data_9BGZ
# 
_entry.id   9BGZ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BGZ         pdb_00009bgz 10.2210/pdb9bgz/pdb 
WWPDB D_1000283050 ?            ?                   
EMDB  EMD-44527    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-12 ? 
2 'EM metadata'     1 0 2025-03-12 ? 
3 'Half map'        1 0 2025-03-12 1 
4 'Half map'        1 0 2025-03-12 2 
5 Image             1 0 2025-03-12 ? 
6 'Primary map'     1 0 2025-03-12 ? 
7 'Structure model' 1 1 2025-05-14 ? 
8 'EM metadata'     1 1 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 7 'Structure model' 'Data collection'      
2 8 'EM metadata'     'Data processing'      
3 8 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 7 'Structure model' em_admin    
2 7 'Structure model' em_software 
3 8 'EM metadata'     em_admin    
4 8 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 7 'Structure model' '_em_admin.last_update' 
2 7 'Structure model' '_em_software.name'     
3 8 'EM metadata'     '_em_admin.last_update' 
4 8 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BGZ 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Ancestral uncoupled aspartate transporter, apo conditions, high-affinity state' 
_pdbx_database_related.db_id          EMD-44527 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              olb2003@med.cornell.edu 
_pdbx_contact_author.name_first         Olga 
_pdbx_contact_author.name_last          Boudker 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-6965-0851 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Reddy, K.D.' 1 ? 
'Boudker, O.' 2 ? 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Biorxiv 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2692-8205 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'Evolutionary analysis reveals the origin of sodium coupling in glutamate transporters.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1101/2023.12.03.569786 
_citation.pdbx_database_id_PubMed   38106174 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Reddy, K.D.'  1 0000-0002-0475-8375 
primary 'Rasool, B.'   2 ?                   
primary 'Akher, F.B.'  3 ?                   
primary 'Kutlesic, N.' 4 ?                   
primary 'Pant, S.'     5 ?                   
primary 'Boudker, O.'  6 ?                   
# 
_entity.id                         1 
_entity.type                       polymer 
_entity.src_method                 man 
_entity.pdbx_description           'Aspartate transporter' 
_entity.formula_weight             43910.488 
_entity.pdbx_number_of_molecules   1 
_entity.pdbx_ec                    ? 
_entity.pdbx_mutation              ? 
_entity.pdbx_fragment              ? 
_entity.details                    'apo conditions, high-affinity state' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MSLYHKILIGFVLGVIVGLIFGDKAEFIKPLGDIFLRLLKMIVVPLVFSTIVTGIASMGDVKKLGRIGAKTLIYYMITTT
LAVTIGLILANIFKPGKGLSLGEIHEVAHPNAPSFTETLLNMIPTNPFEAMAEGNMLQIIVFAIFFGIALALMGEKAEPV
KKFFDSASEVMFKITDIVMKFAPYGVFALMAWTVGKYGLDVLAPLGKLILTVYLGCIIHILIVYTLLLRFLCKINPLRFF
KKIKEAMLVAFSTCSSAATLPVTMRVAEELGVPESIASFTLPLGATINMDGTALYQGVAAIFVAQAYGVELTLGQQLTIV
LTAVLASIGTAGVPGAGLVMLTMVLTSVGLPLEGIALIAGIDRILDMARTTVNVTGDLVATAIVARTENELNREMTATPL
EVLESKTIAL
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MSLYHKILIGFVLGVIVGLIFGDKAEFIKPLGDIFLRLLKMIVVPLVFSTIVTGIASMGDVKKLGRIGAKTLIYYMITTT
LAVTIGLILANIFKPGKGLSLGEIHEVAHPNAPSFTETLLNMIPTNPFEAMAEGNMLQIIVFAIFFGIALALMGEKAEPV
KKFFDSASEVMFKITDIVMKFAPYGVFALMAWTVGKYGLDVLAPLGKLILTVYLGCIIHILIVYTLLLRFLCKINPLRFF
KKIKEAMLVAFSTCSSAATLPVTMRVAEELGVPESIASFTLPLGATINMDGTALYQGVAAIFVAQAYGVELTLGQQLTIV
LTAVLASIGTAGVPGAGLVMLTMVLTSVGLPLEGIALIAGIDRILDMARTTVNVTGDLVATAIVARTENELNREMTATPL
EVLESKTIAL
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   SER n 
1 3   LEU n 
1 4   TYR n 
1 5   HIS n 
1 6   LYS n 
1 7   ILE n 
1 8   LEU n 
1 9   ILE n 
1 10  GLY n 
1 11  PHE n 
1 12  VAL n 
1 13  LEU n 
1 14  GLY n 
1 15  VAL n 
1 16  ILE n 
1 17  VAL n 
1 18  GLY n 
1 19  LEU n 
1 20  ILE n 
1 21  PHE n 
1 22  GLY n 
1 23  ASP n 
1 24  LYS n 
1 25  ALA n 
1 26  GLU n 
1 27  PHE n 
1 28  ILE n 
1 29  LYS n 
1 30  PRO n 
1 31  LEU n 
1 32  GLY n 
1 33  ASP n 
1 34  ILE n 
1 35  PHE n 
1 36  LEU n 
1 37  ARG n 
1 38  LEU n 
1 39  LEU n 
1 40  LYS n 
1 41  MET n 
1 42  ILE n 
1 43  VAL n 
1 44  VAL n 
1 45  PRO n 
1 46  LEU n 
1 47  VAL n 
1 48  PHE n 
1 49  SER n 
1 50  THR n 
1 51  ILE n 
1 52  VAL n 
1 53  THR n 
1 54  GLY n 
1 55  ILE n 
1 56  ALA n 
1 57  SER n 
1 58  MET n 
1 59  GLY n 
1 60  ASP n 
1 61  VAL n 
1 62  LYS n 
1 63  LYS n 
1 64  LEU n 
1 65  GLY n 
1 66  ARG n 
1 67  ILE n 
1 68  GLY n 
1 69  ALA n 
1 70  LYS n 
1 71  THR n 
1 72  LEU n 
1 73  ILE n 
1 74  TYR n 
1 75  TYR n 
1 76  MET n 
1 77  ILE n 
1 78  THR n 
1 79  THR n 
1 80  THR n 
1 81  LEU n 
1 82  ALA n 
1 83  VAL n 
1 84  THR n 
1 85  ILE n 
1 86  GLY n 
1 87  LEU n 
1 88  ILE n 
1 89  LEU n 
1 90  ALA n 
1 91  ASN n 
1 92  ILE n 
1 93  PHE n 
1 94  LYS n 
1 95  PRO n 
1 96  GLY n 
1 97  LYS n 
1 98  GLY n 
1 99  LEU n 
1 100 SER n 
1 101 LEU n 
1 102 GLY n 
1 103 GLU n 
1 104 ILE n 
1 105 HIS n 
1 106 GLU n 
1 107 VAL n 
1 108 ALA n 
1 109 HIS n 
1 110 PRO n 
1 111 ASN n 
1 112 ALA n 
1 113 PRO n 
1 114 SER n 
1 115 PHE n 
1 116 THR n 
1 117 GLU n 
1 118 THR n 
1 119 LEU n 
1 120 LEU n 
1 121 ASN n 
1 122 MET n 
1 123 ILE n 
1 124 PRO n 
1 125 THR n 
1 126 ASN n 
1 127 PRO n 
1 128 PHE n 
1 129 GLU n 
1 130 ALA n 
1 131 MET n 
1 132 ALA n 
1 133 GLU n 
1 134 GLY n 
1 135 ASN n 
1 136 MET n 
1 137 LEU n 
1 138 GLN n 
1 139 ILE n 
1 140 ILE n 
1 141 VAL n 
1 142 PHE n 
1 143 ALA n 
1 144 ILE n 
1 145 PHE n 
1 146 PHE n 
1 147 GLY n 
1 148 ILE n 
1 149 ALA n 
1 150 LEU n 
1 151 ALA n 
1 152 LEU n 
1 153 MET n 
1 154 GLY n 
1 155 GLU n 
1 156 LYS n 
1 157 ALA n 
1 158 GLU n 
1 159 PRO n 
1 160 VAL n 
1 161 LYS n 
1 162 LYS n 
1 163 PHE n 
1 164 PHE n 
1 165 ASP n 
1 166 SER n 
1 167 ALA n 
1 168 SER n 
1 169 GLU n 
1 170 VAL n 
1 171 MET n 
1 172 PHE n 
1 173 LYS n 
1 174 ILE n 
1 175 THR n 
1 176 ASP n 
1 177 ILE n 
1 178 VAL n 
1 179 MET n 
1 180 LYS n 
1 181 PHE n 
1 182 ALA n 
1 183 PRO n 
1 184 TYR n 
1 185 GLY n 
1 186 VAL n 
1 187 PHE n 
1 188 ALA n 
1 189 LEU n 
1 190 MET n 
1 191 ALA n 
1 192 TRP n 
1 193 THR n 
1 194 VAL n 
1 195 GLY n 
1 196 LYS n 
1 197 TYR n 
1 198 GLY n 
1 199 LEU n 
1 200 ASP n 
1 201 VAL n 
1 202 LEU n 
1 203 ALA n 
1 204 PRO n 
1 205 LEU n 
1 206 GLY n 
1 207 LYS n 
1 208 LEU n 
1 209 ILE n 
1 210 LEU n 
1 211 THR n 
1 212 VAL n 
1 213 TYR n 
1 214 LEU n 
1 215 GLY n 
1 216 CYS n 
1 217 ILE n 
1 218 ILE n 
1 219 HIS n 
1 220 ILE n 
1 221 LEU n 
1 222 ILE n 
1 223 VAL n 
1 224 TYR n 
1 225 THR n 
1 226 LEU n 
1 227 LEU n 
1 228 LEU n 
1 229 ARG n 
1 230 PHE n 
1 231 LEU n 
1 232 CYS n 
1 233 LYS n 
1 234 ILE n 
1 235 ASN n 
1 236 PRO n 
1 237 LEU n 
1 238 ARG n 
1 239 PHE n 
1 240 PHE n 
1 241 LYS n 
1 242 LYS n 
1 243 ILE n 
1 244 LYS n 
1 245 GLU n 
1 246 ALA n 
1 247 MET n 
1 248 LEU n 
1 249 VAL n 
1 250 ALA n 
1 251 PHE n 
1 252 SER n 
1 253 THR n 
1 254 CYS n 
1 255 SER n 
1 256 SER n 
1 257 ALA n 
1 258 ALA n 
1 259 THR n 
1 260 LEU n 
1 261 PRO n 
1 262 VAL n 
1 263 THR n 
1 264 MET n 
1 265 ARG n 
1 266 VAL n 
1 267 ALA n 
1 268 GLU n 
1 269 GLU n 
1 270 LEU n 
1 271 GLY n 
1 272 VAL n 
1 273 PRO n 
1 274 GLU n 
1 275 SER n 
1 276 ILE n 
1 277 ALA n 
1 278 SER n 
1 279 PHE n 
1 280 THR n 
1 281 LEU n 
1 282 PRO n 
1 283 LEU n 
1 284 GLY n 
1 285 ALA n 
1 286 THR n 
1 287 ILE n 
1 288 ASN n 
1 289 MET n 
1 290 ASP n 
1 291 GLY n 
1 292 THR n 
1 293 ALA n 
1 294 LEU n 
1 295 TYR n 
1 296 GLN n 
1 297 GLY n 
1 298 VAL n 
1 299 ALA n 
1 300 ALA n 
1 301 ILE n 
1 302 PHE n 
1 303 VAL n 
1 304 ALA n 
1 305 GLN n 
1 306 ALA n 
1 307 TYR n 
1 308 GLY n 
1 309 VAL n 
1 310 GLU n 
1 311 LEU n 
1 312 THR n 
1 313 LEU n 
1 314 GLY n 
1 315 GLN n 
1 316 GLN n 
1 317 LEU n 
1 318 THR n 
1 319 ILE n 
1 320 VAL n 
1 321 LEU n 
1 322 THR n 
1 323 ALA n 
1 324 VAL n 
1 325 LEU n 
1 326 ALA n 
1 327 SER n 
1 328 ILE n 
1 329 GLY n 
1 330 THR n 
1 331 ALA n 
1 332 GLY n 
1 333 VAL n 
1 334 PRO n 
1 335 GLY n 
1 336 ALA n 
1 337 GLY n 
1 338 LEU n 
1 339 VAL n 
1 340 MET n 
1 341 LEU n 
1 342 THR n 
1 343 MET n 
1 344 VAL n 
1 345 LEU n 
1 346 THR n 
1 347 SER n 
1 348 VAL n 
1 349 GLY n 
1 350 LEU n 
1 351 PRO n 
1 352 LEU n 
1 353 GLU n 
1 354 GLY n 
1 355 ILE n 
1 356 ALA n 
1 357 LEU n 
1 358 ILE n 
1 359 ALA n 
1 360 GLY n 
1 361 ILE n 
1 362 ASP n 
1 363 ARG n 
1 364 ILE n 
1 365 LEU n 
1 366 ASP n 
1 367 MET n 
1 368 ALA n 
1 369 ARG n 
1 370 THR n 
1 371 THR n 
1 372 VAL n 
1 373 ASN n 
1 374 VAL n 
1 375 THR n 
1 376 GLY n 
1 377 ASP n 
1 378 LEU n 
1 379 VAL n 
1 380 ALA n 
1 381 THR n 
1 382 ALA n 
1 383 ILE n 
1 384 VAL n 
1 385 ALA n 
1 386 ARG n 
1 387 THR n 
1 388 GLU n 
1 389 ASN n 
1 390 GLU n 
1 391 LEU n 
1 392 ASN n 
1 393 ARG n 
1 394 GLU n 
1 395 MET n 
1 396 THR n 
1 397 ALA n 
1 398 THR n 
1 399 PRO n 
1 400 LEU n 
1 401 GLU n 
1 402 VAL n 
1 403 LEU n 
1 404 GLU n 
1 405 SER n 
1 406 LYS n 
1 407 THR n 
1 408 ILE n 
1 409 ALA n 
1 410 LEU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   410 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 ? 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'synthetic construct' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     32630 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE         ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE        ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE      ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking' y CYSTEINE        ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE       ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE         ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE       ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking' y ISOLEUCINE      ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE         ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE          ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE      ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE   ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE         ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE          ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking' y THREONINE       ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN      ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE        ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE          ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   1   MET MET A . n 
A 1 2   SER 2   2   2   SER SER A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   TYR 4   4   4   TYR TYR A . n 
A 1 5   HIS 5   5   5   HIS HIS A . n 
A 1 6   LYS 6   6   6   LYS LYS A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  GLY 10  10  10  GLY GLY A . n 
A 1 11  PHE 11  11  11  PHE PHE A . n 
A 1 12  VAL 12  12  12  VAL VAL A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  GLY 14  14  14  GLY GLY A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  ILE 16  16  16  ILE ILE A . n 
A 1 17  VAL 17  17  17  VAL VAL A . n 
A 1 18  GLY 18  18  18  GLY GLY A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  ILE 20  20  20  ILE ILE A . n 
A 1 21  PHE 21  21  21  PHE PHE A . n 
A 1 22  GLY 22  22  22  GLY GLY A . n 
A 1 23  ASP 23  23  23  ASP ASP A . n 
A 1 24  LYS 24  24  24  LYS LYS A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  GLU 26  26  26  GLU GLU A . n 
A 1 27  PHE 27  27  27  PHE PHE A . n 
A 1 28  ILE 28  28  28  ILE ILE A . n 
A 1 29  LYS 29  29  29  LYS LYS A . n 
A 1 30  PRO 30  30  30  PRO PRO A . n 
A 1 31  LEU 31  31  31  LEU LEU A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ASP 33  33  33  ASP ASP A . n 
A 1 34  ILE 34  34  34  ILE ILE A . n 
A 1 35  PHE 35  35  35  PHE PHE A . n 
A 1 36  LEU 36  36  36  LEU LEU A . n 
A 1 37  ARG 37  37  37  ARG ARG A . n 
A 1 38  LEU 38  38  38  LEU LEU A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  LYS 40  40  40  LYS LYS A . n 
A 1 41  MET 41  41  41  MET MET A . n 
A 1 42  ILE 42  42  42  ILE ILE A . n 
A 1 43  VAL 43  43  43  VAL VAL A . n 
A 1 44  VAL 44  44  44  VAL VAL A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  LEU 46  46  46  LEU LEU A . n 
A 1 47  VAL 47  47  47  VAL VAL A . n 
A 1 48  PHE 48  48  48  PHE PHE A . n 
A 1 49  SER 49  49  49  SER SER A . n 
A 1 50  THR 50  50  50  THR THR A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  VAL 52  52  52  VAL VAL A . n 
A 1 53  THR 53  53  53  THR THR A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  ILE 55  55  55  ILE ILE A . n 
A 1 56  ALA 56  56  56  ALA ALA A . n 
A 1 57  SER 57  57  57  SER SER A . n 
A 1 58  MET 58  58  58  MET MET A . n 
A 1 59  GLY 59  59  59  GLY GLY A . n 
A 1 60  ASP 60  60  60  ASP ASP A . n 
A 1 61  VAL 61  61  61  VAL VAL A . n 
A 1 62  LYS 62  62  62  LYS LYS A . n 
A 1 63  LYS 63  63  63  LYS LYS A . n 
A 1 64  LEU 64  64  64  LEU LEU A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  ARG 66  66  66  ARG ARG A . n 
A 1 67  ILE 67  67  67  ILE ILE A . n 
A 1 68  GLY 68  68  68  GLY GLY A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  LYS 70  70  70  LYS LYS A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  LEU 72  72  72  LEU LEU A . n 
A 1 73  ILE 73  73  73  ILE ILE A . n 
A 1 74  TYR 74  74  74  TYR TYR A . n 
A 1 75  TYR 75  75  75  TYR TYR A . n 
A 1 76  MET 76  76  76  MET MET A . n 
A 1 77  ILE 77  77  77  ILE ILE A . n 
A 1 78  THR 78  78  78  THR THR A . n 
A 1 79  THR 79  79  79  THR THR A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  LEU 81  81  81  LEU LEU A . n 
A 1 82  ALA 82  82  82  ALA ALA A . n 
A 1 83  VAL 83  83  83  VAL VAL A . n 
A 1 84  THR 84  84  84  THR THR A . n 
A 1 85  ILE 85  85  85  ILE ILE A . n 
A 1 86  GLY 86  86  86  GLY GLY A . n 
A 1 87  LEU 87  87  87  LEU LEU A . n 
A 1 88  ILE 88  88  88  ILE ILE A . n 
A 1 89  LEU 89  89  89  LEU LEU A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ASN 91  91  91  ASN ASN A . n 
A 1 92  ILE 92  92  92  ILE ILE A . n 
A 1 93  PHE 93  93  93  PHE PHE A . n 
A 1 94  LYS 94  94  94  LYS LYS A . n 
A 1 95  PRO 95  95  95  PRO PRO A . n 
A 1 96  GLY 96  96  96  GLY GLY A . n 
A 1 97  LYS 97  97  97  LYS LYS A . n 
A 1 98  GLY 98  98  98  GLY GLY A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 SER 100 100 100 SER SER A . n 
A 1 101 LEU 101 101 ?   ?   ?   A . n 
A 1 102 GLY 102 102 ?   ?   ?   A . n 
A 1 103 GLU 103 103 ?   ?   ?   A . n 
A 1 104 ILE 104 104 ?   ?   ?   A . n 
A 1 105 HIS 105 105 ?   ?   ?   A . n 
A 1 106 GLU 106 106 ?   ?   ?   A . n 
A 1 107 VAL 107 107 ?   ?   ?   A . n 
A 1 108 ALA 108 108 ?   ?   ?   A . n 
A 1 109 HIS 109 109 ?   ?   ?   A . n 
A 1 110 PRO 110 110 ?   ?   ?   A . n 
A 1 111 ASN 111 111 ?   ?   ?   A . n 
A 1 112 ALA 112 112 ?   ?   ?   A . n 
A 1 113 PRO 113 113 113 PRO PRO A . n 
A 1 114 SER 114 114 114 SER SER A . n 
A 1 115 PHE 115 115 115 PHE PHE A . n 
A 1 116 THR 116 116 116 THR THR A . n 
A 1 117 GLU 117 117 117 GLU GLU A . n 
A 1 118 THR 118 118 118 THR THR A . n 
A 1 119 LEU 119 119 119 LEU LEU A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 ASN 121 121 121 ASN ASN A . n 
A 1 122 MET 122 122 122 MET MET A . n 
A 1 123 ILE 123 123 123 ILE ILE A . n 
A 1 124 PRO 124 124 124 PRO PRO A . n 
A 1 125 THR 125 125 125 THR THR A . n 
A 1 126 ASN 126 126 126 ASN ASN A . n 
A 1 127 PRO 127 127 127 PRO PRO A . n 
A 1 128 PHE 128 128 128 PHE PHE A . n 
A 1 129 GLU 129 129 129 GLU GLU A . n 
A 1 130 ALA 130 130 130 ALA ALA A . n 
A 1 131 MET 131 131 131 MET MET A . n 
A 1 132 ALA 132 132 132 ALA ALA A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 GLY 134 134 134 GLY GLY A . n 
A 1 135 ASN 135 135 135 ASN ASN A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 GLN 138 138 138 GLN GLN A . n 
A 1 139 ILE 139 139 139 ILE ILE A . n 
A 1 140 ILE 140 140 140 ILE ILE A . n 
A 1 141 VAL 141 141 141 VAL VAL A . n 
A 1 142 PHE 142 142 142 PHE PHE A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ILE 144 144 144 ILE ILE A . n 
A 1 145 PHE 145 145 145 PHE PHE A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 GLY 147 147 147 GLY GLY A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 LEU 152 152 152 LEU LEU A . n 
A 1 153 MET 153 153 153 MET MET A . n 
A 1 154 GLY 154 154 154 GLY GLY A . n 
A 1 155 GLU 155 155 155 GLU GLU A . n 
A 1 156 LYS 156 156 156 LYS LYS A . n 
A 1 157 ALA 157 157 157 ALA ALA A . n 
A 1 158 GLU 158 158 158 GLU GLU A . n 
A 1 159 PRO 159 159 159 PRO PRO A . n 
A 1 160 VAL 160 160 160 VAL VAL A . n 
A 1 161 LYS 161 161 161 LYS LYS A . n 
A 1 162 LYS 162 162 162 LYS LYS A . n 
A 1 163 PHE 163 163 163 PHE PHE A . n 
A 1 164 PHE 164 164 164 PHE PHE A . n 
A 1 165 ASP 165 165 165 ASP ASP A . n 
A 1 166 SER 166 166 166 SER SER A . n 
A 1 167 ALA 167 167 167 ALA ALA A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 VAL 170 170 170 VAL VAL A . n 
A 1 171 MET 171 171 171 MET MET A . n 
A 1 172 PHE 172 172 172 PHE PHE A . n 
A 1 173 LYS 173 173 173 LYS LYS A . n 
A 1 174 ILE 174 174 174 ILE ILE A . n 
A 1 175 THR 175 175 175 THR THR A . n 
A 1 176 ASP 176 176 176 ASP ASP A . n 
A 1 177 ILE 177 177 177 ILE ILE A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 MET 179 179 179 MET MET A . n 
A 1 180 LYS 180 180 180 LYS LYS A . n 
A 1 181 PHE 181 181 181 PHE PHE A . n 
A 1 182 ALA 182 182 182 ALA ALA A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 TYR 184 184 184 TYR TYR A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 VAL 186 186 186 VAL VAL A . n 
A 1 187 PHE 187 187 187 PHE PHE A . n 
A 1 188 ALA 188 188 188 ALA ALA A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 MET 190 190 190 MET MET A . n 
A 1 191 ALA 191 191 191 ALA ALA A . n 
A 1 192 TRP 192 192 192 TRP TRP A . n 
A 1 193 THR 193 193 193 THR THR A . n 
A 1 194 VAL 194 194 194 VAL VAL A . n 
A 1 195 GLY 195 195 195 GLY GLY A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 TYR 197 197 197 TYR TYR A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 ASP 200 200 200 ASP ASP A . n 
A 1 201 VAL 201 201 201 VAL VAL A . n 
A 1 202 LEU 202 202 202 LEU LEU A . n 
A 1 203 ALA 203 203 203 ALA ALA A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 LEU 205 205 205 LEU LEU A . n 
A 1 206 GLY 206 206 206 GLY GLY A . n 
A 1 207 LYS 207 207 207 LYS LYS A . n 
A 1 208 LEU 208 208 208 LEU LEU A . n 
A 1 209 ILE 209 209 209 ILE ILE A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 THR 211 211 211 THR THR A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 TYR 213 213 213 TYR TYR A . n 
A 1 214 LEU 214 214 214 LEU LEU A . n 
A 1 215 GLY 215 215 215 GLY GLY A . n 
A 1 216 CYS 216 216 216 CYS CYS A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 ILE 218 218 218 ILE ILE A . n 
A 1 219 HIS 219 219 219 HIS HIS A . n 
A 1 220 ILE 220 220 220 ILE ILE A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 TYR 224 224 224 TYR TYR A . n 
A 1 225 THR 225 225 225 THR THR A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 LEU 227 227 227 LEU LEU A . n 
A 1 228 LEU 228 228 228 LEU LEU A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 PHE 230 230 230 PHE PHE A . n 
A 1 231 LEU 231 231 231 LEU LEU A . n 
A 1 232 CYS 232 232 232 CYS CYS A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 ILE 234 234 234 ILE ILE A . n 
A 1 235 ASN 235 235 235 ASN ASN A . n 
A 1 236 PRO 236 236 236 PRO PRO A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 ARG 238 238 238 ARG ARG A . n 
A 1 239 PHE 239 239 239 PHE PHE A . n 
A 1 240 PHE 240 240 240 PHE PHE A . n 
A 1 241 LYS 241 241 241 LYS LYS A . n 
A 1 242 LYS 242 242 242 LYS LYS A . n 
A 1 243 ILE 243 243 243 ILE ILE A . n 
A 1 244 LYS 244 244 244 LYS LYS A . n 
A 1 245 GLU 245 245 245 GLU GLU A . n 
A 1 246 ALA 246 246 246 ALA ALA A . n 
A 1 247 MET 247 247 247 MET MET A . n 
A 1 248 LEU 248 248 248 LEU LEU A . n 
A 1 249 VAL 249 249 249 VAL VAL A . n 
A 1 250 ALA 250 250 250 ALA ALA A . n 
A 1 251 PHE 251 251 251 PHE PHE A . n 
A 1 252 SER 252 252 252 SER SER A . n 
A 1 253 THR 253 253 253 THR THR A . n 
A 1 254 CYS 254 254 254 CYS CYS A . n 
A 1 255 SER 255 255 255 SER SER A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ALA 258 258 258 ALA ALA A . n 
A 1 259 THR 259 259 259 THR THR A . n 
A 1 260 LEU 260 260 260 LEU LEU A . n 
A 1 261 PRO 261 261 261 PRO PRO A . n 
A 1 262 VAL 262 262 262 VAL VAL A . n 
A 1 263 THR 263 263 263 THR THR A . n 
A 1 264 MET 264 264 264 MET MET A . n 
A 1 265 ARG 265 265 265 ARG ARG A . n 
A 1 266 VAL 266 266 266 VAL VAL A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 GLU 268 268 268 GLU GLU A . n 
A 1 269 GLU 269 269 269 GLU GLU A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 GLY 271 271 271 GLY GLY A . n 
A 1 272 VAL 272 272 272 VAL VAL A . n 
A 1 273 PRO 273 273 273 PRO PRO A . n 
A 1 274 GLU 274 274 274 GLU GLU A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 ILE 276 276 276 ILE ILE A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 SER 278 278 278 SER SER A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 THR 280 280 280 THR THR A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 LEU 283 283 283 LEU LEU A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 THR 286 286 286 THR THR A . n 
A 1 287 ILE 287 287 287 ILE ILE A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 MET 289 289 289 MET MET A . n 
A 1 290 ASP 290 290 290 ASP ASP A . n 
A 1 291 GLY 291 291 291 GLY GLY A . n 
A 1 292 THR 292 292 292 THR THR A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 TYR 295 295 295 TYR TYR A . n 
A 1 296 GLN 296 296 296 GLN GLN A . n 
A 1 297 GLY 297 297 297 GLY GLY A . n 
A 1 298 VAL 298 298 298 VAL VAL A . n 
A 1 299 ALA 299 299 299 ALA ALA A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 VAL 303 303 303 VAL VAL A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 GLN 305 305 305 GLN GLN A . n 
A 1 306 ALA 306 306 306 ALA ALA A . n 
A 1 307 TYR 307 307 307 TYR TYR A . n 
A 1 308 GLY 308 308 308 GLY GLY A . n 
A 1 309 VAL 309 309 309 VAL VAL A . n 
A 1 310 GLU 310 310 310 GLU GLU A . n 
A 1 311 LEU 311 311 311 LEU LEU A . n 
A 1 312 THR 312 312 312 THR THR A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 GLY 314 314 314 GLY GLY A . n 
A 1 315 GLN 315 315 315 GLN GLN A . n 
A 1 316 GLN 316 316 316 GLN GLN A . n 
A 1 317 LEU 317 317 317 LEU LEU A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 VAL 320 320 320 VAL VAL A . n 
A 1 321 LEU 321 321 321 LEU LEU A . n 
A 1 322 THR 322 322 322 THR THR A . n 
A 1 323 ALA 323 323 323 ALA ALA A . n 
A 1 324 VAL 324 324 324 VAL VAL A . n 
A 1 325 LEU 325 325 325 LEU LEU A . n 
A 1 326 ALA 326 326 326 ALA ALA A . n 
A 1 327 SER 327 327 327 SER SER A . n 
A 1 328 ILE 328 328 328 ILE ILE A . n 
A 1 329 GLY 329 329 ?   ?   ?   A . n 
A 1 330 THR 330 330 ?   ?   ?   A . n 
A 1 331 ALA 331 331 ?   ?   ?   A . n 
A 1 332 GLY 332 332 ?   ?   ?   A . n 
A 1 333 VAL 333 333 ?   ?   ?   A . n 
A 1 334 PRO 334 334 ?   ?   ?   A . n 
A 1 335 GLY 335 335 ?   ?   ?   A . n 
A 1 336 ALA 336 336 ?   ?   ?   A . n 
A 1 337 GLY 337 337 337 GLY GLY A . n 
A 1 338 LEU 338 338 338 LEU LEU A . n 
A 1 339 VAL 339 339 339 VAL VAL A . n 
A 1 340 MET 340 340 340 MET MET A . n 
A 1 341 LEU 341 341 341 LEU LEU A . n 
A 1 342 THR 342 342 342 THR THR A . n 
A 1 343 MET 343 343 343 MET MET A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 LEU 345 345 345 LEU LEU A . n 
A 1 346 THR 346 346 346 THR THR A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 VAL 348 348 348 VAL VAL A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 LEU 350 350 350 LEU LEU A . n 
A 1 351 PRO 351 351 351 PRO PRO A . n 
A 1 352 LEU 352 352 352 LEU LEU A . n 
A 1 353 GLU 353 353 353 GLU GLU A . n 
A 1 354 GLY 354 354 354 GLY GLY A . n 
A 1 355 ILE 355 355 355 ILE ILE A . n 
A 1 356 ALA 356 356 356 ALA ALA A . n 
A 1 357 LEU 357 357 357 LEU LEU A . n 
A 1 358 ILE 358 358 358 ILE ILE A . n 
A 1 359 ALA 359 359 359 ALA ALA A . n 
A 1 360 GLY 360 360 360 GLY GLY A . n 
A 1 361 ILE 361 361 361 ILE ILE A . n 
A 1 362 ASP 362 362 362 ASP ASP A . n 
A 1 363 ARG 363 363 363 ARG ARG A . n 
A 1 364 ILE 364 364 364 ILE ILE A . n 
A 1 365 LEU 365 365 365 LEU LEU A . n 
A 1 366 ASP 366 366 366 ASP ASP A . n 
A 1 367 MET 367 367 367 MET MET A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 ARG 369 369 369 ARG ARG A . n 
A 1 370 THR 370 370 370 THR THR A . n 
A 1 371 THR 371 371 371 THR THR A . n 
A 1 372 VAL 372 372 372 VAL VAL A . n 
A 1 373 ASN 373 373 373 ASN ASN A . n 
A 1 374 VAL 374 374 374 VAL VAL A . n 
A 1 375 THR 375 375 375 THR THR A . n 
A 1 376 GLY 376 376 376 GLY GLY A . n 
A 1 377 ASP 377 377 377 ASP ASP A . n 
A 1 378 LEU 378 378 378 LEU LEU A . n 
A 1 379 VAL 379 379 379 VAL VAL A . n 
A 1 380 ALA 380 380 380 ALA ALA A . n 
A 1 381 THR 381 381 381 THR THR A . n 
A 1 382 ALA 382 382 382 ALA ALA A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 VAL 384 384 384 VAL VAL A . n 
A 1 385 ALA 385 385 385 ALA ALA A . n 
A 1 386 ARG 386 386 386 ARG ARG A . n 
A 1 387 THR 387 387 387 THR THR A . n 
A 1 388 GLU 388 388 388 GLU GLU A . n 
A 1 389 ASN 389 389 389 ASN ASN A . n 
A 1 390 GLU 390 390 ?   ?   ?   A . n 
A 1 391 LEU 391 391 ?   ?   ?   A . n 
A 1 392 ASN 392 392 ?   ?   ?   A . n 
A 1 393 ARG 393 393 ?   ?   ?   A . n 
A 1 394 GLU 394 394 ?   ?   ?   A . n 
A 1 395 MET 395 395 ?   ?   ?   A . n 
A 1 396 THR 396 396 ?   ?   ?   A . n 
A 1 397 ALA 397 397 ?   ?   ?   A . n 
A 1 398 THR 398 398 ?   ?   ?   A . n 
A 1 399 PRO 399 399 ?   ?   ?   A . n 
A 1 400 LEU 400 400 ?   ?   ?   A . n 
A 1 401 GLU 401 401 ?   ?   ?   A . n 
A 1 402 VAL 402 402 ?   ?   ?   A . n 
A 1 403 LEU 403 403 ?   ?   ?   A . n 
A 1 404 GLU 404 404 ?   ?   ?   A . n 
A 1 405 SER 405 405 ?   ?   ?   A . n 
A 1 406 LYS 406 406 ?   ?   ?   A . n 
A 1 407 THR 407 407 ?   ?   ?   A . n 
A 1 408 ILE 408 408 ?   ?   ?   A . n 
A 1 409 ALA 409 409 ?   ?   ?   A . n 
A 1 410 LEU 410 410 ?   ?   ?   A . n 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BGZ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BGZ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BGZ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9BGZ 
_struct.title                        'Ancestral uncoupled aspartate transporter, apo conditions, high-affinity state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BGZ 
_struct_keywords.text            'Transporter, ion-uncoupled, ancestral, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
_struct_asym.id                            A 
_struct_asym.pdbx_blank_PDB_chainid_flag   N 
_struct_asym.pdbx_modified                 N 
_struct_asym.entity_id                     1 
_struct_asym.details                       ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    PDB 
_struct_ref.db_code                    9BGZ 
_struct_ref.pdbx_db_accession          9BGZ 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   ? 
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9BGZ 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 410 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             9BGZ 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  410 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       410 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 2   ? GLY A 22  ? SER A 2   GLY A 22  1 ? 21 
HELX_P HELX_P2  AA2 ASP A 23  ? PHE A 27  ? ASP A 23  PHE A 27  5 ? 5  
HELX_P HELX_P3  AA3 ILE A 28  ? MET A 41  ? ILE A 28  MET A 41  1 ? 14 
HELX_P HELX_P4  AA4 ILE A 42  ? GLY A 59  ? ILE A 42  GLY A 59  1 ? 18 
HELX_P HELX_P5  AA5 ASP A 60  ? PHE A 93  ? ASP A 60  PHE A 93  1 ? 34 
HELX_P HELX_P6  AA6 SER A 114 ? LEU A 120 ? SER A 114 LEU A 120 1 ? 7  
HELX_P HELX_P7  AA7 ASN A 126 ? GLY A 134 ? ASN A 126 GLY A 134 1 ? 9  
HELX_P HELX_P8  AA8 ASN A 135 ? GLY A 154 ? ASN A 135 GLY A 154 1 ? 20 
HELX_P HELX_P9  AA9 ALA A 157 ? LYS A 180 ? ALA A 157 LYS A 180 1 ? 24 
HELX_P HELX_P10 AB1 PHE A 181 ? TYR A 197 ? PHE A 181 TYR A 197 1 ? 17 
HELX_P HELX_P11 AB2 GLY A 198 ? VAL A 223 ? GLY A 198 VAL A 223 1 ? 26 
HELX_P HELX_P12 AB3 VAL A 223 ? LEU A 231 ? VAL A 223 LEU A 231 1 ? 9  
HELX_P HELX_P13 AB4 ASN A 235 ? CYS A 254 ? ASN A 235 CYS A 254 1 ? 20 
HELX_P HELX_P14 AB5 SER A 255 ? GLY A 271 ? SER A 255 GLY A 271 1 ? 17 
HELX_P HELX_P15 AB6 PRO A 273 ? ASN A 288 ? PRO A 273 ASN A 288 1 ? 16 
HELX_P HELX_P16 AB7 MET A 289 ? TYR A 307 ? MET A 289 TYR A 307 1 ? 19 
HELX_P HELX_P17 AB8 THR A 312 ? SER A 327 ? THR A 312 SER A 327 1 ? 16 
HELX_P HELX_P18 AB9 MET A 340 ? GLY A 349 ? MET A 340 GLY A 349 1 ? 10 
HELX_P HELX_P19 AC1 GLU A 353 ? GLY A 360 ? GLU A 353 GLY A 360 1 ? 8  
HELX_P HELX_P20 AC2 ILE A 361 ? ASN A 389 ? ILE A 361 ASN A 389 1 ? 29 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_pdbx_entry_details.entry_id                   9BGZ 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_ligand_of_interest     ? 
_pdbx_entry_details.has_protein_modification   N 
# 
_pdbx_validate_torsion.id              1 
_pdbx_validate_torsion.PDB_model_num   1 
_pdbx_validate_torsion.auth_comp_id    ASN 
_pdbx_validate_torsion.auth_asym_id    A 
_pdbx_validate_torsion.auth_seq_id     121 
_pdbx_validate_torsion.PDB_ins_code    ? 
_pdbx_validate_torsion.label_alt_id    ? 
_pdbx_validate_torsion.phi             73.94 
_pdbx_validate_torsion.psi             -6.79 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BGZ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BGZ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.0 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               63865 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       '20 mM HEPES, 100 mM NMDG-Cl' 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Ancestral uncoupled aspartate transporter, apo conditions, high-affinity state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BGZ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             0900 
_em_imaging.nominal_defocus_max             2100 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9BGZ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BGZ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A LEU 101 ? A LEU 101 
2  1 Y 1 A GLY 102 ? A GLY 102 
3  1 Y 1 A GLU 103 ? A GLU 103 
4  1 Y 1 A ILE 104 ? A ILE 104 
5  1 Y 1 A HIS 105 ? A HIS 105 
6  1 Y 1 A GLU 106 ? A GLU 106 
7  1 Y 1 A VAL 107 ? A VAL 107 
8  1 Y 1 A ALA 108 ? A ALA 108 
9  1 Y 1 A HIS 109 ? A HIS 109 
10 1 Y 1 A PRO 110 ? A PRO 110 
11 1 Y 1 A ASN 111 ? A ASN 111 
12 1 Y 1 A ALA 112 ? A ALA 112 
13 1 Y 1 A GLY 329 ? A GLY 329 
14 1 Y 1 A THR 330 ? A THR 330 
15 1 Y 1 A ALA 331 ? A ALA 331 
16 1 Y 1 A GLY 332 ? A GLY 332 
17 1 Y 1 A VAL 333 ? A VAL 333 
18 1 Y 1 A PRO 334 ? A PRO 334 
19 1 Y 1 A GLY 335 ? A GLY 335 
20 1 Y 1 A ALA 336 ? A ALA 336 
21 1 Y 1 A GLU 390 ? A GLU 390 
22 1 Y 1 A LEU 391 ? A LEU 391 
23 1 Y 1 A ASN 392 ? A ASN 392 
24 1 Y 1 A ARG 393 ? A ARG 393 
25 1 Y 1 A GLU 394 ? A GLU 394 
26 1 Y 1 A MET 395 ? A MET 395 
27 1 Y 1 A THR 396 ? A THR 396 
28 1 Y 1 A ALA 397 ? A ALA 397 
29 1 Y 1 A THR 398 ? A THR 398 
30 1 Y 1 A PRO 399 ? A PRO 399 
31 1 Y 1 A LEU 400 ? A LEU 400 
32 1 Y 1 A GLU 401 ? A GLU 401 
33 1 Y 1 A VAL 402 ? A VAL 402 
34 1 Y 1 A LEU 403 ? A LEU 403 
35 1 Y 1 A GLU 404 ? A GLU 404 
36 1 Y 1 A SER 405 ? A SER 405 
37 1 Y 1 A LYS 406 ? A LYS 406 
38 1 Y 1 A THR 407 ? A THR 407 
39 1 Y 1 A ILE 408 ? A ILE 408 
40 1 Y 1 A ALA 409 ? A ALA 409 
41 1 Y 1 A LEU 410 ? A LEU 410 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
PHE N    N N N 247 
PHE CA   C N S 248 
PHE C    C N N 249 
PHE O    O N N 250 
PHE CB   C N N 251 
PHE CG   C Y N 252 
PHE CD1  C Y N 253 
PHE CD2  C Y N 254 
PHE CE1  C Y N 255 
PHE CE2  C Y N 256 
PHE CZ   C Y N 257 
PHE OXT  O N N 258 
PHE H    H N N 259 
PHE H2   H N N 260 
PHE HA   H N N 261 
PHE HB2  H N N 262 
PHE HB3  H N N 263 
PHE HD1  H N N 264 
PHE HD2  H N N 265 
PHE HE1  H N N 266 
PHE HE2  H N N 267 
PHE HZ   H N N 268 
PHE HXT  H N N 269 
PRO N    N N N 270 
PRO CA   C N S 271 
PRO C    C N N 272 
PRO O    O N N 273 
PRO CB   C N N 274 
PRO CG   C N N 275 
PRO CD   C N N 276 
PRO OXT  O N N 277 
PRO H    H N N 278 
PRO HA   H N N 279 
PRO HB2  H N N 280 
PRO HB3  H N N 281 
PRO HG2  H N N 282 
PRO HG3  H N N 283 
PRO HD2  H N N 284 
PRO HD3  H N N 285 
PRO HXT  H N N 286 
SER N    N N N 287 
SER CA   C N S 288 
SER C    C N N 289 
SER O    O N N 290 
SER CB   C N N 291 
SER OG   O N N 292 
SER OXT  O N N 293 
SER H    H N N 294 
SER H2   H N N 295 
SER HA   H N N 296 
SER HB2  H N N 297 
SER HB3  H N N 298 
SER HG   H N N 299 
SER HXT  H N N 300 
THR N    N N N 301 
THR CA   C N S 302 
THR C    C N N 303 
THR O    O N N 304 
THR CB   C N R 305 
THR OG1  O N N 306 
THR CG2  C N N 307 
THR OXT  O N N 308 
THR H    H N N 309 
THR H2   H N N 310 
THR HA   H N N 311 
THR HB   H N N 312 
THR HG1  H N N 313 
THR HG21 H N N 314 
THR HG22 H N N 315 
THR HG23 H N N 316 
THR HXT  H N N 317 
TRP N    N N N 318 
TRP CA   C N S 319 
TRP C    C N N 320 
TRP O    O N N 321 
TRP CB   C N N 322 
TRP CG   C Y N 323 
TRP CD1  C Y N 324 
TRP CD2  C Y N 325 
TRP NE1  N Y N 326 
TRP CE2  C Y N 327 
TRP CE3  C Y N 328 
TRP CZ2  C Y N 329 
TRP CZ3  C Y N 330 
TRP CH2  C Y N 331 
TRP OXT  O N N 332 
TRP H    H N N 333 
TRP H2   H N N 334 
TRP HA   H N N 335 
TRP HB2  H N N 336 
TRP HB3  H N N 337 
TRP HD1  H N N 338 
TRP HE1  H N N 339 
TRP HE3  H N N 340 
TRP HZ2  H N N 341 
TRP HZ3  H N N 342 
TRP HH2  H N N 343 
TRP HXT  H N N 344 
TYR N    N N N 345 
TYR CA   C N S 346 
TYR C    C N N 347 
TYR O    O N N 348 
TYR CB   C N N 349 
TYR CG   C Y N 350 
TYR CD1  C Y N 351 
TYR CD2  C Y N 352 
TYR CE1  C Y N 353 
TYR CE2  C Y N 354 
TYR CZ   C Y N 355 
TYR OH   O N N 356 
TYR OXT  O N N 357 
TYR H    H N N 358 
TYR H2   H N N 359 
TYR HA   H N N 360 
TYR HB2  H N N 361 
TYR HB3  H N N 362 
TYR HD1  H N N 363 
TYR HD2  H N N 364 
TYR HE1  H N N 365 
TYR HE2  H N N 366 
TYR HH   H N N 367 
TYR HXT  H N N 368 
VAL N    N N N 369 
VAL CA   C N S 370 
VAL C    C N N 371 
VAL O    O N N 372 
VAL CB   C N N 373 
VAL CG1  C N N 374 
VAL CG2  C N N 375 
VAL OXT  O N N 376 
VAL H    H N N 377 
VAL H2   H N N 378 
VAL HA   H N N 379 
VAL HB   H N N 380 
VAL HG11 H N N 381 
VAL HG12 H N N 382 
VAL HG13 H N N 383 
VAL HG21 H N N 384 
VAL HG22 H N N 385 
VAL HG23 H N N 386 
VAL HXT  H N N 387 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
PHE N   CA   sing N N 235 
PHE N   H    sing N N 236 
PHE N   H2   sing N N 237 
PHE CA  C    sing N N 238 
PHE CA  CB   sing N N 239 
PHE CA  HA   sing N N 240 
PHE C   O    doub N N 241 
PHE C   OXT  sing N N 242 
PHE CB  CG   sing N N 243 
PHE CB  HB2  sing N N 244 
PHE CB  HB3  sing N N 245 
PHE CG  CD1  doub Y N 246 
PHE CG  CD2  sing Y N 247 
PHE CD1 CE1  sing Y N 248 
PHE CD1 HD1  sing N N 249 
PHE CD2 CE2  doub Y N 250 
PHE CD2 HD2  sing N N 251 
PHE CE1 CZ   doub Y N 252 
PHE CE1 HE1  sing N N 253 
PHE CE2 CZ   sing Y N 254 
PHE CE2 HE2  sing N N 255 
PHE CZ  HZ   sing N N 256 
PHE OXT HXT  sing N N 257 
PRO N   CA   sing N N 258 
PRO N   CD   sing N N 259 
PRO N   H    sing N N 260 
PRO CA  C    sing N N 261 
PRO CA  CB   sing N N 262 
PRO CA  HA   sing N N 263 
PRO C   O    doub N N 264 
PRO C   OXT  sing N N 265 
PRO CB  CG   sing N N 266 
PRO CB  HB2  sing N N 267 
PRO CB  HB3  sing N N 268 
PRO CG  CD   sing N N 269 
PRO CG  HG2  sing N N 270 
PRO CG  HG3  sing N N 271 
PRO CD  HD2  sing N N 272 
PRO CD  HD3  sing N N 273 
PRO OXT HXT  sing N N 274 
SER N   CA   sing N N 275 
SER N   H    sing N N 276 
SER N   H2   sing N N 277 
SER CA  C    sing N N 278 
SER CA  CB   sing N N 279 
SER CA  HA   sing N N 280 
SER C   O    doub N N 281 
SER C   OXT  sing N N 282 
SER CB  OG   sing N N 283 
SER CB  HB2  sing N N 284 
SER CB  HB3  sing N N 285 
SER OG  HG   sing N N 286 
SER OXT HXT  sing N N 287 
THR N   CA   sing N N 288 
THR N   H    sing N N 289 
THR N   H2   sing N N 290 
THR CA  C    sing N N 291 
THR CA  CB   sing N N 292 
THR CA  HA   sing N N 293 
THR C   O    doub N N 294 
THR C   OXT  sing N N 295 
THR CB  OG1  sing N N 296 
THR CB  CG2  sing N N 297 
THR CB  HB   sing N N 298 
THR OG1 HG1  sing N N 299 
THR CG2 HG21 sing N N 300 
THR CG2 HG22 sing N N 301 
THR CG2 HG23 sing N N 302 
THR OXT HXT  sing N N 303 
TRP N   CA   sing N N 304 
TRP N   H    sing N N 305 
TRP N   H2   sing N N 306 
TRP CA  C    sing N N 307 
TRP CA  CB   sing N N 308 
TRP CA  HA   sing N N 309 
TRP C   O    doub N N 310 
TRP C   OXT  sing N N 311 
TRP CB  CG   sing N N 312 
TRP CB  HB2  sing N N 313 
TRP CB  HB3  sing N N 314 
TRP CG  CD1  doub Y N 315 
TRP CG  CD2  sing Y N 316 
TRP CD1 NE1  sing Y N 317 
TRP CD1 HD1  sing N N 318 
TRP CD2 CE2  doub Y N 319 
TRP CD2 CE3  sing Y N 320 
TRP NE1 CE2  sing Y N 321 
TRP NE1 HE1  sing N N 322 
TRP CE2 CZ2  sing Y N 323 
TRP CE3 CZ3  doub Y N 324 
TRP CE3 HE3  sing N N 325 
TRP CZ2 CH2  doub Y N 326 
TRP CZ2 HZ2  sing N N 327 
TRP CZ3 CH2  sing Y N 328 
TRP CZ3 HZ3  sing N N 329 
TRP CH2 HH2  sing N N 330 
TRP OXT HXT  sing N N 331 
TYR N   CA   sing N N 332 
TYR N   H    sing N N 333 
TYR N   H2   sing N N 334 
TYR CA  C    sing N N 335 
TYR CA  CB   sing N N 336 
TYR CA  HA   sing N N 337 
TYR C   O    doub N N 338 
TYR C   OXT  sing N N 339 
TYR CB  CG   sing N N 340 
TYR CB  HB2  sing N N 341 
TYR CB  HB3  sing N N 342 
TYR CG  CD1  doub Y N 343 
TYR CG  CD2  sing Y N 344 
TYR CD1 CE1  sing Y N 345 
TYR CD1 HD1  sing N N 346 
TYR CD2 CE2  doub Y N 347 
TYR CD2 HD2  sing N N 348 
TYR CE1 CZ   doub Y N 349 
TYR CE1 HE1  sing N N 350 
TYR CE2 CZ   sing Y N 351 
TYR CE2 HE2  sing N N 352 
TYR CZ  OH   sing N N 353 
TYR OH  HH   sing N N 354 
TYR OXT HXT  sing N N 355 
VAL N   CA   sing N N 356 
VAL N   H    sing N N 357 
VAL N   H2   sing N N 358 
VAL CA  C    sing N N 359 
VAL CA  CB   sing N N 360 
VAL CA  HA   sing N N 361 
VAL C   O    doub N N 362 
VAL C   OXT  sing N N 363 
VAL CB  CG1  sing N N 364 
VAL CB  CG2  sing N N 365 
VAL CB  HB   sing N N 366 
VAL CG1 HG11 sing N N 367 
VAL CG1 HG12 sing N N 368 
VAL CG1 HG13 sing N N 369 
VAL CG2 HG21 sing N N 370 
VAL CG2 HG22 sing N N 371 
VAL CG2 HG23 sing N N 372 
VAL OXT HXT  sing N N 373 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-19 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BGZ 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-03-12 
_em_admin.title              'Ancestral uncoupled aspartate transporter, apo conditions, high-affinity state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          32630 
_em_entity_assembly_naturalsource.organism             'synthetic construct' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50.29 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'       ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'        ? 2  ? ? 1 ?      ? 
MASKING                    ? 3  ? ? ? ?      ? 
'CTF CORRECTION'           ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'       ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'     ? 6  ? ? ? ?      ? 
'MODEL FITTING'            ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'         ? 8  ? ? ? PHENIX ? 
OTHER                      ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT' ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'   ? 11 1 ? ? ?      ? 
CLASSIFICATION             ? 12 1 ? ? ?      ? 
RECONSTRUCTION             ? 13 1 ? ? ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)' 'United States' R37NS134865 1 
'National Institutes of Health/National Institute of Neurological Disorders and Stroke (NIH/NINDS)' 'United States' F32NS102325 2 
'Howard Hughes Medical Institute (HHMI)'                                                            'United States' ?           3 
# 
_atom_sites.entry_id                    9BGZ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
H 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM 1    N N   . MET A 1 1   ? 123.223 177.338 133.423 1.00 93.20  ? 1   MET A N   1 
ATOM 2    C CA  . MET A 1 1   ? 123.778 177.074 134.781 1.00 92.28  ? 1   MET A CA  1 
ATOM 3    C C   . MET A 1 1   ? 125.227 176.613 134.686 1.00 91.56  ? 1   MET A C   1 
ATOM 4    O O   . MET A 1 1   ? 125.717 176.292 133.604 1.00 91.43  ? 1   MET A O   1 
ATOM 5    C CB  . MET A 1 1   ? 122.939 176.021 135.509 1.00 89.11  ? 1   MET A CB  1 
ATOM 6    C CG  . MET A 1 1   ? 122.068 176.580 136.623 1.00 89.40  ? 1   MET A CG  1 
ATOM 7    S SD  . MET A 1 1   ? 123.017 177.402 137.920 1.00 97.02  ? 1   MET A SD  1 
ATOM 8    C CE  . MET A 1 1   ? 121.816 177.438 139.247 1.00 85.09  ? 1   MET A CE  1 
ATOM 9    N N   . SER A 1 2   ? 125.910 176.583 135.828 1.00 79.60  ? 2   SER A N   1 
ATOM 10   C CA  . SER A 1 2   ? 127.307 176.184 135.873 1.00 80.77  ? 2   SER A CA  1 
ATOM 11   C C   . SER A 1 2   ? 127.584 175.521 137.212 1.00 79.76  ? 2   SER A C   1 
ATOM 12   O O   . SER A 1 2   ? 126.831 175.684 138.175 1.00 82.55  ? 2   SER A O   1 
ATOM 13   C CB  . SER A 1 2   ? 128.243 177.380 135.666 1.00 83.55  ? 2   SER A CB  1 
ATOM 14   O OG  . SER A 1 2   ? 128.425 178.096 136.874 1.00 84.86  ? 2   SER A OG  1 
ATOM 15   N N   . LEU A 1 3   ? 128.678 174.761 137.260 1.00 70.94  ? 3   LEU A N   1 
ATOM 16   C CA  . LEU A 1 3   ? 129.044 174.083 138.498 1.00 74.13  ? 3   LEU A CA  1 
ATOM 17   C C   . LEU A 1 3   ? 129.324 175.090 139.606 1.00 70.52  ? 3   LEU A C   1 
ATOM 18   O O   . LEU A 1 3   ? 128.879 174.916 140.746 1.00 71.54  ? 3   LEU A O   1 
ATOM 19   C CB  . LEU A 1 3   ? 130.261 173.187 138.265 1.00 73.18  ? 3   LEU A CB  1 
ATOM 20   C CG  . LEU A 1 3   ? 130.744 172.395 139.483 1.00 69.41  ? 3   LEU A CG  1 
ATOM 21   C CD1 . LEU A 1 3   ? 129.620 171.551 140.060 1.00 65.22  ? 3   LEU A CD1 1 
ATOM 22   C CD2 . LEU A 1 3   ? 131.934 171.527 139.120 1.00 69.93  ? 3   LEU A CD2 1 
ATOM 23   N N   . TYR A 1 4   ? 130.059 176.157 139.288 1.00 67.44  ? 4   TYR A N   1 
ATOM 24   C CA  . TYR A 1 4   ? 130.407 177.141 140.307 1.00 65.50  ? 4   TYR A CA  1 
ATOM 25   C C   . TYR A 1 4   ? 129.161 177.778 140.902 1.00 69.62  ? 4   TYR A C   1 
ATOM 26   O O   . TYR A 1 4   ? 129.035 177.903 142.125 1.00 78.45  ? 4   TYR A O   1 
ATOM 27   C CB  . TYR A 1 4   ? 131.311 178.217 139.715 1.00 66.83  ? 4   TYR A CB  1 
ATOM 28   C CG  . TYR A 1 4   ? 131.524 179.382 140.649 1.00 67.66  ? 4   TYR A CG  1 
ATOM 29   C CD1 . TYR A 1 4   ? 132.072 179.190 141.907 1.00 65.57  ? 4   TYR A CD1 1 
ATOM 30   C CD2 . TYR A 1 4   ? 131.162 180.668 140.281 1.00 72.35  ? 4   TYR A CD2 1 
ATOM 31   C CE1 . TYR A 1 4   ? 132.267 180.248 142.768 1.00 68.18  ? 4   TYR A CE1 1 
ATOM 32   C CE2 . TYR A 1 4   ? 131.350 181.733 141.137 1.00 75.16  ? 4   TYR A CE2 1 
ATOM 33   C CZ  . TYR A 1 4   ? 131.904 181.517 142.379 1.00 75.49  ? 4   TYR A CZ  1 
ATOM 34   O OH  . TYR A 1 4   ? 132.096 182.573 143.238 1.00 78.27  ? 4   TYR A OH  1 
ATOM 35   N N   . HIS A 1 5   ? 128.224 178.192 140.047 1.00 57.88  ? 5   HIS A N   1 
ATOM 36   C CA  . HIS A 1 5   ? 127.015 178.839 140.543 1.00 59.22  ? 5   HIS A CA  1 
ATOM 37   C C   . HIS A 1 5   ? 126.222 177.896 141.435 1.00 68.50  ? 5   HIS A C   1 
ATOM 38   O O   . HIS A 1 5   ? 125.680 178.312 142.465 1.00 73.80  ? 5   HIS A O   1 
ATOM 39   C CB  . HIS A 1 5   ? 126.164 179.323 139.372 1.00 62.80  ? 5   HIS A CB  1 
ATOM 40   C CG  . HIS A 1 5   ? 126.628 180.620 138.790 1.00 66.90  ? 5   HIS A CG  1 
ATOM 41   N ND1 . HIS A 1 5   ? 127.309 180.699 137.595 1.00 70.24  ? 5   HIS A ND1 1 
ATOM 42   C CD2 . HIS A 1 5   ? 126.513 181.891 139.242 1.00 67.70  ? 5   HIS A CD2 1 
ATOM 43   C CE1 . HIS A 1 5   ? 127.592 181.962 137.334 1.00 67.94  ? 5   HIS A CE1 1 
ATOM 44   N NE2 . HIS A 1 5   ? 127.119 182.706 138.317 1.00 70.02  ? 5   HIS A NE2 1 
ATOM 45   N N   . LYS A 1 6   ? 126.139 176.621 141.056 1.00 67.08  ? 6   LYS A N   1 
ATOM 46   C CA  . LYS A 1 6   ? 125.486 175.643 141.917 1.00 63.92  ? 6   LYS A CA  1 
ATOM 47   C C   . LYS A 1 6   ? 126.214 175.525 143.249 1.00 65.21  ? 6   LYS A C   1 
ATOM 48   O O   . LYS A 1 6   ? 125.585 175.475 144.311 1.00 73.60  ? 6   LYS A O   1 
ATOM 49   C CB  . LYS A 1 6   ? 125.422 174.288 141.214 1.00 64.38  ? 6   LYS A CB  1 
ATOM 50   C CG  . LYS A 1 6   ? 124.497 174.258 140.012 1.00 69.06  ? 6   LYS A CG  1 
ATOM 51   C CD  . LYS A 1 6   ? 124.652 172.966 139.231 1.00 70.47  ? 6   LYS A CD  1 
ATOM 52   C CE  . LYS A 1 6   ? 123.595 172.839 138.152 1.00 72.36  ? 6   LYS A CE  1 
ATOM 53   N NZ  . LYS A 1 6   ? 122.270 172.469 138.716 1.00 80.12  ? 6   LYS A NZ  1 
ATOM 54   N N   . ILE A 1 7   ? 127.548 175.485 143.215 1.00 57.26  ? 7   ILE A N   1 
ATOM 55   C CA  . ILE A 1 7   ? 128.314 175.419 144.457 1.00 50.97  ? 7   ILE A CA  1 
ATOM 56   C C   . ILE A 1 7   ? 128.094 176.683 145.276 1.00 52.92  ? 7   ILE A C   1 
ATOM 57   O O   . ILE A 1 7   ? 127.956 176.631 146.502 1.00 65.12  ? 7   ILE A O   1 
ATOM 58   C CB  . ILE A 1 7   ? 129.808 175.191 144.167 1.00 55.06  ? 7   ILE A CB  1 
ATOM 59   C CG1 . ILE A 1 7   ? 130.022 173.838 143.490 1.00 62.45  ? 7   ILE A CG1 1 
ATOM 60   C CG2 . ILE A 1 7   ? 130.613 175.241 145.457 1.00 53.96  ? 7   ILE A CG2 1 
ATOM 61   C CD1 . ILE A 1 7   ? 131.423 173.639 142.957 1.00 57.38  ? 7   ILE A CD1 1 
ATOM 62   N N   . LEU A 1 8   ? 128.081 177.840 144.615 1.00 56.37  ? 8   LEU A N   1 
ATOM 63   C CA  . LEU A 1 8   ? 127.859 179.094 145.328 1.00 53.73  ? 8   LEU A CA  1 
ATOM 64   C C   . LEU A 1 8   ? 126.466 179.133 145.947 1.00 56.19  ? 8   LEU A C   1 
ATOM 65   O O   . LEU A 1 8   ? 126.291 179.571 147.091 1.00 57.16  ? 8   LEU A O   1 
ATOM 66   C CB  . LEU A 1 8   ? 128.062 180.272 144.376 1.00 59.75  ? 8   LEU A CB  1 
ATOM 67   C CG  . LEU A 1 8   ? 128.037 181.666 144.999 1.00 63.11  ? 8   LEU A CG  1 
ATOM 68   C CD1 . LEU A 1 8   ? 129.111 181.811 146.063 1.00 59.93  ? 8   LEU A CD1 1 
ATOM 69   C CD2 . LEU A 1 8   ? 128.208 182.720 143.921 1.00 58.77  ? 8   LEU A CD2 1 
ATOM 70   N N   . ILE A 1 9   ? 125.459 178.682 145.198 1.00 57.75  ? 9   ILE A N   1 
ATOM 71   C CA  . ILE A 1 9   ? 124.100 178.638 145.730 1.00 58.51  ? 9   ILE A CA  1 
ATOM 72   C C   . ILE A 1 9   ? 124.044 177.718 146.941 1.00 64.33  ? 9   ILE A C   1 
ATOM 73   O O   . ILE A 1 9   ? 123.427 178.042 147.962 1.00 73.11  ? 9   ILE A O   1 
ATOM 74   C CB  . ILE A 1 9   ? 123.111 178.197 144.636 1.00 66.06  ? 9   ILE A CB  1 
ATOM 75   C CG1 . ILE A 1 9   ? 122.602 179.420 143.872 1.00 69.83  ? 9   ILE A CG1 1 
ATOM 76   C CG2 . ILE A 1 9   ? 121.951 177.398 145.243 1.00 61.95  ? 9   ILE A CG2 1 
ATOM 77   C CD1 . ILE A 1 9   ? 121.614 179.102 142.770 1.00 74.24  ? 9   ILE A CD1 1 
ATOM 78   N N   . GLY A 1 10  ? 124.674 176.548 146.838 1.00 56.84  ? 10  GLY A N   1 
ATOM 79   C CA  . GLY A 1 10  ? 124.699 175.635 147.966 1.00 58.96  ? 10  GLY A CA  1 
ATOM 80   C C   . GLY A 1 10  ? 125.390 176.231 149.175 1.00 58.69  ? 10  GLY A C   1 
ATOM 81   O O   . GLY A 1 10  ? 124.924 176.080 150.303 1.00 61.81  ? 10  GLY A O   1 
ATOM 82   N N   . PHE A 1 11  ? 126.510 176.917 148.954 1.00 50.71  ? 11  PHE A N   1 
ATOM 83   C CA  . PHE A 1 11  ? 127.221 177.573 150.045 1.00 44.43  ? 11  PHE A CA  1 
ATOM 84   C C   . PHE A 1 11  ? 126.329 178.591 150.743 1.00 56.97  ? 11  PHE A C   1 
ATOM 85   O O   . PHE A 1 11  ? 126.226 178.606 151.977 1.00 64.12  ? 11  PHE A O   1 
ATOM 86   C CB  . PHE A 1 11  ? 128.481 178.240 149.487 1.00 50.32  ? 11  PHE A CB  1 
ATOM 87   C CG  . PHE A 1 11  ? 129.326 178.928 150.518 1.00 50.67  ? 11  PHE A CG  1 
ATOM 88   C CD1 . PHE A 1 11  ? 128.964 180.164 151.022 1.00 53.34  ? 11  PHE A CD1 1 
ATOM 89   C CD2 . PHE A 1 11  ? 130.501 178.351 150.960 1.00 52.15  ? 11  PHE A CD2 1 
ATOM 90   C CE1 . PHE A 1 11  ? 129.745 180.799 151.961 1.00 55.90  ? 11  PHE A CE1 1 
ATOM 91   C CE2 . PHE A 1 11  ? 131.287 178.984 151.899 1.00 54.29  ? 11  PHE A CE2 1 
ATOM 92   C CZ  . PHE A 1 11  ? 130.909 180.210 152.399 1.00 56.34  ? 11  PHE A CZ  1 
ATOM 93   N N   . VAL A 1 12  ? 125.674 179.454 149.965 1.00 57.62  ? 12  VAL A N   1 
ATOM 94   C CA  . VAL A 1 12  ? 124.847 180.504 150.555 1.00 49.88  ? 12  VAL A CA  1 
ATOM 95   C C   . VAL A 1 12  ? 123.671 179.893 151.307 1.00 52.00  ? 12  VAL A C   1 
ATOM 96   O O   . VAL A 1 12  ? 123.340 180.309 152.425 1.00 59.12  ? 12  VAL A O   1 
ATOM 97   C CB  . VAL A 1 12  ? 124.374 181.486 149.469 1.00 53.09  ? 12  VAL A CB  1 
ATOM 98   C CG1 . VAL A 1 12  ? 123.326 182.434 150.030 1.00 54.42  ? 12  VAL A CG1 1 
ATOM 99   C CG2 . VAL A 1 12  ? 125.557 182.257 148.906 1.00 59.36  ? 12  VAL A CG2 1 
ATOM 100  N N   . LEU A 1 13  ? 123.016 178.900 150.703 1.00 53.09  ? 13  LEU A N   1 
ATOM 101  C CA  . LEU A 1 13  ? 121.881 178.265 151.361 1.00 58.08  ? 13  LEU A CA  1 
ATOM 102  C C   . LEU A 1 13  ? 122.317 177.542 152.627 1.00 63.63  ? 13  LEU A C   1 
ATOM 103  O O   . LEU A 1 13  ? 121.593 177.541 153.627 1.00 72.36  ? 13  LEU A O   1 
ATOM 104  C CB  . LEU A 1 13  ? 121.190 177.299 150.402 1.00 61.73  ? 13  LEU A CB  1 
ATOM 105  C CG  . LEU A 1 13  ? 120.312 177.951 149.334 1.00 60.73  ? 13  LEU A CG  1 
ATOM 106  C CD1 . LEU A 1 13  ? 119.905 176.932 148.285 1.00 62.25  ? 13  LEU A CD1 1 
ATOM 107  C CD2 . LEU A 1 13  ? 119.086 178.586 149.965 1.00 54.82  ? 13  LEU A CD2 1 
ATOM 108  N N   . GLY A 1 14  ? 123.493 176.917 152.605 1.00 65.46  ? 14  GLY A N   1 
ATOM 109  C CA  . GLY A 1 14  ? 123.992 176.269 153.803 1.00 64.28  ? 14  GLY A CA  1 
ATOM 110  C C   . GLY A 1 14  ? 124.274 177.257 154.914 1.00 58.79  ? 14  GLY A C   1 
ATOM 111  O O   . GLY A 1 14  ? 123.962 177.001 156.077 1.00 65.15  ? 14  GLY A O   1 
ATOM 112  N N   . VAL A 1 15  ? 124.861 178.404 154.571 1.00 60.50  ? 15  VAL A N   1 
ATOM 113  C CA  . VAL A 1 15  ? 125.095 179.437 155.577 1.00 61.04  ? 15  VAL A CA  1 
ATOM 114  C C   . VAL A 1 15  ? 123.769 179.907 156.162 1.00 59.80  ? 15  VAL A C   1 
ATOM 115  O O   . VAL A 1 15  ? 123.620 180.052 157.382 1.00 66.85  ? 15  VAL A O   1 
ATOM 116  C CB  . VAL A 1 15  ? 125.891 180.606 154.972 1.00 54.27  ? 15  VAL A CB  1 
ATOM 117  C CG1 . VAL A 1 15  ? 125.804 181.832 155.868 1.00 57.12  ? 15  VAL A CG1 1 
ATOM 118  C CG2 . VAL A 1 15  ? 127.341 180.203 154.752 1.00 55.95  ? 15  VAL A CG2 1 
ATOM 119  N N   . ILE A 1 16  ? 122.782 180.146 155.298 1.00 52.82  ? 16  ILE A N   1 
ATOM 120  C CA  . ILE A 1 16  ? 121.489 180.635 155.768 1.00 54.15  ? 16  ILE A CA  1 
ATOM 121  C C   . ILE A 1 16  ? 120.835 179.609 156.686 1.00 58.62  ? 16  ILE A C   1 
ATOM 122  O O   . ILE A 1 16  ? 120.298 179.950 157.746 1.00 65.43  ? 16  ILE A O   1 
ATOM 123  C CB  . ILE A 1 16  ? 120.584 180.985 154.574 1.00 59.19  ? 16  ILE A CB  1 
ATOM 124  C CG1 . ILE A 1 16  ? 121.048 182.292 153.932 1.00 61.30  ? 16  ILE A CG1 1 
ATOM 125  C CG2 . ILE A 1 16  ? 119.134 181.092 155.015 1.00 60.43  ? 16  ILE A CG2 1 
ATOM 126  C CD1 . ILE A 1 16  ? 120.571 182.475 152.512 1.00 62.69  ? 16  ILE A CD1 1 
ATOM 127  N N   . VAL A 1 17  ? 120.863 178.336 156.289 1.00 57.26  ? 17  VAL A N   1 
ATOM 128  C CA  . VAL A 1 17  ? 120.252 177.289 157.103 1.00 57.47  ? 17  VAL A CA  1 
ATOM 129  C C   . VAL A 1 17  ? 120.970 177.174 158.440 1.00 58.74  ? 17  VAL A C   1 
ATOM 130  O O   . VAL A 1 17  ? 120.338 177.060 159.496 1.00 70.31  ? 17  VAL A O   1 
ATOM 131  C CB  . VAL A 1 17  ? 120.252 175.950 156.345 1.00 60.80  ? 17  VAL A CB  1 
ATOM 132  C CG1 . VAL A 1 17  ? 119.815 174.823 157.264 1.00 58.30  ? 17  VAL A CG1 1 
ATOM 133  C CG2 . VAL A 1 17  ? 119.338 176.028 155.135 1.00 63.81  ? 17  VAL A CG2 1 
ATOM 134  N N   . GLY A 1 18  ? 122.304 177.204 158.417 1.00 65.20  ? 18  GLY A N   1 
ATOM 135  C CA  . GLY A 1 18  ? 123.052 177.146 159.657 1.00 69.94  ? 18  GLY A CA  1 
ATOM 136  C C   . GLY A 1 18  ? 122.724 178.294 160.585 1.00 68.69  ? 18  GLY A C   1 
ATOM 137  O O   . GLY A 1 18  ? 122.666 178.116 161.803 1.00 73.57  ? 18  GLY A O   1 
ATOM 138  N N   . LEU A 1 19  ? 122.500 179.484 160.029 1.00 65.89  ? 19  LEU A N   1 
ATOM 139  C CA  . LEU A 1 19  ? 122.089 180.612 160.858 1.00 61.77  ? 19  LEU A CA  1 
ATOM 140  C C   . LEU A 1 19  ? 120.703 180.379 161.445 1.00 58.44  ? 19  LEU A C   1 
ATOM 141  O O   . LEU A 1 19  ? 120.496 180.519 162.656 1.00 61.28  ? 19  LEU A O   1 
ATOM 142  C CB  . LEU A 1 19  ? 122.116 181.904 160.040 1.00 60.05  ? 19  LEU A CB  1 
ATOM 143  C CG  . LEU A 1 19  ? 123.494 182.425 159.635 1.00 59.14  ? 19  LEU A CG  1 
ATOM 144  C CD1 . LEU A 1 19  ? 123.351 183.585 158.667 1.00 58.51  ? 19  LEU A CD1 1 
ATOM 145  C CD2 . LEU A 1 19  ? 124.289 182.843 160.858 1.00 59.30  ? 19  LEU A CD2 1 
ATOM 146  N N   . ILE A 1 20  ? 119.736 180.021 160.600 1.00 59.51  ? 20  ILE A N   1 
ATOM 147  C CA  . ILE A 1 20  ? 118.350 179.964 161.053 1.00 63.64  ? 20  ILE A CA  1 
ATOM 148  C C   . ILE A 1 20  ? 118.118 178.711 161.893 1.00 69.50  ? 20  ILE A C   1 
ATOM 149  O O   . ILE A 1 20  ? 117.536 178.777 162.982 1.00 72.01  ? 20  ILE A O   1 
ATOM 150  C CB  . ILE A 1 20  ? 117.393 180.047 159.849 1.00 64.48  ? 20  ILE A CB  1 
ATOM 151  C CG1 . ILE A 1 20  ? 116.953 181.494 159.619 1.00 69.46  ? 20  ILE A CG1 1 
ATOM 152  C CG2 . ILE A 1 20  ? 116.133 179.229 160.072 1.00 61.93  ? 20  ILE A CG2 1 
ATOM 153  C CD1 . ILE A 1 20  ? 118.098 182.498 159.606 1.00 69.26  ? 20  ILE A CD1 1 
ATOM 154  N N   . PHE A 1 21  ? 118.571 177.550 161.407 1.00 79.42  ? 21  PHE A N   1 
ATOM 155  C CA  . PHE A 1 21  ? 118.472 176.327 162.203 1.00 77.31  ? 21  PHE A CA  1 
ATOM 156  C C   . PHE A 1 21  ? 119.446 176.325 163.374 1.00 74.58  ? 21  PHE A C   1 
ATOM 157  O O   . PHE A 1 21  ? 119.127 175.782 164.436 1.00 75.23  ? 21  PHE A O   1 
ATOM 158  C CB  . PHE A 1 21  ? 118.716 175.090 161.333 1.00 77.94  ? 21  PHE A CB  1 
ATOM 159  C CG  . PHE A 1 21  ? 117.540 174.693 160.482 1.00 79.15  ? 21  PHE A CG  1 
ATOM 160  C CD1 . PHE A 1 21  ? 117.370 173.372 160.097 1.00 78.97  ? 21  PHE A CD1 1 
ATOM 161  C CD2 . PHE A 1 21  ? 116.599 175.622 160.085 1.00 77.65  ? 21  PHE A CD2 1 
ATOM 162  C CE1 . PHE A 1 21  ? 116.294 172.993 159.319 1.00 78.81  ? 21  PHE A CE1 1 
ATOM 163  C CE2 . PHE A 1 21  ? 115.518 175.249 159.308 1.00 79.49  ? 21  PHE A CE2 1 
ATOM 164  C CZ  . PHE A 1 21  ? 115.366 173.933 158.926 1.00 80.90  ? 21  PHE A CZ  1 
ATOM 165  N N   . GLY A 1 22  ? 120.624 176.914 163.204 1.00 63.05  ? 22  GLY A N   1 
ATOM 166  C CA  . GLY A 1 22  ? 121.569 176.979 164.305 1.00 62.84  ? 22  GLY A CA  1 
ATOM 167  C C   . GLY A 1 22  ? 122.091 175.609 164.682 1.00 65.38  ? 22  GLY A C   1 
ATOM 168  O O   . GLY A 1 22  ? 122.514 174.819 163.831 1.00 69.38  ? 22  GLY A O   1 
ATOM 169  N N   . ASP A 1 23  ? 122.059 175.320 165.984 1.00 83.03  ? 23  ASP A N   1 
ATOM 170  C CA  . ASP A 1 23  ? 122.669 174.103 166.504 1.00 84.05  ? 23  ASP A CA  1 
ATOM 171  C C   . ASP A 1 23  ? 122.048 172.846 165.908 1.00 85.55  ? 23  ASP A C   1 
ATOM 172  O O   . ASP A 1 23  ? 122.724 171.817 165.816 1.00 85.33  ? 23  ASP A O   1 
ATOM 173  C CB  . ASP A 1 23  ? 122.540 174.086 168.030 1.00 84.98  ? 23  ASP A CB  1 
ATOM 174  C CG  . ASP A 1 23  ? 123.132 172.841 168.663 1.00 88.53  ? 23  ASP A CG  1 
ATOM 175  O OD1 . ASP A 1 23  ? 122.945 172.654 169.885 1.00 89.91  ? 23  ASP A OD1 1 
ATOM 176  O OD2 . ASP A 1 23  ? 123.807 172.065 167.960 1.00 89.13  ? 23  ASP A OD2 1 
ATOM 177  N N   . LYS A 1 24  ? 120.787 172.904 165.490 1.00 89.44  ? 24  LYS A N   1 
ATOM 178  C CA  . LYS A 1 24  ? 120.110 171.736 164.940 1.00 87.64  ? 24  LYS A CA  1 
ATOM 179  C C   . LYS A 1 24  ? 120.605 171.357 163.550 1.00 87.35  ? 24  LYS A C   1 
ATOM 180  O O   . LYS A 1 24  ? 120.091 170.394 162.972 1.00 86.42  ? 24  LYS A O   1 
ATOM 181  C CB  . LYS A 1 24  ? 118.602 171.985 164.893 1.00 89.30  ? 24  LYS A CB  1 
ATOM 182  C CG  . LYS A 1 24  ? 117.992 172.318 166.243 1.00 90.51  ? 24  LYS A CG  1 
ATOM 183  C CD  . LYS A 1 24  ? 116.493 172.536 166.135 1.00 93.15  ? 24  LYS A CD  1 
ATOM 184  C CE  . LYS A 1 24  ? 115.883 172.885 167.482 1.00 91.11  ? 24  LYS A CE  1 
ATOM 185  N NZ  . LYS A 1 24  ? 115.902 171.727 168.417 1.00 91.37  ? 24  LYS A NZ  1 
ATOM 186  N N   . ALA A 1 25  ? 121.580 172.081 163.000 1.00 81.89  ? 25  ALA A N   1 
ATOM 187  C CA  . ALA A 1 25  ? 122.099 171.786 161.671 1.00 74.52  ? 25  ALA A CA  1 
ATOM 188  C C   . ALA A 1 25  ? 123.078 170.620 161.654 1.00 73.89  ? 25  ALA A C   1 
ATOM 189  O O   . ALA A 1 25  ? 123.458 170.172 160.568 1.00 75.88  ? 25  ALA A O   1 
ATOM 190  C CB  . ALA A 1 25  ? 122.777 173.027 161.089 1.00 73.91  ? 25  ALA A CB  1 
ATOM 191  N N   . GLU A 1 26  ? 123.498 170.120 162.818 1.00 77.72  ? 26  GLU A N   1 
ATOM 192  C CA  . GLU A 1 26  ? 124.364 168.946 162.847 1.00 78.58  ? 26  GLU A CA  1 
ATOM 193  C C   . GLU A 1 26  ? 123.691 167.727 162.233 1.00 80.78  ? 26  GLU A C   1 
ATOM 194  O O   . GLU A 1 26  ? 124.382 166.776 161.854 1.00 77.02  ? 26  GLU A O   1 
ATOM 195  C CB  . GLU A 1 26  ? 124.787 168.635 164.283 1.00 84.23  ? 26  GLU A CB  1 
ATOM 196  C CG  . GLU A 1 26  ? 125.869 169.551 164.831 1.00 87.43  ? 26  GLU A CG  1 
ATOM 197  C CD  . GLU A 1 26  ? 125.372 170.956 165.093 1.00 90.70  ? 26  GLU A CD  1 
ATOM 198  O OE1 . GLU A 1 26  ? 124.686 171.516 164.212 1.00 90.59  ? 26  GLU A OE1 1 
ATOM 199  O OE2 . GLU A 1 26  ? 125.665 171.500 166.177 1.00 89.57  ? 26  GLU A OE2 1 
ATOM 200  N N   . PHE A 1 27  ? 122.361 167.733 162.131 1.00 85.11  ? 27  PHE A N   1 
ATOM 201  C CA  . PHE A 1 27  ? 121.654 166.629 161.495 1.00 83.15  ? 27  PHE A CA  1 
ATOM 202  C C   . PHE A 1 27  ? 122.065 166.458 160.040 1.00 79.17  ? 27  PHE A C   1 
ATOM 203  O O   . PHE A 1 27  ? 121.886 165.371 159.479 1.00 78.33  ? 27  PHE A O   1 
ATOM 204  C CB  . PHE A 1 27  ? 120.142 166.861 161.629 1.00 83.39  ? 27  PHE A CB  1 
ATOM 205  C CG  . PHE A 1 27  ? 119.305 166.135 160.609 1.00 89.24  ? 27  PHE A CG  1 
ATOM 206  C CD1 . PHE A 1 27  ? 118.600 164.998 160.963 1.00 91.45  ? 27  PHE A CD1 1 
ATOM 207  C CD2 . PHE A 1 27  ? 119.171 166.621 159.317 1.00 86.57  ? 27  PHE A CD2 1 
ATOM 208  C CE1 . PHE A 1 27  ? 117.818 164.333 160.040 1.00 90.38  ? 27  PHE A CE1 1 
ATOM 209  C CE2 . PHE A 1 27  ? 118.391 165.960 158.390 1.00 88.06  ? 27  PHE A CE2 1 
ATOM 210  C CZ  . PHE A 1 27  ? 117.710 164.818 158.753 1.00 90.44  ? 27  PHE A CZ  1 
ATOM 211  N N   . ILE A 1 28  ? 122.620 167.503 159.418 1.00 66.36  ? 28  ILE A N   1 
ATOM 212  C CA  . ILE A 1 28  ? 123.036 167.436 158.019 1.00 64.08  ? 28  ILE A CA  1 
ATOM 213  C C   . ILE A 1 28  ? 124.494 167.023 157.866 1.00 69.46  ? 28  ILE A C   1 
ATOM 214  O O   . ILE A 1 28  ? 124.939 166.761 156.738 1.00 74.30  ? 28  ILE A O   1 
ATOM 215  C CB  . ILE A 1 28  ? 122.784 168.800 157.342 1.00 64.77  ? 28  ILE A CB  1 
ATOM 216  C CG1 . ILE A 1 28  ? 121.282 169.070 157.232 1.00 73.07  ? 28  ILE A CG1 1 
ATOM 217  C CG2 . ILE A 1 28  ? 123.424 168.861 155.970 1.00 65.69  ? 28  ILE A CG2 1 
ATOM 218  C CD1 . ILE A 1 28  ? 120.635 168.493 155.989 1.00 76.52  ? 28  ILE A CD1 1 
ATOM 219  N N   . LYS A 1 29  ? 125.242 166.918 158.962 1.00 67.91  ? 29  LYS A N   1 
ATOM 220  C CA  . LYS A 1 29  ? 126.674 166.634 158.882 1.00 62.63  ? 29  LYS A CA  1 
ATOM 221  C C   . LYS A 1 29  ? 127.000 165.428 158.013 1.00 59.35  ? 29  LYS A C   1 
ATOM 222  O O   . LYS A 1 29  ? 127.957 165.506 157.227 1.00 57.14  ? 29  LYS A O   1 
ATOM 223  C CB  . LYS A 1 29  ? 127.219 166.458 160.307 1.00 68.48  ? 29  LYS A CB  1 
ATOM 224  C CG  . LYS A 1 29  ? 128.570 165.744 160.424 1.00 67.77  ? 29  LYS A CG  1 
ATOM 225  C CD  . LYS A 1 29  ? 129.730 166.711 160.290 1.00 61.13  ? 29  LYS A CD  1 
ATOM 226  C CE  . LYS A 1 29  ? 131.038 166.055 160.692 1.00 63.55  ? 29  LYS A CE  1 
ATOM 227  N NZ  . LYS A 1 29  ? 131.165 165.925 162.169 1.00 65.29  ? 29  LYS A NZ  1 
ATOM 228  N N   . PRO A 1 30  ? 126.282 164.305 158.096 1.00 61.14  ? 30  PRO A N   1 
ATOM 229  C CA  . PRO A 1 30  ? 126.685 163.132 157.303 1.00 59.75  ? 30  PRO A CA  1 
ATOM 230  C C   . PRO A 1 30  ? 126.805 163.415 155.816 1.00 61.57  ? 30  PRO A C   1 
ATOM 231  O O   . PRO A 1 30  ? 127.677 162.844 155.150 1.00 67.24  ? 30  PRO A O   1 
ATOM 232  C CB  . PRO A 1 30  ? 125.573 162.118 157.600 1.00 62.72  ? 30  PRO A CB  1 
ATOM 233  C CG  . PRO A 1 30  ? 125.037 162.518 158.921 1.00 65.43  ? 30  PRO A CG  1 
ATOM 234  C CD  . PRO A 1 30  ? 125.140 164.009 158.978 1.00 66.68  ? 30  PRO A CD  1 
ATOM 235  N N   . LEU A 1 31  ? 125.952 164.285 155.274 1.00 55.23  ? 31  LEU A N   1 
ATOM 236  C CA  . LEU A 1 31  ? 126.008 164.577 153.847 1.00 51.84  ? 31  LEU A CA  1 
ATOM 237  C C   . LEU A 1 31  ? 127.332 165.221 153.460 1.00 53.55  ? 31  LEU A C   1 
ATOM 238  O O   . LEU A 1 31  ? 127.890 164.904 152.405 1.00 60.99  ? 31  LEU A O   1 
ATOM 239  C CB  . LEU A 1 31  ? 124.841 165.479 153.456 1.00 57.02  ? 31  LEU A CB  1 
ATOM 240  C CG  . LEU A 1 31  ? 124.424 165.446 151.988 1.00 61.37  ? 31  LEU A CG  1 
ATOM 241  C CD1 . LEU A 1 31  ? 123.781 164.115 151.649 1.00 62.81  ? 31  LEU A CD1 1 
ATOM 242  C CD2 . LEU A 1 31  ? 123.476 166.593 151.686 1.00 60.58  ? 31  LEU A CD2 1 
ATOM 243  N N   . GLY A 1 32  ? 127.845 166.126 154.289 1.00 55.89  ? 32  GLY A N   1 
ATOM 244  C CA  . GLY A 1 32  ? 129.142 166.725 154.042 1.00 56.30  ? 32  GLY A CA  1 
ATOM 245  C C   . GLY A 1 32  ? 130.271 165.728 154.196 1.00 60.08  ? 32  GLY A C   1 
ATOM 246  O O   . GLY A 1 32  ? 131.254 165.764 153.448 1.00 61.98  ? 32  GLY A O   1 
ATOM 247  N N   . ASP A 1 33  ? 130.137 164.827 155.171 1.00 62.14  ? 33  ASP A N   1 
ATOM 248  C CA  . ASP A 1 33  ? 131.148 163.794 155.358 1.00 50.16  ? 33  ASP A CA  1 
ATOM 249  C C   . ASP A 1 33  ? 131.269 162.922 154.118 1.00 55.86  ? 33  ASP A C   1 
ATOM 250  O O   . ASP A 1 33  ? 132.370 162.501 153.753 1.00 66.64  ? 33  ASP A O   1 
ATOM 251  C CB  . ASP A 1 33  ? 130.810 162.940 156.579 1.00 63.51  ? 33  ASP A CB  1 
ATOM 252  C CG  . ASP A 1 33  ? 130.773 163.744 157.860 1.00 76.69  ? 33  ASP A CG  1 
ATOM 253  O OD1 . ASP A 1 33  ? 130.340 163.195 158.895 1.00 73.86  ? 33  ASP A OD1 1 
ATOM 254  O OD2 . ASP A 1 33  ? 131.175 164.925 157.832 1.00 79.08  ? 33  ASP A OD2 1 
ATOM 255  N N   . ILE A 1 34  ? 130.145 162.634 153.459 1.00 54.49  ? 34  ILE A N   1 
ATOM 256  C CA  . ILE A 1 34  ? 130.188 161.863 152.220 1.00 52.30  ? 34  ILE A CA  1 
ATOM 257  C C   . ILE A 1 34  ? 131.007 162.603 151.172 1.00 59.21  ? 34  ILE A C   1 
ATOM 258  O O   . ILE A 1 34  ? 131.835 162.012 150.468 1.00 71.53  ? 34  ILE A O   1 
ATOM 259  C CB  . ILE A 1 34  ? 128.762 161.574 151.721 1.00 46.10  ? 34  ILE A CB  1 
ATOM 260  C CG1 . ILE A 1 34  ? 128.126 160.463 152.556 1.00 48.38  ? 34  ILE A CG1 1 
ATOM 261  C CG2 . ILE A 1 34  ? 128.776 161.193 150.252 1.00 53.26  ? 34  ILE A CG2 1 
ATOM 262  C CD1 . ILE A 1 34  ? 126.625 160.381 152.419 1.00 56.40  ? 34  ILE A CD1 1 
ATOM 263  N N   . PHE A 1 35  ? 130.781 163.911 151.049 1.00 47.29  ? 35  PHE A N   1 
ATOM 264  C CA  . PHE A 1 35  ? 131.522 164.702 150.074 1.00 39.02  ? 35  PHE A CA  1 
ATOM 265  C C   . PHE A 1 35  ? 133.014 164.691 150.379 1.00 51.25  ? 35  PHE A C   1 
ATOM 266  O O   . PHE A 1 35  ? 133.839 164.524 149.471 1.00 59.34  ? 35  PHE A O   1 
ATOM 267  C CB  . PHE A 1 35  ? 130.980 166.130 150.061 1.00 46.39  ? 35  PHE A CB  1 
ATOM 268  C CG  . PHE A 1 35  ? 131.637 167.022 149.054 1.00 49.48  ? 35  PHE A CG  1 
ATOM 269  C CD1 . PHE A 1 35  ? 131.720 166.647 147.727 1.00 49.70  ? 35  PHE A CD1 1 
ATOM 270  C CD2 . PHE A 1 35  ? 132.162 168.243 149.434 1.00 53.68  ? 35  PHE A CD2 1 
ATOM 271  C CE1 . PHE A 1 35  ? 132.322 167.469 146.799 1.00 55.30  ? 35  PHE A CE1 1 
ATOM 272  C CE2 . PHE A 1 35  ? 132.764 169.069 148.511 1.00 53.64  ? 35  PHE A CE2 1 
ATOM 273  C CZ  . PHE A 1 35  ? 132.842 168.682 147.191 1.00 58.66  ? 35  PHE A CZ  1 
ATOM 274  N N   . LEU A 1 36  ? 133.381 164.861 151.650 1.00 55.83  ? 36  LEU A N   1 
ATOM 275  C CA  . LEU A 1 36  ? 134.793 164.842 152.019 1.00 52.47  ? 36  LEU A CA  1 
ATOM 276  C C   . LEU A 1 36  ? 135.413 163.480 151.736 1.00 50.82  ? 36  LEU A C   1 
ATOM 277  O O   . LEU A 1 36  ? 136.548 163.388 151.255 1.00 54.77  ? 36  LEU A O   1 
ATOM 278  C CB  . LEU A 1 36  ? 134.954 165.208 153.493 1.00 56.65  ? 36  LEU A CB  1 
ATOM 279  C CG  . LEU A 1 36  ? 135.386 166.648 153.764 1.00 58.04  ? 36  LEU A CG  1 
ATOM 280  C CD1 . LEU A 1 36  ? 134.347 167.617 153.242 1.00 59.43  ? 36  LEU A CD1 1 
ATOM 281  C CD2 . LEU A 1 36  ? 135.619 166.861 155.248 1.00 60.73  ? 36  LEU A CD2 1 
ATOM 282  N N   . ARG A 1 37  ? 134.684 162.407 152.043 1.00 52.00  ? 37  ARG A N   1 
ATOM 283  C CA  . ARG A 1 37  ? 135.184 161.065 151.776 1.00 44.47  ? 37  ARG A CA  1 
ATOM 284  C C   . ARG A 1 37  ? 135.435 160.870 150.288 1.00 45.21  ? 37  ARG A C   1 
ATOM 285  O O   . ARG A 1 37  ? 136.477 160.346 149.881 1.00 50.04  ? 37  ARG A O   1 
ATOM 286  C CB  . ARG A 1 37  ? 134.182 160.031 152.288 1.00 45.32  ? 37  ARG A CB  1 
ATOM 287  C CG  . ARG A 1 37  ? 134.077 159.959 153.799 1.00 41.33  ? 37  ARG A CG  1 
ATOM 288  C CD  . ARG A 1 37  ? 135.243 159.209 154.404 1.00 44.74  ? 37  ARG A CD  1 
ATOM 289  N NE  . ARG A 1 37  ? 134.791 158.079 155.207 1.00 45.39  ? 37  ARG A NE  1 
ATOM 290  C CZ  . ARG A 1 37  ? 135.395 156.899 155.265 1.00 56.64  ? 37  ARG A CZ  1 
ATOM 291  N NH1 . ARG A 1 37  ? 136.503 156.651 154.587 1.00 56.70  ? 37  ARG A NH1 1 
ATOM 292  N NH2 . ARG A 1 37  ? 134.873 155.942 156.027 1.00 55.97  ? 37  ARG A NH2 1 
ATOM 293  N N   . LEU A 1 38  ? 134.484 161.299 149.458 1.00 44.55  ? 38  LEU A N   1 
ATOM 294  C CA  . LEU A 1 38  ? 134.648 161.162 148.016 1.00 39.62  ? 38  LEU A CA  1 
ATOM 295  C C   . LEU A 1 38  ? 135.844 161.967 147.527 1.00 46.61  ? 38  LEU A C   1 
ATOM 296  O O   . LEU A 1 38  ? 136.622 161.498 146.690 1.00 51.54  ? 38  LEU A O   1 
ATOM 297  C CB  . LEU A 1 38  ? 133.374 161.603 147.299 1.00 40.50  ? 38  LEU A CB  1 
ATOM 298  C CG  . LEU A 1 38  ? 132.147 160.722 147.523 1.00 43.36  ? 38  LEU A CG  1 
ATOM 299  C CD1 . LEU A 1 38  ? 130.900 161.412 147.006 1.00 45.22  ? 38  LEU A CD1 1 
ATOM 300  C CD2 . LEU A 1 38  ? 132.328 159.378 146.850 1.00 48.02  ? 38  LEU A CD2 1 
ATOM 301  N N   . LEU A 1 39  ? 136.007 163.188 148.039 1.00 51.17  ? 39  LEU A N   1 
ATOM 302  C CA  . LEU A 1 39  ? 137.131 164.017 147.614 1.00 47.21  ? 39  LEU A CA  1 
ATOM 303  C C   . LEU A 1 39  ? 138.459 163.374 147.993 1.00 51.27  ? 39  LEU A C   1 
ATOM 304  O O   . LEU A 1 39  ? 139.403 163.353 147.196 1.00 54.80  ? 39  LEU A O   1 
ATOM 305  C CB  . LEU A 1 39  ? 137.017 165.411 148.231 1.00 46.62  ? 39  LEU A CB  1 
ATOM 306  C CG  . LEU A 1 39  ? 136.045 166.388 147.568 1.00 43.54  ? 39  LEU A CG  1 
ATOM 307  C CD1 . LEU A 1 39  ? 135.989 167.672 148.370 1.00 53.66  ? 39  LEU A CD1 1 
ATOM 308  C CD2 . LEU A 1 39  ? 136.433 166.675 146.128 1.00 42.29  ? 39  LEU A CD2 1 
ATOM 309  N N   . LYS A 1 40  ? 138.551 162.842 149.214 1.00 54.41  ? 40  LYS A N   1 
ATOM 310  C CA  . LYS A 1 40  ? 139.803 162.241 149.661 1.00 52.24  ? 40  LYS A CA  1 
ATOM 311  C C   . LYS A 1 40  ? 140.075 160.920 148.956 1.00 54.88  ? 40  LYS A C   1 
ATOM 312  O O   . LYS A 1 40  ? 141.232 160.501 148.849 1.00 56.49  ? 40  LYS A O   1 
ATOM 313  C CB  . LYS A 1 40  ? 139.771 162.034 151.174 1.00 49.77  ? 40  LYS A CB  1 
ATOM 314  C CG  . LYS A 1 40  ? 139.883 163.320 151.972 1.00 50.80  ? 40  LYS A CG  1 
ATOM 315  C CD  . LYS A 1 40  ? 139.440 163.134 153.416 1.00 59.65  ? 40  LYS A CD  1 
ATOM 316  C CE  . LYS A 1 40  ? 140.335 162.159 154.166 1.00 62.05  ? 40  LYS A CE  1 
ATOM 317  N NZ  . LYS A 1 40  ? 141.695 162.717 154.395 1.00 53.26  ? 40  LYS A NZ  1 
ATOM 318  N N   . MET A 1 41  ? 139.027 160.249 148.476 1.00 52.93  ? 41  MET A N   1 
ATOM 319  C CA  . MET A 1 41  ? 139.201 158.961 147.817 1.00 47.89  ? 41  MET A CA  1 
ATOM 320  C C   . MET A 1 41  ? 140.016 159.063 146.533 1.00 45.60  ? 41  MET A C   1 
ATOM 321  O O   . MET A 1 41  ? 140.528 158.045 146.058 1.00 53.42  ? 41  MET A O   1 
ATOM 322  C CB  . MET A 1 41  ? 137.825 158.355 147.529 1.00 50.13  ? 41  MET A CB  1 
ATOM 323  C CG  . MET A 1 41  ? 137.756 157.443 146.320 1.00 49.36  ? 41  MET A CG  1 
ATOM 324  S SD  . MET A 1 41  ? 136.193 156.555 146.251 1.00 63.92  ? 41  MET A SD  1 
ATOM 325  C CE  . MET A 1 41  ? 135.328 157.502 145.007 1.00 44.15  ? 41  MET A CE  1 
ATOM 326  N N   . ILE A 1 42  ? 140.164 160.262 145.974 1.00 43.83  ? 42  ILE A N   1 
ATOM 327  C CA  . ILE A 1 42  ? 140.790 160.430 144.668 1.00 44.41  ? 42  ILE A CA  1 
ATOM 328  C C   . ILE A 1 42  ? 142.239 160.903 144.751 1.00 47.50  ? 42  ILE A C   1 
ATOM 329  O O   . ILE A 1 42  ? 142.965 160.806 143.751 1.00 56.26  ? 42  ILE A O   1 
ATOM 330  C CB  . ILE A 1 42  ? 139.963 161.416 143.814 1.00 50.05  ? 42  ILE A CB  1 
ATOM 331  C CG1 . ILE A 1 42  ? 138.566 160.856 143.550 1.00 53.94  ? 42  ILE A CG1 1 
ATOM 332  C CG2 . ILE A 1 42  ? 140.661 161.724 142.505 1.00 56.07  ? 42  ILE A CG2 1 
ATOM 333  C CD1 . ILE A 1 42  ? 137.503 161.919 143.447 1.00 51.63  ? 42  ILE A CD1 1 
ATOM 334  N N   . VAL A 1 43  ? 142.687 161.387 145.910 1.00 51.30  ? 43  VAL A N   1 
ATOM 335  C CA  . VAL A 1 43  ? 143.944 162.130 145.972 1.00 45.90  ? 43  VAL A CA  1 
ATOM 336  C C   . VAL A 1 43  ? 145.121 161.248 145.570 1.00 47.47  ? 43  VAL A C   1 
ATOM 337  O O   . VAL A 1 43  ? 145.935 161.623 144.720 1.00 61.33  ? 43  VAL A O   1 
ATOM 338  C CB  . VAL A 1 43  ? 144.144 162.720 147.378 1.00 48.13  ? 43  VAL A CB  1 
ATOM 339  C CG1 . VAL A 1 43  ? 145.418 163.537 147.430 1.00 54.57  ? 43  VAL A CG1 1 
ATOM 340  C CG2 . VAL A 1 43  ? 142.952 163.572 147.766 1.00 56.01  ? 43  VAL A CG2 1 
ATOM 341  N N   . VAL A 1 44  ? 145.230 160.068 146.169 1.00 44.14  ? 44  VAL A N   1 
ATOM 342  C CA  . VAL A 1 44  ? 146.435 159.252 146.026 1.00 49.09  ? 44  VAL A CA  1 
ATOM 343  C C   . VAL A 1 44  ? 146.607 158.815 144.574 1.00 51.03  ? 44  VAL A C   1 
ATOM 344  O O   . VAL A 1 44  ? 147.617 159.171 143.943 1.00 48.50  ? 44  VAL A O   1 
ATOM 345  C CB  . VAL A 1 44  ? 146.402 158.038 146.968 1.00 57.55  ? 44  VAL A CB  1 
ATOM 346  C CG1 . VAL A 1 44  ? 147.561 157.108 146.668 1.00 56.95  ? 44  VAL A CG1 1 
ATOM 347  C CG2 . VAL A 1 44  ? 146.443 158.488 148.418 1.00 55.73  ? 44  VAL A CG2 1 
ATOM 348  N N   . PRO A 1 45  ? 145.681 158.036 144.005 1.00 48.97  ? 45  PRO A N   1 
ATOM 349  C CA  . PRO A 1 45  ? 145.869 157.611 142.609 1.00 49.04  ? 45  PRO A CA  1 
ATOM 350  C C   . PRO A 1 45  ? 145.983 158.779 141.651 1.00 45.81  ? 45  PRO A C   1 
ATOM 351  O O   . PRO A 1 45  ? 146.802 158.744 140.724 1.00 45.30  ? 45  PRO A O   1 
ATOM 352  C CB  . PRO A 1 45  ? 144.624 156.759 142.332 1.00 38.36  ? 45  PRO A CB  1 
ATOM 353  C CG  . PRO A 1 45  ? 143.619 157.214 143.311 1.00 34.69  ? 45  PRO A CG  1 
ATOM 354  C CD  . PRO A 1 45  ? 144.376 157.603 144.534 1.00 39.63  ? 45  PRO A CD  1 
ATOM 355  N N   . LEU A 1 46  ? 145.189 159.828 141.864 1.00 45.16  ? 46  LEU A N   1 
ATOM 356  C CA  . LEU A 1 46  ? 145.287 161.007 141.015 1.00 41.97  ? 46  LEU A CA  1 
ATOM 357  C C   . LEU A 1 46  ? 146.671 161.625 141.116 1.00 51.51  ? 46  LEU A C   1 
ATOM 358  O O   . LEU A 1 46  ? 147.291 161.954 140.101 1.00 64.04  ? 46  LEU A O   1 
ATOM 359  C CB  . LEU A 1 46  ? 144.217 162.025 141.402 1.00 45.75  ? 46  LEU A CB  1 
ATOM 360  C CG  . LEU A 1 46  ? 144.231 163.341 140.622 1.00 44.70  ? 46  LEU A CG  1 
ATOM 361  C CD1 . LEU A 1 46  ? 143.905 163.104 139.162 1.00 50.47  ? 46  LEU A CD1 1 
ATOM 362  C CD2 . LEU A 1 46  ? 143.256 164.325 141.233 1.00 43.47  ? 46  LEU A CD2 1 
ATOM 363  N N   . VAL A 1 47  ? 147.179 161.778 142.338 1.00 46.46  ? 47  VAL A N   1 
ATOM 364  C CA  . VAL A 1 47  ? 148.490 162.393 142.525 1.00 39.14  ? 47  VAL A CA  1 
ATOM 365  C C   . VAL A 1 47  ? 149.552 161.592 141.786 1.00 45.87  ? 47  VAL A C   1 
ATOM 366  O O   . VAL A 1 47  ? 150.340 162.137 141.003 1.00 54.74  ? 47  VAL A O   1 
ATOM 367  C CB  . VAL A 1 47  ? 148.818 162.510 144.023 1.00 51.77  ? 47  VAL A CB  1 
ATOM 368  C CG1 . VAL A 1 47  ? 150.314 162.692 144.235 1.00 47.20  ? 47  VAL A CG1 1 
ATOM 369  C CG2 . VAL A 1 47  ? 148.041 163.654 144.647 1.00 57.16  ? 47  VAL A CG2 1 
ATOM 370  N N   . PHE A 1 48  ? 149.577 160.279 142.012 1.00 51.98  ? 48  PHE A N   1 
ATOM 371  C CA  . PHE A 1 48  ? 150.617 159.455 141.408 1.00 46.57  ? 48  PHE A CA  1 
ATOM 372  C C   . PHE A 1 48  ? 150.528 159.494 139.888 1.00 49.59  ? 48  PHE A C   1 
ATOM 373  O O   . PHE A 1 48  ? 151.525 159.748 139.198 1.00 52.81  ? 48  PHE A O   1 
ATOM 374  C CB  . PHE A 1 48  ? 150.510 158.017 141.913 1.00 40.92  ? 48  PHE A CB  1 
ATOM 375  C CG  . PHE A 1 48  ? 151.674 157.156 141.521 1.00 45.43  ? 48  PHE A CG  1 
ATOM 376  C CD1 . PHE A 1 48  ? 152.895 157.300 142.147 1.00 47.54  ? 48  PHE A CD1 1 
ATOM 377  C CD2 . PHE A 1 48  ? 151.550 156.215 140.518 1.00 45.41  ? 48  PHE A CD2 1 
ATOM 378  C CE1 . PHE A 1 48  ? 153.966 156.516 141.788 1.00 42.73  ? 48  PHE A CE1 1 
ATOM 379  C CE2 . PHE A 1 48  ? 152.620 155.429 140.155 1.00 49.26  ? 48  PHE A CE2 1 
ATOM 380  C CZ  . PHE A 1 48  ? 153.828 155.580 140.790 1.00 50.01  ? 48  PHE A CZ  1 
ATOM 381  N N   . SER A 1 49  ? 149.335 159.240 139.345 1.00 53.00  ? 49  SER A N   1 
ATOM 382  C CA  . SER A 1 49  ? 149.181 159.187 137.897 1.00 41.49  ? 49  SER A CA  1 
ATOM 383  C C   . SER A 1 49  ? 149.535 160.522 137.262 1.00 36.15  ? 49  SER A C   1 
ATOM 384  O O   . SER A 1 49  ? 150.242 160.574 136.250 1.00 44.28  ? 49  SER A O   1 
ATOM 385  C CB  . SER A 1 49  ? 147.750 158.787 137.543 1.00 47.77  ? 49  SER A CB  1 
ATOM 386  O OG  . SER A 1 49  ? 147.303 157.721 138.360 1.00 56.86  ? 49  SER A OG  1 
ATOM 387  N N   . THR A 1 50  ? 149.051 161.620 137.846 1.00 35.56  ? 50  THR A N   1 
ATOM 388  C CA  . THR A 1 50  ? 149.294 162.932 137.265 1.00 36.61  ? 50  THR A CA  1 
ATOM 389  C C   . THR A 1 50  ? 150.773 163.280 137.303 1.00 48.24  ? 50  THR A C   1 
ATOM 390  O O   . THR A 1 50  ? 151.320 163.792 136.324 1.00 57.20  ? 50  THR A O   1 
ATOM 391  C CB  . THR A 1 50  ? 148.475 163.989 138.001 1.00 42.99  ? 50  THR A CB  1 
ATOM 392  O OG1 . THR A 1 50  ? 148.700 163.878 139.411 1.00 56.77  ? 50  THR A OG1 1 
ATOM 393  C CG2 . THR A 1 50  ? 146.996 163.807 137.711 1.00 47.64  ? 50  THR A CG2 1 
ATOM 394  N N   . ILE A 1 51  ? 151.447 163.012 138.424 1.00 45.34  ? 51  ILE A N   1 
ATOM 395  C CA  . ILE A 1 51  ? 152.869 163.334 138.505 1.00 39.02  ? 51  ILE A CA  1 
ATOM 396  C C   . ILE A 1 51  ? 153.653 162.514 137.490 1.00 46.45  ? 51  ILE A C   1 
ATOM 397  O O   . ILE A 1 51  ? 154.518 163.036 136.775 1.00 50.94  ? 51  ILE A O   1 
ATOM 398  C CB  . ILE A 1 51  ? 153.394 163.114 139.934 1.00 43.53  ? 51  ILE A CB  1 
ATOM 399  C CG1 . ILE A 1 51  ? 152.857 164.202 140.863 1.00 50.82  ? 51  ILE A CG1 1 
ATOM 400  C CG2 . ILE A 1 51  ? 154.915 163.115 139.943 1.00 38.35  ? 51  ILE A CG2 1 
ATOM 401  C CD1 . ILE A 1 51  ? 153.098 163.932 142.328 1.00 53.17  ? 51  ILE A CD1 1 
ATOM 402  N N   . VAL A 1 52  ? 153.358 161.216 137.405 1.00 51.61  ? 52  VAL A N   1 
ATOM 403  C CA  . VAL A 1 52  ? 154.102 160.353 136.494 1.00 34.71  ? 52  VAL A CA  1 
ATOM 404  C C   . VAL A 1 52  ? 153.896 160.802 135.053 1.00 48.36  ? 52  VAL A C   1 
ATOM 405  O O   . VAL A 1 52  ? 154.853 160.921 134.279 1.00 57.36  ? 52  VAL A O   1 
ATOM 406  C CB  . VAL A 1 52  ? 153.690 158.885 136.693 1.00 34.76  ? 52  VAL A CB  1 
ATOM 407  C CG1 . VAL A 1 52  ? 154.272 158.018 135.594 1.00 47.74  ? 52  VAL A CG1 1 
ATOM 408  C CG2 . VAL A 1 52  ? 154.139 158.395 138.056 1.00 44.06  ? 52  VAL A CG2 1 
ATOM 409  N N   . THR A 1 53  ? 152.645 161.069 134.670 1.00 49.30  ? 53  THR A N   1 
ATOM 410  C CA  . THR A 1 53  ? 152.372 161.442 133.286 1.00 49.22  ? 53  THR A CA  1 
ATOM 411  C C   . THR A 1 53  ? 152.900 162.836 132.969 1.00 61.17  ? 53  THR A C   1 
ATOM 412  O O   . THR A 1 53  ? 153.306 163.105 131.833 1.00 68.38  ? 53  THR A O   1 
ATOM 413  C CB  . THR A 1 53  ? 150.873 161.355 133.003 1.00 49.10  ? 53  THR A CB  1 
ATOM 414  O OG1 . THR A 1 53  ? 150.651 161.393 131.589 1.00 66.11  ? 53  THR A OG1 1 
ATOM 415  C CG2 . THR A 1 53  ? 150.130 162.502 133.653 1.00 54.91  ? 53  THR A CG2 1 
ATOM 416  N N   . GLY A 1 54  ? 152.893 163.741 133.948 1.00 50.35  ? 54  GLY A N   1 
ATOM 417  C CA  . GLY A 1 54  ? 153.448 165.063 133.719 1.00 47.69  ? 54  GLY A CA  1 
ATOM 418  C C   . GLY A 1 54  ? 154.950 165.031 133.517 1.00 54.70  ? 54  GLY A C   1 
ATOM 419  O O   . GLY A 1 54  ? 155.481 165.685 132.615 1.00 65.03  ? 54  GLY A O   1 
ATOM 420  N N   . ILE A 1 55  ? 155.659 164.271 134.354 1.00 45.19  ? 55  ILE A N   1 
ATOM 421  C CA  . ILE A 1 55  ? 157.109 164.190 134.207 1.00 38.73  ? 55  ILE A CA  1 
ATOM 422  C C   . ILE A 1 55  ? 157.468 163.443 132.931 1.00 37.31  ? 55  ILE A C   1 
ATOM 423  O O   . ILE A 1 55  ? 158.434 163.790 132.242 1.00 49.08  ? 55  ILE A O   1 
ATOM 424  C CB  . ILE A 1 55  ? 157.743 163.539 135.448 1.00 35.40  ? 55  ILE A CB  1 
ATOM 425  C CG1 . ILE A 1 55  ? 157.535 164.435 136.669 1.00 41.30  ? 55  ILE A CG1 1 
ATOM 426  C CG2 . ILE A 1 55  ? 159.227 163.310 135.225 1.00 42.87  ? 55  ILE A CG2 1 
ATOM 427  C CD1 . ILE A 1 55  ? 157.857 163.768 137.976 1.00 44.81  ? 55  ILE A CD1 1 
ATOM 428  N N   . ALA A 1 56  ? 156.700 162.406 132.594 1.00 36.96  ? 56  ALA A N   1 
ATOM 429  C CA  . ALA A 1 56  ? 156.947 161.684 131.352 1.00 42.00  ? 56  ALA A CA  1 
ATOM 430  C C   . ALA A 1 56  ? 156.768 162.593 130.144 1.00 51.50  ? 56  ALA A C   1 
ATOM 431  O O   . ALA A 1 56  ? 157.541 162.522 129.182 1.00 51.47  ? 56  ALA A O   1 
ATOM 432  C CB  . ALA A 1 56  ? 156.015 160.478 131.255 1.00 45.07  ? 56  ALA A CB  1 
ATOM 433  N N   . SER A 1 57  ? 155.749 163.453 130.176 1.00 59.56  ? 57  SER A N   1 
ATOM 434  C CA  . SER A 1 57  ? 155.469 164.316 129.034 1.00 58.63  ? 57  SER A CA  1 
ATOM 435  C C   . SER A 1 57  ? 156.617 165.280 128.769 1.00 61.63  ? 57  SER A C   1 
ATOM 436  O O   . SER A 1 57  ? 156.939 165.566 127.611 1.00 67.81  ? 57  SER A O   1 
ATOM 437  C CB  . SER A 1 57  ? 154.170 165.084 129.269 1.00 63.61  ? 57  SER A CB  1 
ATOM 438  O OG  . SER A 1 57  ? 153.095 164.192 129.507 1.00 64.29  ? 57  SER A OG  1 
ATOM 439  N N   . MET A 1 58  ? 157.240 165.801 129.829 1.00 59.44  ? 58  MET A N   1 
ATOM 440  C CA  . MET A 1 58  ? 158.316 166.771 129.656 1.00 59.91  ? 58  MET A CA  1 
ATOM 441  C C   . MET A 1 58  ? 159.381 166.242 128.705 1.00 72.19  ? 58  MET A C   1 
ATOM 442  O O   . MET A 1 58  ? 159.785 166.924 127.757 1.00 74.02  ? 58  MET A O   1 
ATOM 443  C CB  . MET A 1 58  ? 158.943 167.110 131.009 1.00 60.82  ? 58  MET A CB  1 
ATOM 444  C CG  . MET A 1 58  ? 158.367 168.338 131.684 1.00 64.18  ? 58  MET A CG  1 
ATOM 445  S SD  . MET A 1 58  ? 158.669 168.323 133.459 1.00 88.77  ? 58  MET A SD  1 
ATOM 446  C CE  . MET A 1 58  ? 157.196 169.130 134.077 1.00 69.64  ? 58  MET A CE  1 
ATOM 447  N N   . GLY A 1 59  ? 159.853 165.020 128.950 1.00 73.36  ? 59  GLY A N   1 
ATOM 448  C CA  . GLY A 1 59  ? 160.902 164.428 128.153 1.00 66.80  ? 59  GLY A CA  1 
ATOM 449  C C   . GLY A 1 59  ? 162.292 164.949 128.439 1.00 73.74  ? 59  GLY A C   1 
ATOM 450  O O   . GLY A 1 59  ? 163.271 164.292 128.067 1.00 73.50  ? 59  GLY A O   1 
ATOM 451  N N   . ASP A 1 60  ? 162.415 166.108 129.086 1.00 83.01  ? 60  ASP A N   1 
ATOM 452  C CA  . ASP A 1 60  ? 163.706 166.703 129.419 1.00 84.08  ? 60  ASP A CA  1 
ATOM 453  C C   . ASP A 1 60  ? 163.844 166.701 130.938 1.00 82.12  ? 60  ASP A C   1 
ATOM 454  O O   . ASP A 1 60  ? 163.186 167.478 131.633 1.00 81.40  ? 60  ASP A O   1 
ATOM 455  C CB  . ASP A 1 60  ? 163.813 168.114 128.849 1.00 84.53  ? 60  ASP A CB  1 
ATOM 456  C CG  . ASP A 1 60  ? 165.238 168.630 128.826 1.00 90.22  ? 60  ASP A CG  1 
ATOM 457  O OD1 . ASP A 1 60  ? 165.424 169.857 128.690 1.00 86.77  ? 60  ASP A OD1 1 
ATOM 458  O OD2 . ASP A 1 60  ? 166.174 167.811 128.946 1.00 88.80  ? 60  ASP A OD2 1 
ATOM 459  N N   . VAL A 1 61  ? 164.703 165.820 131.453 1.00 68.39  ? 61  VAL A N   1 
ATOM 460  C CA  . VAL A 1 61  ? 164.900 165.742 132.897 1.00 67.62  ? 61  VAL A CA  1 
ATOM 461  C C   . VAL A 1 61  ? 165.497 167.040 133.421 1.00 61.75  ? 61  VAL A C   1 
ATOM 462  O O   . VAL A 1 61  ? 165.104 167.537 134.484 1.00 66.69  ? 61  VAL A O   1 
ATOM 463  C CB  . VAL A 1 61  ? 165.778 164.526 133.251 1.00 64.44  ? 61  VAL A CB  1 
ATOM 464  C CG1 . VAL A 1 61  ? 166.480 164.734 134.588 1.00 61.41  ? 61  VAL A CG1 1 
ATOM 465  C CG2 . VAL A 1 61  ? 164.936 163.261 133.279 1.00 55.49  ? 61  VAL A CG2 1 
ATOM 466  N N   . LYS A 1 62  ? 166.458 167.609 132.691 1.00 59.81  ? 62  LYS A N   1 
ATOM 467  C CA  . LYS A 1 62  ? 167.065 168.866 133.117 1.00 69.96  ? 62  LYS A CA  1 
ATOM 468  C C   . LYS A 1 62  ? 166.006 169.936 133.336 1.00 74.12  ? 62  LYS A C   1 
ATOM 469  O O   . LYS A 1 62  ? 166.116 170.753 134.258 1.00 72.07  ? 62  LYS A O   1 
ATOM 470  C CB  . LYS A 1 62  ? 168.085 169.334 132.079 1.00 74.36  ? 62  LYS A CB  1 
ATOM 471  C CG  . LYS A 1 62  ? 169.531 169.072 132.466 1.00 78.43  ? 62  LYS A CG  1 
ATOM 472  C CD  . LYS A 1 62  ? 170.452 169.140 131.253 1.00 78.71  ? 62  LYS A CD  1 
ATOM 473  C CE  . LYS A 1 62  ? 171.801 168.477 131.508 1.00 79.98  ? 62  LYS A CE  1 
ATOM 474  N NZ  . LYS A 1 62  ? 171.692 167.130 132.136 1.00 78.45  ? 62  LYS A NZ  1 
ATOM 475  N N   . LYS A 1 63  ? 164.970 169.946 132.498 1.00 77.34  ? 63  LYS A N   1 
ATOM 476  C CA  . LYS A 1 63  ? 163.896 170.918 132.661 1.00 70.21  ? 63  LYS A CA  1 
ATOM 477  C C   . LYS A 1 63  ? 163.202 170.748 134.005 1.00 71.34  ? 63  LYS A C   1 
ATOM 478  O O   . LYS A 1 63  ? 162.907 171.734 134.689 1.00 81.29  ? 63  LYS A O   1 
ATOM 479  C CB  . LYS A 1 63  ? 162.895 170.774 131.516 1.00 70.44  ? 63  LYS A CB  1 
ATOM 480  C CG  . LYS A 1 63  ? 161.748 171.763 131.555 1.00 73.30  ? 63  LYS A CG  1 
ATOM 481  C CD  . LYS A 1 63  ? 160.854 171.596 130.341 1.00 80.03  ? 63  LYS A CD  1 
ATOM 482  C CE  . LYS A 1 63  ? 159.646 172.510 130.402 1.00 76.76  ? 63  LYS A CE  1 
ATOM 483  N NZ  . LYS A 1 63  ? 158.846 172.442 129.150 1.00 79.27  ? 63  LYS A NZ  1 
ATOM 484  N N   . LEU A 1 64  ? 162.940 169.503 134.406 1.00 59.74  ? 64  LEU A N   1 
ATOM 485  C CA  . LEU A 1 64  ? 162.259 169.263 135.674 1.00 59.65  ? 64  LEU A CA  1 
ATOM 486  C C   . LEU A 1 64  ? 163.049 169.841 136.840 1.00 68.82  ? 64  LEU A C   1 
ATOM 487  O O   . LEU A 1 64  ? 162.464 170.369 137.791 1.00 75.55  ? 64  LEU A O   1 
ATOM 488  C CB  . LEU A 1 64  ? 162.032 167.762 135.868 1.00 58.88  ? 64  LEU A CB  1 
ATOM 489  C CG  . LEU A 1 64  ? 161.082 167.295 136.980 1.00 64.29  ? 64  LEU A CG  1 
ATOM 490  C CD1 . LEU A 1 64  ? 161.749 167.356 138.344 1.00 66.97  ? 64  LEU A CD1 1 
ATOM 491  C CD2 . LEU A 1 64  ? 159.791 168.096 136.993 1.00 63.03  ? 64  LEU A CD2 1 
ATOM 492  N N   . GLY A 1 65  ? 164.377 169.744 136.791 1.00 68.93  ? 65  GLY A N   1 
ATOM 493  C CA  . GLY A 1 65  ? 165.182 170.280 137.876 1.00 63.40  ? 65  GLY A CA  1 
ATOM 494  C C   . GLY A 1 65  ? 164.991 171.773 138.057 1.00 67.82  ? 65  GLY A C   1 
ATOM 495  O O   . GLY A 1 65  ? 164.868 172.262 139.184 1.00 73.59  ? 65  GLY A O   1 
ATOM 496  N N   . ARG A 1 66  ? 164.964 172.519 136.951 1.00 67.38  ? 66  ARG A N   1 
ATOM 497  C CA  . ARG A 1 66  ? 164.749 173.959 137.038 1.00 69.47  ? 66  ARG A CA  1 
ATOM 498  C C   . ARG A 1 66  ? 163.386 174.270 137.638 1.00 70.11  ? 66  ARG A C   1 
ATOM 499  O O   . ARG A 1 66  ? 163.258 175.151 138.497 1.00 78.81  ? 66  ARG A O   1 
ATOM 500  C CB  . ARG A 1 66  ? 164.877 174.593 135.654 1.00 68.23  ? 66  ARG A CB  1 
ATOM 501  C CG  . ARG A 1 66  ? 166.204 174.341 134.972 1.00 71.12  ? 66  ARG A CG  1 
ATOM 502  C CD  . ARG A 1 66  ? 166.371 175.247 133.768 1.00 73.53  ? 66  ARG A CD  1 
ATOM 503  N NE  . ARG A 1 66  ? 165.240 175.145 132.851 1.00 73.81  ? 66  ARG A NE  1 
ATOM 504  C CZ  . ARG A 1 66  ? 165.267 174.538 131.672 1.00 74.03  ? 66  ARG A CZ  1 
ATOM 505  N NH1 . ARG A 1 66  ? 166.362 173.949 131.216 1.00 72.52  ? 66  ARG A NH1 1 
ATOM 506  N NH2 . ARG A 1 66  ? 164.165 174.519 130.929 1.00 73.80  ? 66  ARG A NH2 1 
ATOM 507  N N   . ILE A 1 67  ? 162.349 173.561 137.189 1.00 60.79  ? 67  ILE A N   1 
ATOM 508  C CA  . ILE A 1 67  ? 161.007 173.804 137.711 1.00 63.53  ? 67  ILE A CA  1 
ATOM 509  C C   . ILE A 1 67  ? 160.971 173.519 139.204 1.00 65.52  ? 67  ILE A C   1 
ATOM 510  O O   . ILE A 1 67  ? 160.392 174.281 139.984 1.00 76.13  ? 67  ILE A O   1 
ATOM 511  C CB  . ILE A 1 67  ? 159.970 172.961 136.948 1.00 67.48  ? 67  ILE A CB  1 
ATOM 512  C CG1 . ILE A 1 67  ? 160.043 173.274 135.454 1.00 70.04  ? 67  ILE A CG1 1 
ATOM 513  C CG2 . ILE A 1 67  ? 158.560 173.238 137.464 1.00 67.91  ? 67  ILE A CG2 1 
ATOM 514  C CD1 . ILE A 1 67  ? 158.805 172.885 134.673 1.00 72.51  ? 67  ILE A CD1 1 
ATOM 515  N N   . GLY A 1 68  ? 161.587 172.415 139.625 1.00 56.83  ? 68  GLY A N   1 
ATOM 516  C CA  . GLY A 1 68  ? 161.590 172.083 141.039 1.00 59.30  ? 68  GLY A CA  1 
ATOM 517  C C   . GLY A 1 68  ? 162.310 173.124 141.873 1.00 68.08  ? 68  GLY A C   1 
ATOM 518  O O   . GLY A 1 68  ? 161.822 173.543 142.926 1.00 71.32  ? 68  GLY A O   1 
ATOM 519  N N   . ALA A 1 69  ? 163.485 173.556 141.411 1.00 71.18  ? 69  ALA A N   1 
ATOM 520  C CA  . ALA A 1 69  ? 164.241 174.561 142.151 1.00 67.97  ? 69  ALA A CA  1 
ATOM 521  C C   . ALA A 1 69  ? 163.456 175.860 142.260 1.00 67.60  ? 69  ALA A C   1 
ATOM 522  O O   . ALA A 1 69  ? 163.359 176.454 143.341 1.00 75.05  ? 69  ALA A O   1 
ATOM 523  C CB  . ALA A 1 69  ? 165.590 174.802 141.475 1.00 65.45  ? 69  ALA A CB  1 
ATOM 524  N N   . LYS A 1 70  ? 162.880 176.315 141.146 1.00 66.81  ? 70  LYS A N   1 
ATOM 525  C CA  . LYS A 1 70  ? 162.122 177.560 141.165 1.00 66.32  ? 70  LYS A CA  1 
ATOM 526  C C   . LYS A 1 70  ? 160.902 177.440 142.068 1.00 65.37  ? 70  LYS A C   1 
ATOM 527  O O   . LYS A 1 70  ? 160.576 178.369 142.815 1.00 74.43  ? 70  LYS A O   1 
ATOM 528  C CB  . LYS A 1 70  ? 161.713 177.943 139.744 1.00 64.01  ? 70  LYS A CB  1 
ATOM 529  C CG  . LYS A 1 70  ? 162.896 178.276 138.847 1.00 63.42  ? 70  LYS A CG  1 
ATOM 530  C CD  . LYS A 1 70  ? 162.676 177.845 137.405 1.00 63.59  ? 70  LYS A CD  1 
ATOM 531  C CE  . LYS A 1 70  ? 162.145 178.980 136.551 1.00 67.40  ? 70  LYS A CE  1 
ATOM 532  N NZ  . LYS A 1 70  ? 162.539 178.818 135.129 1.00 77.72  ? 70  LYS A NZ  1 
ATOM 533  N N   . THR A 1 71  ? 160.215 176.299 142.016 1.00 61.51  ? 71  THR A N   1 
ATOM 534  C CA  . THR A 1 71  ? 159.036 176.103 142.849 1.00 66.42  ? 71  THR A CA  1 
ATOM 535  C C   . THR A 1 71  ? 159.400 176.122 144.328 1.00 71.31  ? 71  THR A C   1 
ATOM 536  O O   . THR A 1 71  ? 158.705 176.741 145.141 1.00 72.50  ? 71  THR A O   1 
ATOM 537  C CB  . THR A 1 71  ? 158.355 174.787 142.477 1.00 69.02  ? 71  THR A CB  1 
ATOM 538  O OG1 . THR A 1 71  ? 157.959 174.821 141.102 1.00 70.08  ? 71  THR A OG1 1 
ATOM 539  C CG2 . THR A 1 71  ? 157.139 174.547 143.345 1.00 67.11  ? 71  THR A CG2 1 
ATOM 540  N N   . LEU A 1 72  ? 160.488 175.446 144.698 1.00 67.58  ? 72  LEU A N   1 
ATOM 541  C CA  . LEU A 1 72  ? 160.903 175.435 146.098 1.00 66.84  ? 72  LEU A CA  1 
ATOM 542  C C   . LEU A 1 72  ? 161.298 176.831 146.561 1.00 75.83  ? 72  LEU A C   1 
ATOM 543  O O   . LEU A 1 72  ? 160.947 177.257 147.670 1.00 77.85  ? 72  LEU A O   1 
ATOM 544  C CB  . LEU A 1 72  ? 162.061 174.457 146.294 1.00 64.30  ? 72  LEU A CB  1 
ATOM 545  C CG  . LEU A 1 72  ? 161.688 173.086 146.858 1.00 69.47  ? 72  LEU A CG  1 
ATOM 546  C CD1 . LEU A 1 72  ? 160.533 172.465 146.087 1.00 75.06  ? 72  LEU A CD1 1 
ATOM 547  C CD2 . LEU A 1 72  ? 162.898 172.168 146.848 1.00 72.13  ? 72  LEU A CD2 1 
ATOM 548  N N   . ILE A 1 73  ? 162.035 177.561 145.723 1.00 74.29  ? 73  ILE A N   1 
ATOM 549  C CA  . ILE A 1 73  ? 162.427 178.919 146.080 1.00 68.21  ? 73  ILE A CA  1 
ATOM 550  C C   . ILE A 1 73  ? 161.191 179.785 146.276 1.00 76.46  ? 73  ILE A C   1 
ATOM 551  O O   . ILE A 1 73  ? 161.104 180.573 147.228 1.00 83.29  ? 73  ILE A O   1 
ATOM 552  C CB  . ILE A 1 73  ? 163.365 179.503 145.009 1.00 67.68  ? 73  ILE A CB  1 
ATOM 553  C CG1 . ILE A 1 73  ? 164.754 178.873 145.128 1.00 70.76  ? 73  ILE A CG1 1 
ATOM 554  C CG2 . ILE A 1 73  ? 163.450 181.014 145.142 1.00 74.10  ? 73  ILE A CG2 1 
ATOM 555  C CD1 . ILE A 1 73  ? 165.632 179.089 143.915 1.00 73.71  ? 73  ILE A CD1 1 
ATOM 556  N N   . TYR A 1 74  ? 160.215 179.655 145.376 1.00 67.26  ? 74  TYR A N   1 
ATOM 557  C CA  . TYR A 1 74  ? 158.992 180.436 145.499 1.00 66.90  ? 74  TYR A CA  1 
ATOM 558  C C   . TYR A 1 74  ? 158.255 180.085 146.783 1.00 66.11  ? 74  TYR A C   1 
ATOM 559  O O   . TYR A 1 74  ? 157.743 180.969 147.478 1.00 76.55  ? 74  TYR A O   1 
ATOM 560  C CB  . TYR A 1 74  ? 158.098 180.213 144.277 1.00 64.30  ? 74  TYR A CB  1 
ATOM 561  C CG  . TYR A 1 74  ? 156.666 180.662 144.474 1.00 68.97  ? 74  TYR A CG  1 
ATOM 562  C CD1 . TYR A 1 74  ? 156.205 181.836 143.901 1.00 71.09  ? 74  TYR A CD1 1 
ATOM 563  C CD2 . TYR A 1 74  ? 155.766 179.896 145.203 1.00 76.08  ? 74  TYR A CD2 1 
ATOM 564  C CE1 . TYR A 1 74  ? 154.901 182.251 144.078 1.00 73.88  ? 74  TYR A CE1 1 
ATOM 565  C CE2 . TYR A 1 74  ? 154.466 180.306 145.387 1.00 74.45  ? 74  TYR A CE2 1 
ATOM 566  C CZ  . TYR A 1 74  ? 154.035 181.477 144.815 1.00 76.58  ? 74  TYR A CZ  1 
ATOM 567  O OH  . TYR A 1 74  ? 152.733 181.880 144.991 1.00 84.74  ? 74  TYR A OH  1 
ATOM 568  N N   . TYR A 1 75  ? 158.166 178.794 147.102 1.00 55.98  ? 75  TYR A N   1 
ATOM 569  C CA  . TYR A 1 75  ? 157.489 178.391 148.328 1.00 64.29  ? 75  TYR A CA  1 
ATOM 570  C C   . TYR A 1 75  ? 158.155 179.021 149.540 1.00 67.65  ? 75  TYR A C   1 
ATOM 571  O O   . TYR A 1 75  ? 157.483 179.576 150.415 1.00 73.59  ? 75  TYR A O   1 
ATOM 572  C CB  . TYR A 1 75  ? 157.483 176.866 148.462 1.00 69.90  ? 75  TYR A CB  1 
ATOM 573  C CG  . TYR A 1 75  ? 156.584 176.133 147.489 1.00 71.53  ? 75  TYR A CG  1 
ATOM 574  C CD1 . TYR A 1 75  ? 155.569 176.789 146.807 1.00 70.26  ? 75  TYR A CD1 1 
ATOM 575  C CD2 . TYR A 1 75  ? 156.746 174.775 147.264 1.00 66.65  ? 75  TYR A CD2 1 
ATOM 576  C CE1 . TYR A 1 75  ? 154.752 176.116 145.926 1.00 65.99  ? 75  TYR A CE1 1 
ATOM 577  C CE2 . TYR A 1 75  ? 155.933 174.095 146.387 1.00 63.00  ? 75  TYR A CE2 1 
ATOM 578  C CZ  . TYR A 1 75  ? 154.939 174.769 145.720 1.00 66.26  ? 75  TYR A CZ  1 
ATOM 579  O OH  . TYR A 1 75  ? 154.127 174.093 144.841 1.00 71.49  ? 75  TYR A OH  1 
ATOM 580  N N   . MET A 1 76  ? 159.486 178.951 149.605 1.00 76.03  ? 76  MET A N   1 
ATOM 581  C CA  . MET A 1 76  ? 160.191 179.532 150.743 1.00 77.40  ? 76  MET A CA  1 
ATOM 582  C C   . MET A 1 76  ? 159.927 181.030 150.840 1.00 76.94  ? 76  MET A C   1 
ATOM 583  O O   . MET A 1 76  ? 159.590 181.549 151.913 1.00 85.67  ? 76  MET A O   1 
ATOM 584  C CB  . MET A 1 76  ? 161.690 179.262 150.626 1.00 80.13  ? 76  MET A CB  1 
ATOM 585  C CG  . MET A 1 76  ? 162.118 177.911 151.174 1.00 88.01  ? 76  MET A CG  1 
ATOM 586  S SD  . MET A 1 76  ? 163.878 177.528 150.992 1.00 97.86  ? 76  MET A SD  1 
ATOM 587  C CE  . MET A 1 76  ? 164.521 178.986 150.169 1.00 85.06  ? 76  MET A CE  1 
ATOM 588  N N   . ILE A 1 77  ? 160.066 181.742 149.720 1.00 62.70  ? 77  ILE A N   1 
ATOM 589  C CA  . ILE A 1 77  ? 159.918 183.194 149.744 1.00 61.95  ? 77  ILE A CA  1 
ATOM 590  C C   . ILE A 1 77  ? 158.506 183.574 150.171 1.00 67.72  ? 77  ILE A C   1 
ATOM 591  O O   . ILE A 1 77  ? 158.309 184.452 151.020 1.00 73.69  ? 77  ILE A O   1 
ATOM 592  C CB  . ILE A 1 77  ? 160.269 183.792 148.371 1.00 61.73  ? 77  ILE A CB  1 
ATOM 593  C CG1 . ILE A 1 77  ? 161.756 183.606 148.073 1.00 64.91  ? 77  ILE A CG1 1 
ATOM 594  C CG2 . ILE A 1 77  ? 159.907 185.266 148.329 1.00 67.22  ? 77  ILE A CG2 1 
ATOM 595  C CD1 . ILE A 1 77  ? 162.104 183.743 146.608 1.00 66.29  ? 77  ILE A CD1 1 
ATOM 596  N N   . THR A 1 78  ? 157.499 182.917 149.591 1.00 69.00  ? 78  THR A N   1 
ATOM 597  C CA  . THR A 1 78  ? 156.121 183.274 149.897 1.00 62.81  ? 78  THR A CA  1 
ATOM 598  C C   . THR A 1 78  ? 155.740 182.893 151.319 1.00 64.46  ? 78  THR A C   1 
ATOM 599  O O   . THR A 1 78  ? 154.970 183.613 151.958 1.00 75.04  ? 78  THR A O   1 
ATOM 600  C CB  . THR A 1 78  ? 155.167 182.617 148.904 1.00 65.22  ? 78  THR A CB  1 
ATOM 601  O OG1 . THR A 1 78  ? 155.511 181.236 148.746 1.00 77.90  ? 78  THR A OG1 1 
ATOM 602  C CG2 . THR A 1 78  ? 155.240 183.318 147.560 1.00 64.84  ? 78  THR A CG2 1 
ATOM 603  N N   . THR A 1 79  ? 156.256 181.779 151.839 1.00 71.44  ? 79  THR A N   1 
ATOM 604  C CA  . THR A 1 79  ? 155.985 181.435 153.230 1.00 73.78  ? 79  THR A CA  1 
ATOM 605  C C   . THR A 1 79  ? 156.599 182.463 154.170 1.00 78.22  ? 79  THR A C   1 
ATOM 606  O O   . THR A 1 79  ? 155.977 182.872 155.158 1.00 82.73  ? 79  THR A O   1 
ATOM 607  C CB  . THR A 1 79  ? 156.514 180.035 153.540 1.00 73.49  ? 79  THR A CB  1 
ATOM 608  O OG1 . THR A 1 79  ? 155.925 179.090 152.638 1.00 75.73  ? 79  THR A OG1 1 
ATOM 609  C CG2 . THR A 1 79  ? 156.175 179.640 154.968 1.00 76.01  ? 79  THR A CG2 1 
ATOM 610  N N   . THR A 1 80  ? 157.827 182.898 153.876 1.00 74.92  ? 80  THR A N   1 
ATOM 611  C CA  . THR A 1 80  ? 158.446 183.939 154.690 1.00 71.65  ? 80  THR A CA  1 
ATOM 612  C C   . THR A 1 80  ? 157.625 185.221 154.642 1.00 75.16  ? 80  THR A C   1 
ATOM 613  O O   . THR A 1 80  ? 157.408 185.877 155.668 1.00 78.22  ? 80  THR A O   1 
ATOM 614  C CB  . THR A 1 80  ? 159.874 184.197 154.213 1.00 72.55  ? 80  THR A CB  1 
ATOM 615  O OG1 . THR A 1 80  ? 160.612 182.969 154.218 1.00 79.23  ? 80  THR A OG1 1 
ATOM 616  C CG2 . THR A 1 80  ? 160.564 185.205 155.117 1.00 77.65  ? 80  THR A CG2 1 
ATOM 617  N N   . LEU A 1 81  ? 157.156 185.590 153.449 1.00 72.93  ? 81  LEU A N   1 
ATOM 618  C CA  . LEU A 1 81  ? 156.317 186.777 153.323 1.00 65.68  ? 81  LEU A CA  1 
ATOM 619  C C   . LEU A 1 81  ? 155.024 186.622 154.113 1.00 65.77  ? 81  LEU A C   1 
ATOM 620  O O   . LEU A 1 81  ? 154.553 187.578 154.738 1.00 77.34  ? 81  LEU A O   1 
ATOM 621  C CB  . LEU A 1 81  ? 156.013 187.052 151.852 1.00 68.66  ? 81  LEU A CB  1 
ATOM 622  C CG  . LEU A 1 81  ? 156.903 188.088 151.166 1.00 67.57  ? 81  LEU A CG  1 
ATOM 623  C CD1 . LEU A 1 81  ? 158.372 187.764 151.363 1.00 68.72  ? 81  LEU A CD1 1 
ATOM 624  C CD2 . LEU A 1 81  ? 156.569 188.164 149.688 1.00 68.29  ? 81  LEU A CD2 1 
ATOM 625  N N   . ALA A 1 82  ? 154.431 185.429 154.088 1.00 64.33  ? 82  ALA A N   1 
ATOM 626  C CA  . ALA A 1 82  ? 153.197 185.200 154.829 1.00 66.93  ? 82  ALA A CA  1 
ATOM 627  C C   . ALA A 1 82  ? 153.420 185.356 156.325 1.00 73.18  ? 82  ALA A C   1 
ATOM 628  O O   . ALA A 1 82  ? 152.608 185.978 157.020 1.00 77.62  ? 82  ALA A O   1 
ATOM 629  C CB  . ALA A 1 82  ? 152.648 183.809 154.515 1.00 73.32  ? 82  ALA A CB  1 
ATOM 630  N N   . VAL A 1 83  ? 154.514 184.797 156.843 1.00 76.03  ? 83  VAL A N   1 
ATOM 631  C CA  . VAL A 1 83  ? 154.789 184.924 158.272 1.00 72.60  ? 83  VAL A CA  1 
ATOM 632  C C   . VAL A 1 83  ? 155.047 186.381 158.631 1.00 79.85  ? 83  VAL A C   1 
ATOM 633  O O   . VAL A 1 83  ? 154.601 186.869 159.676 1.00 84.37  ? 83  VAL A O   1 
ATOM 634  C CB  . VAL A 1 83  ? 155.968 184.031 158.697 1.00 76.52  ? 83  VAL A CB  1 
ATOM 635  C CG1 . VAL A 1 83  ? 155.954 183.856 160.204 1.00 79.06  ? 83  VAL A CG1 1 
ATOM 636  C CG2 . VAL A 1 83  ? 155.916 182.676 158.012 1.00 83.01  ? 83  VAL A CG2 1 
ATOM 637  N N   . THR A 1 84  ? 155.783 187.096 157.778 1.00 81.80  ? 84  THR A N   1 
ATOM 638  C CA  . THR A 1 84  ? 156.034 188.511 158.030 1.00 77.14  ? 84  THR A CA  1 
ATOM 639  C C   . THR A 1 84  ? 154.728 189.294 158.071 1.00 74.65  ? 84  THR A C   1 
ATOM 640  O O   . THR A 1 84  ? 154.522 190.139 158.951 1.00 75.71  ? 84  THR A O   1 
ATOM 641  C CB  . THR A 1 84  ? 156.965 189.073 156.955 1.00 81.92  ? 84  THR A CB  1 
ATOM 642  O OG1 . THR A 1 84  ? 158.310 188.655 157.217 1.00 80.79  ? 84  THR A OG1 1 
ATOM 643  C CG2 . THR A 1 84  ? 156.901 190.595 156.923 1.00 79.23  ? 84  THR A CG2 1 
ATOM 644  N N   . ILE A 1 85  ? 153.834 189.027 157.120 1.00 71.64  ? 85  ILE A N   1 
ATOM 645  C CA  . ILE A 1 85  ? 152.555 189.728 157.080 1.00 66.89  ? 85  ILE A CA  1 
ATOM 646  C C   . ILE A 1 85  ? 151.747 189.416 158.331 1.00 73.23  ? 85  ILE A C   1 
ATOM 647  O O   . ILE A 1 85  ? 151.126 190.302 158.929 1.00 79.42  ? 85  ILE A O   1 
ATOM 648  C CB  . ILE A 1 85  ? 151.784 189.359 155.801 1.00 64.74  ? 85  ILE A CB  1 
ATOM 649  C CG1 . ILE A 1 85  ? 152.419 190.044 154.591 1.00 69.37  ? 85  ILE A CG1 1 
ATOM 650  C CG2 . ILE A 1 85  ? 150.322 189.752 155.932 1.00 71.30  ? 85  ILE A CG2 1 
ATOM 651  C CD1 . ILE A 1 85  ? 151.998 189.459 153.265 1.00 73.43  ? 85  ILE A CD1 1 
ATOM 652  N N   . GLY A 1 86  ? 151.738 188.148 158.740 1.00 75.79  ? 86  GLY A N   1 
ATOM 653  C CA  . GLY A 1 86  ? 151.017 187.782 159.946 1.00 74.46  ? 86  GLY A CA  1 
ATOM 654  C C   . GLY A 1 86  ? 151.551 188.487 161.177 1.00 75.66  ? 86  GLY A C   1 
ATOM 655  O O   . GLY A 1 86  ? 150.782 188.992 161.997 1.00 73.67  ? 86  GLY A O   1 
ATOM 656  N N   . LEU A 1 87  ? 152.877 188.533 161.324 1.00 80.15  ? 87  LEU A N   1 
ATOM 657  C CA  . LEU A 1 87  ? 153.470 189.208 162.474 1.00 76.94  ? 87  LEU A CA  1 
ATOM 658  C C   . LEU A 1 87  ? 153.141 190.695 162.464 1.00 80.41  ? 87  LEU A C   1 
ATOM 659  O O   . LEU A 1 87  ? 152.762 191.266 163.494 1.00 86.23  ? 87  LEU A O   1 
ATOM 660  C CB  . LEU A 1 87  ? 154.983 188.999 162.484 1.00 81.77  ? 87  LEU A CB  1 
ATOM 661  C CG  . LEU A 1 87  ? 155.466 187.600 162.866 1.00 85.37  ? 87  LEU A CG  1 
ATOM 662  C CD1 . LEU A 1 87  ? 156.877 187.371 162.359 1.00 88.64  ? 87  LEU A CD1 1 
ATOM 663  C CD2 . LEU A 1 87  ? 155.396 187.399 164.365 1.00 82.74  ? 87  LEU A CD2 1 
ATOM 664  N N   . ILE A 1 88  ? 153.271 191.341 161.305 1.00 74.15  ? 88  ILE A N   1 
ATOM 665  C CA  . ILE A 1 88  ? 152.978 192.769 161.220 1.00 74.76  ? 88  ILE A CA  1 
ATOM 666  C C   . ILE A 1 88  ? 151.520 193.028 161.576 1.00 82.01  ? 88  ILE A C   1 
ATOM 667  O O   . ILE A 1 88  ? 151.200 193.962 162.320 1.00 82.57  ? 88  ILE A O   1 
ATOM 668  C CB  . ILE A 1 88  ? 153.330 193.307 159.821 1.00 70.94  ? 88  ILE A CB  1 
ATOM 669  C CG1 . ILE A 1 88  ? 154.785 193.780 159.774 1.00 78.97  ? 88  ILE A CG1 1 
ATOM 670  C CG2 . ILE A 1 88  ? 152.416 194.460 159.429 1.00 69.51  ? 88  ILE A CG2 1 
ATOM 671  C CD1 . ILE A 1 88  ? 155.805 192.762 160.231 1.00 76.08  ? 88  ILE A CD1 1 
ATOM 672  N N   . LEU A 1 89  ? 150.612 192.208 161.044 1.00 83.60  ? 89  LEU A N   1 
ATOM 673  C CA  . LEU A 1 89  ? 149.194 192.412 161.313 1.00 77.08  ? 89  LEU A CA  1 
ATOM 674  C C   . LEU A 1 89  ? 148.874 192.189 162.784 1.00 75.64  ? 89  LEU A C   1 
ATOM 675  O O   . LEU A 1 89  ? 148.115 192.959 163.383 1.00 78.35  ? 89  LEU A O   1 
ATOM 676  C CB  . LEU A 1 89  ? 148.361 191.478 160.439 1.00 75.82  ? 89  LEU A CB  1 
ATOM 677  C CG  . LEU A 1 89  ? 147.666 192.133 159.245 1.00 78.63  ? 89  LEU A CG  1 
ATOM 678  C CD1 . LEU A 1 89  ? 146.473 192.939 159.698 1.00 78.51  ? 89  LEU A CD1 1 
ATOM 679  C CD2 . LEU A 1 89  ? 148.627 193.000 158.446 1.00 78.39  ? 89  LEU A CD2 1 
ATOM 680  N N   . ALA A 1 90  ? 149.441 191.142 163.386 1.00 82.77  ? 90  ALA A N   1 
ATOM 681  C CA  . ALA A 1 90  ? 149.173 190.861 164.790 1.00 87.48  ? 90  ALA A CA  1 
ATOM 682  C C   . ALA A 1 90  ? 149.873 191.842 165.716 1.00 87.63  ? 90  ALA A C   1 
ATOM 683  O O   . ALA A 1 90  ? 149.578 191.860 166.915 1.00 86.36  ? 90  ALA A O   1 
ATOM 684  C CB  . ALA A 1 90  ? 149.599 189.435 165.132 1.00 83.84  ? 90  ALA A CB  1 
ATOM 685  N N   . ASN A 1 91  ? 150.814 192.631 165.199 1.00 82.57  ? 91  ASN A N   1 
ATOM 686  C CA  . ASN A 1 91  ? 151.395 193.713 165.983 1.00 82.18  ? 91  ASN A CA  1 
ATOM 687  C C   . ASN A 1 91  ? 150.575 194.994 165.867 1.00 86.26  ? 91  ASN A C   1 
ATOM 688  O O   . ASN A 1 91  ? 150.300 195.650 166.876 1.00 88.42  ? 91  ASN A O   1 
ATOM 689  C CB  . ASN A 1 91  ? 152.839 193.965 165.543 1.00 83.86  ? 91  ASN A CB  1 
ATOM 690  C CG  . ASN A 1 91  ? 153.817 193.007 166.188 1.00 83.31  ? 91  ASN A CG  1 
ATOM 691  O OD1 . ASN A 1 91  ? 154.227 193.200 167.330 1.00 83.40  ? 91  ASN A OD1 1 
ATOM 692  N ND2 . ASN A 1 91  ? 154.194 191.966 165.458 1.00 84.28  ? 91  ASN A ND2 1 
ATOM 693  N N   . ILE A 1 92  ? 150.176 195.362 164.648 1.00 85.07  ? 92  ILE A N   1 
ATOM 694  C CA  . ILE A 1 92  ? 149.357 196.561 164.464 1.00 87.37  ? 92  ILE A CA  1 
ATOM 695  C C   . ILE A 1 92  ? 148.021 196.392 165.176 1.00 85.78  ? 92  ILE A C   1 
ATOM 696  O O   . ILE A 1 92  ? 147.587 197.260 165.941 1.00 83.05  ? 92  ILE A O   1 
ATOM 697  C CB  . ILE A 1 92  ? 149.171 196.863 162.966 1.00 82.05  ? 92  ILE A CB  1 
ATOM 698  C CG1 . ILE A 1 92  ? 150.362 197.658 162.423 1.00 81.58  ? 92  ILE A CG1 1 
ATOM 699  C CG2 . ILE A 1 92  ? 147.890 197.649 162.728 1.00 81.99  ? 92  ILE A CG2 1 
ATOM 700  C CD1 . ILE A 1 92  ? 151.718 197.173 162.895 1.00 81.09  ? 92  ILE A CD1 1 
ATOM 701  N N   . PHE A 1 93  ? 147.347 195.273 164.929 1.00 93.23  ? 93  PHE A N   1 
ATOM 702  C CA  . PHE A 1 93  ? 146.234 194.865 165.770 1.00 87.81  ? 93  PHE A CA  1 
ATOM 703  C C   . PHE A 1 93  ? 146.774 194.110 166.976 1.00 88.53  ? 93  PHE A C   1 
ATOM 704  O O   . PHE A 1 93  ? 147.917 193.647 166.979 1.00 91.28  ? 93  PHE A O   1 
ATOM 705  C CB  . PHE A 1 93  ? 145.250 193.984 165.000 1.00 88.06  ? 93  PHE A CB  1 
ATOM 706  C CG  . PHE A 1 93  ? 144.593 194.674 163.839 1.00 87.69  ? 93  PHE A CG  1 
ATOM 707  C CD1 . PHE A 1 93  ? 145.323 195.025 162.718 1.00 86.77  ? 93  PHE A CD1 1 
ATOM 708  C CD2 . PHE A 1 93  ? 143.242 194.969 163.871 1.00 85.51  ? 93  PHE A CD2 1 
ATOM 709  C CE1 . PHE A 1 93  ? 144.719 195.659 161.653 1.00 83.40  ? 93  PHE A CE1 1 
ATOM 710  C CE2 . PHE A 1 93  ? 142.633 195.602 162.808 1.00 86.32  ? 93  PHE A CE2 1 
ATOM 711  C CZ  . PHE A 1 93  ? 143.373 195.947 161.698 1.00 86.45  ? 93  PHE A CZ  1 
ATOM 712  N N   . LYS A 1 94  ? 145.953 194.006 168.015 1.00 93.98  ? 94  LYS A N   1 
ATOM 713  C CA  . LYS A 1 94  ? 146.345 193.340 169.257 1.00 99.83  ? 94  LYS A CA  1 
ATOM 714  C C   . LYS A 1 94  ? 145.221 192.429 169.735 1.00 103.05 ? 94  LYS A C   1 
ATOM 715  O O   . LYS A 1 94  ? 144.585 192.683 170.763 1.00 106.80 ? 94  LYS A O   1 
ATOM 716  C CB  . LYS A 1 94  ? 146.719 194.376 170.315 1.00 96.16  ? 94  LYS A CB  1 
ATOM 717  C CG  . LYS A 1 94  ? 147.755 195.368 169.811 1.00 96.02  ? 94  LYS A CG  1 
ATOM 718  C CD  . LYS A 1 94  ? 148.419 196.141 170.932 1.00 100.21 ? 94  LYS A CD  1 
ATOM 719  C CE  . LYS A 1 94  ? 149.552 197.004 170.395 1.00 98.01  ? 94  LYS A CE  1 
ATOM 720  N NZ  . LYS A 1 94  ? 150.344 197.645 171.480 1.00 97.97  ? 94  LYS A NZ  1 
ATOM 721  N N   . PRO A 1 95  ? 144.949 191.346 169.003 1.00 90.06  ? 95  PRO A N   1 
ATOM 722  C CA  . PRO A 1 95  ? 143.857 190.450 169.416 1.00 87.61  ? 95  PRO A CA  1 
ATOM 723  C C   . PRO A 1 95  ? 144.068 189.834 170.786 1.00 88.13  ? 95  PRO A C   1 
ATOM 724  O O   . PRO A 1 95  ? 143.094 189.601 171.513 1.00 89.39  ? 95  PRO A O   1 
ATOM 725  C CB  . PRO A 1 95  ? 143.843 189.389 168.307 1.00 86.99  ? 95  PRO A CB  1 
ATOM 726  C CG  . PRO A 1 95  ? 145.220 189.411 167.742 1.00 83.48  ? 95  PRO A CG  1 
ATOM 727  C CD  . PRO A 1 95  ? 145.670 190.836 167.825 1.00 85.73  ? 95  PRO A CD  1 
ATOM 728  N N   . GLY A 1 96  ? 145.317 189.561 171.163 1.00 92.68  ? 96  GLY A N   1 
ATOM 729  C CA  . GLY A 1 96  ? 145.578 188.917 172.437 1.00 94.26  ? 96  GLY A CA  1 
ATOM 730  C C   . GLY A 1 96  ? 145.385 189.818 173.636 1.00 94.92  ? 96  GLY A C   1 
ATOM 731  O O   . GLY A 1 96  ? 145.181 189.317 174.746 1.00 96.47  ? 96  GLY A O   1 
ATOM 732  N N   . LYS A 1 97  ? 145.439 191.132 173.440 1.00 99.94  ? 97  LYS A N   1 
ATOM 733  C CA  . LYS A 1 97  ? 145.317 192.058 174.557 1.00 103.57 ? 97  LYS A CA  1 
ATOM 734  C C   . LYS A 1 97  ? 143.989 191.849 175.273 1.00 105.40 ? 97  LYS A C   1 
ATOM 735  O O   . LYS A 1 97  ? 142.931 191.776 174.641 1.00 103.28 ? 97  LYS A O   1 
ATOM 736  C CB  . LYS A 1 97  ? 145.440 193.497 174.050 1.00 104.44 ? 97  LYS A CB  1 
ATOM 737  C CG  . LYS A 1 97  ? 145.118 194.582 175.078 1.00 106.30 ? 97  LYS A CG  1 
ATOM 738  C CD  . LYS A 1 97  ? 144.849 195.923 174.409 1.00 104.47 ? 97  LYS A CD  1 
ATOM 739  C CE  . LYS A 1 97  ? 143.493 195.955 173.717 1.00 103.31 ? 97  LYS A CE  1 
ATOM 740  N NZ  . LYS A 1 97  ? 143.496 196.844 172.523 1.00 103.44 ? 97  LYS A NZ  1 
ATOM 741  N N   . GLY A 1 98  ? 144.050 191.751 176.601 1.00 107.60 ? 98  GLY A N   1 
ATOM 742  C CA  . GLY A 1 98  ? 142.873 191.622 177.427 1.00 106.54 ? 98  GLY A CA  1 
ATOM 743  C C   . GLY A 1 98  ? 142.474 190.201 177.764 1.00 106.20 ? 98  GLY A C   1 
ATOM 744  O O   . GLY A 1 98  ? 141.713 189.998 178.717 1.00 108.23 ? 98  GLY A O   1 
ATOM 745  N N   . LEU A 1 99  ? 142.961 189.214 177.021 1.00 109.64 ? 99  LEU A N   1 
ATOM 746  C CA  . LEU A 1 99  ? 142.595 187.826 177.255 1.00 113.00 ? 99  LEU A CA  1 
ATOM 747  C C   . LEU A 1 99  ? 143.632 187.136 178.135 1.00 112.97 ? 99  LEU A C   1 
ATOM 748  O O   . LEU A 1 99  ? 144.757 187.611 178.308 1.00 109.98 ? 99  LEU A O   1 
ATOM 749  C CB  . LEU A 1 99  ? 142.449 187.076 175.931 1.00 112.46 ? 99  LEU A CB  1 
ATOM 750  C CG  . LEU A 1 99  ? 141.121 187.285 175.200 1.00 110.14 ? 99  LEU A CG  1 
ATOM 751  C CD1 . LEU A 1 99  ? 141.073 188.656 174.546 1.00 110.37 ? 99  LEU A CD1 1 
ATOM 752  C CD2 . LEU A 1 99  ? 140.900 186.191 174.171 1.00 107.74 ? 99  LEU A CD2 1 
ATOM 753  N N   . SER A 1 100 ? 143.235 185.997 178.694 1.00 118.53 ? 100 SER A N   1 
ATOM 754  C CA  . SER A 1 100 ? 144.113 185.219 179.558 1.00 117.55 ? 100 SER A CA  1 
ATOM 755  C C   . SER A 1 100 ? 143.601 183.790 179.706 1.00 114.33 ? 100 SER A C   1 
ATOM 756  O O   . SER A 1 100 ? 142.807 183.496 180.599 1.00 111.56 ? 100 SER A O   1 
ATOM 757  C CB  . SER A 1 100 ? 144.234 185.878 180.932 1.00 114.06 ? 100 SER A CB  1 
ATOM 758  O OG  . SER A 1 100 ? 144.908 187.121 180.843 1.00 112.82 ? 100 SER A OG  1 
ATOM 759  N N   . PRO A 1 113 ? 160.734 165.270 165.760 1.00 105.84 ? 113 PRO A N   1 
ATOM 760  C CA  . PRO A 1 113 ? 162.032 164.637 165.502 1.00 109.44 ? 113 PRO A CA  1 
ATOM 761  C C   . PRO A 1 113 ? 163.050 165.602 164.905 1.00 108.07 ? 113 PRO A C   1 
ATOM 762  O O   . PRO A 1 113 ? 162.690 166.708 164.502 1.00 105.55 ? 113 PRO A O   1 
ATOM 763  C CB  . PRO A 1 113 ? 161.689 163.525 164.508 1.00 105.02 ? 113 PRO A CB  1 
ATOM 764  C CG  . PRO A 1 113 ? 160.261 163.209 164.768 1.00 106.27 ? 113 PRO A CG  1 
ATOM 765  C CD  . PRO A 1 113 ? 159.616 164.493 165.198 1.00 105.43 ? 113 PRO A CD  1 
ATOM 766  N N   . SER A 1 114 ? 164.311 165.181 164.852 1.00 105.11 ? 114 SER A N   1 
ATOM 767  C CA  . SER A 1 114 ? 165.346 166.013 164.257 1.00 103.77 ? 114 SER A CA  1 
ATOM 768  C C   . SER A 1 114 ? 165.051 166.240 162.780 1.00 100.72 ? 114 SER A C   1 
ATOM 769  O O   . SER A 1 114 ? 164.527 165.365 162.087 1.00 101.46 ? 114 SER A O   1 
ATOM 770  C CB  . SER A 1 114 ? 166.716 165.358 164.426 1.00 104.16 ? 114 SER A CB  1 
ATOM 771  O OG  . SER A 1 114 ? 167.729 166.136 163.812 1.00 101.69 ? 114 SER A OG  1 
ATOM 772  N N   . PHE A 1 115 ? 165.396 167.436 162.297 1.00 97.36  ? 115 PHE A N   1 
ATOM 773  C CA  . PHE A 1 115 ? 165.108 167.773 160.907 1.00 94.57  ? 115 PHE A CA  1 
ATOM 774  C C   . PHE A 1 115 ? 165.721 166.755 159.958 1.00 93.20  ? 115 PHE A C   1 
ATOM 775  O O   . PHE A 1 115 ? 165.064 166.301 159.016 1.00 99.27  ? 115 PHE A O   1 
ATOM 776  C CB  . PHE A 1 115 ? 165.616 169.181 160.580 1.00 99.49  ? 115 PHE A CB  1 
ATOM 777  C CG  . PHE A 1 115 ? 165.115 170.251 161.518 1.00 107.06 ? 115 PHE A CG  1 
ATOM 778  C CD1 . PHE A 1 115 ? 164.022 170.026 162.343 1.00 104.53 ? 115 PHE A CD1 1 
ATOM 779  C CD2 . PHE A 1 115 ? 165.738 171.487 161.566 1.00 100.26 ? 115 PHE A CD2 1 
ATOM 780  C CE1 . PHE A 1 115 ? 163.568 171.011 163.198 1.00 98.80  ? 115 PHE A CE1 1 
ATOM 781  C CE2 . PHE A 1 115 ? 165.286 172.474 162.420 1.00 98.61  ? 115 PHE A CE2 1 
ATOM 782  C CZ  . PHE A 1 115 ? 164.200 172.236 163.236 1.00 98.45  ? 115 PHE A CZ  1 
ATOM 783  N N   . THR A 1 116 ? 166.975 166.367 160.200 1.00 87.51  ? 116 THR A N   1 
ATOM 784  C CA  . THR A 1 116 ? 167.611 165.370 159.345 1.00 91.13  ? 116 THR A CA  1 
ATOM 785  C C   . THR A 1 116 ? 166.768 164.104 159.263 1.00 89.20  ? 116 THR A C   1 
ATOM 786  O O   . THR A 1 116 ? 166.724 163.443 158.220 1.00 88.90  ? 116 THR A O   1 
ATOM 787  C CB  . THR A 1 116 ? 169.012 165.044 159.863 1.00 89.97  ? 116 THR A CB  1 
ATOM 788  O OG1 . THR A 1 116 ? 169.681 164.190 158.928 1.00 89.53  ? 116 THR A OG1 1 
ATOM 789  C CG2 . THR A 1 116 ? 168.939 164.344 161.211 1.00 88.96  ? 116 THR A CG2 1 
ATOM 790  N N   . GLU A 1 117 ? 166.087 163.752 160.354 1.00 89.79  ? 117 GLU A N   1 
ATOM 791  C CA  . GLU A 1 117 ? 165.217 162.583 160.338 1.00 87.17  ? 117 GLU A CA  1 
ATOM 792  C C   . GLU A 1 117 ? 163.963 162.850 159.517 1.00 85.33  ? 117 GLU A C   1 
ATOM 793  O O   . GLU A 1 117 ? 163.447 161.935 158.868 1.00 89.78  ? 117 GLU A O   1 
ATOM 794  C CB  . GLU A 1 117 ? 164.910 162.177 161.790 1.00 91.50  ? 117 GLU A CB  1 
ATOM 795  C CG  . GLU A 1 117 ? 164.083 160.893 162.050 1.00 94.28  ? 117 GLU A CG  1 
ATOM 796  C CD  . GLU A 1 117 ? 162.656 160.883 161.513 1.00 98.03  ? 117 GLU A CD  1 
ATOM 797  O OE1 . GLU A 1 117 ? 161.982 159.844 161.681 1.00 95.21  ? 117 GLU A OE1 1 
ATOM 798  O OE2 . GLU A 1 117 ? 162.158 161.915 161.028 1.00 97.54  ? 117 GLU A OE2 1 
ATOM 799  N N   . THR A 1 118 ? 163.464 164.089 159.521 1.00 85.00  ? 118 THR A N   1 
ATOM 800  C CA  . THR A 1 118 ? 162.261 164.396 158.753 1.00 81.86  ? 118 THR A CA  1 
ATOM 801  C C   . THR A 1 118 ? 162.542 164.384 157.256 1.00 81.64  ? 118 THR A C   1 
ATOM 802  O O   . THR A 1 118 ? 161.681 163.990 156.463 1.00 83.61  ? 118 THR A O   1 
ATOM 803  C CB  . THR A 1 118 ? 161.690 165.749 159.173 1.00 87.49  ? 118 THR A CB  1 
ATOM 804  O OG1 . THR A 1 118 ? 162.526 166.803 158.680 1.00 94.32  ? 118 THR A OG1 1 
ATOM 805  C CG2 . THR A 1 118 ? 161.593 165.843 160.683 1.00 86.55  ? 118 THR A CG2 1 
ATOM 806  N N   . LEU A 1 119 ? 163.734 164.822 156.845 1.00 80.12  ? 119 LEU A N   1 
ATOM 807  C CA  . LEU A 1 119 ? 164.109 164.690 155.442 1.00 74.77  ? 119 LEU A CA  1 
ATOM 808  C C   . LEU A 1 119 ? 164.118 163.227 155.026 1.00 75.82  ? 119 LEU A C   1 
ATOM 809  O O   . LEU A 1 119 ? 163.668 162.883 153.928 1.00 79.25  ? 119 LEU A O   1 
ATOM 810  C CB  . LEU A 1 119 ? 165.473 165.335 155.191 1.00 80.26  ? 119 LEU A CB  1 
ATOM 811  C CG  . LEU A 1 119 ? 165.539 166.867 155.104 1.00 83.50  ? 119 LEU A CG  1 
ATOM 812  C CD1 . LEU A 1 119 ? 164.369 167.446 154.323 1.00 82.07  ? 119 LEU A CD1 1 
ATOM 813  C CD2 . LEU A 1 119 ? 165.589 167.482 156.489 1.00 83.43  ? 119 LEU A CD2 1 
ATOM 814  N N   . LEU A 1 120 ? 164.627 162.350 155.885 1.00 74.78  ? 120 LEU A N   1 
ATOM 815  C CA  . LEU A 1 120 ? 164.367 160.933 155.713 1.00 62.10  ? 120 LEU A CA  1 
ATOM 816  C C   . LEU A 1 120 ? 162.899 160.648 156.012 1.00 65.06  ? 120 LEU A C   1 
ATOM 817  O O   . LEU A 1 120 ? 162.189 161.465 156.603 1.00 78.95  ? 120 LEU A O   1 
ATOM 818  C CB  . LEU A 1 120 ? 165.265 160.098 156.624 1.00 63.80  ? 120 LEU A CB  1 
ATOM 819  C CG  . LEU A 1 120 ? 166.684 159.838 156.120 1.00 65.89  ? 120 LEU A CG  1 
ATOM 820  C CD1 . LEU A 1 120 ? 167.433 161.139 155.887 1.00 74.35  ? 120 LEU A CD1 1 
ATOM 821  C CD2 . LEU A 1 120 ? 167.430 158.955 157.101 1.00 72.53  ? 120 LEU A CD2 1 
ATOM 822  N N   . ASN A 1 121 ? 162.440 159.476 155.578 1.00 60.12  ? 121 ASN A N   1 
ATOM 823  C CA  . ASN A 1 121 ? 161.028 159.112 155.650 1.00 63.54  ? 121 ASN A CA  1 
ATOM 824  C C   . ASN A 1 121 ? 160.225 159.867 154.598 1.00 61.73  ? 121 ASN A C   1 
ATOM 825  O O   . ASN A 1 121 ? 159.031 159.609 154.424 1.00 70.35  ? 121 ASN A O   1 
ATOM 826  C CB  . ASN A 1 121 ? 160.446 159.373 157.043 1.00 60.81  ? 121 ASN A CB  1 
ATOM 827  C CG  . ASN A 1 121 ? 161.439 159.109 158.154 1.00 67.32  ? 121 ASN A CG  1 
ATOM 828  O OD1 . ASN A 1 121 ? 161.621 159.935 159.045 1.00 66.28  ? 121 ASN A OD1 1 
ATOM 829  N ND2 . ASN A 1 121 ? 162.087 157.952 158.107 1.00 70.95  ? 121 ASN A ND2 1 
ATOM 830  N N   . MET A 1 122 ? 160.863 160.808 153.898 1.00 51.73  ? 122 MET A N   1 
ATOM 831  C CA  . MET A 1 122 ? 160.299 161.293 152.646 1.00 49.89  ? 122 MET A CA  1 
ATOM 832  C C   . MET A 1 122 ? 160.627 160.338 151.512 1.00 54.15  ? 122 MET A C   1 
ATOM 833  O O   . MET A 1 122 ? 160.017 160.410 150.440 1.00 61.33  ? 122 MET A O   1 
ATOM 834  C CB  . MET A 1 122 ? 160.828 162.690 152.331 1.00 54.79  ? 122 MET A CB  1 
ATOM 835  C CG  . MET A 1 122 ? 160.056 163.807 153.008 1.00 63.29  ? 122 MET A CG  1 
ATOM 836  S SD  . MET A 1 122 ? 160.651 165.478 152.658 1.00 77.31  ? 122 MET A SD  1 
ATOM 837  C CE  . MET A 1 122 ? 161.924 165.197 151.429 1.00 59.92  ? 122 MET A CE  1 
ATOM 838  N N   . ILE A 1 123 ? 161.588 159.443 151.731 1.00 47.13  ? 123 ILE A N   1 
ATOM 839  C CA  . ILE A 1 123 ? 161.918 158.391 150.779 1.00 41.64  ? 123 ILE A CA  1 
ATOM 840  C C   . ILE A 1 123 ? 161.226 157.115 151.253 1.00 45.31  ? 123 ILE A C   1 
ATOM 841  O O   . ILE A 1 123 ? 161.631 156.558 152.286 1.00 55.66  ? 123 ILE A O   1 
ATOM 842  C CB  . ILE A 1 123 ? 163.435 158.182 150.677 1.00 42.76  ? 123 ILE A CB  1 
ATOM 843  C CG1 . ILE A 1 123 ? 164.152 159.510 150.427 1.00 44.81  ? 123 ILE A CG1 1 
ATOM 844  C CG2 . ILE A 1 123 ? 163.758 157.202 149.565 1.00 51.37  ? 123 ILE A CG2 1 
ATOM 845  C CD1 . ILE A 1 123 ? 165.642 159.441 150.656 1.00 44.48  ? 123 ILE A CD1 1 
ATOM 846  N N   . PRO A 1 124 ? 160.198 156.629 150.559 1.00 42.50  ? 124 PRO A N   1 
ATOM 847  C CA  . PRO A 1 124 ? 159.523 155.413 151.027 1.00 38.50  ? 124 PRO A CA  1 
ATOM 848  C C   . PRO A 1 124 ? 160.460 154.216 150.985 1.00 41.70  ? 124 PRO A C   1 
ATOM 849  O O   . PRO A 1 124 ? 161.186 154.012 150.010 1.00 52.20  ? 124 PRO A O   1 
ATOM 850  C CB  . PRO A 1 124 ? 158.354 155.249 150.049 1.00 44.99  ? 124 PRO A CB  1 
ATOM 851  C CG  . PRO A 1 124 ? 158.721 156.042 148.857 1.00 45.42  ? 124 PRO A CG  1 
ATOM 852  C CD  . PRO A 1 124 ? 159.597 157.155 149.322 1.00 47.80  ? 124 PRO A CD  1 
ATOM 853  N N   . THR A 1 125 ? 160.443 153.427 152.059 1.00 36.64  ? 125 THR A N   1 
ATOM 854  C CA  . THR A 1 125 ? 161.094 152.125 152.024 1.00 38.60  ? 125 THR A CA  1 
ATOM 855  C C   . THR A 1 125 ? 160.224 151.088 151.332 1.00 53.40  ? 125 THR A C   1 
ATOM 856  O O   . THR A 1 125 ? 160.703 149.989 151.034 1.00 59.65  ? 125 THR A O   1 
ATOM 857  C CB  . THR A 1 125 ? 161.426 151.658 153.440 1.00 43.82  ? 125 THR A CB  1 
ATOM 858  O OG1 . THR A 1 125 ? 160.233 151.641 154.232 1.00 50.89  ? 125 THR A OG1 1 
ATOM 859  C CG2 . THR A 1 125 ? 162.446 152.581 154.080 1.00 52.54  ? 125 THR A CG2 1 
ATOM 860  N N   . ASN A 1 126 ? 158.963 151.415 151.076 1.00 51.34  ? 126 ASN A N   1 
ATOM 861  C CA  . ASN A 1 126 ? 158.038 150.539 150.378 1.00 41.90  ? 126 ASN A CA  1 
ATOM 862  C C   . ASN A 1 126 ? 156.997 151.403 149.678 1.00 45.76  ? 126 ASN A C   1 
ATOM 863  O O   . ASN A 1 126 ? 156.146 152.000 150.347 1.00 52.68  ? 126 ASN A O   1 
ATOM 864  C CB  . ASN A 1 126 ? 157.376 149.569 151.355 1.00 38.66  ? 126 ASN A CB  1 
ATOM 865  C CG  . ASN A 1 126 ? 156.499 148.551 150.664 1.00 50.73  ? 126 ASN A CG  1 
ATOM 866  O OD1 . ASN A 1 126 ? 155.911 148.826 149.620 1.00 58.31  ? 126 ASN A OD1 1 
ATOM 867  N ND2 . ASN A 1 126 ? 156.406 147.364 151.244 1.00 58.87  ? 126 ASN A ND2 1 
ATOM 868  N N   . PRO A 1 127 ? 157.030 151.510 148.346 1.00 42.12  ? 127 PRO A N   1 
ATOM 869  C CA  . PRO A 1 127 ? 156.051 152.379 147.673 1.00 44.62  ? 127 PRO A CA  1 
ATOM 870  C C   . PRO A 1 127 ? 154.611 152.024 147.995 1.00 53.58  ? 127 PRO A C   1 
ATOM 871  O O   . PRO A 1 127 ? 153.773 152.919 148.160 1.00 57.87  ? 127 PRO A O   1 
ATOM 872  C CB  . PRO A 1 127 ? 156.369 152.171 146.187 1.00 44.31  ? 127 PRO A CB  1 
ATOM 873  C CG  . PRO A 1 127 ? 157.776 151.711 146.157 1.00 44.42  ? 127 PRO A CG  1 
ATOM 874  C CD  . PRO A 1 127 ? 157.975 150.905 147.394 1.00 40.22  ? 127 PRO A CD  1 
ATOM 875  N N   . PHE A 1 128 ? 154.300 150.732 148.099 1.00 47.61  ? 128 PHE A N   1 
ATOM 876  C CA  . PHE A 1 128 ? 152.931 150.330 148.391 1.00 39.18  ? 128 PHE A CA  1 
ATOM 877  C C   . PHE A 1 128 ? 152.556 150.629 149.835 1.00 46.08  ? 128 PHE A C   1 
ATOM 878  O O   . PHE A 1 128 ? 151.387 150.898 150.123 1.00 61.75  ? 128 PHE A O   1 
ATOM 879  C CB  . PHE A 1 128 ? 152.751 148.848 148.079 1.00 50.22  ? 128 PHE A CB  1 
ATOM 880  C CG  . PHE A 1 128 ? 153.254 148.459 146.722 1.00 51.09  ? 128 PHE A CG  1 
ATOM 881  C CD1 . PHE A 1 128 ? 152.541 148.792 145.585 1.00 54.54  ? 128 PHE A CD1 1 
ATOM 882  C CD2 . PHE A 1 128 ? 154.445 147.772 146.581 1.00 52.97  ? 128 PHE A CD2 1 
ATOM 883  C CE1 . PHE A 1 128 ? 153.003 148.440 144.334 1.00 52.72  ? 128 PHE A CE1 1 
ATOM 884  C CE2 . PHE A 1 128 ? 154.910 147.418 145.333 1.00 57.81  ? 128 PHE A CE2 1 
ATOM 885  C CZ  . PHE A 1 128 ? 154.189 147.753 144.208 1.00 55.05  ? 128 PHE A CZ  1 
ATOM 886  N N   . GLU A 1 129 ? 153.521 150.581 150.755 1.00 49.79  ? 129 GLU A N   1 
ATOM 887  C CA  . GLU A 1 129 ? 153.245 151.012 152.121 1.00 46.03  ? 129 GLU A CA  1 
ATOM 888  C C   . GLU A 1 129 ? 152.917 152.497 152.164 1.00 53.70  ? 129 GLU A C   1 
ATOM 889  O O   . GLU A 1 129 ? 152.013 152.922 152.891 1.00 58.54  ? 129 GLU A O   1 
ATOM 890  C CB  . GLU A 1 129 ? 154.438 150.709 153.023 1.00 50.16  ? 129 GLU A CB  1 
ATOM 891  C CG  . GLU A 1 129 ? 154.129 150.815 154.503 1.00 58.28  ? 129 GLU A CG  1 
ATOM 892  C CD  . GLU A 1 129 ? 155.379 150.873 155.357 1.00 66.76  ? 129 GLU A CD  1 
ATOM 893  O OE1 . GLU A 1 129 ? 156.491 150.861 154.791 1.00 68.89  ? 129 GLU A OE1 1 
ATOM 894  O OE2 . GLU A 1 129 ? 155.249 150.934 156.597 1.00 61.79  ? 129 GLU A OE2 1 
ATOM 895  N N   . ALA A 1 130 ? 153.650 153.304 151.397 1.00 50.04  ? 130 ALA A N   1 
ATOM 896  C CA  . ALA A 1 130 ? 153.339 154.725 151.315 1.00 37.45  ? 130 ALA A CA  1 
ATOM 897  C C   . ALA A 1 130 ? 151.956 154.941 150.720 1.00 47.54  ? 130 ALA A C   1 
ATOM 898  O O   . ALA A 1 130 ? 151.186 155.783 151.194 1.00 57.76  ? 130 ALA A O   1 
ATOM 899  C CB  . ALA A 1 130 ? 154.400 155.444 150.485 1.00 42.77  ? 130 ALA A CB  1 
ATOM 900  N N   . MET A 1 131 ? 151.623 154.185 149.674 1.00 56.85  ? 131 MET A N   1 
ATOM 901  C CA  . MET A 1 131 ? 150.313 154.327 149.048 1.00 47.44  ? 131 MET A CA  1 
ATOM 902  C C   . MET A 1 131 ? 149.199 153.963 150.022 1.00 43.29  ? 131 MET A C   1 
ATOM 903  O O   . MET A 1 131 ? 148.205 154.687 150.148 1.00 53.84  ? 131 MET A O   1 
ATOM 904  C CB  . MET A 1 131 ? 150.238 153.453 147.797 1.00 53.85  ? 131 MET A CB  1 
ATOM 905  C CG  . MET A 1 131 ? 149.749 154.180 146.559 1.00 62.33  ? 131 MET A CG  1 
ATOM 906  S SD  . MET A 1 131 ? 151.085 154.917 145.605 1.00 62.44  ? 131 MET A SD  1 
ATOM 907  C CE  . MET A 1 131 ? 151.844 153.454 144.907 1.00 58.14  ? 131 MET A CE  1 
ATOM 908  N N   . ALA A 1 132 ? 149.351 152.841 150.726 1.00 35.56  ? 132 ALA A N   1 
ATOM 909  C CA  . ALA A 1 132 ? 148.314 152.401 151.652 1.00 41.28  ? 132 ALA A CA  1 
ATOM 910  C C   . ALA A 1 132 ? 148.140 153.387 152.798 1.00 56.88  ? 132 ALA A C   1 
ATOM 911  O O   . ALA A 1 132 ? 147.011 153.705 153.188 1.00 65.86  ? 132 ALA A O   1 
ATOM 912  C CB  . ALA A 1 132 ? 148.652 151.012 152.190 1.00 48.00  ? 132 ALA A CB  1 
ATOM 913  N N   . GLU A 1 133 ? 149.246 153.880 153.355 1.00 62.29  ? 133 GLU A N   1 
ATOM 914  C CA  . GLU A 1 133 ? 149.170 154.828 154.457 1.00 57.59  ? 133 GLU A CA  1 
ATOM 915  C C   . GLU A 1 133 ? 148.823 156.235 153.998 1.00 53.51  ? 133 GLU A C   1 
ATOM 916  O O   . GLU A 1 133 ? 148.606 157.107 154.845 1.00 58.78  ? 133 GLU A O   1 
ATOM 917  C CB  . GLU A 1 133 ? 150.495 154.851 155.218 1.00 62.65  ? 133 GLU A CB  1 
ATOM 918  C CG  . GLU A 1 133 ? 150.871 153.519 155.836 1.00 63.87  ? 133 GLU A CG  1 
ATOM 919  C CD  . GLU A 1 133 ? 152.069 153.624 156.756 1.00 70.06  ? 133 GLU A CD  1 
ATOM 920  O OE1 . GLU A 1 133 ? 152.795 154.637 156.675 1.00 66.07  ? 133 GLU A OE1 1 
ATOM 921  O OE2 . GLU A 1 133 ? 152.286 152.693 157.559 1.00 69.39  ? 133 GLU A OE2 1 
ATOM 922  N N   . GLY A 1 134 ? 148.768 156.479 152.694 1.00 47.29  ? 134 GLY A N   1 
ATOM 923  C CA  . GLY A 1 134 ? 148.489 157.820 152.210 1.00 47.82  ? 134 GLY A CA  1 
ATOM 924  C C   . GLY A 1 134 ? 149.570 158.812 152.574 1.00 51.10  ? 134 GLY A C   1 
ATOM 925  O O   . GLY A 1 134 ? 149.269 159.973 152.875 1.00 61.78  ? 134 GLY A O   1 
ATOM 926  N N   . ASN A 1 135 ? 150.827 158.378 152.556 1.00 45.66  ? 135 ASN A N   1 
ATOM 927  C CA  . ASN A 1 135 ? 151.959 159.252 152.853 1.00 49.40  ? 135 ASN A CA  1 
ATOM 928  C C   . ASN A 1 135 ? 152.243 160.088 151.613 1.00 53.39  ? 135 ASN A C   1 
ATOM 929  O O   . ASN A 1 135 ? 152.852 159.614 150.652 1.00 56.28  ? 135 ASN A O   1 
ATOM 930  C CB  . ASN A 1 135 ? 153.173 158.432 153.268 1.00 45.76  ? 135 ASN A CB  1 
ATOM 931  C CG  . ASN A 1 135 ? 153.927 159.055 154.420 1.00 55.65  ? 135 ASN A CG  1 
ATOM 932  O OD1 . ASN A 1 135 ? 154.403 160.186 154.326 1.00 55.28  ? 135 ASN A OD1 1 
ATOM 933  N ND2 . ASN A 1 135 ? 154.037 158.322 155.520 1.00 57.53  ? 135 ASN A ND2 1 
ATOM 934  N N   . MET A 1 136 ? 151.795 161.344 151.630 1.00 48.50  ? 136 MET A N   1 
ATOM 935  C CA  . MET A 1 136 ? 151.823 162.152 150.417 1.00 44.87  ? 136 MET A CA  1 
ATOM 936  C C   . MET A 1 136 ? 153.247 162.456 149.973 1.00 45.72  ? 136 MET A C   1 
ATOM 937  O O   . MET A 1 136 ? 153.549 162.399 148.778 1.00 47.90  ? 136 MET A O   1 
ATOM 938  C CB  . MET A 1 136 ? 151.044 163.446 150.638 1.00 54.87  ? 136 MET A CB  1 
ATOM 939  C CG  . MET A 1 136 ? 149.543 163.326 150.407 1.00 61.81  ? 136 MET A CG  1 
ATOM 940  S SD  . MET A 1 136 ? 149.095 162.570 148.831 1.00 61.40  ? 136 MET A SD  1 
ATOM 941  C CE  . MET A 1 136 ? 147.647 161.634 149.307 1.00 52.03  ? 136 MET A CE  1 
ATOM 942  N N   . LEU A 1 137 ? 154.134 162.798 150.907 1.00 54.91  ? 137 LEU A N   1 
ATOM 943  C CA  . LEU A 1 137 ? 155.502 163.134 150.523 1.00 52.08  ? 137 LEU A CA  1 
ATOM 944  C C   . LEU A 1 137 ? 156.215 161.929 149.923 1.00 51.68  ? 137 LEU A C   1 
ATOM 945  O O   . LEU A 1 137 ? 156.924 162.047 148.917 1.00 58.85  ? 137 LEU A O   1 
ATOM 946  C CB  . LEU A 1 137 ? 156.272 163.668 151.730 1.00 50.15  ? 137 LEU A CB  1 
ATOM 947  C CG  . LEU A 1 137 ? 156.035 165.137 152.080 1.00 56.38  ? 137 LEU A CG  1 
ATOM 948  C CD1 . LEU A 1 137 ? 156.753 165.499 153.366 1.00 62.09  ? 137 LEU A CD1 1 
ATOM 949  C CD2 . LEU A 1 137 ? 156.488 166.043 150.948 1.00 51.78  ? 137 LEU A CD2 1 
ATOM 950  N N   . GLN A 1 138 ? 156.044 160.758 150.533 1.00 46.21  ? 138 GLN A N   1 
ATOM 951  C CA  . GLN A 1 138 ? 156.669 159.553 150.002 1.00 40.03  ? 138 GLN A CA  1 
ATOM 952  C C   . GLN A 1 138 ? 156.098 159.201 148.635 1.00 42.46  ? 138 GLN A C   1 
ATOM 953  O O   . GLN A 1 138 ? 156.832 158.805 147.722 1.00 56.83  ? 138 GLN A O   1 
ATOM 954  C CB  . GLN A 1 138 ? 156.478 158.400 150.983 1.00 39.59  ? 138 GLN A CB  1 
ATOM 955  C CG  . GLN A 1 138 ? 157.274 158.550 152.264 1.00 44.51  ? 138 GLN A CG  1 
ATOM 956  C CD  . GLN A 1 138 ? 156.914 157.507 153.295 1.00 51.55  ? 138 GLN A CD  1 
ATOM 957  O OE1 . GLN A 1 138 ? 156.000 156.710 153.094 1.00 59.23  ? 138 GLN A OE1 1 
ATOM 958  N NE2 . GLN A 1 138 ? 157.633 157.504 154.408 1.00 59.12  ? 138 GLN A NE2 1 
ATOM 959  N N   . ILE A 1 139 ? 154.781 159.337 148.477 1.00 36.34  ? 139 ILE A N   1 
ATOM 960  C CA  . ILE A 1 139 ? 154.164 159.080 147.181 1.00 37.63  ? 139 ILE A CA  1 
ATOM 961  C C   . ILE A 1 139 ? 154.723 160.031 146.135 1.00 39.86  ? 139 ILE A C   1 
ATOM 962  O O   . ILE A 1 139 ? 154.984 159.636 144.996 1.00 45.97  ? 139 ILE A O   1 
ATOM 963  C CB  . ILE A 1 139 ? 152.632 159.191 147.280 1.00 39.39  ? 139 ILE A CB  1 
ATOM 964  C CG1 . ILE A 1 139 ? 152.066 158.042 148.111 1.00 44.40  ? 139 ILE A CG1 1 
ATOM 965  C CG2 . ILE A 1 139 ? 152.009 159.191 145.896 1.00 39.52  ? 139 ILE A CG2 1 
ATOM 966  C CD1 . ILE A 1 139 ? 150.724 158.346 148.723 1.00 52.50  ? 139 ILE A CD1 1 
ATOM 967  N N   . ILE A 1 140 ? 154.913 161.299 146.500 1.00 44.46  ? 140 ILE A N   1 
ATOM 968  C CA  . ILE A 1 140 ? 155.429 162.279 145.548 1.00 40.46  ? 140 ILE A CA  1 
ATOM 969  C C   . ILE A 1 140 ? 156.866 161.947 145.171 1.00 43.64  ? 140 ILE A C   1 
ATOM 970  O O   . ILE A 1 140 ? 157.264 162.069 144.008 1.00 58.00  ? 140 ILE A O   1 
ATOM 971  C CB  . ILE A 1 140 ? 155.311 163.701 146.123 1.00 50.60  ? 140 ILE A CB  1 
ATOM 972  C CG1 . ILE A 1 140 ? 153.841 164.106 146.233 1.00 47.69  ? 140 ILE A CG1 1 
ATOM 973  C CG2 . ILE A 1 140 ? 156.063 164.688 145.250 1.00 48.79  ? 140 ILE A CG2 1 
ATOM 974  C CD1 . ILE A 1 140 ? 153.580 165.168 147.269 1.00 54.82  ? 140 ILE A CD1 1 
ATOM 975  N N   . VAL A 1 141 ? 157.672 161.533 146.148 1.00 34.30  ? 141 VAL A N   1 
ATOM 976  C CA  . VAL A 1 141 ? 159.058 161.174 145.854 1.00 36.27  ? 141 VAL A CA  1 
ATOM 977  C C   . VAL A 1 141 ? 159.102 159.988 144.899 1.00 39.83  ? 141 VAL A C   1 
ATOM 978  O O   . VAL A 1 141 ? 159.837 159.990 143.901 1.00 51.28  ? 141 VAL A O   1 
ATOM 979  C CB  . VAL A 1 141 ? 159.821 160.875 147.156 1.00 35.44  ? 141 VAL A CB  1 
ATOM 980  C CG1 . VAL A 1 141 ? 161.129 160.157 146.855 1.00 31.90  ? 141 VAL A CG1 1 
ATOM 981  C CG2 . VAL A 1 141 ? 160.066 162.159 147.932 1.00 40.95  ? 141 VAL A CG2 1 
ATOM 982  N N   . PHE A 1 142 ? 158.311 158.953 145.189 1.00 31.30  ? 142 PHE A N   1 
ATOM 983  C CA  . PHE A 1 142 ? 158.308 157.783 144.322 1.00 29.39  ? 142 PHE A CA  1 
ATOM 984  C C   . PHE A 1 142 ? 157.774 158.128 142.941 1.00 31.33  ? 142 PHE A C   1 
ATOM 985  O O   . PHE A 1 142 ? 158.261 157.607 141.934 1.00 42.76  ? 142 PHE A O   1 
ATOM 986  C CB  . PHE A 1 142 ? 157.486 156.657 144.939 1.00 28.06  ? 142 PHE A CB  1 
ATOM 987  C CG  . PHE A 1 142 ? 157.559 155.374 144.166 1.00 35.85  ? 142 PHE A CG  1 
ATOM 988  C CD1 . PHE A 1 142 ? 158.754 154.688 144.054 1.00 33.92  ? 142 PHE A CD1 1 
ATOM 989  C CD2 . PHE A 1 142 ? 156.439 154.862 143.539 1.00 39.02  ? 142 PHE A CD2 1 
ATOM 990  C CE1 . PHE A 1 142 ? 158.828 153.512 143.340 1.00 32.01  ? 142 PHE A CE1 1 
ATOM 991  C CE2 . PHE A 1 142 ? 156.509 153.686 142.823 1.00 33.07  ? 142 PHE A CE2 1 
ATOM 992  C CZ  . PHE A 1 142 ? 157.705 153.011 142.724 1.00 36.57  ? 142 PHE A CZ  1 
ATOM 993  N N   . ALA A 1 143 ? 156.766 158.997 142.872 1.00 40.30  ? 143 ALA A N   1 
ATOM 994  C CA  . ALA A 1 143 ? 156.227 159.405 141.583 1.00 38.39  ? 143 ALA A CA  1 
ATOM 995  C C   . ALA A 1 143 ? 157.259 160.181 140.780 1.00 40.03  ? 143 ALA A C   1 
ATOM 996  O O   . ALA A 1 143 ? 157.342 160.032 139.560 1.00 48.20  ? 143 ALA A O   1 
ATOM 997  C CB  . ALA A 1 143 ? 154.966 160.241 141.785 1.00 40.82  ? 143 ALA A CB  1 
ATOM 998  N N   . ILE A 1 144 ? 158.047 161.026 141.445 1.00 45.16  ? 144 ILE A N   1 
ATOM 999  C CA  . ILE A 1 144 ? 159.104 161.753 140.748 1.00 35.66  ? 144 ILE A CA  1 
ATOM 1000 C C   . ILE A 1 144 ? 160.128 160.777 140.188 1.00 41.46  ? 144 ILE A C   1 
ATOM 1001 O O   . ILE A 1 144 ? 160.553 160.889 139.032 1.00 48.57  ? 144 ILE A O   1 
ATOM 1002 C CB  . ILE A 1 144 ? 159.759 162.782 141.686 1.00 31.22  ? 144 ILE A CB  1 
ATOM 1003 C CG1 . ILE A 1 144 ? 158.801 163.943 141.945 1.00 42.22  ? 144 ILE A CG1 1 
ATOM 1004 C CG2 . ILE A 1 144 ? 161.053 163.297 141.086 1.00 36.86  ? 144 ILE A CG2 1 
ATOM 1005 C CD1 . ILE A 1 144 ? 159.100 164.708 143.208 1.00 53.38  ? 144 ILE A CD1 1 
ATOM 1006 N N   . PHE A 1 145 ? 160.538 159.800 140.998 1.00 39.21  ? 145 PHE A N   1 
ATOM 1007 C CA  . PHE A 1 145 ? 161.484 158.802 140.506 1.00 31.91  ? 145 PHE A CA  1 
ATOM 1008 C C   . PHE A 1 145 ? 160.905 158.032 139.324 1.00 38.41  ? 145 PHE A C   1 
ATOM 1009 O O   . PHE A 1 145 ? 161.588 157.815 138.314 1.00 44.33  ? 145 PHE A O   1 
ATOM 1010 C CB  . PHE A 1 145 ? 161.866 157.842 141.629 1.00 35.96  ? 145 PHE A CB  1 
ATOM 1011 C CG  . PHE A 1 145 ? 163.126 158.221 142.342 1.00 36.05  ? 145 PHE A CG  1 
ATOM 1012 C CD1 . PHE A 1 145 ? 164.360 157.942 141.785 1.00 34.22  ? 145 PHE A CD1 1 
ATOM 1013 C CD2 . PHE A 1 145 ? 163.078 158.858 143.568 1.00 37.88  ? 145 PHE A CD2 1 
ATOM 1014 C CE1 . PHE A 1 145 ? 165.522 158.290 142.438 1.00 39.35  ? 145 PHE A CE1 1 
ATOM 1015 C CE2 . PHE A 1 145 ? 164.237 159.209 144.224 1.00 41.82  ? 145 PHE A CE2 1 
ATOM 1016 C CZ  . PHE A 1 145 ? 165.461 158.924 143.659 1.00 45.55  ? 145 PHE A CZ  1 
ATOM 1017 N N   . PHE A 1 146 ? 159.643 157.618 139.431 1.00 39.02  ? 146 PHE A N   1 
ATOM 1018 C CA  . PHE A 1 146 ? 159.002 156.860 138.364 1.00 38.60  ? 146 PHE A CA  1 
ATOM 1019 C C   . PHE A 1 146 ? 158.905 157.681 137.086 1.00 40.87  ? 146 PHE A C   1 
ATOM 1020 O O   . PHE A 1 146 ? 159.186 157.180 135.991 1.00 55.41  ? 146 PHE A O   1 
ATOM 1021 C CB  . PHE A 1 146 ? 157.617 156.415 138.826 1.00 37.58  ? 146 PHE A CB  1 
ATOM 1022 C CG  . PHE A 1 146 ? 157.094 155.209 138.113 1.00 39.11  ? 146 PHE A CG  1 
ATOM 1023 C CD1 . PHE A 1 146 ? 157.491 153.942 138.490 1.00 44.06  ? 146 PHE A CD1 1 
ATOM 1024 C CD2 . PHE A 1 146 ? 156.189 155.342 137.079 1.00 37.70  ? 146 PHE A CD2 1 
ATOM 1025 C CE1 . PHE A 1 146 ? 157.007 152.831 137.838 1.00 44.32  ? 146 PHE A CE1 1 
ATOM 1026 C CE2 . PHE A 1 146 ? 155.701 154.234 136.426 1.00 40.56  ? 146 PHE A CE2 1 
ATOM 1027 C CZ  . PHE A 1 146 ? 156.109 152.977 136.806 1.00 41.40  ? 146 PHE A CZ  1 
ATOM 1028 N N   . GLY A 1 147 ? 158.507 158.947 137.204 1.00 29.17  ? 147 GLY A N   1 
ATOM 1029 C CA  . GLY A 1 147 ? 158.399 159.791 136.031 1.00 35.45  ? 147 GLY A CA  1 
ATOM 1030 C C   . GLY A 1 147 ? 159.741 160.052 135.381 1.00 37.07  ? 147 GLY A C   1 
ATOM 1031 O O   . GLY A 1 147 ? 159.848 160.074 134.154 1.00 46.32  ? 147 GLY A O   1 
ATOM 1032 N N   . ILE A 1 148 ? 160.781 160.260 136.188 1.00 37.86  ? 148 ILE A N   1 
ATOM 1033 C CA  . ILE A 1 148 ? 162.114 160.449 135.625 1.00 35.85  ? 148 ILE A CA  1 
ATOM 1034 C C   . ILE A 1 148 ? 162.549 159.194 134.883 1.00 39.27  ? 148 ILE A C   1 
ATOM 1035 O O   . ILE A 1 148 ? 163.096 159.265 133.775 1.00 54.32  ? 148 ILE A O   1 
ATOM 1036 C CB  . ILE A 1 148 ? 163.110 160.833 136.732 1.00 41.30  ? 148 ILE A CB  1 
ATOM 1037 C CG1 . ILE A 1 148 ? 162.886 162.283 137.155 1.00 40.18  ? 148 ILE A CG1 1 
ATOM 1038 C CG2 . ILE A 1 148 ? 164.536 160.644 136.251 1.00 33.43  ? 148 ILE A CG2 1 
ATOM 1039 C CD1 . ILE A 1 148 ? 163.495 162.628 138.489 1.00 39.37  ? 148 ILE A CD1 1 
ATOM 1040 N N   . ALA A 1 149 ? 162.303 158.024 135.474 1.00 37.03  ? 149 ALA A N   1 
ATOM 1041 C CA  . ALA A 1 149 ? 162.635 156.778 134.795 1.00 36.63  ? 149 ALA A CA  1 
ATOM 1042 C C   . ALA A 1 149 ? 161.902 156.675 133.464 1.00 43.06  ? 149 ALA A C   1 
ATOM 1043 O O   . ALA A 1 149 ? 162.495 156.322 132.441 1.00 43.90  ? 149 ALA A O   1 
ATOM 1044 C CB  . ALA A 1 149 ? 162.294 155.590 135.692 1.00 40.02  ? 149 ALA A CB  1 
ATOM 1045 N N   . LEU A 1 150 ? 160.609 156.997 133.456 1.00 54.69  ? 150 LEU A N   1 
ATOM 1046 C CA  . LEU A 1 150 ? 159.841 156.926 132.217 1.00 48.82  ? 150 LEU A CA  1 
ATOM 1047 C C   . LEU A 1 150 ? 160.374 157.906 131.180 1.00 55.08  ? 150 LEU A C   1 
ATOM 1048 O O   . LEU A 1 150 ? 160.421 157.594 129.985 1.00 60.28  ? 150 LEU A O   1 
ATOM 1049 C CB  . LEU A 1 150 ? 158.366 157.199 132.500 1.00 35.93  ? 150 LEU A CB  1 
ATOM 1050 C CG  . LEU A 1 150 ? 157.498 155.957 132.667 1.00 40.27  ? 150 LEU A CG  1 
ATOM 1051 C CD1 . LEU A 1 150 ? 158.117 155.005 133.669 1.00 54.22  ? 150 LEU A CD1 1 
ATOM 1052 C CD2 . LEU A 1 150 ? 156.105 156.356 133.102 1.00 42.40  ? 150 LEU A CD2 1 
ATOM 1053 N N   . ALA A 1 151 ? 160.770 159.101 131.616 1.00 40.77  ? 151 ALA A N   1 
ATOM 1054 C CA  . ALA A 1 151 ? 161.283 160.097 130.684 1.00 41.39  ? 151 ALA A CA  1 
ATOM 1055 C C   . ALA A 1 151 ? 162.614 159.663 130.086 1.00 40.77  ? 151 ALA A C   1 
ATOM 1056 O O   . ALA A 1 151 ? 162.905 159.958 128.921 1.00 48.25  ? 151 ALA A O   1 
ATOM 1057 C CB  . ALA A 1 151 ? 161.428 161.446 131.386 1.00 37.25  ? 151 ALA A CB  1 
ATOM 1058 N N   . LEU A 1 152 ? 163.441 158.967 130.865 1.00 41.67  ? 152 LEU A N   1 
ATOM 1059 C CA  . LEU A 1 152 ? 164.768 158.593 130.390 1.00 44.71  ? 152 LEU A CA  1 
ATOM 1060 C C   . LEU A 1 152 ? 164.776 157.354 129.501 1.00 54.08  ? 152 LEU A C   1 
ATOM 1061 O O   . LEU A 1 152 ? 165.788 157.107 128.837 1.00 57.67  ? 152 LEU A O   1 
ATOM 1062 C CB  . LEU A 1 152 ? 165.705 158.370 131.577 1.00 48.17  ? 152 LEU A CB  1 
ATOM 1063 C CG  . LEU A 1 152 ? 165.927 159.589 132.472 1.00 51.76  ? 152 LEU A CG  1 
ATOM 1064 C CD1 . LEU A 1 152 ? 166.656 159.197 133.743 1.00 53.42  ? 152 LEU A CD1 1 
ATOM 1065 C CD2 . LEU A 1 152 ? 166.697 160.660 131.724 1.00 49.49  ? 152 LEU A CD2 1 
ATOM 1066 N N   . MET A 1 153 ? 163.696 156.573 129.461 1.00 63.34  ? 153 MET A N   1 
ATOM 1067 C CA  . MET A 1 153 ? 163.654 155.369 128.637 1.00 68.08  ? 153 MET A CA  1 
ATOM 1068 C C   . MET A 1 153 ? 162.868 155.543 127.345 1.00 70.66  ? 153 MET A C   1 
ATOM 1069 O O   . MET A 1 153 ? 163.206 154.908 126.342 1.00 63.77  ? 153 MET A O   1 
ATOM 1070 C CB  . MET A 1 153 ? 163.067 154.192 129.429 1.00 61.03  ? 153 MET A CB  1 
ATOM 1071 C CG  . MET A 1 153 ? 163.637 154.038 130.834 1.00 66.25  ? 153 MET A CG  1 
ATOM 1072 S SD  . MET A 1 153 ? 162.672 153.019 131.971 1.00 91.69  ? 153 MET A SD  1 
ATOM 1073 C CE  . MET A 1 153 ? 161.552 152.165 130.869 1.00 65.13  ? 153 MET A CE  1 
ATOM 1074 N N   . GLY A 1 154 ? 161.839 156.376 127.340 1.00 79.38  ? 154 GLY A N   1 
ATOM 1075 C CA  . GLY A 1 154 ? 161.146 156.671 126.098 1.00 78.38  ? 154 GLY A CA  1 
ATOM 1076 C C   . GLY A 1 154 ? 160.382 155.471 125.570 1.00 81.43  ? 154 GLY A C   1 
ATOM 1077 O O   . GLY A 1 154 ? 159.404 155.012 126.172 1.00 82.29  ? 154 GLY A O   1 
ATOM 1078 N N   . GLU A 1 155 ? 160.831 154.950 124.425 1.00 81.86  ? 155 GLU A N   1 
ATOM 1079 C CA  . GLU A 1 155 ? 160.071 153.923 123.718 1.00 81.67  ? 155 GLU A CA  1 
ATOM 1080 C C   . GLU A 1 155 ? 159.846 152.685 124.575 1.00 78.37  ? 155 GLU A C   1 
ATOM 1081 O O   . GLU A 1 155 ? 158.826 152.004 124.425 1.00 73.97  ? 155 GLU A O   1 
ATOM 1082 C CB  . GLU A 1 155 ? 160.795 153.547 122.424 1.00 83.52  ? 155 GLU A CB  1 
ATOM 1083 C CG  . GLU A 1 155 ? 160.349 152.232 121.799 1.00 82.56  ? 155 GLU A CG  1 
ATOM 1084 C CD  . GLU A 1 155 ? 158.865 152.200 121.500 1.00 84.56  ? 155 GLU A CD  1 
ATOM 1085 O OE1 . GLU A 1 155 ? 158.256 153.285 121.392 1.00 83.75  ? 155 GLU A OE1 1 
ATOM 1086 O OE2 . GLU A 1 155 ? 158.307 151.091 121.374 1.00 85.26  ? 155 GLU A OE2 1 
ATOM 1087 N N   . LYS A 1 156 ? 160.782 152.370 125.468 1.00 70.92  ? 156 LYS A N   1 
ATOM 1088 C CA  . LYS A 1 156 ? 160.662 151.156 126.264 1.00 68.95  ? 156 LYS A CA  1 
ATOM 1089 C C   . LYS A 1 156 ? 159.556 151.253 127.307 1.00 65.12  ? 156 LYS A C   1 
ATOM 1090 O O   . LYS A 1 156 ? 159.159 150.226 127.865 1.00 66.13  ? 156 LYS A O   1 
ATOM 1091 C CB  . LYS A 1 156 ? 161.995 150.855 126.948 1.00 75.12  ? 156 LYS A CB  1 
ATOM 1092 C CG  . LYS A 1 156 ? 162.263 149.381 127.170 1.00 68.16  ? 156 LYS A CG  1 
ATOM 1093 C CD  . LYS A 1 156 ? 162.631 148.690 125.868 1.00 67.88  ? 156 LYS A CD  1 
ATOM 1094 C CE  . LYS A 1 156 ? 163.412 147.413 126.118 1.00 72.42  ? 156 LYS A CE  1 
ATOM 1095 N NZ  . LYS A 1 156 ? 164.810 147.693 126.547 1.00 73.18  ? 156 LYS A NZ  1 
ATOM 1096 N N   . ALA A 1 157 ? 159.050 152.456 127.577 1.00 55.27  ? 157 ALA A N   1 
ATOM 1097 C CA  . ALA A 1 157 ? 158.058 152.680 128.621 1.00 53.88  ? 157 ALA A CA  1 
ATOM 1098 C C   . ALA A 1 157 ? 156.658 152.904 128.068 1.00 59.35  ? 157 ALA A C   1 
ATOM 1099 O O   . ALA A 1 157 ? 155.773 153.334 128.814 1.00 70.81  ? 157 ALA A O   1 
ATOM 1100 C CB  . ALA A 1 157 ? 158.460 153.880 129.476 1.00 61.20  ? 157 ALA A CB  1 
ATOM 1101 N N   . GLU A 1 158 ? 156.432 152.634 126.785 1.00 61.39  ? 158 GLU A N   1 
ATOM 1102 C CA  . GLU A 1 158 ? 155.148 152.982 126.182 1.00 59.34  ? 158 GLU A CA  1 
ATOM 1103 C C   . GLU A 1 158 ? 153.967 152.334 126.885 1.00 59.60  ? 158 GLU A C   1 
ATOM 1104 O O   . GLU A 1 158 ? 152.987 153.042 127.171 1.00 66.37  ? 158 GLU A O   1 
ATOM 1105 C CB  . GLU A 1 158 ? 155.168 152.626 124.693 1.00 63.51  ? 158 GLU A CB  1 
ATOM 1106 C CG  . GLU A 1 158 ? 156.021 153.556 123.840 1.00 71.90  ? 158 GLU A CG  1 
ATOM 1107 C CD  . GLU A 1 158 ? 155.708 155.023 124.067 1.00 73.86  ? 158 GLU A CD  1 
ATOM 1108 O OE1 . GLU A 1 158 ? 154.541 155.341 124.378 1.00 72.73  ? 158 GLU A OE1 1 
ATOM 1109 O OE2 . GLU A 1 158 ? 156.628 155.857 123.941 1.00 73.28  ? 158 GLU A OE2 1 
ATOM 1110 N N   . PRO A 1 159 ? 153.967 151.034 127.186 1.00 44.96  ? 159 PRO A N   1 
ATOM 1111 C CA  . PRO A 1 159 ? 152.801 150.468 127.882 1.00 45.73  ? 159 PRO A CA  1 
ATOM 1112 C C   . PRO A 1 159 ? 152.515 151.136 129.213 1.00 52.74  ? 159 PRO A C   1 
ATOM 1113 O O   . PRO A 1 159 ? 151.383 151.578 129.444 1.00 57.19  ? 159 PRO A O   1 
ATOM 1114 C CB  . PRO A 1 159 ? 153.174 148.988 128.053 1.00 46.68  ? 159 PRO A CB  1 
ATOM 1115 C CG  . PRO A 1 159 ? 154.638 148.909 127.799 1.00 52.97  ? 159 PRO A CG  1 
ATOM 1116 C CD  . PRO A 1 159 ? 154.945 149.995 126.832 1.00 50.98  ? 159 PRO A CD  1 
ATOM 1117 N N   . VAL A 1 160 ? 153.508 151.238 130.091 1.00 48.13  ? 160 VAL A N   1 
ATOM 1118 C CA  . VAL A 1 160 ? 153.309 151.864 131.395 1.00 49.57  ? 160 VAL A CA  1 
ATOM 1119 C C   . VAL A 1 160 ? 152.966 153.342 131.255 1.00 49.70  ? 160 VAL A C   1 
ATOM 1120 O O   . VAL A 1 160 ? 152.089 153.851 131.959 1.00 56.69  ? 160 VAL A O   1 
ATOM 1121 C CB  . VAL A 1 160 ? 154.557 151.655 132.280 1.00 30.88  ? 160 VAL A CB  1 
ATOM 1122 C CG1 . VAL A 1 160 ? 155.829 152.041 131.547 1.00 49.69  ? 160 VAL A CG1 1 
ATOM 1123 C CG2 . VAL A 1 160 ? 154.430 152.442 133.565 1.00 33.93  ? 160 VAL A CG2 1 
ATOM 1124 N N   . LYS A 1 161 ? 153.646 154.050 130.353 1.00 50.25  ? 161 LYS A N   1 
ATOM 1125 C CA  . LYS A 1 161 ? 153.376 155.471 130.167 1.00 48.21  ? 161 LYS A CA  1 
ATOM 1126 C C   . LYS A 1 161 ? 151.936 155.701 129.728 1.00 57.44  ? 161 LYS A C   1 
ATOM 1127 O O   . LYS A 1 161 ? 151.229 156.552 130.285 1.00 64.96  ? 161 LYS A O   1 
ATOM 1128 C CB  . LYS A 1 161 ? 154.351 156.044 129.140 1.00 44.79  ? 161 LYS A CB  1 
ATOM 1129 C CG  . LYS A 1 161 ? 154.436 157.556 129.133 1.00 49.51  ? 161 LYS A CG  1 
ATOM 1130 C CD  . LYS A 1 161 ? 155.195 158.066 127.917 1.00 54.76  ? 161 LYS A CD  1 
ATOM 1131 C CE  . LYS A 1 161 ? 156.665 157.674 127.957 1.00 60.22  ? 161 LYS A CE  1 
ATOM 1132 N NZ  . LYS A 1 161 ? 157.331 157.890 126.646 1.00 61.30  ? 161 LYS A NZ  1 
ATOM 1133 N N   . LYS A 1 162 ? 151.483 154.947 128.725 1.00 40.10  ? 162 LYS A N   1 
ATOM 1134 C CA  . LYS A 1 162 ? 150.116 155.100 128.245 1.00 43.32  ? 162 LYS A CA  1 
ATOM 1135 C C   . LYS A 1 162 ? 149.112 154.701 129.315 1.00 47.69  ? 162 LYS A C   1 
ATOM 1136 O O   . LYS A 1 162 ? 148.072 155.352 129.473 1.00 56.40  ? 162 LYS A O   1 
ATOM 1137 C CB  . LYS A 1 162 ? 149.912 154.273 126.979 1.00 43.77  ? 162 LYS A CB  1 
ATOM 1138 C CG  . LYS A 1 162 ? 150.399 154.960 125.719 1.00 50.15  ? 162 LYS A CG  1 
ATOM 1139 C CD  . LYS A 1 162 ? 150.021 154.180 124.474 1.00 54.76  ? 162 LYS A CD  1 
ATOM 1140 C CE  . LYS A 1 162 ? 150.830 152.899 124.355 1.00 60.26  ? 162 LYS A CE  1 
ATOM 1141 N NZ  . LYS A 1 162 ? 150.645 152.236 123.034 1.00 61.81  ? 162 LYS A NZ  1 
ATOM 1142 N N   . PHE A 1 163 ? 149.399 153.634 130.064 1.00 31.80  ? 163 PHE A N   1 
ATOM 1143 C CA  . PHE A 1 163 ? 148.480 153.234 131.120 1.00 27.80  ? 163 PHE A CA  1 
ATOM 1144 C C   . PHE A 1 163 ? 148.333 154.333 132.157 1.00 33.41  ? 163 PHE A C   1 
ATOM 1145 O O   . PHE A 1 163 ? 147.223 154.617 132.614 1.00 50.77  ? 163 PHE A O   1 
ATOM 1146 C CB  . PHE A 1 163 ? 148.951 151.945 131.789 1.00 38.79  ? 163 PHE A CB  1 
ATOM 1147 C CG  . PHE A 1 163 ? 148.035 151.471 132.882 1.00 29.68  ? 163 PHE A CG  1 
ATOM 1148 C CD1 . PHE A 1 163 ? 146.903 150.735 132.584 1.00 40.00  ? 163 PHE A CD1 1 
ATOM 1149 C CD2 . PHE A 1 163 ? 148.297 151.775 134.204 1.00 24.86  ? 163 PHE A CD2 1 
ATOM 1150 C CE1 . PHE A 1 163 ? 146.061 150.303 133.583 1.00 39.28  ? 163 PHE A CE1 1 
ATOM 1151 C CE2 . PHE A 1 163 ? 147.456 151.346 135.206 1.00 25.70  ? 163 PHE A CE2 1 
ATOM 1152 C CZ  . PHE A 1 163 ? 146.337 150.610 134.894 1.00 38.74  ? 163 PHE A CZ  1 
ATOM 1153 N N   . PHE A 1 164 ? 149.438 154.969 132.543 1.00 43.08  ? 164 PHE A N   1 
ATOM 1154 C CA  . PHE A 1 164 ? 149.349 155.998 133.573 1.00 45.69  ? 164 PHE A CA  1 
ATOM 1155 C C   . PHE A 1 164 ? 148.698 157.268 133.039 1.00 46.87  ? 164 PHE A C   1 
ATOM 1156 O O   . PHE A 1 164 ? 147.988 157.961 133.775 1.00 46.61  ? 164 PHE A O   1 
ATOM 1157 C CB  . PHE A 1 164 ? 150.732 156.284 134.150 1.00 46.21  ? 164 PHE A CB  1 
ATOM 1158 C CG  . PHE A 1 164 ? 151.119 155.340 135.246 1.00 40.80  ? 164 PHE A CG  1 
ATOM 1159 C CD1 . PHE A 1 164 ? 150.466 155.376 136.463 1.00 37.87  ? 164 PHE A CD1 1 
ATOM 1160 C CD2 . PHE A 1 164 ? 152.111 154.399 135.053 1.00 39.90  ? 164 PHE A CD2 1 
ATOM 1161 C CE1 . PHE A 1 164 ? 150.807 154.505 137.471 1.00 41.89  ? 164 PHE A CE1 1 
ATOM 1162 C CE2 . PHE A 1 164 ? 152.454 153.524 136.061 1.00 41.72  ? 164 PHE A CE2 1 
ATOM 1163 C CZ  . PHE A 1 164 ? 151.801 153.577 137.270 1.00 44.69  ? 164 PHE A CZ  1 
ATOM 1164 N N   . ASP A 1 165 ? 148.902 157.584 131.760 1.00 53.94  ? 165 ASP A N   1 
ATOM 1165 C CA  . ASP A 1 165 ? 148.184 158.714 131.175 1.00 52.25  ? 165 ASP A CA  1 
ATOM 1166 C C   . ASP A 1 165 ? 146.678 158.465 131.184 1.00 59.61  ? 165 ASP A C   1 
ATOM 1167 O O   . ASP A 1 165 ? 145.888 159.329 131.594 1.00 62.34  ? 165 ASP A O   1 
ATOM 1168 C CB  . ASP A 1 165 ? 148.682 158.964 129.754 1.00 51.46  ? 165 ASP A CB  1 
ATOM 1169 C CG  . ASP A 1 165 ? 147.677 159.717 128.913 1.00 67.75  ? 165 ASP A CG  1 
ATOM 1170 O OD1 . ASP A 1 165 ? 146.890 159.061 128.199 1.00 70.09  ? 165 ASP A OD1 1 
ATOM 1171 O OD2 . ASP A 1 165 ? 147.674 160.964 128.965 1.00 64.48  ? 165 ASP A OD2 1 
ATOM 1172 N N   . SER A 1 166 ? 146.262 157.274 130.750 1.00 51.38  ? 166 SER A N   1 
ATOM 1173 C CA  . SER A 1 166 ? 144.842 156.944 130.766 1.00 39.41  ? 166 SER A CA  1 
ATOM 1174 C C   . SER A 1 166 ? 144.303 156.922 132.188 1.00 40.36  ? 166 SER A C   1 
ATOM 1175 O O   . SER A 1 166 ? 143.158 157.316 132.431 1.00 57.66  ? 166 SER A O   1 
ATOM 1176 C CB  . SER A 1 166 ? 144.606 155.599 130.085 1.00 50.63  ? 166 SER A CB  1 
ATOM 1177 O OG  . SER A 1 166 ? 143.221 155.322 129.986 1.00 61.49  ? 166 SER A OG  1 
ATOM 1178 N N   . ALA A 1 167 ? 145.107 156.454 133.142 1.00 37.23  ? 167 ALA A N   1 
ATOM 1179 C CA  . ALA A 1 167 ? 144.679 156.447 134.536 1.00 35.48  ? 167 ALA A CA  1 
ATOM 1180 C C   . ALA A 1 167 ? 144.465 157.864 135.046 1.00 46.16  ? 167 ALA A C   1 
ATOM 1181 O O   . ALA A 1 167 ? 143.505 158.135 135.771 1.00 49.96  ? 167 ALA A O   1 
ATOM 1182 C CB  . ALA A 1 167 ? 145.709 155.714 135.394 1.00 40.32  ? 167 ALA A CB  1 
ATOM 1183 N N   . SER A 1 168 ? 145.360 158.783 134.686 1.00 48.72  ? 168 SER A N   1 
ATOM 1184 C CA  . SER A 1 168 ? 145.178 160.176 135.077 1.00 49.54  ? 168 SER A CA  1 
ATOM 1185 C C   . SER A 1 168 ? 143.887 160.733 134.495 1.00 49.25  ? 168 SER A C   1 
ATOM 1186 O O   . SER A 1 168 ? 143.126 161.427 135.181 1.00 52.47  ? 168 SER A O   1 
ATOM 1187 C CB  . SER A 1 168 ? 146.373 161.008 134.621 1.00 50.43  ? 168 SER A CB  1 
ATOM 1188 O OG  . SER A 1 168 ? 146.244 162.350 135.051 1.00 58.76  ? 168 SER A OG  1 
ATOM 1189 N N   . GLU A 1 169 ? 143.621 160.432 133.223 1.00 46.40  ? 169 GLU A N   1 
ATOM 1190 C CA  . GLU A 1 169 ? 142.376 160.891 132.614 1.00 39.48  ? 169 GLU A CA  1 
ATOM 1191 C C   . GLU A 1 169 ? 141.167 160.311 133.341 1.00 40.36  ? 169 GLU A C   1 
ATOM 1192 O O   . GLU A 1 169 ? 140.166 161.003 133.563 1.00 55.39  ? 169 GLU A O   1 
ATOM 1193 C CB  . GLU A 1 169 ? 142.346 160.517 131.133 1.00 46.20  ? 169 GLU A CB  1 
ATOM 1194 C CG  . GLU A 1 169 ? 143.489 161.105 130.325 1.00 57.51  ? 169 GLU A CG  1 
ATOM 1195 C CD  . GLU A 1 169 ? 143.326 162.591 130.084 1.00 67.98  ? 169 GLU A CD  1 
ATOM 1196 O OE1 . GLU A 1 169 ? 143.430 163.367 131.056 1.00 66.36  ? 169 GLU A OE1 1 
ATOM 1197 O OE2 . GLU A 1 169 ? 143.092 162.983 128.922 1.00 65.44  ? 169 GLU A OE2 1 
ATOM 1198 N N   . VAL A 1 170 ? 141.245 159.037 133.721 1.00 38.60  ? 170 VAL A N   1 
ATOM 1199 C CA  . VAL A 1 170 ? 140.131 158.391 134.411 1.00 36.28  ? 170 VAL A CA  1 
ATOM 1200 C C   . VAL A 1 170 ? 139.903 159.038 135.770 1.00 38.66  ? 170 VAL A C   1 
ATOM 1201 O O   . VAL A 1 170 ? 138.762 159.240 136.198 1.00 44.42  ? 170 VAL A O   1 
ATOM 1202 C CB  . VAL A 1 170 ? 140.389 156.880 134.544 1.00 34.68  ? 170 VAL A CB  1 
ATOM 1203 C CG1 . VAL A 1 170 ? 139.439 156.265 135.562 1.00 34.31  ? 170 VAL A CG1 1 
ATOM 1204 C CG2 . VAL A 1 170 ? 140.254 156.197 133.190 1.00 39.90  ? 170 VAL A CG2 1 
ATOM 1205 N N   . MET A 1 171 ? 140.985 159.349 136.485 1.00 48.55  ? 171 MET A N   1 
ATOM 1206 C CA  . MET A 1 171 ? 140.836 159.975 137.794 1.00 45.58  ? 171 MET A CA  1 
ATOM 1207 C C   . MET A 1 171 ? 140.262 161.379 137.664 1.00 38.58  ? 171 MET A C   1 
ATOM 1208 O O   . MET A 1 171 ? 139.486 161.823 138.517 1.00 36.44  ? 171 MET A O   1 
ATOM 1209 C CB  . MET A 1 171 ? 142.176 160.005 138.528 1.00 42.25  ? 171 MET A CB  1 
ATOM 1210 C CG  . MET A 1 171 ? 142.790 158.630 138.759 1.00 45.42  ? 171 MET A CG  1 
ATOM 1211 S SD  . MET A 1 171 ? 141.800 157.478 139.735 1.00 61.39  ? 171 MET A SD  1 
ATOM 1212 C CE  . MET A 1 171 ? 141.060 158.551 140.955 1.00 43.48  ? 171 MET A CE  1 
ATOM 1213 N N   . PHE A 1 172 ? 140.626 162.095 136.600 1.00 51.72  ? 172 PHE A N   1 
ATOM 1214 C CA  . PHE A 1 172 ? 140.004 163.393 136.360 1.00 41.83  ? 172 PHE A CA  1 
ATOM 1215 C C   . PHE A 1 172 ? 138.521 163.250 136.041 1.00 43.95  ? 172 PHE A C   1 
ATOM 1216 O O   . PHE A 1 172 ? 137.708 164.069 136.484 1.00 57.53  ? 172 PHE A O   1 
ATOM 1217 C CB  . PHE A 1 172 ? 140.727 164.121 135.231 1.00 50.90  ? 172 PHE A CB  1 
ATOM 1218 C CG  . PHE A 1 172 ? 141.987 164.806 135.668 1.00 51.50  ? 172 PHE A CG  1 
ATOM 1219 C CD1 . PHE A 1 172 ? 141.961 165.763 136.666 1.00 48.76  ? 172 PHE A CD1 1 
ATOM 1220 C CD2 . PHE A 1 172 ? 143.200 164.486 135.088 1.00 54.18  ? 172 PHE A CD2 1 
ATOM 1221 C CE1 . PHE A 1 172 ? 143.116 166.390 137.071 1.00 52.40  ? 172 PHE A CE1 1 
ATOM 1222 C CE2 . PHE A 1 172 ? 144.359 165.111 135.490 1.00 54.83  ? 172 PHE A CE2 1 
ATOM 1223 C CZ  . PHE A 1 172 ? 144.317 166.064 136.482 1.00 60.98  ? 172 PHE A CZ  1 
ATOM 1224 N N   . LYS A 1 173 ? 138.146 162.218 135.286 1.00 46.64  ? 173 LYS A N   1 
ATOM 1225 C CA  . LYS A 1 173 ? 136.729 161.950 135.056 1.00 41.35  ? 173 LYS A CA  1 
ATOM 1226 C C   . LYS A 1 173 ? 136.012 161.664 136.369 1.00 35.30  ? 173 LYS A C   1 
ATOM 1227 O O   . LYS A 1 173 ? 134.886 162.122 136.591 1.00 38.90  ? 173 LYS A O   1 
ATOM 1228 C CB  . LYS A 1 173 ? 136.567 160.777 134.090 1.00 51.96  ? 173 LYS A CB  1 
ATOM 1229 C CG  . LYS A 1 173 ? 135.121 160.414 133.762 1.00 49.87  ? 173 LYS A CG  1 
ATOM 1230 C CD  . LYS A 1 173 ? 134.296 161.595 133.266 1.00 53.15  ? 173 LYS A CD  1 
ATOM 1231 C CE  . LYS A 1 173 ? 134.861 162.206 131.993 1.00 51.29  ? 173 LYS A CE  1 
ATOM 1232 N NZ  . LYS A 1 173 ? 134.216 163.509 131.676 1.00 48.24  ? 173 LYS A NZ  1 
ATOM 1233 N N   . ILE A 1 174 ? 136.649 160.894 137.251 1.00 44.77  ? 174 ILE A N   1 
ATOM 1234 C CA  . ILE A 1 174 ? 136.053 160.601 138.553 1.00 36.52  ? 174 ILE A CA  1 
ATOM 1235 C C   . ILE A 1 174 ? 135.854 161.888 139.340 1.00 42.74  ? 174 ILE A C   1 
ATOM 1236 O O   . ILE A 1 174 ? 134.796 162.118 139.936 1.00 54.64  ? 174 ILE A O   1 
ATOM 1237 C CB  . ILE A 1 174 ? 136.921 159.597 139.331 1.00 43.93  ? 174 ILE A CB  1 
ATOM 1238 C CG1 . ILE A 1 174 ? 136.878 158.223 138.666 1.00 46.08  ? 174 ILE A CG1 1 
ATOM 1239 C CG2 . ILE A 1 174 ? 136.446 159.495 140.769 1.00 44.41  ? 174 ILE A CG2 1 
ATOM 1240 C CD1 . ILE A 1 174 ? 137.990 157.301 139.109 1.00 45.71  ? 174 ILE A CD1 1 
ATOM 1241 N N   . THR A 1 175 ? 136.873 162.748 139.355 1.00 58.15  ? 175 THR A N   1 
ATOM 1242 C CA  . THR A 1 175 ? 136.742 164.039 140.021 1.00 47.31  ? 175 THR A CA  1 
ATOM 1243 C C   . THR A 1 175 ? 135.587 164.834 139.433 1.00 46.52  ? 175 THR A C   1 
ATOM 1244 O O   . THR A 1 175 ? 134.872 165.535 140.154 1.00 60.30  ? 175 THR A O   1 
ATOM 1245 C CB  . THR A 1 175 ? 138.044 164.831 139.901 1.00 49.73  ? 175 THR A CB  1 
ATOM 1246 O OG1 . THR A 1 175 ? 139.154 163.988 140.231 1.00 61.47  ? 175 THR A OG1 1 
ATOM 1247 C CG2 . THR A 1 175 ? 138.027 166.031 140.832 1.00 44.65  ? 175 THR A CG2 1 
ATOM 1248 N N   . ASP A 1 176 ? 135.394 164.740 138.119 1.00 54.96  ? 176 ASP A N   1 
ATOM 1249 C CA  . ASP A 1 176 ? 134.250 165.396 137.495 1.00 56.35  ? 176 ASP A CA  1 
ATOM 1250 C C   . ASP A 1 176 ? 132.941 164.816 138.016 1.00 52.93  ? 176 ASP A C   1 
ATOM 1251 O O   . ASP A 1 176 ? 131.974 165.548 138.253 1.00 58.04  ? 176 ASP A O   1 
ATOM 1252 C CB  . ASP A 1 176 ? 134.333 165.257 135.977 1.00 61.02  ? 176 ASP A CB  1 
ATOM 1253 C CG  . ASP A 1 176 ? 133.564 166.341 135.252 1.00 67.58  ? 176 ASP A CG  1 
ATOM 1254 O OD1 . ASP A 1 176 ? 132.852 166.017 134.278 1.00 72.35  ? 176 ASP A OD1 1 
ATOM 1255 O OD2 . ASP A 1 176 ? 133.670 167.518 135.655 1.00 67.99  ? 176 ASP A OD2 1 
ATOM 1256 N N   . ILE A 1 177 ? 132.890 163.496 138.193 1.00 49.77  ? 177 ILE A N   1 
ATOM 1257 C CA  . ILE A 1 177 ? 131.659 162.849 138.645 1.00 45.02  ? 177 ILE A CA  1 
ATOM 1258 C C   . ILE A 1 177 ? 131.301 163.310 140.053 1.00 50.56  ? 177 ILE A C   1 
ATOM 1259 O O   . ILE A 1 177 ? 130.165 163.711 140.325 1.00 59.73  ? 177 ILE A O   1 
ATOM 1260 C CB  . ILE A 1 177 ? 131.799 161.319 138.580 1.00 47.61  ? 177 ILE A CB  1 
ATOM 1261 C CG1 . ILE A 1 177 ? 131.804 160.844 137.127 1.00 55.53  ? 177 ILE A CG1 1 
ATOM 1262 C CG2 . ILE A 1 177 ? 130.671 160.651 139.348 1.00 46.03  ? 177 ILE A CG2 1 
ATOM 1263 C CD1 . ILE A 1 177 ? 132.424 159.481 136.937 1.00 53.69  ? 177 ILE A CD1 1 
ATOM 1264 N N   . VAL A 1 178 ? 132.267 163.253 140.973 1.00 54.19  ? 178 VAL A N   1 
ATOM 1265 C CA  . VAL A 1 178 ? 131.973 163.577 142.367 1.00 51.74  ? 178 VAL A CA  1 
ATOM 1266 C C   . VAL A 1 178 ? 131.629 165.053 142.511 1.00 52.70  ? 178 VAL A C   1 
ATOM 1267 O O   . VAL A 1 178 ? 130.781 165.430 143.329 1.00 62.51  ? 178 VAL A O   1 
ATOM 1268 C CB  . VAL A 1 178 ? 133.150 163.178 143.279 1.00 44.36  ? 178 VAL A CB  1 
ATOM 1269 C CG1 . VAL A 1 178 ? 133.567 161.742 143.015 1.00 44.91  ? 178 VAL A CG1 1 
ATOM 1270 C CG2 . VAL A 1 178 ? 134.324 164.118 143.092 1.00 47.04  ? 178 VAL A CG2 1 
ATOM 1271 N N   . MET A 1 179 ? 132.273 165.912 141.720 1.00 53.38  ? 179 MET A N   1 
ATOM 1272 C CA  . MET A 1 179 ? 132.023 167.343 141.839 1.00 49.35  ? 179 MET A CA  1 
ATOM 1273 C C   . MET A 1 179 ? 130.573 167.690 141.533 1.00 53.50  ? 179 MET A C   1 
ATOM 1274 O O   . MET A 1 179 ? 130.098 168.759 141.929 1.00 62.19  ? 179 MET A O   1 
ATOM 1275 C CB  . MET A 1 179 ? 132.961 168.118 140.915 1.00 53.28  ? 179 MET A CB  1 
ATOM 1276 C CG  . MET A 1 179 ? 134.373 168.282 141.453 1.00 55.55  ? 179 MET A CG  1 
ATOM 1277 S SD  . MET A 1 179 ? 134.439 169.159 143.026 1.00 76.43  ? 179 MET A SD  1 
ATOM 1278 C CE  . MET A 1 179 ? 134.425 170.857 142.463 1.00 64.79  ? 179 MET A CE  1 
ATOM 1279 N N   . LYS A 1 180 ? 129.853 166.814 140.828 1.00 51.60  ? 180 LYS A N   1 
ATOM 1280 C CA  . LYS A 1 180 ? 128.426 167.043 140.639 1.00 49.63  ? 180 LYS A CA  1 
ATOM 1281 C C   . LYS A 1 180 ? 127.687 167.025 141.968 1.00 53.95  ? 180 LYS A C   1 
ATOM 1282 O O   . LYS A 1 180 ? 126.647 167.677 142.112 1.00 61.85  ? 180 LYS A O   1 
ATOM 1283 C CB  . LYS A 1 180 ? 127.842 165.997 139.692 1.00 53.84  ? 180 LYS A CB  1 
ATOM 1284 C CG  . LYS A 1 180 ? 128.195 166.224 138.234 1.00 57.70  ? 180 LYS A CG  1 
ATOM 1285 C CD  . LYS A 1 180 ? 127.710 165.079 137.364 1.00 60.53  ? 180 LYS A CD  1 
ATOM 1286 C CE  . LYS A 1 180 ? 128.071 165.299 135.907 1.00 63.44  ? 180 LYS A CE  1 
ATOM 1287 N NZ  . LYS A 1 180 ? 127.538 164.217 135.033 1.00 69.77  ? 180 LYS A NZ  1 
ATOM 1288 N N   . PHE A 1 181 ? 128.205 166.283 142.945 1.00 53.76  ? 181 PHE A N   1 
ATOM 1289 C CA  . PHE A 1 181 ? 127.671 166.289 144.300 1.00 48.46  ? 181 PHE A CA  1 
ATOM 1290 C C   . PHE A 1 181 ? 128.171 167.471 145.117 1.00 49.17  ? 181 PHE A C   1 
ATOM 1291 O O   . PHE A 1 181 ? 127.728 167.648 146.256 1.00 59.81  ? 181 PHE A O   1 
ATOM 1292 C CB  . PHE A 1 181 ? 128.049 164.981 144.999 1.00 48.19  ? 181 PHE A CB  1 
ATOM 1293 C CG  . PHE A 1 181 ? 127.279 164.714 146.258 1.00 46.41  ? 181 PHE A CG  1 
ATOM 1294 C CD1 . PHE A 1 181 ? 125.976 164.256 146.206 1.00 52.18  ? 181 PHE A CD1 1 
ATOM 1295 C CD2 . PHE A 1 181 ? 127.868 164.901 147.495 1.00 51.06  ? 181 PHE A CD2 1 
ATOM 1296 C CE1 . PHE A 1 181 ? 125.270 164.003 147.363 1.00 52.04  ? 181 PHE A CE1 1 
ATOM 1297 C CE2 . PHE A 1 181 ? 127.167 164.648 148.654 1.00 49.41  ? 181 PHE A CE2 1 
ATOM 1298 C CZ  . PHE A 1 181 ? 125.867 164.198 148.588 1.00 52.31  ? 181 PHE A CZ  1 
ATOM 1299 N N   . ALA A 1 182 ? 129.076 168.278 144.565 1.00 53.69  ? 182 ALA A N   1 
ATOM 1300 C CA  . ALA A 1 182 ? 129.702 169.359 145.323 1.00 46.06  ? 182 ALA A CA  1 
ATOM 1301 C C   . ALA A 1 182 ? 128.708 170.352 145.902 1.00 49.10  ? 182 ALA A C   1 
ATOM 1302 O O   . ALA A 1 182 ? 128.894 170.769 147.054 1.00 57.90  ? 182 ALA A O   1 
ATOM 1303 C CB  . ALA A 1 182 ? 130.721 170.078 144.430 1.00 52.64  ? 182 ALA A CB  1 
ATOM 1304 N N   . PRO A 1 183 ? 127.676 170.797 145.181 1.00 56.95  ? 183 PRO A N   1 
ATOM 1305 C CA  . PRO A 1 183 ? 126.745 171.763 145.789 1.00 55.67  ? 183 PRO A CA  1 
ATOM 1306 C C   . PRO A 1 183 ? 126.147 171.273 147.096 1.00 54.14  ? 183 PRO A C   1 
ATOM 1307 O O   . PRO A 1 183 ? 126.105 172.021 148.079 1.00 57.59  ? 183 PRO A O   1 
ATOM 1308 C CB  . PRO A 1 183 ? 125.682 171.946 144.700 1.00 53.24  ? 183 PRO A CB  1 
ATOM 1309 C CG  . PRO A 1 183 ? 126.364 171.594 143.434 1.00 57.22  ? 183 PRO A CG  1 
ATOM 1310 C CD  . PRO A 1 183 ? 127.351 170.526 143.771 1.00 57.96  ? 183 PRO A CD  1 
ATOM 1311 N N   . TYR A 1 184 ? 125.730 170.008 147.149 1.00 52.02  ? 184 TYR A N   1 
ATOM 1312 C CA  . TYR A 1 184 ? 125.074 169.496 148.348 1.00 51.70  ? 184 TYR A CA  1 
ATOM 1313 C C   . TYR A 1 184 ? 126.078 169.245 149.465 1.00 51.31  ? 184 TYR A C   1 
ATOM 1314 O O   . TYR A 1 184 ? 125.787 169.506 150.638 1.00 60.98  ? 184 TYR A O   1 
ATOM 1315 C CB  . TYR A 1 184 ? 124.302 168.225 148.004 1.00 48.18  ? 184 TYR A CB  1 
ATOM 1316 C CG  . TYR A 1 184 ? 123.563 168.337 146.693 1.00 49.19  ? 184 TYR A CG  1 
ATOM 1317 C CD1 . TYR A 1 184 ? 122.372 169.039 146.607 1.00 50.28  ? 184 TYR A CD1 1 
ATOM 1318 C CD2 . TYR A 1 184 ? 124.069 167.766 145.537 1.00 53.36  ? 184 TYR A CD2 1 
ATOM 1319 C CE1 . TYR A 1 184 ? 121.698 169.155 145.411 1.00 49.95  ? 184 TYR A CE1 1 
ATOM 1320 C CE2 . TYR A 1 184 ? 123.403 167.878 144.336 1.00 54.09  ? 184 TYR A CE2 1 
ATOM 1321 C CZ  . TYR A 1 184 ? 122.219 168.574 144.279 1.00 55.77  ? 184 TYR A CZ  1 
ATOM 1322 O OH  . TYR A 1 184 ? 121.549 168.688 143.085 1.00 69.04  ? 184 TYR A OH  1 
ATOM 1323 N N   . GLY A 1 185 ? 127.266 168.748 149.127 1.00 51.29  ? 185 GLY A N   1 
ATOM 1324 C CA  . GLY A 1 185 ? 128.297 168.594 150.139 1.00 51.23  ? 185 GLY A CA  1 
ATOM 1325 C C   . GLY A 1 185 ? 128.700 169.919 150.757 1.00 47.30  ? 185 GLY A C   1 
ATOM 1326 O O   . GLY A 1 185 ? 128.875 170.022 151.973 1.00 51.76  ? 185 GLY A O   1 
ATOM 1327 N N   . VAL A 1 186 ? 128.855 170.951 149.926 1.00 44.66  ? 186 VAL A N   1 
ATOM 1328 C CA  . VAL A 1 186 ? 129.206 172.271 150.435 1.00 48.55  ? 186 VAL A CA  1 
ATOM 1329 C C   . VAL A 1 186 ? 128.064 172.840 151.264 1.00 52.25  ? 186 VAL A C   1 
ATOM 1330 O O   . VAL A 1 186 ? 128.289 173.484 152.295 1.00 61.56  ? 186 VAL A O   1 
ATOM 1331 C CB  . VAL A 1 186 ? 129.583 173.205 149.273 1.00 40.45  ? 186 VAL A CB  1 
ATOM 1332 C CG1 . VAL A 1 186 ? 129.582 174.652 149.729 1.00 49.13  ? 186 VAL A CG1 1 
ATOM 1333 C CG2 . VAL A 1 186 ? 130.939 172.819 148.711 1.00 48.32  ? 186 VAL A CG2 1 
ATOM 1334 N N   . PHE A 1 187 ? 126.824 172.623 150.828 1.00 51.47  ? 187 PHE A N   1 
ATOM 1335 C CA  . PHE A 1 187 ? 125.679 173.031 151.631 1.00 46.33  ? 187 PHE A CA  1 
ATOM 1336 C C   . PHE A 1 187 ? 125.742 172.400 153.014 1.00 48.08  ? 187 PHE A C   1 
ATOM 1337 O O   . PHE A 1 187 ? 125.584 173.084 154.031 1.00 66.66  ? 187 PHE A O   1 
ATOM 1338 C CB  . PHE A 1 187 ? 124.388 172.641 150.914 1.00 50.86  ? 187 PHE A CB  1 
ATOM 1339 C CG  . PHE A 1 187 ? 123.177 172.641 151.796 1.00 48.76  ? 187 PHE A CG  1 
ATOM 1340 C CD1 . PHE A 1 187 ? 122.531 173.821 152.107 1.00 52.87  ? 187 PHE A CD1 1 
ATOM 1341 C CD2 . PHE A 1 187 ? 122.680 171.458 152.307 1.00 53.09  ? 187 PHE A CD2 1 
ATOM 1342 C CE1 . PHE A 1 187 ? 121.415 173.821 152.916 1.00 55.95  ? 187 PHE A CE1 1 
ATOM 1343 C CE2 . PHE A 1 187 ? 121.566 171.453 153.115 1.00 57.65  ? 187 PHE A CE2 1 
ATOM 1344 C CZ  . PHE A 1 187 ? 120.933 172.636 153.420 1.00 60.64  ? 187 PHE A CZ  1 
ATOM 1345 N N   . ALA A 1 188 ? 125.985 171.091 153.067 1.00 46.44  ? 188 ALA A N   1 
ATOM 1346 C CA  . ALA A 1 188 ? 126.038 170.396 154.347 1.00 45.32  ? 188 ALA A CA  1 
ATOM 1347 C C   . ALA A 1 188 ? 127.177 170.918 155.211 1.00 49.19  ? 188 ALA A C   1 
ATOM 1348 O O   . ALA A 1 188 ? 127.002 171.160 156.411 1.00 57.21  ? 188 ALA A O   1 
ATOM 1349 C CB  . ALA A 1 188 ? 126.186 168.895 154.115 1.00 60.30  ? 188 ALA A CB  1 
ATOM 1350 N N   . LEU A 1 189 ? 128.358 171.094 154.617 1.00 58.01  ? 189 LEU A N   1 
ATOM 1351 C CA  . LEU A 1 189 ? 129.503 171.572 155.384 1.00 52.04  ? 189 LEU A CA  1 
ATOM 1352 C C   . LEU A 1 189 ? 129.239 172.953 155.963 1.00 50.08  ? 189 LEU A C   1 
ATOM 1353 O O   . LEU A 1 189 ? 129.493 173.197 157.149 1.00 60.56  ? 189 LEU A O   1 
ATOM 1354 C CB  . LEU A 1 189 ? 130.750 171.600 154.503 1.00 49.25  ? 189 LEU A CB  1 
ATOM 1355 C CG  . LEU A 1 189 ? 131.387 170.245 154.205 1.00 47.96  ? 189 LEU A CG  1 
ATOM 1356 C CD1 . LEU A 1 189 ? 132.262 170.331 152.970 1.00 53.87  ? 189 LEU A CD1 1 
ATOM 1357 C CD2 . LEU A 1 189 ? 132.192 169.771 155.399 1.00 54.00  ? 189 LEU A CD2 1 
ATOM 1358 N N   . MET A 1 190 ? 128.731 173.873 155.142 1.00 48.03  ? 190 MET A N   1 
ATOM 1359 C CA  . MET A 1 190 ? 128.473 175.223 155.625 1.00 49.41  ? 190 MET A CA  1 
ATOM 1360 C C   . MET A 1 190 ? 127.391 175.226 156.694 1.00 58.03  ? 190 MET A C   1 
ATOM 1361 O O   . MET A 1 190 ? 127.521 175.919 157.710 1.00 68.22  ? 190 MET A O   1 
ATOM 1362 C CB  . MET A 1 190 ? 128.073 176.126 154.461 1.00 50.58  ? 190 MET A CB  1 
ATOM 1363 C CG  . MET A 1 190 ? 129.205 176.503 153.512 1.00 67.30  ? 190 MET A CG  1 
ATOM 1364 S SD  . MET A 1 190 ? 130.858 176.503 154.232 1.00 72.08  ? 190 MET A SD  1 
ATOM 1365 C CE  . MET A 1 190 ? 130.850 178.079 155.078 1.00 58.59  ? 190 MET A CE  1 
ATOM 1366 N N   . ALA A 1 191 ? 126.315 174.466 156.489 1.00 56.90  ? 191 ALA A N   1 
ATOM 1367 C CA  . ALA A 1 191 ? 125.267 174.402 157.498 1.00 55.18  ? 191 ALA A CA  1 
ATOM 1368 C C   . ALA A 1 191 ? 125.826 173.900 158.820 1.00 59.38  ? 191 ALA A C   1 
ATOM 1369 O O   . ALA A 1 191 ? 125.596 174.502 159.875 1.00 64.42  ? 191 ALA A O   1 
ATOM 1370 C CB  . ALA A 1 191 ? 124.129 173.503 157.016 1.00 58.57  ? 191 ALA A CB  1 
ATOM 1371 N N   . TRP A 1 192 ? 126.587 172.806 158.779 1.00 58.18  ? 192 TRP A N   1 
ATOM 1372 C CA  . TRP A 1 192 ? 127.137 172.245 160.006 1.00 59.01  ? 192 TRP A CA  1 
ATOM 1373 C C   . TRP A 1 192 ? 128.065 173.235 160.695 1.00 59.26  ? 192 TRP A C   1 
ATOM 1374 O O   . TRP A 1 192 ? 127.992 173.426 161.913 1.00 67.92  ? 192 TRP A O   1 
ATOM 1375 C CB  . TRP A 1 192 ? 127.875 170.943 159.698 1.00 64.46  ? 192 TRP A CB  1 
ATOM 1376 C CG  . TRP A 1 192 ? 128.704 170.452 160.836 1.00 68.09  ? 192 TRP A CG  1 
ATOM 1377 C CD1 . TRP A 1 192 ? 128.255 169.949 162.019 1.00 62.77  ? 192 TRP A CD1 1 
ATOM 1378 C CD2 . TRP A 1 192 ? 130.133 170.421 160.903 1.00 66.36  ? 192 TRP A CD2 1 
ATOM 1379 N NE1 . TRP A 1 192 ? 129.314 169.605 162.820 1.00 60.07  ? 192 TRP A NE1 1 
ATOM 1380 C CE2 . TRP A 1 192 ? 130.479 169.885 162.157 1.00 67.24  ? 192 TRP A CE2 1 
ATOM 1381 C CE3 . TRP A 1 192 ? 131.153 170.793 160.024 1.00 65.15  ? 192 TRP A CE3 1 
ATOM 1382 C CZ2 . TRP A 1 192 ? 131.801 169.713 162.553 1.00 69.73  ? 192 TRP A CZ2 1 
ATOM 1383 C CZ3 . TRP A 1 192 ? 132.463 170.621 160.419 1.00 64.88  ? 192 TRP A CZ3 1 
ATOM 1384 C CH2 . TRP A 1 192 ? 132.776 170.086 161.672 1.00 63.89  ? 192 TRP A CH2 1 
ATOM 1385 N N   . THR A 1 193 ? 128.946 173.880 159.930 1.00 52.36  ? 193 THR A N   1 
ATOM 1386 C CA  . THR A 1 193 ? 129.916 174.791 160.528 1.00 53.03  ? 193 THR A CA  1 
ATOM 1387 C C   . THR A 1 193 ? 129.222 175.984 161.169 1.00 63.78  ? 193 THR A C   1 
ATOM 1388 O O   . THR A 1 193 ? 129.521 176.359 162.311 1.00 75.21  ? 193 THR A O   1 
ATOM 1389 C CB  . THR A 1 193 ? 130.915 175.257 159.469 1.00 61.46  ? 193 THR A CB  1 
ATOM 1390 O OG1 . THR A 1 193 ? 131.498 174.120 158.823 1.00 70.29  ? 193 THR A OG1 1 
ATOM 1391 C CG2 . THR A 1 193 ? 132.012 176.092 160.102 1.00 58.57  ? 193 THR A CG2 1 
ATOM 1392 N N   . VAL A 1 194 ? 128.293 176.607 160.439 1.00 57.42  ? 194 VAL A N   1 
ATOM 1393 C CA  . VAL A 1 194 ? 127.622 177.791 160.954 1.00 55.45  ? 194 VAL A CA  1 
ATOM 1394 C C   . VAL A 1 194 ? 126.676 177.448 162.093 1.00 57.25  ? 194 VAL A C   1 
ATOM 1395 O O   . VAL A 1 194 ? 126.374 178.314 162.921 1.00 58.78  ? 194 VAL A O   1 
ATOM 1396 C CB  . VAL A 1 194 ? 126.876 178.515 159.821 1.00 53.30  ? 194 VAL A CB  1 
ATOM 1397 C CG1 . VAL A 1 194 ? 126.149 179.732 160.362 1.00 57.36  ? 194 VAL A CG1 1 
ATOM 1398 C CG2 . VAL A 1 194 ? 127.848 178.923 158.727 1.00 58.11  ? 194 VAL A CG2 1 
ATOM 1399 N N   . GLY A 1 195 ? 126.192 176.211 162.162 1.00 72.84  ? 195 GLY A N   1 
ATOM 1400 C CA  . GLY A 1 195 ? 125.398 175.798 163.299 1.00 74.46  ? 195 GLY A CA  1 
ATOM 1401 C C   . GLY A 1 195 ? 126.248 175.547 164.525 1.00 70.35  ? 195 GLY A C   1 
ATOM 1402 O O   . GLY A 1 195 ? 125.879 175.934 165.637 1.00 67.88  ? 195 GLY A O   1 
ATOM 1403 N N   . LYS A 1 196 ? 127.399 174.901 164.333 1.00 79.53  ? 196 LYS A N   1 
ATOM 1404 C CA  . LYS A 1 196 ? 128.244 174.551 165.468 1.00 82.28  ? 196 LYS A CA  1 
ATOM 1405 C C   . LYS A 1 196 ? 128.890 175.787 166.078 1.00 81.94  ? 196 LYS A C   1 
ATOM 1406 O O   . LYS A 1 196 ? 128.900 175.954 167.303 1.00 84.23  ? 196 LYS A O   1 
ATOM 1407 C CB  . LYS A 1 196 ? 129.313 173.546 165.039 1.00 84.11  ? 196 LYS A CB  1 
ATOM 1408 C CG  . LYS A 1 196 ? 130.267 173.167 166.157 1.00 82.52  ? 196 LYS A CG  1 
ATOM 1409 C CD  . LYS A 1 196 ? 130.997 171.869 165.861 1.00 85.02  ? 196 LYS A CD  1 
ATOM 1410 C CE  . LYS A 1 196 ? 131.881 171.456 167.027 1.00 84.95  ? 196 LYS A CE  1 
ATOM 1411 N NZ  . LYS A 1 196 ? 132.418 170.079 166.865 1.00 80.34  ? 196 LYS A NZ  1 
ATOM 1412 N N   . TYR A 1 197 ? 129.439 176.668 165.242 1.00 82.04  ? 197 TYR A N   1 
ATOM 1413 C CA  . TYR A 1 197 ? 130.205 177.813 165.739 1.00 83.24  ? 197 TYR A CA  1 
ATOM 1414 C C   . TYR A 1 197 ? 129.301 179.043 165.824 1.00 84.71  ? 197 TYR A C   1 
ATOM 1415 O O   . TYR A 1 197 ? 129.303 179.932 164.972 1.00 81.32  ? 197 TYR A O   1 
ATOM 1416 C CB  . TYR A 1 197 ? 131.420 178.053 164.854 1.00 83.74  ? 197 TYR A CB  1 
ATOM 1417 C CG  . TYR A 1 197 ? 132.404 176.904 164.888 1.00 82.72  ? 197 TYR A CG  1 
ATOM 1418 C CD1 . TYR A 1 197 ? 132.215 175.782 164.095 1.00 80.31  ? 197 TYR A CD1 1 
ATOM 1419 C CD2 . TYR A 1 197 ? 133.510 176.935 165.723 1.00 85.60  ? 197 TYR A CD2 1 
ATOM 1420 C CE1 . TYR A 1 197 ? 133.104 174.728 164.127 1.00 83.43  ? 197 TYR A CE1 1 
ATOM 1421 C CE2 . TYR A 1 197 ? 134.404 175.886 165.762 1.00 85.97  ? 197 TYR A CE2 1 
ATOM 1422 C CZ  . TYR A 1 197 ? 134.197 174.785 164.962 1.00 86.63  ? 197 TYR A CZ  1 
ATOM 1423 O OH  . TYR A 1 197 ? 135.086 173.737 164.997 1.00 89.97  ? 197 TYR A OH  1 
ATOM 1424 N N   . GLY A 1 198 ? 128.519 179.078 166.900 1.00 102.73 ? 198 GLY A N   1 
ATOM 1425 C CA  . GLY A 1 198 ? 127.589 180.165 167.118 1.00 102.46 ? 198 GLY A CA  1 
ATOM 1426 C C   . GLY A 1 198 ? 128.278 181.441 167.565 1.00 107.30 ? 198 GLY A C   1 
ATOM 1427 O O   . GLY A 1 198 ? 129.426 181.455 168.006 1.00 109.55 ? 198 GLY A O   1 
ATOM 1428 N N   . LEU A 1 199 ? 127.527 182.542 167.469 1.00 115.11 ? 199 LEU A N   1 
ATOM 1429 C CA  . LEU A 1 199 ? 128.101 183.862 167.714 1.00 113.76 ? 199 LEU A CA  1 
ATOM 1430 C C   . LEU A 1 199 ? 128.722 183.956 169.102 1.00 109.62 ? 199 LEU A C   1 
ATOM 1431 O O   . LEU A 1 199 ? 129.690 184.698 169.307 1.00 108.11 ? 199 LEU A O   1 
ATOM 1432 C CB  . LEU A 1 199 ? 127.030 184.939 167.538 1.00 115.11 ? 199 LEU A CB  1 
ATOM 1433 C CG  . LEU A 1 199 ? 126.635 185.320 166.107 1.00 116.38 ? 199 LEU A CG  1 
ATOM 1434 C CD1 . LEU A 1 199 ? 127.854 185.690 165.271 1.00 112.28 ? 199 LEU A CD1 1 
ATOM 1435 C CD2 . LEU A 1 199 ? 125.851 184.196 165.441 1.00 112.90 ? 199 LEU A CD2 1 
ATOM 1436 N N   . ASP A 1 200 ? 128.183 183.212 170.070 1.00 112.78 ? 200 ASP A N   1 
ATOM 1437 C CA  . ASP A 1 200 ? 128.729 183.265 171.423 1.00 114.93 ? 200 ASP A CA  1 
ATOM 1438 C C   . ASP A 1 200 ? 130.192 182.843 171.439 1.00 114.63 ? 200 ASP A C   1 
ATOM 1439 O O   . ASP A 1 200 ? 131.006 183.421 172.168 1.00 111.93 ? 200 ASP A O   1 
ATOM 1440 C CB  . ASP A 1 200 ? 127.907 182.380 172.361 1.00 113.49 ? 200 ASP A CB  1 
ATOM 1441 C CG  . ASP A 1 200 ? 126.415 182.509 172.128 1.00 115.23 ? 200 ASP A CG  1 
ATOM 1442 O OD1 . ASP A 1 200 ? 125.973 182.311 170.977 1.00 116.27 ? 200 ASP A OD1 1 
ATOM 1443 O OD2 . ASP A 1 200 ? 125.686 182.810 173.096 1.00 113.04 ? 200 ASP A OD2 1 
ATOM 1444 N N   . VAL A 1 201 ? 130.545 181.831 170.643 1.00 106.36 ? 201 VAL A N   1 
ATOM 1445 C CA  . VAL A 1 201 ? 131.935 181.391 170.584 1.00 105.56 ? 201 VAL A CA  1 
ATOM 1446 C C   . VAL A 1 201 ? 132.810 182.456 169.935 1.00 102.74 ? 201 VAL A C   1 
ATOM 1447 O O   . VAL A 1 201 ? 133.968 182.641 170.329 1.00 100.00 ? 201 VAL A O   1 
ATOM 1448 C CB  . VAL A 1 201 ? 132.048 180.048 169.837 1.00 105.97 ? 201 VAL A CB  1 
ATOM 1449 C CG1 . VAL A 1 201 ? 133.332 179.337 170.221 1.00 102.55 ? 201 VAL A CG1 1 
ATOM 1450 C CG2 . VAL A 1 201 ? 130.852 179.158 170.138 1.00 102.86 ? 201 VAL A CG2 1 
ATOM 1451 N N   . LEU A 1 202 ? 132.287 183.163 168.931 1.00 96.93  ? 202 LEU A N   1 
ATOM 1452 C CA  . LEU A 1 202 ? 133.091 184.144 168.210 1.00 96.99  ? 202 LEU A CA  1 
ATOM 1453 C C   . LEU A 1 202 ? 133.237 185.445 168.990 1.00 99.58  ? 202 LEU A C   1 
ATOM 1454 O O   . LEU A 1 202 ? 134.217 186.174 168.800 1.00 101.34 ? 202 LEU A O   1 
ATOM 1455 C CB  . LEU A 1 202 ? 132.469 184.427 166.843 1.00 97.86  ? 202 LEU A CB  1 
ATOM 1456 C CG  . LEU A 1 202 ? 132.453 183.292 165.811 1.00 101.49 ? 202 LEU A CG  1 
ATOM 1457 C CD1 . LEU A 1 202 ? 133.680 182.401 165.893 1.00 96.38  ? 202 LEU A CD1 1 
ATOM 1458 C CD2 . LEU A 1 202 ? 131.202 182.447 165.955 1.00 102.32 ? 202 LEU A CD2 1 
ATOM 1459 N N   . ALA A 1 203 ? 132.280 185.754 169.861 1.00 102.51 ? 203 ALA A N   1 
ATOM 1460 C CA  . ALA A 1 203 ? 132.280 187.044 170.548 1.00 100.76 ? 203 ALA A CA  1 
ATOM 1461 C C   . ALA A 1 203 ? 133.591 187.348 171.259 1.00 99.23  ? 203 ALA A C   1 
ATOM 1462 O O   . ALA A 1 203 ? 134.122 188.455 171.078 1.00 97.72  ? 203 ALA A O   1 
ATOM 1463 C CB  . ALA A 1 203 ? 131.108 187.090 171.537 1.00 97.10  ? 203 ALA A CB  1 
ATOM 1464 N N   . PRO A 1 204 ? 134.164 186.446 172.061 1.00 101.90 ? 204 PRO A N   1 
ATOM 1465 C CA  . PRO A 1 204 ? 135.424 186.783 172.740 1.00 103.26 ? 204 PRO A CA  1 
ATOM 1466 C C   . PRO A 1 204 ? 136.626 186.841 171.814 1.00 105.26 ? 204 PRO A C   1 
ATOM 1467 O O   . PRO A 1 204 ? 137.553 187.615 172.086 1.00 102.09 ? 204 PRO A O   1 
ATOM 1468 C CB  . PRO A 1 204 ? 135.574 185.664 173.778 1.00 101.74 ? 204 PRO A CB  1 
ATOM 1469 C CG  . PRO A 1 204 ? 134.809 184.523 173.219 1.00 101.26 ? 204 PRO A CG  1 
ATOM 1470 C CD  . PRO A 1 204 ? 133.664 185.117 172.453 1.00 99.42  ? 204 PRO A CD  1 
ATOM 1471 N N   . LEU A 1 205 ? 136.645 186.061 170.733 1.00 99.14  ? 205 LEU A N   1 
ATOM 1472 C CA  . LEU A 1 205 ? 137.800 185.977 169.846 1.00 91.74  ? 205 LEU A CA  1 
ATOM 1473 C C   . LEU A 1 205 ? 137.567 186.665 168.506 1.00 92.35  ? 205 LEU A C   1 
ATOM 1474 O O   . LEU A 1 205 ? 138.329 186.429 167.559 1.00 94.84  ? 205 LEU A O   1 
ATOM 1475 C CB  . LEU A 1 205 ? 138.183 184.511 169.628 1.00 90.50  ? 205 LEU A CB  1 
ATOM 1476 C CG  . LEU A 1 205 ? 139.158 183.935 170.656 1.00 92.89  ? 205 LEU A CG  1 
ATOM 1477 C CD1 . LEU A 1 205 ? 138.582 184.024 172.058 1.00 93.77  ? 205 LEU A CD1 1 
ATOM 1478 C CD2 . LEU A 1 205 ? 139.513 182.499 170.313 1.00 93.90  ? 205 LEU A CD2 1 
ATOM 1479 N N   . GLY A 1 206 ? 136.545 187.515 168.408 1.00 97.81  ? 206 GLY A N   1 
ATOM 1480 C CA  . GLY A 1 206 ? 136.301 188.219 167.163 1.00 96.47  ? 206 GLY A CA  1 
ATOM 1481 C C   . GLY A 1 206 ? 137.509 188.993 166.682 1.00 96.50  ? 206 GLY A C   1 
ATOM 1482 O O   . GLY A 1 206 ? 137.734 189.112 165.475 1.00 100.20 ? 206 GLY A O   1 
ATOM 1483 N N   . LYS A 1 207 ? 138.311 189.518 167.610 1.00 90.37  ? 207 LYS A N   1 
ATOM 1484 C CA  . LYS A 1 207 ? 139.539 190.200 167.220 1.00 89.01  ? 207 LYS A CA  1 
ATOM 1485 C C   . LYS A 1 207 ? 140.476 189.253 166.483 1.00 89.71  ? 207 LYS A C   1 
ATOM 1486 O O   . LYS A 1 207 ? 141.027 189.600 165.433 1.00 94.39  ? 207 LYS A O   1 
ATOM 1487 C CB  . LYS A 1 207 ? 140.231 190.786 168.452 1.00 92.06  ? 207 LYS A CB  1 
ATOM 1488 C CG  . LYS A 1 207 ? 139.339 191.654 169.329 1.00 94.42  ? 207 LYS A CG  1 
ATOM 1489 C CD  . LYS A 1 207 ? 138.728 192.813 168.553 1.00 96.97  ? 207 LYS A CD  1 
ATOM 1490 C CE  . LYS A 1 207 ? 139.798 193.746 168.003 1.00 94.91  ? 207 LYS A CE  1 
ATOM 1491 N NZ  . LYS A 1 207 ? 139.215 194.987 167.422 1.00 96.08  ? 207 LYS A NZ  1 
ATOM 1492 N N   . LEU A 1 208 ? 140.667 188.046 167.017 1.00 83.06  ? 208 LEU A N   1 
ATOM 1493 C CA  . LEU A 1 208 ? 141.547 187.083 166.364 1.00 85.12  ? 208 LEU A CA  1 
ATOM 1494 C C   . LEU A 1 208 ? 140.990 186.663 165.010 1.00 84.77  ? 208 LEU A C   1 
ATOM 1495 O O   . LEU A 1 208 ? 141.737 186.518 164.035 1.00 84.17  ? 208 LEU A O   1 
ATOM 1496 C CB  . LEU A 1 208 ? 141.746 185.862 167.261 1.00 86.05  ? 208 LEU A CB  1 
ATOM 1497 C CG  . LEU A 1 208 ? 142.657 184.771 166.695 1.00 82.10  ? 208 LEU A CG  1 
ATOM 1498 C CD1 . LEU A 1 208 ? 144.032 185.325 166.364 1.00 81.15  ? 208 LEU A CD1 1 
ATOM 1499 C CD2 . LEU A 1 208 ? 142.766 183.614 167.669 1.00 88.05  ? 208 LEU A CD2 1 
ATOM 1500 N N   . ILE A 1 209 ? 139.677 186.442 164.934 1.00 86.76  ? 209 ILE A N   1 
ATOM 1501 C CA  . ILE A 1 209 ? 139.076 186.043 163.662 1.00 82.67  ? 209 ILE A CA  1 
ATOM 1502 C C   . ILE A 1 209 ? 139.289 187.129 162.616 1.00 82.07  ? 209 ILE A C   1 
ATOM 1503 O O   . ILE A 1 209 ? 139.698 186.854 161.480 1.00 85.88  ? 209 ILE A O   1 
ATOM 1504 C CB  . ILE A 1 209 ? 137.582 185.716 163.840 1.00 84.44  ? 209 ILE A CB  1 
ATOM 1505 C CG1 . ILE A 1 209 ? 137.410 184.396 164.598 1.00 85.50  ? 209 ILE A CG1 1 
ATOM 1506 C CG2 . ILE A 1 209 ? 136.886 185.654 162.487 1.00 84.01  ? 209 ILE A CG2 1 
ATOM 1507 C CD1 . ILE A 1 209 ? 136.985 184.546 166.031 1.00 84.62  ? 209 ILE A CD1 1 
ATOM 1508 N N   . LEU A 1 210 ? 139.017 188.383 162.985 1.00 82.13  ? 210 LEU A N   1 
ATOM 1509 C CA  . LEU A 1 210 ? 139.225 189.484 162.055 1.00 83.07  ? 210 LEU A CA  1 
ATOM 1510 C C   . LEU A 1 210 ? 140.688 189.582 161.654 1.00 83.30  ? 210 LEU A C   1 
ATOM 1511 O O   . LEU A 1 210 ? 141.002 189.781 160.477 1.00 88.28  ? 210 LEU A O   1 
ATOM 1512 C CB  . LEU A 1 210 ? 138.737 190.794 162.680 1.00 84.17  ? 210 LEU A CB  1 
ATOM 1513 C CG  . LEU A 1 210 ? 139.171 192.127 162.057 1.00 84.18  ? 210 LEU A CG  1 
ATOM 1514 C CD1 . LEU A 1 210 ? 138.159 193.201 162.410 1.00 87.09  ? 210 LEU A CD1 1 
ATOM 1515 C CD2 . LEU A 1 210 ? 140.554 192.569 162.522 1.00 79.90  ? 210 LEU A CD2 1 
ATOM 1516 N N   . THR A 1 211 ? 141.600 189.435 162.616 1.00 79.96  ? 211 THR A N   1 
ATOM 1517 C CA  . THR A 1 211 ? 143.018 189.546 162.305 1.00 79.89  ? 211 THR A CA  1 
ATOM 1518 C C   . THR A 1 211 ? 143.451 188.471 161.319 1.00 85.85  ? 211 THR A C   1 
ATOM 1519 O O   . THR A 1 211 ? 144.156 188.764 160.350 1.00 90.96  ? 211 THR A O   1 
ATOM 1520 C CB  . THR A 1 211 ? 143.845 189.458 163.586 1.00 80.69  ? 211 THR A CB  1 
ATOM 1521 O OG1 . THR A 1 211 ? 143.372 190.427 164.529 1.00 87.20  ? 211 THR A OG1 1 
ATOM 1522 C CG2 . THR A 1 211 ? 145.315 189.713 163.294 1.00 80.56  ? 211 THR A CG2 1 
ATOM 1523 N N   . VAL A 1 212 ? 143.027 187.225 161.535 1.00 79.59  ? 212 VAL A N   1 
ATOM 1524 C CA  . VAL A 1 212 ? 143.457 186.143 160.655 1.00 74.45  ? 212 VAL A CA  1 
ATOM 1525 C C   . VAL A 1 212 ? 142.846 186.304 159.268 1.00 74.07  ? 212 VAL A C   1 
ATOM 1526 O O   . VAL A 1 212 ? 143.535 186.150 158.251 1.00 80.57  ? 212 VAL A O   1 
ATOM 1527 C CB  . VAL A 1 212 ? 143.109 184.778 161.274 1.00 76.65  ? 212 VAL A CB  1 
ATOM 1528 C CG1 . VAL A 1 212 ? 142.912 183.725 160.191 1.00 75.95  ? 212 VAL A CG1 1 
ATOM 1529 C CG2 . VAL A 1 212 ? 144.198 184.347 162.240 1.00 80.52  ? 212 VAL A CG2 1 
ATOM 1530 N N   . TYR A 1 213 ? 141.548 186.609 159.196 1.00 66.44  ? 213 TYR A N   1 
ATOM 1531 C CA  . TYR A 1 213 ? 140.922 186.774 157.889 1.00 68.56  ? 213 TYR A CA  1 
ATOM 1532 C C   . TYR A 1 213 ? 141.539 187.939 157.129 1.00 73.97  ? 213 TYR A C   1 
ATOM 1533 O O   . TYR A 1 213 ? 141.783 187.843 155.921 1.00 77.45  ? 213 TYR A O   1 
ATOM 1534 C CB  . TYR A 1 213 ? 139.416 186.970 158.046 1.00 71.92  ? 213 TYR A CB  1 
ATOM 1535 C CG  . TYR A 1 213 ? 138.648 185.672 158.082 1.00 76.30  ? 213 TYR A CG  1 
ATOM 1536 C CD1 . TYR A 1 213 ? 138.981 184.673 158.983 1.00 79.66  ? 213 TYR A CD1 1 
ATOM 1537 C CD2 . TYR A 1 213 ? 137.599 185.440 157.206 1.00 72.31  ? 213 TYR A CD2 1 
ATOM 1538 C CE1 . TYR A 1 213 ? 138.288 183.483 159.016 1.00 75.04  ? 213 TYR A CE1 1 
ATOM 1539 C CE2 . TYR A 1 213 ? 136.900 184.253 157.233 1.00 72.66  ? 213 TYR A CE2 1 
ATOM 1540 C CZ  . TYR A 1 213 ? 137.248 183.279 158.140 1.00 72.74  ? 213 TYR A CZ  1 
ATOM 1541 O OH  . TYR A 1 213 ? 136.556 182.092 158.172 1.00 81.03  ? 213 TYR A OH  1 
ATOM 1542 N N   . LEU A 1 214 ? 141.806 189.049 157.819 1.00 72.67  ? 214 LEU A N   1 
ATOM 1543 C CA  . LEU A 1 214 ? 142.390 190.205 157.156 1.00 69.51  ? 214 LEU A CA  1 
ATOM 1544 C C   . LEU A 1 214 ? 143.828 189.927 156.743 1.00 67.82  ? 214 LEU A C   1 
ATOM 1545 O O   . LEU A 1 214 ? 144.273 190.382 155.688 1.00 76.66  ? 214 LEU A O   1 
ATOM 1546 C CB  . LEU A 1 214 ? 142.290 191.424 158.075 1.00 74.39  ? 214 LEU A CB  1 
ATOM 1547 C CG  . LEU A 1 214 ? 143.185 192.642 157.855 1.00 73.94  ? 214 LEU A CG  1 
ATOM 1548 C CD1 . LEU A 1 214 ? 142.576 193.573 156.827 1.00 74.99  ? 214 LEU A CD1 1 
ATOM 1549 C CD2 . LEU A 1 214 ? 143.354 193.369 159.172 1.00 75.72  ? 214 LEU A CD2 1 
ATOM 1550 N N   . GLY A 1 215 ? 144.570 189.168 157.549 1.00 64.81  ? 215 GLY A N   1 
ATOM 1551 C CA  . GLY A 1 215 ? 145.906 188.774 157.140 1.00 64.94  ? 215 GLY A CA  1 
ATOM 1552 C C   . GLY A 1 215 ? 145.891 187.924 155.886 1.00 69.24  ? 215 GLY A C   1 
ATOM 1553 O O   . GLY A 1 215 ? 146.695 188.130 154.974 1.00 68.58  ? 215 GLY A O   1 
ATOM 1554 N N   . CYS A 1 216 ? 144.966 186.966 155.815 1.00 80.18  ? 216 CYS A N   1 
ATOM 1555 C CA  . CYS A 1 216 ? 144.850 186.134 154.621 1.00 78.02  ? 216 CYS A CA  1 
ATOM 1556 C C   . CYS A 1 216 ? 144.466 186.969 153.404 1.00 77.18  ? 216 CYS A C   1 
ATOM 1557 O O   . CYS A 1 216 ? 145.028 186.801 152.314 1.00 77.12  ? 216 CYS A O   1 
ATOM 1558 C CB  . CYS A 1 216 ? 143.825 185.028 154.863 1.00 78.79  ? 216 CYS A CB  1 
ATOM 1559 S SG  . CYS A 1 216 ? 144.381 183.748 156.011 1.00 87.05  ? 216 CYS A SG  1 
ATOM 1560 N N   . ILE A 1 217 ? 143.503 187.877 153.572 1.00 75.34  ? 217 ILE A N   1 
ATOM 1561 C CA  . ILE A 1 217 ? 143.069 188.714 152.458 1.00 73.41  ? 217 ILE A CA  1 
ATOM 1562 C C   . ILE A 1 217 ? 144.209 189.605 151.985 1.00 74.63  ? 217 ILE A C   1 
ATOM 1563 O O   . ILE A 1 217 ? 144.418 189.781 150.780 1.00 75.31  ? 217 ILE A O   1 
ATOM 1564 C CB  . ILE A 1 217 ? 141.837 189.543 152.865 1.00 72.83  ? 217 ILE A CB  1 
ATOM 1565 C CG1 . ILE A 1 217 ? 140.608 188.641 153.010 1.00 74.09  ? 217 ILE A CG1 1 
ATOM 1566 C CG2 . ILE A 1 217 ? 141.580 190.646 151.851 1.00 73.33  ? 217 ILE A CG2 1 
ATOM 1567 C CD1 . ILE A 1 217 ? 140.097 188.057 151.704 1.00 76.44  ? 217 ILE A CD1 1 
ATOM 1568 N N   . ILE A 1 218 ? 144.954 190.192 152.922 1.00 74.64  ? 218 ILE A N   1 
ATOM 1569 C CA  . ILE A 1 218 ? 146.097 191.021 152.556 1.00 70.08  ? 218 ILE A CA  1 
ATOM 1570 C C   . ILE A 1 218 ? 147.145 190.193 151.830 1.00 67.91  ? 218 ILE A C   1 
ATOM 1571 O O   . ILE A 1 218 ? 147.740 190.648 150.851 1.00 73.28  ? 218 ILE A O   1 
ATOM 1572 C CB  . ILE A 1 218 ? 146.677 191.718 153.802 1.00 68.29  ? 218 ILE A CB  1 
ATOM 1573 C CG1 . ILE A 1 218 ? 145.932 193.026 154.090 1.00 68.86  ? 218 ILE A CG1 1 
ATOM 1574 C CG2 . ILE A 1 218 ? 148.162 192.001 153.626 1.00 65.88  ? 218 ILE A CG2 1 
ATOM 1575 C CD1 . ILE A 1 218 ? 144.428 192.964 153.925 1.00 69.30  ? 218 ILE A CD1 1 
ATOM 1576 N N   . HIS A 1 219 ? 147.400 188.970 152.296 1.00 61.95  ? 219 HIS A N   1 
ATOM 1577 C CA  . HIS A 1 219 ? 148.338 188.116 151.578 1.00 64.02  ? 219 HIS A CA  1 
ATOM 1578 C C   . HIS A 1 219 ? 147.885 187.907 150.141 1.00 65.25  ? 219 HIS A C   1 
ATOM 1579 O O   . HIS A 1 219 ? 148.664 188.101 149.200 1.00 71.05  ? 219 HIS A O   1 
ATOM 1580 C CB  . HIS A 1 219 ? 148.485 186.775 152.292 1.00 58.83  ? 219 HIS A CB  1 
ATOM 1581 C CG  . HIS A 1 219 ? 149.664 185.975 151.832 1.00 60.68  ? 219 HIS A CG  1 
ATOM 1582 N ND1 . HIS A 1 219 ? 150.964 186.363 152.068 1.00 63.33  ? 219 HIS A ND1 1 
ATOM 1583 C CD2 . HIS A 1 219 ? 149.738 184.808 151.151 1.00 67.21  ? 219 HIS A CD2 1 
ATOM 1584 C CE1 . HIS A 1 219 ? 151.789 185.471 151.551 1.00 65.81  ? 219 HIS A CE1 1 
ATOM 1585 N NE2 . HIS A 1 219 ? 151.070 184.516 150.990 1.00 66.05  ? 219 HIS A NE2 1 
ATOM 1586 N N   . ILE A 1 220 ? 146.614 187.555 149.952 1.00 65.58  ? 220 ILE A N   1 
ATOM 1587 C CA  . ILE A 1 220 ? 146.108 187.279 148.610 1.00 64.92  ? 220 ILE A CA  1 
ATOM 1588 C C   . ILE A 1 220 ? 146.193 188.525 147.735 1.00 66.37  ? 220 ILE A C   1 
ATOM 1589 O O   . ILE A 1 220 ? 146.497 188.442 146.540 1.00 72.10  ? 220 ILE A O   1 
ATOM 1590 C CB  . ILE A 1 220 ? 144.669 186.739 148.683 1.00 63.26  ? 220 ILE A CB  1 
ATOM 1591 C CG1 . ILE A 1 220 ? 144.664 185.349 149.323 1.00 62.45  ? 220 ILE A CG1 1 
ATOM 1592 C CG2 . ILE A 1 220 ? 144.043 186.705 147.296 1.00 65.61  ? 220 ILE A CG2 1 
ATOM 1593 C CD1 . ILE A 1 220 ? 143.283 184.787 149.565 1.00 70.35  ? 220 ILE A CD1 1 
ATOM 1594 N N   . LEU A 1 221 ? 145.920 189.698 148.312 1.00 70.88  ? 221 LEU A N   1 
ATOM 1595 C CA  . LEU A 1 221 ? 145.792 190.907 147.505 1.00 65.71  ? 221 LEU A CA  1 
ATOM 1596 C C   . LEU A 1 221 ? 147.114 191.637 147.302 1.00 62.90  ? 221 LEU A C   1 
ATOM 1597 O O   . LEU A 1 221 ? 147.213 192.473 146.398 1.00 63.26  ? 221 LEU A O   1 
ATOM 1598 C CB  . LEU A 1 221 ? 144.781 191.856 148.149 1.00 70.21  ? 221 LEU A CB  1 
ATOM 1599 C CG  . LEU A 1 221 ? 143.340 191.745 147.650 1.00 73.34  ? 221 LEU A CG  1 
ATOM 1600 C CD1 . LEU A 1 221 ? 142.872 190.298 147.640 1.00 70.47  ? 221 LEU A CD1 1 
ATOM 1601 C CD2 . LEU A 1 221 ? 142.415 192.597 148.503 1.00 70.00  ? 221 LEU A CD2 1 
ATOM 1602 N N   . ILE A 1 222 ? 148.127 191.359 148.118 1.00 65.96  ? 222 ILE A N   1 
ATOM 1603 C CA  . ILE A 1 222 ? 149.389 192.082 148.057 1.00 68.47  ? 222 ILE A CA  1 
ATOM 1604 C C   . ILE A 1 222 ? 150.521 191.199 147.551 1.00 71.28  ? 222 ILE A C   1 
ATOM 1605 O O   . ILE A 1 222 ? 151.369 191.659 146.789 1.00 78.07  ? 222 ILE A O   1 
ATOM 1606 C CB  . ILE A 1 222 ? 149.728 192.681 149.441 1.00 73.48  ? 222 ILE A CB  1 
ATOM 1607 C CG1 . ILE A 1 222 ? 149.132 194.084 149.587 1.00 75.36  ? 222 ILE A CG1 1 
ATOM 1608 C CG2 . ILE A 1 222 ? 151.235 192.748 149.662 1.00 70.44  ? 222 ILE A CG2 1 
ATOM 1609 C CD1 . ILE A 1 222 ? 147.701 194.207 149.115 1.00 66.74  ? 222 ILE A CD1 1 
ATOM 1610 N N   . VAL A 1 223 ? 150.572 189.938 147.975 1.00 60.96  ? 223 VAL A N   1 
ATOM 1611 C CA  . VAL A 1 223 ? 151.670 189.064 147.582 1.00 61.30  ? 223 VAL A CA  1 
ATOM 1612 C C   . VAL A 1 223 ? 151.297 188.350 146.291 1.00 67.05  ? 223 VAL A C   1 
ATOM 1613 O O   . VAL A 1 223 ? 152.014 188.442 145.289 1.00 73.91  ? 223 VAL A O   1 
ATOM 1614 C CB  . VAL A 1 223 ? 152.015 188.058 148.694 1.00 62.33  ? 223 VAL A CB  1 
ATOM 1615 C CG1 . VAL A 1 223 ? 153.178 187.179 148.271 1.00 63.91  ? 223 VAL A CG1 1 
ATOM 1616 C CG2 . VAL A 1 223 ? 152.346 188.787 149.987 1.00 65.81  ? 223 VAL A CG2 1 
ATOM 1617 N N   . TYR A 1 224 ? 150.170 187.638 146.300 1.00 68.99  ? 224 TYR A N   1 
ATOM 1618 C CA  . TYR A 1 224 ? 149.771 186.883 145.118 1.00 65.70  ? 224 TYR A CA  1 
ATOM 1619 C C   . TYR A 1 224 ? 149.408 187.813 143.967 1.00 63.94  ? 224 TYR A C   1 
ATOM 1620 O O   . TYR A 1 224 ? 149.854 187.616 142.831 1.00 72.23  ? 224 TYR A O   1 
ATOM 1621 C CB  . TYR A 1 224 ? 148.597 185.963 145.458 1.00 63.55  ? 224 TYR A CB  1 
ATOM 1622 C CG  . TYR A 1 224 ? 148.932 184.848 146.429 1.00 61.81  ? 224 TYR A CG  1 
ATOM 1623 C CD1 . TYR A 1 224 ? 150.247 184.466 146.662 1.00 58.04  ? 224 TYR A CD1 1 
ATOM 1624 C CD2 . TYR A 1 224 ? 147.929 184.174 147.108 1.00 63.94  ? 224 TYR A CD2 1 
ATOM 1625 C CE1 . TYR A 1 224 ? 150.550 183.452 147.544 1.00 59.52  ? 224 TYR A CE1 1 
ATOM 1626 C CE2 . TYR A 1 224 ? 148.224 183.157 147.992 1.00 65.82  ? 224 TYR A CE2 1 
ATOM 1627 C CZ  . TYR A 1 224 ? 149.536 182.802 148.207 1.00 66.71  ? 224 TYR A CZ  1 
ATOM 1628 O OH  . TYR A 1 224 ? 149.837 181.789 149.086 1.00 71.50  ? 224 TYR A OH  1 
ATOM 1629 N N   . THR A 1 225 ? 148.601 188.839 144.242 1.00 69.87  ? 225 THR A N   1 
ATOM 1630 C CA  . THR A 1 225 ? 148.126 189.703 143.167 1.00 70.77  ? 225 THR A CA  1 
ATOM 1631 C C   . THR A 1 225 ? 149.273 190.467 142.519 1.00 74.40  ? 225 THR A C   1 
ATOM 1632 O O   . THR A 1 225 ? 149.378 190.513 141.288 1.00 80.76  ? 225 THR A O   1 
ATOM 1633 C CB  . THR A 1 225 ? 147.075 190.676 143.699 1.00 75.15  ? 225 THR A CB  1 
ATOM 1634 O OG1 . THR A 1 225 ? 145.968 189.942 144.235 1.00 82.26  ? 225 THR A OG1 1 
ATOM 1635 C CG2 . THR A 1 225 ? 146.583 191.587 142.589 1.00 68.63  ? 225 THR A CG2 1 
ATOM 1636 N N   . LEU A 1 226 ? 150.141 191.076 143.326 1.00 73.74  ? 226 LEU A N   1 
ATOM 1637 C CA  . LEU A 1 226 ? 151.251 191.835 142.760 1.00 72.04  ? 226 LEU A CA  1 
ATOM 1638 C C   . LEU A 1 226 ? 152.209 190.926 142.005 1.00 73.28  ? 226 LEU A C   1 
ATOM 1639 O O   . LEU A 1 226 ? 152.735 191.309 140.954 1.00 81.35  ? 226 LEU A O   1 
ATOM 1640 C CB  . LEU A 1 226 ? 151.989 192.595 143.859 1.00 66.96  ? 226 LEU A CB  1 
ATOM 1641 C CG  . LEU A 1 226 ? 151.443 193.991 144.163 1.00 73.37  ? 226 LEU A CG  1 
ATOM 1642 C CD1 . LEU A 1 226 ? 149.968 193.930 144.516 1.00 75.24  ? 226 LEU A CD1 1 
ATOM 1643 C CD2 . LEU A 1 226 ? 152.233 194.633 145.288 1.00 76.77  ? 226 LEU A CD2 1 
ATOM 1644 N N   . LEU A 1 227 ? 152.464 189.727 142.529 1.00 71.14  ? 227 LEU A N   1 
ATOM 1645 C CA  . LEU A 1 227 ? 153.299 188.774 141.809 1.00 69.25  ? 227 LEU A CA  1 
ATOM 1646 C C   . LEU A 1 227 ? 152.696 188.460 140.446 1.00 67.68  ? 227 LEU A C   1 
ATOM 1647 O O   . LEU A 1 227 ? 153.361 188.581 139.414 1.00 75.86  ? 227 LEU A O   1 
ATOM 1648 C CB  . LEU A 1 227 ? 153.472 187.497 142.633 1.00 68.91  ? 227 LEU A CB  1 
ATOM 1649 C CG  . LEU A 1 227 ? 154.443 187.587 143.811 1.00 70.10  ? 227 LEU A CG  1 
ATOM 1650 C CD1 . LEU A 1 227 ? 154.244 186.415 144.756 1.00 71.95  ? 227 LEU A CD1 1 
ATOM 1651 C CD2 . LEU A 1 227 ? 155.879 187.639 143.325 1.00 63.25  ? 227 LEU A CD2 1 
ATOM 1652 N N   . LEU A 1 228 ? 151.417 188.086 140.422 1.00 69.74  ? 228 LEU A N   1 
ATOM 1653 C CA  . LEU A 1 228 ? 150.772 187.777 139.151 1.00 71.64  ? 228 LEU A CA  1 
ATOM 1654 C C   . LEU A 1 228 ? 150.834 188.963 138.200 1.00 73.89  ? 228 LEU A C   1 
ATOM 1655 O O   . LEU A 1 228 ? 150.989 188.791 136.986 1.00 80.43  ? 228 LEU A O   1 
ATOM 1656 C CB  . LEU A 1 228 ? 149.320 187.362 139.384 1.00 76.97  ? 228 LEU A CB  1 
ATOM 1657 C CG  . LEU A 1 228 ? 149.105 186.082 140.191 1.00 81.78  ? 228 LEU A CG  1 
ATOM 1658 C CD1 . LEU A 1 228 ? 147.659 185.989 140.645 1.00 80.62  ? 228 LEU A CD1 1 
ATOM 1659 C CD2 . LEU A 1 228 ? 149.493 184.861 139.381 1.00 78.11  ? 228 LEU A CD2 1 
ATOM 1660 N N   . ARG A 1 229 ? 150.713 190.178 138.733 1.00 81.18  ? 229 ARG A N   1 
ATOM 1661 C CA  . ARG A 1 229 ? 150.674 191.358 137.877 1.00 83.89  ? 229 ARG A CA  1 
ATOM 1662 C C   . ARG A 1 229 ? 152.045 191.672 137.290 1.00 88.00  ? 229 ARG A C   1 
ATOM 1663 O O   . ARG A 1 229 ? 152.156 192.034 136.114 1.00 87.86  ? 229 ARG A O   1 
ATOM 1664 C CB  . ARG A 1 229 ? 150.141 192.554 138.668 1.00 84.10  ? 229 ARG A CB  1 
ATOM 1665 C CG  . ARG A 1 229 ? 150.059 193.852 137.877 1.00 86.06  ? 229 ARG A CG  1 
ATOM 1666 C CD  . ARG A 1 229 ? 149.218 193.714 136.620 1.00 88.06  ? 229 ARG A CD  1 
ATOM 1667 N NE  . ARG A 1 229 ? 149.171 194.961 135.866 1.00 94.47  ? 229 ARG A NE  1 
ATOM 1668 C CZ  . ARG A 1 229 ? 150.179 195.442 135.150 1.00 92.50  ? 229 ARG A CZ  1 
ATOM 1669 N NH1 . ARG A 1 229 ? 151.335 194.803 135.067 1.00 89.95  ? 229 ARG A NH1 1 
ATOM 1670 N NH2 . ARG A 1 229 ? 150.024 196.592 134.502 1.00 88.99  ? 229 ARG A NH2 1 
ATOM 1671 N N   . PHE A 1 230 ? 153.102 191.538 138.090 1.00 83.38  ? 230 PHE A N   1 
ATOM 1672 C CA  . PHE A 1 230 ? 154.407 192.064 137.709 1.00 76.64  ? 230 PHE A CA  1 
ATOM 1673 C C   . PHE A 1 230 ? 155.378 191.011 137.198 1.00 80.00  ? 230 PHE A C   1 
ATOM 1674 O O   . PHE A 1 230 ? 156.165 191.310 136.294 1.00 87.61  ? 230 PHE A O   1 
ATOM 1675 C CB  . PHE A 1 230 ? 155.048 192.792 138.897 1.00 75.42  ? 230 PHE A CB  1 
ATOM 1676 C CG  . PHE A 1 230 ? 154.573 194.211 139.076 1.00 83.53  ? 230 PHE A CG  1 
ATOM 1677 C CD1 . PHE A 1 230 ? 154.416 195.055 137.987 1.00 85.01  ? 230 PHE A CD1 1 
ATOM 1678 C CD2 . PHE A 1 230 ? 154.285 194.699 140.338 1.00 81.53  ? 230 PHE A CD2 1 
ATOM 1679 C CE1 . PHE A 1 230 ? 153.981 196.353 138.155 1.00 83.01  ? 230 PHE A CE1 1 
ATOM 1680 C CE2 . PHE A 1 230 ? 153.849 195.997 140.511 1.00 83.44  ? 230 PHE A CE2 1 
ATOM 1681 C CZ  . PHE A 1 230 ? 153.697 196.824 139.418 1.00 86.01  ? 230 PHE A CZ  1 
ATOM 1682 N N   . LEU A 1 231 ? 155.365 189.795 137.740 1.00 76.87  ? 231 LEU A N   1 
ATOM 1683 C CA  . LEU A 1 231 ? 156.274 188.750 137.293 1.00 74.47  ? 231 LEU A CA  1 
ATOM 1684 C C   . LEU A 1 231 ? 155.647 187.861 136.226 1.00 82.33  ? 231 LEU A C   1 
ATOM 1685 O O   . LEU A 1 231 ? 156.297 187.541 135.227 1.00 88.15  ? 231 LEU A O   1 
ATOM 1686 C CB  . LEU A 1 231 ? 156.720 187.906 138.491 1.00 77.84  ? 231 LEU A CB  1 
ATOM 1687 C CG  . LEU A 1 231 ? 157.681 186.764 138.166 1.00 82.43  ? 231 LEU A CG  1 
ATOM 1688 C CD1 . LEU A 1 231 ? 158.810 186.719 139.181 1.00 80.41  ? 231 LEU A CD1 1 
ATOM 1689 C CD2 . LEU A 1 231 ? 156.945 185.441 138.127 1.00 79.95  ? 231 LEU A CD2 1 
ATOM 1690 N N   . CYS A 1 232 ? 154.391 187.449 136.420 1.00 91.67  ? 232 CYS A N   1 
ATOM 1691 C CA  . CYS A 1 232 ? 153.690 186.680 135.398 1.00 90.82  ? 232 CYS A CA  1 
ATOM 1692 C C   . CYS A 1 232 ? 153.190 187.560 134.261 1.00 87.66  ? 232 CYS A C   1 
ATOM 1693 O O   . CYS A 1 232 ? 152.978 187.066 133.150 1.00 85.42  ? 232 CYS A O   1 
ATOM 1694 C CB  . CYS A 1 232 ? 152.515 185.925 136.017 1.00 88.00  ? 232 CYS A CB  1 
ATOM 1695 S SG  . CYS A 1 232 ? 152.949 184.889 137.417 1.00 100.75 ? 232 CYS A SG  1 
ATOM 1696 N N   . LYS A 1 233 ? 152.992 188.852 134.514 1.00 82.69  ? 233 LYS A N   1 
ATOM 1697 C CA  . LYS A 1 233 ? 152.500 189.817 133.536 1.00 85.98  ? 233 LYS A CA  1 
ATOM 1698 C C   . LYS A 1 233 ? 151.070 189.531 133.100 1.00 91.29  ? 233 LYS A C   1 
ATOM 1699 O O   . LYS A 1 233 ? 150.625 190.063 132.075 1.00 95.10  ? 233 LYS A O   1 
ATOM 1700 C CB  . LYS A 1 233 ? 153.404 189.878 132.296 1.00 87.90  ? 233 LYS A CB  1 
ATOM 1701 C CG  . LYS A 1 233 ? 154.266 191.140 132.203 1.00 86.78  ? 233 LYS A CG  1 
ATOM 1702 C CD  . LYS A 1 233 ? 155.502 191.117 133.109 1.00 88.10  ? 233 LYS A CD  1 
ATOM 1703 C CE  . LYS A 1 233 ? 156.291 189.808 133.055 1.00 86.28  ? 233 LYS A CE  1 
ATOM 1704 N NZ  . LYS A 1 233 ? 157.566 189.901 133.814 1.00 88.56  ? 233 LYS A NZ  1 
ATOM 1705 N N   . ILE A 1 234 ? 150.328 188.727 133.855 1.00 95.21  ? 234 ILE A N   1 
ATOM 1706 C CA  . ILE A 1 234 ? 148.958 188.384 133.506 1.00 94.27  ? 234 ILE A CA  1 
ATOM 1707 C C   . ILE A 1 234 ? 148.017 189.040 134.508 1.00 93.86  ? 234 ILE A C   1 
ATOM 1708 O O   . ILE A 1 234 ? 148.376 189.324 135.655 1.00 97.96  ? 234 ILE A O   1 
ATOM 1709 C CB  . ILE A 1 234 ? 148.723 186.853 133.449 1.00 93.49  ? 234 ILE A CB  1 
ATOM 1710 C CG1 . ILE A 1 234 ? 149.315 186.153 134.677 1.00 91.57  ? 234 ILE A CG1 1 
ATOM 1711 C CG2 . ILE A 1 234 ? 149.300 186.283 132.162 1.00 92.77  ? 234 ILE A CG2 1 
ATOM 1712 C CD1 . ILE A 1 234 ? 149.386 184.638 134.560 1.00 89.56  ? 234 ILE A CD1 1 
ATOM 1713 N N   . ASN A 1 235 ? 146.790 189.284 134.065 1.00 86.50  ? 235 ASN A N   1 
ATOM 1714 C CA  . ASN A 1 235 ? 145.804 189.932 134.916 1.00 87.45  ? 235 ASN A CA  1 
ATOM 1715 C C   . ASN A 1 235 ? 145.466 189.035 136.103 1.00 88.13  ? 235 ASN A C   1 
ATOM 1716 O O   . ASN A 1 235 ? 145.347 187.814 135.936 1.00 88.65  ? 235 ASN A O   1 
ATOM 1717 C CB  . ASN A 1 235 ? 144.538 190.238 134.121 1.00 84.81  ? 235 ASN A CB  1 
ATOM 1718 C CG  . ASN A 1 235 ? 143.520 191.024 134.920 1.00 89.68  ? 235 ASN A CG  1 
ATOM 1719 O OD1 . ASN A 1 235 ? 143.099 190.602 135.995 1.00 92.99  ? 235 ASN A OD1 1 
ATOM 1720 N ND2 . ASN A 1 235 ? 143.106 192.168 134.390 1.00 89.79  ? 235 ASN A ND2 1 
ATOM 1721 N N   . PRO A 1 236 ? 145.300 189.590 137.308 1.00 81.17  ? 236 PRO A N   1 
ATOM 1722 C CA  . PRO A 1 236 ? 144.911 188.757 138.452 1.00 81.60  ? 236 PRO A CA  1 
ATOM 1723 C C   . PRO A 1 236 ? 143.412 188.515 138.514 1.00 85.70  ? 236 PRO A C   1 
ATOM 1724 O O   . PRO A 1 236 ? 142.959 187.495 139.046 1.00 90.71  ? 236 PRO A O   1 
ATOM 1725 C CB  . PRO A 1 236 ? 145.393 189.576 139.652 1.00 81.77  ? 236 PRO A CB  1 
ATOM 1726 C CG  . PRO A 1 236 ? 145.280 190.986 139.192 1.00 83.85  ? 236 PRO A CG  1 
ATOM 1727 C CD  . PRO A 1 236 ? 145.544 190.988 137.708 1.00 81.35  ? 236 PRO A CD  1 
ATOM 1728 N N   . LEU A 1 237 ? 142.630 189.452 137.976 1.00 88.26  ? 237 LEU A N   1 
ATOM 1729 C CA  . LEU A 1 237 ? 141.179 189.346 138.078 1.00 86.49  ? 237 LEU A CA  1 
ATOM 1730 C C   . LEU A 1 237 ? 140.671 188.104 137.354 1.00 88.71  ? 237 LEU A C   1 
ATOM 1731 O O   . LEU A 1 237 ? 139.912 187.312 137.921 1.00 86.15  ? 237 LEU A O   1 
ATOM 1732 C CB  . LEU A 1 237 ? 140.522 190.616 137.531 1.00 89.61  ? 237 LEU A CB  1 
ATOM 1733 C CG  . LEU A 1 237 ? 139.020 190.817 137.768 1.00 87.10  ? 237 LEU A CG  1 
ATOM 1734 C CD1 . LEU A 1 237 ? 138.182 189.892 136.897 1.00 86.40  ? 237 LEU A CD1 1 
ATOM 1735 C CD2 . LEU A 1 237 ? 138.670 190.627 139.240 1.00 85.43  ? 237 LEU A CD2 1 
ATOM 1736 N N   . ARG A 1 238 ? 141.086 187.910 136.098 1.00 91.02  ? 238 ARG A N   1 
ATOM 1737 C CA  . ARG A 1 238 ? 140.683 186.700 135.383 1.00 87.83  ? 238 ARG A CA  1 
ATOM 1738 C C   . ARG A 1 238 ? 141.284 185.457 136.023 1.00 88.75  ? 238 ARG A C   1 
ATOM 1739 O O   . ARG A 1 238 ? 140.661 184.392 136.023 1.00 88.18  ? 238 ARG A O   1 
ATOM 1740 C CB  . ARG A 1 238 ? 141.065 186.771 133.901 1.00 89.62  ? 238 ARG A CB  1 
ATOM 1741 C CG  . ARG A 1 238 ? 140.834 188.110 133.209 1.00 90.26  ? 238 ARG A CG  1 
ATOM 1742 C CD  . ARG A 1 238 ? 141.900 188.409 132.161 1.00 93.10  ? 238 ARG A CD  1 
ATOM 1743 N NE  . ARG A 1 238 ? 142.177 187.278 131.279 1.00 96.79  ? 238 ARG A NE  1 
ATOM 1744 C CZ  . ARG A 1 238 ? 143.204 186.446 131.409 1.00 94.76  ? 238 ARG A CZ  1 
ATOM 1745 N NH1 . ARG A 1 238 ? 144.074 186.563 132.398 1.00 95.24  ? 238 ARG A NH1 1 
ATOM 1746 N NH2 . ARG A 1 238 ? 143.364 185.471 130.518 1.00 89.36  ? 238 ARG A NH2 1 
ATOM 1747 N N   . PHE A 1 239 ? 142.497 185.563 136.566 1.00 80.86  ? 239 PHE A N   1 
ATOM 1748 C CA  . PHE A 1 239 ? 143.090 184.421 137.255 1.00 77.79  ? 239 PHE A CA  1 
ATOM 1749 C C   . PHE A 1 239 ? 142.174 183.928 138.370 1.00 77.60  ? 239 PHE A C   1 
ATOM 1750 O O   . PHE A 1 239 ? 141.820 182.742 138.428 1.00 79.37  ? 239 PHE A O   1 
ATOM 1751 C CB  . PHE A 1 239 ? 144.461 184.812 137.808 1.00 76.03  ? 239 PHE A CB  1 
ATOM 1752 C CG  . PHE A 1 239 ? 145.263 183.654 138.326 1.00 83.31  ? 239 PHE A CG  1 
ATOM 1753 C CD1 . PHE A 1 239 ? 145.215 183.308 139.664 1.00 80.65  ? 239 PHE A CD1 1 
ATOM 1754 C CD2 . PHE A 1 239 ? 146.070 182.917 137.477 1.00 80.92  ? 239 PHE A CD2 1 
ATOM 1755 C CE1 . PHE A 1 239 ? 145.953 182.245 140.145 1.00 77.57  ? 239 PHE A CE1 1 
ATOM 1756 C CE2 . PHE A 1 239 ? 146.810 181.853 137.953 1.00 72.74  ? 239 PHE A CE2 1 
ATOM 1757 C CZ  . PHE A 1 239 ? 146.751 181.517 139.288 1.00 75.80  ? 239 PHE A CZ  1 
ATOM 1758 N N   . PHE A 1 240 ? 141.760 184.837 139.256 1.00 79.86  ? 240 PHE A N   1 
ATOM 1759 C CA  . PHE A 1 240 ? 140.853 184.454 140.332 1.00 76.86  ? 240 PHE A CA  1 
ATOM 1760 C C   . PHE A 1 240 ? 139.504 184.010 139.784 1.00 81.69  ? 240 PHE A C   1 
ATOM 1761 O O   . PHE A 1 240 ? 138.918 183.038 140.276 1.00 89.09  ? 240 PHE A O   1 
ATOM 1762 C CB  . PHE A 1 240 ? 140.681 185.612 141.314 1.00 76.77  ? 240 PHE A CB  1 
ATOM 1763 C CG  . PHE A 1 240 ? 141.941 185.982 142.043 1.00 78.98  ? 240 PHE A CG  1 
ATOM 1764 C CD1 . PHE A 1 240 ? 142.668 185.023 142.727 1.00 80.49  ? 240 PHE A CD1 1 
ATOM 1765 C CD2 . PHE A 1 240 ? 142.394 187.289 142.052 1.00 76.07  ? 240 PHE A CD2 1 
ATOM 1766 C CE1 . PHE A 1 240 ? 143.826 185.360 143.399 1.00 79.78  ? 240 PHE A CE1 1 
ATOM 1767 C CE2 . PHE A 1 240 ? 143.550 187.631 142.724 1.00 75.97  ? 240 PHE A CE2 1 
ATOM 1768 C CZ  . PHE A 1 240 ? 144.267 186.665 143.397 1.00 78.37  ? 240 PHE A CZ  1 
ATOM 1769 N N   . LYS A 1 241 ? 138.990 184.706 138.769 1.00 81.47  ? 241 LYS A N   1 
ATOM 1770 C CA  . LYS A 1 241 ? 137.710 184.327 138.187 1.00 81.90  ? 241 LYS A CA  1 
ATOM 1771 C C   . LYS A 1 241 ? 137.753 182.923 137.602 1.00 83.46  ? 241 LYS A C   1 
ATOM 1772 O O   . LYS A 1 241 ? 136.707 182.277 137.488 1.00 89.15  ? 241 LYS A O   1 
ATOM 1773 C CB  . LYS A 1 241 ? 137.313 185.354 137.120 1.00 82.40  ? 241 LYS A CB  1 
ATOM 1774 C CG  . LYS A 1 241 ? 136.315 184.881 136.064 1.00 84.21  ? 241 LYS A CG  1 
ATOM 1775 C CD  . LYS A 1 241 ? 134.911 184.777 136.632 1.00 86.65  ? 241 LYS A CD  1 
ATOM 1776 C CE  . LYS A 1 241 ? 133.860 185.038 135.565 1.00 86.12  ? 241 LYS A CE  1 
ATOM 1777 N NZ  . LYS A 1 241 ? 133.669 186.493 135.313 1.00 83.14  ? 241 LYS A NZ  1 
ATOM 1778 N N   . LYS A 1 242 ? 138.936 182.445 137.219 1.00 82.80  ? 242 LYS A N   1 
ATOM 1779 C CA  . LYS A 1 242 ? 139.060 181.088 136.700 1.00 82.45  ? 242 LYS A CA  1 
ATOM 1780 C C   . LYS A 1 242 ? 139.215 180.078 137.830 1.00 81.87  ? 242 LYS A C   1 
ATOM 1781 O O   . LYS A 1 242 ? 138.641 178.985 137.782 1.00 83.85  ? 242 LYS A O   1 
ATOM 1782 C CB  . LYS A 1 242 ? 140.246 180.998 135.736 1.00 84.58  ? 242 LYS A CB  1 
ATOM 1783 C CG  . LYS A 1 242 ? 140.181 181.973 134.572 1.00 86.87  ? 242 LYS A CG  1 
ATOM 1784 C CD  . LYS A 1 242 ? 140.163 181.255 133.232 1.00 83.00  ? 242 LYS A CD  1 
ATOM 1785 C CE  . LYS A 1 242 ? 140.524 182.190 132.084 1.00 89.56  ? 242 LYS A CE  1 
ATOM 1786 N NZ  . LYS A 1 242 ? 141.839 182.866 132.274 1.00 89.62  ? 242 LYS A NZ  1 
ATOM 1787 N N   . ILE A 1 243 ? 139.984 180.426 138.862 1.00 73.03  ? 243 ILE A N   1 
ATOM 1788 C CA  . ILE A 1 243 ? 140.261 179.464 139.928 1.00 68.63  ? 243 ILE A CA  1 
ATOM 1789 C C   . ILE A 1 243 ? 139.237 179.591 141.050 1.00 75.42  ? 243 ILE A C   1 
ATOM 1790 O O   . ILE A 1 243 ? 139.442 179.061 142.147 1.00 82.25  ? 243 ILE A O   1 
ATOM 1791 C CB  . ILE A 1 243 ? 141.689 179.625 140.479 1.00 69.19  ? 243 ILE A CB  1 
ATOM 1792 C CG1 . ILE A 1 243 ? 141.884 180.998 141.128 1.00 71.81  ? 243 ILE A CG1 1 
ATOM 1793 C CG2 . ILE A 1 243 ? 142.704 179.420 139.368 1.00 76.69  ? 243 ILE A CG2 1 
ATOM 1794 C CD1 . ILE A 1 243 ? 143.122 181.085 141.989 1.00 71.24  ? 243 ILE A CD1 1 
ATOM 1795 N N   . LYS A 1 244 ? 138.132 180.292 140.790 1.00 77.34  ? 244 LYS A N   1 
ATOM 1796 C CA  . LYS A 1 244 ? 137.121 180.507 141.822 1.00 73.75  ? 244 LYS A CA  1 
ATOM 1797 C C   . LYS A 1 244 ? 136.656 179.190 142.437 1.00 70.69  ? 244 LYS A C   1 
ATOM 1798 O O   . LYS A 1 244 ? 136.499 179.081 143.657 1.00 73.78  ? 244 LYS A O   1 
ATOM 1799 C CB  . LYS A 1 244 ? 135.927 181.273 141.244 1.00 73.61  ? 244 LYS A CB  1 
ATOM 1800 C CG  . LYS A 1 244 ? 135.410 180.758 139.908 1.00 75.19  ? 244 LYS A CG  1 
ATOM 1801 C CD  . LYS A 1 244 ? 134.468 181.761 139.263 1.00 76.66  ? 244 LYS A CD  1 
ATOM 1802 C CE  . LYS A 1 244 ? 133.875 181.229 137.967 1.00 79.33  ? 244 LYS A CE  1 
ATOM 1803 N NZ  . LYS A 1 244 ? 134.790 180.299 137.250 1.00 74.79  ? 244 LYS A NZ  1 
ATOM 1804 N N   . GLU A 1 245 ? 136.420 178.176 141.602 1.00 68.21  ? 245 GLU A N   1 
ATOM 1805 C CA  . GLU A 1 245 ? 135.906 176.906 142.109 1.00 67.55  ? 245 GLU A CA  1 
ATOM 1806 C C   . GLU A 1 245 ? 136.858 176.293 143.129 1.00 69.48  ? 245 GLU A C   1 
ATOM 1807 O O   . GLU A 1 245 ? 136.435 175.827 144.194 1.00 67.99  ? 245 GLU A O   1 
ATOM 1808 C CB  . GLU A 1 245 ? 135.674 175.934 140.951 1.00 69.40  ? 245 GLU A CB  1 
ATOM 1809 C CG  . GLU A 1 245 ? 134.372 176.151 140.201 1.00 73.80  ? 245 GLU A CG  1 
ATOM 1810 C CD  . GLU A 1 245 ? 134.581 176.786 138.840 1.00 83.20  ? 245 GLU A CD  1 
ATOM 1811 O OE1 . GLU A 1 245 ? 135.528 177.586 138.691 1.00 82.73  ? 245 GLU A OE1 1 
ATOM 1812 O OE2 . GLU A 1 245 ? 133.795 176.485 137.917 1.00 79.89  ? 245 GLU A OE2 1 
ATOM 1813 N N   . ALA A 1 246 ? 138.154 176.278 142.813 1.00 71.05  ? 246 ALA A N   1 
ATOM 1814 C CA  . ALA A 1 246 ? 139.128 175.683 143.720 1.00 66.31  ? 246 ALA A CA  1 
ATOM 1815 C C   . ALA A 1 246 ? 139.153 176.417 145.053 1.00 71.38  ? 246 ALA A C   1 
ATOM 1816 O O   . ALA A 1 246 ? 139.184 175.792 146.118 1.00 75.84  ? 246 ALA A O   1 
ATOM 1817 C CB  . ALA A 1 246 ? 140.513 175.690 143.076 1.00 70.68  ? 246 ALA A CB  1 
ATOM 1818 N N   . MET A 1 247 ? 139.139 177.751 145.013 1.00 70.82  ? 247 MET A N   1 
ATOM 1819 C CA  . MET A 1 247 ? 139.156 178.523 146.251 1.00 62.58  ? 247 MET A CA  1 
ATOM 1820 C C   . MET A 1 247 ? 137.921 178.236 147.093 1.00 68.07  ? 247 MET A C   1 
ATOM 1821 O O   . MET A 1 247 ? 138.020 178.055 148.312 1.00 68.73  ? 247 MET A O   1 
ATOM 1822 C CB  . MET A 1 247 ? 139.243 180.015 145.935 1.00 67.66  ? 247 MET A CB  1 
ATOM 1823 C CG  . MET A 1 247 ? 140.510 180.426 145.211 1.00 70.18  ? 247 MET A CG  1 
ATOM 1824 S SD  . MET A 1 247 ? 140.748 182.213 145.206 1.00 89.70  ? 247 MET A SD  1 
ATOM 1825 C CE  . MET A 1 247 ? 139.244 182.756 144.401 1.00 74.44  ? 247 MET A CE  1 
ATOM 1826 N N   . LEU A 1 248 ? 136.748 178.197 146.462 1.00 61.64  ? 248 LEU A N   1 
ATOM 1827 C CA  . LEU A 1 248 ? 135.517 177.958 147.206 1.00 57.25  ? 248 LEU A CA  1 
ATOM 1828 C C   . LEU A 1 248 ? 135.508 176.566 147.825 1.00 58.29  ? 248 LEU A C   1 
ATOM 1829 O O   . LEU A 1 248 ? 135.110 176.397 148.985 1.00 63.34  ? 248 LEU A O   1 
ATOM 1830 C CB  . LEU A 1 248 ? 134.313 178.148 146.287 1.00 56.21  ? 248 LEU A CB  1 
ATOM 1831 C CG  . LEU A 1 248 ? 132.937 178.217 146.949 1.00 61.39  ? 248 LEU A CG  1 
ATOM 1832 C CD1 . LEU A 1 248 ? 132.894 179.293 148.019 1.00 65.55  ? 248 LEU A CD1 1 
ATOM 1833 C CD2 . LEU A 1 248 ? 131.874 178.473 145.900 1.00 65.55  ? 248 LEU A CD2 1 
ATOM 1834 N N   . VAL A 1 249 ? 135.945 175.557 147.072 1.00 57.71  ? 249 VAL A N   1 
ATOM 1835 C CA  . VAL A 1 249 ? 135.961 174.203 147.612 1.00 53.91  ? 249 VAL A CA  1 
ATOM 1836 C C   . VAL A 1 249 ? 136.979 174.090 148.739 1.00 61.01  ? 249 VAL A C   1 
ATOM 1837 O O   . VAL A 1 249 ? 136.749 173.387 149.728 1.00 69.22  ? 249 VAL A O   1 
ATOM 1838 C CB  . VAL A 1 249 ? 136.235 173.182 146.495 1.00 53.79  ? 249 VAL A CB  1 
ATOM 1839 C CG1 . VAL A 1 249 ? 136.507 171.808 147.089 1.00 50.84  ? 249 VAL A CG1 1 
ATOM 1840 C CG2 . VAL A 1 249 ? 135.059 173.131 145.534 1.00 59.78  ? 249 VAL A CG2 1 
ATOM 1841 N N   . ALA A 1 250 ? 138.121 174.769 148.612 1.00 68.13  ? 250 ALA A N   1 
ATOM 1842 C CA  . ALA A 1 250 ? 139.102 174.753 149.692 1.00 66.92  ? 250 ALA A CA  1 
ATOM 1843 C C   . ALA A 1 250 ? 138.547 175.416 150.943 1.00 62.25  ? 250 ALA A C   1 
ATOM 1844 O O   . ALA A 1 250 ? 138.750 174.926 152.059 1.00 65.33  ? 250 ALA A O   1 
ATOM 1845 C CB  . ALA A 1 250 ? 140.386 175.448 149.245 1.00 65.54  ? 250 ALA A CB  1 
ATOM 1846 N N   . PHE A 1 251 ? 137.842 176.536 150.776 1.00 64.57  ? 251 PHE A N   1 
ATOM 1847 C CA  . PHE A 1 251 ? 137.224 177.198 151.919 1.00 64.74  ? 251 PHE A CA  1 
ATOM 1848 C C   . PHE A 1 251 ? 136.212 176.283 152.595 1.00 59.45  ? 251 PHE A C   1 
ATOM 1849 O O   . PHE A 1 251 ? 136.185 176.169 153.824 1.00 64.32  ? 251 PHE A O   1 
ATOM 1850 C CB  . PHE A 1 251 ? 136.554 178.496 151.468 1.00 59.49  ? 251 PHE A CB  1 
ATOM 1851 C CG  . PHE A 1 251 ? 136.144 179.390 152.599 1.00 62.13  ? 251 PHE A CG  1 
ATOM 1852 C CD1 . PHE A 1 251 ? 137.004 180.361 153.079 1.00 67.56  ? 251 PHE A CD1 1 
ATOM 1853 C CD2 . PHE A 1 251 ? 134.897 179.261 153.183 1.00 62.66  ? 251 PHE A CD2 1 
ATOM 1854 C CE1 . PHE A 1 251 ? 136.628 181.186 154.119 1.00 64.13  ? 251 PHE A CE1 1 
ATOM 1855 C CE2 . PHE A 1 251 ? 134.516 180.082 154.223 1.00 63.19  ? 251 PHE A CE2 1 
ATOM 1856 C CZ  . PHE A 1 251 ? 135.383 181.046 154.691 1.00 59.59  ? 251 PHE A CZ  1 
ATOM 1857 N N   . SER A 1 252 ? 135.375 175.615 151.803 1.00 60.89  ? 252 SER A N   1 
ATOM 1858 C CA  . SER A 1 252 ? 134.325 174.784 152.384 1.00 62.15  ? 252 SER A CA  1 
ATOM 1859 C C   . SER A 1 252 ? 134.896 173.525 153.028 1.00 64.31  ? 252 SER A C   1 
ATOM 1860 O O   . SER A 1 252 ? 134.363 173.042 154.033 1.00 66.13  ? 252 SER A O   1 
ATOM 1861 C CB  . SER A 1 252 ? 133.300 174.417 151.314 1.00 62.19  ? 252 SER A CB  1 
ATOM 1862 O OG  . SER A 1 252 ? 132.863 175.570 150.618 1.00 71.16  ? 252 SER A OG  1 
ATOM 1863 N N   . THR A 1 253 ? 135.978 172.982 152.470 1.00 61.21  ? 253 THR A N   1 
ATOM 1864 C CA  . THR A 1 253 ? 136.477 171.676 152.878 1.00 55.41  ? 253 THR A CA  1 
ATOM 1865 C C   . THR A 1 253 ? 137.495 171.741 154.007 1.00 57.24  ? 253 THR A C   1 
ATOM 1866 O O   . THR A 1 253 ? 137.616 170.773 154.765 1.00 64.86  ? 253 THR A O   1 
ATOM 1867 C CB  . THR A 1 253 ? 137.111 170.961 151.681 1.00 55.34  ? 253 THR A CB  1 
ATOM 1868 O OG1 . THR A 1 253 ? 136.265 171.101 150.534 1.00 67.42  ? 253 THR A OG1 1 
ATOM 1869 C CG2 . THR A 1 253 ? 137.295 169.488 151.978 1.00 64.69  ? 253 THR A CG2 1 
ATOM 1870 N N   . CYS A 1 254 ? 138.231 172.843 154.134 1.00 58.91  ? 254 CYS A N   1 
ATOM 1871 C CA  . CYS A 1 254 ? 139.216 173.017 155.201 1.00 64.22  ? 254 CYS A CA  1 
ATOM 1872 C C   . CYS A 1 254 ? 140.344 171.995 155.115 1.00 61.73  ? 254 CYS A C   1 
ATOM 1873 O O   . CYS A 1 254 ? 140.909 171.602 156.139 1.00 64.43  ? 254 CYS A O   1 
ATOM 1874 C CB  . CYS A 1 254 ? 138.556 172.940 156.580 1.00 69.16  ? 254 CYS A CB  1 
ATOM 1875 S SG  . CYS A 1 254 ? 137.266 174.161 156.851 1.00 77.19  ? 254 CYS A SG  1 
ATOM 1876 N N   . SER A 1 255 ? 140.691 171.551 153.910 1.00 58.32  ? 255 SER A N   1 
ATOM 1877 C CA  . SER A 1 255 ? 141.790 170.615 153.731 1.00 68.69  ? 255 SER A CA  1 
ATOM 1878 C C   . SER A 1 255 ? 142.324 170.716 152.312 1.00 68.14  ? 255 SER A C   1 
ATOM 1879 O O   . SER A 1 255 ? 141.577 170.550 151.344 1.00 68.27  ? 255 SER A O   1 
ATOM 1880 C CB  . SER A 1 255 ? 141.350 169.178 154.023 1.00 67.53  ? 255 SER A CB  1 
ATOM 1881 O OG  . SER A 1 255 ? 140.245 168.814 153.220 1.00 74.07  ? 255 SER A OG  1 
ATOM 1882 N N   . SER A 1 256 ? 143.626 170.987 152.199 1.00 64.08  ? 256 SER A N   1 
ATOM 1883 C CA  . SER A 1 256 ? 144.247 171.110 150.886 1.00 65.85  ? 256 SER A CA  1 
ATOM 1884 C C   . SER A 1 256 ? 144.301 169.768 150.171 1.00 65.90  ? 256 SER A C   1 
ATOM 1885 O O   . SER A 1 256 ? 144.153 169.705 148.945 1.00 68.86  ? 256 SER A O   1 
ATOM 1886 C CB  . SER A 1 256 ? 145.650 171.696 151.026 1.00 76.62  ? 256 SER A CB  1 
ATOM 1887 O OG  . SER A 1 256 ? 145.644 172.826 151.881 1.00 75.68  ? 256 SER A OG  1 
ATOM 1888 N N   . ALA A 1 257 ? 144.527 168.683 150.914 1.00 59.80  ? 257 ALA A N   1 
ATOM 1889 C CA  . ALA A 1 257 ? 144.617 167.368 150.289 1.00 66.89  ? 257 ALA A CA  1 
ATOM 1890 C C   . ALA A 1 257 ? 143.302 166.986 149.622 1.00 66.63  ? 257 ALA A C   1 
ATOM 1891 O O   . ALA A 1 257 ? 143.289 166.509 148.481 1.00 61.72  ? 257 ALA A O   1 
ATOM 1892 C CB  . ALA A 1 257 ? 145.019 166.322 151.328 1.00 66.08  ? 257 ALA A CB  1 
ATOM 1893 N N   . ALA A 1 258 ? 142.181 167.193 150.316 1.00 66.53  ? 258 ALA A N   1 
ATOM 1894 C CA  . ALA A 1 258 ? 140.883 166.863 149.742 1.00 57.57  ? 258 ALA A CA  1 
ATOM 1895 C C   . ALA A 1 258 ? 140.503 167.794 148.601 1.00 56.50  ? 258 ALA A C   1 
ATOM 1896 O O   . ALA A 1 258 ? 139.728 167.395 147.727 1.00 63.50  ? 258 ALA A O   1 
ATOM 1897 C CB  . ALA A 1 258 ? 139.803 166.906 150.822 1.00 55.82  ? 258 ALA A CB  1 
ATOM 1898 N N   . THR A 1 259 ? 141.017 169.023 148.593 1.00 64.16  ? 259 THR A N   1 
ATOM 1899 C CA  . THR A 1 259 ? 140.743 169.954 147.507 1.00 60.91  ? 259 THR A CA  1 
ATOM 1900 C C   . THR A 1 259 ? 141.711 169.809 146.342 1.00 63.62  ? 259 THR A C   1 
ATOM 1901 O O   . THR A 1 259 ? 141.484 170.420 145.294 1.00 65.45  ? 259 THR A O   1 
ATOM 1902 C CB  . THR A 1 259 ? 140.794 171.394 148.021 1.00 62.48  ? 259 THR A CB  1 
ATOM 1903 O OG1 . THR A 1 259 ? 140.064 171.494 149.249 1.00 73.37  ? 259 THR A OG1 1 
ATOM 1904 C CG2 . THR A 1 259 ? 140.200 172.347 146.999 1.00 62.78  ? 259 THR A CG2 1 
ATOM 1905 N N   . LEU A 1 260 ? 142.771 169.020 146.494 1.00 64.63  ? 260 LEU A N   1 
ATOM 1906 C CA  . LEU A 1 260 ? 143.735 168.858 145.411 1.00 59.56  ? 260 LEU A CA  1 
ATOM 1907 C C   . LEU A 1 260 ? 143.092 168.445 144.096 1.00 60.15  ? 260 LEU A C   1 
ATOM 1908 O O   . LEU A 1 260 ? 143.482 168.995 143.053 1.00 64.44  ? 260 LEU A O   1 
ATOM 1909 C CB  . LEU A 1 260 ? 144.810 167.842 145.824 1.00 62.03  ? 260 LEU A CB  1 
ATOM 1910 C CG  . LEU A 1 260 ? 145.849 167.507 144.754 1.00 63.10  ? 260 LEU A CG  1 
ATOM 1911 C CD1 . LEU A 1 260 ? 146.502 168.767 144.216 1.00 63.47  ? 260 LEU A CD1 1 
ATOM 1912 C CD2 . LEU A 1 260 ? 146.898 166.567 145.312 1.00 64.90  ? 260 LEU A CD2 1 
ATOM 1913 N N   . PRO A 1 261 ? 142.138 167.512 144.055 1.00 56.51  ? 261 PRO A N   1 
ATOM 1914 C CA  . PRO A 1 261 ? 141.510 167.186 142.766 1.00 59.14  ? 261 PRO A CA  1 
ATOM 1915 C C   . PRO A 1 261 ? 140.924 168.398 142.065 1.00 71.35  ? 261 PRO A C   1 
ATOM 1916 O O   . PRO A 1 261 ? 141.051 168.520 140.842 1.00 74.60  ? 261 PRO A O   1 
ATOM 1917 C CB  . PRO A 1 261 ? 140.425 166.173 143.159 1.00 56.94  ? 261 PRO A CB  1 
ATOM 1918 C CG  . PRO A 1 261 ? 140.909 165.569 144.422 1.00 56.31  ? 261 PRO A CG  1 
ATOM 1919 C CD  . PRO A 1 261 ? 141.626 166.665 145.145 1.00 56.39  ? 261 PRO A CD  1 
ATOM 1920 N N   . VAL A 1 262 ? 140.295 169.309 142.809 1.00 68.01  ? 262 VAL A N   1 
ATOM 1921 C CA  . VAL A 1 262 ? 139.699 170.488 142.190 1.00 60.05  ? 262 VAL A CA  1 
ATOM 1922 C C   . VAL A 1 262 ? 140.775 171.456 141.713 1.00 62.15  ? 262 VAL A C   1 
ATOM 1923 O O   . VAL A 1 262 ? 140.637 172.080 140.656 1.00 69.33  ? 262 VAL A O   1 
ATOM 1924 C CB  . VAL A 1 262 ? 138.721 171.165 143.163 1.00 60.79  ? 262 VAL A CB  1 
ATOM 1925 C CG1 . VAL A 1 262 ? 137.828 172.132 142.411 1.00 64.98  ? 262 VAL A CG1 1 
ATOM 1926 C CG2 . VAL A 1 262 ? 137.885 170.124 143.883 1.00 62.22  ? 262 VAL A CG2 1 
ATOM 1927 N N   . THR A 1 263 ? 141.849 171.620 142.488 1.00 61.34  ? 263 THR A N   1 
ATOM 1928 C CA  . THR A 1 263 ? 142.936 172.488 142.047 1.00 57.97  ? 263 THR A CA  1 
ATOM 1929 C C   . THR A 1 263 ? 143.552 171.971 140.755 1.00 71.20  ? 263 THR A C   1 
ATOM 1930 O O   . THR A 1 263 ? 143.836 172.749 139.837 1.00 79.04  ? 263 THR A O   1 
ATOM 1931 C CB  . THR A 1 263 ? 144.007 172.604 143.132 1.00 62.64  ? 263 THR A CB  1 
ATOM 1932 O OG1 . THR A 1 263 ? 144.697 171.355 143.262 1.00 76.32  ? 263 THR A OG1 1 
ATOM 1933 C CG2 . THR A 1 263 ? 143.390 172.984 144.467 1.00 69.09  ? 263 THR A CG2 1 
ATOM 1934 N N   . MET A 1 264 ? 143.765 170.658 140.663 1.00 67.88  ? 264 MET A N   1 
ATOM 1935 C CA  . MET A 1 264 ? 144.306 170.083 139.437 1.00 67.47  ? 264 MET A CA  1 
ATOM 1936 C C   . MET A 1 264 ? 143.295 170.136 138.300 1.00 73.24  ? 264 MET A C   1 
ATOM 1937 O O   . MET A 1 264 ? 143.684 170.209 137.132 1.00 70.78  ? 264 MET A O   1 
ATOM 1938 C CB  . MET A 1 264 ? 144.752 168.646 139.690 1.00 60.82  ? 264 MET A CB  1 
ATOM 1939 C CG  . MET A 1 264 ? 145.979 168.547 140.577 1.00 65.47  ? 264 MET A CG  1 
ATOM 1940 S SD  . MET A 1 264 ? 146.362 166.861 141.082 1.00 81.73  ? 264 MET A SD  1 
ATOM 1941 C CE  . MET A 1 264 ? 147.919 166.602 140.237 1.00 67.91  ? 264 MET A CE  1 
ATOM 1942 N N   . ARG A 1 265 ? 142.000 170.089 138.613 1.00 72.59  ? 265 ARG A N   1 
ATOM 1943 C CA  . ARG A 1 265 ? 140.985 170.256 137.580 1.00 68.12  ? 265 ARG A CA  1 
ATOM 1944 C C   . ARG A 1 265 ? 141.050 171.655 136.981 1.00 66.64  ? 265 ARG A C   1 
ATOM 1945 O O   . ARG A 1 265 ? 141.073 171.825 135.758 1.00 72.60  ? 265 ARG A O   1 
ATOM 1946 C CB  . ARG A 1 265 ? 139.598 169.986 138.165 1.00 63.81  ? 265 ARG A CB  1 
ATOM 1947 C CG  . ARG A 1 265 ? 139.003 168.638 137.773 1.00 70.31  ? 265 ARG A CG  1 
ATOM 1948 C CD  . ARG A 1 265 ? 137.477 168.658 137.712 1.00 75.82  ? 265 ARG A CD  1 
ATOM 1949 N NE  . ARG A 1 265 ? 136.945 169.874 137.107 1.00 76.84  ? 265 ARG A NE  1 
ATOM 1950 C CZ  . ARG A 1 265 ? 135.780 170.427 137.419 1.00 76.58  ? 265 ARG A CZ  1 
ATOM 1951 N NH1 . ARG A 1 265 ? 134.977 169.891 138.325 1.00 71.17  ? 265 ARG A NH1 1 
ATOM 1952 N NH2 . ARG A 1 265 ? 135.410 171.547 136.805 1.00 73.44  ? 265 ARG A NH2 1 
ATOM 1953 N N   . VAL A 1 266 ? 141.083 172.676 137.840 1.00 71.62  ? 266 VAL A N   1 
ATOM 1954 C CA  . VAL A 1 266 ? 141.095 174.053 137.361 1.00 74.86  ? 266 VAL A CA  1 
ATOM 1955 C C   . VAL A 1 266 ? 142.435 174.431 136.747 1.00 76.11  ? 266 VAL A C   1 
ATOM 1956 O O   . VAL A 1 266 ? 142.488 175.334 135.904 1.00 80.44  ? 266 VAL A O   1 
ATOM 1957 C CB  . VAL A 1 266 ? 140.734 175.030 138.496 1.00 71.68  ? 266 VAL A CB  1 
ATOM 1958 C CG1 . VAL A 1 266 ? 139.371 174.689 139.077 1.00 73.30  ? 266 VAL A CG1 1 
ATOM 1959 C CG2 . VAL A 1 266 ? 141.798 175.014 139.579 1.00 76.48  ? 266 VAL A CG2 1 
ATOM 1960 N N   . ALA A 1 267 ? 143.526 173.774 137.147 1.00 67.23  ? 267 ALA A N   1 
ATOM 1961 C CA  . ALA A 1 267 ? 144.835 174.134 136.611 1.00 70.81  ? 267 ALA A CA  1 
ATOM 1962 C C   . ALA A 1 267 ? 144.880 173.955 135.100 1.00 76.98  ? 267 ALA A C   1 
ATOM 1963 O O   . ALA A 1 267 ? 145.353 174.838 134.375 1.00 78.53  ? 267 ALA A O   1 
ATOM 1964 C CB  . ALA A 1 267 ? 145.924 173.300 137.283 1.00 72.94  ? 267 ALA A CB  1 
ATOM 1965 N N   . GLU A 1 268 ? 144.386 172.819 134.603 1.00 88.62  ? 268 GLU A N   1 
ATOM 1966 C CA  . GLU A 1 268 ? 144.274 172.637 133.160 1.00 88.77  ? 268 GLU A CA  1 
ATOM 1967 C C   . GLU A 1 268 ? 143.296 173.630 132.550 1.00 92.18  ? 268 GLU A C   1 
ATOM 1968 O O   . GLU A 1 268 ? 143.540 174.143 131.451 1.00 90.18  ? 268 GLU A O   1 
ATOM 1969 C CB  . GLU A 1 268 ? 143.858 171.200 132.837 1.00 86.55  ? 268 GLU A CB  1 
ATOM 1970 C CG  . GLU A 1 268 ? 144.946 170.147 133.063 1.00 89.83  ? 268 GLU A CG  1 
ATOM 1971 C CD  . GLU A 1 268 ? 145.713 170.333 134.354 1.00 94.51  ? 268 GLU A CD  1 
ATOM 1972 O OE1 . GLU A 1 268 ? 146.925 170.031 134.376 1.00 90.23  ? 268 GLU A OE1 1 
ATOM 1973 O OE2 . GLU A 1 268 ? 145.117 170.811 135.334 1.00 94.22  ? 268 GLU A OE2 1 
ATOM 1974 N N   . GLU A 1 269 ? 142.193 173.921 133.243 1.00 89.52  ? 269 GLU A N   1 
ATOM 1975 C CA  . GLU A 1 269 ? 141.294 174.971 132.784 1.00 87.68  ? 269 GLU A CA  1 
ATOM 1976 C C   . GLU A 1 269 ? 141.997 176.318 132.701 1.00 88.87  ? 269 GLU A C   1 
ATOM 1977 O O   . GLU A 1 269 ? 141.567 177.183 131.930 1.00 90.14  ? 269 GLU A O   1 
ATOM 1978 C CB  . GLU A 1 269 ? 140.085 175.078 133.713 1.00 87.30  ? 269 GLU A CB  1 
ATOM 1979 C CG  . GLU A 1 269 ? 139.295 173.790 133.868 1.00 88.40  ? 269 GLU A CG  1 
ATOM 1980 C CD  . GLU A 1 269 ? 138.485 173.453 132.636 1.00 94.21  ? 269 GLU A CD  1 
ATOM 1981 O OE1 . GLU A 1 269 ? 138.509 174.245 131.672 1.00 94.95  ? 269 GLU A OE1 1 
ATOM 1982 O OE2 . GLU A 1 269 ? 137.819 172.396 132.633 1.00 95.49  ? 269 GLU A OE2 1 
ATOM 1983 N N   . LEU A 1 270 ? 143.064 176.512 133.476 1.00 85.22  ? 270 LEU A N   1 
ATOM 1984 C CA  . LEU A 1 270 ? 143.847 177.736 133.395 1.00 84.56  ? 270 LEU A CA  1 
ATOM 1985 C C   . LEU A 1 270 ? 144.721 177.764 132.148 1.00 83.65  ? 270 LEU A C   1 
ATOM 1986 O O   . LEU A 1 270 ? 145.060 178.850 131.667 1.00 83.75  ? 270 LEU A O   1 
ATOM 1987 C CB  . LEU A 1 270 ? 144.707 177.876 134.657 1.00 84.46  ? 270 LEU A CB  1 
ATOM 1988 C CG  . LEU A 1 270 ? 145.284 179.244 135.043 1.00 88.93  ? 270 LEU A CG  1 
ATOM 1989 C CD1 . LEU A 1 270 ? 146.215 179.818 133.986 1.00 87.89  ? 270 LEU A CD1 1 
ATOM 1990 C CD2 . LEU A 1 270 ? 144.153 180.219 135.342 1.00 85.94  ? 270 LEU A CD2 1 
ATOM 1991 N N   . GLY A 1 271 ? 145.062 176.601 131.598 1.00 73.42  ? 271 GLY A N   1 
ATOM 1992 C CA  . GLY A 1 271 ? 145.807 176.546 130.356 1.00 78.07  ? 271 GLY A CA  1 
ATOM 1993 C C   . GLY A 1 271 ? 147.309 176.481 130.497 1.00 82.71  ? 271 GLY A C   1 
ATOM 1994 O O   . GLY A 1 271 ? 148.011 176.492 129.482 1.00 76.94  ? 271 GLY A O   1 
ATOM 1995 N N   . VAL A 1 272 ? 147.832 176.412 131.717 1.00 91.11  ? 272 VAL A N   1 
ATOM 1996 C CA  . VAL A 1 272 ? 149.269 176.239 131.915 1.00 88.99  ? 272 VAL A CA  1 
ATOM 1997 C C   . VAL A 1 272 ? 149.631 174.844 131.420 1.00 89.72  ? 272 VAL A C   1 
ATOM 1998 O O   . VAL A 1 272 ? 148.771 173.951 131.425 1.00 89.57  ? 272 VAL A O   1 
ATOM 1999 C CB  . VAL A 1 272 ? 149.672 176.429 133.386 1.00 82.67  ? 272 VAL A CB  1 
ATOM 2000 C CG1 . VAL A 1 272 ? 149.229 177.796 133.888 1.00 82.26  ? 272 VAL A CG1 1 
ATOM 2001 C CG2 . VAL A 1 272 ? 149.100 175.311 134.249 1.00 79.19  ? 272 VAL A CG2 1 
ATOM 2002 N N   . PRO A 1 273 ? 150.864 174.608 130.978 1.00 91.00  ? 273 PRO A N   1 
ATOM 2003 C CA  . PRO A 1 273 ? 151.231 173.262 130.522 1.00 91.00  ? 273 PRO A CA  1 
ATOM 2004 C C   . PRO A 1 273 ? 150.892 172.215 131.570 1.00 89.21  ? 273 PRO A C   1 
ATOM 2005 O O   . PRO A 1 273 ? 151.242 172.345 132.745 1.00 82.90  ? 273 PRO A O   1 
ATOM 2006 C CB  . PRO A 1 273 ? 152.742 173.357 130.280 1.00 87.81  ? 273 PRO A CB  1 
ATOM 2007 C CG  . PRO A 1 273 ? 153.088 174.800 130.283 1.00 90.43  ? 273 PRO A CG  1 
ATOM 2008 C CD  . PRO A 1 273 ? 151.928 175.603 130.762 1.00 86.75  ? 273 PRO A CD  1 
ATOM 2009 N N   . GLU A 1 274 ? 150.201 171.161 131.130 1.00 96.13  ? 274 GLU A N   1 
ATOM 2010 C CA  . GLU A 1 274 ? 149.721 170.141 132.054 1.00 93.64  ? 274 GLU A CA  1 
ATOM 2011 C C   . GLU A 1 274 ? 150.852 169.479 132.826 1.00 90.14  ? 274 GLU A C   1 
ATOM 2012 O O   . GLU A 1 274 ? 150.652 169.100 133.983 1.00 91.93  ? 274 GLU A O   1 
ATOM 2013 C CB  . GLU A 1 274 ? 148.922 169.078 131.297 1.00 95.52  ? 274 GLU A CB  1 
ATOM 2014 C CG  . GLU A 1 274 ? 147.706 169.619 130.561 1.00 95.24  ? 274 GLU A CG  1 
ATOM 2015 C CD  . GLU A 1 274 ? 148.004 169.995 129.122 1.00 93.58  ? 274 GLU A CD  1 
ATOM 2016 O OE1 . GLU A 1 274 ? 149.193 170.148 128.776 1.00 91.50  ? 274 GLU A OE1 1 
ATOM 2017 O OE2 . GLU A 1 274 ? 147.045 170.138 128.335 1.00 93.42  ? 274 GLU A OE2 1 
ATOM 2018 N N   . SER A 1 275 ? 152.027 169.325 132.216 1.00 79.37  ? 275 SER A N   1 
ATOM 2019 C CA  . SER A 1 275 ? 153.153 168.738 132.934 1.00 79.90  ? 275 SER A CA  1 
ATOM 2020 C C   . SER A 1 275 ? 153.565 169.608 134.115 1.00 84.95  ? 275 SER A C   1 
ATOM 2021 O O   . SER A 1 275 ? 153.804 169.101 135.220 1.00 87.34  ? 275 SER A O   1 
ATOM 2022 C CB  . SER A 1 275 ? 154.327 168.539 131.978 1.00 80.84  ? 275 SER A CB  1 
ATOM 2023 O OG  . SER A 1 275 ? 154.660 169.753 131.328 1.00 82.42  ? 275 SER A OG  1 
ATOM 2024 N N   . ILE A 1 276 ? 153.650 170.923 133.903 1.00 84.92  ? 276 ILE A N   1 
ATOM 2025 C CA  . ILE A 1 276 ? 154.058 171.818 134.978 1.00 85.61  ? 276 ILE A CA  1 
ATOM 2026 C C   . ILE A 1 276 ? 153.050 171.793 136.117 1.00 79.62  ? 276 ILE A C   1 
ATOM 2027 O O   . ILE A 1 276 ? 153.435 171.697 137.287 1.00 74.53  ? 276 ILE A O   1 
ATOM 2028 C CB  . ILE A 1 276 ? 154.253 173.245 134.439 1.00 79.02  ? 276 ILE A CB  1 
ATOM 2029 C CG1 . ILE A 1 276 ? 155.314 173.243 133.335 1.00 79.81  ? 276 ILE A CG1 1 
ATOM 2030 C CG2 . ILE A 1 276 ? 154.640 174.193 135.571 1.00 72.87  ? 276 ILE A CG2 1 
ATOM 2031 C CD1 . ILE A 1 276 ? 155.676 174.615 132.820 1.00 80.65  ? 276 ILE A CD1 1 
ATOM 2032 N N   . ALA A 1 277 ? 151.757 171.877 135.809 1.00 79.67  ? 277 ALA A N   1 
ATOM 2033 C CA  . ALA A 1 277 ? 150.749 171.814 136.861 1.00 81.67  ? 277 ALA A CA  1 
ATOM 2034 C C   . ALA A 1 277 ? 150.813 170.481 137.589 1.00 78.44  ? 277 ALA A C   1 
ATOM 2035 O O   . ALA A 1 277 ? 150.783 170.427 138.824 1.00 76.34  ? 277 ALA A O   1 
ATOM 2036 C CB  . ALA A 1 277 ? 149.360 172.036 136.265 1.00 80.09  ? 277 ALA A CB  1 
ATOM 2037 N N   . SER A 1 278 ? 150.915 169.387 136.834 1.00 74.58  ? 278 SER A N   1 
ATOM 2038 C CA  . SER A 1 278 ? 150.904 168.064 137.442 1.00 81.65  ? 278 SER A CA  1 
ATOM 2039 C C   . SER A 1 278 ? 152.068 167.878 138.401 1.00 78.49  ? 278 SER A C   1 
ATOM 2040 O O   . SER A 1 278 ? 151.881 167.350 139.503 1.00 80.34  ? 278 SER A O   1 
ATOM 2041 C CB  . SER A 1 278 ? 150.943 166.992 136.354 1.00 81.07  ? 278 SER A CB  1 
ATOM 2042 O OG  . SER A 1 278 ? 149.880 167.160 135.433 1.00 84.43  ? 278 SER A OG  1 
ATOM 2043 N N   . PHE A 1 279 ? 153.269 168.302 138.011 1.00 69.53  ? 279 PHE A N   1 
ATOM 2044 C CA  . PHE A 1 279 ? 154.430 168.079 138.864 1.00 76.25  ? 279 PHE A CA  1 
ATOM 2045 C C   . PHE A 1 279 ? 154.305 168.862 140.169 1.00 77.86  ? 279 PHE A C   1 
ATOM 2046 O O   . PHE A 1 279 ? 154.620 168.346 141.248 1.00 72.12  ? 279 PHE A O   1 
ATOM 2047 C CB  . PHE A 1 279 ? 155.708 168.465 138.113 1.00 76.11  ? 279 PHE A CB  1 
ATOM 2048 C CG  . PHE A 1 279 ? 156.818 168.961 139.002 1.00 80.95  ? 279 PHE A CG  1 
ATOM 2049 C CD1 . PHE A 1 279 ? 157.254 168.206 140.081 1.00 76.07  ? 279 PHE A CD1 1 
ATOM 2050 C CD2 . PHE A 1 279 ? 157.420 170.183 138.764 1.00 74.84  ? 279 PHE A CD2 1 
ATOM 2051 C CE1 . PHE A 1 279 ? 158.266 168.659 140.898 1.00 69.47  ? 279 PHE A CE1 1 
ATOM 2052 C CE2 . PHE A 1 279 ? 158.433 170.641 139.580 1.00 76.51  ? 279 PHE A CE2 1 
ATOM 2053 C CZ  . PHE A 1 279 ? 158.857 169.877 140.648 1.00 77.43  ? 279 PHE A CZ  1 
ATOM 2054 N N   . THR A 1 280 ? 153.832 170.109 140.094 1.00 73.44  ? 280 THR A N   1 
ATOM 2055 C CA  . THR A 1 280 ? 153.953 171.016 141.232 1.00 70.85  ? 280 THR A CA  1 
ATOM 2056 C C   . THR A 1 280 ? 152.741 170.963 142.157 1.00 73.41  ? 280 THR A C   1 
ATOM 2057 O O   . THR A 1 280 ? 152.898 170.975 143.382 1.00 77.49  ? 280 THR A O   1 
ATOM 2058 C CB  . THR A 1 280 ? 154.176 172.453 140.752 1.00 77.65  ? 280 THR A CB  1 
ATOM 2059 O OG1 . THR A 1 280 ? 152.943 173.004 140.275 1.00 75.52  ? 280 THR A OG1 1 
ATOM 2060 C CG2 . THR A 1 280 ? 155.239 172.519 139.661 1.00 78.02  ? 280 THR A CG2 1 
ATOM 2061 N N   . LEU A 1 281 ? 151.528 170.919 141.604 1.00 72.39  ? 281 LEU A N   1 
ATOM 2062 C CA  . LEU A 1 281 ? 150.345 171.121 142.436 1.00 67.53  ? 281 LEU A CA  1 
ATOM 2063 C C   . LEU A 1 281 ? 150.302 170.210 143.656 1.00 73.28  ? 281 LEU A C   1 
ATOM 2064 O O   . LEU A 1 281 ? 150.101 170.727 144.769 1.00 75.45  ? 281 LEU A O   1 
ATOM 2065 C CB  . LEU A 1 281 ? 149.080 170.930 141.592 1.00 64.91  ? 281 LEU A CB  1 
ATOM 2066 C CG  . LEU A 1 281 ? 148.291 172.200 141.279 1.00 69.90  ? 281 LEU A CG  1 
ATOM 2067 C CD1 . LEU A 1 281 ? 149.024 173.031 140.249 1.00 73.31  ? 281 LEU A CD1 1 
ATOM 2068 C CD2 . LEU A 1 281 ? 146.898 171.857 140.794 1.00 73.25  ? 281 LEU A CD2 1 
ATOM 2069 N N   . PRO A 1 282 ? 150.466 168.890 143.539 1.00 61.86  ? 282 PRO A N   1 
ATOM 2070 C CA  . PRO A 1 282 ? 150.464 168.055 144.752 1.00 57.69  ? 282 PRO A CA  1 
ATOM 2071 C C   . PRO A 1 282 ? 151.567 168.417 145.728 1.00 64.93  ? 282 PRO A C   1 
ATOM 2072 O O   . PRO A 1 282 ? 151.338 168.461 146.946 1.00 66.15  ? 282 PRO A O   1 
ATOM 2073 C CB  . PRO A 1 282 ? 150.640 166.634 144.197 1.00 58.43  ? 282 PRO A CB  1 
ATOM 2074 C CG  . PRO A 1 282 ? 150.231 166.715 142.767 1.00 54.53  ? 282 PRO A CG  1 
ATOM 2075 C CD  . PRO A 1 282 ? 150.588 168.089 142.311 1.00 58.38  ? 282 PRO A CD  1 
ATOM 2076 N N   . LEU A 1 283 ? 152.766 168.695 145.218 1.00 68.41  ? 283 LEU A N   1 
ATOM 2077 C CA  . LEU A 1 283 ? 153.883 169.034 146.090 1.00 66.79  ? 283 LEU A CA  1 
ATOM 2078 C C   . LEU A 1 283 ? 153.576 170.292 146.891 1.00 66.16  ? 283 LEU A C   1 
ATOM 2079 O O   . LEU A 1 283 ? 153.775 170.335 148.111 1.00 68.75  ? 283 LEU A O   1 
ATOM 2080 C CB  . LEU A 1 283 ? 155.147 169.225 145.252 1.00 66.02  ? 283 LEU A CB  1 
ATOM 2081 C CG  . LEU A 1 283 ? 156.500 169.300 145.960 1.00 70.02  ? 283 LEU A CG  1 
ATOM 2082 C CD1 . LEU A 1 283 ? 156.596 168.298 147.096 1.00 66.24  ? 283 LEU A CD1 1 
ATOM 2083 C CD2 . LEU A 1 283 ? 157.618 169.086 144.957 1.00 73.30  ? 283 LEU A CD2 1 
ATOM 2084 N N   . GLY A 1 284 ? 153.080 171.328 146.215 1.00 59.13  ? 284 GLY A N   1 
ATOM 2085 C CA  . GLY A 1 284 ? 152.721 172.546 146.915 1.00 54.79  ? 284 GLY A CA  1 
ATOM 2086 C C   . GLY A 1 284 ? 151.604 172.328 147.913 1.00 57.16  ? 284 GLY A C   1 
ATOM 2087 O O   . GLY A 1 284 ? 151.664 172.815 149.044 1.00 69.08  ? 284 GLY A O   1 
ATOM 2088 N N   . ALA A 1 285 ? 150.562 171.600 147.506 1.00 67.15  ? 285 ALA A N   1 
ATOM 2089 C CA  . ALA A 1 285 ? 149.472 171.314 148.429 1.00 72.07  ? 285 ALA A CA  1 
ATOM 2090 C C   . ALA A 1 285 ? 149.984 170.628 149.684 1.00 70.58  ? 285 ALA A C   1 
ATOM 2091 O O   . ALA A 1 285 ? 149.441 170.841 150.775 1.00 61.64  ? 285 ALA A O   1 
ATOM 2092 C CB  . ALA A 1 285 ? 148.415 170.449 147.744 1.00 60.98  ? 285 ALA A CB  1 
ATOM 2093 N N   . THR A 1 286 ? 151.023 169.803 149.554 1.00 72.83  ? 286 THR A N   1 
ATOM 2094 C CA  . THR A 1 286 ? 151.569 169.130 150.726 1.00 68.33  ? 286 THR A CA  1 
ATOM 2095 C C   . THR A 1 286 ? 152.467 170.051 151.548 1.00 67.45  ? 286 THR A C   1 
ATOM 2096 O O   . THR A 1 286 ? 152.510 169.932 152.778 1.00 72.18  ? 286 THR A O   1 
ATOM 2097 C CB  . THR A 1 286 ? 152.336 167.878 150.302 1.00 71.29  ? 286 THR A CB  1 
ATOM 2098 O OG1 . THR A 1 286 ? 151.406 166.846 149.953 1.00 74.10  ? 286 THR A OG1 1 
ATOM 2099 C CG2 . THR A 1 286 ? 153.217 167.381 151.432 1.00 66.70  ? 286 THR A CG2 1 
ATOM 2100 N N   . ILE A 1 287 ? 153.191 170.967 150.904 1.00 71.18  ? 287 ILE A N   1 
ATOM 2101 C CA  . ILE A 1 287 ? 154.166 171.821 151.579 1.00 69.39  ? 287 ILE A CA  1 
ATOM 2102 C C   . ILE A 1 287 ? 153.716 173.278 151.621 1.00 74.45  ? 287 ILE A C   1 
ATOM 2103 O O   . ILE A 1 287 ? 153.773 173.920 152.669 1.00 77.70  ? 287 ILE A O   1 
ATOM 2104 C CB  . ILE A 1 287 ? 155.560 171.700 150.925 1.00 72.03  ? 287 ILE A CB  1 
ATOM 2105 C CG1 . ILE A 1 287 ? 156.112 170.287 151.091 1.00 71.07  ? 287 ILE A CG1 1 
ATOM 2106 C CG2 . ILE A 1 287 ? 156.518 172.715 151.522 1.00 77.95  ? 287 ILE A CG2 1 
ATOM 2107 C CD1 . ILE A 1 287 ? 156.892 169.809 149.901 1.00 71.45  ? 287 ILE A CD1 1 
ATOM 2108 N N   . ASN A 1 288 ? 153.270 173.820 150.490 1.00 73.71  ? 288 ASN A N   1 
ATOM 2109 C CA  . ASN A 1 288 ? 153.071 175.261 150.393 1.00 70.28  ? 288 ASN A CA  1 
ATOM 2110 C C   . ASN A 1 288 ? 151.877 175.713 151.222 1.00 72.42  ? 288 ASN A C   1 
ATOM 2111 O O   . ASN A 1 288 ? 150.827 176.064 150.676 1.00 73.34  ? 288 ASN A O   1 
ATOM 2112 C CB  . ASN A 1 288 ? 152.878 175.676 148.935 1.00 75.10  ? 288 ASN A CB  1 
ATOM 2113 C CG  . ASN A 1 288 ? 152.734 177.173 148.774 1.00 73.34  ? 288 ASN A CG  1 
ATOM 2114 O OD1 . ASN A 1 288 ? 153.624 177.937 149.144 1.00 68.87  ? 288 ASN A OD1 1 
ATOM 2115 N ND2 . ASN A 1 288 ? 151.607 177.602 148.223 1.00 73.86  ? 288 ASN A ND2 1 
ATOM 2116 N N   . MET A 1 289 ? 152.037 175.710 152.541 1.00 79.91  ? 289 MET A N   1 
ATOM 2117 C CA  . MET A 1 289 ? 150.983 176.132 153.463 1.00 80.69  ? 289 MET A CA  1 
ATOM 2118 C C   . MET A 1 289 ? 151.213 177.575 153.913 1.00 79.83  ? 289 MET A C   1 
ATOM 2119 O O   . MET A 1 289 ? 151.535 177.854 155.066 1.00 83.86  ? 289 MET A O   1 
ATOM 2120 C CB  . MET A 1 289 ? 150.921 175.183 154.658 1.00 83.86  ? 289 MET A CB  1 
ATOM 2121 C CG  . MET A 1 289 ? 150.901 173.702 154.294 1.00 82.68  ? 289 MET A CG  1 
ATOM 2122 S SD  . MET A 1 289 ? 149.238 173.012 154.239 1.00 94.52  ? 289 MET A SD  1 
ATOM 2123 C CE  . MET A 1 289 ? 149.344 171.778 155.532 1.00 78.35  ? 289 MET A CE  1 
ATOM 2124 N N   . ASP A 1 290 ? 151.045 178.505 152.970 1.00 83.31  ? 290 ASP A N   1 
ATOM 2125 C CA  . ASP A 1 290 ? 151.234 179.918 153.285 1.00 83.03  ? 290 ASP A CA  1 
ATOM 2126 C C   . ASP A 1 290 ? 150.245 180.384 154.345 1.00 84.00  ? 290 ASP A C   1 
ATOM 2127 O O   . ASP A 1 290 ? 150.628 181.047 155.319 1.00 90.32  ? 290 ASP A O   1 
ATOM 2128 C CB  . ASP A 1 290 ? 151.083 180.757 152.018 1.00 83.75  ? 290 ASP A CB  1 
ATOM 2129 C CG  . ASP A 1 290 ? 152.338 180.771 151.174 1.00 89.76  ? 290 ASP A CG  1 
ATOM 2130 O OD1 . ASP A 1 290 ? 153.307 180.068 151.530 1.00 93.90  ? 290 ASP A OD1 1 
ATOM 2131 O OD2 . ASP A 1 290 ? 152.354 181.482 150.148 1.00 88.05  ? 290 ASP A OD2 1 
ATOM 2132 N N   . GLY A 1 291 ? 148.967 180.049 154.173 1.00 77.84  ? 291 GLY A N   1 
ATOM 2133 C CA  . GLY A 1 291 ? 147.975 180.441 155.157 1.00 74.30  ? 291 GLY A CA  1 
ATOM 2134 C C   . GLY A 1 291 ? 148.268 179.867 156.527 1.00 77.97  ? 291 GLY A C   1 
ATOM 2135 O O   . GLY A 1 291 ? 148.060 180.529 157.546 1.00 84.12  ? 291 GLY A O   1 
ATOM 2136 N N   . THR A 1 292 ? 148.754 178.626 156.572 1.00 74.49  ? 292 THR A N   1 
ATOM 2137 C CA  . THR A 1 292 ? 149.088 178.014 157.852 1.00 71.35  ? 292 THR A CA  1 
ATOM 2138 C C   . THR A 1 292 ? 150.208 178.777 158.546 1.00 76.63  ? 292 THR A C   1 
ATOM 2139 O O   . THR A 1 292 ? 150.156 179.009 159.757 1.00 84.44  ? 292 THR A O   1 
ATOM 2140 C CB  . THR A 1 292 ? 149.477 176.551 157.650 1.00 74.65  ? 292 THR A CB  1 
ATOM 2141 O OG1 . THR A 1 292 ? 148.436 175.874 156.936 1.00 79.46  ? 292 THR A OG1 1 
ATOM 2142 C CG2 . THR A 1 292 ? 149.693 175.869 158.989 1.00 79.24  ? 292 THR A CG2 1 
ATOM 2143 N N   . ALA A 1 293 ? 151.234 179.177 157.794 1.00 79.75  ? 293 ALA A N   1 
ATOM 2144 C CA  . ALA A 1 293 ? 152.330 179.936 158.389 1.00 76.10  ? 293 ALA A CA  1 
ATOM 2145 C C   . ALA A 1 293 ? 151.844 181.290 158.890 1.00 74.85  ? 293 ALA A C   1 
ATOM 2146 O O   . ALA A 1 293 ? 152.226 181.741 159.979 1.00 80.95  ? 293 ALA A O   1 
ATOM 2147 C CB  . ALA A 1 293 ? 153.456 180.110 157.373 1.00 72.90  ? 293 ALA A CB  1 
ATOM 2148 N N   . LEU A 1 294 ? 151.004 181.960 158.100 1.00 71.68  ? 294 LEU A N   1 
ATOM 2149 C CA  . LEU A 1 294 ? 150.471 183.248 158.530 1.00 70.55  ? 294 LEU A CA  1 
ATOM 2150 C C   . LEU A 1 294 ? 149.668 183.097 159.814 1.00 71.24  ? 294 LEU A C   1 
ATOM 2151 O O   . LEU A 1 294 ? 149.818 183.887 160.755 1.00 82.55  ? 294 LEU A O   1 
ATOM 2152 C CB  . LEU A 1 294 ? 149.610 183.853 157.424 1.00 68.30  ? 294 LEU A CB  1 
ATOM 2153 C CG  . LEU A 1 294 ? 149.039 185.237 157.727 1.00 70.82  ? 294 LEU A CG  1 
ATOM 2154 C CD1 . LEU A 1 294 ? 149.053 186.095 156.476 1.00 77.99  ? 294 LEU A CD1 1 
ATOM 2155 C CD2 . LEU A 1 294 ? 147.632 185.137 158.290 1.00 76.91  ? 294 LEU A CD2 1 
ATOM 2156 N N   . TYR A 1 295 ? 148.811 182.077 159.874 1.00 72.84  ? 295 TYR A N   1 
ATOM 2157 C CA  . TYR A 1 295 ? 148.028 181.848 161.081 1.00 74.74  ? 295 TYR A CA  1 
ATOM 2158 C C   . TYR A 1 295 ? 148.926 181.519 162.262 1.00 79.91  ? 295 TYR A C   1 
ATOM 2159 O O   . TYR A 1 295 ? 148.647 181.930 163.389 1.00 87.82  ? 295 TYR A O   1 
ATOM 2160 C CB  . TYR A 1 295 ? 147.026 180.720 160.864 1.00 73.37  ? 295 TYR A CB  1 
ATOM 2161 C CG  . TYR A 1 295 ? 146.633 180.039 162.152 1.00 72.28  ? 295 TYR A CG  1 
ATOM 2162 C CD1 . TYR A 1 295 ? 145.779 180.656 163.052 1.00 75.74  ? 295 TYR A CD1 1 
ATOM 2163 C CD2 . TYR A 1 295 ? 147.127 178.783 162.475 1.00 77.01  ? 295 TYR A CD2 1 
ATOM 2164 C CE1 . TYR A 1 295 ? 145.420 180.040 164.231 1.00 78.44  ? 295 TYR A CE1 1 
ATOM 2165 C CE2 . TYR A 1 295 ? 146.774 178.159 163.652 1.00 79.87  ? 295 TYR A CE2 1 
ATOM 2166 C CZ  . TYR A 1 295 ? 145.920 178.792 164.526 1.00 82.20  ? 295 TYR A CZ  1 
ATOM 2167 O OH  . TYR A 1 295 ? 145.564 178.175 165.702 1.00 86.84  ? 295 TYR A OH  1 
ATOM 2168 N N   . GLN A 1 296 ? 149.991 180.750 162.032 1.00 82.98  ? 296 GLN A N   1 
ATOM 2169 C CA  . GLN A 1 296 ? 150.902 180.416 163.120 1.00 85.83  ? 296 GLN A CA  1 
ATOM 2170 C C   . GLN A 1 296 ? 151.547 181.671 163.691 1.00 88.37  ? 296 GLN A C   1 
ATOM 2171 O O   . GLN A 1 296 ? 151.620 181.847 164.913 1.00 94.05  ? 296 GLN A O   1 
ATOM 2172 C CB  . GLN A 1 296 ? 151.968 179.439 162.628 1.00 82.97  ? 296 GLN A CB  1 
ATOM 2173 C CG  . GLN A 1 296 ? 151.483 178.009 162.507 1.00 84.50  ? 296 GLN A CG  1 
ATOM 2174 C CD  . GLN A 1 296 ? 152.532 177.089 161.920 1.00 88.64  ? 296 GLN A CD  1 
ATOM 2175 O OE1 . GLN A 1 296 ? 153.675 177.489 161.706 1.00 89.32  ? 296 GLN A OE1 1 
ATOM 2176 N NE2 . GLN A 1 296 ? 152.149 175.846 161.659 1.00 92.84  ? 296 GLN A NE2 1 
ATOM 2177 N N   . GLY A 1 297 ? 152.017 182.562 162.819 1.00 74.18  ? 297 GLY A N   1 
ATOM 2178 C CA  . GLY A 1 297 ? 152.580 183.813 163.305 1.00 75.16  ? 297 GLY A CA  1 
ATOM 2179 C C   . GLY A 1 297 ? 151.561 184.639 164.066 1.00 79.26  ? 297 GLY A C   1 
ATOM 2180 O O   . GLY A 1 297 ? 151.845 185.176 165.147 1.00 87.19  ? 297 GLY A O   1 
ATOM 2181 N N   . VAL A 1 298 ? 150.350 184.745 163.515 1.00 70.52  ? 298 VAL A N   1 
ATOM 2182 C CA  . VAL A 1 298 ? 149.307 185.526 164.168 1.00 71.83  ? 298 VAL A CA  1 
ATOM 2183 C C   . VAL A 1 298 ? 148.998 184.951 165.542 1.00 73.18  ? 298 VAL A C   1 
ATOM 2184 O O   . VAL A 1 298 ? 148.845 185.690 166.517 1.00 83.05  ? 298 VAL A O   1 
ATOM 2185 C CB  . VAL A 1 298 ? 148.048 185.585 163.283 1.00 75.83  ? 298 VAL A CB  1 
ATOM 2186 C CG1 . VAL A 1 298 ? 146.865 186.117 164.076 1.00 75.25  ? 298 VAL A CG1 1 
ATOM 2187 C CG2 . VAL A 1 298 ? 148.303 186.452 162.059 1.00 83.41  ? 298 VAL A CG2 1 
ATOM 2188 N N   . ALA A 1 299 ? 148.905 183.625 165.642 1.00 77.24  ? 299 ALA A N   1 
ATOM 2189 C CA  . ALA A 1 299 ? 148.573 182.994 166.914 1.00 81.86  ? 299 ALA A CA  1 
ATOM 2190 C C   . ALA A 1 299 ? 149.701 183.155 167.922 1.00 85.72  ? 299 ALA A C   1 
ATOM 2191 O O   . ALA A 1 299 ? 149.450 183.326 169.120 1.00 88.45  ? 299 ALA A O   1 
ATOM 2192 C CB  . ALA A 1 299 ? 148.257 181.516 166.698 1.00 83.11  ? 299 ALA A CB  1 
ATOM 2193 N N   . ALA A 1 300 ? 150.951 183.088 167.464 1.00 85.37  ? 300 ALA A N   1 
ATOM 2194 C CA  . ALA A 1 300 ? 152.071 183.320 168.369 1.00 83.90  ? 300 ALA A CA  1 
ATOM 2195 C C   . ALA A 1 300 ? 151.999 184.719 168.963 1.00 86.03  ? 300 ALA A C   1 
ATOM 2196 O O   . ALA A 1 300 ? 152.102 184.899 170.183 1.00 90.90  ? 300 ALA A O   1 
ATOM 2197 C CB  . ALA A 1 300 ? 153.393 183.111 167.632 1.00 83.72  ? 300 ALA A CB  1 
ATOM 2198 N N   . ILE A 1 301 ? 151.798 185.728 168.113 1.00 83.24  ? 301 ILE A N   1 
ATOM 2199 C CA  . ILE A 1 301 ? 151.688 187.092 168.627 1.00 78.81  ? 301 ILE A CA  1 
ATOM 2200 C C   . ILE A 1 301 ? 150.468 187.224 169.532 1.00 81.02  ? 301 ILE A C   1 
ATOM 2201 O O   . ILE A 1 301 ? 150.502 187.929 170.548 1.00 77.55  ? 301 ILE A O   1 
ATOM 2202 C CB  . ILE A 1 301 ? 151.645 188.101 167.466 1.00 77.67  ? 301 ILE A CB  1 
ATOM 2203 C CG1 . ILE A 1 301 ? 152.961 188.076 166.688 1.00 81.10  ? 301 ILE A CG1 1 
ATOM 2204 C CG2 . ILE A 1 301 ? 151.356 189.498 167.989 1.00 79.46  ? 301 ILE A CG2 1 
ATOM 2205 C CD1 . ILE A 1 301 ? 154.170 188.529 167.485 1.00 80.46  ? 301 ILE A CD1 1 
ATOM 2206 N N   . PHE A 1 302 ? 149.374 186.549 169.179 1.00 91.86  ? 302 PHE A N   1 
ATOM 2207 C CA  . PHE A 1 302 ? 148.151 186.623 169.969 1.00 84.72  ? 302 PHE A CA  1 
ATOM 2208 C C   . PHE A 1 302 ? 148.378 186.102 171.380 1.00 89.57  ? 302 PHE A C   1 
ATOM 2209 O O   . PHE A 1 302 ? 148.019 186.755 172.364 1.00 94.71  ? 302 PHE A O   1 
ATOM 2210 C CB  . PHE A 1 302 ? 147.045 185.833 169.267 1.00 85.44  ? 302 PHE A CB  1 
ATOM 2211 C CG  . PHE A 1 302 ? 145.888 185.476 170.155 1.00 91.94  ? 302 PHE A CG  1 
ATOM 2212 C CD1 . PHE A 1 302 ? 145.829 184.240 170.775 1.00 89.61  ? 302 PHE A CD1 1 
ATOM 2213 C CD2 . PHE A 1 302 ? 144.850 186.368 170.357 1.00 92.67  ? 302 PHE A CD2 1 
ATOM 2214 C CE1 . PHE A 1 302 ? 144.763 183.905 171.586 1.00 87.85  ? 302 PHE A CE1 1 
ATOM 2215 C CE2 . PHE A 1 302 ? 143.780 186.037 171.167 1.00 88.56  ? 302 PHE A CE2 1 
ATOM 2216 C CZ  . PHE A 1 302 ? 143.738 184.804 171.781 1.00 85.62  ? 302 PHE A CZ  1 
ATOM 2217 N N   . VAL A 1 303 ? 148.976 184.916 171.501 1.00 91.77  ? 303 VAL A N   1 
ATOM 2218 C CA  . VAL A 1 303 ? 149.211 184.357 172.828 1.00 92.92  ? 303 VAL A CA  1 
ATOM 2219 C C   . VAL A 1 303 ? 150.242 185.186 173.585 1.00 91.69  ? 303 VAL A C   1 
ATOM 2220 O O   . VAL A 1 303 ? 150.136 185.352 174.808 1.00 90.35  ? 303 VAL A O   1 
ATOM 2221 C CB  . VAL A 1 303 ? 149.621 182.875 172.736 1.00 89.29  ? 303 VAL A CB  1 
ATOM 2222 C CG1 . VAL A 1 303 ? 148.535 182.073 172.038 1.00 90.00  ? 303 VAL A CG1 1 
ATOM 2223 C CG2 . VAL A 1 303 ? 150.943 182.709 172.015 1.00 89.00  ? 303 VAL A CG2 1 
ATOM 2224 N N   . ALA A 1 304 ? 151.246 185.727 172.888 1.00 92.92  ? 304 ALA A N   1 
ATOM 2225 C CA  . ALA A 1 304 ? 152.219 186.578 173.562 1.00 92.72  ? 304 ALA A CA  1 
ATOM 2226 C C   . ALA A 1 304 ? 151.538 187.795 174.170 1.00 93.32  ? 304 ALA A C   1 
ATOM 2227 O O   . ALA A 1 304 ? 151.814 188.171 175.315 1.00 97.12  ? 304 ALA A O   1 
ATOM 2228 C CB  . ALA A 1 304 ? 153.312 187.003 172.582 1.00 92.89  ? 304 ALA A CB  1 
ATOM 2229 N N   . GLN A 1 305 ? 150.636 188.423 173.416 1.00 90.87  ? 305 GLN A N   1 
ATOM 2230 C CA  . GLN A 1 305 ? 149.887 189.556 173.950 1.00 91.65  ? 305 GLN A CA  1 
ATOM 2231 C C   . GLN A 1 305 ? 148.990 189.121 175.101 1.00 88.80  ? 305 GLN A C   1 
ATOM 2232 O O   . GLN A 1 305 ? 148.875 189.821 176.114 1.00 89.30  ? 305 GLN A O   1 
ATOM 2233 C CB  . GLN A 1 305 ? 149.060 190.203 172.841 1.00 93.74  ? 305 GLN A CB  1 
ATOM 2234 C CG  . GLN A 1 305 ? 149.875 191.024 171.861 1.00 93.49  ? 305 GLN A CG  1 
ATOM 2235 C CD  . GLN A 1 305 ? 149.105 191.346 170.600 1.00 93.86  ? 305 GLN A CD  1 
ATOM 2236 O OE1 . GLN A 1 305 ? 147.959 190.930 170.436 1.00 95.51  ? 305 GLN A OE1 1 
ATOM 2237 N NE2 . GLN A 1 305 ? 149.730 192.096 169.702 1.00 95.13  ? 305 GLN A NE2 1 
ATOM 2238 N N   . ALA A 1 306 ? 148.345 187.963 174.962 1.00 90.11  ? 306 ALA A N   1 
ATOM 2239 C CA  . ALA A 1 306 ? 147.417 187.505 175.990 1.00 93.92  ? 306 ALA A CA  1 
ATOM 2240 C C   . ALA A 1 306 ? 148.130 187.296 177.318 1.00 95.56  ? 306 ALA A C   1 
ATOM 2241 O O   . ALA A 1 306 ? 147.620 187.679 178.377 1.00 94.58  ? 306 ALA A O   1 
ATOM 2242 C CB  . ALA A 1 306 ? 146.732 186.216 175.537 1.00 96.49  ? 306 ALA A CB  1 
ATOM 2243 N N   . TYR A 1 307 ? 149.314 186.692 177.283 1.00 101.91 ? 307 TYR A N   1 
ATOM 2244 C CA  . TYR A 1 307 ? 150.078 186.442 178.498 1.00 100.36 ? 307 TYR A CA  1 
ATOM 2245 C C   . TYR A 1 307 ? 151.046 187.568 178.832 1.00 100.25 ? 307 TYR A C   1 
ATOM 2246 O O   . TYR A 1 307 ? 151.824 187.434 179.782 1.00 100.11 ? 307 TYR A O   1 
ATOM 2247 C CB  . TYR A 1 307 ? 150.832 185.115 178.378 1.00 95.74  ? 307 TYR A CB  1 
ATOM 2248 C CG  . TYR A 1 307 ? 149.922 183.917 178.512 1.00 96.72  ? 307 TYR A CG  1 
ATOM 2249 C CD1 . TYR A 1 307 ? 149.506 183.477 179.760 1.00 98.59  ? 307 TYR A CD1 1 
ATOM 2250 C CD2 . TYR A 1 307 ? 149.462 183.238 177.393 1.00 100.03 ? 307 TYR A CD2 1 
ATOM 2251 C CE1 . TYR A 1 307 ? 148.669 182.388 179.891 1.00 100.83 ? 307 TYR A CE1 1 
ATOM 2252 C CE2 . TYR A 1 307 ? 148.623 182.147 177.515 1.00 101.67 ? 307 TYR A CE2 1 
ATOM 2253 C CZ  . TYR A 1 307 ? 148.230 181.727 178.766 1.00 102.59 ? 307 TYR A CZ  1 
ATOM 2254 O OH  . TYR A 1 307 ? 147.395 180.642 178.895 1.00 101.94 ? 307 TYR A OH  1 
ATOM 2255 N N   . GLY A 1 308 ? 151.020 188.666 178.081 1.00 94.92  ? 308 GLY A N   1 
ATOM 2256 C CA  . GLY A 1 308 ? 151.781 189.846 178.433 1.00 92.83  ? 308 GLY A CA  1 
ATOM 2257 C C   . GLY A 1 308 ? 153.254 189.798 178.102 1.00 92.71  ? 308 GLY A C   1 
ATOM 2258 O O   . GLY A 1 308 ? 154.005 190.657 178.579 1.00 94.39  ? 308 GLY A O   1 
ATOM 2259 N N   . VAL A 1 309 ? 153.698 188.831 177.305 1.00 95.01  ? 309 VAL A N   1 
ATOM 2260 C CA  . VAL A 1 309 ? 155.102 188.740 176.922 1.00 96.26  ? 309 VAL A CA  1 
ATOM 2261 C C   . VAL A 1 309 ? 155.339 189.725 175.782 1.00 100.04 ? 309 VAL A C   1 
ATOM 2262 O O   . VAL A 1 309 ? 154.694 189.643 174.734 1.00 99.20  ? 309 VAL A O   1 
ATOM 2263 C CB  . VAL A 1 309 ? 155.485 187.314 176.514 1.00 96.15  ? 309 VAL A CB  1 
ATOM 2264 C CG1 . VAL A 1 309 ? 156.976 187.228 176.215 1.00 96.58  ? 309 VAL A CG1 1 
ATOM 2265 C CG2 . VAL A 1 309 ? 155.100 186.329 177.607 1.00 95.00  ? 309 VAL A CG2 1 
ATOM 2266 N N   . GLU A 1 310 ? 156.264 190.663 175.987 1.00 109.68 ? 310 GLU A N   1 
ATOM 2267 C CA  . GLU A 1 310 ? 156.595 191.669 174.978 1.00 108.30 ? 310 GLU A CA  1 
ATOM 2268 C C   . GLU A 1 310 ? 157.788 191.166 174.172 1.00 107.18 ? 310 GLU A C   1 
ATOM 2269 O O   . GLU A 1 310 ? 158.948 191.480 174.445 1.00 106.90 ? 310 GLU A O   1 
ATOM 2270 C CB  . GLU A 1 310 ? 156.881 193.013 175.634 1.00 110.42 ? 310 GLU A CB  1 
ATOM 2271 C CG  . GLU A 1 310 ? 155.686 193.619 176.356 1.00 110.07 ? 310 GLU A CG  1 
ATOM 2272 C CD  . GLU A 1 310 ? 154.629 194.142 175.403 1.00 110.84 ? 310 GLU A CD  1 
ATOM 2273 O OE1 . GLU A 1 310 ? 154.985 194.530 174.270 1.00 111.19 ? 310 GLU A OE1 1 
ATOM 2274 O OE2 . GLU A 1 310 ? 153.441 194.165 175.788 1.00 107.81 ? 310 GLU A OE2 1 
ATOM 2275 N N   . LEU A 1 311 ? 157.487 190.363 173.156 1.00 104.13 ? 311 LEU A N   1 
ATOM 2276 C CA  . LEU A 1 311 ? 158.532 189.799 172.313 1.00 104.11 ? 311 LEU A CA  1 
ATOM 2277 C C   . LEU A 1 311 ? 159.256 190.907 171.559 1.00 103.70 ? 311 LEU A C   1 
ATOM 2278 O O   . LEU A 1 311 ? 158.623 191.793 170.977 1.00 100.63 ? 311 LEU A O   1 
ATOM 2279 C CB  . LEU A 1 311 ? 157.932 188.795 171.331 1.00 101.57 ? 311 LEU A CB  1 
ATOM 2280 C CG  . LEU A 1 311 ? 157.239 187.583 171.957 1.00 100.78 ? 311 LEU A CG  1 
ATOM 2281 C CD1 . LEU A 1 311 ? 156.571 186.743 170.884 1.00 96.29  ? 311 LEU A CD1 1 
ATOM 2282 C CD2 . LEU A 1 311 ? 158.224 186.744 172.756 1.00 100.50 ? 311 LEU A CD2 1 
ATOM 2283 N N   . THR A 1 312 ? 160.584 190.855 171.571 1.00 104.31 ? 312 THR A N   1 
ATOM 2284 C CA  . THR A 1 312 ? 161.393 191.843 170.879 1.00 102.98 ? 312 THR A CA  1 
ATOM 2285 C C   . THR A 1 312 ? 161.542 191.474 169.406 1.00 98.59  ? 312 THR A C   1 
ATOM 2286 O O   . THR A 1 312 ? 161.219 190.364 168.976 1.00 98.74  ? 312 THR A O   1 
ATOM 2287 C CB  . THR A 1 312 ? 162.770 191.963 171.530 1.00 102.20 ? 312 THR A CB  1 
ATOM 2288 O OG1 . THR A 1 312 ? 163.475 190.723 171.395 1.00 101.04 ? 312 THR A OG1 1 
ATOM 2289 C CG2 . THR A 1 312 ? 162.639 192.314 173.004 1.00 101.13 ? 312 THR A CG2 1 
ATOM 2290 N N   . LEU A 1 313 ? 162.044 192.432 168.623 1.00 99.74  ? 313 LEU A N   1 
ATOM 2291 C CA  . LEU A 1 313 ? 162.257 192.178 167.202 1.00 102.50 ? 313 LEU A CA  1 
ATOM 2292 C C   . LEU A 1 313 ? 163.173 190.980 166.994 1.00 100.70 ? 313 LEU A C   1 
ATOM 2293 O O   . LEU A 1 313 ? 162.999 190.214 166.040 1.00 98.50  ? 313 LEU A O   1 
ATOM 2294 C CB  . LEU A 1 313 ? 162.834 193.422 166.525 1.00 103.97 ? 313 LEU A CB  1 
ATOM 2295 C CG  . LEU A 1 313 ? 161.926 194.656 166.512 1.00 104.54 ? 313 LEU A CG  1 
ATOM 2296 C CD1 . LEU A 1 313 ? 162.659 195.853 165.930 1.00 102.33 ? 313 LEU A CD1 1 
ATOM 2297 C CD2 . LEU A 1 313 ? 160.647 194.384 165.735 1.00 100.18 ? 313 LEU A CD2 1 
ATOM 2298 N N   . GLY A 1 314 ? 164.155 190.800 167.877 1.00 103.14 ? 314 GLY A N   1 
ATOM 2299 C CA  . GLY A 1 314 ? 164.976 189.603 167.810 1.00 101.07 ? 314 GLY A CA  1 
ATOM 2300 C C   . GLY A 1 314 ? 164.165 188.339 168.018 1.00 100.47 ? 314 GLY A C   1 
ATOM 2301 O O   . GLY A 1 314 ? 164.347 187.348 167.307 1.00 98.98  ? 314 GLY A O   1 
ATOM 2302 N N   . GLN A 1 315 ? 163.259 188.355 168.999 1.00 101.72 ? 315 GLN A N   1 
ATOM 2303 C CA  . GLN A 1 315 ? 162.373 187.214 169.205 1.00 100.96 ? 315 GLN A CA  1 
ATOM 2304 C C   . GLN A 1 315 ? 161.387 187.071 168.053 1.00 101.64 ? 315 GLN A C   1 
ATOM 2305 O O   . GLN A 1 315 ? 161.088 185.953 167.620 1.00 98.20  ? 315 GLN A O   1 
ATOM 2306 C CB  . GLN A 1 315 ? 161.626 187.361 170.529 1.00 100.01 ? 315 GLN A CB  1 
ATOM 2307 C CG  . GLN A 1 315 ? 162.486 187.120 171.753 1.00 104.04 ? 315 GLN A CG  1 
ATOM 2308 C CD  . GLN A 1 315 ? 162.073 187.978 172.930 1.00 105.24 ? 315 GLN A CD  1 
ATOM 2309 O OE1 . GLN A 1 315 ? 161.962 189.198 172.815 1.00 105.60 ? 315 GLN A OE1 1 
ATOM 2310 N NE2 . GLN A 1 315 ? 161.842 187.343 174.073 1.00 103.14 ? 315 GLN A NE2 1 
ATOM 2311 N N   . GLN A 1 316 ? 160.870 188.192 167.548 1.00 100.13 ? 316 GLN A N   1 
ATOM 2312 C CA  . GLN A 1 316 ? 159.922 188.131 166.441 1.00 96.02  ? 316 GLN A CA  1 
ATOM 2313 C C   . GLN A 1 316 ? 160.570 187.527 165.203 1.00 95.92  ? 316 GLN A C   1 
ATOM 2314 O O   . GLN A 1 316 ? 159.901 186.858 164.406 1.00 94.47  ? 316 GLN A O   1 
ATOM 2315 C CB  . GLN A 1 316 ? 159.375 189.531 166.151 1.00 94.44  ? 316 GLN A CB  1 
ATOM 2316 C CG  . GLN A 1 316 ? 158.941 189.770 164.711 1.00 95.55  ? 316 GLN A CG  1 
ATOM 2317 C CD  . GLN A 1 316 ? 158.398 191.168 164.496 1.00 97.53  ? 316 GLN A CD  1 
ATOM 2318 O OE1 . GLN A 1 316 ? 158.152 191.904 165.451 1.00 95.50  ? 316 GLN A OE1 1 
ATOM 2319 N NE2 . GLN A 1 316 ? 158.209 191.543 163.235 1.00 94.53  ? 316 GLN A NE2 1 
ATOM 2320 N N   . LEU A 1 317 ? 161.872 187.753 165.021 1.00 99.20  ? 317 LEU A N   1 
ATOM 2321 C CA  . LEU A 1 317 ? 162.573 187.161 163.887 1.00 97.82  ? 317 LEU A CA  1 
ATOM 2322 C C   . LEU A 1 317 ? 162.582 185.642 163.981 1.00 96.66  ? 317 LEU A C   1 
ATOM 2323 O O   . LEU A 1 317 ? 162.420 184.955 162.967 1.00 97.26  ? 317 LEU A O   1 
ATOM 2324 C CB  . LEU A 1 317 ? 164.001 187.711 163.820 1.00 95.79  ? 317 LEU A CB  1 
ATOM 2325 C CG  . LEU A 1 317 ? 165.005 187.144 162.807 1.00 96.29  ? 317 LEU A CG  1 
ATOM 2326 C CD1 . LEU A 1 317 ? 165.656 185.853 163.299 1.00 93.90  ? 317 LEU A CD1 1 
ATOM 2327 C CD2 . LEU A 1 317 ? 164.363 186.947 161.441 1.00 96.20  ? 317 LEU A CD2 1 
ATOM 2328 N N   . THR A 1 318 ? 162.761 185.100 165.187 1.00 96.34  ? 318 THR A N   1 
ATOM 2329 C CA  . THR A 1 318 ? 162.749 183.651 165.354 1.00 97.99  ? 318 THR A CA  1 
ATOM 2330 C C   . THR A 1 318 ? 161.424 183.049 164.909 1.00 96.15  ? 318 THR A C   1 
ATOM 2331 O O   . THR A 1 318 ? 161.393 181.911 164.422 1.00 98.29  ? 318 THR A O   1 
ATOM 2332 C CB  . THR A 1 318 ? 163.022 183.289 166.814 1.00 97.27  ? 318 THR A CB  1 
ATOM 2333 O OG1 . THR A 1 318 ? 164.314 183.777 167.199 1.00 99.96  ? 318 THR A OG1 1 
ATOM 2334 C CG2 . THR A 1 318 ? 162.966 181.782 167.014 1.00 94.56  ? 318 THR A CG2 1 
ATOM 2335 N N   . ILE A 1 319 ? 160.326 183.787 165.076 1.00 91.91  ? 319 ILE A N   1 
ATOM 2336 C CA  . ILE A 1 319 ? 159.023 183.279 164.666 1.00 93.79  ? 319 ILE A CA  1 
ATOM 2337 C C   . ILE A 1 319 ? 159.005 183.031 163.167 1.00 93.40  ? 319 ILE A C   1 
ATOM 2338 O O   . ILE A 1 319 ? 158.440 182.039 162.696 1.00 94.98  ? 319 ILE A O   1 
ATOM 2339 C CB  . ILE A 1 319 ? 157.909 184.257 165.088 1.00 93.32  ? 319 ILE A CB  1 
ATOM 2340 C CG1 . ILE A 1 319 ? 157.629 184.182 166.596 1.00 93.50  ? 319 ILE A CG1 1 
ATOM 2341 C CG2 . ILE A 1 319 ? 156.634 183.970 164.308 1.00 94.07  ? 319 ILE A CG2 1 
ATOM 2342 C CD1 . ILE A 1 319 ? 157.616 182.785 167.186 1.00 92.70  ? 319 ILE A CD1 1 
ATOM 2343 N N   . VAL A 1 320 ? 159.619 183.925 162.391 1.00 88.90  ? 320 VAL A N   1 
ATOM 2344 C CA  . VAL A 1 320 ? 159.633 183.761 160.940 1.00 90.47  ? 320 VAL A CA  1 
ATOM 2345 C C   . VAL A 1 320 ? 160.298 182.441 160.568 1.00 91.52  ? 320 VAL A C   1 
ATOM 2346 O O   . VAL A 1 320 ? 159.740 181.627 159.822 1.00 91.61  ? 320 VAL A O   1 
ATOM 2347 C CB  . VAL A 1 320 ? 160.341 184.953 160.273 1.00 90.92  ? 320 VAL A CB  1 
ATOM 2348 C CG1 . VAL A 1 320 ? 160.494 184.717 158.778 1.00 87.18  ? 320 VAL A CG1 1 
ATOM 2349 C CG2 . VAL A 1 320 ? 159.578 186.239 160.546 1.00 85.19  ? 320 VAL A CG2 1 
ATOM 2350 N N   . LEU A 1 321 ? 161.495 182.204 161.106 1.00 90.33  ? 321 LEU A N   1 
ATOM 2351 C CA  . LEU A 1 321 ? 162.231 180.991 160.768 1.00 89.94  ? 321 LEU A CA  1 
ATOM 2352 C C   . LEU A 1 321 ? 161.476 179.751 161.225 1.00 88.54  ? 321 LEU A C   1 
ATOM 2353 O O   . LEU A 1 321 ? 161.348 178.773 160.476 1.00 91.99  ? 321 LEU A O   1 
ATOM 2354 C CB  . LEU A 1 321 ? 163.626 181.045 161.396 1.00 94.13  ? 321 LEU A CB  1 
ATOM 2355 C CG  . LEU A 1 321 ? 164.642 179.959 161.031 1.00 94.91  ? 321 LEU A CG  1 
ATOM 2356 C CD1 . LEU A 1 321 ? 166.018 180.369 161.526 1.00 90.41  ? 321 LEU A CD1 1 
ATOM 2357 C CD2 . LEU A 1 321 ? 164.266 178.598 161.602 1.00 93.35  ? 321 LEU A CD2 1 
ATOM 2358 N N   . THR A 1 322 ? 160.969 179.769 162.460 1.00 92.10  ? 322 THR A N   1 
ATOM 2359 C CA  . THR A 1 322 ? 160.302 178.584 162.987 1.00 99.74  ? 322 THR A CA  1 
ATOM 2360 C C   . THR A 1 322 ? 159.030 178.277 162.207 1.00 98.94  ? 322 THR A C   1 
ATOM 2361 O O   . THR A 1 322 ? 158.747 177.113 161.909 1.00 97.38  ? 322 THR A O   1 
ATOM 2362 C CB  . THR A 1 322 ? 159.997 178.771 164.472 1.00 101.18 ? 322 THR A CB  1 
ATOM 2363 O OG1 . THR A 1 322 ? 161.172 178.482 165.238 1.00 100.47 ? 322 THR A OG1 1 
ATOM 2364 C CG2 . THR A 1 322 ? 158.879 177.840 164.922 1.00 97.68  ? 322 THR A CG2 1 
ATOM 2365 N N   . ALA A 1 323 ? 158.246 179.302 161.869 1.00 87.81  ? 323 ALA A N   1 
ATOM 2366 C CA  . ALA A 1 323 ? 157.036 179.076 161.088 1.00 83.91  ? 323 ALA A CA  1 
ATOM 2367 C C   . ALA A 1 323 ? 157.370 178.573 159.691 1.00 82.33  ? 323 ALA A C   1 
ATOM 2368 O O   . ALA A 1 323 ? 156.679 177.698 159.157 1.00 85.03  ? 323 ALA A O   1 
ATOM 2369 C CB  . ALA A 1 323 ? 156.214 180.360 161.012 1.00 84.26  ? 323 ALA A CB  1 
ATOM 2370 N N   . VAL A 1 324 ? 158.425 179.113 159.078 1.00 83.87  ? 324 VAL A N   1 
ATOM 2371 C CA  . VAL A 1 324 ? 158.827 178.639 157.758 1.00 90.67  ? 324 VAL A CA  1 
ATOM 2372 C C   . VAL A 1 324 ? 159.197 177.162 157.823 1.00 91.25  ? 324 VAL A C   1 
ATOM 2373 O O   . VAL A 1 324 ? 158.845 176.374 156.937 1.00 89.76  ? 324 VAL A O   1 
ATOM 2374 C CB  . VAL A 1 324 ? 159.988 179.490 157.213 1.00 88.27  ? 324 VAL A CB  1 
ATOM 2375 C CG1 . VAL A 1 324 ? 160.621 178.816 156.005 1.00 85.36  ? 324 VAL A CG1 1 
ATOM 2376 C CG2 . VAL A 1 324 ? 159.502 180.889 156.859 1.00 81.79  ? 324 VAL A CG2 1 
ATOM 2377 N N   . LEU A 1 325 ? 159.916 176.766 158.875 1.00 92.73  ? 325 LEU A N   1 
ATOM 2378 C CA  . LEU A 1 325 ? 160.334 175.371 158.993 1.00 90.88  ? 325 LEU A CA  1 
ATOM 2379 C C   . LEU A 1 325 ? 159.164 174.462 159.353 1.00 90.27  ? 325 LEU A C   1 
ATOM 2380 O O   . LEU A 1 325 ? 159.149 173.284 158.978 1.00 93.69  ? 325 LEU A O   1 
ATOM 2381 C CB  . LEU A 1 325 ? 161.446 175.244 160.034 1.00 92.61  ? 325 LEU A CB  1 
ATOM 2382 C CG  . LEU A 1 325 ? 162.883 175.349 159.513 1.00 92.47  ? 325 LEU A CG  1 
ATOM 2383 C CD1 . LEU A 1 325 ? 163.379 173.993 159.031 1.00 90.40  ? 325 LEU A CD1 1 
ATOM 2384 C CD2 . LEU A 1 325 ? 163.004 176.395 158.413 1.00 90.82  ? 325 LEU A CD2 1 
ATOM 2385 N N   . ALA A 1 326 ? 158.175 174.986 160.082 1.00 85.23  ? 326 ALA A N   1 
ATOM 2386 C CA  . ALA A 1 326 ? 157.089 174.143 160.572 1.00 89.06  ? 326 ALA A CA  1 
ATOM 2387 C C   . ALA A 1 326 ? 156.302 173.508 159.436 1.00 92.13  ? 326 ALA A C   1 
ATOM 2388 O O   . ALA A 1 326 ? 155.754 172.412 159.600 1.00 91.47  ? 326 ALA A O   1 
ATOM 2389 C CB  . ALA A 1 326 ? 156.154 174.960 161.463 1.00 91.15  ? 326 ALA A CB  1 
ATOM 2390 N N   . SER A 1 327 ? 156.228 174.171 158.280 1.00 90.07  ? 327 SER A N   1 
ATOM 2391 C CA  . SER A 1 327 ? 155.490 173.606 157.158 1.00 90.60  ? 327 SER A CA  1 
ATOM 2392 C C   . SER A 1 327 ? 156.081 172.281 156.698 1.00 88.22  ? 327 SER A C   1 
ATOM 2393 O O   . SER A 1 327 ? 155.398 171.517 156.007 1.00 82.97  ? 327 SER A O   1 
ATOM 2394 C CB  . SER A 1 327 ? 155.459 174.600 155.996 1.00 87.56  ? 327 SER A CB  1 
ATOM 2395 O OG  . SER A 1 327 ? 154.855 175.820 156.390 1.00 82.58  ? 327 SER A OG  1 
ATOM 2396 N N   . ILE A 1 328 ? 157.327 171.996 157.060 1.00 96.47  ? 328 ILE A N   1 
ATOM 2397 C CA  . ILE A 1 328 ? 157.948 170.713 156.757 1.00 96.36  ? 328 ILE A CA  1 
ATOM 2398 C C   . ILE A 1 328 ? 158.786 170.258 157.948 1.00 92.53  ? 328 ILE A C   1 
ATOM 2399 O O   . ILE A 1 328 ? 158.252 169.922 159.006 1.00 82.90  ? 328 ILE A O   1 
ATOM 2400 C CB  . ILE A 1 328 ? 158.802 170.796 155.477 1.00 93.73  ? 328 ILE A CB  1 
ATOM 2401 C CG1 . ILE A 1 328 ? 159.420 169.433 155.148 1.00 92.27  ? 328 ILE A CG1 1 
ATOM 2402 C CG2 . ILE A 1 328 ? 159.891 171.847 155.629 1.00 84.48  ? 328 ILE A CG2 1 
ATOM 2403 C CD1 . ILE A 1 328 ? 158.411 168.319 154.978 1.00 87.84  ? 328 ILE A CD1 1 
ATOM 2404 N N   . GLY A 1 337 ? 146.227 171.359 161.683 1.00 94.35  ? 337 GLY A N   1 
ATOM 2405 C CA  . GLY A 1 337 ? 146.830 172.673 161.561 1.00 97.14  ? 337 GLY A CA  1 
ATOM 2406 C C   . GLY A 1 337 ? 147.087 173.320 162.907 1.00 102.13 ? 337 GLY A C   1 
ATOM 2407 O O   . GLY A 1 337 ? 148.033 174.089 163.069 1.00 102.41 ? 337 GLY A O   1 
ATOM 2408 N N   . LEU A 1 338 ? 146.228 173.008 163.880 1.00 101.23 ? 338 LEU A N   1 
ATOM 2409 C CA  . LEU A 1 338 ? 146.406 173.547 165.224 1.00 101.43 ? 338 LEU A CA  1 
ATOM 2410 C C   . LEU A 1 338 ? 147.603 172.913 165.923 1.00 103.89 ? 338 LEU A C   1 
ATOM 2411 O O   . LEU A 1 338 ? 148.316 173.585 166.676 1.00 100.19 ? 338 LEU A O   1 
ATOM 2412 C CB  . LEU A 1 338 ? 145.133 173.332 166.043 1.00 100.57 ? 338 LEU A CB  1 
ATOM 2413 C CG  . LEU A 1 338 ? 144.993 174.113 167.353 1.00 103.64 ? 338 LEU A CG  1 
ATOM 2414 C CD1 . LEU A 1 338 ? 145.219 175.603 167.151 1.00 100.38 ? 338 LEU A CD1 1 
ATOM 2415 C CD2 . LEU A 1 338 ? 143.625 173.864 167.969 1.00 102.52 ? 338 LEU A CD2 1 
ATOM 2416 N N   . VAL A 1 339 ? 147.838 171.620 165.689 1.00 104.65 ? 339 VAL A N   1 
ATOM 2417 C CA  . VAL A 1 339 ? 148.898 170.917 166.406 1.00 102.67 ? 339 VAL A CA  1 
ATOM 2418 C C   . VAL A 1 339 ? 150.268 171.456 166.011 1.00 98.42  ? 339 VAL A C   1 
ATOM 2419 O O   . VAL A 1 339 ? 151.164 171.591 166.853 1.00 94.74  ? 339 VAL A O   1 
ATOM 2420 C CB  . VAL A 1 339 ? 148.791 169.398 166.168 1.00 102.39 ? 339 VAL A CB  1 
ATOM 2421 C CG1 . VAL A 1 339 ? 147.352 168.934 166.334 1.00 99.02  ? 339 VAL A CG1 1 
ATOM 2422 C CG2 . VAL A 1 339 ? 149.308 169.030 164.789 1.00 97.44  ? 339 VAL A CG2 1 
ATOM 2423 N N   . MET A 1 340 ? 150.456 171.774 164.727 1.00 95.31  ? 340 MET A N   1 
ATOM 2424 C CA  . MET A 1 340 ? 151.746 172.289 164.280 1.00 96.36  ? 340 MET A CA  1 
ATOM 2425 C C   . MET A 1 340 ? 152.109 173.588 164.987 1.00 99.51  ? 340 MET A C   1 
ATOM 2426 O O   . MET A 1 340 ? 153.294 173.923 165.097 1.00 95.77  ? 340 MET A O   1 
ATOM 2427 C CB  . MET A 1 340 ? 151.734 172.508 162.767 1.00 94.93  ? 340 MET A CB  1 
ATOM 2428 C CG  . MET A 1 340 ? 151.629 171.236 161.942 1.00 98.43  ? 340 MET A CG  1 
ATOM 2429 S SD  . MET A 1 340 ? 149.932 170.708 161.645 1.00 102.81 ? 340 MET A SD  1 
ATOM 2430 C CE  . MET A 1 340 ? 150.139 168.929 161.614 1.00 95.88  ? 340 MET A CE  1 
ATOM 2431 N N   . LEU A 1 341 ? 151.112 174.330 165.470 1.00 101.42 ? 341 LEU A N   1 
ATOM 2432 C CA  . LEU A 1 341 ? 151.387 175.614 166.106 1.00 100.22 ? 341 LEU A CA  1 
ATOM 2433 C C   . LEU A 1 341 ? 152.235 175.450 167.360 1.00 99.51  ? 341 LEU A C   1 
ATOM 2434 O O   . LEU A 1 341 ? 153.010 176.349 167.705 1.00 96.28  ? 341 LEU A O   1 
ATOM 2435 C CB  . LEU A 1 341 ? 150.071 176.320 166.439 1.00 97.62  ? 341 LEU A CB  1 
ATOM 2436 C CG  . LEU A 1 341 ? 150.151 177.566 167.323 1.00 97.23  ? 341 LEU A CG  1 
ATOM 2437 C CD1 . LEU A 1 341 ? 151.010 178.633 166.674 1.00 96.87  ? 341 LEU A CD1 1 
ATOM 2438 C CD2 . LEU A 1 341 ? 148.760 178.105 167.600 1.00 93.91  ? 341 LEU A CD2 1 
ATOM 2439 N N   . THR A 1 342 ? 152.112 174.312 168.048 1.00 108.38 ? 342 THR A N   1 
ATOM 2440 C CA  . THR A 1 342 ? 152.829 174.125 169.305 1.00 106.71 ? 342 THR A CA  1 
ATOM 2441 C C   . THR A 1 342 ? 154.327 174.333 169.137 1.00 102.95 ? 342 THR A C   1 
ATOM 2442 O O   . THR A 1 342 ? 154.985 174.865 170.038 1.00 101.53 ? 342 THR A O   1 
ATOM 2443 C CB  . THR A 1 342 ? 152.557 172.727 169.865 1.00 107.62 ? 342 THR A CB  1 
ATOM 2444 O OG1 . THR A 1 342 ? 153.031 171.738 168.943 1.00 106.90 ? 342 THR A OG1 1 
ATOM 2445 C CG2 . THR A 1 342 ? 151.067 172.524 170.103 1.00 102.85 ? 342 THR A CG2 1 
ATOM 2446 N N   . MET A 1 343 ? 154.884 173.925 167.996 1.00 104.27 ? 343 MET A N   1 
ATOM 2447 C CA  . MET A 1 343 ? 156.306 174.144 167.755 1.00 105.96 ? 343 MET A CA  1 
ATOM 2448 C C   . MET A 1 343 ? 156.628 175.632 167.727 1.00 102.41 ? 343 MET A C   1 
ATOM 2449 O O   . MET A 1 343 ? 157.650 176.066 168.272 1.00 100.27 ? 343 MET A O   1 
ATOM 2450 C CB  . MET A 1 343 ? 156.720 173.468 166.445 1.00 104.78 ? 343 MET A CB  1 
ATOM 2451 C CG  . MET A 1 343 ? 157.996 174.018 165.804 1.00 103.45 ? 343 MET A CG  1 
ATOM 2452 S SD  . MET A 1 343 ? 158.402 173.288 164.199 1.00 109.11 ? 343 MET A SD  1 
ATOM 2453 C CE  . MET A 1 343 ? 157.457 171.765 164.213 1.00 104.10 ? 343 MET A CE  1 
ATOM 2454 N N   . VAL A 1 344 ? 155.765 176.430 167.097 1.00 99.65  ? 344 VAL A N   1 
ATOM 2455 C CA  . VAL A 1 344 ? 156.004 177.868 167.032 1.00 102.26 ? 344 VAL A CA  1 
ATOM 2456 C C   . VAL A 1 344 ? 155.966 178.474 168.426 1.00 104.69 ? 344 VAL A C   1 
ATOM 2457 O O   . VAL A 1 344 ? 156.808 179.308 168.779 1.00 103.19 ? 344 VAL A O   1 
ATOM 2458 C CB  . VAL A 1 344 ? 154.984 178.540 166.094 1.00 101.32 ? 344 VAL A CB  1 
ATOM 2459 C CG1 . VAL A 1 344 ? 155.454 179.934 165.715 1.00 99.20  ? 344 VAL A CG1 1 
ATOM 2460 C CG2 . VAL A 1 344 ? 154.763 177.695 164.848 1.00 99.81  ? 344 VAL A CG2 1 
ATOM 2461 N N   . LEU A 1 345 ? 154.991 178.069 169.241 1.00 106.95 ? 345 LEU A N   1 
ATOM 2462 C CA  . LEU A 1 345 ? 154.919 178.564 170.610 1.00 101.33 ? 345 LEU A CA  1 
ATOM 2463 C C   . LEU A 1 345 ? 156.163 178.172 171.396 1.00 104.89 ? 345 LEU A C   1 
ATOM 2464 O O   . LEU A 1 345 ? 156.762 178.999 172.092 1.00 103.75 ? 345 LEU A O   1 
ATOM 2465 C CB  . LEU A 1 345 ? 153.667 178.018 171.291 1.00 103.79 ? 345 LEU A CB  1 
ATOM 2466 C CG  . LEU A 1 345 ? 152.334 178.564 170.785 1.00 100.01 ? 345 LEU A CG  1 
ATOM 2467 C CD1 . LEU A 1 345 ? 151.273 177.484 170.804 1.00 99.63  ? 345 LEU A CD1 1 
ATOM 2468 C CD2 . LEU A 1 345 ? 151.903 179.740 171.625 1.00 101.02 ? 345 LEU A CD2 1 
ATOM 2469 N N   . THR A 1 346 ? 156.569 176.906 171.288 1.00 114.83 ? 346 THR A N   1 
ATOM 2470 C CA  . THR A 1 346 ? 157.692 176.413 172.076 1.00 113.39 ? 346 THR A CA  1 
ATOM 2471 C C   . THR A 1 346 ? 158.988 177.108 171.682 1.00 109.05 ? 346 THR A C   1 
ATOM 2472 O O   . THR A 1 346 ? 159.825 177.417 172.538 1.00 107.39 ? 346 THR A O   1 
ATOM 2473 C CB  . THR A 1 346 ? 157.823 174.899 171.906 1.00 112.41 ? 346 THR A CB  1 
ATOM 2474 O OG1 . THR A 1 346 ? 156.621 174.259 172.351 1.00 114.42 ? 346 THR A OG1 1 
ATOM 2475 C CG2 . THR A 1 346 ? 159.005 174.367 172.704 1.00 108.74 ? 346 THR A CG2 1 
ATOM 2476 N N   . SER A 1 347 ? 159.172 177.363 170.385 1.00 104.60 ? 347 SER A N   1 
ATOM 2477 C CA  . SER A 1 347 ? 160.449 177.883 169.909 1.00 106.20 ? 347 SER A CA  1 
ATOM 2478 C C   . SER A 1 347 ? 160.854 179.157 170.638 1.00 102.72 ? 347 SER A C   1 
ATOM 2479 O O   . SER A 1 347 ? 162.034 179.337 170.959 1.00 104.04 ? 347 SER A O   1 
ATOM 2480 C CB  . SER A 1 347 ? 160.378 178.137 168.404 1.00 106.53 ? 347 SER A CB  1 
ATOM 2481 O OG  . SER A 1 347 ? 159.547 179.246 168.114 1.00 106.73 ? 347 SER A OG  1 
ATOM 2482 N N   . VAL A 1 348 ? 159.900 180.045 170.912 1.00 98.51  ? 348 VAL A N   1 
ATOM 2483 C CA  . VAL A 1 348 ? 160.208 181.315 171.561 1.00 102.31 ? 348 VAL A CA  1 
ATOM 2484 C C   . VAL A 1 348 ? 159.823 181.340 173.038 1.00 103.37 ? 348 VAL A C   1 
ATOM 2485 O O   . VAL A 1 348 ? 160.265 182.244 173.763 1.00 100.12 ? 348 VAL A O   1 
ATOM 2486 C CB  . VAL A 1 348 ? 159.534 182.483 170.814 1.00 103.39 ? 348 VAL A CB  1 
ATOM 2487 C CG1 . VAL A 1 348 ? 160.199 182.694 169.468 1.00 103.93 ? 348 VAL A CG1 1 
ATOM 2488 C CG2 . VAL A 1 348 ? 158.060 182.205 170.625 1.00 103.53 ? 348 VAL A CG2 1 
ATOM 2489 N N   . GLY A 1 349 ? 159.019 180.391 173.501 1.00 105.33 ? 349 GLY A N   1 
ATOM 2490 C CA  . GLY A 1 349 ? 158.784 180.216 174.918 1.00 103.76 ? 349 GLY A CA  1 
ATOM 2491 C C   . GLY A 1 349 ? 157.436 180.655 175.447 1.00 104.28 ? 349 GLY A C   1 
ATOM 2492 O O   . GLY A 1 349 ? 157.285 180.761 176.669 1.00 103.80 ? 349 GLY A O   1 
ATOM 2493 N N   . LEU A 1 350 ? 156.456 180.911 174.585 1.00 100.46 ? 350 LEU A N   1 
ATOM 2494 C CA  . LEU A 1 350 ? 155.132 181.244 175.081 1.00 97.71  ? 350 LEU A CA  1 
ATOM 2495 C C   . LEU A 1 350 ? 154.492 180.017 175.731 1.00 94.08  ? 350 LEU A C   1 
ATOM 2496 O O   . LEU A 1 350 ? 154.725 178.886 175.299 1.00 94.97  ? 350 LEU A O   1 
ATOM 2497 C CB  . LEU A 1 350 ? 154.234 181.753 173.956 1.00 97.80  ? 350 LEU A CB  1 
ATOM 2498 C CG  . LEU A 1 350 ? 154.499 183.151 173.393 1.00 98.66  ? 350 LEU A CG  1 
ATOM 2499 C CD1 . LEU A 1 350 ? 154.622 184.185 174.501 1.00 99.61  ? 350 LEU A CD1 1 
ATOM 2500 C CD2 . LEU A 1 350 ? 155.735 183.150 172.527 1.00 96.15  ? 350 LEU A CD2 1 
ATOM 2501 N N   . PRO A 1 351 ? 153.683 180.212 176.774 1.00 96.89  ? 351 PRO A N   1 
ATOM 2502 C CA  . PRO A 1 351 ? 153.012 179.065 177.407 1.00 101.80 ? 351 PRO A CA  1 
ATOM 2503 C C   . PRO A 1 351 ? 152.177 178.308 176.385 1.00 102.71 ? 351 PRO A C   1 
ATOM 2504 O O   . PRO A 1 351 ? 151.497 178.910 175.553 1.00 103.47 ? 351 PRO A O   1 
ATOM 2505 C CB  . PRO A 1 351 ? 152.135 179.702 178.494 1.00 101.40 ? 351 PRO A CB  1 
ATOM 2506 C CG  . PRO A 1 351 ? 152.384 181.163 178.462 1.00 102.68 ? 351 PRO A CG  1 
ATOM 2507 C CD  . PRO A 1 351 ? 153.473 181.473 177.503 1.00 99.41  ? 351 PRO A CD  1 
ATOM 2508 N N   . LEU A 1 352 ? 152.230 176.978 176.455 1.00 107.80 ? 352 LEU A N   1 
ATOM 2509 C CA  . LEU A 1 352 ? 151.475 176.159 175.515 1.00 108.33 ? 352 LEU A CA  1 
ATOM 2510 C C   . LEU A 1 352 ? 149.985 176.153 175.823 1.00 108.63 ? 352 LEU A C   1 
ATOM 2511 O O   . LEU A 1 352 ? 149.196 175.695 174.991 1.00 108.30 ? 352 LEU A O   1 
ATOM 2512 C CB  . LEU A 1 352 ? 152.014 174.729 175.518 1.00 110.70 ? 352 LEU A CB  1 
ATOM 2513 C CG  . LEU A 1 352 ? 153.270 174.512 174.671 1.00 111.47 ? 352 LEU A CG  1 
ATOM 2514 C CD1 . LEU A 1 352 ? 154.486 175.139 175.338 1.00 108.48 ? 352 LEU A CD1 1 
ATOM 2515 C CD2 . LEU A 1 352 ? 153.499 173.031 174.419 1.00 111.02 ? 352 LEU A CD2 1 
ATOM 2516 N N   . GLU A 1 353 ? 149.582 176.651 176.994 1.00 110.45 ? 353 GLU A N   1 
ATOM 2517 C CA  . GLU A 1 353 ? 148.167 176.673 177.344 1.00 111.11 ? 353 GLU A CA  1 
ATOM 2518 C C   . GLU A 1 353 ? 147.366 177.596 176.438 1.00 110.59 ? 353 GLU A C   1 
ATOM 2519 O O   . GLU A 1 353 ? 146.137 177.473 176.377 1.00 104.04 ? 353 GLU A O   1 
ATOM 2520 C CB  . GLU A 1 353 ? 147.996 177.097 178.804 1.00 110.78 ? 353 GLU A CB  1 
ATOM 2521 C CG  . GLU A 1 353 ? 148.366 176.016 179.808 1.00 111.30 ? 353 GLU A CG  1 
ATOM 2522 C CD  . GLU A 1 353 ? 149.863 175.793 179.905 1.00 113.12 ? 353 GLU A CD  1 
ATOM 2523 O OE1 . GLU A 1 353 ? 150.627 176.680 179.469 1.00 113.90 ? 353 GLU A OE1 1 
ATOM 2524 O OE2 . GLU A 1 353 ? 150.275 174.730 180.414 1.00 110.97 ? 353 GLU A OE2 1 
ATOM 2525 N N   . GLY A 1 354 ? 148.028 178.512 175.729 1.00 106.34 ? 354 GLY A N   1 
ATOM 2526 C CA  . GLY A 1 354 ? 147.323 179.398 174.821 1.00 101.95 ? 354 GLY A CA  1 
ATOM 2527 C C   . GLY A 1 354 ? 146.602 178.671 173.707 1.00 102.09 ? 354 GLY A C   1 
ATOM 2528 O O   . GLY A 1 354 ? 145.709 179.247 173.077 1.00 101.60 ? 354 GLY A O   1 
ATOM 2529 N N   . ILE A 1 355 ? 146.969 177.415 173.450 1.00 100.43 ? 355 ILE A N   1 
ATOM 2530 C CA  . ILE A 1 355 ? 146.282 176.631 172.428 1.00 100.42 ? 355 ILE A CA  1 
ATOM 2531 C C   . ILE A 1 355 ? 144.806 176.489 172.773 1.00 103.23 ? 355 ILE A C   1 
ATOM 2532 O O   . ILE A 1 355 ? 143.942 176.498 171.888 1.00 102.86 ? 355 ILE A O   1 
ATOM 2533 C CB  . ILE A 1 355 ? 146.957 175.256 172.273 1.00 100.67 ? 355 ILE A CB  1 
ATOM 2534 C CG1 . ILE A 1 355 ? 148.379 175.413 171.725 1.00 102.80 ? 355 ILE A CG1 1 
ATOM 2535 C CG2 . ILE A 1 355 ? 146.121 174.347 171.382 1.00 101.33 ? 355 ILE A CG2 1 
ATOM 2536 C CD1 . ILE A 1 355 ? 148.445 175.926 170.301 1.00 102.48 ? 355 ILE A CD1 1 
ATOM 2537 N N   . ALA A 1 356 ? 144.493 176.354 174.063 1.00 103.44 ? 356 ALA A N   1 
ATOM 2538 C CA  . ALA A 1 356 ? 143.113 176.116 174.471 1.00 105.94 ? 356 ALA A CA  1 
ATOM 2539 C C   . ALA A 1 356 ? 142.194 177.242 174.016 1.00 106.06 ? 356 ALA A C   1 
ATOM 2540 O O   . ALA A 1 356 ? 141.068 176.994 173.571 1.00 105.92 ? 356 ALA A O   1 
ATOM 2541 C CB  . ALA A 1 356 ? 143.040 175.949 175.989 1.00 105.58 ? 356 ALA A CB  1 
ATOM 2542 N N   . LEU A 1 357 ? 142.656 178.489 174.122 1.00 97.60  ? 357 LEU A N   1 
ATOM 2543 C CA  . LEU A 1 357 ? 141.806 179.624 173.777 1.00 93.67  ? 357 LEU A CA  1 
ATOM 2544 C C   . LEU A 1 357 ? 141.392 179.577 172.311 1.00 97.11  ? 357 LEU A C   1 
ATOM 2545 O O   . LEU A 1 357 ? 140.233 179.837 171.972 1.00 103.45 ? 357 LEU A O   1 
ATOM 2546 C CB  . LEU A 1 357 ? 142.531 180.933 174.088 1.00 95.34  ? 357 LEU A CB  1 
ATOM 2547 C CG  . LEU A 1 357 ? 143.035 181.095 175.523 1.00 100.51 ? 357 LEU A CG  1 
ATOM 2548 C CD1 . LEU A 1 357 ? 143.766 182.419 175.679 1.00 100.83 ? 357 LEU A CD1 1 
ATOM 2549 C CD2 . LEU A 1 357 ? 141.890 180.991 176.518 1.00 95.77  ? 357 LEU A CD2 1 
ATOM 2550 N N   . ILE A 1 358 ? 142.331 179.245 171.425 1.00 93.42  ? 358 ILE A N   1 
ATOM 2551 C CA  . ILE A 1 358 ? 142.034 179.266 169.997 1.00 93.45  ? 358 ILE A CA  1 
ATOM 2552 C C   . ILE A 1 358 ? 141.373 177.965 169.552 1.00 96.51  ? 358 ILE A C   1 
ATOM 2553 O O   . ILE A 1 358 ? 140.778 177.908 168.470 1.00 97.76  ? 358 ILE A O   1 
ATOM 2554 C CB  . ILE A 1 358 ? 143.316 179.539 169.190 1.00 91.61  ? 358 ILE A CB  1 
ATOM 2555 C CG1 . ILE A 1 358 ? 144.135 180.661 169.835 1.00 91.55  ? 358 ILE A CG1 1 
ATOM 2556 C CG2 . ILE A 1 358 ? 142.970 179.905 167.755 1.00 92.16  ? 358 ILE A CG2 1 
ATOM 2557 C CD1 . ILE A 1 358 ? 145.451 180.927 169.145 1.00 95.73  ? 358 ILE A CD1 1 
ATOM 2558 N N   . ALA A 1 359 ? 141.450 176.911 170.367 1.00 102.02 ? 359 ALA A N   1 
ATOM 2559 C CA  . ALA A 1 359 ? 140.971 175.603 169.932 1.00 102.80 ? 359 ALA A CA  1 
ATOM 2560 C C   . ALA A 1 359 ? 139.474 175.605 169.655 1.00 100.08 ? 359 ALA A C   1 
ATOM 2561 O O   . ALA A 1 359 ? 138.982 174.749 168.911 1.00 97.67  ? 359 ALA A O   1 
ATOM 2562 C CB  . ALA A 1 359 ? 141.309 174.548 170.985 1.00 102.97 ? 359 ALA A CB  1 
ATOM 2563 N N   . GLY A 1 360 ? 138.731 176.546 170.239 1.00 85.99  ? 360 GLY A N   1 
ATOM 2564 C CA  . GLY A 1 360 ? 137.288 176.556 170.070 1.00 84.78  ? 360 GLY A CA  1 
ATOM 2565 C C   . GLY A 1 360 ? 136.821 177.083 168.730 1.00 86.17  ? 360 GLY A C   1 
ATOM 2566 O O   . GLY A 1 360 ? 135.664 176.858 168.359 1.00 87.20  ? 360 GLY A O   1 
ATOM 2567 N N   . ILE A 1 361 ? 137.689 177.779 167.996 1.00 87.21  ? 361 ILE A N   1 
ATOM 2568 C CA  . ILE A 1 361 ? 137.315 178.406 166.733 1.00 85.97  ? 361 ILE A CA  1 
ATOM 2569 C C   . ILE A 1 361 ? 138.284 177.987 165.636 1.00 83.44  ? 361 ILE A C   1 
ATOM 2570 O O   . ILE A 1 361 ? 138.513 178.733 164.678 1.00 84.58  ? 361 ILE A O   1 
ATOM 2571 C CB  . ILE A 1 361 ? 137.270 179.937 166.881 1.00 86.65  ? 361 ILE A CB  1 
ATOM 2572 C CG1 . ILE A 1 361 ? 138.672 180.504 167.126 1.00 85.94  ? 361 ILE A CG1 1 
ATOM 2573 C CG2 . ILE A 1 361 ? 136.340 180.330 168.015 1.00 92.77  ? 361 ILE A CG2 1 
ATOM 2574 C CD1 . ILE A 1 361 ? 138.762 181.989 166.925 1.00 85.63  ? 361 ILE A CD1 1 
ATOM 2575 N N   . ASP A 1 362 ? 138.857 176.791 165.765 1.00 92.53  ? 362 ASP A N   1 
ATOM 2576 C CA  . ASP A 1 362 ? 139.930 176.390 164.862 1.00 95.34  ? 362 ASP A CA  1 
ATOM 2577 C C   . ASP A 1 362 ? 139.443 176.268 163.422 1.00 99.28  ? 362 ASP A C   1 
ATOM 2578 O O   . ASP A 1 362 ? 140.153 176.660 162.490 1.00 103.12 ? 362 ASP A O   1 
ATOM 2579 C CB  . ASP A 1 362 ? 140.543 175.072 165.329 1.00 95.10  ? 362 ASP A CB  1 
ATOM 2580 C CG  . ASP A 1 362 ? 141.823 174.739 164.596 1.00 99.14  ? 362 ASP A CG  1 
ATOM 2581 O OD1 . ASP A 1 362 ? 142.835 175.432 164.825 1.00 100.12 ? 362 ASP A OD1 1 
ATOM 2582 O OD2 . ASP A 1 362 ? 141.817 173.786 163.789 1.00 99.77  ? 362 ASP A OD2 1 
ATOM 2583 N N   . ARG A 1 363 ? 138.244 175.717 163.214 1.00 76.09  ? 363 ARG A N   1 
ATOM 2584 C CA  . ARG A 1 363 ? 137.790 175.442 161.853 1.00 77.02  ? 363 ARG A CA  1 
ATOM 2585 C C   . ARG A 1 363 ? 137.633 176.722 161.041 1.00 80.03  ? 363 ARG A C   1 
ATOM 2586 O O   . ARG A 1 363 ? 137.929 176.746 159.838 1.00 83.45  ? 363 ARG A O   1 
ATOM 2587 C CB  . ARG A 1 363 ? 136.472 174.672 161.876 1.00 73.30  ? 363 ARG A CB  1 
ATOM 2588 C CG  . ARG A 1 363 ? 135.927 174.401 160.486 1.00 77.33  ? 363 ARG A CG  1 
ATOM 2589 C CD  . ARG A 1 363 ? 134.786 173.409 160.497 1.00 78.20  ? 363 ARG A CD  1 
ATOM 2590 N NE  . ARG A 1 363 ? 134.380 173.058 159.142 1.00 76.88  ? 363 ARG A NE  1 
ATOM 2591 C CZ  . ARG A 1 363 ? 135.033 172.209 158.360 1.00 72.52  ? 363 ARG A CZ  1 
ATOM 2592 N NH1 . ARG A 1 363 ? 136.131 171.596 158.770 1.00 70.01  ? 363 ARG A NH1 1 
ATOM 2593 N NH2 . ARG A 1 363 ? 134.575 171.972 157.135 1.00 71.74  ? 363 ARG A NH2 1 
ATOM 2594 N N   . ILE A 1 364 ? 137.141 177.788 161.668 1.00 75.87  ? 364 ILE A N   1 
ATOM 2595 C CA  . ILE A 1 364 ? 136.928 179.035 160.941 1.00 75.97  ? 364 ILE A CA  1 
ATOM 2596 C C   . ILE A 1 364 ? 138.251 179.565 160.408 1.00 81.08  ? 364 ILE A C   1 
ATOM 2597 O O   . ILE A 1 364 ? 138.335 180.055 159.276 1.00 83.36  ? 364 ILE A O   1 
ATOM 2598 C CB  . ILE A 1 364 ? 136.222 180.061 161.841 1.00 75.72  ? 364 ILE A CB  1 
ATOM 2599 C CG1 . ILE A 1 364 ? 134.875 179.499 162.288 1.00 81.69  ? 364 ILE A CG1 1 
ATOM 2600 C CG2 . ILE A 1 364 ? 136.041 181.382 161.109 1.00 75.96  ? 364 ILE A CG2 1 
ATOM 2601 C CD1 . ILE A 1 364 ? 134.171 180.354 163.272 1.00 81.62  ? 364 ILE A CD1 1 
ATOM 2602 N N   . LEU A 1 365 ? 139.304 179.484 161.221 1.00 82.02  ? 365 LEU A N   1 
ATOM 2603 C CA  . LEU A 1 365 ? 140.625 179.871 160.740 1.00 77.49  ? 365 LEU A CA  1 
ATOM 2604 C C   . LEU A 1 365 ? 141.122 178.905 159.673 1.00 80.41  ? 365 LEU A C   1 
ATOM 2605 O O   . LEU A 1 365 ? 141.698 179.331 158.664 1.00 87.27  ? 365 LEU A O   1 
ATOM 2606 C CB  . LEU A 1 365 ? 141.607 179.944 161.908 1.00 77.37  ? 365 LEU A CB  1 
ATOM 2607 C CG  . LEU A 1 365 ? 141.103 180.696 163.143 1.00 78.40  ? 365 LEU A CG  1 
ATOM 2608 C CD1 . LEU A 1 365 ? 142.134 180.655 164.253 1.00 79.26  ? 365 LEU A CD1 1 
ATOM 2609 C CD2 . LEU A 1 365 ? 140.755 182.130 162.792 1.00 78.10  ? 365 LEU A CD2 1 
ATOM 2610 N N   . ASP A 1 366 ? 140.892 177.603 159.871 1.00 73.96  ? 366 ASP A N   1 
ATOM 2611 C CA  . ASP A 1 366 ? 141.326 176.608 158.896 1.00 75.92  ? 366 ASP A CA  1 
ATOM 2612 C C   . ASP A 1 366 ? 140.752 176.899 157.519 1.00 79.00  ? 366 ASP A C   1 
ATOM 2613 O O   . ASP A 1 366 ? 141.398 176.634 156.499 1.00 79.50  ? 366 ASP A O   1 
ATOM 2614 C CB  . ASP A 1 366 ? 140.911 175.209 159.351 1.00 78.61  ? 366 ASP A CB  1 
ATOM 2615 C CG  . ASP A 1 366 ? 142.027 174.191 159.210 1.00 89.09  ? 366 ASP A CG  1 
ATOM 2616 O OD1 . ASP A 1 366 ? 141.998 173.175 159.934 1.00 88.18  ? 366 ASP A OD1 1 
ATOM 2617 O OD2 . ASP A 1 366 ? 142.928 174.400 158.370 1.00 86.83  ? 366 ASP A OD2 1 
ATOM 2618 N N   . MET A 1 367 ? 139.529 177.422 157.468 1.00 75.57  ? 367 MET A N   1 
ATOM 2619 C CA  . MET A 1 367 ? 138.924 177.730 156.177 1.00 73.34  ? 367 MET A CA  1 
ATOM 2620 C C   . MET A 1 367 ? 139.817 178.673 155.378 1.00 67.70  ? 367 MET A C   1 
ATOM 2621 O O   . MET A 1 367 ? 140.209 178.374 154.240 1.00 69.88  ? 367 MET A O   1 
ATOM 2622 C CB  . MET A 1 367 ? 137.546 178.354 156.387 1.00 73.88  ? 367 MET A CB  1 
ATOM 2623 C CG  . MET A 1 367 ? 136.479 177.367 156.816 1.00 71.49  ? 367 MET A CG  1 
ATOM 2624 S SD  . MET A 1 367 ? 135.102 178.148 157.676 1.00 89.63  ? 367 MET A SD  1 
ATOM 2625 C CE  . MET A 1 367 ? 133.717 177.483 156.759 1.00 74.86  ? 367 MET A CE  1 
ATOM 2626 N N   . ALA A 1 368 ? 140.184 179.805 155.982 1.00 70.77  ? 368 ALA A N   1 
ATOM 2627 C CA  . ALA A 1 368 ? 141.041 180.769 155.301 1.00 78.35  ? 368 ALA A CA  1 
ATOM 2628 C C   . ALA A 1 368 ? 142.434 180.201 155.071 1.00 81.45  ? 368 ALA A C   1 
ATOM 2629 O O   . ALA A 1 368 ? 143.058 180.476 154.039 1.00 85.10  ? 368 ALA A O   1 
ATOM 2630 C CB  . ALA A 1 368 ? 141.116 182.063 156.109 1.00 72.99  ? 368 ALA A CB  1 
ATOM 2631 N N   . ARG A 1 369 ? 142.945 179.419 156.023 1.00 78.67  ? 369 ARG A N   1 
ATOM 2632 C CA  . ARG A 1 369 ? 144.265 178.825 155.856 1.00 76.70  ? 369 ARG A CA  1 
ATOM 2633 C C   . ARG A 1 369 ? 144.322 177.994 154.581 1.00 81.19  ? 369 ARG A C   1 
ATOM 2634 O O   . ARG A 1 369 ? 145.215 178.166 153.745 1.00 88.23  ? 369 ARG A O   1 
ATOM 2635 C CB  . ARG A 1 369 ? 144.613 177.968 157.074 1.00 83.02  ? 369 ARG A CB  1 
ATOM 2636 C CG  . ARG A 1 369 ? 144.793 178.760 158.352 1.00 78.98  ? 369 ARG A CG  1 
ATOM 2637 C CD  . ARG A 1 369 ? 145.490 177.954 159.431 1.00 78.82  ? 369 ARG A CD  1 
ATOM 2638 N NE  . ARG A 1 369 ? 144.717 176.806 159.894 1.00 78.59  ? 369 ARG A NE  1 
ATOM 2639 C CZ  . ARG A 1 369 ? 144.180 176.690 161.102 1.00 85.78  ? 369 ARG A CZ  1 
ATOM 2640 N NH1 . ARG A 1 369 ? 144.199 177.688 161.971 1.00 88.10  ? 369 ARG A NH1 1 
ATOM 2641 N NH2 . ARG A 1 369 ? 143.599 175.546 161.446 1.00 84.52  ? 369 ARG A NH2 1 
ATOM 2642 N N   . THR A 1 370 ? 143.352 177.095 154.409 1.00 70.73  ? 370 THR A N   1 
ATOM 2643 C CA  . THR A 1 370 ? 143.343 176.237 153.230 1.00 71.52  ? 370 THR A CA  1 
ATOM 2644 C C   . THR A 1 370 ? 143.059 177.028 151.961 1.00 74.20  ? 370 THR A C   1 
ATOM 2645 O O   . THR A 1 370 ? 143.628 176.722 150.903 1.00 80.39  ? 370 THR A O   1 
ATOM 2646 C CB  . THR A 1 370 ? 142.317 175.117 153.394 1.00 73.75  ? 370 THR A CB  1 
ATOM 2647 O OG1 . THR A 1 370 ? 140.994 175.656 153.291 1.00 83.52  ? 370 THR A OG1 1 
ATOM 2648 C CG2 . THR A 1 370 ? 142.490 174.419 154.734 1.00 75.79  ? 370 THR A CG2 1 
ATOM 2649 N N   . THR A 1 371 ? 142.185 178.035 152.032 1.00 72.05  ? 371 THR A N   1 
ATOM 2650 C CA  . THR A 1 371 ? 141.950 178.862 150.854 1.00 71.03  ? 371 THR A CA  1 
ATOM 2651 C C   . THR A 1 371 ? 143.244 179.510 150.383 1.00 68.02  ? 371 THR A C   1 
ATOM 2652 O O   . THR A 1 371 ? 143.583 179.458 149.192 1.00 74.88  ? 371 THR A O   1 
ATOM 2653 C CB  . THR A 1 371 ? 140.900 179.927 151.163 1.00 67.40  ? 371 THR A CB  1 
ATOM 2654 O OG1 . THR A 1 371 ? 139.605 179.318 151.230 1.00 73.57  ? 371 THR A OG1 1 
ATOM 2655 C CG2 . THR A 1 371 ? 140.894 181.002 150.090 1.00 70.30  ? 371 THR A CG2 1 
ATOM 2656 N N   . VAL A 1 372 ? 143.993 180.106 151.311 1.00 64.31  ? 372 VAL A N   1 
ATOM 2657 C CA  . VAL A 1 372 ? 145.249 180.750 150.948 1.00 69.04  ? 372 VAL A CA  1 
ATOM 2658 C C   . VAL A 1 372 ? 146.252 179.720 150.451 1.00 67.75  ? 372 VAL A C   1 
ATOM 2659 O O   . VAL A 1 372 ? 147.027 179.990 149.530 1.00 71.17  ? 372 VAL A O   1 
ATOM 2660 C CB  . VAL A 1 372 ? 145.804 181.547 152.140 1.00 72.47  ? 372 VAL A CB  1 
ATOM 2661 C CG1 . VAL A 1 372 ? 147.222 182.006 151.855 1.00 71.03  ? 372 VAL A CG1 1 
ATOM 2662 C CG2 . VAL A 1 372 ? 144.910 182.732 152.439 1.00 70.12  ? 372 VAL A CG2 1 
ATOM 2663 N N   . ASN A 1 373 ? 146.260 178.527 151.047 1.00 63.90  ? 373 ASN A N   1 
ATOM 2664 C CA  . ASN A 1 373 ? 147.190 177.492 150.609 1.00 64.52  ? 373 ASN A CA  1 
ATOM 2665 C C   . ASN A 1 373 ? 146.947 177.121 149.150 1.00 74.69  ? 373 ASN A C   1 
ATOM 2666 O O   . ASN A 1 373 ? 147.878 177.100 148.335 1.00 88.29  ? 373 ASN A O   1 
ATOM 2667 C CB  . ASN A 1 373 ? 147.058 176.262 151.507 1.00 72.69  ? 373 ASN A CB  1 
ATOM 2668 C CG  . ASN A 1 373 ? 147.400 176.557 152.952 1.00 76.13  ? 373 ASN A CG  1 
ATOM 2669 O OD1 . ASN A 1 373 ? 148.019 177.574 153.259 1.00 74.27  ? 373 ASN A OD1 1 
ATOM 2670 N ND2 . ASN A 1 373 ? 146.995 175.668 153.849 1.00 72.86  ? 373 ASN A ND2 1 
ATOM 2671 N N   . VAL A 1 374 ? 145.692 176.827 148.800 1.00 62.96  ? 374 VAL A N   1 
ATOM 2672 C CA  . VAL A 1 374 ? 145.392 176.423 147.427 1.00 63.43  ? 374 VAL A CA  1 
ATOM 2673 C C   . VAL A 1 374 ? 145.656 177.575 146.463 1.00 69.29  ? 374 VAL A C   1 
ATOM 2674 O O   . VAL A 1 374 ? 146.191 177.376 145.359 1.00 72.39  ? 374 VAL A O   1 
ATOM 2675 C CB  . VAL A 1 374 ? 143.947 175.899 147.318 1.00 65.70  ? 374 VAL A CB  1 
ATOM 2676 C CG1 . VAL A 1 374 ? 143.755 174.703 148.232 1.00 69.18  ? 374 VAL A CG1 1 
ATOM 2677 C CG2 . VAL A 1 374 ? 142.937 176.984 147.651 1.00 72.67  ? 374 VAL A CG2 1 
ATOM 2678 N N   . THR A 1 375 ? 145.291 178.797 146.858 1.00 67.20  ? 375 THR A N   1 
ATOM 2679 C CA  . THR A 1 375 ? 145.581 179.945 146.009 1.00 59.33  ? 375 THR A CA  1 
ATOM 2680 C C   . THR A 1 375 ? 147.077 180.070 145.764 1.00 59.18  ? 375 THR A C   1 
ATOM 2681 O O   . THR A 1 375 ? 147.507 180.344 144.638 1.00 67.38  ? 375 THR A O   1 
ATOM 2682 C CB  . THR A 1 375 ? 145.032 181.219 146.647 1.00 67.54  ? 375 THR A CB  1 
ATOM 2683 O OG1 . THR A 1 375 ? 143.638 181.049 146.930 1.00 72.61  ? 375 THR A OG1 1 
ATOM 2684 C CG2 . THR A 1 375 ? 145.217 182.407 145.719 1.00 71.22  ? 375 THR A CG2 1 
ATOM 2685 N N   . GLY A 1 376 ? 147.884 179.869 146.805 1.00 58.88  ? 376 GLY A N   1 
ATOM 2686 C CA  . GLY A 1 376 ? 149.322 179.952 146.641 1.00 57.04  ? 376 GLY A CA  1 
ATOM 2687 C C   . GLY A 1 376 ? 149.861 178.874 145.727 1.00 61.20  ? 376 GLY A C   1 
ATOM 2688 O O   . GLY A 1 376 ? 150.773 179.119 144.937 1.00 67.85  ? 376 GLY A O   1 
ATOM 2689 N N   . ASP A 1 377 ? 149.312 177.663 145.824 1.00 66.89  ? 377 ASP A N   1 
ATOM 2690 C CA  . ASP A 1 377 ? 149.748 176.600 144.923 1.00 68.93  ? 377 ASP A CA  1 
ATOM 2691 C C   . ASP A 1 377 ? 149.482 176.979 143.473 1.00 69.40  ? 377 ASP A C   1 
ATOM 2692 O O   . ASP A 1 377 ? 150.354 176.838 142.604 1.00 64.41  ? 377 ASP A O   1 
ATOM 2693 C CB  . ASP A 1 377 ? 149.046 175.286 145.264 1.00 69.48  ? 377 ASP A CB  1 
ATOM 2694 C CG  . ASP A 1 377 ? 149.232 174.884 146.704 1.00 71.90  ? 377 ASP A CG  1 
ATOM 2695 O OD1 . ASP A 1 377 ? 148.240 174.880 147.458 1.00 72.65  ? 377 ASP A OD1 1 
ATOM 2696 O OD2 . ASP A 1 377 ? 150.380 174.597 147.090 1.00 74.48  ? 377 ASP A OD2 1 
ATOM 2697 N N   . LEU A 1 378 ? 148.276 177.474 143.193 1.00 69.74  ? 378 LEU A N   1 
ATOM 2698 C CA  . LEU A 1 378 ? 147.954 177.853 141.821 1.00 61.89  ? 378 LEU A CA  1 
ATOM 2699 C C   . LEU A 1 378 ? 148.811 179.022 141.344 1.00 67.61  ? 378 LEU A C   1 
ATOM 2700 O O   . LEU A 1 378 ? 149.242 179.043 140.184 1.00 69.52  ? 378 LEU A O   1 
ATOM 2701 C CB  . LEU A 1 378 ? 146.469 178.184 141.708 1.00 61.03  ? 378 LEU A CB  1 
ATOM 2702 C CG  . LEU A 1 378 ? 145.585 176.944 141.567 1.00 58.72  ? 378 LEU A CG  1 
ATOM 2703 C CD1 . LEU A 1 378 ? 144.211 177.187 142.158 1.00 59.99  ? 378 LEU A CD1 1 
ATOM 2704 C CD2 . LEU A 1 378 ? 145.478 176.536 140.111 1.00 60.86  ? 378 LEU A CD2 1 
ATOM 2705 N N   . VAL A 1 379 ? 149.077 179.995 142.217 1.00 73.88  ? 379 VAL A N   1 
ATOM 2706 C CA  . VAL A 1 379 ? 149.922 181.122 141.833 1.00 65.23  ? 379 VAL A CA  1 
ATOM 2707 C C   . VAL A 1 379 ? 151.343 180.653 141.545 1.00 64.89  ? 379 VAL A C   1 
ATOM 2708 O O   . VAL A 1 379 ? 151.993 181.136 140.611 1.00 71.20  ? 379 VAL A O   1 
ATOM 2709 C CB  . VAL A 1 379 ? 149.891 182.204 142.926 1.00 58.43  ? 379 VAL A CB  1 
ATOM 2710 C CG1 . VAL A 1 379 ? 150.960 183.249 142.667 1.00 64.88  ? 379 VAL A CG1 1 
ATOM 2711 C CG2 . VAL A 1 379 ? 148.522 182.850 142.983 1.00 64.62  ? 379 VAL A CG2 1 
ATOM 2712 N N   . ALA A 1 380 ? 151.856 179.722 142.351 1.00 60.40  ? 380 ALA A N   1 
ATOM 2713 C CA  . ALA A 1 380 ? 153.181 179.169 142.097 1.00 62.79  ? 380 ALA A CA  1 
ATOM 2714 C C   . ALA A 1 380 ? 153.223 178.481 140.744 1.00 66.56  ? 380 ALA A C   1 
ATOM 2715 O O   . ALA A 1 380 ? 154.190 178.623 139.986 1.00 65.91  ? 380 ALA A O   1 
ATOM 2716 C CB  . ALA A 1 380 ? 153.555 178.182 143.201 1.00 61.87  ? 380 ALA A CB  1 
ATOM 2717 N N   . THR A 1 381 ? 152.179 177.710 140.432 1.00 73.86  ? 381 THR A N   1 
ATOM 2718 C CA  . THR A 1 381 ? 152.117 177.059 139.129 1.00 66.56  ? 381 THR A CA  1 
ATOM 2719 C C   . THR A 1 381 ? 152.143 178.088 138.011 1.00 64.70  ? 381 THR A C   1 
ATOM 2720 O O   . THR A 1 381 ? 152.874 177.930 137.025 1.00 68.17  ? 381 THR A O   1 
ATOM 2721 C CB  . THR A 1 381 ? 150.859 176.201 139.031 1.00 66.31  ? 381 THR A CB  1 
ATOM 2722 O OG1 . THR A 1 381 ? 150.897 175.186 140.040 1.00 74.66  ? 381 THR A OG1 1 
ATOM 2723 C CG2 . THR A 1 381 ? 150.758 175.551 137.662 1.00 70.17  ? 381 THR A CG2 1 
ATOM 2724 N N   . ALA A 1 382 ? 151.361 179.158 138.151 1.00 65.88  ? 382 ALA A N   1 
ATOM 2725 C CA  . ALA A 1 382 ? 151.355 180.196 137.127 1.00 61.49  ? 382 ALA A CA  1 
ATOM 2726 C C   . ALA A 1 382 ? 152.739 180.809 136.964 1.00 59.22  ? 382 ALA A C   1 
ATOM 2727 O O   . ALA A 1 382 ? 153.213 181.000 135.839 1.00 63.62  ? 382 ALA A O   1 
ATOM 2728 C CB  . ALA A 1 382 ? 150.332 181.273 137.477 1.00 69.32  ? 382 ALA A CB  1 
ATOM 2729 N N   . ILE A 1 383 ? 153.409 181.107 138.078 1.00 71.23  ? 383 ILE A N   1 
ATOM 2730 C CA  . ILE A 1 383 ? 154.719 181.754 138.012 1.00 72.22  ? 383 ILE A CA  1 
ATOM 2731 C C   . ILE A 1 383 ? 155.719 180.852 137.302 1.00 75.89  ? 383 ILE A C   1 
ATOM 2732 O O   . ILE A 1 383 ? 156.422 181.278 136.378 1.00 82.50  ? 383 ILE A O   1 
ATOM 2733 C CB  . ILE A 1 383 ? 155.210 182.130 139.421 1.00 73.87  ? 383 ILE A CB  1 
ATOM 2734 C CG1 . ILE A 1 383 ? 154.577 183.453 139.858 1.00 73.77  ? 383 ILE A CG1 1 
ATOM 2735 C CG2 . ILE A 1 383 ? 156.739 182.213 139.446 1.00 72.24  ? 383 ILE A CG2 1 
ATOM 2736 C CD1 . ILE A 1 383 ? 155.035 183.958 141.202 1.00 71.76  ? 383 ILE A CD1 1 
ATOM 2737 N N   . VAL A 1 384 ? 155.807 179.590 137.728 1.00 72.27  ? 384 VAL A N   1 
ATOM 2738 C CA  . VAL A 1 384 ? 156.823 178.709 137.156 1.00 68.02  ? 384 VAL A CA  1 
ATOM 2739 C C   . VAL A 1 384 ? 156.519 178.432 135.690 1.00 70.18  ? 384 VAL A C   1 
ATOM 2740 O O   . VAL A 1 384 ? 157.432 178.340 134.862 1.00 71.30  ? 384 VAL A O   1 
ATOM 2741 C CB  . VAL A 1 384 ? 156.951 177.405 137.966 1.00 70.97  ? 384 VAL A CB  1 
ATOM 2742 C CG1 . VAL A 1 384 ? 157.671 177.670 139.277 1.00 71.96  ? 384 VAL A CG1 1 
ATOM 2743 C CG2 . VAL A 1 384 ? 155.597 176.757 138.203 1.00 75.89  ? 384 VAL A CG2 1 
ATOM 2744 N N   . ALA A 1 385 ? 155.238 178.295 135.340 1.00 75.27  ? 385 ALA A N   1 
ATOM 2745 C CA  . ALA A 1 385 ? 154.887 178.092 133.940 1.00 73.27  ? 385 ALA A CA  1 
ATOM 2746 C C   . ALA A 1 385 ? 155.272 179.299 133.097 1.00 78.21  ? 385 ALA A C   1 
ATOM 2747 O O   . ALA A 1 385 ? 155.806 179.150 131.992 1.00 77.74  ? 385 ALA A O   1 
ATOM 2748 C CB  . ALA A 1 385 ? 153.393 177.804 133.810 1.00 72.29  ? 385 ALA A CB  1 
ATOM 2749 N N   . ARG A 1 386 ? 155.012 180.507 133.601 1.00 87.64  ? 386 ARG A N   1 
ATOM 2750 C CA  . ARG A 1 386 ? 155.293 181.705 132.818 1.00 85.37  ? 386 ARG A CA  1 
ATOM 2751 C C   . ARG A 1 386 ? 156.790 181.946 132.692 1.00 81.97  ? 386 ARG A C   1 
ATOM 2752 O O   . ARG A 1 386 ? 157.256 182.464 131.671 1.00 85.36  ? 386 ARG A O   1 
ATOM 2753 C CB  . ARG A 1 386 ? 154.612 182.916 133.452 1.00 85.18  ? 386 ARG A CB  1 
ATOM 2754 C CG  . ARG A 1 386 ? 154.022 183.895 132.441 1.00 87.55  ? 386 ARG A CG  1 
ATOM 2755 C CD  . ARG A 1 386 ? 155.076 184.789 131.793 1.00 90.70  ? 386 ARG A CD  1 
ATOM 2756 N NE  . ARG A 1 386 ? 156.027 185.337 132.754 1.00 93.80  ? 386 ARG A NE  1 
ATOM 2757 C CZ  . ARG A 1 386 ? 157.250 185.751 132.451 1.00 92.21  ? 386 ARG A CZ  1 
ATOM 2758 N NH1 . ARG A 1 386 ? 157.711 185.706 131.211 1.00 89.70  ? 386 ARG A NH1 1 
ATOM 2759 N NH2 . ARG A 1 386 ? 158.031 186.224 133.417 1.00 86.16  ? 386 ARG A NH2 1 
ATOM 2760 N N   . THR A 1 387 ? 157.560 181.579 133.717 1.00 79.96  ? 387 THR A N   1 
ATOM 2761 C CA  . THR A 1 387 ? 158.981 181.912 133.719 1.00 82.70  ? 387 THR A CA  1 
ATOM 2762 C C   . THR A 1 387 ? 159.696 181.300 132.523 1.00 82.36  ? 387 THR A C   1 
ATOM 2763 O O   . THR A 1 387 ? 160.617 181.909 131.966 1.00 80.33  ? 387 THR A O   1 
ATOM 2764 C CB  . THR A 1 387 ? 159.633 181.447 135.020 1.00 81.71  ? 387 THR A CB  1 
ATOM 2765 O OG1 . THR A 1 387 ? 158.939 182.017 136.137 1.00 83.09  ? 387 THR A OG1 1 
ATOM 2766 C CG2 . THR A 1 387 ? 161.086 181.884 135.065 1.00 77.57  ? 387 THR A CG2 1 
ATOM 2767 N N   . GLU A 1 388 ? 159.293 180.099 132.112 1.00 85.71  ? 388 GLU A N   1 
ATOM 2768 C CA  . GLU A 1 388 ? 159.945 179.397 131.016 1.00 86.19  ? 388 GLU A CA  1 
ATOM 2769 C C   . GLU A 1 388 ? 159.188 179.521 129.700 1.00 88.58  ? 388 GLU A C   1 
ATOM 2770 O O   . GLU A 1 388 ? 159.651 178.996 128.682 1.00 86.63  ? 388 GLU A O   1 
ATOM 2771 C CB  . GLU A 1 388 ? 160.121 177.921 131.376 1.00 84.73  ? 388 GLU A CB  1 
ATOM 2772 C CG  . GLU A 1 388 ? 160.399 177.669 132.847 1.00 84.54  ? 388 GLU A CG  1 
ATOM 2773 C CD  . GLU A 1 388 ? 161.324 176.492 133.072 1.00 84.91  ? 388 GLU A CD  1 
ATOM 2774 O OE1 . GLU A 1 388 ? 162.542 176.634 132.835 1.00 86.32  ? 388 GLU A OE1 1 
ATOM 2775 O OE2 . GLU A 1 388 ? 160.834 175.422 133.481 1.00 85.07  ? 388 GLU A OE2 1 
ATOM 2776 N N   . ASN A 1 389 ? 158.054 180.214 129.687 1.00 98.44  ? 389 ASN A N   1 
ATOM 2777 C CA  . ASN A 1 389 ? 157.299 180.414 128.453 1.00 97.44  ? 389 ASN A CA  1 
ATOM 2778 C C   . ASN A 1 389 ? 156.761 181.839 128.389 1.00 97.14  ? 389 ASN A C   1 
ATOM 2779 O O   . ASN A 1 389 ? 155.570 182.054 128.164 1.00 97.44  ? 389 ASN A O   1 
ATOM 2780 C CB  . ASN A 1 389 ? 156.142 179.416 128.345 1.00 96.39  ? 389 ASN A CB  1 
ATOM 2781 C CG  . ASN A 1 389 ? 156.495 178.042 128.884 1.00 97.14  ? 389 ASN A CG  1 
ATOM 2782 O OD1 . ASN A 1 389 ? 157.484 177.442 128.467 1.00 96.61  ? 389 ASN A OD1 1 
ATOM 2783 N ND2 . ASN A 1 389 ? 155.696 177.541 129.817 1.00 95.75  ? 389 ASN A ND2 1 
# 
