA A CB  1 
ATOM   2537 N N   . GLY A 1 337 ? 141.518 127.672 144.756 1.00 105.15 ? 337  GLY A N   1 
ATOM   2538 C CA  . GLY A 1 337 ? 141.902 126.319 144.394 1.00 103.33 ? 337  GLY A CA  1 
ATOM   2539 C C   . GLY A 1 337 ? 141.874 126.077 142.900 1.00 100.30 ? 337  GLY A C   1 
ATOM   2540 O O   . GLY A 1 337 ? 142.769 125.425 142.356 1.00 103.01 ? 337  GLY A O   1 
ATOM   2541 N N   . LEU A 1 338 ? 140.855 126.596 142.215 1.00 100.21 ? 338  LEU A N   1 
ATOM   2542 C CA  . LEU A 1 338 ? 140.789 126.438 140.767 1.00 104.54 ? 338  LEU A CA  1 
ATOM   2543 C C   . LEU A 1 338 ? 141.959 127.134 140.085 1.00 107.10 ? 338  LEU A C   1 
ATOM   2544 O O   . LEU A 1 338 ? 142.545 126.594 139.140 1.00 106.91 ? 338  LEU A O   1 
ATOM   2545 C CB  . LEU A 1 338 ? 139.463 126.985 140.243 1.00 105.49 ? 338  LEU A CB  1 
ATOM   2546 C CG  . LEU A 1 338 ? 139.243 126.891 138.732 1.00 100.29 ? 338  LEU A CG  1 
ATOM   2547 C CD1 . LEU A 1 338 ? 138.986 125.452 138.326 1.00 101.00 ? 338  LEU A CD1 1 
ATOM   2548 C CD2 . LEU A 1 338 ? 138.092 127.784 138.305 1.00 97.80  ? 338  LEU A CD2 1 
ATOM   2549 N N   . VAL A 1 339 ? 142.314 128.332 140.549 1.00 111.98 ? 339  VAL A N   1 
ATOM   2550 C CA  . VAL A 1 339 ? 143.388 129.083 139.906 1.00 109.68 ? 339  VAL A CA  1 
ATOM   2551 C C   . VAL A 1 339 ? 144.697 128.311 139.995 1.00 107.83 ? 339  VAL A C   1 
ATOM   2552 O O   . VAL A 1 339 ? 145.428 128.176 139.007 1.00 105.92 ? 339  VAL A O   1 
ATOM   2553 C CB  . VAL A 1 339 ? 143.518 130.481 140.535 1.00 111.48 ? 339  VAL A CB  1 
ATOM   2554 C CG1 . VAL A 1 339 ? 144.677 131.237 139.907 1.00 112.08 ? 339  VAL A CG1 1 
ATOM   2555 C CG2 . VAL A 1 339 ? 142.221 131.266 140.376 1.00 107.61 ? 339  VAL A CG2 1 
ATOM   2556 N N   . MET A 1 340 ? 145.007 127.779 141.178 1.00 109.21 ? 340  MET A N   1 
ATOM   2557 C CA  . MET A 1 340 ? 146.239 127.019 141.353 1.00 108.44 ? 340  MET A CA  1 
ATOM   2558 C C   . MET A 1 340 ? 146.228 125.705 140.589 1.00 109.06 ? 340  MET A C   1 
ATOM   2559 O O   . MET A 1 340 ? 147.285 125.080 140.456 1.00 110.81 ? 340  MET A O   1 
ATOM   2560 C CB  . MET A 1 340 ? 146.484 126.740 142.833 1.00 107.99 ? 340  MET A CB  1 
ATOM   2561 C CG  . MET A 1 340 ? 146.836 127.955 143.704 1.00 114.00 ? 340  MET A CG  1 
ATOM   2562 S SD  . MET A 1 340 ? 148.239 128.982 143.193 1.00 123.29 ? 340  MET A SD  1 
ATOM   2563 C CE  . MET A 1 340 ? 147.563 129.980 141.863 1.00 112.41 ? 340  MET A CE  1 
ATOM   2564 N N   . LEU A 1 341 ? 145.072 125.269 140.085 1.00 109.49 ? 341  LEU A N   1 
ATOM   2565 C CA  . LEU A 1 341 ? 145.031 124.042 139.300 1.00 110.52 ? 341  LEU A CA  1 
ATOM   2566 C C   . LEU A 1 341 ? 145.909 124.129 138.061 1.00 112.43 ? 341  LEU A C   1 
ATOM   2567 O O   . LEU A 1 341 ? 146.333 123.090 137.544 1.00 113.86 ? 341  LEU A O   1 
ATOM   2568 C CB  . LEU A 1 341 ? 143.589 123.726 138.899 1.00 108.54 ? 341  LEU A CB  1 
ATOM   2569 C CG  . LEU A 1 341 ? 143.324 122.342 138.299 1.00 106.58 ? 341  LEU A CG  1 
ATOM   2570 C CD1 . LEU A 1 341 ? 144.057 121.258 139.065 1.00 111.38 ? 341  LEU A CD1 1 
ATOM   2571 C CD2 . LEU A 1 341 ? 141.835 122.052 138.273 1.00 107.39 ? 341  LEU A CD2 1 
ATOM   2572 N N   . THR A 1 342 ? 146.194 125.340 137.578 1.00 116.63 ? 342  THR A N   1 
ATOM   2573 C CA  . THR A 1 342 ? 147.124 125.489 136.466 1.00 114.36 ? 342  THR A CA  1 
ATOM   2574 C C   . THR A 1 342 ? 148.501 124.958 136.837 1.00 114.35 ? 342  THR A C   1 
ATOM   2575 O O   . THR A 1 342 ? 149.153 124.279 136.034 1.00 112.73 ? 342  THR A O   1 
ATOM   2576 C CB  . THR A 1 342 ? 147.218 126.956 136.052 1.00 117.64 ? 342  THR A CB  1 
ATOM   2577 O OG1 . THR A 1 342 ? 147.566 127.753 137.190 1.00 120.54 ? 342  THR A OG1 1 
ATOM   2578 C CG2 . THR A 1 342 ? 145.898 127.435 135.484 1.00 114.82 ? 342  THR A CG2 1 
ATOM   2579 N N   . MET A 1 343 ? 148.960 125.255 138.054 1.00 125.21 ? 343  MET A N   1 
ATOM   2580 C CA  . MET A 1 343 ? 150.267 124.777 138.487 1.00 124.59 ? 343  MET A CA  1 
ATOM   2581 C C   . MET A 1 343 ? 150.325 123.256 138.485 1.00 126.05 ? 343  MET A C   1 
ATOM   2582 O O   . MET A 1 343 ? 151.371 122.675 138.174 1.00 128.23 ? 343  MET A O   1 
ATOM   2583 C CB  . MET A 1 343 ? 150.584 125.337 139.878 1.00 124.60 ? 343  MET A CB  1 
ATOM   2584 C CG  . MET A 1 343 ? 151.679 124.610 140.661 1.00 123.70 ? 343  MET A CG  1 
ATOM   2585 S SD  . MET A 1 343 ? 151.671 125.050 142.408 1.00 128.94 ? 343  MET A SD  1 
ATOM   2586 C CE  . MET A 1 343 ? 152.588 126.585 142.381 1.00 125.22 ? 343  MET A CE  1 
ATOM   2587 N N   . VAL A 1 344 ? 149.221 122.594 138.830 1.00 115.25 ? 344  VAL A N   1 
ATOM   2588 C CA  . VAL A 1 344 ? 149.202 121.134 138.844 1.00 114.13 ? 344  VAL A CA  1 
ATOM   2589 C C   . VAL A 1 344 ? 149.135 120.591 137.422 1.00 115.89 ? 344  VAL A C   1 
ATOM   2590 O O   . VAL A 1 344 ? 149.910 119.708 137.038 1.00 115.07 ? 344  VAL A O   1 
ATOM   2591 C CB  . VAL A 1 344 ? 148.029 120.620 139.695 1.00 111.42 ? 344  VAL A CB  1 
ATOM   2592 C CG1 . VAL A 1 344 ? 147.889 119.113 139.550 1.00 113.20 ? 344  VAL A CG1 1 
ATOM   2593 C CG2 . VAL A 1 344 ? 148.223 120.998 141.153 1.00 115.92 ? 344  VAL A CG2 1 
ATOM   2594 N N   . LEU A 1 345 ? 148.208 121.116 136.619 1.00 110.48 ? 345  LEU A N   1 
ATOM   2595 C CA  . LEU A 1 345 ? 148.025 120.593 135.270 1.00 107.25 ? 345  LEU A CA  1 
ATOM   2596 C C   . LEU A 1 345 ? 149.278 120.781 134.427 1.00 106.99 ? 345  LEU A C   1 
ATOM   2597 O O   . LEU A 1 345 ? 149.685 119.872 133.695 1.00 104.22 ? 345  LEU A O   1 
ATOM   2598 C CB  . LEU A 1 345 ? 146.828 121.270 134.606 1.00 104.73 ? 345  LEU A CB  1 
ATOM   2599 C CG  . LEU A 1 345 ? 145.468 120.925 135.210 1.00 103.61 ? 345  LEU A CG  1 
ATOM   2600 C CD1 . LEU A 1 345 ? 144.399 121.868 134.690 1.00 107.82 ? 345  LEU A CD1 1 
ATOM   2601 C CD2 . LEU A 1 345 ? 145.104 119.483 134.906 1.00 103.52 ? 345  LEU A CD2 1 
ATOM   2602 N N   . THR A 1 346 ? 149.907 121.954 134.517 1.00 113.37 ? 346  THR A N   1 
ATOM   2603 C CA  . THR A 1 346 ? 151.093 122.210 133.710 1.00 112.36 ? 346  THR A CA  1 
ATOM   2604 C C   . THR A 1 346 ? 152.192 121.198 133.997 1.00 116.07 ? 346  THR A C   1 
ATOM   2605 O O   . THR A 1 346 ? 152.947 120.829 133.090 1.00 118.92 ? 346  THR A O   1 
ATOM   2606 C CB  . THR A 1 346 ? 151.609 123.626 133.963 1.00 113.62 ? 346  THR A CB  1 
ATOM   2607 O OG1 . THR A 1 346 ? 151.678 123.868 135.374 1.00 117.22 ? 346  THR A OG1 1 
ATOM   2608 C CG2 . THR A 1 346 ? 150.690 124.650 133.318 1.00 113.44 ? 346  THR A CG2 1 
ATOM   2609 N N   . SER A 1 347 ? 152.296 120.735 135.243 1.00 117.75 ? 347  SER A N   1 
ATOM   2610 C CA  . SER A 1 347 ? 153.347 119.785 135.590 1.00 116.83 ? 347  SER A CA  1 
ATOM   2611 C C   . SER A 1 347 ? 153.214 118.501 134.783 1.00 116.10 ? 347  SER A C   1 
ATOM   2612 O O   . SER A 1 347 ? 154.206 117.975 134.265 1.00 115.69 ? 347  SER A O   1 
ATOM   2613 C CB  . SER A 1 347 ? 153.302 119.483 137.086 1.00 115.43 ? 347  SER A CB  1 
ATOM   2614 O OG  . SER A 1 347 ? 154.333 118.583 137.449 1.00 120.16 ? 347  SER A OG  1 
ATOM   2615 N N   . VAL A 1 348 ? 151.994 117.978 134.667 1.00 115.39 ? 348  VAL A N   1 
ATOM   2616 C CA  . VAL A 1 348 ? 151.788 116.762 133.890 1.00 116.61 ? 348  VAL A CA  1 
ATOM   2617 C C   . VAL A 1 348 ? 151.669 117.080 132.404 1.00 121.47 ? 348  VAL A C   1 
ATOM   2618 O O   . VAL A 1 348 ? 151.797 116.183 131.563 1.00 116.96 ? 348  VAL A O   1 
ATOM   2619 C CB  . VAL A 1 348 ? 150.548 116.013 134.406 1.00 119.39 ? 348  VAL A CB  1 
ATOM   2620 C CG1 . VAL A 1 348 ? 150.278 114.775 133.563 1.00 121.52 ? 348  VAL A CG1 1 
ATOM   2621 C CG2 . VAL A 1 348 ? 150.735 115.640 135.864 1.00 118.75 ? 348  VAL A CG2 1 
ATOM   2622 N N   . GLY A 1 349 ? 151.435 118.341 132.054 1.00 119.01 ? 349  GLY A N   1 
ATOM   2623 C CA  . GLY A 1 349 ? 151.274 118.715 130.667 1.00 112.98 ? 349  GLY A CA  1 
ATOM   2624 C C   . GLY A 1 349 ? 149.864 118.592 130.143 1.00 111.71 ? 349  GLY A C   1 
ATOM   2625 O O   . GLY A 1 349 ? 149.653 118.713 128.931 1.00 110.16 ? 349  GLY A O   1 
ATOM   2626 N N   . LEU A 1 350 ? 148.890 118.353 131.013 1.00 109.01 ? 350  LEU A N   1 
ATOM   2627 C CA  . LEU A 1 350 ? 147.512 118.273 130.566 1.00 105.08 ? 350  LEU A CA  1 
ATOM   2628 C C   . LEU A 1 350 ? 147.049 119.631 130.043 1.00 107.52 ? 350  LEU A C   1 
ATOM   2629 O O   . LEU A 1 350 ? 147.519 120.674 130.504 1.00 108.92 ? 350  LEU A O   1 
ATOM   2630 C CB  . LEU A 1 350 ? 146.606 117.828 131.706 1.00 105.74 ? 350  LEU A CB  1 
ATOM   2631 C CG  . LEU A 1 350 ? 146.894 116.441 132.277 1.00 110.77 ? 350  LEU A CG  1 
ATOM   2632 C CD1 . LEU A 1 350 ? 146.069 116.197 133.528 1.00 114.01 ? 350  LEU A CD1 1 
ATOM   2633 C CD2 . LEU A 1 350 ? 146.619 115.369 131.237 1.00 111.96 ? 350  LEU A CD2 1 
ATOM   2634 N N   . PRO A 1 351 ? 146.130 119.647 129.079 1.00 115.63 ? 351  PRO A N   1 
ATOM   2635 C CA  . PRO A 1 351 ? 145.677 120.929 128.525 1.00 119.21 ? 351  PRO A CA  1 
ATOM   2636 C C   . PRO A 1 351 ? 144.972 121.762 129.584 1.00 119.86 ? 351  PRO A C   1 
ATOM   2637 O O   . PRO A 1 351 ? 144.156 121.251 130.353 1.00 128.62 ? 351  PRO A O   1 
ATOM   2638 C CB  . PRO A 1 351 ? 144.721 120.512 127.402 1.00 117.23 ? 351  PRO A CB  1 
ATOM   2639 C CG  . PRO A 1 351 ? 144.230 119.168 127.811 1.00 115.15 ? 351  PRO A CG  1 
ATOM   2640 C CD  . PRO A 1 351 ? 145.377 118.510 128.521 1.00 116.31 ? 351  PRO A CD  1 
ATOM   2641 N N   . LEU A 1 352 ? 145.292 123.056 129.618 1.00 115.75 ? 352  LEU A N   1 
ATOM   2642 C CA  . LEU A 1 352 ? 144.604 123.961 130.528 1.00 116.37 ? 352  LEU A CA  1 
ATOM   2643 C C   . LEU A 1 352 ? 143.178 124.251 130.087 1.00 119.72 ? 352  LEU A C   1 
ATOM   2644 O O   . LEU A 1 352 ? 142.416 124.836 130.864 1.00 115.37 ? 352  LEU A O   1 
ATOM   2645 C CB  . LEU A 1 352 ? 145.378 125.274 130.656 1.00 114.26 ? 352  LEU A CB  1 
ATOM   2646 C CG  . LEU A 1 352 ? 146.741 125.210 131.349 1.00 116.15 ? 352  LEU A CG  1 
ATOM   2647 C CD1 . LEU A 1 352 ? 147.247 126.614 131.633 1.00 117.62 ? 352  LEU A CD1 1 
ATOM   2648 C CD2 . LEU A 1 352 ? 146.679 124.400 132.633 1.00 116.88 ? 352  LEU A CD2 1 
ATOM   2649 N N   . GLU A 1 353 ? 142.799 123.859 128.869 1.00 125.09 ? 353  GLU A N   1 
ATOM   2650 C CA  . GLU A 1 353 ? 141.429 124.071 128.420 1.00 122.83 ? 353  GLU A CA  1 
ATOM   2651 C C   . GLU A 1 353 ? 140.432 123.402 129.353 1.00 119.12 ? 353  GLU A C   1 
ATOM   2652 O O   . GLU A 1 353 ? 139.286 123.850 129.465 1.00 118.91 ? 353  GLU A O   1 
ATOM   2653 C CB  . GLU A 1 353 ? 141.254 123.540 126.997 1.00 123.00 ? 353  GLU A CB  1 
ATOM   2654 C CG  . GLU A 1 353 ? 141.683 124.514 125.912 1.00 122.06 ? 353  GLU A CG  1 
ATOM   2655 C CD  . GLU A 1 353 ? 143.118 124.972 126.073 1.00 124.97 ? 353  GLU A CD  1 
ATOM   2656 O OE1 . GLU A 1 353 ? 143.961 124.152 126.494 1.00 123.34 ? 353  GLU A OE1 1 
ATOM   2657 O OE2 . GLU A 1 353 ? 143.405 126.151 125.778 1.00 127.94 ? 353  GLU A OE2 1 
ATOM   2658 N N   . GLY A 1 354 ? 140.849 122.334 130.035 1.00 110.06 ? 354  GLY A N   1 
ATOM   2659 C CA  . GLY A 1 354 ? 139.951 121.659 130.954 1.00 114.09 ? 354  GLY A CA  1 
ATOM   2660 C C   . GLY A 1 354 ? 139.471 122.554 132.078 1.00 115.86 ? 354  GLY A C   1 
ATOM   2661 O O   . GLY A 1 354 ? 138.382 122.347 132.617 1.00 118.17 ? 354  GLY A O   1 
ATOM   2662 N N   . ILE A 1 355 ? 140.267 123.561 132.442 1.00 104.58 ? 355  ILE A N   1 
ATOM   2663 C CA  . ILE A 1 355 ? 139.865 124.464 133.516 1.00 104.69 ? 355  ILE A CA  1 
ATOM   2664 C C   . ILE A 1 355 ? 138.547 125.140 133.171 1.00 111.50 ? 355  ILE A C   1 
ATOM   2665 O O   . ILE A 1 355 ? 137.689 125.341 134.038 1.00 114.15 ? 355  ILE A O   1 
ATOM   2666 C CB  . ILE A 1 355 ? 140.977 125.493 133.793 1.00 99.28  ? 355  ILE A CB  1 
ATOM   2667 C CG1 . ILE A 1 355 ? 142.073 124.848 134.643 1.00 102.24 ? 355  ILE A CG1 1 
ATOM   2668 C CG2 . ILE A 1 355 ? 140.399 126.731 134.476 1.00 100.16 ? 355  ILE A CG2 1 
ATOM   2669 C CD1 . ILE A 1 355 ? 143.218 125.769 134.985 1.00 107.33 ? 355  ILE A CD1 1 
ATOM   2670 N N   . ALA A 1 356 ? 138.364 125.505 131.900 1.00 111.54 ? 356  ALA A N   1 
ATOM   2671 C CA  . ALA A 1 356 ? 137.098 126.098 131.485 1.00 109.39 ? 356  ALA A CA  1 
ATOM   2672 C C   . ALA A 1 356 ? 135.923 125.196 131.833 1.00 105.66 ? 356  ALA A C   1 
ATOM   2673 O O   . ALA A 1 356 ? 134.831 125.688 132.138 1.00 104.88 ? 356  ALA A O   1 
ATOM   2674 C CB  . ALA A 1 356 ? 137.122 126.384 129.985 1.00 108.53 ? 356  ALA A CB  1 
ATOM   2675 N N   . LEU A 1 357 ? 136.124 123.877 131.797 1.00 103.49 ? 357  LEU A N   1 
ATOM   2676 C CA  . LEU A 1 357 ? 135.052 122.959 132.162 1.00 105.34 ? 357  LEU A CA  1 
ATOM   2677 C C   . LEU A 1 357 ? 134.671 123.112 133.629 1.00 105.34 ? 357  LEU A C   1 
ATOM   2678 O O   . LEU A 1 357 ? 133.486 123.055 133.978 1.00 112.97 ? 357  LEU A O   1 
ATOM   2679 C CB  . LEU A 1 357 ? 135.473 121.519 131.870 1.00 103.03 ? 357  LEU A CB  1 
ATOM   2680 C CG  . LEU A 1 357 ? 135.888 121.210 130.431 1.00 106.57 ? 357  LEU A CG  1 
ATOM   2681 C CD1 . LEU A 1 357 ? 136.244 119.741 130.287 1.00 107.43 ? 357  LEU A CD1 1 
ATOM   2682 C CD2 . LEU A 1 357 ? 134.788 121.592 129.454 1.00 108.16 ? 357  LEU A CD2 1 
ATOM   2683 N N   . ILE A 1 358 ? 135.659 123.305 134.502 1.00 104.40 ? 358  ILE A N   1 
ATOM   2684 C CA  . ILE A 1 358 ? 135.389 123.342 135.935 1.00 103.82 ? 358  ILE A CA  1 
ATOM   2685 C C   . ILE A 1 358 ? 134.976 124.739 136.379 1.00 110.87 ? 358  ILE A C   1 
ATOM   2686 O O   . ILE A 1 358 ? 134.298 124.901 137.399 1.00 117.85 ? 358  ILE A O   1 
ATOM   2687 C CB  . ILE A 1 358 ? 136.619 122.851 136.719 1.00 104.14 ? 358  ILE A CB  1 
ATOM   2688 C CG1 . ILE A 1 358 ? 137.248 121.635 136.037 1.00 109.21 ? 358  ILE A CG1 1 
ATOM   2689 C CG2 . ILE A 1 358 ? 136.236 122.526 138.152 1.00 105.20 ? 358  ILE A CG2 1 
ATOM   2690 C CD1 . ILE A 1 358 ? 136.284 120.502 135.793 1.00 108.02 ? 358  ILE A CD1 1 
ATOM   2691 N N   . ALA A 1 359 ? 135.371 125.767 135.626 1.00 114.79 ? 359  ALA A N   1 
ATOM   2692 C CA  . ALA A 1 359 ? 135.156 127.139 136.072 1.00 112.72 ? 359  ALA A CA  1 
ATOM   2693 C C   . ALA A 1 359 ? 133.690 127.441 136.344 1.00 111.01 ? 359  ALA A C   1 
ATOM   2694 O O   . ALA A 1 359 ? 133.391 128.309 137.170 1.00 108.92 ? 359  ALA A O   1 
ATOM   2695 C CB  . ALA A 1 359 ? 135.700 128.117 135.030 1.00 116.14 ? 359  ALA A CB  1 
ATOM   2696 N N   . GLY A 1 360 ? 132.771 126.751 135.676 1.00 107.13 ? 360  GLY A N   1 
ATOM   2697 C CA  . GLY A 1 360 ? 131.359 126.999 135.878 1.00 110.28 ? 360  GLY A CA  1 
ATOM   2698 C C   . GLY A 1 360 ? 130.873 126.564 137.243 1.00 106.81 ? 360  GLY A C   1 
ATOM   2699 O O   . GLY A 1 360 ? 130.421 127.385 138.045 1.00 108.83 ? 360  GLY A O   1 
ATOM   2700 N N   . ILE A 1 361 ? 130.983 125.265 137.525 1.00 97.18  ? 361  ILE A N   1 
ATOM   2701 C CA  . ILE A 1 361 ? 130.462 124.693 138.758 1.00 97.76  ? 361  ILE A CA  1 
ATOM   2702 C C   . ILE A 1 361 ? 131.405 124.879 139.936 1.00 101.92 ? 361  ILE A C   1 
ATOM   2703 O O   . ILE A 1 361 ? 131.166 124.308 141.004 1.00 103.14 ? 361  ILE A O   1 
ATOM   2704 C CB  . ILE A 1 361 ? 130.143 123.196 138.535 1.00 98.43  ? 361  ILE A CB  1 
ATOM   2705 C CG1 . ILE A 1 361 ? 131.402 122.328 138.657 1.00 100.63 ? 361  ILE A CG1 1 
ATOM   2706 C CG2 . ILE A 1 361 ? 129.504 122.986 137.177 1.00 102.72 ? 361  ILE A CG2 1 
ATOM   2707 C CD1 . ILE A 1 361 ? 131.108 120.855 138.690 1.00 103.54 ? 361  ILE A CD1 1 
ATOM   2708 N N   . ASP A 1 362 ? 132.469 125.666 139.770 1.00 102.19 ? 362  ASP A N   1 
ATOM   2709 C CA  . ASP A 1 362 ? 133.558 125.658 140.740 1.00 99.38  ? 362  ASP A CA  1 
ATOM   2710 C C   . ASP A 1 362 ? 133.086 125.903 142.165 1.00 98.79  ? 362  ASP A C   1 
ATOM   2711 O O   . ASP A 1 362 ? 133.630 125.309 143.099 1.00 108.60 ? 362  ASP A O   1 
ATOM   2712 C CB  . ASP A 1 362 ? 134.603 126.705 140.367 1.00 102.10 ? 362  ASP A CB  1 
ATOM   2713 C CG  . ASP A 1 362 ? 135.817 126.643 141.263 1.00 101.02 ? 362  ASP A CG  1 
ATOM   2714 O OD1 . ASP A 1 362 ? 136.618 125.701 141.105 1.00 101.66 ? 362  ASP A OD1 1 
ATOM   2715 O OD2 . ASP A 1 362 ? 135.965 127.530 142.129 1.00 102.13 ? 362  ASP A OD2 1 
ATOM   2716 N N   . ARG A 1 363 ? 132.093 126.771 142.362 1.00 92.52  ? 363  ARG A N   1 
ATOM   2717 C CA  . ARG A 1 363 ? 131.713 127.141 143.722 1.00 100.79 ? 363  ARG A CA  1 
ATOM   2718 C C   . ARG A 1 363 ? 131.184 125.943 144.501 1.00 106.44 ? 363  ARG A C   1 
ATOM   2719 O O   . ARG A 1 363 ? 131.415 125.827 145.712 1.00 107.55 ? 363  ARG A O   1 
ATOM   2720 C CB  . ARG A 1 363 ? 130.673 128.259 143.694 1.00 94.18  ? 363  ARG A CB  1 
ATOM   2721 C CG  . ARG A 1 363 ? 130.303 128.761 145.075 1.00 98.09  ? 363  ARG A CG  1 
ATOM   2722 C CD  . ARG A 1 363 ? 129.549 130.072 145.017 1.00 105.57 ? 363  ARG A CD  1 
ATOM   2723 N NE  . ARG A 1 363 ? 129.234 130.564 146.353 1.00 106.21 ? 363  ARG A NE  1 
ATOM   2724 C CZ  . ARG A 1 363 ? 130.051 131.301 147.093 1.00 102.81 ? 363  ARG A CZ  1 
ATOM   2725 N NH1 . ARG A 1 363 ? 131.248 131.657 146.657 1.00 101.09 ? 363  ARG A NH1 1 
ATOM   2726 N NH2 . ARG A 1 363 ? 129.658 131.689 148.302 1.00 101.74 ? 363  ARG A NH2 1 
ATOM   2727 N N   . ILE A 1 364 ? 130.455 125.049 143.831 1.00 101.25 ? 364  ILE A N   1 
ATOM   2728 C CA  . ILE A 1 364 ? 129.888 123.902 144.530 1.00 102.42 ? 364  ILE A CA  1 
ATOM   2729 C C   . ILE A 1 364 ? 130.993 123.008 145.077 1.00 105.65 ? 364  ILE A C   1 
ATOM   2730 O O   . ILE A 1 364 ? 130.848 122.420 146.156 1.00 109.75 ? 364  ILE A O   1 
ATOM   2731 C CB  . ILE A 1 364 ? 128.938 123.134 143.596 1.00 95.62  ? 364  ILE A CB  1 
ATOM   2732 C CG1 . ILE A 1 364 ? 127.631 123.911 143.426 1.00 97.14  ? 364  ILE A CG1 1 
ATOM   2733 C CG2 . ILE A 1 364 ? 128.648 121.751 144.148 1.00 95.14  ? 364  ILE A CG2 1 
ATOM   2734 C CD1 . ILE A 1 364 ? 127.185 124.052 141.990 1.00 99.02  ? 364  ILE A CD1 1 
ATOM   2735 N N   . LEU A 1 365 ? 132.103 122.877 144.350 1.00 101.20 ? 365  LEU A N   1 
ATOM   2736 C CA  . LEU A 1 365 ? 133.250 122.131 144.855 1.00 99.67  ? 365  LEU A CA  1 
ATOM   2737 C C   . LEU A 1 365 ? 134.027 122.932 145.891 1.00 109.40 ? 365  LEU A C   1 
ATOM   2738 O O   . LEU A 1 365 ? 134.602 122.353 146.828 1.00 117.03 ? 365  LEU A O   1 
ATOM   2739 C CB  . LEU A 1 365 ? 134.169 121.752 143.694 1.00 101.04 ? 365  LEU A CB  1 
ATOM   2740 C CG  . LEU A 1 365 ? 133.692 120.634 142.765 1.00 106.32 ? 365  LEU A CG  1 
ATOM   2741 C CD1 . LEU A 1 365 ? 132.379 120.998 142.094 1.00 106.41 ? 365  LEU A CD1 1 
ATOM   2742 C CD2 . LEU A 1 365 ? 134.749 120.337 141.717 1.00 109.79 ? 365  LEU A CD2 1 
ATOM   2743 N N   . ASP A 1 366 ? 134.061 124.255 145.722 1.00 111.17 ? 366  ASP A N   1 
ATOM   2744 C CA  . ASP A 1 366 ? 134.744 125.117 146.676 1.00 106.62 ? 366  ASP A CA  1 
ATOM   2745 C C   . ASP A 1 366 ? 134.133 124.972 148.057 1.00 110.87 ? 366  ASP A C   1 
ATOM   2746 O O   . ASP A 1 366 ? 134.850 124.943 149.061 1.00 117.04 ? 366  ASP A O   1 
ATOM   2747 C CB  . ASP A 1 366 ? 134.673 126.572 146.210 1.00 107.04 ? 366  ASP A CB  1 
ATOM   2748 C CG  . ASP A 1 366 ? 135.885 127.381 146.627 1.00 115.76 ? 366  ASP A CG  1 
ATOM   2749 O OD1 . ASP A 1 366 ? 136.832 126.798 147.196 1.00 114.67 ? 366  ASP A OD1 1 
ATOM   2750 O OD2 . ASP A 1 366 ? 135.893 128.605 146.382 1.00 119.36 ? 366  ASP A OD2 1 
ATOM   2751 N N   . MET A 1 367 ? 132.806 124.878 148.125 1.00 98.28  ? 367  MET A N   1 
ATOM   2752 C CA  . MET A 1 367 ? 132.148 124.694 149.414 1.00 103.45 ? 367  MET A CA  1 
ATOM   2753 C C   . MET A 1 367 ? 132.718 123.490 150.155 1.00 104.20 ? 367  MET A C   1 
ATOM   2754 O O   . MET A 1 367 ? 133.157 123.605 151.307 1.00 113.20 ? 367  MET A O   1 
ATOM   2755 C CB  . MET A 1 367 ? 130.642 124.522 149.207 1.00 97.79  ? 367  MET A CB  1 
ATOM   2756 C CG  . MET A 1 367 ? 129.955 125.695 148.526 1.00 100.00 ? 367  MET A CG  1 
ATOM   2757 S SD  . MET A 1 367 ? 128.406 125.217 147.738 1.00 115.78 ? 367  MET A SD  1 
ATOM   2758 C CE  . MET A 1 367 ? 127.212 126.113 148.723 1.00 107.02 ? 367  MET A CE  1 
ATOM   2759 N N   . ALA A 1 368 ? 132.747 122.330 149.499 1.00 88.57  ? 368  ALA A N   1 
ATOM   2760 C CA  . ALA A 1 368 ? 133.177 121.106 150.166 1.00 89.07  ? 368  ALA A CA  1 
ATOM   2761 C C   . ALA A 1 368 ? 134.654 121.166 150.532 1.00 94.11  ? 368  ALA A C   1 
ATOM   2762 O O   . ALA A 1 368 ? 135.049 120.796 151.648 1.00 111.03 ? 368  ALA A O   1 
ATOM   2763 C CB  . ALA A 1 368 ? 132.890 119.898 149.274 1.00 96.08  ? 368  ALA A CB  1 
ATOM   2764 N N   . ARG A 1 369 ? 135.497 121.619 149.601 1.00 91.99  ? 369  ARG A N   1 
ATOM   2765 C CA  . ARG A 1 369 ? 136.926 121.627 149.895 1.00 97.47  ? 369  ARG A CA  1 
ATOM   2766 C C   . ARG A 1 369 ? 137.250 122.624 150.999 1.00 102.91 ? 369  ARG A C   1 
ATOM   2767 O O   . ARG A 1 369 ? 138.133 122.374 151.827 1.00 110.29 ? 369  ARG A O   1 
ATOM   2768 C CB  . ARG A 1 369 ? 137.739 121.918 148.635 1.00 93.75  ? 369  ARG A CB  1 
ATOM   2769 C CG  . ARG A 1 369 ? 137.509 123.272 148.026 1.00 100.10 ? 369  ARG A CG  1 
ATOM   2770 C CD  . ARG A 1 369 ? 138.224 123.369 146.689 1.00 93.84  ? 369  ARG A CD  1 
ATOM   2771 N NE  . ARG A 1 369 ? 138.090 124.686 146.077 1.00 91.85  ? 369  ARG A NE  1 
ATOM   2772 C CZ  . ARG A 1 369 ? 137.618 124.913 144.857 1.00 98.44  ? 369  ARG A CZ  1 
ATOM   2773 N NH1 . ARG A 1 369 ? 137.218 123.927 144.069 1.00 99.80  ? 369  ARG A NH1 1 
ATOM   2774 N NH2 . ARG A 1 369 ? 137.545 126.164 144.414 1.00 107.16 ? 369  ARG A NH2 1 
ATOM   2775 N N   . THR A 1 370 ? 136.534 123.750 151.049 1.00 93.37  ? 370  THR A N   1 
ATOM   2776 C CA  . THR A 1 370 ? 136.732 124.699 152.138 1.00 92.64  ? 370  THR A CA  1 
ATOM   2777 C C   . THR A 1 370 ? 136.278 124.109 153.465 1.00 97.82  ? 370  THR A C   1 
ATOM   2778 O O   . THR A 1 370 ? 136.919 124.329 154.501 1.00 104.30 ? 370  THR A O   1 
ATOM   2779 C CB  . THR A 1 370 ? 135.981 125.996 151.840 1.00 96.09  ? 370  THR A CB  1 
ATOM   2780 O OG1 . THR A 1 370 ? 136.766 126.811 150.962 1.00 110.64 ? 370  THR A OG1 1 
ATOM   2781 C CG2 . THR A 1 370 ? 135.700 126.768 153.119 1.00 102.28 ? 370  THR A CG2 1 
ATOM   2782 N N   . THR A 1 371 ? 135.168 123.369 153.463 1.00 95.57  ? 371  THR A N   1 
ATOM   2783 C CA  . THR A 1 371 ? 134.742 122.713 154.695 1.00 89.90  ? 371  THR A CA  1 
ATOM   2784 C C   . THR A 1 371 ? 135.816 121.760 155.200 1.00 84.20  ? 371  THR A C   1 
ATOM   2785 O O   . THR A 1 371 ? 136.142 121.754 156.394 1.00 97.54  ? 371  THR A O   1 
ATOM   2786 C CB  . THR A 1 371 ? 133.432 121.963 154.471 1.00 93.84  ? 371  THR A CB  1 
ATOM   2787 O OG1 . THR A 1 371 ? 132.435 122.869 153.985 1.00 106.58 ? 371  THR A OG1 1 
ATOM   2788 C CG2 . THR A 1 371 ? 132.952 121.333 155.765 1.00 89.82  ? 371  THR A CG2 1 
ATOM   2789 N N   . VAL A 1 372 ? 136.383 120.955 154.302 1.00 78.45  ? 372  VAL A N   1 
ATOM   2790 C CA  . VAL A 1 372 ? 137.437 120.029 154.707 1.00 82.55  ? 372  VAL A CA  1 
ATOM   2791 C C   . VAL A 1 372 ? 138.653 120.796 155.214 1.00 90.05  ? 372  VAL A C   1 
ATOM   2792 O O   . VAL A 1 372 ? 139.277 120.415 156.212 1.00 94.21  ? 372  VAL A O   1 
ATOM   2793 C CB  . VAL A 1 372 ? 137.811 119.091 153.548 1.00 86.12  ? 372  VAL A CB  1 
ATOM   2794 C CG1 . VAL A 1 372 ? 139.010 118.245 153.928 1.00 89.58  ? 372  VAL A CG1 1 
ATOM   2795 C CG2 . VAL A 1 372 ? 136.636 118.207 153.185 1.00 92.25  ? 372  VAL A CG2 1 
ATOM   2796 N N   . ASN A 1 373 ? 139.019 121.878 154.524 1.00 96.55  ? 373  ASN A N   1 
ATOM   2797 C CA  . ASN A 1 373 ? 140.175 122.666 154.933 1.00 93.34  ? 373  ASN A CA  1 
ATOM   2798 C C   . ASN A 1 373 ? 139.994 123.202 156.345 1.00 101.80 ? 373  ASN A C   1 
ATOM   2799 O O   . ASN A 1 373 ? 140.915 123.154 157.167 1.00 106.46 ? 373  ASN A O   1 
ATOM   2800 C CB  . ASN A 1 373 ? 140.389 123.820 153.954 1.00 92.55  ? 373  ASN A CB  1 
ATOM   2801 C CG  . ASN A 1 373 ? 140.759 123.345 152.569 1.00 105.93 ? 373  ASN A CG  1 
ATOM   2802 O OD1 . ASN A 1 373 ? 140.932 122.150 152.336 1.00 116.37 ? 373  ASN A OD1 1 
ATOM   2803 N ND2 . ASN A 1 373 ? 140.878 124.281 151.637 1.00 107.51 ? 373  ASN A ND2 1 
ATOM   2804 N N   . VAL A 1 374 ? 138.803 123.722 156.641 1.00 99.44  ? 374  VAL A N   1 
ATOM   2805 C CA  . VAL A 1 374 ? 138.551 124.285 157.963 1.00 93.12  ? 374  VAL A CA  1 
ATOM   2806 C C   . VAL A 1 374 ? 138.542 123.190 159.020 1.00 96.71  ? 374  VAL A C   1 
ATOM   2807 O O   . VAL A 1 374 ? 139.084 123.366 160.117 1.00 99.80  ? 374  VAL A O   1 
ATOM   2808 C CB  . VAL A 1 374 ? 137.236 125.083 157.956 1.00 91.69  ? 374  VAL A CB  1 
ATOM   2809 C CG1 . VAL A 1 374 ? 136.811 125.424 159.375 1.00 95.17  ? 374  VAL A CG1 1 
ATOM   2810 C CG2 . VAL A 1 374 ? 137.399 126.344 157.121 1.00 97.76  ? 374  VAL A CG2 1 
ATOM   2811 N N   . THR A 1 375 ? 137.933 122.042 158.716 1.00 90.16  ? 375  THR A N   1 
ATOM   2812 C CA  . THR A 1 375 ? 137.905 120.955 159.689 1.00 85.72  ? 375  THR A CA  1 
ATOM   2813 C C   . THR A 1 375 ? 139.311 120.458 160.002 1.00 88.22  ? 375  THR A C   1 
ATOM   2814 O O   . THR A 1 375 ? 139.610 120.087 161.147 1.00 96.56  ? 375  THR A O   1 
ATOM   2815 C CB  . THR A 1 375 ? 137.040 119.808 159.170 1.00 91.26  ? 375  THR A CB  1 
ATOM   2816 O OG1 . THR A 1 375 ? 135.724 120.293 158.879 1.00 100.52 ? 375  THR A OG1 1 
ATOM   2817 C CG2 . THR A 1 375 ? 136.951 118.696 160.201 1.00 91.56  ? 375  THR A CG2 1 
ATOM   2818 N N   . GLY A 1 376 ? 140.181 120.424 158.990 1.00 80.48  ? 376  GLY A N   1 
ATOM   2819 C CA  . GLY A 1 376 ? 141.531 119.934 159.202 1.00 79.10  ? 376  GLY A CA  1 
ATOM   2820 C C   . GLY A 1 376 ? 142.299 120.734 160.233 1.00 83.25  ? 376  GLY A C   1 
ATOM   2821 O O   . GLY A 1 376 ? 143.050 120.168 161.028 1.00 89.17  ? 376  GLY A O   1 
ATOM   2822 N N   . ASP A 1 377 ? 142.124 122.056 160.238 1.00 105.75 ? 377  ASP A N   1 
ATOM   2823 C CA  . ASP A 1 377 ? 142.833 122.888 161.204 1.00 106.34 ? 377  ASP A CA  1 
ATOM   2824 C C   . ASP A 1 377 ? 142.456 122.517 162.632 1.00 111.34 ? 377  ASP A C   1 
ATOM   2825 O O   . ASP A 1 377 ? 143.332 122.340 163.488 1.00 110.86 ? 377  ASP A O   1 
ATOM   2826 C CB  . ASP A 1 377 ? 142.522 124.360 160.944 1.00 109.18 ? 377  ASP A CB  1 
ATOM   2827 C CG  . ASP A 1 377 ? 143.149 124.873 159.667 1.00 111.56 ? 377  ASP A CG  1 
ATOM   2828 O OD1 . ASP A 1 377 ? 143.622 126.029 159.665 1.00 116.28 ? 377  ASP A OD1 1 
ATOM   2829 O OD2 . ASP A 1 377 ? 143.171 124.127 158.667 1.00 108.95 ? 377  ASP A OD2 1 
ATOM   2830 N N   . LEU A 1 378 ? 141.158 122.393 162.908 1.00 104.41 ? 378  LEU A N   1 
ATOM   2831 C CA  . LEU A 1 378 ? 140.720 122.068 164.260 1.00 96.22  ? 378  LEU A CA  1 
ATOM   2832 C C   . LEU A 1 378 ? 141.141 120.657 164.650 1.00 99.80  ? 378  LEU A C   1 
ATOM   2833 O O   . LEU A 1 378 ? 141.531 120.414 165.800 1.00 105.20 ? 378  LEU A O   1 
ATOM   2834 C CB  . LEU A 1 378 ? 139.208 122.237 164.367 1.00 93.19  ? 378  LEU A CB  1 
ATOM   2835 C CG  . LEU A 1 378 ? 138.747 123.693 164.305 1.00 95.66  ? 378  LEU A CG  1 
ATOM   2836 C CD1 . LEU A 1 378 ? 137.330 123.803 163.771 1.00 99.59  ? 378  LEU A CD1 1 
ATOM   2837 C CD2 . LEU A 1 378 ? 138.852 124.334 165.676 1.00 103.07 ? 378  LEU A CD2 1 
ATOM   2838 N N   . VAL A 1 379 ? 141.073 119.713 163.710 1.00 93.84  ? 379  VAL A N   1 
ATOM   2839 C CA  . VAL A 1 379 ? 141.518 118.356 164.014 1.00 91.14  ? 379  VAL A CA  1 
ATOM   2840 C C   . VAL A 1 379 ? 143.002 118.350 164.358 1.00 93.46  ? 379  VAL A C   1 
ATOM   2841 O O   . VAL A 1 379 ? 143.437 117.673 165.299 1.00 95.72  ? 379  VAL A O   1 
ATOM   2842 C CB  . VAL A 1 379 ? 141.202 117.414 162.839 1.00 90.12  ? 379  VAL A CB  1 
ATOM   2843 C CG1 . VAL A 1 379 ? 141.856 116.066 163.056 1.00 89.83  ? 379  VAL A CG1 1 
ATOM   2844 C CG2 . VAL A 1 379 ? 139.703 117.259 162.678 1.00 92.81  ? 379  VAL A CG2 1 
ATOM   2845 N N   . ALA A 1 380 ? 143.804 119.100 163.599 1.00 91.18  ? 380  ALA A N   1 
ATOM   2846 C CA  . ALA A 1 380 ? 145.228 119.196 163.894 1.00 87.08  ? 380  ALA A CA  1 
ATOM   2847 C C   . ALA A 1 380 ? 145.461 119.809 165.264 1.00 92.42  ? 380  ALA A C   1 
ATOM   2848 O O   . ALA A 1 380 ? 146.329 119.353 166.017 1.00 100.77 ? 380  ALA A O   1 
ATOM   2849 C CB  . ALA A 1 380 ? 145.930 120.027 162.824 1.00 87.34  ? 380  ALA A CB  1 
ATOM   2850 N N   . THR A 1 381 ? 144.713 120.860 165.597 1.00 87.22  ? 381  THR A N   1 
ATOM   2851 C CA  . THR A 1 381 ? 144.849 121.459 166.919 1.00 91.15  ? 381  THR A CA  1 
ATOM   2852 C C   . THR A 1 381 ? 144.577 120.433 168.007 1.00 91.78  ? 381  THR A C   1 
ATOM   2853 O O   . THR A 1 381 ? 145.348 120.311 168.967 1.00 93.06  ? 381  THR A O   1 
ATOM   2854 C CB  . THR A 1 381 ? 143.894 122.642 167.064 1.00 89.57  ? 381  THR A CB  1 
ATOM   2855 O OG1 . THR A 1 381 ? 144.006 123.494 165.919 1.00 95.61  ? 381  THR A OG1 1 
ATOM   2856 C CG2 . THR A 1 381 ? 144.207 123.430 168.322 1.00 91.78  ? 381  THR A CG2 1 
ATOM   2857 N N   . ALA A 1 382 ? 143.484 119.682 167.870 1.00 93.76  ? 382  ALA A N   1 
ATOM   2858 C CA  . ALA A 1 382 ? 143.153 118.685 168.880 1.00 91.59  ? 382  ALA A CA  1 
ATOM   2859 C C   . ALA A 1 382 ? 144.250 117.637 168.996 1.00 92.71  ? 382  ALA A C   1 
ATOM   2860 O O   . ALA A 1 382 ? 144.652 117.272 170.106 1.00 101.02 ? 382  ALA A O   1 
ATOM   2861 C CB  . ALA A 1 382 ? 141.816 118.027 168.547 1.00 92.62  ? 382  ALA A CB  1 
ATOM   2862 N N   . ILE A 1 383 ? 144.753 117.148 167.861 1.00 87.98  ? 383  ILE A N   1 
ATOM   2863 C CA  . ILE A 1 383 ? 145.767 116.097 167.896 1.00 89.48  ? 383  ILE A CA  1 
ATOM   2864 C C   . ILE A 1 383 ? 147.048 116.606 168.544 1.00 95.38  ? 383  ILE A C   1 
ATOM   2865 O O   . ILE A 1 383 ? 147.659 115.921 169.371 1.00 102.70 ? 383  ILE A O   1 
ATOM   2866 C CB  . ILE A 1 383 ? 146.028 115.551 166.483 1.00 86.35  ? 383  ILE A CB  1 
ATOM   2867 C CG1 . ILE A 1 383 ? 144.804 114.784 165.988 1.00 90.45  ? 383  ILE A CG1 1 
ATOM   2868 C CG2 . ILE A 1 383 ? 147.255 114.663 166.478 1.00 88.81  ? 383  ILE A CG2 1 
ATOM   2869 C CD1 . ILE A 1 383 ? 144.579 114.883 164.507 1.00 94.88  ? 383  ILE A CD1 1 
ATOM   2870 N N   . VAL A 1 384 ? 147.482 117.810 168.171 1.00 93.19  ? 384  VAL A N   1 
ATOM   2871 C CA  . VAL A 1 384 ? 148.713 118.354 168.736 1.00 91.33  ? 384  VAL A CA  1 
ATOM   2872 C C   . VAL A 1 384 ? 148.558 118.568 170.235 1.00 93.33  ? 384  VAL A C   1 
ATOM   2873 O O   . VAL A 1 384 ? 149.463 118.260 171.018 1.00 89.82  ? 384  VAL A O   1 
ATOM   2874 C CB  . VAL A 1 384 ? 149.111 119.654 168.017 1.00 82.40  ? 384  VAL A CB  1 
ATOM   2875 C CG1 . VAL A 1 384 ? 150.268 120.321 168.739 1.00 88.45  ? 384  VAL A CG1 1 
ATOM   2876 C CG2 . VAL A 1 384 ? 149.490 119.366 166.576 1.00 88.20  ? 384  VAL A CG2 1 
ATOM   2877 N N   . ALA A 1 385 ? 147.409 119.098 170.660 1.00 106.35 ? 385  ALA A N   1 
ATOM   2878 C CA  . ALA A 1 385 ? 147.180 119.276 172.089 1.00 107.76 ? 385  ALA A CA  1 
ATOM   2879 C C   . ALA A 1 385 ? 147.223 117.940 172.816 1.00 110.00 ? 385  ALA A C   1 
ATOM   2880 O O   . ALA A 1 385 ? 147.827 117.826 173.889 1.00 109.29 ? 385  ALA A O   1 
ATOM   2881 C CB  . ALA A 1 385 ? 145.840 119.971 172.323 1.00 112.24 ? 385  ALA A CB  1 
ATOM   2882 N N   . ARG A 1 386 ? 146.595 116.913 172.242 1.00 123.42 ? 386  ARG A N   1 
ATOM   2883 C CA  . ARG A 1 386 ? 146.615 115.591 172.854 1.00 122.70 ? 386  ARG A CA  1 
ATOM   2884 C C   . ARG A 1 386 ? 148.027 115.031 172.951 1.00 123.25 ? 386  ARG A C   1 
ATOM   2885 O O   . ARG A 1 386 ? 148.383 114.455 173.984 1.00 123.11 ? 386  ARG A O   1 
ATOM   2886 C CB  . ARG A 1 386 ? 145.728 114.639 172.050 1.00 125.65 ? 386  ARG A CB  1 
ATOM   2887 C CG  . ARG A 1 386 ? 145.725 113.190 172.523 1.00 128.58 ? 386  ARG A CG  1 
ATOM   2888 C CD  . ARG A 1 386 ? 145.629 113.059 174.039 1.00 131.23 ? 386  ARG A CD  1 
ATOM   2889 N NE  . ARG A 1 386 ? 145.504 111.668 174.459 1.00 134.59 ? 386  ARG A NE  1 
ATOM   2890 C CZ  . ARG A 1 386 ? 146.448 110.748 174.308 1.00 130.66 ? 386  ARG A CZ  1 
ATOM   2891 N NH1 . ARG A 1 386 ? 147.625 111.042 173.779 1.00 125.31 ? 386  ARG A NH1 1 
ATOM   2892 N NH2 . ARG A 1 386 ? 146.206 109.501 174.702 1.00 131.29 ? 386  ARG A NH2 1 
ATOM   2893 N N   . THR A 1 387 ? 148.843 115.200 171.912 1.00 114.62 ? 387  THR A N   1 
ATOM   2894 C CA  . THR A 1 387 ? 150.211 114.702 171.940 1.00 115.30 ? 387  THR A CA  1 
ATOM   2895 C C   . THR A 1 387 ? 151.020 115.311 173.073 1.00 113.31 ? 387  THR A C   1 
ATOM   2896 O O   . THR A 1 387 ? 151.754 114.590 173.758 1.00 112.37 ? 387  THR A O   1 
ATOM   2897 C CB  . THR A 1 387 ? 150.905 114.990 170.607 1.00 117.92 ? 387  THR A CB  1 
ATOM   2898 O OG1 . THR A 1 387 ? 150.250 114.265 169.559 1.00 119.86 ? 387  THR A OG1 1 
ATOM   2899 C CG2 . THR A 1 387 ? 152.368 114.578 170.664 1.00 114.63 ? 387  THR A CG2 1 
ATOM   2900 N N   . GLU A 1 388 ? 150.906 116.616 173.285 1.00 110.00 ? 388  GLU A N   1 
ATOM   2901 C CA  . GLU A 1 388 ? 151.462 117.246 174.472 1.00 114.09 ? 388  GLU A CA  1 
ATOM   2902 C C   . GLU A 1 388 ? 150.523 116.962 175.643 1.00 119.03 ? 388  GLU A C   1 
ATOM   2903 O O   . GLU A 1 388 ? 149.564 116.193 175.534 1.00 119.53 ? 388  GLU A O   1 
ATOM   2904 C CB  . GLU A 1 388 ? 151.658 118.741 174.239 1.00 114.62 ? 388  GLU A CB  1 
ATOM   2905 C CG  . GLU A 1 388 ? 152.775 119.079 173.259 1.00 118.67 ? 388  GLU A CG  1 
ATOM   2906 C CD  . GLU A 1 388 ? 154.027 119.618 173.935 1.00 122.03 ? 388  GLU A CD  1 
ATOM   2907 O OE1 . GLU A 1 388 ? 155.062 119.744 173.248 1.00 118.95 ? 388  GLU A OE1 1 
ATOM   2908 O OE2 . GLU A 1 388 ? 153.982 119.920 175.146 1.00 124.29 ? 388  GLU A OE2 1 
ATOM   2909 N N   . ASN A 1 389 ? 150.788 117.586 176.785 1.00 130.80 ? 389  ASN A N   1 
ATOM   2910 C CA  . ASN A 1 389 ? 149.899 117.462 177.931 1.00 132.25 ? 389  ASN A CA  1 
ATOM   2911 C C   . ASN A 1 389 ? 148.727 118.418 177.750 1.00 134.71 ? 389  ASN A C   1 
ATOM   2912 O O   . ASN A 1 389 ? 148.856 119.622 177.992 1.00 133.79 ? 389  ASN A O   1 
ATOM   2913 C CB  . ASN A 1 389 ? 150.649 117.755 179.228 1.00 131.60 ? 389  ASN A CB  1 
ATOM   2914 C CG  . ASN A 1 389 ? 151.040 116.492 179.975 1.00 131.00 ? 389  ASN A CG  1 
ATOM   2915 O OD1 . ASN A 1 389 ? 150.775 115.378 179.523 1.00 126.49 ? 389  ASN A OD1 1 
ATOM   2916 N ND2 . ASN A 1 389 ? 151.676 116.662 181.128 1.00 130.77 ? 389  ASN A ND2 1 
ATOM   2917 N N   . GLU A 1 390 ? 147.590 117.881 177.320 1.00 135.61 ? 390  GLU A N   1 
ATOM   2918 C CA  . GLU A 1 390 ? 146.411 118.690 177.038 1.00 132.78 ? 390  GLU A CA  1 
ATOM   2919 C C   . GLU A 1 390 ? 145.978 119.474 178.270 1.00 138.04 ? 390  GLU A C   1 
ATOM   2920 O O   . GLU A 1 390 ? 145.291 120.489 178.164 1.00 139.56 ? 390  GLU A O   1 
ATOM   2921 C CB  . GLU A 1 390 ? 145.265 117.802 176.548 1.00 128.51 ? 390  GLU A CB  1 
ATOM   2922 C CG  . GLU A 1 390 ? 144.050 118.566 176.051 1.00 129.34 ? 390  GLU A CG  1 
ATOM   2923 C CD  . GLU A 1 390 ? 142.922 117.646 175.630 1.00 132.95 ? 390  GLU A CD  1 
ATOM   2924 O OE1 . GLU A 1 390 ? 142.469 116.838 176.467 1.00 129.79 ? 390  GLU A OE1 1 
ATOM   2925 O OE2 . GLU A 1 390 ? 142.491 117.728 174.461 1.00 132.93 ? 390  GLU A OE2 1 
HETATM 2926 N N   . ASP B 2 .   ? 138.271 128.317 148.880 1.00 105.55 ? 1000 ASP A N   1 
HETATM 2927 C CA  . ASP B 2 .   ? 139.265 127.437 149.554 1.00 102.09 ? 1000 ASP A CA  1 
HETATM 2928 C C   . ASP B 2 .   ? 139.640 127.995 150.919 1.00 108.39 ? 1000 ASP A C   1 
HETATM 2929 O O   . ASP B 2 .   ? 139.950 127.246 151.845 1.00 111.71 ? 1000 ASP A O   1 
HETATM 2930 C CB  . ASP B 2 .   ? 140.516 127.285 148.691 1.00 107.11 ? 1000 ASP A CB  1 
HETATM 2931 C CG  . ASP B 2 .   ? 140.264 126.466 147.444 1.00 116.91 ? 1000 ASP A CG  1 
HETATM 2932 O OD1 . ASP B 2 .   ? 139.671 127.005 146.487 1.00 116.18 ? 1000 ASP A OD1 1 
HETATM 2933 O OD2 . ASP B 2 .   ? 140.657 125.282 147.420 1.00 122.16 ? 1000 ASP A OD2 1 
HETATM 2934 O OXT . ASP B 2 .   ? 139.640 129.207 151.130 1.00 109.75 ? 1000 ASP A OXT 1 
# 
