data_9BGV
# 
_entry.id   9BGV 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BGV         pdb_00009bgv 10.2210/pdb9bgv/pdb 
WWPDB D_1000282733 ?            ?                   
EMDB  EMD-44524    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-20 
2 'Structure model' 1 1 2024-11-27 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation 
2 2 'Structure model' em_admin 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.page_last'               
2 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
3 2 'Structure model' '_citation.title'                   
4 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BGV 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-19 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'DosP R97A straight form' 
_pdbx_database_related.db_id          EMD-44524 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              daniel.kober@utsouthwestern.edu 
_pdbx_contact_author.name_first         Daniel 
_pdbx_contact_author.name_last          Kober 
_pdbx_contact_author.name_mi            L 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-8657-9348 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kumar, P.'   1 0000-0002-7025-5530 
'Kober, D.L.' 2 0000-0001-8657-9348 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                9653 
_citation.page_last                 9653 
_citation.title                     
'Structures of the multi-domain oxygen sensor DosP: remote control of a c-di-GMP phosphodiesterase by a regulatory PAS domain.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-53942-7 
_citation.pdbx_database_id_PubMed   39511182 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Wu, W.'                1 ? 
primary 'Kumar, P.'             2 ? 
primary 'Brautigam, C.A.'       3 ? 
primary 'Tso, S.C.'             4 ? 
primary 'Baniasadi, H.R.'       5 ? 
primary 'Kober, D.L.'           6 ? 
primary 'Gilles-Gonzalez, M.A.' 7 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Oxygen sensor protein DosP'      91181.156 2 3.1.4.52 R97A ? ? 
2 non-polymer syn 'PROTOPORPHYRIN IX CONTAINING FE' 616.487   2 ?        ?    ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        
'Direct oxygen-sensing phosphodiesterase,Direct oxygen sensor protein,Ec DOS,Heme-regulated cyclic di-GMP phosphodiesterase' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MRQDAEVIMKLTDADSAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEY
IRHNREGGKARVEGMSAELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVL
DPERHIVQCNRAFTEMFGYCISEASGMQPDTLLNTPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVY
DVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAE
IQNAQSWSATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIAD
ELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAI
SNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPAL
SVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSL
PVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMS
SVLPLKI
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MRQDAEVIMKLTDADSAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEY
IRHNREGGKARVEGMSAELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVL
DPERHIVQCNRAFTEMFGYCISEASGMQPDTLLNTPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVY
DVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAE
IQNAQSWSATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIAD
ELRNVVSKPIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAI
SNNQLKLVYQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPAL
SVNLSALHFRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSL
PVTEIKIDKSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMS
SVLPLKI
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        'PROTOPORPHYRIN IX CONTAINING FE' 
_pdbx_entity_nonpoly.comp_id     HEM 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ARG n 
1 3   GLN n 
1 4   ASP n 
1 5   ALA n 
1 6   GLU n 
1 7   VAL n 
1 8   ILE n 
1 9   MET n 
1 10  LYS n 
1 11  LEU n 
1 12  THR n 
1 13  ASP n 
1 14  ALA n 
1 15  ASP n 
1 16  SER n 
1 17  ALA n 
1 18  ALA n 
1 19  ASP n 
1 20  GLY n 
1 21  ILE n 
1 22  PHE n 
1 23  PHE n 
1 24  PRO n 
1 25  ALA n 
1 26  LEU n 
1 27  GLU n 
1 28  GLN n 
1 29  ASN n 
1 30  MET n 
1 31  MET n 
1 32  GLY n 
1 33  ALA n 
1 34  VAL n 
1 35  LEU n 
1 36  ILE n 
1 37  ASN n 
1 38  GLU n 
1 39  ASN n 
1 40  ASP n 
1 41  GLU n 
1 42  VAL n 
1 43  MET n 
1 44  PHE n 
1 45  PHE n 
1 46  ASN n 
1 47  PRO n 
1 48  ALA n 
1 49  ALA n 
1 50  GLU n 
1 51  LYS n 
1 52  LEU n 
1 53  TRP n 
1 54  GLY n 
1 55  TYR n 
1 56  LYS n 
1 57  ARG n 
1 58  GLU n 
1 59  GLU n 
1 60  VAL n 
1 61  ILE n 
1 62  GLY n 
1 63  ASN n 
1 64  ASN n 
1 65  ILE n 
1 66  ASP n 
1 67  MET n 
1 68  LEU n 
1 69  ILE n 
1 70  PRO n 
1 71  ARG n 
1 72  ASP n 
1 73  LEU n 
1 74  ARG n 
1 75  PRO n 
1 76  ALA n 
1 77  HIS n 
1 78  PRO n 
1 79  GLU n 
1 80  TYR n 
1 81  ILE n 
1 82  ARG n 
1 83  HIS n 
1 84  ASN n 
1 85  ARG n 
1 86  GLU n 
1 87  GLY n 
1 88  GLY n 
1 89  LYS n 
1 90  ALA n 
1 91  ARG n 
1 92  VAL n 
1 93  GLU n 
1 94  GLY n 
1 95  MET n 
1 96  SER n 
1 97  ALA n 
1 98  GLU n 
1 99  LEU n 
1 100 GLN n 
1 101 LEU n 
1 102 GLU n 
1 103 LYS n 
1 104 LYS n 
1 105 ASP n 
1 106 GLY n 
1 107 SER n 
1 108 LYS n 
1 109 ILE n 
1 110 TRP n 
1 111 THR n 
1 112 ARG n 
1 113 PHE n 
1 114 ALA n 
1 115 LEU n 
1 116 SER n 
1 117 LYS n 
1 118 VAL n 
1 119 SER n 
1 120 ALA n 
1 121 GLU n 
1 122 GLY n 
1 123 LYS n 
1 124 VAL n 
1 125 TYR n 
1 126 TYR n 
1 127 LEU n 
1 128 ALA n 
1 129 LEU n 
1 130 VAL n 
1 131 ARG n 
1 132 ASP n 
1 133 ALA n 
1 134 SER n 
1 135 VAL n 
1 136 GLU n 
1 137 MET n 
1 138 ALA n 
1 139 GLN n 
1 140 LYS n 
1 141 GLU n 
1 142 GLN n 
1 143 THR n 
1 144 ARG n 
1 145 GLN n 
1 146 LEU n 
1 147 ILE n 
1 148 ILE n 
1 149 ALA n 
1 150 VAL n 
1 151 ASP n 
1 152 HIS n 
1 153 LEU n 
1 154 ASP n 
1 155 ARG n 
1 156 PRO n 
1 157 VAL n 
1 158 ILE n 
1 159 VAL n 
1 160 LEU n 
1 161 ASP n 
1 162 PRO n 
1 163 GLU n 
1 164 ARG n 
1 165 HIS n 
1 166 ILE n 
1 167 VAL n 
1 168 GLN n 
1 169 CYS n 
1 170 ASN n 
1 171 ARG n 
1 172 ALA n 
1 173 PHE n 
1 174 THR n 
1 175 GLU n 
1 176 MET n 
1 177 PHE n 
1 178 GLY n 
1 179 TYR n 
1 180 CYS n 
1 181 ILE n 
1 182 SER n 
1 183 GLU n 
1 184 ALA n 
1 185 SER n 
1 186 GLY n 
1 187 MET n 
1 188 GLN n 
1 189 PRO n 
1 190 ASP n 
1 191 THR n 
1 192 LEU n 
1 193 LEU n 
1 194 ASN n 
1 195 THR n 
1 196 PRO n 
1 197 GLU n 
1 198 PHE n 
1 199 PRO n 
1 200 ALA n 
1 201 ASP n 
1 202 ASN n 
1 203 ARG n 
1 204 ILE n 
1 205 ARG n 
1 206 LEU n 
1 207 GLN n 
1 208 GLN n 
1 209 LEU n 
1 210 LEU n 
1 211 TRP n 
1 212 LYS n 
1 213 THR n 
1 214 ALA n 
1 215 ARG n 
1 216 ASP n 
1 217 GLN n 
1 218 ASP n 
1 219 GLU n 
1 220 PHE n 
1 221 LEU n 
1 222 LEU n 
1 223 LEU n 
1 224 THR n 
1 225 ARG n 
1 226 THR n 
1 227 GLY n 
1 228 GLU n 
1 229 LYS n 
1 230 ILE n 
1 231 TRP n 
1 232 ILE n 
1 233 LYS n 
1 234 ALA n 
1 235 SER n 
1 236 ILE n 
1 237 SER n 
1 238 PRO n 
1 239 VAL n 
1 240 TYR n 
1 241 ASP n 
1 242 VAL n 
1 243 LEU n 
1 244 ALA n 
1 245 HIS n 
1 246 LEU n 
1 247 GLN n 
1 248 ASN n 
1 249 LEU n 
1 250 VAL n 
1 251 MET n 
1 252 THR n 
1 253 PHE n 
1 254 SER n 
1 255 ASP n 
1 256 ILE n 
1 257 THR n 
1 258 GLU n 
1 259 GLU n 
1 260 ARG n 
1 261 GLN n 
1 262 ILE n 
1 263 ARG n 
1 264 GLN n 
1 265 LEU n 
1 266 GLU n 
1 267 GLY n 
1 268 ASN n 
1 269 ILE n 
1 270 LEU n 
1 271 ALA n 
1 272 ALA n 
1 273 MET n 
1 274 CYS n 
1 275 SER n 
1 276 SER n 
1 277 PRO n 
1 278 PRO n 
1 279 PHE n 
1 280 HIS n 
1 281 GLU n 
1 282 MET n 
1 283 GLY n 
1 284 GLU n 
1 285 ILE n 
1 286 ILE n 
1 287 CYS n 
1 288 ARG n 
1 289 ASN n 
1 290 ILE n 
1 291 GLU n 
1 292 SER n 
1 293 VAL n 
1 294 LEU n 
1 295 ASN n 
1 296 GLU n 
1 297 SER n 
1 298 HIS n 
1 299 VAL n 
1 300 SER n 
1 301 LEU n 
1 302 PHE n 
1 303 ALA n 
1 304 LEU n 
1 305 ARG n 
1 306 ASN n 
1 307 GLY n 
1 308 MET n 
1 309 PRO n 
1 310 ILE n 
1 311 HIS n 
1 312 TRP n 
1 313 ALA n 
1 314 SER n 
1 315 SER n 
1 316 SER n 
1 317 HIS n 
1 318 GLY n 
1 319 ALA n 
1 320 GLU n 
1 321 ILE n 
1 322 GLN n 
1 323 ASN n 
1 324 ALA n 
1 325 GLN n 
1 326 SER n 
1 327 TRP n 
1 328 SER n 
1 329 ALA n 
1 330 THR n 
1 331 ILE n 
1 332 ARG n 
1 333 GLN n 
1 334 ARG n 
1 335 ASP n 
1 336 GLY n 
1 337 ALA n 
1 338 PRO n 
1 339 ALA n 
1 340 GLY n 
1 341 ILE n 
1 342 LEU n 
1 343 GLN n 
1 344 ILE n 
1 345 LYS n 
1 346 THR n 
1 347 SER n 
1 348 SER n 
1 349 GLY n 
1 350 ALA n 
1 351 GLU n 
1 352 THR n 
1 353 SER n 
1 354 ALA n 
1 355 PHE n 
1 356 ILE n 
1 357 GLU n 
1 358 ARG n 
1 359 VAL n 
1 360 ALA n 
1 361 ASP n 
1 362 ILE n 
1 363 SER n 
1 364 GLN n 
1 365 HIS n 
1 366 MET n 
1 367 ALA n 
1 368 ALA n 
1 369 LEU n 
1 370 ALA n 
1 371 LEU n 
1 372 GLU n 
1 373 GLN n 
1 374 GLU n 
1 375 LYS n 
1 376 SER n 
1 377 ARG n 
1 378 GLN n 
1 379 HIS n 
1 380 ILE n 
1 381 GLU n 
1 382 GLN n 
1 383 LEU n 
1 384 ILE n 
1 385 GLN n 
1 386 PHE n 
1 387 ASP n 
1 388 PRO n 
1 389 MET n 
1 390 THR n 
1 391 GLY n 
1 392 LEU n 
1 393 PRO n 
1 394 ASN n 
1 395 ARG n 
1 396 ASN n 
1 397 ASN n 
1 398 LEU n 
1 399 HIS n 
1 400 ASN n 
1 401 TYR n 
1 402 LEU n 
1 403 ASP n 
1 404 ASP n 
1 405 LEU n 
1 406 VAL n 
1 407 ASP n 
1 408 LYS n 
1 409 ALA n 
1 410 VAL n 
1 411 SER n 
1 412 PRO n 
1 413 VAL n 
1 414 VAL n 
1 415 TYR n 
1 416 LEU n 
1 417 ILE n 
1 418 GLY n 
1 419 VAL n 
1 420 ASP n 
1 421 HIS n 
1 422 ILE n 
1 423 GLN n 
1 424 ASP n 
1 425 VAL n 
1 426 ILE n 
1 427 ASP n 
1 428 SER n 
1 429 LEU n 
1 430 GLY n 
1 431 TYR n 
1 432 ALA n 
1 433 TRP n 
1 434 ALA n 
1 435 ASP n 
1 436 GLN n 
1 437 ALA n 
1 438 LEU n 
1 439 LEU n 
1 440 GLU n 
1 441 VAL n 
1 442 VAL n 
1 443 ASN n 
1 444 ARG n 
1 445 PHE n 
1 446 ARG n 
1 447 GLU n 
1 448 LYS n 
1 449 LEU n 
1 450 LYS n 
1 451 PRO n 
1 452 ASP n 
1 453 GLN n 
1 454 TYR n 
1 455 LEU n 
1 456 CYS n 
1 457 ARG n 
1 458 ILE n 
1 459 GLU n 
1 460 GLY n 
1 461 THR n 
1 462 GLN n 
1 463 PHE n 
1 464 VAL n 
1 465 LEU n 
1 466 VAL n 
1 467 SER n 
1 468 LEU n 
1 469 GLU n 
1 470 ASN n 
1 471 ASP n 
1 472 VAL n 
1 473 SER n 
1 474 ASN n 
1 475 ILE n 
1 476 THR n 
1 477 GLN n 
1 478 ILE n 
1 479 ALA n 
1 480 ASP n 
1 481 GLU n 
1 482 LEU n 
1 483 ARG n 
1 484 ASN n 
1 485 VAL n 
1 486 VAL n 
1 487 SER n 
1 488 LYS n 
1 489 PRO n 
1 490 ILE n 
1 491 MET n 
1 492 ILE n 
1 493 ASP n 
1 494 ASP n 
1 495 LYS n 
1 496 PRO n 
1 497 PHE n 
1 498 PRO n 
1 499 LEU n 
1 500 THR n 
1 501 LEU n 
1 502 SER n 
1 503 ILE n 
1 504 GLY n 
1 505 ILE n 
1 506 SER n 
1 507 TYR n 
1 508 ASP n 
1 509 LEU n 
1 510 GLY n 
1 511 LYS n 
1 512 ASN n 
1 513 ARG n 
1 514 ASP n 
1 515 TYR n 
1 516 LEU n 
1 517 LEU n 
1 518 SER n 
1 519 THR n 
1 520 ALA n 
1 521 HIS n 
1 522 ASN n 
1 523 ALA n 
1 524 MET n 
1 525 ASP n 
1 526 TYR n 
1 527 ILE n 
1 528 ARG n 
1 529 LYS n 
1 530 ASN n 
1 531 GLY n 
1 532 GLY n 
1 533 ASN n 
1 534 GLY n 
1 535 TRP n 
1 536 GLN n 
1 537 PHE n 
1 538 PHE n 
1 539 SER n 
1 540 PRO n 
1 541 ALA n 
1 542 MET n 
1 543 ASN n 
1 544 GLU n 
1 545 MET n 
1 546 VAL n 
1 547 LYS n 
1 548 GLU n 
1 549 ARG n 
1 550 LEU n 
1 551 VAL n 
1 552 LEU n 
1 553 GLY n 
1 554 ALA n 
1 555 ALA n 
1 556 LEU n 
1 557 LYS n 
1 558 GLU n 
1 559 ALA n 
1 560 ILE n 
1 561 SER n 
1 562 ASN n 
1 563 ASN n 
1 564 GLN n 
1 565 LEU n 
1 566 LYS n 
1 567 LEU n 
1 568 VAL n 
1 569 TYR n 
1 570 GLN n 
1 571 PRO n 
1 572 GLN n 
1 573 ILE n 
1 574 PHE n 
1 575 ALA n 
1 576 GLU n 
1 577 THR n 
1 578 GLY n 
1 579 GLU n 
1 580 LEU n 
1 581 TYR n 
1 582 GLY n 
1 583 ILE n 
1 584 GLU n 
1 585 ALA n 
1 586 LEU n 
1 587 ALA n 
1 588 ARG n 
1 589 TRP n 
1 590 HIS n 
1 591 ASP n 
1 592 PRO n 
1 593 LEU n 
1 594 HIS n 
1 595 GLY n 
1 596 HIS n 
1 597 VAL n 
1 598 PRO n 
1 599 PRO n 
1 600 SER n 
1 601 ARG n 
1 602 PHE n 
1 603 ILE n 
1 604 PRO n 
1 605 LEU n 
1 606 ALA n 
1 607 GLU n 
1 608 GLU n 
1 609 ILE n 
1 610 GLY n 
1 611 GLU n 
1 612 ILE n 
1 613 GLU n 
1 614 ASN n 
1 615 ILE n 
1 616 GLY n 
1 617 ARG n 
1 618 TRP n 
1 619 VAL n 
1 620 ILE n 
1 621 ALA n 
1 622 GLU n 
1 623 ALA n 
1 624 CYS n 
1 625 ARG n 
1 626 GLN n 
1 627 LEU n 
1 628 ALA n 
1 629 GLU n 
1 630 TRP n 
1 631 ARG n 
1 632 SER n 
1 633 GLN n 
1 634 ASN n 
1 635 ILE n 
1 636 HIS n 
1 637 ILE n 
1 638 PRO n 
1 639 ALA n 
1 640 LEU n 
1 641 SER n 
1 642 VAL n 
1 643 ASN n 
1 644 LEU n 
1 645 SER n 
1 646 ALA n 
1 647 LEU n 
1 648 HIS n 
1 649 PHE n 
1 650 ARG n 
1 651 SER n 
1 652 ASN n 
1 653 GLN n 
1 654 LEU n 
1 655 PRO n 
1 656 ASN n 
1 657 GLN n 
1 658 VAL n 
1 659 SER n 
1 660 ASP n 
1 661 ALA n 
1 662 MET n 
1 663 HIS n 
1 664 ALA n 
1 665 TRP n 
1 666 GLY n 
1 667 ILE n 
1 668 ASP n 
1 669 GLY n 
1 670 HIS n 
1 671 GLN n 
1 672 LEU n 
1 673 THR n 
1 674 VAL n 
1 675 GLU n 
1 676 ILE n 
1 677 THR n 
1 678 GLU n 
1 679 SER n 
1 680 MET n 
1 681 MET n 
1 682 MET n 
1 683 GLU n 
1 684 HIS n 
1 685 ASP n 
1 686 THR n 
1 687 GLU n 
1 688 ILE n 
1 689 PHE n 
1 690 LYS n 
1 691 ARG n 
1 692 ILE n 
1 693 GLN n 
1 694 ILE n 
1 695 LEU n 
1 696 ARG n 
1 697 ASP n 
1 698 MET n 
1 699 GLY n 
1 700 VAL n 
1 701 GLY n 
1 702 LEU n 
1 703 SER n 
1 704 VAL n 
1 705 ASP n 
1 706 ASP n 
1 707 PHE n 
1 708 GLY n 
1 709 THR n 
1 710 GLY n 
1 711 PHE n 
1 712 SER n 
1 713 GLY n 
1 714 LEU n 
1 715 SER n 
1 716 ARG n 
1 717 LEU n 
1 718 VAL n 
1 719 SER n 
1 720 LEU n 
1 721 PRO n 
1 722 VAL n 
1 723 THR n 
1 724 GLU n 
1 725 ILE n 
1 726 LYS n 
1 727 ILE n 
1 728 ASP n 
1 729 LYS n 
1 730 SER n 
1 731 PHE n 
1 732 VAL n 
1 733 ASP n 
1 734 ARG n 
1 735 CYS n 
1 736 LEU n 
1 737 THR n 
1 738 GLU n 
1 739 LYS n 
1 740 ARG n 
1 741 ILE n 
1 742 LEU n 
1 743 ALA n 
1 744 LEU n 
1 745 LEU n 
1 746 GLU n 
1 747 ALA n 
1 748 ILE n 
1 749 THR n 
1 750 SER n 
1 751 ILE n 
1 752 GLY n 
1 753 GLN n 
1 754 SER n 
1 755 LEU n 
1 756 ASN n 
1 757 LEU n 
1 758 THR n 
1 759 VAL n 
1 760 VAL n 
1 761 ALA n 
1 762 GLU n 
1 763 GLY n 
1 764 VAL n 
1 765 GLU n 
1 766 THR n 
1 767 LYS n 
1 768 GLU n 
1 769 GLN n 
1 770 PHE n 
1 771 GLU n 
1 772 MET n 
1 773 LEU n 
1 774 ARG n 
1 775 LYS n 
1 776 ILE n 
1 777 HIS n 
1 778 CYS n 
1 779 ARG n 
1 780 VAL n 
1 781 ILE n 
1 782 GLN n 
1 783 GLY n 
1 784 TYR n 
1 785 PHE n 
1 786 PHE n 
1 787 SER n 
1 788 ARG n 
1 789 PRO n 
1 790 LEU n 
1 791 PRO n 
1 792 ALA n 
1 793 GLU n 
1 794 GLU n 
1 795 ILE n 
1 796 PRO n 
1 797 GLY n 
1 798 TRP n 
1 799 MET n 
1 800 SER n 
1 801 SER n 
1 802 VAL n 
1 803 LEU n 
1 804 PRO n 
1 805 LEU n 
1 806 LYS n 
1 807 ILE n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   807 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'dosP, dos, pdeO, yddU, b1489, JW1484' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     562 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                           ?    'C3 H7 N O2'       89.093  
ARG 'L-peptide linking' y ARGININE                          ?    'C6 H15 N4 O2 1'   175.209 
ASN 'L-peptide linking' y ASPARAGINE                        ?    'C4 H8 N2 O3'      132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                   ?    'C4 H7 N O4'       133.103 
CYS 'L-peptide linking' y CYSTEINE                          ?    'C3 H7 N O2 S'     121.158 
GLN 'L-peptide linking' y GLUTAMINE                         ?    'C5 H10 N2 O3'     146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                   ?    'C5 H9 N O4'       147.129 
GLY 'peptide linking'   y GLYCINE                           ?    'C2 H5 N O2'       75.067  
HEM non-polymer         . 'PROTOPORPHYRIN IX CONTAINING FE' HEME 'C34 H32 Fe N4 O4' 616.487 
HIS 'L-peptide linking' y HISTIDINE                         ?    'C6 H10 N3 O2 1'   156.162 
ILE 'L-peptide linking' y ISOLEUCINE                        ?    'C6 H13 N O2'      131.173 
LEU 'L-peptide linking' y LEUCINE                           ?    'C6 H13 N O2'      131.173 
LYS 'L-peptide linking' y LYSINE                            ?    'C6 H15 N2 O2 1'   147.195 
MET 'L-peptide linking' y METHIONINE                        ?    'C5 H11 N O2 S'    149.211 
PHE 'L-peptide linking' y PHENYLALANINE                     ?    'C9 H11 N O2'      165.189 
PRO 'L-peptide linking' y PROLINE                           ?    'C5 H9 N O2'       115.130 
SER 'L-peptide linking' y SERINE                            ?    'C3 H7 N O3'       105.093 
THR 'L-peptide linking' y THREONINE                         ?    'C4 H9 N O3'       119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                        ?    'C11 H12 N2 O2'    204.225 
TYR 'L-peptide linking' y TYROSINE                          ?    'C9 H11 N O3'      181.189 
VAL 'L-peptide linking' y VALINE                            ?    'C5 H11 N O2'      117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ARG 2   2   ?   ?   ?   A . n 
A 1 3   GLN 3   3   ?   ?   ?   A . n 
A 1 4   ASP 4   4   ?   ?   ?   A . n 
A 1 5   ALA 5   5   ?   ?   ?   A . n 
A 1 6   GLU 6   6   ?   ?   ?   A . n 
A 1 7   VAL 7   7   ?   ?   ?   A . n 
A 1 8   ILE 8   8   ?   ?   ?   A . n 
A 1 9   MET 9   9   ?   ?   ?   A . n 
A 1 10  LYS 10  10  ?   ?   ?   A . n 
A 1 11  LEU 11  11  ?   ?   ?   A . n 
A 1 12  THR 12  12  ?   ?   ?   A . n 
A 1 13  ASP 13  13  ?   ?   ?   A . n 
A 1 14  ALA 14  14  ?   ?   ?   A . n 
A 1 15  ASP 15  15  ?   ?   ?   A . n 
A 1 16  SER 16  16  ?   ?   ?   A . n 
A 1 17  ALA 17  17  ?   ?   ?   A . n 
A 1 18  ALA 18  18  ?   ?   ?   A . n 
A 1 19  ASP 19  19  ?   ?   ?   A . n 
A 1 20  GLY 20  20  20  GLY GLY A . n 
A 1 21  ILE 21  21  21  ILE ILE A . n 
A 1 22  PHE 22  22  22  PHE PHE A . n 
A 1 23  PHE 23  23  23  PHE PHE A . n 
A 1 24  PRO 24  24  24  PRO PRO A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  LEU 26  26  26  LEU LEU A . n 
A 1 27  GLU 27  27  27  GLU GLU A . n 
A 1 28  GLN 28  28  28  GLN GLN A . n 
A 1 29  ASN 29  29  29  ASN ASN A . n 
A 1 30  MET 30  30  30  MET MET A . n 
A 1 31  MET 31  31  31  MET MET A . n 
A 1 32  GLY 32  32  32  GLY GLY A . n 
A 1 33  ALA 33  33  33  ALA ALA A . n 
A 1 34  VAL 34  34  34  VAL VAL A . n 
A 1 35  LEU 35  35  35  LEU LEU A . n 
A 1 36  ILE 36  36  36  ILE ILE A . n 
A 1 37  ASN 37  37  37  ASN ASN A . n 
A 1 38  GLU 38  38  38  GLU GLU A . n 
A 1 39  ASN 39  39  39  ASN ASN A . n 
A 1 40  ASP 40  40  40  ASP ASP A . n 
A 1 41  GLU 41  41  41  GLU GLU A . n 
A 1 42  VAL 42  42  42  VAL VAL A . n 
A 1 43  MET 43  43  43  MET MET A . n 
A 1 44  PHE 44  44  44  PHE PHE A . n 
A 1 45  PHE 45  45  45  PHE PHE A . n 
A 1 46  ASN 46  46  46  ASN ASN A . n 
A 1 47  PRO 47  47  47  PRO PRO A . n 
A 1 48  ALA 48  48  48  ALA ALA A . n 
A 1 49  ALA 49  49  49  ALA ALA A . n 
A 1 50  GLU 50  50  50  GLU GLU A . n 
A 1 51  LYS 51  51  51  LYS LYS A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  TRP 53  53  53  TRP TRP A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  LYS 56  56  56  LYS LYS A . n 
A 1 57  ARG 57  57  57  ARG ARG A . n 
A 1 58  GLU 58  58  58  GLU GLU A . n 
A 1 59  GLU 59  59  59  GLU GLU A . n 
A 1 60  VAL 60  60  60  VAL VAL A . n 
A 1 61  ILE 61  61  61  ILE ILE A . n 
A 1 62  GLY 62  62  62  GLY GLY A . n 
A 1 63  ASN 63  63  63  ASN ASN A . n 
A 1 64  ASN 64  64  64  ASN ASN A . n 
A 1 65  ILE 65  65  65  ILE ILE A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  MET 67  67  67  MET MET A . n 
A 1 68  LEU 68  68  68  LEU LEU A . n 
A 1 69  ILE 69  69  69  ILE ILE A . n 
A 1 70  PRO 70  70  70  PRO PRO A . n 
A 1 71  ARG 71  71  71  ARG ARG A . n 
A 1 72  ASP 72  72  72  ASP ASP A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ARG 74  74  74  ARG ARG A . n 
A 1 75  PRO 75  75  75  PRO PRO A . n 
A 1 76  ALA 76  76  76  ALA ALA A . n 
A 1 77  HIS 77  77  77  HIS HIS A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLU 79  79  79  GLU GLU A . n 
A 1 80  TYR 80  80  80  TYR TYR A . n 
A 1 81  ILE 81  81  81  ILE ILE A . n 
A 1 82  ARG 82  82  82  ARG ARG A . n 
A 1 83  HIS 83  83  83  HIS HIS A . n 
A 1 84  ASN 84  84  84  ASN ASN A . n 
A 1 85  ARG 85  85  85  ARG ARG A . n 
A 1 86  GLU 86  86  86  GLU GLU A . n 
A 1 87  GLY 87  87  87  GLY GLY A . n 
A 1 88  GLY 88  88  88  GLY GLY A . n 
A 1 89  LYS 89  89  89  LYS LYS A . n 
A 1 90  ALA 90  90  90  ALA ALA A . n 
A 1 91  ARG 91  91  91  ARG ARG A . n 
A 1 92  VAL 92  92  92  VAL VAL A . n 
A 1 93  GLU 93  93  93  GLU GLU A . n 
A 1 94  GLY 94  94  94  GLY GLY A . n 
A 1 95  MET 95  95  95  MET MET A . n 
A 1 96  SER 96  96  96  SER SER A . n 
A 1 97  ALA 97  97  97  ALA ALA A . n 
A 1 98  GLU 98  98  98  GLU GLU A . n 
A 1 99  LEU 99  99  99  LEU LEU A . n 
A 1 100 GLN 100 100 100 GLN GLN A . n 
A 1 101 LEU 101 101 101 LEU LEU A . n 
A 1 102 GLU 102 102 102 GLU GLU A . n 
A 1 103 LYS 103 103 103 LYS LYS A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 ASP 105 105 105 ASP ASP A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 LYS 108 108 108 LYS LYS A . n 
A 1 109 ILE 109 109 109 ILE ILE A . n 
A 1 110 TRP 110 110 110 TRP TRP A . n 
A 1 111 THR 111 111 111 THR THR A . n 
A 1 112 ARG 112 112 112 ARG ARG A . n 
A 1 113 PHE 113 113 113 PHE PHE A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 SER 116 116 116 SER SER A . n 
A 1 117 LYS 117 117 117 LYS LYS A . n 
A 1 118 VAL 118 118 118 VAL VAL A . n 
A 1 119 SER 119 119 119 SER SER A . n 
A 1 120 ALA 120 120 120 ALA ALA A . n 
A 1 121 GLU 121 121 121 GLU GLU A . n 
A 1 122 GLY 122 122 122 GLY GLY A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 VAL 124 124 124 VAL VAL A . n 
A 1 125 TYR 125 125 125 TYR TYR A . n 
A 1 126 TYR 126 126 126 TYR TYR A . n 
A 1 127 LEU 127 127 127 LEU LEU A . n 
A 1 128 ALA 128 128 128 ALA ALA A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 VAL 130 130 130 VAL VAL A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 ASP 132 132 132 ASP ASP A . n 
A 1 133 ALA 133 133 133 ALA ALA A . n 
A 1 134 SER 134 134 134 SER SER A . n 
A 1 135 VAL 135 135 135 VAL VAL A . n 
A 1 136 GLU 136 136 136 GLU GLU A . n 
A 1 137 MET 137 137 137 MET MET A . n 
A 1 138 ALA 138 138 138 ALA ALA A . n 
A 1 139 GLN 139 139 139 GLN GLN A . n 
A 1 140 LYS 140 140 140 LYS LYS A . n 
A 1 141 GLU 141 141 141 GLU GLU A . n 
A 1 142 GLN 142 142 142 GLN GLN A . n 
A 1 143 THR 143 143 143 THR THR A . n 
A 1 144 ARG 144 144 144 ARG ARG A . n 
A 1 145 GLN 145 145 145 GLN GLN A . n 
A 1 146 LEU 146 146 146 LEU LEU A . n 
A 1 147 ILE 147 147 147 ILE ILE A . n 
A 1 148 ILE 148 148 148 ILE ILE A . n 
A 1 149 ALA 149 149 149 ALA ALA A . n 
A 1 150 VAL 150 150 150 VAL VAL A . n 
A 1 151 ASP 151 151 151 ASP ASP A . n 
A 1 152 HIS 152 152 152 HIS HIS A . n 
A 1 153 LEU 153 153 153 LEU LEU A . n 
A 1 154 ASP 154 154 154 ASP ASP A . n 
A 1 155 ARG 155 155 155 ARG ARG A . n 
A 1 156 PRO 156 156 156 PRO PRO A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 ILE 158 158 158 ILE ILE A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ASP 161 161 161 ASP ASP A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 GLU 163 163 163 GLU GLU A . n 
A 1 164 ARG 164 164 164 ARG ARG A . n 
A 1 165 HIS 165 165 165 HIS HIS A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 GLN 168 168 168 GLN GLN A . n 
A 1 169 CYS 169 169 169 CYS CYS A . n 
A 1 170 ASN 170 170 170 ASN ASN A . n 
A 1 171 ARG 171 171 171 ARG ARG A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 PHE 173 173 173 PHE PHE A . n 
A 1 174 THR 174 174 174 THR THR A . n 
A 1 175 GLU 175 175 175 GLU GLU A . n 
A 1 176 MET 176 176 176 MET MET A . n 
A 1 177 PHE 177 177 177 PHE PHE A . n 
A 1 178 GLY 178 178 178 GLY GLY A . n 
A 1 179 TYR 179 179 179 TYR TYR A . n 
A 1 180 CYS 180 180 180 CYS CYS A . n 
A 1 181 ILE 181 181 181 ILE ILE A . n 
A 1 182 SER 182 182 182 SER SER A . n 
A 1 183 GLU 183 183 183 GLU GLU A . n 
A 1 184 ALA 184 184 184 ALA ALA A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 GLY 186 186 186 GLY GLY A . n 
A 1 187 MET 187 187 187 MET MET A . n 
A 1 188 GLN 188 188 188 GLN GLN A . n 
A 1 189 PRO 189 189 189 PRO PRO A . n 
A 1 190 ASP 190 190 190 ASP ASP A . n 
A 1 191 THR 191 191 191 THR THR A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 LEU 193 193 193 LEU LEU A . n 
A 1 194 ASN 194 194 194 ASN ASN A . n 
A 1 195 THR 195 195 195 THR THR A . n 
A 1 196 PRO 196 196 196 PRO PRO A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 PRO 199 199 199 PRO PRO A . n 
A 1 200 ALA 200 200 200 ALA ALA A . n 
A 1 201 ASP 201 201 201 ASP ASP A . n 
A 1 202 ASN 202 202 202 ASN ASN A . n 
A 1 203 ARG 203 203 203 ARG ARG A . n 
A 1 204 ILE 204 204 204 ILE ILE A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 LEU 206 206 206 LEU LEU A . n 
A 1 207 GLN 207 207 207 GLN GLN A . n 
A 1 208 GLN 208 208 208 GLN GLN A . n 
A 1 209 LEU 209 209 209 LEU LEU A . n 
A 1 210 LEU 210 210 210 LEU LEU A . n 
A 1 211 TRP 211 211 211 TRP TRP A . n 
A 1 212 LYS 212 212 212 LYS LYS A . n 
A 1 213 THR 213 213 213 THR THR A . n 
A 1 214 ALA 214 214 214 ALA ALA A . n 
A 1 215 ARG 215 215 215 ARG ARG A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 GLN 217 217 217 GLN GLN A . n 
A 1 218 ASP 218 218 218 ASP ASP A . n 
A 1 219 GLU 219 219 219 GLU GLU A . n 
A 1 220 PHE 220 220 220 PHE PHE A . n 
A 1 221 LEU 221 221 221 LEU LEU A . n 
A 1 222 LEU 222 222 222 LEU LEU A . n 
A 1 223 LEU 223 223 223 LEU LEU A . n 
A 1 224 THR 224 224 224 THR THR A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 THR 226 226 226 THR THR A . n 
A 1 227 GLY 227 227 227 GLY GLY A . n 
A 1 228 GLU 228 228 228 GLU GLU A . n 
A 1 229 LYS 229 229 229 LYS LYS A . n 
A 1 230 ILE 230 230 230 ILE ILE A . n 
A 1 231 TRP 231 231 231 TRP TRP A . n 
A 1 232 ILE 232 232 232 ILE ILE A . n 
A 1 233 LYS 233 233 233 LYS LYS A . n 
A 1 234 ALA 234 234 234 ALA ALA A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 ILE 236 236 236 ILE ILE A . n 
A 1 237 SER 237 237 237 SER SER A . n 
A 1 238 PRO 238 238 238 PRO PRO A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 ASP 241 241 241 ASP ASP A . n 
A 1 242 VAL 242 242 242 VAL VAL A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 ALA 244 244 244 ALA ALA A . n 
A 1 245 HIS 245 245 245 HIS HIS A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 GLN 247 247 247 GLN GLN A . n 
A 1 248 ASN 248 248 248 ASN ASN A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 VAL 250 250 250 VAL VAL A . n 
A 1 251 MET 251 251 251 MET MET A . n 
A 1 252 THR 252 252 252 THR THR A . n 
A 1 253 PHE 253 253 253 PHE PHE A . n 
A 1 254 SER 254 254 254 SER SER A . n 
A 1 255 ASP 255 255 255 ASP ASP A . n 
A 1 256 ILE 256 256 256 ILE ILE A . n 
A 1 257 THR 257 257 257 THR THR A . n 
A 1 258 GLU 258 258 258 GLU GLU A . n 
A 1 259 GLU 259 259 259 GLU GLU A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 ILE 262 262 262 ILE ILE A . n 
A 1 263 ARG 263 263 263 ARG ARG A . n 
A 1 264 GLN 264 264 264 GLN GLN A . n 
A 1 265 LEU 265 265 265 LEU LEU A . n 
A 1 266 GLU 266 266 266 GLU GLU A . n 
A 1 267 GLY 267 267 267 GLY GLY A . n 
A 1 268 ASN 268 268 268 ASN ASN A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 LEU 270 270 270 LEU LEU A . n 
A 1 271 ALA 271 271 271 ALA ALA A . n 
A 1 272 ALA 272 272 272 ALA ALA A . n 
A 1 273 MET 273 273 273 MET MET A . n 
A 1 274 CYS 274 274 274 CYS CYS A . n 
A 1 275 SER 275 275 275 SER SER A . n 
A 1 276 SER 276 276 276 SER SER A . n 
A 1 277 PRO 277 277 277 PRO PRO A . n 
A 1 278 PRO 278 278 278 PRO PRO A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 HIS 280 280 280 HIS HIS A . n 
A 1 281 GLU 281 281 281 GLU GLU A . n 
A 1 282 MET 282 282 282 MET MET A . n 
A 1 283 GLY 283 283 283 GLY GLY A . n 
A 1 284 GLU 284 284 284 GLU GLU A . n 
A 1 285 ILE 285 285 285 ILE ILE A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 CYS 287 287 287 CYS CYS A . n 
A 1 288 ARG 288 288 288 ARG ARG A . n 
A 1 289 ASN 289 289 289 ASN ASN A . n 
A 1 290 ILE 290 290 290 ILE ILE A . n 
A 1 291 GLU 291 291 291 GLU GLU A . n 
A 1 292 SER 292 292 292 SER SER A . n 
A 1 293 VAL 293 293 293 VAL VAL A . n 
A 1 294 LEU 294 294 294 LEU LEU A . n 
A 1 295 ASN 295 295 295 ASN ASN A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 SER 297 297 297 SER SER A . n 
A 1 298 HIS 298 298 298 HIS HIS A . n 
A 1 299 VAL 299 299 299 VAL VAL A . n 
A 1 300 SER 300 300 300 SER SER A . n 
A 1 301 LEU 301 301 301 LEU LEU A . n 
A 1 302 PHE 302 302 302 PHE PHE A . n 
A 1 303 ALA 303 303 303 ALA ALA A . n 
A 1 304 LEU 304 304 304 LEU LEU A . n 
A 1 305 ARG 305 305 305 ARG ARG A . n 
A 1 306 ASN 306 306 306 ASN ASN A . n 
A 1 307 GLY 307 307 307 GLY GLY A . n 
A 1 308 MET 308 308 308 MET MET A . n 
A 1 309 PRO 309 309 309 PRO PRO A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 HIS 311 311 311 HIS HIS A . n 
A 1 312 TRP 312 312 312 TRP TRP A . n 
A 1 313 ALA 313 313 313 ALA ALA A . n 
A 1 314 SER 314 314 314 SER SER A . n 
A 1 315 SER 315 315 315 SER SER A . n 
A 1 316 SER 316 316 316 SER SER A . n 
A 1 317 HIS 317 317 317 HIS HIS A . n 
A 1 318 GLY 318 318 318 GLY GLY A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 GLU 320 320 320 GLU GLU A . n 
A 1 321 ILE 321 321 321 ILE ILE A . n 
A 1 322 GLN 322 322 322 GLN GLN A . n 
A 1 323 ASN 323 323 323 ASN ASN A . n 
A 1 324 ALA 324 324 324 ALA ALA A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 SER 326 326 326 SER SER A . n 
A 1 327 TRP 327 327 327 TRP TRP A . n 
A 1 328 SER 328 328 328 SER SER A . n 
A 1 329 ALA 329 329 329 ALA ALA A . n 
A 1 330 THR 330 330 330 THR THR A . n 
A 1 331 ILE 331 331 331 ILE ILE A . n 
A 1 332 ARG 332 332 332 ARG ARG A . n 
A 1 333 GLN 333 333 333 GLN GLN A . n 
A 1 334 ARG 334 334 334 ARG ARG A . n 
A 1 335 ASP 335 335 335 ASP ASP A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 ALA 337 337 337 ALA ALA A . n 
A 1 338 PRO 338 338 338 PRO PRO A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 GLY 340 340 340 GLY GLY A . n 
A 1 341 ILE 341 341 341 ILE ILE A . n 
A 1 342 LEU 342 342 342 LEU LEU A . n 
A 1 343 GLN 343 343 343 GLN GLN A . n 
A 1 344 ILE 344 344 344 ILE ILE A . n 
A 1 345 LYS 345 345 345 LYS LYS A . n 
A 1 346 THR 346 346 346 THR THR A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 SER 348 348 348 SER SER A . n 
A 1 349 GLY 349 349 349 GLY GLY A . n 
A 1 350 ALA 350 350 350 ALA ALA A . n 
A 1 351 GLU 351 351 351 GLU GLU A . n 
A 1 352 THR 352 352 352 THR THR A . n 
A 1 353 SER 353 353 353 SER SER A . n 
A 1 354 ALA 354 354 354 ALA ALA A . n 
A 1 355 PHE 355 355 355 PHE PHE A . n 
A 1 356 ILE 356 356 356 ILE ILE A . n 
A 1 357 GLU 357 357 357 GLU GLU A . n 
A 1 358 ARG 358 358 358 ARG ARG A . n 
A 1 359 VAL 359 359 359 VAL VAL A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ASP 361 361 361 ASP ASP A . n 
A 1 362 ILE 362 362 362 ILE ILE A . n 
A 1 363 SER 363 363 363 SER SER A . n 
A 1 364 GLN 364 364 364 GLN GLN A . n 
A 1 365 HIS 365 365 365 HIS HIS A . n 
A 1 366 MET 366 366 366 MET MET A . n 
A 1 367 ALA 367 367 367 ALA ALA A . n 
A 1 368 ALA 368 368 368 ALA ALA A . n 
A 1 369 LEU 369 369 369 LEU LEU A . n 
A 1 370 ALA 370 370 370 ALA ALA A . n 
A 1 371 LEU 371 371 371 LEU LEU A . n 
A 1 372 GLU 372 372 372 GLU GLU A . n 
A 1 373 GLN 373 373 373 GLN GLN A . n 
A 1 374 GLU 374 374 374 GLU GLU A . n 
A 1 375 LYS 375 375 375 LYS LYS A . n 
A 1 376 SER 376 376 376 SER SER A . n 
A 1 377 ARG 377 377 377 ARG ARG A . n 
A 1 378 GLN 378 378 378 GLN GLN A . n 
A 1 379 HIS 379 379 379 HIS HIS A . n 
A 1 380 ILE 380 380 380 ILE ILE A . n 
A 1 381 GLU 381 381 381 GLU GLU A . n 
A 1 382 GLN 382 382 382 GLN GLN A . n 
A 1 383 LEU 383 383 383 LEU LEU A . n 
A 1 384 ILE 384 384 384 ILE ILE A . n 
A 1 385 GLN 385 385 385 GLN GLN A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 ASP 387 387 387 ASP ASP A . n 
A 1 388 PRO 388 388 388 PRO PRO A . n 
A 1 389 MET 389 389 389 MET MET A . n 
A 1 390 THR 390 390 390 THR THR A . n 
A 1 391 GLY 391 391 391 GLY GLY A . n 
A 1 392 LEU 392 392 392 LEU LEU A . n 
A 1 393 PRO 393 393 393 PRO PRO A . n 
A 1 394 ASN 394 394 394 ASN ASN A . n 
A 1 395 ARG 395 395 395 ARG ARG A . n 
A 1 396 ASN 396 396 396 ASN ASN A . n 
A 1 397 ASN 397 397 397 ASN ASN A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 HIS 399 399 399 HIS HIS A . n 
A 1 400 ASN 400 400 400 ASN ASN A . n 
A 1 401 TYR 401 401 401 TYR TYR A . n 
A 1 402 LEU 402 402 402 LEU LEU A . n 
A 1 403 ASP 403 403 403 ASP ASP A . n 
A 1 404 ASP 404 404 404 ASP ASP A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 VAL 406 406 406 VAL VAL A . n 
A 1 407 ASP 407 407 407 ASP ASP A . n 
A 1 408 LYS 408 408 408 LYS LYS A . n 
A 1 409 ALA 409 409 409 ALA ALA A . n 
A 1 410 VAL 410 410 410 VAL VAL A . n 
A 1 411 SER 411 411 411 SER SER A . n 
A 1 412 PRO 412 412 412 PRO PRO A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 VAL 414 414 414 VAL VAL A . n 
A 1 415 TYR 415 415 415 TYR TYR A . n 
A 1 416 LEU 416 416 416 LEU LEU A . n 
A 1 417 ILE 417 417 417 ILE ILE A . n 
A 1 418 GLY 418 418 418 GLY GLY A . n 
A 1 419 VAL 419 419 419 VAL VAL A . n 
A 1 420 ASP 420 420 420 ASP ASP A . n 
A 1 421 HIS 421 421 421 HIS HIS A . n 
A 1 422 ILE 422 422 422 ILE ILE A . n 
A 1 423 GLN 423 423 423 GLN GLN A . n 
A 1 424 ASP 424 424 424 ASP ASP A . n 
A 1 425 VAL 425 425 425 VAL VAL A . n 
A 1 426 ILE 426 426 426 ILE ILE A . n 
A 1 427 ASP 427 427 427 ASP ASP A . n 
A 1 428 SER 428 428 428 SER SER A . n 
A 1 429 LEU 429 429 429 LEU LEU A . n 
A 1 430 GLY 430 430 430 GLY GLY A . n 
A 1 431 TYR 431 431 431 TYR TYR A . n 
A 1 432 ALA 432 432 432 ALA ALA A . n 
A 1 433 TRP 433 433 433 TRP TRP A . n 
A 1 434 ALA 434 434 434 ALA ALA A . n 
A 1 435 ASP 435 435 435 ASP ASP A . n 
A 1 436 GLN 436 436 436 GLN GLN A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 LEU 438 438 438 LEU LEU A . n 
A 1 439 LEU 439 439 439 LEU LEU A . n 
A 1 440 GLU 440 440 440 GLU GLU A . n 
A 1 441 VAL 441 441 441 VAL VAL A . n 
A 1 442 VAL 442 442 442 VAL VAL A . n 
A 1 443 ASN 443 443 443 ASN ASN A . n 
A 1 444 ARG 444 444 444 ARG ARG A . n 
A 1 445 PHE 445 445 445 PHE PHE A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 GLU 447 447 447 GLU GLU A . n 
A 1 448 LYS 448 448 448 LYS LYS A . n 
A 1 449 LEU 449 449 449 LEU LEU A . n 
A 1 450 LYS 450 450 450 LYS LYS A . n 
A 1 451 PRO 451 451 451 PRO PRO A . n 
A 1 452 ASP 452 452 452 ASP ASP A . n 
A 1 453 GLN 453 453 453 GLN GLN A . n 
A 1 454 TYR 454 454 454 TYR TYR A . n 
A 1 455 LEU 455 455 455 LEU LEU A . n 
A 1 456 CYS 456 456 456 CYS CYS A . n 
A 1 457 ARG 457 457 457 ARG ARG A . n 
A 1 458 ILE 458 458 458 ILE ILE A . n 
A 1 459 GLU 459 459 459 GLU GLU A . n 
A 1 460 GLY 460 460 460 GLY GLY A . n 
A 1 461 THR 461 461 461 THR THR A . n 
A 1 462 GLN 462 462 462 GLN GLN A . n 
A 1 463 PHE 463 463 463 PHE PHE A . n 
A 1 464 VAL 464 464 464 VAL VAL A . n 
A 1 465 LEU 465 465 465 LEU LEU A . n 
A 1 466 VAL 466 466 466 VAL VAL A . n 
A 1 467 SER 467 467 467 SER SER A . n 
A 1 468 LEU 468 468 468 LEU LEU A . n 
A 1 469 GLU 469 469 469 GLU GLU A . n 
A 1 470 ASN 470 470 470 ASN ASN A . n 
A 1 471 ASP 471 471 471 ASP ASP A . n 
A 1 472 VAL 472 472 472 VAL VAL A . n 
A 1 473 SER 473 473 473 SER SER A . n 
A 1 474 ASN 474 474 474 ASN ASN A . n 
A 1 475 ILE 475 475 475 ILE ILE A . n 
A 1 476 THR 476 476 476 THR THR A . n 
A 1 477 GLN 477 477 477 GLN GLN A . n 
A 1 478 ILE 478 478 478 ILE ILE A . n 
A 1 479 ALA 479 479 479 ALA ALA A . n 
A 1 480 ASP 480 480 480 ASP ASP A . n 
A 1 481 GLU 481 481 481 GLU GLU A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 ARG 483 483 483 ARG ARG A . n 
A 1 484 ASN 484 484 484 ASN ASN A . n 
A 1 485 VAL 485 485 485 VAL VAL A . n 
A 1 486 VAL 486 486 486 VAL VAL A . n 
A 1 487 SER 487 487 487 SER SER A . n 
A 1 488 LYS 488 488 488 LYS LYS A . n 
A 1 489 PRO 489 489 489 PRO PRO A . n 
A 1 490 ILE 490 490 490 ILE ILE A . n 
A 1 491 MET 491 491 491 MET MET A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 ASP 493 493 493 ASP ASP A . n 
A 1 494 ASP 494 494 494 ASP ASP A . n 
A 1 495 LYS 495 495 495 LYS LYS A . n 
A 1 496 PRO 496 496 496 PRO PRO A . n 
A 1 497 PHE 497 497 497 PHE PHE A . n 
A 1 498 PRO 498 498 498 PRO PRO A . n 
A 1 499 LEU 499 499 499 LEU LEU A . n 
A 1 500 THR 500 500 500 THR THR A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 SER 502 502 502 SER SER A . n 
A 1 503 ILE 503 503 503 ILE ILE A . n 
A 1 504 GLY 504 504 504 GLY GLY A . n 
A 1 505 ILE 505 505 505 ILE ILE A . n 
A 1 506 SER 506 506 506 SER SER A . n 
A 1 507 TYR 507 507 507 TYR TYR A . n 
A 1 508 ASP 508 508 508 ASP ASP A . n 
A 1 509 LEU 509 509 509 LEU LEU A . n 
A 1 510 GLY 510 510 510 GLY GLY A . n 
A 1 511 LYS 511 511 511 LYS LYS A . n 
A 1 512 ASN 512 512 512 ASN ASN A . n 
A 1 513 ARG 513 513 513 ARG ARG A . n 
A 1 514 ASP 514 514 514 ASP ASP A . n 
A 1 515 TYR 515 515 515 TYR TYR A . n 
A 1 516 LEU 516 516 516 LEU LEU A . n 
A 1 517 LEU 517 517 517 LEU LEU A . n 
A 1 518 SER 518 518 518 SER SER A . n 
A 1 519 THR 519 519 519 THR THR A . n 
A 1 520 ALA 520 520 520 ALA ALA A . n 
A 1 521 HIS 521 521 521 HIS HIS A . n 
A 1 522 ASN 522 522 522 ASN ASN A . n 
A 1 523 ALA 523 523 523 ALA ALA A . n 
A 1 524 MET 524 524 524 MET MET A . n 
A 1 525 ASP 525 525 525 ASP ASP A . n 
A 1 526 TYR 526 526 526 TYR TYR A . n 
A 1 527 ILE 527 527 527 ILE ILE A . n 
A 1 528 ARG 528 528 528 ARG ARG A . n 
A 1 529 LYS 529 529 529 LYS LYS A . n 
A 1 530 ASN 530 530 530 ASN ASN A . n 
A 1 531 GLY 531 531 531 GLY GLY A . n 
A 1 532 GLY 532 532 532 GLY GLY A . n 
A 1 533 ASN 533 533 533 ASN ASN A . n 
A 1 534 GLY 534 534 534 GLY GLY A . n 
A 1 535 TRP 535 535 535 TRP TRP A . n 
A 1 536 GLN 536 536 536 GLN GLN A . n 
A 1 537 PHE 537 537 537 PHE PHE A . n 
A 1 538 PHE 538 538 538 PHE PHE A . n 
A 1 539 SER 539 539 539 SER SER A . n 
A 1 540 PRO 540 540 540 PRO PRO A . n 
A 1 541 ALA 541 541 541 ALA ALA A . n 
A 1 542 MET 542 542 542 MET MET A . n 
A 1 543 ASN 543 543 543 ASN ASN A . n 
A 1 544 GLU 544 544 544 GLU GLU A . n 
A 1 545 MET 545 545 545 MET MET A . n 
A 1 546 VAL 546 546 546 VAL VAL A . n 
A 1 547 LYS 547 547 547 LYS LYS A . n 
A 1 548 GLU 548 548 548 GLU GLU A . n 
A 1 549 ARG 549 549 549 ARG ARG A . n 
A 1 550 LEU 550 550 550 LEU LEU A . n 
A 1 551 VAL 551 551 551 VAL VAL A . n 
A 1 552 LEU 552 552 552 LEU LEU A . n 
A 1 553 GLY 553 553 553 GLY GLY A . n 
A 1 554 ALA 554 554 554 ALA ALA A . n 
A 1 555 ALA 555 555 555 ALA ALA A . n 
A 1 556 LEU 556 556 556 LEU LEU A . n 
A 1 557 LYS 557 557 557 LYS LYS A . n 
A 1 558 GLU 558 558 558 GLU GLU A . n 
A 1 559 ALA 559 559 559 ALA ALA A . n 
A 1 560 ILE 560 560 560 ILE ILE A . n 
A 1 561 SER 561 561 561 SER SER A . n 
A 1 562 ASN 562 562 562 ASN ASN A . n 
A 1 563 ASN 563 563 563 ASN ASN A . n 
A 1 564 GLN 564 564 564 GLN GLN A . n 
A 1 565 LEU 565 565 565 LEU LEU A . n 
A 1 566 LYS 566 566 566 LYS LYS A . n 
A 1 567 LEU 567 567 567 LEU LEU A . n 
A 1 568 VAL 568 568 568 VAL VAL A . n 
A 1 569 TYR 569 569 569 TYR TYR A . n 
A 1 570 GLN 570 570 570 GLN GLN A . n 
A 1 571 PRO 571 571 571 PRO PRO A . n 
A 1 572 GLN 572 572 572 GLN GLN A . n 
A 1 573 ILE 573 573 573 ILE ILE A . n 
A 1 574 PHE 574 574 574 PHE PHE A . n 
A 1 575 ALA 575 575 575 ALA ALA A . n 
A 1 576 GLU 576 576 576 GLU GLU A . n 
A 1 577 THR 577 577 577 THR THR A . n 
A 1 578 GLY 578 578 578 GLY GLY A . n 
A 1 579 GLU 579 579 579 GLU GLU A . n 
A 1 580 LEU 580 580 580 LEU LEU A . n 
A 1 581 TYR 581 581 581 TYR TYR A . n 
A 1 582 GLY 582 582 582 GLY GLY A . n 
A 1 583 ILE 583 583 583 ILE ILE A . n 
A 1 584 GLU 584 584 584 GLU GLU A . n 
A 1 585 ALA 585 585 585 ALA ALA A . n 
A 1 586 LEU 586 586 586 LEU LEU A . n 
A 1 587 ALA 587 587 587 ALA ALA A . n 
A 1 588 ARG 588 588 588 ARG ARG A . n 
A 1 589 TRP 589 589 589 TRP TRP A . n 
A 1 590 HIS 590 590 590 HIS HIS A . n 
A 1 591 ASP 591 591 591 ASP ASP A . n 
A 1 592 PRO 592 592 592 PRO PRO A . n 
A 1 593 LEU 593 593 593 LEU LEU A . n 
A 1 594 HIS 594 594 594 HIS HIS A . n 
A 1 595 GLY 595 595 595 GLY GLY A . n 
A 1 596 HIS 596 596 596 HIS HIS A . n 
A 1 597 VAL 597 597 597 VAL VAL A . n 
A 1 598 PRO 598 598 598 PRO PRO A . n 
A 1 599 PRO 599 599 599 PRO PRO A . n 
A 1 600 SER 600 600 600 SER SER A . n 
A 1 601 ARG 601 601 601 ARG ARG A . n 
A 1 602 PHE 602 602 602 PHE PHE A . n 
A 1 603 ILE 603 603 603 ILE ILE A . n 
A 1 604 PRO 604 604 604 PRO PRO A . n 
A 1 605 LEU 605 605 605 LEU LEU A . n 
A 1 606 ALA 606 606 606 ALA ALA A . n 
A 1 607 GLU 607 607 607 GLU GLU A . n 
A 1 608 GLU 608 608 608 GLU GLU A . n 
A 1 609 ILE 609 609 609 ILE ILE A . n 
A 1 610 GLY 610 610 610 GLY GLY A . n 
A 1 611 GLU 611 611 611 GLU GLU A . n 
A 1 612 ILE 612 612 612 ILE ILE A . n 
A 1 613 GLU 613 613 613 GLU GLU A . n 
A 1 614 ASN 614 614 614 ASN ASN A . n 
A 1 615 ILE 615 615 615 ILE ILE A . n 
A 1 616 GLY 616 616 616 GLY GLY A . n 
A 1 617 ARG 617 617 617 ARG ARG A . n 
A 1 618 TRP 618 618 618 TRP TRP A . n 
A 1 619 VAL 619 619 619 VAL VAL A . n 
A 1 620 ILE 620 620 620 ILE ILE A . n 
A 1 621 ALA 621 621 621 ALA ALA A . n 
A 1 622 GLU 622 622 622 GLU GLU A . n 
A 1 623 ALA 623 623 623 ALA ALA A . n 
A 1 624 CYS 624 624 624 CYS CYS A . n 
A 1 625 ARG 625 625 625 ARG ARG A . n 
A 1 626 GLN 626 626 626 GLN GLN A . n 
A 1 627 LEU 627 627 627 LEU LEU A . n 
A 1 628 ALA 628 628 628 ALA ALA A . n 
A 1 629 GLU 629 629 629 GLU GLU A . n 
A 1 630 TRP 630 630 630 TRP TRP A . n 
A 1 631 ARG 631 631 631 ARG ARG A . n 
A 1 632 SER 632 632 632 SER SER A . n 
A 1 633 GLN 633 633 633 GLN GLN A . n 
A 1 634 ASN 634 634 634 ASN ASN A . n 
A 1 635 ILE 635 635 635 ILE ILE A . n 
A 1 636 HIS 636 636 636 HIS HIS A . n 
A 1 637 ILE 637 637 637 ILE ILE A . n 
A 1 638 PRO 638 638 638 PRO PRO A . n 
A 1 639 ALA 639 639 639 ALA ALA A . n 
A 1 640 LEU 640 640 640 LEU LEU A . n 
A 1 641 SER 641 641 641 SER SER A . n 
A 1 642 VAL 642 642 642 VAL VAL A . n 
A 1 643 ASN 643 643 643 ASN ASN A . n 
A 1 644 LEU 644 644 644 LEU LEU A . n 
A 1 645 SER 645 645 645 SER SER A . n 
A 1 646 ALA 646 646 646 ALA ALA A . n 
A 1 647 LEU 647 647 647 LEU LEU A . n 
A 1 648 HIS 648 648 648 HIS HIS A . n 
A 1 649 PHE 649 649 649 PHE PHE A . n 
A 1 650 ARG 650 650 650 ARG ARG A . n 
A 1 651 SER 651 651 651 SER SER A . n 
A 1 652 ASN 652 652 652 ASN ASN A . n 
A 1 653 GLN 653 653 653 GLN GLN A . n 
A 1 654 LEU 654 654 654 LEU LEU A . n 
A 1 655 PRO 655 655 655 PRO PRO A . n 
A 1 656 ASN 656 656 656 ASN ASN A . n 
A 1 657 GLN 657 657 657 GLN GLN A . n 
A 1 658 VAL 658 658 658 VAL VAL A . n 
A 1 659 SER 659 659 659 SER SER A . n 
A 1 660 ASP 660 660 660 ASP ASP A . n 
A 1 661 ALA 661 661 661 ALA ALA A . n 
A 1 662 MET 662 662 662 MET MET A . n 
A 1 663 HIS 663 663 663 HIS HIS A . n 
A 1 664 ALA 664 664 664 ALA ALA A . n 
A 1 665 TRP 665 665 665 TRP TRP A . n 
A 1 666 GLY 666 666 666 GLY GLY A . n 
A 1 667 ILE 667 667 667 ILE ILE A . n 
A 1 668 ASP 668 668 668 ASP ASP A . n 
A 1 669 GLY 669 669 669 GLY GLY A . n 
A 1 670 HIS 670 670 670 HIS HIS A . n 
A 1 671 GLN 671 671 671 GLN GLN A . n 
A 1 672 LEU 672 672 672 LEU LEU A . n 
A 1 673 THR 673 673 673 THR THR A . n 
A 1 674 VAL 674 674 674 VAL VAL A . n 
A 1 675 GLU 675 675 675 GLU GLU A . n 
A 1 676 ILE 676 676 676 ILE ILE A . n 
A 1 677 THR 677 677 677 THR THR A . n 
A 1 678 GLU 678 678 678 GLU GLU A . n 
A 1 679 SER 679 679 679 SER SER A . n 
A 1 680 MET 680 680 680 MET MET A . n 
A 1 681 MET 681 681 681 MET MET A . n 
A 1 682 MET 682 682 682 MET MET A . n 
A 1 683 GLU 683 683 683 GLU GLU A . n 
A 1 684 HIS 684 684 684 HIS HIS A . n 
A 1 685 ASP 685 685 685 ASP ASP A . n 
A 1 686 THR 686 686 686 THR THR A . n 
A 1 687 GLU 687 687 687 GLU GLU A . n 
A 1 688 ILE 688 688 688 ILE ILE A . n 
A 1 689 PHE 689 689 689 PHE PHE A . n 
A 1 690 LYS 690 690 690 LYS LYS A . n 
A 1 691 ARG 691 691 691 ARG ARG A . n 
A 1 692 ILE 692 692 692 ILE ILE A . n 
A 1 693 GLN 693 693 693 GLN GLN A . n 
A 1 694 ILE 694 694 694 ILE ILE A . n 
A 1 695 LEU 695 695 695 LEU LEU A . n 
A 1 696 ARG 696 696 696 ARG ARG A . n 
A 1 697 ASP 697 697 697 ASP ASP A . n 
A 1 698 MET 698 698 698 MET MET A . n 
A 1 699 GLY 699 699 699 GLY GLY A . n 
A 1 700 VAL 700 700 700 VAL VAL A . n 
A 1 701 GLY 701 701 701 GLY GLY A . n 
A 1 702 LEU 702 702 702 LEU LEU A . n 
A 1 703 SER 703 703 703 SER SER A . n 
A 1 704 VAL 704 704 704 VAL VAL A . n 
A 1 705 ASP 705 705 705 ASP ASP A . n 
A 1 706 ASP 706 706 706 ASP ASP A . n 
A 1 707 PHE 707 707 707 PHE PHE A . n 
A 1 708 GLY 708 708 708 GLY GLY A . n 
A 1 709 THR 709 709 709 THR THR A . n 
A 1 710 GLY 710 710 710 GLY GLY A . n 
A 1 711 PHE 711 711 711 PHE PHE A . n 
A 1 712 SER 712 712 712 SER SER A . n 
A 1 713 GLY 713 713 713 GLY GLY A . n 
A 1 714 LEU 714 714 714 LEU LEU A . n 
A 1 715 SER 715 715 715 SER SER A . n 
A 1 716 ARG 716 716 716 ARG ARG A . n 
A 1 717 LEU 717 717 717 LEU LEU A . n 
A 1 718 VAL 718 718 718 VAL VAL A . n 
A 1 719 SER 719 719 719 SER SER A . n 
A 1 720 LEU 720 720 720 LEU LEU A . n 
A 1 721 PRO 721 721 721 PRO PRO A . n 
A 1 722 VAL 722 722 722 VAL VAL A . n 
A 1 723 THR 723 723 723 THR THR A . n 
A 1 724 GLU 724 724 724 GLU GLU A . n 
A 1 725 ILE 725 725 725 ILE ILE A . n 
A 1 726 LYS 726 726 726 LYS LYS A . n 
A 1 727 ILE 727 727 727 ILE ILE A . n 
A 1 728 ASP 728 728 728 ASP ASP A . n 
A 1 729 LYS 729 729 729 LYS LYS A . n 
A 1 730 SER 730 730 730 SER SER A . n 
A 1 731 PHE 731 731 731 PHE PHE A . n 
A 1 732 VAL 732 732 732 VAL VAL A . n 
A 1 733 ASP 733 733 733 ASP ASP A . n 
A 1 734 ARG 734 734 734 ARG ARG A . n 
A 1 735 CYS 735 735 735 CYS CYS A . n 
A 1 736 LEU 736 736 736 LEU LEU A . n 
A 1 737 THR 737 737 737 THR THR A . n 
A 1 738 GLU 738 738 738 GLU GLU A . n 
A 1 739 LYS 739 739 739 LYS LYS A . n 
A 1 740 ARG 740 740 740 ARG ARG A . n 
A 1 741 ILE 741 741 741 ILE ILE A . n 
A 1 742 LEU 742 742 742 LEU LEU A . n 
A 1 743 ALA 743 743 743 ALA ALA A . n 
A 1 744 LEU 744 744 744 LEU LEU A . n 
A 1 745 LEU 745 745 745 LEU LEU A . n 
A 1 746 GLU 746 746 746 GLU GLU A . n 
A 1 747 ALA 747 747 747 ALA ALA A . n 
A 1 748 ILE 748 748 748 ILE ILE A . n 
A 1 749 THR 749 749 749 THR THR A . n 
A 1 750 SER 750 750 750 SER SER A . n 
A 1 751 ILE 751 751 751 ILE ILE A . n 
A 1 752 GLY 752 752 752 GLY GLY A . n 
A 1 753 GLN 753 753 753 GLN GLN A . n 
A 1 754 SER 754 754 754 SER SER A . n 
A 1 755 LEU 755 755 755 LEU LEU A . n 
A 1 756 ASN 756 756 756 ASN ASN A . n 
A 1 757 LEU 757 757 757 LEU LEU A . n 
A 1 758 THR 758 758 758 THR THR A . n 
A 1 759 VAL 759 759 759 VAL VAL A . n 
A 1 760 VAL 760 760 760 VAL VAL A . n 
A 1 761 ALA 761 761 761 ALA ALA A . n 
A 1 762 GLU 762 762 762 GLU GLU A . n 
A 1 763 GLY 763 763 763 GLY GLY A . n 
A 1 764 VAL 764 764 764 VAL VAL A . n 
A 1 765 GLU 765 765 765 GLU GLU A . n 
A 1 766 THR 766 766 766 THR THR A . n 
A 1 767 LYS 767 767 767 LYS LYS A . n 
A 1 768 GLU 768 768 768 GLU GLU A . n 
A 1 769 GLN 769 769 769 GLN GLN A . n 
A 1 770 PHE 770 770 770 PHE PHE A . n 
A 1 771 GLU 771 771 771 GLU GLU A . n 
A 1 772 MET 772 772 772 MET MET A . n 
A 1 773 LEU 773 773 773 LEU LEU A . n 
A 1 774 ARG 774 774 774 ARG ARG A . n 
A 1 775 LYS 775 775 775 LYS LYS A . n 
A 1 776 ILE 776 776 776 ILE ILE A . n 
A 1 777 HIS 777 777 777 HIS HIS A . n 
A 1 778 CYS 778 778 778 CYS CYS A . n 
A 1 779 ARG 779 779 779 ARG ARG A . n 
A 1 780 VAL 780 780 780 VAL VAL A . n 
A 1 781 ILE 781 781 781 ILE ILE A . n 
A 1 782 GLN 782 782 782 GLN GLN A . n 
A 1 783 GLY 783 783 783 GLY GLY A . n 
A 1 784 TYR 784 784 784 TYR TYR A . n 
A 1 785 PHE 785 785 785 PHE PHE A . n 
A 1 786 PHE 786 786 786 PHE PHE A . n 
A 1 787 SER 787 787 787 SER SER A . n 
A 1 788 ARG 788 788 788 ARG ARG A . n 
A 1 789 PRO 789 789 789 PRO PRO A . n 
A 1 790 LEU 790 790 790 LEU LEU A . n 
A 1 791 PRO 791 791 791 PRO PRO A . n 
A 1 792 ALA 792 792 792 ALA ALA A . n 
A 1 793 GLU 793 793 793 GLU GLU A . n 
A 1 794 GLU 794 794 794 GLU GLU A . n 
A 1 795 ILE 795 795 795 ILE ILE A . n 
A 1 796 PRO 796 796 796 PRO PRO A . n 
A 1 797 GLY 797 797 797 GLY GLY A . n 
A 1 798 TRP 798 798 798 TRP TRP A . n 
A 1 799 MET 799 799 799 MET MET A . n 
A 1 800 SER 800 800 800 SER SER A . n 
A 1 801 SER 801 801 801 SER SER A . n 
A 1 802 VAL 802 802 802 VAL VAL A . n 
A 1 803 LEU 803 803 803 LEU LEU A . n 
A 1 804 PRO 804 804 804 PRO PRO A . n 
A 1 805 LEU 805 805 805 LEU LEU A . n 
A 1 806 LYS 806 806 806 LYS LYS A . n 
A 1 807 ILE 807 807 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   ARG 2   2   ?   ?   ?   B . n 
B 1 3   GLN 3   3   ?   ?   ?   B . n 
B 1 4   ASP 4   4   ?   ?   ?   B . n 
B 1 5   ALA 5   5   ?   ?   ?   B . n 
B 1 6   GLU 6   6   ?   ?   ?   B . n 
B 1 7   VAL 7   7   ?   ?   ?   B . n 
B 1 8   ILE 8   8   ?   ?   ?   B . n 
B 1 9   MET 9   9   ?   ?   ?   B . n 
B 1 10  LYS 10  10  ?   ?   ?   B . n 
B 1 11  LEU 11  11  ?   ?   ?   B . n 
B 1 12  THR 12  12  ?   ?   ?   B . n 
B 1 13  ASP 13  13  ?   ?   ?   B . n 
B 1 14  ALA 14  14  ?   ?   ?   B . n 
B 1 15  ASP 15  15  ?   ?   ?   B . n 
B 1 16  SER 16  16  ?   ?   ?   B . n 
B 1 17  ALA 17  17  ?   ?   ?   B . n 
B 1 18  ALA 18  18  ?   ?   ?   B . n 
B 1 19  ASP 19  19  ?   ?   ?   B . n 
B 1 20  GLY 20  20  20  GLY GLY B . n 
B 1 21  ILE 21  21  21  ILE ILE B . n 
B 1 22  PHE 22  22  22  PHE PHE B . n 
B 1 23  PHE 23  23  23  PHE PHE B . n 
B 1 24  PRO 24  24  24  PRO PRO B . n 
B 1 25  ALA 25  25  25  ALA ALA B . n 
B 1 26  LEU 26  26  26  LEU LEU B . n 
B 1 27  GLU 27  27  27  GLU GLU B . n 
B 1 28  GLN 28  28  28  GLN GLN B . n 
B 1 29  ASN 29  29  29  ASN ASN B . n 
B 1 30  MET 30  30  30  MET MET B . n 
B 1 31  MET 31  31  31  MET MET B . n 
B 1 32  GLY 32  32  32  GLY GLY B . n 
B 1 33  ALA 33  33  33  ALA ALA B . n 
B 1 34  VAL 34  34  34  VAL VAL B . n 
B 1 35  LEU 35  35  35  LEU LEU B . n 
B 1 36  ILE 36  36  36  ILE ILE B . n 
B 1 37  ASN 37  37  37  ASN ASN B . n 
B 1 38  GLU 38  38  38  GLU GLU B . n 
B 1 39  ASN 39  39  39  ASN ASN B . n 
B 1 40  ASP 40  40  40  ASP ASP B . n 
B 1 41  GLU 41  41  41  GLU GLU B . n 
B 1 42  VAL 42  42  42  VAL VAL B . n 
B 1 43  MET 43  43  43  MET MET B . n 
B 1 44  PHE 44  44  44  PHE PHE B . n 
B 1 45  PHE 45  45  45  PHE PHE B . n 
B 1 46  ASN 46  46  46  ASN ASN B . n 
B 1 47  PRO 47  47  47  PRO PRO B . n 
B 1 48  ALA 48  48  48  ALA ALA B . n 
B 1 49  ALA 49  49  49  ALA ALA B . n 
B 1 50  GLU 50  50  50  GLU GLU B . n 
B 1 51  LYS 51  51  51  LYS LYS B . n 
B 1 52  LEU 52  52  52  LEU LEU B . n 
B 1 53  TRP 53  53  53  TRP TRP B . n 
B 1 54  GLY 54  54  54  GLY GLY B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  LYS 56  56  56  LYS LYS B . n 
B 1 57  ARG 57  57  57  ARG ARG B . n 
B 1 58  GLU 58  58  58  GLU GLU B . n 
B 1 59  GLU 59  59  59  GLU GLU B . n 
B 1 60  VAL 60  60  60  VAL VAL B . n 
B 1 61  ILE 61  61  61  ILE ILE B . n 
B 1 62  GLY 62  62  62  GLY GLY B . n 
B 1 63  ASN 63  63  63  ASN ASN B . n 
B 1 64  ASN 64  64  64  ASN ASN B . n 
B 1 65  ILE 65  65  65  ILE ILE B . n 
B 1 66  ASP 66  66  66  ASP ASP B . n 
B 1 67  MET 67  67  67  MET MET B . n 
B 1 68  LEU 68  68  68  LEU LEU B . n 
B 1 69  ILE 69  69  69  ILE ILE B . n 
B 1 70  PRO 70  70  70  PRO PRO B . n 
B 1 71  ARG 71  71  71  ARG ARG B . n 
B 1 72  ASP 72  72  72  ASP ASP B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ARG 74  74  74  ARG ARG B . n 
B 1 75  PRO 75  75  75  PRO PRO B . n 
B 1 76  ALA 76  76  76  ALA ALA B . n 
B 1 77  HIS 77  77  77  HIS HIS B . n 
B 1 78  PRO 78  78  78  PRO PRO B . n 
B 1 79  GLU 79  79  79  GLU GLU B . n 
B 1 80  TYR 80  80  80  TYR TYR B . n 
B 1 81  ILE 81  81  81  ILE ILE B . n 
B 1 82  ARG 82  82  82  ARG ARG B . n 
B 1 83  HIS 83  83  83  HIS HIS B . n 
B 1 84  ASN 84  84  84  ASN ASN B . n 
B 1 85  ARG 85  85  85  ARG ARG B . n 
B 1 86  GLU 86  86  86  GLU GLU B . n 
B 1 87  GLY 87  87  87  GLY GLY B . n 
B 1 88  GLY 88  88  88  GLY GLY B . n 
B 1 89  LYS 89  89  89  LYS LYS B . n 
B 1 90  ALA 90  90  90  ALA ALA B . n 
B 1 91  ARG 91  91  91  ARG ARG B . n 
B 1 92  VAL 92  92  92  VAL VAL B . n 
B 1 93  GLU 93  93  93  GLU GLU B . n 
B 1 94  GLY 94  94  94  GLY GLY B . n 
B 1 95  MET 95  95  95  MET MET B . n 
B 1 96  SER 96  96  96  SER SER B . n 
B 1 97  ALA 97  97  97  ALA ALA B . n 
B 1 98  GLU 98  98  98  GLU GLU B . n 
B 1 99  LEU 99  99  99  LEU LEU B . n 
B 1 100 GLN 100 100 100 GLN GLN B . n 
B 1 101 LEU 101 101 101 LEU LEU B . n 
B 1 102 GLU 102 102 102 GLU GLU B . n 
B 1 103 LYS 103 103 103 LYS LYS B . n 
B 1 104 LYS 104 104 104 LYS LYS B . n 
B 1 105 ASP 105 105 105 ASP ASP B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 SER 107 107 107 SER SER B . n 
B 1 108 LYS 108 108 108 LYS LYS B . n 
B 1 109 ILE 109 109 109 ILE ILE B . n 
B 1 110 TRP 110 110 110 TRP TRP B . n 
B 1 111 THR 111 111 111 THR THR B . n 
B 1 112 ARG 112 112 112 ARG ARG B . n 
B 1 113 PHE 113 113 113 PHE PHE B . n 
B 1 114 ALA 114 114 114 ALA ALA B . n 
B 1 115 LEU 115 115 115 LEU LEU B . n 
B 1 116 SER 116 116 116 SER SER B . n 
B 1 117 LYS 117 117 117 LYS LYS B . n 
B 1 118 VAL 118 118 118 VAL VAL B . n 
B 1 119 SER 119 119 119 SER SER B . n 
B 1 120 ALA 120 120 120 ALA ALA B . n 
B 1 121 GLU 121 121 121 GLU GLU B . n 
B 1 122 GLY 122 122 122 GLY GLY B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 VAL 124 124 124 VAL VAL B . n 
B 1 125 TYR 125 125 125 TYR TYR B . n 
B 1 126 TYR 126 126 126 TYR TYR B . n 
B 1 127 LEU 127 127 127 LEU LEU B . n 
B 1 128 ALA 128 128 128 ALA ALA B . n 
B 1 129 LEU 129 129 129 LEU LEU B . n 
B 1 130 VAL 130 130 130 VAL VAL B . n 
B 1 131 ARG 131 131 131 ARG ARG B . n 
B 1 132 ASP 132 132 132 ASP ASP B . n 
B 1 133 ALA 133 133 133 ALA ALA B . n 
B 1 134 SER 134 134 134 SER SER B . n 
B 1 135 VAL 135 135 135 VAL VAL B . n 
B 1 136 GLU 136 136 136 GLU GLU B . n 
B 1 137 MET 137 137 137 MET MET B . n 
B 1 138 ALA 138 138 138 ALA ALA B . n 
B 1 139 GLN 139 139 139 GLN GLN B . n 
B 1 140 LYS 140 140 140 LYS LYS B . n 
B 1 141 GLU 141 141 141 GLU GLU B . n 
B 1 142 GLN 142 142 142 GLN GLN B . n 
B 1 143 THR 143 143 143 THR THR B . n 
B 1 144 ARG 144 144 144 ARG ARG B . n 
B 1 145 GLN 145 145 145 GLN GLN B . n 
B 1 146 LEU 146 146 146 LEU LEU B . n 
B 1 147 ILE 147 147 147 ILE ILE B . n 
B 1 148 ILE 148 148 148 ILE ILE B . n 
B 1 149 ALA 149 149 149 ALA ALA B . n 
B 1 150 VAL 150 150 150 VAL VAL B . n 
B 1 151 ASP 151 151 151 ASP ASP B . n 
B 1 152 HIS 152 152 152 HIS HIS B . n 
B 1 153 LEU 153 153 153 LEU LEU B . n 
B 1 154 ASP 154 154 154 ASP ASP B . n 
B 1 155 ARG 155 155 155 ARG ARG B . n 
B 1 156 PRO 156 156 156 PRO PRO B . n 
B 1 157 VAL 157 157 157 VAL VAL B . n 
B 1 158 ILE 158 158 158 ILE ILE B . n 
B 1 159 VAL 159 159 159 VAL VAL B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 ASP 161 161 161 ASP ASP B . n 
B 1 162 PRO 162 162 162 PRO PRO B . n 
B 1 163 GLU 163 163 163 GLU GLU B . n 
B 1 164 ARG 164 164 164 ARG ARG B . n 
B 1 165 HIS 165 165 165 HIS HIS B . n 
B 1 166 ILE 166 166 166 ILE ILE B . n 
B 1 167 VAL 167 167 167 VAL VAL B . n 
B 1 168 GLN 168 168 168 GLN GLN B . n 
B 1 169 CYS 169 169 169 CYS CYS B . n 
B 1 170 ASN 170 170 170 ASN ASN B . n 
B 1 171 ARG 171 171 171 ARG ARG B . n 
B 1 172 ALA 172 172 172 ALA ALA B . n 
B 1 173 PHE 173 173 173 PHE PHE B . n 
B 1 174 THR 174 174 174 THR THR B . n 
B 1 175 GLU 175 175 175 GLU GLU B . n 
B 1 176 MET 176 176 176 MET MET B . n 
B 1 177 PHE 177 177 177 PHE PHE B . n 
B 1 178 GLY 178 178 178 GLY GLY B . n 
B 1 179 TYR 179 179 179 TYR TYR B . n 
B 1 180 CYS 180 180 180 CYS CYS B . n 
B 1 181 ILE 181 181 181 ILE ILE B . n 
B 1 182 SER 182 182 182 SER SER B . n 
B 1 183 GLU 183 183 183 GLU GLU B . n 
B 1 184 ALA 184 184 184 ALA ALA B . n 
B 1 185 SER 185 185 185 SER SER B . n 
B 1 186 GLY 186 186 186 GLY GLY B . n 
B 1 187 MET 187 187 187 MET MET B . n 
B 1 188 GLN 188 188 188 GLN GLN B . n 
B 1 189 PRO 189 189 189 PRO PRO B . n 
B 1 190 ASP 190 190 190 ASP ASP B . n 
B 1 191 THR 191 191 191 THR THR B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 LEU 193 193 193 LEU LEU B . n 
B 1 194 ASN 194 194 194 ASN ASN B . n 
B 1 195 THR 195 195 195 THR THR B . n 
B 1 196 PRO 196 196 196 PRO PRO B . n 
B 1 197 GLU 197 197 197 GLU GLU B . n 
B 1 198 PHE 198 198 198 PHE PHE B . n 
B 1 199 PRO 199 199 199 PRO PRO B . n 
B 1 200 ALA 200 200 200 ALA ALA B . n 
B 1 201 ASP 201 201 201 ASP ASP B . n 
B 1 202 ASN 202 202 202 ASN ASN B . n 
B 1 203 ARG 203 203 203 ARG ARG B . n 
B 1 204 ILE 204 204 204 ILE ILE B . n 
B 1 205 ARG 205 205 205 ARG ARG B . n 
B 1 206 LEU 206 206 206 LEU LEU B . n 
B 1 207 GLN 207 207 207 GLN GLN B . n 
B 1 208 GLN 208 208 208 GLN GLN B . n 
B 1 209 LEU 209 209 209 LEU LEU B . n 
B 1 210 LEU 210 210 210 LEU LEU B . n 
B 1 211 TRP 211 211 211 TRP TRP B . n 
B 1 212 LYS 212 212 212 LYS LYS B . n 
B 1 213 THR 213 213 213 THR THR B . n 
B 1 214 ALA 214 214 214 ALA ALA B . n 
B 1 215 ARG 215 215 215 ARG ARG B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 GLN 217 217 217 GLN GLN B . n 
B 1 218 ASP 218 218 218 ASP ASP B . n 
B 1 219 GLU 219 219 219 GLU GLU B . n 
B 1 220 PHE 220 220 220 PHE PHE B . n 
B 1 221 LEU 221 221 221 LEU LEU B . n 
B 1 222 LEU 222 222 222 LEU LEU B . n 
B 1 223 LEU 223 223 223 LEU LEU B . n 
B 1 224 THR 224 224 224 THR THR B . n 
B 1 225 ARG 225 225 225 ARG ARG B . n 
B 1 226 THR 226 226 226 THR THR B . n 
B 1 227 GLY 227 227 227 GLY GLY B . n 
B 1 228 GLU 228 228 228 GLU GLU B . n 
B 1 229 LYS 229 229 229 LYS LYS B . n 
B 1 230 ILE 230 230 230 ILE ILE B . n 
B 1 231 TRP 231 231 231 TRP TRP B . n 
B 1 232 ILE 232 232 232 ILE ILE B . n 
B 1 233 LYS 233 233 233 LYS LYS B . n 
B 1 234 ALA 234 234 234 ALA ALA B . n 
B 1 235 SER 235 235 235 SER SER B . n 
B 1 236 ILE 236 236 236 ILE ILE B . n 
B 1 237 SER 237 237 237 SER SER B . n 
B 1 238 PRO 238 238 238 PRO PRO B . n 
B 1 239 VAL 239 239 239 VAL VAL B . n 
B 1 240 TYR 240 240 240 TYR TYR B . n 
B 1 241 ASP 241 241 241 ASP ASP B . n 
B 1 242 VAL 242 242 242 VAL VAL B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 ALA 244 244 244 ALA ALA B . n 
B 1 245 HIS 245 245 245 HIS HIS B . n 
B 1 246 LEU 246 246 246 LEU LEU B . n 
B 1 247 GLN 247 247 247 GLN GLN B . n 
B 1 248 ASN 248 248 248 ASN ASN B . n 
B 1 249 LEU 249 249 249 LEU LEU B . n 
B 1 250 VAL 250 250 250 VAL VAL B . n 
B 1 251 MET 251 251 251 MET MET B . n 
B 1 252 THR 252 252 252 THR THR B . n 
B 1 253 PHE 253 253 253 PHE PHE B . n 
B 1 254 SER 254 254 254 SER SER B . n 
B 1 255 ASP 255 255 255 ASP ASP B . n 
B 1 256 ILE 256 256 256 ILE ILE B . n 
B 1 257 THR 257 257 257 THR THR B . n 
B 1 258 GLU 258 258 258 GLU GLU B . n 
B 1 259 GLU 259 259 259 GLU GLU B . n 
B 1 260 ARG 260 260 260 ARG ARG B . n 
B 1 261 GLN 261 261 261 GLN GLN B . n 
B 1 262 ILE 262 262 262 ILE ILE B . n 
B 1 263 ARG 263 263 263 ARG ARG B . n 
B 1 264 GLN 264 264 264 GLN GLN B . n 
B 1 265 LEU 265 265 265 LEU LEU B . n 
B 1 266 GLU 266 266 266 GLU GLU B . n 
B 1 267 GLY 267 267 267 GLY GLY B . n 
B 1 268 ASN 268 268 268 ASN ASN B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 LEU 270 270 270 LEU LEU B . n 
B 1 271 ALA 271 271 271 ALA ALA B . n 
B 1 272 ALA 272 272 272 ALA ALA B . n 
B 1 273 MET 273 273 273 MET MET B . n 
B 1 274 CYS 274 274 274 CYS CYS B . n 
B 1 275 SER 275 275 275 SER SER B . n 
B 1 276 SER 276 276 276 SER SER B . n 
B 1 277 PRO 277 277 277 PRO PRO B . n 
B 1 278 PRO 278 278 278 PRO PRO B . n 
B 1 279 PHE 279 279 279 PHE PHE B . n 
B 1 280 HIS 280 280 280 HIS HIS B . n 
B 1 281 GLU 281 281 281 GLU GLU B . n 
B 1 282 MET 282 282 282 MET MET B . n 
B 1 283 GLY 283 283 283 GLY GLY B . n 
B 1 284 GLU 284 284 284 GLU GLU B . n 
B 1 285 ILE 285 285 285 ILE ILE B . n 
B 1 286 ILE 286 286 286 ILE ILE B . n 
B 1 287 CYS 287 287 287 CYS CYS B . n 
B 1 288 ARG 288 288 288 ARG ARG B . n 
B 1 289 ASN 289 289 289 ASN ASN B . n 
B 1 290 ILE 290 290 290 ILE ILE B . n 
B 1 291 GLU 291 291 291 GLU GLU B . n 
B 1 292 SER 292 292 292 SER SER B . n 
B 1 293 VAL 293 293 293 VAL VAL B . n 
B 1 294 LEU 294 294 294 LEU LEU B . n 
B 1 295 ASN 295 295 295 ASN ASN B . n 
B 1 296 GLU 296 296 296 GLU GLU B . n 
B 1 297 SER 297 297 297 SER SER B . n 
B 1 298 HIS 298 298 298 HIS HIS B . n 
B 1 299 VAL 299 299 299 VAL VAL B . n 
B 1 300 SER 300 300 300 SER SER B . n 
B 1 301 LEU 301 301 301 LEU LEU B . n 
B 1 302 PHE 302 302 302 PHE PHE B . n 
B 1 303 ALA 303 303 303 ALA ALA B . n 
B 1 304 LEU 304 304 304 LEU LEU B . n 
B 1 305 ARG 305 305 305 ARG ARG B . n 
B 1 306 ASN 306 306 306 ASN ASN B . n 
B 1 307 GLY 307 307 307 GLY GLY B . n 
B 1 308 MET 308 308 308 MET MET B . n 
B 1 309 PRO 309 309 309 PRO PRO B . n 
B 1 310 ILE 310 310 310 ILE ILE B . n 
B 1 311 HIS 311 311 311 HIS HIS B . n 
B 1 312 TRP 312 312 312 TRP TRP B . n 
B 1 313 ALA 313 313 313 ALA ALA B . n 
B 1 314 SER 314 314 314 SER SER B . n 
B 1 315 SER 315 315 315 SER SER B . n 
B 1 316 SER 316 316 316 SER SER B . n 
B 1 317 HIS 317 317 317 HIS HIS B . n 
B 1 318 GLY 318 318 318 GLY GLY B . n 
B 1 319 ALA 319 319 319 ALA ALA B . n 
B 1 320 GLU 320 320 320 GLU GLU B . n 
B 1 321 ILE 321 321 321 ILE ILE B . n 
B 1 322 GLN 322 322 322 GLN GLN B . n 
B 1 323 ASN 323 323 323 ASN ASN B . n 
B 1 324 ALA 324 324 324 ALA ALA B . n 
B 1 325 GLN 325 325 325 GLN GLN B . n 
B 1 326 SER 326 326 326 SER SER B . n 
B 1 327 TRP 327 327 327 TRP TRP B . n 
B 1 328 SER 328 328 328 SER SER B . n 
B 1 329 ALA 329 329 329 ALA ALA B . n 
B 1 330 THR 330 330 330 THR THR B . n 
B 1 331 ILE 331 331 331 ILE ILE B . n 
B 1 332 ARG 332 332 332 ARG ARG B . n 
B 1 333 GLN 333 333 333 GLN GLN B . n 
B 1 334 ARG 334 334 334 ARG ARG B . n 
B 1 335 ASP 335 335 335 ASP ASP B . n 
B 1 336 GLY 336 336 336 GLY GLY B . n 
B 1 337 ALA 337 337 337 ALA ALA B . n 
B 1 338 PRO 338 338 338 PRO PRO B . n 
B 1 339 ALA 339 339 339 ALA ALA B . n 
B 1 340 GLY 340 340 340 GLY GLY B . n 
B 1 341 ILE 341 341 341 ILE ILE B . n 
B 1 342 LEU 342 342 342 LEU LEU B . n 
B 1 343 GLN 343 343 343 GLN GLN B . n 
B 1 344 ILE 344 344 344 ILE ILE B . n 
B 1 345 LYS 345 345 345 LYS LYS B . n 
B 1 346 THR 346 346 346 THR THR B . n 
B 1 347 SER 347 347 347 SER SER B . n 
B 1 348 SER 348 348 348 SER SER B . n 
B 1 349 GLY 349 349 349 GLY GLY B . n 
B 1 350 ALA 350 350 350 ALA ALA B . n 
B 1 351 GLU 351 351 351 GLU GLU B . n 
B 1 352 THR 352 352 352 THR THR B . n 
B 1 353 SER 353 353 353 SER SER B . n 
B 1 354 ALA 354 354 354 ALA ALA B . n 
B 1 355 PHE 355 355 355 PHE PHE B . n 
B 1 356 ILE 356 356 356 ILE ILE B . n 
B 1 357 GLU 357 357 357 GLU GLU B . n 
B 1 358 ARG 358 358 358 ARG ARG B . n 
B 1 359 VAL 359 359 359 VAL VAL B . n 
B 1 360 ALA 360 360 360 ALA ALA B . n 
B 1 361 ASP 361 361 361 ASP ASP B . n 
B 1 362 ILE 362 362 362 ILE ILE B . n 
B 1 363 SER 363 363 363 SER SER B . n 
B 1 364 GLN 364 364 364 GLN GLN B . n 
B 1 365 HIS 365 365 365 HIS HIS B . n 
B 1 366 MET 366 366 366 MET MET B . n 
B 1 367 ALA 367 367 367 ALA ALA B . n 
B 1 368 ALA 368 368 368 ALA ALA B . n 
B 1 369 LEU 369 369 369 LEU LEU B . n 
B 1 370 ALA 370 370 370 ALA ALA B . n 
B 1 371 LEU 371 371 371 LEU LEU B . n 
B 1 372 GLU 372 372 372 GLU GLU B . n 
B 1 373 GLN 373 373 373 GLN GLN B . n 
B 1 374 GLU 374 374 374 GLU GLU B . n 
B 1 375 LYS 375 375 375 LYS LYS B . n 
B 1 376 SER 376 376 376 SER SER B . n 
B 1 377 ARG 377 377 377 ARG ARG B . n 
B 1 378 GLN 378 378 378 GLN GLN B . n 
B 1 379 HIS 379 379 379 HIS HIS B . n 
B 1 380 ILE 380 380 380 ILE ILE B . n 
B 1 381 GLU 381 381 381 GLU GLU B . n 
B 1 382 GLN 382 382 382 GLN GLN B . n 
B 1 383 LEU 383 383 383 LEU LEU B . n 
B 1 384 ILE 384 384 384 ILE ILE B . n 
B 1 385 GLN 385 385 385 GLN GLN B . n 
B 1 386 PHE 386 386 386 PHE PHE B . n 
B 1 387 ASP 387 387 387 ASP ASP B . n 
B 1 388 PRO 388 388 388 PRO PRO B . n 
B 1 389 MET 389 389 389 MET MET B . n 
B 1 390 THR 390 390 390 THR THR B . n 
B 1 391 GLY 391 391 391 GLY GLY B . n 
B 1 392 LEU 392 392 392 LEU LEU B . n 
B 1 393 PRO 393 393 393 PRO PRO B . n 
B 1 394 ASN 394 394 394 ASN ASN B . n 
B 1 395 ARG 395 395 395 ARG ARG B . n 
B 1 396 ASN 396 396 396 ASN ASN B . n 
B 1 397 ASN 397 397 397 ASN ASN B . n 
B 1 398 LEU 398 398 398 LEU LEU B . n 
B 1 399 HIS 399 399 399 HIS HIS B . n 
B 1 400 ASN 400 400 400 ASN ASN B . n 
B 1 401 TYR 401 401 401 TYR TYR B . n 
B 1 402 LEU 402 402 402 LEU LEU B . n 
B 1 403 ASP 403 403 403 ASP ASP B . n 
B 1 404 ASP 404 404 404 ASP ASP B . n 
B 1 405 LEU 405 405 405 LEU LEU B . n 
B 1 406 VAL 406 406 406 VAL VAL B . n 
B 1 407 ASP 407 407 407 ASP ASP B . n 
B 1 408 LYS 408 408 408 LYS LYS B . n 
B 1 409 ALA 409 409 409 ALA ALA B . n 
B 1 410 VAL 410 410 410 VAL VAL B . n 
B 1 411 SER 411 411 411 SER SER B . n 
B 1 412 PRO 412 412 412 PRO PRO B . n 
B 1 413 VAL 413 413 413 VAL VAL B . n 
B 1 414 VAL 414 414 414 VAL VAL B . n 
B 1 415 TYR 415 415 415 TYR TYR B . n 
B 1 416 LEU 416 416 416 LEU LEU B . n 
B 1 417 ILE 417 417 417 ILE ILE B . n 
B 1 418 GLY 418 418 418 GLY GLY B . n 
B 1 419 VAL 419 419 419 VAL VAL B . n 
B 1 420 ASP 420 420 420 ASP ASP B . n 
B 1 421 HIS 421 421 421 HIS HIS B . n 
B 1 422 ILE 422 422 422 ILE ILE B . n 
B 1 423 GLN 423 423 423 GLN GLN B . n 
B 1 424 ASP 424 424 424 ASP ASP B . n 
B 1 425 VAL 425 425 425 VAL VAL B . n 
B 1 426 ILE 426 426 426 ILE ILE B . n 
B 1 427 ASP 427 427 427 ASP ASP B . n 
B 1 428 SER 428 428 428 SER SER B . n 
B 1 429 LEU 429 429 429 LEU LEU B . n 
B 1 430 GLY 430 430 430 GLY GLY B . n 
B 1 431 TYR 431 431 431 TYR TYR B . n 
B 1 432 ALA 432 432 432 ALA ALA B . n 
B 1 433 TRP 433 433 433 TRP TRP B . n 
B 1 434 ALA 434 434 434 ALA ALA B . n 
B 1 435 ASP 435 435 435 ASP ASP B . n 
B 1 436 GLN 436 436 436 GLN GLN B . n 
B 1 437 ALA 437 437 437 ALA ALA B . n 
B 1 438 LEU 438 438 438 LEU LEU B . n 
B 1 439 LEU 439 439 439 LEU LEU B . n 
B 1 440 GLU 440 440 440 GLU GLU B . n 
B 1 441 VAL 441 441 441 VAL VAL B . n 
B 1 442 VAL 442 442 442 VAL VAL B . n 
B 1 443 ASN 443 443 443 ASN ASN B . n 
B 1 444 ARG 444 444 444 ARG ARG B . n 
B 1 445 PHE 445 445 445 PHE PHE B . n 
B 1 446 ARG 446 446 446 ARG ARG B . n 
B 1 447 GLU 447 447 447 GLU GLU B . n 
B 1 448 LYS 448 448 448 LYS LYS B . n 
B 1 449 LEU 449 449 449 LEU LEU B . n 
B 1 450 LYS 450 450 450 LYS LYS B . n 
B 1 451 PRO 451 451 451 PRO PRO B . n 
B 1 452 ASP 452 452 452 ASP ASP B . n 
B 1 453 GLN 453 453 453 GLN GLN B . n 
B 1 454 TYR 454 454 454 TYR TYR B . n 
B 1 455 LEU 455 455 455 LEU LEU B . n 
B 1 456 CYS 456 456 456 CYS CYS B . n 
B 1 457 ARG 457 457 457 ARG ARG B . n 
B 1 458 ILE 458 458 458 ILE ILE B . n 
B 1 459 GLU 459 459 459 GLU GLU B . n 
B 1 460 GLY 460 460 460 GLY GLY B . n 
B 1 461 THR 461 461 461 THR THR B . n 
B 1 462 GLN 462 462 462 GLN GLN B . n 
B 1 463 PHE 463 463 463 PHE PHE B . n 
B 1 464 VAL 464 464 464 VAL VAL B . n 
B 1 465 LEU 465 465 465 LEU LEU B . n 
B 1 466 VAL 466 466 466 VAL VAL B . n 
B 1 467 SER 467 467 467 SER SER B . n 
B 1 468 LEU 468 468 468 LEU LEU B . n 
B 1 469 GLU 469 469 469 GLU GLU B . n 
B 1 470 ASN 470 470 470 ASN ASN B . n 
B 1 471 ASP 471 471 471 ASP ASP B . n 
B 1 472 VAL 472 472 472 VAL VAL B . n 
B 1 473 SER 473 473 473 SER SER B . n 
B 1 474 ASN 474 474 474 ASN ASN B . n 
B 1 475 ILE 475 475 475 ILE ILE B . n 
B 1 476 THR 476 476 476 THR THR B . n 
B 1 477 GLN 477 477 477 GLN GLN B . n 
B 1 478 ILE 478 478 478 ILE ILE B . n 
B 1 479 ALA 479 479 479 ALA ALA B . n 
B 1 480 ASP 480 480 480 ASP ASP B . n 
B 1 481 GLU 481 481 481 GLU GLU B . n 
B 1 482 LEU 482 482 482 LEU LEU B . n 
B 1 483 ARG 483 483 483 ARG ARG B . n 
B 1 484 ASN 484 484 484 ASN ASN B . n 
B 1 485 VAL 485 485 485 VAL VAL B . n 
B 1 486 VAL 486 486 486 VAL VAL B . n 
B 1 487 SER 487 487 487 SER SER B . n 
B 1 488 LYS 488 488 488 LYS LYS B . n 
B 1 489 PRO 489 489 489 PRO PRO B . n 
B 1 490 ILE 490 490 490 ILE ILE B . n 
B 1 491 MET 491 491 491 MET MET B . n 
B 1 492 ILE 492 492 492 ILE ILE B . n 
B 1 493 ASP 493 493 493 ASP ASP B . n 
B 1 494 ASP 494 494 494 ASP ASP B . n 
B 1 495 LYS 495 495 495 LYS LYS B . n 
B 1 496 PRO 496 496 496 PRO PRO B . n 
B 1 497 PHE 497 497 497 PHE PHE B . n 
B 1 498 PRO 498 498 498 PRO PRO B . n 
B 1 499 LEU 499 499 499 LEU LEU B . n 
B 1 500 THR 500 500 500 THR THR B . n 
B 1 501 LEU 501 501 501 LEU LEU B . n 
B 1 502 SER 502 502 502 SER SER B . n 
B 1 503 ILE 503 503 503 ILE ILE B . n 
B 1 504 GLY 504 504 504 GLY GLY B . n 
B 1 505 ILE 505 505 505 ILE ILE B . n 
B 1 506 SER 506 506 506 SER SER B . n 
B 1 507 TYR 507 507 507 TYR TYR B . n 
B 1 508 ASP 508 508 508 ASP ASP B . n 
B 1 509 LEU 509 509 509 LEU LEU B . n 
B 1 510 GLY 510 510 510 GLY GLY B . n 
B 1 511 LYS 511 511 511 LYS LYS B . n 
B 1 512 ASN 512 512 512 ASN ASN B . n 
B 1 513 ARG 513 513 513 ARG ARG B . n 
B 1 514 ASP 514 514 514 ASP ASP B . n 
B 1 515 TYR 515 515 515 TYR TYR B . n 
B 1 516 LEU 516 516 516 LEU LEU B . n 
B 1 517 LEU 517 517 517 LEU LEU B . n 
B 1 518 SER 518 518 518 SER SER B . n 
B 1 519 THR 519 519 519 THR THR B . n 
B 1 520 ALA 520 520 520 ALA ALA B . n 
B 1 521 HIS 521 521 521 HIS HIS B . n 
B 1 522 ASN 522 522 522 ASN ASN B . n 
B 1 523 ALA 523 523 523 ALA ALA B . n 
B 1 524 MET 524 524 524 MET MET B . n 
B 1 525 ASP 525 525 525 ASP ASP B . n 
B 1 526 TYR 526 526 526 TYR TYR B . n 
B 1 527 ILE 527 527 527 ILE ILE B . n 
B 1 528 ARG 528 528 528 ARG ARG B . n 
B 1 529 LYS 529 529 529 LYS LYS B . n 
B 1 530 ASN 530 530 530 ASN ASN B . n 
B 1 531 GLY 531 531 531 GLY GLY B . n 
B 1 532 GLY 532 532 532 GLY GLY B . n 
B 1 533 ASN 533 533 533 ASN ASN B . n 
B 1 534 GLY 534 534 534 GLY GLY B . n 
B 1 535 TRP 535 535 535 TRP TRP B . n 
B 1 536 GLN 536 536 536 GLN GLN B . n 
B 1 537 PHE 537 537 537 PHE PHE B . n 
B 1 538 PHE 538 538 538 PHE PHE B . n 
B 1 539 SER 539 539 539 SER SER B . n 
B 1 540 PRO 540 540 540 PRO PRO B . n 
B 1 541 ALA 541 541 541 ALA ALA B . n 
B 1 542 MET 542 542 542 MET MET B . n 
B 1 543 ASN 543 543 543 ASN ASN B . n 
B 1 544 GLU 544 544 544 GLU GLU B . n 
B 1 545 MET 545 545 545 MET MET B . n 
B 1 546 VAL 546 546 546 VAL VAL B . n 
B 1 547 LYS 547 547 547 LYS LYS B . n 
B 1 548 GLU 548 548 548 GLU GLU B . n 
B 1 549 ARG 549 549 549 ARG ARG B . n 
B 1 550 LEU 550 550 550 LEU LEU B . n 
B 1 551 VAL 551 551 551 VAL VAL B . n 
B 1 552 LEU 552 552 552 LEU LEU B . n 
B 1 553 GLY 553 553 553 GLY GLY B . n 
B 1 554 ALA 554 554 554 ALA ALA B . n 
B 1 555 ALA 555 555 555 ALA ALA B . n 
B 1 556 LEU 556 556 556 LEU LEU B . n 
B 1 557 LYS 557 557 557 LYS LYS B . n 
B 1 558 GLU 558 558 558 GLU GLU B . n 
B 1 559 ALA 559 559 559 ALA ALA B . n 
B 1 560 ILE 560 560 560 ILE ILE B . n 
B 1 561 SER 561 561 561 SER SER B . n 
B 1 562 ASN 562 562 562 ASN ASN B . n 
B 1 563 ASN 563 563 563 ASN ASN B . n 
B 1 564 GLN 564 564 564 GLN GLN B . n 
B 1 565 LEU 565 565 565 LEU LEU B . n 
B 1 566 LYS 566 566 566 LYS LYS B . n 
B 1 567 LEU 567 567 567 LEU LEU B . n 
B 1 568 VAL 568 568 568 VAL VAL B . n 
B 1 569 TYR 569 569 569 TYR TYR B . n 
B 1 570 GLN 570 570 570 GLN GLN B . n 
B 1 571 PRO 571 571 571 PRO PRO B . n 
B 1 572 GLN 572 572 572 GLN GLN B . n 
B 1 573 ILE 573 573 573 ILE ILE B . n 
B 1 574 PHE 574 574 574 PHE PHE B . n 
B 1 575 ALA 575 575 575 ALA ALA B . n 
B 1 576 GLU 576 576 576 GLU GLU B . n 
B 1 577 THR 577 577 577 THR THR B . n 
B 1 578 GLY 578 578 578 GLY GLY B . n 
B 1 579 GLU 579 579 579 GLU GLU B . n 
B 1 580 LEU 580 580 580 LEU LEU B . n 
B 1 581 TYR 581 581 581 TYR TYR B . n 
B 1 582 GLY 582 582 582 GLY GLY B . n 
B 1 583 ILE 583 583 583 ILE ILE B . n 
B 1 584 GLU 584 584 584 GLU GLU B . n 
B 1 585 ALA 585 585 585 ALA ALA B . n 
B 1 586 LEU 586 586 586 LEU LEU B . n 
B 1 587 ALA 587 587 587 ALA ALA B . n 
B 1 588 ARG 588 588 588 ARG ARG B . n 
B 1 589 TRP 589 589 589 TRP TRP B . n 
B 1 590 HIS 590 590 590 HIS HIS B . n 
B 1 591 ASP 591 591 591 ASP ASP B . n 
B 1 592 PRO 592 592 592 PRO PRO B . n 
B 1 593 LEU 593 593 593 LEU LEU B . n 
B 1 594 HIS 594 594 594 HIS HIS B . n 
B 1 595 GLY 595 595 595 GLY GLY B . n 
B 1 596 HIS 596 596 596 HIS HIS B . n 
B 1 597 VAL 597 597 597 VAL VAL B . n 
B 1 598 PRO 598 598 598 PRO PRO B . n 
B 1 599 PRO 599 599 599 PRO PRO B . n 
B 1 600 SER 600 600 600 SER SER B . n 
B 1 601 ARG 601 601 601 ARG ARG B . n 
B 1 602 PHE 602 602 602 PHE PHE B . n 
B 1 603 ILE 603 603 603 ILE ILE B . n 
B 1 604 PRO 604 604 604 PRO PRO B . n 
B 1 605 LEU 605 605 605 LEU LEU B . n 
B 1 606 ALA 606 606 606 ALA ALA B . n 
B 1 607 GLU 607 607 607 GLU GLU B . n 
B 1 608 GLU 608 608 608 GLU GLU B . n 
B 1 609 ILE 609 609 609 ILE ILE B . n 
B 1 610 GLY 610 610 610 GLY GLY B . n 
B 1 611 GLU 611 611 611 GLU GLU B . n 
B 1 612 ILE 612 612 612 ILE ILE B . n 
B 1 613 GLU 613 613 613 GLU GLU B . n 
B 1 614 ASN 614 614 614 ASN ASN B . n 
B 1 615 ILE 615 615 615 ILE ILE B . n 
B 1 616 GLY 616 616 616 GLY GLY B . n 
B 1 617 ARG 617 617 617 ARG ARG B . n 
B 1 618 TRP 618 618 618 TRP TRP B . n 
B 1 619 VAL 619 619 619 VAL VAL B . n 
B 1 620 ILE 620 620 620 ILE ILE B . n 
B 1 621 ALA 621 621 621 ALA ALA B . n 
B 1 622 GLU 622 622 622 GLU GLU B . n 
B 1 623 ALA 623 623 623 ALA ALA B . n 
B 1 624 CYS 624 624 624 CYS CYS B . n 
B 1 625 ARG 625 625 625 ARG ARG B . n 
B 1 626 GLN 626 626 626 GLN GLN B . n 
B 1 627 LEU 627 627 627 LEU LEU B . n 
B 1 628 ALA 628 628 628 ALA ALA B . n 
B 1 629 GLU 629 629 629 GLU GLU B . n 
B 1 630 TRP 630 630 630 TRP TRP B . n 
B 1 631 ARG 631 631 631 ARG ARG B . n 
B 1 632 SER 632 632 632 SER SER B . n 
B 1 633 GLN 633 633 633 GLN GLN B . n 
B 1 634 ASN 634 634 634 ASN ASN B . n 
B 1 635 ILE 635 635 635 ILE ILE B . n 
B 1 636 HIS 636 636 636 HIS HIS B . n 
B 1 637 ILE 637 637 637 ILE ILE B . n 
B 1 638 PRO 638 638 638 PRO PRO B . n 
B 1 639 ALA 639 639 639 ALA ALA B . n 
B 1 640 LEU 640 640 640 LEU LEU B . n 
B 1 641 SER 641 641 641 SER SER B . n 
B 1 642 VAL 642 642 642 VAL VAL B . n 
B 1 643 ASN 643 643 643 ASN ASN B . n 
B 1 644 LEU 644 644 644 LEU LEU B . n 
B 1 645 SER 645 645 645 SER SER B . n 
B 1 646 ALA 646 646 646 ALA ALA B . n 
B 1 647 LEU 647 647 647 LEU LEU B . n 
B 1 648 HIS 648 648 648 HIS HIS B . n 
B 1 649 PHE 649 649 649 PHE PHE B . n 
B 1 650 ARG 650 650 650 ARG ARG B . n 
B 1 651 SER 651 651 651 SER SER B . n 
B 1 652 ASN 652 652 652 ASN ASN B . n 
B 1 653 GLN 653 653 653 GLN GLN B . n 
B 1 654 LEU 654 654 654 LEU LEU B . n 
B 1 655 PRO 655 655 655 PRO PRO B . n 
B 1 656 ASN 656 656 656 ASN ASN B . n 
B 1 657 GLN 657 657 657 GLN GLN B . n 
B 1 658 VAL 658 658 658 VAL VAL B . n 
B 1 659 SER 659 659 659 SER SER B . n 
B 1 660 ASP 660 660 660 ASP ASP B . n 
B 1 661 ALA 661 661 661 ALA ALA B . n 
B 1 662 MET 662 662 662 MET MET B . n 
B 1 663 HIS 663 663 663 HIS HIS B . n 
B 1 664 ALA 664 664 664 ALA ALA B . n 
B 1 665 TRP 665 665 665 TRP TRP B . n 
B 1 666 GLY 666 666 666 GLY GLY B . n 
B 1 667 ILE 667 667 667 ILE ILE B . n 
B 1 668 ASP 668 668 668 ASP ASP B . n 
B 1 669 GLY 669 669 669 GLY GLY B . n 
B 1 670 HIS 670 670 670 HIS HIS B . n 
B 1 671 GLN 671 671 671 GLN GLN B . n 
B 1 672 LEU 672 672 672 LEU LEU B . n 
B 1 673 THR 673 673 673 THR THR B . n 
B 1 674 VAL 674 674 674 VAL VAL B . n 
B 1 675 GLU 675 675 675 GLU GLU B . n 
B 1 676 ILE 676 676 676 ILE ILE B . n 
B 1 677 THR 677 677 677 THR THR B . n 
B 1 678 GLU 678 678 678 GLU GLU B . n 
B 1 679 SER 679 679 679 SER SER B . n 
B 1 680 MET 680 680 680 MET MET B . n 
B 1 681 MET 681 681 681 MET MET B . n 
B 1 682 MET 682 682 682 MET MET B . n 
B 1 683 GLU 683 683 683 GLU GLU B . n 
B 1 684 HIS 684 684 684 HIS HIS B . n 
B 1 685 ASP 685 685 685 ASP ASP B . n 
B 1 686 THR 686 686 686 THR THR B . n 
B 1 687 GLU 687 687 687 GLU GLU B . n 
B 1 688 ILE 688 688 688 ILE ILE B . n 
B 1 689 PHE 689 689 689 PHE PHE B . n 
B 1 690 LYS 690 690 690 LYS LYS B . n 
B 1 691 ARG 691 691 691 ARG ARG B . n 
B 1 692 ILE 692 692 692 ILE ILE B . n 
B 1 693 GLN 693 693 693 GLN GLN B . n 
B 1 694 ILE 694 694 694 ILE ILE B . n 
B 1 695 LEU 695 695 695 LEU LEU B . n 
B 1 696 ARG 696 696 696 ARG ARG B . n 
B 1 697 ASP 697 697 697 ASP ASP B . n 
B 1 698 MET 698 698 698 MET MET B . n 
B 1 699 GLY 699 699 699 GLY GLY B . n 
B 1 700 VAL 700 700 700 VAL VAL B . n 
B 1 701 GLY 701 701 701 GLY GLY B . n 
B 1 702 LEU 702 702 702 LEU LEU B . n 
B 1 703 SER 703 703 703 SER SER B . n 
B 1 704 VAL 704 704 704 VAL VAL B . n 
B 1 705 ASP 705 705 705 ASP ASP B . n 
B 1 706 ASP 706 706 706 ASP ASP B . n 
B 1 707 PHE 707 707 707 PHE PHE B . n 
B 1 708 GLY 708 708 708 GLY GLY B . n 
B 1 709 THR 709 709 709 THR THR B . n 
B 1 710 GLY 710 710 710 GLY GLY B . n 
B 1 711 PHE 711 711 711 PHE PHE B . n 
B 1 712 SER 712 712 712 SER SER B . n 
B 1 713 GLY 713 713 713 GLY GLY B . n 
B 1 714 LEU 714 714 714 LEU LEU B . n 
B 1 715 SER 715 715 715 SER SER B . n 
B 1 716 ARG 716 716 716 ARG ARG B . n 
B 1 717 LEU 717 717 717 LEU LEU B . n 
B 1 718 VAL 718 718 718 VAL VAL B . n 
B 1 719 SER 719 719 719 SER SER B . n 
B 1 720 LEU 720 720 720 LEU LEU B . n 
B 1 721 PRO 721 721 721 PRO PRO B . n 
B 1 722 VAL 722 722 722 VAL VAL B . n 
B 1 723 THR 723 723 723 THR THR B . n 
B 1 724 GLU 724 724 724 GLU GLU B . n 
B 1 725 ILE 725 725 725 ILE ILE B . n 
B 1 726 LYS 726 726 726 LYS LYS B . n 
B 1 727 ILE 727 727 727 ILE ILE B . n 
B 1 728 ASP 728 728 728 ASP ASP B . n 
B 1 729 LYS 729 729 729 LYS LYS B . n 
B 1 730 SER 730 730 730 SER SER B . n 
B 1 731 PHE 731 731 731 PHE PHE B . n 
B 1 732 VAL 732 732 732 VAL VAL B . n 
B 1 733 ASP 733 733 733 ASP ASP B . n 
B 1 734 ARG 734 734 734 ARG ARG B . n 
B 1 735 CYS 735 735 735 CYS CYS B . n 
B 1 736 LEU 736 736 736 LEU LEU B . n 
B 1 737 THR 737 737 737 THR THR B . n 
B 1 738 GLU 738 738 738 GLU GLU B . n 
B 1 739 LYS 739 739 739 LYS LYS B . n 
B 1 740 ARG 740 740 740 ARG ARG B . n 
B 1 741 ILE 741 741 741 ILE ILE B . n 
B 1 742 LEU 742 742 742 LEU LEU B . n 
B 1 743 ALA 743 743 743 ALA ALA B . n 
B 1 744 LEU 744 744 744 LEU LEU B . n 
B 1 745 LEU 745 745 745 LEU LEU B . n 
B 1 746 GLU 746 746 746 GLU GLU B . n 
B 1 747 ALA 747 747 747 ALA ALA B . n 
B 1 748 ILE 748 748 748 ILE ILE B . n 
B 1 749 THR 749 749 749 THR THR B . n 
B 1 750 SER 750 750 750 SER SER B . n 
B 1 751 ILE 751 751 751 ILE ILE B . n 
B 1 752 GLY 752 752 752 GLY GLY B . n 
B 1 753 GLN 753 753 753 GLN GLN B . n 
B 1 754 SER 754 754 754 SER SER B . n 
B 1 755 LEU 755 755 755 LEU LEU B . n 
B 1 756 ASN 756 756 756 ASN ASN B . n 
B 1 757 LEU 757 757 757 LEU LEU B . n 
B 1 758 THR 758 758 758 THR THR B . n 
B 1 759 VAL 759 759 759 VAL VAL B . n 
B 1 760 VAL 760 760 760 VAL VAL B . n 
B 1 761 ALA 761 761 761 ALA ALA B . n 
B 1 762 GLU 762 762 762 GLU GLU B . n 
B 1 763 GLY 763 763 763 GLY GLY B . n 
B 1 764 VAL 764 764 764 VAL VAL B . n 
B 1 765 GLU 765 765 765 GLU GLU B . n 
B 1 766 THR 766 766 766 THR THR B . n 
B 1 767 LYS 767 767 767 LYS LYS B . n 
B 1 768 GLU 768 768 768 GLU GLU B . n 
B 1 769 GLN 769 769 769 GLN GLN B . n 
B 1 770 PHE 770 770 770 PHE PHE B . n 
B 1 771 GLU 771 771 771 GLU GLU B . n 
B 1 772 MET 772 772 772 MET MET B . n 
B 1 773 LEU 773 773 773 LEU LEU B . n 
B 1 774 ARG 774 774 774 ARG ARG B . n 
B 1 775 LYS 775 775 775 LYS LYS B . n 
B 1 776 ILE 776 776 776 ILE ILE B . n 
B 1 777 HIS 777 777 777 HIS HIS B . n 
B 1 778 CYS 778 778 778 CYS CYS B . n 
B 1 779 ARG 779 779 779 ARG ARG B . n 
B 1 780 VAL 780 780 780 VAL VAL B . n 
B 1 781 ILE 781 781 781 ILE ILE B . n 
B 1 782 GLN 782 782 782 GLN GLN B . n 
B 1 783 GLY 783 783 783 GLY GLY B . n 
B 1 784 TYR 784 784 784 TYR TYR B . n 
B 1 785 PHE 785 785 785 PHE PHE B . n 
B 1 786 PHE 786 786 786 PHE PHE B . n 
B 1 787 SER 787 787 787 SER SER B . n 
B 1 788 ARG 788 788 788 ARG ARG B . n 
B 1 789 PRO 789 789 789 PRO PRO B . n 
B 1 790 LEU 790 790 790 LEU LEU B . n 
B 1 791 PRO 791 791 791 PRO PRO B . n 
B 1 792 ALA 792 792 792 ALA ALA B . n 
B 1 793 GLU 793 793 793 GLU GLU B . n 
B 1 794 GLU 794 794 794 GLU GLU B . n 
B 1 795 ILE 795 795 795 ILE ILE B . n 
B 1 796 PRO 796 796 796 PRO PRO B . n 
B 1 797 GLY 797 797 797 GLY GLY B . n 
B 1 798 TRP 798 798 798 TRP TRP B . n 
B 1 799 MET 799 799 799 MET MET B . n 
B 1 800 SER 800 800 800 SER SER B . n 
B 1 801 SER 801 801 801 SER SER B . n 
B 1 802 VAL 802 802 802 VAL VAL B . n 
B 1 803 LEU 803 803 803 LEU LEU B . n 
B 1 804 PRO 804 804 804 PRO PRO B . n 
B 1 805 LEU 805 805 805 LEU LEU B . n 
B 1 806 LYS 806 806 806 LYS LYS B . n 
B 1 807 ILE 807 807 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        HEM 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   HEM 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 2 HEM 1 901 2135 HEM HEM A . 
D 2 HEM 1 901 2135 HEM HEM B . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BGV 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BGV 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BGV 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BGV 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 12860 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.633 ? 17454 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 6.471 ? 1714  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.046 ? 1930  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 2272  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BGV 
_struct.title                        'DosP R97A straight form' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BGV 
_struct_keywords.text            'Heme, DosP, Phosphodiesterase, c-di-GMP, OXYGEN BINDING' 
_struct_keywords.pdbx_keywords   'OXYGEN BINDING' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    DOSP_ECOLI 
_struct_ref.pdbx_db_accession          P76129 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKLWGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGG
KARVEGMSRELQLEKKDGSKIWTRFALSKVSAEGKVYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRTGEKIWIKASISPVYDVLAHLQN
LVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGEIICRNIESVLNESHVSLFALRNGMPIHWASSSHGAEIQNAQSWS
ATIRQRDGAPAGILQIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHNYLDDLVDK
AVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRIEGTQFVLVSLENDVSNITQIADELRNVVSK
PIMIDDKPFPLTLSIGISYDLGKNRDYLLSTAHNAMDYIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLV
YQPQIFAETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRSQNIHIPALSVNLSALH
FRSNQLPNQVSDAMHAWGIDGHQLTVEITESMMMEHDTEIFKRIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKID
KSFVDRCLTEKRILALLEAITSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLKI
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BGV A 9 ? 807 ? P76129 1 ? 799 ? 9 807 
2 1 9BGV B 9 ? 807 ? P76129 1 ? 799 ? 9 807 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BGV MET A 1   ? UNP P76129 ?   ?   'expression tag'      1   1  
1 9BGV ARG A 2   ? UNP P76129 ?   ?   'expression tag'      2   2  
1 9BGV GLN A 3   ? UNP P76129 ?   ?   'expression tag'      3   3  
1 9BGV ASP A 4   ? UNP P76129 ?   ?   'expression tag'      4   4  
1 9BGV ALA A 5   ? UNP P76129 ?   ?   'expression tag'      5   5  
1 9BGV GLU A 6   ? UNP P76129 ?   ?   'expression tag'      6   6  
1 9BGV VAL A 7   ? UNP P76129 ?   ?   'expression tag'      7   7  
1 9BGV ILE A 8   ? UNP P76129 ?   ?   'expression tag'      8   8  
1 9BGV SER A 16  ? UNP P76129 ASN 8   conflict              16  9  
1 9BGV ALA A 97  ? UNP P76129 ARG 89  'engineered mutation' 97  10 
1 9BGV THR A 195 ? UNP P76129 ILE 187 conflict              195 11 
2 9BGV MET B 1   ? UNP P76129 ?   ?   'expression tag'      1   12 
2 9BGV ARG B 2   ? UNP P76129 ?   ?   'expression tag'      2   13 
2 9BGV GLN B 3   ? UNP P76129 ?   ?   'expression tag'      3   14 
2 9BGV ASP B 4   ? UNP P76129 ?   ?   'expression tag'      4   15 
2 9BGV ALA B 5   ? UNP P76129 ?   ?   'expression tag'      5   16 
2 9BGV GLU B 6   ? UNP P76129 ?   ?   'expression tag'      6   17 
2 9BGV VAL B 7   ? UNP P76129 ?   ?   'expression tag'      7   18 
2 9BGV ILE B 8   ? UNP P76129 ?   ?   'expression tag'      8   19 
2 9BGV SER B 16  ? UNP P76129 ASN 8   conflict              16  20 
2 9BGV ALA B 97  ? UNP P76129 ARG 89  'engineered mutation' 97  21 
2 9BGV THR B 195 ? UNP P76129 ILE 187 conflict              195 22 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
loop_
_pdbx_struct_assembly_auth_evidence.id 
_pdbx_struct_assembly_auth_evidence.assembly_id 
_pdbx_struct_assembly_auth_evidence.experimental_support 
_pdbx_struct_assembly_auth_evidence.details 
1 1 'electron microscopy' 'not applicable' 
2 1 'gel filtration'      ?                
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ILE A 21  ? GLN A 28  ? ILE A 21  GLN A 28  1 ? 8  
HELX_P HELX_P2  AA2 ASN A 46  ? GLY A 54  ? ASN A 46  GLY A 54  1 ? 9  
HELX_P HELX_P3  AA3 LYS A 56  ? ILE A 61  ? LYS A 56  ILE A 61  1 ? 6  
HELX_P HELX_P4  AA4 ASN A 64  ? ILE A 69  ? ASN A 64  ILE A 69  5 ? 6  
HELX_P HELX_P5  AA5 PRO A 70  ? ARG A 74  ? PRO A 70  ARG A 74  5 ? 5  
HELX_P HELX_P6  AA6 ALA A 76  ? GLY A 88  ? ALA A 76  GLY A 88  1 ? 13 
HELX_P HELX_P7  AA7 ALA A 133 ? LEU A 153 ? ALA A 133 LEU A 153 1 ? 21 
HELX_P HELX_P8  AA8 ASN A 170 ? GLY A 178 ? ASN A 170 GLY A 178 1 ? 9  
HELX_P HELX_P9  AA9 ASP A 201 ? LEU A 210 ? ASP A 201 LEU A 210 1 ? 10 
HELX_P HELX_P10 AB1 ILE A 256 ? CYS A 274 ? ILE A 256 CYS A 274 1 ? 19 
HELX_P HELX_P11 AB2 PRO A 278 ? LEU A 294 ? PRO A 278 LEU A 294 1 ? 17 
HELX_P HELX_P12 AB3 THR A 352 ? GLU A 381 ? THR A 352 GLU A 381 1 ? 30 
HELX_P HELX_P13 AB4 ASN A 394 ? LYS A 408 ? ASN A 394 LYS A 408 1 ? 15 
HELX_P HELX_P14 AB5 HIS A 421 ? LEU A 429 ? HIS A 421 LEU A 429 1 ? 9  
HELX_P HELX_P15 AB6 GLY A 430 ? LYS A 448 ? GLY A 430 LYS A 448 1 ? 19 
HELX_P HELX_P16 AB7 ASP A 471 ? VAL A 485 ? ASP A 471 VAL A 485 1 ? 15 
HELX_P HELX_P17 AB8 ASP A 514 ? GLY A 531 ? ASP A 514 GLY A 531 1 ? 18 
HELX_P HELX_P18 AB9 MET A 542 ? ASN A 562 ? MET A 542 ASN A 562 1 ? 21 
HELX_P HELX_P19 AC1 PRO A 598 ? GLY A 610 ? PRO A 598 GLY A 610 1 ? 13 
HELX_P HELX_P20 AC2 GLU A 611 ? SER A 632 ? GLU A 611 SER A 632 1 ? 22 
HELX_P HELX_P21 AC3 GLN A 653 ? GLY A 666 ? GLN A 653 GLY A 666 1 ? 14 
HELX_P HELX_P22 AC4 THR A 677 ? MET A 682 ? THR A 677 MET A 682 1 ? 6  
HELX_P HELX_P23 AC5 GLU A 687 ? GLY A 699 ? GLU A 687 GLY A 699 1 ? 13 
HELX_P HELX_P24 AC6 ASP A 728 ? ASP A 733 ? ASP A 728 ASP A 733 1 ? 6  
HELX_P HELX_P25 AC7 ARG A 740 ? ASN A 756 ? ARG A 740 ASN A 756 1 ? 17 
HELX_P HELX_P26 AC8 THR A 766 ? ILE A 776 ? THR A 766 ILE A 776 1 ? 11 
HELX_P HELX_P27 AC9 PRO A 791 ? GLU A 793 ? PRO A 791 GLU A 793 5 ? 3  
HELX_P HELX_P28 AD1 GLU A 794 ? VAL A 802 ? GLU A 794 VAL A 802 1 ? 9  
HELX_P HELX_P29 AD2 PHE B 22  ? GLN B 28  ? PHE B 22  GLN B 28  1 ? 7  
HELX_P HELX_P30 AD3 ASN B 46  ? GLY B 54  ? ASN B 46  GLY B 54  1 ? 9  
HELX_P HELX_P31 AD4 LYS B 56  ? ILE B 61  ? LYS B 56  ILE B 61  1 ? 6  
HELX_P HELX_P32 AD5 ALA B 76  ? GLY B 88  ? ALA B 76  GLY B 88  1 ? 13 
HELX_P HELX_P33 AD6 ALA B 133 ? HIS B 152 ? ALA B 133 HIS B 152 1 ? 20 
HELX_P HELX_P34 AD7 ASN B 170 ? GLY B 178 ? ASN B 170 GLY B 178 1 ? 9  
HELX_P HELX_P35 AD8 CYS B 180 ? SER B 185 ? CYS B 180 SER B 185 1 ? 6  
HELX_P HELX_P36 AD9 GLN B 188 ? LEU B 193 ? GLN B 188 LEU B 193 1 ? 6  
HELX_P HELX_P37 AE1 ASP B 201 ? GLN B 208 ? ASP B 201 GLN B 208 1 ? 8  
HELX_P HELX_P38 AE2 ILE B 256 ? CYS B 274 ? ILE B 256 CYS B 274 1 ? 19 
HELX_P HELX_P39 AE3 PRO B 278 ? LEU B 294 ? PRO B 278 LEU B 294 1 ? 17 
HELX_P HELX_P40 AE4 THR B 352 ? GLN B 382 ? THR B 352 GLN B 382 1 ? 31 
HELX_P HELX_P41 AE5 ASN B 394 ? LYS B 408 ? ASN B 394 LYS B 408 1 ? 15 
HELX_P HELX_P42 AE6 ILE B 422 ? LEU B 429 ? ILE B 422 LEU B 429 1 ? 8  
HELX_P HELX_P43 AE7 GLY B 430 ? LEU B 449 ? GLY B 430 LEU B 449 1 ? 20 
HELX_P HELX_P44 AE8 ASP B 471 ? VAL B 485 ? ASP B 471 VAL B 485 1 ? 15 
HELX_P HELX_P45 AE9 ASN B 512 ? GLY B 531 ? ASN B 512 GLY B 531 1 ? 20 
HELX_P HELX_P46 AF1 SER B 539 ? ASN B 563 ? SER B 539 ASN B 563 1 ? 25 
HELX_P HELX_P47 AF2 PRO B 598 ? GLY B 610 ? PRO B 598 GLY B 610 1 ? 13 
HELX_P HELX_P48 AF3 GLU B 611 ? GLN B 633 ? GLU B 611 GLN B 633 1 ? 23 
HELX_P HELX_P49 AF4 LEU B 654 ? GLY B 666 ? LEU B 654 GLY B 666 1 ? 13 
HELX_P HELX_P50 AF5 ASP B 668 ? HIS B 670 ? ASP B 668 HIS B 670 5 ? 3  
HELX_P HELX_P51 AF6 ASP B 685 ? LYS B 690 ? ASP B 685 LYS B 690 1 ? 6  
HELX_P HELX_P52 AF7 ARG B 691 ? GLY B 699 ? ARG B 691 GLY B 699 1 ? 9  
HELX_P HELX_P53 AF8 LEU B 714 ? SER B 719 ? LEU B 714 SER B 719 1 ? 6  
HELX_P HELX_P54 AF9 ASP B 728 ? ASP B 733 ? ASP B 728 ASP B 733 1 ? 6  
HELX_P HELX_P55 AG1 GLU B 738 ? ASN B 756 ? GLU B 738 ASN B 756 1 ? 19 
HELX_P HELX_P56 AG2 THR B 766 ? HIS B 777 ? THR B 766 HIS B 777 1 ? 12 
HELX_P HELX_P57 AG3 GLU B 794 ? VAL B 802 ? GLU B 794 VAL B 802 1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_conn.id                            metalc1 
_struct_conn.conn_type_id                  metalc 
_struct_conn.pdbx_leaving_atom_flag        ? 
_struct_conn.pdbx_PDB_id                   ? 
_struct_conn.ptnr1_label_asym_id           B 
_struct_conn.ptnr1_label_comp_id           HIS 
_struct_conn.ptnr1_label_seq_id            77 
_struct_conn.ptnr1_label_atom_id           NE2 
_struct_conn.pdbx_ptnr1_label_alt_id       ? 
_struct_conn.pdbx_ptnr1_PDB_ins_code       ? 
_struct_conn.pdbx_ptnr1_standard_comp_id   ? 
_struct_conn.ptnr1_symmetry                1_555 
_struct_conn.ptnr2_label_asym_id           D 
_struct_conn.ptnr2_label_comp_id           HEM 
_struct_conn.ptnr2_label_seq_id            . 
_struct_conn.ptnr2_label_atom_id           FE 
_struct_conn.pdbx_ptnr2_label_alt_id       ? 
_struct_conn.pdbx_ptnr2_PDB_ins_code       ? 
_struct_conn.ptnr1_auth_asym_id            B 
_struct_conn.ptnr1_auth_comp_id            HIS 
_struct_conn.ptnr1_auth_seq_id             77 
_struct_conn.ptnr2_auth_asym_id            B 
_struct_conn.ptnr2_auth_comp_id            HEM 
_struct_conn.ptnr2_auth_seq_id             901 
_struct_conn.ptnr2_symmetry                1_555 
_struct_conn.pdbx_ptnr3_label_atom_id      ? 
_struct_conn.pdbx_ptnr3_label_seq_id       ? 
_struct_conn.pdbx_ptnr3_label_comp_id      ? 
_struct_conn.pdbx_ptnr3_label_asym_id      ? 
_struct_conn.pdbx_ptnr3_label_alt_id       ? 
_struct_conn.pdbx_ptnr3_PDB_ins_code       ? 
_struct_conn.details                       ? 
_struct_conn.pdbx_dist_value               2.195 
_struct_conn.pdbx_value_order              ? 
_struct_conn.pdbx_role                     ? 
# 
_struct_conn_type.id          metalc 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NA ? D HEM . ? B HEM 901 ? 1_555 97.8  ? 
2  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NB ? D HEM . ? B HEM 901 ? 1_555 55.8  ? 
3  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NB ? D HEM . ? B HEM 901 ? 1_555 90.5  ? 
4  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 85.0  ? 
5  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 177.0 ? 
6  NB  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 NC ? D HEM . ? B HEM 901 ? 1_555 90.3  ? 
7  NE2 ? B HIS 77 ? B HIS 77  ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 126.0 ? 
8  NA  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 89.9  ? 
9  NB  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 178.0 ? 
10 NC  ? D HEM .  ? B HEM 901 ? 1_555 FE ? D HEM . ? B HEM 901 ? 1_555 ND ? D HEM . ? B HEM 901 ? 1_555 89.2  ? 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 LEU 803 A . ? LEU 803 A PRO 804 A ? PRO 804 A 1 -5.21 
2 LEU 803 B . ? LEU 803 B PRO 804 B ? PRO 804 B 1 -9.45 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 5  ? 
AA2 ? 5  ? 
AA3 ? 4  ? 
AA4 ? 5  ? 
AA5 ? 2  ? 
AA6 ? 6  ? 
AA7 ? 2  ? 
AA8 ? 5  ? 
AA9 ? 4  ? 
AB1 ? 4  ? 
AB2 ? 4  ? 
AB3 ? 5  ? 
AB4 ? 2  ? 
AB5 ? 10 ? 
AB6 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2  ? anti-parallel 
AA1 2 3  ? anti-parallel 
AA1 3 4  ? anti-parallel 
AA1 4 5  ? anti-parallel 
AA2 1 2  ? anti-parallel 
AA2 2 3  ? anti-parallel 
AA2 3 4  ? anti-parallel 
AA2 4 5  ? anti-parallel 
AA3 1 2  ? anti-parallel 
AA3 2 3  ? anti-parallel 
AA3 3 4  ? anti-parallel 
AA4 1 2  ? anti-parallel 
AA4 2 3  ? anti-parallel 
AA4 3 4  ? anti-parallel 
AA4 4 5  ? parallel      
AA5 1 2  ? anti-parallel 
AA6 1 2  ? parallel      
AA6 2 3  ? anti-parallel 
AA6 3 4  ? anti-parallel 
AA6 4 5  ? parallel      
AA6 5 6  ? parallel      
AA7 1 2  ? parallel      
AA8 1 2  ? anti-parallel 
AA8 2 3  ? anti-parallel 
AA8 3 4  ? anti-parallel 
AA8 4 5  ? anti-parallel 
AA9 1 2  ? anti-parallel 
AA9 2 3  ? anti-parallel 
AA9 3 4  ? anti-parallel 
AB1 1 2  ? anti-parallel 
AB1 2 3  ? anti-parallel 
AB1 3 4  ? anti-parallel 
AB2 1 2  ? anti-parallel 
AB2 2 3  ? anti-parallel 
AB2 3 4  ? anti-parallel 
AB3 1 2  ? anti-parallel 
AB3 2 3  ? anti-parallel 
AB3 3 4  ? anti-parallel 
AB3 4 5  ? parallel      
AB4 1 2  ? anti-parallel 
AB5 1 2  ? anti-parallel 
AB5 2 3  ? anti-parallel 
AB5 3 4  ? parallel      
AB5 4 5  ? parallel      
AB5 5 6  ? parallel      
AB5 6 7  ? parallel      
AB5 7 8  ? parallel      
AB5 8 9  ? parallel      
AB5 9 10 ? anti-parallel 
AB6 1 2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  VAL A 42  ? PHE A 45  ? VAL A 42  PHE A 45  
AA1 2  GLY A 32  ? ILE A 36  ? GLY A 32  ILE A 36  
AA1 3  LYS A 123 ? ASP A 132 ? LYS A 123 ASP A 132 
AA1 4  LYS A 108 ? ALA A 120 ? LYS A 108 ALA A 120 
AA1 5  LEU A 99  ? GLU A 102 ? LEU A 99  GLU A 102 
AA2 1  ILE A 166 ? CYS A 169 ? ILE A 166 CYS A 169 
AA2 2  VAL A 157 ? LEU A 160 ? VAL A 157 LEU A 160 
AA2 3  LEU A 246 ? THR A 252 ? LEU A 246 THR A 252 
AA2 4  LYS A 229 ? TYR A 240 ? LYS A 229 TYR A 240 
AA2 5  ASP A 216 ? LEU A 223 ? ASP A 216 LEU A 223 
AA3 1  MET A 308 ? SER A 314 ? MET A 308 SER A 314 
AA3 2  HIS A 298 ? ARG A 305 ? HIS A 298 ARG A 305 
AA3 3  PRO A 338 ? THR A 346 ? PRO A 338 THR A 346 
AA3 4  GLN A 325 ? ARG A 332 ? GLN A 325 ARG A 332 
AA4 1  TYR A 454 ? GLU A 459 ? TYR A 454 GLU A 459 
AA4 2  GLN A 462 ? SER A 467 ? GLN A 462 SER A 467 
AA4 3  VAL A 413 ? ASP A 420 ? VAL A 413 ASP A 420 
AA4 4  THR A 500 ? GLY A 504 ? THR A 500 GLY A 504 
AA4 5  GLY A 534 ? GLN A 536 ? GLY A 534 GLN A 536 
AA5 1  LYS A 566 ? VAL A 568 ? LYS A 566 VAL A 568 
AA5 2  LEU A 586 ? ARG A 588 ? LEU A 586 ARG A 588 
AA6 1  LEU A 640 ? SER A 641 ? LEU A 640 SER A 641 
AA6 2  LEU A 580 ? GLU A 584 ? LEU A 580 GLU A 584 
AA6 3  PRO A 571 ? PHE A 574 ? PRO A 571 PHE A 574 
AA6 4  VAL A 780 ? GLN A 782 ? VAL A 780 GLN A 782 
AA6 5  THR A 758 ? GLU A 762 ? THR A 758 GLU A 762 
AA6 6  GLU A 724 ? LYS A 726 ? GLU A 724 LYS A 726 
AA7 1  THR A 673 ? ILE A 676 ? THR A 673 ILE A 676 
AA7 2  GLY A 701 ? VAL A 704 ? GLY A 701 VAL A 704 
AA8 1  VAL B 42  ? PHE B 45  ? VAL B 42  PHE B 45  
AA8 2  GLY B 32  ? ILE B 36  ? GLY B 32  ILE B 36  
AA8 3  LYS B 123 ? ASP B 132 ? LYS B 123 ASP B 132 
AA8 4  LYS B 108 ? PHE B 113 ? LYS B 108 PHE B 113 
AA8 5  LEU B 99  ? GLU B 102 ? LEU B 99  GLU B 102 
AA9 1  VAL B 42  ? PHE B 45  ? VAL B 42  PHE B 45  
AA9 2  GLY B 32  ? ILE B 36  ? GLY B 32  ILE B 36  
AA9 3  LYS B 123 ? ASP B 132 ? LYS B 123 ASP B 132 
AA9 4  SER B 116 ? ALA B 120 ? SER B 116 ALA B 120 
AB1 1  ILE B 158 ? LEU B 160 ? ILE B 158 LEU B 160 
AB1 2  LEU B 246 ? ASP B 255 ? LEU B 246 ASP B 255 
AB1 3  LYS B 229 ? TYR B 240 ? LYS B 229 TYR B 240 
AB1 4  GLU B 219 ? LEU B 223 ? GLU B 219 LEU B 223 
AB2 1  MET B 308 ? SER B 314 ? MET B 308 SER B 314 
AB2 2  SER B 297 ? ARG B 305 ? SER B 297 ARG B 305 
AB2 3  PRO B 338 ? SER B 347 ? PRO B 338 SER B 347 
AB2 4  ALA B 324 ? ARG B 332 ? ALA B 324 ARG B 332 
AB3 1  TYR B 454 ? GLU B 459 ? TYR B 454 GLU B 459 
AB3 2  GLN B 462 ? SER B 467 ? GLN B 462 SER B 467 
AB3 3  VAL B 413 ? ASP B 420 ? VAL B 413 ASP B 420 
AB3 4  THR B 500 ? TYR B 507 ? THR B 500 TYR B 507 
AB3 5  GLY B 534 ? PHE B 537 ? GLY B 534 PHE B 537 
AB4 1  ILE B 490 ? MET B 491 ? ILE B 490 MET B 491 
AB4 2  PRO B 496 ? PHE B 497 ? PRO B 496 PHE B 497 
AB5 1  LEU B 790 ? PRO B 791 ? LEU B 790 PRO B 791 
AB5 2  LYS B 566 ? PHE B 574 ? LYS B 566 PHE B 574 
AB5 3  VAL B 780 ? GLY B 783 ? VAL B 780 GLY B 783 
AB5 4  THR B 758 ? VAL B 764 ? THR B 758 VAL B 764 
AB5 5  GLU B 724 ? ILE B 727 ? GLU B 724 ILE B 727 
AB5 6  SER B 703 ? VAL B 704 ? SER B 703 VAL B 704 
AB5 7  LEU B 672 ? ILE B 676 ? LEU B 672 ILE B 676 
AB5 8  LEU B 640 ? VAL B 642 ? LEU B 640 VAL B 642 
AB5 9  LEU B 580 ? ARG B 588 ? LEU B 580 ARG B 588 
AB5 10 LYS B 566 ? PHE B 574 ? LYS B 566 PHE B 574 
AB6 1  HIS B 590 ? ASP B 591 ? HIS B 590 ASP B 591 
AB6 2  GLY B 595 ? HIS B 596 ? GLY B 595 HIS B 596 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2  O MET A 43  ? O MET A 43  N LEU A 35  ? N LEU A 35  
AA1 2 3  N VAL A 34  ? N VAL A 34  O ALA A 128 ? O ALA A 128 
AA1 3 4  O TYR A 125 ? O TYR A 125 N VAL A 118 ? N VAL A 118 
AA1 4 5  O THR A 111 ? O THR A 111 N LEU A 99  ? N LEU A 99  
AA2 1 2  O VAL A 167 ? O VAL A 167 N VAL A 159 ? N VAL A 159 
AA2 2 3  N ILE A 158 ? N ILE A 158 O MET A 251 ? O MET A 251 
AA2 3 4  O ASN A 248 ? O ASN A 248 N VAL A 239 ? N VAL A 239 
AA2 4 5  O ILE A 230 ? O ILE A 230 N LEU A 222 ? N LEU A 222 
AA3 1 2  O ILE A 310 ? O ILE A 310 N ALA A 303 ? N ALA A 303 
AA3 2 3  N HIS A 298 ? N HIS A 298 O LYS A 345 ? O LYS A 345 
AA3 3 4  O ALA A 339 ? O ALA A 339 N ILE A 331 ? N ILE A 331 
AA4 1 2  N GLU A 459 ? N GLU A 459 O GLN A 462 ? O GLN A 462 
AA4 2 3  O SER A 467 ? O SER A 467 N VAL A 413 ? N VAL A 413 
AA4 3 4  N ASP A 420 ? N ASP A 420 O THR A 500 ? O THR A 500 
AA4 4 5  N LEU A 501 ? N LEU A 501 O GLY A 534 ? O GLY A 534 
AA5 1 2  N LYS A 566 ? N LYS A 566 O ARG A 588 ? O ARG A 588 
AA6 1 2  O SER A 641 ? O SER A 641 N ILE A 583 ? N ILE A 583 
AA6 2 3  O TYR A 581 ? O TYR A 581 N GLN A 572 ? N GLN A 572 
AA6 3 4  N ILE A 573 ? N ILE A 573 O ILE A 781 ? O ILE A 781 
AA6 4 5  O VAL A 780 ? O VAL A 780 N ALA A 761 ? N ALA A 761 
AA6 5 6  O VAL A 760 ? O VAL A 760 N ILE A 725 ? N ILE A 725 
AA7 1 2  N VAL A 674 ? N VAL A 674 O GLY A 701 ? O GLY A 701 
AA8 1 2  O MET B 43  ? O MET B 43  N LEU B 35  ? N LEU B 35  
AA8 2 3  N VAL B 34  ? N VAL B 34  O ALA B 128 ? O ALA B 128 
AA8 3 4  O ARG B 131 ? O ARG B 131 N ARG B 112 ? N ARG B 112 
AA8 4 5  O ILE B 109 ? O ILE B 109 N LEU B 101 ? N LEU B 101 
AA9 1 2  O MET B 43  ? O MET B 43  N LEU B 35  ? N LEU B 35  
AA9 2 3  N VAL B 34  ? N VAL B 34  O ALA B 128 ? O ALA B 128 
AA9 3 4  O TYR B 125 ? O TYR B 125 N VAL B 118 ? N VAL B 118 
AB1 1 2  N LEU B 160 ? N LEU B 160 O LEU B 249 ? O LEU B 249 
AB1 2 3  O ASN B 248 ? O ASN B 248 N VAL B 239 ? N VAL B 239 
AB1 3 4  O ILE B 232 ? O ILE B 232 N PHE B 220 ? N PHE B 220 
AB2 1 2  O MET B 308 ? O MET B 308 N ARG B 305 ? N ARG B 305 
AB2 2 3  N LEU B 304 ? N LEU B 304 O ALA B 339 ? O ALA B 339 
AB2 3 4  O ALA B 339 ? O ALA B 339 N ILE B 331 ? N ILE B 331 
AB3 1 2  N CYS B 456 ? N CYS B 456 O VAL B 464 ? O VAL B 464 
AB3 2 3  O PHE B 463 ? O PHE B 463 N ILE B 417 ? N ILE B 417 
AB3 3 4  N ASP B 420 ? N ASP B 420 O THR B 500 ? O THR B 500 
AB3 4 5  N ILE B 503 ? N ILE B 503 O GLY B 534 ? O GLY B 534 
AB4 1 2  N ILE B 490 ? N ILE B 490 O PHE B 497 ? O PHE B 497 
AB5 1 2  O LEU B 790 ? O LEU B 790 N TYR B 569 ? N TYR B 569 
AB5 2 3  N ILE B 573 ? N ILE B 573 O ILE B 781 ? O ILE B 781 
AB5 3 4  O VAL B 780 ? O VAL B 780 N VAL B 759 ? N VAL B 759 
AB5 4 5  O VAL B 760 ? O VAL B 760 N ILE B 725 ? N ILE B 725 
AB5 5 6  O LYS B 726 ? O LYS B 726 N VAL B 704 ? N VAL B 704 
AB5 6 7  O SER B 703 ? O SER B 703 N VAL B 674 ? N VAL B 674 
AB5 7 8  O THR B 673 ? O THR B 673 N VAL B 642 ? N VAL B 642 
AB5 8 9  O SER B 641 ? O SER B 641 N ALA B 585 ? N ALA B 585 
AB5 9 10 O GLY B 582 ? O GLY B 582 N GLN B 572 ? N GLN B 572 
AB6 1 2  N ASP B 591 ? N ASP B 591 O GLY B 595 ? O GLY B 595 
# 
_pdbx_entry_details.entry_id                   9BGV 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 CE1 B PHE 198 ? ? CB  B ALA 200 ? ? 1.89 
2 1 CZ  B PHE 198 ? ? CB  B ALA 200 ? ? 1.96 
3 1 NE2 B HIS 77  ? ? NB  B HEM 901 ? ? 2.00 
4 1 NE2 A GLN 142 ? ? OE1 B GLN 168 ? ? 2.16 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 TRP A 53  ? ? -94.92  -61.94  
2  1 ALA A 184 ? ? -94.03  50.56   
3  1 PRO A 196 ? ? -69.31  -172.71 
4  1 SER A 276 ? ? 60.00   71.31   
5  1 GLU A 296 ? ? 39.76   59.89   
6  1 LEU A 516 ? ? -68.00  1.50    
7  1 LEU A 565 ? ? -69.88  -177.99 
8  1 ASN A 634 ? ? -66.14  0.64    
9  1 ILE A 637 ? ? 59.64   75.79   
10 1 ASP A 705 ? ? -114.30 -159.33 
11 1 ASP A 706 ? ? -34.85  135.86  
12 1 LEU A 755 ? ? -140.60 48.23   
13 1 VAL B 167 ? ? -93.26  -62.29  
14 1 LEU B 209 ? ? -142.87 14.30   
15 1 ASP B 241 ? ? -79.05  -166.85 
16 1 ALA B 244 ? ? 65.84   -1.45   
17 1 THR B 390 ? ? 73.91   -10.13  
18 1 ALA B 409 ? ? 68.21   -4.21   
19 1 GLN B 653 ? ? -92.60  52.34   
20 1 PHE B 711 ? ? 67.34   -4.70   
21 1 VAL B 718 ? ? 43.04   27.92   
22 1 PRO B 721 ? ? -69.08  74.23   
23 1 GLU B 765 ? ? -130.44 -37.08  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BGV 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BGV 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.65 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               353471 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Dimer of DosP' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BGV 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'Quantifoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BGV 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BGV 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ARG 2   ? A ARG 2   
3  1 Y 1 A GLN 3   ? A GLN 3   
4  1 Y 1 A ASP 4   ? A ASP 4   
5  1 Y 1 A ALA 5   ? A ALA 5   
6  1 Y 1 A GLU 6   ? A GLU 6   
7  1 Y 1 A VAL 7   ? A VAL 7   
8  1 Y 1 A ILE 8   ? A ILE 8   
9  1 Y 1 A MET 9   ? A MET 9   
10 1 Y 1 A LYS 10  ? A LYS 10  
11 1 Y 1 A LEU 11  ? A LEU 11  
12 1 Y 1 A THR 12  ? A THR 12  
13 1 Y 1 A ASP 13  ? A ASP 13  
14 1 Y 1 A ALA 14  ? A ALA 14  
15 1 Y 1 A ASP 15  ? A ASP 15  
16 1 Y 1 A SER 16  ? A SER 16  
17 1 Y 1 A ALA 17  ? A ALA 17  
18 1 Y 1 A ALA 18  ? A ALA 18  
19 1 Y 1 A ASP 19  ? A ASP 19  
20 1 Y 1 A ILE 807 ? A ILE 807 
21 1 Y 1 B MET 1   ? B MET 1   
22 1 Y 1 B ARG 2   ? B ARG 2   
23 1 Y 1 B GLN 3   ? B GLN 3   
24 1 Y 1 B ASP 4   ? B ASP 4   
25 1 Y 1 B ALA 5   ? B ALA 5   
26 1 Y 1 B GLU 6   ? B GLU 6   
27 1 Y 1 B VAL 7   ? B VAL 7   
28 1 Y 1 B ILE 8   ? B ILE 8   
29 1 Y 1 B MET 9   ? B MET 9   
30 1 Y 1 B LYS 10  ? B LYS 10  
31 1 Y 1 B LEU 11  ? B LEU 11  
32 1 Y 1 B THR 12  ? B THR 12  
33 1 Y 1 B ASP 13  ? B ASP 13  
34 1 Y 1 B ALA 14  ? B ALA 14  
35 1 Y 1 B ASP 15  ? B ASP 15  
36 1 Y 1 B SER 16  ? B SER 16  
37 1 Y 1 B ALA 17  ? B ALA 17  
38 1 Y 1 B ALA 18  ? B ALA 18  
39 1 Y 1 B ASP 19  ? B ASP 19  
40 1 Y 1 B ILE 807 ? B ILE 807 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CYS N    N  N N 74  
CYS CA   C  N R 75  
CYS C    C  N N 76  
CYS O    O  N N 77  
CYS CB   C  N N 78  
CYS SG   S  N N 79  
CYS OXT  O  N N 80  
CYS H    H  N N 81  
CYS H2   H  N N 82  
CYS HA   H  N N 83  
CYS HB2  H  N N 84  
CYS HB3  H  N N 85  
CYS HG   H  N N 86  
CYS HXT  H  N N 87  
GLN N    N  N N 88  
GLN CA   C  N S 89  
GLN C    C  N N 90  
GLN O    O  N N 91  
GLN CB   C  N N 92  
GLN CG   C  N N 93  
GLN CD   C  N N 94  
GLN OE1  O  N N 95  
GLN NE2  N  N N 96  
GLN OXT  O  N N 97  
GLN H    H  N N 98  
GLN H2   H  N N 99  
GLN HA   H  N N 100 
GLN HB2  H  N N 101 
GLN HB3  H  N N 102 
GLN HG2  H  N N 103 
GLN HG3  H  N N 104 
GLN HE21 H  N N 105 
GLN HE22 H  N N 106 
GLN HXT  H  N N 107 
GLU N    N  N N 108 
GLU CA   C  N S 109 
GLU C    C  N N 110 
GLU O    O  N N 111 
GLU CB   C  N N 112 
GLU CG   C  N N 113 
GLU CD   C  N N 114 
GLU OE1  O  N N 115 
GLU OE2  O  N N 116 
GLU OXT  O  N N 117 
GLU H    H  N N 118 
GLU H2   H  N N 119 
GLU HA   H  N N 120 
GLU HB2  H  N N 121 
GLU HB3  H  N N 122 
GLU HG2  H  N N 123 
GLU HG3  H  N N 124 
GLU HE2  H  N N 125 
GLU HXT  H  N N 126 
GLY N    N  N N 127 
GLY CA   C  N N 128 
GLY C    C  N N 129 
GLY O    O  N N 130 
GLY OXT  O  N N 131 
GLY H    H  N N 132 
GLY H2   H  N N 133 
GLY HA2  H  N N 134 
GLY HA3  H  N N 135 
GLY HXT  H  N N 136 
HEM CHA  C  N N 137 
HEM CHB  C  N N 138 
HEM CHC  C  N N 139 
HEM CHD  C  N N 140 
HEM C1A  C  Y N 141 
HEM C2A  C  Y N 142 
HEM C3A  C  Y N 143 
HEM C4A  C  Y N 144 
HEM CMA  C  N N 145 
HEM CAA  C  N N 146 
HEM CBA  C  N N 147 
HEM CGA  C  N N 148 
HEM O1A  O  N N 149 
HEM O2A  O  N N 150 
HEM C1B  C  N N 151 
HEM C2B  C  N N 152 
HEM C3B  C  N N 153 
HEM C4B  C  N N 154 
HEM CMB  C  N N 155 
HEM CAB  C  N N 156 
HEM CBB  C  N N 157 
HEM C1C  C  Y N 158 
HEM C2C  C  Y N 159 
HEM C3C  C  Y N 160 
HEM C4C  C  Y N 161 
HEM CMC  C  N N 162 
HEM CAC  C  N N 163 
HEM CBC  C  N N 164 
HEM C1D  C  N N 165 
HEM C2D  C  N N 166 
HEM C3D  C  N N 167 
HEM C4D  C  N N 168 
HEM CMD  C  N N 169 
HEM CAD  C  N N 170 
HEM CBD  C  N N 171 
HEM CGD  C  N N 172 
HEM O1D  O  N N 173 
HEM O2D  O  N N 174 
HEM NA   N  Y N 175 
HEM NB   N  N N 176 
HEM NC   N  Y N 177 
HEM ND   N  N N 178 
HEM FE   FE N N 179 
HEM HHB  H  N N 180 
HEM HHC  H  N N 181 
HEM HHD  H  N N 182 
HEM HMA  H  N N 183 
HEM HMAA H  N N 184 
HEM HMAB H  N N 185 
HEM HAA  H  N N 186 
HEM HAAA H  N N 187 
HEM HBA  H  N N 188 
HEM HBAA H  N N 189 
HEM HMB  H  N N 190 
HEM HMBA H  N N 191 
HEM HMBB H  N N 192 
HEM HAB  H  N N 193 
HEM HBB  H  N N 194 
HEM HBBA H  N N 195 
HEM HMC  H  N N 196 
HEM HMCA H  N N 197 
HEM HMCB H  N N 198 
HEM HAC  H  N N 199 
HEM HBC  H  N N 200 
HEM HBCA H  N N 201 
HEM HMD  H  N N 202 
HEM HMDA H  N N 203 
HEM HMDB H  N N 204 
HEM HAD  H  N N 205 
HEM HADA H  N N 206 
HEM HBD  H  N N 207 
HEM HBDA H  N N 208 
HEM H2A  H  N N 209 
HEM H2D  H  N N 210 
HEM HHA  H  N N 211 
HIS N    N  N N 212 
HIS CA   C  N S 213 
HIS C    C  N N 214 
HIS O    O  N N 215 
HIS CB   C  N N 216 
HIS CG   C  Y N 217 
HIS ND1  N  Y N 218 
HIS CD2  C  Y N 219 
HIS CE1  C  Y N 220 
HIS NE2  N  Y N 221 
HIS OXT  O  N N 222 
HIS H    H  N N 223 
HIS H2   H  N N 224 
HIS HA   H  N N 225 
HIS HB2  H  N N 226 
HIS HB3  H  N N 227 
HIS HD1  H  N N 228 
HIS HD2  H  N N 229 
HIS HE1  H  N N 230 
HIS HE2  H  N N 231 
HIS HXT  H  N N 232 
ILE N    N  N N 233 
ILE CA   C  N S 234 
ILE C    C  N N 235 
ILE O    O  N N 236 
ILE CB   C  N S 237 
ILE CG1  C  N N 238 
ILE CG2  C  N N 239 
ILE CD1  C  N N 240 
ILE OXT  O  N N 241 
ILE H    H  N N 242 
ILE H2   H  N N 243 
ILE HA   H  N N 244 
ILE HB   H  N N 245 
ILE HG12 H  N N 246 
ILE HG13 H  N N 247 
ILE HG21 H  N N 248 
ILE HG22 H  N N 249 
ILE HG23 H  N N 250 
ILE HD11 H  N N 251 
ILE HD12 H  N N 252 
ILE HD13 H  N N 253 
ILE HXT  H  N N 254 
LEU N    N  N N 255 
LEU CA   C  N S 256 
LEU C    C  N N 257 
LEU O    O  N N 258 
LEU CB   C  N N 259 
LEU CG   C  N N 260 
LEU CD1  C  N N 261 
LEU CD2  C  N N 262 
LEU OXT  O  N N 263 
LEU H    H  N N 264 
LEU H2   H  N N 265 
LEU HA   H  N N 266 
LEU HB2  H  N N 267 
LEU HB3  H  N N 268 
LEU HG   H  N N 269 
LEU HD11 H  N N 270 
LEU HD12 H  N N 271 
LEU HD13 H  N N 272 
LEU HD21 H  N N 273 
LEU HD22 H  N N 274 
LEU HD23 H  N N 275 
LEU HXT  H  N N 276 
LYS N    N  N N 277 
LYS CA   C  N S 278 
LYS C    C  N N 279 
LYS O    O  N N 280 
LYS CB   C  N N 281 
LYS CG   C  N N 282 
LYS CD   C  N N 283 
LYS CE   C  N N 284 
LYS NZ   N  N N 285 
LYS OXT  O  N N 286 
LYS H    H  N N 287 
LYS H2   H  N N 288 
LYS HA   H  N N 289 
LYS HB2  H  N N 290 
LYS HB3  H  N N 291 
LYS HG2  H  N N 292 
LYS HG3  H  N N 293 
LYS HD2  H  N N 294 
LYS HD3  H  N N 295 
LYS HE2  H  N N 296 
LYS HE3  H  N N 297 
LYS HZ1  H  N N 298 
LYS HZ2  H  N N 299 
LYS HZ3  H  N N 300 
LYS HXT  H  N N 301 
MET N    N  N N 302 
MET CA   C  N S 303 
MET C    C  N N 304 
MET O    O  N N 305 
MET CB   C  N N 306 
MET CG   C  N N 307 
MET SD   S  N N 308 
MET CE   C  N N 309 
MET OXT  O  N N 310 
MET H    H  N N 311 
MET H2   H  N N 312 
MET HA   H  N N 313 
MET HB2  H  N N 314 
MET HB3  H  N N 315 
MET HG2  H  N N 316 
MET HG3  H  N N 317 
MET HE1  H  N N 318 
MET HE2  H  N N 319 
MET HE3  H  N N 320 
MET HXT  H  N N 321 
PHE N    N  N N 322 
PHE CA   C  N S 323 
PHE C    C  N N 324 
PHE O    O  N N 325 
PHE CB   C  N N 326 
PHE CG   C  Y N 327 
PHE CD1  C  Y N 328 
PHE CD2  C  Y N 329 
PHE CE1  C  Y N 330 
PHE CE2  C  Y N 331 
PHE CZ   C  Y N 332 
PHE OXT  O  N N 333 
PHE H    H  N N 334 
PHE H2   H  N N 335 
PHE HA   H  N N 336 
PHE HB2  H  N N 337 
PHE HB3  H  N N 338 
PHE HD1  H  N N 339 
PHE HD2  H  N N 340 
PHE HE1  H  N N 341 
PHE HE2  H  N N 342 
PHE HZ   H  N N 343 
PHE HXT  H  N N 344 
PRO N    N  N N 345 
PRO CA   C  N S 346 
PRO C    C  N N 347 
PRO O    O  N N 348 
PRO CB   C  N N 349 
PRO CG   C  N N 350 
PRO CD   C  N N 351 
PRO OXT  O  N N 352 
PRO H    H  N N 353 
PRO HA   H  N N 354 
PRO HB2  H  N N 355 
PRO HB3  H  N N 356 
PRO HG2  H  N N 357 
PRO HG3  H  N N 358 
PRO HD2  H  N N 359 
PRO HD3  H  N N 360 
PRO HXT  H  N N 361 
SER N    N  N N 362 
SER CA   C  N S 363 
SER C    C  N N 364 
SER O    O  N N 365 
SER CB   C  N N 366 
SER OG   O  N N 367 
SER OXT  O  N N 368 
SER H    H  N N 369 
SER H2   H  N N 370 
SER HA   H  N N 371 
SER HB2  H  N N 372 
SER HB3  H  N N 373 
SER HG   H  N N 374 
SER HXT  H  N N 375 
THR N    N  N N 376 
THR CA   C  N S 377 
THR C    C  N N 378 
THR O    O  N N 379 
THR CB   C  N R 380 
THR OG1  O  N N 381 
THR CG2  C  N N 382 
THR OXT  O  N N 383 
THR H    H  N N 384 
THR H2   H  N N 385 
THR HA   H  N N 386 
THR HB   H  N N 387 
THR HG1  H  N N 388 
THR HG21 H  N N 389 
THR HG22 H  N N 390 
THR HG23 H  N N 391 
THR HXT  H  N N 392 
TRP N    N  N N 393 
TRP CA   C  N S 394 
TRP C    C  N N 395 
TRP O    O  N N 396 
TRP CB   C  N N 397 
TRP CG   C  Y N 398 
TRP CD1  C  Y N 399 
TRP CD2  C  Y N 400 
TRP NE1  N  Y N 401 
TRP CE2  C  Y N 402 
TRP CE3  C  Y N 403 
TRP CZ2  C  Y N 404 
TRP CZ3  C  Y N 405 
TRP CH2  C  Y N 406 
TRP OXT  O  N N 407 
TRP H    H  N N 408 
TRP H2   H  N N 409 
TRP HA   H  N N 410 
TRP HB2  H  N N 411 
TRP HB3  H  N N 412 
TRP HD1  H  N N 413 
TRP HE1  H  N N 414 
TRP HE3  H  N N 415 
TRP HZ2  H  N N 416 
TRP HZ3  H  N N 417 
TRP HH2  H  N N 418 
TRP HXT  H  N N 419 
TYR N    N  N N 420 
TYR CA   C  N S 421 
TYR C    C  N N 422 
TYR O    O  N N 423 
TYR CB   C  N N 424 
TYR CG   C  Y N 425 
TYR CD1  C  Y N 426 
TYR CD2  C  Y N 427 
TYR CE1  C  Y N 428 
TYR CE2  C  Y N 429 
TYR CZ   C  Y N 430 
TYR OH   O  N N 431 
TYR OXT  O  N N 432 
TYR H    H  N N 433 
TYR H2   H  N N 434 
TYR HA   H  N N 435 
TYR HB2  H  N N 436 
TYR HB3  H  N N 437 
TYR HD1  H  N N 438 
TYR HD2  H  N N 439 
TYR HE1  H  N N 440 
TYR HE2  H  N N 441 
TYR HH   H  N N 442 
TYR HXT  H  N N 443 
VAL N    N  N N 444 
VAL CA   C  N S 445 
VAL C    C  N N 446 
VAL O    O  N N 447 
VAL CB   C  N N 448 
VAL CG1  C  N N 449 
VAL CG2  C  N N 450 
VAL OXT  O  N N 451 
VAL H    H  N N 452 
VAL H2   H  N N 453 
VAL HA   H  N N 454 
VAL HB   H  N N 455 
VAL HG11 H  N N 456 
VAL HG12 H  N N 457 
VAL HG13 H  N N 458 
VAL HG21 H  N N 459 
VAL HG22 H  N N 460 
VAL HG23 H  N N 461 
VAL HXT  H  N N 462 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HEM CHA C1A  sing N N 129 
HEM CHA C4D  doub N N 130 
HEM CHA HHA  sing N N 131 
HEM CHB C4A  sing N N 132 
HEM CHB C1B  doub N N 133 
HEM CHB HHB  sing N N 134 
HEM CHC C4B  sing N N 135 
HEM CHC C1C  doub N N 136 
HEM CHC HHC  sing N N 137 
HEM CHD C4C  doub N N 138 
HEM CHD C1D  sing N N 139 
HEM CHD HHD  sing N N 140 
HEM C1A C2A  doub Y N 141 
HEM C1A NA   sing Y N 142 
HEM C2A C3A  sing Y N 143 
HEM C2A CAA  sing N N 144 
HEM C3A C4A  doub Y N 145 
HEM C3A CMA  sing N N 146 
HEM C4A NA   sing Y N 147 
HEM CMA HMA  sing N N 148 
HEM CMA HMAA sing N N 149 
HEM CMA HMAB sing N N 150 
HEM CAA CBA  sing N N 151 
HEM CAA HAA  sing N N 152 
HEM CAA HAAA sing N N 153 
HEM CBA CGA  sing N N 154 
HEM CBA HBA  sing N N 155 
HEM CBA HBAA sing N N 156 
HEM CGA O1A  doub N N 157 
HEM CGA O2A  sing N N 158 
HEM C1B C2B  sing N N 159 
HEM C1B NB   sing N N 160 
HEM C2B C3B  doub N N 161 
HEM C2B CMB  sing N N 162 
HEM C3B C4B  sing N N 163 
HEM C3B CAB  sing N N 164 
HEM C4B NB   doub N N 165 
HEM CMB HMB  sing N N 166 
HEM CMB HMBA sing N N 167 
HEM CMB HMBB sing N N 168 
HEM CAB CBB  doub N N 169 
HEM CAB HAB  sing N N 170 
HEM CBB HBB  sing N N 171 
HEM CBB HBBA sing N N 172 
HEM C1C C2C  sing Y N 173 
HEM C1C NC   sing Y N 174 
HEM C2C C3C  doub Y N 175 
HEM C2C CMC  sing N N 176 
HEM C3C C4C  sing Y N 177 
HEM C3C CAC  sing N N 178 
HEM C4C NC   sing Y N 179 
HEM CMC HMC  sing N N 180 
HEM CMC HMCA sing N N 181 
HEM CMC HMCB sing N N 182 
HEM CAC CBC  doub N N 183 
HEM CAC HAC  sing N N 184 
HEM CBC HBC  sing N N 185 
HEM CBC HBCA sing N N 186 
HEM C1D C2D  sing N N 187 
HEM C1D ND   doub N N 188 
HEM C2D C3D  doub N N 189 
HEM C2D CMD  sing N N 190 
HEM C3D C4D  sing N N 191 
HEM C3D CAD  sing N N 192 
HEM C4D ND   sing N N 193 
HEM CMD HMD  sing N N 194 
HEM CMD HMDA sing N N 195 
HEM CMD HMDB sing N N 196 
HEM CAD CBD  sing N N 197 
HEM CAD HAD  sing N N 198 
HEM CAD HADA sing N N 199 
HEM CBD CGD  sing N N 200 
HEM CBD HBD  sing N N 201 
HEM CBD HBDA sing N N 202 
HEM CGD O1D  doub N N 203 
HEM CGD O2D  sing N N 204 
HEM O2A H2A  sing N N 205 
HEM O2D H2D  sing N N 206 
HEM FE  NA   sing N N 207 
HEM FE  NB   sing N N 208 
HEM FE  NC   sing N N 209 
HEM FE  ND   sing N N 210 
HIS N   CA   sing N N 211 
HIS N   H    sing N N 212 
HIS N   H2   sing N N 213 
HIS CA  C    sing N N 214 
HIS CA  CB   sing N N 215 
HIS CA  HA   sing N N 216 
HIS C   O    doub N N 217 
HIS C   OXT  sing N N 218 
HIS CB  CG   sing N N 219 
HIS CB  HB2  sing N N 220 
HIS CB  HB3  sing N N 221 
HIS CG  ND1  sing Y N 222 
HIS CG  CD2  doub Y N 223 
HIS ND1 CE1  doub Y N 224 
HIS ND1 HD1  sing N N 225 
HIS CD2 NE2  sing Y N 226 
HIS CD2 HD2  sing N N 227 
HIS CE1 NE2  sing Y N 228 
HIS CE1 HE1  sing N N 229 
HIS NE2 HE2  sing N N 230 
HIS OXT HXT  sing N N 231 
ILE N   CA   sing N N 232 
ILE N   H    sing N N 233 
ILE N   H2   sing N N 234 
ILE CA  C    sing N N 235 
ILE CA  CB   sing N N 236 
ILE CA  HA   sing N N 237 
ILE C   O    doub N N 238 
ILE C   OXT  sing N N 239 
ILE CB  CG1  sing N N 240 
ILE CB  CG2  sing N N 241 
ILE CB  HB   sing N N 242 
ILE CG1 CD1  sing N N 243 
ILE CG1 HG12 sing N N 244 
ILE CG1 HG13 sing N N 245 
ILE CG2 HG21 sing N N 246 
ILE CG2 HG22 sing N N 247 
ILE CG2 HG23 sing N N 248 
ILE CD1 HD11 sing N N 249 
ILE CD1 HD12 sing N N 250 
ILE CD1 HD13 sing N N 251 
ILE OXT HXT  sing N N 252 
LEU N   CA   sing N N 253 
LEU N   H    sing N N 254 
LEU N   H2   sing N N 255 
LEU CA  C    sing N N 256 
LEU CA  CB   sing N N 257 
LEU CA  HA   sing N N 258 
LEU C   O    doub N N 259 
LEU C   OXT  sing N N 260 
LEU CB  CG   sing N N 261 
LEU CB  HB2  sing N N 262 
LEU CB  HB3  sing N N 263 
LEU CG  CD1  sing N N 264 
LEU CG  CD2  sing N N 265 
LEU CG  HG   sing N N 266 
LEU CD1 HD11 sing N N 267 
LEU CD1 HD12 sing N N 268 
LEU CD1 HD13 sing N N 269 
LEU CD2 HD21 sing N N 270 
LEU CD2 HD22 sing N N 271 
LEU CD2 HD23 sing N N 272 
LEU OXT HXT  sing N N 273 
LYS N   CA   sing N N 274 
LYS N   H    sing N N 275 
LYS N   H2   sing N N 276 
LYS CA  C    sing N N 277 
LYS CA  CB   sing N N 278 
LYS CA  HA   sing N N 279 
LYS C   O    doub N N 280 
LYS C   OXT  sing N N 281 
LYS CB  CG   sing N N 282 
LYS CB  HB2  sing N N 283 
LYS CB  HB3  sing N N 284 
LYS CG  CD   sing N N 285 
LYS CG  HG2  sing N N 286 
LYS CG  HG3  sing N N 287 
LYS CD  CE   sing N N 288 
LYS CD  HD2  sing N N 289 
LYS CD  HD3  sing N N 290 
LYS CE  NZ   sing N N 291 
LYS CE  HE2  sing N N 292 
LYS CE  HE3  sing N N 293 
LYS NZ  HZ1  sing N N 294 
LYS NZ  HZ2  sing N N 295 
LYS NZ  HZ3  sing N N 296 
LYS OXT HXT  sing N N 297 
MET N   CA   sing N N 298 
MET N   H    sing N N 299 
MET N   H2   sing N N 300 
MET CA  C    sing N N 301 
MET CA  CB   sing N N 302 
MET CA  HA   sing N N 303 
MET C   O    doub N N 304 
MET C   OXT  sing N N 305 
MET CB  CG   sing N N 306 
MET CB  HB2  sing N N 307 
MET CB  HB3  sing N N 308 
MET CG  SD   sing N N 309 
MET CG  HG2  sing N N 310 
MET CG  HG3  sing N N 311 
MET SD  CE   sing N N 312 
MET CE  HE1  sing N N 313 
MET CE  HE2  sing N N 314 
MET CE  HE3  sing N N 315 
MET OXT HXT  sing N N 316 
PHE N   CA   sing N N 317 
PHE N   H    sing N N 318 
PHE N   H2   sing N N 319 
PHE CA  C    sing N N 320 
PHE CA  CB   sing N N 321 
PHE CA  HA   sing N N 322 
PHE C   O    doub N N 323 
PHE C   OXT  sing N N 324 
PHE CB  CG   sing N N 325 
PHE CB  HB2  sing N N 326 
PHE CB  HB3  sing N N 327 
PHE CG  CD1  doub Y N 328 
PHE CG  CD2  sing Y N 329 
PHE CD1 CE1  sing Y N 330 
PHE CD1 HD1  sing N N 331 
PHE CD2 CE2  doub Y N 332 
PHE CD2 HD2  sing N N 333 
PHE CE1 CZ   doub Y N 334 
PHE CE1 HE1  sing N N 335 
PHE CE2 CZ   sing Y N 336 
PHE CE2 HE2  sing N N 337 
PHE CZ  HZ   sing N N 338 
PHE OXT HXT  sing N N 339 
PRO N   CA   sing N N 340 
PRO N   CD   sing N N 341 
PRO N   H    sing N N 342 
PRO CA  C    sing N N 343 
PRO CA  CB   sing N N 344 
PRO CA  HA   sing N N 345 
PRO C   O    doub N N 346 
PRO C   OXT  sing N N 347 
PRO CB  CG   sing N N 348 
PRO CB  HB2  sing N N 349 
PRO CB  HB3  sing N N 350 
PRO CG  CD   sing N N 351 
PRO CG  HG2  sing N N 352 
PRO CG  HG3  sing N N 353 
PRO CD  HD2  sing N N 354 
PRO CD  HD3  sing N N 355 
PRO OXT HXT  sing N N 356 
SER N   CA   sing N N 357 
SER N   H    sing N N 358 
SER N   H2   sing N N 359 
SER CA  C    sing N N 360 
SER CA  CB   sing N N 361 
SER CA  HA   sing N N 362 
SER C   O    doub N N 363 
SER C   OXT  sing N N 364 
SER CB  OG   sing N N 365 
SER CB  HB2  sing N N 366 
SER CB  HB3  sing N N 367 
SER OG  HG   sing N N 368 
SER OXT HXT  sing N N 369 
THR N   CA   sing N N 370 
THR N   H    sing N N 371 
THR N   H2   sing N N 372 
THR CA  C    sing N N 373 
THR CA  CB   sing N N 374 
THR CA  HA   sing N N 375 
THR C   O    doub N N 376 
THR C   OXT  sing N N 377 
THR CB  OG1  sing N N 378 
THR CB  CG2  sing N N 379 
THR CB  HB   sing N N 380 
THR OG1 HG1  sing N N 381 
THR CG2 HG21 sing N N 382 
THR CG2 HG22 sing N N 383 
THR CG2 HG23 sing N N 384 
THR OXT HXT  sing N N 385 
TRP N   CA   sing N N 386 
TRP N   H    sing N N 387 
TRP N   H2   sing N N 388 
TRP CA  C    sing N N 389 
TRP CA  CB   sing N N 390 
TRP CA  HA   sing N N 391 
TRP C   O    doub N N 392 
TRP C   OXT  sing N N 393 
TRP CB  CG   sing N N 394 
TRP CB  HB2  sing N N 395 
TRP CB  HB3  sing N N 396 
TRP CG  CD1  doub Y N 397 
TRP CG  CD2  sing Y N 398 
TRP CD1 NE1  sing Y N 399 
TRP CD1 HD1  sing N N 400 
TRP CD2 CE2  doub Y N 401 
TRP CD2 CE3  sing Y N 402 
TRP NE1 CE2  sing Y N 403 
TRP NE1 HE1  sing N N 404 
TRP CE2 CZ2  sing Y N 405 
TRP CE3 CZ3  doub Y N 406 
TRP CE3 HE3  sing N N 407 
TRP CZ2 CH2  doub Y N 408 
TRP CZ2 HZ2  sing N N 409 
TRP CZ3 CH2  sing Y N 410 
TRP CZ3 HZ3  sing N N 411 
TRP CH2 HH2  sing N N 412 
TRP OXT HXT  sing N N 413 
TYR N   CA   sing N N 414 
TYR N   H    sing N N 415 
TYR N   H2   sing N N 416 
TYR CA  C    sing N N 417 
TYR CA  CB   sing N N 418 
TYR CA  HA   sing N N 419 
TYR C   O    doub N N 420 
TYR C   OXT  sing N N 421 
TYR CB  CG   sing N N 422 
TYR CB  HB2  sing N N 423 
TYR CB  HB3  sing N N 424 
TYR CG  CD1  doub Y N 425 
TYR CG  CD2  sing Y N 426 
TYR CD1 CE1  sing Y N 427 
TYR CD1 HD1  sing N N 428 
TYR CD2 CE2  doub Y N 429 
TYR CD2 HD2  sing N N 430 
TYR CE1 CZ   doub Y N 431 
TYR CE1 HE1  sing N N 432 
TYR CE2 CZ   sing Y N 433 
TYR CE2 HE2  sing N N 434 
TYR CZ  OH   sing N N 435 
TYR OH  HH   sing N N 436 
TYR OXT HXT  sing N N 437 
VAL N   CA   sing N N 438 
VAL N   H    sing N N 439 
VAL N   H2   sing N N 440 
VAL CA  C    sing N N 441 
VAL CA  CB   sing N N 442 
VAL CA  HA   sing N N 443 
VAL C   O    doub N N 444 
VAL C   OXT  sing N N 445 
VAL CB  CG1  sing N N 446 
VAL CB  CG2  sing N N 447 
VAL CB  HB   sing N N 448 
VAL CG1 HG11 sing N N 449 
VAL CG1 HG12 sing N N 450 
VAL CG1 HG13 sing N N 451 
VAL CG2 HG21 sing N N 452 
VAL CG2 HG22 sing N N 453 
VAL CG2 HG23 sing N N 454 
VAL OXT HXT  sing N N 455 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-19 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BGV 
_em_admin.last_update        2024-11-27 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'DosP R97A straight form' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                MEGADALTONS 
_em_entity_assembly_molwt.value                0.2 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             E.coli 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             E.coli 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?         ?   
MASKING                         ? 3  ? ? ? ?         ?   
'CTF CORRECTION'                ? 4  1 ? ? ?         ?   
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?   
'MODEL FITTING'                 ? 7  ? ? ? ?         ?   
'MODEL REFINEMENT'              ? 8  ? ? ? ?         ?   
OTHER                           ? 9  ? ? ? ?         ?   
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? cryoSPARC 4.2 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? cryoSPARC 4.2 
CLASSIFICATION                  ? 12 1 ? ? ?         ?   
RECONSTRUCTION                  ? 13 1 ? ? ?         ?   
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?   
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?   
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?   
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?   
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?   
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R00GM141261 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' U24GM129547 2 
# 
_atom_sites.entry_id                    9BGV 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
FE 
H  
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1     N  N   . GLY A 1 20  ? 233.557 219.634 327.640 1.00 158.34 ? 20  GLY A N   1 
ATOM   2     C  CA  . GLY A 1 20  ? 233.465 219.251 326.243 1.00 158.34 ? 20  GLY A CA  1 
ATOM   3     C  C   . GLY A 1 20  ? 233.234 220.428 325.316 1.00 158.34 ? 20  GLY A C   1 
ATOM   4     O  O   . GLY A 1 20  ? 232.391 221.285 325.584 1.00 158.34 ? 20  GLY A O   1 
ATOM   5     N  N   . ILE A 1 21  ? 233.995 220.468 324.217 1.00 153.64 ? 21  ILE A N   1 
ATOM   6     C  CA  . ILE A 1 21  ? 233.902 221.569 323.262 1.00 153.64 ? 21  ILE A CA  1 
ATOM   7     C  C   . ILE A 1 21  ? 233.454 221.114 321.879 1.00 153.64 ? 21  ILE A C   1 
ATOM   8     O  O   . ILE A 1 21  ? 233.131 221.960 321.032 1.00 153.64 ? 21  ILE A O   1 
ATOM   9     C  CB  . ILE A 1 21  ? 235.253 222.307 323.170 1.00 153.64 ? 21  ILE A CB  1 
ATOM   10    C  CG1 . ILE A 1 21  ? 235.051 223.758 322.726 1.00 153.64 ? 21  ILE A CG1 1 
ATOM   11    C  CG2 . ILE A 1 21  ? 236.198 221.580 322.229 1.00 153.64 ? 21  ILE A CG2 1 
ATOM   12    C  CD1 . ILE A 1 21  ? 234.155 224.561 323.644 1.00 153.64 ? 21  ILE A CD1 1 
ATOM   13    N  N   . PHE A 1 22  ? 233.411 219.808 321.623 1.00 153.57 ? 22  PHE A N   1 
ATOM   14    C  CA  . PHE A 1 22  ? 233.004 219.330 320.307 1.00 153.57 ? 22  PHE A CA  1 
ATOM   15    C  C   . PHE A 1 22  ? 231.490 219.422 320.135 1.00 153.57 ? 22  PHE A C   1 
ATOM   16    O  O   . PHE A 1 22  ? 231.002 219.798 319.064 1.00 153.57 ? 22  PHE A O   1 
ATOM   17    C  CB  . PHE A 1 22  ? 233.510 217.904 320.098 1.00 153.57 ? 22  PHE A CB  1 
ATOM   18    C  CG  . PHE A 1 22  ? 235.015 217.793 320.091 1.00 153.57 ? 22  PHE A CG  1 
ATOM   19    C  CD1 . PHE A 1 22  ? 235.813 218.920 319.960 1.00 153.57 ? 22  PHE A CD1 1 
ATOM   20    C  CD2 . PHE A 1 22  ? 235.630 216.563 320.241 1.00 153.57 ? 22  PHE A CD2 1 
ATOM   21    C  CE1 . PHE A 1 22  ? 237.191 218.818 319.969 1.00 153.57 ? 22  PHE A CE1 1 
ATOM   22    C  CE2 . PHE A 1 22  ? 237.006 216.455 320.250 1.00 153.57 ? 22  PHE A CE2 1 
ATOM   23    C  CZ  . PHE A 1 22  ? 237.788 217.582 320.114 1.00 153.57 ? 22  PHE A CZ  1 
ATOM   24    N  N   . PHE A 1 23  ? 230.733 219.099 321.188 1.00 151.07 ? 23  PHE A N   1 
ATOM   25    C  CA  . PHE A 1 23  ? 229.311 219.439 321.195 1.00 151.07 ? 23  PHE A CA  1 
ATOM   26    C  C   . PHE A 1 23  ? 229.063 220.922 320.948 1.00 151.07 ? 23  PHE A C   1 
ATOM   27    O  O   . PHE A 1 23  ? 228.305 221.246 320.017 1.00 151.07 ? 23  PHE A O   1 
ATOM   28    C  CB  . PHE A 1 23  ? 228.668 218.987 322.515 1.00 151.07 ? 23  PHE A CB  1 
ATOM   29    C  CG  . PHE A 1 23  ? 227.244 219.454 322.692 1.00 151.07 ? 23  PHE A CG  1 
ATOM   30    C  CD1 . PHE A 1 23  ? 226.191 218.827 322.050 1.00 151.07 ? 23  PHE A CD1 1 
ATOM   31    C  CD2 . PHE A 1 23  ? 226.968 220.558 323.483 1.00 151.07 ? 23  PHE A CD2 1 
ATOM   32    C  CE1 . PHE A 1 23  ? 224.892 219.274 322.215 1.00 151.07 ? 23  PHE A CE1 1 
ATOM   33    C  CE2 . PHE A 1 23  ? 225.675 221.015 323.649 1.00 151.07 ? 23  PHE A CE2 1 
ATOM   34    C  CZ  . PHE A 1 23  ? 224.634 220.372 323.013 1.00 151.07 ? 23  PHE A CZ  1 
ATOM   35    N  N   . PRO A 1 24  ? 229.655 221.862 321.699 1.00 153.73 ? 24  PRO A N   1 
ATOM   36    C  CA  . PRO A 1 24  ? 229.438 223.281 321.370 1.00 153.73 ? 24  PRO A CA  1 
ATOM   37    C  C   . PRO A 1 24  ? 229.957 223.666 320.000 1.00 153.73 ? 24  PRO A C   1 
ATOM   38    O  O   . PRO A 1 24  ? 229.452 224.624 319.402 1.00 153.73 ? 24  PRO A O   1 
ATOM   39    C  CB  . PRO A 1 24  ? 230.191 224.022 322.484 1.00 153.73 ? 24  PRO A CB  1 
ATOM   40    C  CG  . PRO A 1 24  ? 230.275 223.054 323.597 1.00 153.73 ? 24  PRO A CG  1 
ATOM   41    C  CD  . PRO A 1 24  ? 230.431 221.720 322.945 1.00 153.73 ? 24  PRO A CD  1 
ATOM   42    N  N   . ALA A 1 25  ? 230.975 222.968 319.495 1.00 149.12 ? 25  ALA A N   1 
ATOM   43    C  CA  . ALA A 1 25  ? 231.460 223.253 318.151 1.00 149.12 ? 25  ALA A CA  1 
ATOM   44    C  C   . ALA A 1 25  ? 230.415 222.883 317.109 1.00 149.12 ? 25  ALA A C   1 
ATOM   45    O  O   . ALA A 1 25  ? 230.047 223.704 316.262 1.00 149.12 ? 25  ALA A O   1 
ATOM   46    C  CB  . ALA A 1 25  ? 232.766 222.503 317.898 1.00 149.12 ? 25  ALA A CB  1 
ATOM   47    N  N   . LEU A 1 26  ? 229.902 221.655 317.179 1.00 145.33 ? 26  LEU A N   1 
ATOM   48    C  CA  . LEU A 1 26  ? 228.891 221.215 316.231 1.00 145.33 ? 26  LEU A CA  1 
ATOM   49    C  C   . LEU A 1 26  ? 227.539 221.863 316.479 1.00 145.33 ? 26  LEU A C   1 
ATOM   50    O  O   . LEU A 1 26  ? 226.641 221.716 315.645 1.00 145.33 ? 26  LEU A O   1 
ATOM   51    C  CB  . LEU A 1 26  ? 228.764 219.692 316.270 1.00 145.33 ? 26  LEU A CB  1 
ATOM   52    C  CG  . LEU A 1 26  ? 229.981 218.925 315.746 1.00 145.33 ? 26  LEU A CG  1 
ATOM   53    C  CD1 . LEU A 1 26  ? 229.758 217.426 315.830 1.00 145.33 ? 26  LEU A CD1 1 
ATOM   54    C  CD2 . LEU A 1 26  ? 230.303 219.339 314.318 1.00 145.33 ? 26  LEU A CD2 1 
ATOM   55    N  N   . GLU A 1 27  ? 227.372 222.565 317.603 1.00 146.87 ? 27  GLU A N   1 
ATOM   56    C  CA  . GLU A 1 27  ? 226.167 223.359 317.809 1.00 146.87 ? 27  GLU A CA  1 
ATOM   57    C  C   . GLU A 1 27  ? 225.991 224.380 316.694 1.00 146.87 ? 27  GLU A C   1 
ATOM   58    O  O   . GLU A 1 27  ? 224.867 224.662 316.265 1.00 146.87 ? 27  GLU A O   1 
ATOM   59    C  CB  . GLU A 1 27  ? 226.228 224.055 319.168 1.00 146.87 ? 27  GLU A CB  1 
ATOM   60    C  CG  . GLU A 1 27  ? 225.685 223.233 320.323 1.00 146.87 ? 27  GLU A CG  1 
ATOM   61    C  CD  . GLU A 1 27  ? 224.178 223.341 320.459 1.00 146.87 ? 27  GLU A CD  1 
ATOM   62    O  OE1 . GLU A 1 27  ? 223.658 224.476 320.444 1.00 146.87 ? 27  GLU A OE1 1 
ATOM   63    O  OE2 . GLU A 1 27  ? 223.515 222.292 320.585 1.00 146.87 ? 27  GLU A OE2 1 
ATOM   64    N  N   . GLN A 1 28  ? 227.096 224.935 316.206 1.00 148.50 ? 28  GLN A N   1 
ATOM   65    C  CA  . GLN A 1 28  ? 227.086 225.937 315.152 1.00 148.50 ? 28  GLN A CA  1 
ATOM   66    C  C   . GLN A 1 28  ? 227.236 225.336 313.759 1.00 148.50 ? 28  GLN A C   1 
ATOM   67    O  O   . GLN A 1 28  ? 227.340 226.086 312.783 1.00 148.50 ? 28  GLN A O   1 
ATOM   68    C  CB  . GLN A 1 28  ? 228.198 226.958 315.399 1.00 148.50 ? 28  GLN A CB  1 
ATOM   69    C  CG  . GLN A 1 28  ? 228.311 227.404 316.846 1.00 148.50 ? 28  GLN A CG  1 
ATOM   70    C  CD  . GLN A 1 28  ? 229.329 228.510 317.040 1.00 148.50 ? 28  GLN A CD  1 
ATOM   71    O  OE1 . GLN A 1 28  ? 229.587 229.300 316.131 1.00 148.50 ? 28  GLN A OE1 1 
ATOM   72    N  NE2 . GLN A 1 28  ? 229.915 228.572 318.230 1.00 148.50 ? 28  GLN A NE2 1 
ATOM   73    N  N   . ASN A 1 29  ? 227.253 224.012 313.645 1.00 144.57 ? 29  ASN A N   1 
ATOM   74    C  CA  . ASN A 1 29  ? 227.468 223.330 312.377 1.00 144.57 ? 29  ASN A CA  1 
ATOM   75    C  C   . ASN A 1 29  ? 226.147 223.059 311.666 1.00 144.57 ? 29  ASN A C   1 
ATOM   76    O  O   . ASN A 1 29  ? 225.079 222.994 312.280 1.00 144.57 ? 29  ASN A O   1 
ATOM   77    C  CB  . ASN A 1 29  ? 228.220 222.014 312.596 1.00 144.57 ? 29  ASN A CB  1 
ATOM   78    C  CG  . ASN A 1 29  ? 228.821 221.465 311.315 1.00 144.57 ? 29  ASN A CG  1 
ATOM   79    O  OD1 . ASN A 1 29  ? 228.122 221.270 310.319 1.00 144.57 ? 29  ASN A OD1 1 
ATOM   80    N  ND2 . ASN A 1 29  ? 230.127 221.222 311.332 1.00 144.57 ? 29  ASN A ND2 1 
ATOM   81    N  N   . MET A 1 30  ? 226.240 222.900 310.343 1.00 136.37 ? 30  MET A N   1 
ATOM   82    C  CA  . MET A 1 30  ? 225.093 222.506 309.534 1.00 136.37 ? 30  MET A CA  1 
ATOM   83    C  C   . MET A 1 30  ? 224.856 221.005 309.552 1.00 136.37 ? 30  MET A C   1 
ATOM   84    O  O   . MET A 1 30  ? 223.851 220.547 308.998 1.00 136.37 ? 30  MET A O   1 
ATOM   85    C  CB  . MET A 1 30  ? 225.279 222.982 308.095 1.00 136.37 ? 30  MET A CB  1 
ATOM   86    C  CG  . MET A 1 30  ? 226.502 222.402 307.408 1.00 136.37 ? 30  MET A CG  1 
ATOM   87    S  SD  . MET A 1 30  ? 226.481 222.658 305.626 1.00 136.37 ? 30  MET A SD  1 
ATOM   88    C  CE  . MET A 1 30  ? 225.994 221.034 305.054 1.00 136.37 ? 30  MET A CE  1 
ATOM   89    N  N   . MET A 1 31  ? 225.753 220.234 310.161 1.00 138.69 ? 31  MET A N   1 
ATOM   90    C  CA  . MET A 1 31  ? 225.559 218.796 310.284 1.00 138.69 ? 31  MET A CA  1 
ATOM   91    C  C   . MET A 1 31  ? 224.575 218.492 311.406 1.00 138.69 ? 31  MET A C   1 
ATOM   92    O  O   . MET A 1 31  ? 224.752 218.950 312.539 1.00 138.69 ? 31  MET A O   1 
ATOM   93    C  CB  . MET A 1 31  ? 226.897 218.110 310.566 1.00 138.69 ? 31  MET A CB  1 
ATOM   94    C  CG  . MET A 1 31  ? 226.946 216.622 310.241 1.00 138.69 ? 31  MET A CG  1 
ATOM   95    S  SD  . MET A 1 31  ? 227.509 216.282 308.562 1.00 138.69 ? 31  MET A SD  1 
ATOM   96    C  CE  . MET A 1 31  ? 226.861 214.634 308.303 1.00 138.69 ? 31  MET A CE  1 
ATOM   97    N  N   . GLY A 1 32  ? 223.535 217.717 311.099 1.00 141.65 ? 32  GLY A N   1 
ATOM   98    C  CA  . GLY A 1 32  ? 222.672 217.209 312.152 1.00 141.65 ? 32  GLY A CA  1 
ATOM   99    C  C   . GLY A 1 32  ? 223.397 216.122 312.929 1.00 141.65 ? 32  GLY A C   1 
ATOM   100   O  O   . GLY A 1 32  ? 224.149 215.330 312.367 1.00 141.65 ? 32  GLY A O   1 
ATOM   101   N  N   . ALA A 1 33  ? 223.159 216.081 314.237 1.00 149.43 ? 33  ALA A N   1 
ATOM   102   C  CA  . ALA A 1 33  ? 223.920 215.161 315.070 1.00 149.43 ? 33  ALA A CA  1 
ATOM   103   C  C   . ALA A 1 33  ? 223.082 214.701 316.253 1.00 149.43 ? 33  ALA A C   1 
ATOM   104   O  O   . ALA A 1 33  ? 222.395 215.502 316.893 1.00 149.43 ? 33  ALA A O   1 
ATOM   105   C  CB  . ALA A 1 33  ? 225.218 215.813 315.555 1.00 149.43 ? 33  ALA A CB  1 
ATOM   106   N  N   . VAL A 1 34  ? 223.150 213.400 316.533 1.00 153.71 ? 34  VAL A N   1 
ATOM   107   C  CA  . VAL A 1 34  ? 222.496 212.799 317.693 1.00 153.71 ? 34  VAL A CA  1 
ATOM   108   C  C   . VAL A 1 34  ? 223.451 211.782 318.303 1.00 153.71 ? 34  VAL A C   1 
ATOM   109   O  O   . VAL A 1 34  ? 224.136 211.049 317.587 1.00 153.71 ? 34  VAL A O   1 
ATOM   110   C  CB  . VAL A 1 34  ? 221.149 212.142 317.311 1.00 153.71 ? 34  VAL A CB  1 
ATOM   111   C  CG1 . VAL A 1 34  ? 220.551 211.415 318.504 1.00 153.71 ? 34  VAL A CG1 1 
ATOM   112   C  CG2 . VAL A 1 34  ? 220.167 213.181 316.789 1.00 153.71 ? 34  VAL A CG2 1 
ATOM   113   N  N   . LEU A 1 35  ? 223.516 211.752 319.633 1.00 158.20 ? 35  LEU A N   1 
ATOM   114   C  CA  . LEU A 1 35  ? 224.272 210.736 320.356 1.00 158.20 ? 35  LEU A CA  1 
ATOM   115   C  C   . LEU A 1 35  ? 223.372 210.126 321.417 1.00 158.20 ? 35  LEU A C   1 
ATOM   116   O  O   . LEU A 1 35  ? 222.705 210.854 322.159 1.00 158.20 ? 35  LEU A O   1 
ATOM   117   C  CB  . LEU A 1 35  ? 225.531 211.322 321.004 1.00 158.20 ? 35  LEU A CB  1 
ATOM   118   C  CG  . LEU A 1 35  ? 226.387 210.383 321.859 1.00 158.20 ? 35  LEU A CG  1 
ATOM   119   C  CD1 . LEU A 1 35  ? 226.953 209.246 321.029 1.00 158.20 ? 35  LEU A CD1 1 
ATOM   120   C  CD2 . LEU A 1 35  ? 227.505 211.153 322.546 1.00 158.20 ? 35  LEU A CD2 1 
ATOM   121   N  N   . ILE A 1 36  ? 223.351 208.798 321.491 1.00 161.23 ? 36  ILE A N   1 
ATOM   122   C  CA  . ILE A 1 36  ? 222.511 208.089 322.447 1.00 161.23 ? 36  ILE A CA  1 
ATOM   123   C  C   . ILE A 1 36  ? 223.391 207.252 323.363 1.00 161.23 ? 36  ILE A C   1 
ATOM   124   O  O   . ILE A 1 36  ? 224.317 206.566 322.909 1.00 161.23 ? 36  ILE A O   1 
ATOM   125   C  CB  . ILE A 1 36  ? 221.443 207.217 321.756 1.00 161.23 ? 36  ILE A CB  1 
ATOM   126   C  CG1 . ILE A 1 36  ? 222.073 206.265 320.740 1.00 161.23 ? 36  ILE A CG1 1 
ATOM   127   C  CG2 . ILE A 1 36  ? 220.412 208.096 321.084 1.00 161.23 ? 36  ILE A CG2 1 
ATOM   128   C  CD1 . ILE A 1 36  ? 221.202 205.067 320.420 1.00 161.23 ? 36  ILE A CD1 1 
ATOM   129   N  N   . ASN A 1 37  ? 223.098 207.330 324.659 1.00 161.36 ? 37  ASN A N   1 
ATOM   130   C  CA  . ASN A 1 37  ? 223.830 206.635 325.705 1.00 161.36 ? 37  ASN A CA  1 
ATOM   131   C  C   . ASN A 1 37  ? 223.183 205.278 325.978 1.00 161.36 ? 37  ASN A C   1 
ATOM   132   O  O   . ASN A 1 37  ? 222.355 204.790 325.203 1.00 161.36 ? 37  ASN A O   1 
ATOM   133   C  CB  . ASN A 1 37  ? 223.888 207.497 326.963 1.00 161.36 ? 37  ASN A CB  1 
ATOM   134   C  CG  . ASN A 1 37  ? 222.512 207.840 327.497 1.00 161.36 ? 37  ASN A CG  1 
ATOM   135   O  OD1 . ASN A 1 37  ? 221.497 207.551 326.863 1.00 161.36 ? 37  ASN A OD1 1 
ATOM   136   N  ND2 . ASN A 1 37  ? 222.472 208.462 328.669 1.00 161.36 ? 37  ASN A ND2 1 
ATOM   137   N  N   . GLU A 1 38  ? 223.567 204.652 327.092 1.00 164.33 ? 38  GLU A N   1 
ATOM   138   C  CA  . GLU A 1 38  ? 223.013 203.351 327.452 1.00 164.33 ? 38  GLU A CA  1 
ATOM   139   C  C   . GLU A 1 38  ? 221.499 203.422 327.603 1.00 164.33 ? 38  GLU A C   1 
ATOM   140   O  O   . GLU A 1 38  ? 220.768 202.568 327.088 1.00 164.33 ? 38  GLU A O   1 
ATOM   141   C  CB  . GLU A 1 38  ? 223.654 202.855 328.749 1.00 164.33 ? 38  GLU A CB  1 
ATOM   142   C  CG  . GLU A 1 38  ? 225.171 202.816 328.725 1.00 164.33 ? 38  GLU A CG  1 
ATOM   143   C  CD  . GLU A 1 38  ? 225.711 201.615 327.980 1.00 164.33 ? 38  GLU A CD  1 
ATOM   144   O  OE1 . GLU A 1 38  ? 225.178 200.503 328.176 1.00 164.33 ? 38  GLU A OE1 1 
ATOM   145   O  OE2 . GLU A 1 38  ? 226.672 201.781 327.200 1.00 164.33 ? 38  GLU A OE2 1 
ATOM   146   N  N   . ASN A 1 39  ? 221.009 204.446 328.301 1.00 164.29 ? 39  ASN A N   1 
ATOM   147   C  CA  . ASN A 1 39  ? 219.581 204.638 328.513 1.00 164.29 ? 39  ASN A CA  1 
ATOM   148   C  C   . ASN A 1 39  ? 218.911 205.382 327.367 1.00 164.29 ? 39  ASN A C   1 
ATOM   149   O  O   . ASN A 1 39  ? 217.793 205.886 327.539 1.00 164.29 ? 39  ASN A O   1 
ATOM   150   C  CB  . ASN A 1 39  ? 219.339 205.378 329.831 1.00 164.29 ? 39  ASN A CB  1 
ATOM   151   C  CG  . ASN A 1 39  ? 219.757 204.564 331.040 1.00 164.29 ? 39  ASN A CG  1 
ATOM   152   O  OD1 . ASN A 1 39  ? 220.893 204.659 331.505 1.00 164.29 ? 39  ASN A OD1 1 
ATOM   153   N  ND2 . ASN A 1 39  ? 218.836 203.759 331.558 1.00 164.29 ? 39  ASN A ND2 1 
ATOM   154   N  N   . ASP A 1 40  ? 219.576 205.473 326.216 1.00 160.81 ? 40  ASP A N   1 
ATOM   155   C  CA  . ASP A 1 40  ? 219.042 206.109 325.015 1.00 160.81 ? 40  ASP A CA  1 
ATOM   156   C  C   . ASP A 1 40  ? 218.722 207.584 325.231 1.00 160.81 ? 40  ASP A C   1 
ATOM   157   O  O   . ASP A 1 40  ? 218.015 208.191 324.422 1.00 160.81 ? 40  ASP A O   1 
ATOM   158   C  CB  . ASP A 1 40  ? 217.801 205.372 324.501 1.00 160.81 ? 40  ASP A CB  1 
ATOM   159   C  CG  . ASP A 1 40  ? 218.062 203.903 324.242 1.00 160.81 ? 40  ASP A CG  1 
ATOM   160   O  OD1 . ASP A 1 40  ? 219.236 203.535 324.024 1.00 160.81 ? 40  ASP A OD1 1 
ATOM   161   O  OD2 . ASP A 1 40  ? 217.094 203.115 324.255 1.00 160.81 ? 40  ASP A OD2 1 
ATOM   162   N  N   . GLU A 1 41  ? 219.234 208.177 326.305 1.00 160.72 ? 41  GLU A N   1 
ATOM   163   C  CA  . GLU A 1 41  ? 219.013 209.588 326.586 1.00 160.72 ? 41  GLU A CA  1 
ATOM   164   C  C   . GLU A 1 41  ? 220.016 210.423 325.804 1.00 160.72 ? 41  GLU A C   1 
ATOM   165   O  O   . GLU A 1 41  ? 221.230 210.237 325.938 1.00 160.72 ? 41  GLU A O   1 
ATOM   166   C  CB  . GLU A 1 41  ? 219.134 209.864 328.084 1.00 160.72 ? 41  GLU A CB  1 
ATOM   167   C  CG  . GLU A 1 41  ? 218.204 209.017 328.939 1.00 160.72 ? 41  GLU A CG  1 
ATOM   168   C  CD  . GLU A 1 41  ? 218.535 209.096 330.417 1.00 160.72 ? 41  GLU A CD  1 
ATOM   169   O  OE1 . GLU A 1 41  ? 219.731 209.219 330.754 1.00 160.72 ? 41  GLU A OE1 1 
ATOM   170   O  OE2 . GLU A 1 41  ? 217.599 209.035 331.242 1.00 160.72 ? 41  GLU A OE2 1 
ATOM   171   N  N   . VAL A 1 42  ? 219.506 211.338 324.990 1.00 160.23 ? 42  VAL A N   1 
ATOM   172   C  CA  . VAL A 1 42  ? 220.349 212.121 324.095 1.00 160.23 ? 42  VAL A CA  1 
ATOM   173   C  C   . VAL A 1 42  ? 220.992 213.264 324.865 1.00 160.23 ? 42  VAL A C   1 
ATOM   174   O  O   . VAL A 1 42  ? 220.315 214.022 325.570 1.00 160.23 ? 42  VAL A O   1 
ATOM   175   C  CB  . VAL A 1 42  ? 219.529 212.644 322.903 1.00 160.23 ? 42  VAL A CB  1 
ATOM   176   C  CG1 . VAL A 1 42  ? 220.444 213.297 321.877 1.00 160.23 ? 42  VAL A CG1 1 
ATOM   177   C  CG2 . VAL A 1 42  ? 218.727 211.514 322.277 1.00 160.23 ? 42  VAL A CG2 1 
ATOM   178   N  N   . MET A 1 43  ? 222.315 213.385 324.734 1.00 157.99 ? 43  MET A N   1 
ATOM   179   C  CA  . MET A 1 43  ? 223.043 214.494 325.338 1.00 157.99 ? 43  MET A CA  1 
ATOM   180   C  C   . MET A 1 43  ? 223.883 215.252 324.313 1.00 157.99 ? 43  MET A C   1 
ATOM   181   O  O   . MET A 1 43  ? 224.819 215.964 324.697 1.00 157.99 ? 43  MET A O   1 
ATOM   182   C  CB  . MET A 1 43  ? 223.938 213.999 326.479 1.00 157.99 ? 43  MET A CB  1 
ATOM   183   C  CG  . MET A 1 43  ? 225.027 213.032 326.040 1.00 157.99 ? 43  MET A CG  1 
ATOM   184   S  SD  . MET A 1 43  ? 226.012 212.413 327.417 1.00 157.99 ? 43  MET A SD  1 
ATOM   185   C  CE  . MET A 1 43  ? 224.862 211.272 328.181 1.00 157.99 ? 43  MET A CE  1 
ATOM   186   N  N   . PHE A 1 44  ? 223.576 215.115 323.022 1.00 153.17 ? 44  PHE A N   1 
ATOM   187   C  CA  . PHE A 1 44  ? 224.395 215.708 321.962 1.00 153.17 ? 44  PHE A CA  1 
ATOM   188   C  C   . PHE A 1 44  ? 223.456 216.003 320.789 1.00 153.17 ? 44  PHE A C   1 
ATOM   189   O  O   . PHE A 1 44  ? 223.212 215.145 319.938 1.00 153.17 ? 44  PHE A O   1 
ATOM   190   C  CB  . PHE A 1 44  ? 225.527 214.763 321.581 1.00 153.17 ? 44  PHE A CB  1 
ATOM   191   C  CG  . PHE A 1 44  ? 226.274 215.148 320.338 1.00 153.17 ? 44  PHE A CG  1 
ATOM   192   C  CD1 . PHE A 1 44  ? 226.896 216.379 320.241 1.00 153.17 ? 44  PHE A CD1 1 
ATOM   193   C  CD2 . PHE A 1 44  ? 226.378 214.271 319.282 1.00 153.17 ? 44  PHE A CD2 1 
ATOM   194   C  CE1 . PHE A 1 44  ? 227.590 216.732 319.106 1.00 153.17 ? 44  PHE A CE1 1 
ATOM   195   C  CE2 . PHE A 1 44  ? 227.074 214.617 318.147 1.00 153.17 ? 44  PHE A CE2 1 
ATOM   196   C  CZ  . PHE A 1 44  ? 227.679 215.849 318.057 1.00 153.17 ? 44  PHE A CZ  1 
ATOM   197   N  N   . PHE A 1 45  ? 222.941 217.229 320.759 1.00 147.92 ? 45  PHE A N   1 
ATOM   198   C  CA  . PHE A 1 45  ? 221.852 217.610 319.870 1.00 147.92 ? 45  PHE A CA  1 
ATOM   199   C  C   . PHE A 1 45  ? 221.975 219.099 319.587 1.00 147.92 ? 45  PHE A C   1 
ATOM   200   O  O   . PHE A 1 45  ? 222.205 219.885 320.510 1.00 147.92 ? 45  PHE A O   1 
ATOM   201   C  CB  . PHE A 1 45  ? 220.507 217.275 320.521 1.00 147.92 ? 45  PHE A CB  1 
ATOM   202   C  CG  . PHE A 1 45  ? 219.344 217.278 319.582 1.00 147.92 ? 45  PHE A CG  1 
ATOM   203   C  CD1 . PHE A 1 45  ? 218.678 218.455 319.288 1.00 147.92 ? 45  PHE A CD1 1 
ATOM   204   C  CD2 . PHE A 1 45  ? 218.896 216.099 319.010 1.00 147.92 ? 45  PHE A CD2 1 
ATOM   205   C  CE1 . PHE A 1 45  ? 217.590 218.456 318.433 1.00 147.92 ? 45  PHE A CE1 1 
ATOM   206   C  CE2 . PHE A 1 45  ? 217.812 216.095 318.153 1.00 147.92 ? 45  PHE A CE2 1 
ATOM   207   C  CZ  . PHE A 1 45  ? 217.157 217.274 317.866 1.00 147.92 ? 45  PHE A CZ  1 
ATOM   208   N  N   . ASN A 1 46  ? 221.816 219.480 318.322 1.00 145.25 ? 46  ASN A N   1 
ATOM   209   C  CA  . ASN A 1 46  ? 222.199 220.809 317.858 1.00 145.25 ? 46  ASN A CA  1 
ATOM   210   C  C   . ASN A 1 46  ? 221.007 221.532 317.248 1.00 145.25 ? 46  ASN A C   1 
ATOM   211   O  O   . ASN A 1 46  ? 220.002 220.893 316.922 1.00 145.25 ? 46  ASN A O   1 
ATOM   212   C  CB  . ASN A 1 46  ? 223.329 220.703 316.833 1.00 145.25 ? 46  ASN A CB  1 
ATOM   213   C  CG  . ASN A 1 46  ? 224.637 220.277 317.454 1.00 145.25 ? 46  ASN A CG  1 
ATOM   214   O  OD1 . ASN A 1 46  ? 224.895 220.538 318.627 1.00 145.25 ? 46  ASN A OD1 1 
ATOM   215   N  ND2 . ASN A 1 46  ? 225.475 219.614 316.667 1.00 145.25 ? 46  ASN A ND2 1 
ATOM   216   N  N   . PRO A 1 47  ? 221.072 222.859 317.090 1.00 145.94 ? 47  PRO A N   1 
ATOM   217   C  CA  . PRO A 1 47  ? 219.966 223.569 316.422 1.00 145.94 ? 47  PRO A CA  1 
ATOM   218   C  C   . PRO A 1 47  ? 219.700 223.083 315.008 1.00 145.94 ? 47  PRO A C   1 
ATOM   219   O  O   . PRO A 1 47  ? 218.555 223.149 314.543 1.00 145.94 ? 47  PRO A O   1 
ATOM   220   C  CB  . PRO A 1 47  ? 220.431 225.032 316.438 1.00 145.94 ? 47  PRO A CB  1 
ATOM   221   C  CG  . PRO A 1 47  ? 221.380 225.114 317.582 1.00 145.94 ? 47  PRO A CG  1 
ATOM   222   C  CD  . PRO A 1 47  ? 222.073 223.788 317.643 1.00 145.94 ? 47  PRO A CD  1 
ATOM   223   N  N   . ALA A 1 48  ? 220.724 222.598 314.305 1.00 142.72 ? 48  ALA A N   1 
ATOM   224   C  CA  . ALA A 1 48  ? 220.484 221.954 313.020 1.00 142.72 ? 48  ALA A CA  1 
ATOM   225   C  C   . ALA A 1 48  ? 219.572 220.746 313.188 1.00 142.72 ? 48  ALA A C   1 
ATOM   226   O  O   . ALA A 1 48  ? 218.620 220.556 312.421 1.00 142.72 ? 48  ALA A O   1 
ATOM   227   C  CB  . ALA A 1 48  ? 221.812 221.546 312.383 1.00 142.72 ? 48  ALA A CB  1 
ATOM   228   N  N   . ALA A 1 49  ? 219.836 219.927 314.208 1.00 142.55 ? 49  ALA A N   1 
ATOM   229   C  CA  . ALA A 1 49  ? 218.976 218.781 314.475 1.00 142.55 ? 49  ALA A CA  1 
ATOM   230   C  C   . ALA A 1 49  ? 217.583 219.232 314.897 1.00 142.55 ? 49  ALA A C   1 
ATOM   231   O  O   . ALA A 1 49  ? 216.582 218.578 314.577 1.00 142.55 ? 49  ALA A O   1 
ATOM   232   C  CB  . ALA A 1 49  ? 219.612 217.896 315.545 1.00 142.55 ? 49  ALA A CB  1 
ATOM   233   N  N   . GLU A 1 50  ? 217.501 220.351 315.617 1.00 147.26 ? 50  GLU A N   1 
ATOM   234   C  CA  . GLU A 1 50  ? 216.203 220.906 315.984 1.00 147.26 ? 50  GLU A CA  1 
ATOM   235   C  C   . GLU A 1 50  ? 215.399 221.259 314.743 1.00 147.26 ? 50  GLU A C   1 
ATOM   236   O  O   . GLU A 1 50  ? 214.206 220.952 314.651 1.00 147.26 ? 50  GLU A O   1 
ATOM   237   C  CB  . GLU A 1 50  ? 216.389 222.141 316.866 1.00 147.26 ? 50  GLU A CB  1 
ATOM   238   C  CG  . GLU A 1 50  ? 216.753 221.845 318.306 1.00 147.26 ? 50  GLU A CG  1 
ATOM   239   C  CD  . GLU A 1 50  ? 216.623 223.068 319.189 1.00 147.26 ? 50  GLU A CD  1 
ATOM   240   O  OE1 . GLU A 1 50  ? 216.645 224.195 318.650 1.00 147.26 ? 50  GLU A OE1 1 
ATOM   241   O  OE2 . GLU A 1 50  ? 216.489 222.905 320.418 1.00 147.26 ? 50  GLU A OE2 1 
ATOM   242   N  N   . LYS A 1 51  ? 216.042 221.904 313.772 1.00 143.25 ? 51  LYS A N   1 
ATOM   243   C  CA  . LYS A 1 51  ? 215.362 222.195 312.516 1.00 143.25 ? 51  LYS A CA  1 
ATOM   244   C  C   . LYS A 1 51  ? 214.970 220.909 311.804 1.00 143.25 ? 51  LYS A C   1 
ATOM   245   O  O   . LYS A 1 51  ? 213.875 220.811 311.237 1.00 143.25 ? 51  LYS A O   1 
ATOM   246   C  CB  . LYS A 1 51  ? 216.250 223.054 311.618 1.00 143.25 ? 51  LYS A CB  1 
ATOM   247   C  CG  . LYS A 1 51  ? 216.039 224.547 311.783 1.00 143.25 ? 51  LYS A CG  1 
ATOM   248   C  CD  . LYS A 1 51  ? 216.973 225.337 310.880 1.00 143.25 ? 51  LYS A CD  1 
ATOM   249   C  CE  . LYS A 1 51  ? 218.422 224.927 311.089 1.00 143.25 ? 51  LYS A CE  1 
ATOM   250   N  NZ  . LYS A 1 51  ? 218.816 224.978 312.523 1.00 143.25 ? 51  LYS A NZ  1 
ATOM   251   N  N   . LEU A 1 52  ? 215.851 219.908 311.833 1.00 140.63 ? 52  LEU A N   1 
ATOM   252   C  CA  . LEU A 1 52  ? 215.605 218.678 311.089 1.00 140.63 ? 52  LEU A CA  1 
ATOM   253   C  C   . LEU A 1 52  ? 214.389 217.934 311.629 1.00 140.63 ? 52  LEU A C   1 
ATOM   254   O  O   . LEU A 1 52  ? 213.544 217.462 310.860 1.00 140.63 ? 52  LEU A O   1 
ATOM   255   C  CB  . LEU A 1 52  ? 216.847 217.786 311.132 1.00 140.63 ? 52  LEU A CB  1 
ATOM   256   C  CG  . LEU A 1 52  ? 217.964 218.127 310.144 1.00 140.63 ? 52  LEU A CG  1 
ATOM   257   C  CD1 . LEU A 1 52  ? 219.252 217.409 310.520 1.00 140.63 ? 52  LEU A CD1 1 
ATOM   258   C  CD2 . LEU A 1 52  ? 217.551 217.785 308.720 1.00 140.63 ? 52  LEU A CD2 1 
ATOM   259   N  N   . TRP A 1 53  ? 214.282 217.819 312.952 1.00 143.13 ? 53  TRP A N   1 
ATOM   260   C  CA  . TRP A 1 53  ? 213.183 217.076 313.564 1.00 143.13 ? 53  TRP A CA  1 
ATOM   261   C  C   . TRP A 1 53  ? 212.004 217.955 313.967 1.00 143.13 ? 53  TRP A C   1 
ATOM   262   O  O   . TRP A 1 53  ? 210.897 217.779 313.450 1.00 143.13 ? 53  TRP A O   1 
ATOM   263   C  CB  . TRP A 1 53  ? 213.681 216.291 314.784 1.00 143.13 ? 53  TRP A CB  1 
ATOM   264   C  CG  . TRP A 1 53  ? 214.388 215.018 314.440 1.00 143.13 ? 53  TRP A CG  1 
ATOM   265   C  CD1 . TRP A 1 53  ? 213.817 213.789 314.275 1.00 143.13 ? 53  TRP A CD1 1 
ATOM   266   C  CD2 . TRP A 1 53  ? 215.793 214.836 314.242 1.00 143.13 ? 53  TRP A CD2 1 
ATOM   267   N  NE1 . TRP A 1 53  ? 214.778 212.856 313.974 1.00 143.13 ? 53  TRP A NE1 1 
ATOM   268   C  CE2 . TRP A 1 53  ? 216.000 213.473 313.949 1.00 143.13 ? 53  TRP A CE2 1 
ATOM   269   C  CE3 . TRP A 1 53  ? 216.896 215.691 314.280 1.00 143.13 ? 53  TRP A CE3 1 
ATOM   270   C  CZ2 . TRP A 1 53  ? 217.265 212.948 313.695 1.00 143.13 ? 53  TRP A CZ2 1 
ATOM   271   C  CZ3 . TRP A 1 53  ? 218.149 215.168 314.025 1.00 143.13 ? 53  TRP A CZ3 1 
ATOM   272   C  CH2 . TRP A 1 53  ? 218.324 213.811 313.738 1.00 143.13 ? 53  TRP A CH2 1 
ATOM   273   N  N   . GLY A 1 54  ? 212.215 218.901 314.878 1.00 145.46 ? 54  GLY A N   1 
ATOM   274   C  CA  . GLY A 1 54  ? 211.149 219.726 315.409 1.00 145.46 ? 54  GLY A CA  1 
ATOM   275   C  C   . GLY A 1 54  ? 211.071 219.756 316.920 1.00 145.46 ? 54  GLY A C   1 
ATOM   276   O  O   . GLY A 1 54  ? 210.374 220.619 317.469 1.00 145.46 ? 54  GLY A O   1 
ATOM   277   N  N   . TYR A 1 55  ? 211.755 218.847 317.608 1.00 149.20 ? 55  TYR A N   1 
ATOM   278   C  CA  . TYR A 1 55  ? 211.792 218.841 319.062 1.00 149.20 ? 55  TYR A CA  1 
ATOM   279   C  C   . TYR A 1 55  ? 212.868 219.795 319.566 1.00 149.20 ? 55  TYR A C   1 
ATOM   280   O  O   . TYR A 1 55  ? 213.899 219.997 318.920 1.00 149.20 ? 55  TYR A O   1 
ATOM   281   C  CB  . TYR A 1 55  ? 212.051 217.429 319.591 1.00 149.20 ? 55  TYR A CB  1 
ATOM   282   C  CG  . TYR A 1 55  ? 210.853 216.510 319.504 1.00 149.20 ? 55  TYR A CG  1 
ATOM   283   C  CD1 . TYR A 1 55  ? 210.481 215.933 318.297 1.00 149.20 ? 55  TYR A CD1 1 
ATOM   284   C  CD2 . TYR A 1 55  ? 210.097 216.215 320.631 1.00 149.20 ? 55  TYR A CD2 1 
ATOM   285   C  CE1 . TYR A 1 55  ? 209.388 215.090 318.214 1.00 149.20 ? 55  TYR A CE1 1 
ATOM   286   C  CE2 . TYR A 1 55  ? 209.002 215.374 320.558 1.00 149.20 ? 55  TYR A CE2 1 
ATOM   287   C  CZ  . TYR A 1 55  ? 208.653 214.814 319.347 1.00 149.20 ? 55  TYR A CZ  1 
ATOM   288   O  OH  . TYR A 1 55  ? 207.564 213.977 319.269 1.00 149.20 ? 55  TYR A OH  1 
ATOM   289   N  N   . LYS A 1 56  ? 212.618 220.380 320.733 1.00 147.34 ? 56  LYS A N   1 
ATOM   290   C  CA  . LYS A 1 56  ? 213.510 221.385 321.291 1.00 147.34 ? 56  LYS A CA  1 
ATOM   291   C  C   . LYS A 1 56  ? 214.610 220.740 322.124 1.00 147.34 ? 56  LYS A C   1 
ATOM   292   O  O   . LYS A 1 56  ? 214.497 219.592 322.563 1.00 147.34 ? 56  LYS A O   1 
ATOM   293   C  CB  . LYS A 1 56  ? 212.730 222.386 322.145 1.00 147.34 ? 56  LYS A CB  1 
ATOM   294   C  CG  . LYS A 1 56  ? 212.035 223.470 321.338 1.00 147.34 ? 56  LYS A CG  1 
ATOM   295   C  CD  . LYS A 1 56  ? 213.039 224.461 320.770 1.00 147.34 ? 56  LYS A CD  1 
ATOM   296   C  CE  . LYS A 1 56  ? 212.490 225.163 319.539 1.00 147.34 ? 56  LYS A CE  1 
ATOM   297   N  NZ  . LYS A 1 56  ? 213.522 226.005 318.874 1.00 147.34 ? 56  LYS A NZ  1 
ATOM   298   N  N   . ARG A 1 57  ? 215.686 221.503 322.336 1.00 148.02 ? 57  ARG A N   1 
ATOM   299   C  CA  . ARG A 1 57  ? 216.820 220.998 323.102 1.00 148.02 ? 57  ARG A CA  1 
ATOM   300   C  C   . ARG A 1 57  ? 216.412 220.654 324.527 1.00 148.02 ? 57  ARG A C   1 
ATOM   301   O  O   . ARG A 1 57  ? 216.842 219.634 325.077 1.00 148.02 ? 57  ARG A O   1 
ATOM   302   C  CB  . ARG A 1 57  ? 217.953 222.026 323.098 1.00 148.02 ? 57  ARG A CB  1 
ATOM   303   C  CG  . ARG A 1 57  ? 219.165 221.628 323.922 1.00 148.02 ? 57  ARG A CG  1 
ATOM   304   C  CD  . ARG A 1 57  ? 220.243 222.698 323.871 1.00 148.02 ? 57  ARG A CD  1 
ATOM   305   N  NE  . ARG A 1 57  ? 219.784 223.966 324.425 1.00 148.02 ? 57  ARG A NE  1 
ATOM   306   C  CZ  . ARG A 1 57  ? 220.368 225.136 324.204 1.00 148.02 ? 57  ARG A CZ  1 
ATOM   307   N  NH1 . ARG A 1 57  ? 221.445 225.237 323.441 1.00 148.02 ? 57  ARG A NH1 1 
ATOM   308   N  NH2 . ARG A 1 57  ? 219.860 226.231 324.762 1.00 148.02 ? 57  ARG A NH2 1 
ATOM   309   N  N   . GLU A 1 58  ? 215.581 221.497 325.142 1.00 151.60 ? 58  GLU A N   1 
ATOM   310   C  CA  . GLU A 1 58  ? 215.075 221.196 326.475 1.00 151.60 ? 58  GLU A CA  1 
ATOM   311   C  C   . GLU A 1 58  ? 214.192 219.956 326.484 1.00 151.60 ? 58  GLU A C   1 
ATOM   312   O  O   . GLU A 1 58  ? 214.115 219.270 327.509 1.00 151.60 ? 58  GLU A O   1 
ATOM   313   C  CB  . GLU A 1 58  ? 214.299 222.394 327.029 1.00 151.60 ? 58  GLU A CB  1 
ATOM   314   C  CG  . GLU A 1 58  ? 215.169 223.576 327.437 1.00 151.60 ? 58  GLU A CG  1 
ATOM   315   C  CD  . GLU A 1 58  ? 215.703 224.353 326.248 1.00 151.60 ? 58  GLU A CD  1 
ATOM   316   O  OE1 . GLU A 1 58  ? 215.027 224.372 325.197 1.00 151.60 ? 58  GLU A OE1 1 
ATOM   317   O  OE2 . GLU A 1 58  ? 216.797 224.944 326.364 1.00 151.60 ? 58  GLU A OE2 1 
ATOM   318   N  N   . GLU A 1 59  ? 213.529 219.654 325.369 1.00 148.57 ? 59  GLU A N   1 
ATOM   319   C  CA  . GLU A 1 59  ? 212.681 218.475 325.265 1.00 148.57 ? 59  GLU A CA  1 
ATOM   320   C  C   . GLU A 1 59  ? 213.447 217.221 324.872 1.00 148.57 ? 59  GLU A C   1 
ATOM   321   O  O   . GLU A 1 59  ? 212.896 216.121 324.976 1.00 148.57 ? 59  GLU A O   1 
ATOM   322   C  CB  . GLU A 1 59  ? 211.563 218.719 324.246 1.00 148.57 ? 59  GLU A CB  1 
ATOM   323   C  CG  . GLU A 1 59  ? 210.877 220.067 324.382 1.00 148.57 ? 59  GLU A CG  1 
ATOM   324   C  CD  . GLU A 1 59  ? 209.821 220.292 323.317 1.00 148.57 ? 59  GLU A CD  1 
ATOM   325   O  OE1 . GLU A 1 59  ? 210.156 220.198 322.118 1.00 148.57 ? 59  GLU A OE1 1 
ATOM   326   O  OE2 . GLU A 1 59  ? 208.657 220.565 323.680 1.00 148.57 ? 59  GLU A OE2 1 
ATOM   327   N  N   . VAL A 1 60  ? 214.691 217.358 324.420 1.00 153.11 ? 60  VAL A N   1 
ATOM   328   C  CA  . VAL A 1 60  ? 215.485 216.238 323.930 1.00 153.11 ? 60  VAL A CA  1 
ATOM   329   C  C   . VAL A 1 60  ? 216.559 215.832 324.931 1.00 153.11 ? 60  VAL A C   1 
ATOM   330   O  O   . VAL A 1 60  ? 216.710 214.647 325.249 1.00 153.11 ? 60  VAL A O   1 
ATOM   331   C  CB  . VAL A 1 60  ? 216.114 216.554 322.554 1.00 153.11 ? 60  VAL A CB  1 
ATOM   332   C  CG1 . VAL A 1 60  ? 217.166 215.515 322.198 1.00 153.11 ? 60  VAL A CG1 1 
ATOM   333   C  CG2 . VAL A 1 60  ? 215.040 216.607 321.483 1.00 153.11 ? 60  VAL A CG2 1 
ATOM   334   N  N   . ILE A 1 61  ? 217.318 216.802 325.439 1.00 155.14 ? 61  ILE A N   1 
ATOM   335   C  CA  . ILE A 1 61  ? 218.455 216.524 326.310 1.00 155.14 ? 61  ILE A CA  1 
ATOM   336   C  C   . ILE A 1 61  ? 217.982 215.772 327.546 1.00 155.14 ? 61  ILE A C   1 
ATOM   337   O  O   . ILE A 1 61  ? 217.111 216.247 328.283 1.00 155.14 ? 61  ILE A O   1 
ATOM   338   C  CB  . ILE A 1 61  ? 219.189 217.820 326.700 1.00 155.14 ? 61  ILE A CB  1 
ATOM   339   C  CG1 . ILE A 1 61  ? 219.871 218.432 325.477 1.00 155.14 ? 61  ILE A CG1 1 
ATOM   340   C  CG2 . ILE A 1 61  ? 220.206 217.547 327.798 1.00 155.14 ? 61  ILE A CG2 1 
ATOM   341   C  CD1 . ILE A 1 61  ? 220.956 217.563 324.882 1.00 155.14 ? 61  ILE A CD1 1 
ATOM   342   N  N   . GLY A 1 62  ? 218.553 214.592 327.776 1.00 158.39 ? 62  GLY A N   1 
ATOM   343   C  CA  . GLY A 1 62  ? 218.140 213.746 328.873 1.00 158.39 ? 62  GLY A CA  1 
ATOM   344   C  C   . GLY A 1 62  ? 216.915 212.904 328.602 1.00 158.39 ? 62  GLY A C   1 
ATOM   345   O  O   . GLY A 1 62  ? 216.454 212.202 329.512 1.00 158.39 ? 62  GLY A O   1 
ATOM   346   N  N   . ASN A 1 63  ? 216.372 212.948 327.390 1.00 156.23 ? 63  ASN A N   1 
ATOM   347   C  CA  . ASN A 1 63  ? 215.183 212.190 327.033 1.00 156.23 ? 63  ASN A CA  1 
ATOM   348   C  C   . ASN A 1 63  ? 215.556 211.055 326.093 1.00 156.23 ? 63  ASN A C   1 
ATOM   349   O  O   . ASN A 1 63  ? 216.504 211.169 325.312 1.00 156.23 ? 63  ASN A O   1 
ATOM   350   C  CB  . ASN A 1 63  ? 214.139 213.092 326.374 1.00 156.23 ? 63  ASN A CB  1 
ATOM   351   C  CG  . ASN A 1 63  ? 213.850 214.334 327.187 1.00 156.23 ? 63  ASN A CG  1 
ATOM   352   O  OD1 . ASN A 1 63  ? 214.575 215.324 327.107 1.00 156.23 ? 63  ASN A OD1 1 
ATOM   353   N  ND2 . ASN A 1 63  ? 212.783 214.291 327.975 1.00 156.23 ? 63  ASN A ND2 1 
ATOM   354   N  N   . ASN A 1 64  ? 214.806 209.958 326.177 1.00 157.54 ? 64  ASN A N   1 
ATOM   355   C  CA  . ASN A 1 64  ? 215.047 208.824 325.296 1.00 157.54 ? 64  ASN A CA  1 
ATOM   356   C  C   . ASN A 1 64  ? 214.809 209.221 323.846 1.00 157.54 ? 64  ASN A C   1 
ATOM   357   O  O   . ASN A 1 64  ? 213.884 209.978 323.537 1.00 157.54 ? 64  ASN A O   1 
ATOM   358   C  CB  . ASN A 1 64  ? 214.145 207.652 325.676 1.00 157.54 ? 64  ASN A CB  1 
ATOM   359   C  CG  . ASN A 1 64  ? 214.569 206.356 325.012 1.00 157.54 ? 64  ASN A CG  1 
ATOM   360   O  OD1 . ASN A 1 64  ? 214.724 206.288 323.792 1.00 157.54 ? 64  ASN A OD1 1 
ATOM   361   N  ND2 . ASN A 1 64  ? 214.759 205.317 325.816 1.00 157.54 ? 64  ASN A ND2 1 
ATOM   362   N  N   . ILE A 1 65  ? 215.651 208.699 322.952 1.00 158.20 ? 65  ILE A N   1 
ATOM   363   C  CA  . ILE A 1 65  ? 215.546 209.051 321.539 1.00 158.20 ? 65  ILE A CA  1 
ATOM   364   C  C   . ILE A 1 65  ? 214.307 208.418 320.921 1.00 158.20 ? 65  ILE A C   1 
ATOM   365   O  O   . ILE A 1 65  ? 213.827 208.858 319.868 1.00 158.20 ? 65  ILE A O   1 
ATOM   366   C  CB  . ILE A 1 65  ? 216.824 208.636 320.787 1.00 158.20 ? 65  ILE A CB  1 
ATOM   367   C  CG1 . ILE A 1 65  ? 216.832 209.229 319.376 1.00 158.20 ? 65  ILE A CG1 1 
ATOM   368   C  CG2 . ILE A 1 65  ? 216.938 207.119 320.729 1.00 158.20 ? 65  ILE A CG2 1 
ATOM   369   C  CD1 . ILE A 1 65  ? 218.006 208.798 318.532 1.00 158.20 ? 65  ILE A CD1 1 
ATOM   370   N  N   . ASP A 1 66  ? 213.758 207.386 321.572 1.00 155.22 ? 66  ASP A N   1 
ATOM   371   C  CA  . ASP A 1 66  ? 212.660 206.631 320.978 1.00 155.22 ? 66  ASP A CA  1 
ATOM   372   C  C   . ASP A 1 66  ? 211.475 207.526 320.646 1.00 155.22 ? 66  ASP A C   1 
ATOM   373   O  O   . ASP A 1 66  ? 210.683 207.202 319.756 1.00 155.22 ? 66  ASP A O   1 
ATOM   374   C  CB  . ASP A 1 66  ? 212.228 205.505 321.917 1.00 155.22 ? 66  ASP A CB  1 
ATOM   375   C  CG  . ASP A 1 66  ? 211.489 204.395 321.195 1.00 155.22 ? 66  ASP A CG  1 
ATOM   376   O  OD1 . ASP A 1 66  ? 211.347 204.477 319.957 1.00 155.22 ? 66  ASP A OD1 1 
ATOM   377   O  OD2 . ASP A 1 66  ? 211.049 203.438 321.867 1.00 155.22 ? 66  ASP A OD2 1 
ATOM   378   N  N   . MET A 1 67  ? 211.344 208.660 321.337 1.00 155.46 ? 67  MET A N   1 
ATOM   379   C  CA  . MET A 1 67  ? 210.299 209.616 320.991 1.00 155.46 ? 67  MET A CA  1 
ATOM   380   C  C   . MET A 1 67  ? 210.491 210.176 319.588 1.00 155.46 ? 67  MET A C   1 
ATOM   381   O  O   . MET A 1 67  ? 209.516 210.576 318.942 1.00 155.46 ? 67  MET A O   1 
ATOM   382   C  CB  . MET A 1 67  ? 210.270 210.751 322.013 1.00 155.46 ? 67  MET A CB  1 
ATOM   383   C  CG  . MET A 1 67  ? 211.523 211.607 322.009 1.00 155.46 ? 67  MET A CG  1 
ATOM   384   S  SD  . MET A 1 67  ? 211.494 212.922 323.240 1.00 155.46 ? 67  MET A SD  1 
ATOM   385   C  CE  . MET A 1 67  ? 213.066 213.712 322.906 1.00 155.46 ? 67  MET A CE  1 
ATOM   386   N  N   . LEU A 1 68  ? 211.731 210.217 319.102 1.00 158.20 ? 68  LEU A N   1 
ATOM   387   C  CA  . LEU A 1 68  ? 212.038 210.752 317.781 1.00 158.20 ? 68  LEU A CA  1 
ATOM   388   C  C   . LEU A 1 68  ? 211.956 209.704 316.678 1.00 158.20 ? 68  LEU A C   1 
ATOM   389   O  O   . LEU A 1 68  ? 212.011 210.064 315.497 1.00 158.20 ? 68  LEU A O   1 
ATOM   390   C  CB  . LEU A 1 68  ? 213.438 211.377 317.781 1.00 158.20 ? 68  LEU A CB  1 
ATOM   391   C  CG  . LEU A 1 68  ? 213.804 212.275 318.964 1.00 158.20 ? 68  LEU A CG  1 
ATOM   392   C  CD1 . LEU A 1 68  ? 215.237 212.771 318.837 1.00 158.20 ? 68  LEU A CD1 1 
ATOM   393   C  CD2 . LEU A 1 68  ? 212.840 213.442 319.074 1.00 158.20 ? 68  LEU A CD2 1 
ATOM   394   N  N   . ILE A 1 69  ? 211.827 208.429 317.029 1.00 158.84 ? 69  ILE A N   1 
ATOM   395   C  CA  . ILE A 1 69  ? 211.796 207.342 316.053 1.00 158.84 ? 69  ILE A CA  1 
ATOM   396   C  C   . ILE A 1 69  ? 210.383 207.216 315.493 1.00 158.84 ? 69  ILE A C   1 
ATOM   397   O  O   . ILE A 1 69  ? 209.410 207.451 316.223 1.00 158.84 ? 69  ILE A O   1 
ATOM   398   C  CB  . ILE A 1 69  ? 212.267 206.025 316.690 1.00 158.84 ? 69  ILE A CB  1 
ATOM   399   C  CG1 . ILE A 1 69  ? 213.614 206.225 317.388 1.00 158.84 ? 69  ILE A CG1 1 
ATOM   400   C  CG2 . ILE A 1 69  ? 212.375 204.922 315.654 1.00 158.84 ? 69  ILE A CG2 1 
ATOM   401   C  CD1 . ILE A 1 69  ? 214.724 206.669 316.460 1.00 158.84 ? 69  ILE A CD1 1 
ATOM   402   N  N   . PRO A 1 70  ? 210.218 206.881 314.213 1.00 154.68 ? 70  PRO A N   1 
ATOM   403   C  CA  . PRO A 1 70  ? 208.879 206.559 313.709 1.00 154.68 ? 70  PRO A CA  1 
ATOM   404   C  C   . PRO A 1 70  ? 208.285 205.376 314.457 1.00 154.68 ? 70  PRO A C   1 
ATOM   405   O  O   . PRO A 1 70  ? 208.994 204.467 314.894 1.00 154.68 ? 70  PRO A O   1 
ATOM   406   C  CB  . PRO A 1 70  ? 209.124 206.226 312.234 1.00 154.68 ? 70  PRO A CB  1 
ATOM   407   C  CG  . PRO A 1 70  ? 210.338 207.008 311.881 1.00 154.68 ? 70  PRO A CG  1 
ATOM   408   C  CD  . PRO A 1 70  ? 211.195 207.036 313.121 1.00 154.68 ? 70  PRO A CD  1 
ATOM   409   N  N   . ARG A 1 71  ? 206.958 205.398 314.595 1.00 150.29 ? 71  ARG A N   1 
ATOM   410   C  CA  . ARG A 1 71  ? 206.271 204.450 315.464 1.00 150.29 ? 71  ARG A CA  1 
ATOM   411   C  C   . ARG A 1 71  ? 206.467 203.004 315.033 1.00 150.29 ? 71  ARG A C   1 
ATOM   412   O  O   . ARG A 1 71  ? 206.273 202.095 315.846 1.00 150.29 ? 71  ARG A O   1 
ATOM   413   C  CB  . ARG A 1 71  ? 204.779 204.778 315.513 1.00 150.29 ? 71  ARG A CB  1 
ATOM   414   C  CG  . ARG A 1 71  ? 204.442 206.002 316.349 1.00 150.29 ? 71  ARG A CG  1 
ATOM   415   C  CD  . ARG A 1 71  ? 204.539 207.280 315.530 1.00 150.29 ? 71  ARG A CD  1 
ATOM   416   N  NE  . ARG A 1 71  ? 204.016 208.435 316.251 1.00 150.29 ? 71  ARG A NE  1 
ATOM   417   C  CZ  . ARG A 1 71  ? 204.757 209.265 316.971 1.00 150.29 ? 71  ARG A CZ  1 
ATOM   418   N  NH1 . ARG A 1 71  ? 206.065 209.102 317.087 1.00 150.29 ? 71  ARG A NH1 1 
ATOM   419   N  NH2 . ARG A 1 71  ? 204.171 210.286 317.590 1.00 150.29 ? 71  ARG A NH2 1 
ATOM   420   N  N   . ASP A 1 72  ? 206.851 202.768 313.779 1.00 146.72 ? 72  ASP A N   1 
ATOM   421   C  CA  . ASP A 1 72  ? 207.008 201.403 313.297 1.00 146.72 ? 72  ASP A CA  1 
ATOM   422   C  C   . ASP A 1 72  ? 208.195 200.689 313.931 1.00 146.72 ? 72  ASP A C   1 
ATOM   423   O  O   . ASP A 1 72  ? 208.262 199.457 313.878 1.00 146.72 ? 72  ASP A O   1 
ATOM   424   C  CB  . ASP A 1 72  ? 207.147 201.410 311.776 1.00 146.72 ? 72  ASP A CB  1 
ATOM   425   C  CG  . ASP A 1 72  ? 206.047 202.200 311.101 1.00 146.72 ? 72  ASP A CG  1 
ATOM   426   O  OD1 . ASP A 1 72  ? 205.006 202.438 311.749 1.00 146.72 ? 72  ASP A OD1 1 
ATOM   427   O  OD2 . ASP A 1 72  ? 206.221 202.585 309.926 1.00 146.72 ? 72  ASP A OD2 1 
ATOM   428   N  N   . LEU A 1 73  ? 209.131 201.426 314.521 1.00 148.18 ? 73  LEU A N   1 
ATOM   429   C  CA  . LEU A 1 73  ? 210.283 200.825 315.178 1.00 148.18 ? 73  LEU A CA  1 
ATOM   430   C  C   . LEU A 1 73  ? 210.169 200.822 316.696 1.00 148.18 ? 73  LEU A C   1 
ATOM   431   O  O   . LEU A 1 73  ? 211.162 200.543 317.373 1.00 148.18 ? 73  LEU A O   1 
ATOM   432   C  CB  . LEU A 1 73  ? 211.566 201.551 314.763 1.00 148.18 ? 73  LEU A CB  1 
ATOM   433   C  CG  . LEU A 1 73  ? 212.301 201.009 313.535 1.00 148.18 ? 73  LEU A CG  1 
ATOM   434   C  CD1 . LEU A 1 73  ? 211.586 201.409 312.252 1.00 148.18 ? 73  LEU A CD1 1 
ATOM   435   C  CD2 . LEU A 1 73  ? 213.744 201.488 313.521 1.00 148.18 ? 73  LEU A CD2 1 
ATOM   436   N  N   . ARG A 1 74  ? 208.994 201.127 317.241 1.00 154.72 ? 74  ARG A N   1 
ATOM   437   C  CA  . ARG A 1 74  ? 208.819 201.160 318.693 1.00 154.72 ? 74  ARG A CA  1 
ATOM   438   C  C   . ARG A 1 74  ? 209.148 199.838 319.378 1.00 154.72 ? 74  ARG A C   1 
ATOM   439   O  O   . ARG A 1 74  ? 209.905 199.856 320.362 1.00 154.72 ? 74  ARG A O   1 
ATOM   440   C  CB  . ARG A 1 74  ? 207.387 201.601 319.027 1.00 154.72 ? 74  ARG A CB  1 
ATOM   441   C  CG  . ARG A 1 74  ? 207.114 203.072 318.810 1.00 154.72 ? 74  ARG A CG  1 
ATOM   442   C  CD  . ARG A 1 74  ? 207.813 203.918 319.857 1.00 154.72 ? 74  ARG A CD  1 
ATOM   443   N  NE  . ARG A 1 74  ? 207.703 205.339 319.558 1.00 154.72 ? 74  ARG A NE  1 
ATOM   444   C  CZ  . ARG A 1 74  ? 208.351 205.949 318.575 1.00 154.72 ? 74  ARG A CZ  1 
ATOM   445   N  NH1 . ARG A 1 74  ? 209.183 205.291 317.784 1.00 154.72 ? 74  ARG A NH1 1 
ATOM   446   N  NH2 . ARG A 1 74  ? 208.170 207.253 318.389 1.00 154.72 ? 74  ARG A NH2 1 
ATOM   447   N  N   . PRO A 1 75  ? 208.639 198.679 318.938 1.00 159.68 ? 75  PRO A N   1 
ATOM   448   C  CA  . PRO A 1 75  ? 208.976 197.431 319.639 1.00 159.68 ? 75  PRO A CA  1 
ATOM   449   C  C   . PRO A 1 75  ? 210.298 196.825 319.206 1.00 159.68 ? 75  PRO A C   1 
ATOM   450   O  O   . PRO A 1 75  ? 210.628 195.723 319.663 1.00 159.68 ? 75  PRO A O   1 
ATOM   451   C  CB  . PRO A 1 75  ? 207.805 196.497 319.287 1.00 159.68 ? 75  PRO A CB  1 
ATOM   452   C  CG  . PRO A 1 75  ? 206.822 197.342 318.496 1.00 159.68 ? 75  PRO A CG  1 
ATOM   453   C  CD  . PRO A 1 75  ? 207.641 198.426 317.888 1.00 159.68 ? 75  PRO A CD  1 
ATOM   454   N  N   . ALA A 1 76  ? 211.063 197.499 318.347 1.00 155.77 ? 76  ALA A N   1 
ATOM   455   C  CA  . ALA A 1 76  ? 212.266 196.912 317.776 1.00 155.77 ? 76  ALA A CA  1 
ATOM   456   C  C   . ALA A 1 76  ? 213.521 197.753 317.934 1.00 155.77 ? 76  ALA A C   1 
ATOM   457   O  O   . ALA A 1 76  ? 214.614 197.177 317.980 1.00 155.77 ? 76  ALA A O   1 
ATOM   458   C  CB  . ALA A 1 76  ? 212.057 196.624 316.283 1.00 155.77 ? 76  ALA A CB  1 
ATOM   459   N  N   . HIS A 1 77  ? 213.342 199.066 318.027 1.00 157.53 ? 77  HIS A N   1 
ATOM   460   C  CA  . HIS A 1 77  ? 214.503 199.991 318.101 1.00 157.53 ? 77  HIS A CA  1 
ATOM   461   C  C   . HIS A 1 77  ? 215.383 199.583 319.288 1.00 157.53 ? 77  HIS A C   1 
ATOM   462   O  O   . HIS A 1 77  ? 216.543 199.174 319.072 1.00 157.53 ? 77  HIS A O   1 
ATOM   463   C  CB  . HIS A 1 77  ? 214.030 201.450 318.149 1.00 157.53 ? 77  HIS A CB  1 
ATOM   464   C  CG  . HIS A 1 77  ? 215.145 202.439 318.057 1.00 157.53 ? 77  HIS A CG  1 
ATOM   465   N  ND1 . HIS A 1 77  ? 215.925 202.798 319.134 1.00 157.53 ? 77  HIS A ND1 1 
ATOM   466   C  CD2 . HIS A 1 77  ? 215.613 203.135 317.013 1.00 157.53 ? 77  HIS A CD2 1 
ATOM   467   C  CE1 . HIS A 1 77  ? 216.828 203.685 318.743 1.00 157.53 ? 77  HIS A CE1 1 
ATOM   468   N  NE2 . HIS A 1 77  ? 216.656 203.905 317.458 1.00 157.53 ? 77  HIS A NE2 1 
ATOM   469   N  N   . PRO A 1 78  ? 214.902 199.646 320.547 1.00 157.65 ? 78  PRO A N   1 
ATOM   470   C  CA  . PRO A 1 78  ? 215.717 199.184 321.684 1.00 157.65 ? 78  PRO A CA  1 
ATOM   471   C  C   . PRO A 1 78  ? 216.161 197.740 321.534 1.00 157.65 ? 78  PRO A C   1 
ATOM   472   O  O   . PRO A 1 78  ? 217.278 197.388 321.935 1.00 157.65 ? 78  PRO A O   1 
ATOM   473   C  CB  . PRO A 1 78  ? 214.785 199.377 322.889 1.00 157.65 ? 78  PRO A CB  1 
ATOM   474   C  CG  . PRO A 1 78  ? 213.778 200.376 322.441 1.00 157.65 ? 78  PRO A CG  1 
ATOM   475   C  CD  . PRO A 1 78  ? 213.571 200.099 320.988 1.00 157.65 ? 78  PRO A CD  1 
ATOM   476   N  N   . GLU A 1 79  ? 215.308 196.891 320.955 1.00 162.69 ? 79  GLU A N   1 
ATOM   477   C  CA  . GLU A 1 79  ? 215.709 195.520 320.669 1.00 162.69 ? 79  GLU A CA  1 
ATOM   478   C  C   . GLU A 1 79  ? 216.853 195.480 319.667 1.00 162.69 ? 79  GLU A C   1 
ATOM   479   O  O   . GLU A 1 79  ? 217.763 194.655 319.796 1.00 162.69 ? 79  GLU A O   1 
ATOM   480   C  CB  . GLU A 1 79  ? 214.515 194.717 320.150 1.00 162.69 ? 79  GLU A CB  1 
ATOM   481   C  CG  . GLU A 1 79  ? 214.809 193.245 319.897 1.00 162.69 ? 79  GLU A CG  1 
ATOM   482   C  CD  . GLU A 1 79  ? 215.157 192.488 321.165 1.00 162.69 ? 79  GLU A CD  1 
ATOM   483   O  OE1 . GLU A 1 79  ? 214.678 192.882 322.249 1.00 162.69 ? 79  GLU A OE1 1 
ATOM   484   O  OE2 . GLU A 1 79  ? 215.909 191.495 321.076 1.00 162.69 ? 79  GLU A OE2 1 
ATOM   485   N  N   . TYR A 1 80  ? 216.825 196.361 318.666 1.00 158.36 ? 80  TYR A N   1 
ATOM   486   C  CA  . TYR A 1 80  ? 217.943 196.452 317.734 1.00 158.36 ? 80  TYR A CA  1 
ATOM   487   C  C   . TYR A 1 80  ? 219.217 196.894 318.443 1.00 158.36 ? 80  TYR A C   1 
ATOM   488   O  O   . TYR A 1 80  ? 220.304 196.381 318.154 1.00 158.36 ? 80  TYR A O   1 
ATOM   489   C  CB  . TYR A 1 80  ? 217.599 197.409 316.596 1.00 158.36 ? 80  TYR A CB  1 
ATOM   490   C  CG  . TYR A 1 80  ? 216.499 196.905 315.696 1.00 158.36 ? 80  TYR A CG  1 
ATOM   491   C  CD1 . TYR A 1 80  ? 216.245 195.545 315.577 1.00 158.36 ? 80  TYR A CD1 1 
ATOM   492   C  CD2 . TYR A 1 80  ? 215.718 197.786 314.962 1.00 158.36 ? 80  TYR A CD2 1 
ATOM   493   C  CE1 . TYR A 1 80  ? 215.240 195.078 314.754 1.00 158.36 ? 80  TYR A CE1 1 
ATOM   494   C  CE2 . TYR A 1 80  ? 214.712 197.328 314.134 1.00 158.36 ? 80  TYR A CE2 1 
ATOM   495   C  CZ  . TYR A 1 80  ? 214.478 195.973 314.033 1.00 158.36 ? 80  TYR A CZ  1 
ATOM   496   O  OH  . TYR A 1 80  ? 213.475 195.511 313.212 1.00 158.36 ? 80  TYR A OH  1 
ATOM   497   N  N   . ILE A 1 81  ? 219.102 197.849 319.368 1.00 156.49 ? 81  ILE A N   1 
ATOM   498   C  CA  . ILE A 1 81  ? 220.267 198.296 320.127 1.00 156.49 ? 81  ILE A CA  1 
ATOM   499   C  C   . ILE A 1 81  ? 220.852 197.136 320.922 1.00 156.49 ? 81  ILE A C   1 
ATOM   500   O  O   . ILE A 1 81  ? 222.069 196.915 320.937 1.00 156.49 ? 81  ILE A O   1 
ATOM   501   C  CB  . ILE A 1 81  ? 219.889 199.470 321.048 1.00 156.49 ? 81  ILE A CB  1 
ATOM   502   C  CG1 . ILE A 1 81  ? 219.649 200.739 320.230 1.00 156.49 ? 81  ILE A CG1 1 
ATOM   503   C  CG2 . ILE A 1 81  ? 220.969 199.699 322.094 1.00 156.49 ? 81  ILE A CG2 1 
ATOM   504   C  CD1 . ILE A 1 81  ? 218.996 201.850 321.020 1.00 156.49 ? 81  ILE A CD1 1 
ATOM   505   N  N   . ARG A 1 82  ? 219.984 196.376 321.591 1.00 161.00 ? 82  ARG A N   1 
ATOM   506   C  CA  . ARG A 1 82  ? 220.440 195.232 322.373 1.00 161.00 ? 82  ARG A CA  1 
ATOM   507   C  C   . ARG A 1 82  ? 221.086 194.176 321.484 1.00 161.00 ? 82  ARG A C   1 
ATOM   508   O  O   . ARG A 1 82  ? 222.114 193.593 321.847 1.00 161.00 ? 82  ARG A O   1 
ATOM   509   C  CB  . ARG A 1 82  ? 219.272 194.635 323.159 1.00 161.00 ? 82  ARG A CB  1 
ATOM   510   C  CG  . ARG A 1 82  ? 219.616 193.379 323.947 1.00 161.00 ? 82  ARG A CG  1 
ATOM   511   C  CD  . ARG A 1 82  ? 219.066 192.129 323.274 1.00 161.00 ? 82  ARG A CD  1 
ATOM   512   N  NE  . ARG A 1 82  ? 219.233 190.941 324.103 1.00 161.00 ? 82  ARG A NE  1 
ATOM   513   C  CZ  . ARG A 1 82  ? 218.963 189.706 323.704 1.00 161.00 ? 82  ARG A CZ  1 
ATOM   514   N  NH1 . ARG A 1 82  ? 218.507 189.457 322.487 1.00 161.00 ? 82  ARG A NH1 1 
ATOM   515   N  NH2 . ARG A 1 82  ? 219.155 188.695 324.547 1.00 161.00 ? 82  ARG A NH2 1 
ATOM   516   N  N   . HIS A 1 83  ? 220.493 193.910 320.318 1.00 160.38 ? 83  HIS A N   1 
ATOM   517   C  CA  . HIS A 1 83  ? 221.051 192.913 319.411 1.00 160.38 ? 83  HIS A CA  1 
ATOM   518   C  C   . HIS A 1 83  ? 222.425 193.337 318.911 1.00 160.38 ? 83  HIS A C   1 
ATOM   519   O  O   . HIS A 1 83  ? 223.354 192.523 318.849 1.00 160.38 ? 83  HIS A O   1 
ATOM   520   C  CB  . HIS A 1 83  ? 220.098 192.679 318.238 1.00 160.38 ? 83  HIS A CB  1 
ATOM   521   C  CG  . HIS A 1 83  ? 220.572 191.637 317.274 1.00 160.38 ? 83  HIS A CG  1 
ATOM   522   N  ND1 . HIS A 1 83  ? 221.417 191.924 316.224 1.00 160.38 ? 83  HIS A ND1 1 
ATOM   523   C  CD2 . HIS A 1 83  ? 220.320 190.309 317.202 1.00 160.38 ? 83  HIS A CD2 1 
ATOM   524   C  CE1 . HIS A 1 83  ? 221.665 190.818 315.545 1.00 160.38 ? 83  HIS A CE1 1 
ATOM   525   N  NE2 . HIS A 1 83  ? 221.011 189.823 316.118 1.00 160.38 ? 83  HIS A NE2 1 
ATOM   526   N  N   . ASN A 1 84  ? 222.572 194.612 318.548 1.00 155.88 ? 84  ASN A N   1 
ATOM   527   C  CA  . ASN A 1 84  ? 223.871 195.104 318.103 1.00 155.88 ? 84  ASN A CA  1 
ATOM   528   C  C   . ASN A 1 84  ? 224.899 195.023 319.223 1.00 155.88 ? 84  ASN A C   1 
ATOM   529   O  O   . ASN A 1 84  ? 226.047 194.621 318.997 1.00 155.88 ? 84  ASN A O   1 
ATOM   530   C  CB  . ASN A 1 84  ? 223.742 196.539 317.592 1.00 155.88 ? 84  ASN A CB  1 
ATOM   531   C  CG  . ASN A 1 84  ? 224.945 196.980 316.779 1.00 155.88 ? 84  ASN A CG  1 
ATOM   532   O  OD1 . ASN A 1 84  ? 225.886 196.213 316.573 1.00 155.88 ? 84  ASN A OD1 1 
ATOM   533   N  ND2 . ASN A 1 84  ? 224.919 198.223 316.311 1.00 155.88 ? 84  ASN A ND2 1 
ATOM   534   N  N   . ARG A 1 85  ? 224.501 195.396 320.442 1.00 159.45 ? 85  ARG A N   1 
ATOM   535   C  CA  . ARG A 1 85  ? 225.423 195.342 321.571 1.00 159.45 ? 85  ARG A CA  1 
ATOM   536   C  C   . ARG A 1 85  ? 225.867 193.913 321.859 1.00 159.45 ? 85  ARG A C   1 
ATOM   537   O  O   . ARG A 1 85  ? 227.049 193.664 322.126 1.00 159.45 ? 85  ARG A O   1 
ATOM   538   C  CB  . ARG A 1 85  ? 224.768 195.962 322.803 1.00 159.45 ? 85  ARG A CB  1 
ATOM   539   C  CG  . ARG A 1 85  ? 225.726 196.226 323.943 1.00 159.45 ? 85  ARG A CG  1 
ATOM   540   C  CD  . ARG A 1 85  ? 225.186 197.299 324.866 1.00 159.45 ? 85  ARG A CD  1 
ATOM   541   N  NE  . ARG A 1 85  ? 225.177 198.608 324.225 1.00 159.45 ? 85  ARG A NE  1 
ATOM   542   C  CZ  . ARG A 1 85  ? 225.818 199.669 324.694 1.00 159.45 ? 85  ARG A CZ  1 
ATOM   543   N  NH1 . ARG A 1 85  ? 226.539 199.606 325.800 1.00 159.45 ? 85  ARG A NH1 1 
ATOM   544   N  NH2 . ARG A 1 85  ? 225.738 200.820 324.034 1.00 159.45 ? 85  ARG A NH2 1 
ATOM   545   N  N   . GLU A 1 86  ? 224.935 192.959 321.812 1.00 159.36 ? 86  GLU A N   1 
ATOM   546   C  CA  . GLU A 1 86  ? 225.277 191.558 322.025 1.00 159.36 ? 86  GLU A CA  1 
ATOM   547   C  C   . GLU A 1 86  ? 226.140 190.989 320.908 1.00 159.36 ? 86  GLU A C   1 
ATOM   548   O  O   . GLU A 1 86  ? 227.040 190.189 321.186 1.00 159.36 ? 86  GLU A O   1 
ATOM   549   C  CB  . GLU A 1 86  ? 224.006 190.719 322.176 1.00 159.36 ? 86  GLU A CB  1 
ATOM   550   C  CG  . GLU A 1 86  ? 223.219 191.010 323.444 1.00 159.36 ? 86  GLU A CG  1 
ATOM   551   C  CD  . GLU A 1 86  ? 222.550 189.774 324.013 1.00 159.36 ? 86  GLU A CD  1 
ATOM   552   O  OE1 . GLU A 1 86  ? 222.112 188.914 323.220 1.00 159.36 ? 86  GLU A OE1 1 
ATOM   553   O  OE2 . GLU A 1 86  ? 222.463 189.662 325.254 1.00 159.36 ? 86  GLU A OE2 1 
ATOM   554   N  N   . GLY A 1 87  ? 225.890 191.378 319.654 1.00 158.13 ? 87  GLY A N   1 
ATOM   555   C  CA  . GLY A 1 87  ? 226.732 190.932 318.560 1.00 158.13 ? 87  GLY A CA  1 
ATOM   556   C  C   . GLY A 1 87  ? 228.111 191.551 318.547 1.00 158.13 ? 87  GLY A C   1 
ATOM   557   O  O   . GLY A 1 87  ? 229.041 190.951 317.998 1.00 158.13 ? 87  GLY A O   1 
ATOM   558   N  N   . GLY A 1 88  ? 228.265 192.732 319.140 1.00 155.51 ? 88  GLY A N   1 
ATOM   559   C  CA  . GLY A 1 88  ? 229.573 193.349 319.252 1.00 155.51 ? 88  GLY A CA  1 
ATOM   560   C  C   . GLY A 1 88  ? 230.218 193.722 317.937 1.00 155.51 ? 88  GLY A C   1 
ATOM   561   O  O   . GLY A 1 88  ? 231.400 193.428 317.730 1.00 155.51 ? 88  GLY A O   1 
ATOM   562   N  N   . LYS A 1 89  ? 229.472 194.358 317.034 1.00 149.48 ? 89  LYS A N   1 
ATOM   563   C  CA  . LYS A 1 89  ? 230.025 194.779 315.753 1.00 149.48 ? 89  LYS A CA  1 
ATOM   564   C  C   . LYS A 1 89  ? 231.083 195.856 315.956 1.00 149.48 ? 89  LYS A C   1 
ATOM   565   O  O   . LYS A 1 89  ? 230.759 196.999 316.293 1.00 149.48 ? 89  LYS A O   1 
ATOM   566   C  CB  . LYS A 1 89  ? 228.915 195.287 314.830 1.00 149.48 ? 89  LYS A CB  1 
ATOM   567   C  CG  . LYS A 1 89  ? 227.887 194.231 314.456 1.00 149.48 ? 89  LYS A CG  1 
ATOM   568   C  CD  . LYS A 1 89  ? 226.974 194.718 313.344 1.00 149.48 ? 89  LYS A CD  1 
ATOM   569   C  CE  . LYS A 1 89  ? 225.860 193.721 313.067 1.00 149.48 ? 89  LYS A CE  1 
ATOM   570   N  NZ  . LYS A 1 89  ? 225.047 194.112 311.882 1.00 149.48 ? 89  LYS A NZ  1 
ATOM   571   N  N   . ALA A 1 90  ? 232.353 195.494 315.758 1.00 148.82 ? 90  ALA A N   1 
ATOM   572   C  CA  . ALA A 1 90  ? 233.445 196.441 315.953 1.00 148.82 ? 90  ALA A CA  1 
ATOM   573   C  C   . ALA A 1 90  ? 233.400 197.591 314.955 1.00 148.82 ? 90  ALA A C   1 
ATOM   574   O  O   . ALA A 1 90  ? 233.666 198.739 315.329 1.00 148.82 ? 90  ALA A O   1 
ATOM   575   C  CB  . ALA A 1 90  ? 234.790 195.720 315.858 1.00 148.82 ? 90  ALA A CB  1 
ATOM   576   N  N   . ARG A 1 91  ? 233.071 197.311 313.698 1.00 145.98 ? 91  ARG A N   1 
ATOM   577   C  CA  . ARG A 1 91  ? 233.028 198.319 312.648 1.00 145.98 ? 91  ARG A CA  1 
ATOM   578   C  C   . ARG A 1 91  ? 231.578 198.634 312.306 1.00 145.98 ? 91  ARG A C   1 
ATOM   579   O  O   . ARG A 1 91  ? 230.776 197.721 312.084 1.00 145.98 ? 91  ARG A O   1 
ATOM   580   C  CB  . ARG A 1 91  ? 233.777 197.844 311.401 1.00 145.98 ? 91  ARG A CB  1 
ATOM   581   C  CG  . ARG A 1 91  ? 233.751 198.832 310.246 1.00 145.98 ? 91  ARG A CG  1 
ATOM   582   C  CD  . ARG A 1 91  ? 234.381 200.158 310.641 1.00 145.98 ? 91  ARG A CD  1 
ATOM   583   N  NE  . ARG A 1 91  ? 233.420 201.254 310.596 1.00 145.98 ? 91  ARG A NE  1 
ATOM   584   C  CZ  . ARG A 1 91  ? 233.639 202.464 311.093 1.00 145.98 ? 91  ARG A CZ  1 
ATOM   585   N  NH1 . ARG A 1 91  ? 234.781 202.772 311.686 1.00 145.98 ? 91  ARG A NH1 1 
ATOM   586   N  NH2 . ARG A 1 91  ? 232.687 203.388 310.993 1.00 145.98 ? 91  ARG A NH2 1 
ATOM   587   N  N   . VAL A 1 92  ? 231.250 199.921 312.266 1.00 143.66 ? 92  VAL A N   1 
ATOM   588   C  CA  . VAL A 1 92  ? 229.896 200.374 311.972 1.00 143.66 ? 92  VAL A CA  1 
ATOM   589   C  C   . VAL A 1 92  ? 229.718 200.463 310.463 1.00 143.66 ? 92  VAL A C   1 
ATOM   590   O  O   . VAL A 1 92  ? 230.492 201.139 309.774 1.00 143.66 ? 92  VAL A O   1 
ATOM   591   C  CB  . VAL A 1 92  ? 229.614 201.730 312.638 1.00 143.66 ? 92  VAL A CB  1 
ATOM   592   C  CG1 . VAL A 1 92  ? 228.324 202.314 312.104 1.00 143.66 ? 92  VAL A CG1 1 
ATOM   593   C  CG2 . VAL A 1 92  ? 229.552 201.576 314.150 1.00 143.66 ? 92  VAL A CG2 1 
ATOM   594   N  N   . GLU A 1 93  ? 228.696 199.779 309.946 1.00 140.90 ? 93  GLU A N   1 
ATOM   595   C  CA  . GLU A 1 93  ? 228.412 199.797 308.518 1.00 140.90 ? 93  GLU A CA  1 
ATOM   596   C  C   . GLU A 1 93  ? 226.930 199.928 308.192 1.00 140.90 ? 93  GLU A C   1 
ATOM   597   O  O   . GLU A 1 93  ? 226.565 199.781 307.022 1.00 140.90 ? 93  GLU A O   1 
ATOM   598   C  CB  . GLU A 1 93  ? 228.963 198.529 307.844 1.00 140.90 ? 93  GLU A CB  1 
ATOM   599   C  CG  . GLU A 1 93  ? 230.479 198.406 307.877 1.00 140.90 ? 93  GLU A CG  1 
ATOM   600   C  CD  . GLU A 1 93  ? 230.984 197.214 307.088 1.00 140.90 ? 93  GLU A CD  1 
ATOM   601   O  OE1 . GLU A 1 93  ? 230.266 196.194 307.024 1.00 140.90 ? 93  GLU A OE1 1 
ATOM   602   O  OE2 . GLU A 1 93  ? 232.099 197.297 306.532 1.00 140.90 ? 93  GLU A OE2 1 
ATOM   603   N  N   . GLY A 1 94  ? 226.068 200.197 309.175 1.00 137.10 ? 94  GLY A N   1 
ATOM   604   C  CA  . GLY A 1 94  ? 224.643 200.274 308.939 1.00 137.10 ? 94  GLY A CA  1 
ATOM   605   C  C   . GLY A 1 94  ? 224.162 201.685 308.643 1.00 137.10 ? 94  GLY A C   1 
ATOM   606   O  O   . GLY A 1 94  ? 224.930 202.646 308.605 1.00 137.10 ? 94  GLY A O   1 
ATOM   607   N  N   . MET A 1 95  ? 222.849 201.790 308.428 1.00 133.70 ? 95  MET A N   1 
ATOM   608   C  CA  . MET A 1 95  ? 222.171 203.062 308.163 1.00 133.70 ? 95  MET A CA  1 
ATOM   609   C  C   . MET A 1 95  ? 222.731 203.770 306.933 1.00 133.70 ? 95  MET A C   1 
ATOM   610   O  O   . MET A 1 95  ? 222.766 205.002 306.875 1.00 133.70 ? 95  MET A O   1 
ATOM   611   C  CB  . MET A 1 95  ? 222.227 203.991 309.379 1.00 133.70 ? 95  MET A CB  1 
ATOM   612   C  CG  . MET A 1 95  ? 221.342 203.555 310.530 1.00 133.70 ? 95  MET A CG  1 
ATOM   613   S  SD  . MET A 1 95  ? 221.887 204.213 312.115 1.00 133.70 ? 95  MET A SD  1 
ATOM   614   C  CE  . MET A 1 95  ? 222.221 205.919 311.700 1.00 133.70 ? 95  MET A CE  1 
ATOM   615   N  N   . SER A 1 96  ? 223.177 203.001 305.938 1.00 123.82 ? 96  SER A N   1 
ATOM   616   C  CA  . SER A 1 96  ? 223.653 203.613 304.703 1.00 123.82 ? 96  SER A CA  1 
ATOM   617   C  C   . SER A 1 96  ? 222.500 204.089 303.832 1.00 123.82 ? 96  SER A C   1 
ATOM   618   O  O   . SER A 1 96  ? 222.587 205.158 303.220 1.00 123.82 ? 96  SER A O   1 
ATOM   619   C  CB  . SER A 1 96  ? 224.526 202.627 303.929 1.00 123.82 ? 96  SER A CB  1 
ATOM   620   O  OG  . SER A 1 96  ? 223.793 201.466 303.580 1.00 123.82 ? 96  SER A OG  1 
ATOM   621   N  N   . ALA A 1 97  ? 221.417 203.321 303.771 1.00 113.92 ? 97  ALA A N   1 
ATOM   622   C  CA  . ALA A 1 97  ? 220.314 203.650 302.881 1.00 113.92 ? 97  ALA A CA  1 
ATOM   623   C  C   . ALA A 1 97  ? 219.593 204.905 303.349 1.00 113.92 ? 97  ALA A C   1 
ATOM   624   O  O   . ALA A 1 97  ? 219.381 205.111 304.547 1.00 113.92 ? 97  ALA A O   1 
ATOM   625   C  CB  . ALA A 1 97  ? 219.331 202.484 302.799 1.00 113.92 ? 97  ALA A CB  1 
ATOM   626   N  N   . GLU A 1 98  ? 219.220 205.747 302.390 1.00 108.96 ? 98  GLU A N   1 
ATOM   627   C  CA  . GLU A 1 98  ? 218.432 206.931 302.698 1.00 108.96 ? 98  GLU A CA  1 
ATOM   628   C  C   . GLU A 1 98  ? 217.069 206.515 303.231 1.00 108.96 ? 98  GLU A C   1 
ATOM   629   O  O   . GLU A 1 98  ? 216.492 205.520 302.785 1.00 108.96 ? 98  GLU A O   1 
ATOM   630   C  CB  . GLU A 1 98  ? 218.282 207.798 301.449 1.00 108.96 ? 98  GLU A CB  1 
ATOM   631   C  CG  . GLU A 1 98  ? 219.611 208.174 300.808 1.00 108.96 ? 98  GLU A CG  1 
ATOM   632   C  CD  . GLU A 1 98  ? 219.472 208.576 299.354 1.00 108.96 ? 98  GLU A CD  1 
ATOM   633   O  OE1 . GLU A 1 98  ? 219.206 207.689 298.515 1.00 108.96 ? 98  GLU A OE1 1 
ATOM   634   O  OE2 . GLU A 1 98  ? 219.623 209.777 299.048 1.00 108.96 ? 98  GLU A OE2 1 
ATOM   635   N  N   . LEU A 1 99  ? 216.556 207.272 304.203 1.00 115.01 ? 99  LEU A N   1 
ATOM   636   C  CA  . LEU A 1 99  ? 215.325 206.899 304.886 1.00 115.01 ? 99  LEU A CA  1 
ATOM   637   C  C   . LEU A 1 99  ? 214.359 208.072 304.945 1.00 115.01 ? 99  LEU A C   1 
ATOM   638   O  O   . LEU A 1 99  ? 214.767 209.220 305.146 1.00 115.01 ? 99  LEU A O   1 
ATOM   639   C  CB  . LEU A 1 99  ? 215.606 206.398 306.305 1.00 115.01 ? 99  LEU A CB  1 
ATOM   640   C  CG  . LEU A 1 99  ? 215.969 204.918 306.405 1.00 115.01 ? 99  LEU A CG  1 
ATOM   641   C  CD1 . LEU A 1 99  ? 216.661 204.618 307.724 1.00 115.01 ? 99  LEU A CD1 1 
ATOM   642   C  CD2 . LEU A 1 99  ? 214.719 204.069 306.243 1.00 115.01 ? 99  LEU A CD2 1 
ATOM   643   N  N   . GLN A 1 100 ? 213.078 207.773 304.769 1.00 118.43 ? 100 GLN A N   1 
ATOM   644   C  CA  . GLN A 1 100 ? 212.049 208.777 304.970 1.00 118.43 ? 100 GLN A CA  1 
ATOM   645   C  C   . GLN A 1 100 ? 211.925 209.098 306.453 1.00 118.43 ? 100 GLN A C   1 
ATOM   646   O  O   . GLN A 1 100 ? 212.274 208.291 307.318 1.00 118.43 ? 100 GLN A O   1 
ATOM   647   C  CB  . GLN A 1 100 ? 210.712 208.294 304.413 1.00 118.43 ? 100 GLN A CB  1 
ATOM   648   C  CG  . GLN A 1 100 ? 210.191 207.011 305.047 1.00 118.43 ? 100 GLN A CG  1 
ATOM   649   C  CD  . GLN A 1 100 ? 209.308 207.267 306.254 1.00 118.43 ? 100 GLN A CD  1 
ATOM   650   O  OE1 . GLN A 1 100 ? 208.638 208.296 306.340 1.00 118.43 ? 100 GLN A OE1 1 
ATOM   651   N  NE2 . GLN A 1 100 ? 209.305 206.329 307.194 1.00 118.43 ? 100 GLN A NE2 1 
ATOM   652   N  N   . LEU A 1 101 ? 211.438 210.299 306.744 1.00 125.87 ? 101 LEU A N   1 
ATOM   653   C  CA  . LEU A 1 101 ? 211.289 210.752 308.115 1.00 125.87 ? 101 LEU A CA  1 
ATOM   654   C  C   . LEU A 1 101 ? 210.006 211.559 308.240 1.00 125.87 ? 101 LEU A C   1 
ATOM   655   O  O   . LEU A 1 101 ? 209.565 212.204 307.285 1.00 125.87 ? 101 LEU A O   1 
ATOM   656   C  CB  . LEU A 1 101 ? 212.499 211.590 308.559 1.00 125.87 ? 101 LEU A CB  1 
ATOM   657   C  CG  . LEU A 1 101 ? 212.565 212.055 310.016 1.00 125.87 ? 101 LEU A CG  1 
ATOM   658   C  CD1 . LEU A 1 101 ? 213.961 211.842 310.581 1.00 125.87 ? 101 LEU A CD1 1 
ATOM   659   C  CD2 . LEU A 1 101 ? 212.154 213.515 310.139 1.00 125.87 ? 101 LEU A CD2 1 
ATOM   660   N  N   . GLU A 1 102 ? 209.407 211.507 309.426 1.00 135.37 ? 102 GLU A N   1 
ATOM   661   C  CA  . GLU A 1 102 ? 208.231 212.296 309.759 1.00 135.37 ? 102 GLU A CA  1 
ATOM   662   C  C   . GLU A 1 102 ? 208.581 213.238 310.901 1.00 135.37 ? 102 GLU A C   1 
ATOM   663   O  O   . GLU A 1 102 ? 209.087 212.799 311.939 1.00 135.37 ? 102 GLU A O   1 
ATOM   664   C  CB  . GLU A 1 102 ? 207.052 211.400 310.147 1.00 135.37 ? 102 GLU A CB  1 
ATOM   665   C  CG  . GLU A 1 102 ? 205.769 212.157 310.440 1.00 135.37 ? 102 GLU A CG  1 
ATOM   666   C  CD  . GLU A 1 102 ? 204.633 211.239 310.844 1.00 135.37 ? 102 GLU A CD  1 
ATOM   667   O  OE1 . GLU A 1 102 ? 204.467 210.180 310.204 1.00 135.37 ? 102 GLU A OE1 1 
ATOM   668   O  OE2 . GLU A 1 102 ? 203.907 211.577 311.802 1.00 135.37 ? 102 GLU A OE2 1 
ATOM   669   N  N   . LYS A 1 103 ? 208.312 214.526 310.708 1.00 137.44 ? 103 LYS A N   1 
ATOM   670   C  CA  . LYS A 1 103 ? 208.652 215.529 311.705 1.00 137.44 ? 103 LYS A CA  1 
ATOM   671   C  C   . LYS A 1 103 ? 207.622 215.528 312.833 1.00 137.44 ? 103 LYS A C   1 
ATOM   672   O  O   . LYS A 1 103 ? 206.657 214.758 312.836 1.00 137.44 ? 103 LYS A O   1 
ATOM   673   C  CB  . LYS A 1 103 ? 208.757 216.907 311.057 1.00 137.44 ? 103 LYS A CB  1 
ATOM   674   C  CG  . LYS A 1 103 ? 209.887 217.037 310.049 1.00 137.44 ? 103 LYS A CG  1 
ATOM   675   C  CD  . LYS A 1 103 ? 210.306 218.489 309.879 1.00 137.44 ? 103 LYS A CD  1 
ATOM   676   C  CE  . LYS A 1 103 ? 211.330 218.643 308.766 1.00 137.44 ? 103 LYS A CE  1 
ATOM   677   N  NZ  . LYS A 1 103 ? 211.878 220.026 308.705 1.00 137.44 ? 103 LYS A NZ  1 
ATOM   678   N  N   . LYS A 1 104 ? 207.838 216.408 313.815 1.00 141.19 ? 104 LYS A N   1 
ATOM   679   C  CA  . LYS A 1 104 ? 206.920 216.501 314.945 1.00 141.19 ? 104 LYS A CA  1 
ATOM   680   C  C   . LYS A 1 104 ? 205.543 216.987 314.512 1.00 141.19 ? 104 LYS A C   1 
ATOM   681   O  O   . LYS A 1 104 ? 204.529 216.547 315.065 1.00 141.19 ? 104 LYS A O   1 
ATOM   682   C  CB  . LYS A 1 104 ? 207.499 217.427 316.015 1.00 141.19 ? 104 LYS A CB  1 
ATOM   683   C  CG  . LYS A 1 104 ? 206.756 217.389 317.340 1.00 141.19 ? 104 LYS A CG  1 
ATOM   684   C  CD  . LYS A 1 104 ? 207.380 218.336 318.352 1.00 141.19 ? 104 LYS A CD  1 
ATOM   685   C  CE  . LYS A 1 104 ? 206.668 218.260 319.692 1.00 141.19 ? 104 LYS A CE  1 
ATOM   686   N  NZ  . LYS A 1 104 ? 207.133 219.320 320.629 1.00 141.19 ? 104 LYS A NZ  1 
ATOM   687   N  N   . ASP A 1 105 ? 205.485 217.884 313.531 1.00 135.90 ? 105 ASP A N   1 
ATOM   688   C  CA  . ASP A 1 105 ? 204.224 218.420 313.040 1.00 135.90 ? 105 ASP A CA  1 
ATOM   689   C  C   . ASP A 1 105 ? 203.567 217.531 311.991 1.00 135.90 ? 105 ASP A C   1 
ATOM   690   O  O   . ASP A 1 105 ? 202.481 217.868 311.508 1.00 135.90 ? 105 ASP A O   1 
ATOM   691   C  CB  . ASP A 1 105 ? 204.437 219.826 312.468 1.00 135.90 ? 105 ASP A CB  1 
ATOM   692   C  CG  . ASP A 1 105 ? 205.545 219.874 311.435 1.00 135.90 ? 105 ASP A CG  1 
ATOM   693   O  OD1 . ASP A 1 105 ? 206.198 218.834 311.211 1.00 135.90 ? 105 ASP A OD1 1 
ATOM   694   O  OD2 . ASP A 1 105 ? 205.764 220.954 310.847 1.00 135.90 ? 105 ASP A OD2 1 
ATOM   695   N  N   . GLY A 1 106 ? 204.194 216.412 311.629 1.00 137.09 ? 106 GLY A N   1 
ATOM   696   C  CA  . GLY A 1 106 ? 203.633 215.490 310.668 1.00 137.09 ? 106 GLY A CA  1 
ATOM   697   C  C   . GLY A 1 106 ? 204.232 215.556 309.280 1.00 137.09 ? 106 GLY A C   1 
ATOM   698   O  O   . GLY A 1 106 ? 203.967 214.660 308.468 1.00 137.09 ? 106 GLY A O   1 
ATOM   699   N  N   . SER A 1 107 ? 205.026 216.580 308.979 1.00 135.80 ? 107 SER A N   1 
ATOM   700   C  CA  . SER A 1 107 ? 205.652 216.678 307.671 1.00 135.80 ? 107 SER A CA  1 
ATOM   701   C  C   . SER A 1 107 ? 206.693 215.576 307.491 1.00 135.80 ? 107 SER A C   1 
ATOM   702   O  O   . SER A 1 107 ? 207.332 215.124 308.445 1.00 135.80 ? 107 SER A O   1 
ATOM   703   C  CB  . SER A 1 107 ? 206.296 218.052 307.485 1.00 135.80 ? 107 SER A CB  1 
ATOM   704   O  OG  . SER A 1 107 ? 207.325 218.266 308.434 1.00 135.80 ? 107 SER A OG  1 
ATOM   705   N  N   . LYS A 1 108 ? 206.857 215.144 306.243 1.00 131.02 ? 108 LYS A N   1 
ATOM   706   C  CA  . LYS A 1 108 ? 207.754 214.049 305.904 1.00 131.02 ? 108 LYS A CA  1 
ATOM   707   C  C   . LYS A 1 108 ? 208.819 214.534 304.931 1.00 131.02 ? 108 LYS A C   1 
ATOM   708   O  O   . LYS A 1 108 ? 208.520 215.262 303.980 1.00 131.02 ? 108 LYS A O   1 
ATOM   709   C  CB  . LYS A 1 108 ? 206.984 212.873 305.293 1.00 131.02 ? 108 LYS A CB  1 
ATOM   710   C  CG  . LYS A 1 108 ? 205.994 212.220 306.244 1.00 131.02 ? 108 LYS A CG  1 
ATOM   711   C  CD  . LYS A 1 108 ? 205.250 211.081 305.566 1.00 131.02 ? 108 LYS A CD  1 
ATOM   712   C  CE  . LYS A 1 108 ? 204.265 210.420 306.516 1.00 131.02 ? 108 LYS A CE  1 
ATOM   713   N  NZ  . LYS A 1 108 ? 203.523 209.308 305.859 1.00 131.02 ? 108 LYS A NZ  1 
ATOM   714   N  N   . ILE A 1 109 ? 210.063 214.126 305.177 1.00 124.75 ? 109 ILE A N   1 
ATOM   715   C  CA  . ILE A 1 109 ? 211.209 214.470 304.349 1.00 124.75 ? 109 ILE A CA  1 
ATOM   716   C  C   . ILE A 1 109 ? 212.028 213.207 304.113 1.00 124.75 ? 109 ILE A C   1 
ATOM   717   O  O   . ILE A 1 109 ? 211.650 212.110 304.529 1.00 124.75 ? 109 ILE A O   1 
ATOM   718   C  CB  . ILE A 1 109 ? 212.082 215.572 304.985 1.00 124.75 ? 109 ILE A CB  1 
ATOM   719   C  CG1 . ILE A 1 109 ? 212.648 215.095 306.324 1.00 124.75 ? 109 ILE A CG1 1 
ATOM   720   C  CG2 . ILE A 1 109 ? 211.290 216.861 305.155 1.00 124.75 ? 109 ILE A CG2 1 
ATOM   721   C  CD1 . ILE A 1 109 ? 213.724 215.996 306.883 1.00 124.75 ? 109 ILE A CD1 1 
ATOM   722   N  N   . TRP A 1 110 ? 213.161 213.365 303.434 1.00 111.85 ? 110 TRP A N   1 
ATOM   723   C  CA  . TRP A 1 110 ? 214.103 212.279 303.210 1.00 111.85 ? 110 TRP A CA  1 
ATOM   724   C  C   . TRP A 1 110 ? 215.464 212.659 303.775 1.00 111.85 ? 110 TRP A C   1 
ATOM   725   O  O   . TRP A 1 110 ? 215.983 213.747 303.507 1.00 111.85 ? 110 TRP A O   1 
ATOM   726   C  CB  . TRP A 1 110 ? 214.227 211.949 301.723 1.00 111.85 ? 110 TRP A CB  1 
ATOM   727   C  CG  . TRP A 1 110 ? 213.276 210.898 301.278 1.00 111.85 ? 110 TRP A CG  1 
ATOM   728   C  CD1 . TRP A 1 110 ? 212.012 211.085 300.810 1.00 111.85 ? 110 TRP A CD1 1 
ATOM   729   C  CD2 . TRP A 1 110 ? 213.508 209.489 301.260 1.00 111.85 ? 110 TRP A CD2 1 
ATOM   730   N  NE1 . TRP A 1 110 ? 211.440 209.877 300.499 1.00 111.85 ? 110 TRP A NE1 1 
ATOM   731   C  CE2 . TRP A 1 110 ? 212.341 208.881 300.768 1.00 111.85 ? 110 TRP A CE2 1 
ATOM   732   C  CE3 . TRP A 1 110 ? 214.590 208.683 301.613 1.00 111.85 ? 110 TRP A CE3 1 
ATOM   733   C  CZ2 . TRP A 1 110 ? 212.226 207.504 300.619 1.00 111.85 ? 110 TRP A CZ2 1 
ATOM   734   C  CZ3 . TRP A 1 110 ? 214.474 207.323 301.462 1.00 111.85 ? 110 TRP A CZ3 1 
ATOM   735   C  CH2 . TRP A 1 110 ? 213.303 206.744 300.973 1.00 111.85 ? 110 TRP A CH2 1 
ATOM   736   N  N   . THR A 1 111 ? 216.046 211.753 304.561 1.00 113.08 ? 111 THR A N   1 
ATOM   737   C  CA  . THR A 1 111 ? 217.276 212.042 305.278 1.00 113.08 ? 111 THR A CA  1 
ATOM   738   C  C   . THR A 1 111 ? 218.307 210.959 305.013 1.00 113.08 ? 111 THR A C   1 
ATOM   739   O  O   . THR A 1 111 ? 217.974 209.806 304.720 1.00 113.08 ? 111 THR A O   1 
ATOM   740   C  CB  . THR A 1 111 ? 217.044 212.144 306.791 1.00 113.08 ? 111 THR A CB  1 
ATOM   741   O  OG1 . THR A 1 111 ? 216.892 210.828 307.335 1.00 113.08 ? 111 THR A OG1 1 
ATOM   742   C  CG2 . THR A 1 111 ? 215.799 212.962 307.098 1.00 113.08 ? 111 THR A CG2 1 
ATOM   743   N  N   . ARG A 1 112 ? 219.571 211.350 305.134 1.00 113.36 ? 112 ARG A N   1 
ATOM   744   C  CA  . ARG A 1 112 ? 220.706 210.449 305.007 1.00 113.36 ? 112 ARG A CA  1 
ATOM   745   C  C   . ARG A 1 112 ? 221.449 210.439 306.331 1.00 113.36 ? 112 ARG A C   1 
ATOM   746   O  O   . ARG A 1 112 ? 221.742 211.501 306.889 1.00 113.36 ? 112 ARG A O   1 
ATOM   747   C  CB  . ARG A 1 112 ? 221.632 210.883 303.869 1.00 113.36 ? 112 ARG A CB  1 
ATOM   748   C  CG  . ARG A 1 112 ? 222.687 209.855 303.492 1.00 113.36 ? 112 ARG A CG  1 
ATOM   749   C  CD  . ARG A 1 112 ? 224.045 210.211 304.078 1.00 113.36 ? 112 ARG A CD  1 
ATOM   750   N  NE  . ARG A 1 112 ? 225.125 209.452 303.458 1.00 113.36 ? 112 ARG A NE  1 
ATOM   751   C  CZ  . ARG A 1 112 ? 225.427 208.196 303.756 1.00 113.36 ? 112 ARG A CZ  1 
ATOM   752   N  NH1 . ARG A 1 112 ? 224.748 207.518 304.668 1.00 113.36 ? 112 ARG A NH1 1 
ATOM   753   N  NH2 . ARG A 1 112 ? 226.436 207.604 303.123 1.00 113.36 ? 112 ARG A NH2 1 
ATOM   754   N  N   . PHE A 1 113 ? 221.754 209.247 306.822 1.00 119.53 ? 113 PHE A N   1 
ATOM   755   C  CA  . PHE A 1 113 ? 222.384 209.065 308.118 1.00 119.53 ? 113 PHE A CA  1 
ATOM   756   C  C   . PHE A 1 113 ? 223.854 208.698 307.959 1.00 119.53 ? 113 PHE A C   1 
ATOM   757   O  O   . PHE A 1 113 ? 224.341 208.404 306.867 1.00 119.53 ? 113 PHE A O   1 
ATOM   758   C  CB  . PHE A 1 113 ? 221.662 207.976 308.914 1.00 119.53 ? 113 PHE A CB  1 
ATOM   759   C  CG  . PHE A 1 113 ? 220.238 208.307 309.254 1.00 119.53 ? 113 PHE A CG  1 
ATOM   760   C  CD1 . PHE A 1 113 ? 219.207 207.942 308.404 1.00 119.53 ? 113 PHE A CD1 1 
ATOM   761   C  CD2 . PHE A 1 113 ? 219.927 208.971 310.428 1.00 119.53 ? 113 PHE A CD2 1 
ATOM   762   C  CE1 . PHE A 1 113 ? 217.894 208.239 308.716 1.00 119.53 ? 113 PHE A CE1 1 
ATOM   763   C  CE2 . PHE A 1 113 ? 218.616 209.273 310.745 1.00 119.53 ? 113 PHE A CE2 1 
ATOM   764   C  CZ  . PHE A 1 113 ? 217.598 208.906 309.887 1.00 119.53 ? 113 PHE A CZ  1 
ATOM   765   N  N   . ALA A 1 114 ? 224.560 208.723 309.085 1.00 125.93 ? 114 ALA A N   1 
ATOM   766   C  CA  . ALA A 1 114 ? 225.955 208.296 309.140 1.00 125.93 ? 114 ALA A CA  1 
ATOM   767   C  C   . ALA A 1 114 ? 226.227 207.845 310.568 1.00 125.93 ? 114 ALA A C   1 
ATOM   768   O  O   . ALA A 1 114 ? 226.307 208.680 311.472 1.00 125.93 ? 114 ALA A O   1 
ATOM   769   C  CB  . ALA A 1 114 ? 226.890 209.424 308.727 1.00 125.93 ? 114 ALA A CB  1 
ATOM   770   N  N   . LEU A 1 115 ? 226.355 206.541 310.767 1.00 135.74 ? 115 LEU A N   1 
ATOM   771   C  CA  . LEU A 1 115 ? 226.419 205.969 312.101 1.00 135.74 ? 115 LEU A CA  1 
ATOM   772   C  C   . LEU A 1 115 ? 227.863 205.724 312.523 1.00 135.74 ? 115 LEU A C   1 
ATOM   773   O  O   . LEU A 1 115 ? 228.768 205.590 311.697 1.00 135.74 ? 115 LEU A O   1 
ATOM   774   C  CB  . LEU A 1 115 ? 225.621 204.663 312.158 1.00 135.74 ? 115 LEU A CB  1 
ATOM   775   C  CG  . LEU A 1 115 ? 225.402 203.977 313.512 1.00 135.74 ? 115 LEU A CG  1 
ATOM   776   C  CD1 . LEU A 1 115 ? 224.499 204.799 314.421 1.00 135.74 ? 115 LEU A CD1 1 
ATOM   777   C  CD2 . LEU A 1 115 ? 224.847 202.574 313.324 1.00 135.74 ? 115 LEU A CD2 1 
ATOM   778   N  N   . SER A 1 116 ? 228.064 205.677 313.838 1.00 146.87 ? 116 SER A N   1 
ATOM   779   C  CA  . SER A 1 116 ? 229.363 205.418 314.439 1.00 146.87 ? 116 SER A CA  1 
ATOM   780   C  C   . SER A 1 116 ? 229.146 204.930 315.863 1.00 146.87 ? 116 SER A C   1 
ATOM   781   O  O   . SER A 1 116 ? 228.087 205.145 316.457 1.00 146.87 ? 116 SER A O   1 
ATOM   782   C  CB  . SER A 1 116 ? 230.245 206.670 314.424 1.00 146.87 ? 116 SER A CB  1 
ATOM   783   O  OG  . SER A 1 116 ? 231.550 206.375 314.880 1.00 146.87 ? 116 SER A OG  1 
ATOM   784   N  N   . LYS A 1 117 ? 230.169 204.278 316.410 1.00 155.61 ? 117 LYS A N   1 
ATOM   785   C  CA  . LYS A 1 117 ? 230.130 203.768 317.774 1.00 155.61 ? 117 LYS A CA  1 
ATOM   786   C  C   . LYS A 1 117 ? 231.053 204.594 318.658 1.00 155.61 ? 117 LYS A C   1 
ATOM   787   O  O   . LYS A 1 117 ? 232.197 204.877 318.288 1.00 155.61 ? 117 LYS A O   1 
ATOM   788   C  CB  . LYS A 1 117 ? 230.529 202.291 317.831 1.00 155.61 ? 117 LYS A CB  1 
ATOM   789   C  CG  . LYS A 1 117 ? 230.368 201.666 319.208 1.00 155.61 ? 117 LYS A CG  1 
ATOM   790   C  CD  . LYS A 1 117 ? 230.560 200.160 319.157 1.00 155.61 ? 117 LYS A CD  1 
ATOM   791   C  CE  . LYS A 1 117 ? 229.437 199.492 318.378 1.00 155.61 ? 117 LYS A CE  1 
ATOM   792   N  NZ  . LYS A 1 117 ? 229.500 198.007 318.464 1.00 155.61 ? 117 LYS A NZ  1 
ATOM   793   N  N   . VAL A 1 118 ? 230.549 204.978 319.829 1.00 162.39 ? 118 VAL A N   1 
ATOM   794   C  CA  . VAL A 1 118 ? 231.264 205.841 320.762 1.00 162.39 ? 118 VAL A CA  1 
ATOM   795   C  C   . VAL A 1 118 ? 231.468 205.082 322.065 1.00 162.39 ? 118 VAL A C   1 
ATOM   796   O  O   . VAL A 1 118 ? 230.512 204.536 322.627 1.00 162.39 ? 118 VAL A O   1 
ATOM   797   C  CB  . VAL A 1 118 ? 230.503 207.156 321.012 1.00 162.39 ? 118 VAL A CB  1 
ATOM   798   C  CG1 . VAL A 1 118 ? 231.223 208.001 322.054 1.00 162.39 ? 118 VAL A CG1 1 
ATOM   799   C  CG2 . VAL A 1 118 ? 230.331 207.924 319.713 1.00 162.39 ? 118 VAL A CG2 1 
ATOM   800   N  N   . SER A 1 119 ? 232.710 205.049 322.541 1.00 168.78 ? 119 SER A N   1 
ATOM   801   C  CA  . SER A 1 119 ? 233.058 204.435 323.816 1.00 168.78 ? 119 SER A CA  1 
ATOM   802   C  C   . SER A 1 119 ? 233.592 205.514 324.748 1.00 168.78 ? 119 SER A C   1 
ATOM   803   O  O   . SER A 1 119 ? 234.667 206.074 324.502 1.00 168.78 ? 119 SER A O   1 
ATOM   804   C  CB  . SER A 1 119 ? 234.090 203.324 323.628 1.00 168.78 ? 119 SER A CB  1 
ATOM   805   O  OG  . SER A 1 119 ? 234.464 202.758 324.872 1.00 168.78 ? 119 SER A OG  1 
ATOM   806   N  N   . ALA A 1 120 ? 232.846 205.803 325.813 1.00 172.71 ? 120 ALA A N   1 
ATOM   807   C  CA  . ALA A 1 120 ? 233.239 206.836 326.760 1.00 172.71 ? 120 ALA A CA  1 
ATOM   808   C  C   . ALA A 1 120 ? 232.618 206.542 328.117 1.00 172.71 ? 120 ALA A C   1 
ATOM   809   O  O   . ALA A 1 120 ? 231.533 205.959 328.206 1.00 172.71 ? 120 ALA A O   1 
ATOM   810   C  CB  . ALA A 1 120 ? 232.824 208.230 326.278 1.00 172.71 ? 120 ALA A CB  1 
ATOM   811   N  N   . GLU A 1 121 ? 233.324 206.956 329.172 1.00 176.77 ? 121 GLU A N   1 
ATOM   812   C  CA  . GLU A 1 121 ? 232.868 206.788 330.555 1.00 176.77 ? 121 GLU A CA  1 
ATOM   813   C  C   . GLU A 1 121 ? 232.585 205.323 330.881 1.00 176.77 ? 121 GLU A C   1 
ATOM   814   O  O   . GLU A 1 121 ? 231.665 205.006 331.638 1.00 176.77 ? 121 GLU A O   1 
ATOM   815   C  CB  . GLU A 1 121 ? 231.636 207.651 330.841 1.00 176.77 ? 121 GLU A CB  1 
ATOM   816   C  CG  . GLU A 1 121 ? 231.807 209.118 330.484 1.00 176.77 ? 121 GLU A CG  1 
ATOM   817   C  CD  . GLU A 1 121 ? 230.589 209.950 330.837 1.00 176.77 ? 121 GLU A CD  1 
ATOM   818   O  OE1 . GLU A 1 121 ? 229.517 209.721 330.238 1.00 176.77 ? 121 GLU A OE1 1 
ATOM   819   O  OE2 . GLU A 1 121 ? 230.703 210.832 331.714 1.00 176.77 ? 121 GLU A OE2 1 
ATOM   820   N  N   . GLY A 1 122 ? 233.380 204.420 330.311 1.00 172.54 ? 122 GLY A N   1 
ATOM   821   C  CA  . GLY A 1 122 ? 233.180 203.004 330.544 1.00 172.54 ? 122 GLY A CA  1 
ATOM   822   C  C   . GLY A 1 122 ? 231.907 202.440 329.957 1.00 172.54 ? 122 GLY A C   1 
ATOM   823   O  O   . GLY A 1 122 ? 231.465 201.367 330.376 1.00 172.54 ? 122 GLY A O   1 
ATOM   824   N  N   . LYS A 1 123 ? 231.302 203.133 328.996 1.00 167.96 ? 123 LYS A N   1 
ATOM   825   C  CA  . LYS A 1 123 ? 230.059 202.708 328.372 1.00 167.96 ? 123 LYS A CA  1 
ATOM   826   C  C   . LYS A 1 123 ? 230.174 202.869 326.862 1.00 167.96 ? 123 LYS A C   1 
ATOM   827   O  O   . LYS A 1 123 ? 231.066 203.553 326.351 1.00 167.96 ? 123 LYS A O   1 
ATOM   828   C  CB  . LYS A 1 123 ? 228.862 203.508 328.905 1.00 167.96 ? 123 LYS A CB  1 
ATOM   829   C  CG  . LYS A 1 123 ? 228.618 203.353 330.397 1.00 167.96 ? 123 LYS A CG  1 
ATOM   830   C  CD  . LYS A 1 123 ? 227.754 204.483 330.934 1.00 167.96 ? 123 LYS A CD  1 
ATOM   831   C  CE  . LYS A 1 123 ? 227.604 204.395 332.444 1.00 167.96 ? 123 LYS A CE  1 
ATOM   832   N  NZ  . LYS A 1 123 ? 226.889 205.577 332.999 1.00 167.96 ? 123 LYS A NZ  1 
ATOM   833   N  N   . VAL A 1 124 ? 229.256 202.228 326.144 1.00 162.31 ? 124 VAL A N   1 
ATOM   834   C  CA  . VAL A 1 124 ? 229.225 202.256 324.686 1.00 162.31 ? 124 VAL A CA  1 
ATOM   835   C  C   . VAL A 1 124 ? 228.038 203.105 324.253 1.00 162.31 ? 124 VAL A C   1 
ATOM   836   O  O   . VAL A 1 124 ? 226.889 202.809 324.605 1.00 162.31 ? 124 VAL A O   1 
ATOM   837   C  CB  . VAL A 1 124 ? 229.139 200.843 324.092 1.00 162.31 ? 124 VAL A CB  1 
ATOM   838   C  CG1 . VAL A 1 124 ? 228.985 200.912 322.582 1.00 162.31 ? 124 VAL A CG1 1 
ATOM   839   C  CG2 . VAL A 1 124 ? 230.369 200.032 324.472 1.00 162.31 ? 124 VAL A CG2 1 
ATOM   840   N  N   . TYR A 1 125 ? 228.315 204.159 323.493 1.00 161.83 ? 125 TYR A N   1 
ATOM   841   C  CA  . TYR A 1 125 ? 227.297 205.066 322.985 1.00 161.83 ? 125 TYR A CA  1 
ATOM   842   C  C   . TYR A 1 125 ? 227.230 204.945 321.467 1.00 161.83 ? 125 TYR A C   1 
ATOM   843   O  O   . TYR A 1 125 ? 228.116 204.376 320.825 1.00 161.83 ? 125 TYR A O   1 
ATOM   844   C  CB  . TYR A 1 125 ? 227.590 206.516 323.395 1.00 161.83 ? 125 TYR A CB  1 
ATOM   845   C  CG  . TYR A 1 125 ? 227.644 206.758 324.892 1.00 161.83 ? 125 TYR A CG  1 
ATOM   846   C  CD1 . TYR A 1 125 ? 227.125 205.834 325.791 1.00 161.83 ? 125 TYR A CD1 1 
ATOM   847   C  CD2 . TYR A 1 125 ? 228.220 207.914 325.403 1.00 161.83 ? 125 TYR A CD2 1 
ATOM   848   C  CE1 . TYR A 1 125 ? 227.174 206.057 327.154 1.00 161.83 ? 125 TYR A CE1 1 
ATOM   849   C  CE2 . TYR A 1 125 ? 228.275 208.144 326.765 1.00 161.83 ? 125 TYR A CE2 1 
ATOM   850   C  CZ  . TYR A 1 125 ? 227.751 207.213 327.635 1.00 161.83 ? 125 TYR A CZ  1 
ATOM   851   O  OH  . TYR A 1 125 ? 227.806 207.440 328.991 1.00 161.83 ? 125 TYR A OH  1 
ATOM   852   N  N   . TYR A 1 126 ? 226.160 205.484 320.890 1.00 155.80 ? 126 TYR A N   1 
ATOM   853   C  CA  . TYR A 1 126 ? 225.940 205.410 319.451 1.00 155.80 ? 126 TYR A CA  1 
ATOM   854   C  C   . TYR A 1 126 ? 225.743 206.808 318.881 1.00 155.80 ? 126 TYR A C   1 
ATOM   855   O  O   . TYR A 1 126 ? 224.884 207.560 319.353 1.00 155.80 ? 126 TYR A O   1 
ATOM   856   C  CB  . TYR A 1 126 ? 224.730 204.533 319.127 1.00 155.80 ? 126 TYR A CB  1 
ATOM   857   C  CG  . TYR A 1 126 ? 224.747 203.180 319.800 1.00 155.80 ? 126 TYR A CG  1 
ATOM   858   C  CD1 . TYR A 1 126 ? 225.505 202.136 319.286 1.00 155.80 ? 126 TYR A CD1 1 
ATOM   859   C  CD2 . TYR A 1 126 ? 224.003 202.945 320.948 1.00 155.80 ? 126 TYR A CD2 1 
ATOM   860   C  CE1 . TYR A 1 126 ? 225.521 200.895 319.897 1.00 155.80 ? 126 TYR A CE1 1 
ATOM   861   C  CE2 . TYR A 1 126 ? 224.011 201.709 321.565 1.00 155.80 ? 126 TYR A CE2 1 
ATOM   862   C  CZ  . TYR A 1 126 ? 224.773 200.688 321.036 1.00 155.80 ? 126 TYR A CZ  1 
ATOM   863   O  OH  . TYR A 1 126 ? 224.785 199.455 321.650 1.00 155.80 ? 126 TYR A OH  1 
ATOM   864   N  N   . LEU A 1 127 ? 226.524 207.142 317.853 1.00 148.90 ? 127 LEU A N   1 
ATOM   865   C  CA  . LEU A 1 127 ? 226.503 208.448 317.206 1.00 148.90 ? 127 LEU A CA  1 
ATOM   866   C  C   . LEU A 1 127 ? 225.846 208.320 315.840 1.00 148.90 ? 127 LEU A C   1 
ATOM   867   O  O   . LEU A 1 127 ? 226.153 207.391 315.089 1.00 148.90 ? 127 LEU A O   1 
ATOM   868   C  CB  . LEU A 1 127 ? 227.919 209.001 317.054 1.00 148.90 ? 127 LEU A CB  1 
ATOM   869   C  CG  . LEU A 1 127 ? 228.026 210.359 316.360 1.00 148.90 ? 127 LEU A CG  1 
ATOM   870   C  CD1 . LEU A 1 127 ? 227.311 211.406 317.175 1.00 148.90 ? 127 LEU A CD1 1 
ATOM   871   C  CD2 . LEU A 1 127 ? 229.481 210.742 316.139 1.00 148.90 ? 127 LEU A CD2 1 
ATOM   872   N  N   . ALA A 1 128 ? 224.958 209.252 315.515 1.00 144.57 ? 128 ALA A N   1 
ATOM   873   C  CA  . ALA A 1 128 ? 224.293 209.289 314.215 1.00 144.57 ? 128 ALA A CA  1 
ATOM   874   C  C   . ALA A 1 128 ? 224.284 210.732 313.723 1.00 144.57 ? 128 ALA A C   1 
ATOM   875   O  O   . ALA A 1 128 ? 223.617 211.592 314.307 1.00 144.57 ? 128 ALA A O   1 
ATOM   876   C  CB  . ALA A 1 128 ? 222.879 208.723 314.304 1.00 144.57 ? 128 ALA A CB  1 
ATOM   877   N  N   . LEU A 1 129 ? 225.035 211.002 312.662 1.00 132.77 ? 129 LEU A N   1 
ATOM   878   C  CA  . LEU A 1 129 ? 224.913 212.271 311.966 1.00 132.77 ? 129 LEU A CA  1 
ATOM   879   C  C   . LEU A 1 129 ? 223.818 212.170 310.912 1.00 132.77 ? 129 LEU A C   1 
ATOM   880   O  O   . LEU A 1 129 ? 223.608 211.127 310.296 1.00 132.77 ? 129 LEU A O   1 
ATOM   881   C  CB  . LEU A 1 129 ? 226.237 212.678 311.325 1.00 132.77 ? 129 LEU A CB  1 
ATOM   882   C  CG  . LEU A 1 129 ? 227.456 212.653 312.239 1.00 132.77 ? 129 LEU A CG  1 
ATOM   883   C  CD1 . LEU A 1 129 ? 228.656 213.219 311.509 1.00 132.77 ? 129 LEU A CD1 1 
ATOM   884   C  CD2 . LEU A 1 129 ? 227.184 213.431 313.510 1.00 132.77 ? 129 LEU A CD2 1 
ATOM   885   N  N   . VAL A 1 130 ? 223.101 213.269 310.730 1.00 127.94 ? 130 VAL A N   1 
ATOM   886   C  CA  . VAL A 1 130 ? 221.928 213.295 309.866 1.00 127.94 ? 130 VAL A CA  1 
ATOM   887   C  C   . VAL A 1 130 ? 222.020 214.511 308.956 1.00 127.94 ? 130 VAL A C   1 
ATOM   888   O  O   . VAL A 1 130 ? 222.396 215.605 309.391 1.00 127.94 ? 130 VAL A O   1 
ATOM   889   C  CB  . VAL A 1 130 ? 220.624 213.311 310.692 1.00 127.94 ? 130 VAL A CB  1 
ATOM   890   C  CG1 . VAL A 1 130 ? 219.409 213.239 309.777 1.00 127.94 ? 130 VAL A CG1 1 
ATOM   891   C  CG2 . VAL A 1 130 ? 220.613 212.167 311.692 1.00 127.94 ? 130 VAL A CG2 1 
ATOM   892   N  N   . ARG A 1 131 ? 221.681 214.307 307.685 1.00 113.68 ? 131 ARG A N   1 
ATOM   893   C  CA  . ARG A 1 131 ? 221.587 215.378 306.711 1.00 113.68 ? 131 ARG A CA  1 
ATOM   894   C  C   . ARG A 1 131 ? 220.262 215.255 305.982 1.00 113.68 ? 131 ARG A C   1 
ATOM   895   O  O   . ARG A 1 131 ? 219.746 214.155 305.781 1.00 113.68 ? 131 ARG A O   1 
ATOM   896   C  CB  . ARG A 1 131 ? 222.750 215.331 305.718 1.00 113.68 ? 131 ARG A CB  1 
ATOM   897   C  CG  . ARG A 1 131 ? 222.724 216.425 304.671 1.00 113.68 ? 131 ARG A CG  1 
ATOM   898   C  CD  . ARG A 1 131 ? 222.897 217.793 305.304 1.00 113.68 ? 131 ARG A CD  1 
ATOM   899   N  NE  . ARG A 1 131 ? 223.940 217.805 306.323 1.00 113.68 ? 131 ARG A NE  1 
ATOM   900   C  CZ  . ARG A 1 131 ? 225.240 217.746 306.068 1.00 113.68 ? 131 ARG A CZ  1 
ATOM   901   N  NH1 . ARG A 1 131 ? 225.700 217.663 304.830 1.00 113.68 ? 131 ARG A NH1 1 
ATOM   902   N  NH2 . ARG A 1 131 ? 226.100 217.779 307.080 1.00 113.68 ? 131 ARG A NH2 1 
ATOM   903   N  N   . ASP A 1 132 ? 219.700 216.397 305.601 1.00 108.73 ? 132 ASP A N   1 
ATOM   904   C  CA  . ASP A 1 132 ? 218.466 216.411 304.823 1.00 108.73 ? 132 ASP A CA  1 
ATOM   905   C  C   . ASP A 1 132 ? 218.797 216.027 303.387 1.00 108.73 ? 132 ASP A C   1 
ATOM   906   O  O   . ASP A 1 132 ? 219.324 216.838 302.619 1.00 108.73 ? 132 ASP A O   1 
ATOM   907   C  CB  . ASP A 1 132 ? 217.790 217.777 304.891 1.00 108.73 ? 132 ASP A CB  1 
ATOM   908   C  CG  . ASP A 1 132 ? 218.756 218.923 304.667 1.00 108.73 ? 132 ASP A CG  1 
ATOM   909   O  OD1 . ASP A 1 132 ? 219.976 218.674 304.613 1.00 108.73 ? 132 ASP A OD1 1 
ATOM   910   O  OD2 . ASP A 1 132 ? 218.292 220.077 304.544 1.00 108.73 ? 132 ASP A OD2 1 
ATOM   911   N  N   . ALA A 1 133 ? 218.488 214.785 303.022 1.00 101.13 ? 133 ALA A N   1 
ATOM   912   C  CA  . ALA A 1 133 ? 218.822 214.291 301.695 1.00 101.13 ? 133 ALA A CA  1 
ATOM   913   C  C   . ALA A 1 133 ? 217.845 214.758 300.631 1.00 101.13 ? 133 ALA A C   1 
ATOM   914   O  O   . ALA A 1 133 ? 217.807 214.159 299.554 1.00 101.13 ? 133 ALA A O   1 
ATOM   915   C  CB  . ALA A 1 133 ? 218.883 212.763 301.704 1.00 101.13 ? 133 ALA A CB  1 
ATOM   916   N  N   . SER A 1 134 ? 217.039 215.784 300.912 1.00 90.81  ? 134 SER A N   1 
ATOM   917   C  CA  . SER A 1 134 ? 216.086 216.271 299.922 1.00 90.81  ? 134 SER A CA  1 
ATOM   918   C  C   . SER A 1 134 ? 216.794 216.867 298.714 1.00 90.81  ? 134 SER A C   1 
ATOM   919   O  O   . SER A 1 134 ? 216.367 216.661 297.575 1.00 90.81  ? 134 SER A O   1 
ATOM   920   C  CB  . SER A 1 134 ? 215.151 217.298 300.556 1.00 90.81  ? 134 SER A CB  1 
ATOM   921   O  OG  . SER A 1 134 ? 214.433 216.730 301.637 1.00 90.81  ? 134 SER A OG  1 
ATOM   922   N  N   . VAL A 1 135 ? 217.889 217.595 298.939 1.00 85.10  ? 135 VAL A N   1 
ATOM   923   C  CA  . VAL A 1 135 ? 218.612 218.238 297.852 1.00 85.10  ? 135 VAL A CA  1 
ATOM   924   C  C   . VAL A 1 135 ? 219.270 217.242 296.905 1.00 85.10  ? 135 VAL A C   1 
ATOM   925   O  O   . VAL A 1 135 ? 219.759 217.640 295.846 1.00 85.10  ? 135 VAL A O   1 
ATOM   926   C  CB  . VAL A 1 135 ? 219.670 219.209 298.415 1.00 85.10  ? 135 VAL A CB  1 
ATOM   927   C  CG1 . VAL A 1 135 ? 219.000 220.294 299.239 1.00 85.10  ? 135 VAL A CG1 1 
ATOM   928   C  CG2 . VAL A 1 135 ? 220.692 218.452 299.246 1.00 85.10  ? 135 VAL A CG2 1 
ATOM   929   N  N   . GLU A 1 136 ? 219.304 215.962 297.264 1.00 77.86  ? 136 GLU A N   1 
ATOM   930   C  CA  . GLU A 1 136 ? 219.805 214.898 296.404 1.00 77.86  ? 136 GLU A CA  1 
ATOM   931   C  C   . GLU A 1 136 ? 218.708 213.981 295.889 1.00 77.86  ? 136 GLU A C   1 
ATOM   932   O  O   . GLU A 1 136 ? 218.737 213.566 294.723 1.00 77.86  ? 136 GLU A O   1 
ATOM   933   C  CB  . GLU A 1 136 ? 220.849 214.073 297.160 1.00 77.86  ? 136 GLU A CB  1 
ATOM   934   C  CG  . GLU A 1 136 ? 221.123 212.718 296.568 1.00 77.86  ? 136 GLU A CG  1 
ATOM   935   C  CD  . GLU A 1 136 ? 222.237 211.987 297.287 1.00 77.86  ? 136 GLU A CD  1 
ATOM   936   O  OE1 . GLU A 1 136 ? 222.771 212.538 298.272 1.00 77.86  ? 136 GLU A OE1 1 
ATOM   937   O  OE2 . GLU A 1 136 ? 222.578 210.861 296.868 1.00 77.86  ? 136 GLU A OE2 1 
ATOM   938   N  N   . MET A 1 137 ? 217.730 213.652 296.730 1.00 72.83  ? 137 MET A N   1 
ATOM   939   C  CA  . MET A 1 137 ? 216.592 212.886 296.257 1.00 72.83  ? 137 MET A CA  1 
ATOM   940   C  C   . MET A 1 137 ? 215.764 213.676 295.262 1.00 72.83  ? 137 MET A C   1 
ATOM   941   O  O   . MET A 1 137 ? 215.047 213.075 294.458 1.00 72.83  ? 137 MET A O   1 
ATOM   942   C  CB  . MET A 1 137 ? 215.731 212.439 297.431 1.00 72.83  ? 137 MET A CB  1 
ATOM   943   C  CG  . MET A 1 137 ? 214.782 211.318 297.087 1.00 72.83  ? 137 MET A CG  1 
ATOM   944   S  SD  . MET A 1 137 ? 215.645 209.899 296.396 1.00 72.83  ? 137 MET A SD  1 
ATOM   945   C  CE  . MET A 1 137 ? 216.523 209.300 297.831 1.00 72.83  ? 137 MET A CE  1 
ATOM   946   N  N   . ALA A 1 138 ? 215.874 215.004 295.274 1.00 66.95  ? 138 ALA A N   1 
ATOM   947   C  CA  . ALA A 1 138 ? 215.299 215.799 294.200 1.00 66.95  ? 138 ALA A CA  1 
ATOM   948   C  C   . ALA A 1 138 ? 215.925 215.428 292.866 1.00 66.95  ? 138 ALA A C   1 
ATOM   949   O  O   . ALA A 1 138 ? 215.219 215.227 291.875 1.00 66.95  ? 138 ALA A O   1 
ATOM   950   C  CB  . ALA A 1 138 ? 215.490 217.286 294.491 1.00 66.95  ? 138 ALA A CB  1 
ATOM   951   N  N   . GLN A 1 139 ? 217.255 215.302 292.828 1.00 63.72  ? 139 GLN A N   1 
ATOM   952   C  CA  . GLN A 1 139 ? 217.926 214.892 291.597 1.00 63.72  ? 139 GLN A CA  1 
ATOM   953   C  C   . GLN A 1 139 ? 217.573 213.459 291.225 1.00 63.72  ? 139 GLN A C   1 
ATOM   954   O  O   . GLN A 1 139 ? 217.431 213.135 290.040 1.00 63.72  ? 139 GLN A O   1 
ATOM   955   C  CB  . GLN A 1 139 ? 219.438 215.043 291.738 1.00 63.72  ? 139 GLN A CB  1 
ATOM   956   C  CG  . GLN A 1 139 ? 219.913 216.468 291.711 1.00 63.72  ? 139 GLN A CG  1 
ATOM   957   C  CD  . GLN A 1 139 ? 219.760 217.094 290.348 1.00 63.72  ? 139 GLN A CD  1 
ATOM   958   O  OE1 . GLN A 1 139 ? 219.910 216.424 289.333 1.00 63.72  ? 139 GLN A OE1 1 
ATOM   959   N  NE2 . GLN A 1 139 ? 219.463 218.383 290.315 1.00 63.72  ? 139 GLN A NE2 1 
ATOM   960   N  N   . LYS A 1 140 ? 217.448 212.586 292.221 1.00 65.11  ? 140 LYS A N   1 
ATOM   961   C  CA  . LYS A 1 140 ? 217.096 211.198 291.936 1.00 65.11  ? 140 LYS A CA  1 
ATOM   962   C  C   . LYS A 1 140 ? 215.717 211.099 291.294 1.00 65.11  ? 140 LYS A C   1 
ATOM   963   O  O   . LYS A 1 140 ? 215.545 210.450 290.254 1.00 65.11  ? 140 LYS A O   1 
ATOM   964   C  CB  . LYS A 1 140 ? 217.149 210.371 293.216 1.00 65.11  ? 140 LYS A CB  1 
ATOM   965   C  CG  . LYS A 1 140 ? 218.548 210.130 293.729 1.00 65.11  ? 140 LYS A CG  1 
ATOM   966   C  CD  . LYS A 1 140 ? 219.201 208.972 293.012 1.00 65.11  ? 140 LYS A CD  1 
ATOM   967   C  CE  . LYS A 1 140 ? 220.705 209.036 293.166 1.00 65.11  ? 140 LYS A CE  1 
ATOM   968   N  NZ  . LYS A 1 140 ? 221.191 210.436 293.055 1.00 65.11  ? 140 LYS A NZ  1 
ATOM   969   N  N   . GLU A 1 141 ? 214.716 211.738 291.901 1.00 65.91  ? 141 GLU A N   1 
ATOM   970   C  CA  . GLU A 1 141 ? 213.382 211.757 291.319 1.00 65.91  ? 141 GLU A CA  1 
ATOM   971   C  C   . GLU A 1 141 ? 213.321 212.567 290.036 1.00 65.91  ? 141 GLU A C   1 
ATOM   972   O  O   . GLU A 1 141 ? 212.408 212.355 289.232 1.00 65.91  ? 141 GLU A O   1 
ATOM   973   C  CB  . GLU A 1 141 ? 212.374 212.307 292.324 1.00 65.91  ? 141 GLU A CB  1 
ATOM   974   C  CG  . GLU A 1 141 ? 210.929 211.963 292.008 1.00 65.91  ? 141 GLU A CG  1 
ATOM   975   C  CD  . GLU A 1 141 ? 210.533 210.576 292.480 1.00 65.91  ? 141 GLU A CD  1 
ATOM   976   O  OE1 . GLU A 1 141 ? 211.430 209.741 292.718 1.00 65.91  ? 141 GLU A OE1 1 
ATOM   977   O  OE2 . GLU A 1 141 ? 209.318 210.320 292.613 1.00 65.91  ? 141 GLU A OE2 1 
ATOM   978   N  N   . GLN A 1 142 ? 214.257 213.489 289.831 1.00 59.76  ? 142 GLN A N   1 
ATOM   979   C  CA  . GLN A 1 142 ? 214.356 214.188 288.561 1.00 59.76  ? 142 GLN A CA  1 
ATOM   980   C  C   . GLN A 1 142 ? 214.788 213.249 287.444 1.00 59.76  ? 142 GLN A C   1 
ATOM   981   O  O   . GLN A 1 142 ? 214.137 213.173 286.394 1.00 59.76  ? 142 GLN A O   1 
ATOM   982   C  CB  . GLN A 1 142 ? 215.343 215.342 288.695 1.00 59.76  ? 142 GLN A CB  1 
ATOM   983   C  CG  . GLN A 1 142 ? 214.704 216.664 288.999 1.00 59.76  ? 142 GLN A CG  1 
ATOM   984   C  CD  . GLN A 1 142 ? 214.184 217.333 287.757 1.00 59.76  ? 142 GLN A CD  1 
ATOM   985   O  OE1 . GLN A 1 142 ? 214.956 217.736 286.890 1.00 59.76  ? 142 GLN A OE1 1 
ATOM   986   N  NE2 . GLN A 1 142 ? 212.869 217.457 287.659 1.00 59.76  ? 142 GLN A NE2 1 
ATOM   987   N  N   . THR A 1 143 ? 215.878 212.514 287.659 1.00 57.10  ? 143 THR A N   1 
ATOM   988   C  CA  . THR A 1 143 ? 216.393 211.659 286.597 1.00 57.10  ? 143 THR A CA  1 
ATOM   989   C  C   . THR A 1 143 ? 215.480 210.467 286.361 1.00 57.10  ? 143 THR A C   1 
ATOM   990   O  O   . THR A 1 143 ? 215.328 210.009 285.221 1.00 57.10  ? 143 THR A O   1 
ATOM   991   C  CB  . THR A 1 143 ? 217.812 211.195 286.913 1.00 57.10  ? 143 THR A CB  1 
ATOM   992   O  OG1 . THR A 1 143 ? 218.264 210.322 285.874 1.00 57.10  ? 143 THR A OG1 1 
ATOM   993   C  CG2 . THR A 1 143 ? 217.873 210.461 288.228 1.00 57.10  ? 143 THR A CG2 1 
ATOM   994   N  N   . ARG A 1 144 ? 214.854 209.951 287.425 1.00 60.40  ? 144 ARG A N   1 
ATOM   995   C  CA  . ARG A 1 144 ? 213.910 208.853 287.256 1.00 60.40  ? 144 ARG A CA  1 
ATOM   996   C  C   . ARG A 1 144 ? 212.761 209.266 286.353 1.00 60.40  ? 144 ARG A C   1 
ATOM   997   O  O   . ARG A 1 144 ? 212.288 208.473 285.533 1.00 60.40  ? 144 ARG A O   1 
ATOM   998   C  CB  . ARG A 1 144 ? 213.390 208.397 288.618 1.00 60.40  ? 144 ARG A CB  1 
ATOM   999   C  CG  . ARG A 1 144 ? 213.018 206.924 288.711 1.00 60.40  ? 144 ARG A CG  1 
ATOM   1000  C  CD  . ARG A 1 144 ? 211.618 206.654 288.183 1.00 60.40  ? 144 ARG A CD  1 
ATOM   1001  N  NE  . ARG A 1 144 ? 210.658 207.666 288.610 1.00 60.40  ? 144 ARG A NE  1 
ATOM   1002  C  CZ  . ARG A 1 144 ? 210.169 207.773 289.837 1.00 60.40  ? 144 ARG A CZ  1 
ATOM   1003  N  NH1 . ARG A 1 144 ? 210.522 206.936 290.797 1.00 60.40  ? 144 ARG A NH1 1 
ATOM   1004  N  NH2 . ARG A 1 144 ? 209.302 208.743 290.106 1.00 60.40  ? 144 ARG A NH2 1 
ATOM   1005  N  N   . GLN A 1 145 ? 212.302 210.509 286.487 1.00 59.63  ? 145 GLN A N   1 
ATOM   1006  C  CA  . GLN A 1 145 ? 211.206 210.981 285.654 1.00 59.63  ? 145 GLN A CA  1 
ATOM   1007  C  C   . GLN A 1 145 ? 211.681 211.299 284.245 1.00 59.63  ? 145 GLN A C   1 
ATOM   1008  O  O   . GLN A 1 145 ? 210.941 211.097 283.275 1.00 59.63  ? 145 GLN A O   1 
ATOM   1009  C  CB  . GLN A 1 145 ? 210.554 212.207 286.288 1.00 59.63  ? 145 GLN A CB  1 
ATOM   1010  C  CG  . GLN A 1 145 ? 209.575 211.873 287.397 1.00 59.63  ? 145 GLN A CG  1 
ATOM   1011  C  CD  . GLN A 1 145 ? 208.865 213.093 287.935 1.00 59.63  ? 145 GLN A CD  1 
ATOM   1012  O  OE1 . GLN A 1 145 ? 207.662 213.256 287.748 1.00 59.63  ? 145 GLN A OE1 1 
ATOM   1013  N  NE2 . GLN A 1 145 ? 209.608 213.957 288.612 1.00 59.63  ? 145 GLN A NE2 1 
ATOM   1014  N  N   . LEU A 1 146 ? 212.909 211.802 284.110 1.00 53.67  ? 146 LEU A N   1 
ATOM   1015  C  CA  . LEU A 1 146 ? 213.408 212.163 282.788 1.00 53.67  ? 146 LEU A CA  1 
ATOM   1016  C  C   . LEU A 1 146 ? 213.677 210.932 281.938 1.00 53.67  ? 146 LEU A C   1 
ATOM   1017  O  O   . LEU A 1 146 ? 213.565 210.984 280.708 1.00 53.67  ? 146 LEU A O   1 
ATOM   1018  C  CB  . LEU A 1 146 ? 214.671 213.003 282.915 1.00 53.67  ? 146 LEU A CB  1 
ATOM   1019  C  CG  . LEU A 1 146 ? 214.432 214.469 283.237 1.00 53.67  ? 146 LEU A CG  1 
ATOM   1020  C  CD1 . LEU A 1 146 ? 215.574 215.020 284.063 1.00 53.67  ? 146 LEU A CD1 1 
ATOM   1021  C  CD2 . LEU A 1 146 ? 214.276 215.246 281.952 1.00 53.67  ? 146 LEU A CD2 1 
ATOM   1022  N  N   . ILE A 1 147 ? 214.063 209.823 282.571 1.00 52.73  ? 147 ILE A N   1 
ATOM   1023  C  CA  . ILE A 1 147 ? 214.336 208.605 281.817 1.00 52.73  ? 147 ILE A CA  1 
ATOM   1024  C  C   . ILE A 1 147 ? 213.092 208.137 281.083 1.00 52.73  ? 147 ILE A C   1 
ATOM   1025  O  O   . ILE A 1 147 ? 213.170 207.688 279.934 1.00 52.73  ? 147 ILE A O   1 
ATOM   1026  C  CB  . ILE A 1 147 ? 214.891 207.520 282.755 1.00 52.73  ? 147 ILE A CB  1 
ATOM   1027  C  CG1 . ILE A 1 147 ? 216.369 207.773 283.028 1.00 52.73  ? 147 ILE A CG1 1 
ATOM   1028  C  CG2 . ILE A 1 147 ? 214.704 206.142 282.167 1.00 52.73  ? 147 ILE A CG2 1 
ATOM   1029  C  CD1 . ILE A 1 147 ? 216.916 206.977 284.183 1.00 52.73  ? 147 ILE A CD1 1 
ATOM   1030  N  N   . ILE A 1 148 ? 211.925 208.248 281.719 1.00 54.96  ? 148 ILE A N   1 
ATOM   1031  C  CA  . ILE A 1 148 ? 210.683 207.836 281.070 1.00 54.96  ? 148 ILE A CA  1 
ATOM   1032  C  C   . ILE A 1 148 ? 210.437 208.674 279.823 1.00 54.96  ? 148 ILE A C   1 
ATOM   1033  O  O   . ILE A 1 148 ? 210.084 208.151 278.758 1.00 54.96  ? 148 ILE A O   1 
ATOM   1034  C  CB  . ILE A 1 148 ? 209.504 207.934 282.054 1.00 54.96  ? 148 ILE A CB  1 
ATOM   1035  C  CG1 . ILE A 1 148 ? 209.923 207.489 283.454 1.00 54.96  ? 148 ILE A CG1 1 
ATOM   1036  C  CG2 . ILE A 1 148 ? 208.359 207.074 281.580 1.00 54.96  ? 148 ILE A CG2 1 
ATOM   1037  C  CD1 . ILE A 1 148 ? 210.367 206.045 283.534 1.00 54.96  ? 148 ILE A CD1 1 
ATOM   1038  N  N   . ALA A 1 149 ? 210.630 209.988 279.937 1.00 52.05  ? 149 ALA A N   1 
ATOM   1039  C  CA  . ALA A 1 149 ? 210.436 210.870 278.795 1.00 52.05  ? 149 ALA A CA  1 
ATOM   1040  C  C   . ALA A 1 149 ? 211.416 210.551 277.677 1.00 52.05  ? 149 ALA A C   1 
ATOM   1041  O  O   . ALA A 1 149 ? 211.038 210.516 276.500 1.00 52.05  ? 149 ALA A O   1 
ATOM   1042  C  CB  . ALA A 1 149 ? 210.581 212.325 279.233 1.00 52.05  ? 149 ALA A CB  1 
ATOM   1043  N  N   . VAL A 1 150 ? 212.682 210.309 278.023 1.00 50.75  ? 150 VAL A N   1 
ATOM   1044  C  CA  . VAL A 1 150 ? 213.689 210.084 276.992 1.00 50.75  ? 150 VAL A CA  1 
ATOM   1045  C  C   . VAL A 1 150 ? 213.522 208.706 276.371 1.00 50.75  ? 150 VAL A C   1 
ATOM   1046  O  O   . VAL A 1 150 ? 214.011 208.456 275.264 1.00 50.75  ? 150 VAL A O   1 
ATOM   1047  C  CB  . VAL A 1 150 ? 215.107 210.282 277.563 1.00 50.75  ? 150 VAL A CB  1 
ATOM   1048  C  CG1 . VAL A 1 150 ? 215.519 209.100 278.407 1.00 50.75  ? 150 VAL A CG1 1 
ATOM   1049  C  CG2 . VAL A 1 150 ? 216.106 210.501 276.452 1.00 50.75  ? 150 VAL A CG2 1 
ATOM   1050  N  N   . ASP A 1 151 ? 212.824 207.797 277.049 1.00 49.94  ? 151 ASP A N   1 
ATOM   1051  C  CA  . ASP A 1 151 ? 212.740 206.428 276.559 1.00 49.94  ? 151 ASP A CA  1 
ATOM   1052  C  C   . ASP A 1 151 ? 211.425 206.100 275.869 1.00 49.94  ? 151 ASP A C   1 
ATOM   1053  O  O   . ASP A 1 151 ? 211.370 205.133 275.102 1.00 49.94  ? 151 ASP A O   1 
ATOM   1054  C  CB  . ASP A 1 151 ? 212.956 205.445 277.710 1.00 49.94  ? 151 ASP A CB  1 
ATOM   1055  C  CG  . ASP A 1 151 ? 214.420 205.174 277.972 1.00 49.94  ? 151 ASP A CG  1 
ATOM   1056  O  OD1 . ASP A 1 151 ? 215.176 204.996 276.996 1.00 49.94  ? 151 ASP A OD1 1 
ATOM   1057  O  OD2 . ASP A 1 151 ? 214.816 205.133 279.153 1.00 49.94  ? 151 ASP A OD2 1 
ATOM   1058  N  N   . HIS A 1 152 ? 210.367 206.868 276.116 1.00 51.52  ? 152 HIS A N   1 
ATOM   1059  C  CA  . HIS A 1 152 ? 209.048 206.464 275.638 1.00 51.52  ? 152 HIS A CA  1 
ATOM   1060  C  C   . HIS A 1 152 ? 208.928 206.528 274.116 1.00 51.52  ? 152 HIS A C   1 
ATOM   1061  O  O   . HIS A 1 152 ? 208.321 205.647 273.499 1.00 51.52  ? 152 HIS A O   1 
ATOM   1062  C  CB  . HIS A 1 152 ? 207.983 207.342 276.292 1.00 51.52  ? 152 HIS A CB  1 
ATOM   1063  C  CG  . HIS A 1 152 ? 206.597 207.083 275.796 1.00 51.52  ? 152 HIS A CG  1 
ATOM   1064  N  ND1 . HIS A 1 152 ? 205.765 208.090 275.362 1.00 51.52  ? 152 HIS A ND1 1 
ATOM   1065  C  CD2 . HIS A 1 152 ? 205.896 205.933 275.671 1.00 51.52  ? 152 HIS A CD2 1 
ATOM   1066  C  CE1 . HIS A 1 152 ? 204.610 207.571 274.986 1.00 51.52  ? 152 HIS A CE1 1 
ATOM   1067  N  NE2 . HIS A 1 152 ? 204.664 206.264 275.164 1.00 51.52  ? 152 HIS A NE2 1 
ATOM   1068  N  N   . LEU A 1 153 ? 209.500 207.557 273.492 1.00 50.11  ? 153 LEU A N   1 
ATOM   1069  C  CA  . LEU A 1 153 ? 209.054 207.971 272.164 1.00 50.11  ? 153 LEU A CA  1 
ATOM   1070  C  C   . LEU A 1 153 ? 209.615 207.142 271.019 1.00 50.11  ? 153 LEU A C   1 
ATOM   1071  O  O   . LEU A 1 153 ? 209.192 207.348 269.876 1.00 50.11  ? 153 LEU A O   1 
ATOM   1072  C  CB  . LEU A 1 153 ? 209.389 209.444 271.931 1.00 50.11  ? 153 LEU A CB  1 
ATOM   1073  C  CG  . LEU A 1 153 ? 208.299 210.417 272.368 1.00 50.11  ? 153 LEU A CG  1 
ATOM   1074  C  CD1 . LEU A 1 153 ? 207.087 210.223 271.489 1.00 50.11  ? 153 LEU A CD1 1 
ATOM   1075  C  CD2 . LEU A 1 153 ? 207.920 210.191 273.819 1.00 50.11  ? 153 LEU A CD2 1 
ATOM   1076  N  N   . ASP A 1 154 ? 210.553 206.234 271.278 1.00 48.28  ? 154 ASP A N   1 
ATOM   1077  C  CA  . ASP A 1 154 ? 211.108 205.370 270.234 1.00 48.28  ? 154 ASP A CA  1 
ATOM   1078  C  C   . ASP A 1 154 ? 211.807 206.183 269.141 1.00 48.28  ? 154 ASP A C   1 
ATOM   1079  O  O   . ASP A 1 154 ? 211.512 206.039 267.955 1.00 48.28  ? 154 ASP A O   1 
ATOM   1080  C  CB  . ASP A 1 154 ? 210.026 204.467 269.634 1.00 48.28  ? 154 ASP A CB  1 
ATOM   1081  C  CG  . ASP A 1 154 ? 210.598 203.345 268.792 1.00 48.28  ? 154 ASP A CG  1 
ATOM   1082  O  OD1 . ASP A 1 154 ? 211.192 202.407 269.364 1.00 48.28  ? 154 ASP A OD1 1 
ATOM   1083  O  OD2 . ASP A 1 154 ? 210.447 203.402 267.554 1.00 48.28  ? 154 ASP A OD2 1 
ATOM   1084  N  N   . ARG A 1 155 ? 212.738 207.044 269.543 1.00 46.68  ? 155 ARG A N   1 
ATOM   1085  C  CA  . ARG A 1 155 ? 213.557 207.820 268.621 1.00 46.68  ? 155 ARG A CA  1 
ATOM   1086  C  C   . ARG A 1 155 ? 215.006 207.773 269.088 1.00 46.68  ? 155 ARG A C   1 
ATOM   1087  O  O   . ARG A 1 155 ? 215.313 208.273 270.183 1.00 46.68  ? 155 ARG A O   1 
ATOM   1088  C  CB  . ARG A 1 155 ? 213.070 209.267 268.539 1.00 46.68  ? 155 ARG A CB  1 
ATOM   1089  C  CG  . ARG A 1 155 ? 211.772 209.454 267.775 1.00 46.68  ? 155 ARG A CG  1 
ATOM   1090  C  CD  . ARG A 1 155 ? 211.968 209.267 266.283 1.00 46.68  ? 155 ARG A CD  1 
ATOM   1091  N  NE  . ARG A 1 155 ? 213.100 210.031 265.773 1.00 46.68  ? 155 ARG A NE  1 
ATOM   1092  C  CZ  . ARG A 1 155 ? 213.099 211.344 265.587 1.00 46.68  ? 155 ARG A CZ  1 
ATOM   1093  N  NH1 . ARG A 1 155 ? 212.035 212.080 265.861 1.00 46.68  ? 155 ARG A NH1 1 
ATOM   1094  N  NH2 . ARG A 1 155 ? 214.192 211.932 265.111 1.00 46.68  ? 155 ARG A NH2 1 
ATOM   1095  N  N   . PRO A 1 156 ? 215.924 207.194 268.315 1.00 37.60  ? 156 PRO A N   1 
ATOM   1096  C  CA  . PRO A 1 156 ? 217.310 207.038 268.779 1.00 37.60  ? 156 PRO A CA  1 
ATOM   1097  C  C   . PRO A 1 156 ? 218.028 208.374 268.879 1.00 37.60  ? 156 PRO A C   1 
ATOM   1098  O  O   . PRO A 1 156 ? 218.263 209.045 267.869 1.00 37.60  ? 156 PRO A O   1 
ATOM   1099  C  CB  . PRO A 1 156 ? 217.939 206.144 267.707 1.00 37.60  ? 156 PRO A CB  1 
ATOM   1100  C  CG  . PRO A 1 156 ? 216.801 205.495 267.038 1.00 37.60  ? 156 PRO A CG  1 
ATOM   1101  C  CD  . PRO A 1 156 ? 215.689 206.477 267.058 1.00 37.60  ? 156 PRO A CD  1 
ATOM   1102  N  N   . VAL A 1 157 ? 218.399 208.745 270.103 1.00 34.92  ? 157 VAL A N   1 
ATOM   1103  C  CA  . VAL A 1 157 ? 219.183 209.940 270.371 1.00 34.92  ? 157 VAL A CA  1 
ATOM   1104  C  C   . VAL A 1 157 ? 220.384 209.551 271.217 1.00 34.92  ? 157 VAL A C   1 
ATOM   1105  O  O   . VAL A 1 157 ? 220.285 208.690 272.097 1.00 34.92  ? 157 VAL A O   1 
ATOM   1106  C  CB  . VAL A 1 157 ? 218.353 211.024 271.081 1.00 34.92  ? 157 VAL A CB  1 
ATOM   1107  C  CG1 . VAL A 1 157 ? 217.266 211.535 270.168 1.00 34.92  ? 157 VAL A CG1 1 
ATOM   1108  C  CG2 . VAL A 1 157 ? 217.754 210.477 272.349 1.00 34.92  ? 157 VAL A CG2 1 
ATOM   1109  N  N   . ILE A 1 158 ? 221.525 210.166 270.934 1.00 36.19  ? 158 ILE A N   1 
ATOM   1110  C  CA  . ILE A 1 158 ? 222.740 209.964 271.703 1.00 36.19  ? 158 ILE A CA  1 
ATOM   1111  C  C   . ILE A 1 158 ? 223.378 211.318 271.967 1.00 36.19  ? 158 ILE A C   1 
ATOM   1112  O  O   . ILE A 1 158 ? 223.166 212.283 271.225 1.00 36.19  ? 158 ILE A O   1 
ATOM   1113  C  CB  . ILE A 1 158 ? 223.733 209.031 270.983 1.00 36.19  ? 158 ILE A CB  1 
ATOM   1114  C  CG1 . ILE A 1 158 ? 224.112 209.608 269.625 1.00 36.19  ? 158 ILE A CG1 1 
ATOM   1115  C  CG2 . ILE A 1 158 ? 223.147 207.645 270.814 1.00 36.19  ? 158 ILE A CG2 1 
ATOM   1116  C  CD1 . ILE A 1 158 ? 225.250 208.879 268.948 1.00 36.19  ? 158 ILE A CD1 1 
ATOM   1117  N  N   . VAL A 1 159 ? 224.162 211.386 273.032 1.00 39.37  ? 159 VAL A N   1 
ATOM   1118  C  CA  . VAL A 1 159 ? 224.881 212.590 273.413 1.00 39.37  ? 159 VAL A CA  1 
ATOM   1119  C  C   . VAL A 1 159 ? 226.371 212.286 273.427 1.00 39.37  ? 159 VAL A C   1 
ATOM   1120  O  O   . VAL A 1 159 ? 226.806 211.244 273.930 1.00 39.37  ? 159 VAL A O   1 
ATOM   1121  C  CB  . VAL A 1 159 ? 224.404 213.099 274.782 1.00 39.37  ? 159 VAL A CB  1 
ATOM   1122  C  CG1 . VAL A 1 159 ? 225.211 214.299 275.215 1.00 39.37  ? 159 VAL A CG1 1 
ATOM   1123  C  CG2 . VAL A 1 159 ? 222.946 213.434 274.714 1.00 39.37  ? 159 VAL A CG2 1 
ATOM   1124  N  N   . LEU A 1 160 ? 227.161 213.201 272.864 1.00 46.25  ? 160 LEU A N   1 
ATOM   1125  C  CA  . LEU A 1 160 ? 228.589 213.007 272.677 1.00 46.25  ? 160 LEU A CA  1 
ATOM   1126  C  C   . LEU A 1 160 ? 229.363 214.145 273.319 1.00 46.25  ? 160 LEU A C   1 
ATOM   1127  O  O   . LEU A 1 160 ? 228.955 215.307 273.239 1.00 46.25  ? 160 LEU A O   1 
ATOM   1128  C  CB  . LEU A 1 160 ? 228.943 212.938 271.197 1.00 46.25  ? 160 LEU A CB  1 
ATOM   1129  C  CG  . LEU A 1 160 ? 228.047 212.127 270.261 1.00 46.25  ? 160 LEU A CG  1 
ATOM   1130  C  CD1 . LEU A 1 160 ? 228.690 212.048 268.895 1.00 46.25  ? 160 LEU A CD1 1 
ATOM   1131  C  CD2 . LEU A 1 160 ? 227.810 210.743 270.798 1.00 46.25  ? 160 LEU A CD2 1 
ATOM   1132  N  N   . ASP A 1 161 ? 230.493 213.800 273.936 1.00 58.75  ? 161 ASP A N   1 
ATOM   1133  C  CA  . ASP A 1 161 ? 231.366 214.771 274.572 1.00 58.75  ? 161 ASP A CA  1 
ATOM   1134  C  C   . ASP A 1 161 ? 232.130 215.553 273.503 1.00 58.75  ? 161 ASP A C   1 
ATOM   1135  O  O   . ASP A 1 161 ? 231.997 215.274 272.310 1.00 58.75  ? 161 ASP A O   1 
ATOM   1136  C  CB  . ASP A 1 161 ? 232.311 214.058 275.543 1.00 58.75  ? 161 ASP A CB  1 
ATOM   1137  C  CG  . ASP A 1 161 ? 233.258 213.102 274.849 1.00 58.75  ? 161 ASP A CG  1 
ATOM   1138  O  OD1 . ASP A 1 161 ? 233.098 212.868 273.635 1.00 58.75  ? 161 ASP A OD1 1 
ATOM   1139  O  OD2 . ASP A 1 161 ? 234.171 212.581 275.524 1.00 58.75  ? 161 ASP A OD2 1 
ATOM   1140  N  N   . PRO A 1 162 ? 232.924 216.561 273.895 1.00 59.71  ? 162 PRO A N   1 
ATOM   1141  C  CA  . PRO A 1 162 ? 233.718 217.276 272.881 1.00 59.71  ? 162 PRO A CA  1 
ATOM   1142  C  C   . PRO A 1 162 ? 234.624 216.373 272.063 1.00 59.71  ? 162 PRO A C   1 
ATOM   1143  O  O   . PRO A 1 162 ? 234.773 216.587 270.854 1.00 59.71  ? 162 PRO A O   1 
ATOM   1144  C  CB  . PRO A 1 162 ? 234.517 218.278 273.720 1.00 59.71  ? 162 PRO A CB  1 
ATOM   1145  C  CG  . PRO A 1 162 ? 233.628 218.568 274.863 1.00 59.71  ? 162 PRO A CG  1 
ATOM   1146  C  CD  . PRO A 1 162 ? 232.941 217.272 275.186 1.00 59.71  ? 162 PRO A CD  1 
ATOM   1147  N  N   . GLU A 1 163 ? 235.223 215.359 272.681 1.00 61.41  ? 163 GLU A N   1 
ATOM   1148  C  CA  . GLU A 1 163 ? 236.041 214.397 271.955 1.00 61.41  ? 163 GLU A CA  1 
ATOM   1149  C  C   . GLU A 1 163 ? 235.201 213.376 271.198 1.00 61.41  ? 163 GLU A C   1 
ATOM   1150  O  O   . GLU A 1 163 ? 235.753 212.403 270.675 1.00 61.41  ? 163 GLU A O   1 
ATOM   1151  C  CB  . GLU A 1 163 ? 236.991 213.689 272.924 1.00 61.41  ? 163 GLU A CB  1 
ATOM   1152  C  CG  . GLU A 1 163 ? 238.293 213.215 272.300 1.00 61.41  ? 163 GLU A CG  1 
ATOM   1153  C  CD  . GLU A 1 163 ? 239.259 212.657 273.326 1.00 61.41  ? 163 GLU A CD  1 
ATOM   1154  O  OE1 . GLU A 1 163 ? 238.899 212.611 274.521 1.00 61.41  ? 163 GLU A OE1 1 
ATOM   1155  O  OE2 . GLU A 1 163 ? 240.380 212.264 272.938 1.00 61.41  ? 163 GLU A OE2 1 
ATOM   1156  N  N   . ARG A 1 164 ? 233.883 213.578 271.144 1.00 59.73  ? 164 ARG A N   1 
ATOM   1157  C  CA  . ARG A 1 164 ? 232.946 212.765 270.371 1.00 59.73  ? 164 ARG A CA  1 
ATOM   1158  C  C   . ARG A 1 164 ? 232.821 211.339 270.901 1.00 59.73  ? 164 ARG A C   1 
ATOM   1159  O  O   . ARG A 1 164 ? 232.345 210.452 270.192 1.00 59.73  ? 164 ARG A O   1 
ATOM   1160  C  CB  . ARG A 1 164 ? 233.307 212.755 268.883 1.00 59.73  ? 164 ARG A CB  1 
ATOM   1161  C  CG  . ARG A 1 164 ? 233.648 214.127 268.330 1.00 59.73  ? 164 ARG A CG  1 
ATOM   1162  C  CD  . ARG A 1 164 ? 232.563 215.132 268.655 1.00 59.73  ? 164 ARG A CD  1 
ATOM   1163  N  NE  . ARG A 1 164 ? 233.078 216.493 268.737 1.00 59.73  ? 164 ARG A NE  1 
ATOM   1164  C  CZ  . ARG A 1 164 ? 233.142 217.331 267.712 1.00 59.73  ? 164 ARG A CZ  1 
ATOM   1165  N  NH1 . ARG A 1 164 ? 232.743 216.976 266.503 1.00 59.73  ? 164 ARG A NH1 1 
ATOM   1166  N  NH2 . ARG A 1 164 ? 233.617 218.557 267.906 1.00 59.73  ? 164 ARG A NH2 1 
ATOM   1167  N  N   . HIS A 1 165 ? 233.226 211.097 272.147 1.00 56.65  ? 165 HIS A N   1 
ATOM   1168  C  CA  . HIS A 1 165 ? 232.895 209.845 272.813 1.00 56.65  ? 165 HIS A CA  1 
ATOM   1169  C  C   . HIS A 1 165 ? 231.420 209.844 273.187 1.00 56.65  ? 165 HIS A C   1 
ATOM   1170  O  O   . HIS A 1 165 ? 230.875 210.864 273.618 1.00 56.65  ? 165 HIS A O   1 
ATOM   1171  C  CB  . HIS A 1 165 ? 233.741 209.650 274.070 1.00 56.65  ? 165 HIS A CB  1 
ATOM   1172  C  CG  . HIS A 1 165 ? 235.217 209.679 273.825 1.00 56.65  ? 165 HIS A CG  1 
ATOM   1173  N  ND1 . HIS A 1 165 ? 235.841 208.834 272.934 1.00 56.65  ? 165 HIS A ND1 1 
ATOM   1174  C  CD2 . HIS A 1 165 ? 236.193 210.443 274.366 1.00 56.65  ? 165 HIS A CD2 1 
ATOM   1175  C  CE1 . HIS A 1 165 ? 237.138 209.081 272.932 1.00 56.65  ? 165 HIS A CE1 1 
ATOM   1176  N  NE2 . HIS A 1 165 ? 237.378 210.054 273.793 1.00 56.65  ? 165 HIS A NE2 1 
ATOM   1177  N  N   . ILE A 1 166 ? 230.774 208.696 273.027 1.00 45.99  ? 166 ILE A N   1 
ATOM   1178  C  CA  . ILE A 1 166 ? 229.348 208.583 273.309 1.00 45.99  ? 166 ILE A CA  1 
ATOM   1179  C  C   . ILE A 1 166 ? 229.147 208.468 274.815 1.00 45.99  ? 166 ILE A C   1 
ATOM   1180  O  O   . ILE A 1 166 ? 229.919 207.796 275.509 1.00 45.99  ? 166 ILE A O   1 
ATOM   1181  C  CB  . ILE A 1 166 ? 228.739 207.396 272.548 1.00 45.99  ? 166 ILE A CB  1 
ATOM   1182  C  CG1 . ILE A 1 166 ? 227.242 207.585 272.365 1.00 45.99  ? 166 ILE A CG1 1 
ATOM   1183  C  CG2 . ILE A 1 166 ? 229.030 206.079 273.232 1.00 45.99  ? 166 ILE A CG2 1 
ATOM   1184  C  CD1 . ILE A 1 166 ? 226.622 206.526 271.504 1.00 45.99  ? 166 ILE A CD1 1 
ATOM   1185  N  N   . VAL A 1 167 ? 228.143 209.178 275.336 1.00 38.02  ? 167 VAL A N   1 
ATOM   1186  C  CA  . VAL A 1 167 ? 227.901 209.244 276.772 1.00 38.02  ? 167 VAL A CA  1 
ATOM   1187  C  C   . VAL A 1 167 ? 226.480 208.867 277.155 1.00 38.02  ? 167 VAL A C   1 
ATOM   1188  O  O   . VAL A 1 167 ? 226.260 208.392 278.268 1.00 38.02  ? 167 VAL A O   1 
ATOM   1189  C  CB  . VAL A 1 167 ? 228.246 210.638 277.327 1.00 38.02  ? 167 VAL A CB  1 
ATOM   1190  C  CG1 . VAL A 1 167 ? 228.229 210.632 278.840 1.00 38.02  ? 167 VAL A CG1 1 
ATOM   1191  C  CG2 . VAL A 1 167 ? 229.601 211.077 276.835 1.00 38.02  ? 167 VAL A CG2 1 
ATOM   1192  N  N   . GLN A 1 168 ? 225.506 209.033 276.270 1.00 40.74  ? 168 GLN A N   1 
ATOM   1193  C  CA  . GLN A 1 168 ? 224.144 208.645 276.600 1.00 40.74  ? 168 GLN A CA  1 
ATOM   1194  C  C   . GLN A 1 168 ? 223.530 207.949 275.395 1.00 40.74  ? 168 GLN A C   1 
ATOM   1195  O  O   . GLN A 1 168 ? 223.942 208.171 274.254 1.00 40.74  ? 168 GLN A O   1 
ATOM   1196  C  CB  . GLN A 1 168 ? 223.308 209.856 277.005 1.00 40.74  ? 168 GLN A CB  1 
ATOM   1197  C  CG  . GLN A 1 168 ? 222.088 209.524 277.817 1.00 40.74  ? 168 GLN A CG  1 
ATOM   1198  C  CD  . GLN A 1 168 ? 222.440 209.209 279.249 1.00 40.74  ? 168 GLN A CD  1 
ATOM   1199  O  OE1 . GLN A 1 168 ? 223.285 209.872 279.845 1.00 40.74  ? 168 GLN A OE1 1 
ATOM   1200  N  NE2 . GLN A 1 168 ? 221.797 208.196 279.812 1.00 40.74  ? 168 GLN A NE2 1 
ATOM   1201  N  N   . CYS A 1 169 ? 222.545 207.097 275.661 1.00 44.23  ? 169 CYS A N   1 
ATOM   1202  C  CA  . CYS A 1 169 ? 221.761 206.450 274.616 1.00 44.23  ? 169 CYS A CA  1 
ATOM   1203  C  C   . CYS A 1 169 ? 220.439 206.018 275.225 1.00 44.23  ? 169 CYS A C   1 
ATOM   1204  O  O   . CYS A 1 169 ? 220.327 205.907 276.447 1.00 44.23  ? 169 CYS A O   1 
ATOM   1205  C  CB  . CYS A 1 169 ? 222.490 205.246 274.028 1.00 44.23  ? 169 CYS A CB  1 
ATOM   1206  S  SG  . CYS A 1 169 ? 222.931 203.998 275.232 1.00 44.23  ? 169 CYS A SG  1 
ATOM   1207  N  N   . ASN A 1 170 ? 219.445 205.771 274.382 1.00 43.19  ? 170 ASN A N   1 
ATOM   1208  C  CA  . ASN A 1 170 ? 218.131 205.445 274.912 1.00 43.19  ? 170 ASN A CA  1 
ATOM   1209  C  C   . ASN A 1 170 ? 217.601 204.132 274.338 1.00 43.19  ? 170 ASN A C   1 
ATOM   1210  O  O   . ASN A 1 170 ? 218.292 203.405 273.610 1.00 43.19  ? 170 ASN A O   1 
ATOM   1211  C  CB  . ASN A 1 170 ? 217.148 206.596 274.677 1.00 43.19  ? 170 ASN A CB  1 
ATOM   1212  C  CG  . ASN A 1 170 ? 216.931 206.900 273.221 1.00 43.19  ? 170 ASN A CG  1 
ATOM   1213  O  OD1 . ASN A 1 170 ? 217.673 206.440 272.358 1.00 43.19  ? 170 ASN A OD1 1 
ATOM   1214  N  ND2 . ASN A 1 170 ? 215.906 207.695 272.937 1.00 43.19  ? 170 ASN A ND2 1 
ATOM   1215  N  N   . ARG A 1 171 ? 216.347 203.843 274.702 1.00 48.81  ? 171 ARG A N   1 
ATOM   1216  C  CA  . ARG A 1 171 ? 215.720 202.561 274.394 1.00 48.81  ? 171 ARG A CA  1 
ATOM   1217  C  C   . ARG A 1 171 ? 215.670 202.313 272.895 1.00 48.81  ? 171 ARG A C   1 
ATOM   1218  O  O   . ARG A 1 171 ? 215.967 201.209 272.426 1.00 48.81  ? 171 ARG A O   1 
ATOM   1219  C  CB  . ARG A 1 171 ? 214.310 202.527 274.988 1.00 48.81  ? 171 ARG A CB  1 
ATOM   1220  C  CG  . ARG A 1 171 ? 213.442 201.383 274.509 1.00 48.81  ? 171 ARG A CG  1 
ATOM   1221  C  CD  . ARG A 1 171 ? 213.916 200.068 275.096 1.00 48.81  ? 171 ARG A CD  1 
ATOM   1222  N  NE  . ARG A 1 171 ? 212.942 198.998 274.911 1.00 48.81  ? 171 ARG A NE  1 
ATOM   1223  C  CZ  . ARG A 1 171 ? 211.882 198.806 275.685 1.00 48.81  ? 171 ARG A CZ  1 
ATOM   1224  N  NH1 . ARG A 1 171 ? 211.627 199.595 276.716 1.00 48.81  ? 171 ARG A NH1 1 
ATOM   1225  N  NH2 . ARG A 1 171 ? 211.058 197.797 275.417 1.00 48.81  ? 171 ARG A NH2 1 
ATOM   1226  N  N   . ALA A 1 172 ? 215.283 203.329 272.126 1.00 45.26  ? 172 ALA A N   1 
ATOM   1227  C  CA  . ALA A 1 172 ? 215.227 203.160 270.682 1.00 45.26  ? 172 ALA A CA  1 
ATOM   1228  C  C   . ALA A 1 172 ? 216.598 202.829 270.120 1.00 45.26  ? 172 ALA A C   1 
ATOM   1229  O  O   . ALA A 1 172 ? 216.729 201.945 269.268 1.00 45.26  ? 172 ALA A O   1 
ATOM   1230  C  CB  . ALA A 1 172 ? 214.668 204.418 270.026 1.00 45.26  ? 172 ALA A CB  1 
ATOM   1231  N  N   . PHE A 1 173 ? 217.634 203.524 270.589 1.00 43.92  ? 173 PHE A N   1 
ATOM   1232  C  CA  . PHE A 1 173 ? 218.972 203.281 270.069 1.00 43.92  ? 173 PHE A CA  1 
ATOM   1233  C  C   . PHE A 1 173 ? 219.431 201.869 270.371 1.00 43.92  ? 173 PHE A C   1 
ATOM   1234  O  O   . PHE A 1 173 ? 219.975 201.184 269.498 1.00 43.92  ? 173 PHE A O   1 
ATOM   1235  C  CB  . PHE A 1 173 ? 219.964 204.277 270.644 1.00 43.92  ? 173 PHE A CB  1 
ATOM   1236  C  CG  . PHE A 1 173 ? 221.351 204.092 270.132 1.00 43.92  ? 173 PHE A CG  1 
ATOM   1237  C  CD1 . PHE A 1 173 ? 221.626 204.246 268.794 1.00 43.92  ? 173 PHE A CD1 1 
ATOM   1238  C  CD2 . PHE A 1 173 ? 222.381 203.776 270.982 1.00 43.92  ? 173 PHE A CD2 1 
ATOM   1239  C  CE1 . PHE A 1 173 ? 222.898 204.086 268.318 1.00 43.92  ? 173 PHE A CE1 1 
ATOM   1240  C  CE2 . PHE A 1 173 ? 223.654 203.622 270.510 1.00 43.92  ? 173 PHE A CE2 1 
ATOM   1241  C  CZ  . PHE A 1 173 ? 223.913 203.776 269.177 1.00 43.92  ? 173 PHE A CZ  1 
ATOM   1242  N  N   . THR A 1 174 ? 219.241 201.414 271.611 1.00 50.81  ? 174 THR A N   1 
ATOM   1243  C  CA  . THR A 1 174 ? 219.695 200.065 271.920 1.00 50.81  ? 174 THR A CA  1 
ATOM   1244  C  C   . THR A 1 174 ? 218.882 199.009 271.182 1.00 50.81  ? 174 THR A C   1 
ATOM   1245  O  O   . THR A 1 174 ? 219.466 198.042 270.684 1.00 50.81  ? 174 THR A O   1 
ATOM   1246  C  CB  . THR A 1 174 ? 219.687 199.810 273.430 1.00 50.81  ? 174 THR A CB  1 
ATOM   1247  O  OG1 . THR A 1 174 ? 220.291 198.540 273.699 1.00 50.81  ? 174 THR A OG1 1 
ATOM   1248  C  CG2 . THR A 1 174 ? 218.283 199.827 274.001 1.00 50.81  ? 174 THR A CG2 1 
ATOM   1249  N  N   . GLU A 1 175 ? 217.568 199.194 271.044 1.00 50.34  ? 175 GLU A N   1 
ATOM   1250  C  CA  . GLU A 1 175 ? 216.746 198.226 270.331 1.00 50.34  ? 175 GLU A CA  1 
ATOM   1251  C  C   . GLU A 1 175 ? 216.974 198.245 268.828 1.00 50.34  ? 175 GLU A C   1 
ATOM   1252  O  O   . GLU A 1 175 ? 216.653 197.263 268.151 1.00 50.34  ? 175 GLU A O   1 
ATOM   1253  C  CB  . GLU A 1 175 ? 215.265 198.471 270.620 1.00 50.34  ? 175 GLU A CB  1 
ATOM   1254  C  CG  . GLU A 1 175 ? 214.873 198.252 272.070 1.00 50.34  ? 175 GLU A CG  1 
ATOM   1255  C  CD  . GLU A 1 175 ? 214.537 196.806 272.378 1.00 50.34  ? 175 GLU A CD  1 
ATOM   1256  O  OE1 . GLU A 1 175 ? 214.900 195.922 271.574 1.00 50.34  ? 175 GLU A OE1 1 
ATOM   1257  O  OE2 . GLU A 1 175 ? 213.908 196.553 273.427 1.00 50.34  ? 175 GLU A OE2 1 
ATOM   1258  N  N   . MET A 1 176 ? 217.510 199.335 268.282 1.00 45.03  ? 176 MET A N   1 
ATOM   1259  C  CA  . MET A 1 176 ? 217.769 199.382 266.849 1.00 45.03  ? 176 MET A CA  1 
ATOM   1260  C  C   . MET A 1 176 ? 219.171 198.882 266.528 1.00 45.03  ? 176 MET A C   1 
ATOM   1261  O  O   . MET A 1 176 ? 219.347 197.982 265.700 1.00 45.03  ? 176 MET A O   1 
ATOM   1262  C  CB  . MET A 1 176 ? 217.572 200.804 266.328 1.00 45.03  ? 176 MET A CB  1 
ATOM   1263  C  CG  . MET A 1 176 ? 217.708 200.931 264.827 1.00 45.03  ? 176 MET A CG  1 
ATOM   1264  S  SD  . MET A 1 176 ? 217.116 202.511 264.213 1.00 45.03  ? 176 MET A SD  1 
ATOM   1265  C  CE  . MET A 1 176 ? 215.534 202.605 265.039 1.00 45.03  ? 176 MET A CE  1 
ATOM   1266  N  N   . PHE A 1 177 ? 220.185 199.450 267.177 1.00 49.26  ? 177 PHE A N   1 
ATOM   1267  C  CA  . PHE A 1 177 ? 221.574 199.141 266.877 1.00 49.26  ? 177 PHE A CA  1 
ATOM   1268  C  C   . PHE A 1 177 ? 222.180 198.135 267.843 1.00 49.26  ? 177 PHE A C   1 
ATOM   1269  O  O   . PHE A 1 177 ? 223.408 198.048 267.935 1.00 49.26  ? 177 PHE A O   1 
ATOM   1270  C  CB  . PHE A 1 177 ? 222.409 200.420 266.865 1.00 49.26  ? 177 PHE A CB  1 
ATOM   1271  C  CG  . PHE A 1 177 ? 222.151 201.296 265.684 1.00 49.26  ? 177 PHE A CG  1 
ATOM   1272  C  CD1 . PHE A 1 177 ? 220.953 201.964 265.550 1.00 49.26  ? 177 PHE A CD1 1 
ATOM   1273  C  CD2 . PHE A 1 177 ? 223.112 201.467 264.717 1.00 49.26  ? 177 PHE A CD2 1 
ATOM   1274  C  CE1 . PHE A 1 177 ? 220.714 202.767 264.469 1.00 49.26  ? 177 PHE A CE1 1 
ATOM   1275  C  CE2 . PHE A 1 177 ? 222.880 202.278 263.634 1.00 49.26  ? 177 PHE A CE2 1 
ATOM   1276  C  CZ  . PHE A 1 177 ? 221.678 202.925 263.511 1.00 49.26  ? 177 PHE A CZ  1 
ATOM   1277  N  N   . GLY A 1 178 ? 221.359 197.388 268.575 1.00 56.70  ? 178 GLY A N   1 
ATOM   1278  C  CA  . GLY A 1 178 ? 221.866 196.260 269.328 1.00 56.70  ? 178 GLY A CA  1 
ATOM   1279  C  C   . GLY A 1 178 ? 222.608 196.603 270.603 1.00 56.70  ? 178 GLY A C   1 
ATOM   1280  O  O   . GLY A 1 178 ? 222.293 196.064 271.668 1.00 56.70  ? 178 GLY A O   1 
ATOM   1281  N  N   . TYR A 1 179 ? 223.596 197.488 270.512 1.00 58.79  ? 179 TYR A N   1 
ATOM   1282  C  CA  . TYR A 1 179 ? 224.423 197.798 271.664 1.00 58.79  ? 179 TYR A CA  1 
ATOM   1283  C  C   . TYR A 1 179 ? 223.596 198.450 272.771 1.00 58.79  ? 179 TYR A C   1 
ATOM   1284  O  O   . TYR A 1 179 ? 222.679 199.233 272.526 1.00 58.79  ? 179 TYR A O   1 
ATOM   1285  C  CB  . TYR A 1 179 ? 225.572 198.717 271.261 1.00 58.79  ? 179 TYR A CB  1 
ATOM   1286  C  CG  . TYR A 1 179 ? 226.339 198.249 270.050 1.00 58.79  ? 179 TYR A CG  1 
ATOM   1287  C  CD1 . TYR A 1 179 ? 227.220 197.180 270.133 1.00 58.79  ? 179 TYR A CD1 1 
ATOM   1288  C  CD2 . TYR A 1 179 ? 226.192 198.880 268.828 1.00 58.79  ? 179 TYR A CD2 1 
ATOM   1289  C  CE1 . TYR A 1 179 ? 227.930 196.753 269.029 1.00 58.79  ? 179 TYR A CE1 1 
ATOM   1290  C  CE2 . TYR A 1 179 ? 226.895 198.460 267.719 1.00 58.79  ? 179 TYR A CE2 1 
ATOM   1291  C  CZ  . TYR A 1 179 ? 227.762 197.397 267.824 1.00 58.79  ? 179 TYR A CZ  1 
ATOM   1292  O  OH  . TYR A 1 179 ? 228.465 196.975 266.719 1.00 58.79  ? 179 TYR A OH  1 
ATOM   1293  N  N   . CYS A 1 180 ? 223.937 198.110 274.010 1.00 62.95  ? 180 CYS A N   1 
ATOM   1294  C  CA  . CYS A 1 180 ? 223.304 198.693 275.183 1.00 62.95  ? 180 CYS A CA  1 
ATOM   1295  C  C   . CYS A 1 180 ? 224.202 199.797 275.714 1.00 62.95  ? 180 CYS A C   1 
ATOM   1296  O  O   . CYS A 1 180 ? 225.270 200.063 275.164 1.00 62.95  ? 180 CYS A O   1 
ATOM   1297  C  CB  . CYS A 1 180 ? 223.044 197.643 276.271 1.00 62.95  ? 180 CYS A CB  1 
ATOM   1298  S  SG  . CYS A 1 180 ? 222.189 198.277 277.731 1.00 62.95  ? 180 CYS A SG  1 
ATOM   1299  N  N   . ILE A 1 181 ? 223.755 200.447 276.791 1.00 62.94  ? 181 ILE A N   1 
ATOM   1300  C  CA  . ILE A 1 181 ? 224.481 201.604 277.318 1.00 62.94  ? 181 ILE A CA  1 
ATOM   1301  C  C   . ILE A 1 181 ? 225.837 201.191 277.880 1.00 62.94  ? 181 ILE A C   1 
ATOM   1302  O  O   . ILE A 1 181 ? 226.857 201.850 277.638 1.00 62.94  ? 181 ILE A O   1 
ATOM   1303  C  CB  . ILE A 1 181 ? 223.631 202.342 278.368 1.00 62.94  ? 181 ILE A CB  1 
ATOM   1304  C  CG1 . ILE A 1 181 ? 224.449 203.449 279.041 1.00 62.94  ? 181 ILE A CG1 1 
ATOM   1305  C  CG2 . ILE A 1 181 ? 223.051 201.370 279.386 1.00 62.94  ? 181 ILE A CG2 1 
ATOM   1306  C  CD1 . ILE A 1 181 ? 224.882 204.554 278.111 1.00 62.94  ? 181 ILE A CD1 1 
ATOM   1307  N  N   . SER A 1 182 ? 225.868 200.098 278.646 1.00 62.93  ? 182 SER A N   1 
ATOM   1308  C  CA  . SER A 1 182 ? 227.106 199.691 279.303 1.00 62.93  ? 182 SER A CA  1 
ATOM   1309  C  C   . SER A 1 182 ? 228.192 199.385 278.282 1.00 62.93  ? 182 SER A C   1 
ATOM   1310  O  O   . SER A 1 182 ? 229.349 199.785 278.449 1.00 62.93  ? 182 SER A O   1 
ATOM   1311  C  CB  . SER A 1 182 ? 226.848 198.481 280.201 1.00 62.93  ? 182 SER A CB  1 
ATOM   1312  O  OG  . SER A 1 182 ? 226.278 197.413 279.465 1.00 62.93  ? 182 SER A OG  1 
ATOM   1313  N  N   . GLU A 1 183 ? 227.836 198.675 277.213 1.00 62.40  ? 183 GLU A N   1 
ATOM   1314  C  CA  . GLU A 1 183 ? 228.807 198.402 276.160 1.00 62.40  ? 183 GLU A CA  1 
ATOM   1315  C  C   . GLU A 1 183 ? 229.125 199.663 275.371 1.00 62.40  ? 183 GLU A C   1 
ATOM   1316  O  O   . GLU A 1 183 ? 230.294 199.960 275.104 1.00 62.40  ? 183 GLU A O   1 
ATOM   1317  C  CB  . GLU A 1 183 ? 228.280 197.311 275.232 1.00 62.40  ? 183 GLU A CB  1 
ATOM   1318  C  CG  . GLU A 1 183 ? 229.353 196.645 274.393 1.00 62.40  ? 183 GLU A CG  1 
ATOM   1319  C  CD  . GLU A 1 183 ? 229.535 197.314 273.048 1.00 62.40  ? 183 GLU A CD  1 
ATOM   1320  O  OE1 . GLU A 1 183 ? 228.681 198.146 272.679 1.00 62.40  ? 183 GLU A OE1 1 
ATOM   1321  O  OE2 . GLU A 1 183 ? 230.532 197.011 272.360 1.00 62.40  ? 183 GLU A OE2 1 
ATOM   1322  N  N   . ALA A 1 184 ? 228.098 200.411 274.978 1.00 62.72  ? 184 ALA A N   1 
ATOM   1323  C  CA  . ALA A 1 184 ? 228.250 201.643 274.203 1.00 62.72  ? 184 ALA A CA  1 
ATOM   1324  C  C   . ALA A 1 184 ? 228.293 202.874 275.099 1.00 62.72  ? 184 ALA A C   1 
ATOM   1325  O  O   . ALA A 1 184 ? 227.559 203.839 274.894 1.00 62.72  ? 184 ALA A O   1 
ATOM   1326  C  CB  . ALA A 1 184 ? 227.119 201.756 273.189 1.00 62.72  ? 184 ALA A CB  1 
ATOM   1327  N  N   . SER A 1 185 ? 229.144 202.844 276.117 1.00 61.26  ? 185 SER A N   1 
ATOM   1328  C  CA  . SER A 1 185 ? 229.364 203.990 276.987 1.00 61.26  ? 185 SER A CA  1 
ATOM   1329  C  C   . SER A 1 185 ? 230.856 204.262 277.080 1.00 61.26  ? 185 SER A C   1 
ATOM   1330  O  O   . SER A 1 185 ? 231.589 203.504 277.721 1.00 61.26  ? 185 SER A O   1 
ATOM   1331  C  CB  . SER A 1 185 ? 228.774 203.746 278.376 1.00 61.26  ? 185 SER A CB  1 
ATOM   1332  O  OG  . SER A 1 185 ? 229.171 204.761 279.279 1.00 61.26  ? 185 SER A OG  1 
ATOM   1333  N  N   . GLY A 1 186 ? 231.300 205.341 276.444 1.00 59.18  ? 186 GLY A N   1 
ATOM   1334  C  CA  . GLY A 1 186 ? 232.678 205.770 276.555 1.00 59.18  ? 186 GLY A CA  1 
ATOM   1335  C  C   . GLY A 1 186 ? 233.580 205.399 275.403 1.00 59.18  ? 186 GLY A C   1 
ATOM   1336  O  O   . GLY A 1 186 ? 234.730 205.013 275.640 1.00 59.18  ? 186 GLY A O   1 
ATOM   1337  N  N   . MET A 1 187 ? 233.107 205.504 274.163 1.00 61.34  ? 187 MET A N   1 
ATOM   1338  C  CA  . MET A 1 187 ? 233.927 205.200 273.000 1.00 61.34  ? 187 MET A CA  1 
ATOM   1339  C  C   . MET A 1 187 ? 233.377 205.928 271.781 1.00 61.34  ? 187 MET A C   1 
ATOM   1340  O  O   . MET A 1 187 ? 232.410 206.691 271.865 1.00 61.34  ? 187 MET A O   1 
ATOM   1341  C  CB  . MET A 1 187 ? 234.010 203.689 272.768 1.00 61.34  ? 187 MET A CB  1 
ATOM   1342  C  CG  . MET A 1 187 ? 232.690 203.048 272.422 1.00 61.34  ? 187 MET A CG  1 
ATOM   1343  S  SD  . MET A 1 187 ? 231.618 203.097 273.865 1.00 61.34  ? 187 MET A SD  1 
ATOM   1344  C  CE  . MET A 1 187 ? 232.557 202.051 274.976 1.00 61.34  ? 187 MET A CE  1 
ATOM   1345  N  N   . GLN A 1 188 ? 234.013 205.685 270.638 1.00 61.26  ? 188 GLN A N   1 
ATOM   1346  C  CA  . GLN A 1 188 ? 233.698 206.399 269.416 1.00 61.26  ? 188 GLN A CA  1 
ATOM   1347  C  C   . GLN A 1 188 ? 232.305 206.033 268.918 1.00 61.26  ? 188 GLN A C   1 
ATOM   1348  O  O   . GLN A 1 188 ? 231.815 204.928 269.159 1.00 61.26  ? 188 GLN A O   1 
ATOM   1349  C  CB  . GLN A 1 188 ? 234.736 206.086 268.341 1.00 61.26  ? 188 GLN A CB  1 
ATOM   1350  C  CG  . GLN A 1 188 ? 236.138 206.563 268.673 1.00 61.26  ? 188 GLN A CG  1 
ATOM   1351  C  CD  . GLN A 1 188 ? 236.209 208.064 268.863 1.00 61.26  ? 188 GLN A CD  1 
ATOM   1352  O  OE1 . GLN A 1 188 ? 236.244 208.557 269.990 1.00 61.26  ? 188 GLN A OE1 1 
ATOM   1353  N  NE2 . GLN A 1 188 ? 236.227 208.801 267.759 1.00 61.26  ? 188 GLN A NE2 1 
ATOM   1354  N  N   . PRO A 1 189 ? 231.645 206.951 268.215 1.00 60.69  ? 189 PRO A N   1 
ATOM   1355  C  CA  . PRO A 1 189 ? 230.291 206.694 267.705 1.00 60.69  ? 189 PRO A CA  1 
ATOM   1356  C  C   . PRO A 1 189 ? 230.243 206.175 266.277 1.00 60.69  ? 189 PRO A C   1 
ATOM   1357  O  O   . PRO A 1 189 ? 229.148 206.121 265.712 1.00 60.69  ? 189 PRO A O   1 
ATOM   1358  C  CB  . PRO A 1 189 ? 229.665 208.087 267.779 1.00 60.69  ? 189 PRO A CB  1 
ATOM   1359  C  CG  . PRO A 1 189 ? 230.812 208.997 267.456 1.00 60.69  ? 189 PRO A CG  1 
ATOM   1360  C  CD  . PRO A 1 189 ? 232.089 208.312 267.883 1.00 60.69  ? 189 PRO A CD  1 
ATOM   1361  N  N   . ASP A 1 190 ? 231.389 205.830 265.690 1.00 69.32  ? 190 ASP A N   1 
ATOM   1362  C  CA  . ASP A 1 190 ? 231.481 205.289 264.338 1.00 69.32  ? 190 ASP A CA  1 
ATOM   1363  C  C   . ASP A 1 190 ? 232.035 203.876 264.293 1.00 69.32  ? 190 ASP A C   1 
ATOM   1364  O  O   . ASP A 1 190 ? 231.666 203.105 263.409 1.00 69.32  ? 190 ASP A O   1 
ATOM   1365  C  CB  . ASP A 1 190 ? 232.352 206.195 263.462 1.00 69.32  ? 190 ASP A CB  1 
ATOM   1366  C  CG  . ASP A 1 190 ? 233.807 206.183 263.877 1.00 69.32  ? 190 ASP A CG  1 
ATOM   1367  O  OD1 . ASP A 1 190 ? 234.084 205.973 265.076 1.00 69.32  ? 190 ASP A OD1 1 
ATOM   1368  O  OD2 . ASP A 1 190 ? 234.676 206.386 263.006 1.00 69.32  ? 190 ASP A OD2 1 
ATOM   1369  N  N   . THR A 1 191 ? 232.925 203.516 265.219 1.00 67.33  ? 191 THR A N   1 
ATOM   1370  C  CA  . THR A 1 191 ? 233.378 202.132 265.293 1.00 67.33  ? 191 THR A CA  1 
ATOM   1371  C  C   . THR A 1 191 ? 232.202 201.205 265.564 1.00 67.33  ? 191 THR A C   1 
ATOM   1372  O  O   . THR A 1 191 ? 232.103 200.116 264.988 1.00 67.33  ? 191 THR A O   1 
ATOM   1373  C  CB  . THR A 1 191 ? 234.447 201.974 266.375 1.00 67.33  ? 191 THR A CB  1 
ATOM   1374  O  OG1 . THR A 1 191 ? 233.835 202.047 267.667 1.00 67.33  ? 191 THR A OG1 1 
ATOM   1375  C  CG2 . THR A 1 191 ? 235.496 203.067 266.258 1.00 67.33  ? 191 THR A CG2 1 
ATOM   1376  N  N   . LEU A 1 192 ? 231.294 201.631 266.441 1.00 65.05  ? 192 LEU A N   1 
ATOM   1377  C  CA  . LEU A 1 192 ? 230.065 200.886 266.665 1.00 65.05  ? 192 LEU A CA  1 
ATOM   1378  C  C   . LEU A 1 192 ? 229.095 201.029 265.506 1.00 65.05  ? 192 LEU A C   1 
ATOM   1379  O  O   . LEU A 1 192 ? 228.142 200.251 265.412 1.00 65.05  ? 192 LEU A O   1 
ATOM   1380  C  CB  . LEU A 1 192 ? 229.397 201.348 267.957 1.00 65.05  ? 192 LEU A CB  1 
ATOM   1381  C  CG  . LEU A 1 192 ? 229.909 200.715 269.248 1.00 65.05  ? 192 LEU A CG  1 
ATOM   1382  C  CD1 . LEU A 1 192 ? 231.278 201.249 269.627 1.00 65.05  ? 192 LEU A CD1 1 
ATOM   1383  C  CD2 . LEU A 1 192 ? 228.925 200.961 270.354 1.00 65.05  ? 192 LEU A CD2 1 
ATOM   1384  N  N   . LEU A 1 193 ? 229.308 202.007 264.633 1.00 70.96  ? 193 LEU A N   1 
ATOM   1385  C  CA  . LEU A 1 193 ? 228.487 202.202 263.445 1.00 70.96  ? 193 LEU A CA  1 
ATOM   1386  C  C   . LEU A 1 193 ? 229.297 201.939 262.180 1.00 70.96  ? 193 LEU A C   1 
ATOM   1387  O  O   . LEU A 1 193 ? 229.171 202.648 261.181 1.00 70.96  ? 193 LEU A O   1 
ATOM   1388  C  CB  . LEU A 1 193 ? 227.891 203.606 263.421 1.00 70.96  ? 193 LEU A CB  1 
ATOM   1389  C  CG  . LEU A 1 193 ? 227.098 204.025 264.659 1.00 70.96  ? 193 LEU A CG  1 
ATOM   1390  C  CD1 . LEU A 1 193 ? 226.280 205.275 264.372 1.00 70.96  ? 193 LEU A CD1 1 
ATOM   1391  C  CD2 . LEU A 1 193 ? 226.207 202.898 265.144 1.00 70.96  ? 193 LEU A CD2 1 
ATOM   1392  N  N   . ASN A 1 194 ? 230.167 200.933 262.232 1.00 75.98  ? 194 ASN A N   1 
ATOM   1393  C  CA  . ASN A 1 194 ? 230.973 200.577 261.073 1.00 75.98  ? 194 ASN A CA  1 
ATOM   1394  C  C   . ASN A 1 194 ? 230.099 200.210 259.878 1.00 75.98  ? 194 ASN A C   1 
ATOM   1395  O  O   . ASN A 1 194 ? 229.055 199.566 260.012 1.00 75.98  ? 194 ASN A O   1 
ATOM   1396  C  CB  . ASN A 1 194 ? 231.939 199.442 261.431 1.00 75.98  ? 194 ASN A CB  1 
ATOM   1397  C  CG  . ASN A 1 194 ? 231.237 198.184 261.920 1.00 75.98  ? 194 ASN A CG  1 
ATOM   1398  O  OD1 . ASN A 1 194 ? 230.013 198.082 261.906 1.00 75.98  ? 194 ASN A OD1 1 
ATOM   1399  N  ND2 . ASN A 1 194 ? 232.027 197.217 262.371 1.00 75.98  ? 194 ASN A ND2 1 
ATOM   1400  N  N   . THR A 1 195 ? 230.523 200.664 258.704 1.00 77.95  ? 195 THR A N   1 
ATOM   1401  C  CA  . THR A 1 195 ? 229.738 200.504 257.497 1.00 77.95  ? 195 THR A CA  1 
ATOM   1402  C  C   . THR A 1 195 ? 229.739 199.046 257.045 1.00 77.95  ? 195 THR A C   1 
ATOM   1403  O  O   . THR A 1 195 ? 230.645 198.281 257.381 1.00 77.95  ? 195 THR A O   1 
ATOM   1404  C  CB  . THR A 1 195 ? 230.296 201.393 256.391 1.00 77.95  ? 195 THR A CB  1 
ATOM   1405  O  OG1 . THR A 1 195 ? 231.595 200.922 256.012 1.00 77.95  ? 195 THR A OG1 1 
ATOM   1406  C  CG2 . THR A 1 195 ? 230.417 202.820 256.888 1.00 77.95  ? 195 THR A CG2 1 
ATOM   1407  N  N   . PRO A 1 196 ? 228.726 198.637 256.275 1.00 80.85  ? 196 PRO A N   1 
ATOM   1408  C  CA  . PRO A 1 196 ? 228.734 197.283 255.704 1.00 80.85  ? 196 PRO A CA  1 
ATOM   1409  C  C   . PRO A 1 196 ? 229.802 197.117 254.634 1.00 80.85  ? 196 PRO A C   1 
ATOM   1410  O  O   . PRO A 1 196 ? 230.629 198.011 254.425 1.00 80.85  ? 196 PRO A O   1 
ATOM   1411  C  CB  . PRO A 1 196 ? 227.323 197.136 255.121 1.00 80.85  ? 196 PRO A CB  1 
ATOM   1412  C  CG  . PRO A 1 196 ? 226.856 198.531 254.896 1.00 80.85  ? 196 PRO A CG  1 
ATOM   1413  C  CD  . PRO A 1 196 ? 227.464 199.343 255.998 1.00 80.85  ? 196 PRO A CD  1 
ATOM   1414  N  N   . GLU A 1 197 ? 229.791 195.970 253.950 1.00 84.48  ? 197 GLU A N   1 
ATOM   1415  C  CA  . GLU A 1 197 ? 230.860 195.634 253.015 1.00 84.48  ? 197 GLU A CA  1 
ATOM   1416  C  C   . GLU A 1 197 ? 230.954 196.605 251.844 1.00 84.48  ? 197 GLU A C   1 
ATOM   1417  O  O   . GLU A 1 197 ? 231.970 196.606 251.143 1.00 84.48  ? 197 GLU A O   1 
ATOM   1418  C  CB  . GLU A 1 197 ? 230.671 194.208 252.491 1.00 84.48  ? 197 GLU A CB  1 
ATOM   1419  C  CG  . GLU A 1 197 ? 229.583 194.065 251.438 1.00 84.48  ? 197 GLU A CG  1 
ATOM   1420  C  CD  . GLU A 1 197 ? 228.188 194.061 252.033 1.00 84.48  ? 197 GLU A CD  1 
ATOM   1421  O  OE1 . GLU A 1 197 ? 228.063 193.843 253.257 1.00 84.48  ? 197 GLU A OE1 1 
ATOM   1422  O  OE2 . GLU A 1 197 ? 227.218 194.277 251.277 1.00 84.48  ? 197 GLU A OE2 1 
ATOM   1423  N  N   . PHE A 1 198 ? 229.931 197.415 251.610 1.00 83.69  ? 198 PHE A N   1 
ATOM   1424  C  CA  . PHE A 1 198 ? 229.962 198.420 250.551 1.00 83.69  ? 198 PHE A CA  1 
ATOM   1425  C  C   . PHE A 1 198 ? 230.845 199.590 250.965 1.00 83.69  ? 198 PHE A C   1 
ATOM   1426  O  O   . PHE A 1 198 ? 230.429 200.391 251.812 1.00 83.69  ? 198 PHE A O   1 
ATOM   1427  C  CB  . PHE A 1 198 ? 228.546 198.898 250.247 1.00 83.69  ? 198 PHE A CB  1 
ATOM   1428  C  CG  . PHE A 1 198 ? 228.442 199.750 249.018 1.00 83.69  ? 198 PHE A CG  1 
ATOM   1429  C  CD1 . PHE A 1 198 ? 228.823 199.255 247.783 1.00 83.69  ? 198 PHE A CD1 1 
ATOM   1430  C  CD2 . PHE A 1 198 ? 227.938 201.037 249.093 1.00 83.69  ? 198 PHE A CD2 1 
ATOM   1431  C  CE1 . PHE A 1 198 ? 228.720 200.034 246.647 1.00 83.69  ? 198 PHE A CE1 1 
ATOM   1432  C  CE2 . PHE A 1 198 ? 227.829 201.819 247.960 1.00 83.69  ? 198 PHE A CE2 1 
ATOM   1433  C  CZ  . PHE A 1 198 ? 228.221 201.317 246.736 1.00 83.69  ? 198 PHE A CZ  1 
ATOM   1434  N  N   . PRO A 1 199 ? 232.046 199.733 250.410 1.00 83.78  ? 199 PRO A N   1 
ATOM   1435  C  CA  . PRO A 1 199 ? 233.008 200.723 250.914 1.00 83.78  ? 199 PRO A CA  1 
ATOM   1436  C  C   . PRO A 1 199 ? 232.997 202.068 250.202 1.00 83.78  ? 199 PRO A C   1 
ATOM   1437  O  O   . PRO A 1 199 ? 233.941 202.840 250.394 1.00 83.78  ? 199 PRO A O   1 
ATOM   1438  C  CB  . PRO A 1 199 ? 234.341 200.008 250.667 1.00 83.78  ? 199 PRO A CB  1 
ATOM   1439  C  CG  . PRO A 1 199 ? 234.101 199.283 249.361 1.00 83.78  ? 199 PRO A CG  1 
ATOM   1440  C  CD  . PRO A 1 199 ? 232.613 198.960 249.292 1.00 83.78  ? 199 PRO A CD  1 
ATOM   1441  N  N   . ALA A 1 200 ? 231.983 202.364 249.391 1.00 77.21  ? 200 ALA A N   1 
ATOM   1442  C  CA  . ALA A 1 200 ? 232.067 203.473 248.448 1.00 77.21  ? 200 ALA A CA  1 
ATOM   1443  C  C   . ALA A 1 200 ? 232.333 204.819 249.108 1.00 77.21  ? 200 ALA A C   1 
ATOM   1444  O  O   . ALA A 1 200 ? 233.413 205.392 248.933 1.00 77.21  ? 200 ALA A O   1 
ATOM   1445  C  CB  . ALA A 1 200 ? 230.783 203.564 247.623 1.00 77.21  ? 200 ALA A CB  1 
ATOM   1446  N  N   . ASP A 1 201 ? 231.373 205.335 249.873 1.00 73.65  ? 201 ASP A N   1 
ATOM   1447  C  CA  . ASP A 1 201 ? 231.501 206.709 250.341 1.00 73.65  ? 201 ASP A CA  1 
ATOM   1448  C  C   . ASP A 1 201 ? 231.127 206.868 251.811 1.00 73.65  ? 201 ASP A C   1 
ATOM   1449  O  O   . ASP A 1 201 ? 231.507 207.858 252.444 1.00 73.65  ? 201 ASP A O   1 
ATOM   1450  C  CB  . ASP A 1 201 ? 230.647 207.630 249.466 1.00 73.65  ? 201 ASP A CB  1 
ATOM   1451  C  CG  . ASP A 1 201 ? 231.041 209.088 249.593 1.00 73.65  ? 201 ASP A CG  1 
ATOM   1452  O  OD1 . ASP A 1 201 ? 232.112 209.461 249.070 1.00 73.65  ? 201 ASP A OD1 1 
ATOM   1453  O  OD2 . ASP A 1 201 ? 230.278 209.863 250.201 1.00 73.65  ? 201 ASP A OD2 1 
ATOM   1454  N  N   . ASN A 1 202 ? 230.380 205.909 252.364 1.00 72.50  ? 202 ASN A N   1 
ATOM   1455  C  CA  . ASN A 1 202 ? 229.922 206.049 253.742 1.00 72.50  ? 202 ASN A CA  1 
ATOM   1456  C  C   . ASN A 1 202 ? 231.086 206.082 254.717 1.00 72.50  ? 202 ASN A C   1 
ATOM   1457  O  O   . ASN A 1 202 ? 231.007 206.753 255.753 1.00 72.50  ? 202 ASN A O   1 
ATOM   1458  C  CB  . ASN A 1 202 ? 228.959 204.920 254.102 1.00 72.50  ? 202 ASN A CB  1 
ATOM   1459  C  CG  . ASN A 1 202 ? 229.474 203.560 253.693 1.00 72.50  ? 202 ASN A CG  1 
ATOM   1460  O  OD1 . ASN A 1 202 ? 230.681 203.344 253.592 1.00 72.50  ? 202 ASN A OD1 1 
ATOM   1461  N  ND2 . ASN A 1 202 ? 228.558 202.628 253.460 1.00 72.50  ? 202 ASN A ND2 1 
ATOM   1462  N  N   . ARG A 1 203 ? 232.178 205.389 254.392 1.00 76.15  ? 203 ARG A N   1 
ATOM   1463  C  CA  . ARG A 1 203 ? 233.330 205.350 255.282 1.00 76.15  ? 203 ARG A CA  1 
ATOM   1464  C  C   . ARG A 1 203 ? 233.918 206.731 255.530 1.00 76.15  ? 203 ARG A C   1 
ATOM   1465  O  O   . ARG A 1 203 ? 234.468 206.972 256.610 1.00 76.15  ? 203 ARG A O   1 
ATOM   1466  C  CB  . ARG A 1 203 ? 234.401 204.421 254.711 1.00 76.15  ? 203 ARG A CB  1 
ATOM   1467  C  CG  . ARG A 1 203 ? 235.560 204.140 255.654 1.00 76.15  ? 203 ARG A CG  1 
ATOM   1468  C  CD  . ARG A 1 203 ? 235.075 203.592 256.988 1.00 76.15  ? 203 ARG A CD  1 
ATOM   1469  N  NE  . ARG A 1 203 ? 235.047 204.615 258.026 1.00 76.15  ? 203 ARG A NE  1 
ATOM   1470  C  CZ  . ARG A 1 203 ? 234.770 204.381 259.302 1.00 76.15  ? 203 ARG A CZ  1 
ATOM   1471  N  NH1 . ARG A 1 203 ? 234.489 203.163 259.736 1.00 76.15  ? 203 ARG A NH1 1 
ATOM   1472  N  NH2 . ARG A 1 203 ? 234.774 205.394 260.164 1.00 76.15  ? 203 ARG A NH2 1 
ATOM   1473  N  N   . ILE A 1 204 ? 233.815 207.645 254.568 1.00 69.60  ? 204 ILE A N   1 
ATOM   1474  C  CA  . ILE A 1 204 ? 234.333 208.994 254.762 1.00 69.60  ? 204 ILE A CA  1 
ATOM   1475  C  C   . ILE A 1 204 ? 233.188 209.917 255.161 1.00 69.60  ? 204 ILE A C   1 
ATOM   1476  O  O   . ILE A 1 204 ? 233.393 210.903 255.879 1.00 69.60  ? 204 ILE A O   1 
ATOM   1477  C  CB  . ILE A 1 204 ? 235.064 209.504 253.505 1.00 69.60  ? 204 ILE A CB  1 
ATOM   1478  C  CG1 . ILE A 1 204 ? 235.768 210.832 253.794 1.00 69.60  ? 204 ILE A CG1 1 
ATOM   1479  C  CG2 . ILE A 1 204 ? 234.107 209.651 252.332 1.00 69.60  ? 204 ILE A CG2 1 
ATOM   1480  C  CD1 . ILE A 1 204 ? 236.837 210.737 254.861 1.00 69.60  ? 204 ILE A CD1 1 
ATOM   1481  N  N   . ARG A 1 205 ? 231.970 209.593 254.718 1.00 66.10  ? 205 ARG A N   1 
ATOM   1482  C  CA  . ARG A 1 205 ? 230.820 210.429 255.049 1.00 66.10  ? 205 ARG A CA  1 
ATOM   1483  C  C   . ARG A 1 205 ? 230.546 210.436 256.549 1.00 66.10  ? 205 ARG A C   1 
ATOM   1484  O  O   . ARG A 1 205 ? 230.291 211.496 257.134 1.00 66.10  ? 205 ARG A O   1 
ATOM   1485  C  CB  . ARG A 1 205 ? 229.591 209.956 254.277 1.00 66.10  ? 205 ARG A CB  1 
ATOM   1486  C  CG  . ARG A 1 205 ? 229.273 210.786 253.056 1.00 66.10  ? 205 ARG A CG  1 
ATOM   1487  C  CD  . ARG A 1 205 ? 227.994 210.314 252.406 1.00 66.10  ? 205 ARG A CD  1 
ATOM   1488  N  NE  . ARG A 1 205 ? 228.136 208.987 251.820 1.00 66.10  ? 205 ARG A NE  1 
ATOM   1489  C  CZ  . ARG A 1 205 ? 227.136 208.135 251.641 1.00 66.10  ? 205 ARG A CZ  1 
ATOM   1490  N  NH1 . ARG A 1 205 ? 225.897 208.439 251.990 1.00 66.10  ? 205 ARG A NH1 1 
ATOM   1491  N  NH2 . ARG A 1 205 ? 227.385 206.948 251.098 1.00 66.10  ? 205 ARG A NH2 1 
ATOM   1492  N  N   . LEU A 1 206 ? 230.591 209.267 257.190 1.00 65.34  ? 206 LEU A N   1 
ATOM   1493  C  CA  . LEU A 1 206 ? 230.499 209.213 258.644 1.00 65.34  ? 206 LEU A CA  1 
ATOM   1494  C  C   . LEU A 1 206 ? 231.589 210.074 259.263 1.00 65.34  ? 206 LEU A C   1 
ATOM   1495  O  O   . LEU A 1 206 ? 231.298 211.106 259.875 1.00 65.34  ? 206 LEU A O   1 
ATOM   1496  C  CB  . LEU A 1 206 ? 230.616 207.776 259.153 1.00 65.34  ? 206 LEU A CB  1 
ATOM   1497  C  CG  . LEU A 1 206 ? 229.342 206.949 259.291 1.00 65.34  ? 206 LEU A CG  1 
ATOM   1498  C  CD1 . LEU A 1 206 ? 229.681 205.474 259.357 1.00 65.34  ? 206 LEU A CD1 1 
ATOM   1499  C  CD2 . LEU A 1 206 ? 228.623 207.365 260.552 1.00 65.34  ? 206 LEU A CD2 1 
ATOM   1500  N  N   . GLN A 1 207 ? 232.850 209.694 259.042 1.00 66.66  ? 207 GLN A N   1 
ATOM   1501  C  CA  . GLN A 1 207 ? 233.983 210.396 259.636 1.00 66.66  ? 207 GLN A CA  1 
ATOM   1502  C  C   . GLN A 1 207 ? 233.895 211.907 259.459 1.00 66.66  ? 207 GLN A C   1 
ATOM   1503  O  O   . GLN A 1 207 ? 234.388 212.652 260.313 1.00 66.66  ? 207 GLN A O   1 
ATOM   1504  C  CB  . GLN A 1 207 ? 235.285 209.864 259.032 1.00 66.66  ? 207 GLN A CB  1 
ATOM   1505  C  CG  . GLN A 1 207 ? 236.551 210.539 259.537 1.00 66.66  ? 207 GLN A CG  1 
ATOM   1506  C  CD  . GLN A 1 207 ? 236.935 210.095 260.933 1.00 66.66  ? 207 GLN A CD  1 
ATOM   1507  O  OE1 . GLN A 1 207 ? 236.357 209.156 261.479 1.00 66.66  ? 207 GLN A OE1 1 
ATOM   1508  N  NE2 . GLN A 1 207 ? 237.918 210.768 261.518 1.00 66.66  ? 207 GLN A NE2 1 
ATOM   1509  N  N   . GLN A 1 208 ? 233.261 212.380 258.386 1.00 66.05  ? 208 GLN A N   1 
ATOM   1510  C  CA  . GLN A 1 208 ? 233.088 213.818 258.221 1.00 66.05  ? 208 GLN A CA  1 
ATOM   1511  C  C   . GLN A 1 208 ? 231.943 214.345 259.080 1.00 66.05  ? 208 GLN A C   1 
ATOM   1512  O  O   . GLN A 1 208 ? 232.111 215.324 259.819 1.00 66.05  ? 208 GLN A O   1 
ATOM   1513  C  CB  . GLN A 1 208 ? 232.848 214.151 256.748 1.00 66.05  ? 208 GLN A CB  1 
ATOM   1514  C  CG  . GLN A 1 208 ? 232.866 215.640 256.440 1.00 66.05  ? 208 GLN A CG  1 
ATOM   1515  C  CD  . GLN A 1 208 ? 232.860 215.930 254.952 1.00 66.05  ? 208 GLN A CD  1 
ATOM   1516  O  OE1 . GLN A 1 208 ? 231.997 216.652 254.452 1.00 66.05  ? 208 GLN A OE1 1 
ATOM   1517  N  NE2 . GLN A 1 208 ? 233.827 215.368 254.236 1.00 66.05  ? 208 GLN A NE2 1 
ATOM   1518  N  N   . LEU A 1 209 ? 230.773 213.707 258.993 1.00 56.34  ? 209 LEU A N   1 
ATOM   1519  C  CA  . LEU A 1 209 ? 229.597 214.209 259.698 1.00 56.34  ? 209 LEU A CA  1 
ATOM   1520  C  C   . LEU A 1 209 ? 229.804 214.190 261.205 1.00 56.34  ? 209 LEU A C   1 
ATOM   1521  O  O   . LEU A 1 209 ? 229.509 215.169 261.899 1.00 56.34  ? 209 LEU A O   1 
ATOM   1522  C  CB  . LEU A 1 209 ? 228.375 213.378 259.319 1.00 56.34  ? 209 LEU A CB  1 
ATOM   1523  C  CG  . LEU A 1 209 ? 227.094 213.818 260.005 1.00 56.34  ? 209 LEU A CG  1 
ATOM   1524  C  CD1 . LEU A 1 209 ? 226.739 215.192 259.519 1.00 56.34  ? 209 LEU A CD1 1 
ATOM   1525  C  CD2 . LEU A 1 209 ? 225.974 212.847 259.716 1.00 56.34  ? 209 LEU A CD2 1 
ATOM   1526  N  N   . LEU A 1 210 ? 230.327 213.094 261.722 1.00 60.02  ? 210 LEU A N   1 
ATOM   1527  C  CA  . LEU A 1 210 ? 230.563 212.883 263.143 1.00 60.02  ? 210 LEU A CA  1 
ATOM   1528  C  C   . LEU A 1 210 ? 231.653 213.748 263.686 1.00 60.02  ? 210 LEU A C   1 
ATOM   1529  O  O   . LEU A 1 210 ? 231.812 213.805 264.909 1.00 60.02  ? 210 LEU A O   1 
ATOM   1530  C  CB  . LEU A 1 210 ? 230.883 211.410 263.399 1.00 60.02  ? 210 LEU A CB  1 
ATOM   1531  C  CG  . LEU A 1 210 ? 229.695 210.475 263.628 1.00 60.02  ? 210 LEU A CG  1 
ATOM   1532  C  CD1 . LEU A 1 210 ? 228.789 210.413 262.411 1.00 60.02  ? 210 LEU A CD1 1 
ATOM   1533  C  CD2 . LEU A 1 210 ? 230.189 209.086 263.976 1.00 60.02  ? 210 LEU A CD2 1 
ATOM   1534  N  N   . TRP A 1 211 ? 232.408 214.426 262.823 1.00 61.14  ? 211 TRP A N   1 
ATOM   1535  C  CA  . TRP A 1 211 ? 233.474 215.319 263.255 1.00 61.14  ? 211 TRP A CA  1 
ATOM   1536  C  C   . TRP A 1 211 ? 233.244 216.760 262.821 1.00 61.14  ? 211 TRP A C   1 
ATOM   1537  O  O   . TRP A 1 211 ? 234.111 217.610 263.052 1.00 61.14  ? 211 TRP A O   1 
ATOM   1538  C  CB  . TRP A 1 211 ? 234.824 214.820 262.740 1.00 61.14  ? 211 TRP A CB  1 
ATOM   1539  C  CG  . TRP A 1 211 ? 235.567 214.072 263.780 1.00 61.14  ? 211 TRP A CG  1 
ATOM   1540  C  CD1 . TRP A 1 211 ? 235.754 212.726 263.842 1.00 61.14  ? 211 TRP A CD1 1 
ATOM   1541  C  CD2 . TRP A 1 211 ? 236.205 214.622 264.934 1.00 61.14  ? 211 TRP A CD2 1 
ATOM   1542  N  NE1 . TRP A 1 211 ? 236.481 212.402 264.961 1.00 61.14  ? 211 TRP A NE1 1 
ATOM   1543  C  CE2 . TRP A 1 211 ? 236.772 213.551 265.647 1.00 61.14  ? 211 TRP A CE2 1 
ATOM   1544  C  CE3 . TRP A 1 211 ? 236.358 215.918 265.429 1.00 61.14  ? 211 TRP A CE3 1 
ATOM   1545  C  CZ2 . TRP A 1 211 ? 237.479 213.736 266.829 1.00 61.14  ? 211 TRP A CZ2 1 
ATOM   1546  C  CZ3 . TRP A 1 211 ? 237.062 216.099 266.602 1.00 61.14  ? 211 TRP A CZ3 1 
ATOM   1547  C  CH2 . TRP A 1 211 ? 237.612 215.015 267.289 1.00 61.14  ? 211 TRP A CH2 1 
ATOM   1548  N  N   . LYS A 1 212 ? 232.100 217.059 262.209 1.00 55.64  ? 212 LYS A N   1 
ATOM   1549  C  CA  . LYS A 1 212 ? 231.772 218.433 261.863 1.00 55.64  ? 212 LYS A CA  1 
ATOM   1550  C  C   . LYS A 1 212 ? 231.628 219.283 263.123 1.00 55.64  ? 212 LYS A C   1 
ATOM   1551  O  O   . LYS A 1 212 ? 231.709 218.797 264.254 1.00 55.64  ? 212 LYS A O   1 
ATOM   1552  C  CB  . LYS A 1 212 ? 230.490 218.485 261.038 1.00 55.64  ? 212 LYS A CB  1 
ATOM   1553  C  CG  . LYS A 1 212 ? 230.700 218.169 259.576 1.00 55.64  ? 212 LYS A CG  1 
ATOM   1554  C  CD  . LYS A 1 212 ? 229.518 218.604 258.741 1.00 55.64  ? 212 LYS A CD  1 
ATOM   1555  C  CE  . LYS A 1 212 ? 229.797 219.908 258.011 1.00 55.64  ? 212 LYS A CE  1 
ATOM   1556  N  NZ  . LYS A 1 212 ? 228.709 220.248 257.052 1.00 55.64  ? 212 LYS A NZ  1 
ATOM   1557  N  N   . THR A 1 213 ? 231.413 220.583 262.920 1.00 50.47  ? 213 THR A N   1 
ATOM   1558  C  CA  . THR A 1 213 ? 231.211 221.511 264.026 1.00 50.47  ? 213 THR A CA  1 
ATOM   1559  C  C   . THR A 1 213 ? 230.032 222.440 263.734 1.00 50.47  ? 213 THR A C   1 
ATOM   1560  O  O   . THR A 1 213 ? 230.043 223.614 264.114 1.00 50.47  ? 213 THR A O   1 
ATOM   1561  C  CB  . THR A 1 213 ? 232.509 222.285 264.300 1.00 50.47  ? 213 THR A CB  1 
ATOM   1562  O  OG1 . THR A 1 213 ? 233.570 221.344 264.494 1.00 50.47  ? 213 THR A OG1 1 
ATOM   1563  C  CG2 . THR A 1 213 ? 232.420 223.093 265.594 1.00 50.47  ? 213 THR A CG2 1 
ATOM   1564  N  N   . ALA A 1 214 ? 229.013 221.936 263.048 1.00 42.84  ? 214 ALA A N   1 
ATOM   1565  C  CA  . ALA A 1 214 ? 227.816 222.707 262.766 1.00 42.84  ? 214 ALA A CA  1 
ATOM   1566  C  C   . ALA A 1 214 ? 226.678 221.736 262.511 1.00 42.84  ? 214 ALA A C   1 
ATOM   1567  O  O   . ALA A 1 214 ? 226.896 220.542 262.300 1.00 42.84  ? 214 ALA A O   1 
ATOM   1568  C  CB  . ALA A 1 214 ? 228.008 223.643 261.570 1.00 42.84  ? 214 ALA A CB  1 
ATOM   1569  N  N   . ARG A 1 215 ? 225.458 222.258 262.554 1.00 43.63  ? 215 ARG A N   1 
ATOM   1570  C  CA  . ARG A 1 215 ? 224.289 221.424 262.331 1.00 43.63  ? 215 ARG A CA  1 
ATOM   1571  C  C   . ARG A 1 215 ? 224.370 220.766 260.964 1.00 43.63  ? 215 ARG A C   1 
ATOM   1572  O  O   . ARG A 1 215 ? 224.619 221.433 259.959 1.00 43.63  ? 215 ARG A O   1 
ATOM   1573  C  CB  . ARG A 1 215 ? 223.022 222.268 262.429 1.00 43.63  ? 215 ARG A CB  1 
ATOM   1574  C  CG  . ARG A 1 215 ? 221.796 221.595 261.873 1.00 43.63  ? 215 ARG A CG  1 
ATOM   1575  C  CD  . ARG A 1 215 ? 220.570 222.424 262.146 1.00 43.63  ? 215 ARG A CD  1 
ATOM   1576  N  NE  . ARG A 1 215 ? 220.302 222.538 263.574 1.00 43.63  ? 215 ARG A NE  1 
ATOM   1577  C  CZ  . ARG A 1 215 ? 220.592 223.603 264.307 1.00 43.63  ? 215 ARG A CZ  1 
ATOM   1578  N  NH1 . ARG A 1 215 ? 221.176 224.666 263.779 1.00 43.63  ? 215 ARG A NH1 1 
ATOM   1579  N  NH2 . ARG A 1 215 ? 220.290 223.602 265.602 1.00 43.63  ? 215 ARG A NH2 1 
ATOM   1580  N  N   . ASP A 1 216 ? 224.161 219.454 260.921 1.00 46.71  ? 216 ASP A N   1 
ATOM   1581  C  CA  . ASP A 1 216 ? 224.229 218.773 259.632 1.00 46.71  ? 216 ASP A CA  1 
ATOM   1582  C  C   . ASP A 1 216 ? 223.470 217.458 259.698 1.00 46.71  ? 216 ASP A C   1 
ATOM   1583  O  O   . ASP A 1 216 ? 223.074 217.000 260.771 1.00 46.71  ? 216 ASP A O   1 
ATOM   1584  C  CB  . ASP A 1 216 ? 225.671 218.535 259.192 1.00 46.71  ? 216 ASP A CB  1 
ATOM   1585  C  CG  . ASP A 1 216 ? 225.785 218.276 257.701 1.00 46.71  ? 216 ASP A CG  1 
ATOM   1586  O  OD1 . ASP A 1 216 ? 224.739 218.286 257.019 1.00 46.71  ? 216 ASP A OD1 1 
ATOM   1587  O  OD2 . ASP A 1 216 ? 226.909 218.055 257.208 1.00 46.71  ? 216 ASP A OD2 1 
ATOM   1588  N  N   . GLN A 1 217 ? 223.261 216.861 258.526 1.00 48.35  ? 217 GLN A N   1 
ATOM   1589  C  CA  . GLN A 1 217 ? 222.521 215.613 258.429 1.00 48.35  ? 217 GLN A CA  1 
ATOM   1590  C  C   . GLN A 1 217 ? 222.854 214.924 257.115 1.00 48.35  ? 217 GLN A C   1 
ATOM   1591  O  O   . GLN A 1 217 ? 223.047 215.578 256.088 1.00 48.35  ? 217 GLN A O   1 
ATOM   1592  C  CB  . GLN A 1 217 ? 221.015 215.852 258.539 1.00 48.35  ? 217 GLN A CB  1 
ATOM   1593  C  CG  . GLN A 1 217 ? 220.492 216.928 257.614 1.00 48.35  ? 217 GLN A CG  1 
ATOM   1594  C  CD  . GLN A 1 217 ? 218.983 217.024 257.636 1.00 48.35  ? 217 GLN A CD  1 
ATOM   1595  O  OE1 . GLN A 1 217 ? 218.323 216.382 258.450 1.00 48.35  ? 217 GLN A OE1 1 
ATOM   1596  N  NE2 . GLN A 1 217 ? 218.427 217.826 256.737 1.00 48.35  ? 217 GLN A NE2 1 
ATOM   1597  N  N   . ASP A 1 218 ? 222.914 213.597 257.162 1.00 50.01  ? 218 ASP A N   1 
ATOM   1598  C  CA  . ASP A 1 218 ? 223.210 212.798 255.976 1.00 50.01  ? 218 ASP A CA  1 
ATOM   1599  C  C   . ASP A 1 218 ? 222.422 211.495 256.045 1.00 50.01  ? 218 ASP A C   1 
ATOM   1600  O  O   . ASP A 1 218 ? 221.692 211.240 257.008 1.00 50.01  ? 218 ASP A O   1 
ATOM   1601  C  CB  . ASP A 1 218 ? 224.714 212.532 255.852 1.00 50.01  ? 218 ASP A CB  1 
ATOM   1602  C  CG  . ASP A 1 218 ? 225.507 213.783 255.548 1.00 50.01  ? 218 ASP A CG  1 
ATOM   1603  O  OD1 . ASP A 1 218 ? 225.746 214.583 256.476 1.00 50.01  ? 218 ASP A OD1 1 
ATOM   1604  O  OD2 . ASP A 1 218 ? 225.893 213.970 254.375 1.00 50.01  ? 218 ASP A OD2 1 
ATOM   1605  N  N   . GLU A 1 219 ? 222.568 210.669 255.011 1.00 53.16  ? 219 GLU A N   1 
ATOM   1606  C  CA  . GLU A 1 219 ? 222.013 209.323 254.984 1.00 53.16  ? 219 GLU A CA  1 
ATOM   1607  C  C   . GLU A 1 219 ? 223.150 208.325 254.859 1.00 53.16  ? 219 GLU A C   1 
ATOM   1608  O  O   . GLU A 1 219 ? 224.008 208.467 253.984 1.00 53.16  ? 219 GLU A O   1 
ATOM   1609  C  CB  . GLU A 1 219 ? 221.034 209.137 253.828 1.00 53.16  ? 219 GLU A CB  1 
ATOM   1610  C  CG  . GLU A 1 219 ? 219.739 209.884 253.984 1.00 53.16  ? 219 GLU A CG  1 
ATOM   1611  C  CD  . GLU A 1 219 ? 219.589 210.978 252.963 1.00 53.16  ? 219 GLU A CD  1 
ATOM   1612  O  OE1 . GLU A 1 219 ? 220.617 211.563 252.567 1.00 53.16  ? 219 GLU A OE1 1 
ATOM   1613  O  OE2 . GLU A 1 219 ? 218.444 211.255 252.552 1.00 53.16  ? 219 GLU A OE2 1 
ATOM   1614  N  N   . PHE A 1 220 ? 223.148 207.311 255.720 1.00 58.89  ? 220 PHE A N   1 
ATOM   1615  C  CA  . PHE A 1 220 ? 224.215 206.326 255.762 1.00 58.89  ? 220 PHE A CA  1 
ATOM   1616  C  C   . PHE A 1 220 ? 223.658 204.916 255.652 1.00 58.89  ? 220 PHE A C   1 
ATOM   1617  O  O   . PHE A 1 220 ? 222.572 204.614 256.164 1.00 58.89  ? 220 PHE A O   1 
ATOM   1618  C  CB  . PHE A 1 220 ? 225.022 206.421 257.052 1.00 58.89  ? 220 PHE A CB  1 
ATOM   1619  C  CG  . PHE A 1 220 ? 225.695 207.731 257.251 1.00 58.89  ? 220 PHE A CG  1 
ATOM   1620  C  CD1 . PHE A 1 220 ? 226.176 208.448 256.179 1.00 58.89  ? 220 PHE A CD1 1 
ATOM   1621  C  CD2 . PHE A 1 220 ? 225.872 208.234 258.520 1.00 58.89  ? 220 PHE A CD2 1 
ATOM   1622  C  CE1 . PHE A 1 220 ? 226.802 209.656 256.369 1.00 58.89  ? 220 PHE A CE1 1 
ATOM   1623  C  CE2 . PHE A 1 220 ? 226.495 209.436 258.717 1.00 58.89  ? 220 PHE A CE2 1 
ATOM   1624  C  CZ  . PHE A 1 220 ? 226.965 210.149 257.641 1.00 58.89  ? 220 PHE A CZ  1 
ATOM   1625  N  N   . LEU A 1 221 ? 224.424 204.059 254.980 1.00 64.42  ? 221 LEU A N   1 
ATOM   1626  C  CA  . LEU A 1 221 ? 224.220 202.622 255.066 1.00 64.42  ? 221 LEU A CA  1 
ATOM   1627  C  C   . LEU A 1 221 ? 224.927 202.099 256.305 1.00 64.42  ? 221 LEU A C   1 
ATOM   1628  O  O   . LEU A 1 221 ? 226.142 202.251 256.446 1.00 64.42  ? 221 LEU A O   1 
ATOM   1629  C  CB  . LEU A 1 221 ? 224.796 201.918 253.839 1.00 64.42  ? 221 LEU A CB  1 
ATOM   1630  C  CG  . LEU A 1 221 ? 224.301 202.242 252.434 1.00 64.42  ? 221 LEU A CG  1 
ATOM   1631  C  CD1 . LEU A 1 221 ? 225.042 203.456 251.886 1.00 64.42  ? 221 LEU A CD1 1 
ATOM   1632  C  CD2 . LEU A 1 221 ? 224.464 201.044 251.512 1.00 64.42  ? 221 LEU A CD2 1 
ATOM   1633  N  N   . LEU A 1 222 ? 224.178 201.479 257.208 1.00 64.49  ? 222 LEU A N   1 
ATOM   1634  C  CA  . LEU A 1 222 ? 224.826 200.973 258.406 1.00 64.49  ? 222 LEU A CA  1 
ATOM   1635  C  C   . LEU A 1 222 ? 224.398 199.540 258.662 1.00 64.49  ? 222 LEU A C   1 
ATOM   1636  O  O   . LEU A 1 222 ? 223.280 199.137 258.333 1.00 64.49  ? 222 LEU A O   1 
ATOM   1637  C  CB  . LEU A 1 222 ? 224.538 201.835 259.639 1.00 64.49  ? 222 LEU A CB  1 
ATOM   1638  C  CG  . LEU A 1 222 ? 225.138 203.237 259.623 1.00 64.49  ? 222 LEU A CG  1 
ATOM   1639  C  CD1 . LEU A 1 222 ? 224.792 203.971 260.897 1.00 64.49  ? 222 LEU A CD1 1 
ATOM   1640  C  CD2 . LEU A 1 222 ? 226.637 203.174 259.435 1.00 64.49  ? 222 LEU A CD2 1 
ATOM   1641  N  N   . LEU A 1 223 ? 225.314 198.784 259.263 1.00 73.91  ? 223 LEU A N   1 
ATOM   1642  C  CA  . LEU A 1 223 ? 225.130 197.368 259.551 1.00 73.91  ? 223 LEU A CA  1 
ATOM   1643  C  C   . LEU A 1 223 ? 224.865 197.218 261.043 1.00 73.91  ? 223 LEU A C   1 
ATOM   1644  O  O   . LEU A 1 223 ? 225.688 197.625 261.868 1.00 73.91  ? 223 LEU A O   1 
ATOM   1645  C  CB  . LEU A 1 223 ? 226.365 196.575 259.132 1.00 73.91  ? 223 LEU A CB  1 
ATOM   1646  C  CG  . LEU A 1 223 ? 226.267 195.049 259.094 1.00 73.91  ? 223 LEU A CG  1 
ATOM   1647  C  CD1 . LEU A 1 223 ? 225.443 194.600 257.899 1.00 73.91  ? 223 LEU A CD1 1 
ATOM   1648  C  CD2 . LEU A 1 223 ? 227.651 194.421 259.061 1.00 73.91  ? 223 LEU A CD2 1 
ATOM   1649  N  N   . THR A 1 224 ? 223.722 196.630 261.386 1.00 72.45  ? 224 THR A N   1 
ATOM   1650  C  CA  . THR A 1 224 ? 223.396 196.389 262.780 1.00 72.45  ? 224 THR A CA  1 
ATOM   1651  C  C   . THR A 1 224 ? 224.380 195.392 263.388 1.00 72.45  ? 224 THR A C   1 
ATOM   1652  O  O   . THR A 1 224 ? 225.151 194.729 262.691 1.00 72.45  ? 224 THR A O   1 
ATOM   1653  C  CB  . THR A 1 224 ? 221.970 195.864 262.917 1.00 72.45  ? 224 THR A CB  1 
ATOM   1654  O  OG1 . THR A 1 224 ? 221.888 194.552 262.352 1.00 72.45  ? 224 THR A OG1 1 
ATOM   1655  C  CG2 . THR A 1 224 ? 221.002 196.769 262.194 1.00 72.45  ? 224 THR A CG2 1 
ATOM   1656  N  N   . ARG A 1 225 ? 224.349 195.298 264.718 1.00 69.04  ? 225 ARG A N   1 
ATOM   1657  C  CA  . ARG A 1 225 ? 225.234 194.366 265.410 1.00 69.04  ? 225 ARG A CA  1 
ATOM   1658  C  C   . ARG A 1 225 ? 224.921 192.921 265.039 1.00 69.04  ? 225 ARG A C   1 
ATOM   1659  O  O   . ARG A 1 225 ? 225.835 192.112 264.839 1.00 69.04  ? 225 ARG A O   1 
ATOM   1660  C  CB  . ARG A 1 225 ? 225.131 194.562 266.919 1.00 69.04  ? 225 ARG A CB  1 
ATOM   1661  C  CG  . ARG A 1 225 ? 226.232 193.873 267.694 1.00 69.04  ? 225 ARG A CG  1 
ATOM   1662  C  CD  . ARG A 1 225 ? 225.899 193.808 269.169 1.00 69.04  ? 225 ARG A CD  1 
ATOM   1663  N  NE  . ARG A 1 225 ? 224.790 192.902 269.431 1.00 69.04  ? 225 ARG A NE  1 
ATOM   1664  C  CZ  . ARG A 1 225 ? 224.343 192.598 270.641 1.00 69.04  ? 225 ARG A CZ  1 
ATOM   1665  N  NH1 . ARG A 1 225 ? 224.893 193.111 271.730 1.00 69.04  ? 225 ARG A NH1 1 
ATOM   1666  N  NH2 . ARG A 1 225 ? 223.320 191.757 270.763 1.00 69.04  ? 225 ARG A NH2 1 
ATOM   1667  N  N   . THR A 1 226 ? 223.635 192.575 264.945 1.00 77.04  ? 226 THR A N   1 
ATOM   1668  C  CA  . THR A 1 226 ? 223.250 191.218 264.575 1.00 77.04  ? 226 THR A CA  1 
ATOM   1669  C  C   . THR A 1 226 ? 223.560 190.891 263.121 1.00 77.04  ? 226 THR A C   1 
ATOM   1670  O  O   . THR A 1 226 ? 223.587 189.709 262.765 1.00 77.04  ? 226 THR A O   1 
ATOM   1671  C  CB  . THR A 1 226 ? 221.760 190.996 264.844 1.00 77.04  ? 226 THR A CB  1 
ATOM   1672  O  OG1 . THR A 1 226 ? 220.998 192.023 264.199 1.00 77.04  ? 226 THR A OG1 1 
ATOM   1673  C  CG2 . THR A 1 226 ? 221.479 191.024 266.338 1.00 77.04  ? 226 THR A CG2 1 
ATOM   1674  N  N   . GLY A 1 227 ? 223.792 191.896 262.278 1.00 74.96  ? 227 GLY A N   1 
ATOM   1675  C  CA  . GLY A 1 227 ? 224.227 191.675 260.914 1.00 74.96  ? 227 GLY A CA  1 
ATOM   1676  C  C   . GLY A 1 227 ? 223.279 192.152 259.837 1.00 74.96  ? 227 GLY A C   1 
ATOM   1677  O  O   . GLY A 1 227 ? 223.609 192.021 258.652 1.00 74.96  ? 227 GLY A O   1 
ATOM   1678  N  N   . GLU A 1 228 ? 222.120 192.696 260.191 1.00 75.73  ? 228 GLU A N   1 
ATOM   1679  C  CA  . GLU A 1 228 ? 221.207 193.197 259.179 1.00 75.73  ? 228 GLU A CA  1 
ATOM   1680  C  C   . GLU A 1 228 ? 221.700 194.536 258.639 1.00 75.73  ? 228 GLU A C   1 
ATOM   1681  O  O   . GLU A 1 228 ? 222.583 195.178 259.210 1.00 75.73  ? 228 GLU A O   1 
ATOM   1682  C  CB  . GLU A 1 228 ? 219.795 193.344 259.744 1.00 75.73  ? 228 GLU A CB  1 
ATOM   1683  C  CG  . GLU A 1 228 ? 219.128 192.028 260.106 1.00 75.73  ? 228 GLU A CG  1 
ATOM   1684  C  CD  . GLU A 1 228 ? 219.519 191.540 261.486 1.00 75.73  ? 228 GLU A CD  1 
ATOM   1685  O  OE1 . GLU A 1 228 ? 219.909 192.379 262.322 1.00 75.73  ? 228 GLU A OE1 1 
ATOM   1686  O  OE2 . GLU A 1 228 ? 219.436 190.319 261.736 1.00 75.73  ? 228 GLU A OE2 1 
ATOM   1687  N  N   . LYS A 1 229 ? 221.116 194.953 257.521 1.00 73.58  ? 229 LYS A N   1 
ATOM   1688  C  CA  . LYS A 1 229 ? 221.466 196.209 256.873 1.00 73.58  ? 229 LYS A CA  1 
ATOM   1689  C  C   . LYS A 1 229 ? 220.328 197.204 257.042 1.00 73.58  ? 229 LYS A C   1 
ATOM   1690  O  O   . LYS A 1 229 ? 219.171 196.885 256.749 1.00 73.58  ? 229 LYS A O   1 
ATOM   1691  C  CB  . LYS A 1 229 ? 221.765 195.996 255.388 1.00 73.58  ? 229 LYS A CB  1 
ATOM   1692  C  CG  . LYS A 1 229 ? 223.089 195.308 255.120 1.00 73.58  ? 229 LYS A CG  1 
ATOM   1693  C  CD  . LYS A 1 229 ? 223.319 195.112 253.631 1.00 73.58  ? 229 LYS A CD  1 
ATOM   1694  C  CE  . LYS A 1 229 ? 224.642 194.412 253.367 1.00 73.58  ? 229 LYS A CE  1 
ATOM   1695  N  NZ  . LYS A 1 229 ? 224.856 194.154 251.917 1.00 73.58  ? 229 LYS A NZ  1 
ATOM   1696  N  N   . ILE A 1 230 ? 220.658 198.405 257.515 1.00 66.68  ? 230 ILE A N   1 
ATOM   1697  C  CA  . ILE A 1 230 ? 219.687 199.479 257.686 1.00 66.68  ? 230 ILE A CA  1 
ATOM   1698  C  C   . ILE A 1 230 ? 220.212 200.739 257.014 1.00 66.68  ? 230 ILE A C   1 
ATOM   1699  O  O   . ILE A 1 230 ? 221.380 201.110 257.184 1.00 66.68  ? 230 ILE A O   1 
ATOM   1700  C  CB  . ILE A 1 230 ? 219.375 199.753 259.173 1.00 66.68  ? 230 ILE A CB  1 
ATOM   1701  C  CG1 . ILE A 1 230 ? 220.661 199.797 259.993 1.00 66.68  ? 230 ILE A CG1 1 
ATOM   1702  C  CG2 . ILE A 1 230 ? 218.427 198.707 259.721 1.00 66.68  ? 230 ILE A CG2 1 
ATOM   1703  C  CD1 . ILE A 1 230 ? 220.453 200.266 261.414 1.00 66.68  ? 230 ILE A CD1 1 
ATOM   1704  N  N   . TRP A 1 231 ? 219.351 201.377 256.229 1.00 57.83  ? 231 TRP A N   1 
ATOM   1705  C  CA  . TRP A 1 231 ? 219.587 202.720 255.723 1.00 57.83  ? 231 TRP A CA  1 
ATOM   1706  C  C   . TRP A 1 231 ? 218.985 203.712 256.706 1.00 57.83  ? 231 TRP A C   1 
ATOM   1707  O  O   . TRP A 1 231 ? 217.772 203.693 256.936 1.00 57.83  ? 231 TRP A O   1 
ATOM   1708  C  CB  . TRP A 1 231 ? 218.933 202.891 254.357 1.00 57.83  ? 231 TRP A CB  1 
ATOM   1709  C  CG  . TRP A 1 231 ? 219.827 202.751 253.193 1.00 57.83  ? 231 TRP A CG  1 
ATOM   1710  C  CD1 . TRP A 1 231 ? 220.145 201.606 252.545 1.00 57.83  ? 231 TRP A CD1 1 
ATOM   1711  C  CD2 . TRP A 1 231 ? 220.477 203.809 252.485 1.00 57.83  ? 231 TRP A CD2 1 
ATOM   1712  N  NE1 . TRP A 1 231 ? 220.977 201.875 251.490 1.00 57.83  ? 231 TRP A NE1 1 
ATOM   1713  C  CE2 . TRP A 1 231 ? 221.192 203.225 251.431 1.00 57.83  ? 231 TRP A CE2 1 
ATOM   1714  C  CE3 . TRP A 1 231 ? 220.531 205.195 252.650 1.00 57.83  ? 231 TRP A CE3 1 
ATOM   1715  C  CZ2 . TRP A 1 231 ? 221.953 203.972 250.541 1.00 57.83  ? 231 TRP A CZ2 1 
ATOM   1716  C  CZ3 . TRP A 1 231 ? 221.291 205.938 251.767 1.00 57.83  ? 231 TRP A CZ3 1 
ATOM   1717  C  CH2 . TRP A 1 231 ? 221.993 205.324 250.727 1.00 57.83  ? 231 TRP A CH2 1 
ATOM   1718  N  N   . ILE A 1 232 ? 219.818 204.575 257.293 1.00 50.15  ? 232 ILE A N   1 
ATOM   1719  C  CA  . ILE A 1 232 ? 219.333 205.493 258.319 1.00 50.15  ? 232 ILE A CA  1 
ATOM   1720  C  C   . ILE A 1 232 ? 219.761 206.915 257.993 1.00 50.15  ? 232 ILE A C   1 
ATOM   1721  O  O   . ILE A 1 232 ? 220.684 207.151 257.213 1.00 50.15  ? 232 ILE A O   1 
ATOM   1722  C  CB  . ILE A 1 232 ? 219.810 205.109 259.732 1.00 50.15  ? 232 ILE A CB  1 
ATOM   1723  C  CG1 . ILE A 1 232 ? 221.302 205.340 259.864 1.00 50.15  ? 232 ILE A CG1 1 
ATOM   1724  C  CG2 . ILE A 1 232 ? 219.479 203.667 260.041 1.00 50.15  ? 232 ILE A CG2 1 
ATOM   1725  C  CD1 . ILE A 1 232 ? 221.716 205.574 261.277 1.00 50.15  ? 232 ILE A CD1 1 
ATOM   1726  N  N   . LYS A 1 233 ? 219.047 207.871 258.581 1.00 45.46  ? 233 LYS A N   1 
ATOM   1727  C  CA  . LYS A 1 233 ? 219.303 209.297 258.389 1.00 45.46  ? 233 LYS A CA  1 
ATOM   1728  C  C   . LYS A 1 233 ? 219.784 209.867 259.716 1.00 45.46  ? 233 LYS A C   1 
ATOM   1729  O  O   . LYS A 1 233 ? 219.074 209.799 260.722 1.00 45.46  ? 233 LYS A O   1 
ATOM   1730  C  CB  . LYS A 1 233 ? 218.054 210.018 257.900 1.00 45.46  ? 233 LYS A CB  1 
ATOM   1731  C  CG  . LYS A 1 233 ? 218.234 211.510 257.721 1.00 45.46  ? 233 LYS A CG  1 
ATOM   1732  C  CD  . LYS A 1 233 ? 217.074 212.117 256.953 1.00 45.46  ? 233 LYS A CD  1 
ATOM   1733  C  CE  . LYS A 1 233 ? 215.865 212.316 257.839 1.00 45.46  ? 233 LYS A CE  1 
ATOM   1734  N  NZ  . LYS A 1 233 ? 215.904 213.632 258.518 1.00 45.46  ? 233 LYS A NZ  1 
ATOM   1735  N  N   . ALA A 1 234 ? 220.979 210.436 259.716 1.00 39.71  ? 234 ALA A N   1 
ATOM   1736  C  CA  . ALA A 1 234 ? 221.617 210.875 260.945 1.00 39.71  ? 234 ALA A CA  1 
ATOM   1737  C  C   . ALA A 1 234 ? 221.781 212.384 260.949 1.00 39.71  ? 234 ALA A C   1 
ATOM   1738  O  O   . ALA A 1 234 ? 222.230 212.974 259.961 1.00 39.71  ? 234 ALA A O   1 
ATOM   1739  C  CB  . ALA A 1 234 ? 222.980 210.209 261.108 1.00 39.71  ? 234 ALA A CB  1 
ATOM   1740  N  N   . SER A 1 235 ? 221.424 213.003 262.069 1.00 39.30  ? 235 SER A N   1 
ATOM   1741  C  CA  . SER A 1 235 ? 221.558 214.438 262.246 1.00 39.30  ? 235 SER A CA  1 
ATOM   1742  C  C   . SER A 1 235 ? 222.418 214.721 263.463 1.00 39.30  ? 235 SER A C   1 
ATOM   1743  O  O   . SER A 1 235 ? 222.294 214.050 264.489 1.00 39.30  ? 235 SER A O   1 
ATOM   1744  C  CB  . SER A 1 235 ? 220.201 215.108 262.409 1.00 39.30  ? 235 SER A CB  1 
ATOM   1745  O  OG  . SER A 1 235 ? 220.349 216.431 262.889 1.00 39.30  ? 235 SER A OG  1 
ATOM   1746  N  N   . ILE A 1 236 ? 223.284 215.719 263.342 1.00 38.63  ? 236 ILE A N   1 
ATOM   1747  C  CA  . ILE A 1 236 ? 224.200 216.107 264.402 1.00 38.63  ? 236 ILE A CA  1 
ATOM   1748  C  C   . ILE A 1 236 ? 224.031 217.596 264.650 1.00 38.63  ? 236 ILE A C   1 
ATOM   1749  O  O   . ILE A 1 236 ? 223.905 218.378 263.697 1.00 38.63  ? 236 ILE A O   1 
ATOM   1750  C  CB  . ILE A 1 236 ? 225.659 215.765 264.051 1.00 38.63  ? 236 ILE A CB  1 
ATOM   1751  C  CG1 . ILE A 1 236 ? 226.576 216.103 265.216 1.00 38.63  ? 236 ILE A CG1 1 
ATOM   1752  C  CG2 . ILE A 1 236 ? 226.107 216.494 262.808 1.00 38.63  ? 236 ILE A CG2 1 
ATOM   1753  C  CD1 . ILE A 1 236 ? 227.966 215.561 265.051 1.00 38.63  ? 236 ILE A CD1 1 
ATOM   1754  N  N   . SER A 1 237 ? 223.994 217.984 265.929 1.00 37.28  ? 237 SER A N   1 
ATOM   1755  C  CA  . SER A 1 237 ? 223.834 219.381 266.282 1.00 37.28  ? 237 SER A CA  1 
ATOM   1756  C  C   . SER A 1 237 ? 224.524 219.666 267.603 1.00 37.28  ? 237 SER A C   1 
ATOM   1757  O  O   . SER A 1 237 ? 224.402 218.868 268.544 1.00 37.28  ? 237 SER A O   1 
ATOM   1758  C  CB  . SER A 1 237 ? 222.357 219.771 266.378 1.00 37.28  ? 237 SER A CB  1 
ATOM   1759  O  OG  . SER A 1 237 ? 221.740 219.145 267.485 1.00 37.28  ? 237 SER A OG  1 
ATOM   1760  N  N   . PRO A 1 238 ? 225.248 220.773 267.707 1.00 37.23  ? 238 PRO A N   1 
ATOM   1761  C  CA  . PRO A 1 238 ? 225.955 221.091 268.943 1.00 37.23  ? 238 PRO A CA  1 
ATOM   1762  C  C   . PRO A 1 238 ? 225.157 221.988 269.873 1.00 37.23  ? 238 PRO A C   1 
ATOM   1763  O  O   . PRO A 1 238 ? 224.310 222.777 269.455 1.00 37.23  ? 238 PRO A O   1 
ATOM   1764  C  CB  . PRO A 1 238 ? 227.201 221.818 268.428 1.00 37.23  ? 238 PRO A CB  1 
ATOM   1765  C  CG  . PRO A 1 238 ? 226.707 222.541 267.236 1.00 37.23  ? 238 PRO A CG  1 
ATOM   1766  C  CD  . PRO A 1 238 ? 225.618 221.691 266.620 1.00 37.23  ? 238 PRO A CD  1 
ATOM   1767  N  N   . VAL A 1 239 ? 225.453 221.851 271.161 1.00 44.94  ? 239 VAL A N   1 
ATOM   1768  C  CA  . VAL A 1 239 ? 224.886 222.685 272.210 1.00 44.94  ? 239 VAL A CA  1 
ATOM   1769  C  C   . VAL A 1 239 ? 226.025 223.309 273.001 1.00 44.94  ? 239 VAL A C   1 
ATOM   1770  O  O   . VAL A 1 239 ? 226.971 222.613 273.402 1.00 44.94  ? 239 VAL A O   1 
ATOM   1771  C  CB  . VAL A 1 239 ? 223.941 221.894 273.127 1.00 44.94  ? 239 VAL A CB  1 
ATOM   1772  C  CG1 . VAL A 1 239 ? 222.676 221.545 272.382 1.00 44.94  ? 239 VAL A CG1 1 
ATOM   1773  C  CG2 . VAL A 1 239 ? 224.615 220.633 273.614 1.00 44.94  ? 239 VAL A CG2 1 
ATOM   1774  N  N   . TYR A 1 240 ? 225.920 224.620 273.224 1.00 52.93  ? 240 TYR A N   1 
ATOM   1775  C  CA  . TYR A 1 240 ? 226.971 225.452 273.789 1.00 52.93  ? 240 TYR A CA  1 
ATOM   1776  C  C   . TYR A 1 240 ? 226.587 225.925 275.183 1.00 52.93  ? 240 TYR A C   1 
ATOM   1777  O  O   . TYR A 1 240 ? 225.415 226.199 275.456 1.00 52.93  ? 240 TYR A O   1 
ATOM   1778  C  CB  . TYR A 1 240 ? 227.229 226.677 272.912 1.00 52.93  ? 240 TYR A CB  1 
ATOM   1779  C  CG  . TYR A 1 240 ? 227.719 226.374 271.519 1.00 52.93  ? 240 TYR A CG  1 
ATOM   1780  C  CD1 . TYR A 1 240 ? 228.977 225.836 271.308 1.00 52.93  ? 240 TYR A CD1 1 
ATOM   1781  C  CD2 . TYR A 1 240 ? 226.929 226.645 270.413 1.00 52.93  ? 240 TYR A CD2 1 
ATOM   1782  C  CE1 . TYR A 1 240 ? 229.433 225.564 270.037 1.00 52.93  ? 240 TYR A CE1 1 
ATOM   1783  C  CE2 . TYR A 1 240 ? 227.377 226.379 269.137 1.00 52.93  ? 240 TYR A CE2 1 
ATOM   1784  C  CZ  . TYR A 1 240 ? 228.630 225.838 268.955 1.00 52.93  ? 240 TYR A CZ  1 
ATOM   1785  O  OH  . TYR A 1 240 ? 229.083 225.567 267.686 1.00 52.93  ? 240 TYR A OH  1 
ATOM   1786  N  N   . ASP A 1 241 ? 227.587 226.044 276.052 1.00 64.89  ? 241 ASP A N   1 
ATOM   1787  C  CA  . ASP A 1 241 ? 227.380 226.534 277.405 1.00 64.89  ? 241 ASP A CA  1 
ATOM   1788  C  C   . ASP A 1 241 ? 227.295 228.060 277.404 1.00 64.89  ? 241 ASP A C   1 
ATOM   1789  O  O   . ASP A 1 241 ? 227.180 228.707 276.359 1.00 64.89  ? 241 ASP A O   1 
ATOM   1790  C  CB  . ASP A 1 241 ? 228.503 226.045 278.318 1.00 64.89  ? 241 ASP A CB  1 
ATOM   1791  C  CG  . ASP A 1 241 ? 228.085 225.968 279.775 1.00 64.89  ? 241 ASP A CG  1 
ATOM   1792  O  OD1 . ASP A 1 241 ? 226.867 226.017 280.049 1.00 64.89  ? 241 ASP A OD1 1 
ATOM   1793  O  OD2 . ASP A 1 241 ? 228.975 225.859 280.645 1.00 64.89  ? 241 ASP A OD2 1 
ATOM   1794  N  N   . VAL A 1 242 ? 227.348 228.644 278.603 1.00 66.37  ? 242 VAL A N   1 
ATOM   1795  C  CA  . VAL A 1 242 ? 227.278 230.097 278.731 1.00 66.37  ? 242 VAL A CA  1 
ATOM   1796  C  C   . VAL A 1 242 ? 228.538 230.745 278.170 1.00 66.37  ? 242 VAL A C   1 
ATOM   1797  O  O   . VAL A 1 242 ? 228.479 231.800 277.527 1.00 66.37  ? 242 VAL A O   1 
ATOM   1798  C  CB  . VAL A 1 242 ? 227.044 230.490 280.201 1.00 66.37  ? 242 VAL A CB  1 
ATOM   1799  C  CG1 . VAL A 1 242 ? 227.007 232.004 280.353 1.00 66.37  ? 242 VAL A CG1 1 
ATOM   1800  C  CG2 . VAL A 1 242 ? 225.758 229.865 280.718 1.00 66.37  ? 242 VAL A CG2 1 
ATOM   1801  N  N   . LEU A 1 243 ? 229.691 230.118 278.385 1.00 68.07  ? 243 LEU A N   1 
ATOM   1802  C  CA  . LEU A 1 243 ? 230.973 230.661 277.958 1.00 68.07  ? 243 LEU A CA  1 
ATOM   1803  C  C   . LEU A 1 243 ? 231.236 230.468 276.469 1.00 68.07  ? 243 LEU A C   1 
ATOM   1804  O  O   . LEU A 1 243 ? 232.393 230.565 276.043 1.00 68.07  ? 243 LEU A O   1 
ATOM   1805  C  CB  . LEU A 1 243 ? 232.109 230.034 278.772 1.00 68.07  ? 243 LEU A CB  1 
ATOM   1806  C  CG  . LEU A 1 243 ? 232.577 230.791 280.018 1.00 68.07  ? 243 LEU A CG  1 
ATOM   1807  C  CD1 . LEU A 1 243 ? 233.193 232.128 279.634 1.00 68.07  ? 243 LEU A CD1 1 
ATOM   1808  C  CD2 . LEU A 1 243 ? 231.442 230.984 281.014 1.00 68.07  ? 243 LEU A CD2 1 
ATOM   1809  N  N   . ALA A 1 244 ? 230.201 230.170 275.685 1.00 63.66  ? 244 ALA A N   1 
ATOM   1810  C  CA  . ALA A 1 244 ? 230.259 230.022 274.234 1.00 63.66  ? 244 ALA A CA  1 
ATOM   1811  C  C   . ALA A 1 244 ? 231.174 228.893 273.783 1.00 63.66  ? 244 ALA A C   1 
ATOM   1812  O  O   . ALA A 1 244 ? 231.469 228.789 272.587 1.00 63.66  ? 244 ALA A O   1 
ATOM   1813  C  CB  . ALA A 1 244 ? 230.685 231.323 273.545 1.00 63.66  ? 244 ALA A CB  1 
ATOM   1814  N  N   . HIS A 1 245 ? 231.633 228.045 274.696 1.00 64.95  ? 245 HIS A N   1 
ATOM   1815  C  CA  . HIS A 1 245 ? 232.440 226.896 274.321 1.00 64.95  ? 245 HIS A CA  1 
ATOM   1816  C  C   . HIS A 1 245 ? 231.551 225.752 273.849 1.00 64.95  ? 245 HIS A C   1 
ATOM   1817  O  O   . HIS A 1 245 ? 230.373 225.661 274.208 1.00 64.95  ? 245 HIS A O   1 
ATOM   1818  C  CB  . HIS A 1 245 ? 233.301 226.437 275.496 1.00 64.95  ? 245 HIS A CB  1 
ATOM   1819  C  CG  . HIS A 1 245 ? 234.329 227.439 275.917 1.00 64.95  ? 245 HIS A CG  1 
ATOM   1820  N  ND1 . HIS A 1 245 ? 234.332 228.024 277.165 1.00 64.95  ? 245 HIS A ND1 1 
ATOM   1821  C  CD2 . HIS A 1 245 ? 235.390 227.959 275.255 1.00 64.95  ? 245 HIS A CD2 1 
ATOM   1822  C  CE1 . HIS A 1 245 ? 235.349 228.861 277.254 1.00 64.95  ? 245 HIS A CE1 1 
ATOM   1823  N  NE2 . HIS A 1 245 ? 236.007 228.841 276.109 1.00 64.95  ? 245 HIS A NE2 1 
ATOM   1824  N  N   . LEU A 1 246 ? 232.126 224.875 273.031 1.00 57.37  ? 246 LEU A N   1 
ATOM   1825  C  CA  . LEU A 1 246 ? 231.403 223.704 272.547 1.00 57.37  ? 246 LEU A CA  1 
ATOM   1826  C  C   . LEU A 1 246 ? 231.275 222.700 273.681 1.00 57.37  ? 246 LEU A C   1 
ATOM   1827  O  O   . LEU A 1 246 ? 232.268 222.098 274.101 1.00 57.37  ? 246 LEU A O   1 
ATOM   1828  C  CB  . LEU A 1 246 ? 232.125 223.090 271.355 1.00 57.37  ? 246 LEU A CB  1 
ATOM   1829  C  CG  . LEU A 1 246 ? 231.587 221.734 270.913 1.00 57.37  ? 246 LEU A CG  1 
ATOM   1830  C  CD1 . LEU A 1 246 ? 230.174 221.895 270.403 1.00 57.37  ? 246 LEU A CD1 1 
ATOM   1831  C  CD2 . LEU A 1 246 ? 232.474 221.120 269.849 1.00 57.37  ? 246 LEU A CD2 1 
ATOM   1832  N  N   . GLN A 1 247 ? 230.055 222.511 274.181 1.00 56.49  ? 247 GLN A N   1 
ATOM   1833  C  CA  . GLN A 1 247 ? 229.839 221.663 275.346 1.00 56.49  ? 247 GLN A CA  1 
ATOM   1834  C  C   . GLN A 1 247 ? 229.407 220.246 274.995 1.00 56.49  ? 247 GLN A C   1 
ATOM   1835  O  O   . GLN A 1 247 ? 229.984 219.291 275.522 1.00 56.49  ? 247 GLN A O   1 
ATOM   1836  C  CB  . GLN A 1 247 ? 228.809 222.294 276.285 1.00 56.49  ? 247 GLN A CB  1 
ATOM   1837  C  CG  . GLN A 1 247 ? 229.083 221.999 277.746 1.00 56.49  ? 247 GLN A CG  1 
ATOM   1838  C  CD  . GLN A 1 247 ? 228.027 222.565 278.666 1.00 56.49  ? 247 GLN A CD  1 
ATOM   1839  O  OE1 . GLN A 1 247 ? 226.866 222.708 278.284 1.00 56.49  ? 247 GLN A OE1 1 
ATOM   1840  N  NE2 . GLN A 1 247 ? 228.421 222.881 279.893 1.00 56.49  ? 247 GLN A NE2 1 
ATOM   1841  N  N   . ASN A 1 248 ? 228.414 220.064 274.124 1.00 47.56  ? 248 ASN A N   1 
ATOM   1842  C  CA  . ASN A 1 248 ? 228.003 218.701 273.806 1.00 47.56  ? 248 ASN A CA  1 
ATOM   1843  C  C   . ASN A 1 248 ? 227.506 218.626 272.373 1.00 47.56  ? 248 ASN A C   1 
ATOM   1844  O  O   . ASN A 1 248 ? 227.191 219.642 271.754 1.00 47.56  ? 248 ASN A O   1 
ATOM   1845  C  CB  . ASN A 1 248 ? 226.932 218.201 274.775 1.00 47.56  ? 248 ASN A CB  1 
ATOM   1846  C  CG  . ASN A 1 248 ? 227.520 217.469 275.957 1.00 47.56  ? 248 ASN A CG  1 
ATOM   1847  O  OD1 . ASN A 1 248 ? 228.346 216.576 275.796 1.00 47.56  ? 248 ASN A OD1 1 
ATOM   1848  N  ND2 . ASN A 1 248 ? 227.097 217.844 277.156 1.00 47.56  ? 248 ASN A ND2 1 
ATOM   1849  N  N   . LEU A 1 249 ? 227.445 217.406 271.844 1.00 43.63  ? 249 LEU A N   1 
ATOM   1850  C  CA  . LEU A 1 249 ? 226.959 217.162 270.490 1.00 43.63  ? 249 LEU A CA  1 
ATOM   1851  C  C   . LEU A 1 249 ? 225.856 216.117 270.550 1.00 43.63  ? 249 LEU A C   1 
ATOM   1852  O  O   . LEU A 1 249 ? 226.122 214.953 270.856 1.00 43.63  ? 249 LEU A O   1 
ATOM   1853  C  CB  . LEU A 1 249 ? 228.089 216.692 269.581 1.00 43.63  ? 249 LEU A CB  1 
ATOM   1854  C  CG  . LEU A 1 249 ? 229.064 217.724 269.025 1.00 43.63  ? 249 LEU A CG  1 
ATOM   1855  C  CD1 . LEU A 1 249 ? 230.109 218.112 270.056 1.00 43.63  ? 249 LEU A CD1 1 
ATOM   1856  C  CD2 . LEU A 1 249 ? 229.712 217.183 267.774 1.00 43.63  ? 249 LEU A CD2 1 
ATOM   1857  N  N   . VAL A 1 250 ? 224.636 216.509 270.265 1.00 36.77  ? 250 VAL A N   1 
ATOM   1858  C  CA  . VAL A 1 250 ? 223.548 215.545 270.248 1.00 36.77  ? 250 VAL A CA  1 
ATOM   1859  C  C   . VAL A 1 250 ? 223.331 215.058 268.828 1.00 36.77  ? 250 VAL A C   1 
ATOM   1860  O  O   . VAL A 1 250 ? 223.325 215.843 267.869 1.00 36.77  ? 250 VAL A O   1 
ATOM   1861  C  CB  . VAL A 1 250 ? 222.265 216.136 270.840 1.00 36.77  ? 250 VAL A CB  1 
ATOM   1862  C  CG1 . VAL A 1 250 ? 222.423 216.284 272.318 1.00 36.77  ? 250 VAL A CG1 1 
ATOM   1863  C  CG2 . VAL A 1 250 ? 221.974 217.479 270.221 1.00 36.77  ? 250 VAL A CG2 1 
ATOM   1864  N  N   . MET A 1 251 ? 223.162 213.745 268.696 1.00 38.05  ? 251 MET A N   1 
ATOM   1865  C  CA  . MET A 1 251 ? 222.961 213.086 267.418 1.00 38.05  ? 251 MET A CA  1 
ATOM   1866  C  C   . MET A 1 251 ? 221.680 212.279 267.454 1.00 38.05  ? 251 MET A C   1 
ATOM   1867  O  O   . MET A 1 251 ? 221.455 211.495 268.377 1.00 38.05  ? 251 MET A O   1 
ATOM   1868  C  CB  . MET A 1 251 ? 224.123 212.156 267.079 1.00 38.05  ? 251 MET A CB  1 
ATOM   1869  C  CG  . MET A 1 251 ? 225.149 212.754 266.149 1.00 38.05  ? 251 MET A CG  1 
ATOM   1870  S  SD  . MET A 1 251 ? 226.648 211.768 266.081 1.00 38.05  ? 251 MET A SD  1 
ATOM   1871  C  CE  . MET A 1 251 ? 226.120 210.425 265.030 1.00 38.05  ? 251 MET A CE  1 
ATOM   1872  N  N   . THR A 1 252 ? 220.852 212.454 266.438 1.00 37.22  ? 252 THR A N   1 
ATOM   1873  C  CA  . THR A 1 252 ? 219.601 211.724 266.335 1.00 37.22  ? 252 THR A CA  1 
ATOM   1874  C  C   . THR A 1 252 ? 219.583 210.927 265.043 1.00 37.22  ? 252 THR A C   1 
ATOM   1875  O  O   . THR A 1 252 ? 219.864 211.464 263.969 1.00 37.22  ? 252 THR A O   1 
ATOM   1876  C  CB  . THR A 1 252 ? 218.392 212.659 266.375 1.00 37.22  ? 252 THR A CB  1 
ATOM   1877  O  OG1 . THR A 1 252 ? 218.251 213.311 265.107 1.00 37.22  ? 252 THR A OG1 1 
ATOM   1878  C  CG2 . THR A 1 252 ? 218.555 213.705 267.458 1.00 37.22  ? 252 THR A CG2 1 
ATOM   1879  N  N   . PHE A 1 253 ? 219.243 209.650 265.147 1.00 38.70  ? 253 PHE A N   1 
ATOM   1880  C  CA  . PHE A 1 253 ? 219.114 208.789 263.984 1.00 38.70  ? 253 PHE A CA  1 
ATOM   1881  C  C   . PHE A 1 253 ? 217.641 208.531 263.711 1.00 38.70  ? 253 PHE A C   1 
ATOM   1882  O  O   . PHE A 1 253 ? 216.772 208.833 264.531 1.00 38.70  ? 253 PHE A O   1 
ATOM   1883  C  CB  . PHE A 1 253 ? 219.847 207.461 264.185 1.00 38.70  ? 253 PHE A CB  1 
ATOM   1884  C  CG  . PHE A 1 253 ? 221.209 207.598 264.790 1.00 38.70  ? 253 PHE A CG  1 
ATOM   1885  C  CD1 . PHE A 1 253 ? 221.377 207.587 266.153 1.00 38.70  ? 253 PHE A CD1 1 
ATOM   1886  C  CD2 . PHE A 1 253 ? 222.325 207.706 263.991 1.00 38.70  ? 253 PHE A CD2 1 
ATOM   1887  C  CE1 . PHE A 1 253 ? 222.626 207.701 266.708 1.00 38.70  ? 253 PHE A CE1 1 
ATOM   1888  C  CE2 . PHE A 1 253 ? 223.575 207.813 264.542 1.00 38.70  ? 253 PHE A CE2 1 
ATOM   1889  C  CZ  . PHE A 1 253 ? 223.725 207.811 265.900 1.00 38.70  ? 253 PHE A CZ  1 
ATOM   1890  N  N   . SER A 1 254 ? 217.360 207.964 262.543 1.00 46.12  ? 254 SER A N   1 
ATOM   1891  C  CA  . SER A 1 254 ? 215.989 207.636 262.186 1.00 46.12  ? 254 SER A CA  1 
ATOM   1892  C  C   . SER A 1 254 ? 216.005 206.642 261.036 1.00 46.12  ? 254 SER A C   1 
ATOM   1893  O  O   . SER A 1 254 ? 216.828 206.757 260.124 1.00 46.12  ? 254 SER A O   1 
ATOM   1894  C  CB  . SER A 1 254 ? 215.201 208.889 261.795 1.00 46.12  ? 254 SER A CB  1 
ATOM   1895  O  OG  . SER A 1 254 ? 213.836 208.580 261.578 1.00 46.12  ? 254 SER A OG  1 
ATOM   1896  N  N   . ASP A 1 255 ? 215.091 205.678 261.084 1.00 49.98  ? 255 ASP A N   1 
ATOM   1897  C  CA  . ASP A 1 255 ? 215.009 204.635 260.070 1.00 49.98  ? 255 ASP A CA  1 
ATOM   1898  C  C   . ASP A 1 255 ? 214.270 205.171 258.853 1.00 49.98  ? 255 ASP A C   1 
ATOM   1899  O  O   . ASP A 1 255 ? 213.154 205.684 258.978 1.00 49.98  ? 255 ASP A O   1 
ATOM   1900  C  CB  . ASP A 1 255 ? 214.298 203.411 260.638 1.00 49.98  ? 255 ASP A CB  1 
ATOM   1901  C  CG  . ASP A 1 255 ? 214.634 202.142 259.890 1.00 49.98  ? 255 ASP A CG  1 
ATOM   1902  O  OD1 . ASP A 1 255 ? 214.989 202.228 258.698 1.00 49.98  ? 255 ASP A OD1 1 
ATOM   1903  O  OD2 . ASP A 1 255 ? 214.538 201.055 260.497 1.00 49.98  ? 255 ASP A OD2 1 
ATOM   1904  N  N   . ILE A 1 256 ? 214.883 205.059 257.678 1.00 50.44  ? 256 ILE A N   1 
ATOM   1905  C  CA  . ILE A 1 256 ? 214.303 205.633 256.471 1.00 50.44  ? 256 ILE A CA  1 
ATOM   1906  C  C   . ILE A 1 256 ? 214.186 204.598 255.361 1.00 50.44  ? 256 ILE A C   1 
ATOM   1907  O  O   . ILE A 1 256 ? 214.292 204.939 254.180 1.00 50.44  ? 256 ILE A O   1 
ATOM   1908  C  CB  . ILE A 1 256 ? 215.117 206.843 255.980 1.00 50.44  ? 256 ILE A CB  1 
ATOM   1909  C  CG1 . ILE A 1 256 ? 216.564 206.442 255.720 1.00 50.44  ? 256 ILE A CG1 1 
ATOM   1910  C  CG2 . ILE A 1 256 ? 215.046 207.979 256.984 1.00 50.44  ? 256 ILE A CG2 1 
ATOM   1911  C  CD1 . ILE A 1 256 ? 217.238 207.279 254.663 1.00 50.44  ? 256 ILE A CD1 1 
ATOM   1912  N  N   . THR A 1 257 ? 213.979 203.329 255.715 1.00 52.82  ? 257 THR A N   1 
ATOM   1913  C  CA  . THR A 1 257 ? 213.811 202.310 254.682 1.00 52.82  ? 257 THR A CA  1 
ATOM   1914  C  C   . THR A 1 257 ? 212.556 202.566 253.858 1.00 52.82  ? 257 THR A C   1 
ATOM   1915  O  O   . THR A 1 257 ? 212.603 202.610 252.620 1.00 52.82  ? 257 THR A O   1 
ATOM   1916  C  CB  . THR A 1 257 ? 213.757 200.924 255.318 1.00 52.82  ? 257 THR A CB  1 
ATOM   1917  O  OG1 . THR A 1 257 ? 212.721 200.895 256.307 1.00 52.82  ? 257 THR A OG1 1 
ATOM   1918  C  CG2 . THR A 1 257 ? 215.086 200.583 255.966 1.00 52.82  ? 257 THR A CG2 1 
ATOM   1919  N  N   . GLU A 1 258 ? 211.421 202.749 254.533 1.00 57.99  ? 258 GLU A N   1 
ATOM   1920  C  CA  . GLU A 1 258 ? 210.178 203.054 253.833 1.00 57.99  ? 258 GLU A CA  1 
ATOM   1921  C  C   . GLU A 1 258 ? 210.284 204.372 253.079 1.00 57.99  ? 258 GLU A C   1 
ATOM   1922  O  O   . GLU A 1 258 ? 209.808 204.492 251.943 1.00 57.99  ? 258 GLU A O   1 
ATOM   1923  C  CB  . GLU A 1 258 ? 209.026 203.106 254.831 1.00 57.99  ? 258 GLU A CB  1 
ATOM   1924  C  CG  . GLU A 1 258 ? 208.764 201.796 255.532 1.00 57.99  ? 258 GLU A CG  1 
ATOM   1925  C  CD  . GLU A 1 258 ? 207.666 201.906 256.568 1.00 57.99  ? 258 GLU A CD  1 
ATOM   1926  O  OE1 . GLU A 1 258 ? 207.211 203.037 256.833 1.00 57.99  ? 258 GLU A OE1 1 
ATOM   1927  O  OE2 . GLU A 1 258 ? 207.257 200.861 257.116 1.00 57.99  ? 258 GLU A OE2 1 
ATOM   1928  N  N   . GLU A 1 259 ? 210.904 205.372 253.700 1.00 56.10  ? 259 GLU A N   1 
ATOM   1929  C  CA  . GLU A 1 259 ? 211.066 206.665 253.056 1.00 56.10  ? 259 GLU A CA  1 
ATOM   1930  C  C   . GLU A 1 259 ? 211.871 206.534 251.775 1.00 56.10  ? 259 GLU A C   1 
ATOM   1931  O  O   . GLU A 1 259 ? 211.549 207.161 250.761 1.00 56.10  ? 259 GLU A O   1 
ATOM   1932  C  CB  . GLU A 1 259 ? 211.748 207.635 254.023 1.00 56.10  ? 259 GLU A CB  1 
ATOM   1933  C  CG  . GLU A 1 259 ? 211.890 209.052 253.510 1.00 56.10  ? 259 GLU A CG  1 
ATOM   1934  C  CD  . GLU A 1 259 ? 210.564 209.772 253.414 1.00 56.10  ? 259 GLU A CD  1 
ATOM   1935  O  OE1 . GLU A 1 259 ? 209.639 209.415 254.173 1.00 56.10  ? 259 GLU A OE1 1 
ATOM   1936  O  OE2 . GLU A 1 259 ? 210.446 210.696 252.582 1.00 56.10  ? 259 GLU A OE2 1 
ATOM   1937  N  N   . ARG A 1 260 ? 212.921 205.717 251.798 1.00 56.07  ? 260 ARG A N   1 
ATOM   1938  C  CA  . ARG A 1 260 ? 213.759 205.566 250.620 1.00 56.07  ? 260 ARG A CA  1 
ATOM   1939  C  C   . ARG A 1 260 ? 213.053 204.771 249.537 1.00 56.07  ? 260 ARG A C   1 
ATOM   1940  O  O   . ARG A 1 260 ? 213.246 205.046 248.347 1.00 56.07  ? 260 ARG A O   1 
ATOM   1941  C  CB  . ARG A 1 260 ? 215.083 204.913 250.999 1.00 56.07  ? 260 ARG A CB  1 
ATOM   1942  C  CG  . ARG A 1 260 ? 216.076 204.859 249.873 1.00 56.07  ? 260 ARG A CG  1 
ATOM   1943  C  CD  . ARG A 1 260 ? 217.481 204.686 250.392 1.00 56.07  ? 260 ARG A CD  1 
ATOM   1944  N  NE  . ARG A 1 260 ? 218.007 205.938 250.916 1.00 56.07  ? 260 ARG A NE  1 
ATOM   1945  C  CZ  . ARG A 1 260 ? 218.514 206.908 250.166 1.00 56.07  ? 260 ARG A CZ  1 
ATOM   1946  N  NH1 . ARG A 1 260 ? 218.582 206.801 248.849 1.00 56.07  ? 260 ARG A NH1 1 
ATOM   1947  N  NH2 . ARG A 1 260 ? 218.964 208.013 250.753 1.00 56.07  ? 260 ARG A NH2 1 
ATOM   1948  N  N   . GLN A 1 261 ? 212.220 203.804 249.923 1.00 58.91  ? 261 GLN A N   1 
ATOM   1949  C  CA  . GLN A 1 261 ? 211.378 203.142 248.932 1.00 58.91  ? 261 GLN A CA  1 
ATOM   1950  C  C   . GLN A 1 261 ? 210.439 204.139 248.264 1.00 58.91  ? 261 GLN A C   1 
ATOM   1951  O  O   . GLN A 1 261 ? 210.265 204.122 247.037 1.00 58.91  ? 261 GLN A O   1 
ATOM   1952  C  CB  . GLN A 1 261 ? 210.586 202.009 249.584 1.00 58.91  ? 261 GLN A CB  1 
ATOM   1953  C  CG  . GLN A 1 261 ? 211.447 200.886 250.137 1.00 58.91  ? 261 GLN A CG  1 
ATOM   1954  C  CD  . GLN A 1 261 ? 212.226 200.158 249.058 1.00 58.91  ? 261 GLN A CD  1 
ATOM   1955  O  OE1 . GLN A 1 261 ? 211.796 200.087 247.907 1.00 58.91  ? 261 GLN A OE1 1 
ATOM   1956  N  NE2 . GLN A 1 261 ? 213.379 199.614 249.427 1.00 58.91  ? 261 GLN A NE2 1 
ATOM   1957  N  N   . ILE A 1 262 ? 209.835 205.027 249.054 1.00 54.82  ? 262 ILE A N   1 
ATOM   1958  C  CA  . ILE A 1 262 ? 208.940 206.028 248.482 1.00 54.82  ? 262 ILE A CA  1 
ATOM   1959  C  C   . ILE A 1 262 ? 209.709 206.963 247.564 1.00 54.82  ? 262 ILE A C   1 
ATOM   1960  O  O   . ILE A 1 262 ? 209.205 207.386 246.516 1.00 54.82  ? 262 ILE A O   1 
ATOM   1961  C  CB  . ILE A 1 262 ? 208.212 206.803 249.593 1.00 54.82  ? 262 ILE A CB  1 
ATOM   1962  C  CG1 . ILE A 1 262 ? 207.440 205.843 250.492 1.00 54.82  ? 262 ILE A CG1 1 
ATOM   1963  C  CG2 . ILE A 1 262 ? 207.268 207.826 248.994 1.00 54.82  ? 262 ILE A CG2 1 
ATOM   1964  C  CD1 . ILE A 1 262 ? 206.713 204.769 249.738 1.00 54.82  ? 262 ILE A CD1 1 
ATOM   1965  N  N   . ARG A 1 263 ? 210.936 207.313 247.945 1.00 54.49  ? 263 ARG A N   1 
ATOM   1966  C  CA  . ARG A 1 263 ? 211.740 208.187 247.099 1.00 54.49  ? 263 ARG A CA  1 
ATOM   1967  C  C   . ARG A 1 263 ? 212.097 207.507 245.786 1.00 54.49  ? 263 ARG A C   1 
ATOM   1968  O  O   . ARG A 1 263 ? 212.123 208.155 244.736 1.00 54.49  ? 263 ARG A O   1 
ATOM   1969  C  CB  . ARG A 1 263 ? 213.003 208.629 247.830 1.00 54.49  ? 263 ARG A CB  1 
ATOM   1970  C  CG  . ARG A 1 263 ? 213.473 210.008 247.404 1.00 54.49  ? 263 ARG A CG  1 
ATOM   1971  C  CD  . ARG A 1 263 ? 214.775 210.432 248.076 1.00 54.49  ? 263 ARG A CD  1 
ATOM   1972  N  NE  . ARG A 1 263 ? 214.949 209.918 249.430 1.00 54.49  ? 263 ARG A NE  1 
ATOM   1973  C  CZ  . ARG A 1 263 ? 214.169 210.210 250.463 1.00 54.49  ? 263 ARG A CZ  1 
ATOM   1974  N  NH1 . ARG A 1 263 ? 213.095 210.970 250.328 1.00 54.49  ? 263 ARG A NH1 1 
ATOM   1975  N  NH2 . ARG A 1 263 ? 214.477 209.728 251.662 1.00 54.49  ? 263 ARG A NH2 1 
ATOM   1976  N  N   . GLN A 1 264 ? 212.392 206.207 245.827 1.00 54.14  ? 264 GLN A N   1 
ATOM   1977  C  CA  . GLN A 1 264 ? 212.646 205.477 244.589 1.00 54.14  ? 264 GLN A CA  1 
ATOM   1978  C  C   . GLN A 1 264 ? 211.411 205.469 243.701 1.00 54.14  ? 264 GLN A C   1 
ATOM   1979  O  O   . GLN A 1 264 ? 211.510 205.657 242.481 1.00 54.14  ? 264 GLN A O   1 
ATOM   1980  C  CB  . GLN A 1 264 ? 213.094 204.051 244.899 1.00 54.14  ? 264 GLN A CB  1 
ATOM   1981  C  CG  . GLN A 1 264 ? 214.492 203.955 245.490 1.00 54.14  ? 264 GLN A CG  1 
ATOM   1982  C  CD  . GLN A 1 264 ? 215.582 204.004 244.436 1.00 54.14  ? 264 GLN A CD  1 
ATOM   1983  O  OE1 . GLN A 1 264 ? 215.320 204.285 243.266 1.00 54.14  ? 264 GLN A OE1 1 
ATOM   1984  N  NE2 . GLN A 1 264 ? 216.814 203.730 244.847 1.00 54.14  ? 264 GLN A NE2 1 
ATOM   1985  N  N   . LEU A 1 265 ? 210.236 205.255 244.298 1.00 50.89  ? 265 LEU A N   1 
ATOM   1986  C  CA  . LEU A 1 265 ? 208.998 205.338 243.529 1.00 50.89  ? 265 LEU A CA  1 
ATOM   1987  C  C   . LEU A 1 265 ? 208.868 206.697 242.859 1.00 50.89  ? 265 LEU A C   1 
ATOM   1988  O  O   . LEU A 1 265 ? 208.568 206.789 241.662 1.00 50.89  ? 265 LEU A O   1 
ATOM   1989  C  CB  . LEU A 1 265 ? 207.792 205.079 244.430 1.00 50.89  ? 265 LEU A CB  1 
ATOM   1990  C  CG  . LEU A 1 265 ? 206.418 205.110 243.757 1.00 50.89  ? 265 LEU A CG  1 
ATOM   1991  C  CD1 . LEU A 1 265 ? 205.507 204.094 244.395 1.00 50.89  ? 265 LEU A CD1 1 
ATOM   1992  C  CD2 . LEU A 1 265 ? 205.785 206.481 243.843 1.00 50.89  ? 265 LEU A CD2 1 
ATOM   1993  N  N   . GLU A 1 266 ? 209.074 207.765 243.628 1.00 50.99  ? 266 GLU A N   1 
ATOM   1994  C  CA  . GLU A 1 266 ? 208.918 209.109 243.087 1.00 50.99  ? 266 GLU A CA  1 
ATOM   1995  C  C   . GLU A 1 266 ? 209.903 209.358 241.958 1.00 50.99  ? 266 GLU A C   1 
ATOM   1996  O  O   . GLU A 1 266 ? 209.549 209.934 240.923 1.00 50.99  ? 266 GLU A O   1 
ATOM   1997  C  CB  . GLU A 1 266 ? 209.104 210.142 244.195 1.00 50.99  ? 266 GLU A CB  1 
ATOM   1998  C  CG  . GLU A 1 266 ? 207.859 210.402 245.019 1.00 50.99  ? 266 GLU A CG  1 
ATOM   1999  C  CD  . GLU A 1 266 ? 207.881 211.764 245.678 1.00 50.99  ? 266 GLU A CD  1 
ATOM   2000  O  OE1 . GLU A 1 266 ? 208.767 212.574 245.337 1.00 50.99  ? 266 GLU A OE1 1 
ATOM   2001  O  OE2 . GLU A 1 266 ? 207.018 212.023 246.541 1.00 50.99  ? 266 GLU A OE2 1 
ATOM   2002  N  N   . GLY A 1 267 ? 211.149 208.928 242.143 1.00 52.75  ? 267 GLY A N   1 
ATOM   2003  C  CA  . GLY A 1 267 ? 212.151 209.133 241.113 1.00 52.75  ? 267 GLY A CA  1 
ATOM   2004  C  C   . GLY A 1 267 ? 211.805 208.420 239.823 1.00 52.75  ? 267 GLY A C   1 
ATOM   2005  O  O   . GLY A 1 267 ? 211.900 208.995 238.737 1.00 52.75  ? 267 GLY A O   1 
ATOM   2006  N  N   . ASN A 1 268 ? 211.383 207.159 239.925 1.00 51.01  ? 268 ASN A N   1 
ATOM   2007  C  CA  . ASN A 1 268 ? 211.025 206.414 238.723 1.00 51.01  ? 268 ASN A CA  1 
ATOM   2008  C  C   . ASN A 1 268 ? 209.825 207.036 238.024 1.00 51.01  ? 268 ASN A C   1 
ATOM   2009  O  O   . ASN A 1 268 ? 209.803 207.158 236.792 1.00 51.01  ? 268 ASN A O   1 
ATOM   2010  C  CB  . ASN A 1 268 ? 210.744 204.959 239.078 1.00 51.01  ? 268 ASN A CB  1 
ATOM   2011  C  CG  . ASN A 1 268 ? 211.902 204.309 239.783 1.00 51.01  ? 268 ASN A CG  1 
ATOM   2012  O  OD1 . ASN A 1 268 ? 212.943 204.929 239.981 1.00 51.01  ? 268 ASN A OD1 1 
ATOM   2013  N  ND2 . ASN A 1 268 ? 211.732 203.051 240.170 1.00 51.01  ? 268 ASN A ND2 1 
ATOM   2014  N  N   . ILE A 1 269 ? 208.804 207.422 238.789 1.00 49.13  ? 269 ILE A N   1 
ATOM   2015  C  CA  . ILE A 1 269 ? 207.592 207.931 238.160 1.00 49.13  ? 269 ILE A CA  1 
ATOM   2016  C  C   . ILE A 1 269 ? 207.853 209.282 237.510 1.00 49.13  ? 269 ILE A C   1 
ATOM   2017  O  O   . ILE A 1 269 ? 207.309 209.581 236.445 1.00 49.13  ? 269 ILE A O   1 
ATOM   2018  C  CB  . ILE A 1 269 ? 206.435 207.988 239.166 1.00 49.13  ? 269 ILE A CB  1 
ATOM   2019  C  CG1 . ILE A 1 269 ? 206.095 206.581 239.641 1.00 49.13  ? 269 ILE A CG1 1 
ATOM   2020  C  CG2 . ILE A 1 269 ? 205.214 208.589 238.523 1.00 49.13  ? 269 ILE A CG2 1 
ATOM   2021  C  CD1 . ILE A 1 269 ? 205.623 205.684 238.537 1.00 49.13  ? 269 ILE A CD1 1 
ATOM   2022  N  N   . LEU A 1 270 ? 208.690 210.119 238.127 1.00 51.41  ? 270 LEU A N   1 
ATOM   2023  C  CA  . LEU A 1 270 ? 209.135 211.327 237.439 1.00 51.41  ? 270 LEU A CA  1 
ATOM   2024  C  C   . LEU A 1 270 ? 209.910 210.994 236.175 1.00 51.41  ? 270 LEU A C   1 
ATOM   2025  O  O   . LEU A 1 270 ? 209.700 211.620 235.131 1.00 51.41  ? 270 LEU A O   1 
ATOM   2026  C  CB  . LEU A 1 270 ? 209.997 212.189 238.356 1.00 51.41  ? 270 LEU A CB  1 
ATOM   2027  C  CG  . LEU A 1 270 ? 209.351 212.939 239.501 1.00 51.41  ? 270 LEU A CG  1 
ATOM   2028  C  CD1 . LEU A 1 270 ? 210.418 213.554 240.367 1.00 51.41  ? 270 LEU A CD1 1 
ATOM   2029  C  CD2 . LEU A 1 270 ? 208.538 214.028 238.884 1.00 51.41  ? 270 LEU A CD2 1 
ATOM   2030  N  N   . ALA A 1 271 ? 210.823 210.024 236.249 1.00 53.72  ? 271 ALA A N   1 
ATOM   2031  C  CA  . ALA A 1 271 ? 211.623 209.683 235.080 1.00 53.72  ? 271 ALA A CA  1 
ATOM   2032  C  C   . ALA A 1 271 ? 210.747 209.224 233.928 1.00 53.72  ? 271 ALA A C   1 
ATOM   2033  O  O   . ALA A 1 271 ? 211.091 209.433 232.760 1.00 53.72  ? 271 ALA A O   1 
ATOM   2034  C  CB  . ALA A 1 271 ? 212.643 208.604 235.436 1.00 53.72  ? 271 ALA A CB  1 
ATOM   2035  N  N   . ALA A 1 272 ? 209.615 208.599 234.238 1.00 51.00  ? 272 ALA A N   1 
ATOM   2036  C  CA  . ALA A 1 272 ? 208.689 208.207 233.184 1.00 51.00  ? 272 ALA A CA  1 
ATOM   2037  C  C   . ALA A 1 272 ? 207.841 209.381 232.711 1.00 51.00  ? 272 ALA A C   1 
ATOM   2038  O  O   . ALA A 1 272 ? 207.742 209.632 231.505 1.00 51.00  ? 272 ALA A O   1 
ATOM   2039  C  CB  . ALA A 1 272 ? 207.794 207.068 233.668 1.00 51.00  ? 272 ALA A CB  1 
ATOM   2040  N  N   . MET A 1 273 ? 207.236 210.119 233.631 1.00 51.08  ? 273 MET A N   1 
ATOM   2041  C  CA  . MET A 1 273 ? 206.241 211.118 233.277 1.00 51.08  ? 273 MET A CA  1 
ATOM   2042  C  C   . MET A 1 273 ? 206.850 212.406 232.757 1.00 51.08  ? 273 MET A C   1 
ATOM   2043  O  O   . MET A 1 273 ? 206.120 213.248 232.229 1.00 51.08  ? 273 MET A O   1 
ATOM   2044  C  CB  . MET A 1 273 ? 205.345 211.414 234.481 1.00 51.08  ? 273 MET A CB  1 
ATOM   2045  C  CG  . MET A 1 273 ? 203.928 211.768 234.107 1.00 51.08  ? 273 MET A CG  1 
ATOM   2046  S  SD  . MET A 1 273 ? 202.775 211.342 235.413 1.00 51.08  ? 273 MET A SD  1 
ATOM   2047  C  CE  . MET A 1 273 ? 203.414 212.343 236.742 1.00 51.08  ? 273 MET A CE  1 
ATOM   2048  N  N   . CYS A 1 274 ? 208.161 212.587 232.893 1.00 57.56  ? 274 CYS A N   1 
ATOM   2049  C  CA  . CYS A 1 274 ? 208.824 213.660 232.172 1.00 57.56  ? 274 CYS A CA  1 
ATOM   2050  C  C   . CYS A 1 274 ? 208.884 213.381 230.679 1.00 57.56  ? 274 CYS A C   1 
ATOM   2051  O  O   . CYS A 1 274 ? 208.839 214.323 229.881 1.00 57.56  ? 274 CYS A O   1 
ATOM   2052  C  CB  . CYS A 1 274 ? 210.234 213.875 232.721 1.00 57.56  ? 274 CYS A CB  1 
ATOM   2053  S  SG  . CYS A 1 274 ? 210.286 214.732 234.312 1.00 57.56  ? 274 CYS A SG  1 
ATOM   2054  N  N   . SER A 1 275 ? 208.981 212.111 230.290 1.00 54.48  ? 275 SER A N   1 
ATOM   2055  C  CA  . SER A 1 275 ? 208.889 211.708 228.895 1.00 54.48  ? 275 SER A CA  1 
ATOM   2056  C  C   . SER A 1 275 ? 207.458 211.488 228.434 1.00 54.48  ? 275 SER A C   1 
ATOM   2057  O  O   . SER A 1 275 ? 207.191 211.562 227.232 1.00 54.48  ? 275 SER A O   1 
ATOM   2058  C  CB  . SER A 1 275 ? 209.690 210.425 228.663 1.00 54.48  ? 275 SER A CB  1 
ATOM   2059  O  OG  . SER A 1 275 ? 208.955 209.292 229.083 1.00 54.48  ? 275 SER A OG  1 
ATOM   2060  N  N   . SER A 1 276 ? 206.540 211.222 229.363 1.00 58.38  ? 276 SER A N   1 
ATOM   2061  C  CA  . SER A 1 276 ? 205.119 211.035 229.083 1.00 58.38  ? 276 SER A CA  1 
ATOM   2062  C  C   . SER A 1 276 ? 204.857 209.875 228.130 1.00 58.38  ? 276 SER A C   1 
ATOM   2063  O  O   . SER A 1 276 ? 204.479 210.099 226.974 1.00 58.38  ? 276 SER A O   1 
ATOM   2064  C  CB  . SER A 1 276 ? 204.511 212.314 228.506 1.00 58.38  ? 276 SER A CB  1 
ATOM   2065  O  OG  . SER A 1 276 ? 203.225 212.061 227.966 1.00 58.38  ? 276 SER A OG  1 
ATOM   2066  N  N   . PRO A 1 277 ? 205.035 208.633 228.569 1.00 59.56  ? 277 PRO A N   1 
ATOM   2067  C  CA  . PRO A 1 277 ? 204.682 207.491 227.729 1.00 59.56  ? 277 PRO A CA  1 
ATOM   2068  C  C   . PRO A 1 277 ? 203.180 207.428 227.530 1.00 59.56  ? 277 PRO A C   1 
ATOM   2069  O  O   . PRO A 1 277 ? 202.441 208.228 228.123 1.00 59.56  ? 277 PRO A O   1 
ATOM   2070  C  CB  . PRO A 1 277 ? 205.192 206.293 228.540 1.00 59.56  ? 277 PRO A CB  1 
ATOM   2071  C  CG  . PRO A 1 277 ? 205.121 206.745 229.932 1.00 59.56  ? 277 PRO A CG  1 
ATOM   2072  C  CD  . PRO A 1 277 ? 205.458 208.210 229.912 1.00 59.56  ? 277 PRO A CD  1 
ATOM   2073  N  N   . PRO A 1 278 ? 202.685 206.513 226.698 1.00 62.43  ? 278 PRO A N   1 
ATOM   2074  C  CA  . PRO A 1 278 ? 201.234 206.414 226.508 1.00 62.43  ? 278 PRO A CA  1 
ATOM   2075  C  C   . PRO A 1 278 ? 200.518 206.137 227.821 1.00 62.43  ? 278 PRO A C   1 
ATOM   2076  O  O   . PRO A 1 278 ? 201.110 205.660 228.791 1.00 62.43  ? 278 PRO A O   1 
ATOM   2077  C  CB  . PRO A 1 278 ? 201.078 205.248 225.524 1.00 62.43  ? 278 PRO A CB  1 
ATOM   2078  C  CG  . PRO A 1 278 ? 202.414 204.566 225.497 1.00 62.43  ? 278 PRO A CG  1 
ATOM   2079  C  CD  . PRO A 1 278 ? 203.409 205.636 225.766 1.00 62.43  ? 278 PRO A CD  1 
ATOM   2080  N  N   . PHE A 1 279 ? 199.223 206.456 227.838 1.00 66.02  ? 279 PHE A N   1 
ATOM   2081  C  CA  . PHE A 1 279 ? 198.449 206.438 229.075 1.00 66.02  ? 279 PHE A CA  1 
ATOM   2082  C  C   . PHE A 1 279 ? 198.439 205.054 229.706 1.00 66.02  ? 279 PHE A C   1 
ATOM   2083  O  O   . PHE A 1 279 ? 198.677 204.897 230.913 1.00 66.02  ? 279 PHE A O   1 
ATOM   2084  C  CB  . PHE A 1 279 ? 197.025 206.907 228.777 1.00 66.02  ? 279 PHE A CB  1 
ATOM   2085  C  CG  . PHE A 1 279 ? 196.180 207.118 229.994 1.00 66.02  ? 279 PHE A CG  1 
ATOM   2086  C  CD1 . PHE A 1 279 ? 196.502 208.098 230.916 1.00 66.02  ? 279 PHE A CD1 1 
ATOM   2087  C  CD2 . PHE A 1 279 ? 195.042 206.360 230.200 1.00 66.02  ? 279 PHE A CD2 1 
ATOM   2088  C  CE1 . PHE A 1 279 ? 195.716 208.301 232.034 1.00 66.02  ? 279 PHE A CE1 1 
ATOM   2089  C  CE2 . PHE A 1 279 ? 194.252 206.559 231.310 1.00 66.02  ? 279 PHE A CE2 1 
ATOM   2090  C  CZ  . PHE A 1 279 ? 194.588 207.530 232.230 1.00 66.02  ? 279 PHE A CZ  1 
ATOM   2091  N  N   . HIS A 1 280 ? 198.163 204.033 228.897 1.00 67.44  ? 280 HIS A N   1 
ATOM   2092  C  CA  . HIS A 1 280 ? 198.032 202.682 229.416 1.00 67.44  ? 280 HIS A CA  1 
ATOM   2093  C  C   . HIS A 1 280 ? 199.362 202.094 229.847 1.00 67.44  ? 280 HIS A C   1 
ATOM   2094  O  O   . HIS A 1 280 ? 199.370 201.082 230.555 1.00 67.44  ? 280 HIS A O   1 
ATOM   2095  C  CB  . HIS A 1 280 ? 197.369 201.793 228.371 1.00 67.44  ? 280 HIS A CB  1 
ATOM   2096  C  CG  . HIS A 1 280 ? 195.920 202.099 228.163 1.00 67.44  ? 280 HIS A CG  1 
ATOM   2097  N  ND1 . HIS A 1 280 ? 195.036 202.255 229.208 1.00 67.44  ? 280 HIS A ND1 1 
ATOM   2098  C  CD2 . HIS A 1 280 ? 195.201 202.290 227.032 1.00 67.44  ? 280 HIS A CD2 1 
ATOM   2099  C  CE1 . HIS A 1 280 ? 193.834 202.522 228.730 1.00 67.44  ? 280 HIS A CE1 1 
ATOM   2100  N  NE2 . HIS A 1 280 ? 193.907 202.548 227.412 1.00 67.44  ? 280 HIS A NE2 1 
ATOM   2101  N  N   . GLU A 1 281 ? 200.477 202.693 229.443 1.00 67.99  ? 281 GLU A N   1 
ATOM   2102  C  CA  . GLU A 1 281 ? 201.777 202.287 229.949 1.00 67.99  ? 281 GLU A CA  1 
ATOM   2103  C  C   . GLU A 1 281 ? 202.194 203.063 231.186 1.00 67.99  ? 281 GLU A C   1 
ATOM   2104  O  O   . GLU A 1 281 ? 202.862 202.500 232.059 1.00 67.99  ? 281 GLU A O   1 
ATOM   2105  C  CB  . GLU A 1 281 ? 202.846 202.446 228.866 1.00 67.99  ? 281 GLU A CB  1 
ATOM   2106  C  CG  . GLU A 1 281 ? 204.044 201.542 229.061 1.00 67.99  ? 281 GLU A CG  1 
ATOM   2107  C  CD  . GLU A 1 281 ? 204.702 201.162 227.753 1.00 67.99  ? 281 GLU A CD  1 
ATOM   2108  O  OE1 . GLU A 1 281 ? 204.308 201.717 226.707 1.00 67.99  ? 281 GLU A OE1 1 
ATOM   2109  O  OE2 . GLU A 1 281 ? 205.617 200.314 227.770 1.00 67.99  ? 281 GLU A OE2 1 
ATOM   2110  N  N   . MET A 1 282 ? 201.812 204.337 231.290 1.00 64.84  ? 282 MET A N   1 
ATOM   2111  C  CA  . MET A 1 282 ? 202.037 205.060 232.536 1.00 64.84  ? 282 MET A CA  1 
ATOM   2112  C  C   . MET A 1 282 ? 201.270 204.406 233.673 1.00 64.84  ? 282 MET A C   1 
ATOM   2113  O  O   . MET A 1 282 ? 201.778 204.293 234.798 1.00 64.84  ? 282 MET A O   1 
ATOM   2114  C  CB  . MET A 1 282 ? 201.633 206.524 232.381 1.00 64.84  ? 282 MET A CB  1 
ATOM   2115  C  CG  . MET A 1 282 ? 201.520 207.280 233.690 1.00 64.84  ? 282 MET A CG  1 
ATOM   2116  S  SD  . MET A 1 282 ? 203.078 207.386 234.583 1.00 64.84  ? 282 MET A SD  1 
ATOM   2117  C  CE  . MET A 1 282 ? 204.167 207.951 233.286 1.00 64.84  ? 282 MET A CE  1 
ATOM   2118  N  N   . GLY A 1 283 ? 200.048 203.955 233.395 1.00 66.80  ? 283 GLY A N   1 
ATOM   2119  C  CA  . GLY A 1 283 ? 199.308 203.227 234.410 1.00 66.80  ? 283 GLY A CA  1 
ATOM   2120  C  C   . GLY A 1 283 ? 200.034 201.974 234.856 1.00 66.80  ? 283 GLY A C   1 
ATOM   2121  O  O   . GLY A 1 283 ? 200.117 201.674 236.053 1.00 66.80  ? 283 GLY A O   1 
ATOM   2122  N  N   . GLU A 1 284 ? 200.578 201.229 233.896 1.00 73.45  ? 284 GLU A N   1 
ATOM   2123  C  CA  . GLU A 1 284 ? 201.290 200.005 234.233 1.00 73.45  ? 284 GLU A CA  1 
ATOM   2124  C  C   . GLU A 1 284 ? 202.540 200.307 235.040 1.00 73.45  ? 284 GLU A C   1 
ATOM   2125  O  O   . GLU A 1 284 ? 202.891 199.556 235.954 1.00 73.45  ? 284 GLU A O   1 
ATOM   2126  C  CB  . GLU A 1 284 ? 201.640 199.233 232.961 1.00 73.45  ? 284 GLU A CB  1 
ATOM   2127  C  CG  . GLU A 1 284 ? 200.449 198.553 232.303 1.00 73.45  ? 284 GLU A CG  1 
ATOM   2128  C  CD  . GLU A 1 284 ? 199.953 197.353 233.088 1.00 73.45  ? 284 GLU A CD  1 
ATOM   2129  O  OE1 . GLU A 1 284 ? 200.728 196.807 233.900 1.00 73.45  ? 284 GLU A OE1 1 
ATOM   2130  O  OE2 . GLU A 1 284 ? 198.784 196.956 232.893 1.00 73.45  ? 284 GLU A OE2 1 
ATOM   2131  N  N   . ILE A 1 285 ? 203.229 201.400 234.714 1.00 66.92  ? 285 ILE A N   1 
ATOM   2132  C  CA  . ILE A 1 285 ? 204.416 201.784 235.472 1.00 66.92  ? 285 ILE A CA  1 
ATOM   2133  C  C   . ILE A 1 285 ? 204.042 202.088 236.916 1.00 66.92  ? 285 ILE A C   1 
ATOM   2134  O  O   . ILE A 1 285 ? 204.709 201.641 237.861 1.00 66.92  ? 285 ILE A O   1 
ATOM   2135  C  CB  . ILE A 1 285 ? 205.109 202.985 234.810 1.00 66.92  ? 285 ILE A CB  1 
ATOM   2136  C  CG1 . ILE A 1 285 ? 205.658 202.603 233.440 1.00 66.92  ? 285 ILE A CG1 1 
ATOM   2137  C  CG2 . ILE A 1 285 ? 206.234 203.499 235.688 1.00 66.92  ? 285 ILE A CG2 1 
ATOM   2138  C  CD1 . ILE A 1 285 ? 206.441 203.713 232.787 1.00 66.92  ? 285 ILE A CD1 1 
ATOM   2139  N  N   . ILE A 1 286 ? 202.965 202.851 237.106 1.00 65.94  ? 286 ILE A N   1 
ATOM   2140  C  CA  . ILE A 1 286 ? 202.535 203.187 238.460 1.00 65.94  ? 286 ILE A CA  1 
ATOM   2141  C  C   . ILE A 1 286 ? 202.197 201.920 239.233 1.00 65.94  ? 286 ILE A C   1 
ATOM   2142  O  O   . ILE A 1 286 ? 202.626 201.737 240.380 1.00 65.94  ? 286 ILE A O   1 
ATOM   2143  C  CB  . ILE A 1 286 ? 201.346 204.160 238.429 1.00 65.94  ? 286 ILE A CB  1 
ATOM   2144  C  CG1 . ILE A 1 286 ? 201.835 205.587 238.217 1.00 65.94  ? 286 ILE A CG1 1 
ATOM   2145  C  CG2 . ILE A 1 286 ? 200.576 204.090 239.725 1.00 65.94  ? 286 ILE A CG2 1 
ATOM   2146  C  CD1 . ILE A 1 286 ? 200.724 206.597 238.125 1.00 65.94  ? 286 ILE A CD1 1 
ATOM   2147  N  N   . CYS A 1 287 ? 201.444 201.012 238.606 1.00 79.24  ? 287 CYS A N   1 
ATOM   2148  C  CA  . CYS A 1 287 ? 201.051 199.782 239.289 1.00 79.24  ? 287 CYS A CA  1 
ATOM   2149  C  C   . CYS A 1 287 ? 202.259 198.911 239.616 1.00 79.24  ? 287 CYS A C   1 
ATOM   2150  O  O   . CYS A 1 287 ? 202.328 198.307 240.695 1.00 79.24  ? 287 CYS A O   1 
ATOM   2151  C  CB  . CYS A 1 287 ? 200.046 199.009 238.438 1.00 79.24  ? 287 CYS A CB  1 
ATOM   2152  S  SG  . CYS A 1 287 ? 198.429 199.796 238.305 1.00 79.24  ? 287 CYS A SG  1 
ATOM   2153  N  N   . ARG A 1 288 ? 203.214 198.818 238.689 1.00 75.61  ? 288 ARG A N   1 
ATOM   2154  C  CA  . ARG A 1 288 ? 204.394 197.996 238.917 1.00 75.61  ? 288 ARG A CA  1 
ATOM   2155  C  C   . ARG A 1 288 ? 205.202 198.523 240.093 1.00 75.61  ? 288 ARG A C   1 
ATOM   2156  O  O   . ARG A 1 288 ? 205.623 197.758 240.968 1.00 75.61  ? 288 ARG A O   1 
ATOM   2157  C  CB  . ARG A 1 288 ? 205.244 197.949 237.648 1.00 75.61  ? 288 ARG A CB  1 
ATOM   2158  C  CG  . ARG A 1 288 ? 206.303 196.857 237.635 1.00 75.61  ? 288 ARG A CG  1 
ATOM   2159  C  CD  . ARG A 1 288 ? 207.661 197.391 238.068 1.00 75.61  ? 288 ARG A CD  1 
ATOM   2160  N  NE  . ARG A 1 288 ? 208.122 198.474 237.208 1.00 75.61  ? 288 ARG A NE  1 
ATOM   2161  C  CZ  . ARG A 1 288 ? 209.102 199.312 237.518 1.00 75.61  ? 288 ARG A CZ  1 
ATOM   2162  N  NH1 . ARG A 1 288 ? 209.751 199.221 238.668 1.00 75.61  ? 288 ARG A NH1 1 
ATOM   2163  N  NH2 . ARG A 1 288 ? 209.439 200.265 236.655 1.00 75.61  ? 288 ARG A NH2 1 
ATOM   2164  N  N   . ASN A 1 289 ? 205.422 199.836 240.138 1.00 69.73  ? 289 ASN A N   1 
ATOM   2165  C  CA  . ASN A 1 289 ? 206.144 200.382 241.276 1.00 69.73  ? 289 ASN A CA  1 
ATOM   2166  C  C   . ASN A 1 289 ? 205.354 200.237 242.566 1.00 69.73  ? 289 ASN A C   1 
ATOM   2167  O  O   . ASN A 1 289 ? 205.957 200.049 243.627 1.00 69.73  ? 289 ASN A O   1 
ATOM   2168  C  CB  . ASN A 1 289 ? 206.497 201.842 241.029 1.00 69.73  ? 289 ASN A CB  1 
ATOM   2169  C  CG  . ASN A 1 289 ? 207.516 202.007 239.927 1.00 69.73  ? 289 ASN A CG  1 
ATOM   2170  O  OD1 . ASN A 1 289 ? 208.694 201.716 240.111 1.00 69.73  ? 289 ASN A OD1 1 
ATOM   2171  N  ND2 . ASN A 1 289 ? 207.066 202.476 238.773 1.00 69.73  ? 289 ASN A ND2 1 
ATOM   2172  N  N   . ILE A 1 290 ? 204.021 200.305 242.498 1.00 74.92  ? 290 ILE A N   1 
ATOM   2173  C  CA  . ILE A 1 290 ? 203.201 200.071 243.685 1.00 74.92  ? 290 ILE A CA  1 
ATOM   2174  C  C   . ILE A 1 290 ? 203.448 198.671 244.226 1.00 74.92  ? 290 ILE A C   1 
ATOM   2175  O  O   . ILE A 1 290 ? 203.635 198.469 245.432 1.00 74.92  ? 290 ILE A O   1 
ATOM   2176  C  CB  . ILE A 1 290 ? 201.713 200.286 243.360 1.00 74.92  ? 290 ILE A CB  1 
ATOM   2177  C  CG1 . ILE A 1 290 ? 201.391 201.770 243.289 1.00 74.92  ? 290 ILE A CG1 1 
ATOM   2178  C  CG2 . ILE A 1 290 ? 200.842 199.623 244.407 1.00 74.92  ? 290 ILE A CG2 1 
ATOM   2179  C  CD1 . ILE A 1 290 ? 201.573 202.460 244.590 1.00 74.92  ? 290 ILE A CD1 1 
ATOM   2180  N  N   . GLU A 1 291 ? 203.443 197.680 243.335 1.00 83.73  ? 291 GLU A N   1 
ATOM   2181  C  CA  . GLU A 1 291 ? 203.684 196.310 243.769 1.00 83.73  ? 291 GLU A CA  1 
ATOM   2182  C  C   . GLU A 1 291 ? 205.107 196.139 244.281 1.00 83.73  ? 291 GLU A C   1 
ATOM   2183  O  O   . GLU A 1 291 ? 205.357 195.327 245.179 1.00 83.73  ? 291 GLU A O   1 
ATOM   2184  C  CB  . GLU A 1 291 ? 203.399 195.334 242.628 1.00 83.73  ? 291 GLU A CB  1 
ATOM   2185  C  CG  . GLU A 1 291 ? 201.920 195.082 242.391 1.00 83.73  ? 291 GLU A CG  1 
ATOM   2186  C  CD  . GLU A 1 291 ? 201.366 193.978 243.273 1.00 83.73  ? 291 GLU A CD  1 
ATOM   2187  O  OE1 . GLU A 1 291 ? 202.125 193.439 244.106 1.00 83.73  ? 291 GLU A OE1 1 
ATOM   2188  O  OE2 . GLU A 1 291 ? 200.168 193.654 243.138 1.00 83.73  ? 291 GLU A OE2 1 
ATOM   2189  N  N   . SER A 1 292 ? 206.055 196.887 243.720 1.00 78.44  ? 292 SER A N   1 
ATOM   2190  C  CA  . SER A 1 292 ? 207.431 196.786 244.188 1.00 78.44  ? 292 SER A CA  1 
ATOM   2191  C  C   . SER A 1 292 ? 207.648 197.463 245.533 1.00 78.44  ? 292 SER A C   1 
ATOM   2192  O  O   . SER A 1 292 ? 208.601 197.111 246.234 1.00 78.44  ? 292 SER A O   1 
ATOM   2193  C  CB  . SER A 1 292 ? 208.388 197.381 243.156 1.00 78.44  ? 292 SER A CB  1 
ATOM   2194  O  OG  . SER A 1 292 ? 209.731 197.269 243.591 1.00 78.44  ? 292 SER A OG  1 
ATOM   2195  N  N   . VAL A 1 293 ? 206.806 198.427 245.901 1.00 78.18  ? 293 VAL A N   1 
ATOM   2196  C  CA  . VAL A 1 293 ? 206.987 199.146 247.157 1.00 78.18  ? 293 VAL A CA  1 
ATOM   2197  C  C   . VAL A 1 293 ? 206.124 198.538 248.260 1.00 78.18  ? 293 VAL A C   1 
ATOM   2198  O  O   . VAL A 1 293 ? 206.425 198.691 249.449 1.00 78.18  ? 293 VAL A O   1 
ATOM   2199  C  CB  . VAL A 1 293 ? 206.686 200.648 246.981 1.00 78.18  ? 293 VAL A CB  1 
ATOM   2200  C  CG1 . VAL A 1 293 ? 205.196 200.888 246.788 1.00 78.18  ? 293 VAL A CG1 1 
ATOM   2201  C  CG2 . VAL A 1 293 ? 207.219 201.448 248.163 1.00 78.18  ? 293 VAL A CG2 1 
ATOM   2202  N  N   . LEU A 1 294 ? 205.056 197.836 247.885 1.00 84.20  ? 294 LEU A N   1 
ATOM   2203  C  CA  . LEU A 1 294 ? 204.131 197.243 248.844 1.00 84.20  ? 294 LEU A CA  1 
ATOM   2204  C  C   . LEU A 1 294 ? 204.227 195.725 248.781 1.00 84.20  ? 294 LEU A C   1 
ATOM   2205  O  O   . LEU A 1 294 ? 204.528 195.162 247.724 1.00 84.20  ? 294 LEU A O   1 
ATOM   2206  C  CB  . LEU A 1 294 ? 202.694 197.692 248.569 1.00 84.20  ? 294 LEU A CB  1 
ATOM   2207  C  CG  . LEU A 1 294 ? 202.297 199.092 249.044 1.00 84.20  ? 294 LEU A CG  1 
ATOM   2208  C  CD1 . LEU A 1 294 ? 201.190 199.657 248.168 1.00 84.20  ? 294 LEU A CD1 1 
ATOM   2209  C  CD2 . LEU A 1 294 ? 201.863 199.065 250.502 1.00 84.20  ? 294 LEU A CD2 1 
ATOM   2210  N  N   . ASN A 1 295 ? 203.969 195.067 249.908 1.00 94.32  ? 295 ASN A N   1 
ATOM   2211  C  CA  . ASN A 1 295 ? 204.096 193.619 249.999 1.00 94.32  ? 295 ASN A CA  1 
ATOM   2212  C  C   . ASN A 1 295 ? 202.741 192.937 249.854 1.00 94.32  ? 295 ASN A C   1 
ATOM   2213  O  O   . ASN A 1 295 ? 201.785 193.277 250.557 1.00 94.32  ? 295 ASN A O   1 
ATOM   2214  C  CB  . ASN A 1 295 ? 204.739 193.222 251.329 1.00 94.32  ? 295 ASN A CB  1 
ATOM   2215  C  CG  . ASN A 1 295 ? 206.193 193.642 251.420 1.00 94.32  ? 295 ASN A CG  1 
ATOM   2216  O  OD1 . ASN A 1 295 ? 207.090 192.913 250.997 1.00 94.32  ? 295 ASN A OD1 1 
ATOM   2217  N  ND2 . ASN A 1 295 ? 206.434 194.825 251.973 1.00 94.32  ? 295 ASN A ND2 1 
ATOM   2218  N  N   . GLU A 1 296 ? 202.683 191.965 248.943 1.00 92.53  ? 296 GLU A N   1 
ATOM   2219  C  CA  . GLU A 1 296 ? 201.519 191.107 248.689 1.00 92.53  ? 296 GLU A CA  1 
ATOM   2220  C  C   . GLU A 1 296 ? 200.203 191.885 248.754 1.00 92.53  ? 296 GLU A C   1 
ATOM   2221  O  O   . GLU A 1 296 ? 199.305 191.594 249.543 1.00 92.53  ? 296 GLU A O   1 
ATOM   2222  C  CB  . GLU A 1 296 ? 201.504 189.901 249.635 1.00 92.53  ? 296 GLU A CB  1 
ATOM   2223  C  CG  . GLU A 1 296 ? 201.492 190.206 251.130 1.00 92.53  ? 296 GLU A CG  1 
ATOM   2224  C  CD  . GLU A 1 296 ? 202.847 190.001 251.779 1.00 92.53  ? 296 GLU A CD  1 
ATOM   2225  O  OE1 . GLU A 1 296 ? 203.851 189.895 251.044 1.00 92.53  ? 296 GLU A OE1 1 
ATOM   2226  O  OE2 . GLU A 1 296 ? 202.907 189.946 253.025 1.00 92.53  ? 296 GLU A OE2 1 
ATOM   2227  N  N   . SER A 1 297 ? 200.094 192.883 247.883 1.00 87.72  ? 297 SER A N   1 
ATOM   2228  C  CA  . SER A 1 297 ? 198.933 193.757 247.858 1.00 87.72  ? 297 SER A CA  1 
ATOM   2229  C  C   . SER A 1 297 ? 198.320 193.758 246.464 1.00 87.72  ? 297 SER A C   1 
ATOM   2230  O  O   . SER A 1 297 ? 198.824 193.122 245.535 1.00 87.72  ? 297 SER A O   1 
ATOM   2231  C  CB  . SER A 1 297 ? 199.307 195.181 248.289 1.00 87.72  ? 297 SER A CB  1 
ATOM   2232  O  OG  . SER A 1 297 ? 200.182 195.783 247.351 1.00 87.72  ? 297 SER A OG  1 
ATOM   2233  N  N   . HIS A 1 298 ? 197.211 194.485 246.332 1.00 84.83  ? 298 HIS A N   1 
ATOM   2234  C  CA  . HIS A 1 298 ? 196.522 194.675 245.065 1.00 84.83  ? 298 HIS A CA  1 
ATOM   2235  C  C   . HIS A 1 298 ? 196.200 196.149 244.878 1.00 84.83  ? 298 HIS A C   1 
ATOM   2236  O  O   . HIS A 1 298 ? 195.757 196.824 245.808 1.00 84.83  ? 298 HIS A O   1 
ATOM   2237  C  CB  . HIS A 1 298 ? 195.233 193.859 244.997 1.00 84.83  ? 298 HIS A CB  1 
ATOM   2238  C  CG  . HIS A 1 298 ? 194.459 194.064 243.734 1.00 84.83  ? 298 HIS A CG  1 
ATOM   2239  N  ND1 . HIS A 1 298 ? 193.561 195.096 243.571 1.00 84.83  ? 298 HIS A ND1 1 
ATOM   2240  C  CD2 . HIS A 1 298 ? 194.448 193.368 242.573 1.00 84.83  ? 298 HIS A CD2 1 
ATOM   2241  C  CE1 . HIS A 1 298 ? 193.029 195.027 242.364 1.00 84.83  ? 298 HIS A CE1 1 
ATOM   2242  N  NE2 . HIS A 1 298 ? 193.550 193.988 241.737 1.00 84.83  ? 298 HIS A NE2 1 
ATOM   2243  N  N   . VAL A 1 299 ? 196.421 196.641 243.665 1.00 78.54  ? 299 VAL A N   1 
ATOM   2244  C  CA  . VAL A 1 299 ? 196.197 198.043 243.334 1.00 78.54  ? 299 VAL A CA  1 
ATOM   2245  C  C   . VAL A 1 299 ? 195.322 198.116 242.095 1.00 78.54  ? 299 VAL A C   1 
ATOM   2246  O  O   . VAL A 1 299 ? 195.512 197.353 241.141 1.00 78.54  ? 299 VAL A O   1 
ATOM   2247  C  CB  . VAL A 1 299 ? 197.528 198.796 243.116 1.00 78.54  ? 299 VAL A CB  1 
ATOM   2248  C  CG1 . VAL A 1 299 ? 198.373 198.100 242.074 1.00 78.54  ? 299 VAL A CG1 1 
ATOM   2249  C  CG2 . VAL A 1 299 ? 197.269 200.229 242.685 1.00 78.54  ? 299 VAL A CG2 1 
ATOM   2250  N  N   . SER A 1 300 ? 194.344 199.020 242.121 1.00 72.33  ? 300 SER A N   1 
ATOM   2251  C  CA  . SER A 1 300 ? 193.478 199.257 240.976 1.00 72.33  ? 300 SER A CA  1 
ATOM   2252  C  C   . SER A 1 300 ? 193.287 200.753 240.805 1.00 72.33  ? 300 SER A C   1 
ATOM   2253  O  O   . SER A 1 300 ? 193.122 201.475 241.792 1.00 72.33  ? 300 SER A O   1 
ATOM   2254  C  CB  . SER A 1 300 ? 192.123 198.567 241.154 1.00 72.33  ? 300 SER A CB  1 
ATOM   2255  O  OG  . SER A 1 300 ? 191.290 199.306 242.028 1.00 72.33  ? 300 SER A OG  1 
ATOM   2256  N  N   . LEU A 1 301 ? 193.314 201.218 239.561 1.00 67.94  ? 301 LEU A N   1 
ATOM   2257  C  CA  . LEU A 1 301 ? 193.125 202.625 239.252 1.00 67.94  ? 301 LEU A CA  1 
ATOM   2258  C  C   . LEU A 1 301 ? 191.975 202.767 238.273 1.00 67.94  ? 301 LEU A C   1 
ATOM   2259  O  O   . LEU A 1 301 ? 191.893 202.031 237.287 1.00 67.94  ? 301 LEU A O   1 
ATOM   2260  C  CB  . LEU A 1 301 ? 194.392 203.251 238.660 1.00 67.94  ? 301 LEU A CB  1 
ATOM   2261  C  CG  . LEU A 1 301 ? 195.545 203.527 239.630 1.00 67.94  ? 301 LEU A CG  1 
ATOM   2262  C  CD1 . LEU A 1 301 ? 196.405 202.291 239.828 1.00 67.94  ? 301 LEU A CD1 1 
ATOM   2263  C  CD2 . LEU A 1 301 ? 196.393 204.697 239.167 1.00 67.94  ? 301 LEU A CD2 1 
ATOM   2264  N  N   . PHE A 1 302 ? 191.084 203.709 238.552 1.00 71.10  ? 302 PHE A N   1 
ATOM   2265  C  CA  . PHE A 1 302 ? 189.919 203.920 237.713 1.00 71.10  ? 302 PHE A CA  1 
ATOM   2266  C  C   . PHE A 1 302 ? 189.797 205.395 237.380 1.00 71.10  ? 302 PHE A C   1 
ATOM   2267  O  O   . PHE A 1 302 ? 190.004 206.249 238.245 1.00 71.10  ? 302 PHE A O   1 
ATOM   2268  C  CB  . PHE A 1 302 ? 188.641 203.446 238.406 1.00 71.10  ? 302 PHE A CB  1 
ATOM   2269  C  CG  . PHE A 1 302 ? 188.563 201.968 238.585 1.00 71.10  ? 302 PHE A CG  1 
ATOM   2270  C  CD1 . PHE A 1 302 ? 189.298 201.337 239.570 1.00 71.10  ? 302 PHE A CD1 1 
ATOM   2271  C  CD2 . PHE A 1 302 ? 187.745 201.205 237.777 1.00 71.10  ? 302 PHE A CD2 1 
ATOM   2272  C  CE1 . PHE A 1 302 ? 189.225 199.972 239.738 1.00 71.10  ? 302 PHE A CE1 1 
ATOM   2273  C  CE2 . PHE A 1 302 ? 187.668 199.838 237.940 1.00 71.10  ? 302 PHE A CE2 1 
ATOM   2274  C  CZ  . PHE A 1 302 ? 188.410 199.221 238.923 1.00 71.10  ? 302 PHE A CZ  1 
ATOM   2275  N  N   . ALA A 1 303 ? 189.445 205.688 236.135 1.00 71.97  ? 303 ALA A N   1 
ATOM   2276  C  CA  . ALA A 1 303 ? 189.126 207.040 235.716 1.00 71.97  ? 303 ALA A CA  1 
ATOM   2277  C  C   . ALA A 1 303 ? 187.616 207.230 235.699 1.00 71.97  ? 303 ALA A C   1 
ATOM   2278  O  O   . ALA A 1 303 ? 186.841 206.273 235.742 1.00 71.97  ? 303 ALA A O   1 
ATOM   2279  C  CB  . ALA A 1 303 ? 189.719 207.334 234.338 1.00 71.97  ? 303 ALA A CB  1 
ATOM   2280  N  N   . LEU A 1 304 ? 187.199 208.485 235.630 1.00 82.67  ? 304 LEU A N   1 
ATOM   2281  C  CA  . LEU A 1 304 ? 185.786 208.842 235.608 1.00 82.67  ? 304 LEU A CA  1 
ATOM   2282  C  C   . LEU A 1 304 ? 185.456 209.438 234.246 1.00 82.67  ? 304 LEU A C   1 
ATOM   2283  O  O   . LEU A 1 304 ? 185.862 210.564 233.941 1.00 82.67  ? 304 LEU A O   1 
ATOM   2284  C  CB  . LEU A 1 304 ? 185.460 209.819 236.736 1.00 82.67  ? 304 LEU A CB  1 
ATOM   2285  C  CG  . LEU A 1 304 ? 183.988 210.138 237.002 1.00 82.67  ? 304 LEU A CG  1 
ATOM   2286  C  CD1 . LEU A 1 304 ? 183.747 210.303 238.494 1.00 82.67  ? 304 LEU A CD1 1 
ATOM   2287  C  CD2 . LEU A 1 304 ? 183.562 211.395 236.257 1.00 82.67  ? 304 LEU A CD2 1 
ATOM   2288  N  N   . ARG A 1 305 ? 184.725 208.682 233.432 1.00 87.53  ? 305 ARG A N   1 
ATOM   2289  C  CA  . ARG A 1 305 ? 184.224 209.153 232.147 1.00 87.53  ? 305 ARG A CA  1 
ATOM   2290  C  C   . ARG A 1 305 ? 182.704 209.195 232.211 1.00 87.53  ? 305 ARG A C   1 
ATOM   2291  O  O   . ARG A 1 305 ? 182.065 208.178 232.504 1.00 87.53  ? 305 ARG A O   1 
ATOM   2292  C  CB  . ARG A 1 305 ? 184.688 208.250 231.003 1.00 87.53  ? 305 ARG A CB  1 
ATOM   2293  C  CG  . ARG A 1 305 ? 186.158 207.873 231.050 1.00 87.53  ? 305 ARG A CG  1 
ATOM   2294  C  CD  . ARG A 1 305 ? 187.026 208.966 230.452 1.00 87.53  ? 305 ARG A CD  1 
ATOM   2295  N  NE  . ARG A 1 305 ? 188.430 208.576 230.392 1.00 87.53  ? 305 ARG A NE  1 
ATOM   2296  C  CZ  . ARG A 1 305 ? 189.130 208.475 229.271 1.00 87.53  ? 305 ARG A CZ  1 
ATOM   2297  N  NH1 . ARG A 1 305 ? 188.588 208.731 228.092 1.00 87.53  ? 305 ARG A NH1 1 
ATOM   2298  N  NH2 . ARG A 1 305 ? 190.407 208.109 229.335 1.00 87.53  ? 305 ARG A NH2 1 
ATOM   2299  N  N   . ASN A 1 306 ? 182.134 210.370 231.948 1.00 88.64  ? 306 ASN A N   1 
ATOM   2300  C  CA  . ASN A 1 306 ? 180.688 210.585 231.938 1.00 88.64  ? 306 ASN A CA  1 
ATOM   2301  C  C   . ASN A 1 306 ? 180.029 210.205 233.261 1.00 88.64  ? 306 ASN A C   1 
ATOM   2302  O  O   . ASN A 1 306 ? 178.837 209.889 233.294 1.00 88.64  ? 306 ASN A O   1 
ATOM   2303  C  CB  . ASN A 1 306 ? 180.022 209.827 230.783 1.00 88.64  ? 306 ASN A CB  1 
ATOM   2304  C  CG  . ASN A 1 306 ? 180.637 210.158 229.437 1.00 88.64  ? 306 ASN A CG  1 
ATOM   2305  O  OD1 . ASN A 1 306 ? 181.165 211.251 229.235 1.00 88.64  ? 306 ASN A OD1 1 
ATOM   2306  N  ND2 . ASN A 1 306 ? 180.571 209.211 228.508 1.00 88.64  ? 306 ASN A ND2 1 
ATOM   2307  N  N   . GLY A 1 307 ? 180.780 210.231 234.358 1.00 85.01  ? 307 GLY A N   1 
ATOM   2308  C  CA  . GLY A 1 307 ? 180.218 209.943 235.661 1.00 85.01  ? 307 GLY A CA  1 
ATOM   2309  C  C   . GLY A 1 307 ? 180.219 208.489 236.072 1.00 85.01  ? 307 GLY A C   1 
ATOM   2310  O  O   . GLY A 1 307 ? 179.374 208.093 236.882 1.00 85.01  ? 307 GLY A O   1 
ATOM   2311  N  N   . MET A 1 308 ? 181.125 207.682 235.543 1.00 82.90  ? 308 MET A N   1 
ATOM   2312  C  CA  . MET A 1 308 ? 181.225 206.272 235.879 1.00 82.90  ? 308 MET A CA  1 
ATOM   2313  C  C   . MET A 1 308 ? 182.669 205.925 236.198 1.00 82.90  ? 308 MET A C   1 
ATOM   2314  O  O   . MET A 1 308 ? 183.594 206.608 235.747 1.00 82.90  ? 308 MET A O   1 
ATOM   2315  C  CB  . MET A 1 308 ? 180.726 205.390 234.725 1.00 82.90  ? 308 MET A CB  1 
ATOM   2316  C  CG  . MET A 1 308 ? 179.216 205.324 234.598 1.00 82.90  ? 308 MET A CG  1 
ATOM   2317  S  SD  . MET A 1 308 ? 178.531 206.733 233.710 1.00 82.90  ? 308 MET A SD  1 
ATOM   2318  C  CE  . MET A 1 308 ? 179.018 206.344 232.031 1.00 82.90  ? 308 MET A CE  1 
ATOM   2319  N  N   . PRO A 1 309 ? 182.897 204.883 236.998 1.00 77.81  ? 309 PRO A N   1 
ATOM   2320  C  CA  . PRO A 1 309 ? 184.260 204.370 237.195 1.00 77.81  ? 309 PRO A CA  1 
ATOM   2321  C  C   . PRO A 1 309 ? 184.650 203.411 236.080 1.00 77.81  ? 309 PRO A C   1 
ATOM   2322  O  O   . PRO A 1 309 ? 184.109 202.307 235.970 1.00 77.81  ? 309 PRO A O   1 
ATOM   2323  C  CB  . PRO A 1 309 ? 184.168 203.664 238.554 1.00 77.81  ? 309 PRO A CB  1 
ATOM   2324  C  CG  . PRO A 1 309 ? 182.757 203.221 238.641 1.00 77.81  ? 309 PRO A CG  1 
ATOM   2325  C  CD  . PRO A 1 309 ? 181.929 204.243 237.905 1.00 77.81  ? 309 PRO A CD  1 
ATOM   2326  N  N   . ILE A 1 310 ? 185.608 203.830 235.255 1.00 76.18  ? 310 ILE A N   1 
ATOM   2327  C  CA  . ILE A 1 310 ? 186.096 203.049 234.122 1.00 76.18  ? 310 ILE A CA  1 
ATOM   2328  C  C   . ILE A 1 310 ? 187.515 202.595 234.425 1.00 76.18  ? 310 ILE A C   1 
ATOM   2329  O  O   . ILE A 1 310 ? 188.351 203.398 234.857 1.00 76.18  ? 310 ILE A O   1 
ATOM   2330  C  CB  . ILE A 1 310 ? 186.040 203.850 232.809 1.00 76.18  ? 310 ILE A CB  1 
ATOM   2331  C  CG1 . ILE A 1 310 ? 184.591 204.093 232.387 1.00 76.18  ? 310 ILE A CG1 1 
ATOM   2332  C  CG2 . ILE A 1 310 ? 186.803 203.134 231.706 1.00 76.18  ? 310 ILE A CG2 1 
ATOM   2333  C  CD1 . ILE A 1 310 ? 183.993 205.357 232.924 1.00 76.18  ? 310 ILE A CD1 1 
ATOM   2334  N  N   . HIS A 1 311 ? 187.784 201.313 234.197 1.00 67.45  ? 311 HIS A N   1 
ATOM   2335  C  CA  . HIS A 1 311 ? 189.061 200.731 234.580 1.00 67.45  ? 311 HIS A CA  1 
ATOM   2336  C  C   . HIS A 1 311 ? 190.199 201.304 233.750 1.00 67.45  ? 311 HIS A C   1 
ATOM   2337  O  O   . HIS A 1 311 ? 190.117 201.357 232.520 1.00 67.45  ? 311 HIS A O   1 
ATOM   2338  C  CB  . HIS A 1 311 ? 189.008 199.220 234.419 1.00 67.45  ? 311 HIS A CB  1 
ATOM   2339  C  CG  . HIS A 1 311 ? 190.346 198.589 234.213 1.00 67.45  ? 311 HIS A CG  1 
ATOM   2340  N  ND1 . HIS A 1 311 ? 190.914 198.437 232.967 1.00 67.45  ? 311 HIS A ND1 1 
ATOM   2341  C  CD2 . HIS A 1 311 ? 191.225 198.059 235.095 1.00 67.45  ? 311 HIS A CD2 1 
ATOM   2342  C  CE1 . HIS A 1 311 ? 192.088 197.845 233.091 1.00 67.45  ? 311 HIS A CE1 1 
ATOM   2343  N  NE2 . HIS A 1 311 ? 192.299 197.603 234.372 1.00 67.45  ? 311 HIS A NE2 1 
ATOM   2344  N  N   . TRP A 1 312 ? 191.269 201.726 234.429 1.00 63.21  ? 312 TRP A N   1 
ATOM   2345  C  CA  . TRP A 1 312 ? 192.493 202.194 233.781 1.00 63.21  ? 312 TRP A CA  1 
ATOM   2346  C  C   . TRP A 1 312 ? 193.568 201.113 233.774 1.00 63.21  ? 312 TRP A C   1 
ATOM   2347  O  O   . TRP A 1 312 ? 194.044 200.717 232.707 1.00 63.21  ? 312 TRP A O   1 
ATOM   2348  C  CB  . TRP A 1 312 ? 193.005 203.461 234.476 1.00 63.21  ? 312 TRP A CB  1 
ATOM   2349  C  CG  . TRP A 1 312 ? 194.332 203.975 233.973 1.00 63.21  ? 312 TRP A CG  1 
ATOM   2350  C  CD1 . TRP A 1 312 ? 194.945 203.666 232.794 1.00 63.21  ? 312 TRP A CD1 1 
ATOM   2351  C  CD2 . TRP A 1 312 ? 195.201 204.901 234.642 1.00 63.21  ? 312 TRP A CD2 1 
ATOM   2352  N  NE1 . TRP A 1 312 ? 196.140 204.335 232.693 1.00 63.21  ? 312 TRP A NE1 1 
ATOM   2353  C  CE2 . TRP A 1 312 ? 196.318 205.099 233.815 1.00 63.21  ? 312 TRP A CE2 1 
ATOM   2354  C  CE3 . TRP A 1 312 ? 195.140 205.577 235.860 1.00 63.21  ? 312 TRP A CE3 1 
ATOM   2355  C  CZ2 . TRP A 1 312 ? 197.355 205.943 234.163 1.00 63.21  ? 312 TRP A CZ2 1 
ATOM   2356  C  CZ3 . TRP A 1 312 ? 196.171 206.413 236.200 1.00 63.21  ? 312 TRP A CZ3 1 
ATOM   2357  C  CH2 . TRP A 1 312 ? 197.266 206.588 235.358 1.00 63.21  ? 312 TRP A CH2 1 
ATOM   2358  N  N   . ALA A 1 313 ? 193.958 200.628 234.948 1.00 66.73  ? 313 ALA A N   1 
ATOM   2359  C  CA  . ALA A 1 313 ? 194.911 199.532 235.051 1.00 66.73  ? 313 ALA A CA  1 
ATOM   2360  C  C   . ALA A 1 313 ? 194.899 199.016 236.482 1.00 66.73  ? 313 ALA A C   1 
ATOM   2361  O  O   . ALA A 1 313 ? 194.660 199.762 237.435 1.00 66.73  ? 313 ALA A O   1 
ATOM   2362  C  CB  . ALA A 1 313 ? 196.321 199.954 234.637 1.00 66.73  ? 313 ALA A CB  1 
ATOM   2363  N  N   . SER A 1 314 ? 195.165 197.722 236.619 1.00 80.82  ? 314 SER A N   1 
ATOM   2364  C  CA  . SER A 1 314 ? 195.242 197.094 237.927 1.00 80.82  ? 314 SER A CA  1 
ATOM   2365  C  C   . SER A 1 314 ? 196.385 196.093 237.912 1.00 80.82  ? 314 SER A C   1 
ATOM   2366  O  O   . SER A 1 314 ? 196.719 195.543 236.860 1.00 80.82  ? 314 SER A O   1 
ATOM   2367  C  CB  . SER A 1 314 ? 193.925 196.401 238.296 1.00 80.82  ? 314 SER A CB  1 
ATOM   2368  O  OG  . SER A 1 314 ? 193.671 195.300 237.441 1.00 80.82  ? 314 SER A OG  1 
ATOM   2369  N  N   . SER A 1 315 ? 196.982 195.870 239.078 1.00 87.76  ? 315 SER A N   1 
ATOM   2370  C  CA  . SER A 1 315 ? 198.089 194.929 239.166 1.00 87.76  ? 315 SER A CA  1 
ATOM   2371  C  C   . SER A 1 315 ? 197.604 193.510 238.902 1.00 87.76  ? 315 SER A C   1 
ATOM   2372  O  O   . SER A 1 315 ? 196.520 193.114 239.337 1.00 87.76  ? 315 SER A O   1 
ATOM   2373  C  CB  . SER A 1 315 ? 198.752 195.010 240.537 1.00 87.76  ? 315 SER A CB  1 
ATOM   2374  O  OG  . SER A 1 315 ? 197.801 194.843 241.573 1.00 87.76  ? 315 SER A OG  1 
ATOM   2375  N  N   . SER A 1 316 ? 198.420 192.742 238.181 1.00 102.40 ? 316 SER A N   1 
ATOM   2376  C  CA  . SER A 1 316 ? 198.098 191.358 237.856 1.00 102.40 ? 316 SER A CA  1 
ATOM   2377  C  C   . SER A 1 316 ? 198.509 190.380 238.948 1.00 102.40 ? 316 SER A C   1 
ATOM   2378  O  O   . SER A 1 316 ? 198.258 189.179 238.806 1.00 102.40 ? 316 SER A O   1 
ATOM   2379  C  CB  . SER A 1 316 ? 198.764 190.960 236.536 1.00 102.40 ? 316 SER A CB  1 
ATOM   2380  O  OG  . SER A 1 316 ? 200.176 190.986 236.649 1.00 102.40 ? 316 SER A OG  1 
ATOM   2381  N  N   . HIS A 1 317 ? 199.127 190.860 240.027 1.00 107.46 ? 317 HIS A N   1 
ATOM   2382  C  CA  . HIS A 1 317 ? 199.570 189.994 241.112 1.00 107.46 ? 317 HIS A CA  1 
ATOM   2383  C  C   . HIS A 1 317 ? 198.385 189.546 241.957 1.00 107.46 ? 317 HIS A C   1 
ATOM   2384  O  O   . HIS A 1 317 ? 198.166 190.065 243.056 1.00 107.46 ? 317 HIS A O   1 
ATOM   2385  C  CB  . HIS A 1 317 ? 200.606 190.717 241.976 1.00 107.46 ? 317 HIS A CB  1 
ATOM   2386  C  CG  . HIS A 1 317 ? 201.409 189.807 242.853 1.00 107.46 ? 317 HIS A CG  1 
ATOM   2387  N  ND1 . HIS A 1 317 ? 202.383 190.271 243.710 1.00 107.46 ? 317 HIS A ND1 1 
ATOM   2388  C  CD2 . HIS A 1 317 ? 201.384 188.462 243.005 1.00 107.46 ? 317 HIS A CD2 1 
ATOM   2389  C  CE1 . HIS A 1 317 ? 202.924 189.252 244.353 1.00 107.46 ? 317 HIS A CE1 1 
ATOM   2390  N  NE2 . HIS A 1 317 ? 202.335 188.142 243.944 1.00 107.46 ? 317 HIS A NE2 1 
ATOM   2391  N  N   . GLY A 1 318 ? 197.617 188.583 241.452 1.00 116.05 ? 318 GLY A N   1 
ATOM   2392  C  CA  . GLY A 1 318 ? 196.438 188.109 242.149 1.00 116.05 ? 318 GLY A CA  1 
ATOM   2393  C  C   . GLY A 1 318 ? 196.721 187.027 243.171 1.00 116.05 ? 318 GLY A C   1 
ATOM   2394  O  O   . GLY A 1 318 ? 196.049 185.991 243.190 1.00 116.05 ? 318 GLY A O   1 
ATOM   2395  N  N   . ALA A 1 319 ? 197.714 187.255 244.026 1.00 118.86 ? 319 ALA A N   1 
ATOM   2396  C  CA  . ALA A 1 319 ? 198.037 186.297 245.070 1.00 118.86 ? 319 ALA A CA  1 
ATOM   2397  C  C   . ALA A 1 319 ? 196.956 186.294 246.146 1.00 118.86 ? 319 ALA A C   1 
ATOM   2398  O  O   . ALA A 1 319 ? 196.196 187.253 246.308 1.00 118.86 ? 319 ALA A O   1 
ATOM   2399  C  CB  . ALA A 1 319 ? 199.397 186.615 245.690 1.00 118.86 ? 319 ALA A CB  1 
ATOM   2400  N  N   . GLU A 1 320 ? 196.887 185.187 246.883 1.00 122.43 ? 320 GLU A N   1 
ATOM   2401  C  CA  . GLU A 1 320 ? 195.898 185.055 247.944 1.00 122.43 ? 320 GLU A CA  1 
ATOM   2402  C  C   . GLU A 1 320 ? 196.147 186.087 249.037 1.00 122.43 ? 320 GLU A C   1 
ATOM   2403  O  O   . GLU A 1 320 ? 197.280 186.268 249.492 1.00 122.43 ? 320 GLU A O   1 
ATOM   2404  C  CB  . GLU A 1 320 ? 195.937 183.643 248.528 1.00 122.43 ? 320 GLU A CB  1 
ATOM   2405  C  CG  . GLU A 1 320 ? 195.516 182.558 247.551 1.00 122.43 ? 320 GLU A CG  1 
ATOM   2406  C  CD  . GLU A 1 320 ? 195.490 181.181 248.185 1.00 122.43 ? 320 GLU A CD  1 
ATOM   2407  O  OE1 . GLU A 1 320 ? 195.500 181.099 249.431 1.00 122.43 ? 320 GLU A OE1 1 
ATOM   2408  O  OE2 . GLU A 1 320 ? 195.459 180.181 247.438 1.00 122.43 ? 320 GLU A OE2 1 
ATOM   2409  N  N   . ILE A 1 321 ? 195.081 186.762 249.458 1.00 115.57 ? 321 ILE A N   1 
ATOM   2410  C  CA  . ILE A 1 321 ? 195.146 187.792 250.488 1.00 115.57 ? 321 ILE A CA  1 
ATOM   2411  C  C   . ILE A 1 321 ? 194.262 187.363 251.649 1.00 115.57 ? 321 ILE A C   1 
ATOM   2412  O  O   . ILE A 1 321 ? 193.096 187.005 251.448 1.00 115.57 ? 321 ILE A O   1 
ATOM   2413  C  CB  . ILE A 1 321 ? 194.712 189.167 249.948 1.00 115.57 ? 321 ILE A CB  1 
ATOM   2414  C  CG1 . ILE A 1 321 ? 195.560 189.555 248.735 1.00 115.57 ? 321 ILE A CG1 1 
ATOM   2415  C  CG2 . ILE A 1 321 ? 194.821 190.227 251.035 1.00 115.57 ? 321 ILE A CG2 1 
ATOM   2416  C  CD1 . ILE A 1 321 ? 195.172 190.880 248.116 1.00 115.57 ? 321 ILE A CD1 1 
ATOM   2417  N  N   . GLN A 1 322 ? 194.818 187.396 252.856 1.00 116.21 ? 322 GLN A N   1 
ATOM   2418  C  CA  . GLN A 1 322 ? 194.101 187.013 254.064 1.00 116.21 ? 322 GLN A CA  1 
ATOM   2419  C  C   . GLN A 1 322 ? 193.723 188.262 254.849 1.00 116.21 ? 322 GLN A C   1 
ATOM   2420  O  O   . GLN A 1 322 ? 194.588 189.087 255.161 1.00 116.21 ? 322 GLN A O   1 
ATOM   2421  C  CB  . GLN A 1 322 ? 194.952 186.082 254.929 1.00 116.21 ? 322 GLN A CB  1 
ATOM   2422  C  CG  . GLN A 1 322 ? 195.466 184.852 254.197 1.00 116.21 ? 322 GLN A CG  1 
ATOM   2423  C  CD  . GLN A 1 322 ? 196.360 183.988 255.064 1.00 116.21 ? 322 GLN A CD  1 
ATOM   2424  O  OE1 . GLN A 1 322 ? 196.517 184.240 256.259 1.00 116.21 ? 322 GLN A OE1 1 
ATOM   2425  N  NE2 . GLN A 1 322 ? 196.953 182.962 254.465 1.00 116.21 ? 322 GLN A NE2 1 
ATOM   2426  N  N   . ASN A 1 323 ? 192.435 188.392 255.164 1.00 115.11 ? 323 ASN A N   1 
ATOM   2427  C  CA  . ASN A 1 323 ? 191.901 189.538 255.899 1.00 115.11 ? 323 ASN A CA  1 
ATOM   2428  C  C   . ASN A 1 323 ? 192.259 190.848 255.196 1.00 115.11 ? 323 ASN A C   1 
ATOM   2429  O  O   . ASN A 1 323 ? 192.986 191.696 255.717 1.00 115.11 ? 323 ASN A O   1 
ATOM   2430  C  CB  . ASN A 1 323 ? 192.388 189.533 257.350 1.00 115.11 ? 323 ASN A CB  1 
ATOM   2431  C  CG  . ASN A 1 323 ? 191.977 188.281 258.099 1.00 115.11 ? 323 ASN A CG  1 
ATOM   2432  O  OD1 . ASN A 1 323 ? 190.833 187.836 258.006 1.00 115.11 ? 323 ASN A OD1 1 
ATOM   2433  N  ND2 . ASN A 1 323 ? 192.911 187.704 258.846 1.00 115.11 ? 323 ASN A ND2 1 
ATOM   2434  N  N   . ALA A 1 324 ? 191.732 190.992 253.982 1.00 112.98 ? 324 ALA A N   1 
ATOM   2435  C  CA  . ALA A 1 324 ? 192.074 192.131 253.140 1.00 112.98 ? 324 ALA A CA  1 
ATOM   2436  C  C   . ALA A 1 324 ? 191.489 193.423 253.698 1.00 112.98 ? 324 ALA A C   1 
ATOM   2437  O  O   . ALA A 1 324 ? 190.307 193.486 254.049 1.00 112.98 ? 324 ALA A O   1 
ATOM   2438  C  CB  . ALA A 1 324 ? 191.574 191.900 251.715 1.00 112.98 ? 324 ALA A CB  1 
ATOM   2439  N  N   . GLN A 1 325 ? 192.326 194.453 253.777 1.00 107.56 ? 325 GLN A N   1 
ATOM   2440  C  CA  . GLN A 1 325 ? 191.897 195.793 254.146 1.00 107.56 ? 325 GLN A CA  1 
ATOM   2441  C  C   . GLN A 1 325 ? 191.850 196.666 252.899 1.00 107.56 ? 325 GLN A C   1 
ATOM   2442  O  O   . GLN A 1 325 ? 192.779 196.653 252.084 1.00 107.56 ? 325 GLN A O   1 
ATOM   2443  C  CB  . GLN A 1 325 ? 192.843 196.398 255.186 1.00 107.56 ? 325 GLN A CB  1 
ATOM   2444  C  CG  . GLN A 1 325 ? 192.713 197.904 255.369 1.00 107.56 ? 325 GLN A CG  1 
ATOM   2445  C  CD  . GLN A 1 325 ? 191.570 198.294 256.289 1.00 107.56 ? 325 GLN A CD  1 
ATOM   2446  O  OE1 . GLN A 1 325 ? 190.623 197.532 256.485 1.00 107.56 ? 325 GLN A OE1 1 
ATOM   2447  N  NE2 . GLN A 1 325 ? 191.656 199.489 256.862 1.00 107.56 ? 325 GLN A NE2 1 
ATOM   2448  N  N   . SER A 1 326 ? 190.762 197.421 252.755 1.00 100.46 ? 326 SER A N   1 
ATOM   2449  C  CA  . SER A 1 326 ? 190.468 198.161 251.537 1.00 100.46 ? 326 SER A CA  1 
ATOM   2450  C  C   . SER A 1 326 ? 190.589 199.660 251.771 1.00 100.46 ? 326 SER A C   1 
ATOM   2451  O  O   . SER A 1 326 ? 190.217 200.175 252.830 1.00 100.46 ? 326 SER A O   1 
ATOM   2452  C  CB  . SER A 1 326 ? 189.057 197.841 251.027 1.00 100.46 ? 326 SER A CB  1 
ATOM   2453  O  OG  . SER A 1 326 ? 188.908 196.457 250.764 1.00 100.46 ? 326 SER A OG  1 
ATOM   2454  N  N   . TRP A 1 327 ? 191.117 200.356 250.765 1.00 85.23  ? 327 TRP A N   1 
ATOM   2455  C  CA  . TRP A 1 327 ? 191.182 201.811 250.784 1.00 85.23  ? 327 TRP A CA  1 
ATOM   2456  C  C   . TRP A 1 327 ? 190.792 202.343 249.415 1.00 85.23  ? 327 TRP A C   1 
ATOM   2457  O  O   . TRP A 1 327 ? 191.214 201.811 248.387 1.00 85.23  ? 327 TRP A O   1 
ATOM   2458  C  CB  . TRP A 1 327 ? 192.575 202.317 251.159 1.00 85.23  ? 327 TRP A CB  1 
ATOM   2459  C  CG  . TRP A 1 327 ? 192.749 203.777 250.914 1.00 85.23  ? 327 TRP A CG  1 
ATOM   2460  C  CD1 . TRP A 1 327 ? 193.644 204.363 250.071 1.00 85.23  ? 327 TRP A CD1 1 
ATOM   2461  C  CD2 . TRP A 1 327 ? 192.011 204.844 251.522 1.00 85.23  ? 327 TRP A CD2 1 
ATOM   2462  N  NE1 . TRP A 1 327 ? 193.510 205.729 250.113 1.00 85.23  ? 327 TRP A NE1 1 
ATOM   2463  C  CE2 . TRP A 1 327 ? 192.514 206.050 250.997 1.00 85.23  ? 327 TRP A CE2 1 
ATOM   2464  C  CE3 . TRP A 1 327 ? 190.975 204.897 252.461 1.00 85.23  ? 327 TRP A CE3 1 
ATOM   2465  C  CZ2 . TRP A 1 327 ? 192.016 207.295 251.378 1.00 85.23  ? 327 TRP A CZ2 1 
ATOM   2466  C  CZ3 . TRP A 1 327 ? 190.482 206.134 252.836 1.00 85.23  ? 327 TRP A CZ3 1 
ATOM   2467  C  CH2 . TRP A 1 327 ? 191.003 207.316 252.296 1.00 85.23  ? 327 TRP A CH2 1 
ATOM   2468  N  N   . SER A 1 328 ? 189.996 203.412 249.413 1.00 85.58  ? 328 SER A N   1 
ATOM   2469  C  CA  . SER A 1 328 ? 189.464 203.970 248.167 1.00 85.58  ? 328 SER A CA  1 
ATOM   2470  C  C   . SER A 1 328 ? 189.566 205.494 248.249 1.00 85.58  ? 328 SER A C   1 
ATOM   2471  O  O   . SER A 1 328 ? 188.698 206.158 248.817 1.00 85.58  ? 328 SER A O   1 
ATOM   2472  C  CB  . SER A 1 328 ? 188.032 203.516 247.926 1.00 85.58  ? 328 SER A CB  1 
ATOM   2473  O  OG  . SER A 1 328 ? 187.577 203.916 246.645 1.00 85.58  ? 328 SER A OG  1 
ATOM   2474  N  N   . ALA A 1 329 ? 190.631 206.033 247.668 1.00 78.79  ? 329 ALA A N   1 
ATOM   2475  C  CA  . ALA A 1 329 ? 190.834 207.470 247.614 1.00 78.79  ? 329 ALA A CA  1 
ATOM   2476  C  C   . ALA A 1 329 ? 190.360 208.017 246.277 1.00 78.79  ? 329 ALA A C   1 
ATOM   2477  O  O   . ALA A 1 329 ? 190.636 207.448 245.215 1.00 78.79  ? 329 ALA A O   1 
ATOM   2478  C  CB  . ALA A 1 329 ? 192.306 207.824 247.827 1.00 78.79  ? 329 ALA A CB  1 
ATOM   2479  N  N   . THR A 1 330 ? 189.637 209.133 246.343 1.00 82.33  ? 330 THR A N   1 
ATOM   2480  C  CA  . THR A 1 330 ? 189.055 209.775 245.170 1.00 82.33  ? 330 THR A CA  1 
ATOM   2481  C  C   . THR A 1 330 ? 190.037 210.811 244.638 1.00 82.33  ? 330 THR A C   1 
ATOM   2482  O  O   . THR A 1 330 ? 190.073 211.949 245.116 1.00 82.33  ? 330 THR A O   1 
ATOM   2483  C  CB  . THR A 1 330 ? 187.714 210.425 245.503 1.00 82.33  ? 330 THR A CB  1 
ATOM   2484  O  OG1 . THR A 1 330 ? 187.930 211.571 246.336 1.00 82.33  ? 330 THR A OG1 1 
ATOM   2485  C  CG2 . THR A 1 330 ? 186.812 209.442 246.231 1.00 82.33  ? 330 THR A CG2 1 
ATOM   2486  N  N   . ILE A 1 331 ? 190.829 210.408 243.647 1.00 79.84  ? 331 ILE A N   1 
ATOM   2487  C  CA  . ILE A 1 331 ? 191.690 211.342 242.940 1.00 79.84  ? 331 ILE A CA  1 
ATOM   2488  C  C   . ILE A 1 331 ? 190.821 212.377 242.254 1.00 79.84  ? 331 ILE A C   1 
ATOM   2489  O  O   . ILE A 1 331 ? 189.854 212.032 241.567 1.00 79.84  ? 331 ILE A O   1 
ATOM   2490  C  CB  . ILE A 1 331 ? 192.568 210.585 241.930 1.00 79.84  ? 331 ILE A CB  1 
ATOM   2491  C  CG1 . ILE A 1 331 ? 193.328 209.455 242.624 1.00 79.84  ? 331 ILE A CG1 1 
ATOM   2492  C  CG2 . ILE A 1 331 ? 193.526 211.533 241.251 1.00 79.84  ? 331 ILE A CG2 1 
ATOM   2493  C  CD1 . ILE A 1 331 ? 193.798 208.371 241.679 1.00 79.84  ? 331 ILE A CD1 1 
ATOM   2494  N  N   . ARG A 1 332 ? 191.167 213.649 242.425 1.00 87.19  ? 332 ARG A N   1 
ATOM   2495  C  CA  . ARG A 1 332 ? 190.321 214.744 241.976 1.00 87.19  ? 332 ARG A CA  1 
ATOM   2496  C  C   . ARG A 1 332 ? 191.075 215.626 240.993 1.00 87.19  ? 332 ARG A C   1 
ATOM   2497  O  O   . ARG A 1 332 ? 192.306 215.711 241.038 1.00 87.19  ? 332 ARG A O   1 
ATOM   2498  C  CB  . ARG A 1 332 ? 189.830 215.575 243.167 1.00 87.19  ? 332 ARG A CB  1 
ATOM   2499  C  CG  . ARG A 1 332 ? 188.914 214.802 244.101 1.00 87.19  ? 332 ARG A CG  1 
ATOM   2500  C  CD  . ARG A 1 332 ? 188.525 215.618 245.318 1.00 87.19  ? 332 ARG A CD  1 
ATOM   2501  N  NE  . ARG A 1 332 ? 187.721 214.838 246.251 1.00 87.19  ? 332 ARG A NE  1 
ATOM   2502  C  CZ  . ARG A 1 332 ? 186.395 214.822 246.265 1.00 87.19  ? 332 ARG A CZ  1 
ATOM   2503  N  NH1 . ARG A 1 332 ? 185.686 215.534 245.404 1.00 87.19  ? 332 ARG A NH1 1 
ATOM   2504  N  NH2 . ARG A 1 332 ? 185.765 214.072 247.164 1.00 87.19  ? 332 ARG A NH2 1 
ATOM   2505  N  N   . GLN A 1 333 ? 190.325 216.282 240.110 1.00 90.03  ? 333 GLN A N   1 
ATOM   2506  C  CA  . GLN A 1 333 ? 190.909 217.164 239.111 1.00 90.03  ? 333 GLN A CA  1 
ATOM   2507  C  C   . GLN A 1 333 ? 191.395 218.460 239.759 1.00 90.03  ? 333 GLN A C   1 
ATOM   2508  O  O   . GLN A 1 333 ? 191.358 218.637 240.980 1.00 90.03  ? 333 GLN A O   1 
ATOM   2509  C  CB  . GLN A 1 333 ? 189.896 217.469 238.011 1.00 90.03  ? 333 GLN A CB  1 
ATOM   2510  C  CG  . GLN A 1 333 ? 189.647 216.331 237.044 1.00 90.03  ? 333 GLN A CG  1 
ATOM   2511  C  CD  . GLN A 1 333 ? 188.622 216.682 235.984 1.00 90.03  ? 333 GLN A CD  1 
ATOM   2512  O  OE1 . GLN A 1 333 ? 188.040 217.766 236.001 1.00 90.03  ? 333 GLN A OE1 1 
ATOM   2513  N  NE2 . GLN A 1 333 ? 188.396 215.763 235.052 1.00 90.03  ? 333 GLN A NE2 1 
ATOM   2514  N  N   . ARG A 1 334 ? 191.864 219.379 238.912 1.00 94.43  ? 334 ARG A N   1 
ATOM   2515  C  CA  . ARG A 1 334 ? 192.313 220.680 239.399 1.00 94.43  ? 334 ARG A CA  1 
ATOM   2516  C  C   . ARG A 1 334 ? 191.165 221.458 240.031 1.00 94.43  ? 334 ARG A C   1 
ATOM   2517  O  O   . ARG A 1 334 ? 191.340 222.102 241.072 1.00 94.43  ? 334 ARG A O   1 
ATOM   2518  C  CB  . ARG A 1 334 ? 192.940 221.479 238.256 1.00 94.43  ? 334 ARG A CB  1 
ATOM   2519  C  CG  . ARG A 1 334 ? 193.424 222.868 238.645 1.00 94.43  ? 334 ARG A CG  1 
ATOM   2520  C  CD  . ARG A 1 334 ? 194.578 222.807 239.634 1.00 94.43  ? 334 ARG A CD  1 
ATOM   2521  N  NE  . ARG A 1 334 ? 194.130 222.953 241.014 1.00 94.43  ? 334 ARG A NE  1 
ATOM   2522  C  CZ  . ARG A 1 334 ? 194.940 223.069 242.057 1.00 94.43  ? 334 ARG A CZ  1 
ATOM   2523  N  NH1 . ARG A 1 334 ? 196.255 223.062 241.914 1.00 94.43  ? 334 ARG A NH1 1 
ATOM   2524  N  NH2 . ARG A 1 334 ? 194.418 223.198 243.273 1.00 94.43  ? 334 ARG A NH2 1 
ATOM   2525  N  N   . ASP A 1 335 ? 189.982 221.408 239.418 1.00 95.54  ? 335 ASP A N   1 
ATOM   2526  C  CA  . ASP A 1 335 ? 188.822 222.107 239.953 1.00 95.54  ? 335 ASP A CA  1 
ATOM   2527  C  C   . ASP A 1 335 ? 188.282 221.473 241.228 1.00 95.54  ? 335 ASP A C   1 
ATOM   2528  O  O   . ASP A 1 335 ? 187.440 222.085 241.894 1.00 95.54  ? 335 ASP A O   1 
ATOM   2529  C  CB  . ASP A 1 335 ? 187.711 222.172 238.899 1.00 95.54  ? 335 ASP A CB  1 
ATOM   2530  C  CG  . ASP A 1 335 ? 187.314 220.803 238.380 1.00 95.54  ? 335 ASP A CG  1 
ATOM   2531  O  OD1 . ASP A 1 335 ? 187.902 219.797 238.827 1.00 95.54  ? 335 ASP A OD1 1 
ATOM   2532  O  OD2 . ASP A 1 335 ? 186.409 220.734 237.522 1.00 95.54  ? 335 ASP A OD2 1 
ATOM   2533  N  N   . GLY A 1 336 ? 188.740 220.274 241.582 1.00 89.42  ? 336 GLY A N   1 
ATOM   2534  C  CA  . GLY A 1 336 ? 188.301 219.602 242.784 1.00 89.42  ? 336 GLY A CA  1 
ATOM   2535  C  C   . GLY A 1 336 ? 187.244 218.541 242.572 1.00 89.42  ? 336 GLY A C   1 
ATOM   2536  O  O   . GLY A 1 336 ? 186.972 217.771 243.502 1.00 89.42  ? 336 GLY A O   1 
ATOM   2537  N  N   . ALA A 1 337 ? 186.641 218.478 241.393 1.00 87.52  ? 337 ALA A N   1 
ATOM   2538  C  CA  . ALA A 1 337 ? 185.653 217.445 241.132 1.00 87.52  ? 337 ALA A CA  1 
ATOM   2539  C  C   . ALA A 1 337 ? 186.327 216.075 241.134 1.00 87.52  ? 337 ALA A C   1 
ATOM   2540  O  O   . ALA A 1 337 ? 187.464 215.943 240.665 1.00 87.52  ? 337 ALA A O   1 
ATOM   2541  C  CB  . ALA A 1 337 ? 184.960 217.690 239.792 1.00 87.52  ? 337 ALA A CB  1 
ATOM   2542  N  N   . PRO A 1 338 ? 185.669 215.043 241.661 1.00 86.51  ? 338 PRO A N   1 
ATOM   2543  C  CA  . PRO A 1 338 ? 186.264 213.703 241.630 1.00 86.51  ? 338 PRO A CA  1 
ATOM   2544  C  C   . PRO A 1 338 ? 186.495 213.244 240.201 1.00 86.51  ? 338 PRO A C   1 
ATOM   2545  O  O   . PRO A 1 338 ? 185.681 213.489 239.310 1.00 86.51  ? 338 PRO A O   1 
ATOM   2546  C  CB  . PRO A 1 338 ? 185.222 212.834 242.343 1.00 86.51  ? 338 PRO A CB  1 
ATOM   2547  C  CG  . PRO A 1 338 ? 183.949 213.587 242.220 1.00 86.51  ? 338 PRO A CG  1 
ATOM   2548  C  CD  . PRO A 1 338 ? 184.330 215.037 242.271 1.00 86.51  ? 338 PRO A CD  1 
ATOM   2549  N  N   . ALA A 1 339 ? 187.622 212.571 239.991 1.00 83.30  ? 339 ALA A N   1 
ATOM   2550  C  CA  . ALA A 1 339 ? 188.009 212.146 238.657 1.00 83.30  ? 339 ALA A CA  1 
ATOM   2551  C  C   . ALA A 1 339 ? 188.482 210.705 238.588 1.00 83.30  ? 339 ALA A C   1 
ATOM   2552  O  O   . ALA A 1 339 ? 188.588 210.168 237.483 1.00 83.30  ? 339 ALA A O   1 
ATOM   2553  C  CB  . ALA A 1 339 ? 189.113 213.058 238.108 1.00 83.30  ? 339 ALA A CB  1 
ATOM   2554  N  N   . GLY A 1 340 ? 188.776 210.066 239.710 1.00 76.99  ? 340 GLY A N   1 
ATOM   2555  C  CA  . GLY A 1 340 ? 189.256 208.702 239.661 1.00 76.99  ? 340 GLY A CA  1 
ATOM   2556  C  C   . GLY A 1 340 ? 189.320 208.098 241.043 1.00 76.99  ? 340 GLY A C   1 
ATOM   2557  O  O   . GLY A 1 340 ? 189.146 208.774 242.054 1.00 76.99  ? 340 GLY A O   1 
ATOM   2558  N  N   . ILE A 1 341 ? 189.588 206.801 241.059 1.00 72.48  ? 341 ILE A N   1 
ATOM   2559  C  CA  . ILE A 1 341 ? 189.633 206.017 242.287 1.00 72.48  ? 341 ILE A CA  1 
ATOM   2560  C  C   . ILE A 1 341 ? 190.928 205.226 242.310 1.00 72.48  ? 341 ILE A C   1 
ATOM   2561  O  O   . ILE A 1 341 ? 191.253 204.524 241.347 1.00 72.48  ? 341 ILE A O   1 
ATOM   2562  C  CB  . ILE A 1 341 ? 188.425 205.067 242.402 1.00 72.48  ? 341 ILE A CB  1 
ATOM   2563  C  CG1 . ILE A 1 341 ? 187.130 205.861 242.568 1.00 72.48  ? 341 ILE A CG1 1 
ATOM   2564  C  CG2 . ILE A 1 341 ? 188.619 204.098 243.547 1.00 72.48  ? 341 ILE A CG2 1 
ATOM   2565  C  CD1 . ILE A 1 341 ? 186.995 206.534 243.916 1.00 72.48  ? 341 ILE A CD1 1 
ATOM   2566  N  N   . LEU A 1 342 ? 191.669 205.336 243.407 1.00 71.97  ? 342 LEU A N   1 
ATOM   2567  C  CA  . LEU A 1 342 ? 192.884 204.548 243.598 1.00 71.97  ? 342 LEU A CA  1 
ATOM   2568  C  C   . LEU A 1 342 ? 192.612 203.599 244.757 1.00 71.97  ? 342 LEU A C   1 
ATOM   2569  O  O   . LEU A 1 342 ? 192.723 203.972 245.926 1.00 71.97  ? 342 LEU A O   1 
ATOM   2570  C  CB  . LEU A 1 342 ? 194.094 205.433 243.846 1.00 71.97  ? 342 LEU A CB  1 
ATOM   2571  C  CG  . LEU A 1 342 ? 195.384 204.747 244.290 1.00 71.97  ? 342 LEU A CG  1 
ATOM   2572  C  CD1 . LEU A 1 342 ? 195.787 203.668 243.323 1.00 71.97  ? 342 LEU A CD1 1 
ATOM   2573  C  CD2 . LEU A 1 342 ? 196.486 205.775 244.423 1.00 71.97  ? 342 LEU A CD2 1 
ATOM   2574  N  N   . GLN A 1 343 ? 192.248 202.368 244.424 1.00 77.90  ? 343 GLN A N   1 
ATOM   2575  C  CA  . GLN A 1 343 ? 191.782 201.396 245.398 1.00 77.90  ? 343 GLN A CA  1 
ATOM   2576  C  C   . GLN A 1 343 ? 192.890 200.398 245.701 1.00 77.90  ? 343 GLN A C   1 
ATOM   2577  O  O   . GLN A 1 343 ? 193.476 199.810 244.785 1.00 77.90  ? 343 GLN A O   1 
ATOM   2578  C  CB  . GLN A 1 343 ? 190.537 200.684 244.871 1.00 77.90  ? 343 GLN A CB  1 
ATOM   2579  C  CG  . GLN A 1 343 ? 190.119 199.457 245.641 1.00 77.90  ? 343 GLN A CG  1 
ATOM   2580  C  CD  . GLN A 1 343 ? 188.883 198.816 245.050 1.00 77.90  ? 343 GLN A CD  1 
ATOM   2581  O  OE1 . GLN A 1 343 ? 188.916 198.286 243.940 1.00 77.90  ? 343 GLN A OE1 1 
ATOM   2582  N  NE2 . GLN A 1 343 ? 187.781 198.863 245.788 1.00 77.90  ? 343 GLN A NE2 1 
ATOM   2583  N  N   . ILE A 1 344 ? 193.173 200.213 246.986 1.00 83.57  ? 344 ILE A N   1 
ATOM   2584  C  CA  . ILE A 1 344 ? 194.257 199.353 247.443 1.00 83.57  ? 344 ILE A CA  1 
ATOM   2585  C  C   . ILE A 1 344 ? 193.688 198.293 248.372 1.00 83.57  ? 344 ILE A C   1 
ATOM   2586  O  O   . ILE A 1 344 ? 192.906 198.602 249.278 1.00 83.57  ? 344 ILE A O   1 
ATOM   2587  C  CB  . ILE A 1 344 ? 195.358 200.150 248.168 1.00 83.57  ? 344 ILE A CB  1 
ATOM   2588  C  CG1 . ILE A 1 344 ? 195.869 201.288 247.293 1.00 83.57  ? 344 ILE A CG1 1 
ATOM   2589  C  CG2 . ILE A 1 344 ? 196.506 199.231 248.518 1.00 83.57  ? 344 ILE A CG2 1 
ATOM   2590  C  CD1 . ILE A 1 344 ? 196.503 200.827 246.026 1.00 83.57  ? 344 ILE A CD1 1 
ATOM   2591  N  N   . LYS A 1 345 ? 194.083 197.047 248.142 1.00 89.52  ? 345 LYS A N   1 
ATOM   2592  C  CA  . LYS A 1 345 ? 193.793 195.938 249.036 1.00 89.52  ? 345 LYS A CA  1 
ATOM   2593  C  C   . LYS A 1 345 ? 195.103 195.454 249.632 1.00 89.52  ? 345 LYS A C   1 
ATOM   2594  O  O   . LYS A 1 345 ? 196.047 195.146 248.901 1.00 89.52  ? 345 LYS A O   1 
ATOM   2595  C  CB  . LYS A 1 345 ? 193.101 194.786 248.302 1.00 89.52  ? 345 LYS A CB  1 
ATOM   2596  C  CG  . LYS A 1 345 ? 191.878 195.188 247.499 1.00 89.52  ? 345 LYS A CG  1 
ATOM   2597  C  CD  . LYS A 1 345 ? 190.657 195.333 248.385 1.00 89.52  ? 345 LYS A CD  1 
ATOM   2598  C  CE  . LYS A 1 345 ? 190.071 193.978 248.745 1.00 89.52  ? 345 LYS A CE  1 
ATOM   2599  N  NZ  . LYS A 1 345 ? 188.806 194.109 249.520 1.00 89.52  ? 345 LYS A NZ  1 
ATOM   2600  N  N   . THR A 1 346 ? 195.161 195.388 250.958 1.00 105.12 ? 346 THR A N   1 
ATOM   2601  C  CA  . THR A 1 346 ? 196.394 195.015 251.636 1.00 105.12 ? 346 THR A CA  1 
ATOM   2602  C  C   . THR A 1 346 ? 196.133 193.861 252.592 1.00 105.12 ? 346 THR A C   1 
ATOM   2603  O  O   . THR A 1 346 ? 195.032 193.712 253.128 1.00 105.12 ? 346 THR A O   1 
ATOM   2604  C  CB  . THR A 1 346 ? 197.009 196.202 252.396 1.00 105.12 ? 346 THR A CB  1 
ATOM   2605  O  OG1 . THR A 1 346 ? 198.270 195.813 252.956 1.00 105.12 ? 346 THR A OG1 1 
ATOM   2606  C  CG2 . THR A 1 346 ? 196.085 196.671 253.510 1.00 105.12 ? 346 THR A CG2 1 
ATOM   2607  N  N   . SER A 1 347 ? 197.156 193.034 252.786 1.00 110.47 ? 347 SER A N   1 
ATOM   2608  C  CA  . SER A 1 347 ? 197.063 191.942 253.743 1.00 110.47 ? 347 SER A CA  1 
ATOM   2609  C  C   . SER A 1 347 ? 197.115 192.481 255.168 1.00 110.47 ? 347 SER A C   1 
ATOM   2610  O  O   . SER A 1 347 ? 197.695 193.537 255.438 1.00 110.47 ? 347 SER A O   1 
ATOM   2611  C  CB  . SER A 1 347 ? 198.192 190.936 253.520 1.00 110.47 ? 347 SER A CB  1 
ATOM   2612  O  OG  . SER A 1 347 ? 198.124 190.371 252.222 1.00 110.47 ? 347 SER A OG  1 
ATOM   2613  N  N   . SER A 1 348 ? 196.494 191.744 256.085 1.00 115.16 ? 348 SER A N   1 
ATOM   2614  C  CA  . SER A 1 348 ? 196.455 192.169 257.478 1.00 115.16 ? 348 SER A CA  1 
ATOM   2615  C  C   . SER A 1 348 ? 197.839 192.069 258.106 1.00 115.16 ? 348 SER A C   1 
ATOM   2616  O  O   . SER A 1 348 ? 198.439 190.991 258.155 1.00 115.16 ? 348 SER A O   1 
ATOM   2617  C  CB  . SER A 1 348 ? 195.454 191.319 258.260 1.00 115.16 ? 348 SER A CB  1 
ATOM   2618  O  OG  . SER A 1 348 ? 195.704 189.936 258.075 1.00 115.16 ? 348 SER A OG  1 
ATOM   2619  N  N   . GLY A 1 349 ? 198.345 193.203 258.587 1.00 112.43 ? 349 GLY A N   1 
ATOM   2620  C  CA  . GLY A 1 349 ? 199.642 193.252 259.228 1.00 112.43 ? 349 GLY A CA  1 
ATOM   2621  C  C   . GLY A 1 349 ? 200.829 193.332 258.296 1.00 112.43 ? 349 GLY A C   1 
ATOM   2622  O  O   . GLY A 1 349 ? 201.967 193.383 258.777 1.00 112.43 ? 349 GLY A O   1 
ATOM   2623  N  N   . ALA A 1 350 ? 200.610 193.343 256.979 1.00 104.37 ? 350 ALA A N   1 
ATOM   2624  C  CA  . ALA A 1 350 ? 201.731 193.407 256.047 1.00 104.37 ? 350 ALA A CA  1 
ATOM   2625  C  C   . ALA A 1 350 ? 202.348 194.801 256.013 1.00 104.37 ? 350 ALA A C   1 
ATOM   2626  O  O   . ALA A 1 350 ? 203.576 194.942 256.007 1.00 104.37 ? 350 ALA A O   1 
ATOM   2627  C  CB  . ALA A 1 350 ? 201.278 192.986 254.650 1.00 104.37 ? 350 ALA A CB  1 
ATOM   2628  N  N   . GLU A 1 351 ? 201.515 195.839 255.992 1.00 95.16  ? 351 GLU A N   1 
ATOM   2629  C  CA  . GLU A 1 351 ? 201.992 197.212 255.933 1.00 95.16  ? 351 GLU A CA  1 
ATOM   2630  C  C   . GLU A 1 351 ? 201.227 198.052 256.945 1.00 95.16  ? 351 GLU A C   1 
ATOM   2631  O  O   . GLU A 1 351 ? 200.097 197.734 257.321 1.00 95.16  ? 351 GLU A O   1 
ATOM   2632  C  CB  . GLU A 1 351 ? 201.839 197.808 254.526 1.00 95.16  ? 351 GLU A CB  1 
ATOM   2633  C  CG  . GLU A 1 351 ? 202.527 197.009 253.428 1.00 95.16  ? 351 GLU A CG  1 
ATOM   2634  C  CD  . GLU A 1 351 ? 204.040 197.115 253.480 1.00 95.16  ? 351 GLU A CD  1 
ATOM   2635  O  OE1 . GLU A 1 351 ? 204.556 198.024 254.163 1.00 95.16  ? 351 GLU A OE1 1 
ATOM   2636  O  OE2 . GLU A 1 351 ? 204.715 196.285 252.835 1.00 95.16  ? 351 GLU A OE2 1 
ATOM   2637  N  N   . THR A 1 352 ? 201.860 199.134 257.381 1.00 82.05  ? 352 THR A N   1 
ATOM   2638  C  CA  . THR A 1 352 ? 201.264 199.997 258.385 1.00 82.05  ? 352 THR A CA  1 
ATOM   2639  C  C   . THR A 1 352 ? 200.285 200.977 257.745 1.00 82.05  ? 352 THR A C   1 
ATOM   2640  O  O   . THR A 1 352 ? 200.333 201.257 256.543 1.00 82.05  ? 352 THR A O   1 
ATOM   2641  C  CB  . THR A 1 352 ? 202.345 200.761 259.148 1.00 82.05  ? 352 THR A CB  1 
ATOM   2642  O  OG1 . THR A 1 352 ? 202.758 201.899 258.384 1.00 82.05  ? 352 THR A OG1 1 
ATOM   2643  C  CG2 . THR A 1 352 ? 203.546 199.864 259.398 1.00 82.05  ? 352 THR A CG2 1 
ATOM   2644  N  N   . SER A 1 353 ? 199.381 201.498 258.578 1.00 79.07  ? 353 SER A N   1 
ATOM   2645  C  CA  . SER A 1 353 ? 198.369 202.428 258.091 1.00 79.07  ? 353 SER A CA  1 
ATOM   2646  C  C   . SER A 1 353 ? 199.001 203.703 257.550 1.00 79.07  ? 353 SER A C   1 
ATOM   2647  O  O   . SER A 1 353 ? 198.605 204.198 256.489 1.00 79.07  ? 353 SER A O   1 
ATOM   2648  C  CB  . SER A 1 353 ? 197.377 202.755 259.207 1.00 79.07  ? 353 SER A CB  1 
ATOM   2649  O  OG  . SER A 1 353 ? 196.393 203.672 258.762 1.00 79.07  ? 353 SER A OG  1 
ATOM   2650  N  N   . ALA A 1 354 ? 199.990 204.246 258.263 1.00 77.93  ? 354 ALA A N   1 
ATOM   2651  C  CA  . ALA A 1 354 ? 200.666 205.448 257.784 1.00 77.93  ? 354 ALA A CA  1 
ATOM   2652  C  C   . ALA A 1 354 ? 201.372 205.189 256.460 1.00 77.93  ? 354 ALA A C   1 
ATOM   2653  O  O   . ALA A 1 354 ? 201.305 206.013 255.540 1.00 77.93  ? 354 ALA A O   1 
ATOM   2654  C  CB  . ALA A 1 354 ? 201.656 205.948 258.834 1.00 77.93  ? 354 ALA A CB  1 
ATOM   2655  N  N   . PHE A 1 355 ? 202.044 204.042 256.342 1.00 73.93  ? 355 PHE A N   1 
ATOM   2656  C  CA  . PHE A 1 355 ? 202.741 203.706 255.105 1.00 73.93  ? 355 PHE A CA  1 
ATOM   2657  C  C   . PHE A 1 355 ? 201.774 203.603 253.937 1.00 73.93  ? 355 PHE A C   1 
ATOM   2658  O  O   . PHE A 1 355 ? 202.012 204.176 252.865 1.00 73.93  ? 355 PHE A O   1 
ATOM   2659  C  CB  . PHE A 1 355 ? 203.501 202.394 255.276 1.00 73.93  ? 355 PHE A CB  1 
ATOM   2660  C  CG  . PHE A 1 355 ? 204.304 202.003 254.077 1.00 73.93  ? 355 PHE A CG  1 
ATOM   2661  C  CD1 . PHE A 1 355 ? 205.496 202.639 253.789 1.00 73.93  ? 355 PHE A CD1 1 
ATOM   2662  C  CD2 . PHE A 1 355 ? 203.867 200.998 253.235 1.00 73.93  ? 355 PHE A CD2 1 
ATOM   2663  C  CE1 . PHE A 1 355 ? 206.240 202.277 252.685 1.00 73.93  ? 355 PHE A CE1 1 
ATOM   2664  C  CE2 . PHE A 1 355 ? 204.606 200.632 252.130 1.00 73.93  ? 355 PHE A CE2 1 
ATOM   2665  C  CZ  . PHE A 1 355 ? 205.794 201.273 251.855 1.00 73.93  ? 355 PHE A CZ  1 
ATOM   2666  N  N   . ILE A 1 356 ? 200.674 202.873 254.121 1.00 70.93  ? 356 ILE A N   1 
ATOM   2667  C  CA  . ILE A 1 356 ? 199.750 202.672 253.010 1.00 70.93  ? 356 ILE A CA  1 
ATOM   2668  C  C   . ILE A 1 356 ? 199.068 203.984 252.646 1.00 70.93  ? 356 ILE A C   1 
ATOM   2669  O  O   . ILE A 1 356 ? 198.853 204.281 251.465 1.00 70.93  ? 356 ILE A O   1 
ATOM   2670  C  CB  . ILE A 1 356 ? 198.734 201.560 253.330 1.00 70.93  ? 356 ILE A CB  1 
ATOM   2671  C  CG1 . ILE A 1 356 ? 197.824 201.324 252.126 1.00 70.93  ? 356 ILE A CG1 1 
ATOM   2672  C  CG2 . ILE A 1 356 ? 197.896 201.896 254.545 1.00 70.93  ? 356 ILE A CG2 1 
ATOM   2673  C  CD1 . ILE A 1 356 ? 198.566 200.813 250.917 1.00 70.93  ? 356 ILE A CD1 1 
ATOM   2674  N  N   . GLU A 1 357 ? 198.747 204.808 253.647 1.00 70.27  ? 357 GLU A N   1 
ATOM   2675  C  CA  . GLU A 1 357 ? 198.132 206.098 253.361 1.00 70.27  ? 357 GLU A CA  1 
ATOM   2676  C  C   . GLU A 1 357 ? 199.084 207.004 252.593 1.00 70.27  ? 357 GLU A C   1 
ATOM   2677  O  O   . GLU A 1 357 ? 198.678 207.682 251.641 1.00 70.27  ? 357 GLU A O   1 
ATOM   2678  C  CB  . GLU A 1 357 ? 197.685 206.766 254.660 1.00 70.27  ? 357 GLU A CB  1 
ATOM   2679  C  CG  . GLU A 1 357 ? 196.354 206.260 255.190 1.00 70.27  ? 357 GLU A CG  1 
ATOM   2680  C  CD  . GLU A 1 357 ? 195.166 206.950 254.546 1.00 70.27  ? 357 GLU A CD  1 
ATOM   2681  O  OE1 . GLU A 1 357 ? 195.381 207.853 253.710 1.00 70.27  ? 357 GLU A OE1 1 
ATOM   2682  O  OE2 . GLU A 1 357 ? 194.017 206.587 254.874 1.00 70.27  ? 357 GLU A OE2 1 
ATOM   2683  N  N   . ARG A 1 358 ? 200.357 207.028 252.990 1.00 62.78  ? 358 ARG A N   1 
ATOM   2684  C  CA  . ARG A 1 358 ? 201.324 207.865 252.292 1.00 62.78  ? 358 ARG A CA  1 
ATOM   2685  C  C   . ARG A 1 358 ? 201.531 207.399 250.856 1.00 62.78  ? 358 ARG A C   1 
ATOM   2686  O  O   . ARG A 1 358 ? 201.599 208.223 249.932 1.00 62.78  ? 358 ARG A O   1 
ATOM   2687  C  CB  . ARG A 1 358 ? 202.649 207.869 253.048 1.00 62.78  ? 358 ARG A CB  1 
ATOM   2688  C  CG  . ARG A 1 358 ? 203.336 209.206 253.052 1.00 62.78  ? 358 ARG A CG  1 
ATOM   2689  C  CD  . ARG A 1 358 ? 204.825 209.037 253.184 1.00 62.78  ? 358 ARG A CD  1 
ATOM   2690  N  NE  . ARG A 1 358 ? 205.515 210.312 253.057 1.00 62.78  ? 358 ARG A NE  1 
ATOM   2691  C  CZ  . ARG A 1 358 ? 206.813 210.434 252.834 1.00 62.78  ? 358 ARG A CZ  1 
ATOM   2692  N  NH1 . ARG A 1 358 ? 207.591 209.374 252.697 1.00 62.78  ? 358 ARG A NH1 1 
ATOM   2693  N  NH2 . ARG A 1 358 ? 207.344 211.649 252.739 1.00 62.78  ? 358 ARG A NH2 1 
ATOM   2694  N  N   . VAL A 1 359 ? 201.644 206.085 250.648 1.00 58.57  ? 359 VAL A N   1 
ATOM   2695  C  CA  . VAL A 1 359 ? 201.814 205.567 249.294 1.00 58.57  ? 359 VAL A CA  1 
ATOM   2696  C  C   . VAL A 1 359 ? 200.594 205.898 248.450 1.00 58.57  ? 359 VAL A C   1 
ATOM   2697  O  O   . VAL A 1 359 ? 200.712 206.270 247.274 1.00 58.57  ? 359 VAL A O   1 
ATOM   2698  C  CB  . VAL A 1 359 ? 202.085 204.054 249.329 1.00 58.57  ? 359 VAL A CB  1 
ATOM   2699  C  CG1 . VAL A 1 359 ? 202.033 203.480 247.940 1.00 58.57  ? 359 VAL A CG1 1 
ATOM   2700  C  CG2 . VAL A 1 359 ? 203.415 203.776 249.961 1.00 58.57  ? 359 VAL A CG2 1 
ATOM   2701  N  N   . ALA A 1 360 ? 199.403 205.775 249.037 1.00 59.34  ? 360 ALA A N   1 
ATOM   2702  C  CA  . ALA A 1 360 ? 198.186 206.115 248.315 1.00 59.34  ? 360 ALA A CA  1 
ATOM   2703  C  C   . ALA A 1 360 ? 198.184 207.579 247.914 1.00 59.34  ? 360 ALA A C   1 
ATOM   2704  O  O   . ALA A 1 360 ? 197.808 207.923 246.793 1.00 59.34  ? 360 ALA A O   1 
ATOM   2705  C  CB  . ALA A 1 360 ? 196.962 205.788 249.168 1.00 59.34  ? 360 ALA A CB  1 
ATOM   2706  N  N   . ASP A 1 361 ? 198.602 208.461 248.820 1.00 59.74  ? 361 ASP A N   1 
ATOM   2707  C  CA  . ASP A 1 361 ? 198.613 209.885 248.503 1.00 59.74  ? 361 ASP A CA  1 
ATOM   2708  C  C   . ASP A 1 361 ? 199.607 210.204 247.388 1.00 59.74  ? 361 ASP A C   1 
ATOM   2709  O  O   . ASP A 1 361 ? 199.293 210.969 246.462 1.00 59.74  ? 361 ASP A O   1 
ATOM   2710  C  CB  . ASP A 1 361 ? 198.932 210.687 249.760 1.00 59.74  ? 361 ASP A CB  1 
ATOM   2711  C  CG  . ASP A 1 361 ? 198.450 212.111 249.674 1.00 59.74  ? 361 ASP A CG  1 
ATOM   2712  O  OD1 . ASP A 1 361 ? 197.457 212.359 248.962 1.00 59.74  ? 361 ASP A OD1 1 
ATOM   2713  O  OD2 . ASP A 1 361 ? 199.060 212.985 250.323 1.00 59.74  ? 361 ASP A OD2 1 
ATOM   2714  N  N   . ILE A 1 362 ? 200.807 209.623 247.452 1.00 58.07  ? 362 ILE A N   1 
ATOM   2715  C  CA  . ILE A 1 362 ? 201.812 209.871 246.415 1.00 58.07  ? 362 ILE A CA  1 
ATOM   2716  C  C   . ILE A 1 362 ? 201.299 209.401 245.059 1.00 58.07  ? 362 ILE A C   1 
ATOM   2717  O  O   . ILE A 1 362 ? 201.310 210.146 244.064 1.00 58.07  ? 362 ILE A O   1 
ATOM   2718  C  CB  . ILE A 1 362 ? 203.136 209.179 246.775 1.00 58.07  ? 362 ILE A CB  1 
ATOM   2719  C  CG1 . ILE A 1 362 ? 203.734 209.802 248.026 1.00 58.07  ? 362 ILE A CG1 1 
ATOM   2720  C  CG2 . ILE A 1 362 ? 204.115 209.282 245.625 1.00 58.07  ? 362 ILE A CG2 1 
ATOM   2721  C  CD1 . ILE A 1 362 ? 204.216 211.196 247.815 1.00 58.07  ? 362 ILE A CD1 1 
ATOM   2722  N  N   . SER A 1 363 ? 200.827 208.158 245.004 1.00 56.61  ? 363 SER A N   1 
ATOM   2723  C  CA  . SER A 1 363 ? 200.329 207.642 243.743 1.00 56.61  ? 363 SER A CA  1 
ATOM   2724  C  C   . SER A 1 363 ? 199.089 208.378 243.274 1.00 56.61  ? 363 SER A C   1 
ATOM   2725  O  O   . SER A 1 363 ? 198.864 208.464 242.066 1.00 56.61  ? 363 SER A O   1 
ATOM   2726  C  CB  . SER A 1 363 ? 200.048 206.151 243.862 1.00 56.61  ? 363 SER A CB  1 
ATOM   2727  O  OG  . SER A 1 363 ? 201.195 205.484 244.339 1.00 56.61  ? 363 SER A OG  1 
ATOM   2728  N  N   . GLN A 1 364 ? 198.286 208.928 244.182 1.00 61.61  ? 364 GLN A N   1 
ATOM   2729  C  CA  . GLN A 1 364 ? 197.083 209.615 243.741 1.00 61.61  ? 364 GLN A CA  1 
ATOM   2730  C  C   . GLN A 1 364 ? 197.433 210.965 243.143 1.00 61.61  ? 364 GLN A C   1 
ATOM   2731  O  O   . GLN A 1 364 ? 196.785 211.415 242.197 1.00 61.61  ? 364 GLN A O   1 
ATOM   2732  C  CB  . GLN A 1 364 ? 196.079 209.754 244.890 1.00 61.61  ? 364 GLN A CB  1 
ATOM   2733  C  CG  . GLN A 1 364 ? 196.311 210.900 245.841 1.00 61.61  ? 364 GLN A CG  1 
ATOM   2734  C  CD  . GLN A 1 364 ? 195.559 212.148 245.434 1.00 61.61  ? 364 GLN A CD  1 
ATOM   2735  O  OE1 . GLN A 1 364 ? 194.503 212.072 244.806 1.00 61.61  ? 364 GLN A OE1 1 
ATOM   2736  N  NE2 . GLN A 1 364 ? 196.099 213.308 245.790 1.00 61.61  ? 364 GLN A NE2 1 
ATOM   2737  N  N   . HIS A 1 365 ? 198.488 211.609 243.642 1.00 59.60  ? 365 HIS A N   1 
ATOM   2738  C  CA  . HIS A 1 365 ? 198.950 212.824 242.973 1.00 59.60  ? 365 HIS A CA  1 
ATOM   2739  C  C   . HIS A 1 365 ? 199.518 212.520 241.586 1.00 59.60  ? 365 HIS A C   1 
ATOM   2740  O  O   . HIS A 1 365 ? 199.218 213.228 240.606 1.00 59.60  ? 365 HIS A O   1 
ATOM   2741  C  CB  . HIS A 1 365 ? 199.976 213.544 243.837 1.00 59.60  ? 365 HIS A CB  1 
ATOM   2742  C  CG  . HIS A 1 365 ? 199.402 214.686 244.611 1.00 59.60  ? 365 HIS A CG  1 
ATOM   2743  N  ND1 . HIS A 1 365 ? 199.126 215.907 244.037 1.00 59.60  ? 365 HIS A ND1 1 
ATOM   2744  C  CD2 . HIS A 1 365 ? 199.023 214.785 245.906 1.00 59.60  ? 365 HIS A CD2 1 
ATOM   2745  C  CE1 . HIS A 1 365 ? 198.617 216.716 244.950 1.00 59.60  ? 365 HIS A CE1 1 
ATOM   2746  N  NE2 . HIS A 1 365 ? 198.543 216.058 246.092 1.00 59.60  ? 365 HIS A NE2 1 
ATOM   2747  N  N   . MET A 1 366 ? 200.341 211.470 241.479 1.00 57.00  ? 366 MET A N   1 
ATOM   2748  C  CA  . MET A 1 366 ? 200.874 211.101 240.166 1.00 57.00  ? 366 MET A CA  1 
ATOM   2749  C  C   . MET A 1 366 ? 199.749 210.771 239.194 1.00 57.00  ? 366 MET A C   1 
ATOM   2750  O  O   . MET A 1 366 ? 199.728 211.250 238.049 1.00 57.00  ? 366 MET A O   1 
ATOM   2751  C  CB  . MET A 1 366 ? 201.824 209.913 240.291 1.00 57.00  ? 366 MET A CB  1 
ATOM   2752  C  CG  . MET A 1 366 ? 202.964 210.116 241.257 1.00 57.00  ? 366 MET A CG  1 
ATOM   2753  S  SD  . MET A 1 366 ? 203.730 211.733 241.125 1.00 57.00  ? 366 MET A SD  1 
ATOM   2754  C  CE  . MET A 1 366 ? 205.027 211.536 242.338 1.00 57.00  ? 366 MET A CE  1 
ATOM   2755  N  N   . ALA A 1 367 ? 198.792 209.959 239.640 1.00 57.63  ? 367 ALA A N   1 
ATOM   2756  C  CA  . ALA A 1 367 ? 197.656 209.621 238.801 1.00 57.63  ? 367 ALA A CA  1 
ATOM   2757  C  C   . ALA A 1 367 ? 196.820 210.848 238.482 1.00 57.63  ? 367 ALA A C   1 
ATOM   2758  O  O   . ALA A 1 367 ? 196.219 210.923 237.408 1.00 57.63  ? 367 ALA A O   1 
ATOM   2759  C  CB  . ALA A 1 367 ? 196.802 208.556 239.484 1.00 57.63  ? 367 ALA A CB  1 
ATOM   2760  N  N   . ALA A 1 368 ? 196.772 211.818 239.393 1.00 59.96  ? 368 ALA A N   1 
ATOM   2761  C  CA  . ALA A 1 368 ? 196.016 213.034 239.134 1.00 59.96  ? 368 ALA A CA  1 
ATOM   2762  C  C   . ALA A 1 368 ? 196.597 213.783 237.952 1.00 59.96  ? 368 ALA A C   1 
ATOM   2763  O  O   . ALA A 1 368 ? 195.865 214.208 237.048 1.00 59.96  ? 368 ALA A O   1 
ATOM   2764  C  CB  . ALA A 1 368 ? 196.006 213.922 240.379 1.00 59.96  ? 368 ALA A CB  1 
ATOM   2765  N  N   . LEU A 1 369 ? 197.917 213.952 237.934 1.00 60.89  ? 369 LEU A N   1 
ATOM   2766  C  CA  . LEU A 1 369 ? 198.498 214.669 236.801 1.00 60.89  ? 369 LEU A CA  1 
ATOM   2767  C  C   . LEU A 1 369 ? 198.374 213.856 235.515 1.00 60.89  ? 369 LEU A C   1 
ATOM   2768  O  O   . LEU A 1 369 ? 198.125 214.416 234.436 1.00 60.89  ? 369 LEU A O   1 
ATOM   2769  C  CB  . LEU A 1 369 ? 199.952 215.046 237.068 1.00 60.89  ? 369 LEU A CB  1 
ATOM   2770  C  CG  . LEU A 1 369 ? 200.408 216.082 236.032 1.00 60.89  ? 369 LEU A CG  1 
ATOM   2771  C  CD1 . LEU A 1 369 ? 199.417 217.240 235.963 1.00 60.89  ? 369 LEU A CD1 1 
ATOM   2772  C  CD2 . LEU A 1 369 ? 201.791 216.604 236.334 1.00 60.89  ? 369 LEU A CD2 1 
ATOM   2773  N  N   . ALA A 1 370 ? 198.533 212.533 235.606 1.00 56.82  ? 370 ALA A N   1 
ATOM   2774  C  CA  . ALA A 1 370 ? 198.371 211.709 234.413 1.00 56.82  ? 370 ALA A CA  1 
ATOM   2775  C  C   . ALA A 1 370 ? 196.968 211.847 233.843 1.00 56.82  ? 370 ALA A C   1 
ATOM   2776  O  O   . ALA A 1 370 ? 196.790 211.959 232.624 1.00 56.82  ? 370 ALA A O   1 
ATOM   2777  C  CB  . ALA A 1 370 ? 198.677 210.250 234.731 1.00 56.82  ? 370 ALA A CB  1 
ATOM   2778  N  N   . LEU A 1 371 ? 195.956 211.858 234.711 1.00 59.29  ? 371 LEU A N   1 
ATOM   2779  C  CA  . LEU A 1 371 ? 194.581 212.004 234.247 1.00 59.29  ? 371 LEU A CA  1 
ATOM   2780  C  C   . LEU A 1 371 ? 194.306 213.396 233.711 1.00 59.29  ? 371 LEU A C   1 
ATOM   2781  O  O   . LEU A 1 371 ? 193.499 213.546 232.792 1.00 59.29  ? 371 LEU A O   1 
ATOM   2782  C  CB  . LEU A 1 371 ? 193.597 211.675 235.363 1.00 59.29  ? 371 LEU A CB  1 
ATOM   2783  C  CG  . LEU A 1 371 ? 193.073 210.245 235.389 1.00 59.29  ? 371 LEU A CG  1 
ATOM   2784  C  CD1 . LEU A 1 371 ? 192.265 210.000 234.140 1.00 59.29  ? 371 LEU A CD1 1 
ATOM   2785  C  CD2 . LEU A 1 371 ? 194.199 209.239 235.507 1.00 59.29  ? 371 LEU A CD2 1 
ATOM   2786  N  N   . GLU A 1 372 ? 194.934 214.426 234.277 1.00 67.05  ? 372 GLU A N   1 
ATOM   2787  C  CA  . GLU A 1 372 ? 194.796 215.759 233.697 1.00 67.05  ? 372 GLU A CA  1 
ATOM   2788  C  C   . GLU A 1 372 ? 195.317 215.776 232.266 1.00 67.05  ? 372 GLU A C   1 
ATOM   2789  O  O   . GLU A 1 372 ? 194.659 216.296 231.352 1.00 67.05  ? 372 GLU A O   1 
ATOM   2790  C  CB  . GLU A 1 372 ? 195.536 216.786 234.553 1.00 67.05  ? 372 GLU A CB  1 
ATOM   2791  C  CG  . GLU A 1 372 ? 194.817 217.161 235.836 1.00 67.05  ? 372 GLU A CG  1 
ATOM   2792  C  CD  . GLU A 1 372 ? 193.577 217.994 235.581 1.00 67.05  ? 372 GLU A CD  1 
ATOM   2793  O  OE1 . GLU A 1 372 ? 193.574 218.777 234.609 1.00 67.05  ? 372 GLU A OE1 1 
ATOM   2794  O  OE2 . GLU A 1 372 ? 192.605 217.867 236.354 1.00 67.05  ? 372 GLU A OE2 1 
ATOM   2795  N  N   . GLN A 1 373 ? 196.494 215.184 232.050 1.00 61.89  ? 373 GLN A N   1 
ATOM   2796  C  CA  . GLN A 1 373 ? 197.025 215.075 230.694 1.00 61.89  ? 373 GLN A CA  1 
ATOM   2797  C  C   . GLN A 1 373 ? 196.064 214.318 229.791 1.00 61.89  ? 373 GLN A C   1 
ATOM   2798  O  O   . GLN A 1 373 ? 195.803 214.727 228.655 1.00 61.89  ? 373 GLN A O   1 
ATOM   2799  C  CB  . GLN A 1 373 ? 198.381 214.375 230.708 1.00 61.89  ? 373 GLN A CB  1 
ATOM   2800  C  CG  . GLN A 1 373 ? 199.564 215.286 230.889 1.00 61.89  ? 373 GLN A CG  1 
ATOM   2801  C  CD  . GLN A 1 373 ? 200.845 214.630 230.446 1.00 61.89  ? 373 GLN A CD  1 
ATOM   2802  O  OE1 . GLN A 1 373 ? 200.847 213.472 230.033 1.00 61.89  ? 373 GLN A OE1 1 
ATOM   2803  N  NE2 . GLN A 1 373 ? 201.948 215.365 230.524 1.00 61.89  ? 373 GLN A NE2 1 
ATOM   2804  N  N   . GLU A 1 374 ? 195.542 213.195 230.279 1.00 63.63  ? 374 GLU A N   1 
ATOM   2805  C  CA  . GLU A 1 374 ? 194.682 212.363 229.447 1.00 63.63  ? 374 GLU A CA  1 
ATOM   2806  C  C   . GLU A 1 374 ? 193.397 213.089 229.083 1.00 63.63  ? 374 GLU A C   1 
ATOM   2807  O  O   . GLU A 1 374 ? 192.916 212.983 227.951 1.00 63.63  ? 374 GLU A O   1 
ATOM   2808  C  CB  . GLU A 1 374 ? 194.376 211.054 230.163 1.00 63.63  ? 374 GLU A CB  1 
ATOM   2809  C  CG  . GLU A 1 374 ? 193.581 210.078 229.334 1.00 63.63  ? 374 GLU A CG  1 
ATOM   2810  C  CD  . GLU A 1 374 ? 194.452 209.243 228.428 1.00 63.63  ? 374 GLU A CD  1 
ATOM   2811  O  OE1 . GLU A 1 374 ? 195.597 209.653 228.152 1.00 63.63  ? 374 GLU A OE1 1 
ATOM   2812  O  OE2 . GLU A 1 374 ? 193.989 208.172 227.986 1.00 63.63  ? 374 GLU A OE2 1 
ATOM   2813  N  N   . LYS A 1 375 ? 192.821 213.822 230.031 1.00 63.36  ? 375 LYS A N   1 
ATOM   2814  C  CA  . LYS A 1 375 ? 191.595 214.554 229.750 1.00 63.36  ? 375 LYS A CA  1 
ATOM   2815  C  C   . LYS A 1 375 ? 191.842 215.695 228.780 1.00 63.36  ? 375 LYS A C   1 
ATOM   2816  O  O   . LYS A 1 375 ? 190.979 215.995 227.947 1.00 63.36  ? 375 LYS A O   1 
ATOM   2817  C  CB  . LYS A 1 375 ? 190.985 215.082 231.045 1.00 63.36  ? 375 LYS A CB  1 
ATOM   2818  C  CG  . LYS A 1 375 ? 189.542 215.517 230.903 1.00 63.36  ? 375 LYS A CG  1 
ATOM   2819  C  CD  . LYS A 1 375 ? 188.682 214.371 230.413 1.00 63.36  ? 375 LYS A CD  1 
ATOM   2820  C  CE  . LYS A 1 375 ? 187.205 214.668 230.606 1.00 63.36  ? 375 LYS A CE  1 
ATOM   2821  N  NZ  . LYS A 1 375 ? 186.771 215.863 229.831 1.00 63.36  ? 375 LYS A NZ  1 
ATOM   2822  N  N   . SER A 1 376 ? 193.001 216.349 228.871 1.00 63.59  ? 376 SER A N   1 
ATOM   2823  C  CA  . SER A 1 376 ? 193.341 217.353 227.869 1.00 63.59  ? 376 SER A CA  1 
ATOM   2824  C  C   . SER A 1 376 ? 193.470 216.720 226.490 1.00 63.59  ? 376 SER A C   1 
ATOM   2825  O  O   . SER A 1 376 ? 192.964 217.254 225.498 1.00 63.59  ? 376 SER A O   1 
ATOM   2826  C  CB  . SER A 1 376 ? 194.634 218.068 228.259 1.00 63.59  ? 376 SER A CB  1 
ATOM   2827  O  OG  . SER A 1 376 ? 195.005 219.017 227.276 1.00 63.59  ? 376 SER A OG  1 
ATOM   2828  N  N   . ARG A 1 377 ? 194.134 215.566 226.417 1.00 67.97  ? 377 ARG A N   1 
ATOM   2829  C  CA  . ARG A 1 377 ? 194.366 214.911 225.133 1.00 67.97  ? 377 ARG A CA  1 
ATOM   2830  C  C   . ARG A 1 377 ? 193.063 214.434 224.507 1.00 67.97  ? 377 ARG A C   1 
ATOM   2831  O  O   . ARG A 1 377 ? 192.882 214.512 223.288 1.00 67.97  ? 377 ARG A O   1 
ATOM   2832  C  CB  . ARG A 1 377 ? 195.331 213.741 225.317 1.00 67.97  ? 377 ARG A CB  1 
ATOM   2833  C  CG  . ARG A 1 377 ? 195.594 212.940 224.056 1.00 67.97  ? 377 ARG A CG  1 
ATOM   2834  C  CD  . ARG A 1 377 ? 196.436 213.729 223.071 1.00 67.97  ? 377 ARG A CD  1 
ATOM   2835  N  NE  . ARG A 1 377 ? 197.787 213.959 223.569 1.00 67.97  ? 377 ARG A NE  1 
ATOM   2836  C  CZ  . ARG A 1 377 ? 198.652 214.805 223.026 1.00 67.97  ? 377 ARG A CZ  1 
ATOM   2837  N  NH1 . ARG A 1 377 ? 198.339 215.523 221.960 1.00 67.97  ? 377 ARG A NH1 1 
ATOM   2838  N  NH2 . ARG A 1 377 ? 199.860 214.934 223.566 1.00 67.97  ? 377 ARG A NH2 1 
ATOM   2839  N  N   . GLN A 1 378 ? 192.145 213.926 225.328 1.00 70.04  ? 378 GLN A N   1 
ATOM   2840  C  CA  . GLN A 1 378 ? 190.949 213.288 224.790 1.00 70.04  ? 378 GLN A CA  1 
ATOM   2841  C  C   . GLN A 1 378 ? 190.016 214.288 224.126 1.00 70.04  ? 378 GLN A C   1 
ATOM   2842  O  O   . GLN A 1 378 ? 189.226 213.913 223.253 1.00 70.04  ? 378 GLN A O   1 
ATOM   2843  C  CB  . GLN A 1 378 ? 190.212 212.538 225.900 1.00 70.04  ? 378 GLN A CB  1 
ATOM   2844  C  CG  . GLN A 1 378 ? 190.791 211.172 226.220 1.00 70.04  ? 378 GLN A CG  1 
ATOM   2845  C  CD  . GLN A 1 378 ? 190.235 210.083 225.329 1.00 70.04  ? 378 GLN A CD  1 
ATOM   2846  O  OE1 . GLN A 1 378 ? 189.359 210.331 224.501 1.00 70.04  ? 378 GLN A OE1 1 
ATOM   2847  N  NE2 . GLN A 1 378 ? 190.742 208.867 225.492 1.00 70.04  ? 378 GLN A NE2 1 
ATOM   2848  N  N   . HIS A 1 379 ? 190.078 215.555 224.530 1.00 70.59  ? 379 HIS A N   1 
ATOM   2849  C  CA  . HIS A 1 379 ? 189.166 216.547 223.973 1.00 70.59  ? 379 HIS A CA  1 
ATOM   2850  C  C   . HIS A 1 379 ? 189.407 216.745 222.483 1.00 70.59  ? 379 HIS A C   1 
ATOM   2851  O  O   . HIS A 1 379 ? 188.458 216.890 221.705 1.00 70.59  ? 379 HIS A O   1 
ATOM   2852  C  CB  . HIS A 1 379 ? 189.324 217.869 224.724 1.00 70.59  ? 379 HIS A CB  1 
ATOM   2853  C  CG  . HIS A 1 379 ? 188.260 218.873 224.413 1.00 70.59  ? 379 HIS A CG  1 
ATOM   2854  N  ND1 . HIS A 1 379 ? 188.332 220.184 224.831 1.00 70.59  ? 379 HIS A ND1 1 
ATOM   2855  C  CD2 . HIS A 1 379 ? 187.097 218.759 223.730 1.00 70.59  ? 379 HIS A CD2 1 
ATOM   2856  C  CE1 . HIS A 1 379 ? 187.260 220.836 224.416 1.00 70.59  ? 379 HIS A CE1 1 
ATOM   2857  N  NE2 . HIS A 1 379 ? 186.495 219.994 223.746 1.00 70.59  ? 379 HIS A NE2 1 
ATOM   2858  N  N   . ILE A 1 380 ? 190.672 216.740 222.068 1.00 63.61  ? 380 ILE A N   1 
ATOM   2859  C  CA  . ILE A 1 380 ? 191.051 217.081 220.701 1.00 63.61  ? 380 ILE A CA  1 
ATOM   2860  C  C   . ILE A 1 380 ? 191.441 215.871 219.873 1.00 63.61  ? 380 ILE A C   1 
ATOM   2861  O  O   . ILE A 1 380 ? 191.906 216.046 218.735 1.00 63.61  ? 380 ILE A O   1 
ATOM   2862  C  CB  . ILE A 1 380 ? 192.201 218.107 220.688 1.00 63.61  ? 380 ILE A CB  1 
ATOM   2863  C  CG1 . ILE A 1 380 ? 193.434 217.504 221.357 1.00 63.61  ? 380 ILE A CG1 1 
ATOM   2864  C  CG2 . ILE A 1 380 ? 191.784 219.367 221.407 1.00 63.61  ? 380 ILE A CG2 1 
ATOM   2865  C  CD1 . ILE A 1 380 ? 194.611 218.441 221.433 1.00 63.61  ? 380 ILE A CD1 1 
ATOM   2866  N  N   . GLU A 1 381 ? 191.278 214.654 220.396 1.00 65.05  ? 381 GLU A N   1 
ATOM   2867  C  CA  . GLU A 1 381 ? 191.761 213.473 219.692 1.00 65.05  ? 381 GLU A CA  1 
ATOM   2868  C  C   . GLU A 1 381 ? 190.970 213.185 218.427 1.00 65.05  ? 381 GLU A C   1 
ATOM   2869  O  O   . GLU A 1 381 ? 191.516 212.593 217.492 1.00 65.05  ? 381 GLU A O   1 
ATOM   2870  C  CB  . GLU A 1 381 ? 191.725 212.256 220.616 1.00 65.05  ? 381 GLU A CB  1 
ATOM   2871  C  CG  . GLU A 1 381 ? 192.557 211.079 220.127 1.00 65.05  ? 381 GLU A CG  1 
ATOM   2872  C  CD  . GLU A 1 381 ? 194.041 211.395 220.057 1.00 65.05  ? 381 GLU A CD  1 
ATOM   2873  O  OE1 . GLU A 1 381 ? 194.506 212.264 220.824 1.00 65.05  ? 381 GLU A OE1 1 
ATOM   2874  O  OE2 . GLU A 1 381 ? 194.743 210.773 219.232 1.00 65.05  ? 381 GLU A OE2 1 
ATOM   2875  N  N   . GLN A 1 382 ? 189.707 213.587 218.370 1.00 64.32  ? 382 GLN A N   1 
ATOM   2876  C  CA  . GLN A 1 382 ? 188.866 213.332 217.210 1.00 64.32  ? 382 GLN A CA  1 
ATOM   2877  C  C   . GLN A 1 382 ? 188.834 214.503 216.239 1.00 64.32  ? 382 GLN A C   1 
ATOM   2878  O  O   . GLN A 1 382 ? 188.071 214.469 215.270 1.00 64.32  ? 382 GLN A O   1 
ATOM   2879  C  CB  . GLN A 1 382 ? 187.445 212.987 217.657 1.00 64.32  ? 382 GLN A CB  1 
ATOM   2880  C  CG  . GLN A 1 382 ? 187.369 211.817 218.624 1.00 64.32  ? 382 GLN A CG  1 
ATOM   2881  C  CD  . GLN A 1 382 ? 187.788 210.504 217.992 1.00 64.32  ? 382 GLN A CD  1 
ATOM   2882  O  OE1 . GLN A 1 382 ? 187.710 210.333 216.776 1.00 64.32  ? 382 GLN A OE1 1 
ATOM   2883  N  NE2 . GLN A 1 382 ? 188.237 209.567 218.820 1.00 64.32  ? 382 GLN A NE2 1 
ATOM   2884  N  N   . LEU A 1 383 ? 189.628 215.534 216.477 1.00 58.78  ? 383 LEU A N   1 
ATOM   2885  C  CA  . LEU A 1 383 ? 189.617 216.723 215.639 1.00 58.78  ? 383 LEU A CA  1 
ATOM   2886  C  C   . LEU A 1 383 ? 190.936 216.977 214.932 1.00 58.78  ? 383 LEU A C   1 
ATOM   2887  O  O   . LEU A 1 383 ? 190.934 217.349 213.757 1.00 58.78  ? 383 LEU A O   1 
ATOM   2888  C  CB  . LEU A 1 383 ? 189.245 217.957 216.472 1.00 58.78  ? 383 LEU A CB  1 
ATOM   2889  C  CG  . LEU A 1 383 ? 187.760 218.278 216.677 1.00 58.78  ? 383 LEU A CG  1 
ATOM   2890  C  CD1 . LEU A 1 383 ? 187.088 218.566 215.341 1.00 58.78  ? 383 LEU A CD1 1 
ATOM   2891  C  CD2 . LEU A 1 383 ? 187.021 217.182 217.435 1.00 58.78  ? 383 LEU A CD2 1 
ATOM   2892  N  N   . ILE A 1 384 ? 192.069 216.786 215.611 1.00 55.56  ? 384 ILE A N   1 
ATOM   2893  C  CA  . ILE A 1 384 ? 193.357 217.055 214.987 1.00 55.56  ? 384 ILE A CA  1 
ATOM   2894  C  C   . ILE A 1 384 ? 193.651 216.010 213.921 1.00 55.56  ? 384 ILE A C   1 
ATOM   2895  O  O   . ILE A 1 384 ? 193.489 214.803 214.140 1.00 55.56  ? 384 ILE A O   1 
ATOM   2896  C  CB  . ILE A 1 384 ? 194.465 217.096 216.049 1.00 55.56  ? 384 ILE A CB  1 
ATOM   2897  C  CG1 . ILE A 1 384 ? 194.371 218.385 216.856 1.00 55.56  ? 384 ILE A CG1 1 
ATOM   2898  C  CG2 . ILE A 1 384 ? 195.820 217.010 215.411 1.00 55.56  ? 384 ILE A CG2 1 
ATOM   2899  C  CD1 . ILE A 1 384 ? 195.409 218.488 217.946 1.00 55.56  ? 384 ILE A CD1 1 
ATOM   2900  N  N   . GLN A 1 385 ? 194.083 216.479 212.748 1.00 54.21  ? 385 GLN A N   1 
ATOM   2901  C  CA  . GLN A 1 385 ? 194.403 215.605 211.626 1.00 54.21  ? 385 GLN A CA  1 
ATOM   2902  C  C   . GLN A 1 385 ? 195.808 215.021 211.727 1.00 54.21  ? 385 GLN A C   1 
ATOM   2903  O  O   . GLN A 1 385 ? 195.997 213.821 211.515 1.00 54.21  ? 385 GLN A O   1 
ATOM   2904  C  CB  . GLN A 1 385 ? 194.253 216.366 210.309 1.00 54.21  ? 385 GLN A CB  1 
ATOM   2905  C  CG  . GLN A 1 385 ? 192.867 216.913 210.071 1.00 54.21  ? 385 GLN A CG  1 
ATOM   2906  C  CD  . GLN A 1 385 ? 191.871 215.834 209.729 1.00 54.21  ? 385 GLN A CD  1 
ATOM   2907  O  OE1 . GLN A 1 385 ? 192.006 215.149 208.718 1.00 54.21  ? 385 GLN A OE1 1 
ATOM   2908  N  NE2 . GLN A 1 385 ? 190.856 215.679 210.568 1.00 54.21  ? 385 GLN A NE2 1 
ATOM   2909  N  N   . PHE A 1 386 ? 196.798 215.847 212.044 1.00 54.70  ? 386 PHE A N   1 
ATOM   2910  C  CA  . PHE A 1 386 ? 198.169 215.374 212.113 1.00 54.70  ? 386 PHE A CA  1 
ATOM   2911  C  C   . PHE A 1 386 ? 198.398 214.575 213.393 1.00 54.70  ? 386 PHE A C   1 
ATOM   2912  O  O   . PHE A 1 386 ? 197.597 214.601 214.328 1.00 54.70  ? 386 PHE A O   1 
ATOM   2913  C  CB  . PHE A 1 386 ? 199.142 216.545 212.040 1.00 54.70  ? 386 PHE A CB  1 
ATOM   2914  C  CG  . PHE A 1 386 ? 199.553 216.903 210.642 1.00 54.70  ? 386 PHE A CG  1 
ATOM   2915  C  CD1 . PHE A 1 386 ? 198.608 217.033 209.640 1.00 54.70  ? 386 PHE A CD1 1 
ATOM   2916  C  CD2 . PHE A 1 386 ? 200.886 217.096 210.327 1.00 54.70  ? 386 PHE A CD2 1 
ATOM   2917  C  CE1 . PHE A 1 386 ? 198.982 217.358 208.353 1.00 54.70  ? 386 PHE A CE1 1 
ATOM   2918  C  CE2 . PHE A 1 386 ? 201.267 217.424 209.042 1.00 54.70  ? 386 PHE A CE2 1 
ATOM   2919  C  CZ  . PHE A 1 386 ? 200.313 217.554 208.053 1.00 54.70  ? 386 PHE A CZ  1 
ATOM   2920  N  N   . ASP A 1 387 ? 199.504 213.836 213.419 1.00 58.02  ? 387 ASP A N   1 
ATOM   2921  C  CA  . ASP A 1 387 ? 199.930 213.085 214.601 1.00 58.02  ? 387 ASP A CA  1 
ATOM   2922  C  C   . ASP A 1 387 ? 201.181 213.736 215.170 1.00 58.02  ? 387 ASP A C   1 
ATOM   2923  O  O   . ASP A 1 387 ? 202.236 213.747 214.511 1.00 58.02  ? 387 ASP A O   1 
ATOM   2924  C  CB  . ASP A 1 387 ? 200.191 211.619 214.265 1.00 58.02  ? 387 ASP A CB  1 
ATOM   2925  C  CG  . ASP A 1 387 ? 200.383 210.759 215.501 1.00 58.02  ? 387 ASP A CG  1 
ATOM   2926  O  OD1 . ASP A 1 387 ? 201.120 211.176 216.417 1.00 58.02  ? 387 ASP A OD1 1 
ATOM   2927  O  OD2 . ASP A 1 387 ? 199.802 209.655 215.556 1.00 58.02  ? 387 ASP A OD2 1 
ATOM   2928  N  N   . PRO A 1 388 ? 201.122 214.284 216.382 1.00 59.11  ? 388 PRO A N   1 
ATOM   2929  C  CA  . PRO A 1 388 ? 202.224 215.133 216.854 1.00 59.11  ? 388 PRO A CA  1 
ATOM   2930  C  C   . PRO A 1 388 ? 203.479 214.381 217.262 1.00 59.11  ? 388 PRO A C   1 
ATOM   2931  O  O   . PRO A 1 388 ? 204.509 215.025 217.487 1.00 59.11  ? 388 PRO A O   1 
ATOM   2932  C  CB  . PRO A 1 388 ? 201.602 215.871 218.047 1.00 59.11  ? 388 PRO A CB  1 
ATOM   2933  C  CG  . PRO A 1 388 ? 200.547 214.944 218.541 1.00 59.11  ? 388 PRO A CG  1 
ATOM   2934  C  CD  . PRO A 1 388 ? 199.997 214.249 217.330 1.00 59.11  ? 388 PRO A CD  1 
ATOM   2935  N  N   . MET A 1 389 ? 203.442 213.053 217.377 1.00 62.17  ? 389 MET A N   1 
ATOM   2936  C  CA  . MET A 1 389 ? 204.609 212.359 217.915 1.00 62.17  ? 389 MET A CA  1 
ATOM   2937  C  C   . MET A 1 389 ? 205.760 212.350 216.920 1.00 62.17  ? 389 MET A C   1 
ATOM   2938  O  O   . MET A 1 389 ? 206.926 212.363 217.324 1.00 62.17  ? 389 MET A O   1 
ATOM   2939  C  CB  . MET A 1 389 ? 204.267 210.918 218.310 1.00 62.17  ? 389 MET A CB  1 
ATOM   2940  C  CG  . MET A 1 389 ? 205.393 210.208 219.091 1.00 62.17  ? 389 MET A CG  1 
ATOM   2941  S  SD  . MET A 1 389 ? 206.815 209.514 218.213 1.00 62.17  ? 389 MET A SD  1 
ATOM   2942  C  CE  . MET A 1 389 ? 206.138 208.050 217.463 1.00 62.17  ? 389 MET A CE  1 
ATOM   2943  N  N   . THR A 1 390 ? 205.458 212.302 215.623 1.00 59.29  ? 390 THR A N   1 
ATOM   2944  C  CA  . THR A 1 390 ? 206.502 212.217 214.612 1.00 59.29  ? 390 THR A CA  1 
ATOM   2945  C  C   . THR A 1 390 ? 206.234 213.101 213.402 1.00 59.29  ? 390 THR A C   1 
ATOM   2946  O  O   . THR A 1 390 ? 206.993 213.034 212.429 1.00 59.29  ? 390 THR A O   1 
ATOM   2947  C  CB  . THR A 1 390 ? 206.685 210.769 214.151 1.00 59.29  ? 390 THR A CB  1 
ATOM   2948  O  OG1 . THR A 1 390 ? 207.748 210.703 213.193 1.00 59.29  ? 390 THR A OG1 1 
ATOM   2949  C  CG2 . THR A 1 390 ? 205.404 210.246 213.524 1.00 59.29  ? 390 THR A CG2 1 
ATOM   2950  N  N   . GLY A 1 391 ? 205.186 213.919 213.423 1.00 55.04  ? 391 GLY A N   1 
ATOM   2951  C  CA  . GLY A 1 391 ? 204.871 214.784 212.310 1.00 55.04  ? 391 GLY A CA  1 
ATOM   2952  C  C   . GLY A 1 391 ? 204.118 214.119 211.188 1.00 55.04  ? 391 GLY A C   1 
ATOM   2953  O  O   . GLY A 1 391 ? 203.766 214.793 210.214 1.00 55.04  ? 391 GLY A O   1 
ATOM   2954  N  N   . LEU A 1 392 ? 203.863 212.827 211.285 1.00 52.38  ? 392 LEU A N   1 
ATOM   2955  C  CA  . LEU A 1 392 ? 203.165 212.098 210.245 1.00 52.38  ? 392 LEU A CA  1 
ATOM   2956  C  C   . LEU A 1 392 ? 201.662 212.255 210.419 1.00 52.38  ? 392 LEU A C   1 
ATOM   2957  O  O   . LEU A 1 392 ? 201.184 212.665 211.476 1.00 52.38  ? 392 LEU A O   1 
ATOM   2958  C  CB  . LEU A 1 392 ? 203.574 210.629 210.283 1.00 52.38  ? 392 LEU A CB  1 
ATOM   2959  C  CG  . LEU A 1 392 ? 204.809 210.217 209.477 1.00 52.38  ? 392 LEU A CG  1 
ATOM   2960  C  CD1 . LEU A 1 392 ? 204.614 210.530 208.005 1.00 52.38  ? 392 LEU A CD1 1 
ATOM   2961  C  CD2 . LEU A 1 392 ? 206.074 210.877 210.004 1.00 52.38  ? 392 LEU A CD2 1 
ATOM   2962  N  N   . PRO A 1 393 ? 200.883 211.959 209.383 1.00 48.01  ? 393 PRO A N   1 
ATOM   2963  C  CA  . PRO A 1 393 ? 199.426 211.993 209.524 1.00 48.01  ? 393 PRO A CA  1 
ATOM   2964  C  C   . PRO A 1 393 ? 198.930 210.950 210.512 1.00 48.01  ? 393 PRO A C   1 
ATOM   2965  O  O   . PRO A 1 393 ? 199.609 209.975 210.838 1.00 48.01  ? 393 PRO A O   1 
ATOM   2966  C  CB  . PRO A 1 393 ? 198.934 211.704 208.108 1.00 48.01  ? 393 PRO A CB  1 
ATOM   2967  C  CG  . PRO A 1 393 ? 200.011 212.194 207.243 1.00 48.01  ? 393 PRO A CG  1 
ATOM   2968  C  CD  . PRO A 1 393 ? 201.289 211.918 207.973 1.00 48.01  ? 393 PRO A CD  1 
ATOM   2969  N  N   . ASN A 1 394 ? 197.714 211.174 210.999 1.00 52.13  ? 394 ASN A N   1 
ATOM   2970  C  CA  . ASN A 1 394 ? 197.105 210.342 212.023 1.00 52.13  ? 394 ASN A CA  1 
ATOM   2971  C  C   . ASN A 1 394 ? 195.986 209.493 211.431 1.00 52.13  ? 394 ASN A C   1 
ATOM   2972  O  O   . ASN A 1 394 ? 195.687 209.545 210.235 1.00 52.13  ? 394 ASN A O   1 
ATOM   2973  C  CB  . ASN A 1 394 ? 196.574 211.195 213.176 1.00 52.13  ? 394 ASN A CB  1 
ATOM   2974  C  CG  . ASN A 1 394 ? 196.507 210.436 214.477 1.00 52.13  ? 394 ASN A CG  1 
ATOM   2975  O  OD1 . ASN A 1 394 ? 197.199 209.437 214.661 1.00 52.13  ? 394 ASN A OD1 1 
ATOM   2976  N  ND2 . ASN A 1 394 ? 195.671 210.906 215.394 1.00 52.13  ? 394 ASN A ND2 1 
ATOM   2977  N  N   . ARG A 1 395 ? 195.368 208.696 212.302 1.00 57.16  ? 395 ARG A N   1 
ATOM   2978  C  CA  . ARG A 1 395 ? 194.366 207.739 211.850 1.00 57.16  ? 395 ARG A CA  1 
ATOM   2979  C  C   . ARG A 1 395 ? 193.178 208.444 211.218 1.00 57.16  ? 395 ARG A C   1 
ATOM   2980  O  O   . ARG A 1 395 ? 192.580 207.934 210.266 1.00 57.16  ? 395 ARG A O   1 
ATOM   2981  C  CB  . ARG A 1 395 ? 193.911 206.862 213.016 1.00 57.16  ? 395 ARG A CB  1 
ATOM   2982  C  CG  . ARG A 1 395 ? 193.122 205.642 212.592 1.00 57.16  ? 395 ARG A CG  1 
ATOM   2983  C  CD  . ARG A 1 395 ? 193.051 204.632 213.708 1.00 57.16  ? 395 ARG A CD  1 
ATOM   2984  N  NE  . ARG A 1 395 ? 192.332 203.431 213.302 1.00 57.16  ? 395 ARG A NE  1 
ATOM   2985  C  CZ  . ARG A 1 395 ? 192.405 202.266 213.930 1.00 57.16  ? 395 ARG A CZ  1 
ATOM   2986  N  NH1 . ARG A 1 395 ? 193.158 202.106 215.006 1.00 57.16  ? 395 ARG A NH1 1 
ATOM   2987  N  NH2 . ARG A 1 395 ? 191.705 201.234 213.466 1.00 57.16  ? 395 ARG A NH2 1 
ATOM   2988  N  N   . ASN A 1 396 ? 192.812 209.613 211.742 1.00 56.05  ? 396 ASN A N   1 
ATOM   2989  C  CA  . ASN A 1 396 ? 191.773 210.403 211.096 1.00 56.05  ? 396 ASN A CA  1 
ATOM   2990  C  C   . ASN A 1 396 ? 192.188 210.770 209.682 1.00 56.05  ? 396 ASN A C   1 
ATOM   2991  O  O   . ASN A 1 396 ? 191.371 210.740 208.754 1.00 56.05  ? 396 ASN A O   1 
ATOM   2992  C  CB  . ASN A 1 396 ? 191.490 211.656 211.917 1.00 56.05  ? 396 ASN A CB  1 
ATOM   2993  C  CG  . ASN A 1 396 ? 191.179 211.342 213.356 1.00 56.05  ? 396 ASN A CG  1 
ATOM   2994  O  OD1 . ASN A 1 396 ? 190.407 210.432 213.649 1.00 56.05  ? 396 ASN A OD1 1 
ATOM   2995  N  ND2 . ASN A 1 396 ? 191.791 212.085 214.269 1.00 56.05  ? 396 ASN A ND2 1 
ATOM   2996  N  N   . ASN A 1 397 ? 193.461 211.112 209.500 1.00 53.21  ? 397 ASN A N   1 
ATOM   2997  C  CA  . ASN A 1 397 ? 193.945 211.451 208.173 1.00 53.21  ? 397 ASN A CA  1 
ATOM   2998  C  C   . ASN A 1 397 ? 193.887 210.250 207.245 1.00 53.21  ? 397 ASN A C   1 
ATOM   2999  O  O   . ASN A 1 397 ? 193.546 210.400 206.070 1.00 53.21  ? 397 ASN A O   1 
ATOM   3000  C  CB  . ASN A 1 397 ? 195.362 212.007 208.261 1.00 53.21  ? 397 ASN A CB  1 
ATOM   3001  C  CG  . ASN A 1 397 ? 195.618 213.100 207.255 1.00 53.21  ? 397 ASN A CG  1 
ATOM   3002  O  OD1 . ASN A 1 397 ? 194.867 213.263 206.297 1.00 53.21  ? 397 ASN A OD1 1 
ATOM   3003  N  ND2 . ASN A 1 397 ? 196.673 213.868 207.474 1.00 53.21  ? 397 ASN A ND2 1 
ATOM   3004  N  N   . LEU A 1 398 ? 194.213 209.056 207.746 1.00 57.10  ? 398 LEU A N   1 
ATOM   3005  C  CA  . LEU A 1 398 ? 194.090 207.859 206.916 1.00 57.10  ? 398 LEU A CA  1 
ATOM   3006  C  C   . LEU A 1 398 ? 192.634 207.569 206.571 1.00 57.10  ? 398 LEU A C   1 
ATOM   3007  O  O   . LEU A 1 398 ? 192.329 207.152 205.448 1.00 57.10  ? 398 LEU A O   1 
ATOM   3008  C  CB  . LEU A 1 398 ? 194.725 206.655 207.611 1.00 57.10  ? 398 LEU A CB  1 
ATOM   3009  C  CG  . LEU A 1 398 ? 194.454 205.274 207.001 1.00 57.10  ? 398 LEU A CG  1 
ATOM   3010  C  CD1 . LEU A 1 398 ? 194.823 205.206 205.528 1.00 57.10  ? 398 LEU A CD1 1 
ATOM   3011  C  CD2 . LEU A 1 398 ? 195.190 204.200 207.785 1.00 57.10  ? 398 LEU A CD2 1 
ATOM   3012  N  N   . HIS A 1 399 ? 191.726 207.755 207.531 1.00 56.46  ? 399 HIS A N   1 
ATOM   3013  C  CA  . HIS A 1 399 ? 190.305 207.608 207.243 1.00 56.46  ? 399 HIS A CA  1 
ATOM   3014  C  C   . HIS A 1 399 ? 189.897 208.540 206.111 1.00 56.46  ? 399 HIS A C   1 
ATOM   3015  O  O   . HIS A 1 399 ? 189.211 208.132 205.165 1.00 56.46  ? 399 HIS A O   1 
ATOM   3016  C  CB  . HIS A 1 399 ? 189.478 207.906 208.496 1.00 56.46  ? 399 HIS A CB  1 
ATOM   3017  C  CG  . HIS A 1 399 ? 189.373 206.760 209.458 1.00 56.46  ? 399 HIS A CG  1 
ATOM   3018  N  ND1 . HIS A 1 399 ? 188.464 205.739 209.303 1.00 56.46  ? 399 HIS A ND1 1 
ATOM   3019  C  CD2 . HIS A 1 399 ? 190.039 206.497 210.607 1.00 56.46  ? 399 HIS A CD2 1 
ATOM   3020  C  CE1 . HIS A 1 399 ? 188.584 204.888 210.306 1.00 56.46  ? 399 HIS A CE1 1 
ATOM   3021  N  NE2 . HIS A 1 399 ? 189.534 205.324 211.110 1.00 56.46  ? 399 HIS A NE2 1 
ATOM   3022  N  N   . ASN A 1 400 ? 190.346 209.794 206.181 1.00 59.80  ? 400 ASN A N   1 
ATOM   3023  C  CA  . ASN A 1 400 ? 190.043 210.768 205.138 1.00 59.80  ? 400 ASN A CA  1 
ATOM   3024  C  C   . ASN A 1 400 ? 190.640 210.351 203.799 1.00 59.80  ? 400 ASN A C   1 
ATOM   3025  O  O   . ASN A 1 400 ? 189.991 210.467 202.755 1.00 59.80  ? 400 ASN A O   1 
ATOM   3026  C  CB  . ASN A 1 400 ? 190.564 212.143 205.553 1.00 59.80  ? 400 ASN A CB  1 
ATOM   3027  C  CG  . ASN A 1 400 ? 189.751 213.270 204.971 1.00 59.80  ? 400 ASN A CG  1 
ATOM   3028  O  OD1 . ASN A 1 400 ? 188.530 213.310 205.118 1.00 59.80  ? 400 ASN A OD1 1 
ATOM   3029  N  ND2 . ASN A 1 400 ? 190.422 214.198 204.304 1.00 59.80  ? 400 ASN A ND2 1 
ATOM   3030  N  N   . TYR A 1 401 ? 191.885 209.877 203.814 1.00 56.15  ? 401 TYR A N   1 
ATOM   3031  C  CA  . TYR A 1 401 ? 192.565 209.483 202.584 1.00 56.15  ? 401 TYR A CA  1 
ATOM   3032  C  C   . TYR A 1 401 ? 191.842 208.327 201.910 1.00 56.15  ? 401 TYR A C   1 
ATOM   3033  O  O   . TYR A 1 401 ? 191.621 208.333 200.693 1.00 56.15  ? 401 TYR A O   1 
ATOM   3034  C  CB  . TYR A 1 401 ? 194.009 209.104 202.914 1.00 56.15  ? 401 TYR A CB  1 
ATOM   3035  C  CG  . TYR A 1 401 ? 194.976 209.146 201.762 1.00 56.15  ? 401 TYR A CG  1 
ATOM   3036  C  CD1 . TYR A 1 401 ? 195.089 208.081 200.889 1.00 56.15  ? 401 TYR A CD1 1 
ATOM   3037  C  CD2 . TYR A 1 401 ? 195.785 210.245 201.557 1.00 56.15  ? 401 TYR A CD2 1 
ATOM   3038  C  CE1 . TYR A 1 401 ? 195.974 208.111 199.840 1.00 56.15  ? 401 TYR A CE1 1 
ATOM   3039  C  CE2 . TYR A 1 401 ? 196.676 210.284 200.512 1.00 56.15  ? 401 TYR A CE2 1 
ATOM   3040  C  CZ  . TYR A 1 401 ? 196.766 209.214 199.655 1.00 56.15  ? 401 TYR A CZ  1 
ATOM   3041  O  OH  . TYR A 1 401 ? 197.655 209.250 198.606 1.00 56.15  ? 401 TYR A OH  1 
ATOM   3042  N  N   . LEU A 1 402 ? 191.469 207.320 202.694 1.00 61.04  ? 402 LEU A N   1 
ATOM   3043  C  CA  . LEU A 1 402 ? 190.767 206.177 202.134 1.00 61.04  ? 402 LEU A CA  1 
ATOM   3044  C  C   . LEU A 1 402 ? 189.394 206.581 201.626 1.00 61.04  ? 402 LEU A C   1 
ATOM   3045  O  O   . LEU A 1 402 ? 188.942 206.086 200.587 1.00 61.04  ? 402 LEU A O   1 
ATOM   3046  C  CB  . LEU A 1 402 ? 190.660 205.063 203.173 1.00 61.04  ? 402 LEU A CB  1 
ATOM   3047  C  CG  . LEU A 1 402 ? 191.918 204.205 203.303 1.00 61.04  ? 402 LEU A CG  1 
ATOM   3048  C  CD1 . LEU A 1 402 ? 191.804 203.243 204.475 1.00 61.04  ? 402 LEU A CD1 1 
ATOM   3049  C  CD2 . LEU A 1 402 ? 192.178 203.457 202.009 1.00 61.04  ? 402 LEU A CD2 1 
ATOM   3050  N  N   . ASP A 1 403 ? 188.710 207.475 202.344 1.00 64.23  ? 403 ASP A N   1 
ATOM   3051  C  CA  . ASP A 1 403 ? 187.438 207.974 201.840 1.00 64.23  ? 403 ASP A CA  1 
ATOM   3052  C  C   . ASP A 1 403 ? 187.627 208.678 200.508 1.00 64.23  ? 403 ASP A C   1 
ATOM   3053  O  O   . ASP A 1 403 ? 186.839 208.484 199.575 1.00 64.23  ? 403 ASP A O   1 
ATOM   3054  C  CB  . ASP A 1 403 ? 186.795 208.917 202.856 1.00 64.23  ? 403 ASP A CB  1 
ATOM   3055  C  CG  . ASP A 1 403 ? 186.103 208.178 203.980 1.00 64.23  ? 403 ASP A CG  1 
ATOM   3056  O  OD1 . ASP A 1 403 ? 185.609 207.056 203.739 1.00 64.23  ? 403 ASP A OD1 1 
ATOM   3057  O  OD2 . ASP A 1 403 ? 186.048 208.721 205.103 1.00 64.23  ? 403 ASP A OD2 1 
ATOM   3058  N  N   . ASP A 1 404 ? 188.678 209.489 200.395 1.00 66.49  ? 404 ASP A N   1 
ATOM   3059  C  CA  . ASP A 1 404 ? 188.932 210.196 199.149 1.00 66.49  ? 404 ASP A CA  1 
ATOM   3060  C  C   . ASP A 1 404 ? 189.185 209.227 198.007 1.00 66.49  ? 404 ASP A C   1 
ATOM   3061  O  O   . ASP A 1 404 ? 188.688 209.434 196.894 1.00 66.49  ? 404 ASP A O   1 
ATOM   3062  C  CB  . ASP A 1 404 ? 190.117 211.146 199.315 1.00 66.49  ? 404 ASP A CB  1 
ATOM   3063  C  CG  . ASP A 1 404 ? 189.719 212.473 199.933 1.00 66.49  ? 404 ASP A CG  1 
ATOM   3064  O  OD1 . ASP A 1 404 ? 188.507 212.774 199.971 1.00 66.49  ? 404 ASP A OD1 1 
ATOM   3065  O  OD2 . ASP A 1 404 ? 190.619 213.216 200.378 1.00 66.49  ? 404 ASP A OD2 1 
ATOM   3066  N  N   . LEU A 1 405 ? 189.950 208.165 198.260 1.00 61.69  ? 405 LEU A N   1 
ATOM   3067  C  CA  . LEU A 1 405 ? 190.237 207.207 197.197 1.00 61.69  ? 405 LEU A CA  1 
ATOM   3068  C  C   . LEU A 1 405 ? 188.994 206.421 196.800 1.00 61.69  ? 405 LEU A C   1 
ATOM   3069  O  O   . LEU A 1 405 ? 188.738 206.212 195.609 1.00 61.69  ? 405 LEU A O   1 
ATOM   3070  C  CB  . LEU A 1 405 ? 191.358 206.263 197.625 1.00 61.69  ? 405 LEU A CB  1 
ATOM   3071  C  CG  . LEU A 1 405 ? 192.676 206.942 197.994 1.00 61.69  ? 405 LEU A CG  1 
ATOM   3072  C  CD1 . LEU A 1 405 ? 193.702 205.906 198.405 1.00 61.69  ? 405 LEU A CD1 1 
ATOM   3073  C  CD2 . LEU A 1 405 ? 193.184 207.777 196.838 1.00 61.69  ? 405 LEU A CD2 1 
ATOM   3074  N  N   . VAL A 1 406 ? 188.205 205.972 197.776 1.00 64.90  ? 406 VAL A N   1 
ATOM   3075  C  CA  . VAL A 1 406 ? 187.028 205.180 197.438 1.00 64.90  ? 406 VAL A CA  1 
ATOM   3076  C  C   . VAL A 1 406 ? 185.990 206.047 196.740 1.00 64.90  ? 406 VAL A C   1 
ATOM   3077  O  O   . VAL A 1 406 ? 185.191 205.554 195.935 1.00 64.90  ? 406 VAL A O   1 
ATOM   3078  C  CB  . VAL A 1 406 ? 186.452 204.485 198.685 1.00 64.90  ? 406 VAL A CB  1 
ATOM   3079  C  CG1 . VAL A 1 406 ? 187.491 203.568 199.311 1.00 64.90  ? 406 VAL A CG1 1 
ATOM   3080  C  CG2 . VAL A 1 406 ? 185.940 205.495 199.687 1.00 64.90  ? 406 VAL A CG2 1 
ATOM   3081  N  N   . ASP A 1 407 ? 185.980 207.350 197.033 1.00 70.01  ? 407 ASP A N   1 
ATOM   3082  C  CA  . ASP A 1 407 ? 185.103 208.250 196.294 1.00 70.01  ? 407 ASP A CA  1 
ATOM   3083  C  C   . ASP A 1 407 ? 185.511 208.358 194.833 1.00 70.01  ? 407 ASP A C   1 
ATOM   3084  O  O   . ASP A 1 407 ? 184.644 208.514 193.967 1.00 70.01  ? 407 ASP A O   1 
ATOM   3085  C  CB  . ASP A 1 407 ? 185.092 209.635 196.943 1.00 70.01  ? 407 ASP A CB  1 
ATOM   3086  C  CG  . ASP A 1 407 ? 184.359 209.650 198.270 1.00 70.01  ? 407 ASP A CG  1 
ATOM   3087  O  OD1 . ASP A 1 407 ? 183.683 208.649 198.588 1.00 70.01  ? 407 ASP A OD1 1 
ATOM   3088  O  OD2 . ASP A 1 407 ? 184.458 210.662 198.994 1.00 70.01  ? 407 ASP A OD2 1 
ATOM   3089  N  N   . LYS A 1 408 ? 186.805 208.276 194.544 1.00 70.30  ? 408 LYS A N   1 
ATOM   3090  C  CA  . LYS A 1 408 ? 187.302 208.238 193.177 1.00 70.30  ? 408 LYS A CA  1 
ATOM   3091  C  C   . LYS A 1 408 ? 187.288 206.831 192.597 1.00 70.30  ? 408 LYS A C   1 
ATOM   3092  O  O   . LYS A 1 408 ? 187.654 206.651 191.431 1.00 70.30  ? 408 LYS A O   1 
ATOM   3093  C  CB  . LYS A 1 408 ? 188.721 208.815 193.118 1.00 70.30  ? 408 LYS A CB  1 
ATOM   3094  C  CG  . LYS A 1 408 ? 189.090 209.450 191.787 1.00 70.30  ? 408 LYS A CG  1 
ATOM   3095  C  CD  . LYS A 1 408 ? 190.128 210.546 191.970 1.00 70.30  ? 408 LYS A CD  1 
ATOM   3096  C  CE  . LYS A 1 408 ? 191.357 210.028 192.700 1.00 70.30  ? 408 LYS A CE  1 
ATOM   3097  N  NZ  . LYS A 1 408 ? 192.330 211.118 192.991 1.00 70.30  ? 408 LYS A NZ  1 
ATOM   3098  N  N   . ALA A 1 409 ? 186.892 205.837 193.396 1.00 69.90  ? 409 ALA A N   1 
ATOM   3099  C  CA  . ALA A 1 409 ? 186.765 204.447 192.955 1.00 69.90  ? 409 ALA A CA  1 
ATOM   3100  C  C   . ALA A 1 409 ? 188.116 203.863 192.548 1.00 69.90  ? 409 ALA A C   1 
ATOM   3101  O  O   . ALA A 1 409 ? 188.239 203.210 191.512 1.00 69.90  ? 409 ALA A O   1 
ATOM   3102  C  CB  . ALA A 1 409 ? 185.748 204.305 191.820 1.00 69.90  ? 409 ALA A CB  1 
ATOM   3103  N  N   . VAL A 1 410 ? 189.136 204.101 193.368 1.00 65.33  ? 410 VAL A N   1 
ATOM   3104  C  CA  . VAL A 1 410 ? 190.459 203.523 193.179 1.00 65.33  ? 410 VAL A CA  1 
ATOM   3105  C  C   . VAL A 1 410 ? 190.833 202.782 194.453 1.00 65.33  ? 410 VAL A C   1 
ATOM   3106  O  O   . VAL A 1 410 ? 190.919 203.391 195.525 1.00 65.33  ? 410 VAL A O   1 
ATOM   3107  C  CB  . VAL A 1 410 ? 191.508 204.596 192.841 1.00 65.33  ? 410 VAL A CB  1 
ATOM   3108  C  CG1 . VAL A 1 410 ? 192.878 203.959 192.674 1.00 65.33  ? 410 VAL A CG1 1 
ATOM   3109  C  CG2 . VAL A 1 410 ? 191.107 205.354 191.585 1.00 65.33  ? 410 VAL A CG2 1 
ATOM   3110  N  N   . SER A 1 411 ? 191.060 201.474 194.335 1.00 57.63  ? 411 SER A N   1 
ATOM   3111  C  CA  . SER A 1 411 ? 191.343 200.640 195.494 1.00 57.63  ? 411 SER A CA  1 
ATOM   3112  C  C   . SER A 1 411 ? 192.835 200.621 195.760 1.00 57.63  ? 411 SER A C   1 
ATOM   3113  O  O   . SER A 1 411 ? 193.607 200.214 194.880 1.00 57.63  ? 411 SER A O   1 
ATOM   3114  C  CB  . SER A 1 411 ? 190.831 199.223 195.276 1.00 57.63  ? 411 SER A CB  1 
ATOM   3115  O  OG  . SER A 1 411 ? 191.055 198.430 196.428 1.00 57.63  ? 411 SER A OG  1 
ATOM   3116  N  N   . PRO A 1 412 ? 193.280 201.041 196.918 1.00 51.70  ? 412 PRO A N   1 
ATOM   3117  C  CA  . PRO A 1 412 ? 194.718 201.100 197.178 1.00 51.70  ? 412 PRO A CA  1 
ATOM   3118  C  C   . PRO A 1 412 ? 195.261 199.856 197.859 1.00 51.70  ? 412 PRO A C   1 
ATOM   3119  O  O   . PRO A 1 412 ? 194.523 198.906 198.133 1.00 51.70  ? 412 PRO A O   1 
ATOM   3120  C  CB  . PRO A 1 412 ? 194.836 202.318 198.091 1.00 51.70  ? 412 PRO A CB  1 
ATOM   3121  C  CG  . PRO A 1 412 ? 193.566 202.264 198.897 1.00 51.70  ? 412 PRO A CG  1 
ATOM   3122  C  CD  . PRO A 1 412 ? 192.504 201.615 198.027 1.00 51.70  ? 412 PRO A CD  1 
ATOM   3123  N  N   . VAL A 1 413 ? 196.564 199.866 198.125 1.00 45.90  ? 413 VAL A N   1 
ATOM   3124  C  CA  . VAL A 1 413 ? 197.226 198.901 198.990 1.00 45.90  ? 413 VAL A CA  1 
ATOM   3125  C  C   . VAL A 1 413 ? 197.518 199.575 200.318 1.00 45.90  ? 413 VAL A C   1 
ATOM   3126  O  O   . VAL A 1 413 ? 197.966 200.728 200.355 1.00 45.90  ? 413 VAL A O   1 
ATOM   3127  C  CB  . VAL A 1 413 ? 198.520 198.350 198.364 1.00 45.90  ? 413 VAL A CB  1 
ATOM   3128  C  CG1 . VAL A 1 413 ? 199.479 199.453 198.045 1.00 45.90  ? 413 VAL A CG1 1 
ATOM   3129  C  CG2 . VAL A 1 413 ? 199.191 197.399 199.327 1.00 45.90  ? 413 VAL A CG2 1 
ATOM   3130  N  N   . VAL A 1 414 ? 197.264 198.854 201.403 1.00 42.15  ? 414 VAL A N   1 
ATOM   3131  C  CA  . VAL A 1 414 ? 197.433 199.373 202.756 1.00 42.15  ? 414 VAL A CA  1 
ATOM   3132  C  C   . VAL A 1 414 ? 198.401 198.450 203.489 1.00 42.15  ? 414 VAL A C   1 
ATOM   3133  O  O   . VAL A 1 414 ? 198.011 197.504 204.173 1.00 42.15  ? 414 VAL A O   1 
ATOM   3134  C  CB  . VAL A 1 414 ? 196.095 199.508 203.488 1.00 42.15  ? 414 VAL A CB  1 
ATOM   3135  C  CG1 . VAL A 1 414 ? 195.293 200.642 202.884 1.00 42.15  ? 414 VAL A CG1 1 
ATOM   3136  C  CG2 . VAL A 1 414 ? 195.279 198.233 203.351 1.00 42.15  ? 414 VAL A CG2 1 
ATOM   3137  N  N   . TYR A 1 415 ? 199.692 198.734 203.373 1.00 43.98  ? 415 TYR A N   1 
ATOM   3138  C  CA  . TYR A 1 415 ? 200.686 198.012 204.147 1.00 43.98  ? 415 TYR A CA  1 
ATOM   3139  C  C   . TYR A 1 415 ? 200.592 198.469 205.590 1.00 43.98  ? 415 TYR A C   1 
ATOM   3140  O  O   . TYR A 1 415 ? 200.718 199.663 205.874 1.00 43.98  ? 415 TYR A O   1 
ATOM   3141  C  CB  . TYR A 1 415 ? 202.092 198.263 203.609 1.00 43.98  ? 415 TYR A CB  1 
ATOM   3142  C  CG  . TYR A 1 415 ? 202.255 198.072 202.121 1.00 43.98  ? 415 TYR A CG  1 
ATOM   3143  C  CD1 . TYR A 1 415 ? 202.393 196.806 201.578 1.00 43.98  ? 415 TYR A CD1 1 
ATOM   3144  C  CD2 . TYR A 1 415 ? 202.290 199.156 201.264 1.00 43.98  ? 415 TYR A CD2 1 
ATOM   3145  C  CE1 . TYR A 1 415 ? 202.547 196.627 200.224 1.00 43.98  ? 415 TYR A CE1 1 
ATOM   3146  C  CE2 . TYR A 1 415 ? 202.445 198.986 199.909 1.00 43.98  ? 415 TYR A CE2 1 
ATOM   3147  C  CZ  . TYR A 1 415 ? 202.573 197.720 199.394 1.00 43.98  ? 415 TYR A CZ  1 
ATOM   3148  O  OH  . TYR A 1 415 ? 202.727 197.548 198.039 1.00 43.98  ? 415 TYR A OH  1 
ATOM   3149  N  N   . LEU A 1 416 ? 200.381 197.530 206.505 1.00 45.24  ? 416 LEU A N   1 
ATOM   3150  C  CA  . LEU A 1 416 ? 200.269 197.862 207.925 1.00 45.24  ? 416 LEU A CA  1 
ATOM   3151  C  C   . LEU A 1 416 ? 201.600 197.553 208.604 1.00 45.24  ? 416 LEU A C   1 
ATOM   3152  O  O   . LEU A 1 416 ? 201.828 196.454 209.105 1.00 45.24  ? 416 LEU A O   1 
ATOM   3153  C  CB  . LEU A 1 416 ? 199.106 197.117 208.563 1.00 45.24  ? 416 LEU A CB  1 
ATOM   3154  C  CG  . LEU A 1 416 ? 198.869 197.457 210.029 1.00 45.24  ? 416 LEU A CG  1 
ATOM   3155  C  CD1 . LEU A 1 416 ? 198.549 198.915 210.181 1.00 45.24  ? 416 LEU A CD1 1 
ATOM   3156  C  CD2 . LEU A 1 416 ? 197.733 196.650 210.560 1.00 45.24  ? 416 LEU A CD2 1 
ATOM   3157  N  N   . ILE A 1 417 ? 202.479 198.543 208.625 1.00 47.63  ? 417 ILE A N   1 
ATOM   3158  C  CA  . ILE A 1 417 ? 203.817 198.376 209.173 1.00 47.63  ? 417 ILE A CA  1 
ATOM   3159  C  C   . ILE A 1 417 ? 203.729 198.343 210.689 1.00 47.63  ? 417 ILE A C   1 
ATOM   3160  O  O   . ILE A 1 417 ? 203.077 199.191 211.304 1.00 47.63  ? 417 ILE A O   1 
ATOM   3161  C  CB  . ILE A 1 417 ? 204.740 199.511 208.704 1.00 47.63  ? 417 ILE A CB  1 
ATOM   3162  C  CG1 . ILE A 1 417 ? 204.591 199.742 207.198 1.00 47.63  ? 417 ILE A CG1 1 
ATOM   3163  C  CG2 . ILE A 1 417 ? 206.184 199.223 209.083 1.00 47.63  ? 417 ILE A CG2 1 
ATOM   3164  C  CD1 . ILE A 1 417 ? 205.007 198.569 206.348 1.00 47.63  ? 417 ILE A CD1 1 
ATOM   3165  N  N   . GLY A 1 418 ? 204.375 197.358 211.294 1.00 53.40  ? 418 GLY A N   1 
ATOM   3166  C  CA  . GLY A 1 418 ? 204.472 197.290 212.734 1.00 53.40  ? 418 GLY A CA  1 
ATOM   3167  C  C   . GLY A 1 418 ? 205.916 197.195 213.165 1.00 53.40  ? 418 GLY A C   1 
ATOM   3168  O  O   . GLY A 1 418 ? 206.601 196.221 212.829 1.00 53.40  ? 418 GLY A O   1 
ATOM   3169  N  N   . VAL A 1 419 ? 206.392 198.207 213.887 1.00 56.94  ? 419 VAL A N   1 
ATOM   3170  C  CA  . VAL A 1 419 ? 207.777 198.254 214.334 1.00 56.94  ? 419 VAL A CA  1 
ATOM   3171  C  C   . VAL A 1 419 ? 207.880 197.486 215.643 1.00 56.94  ? 419 VAL A C   1 
ATOM   3172  O  O   . VAL A 1 419 ? 207.403 197.951 216.683 1.00 56.94  ? 419 VAL A O   1 
ATOM   3173  C  CB  . VAL A 1 419 ? 208.245 199.704 214.507 1.00 56.94  ? 419 VAL A CB  1 
ATOM   3174  C  CG1 . VAL A 1 419 ? 209.588 199.751 215.196 1.00 56.94  ? 419 VAL A CG1 1 
ATOM   3175  C  CG2 . VAL A 1 419 ? 208.299 200.409 213.166 1.00 56.94  ? 419 VAL A CG2 1 
ATOM   3176  N  N   . ASP A 1 420 ? 208.495 196.305 215.600 1.00 63.52  ? 420 ASP A N   1 
ATOM   3177  C  CA  . ASP A 1 420 ? 208.584 195.462 216.781 1.00 63.52  ? 420 ASP A CA  1 
ATOM   3178  C  C   . ASP A 1 420 ? 210.038 195.286 217.194 1.00 63.52  ? 420 ASP A C   1 
ATOM   3179  O  O   . ASP A 1 420 ? 210.968 195.507 216.408 1.00 63.52  ? 420 ASP A O   1 
ATOM   3180  C  CB  . ASP A 1 420 ? 207.907 194.099 216.559 1.00 63.52  ? 420 ASP A CB  1 
ATOM   3181  C  CG  . ASP A 1 420 ? 208.313 193.442 215.261 1.00 63.52  ? 420 ASP A CG  1 
ATOM   3182  O  OD1 . ASP A 1 420 ? 209.508 193.488 214.914 1.00 63.52  ? 420 ASP A OD1 1 
ATOM   3183  O  OD2 . ASP A 1 420 ? 207.429 192.884 214.581 1.00 63.52  ? 420 ASP A OD2 1 
ATOM   3184  N  N   . HIS A 1 421 ? 210.197 194.855 218.447 1.00 66.52  ? 421 HIS A N   1 
ATOM   3185  C  CA  . HIS A 1 421 ? 211.412 194.860 219.263 1.00 66.52  ? 421 HIS A CA  1 
ATOM   3186  C  C   . HIS A 1 421 ? 211.666 196.263 219.794 1.00 66.52  ? 421 HIS A C   1 
ATOM   3187  O  O   . HIS A 1 421 ? 212.779 196.564 220.241 1.00 66.52  ? 421 HIS A O   1 
ATOM   3188  C  CB  . HIS A 1 421 ? 212.643 194.324 218.526 1.00 66.52  ? 421 HIS A CB  1 
ATOM   3189  C  CG  . HIS A 1 421 ? 212.611 192.843 218.310 1.00 66.52  ? 421 HIS A CG  1 
ATOM   3190  N  ND1 . HIS A 1 421 ? 212.046 192.266 217.193 1.00 66.52  ? 421 HIS A ND1 1 
ATOM   3191  C  CD2 . HIS A 1 421 ? 213.062 191.820 219.073 1.00 66.52  ? 421 HIS A CD2 1 
ATOM   3192  C  CE1 . HIS A 1 421 ? 212.155 190.952 217.275 1.00 66.52  ? 421 HIS A CE1 1 
ATOM   3193  N  NE2 . HIS A 1 421 ? 212.769 190.656 218.406 1.00 66.52  ? 421 HIS A NE2 1 
ATOM   3194  N  N   . ILE A 1 422 ? 210.654 197.132 219.758 1.00 68.66  ? 422 ILE A N   1 
ATOM   3195  C  CA  . ILE A 1 422 ? 210.707 198.388 220.498 1.00 68.66  ? 422 ILE A CA  1 
ATOM   3196  C  C   . ILE A 1 422 ? 210.780 198.119 221.993 1.00 68.66  ? 422 ILE A C   1 
ATOM   3197  O  O   . ILE A 1 422 ? 211.347 198.914 222.750 1.00 68.66  ? 422 ILE A O   1 
ATOM   3198  C  CB  . ILE A 1 422 ? 209.491 199.263 220.131 1.00 68.66  ? 422 ILE A CB  1 
ATOM   3199  C  CG1 . ILE A 1 422 ? 209.631 199.794 218.709 1.00 68.66  ? 422 ILE A CG1 1 
ATOM   3200  C  CG2 . ILE A 1 422 ? 209.327 200.426 221.098 1.00 68.66  ? 422 ILE A CG2 1 
ATOM   3201  C  CD1 . ILE A 1 422 ? 210.682 200.866 218.569 1.00 68.66  ? 422 ILE A CD1 1 
ATOM   3202  N  N   . GLN A 1 423 ? 210.218 196.997 222.447 1.00 74.58  ? 423 GLN A N   1 
ATOM   3203  C  CA  . GLN A 1 423 ? 210.309 196.655 223.862 1.00 74.58  ? 423 GLN A CA  1 
ATOM   3204  C  C   . GLN A 1 423 ? 211.757 196.543 224.316 1.00 74.58  ? 423 GLN A C   1 
ATOM   3205  O  O   . GLN A 1 423 ? 212.061 196.782 225.491 1.00 74.58  ? 423 GLN A O   1 
ATOM   3206  C  CB  . GLN A 1 423 ? 209.564 195.349 224.135 1.00 74.58  ? 423 GLN A CB  1 
ATOM   3207  C  CG  . GLN A 1 423 ? 209.144 195.169 225.581 1.00 74.58  ? 423 GLN A CG  1 
ATOM   3208  C  CD  . GLN A 1 423 ? 207.920 195.984 225.935 1.00 74.58  ? 423 GLN A CD  1 
ATOM   3209  O  OE1 . GLN A 1 423 ? 207.201 196.458 225.056 1.00 74.58  ? 423 GLN A OE1 1 
ATOM   3210  N  NE2 . GLN A 1 423 ? 207.674 196.151 227.228 1.00 74.58  ? 423 GLN A NE2 1 
ATOM   3211  N  N   . ASP A 1 424 ? 212.661 196.189 223.401 1.00 76.94  ? 424 ASP A N   1 
ATOM   3212  C  CA  . ASP A 1 424 ? 214.076 196.119 223.744 1.00 76.94  ? 424 ASP A CA  1 
ATOM   3213  C  C   . ASP A 1 424 ? 214.597 197.482 224.174 1.00 76.94  ? 424 ASP A C   1 
ATOM   3214  O  O   . ASP A 1 424 ? 215.211 197.619 225.238 1.00 76.94  ? 424 ASP A O   1 
ATOM   3215  C  CB  . ASP A 1 424 ? 214.876 195.583 222.557 1.00 76.94  ? 424 ASP A CB  1 
ATOM   3216  C  CG  . ASP A 1 424 ? 216.266 195.121 222.951 1.00 76.94  ? 424 ASP A CG  1 
ATOM   3217  O  OD1 . ASP A 1 424 ? 216.560 195.079 224.164 1.00 76.94  ? 424 ASP A OD1 1 
ATOM   3218  O  OD2 . ASP A 1 424 ? 217.065 194.801 222.046 1.00 76.94  ? 424 ASP A OD2 1 
ATOM   3219  N  N   . VAL A 1 425 ? 214.351 198.513 223.366 1.00 73.00  ? 425 VAL A N   1 
ATOM   3220  C  CA  . VAL A 1 425 ? 214.788 199.846 223.761 1.00 73.00  ? 425 VAL A CA  1 
ATOM   3221  C  C   . VAL A 1 425 ? 214.003 200.309 224.979 1.00 73.00  ? 425 VAL A C   1 
ATOM   3222  O  O   . VAL A 1 425 ? 214.520 201.050 225.823 1.00 73.00  ? 425 VAL A O   1 
ATOM   3223  C  CB  . VAL A 1 425 ? 214.681 200.835 222.584 1.00 73.00  ? 425 VAL A CB  1 
ATOM   3224  C  CG1 . VAL A 1 425 ? 213.242 201.114 222.219 1.00 73.00  ? 425 VAL A CG1 1 
ATOM   3225  C  CG2 . VAL A 1 425 ? 215.413 202.131 222.910 1.00 73.00  ? 425 VAL A CG2 1 
ATOM   3226  N  N   . ILE A 1 426 ? 212.758 199.842 225.113 1.00 72.80  ? 426 ILE A N   1 
ATOM   3227  C  CA  . ILE A 1 426 ? 211.922 200.250 226.240 1.00 72.80  ? 426 ILE A CA  1 
ATOM   3228  C  C   . ILE A 1 426 ? 212.553 199.814 227.555 1.00 72.80  ? 426 ILE A C   1 
ATOM   3229  O  O   . ILE A 1 426 ? 212.731 200.615 228.480 1.00 72.80  ? 426 ILE A O   1 
ATOM   3230  C  CB  . ILE A 1 426 ? 210.501 199.683 226.088 1.00 72.80  ? 426 ILE A CB  1 
ATOM   3231  C  CG1 . ILE A 1 426 ? 209.725 200.479 225.044 1.00 72.80  ? 426 ILE A CG1 1 
ATOM   3232  C  CG2 . ILE A 1 426 ? 209.772 199.716 227.414 1.00 72.80  ? 426 ILE A CG2 1 
ATOM   3233  C  CD1 . ILE A 1 426 ? 209.490 201.908 225.445 1.00 72.80  ? 426 ILE A CD1 1 
ATOM   3234  N  N   . ASP A 1 427 ? 212.920 198.538 227.650 1.00 80.06  ? 427 ASP A N   1 
ATOM   3235  C  CA  . ASP A 1 427 ? 213.466 198.048 228.908 1.00 80.06  ? 427 ASP A CA  1 
ATOM   3236  C  C   . ASP A 1 427 ? 214.980 198.183 228.990 1.00 80.06  ? 427 ASP A C   1 
ATOM   3237  O  O   . ASP A 1 427 ? 215.552 197.861 230.036 1.00 80.06  ? 427 ASP A O   1 
ATOM   3238  C  CB  . ASP A 1 427 ? 213.040 196.593 229.155 1.00 80.06  ? 427 ASP A CB  1 
ATOM   3239  C  CG  . ASP A 1 427 ? 213.551 195.630 228.097 1.00 80.06  ? 427 ASP A CG  1 
ATOM   3240  O  OD1 . ASP A 1 427 ? 214.256 196.059 227.165 1.00 80.06  ? 427 ASP A OD1 1 
ATOM   3241  O  OD2 . ASP A 1 427 ? 213.242 194.424 228.204 1.00 80.06  ? 427 ASP A OD2 1 
ATOM   3242  N  N   . SER A 1 428 ? 215.642 198.652 227.931 1.00 76.08  ? 428 SER A N   1 
ATOM   3243  C  CA  . SER A 1 428 ? 217.076 198.880 228.025 1.00 76.08  ? 428 SER A CA  1 
ATOM   3244  C  C   . SER A 1 428 ? 217.409 200.337 228.334 1.00 76.08  ? 428 SER A C   1 
ATOM   3245  O  O   . SER A 1 428 ? 218.252 200.610 229.194 1.00 76.08  ? 428 SER A O   1 
ATOM   3246  C  CB  . SER A 1 428 ? 217.764 198.434 226.732 1.00 76.08  ? 428 SER A CB  1 
ATOM   3247  O  OG  . SER A 1 428 ? 217.169 199.043 225.604 1.00 76.08  ? 428 SER A OG  1 
ATOM   3248  N  N   . LEU A 1 429 ? 216.778 201.281 227.639 1.00 71.31  ? 429 LEU A N   1 
ATOM   3249  C  CA  . LEU A 1 429 ? 217.015 202.694 227.904 1.00 71.31  ? 429 LEU A CA  1 
ATOM   3250  C  C   . LEU A 1 429 ? 215.784 203.450 228.371 1.00 71.31  ? 429 LEU A C   1 
ATOM   3251  O  O   . LEU A 1 429 ? 215.835 204.101 229.414 1.00 71.31  ? 429 LEU A O   1 
ATOM   3252  C  CB  . LEU A 1 429 ? 217.599 203.377 226.666 1.00 71.31  ? 429 LEU A CB  1 
ATOM   3253  C  CG  . LEU A 1 429 ? 219.127 203.454 226.620 1.00 71.31  ? 429 LEU A CG  1 
ATOM   3254  C  CD1 . LEU A 1 429 ? 219.637 204.291 227.784 1.00 71.31  ? 429 LEU A CD1 1 
ATOM   3255  C  CD2 . LEU A 1 429 ? 219.770 202.077 226.633 1.00 71.31  ? 429 LEU A CD2 1 
ATOM   3256  N  N   . GLY A 1 430 ? 214.678 203.393 227.639 1.00 72.43  ? 430 GLY A N   1 
ATOM   3257  C  CA  . GLY A 1 430 ? 213.485 204.049 228.122 1.00 72.43  ? 430 GLY A CA  1 
ATOM   3258  C  C   . GLY A 1 430 ? 212.642 204.594 226.992 1.00 72.43  ? 430 GLY A C   1 
ATOM   3259  O  O   . GLY A 1 430 ? 212.908 204.348 225.809 1.00 72.43  ? 430 GLY A O   1 
ATOM   3260  N  N   . TYR A 1 431 ? 211.620 205.361 227.373 1.00 73.72  ? 431 TYR A N   1 
ATOM   3261  C  CA  . TYR A 1 431 ? 210.610 205.802 226.419 1.00 73.72  ? 431 TYR A CA  1 
ATOM   3262  C  C   . TYR A 1 431 ? 211.107 206.940 225.535 1.00 73.72  ? 431 TYR A C   1 
ATOM   3263  O  O   . TYR A 1 431 ? 210.741 207.014 224.357 1.00 73.72  ? 431 TYR A O   1 
ATOM   3264  C  CB  . TYR A 1 431 ? 209.344 206.213 227.167 1.00 73.72  ? 431 TYR A CB  1 
ATOM   3265  C  CG  . TYR A 1 431 ? 208.733 205.076 227.950 1.00 73.72  ? 431 TYR A CG  1 
ATOM   3266  C  CD1 . TYR A 1 431 ? 207.819 204.215 227.360 1.00 73.72  ? 431 TYR A CD1 1 
ATOM   3267  C  CD2 . TYR A 1 431 ? 209.083 204.854 229.274 1.00 73.72  ? 431 TYR A CD2 1 
ATOM   3268  C  CE1 . TYR A 1 431 ? 207.266 203.171 228.067 1.00 73.72  ? 431 TYR A CE1 1 
ATOM   3269  C  CE2 . TYR A 1 431 ? 208.535 203.812 229.990 1.00 73.72  ? 431 TYR A CE2 1 
ATOM   3270  C  CZ  . TYR A 1 431 ? 207.625 202.974 229.383 1.00 73.72  ? 431 TYR A CZ  1 
ATOM   3271  O  OH  . TYR A 1 431 ? 207.076 201.933 230.095 1.00 73.72  ? 431 TYR A OH  1 
ATOM   3272  N  N   . ALA A 1 432 ? 211.932 207.839 226.075 1.00 75.61  ? 432 ALA A N   1 
ATOM   3273  C  CA  . ALA A 1 432 ? 212.500 208.895 225.243 1.00 75.61  ? 432 ALA A CA  1 
ATOM   3274  C  C   . ALA A 1 432 ? 213.388 208.312 224.151 1.00 75.61  ? 432 ALA A C   1 
ATOM   3275  O  O   . ALA A 1 432 ? 213.318 208.727 222.989 1.00 75.61  ? 432 ALA A O   1 
ATOM   3276  C  CB  . ALA A 1 432 ? 213.284 209.883 226.106 1.00 75.61  ? 432 ALA A CB  1 
ATOM   3277  N  N   . TRP A 1 433 ? 214.221 207.334 224.503 1.00 74.52  ? 433 TRP A N   1 
ATOM   3278  C  CA  . TRP A 1 433 ? 215.049 206.689 223.498 1.00 74.52  ? 433 TRP A CA  1 
ATOM   3279  C  C   . TRP A 1 433 ? 214.220 205.821 222.565 1.00 74.52  ? 433 TRP A C   1 
ATOM   3280  O  O   . TRP A 1 433 ? 214.591 205.641 221.402 1.00 74.52  ? 433 TRP A O   1 
ATOM   3281  C  CB  . TRP A 1 433 ? 216.144 205.866 224.165 1.00 74.52  ? 433 TRP A CB  1 
ATOM   3282  C  CG  . TRP A 1 433 ? 217.060 206.685 225.021 1.00 74.52  ? 433 TRP A CG  1 
ATOM   3283  C  CD1 . TRP A 1 433 ? 217.151 206.663 226.382 1.00 74.52  ? 433 TRP A CD1 1 
ATOM   3284  C  CD2 . TRP A 1 433 ? 218.011 207.659 224.573 1.00 74.52  ? 433 TRP A CD2 1 
ATOM   3285  N  NE1 . TRP A 1 433 ? 218.106 207.553 226.808 1.00 74.52  ? 433 TRP A NE1 1 
ATOM   3286  C  CE2 . TRP A 1 433 ? 218.646 208.178 225.716 1.00 74.52  ? 433 TRP A CE2 1 
ATOM   3287  C  CE3 . TRP A 1 433 ? 218.388 208.139 223.318 1.00 74.52  ? 433 TRP A CE3 1 
ATOM   3288  C  CZ2 . TRP A 1 433 ? 219.637 209.147 225.639 1.00 74.52  ? 433 TRP A CZ2 1 
ATOM   3289  C  CZ3 . TRP A 1 433 ? 219.370 209.104 223.247 1.00 74.52  ? 433 TRP A CZ3 1 
ATOM   3290  C  CH2 . TRP A 1 433 ? 219.982 209.598 224.399 1.00 74.52  ? 433 TRP A CH2 1 
ATOM   3291  N  N   . ALA A 1 434 ? 213.098 205.278 223.043 1.00 73.25  ? 434 ALA A N   1 
ATOM   3292  C  CA  . ALA A 1 434 ? 212.182 204.592 222.138 1.00 73.25  ? 434 ALA A CA  1 
ATOM   3293  C  C   . ALA A 1 434 ? 211.622 205.553 221.098 1.00 73.25  ? 434 ALA A C   1 
ATOM   3294  O  O   . ALA A 1 434 ? 211.522 205.215 219.912 1.00 73.25  ? 434 ALA A O   1 
ATOM   3295  C  CB  . ALA A 1 434 ? 211.051 203.940 222.927 1.00 73.25  ? 434 ALA A CB  1 
ATOM   3296  N  N   . ASP A 1 435 ? 211.255 206.761 221.528 1.00 78.79  ? 435 ASP A N   1 
ATOM   3297  C  CA  . ASP A 1 435 ? 210.800 207.783 220.591 1.00 78.79  ? 435 ASP A CA  1 
ATOM   3298  C  C   . ASP A 1 435 ? 211.911 208.182 219.627 1.00 78.79  ? 435 ASP A C   1 
ATOM   3299  O  O   . ASP A 1 435 ? 211.658 208.423 218.443 1.00 78.79  ? 435 ASP A O   1 
ATOM   3300  C  CB  . ASP A 1 435 ? 210.284 209.003 221.354 1.00 78.79  ? 435 ASP A CB  1 
ATOM   3301  C  CG  . ASP A 1 435 ? 209.085 208.681 222.223 1.00 78.79  ? 435 ASP A CG  1 
ATOM   3302  O  OD1 . ASP A 1 435 ? 208.404 207.670 221.948 1.00 78.79  ? 435 ASP A OD1 1 
ATOM   3303  O  OD2 . ASP A 1 435 ? 208.823 209.437 223.182 1.00 78.79  ? 435 ASP A OD2 1 
ATOM   3304  N  N   . GLN A 1 436 ? 213.148 208.272 220.122 1.00 71.09  ? 436 GLN A N   1 
ATOM   3305  C  CA  . GLN A 1 436 ? 214.278 208.571 219.244 1.00 71.09  ? 436 GLN A CA  1 
ATOM   3306  C  C   . GLN A 1 436 ? 214.468 207.482 218.197 1.00 71.09  ? 436 GLN A C   1 
ATOM   3307  O  O   . GLN A 1 436 ? 214.742 207.773 217.027 1.00 71.09  ? 436 GLN A O   1 
ATOM   3308  C  CB  . GLN A 1 436 ? 215.549 208.737 220.068 1.00 71.09  ? 436 GLN A CB  1 
ATOM   3309  C  CG  . GLN A 1 436 ? 215.651 210.073 220.744 1.00 71.09  ? 436 GLN A CG  1 
ATOM   3310  C  CD  . GLN A 1 436 ? 215.653 211.205 219.757 1.00 71.09  ? 436 GLN A CD  1 
ATOM   3311  O  OE1 . GLN A 1 436 ? 216.598 211.369 218.990 1.00 71.09  ? 436 GLN A OE1 1 
ATOM   3312  N  NE2 . GLN A 1 436 ? 214.590 211.994 219.760 1.00 71.09  ? 436 GLN A NE2 1 
ATOM   3313  N  N   . ALA A 1 437 ? 214.343 206.220 218.603 1.00 68.28  ? 437 ALA A N   1 
ATOM   3314  C  CA  . ALA A 1 437 ? 214.447 205.121 217.653 1.00 68.28  ? 437 ALA A CA  1 
ATOM   3315  C  C   . ALA A 1 437 ? 213.328 205.181 216.625 1.00 68.28  ? 437 ALA A C   1 
ATOM   3316  O  O   . ALA A 1 437 ? 213.556 204.944 215.432 1.00 68.28  ? 437 ALA A O   1 
ATOM   3317  C  CB  . ALA A 1 437 ? 214.429 203.784 218.390 1.00 68.28  ? 437 ALA A CB  1 
ATOM   3318  N  N   . LEU A 1 438 ? 212.110 205.497 217.068 1.00 67.09  ? 438 LEU A N   1 
ATOM   3319  C  CA  . LEU A 1 438 ? 211.011 205.658 216.122 1.00 67.09  ? 438 LEU A CA  1 
ATOM   3320  C  C   . LEU A 1 438 ? 211.291 206.792 215.145 1.00 67.09  ? 438 LEU A C   1 
ATOM   3321  O  O   . LEU A 1 438 ? 210.999 206.678 213.950 1.00 67.09  ? 438 LEU A O   1 
ATOM   3322  C  CB  . LEU A 1 438 ? 209.702 205.904 216.865 1.00 67.09  ? 438 LEU A CB  1 
ATOM   3323  C  CG  . LEU A 1 438 ? 208.924 204.645 217.228 1.00 67.09  ? 438 LEU A CG  1 
ATOM   3324  C  CD1 . LEU A 1 438 ? 207.931 204.929 218.344 1.00 67.09  ? 438 LEU A CD1 1 
ATOM   3325  C  CD2 . LEU A 1 438 ? 208.223 204.106 215.998 1.00 67.09  ? 438 LEU A CD2 1 
ATOM   3326  N  N   . LEU A 1 439 ? 211.858 207.894 215.638 1.00 67.28  ? 439 LEU A N   1 
ATOM   3327  C  CA  . LEU A 1 439 ? 212.226 209.001 214.762 1.00 67.28  ? 439 LEU A CA  1 
ATOM   3328  C  C   . LEU A 1 439 ? 213.262 208.569 213.733 1.00 67.28  ? 439 LEU A C   1 
ATOM   3329  O  O   . LEU A 1 439 ? 213.182 208.942 212.560 1.00 67.28  ? 439 LEU A O   1 
ATOM   3330  C  CB  . LEU A 1 439 ? 212.748 210.171 215.591 1.00 67.28  ? 439 LEU A CB  1 
ATOM   3331  C  CG  . LEU A 1 439 ? 211.697 210.920 216.394 1.00 67.28  ? 439 LEU A CG  1 
ATOM   3332  C  CD1 . LEU A 1 439 ? 212.357 211.894 217.341 1.00 67.28  ? 439 LEU A CD1 1 
ATOM   3333  C  CD2 . LEU A 1 439 ? 210.768 211.650 215.452 1.00 67.28  ? 439 LEU A CD2 1 
ATOM   3334  N  N   . GLU A 1 440 ? 214.253 207.789 214.157 1.00 66.83  ? 440 GLU A N   1 
ATOM   3335  C  CA  . GLU A 1 440 ? 215.268 207.327 213.217 1.00 66.83  ? 440 GLU A CA  1 
ATOM   3336  C  C   . GLU A 1 440 ? 214.653 206.435 212.147 1.00 66.83  ? 440 GLU A C   1 
ATOM   3337  O  O   . GLU A 1 440 ? 214.960 206.567 210.953 1.00 66.83  ? 440 GLU A O   1 
ATOM   3338  C  CB  . GLU A 1 440 ? 216.371 206.588 213.968 1.00 66.83  ? 440 GLU A CB  1 
ATOM   3339  C  CG  . GLU A 1 440 ? 217.711 206.618 213.277 1.00 66.83  ? 440 GLU A CG  1 
ATOM   3340  C  CD  . GLU A 1 440 ? 218.439 207.918 213.519 1.00 66.83  ? 440 GLU A CD  1 
ATOM   3341  O  OE1 . GLU A 1 440 ? 218.241 208.509 214.600 1.00 66.83  ? 440 GLU A OE1 1 
ATOM   3342  O  OE2 . GLU A 1 440 ? 219.205 208.351 212.632 1.00 66.83  ? 440 GLU A OE2 1 
ATOM   3343  N  N   . VAL A 1 441 ? 213.768 205.528 212.556 1.00 62.85  ? 441 VAL A N   1 
ATOM   3344  C  CA  . VAL A 1 441 ? 213.156 204.624 211.592 1.00 62.85  ? 441 VAL A CA  1 
ATOM   3345  C  C   . VAL A 1 441 ? 212.264 205.399 210.625 1.00 62.85  ? 441 VAL A C   1 
ATOM   3346  O  O   . VAL A 1 441 ? 212.243 205.114 209.421 1.00 62.85  ? 441 VAL A O   1 
ATOM   3347  C  CB  . VAL A 1 441 ? 212.396 203.500 212.320 1.00 62.85  ? 441 VAL A CB  1 
ATOM   3348  C  CG1 . VAL A 1 441 ? 211.833 202.512 211.334 1.00 62.85  ? 441 VAL A CG1 1 
ATOM   3349  C  CG2 . VAL A 1 441 ? 213.323 202.776 213.267 1.00 62.85  ? 441 VAL A CG2 1 
ATOM   3350  N  N   . VAL A 1 442 ? 211.537 206.408 211.117 1.00 62.30  ? 442 VAL A N   1 
ATOM   3351  C  CA  . VAL A 1 442 ? 210.695 207.177 210.204 1.00 62.30  ? 442 VAL A CA  1 
ATOM   3352  C  C   . VAL A 1 442 ? 211.541 208.066 209.303 1.00 62.30  ? 442 VAL A C   1 
ATOM   3353  O  O   . VAL A 1 442 ? 211.144 208.364 208.171 1.00 62.30  ? 442 VAL A O   1 
ATOM   3354  C  CB  . VAL A 1 442 ? 209.628 207.998 210.954 1.00 62.30  ? 442 VAL A CB  1 
ATOM   3355  C  CG1 . VAL A 1 442 ? 208.786 207.099 211.837 1.00 62.30  ? 442 VAL A CG1 1 
ATOM   3356  C  CG2 . VAL A 1 442 ? 210.251 209.126 211.748 1.00 62.30  ? 442 VAL A CG2 1 
ATOM   3357  N  N   . ASN A 1 443 ? 212.712 208.505 209.771 1.00 61.31  ? 443 ASN A N   1 
ATOM   3358  C  CA  . ASN A 1 443 ? 213.614 209.242 208.894 1.00 61.31  ? 443 ASN A CA  1 
ATOM   3359  C  C   . ASN A 1 443 ? 214.105 208.360 207.759 1.00 61.31  ? 443 ASN A C   1 
ATOM   3360  O  O   . ASN A 1 443 ? 214.181 208.802 206.608 1.00 61.31  ? 443 ASN A O   1 
ATOM   3361  C  CB  . ASN A 1 443 ? 214.792 209.795 209.685 1.00 61.31  ? 443 ASN A CB  1 
ATOM   3362  C  CG  . ASN A 1 443 ? 215.270 211.121 209.152 1.00 61.31  ? 443 ASN A CG  1 
ATOM   3363  O  OD1 . ASN A 1 443 ? 214.498 212.072 209.048 1.00 61.31  ? 443 ASN A OD1 1 
ATOM   3364  N  ND2 . ASN A 1 443 ? 216.550 211.197 208.812 1.00 61.31  ? 443 ASN A ND2 1 
ATOM   3365  N  N   . ARG A 1 444 ? 214.432 207.105 208.064 1.00 58.96  ? 444 ARG A N   1 
ATOM   3366  C  CA  . ARG A 1 444 ? 214.768 206.156 207.008 1.00 58.96  ? 444 ARG A CA  1 
ATOM   3367  C  C   . ARG A 1 444 ? 213.598 205.969 206.049 1.00 58.96  ? 444 ARG A C   1 
ATOM   3368  O  O   . ARG A 1 444 ? 213.771 205.965 204.820 1.00 58.96  ? 444 ARG A O   1 
ATOM   3369  C  CB  . ARG A 1 444 ? 215.176 204.820 207.624 1.00 58.96  ? 444 ARG A CB  1 
ATOM   3370  C  CG  . ARG A 1 444 ? 216.624 204.750 208.077 1.00 58.96  ? 444 ARG A CG  1 
ATOM   3371  C  CD  . ARG A 1 444 ? 216.777 203.766 209.226 1.00 58.96  ? 444 ARG A CD  1 
ATOM   3372  N  NE  . ARG A 1 444 ? 218.166 203.444 209.530 1.00 58.96  ? 444 ARG A NE  1 
ATOM   3373  C  CZ  . ARG A 1 444 ? 219.044 204.298 210.036 1.00 58.96  ? 444 ARG A CZ  1 
ATOM   3374  N  NH1 . ARG A 1 444 ? 218.728 205.561 210.269 1.00 58.96  ? 444 ARG A NH1 1 
ATOM   3375  N  NH2 . ARG A 1 444 ? 220.270 203.873 210.321 1.00 58.96  ? 444 ARG A NH2 1 
ATOM   3376  N  N   . PHE A 1 445 ? 212.391 205.826 206.598 1.00 60.26  ? 445 PHE A N   1 
ATOM   3377  C  CA  . PHE A 1 445 ? 211.205 205.645 205.767 1.00 60.26  ? 445 PHE A CA  1 
ATOM   3378  C  C   . PHE A 1 445 ? 211.003 206.819 204.819 1.00 60.26  ? 445 PHE A C   1 
ATOM   3379  O  O   . PHE A 1 445 ? 210.661 206.632 203.648 1.00 60.26  ? 445 PHE A O   1 
ATOM   3380  C  CB  . PHE A 1 445 ? 209.965 205.475 206.642 1.00 60.26  ? 445 PHE A CB  1 
ATOM   3381  C  CG  . PHE A 1 445 ? 209.799 204.101 207.209 1.00 60.26  ? 445 PHE A CG  1 
ATOM   3382  C  CD1 . PHE A 1 445 ? 209.835 202.990 206.389 1.00 60.26  ? 445 PHE A CD1 1 
ATOM   3383  C  CD2 . PHE A 1 445 ? 209.555 203.924 208.556 1.00 60.26  ? 445 PHE A CD2 1 
ATOM   3384  C  CE1 . PHE A 1 445 ? 209.666 201.724 206.911 1.00 60.26  ? 445 PHE A CE1 1 
ATOM   3385  C  CE2 . PHE A 1 445 ? 209.376 202.665 209.079 1.00 60.26  ? 445 PHE A CE2 1 
ATOM   3386  C  CZ  . PHE A 1 445 ? 209.436 201.562 208.257 1.00 60.26  ? 445 PHE A CZ  1 
ATOM   3387  N  N   . ARG A 1 446 ? 211.203 208.041 205.312 1.00 59.69  ? 446 ARG A N   1 
ATOM   3388  C  CA  . ARG A 1 446 ? 210.968 209.213 204.476 1.00 59.69  ? 446 ARG A CA  1 
ATOM   3389  C  C   . ARG A 1 446 ? 212.093 209.414 203.468 1.00 59.69  ? 446 ARG A C   1 
ATOM   3390  O  O   . ARG A 1 446 ? 211.847 209.859 202.341 1.00 59.69  ? 446 ARG A O   1 
ATOM   3391  C  CB  . ARG A 1 446 ? 210.791 210.458 205.341 1.00 59.69  ? 446 ARG A CB  1 
ATOM   3392  C  CG  . ARG A 1 446 ? 209.968 211.539 204.666 1.00 59.69  ? 446 ARG A CG  1 
ATOM   3393  C  CD  . ARG A 1 446 ? 209.766 212.736 205.569 1.00 59.69  ? 446 ARG A CD  1 
ATOM   3394  N  NE  . ARG A 1 446 ? 209.105 212.373 206.815 1.00 59.69  ? 446 ARG A NE  1 
ATOM   3395  C  CZ  . ARG A 1 446 ? 209.656 212.508 208.013 1.00 59.69  ? 446 ARG A CZ  1 
ATOM   3396  N  NH1 . ARG A 1 446 ? 210.875 212.999 208.161 1.00 59.69  ? 446 ARG A NH1 1 
ATOM   3397  N  NH2 . ARG A 1 446 ? 208.967 212.141 209.089 1.00 59.69  ? 446 ARG A NH2 1 
ATOM   3398  N  N   . GLU A 1 447 ? 213.334 209.103 203.849 1.00 60.00  ? 447 GLU A N   1 
ATOM   3399  C  CA  . GLU A 1 447 ? 214.430 209.223 202.896 1.00 60.00  ? 447 GLU A CA  1 
ATOM   3400  C  C   . GLU A 1 447 ? 214.328 208.189 201.787 1.00 60.00  ? 447 GLU A C   1 
ATOM   3401  O  O   . GLU A 1 447 ? 214.860 208.416 200.696 1.00 60.00  ? 447 GLU A O   1 
ATOM   3402  C  CB  . GLU A 1 447 ? 215.778 209.106 203.607 1.00 60.00  ? 447 GLU A CB  1 
ATOM   3403  C  CG  . GLU A 1 447 ? 216.220 207.689 203.900 1.00 60.00  ? 447 GLU A CG  1 
ATOM   3404  C  CD  . GLU A 1 447 ? 217.544 207.635 204.635 1.00 60.00  ? 447 GLU A CD  1 
ATOM   3405  O  OE1 . GLU A 1 447 ? 218.096 208.711 204.945 1.00 60.00  ? 447 GLU A OE1 1 
ATOM   3406  O  OE2 . GLU A 1 447 ? 218.031 206.516 204.902 1.00 60.00  ? 447 GLU A OE2 1 
ATOM   3407  N  N   . LYS A 1 448 ? 213.661 207.062 202.032 1.00 53.93  ? 448 LYS A N   1 
ATOM   3408  C  CA  . LYS A 1 448 ? 213.397 206.112 200.959 1.00 53.93  ? 448 LYS A CA  1 
ATOM   3409  C  C   . LYS A 1 448 ? 211.997 206.229 200.370 1.00 53.93  ? 448 LYS A C   1 
ATOM   3410  O  O   . LYS A 1 448 ? 211.663 205.459 199.466 1.00 53.93  ? 448 LYS A O   1 
ATOM   3411  C  CB  . LYS A 1 448 ? 213.616 204.679 201.446 1.00 53.93  ? 448 LYS A CB  1 
ATOM   3412  C  CG  . LYS A 1 448 ? 215.062 204.331 201.702 1.00 53.93  ? 448 LYS A CG  1 
ATOM   3413  C  CD  . LYS A 1 448 ? 215.865 204.338 200.418 1.00 53.93  ? 448 LYS A CD  1 
ATOM   3414  C  CE  . LYS A 1 448 ? 215.451 203.194 199.509 1.00 53.93  ? 448 LYS A CE  1 
ATOM   3415  N  NZ  . LYS A 1 448 ? 215.762 201.869 200.114 1.00 53.93  ? 448 LYS A NZ  1 
ATOM   3416  N  N   . LEU A 1 449 ? 211.175 207.157 200.849 1.00 51.45  ? 449 LEU A N   1 
ATOM   3417  C  CA  . LEU A 1 449 ? 209.807 207.258 200.360 1.00 51.45  ? 449 LEU A CA  1 
ATOM   3418  C  C   . LEU A 1 449 ? 209.770 207.773 198.927 1.00 51.45  ? 449 LEU A C   1 
ATOM   3419  O  O   . LEU A 1 449 ? 210.628 208.551 198.505 1.00 51.45  ? 449 LEU A O   1 
ATOM   3420  C  CB  . LEU A 1 449 ? 208.986 208.175 201.267 1.00 51.45  ? 449 LEU A CB  1 
ATOM   3421  C  CG  . LEU A 1 449 ? 207.462 208.120 201.113 1.00 51.45  ? 449 LEU A CG  1 
ATOM   3422  C  CD1 . LEU A 1 449 ? 206.879 206.961 201.904 1.00 51.45  ? 449 LEU A CD1 1 
ATOM   3423  C  CD2 . LEU A 1 449 ? 206.822 209.431 201.535 1.00 51.45  ? 449 LEU A CD2 1 
ATOM   3424  N  N   . LYS A 1 450 ? 208.767 207.329 198.183 1.00 50.88  ? 450 LYS A N   1 
ATOM   3425  C  CA  . LYS A 1 450 ? 208.517 207.772 196.820 1.00 50.88  ? 450 LYS A CA  1 
ATOM   3426  C  C   . LYS A 1 450 ? 207.492 208.892 196.815 1.00 50.88  ? 450 LYS A C   1 
ATOM   3427  O  O   . LYS A 1 450 ? 206.790 209.115 197.802 1.00 50.88  ? 450 LYS A O   1 
ATOM   3428  C  CB  . LYS A 1 450 ? 208.045 206.592 195.977 1.00 50.88  ? 450 LYS A CB  1 
ATOM   3429  C  CG  . LYS A 1 450 ? 209.170 205.865 195.259 1.00 50.88  ? 450 LYS A CG  1 
ATOM   3430  C  CD  . LYS A 1 450 ? 208.638 204.947 194.171 1.00 50.88  ? 450 LYS A CD  1 
ATOM   3431  C  CE  . LYS A 1 450 ? 208.191 203.614 194.742 1.00 50.88  ? 450 LYS A CE  1 
ATOM   3432  N  NZ  . LYS A 1 450 ? 209.212 203.039 195.659 1.00 50.88  ? 450 LYS A NZ  1 
ATOM   3433  N  N   . PRO A 1 451 ? 207.394 209.645 195.715 1.00 49.55  ? 451 PRO A N   1 
ATOM   3434  C  CA  . PRO A 1 451 ? 206.454 210.780 195.689 1.00 49.55  ? 451 PRO A CA  1 
ATOM   3435  C  C   . PRO A 1 451 ? 204.997 210.404 195.865 1.00 49.55  ? 451 PRO A C   1 
ATOM   3436  O  O   . PRO A 1 451 ? 204.240 211.187 196.450 1.00 49.55  ? 451 PRO A O   1 
ATOM   3437  C  CB  . PRO A 1 451 ? 206.699 211.404 194.308 1.00 49.55  ? 451 PRO A CB  1 
ATOM   3438  C  CG  . PRO A 1 451 ? 207.358 210.335 193.513 1.00 49.55  ? 451 PRO A CG  1 
ATOM   3439  C  CD  . PRO A 1 451 ? 208.202 209.590 194.488 1.00 49.55  ? 451 PRO A CD  1 
ATOM   3440  N  N   . ASP A 1 452 ? 204.568 209.240 195.382 1.00 51.02  ? 452 ASP A N   1 
ATOM   3441  C  CA  . ASP A 1 452 ? 203.154 208.895 195.349 1.00 51.02  ? 452 ASP A CA  1 
ATOM   3442  C  C   . ASP A 1 452 ? 202.747 207.948 196.474 1.00 51.02  ? 452 ASP A C   1 
ATOM   3443  O  O   . ASP A 1 452 ? 201.690 207.316 196.392 1.00 51.02  ? 452 ASP A O   1 
ATOM   3444  C  CB  . ASP A 1 452 ? 202.795 208.288 193.994 1.00 51.02  ? 452 ASP A CB  1 
ATOM   3445  C  CG  . ASP A 1 452 ? 201.322 208.418 193.669 1.00 51.02  ? 452 ASP A CG  1 
ATOM   3446  O  OD1 . ASP A 1 452 ? 200.876 209.543 193.359 1.00 51.02  ? 452 ASP A OD1 1 
ATOM   3447  O  OD2 . ASP A 1 452 ? 200.608 207.395 193.727 1.00 51.02  ? 452 ASP A OD2 1 
ATOM   3448  N  N   . GLN A 1 453 ? 203.555 207.848 197.523 1.00 52.21  ? 453 GLN A N   1 
ATOM   3449  C  CA  . GLN A 1 453 ? 203.295 206.958 198.644 1.00 52.21  ? 453 GLN A CA  1 
ATOM   3450  C  C   . GLN A 1 453 ? 202.794 207.772 199.827 1.00 52.21  ? 453 GLN A C   1 
ATOM   3451  O  O   . GLN A 1 453 ? 203.422 208.765 200.205 1.00 52.21  ? 453 GLN A O   1 
ATOM   3452  C  CB  . GLN A 1 453 ? 204.562 206.199 199.035 1.00 52.21  ? 453 GLN A CB  1 
ATOM   3453  C  CG  . GLN A 1 453 ? 205.027 205.186 198.020 1.00 52.21  ? 453 GLN A CG  1 
ATOM   3454  C  CD  . GLN A 1 453 ? 206.296 204.495 198.449 1.00 52.21  ? 453 GLN A CD  1 
ATOM   3455  O  OE1 . GLN A 1 453 ? 207.177 205.110 199.044 1.00 52.21  ? 453 GLN A OE1 1 
ATOM   3456  N  NE2 . GLN A 1 453 ? 206.400 203.207 198.150 1.00 52.21  ? 453 GLN A NE2 1 
ATOM   3457  N  N   . TYR A 1 454 ? 201.677 207.355 200.415 1.00 48.58  ? 454 TYR A N   1 
ATOM   3458  C  CA  . TYR A 1 454 ? 201.113 208.025 201.576 1.00 48.58  ? 454 TYR A CA  1 
ATOM   3459  C  C   . TYR A 1 454 ? 201.538 207.305 202.845 1.00 48.58  ? 454 TYR A C   1 
ATOM   3460  O  O   . TYR A 1 454 ? 201.551 206.074 202.894 1.00 48.58  ? 454 TYR A O   1 
ATOM   3461  C  CB  . TYR A 1 454 ? 199.591 208.065 201.491 1.00 48.58  ? 454 TYR A CB  1 
ATOM   3462  C  CG  . TYR A 1 454 ? 198.945 208.866 202.588 1.00 48.58  ? 454 TYR A CG  1 
ATOM   3463  C  CD1 . TYR A 1 454 ? 199.425 210.118 202.931 1.00 48.58  ? 454 TYR A CD1 1 
ATOM   3464  C  CD2 . TYR A 1 454 ? 197.852 208.372 203.278 1.00 48.58  ? 454 TYR A CD2 1 
ATOM   3465  C  CE1 . TYR A 1 454 ? 198.831 210.856 203.931 1.00 48.58  ? 454 TYR A CE1 1 
ATOM   3466  C  CE2 . TYR A 1 454 ? 197.254 209.098 204.275 1.00 48.58  ? 454 TYR A CE2 1 
ATOM   3467  C  CZ  . TYR A 1 454 ? 197.744 210.339 204.600 1.00 48.58  ? 454 TYR A CZ  1 
ATOM   3468  O  OH  . TYR A 1 454 ? 197.141 211.062 205.601 1.00 48.58  ? 454 TYR A OH  1 
ATOM   3469  N  N   . LEU A 1 455 ? 201.879 208.073 203.869 1.00 44.55  ? 455 LEU A N   1 
ATOM   3470  C  CA  . LEU A 1 455 ? 202.390 207.517 205.109 1.00 44.55  ? 455 LEU A CA  1 
ATOM   3471  C  C   . LEU A 1 455 ? 201.645 208.121 206.292 1.00 44.55  ? 455 LEU A C   1 
ATOM   3472  O  O   . LEU A 1 455 ? 201.319 209.310 206.291 1.00 44.55  ? 455 LEU A O   1 
ATOM   3473  C  CB  . LEU A 1 455 ? 203.887 207.773 205.238 1.00 44.55  ? 455 LEU A CB  1 
ATOM   3474  C  CG  . LEU A 1 455 ? 204.595 207.173 206.447 1.00 44.55  ? 455 LEU A CG  1 
ATOM   3475  C  CD1 . LEU A 1 455 ? 204.450 205.670 206.440 1.00 44.55  ? 455 LEU A CD1 1 
ATOM   3476  C  CD2 . LEU A 1 455 ? 206.055 207.560 206.455 1.00 44.55  ? 455 LEU A CD2 1 
ATOM   3477  N  N   . CYS A 1 456 ? 201.366 207.293 207.299 1.00 45.81  ? 456 CYS A N   1 
ATOM   3478  C  CA  . CYS A 1 456 ? 200.736 207.798 208.515 1.00 45.81  ? 456 CYS A CA  1 
ATOM   3479  C  C   . CYS A 1 456 ? 201.067 206.878 209.679 1.00 45.81  ? 456 CYS A C   1 
ATOM   3480  O  O   . CYS A 1 456 ? 201.559 205.766 209.493 1.00 45.81  ? 456 CYS A O   1 
ATOM   3481  C  CB  . CYS A 1 456 ? 199.221 207.937 208.354 1.00 45.81  ? 456 CYS A CB  1 
ATOM   3482  S  SG  . CYS A 1 456 ? 198.367 206.423 207.933 1.00 45.81  ? 456 CYS A SG  1 
ATOM   3483  N  N   . ARG A 1 457 ? 200.791 207.365 210.884 1.00 54.50  ? 457 ARG A N   1 
ATOM   3484  C  CA  . ARG A 1 457 ? 201.062 206.647 212.129 1.00 54.50  ? 457 ARG A CA  1 
ATOM   3485  C  C   . ARG A 1 457 ? 199.746 206.461 212.873 1.00 54.50  ? 457 ARG A C   1 
ATOM   3486  O  O   . ARG A 1 457 ? 199.172 207.432 213.373 1.00 54.50  ? 457 ARG A O   1 
ATOM   3487  C  CB  . ARG A 1 457 ? 202.059 207.415 212.985 1.00 54.50  ? 457 ARG A CB  1 
ATOM   3488  C  CG  . ARG A 1 457 ? 202.032 207.010 214.436 1.00 54.50  ? 457 ARG A CG  1 
ATOM   3489  C  CD  . ARG A 1 457 ? 203.061 207.762 215.229 1.00 54.50  ? 457 ARG A CD  1 
ATOM   3490  N  NE  . ARG A 1 457 ? 203.424 207.030 216.435 1.00 54.50  ? 457 ARG A NE  1 
ATOM   3491  C  CZ  . ARG A 1 457 ? 202.771 207.089 217.587 1.00 54.50  ? 457 ARG A CZ  1 
ATOM   3492  N  NH1 . ARG A 1 457 ? 201.682 207.822 217.725 1.00 54.50  ? 457 ARG A NH1 1 
ATOM   3493  N  NH2 . ARG A 1 457 ? 203.229 206.400 218.627 1.00 54.50  ? 457 ARG A NH2 1 
ATOM   3494  N  N   . ILE A 1 458 ? 199.251 205.227 212.964 1.00 57.08  ? 458 ILE A N   1 
ATOM   3495  C  CA  . ILE A 1 458 ? 197.943 205.050 213.580 1.00 57.08  ? 458 ILE A CA  1 
ATOM   3496  C  C   . ILE A 1 458 ? 198.060 205.108 215.096 1.00 57.08  ? 458 ILE A C   1 
ATOM   3497  O  O   . ILE A 1 458 ? 197.342 205.867 215.757 1.00 57.08  ? 458 ILE A O   1 
ATOM   3498  C  CB  . ILE A 1 458 ? 197.272 203.751 213.099 1.00 57.08  ? 458 ILE A CB  1 
ATOM   3499  C  CG1 . ILE A 1 458 ? 198.235 202.573 213.147 1.00 57.08  ? 458 ILE A CG1 1 
ATOM   3500  C  CG2 . ILE A 1 458 ? 196.763 203.915 211.694 1.00 57.08  ? 458 ILE A CG2 1 
ATOM   3501  C  CD1 . ILE A 1 458 ? 197.573 201.251 212.842 1.00 57.08  ? 458 ILE A CD1 1 
ATOM   3502  N  N   . GLU A 1 459 ? 198.982 204.340 215.669 1.00 61.25  ? 459 GLU A N   1 
ATOM   3503  C  CA  . GLU A 1 459 ? 199.098 204.305 217.120 1.00 61.25  ? 459 GLU A CA  1 
ATOM   3504  C  C   . GLU A 1 459 ? 200.383 203.597 217.512 1.00 61.25  ? 459 GLU A C   1 
ATOM   3505  O  O   . GLU A 1 459 ? 200.819 202.661 216.839 1.00 61.25  ? 459 GLU A O   1 
ATOM   3506  C  CB  . GLU A 1 459 ? 197.891 203.607 217.759 1.00 61.25  ? 459 GLU A CB  1 
ATOM   3507  C  CG  . GLU A 1 459 ? 197.695 202.170 217.324 1.00 61.25  ? 459 GLU A CG  1 
ATOM   3508  C  CD  . GLU A 1 459 ? 198.414 201.194 218.229 1.00 61.25  ? 459 GLU A CD  1 
ATOM   3509  O  OE1 . GLU A 1 459 ? 198.629 201.535 219.411 1.00 61.25  ? 459 GLU A OE1 1 
ATOM   3510  O  OE2 . GLU A 1 459 ? 198.762 200.089 217.765 1.00 61.25  ? 459 GLU A OE2 1 
ATOM   3511  N  N   . GLY A 1 460 ? 200.976 204.060 218.611 1.00 62.68  ? 460 GLY A N   1 
ATOM   3512  C  CA  . GLY A 1 460 ? 202.128 203.411 219.209 1.00 62.68  ? 460 GLY A CA  1 
ATOM   3513  C  C   . GLY A 1 460 ? 203.319 203.291 218.284 1.00 62.68  ? 460 GLY A C   1 
ATOM   3514  O  O   . GLY A 1 460 ? 203.994 204.280 217.985 1.00 62.68  ? 460 GLY A O   1 
ATOM   3515  N  N   . THR A 1 461 ? 203.597 202.066 217.842 1.00 62.56  ? 461 THR A N   1 
ATOM   3516  C  CA  . THR A 1 461 ? 204.622 201.807 216.842 1.00 62.56  ? 461 THR A CA  1 
ATOM   3517  C  C   . THR A 1 461 ? 204.029 201.180 215.587 1.00 62.56  ? 461 THR A C   1 
ATOM   3518  O  O   . THR A 1 461 ? 204.708 200.414 214.891 1.00 62.56  ? 461 THR A O   1 
ATOM   3519  C  CB  . THR A 1 461 ? 205.722 200.918 217.421 1.00 62.56  ? 461 THR A CB  1 
ATOM   3520  O  OG1 . THR A 1 461 ? 205.156 199.675 217.854 1.00 62.56  ? 461 THR A OG1 1 
ATOM   3521  C  CG2 . THR A 1 461 ? 206.380 201.606 218.606 1.00 62.56  ? 461 THR A CG2 1 
ATOM   3522  N  N   . GLN A 1 462 ? 202.775 201.493 215.280 1.00 58.16  ? 462 GLN A N   1 
ATOM   3523  C  CA  . GLN A 1 462 ? 202.115 200.993 214.082 1.00 58.16  ? 462 GLN A CA  1 
ATOM   3524  C  C   . GLN A 1 462 ? 201.950 202.128 213.077 1.00 58.16  ? 462 GLN A C   1 
ATOM   3525  O  O   . GLN A 1 462 ? 201.302 203.143 213.368 1.00 58.16  ? 462 GLN A O   1 
ATOM   3526  C  CB  . GLN A 1 462 ? 200.761 200.372 214.422 1.00 58.16  ? 462 GLN A CB  1 
ATOM   3527  C  CG  . GLN A 1 462 ? 200.851 199.061 215.171 1.00 58.16  ? 462 GLN A CG  1 
ATOM   3528  C  CD  . GLN A 1 462 ? 199.507 198.376 215.301 1.00 58.16  ? 462 GLN A CD  1 
ATOM   3529  O  OE1 . GLN A 1 462 ? 198.671 198.448 214.403 1.00 58.16  ? 462 GLN A OE1 1 
ATOM   3530  N  NE2 . GLN A 1 462 ? 199.289 197.712 216.427 1.00 58.16  ? 462 GLN A NE2 1 
ATOM   3531  N  N   . PHE A 1 463 ? 202.536 201.950 211.900 1.00 47.55  ? 463 PHE A N   1 
ATOM   3532  C  CA  . PHE A 1 463 ? 202.404 202.866 210.785 1.00 47.55  ? 463 PHE A CA  1 
ATOM   3533  C  C   . PHE A 1 463 ? 201.575 202.215 209.689 1.00 47.55  ? 463 PHE A C   1 
ATOM   3534  O  O   . PHE A 1 463 ? 201.397 200.998 209.648 1.00 47.55  ? 463 PHE A O   1 
ATOM   3535  C  CB  . PHE A 1 463 ? 203.778 203.270 210.250 1.00 47.55  ? 463 PHE A CB  1 
ATOM   3536  C  CG  . PHE A 1 463 ? 204.684 203.859 211.285 1.00 47.55  ? 463 PHE A CG  1 
ATOM   3537  C  CD1 . PHE A 1 463 ? 205.441 203.055 212.100 1.00 47.55  ? 463 PHE A CD1 1 
ATOM   3538  C  CD2 . PHE A 1 463 ? 204.790 205.226 211.427 1.00 47.55  ? 463 PHE A CD2 1 
ATOM   3539  C  CE1 . PHE A 1 463 ? 206.280 203.603 213.046 1.00 47.55  ? 463 PHE A CE1 1 
ATOM   3540  C  CE2 . PHE A 1 463 ? 205.623 205.778 212.369 1.00 47.55  ? 463 PHE A CE2 1 
ATOM   3541  C  CZ  . PHE A 1 463 ? 206.370 204.969 213.177 1.00 47.55  ? 463 PHE A CZ  1 
ATOM   3542  N  N   . VAL A 1 464 ? 201.052 203.043 208.800 1.00 43.15  ? 464 VAL A N   1 
ATOM   3543  C  CA  . VAL A 1 464 ? 200.334 202.582 207.622 1.00 43.15  ? 464 VAL A CA  1 
ATOM   3544  C  C   . VAL A 1 464 ? 200.930 203.275 206.408 1.00 43.15  ? 464 VAL A C   1 
ATOM   3545  O  O   . VAL A 1 464 ? 201.114 204.498 206.405 1.00 43.15  ? 464 VAL A O   1 
ATOM   3546  C  CB  . VAL A 1 464 ? 198.820 202.860 207.710 1.00 43.15  ? 464 VAL A CB  1 
ATOM   3547  C  CG1 . VAL A 1 464 ? 198.131 202.446 206.428 1.00 43.15  ? 464 VAL A CG1 1 
ATOM   3548  C  CG2 . VAL A 1 464 ? 198.216 202.142 208.884 1.00 43.15  ? 464 VAL A CG2 1 
ATOM   3549  N  N   . LEU A 1 465 ? 201.242 202.489 205.383 1.00 43.93  ? 465 LEU A N   1 
ATOM   3550  C  CA  . LEU A 1 465 ? 201.758 203.003 204.121 1.00 43.93  ? 465 LEU A CA  1 
ATOM   3551  C  C   . LEU A 1 465 ? 200.771 202.621 203.031 1.00 43.93  ? 465 LEU A C   1 
ATOM   3552  O  O   . LEU A 1 465 ? 200.557 201.434 202.773 1.00 43.93  ? 465 LEU A O   1 
ATOM   3553  C  CB  . LEU A 1 465 ? 203.148 202.445 203.832 1.00 43.93  ? 465 LEU A CB  1 
ATOM   3554  C  CG  . LEU A 1 465 ? 203.956 203.147 202.745 1.00 43.93  ? 465 LEU A CG  1 
ATOM   3555  C  CD1 . LEU A 1 465 ? 205.421 203.191 203.136 1.00 43.93  ? 465 LEU A CD1 1 
ATOM   3556  C  CD2 . LEU A 1 465 ? 203.780 202.445 201.415 1.00 43.93  ? 465 LEU A CD2 1 
ATOM   3557  N  N   . VAL A 1 466 ? 200.165 203.614 202.396 1.00 40.68  ? 466 VAL A N   1 
ATOM   3558  C  CA  . VAL A 1 466 ? 199.162 203.372 201.371 1.00 40.68  ? 466 VAL A CA  1 
ATOM   3559  C  C   . VAL A 1 466 ? 199.753 203.737 200.019 1.00 40.68  ? 466 VAL A C   1 
ATOM   3560  O  O   . VAL A 1 466 ? 200.357 204.805 199.857 1.00 40.68  ? 466 VAL A O   1 
ATOM   3561  C  CB  . VAL A 1 466 ? 197.875 204.159 201.650 1.00 40.68  ? 466 VAL A CB  1 
ATOM   3562  C  CG1 . VAL A 1 466 ? 196.867 203.923 200.558 1.00 40.68  ? 466 VAL A CG1 1 
ATOM   3563  C  CG2 . VAL A 1 466 ? 197.303 203.768 202.989 1.00 40.68  ? 466 VAL A CG2 1 
ATOM   3564  N  N   . SER A 1 467 ? 199.603 202.834 199.055 1.00 47.31  ? 467 SER A N   1 
ATOM   3565  C  CA  . SER A 1 467 ? 200.114 203.045 197.709 1.00 47.31  ? 467 SER A CA  1 
ATOM   3566  C  C   . SER A 1 467 ? 199.069 202.582 196.706 1.00 47.31  ? 467 SER A C   1 
ATOM   3567  O  O   . SER A 1 467 ? 197.974 202.151 197.074 1.00 47.31  ? 467 SER A O   1 
ATOM   3568  C  CB  . SER A 1 467 ? 201.446 202.324 197.500 1.00 47.31  ? 467 SER A CB  1 
ATOM   3569  O  OG  . SER A 1 467 ? 201.919 202.505 196.179 1.00 47.31  ? 467 SER A OG  1 
ATOM   3570  N  N   . LEU A 1 468 ? 199.407 202.673 195.423 1.00 52.14  ? 468 LEU A N   1 
ATOM   3571  C  CA  . LEU A 1 468 ? 198.459 202.345 194.367 1.00 52.14  ? 468 LEU A CA  1 
ATOM   3572  C  C   . LEU A 1 468 ? 198.997 201.315 193.382 1.00 52.14  ? 468 LEU A C   1 
ATOM   3573  O  O   . LEU A 1 468 ? 198.399 201.124 192.317 1.00 52.14  ? 468 LEU A O   1 
ATOM   3574  C  CB  . LEU A 1 468 ? 198.040 203.613 193.621 1.00 52.14  ? 468 LEU A CB  1 
ATOM   3575  C  CG  . LEU A 1 468 ? 197.155 204.551 194.434 1.00 52.14  ? 468 LEU A CG  1 
ATOM   3576  C  CD1 . LEU A 1 468 ? 196.840 205.804 193.640 1.00 52.14  ? 468 LEU A CD1 1 
ATOM   3577  C  CD2 . LEU A 1 468 ? 195.885 203.831 194.833 1.00 52.14  ? 468 LEU A CD2 1 
ATOM   3578  N  N   . GLU A 1 469 ? 200.099 200.647 193.703 1.00 57.83  ? 469 GLU A N   1 
ATOM   3579  C  CA  . GLU A 1 469 ? 200.610 199.596 192.842 1.00 57.83  ? 469 GLU A CA  1 
ATOM   3580  C  C   . GLU A 1 469 ? 199.711 198.365 192.916 1.00 57.83  ? 469 GLU A C   1 
ATOM   3581  O  O   . GLU A 1 469 ? 198.919 198.195 193.844 1.00 57.83  ? 469 GLU A O   1 
ATOM   3582  C  CB  . GLU A 1 469 ? 202.038 199.230 193.235 1.00 57.83  ? 469 GLU A CB  1 
ATOM   3583  C  CG  . GLU A 1 469 ? 202.936 200.426 193.487 1.00 57.83  ? 469 GLU A CG  1 
ATOM   3584  C  CD  . GLU A 1 469 ? 202.813 201.485 192.410 1.00 57.83  ? 469 GLU A CD  1 
ATOM   3585  O  OE1 . GLU A 1 469 ? 203.115 201.181 191.237 1.00 57.83  ? 469 GLU A OE1 1 
ATOM   3586  O  OE2 . GLU A 1 469 ? 202.415 202.623 192.737 1.00 57.83  ? 469 GLU A OE2 1 
ATOM   3587  N  N   . ASN A 1 470 ? 199.827 197.506 191.905 1.00 61.24  ? 470 ASN A N   1 
ATOM   3588  C  CA  . ASN A 1 470 ? 199.034 196.284 191.883 1.00 61.24  ? 470 ASN A CA  1 
ATOM   3589  C  C   . ASN A 1 470 ? 199.787 195.034 191.450 1.00 61.24  ? 470 ASN A C   1 
ATOM   3590  O  O   . ASN A 1 470 ? 199.268 193.935 191.666 1.00 61.24  ? 470 ASN A O   1 
ATOM   3591  C  CB  . ASN A 1 470 ? 197.816 196.467 190.973 1.00 61.24  ? 470 ASN A CB  1 
ATOM   3592  C  CG  . ASN A 1 470 ? 196.792 197.394 191.570 1.00 61.24  ? 470 ASN A CG  1 
ATOM   3593  O  OD1 . ASN A 1 470 ? 196.224 197.111 192.622 1.00 61.24  ? 470 ASN A OD1 1 
ATOM   3594  N  ND2 . ASN A 1 470 ? 196.551 198.517 190.906 1.00 61.24  ? 470 ASN A ND2 1 
ATOM   3595  N  N   . ASP A 1 471 ? 200.972 195.145 190.857 1.00 64.16  ? 471 ASP A N   1 
ATOM   3596  C  CA  . ASP A 1 471 ? 201.733 193.975 190.443 1.00 64.16  ? 471 ASP A CA  1 
ATOM   3597  C  C   . ASP A 1 471 ? 202.488 193.399 191.630 1.00 64.16  ? 471 ASP A C   1 
ATOM   3598  O  O   . ASP A 1 471 ? 203.200 194.119 192.337 1.00 64.16  ? 471 ASP A O   1 
ATOM   3599  C  CB  . ASP A 1 471 ? 202.710 194.333 189.325 1.00 64.16  ? 471 ASP A CB  1 
ATOM   3600  C  CG  . ASP A 1 471 ? 203.278 193.109 188.636 1.00 64.16  ? 471 ASP A CG  1 
ATOM   3601  O  OD1 . ASP A 1 471 ? 204.231 192.511 189.175 1.00 64.16  ? 471 ASP A OD1 1 
ATOM   3602  O  OD2 . ASP A 1 471 ? 202.766 192.742 187.558 1.00 64.16  ? 471 ASP A OD2 1 
ATOM   3603  N  N   . VAL A 1 472 ? 202.341 192.086 191.831 1.00 59.70  ? 472 VAL A N   1 
ATOM   3604  C  CA  . VAL A 1 472 ? 202.874 191.447 193.032 1.00 59.70  ? 472 VAL A CA  1 
ATOM   3605  C  C   . VAL A 1 472 ? 204.386 191.605 193.121 1.00 59.70  ? 472 VAL A C   1 
ATOM   3606  O  O   . VAL A 1 472 ? 204.943 191.677 194.219 1.00 59.70  ? 472 VAL A O   1 
ATOM   3607  C  CB  . VAL A 1 472 ? 202.451 189.969 193.080 1.00 59.70  ? 472 VAL A CB  1 
ATOM   3608  C  CG1 . VAL A 1 472 ? 202.806 189.363 194.425 1.00 59.70  ? 472 VAL A CG1 1 
ATOM   3609  C  CG2 . VAL A 1 472 ? 200.963 189.849 192.814 1.00 59.70  ? 472 VAL A CG2 1 
ATOM   3610  N  N   . SER A 1 473 ? 205.073 191.669 191.982 1.00 62.11  ? 473 SER A N   1 
ATOM   3611  C  CA  . SER A 1 473 ? 206.505 191.940 192.013 1.00 62.11  ? 473 SER A CA  1 
ATOM   3612  C  C   . SER A 1 473 ? 206.786 193.309 192.622 1.00 62.11  ? 473 SER A C   1 
ATOM   3613  O  O   . SER A 1 473 ? 207.652 193.449 193.493 1.00 62.11  ? 473 SER A O   1 
ATOM   3614  C  CB  . SER A 1 473 ? 207.087 191.840 190.603 1.00 62.11  ? 473 SER A CB  1 
ATOM   3615  O  OG  . SER A 1 473 ? 206.564 192.853 189.761 1.00 62.11  ? 473 SER A OG  1 
ATOM   3616  N  N   . ASN A 1 474 ? 206.044 194.331 192.190 1.00 62.67  ? 474 ASN A N   1 
ATOM   3617  C  CA  . ASN A 1 474 ? 206.237 195.666 192.746 1.00 62.67  ? 474 ASN A CA  1 
ATOM   3618  C  C   . ASN A 1 474 ? 205.892 195.698 194.227 1.00 62.67  ? 474 ASN A C   1 
ATOM   3619  O  O   . ASN A 1 474 ? 206.591 196.334 195.024 1.00 62.67  ? 474 ASN A O   1 
ATOM   3620  C  CB  . ASN A 1 474 ? 205.390 196.681 191.980 1.00 62.67  ? 474 ASN A CB  1 
ATOM   3621  C  CG  . ASN A 1 474 ? 205.846 196.861 190.547 1.00 62.67  ? 474 ASN A CG  1 
ATOM   3622  O  OD1 . ASN A 1 474 ? 205.330 196.218 189.633 1.00 62.67  ? 474 ASN A OD1 1 
ATOM   3623  N  ND2 . ASN A 1 474 ? 206.820 197.741 190.342 1.00 62.67  ? 474 ASN A ND2 1 
ATOM   3624  N  N   . ILE A 1 475 ? 204.811 195.018 194.609 1.00 56.35  ? 475 ILE A N   1 
ATOM   3625  C  CA  . ILE A 1 475 ? 204.392 194.991 196.008 1.00 56.35  ? 475 ILE A CA  1 
ATOM   3626  C  C   . ILE A 1 475 ? 205.459 194.322 196.867 1.00 56.35  ? 475 ILE A C   1 
ATOM   3627  O  O   . ILE A 1 475 ? 205.814 194.808 197.950 1.00 56.35  ? 475 ILE A O   1 
ATOM   3628  C  CB  . ILE A 1 475 ? 203.032 194.285 196.134 1.00 56.35  ? 475 ILE A CB  1 
ATOM   3629  C  CG1 . ILE A 1 475 ? 202.045 194.890 195.143 1.00 56.35  ? 475 ILE A CG1 1 
ATOM   3630  C  CG2 . ILE A 1 475 ? 202.502 194.404 197.540 1.00 56.35  ? 475 ILE A CG2 1 
ATOM   3631  C  CD1 . ILE A 1 475 ? 201.029 193.924 194.631 1.00 56.35  ? 475 ILE A CD1 1 
ATOM   3632  N  N   . THR A 1 476 ? 205.992 193.198 196.389 1.00 57.73  ? 476 THR A N   1 
ATOM   3633  C  CA  . THR A 1 476 ? 207.056 192.518 197.111 1.00 57.73  ? 476 THR A CA  1 
ATOM   3634  C  C   . THR A 1 476 ? 208.285 193.401 197.212 1.00 57.73  ? 476 THR A C   1 
ATOM   3635  O  O   . THR A 1 476 ? 208.958 193.419 198.246 1.00 57.73  ? 476 THR A O   1 
ATOM   3636  C  CB  . THR A 1 476 ? 207.405 191.201 196.420 1.00 57.73  ? 476 THR A CB  1 
ATOM   3637  O  OG1 . THR A 1 476 ? 206.205 190.472 196.135 1.00 57.73  ? 476 THR A OG1 1 
ATOM   3638  C  CG2 . THR A 1 476 ? 208.306 190.359 197.306 1.00 57.73  ? 476 THR A CG2 1 
ATOM   3639  N  N   . GLN A 1 477 ? 208.598 194.137 196.143 1.00 62.50  ? 477 GLN A N   1 
ATOM   3640  C  CA  . GLN A 1 477 ? 209.760 195.018 196.164 1.00 62.50  ? 477 GLN A CA  1 
ATOM   3641  C  C   . GLN A 1 477 ? 209.598 196.110 197.214 1.00 62.50  ? 477 GLN A C   1 
ATOM   3642  O  O   . GLN A 1 477 ? 210.529 196.402 197.974 1.00 62.50  ? 477 GLN A O   1 
ATOM   3643  C  CB  . GLN A 1 477 ? 209.977 195.624 194.777 1.00 62.50  ? 477 GLN A CB  1 
ATOM   3644  C  CG  . GLN A 1 477 ? 211.349 196.246 194.569 1.00 62.50  ? 477 GLN A CG  1 
ATOM   3645  C  CD  . GLN A 1 477 ? 211.378 197.725 194.900 1.00 62.50  ? 477 GLN A CD  1 
ATOM   3646  O  OE1 . GLN A 1 477 ? 210.335 198.353 195.081 1.00 62.50  ? 477 GLN A OE1 1 
ATOM   3647  N  NE2 . GLN A 1 477 ? 212.578 198.291 194.976 1.00 62.50  ? 477 GLN A NE2 1 
ATOM   3648  N  N   . ILE A 1 478 ? 208.413 196.720 197.272 1.00 59.51  ? 478 ILE A N   1 
ATOM   3649  C  CA  . ILE A 1 478 ? 208.157 197.751 198.273 1.00 59.51  ? 478 ILE A CA  1 
ATOM   3650  C  C   . ILE A 1 478 ? 208.289 197.165 199.670 1.00 59.51  ? 478 ILE A C   1 
ATOM   3651  O  O   . ILE A 1 478 ? 208.921 197.754 200.556 1.00 59.51  ? 478 ILE A O   1 
ATOM   3652  C  CB  . ILE A 1 478 ? 206.770 198.382 198.060 1.00 59.51  ? 478 ILE A CB  1 
ATOM   3653  C  CG1 . ILE A 1 478 ? 206.674 199.017 196.680 1.00 59.51  ? 478 ILE A CG1 1 
ATOM   3654  C  CG2 . ILE A 1 478 ? 206.496 199.429 199.112 1.00 59.51  ? 478 ILE A CG2 1 
ATOM   3655  C  CD1 . ILE A 1 478 ? 205.261 199.154 196.182 1.00 59.51  ? 478 ILE A CD1 1 
ATOM   3656  N  N   . ALA A 1 479 ? 207.696 195.989 199.885 1.00 59.78  ? 479 ALA A N   1 
ATOM   3657  C  CA  . ALA A 1 479 ? 207.750 195.375 201.206 1.00 59.78  ? 479 ALA A CA  1 
ATOM   3658  C  C   . ALA A 1 479 ? 209.184 195.072 201.611 1.00 59.78  ? 479 ALA A C   1 
ATOM   3659  O  O   . ALA A 1 479 ? 209.586 195.331 202.751 1.00 59.78  ? 479 ALA A O   1 
ATOM   3660  C  CB  . ALA A 1 479 ? 206.905 194.103 201.227 1.00 59.78  ? 479 ALA A CB  1 
ATOM   3661  N  N   . ASP A 1 480 ? 209.973 194.534 200.683 1.00 61.59  ? 480 ASP A N   1 
ATOM   3662  C  CA  . ASP A 1 480 ? 211.352 194.184 200.992 1.00 61.59  ? 480 ASP A CA  1 
ATOM   3663  C  C   . ASP A 1 480 ? 212.187 195.423 201.268 1.00 61.59  ? 480 ASP A C   1 
ATOM   3664  O  O   . ASP A 1 480 ? 213.046 195.413 202.158 1.00 61.59  ? 480 ASP A O   1 
ATOM   3665  C  CB  . ASP A 1 480 ? 211.952 193.373 199.849 1.00 61.59  ? 480 ASP A CB  1 
ATOM   3666  C  CG  . ASP A 1 480 ? 212.992 192.385 200.324 1.00 61.59  ? 480 ASP A CG  1 
ATOM   3667  O  OD1 . ASP A 1 480 ? 213.736 192.718 201.270 1.00 61.59  ? 480 ASP A OD1 1 
ATOM   3668  O  OD2 . ASP A 1 480 ? 213.068 191.276 199.754 1.00 61.59  ? 480 ASP A OD2 1 
ATOM   3669  N  N   . GLU A 1 481 ? 211.957 196.502 200.517 1.00 60.89  ? 481 GLU A N   1 
ATOM   3670  C  CA  . GLU A 1 481 ? 212.729 197.714 200.761 1.00 60.89  ? 481 GLU A CA  1 
ATOM   3671  C  C   . GLU A 1 481 ? 212.355 198.332 202.101 1.00 60.89  ? 481 GLU A C   1 
ATOM   3672  O  O   . GLU A 1 481 ? 213.222 198.846 202.819 1.00 60.89  ? 481 GLU A O   1 
ATOM   3673  C  CB  . GLU A 1 481 ? 212.551 198.704 199.606 1.00 60.89  ? 481 GLU A CB  1 
ATOM   3674  C  CG  . GLU A 1 481 ? 211.337 199.612 199.682 1.00 60.89  ? 481 GLU A CG  1 
ATOM   3675  C  CD  . GLU A 1 481 ? 211.428 200.774 198.714 1.00 60.89  ? 481 GLU A CD  1 
ATOM   3676  O  OE1 . GLU A 1 481 ? 212.542 201.309 198.530 1.00 60.89  ? 481 GLU A OE1 1 
ATOM   3677  O  OE2 . GLU A 1 481 ? 210.387 201.154 198.137 1.00 60.89  ? 481 GLU A OE2 1 
ATOM   3678  N  N   . LEU A 1 482 ? 211.075 198.261 202.474 1.00 60.29  ? 482 LEU A N   1 
ATOM   3679  C  CA  . LEU A 1 482 ? 210.675 198.715 203.800 1.00 60.29  ? 482 LEU A CA  1 
ATOM   3680  C  C   . LEU A 1 482 ? 211.330 197.868 204.879 1.00 60.29  ? 482 LEU A C   1 
ATOM   3681  O  O   . LEU A 1 482 ? 211.753 198.387 205.916 1.00 60.29  ? 482 LEU A O   1 
ATOM   3682  C  CB  . LEU A 1 482 ? 209.156 198.672 203.935 1.00 60.29  ? 482 LEU A CB  1 
ATOM   3683  C  CG  . LEU A 1 482 ? 208.371 199.710 203.138 1.00 60.29  ? 482 LEU A CG  1 
ATOM   3684  C  CD1 . LEU A 1 482 ? 206.891 199.374 203.149 1.00 60.29  ? 482 LEU A CD1 1 
ATOM   3685  C  CD2 . LEU A 1 482 ? 208.611 201.099 203.681 1.00 60.29  ? 482 LEU A CD2 1 
ATOM   3686  N  N   . ARG A 1 483 ? 211.414 196.558 204.652 1.00 63.01  ? 483 ARG A N   1 
ATOM   3687  C  CA  . ARG A 1 483 ? 212.036 195.677 205.633 1.00 63.01  ? 483 ARG A CA  1 
ATOM   3688  C  C   . ARG A 1 483 ? 213.519 195.985 205.798 1.00 63.01  ? 483 ARG A C   1 
ATOM   3689  O  O   . ARG A 1 483 ? 214.039 195.991 206.920 1.00 63.01  ? 483 ARG A O   1 
ATOM   3690  C  CB  . ARG A 1 483 ? 211.830 194.216 205.229 1.00 63.01  ? 483 ARG A CB  1 
ATOM   3691  C  CG  . ARG A 1 483 ? 212.160 193.221 206.329 1.00 63.01  ? 483 ARG A CG  1 
ATOM   3692  C  CD  . ARG A 1 483 ? 211.896 191.789 205.892 1.00 63.01  ? 483 ARG A CD  1 
ATOM   3693  N  NE  . ARG A 1 483 ? 212.952 191.271 205.030 1.00 63.01  ? 483 ARG A NE  1 
ATOM   3694  C  CZ  . ARG A 1 483 ? 212.833 191.101 203.720 1.00 63.01  ? 483 ARG A CZ  1 
ATOM   3695  N  NH1 . ARG A 1 483 ? 211.710 191.393 203.085 1.00 63.01  ? 483 ARG A NH1 1 
ATOM   3696  N  NH2 . ARG A 1 483 ? 213.866 190.626 203.031 1.00 63.01  ? 483 ARG A NH2 1 
ATOM   3697  N  N   . ASN A 1 484 ? 214.219 196.246 204.696 1.00 64.56  ? 484 ASN A N   1 
ATOM   3698  C  CA  . ASN A 1 484 ? 215.664 196.401 204.784 1.00 64.56  ? 484 ASN A CA  1 
ATOM   3699  C  C   . ASN A 1 484 ? 216.116 197.847 204.955 1.00 64.56  ? 484 ASN A C   1 
ATOM   3700  O  O   . ASN A 1 484 ? 217.324 198.083 205.063 1.00 64.56  ? 484 ASN A O   1 
ATOM   3701  C  CB  . ASN A 1 484 ? 216.340 195.775 203.559 1.00 64.56  ? 484 ASN A CB  1 
ATOM   3702  C  CG  . ASN A 1 484 ? 215.944 196.439 202.251 1.00 64.56  ? 484 ASN A CG  1 
ATOM   3703  O  OD1 . ASN A 1 484 ? 215.546 197.601 202.215 1.00 64.56  ? 484 ASN A OD1 1 
ATOM   3704  N  ND2 . ASN A 1 484 ? 216.052 195.690 201.160 1.00 64.56  ? 484 ASN A ND2 1 
ATOM   3705  N  N   . VAL A 1 485 ? 215.198 198.818 204.978 1.00 63.50  ? 485 VAL A N   1 
ATOM   3706  C  CA  . VAL A 1 485 ? 215.613 200.189 205.267 1.00 63.50  ? 485 VAL A CA  1 
ATOM   3707  C  C   . VAL A 1 485 ? 216.056 200.308 206.720 1.00 63.50  ? 485 VAL A C   1 
ATOM   3708  O  O   . VAL A 1 485 ? 216.725 201.272 207.109 1.00 63.50  ? 485 VAL A O   1 
ATOM   3709  C  CB  . VAL A 1 485 ? 214.482 201.181 204.937 1.00 63.50  ? 485 VAL A CB  1 
ATOM   3710  C  CG1 . VAL A 1 485 ? 213.344 201.034 205.919 1.00 63.50  ? 485 VAL A CG1 1 
ATOM   3711  C  CG2 . VAL A 1 485 ? 215.005 202.608 204.895 1.00 63.50  ? 485 VAL A CG2 1 
ATOM   3712  N  N   . VAL A 1 486 ? 215.689 199.324 207.548 1.00 64.73  ? 486 VAL A N   1 
ATOM   3713  C  CA  . VAL A 1 486 ? 216.117 199.295 208.944 1.00 64.73  ? 486 VAL A CA  1 
ATOM   3714  C  C   . VAL A 1 486 ? 217.230 198.289 209.182 1.00 64.73  ? 486 VAL A C   1 
ATOM   3715  O  O   . VAL A 1 486 ? 217.653 198.109 210.332 1.00 64.73  ? 486 VAL A O   1 
ATOM   3716  C  CB  . VAL A 1 486 ? 214.895 198.987 209.835 1.00 64.73  ? 486 VAL A CB  1 
ATOM   3717  C  CG1 . VAL A 1 486 ? 214.518 197.512 209.735 1.00 64.73  ? 486 VAL A CG1 1 
ATOM   3718  C  CG2 . VAL A 1 486 ? 215.124 199.426 211.283 1.00 64.73  ? 486 VAL A CG2 1 
ATOM   3719  N  N   . SER A 1 487 ? 217.737 197.649 208.124 1.00 68.02  ? 487 SER A N   1 
ATOM   3720  C  CA  . SER A 1 487 ? 218.676 196.539 208.270 1.00 68.02  ? 487 SER A CA  1 
ATOM   3721  C  C   . SER A 1 487 ? 219.866 196.912 209.139 1.00 68.02  ? 487 SER A C   1 
ATOM   3722  O  O   . SER A 1 487 ? 220.292 196.135 209.999 1.00 68.02  ? 487 SER A O   1 
ATOM   3723  C  CB  . SER A 1 487 ? 219.151 196.076 206.891 1.00 68.02  ? 487 SER A CB  1 
ATOM   3724  O  OG  . SER A 1 487 ? 219.789 197.130 206.196 1.00 68.02  ? 487 SER A OG  1 
ATOM   3725  N  N   . LYS A 1 488 ? 220.412 198.094 208.929 1.00 73.25  ? 488 LYS A N   1 
ATOM   3726  C  CA  . LYS A 1 488 ? 221.447 198.593 209.820 1.00 73.25  ? 488 LYS A CA  1 
ATOM   3727  C  C   . LYS A 1 488 ? 220.812 198.940 211.159 1.00 73.25  ? 488 LYS A C   1 
ATOM   3728  O  O   . LYS A 1 488 ? 219.856 199.726 211.192 1.00 73.25  ? 488 LYS A O   1 
ATOM   3729  C  CB  . LYS A 1 488 ? 222.131 199.816 209.218 1.00 73.25  ? 488 LYS A CB  1 
ATOM   3730  C  CG  . LYS A 1 488 ? 223.370 200.268 209.971 1.00 73.25  ? 488 LYS A CG  1 
ATOM   3731  C  CD  . LYS A 1 488 ? 224.069 201.407 209.249 1.00 73.25  ? 488 LYS A CD  1 
ATOM   3732  C  CE  . LYS A 1 488 ? 225.287 201.885 210.021 1.00 73.25  ? 488 LYS A CE  1 
ATOM   3733  N  NZ  . LYS A 1 488 ? 226.404 200.903 209.953 1.00 73.25  ? 488 LYS A NZ  1 
ATOM   3734  N  N   . PRO A 1 489 ? 221.282 198.376 212.269 1.00 75.82  ? 489 PRO A N   1 
ATOM   3735  C  CA  . PRO A 1 489 ? 220.693 198.711 213.570 1.00 75.82  ? 489 PRO A CA  1 
ATOM   3736  C  C   . PRO A 1 489 ? 220.814 200.198 213.870 1.00 75.82  ? 489 PRO A C   1 
ATOM   3737  O  O   . PRO A 1 489 ? 221.799 200.846 213.514 1.00 75.82  ? 489 PRO A O   1 
ATOM   3738  C  CB  . PRO A 1 489 ? 221.507 197.865 214.555 1.00 75.82  ? 489 PRO A CB  1 
ATOM   3739  C  CG  . PRO A 1 489 ? 222.026 196.730 213.733 1.00 75.82  ? 489 PRO A CG  1 
ATOM   3740  C  CD  . PRO A 1 489 ? 222.283 197.302 212.370 1.00 75.82  ? 489 PRO A CD  1 
ATOM   3741  N  N   . ILE A 1 490 ? 219.791 200.735 214.533 1.00 79.04  ? 490 ILE A N   1 
ATOM   3742  C  CA  . ILE A 1 490 ? 219.728 202.162 214.818 1.00 79.04  ? 490 ILE A CA  1 
ATOM   3743  C  C   . ILE A 1 490 ? 220.793 202.506 215.846 1.00 79.04  ? 490 ILE A C   1 
ATOM   3744  O  O   . ILE A 1 490 ? 220.646 202.209 217.036 1.00 79.04  ? 490 ILE A O   1 
ATOM   3745  C  CB  . ILE A 1 490 ? 218.330 202.576 215.309 1.00 79.04  ? 490 ILE A CB  1 
ATOM   3746  C  CG1 . ILE A 1 490 ? 217.286 202.311 214.222 1.00 79.04  ? 490 ILE A CG1 1 
ATOM   3747  C  CG2 . ILE A 1 490 ? 218.323 204.036 215.731 1.00 79.04  ? 490 ILE A CG2 1 
ATOM   3748  C  CD1 . ILE A 1 490 ? 217.531 203.062 212.936 1.00 79.04  ? 490 ILE A CD1 1 
ATOM   3749  N  N   . MET A 1 491 ? 221.869 203.136 215.392 1.00 81.50  ? 491 MET A N   1 
ATOM   3750  C  CA  . MET A 1 491 ? 222.991 203.450 216.263 1.00 81.50  ? 491 MET A CA  1 
ATOM   3751  C  C   . MET A 1 491 ? 222.666 204.688 217.086 1.00 81.50  ? 491 MET A C   1 
ATOM   3752  O  O   . MET A 1 491 ? 222.659 205.806 216.562 1.00 81.50  ? 491 MET A O   1 
ATOM   3753  C  CB  . MET A 1 491 ? 224.259 203.668 215.441 1.00 81.50  ? 491 MET A CB  1 
ATOM   3754  C  CG  . MET A 1 491 ? 224.744 202.430 214.712 1.00 81.50  ? 491 MET A CG  1 
ATOM   3755  S  SD  . MET A 1 491 ? 224.503 200.923 215.669 1.00 81.50  ? 491 MET A SD  1 
ATOM   3756  C  CE  . MET A 1 491 ? 224.691 199.683 214.390 1.00 81.50  ? 491 MET A CE  1 
ATOM   3757  N  N   . ILE A 1 492 ? 222.395 204.488 218.372 1.00 81.07  ? 492 ILE A N   1 
ATOM   3758  C  CA  . ILE A 1 492 ? 222.202 205.587 219.310 1.00 81.07  ? 492 ILE A CA  1 
ATOM   3759  C  C   . ILE A 1 492 ? 223.164 205.383 220.474 1.00 81.07  ? 492 ILE A C   1 
ATOM   3760  O  O   . ILE A 1 492 ? 223.188 204.312 221.091 1.00 81.07  ? 492 ILE A O   1 
ATOM   3761  C  CB  . ILE A 1 492 ? 220.734 205.695 219.783 1.00 81.07  ? 492 ILE A CB  1 
ATOM   3762  C  CG1 . ILE A 1 492 ? 220.552 206.905 220.694 1.00 81.07  ? 492 ILE A CG1 1 
ATOM   3763  C  CG2 . ILE A 1 492 ? 220.245 204.407 220.436 1.00 81.07  ? 492 ILE A CG2 1 
ATOM   3764  C  CD1 . ILE A 1 492 ? 220.620 208.219 219.959 1.00 81.07  ? 492 ILE A CD1 1 
ATOM   3765  N  N   . ASP A 1 493 ? 223.989 206.397 220.740 1.00 83.56  ? 493 ASP A N   1 
ATOM   3766  C  CA  . ASP A 1 493 ? 225.045 206.316 221.750 1.00 83.56  ? 493 ASP A CA  1 
ATOM   3767  C  C   . ASP A 1 493 ? 225.922 205.087 221.513 1.00 83.56  ? 493 ASP A C   1 
ATOM   3768  O  O   . ASP A 1 493 ? 226.372 204.429 222.453 1.00 83.56  ? 493 ASP A O   1 
ATOM   3769  C  CB  . ASP A 1 493 ? 224.451 206.315 223.163 1.00 83.56  ? 493 ASP A CB  1 
ATOM   3770  C  CG  . ASP A 1 493 ? 225.494 206.545 224.245 1.00 83.56  ? 493 ASP A CG  1 
ATOM   3771  O  OD1 . ASP A 1 493 ? 226.688 206.698 223.913 1.00 83.56  ? 493 ASP A OD1 1 
ATOM   3772  O  OD2 . ASP A 1 493 ? 225.114 206.572 225.435 1.00 83.56  ? 493 ASP A OD2 1 
ATOM   3773  N  N   . ASP A 1 494 ? 226.142 204.756 220.242 1.00 86.14  ? 494 ASP A N   1 
ATOM   3774  C  CA  . ASP A 1 494 ? 226.930 203.629 219.745 1.00 86.14  ? 494 ASP A CA  1 
ATOM   3775  C  C   . ASP A 1 494 ? 226.315 202.274 220.087 1.00 86.14  ? 494 ASP A C   1 
ATOM   3776  O  O   . ASP A 1 494 ? 226.920 201.247 219.761 1.00 86.14  ? 494 ASP A O   1 
ATOM   3777  C  CB  . ASP A 1 494 ? 228.381 203.647 220.252 1.00 86.14  ? 494 ASP A CB  1 
ATOM   3778  C  CG  . ASP A 1 494 ? 229.059 204.985 220.030 1.00 86.14  ? 494 ASP A CG  1 
ATOM   3779  O  OD1 . ASP A 1 494 ? 228.588 205.757 219.169 1.00 86.14  ? 494 ASP A OD1 1 
ATOM   3780  O  OD2 . ASP A 1 494 ? 230.064 205.263 220.718 1.00 86.14  ? 494 ASP A OD2 1 
ATOM   3781  N  N   . LYS A 1 495 ? 225.146 202.225 220.718 1.00 78.96  ? 495 LYS A N   1 
ATOM   3782  C  CA  . LYS A 1 495 ? 224.545 200.954 221.091 1.00 78.96  ? 495 LYS A CA  1 
ATOM   3783  C  C   . LYS A 1 495 ? 223.648 200.458 219.967 1.00 78.96  ? 495 LYS A C   1 
ATOM   3784  O  O   . LYS A 1 495 ? 222.710 201.167 219.582 1.00 78.96  ? 495 LYS A O   1 
ATOM   3785  C  CB  . LYS A 1 495 ? 223.748 201.094 222.373 1.00 78.96  ? 495 LYS A CB  1 
ATOM   3786  C  CG  . LYS A 1 495 ? 224.609 201.282 223.610 1.00 78.96  ? 495 LYS A CG  1 
ATOM   3787  C  CD  . LYS A 1 495 ? 223.768 201.297 224.874 1.00 78.96  ? 495 LYS A CD  1 
ATOM   3788  C  CE  . LYS A 1 495 ? 223.022 202.611 225.022 1.00 78.96  ? 495 LYS A CE  1 
ATOM   3789  N  NZ  . LYS A 1 495 ? 223.952 203.741 225.297 1.00 78.96  ? 495 LYS A NZ  1 
ATOM   3790  N  N   . PRO A 1 496 ? 223.895 199.270 219.412 1.00 78.38  ? 496 PRO A N   1 
ATOM   3791  C  CA  . PRO A 1 496 ? 223.071 198.765 218.303 1.00 78.38  ? 496 PRO A CA  1 
ATOM   3792  C  C   . PRO A 1 496 ? 221.816 198.077 218.822 1.00 78.38  ? 496 PRO A C   1 
ATOM   3793  O  O   . PRO A 1 496 ? 221.848 197.388 219.843 1.00 78.38  ? 496 PRO A O   1 
ATOM   3794  C  CB  . PRO A 1 496 ? 224.004 197.775 217.598 1.00 78.38  ? 496 PRO A CB  1 
ATOM   3795  C  CG  . PRO A 1 496 ? 224.874 197.260 218.699 1.00 78.38  ? 496 PRO A CG  1 
ATOM   3796  C  CD  . PRO A 1 496 ? 225.028 198.377 219.710 1.00 78.38  ? 496 PRO A CD  1 
ATOM   3797  N  N   . PHE A 1 497 ? 220.710 198.270 218.115 1.00 76.81  ? 497 PHE A N   1 
ATOM   3798  C  CA  . PHE A 1 497 ? 219.441 197.624 218.445 1.00 76.81  ? 497 PHE A CA  1 
ATOM   3799  C  C   . PHE A 1 497 ? 218.806 197.094 217.172 1.00 76.81  ? 497 PHE A C   1 
ATOM   3800  O  O   . PHE A 1 497 ? 218.432 197.892 216.293 1.00 76.81  ? 497 PHE A O   1 
ATOM   3801  C  CB  . PHE A 1 497 ? 218.499 198.602 219.146 1.00 76.81  ? 497 PHE A CB  1 
ATOM   3802  C  CG  . PHE A 1 497 ? 219.073 199.204 220.397 1.00 76.81  ? 497 PHE A CG  1 
ATOM   3803  C  CD1 . PHE A 1 497 ? 218.945 198.557 221.615 1.00 76.81  ? 497 PHE A CD1 1 
ATOM   3804  C  CD2 . PHE A 1 497 ? 219.742 200.417 220.356 1.00 76.81  ? 497 PHE A CD2 1 
ATOM   3805  C  CE1 . PHE A 1 497 ? 219.473 199.108 222.768 1.00 76.81  ? 497 PHE A CE1 1 
ATOM   3806  C  CE2 . PHE A 1 497 ? 220.273 200.972 221.506 1.00 76.81  ? 497 PHE A CE2 1 
ATOM   3807  C  CZ  . PHE A 1 497 ? 220.138 200.317 222.713 1.00 76.81  ? 497 PHE A CZ  1 
ATOM   3808  N  N   . PRO A 1 498 ? 218.665 195.785 217.016 1.00 68.15  ? 498 PRO A N   1 
ATOM   3809  C  CA  . PRO A 1 498 ? 218.102 195.205 215.776 1.00 68.15  ? 498 PRO A CA  1 
ATOM   3810  C  C   . PRO A 1 498 ? 216.575 195.146 215.733 1.00 68.15  ? 498 PRO A C   1 
ATOM   3811  O  O   . PRO A 1 498 ? 215.940 194.114 215.950 1.00 68.15  ? 498 PRO A O   1 
ATOM   3812  C  CB  . PRO A 1 498 ? 218.713 193.804 215.761 1.00 68.15  ? 498 PRO A CB  1 
ATOM   3813  C  CG  . PRO A 1 498 ? 218.852 193.460 217.206 1.00 68.15  ? 498 PRO A CG  1 
ATOM   3814  C  CD  . PRO A 1 498 ? 219.157 194.747 217.935 1.00 68.15  ? 498 PRO A CD  1 
ATOM   3815  N  N   . LEU A 1 499 ? 215.964 196.288 215.428 1.00 64.08  ? 499 LEU A N   1 
ATOM   3816  C  CA  . LEU A 1 499 ? 214.520 196.357 215.277 1.00 64.08  ? 499 LEU A CA  1 
ATOM   3817  C  C   . LEU A 1 499 ? 214.070 195.544 214.069 1.00 64.08  ? 499 LEU A C   1 
ATOM   3818  O  O   . LEU A 1 499 ? 214.810 195.347 213.106 1.00 64.08  ? 499 LEU A O   1 
ATOM   3819  C  CB  . LEU A 1 499 ? 214.062 197.803 215.120 1.00 64.08  ? 499 LEU A CB  1 
ATOM   3820  C  CG  . LEU A 1 499 ? 214.514 198.794 216.187 1.00 64.08  ? 499 LEU A CG  1 
ATOM   3821  C  CD1 . LEU A 1 499 ? 215.760 199.523 215.749 1.00 64.08  ? 499 LEU A CD1 1 
ATOM   3822  C  CD2 . LEU A 1 499 ? 213.405 199.780 216.484 1.00 64.08  ? 499 LEU A CD2 1 
ATOM   3823  N  N   . THR A 1 500 ? 212.833 195.062 214.128 1.00 61.48  ? 500 THR A N   1 
ATOM   3824  C  CA  . THR A 1 500 ? 212.273 194.312 213.014 1.00 61.48  ? 500 THR A CA  1 
ATOM   3825  C  C   . THR A 1 500 ? 210.898 194.874 212.681 1.00 61.48  ? 500 THR A C   1 
ATOM   3826  O  O   . THR A 1 500 ? 210.333 195.680 213.429 1.00 61.48  ? 500 THR A O   1 
ATOM   3827  C  CB  . THR A 1 500 ? 212.202 192.811 213.315 1.00 61.48  ? 500 THR A CB  1 
ATOM   3828  O  OG1 . THR A 1 500 ? 211.587 192.604 214.593 1.00 61.48  ? 500 THR A OG1 1 
ATOM   3829  C  CG2 . THR A 1 500 ? 213.587 192.202 213.311 1.00 61.48  ? 500 THR A CG2 1 
ATOM   3830  N  N   . LEU A 1 501 ? 210.359 194.442 211.545 1.00 54.99  ? 501 LEU A N   1 
ATOM   3831  C  CA  . LEU A 1 501 ? 209.109 194.974 211.034 1.00 54.99  ? 501 LEU A CA  1 
ATOM   3832  C  C   . LEU A 1 501 ? 208.197 193.843 210.587 1.00 54.99  ? 501 LEU A C   1 
ATOM   3833  O  O   . LEU A 1 501 ? 208.651 192.837 210.029 1.00 54.99  ? 501 LEU A O   1 
ATOM   3834  C  CB  . LEU A 1 501 ? 209.357 195.936 209.866 1.00 54.99  ? 501 LEU A CB  1 
ATOM   3835  C  CG  . LEU A 1 501 ? 210.432 197.017 210.021 1.00 54.99  ? 501 LEU A CG  1 
ATOM   3836  C  CD1 . LEU A 1 501 ? 210.486 197.865 208.768 1.00 54.99  ? 501 LEU A CD1 1 
ATOM   3837  C  CD2 . LEU A 1 501 ? 210.176 197.898 211.222 1.00 54.99  ? 501 LEU A CD2 1 
ATOM   3838  N  N   . SER A 1 502 ? 206.908 194.018 210.847 1.00 52.97  ? 502 SER A N   1 
ATOM   3839  C  CA  . SER A 1 502 ? 205.873 193.122 210.358 1.00 52.97  ? 502 SER A CA  1 
ATOM   3840  C  C   . SER A 1 502 ? 204.955 193.881 209.414 1.00 52.97  ? 502 SER A C   1 
ATOM   3841  O  O   . SER A 1 502 ? 204.536 195.000 209.705 1.00 52.97  ? 502 SER A O   1 
ATOM   3842  C  CB  . SER A 1 502 ? 205.056 192.537 211.511 1.00 52.97  ? 502 SER A CB  1 
ATOM   3843  O  OG  . SER A 1 502 ? 203.843 191.977 211.040 1.00 52.97  ? 502 SER A OG  1 
ATOM   3844  N  N   . ILE A 1 503 ? 204.640 193.281 208.274 1.00 47.24  ? 503 ILE A N   1 
ATOM   3845  C  CA  . ILE A 1 503 ? 203.853 193.980 207.262 1.00 47.24  ? 503 ILE A CA  1 
ATOM   3846  C  C   . ILE A 1 503 ? 202.679 193.110 206.843 1.00 47.24  ? 503 ILE A C   1 
ATOM   3847  O  O   . ILE A 1 503 ? 202.840 191.909 206.612 1.00 47.24  ? 503 ILE A O   1 
ATOM   3848  C  CB  . ILE A 1 503 ? 204.703 194.367 206.035 1.00 47.24  ? 503 ILE A CB  1 
ATOM   3849  C  CG1 . ILE A 1 503 ? 205.960 195.130 206.459 1.00 47.24  ? 503 ILE A CG1 1 
ATOM   3850  C  CG2 . ILE A 1 503 ? 203.883 195.183 205.050 1.00 47.24  ? 503 ILE A CG2 1 
ATOM   3851  C  CD1 . ILE A 1 503 ? 207.215 194.284 206.478 1.00 47.24  ? 503 ILE A CD1 1 
ATOM   3852  N  N   . GLY A 1 504 ? 201.505 193.707 206.750 1.00 42.35  ? 504 GLY A N   1 
ATOM   3853  C  CA  . GLY A 1 504 ? 200.319 193.017 206.275 1.00 42.35  ? 504 GLY A CA  1 
ATOM   3854  C  C   . GLY A 1 504 ? 199.723 193.775 205.108 1.00 42.35  ? 504 GLY A C   1 
ATOM   3855  O  O   . GLY A 1 504 ? 199.705 195.008 205.111 1.00 42.35  ? 504 GLY A O   1 
ATOM   3856  N  N   . ILE A 1 505 ? 199.241 193.034 204.113 1.00 47.76  ? 505 ILE A N   1 
ATOM   3857  C  CA  . ILE A 1 505 ? 198.746 193.607 202.865 1.00 47.76  ? 505 ILE A CA  1 
ATOM   3858  C  C   . ILE A 1 505 ? 197.278 193.244 202.694 1.00 47.76  ? 505 ILE A C   1 
ATOM   3859  O  O   . ILE A 1 505 ? 196.879 192.107 202.964 1.00 47.76  ? 505 ILE A O   1 
ATOM   3860  C  CB  . ILE A 1 505 ? 199.561 193.122 201.645 1.00 47.76  ? 505 ILE A CB  1 
ATOM   3861  C  CG1 . ILE A 1 505 ? 201.011 193.588 201.728 1.00 47.76  ? 505 ILE A CG1 1 
ATOM   3862  C  CG2 . ILE A 1 505 ? 198.958 193.638 200.363 1.00 47.76  ? 505 ILE A CG2 1 
ATOM   3863  C  CD1 . ILE A 1 505 ? 201.973 192.517 202.167 1.00 47.76  ? 505 ILE A CD1 1 
ATOM   3864  N  N   . SER A 1 506 ? 196.475 194.208 202.241 1.00 48.61  ? 506 SER A N   1 
ATOM   3865  C  CA  . SER A 1 506 ? 195.067 193.973 201.962 1.00 48.61  ? 506 SER A CA  1 
ATOM   3866  C  C   . SER A 1 506 ? 194.691 194.532 200.599 1.00 48.61  ? 506 SER A C   1 
ATOM   3867  O  O   . SER A 1 506 ? 195.094 195.633 200.230 1.00 48.61  ? 506 SER A O   1 
ATOM   3868  C  CB  . SER A 1 506 ? 194.173 194.600 203.031 1.00 48.61  ? 506 SER A CB  1 
ATOM   3869  O  OG  . SER A 1 506 ? 192.816 194.261 202.807 1.00 48.61  ? 506 SER A OG  1 
ATOM   3870  N  N   . TYR A 1 507 ? 193.861 193.780 199.877 1.00 53.56  ? 507 TYR A N   1 
ATOM   3871  C  CA  . TYR A 1 507 ? 193.371 194.144 198.551 1.00 53.56  ? 507 TYR A CA  1 
ATOM   3872  C  C   . TYR A 1 507 ? 191.893 193.830 198.450 1.00 53.56  ? 507 TYR A C   1 
ATOM   3873  O  O   . TYR A 1 507 ? 191.366 192.996 199.189 1.00 53.56  ? 507 TYR A O   1 
ATOM   3874  C  CB  . TYR A 1 507 ? 194.098 193.393 197.427 1.00 53.56  ? 507 TYR A CB  1 
ATOM   3875  C  CG  . TYR A 1 507 ? 195.489 193.867 197.171 1.00 53.56  ? 507 TYR A CG  1 
ATOM   3876  C  CD1 . TYR A 1 507 ? 195.873 195.115 197.571 1.00 53.56  ? 507 TYR A CD1 1 
ATOM   3877  C  CD2 . TYR A 1 507 ? 196.438 193.038 196.595 1.00 53.56  ? 507 TYR A CD2 1 
ATOM   3878  C  CE1 . TYR A 1 507 ? 197.127 195.559 197.378 1.00 53.56  ? 507 TYR A CE1 1 
ATOM   3879  C  CE2 . TYR A 1 507 ? 197.730 193.480 196.398 1.00 53.56  ? 507 TYR A CE2 1 
ATOM   3880  C  CZ  . TYR A 1 507 ? 198.061 194.753 196.799 1.00 53.56  ? 507 TYR A CZ  1 
ATOM   3881  O  OH  . TYR A 1 507 ? 199.322 195.265 196.638 1.00 53.56  ? 507 TYR A OH  1 
ATOM   3882  N  N   . ASP A 1 508 ? 191.241 194.510 197.516 1.00 61.02  ? 508 ASP A N   1 
ATOM   3883  C  CA  . ASP A 1 508 ? 189.901 194.194 197.052 1.00 61.02  ? 508 ASP A CA  1 
ATOM   3884  C  C   . ASP A 1 508 ? 189.611 195.150 195.907 1.00 61.02  ? 508 ASP A C   1 
ATOM   3885  O  O   . ASP A 1 508 ? 190.438 195.996 195.558 1.00 61.02  ? 508 ASP A O   1 
ATOM   3886  C  CB  . ASP A 1 508 ? 188.841 194.325 198.141 1.00 61.02  ? 508 ASP A CB  1 
ATOM   3887  C  CG  . ASP A 1 508 ? 187.656 193.415 197.904 1.00 61.02  ? 508 ASP A CG  1 
ATOM   3888  O  OD1 . ASP A 1 508 ? 187.716 192.601 196.959 1.00 61.02  ? 508 ASP A OD1 1 
ATOM   3889  O  OD2 . ASP A 1 508 ? 186.666 193.516 198.657 1.00 61.02  ? 508 ASP A OD2 1 
ATOM   3890  N  N   . LEU A 1 509 ? 188.425 195.010 195.325 1.00 64.49  ? 509 LEU A N   1 
ATOM   3891  C  CA  . LEU A 1 509 ? 187.966 196.017 194.380 1.00 64.49  ? 509 LEU A CA  1 
ATOM   3892  C  C   . LEU A 1 509 ? 187.395 197.242 195.079 1.00 64.49  ? 509 LEU A C   1 
ATOM   3893  O  O   . LEU A 1 509 ? 186.701 198.038 194.437 1.00 64.49  ? 509 LEU A O   1 
ATOM   3894  C  CB  . LEU A 1 509 ? 186.926 195.422 193.423 1.00 64.49  ? 509 LEU A CB  1 
ATOM   3895  C  CG  . LEU A 1 509 ? 185.511 195.105 193.920 1.00 64.49  ? 509 LEU A CG  1 
ATOM   3896  C  CD1 . LEU A 1 509 ? 184.571 194.922 192.738 1.00 64.49  ? 509 LEU A CD1 1 
ATOM   3897  C  CD2 . LEU A 1 509 ? 185.489 193.864 194.800 1.00 64.49  ? 509 LEU A CD2 1 
ATOM   3898  N  N   . GLY A 1 510 ? 187.683 197.411 196.367 1.00 61.05  ? 510 GLY A N   1 
ATOM   3899  C  CA  . GLY A 1 510 ? 187.097 198.467 197.164 1.00 61.05  ? 510 GLY A CA  1 
ATOM   3900  C  C   . GLY A 1 510 ? 186.370 197.894 198.361 1.00 61.05  ? 510 GLY A C   1 
ATOM   3901  O  O   . GLY A 1 510 ? 185.487 197.047 198.206 1.00 61.05  ? 510 GLY A O   1 
ATOM   3902  N  N   . LYS A 1 511 ? 186.731 198.337 199.559 1.00 61.53  ? 511 LYS A N   1 
ATOM   3903  C  CA  . LYS A 1 511 ? 186.134 197.782 200.764 1.00 61.53  ? 511 LYS A CA  1 
ATOM   3904  C  C   . LYS A 1 511 ? 186.126 198.869 201.828 1.00 61.53  ? 511 LYS A C   1 
ATOM   3905  O  O   . LYS A 1 511 ? 186.598 199.985 201.597 1.00 61.53  ? 511 LYS A O   1 
ATOM   3906  C  CB  . LYS A 1 511 ? 186.886 196.530 201.233 1.00 61.53  ? 511 LYS A CB  1 
ATOM   3907  C  CG  . LYS A 1 511 ? 186.066 195.568 202.083 1.00 61.53  ? 511 LYS A CG  1 
ATOM   3908  C  CD  . LYS A 1 511 ? 186.479 194.120 201.853 1.00 61.53  ? 511 LYS A CD  1 
ATOM   3909  C  CE  . LYS A 1 511 ? 187.941 193.900 202.187 1.00 61.53  ? 511 LYS A CE  1 
ATOM   3910  N  NZ  . LYS A 1 511 ? 188.263 192.460 202.290 1.00 61.53  ? 511 LYS A NZ  1 
ATOM   3911  N  N   . ASN A 1 512 ? 185.574 198.535 202.990 1.00 64.79  ? 512 ASN A N   1 
ATOM   3912  C  CA  . ASN A 1 512 ? 185.271 199.546 203.992 1.00 64.79  ? 512 ASN A CA  1 
ATOM   3913  C  C   . ASN A 1 512 ? 186.540 200.215 204.516 1.00 64.79  ? 512 ASN A C   1 
ATOM   3914  O  O   . ASN A 1 512 ? 187.611 199.606 204.604 1.00 64.79  ? 512 ASN A O   1 
ATOM   3915  C  CB  . ASN A 1 512 ? 184.480 198.929 205.144 1.00 64.79  ? 512 ASN A CB  1 
ATOM   3916  C  CG  . ASN A 1 512 ? 183.025 198.693 204.786 1.00 64.79  ? 512 ASN A CG  1 
ATOM   3917  O  OD1 . ASN A 1 512 ? 182.429 199.458 204.027 1.00 64.79  ? 512 ASN A OD1 1 
ATOM   3918  N  ND2 . ASN A 1 512 ? 182.445 197.630 205.331 1.00 64.79  ? 512 ASN A ND2 1 
ATOM   3919  N  N   . ARG A 1 513 ? 186.389 201.492 204.870 1.00 61.10  ? 513 ARG A N   1 
ATOM   3920  C  CA  . ARG A 1 513 ? 187.525 202.358 205.168 1.00 61.10  ? 513 ARG A CA  1 
ATOM   3921  C  C   . ARG A 1 513 ? 188.287 201.886 206.399 1.00 61.10  ? 513 ARG A C   1 
ATOM   3922  O  O   . ARG A 1 513 ? 189.519 201.949 206.441 1.00 61.10  ? 513 ARG A O   1 
ATOM   3923  C  CB  . ARG A 1 513 ? 187.018 203.788 205.349 1.00 61.10  ? 513 ARG A CB  1 
ATOM   3924  C  CG  . ARG A 1 513 ? 187.986 204.756 205.985 1.00 61.10  ? 513 ARG A CG  1 
ATOM   3925  C  CD  . ARG A 1 513 ? 187.248 206.019 206.397 1.00 61.10  ? 513 ARG A CD  1 
ATOM   3926  N  NE  . ARG A 1 513 ? 186.188 205.737 207.357 1.00 61.10  ? 513 ARG A NE  1 
ATOM   3927  C  CZ  . ARG A 1 513 ? 185.136 206.517 207.564 1.00 61.10  ? 513 ARG A CZ  1 
ATOM   3928  N  NH1 . ARG A 1 513 ? 184.971 207.647 206.896 1.00 61.10  ? 513 ARG A NH1 1 
ATOM   3929  N  NH2 . ARG A 1 513 ? 184.228 206.155 208.465 1.00 61.10  ? 513 ARG A NH2 1 
ATOM   3930  N  N   . ASP A 1 514 ? 187.567 201.440 207.426 1.00 66.36  ? 514 ASP A N   1 
ATOM   3931  C  CA  . ASP A 1 514 ? 188.199 200.866 208.607 1.00 66.36  ? 514 ASP A CA  1 
ATOM   3932  C  C   . ASP A 1 514 ? 188.453 199.372 208.463 1.00 66.36  ? 514 ASP A C   1 
ATOM   3933  O  O   . ASP A 1 514 ? 189.258 198.806 209.219 1.00 66.36  ? 514 ASP A O   1 
ATOM   3934  C  CB  . ASP A 1 514 ? 187.331 201.120 209.844 1.00 66.36  ? 514 ASP A CB  1 
ATOM   3935  C  CG  . ASP A 1 514 ? 188.148 201.240 211.114 1.00 66.36  ? 514 ASP A CG  1 
ATOM   3936  O  OD1 . ASP A 1 514 ? 189.183 201.938 211.095 1.00 66.36  ? 514 ASP A OD1 1 
ATOM   3937  O  OD2 . ASP A 1 514 ? 187.753 200.638 212.134 1.00 66.36  ? 514 ASP A OD2 1 
ATOM   3938  N  N   . TYR A 1 515 ? 187.789 198.724 207.508 1.00 64.15  ? 515 TYR A N   1 
ATOM   3939  C  CA  . TYR A 1 515 ? 188.025 197.309 207.275 1.00 64.15  ? 515 TYR A CA  1 
ATOM   3940  C  C   . TYR A 1 515 ? 189.374 197.085 206.607 1.00 64.15  ? 515 TYR A C   1 
ATOM   3941  O  O   . TYR A 1 515 ? 190.044 196.092 206.900 1.00 64.15  ? 515 TYR A O   1 
ATOM   3942  C  CB  . TYR A 1 515 ? 186.876 196.735 206.446 1.00 64.15  ? 515 TYR A CB  1 
ATOM   3943  C  CG  . TYR A 1 515 ? 186.750 195.231 206.465 1.00 64.15  ? 515 TYR A CG  1 
ATOM   3944  C  CD1 . TYR A 1 515 ? 186.338 194.565 207.612 1.00 64.15  ? 515 TYR A CD1 1 
ATOM   3945  C  CD2 . TYR A 1 515 ? 186.971 194.482 205.323 1.00 64.15  ? 515 TYR A CD2 1 
ATOM   3946  C  CE1 . TYR A 1 515 ? 186.201 193.187 207.631 1.00 64.15  ? 515 TYR A CE1 1 
ATOM   3947  C  CE2 . TYR A 1 515 ? 186.827 193.105 205.327 1.00 64.15  ? 515 TYR A CE2 1 
ATOM   3948  C  CZ  . TYR A 1 515 ? 186.447 192.464 206.484 1.00 64.15  ? 515 TYR A CZ  1 
ATOM   3949  O  OH  . TYR A 1 515 ? 186.308 191.094 206.491 1.00 64.15  ? 515 TYR A OH  1 
ATOM   3950  N  N   . LEU A 1 516 ? 189.807 198.007 205.742 1.00 55.07  ? 516 LEU A N   1 
ATOM   3951  C  CA  . LEU A 1 516 ? 191.171 197.942 205.222 1.00 55.07  ? 516 LEU A CA  1 
ATOM   3952  C  C   . LEU A 1 516 ? 192.224 198.217 206.281 1.00 55.07  ? 516 LEU A C   1 
ATOM   3953  O  O   . LEU A 1 516 ? 193.410 198.246 205.946 1.00 55.07  ? 516 LEU A O   1 
ATOM   3954  C  CB  . LEU A 1 516 ? 191.378 198.917 204.065 1.00 55.07  ? 516 LEU A CB  1 
ATOM   3955  C  CG  . LEU A 1 516 ? 191.086 198.425 202.650 1.00 55.07  ? 516 LEU A CG  1 
ATOM   3956  C  CD1 . LEU A 1 516 ? 189.601 198.397 202.387 1.00 55.07  ? 516 LEU A CD1 1 
ATOM   3957  C  CD2 . LEU A 1 516 ? 191.800 199.286 201.630 1.00 55.07  ? 516 LEU A CD2 1 
ATOM   3958  N  N   . LEU A 1 517 ? 191.835 198.449 207.528 1.00 58.21  ? 517 LEU A N   1 
ATOM   3959  C  CA  . LEU A 1 517 ? 192.766 198.456 208.647 1.00 58.21  ? 517 LEU A CA  1 
ATOM   3960  C  C   . LEU A 1 517 ? 192.610 197.239 209.539 1.00 58.21  ? 517 LEU A C   1 
ATOM   3961  O  O   . LEU A 1 517 ? 193.607 196.682 209.997 1.00 58.21  ? 517 LEU A O   1 
ATOM   3962  C  CB  . LEU A 1 517 ? 192.584 199.722 209.490 1.00 58.21  ? 517 LEU A CB  1 
ATOM   3963  C  CG  . LEU A 1 517 ? 193.237 201.016 209.002 1.00 58.21  ? 517 LEU A CG  1 
ATOM   3964  C  CD1 . LEU A 1 517 ? 192.532 201.562 207.772 1.00 58.21  ? 517 LEU A CD1 1 
ATOM   3965  C  CD2 . LEU A 1 517 ? 193.251 202.049 210.116 1.00 58.21  ? 517 LEU A CD2 1 
ATOM   3966  N  N   . SER A 1 518 ? 191.373 196.806 209.785 1.00 60.58  ? 518 SER A N   1 
ATOM   3967  C  CA  . SER A 1 518 ? 191.155 195.599 210.581 1.00 60.58  ? 518 SER A CA  1 
ATOM   3968  C  C   . SER A 1 518 ? 191.731 194.364 209.888 1.00 60.58  ? 518 SER A C   1 
ATOM   3969  O  O   . SER A 1 518 ? 192.388 193.523 210.521 1.00 60.58  ? 518 SER A O   1 
ATOM   3970  C  CB  . SER A 1 518 ? 189.662 195.417 210.857 1.00 60.58  ? 518 SER A CB  1 
ATOM   3971  O  OG  . SER A 1 518 ? 189.433 194.328 211.733 1.00 60.58  ? 518 SER A OG  1 
ATOM   3972  N  N   . THR A 1 519 ? 191.493 194.235 208.583 1.00 55.37  ? 519 THR A N   1 
ATOM   3973  C  CA  . THR A 1 519 ? 192.035 193.108 207.836 1.00 55.37  ? 519 THR A CA  1 
ATOM   3974  C  C   . THR A 1 519 ? 193.557 193.138 207.841 1.00 55.37  ? 519 THR A C   1 
ATOM   3975  O  O   . THR A 1 519 ? 194.213 192.106 208.009 1.00 55.37  ? 519 THR A O   1 
ATOM   3976  C  CB  . THR A 1 519 ? 191.495 193.122 206.411 1.00 55.37  ? 519 THR A CB  1 
ATOM   3977  O  OG1 . THR A 1 519 ? 191.784 194.384 205.802 1.00 55.37  ? 519 THR A OG1 1 
ATOM   3978  C  CG2 . THR A 1 519 ? 190.018 192.912 206.421 1.00 55.37  ? 519 THR A CG2 1 
ATOM   3979  N  N   . ALA A 1 520 ? 194.136 194.322 207.674 1.00 53.76  ? 520 ALA A N   1 
ATOM   3980  C  CA  . ALA A 1 520 ? 195.582 194.469 207.726 1.00 53.76  ? 520 ALA A CA  1 
ATOM   3981  C  C   . ALA A 1 520 ? 196.103 194.060 209.095 1.00 53.76  ? 520 ALA A C   1 
ATOM   3982  O  O   . ALA A 1 520 ? 197.178 193.460 209.210 1.00 53.76  ? 520 ALA A O   1 
ATOM   3983  C  CB  . ALA A 1 520 ? 195.982 195.907 207.408 1.00 53.76  ? 520 ALA A CB  1 
ATOM   3984  N  N   . HIS A 1 521 ? 195.345 194.377 210.143 1.00 53.90  ? 521 HIS A N   1 
ATOM   3985  C  CA  . HIS A 1 521 ? 195.780 194.009 211.481 1.00 53.90  ? 521 HIS A CA  1 
ATOM   3986  C  C   . HIS A 1 521 ? 195.685 192.512 211.724 1.00 53.90  ? 521 HIS A C   1 
ATOM   3987  O  O   . HIS A 1 521 ? 196.442 191.993 212.545 1.00 53.90  ? 521 HIS A O   1 
ATOM   3988  C  CB  . HIS A 1 521 ? 194.984 194.775 212.530 1.00 53.90  ? 521 HIS A CB  1 
ATOM   3989  C  CG  . HIS A 1 521 ? 195.797 195.158 213.724 1.00 53.90  ? 521 HIS A CG  1 
ATOM   3990  N  ND1 . HIS A 1 521 ? 195.873 194.380 214.857 1.00 53.90  ? 521 HIS A ND1 1 
ATOM   3991  C  CD2 . HIS A 1 521 ? 196.593 196.228 213.949 1.00 53.90  ? 521 HIS A CD2 1 
ATOM   3992  C  CE1 . HIS A 1 521 ? 196.669 194.963 215.735 1.00 53.90  ? 521 HIS A CE1 1 
ATOM   3993  N  NE2 . HIS A 1 521 ? 197.118 196.087 215.209 1.00 53.90  ? 521 HIS A NE2 1 
ATOM   3994  N  N   . ASN A 1 522 ? 194.785 191.807 211.031 1.00 56.27  ? 522 ASN A N   1 
ATOM   3995  C  CA  . ASN A 1 522 ? 194.838 190.341 211.065 1.00 56.27  ? 522 ASN A CA  1 
ATOM   3996  C  C   . ASN A 1 522 ? 196.214 189.834 210.654 1.00 56.27  ? 522 ASN A C   1 
ATOM   3997  O  O   . ASN A 1 522 ? 196.844 189.050 211.377 1.00 56.27  ? 522 ASN A O   1 
ATOM   3998  C  CB  . ASN A 1 522 ? 193.772 189.721 210.159 1.00 56.27  ? 522 ASN A CB  1 
ATOM   3999  C  CG  . ASN A 1 522 ? 192.441 189.556 210.851 1.00 56.27  ? 522 ASN A CG  1 
ATOM   4000  O  OD1 . ASN A 1 522 ? 192.378 189.121 211.999 1.00 56.27  ? 522 ASN A OD1 1 
ATOM   4001  N  ND2 . ASN A 1 522 ? 191.364 189.895 210.154 1.00 56.27  ? 522 ASN A ND2 1 
ATOM   4002  N  N   . ALA A 1 523 ? 196.704 190.287 209.498 1.00 50.22  ? 523 ALA A N   1 
ATOM   4003  C  CA  . ALA A 1 523 ? 198.009 189.844 209.022 1.00 50.22  ? 523 ALA A CA  1 
ATOM   4004  C  C   . ALA A 1 523 ? 199.123 190.301 209.951 1.00 50.22  ? 523 ALA A C   1 
ATOM   4005  O  O   . ALA A 1 523 ? 200.061 189.542 210.232 1.00 50.22  ? 523 ALA A O   1 
ATOM   4006  C  CB  . ALA A 1 523 ? 198.247 190.356 207.605 1.00 50.22  ? 523 ALA A CB  1 
ATOM   4007  N  N   . MET A 1 524 ? 199.043 191.539 210.436 1.00 52.20  ? 524 MET A N   1 
ATOM   4008  C  CA  . MET A 1 524 ? 200.090 192.037 211.318 1.00 52.20  ? 524 MET A CA  1 
ATOM   4009  C  C   . MET A 1 524 ? 200.162 191.217 212.597 1.00 52.20  ? 524 MET A C   1 
ATOM   4010  O  O   . MET A 1 524 ? 201.251 190.850 213.047 1.00 52.20  ? 524 MET A O   1 
ATOM   4011  C  CB  . MET A 1 524 ? 199.860 193.506 211.644 1.00 52.20  ? 524 MET A CB  1 
ATOM   4012  C  CG  . MET A 1 524 ? 201.113 194.206 212.138 1.00 52.20  ? 524 MET A CG  1 
ATOM   4013  S  SD  . MET A 1 524 ? 201.500 193.921 213.870 1.00 52.20  ? 524 MET A SD  1 
ATOM   4014  C  CE  . MET A 1 524 ? 200.261 194.938 214.664 1.00 52.20  ? 524 MET A CE  1 
ATOM   4015  N  N   . ASP A 1 525 ? 199.008 190.927 213.205 1.00 57.63  ? 525 ASP A N   1 
ATOM   4016  C  CA  . ASP A 1 525 ? 198.990 190.142 214.432 1.00 57.63  ? 525 ASP A CA  1 
ATOM   4017  C  C   . ASP A 1 525 ? 199.489 188.726 214.185 1.00 57.63  ? 525 ASP A C   1 
ATOM   4018  O  O   . ASP A 1 525 ? 200.248 188.178 214.995 1.00 57.63  ? 525 ASP A O   1 
ATOM   4019  C  CB  . ASP A 1 525 ? 197.580 190.122 215.015 1.00 57.63  ? 525 ASP A CB  1 
ATOM   4020  C  CG  . ASP A 1 525 ? 197.508 189.386 216.335 1.00 57.63  ? 525 ASP A CG  1 
ATOM   4021  O  OD1 . ASP A 1 525 ? 198.328 189.684 217.228 1.00 57.63  ? 525 ASP A OD1 1 
ATOM   4022  O  OD2 . ASP A 1 525 ? 196.633 188.507 216.480 1.00 57.63  ? 525 ASP A OD2 1 
ATOM   4023  N  N   . TYR A 1 526 ? 199.077 188.120 213.068 1.00 55.76  ? 526 TYR A N   1 
ATOM   4024  C  CA  . TYR A 1 526 ? 199.567 186.794 212.711 1.00 55.76  ? 526 TYR A CA  1 
ATOM   4025  C  C   . TYR A 1 526 ? 201.088 186.772 212.667 1.00 55.76  ? 526 TYR A C   1 
ATOM   4026  O  O   . TYR A 1 526 ? 201.733 185.943 213.322 1.00 55.76  ? 526 TYR A O   1 
ATOM   4027  C  CB  . TYR A 1 526 ? 198.980 186.393 211.357 1.00 55.76  ? 526 TYR A CB  1 
ATOM   4028  C  CG  . TYR A 1 526 ? 199.221 184.965 210.930 1.00 55.76  ? 526 TYR A CG  1 
ATOM   4029  C  CD1 . TYR A 1 526 ? 200.479 184.537 210.531 1.00 55.76  ? 526 TYR A CD1 1 
ATOM   4030  C  CD2 . TYR A 1 526 ? 198.179 184.051 210.897 1.00 55.76  ? 526 TYR A CD2 1 
ATOM   4031  C  CE1 . TYR A 1 526 ? 200.696 183.236 210.133 1.00 55.76  ? 526 TYR A CE1 1 
ATOM   4032  C  CE2 . TYR A 1 526 ? 198.385 182.747 210.499 1.00 55.76  ? 526 TYR A CE2 1 
ATOM   4033  C  CZ  . TYR A 1 526 ? 199.646 182.344 210.118 1.00 55.76  ? 526 TYR A CZ  1 
ATOM   4034  O  OH  . TYR A 1 526 ? 199.857 181.044 209.720 1.00 55.76  ? 526 TYR A OH  1 
ATOM   4035  N  N   . ILE A 1 527 ? 201.679 187.698 211.912 1.00 55.55  ? 527 ILE A N   1 
ATOM   4036  C  CA  . ILE A 1 527 ? 203.130 187.697 211.772 1.00 55.55  ? 527 ILE A CA  1 
ATOM   4037  C  C   . ILE A 1 527 ? 203.799 188.004 213.105 1.00 55.55  ? 527 ILE A C   1 
ATOM   4038  O  O   . ILE A 1 527 ? 204.760 187.333 213.492 1.00 55.55  ? 527 ILE A O   1 
ATOM   4039  C  CB  . ILE A 1 527 ? 203.572 188.672 210.670 1.00 55.55  ? 527 ILE A CB  1 
ATOM   4040  C  CG1 . ILE A 1 527 ? 203.384 188.016 209.308 1.00 55.55  ? 527 ILE A CG1 1 
ATOM   4041  C  CG2 . ILE A 1 527 ? 205.023 189.046 210.850 1.00 55.55  ? 527 ILE A CG2 1 
ATOM   4042  C  CD1 . ILE A 1 527 ? 204.265 186.820 209.104 1.00 55.55  ? 527 ILE A CD1 1 
ATOM   4043  N  N   . ARG A 1 528 ? 203.290 188.992 213.844 1.00 58.38  ? 528 ARG A N   1 
ATOM   4044  C  CA  . ARG A 1 528 ? 203.922 189.361 215.104 1.00 58.38  ? 528 ARG A CA  1 
ATOM   4045  C  C   . ARG A 1 528 ? 203.919 188.199 216.086 1.00 58.38  ? 528 ARG A C   1 
ATOM   4046  O  O   . ARG A 1 528 ? 204.899 187.989 216.810 1.00 58.38  ? 528 ARG A O   1 
ATOM   4047  C  CB  . ARG A 1 528 ? 203.221 190.573 215.708 1.00 58.38  ? 528 ARG A CB  1 
ATOM   4048  C  CG  . ARG A 1 528 ? 203.729 190.964 217.077 1.00 58.38  ? 528 ARG A CG  1 
ATOM   4049  C  CD  . ARG A 1 528 ? 205.228 191.177 217.080 1.00 58.38  ? 528 ARG A CD  1 
ATOM   4050  N  NE  . ARG A 1 528 ? 205.636 192.091 218.139 1.00 58.38  ? 528 ARG A NE  1 
ATOM   4051  C  CZ  . ARG A 1 528 ? 206.727 191.943 218.877 1.00 58.38  ? 528 ARG A CZ  1 
ATOM   4052  N  NH1 . ARG A 1 528 ? 207.551 190.924 218.697 1.00 58.38  ? 528 ARG A NH1 1 
ATOM   4053  N  NH2 . ARG A 1 528 ? 207.000 192.842 219.818 1.00 58.38  ? 528 ARG A NH2 1 
ATOM   4054  N  N   . LYS A 1 529 ? 202.834 187.425 216.125 1.00 60.43  ? 529 LYS A N   1 
ATOM   4055  C  CA  . LYS A 1 529 ? 202.790 186.308 217.061 1.00 60.43  ? 529 LYS A CA  1 
ATOM   4056  C  C   . LYS A 1 529 ? 203.632 185.134 216.572 1.00 60.43  ? 529 LYS A C   1 
ATOM   4057  O  O   . LYS A 1 529 ? 204.166 184.374 217.386 1.00 60.43  ? 529 LYS A O   1 
ATOM   4058  C  CB  . LYS A 1 529 ? 201.344 185.874 217.309 1.00 60.43  ? 529 LYS A CB  1 
ATOM   4059  C  CG  . LYS A 1 529 ? 200.684 185.143 216.153 1.00 60.43  ? 529 LYS A CG  1 
ATOM   4060  C  CD  . LYS A 1 529 ? 199.234 184.812 216.463 1.00 60.43  ? 529 LYS A CD  1 
ATOM   4061  C  CE  . LYS A 1 529 ? 199.130 183.674 217.465 1.00 60.43  ? 529 LYS A CE  1 
ATOM   4062  N  NZ  . LYS A 1 529 ? 197.719 183.245 217.674 1.00 60.43  ? 529 LYS A NZ  1 
ATOM   4063  N  N   . ASN A 1 530 ? 203.776 184.970 215.257 1.00 59.43  ? 530 ASN A N   1 
ATOM   4064  C  CA  . ASN A 1 530 ? 204.458 183.799 214.725 1.00 59.43  ? 530 ASN A CA  1 
ATOM   4065  C  C   . ASN A 1 530 ? 205.871 184.093 214.217 1.00 59.43  ? 530 ASN A C   1 
ATOM   4066  O  O   . ASN A 1 530 ? 206.446 183.259 213.510 1.00 59.43  ? 530 ASN A O   1 
ATOM   4067  C  CB  . ASN A 1 530 ? 203.617 183.170 213.613 1.00 59.43  ? 530 ASN A CB  1 
ATOM   4068  C  CG  . ASN A 1 530 ? 202.274 182.672 214.113 1.00 59.43  ? 530 ASN A CG  1 
ATOM   4069  O  OD1 . ASN A 1 530 ? 202.142 182.268 215.267 1.00 59.43  ? 530 ASN A OD1 1 
ATOM   4070  N  ND2 . ASN A 1 530 ? 201.272 182.689 213.241 1.00 59.43  ? 530 ASN A ND2 1 
ATOM   4071  N  N   . GLY A 1 531 ? 206.444 185.245 214.560 1.00 59.59  ? 531 GLY A N   1 
ATOM   4072  C  CA  . GLY A 1 531 ? 207.796 185.568 214.132 1.00 59.59  ? 531 GLY A CA  1 
ATOM   4073  C  C   . GLY A 1 531 ? 208.026 187.044 213.869 1.00 59.59  ? 531 GLY A C   1 
ATOM   4074  O  O   . GLY A 1 531 ? 207.269 187.672 213.127 1.00 59.59  ? 531 GLY A O   1 
ATOM   4075  N  N   . GLY A 1 532 ? 209.103 187.595 214.431 1.00 63.12  ? 532 GLY A N   1 
ATOM   4076  C  CA  . GLY A 1 532 ? 209.215 189.043 214.538 1.00 63.12  ? 532 GLY A CA  1 
ATOM   4077  C  C   . GLY A 1 532 ? 209.208 189.768 213.204 1.00 63.12  ? 532 GLY A C   1 
ATOM   4078  O  O   . GLY A 1 532 ? 208.471 190.739 213.018 1.00 63.12  ? 532 GLY A O   1 
ATOM   4079  N  N   . ASN A 1 533 ? 210.022 189.311 212.257 1.00 58.26  ? 533 ASN A N   1 
ATOM   4080  C  CA  . ASN A 1 533 ? 210.288 190.052 211.028 1.00 58.26  ? 533 ASN A CA  1 
ATOM   4081  C  C   . ASN A 1 533 ? 209.681 189.324 209.837 1.00 58.26  ? 533 ASN A C   1 
ATOM   4082  O  O   . ASN A 1 533 ? 209.988 188.152 209.604 1.00 58.26  ? 533 ASN A O   1 
ATOM   4083  C  CB  . ASN A 1 533 ? 211.791 190.236 210.831 1.00 58.26  ? 533 ASN A CB  1 
ATOM   4084  C  CG  . ASN A 1 533 ? 212.118 191.232 209.741 1.00 58.26  ? 533 ASN A CG  1 
ATOM   4085  O  OD1 . ASN A 1 533 ? 211.226 191.831 209.141 1.00 58.26  ? 533 ASN A OD1 1 
ATOM   4086  N  ND2 . ASN A 1 533 ? 213.407 191.414 209.475 1.00 58.26  ? 533 ASN A ND2 1 
ATOM   4087  N  N   . GLY A 1 534 ? 208.838 190.018 209.079 1.00 52.53  ? 534 GLY A N   1 
ATOM   4088  C  CA  . GLY A 1 534 ? 208.257 189.404 207.896 1.00 52.53  ? 534 GLY A CA  1 
ATOM   4089  C  C   . GLY A 1 534 ? 207.008 190.142 207.437 1.00 52.53  ? 534 GLY A C   1 
ATOM   4090  O  O   . GLY A 1 534 ? 206.666 191.198 207.961 1.00 52.53  ? 534 GLY A O   1 
ATOM   4091  N  N   . TRP A 1 535 ? 206.342 189.554 206.446 1.00 46.89  ? 535 TRP A N   1 
ATOM   4092  C  CA  . TRP A 1 535 ? 205.167 190.184 205.862 1.00 46.89  ? 535 TRP A CA  1 
ATOM   4093  C  C   . TRP A 1 535 ? 204.284 189.126 205.217 1.00 46.89  ? 535 TRP A C   1 
ATOM   4094  O  O   . TRP A 1 535 ? 204.758 188.062 204.815 1.00 46.89  ? 535 TRP A O   1 
ATOM   4095  C  CB  . TRP A 1 535 ? 205.561 191.242 204.833 1.00 46.89  ? 535 TRP A CB  1 
ATOM   4096  C  CG  . TRP A 1 535 ? 206.431 190.738 203.749 1.00 46.89  ? 535 TRP A CG  1 
ATOM   4097  C  CD1 . TRP A 1 535 ? 207.787 190.792 203.701 1.00 46.89  ? 535 TRP A CD1 1 
ATOM   4098  C  CD2 . TRP A 1 535 ? 206.007 190.117 202.538 1.00 46.89  ? 535 TRP A CD2 1 
ATOM   4099  N  NE1 . TRP A 1 535 ? 208.238 190.233 202.533 1.00 46.89  ? 535 TRP A NE1 1 
ATOM   4100  C  CE2 . TRP A 1 535 ? 207.160 189.809 201.803 1.00 46.89  ? 535 TRP A CE2 1 
ATOM   4101  C  CE3 . TRP A 1 535 ? 204.765 189.779 202.008 1.00 46.89  ? 535 TRP A CE3 1 
ATOM   4102  C  CZ2 . TRP A 1 535 ? 207.106 189.182 200.564 1.00 46.89  ? 535 TRP A CZ2 1 
ATOM   4103  C  CZ3 . TRP A 1 535 ? 204.714 189.158 200.785 1.00 46.89  ? 535 TRP A CZ3 1 
ATOM   4104  C  CH2 . TRP A 1 535 ? 205.871 188.869 200.074 1.00 46.89  ? 535 TRP A CH2 1 
ATOM   4105  N  N   . GLN A 1 536 ? 202.996 189.446 205.108 1.00 50.66  ? 536 GLN A N   1 
ATOM   4106  C  CA  . GLN A 1 536 ? 202.018 188.529 204.544 1.00 50.66  ? 536 GLN A CA  1 
ATOM   4107  C  C   . GLN A 1 536 ? 200.918 189.281 203.810 1.00 50.66  ? 536 GLN A C   1 
ATOM   4108  O  O   . GLN A 1 536 ? 200.484 190.358 204.233 1.00 50.66  ? 536 GLN A O   1 
ATOM   4109  C  CB  . GLN A 1 536 ? 201.372 187.661 205.620 1.00 50.66  ? 536 GLN A CB  1 
ATOM   4110  C  CG  . GLN A 1 536 ? 202.261 186.572 206.161 1.00 50.66  ? 536 GLN A CG  1 
ATOM   4111  C  CD  . GLN A 1 536 ? 201.534 185.657 207.125 1.00 50.66  ? 536 GLN A CD  1 
ATOM   4112  O  OE1 . GLN A 1 536 ? 200.396 185.920 207.509 1.00 50.66  ? 536 GLN A OE1 1 
ATOM   4113  N  NE2 . GLN A 1 536 ? 202.190 184.571 207.519 1.00 50.66  ? 536 GLN A NE2 1 
ATOM   4114  N  N   . PHE A 1 537 ? 200.466 188.691 202.707 1.00 51.28  ? 537 PHE A N   1 
ATOM   4115  C  CA  . PHE A 1 537 ? 199.155 188.981 202.143 1.00 51.28  ? 537 PHE A CA  1 
ATOM   4116  C  C   . PHE A 1 537 ? 198.126 188.178 202.929 1.00 51.28  ? 537 PHE A C   1 
ATOM   4117  O  O   . PHE A 1 537 ? 198.406 187.654 204.010 1.00 51.28  ? 537 PHE A O   1 
ATOM   4118  C  CB  . PHE A 1 537 ? 199.089 188.627 200.661 1.00 51.28  ? 537 PHE A CB  1 
ATOM   4119  C  CG  . PHE A 1 537 ? 199.912 189.501 199.782 1.00 51.28  ? 537 PHE A CG  1 
ATOM   4120  C  CD1 . PHE A 1 537 ? 201.287 189.421 199.793 1.00 51.28  ? 537 PHE A CD1 1 
ATOM   4121  C  CD2 . PHE A 1 537 ? 199.310 190.380 198.913 1.00 51.28  ? 537 PHE A CD2 1 
ATOM   4122  C  CE1 . PHE A 1 537 ? 202.042 190.220 198.972 1.00 51.28  ? 537 PHE A CE1 1 
ATOM   4123  C  CE2 . PHE A 1 537 ? 200.058 191.174 198.088 1.00 51.28  ? 537 PHE A CE2 1 
ATOM   4124  C  CZ  . PHE A 1 537 ? 201.426 191.097 198.118 1.00 51.28  ? 537 PHE A CZ  1 
ATOM   4125  N  N   . PHE A 1 538 ? 196.918 188.065 202.397 1.00 58.47  ? 538 PHE A N   1 
ATOM   4126  C  CA  . PHE A 1 538 ? 195.900 187.216 202.992 1.00 58.47  ? 538 PHE A CA  1 
ATOM   4127  C  C   . PHE A 1 538 ? 195.986 185.812 202.413 1.00 58.47  ? 538 PHE A C   1 
ATOM   4128  O  O   . PHE A 1 538 ? 196.184 185.640 201.206 1.00 58.47  ? 538 PHE A O   1 
ATOM   4129  C  CB  . PHE A 1 538 ? 194.513 187.807 202.783 1.00 58.47  ? 538 PHE A CB  1 
ATOM   4130  C  CG  . PHE A 1 538 ? 194.302 189.045 203.561 1.00 58.47  ? 538 PHE A CG  1 
ATOM   4131  C  CD1 . PHE A 1 538 ? 194.779 189.126 204.857 1.00 58.47  ? 538 PHE A CD1 1 
ATOM   4132  C  CD2 . PHE A 1 538 ? 193.649 190.129 203.014 1.00 58.47  ? 538 PHE A CD2 1 
ATOM   4133  C  CE1 . PHE A 1 538 ? 194.606 190.261 205.596 1.00 58.47  ? 538 PHE A CE1 1 
ATOM   4134  C  CE2 . PHE A 1 538 ? 193.469 191.274 203.753 1.00 58.47  ? 538 PHE A CE2 1 
ATOM   4135  C  CZ  . PHE A 1 538 ? 193.954 191.341 205.043 1.00 58.47  ? 538 PHE A CZ  1 
ATOM   4136  N  N   . SER A 1 539 ? 195.840 184.819 203.286 1.00 61.97  ? 539 SER A N   1 
ATOM   4137  C  CA  . SER A 1 539 ? 196.029 183.421 202.906 1.00 61.97  ? 539 SER A CA  1 
ATOM   4138  C  C   . SER A 1 539 ? 195.140 182.948 201.761 1.00 61.97  ? 539 SER A C   1 
ATOM   4139  O  O   . SER A 1 539 ? 195.654 182.256 200.868 1.00 61.97  ? 539 SER A O   1 
ATOM   4140  C  CB  . SER A 1 539 ? 195.827 182.539 204.146 1.00 61.97  ? 539 SER A CB  1 
ATOM   4141  O  OG  . SER A 1 539 ? 196.807 182.814 205.132 1.00 61.97  ? 539 SER A OG  1 
ATOM   4142  N  N   . PRO A 1 540 ? 193.828 183.256 201.715 1.00 62.17  ? 540 PRO A N   1 
ATOM   4143  C  CA  . PRO A 1 540 ? 192.957 182.565 200.752 1.00 62.17  ? 540 PRO A CA  1 
ATOM   4144  C  C   . PRO A 1 540 ? 193.384 182.691 199.300 1.00 62.17  ? 540 PRO A C   1 
ATOM   4145  O  O   . PRO A 1 540 ? 193.161 181.767 198.513 1.00 62.17  ? 540 PRO A O   1 
ATOM   4146  C  CB  . PRO A 1 540 ? 191.595 183.230 200.979 1.00 62.17  ? 540 PRO A CB  1 
ATOM   4147  C  CG  . PRO A 1 540 ? 191.626 183.657 202.383 1.00 62.17  ? 540 PRO A CG  1 
ATOM   4148  C  CD  . PRO A 1 540 ? 193.038 184.093 202.638 1.00 62.17  ? 540 PRO A CD  1 
ATOM   4149  N  N   . ALA A 1 541 ? 193.979 183.799 198.925 1.00 59.06  ? 541 ALA A N   1 
ATOM   4150  C  CA  . ALA A 1 541 ? 194.220 183.933 197.494 1.00 59.06  ? 541 ALA A CA  1 
ATOM   4151  C  C   . ALA A 1 541 ? 195.687 184.055 197.117 1.00 59.06  ? 541 ALA A C   1 
ATOM   4152  O  O   . ALA A 1 541 ? 196.165 183.276 196.292 1.00 59.06  ? 541 ALA A O   1 
ATOM   4153  C  CB  . ALA A 1 541 ? 193.447 185.146 196.951 1.00 59.06  ? 541 ALA A CB  1 
ATOM   4154  N  N   . MET A 1 542 ? 196.414 185.009 197.692 1.00 59.76  ? 542 MET A N   1 
ATOM   4155  C  CA  . MET A 1 542 ? 197.696 185.403 197.134 1.00 59.76  ? 542 MET A CA  1 
ATOM   4156  C  C   . MET A 1 542 ? 198.878 185.279 198.082 1.00 59.76  ? 542 MET A C   1 
ATOM   4157  O  O   . MET A 1 542 ? 200.022 185.347 197.613 1.00 59.76  ? 542 MET A O   1 
ATOM   4158  C  CB  . MET A 1 542 ? 197.620 186.841 196.604 1.00 59.76  ? 542 MET A CB  1 
ATOM   4159  C  CG  . MET A 1 542 ? 197.372 187.886 197.662 1.00 59.76  ? 542 MET A CG  1 
ATOM   4160  S  SD  . MET A 1 542 ? 196.702 189.402 196.963 1.00 59.76  ? 542 MET A SD  1 
ATOM   4161  C  CE  . MET A 1 542 ? 197.900 189.747 195.678 1.00 59.76  ? 542 MET A CE  1 
ATOM   4162  N  N   . ASN A 1 543 ? 198.657 185.088 199.383 1.00 57.87  ? 543 ASN A N   1 
ATOM   4163  C  CA  . ASN A 1 543 ? 199.772 184.699 200.237 1.00 57.87  ? 543 ASN A CA  1 
ATOM   4164  C  C   . ASN A 1 543 ? 200.375 183.383 199.771 1.00 57.87  ? 543 ASN A C   1 
ATOM   4165  O  O   . ASN A 1 543 ? 201.586 183.176 199.891 1.00 57.87  ? 543 ASN A O   1 
ATOM   4166  C  CB  . ASN A 1 543 ? 199.318 184.594 201.689 1.00 57.87  ? 543 ASN A CB  1 
ATOM   4167  C  CG  . ASN A 1 543 ? 200.466 184.735 202.669 1.00 57.87  ? 543 ASN A CG  1 
ATOM   4168  O  OD1 . ASN A 1 543 ? 201.627 184.525 202.319 1.00 57.87  ? 543 ASN A OD1 1 
ATOM   4169  N  ND2 . ASN A 1 543 ? 200.145 185.091 203.907 1.00 57.87  ? 543 ASN A ND2 1 
ATOM   4170  N  N   . GLU A 1 544 ? 199.549 182.487 199.227 1.00 62.27  ? 544 GLU A N   1 
ATOM   4171  C  CA  . GLU A 1 544 ? 200.067 181.273 198.610 1.00 62.27  ? 544 GLU A CA  1 
ATOM   4172  C  C   . GLU A 1 544 ? 200.656 181.545 197.229 1.00 62.27  ? 544 GLU A C   1 
ATOM   4173  O  O   . GLU A 1 544 ? 201.560 180.826 196.792 1.00 62.27  ? 544 GLU A O   1 
ATOM   4174  C  CB  . GLU A 1 544 ? 198.964 180.219 198.512 1.00 62.27  ? 544 GLU A CB  1 
ATOM   4175  C  CG  . GLU A 1 544 ? 197.783 180.625 197.639 1.00 62.27  ? 544 GLU A CG  1 
ATOM   4176  C  CD  . GLU A 1 544 ? 197.986 180.267 196.177 1.00 62.27  ? 544 GLU A CD  1 
ATOM   4177  O  OE1 . GLU A 1 544 ? 198.746 179.318 195.897 1.00 62.27  ? 544 GLU A OE1 1 
ATOM   4178  O  OE2 . GLU A 1 544 ? 197.396 180.942 195.309 1.00 62.27  ? 544 GLU A OE2 1 
ATOM   4179  N  N   . MET A 1 545 ? 200.143 182.553 196.517 1.00 63.54  ? 545 MET A N   1 
ATOM   4180  C  CA  . MET A 1 545 ? 200.674 182.869 195.193 1.00 63.54  ? 545 MET A CA  1 
ATOM   4181  C  C   . MET A 1 545 ? 202.096 183.400 195.288 1.00 63.54  ? 545 MET A C   1 
ATOM   4182  O  O   . MET A 1 545 ? 202.925 183.151 194.404 1.00 63.54  ? 545 MET A O   1 
ATOM   4183  C  CB  . MET A 1 545 ? 199.766 183.882 194.496 1.00 63.54  ? 545 MET A CB  1 
ATOM   4184  C  CG  . MET A 1 545 ? 200.184 184.233 193.082 1.00 63.54  ? 545 MET A CG  1 
ATOM   4185  S  SD  . MET A 1 545 ? 199.085 185.443 192.326 1.00 63.54  ? 545 MET A SD  1 
ATOM   4186  C  CE  . MET A 1 545 ? 197.618 184.449 192.065 1.00 63.54  ? 545 MET A CE  1 
ATOM   4187  N  N   . VAL A 1 546 ? 202.388 184.146 196.348 1.00 57.23  ? 546 VAL A N   1 
ATOM   4188  C  CA  . VAL A 1 546 ? 203.759 184.572 196.602 1.00 57.23  ? 546 VAL A CA  1 
ATOM   4189  C  C   . VAL A 1 546 ? 204.668 183.358 196.709 1.00 57.23  ? 546 VAL A C   1 
ATOM   4190  O  O   . VAL A 1 546 ? 205.758 183.316 196.120 1.00 57.23  ? 546 VAL A O   1 
ATOM   4191  C  CB  . VAL A 1 546 ? 203.818 185.435 197.873 1.00 57.23  ? 546 VAL A CB  1 
ATOM   4192  C  CG1 . VAL A 1 546 ? 205.232 185.491 198.408 1.00 57.23  ? 546 VAL A CG1 1 
ATOM   4193  C  CG2 . VAL A 1 546 ? 203.307 186.828 197.584 1.00 57.23  ? 546 VAL A CG2 1 
ATOM   4194  N  N   . LYS A 1 547 ? 204.223 182.338 197.445 1.00 63.03  ? 547 LYS A N   1 
ATOM   4195  C  CA  . LYS A 1 547 ? 205.024 181.128 197.595 1.00 63.03  ? 547 LYS A CA  1 
ATOM   4196  C  C   . LYS A 1 547 ? 205.131 180.368 196.280 1.00 63.03  ? 547 LYS A C   1 
ATOM   4197  O  O   . LYS A 1 547 ? 206.167 179.760 195.992 1.00 63.03  ? 547 LYS A O   1 
ATOM   4198  C  CB  . LYS A 1 547 ? 204.430 180.241 198.688 1.00 63.03  ? 547 LYS A CB  1 
ATOM   4199  C  CG  . LYS A 1 547 ? 205.386 179.190 199.213 1.00 63.03  ? 547 LYS A CG  1 
ATOM   4200  C  CD  . LYS A 1 547 ? 206.637 179.835 199.782 1.00 63.03  ? 547 LYS A CD  1 
ATOM   4201  C  CE  . LYS A 1 547 ? 206.307 180.744 200.954 1.00 63.03  ? 547 LYS A CE  1 
ATOM   4202  N  NZ  . LYS A 1 547 ? 205.745 179.984 202.102 1.00 63.03  ? 547 LYS A NZ  1 
ATOM   4203  N  N   . GLU A 1 548 ? 204.069 180.383 195.474 1.00 63.36  ? 548 GLU A N   1 
ATOM   4204  C  CA  . GLU A 1 548 ? 204.127 179.746 194.161 1.00 63.36  ? 548 GLU A CA  1 
ATOM   4205  C  C   . GLU A 1 548 ? 205.183 180.404 193.280 1.00 63.36  ? 548 GLU A C   1 
ATOM   4206  O  O   . GLU A 1 548 ? 205.973 179.722 192.612 1.00 63.36  ? 548 GLU A O   1 
ATOM   4207  C  CB  . GLU A 1 548 ? 202.756 179.803 193.494 1.00 63.36  ? 548 GLU A CB  1 
ATOM   4208  C  CG  . GLU A 1 548 ? 201.718 178.910 194.145 1.00 63.36  ? 548 GLU A CG  1 
ATOM   4209  C  CD  . GLU A 1 548 ? 202.078 177.441 194.058 1.00 63.36  ? 548 GLU A CD  1 
ATOM   4210  O  OE1 . GLU A 1 548 ? 202.592 177.015 193.002 1.00 63.36  ? 548 GLU A OE1 1 
ATOM   4211  O  OE2 . GLU A 1 548 ? 201.849 176.712 195.046 1.00 63.36  ? 548 GLU A OE2 1 
ATOM   4212  N  N   . ARG A 1 549 ? 205.218 181.736 193.275 1.00 59.04  ? 549 ARG A N   1 
ATOM   4213  C  CA  . ARG A 1 549 ? 206.239 182.438 192.507 1.00 59.04  ? 549 ARG A CA  1 
ATOM   4214  C  C   . ARG A 1 549 ? 207.633 182.160 193.055 1.00 59.04  ? 549 ARG A C   1 
ATOM   4215  O  O   . ARG A 1 549 ? 208.593 182.022 192.288 1.00 59.04  ? 549 ARG A O   1 
ATOM   4216  C  CB  . ARG A 1 549 ? 205.962 183.938 192.493 1.00 59.04  ? 549 ARG A CB  1 
ATOM   4217  C  CG  . ARG A 1 549 ? 206.898 184.703 191.582 1.00 59.04  ? 549 ARG A CG  1 
ATOM   4218  C  CD  . ARG A 1 549 ? 206.518 186.160 191.477 1.00 59.04  ? 549 ARG A CD  1 
ATOM   4219  N  NE  . ARG A 1 549 ? 207.449 186.891 190.629 1.00 59.04  ? 549 ARG A NE  1 
ATOM   4220  C  CZ  . ARG A 1 549 ? 207.343 186.983 189.311 1.00 59.04  ? 549 ARG A CZ  1 
ATOM   4221  N  NH1 . ARG A 1 549 ? 206.351 186.404 188.656 1.00 59.04  ? 549 ARG A NH1 1 
ATOM   4222  N  NH2 . ARG A 1 549 ? 208.254 187.675 188.634 1.00 59.04  ? 549 ARG A NH2 1 
ATOM   4223  N  N   . LEU A 1 550 ? 207.772 182.076 194.379 1.00 56.01  ? 550 LEU A N   1 
ATOM   4224  C  CA  . LEU A 1 550 ? 209.081 181.770 194.946 1.00 56.01  ? 550 LEU A CA  1 
ATOM   4225  C  C   . LEU A 1 550 ? 209.535 180.371 194.545 1.00 56.01  ? 550 LEU A C   1 
ATOM   4226  O  O   . LEU A 1 550 ? 210.723 180.143 194.278 1.00 56.01  ? 550 LEU A O   1 
ATOM   4227  C  CB  . LEU A 1 550 ? 209.039 181.921 196.466 1.00 56.01  ? 550 LEU A CB  1 
ATOM   4228  C  CG  . LEU A 1 550 ? 210.360 181.881 197.242 1.00 56.01  ? 550 LEU A CG  1 
ATOM   4229  C  CD1 . LEU A 1 550 ? 210.250 182.730 198.495 1.00 56.01  ? 550 LEU A CD1 1 
ATOM   4230  C  CD2 . LEU A 1 550 ? 210.755 180.458 197.616 1.00 56.01  ? 550 LEU A CD2 1 
ATOM   4231  N  N   . VAL A 1 551 ? 208.605 179.419 194.507 1.00 57.59  ? 551 VAL A N   1 
ATOM   4232  C  CA  . VAL A 1 551 ? 208.940 178.067 194.073 1.00 57.59  ? 551 VAL A CA  1 
ATOM   4233  C  C   . VAL A 1 551 ? 209.366 178.073 192.613 1.00 57.59  ? 551 VAL A C   1 
ATOM   4234  O  O   . VAL A 1 551 ? 210.323 177.390 192.227 1.00 57.59  ? 551 VAL A O   1 
ATOM   4235  C  CB  . VAL A 1 551 ? 207.753 177.116 194.319 1.00 57.59  ? 551 VAL A CB  1 
ATOM   4236  C  CG1 . VAL A 1 551 ? 207.967 175.794 193.600 1.00 57.59  ? 551 VAL A CG1 1 
ATOM   4237  C  CG2 . VAL A 1 551 ? 207.565 176.882 195.810 1.00 57.59  ? 551 VAL A CG2 1 
ATOM   4238  N  N   . LEU A 1 552 ? 208.663 178.837 191.775 1.00 54.39  ? 552 LEU A N   1 
ATOM   4239  C  CA  . LEU A 1 552 ? 209.095 178.970 190.387 1.00 54.39  ? 552 LEU A CA  1 
ATOM   4240  C  C   . LEU A 1 552 ? 210.493 179.569 190.311 1.00 54.39  ? 552 LEU A C   1 
ATOM   4241  O  O   . LEU A 1 552 ? 211.288 179.198 189.444 1.00 54.39  ? 552 LEU A O   1 
ATOM   4242  C  CB  . LEU A 1 552 ? 208.107 179.820 189.593 1.00 54.39  ? 552 LEU A CB  1 
ATOM   4243  C  CG  . LEU A 1 552 ? 208.297 179.801 188.077 1.00 54.39  ? 552 LEU A CG  1 
ATOM   4244  C  CD1 . LEU A 1 552 ? 207.772 178.513 187.524 1.00 54.39  ? 552 LEU A CD1 1 
ATOM   4245  C  CD2 . LEU A 1 552 ? 207.603 180.964 187.422 1.00 54.39  ? 552 LEU A CD2 1 
ATOM   4246  N  N   . GLY A 1 553 ? 210.810 180.498 191.210 1.00 57.91  ? 553 GLY A N   1 
ATOM   4247  C  CA  . GLY A 1 553 ? 212.152 181.056 191.230 1.00 57.91  ? 553 GLY A CA  1 
ATOM   4248  C  C   . GLY A 1 553 ? 213.201 180.015 191.566 1.00 57.91  ? 553 GLY A C   1 
ATOM   4249  O  O   . GLY A 1 553 ? 214.269 179.959 190.947 1.00 57.91  ? 553 GLY A O   1 
ATOM   4250  N  N   . ALA A 1 554 ? 212.908 179.175 192.556 1.00 53.35  ? 554 ALA A N   1 
ATOM   4251  C  CA  . ALA A 1 554 ? 213.829 178.096 192.896 1.00 53.35  ? 554 ALA A CA  1 
ATOM   4252  C  C   . ALA A 1 554 ? 214.002 177.147 191.720 1.00 53.35  ? 554 ALA A C   1 
ATOM   4253  O  O   . ALA A 1 554 ? 215.113 176.678 191.437 1.00 53.35  ? 554 ALA A O   1 
ATOM   4254  C  CB  . ALA A 1 554 ? 213.330 177.342 194.125 1.00 53.35  ? 554 ALA A CB  1 
ATOM   4255  N  N   . ALA A 1 555 ? 212.910 176.869 191.011 1.00 55.28  ? 555 ALA A N   1 
ATOM   4256  C  CA  . ALA A 1 555 ? 212.986 176.004 189.842 1.00 55.28  ? 555 ALA A CA  1 
ATOM   4257  C  C   . ALA A 1 555 ? 213.830 176.635 188.745 1.00 55.28  ? 555 ALA A C   1 
ATOM   4258  O  O   . ALA A 1 555 ? 214.574 175.940 188.048 1.00 55.28  ? 555 ALA A O   1 
ATOM   4259  C  CB  . ALA A 1 555 ? 211.582 175.689 189.327 1.00 55.28  ? 555 ALA A CB  1 
ATOM   4260  N  N   . LEU A 1 556 ? 213.711 177.950 188.562 1.00 55.55  ? 556 LEU A N   1 
ATOM   4261  C  CA  . LEU A 1 556 ? 214.526 178.626 187.560 1.00 55.55  ? 556 LEU A CA  1 
ATOM   4262  C  C   . LEU A 1 556 ? 215.996 178.560 187.928 1.00 55.55  ? 556 LEU A C   1 
ATOM   4263  O  O   . LEU A 1 556 ? 216.854 178.390 187.056 1.00 55.55  ? 556 LEU A O   1 
ATOM   4264  C  CB  . LEU A 1 556 ? 214.080 180.076 187.392 1.00 55.55  ? 556 LEU A CB  1 
ATOM   4265  C  CG  . LEU A 1 556 ? 214.670 180.808 186.183 1.00 55.55  ? 556 LEU A CG  1 
ATOM   4266  C  CD1 . LEU A 1 556 ? 213.659 181.775 185.610 1.00 55.55  ? 556 LEU A CD1 1 
ATOM   4267  C  CD2 . LEU A 1 556 ? 215.947 181.546 186.539 1.00 55.55  ? 556 LEU A CD2 1 
ATOM   4268  N  N   . LYS A 1 557 ? 216.307 178.711 189.213 1.00 58.61  ? 557 LYS A N   1 
ATOM   4269  C  CA  . LYS A 1 557 ? 217.687 178.545 189.652 1.00 58.61  ? 557 LYS A CA  1 
ATOM   4270  C  C   . LYS A 1 557 ? 218.188 177.148 189.320 1.00 58.61  ? 557 LYS A C   1 
ATOM   4271  O  O   . LYS A 1 557 ? 219.290 176.976 188.784 1.00 58.61  ? 557 LYS A O   1 
ATOM   4272  C  CB  . LYS A 1 557 ? 217.795 178.812 191.152 1.00 58.61  ? 557 LYS A CB  1 
ATOM   4273  C  CG  . LYS A 1 557 ? 219.201 179.122 191.628 1.00 58.61  ? 557 LYS A CG  1 
ATOM   4274  C  CD  . LYS A 1 557 ? 219.260 179.250 193.142 1.00 58.61  ? 557 LYS A CD  1 
ATOM   4275  C  CE  . LYS A 1 557 ? 218.220 180.227 193.672 1.00 58.61  ? 557 LYS A CE  1 
ATOM   4276  N  NZ  . LYS A 1 557 ? 218.183 181.501 192.902 1.00 58.61  ? 557 LYS A NZ  1 
ATOM   4277  N  N   . GLU A 1 558 ? 217.371 176.135 189.606 1.00 60.27  ? 558 GLU A N   1 
ATOM   4278  C  CA  . GLU A 1 558 ? 217.768 174.762 189.313 1.00 60.27  ? 558 GLU A CA  1 
ATOM   4279  C  C   . GLU A 1 558 ? 218.005 174.566 187.821 1.00 60.27  ? 558 GLU A C   1 
ATOM   4280  O  O   . GLU A 1 558 ? 218.989 173.940 187.413 1.00 60.27  ? 558 GLU A O   1 
ATOM   4281  C  CB  . GLU A 1 558 ? 216.702 173.792 189.823 1.00 60.27  ? 558 GLU A CB  1 
ATOM   4282  C  CG  . GLU A 1 558 ? 217.115 172.330 189.791 1.00 60.27  ? 558 GLU A CG  1 
ATOM   4283  C  CD  . GLU A 1 558 ? 216.738 171.641 188.494 1.00 60.27  ? 558 GLU A CD  1 
ATOM   4284  O  OE1 . GLU A 1 558 ? 215.749 172.066 187.861 1.00 60.27  ? 558 GLU A OE1 1 
ATOM   4285  O  OE2 . GLU A 1 558 ? 217.428 170.673 188.110 1.00 60.27  ? 558 GLU A OE2 1 
ATOM   4286  N  N   . ALA A 1 559 ? 217.110 175.102 186.993 1.00 59.67  ? 559 ALA A N   1 
ATOM   4287  C  CA  . ALA A 1 559 ? 217.212 174.901 185.551 1.00 59.67  ? 559 ALA A CA  1 
ATOM   4288  C  C   . ALA A 1 559 ? 218.420 175.622 184.965 1.00 59.67  ? 559 ALA A C   1 
ATOM   4289  O  O   . ALA A 1 559 ? 219.126 175.067 184.113 1.00 59.67  ? 559 ALA A O   1 
ATOM   4290  C  CB  . ALA A 1 559 ? 215.926 175.363 184.867 1.00 59.67  ? 559 ALA A CB  1 
ATOM   4291  N  N   . ILE A 1 560 ? 218.673 176.861 185.396 1.00 58.30  ? 560 ILE A N   1 
ATOM   4292  C  CA  . ILE A 1 560 ? 219.832 177.584 184.885 1.00 58.30  ? 560 ILE A CA  1 
ATOM   4293  C  C   . ILE A 1 560 ? 221.118 176.943 185.380 1.00 58.30  ? 560 ILE A C   1 
ATOM   4294  O  O   . ILE A 1 560 ? 222.148 177.000 184.699 1.00 58.30  ? 560 ILE A O   1 
ATOM   4295  C  CB  . ILE A 1 560 ? 219.759 179.077 185.251 1.00 58.30  ? 560 ILE A CB  1 
ATOM   4296  C  CG1 . ILE A 1 560 ? 220.875 179.855 184.553 1.00 58.30  ? 560 ILE A CG1 1 
ATOM   4297  C  CG2 . ILE A 1 560 ? 219.875 179.277 186.745 1.00 58.30  ? 560 ILE A CG2 1 
ATOM   4298  C  CD1 . ILE A 1 560 ? 220.949 179.626 183.065 1.00 58.30  ? 560 ILE A CD1 1 
ATOM   4299  N  N   . SER A 1 561 ? 221.091 176.316 186.555 1.00 55.06  ? 561 SER A N   1 
ATOM   4300  C  CA  . SER A 1 561 ? 222.267 175.585 187.008 1.00 55.06  ? 561 SER A CA  1 
ATOM   4301  C  C   . SER A 1 561 ? 222.503 174.348 186.154 1.00 55.06  ? 561 SER A C   1 
ATOM   4302  O  O   . SER A 1 561 ? 223.617 174.118 185.671 1.00 55.06  ? 561 SER A O   1 
ATOM   4303  C  CB  . SER A 1 561 ? 222.105 175.198 188.475 1.00 55.06  ? 561 SER A CB  1 
ATOM   4304  O  OG  . SER A 1 561 ? 220.973 174.365 188.646 1.00 55.06  ? 561 SER A OG  1 
ATOM   4305  N  N   . ASN A 1 562 ? 221.462 173.550 185.938 1.00 53.99  ? 562 ASN A N   1 
ATOM   4306  C  CA  . ASN A 1 562 ? 221.589 172.261 185.263 1.00 53.99  ? 562 ASN A CA  1 
ATOM   4307  C  C   . ASN A 1 562 ? 221.091 172.306 183.828 1.00 53.99  ? 562 ASN A C   1 
ATOM   4308  O  O   . ASN A 1 562 ? 220.462 171.354 183.363 1.00 53.99  ? 562 ASN A O   1 
ATOM   4309  C  CB  . ASN A 1 562 ? 220.852 171.186 186.050 1.00 53.99  ? 562 ASN A CB  1 
ATOM   4310  C  CG  . ASN A 1 562 ? 221.611 170.752 187.279 1.00 53.99  ? 562 ASN A CG  1 
ATOM   4311  O  OD1 . ASN A 1 562 ? 222.729 171.204 187.519 1.00 53.99  ? 562 ASN A OD1 1 
ATOM   4312  N  ND2 . ASN A 1 562 ? 221.008 169.873 188.069 1.00 53.99  ? 562 ASN A ND2 1 
ATOM   4313  N  N   . ASN A 1 563 ? 221.326 173.427 183.143 1.00 53.19  ? 563 ASN A N   1 
ATOM   4314  C  CA  . ASN A 1 563 ? 221.153 173.576 181.691 1.00 53.19  ? 563 ASN A CA  1 
ATOM   4315  C  C   . ASN A 1 563 ? 219.883 172.902 181.174 1.00 53.19  ? 563 ASN A C   1 
ATOM   4316  O  O   . ASN A 1 563 ? 219.884 172.201 180.160 1.00 53.19  ? 563 ASN A O   1 
ATOM   4317  C  CB  . ASN A 1 563 ? 222.402 173.105 180.933 1.00 53.19  ? 563 ASN A CB  1 
ATOM   4318  C  CG  . ASN A 1 563 ? 222.715 171.624 181.117 1.00 53.19  ? 563 ASN A CG  1 
ATOM   4319  O  OD1 . ASN A 1 563 ? 221.830 170.787 181.262 1.00 53.19  ? 563 ASN A OD1 1 
ATOM   4320  N  ND2 . ASN A 1 563 ? 224.003 171.301 181.112 1.00 53.19  ? 563 ASN A ND2 1 
ATOM   4321  N  N   . GLN A 1 564 ? 218.780 173.136 181.874 1.00 57.28  ? 564 GLN A N   1 
ATOM   4322  C  CA  . GLN A 1 564 ? 217.487 172.655 181.421 1.00 57.28  ? 564 GLN A CA  1 
ATOM   4323  C  C   . GLN A 1 564 ? 216.871 173.544 180.355 1.00 57.28  ? 564 GLN A C   1 
ATOM   4324  O  O   . GLN A 1 564 ? 215.930 173.113 179.681 1.00 57.28  ? 564 GLN A O   1 
ATOM   4325  C  CB  . GLN A 1 564 ? 216.527 172.529 182.605 1.00 57.28  ? 564 GLN A CB  1 
ATOM   4326  C  CG  . GLN A 1 564 ? 216.854 171.364 183.526 1.00 57.28  ? 564 GLN A CG  1 
ATOM   4327  C  CD  . GLN A 1 564 ? 216.790 170.026 182.812 1.00 57.28  ? 564 GLN A CD  1 
ATOM   4328  O  OE1 . GLN A 1 564 ? 215.907 169.789 181.989 1.00 57.28  ? 564 GLN A OE1 1 
ATOM   4329  N  NE2 . GLN A 1 564 ? 217.733 169.145 183.123 1.00 57.28  ? 564 GLN A NE2 1 
ATOM   4330  N  N   . LEU A 1 565 ? 217.383 174.759 180.175 1.00 48.37  ? 565 LEU A N   1 
ATOM   4331  C  CA  . LEU A 1 565 ? 216.873 175.661 179.152 1.00 48.37  ? 565 LEU A CA  1 
ATOM   4332  C  C   . LEU A 1 565 ? 217.245 175.137 177.775 1.00 48.37  ? 565 LEU A C   1 
ATOM   4333  O  O   . LEU A 1 565 ? 217.855 174.071 177.658 1.00 48.37  ? 565 LEU A O   1 
ATOM   4334  C  CB  . LEU A 1 565 ? 217.422 177.074 179.359 1.00 48.37  ? 565 LEU A CB  1 
ATOM   4335  C  CG  . LEU A 1 565 ? 217.519 177.564 180.803 1.00 48.37  ? 565 LEU A CG  1 
ATOM   4336  C  CD1 . LEU A 1 565 ? 218.238 178.889 180.868 1.00 48.37  ? 565 LEU A CD1 1 
ATOM   4337  C  CD2 . LEU A 1 565 ? 216.142 177.680 181.421 1.00 48.37  ? 565 LEU A CD2 1 
ATOM   4338  N  N   . LYS A 1 566 ? 216.886 175.872 176.730 1.00 45.10  ? 566 LYS A N   1 
ATOM   4339  C  CA  . LYS A 1 566 ? 217.244 175.476 175.376 1.00 45.10  ? 566 LYS A CA  1 
ATOM   4340  C  C   . LYS A 1 566 ? 217.093 176.645 174.415 1.00 45.10  ? 566 LYS A C   1 
ATOM   4341  O  O   . LYS A 1 566 ? 216.029 177.267 174.352 1.00 45.10  ? 566 LYS A O   1 
ATOM   4342  C  CB  . LYS A 1 566 ? 216.380 174.304 174.922 1.00 45.10  ? 566 LYS A CB  1 
ATOM   4343  C  CG  . LYS A 1 566 ? 216.624 173.869 173.497 1.00 45.10  ? 566 LYS A CG  1 
ATOM   4344  C  CD  . LYS A 1 566 ? 216.038 172.493 173.249 1.00 45.10  ? 566 LYS A CD  1 
ATOM   4345  C  CE  . LYS A 1 566 ? 214.603 172.423 173.734 1.00 45.10  ? 566 LYS A CE  1 
ATOM   4346  N  NZ  . LYS A 1 566 ? 213.745 173.419 173.042 1.00 45.10  ? 566 LYS A NZ  1 
ATOM   4347  N  N   . LEU A 1 567 ? 218.145 176.959 173.670 1.00 42.51  ? 567 LEU A N   1 
ATOM   4348  C  CA  . LEU A 1 567 ? 218.071 178.028 172.692 1.00 42.51  ? 567 LEU A CA  1 
ATOM   4349  C  C   . LEU A 1 567 ? 217.143 177.627 171.552 1.00 42.51  ? 567 LEU A C   1 
ATOM   4350  O  O   . LEU A 1 567 ? 217.009 176.448 171.223 1.00 42.51  ? 567 LEU A O   1 
ATOM   4351  C  CB  . LEU A 1 567 ? 219.461 178.347 172.155 1.00 42.51  ? 567 LEU A CB  1 
ATOM   4352  C  CG  . LEU A 1 567 ? 219.760 179.803 171.832 1.00 42.51  ? 567 LEU A CG  1 
ATOM   4353  C  CD1 . LEU A 1 567 ? 219.742 180.605 173.109 1.00 42.51  ? 567 LEU A CD1 1 
ATOM   4354  C  CD2 . LEU A 1 567 ? 221.109 179.909 171.161 1.00 42.51  ? 567 LEU A CD2 1 
ATOM   4355  N  N   . VAL A 1 568 ? 216.488 178.623 170.953 1.00 44.60  ? 568 VAL A N   1 
ATOM   4356  C  CA  . VAL A 1 568 ? 215.579 178.401 169.835 1.00 44.60  ? 568 VAL A CA  1 
ATOM   4357  C  C   . VAL A 1 568 ? 215.922 179.379 168.718 1.00 44.60  ? 568 VAL A C   1 
ATOM   4358  O  O   . VAL A 1 568 ? 216.485 180.450 168.959 1.00 44.60  ? 568 VAL A O   1 
ATOM   4359  C  CB  . VAL A 1 568 ? 214.107 178.543 170.266 1.00 44.60  ? 568 VAL A CB  1 
ATOM   4360  C  CG1 . VAL A 1 568 ? 213.758 180.000 170.508 1.00 44.60  ? 568 VAL A CG1 1 
ATOM   4361  C  CG2 . VAL A 1 568 ? 213.184 177.923 169.247 1.00 44.60  ? 568 VAL A CG2 1 
ATOM   4362  N  N   . TYR A 1 569 ? 215.580 179.006 167.487 1.00 48.84  ? 569 TYR A N   1 
ATOM   4363  C  CA  . TYR A 1 569 ? 216.067 179.688 166.298 1.00 48.84  ? 569 TYR A CA  1 
ATOM   4364  C  C   . TYR A 1 569 ? 214.925 180.023 165.352 1.00 48.84  ? 569 TYR A C   1 
ATOM   4365  O  O   . TYR A 1 569 ? 213.969 179.259 165.207 1.00 48.84  ? 569 TYR A O   1 
ATOM   4366  C  CB  . TYR A 1 569 ? 217.096 178.830 165.590 1.00 48.84  ? 569 TYR A CB  1 
ATOM   4367  C  CG  . TYR A 1 569 ? 218.231 178.471 166.498 1.00 48.84  ? 569 TYR A CG  1 
ATOM   4368  C  CD1 . TYR A 1 569 ? 219.096 179.445 166.968 1.00 48.84  ? 569 TYR A CD1 1 
ATOM   4369  C  CD2 . TYR A 1 569 ? 218.427 177.167 166.920 1.00 48.84  ? 569 TYR A CD2 1 
ATOM   4370  C  CE1 . TYR A 1 569 ? 220.137 179.134 167.816 1.00 48.84  ? 569 TYR A CE1 1 
ATOM   4371  C  CE2 . TYR A 1 569 ? 219.467 176.844 167.773 1.00 48.84  ? 569 TYR A CE2 1 
ATOM   4372  C  CZ  . TYR A 1 569 ? 220.318 177.834 168.216 1.00 48.84  ? 569 TYR A CZ  1 
ATOM   4373  O  OH  . TYR A 1 569 ? 221.353 177.527 169.063 1.00 48.84  ? 569 TYR A OH  1 
ATOM   4374  N  N   . GLN A 1 570 ? 215.048 181.178 164.696 1.00 54.56  ? 570 GLN A N   1 
ATOM   4375  C  CA  . GLN A 1 570 ? 214.018 181.723 163.821 1.00 54.56  ? 570 GLN A CA  1 
ATOM   4376  C  C   . GLN A 1 570 ? 214.667 182.461 162.657 1.00 54.56  ? 570 GLN A C   1 
ATOM   4377  O  O   . GLN A 1 570 ? 215.391 183.441 162.867 1.00 54.56  ? 570 GLN A O   1 
ATOM   4378  C  CB  . GLN A 1 570 ? 213.101 182.646 164.615 1.00 54.56  ? 570 GLN A CB  1 
ATOM   4379  C  CG  . GLN A 1 570 ? 212.427 183.719 163.809 1.00 54.56  ? 570 GLN A CG  1 
ATOM   4380  C  CD  . GLN A 1 570 ? 211.343 184.408 164.600 1.00 54.56  ? 570 GLN A CD  1 
ATOM   4381  O  OE1 . GLN A 1 570 ? 211.092 184.060 165.752 1.00 54.56  ? 570 GLN A OE1 1 
ATOM   4382  N  NE2 . GLN A 1 570 ? 210.691 185.389 163.987 1.00 54.56  ? 570 GLN A NE2 1 
ATOM   4383  N  N   . PRO A 1 571 ? 214.431 182.028 161.424 1.00 55.49  ? 571 PRO A N   1 
ATOM   4384  C  CA  . PRO A 1 571 ? 215.245 182.500 160.300 1.00 55.49  ? 571 PRO A CA  1 
ATOM   4385  C  C   . PRO A 1 571 ? 214.908 183.926 159.905 1.00 55.49  ? 571 PRO A C   1 
ATOM   4386  O  O   . PRO A 1 571 ? 213.882 184.491 160.283 1.00 55.49  ? 571 PRO A O   1 
ATOM   4387  C  CB  . PRO A 1 571 ? 214.896 181.522 159.180 1.00 55.49  ? 571 PRO A CB  1 
ATOM   4388  C  CG  . PRO A 1 571 ? 213.506 181.093 159.496 1.00 55.49  ? 571 PRO A CG  1 
ATOM   4389  C  CD  . PRO A 1 571 ? 213.415 181.053 160.999 1.00 55.49  ? 571 PRO A CD  1 
ATOM   4390  N  N   . GLN A 1 572 ? 215.817 184.509 159.128 1.00 56.89  ? 572 GLN A N   1 
ATOM   4391  C  CA  . GLN A 1 572 ? 215.624 185.804 158.492 1.00 56.89  ? 572 GLN A CA  1 
ATOM   4392  C  C   . GLN A 1 572 ? 215.896 185.654 157.005 1.00 56.89  ? 572 GLN A C   1 
ATOM   4393  O  O   . GLN A 1 572 ? 216.840 184.964 156.609 1.00 56.89  ? 572 GLN A O   1 
ATOM   4394  C  CB  . GLN A 1 572 ? 216.546 186.874 159.085 1.00 56.89  ? 572 GLN A CB  1 
ATOM   4395  C  CG  . GLN A 1 572 ? 216.547 186.930 160.602 1.00 56.89  ? 572 GLN A CG  1 
ATOM   4396  C  CD  . GLN A 1 572 ? 217.354 188.092 161.142 1.00 56.89  ? 572 GLN A CD  1 
ATOM   4397  O  OE1 . GLN A 1 572 ? 216.929 189.242 161.075 1.00 56.89  ? 572 GLN A OE1 1 
ATOM   4398  N  NE2 . GLN A 1 572 ? 218.531 187.795 161.675 1.00 56.89  ? 572 GLN A NE2 1 
ATOM   4399  N  N   . ILE A 1 573 ? 215.070 186.290 156.180 1.00 58.59  ? 573 ILE A N   1 
ATOM   4400  C  CA  . ILE A 1 573 ? 215.163 186.155 154.732 1.00 58.59  ? 573 ILE A CA  1 
ATOM   4401  C  C   . ILE A 1 573 ? 215.145 187.538 154.105 1.00 58.59  ? 573 ILE A C   1 
ATOM   4402  O  O   . ILE A 1 573 ? 214.320 188.380 154.477 1.00 58.59  ? 573 ILE A O   1 
ATOM   4403  C  CB  . ILE A 1 573 ? 214.019 185.294 154.170 1.00 58.59  ? 573 ILE A CB  1 
ATOM   4404  C  CG1 . ILE A 1 573 ? 214.037 183.904 154.804 1.00 58.59  ? 573 ILE A CG1 1 
ATOM   4405  C  CG2 . ILE A 1 573 ? 214.119 185.190 152.655 1.00 58.59  ? 573 ILE A CG2 1 
ATOM   4406  C  CD1 . ILE A 1 573 ? 215.258 183.084 154.448 1.00 58.59  ? 573 ILE A CD1 1 
ATOM   4407  N  N   . PHE A 1 574 ? 216.052 187.770 153.155 1.00 59.35  ? 574 PHE A N   1 
ATOM   4408  C  CA  . PHE A 1 574 ? 216.081 189.019 152.404 1.00 59.35  ? 574 PHE A CA  1 
ATOM   4409  C  C   . PHE A 1 574 ? 214.732 189.240 151.739 1.00 59.35  ? 574 PHE A C   1 
ATOM   4410  O  O   . PHE A 1 574 ? 214.161 188.310 151.166 1.00 59.35  ? 574 PHE A O   1 
ATOM   4411  C  CB  . PHE A 1 574 ? 217.194 188.994 151.348 1.00 59.35  ? 574 PHE A CB  1 
ATOM   4412  C  CG  . PHE A 1 574 ? 218.560 189.357 151.877 1.00 59.35  ? 574 PHE A CG  1 
ATOM   4413  C  CD1 . PHE A 1 574 ? 219.160 188.606 152.868 1.00 59.35  ? 574 PHE A CD1 1 
ATOM   4414  C  CD2 . PHE A 1 574 ? 219.249 190.441 151.362 1.00 59.35  ? 574 PHE A CD2 1 
ATOM   4415  C  CE1 . PHE A 1 574 ? 220.406 188.936 153.338 1.00 59.35  ? 574 PHE A CE1 1 
ATOM   4416  C  CE2 . PHE A 1 574 ? 220.494 190.769 151.833 1.00 59.35  ? 574 PHE A CE2 1 
ATOM   4417  C  CZ  . PHE A 1 574 ? 221.072 190.018 152.822 1.00 59.35  ? 574 PHE A CZ  1 
ATOM   4418  N  N   . ALA A 1 575 ? 214.200 190.456 151.823 1.00 64.74  ? 575 ALA A N   1 
ATOM   4419  C  CA  . ALA A 1 575 ? 212.940 190.755 151.154 1.00 64.74  ? 575 ALA A CA  1 
ATOM   4420  C  C   . ALA A 1 575 ? 213.113 190.700 149.643 1.00 64.74  ? 575 ALA A C   1 
ATOM   4421  O  O   . ALA A 1 575 ? 212.346 190.030 148.946 1.00 64.74  ? 575 ALA A O   1 
ATOM   4422  C  CB  . ALA A 1 575 ? 212.413 192.124 151.591 1.00 64.74  ? 575 ALA A CB  1 
ATOM   4423  N  N   . GLU A 1 576 ? 214.114 191.403 149.125 1.00 71.70  ? 576 GLU A N   1 
ATOM   4424  C  CA  . GLU A 1 576 ? 214.528 191.178 147.751 1.00 71.70  ? 576 GLU A CA  1 
ATOM   4425  C  C   . GLU A 1 576 ? 215.014 189.746 147.626 1.00 71.70  ? 576 GLU A C   1 
ATOM   4426  O  O   . GLU A 1 576 ? 215.977 189.355 148.293 1.00 71.70  ? 576 GLU A O   1 
ATOM   4427  C  CB  . GLU A 1 576 ? 215.628 192.163 147.357 1.00 71.70  ? 576 GLU A CB  1 
ATOM   4428  C  CG  . GLU A 1 576 ? 215.157 193.604 147.241 1.00 71.70  ? 576 GLU A CG  1 
ATOM   4429  C  CD  . GLU A 1 576 ? 214.150 193.801 146.124 1.00 71.70  ? 576 GLU A CD  1 
ATOM   4430  O  OE1 . GLU A 1 576 ? 214.272 193.121 145.083 1.00 71.70  ? 576 GLU A OE1 1 
ATOM   4431  O  OE2 . GLU A 1 576 ? 213.235 194.635 146.287 1.00 71.70  ? 576 GLU A OE2 1 
ATOM   4432  N  N   . THR A 1 577 ? 214.335 188.970 146.779 1.00 70.33  ? 577 THR A N   1 
ATOM   4433  C  CA  . THR A 1 577 ? 214.437 187.515 146.760 1.00 70.33  ? 577 THR A CA  1 
ATOM   4434  C  C   . THR A 1 577 ? 215.872 187.052 146.945 1.00 70.33  ? 577 THR A C   1 
ATOM   4435  O  O   . THR A 1 577 ? 216.760 187.407 146.164 1.00 70.33  ? 577 THR A O   1 
ATOM   4436  C  CB  . THR A 1 577 ? 213.880 186.976 145.439 1.00 70.33  ? 577 THR A CB  1 
ATOM   4437  O  OG1 . THR A 1 577 ? 214.560 187.598 144.341 1.00 70.33  ? 577 THR A OG1 1 
ATOM   4438  C  CG2 . THR A 1 577 ? 212.390 187.263 145.333 1.00 70.33  ? 577 THR A CG2 1 
ATOM   4439  N  N   . GLY A 1 578 ? 216.101 186.267 147.987 1.00 62.86  ? 578 GLY A N   1 
ATOM   4440  C  CA  . GLY A 1 578 ? 217.457 185.888 148.315 1.00 62.86  ? 578 GLY A CA  1 
ATOM   4441  C  C   . GLY A 1 578 ? 217.500 184.913 149.466 1.00 62.86  ? 578 GLY A C   1 
ATOM   4442  O  O   . GLY A 1 578 ? 216.473 184.420 149.932 1.00 62.86  ? 578 GLY A O   1 
ATOM   4443  N  N   . GLU A 1 579 ? 218.719 184.659 149.928 1.00 64.58  ? 579 GLU A N   1 
ATOM   4444  C  CA  . GLU A 1 579 ? 219.004 183.606 150.890 1.00 64.58  ? 579 GLU A CA  1 
ATOM   4445  C  C   . GLU A 1 579 ? 218.915 184.158 152.314 1.00 64.58  ? 579 GLU A C   1 
ATOM   4446  O  O   . GLU A 1 579 ? 218.359 185.234 152.548 1.00 64.58  ? 579 GLU A O   1 
ATOM   4447  C  CB  . GLU A 1 579 ? 220.374 182.987 150.593 1.00 64.58  ? 579 GLU A CB  1 
ATOM   4448  C  CG  . GLU A 1 579 ? 220.526 182.419 149.186 1.00 64.58  ? 579 GLU A CG  1 
ATOM   4449  C  CD  . GLU A 1 579 ? 220.874 183.477 148.155 1.00 64.58  ? 579 GLU A CD  1 
ATOM   4450  O  OE1 . GLU A 1 579 ? 221.114 184.638 148.549 1.00 64.58  ? 579 GLU A OE1 1 
ATOM   4451  O  OE2 . GLU A 1 579 ? 220.906 183.147 146.951 1.00 64.58  ? 579 GLU A OE2 1 
ATOM   4452  N  N   . LEU A 1 580 ? 219.446 183.413 153.278 1.00 62.46  ? 580 LEU A N   1 
ATOM   4453  C  CA  . LEU A 1 580 ? 219.351 183.787 154.680 1.00 62.46  ? 580 LEU A CA  1 
ATOM   4454  C  C   . LEU A 1 580 ? 220.266 184.961 155.012 1.00 62.46  ? 580 LEU A C   1 
ATOM   4455  O  O   . LEU A 1 580 ? 221.351 185.117 154.446 1.00 62.46  ? 580 LEU A O   1 
ATOM   4456  C  CB  . LEU A 1 580 ? 219.704 182.597 155.573 1.00 62.46  ? 580 LEU A CB  1 
ATOM   4457  C  CG  . LEU A 1 580 ? 218.629 181.532 155.806 1.00 62.46  ? 580 LEU A CG  1 
ATOM   4458  C  CD1 . LEU A 1 580 ? 218.403 180.665 154.573 1.00 62.46  ? 580 LEU A CD1 1 
ATOM   4459  C  CD2 . LEU A 1 580 ? 218.985 180.678 157.010 1.00 62.46  ? 580 LEU A CD2 1 
ATOM   4460  N  N   . TYR A 1 581 ? 219.811 185.791 155.952 1.00 56.71  ? 581 TYR A N   1 
ATOM   4461  C  CA  . TYR A 1 581 ? 220.616 186.866 156.523 1.00 56.71  ? 581 TYR A CA  1 
ATOM   4462  C  C   . TYR A 1 581 ? 221.201 186.459 157.871 1.00 56.71  ? 581 TYR A C   1 
ATOM   4463  O  O   . TYR A 1 581 ? 222.422 186.459 158.058 1.00 56.71  ? 581 TYR A O   1 
ATOM   4464  C  CB  . TYR A 1 581 ? 219.759 188.136 156.654 1.00 56.71  ? 581 TYR A CB  1 
ATOM   4465  C  CG  . TYR A 1 581 ? 220.500 189.375 157.129 1.00 56.71  ? 581 TYR A CG  1 
ATOM   4466  C  CD1 . TYR A 1 581 ? 221.754 189.699 156.629 1.00 56.71  ? 581 TYR A CD1 1 
ATOM   4467  C  CD2 . TYR A 1 581 ? 219.933 190.232 158.063 1.00 56.71  ? 581 TYR A CD2 1 
ATOM   4468  C  CE1 . TYR A 1 581 ? 222.424 190.830 157.059 1.00 56.71  ? 581 TYR A CE1 1 
ATOM   4469  C  CE2 . TYR A 1 581 ? 220.595 191.362 158.493 1.00 56.71  ? 581 TYR A CE2 1 
ATOM   4470  C  CZ  . TYR A 1 581 ? 221.837 191.655 157.990 1.00 56.71  ? 581 TYR A CZ  1 
ATOM   4471  O  OH  . TYR A 1 581 ? 222.499 192.776 158.418 1.00 56.71  ? 581 TYR A OH  1 
ATOM   4472  N  N   . GLY A 1 582 ? 220.345 186.084 158.815 1.00 55.47  ? 582 GLY A N   1 
ATOM   4473  C  CA  . GLY A 1 582 ? 220.814 185.661 160.119 1.00 55.47  ? 582 GLY A CA  1 
ATOM   4474  C  C   . GLY A 1 582 ? 219.824 184.736 160.790 1.00 55.47  ? 582 GLY A C   1 
ATOM   4475  O  O   . GLY A 1 582 ? 218.674 184.595 160.372 1.00 55.47  ? 582 GLY A O   1 
ATOM   4476  N  N   . ILE A 1 583 ? 220.310 184.093 161.844 1.00 51.88  ? 583 ILE A N   1 
ATOM   4477  C  CA  . ILE A 1 583 ? 219.523 183.212 162.691 1.00 51.88  ? 583 ILE A CA  1 
ATOM   4478  C  C   . ILE A 1 583 ? 219.535 183.796 164.093 1.00 51.88  ? 583 ILE A C   1 
ATOM   4479  O  O   . ILE A 1 583 ? 220.602 184.113 164.631 1.00 51.88  ? 583 ILE A O   1 
ATOM   4480  C  CB  . ILE A 1 583 ? 220.075 181.779 162.690 1.00 51.88  ? 583 ILE A CB  1 
ATOM   4481  C  CG1 . ILE A 1 583 ? 220.023 181.197 161.282 1.00 51.88  ? 583 ILE A CG1 1 
ATOM   4482  C  CG2 . ILE A 1 583 ? 219.296 180.914 163.645 1.00 51.88  ? 583 ILE A CG2 1 
ATOM   4483  C  CD1 . ILE A 1 583 ? 218.650 181.240 160.666 1.00 51.88  ? 583 ILE A CD1 1 
ATOM   4484  N  N   . GLU A 1 584 ? 218.357 183.950 164.676 1.00 48.57  ? 584 GLU A N   1 
ATOM   4485  C  CA  . GLU A 1 584 ? 218.214 184.584 165.974 1.00 48.57  ? 584 GLU A CA  1 
ATOM   4486  C  C   . GLU A 1 584 ? 218.233 183.539 167.080 1.00 48.57  ? 584 GLU A C   1 
ATOM   4487  O  O   . GLU A 1 584 ? 218.061 182.343 166.847 1.00 48.57  ? 584 GLU A O   1 
ATOM   4488  C  CB  . GLU A 1 584 ? 216.922 185.395 166.025 1.00 48.57  ? 584 GLU A CB  1 
ATOM   4489  C  CG  . GLU A 1 584 ? 216.877 186.418 167.136 1.00 48.57  ? 584 GLU A CG  1 
ATOM   4490  C  CD  . GLU A 1 584 ? 215.641 187.289 167.076 1.00 48.57  ? 584 GLU A CD  1 
ATOM   4491  O  OE1 . GLU A 1 584 ? 214.791 187.057 166.190 1.00 48.57  ? 584 GLU A OE1 1 
ATOM   4492  O  OE2 . GLU A 1 584 ? 215.518 188.206 167.914 1.00 48.57  ? 584 GLU A OE2 1 
ATOM   4493  N  N   . ALA A 1 585 ? 218.451 184.008 168.299 1.00 43.84  ? 585 ALA A N   1 
ATOM   4494  C  CA  . ALA A 1 585 ? 218.427 183.161 169.477 1.00 43.84  ? 585 ALA A CA  1 
ATOM   4495  C  C   . ALA A 1 585 ? 217.424 183.706 170.481 1.00 43.84  ? 585 ALA A C   1 
ATOM   4496  O  O   . ALA A 1 585 ? 217.318 184.919 170.671 1.00 43.84  ? 585 ALA A O   1 
ATOM   4497  C  CB  . ALA A 1 585 ? 219.812 183.069 170.116 1.00 43.84  ? 585 ALA A CB  1 
ATOM   4498  N  N   . LEU A 1 586 ? 216.681 182.803 171.112 1.00 44.28  ? 586 LEU A N   1 
ATOM   4499  C  CA  . LEU A 1 586 ? 215.759 183.155 172.178 1.00 44.28  ? 586 LEU A CA  1 
ATOM   4500  C  C   . LEU A 1 586 ? 215.773 182.051 173.221 1.00 44.28  ? 586 LEU A C   1 
ATOM   4501  O  O   . LEU A 1 586 ? 215.791 180.867 172.877 1.00 44.28  ? 586 LEU A O   1 
ATOM   4502  C  CB  . LEU A 1 586 ? 214.333 183.355 171.651 1.00 44.28  ? 586 LEU A CB  1 
ATOM   4503  C  CG  . LEU A 1 586 ? 214.112 184.313 170.480 1.00 44.28  ? 586 LEU A CG  1 
ATOM   4504  C  CD1 . LEU A 1 586 ? 214.180 183.574 169.159 1.00 44.28  ? 586 LEU A CD1 1 
ATOM   4505  C  CD2 . LEU A 1 586 ? 212.781 185.030 170.627 1.00 44.28  ? 586 LEU A CD2 1 
ATOM   4506  N  N   . ALA A 1 587 ? 215.763 182.433 174.491 1.00 41.83  ? 587 ALA A N   1 
ATOM   4507  C  CA  . ALA A 1 587 ? 215.785 181.437 175.549 1.00 41.83  ? 587 ALA A CA  1 
ATOM   4508  C  C   . ALA A 1 587 ? 214.401 180.835 175.758 1.00 41.83  ? 587 ALA A C   1 
ATOM   4509  O  O   . ALA A 1 587 ? 213.388 181.538 175.769 1.00 41.83  ? 587 ALA A O   1 
ATOM   4510  C  CB  . ALA A 1 587 ? 216.289 182.056 176.847 1.00 41.83  ? 587 ALA A CB  1 
ATOM   4511  N  N   . ARG A 1 588 ? 214.365 179.515 175.933 1.00 42.28  ? 588 ARG A N   1 
ATOM   4512  C  CA  . ARG A 1 588 ? 213.114 178.792 176.113 1.00 42.28  ? 588 ARG A CA  1 
ATOM   4513  C  C   . ARG A 1 588 ? 213.255 177.825 177.277 1.00 42.28  ? 588 ARG A C   1 
ATOM   4514  O  O   . ARG A 1 588 ? 214.299 177.188 177.438 1.00 42.28  ? 588 ARG A O   1 
ATOM   4515  C  CB  . ARG A 1 588 ? 212.725 178.034 174.845 1.00 42.28  ? 588 ARG A CB  1 
ATOM   4516  C  CG  . ARG A 1 588 ? 212.398 178.924 173.673 1.00 42.28  ? 588 ARG A CG  1 
ATOM   4517  C  CD  . ARG A 1 588 ? 211.221 179.803 173.977 1.00 42.28  ? 588 ARG A CD  1 
ATOM   4518  N  NE  . ARG A 1 588 ? 210.384 179.991 172.801 1.00 42.28  ? 588 ARG A NE  1 
ATOM   4519  C  CZ  . ARG A 1 588 ? 210.374 181.084 172.054 1.00 42.28  ? 588 ARG A CZ  1 
ATOM   4520  N  NH1 . ARG A 1 588 ? 211.141 182.123 172.338 1.00 42.28  ? 588 ARG A NH1 1 
ATOM   4521  N  NH2 . ARG A 1 588 ? 209.569 181.140 170.997 1.00 42.28  ? 588 ARG A NH2 1 
ATOM   4522  N  N   . TRP A 1 589 ? 212.196 177.707 178.075 1.00 44.44  ? 589 TRP A N   1 
ATOM   4523  C  CA  . TRP A 1 589 ? 212.210 176.896 179.282 1.00 44.44  ? 589 TRP A CA  1 
ATOM   4524  C  C   . TRP A 1 589 ? 211.000 175.980 179.310 1.00 44.44  ? 589 TRP A C   1 
ATOM   4525  O  O   . TRP A 1 589 ? 209.918 176.355 178.849 1.00 44.44  ? 589 TRP A O   1 
ATOM   4526  C  CB  . TRP A 1 589 ? 212.212 177.766 180.526 1.00 44.44  ? 589 TRP A CB  1 
ATOM   4527  C  CG  . TRP A 1 589 ? 212.465 177.009 181.764 1.00 44.44  ? 589 TRP A CG  1 
ATOM   4528  C  CD1 . TRP A 1 589 ? 213.082 175.807 181.869 1.00 44.44  ? 589 TRP A CD1 1 
ATOM   4529  C  CD2 . TRP A 1 589 ? 212.122 177.402 183.092 1.00 44.44  ? 589 TRP A CD2 1 
ATOM   4530  N  NE1 . TRP A 1 589 ? 213.138 175.418 183.179 1.00 44.44  ? 589 TRP A NE1 1 
ATOM   4531  C  CE2 . TRP A 1 589 ? 212.560 176.388 183.950 1.00 44.44  ? 589 TRP A CE2 1 
ATOM   4532  C  CE3 . TRP A 1 589 ? 211.494 178.517 183.637 1.00 44.44  ? 589 TRP A CE3 1 
ATOM   4533  C  CZ2 . TRP A 1 589 ? 212.385 176.452 185.317 1.00 44.44  ? 589 TRP A CZ2 1 
ATOM   4534  C  CZ3 . TRP A 1 589 ? 211.322 178.576 184.985 1.00 44.44  ? 589 TRP A CZ3 1 
ATOM   4535  C  CH2 . TRP A 1 589 ? 211.761 177.552 185.813 1.00 44.44  ? 589 TRP A CH2 1 
ATOM   4536  N  N   . HIS A 1 590 ? 211.188 174.773 179.851 1.00 53.56  ? 590 HIS A N   1 
ATOM   4537  C  CA  . HIS A 1 590 ? 210.088 173.817 179.971 1.00 53.56  ? 590 HIS A CA  1 
ATOM   4538  C  C   . HIS A 1 590 ? 210.443 172.786 181.044 1.00 53.56  ? 590 HIS A C   1 
ATOM   4539  O  O   . HIS A 1 590 ? 211.310 171.938 180.820 1.00 53.56  ? 590 HIS A O   1 
ATOM   4540  C  CB  . HIS A 1 590 ? 209.801 173.154 178.636 1.00 53.56  ? 590 HIS A CB  1 
ATOM   4541  C  CG  . HIS A 1 590 ? 208.942 171.940 178.747 1.00 53.56  ? 590 HIS A CG  1 
ATOM   4542  N  ND1 . HIS A 1 590 ? 207.639 171.993 179.188 1.00 53.56  ? 590 HIS A ND1 1 
ATOM   4543  C  CD2 . HIS A 1 590 ? 209.196 170.641 178.471 1.00 53.56  ? 590 HIS A CD2 1 
ATOM   4544  C  CE1 . HIS A 1 590 ? 207.128 170.775 179.184 1.00 53.56  ? 590 HIS A CE1 1 
ATOM   4545  N  NE2 . HIS A 1 590 ? 208.052 169.936 178.753 1.00 53.56  ? 590 HIS A NE2 1 
ATOM   4546  N  N   . ASP A 1 591 ? 209.765 172.862 182.188 1.00 60.94  ? 591 ASP A N   1 
ATOM   4547  C  CA  . ASP A 1 591 ? 209.847 171.844 183.227 1.00 60.94  ? 591 ASP A CA  1 
ATOM   4548  C  C   . ASP A 1 591 ? 208.461 171.278 183.497 1.00 60.94  ? 591 ASP A C   1 
ATOM   4549  O  O   . ASP A 1 591 ? 207.505 172.047 183.668 1.00 60.94  ? 591 ASP A O   1 
ATOM   4550  C  CB  . ASP A 1 591 ? 210.437 172.398 184.529 1.00 60.94  ? 591 ASP A CB  1 
ATOM   4551  C  CG  . ASP A 1 591 ? 211.946 172.336 184.552 1.00 60.94  ? 591 ASP A CG  1 
ATOM   4552  O  OD1 . ASP A 1 591 ? 212.511 171.448 183.880 1.00 60.94  ? 591 ASP A OD1 1 
ATOM   4553  O  OD2 . ASP A 1 591 ? 212.571 173.167 185.244 1.00 60.94  ? 591 ASP A OD2 1 
ATOM   4554  N  N   . PRO A 1 592 ? 208.310 169.951 183.545 1.00 67.61  ? 592 PRO A N   1 
ATOM   4555  C  CA  . PRO A 1 592 ? 206.963 169.374 183.693 1.00 67.61  ? 592 PRO A CA  1 
ATOM   4556  C  C   . PRO A 1 592 ? 206.256 169.791 184.971 1.00 67.61  ? 592 PRO A C   1 
ATOM   4557  O  O   . PRO A 1 592 ? 205.028 169.931 184.976 1.00 67.61  ? 592 PRO A O   1 
ATOM   4558  C  CB  . PRO A 1 592 ? 207.229 167.862 183.654 1.00 67.61  ? 592 PRO A CB  1 
ATOM   4559  C  CG  . PRO A 1 592 ? 208.659 167.716 184.071 1.00 67.61  ? 592 PRO A CG  1 
ATOM   4560  C  CD  . PRO A 1 592 ? 209.365 168.925 183.541 1.00 67.61  ? 592 PRO A CD  1 
ATOM   4561  N  N   . LEU A 1 593 ? 206.999 169.995 186.059 1.00 64.40  ? 593 LEU A N   1 
ATOM   4562  C  CA  . LEU A 1 593 ? 206.367 170.379 187.314 1.00 64.40  ? 593 LEU A CA  1 
ATOM   4563  C  C   . LEU A 1 593 ? 205.754 171.767 187.229 1.00 64.40  ? 593 LEU A C   1 
ATOM   4564  O  O   . LEU A 1 593 ? 204.719 172.026 187.853 1.00 64.40  ? 593 LEU A O   1 
ATOM   4565  C  CB  . LEU A 1 593 ? 207.378 170.318 188.456 1.00 64.40  ? 593 LEU A CB  1 
ATOM   4566  C  CG  . LEU A 1 593 ? 206.827 170.602 189.853 1.00 64.40  ? 593 LEU A CG  1 
ATOM   4567  C  CD1 . LEU A 1 593 ? 205.769 169.577 190.228 1.00 64.40  ? 593 LEU A CD1 1 
ATOM   4568  C  CD2 . LEU A 1 593 ? 207.949 170.621 190.881 1.00 64.40  ? 593 LEU A CD2 1 
ATOM   4569  N  N   . HIS A 1 594 ? 206.367 172.669 186.466 1.00 60.02  ? 594 HIS A N   1 
ATOM   4570  C  CA  . HIS A 1 594 ? 205.879 174.030 186.358 1.00 60.02  ? 594 HIS A CA  1 
ATOM   4571  C  C   . HIS A 1 594 ? 205.373 174.394 184.978 1.00 60.02  ? 594 HIS A C   1 
ATOM   4572  O  O   . HIS A 1 594 ? 204.866 175.506 184.804 1.00 60.02  ? 594 HIS A O   1 
ATOM   4573  C  CB  . HIS A 1 594 ? 206.975 175.021 186.759 1.00 60.02  ? 594 HIS A CB  1 
ATOM   4574  C  CG  . HIS A 1 594 ? 207.189 175.108 188.234 1.00 60.02  ? 594 HIS A CG  1 
ATOM   4575  N  ND1 . HIS A 1 594 ? 206.434 175.926 189.047 1.00 60.02  ? 594 HIS A ND1 1 
ATOM   4576  C  CD2 . HIS A 1 594 ? 208.067 174.476 189.047 1.00 60.02  ? 594 HIS A CD2 1 
ATOM   4577  C  CE1 . HIS A 1 594 ? 206.842 175.797 190.296 1.00 60.02  ? 594 HIS A CE1 1 
ATOM   4578  N  NE2 . HIS A 1 594 ? 207.831 174.922 190.324 1.00 60.02  ? 594 HIS A NE2 1 
ATOM   4579  N  N   . GLY A 1 595 ? 205.494 173.509 184.001 1.00 59.26  ? 595 GLY A N   1 
ATOM   4580  C  CA  . GLY A 1 595 ? 205.000 173.773 182.668 1.00 59.26  ? 595 GLY A CA  1 
ATOM   4581  C  C   . GLY A 1 595 ? 206.029 174.437 181.775 1.00 59.26  ? 595 GLY A C   1 
ATOM   4582  O  O   . GLY A 1 595 ? 207.227 174.477 182.061 1.00 59.26  ? 595 GLY A O   1 
ATOM   4583  N  N   . HIS A 1 596 ? 205.535 174.966 180.663 1.00 50.96  ? 596 HIS A N   1 
ATOM   4584  C  CA  . HIS A 1 596 ? 206.375 175.653 179.685 1.00 50.96  ? 596 HIS A CA  1 
ATOM   4585  C  C   . HIS A 1 596 ? 206.365 177.159 179.943 1.00 50.96  ? 596 HIS A C   1 
ATOM   4586  O  O   . HIS A 1 596 ? 205.637 177.925 179.316 1.00 50.96  ? 596 HIS A O   1 
ATOM   4587  C  CB  . HIS A 1 596 ? 205.902 175.326 178.273 1.00 50.96  ? 596 HIS A CB  1 
ATOM   4588  C  CG  . HIS A 1 596 ? 206.725 175.956 177.196 1.00 50.96  ? 596 HIS A CG  1 
ATOM   4589  N  ND1 . HIS A 1 596 ? 207.995 175.522 176.878 1.00 50.96  ? 596 HIS A ND1 1 
ATOM   4590  C  CD2 . HIS A 1 596 ? 206.457 176.983 176.355 1.00 50.96  ? 596 HIS A CD2 1 
ATOM   4591  C  CE1 . HIS A 1 596 ? 208.474 176.259 175.891 1.00 50.96  ? 596 HIS A CE1 1 
ATOM   4592  N  NE2 . HIS A 1 596 ? 207.561 177.152 175.556 1.00 50.96  ? 596 HIS A NE2 1 
ATOM   4593  N  N   . VAL A 1 597 ? 207.191 177.571 180.898 1.00 48.25  ? 597 VAL A N   1 
ATOM   4594  C  CA  . VAL A 1 597 ? 207.253 178.988 181.269 1.00 48.25  ? 597 VAL A CA  1 
ATOM   4595  C  C   . VAL A 1 597 ? 207.773 179.793 180.089 1.00 48.25  ? 597 VAL A C   1 
ATOM   4596  O  O   . VAL A 1 597 ? 208.777 179.401 179.467 1.00 48.25  ? 597 VAL A O   1 
ATOM   4597  C  CB  . VAL A 1 597 ? 208.147 179.180 182.501 1.00 48.25  ? 597 VAL A CB  1 
ATOM   4598  C  CG1 . VAL A 1 597 ? 208.214 180.643 182.886 1.00 48.25  ? 597 VAL A CG1 1 
ATOM   4599  C  CG2 . VAL A 1 597 ? 207.635 178.339 183.658 1.00 48.25  ? 597 VAL A CG2 1 
ATOM   4600  N  N   . PRO A 1 598 ? 207.135 180.893 179.721 1.00 49.07  ? 598 PRO A N   1 
ATOM   4601  C  CA  . PRO A 1 598 ? 207.582 181.657 178.567 1.00 49.07  ? 598 PRO A CA  1 
ATOM   4602  C  C   . PRO A 1 598 ? 208.551 182.752 178.973 1.00 49.07  ? 598 PRO A C   1 
ATOM   4603  O  O   . PRO A 1 598 ? 208.689 183.070 180.169 1.00 49.07  ? 598 PRO A O   1 
ATOM   4604  C  CB  . PRO A 1 598 ? 206.275 182.239 178.012 1.00 49.07  ? 598 PRO A CB  1 
ATOM   4605  C  CG  . PRO A 1 598 ? 205.371 182.341 179.196 1.00 49.07  ? 598 PRO A CG  1 
ATOM   4606  C  CD  . PRO A 1 598 ? 205.856 181.384 180.255 1.00 49.07  ? 598 PRO A CD  1 
ATOM   4607  N  N   . PRO A 1 599 ? 209.255 183.346 178.002 1.00 47.97  ? 599 PRO A N   1 
ATOM   4608  C  CA  . PRO A 1 599 ? 210.227 184.395 178.345 1.00 47.97  ? 599 PRO A CA  1 
ATOM   4609  C  C   . PRO A 1 599 ? 209.616 185.566 179.083 1.00 47.97  ? 599 PRO A C   1 
ATOM   4610  O  O   . PRO A 1 599 ? 210.216 186.070 180.043 1.00 47.97  ? 599 PRO A O   1 
ATOM   4611  C  CB  . PRO A 1 599 ? 210.783 184.812 176.978 1.00 47.97  ? 599 PRO A CB  1 
ATOM   4612  C  CG  . PRO A 1 599 ? 210.544 183.648 176.103 1.00 47.97  ? 599 PRO A CG  1 
ATOM   4613  C  CD  . PRO A 1 599 ? 209.265 183.039 176.564 1.00 47.97  ? 599 PRO A CD  1 
ATOM   4614  N  N   . SER A 1 600 ? 208.419 185.990 178.684 1.00 51.42  ? 600 SER A N   1 
ATOM   4615  C  CA  . SER A 1 600 ? 207.773 187.106 179.358 1.00 51.42  ? 600 SER A CA  1 
ATOM   4616  C  C   . SER A 1 600 ? 207.537 186.804 180.826 1.00 51.42  ? 600 SER A C   1 
ATOM   4617  O  O   . SER A 1 600 ? 207.386 187.726 181.633 1.00 51.42  ? 600 SER A O   1 
ATOM   4618  C  CB  . SER A 1 600 ? 206.452 187.443 178.671 1.00 51.42  ? 600 SER A CB  1 
ATOM   4619  O  OG  . SER A 1 600 ? 205.478 186.451 178.940 1.00 51.42  ? 600 SER A OG  1 
ATOM   4620  N  N   . ARG A 1 601 ? 207.505 185.528 181.193 1.00 54.29  ? 601 ARG A N   1 
ATOM   4621  C  CA  . ARG A 1 601 ? 207.317 185.181 182.592 1.00 54.29  ? 601 ARG A CA  1 
ATOM   4622  C  C   . ARG A 1 601 ? 208.636 184.993 183.325 1.00 54.29  ? 601 ARG A C   1 
ATOM   4623  O  O   . ARG A 1 601 ? 208.741 185.365 184.497 1.00 54.29  ? 601 ARG A O   1 
ATOM   4624  C  CB  . ARG A 1 601 ? 206.469 183.913 182.716 1.00 54.29  ? 601 ARG A CB  1 
ATOM   4625  C  CG  . ARG A 1 601 ? 206.030 183.605 184.139 1.00 54.29  ? 601 ARG A CG  1 
ATOM   4626  C  CD  . ARG A 1 601 ? 204.934 182.553 184.174 1.00 54.29  ? 601 ARG A CD  1 
ATOM   4627  N  NE  . ARG A 1 601 ? 204.509 182.261 185.538 1.00 54.29  ? 601 ARG A NE  1 
ATOM   4628  C  CZ  . ARG A 1 601 ? 203.630 181.324 185.866 1.00 54.29  ? 601 ARG A CZ  1 
ATOM   4629  N  NH1 . ARG A 1 601 ? 203.059 180.561 184.948 1.00 54.29  ? 601 ARG A NH1 1 
ATOM   4630  N  NH2 . ARG A 1 601 ? 203.317 181.148 187.146 1.00 54.29  ? 601 ARG A NH2 1 
ATOM   4631  N  N   . PHE A 1 602 ? 209.649 184.419 182.679 1.00 48.45  ? 602 PHE A N   1 
ATOM   4632  C  CA  . PHE A 1 602 ? 210.835 184.031 183.432 1.00 48.45  ? 602 PHE A CA  1 
ATOM   4633  C  C   . PHE A 1 602 ? 212.015 184.985 183.286 1.00 48.45  ? 602 PHE A C   1 
ATOM   4634  O  O   . PHE A 1 602 ? 213.018 184.795 183.978 1.00 48.45  ? 602 PHE A O   1 
ATOM   4635  C  CB  . PHE A 1 602 ? 211.252 182.594 183.075 1.00 48.45  ? 602 PHE A CB  1 
ATOM   4636  C  CG  . PHE A 1 602 ? 212.112 182.468 181.854 1.00 48.45  ? 602 PHE A CG  1 
ATOM   4637  C  CD1 . PHE A 1 602 ? 213.474 182.600 181.933 1.00 48.45  ? 602 PHE A CD1 1 
ATOM   4638  C  CD2 . PHE A 1 602 ? 211.555 182.164 180.636 1.00 48.45  ? 602 PHE A CD2 1 
ATOM   4639  C  CE1 . PHE A 1 602 ? 214.251 182.470 180.822 1.00 48.45  ? 602 PHE A CE1 1 
ATOM   4640  C  CE2 . PHE A 1 602 ? 212.342 182.029 179.522 1.00 48.45  ? 602 PHE A CE2 1 
ATOM   4641  C  CZ  . PHE A 1 602 ? 213.685 182.187 179.618 1.00 48.45  ? 602 PHE A CZ  1 
ATOM   4642  N  N   . ILE A 1 603 ? 211.935 186.010 182.440 1.00 52.03  ? 603 ILE A N   1 
ATOM   4643  C  CA  . ILE A 1 603 ? 213.029 186.984 182.395 1.00 52.03  ? 603 ILE A CA  1 
ATOM   4644  C  C   . ILE A 1 603 ? 212.915 187.977 183.550 1.00 52.03  ? 603 ILE A C   1 
ATOM   4645  O  O   . ILE A 1 603 ? 213.904 188.176 184.273 1.00 52.03  ? 603 ILE A O   1 
ATOM   4646  C  CB  . ILE A 1 603 ? 213.100 187.698 181.038 1.00 52.03  ? 603 ILE A CB  1 
ATOM   4647  C  CG1 . ILE A 1 603 ? 213.388 186.689 179.931 1.00 52.03  ? 603 ILE A CG1 1 
ATOM   4648  C  CG2 . ILE A 1 603 ? 214.185 188.743 181.063 1.00 52.03  ? 603 ILE A CG2 1 
ATOM   4649  C  CD1 . ILE A 1 603 ? 214.737 186.035 180.053 1.00 52.03  ? 603 ILE A CD1 1 
ATOM   4650  N  N   . PRO A 1 604 ? 211.768 188.640 183.767 1.00 54.08  ? 604 PRO A N   1 
ATOM   4651  C  CA  . PRO A 1 604 ? 211.659 189.493 184.963 1.00 54.08  ? 604 PRO A CA  1 
ATOM   4652  C  C   . PRO A 1 604 ? 211.859 188.736 186.262 1.00 54.08  ? 604 PRO A C   1 
ATOM   4653  O  O   . PRO A 1 604 ? 212.433 189.282 187.212 1.00 54.08  ? 604 PRO A O   1 
ATOM   4654  C  CB  . PRO A 1 604 ? 210.244 190.074 184.852 1.00 54.08  ? 604 PRO A CB  1 
ATOM   4655  C  CG  . PRO A 1 604 ? 209.527 189.167 183.932 1.00 54.08  ? 604 PRO A CG  1 
ATOM   4656  C  CD  . PRO A 1 604 ? 210.545 188.717 182.952 1.00 54.08  ? 604 PRO A CD  1 
ATOM   4657  N  N   . LEU A 1 605 ? 211.408 187.483 186.331 1.00 57.88  ? 605 LEU A N   1 
ATOM   4658  C  CA  . LEU A 1 605 ? 211.737 186.648 187.480 1.00 57.88  ? 605 LEU A CA  1 
ATOM   4659  C  C   . LEU A 1 605 ? 213.237 186.433 187.578 1.00 57.88  ? 605 LEU A C   1 
ATOM   4660  O  O   . LEU A 1 605 ? 213.800 186.420 188.678 1.00 57.88  ? 605 LEU A O   1 
ATOM   4661  C  CB  . LEU A 1 605 ? 211.017 185.304 187.384 1.00 57.88  ? 605 LEU A CB  1 
ATOM   4662  C  CG  . LEU A 1 605 ? 211.622 184.128 188.156 1.00 57.88  ? 605 LEU A CG  1 
ATOM   4663  C  CD1 . LEU A 1 605 ? 211.554 184.354 189.653 1.00 57.88  ? 605 LEU A CD1 1 
ATOM   4664  C  CD2 . LEU A 1 605 ? 210.919 182.838 187.784 1.00 57.88  ? 605 LEU A CD2 1 
ATOM   4665  N  N   . ALA A 1 606 ? 213.899 186.239 186.438 1.00 58.80  ? 606 ALA A N   1 
ATOM   4666  C  CA  . ALA A 1 606 ? 215.341 186.046 186.459 1.00 58.80  ? 606 ALA A CA  1 
ATOM   4667  C  C   . ALA A 1 606 ? 216.034 187.264 187.042 1.00 58.80  ? 606 ALA A C   1 
ATOM   4668  O  O   . ALA A 1 606 ? 216.992 187.138 187.814 1.00 58.80  ? 606 ALA A O   1 
ATOM   4669  C  CB  . ALA A 1 606 ? 215.859 185.753 185.051 1.00 58.80  ? 606 ALA A CB  1 
ATOM   4670  N  N   . GLU A 1 607 ? 215.562 188.457 186.684 1.00 62.26  ? 607 GLU A N   1 
ATOM   4671  C  CA  . GLU A 1 607 ? 216.118 189.674 187.263 1.00 62.26  ? 607 GLU A CA  1 
ATOM   4672  C  C   . GLU A 1 607 ? 215.833 189.749 188.757 1.00 62.26  ? 607 GLU A C   1 
ATOM   4673  O  O   . GLU A 1 607 ? 216.723 190.055 189.557 1.00 62.26  ? 607 GLU A O   1 
ATOM   4674  C  CB  . GLU A 1 607 ? 215.558 190.900 186.540 1.00 62.26  ? 607 GLU A CB  1 
ATOM   4675  C  CG  . GLU A 1 607 ? 215.903 192.227 187.195 1.00 62.26  ? 607 GLU A CG  1 
ATOM   4676  C  CD  . GLU A 1 607 ? 214.813 192.721 188.125 1.00 62.26  ? 607 GLU A CD  1 
ATOM   4677  O  OE1 . GLU A 1 607 ? 213.646 192.795 187.686 1.00 62.26  ? 607 GLU A OE1 1 
ATOM   4678  O  OE2 . GLU A 1 607 ? 215.122 193.035 189.293 1.00 62.26  ? 607 GLU A OE2 1 
ATOM   4679  N  N   . GLU A 1 608 ? 214.592 189.466 189.152 1.00 63.38  ? 608 GLU A N   1 
ATOM   4680  C  CA  . GLU A 1 608 ? 214.200 189.644 190.546 1.00 63.38  ? 608 GLU A CA  1 
ATOM   4681  C  C   . GLU A 1 608 ? 214.965 188.702 191.467 1.00 63.38  ? 608 GLU A C   1 
ATOM   4682  O  O   . GLU A 1 608 ? 215.435 189.105 192.536 1.00 63.38  ? 608 GLU A O   1 
ATOM   4683  C  CB  . GLU A 1 608 ? 212.692 189.436 190.694 1.00 63.38  ? 608 GLU A CB  1 
ATOM   4684  C  CG  . GLU A 1 608 ? 212.182 189.581 192.119 1.00 63.38  ? 608 GLU A CG  1 
ATOM   4685  C  CD  . GLU A 1 608 ? 210.683 189.383 192.226 1.00 63.38  ? 608 GLU A CD  1 
ATOM   4686  O  OE1 . GLU A 1 608 ? 209.943 190.003 191.434 1.00 63.38  ? 608 GLU A OE1 1 
ATOM   4687  O  OE2 . GLU A 1 608 ? 210.245 188.608 193.101 1.00 63.38  ? 608 GLU A OE2 1 
ATOM   4688  N  N   . ILE A 1 609 ? 215.106 187.439 191.064 1.00 62.63  ? 609 ILE A N   1 
ATOM   4689  C  CA  . ILE A 1 609 ? 215.718 186.438 191.928 1.00 62.63  ? 609 ILE A CA  1 
ATOM   4690  C  C   . ILE A 1 609 ? 217.194 186.695 192.175 1.00 62.63  ? 609 ILE A C   1 
ATOM   4691  O  O   . ILE A 1 609 ? 217.719 186.280 193.213 1.00 62.63  ? 609 ILE A O   1 
ATOM   4692  C  CB  . ILE A 1 609 ? 215.504 185.026 191.345 1.00 62.63  ? 609 ILE A CB  1 
ATOM   4693  C  CG1 . ILE A 1 609 ? 215.779 183.962 192.408 1.00 62.63  ? 609 ILE A CG1 1 
ATOM   4694  C  CG2 . ILE A 1 609 ? 216.363 184.807 190.107 1.00 62.63  ? 609 ILE A CG2 1 
ATOM   4695  C  CD1 . ILE A 1 609 ? 214.818 184.006 193.574 1.00 62.63  ? 609 ILE A CD1 1 
ATOM   4696  N  N   . GLY A 1 610 ? 217.874 187.382 191.264 1.00 64.18  ? 610 GLY A N   1 
ATOM   4697  C  CA  . GLY A 1 610 ? 219.272 187.704 191.462 1.00 64.18  ? 610 GLY A CA  1 
ATOM   4698  C  C   . GLY A 1 610 ? 220.217 186.779 190.730 1.00 64.18  ? 610 GLY A C   1 
ATOM   4699  O  O   . GLY A 1 610 ? 221.413 186.737 191.033 1.00 64.18  ? 610 GLY A O   1 
ATOM   4700  N  N   . GLU A 1 611 ? 219.696 186.029 189.761 1.00 64.16  ? 611 GLU A N   1 
ATOM   4701  C  CA  . GLU A 1 611 ? 220.513 185.101 188.989 1.00 64.16  ? 611 GLU A CA  1 
ATOM   4702  C  C   . GLU A 1 611 ? 220.543 185.468 187.512 1.00 64.16  ? 611 GLU A C   1 
ATOM   4703  O  O   . GLU A 1 611 ? 220.626 184.578 186.660 1.00 64.16  ? 611 GLU A O   1 
ATOM   4704  C  CB  . GLU A 1 611 ? 220.014 183.667 189.169 1.00 64.16  ? 611 GLU A CB  1 
ATOM   4705  C  CG  . GLU A 1 611 ? 220.609 182.955 190.372 1.00 64.16  ? 611 GLU A CG  1 
ATOM   4706  C  CD  . GLU A 1 611 ? 220.183 183.575 191.689 1.00 64.16  ? 611 GLU A CD  1 
ATOM   4707  O  OE1 . GLU A 1 611 ? 219.069 184.136 191.752 1.00 64.16  ? 611 GLU A OE1 1 
ATOM   4708  O  OE2 . GLU A 1 611 ? 220.963 183.499 192.662 1.00 64.16  ? 611 GLU A OE2 1 
ATOM   4709  N  N   . ILE A 1 612 ? 220.487 186.761 187.190 1.00 60.71  ? 612 ILE A N   1 
ATOM   4710  C  CA  . ILE A 1 612 ? 220.426 187.177 185.792 1.00 60.71  ? 612 ILE A CA  1 
ATOM   4711  C  C   . ILE A 1 612 ? 221.745 186.919 185.078 1.00 60.71  ? 612 ILE A C   1 
ATOM   4712  O  O   . ILE A 1 612 ? 221.764 186.636 183.874 1.00 60.71  ? 612 ILE A O   1 
ATOM   4713  C  CB  . ILE A 1 612 ? 219.999 188.656 185.701 1.00 60.71  ? 612 ILE A CB  1 
ATOM   4714  C  CG1 . ILE A 1 612 ? 219.610 189.004 184.268 1.00 60.71  ? 612 ILE A CG1 1 
ATOM   4715  C  CG2 . ILE A 1 612 ? 221.092 189.574 186.216 1.00 60.71  ? 612 ILE A CG2 1 
ATOM   4716  C  CD1 . ILE A 1 612 ? 218.398 188.245 183.775 1.00 60.71  ? 612 ILE A CD1 1 
ATOM   4717  N  N   . GLU A 1 613 ? 222.864 187.000 185.797 1.00 66.59  ? 613 GLU A N   1 
ATOM   4718  C  CA  . GLU A 1 613 ? 224.161 186.834 185.153 1.00 66.59  ? 613 GLU A CA  1 
ATOM   4719  C  C   . GLU A 1 613 ? 224.335 185.421 184.620 1.00 66.59  ? 613 GLU A C   1 
ATOM   4720  O  O   . GLU A 1 613 ? 224.983 185.214 183.587 1.00 66.59  ? 613 GLU A O   1 
ATOM   4721  C  CB  . GLU A 1 613 ? 225.282 187.181 186.132 1.00 66.59  ? 613 GLU A CB  1 
ATOM   4722  C  CG  . GLU A 1 613 ? 225.063 188.477 186.898 1.00 66.59  ? 613 GLU A CG  1 
ATOM   4723  C  CD  . GLU A 1 613 ? 225.472 189.708 186.108 1.00 66.59  ? 613 GLU A CD  1 
ATOM   4724  O  OE1 . GLU A 1 613 ? 225.730 189.584 184.892 1.00 66.59  ? 613 GLU A OE1 1 
ATOM   4725  O  OE2 . GLU A 1 613 ? 225.534 190.802 186.706 1.00 66.59  ? 613 GLU A OE2 1 
ATOM   4726  N  N   . ASN A 1 614 ? 223.773 184.434 185.315 1.00 64.74  ? 614 ASN A N   1 
ATOM   4727  C  CA  . ASN A 1 614 ? 223.935 183.052 184.884 1.00 64.74  ? 614 ASN A CA  1 
ATOM   4728  C  C   . ASN A 1 614 ? 223.291 182.827 183.523 1.00 64.74  ? 614 ASN A C   1 
ATOM   4729  O  O   . ASN A 1 614 ? 223.927 182.300 182.600 1.00 64.74  ? 614 ASN A O   1 
ATOM   4730  C  CB  . ASN A 1 614 ? 223.350 182.112 185.931 1.00 64.74  ? 614 ASN A CB  1 
ATOM   4731  C  CG  . ASN A 1 614 ? 224.116 182.150 187.232 1.00 64.74  ? 614 ASN A CG  1 
ATOM   4732  O  OD1 . ASN A 1 614 ? 225.345 182.208 187.237 1.00 64.74  ? 614 ASN A OD1 1 
ATOM   4733  N  ND2 . ASN A 1 614 ? 223.395 182.120 188.346 1.00 64.74  ? 614 ASN A ND2 1 
ATOM   4734  N  N   . ILE A 1 615 ? 222.032 183.241 183.370 1.00 62.44  ? 615 ILE A N   1 
ATOM   4735  C  CA  . ILE A 1 615 ? 221.375 183.112 182.074 1.00 62.44  ? 615 ILE A CA  1 
ATOM   4736  C  C   . ILE A 1 615 ? 222.066 183.996 181.046 1.00 62.44  ? 615 ILE A C   1 
ATOM   4737  O  O   . ILE A 1 615 ? 222.188 183.627 179.870 1.00 62.44  ? 615 ILE A O   1 
ATOM   4738  C  CB  . ILE A 1 615 ? 219.868 183.422 182.189 1.00 62.44  ? 615 ILE A CB  1 
ATOM   4739  C  CG1 . ILE A 1 615 ? 219.209 183.378 180.817 1.00 62.44  ? 615 ILE A CG1 1 
ATOM   4740  C  CG2 . ILE A 1 615 ? 219.626 184.759 182.828 1.00 62.44  ? 615 ILE A CG2 1 
ATOM   4741  C  CD1 . ILE A 1 615 ? 217.742 183.068 180.874 1.00 62.44  ? 615 ILE A CD1 1 
ATOM   4742  N  N   . GLY A 1 616 ? 222.560 185.160 181.476 1.00 63.66  ? 616 GLY A N   1 
ATOM   4743  C  CA  . GLY A 1 616 ? 223.240 186.044 180.548 1.00 63.66  ? 616 GLY A CA  1 
ATOM   4744  C  C   . GLY A 1 616 ? 224.469 185.413 179.926 1.00 63.66  ? 616 GLY A C   1 
ATOM   4745  O  O   . GLY A 1 616 ? 224.710 185.552 178.725 1.00 63.66  ? 616 GLY A O   1 
ATOM   4746  N  N   . ARG A 1 617 ? 225.269 184.719 180.731 1.00 63.55  ? 617 ARG A N   1 
ATOM   4747  C  CA  . ARG A 1 617 ? 226.444 184.062 180.173 1.00 63.55  ? 617 ARG A CA  1 
ATOM   4748  C  C   . ARG A 1 617 ? 226.076 182.786 179.433 1.00 63.55  ? 617 ARG A C   1 
ATOM   4749  O  O   . ARG A 1 617 ? 226.719 182.447 178.429 1.00 63.55  ? 617 ARG A O   1 
ATOM   4750  C  CB  . ARG A 1 617 ? 227.471 183.774 181.273 1.00 63.55  ? 617 ARG A CB  1 
ATOM   4751  C  CG  . ARG A 1 617 ? 227.034 182.765 182.321 1.00 63.55  ? 617 ARG A CG  1 
ATOM   4752  C  CD  . ARG A 1 617 ? 228.109 182.574 183.378 1.00 63.55  ? 617 ARG A CD  1 
ATOM   4753  N  NE  . ARG A 1 617 ? 227.649 181.738 184.480 1.00 63.55  ? 617 ARG A NE  1 
ATOM   4754  C  CZ  . ARG A 1 617 ? 227.948 180.454 184.623 1.00 63.55  ? 617 ARG A CZ  1 
ATOM   4755  N  NH1 . ARG A 1 617 ? 228.708 179.820 183.745 1.00 63.55  ? 617 ARG A NH1 1 
ATOM   4756  N  NH2 . ARG A 1 617 ? 227.472 179.789 185.672 1.00 63.55  ? 617 ARG A NH2 1 
ATOM   4757  N  N   . TRP A 1 618 ? 225.042 182.084 179.896 1.00 55.15  ? 618 TRP A N   1 
ATOM   4758  C  CA  . TRP A 1 618 ? 224.666 180.827 179.264 1.00 55.15  ? 618 TRP A CA  1 
ATOM   4759  C  C   . TRP A 1 618 ? 224.143 181.045 177.853 1.00 55.15  ? 618 TRP A C   1 
ATOM   4760  O  O   . TRP A 1 618 ? 224.442 180.258 176.944 1.00 55.15  ? 618 TRP A O   1 
ATOM   4761  C  CB  . TRP A 1 618 ? 223.621 180.114 180.116 1.00 55.15  ? 618 TRP A CB  1 
ATOM   4762  C  CG  . TRP A 1 618 ? 223.308 178.748 179.624 1.00 55.15  ? 618 TRP A CG  1 
ATOM   4763  C  CD1 . TRP A 1 618 ? 223.845 177.578 180.064 1.00 55.15  ? 618 TRP A CD1 1 
ATOM   4764  C  CD2 . TRP A 1 618 ? 222.395 178.403 178.581 1.00 55.15  ? 618 TRP A CD2 1 
ATOM   4765  N  NE1 . TRP A 1 618 ? 223.317 176.524 179.366 1.00 55.15  ? 618 TRP A NE1 1 
ATOM   4766  C  CE2 . TRP A 1 618 ? 222.423 177.008 178.449 1.00 55.15  ? 618 TRP A CE2 1 
ATOM   4767  C  CE3 . TRP A 1 618 ? 221.549 179.138 177.754 1.00 55.15  ? 618 TRP A CE3 1 
ATOM   4768  C  CZ2 . TRP A 1 618 ? 221.644 176.336 177.522 1.00 55.15  ? 618 TRP A CZ2 1 
ATOM   4769  C  CZ3 . TRP A 1 618 ? 220.781 178.471 176.838 1.00 55.15  ? 618 TRP A CZ3 1 
ATOM   4770  C  CH2 . TRP A 1 618 ? 220.830 177.085 176.727 1.00 55.15  ? 618 TRP A CH2 1 
ATOM   4771  N  N   . VAL A 1 619 ? 223.359 182.106 177.649 1.00 55.19  ? 619 VAL A N   1 
ATOM   4772  C  CA  . VAL A 1 619 ? 222.689 182.296 176.368 1.00 55.19  ? 619 VAL A CA  1 
ATOM   4773  C  C   . VAL A 1 619 ? 223.699 182.468 175.247 1.00 55.19  ? 619 VAL A C   1 
ATOM   4774  O  O   . VAL A 1 619 ? 223.386 182.223 174.076 1.00 55.19  ? 619 VAL A O   1 
ATOM   4775  C  CB  . VAL A 1 619 ? 221.723 183.491 176.453 1.00 55.19  ? 619 VAL A CB  1 
ATOM   4776  C  CG1 . VAL A 1 619 ? 222.494 184.780 176.602 1.00 55.19  ? 619 VAL A CG1 1 
ATOM   4777  C  CG2 . VAL A 1 619 ? 220.811 183.539 175.239 1.00 55.19  ? 619 VAL A CG2 1 
ATOM   4778  N  N   . ILE A 1 620 ? 224.921 182.877 175.574 1.00 61.02  ? 620 ILE A N   1 
ATOM   4779  C  CA  . ILE A 1 620 ? 225.935 183.120 174.555 1.00 61.02  ? 620 ILE A CA  1 
ATOM   4780  C  C   . ILE A 1 620 ? 226.948 181.984 174.538 1.00 61.02  ? 620 ILE A C   1 
ATOM   4781  O  O   . ILE A 1 620 ? 227.516 181.669 173.486 1.00 61.02  ? 620 ILE A O   1 
ATOM   4782  C  CB  . ILE A 1 620 ? 226.619 184.484 174.765 1.00 61.02  ? 620 ILE A CB  1 
ATOM   4783  C  CG1 . ILE A 1 620 ? 227.528 184.813 173.582 1.00 61.02  ? 620 ILE A CG1 1 
ATOM   4784  C  CG2 . ILE A 1 620 ? 227.396 184.517 176.072 1.00 61.02  ? 620 ILE A CG2 1 
ATOM   4785  C  CD1 . ILE A 1 620 ? 227.908 186.266 173.499 1.00 61.02  ? 620 ILE A CD1 1 
ATOM   4786  N  N   . ALA A 1 621 ? 227.191 181.354 175.692 1.00 58.86  ? 621 ALA A N   1 
ATOM   4787  C  CA  . ALA A 1 621 ? 228.051 180.175 175.690 1.00 58.86  ? 621 ALA A CA  1 
ATOM   4788  C  C   . ALA A 1 621 ? 227.451 179.082 174.821 1.00 58.86  ? 621 ALA A C   1 
ATOM   4789  O  O   . ALA A 1 621 ? 228.129 178.498 173.960 1.00 58.86  ? 621 ALA A O   1 
ATOM   4790  C  CB  . ALA A 1 621 ? 228.265 179.678 177.117 1.00 58.86  ? 621 ALA A CB  1 
ATOM   4791  N  N   . GLU A 1 622 ? 226.162 178.809 175.021 1.00 63.06  ? 622 GLU A N   1 
ATOM   4792  C  CA  . GLU A 1 622 ? 225.479 177.853 174.164 1.00 63.06  ? 622 GLU A CA  1 
ATOM   4793  C  C   . GLU A 1 622 ? 225.488 178.327 172.720 1.00 63.06  ? 622 GLU A C   1 
ATOM   4794  O  O   . GLU A 1 622 ? 225.547 177.514 171.795 1.00 63.06  ? 622 GLU A O   1 
ATOM   4795  C  CB  . GLU A 1 622 ? 224.048 177.637 174.657 1.00 63.06  ? 622 GLU A CB  1 
ATOM   4796  C  CG  . GLU A 1 622 ? 223.286 176.550 173.916 1.00 63.06  ? 622 GLU A CG  1 
ATOM   4797  C  CD  . GLU A 1 622 ? 223.748 175.155 174.295 1.00 63.06  ? 622 GLU A CD  1 
ATOM   4798  O  OE1 . GLU A 1 622 ? 224.297 174.990 175.405 1.00 63.06  ? 622 GLU A OE1 1 
ATOM   4799  O  OE2 . GLU A 1 622 ? 223.561 174.224 173.484 1.00 63.06  ? 622 GLU A OE2 1 
ATOM   4800  N  N   . ALA A 1 623 ? 225.455 179.642 172.509 1.00 60.17  ? 623 ALA A N   1 
ATOM   4801  C  CA  . ALA A 1 623 ? 225.467 180.167 171.150 1.00 60.17  ? 623 ALA A CA  1 
ATOM   4802  C  C   . ALA A 1 623 ? 226.758 179.803 170.439 1.00 60.17  ? 623 ALA A C   1 
ATOM   4803  O  O   . ALA A 1 623 ? 226.743 179.283 169.317 1.00 60.17  ? 623 ALA A O   1 
ATOM   4804  C  CB  . ALA A 1 623 ? 225.281 181.681 171.174 1.00 60.17  ? 623 ALA A CB  1 
ATOM   4805  N  N   . CYS A 1 624 ? 227.890 180.072 171.085 1.00 67.79  ? 624 CYS A N   1 
ATOM   4806  C  CA  . CYS A 1 624 ? 229.181 179.766 170.477 1.00 67.79  ? 624 CYS A CA  1 
ATOM   4807  C  C   . CYS A 1 624 ? 229.328 178.269 170.234 1.00 67.79  ? 624 CYS A C   1 
ATOM   4808  O  O   . CYS A 1 624 ? 229.763 177.839 169.155 1.00 67.79  ? 624 CYS A O   1 
ATOM   4809  C  CB  . CYS A 1 624 ? 230.315 180.288 171.360 1.00 67.79  ? 624 CYS A CB  1 
ATOM   4810  S  SG  . CYS A 1 624 ? 230.348 182.086 171.544 1.00 67.79  ? 624 CYS A SG  1 
ATOM   4811  N  N   . ARG A 1 625 ? 228.946 177.455 171.219 1.00 63.15  ? 625 ARG A N   1 
ATOM   4812  C  CA  . ARG A 1 625 ? 229.051 176.014 171.025 1.00 63.15  ? 625 ARG A CA  1 
ATOM   4813  C  C   . ARG A 1 625 ? 228.184 175.553 169.861 1.00 63.15  ? 625 ARG A C   1 
ATOM   4814  O  O   . ARG A 1 625 ? 228.602 174.708 169.060 1.00 63.15  ? 625 ARG A O   1 
ATOM   4815  C  CB  . ARG A 1 625 ? 228.667 175.280 172.308 1.00 63.15  ? 625 ARG A CB  1 
ATOM   4816  C  CG  . ARG A 1 625 ? 228.987 173.796 172.288 1.00 63.15  ? 625 ARG A CG  1 
ATOM   4817  C  CD  . ARG A 1 625 ? 227.756 172.971 171.962 1.00 63.15  ? 625 ARG A CD  1 
ATOM   4818  N  NE  . ARG A 1 625 ? 226.877 172.818 173.114 1.00 63.15  ? 625 ARG A NE  1 
ATOM   4819  C  CZ  . ARG A 1 625 ? 225.790 172.059 173.128 1.00 63.15  ? 625 ARG A CZ  1 
ATOM   4820  N  NH1 . ARG A 1 625 ? 225.415 171.370 172.062 1.00 63.15  ? 625 ARG A NH1 1 
ATOM   4821  N  NH2 . ARG A 1 625 ? 225.061 171.990 174.237 1.00 63.15  ? 625 ARG A NH2 1 
ATOM   4822  N  N   . GLN A 1 626 ? 226.974 176.099 169.745 1.00 62.83  ? 626 GLN A N   1 
ATOM   4823  C  CA  . GLN A 1 626 ? 226.065 175.658 168.696 1.00 62.83  ? 626 GLN A CA  1 
ATOM   4824  C  C   . GLN A 1 626 ? 226.565 176.070 167.321 1.00 62.83  ? 626 GLN A C   1 
ATOM   4825  O  O   . GLN A 1 626 ? 226.417 175.314 166.354 1.00 62.83  ? 626 GLN A O   1 
ATOM   4826  C  CB  . GLN A 1 626 ? 224.661 176.204 168.947 1.00 62.83  ? 626 GLN A CB  1 
ATOM   4827  C  CG  . GLN A 1 626 ? 223.575 175.499 168.148 1.00 62.83  ? 626 GLN A CG  1 
ATOM   4828  C  CD  . GLN A 1 626 ? 223.494 174.015 168.443 1.00 62.83  ? 626 GLN A CD  1 
ATOM   4829  O  OE1 . GLN A 1 626 ? 223.356 173.198 167.535 1.00 62.83  ? 626 GLN A OE1 1 
ATOM   4830  N  NE2 . GLN A 1 626 ? 223.579 173.658 169.719 1.00 62.83  ? 626 GLN A NE2 1 
ATOM   4831  N  N   . LEU A 1 627 ? 227.144 177.266 167.201 1.00 57.76  ? 627 LEU A N   1 
ATOM   4832  C  CA  . LEU A 1 627 ? 227.750 177.623 165.924 1.00 57.76  ? 627 LEU A CA  1 
ATOM   4833  C  C   . LEU A 1 627 ? 228.886 176.675 165.586 1.00 57.76  ? 627 LEU A C   1 
ATOM   4834  O  O   . LEU A 1 627 ? 229.035 176.257 164.430 1.00 57.76  ? 627 LEU A O   1 
ATOM   4835  C  CB  . LEU A 1 627 ? 228.254 179.062 165.930 1.00 57.76  ? 627 LEU A CB  1 
ATOM   4836  C  CG  . LEU A 1 627 ? 227.277 180.143 165.478 1.00 57.76  ? 627 LEU A CG  1 
ATOM   4837  C  CD1 . LEU A 1 627 ? 226.293 180.434 166.568 1.00 57.76  ? 627 LEU A CD1 1 
ATOM   4838  C  CD2 . LEU A 1 627 ? 228.022 181.404 165.070 1.00 57.76  ? 627 LEU A CD2 1 
ATOM   4839  N  N   . ALA A 1 628 ? 229.696 176.319 166.584 1.00 61.91  ? 628 ALA A N   1 
ATOM   4840  C  CA  . ALA A 1 628 ? 230.778 175.374 166.339 1.00 61.91  ? 628 ALA A CA  1 
ATOM   4841  C  C   . ALA A 1 628 ? 230.232 174.056 165.812 1.00 61.91  ? 628 ALA A C   1 
ATOM   4842  O  O   . ALA A 1 628 ? 230.774 173.476 164.866 1.00 61.91  ? 628 ALA A O   1 
ATOM   4843  C  CB  . ALA A 1 628 ? 231.582 175.155 167.619 1.00 61.91  ? 628 ALA A CB  1 
ATOM   4844  N  N   . GLU A 1 629 ? 229.141 173.576 166.411 1.00 67.51  ? 629 GLU A N   1 
ATOM   4845  C  CA  . GLU A 1 629 ? 228.560 172.303 165.990 1.00 67.51  ? 629 GLU A CA  1 
ATOM   4846  C  C   . GLU A 1 629 ? 227.961 172.394 164.590 1.00 67.51  ? 629 GLU A C   1 
ATOM   4847  O  O   . GLU A 1 629 ? 228.070 171.452 163.798 1.00 67.51  ? 629 GLU A O   1 
ATOM   4848  C  CB  . GLU A 1 629 ? 227.503 171.851 166.997 1.00 67.51  ? 629 GLU A CB  1 
ATOM   4849  C  CG  . GLU A 1 629 ? 227.129 170.382 166.886 1.00 67.51  ? 629 GLU A CG  1 
ATOM   4850  C  CD  . GLU A 1 629 ? 226.627 169.807 168.195 1.00 67.51  ? 629 GLU A CD  1 
ATOM   4851  O  OE1 . GLU A 1 629 ? 226.790 170.472 169.240 1.00 67.51  ? 629 GLU A OE1 1 
ATOM   4852  O  OE2 . GLU A 1 629 ? 226.069 168.689 168.181 1.00 67.51  ? 629 GLU A OE2 1 
ATOM   4853  N  N   . TRP A 1 630 ? 227.314 173.515 164.270 1.00 62.12  ? 630 TRP A N   1 
ATOM   4854  C  CA  . TRP A 1 630 ? 226.681 173.655 162.963 1.00 62.12  ? 630 TRP A CA  1 
ATOM   4855  C  C   . TRP A 1 630 ? 227.723 173.764 161.864 1.00 62.12  ? 630 TRP A C   1 
ATOM   4856  O  O   . TRP A 1 630 ? 227.499 173.309 160.736 1.00 62.12  ? 630 TRP A O   1 
ATOM   4857  C  CB  . TRP A 1 630 ? 225.773 174.881 162.946 1.00 62.12  ? 630 TRP A CB  1 
ATOM   4858  C  CG  . TRP A 1 630 ? 224.535 174.744 163.767 1.00 62.12  ? 630 TRP A CG  1 
ATOM   4859  C  CD1 . TRP A 1 630 ? 224.310 173.852 164.765 1.00 62.12  ? 630 TRP A CD1 1 
ATOM   4860  C  CD2 . TRP A 1 630 ? 223.363 175.555 163.683 1.00 62.12  ? 630 TRP A CD2 1 
ATOM   4861  N  NE1 . TRP A 1 630 ? 223.065 174.043 165.300 1.00 62.12  ? 630 TRP A NE1 1 
ATOM   4862  C  CE2 . TRP A 1 630 ? 222.462 175.086 164.651 1.00 62.12  ? 630 TRP A CE2 1 
ATOM   4863  C  CE3 . TRP A 1 630 ? 222.985 176.627 162.874 1.00 62.12  ? 630 TRP A CE3 1 
ATOM   4864  C  CZ2 . TRP A 1 630 ? 221.209 175.649 164.834 1.00 62.12  ? 630 TRP A CZ2 1 
ATOM   4865  C  CZ3 . TRP A 1 630 ? 221.743 177.186 163.057 1.00 62.12  ? 630 TRP A CZ3 1 
ATOM   4866  C  CH2 . TRP A 1 630 ? 220.868 176.697 164.030 1.00 62.12  ? 630 TRP A CH2 1 
ATOM   4867  N  N   . ARG A 1 631 ? 228.870 174.372 162.173 1.00 69.76  ? 631 ARG A N   1 
ATOM   4868  C  CA  . ARG A 1 631 ? 229.934 174.514 161.185 1.00 69.76  ? 631 ARG A CA  1 
ATOM   4869  C  C   . ARG A 1 631 ? 230.434 173.170 160.672 1.00 69.76  ? 631 ARG A C   1 
ATOM   4870  O  O   . ARG A 1 631 ? 230.998 173.109 159.574 1.00 69.76  ? 631 ARG A O   1 
ATOM   4871  C  CB  . ARG A 1 631 ? 231.092 175.312 161.793 1.00 69.76  ? 631 ARG A CB  1 
ATOM   4872  C  CG  . ARG A 1 631 ? 232.200 175.686 160.820 1.00 69.76  ? 631 ARG A CG  1 
ATOM   4873  C  CD  . ARG A 1 631 ? 233.126 176.742 161.411 1.00 69.76  ? 631 ARG A CD  1 
ATOM   4874  N  NE  . ARG A 1 631 ? 233.637 176.361 162.722 1.00 69.76  ? 631 ARG A NE  1 
ATOM   4875  C  CZ  . ARG A 1 631 ? 234.391 177.139 163.486 1.00 69.76  ? 631 ARG A CZ  1 
ATOM   4876  N  NH1 . ARG A 1 631 ? 234.759 178.347 163.093 1.00 69.76  ? 631 ARG A NH1 1 
ATOM   4877  N  NH2 . ARG A 1 631 ? 234.787 176.694 164.675 1.00 69.76  ? 631 ARG A NH2 1 
ATOM   4878  N  N   . SER A 1 632 ? 230.219 172.091 161.429 1.00 70.62  ? 632 SER A N   1 
ATOM   4879  C  CA  . SER A 1 632 ? 230.757 170.788 161.051 1.00 70.62  ? 632 SER A CA  1 
ATOM   4880  C  C   . SER A 1 632 ? 230.235 170.326 159.700 1.00 70.62  ? 632 SER A C   1 
ATOM   4881  O  O   . SER A 1 632 ? 230.871 169.497 159.041 1.00 70.62  ? 632 SER A O   1 
ATOM   4882  C  CB  . SER A 1 632 ? 230.418 169.754 162.119 1.00 70.62  ? 632 SER A CB  1 
ATOM   4883  O  OG  . SER A 1 632 ? 229.022 169.528 162.165 1.00 70.62  ? 632 SER A OG  1 
ATOM   4884  N  N   . GLN A 1 633 ? 229.094 170.842 159.269 1.00 76.04  ? 633 GLN A N   1 
ATOM   4885  C  CA  . GLN A 1 633 ? 228.498 170.477 157.994 1.00 76.04  ? 633 GLN A CA  1 
ATOM   4886  C  C   . GLN A 1 633 ? 228.441 171.708 157.093 1.00 76.04  ? 633 GLN A C   1 
ATOM   4887  O  O   . GLN A 1 633 ? 228.998 172.763 157.408 1.00 76.04  ? 633 GLN A O   1 
ATOM   4888  C  CB  . GLN A 1 633 ? 227.115 169.862 158.207 1.00 76.04  ? 633 GLN A CB  1 
ATOM   4889  C  CG  . GLN A 1 633 ? 227.145 168.537 158.944 1.00 76.04  ? 633 GLN A CG  1 
ATOM   4890  C  CD  . GLN A 1 633 ? 227.930 167.477 158.199 1.00 76.04  ? 633 GLN A CD  1 
ATOM   4891  O  OE1 . GLN A 1 633 ? 229.026 167.095 158.610 1.00 76.04  ? 633 GLN A OE1 1 
ATOM   4892  N  NE2 . GLN A 1 633 ? 227.372 166.994 157.095 1.00 76.04  ? 633 GLN A NE2 1 
ATOM   4893  N  N   . ASN A 1 634 ? 227.755 171.565 155.959 1.00 83.10  ? 634 ASN A N   1 
ATOM   4894  C  CA  . ASN A 1 634 ? 227.680 172.635 154.973 1.00 83.10  ? 634 ASN A CA  1 
ATOM   4895  C  C   . ASN A 1 634 ? 226.925 173.860 155.474 1.00 83.10  ? 634 ASN A C   1 
ATOM   4896  O  O   . ASN A 1 634 ? 226.780 174.825 154.717 1.00 83.10  ? 634 ASN A O   1 
ATOM   4897  C  CB  . ASN A 1 634 ? 227.025 172.113 153.694 1.00 83.10  ? 634 ASN A CB  1 
ATOM   4898  C  CG  . ASN A 1 634 ? 227.706 170.869 153.157 1.00 83.10  ? 634 ASN A CG  1 
ATOM   4899  O  OD1 . ASN A 1 634 ? 228.927 170.733 153.234 1.00 83.10  ? 634 ASN A OD1 1 
ATOM   4900  N  ND2 . ASN A 1 634 ? 226.916 169.951 152.611 1.00 83.10  ? 634 ASN A ND2 1 
ATOM   4901  N  N   . ILE A 1 635 ? 226.437 173.846 156.715 1.00 78.48  ? 635 ILE A N   1 
ATOM   4902  C  CA  . ILE A 1 635 ? 225.781 175.023 157.267 1.00 78.48  ? 635 ILE A CA  1 
ATOM   4903  C  C   . ILE A 1 635 ? 226.791 176.156 157.367 1.00 78.48  ? 635 ILE A C   1 
ATOM   4904  O  O   . ILE A 1 635 ? 227.898 175.979 157.891 1.00 78.48  ? 635 ILE A O   1 
ATOM   4905  C  CB  . ILE A 1 635 ? 225.162 174.688 158.630 1.00 78.48  ? 635 ILE A CB  1 
ATOM   4906  C  CG1 . ILE A 1 635 ? 224.314 173.420 158.526 1.00 78.48  ? 635 ILE A CG1 1 
ATOM   4907  C  CG2 . ILE A 1 635 ? 224.303 175.838 159.122 1.00 78.48  ? 635 ILE A CG2 1 
ATOM   4908  C  CD1 . ILE A 1 635 ? 223.161 173.535 157.550 1.00 78.48  ? 635 ILE A CD1 1 
ATOM   4909  N  N   . HIS A 1 636 ? 226.414 177.334 156.864 1.00 74.47  ? 636 HIS A N   1 
ATOM   4910  C  CA  . HIS A 1 636 ? 227.338 178.455 156.737 1.00 74.47  ? 636 HIS A CA  1 
ATOM   4911  C  C   . HIS A 1 636 ? 227.100 179.589 157.724 1.00 74.47  ? 636 HIS A C   1 
ATOM   4912  O  O   . HIS A 1 636 ? 228.043 180.319 158.029 1.00 74.47  ? 636 HIS A O   1 
ATOM   4913  C  CB  . HIS A 1 636 ? 227.287 179.021 155.313 1.00 74.47  ? 636 HIS A CB  1 
ATOM   4914  C  CG  . HIS A 1 636 ? 225.928 179.487 154.896 1.00 74.47  ? 636 HIS A CG  1 
ATOM   4915  N  ND1 . HIS A 1 636 ? 224.926 178.618 154.522 1.00 74.47  ? 636 HIS A ND1 1 
ATOM   4916  C  CD2 . HIS A 1 636 ? 225.406 180.732 154.790 1.00 74.47  ? 636 HIS A CD2 1 
ATOM   4917  C  CE1 . HIS A 1 636 ? 223.844 179.307 154.205 1.00 74.47  ? 636 HIS A CE1 1 
ATOM   4918  N  NE2 . HIS A 1 636 ? 224.108 180.592 154.360 1.00 74.47  ? 636 HIS A NE2 1 
ATOM   4919  N  N   . ILE A 1 637 ? 225.879 179.752 158.230 1.00 66.72  ? 637 ILE A N   1 
ATOM   4920  C  CA  . ILE A 1 637 ? 225.559 180.748 159.255 1.00 66.72  ? 637 ILE A CA  1 
ATOM   4921  C  C   . ILE A 1 637 ? 225.881 182.149 158.739 1.00 66.72  ? 637 ILE A C   1 
ATOM   4922  O  O   . ILE A 1 637 ? 226.928 182.712 159.090 1.00 66.72  ? 637 ILE A O   1 
ATOM   4923  C  CB  . ILE A 1 637 ? 226.291 180.455 160.576 1.00 66.72  ? 637 ILE A CB  1 
ATOM   4924  C  CG1 . ILE A 1 637 ? 225.897 179.083 161.127 1.00 66.72  ? 637 ILE A CG1 1 
ATOM   4925  C  CG2 . ILE A 1 637 ? 225.937 181.490 161.637 1.00 66.72  ? 637 ILE A CG2 1 
ATOM   4926  C  CD1 . ILE A 1 637 ? 226.788 177.943 160.675 1.00 66.72  ? 637 ILE A CD1 1 
ATOM   4927  N  N   . PRO A 1 638 ? 225.054 182.720 157.856 1.00 62.64  ? 638 PRO A N   1 
ATOM   4928  C  CA  . PRO A 1 638 ? 225.335 184.082 157.366 1.00 62.64  ? 638 PRO A CA  1 
ATOM   4929  C  C   . PRO A 1 638 ? 225.432 185.114 158.474 1.00 62.64  ? 638 PRO A C   1 
ATOM   4930  O  O   . PRO A 1 638 ? 226.303 185.989 158.425 1.00 62.64  ? 638 PRO A O   1 
ATOM   4931  C  CB  . PRO A 1 638 ? 224.152 184.362 156.431 1.00 62.64  ? 638 PRO A CB  1 
ATOM   4932  C  CG  . PRO A 1 638 ? 223.073 183.486 156.921 1.00 62.64  ? 638 PRO A CG  1 
ATOM   4933  C  CD  . PRO A 1 638 ? 223.738 182.237 157.413 1.00 62.64  ? 638 PRO A CD  1 
ATOM   4934  N  N   . ALA A 1 639 ? 224.561 185.035 159.476 1.00 59.73  ? 639 ALA A N   1 
ATOM   4935  C  CA  . ALA A 1 639 ? 224.727 185.807 160.698 1.00 59.73  ? 639 ALA A CA  1 
ATOM   4936  C  C   . ALA A 1 639 ? 224.035 185.064 161.829 1.00 59.73  ? 639 ALA A C   1 
ATOM   4937  O  O   . ALA A 1 639 ? 223.141 184.250 161.598 1.00 59.73  ? 639 ALA A O   1 
ATOM   4938  C  CB  . ALA A 1 639 ? 224.163 187.225 160.557 1.00 59.73  ? 639 ALA A CB  1 
ATOM   4939  N  N   . LEU A 1 640 ? 224.452 185.343 163.062 1.00 51.80  ? 640 LEU A N   1 
ATOM   4940  C  CA  . LEU A 1 640 ? 223.709 184.853 164.212 1.00 51.80  ? 640 LEU A CA  1 
ATOM   4941  C  C   . LEU A 1 640 ? 223.595 185.950 165.248 1.00 51.80  ? 640 LEU A C   1 
ATOM   4942  O  O   . LEU A 1 640 ? 224.542 186.705 165.478 1.00 51.80  ? 640 LEU A O   1 
ATOM   4943  C  CB  . LEU A 1 640 ? 224.333 183.603 164.834 1.00 51.80  ? 640 LEU A CB  1 
ATOM   4944  C  CG  . LEU A 1 640 ? 223.454 183.065 165.963 1.00 51.80  ? 640 LEU A CG  1 
ATOM   4945  C  CD1 . LEU A 1 640 ? 223.197 181.580 165.820 1.00 51.80  ? 640 LEU A CD1 1 
ATOM   4946  C  CD2 . LEU A 1 640 ? 224.085 183.360 167.307 1.00 51.80  ? 640 LEU A CD2 1 
ATOM   4947  N  N   . SER A 1 641 ? 222.425 186.029 165.872 1.00 48.92  ? 641 SER A N   1 
ATOM   4948  C  CA  . SER A 1 641 ? 222.095 187.125 166.775 1.00 48.92  ? 641 SER A CA  1 
ATOM   4949  C  C   . SER A 1 641 ? 221.550 186.578 168.087 1.00 48.92  ? 641 SER A C   1 
ATOM   4950  O  O   . SER A 1 641 ? 220.386 186.177 168.162 1.00 48.92  ? 641 SER A O   1 
ATOM   4951  C  CB  . SER A 1 641 ? 221.091 188.064 166.132 1.00 48.92  ? 641 SER A CB  1 
ATOM   4952  O  OG  . SER A 1 641 ? 220.442 188.832 167.124 1.00 48.92  ? 641 SER A OG  1 
ATOM   4953  N  N   . VAL A 1 642 ? 222.389 186.558 169.114 1.00 47.62  ? 642 VAL A N   1 
ATOM   4954  C  CA  . VAL A 1 642 ? 221.911 186.509 170.486 1.00 47.62  ? 642 VAL A CA  1 
ATOM   4955  C  C   . VAL A 1 642 ? 221.323 187.875 170.780 1.00 47.62  ? 642 VAL A C   1 
ATOM   4956  O  O   . VAL A 1 642 ? 221.648 188.850 170.099 1.00 47.62  ? 642 VAL A O   1 
ATOM   4957  C  CB  . VAL A 1 642 ? 223.041 186.161 171.464 1.00 47.62  ? 642 VAL A CB  1 
ATOM   4958  C  CG1 . VAL A 1 642 ? 223.620 184.812 171.123 1.00 47.62  ? 642 VAL A CG1 1 
ATOM   4959  C  CG2 . VAL A 1 642 ? 224.118 187.217 171.428 1.00 47.62  ? 642 VAL A CG2 1 
ATOM   4960  N  N   . ASN A 1 643 ? 220.431 187.955 171.760 1.00 54.00  ? 643 ASN A N   1 
ATOM   4961  C  CA  . ASN A 1 643 ? 219.755 189.225 171.990 1.00 54.00  ? 643 ASN A CA  1 
ATOM   4962  C  C   . ASN A 1 643 ? 220.577 190.135 172.894 1.00 54.00  ? 643 ASN A C   1 
ATOM   4963  O  O   . ASN A 1 643 ? 221.011 191.216 172.481 1.00 54.00  ? 643 ASN A O   1 
ATOM   4964  C  CB  . ASN A 1 643 ? 218.372 188.991 172.579 1.00 54.00  ? 643 ASN A CB  1 
ATOM   4965  C  CG  . ASN A 1 643 ? 217.586 190.267 172.706 1.00 54.00  ? 643 ASN A CG  1 
ATOM   4966  O  OD1 . ASN A 1 643 ? 217.792 191.043 173.633 1.00 54.00  ? 643 ASN A OD1 1 
ATOM   4967  N  ND2 . ASN A 1 643 ? 216.685 190.499 171.767 1.00 54.00  ? 643 ASN A ND2 1 
ATOM   4968  N  N   . LEU A 1 644 ? 220.789 189.715 174.140 1.00 58.76  ? 644 LEU A N   1 
ATOM   4969  C  CA  . LEU A 1 644 ? 221.548 190.436 175.160 1.00 58.76  ? 644 LEU A CA  1 
ATOM   4970  C  C   . LEU A 1 644 ? 220.950 191.790 175.515 1.00 58.76  ? 644 LEU A C   1 
ATOM   4971  O  O   . LEU A 1 644 ? 221.636 192.613 176.128 1.00 58.76  ? 644 LEU A O   1 
ATOM   4972  C  CB  . LEU A 1 644 ? 223.013 190.629 174.752 1.00 58.76  ? 644 LEU A CB  1 
ATOM   4973  C  CG  . LEU A 1 644 ? 223.771 189.366 174.341 1.00 58.76  ? 644 LEU A CG  1 
ATOM   4974  C  CD1 . LEU A 1 644 ? 225.230 189.680 174.059 1.00 58.76  ? 644 LEU A CD1 1 
ATOM   4975  C  CD2 . LEU A 1 644 ? 223.646 188.269 175.385 1.00 58.76  ? 644 LEU A CD2 1 
ATOM   4976  N  N   . SER A 1 645 ? 219.701 192.051 175.153 1.00 61.64  ? 645 SER A N   1 
ATOM   4977  C  CA  . SER A 1 645 ? 219.045 193.305 175.507 1.00 61.64  ? 645 SER A CA  1 
ATOM   4978  C  C   . SER A 1 645 ? 217.767 193.111 176.301 1.00 61.64  ? 645 SER A C   1 
ATOM   4979  O  O   . SER A 1 645 ? 217.518 193.855 177.250 1.00 61.64  ? 645 SER A O   1 
ATOM   4980  C  CB  . SER A 1 645 ? 218.730 194.120 174.248 1.00 61.64  ? 645 SER A CB  1 
ATOM   4981  O  OG  . SER A 1 645 ? 218.393 195.454 174.585 1.00 61.64  ? 645 SER A OG  1 
ATOM   4982  N  N   . ALA A 1 646 ? 216.943 192.135 175.934 1.00 63.90  ? 646 ALA A N   1 
ATOM   4983  C  CA  . ALA A 1 646 ? 215.786 191.790 176.745 1.00 63.90  ? 646 ALA A CA  1 
ATOM   4984  C  C   . ALA A 1 646 ? 216.167 191.018 177.996 1.00 63.90  ? 646 ALA A C   1 
ATOM   4985  O  O   . ALA A 1 646 ? 215.315 190.822 178.869 1.00 63.90  ? 646 ALA A O   1 
ATOM   4986  C  CB  . ALA A 1 646 ? 214.785 190.975 175.923 1.00 63.90  ? 646 ALA A CB  1 
ATOM   4987  N  N   . LEU A 1 647 ? 217.419 190.583 178.102 1.00 66.96  ? 647 LEU A N   1 
ATOM   4988  C  CA  . LEU A 1 647 ? 217.913 189.861 179.264 1.00 66.96  ? 647 LEU A CA  1 
ATOM   4989  C  C   . LEU A 1 647 ? 218.394 190.791 180.368 1.00 66.96  ? 647 LEU A C   1 
ATOM   4990  O  O   . LEU A 1 647 ? 218.850 190.309 181.408 1.00 66.96  ? 647 LEU A O   1 
ATOM   4991  C  CB  . LEU A 1 647 ? 219.042 188.915 178.848 1.00 66.96  ? 647 LEU A CB  1 
ATOM   4992  C  CG  . LEU A 1 647 ? 218.762 188.052 177.615 1.00 66.96  ? 647 LEU A CG  1 
ATOM   4993  C  CD1 . LEU A 1 647 ? 220.038 187.412 177.120 1.00 66.96  ? 647 LEU A CD1 1 
ATOM   4994  C  CD2 . LEU A 1 647 ? 217.726 186.992 177.920 1.00 66.96  ? 647 LEU A CD2 1 
ATOM   4995  N  N   . HIS A 1 648 ? 218.308 192.104 180.160 1.00 74.48  ? 648 HIS A N   1 
ATOM   4996  C  CA  . HIS A 1 648 ? 218.582 193.106 181.188 1.00 74.48  ? 648 HIS A CA  1 
ATOM   4997  C  C   . HIS A 1 648 ? 220.009 192.982 181.721 1.00 74.48  ? 648 HIS A C   1 
ATOM   4998  O  O   . HIS A 1 648 ? 220.243 192.765 182.911 1.00 74.48  ? 648 HIS A O   1 
ATOM   4999  C  CB  . HIS A 1 648 ? 217.564 193.011 182.330 1.00 74.48  ? 648 HIS A CB  1 
ATOM   5000  C  CG  . HIS A 1 648 ? 216.139 193.119 181.886 1.00 74.48  ? 648 HIS A CG  1 
ATOM   5001  N  ND1 . HIS A 1 648 ? 215.080 192.802 182.708 1.00 74.48  ? 648 HIS A ND1 1 
ATOM   5002  C  CD2 . HIS A 1 648 ? 215.598 193.509 180.708 1.00 74.48  ? 648 HIS A CD2 1 
ATOM   5003  C  CE1 . HIS A 1 648 ? 213.947 192.992 182.056 1.00 74.48  ? 648 HIS A CE1 1 
ATOM   5004  N  NE2 . HIS A 1 648 ? 214.234 193.420 180.840 1.00 74.48  ? 648 HIS A NE2 1 
ATOM   5005  N  N   . PHE A 1 649 ? 220.969 193.123 180.814 1.00 71.97  ? 649 PHE A N   1 
ATOM   5006  C  CA  . PHE A 1 649 ? 222.370 193.094 181.202 1.00 71.97  ? 649 PHE A CA  1 
ATOM   5007  C  C   . PHE A 1 649 ? 222.743 194.348 181.979 1.00 71.97  ? 649 PHE A C   1 
ATOM   5008  O  O   . PHE A 1 649 ? 222.191 195.427 181.754 1.00 71.97  ? 649 PHE A O   1 
ATOM   5009  C  CB  . PHE A 1 649 ? 223.269 192.962 179.978 1.00 71.97  ? 649 PHE A CB  1 
ATOM   5010  C  CG  . PHE A 1 649 ? 223.634 191.552 179.650 1.00 71.97  ? 649 PHE A CG  1 
ATOM   5011  C  CD1 . PHE A 1 649 ? 224.813 191.004 180.117 1.00 71.97  ? 649 PHE A CD1 1 
ATOM   5012  C  CD2 . PHE A 1 649 ? 222.802 190.773 178.873 1.00 71.97  ? 649 PHE A CD2 1 
ATOM   5013  C  CE1 . PHE A 1 649 ? 225.157 189.707 179.814 1.00 71.97  ? 649 PHE A CE1 1 
ATOM   5014  C  CE2 . PHE A 1 649 ? 223.139 189.474 178.569 1.00 71.97  ? 649 PHE A CE2 1 
ATOM   5015  C  CZ  . PHE A 1 649 ? 224.320 188.942 179.037 1.00 71.97  ? 649 PHE A CZ  1 
ATOM   5016  N  N   . ARG A 1 650 ? 223.681 194.194 182.901 1.00 82.81  ? 650 ARG A N   1 
ATOM   5017  C  CA  . ARG A 1 650 ? 224.234 195.323 183.626 1.00 82.81  ? 650 ARG A CA  1 
ATOM   5018  C  C   . ARG A 1 650 ? 225.622 195.655 183.089 1.00 82.81  ? 650 ARG A C   1 
ATOM   5019  O  O   . ARG A 1 650 ? 226.242 194.873 182.367 1.00 82.81  ? 650 ARG A O   1 
ATOM   5020  C  CB  . ARG A 1 650 ? 224.290 195.026 185.123 1.00 82.81  ? 650 ARG A CB  1 
ATOM   5021  C  CG  . ARG A 1 650 ? 222.928 194.983 185.798 1.00 82.81  ? 650 ARG A CG  1 
ATOM   5022  C  CD  . ARG A 1 650 ? 222.347 196.379 185.953 1.00 82.81  ? 650 ARG A CD  1 
ATOM   5023  N  NE  . ARG A 1 650 ? 221.430 196.713 184.870 1.00 82.81  ? 650 ARG A NE  1 
ATOM   5024  C  CZ  . ARG A 1 650 ? 220.164 196.323 184.812 1.00 82.81  ? 650 ARG A CZ  1 
ATOM   5025  N  NH1 . ARG A 1 650 ? 219.623 195.584 185.767 1.00 82.81  ? 650 ARG A NH1 1 
ATOM   5026  N  NH2 . ARG A 1 650 ? 219.421 196.687 183.771 1.00 82.81  ? 650 ARG A NH2 1 
ATOM   5027  N  N   . SER A 1 651 ? 226.111 196.839 183.450 1.00 84.90  ? 651 SER A N   1 
ATOM   5028  C  CA  . SER A 1 651 ? 227.432 197.257 183.004 1.00 84.90  ? 651 SER A CA  1 
ATOM   5029  C  C   . SER A 1 651 ? 228.551 196.635 183.826 1.00 84.90  ? 651 SER A C   1 
ATOM   5030  O  O   . SER A 1 651 ? 229.719 196.740 183.437 1.00 84.90  ? 651 SER A O   1 
ATOM   5031  C  CB  . SER A 1 651 ? 227.547 198.782 183.054 1.00 84.90  ? 651 SER A CB  1 
ATOM   5032  O  OG  . SER A 1 651 ? 227.439 199.257 184.385 1.00 84.90  ? 651 SER A OG  1 
ATOM   5033  N  N   . ASN A 1 652 ? 228.222 195.991 184.947 1.00 86.05  ? 652 ASN A N   1 
ATOM   5034  C  CA  . ASN A 1 652 ? 229.258 195.467 185.830 1.00 86.05  ? 652 ASN A CA  1 
ATOM   5035  C  C   . ASN A 1 652 ? 230.068 194.372 185.151 1.00 86.05  ? 652 ASN A C   1 
ATOM   5036  O  O   . ASN A 1 652 ? 231.302 194.366 185.226 1.00 86.05  ? 652 ASN A O   1 
ATOM   5037  C  CB  . ASN A 1 652 ? 228.630 194.946 187.122 1.00 86.05  ? 652 ASN A CB  1 
ATOM   5038  C  CG  . ASN A 1 652 ? 229.660 194.664 188.198 1.00 86.05  ? 652 ASN A CG  1 
ATOM   5039  O  OD1 . ASN A 1 652 ? 230.598 195.437 188.393 1.00 86.05  ? 652 ASN A OD1 1 
ATOM   5040  N  ND2 . ASN A 1 652 ? 229.489 193.552 188.904 1.00 86.05  ? 652 ASN A ND2 1 
ATOM   5041  N  N   . GLN A 1 653 ? 229.396 193.438 184.479 1.00 83.03  ? 653 GLN A N   1 
ATOM   5042  C  CA  . GLN A 1 653 ? 230.074 192.303 183.863 1.00 83.03  ? 653 GLN A CA  1 
ATOM   5043  C  C   . GLN A 1 653 ? 229.675 192.130 182.405 1.00 83.03  ? 653 GLN A C   1 
ATOM   5044  O  O   . GLN A 1 653 ? 229.673 191.005 181.898 1.00 83.03  ? 653 GLN A O   1 
ATOM   5045  C  CB  . GLN A 1 653 ? 229.789 191.015 184.641 1.00 83.03  ? 653 GLN A CB  1 
ATOM   5046  C  CG  . GLN A 1 653 ? 230.065 191.108 186.133 1.00 83.03  ? 653 GLN A CG  1 
ATOM   5047  C  CD  . GLN A 1 653 ? 229.805 189.801 186.858 1.00 83.03  ? 653 GLN A CD  1 
ATOM   5048  O  OE1 . GLN A 1 653 ? 229.423 188.804 186.245 1.00 83.03  ? 653 GLN A OE1 1 
ATOM   5049  N  NE2 . GLN A 1 653 ? 230.008 189.802 188.170 1.00 83.03  ? 653 GLN A NE2 1 
ATOM   5050  N  N   . LEU A 1 654 ? 229.313 193.213 181.728 1.00 84.95  ? 654 LEU A N   1 
ATOM   5051  C  CA  . LEU A 1 654 ? 228.914 193.103 180.327 1.00 84.95  ? 654 LEU A CA  1 
ATOM   5052  C  C   . LEU A 1 654 ? 230.039 192.617 179.420 1.00 84.95  ? 654 LEU A C   1 
ATOM   5053  O  O   . LEU A 1 654 ? 229.814 191.661 178.657 1.00 84.95  ? 654 LEU A O   1 
ATOM   5054  C  CB  . LEU A 1 654 ? 228.350 194.446 179.850 1.00 84.95  ? 654 LEU A CB  1 
ATOM   5055  C  CG  . LEU A 1 654 ? 227.579 194.454 178.526 1.00 84.95  ? 654 LEU A CG  1 
ATOM   5056  C  CD1 . LEU A 1 654 ? 226.435 195.453 178.586 1.00 84.95  ? 654 LEU A CD1 1 
ATOM   5057  C  CD2 . LEU A 1 654 ? 228.496 194.771 177.354 1.00 84.95  ? 654 LEU A CD2 1 
ATOM   5058  N  N   . PRO A 1 655 ? 231.254 193.200 179.436 1.00 85.01  ? 655 PRO A N   1 
ATOM   5059  C  CA  . PRO A 1 655 ? 232.225 192.859 178.387 1.00 85.01  ? 655 PRO A CA  1 
ATOM   5060  C  C   . PRO A 1 655 ? 232.971 191.553 178.611 1.00 85.01  ? 655 PRO A C   1 
ATOM   5061  O  O   . PRO A 1 655 ? 233.298 190.860 177.646 1.00 85.01  ? 655 PRO A O   1 
ATOM   5062  C  CB  . PRO A 1 655 ? 233.186 194.051 178.414 1.00 85.01  ? 655 PRO A CB  1 
ATOM   5063  C  CG  . PRO A 1 655 ? 233.183 194.478 179.831 1.00 85.01  ? 655 PRO A CG  1 
ATOM   5064  C  CD  . PRO A 1 655 ? 231.799 194.210 180.365 1.00 85.01  ? 655 PRO A CD  1 
ATOM   5065  N  N   . ASN A 1 656 ? 233.266 191.217 179.868 1.00 82.68  ? 656 ASN A N   1 
ATOM   5066  C  CA  . ASN A 1 656 ? 234.171 190.103 180.132 1.00 82.68  ? 656 ASN A CA  1 
ATOM   5067  C  C   . ASN A 1 656 ? 233.583 188.786 179.649 1.00 82.68  ? 656 ASN A C   1 
ATOM   5068  O  O   . ASN A 1 656 ? 234.269 187.987 179.002 1.00 82.68  ? 656 ASN A O   1 
ATOM   5069  C  CB  . ASN A 1 656 ? 234.504 190.040 181.622 1.00 82.68  ? 656 ASN A CB  1 
ATOM   5070  C  CG  . ASN A 1 656 ? 233.270 190.023 182.493 1.00 82.68  ? 656 ASN A CG  1 
ATOM   5071  O  OD1 . ASN A 1 656 ? 232.150 189.939 181.996 1.00 82.68  ? 656 ASN A OD1 1 
ATOM   5072  N  ND2 . ASN A 1 656 ? 233.468 190.105 183.804 1.00 82.68  ? 656 ASN A ND2 1 
ATOM   5073  N  N   . GLN A 1 657 ? 232.304 188.549 179.940 1.00 84.25  ? 657 GLN A N   1 
ATOM   5074  C  CA  . GLN A 1 657 ? 231.681 187.285 179.562 1.00 84.25  ? 657 GLN A CA  1 
ATOM   5075  C  C   . GLN A 1 657 ? 231.570 187.156 178.049 1.00 84.25  ? 657 GLN A C   1 
ATOM   5076  O  O   . GLN A 1 657 ? 231.907 186.110 177.479 1.00 84.25  ? 657 GLN A O   1 
ATOM   5077  C  CB  . GLN A 1 657 ? 230.306 187.163 180.218 1.00 84.25  ? 657 GLN A CB  1 
ATOM   5078  C  CG  . GLN A 1 657 ? 230.358 186.828 181.700 1.00 84.25  ? 657 GLN A CG  1 
ATOM   5079  C  CD  . GLN A 1 657 ? 229.137 187.315 182.453 1.00 84.25  ? 657 GLN A CD  1 
ATOM   5080  O  OE1 . GLN A 1 657 ? 228.139 187.713 181.851 1.00 84.25  ? 657 GLN A OE1 1 
ATOM   5081  N  NE2 . GLN A 1 657 ? 229.209 187.285 183.779 1.00 84.25  ? 657 GLN A NE2 1 
ATOM   5082  N  N   . VAL A 1 658 ? 231.100 188.210 177.379 1.00 83.48  ? 658 VAL A N   1 
ATOM   5083  C  CA  . VAL A 1 658 ? 230.965 188.158 175.932 1.00 83.48  ? 658 VAL A CA  1 
ATOM   5084  C  C   . VAL A 1 658 ? 232.322 188.032 175.262 1.00 83.48  ? 658 VAL A C   1 
ATOM   5085  O  O   . VAL A 1 658 ? 232.429 187.423 174.194 1.00 83.48  ? 658 VAL A O   1 
ATOM   5086  C  CB  . VAL A 1 658 ? 230.180 189.386 175.413 1.00 83.48  ? 658 VAL A CB  1 
ATOM   5087  C  CG1 . VAL A 1 658 ? 230.944 190.672 175.660 1.00 83.48  ? 658 VAL A CG1 1 
ATOM   5088  C  CG2 . VAL A 1 658 ? 229.861 189.235 173.933 1.00 83.48  ? 658 VAL A CG2 1 
ATOM   5089  N  N   . SER A 1 659 ? 233.374 188.579 175.872 1.00 85.95  ? 659 SER A N   1 
ATOM   5090  C  CA  . SER A 1 659 ? 234.709 188.439 175.306 1.00 85.95  ? 659 SER A CA  1 
ATOM   5091  C  C   . SER A 1 659 ? 235.236 187.020 175.476 1.00 85.95  ? 659 SER A C   1 
ATOM   5092  O  O   . SER A 1 659 ? 235.783 186.435 174.536 1.00 85.95  ? 659 SER A O   1 
ATOM   5093  C  CB  . SER A 1 659 ? 235.656 189.443 175.959 1.00 85.95  ? 659 SER A CB  1 
ATOM   5094  O  OG  . SER A 1 659 ? 235.568 189.363 177.370 1.00 85.95  ? 659 SER A OG  1 
ATOM   5095  N  N   . ASP A 1 660 ? 235.073 186.450 176.672 1.00 84.87  ? 660 ASP A N   1 
ATOM   5096  C  CA  . ASP A 1 660 ? 235.596 185.113 176.920 1.00 84.87  ? 660 ASP A CA  1 
ATOM   5097  C  C   . ASP A 1 660 ? 234.806 184.057 176.166 1.00 84.87  ? 660 ASP A C   1 
ATOM   5098  O  O   . ASP A 1 660 ? 235.328 182.969 175.897 1.00 84.87  ? 660 ASP A O   1 
ATOM   5099  C  CB  . ASP A 1 660 ? 235.591 184.814 178.417 1.00 84.87  ? 660 ASP A CB  1 
ATOM   5100  C  CG  . ASP A 1 660 ? 236.504 185.735 179.196 1.00 84.87  ? 660 ASP A CG  1 
ATOM   5101  O  OD1 . ASP A 1 660 ? 237.669 185.906 178.782 1.00 84.87  ? 660 ASP A OD1 1 
ATOM   5102  O  OD2 . ASP A 1 660 ? 236.063 186.280 180.229 1.00 84.87  ? 660 ASP A OD2 1 
ATOM   5103  N  N   . ALA A 1 661 ? 233.553 184.350 175.821 1.00 82.78  ? 661 ALA A N   1 
ATOM   5104  C  CA  . ALA A 1 661 ? 232.770 183.389 175.054 1.00 82.78  ? 661 ALA A CA  1 
ATOM   5105  C  C   . ALA A 1 661 ? 233.390 183.129 173.691 1.00 82.78  ? 661 ALA A C   1 
ATOM   5106  O  O   . ALA A 1 661 ? 233.241 182.033 173.142 1.00 82.78  ? 661 ALA A O   1 
ATOM   5107  C  CB  . ALA A 1 661 ? 231.332 183.884 174.901 1.00 82.78  ? 661 ALA A CB  1 
ATOM   5108  N  N   . MET A 1 662 ? 234.083 184.120 173.130 1.00 86.75  ? 662 MET A N   1 
ATOM   5109  C  CA  . MET A 1 662 ? 234.711 183.931 171.828 1.00 86.75  ? 662 MET A CA  1 
ATOM   5110  C  C   . MET A 1 662 ? 235.798 182.867 171.891 1.00 86.75  ? 662 MET A C   1 
ATOM   5111  O  O   . MET A 1 662 ? 235.791 181.911 171.105 1.00 86.75  ? 662 MET A O   1 
ATOM   5112  C  CB  . MET A 1 662 ? 235.287 185.255 171.329 1.00 86.75  ? 662 MET A CB  1 
ATOM   5113  C  CG  . MET A 1 662 ? 234.349 186.440 171.488 1.00 86.75  ? 662 MET A CG  1 
ATOM   5114  S  SD  . MET A 1 662 ? 233.045 186.462 170.250 1.00 86.75  ? 662 MET A SD  1 
ATOM   5115  C  CE  . MET A 1 662 ? 231.679 187.086 171.221 1.00 86.75  ? 662 MET A CE  1 
ATOM   5116  N  N   . HIS A 1 663 ? 236.728 183.002 172.833 1.00 89.80  ? 663 HIS A N   1 
ATOM   5117  C  CA  . HIS A 1 663 ? 237.829 182.061 172.966 1.00 89.80  ? 663 HIS A CA  1 
ATOM   5118  C  C   . HIS A 1 663 ? 237.436 180.785 173.695 1.00 89.80  ? 663 HIS A C   1 
ATOM   5119  O  O   . HIS A 1 663 ? 238.234 179.843 173.727 1.00 89.80  ? 663 HIS A O   1 
ATOM   5120  C  CB  . HIS A 1 663 ? 239.006 182.720 173.693 1.00 89.80  ? 663 HIS A CB  1 
ATOM   5121  C  CG  . HIS A 1 663 ? 238.987 182.525 175.176 1.00 89.80  ? 663 HIS A CG  1 
ATOM   5122  N  ND1 . HIS A 1 663 ? 238.354 183.400 176.032 1.00 89.80  ? 663 HIS A ND1 1 
ATOM   5123  C  CD2 . HIS A 1 663 ? 239.535 181.565 175.958 1.00 89.80  ? 663 HIS A CD2 1 
ATOM   5124  C  CE1 . HIS A 1 663 ? 238.505 182.983 177.276 1.00 89.80  ? 663 HIS A CE1 1 
ATOM   5125  N  NE2 . HIS A 1 663 ? 239.217 181.871 177.259 1.00 89.80  ? 663 HIS A NE2 1 
ATOM   5126  N  N   . ALA A 1 664 ? 236.238 180.733 174.284 1.00 87.27  ? 664 ALA A N   1 
ATOM   5127  C  CA  . ALA A 1 664 ? 235.797 179.505 174.933 1.00 87.27  ? 664 ALA A CA  1 
ATOM   5128  C  C   . ALA A 1 664 ? 235.713 178.348 173.950 1.00 87.27  ? 664 ALA A C   1 
ATOM   5129  O  O   . ALA A 1 664 ? 235.921 177.190 174.331 1.00 87.27  ? 664 ALA A O   1 
ATOM   5130  C  CB  . ALA A 1 664 ? 234.444 179.726 175.611 1.00 87.27  ? 664 ALA A CB  1 
ATOM   5131  N  N   . TRP A 1 665 ? 235.411 178.636 172.683 1.00 78.09  ? 665 TRP A N   1 
ATOM   5132  C  CA  . TRP A 1 665 ? 235.350 177.606 171.653 1.00 78.09  ? 665 TRP A CA  1 
ATOM   5133  C  C   . TRP A 1 665 ? 235.988 178.068 170.350 1.00 78.09  ? 665 TRP A C   1 
ATOM   5134  O  O   . TRP A 1 665 ? 235.892 177.365 169.340 1.00 78.09  ? 665 TRP A O   1 
ATOM   5135  C  CB  . TRP A 1 665 ? 233.905 177.169 171.403 1.00 78.09  ? 665 TRP A CB  1 
ATOM   5136  C  CG  . TRP A 1 665 ? 233.354 176.273 172.467 1.00 78.09  ? 665 TRP A CG  1 
ATOM   5137  C  CD1 . TRP A 1 665 ? 233.574 174.935 172.605 1.00 78.09  ? 665 TRP A CD1 1 
ATOM   5138  C  CD2 . TRP A 1 665 ? 232.481 176.649 173.539 1.00 78.09  ? 665 TRP A CD2 1 
ATOM   5139  N  NE1 . TRP A 1 665 ? 232.896 174.454 173.699 1.00 78.09  ? 665 TRP A NE1 1 
ATOM   5140  C  CE2 . TRP A 1 665 ? 232.217 175.487 174.289 1.00 78.09  ? 665 TRP A CE2 1 
ATOM   5141  C  CE3 . TRP A 1 665 ? 231.899 177.855 173.937 1.00 78.09  ? 665 TRP A CE3 1 
ATOM   5142  C  CZ2 . TRP A 1 665 ? 231.398 175.496 175.414 1.00 78.09  ? 665 TRP A CZ2 1 
ATOM   5143  C  CZ3 . TRP A 1 665 ? 231.086 177.862 175.055 1.00 78.09  ? 665 TRP A CZ3 1 
ATOM   5144  C  CH2 . TRP A 1 665 ? 230.843 176.690 175.780 1.00 78.09  ? 665 TRP A CH2 1 
ATOM   5145  N  N   . GLY A 1 666 ? 236.641 179.227 170.349 1.00 73.92  ? 666 GLY A N   1 
ATOM   5146  C  CA  . GLY A 1 666 ? 237.296 179.695 169.148 1.00 73.92  ? 666 GLY A CA  1 
ATOM   5147  C  C   . GLY A 1 666 ? 236.315 180.011 168.042 1.00 73.92  ? 666 GLY A C   1 
ATOM   5148  O  O   . GLY A 1 666 ? 236.272 179.313 167.025 1.00 73.92  ? 666 GLY A O   1 
ATOM   5149  N  N   . ILE A 1 667 ? 235.512 181.052 168.233 1.00 70.79  ? 667 ILE A N   1 
ATOM   5150  C  CA  . ILE A 1 667 ? 234.530 181.483 167.247 1.00 70.79  ? 667 ILE A CA  1 
ATOM   5151  C  C   . ILE A 1 667 ? 234.909 182.867 166.742 1.00 70.79  ? 667 ILE A C   1 
ATOM   5152  O  O   . ILE A 1 667 ? 235.323 183.736 167.519 1.00 70.79  ? 667 ILE A O   1 
ATOM   5153  C  CB  . ILE A 1 667 ? 233.100 181.473 167.823 1.00 70.79  ? 667 ILE A CB  1 
ATOM   5154  C  CG1 . ILE A 1 667 ? 232.093 181.908 166.756 1.00 70.79  ? 667 ILE A CG1 1 
ATOM   5155  C  CG2 . ILE A 1 667 ? 233.006 182.351 169.054 1.00 70.79  ? 667 ILE A CG2 1 
ATOM   5156  C  CD1 . ILE A 1 667 ? 232.030 180.982 165.568 1.00 70.79  ? 667 ILE A CD1 1 
ATOM   5157  N  N   . ASP A 1 668 ? 234.793 183.058 165.430 1.00 69.96  ? 668 ASP A N   1 
ATOM   5158  C  CA  . ASP A 1 668 ? 235.068 184.346 164.814 1.00 69.96  ? 668 ASP A CA  1 
ATOM   5159  C  C   . ASP A 1 668 ? 234.014 185.363 165.223 1.00 69.96  ? 668 ASP A C   1 
ATOM   5160  O  O   . ASP A 1 668 ? 232.863 185.011 165.498 1.00 69.96  ? 668 ASP A O   1 
ATOM   5161  C  CB  . ASP A 1 668 ? 235.104 184.210 163.295 1.00 69.96  ? 668 ASP A CB  1 
ATOM   5162  C  CG  . ASP A 1 668 ? 236.284 183.395 162.814 1.00 69.96  ? 668 ASP A CG  1 
ATOM   5163  O  OD1 . ASP A 1 668 ? 237.326 183.394 163.502 1.00 69.96  ? 668 ASP A OD1 1 
ATOM   5164  O  OD2 . ASP A 1 668 ? 236.171 182.754 161.749 1.00 69.96  ? 668 ASP A OD2 1 
ATOM   5165  N  N   . GLY A 1 669 ? 234.410 186.630 165.262 1.00 63.36  ? 669 GLY A N   1 
ATOM   5166  C  CA  . GLY A 1 669 ? 233.531 187.672 165.749 1.00 63.36  ? 669 GLY A CA  1 
ATOM   5167  C  C   . GLY A 1 669 ? 232.680 188.337 164.690 1.00 63.36  ? 669 GLY A C   1 
ATOM   5168  O  O   . GLY A 1 669 ? 232.017 189.338 164.973 1.00 63.36  ? 669 GLY A O   1 
ATOM   5169  N  N   . HIS A 1 670 ? 232.677 187.802 163.471 1.00 65.31  ? 670 HIS A N   1 
ATOM   5170  C  CA  . HIS A 1 670 ? 231.951 188.415 162.365 1.00 65.31  ? 670 HIS A CA  1 
ATOM   5171  C  C   . HIS A 1 670 ? 230.636 187.716 162.051 1.00 65.31  ? 670 HIS A C   1 
ATOM   5172  O  O   . HIS A 1 670 ? 230.056 187.960 160.990 1.00 65.31  ? 670 HIS A O   1 
ATOM   5173  C  CB  . HIS A 1 670 ? 232.829 188.466 161.114 1.00 65.31  ? 670 HIS A CB  1 
ATOM   5174  C  CG  . HIS A 1 670 ? 233.219 187.121 160.591 1.00 65.31  ? 670 HIS A CG  1 
ATOM   5175  N  ND1 . HIS A 1 670 ? 232.415 186.390 159.746 1.00 65.31  ? 670 HIS A ND1 1 
ATOM   5176  C  CD2 . HIS A 1 670 ? 234.335 186.379 160.785 1.00 65.31  ? 670 HIS A CD2 1 
ATOM   5177  C  CE1 . HIS A 1 670 ? 233.015 185.252 159.445 1.00 65.31  ? 670 HIS A CE1 1 
ATOM   5178  N  NE2 . HIS A 1 670 ? 234.182 185.221 160.063 1.00 65.31  ? 670 HIS A NE2 1 
ATOM   5179  N  N   . GLN A 1 671 ? 230.157 186.845 162.935 1.00 60.27  ? 671 GLN A N   1 
ATOM   5180  C  CA  . GLN A 1 671 ? 228.844 186.231 162.793 1.00 60.27  ? 671 GLN A CA  1 
ATOM   5181  C  C   . GLN A 1 671 ? 227.939 186.462 163.991 1.00 60.27  ? 671 GLN A C   1 
ATOM   5182  O  O   . GLN A 1 671 ? 226.723 186.553 163.821 1.00 60.27  ? 671 GLN A O   1 
ATOM   5183  C  CB  . GLN A 1 671 ? 228.978 184.722 162.566 1.00 60.27  ? 671 GLN A CB  1 
ATOM   5184  C  CG  . GLN A 1 671 ? 229.589 184.339 161.234 1.00 60.27  ? 671 GLN A CG  1 
ATOM   5185  C  CD  . GLN A 1 671 ? 229.618 182.838 161.025 1.00 60.27  ? 671 GLN A CD  1 
ATOM   5186  O  OE1 . GLN A 1 671 ? 229.185 182.073 161.886 1.00 60.27  ? 671 GLN A OE1 1 
ATOM   5187  N  NE2 . GLN A 1 671 ? 230.134 182.409 159.879 1.00 60.27  ? 671 GLN A NE2 1 
ATOM   5188  N  N   . LEU A 1 672 ? 228.507 186.535 165.190 1.00 52.99  ? 672 LEU A N   1 
ATOM   5189  C  CA  . LEU A 1 672 ? 227.753 186.855 166.390 1.00 52.99  ? 672 LEU A CA  1 
ATOM   5190  C  C   . LEU A 1 672 ? 227.381 188.331 166.397 1.00 52.99  ? 672 LEU A C   1 
ATOM   5191  O  O   . LEU A 1 672 ? 228.051 189.156 165.769 1.00 52.99  ? 672 LEU A O   1 
ATOM   5192  C  CB  . LEU A 1 672 ? 228.576 186.504 167.624 1.00 52.99  ? 672 LEU A CB  1 
ATOM   5193  C  CG  . LEU A 1 672 ? 227.854 186.437 168.958 1.00 52.99  ? 672 LEU A CG  1 
ATOM   5194  C  CD1 . LEU A 1 672 ? 226.505 185.789 168.791 1.00 52.99  ? 672 LEU A CD1 1 
ATOM   5195  C  CD2 . LEU A 1 672 ? 228.698 185.628 169.907 1.00 52.99  ? 672 LEU A CD2 1 
ATOM   5196  N  N   . THR A 1 673 ? 226.305 188.662 167.106 1.00 49.96  ? 673 THR A N   1 
ATOM   5197  C  CA  . THR A 1 673 ? 225.712 189.995 167.108 1.00 49.96  ? 673 THR A CA  1 
ATOM   5198  C  C   . THR A 1 673 ? 225.172 190.303 168.500 1.00 49.96  ? 673 THR A C   1 
ATOM   5199  O  O   . THR A 1 673 ? 224.894 189.405 169.292 1.00 49.96  ? 673 THR A O   1 
ATOM   5200  C  CB  . THR A 1 673 ? 224.604 190.091 166.053 1.00 49.96  ? 673 THR A CB  1 
ATOM   5201  O  OG1 . THR A 1 673 ? 225.094 189.599 164.800 1.00 49.96  ? 673 THR A OG1 1 
ATOM   5202  C  CG2 . THR A 1 673 ? 224.155 191.527 165.861 1.00 49.96  ? 673 THR A CG2 1 
ATOM   5203  N  N   . VAL A 1 674 ? 225.043 191.589 168.813 1.00 51.46  ? 674 VAL A N   1 
ATOM   5204  C  CA  . VAL A 1 674 ? 224.491 192.021 170.088 1.00 51.46  ? 674 VAL A CA  1 
ATOM   5205  C  C   . VAL A 1 674 ? 223.434 193.081 169.825 1.00 51.46  ? 674 VAL A C   1 
ATOM   5206  O  O   . VAL A 1 674 ? 223.636 194.010 169.042 1.00 51.46  ? 674 VAL A O   1 
ATOM   5207  C  CB  . VAL A 1 674 ? 225.585 192.569 171.030 1.00 51.46  ? 674 VAL A CB  1 
ATOM   5208  C  CG1 . VAL A 1 674 ? 224.976 193.060 172.325 1.00 51.46  ? 674 VAL A CG1 1 
ATOM   5209  C  CG2 . VAL A 1 674 ? 226.623 191.503 171.299 1.00 51.46  ? 674 VAL A CG2 1 
ATOM   5210  N  N   . GLU A 1 675 ? 222.291 192.928 170.480 1.00 51.74  ? 675 GLU A N   1 
ATOM   5211  C  CA  . GLU A 1 675 ? 221.240 193.930 170.472 1.00 51.74  ? 675 GLU A CA  1 
ATOM   5212  C  C   . GLU A 1 675 ? 221.264 194.669 171.797 1.00 51.74  ? 675 GLU A C   1 
ATOM   5213  O  O   . GLU A 1 675 ? 221.517 194.080 172.848 1.00 51.74  ? 675 GLU A O   1 
ATOM   5214  C  CB  . GLU A 1 675 ? 219.867 193.305 170.243 1.00 51.74  ? 675 GLU A CB  1 
ATOM   5215  C  CG  . GLU A 1 675 ? 219.507 193.110 168.787 1.00 51.74  ? 675 GLU A CG  1 
ATOM   5216  C  CD  . GLU A 1 675 ? 220.208 191.924 168.155 1.00 51.74  ? 675 GLU A CD  1 
ATOM   5217  O  OE1 . GLU A 1 675 ? 220.986 191.245 168.855 1.00 51.74  ? 675 GLU A OE1 1 
ATOM   5218  O  OE2 . GLU A 1 675 ? 219.975 191.666 166.955 1.00 51.74  ? 675 GLU A OE2 1 
ATOM   5219  N  N   . ILE A 1 676 ? 221.015 195.972 171.732 1.00 53.35  ? 676 ILE A N   1 
ATOM   5220  C  CA  . ILE A 1 676 ? 221.116 196.846 172.893 1.00 53.35  ? 676 ILE A CA  1 
ATOM   5221  C  C   . ILE A 1 676 ? 220.013 197.888 172.802 1.00 53.35  ? 676 ILE A C   1 
ATOM   5222  O  O   . ILE A 1 676 ? 219.545 198.225 171.713 1.00 53.35  ? 676 ILE A O   1 
ATOM   5223  C  CB  . ILE A 1 676 ? 222.521 197.484 172.976 1.00 53.35  ? 676 ILE A CB  1 
ATOM   5224  C  CG1 . ILE A 1 676 ? 222.823 198.256 171.695 1.00 53.35  ? 676 ILE A CG1 1 
ATOM   5225  C  CG2 . ILE A 1 676 ? 223.595 196.446 173.226 1.00 53.35  ? 676 ILE A CG2 1 
ATOM   5226  C  CD1 . ILE A 1 676 ? 224.108 199.025 171.754 1.00 53.35  ? 676 ILE A CD1 1 
ATOM   5227  N  N   . THR A 1 677 ? 219.603 198.392 173.958 1.00 68.38  ? 677 THR A N   1 
ATOM   5228  C  CA  . THR A 1 677 ? 218.511 199.342 174.083 1.00 68.38  ? 677 THR A CA  1 
ATOM   5229  C  C   . THR A 1 677 ? 219.026 200.626 174.717 1.00 68.38  ? 677 THR A C   1 
ATOM   5230  O  O   . THR A 1 677 ? 219.926 200.599 175.560 1.00 68.38  ? 677 THR A O   1 
ATOM   5231  C  CB  . THR A 1 677 ? 217.375 198.758 174.931 1.00 68.38  ? 677 THR A CB  1 
ATOM   5232  O  OG1 . THR A 1 677 ? 216.936 197.521 174.357 1.00 68.38  ? 677 THR A OG1 1 
ATOM   5233  C  CG2 . THR A 1 677 ? 216.196 199.719 175.016 1.00 68.38  ? 677 THR A CG2 1 
ATOM   5234  N  N   . GLU A 1 678 ? 218.455 201.756 174.298 1.00 76.67  ? 678 GLU A N   1 
ATOM   5235  C  CA  . GLU A 1 678 ? 218.908 203.037 174.823 1.00 76.67  ? 678 GLU A CA  1 
ATOM   5236  C  C   . GLU A 1 678 ? 218.671 203.145 176.322 1.00 76.67  ? 678 GLU A C   1 
ATOM   5237  O  O   . GLU A 1 678 ? 219.417 203.845 177.016 1.00 76.67  ? 678 GLU A O   1 
ATOM   5238  C  CB  . GLU A 1 678 ? 218.213 204.183 174.088 1.00 76.67  ? 678 GLU A CB  1 
ATOM   5239  C  CG  . GLU A 1 678 ? 216.736 204.343 174.414 1.00 76.67  ? 678 GLU A CG  1 
ATOM   5240  C  CD  . GLU A 1 678 ? 215.845 203.484 173.539 1.00 76.67  ? 678 GLU A CD  1 
ATOM   5241  O  OE1 . GLU A 1 678 ? 216.367 202.557 172.885 1.00 76.67  ? 678 GLU A OE1 1 
ATOM   5242  O  OE2 . GLU A 1 678 ? 214.622 203.735 173.507 1.00 76.67  ? 678 GLU A OE2 1 
ATOM   5243  N  N   . SER A 1 679 ? 217.648 202.462 176.841 1.00 84.96  ? 679 SER A N   1 
ATOM   5244  C  CA  . SER A 1 679 ? 217.367 202.539 178.270 1.00 84.96  ? 679 SER A CA  1 
ATOM   5245  C  C   . SER A 1 679 ? 218.528 202.007 179.094 1.00 84.96  ? 679 SER A C   1 
ATOM   5246  O  O   . SER A 1 679 ? 218.923 202.631 180.085 1.00 84.96  ? 679 SER A O   1 
ATOM   5247  C  CB  . SER A 1 679 ? 216.085 201.773 178.598 1.00 84.96  ? 679 SER A CB  1 
ATOM   5248  O  OG  . SER A 1 679 ? 216.201 200.407 178.241 1.00 84.96  ? 679 SER A OG  1 
ATOM   5249  N  N   . MET A 1 680 ? 219.088 200.864 178.702 1.00 84.66  ? 680 MET A N   1 
ATOM   5250  C  CA  . MET A 1 680 ? 220.293 200.346 179.332 1.00 84.66  ? 680 MET A CA  1 
ATOM   5251  C  C   . MET A 1 680 ? 221.550 201.088 178.904 1.00 84.66  ? 680 MET A C   1 
ATOM   5252  O  O   . MET A 1 680 ? 222.513 201.139 179.677 1.00 84.66  ? 680 MET A O   1 
ATOM   5253  C  CB  . MET A 1 680 ? 220.461 198.855 179.023 1.00 84.66  ? 680 MET A CB  1 
ATOM   5254  C  CG  . MET A 1 680 ? 219.361 197.973 179.587 1.00 84.66  ? 680 MET A CG  1 
ATOM   5255  S  SD  . MET A 1 680 ? 219.710 196.227 179.319 1.00 84.66  ? 680 MET A SD  1 
ATOM   5256  C  CE  . MET A 1 680 ? 219.790 196.191 177.532 1.00 84.66  ? 680 MET A CE  1 
ATOM   5257  N  N   . MET A 1 681 ? 221.563 201.655 177.698 1.00 81.67  ? 681 MET A N   1 
ATOM   5258  C  CA  . MET A 1 681 ? 222.717 202.400 177.216 1.00 81.67  ? 681 MET A CA  1 
ATOM   5259  C  C   . MET A 1 681 ? 222.965 203.687 177.985 1.00 81.67  ? 681 MET A C   1 
ATOM   5260  O  O   . MET A 1 681 ? 224.126 204.051 178.196 1.00 81.67  ? 681 MET A O   1 
ATOM   5261  C  CB  . MET A 1 681 ? 222.546 202.741 175.739 1.00 81.67  ? 681 MET A CB  1 
ATOM   5262  C  CG  . MET A 1 681 ? 223.745 203.445 175.146 1.00 81.67  ? 681 MET A CG  1 
ATOM   5263  S  SD  . MET A 1 681 ? 223.463 203.911 173.435 1.00 81.67  ? 681 MET A SD  1 
ATOM   5264  C  CE  . MET A 1 681 ? 223.528 202.314 172.656 1.00 81.67  ? 681 MET A CE  1 
ATOM   5265  N  N   . MET A 1 682 ? 221.913 204.387 178.398 1.00 90.03  ? 682 MET A N   1 
ATOM   5266  C  CA  . MET A 1 682 ? 222.056 205.687 179.040 1.00 90.03  ? 682 MET A CA  1 
ATOM   5267  C  C   . MET A 1 682 ? 221.795 205.608 180.540 1.00 90.03  ? 682 MET A C   1 
ATOM   5268  O  O   . MET A 1 682 ? 221.469 206.615 181.173 1.00 90.03  ? 682 MET A O   1 
ATOM   5269  C  CB  . MET A 1 682 ? 221.138 206.716 178.383 1.00 90.03  ? 682 MET A CB  1 
ATOM   5270  C  CG  . MET A 1 682 ? 221.441 206.951 176.911 1.00 90.03  ? 682 MET A CG  1 
ATOM   5271  S  SD  . MET A 1 682 ? 223.190 206.773 176.498 1.00 90.03  ? 682 MET A SD  1 
ATOM   5272  C  CE  . MET A 1 682 ? 223.883 208.242 177.254 1.00 90.03  ? 682 MET A CE  1 
ATOM   5273  N  N   . GLU A 1 683 ? 221.928 204.413 181.121 1.00 92.14  ? 683 GLU A N   1 
ATOM   5274  C  CA  . GLU A 1 683 ? 221.879 204.294 182.574 1.00 92.14  ? 683 GLU A CA  1 
ATOM   5275  C  C   . GLU A 1 683 ? 222.999 205.100 183.216 1.00 92.14  ? 683 GLU A C   1 
ATOM   5276  O  O   . GLU A 1 683 ? 222.785 205.795 184.217 1.00 92.14  ? 683 GLU A O   1 
ATOM   5277  C  CB  . GLU A 1 683 ? 221.971 202.826 182.989 1.00 92.14  ? 683 GLU A CB  1 
ATOM   5278  C  CG  . GLU A 1 683 ? 220.748 201.997 182.642 1.00 92.14  ? 683 GLU A CG  1 
ATOM   5279  C  CD  . GLU A 1 683 ? 220.742 200.650 183.339 1.00 92.14  ? 683 GLU A CD  1 
ATOM   5280  O  OE1 . GLU A 1 683 ? 221.789 200.265 183.901 1.00 92.14  ? 683 GLU A OE1 1 
ATOM   5281  O  OE2 . GLU A 1 683 ? 219.691 199.976 183.323 1.00 92.14  ? 683 GLU A OE2 1 
ATOM   5282  N  N   . HIS A 1 684 ? 224.201 205.016 182.652 1.00 92.84  ? 684 HIS A N   1 
ATOM   5283  C  CA  . HIS A 1 684 ? 225.315 205.867 183.060 1.00 92.84  ? 684 HIS A CA  1 
ATOM   5284  C  C   . HIS A 1 684 ? 226.024 206.307 181.787 1.00 92.84  ? 684 HIS A C   1 
ATOM   5285  O  O   . HIS A 1 684 ? 226.378 205.469 180.952 1.00 92.84  ? 684 HIS A O   1 
ATOM   5286  C  CB  . HIS A 1 684 ? 226.263 205.130 184.000 1.00 92.84  ? 684 HIS A CB  1 
ATOM   5287  C  CG  . HIS A 1 684 ? 227.195 206.032 184.748 1.00 92.84  ? 684 HIS A CG  1 
ATOM   5288  N  ND1 . HIS A 1 684 ? 228.341 205.574 185.362 1.00 92.84  ? 684 HIS A ND1 1 
ATOM   5289  C  CD2 . HIS A 1 684 ? 227.149 207.364 184.985 1.00 92.84  ? 684 HIS A CD2 1 
ATOM   5290  C  CE1 . HIS A 1 684 ? 228.962 206.585 185.942 1.00 92.84  ? 684 HIS A CE1 1 
ATOM   5291  N  NE2 . HIS A 1 684 ? 228.259 207.683 185.728 1.00 92.84  ? 684 HIS A NE2 1 
ATOM   5292  N  N   . ASP A 1 685 ? 226.230 207.615 181.638 1.00 95.50  ? 685 ASP A N   1 
ATOM   5293  C  CA  . ASP A 1 685 ? 226.769 208.146 180.391 1.00 95.50  ? 685 ASP A CA  1 
ATOM   5294  C  C   . ASP A 1 685 ? 228.270 207.925 180.256 1.00 95.50  ? 685 ASP A C   1 
ATOM   5295  O  O   . ASP A 1 685 ? 228.899 208.554 179.398 1.00 95.50  ? 685 ASP A O   1 
ATOM   5296  C  CB  . ASP A 1 685 ? 226.453 209.639 180.281 1.00 95.50  ? 685 ASP A CB  1 
ATOM   5297  C  CG  . ASP A 1 685 ? 224.966 209.912 180.151 1.00 95.50  ? 685 ASP A CG  1 
ATOM   5298  O  OD1 . ASP A 1 685 ? 224.163 209.023 180.505 1.00 95.50  ? 685 ASP A OD1 1 
ATOM   5299  O  OD2 . ASP A 1 685 ? 224.601 211.016 179.696 1.00 95.50  ? 685 ASP A OD2 1 
ATOM   5300  N  N   . THR A 1 686 ? 228.863 207.055 181.078 1.00 95.13  ? 686 THR A N   1 
ATOM   5301  C  CA  . THR A 1 686 ? 230.319 206.970 181.119 1.00 95.13  ? 686 THR A CA  1 
ATOM   5302  C  C   . THR A 1 686 ? 230.831 205.638 180.579 1.00 95.13  ? 686 THR A C   1 
ATOM   5303  O  O   . THR A 1 686 ? 231.656 205.610 179.659 1.00 95.13  ? 686 THR A O   1 
ATOM   5304  C  CB  . THR A 1 686 ? 230.813 207.190 182.550 1.00 95.13  ? 686 THR A CB  1 
ATOM   5305  O  OG1 . THR A 1 686 ? 230.118 208.299 183.133 1.00 95.13  ? 686 THR A OG1 1 
ATOM   5306  C  CG2 . THR A 1 686 ? 232.308 207.474 182.559 1.00 95.13  ? 686 THR A CG2 1 
ATOM   5307  N  N   . GLU A 1 687 ? 230.361 204.522 181.135 1.00 91.04  ? 687 GLU A N   1 
ATOM   5308  C  CA  . GLU A 1 687 ? 231.079 203.261 180.997 1.00 91.04  ? 687 GLU A CA  1 
ATOM   5309  C  C   . GLU A 1 687 ? 230.474 202.275 180.012 1.00 91.04  ? 687 GLU A C   1 
ATOM   5310  O  O   . GLU A 1 687 ? 231.214 201.457 179.464 1.00 91.04  ? 687 GLU A O   1 
ATOM   5311  C  CB  . GLU A 1 687 ? 231.202 202.573 182.362 1.00 91.04  ? 687 GLU A CB  1 
ATOM   5312  C  CG  . GLU A 1 687 ? 229.919 201.931 182.859 1.00 91.04  ? 687 GLU A CG  1 
ATOM   5313  C  CD  . GLU A 1 687 ? 229.022 202.913 183.580 1.00 91.04  ? 687 GLU A CD  1 
ATOM   5314  O  OE1 . GLU A 1 687 ? 229.219 204.134 183.410 1.00 91.04  ? 687 GLU A OE1 1 
ATOM   5315  O  OE2 . GLU A 1 687 ? 228.120 202.464 184.318 1.00 91.04  ? 687 GLU A OE2 1 
ATOM   5316  N  N   . ILE A 1 688 ? 229.162 202.310 179.774 1.00 90.61  ? 688 ILE A N   1 
ATOM   5317  C  CA  . ILE A 1 688 ? 228.536 201.271 178.955 1.00 90.61  ? 688 ILE A CA  1 
ATOM   5318  C  C   . ILE A 1 688 ? 229.075 201.312 177.531 1.00 90.61  ? 688 ILE A C   1 
ATOM   5319  O  O   . ILE A 1 688 ? 229.512 200.293 176.982 1.00 90.61  ? 688 ILE A O   1 
ATOM   5320  C  CB  . ILE A 1 688 ? 227.002 201.401 178.983 1.00 90.61  ? 688 ILE A CB  1 
ATOM   5321  C  CG1 . ILE A 1 688 ? 226.455 201.123 180.388 1.00 90.61  ? 688 ILE A CG1 1 
ATOM   5322  C  CG2 . ILE A 1 688 ? 226.369 200.462 177.967 1.00 90.61  ? 688 ILE A CG2 1 
ATOM   5323  C  CD1 . ILE A 1 688 ? 226.352 202.335 181.282 1.00 90.61  ? 688 ILE A CD1 1 
ATOM   5324  N  N   . PHE A 1 689 ? 229.063 202.494 176.914 1.00 93.34  ? 689 PHE A N   1 
ATOM   5325  C  CA  . PHE A 1 689 ? 229.550 202.583 175.544 1.00 93.34  ? 689 PHE A CA  1 
ATOM   5326  C  C   . PHE A 1 689 ? 231.046 202.319 175.476 1.00 93.34  ? 689 PHE A C   1 
ATOM   5327  O  O   . PHE A 1 689 ? 231.530 201.753 174.492 1.00 93.34  ? 689 PHE A O   1 
ATOM   5328  C  CB  . PHE A 1 689 ? 229.198 203.944 174.935 1.00 93.34  ? 689 PHE A CB  1 
ATOM   5329  C  CG  . PHE A 1 689 ? 229.977 205.095 175.507 1.00 93.34  ? 689 PHE A CG  1 
ATOM   5330  C  CD1 . PHE A 1 689 ? 231.133 205.543 174.889 1.00 93.34  ? 689 PHE A CD1 1 
ATOM   5331  C  CD2 . PHE A 1 689 ? 229.544 205.739 176.654 1.00 93.34  ? 689 PHE A CD2 1 
ATOM   5332  C  CE1 . PHE A 1 689 ? 231.848 206.605 175.409 1.00 93.34  ? 689 PHE A CE1 1 
ATOM   5333  C  CE2 . PHE A 1 689 ? 230.254 206.802 177.177 1.00 93.34  ? 689 PHE A CE2 1 
ATOM   5334  C  CZ  . PHE A 1 689 ? 231.407 207.235 176.555 1.00 93.34  ? 689 PHE A CZ  1 
ATOM   5335  N  N   . LYS A 1 690 ? 231.789 202.690 176.520 1.00 94.47  ? 690 LYS A N   1 
ATOM   5336  C  CA  . LYS A 1 690 ? 233.209 202.360 176.554 1.00 94.47  ? 690 LYS A CA  1 
ATOM   5337  C  C   . LYS A 1 690 ? 233.417 200.852 176.550 1.00 94.47  ? 690 LYS A C   1 
ATOM   5338  O  O   . LYS A 1 690 ? 234.315 200.343 175.870 1.00 94.47  ? 690 LYS A O   1 
ATOM   5339  C  CB  . LYS A 1 690 ? 233.871 202.996 177.776 1.00 94.47  ? 690 LYS A CB  1 
ATOM   5340  C  CG  . LYS A 1 690 ? 233.978 204.510 177.706 1.00 94.47  ? 690 LYS A CG  1 
ATOM   5341  C  CD  . LYS A 1 690 ? 234.787 205.060 178.870 1.00 94.47  ? 690 LYS A CD  1 
ATOM   5342  C  CE  . LYS A 1 690 ? 235.041 206.551 178.713 1.00 94.47  ? 690 LYS A CE  1 
ATOM   5343  N  NZ  . LYS A 1 690 ? 233.785 207.344 178.810 1.00 94.47  ? 690 LYS A NZ  1 
ATOM   5344  N  N   . ARG A 1 691 ? 232.595 200.120 177.304 1.00 89.75  ? 691 ARG A N   1 
ATOM   5345  C  CA  . ARG A 1 691 ? 232.684 198.666 177.277 1.00 89.75  ? 691 ARG A CA  1 
ATOM   5346  C  C   . ARG A 1 691 ? 232.338 198.134 175.894 1.00 89.75  ? 691 ARG A C   1 
ATOM   5347  O  O   . ARG A 1 691 ? 233.024 197.254 175.362 1.00 89.75  ? 691 ARG A O   1 
ATOM   5348  C  CB  . ARG A 1 691 ? 231.763 198.059 178.335 1.00 89.75  ? 691 ARG A CB  1 
ATOM   5349  C  CG  . ARG A 1 691 ? 232.072 198.500 179.754 1.00 89.75  ? 691 ARG A CG  1 
ATOM   5350  C  CD  . ARG A 1 691 ? 233.447 198.042 180.194 1.00 89.75  ? 691 ARG A CD  1 
ATOM   5351  N  NE  . ARG A 1 691 ? 233.728 198.426 181.571 1.00 89.75  ? 691 ARG A NE  1 
ATOM   5352  C  CZ  . ARG A 1 691 ? 234.894 198.245 182.178 1.00 89.75  ? 691 ARG A CZ  1 
ATOM   5353  N  NH1 . ARG A 1 691 ? 235.917 197.684 181.555 1.00 89.75  ? 691 ARG A NH1 1 
ATOM   5354  N  NH2 . ARG A 1 691 ? 235.036 198.636 183.441 1.00 89.75  ? 691 ARG A NH2 1 
ATOM   5355  N  N   . ILE A 1 692 ? 231.281 198.679 175.289 1.00 86.74  ? 692 ILE A N   1 
ATOM   5356  C  CA  . ILE A 1 692 ? 230.874 198.243 173.957 1.00 86.74  ? 692 ILE A CA  1 
ATOM   5357  C  C   . ILE A 1 692 ? 231.948 198.558 172.922 1.00 86.74  ? 692 ILE A C   1 
ATOM   5358  O  O   . ILE A 1 692 ? 231.984 197.932 171.858 1.00 86.74  ? 692 ILE A O   1 
ATOM   5359  C  CB  . ILE A 1 692 ? 229.512 198.877 173.584 1.00 86.74  ? 692 ILE A CB  1 
ATOM   5360  C  CG1 . ILE A 1 692 ? 228.443 198.472 174.596 1.00 86.74  ? 692 ILE A CG1 1 
ATOM   5361  C  CG2 . ILE A 1 692 ? 229.059 198.449 172.200 1.00 86.74  ? 692 ILE A CG2 1 
ATOM   5362  C  CD1 . ILE A 1 692 ? 228.028 197.024 174.495 1.00 86.74  ? 692 ILE A CD1 1 
ATOM   5363  N  N   . GLN A 1 693 ? 232.832 199.516 173.212 1.00 87.65  ? 693 GLN A N   1 
ATOM   5364  C  CA  . GLN A 1 693 ? 233.902 199.832 172.270 1.00 87.65  ? 693 GLN A CA  1 
ATOM   5365  C  C   . GLN A 1 693 ? 234.801 198.630 172.027 1.00 87.65  ? 693 GLN A C   1 
ATOM   5366  O  O   . GLN A 1 693 ? 235.200 198.367 170.888 1.00 87.65  ? 693 GLN A O   1 
ATOM   5367  C  CB  . GLN A 1 693 ? 234.731 201.013 172.772 1.00 87.65  ? 693 GLN A CB  1 
ATOM   5368  C  CG  . GLN A 1 693 ? 233.988 202.327 172.773 1.00 87.65  ? 693 GLN A CG  1 
ATOM   5369  C  CD  . GLN A 1 693 ? 233.489 202.702 171.397 1.00 87.65  ? 693 GLN A CD  1 
ATOM   5370  O  OE1 . GLN A 1 693 ? 232.291 202.646 171.127 1.00 87.65  ? 693 GLN A OE1 1 
ATOM   5371  N  NE2 . GLN A 1 693 ? 234.406 203.084 170.515 1.00 87.65  ? 693 GLN A NE2 1 
ATOM   5372  N  N   . ILE A 1 694 ? 235.142 197.895 173.086 1.00 83.72  ? 694 ILE A N   1 
ATOM   5373  C  CA  . ILE A 1 694 ? 236.010 196.730 172.929 1.00 83.72  ? 694 ILE A CA  1 
ATOM   5374  C  C   . ILE A 1 694 ? 235.347 195.692 172.033 1.00 83.72  ? 694 ILE A C   1 
ATOM   5375  O  O   . ILE A 1 694 ? 235.973 195.136 171.124 1.00 83.72  ? 694 ILE A O   1 
ATOM   5376  C  CB  . ILE A 1 694 ? 236.371 196.142 174.304 1.00 83.72  ? 694 ILE A CB  1 
ATOM   5377  C  CG1 . ILE A 1 694 ? 236.920 197.235 175.222 1.00 83.72  ? 694 ILE A CG1 1 
ATOM   5378  C  CG2 . ILE A 1 694 ? 237.379 195.015 174.153 1.00 83.72  ? 694 ILE A CG2 1 
ATOM   5379  C  CD1 . ILE A 1 694 ? 238.143 197.937 174.672 1.00 83.72  ? 694 ILE A CD1 1 
ATOM   5380  N  N   . LEU A 1 695 ? 234.062 195.426 172.268 1.00 80.63  ? 695 LEU A N   1 
ATOM   5381  C  CA  . LEU A 1 695 ? 233.350 194.454 171.447 1.00 80.63  ? 695 LEU A CA  1 
ATOM   5382  C  C   . LEU A 1 695 ? 233.250 194.917 170.000 1.00 80.63  ? 695 LEU A C   1 
ATOM   5383  O  O   . LEU A 1 695 ? 233.425 194.122 169.068 1.00 80.63  ? 695 LEU A O   1 
ATOM   5384  C  CB  . LEU A 1 695 ? 231.960 194.208 172.026 1.00 80.63  ? 695 LEU A CB  1 
ATOM   5385  C  CG  . LEU A 1 695 ? 231.161 193.083 171.378 1.00 80.63  ? 695 LEU A CG  1 
ATOM   5386  C  CD1 . LEU A 1 695 ? 231.878 191.757 171.553 1.00 80.63  ? 695 LEU A CD1 1 
ATOM   5387  C  CD2 . LEU A 1 695 ? 229.777 193.030 171.983 1.00 80.63  ? 695 LEU A CD2 1 
ATOM   5388  N  N   . ARG A 1 696 ? 232.969 196.204 169.792 1.00 78.11  ? 696 ARG A N   1 
ATOM   5389  C  CA  . ARG A 1 696 ? 232.855 196.724 168.436 1.00 78.11  ? 696 ARG A CA  1 
ATOM   5390  C  C   . ARG A 1 696 ? 234.186 196.630 167.707 1.00 78.11  ? 696 ARG A C   1 
ATOM   5391  O  O   . ARG A 1 696 ? 234.227 196.343 166.505 1.00 78.11  ? 696 ARG A O   1 
ATOM   5392  C  CB  . ARG A 1 696 ? 232.351 198.164 168.471 1.00 78.11  ? 696 ARG A CB  1 
ATOM   5393  C  CG  . ARG A 1 696 ? 232.215 198.802 167.105 1.00 78.11  ? 696 ARG A CG  1 
ATOM   5394  C  CD  . ARG A 1 696 ? 231.166 198.094 166.273 1.00 78.11  ? 696 ARG A CD  1 
ATOM   5395  N  NE  . ARG A 1 696 ? 231.747 197.038 165.455 1.00 78.11  ? 696 ARG A NE  1 
ATOM   5396  C  CZ  . ARG A 1 696 ? 231.070 196.320 164.572 1.00 78.11  ? 696 ARG A CZ  1 
ATOM   5397  N  NH1 . ARG A 1 696 ? 229.781 196.526 164.355 1.00 78.11  ? 696 ARG A NH1 1 
ATOM   5398  N  NH2 . ARG A 1 696 ? 231.701 195.370 163.888 1.00 78.11  ? 696 ARG A NH2 1 
ATOM   5399  N  N   . ASP A 1 697 ? 235.288 196.870 168.421 1.00 84.90  ? 697 ASP A N   1 
ATOM   5400  C  CA  . ASP A 1 697 ? 236.610 196.641 167.848 1.00 84.90  ? 697 ASP A CA  1 
ATOM   5401  C  C   . ASP A 1 697 ? 236.817 195.166 167.530 1.00 84.90  ? 697 ASP A C   1 
ATOM   5402  O  O   . ASP A 1 697 ? 237.461 194.822 166.532 1.00 84.90  ? 697 ASP A O   1 
ATOM   5403  C  CB  . ASP A 1 697 ? 237.690 197.143 168.806 1.00 84.90  ? 697 ASP A CB  1 
ATOM   5404  C  CG  . ASP A 1 697 ? 237.761 198.656 168.862 1.00 84.90  ? 697 ASP A CG  1 
ATOM   5405  O  OD1 . ASP A 1 697 ? 237.189 199.312 167.967 1.00 84.90  ? 697 ASP A OD1 1 
ATOM   5406  O  OD2 . ASP A 1 697 ? 238.387 199.189 169.802 1.00 84.90  ? 697 ASP A OD2 1 
ATOM   5407  N  N   . MET A 1 698 ? 236.287 194.279 168.377 1.00 77.15  ? 698 MET A N   1 
ATOM   5408  C  CA  . MET A 1 698 ? 236.365 192.851 168.089 1.00 77.15  ? 698 MET A CA  1 
ATOM   5409  C  C   . MET A 1 698 ? 235.658 192.511 166.787 1.00 77.15  ? 698 MET A C   1 
ATOM   5410  O  O   . MET A 1 698 ? 236.148 191.682 166.013 1.00 77.15  ? 698 MET A O   1 
ATOM   5411  C  CB  . MET A 1 698 ? 235.772 192.040 169.238 1.00 77.15  ? 698 MET A CB  1 
ATOM   5412  C  CG  . MET A 1 698 ? 236.565 192.108 170.523 1.00 77.15  ? 698 MET A CG  1 
ATOM   5413  S  SD  . MET A 1 698 ? 238.220 191.444 170.306 1.00 77.15  ? 698 MET A SD  1 
ATOM   5414  C  CE  . MET A 1 698 ? 237.841 189.712 170.071 1.00 77.15  ? 698 MET A CE  1 
ATOM   5415  N  N   . GLY A 1 699 ? 234.514 193.133 166.530 1.00 73.29  ? 699 GLY A N   1 
ATOM   5416  C  CA  . GLY A 1 699 ? 233.807 192.963 165.275 1.00 73.29  ? 699 GLY A CA  1 
ATOM   5417  C  C   . GLY A 1 699 ? 232.419 192.374 165.396 1.00 73.29  ? 699 GLY A C   1 
ATOM   5418  O  O   . GLY A 1 699 ? 231.738 192.229 164.373 1.00 73.29  ? 699 GLY A O   1 
ATOM   5419  N  N   . VAL A 1 700 ? 231.981 192.018 166.605 1.00 66.23  ? 700 VAL A N   1 
ATOM   5420  C  CA  . VAL A 1 700 ? 230.615 191.555 166.790 1.00 66.23  ? 700 VAL A CA  1 
ATOM   5421  C  C   . VAL A 1 700 ? 229.659 192.682 166.459 1.00 66.23  ? 700 VAL A C   1 
ATOM   5422  O  O   . VAL A 1 700 ? 229.833 193.819 166.908 1.00 66.23  ? 700 VAL A O   1 
ATOM   5423  C  CB  . VAL A 1 700 ? 230.420 191.053 168.231 1.00 66.23  ? 700 VAL A CB  1 
ATOM   5424  C  CG1 . VAL A 1 700 ? 228.961 190.757 168.503 1.00 66.23  ? 700 VAL A CG1 1 
ATOM   5425  C  CG2 . VAL A 1 700 ? 231.274 189.819 168.478 1.00 66.23  ? 700 VAL A CG2 1 
ATOM   5426  N  N   . GLY A 1 701 ? 228.647 192.374 165.656 1.00 59.07  ? 701 GLY A N   1 
ATOM   5427  C  CA  . GLY A 1 701 ? 227.714 193.397 165.230 1.00 59.07  ? 701 GLY A CA  1 
ATOM   5428  C  C   . GLY A 1 701 ? 226.926 193.975 166.389 1.00 59.07  ? 701 GLY A C   1 
ATOM   5429  O  O   . GLY A 1 701 ? 226.646 193.306 167.382 1.00 59.07  ? 701 GLY A O   1 
ATOM   5430  N  N   . LEU A 1 702 ? 226.569 195.247 166.257 1.00 54.72  ? 702 LEU A N   1 
ATOM   5431  C  CA  . LEU A 1 702 ? 225.762 195.950 167.246 1.00 54.72  ? 702 LEU A CA  1 
ATOM   5432  C  C   . LEU A 1 702 ? 224.465 196.393 166.587 1.00 54.72  ? 702 LEU A C   1 
ATOM   5433  O  O   . LEU A 1 702 ? 224.412 197.462 165.973 1.00 54.72  ? 702 LEU A O   1 
ATOM   5434  C  CB  . LEU A 1 702 ? 226.504 197.155 167.816 1.00 54.72  ? 702 LEU A CB  1 
ATOM   5435  C  CG  . LEU A 1 702 ? 227.327 196.996 169.090 1.00 54.72  ? 702 LEU A CG  1 
ATOM   5436  C  CD1 . LEU A 1 702 ? 226.424 196.677 170.261 1.00 54.72  ? 702 LEU A CD1 1 
ATOM   5437  C  CD2 . LEU A 1 702 ? 228.386 195.924 168.917 1.00 54.72  ? 702 LEU A CD2 1 
ATOM   5438  N  N   . SER A 1 703 ? 223.421 195.588 166.718 1.00 48.69  ? 703 SER A N   1 
ATOM   5439  C  CA  . SER A 1 703 ? 222.103 196.025 166.307 1.00 48.69  ? 703 SER A CA  1 
ATOM   5440  C  C   . SER A 1 703 ? 221.561 197.006 167.333 1.00 48.69  ? 703 SER A C   1 
ATOM   5441  O  O   . SER A 1 703 ? 222.177 197.262 168.368 1.00 48.69  ? 703 SER A O   1 
ATOM   5442  C  CB  . SER A 1 703 ? 221.163 194.839 166.144 1.00 48.69  ? 703 SER A CB  1 
ATOM   5443  O  OG  . SER A 1 703 ? 219.947 195.247 165.549 1.00 48.69  ? 703 SER A OG  1 
ATOM   5444  N  N   . VAL A 1 704 ? 220.390 197.572 167.052 1.00 49.04  ? 704 VAL A N   1 
ATOM   5445  C  CA  . VAL A 1 704 ? 219.721 198.437 168.011 1.00 49.04  ? 704 VAL A CA  1 
ATOM   5446  C  C   . VAL A 1 704 ? 218.232 198.356 167.745 1.00 49.04  ? 704 VAL A C   1 
ATOM   5447  O  O   . VAL A 1 704 ? 217.795 197.849 166.715 1.00 49.04  ? 704 VAL A O   1 
ATOM   5448  C  CB  . VAL A 1 704 ? 220.231 199.898 167.932 1.00 49.04  ? 704 VAL A CB  1 
ATOM   5449  C  CG1 . VAL A 1 704 ? 219.604 200.621 166.776 1.00 49.04  ? 704 VAL A CG1 1 
ATOM   5450  C  CG2 . VAL A 1 704 ? 219.987 200.628 169.238 1.00 49.04  ? 704 VAL A CG2 1 
ATOM   5451  N  N   . ASP A 1 705 ? 217.454 198.870 168.680 1.00 61.94  ? 705 ASP A N   1 
ATOM   5452  C  CA  . ASP A 1 705 ? 216.014 198.952 168.714 1.00 61.94  ? 705 ASP A CA  1 
ATOM   5453  C  C   . ASP A 1 705 ? 215.680 200.435 168.652 1.00 61.94  ? 705 ASP A C   1 
ATOM   5454  O  O   . ASP A 1 705 ? 216.481 201.226 168.141 1.00 61.94  ? 705 ASP A O   1 
ATOM   5455  C  CB  . ASP A 1 705 ? 215.465 198.240 169.951 1.00 61.94  ? 705 ASP A CB  1 
ATOM   5456  C  CG  . ASP A 1 705 ? 216.085 198.736 171.237 1.00 61.94  ? 705 ASP A CG  1 
ATOM   5457  O  OD1 . ASP A 1 705 ? 216.992 199.593 171.185 1.00 61.94  ? 705 ASP A OD1 1 
ATOM   5458  O  OD2 . ASP A 1 705 ? 215.659 198.256 172.306 1.00 61.94  ? 705 ASP A OD2 1 
ATOM   5459  N  N   . ASP A 1 706 ? 214.474 200.796 169.087 1.00 71.81  ? 706 ASP A N   1 
ATOM   5460  C  CA  . ASP A 1 706 ? 213.984 202.167 168.996 1.00 71.81  ? 706 ASP A CA  1 
ATOM   5461  C  C   . ASP A 1 706 ? 215.106 203.177 169.194 1.00 71.81  ? 706 ASP A C   1 
ATOM   5462  O  O   . ASP A 1 706 ? 215.946 203.025 170.086 1.00 71.81  ? 706 ASP A O   1 
ATOM   5463  C  CB  . ASP A 1 706 ? 212.875 202.404 170.023 1.00 71.81  ? 706 ASP A CB  1 
ATOM   5464  C  CG  . ASP A 1 706 ? 211.789 201.349 169.961 1.00 71.81  ? 706 ASP A CG  1 
ATOM   5465  O  OD1 . ASP A 1 706 ? 211.652 200.697 168.904 1.00 71.81  ? 706 ASP A OD1 1 
ATOM   5466  O  OD2 . ASP A 1 706 ? 211.073 201.171 170.968 1.00 71.81  ? 706 ASP A OD2 1 
ATOM   5467  N  N   . PHE A 1 707 ? 215.119 204.202 168.347 1.00 74.20  ? 707 PHE A N   1 
ATOM   5468  C  CA  . PHE A 1 707 ? 216.311 204.988 168.069 1.00 74.20  ? 707 PHE A CA  1 
ATOM   5469  C  C   . PHE A 1 707 ? 216.831 205.681 169.327 1.00 74.20  ? 707 PHE A C   1 
ATOM   5470  O  O   . PHE A 1 707 ? 216.160 205.749 170.359 1.00 74.20  ? 707 PHE A O   1 
ATOM   5471  C  CB  . PHE A 1 707 ? 215.995 206.017 166.985 1.00 74.20  ? 707 PHE A CB  1 
ATOM   5472  C  CG  . PHE A 1 707 ? 217.202 206.582 166.314 1.00 74.20  ? 707 PHE A CG  1 
ATOM   5473  C  CD1 . PHE A 1 707 ? 217.886 205.840 165.366 1.00 74.20  ? 707 PHE A CD1 1 
ATOM   5474  C  CD2 . PHE A 1 707 ? 217.648 207.854 166.618 1.00 74.20  ? 707 PHE A CD2 1 
ATOM   5475  C  CE1 . PHE A 1 707 ? 218.998 206.354 164.740 1.00 74.20  ? 707 PHE A CE1 1 
ATOM   5476  C  CE2 . PHE A 1 707 ? 218.758 208.371 165.996 1.00 74.20  ? 707 PHE A CE2 1 
ATOM   5477  C  CZ  . PHE A 1 707 ? 219.435 207.620 165.055 1.00 74.20  ? 707 PHE A CZ  1 
ATOM   5478  N  N   . GLY A 1 708 ? 218.048 206.199 169.230 1.00 73.59  ? 708 GLY A N   1 
ATOM   5479  C  CA  . GLY A 1 708 ? 218.652 206.894 170.349 1.00 73.59  ? 708 GLY A CA  1 
ATOM   5480  C  C   . GLY A 1 708 ? 218.025 208.255 170.580 1.00 73.59  ? 708 GLY A C   1 
ATOM   5481  O  O   . GLY A 1 708 ? 217.089 208.679 169.904 1.00 73.59  ? 708 GLY A O   1 
ATOM   5482  N  N   . THR A 1 709 ? 218.562 208.955 171.579 1.00 76.69  ? 709 THR A N   1 
ATOM   5483  C  CA  . THR A 1 709 ? 218.075 210.280 171.945 1.00 76.69  ? 709 THR A CA  1 
ATOM   5484  C  C   . THR A 1 709 ? 219.114 211.379 171.783 1.00 76.69  ? 709 THR A C   1 
ATOM   5485  O  O   . THR A 1 709 ? 218.745 212.557 171.732 1.00 76.69  ? 709 THR A O   1 
ATOM   5486  C  CB  . THR A 1 709 ? 217.583 210.286 173.396 1.00 76.69  ? 709 THR A CB  1 
ATOM   5487  O  OG1 . THR A 1 709 ? 218.686 210.045 174.277 1.00 76.69  ? 709 THR A OG1 1 
ATOM   5488  C  CG2 . THR A 1 709 ? 216.525 209.214 173.607 1.00 76.69  ? 709 THR A CG2 1 
ATOM   5489  N  N   . GLY A 1 710 ? 220.396 211.031 171.698 1.00 72.40  ? 710 GLY A N   1 
ATOM   5490  C  CA  . GLY A 1 710 ? 221.450 212.028 171.648 1.00 72.40  ? 710 GLY A CA  1 
ATOM   5491  C  C   . GLY A 1 710 ? 221.707 212.607 170.272 1.00 72.40  ? 710 GLY A C   1 
ATOM   5492  O  O   . GLY A 1 710 ? 222.847 212.602 169.797 1.00 72.40  ? 710 GLY A O   1 
ATOM   5493  N  N   . PHE A 1 711 ? 220.651 213.109 169.628 1.00 69.41  ? 711 PHE A N   1 
ATOM   5494  C  CA  . PHE A 1 711 ? 220.736 213.697 168.291 1.00 69.41  ? 711 PHE A CA  1 
ATOM   5495  C  C   . PHE A 1 711 ? 221.421 212.755 167.305 1.00 69.41  ? 711 PHE A C   1 
ATOM   5496  O  O   . PHE A 1 711 ? 222.195 213.188 166.448 1.00 69.41  ? 711 PHE A O   1 
ATOM   5497  C  CB  . PHE A 1 711 ? 221.444 215.048 168.326 1.00 69.41  ? 711 PHE A CB  1 
ATOM   5498  C  CG  . PHE A 1 711 ? 221.146 215.922 167.141 1.00 69.41  ? 711 PHE A CG  1 
ATOM   5499  C  CD1 . PHE A 1 711 ? 219.846 216.142 166.729 1.00 69.41  ? 711 PHE A CD1 1 
ATOM   5500  C  CD2 . PHE A 1 711 ? 222.171 216.532 166.443 1.00 69.41  ? 711 PHE A CD2 1 
ATOM   5501  C  CE1 . PHE A 1 711 ? 219.576 216.956 165.643 1.00 69.41  ? 711 PHE A CE1 1 
ATOM   5502  C  CE2 . PHE A 1 711 ? 221.904 217.341 165.356 1.00 69.41  ? 711 PHE A CE2 1 
ATOM   5503  C  CZ  . PHE A 1 711 ? 220.604 217.553 164.960 1.00 69.41  ? 711 PHE A CZ  1 
ATOM   5504  N  N   . SER A 1 712 ? 221.148 211.454 167.438 1.00 66.04  ? 712 SER A N   1 
ATOM   5505  C  CA  . SER A 1 712 ? 221.638 210.432 166.518 1.00 66.04  ? 712 SER A CA  1 
ATOM   5506  C  C   . SER A 1 712 ? 223.160 210.355 166.481 1.00 66.04  ? 712 SER A C   1 
ATOM   5507  O  O   . SER A 1 712 ? 223.731 209.810 165.538 1.00 66.04  ? 712 SER A O   1 
ATOM   5508  C  CB  . SER A 1 712 ? 221.092 210.658 165.106 1.00 66.04  ? 712 SER A CB  1 
ATOM   5509  O  OG  . SER A 1 712 ? 221.531 209.647 164.223 1.00 66.04  ? 712 SER A OG  1 
ATOM   5510  N  N   . GLY A 1 713 ? 223.835 210.884 167.495 1.00 66.73  ? 713 GLY A N   1 
ATOM   5511  C  CA  . GLY A 1 713 ? 225.281 210.954 167.443 1.00 66.73  ? 713 GLY A CA  1 
ATOM   5512  C  C   . GLY A 1 713 ? 225.966 209.627 167.682 1.00 66.73  ? 713 GLY A C   1 
ATOM   5513  O  O   . GLY A 1 713 ? 226.595 209.066 166.779 1.00 66.73  ? 713 GLY A O   1 
ATOM   5514  N  N   . LEU A 1 714 ? 225.836 209.111 168.905 1.00 68.17  ? 714 LEU A N   1 
ATOM   5515  C  CA  . LEU A 1 714 ? 226.453 207.834 169.244 1.00 68.17  ? 714 LEU A CA  1 
ATOM   5516  C  C   . LEU A 1 714 ? 225.814 206.687 168.479 1.00 68.17  ? 714 LEU A C   1 
ATOM   5517  O  O   . LEU A 1 714 ? 226.402 205.608 168.372 1.00 68.17  ? 714 LEU A O   1 
ATOM   5518  C  CB  . LEU A 1 714 ? 226.377 207.606 170.753 1.00 68.17  ? 714 LEU A CB  1 
ATOM   5519  C  CG  . LEU A 1 714 ? 225.057 207.254 171.438 1.00 68.17  ? 714 LEU A CG  1 
ATOM   5520  C  CD1 . LEU A 1 714 ? 225.358 206.705 172.815 1.00 68.17  ? 714 LEU A CD1 1 
ATOM   5521  C  CD2 . LEU A 1 714 ? 224.139 208.459 171.544 1.00 68.17  ? 714 LEU A CD2 1 
ATOM   5522  N  N   . SER A 1 715 ? 224.617 206.902 167.937 1.00 66.79  ? 715 SER A N   1 
ATOM   5523  C  CA  . SER A 1 715 ? 224.029 205.937 167.020 1.00 66.79  ? 715 SER A CA  1 
ATOM   5524  C  C   . SER A 1 715 ? 224.729 205.940 165.675 1.00 66.79  ? 715 SER A C   1 
ATOM   5525  O  O   . SER A 1 715 ? 224.409 205.112 164.818 1.00 66.79  ? 715 SER A O   1 
ATOM   5526  C  CB  . SER A 1 715 ? 222.541 206.224 166.823 1.00 66.79  ? 715 SER A CB  1 
ATOM   5527  O  OG  . SER A 1 715 ? 221.986 205.360 165.846 1.00 66.79  ? 715 SER A OG  1 
ATOM   5528  N  N   . ARG A 1 716 ? 225.654 206.868 165.461 1.00 71.57  ? 716 ARG A N   1 
ATOM   5529  C  CA  . ARG A 1 716 ? 226.337 207.035 164.189 1.00 71.57  ? 716 ARG A CA  1 
ATOM   5530  C  C   . ARG A 1 716 ? 227.836 206.820 164.298 1.00 71.57  ? 716 ARG A C   1 
ATOM   5531  O  O   . ARG A 1 716 ? 228.441 206.207 163.415 1.00 71.57  ? 716 ARG A O   1 
ATOM   5532  C  CB  . ARG A 1 716 ? 226.053 208.442 163.643 1.00 71.57  ? 716 ARG A CB  1 
ATOM   5533  C  CG  . ARG A 1 716 ? 226.597 208.731 162.253 1.00 71.57  ? 716 ARG A CG  1 
ATOM   5534  C  CD  . ARG A 1 716 ? 226.443 207.548 161.326 1.00 71.57  ? 716 ARG A CD  1 
ATOM   5535  N  NE  . ARG A 1 716 ? 225.052 207.130 161.205 1.00 71.57  ? 716 ARG A NE  1 
ATOM   5536  C  CZ  . ARG A 1 716 ? 224.651 206.085 160.498 1.00 71.57  ? 716 ARG A CZ  1 
ATOM   5537  N  NH1 . ARG A 1 716 ? 225.512 205.332 159.834 1.00 71.57  ? 716 ARG A NH1 1 
ATOM   5538  N  NH2 . ARG A 1 716 ? 223.356 205.787 160.457 1.00 71.57  ? 716 ARG A NH2 1 
ATOM   5539  N  N   . LEU A 1 717 ? 228.452 207.307 165.371 1.00 71.98  ? 717 LEU A N   1 
ATOM   5540  C  CA  . LEU A 1 717 ? 229.898 207.464 165.419 1.00 71.98  ? 717 LEU A CA  1 
ATOM   5541  C  C   . LEU A 1 717 ? 230.595 206.533 166.399 1.00 71.98  ? 717 LEU A C   1 
ATOM   5542  O  O   . LEU A 1 717 ? 231.575 205.883 166.026 1.00 71.98  ? 717 LEU A O   1 
ATOM   5543  C  CB  . LEU A 1 717 ? 230.231 208.938 165.723 1.00 71.98  ? 717 LEU A CB  1 
ATOM   5544  C  CG  . LEU A 1 717 ? 229.732 209.639 166.996 1.00 71.98  ? 717 LEU A CG  1 
ATOM   5545  C  CD1 . LEU A 1 717 ? 230.646 209.443 168.200 1.00 71.98  ? 717 LEU A CD1 1 
ATOM   5546  C  CD2 . LEU A 1 717 ? 229.486 211.119 166.734 1.00 71.98  ? 717 LEU A CD2 1 
ATOM   5547  N  N   . VAL A 1 718 ? 230.124 206.439 167.642 1.00 77.85  ? 718 VAL A N   1 
ATOM   5548  C  CA  . VAL A 1 718 ? 230.917 205.763 168.665 1.00 77.85  ? 718 VAL A CA  1 
ATOM   5549  C  C   . VAL A 1 718 ? 230.946 204.257 168.425 1.00 77.85  ? 718 VAL A C   1 
ATOM   5550  O  O   . VAL A 1 718 ? 231.984 203.609 168.606 1.00 77.85  ? 718 VAL A O   1 
ATOM   5551  C  CB  . VAL A 1 718 ? 230.405 206.116 170.077 1.00 77.85  ? 718 VAL A CB  1 
ATOM   5552  C  CG1 . VAL A 1 718 ? 229.078 205.434 170.381 1.00 77.85  ? 718 VAL A CG1 1 
ATOM   5553  C  CG2 . VAL A 1 718 ? 231.448 205.764 171.128 1.00 77.85  ? 718 VAL A CG2 1 
ATOM   5554  N  N   . SER A 1 719 ? 229.825 203.678 167.997 1.00 70.33  ? 719 SER A N   1 
ATOM   5555  C  CA  . SER A 1 719 ? 229.698 202.234 167.942 1.00 70.33  ? 719 SER A CA  1 
ATOM   5556  C  C   . SER A 1 719 ? 229.126 201.712 166.635 1.00 70.33  ? 719 SER A C   1 
ATOM   5557  O  O   . SER A 1 719 ? 229.070 200.492 166.454 1.00 70.33  ? 719 SER A O   1 
ATOM   5558  C  CB  . SER A 1 719 ? 228.831 201.740 169.107 1.00 70.33  ? 719 SER A CB  1 
ATOM   5559  O  OG  . SER A 1 719 ? 227.584 202.409 169.131 1.00 70.33  ? 719 SER A OG  1 
ATOM   5560  N  N   . LEU A 1 720 ? 228.708 202.586 165.729 1.00 65.26  ? 720 LEU A N   1 
ATOM   5561  C  CA  . LEU A 1 720 ? 228.127 202.214 164.444 1.00 65.26  ? 720 LEU A CA  1 
ATOM   5562  C  C   . LEU A 1 720 ? 226.960 201.240 164.594 1.00 65.26  ? 720 LEU A C   1 
ATOM   5563  O  O   . LEU A 1 720 ? 226.917 200.220 163.895 1.00 65.26  ? 720 LEU A O   1 
ATOM   5564  C  CB  . LEU A 1 720 ? 229.197 201.594 163.543 1.00 65.26  ? 720 LEU A CB  1 
ATOM   5565  C  CG  . LEU A 1 720 ? 230.413 202.439 163.171 1.00 65.26  ? 720 LEU A CG  1 
ATOM   5566  C  CD1 . LEU A 1 720 ? 231.479 202.361 164.251 1.00 65.26  ? 720 LEU A CD1 1 
ATOM   5567  C  CD2 . LEU A 1 720 ? 230.970 201.988 161.833 1.00 65.26  ? 720 LEU A CD2 1 
ATOM   5568  N  N   . PRO A 1 721 ? 225.979 201.514 165.459 1.00 65.58  ? 721 PRO A N   1 
ATOM   5569  C  CA  . PRO A 1 721 ? 224.910 200.534 165.670 1.00 65.58  ? 721 PRO A CA  1 
ATOM   5570  C  C   . PRO A 1 721 ? 223.904 200.479 164.546 1.00 65.58  ? 721 PRO A C   1 
ATOM   5571  O  O   . PRO A 1 721 ? 222.847 199.860 164.722 1.00 65.58  ? 721 PRO A O   1 
ATOM   5572  C  CB  . PRO A 1 721 ? 224.254 201.010 166.967 1.00 65.58  ? 721 PRO A CB  1 
ATOM   5573  C  CG  . PRO A 1 721 ? 224.419 202.461 166.923 1.00 65.58  ? 721 PRO A CG  1 
ATOM   5574  C  CD  . PRO A 1 721 ? 225.757 202.721 166.274 1.00 65.58  ? 721 PRO A CD  1 
ATOM   5575  N  N   . VAL A 1 722 ? 224.182 201.105 163.407 1.00 69.59  ? 722 VAL A N   1 
ATOM   5576  C  CA  . VAL A 1 722 ? 223.264 201.053 162.278 1.00 69.59  ? 722 VAL A CA  1 
ATOM   5577  C  C   . VAL A 1 722 ? 223.807 200.002 161.314 1.00 69.59  ? 722 VAL A C   1 
ATOM   5578  O  O   . VAL A 1 722 ? 223.504 200.015 160.116 1.00 69.59  ? 722 VAL A O   1 
ATOM   5579  C  CB  . VAL A 1 722 ? 223.094 202.444 161.631 1.00 69.59  ? 722 VAL A CB  1 
ATOM   5580  C  CG1 . VAL A 1 722 ? 222.016 202.444 160.541 1.00 69.59  ? 722 VAL A CG1 1 
ATOM   5581  C  CG2 . VAL A 1 722 ? 222.750 203.467 162.694 1.00 69.59  ? 722 VAL A CG2 1 
ATOM   5582  N  N   . THR A 1 723 ? 224.629 199.081 161.829 1.00 62.83  ? 723 THR A N   1 
ATOM   5583  C  CA  . THR A 1 723 ? 224.959 197.896 161.050 1.00 62.83  ? 723 THR A CA  1 
ATOM   5584  C  C   . THR A 1 723 ? 223.665 197.239 160.609 1.00 62.83  ? 723 THR A C   1 
ATOM   5585  O  O   . THR A 1 723 ? 223.414 197.045 159.414 1.00 62.83  ? 723 THR A O   1 
ATOM   5586  C  CB  . THR A 1 723 ? 225.803 196.929 161.873 1.00 62.83  ? 723 THR A CB  1 
ATOM   5587  O  OG1 . THR A 1 723 ? 225.093 196.589 163.068 1.00 62.83  ? 723 THR A OG1 1 
ATOM   5588  C  CG2 . THR A 1 723 ? 227.116 197.563 162.246 1.00 62.83  ? 723 THR A CG2 1 
ATOM   5589  N  N   . GLU A 1 724 ? 222.801 196.967 161.577 1.00 56.88  ? 724 GLU A N   1 
ATOM   5590  C  CA  . GLU A 1 724 ? 221.398 196.731 161.303 1.00 56.88  ? 724 GLU A CA  1 
ATOM   5591  C  C   . GLU A 1 724 ? 220.602 197.403 162.403 1.00 56.88  ? 724 GLU A C   1 
ATOM   5592  O  O   . GLU A 1 724 ? 220.998 197.378 163.568 1.00 56.88  ? 724 GLU A O   1 
ATOM   5593  C  CB  . GLU A 1 724 ? 221.048 195.237 161.218 1.00 56.88  ? 724 GLU A CB  1 
ATOM   5594  C  CG  . GLU A 1 724 ? 220.899 194.502 162.542 1.00 56.88  ? 724 GLU A CG  1 
ATOM   5595  C  CD  . GLU A 1 724 ? 222.179 193.854 163.004 1.00 56.88  ? 724 GLU A CD  1 
ATOM   5596  O  OE1 . GLU A 1 724 ? 223.261 194.252 162.524 1.00 56.88  ? 724 GLU A OE1 1 
ATOM   5597  O  OE2 . GLU A 1 724 ? 222.099 192.927 163.834 1.00 56.88  ? 724 GLU A OE2 1 
ATOM   5598  N  N   . ILE A 1 725 ? 219.507 198.037 162.021 1.00 53.32  ? 725 ILE A N   1 
ATOM   5599  C  CA  . ILE A 1 725 ? 218.558 198.531 163.005 1.00 53.32  ? 725 ILE A CA  1 
ATOM   5600  C  C   . ILE A 1 725 ? 217.224 197.851 162.752 1.00 53.32  ? 725 ILE A C   1 
ATOM   5601  O  O   . ILE A 1 725 ? 216.873 197.514 161.617 1.00 53.32  ? 725 ILE A O   1 
ATOM   5602  C  CB  . ILE A 1 725 ? 218.408 200.065 163.003 1.00 53.32  ? 725 ILE A CB  1 
ATOM   5603  C  CG1 . ILE A 1 725 ? 217.827 200.573 161.693 1.00 53.32  ? 725 ILE A CG1 1 
ATOM   5604  C  CG2 . ILE A 1 725 ? 219.750 200.730 163.239 1.00 53.32  ? 725 ILE A CG2 1 
ATOM   5605  C  CD1 . ILE A 1 725 ? 217.472 202.034 161.772 1.00 53.32  ? 725 ILE A CD1 1 
ATOM   5606  N  N   . LYS A 1 726 ? 216.495 197.624 163.830 1.00 48.99  ? 726 LYS A N   1 
ATOM   5607  C  CA  . LYS A 1 726 ? 215.350 196.733 163.841 1.00 48.99  ? 726 LYS A CA  1 
ATOM   5608  C  C   . LYS A 1 726 ? 214.064 197.540 163.916 1.00 48.99  ? 726 LYS A C   1 
ATOM   5609  O  O   . LYS A 1 726 ? 214.071 198.751 164.140 1.00 48.99  ? 726 LYS A O   1 
ATOM   5610  C  CB  . LYS A 1 726 ? 215.456 195.757 165.017 1.00 48.99  ? 726 LYS A CB  1 
ATOM   5611  C  CG  . LYS A 1 726 ? 214.890 194.375 164.755 1.00 48.99  ? 726 LYS A CG  1 
ATOM   5612  C  CD  . LYS A 1 726 ? 215.419 193.365 165.762 1.00 48.99  ? 726 LYS A CD  1 
ATOM   5613  C  CE  . LYS A 1 726 ? 216.729 192.760 165.301 1.00 48.99  ? 726 LYS A CE  1 
ATOM   5614  N  NZ  . LYS A 1 726 ? 217.137 191.638 166.177 1.00 48.99  ? 726 LYS A NZ  1 
ATOM   5615  N  N   . ILE A 1 727 ? 212.952 196.852 163.703 1.00 56.37  ? 727 ILE A N   1 
ATOM   5616  C  CA  . ILE A 1 727 ? 211.628 197.403 163.941 1.00 56.37  ? 727 ILE A CA  1 
ATOM   5617  C  C   . ILE A 1 727 ? 210.944 196.528 164.975 1.00 56.37  ? 727 ILE A C   1 
ATOM   5618  O  O   . ILE A 1 727 ? 210.862 195.307 164.803 1.00 56.37  ? 727 ILE A O   1 
ATOM   5619  C  CB  . ILE A 1 727 ? 210.791 197.477 162.656 1.00 56.37  ? 727 ILE A CB  1 
ATOM   5620  C  CG1 . ILE A 1 727 ? 211.395 198.500 161.703 1.00 56.37  ? 727 ILE A CG1 1 
ATOM   5621  C  CG2 . ILE A 1 727 ? 209.365 197.848 162.987 1.00 56.37  ? 727 ILE A CG2 1 
ATOM   5622  C  CD1 . ILE A 1 727 ? 210.514 198.820 160.529 1.00 56.37  ? 727 ILE A CD1 1 
ATOM   5623  N  N   . ASP A 1 728 ? 210.465 197.145 166.049 1.00 74.83  ? 728 ASP A N   1 
ATOM   5624  C  CA  . ASP A 1 728 ? 209.839 196.381 167.114 1.00 74.83  ? 728 ASP A CA  1 
ATOM   5625  C  C   . ASP A 1 728 ? 208.553 195.738 166.615 1.00 74.83  ? 728 ASP A C   1 
ATOM   5626  O  O   . ASP A 1 728 ? 207.948 196.181 165.636 1.00 74.83  ? 728 ASP A O   1 
ATOM   5627  C  CB  . ASP A 1 728 ? 209.553 197.278 168.318 1.00 74.83  ? 728 ASP A CB  1 
ATOM   5628  C  CG  . ASP A 1 728 ? 208.650 198.445 167.976 1.00 74.83  ? 728 ASP A CG  1 
ATOM   5629  O  OD1 . ASP A 1 728 ? 207.419 198.250 167.907 1.00 74.83  ? 728 ASP A OD1 1 
ATOM   5630  O  OD2 . ASP A 1 728 ? 209.174 199.562 167.779 1.00 74.83  ? 728 ASP A OD2 1 
ATOM   5631  N  N   . LYS A 1 729 ? 208.149 194.665 167.295 1.00 76.27  ? 729 LYS A N   1 
ATOM   5632  C  CA  . LYS A 1 729 ? 206.940 193.947 166.910 1.00 76.27  ? 729 LYS A CA  1 
ATOM   5633  C  C   . LYS A 1 729 ? 205.721 194.856 166.952 1.00 76.27  ? 729 LYS A C   1 
ATOM   5634  O  O   . LYS A 1 729 ? 204.818 194.742 166.114 1.00 76.27  ? 729 LYS A O   1 
ATOM   5635  C  CB  . LYS A 1 729 ? 206.742 192.744 167.835 1.00 76.27  ? 729 LYS A CB  1 
ATOM   5636  C  CG  . LYS A 1 729 ? 205.401 192.046 167.695 1.00 76.27  ? 729 LYS A CG  1 
ATOM   5637  C  CD  . LYS A 1 729 ? 205.355 191.185 166.448 1.00 76.27  ? 729 LYS A CD  1 
ATOM   5638  C  CE  . LYS A 1 729 ? 203.952 191.125 165.873 1.00 76.27  ? 729 LYS A CE  1 
ATOM   5639  N  NZ  . LYS A 1 729 ? 203.724 192.235 164.913 1.00 76.27  ? 729 LYS A NZ  1 
ATOM   5640  N  N   . SER A 1 730 ? 205.691 195.785 167.908 1.00 79.57  ? 730 SER A N   1 
ATOM   5641  C  CA  . SER A 1 730 ? 204.485 196.557 168.173 1.00 79.57  ? 730 SER A CA  1 
ATOM   5642  C  C   . SER A 1 730 ? 204.140 197.526 167.051 1.00 79.57  ? 730 SER A C   1 
ATOM   5643  O  O   . SER A 1 730 ? 203.017 198.041 167.021 1.00 79.57  ? 730 SER A O   1 
ATOM   5644  C  CB  . SER A 1 730 ? 204.638 197.319 169.489 1.00 79.57  ? 730 SER A CB  1 
ATOM   5645  O  OG  . SER A 1 730 ? 205.673 198.281 169.403 1.00 79.57  ? 730 SER A OG  1 
ATOM   5646  N  N   . PHE A 1 731 ? 205.065 197.796 166.134 1.00 81.53  ? 731 PHE A N   1 
ATOM   5647  C  CA  . PHE A 1 731 ? 204.765 198.724 165.051 1.00 81.53  ? 731 PHE A CA  1 
ATOM   5648  C  C   . PHE A 1 731 ? 204.258 198.018 163.799 1.00 81.53  ? 731 PHE A C   1 
ATOM   5649  O  O   . PHE A 1 731 ? 203.357 198.526 163.126 1.00 81.53  ? 731 PHE A O   1 
ATOM   5650  C  CB  . PHE A 1 731 ? 205.997 199.565 164.709 1.00 81.53  ? 731 PHE A CB  1 
ATOM   5651  C  CG  . PHE A 1 731 ? 206.260 200.676 165.677 1.00 81.53  ? 731 PHE A CG  1 
ATOM   5652  C  CD1 . PHE A 1 731 ? 205.278 201.095 166.555 1.00 81.53  ? 731 PHE A CD1 1 
ATOM   5653  C  CD2 . PHE A 1 731 ? 207.489 201.306 165.706 1.00 81.53  ? 731 PHE A CD2 1 
ATOM   5654  C  CE1 . PHE A 1 731 ? 205.519 202.119 167.446 1.00 81.53  ? 731 PHE A CE1 1 
ATOM   5655  C  CE2 . PHE A 1 731 ? 207.737 202.330 166.596 1.00 81.53  ? 731 PHE A CE2 1 
ATOM   5656  C  CZ  . PHE A 1 731 ? 206.750 202.738 167.466 1.00 81.53  ? 731 PHE A CZ  1 
ATOM   5657  N  N   . VAL A 1 732 ? 204.831 196.862 163.465 1.00 82.82  ? 732 VAL A N   1 
ATOM   5658  C  CA  . VAL A 1 732 ? 204.496 196.213 162.198 1.00 82.82  ? 732 VAL A CA  1 
ATOM   5659  C  C   . VAL A 1 732 ? 203.039 195.774 162.193 1.00 82.82  ? 732 VAL A C   1 
ATOM   5660  O  O   . VAL A 1 732 ? 202.323 195.946 161.200 1.00 82.82  ? 732 VAL A O   1 
ATOM   5661  C  CB  . VAL A 1 732 ? 205.448 195.036 161.927 1.00 82.82  ? 732 VAL A CB  1 
ATOM   5662  C  CG1 . VAL A 1 732 ? 204.880 194.128 160.850 1.00 82.82  ? 732 VAL A CG1 1 
ATOM   5663  C  CG2 . VAL A 1 732 ? 206.811 195.563 161.507 1.00 82.82  ? 732 VAL A CG2 1 
ATOM   5664  N  N   . ASP A 1 733 ? 202.578 195.205 163.308 1.00 88.52  ? 733 ASP A N   1 
ATOM   5665  C  CA  . ASP A 1 733 ? 201.195 194.741 163.378 1.00 88.52  ? 733 ASP A CA  1 
ATOM   5666  C  C   . ASP A 1 733 ? 200.214 195.902 163.287 1.00 88.52  ? 733 ASP A C   1 
ATOM   5667  O  O   . ASP A 1 733 ? 199.109 195.754 162.752 1.00 88.52  ? 733 ASP A O   1 
ATOM   5668  C  CB  . ASP A 1 733 ? 200.974 193.940 164.661 1.00 88.52  ? 733 ASP A CB  1 
ATOM   5669  C  CG  . ASP A 1 733 ? 201.272 194.743 165.911 1.00 88.52  ? 733 ASP A CG  1 
ATOM   5670  O  OD1 . ASP A 1 733 ? 201.720 195.901 165.785 1.00 88.52  ? 733 ASP A OD1 1 
ATOM   5671  O  OD2 . ASP A 1 733 ? 201.061 194.213 167.022 1.00 88.52  ? 733 ASP A OD2 1 
ATOM   5672  N  N   . ARG A 1 734 ? 200.598 197.063 163.804 1.00 89.68  ? 734 ARG A N   1 
ATOM   5673  C  CA  . ARG A 1 734 ? 199.756 198.249 163.763 1.00 89.68  ? 734 ARG A CA  1 
ATOM   5674  C  C   . ARG A 1 734 ? 200.089 199.156 162.585 1.00 89.68  ? 734 ARG A C   1 
ATOM   5675  O  O   . ARG A 1 734 ? 199.617 200.297 162.548 1.00 89.68  ? 734 ARG A O   1 
ATOM   5676  C  CB  . ARG A 1 734 ? 199.894 199.013 165.082 1.00 89.68  ? 734 ARG A CB  1 
ATOM   5677  C  CG  . ARG A 1 734 ? 198.710 199.886 165.456 1.00 89.68  ? 734 ARG A CG  1 
ATOM   5678  C  CD  . ARG A 1 734 ? 198.544 199.937 166.966 1.00 89.68  ? 734 ARG A CD  1 
ATOM   5679  N  NE  . ARG A 1 734 ? 199.825 200.031 167.658 1.00 89.68  ? 734 ARG A NE  1 
ATOM   5680  C  CZ  . ARG A 1 734 ? 200.555 201.135 167.746 1.00 89.68  ? 734 ARG A CZ  1 
ATOM   5681  N  NH1 . ARG A 1 734 ? 200.154 202.275 167.206 1.00 89.68  ? 734 ARG A NH1 1 
ATOM   5682  N  NH2 . ARG A 1 734 ? 201.715 201.095 168.395 1.00 89.68  ? 734 ARG A NH2 1 
ATOM   5683  N  N   . CYS A 1 735 ? 200.890 198.675 161.630 1.00 93.64  ? 735 CYS A N   1 
ATOM   5684  C  CA  . CYS A 1 735 ? 201.376 199.518 160.542 1.00 93.64  ? 735 CYS A CA  1 
ATOM   5685  C  C   . CYS A 1 735 ? 200.255 200.111 159.699 1.00 93.64  ? 735 CYS A C   1 
ATOM   5686  O  O   . CYS A 1 735 ? 200.471 201.134 159.040 1.00 93.64  ? 735 CYS A O   1 
ATOM   5687  C  CB  . CYS A 1 735 ? 202.324 198.719 159.645 1.00 93.64  ? 735 CYS A CB  1 
ATOM   5688  S  SG  . CYS A 1 735 ? 203.321 199.728 158.523 1.00 93.64  ? 735 CYS A SG  1 
ATOM   5689  N  N   . LEU A 1 736 ? 199.064 199.511 159.714 1.00 95.50  ? 736 LEU A N   1 
ATOM   5690  C  CA  . LEU A 1 736 ? 197.962 200.025 158.908 1.00 95.50  ? 736 LEU A CA  1 
ATOM   5691  C  C   . LEU A 1 736 ? 197.471 201.387 159.381 1.00 95.50  ? 736 LEU A C   1 
ATOM   5692  O  O   . LEU A 1 736 ? 196.682 202.020 158.671 1.00 95.50  ? 736 LEU A O   1 
ATOM   5693  C  CB  . LEU A 1 736 ? 196.806 199.026 158.907 1.00 95.50  ? 736 LEU A CB  1 
ATOM   5694  C  CG  . LEU A 1 736 ? 197.055 197.760 158.089 1.00 95.50  ? 736 LEU A CG  1 
ATOM   5695  C  CD1 . LEU A 1 736 ? 195.944 196.744 158.309 1.00 95.50  ? 736 LEU A CD1 1 
ATOM   5696  C  CD2 . LEU A 1 736 ? 197.197 198.099 156.614 1.00 95.50  ? 736 LEU A CD2 1 
ATOM   5697  N  N   . THR A 1 737 ? 197.901 201.846 160.557 1.00 94.67  ? 737 THR A N   1 
ATOM   5698  C  CA  . THR A 1 737 ? 197.569 203.182 161.037 1.00 94.67  ? 737 THR A CA  1 
ATOM   5699  C  C   . THR A 1 737 ? 198.713 204.167 160.813 1.00 94.67  ? 737 THR A C   1 
ATOM   5700  O  O   . THR A 1 737 ? 198.497 205.266 160.290 1.00 94.67  ? 737 THR A O   1 
ATOM   5701  C  CB  . THR A 1 737 ? 197.198 203.133 162.523 1.00 94.67  ? 737 THR A CB  1 
ATOM   5702  O  OG1 . THR A 1 737 ? 198.181 202.374 163.238 1.00 94.67  ? 737 THR A OG1 1 
ATOM   5703  C  CG2 . THR A 1 737 ? 195.833 202.488 162.709 1.00 94.67  ? 737 THR A CG2 1 
ATOM   5704  N  N   . GLU A 1 738 ? 199.931 203.793 161.203 1.00 90.93  ? 738 GLU A N   1 
ATOM   5705  C  CA  . GLU A 1 738 ? 201.107 204.638 160.990 1.00 90.93  ? 738 GLU A CA  1 
ATOM   5706  C  C   . GLU A 1 738 ? 201.729 204.351 159.622 1.00 90.93  ? 738 GLU A C   1 
ATOM   5707  O  O   . GLU A 1 738 ? 202.806 203.774 159.495 1.00 90.93  ? 738 GLU A O   1 
ATOM   5708  C  CB  . GLU A 1 738 ? 202.117 204.442 162.114 1.00 90.93  ? 738 GLU A CB  1 
ATOM   5709  C  CG  . GLU A 1 738 ? 202.377 202.994 162.483 1.00 90.93  ? 738 GLU A CG  1 
ATOM   5710  C  CD  . GLU A 1 738 ? 201.617 202.567 163.722 1.00 90.93  ? 738 GLU A CD  1 
ATOM   5711  O  OE1 . GLU A 1 738 ? 200.404 202.851 163.804 1.00 90.93  ? 738 GLU A OE1 1 
ATOM   5712  O  OE2 . GLU A 1 738 ? 202.233 201.948 164.616 1.00 90.93  ? 738 GLU A OE2 1 
ATOM   5713  N  N   . LYS A 1 739 ? 201.015 204.775 158.578 1.00 87.97  ? 739 LYS A N   1 
ATOM   5714  C  CA  . LYS A 1 739 ? 201.560 204.676 157.231 1.00 87.97  ? 739 LYS A CA  1 
ATOM   5715  C  C   . LYS A 1 739 ? 202.811 205.523 157.070 1.00 87.97  ? 739 LYS A C   1 
ATOM   5716  O  O   . LYS A 1 739 ? 203.584 205.304 156.131 1.00 87.97  ? 739 LYS A O   1 
ATOM   5717  C  CB  . LYS A 1 739 ? 200.510 205.098 156.204 1.00 87.97  ? 739 LYS A CB  1 
ATOM   5718  C  CG  . LYS A 1 739 ? 199.696 203.949 155.637 1.00 87.97  ? 739 LYS A CG  1 
ATOM   5719  C  CD  . LYS A 1 739 ? 198.577 203.548 156.581 1.00 87.97  ? 739 LYS A CD  1 
ATOM   5720  C  CE  . LYS A 1 739 ? 197.451 204.568 156.567 1.00 87.97  ? 739 LYS A CE  1 
ATOM   5721  N  NZ  . LYS A 1 739 ? 196.275 204.108 157.355 1.00 87.97  ? 739 LYS A NZ  1 
ATOM   5722  N  N   . ARG A 1 740 ? 203.033 206.471 157.979 1.00 87.09  ? 740 ARG A N   1 
ATOM   5723  C  CA  . ARG A 1 740 ? 204.177 207.367 157.888 1.00 87.09  ? 740 ARG A CA  1 
ATOM   5724  C  C   . ARG A 1 740 ? 205.493 206.643 158.122 1.00 87.09  ? 740 ARG A C   1 
ATOM   5725  O  O   . ARG A 1 740 ? 206.555 207.212 157.853 1.00 87.09  ? 740 ARG A O   1 
ATOM   5726  C  CB  . ARG A 1 740 ? 204.010 208.508 158.893 1.00 87.09  ? 740 ARG A CB  1 
ATOM   5727  C  CG  . ARG A 1 740 ? 203.106 209.649 158.422 1.00 87.09  ? 740 ARG A CG  1 
ATOM   5728  C  CD  . ARG A 1 740 ? 201.641 209.224 158.287 1.00 87.09  ? 740 ARG A CD  1 
ATOM   5729  N  NE  . ARG A 1 740 ? 201.070 208.735 159.537 1.00 87.09  ? 740 ARG A NE  1 
ATOM   5730  C  CZ  . ARG A 1 740 ? 200.078 207.856 159.616 1.00 87.09  ? 740 ARG A CZ  1 
ATOM   5731  N  NH1 . ARG A 1 740 ? 199.541 207.321 158.532 1.00 87.09  ? 740 ARG A NH1 1 
ATOM   5732  N  NH2 . ARG A 1 740 ? 199.614 207.507 160.812 1.00 87.09  ? 740 ARG A NH2 1 
ATOM   5733  N  N   . ILE A 1 741 ? 205.449 205.401 158.607 1.00 82.90  ? 741 ILE A N   1 
ATOM   5734  C  CA  . ILE A 1 741 ? 206.645 204.593 158.795 1.00 82.90  ? 741 ILE A CA  1 
ATOM   5735  C  C   . ILE A 1 741 ? 207.427 204.414 157.498 1.00 82.90  ? 741 ILE A C   1 
ATOM   5736  O  O   . ILE A 1 741 ? 208.607 204.035 157.530 1.00 82.90  ? 741 ILE A O   1 
ATOM   5737  C  CB  . ILE A 1 741 ? 206.238 203.239 159.425 1.00 82.90  ? 741 ILE A CB  1 
ATOM   5738  C  CG1 . ILE A 1 741 ? 205.652 203.471 160.817 1.00 82.90  ? 741 ILE A CG1 1 
ATOM   5739  C  CG2 . ILE A 1 741 ? 207.416 202.280 159.546 1.00 82.90  ? 741 ILE A CG2 1 
ATOM   5740  C  CD1 . ILE A 1 741 ? 206.682 203.880 161.850 1.00 82.90  ? 741 ILE A CD1 1 
ATOM   5741  N  N   . LEU A 1 742 ? 206.804 204.696 156.351 1.00 81.36  ? 742 LEU A N   1 
ATOM   5742  C  CA  . LEU A 1 742 ? 207.566 204.761 155.111 1.00 81.36  ? 742 LEU A CA  1 
ATOM   5743  C  C   . LEU A 1 742 ? 208.693 205.776 155.220 1.00 81.36  ? 742 LEU A C   1 
ATOM   5744  O  O   . LEU A 1 742 ? 209.784 205.554 154.689 1.00 81.36  ? 742 LEU A O   1 
ATOM   5745  C  CB  . LEU A 1 742 ? 206.645 205.101 153.935 1.00 81.36  ? 742 LEU A CB  1 
ATOM   5746  C  CG  . LEU A 1 742 ? 205.904 206.441 153.899 1.00 81.36  ? 742 LEU A CG  1 
ATOM   5747  C  CD1 . LEU A 1 742 ? 206.703 207.496 153.145 1.00 81.36  ? 742 LEU A CD1 1 
ATOM   5748  C  CD2 . LEU A 1 742 ? 204.534 206.268 153.261 1.00 81.36  ? 742 LEU A CD2 1 
ATOM   5749  N  N   . ALA A 1 743 ? 208.451 206.886 155.917 1.00 77.56  ? 743 ALA A N   1 
ATOM   5750  C  CA  . ALA A 1 743 ? 209.501 207.875 156.123 1.00 77.56  ? 743 ALA A CA  1 
ATOM   5751  C  C   . ALA A 1 743 ? 210.633 207.306 156.967 1.00 77.56  ? 743 ALA A C   1 
ATOM   5752  O  O   . ALA A 1 743 ? 211.810 207.548 156.685 1.00 77.56  ? 743 ALA A O   1 
ATOM   5753  C  CB  . ALA A 1 743 ? 208.922 209.131 156.773 1.00 77.56  ? 743 ALA A CB  1 
ATOM   5754  N  N   . LEU A 1 744 ? 210.298 206.551 158.015 1.00 74.70  ? 744 LEU A N   1 
ATOM   5755  C  CA  . LEU A 1 744 ? 211.338 205.931 158.827 1.00 74.70  ? 744 LEU A CA  1 
ATOM   5756  C  C   . LEU A 1 744 ? 212.180 204.982 157.993 1.00 74.70  ? 744 LEU A C   1 
ATOM   5757  O  O   . LEU A 1 744 ? 213.417 205.002 158.055 1.00 74.70  ? 744 LEU A O   1 
ATOM   5758  C  CB  . LEU A 1 744 ? 210.715 205.184 160.004 1.00 74.70  ? 744 LEU A CB  1 
ATOM   5759  C  CG  . LEU A 1 744 ? 211.629 204.154 160.679 1.00 74.70  ? 744 LEU A CG  1 
ATOM   5760  C  CD1 . LEU A 1 744 ? 212.852 204.815 161.295 1.00 74.70  ? 744 LEU A CD1 1 
ATOM   5761  C  CD2 . LEU A 1 744 ? 210.866 203.361 161.726 1.00 74.70  ? 744 LEU A CD2 1 
ATOM   5762  N  N   . LEU A 1 745 ? 211.521 204.141 157.200 1.00 76.10  ? 745 LEU A N   1 
ATOM   5763  C  CA  . LEU A 1 745 ? 212.258 203.163 156.410 1.00 76.10  ? 745 LEU A CA  1 
ATOM   5764  C  C   . LEU A 1 745 ? 213.100 203.842 155.341 1.00 76.10  ? 745 LEU A C   1 
ATOM   5765  O  O   . LEU A 1 745 ? 214.218 203.404 155.061 1.00 76.10  ? 745 LEU A O   1 
ATOM   5766  C  CB  . LEU A 1 745 ? 211.301 202.144 155.798 1.00 76.10  ? 745 LEU A CB  1 
ATOM   5767  C  CG  . LEU A 1 745 ? 211.137 200.901 156.679 1.00 76.10  ? 745 LEU A CG  1 
ATOM   5768  C  CD1 . LEU A 1 745 ? 209.928 200.080 156.279 1.00 76.10  ? 745 LEU A CD1 1 
ATOM   5769  C  CD2 . LEU A 1 745 ? 212.396 200.050 156.643 1.00 76.10  ? 745 LEU A CD2 1 
ATOM   5770  N  N   . GLU A 1 746 ? 212.597 204.928 154.752 1.00 74.74  ? 746 GLU A N   1 
ATOM   5771  C  CA  . GLU A 1 746 ? 213.404 205.694 153.810 1.00 74.74  ? 746 GLU A CA  1 
ATOM   5772  C  C   . GLU A 1 746 ? 214.595 206.342 154.504 1.00 74.74  ? 746 GLU A C   1 
ATOM   5773  O  O   . GLU A 1 746 ? 215.693 206.410 153.938 1.00 74.74  ? 746 GLU A O   1 
ATOM   5774  C  CB  . GLU A 1 746 ? 212.543 206.751 153.122 1.00 74.74  ? 746 GLU A CB  1 
ATOM   5775  C  CG  . GLU A 1 746 ? 213.263 207.522 152.030 1.00 74.74  ? 746 GLU A CG  1 
ATOM   5776  C  CD  . GLU A 1 746 ? 213.600 206.658 150.830 1.00 74.74  ? 746 GLU A CD  1 
ATOM   5777  O  OE1 . GLU A 1 746 ? 212.874 205.672 150.582 1.00 74.74  ? 746 GLU A OE1 1 
ATOM   5778  O  OE2 . GLU A 1 746 ? 214.592 206.964 150.136 1.00 74.74  ? 746 GLU A OE2 1 
ATOM   5779  N  N   . ALA A 1 747 ? 214.397 206.828 155.730 1.00 70.74  ? 747 ALA A N   1 
ATOM   5780  C  CA  . ALA A 1 747 ? 215.497 207.419 156.482 1.00 70.74  ? 747 ALA A CA  1 
ATOM   5781  C  C   . ALA A 1 747 ? 216.594 206.401 156.727 1.00 70.74  ? 747 ALA A C   1 
ATOM   5782  O  O   . ALA A 1 747 ? 217.784 206.706 156.593 1.00 70.74  ? 747 ALA A O   1 
ATOM   5783  C  CB  . ALA A 1 747 ? 214.987 207.977 157.809 1.00 70.74  ? 747 ALA A CB  1 
ATOM   5784  N  N   . ILE A 1 748 ? 216.209 205.182 157.094 1.00 74.11  ? 748 ILE A N   1 
ATOM   5785  C  CA  . ILE A 1 748 ? 217.192 204.115 157.255 1.00 74.11  ? 748 ILE A CA  1 
ATOM   5786  C  C   . ILE A 1 748 ? 217.861 203.806 155.924 1.00 74.11  ? 748 ILE A C   1 
ATOM   5787  O  O   . ILE A 1 748 ? 219.089 203.697 155.835 1.00 74.11  ? 748 ILE A O   1 
ATOM   5788  C  CB  . ILE A 1 748 ? 216.532 202.861 157.850 1.00 74.11  ? 748 ILE A CB  1 
ATOM   5789  C  CG1 . ILE A 1 748 ? 215.671 203.240 159.054 1.00 74.11  ? 748 ILE A CG1 1 
ATOM   5790  C  CG2 . ILE A 1 748 ? 217.592 201.835 158.213 1.00 74.11  ? 748 ILE A CG2 1 
ATOM   5791  C  CD1 . ILE A 1 748 ? 214.576 202.250 159.361 1.00 74.11  ? 748 ILE A CD1 1 
ATOM   5792  N  N   . THR A 1 749 ? 217.059 203.682 154.866 1.00 78.49  ? 749 THR A N   1 
ATOM   5793  C  CA  . THR A 1 749 ? 217.571 203.227 153.582 1.00 78.49  ? 749 THR A CA  1 
ATOM   5794  C  C   . THR A 1 749 ? 218.532 204.233 152.977 1.00 78.49  ? 749 THR A C   1 
ATOM   5795  O  O   . THR A 1 749 ? 219.407 203.857 152.195 1.00 78.49  ? 749 THR A O   1 
ATOM   5796  C  CB  . THR A 1 749 ? 216.408 202.956 152.626 1.00 78.49  ? 749 THR A CB  1 
ATOM   5797  O  OG1 . THR A 1 749 ? 215.425 202.150 153.287 1.00 78.49  ? 749 THR A OG1 1 
ATOM   5798  C  CG2 . THR A 1 749 ? 216.889 202.224 151.381 1.00 78.49  ? 749 THR A CG2 1 
ATOM   5799  N  N   . SER A 1 750 ? 218.397 205.509 153.331 1.00 77.77  ? 750 SER A N   1 
ATOM   5800  C  CA  . SER A 1 750 ? 219.356 206.506 152.870 1.00 77.77  ? 750 SER A CA  1 
ATOM   5801  C  C   . SER A 1 750 ? 220.765 206.154 153.327 1.00 77.77  ? 750 SER A C   1 
ATOM   5802  O  O   . SER A 1 750 ? 221.668 205.925 152.511 1.00 77.77  ? 750 SER A O   1 
ATOM   5803  C  CB  . SER A 1 750 ? 218.950 207.884 153.384 1.00 77.77  ? 750 SER A CB  1 
ATOM   5804  O  OG  . SER A 1 750 ? 218.799 207.868 154.793 1.00 77.77  ? 750 SER A OG  1 
ATOM   5805  N  N   . ILE A 1 751 ? 220.965 206.081 154.641 1.00 75.23  ? 751 ILE A N   1 
ATOM   5806  C  CA  . ILE A 1 751 ? 222.285 205.779 155.173 1.00 75.23  ? 751 ILE A CA  1 
ATOM   5807  C  C   . ILE A 1 751 ? 222.693 204.365 154.780 1.00 75.23  ? 751 ILE A C   1 
ATOM   5808  O  O   . ILE A 1 751 ? 223.887 204.059 154.651 1.00 75.23  ? 751 ILE A O   1 
ATOM   5809  C  CB  . ILE A 1 751 ? 222.274 205.965 156.697 1.00 75.23  ? 751 ILE A CB  1 
ATOM   5810  C  CG1 . ILE A 1 751 ? 221.506 207.225 157.061 1.00 75.23  ? 751 ILE A CG1 1 
ATOM   5811  C  CG2 . ILE A 1 751 ? 223.671 206.181 157.191 1.00 75.23  ? 751 ILE A CG2 1 
ATOM   5812  C  CD1 . ILE A 1 751 ? 221.199 207.334 158.530 1.00 75.23  ? 751 ILE A CD1 1 
ATOM   5813  N  N   . GLY A 1 752 ? 221.715 203.478 154.594 1.00 83.09  ? 752 GLY A N   1 
ATOM   5814  C  CA  . GLY A 1 752 ? 221.981 202.122 154.161 1.00 83.09  ? 752 GLY A CA  1 
ATOM   5815  C  C   . GLY A 1 752 ? 222.560 202.015 152.768 1.00 83.09  ? 752 GLY A C   1 
ATOM   5816  O  O   . GLY A 1 752 ? 223.530 201.291 152.555 1.00 83.09  ? 752 GLY A O   1 
ATOM   5817  N  N   . GLN A 1 753 ? 221.976 202.723 151.804 1.00 90.58  ? 753 GLN A N   1 
ATOM   5818  C  CA  . GLN A 1 753 ? 222.573 202.782 150.478 1.00 90.58  ? 753 GLN A CA  1 
ATOM   5819  C  C   . GLN A 1 753 ? 223.842 203.618 150.485 1.00 90.58  ? 753 GLN A C   1 
ATOM   5820  O  O   . GLN A 1 753 ? 224.654 203.506 149.560 1.00 90.58  ? 753 GLN A O   1 
ATOM   5821  C  CB  . GLN A 1 753 ? 221.571 203.334 149.462 1.00 90.58  ? 753 GLN A CB  1 
ATOM   5822  C  CG  . GLN A 1 753 ? 221.348 204.833 149.546 1.00 90.58  ? 753 GLN A CG  1 
ATOM   5823  C  CD  . GLN A 1 753 ? 220.207 205.300 148.665 1.00 90.58  ? 753 GLN A CD  1 
ATOM   5824  O  OE1 . GLN A 1 753 ? 219.551 204.497 148.001 1.00 90.58  ? 753 GLN A OE1 1 
ATOM   5825  N  NE2 . GLN A 1 753 ? 219.963 206.605 148.654 1.00 90.58  ? 753 GLN A NE2 1 
ATOM   5826  N  N   . SER A 1 754 ? 224.026 204.453 151.509 1.00 91.14  ? 754 SER A N   1 
ATOM   5827  C  CA  . SER A 1 754 ? 225.291 205.162 151.663 1.00 91.14  ? 754 SER A CA  1 
ATOM   5828  C  C   . SER A 1 754 ? 226.428 204.195 151.982 1.00 91.14  ? 754 SER A C   1 
ATOM   5829  O  O   . SER A 1 754 ? 227.410 204.104 151.236 1.00 91.14  ? 754 SER A O   1 
ATOM   5830  C  CB  . SER A 1 754 ? 225.163 206.229 152.752 1.00 91.14  ? 754 SER A CB  1 
ATOM   5831  O  OG  . SER A 1 754 ? 224.018 207.038 152.544 1.00 91.14  ? 754 SER A OG  1 
ATOM   5832  N  N   . LEU A 1 755 ? 226.315 203.462 153.089 1.00 91.46  ? 755 LEU A N   1 
ATOM   5833  C  CA  . LEU A 1 755 ? 227.438 202.649 153.573 1.00 91.46  ? 755 LEU A CA  1 
ATOM   5834  C  C   . LEU A 1 755 ? 226.987 201.289 154.121 1.00 91.46  ? 755 LEU A C   1 
ATOM   5835  O  O   . LEU A 1 755 ? 227.405 200.855 155.195 1.00 91.46  ? 755 LEU A O   1 
ATOM   5836  C  CB  . LEU A 1 755 ? 228.265 203.432 154.598 1.00 91.46  ? 755 LEU A CB  1 
ATOM   5837  C  CG  . LEU A 1 755 ? 227.764 203.773 156.003 1.00 91.46  ? 755 LEU A CG  1 
ATOM   5838  C  CD1 . LEU A 1 755 ? 228.936 204.169 156.884 1.00 91.46  ? 755 LEU A CD1 1 
ATOM   5839  C  CD2 . LEU A 1 755 ? 226.760 204.904 155.944 1.00 91.46  ? 755 LEU A CD2 1 
ATOM   5840  N  N   . ASN A 1 756 ? 226.146 200.583 153.360 1.00 89.12  ? 756 ASN A N   1 
ATOM   5841  C  CA  . ASN A 1 756 ? 225.816 199.172 153.593 1.00 89.12  ? 756 ASN A CA  1 
ATOM   5842  C  C   . ASN A 1 756 ? 225.262 198.946 155.006 1.00 89.12  ? 756 ASN A C   1 
ATOM   5843  O  O   . ASN A 1 756 ? 225.858 198.265 155.843 1.00 89.12  ? 756 ASN A O   1 
ATOM   5844  C  CB  . ASN A 1 756 ? 227.036 198.282 153.327 1.00 89.12  ? 756 ASN A CB  1 
ATOM   5845  C  CG  . ASN A 1 756 ? 227.489 198.334 151.881 1.00 89.12  ? 756 ASN A CG  1 
ATOM   5846  O  OD1 . ASN A 1 756 ? 226.691 198.156 150.962 1.00 89.12  ? 756 ASN A OD1 1 
ATOM   5847  N  ND2 . ASN A 1 756 ? 228.778 198.579 151.673 1.00 89.12  ? 756 ASN A ND2 1 
ATOM   5848  N  N   . LEU A 1 757 ? 224.091 199.536 155.246 1.00 79.21  ? 757 LEU A N   1 
ATOM   5849  C  CA  . LEU A 1 757 ? 223.435 199.502 156.555 1.00 79.21  ? 757 LEU A CA  1 
ATOM   5850  C  C   . LEU A 1 757 ? 222.047 198.892 156.383 1.00 79.21  ? 757 LEU A C   1 
ATOM   5851  O  O   . LEU A 1 757 ? 221.256 199.372 155.566 1.00 79.21  ? 757 LEU A O   1 
ATOM   5852  C  CB  . LEU A 1 757 ? 223.355 200.903 157.146 1.00 79.21  ? 757 LEU A CB  1 
ATOM   5853  C  CG  . LEU A 1 757 ? 224.706 201.608 157.241 1.00 79.21  ? 757 LEU A CG  1 
ATOM   5854  C  CD1 . LEU A 1 757 ? 224.548 202.893 157.995 1.00 79.21  ? 757 LEU A CD1 1 
ATOM   5855  C  CD2 . LEU A 1 757 ? 225.742 200.728 157.919 1.00 79.21  ? 757 LEU A CD2 1 
ATOM   5856  N  N   . THR A 1 758 ? 221.738 197.841 157.143 1.00 64.18  ? 758 THR A N   1 
ATOM   5857  C  CA  . THR A 1 758 ? 220.503 197.115 156.900 1.00 64.18  ? 758 THR A CA  1 
ATOM   5858  C  C   . THR A 1 758 ? 219.442 197.417 157.957 1.00 64.18  ? 758 THR A C   1 
ATOM   5859  O  O   . THR A 1 758 ? 219.719 197.886 159.067 1.00 64.18  ? 758 THR A O   1 
ATOM   5860  C  CB  . THR A 1 758 ? 220.780 195.617 156.823 1.00 64.18  ? 758 THR A CB  1 
ATOM   5861  O  OG1 . THR A 1 758 ? 221.226 195.145 158.097 1.00 64.18  ? 758 THR A OG1 1 
ATOM   5862  C  CG2 . THR A 1 758 ? 221.848 195.330 155.780 1.00 64.18  ? 758 THR A CG2 1 
ATOM   5863  N  N   . VAL A 1 759 ? 218.198 197.132 157.599 1.00 56.34  ? 759 VAL A N   1 
ATOM   5864  C  CA  . VAL A 1 759 ? 217.067 197.308 158.494 1.00 56.34  ? 759 VAL A CA  1 
ATOM   5865  C  C   . VAL A 1 759 ? 216.246 196.028 158.485 1.00 56.34  ? 759 VAL A C   1 
ATOM   5866  O  O   . VAL A 1 759 ? 216.074 195.382 157.446 1.00 56.34  ? 759 VAL A O   1 
ATOM   5867  C  CB  . VAL A 1 759 ? 216.216 198.529 158.101 1.00 56.34  ? 759 VAL A CB  1 
ATOM   5868  C  CG1 . VAL A 1 759 ? 215.627 198.348 156.716 1.00 56.34  ? 759 VAL A CG1 1 
ATOM   5869  C  CG2 . VAL A 1 759 ? 215.114 198.740 159.100 1.00 56.34  ? 759 VAL A CG2 1 
ATOM   5870  N  N   . VAL A 1 760 ? 215.761 195.644 159.662 1.00 53.98  ? 760 VAL A N   1 
ATOM   5871  C  CA  . VAL A 1 760 ? 215.075 194.371 159.850 1.00 53.98  ? 760 VAL A CA  1 
ATOM   5872  C  C   . VAL A 1 760 ? 213.662 194.643 160.338 1.00 53.98  ? 760 VAL A C   1 
ATOM   5873  O  O   . VAL A 1 760 ? 213.465 195.037 161.493 1.00 53.98  ? 760 VAL A O   1 
ATOM   5874  C  CB  . VAL A 1 760 ? 215.819 193.463 160.836 1.00 53.98  ? 760 VAL A CB  1 
ATOM   5875  C  CG1 . VAL A 1 760 ? 214.951 192.286 161.219 1.00 53.98  ? 760 VAL A CG1 1 
ATOM   5876  C  CG2 . VAL A 1 760 ? 217.128 192.996 160.231 1.00 53.98  ? 760 VAL A CG2 1 
ATOM   5877  N  N   . ALA A 1 761 ? 212.680 194.421 159.475 1.00 61.64  ? 761 ALA A N   1 
ATOM   5878  C  CA  . ALA A 1 761 ? 211.285 194.454 159.880 1.00 61.64  ? 761 ALA A CA  1 
ATOM   5879  C  C   . ALA A 1 761 ? 210.897 193.104 160.469 1.00 61.64  ? 761 ALA A C   1 
ATOM   5880  O  O   . ALA A 1 761 ? 211.412 192.064 160.051 1.00 61.64  ? 761 ALA A O   1 
ATOM   5881  C  CB  . ALA A 1 761 ? 210.382 194.793 158.697 1.00 61.64  ? 761 ALA A CB  1 
ATOM   5882  N  N   . GLU A 1 762 ? 209.989 193.122 161.443 1.00 70.11  ? 762 GLU A N   1 
ATOM   5883  C  CA  . GLU A 1 762 ? 209.674 191.921 162.204 1.00 70.11  ? 762 GLU A CA  1 
ATOM   5884  C  C   . GLU A 1 762 ? 208.211 191.920 162.618 1.00 70.11  ? 762 GLU A C   1 
ATOM   5885  O  O   . GLU A 1 762 ? 207.657 192.954 162.997 1.00 70.11  ? 762 GLU A O   1 
ATOM   5886  C  CB  . GLU A 1 762 ? 210.567 191.804 163.445 1.00 70.11  ? 762 GLU A CB  1 
ATOM   5887  C  CG  . GLU A 1 762 ? 210.365 190.540 164.249 1.00 70.11  ? 762 GLU A CG  1 
ATOM   5888  C  CD  . GLU A 1 762 ? 209.379 190.729 165.381 1.00 70.11  ? 762 GLU A CD  1 
ATOM   5889  O  OE1 . GLU A 1 762 ? 209.391 191.811 166.003 1.00 70.11  ? 762 GLU A OE1 1 
ATOM   5890  O  OE2 . GLU A 1 762 ? 208.592 189.797 165.650 1.00 70.11  ? 762 GLU A OE2 1 
ATOM   5891  N  N   . GLY A 1 763 ? 207.597 190.740 162.570 1.00 75.38  ? 763 GLY A N   1 
ATOM   5892  C  CA  . GLY A 1 763 ? 206.224 190.583 163.008 1.00 75.38  ? 763 GLY A CA  1 
ATOM   5893  C  C   . GLY A 1 763 ? 205.225 190.469 161.879 1.00 75.38  ? 763 GLY A C   1 
ATOM   5894  O  O   . GLY A 1 763 ? 204.160 191.093 161.917 1.00 75.38  ? 763 GLY A O   1 
ATOM   5895  N  N   . VAL A 1 764 ? 205.551 189.677 160.873 1.00 76.64  ? 764 VAL A N   1 
ATOM   5896  C  CA  . VAL A 1 764 ? 204.727 189.548 159.679 1.00 76.64  ? 764 VAL A CA  1 
ATOM   5897  C  C   . VAL A 1 764 ? 203.804 188.347 159.827 1.00 76.64  ? 764 VAL A C   1 
ATOM   5898  O  O   . VAL A 1 764 ? 204.220 187.279 160.292 1.00 76.64  ? 764 VAL A O   1 
ATOM   5899  C  CB  . VAL A 1 764 ? 205.614 189.426 158.431 1.00 76.64  ? 764 VAL A CB  1 
ATOM   5900  C  CG1 . VAL A 1 764 ? 204.788 189.608 157.179 1.00 76.64  ? 764 VAL A CG1 1 
ATOM   5901  C  CG2 . VAL A 1 764 ? 206.703 190.459 158.496 1.00 76.64  ? 764 VAL A CG2 1 
ATOM   5902  N  N   . GLU A 1 765 ? 202.538 188.525 159.444 1.00 83.36  ? 765 GLU A N   1 
ATOM   5903  C  CA  . GLU A 1 765 ? 201.552 187.461 159.596 1.00 83.36  ? 765 GLU A CA  1 
ATOM   5904  C  C   . GLU A 1 765 ? 200.837 187.122 158.292 1.00 83.36  ? 765 GLU A C   1 
ATOM   5905  O  O   . GLU A 1 765 ? 200.605 185.945 158.003 1.00 83.36  ? 765 GLU A O   1 
ATOM   5906  C  CB  . GLU A 1 765 ? 200.524 187.845 160.661 1.00 83.36  ? 765 GLU A CB  1 
ATOM   5907  C  CG  . GLU A 1 765 ? 201.075 187.858 162.074 1.00 83.36  ? 765 GLU A CG  1 
ATOM   5908  C  CD  . GLU A 1 765 ? 199.984 187.801 163.126 1.00 83.36  ? 765 GLU A CD  1 
ATOM   5909  O  OE1 . GLU A 1 765 ? 198.880 188.327 162.870 1.00 83.36  ? 765 GLU A OE1 1 
ATOM   5910  O  OE2 . GLU A 1 765 ? 200.230 187.231 164.209 1.00 83.36  ? 765 GLU A OE2 1 
ATOM   5911  N  N   . THR A 1 766 ? 200.481 188.134 157.499 1.00 87.13  ? 766 THR A N   1 
ATOM   5912  C  CA  . THR A 1 766 ? 199.653 187.935 156.315 1.00 87.13  ? 766 THR A CA  1 
ATOM   5913  C  C   . THR A 1 766 ? 200.261 188.668 155.126 1.00 87.13  ? 766 THR A C   1 
ATOM   5914  O  O   . THR A 1 766 ? 201.172 189.491 155.266 1.00 87.13  ? 766 THR A O   1 
ATOM   5915  C  CB  . THR A 1 766 ? 198.215 188.417 156.538 1.00 87.13  ? 766 THR A CB  1 
ATOM   5916  O  OG1 . THR A 1 766 ? 198.204 189.844 156.630 1.00 87.13  ? 766 THR A OG1 1 
ATOM   5917  C  CG2 . THR A 1 766 ? 197.625 187.823 157.811 1.00 87.13  ? 766 THR A CG2 1 
ATOM   5918  N  N   . LYS A 1 767 ? 199.727 188.366 153.938 1.00 91.26  ? 767 LYS A N   1 
ATOM   5919  C  CA  . LYS A 1 767 ? 200.248 188.955 152.709 1.00 91.26  ? 767 LYS A CA  1 
ATOM   5920  C  C   . LYS A 1 767 ? 199.917 190.437 152.600 1.00 91.26  ? 767 LYS A C   1 
ATOM   5921  O  O   . LYS A 1 767 ? 200.690 191.195 152.006 1.00 91.26  ? 767 LYS A O   1 
ATOM   5922  C  CB  . LYS A 1 767 ? 199.706 188.207 151.491 1.00 91.26  ? 767 LYS A CB  1 
ATOM   5923  C  CG  . LYS A 1 767 ? 200.450 186.924 151.169 1.00 91.26  ? 767 LYS A CG  1 
ATOM   5924  C  CD  . LYS A 1 767 ? 200.184 186.479 149.741 1.00 91.26  ? 767 LYS A CD  1 
ATOM   5925  C  CE  . LYS A 1 767 ? 200.911 187.364 148.743 1.00 91.26  ? 767 LYS A CE  1 
ATOM   5926  N  NZ  . LYS A 1 767 ? 200.779 186.856 147.350 1.00 91.26  ? 767 LYS A NZ  1 
ATOM   5927  N  N   . GLU A 1 768 ? 198.779 190.871 153.147 1.00 94.44  ? 768 GLU A N   1 
ATOM   5928  C  CA  . GLU A 1 768 ? 198.447 192.291 153.085 1.00 94.44  ? 768 GLU A CA  1 
ATOM   5929  C  C   . GLU A 1 768 ? 199.436 193.127 153.885 1.00 94.44  ? 768 GLU A C   1 
ATOM   5930  O  O   . GLU A 1 768 ? 199.710 194.277 153.524 1.00 94.44  ? 768 GLU A O   1 
ATOM   5931  C  CB  . GLU A 1 768 ? 197.016 192.528 153.573 1.00 94.44  ? 768 GLU A CB  1 
ATOM   5932  C  CG  . GLU A 1 768 ? 196.706 191.944 154.937 1.00 94.44  ? 768 GLU A CG  1 
ATOM   5933  C  CD  . GLU A 1 768 ? 195.481 192.569 155.575 1.00 94.44  ? 768 GLU A CD  1 
ATOM   5934  O  OE1 . GLU A 1 768 ? 194.490 192.806 154.854 1.00 94.44  ? 768 GLU A OE1 1 
ATOM   5935  O  OE2 . GLU A 1 768 ? 195.510 192.822 156.798 1.00 94.44  ? 768 GLU A OE2 1 
ATOM   5936  N  N   . GLN A 1 769 ? 199.984 192.570 154.967 1.00 92.60  ? 769 GLN A N   1 
ATOM   5937  C  CA  . GLN A 1 769 ? 201.041 193.260 155.697 1.00 92.60  ? 769 GLN A CA  1 
ATOM   5938  C  C   . GLN A 1 769 ? 202.397 193.070 155.030 1.00 92.60  ? 769 GLN A C   1 
ATOM   5939  O  O   . GLN A 1 769 ? 203.221 193.990 155.028 1.00 92.60  ? 769 GLN A O   1 
ATOM   5940  C  CB  . GLN A 1 769 ? 201.085 192.775 157.145 1.00 92.60  ? 769 GLN A CB  1 
ATOM   5941  C  CG  . GLN A 1 769 ? 200.071 193.452 158.052 1.00 92.60  ? 769 GLN A CG  1 
ATOM   5942  C  CD  . GLN A 1 769 ? 198.680 192.869 157.914 1.00 92.60  ? 769 GLN A CD  1 
ATOM   5943  O  OE1 . GLN A 1 769 ? 198.504 191.651 157.895 1.00 92.60  ? 769 GLN A OE1 1 
ATOM   5944  N  NE2 . GLN A 1 769 ? 197.681 193.738 157.818 1.00 92.60  ? 769 GLN A NE2 1 
ATOM   5945  N  N   . PHE A 1 770 ? 202.646 191.890 154.459 1.00 84.84  ? 770 PHE A N   1 
ATOM   5946  C  CA  . PHE A 1 770 ? 203.921 191.656 153.791 1.00 84.84  ? 770 PHE A CA  1 
ATOM   5947  C  C   . PHE A 1 770 ? 204.115 192.615 152.627 1.00 84.84  ? 770 PHE A C   1 
ATOM   5948  O  O   . PHE A 1 770 ? 205.185 193.213 152.472 1.00 84.84  ? 770 PHE A O   1 
ATOM   5949  C  CB  . PHE A 1 770 ? 204.009 190.217 153.296 1.00 84.84  ? 770 PHE A CB  1 
ATOM   5950  C  CG  . PHE A 1 770 ? 205.334 189.874 152.685 1.00 84.84  ? 770 PHE A CG  1 
ATOM   5951  C  CD1 . PHE A 1 770 ? 206.421 189.571 153.482 1.00 84.84  ? 770 PHE A CD1 1 
ATOM   5952  C  CD2 . PHE A 1 770 ? 205.501 189.883 151.312 1.00 84.84  ? 770 PHE A CD2 1 
ATOM   5953  C  CE1 . PHE A 1 770 ? 207.644 189.258 152.918 1.00 84.84  ? 770 PHE A CE1 1 
ATOM   5954  C  CE2 . PHE A 1 770 ? 206.720 189.576 150.745 1.00 84.84  ? 770 PHE A CE2 1 
ATOM   5955  C  CZ  . PHE A 1 770 ? 207.792 189.263 151.547 1.00 84.84  ? 770 PHE A CZ  1 
ATOM   5956  N  N   . GLU A 1 771 ? 203.089 192.769 151.788 1.00 93.36  ? 771 GLU A N   1 
ATOM   5957  C  CA  . GLU A 1 771 ? 203.204 193.662 150.642 1.00 93.36  ? 771 GLU A CA  1 
ATOM   5958  C  C   . GLU A 1 771 ? 203.288 195.118 151.076 1.00 93.36  ? 771 GLU A C   1 
ATOM   5959  O  O   . GLU A 1 771 ? 203.991 195.912 150.443 1.00 93.36  ? 771 GLU A O   1 
ATOM   5960  C  CB  . GLU A 1 771 ? 202.027 193.455 149.690 1.00 93.36  ? 771 GLU A CB  1 
ATOM   5961  C  CG  . GLU A 1 771 ? 202.082 192.149 148.911 1.00 93.36  ? 771 GLU A CG  1 
ATOM   5962  C  CD  . GLU A 1 771 ? 203.046 192.204 147.739 1.00 93.36  ? 771 GLU A CD  1 
ATOM   5963  O  OE1 . GLU A 1 771 ? 204.273 192.244 147.973 1.00 93.36  ? 771 GLU A OE1 1 
ATOM   5964  O  OE2 . GLU A 1 771 ? 202.576 192.204 146.582 1.00 93.36  ? 771 GLU A OE2 1 
ATOM   5965  N  N   . MET A 1 772 ? 202.592 195.486 152.150 1.00 92.71  ? 772 MET A N   1 
ATOM   5966  C  CA  . MET A 1 772 ? 202.709 196.843 152.668 1.00 92.71  ? 772 MET A CA  1 
ATOM   5967  C  C   . MET A 1 772 ? 204.128 197.123 153.137 1.00 92.71  ? 772 MET A C   1 
ATOM   5968  O  O   . MET A 1 772 ? 204.673 198.205 152.897 1.00 92.71  ? 772 MET A O   1 
ATOM   5969  C  CB  . MET A 1 772 ? 201.713 197.056 153.803 1.00 92.71  ? 772 MET A CB  1 
ATOM   5970  C  CG  . MET A 1 772 ? 201.666 198.475 154.318 1.00 92.71  ? 772 MET A CG  1 
ATOM   5971  S  SD  . MET A 1 772 ? 200.964 198.589 155.971 1.00 92.71  ? 772 MET A SD  1 
ATOM   5972  C  CE  . MET A 1 772 ? 200.441 200.300 155.978 1.00 92.71  ? 772 MET A CE  1 
ATOM   5973  N  N   . LEU A 1 773 ? 204.749 196.150 153.810 1.00 90.50  ? 773 LEU A N   1 
ATOM   5974  C  CA  . LEU A 1 773 ? 206.104 196.354 154.314 1.00 90.50  ? 773 LEU A CA  1 
ATOM   5975  C  C   . LEU A 1 773 ? 207.134 196.290 153.194 1.00 90.50  ? 773 LEU A C   1 
ATOM   5976  O  O   . LEU A 1 773 ? 208.201 196.907 153.288 1.00 90.50  ? 773 LEU A O   1 
ATOM   5977  C  CB  . LEU A 1 773 ? 206.427 195.322 155.394 1.00 90.50  ? 773 LEU A CB  1 
ATOM   5978  C  CG  . LEU A 1 773 ? 206.282 195.785 156.845 1.00 90.50  ? 773 LEU A CG  1 
ATOM   5979  C  CD1 . LEU A 1 773 ? 204.822 196.019 157.195 1.00 90.50  ? 773 LEU A CD1 1 
ATOM   5980  C  CD2 . LEU A 1 773 ? 206.897 194.766 157.784 1.00 90.50  ? 773 LEU A CD2 1 
ATOM   5981  N  N   . ARG A 1 774 ? 206.840 195.547 152.129 1.00 85.95  ? 774 ARG A N   1 
ATOM   5982  C  CA  . ARG A 1 774 ? 207.801 195.410 151.044 1.00 85.95  ? 774 ARG A CA  1 
ATOM   5983  C  C   . ARG A 1 774 ? 207.690 196.522 150.009 1.00 85.95  ? 774 ARG A C   1 
ATOM   5984  O  O   . ARG A 1 774 ? 208.689 196.834 149.352 1.00 85.95  ? 774 ARG A O   1 
ATOM   5985  C  CB  . ARG A 1 774 ? 207.640 194.044 150.370 1.00 85.95  ? 774 ARG A CB  1 
ATOM   5986  C  CG  . ARG A 1 774 ? 208.646 193.771 149.263 1.00 85.95  ? 774 ARG A CG  1 
ATOM   5987  C  CD  . ARG A 1 774 ? 208.459 192.391 148.675 1.00 85.95  ? 774 ARG A CD  1 
ATOM   5988  N  NE  . ARG A 1 774 ? 209.412 192.136 147.603 1.00 85.95  ? 774 ARG A NE  1 
ATOM   5989  C  CZ  . ARG A 1 774 ? 209.192 192.429 146.329 1.00 85.95  ? 774 ARG A CZ  1 
ATOM   5990  N  NH1 . ARG A 1 774 ? 208.065 193.001 145.937 1.00 85.95  ? 774 ARG A NH1 1 
ATOM   5991  N  NH2 . ARG A 1 774 ? 210.126 192.145 145.426 1.00 85.95  ? 774 ARG A NH2 1 
ATOM   5992  N  N   . LYS A 1 775 ? 206.515 197.137 149.854 1.00 90.39  ? 775 LYS A N   1 
ATOM   5993  C  CA  . LYS A 1 775 ? 206.371 198.202 148.870 1.00 90.39  ? 775 LYS A CA  1 
ATOM   5994  C  C   . LYS A 1 775 ? 207.300 199.366 149.165 1.00 90.39  ? 775 LYS A C   1 
ATOM   5995  O  O   . LYS A 1 775 ? 207.677 200.098 148.244 1.00 90.39  ? 775 LYS A O   1 
ATOM   5996  C  CB  . LYS A 1 775 ? 204.919 198.684 148.811 1.00 90.39  ? 775 LYS A CB  1 
ATOM   5997  C  CG  . LYS A 1 775 ? 204.474 199.500 150.013 1.00 90.39  ? 775 LYS A CG  1 
ATOM   5998  C  CD  . LYS A 1 775 ? 203.315 200.420 149.661 1.00 90.39  ? 775 LYS A CD  1 
ATOM   5999  C  CE  . LYS A 1 775 ? 202.035 199.638 149.418 1.00 90.39  ? 775 LYS A CE  1 
ATOM   6000  N  NZ  . LYS A 1 775 ? 201.389 199.219 150.692 1.00 90.39  ? 775 LYS A NZ  1 
ATOM   6001  N  N   . ILE A 1 776 ? 207.681 199.544 150.423 1.00 82.38  ? 776 ILE A N   1 
ATOM   6002  C  CA  . ILE A 1 776 ? 208.725 200.475 150.817 1.00 82.38  ? 776 ILE A CA  1 
ATOM   6003  C  C   . ILE A 1 776 ? 209.981 199.656 151.068 1.00 82.38  ? 776 ILE A C   1 
ATOM   6004  O  O   . ILE A 1 776 ? 209.928 198.624 151.748 1.00 82.38  ? 776 ILE A O   1 
ATOM   6005  C  CB  . ILE A 1 776 ? 208.311 201.288 152.052 1.00 82.38  ? 776 ILE A CB  1 
ATOM   6006  C  CG1 . ILE A 1 776 ? 207.730 200.371 153.123 1.00 82.38  ? 776 ILE A CG1 1 
ATOM   6007  C  CG2 . ILE A 1 776 ? 207.290 202.335 151.662 1.00 82.38  ? 776 ILE A CG2 1 
ATOM   6008  C  CD1 . ILE A 1 776 ? 207.191 201.110 154.321 1.00 82.38  ? 776 ILE A CD1 1 
ATOM   6009  N  N   . HIS A 1 777 ? 211.098 200.100 150.502 1.00 79.19  ? 777 HIS A N   1 
ATOM   6010  C  CA  . HIS A 1 777 ? 212.293 199.273 150.442 1.00 79.19  ? 777 HIS A CA  1 
ATOM   6011  C  C   . HIS A 1 777 ? 212.780 198.906 151.835 1.00 79.19  ? 777 HIS A C   1 
ATOM   6012  O  O   . HIS A 1 777 ? 213.304 199.751 152.567 1.00 79.19  ? 777 HIS A O   1 
ATOM   6013  C  CB  . HIS A 1 777 ? 213.385 200.011 149.670 1.00 79.19  ? 777 HIS A CB  1 
ATOM   6014  C  CG  . HIS A 1 777 ? 214.568 199.160 149.337 1.00 79.19  ? 777 HIS A CG  1 
ATOM   6015  N  ND1 . HIS A 1 777 ? 214.541 198.203 148.346 1.00 79.19  ? 777 HIS A ND1 1 
ATOM   6016  C  CD2 . HIS A 1 777 ? 215.814 199.120 149.865 1.00 79.19  ? 777 HIS A CD2 1 
ATOM   6017  C  CE1 . HIS A 1 777 ? 215.720 197.611 148.276 1.00 79.19  ? 777 HIS A CE1 1 
ATOM   6018  N  NE2 . HIS A 1 777 ? 216.511 198.148 149.187 1.00 79.19  ? 777 HIS A NE2 1 
ATOM   6019  N  N   . CYS A 1 778 ? 212.604 197.635 152.193 1.00 66.92  ? 778 CYS A N   1 
ATOM   6020  C  CA  . CYS A 1 778 ? 213.059 197.097 153.472 1.00 66.92  ? 778 CYS A CA  1 
ATOM   6021  C  C   . CYS A 1 778 ? 213.849 195.836 153.166 1.00 66.92  ? 778 CYS A C   1 
ATOM   6022  O  O   . CYS A 1 778 ? 213.339 194.935 152.497 1.00 66.92  ? 778 CYS A O   1 
ATOM   6023  C  CB  . CYS A 1 778 ? 211.884 196.801 154.402 1.00 66.92  ? 778 CYS A CB  1 
ATOM   6024  S  SG  . CYS A 1 778 ? 212.349 196.037 155.964 1.00 66.92  ? 778 CYS A SG  1 
ATOM   6025  N  N   . ARG A 1 779 ? 215.089 195.776 153.645 1.00 66.85  ? 779 ARG A N   1 
ATOM   6026  C  CA  . ARG A 1 779 ? 216.011 194.738 153.194 1.00 66.85  ? 779 ARG A CA  1 
ATOM   6027  C  C   . ARG A 1 779 ? 215.576 193.347 153.649 1.00 66.85  ? 779 ARG A C   1 
ATOM   6028  O  O   . ARG A 1 779 ? 215.499 192.416 152.839 1.00 66.85  ? 779 ARG A O   1 
ATOM   6029  C  CB  . ARG A 1 779 ? 217.418 195.047 153.698 1.00 66.85  ? 779 ARG A CB  1 
ATOM   6030  C  CG  . ARG A 1 779 ? 217.992 196.331 153.159 1.00 66.85  ? 779 ARG A CG  1 
ATOM   6031  C  CD  . ARG A 1 779 ? 218.275 196.199 151.682 1.00 66.85  ? 779 ARG A CD  1 
ATOM   6032  N  NE  . ARG A 1 779 ? 219.188 195.096 151.413 1.00 66.85  ? 779 ARG A NE  1 
ATOM   6033  C  CZ  . ARG A 1 779 ? 220.504 195.158 151.566 1.00 66.85  ? 779 ARG A CZ  1 
ATOM   6034  N  NH1 . ARG A 1 779 ? 221.100 196.263 151.982 1.00 66.85  ? 779 ARG A NH1 1 
ATOM   6035  N  NH2 . ARG A 1 779 ? 221.240 194.084 151.294 1.00 66.85  ? 779 ARG A NH2 1 
ATOM   6036  N  N   . VAL A 1 780 ? 215.292 193.182 154.939 1.00 57.27  ? 780 VAL A N   1 
ATOM   6037  C  CA  . VAL A 1 780 ? 215.136 191.862 155.541 1.00 57.27  ? 780 VAL A CA  1 
ATOM   6038  C  C   . VAL A 1 780 ? 213.795 191.781 156.254 1.00 57.27  ? 780 VAL A C   1 
ATOM   6039  O  O   . VAL A 1 780 ? 213.439 192.681 157.021 1.00 57.27  ? 780 VAL A O   1 
ATOM   6040  C  CB  . VAL A 1 780 ? 216.283 191.556 156.516 1.00 57.27  ? 780 VAL A CB  1 
ATOM   6041  C  CG1 . VAL A 1 780 ? 216.114 190.177 157.120 1.00 57.27  ? 780 VAL A CG1 1 
ATOM   6042  C  CG2 . VAL A 1 780 ? 217.608 191.669 155.802 1.00 57.27  ? 780 VAL A CG2 1 
ATOM   6043  N  N   . ILE A 1 781 ? 213.062 190.693 156.012 1.00 54.90  ? 781 ILE A N   1 
ATOM   6044  C  CA  . ILE A 1 781 ? 211.768 190.431 156.629 1.00 54.90  ? 781 ILE A CA  1 
ATOM   6045  C  C   . ILE A 1 781 ? 211.849 189.130 157.418 1.00 54.90  ? 781 ILE A C   1 
ATOM   6046  O  O   . ILE A 1 781 ? 212.447 188.152 156.960 1.00 54.90  ? 781 ILE A O   1 
ATOM   6047  C  CB  . ILE A 1 781 ? 210.652 190.364 155.571 1.00 54.90  ? 781 ILE A CB  1 
ATOM   6048  C  CG1 . ILE A 1 781 ? 210.687 191.607 154.687 1.00 54.90  ? 781 ILE A CG1 1 
ATOM   6049  C  CG2 . ILE A 1 781 ? 209.315 190.240 156.229 1.00 54.90  ? 781 ILE A CG2 1 
ATOM   6050  C  CD1 . ILE A 1 781 ? 210.403 192.887 155.433 1.00 54.90  ? 781 ILE A CD1 1 
ATOM   6051  N  N   . GLN A 1 782 ? 211.251 189.126 158.607 1.00 55.57  ? 782 GLN A N   1 
ATOM   6052  C  CA  . GLN A 1 782 ? 211.379 188.027 159.557 1.00 55.57  ? 782 GLN A CA  1 
ATOM   6053  C  C   . GLN A 1 782 ? 210.147 188.008 160.449 1.00 55.57  ? 782 GLN A C   1 
ATOM   6054  O  O   . GLN A 1 782 ? 209.706 189.066 160.902 1.00 55.57  ? 782 GLN A O   1 
ATOM   6055  C  CB  . GLN A 1 782 ? 212.639 188.207 160.401 1.00 55.57  ? 782 GLN A CB  1 
ATOM   6056  C  CG  . GLN A 1 782 ? 212.753 187.281 161.583 1.00 55.57  ? 782 GLN A CG  1 
ATOM   6057  C  CD  . GLN A 1 782 ? 213.852 187.706 162.538 1.00 55.57  ? 782 GLN A CD  1 
ATOM   6058  O  OE1 . GLN A 1 782 ? 214.489 188.739 162.348 1.00 55.57  ? 782 GLN A OE1 1 
ATOM   6059  N  NE2 . GLN A 1 782 ? 214.075 186.910 163.574 1.00 55.57  ? 782 GLN A NE2 1 
ATOM   6060  N  N   . GLY A 1 783 ? 209.597 186.826 160.706 1.00 66.54  ? 783 GLY A N   1 
ATOM   6061  C  CA  . GLY A 1 783 ? 208.433 186.741 161.566 1.00 66.54  ? 783 GLY A CA  1 
ATOM   6062  C  C   . GLY A 1 783 ? 207.665 185.450 161.360 1.00 66.54  ? 783 GLY A C   1 
ATOM   6063  O  O   . GLY A 1 783 ? 208.180 184.474 160.813 1.00 66.54  ? 783 GLY A O   1 
ATOM   6064  N  N   . TYR A 1 784 ? 206.411 185.473 161.829 1.00 71.42  ? 784 TYR A N   1 
ATOM   6065  C  CA  . TYR A 1 784 ? 205.564 184.281 161.795 1.00 71.42  ? 784 TYR A CA  1 
ATOM   6066  C  C   . TYR A 1 784 ? 205.152 183.923 160.372 1.00 71.42  ? 784 TYR A C   1 
ATOM   6067  O  O   . TYR A 1 784 ? 204.977 182.743 160.047 1.00 71.42  ? 784 TYR A O   1 
ATOM   6068  C  CB  . TYR A 1 784 ? 204.326 184.495 162.664 1.00 71.42  ? 784 TYR A CB  1 
ATOM   6069  C  CG  . TYR A 1 784 ? 204.536 184.183 164.126 1.00 71.42  ? 784 TYR A CG  1 
ATOM   6070  C  CD1 . TYR A 1 784 ? 205.134 182.995 164.524 1.00 71.42  ? 784 TYR A CD1 1 
ATOM   6071  C  CD2 . TYR A 1 784 ? 204.132 185.075 165.111 1.00 71.42  ? 784 TYR A CD2 1 
ATOM   6072  C  CE1 . TYR A 1 784 ? 205.326 182.706 165.861 1.00 71.42  ? 784 TYR A CE1 1 
ATOM   6073  C  CE2 . TYR A 1 784 ? 204.320 184.794 166.452 1.00 71.42  ? 784 TYR A CE2 1 
ATOM   6074  C  CZ  . TYR A 1 784 ? 204.917 183.608 166.821 1.00 71.42  ? 784 TYR A CZ  1 
ATOM   6075  O  OH  . TYR A 1 784 ? 205.107 183.322 168.153 1.00 71.42  ? 784 TYR A OH  1 
ATOM   6076  N  N   . PHE A 1 785 ? 204.996 184.931 159.513 1.00 71.05  ? 785 PHE A N   1 
ATOM   6077  C  CA  . PHE A 1 785 ? 204.634 184.705 158.120 1.00 71.05  ? 785 PHE A CA  1 
ATOM   6078  C  C   . PHE A 1 785 ? 205.584 183.737 157.438 1.00 71.05  ? 785 PHE A C   1 
ATOM   6079  O  O   . PHE A 1 785 ? 205.174 183.016 156.523 1.00 71.05  ? 785 PHE A O   1 
ATOM   6080  C  CB  . PHE A 1 785 ? 204.638 186.045 157.385 1.00 71.05  ? 785 PHE A CB  1 
ATOM   6081  C  CG  . PHE A 1 785 ? 204.076 185.996 155.995 1.00 71.05  ? 785 PHE A CG  1 
ATOM   6082  C  CD1 . PHE A 1 785 ? 202.717 186.122 155.775 1.00 71.05  ? 785 PHE A CD1 1 
ATOM   6083  C  CD2 . PHE A 1 785 ? 204.912 185.856 154.903 1.00 71.05  ? 785 PHE A CD2 1 
ATOM   6084  C  CE1 . PHE A 1 785 ? 202.201 186.093 154.498 1.00 71.05  ? 785 PHE A CE1 1 
ATOM   6085  C  CE2 . PHE A 1 785 ? 204.400 185.824 153.622 1.00 71.05  ? 785 PHE A CE2 1 
ATOM   6086  C  CZ  . PHE A 1 785 ? 203.042 185.943 153.422 1.00 71.05  ? 785 PHE A CZ  1 
ATOM   6087  N  N   . PHE A 1 786 ? 206.842 183.703 157.864 1.00 59.45  ? 786 PHE A N   1 
ATOM   6088  C  CA  . PHE A 1 786 ? 207.849 182.825 157.289 1.00 59.45  ? 786 PHE A CA  1 
ATOM   6089  C  C   . PHE A 1 786 ? 208.036 181.545 158.082 1.00 59.45  ? 786 PHE A C   1 
ATOM   6090  O  O   . PHE A 1 786 ? 208.046 180.461 157.496 1.00 59.45  ? 786 PHE A O   1 
ATOM   6091  C  CB  . PHE A 1 786 ? 209.187 183.558 157.189 1.00 59.45  ? 786 PHE A CB  1 
ATOM   6092  C  CG  . PHE A 1 786 ? 209.320 184.398 155.962 1.00 59.45  ? 786 PHE A CG  1 
ATOM   6093  C  CD1 . PHE A 1 786 ? 208.300 185.233 155.570 1.00 59.45  ? 786 PHE A CD1 1 
ATOM   6094  C  CD2 . PHE A 1 786 ? 210.466 184.358 155.207 1.00 59.45  ? 786 PHE A CD2 1 
ATOM   6095  C  CE1 . PHE A 1 786 ? 208.418 186.006 154.443 1.00 59.45  ? 786 PHE A CE1 1 
ATOM   6096  C  CE2 . PHE A 1 786 ? 210.587 185.130 154.085 1.00 59.45  ? 786 PHE A CE2 1 
ATOM   6097  C  CZ  . PHE A 1 786 ? 209.563 185.954 153.701 1.00 59.45  ? 786 PHE A CZ  1 
ATOM   6098  N  N   . SER A 1 787 ? 208.175 181.640 159.401 1.00 60.44  ? 787 SER A N   1 
ATOM   6099  C  CA  . SER A 1 787 ? 208.367 180.442 160.201 1.00 60.44  ? 787 SER A CA  1 
ATOM   6100  C  C   . SER A 1 787 ? 208.197 180.757 161.677 1.00 60.44  ? 787 SER A C   1 
ATOM   6101  O  O   . SER A 1 787 ? 208.676 181.783 162.160 1.00 60.44  ? 787 SER A O   1 
ATOM   6102  C  CB  . SER A 1 787 ? 209.753 179.837 159.970 1.00 60.44  ? 787 SER A CB  1 
ATOM   6103  O  OG  . SER A 1 787 ? 209.932 178.711 160.803 1.00 60.44  ? 787 SER A OG  1 
ATOM   6104  N  N   . ARG A 1 788 ? 207.515 179.860 162.376 1.00 62.79  ? 788 ARG A N   1 
ATOM   6105  C  CA  . ARG A 1 788 ? 207.594 179.809 163.820 1.00 62.79  ? 788 ARG A CA  1 
ATOM   6106  C  C   . ARG A 1 788 ? 209.010 179.397 164.223 1.00 62.79  ? 788 ARG A C   1 
ATOM   6107  O  O   . ARG A 1 788 ? 209.698 178.706 163.466 1.00 62.79  ? 788 ARG A O   1 
ATOM   6108  C  CB  . ARG A 1 788 ? 206.562 178.815 164.357 1.00 62.79  ? 788 ARG A CB  1 
ATOM   6109  C  CG  . ARG A 1 788 ? 206.653 178.462 165.835 1.00 62.79  ? 788 ARG A CG  1 
ATOM   6110  C  CD  . ARG A 1 788 ? 205.743 179.342 166.676 1.00 62.79  ? 788 ARG A CD  1 
ATOM   6111  N  NE  . ARG A 1 788 ? 205.409 178.724 167.953 1.00 62.79  ? 788 ARG A NE  1 
ATOM   6112  C  CZ  . ARG A 1 788 ? 206.185 178.757 169.028 1.00 62.79  ? 788 ARG A CZ  1 
ATOM   6113  N  NH1 . ARG A 1 788 ? 207.355 179.376 169.018 1.00 62.79  ? 788 ARG A NH1 1 
ATOM   6114  N  NH2 . ARG A 1 788 ? 205.777 178.156 170.142 1.00 62.79  ? 788 ARG A NH2 1 
ATOM   6115  N  N   . PRO A 1 789 ? 209.486 179.845 165.384 1.00 59.63  ? 789 PRO A N   1 
ATOM   6116  C  CA  . PRO A 1 789 ? 210.820 179.435 165.842 1.00 59.63  ? 789 PRO A CA  1 
ATOM   6117  C  C   . PRO A 1 789 ? 210.989 177.923 165.834 1.00 59.63  ? 789 PRO A C   1 
ATOM   6118  O  O   . PRO A 1 789 ? 210.334 177.202 166.588 1.00 59.63  ? 789 PRO A O   1 
ATOM   6119  C  CB  . PRO A 1 789 ? 210.888 180.004 167.260 1.00 59.63  ? 789 PRO A CB  1 
ATOM   6120  C  CG  . PRO A 1 789 ? 210.047 181.228 167.195 1.00 59.63  ? 789 PRO A CG  1 
ATOM   6121  C  CD  . PRO A 1 789 ? 208.948 180.953 166.196 1.00 59.63  ? 789 PRO A CD  1 
ATOM   6122  N  N   . LEU A 1 790 ? 211.882 177.453 164.972 1.00 57.50  ? 790 LEU A N   1 
ATOM   6123  C  CA  . LEU A 1 790 ? 212.181 176.031 164.850 1.00 57.50  ? 790 LEU A CA  1 
ATOM   6124  C  C   . LEU A 1 790 ? 212.868 175.529 166.111 1.00 57.50  ? 790 LEU A C   1 
ATOM   6125  O  O   . LEU A 1 790 ? 213.664 176.259 166.704 1.00 57.50  ? 790 LEU A O   1 
ATOM   6126  C  CB  . LEU A 1 790 ? 213.100 175.771 163.672 1.00 57.50  ? 790 LEU A CB  1 
ATOM   6127  C  CG  . LEU A 1 790 ? 212.588 175.846 162.247 1.00 57.50  ? 790 LEU A CG  1 
ATOM   6128  C  CD1 . LEU A 1 790 ? 212.464 177.285 161.822 1.00 57.50  ? 790 LEU A CD1 1 
ATOM   6129  C  CD2 . LEU A 1 790 ? 213.569 175.126 161.358 1.00 57.50  ? 790 LEU A CD2 1 
ATOM   6130  N  N   . PRO A 1 791 ? 212.612 174.297 166.532 1.00 58.88  ? 791 PRO A N   1 
ATOM   6131  C  CA  . PRO A 1 791 ? 213.455 173.694 167.571 1.00 58.88  ? 791 PRO A CA  1 
ATOM   6132  C  C   . PRO A 1 791 ? 214.892 173.579 167.101 1.00 58.88  ? 791 PRO A C   1 
ATOM   6133  O  O   . PRO A 1 791 ? 215.200 173.867 165.943 1.00 58.88  ? 791 PRO A O   1 
ATOM   6134  C  CB  . PRO A 1 791 ? 212.816 172.318 167.806 1.00 58.88  ? 791 PRO A CB  1 
ATOM   6135  C  CG  . PRO A 1 791 ? 211.864 172.110 166.672 1.00 58.88  ? 791 PRO A CG  1 
ATOM   6136  C  CD  . PRO A 1 791 ? 211.439 173.467 166.219 1.00 58.88  ? 791 PRO A CD  1 
ATOM   6137  N  N   . ALA A 1 792 ? 215.775 173.144 167.992 1.00 57.84  ? 792 ALA A N   1 
ATOM   6138  C  CA  . ALA A 1 792 ? 217.204 173.288 167.748 1.00 57.84  ? 792 ALA A CA  1 
ATOM   6139  C  C   . ALA A 1 792 ? 217.647 172.517 166.514 1.00 57.84  ? 792 ALA A C   1 
ATOM   6140  O  O   . ALA A 1 792 ? 218.429 173.021 165.701 1.00 57.84  ? 792 ALA A O   1 
ATOM   6141  C  CB  . ALA A 1 792 ? 217.990 172.830 168.976 1.00 57.84  ? 792 ALA A CB  1 
ATOM   6142  N  N   . GLU A 1 793 ? 217.157 171.295 166.351 1.00 61.58  ? 793 GLU A N   1 
ATOM   6143  C  CA  . GLU A 1 793 ? 217.779 170.392 165.396 1.00 61.58  ? 793 GLU A CA  1 
ATOM   6144  C  C   . GLU A 1 793 ? 217.217 170.494 163.987 1.00 61.58  ? 793 GLU A C   1 
ATOM   6145  O  O   . GLU A 1 793 ? 217.713 169.798 163.096 1.00 61.58  ? 793 GLU A O   1 
ATOM   6146  C  CB  . GLU A 1 793 ? 217.646 168.954 165.892 1.00 61.58  ? 793 GLU A CB  1 
ATOM   6147  C  CG  . GLU A 1 793 ? 218.299 168.710 167.231 1.00 61.58  ? 793 GLU A CG  1 
ATOM   6148  C  CD  . GLU A 1 793 ? 219.810 168.721 167.149 1.00 61.58  ? 793 GLU A CD  1 
ATOM   6149  O  OE1 . GLU A 1 793 ? 220.347 168.652 166.025 1.00 61.58  ? 793 GLU A OE1 1 
ATOM   6150  O  OE2 . GLU A 1 793 ? 220.462 168.795 168.211 1.00 61.58  ? 793 GLU A OE2 1 
ATOM   6151  N  N   . GLU A 1 794 ? 216.210 171.326 163.746 1.00 63.33  ? 794 GLU A N   1 
ATOM   6152  C  CA  . GLU A 1 794 ? 215.591 171.298 162.428 1.00 63.33  ? 794 GLU A CA  1 
ATOM   6153  C  C   . GLU A 1 794 ? 216.393 172.057 161.382 1.00 63.33  ? 794 GLU A C   1 
ATOM   6154  O  O   . GLU A 1 794 ? 216.321 171.715 160.199 1.00 63.33  ? 794 GLU A O   1 
ATOM   6155  C  CB  . GLU A 1 794 ? 214.165 171.845 162.488 1.00 63.33  ? 794 GLU A CB  1 
ATOM   6156  C  CG  . GLU A 1 794 ? 213.235 171.086 163.419 1.00 63.33  ? 794 GLU A CG  1 
ATOM   6157  C  CD  . GLU A 1 794 ? 211.800 171.570 163.323 1.00 63.33  ? 794 GLU A CD  1 
ATOM   6158  O  OE1 . GLU A 1 794 ? 211.592 172.778 163.081 1.00 63.33  ? 794 GLU A OE1 1 
ATOM   6159  O  OE2 . GLU A 1 794 ? 210.879 170.744 163.495 1.00 63.33  ? 794 GLU A OE2 1 
ATOM   6160  N  N   . ILE A 1 795 ? 217.149 173.084 161.779 1.00 67.14  ? 795 ILE A N   1 
ATOM   6161  C  CA  . ILE A 1 795 ? 217.832 173.925 160.789 1.00 67.14  ? 795 ILE A CA  1 
ATOM   6162  C  C   . ILE A 1 795 ? 218.804 173.153 159.911 1.00 67.14  ? 795 ILE A C   1 
ATOM   6163  O  O   . ILE A 1 795 ? 218.804 173.377 158.694 1.00 67.14  ? 795 ILE A O   1 
ATOM   6164  C  CB  . ILE A 1 795 ? 218.468 175.142 161.473 1.00 67.14  ? 795 ILE A CB  1 
ATOM   6165  C  CG1 . ILE A 1 795 ? 217.384 176.157 161.826 1.00 67.14  ? 795 ILE A CG1 1 
ATOM   6166  C  CG2 . ILE A 1 795 ? 219.534 175.767 160.598 1.00 67.14  ? 795 ILE A CG2 1 
ATOM   6167  C  CD1 . ILE A 1 795 ? 217.890 177.357 162.554 1.00 67.14  ? 795 ILE A CD1 1 
ATOM   6168  N  N   . PRO A 1 796 ? 219.645 172.243 160.424 1.00 71.95  ? 796 PRO A N   1 
ATOM   6169  C  CA  . PRO A 1 796 ? 220.540 171.499 159.524 1.00 71.95  ? 796 PRO A CA  1 
ATOM   6170  C  C   . PRO A 1 796 ? 219.819 170.798 158.380 1.00 71.95  ? 796 PRO A C   1 
ATOM   6171  O  O   . PRO A 1 796 ? 220.462 170.344 157.430 1.00 71.95  ? 796 PRO A O   1 
ATOM   6172  C  CB  . PRO A 1 796 ? 221.223 170.485 160.455 1.00 71.95  ? 796 PRO A CB  1 
ATOM   6173  C  CG  . PRO A 1 796 ? 220.525 170.597 161.778 1.00 71.95  ? 796 PRO A CG  1 
ATOM   6174  C  CD  . PRO A 1 796 ? 219.971 171.975 161.834 1.00 71.95  ? 796 PRO A CD  1 
ATOM   6175  N  N   . GLY A 1 797 ? 218.496 170.703 158.452 1.00 68.74  ? 797 GLY A N   1 
ATOM   6176  C  CA  . GLY A 1 797 ? 217.723 170.232 157.322 1.00 68.74  ? 797 GLY A CA  1 
ATOM   6177  C  C   . GLY A 1 797 ? 216.994 171.352 156.608 1.00 68.74  ? 797 GLY A C   1 
ATOM   6178  O  O   . GLY A 1 797 ? 216.917 171.373 155.376 1.00 68.74  ? 797 GLY A O   1 
ATOM   6179  N  N   . TRP A 1 798 ? 216.448 172.289 157.384 1.00 66.95  ? 798 TRP A N   1 
ATOM   6180  C  CA  . TRP A 1 798 ? 215.679 173.388 156.812 1.00 66.95  ? 798 TRP A CA  1 
ATOM   6181  C  C   . TRP A 1 798 ? 216.538 174.225 155.875 1.00 66.95  ? 798 TRP A C   1 
ATOM   6182  O  O   . TRP A 1 798 ? 216.114 174.574 154.768 1.00 66.95  ? 798 TRP A O   1 
ATOM   6183  C  CB  . TRP A 1 798 ? 215.102 174.246 157.943 1.00 66.95  ? 798 TRP A CB  1 
ATOM   6184  C  CG  . TRP A 1 798 ? 214.457 175.547 157.531 1.00 66.95  ? 798 TRP A CG  1 
ATOM   6185  C  CD1 . TRP A 1 798 ? 215.055 176.606 156.909 1.00 66.95  ? 798 TRP A CD1 1 
ATOM   6186  C  CD2 . TRP A 1 798 ? 213.105 175.945 157.776 1.00 66.95  ? 798 TRP A CD2 1 
ATOM   6187  N  NE1 . TRP A 1 798 ? 214.152 177.617 156.720 1.00 66.95  ? 798 TRP A NE1 1 
ATOM   6188  C  CE2 . TRP A 1 798 ? 212.947 177.238 157.245 1.00 66.95  ? 798 TRP A CE2 1 
ATOM   6189  C  CE3 . TRP A 1 798 ? 212.007 175.326 158.373 1.00 66.95  ? 798 TRP A CE3 1 
ATOM   6190  C  CZ2 . TRP A 1 798 ? 211.742 177.923 157.300 1.00 66.95  ? 798 TRP A CZ2 1 
ATOM   6191  C  CZ3 . TRP A 1 798 ? 210.812 176.009 158.428 1.00 66.95  ? 798 TRP A CZ3 1 
ATOM   6192  C  CH2 . TRP A 1 798 ? 210.688 177.292 157.892 1.00 66.95  ? 798 TRP A CH2 1 
ATOM   6193  N  N   . MET A 1 799 ? 217.746 174.579 156.316 1.00 74.98  ? 799 MET A N   1 
ATOM   6194  C  CA  . MET A 1 799 ? 218.632 175.381 155.480 1.00 74.98  ? 799 MET A CA  1 
ATOM   6195  C  C   . MET A 1 799 ? 219.043 174.621 154.228 1.00 74.98  ? 799 MET A C   1 
ATOM   6196  O  O   . MET A 1 799 ? 219.094 175.195 153.134 1.00 74.98  ? 799 MET A O   1 
ATOM   6197  C  CB  . MET A 1 799 ? 219.866 175.811 156.274 1.00 74.98  ? 799 MET A CB  1 
ATOM   6198  C  CG  . MET A 1 799 ? 220.798 176.734 155.502 1.00 74.98  ? 799 MET A CG  1 
ATOM   6199  S  SD  . MET A 1 799 ? 222.295 177.169 156.408 1.00 74.98  ? 799 MET A SD  1 
ATOM   6200  C  CE  . MET A 1 799 ? 221.652 178.334 157.605 1.00 74.98  ? 799 MET A CE  1 
ATOM   6201  N  N   . SER A 1 800 ? 219.341 173.327 154.369 1.00 73.87  ? 800 SER A N   1 
ATOM   6202  C  CA  . SER A 1 800 ? 219.710 172.524 153.210 1.00 73.87  ? 800 SER A CA  1 
ATOM   6203  C  C   . SER A 1 800 ? 218.567 172.433 152.211 1.00 73.87  ? 800 SER A C   1 
ATOM   6204  O  O   . SER A 1 800 ? 218.800 172.401 150.998 1.00 73.87  ? 800 SER A O   1 
ATOM   6205  C  CB  . SER A 1 800 ? 220.139 171.128 153.657 1.00 73.87  ? 800 SER A CB  1 
ATOM   6206  O  OG  . SER A 1 800 ? 221.157 171.199 154.640 1.00 73.87  ? 800 SER A OG  1 
ATOM   6207  N  N   . SER A 1 801 ? 217.328 172.402 152.699 1.00 68.23  ? 801 SER A N   1 
ATOM   6208  C  CA  . SER A 1 801 ? 216.158 172.291 151.838 1.00 68.23  ? 801 SER A CA  1 
ATOM   6209  C  C   . SER A 1 801 ? 215.823 173.614 151.162 1.00 68.23  ? 801 SER A C   1 
ATOM   6210  O  O   . SER A 1 801 ? 215.891 173.722 149.935 1.00 68.23  ? 801 SER A O   1 
ATOM   6211  C  CB  . SER A 1 801 ? 214.957 171.797 152.653 1.00 68.23  ? 801 SER A CB  1 
ATOM   6212  O  OG  . SER A 1 801 ? 214.565 172.768 153.605 1.00 68.23  ? 801 SER A OG  1 
ATOM   6213  N  N   . VAL A 1 802 ? 215.476 174.632 151.945 1.00 68.14  ? 802 VAL A N   1 
ATOM   6214  C  CA  . VAL A 1 802 ? 214.964 175.879 151.390 1.00 68.14  ? 802 VAL A CA  1 
ATOM   6215  C  C   . VAL A 1 802 ? 216.110 176.831 151.088 1.00 68.14  ? 802 VAL A C   1 
ATOM   6216  O  O   . VAL A 1 802 ? 216.650 177.480 151.989 1.00 68.14  ? 802 VAL A O   1 
ATOM   6217  C  CB  . VAL A 1 802 ? 213.946 176.537 152.336 1.00 68.14  ? 802 VAL A CB  1 
ATOM   6218  C  CG1 . VAL A 1 802 ? 213.406 177.807 151.715 1.00 68.14  ? 802 VAL A CG1 1 
ATOM   6219  C  CG2 . VAL A 1 802 ? 212.815 175.573 152.642 1.00 68.14  ? 802 VAL A CG2 1 
ATOM   6220  N  N   . LEU A 1 803 ? 216.480 176.918 149.815 1.00 74.79  ? 803 LEU A N   1 
ATOM   6221  C  CA  . LEU A 1 803 ? 217.474 177.883 149.348 1.00 74.79  ? 803 LEU A CA  1 
ATOM   6222  C  C   . LEU A 1 803 ? 217.214 178.136 147.870 1.00 74.79  ? 803 LEU A C   1 
ATOM   6223  O  O   . LEU A 1 803 ? 217.677 177.371 147.010 1.00 74.79  ? 803 LEU A O   1 
ATOM   6224  C  CB  . LEU A 1 803 ? 218.901 177.387 149.570 1.00 74.79  ? 803 LEU A CB  1 
ATOM   6225  C  CG  . LEU A 1 803 ? 219.597 177.727 150.888 1.00 74.79  ? 803 LEU A CG  1 
ATOM   6226  C  CD1 . LEU A 1 803 ? 220.893 176.942 151.024 1.00 74.79  ? 803 LEU A CD1 1 
ATOM   6227  C  CD2 . LEU A 1 803 ? 219.860 179.222 150.985 1.00 74.79  ? 803 LEU A CD2 1 
ATOM   6228  N  N   . PRO A 1 804 ? 216.477 179.201 147.528 1.00 70.71  ? 804 PRO A N   1 
ATOM   6229  C  CA  . PRO A 1 804 ? 215.768 180.148 148.391 1.00 70.71  ? 804 PRO A CA  1 
ATOM   6230  C  C   . PRO A 1 804 ? 214.322 179.742 148.627 1.00 70.71  ? 804 PRO A C   1 
ATOM   6231  O  O   . PRO A 1 804 ? 213.953 178.587 148.449 1.00 70.71  ? 804 PRO A O   1 
ATOM   6232  C  CB  . PRO A 1 804 ? 215.866 181.449 147.594 1.00 70.71  ? 804 PRO A CB  1 
ATOM   6233  C  CG  . PRO A 1 804 ? 215.725 180.980 146.173 1.00 70.71  ? 804 PRO A CG  1 
ATOM   6234  C  CD  . PRO A 1 804 ? 216.413 179.626 146.117 1.00 70.71  ? 804 PRO A CD  1 
ATOM   6235  N  N   . LEU A 1 805 ? 213.482 180.688 149.049 1.00 68.07  ? 805 LEU A N   1 
ATOM   6236  C  CA  . LEU A 1 805 ? 212.047 180.472 149.135 1.00 68.07  ? 805 LEU A CA  1 
ATOM   6237  C  C   . LEU A 1 805 ? 211.245 181.244 148.102 1.00 68.07  ? 805 LEU A C   1 
ATOM   6238  O  O   . LEU A 1 805 ? 210.125 180.828 147.790 1.00 68.07  ? 805 LEU A O   1 
ATOM   6239  C  CB  . LEU A 1 805 ? 211.532 180.827 150.539 1.00 68.07  ? 805 LEU A CB  1 
ATOM   6240  C  CG  . LEU A 1 805 ? 211.744 182.235 151.095 1.00 68.07  ? 805 LEU A CG  1 
ATOM   6241  C  CD1 . LEU A 1 805 ? 210.652 183.208 150.667 1.00 68.07  ? 805 LEU A CD1 1 
ATOM   6242  C  CD2 . LEU A 1 805 ? 211.829 182.164 152.607 1.00 68.07  ? 805 LEU A CD2 1 
ATOM   6243  N  N   . LYS A 1 806 ? 211.776 182.344 147.572 1.00 76.23  ? 806 LYS A N   1 
ATOM   6244  C  CA  . LYS A 1 806 ? 211.109 183.150 146.549 1.00 76.23  ? 806 LYS A CA  1 
ATOM   6245  C  C   . LYS A 1 806 ? 209.725 183.633 146.983 1.00 76.23  ? 806 LYS A C   1 
ATOM   6246  O  O   . LYS A 1 806 ? 209.585 184.691 147.598 1.00 76.23  ? 806 LYS A O   1 
ATOM   6247  C  CB  . LYS A 1 806 ? 210.996 182.365 145.239 1.00 76.23  ? 806 LYS A CB  1 
ATOM   6248  C  CG  . LYS A 1 806 ? 210.715 183.232 144.022 1.00 76.23  ? 806 LYS A CG  1 
ATOM   6249  C  CD  . LYS A 1 806 ? 210.551 182.389 142.768 1.00 76.23  ? 806 LYS A CD  1 
ATOM   6250  C  CE  . LYS A 1 806 ? 211.878 181.796 142.323 1.00 76.23  ? 806 LYS A CE  1 
ATOM   6251  N  NZ  . LYS A 1 806 ? 212.795 182.836 141.781 1.00 76.23  ? 806 LYS A NZ  1 
ATOM   6252  N  N   . GLY B 1 20  ? 239.474 213.894 325.840 1.00 162.19 ? 20  GLY B N   1 
ATOM   6253  C  CA  . GLY B 1 20  ? 238.196 214.243 325.246 1.00 162.19 ? 20  GLY B CA  1 
ATOM   6254  C  C   . GLY B 1 20  ? 237.353 213.035 324.888 1.00 162.19 ? 20  GLY B C   1 
ATOM   6255  O  O   . GLY B 1 20  ? 237.755 212.207 324.071 1.00 162.19 ? 20  GLY B O   1 
ATOM   6256  N  N   . ILE B 1 21  ? 236.174 212.935 325.507 1.00 162.71 ? 21  ILE B N   1 
ATOM   6257  C  CA  . ILE B 1 21  ? 235.286 211.811 325.238 1.00 162.71 ? 21  ILE B CA  1 
ATOM   6258  C  C   . ILE B 1 21  ? 234.640 211.913 323.863 1.00 162.71 ? 21  ILE B C   1 
ATOM   6259  O  O   . ILE B 1 21  ? 234.214 210.894 323.307 1.00 162.71 ? 21  ILE B O   1 
ATOM   6260  C  CB  . ILE B 1 21  ? 234.210 211.700 326.335 1.00 162.71 ? 21  ILE B CB  1 
ATOM   6261  C  CG1 . ILE B 1 21  ? 233.325 212.949 326.347 1.00 162.71 ? 21  ILE B CG1 1 
ATOM   6262  C  CG2 . ILE B 1 21  ? 234.855 211.484 327.695 1.00 162.71 ? 21  ILE B CG2 1 
ATOM   6263  C  CD1 . ILE B 1 21  ? 232.088 212.812 327.208 1.00 162.71 ? 21  ILE B CD1 1 
ATOM   6264  N  N   . PHE B 1 22  ? 234.546 213.119 323.299 1.00 160.91 ? 22  PHE B N   1 
ATOM   6265  C  CA  . PHE B 1 22  ? 233.940 213.274 321.981 1.00 160.91 ? 22  PHE B CA  1 
ATOM   6266  C  C   . PHE B 1 22  ? 234.937 213.015 320.858 1.00 160.91 ? 22  PHE B C   1 
ATOM   6267  O  O   . PHE B 1 22  ? 234.533 212.884 319.697 1.00 160.91 ? 22  PHE B O   1 
ATOM   6268  C  CB  . PHE B 1 22  ? 233.342 214.674 321.838 1.00 160.91 ? 22  PHE B CB  1 
ATOM   6269  C  CG  . PHE B 1 22  ? 232.278 214.987 322.850 1.00 160.91 ? 22  PHE B CG  1 
ATOM   6270  C  CD1 . PHE B 1 22  ? 230.973 214.565 322.658 1.00 160.91 ? 22  PHE B CD1 1 
ATOM   6271  C  CD2 . PHE B 1 22  ? 232.583 215.711 323.991 1.00 160.91 ? 22  PHE B CD2 1 
ATOM   6272  C  CE1 . PHE B 1 22  ? 229.992 214.855 323.588 1.00 160.91 ? 22  PHE B CE1 1 
ATOM   6273  C  CE2 . PHE B 1 22  ? 231.607 216.004 324.924 1.00 160.91 ? 22  PHE B CE2 1 
ATOM   6274  C  CZ  . PHE B 1 22  ? 230.310 215.576 324.722 1.00 160.91 ? 22  PHE B CZ  1 
ATOM   6275  N  N   . PHE B 1 23  ? 236.230 212.952 321.174 1.00 154.20 ? 23  PHE B N   1 
ATOM   6276  C  CA  . PHE B 1 23  ? 237.229 212.646 320.152 1.00 154.20 ? 23  PHE B CA  1 
ATOM   6277  C  C   . PHE B 1 23  ? 237.025 211.276 319.517 1.00 154.20 ? 23  PHE B C   1 
ATOM   6278  O  O   . PHE B 1 23  ? 237.095 211.182 318.279 1.00 154.20 ? 23  PHE B O   1 
ATOM   6279  C  CB  . PHE B 1 23  ? 238.635 212.787 320.746 1.00 154.20 ? 23  PHE B CB  1 
ATOM   6280  C  CG  . PHE B 1 23  ? 239.732 212.343 319.821 1.00 154.20 ? 23  PHE B CG  1 
ATOM   6281  C  CD1 . PHE B 1 23  ? 240.139 213.148 318.769 1.00 154.20 ? 23  PHE B CD1 1 
ATOM   6282  C  CD2 . PHE B 1 23  ? 240.358 211.121 320.003 1.00 154.20 ? 23  PHE B CD2 1 
ATOM   6283  C  CE1 . PHE B 1 23  ? 241.149 212.742 317.917 1.00 154.20 ? 23  PHE B CE1 1 
ATOM   6284  C  CE2 . PHE B 1 23  ? 241.368 210.709 319.154 1.00 154.20 ? 23  PHE B CE2 1 
ATOM   6285  C  CZ  . PHE B 1 23  ? 241.764 211.520 318.110 1.00 154.20 ? 23  PHE B CZ  1 
ATOM   6286  N  N   . PRO B 1 24  ? 236.794 210.189 320.267 1.00 152.63 ? 24  PRO B N   1 
ATOM   6287  C  CA  . PRO B 1 24  ? 236.511 208.908 319.600 1.00 152.63 ? 24  PRO B CA  1 
ATOM   6288  C  C   . PRO B 1 24  ? 235.282 208.953 318.714 1.00 152.63 ? 24  PRO B C   1 
ATOM   6289  O  O   . PRO B 1 24  ? 235.220 208.219 317.718 1.00 152.63 ? 24  PRO B O   1 
ATOM   6290  C  CB  . PRO B 1 24  ? 236.326 207.934 320.771 1.00 152.63 ? 24  PRO B CB  1 
ATOM   6291  C  CG  . PRO B 1 24  ? 237.067 208.549 321.894 1.00 152.63 ? 24  PRO B CG  1 
ATOM   6292  C  CD  . PRO B 1 24  ? 236.890 210.024 321.729 1.00 152.63 ? 24  PRO B CD  1 
ATOM   6293  N  N   . ALA B 1 25  ? 234.298 209.790 319.049 1.00 152.31 ? 25  ALA B N   1 
ATOM   6294  C  CA  . ALA B 1 25  ? 233.141 209.951 318.177 1.00 152.31 ? 25  ALA B CA  1 
ATOM   6295  C  C   . ALA B 1 25  ? 233.567 210.442 316.804 1.00 152.31 ? 25  ALA B C   1 
ATOM   6296  O  O   . ALA B 1 25  ? 233.078 209.953 315.779 1.00 152.31 ? 25  ALA B O   1 
ATOM   6297  C  CB  . ALA B 1 25  ? 232.137 210.917 318.804 1.00 152.31 ? 25  ALA B CB  1 
ATOM   6298  N  N   . LEU B 1 26  ? 234.488 211.404 316.764 1.00 151.36 ? 26  LEU B N   1 
ATOM   6299  C  CA  . LEU B 1 26  ? 235.016 211.862 315.487 1.00 151.36 ? 26  LEU B CA  1 
ATOM   6300  C  C   . LEU B 1 26  ? 235.895 210.798 314.841 1.00 151.36 ? 26  LEU B C   1 
ATOM   6301  O  O   . LEU B 1 26  ? 235.893 210.640 313.614 1.00 151.36 ? 26  LEU B O   1 
ATOM   6302  C  CB  . LEU B 1 26  ? 235.797 213.159 315.686 1.00 151.36 ? 26  LEU B CB  1 
ATOM   6303  C  CG  . LEU B 1 26  ? 235.023 214.292 316.361 1.00 151.36 ? 26  LEU B CG  1 
ATOM   6304  C  CD1 . LEU B 1 26  ? 235.958 215.428 316.745 1.00 151.36 ? 26  LEU B CD1 1 
ATOM   6305  C  CD2 . LEU B 1 26  ? 233.906 214.791 315.457 1.00 151.36 ? 26  LEU B CD2 1 
ATOM   6306  N  N   . GLU B 1 27  ? 236.658 210.062 315.652 1.00 148.60 ? 27  GLU B N   1 
ATOM   6307  C  CA  . GLU B 1 27  ? 237.607 209.094 315.109 1.00 148.60 ? 27  GLU B CA  1 
ATOM   6308  C  C   . GLU B 1 27  ? 236.899 207.951 314.390 1.00 148.60 ? 27  GLU B C   1 
ATOM   6309  O  O   . GLU B 1 27  ? 237.323 207.532 313.307 1.00 148.60 ? 27  GLU B O   1 
ATOM   6310  C  CB  . GLU B 1 27  ? 238.497 208.554 316.229 1.00 148.60 ? 27  GLU B CB  1 
ATOM   6311  C  CG  . GLU B 1 27  ? 239.235 207.265 315.885 1.00 148.60 ? 27  GLU B CG  1 
ATOM   6312  C  CD  . GLU B 1 27  ? 240.489 207.498 315.061 1.00 148.60 ? 27  GLU B CD  1 
ATOM   6313  O  OE1 . GLU B 1 27  ? 240.726 208.647 314.634 1.00 148.60 ? 27  GLU B OE1 1 
ATOM   6314  O  OE2 . GLU B 1 27  ? 241.242 206.526 314.840 1.00 148.60 ? 27  GLU B OE2 1 
ATOM   6315  N  N   . GLN B 1 28  ? 235.820 207.435 314.973 1.00 145.09 ? 28  GLN B N   1 
ATOM   6316  C  CA  . GLN B 1 28  ? 235.165 206.253 314.424 1.00 145.09 ? 28  GLN B CA  1 
ATOM   6317  C  C   . GLN B 1 28  ? 234.160 206.577 313.324 1.00 145.09 ? 28  GLN B C   1 
ATOM   6318  O  O   . GLN B 1 28  ? 233.564 205.653 312.761 1.00 145.09 ? 28  GLN B O   1 
ATOM   6319  C  CB  . GLN B 1 28  ? 234.473 205.472 315.544 1.00 145.09 ? 28  GLN B CB  1 
ATOM   6320  C  CG  . GLN B 1 28  ? 235.428 204.840 316.543 1.00 145.09 ? 28  GLN B CG  1 
ATOM   6321  C  CD  . GLN B 1 28  ? 234.869 203.575 317.164 1.00 145.09 ? 28  GLN B CD  1 
ATOM   6322  O  OE1 . GLN B 1 28  ? 233.992 202.926 316.594 1.00 145.09 ? 28  GLN B OE1 1 
ATOM   6323  N  NE2 . GLN B 1 28  ? 235.374 203.218 318.339 1.00 145.09 ? 28  GLN B NE2 1 
ATOM   6324  N  N   . ASN B 1 29  ? 233.965 207.852 313.003 1.00 137.11 ? 29  ASN B N   1 
ATOM   6325  C  CA  . ASN B 1 29  ? 233.012 208.248 311.981 1.00 137.11 ? 29  ASN B CA  1 
ATOM   6326  C  C   . ASN B 1 29  ? 233.498 207.823 310.592 1.00 137.11 ? 29  ASN B C   1 
ATOM   6327  O  O   . ASN B 1 29  ? 234.651 207.433 310.394 1.00 137.11 ? 29  ASN B O   1 
ATOM   6328  C  CB  . ASN B 1 29  ? 232.798 209.760 312.028 1.00 137.11 ? 29  ASN B CB  1 
ATOM   6329  C  CG  . ASN B 1 29  ? 231.576 210.205 311.251 1.00 137.11 ? 29  ASN B CG  1 
ATOM   6330  O  OD1 . ASN B 1 29  ? 230.825 209.383 310.726 1.00 137.11 ? 29  ASN B OD1 1 
ATOM   6331  N  ND2 . ASN B 1 29  ? 231.381 211.514 311.160 1.00 137.11 ? 29  ASN B ND2 1 
ATOM   6332  N  N   . MET B 1 30  ? 232.586 207.895 309.622 1.00 126.58 ? 30  MET B N   1 
ATOM   6333  C  CA  . MET B 1 30  ? 232.898 207.655 308.219 1.00 126.58 ? 30  MET B CA  1 
ATOM   6334  C  C   . MET B 1 30  ? 233.191 208.935 307.449 1.00 126.58 ? 30  MET B C   1 
ATOM   6335  O  O   . MET B 1 30  ? 233.362 208.882 306.229 1.00 126.58 ? 30  MET B O   1 
ATOM   6336  C  CB  . MET B 1 30  ? 231.746 206.908 307.542 1.00 126.58 ? 30  MET B CB  1 
ATOM   6337  C  CG  . MET B 1 30  ? 230.405 207.623 307.612 1.00 126.58 ? 30  MET B CG  1 
ATOM   6338  S  SD  . MET B 1 30  ? 230.148 208.843 306.308 1.00 126.58 ? 30  MET B SD  1 
ATOM   6339  C  CE  . MET B 1 30  ? 230.090 207.784 304.869 1.00 126.58 ? 30  MET B CE  1 
ATOM   6340  N  N   . MET B 1 31  ? 233.243 210.077 308.125 1.00 134.29 ? 31  MET B N   1 
ATOM   6341  C  CA  . MET B 1 31  ? 233.425 211.375 307.493 1.00 134.29 ? 31  MET B CA  1 
ATOM   6342  C  C   . MET B 1 31  ? 234.783 211.943 307.881 1.00 134.29 ? 31  MET B C   1 
ATOM   6343  O  O   . MET B 1 31  ? 235.161 211.912 309.057 1.00 134.29 ? 31  MET B O   1 
ATOM   6344  C  CB  . MET B 1 31  ? 232.304 212.331 307.912 1.00 134.29 ? 31  MET B CB  1 
ATOM   6345  C  CG  . MET B 1 31  ? 232.159 213.574 307.057 1.00 134.29 ? 31  MET B CG  1 
ATOM   6346  S  SD  . MET B 1 31  ? 230.643 214.475 307.439 1.00 134.29 ? 31  MET B SD  1 
ATOM   6347  C  CE  . MET B 1 31  ? 230.669 215.745 306.176 1.00 134.29 ? 31  MET B CE  1 
ATOM   6348  N  N   . GLY B 1 32  ? 235.523 212.447 306.894 1.00 135.24 ? 32  GLY B N   1 
ATOM   6349  C  CA  . GLY B 1 32  ? 236.856 212.954 307.157 1.00 135.24 ? 32  GLY B CA  1 
ATOM   6350  C  C   . GLY B 1 32  ? 236.863 214.081 308.166 1.00 135.24 ? 32  GLY B C   1 
ATOM   6351  O  O   . GLY B 1 32  ? 236.071 215.013 308.048 1.00 135.24 ? 32  GLY B O   1 
ATOM   6352  N  N   . ALA B 1 33  ? 237.737 214.016 309.164 1.00 141.01 ? 33  ALA B N   1 
ATOM   6353  C  CA  . ALA B 1 33  ? 237.775 215.022 310.215 1.00 141.01 ? 33  ALA B CA  1 
ATOM   6354  C  C   . ALA B 1 33  ? 239.126 215.716 310.202 1.00 141.01 ? 33  ALA B C   1 
ATOM   6355  O  O   . ALA B 1 33  ? 240.167 215.057 310.286 1.00 141.01 ? 33  ALA B O   1 
ATOM   6356  C  CB  . ALA B 1 33  ? 237.509 214.400 311.588 1.00 141.01 ? 33  ALA B CB  1 
ATOM   6357  N  N   . VAL B 1 34  ? 239.107 217.043 310.094 1.00 145.59 ? 34  VAL B N   1 
ATOM   6358  C  CA  . VAL B 1 34  ? 240.333 217.829 310.113 1.00 145.59 ? 34  VAL B CA  1 
ATOM   6359  C  C   . VAL B 1 34  ? 240.173 218.949 311.129 1.00 145.59 ? 34  VAL B C   1 
ATOM   6360  O  O   . VAL B 1 34  ? 239.168 219.659 311.142 1.00 145.59 ? 34  VAL B O   1 
ATOM   6361  C  CB  . VAL B 1 34  ? 240.677 218.391 308.713 1.00 145.59 ? 34  VAL B CB  1 
ATOM   6362  C  CG1 . VAL B 1 34  ? 241.940 219.236 308.774 1.00 145.59 ? 34  VAL B CG1 1 
ATOM   6363  C  CG2 . VAL B 1 34  ? 240.840 217.259 307.713 1.00 145.59 ? 34  VAL B CG2 1 
ATOM   6364  N  N   . LEU B 1 35  ? 241.173 219.102 311.992 1.00 151.07 ? 35  LEU B N   1 
ATOM   6365  C  CA  . LEU B 1 35  ? 241.167 220.163 312.991 1.00 151.07 ? 35  LEU B CA  1 
ATOM   6366  C  C   . LEU B 1 35  ? 242.444 220.970 312.845 1.00 151.07 ? 35  LEU B C   1 
ATOM   6367  O  O   . LEU B 1 35  ? 243.543 220.417 312.950 1.00 151.07 ? 35  LEU B O   1 
ATOM   6368  C  CB  . LEU B 1 35  ? 241.049 219.593 314.407 1.00 151.07 ? 35  LEU B CB  1 
ATOM   6369  C  CG  . LEU B 1 35  ? 241.179 220.598 315.554 1.00 151.07 ? 35  LEU B CG  1 
ATOM   6370  C  CD1 . LEU B 1 35  ? 240.064 221.631 315.492 1.00 151.07 ? 35  LEU B CD1 1 
ATOM   6371  C  CD2 . LEU B 1 35  ? 241.181 219.885 316.898 1.00 151.07 ? 35  LEU B CD2 1 
ATOM   6372  N  N   . ILE B 1 36  ? 242.304 222.270 312.603 1.00 154.34 ? 36  ILE B N   1 
ATOM   6373  C  CA  . ILE B 1 36  ? 243.457 223.152 312.484 1.00 154.34 ? 36  ILE B CA  1 
ATOM   6374  C  C   . ILE B 1 36  ? 243.322 224.273 313.504 1.00 154.34 ? 36  ILE B C   1 
ATOM   6375  O  O   . ILE B 1 36  ? 242.215 224.658 313.896 1.00 154.34 ? 36  ILE B O   1 
ATOM   6376  C  CB  . ILE B 1 36  ? 243.630 223.725 311.059 1.00 154.34 ? 36  ILE B CB  1 
ATOM   6377  C  CG1 . ILE B 1 36  ? 242.516 224.717 310.733 1.00 154.34 ? 36  ILE B CG1 1 
ATOM   6378  C  CG2 . ILE B 1 36  ? 243.669 222.603 310.032 1.00 154.34 ? 36  ILE B CG2 1 
ATOM   6379  C  CD1 . ILE B 1 36  ? 242.784 225.545 309.496 1.00 154.34 ? 36  ILE B CD1 1 
ATOM   6380  N  N   . ASN B 1 37  ? 244.468 224.797 313.929 1.00 153.88 ? 37  ASN B N   1 
ATOM   6381  C  CA  . ASN B 1 37  ? 244.543 225.758 315.015 1.00 153.88 ? 37  ASN B CA  1 
ATOM   6382  C  C   . ASN B 1 37  ? 244.661 227.180 314.476 1.00 153.88 ? 37  ASN B C   1 
ATOM   6383  O  O   . ASN B 1 37  ? 244.597 227.430 313.270 1.00 153.88 ? 37  ASN B O   1 
ATOM   6384  C  CB  . ASN B 1 37  ? 245.723 225.423 315.932 1.00 153.88 ? 37  ASN B CB  1 
ATOM   6385  C  CG  . ASN B 1 37  ? 247.048 225.383 315.190 1.00 153.88 ? 37  ASN B CG  1 
ATOM   6386  O  OD1 . ASN B 1 37  ? 247.109 225.619 313.984 1.00 153.88 ? 37  ASN B OD1 1 
ATOM   6387  N  ND2 . ASN B 1 37  ? 248.118 225.078 315.912 1.00 153.88 ? 37  ASN B ND2 1 
ATOM   6388  N  N   . GLU B 1 38  ? 244.841 228.126 315.401 1.00 157.12 ? 38  GLU B N   1 
ATOM   6389  C  CA  . GLU B 1 38  ? 245.093 229.509 315.015 1.00 157.12 ? 38  GLU B CA  1 
ATOM   6390  C  C   . GLU B 1 38  ? 246.342 229.614 314.153 1.00 157.12 ? 38  GLU B C   1 
ATOM   6391  O  O   . GLU B 1 38  ? 246.425 230.465 313.260 1.00 157.12 ? 38  GLU B O   1 
ATOM   6392  C  CB  . GLU B 1 38  ? 245.225 230.380 316.266 1.00 157.12 ? 38  GLU B CB  1 
ATOM   6393  C  CG  . GLU B 1 38  ? 245.497 231.850 315.987 1.00 157.12 ? 38  GLU B CG  1 
ATOM   6394  C  CD  . GLU B 1 38  ? 244.271 232.586 315.487 1.00 157.12 ? 38  GLU B CD  1 
ATOM   6395  O  OE1 . GLU B 1 38  ? 243.158 232.279 315.962 1.00 157.12 ? 38  GLU B OE1 1 
ATOM   6396  O  OE2 . GLU B 1 38  ? 244.420 233.473 314.621 1.00 157.12 ? 38  GLU B OE2 1 
ATOM   6397  N  N   . ASN B 1 39  ? 247.320 228.745 314.396 1.00 156.43 ? 39  ASN B N   1 
ATOM   6398  C  CA  . ASN B 1 39  ? 248.543 228.697 313.611 1.00 156.43 ? 39  ASN B CA  1 
ATOM   6399  C  C   . ASN B 1 39  ? 248.391 227.864 312.345 1.00 156.43 ? 39  ASN B C   1 
ATOM   6400  O  O   . ASN B 1 39  ? 249.382 227.648 311.639 1.00 156.43 ? 39  ASN B O   1 
ATOM   6401  C  CB  . ASN B 1 39  ? 249.694 228.150 314.460 1.00 156.43 ? 39  ASN B CB  1 
ATOM   6402  C  CG  . ASN B 1 39  ? 251.046 228.678 314.021 1.00 156.43 ? 39  ASN B CG  1 
ATOM   6403  O  OD1 . ASN B 1 39  ? 251.204 229.870 313.759 1.00 156.43 ? 39  ASN B OD1 1 
ATOM   6404  N  ND2 . ASN B 1 39  ? 252.029 227.790 313.938 1.00 156.43 ? 39  ASN B ND2 1 
ATOM   6405  N  N   . ASP B 1 40  ? 247.182 227.380 312.057 1.00 154.78 ? 40  ASP B N   1 
ATOM   6406  C  CA  . ASP B 1 40  ? 246.846 226.594 310.872 1.00 154.78 ? 40  ASP B CA  1 
ATOM   6407  C  C   . ASP B 1 40  ? 247.521 225.229 310.858 1.00 154.78 ? 40  ASP B C   1 
ATOM   6408  O  O   . ASP B 1 40  ? 247.480 224.536 309.834 1.00 154.78 ? 40  ASP B O   1 
ATOM   6409  C  CB  . ASP B 1 40  ? 247.179 227.342 309.576 1.00 154.78 ? 40  ASP B CB  1 
ATOM   6410  C  CG  . ASP B 1 40  ? 246.425 228.650 309.450 1.00 154.78 ? 40  ASP B CG  1 
ATOM   6411  O  OD1 . ASP B 1 40  ? 245.304 228.745 309.992 1.00 154.78 ? 40  ASP B OD1 1 
ATOM   6412  O  OD2 . ASP B 1 40  ? 246.956 229.584 308.813 1.00 154.78 ? 40  ASP B OD2 1 
ATOM   6413  N  N   . GLU B 1 41  ? 248.146 224.824 311.957 1.00 152.04 ? 41  GLU B N   1 
ATOM   6414  C  CA  . GLU B 1 41  ? 248.687 223.478 312.048 1.00 152.04 ? 41  GLU B CA  1 
ATOM   6415  C  C   . GLU B 1 41  ? 247.553 222.475 312.203 1.00 152.04 ? 41  GLU B C   1 
ATOM   6416  O  O   . GLU B 1 41  ? 246.632 222.675 313.000 1.00 152.04 ? 41  GLU B O   1 
ATOM   6417  C  CB  . GLU B 1 41  ? 249.651 223.372 313.226 1.00 152.04 ? 41  GLU B CB  1 
ATOM   6418  C  CG  . GLU B 1 41  ? 250.682 224.484 313.281 1.00 152.04 ? 41  GLU B CG  1 
ATOM   6419  C  CD  . GLU B 1 41  ? 251.416 224.662 311.968 1.00 152.04 ? 41  GLU B CD  1 
ATOM   6420  O  OE1 . GLU B 1 41  ? 251.989 223.672 311.467 1.00 152.04 ? 41  GLU B OE1 1 
ATOM   6421  O  OE2 . GLU B 1 41  ? 251.427 225.793 311.438 1.00 152.04 ? 41  GLU B OE2 1 
ATOM   6422  N  N   . VAL B 1 42  ? 247.620 221.393 311.437 1.00 153.27 ? 42  VAL B N   1 
ATOM   6423  C  CA  . VAL B 1 42  ? 246.571 220.380 311.461 1.00 153.27 ? 42  VAL B CA  1 
ATOM   6424  C  C   . VAL B 1 42  ? 246.712 219.545 312.727 1.00 153.27 ? 42  VAL B C   1 
ATOM   6425  O  O   . VAL B 1 42  ? 247.801 219.055 313.046 1.00 153.27 ? 42  VAL B O   1 
ATOM   6426  C  CB  . VAL B 1 42  ? 246.635 219.498 310.205 1.00 153.27 ? 42  VAL B CB  1 
ATOM   6427  C  CG1 . VAL B 1 42  ? 245.494 218.491 310.209 1.00 153.27 ? 42  VAL B CG1 1 
ATOM   6428  C  CG2 . VAL B 1 42  ? 246.592 220.360 308.955 1.00 153.27 ? 42  VAL B CG2 1 
ATOM   6429  N  N   . MET B 1 43  ? 245.605 219.380 313.451 1.00 154.71 ? 43  MET B N   1 
ATOM   6430  C  CA  . MET B 1 43  ? 245.620 218.633 314.701 1.00 154.71 ? 43  MET B CA  1 
ATOM   6431  C  C   . MET B 1 43  ? 245.026 217.238 314.570 1.00 154.71 ? 43  MET B C   1 
ATOM   6432  O  O   . MET B 1 43  ? 245.322 216.371 315.400 1.00 154.71 ? 43  MET B O   1 
ATOM   6433  C  CB  . MET B 1 43  ? 244.865 219.407 315.787 1.00 154.71 ? 43  MET B CB  1 
ATOM   6434  C  CG  . MET B 1 43  ? 245.582 220.656 316.271 1.00 154.71 ? 43  MET B CG  1 
ATOM   6435  S  SD  . MET B 1 43  ? 247.120 220.282 317.134 1.00 154.71 ? 43  MET B SD  1 
ATOM   6436  C  CE  . MET B 1 43  ? 247.785 221.927 317.374 1.00 154.71 ? 43  MET B CE  1 
ATOM   6437  N  N   . PHE B 1 44  ? 244.194 216.995 313.559 1.00 148.61 ? 44  PHE B N   1 
ATOM   6438  C  CA  . PHE B 1 44  ? 243.557 215.698 313.398 1.00 148.61 ? 44  PHE B CA  1 
ATOM   6439  C  C   . PHE B 1 44  ? 243.396 215.372 311.922 1.00 148.61 ? 44  PHE B C   1 
ATOM   6440  O  O   . PHE B 1 44  ? 243.156 216.255 311.095 1.00 148.61 ? 44  PHE B O   1 
ATOM   6441  C  CB  . PHE B 1 44  ? 242.193 215.652 314.092 1.00 148.61 ? 44  PHE B CB  1 
ATOM   6442  C  CG  . PHE B 1 44  ? 241.586 214.283 314.137 1.00 148.61 ? 44  PHE B CG  1 
ATOM   6443  C  CD1 . PHE B 1 44  ? 242.333 213.196 314.559 1.00 148.61 ? 44  PHE B CD1 1 
ATOM   6444  C  CD2 . PHE B 1 44  ? 240.271 214.080 313.762 1.00 148.61 ? 44  PHE B CD2 1 
ATOM   6445  C  CE1 . PHE B 1 44  ? 241.779 211.931 314.602 1.00 148.61 ? 44  PHE B CE1 1 
ATOM   6446  C  CE2 . PHE B 1 44  ? 239.710 212.817 313.805 1.00 148.61 ? 44  PHE B CE2 1 
ATOM   6447  C  CZ  . PHE B 1 44  ? 240.465 211.742 314.225 1.00 148.61 ? 44  PHE B CZ  1 
ATOM   6448  N  N   . PHE B 1 45  ? 243.529 214.083 311.603 1.00 143.77 ? 45  PHE B N   1 
ATOM   6449  C  CA  . PHE B 1 45  ? 243.364 213.610 310.230 1.00 143.77 ? 45  PHE B CA  1 
ATOM   6450  C  C   . PHE B 1 45  ? 242.956 212.139 310.310 1.00 143.77 ? 45  PHE B C   1 
ATOM   6451  O  O   . PHE B 1 45  ? 243.812 211.269 310.493 1.00 143.77 ? 45  PHE B O   1 
ATOM   6452  C  CB  . PHE B 1 45  ? 244.646 213.797 309.434 1.00 143.77 ? 45  PHE B CB  1 
ATOM   6453  C  CG  . PHE B 1 45  ? 244.436 213.874 307.949 1.00 143.77 ? 45  PHE B CG  1 
ATOM   6454  C  CD1 . PHE B 1 45  ? 244.083 215.071 307.348 1.00 143.77 ? 45  PHE B CD1 1 
ATOM   6455  C  CD2 . PHE B 1 45  ? 244.604 212.754 307.153 1.00 143.77 ? 45  PHE B CD2 1 
ATOM   6456  C  CE1 . PHE B 1 45  ? 243.894 215.148 305.981 1.00 143.77 ? 45  PHE B CE1 1 
ATOM   6457  C  CE2 . PHE B 1 45  ? 244.417 212.825 305.786 1.00 143.77 ? 45  PHE B CE2 1 
ATOM   6458  C  CZ  . PHE B 1 45  ? 244.061 214.023 305.199 1.00 143.77 ? 45  PHE B CZ  1 
ATOM   6459  N  N   . ASN B 1 46  ? 241.663 211.876 310.164 1.00 135.55 ? 46  ASN B N   1 
ATOM   6460  C  CA  . ASN B 1 46  ? 241.128 210.537 310.357 1.00 135.55 ? 46  ASN B CA  1 
ATOM   6461  C  C   . ASN B 1 46  ? 241.403 209.671 309.135 1.00 135.55 ? 46  ASN B C   1 
ATOM   6462  O  O   . ASN B 1 46  ? 241.807 210.167 308.083 1.00 135.55 ? 46  ASN B O   1 
ATOM   6463  C  CB  . ASN B 1 46  ? 239.634 210.618 310.668 1.00 135.55 ? 46  ASN B CB  1 
ATOM   6464  C  CG  . ASN B 1 46  ? 238.793 211.006 309.467 1.00 135.55 ? 46  ASN B CG  1 
ATOM   6465  O  OD1 . ASN B 1 46  ? 239.308 211.358 308.407 1.00 135.55 ? 46  ASN B OD1 1 
ATOM   6466  N  ND2 . ASN B 1 46  ? 237.478 210.942 309.634 1.00 135.55 ? 46  ASN B ND2 1 
ATOM   6467  N  N   . PRO B 1 47  ? 241.217 208.353 309.252 1.00 135.04 ? 47  PRO B N   1 
ATOM   6468  C  CA  . PRO B 1 47  ? 241.343 207.498 308.062 1.00 135.04 ? 47  PRO B CA  1 
ATOM   6469  C  C   . PRO B 1 47  ? 240.385 207.867 306.943 1.00 135.04 ? 47  PRO B C   1 
ATOM   6470  O  O   . PRO B 1 47  ? 240.688 207.602 305.776 1.00 135.04 ? 47  PRO B O   1 
ATOM   6471  C  CB  . PRO B 1 47  ? 241.058 206.094 308.610 1.00 135.04 ? 47  PRO B CB  1 
ATOM   6472  C  CG  . PRO B 1 47  ? 241.459 206.169 310.038 1.00 135.04 ? 47  PRO B CG  1 
ATOM   6473  C  CD  . PRO B 1 47  ? 241.110 207.558 310.489 1.00 135.04 ? 47  PRO B CD  1 
ATOM   6474  N  N   . ALA B 1 48  ? 239.233 208.463 307.255 1.00 131.18 ? 48  ALA B N   1 
ATOM   6475  C  CA  . ALA B 1 48  ? 238.344 208.912 306.189 1.00 131.18 ? 48  ALA B CA  1 
ATOM   6476  C  C   . ALA B 1 48  ? 238.997 210.009 305.363 1.00 131.18 ? 48  ALA B C   1 
ATOM   6477  O  O   . ALA B 1 48  ? 239.000 209.952 304.127 1.00 131.18 ? 48  ALA B O   1 
ATOM   6478  C  CB  . ALA B 1 48  ? 237.018 209.394 306.773 1.00 131.18 ? 48  ALA B CB  1 
ATOM   6479  N  N   . ALA B 1 49  ? 239.568 211.015 306.028 1.00 137.37 ? 49  ALA B N   1 
ATOM   6480  C  CA  . ALA B 1 49  ? 240.319 212.035 305.305 1.00 137.37 ? 49  ALA B CA  1 
ATOM   6481  C  C   . ALA B 1 49  ? 241.530 211.425 304.616 1.00 137.37 ? 49  ALA B C   1 
ATOM   6482  O  O   . ALA B 1 49  ? 241.928 211.869 303.533 1.00 137.37 ? 49  ALA B O   1 
ATOM   6483  C  CB  . ALA B 1 49  ? 240.744 213.155 306.254 1.00 137.37 ? 49  ALA B CB  1 
ATOM   6484  N  N   . GLU B 1 50  ? 242.124 210.398 305.229 1.00 137.69 ? 50  GLU B N   1 
ATOM   6485  C  CA  . GLU B 1 50  ? 243.240 209.700 304.602 1.00 137.69 ? 50  GLU B CA  1 
ATOM   6486  C  C   . GLU B 1 50  ? 242.828 209.107 303.262 1.00 137.69 ? 50  GLU B C   1 
ATOM   6487  O  O   . GLU B 1 50  ? 243.528 209.262 302.259 1.00 137.69 ? 50  GLU B O   1 
ATOM   6488  C  CB  . GLU B 1 50  ? 243.760 208.604 305.531 1.00 137.69 ? 50  GLU B CB  1 
ATOM   6489  C  CG  . GLU B 1 50  ? 244.539 209.101 306.732 1.00 137.69 ? 50  GLU B CG  1 
ATOM   6490  C  CD  . GLU B 1 50  ? 245.248 207.975 307.457 1.00 137.69 ? 50  GLU B CD  1 
ATOM   6491  O  OE1 . GLU B 1 50  ? 244.622 206.914 307.666 1.00 137.69 ? 50  GLU B OE1 1 
ATOM   6492  O  OE2 . GLU B 1 50  ? 246.436 208.141 307.804 1.00 137.69 ? 50  GLU B OE2 1 
ATOM   6493  N  N   . LYS B 1 51  ? 241.684 208.426 303.228 1.00 129.86 ? 51  LYS B N   1 
ATOM   6494  C  CA  . LYS B 1 51  ? 241.254 207.794 301.990 1.00 129.86 ? 51  LYS B CA  1 
ATOM   6495  C  C   . LYS B 1 51  ? 240.760 208.824 300.986 1.00 129.86 ? 51  LYS B C   1 
ATOM   6496  O  O   . LYS B 1 51  ? 240.885 208.616 299.775 1.00 129.86 ? 51  LYS B O   1 
ATOM   6497  C  CB  . LYS B 1 51  ? 240.176 206.746 302.271 1.00 129.86 ? 51  LYS B CB  1 
ATOM   6498  C  CG  . LYS B 1 51  ? 238.819 207.304 302.649 1.00 129.86 ? 51  LYS B CG  1 
ATOM   6499  C  CD  . LYS B 1 51  ? 237.816 206.193 302.907 1.00 129.86 ? 51  LYS B CD  1 
ATOM   6500  C  CE  . LYS B 1 51  ? 237.435 205.483 301.618 1.00 129.86 ? 51  LYS B CE  1 
ATOM   6501  N  NZ  . LYS B 1 51  ? 236.696 206.380 300.687 1.00 129.86 ? 51  LYS B NZ  1 
ATOM   6502  N  N   . LEU B 1 52  ? 240.209 209.939 301.464 1.00 131.05 ? 52  LEU B N   1 
ATOM   6503  C  CA  . LEU B 1 52  ? 239.772 210.987 300.551 1.00 131.05 ? 52  LEU B CA  1 
ATOM   6504  C  C   . LEU B 1 52  ? 240.962 211.645 299.861 1.00 131.05 ? 52  LEU B C   1 
ATOM   6505  O  O   . LEU B 1 52  ? 240.989 211.784 298.633 1.00 131.05 ? 52  LEU B O   1 
ATOM   6506  C  CB  . LEU B 1 52  ? 238.941 212.024 301.308 1.00 131.05 ? 52  LEU B CB  1 
ATOM   6507  C  CG  . LEU B 1 52  ? 237.512 211.611 301.667 1.00 131.05 ? 52  LEU B CG  1 
ATOM   6508  C  CD1 . LEU B 1 52  ? 236.855 212.659 302.551 1.00 131.05 ? 52  LEU B CD1 1 
ATOM   6509  C  CD2 . LEU B 1 52  ? 236.691 211.372 300.409 1.00 131.05 ? 52  LEU B CD2 1 
ATOM   6510  N  N   . TRP B 1 53  ? 241.969 212.049 300.641 1.00 137.37 ? 53  TRP B N   1 
ATOM   6511  C  CA  . TRP B 1 53  ? 243.091 212.807 300.101 1.00 137.37 ? 53  TRP B CA  1 
ATOM   6512  C  C   . TRP B 1 53  ? 244.224 211.930 299.591 1.00 137.37 ? 53  TRP B C   1 
ATOM   6513  O  O   . TRP B 1 53  ? 245.157 212.452 298.973 1.00 137.37 ? 53  TRP B O   1 
ATOM   6514  C  CB  . TRP B 1 53  ? 243.647 213.758 301.163 1.00 137.37 ? 53  TRP B CB  1 
ATOM   6515  C  CG  . TRP B 1 53  ? 243.020 215.115 301.165 1.00 137.37 ? 53  TRP B CG  1 
ATOM   6516  C  CD1 . TRP B 1 53  ? 243.330 216.162 300.348 1.00 137.37 ? 53  TRP B CD1 1 
ATOM   6517  C  CD2 . TRP B 1 53  ? 241.989 215.583 302.043 1.00 137.37 ? 53  TRP B CD2 1 
ATOM   6518  N  NE1 . TRP B 1 53  ? 242.549 217.249 300.653 1.00 137.37 ? 53  TRP B NE1 1 
ATOM   6519  C  CE2 . TRP B 1 53  ? 241.718 216.920 301.692 1.00 137.37 ? 53  TRP B CE2 1 
ATOM   6520  C  CE3 . TRP B 1 53  ? 241.266 215.000 303.088 1.00 137.37 ? 53  TRP B CE3 1 
ATOM   6521  C  CZ2 . TRP B 1 53  ? 240.755 217.684 302.347 1.00 137.37 ? 53  TRP B CZ2 1 
ATOM   6522  C  CZ3 . TRP B 1 53  ? 240.310 215.760 303.738 1.00 137.37 ? 53  TRP B CZ3 1 
ATOM   6523  C  CH2 . TRP B 1 53  ? 240.063 217.087 303.365 1.00 137.37 ? 53  TRP B CH2 1 
ATOM   6524  N  N   . GLY B 1 54  ? 244.180 210.625 299.838 1.00 136.50 ? 54  GLY B N   1 
ATOM   6525  C  CA  . GLY B 1 54  ? 245.282 209.760 299.488 1.00 136.50 ? 54  GLY B CA  1 
ATOM   6526  C  C   . GLY B 1 54  ? 246.506 209.899 300.369 1.00 136.50 ? 54  GLY B C   1 
ATOM   6527  O  O   . GLY B 1 54  ? 247.559 209.346 300.027 1.00 136.50 ? 54  GLY B O   1 
ATOM   6528  N  N   . TYR B 1 55  ? 246.404 210.612 301.486 1.00 136.43 ? 55  TYR B N   1 
ATOM   6529  C  CA  . TYR B 1 55  ? 247.553 210.915 302.327 1.00 136.43 ? 55  TYR B CA  1 
ATOM   6530  C  C   . TYR B 1 55  ? 247.541 210.084 303.605 1.00 136.43 ? 55  TYR B C   1 
ATOM   6531  O  O   . TYR B 1 55  ? 246.526 209.502 303.993 1.00 136.43 ? 55  TYR B O   1 
ATOM   6532  C  CB  . TYR B 1 55  ? 247.578 212.401 302.685 1.00 136.43 ? 55  TYR B CB  1 
ATOM   6533  C  CG  . TYR B 1 55  ? 248.074 213.304 301.581 1.00 136.43 ? 55  TYR B CG  1 
ATOM   6534  C  CD1 . TYR B 1 55  ? 249.378 213.209 301.113 1.00 136.43 ? 55  TYR B CD1 1 
ATOM   6535  C  CD2 . TYR B 1 55  ? 247.240 214.256 301.009 1.00 136.43 ? 55  TYR B CD2 1 
ATOM   6536  C  CE1 . TYR B 1 55  ? 249.837 214.036 300.105 1.00 136.43 ? 55  TYR B CE1 1 
ATOM   6537  C  CE2 . TYR B 1 55  ? 247.689 215.087 300.000 1.00 136.43 ? 55  TYR B CE2 1 
ATOM   6538  C  CZ  . TYR B 1 55  ? 248.989 214.972 299.552 1.00 136.43 ? 55  TYR B CZ  1 
ATOM   6539  O  OH  . TYR B 1 55  ? 249.442 215.797 298.547 1.00 136.43 ? 55  TYR B OH  1 
ATOM   6540  N  N   . LYS B 1 56  ? 248.699 210.038 304.258 1.00 138.30 ? 56  LYS B N   1 
ATOM   6541  C  CA  . LYS B 1 56  ? 248.838 209.425 305.570 1.00 138.30 ? 56  LYS B CA  1 
ATOM   6542  C  C   . LYS B 1 56  ? 248.687 210.483 306.654 1.00 138.30 ? 56  LYS B C   1 
ATOM   6543  O  O   . LYS B 1 56  ? 249.030 211.652 306.460 1.00 138.30 ? 56  LYS B O   1 
ATOM   6544  C  CB  . LYS B 1 56  ? 250.193 208.729 305.707 1.00 138.30 ? 56  LYS B CB  1 
ATOM   6545  C  CG  . LYS B 1 56  ? 250.398 207.570 304.748 1.00 138.30 ? 56  LYS B CG  1 
ATOM   6546  C  CD  . LYS B 1 56  ? 249.328 206.509 304.930 1.00 138.30 ? 56  LYS B CD  1 
ATOM   6547  C  CE  . LYS B 1 56  ? 249.643 205.263 304.121 1.00 138.30 ? 56  LYS B CE  1 
ATOM   6548  N  NZ  . LYS B 1 56  ? 248.588 204.223 304.272 1.00 138.30 ? 56  LYS B NZ  1 
ATOM   6549  N  N   . ARG B 1 57  ? 248.169 210.057 307.809 1.00 144.31 ? 57  ARG B N   1 
ATOM   6550  C  CA  . ARG B 1 57  ? 247.903 211.003 308.889 1.00 144.31 ? 57  ARG B CA  1 
ATOM   6551  C  C   . ARG B 1 57  ? 249.195 211.565 309.471 1.00 144.31 ? 57  ARG B C   1 
ATOM   6552  O  O   . ARG B 1 57  ? 249.220 212.701 309.957 1.00 144.31 ? 57  ARG B O   1 
ATOM   6553  C  CB  . ARG B 1 57  ? 247.059 210.339 309.979 1.00 144.31 ? 57  ARG B CB  1 
ATOM   6554  C  CG  . ARG B 1 57  ? 247.813 209.354 310.860 1.00 144.31 ? 57  ARG B CG  1 
ATOM   6555  C  CD  . ARG B 1 57  ? 246.967 208.909 312.042 1.00 144.31 ? 57  ARG B CD  1 
ATOM   6556  N  NE  . ARG B 1 57  ? 246.066 207.818 311.691 1.00 144.31 ? 57  ARG B NE  1 
ATOM   6557  C  CZ  . ARG B 1 57  ? 246.409 206.537 311.681 1.00 144.31 ? 57  ARG B CZ  1 
ATOM   6558  N  NH1 . ARG B 1 57  ? 247.633 206.146 311.999 1.00 144.31 ? 57  ARG B NH1 1 
ATOM   6559  N  NH2 . ARG B 1 57  ? 245.502 205.624 311.344 1.00 144.31 ? 57  ARG B NH2 1 
ATOM   6560  N  N   . GLU B 1 58  ? 250.277 210.782 309.441 1.00 145.61 ? 58  GLU B N   1 
ATOM   6561  C  CA  . GLU B 1 58  ? 251.542 211.257 309.992 1.00 145.61 ? 58  GLU B CA  1 
ATOM   6562  C  C   . GLU B 1 58  ? 252.113 212.404 309.171 1.00 145.61 ? 58  GLU B C   1 
ATOM   6563  O  O   . GLU B 1 58  ? 252.799 213.277 309.716 1.00 145.61 ? 58  GLU B O   1 
ATOM   6564  C  CB  . GLU B 1 58  ? 252.546 210.107 310.071 1.00 145.61 ? 58  GLU B CB  1 
ATOM   6565  C  CG  . GLU B 1 58  ? 252.316 209.156 311.236 1.00 145.61 ? 58  GLU B CG  1 
ATOM   6566  C  CD  . GLU B 1 58  ? 251.180 208.183 310.982 1.00 145.61 ? 58  GLU B CD  1 
ATOM   6567  O  OE1 . GLU B 1 58  ? 250.851 207.947 309.801 1.00 145.61 ? 58  GLU B OE1 1 
ATOM   6568  O  OE2 . GLU B 1 58  ? 250.618 207.655 311.965 1.00 145.61 ? 58  GLU B OE2 1 
ATOM   6569  N  N   . GLU B 1 59  ? 251.841 212.423 307.865 1.00 142.84 ? 59  GLU B N   1 
ATOM   6570  C  CA  . GLU B 1 59  ? 252.335 213.504 307.021 1.00 142.84 ? 59  GLU B CA  1 
ATOM   6571  C  C   . GLU B 1 59  ? 251.688 214.833 307.378 1.00 142.84 ? 59  GLU B C   1 
ATOM   6572  O  O   . GLU B 1 59  ? 252.249 215.895 307.090 1.00 142.84 ? 59  GLU B O   1 
ATOM   6573  C  CB  . GLU B 1 59  ? 252.075 213.183 305.550 1.00 142.84 ? 59  GLU B CB  1 
ATOM   6574  C  CG  . GLU B 1 59  ? 252.289 211.730 305.174 1.00 142.84 ? 59  GLU B CG  1 
ATOM   6575  C  CD  . GLU B 1 59  ? 251.943 211.455 303.725 1.00 142.84 ? 59  GLU B CD  1 
ATOM   6576  O  OE1 . GLU B 1 59  ? 252.849 211.535 302.870 1.00 142.84 ? 59  GLU B OE1 1 
ATOM   6577  O  OE2 . GLU B 1 59  ? 250.761 211.167 303.440 1.00 142.84 ? 59  GLU B OE2 1 
ATOM   6578  N  N   . VAL B 1 60  ? 250.514 214.797 308.005 1.00 147.61 ? 60  VAL B N   1 
ATOM   6579  C  CA  . VAL B 1 60  ? 249.723 215.995 308.214 1.00 147.61 ? 60  VAL B CA  1 
ATOM   6580  C  C   . VAL B 1 60  ? 249.641 216.398 309.684 1.00 147.61 ? 60  VAL B C   1 
ATOM   6581  O  O   . VAL B 1 60  ? 249.464 217.586 309.977 1.00 147.61 ? 60  VAL B O   1 
ATOM   6582  C  CB  . VAL B 1 60  ? 248.311 215.809 307.617 1.00 147.61 ? 60  VAL B CB  1 
ATOM   6583  C  CG1 . VAL B 1 60  ? 247.570 217.131 307.552 1.00 147.61 ? 60  VAL B CG1 1 
ATOM   6584  C  CG2 . VAL B 1 60  ? 248.397 215.174 306.237 1.00 147.61 ? 60  VAL B CG2 1 
ATOM   6585  N  N   . ILE B 1 61  ? 249.778 215.453 310.615 1.00 149.14 ? 61  ILE B N   1 
ATOM   6586  C  CA  . ILE B 1 61  ? 249.671 215.780 312.033 1.00 149.14 ? 61  ILE B CA  1 
ATOM   6587  C  C   . ILE B 1 61  ? 250.850 216.652 312.436 1.00 149.14 ? 61  ILE B C   1 
ATOM   6588  O  O   . ILE B 1 61  ? 252.013 216.301 312.201 1.00 149.14 ? 61  ILE B O   1 
ATOM   6589  C  CB  . ILE B 1 61  ? 249.601 214.505 312.879 1.00 149.14 ? 61  ILE B CB  1 
ATOM   6590  C  CG1 . ILE B 1 61  ? 248.241 213.825 312.707 1.00 149.14 ? 61  ILE B CG1 1 
ATOM   6591  C  CG2 . ILE B 1 61  ? 249.862 214.819 314.345 1.00 149.14 ? 61  ILE B CG2 1 
ATOM   6592  C  CD1 . ILE B 1 61  ? 247.096 214.585 313.331 1.00 149.14 ? 61  ILE B CD1 1 
ATOM   6593  N  N   . GLY B 1 62  ? 250.554 217.798 313.045 1.00 152.21 ? 62  GLY B N   1 
ATOM   6594  C  CA  . GLY B 1 62  ? 251.585 218.713 313.489 1.00 152.21 ? 62  GLY B CA  1 
ATOM   6595  C  C   . GLY B 1 62  ? 252.245 219.519 312.396 1.00 152.21 ? 62  GLY B C   1 
ATOM   6596  O  O   . GLY B 1 62  ? 253.257 220.178 312.661 1.00 152.21 ? 62  GLY B O   1 
ATOM   6597  N  N   . ASN B 1 63  ? 251.711 219.492 311.180 1.00 150.67 ? 63  ASN B N   1 
ATOM   6598  C  CA  . ASN B 1 63  ? 252.312 220.166 310.040 1.00 150.67 ? 63  ASN B CA  1 
ATOM   6599  C  C   . ASN B 1 63  ? 251.392 221.265 309.523 1.00 150.67 ? 63  ASN B C   1 
ATOM   6600  O  O   . ASN B 1 63  ? 250.250 221.421 309.965 1.00 150.67 ? 63  ASN B O   1 
ATOM   6601  C  CB  . ASN B 1 63  ? 252.635 219.160 308.932 1.00 150.67 ? 63  ASN B CB  1 
ATOM   6602  C  CG  . ASN B 1 63  ? 253.576 218.067 309.399 1.00 150.67 ? 63  ASN B CG  1 
ATOM   6603  O  OD1 . ASN B 1 63  ? 254.427 218.293 310.259 1.00 150.67 ? 63  ASN B OD1 1 
ATOM   6604  N  ND2 . ASN B 1 63  ? 253.424 216.875 308.840 1.00 150.67 ? 63  ASN B ND2 1 
ATOM   6605  N  N   . ASN B 1 64  ? 251.914 222.035 308.572 1.00 150.02 ? 64  ASN B N   1 
ATOM   6606  C  CA  . ASN B 1 64  ? 251.197 223.190 308.055 1.00 150.02 ? 64  ASN B CA  1 
ATOM   6607  C  C   . ASN B 1 64  ? 250.042 222.761 307.156 1.00 150.02 ? 64  ASN B C   1 
ATOM   6608  O  O   . ASN B 1 64  ? 250.037 221.668 306.587 1.00 150.02 ? 64  ASN B O   1 
ATOM   6609  C  CB  . ASN B 1 64  ? 252.147 224.104 307.282 1.00 150.02 ? 64  ASN B CB  1 
ATOM   6610  C  CG  . ASN B 1 64  ? 251.552 225.473 307.015 1.00 150.02 ? 64  ASN B CG  1 
ATOM   6611  O  OD1 . ASN B 1 64  ? 250.464 225.794 307.493 1.00 150.02 ? 64  ASN B OD1 1 
ATOM   6612  N  ND2 . ASN B 1 64  ? 252.265 226.289 306.247 1.00 150.02 ? 64  ASN B ND2 1 
ATOM   6613  N  N   . ILE B 1 65  ? 249.055 223.650 307.031 1.00 147.64 ? 65  ILE B N   1 
ATOM   6614  C  CA  . ILE B 1 65  ? 247.903 223.412 306.176 1.00 147.64 ? 65  ILE B CA  1 
ATOM   6615  C  C   . ILE B 1 65  ? 248.260 223.465 304.699 1.00 147.64 ? 65  ILE B C   1 
ATOM   6616  O  O   . ILE B 1 65  ? 247.397 223.227 303.849 1.00 147.64 ? 65  ILE B O   1 
ATOM   6617  C  CB  . ILE B 1 65  ? 246.797 224.440 306.504 1.00 147.64 ? 65  ILE B CB  1 
ATOM   6618  C  CG1 . ILE B 1 65  ? 245.426 223.952 306.027 1.00 147.64 ? 65  ILE B CG1 1 
ATOM   6619  C  CG2 . ILE B 1 65  ? 247.133 225.790 305.890 1.00 147.64 ? 65  ILE B CG2 1 
ATOM   6620  C  CD1 . ILE B 1 65  ? 245.056 222.579 306.525 1.00 147.64 ? 65  ILE B CD1 1 
ATOM   6621  N  N   . ASP B 1 66  ? 249.520 223.755 304.374 1.00 147.91 ? 66  ASP B N   1 
ATOM   6622  C  CA  . ASP B 1 66  ? 249.901 223.999 302.987 1.00 147.91 ? 66  ASP B CA  1 
ATOM   6623  C  C   . ASP B 1 66  ? 249.678 222.768 302.115 1.00 147.91 ? 66  ASP B C   1 
ATOM   6624  O  O   . ASP B 1 66  ? 249.069 222.859 301.042 1.00 147.91 ? 66  ASP B O   1 
ATOM   6625  C  CB  . ASP B 1 66  ? 251.361 224.446 302.926 1.00 147.91 ? 66  ASP B CB  1 
ATOM   6626  C  CG  . ASP B 1 66  ? 252.280 223.539 303.719 1.00 147.91 ? 66  ASP B CG  1 
ATOM   6627  O  OD1 . ASP B 1 66  ? 251.766 222.636 304.413 1.00 147.91 ? 66  ASP B OD1 1 
ATOM   6628  O  OD2 . ASP B 1 66  ? 253.512 223.729 303.652 1.00 147.91 ? 66  ASP B OD2 1 
ATOM   6629  N  N   . MET B 1 67  ? 250.155 221.604 302.559 1.00 146.93 ? 67  MET B N   1 
ATOM   6630  C  CA  . MET B 1 67  ? 250.117 220.430 301.694 1.00 146.93 ? 67  MET B CA  1 
ATOM   6631  C  C   . MET B 1 67  ? 248.700 219.924 301.465 1.00 146.93 ? 67  MET B C   1 
ATOM   6632  O  O   . MET B 1 67  ? 248.460 219.219 300.479 1.00 146.93 ? 67  MET B O   1 
ATOM   6633  C  CB  . MET B 1 67  ? 250.987 219.310 302.268 1.00 146.93 ? 67  MET B CB  1 
ATOM   6634  C  CG  . MET B 1 67  ? 250.271 218.384 303.234 1.00 146.93 ? 67  MET B CG  1 
ATOM   6635  S  SD  . MET B 1 67  ? 250.037 219.129 304.853 1.00 146.93 ? 67  MET B SD  1 
ATOM   6636  C  CE  . MET B 1 67  ? 251.729 219.179 305.433 1.00 146.93 ? 67  MET B CE  1 
ATOM   6637  N  N   . LEU B 1 68  ? 247.758 220.264 302.344 1.00 148.55 ? 68  LEU B N   1 
ATOM   6638  C  CA  . LEU B 1 68  ? 246.373 219.862 302.134 1.00 148.55 ? 68  LEU B CA  1 
ATOM   6639  C  C   . LEU B 1 68  ? 245.681 220.686 301.058 1.00 148.55 ? 68  LEU B C   1 
ATOM   6640  O  O   . LEU B 1 68  ? 244.569 220.333 300.652 1.00 148.55 ? 68  LEU B O   1 
ATOM   6641  C  CB  . LEU B 1 68  ? 245.590 219.960 303.444 1.00 148.55 ? 68  LEU B CB  1 
ATOM   6642  C  CG  . LEU B 1 68  ? 245.979 218.968 304.542 1.00 148.55 ? 68  LEU B CG  1 
ATOM   6643  C  CD1 . LEU B 1 68  ? 244.959 218.991 305.670 1.00 148.55 ? 68  LEU B CD1 1 
ATOM   6644  C  CD2 . LEU B 1 68  ? 246.123 217.564 303.975 1.00 148.55 ? 68  LEU B CD2 1 
ATOM   6645  N  N   . ILE B 1 69  ? 246.304 221.764 300.593 1.00 149.98 ? 69  ILE B N   1 
ATOM   6646  C  CA  . ILE B 1 69  ? 245.729 222.613 299.554 1.00 149.98 ? 69  ILE B CA  1 
ATOM   6647  C  C   . ILE B 1 69  ? 246.194 222.113 298.192 1.00 149.98 ? 69  ILE B C   1 
ATOM   6648  O  O   . ILE B 1 69  ? 247.356 221.704 298.050 1.00 149.98 ? 69  ILE B O   1 
ATOM   6649  C  CB  . ILE B 1 69  ? 246.117 224.086 299.760 1.00 149.98 ? 69  ILE B CB  1 
ATOM   6650  C  CG1 . ILE B 1 69  ? 246.039 224.463 301.241 1.00 149.98 ? 69  ILE B CG1 1 
ATOM   6651  C  CG2 . ILE B 1 69  ? 245.223 224.994 298.936 1.00 149.98 ? 69  ILE B CG2 1 
ATOM   6652  C  CD1 . ILE B 1 69  ? 244.652 224.349 301.833 1.00 149.98 ? 69  ILE B CD1 1 
ATOM   6653  N  N   . PRO B 1 70  ? 245.334 222.113 297.173 1.00 150.74 ? 70  PRO B N   1 
ATOM   6654  C  CA  . PRO B 1 70  ? 245.800 221.784 295.822 1.00 150.74 ? 70  PRO B CA  1 
ATOM   6655  C  C   . PRO B 1 70  ? 246.846 222.782 295.345 1.00 150.74 ? 70  PRO B C   1 
ATOM   6656  O  O   . PRO B 1 70  ? 246.849 223.948 295.746 1.00 150.74 ? 70  PRO B O   1 
ATOM   6657  C  CB  . PRO B 1 70  ? 244.523 221.856 294.978 1.00 150.74 ? 70  PRO B CB  1 
ATOM   6658  C  CG  . PRO B 1 70  ? 243.419 221.616 295.946 1.00 150.74 ? 70  PRO B CG  1 
ATOM   6659  C  CD  . PRO B 1 70  ? 243.868 222.232 297.238 1.00 150.74 ? 70  PRO B CD  1 
ATOM   6660  N  N   . ARG B 1 71  ? 247.742 222.304 294.480 1.00 150.11 ? 71  ARG B N   1 
ATOM   6661  C  CA  . ARG B 1 71  ? 248.865 223.121 294.034 1.00 150.11 ? 71  ARG B CA  1 
ATOM   6662  C  C   . ARG B 1 71  ? 248.386 224.385 293.332 1.00 150.11 ? 71  ARG B C   1 
ATOM   6663  O  O   . ARG B 1 71  ? 248.915 225.478 293.563 1.00 150.11 ? 71  ARG B O   1 
ATOM   6664  C  CB  . ARG B 1 71  ? 249.765 222.300 293.111 1.00 150.11 ? 71  ARG B CB  1 
ATOM   6665  C  CG  . ARG B 1 71  ? 250.355 221.064 293.770 1.00 150.11 ? 71  ARG B CG  1 
ATOM   6666  C  CD  . ARG B 1 71  ? 251.321 220.344 292.844 1.00 150.11 ? 71  ARG B CD  1 
ATOM   6667  N  NE  . ARG B 1 71  ? 251.852 219.130 293.451 1.00 150.11 ? 71  ARG B NE  1 
ATOM   6668  C  CZ  . ARG B 1 71  ? 252.638 218.262 292.828 1.00 150.11 ? 71  ARG B CZ  1 
ATOM   6669  N  NH1 . ARG B 1 71  ? 253.008 218.444 291.571 1.00 150.11 ? 71  ARG B NH1 1 
ATOM   6670  N  NH2 . ARG B 1 71  ? 253.063 217.186 293.483 1.00 150.11 ? 71  ARG B NH2 1 
ATOM   6671  N  N   . ASP B 1 72  ? 247.373 224.255 292.473 1.00 149.91 ? 72  ASP B N   1 
ATOM   6672  C  CA  . ASP B 1 72  ? 246.864 225.411 291.745 1.00 149.91 ? 72  ASP B CA  1 
ATOM   6673  C  C   . ASP B 1 72  ? 246.227 226.442 292.666 1.00 149.91 ? 72  ASP B C   1 
ATOM   6674  O  O   . ASP B 1 72  ? 246.112 227.611 292.283 1.00 149.91 ? 72  ASP B O   1 
ATOM   6675  C  CB  . ASP B 1 72  ? 245.856 224.961 290.685 1.00 149.91 ? 72  ASP B CB  1 
ATOM   6676  C  CG  . ASP B 1 72  ? 244.842 223.969 291.224 1.00 149.91 ? 72  ASP B CG  1 
ATOM   6677  O  OD1 . ASP B 1 72  ? 244.648 223.918 292.457 1.00 149.91 ? 72  ASP B OD1 1 
ATOM   6678  O  OD2 . ASP B 1 72  ? 244.239 223.237 290.412 1.00 149.91 ? 72  ASP B OD2 1 
ATOM   6679  N  N   . LEU B 1 73  ? 245.813 226.041 293.867 1.00 149.39 ? 73  LEU B N   1 
ATOM   6680  C  CA  . LEU B 1 73  ? 245.199 226.951 294.820 1.00 149.39 ? 73  LEU B CA  1 
ATOM   6681  C  C   . LEU B 1 73  ? 246.082 227.233 296.026 1.00 149.39 ? 73  LEU B C   1 
ATOM   6682  O  O   . LEU B 1 73  ? 245.780 228.157 296.791 1.00 149.39 ? 73  LEU B O   1 
ATOM   6683  C  CB  . LEU B 1 73  ? 243.848 226.388 295.289 1.00 149.39 ? 73  LEU B CB  1 
ATOM   6684  C  CG  . LEU B 1 73  ? 242.875 227.332 295.999 1.00 149.39 ? 73  LEU B CG  1 
ATOM   6685  C  CD1 . LEU B 1 73  ? 242.489 228.485 295.087 1.00 149.39 ? 73  LEU B CD1 1 
ATOM   6686  C  CD2 . LEU B 1 73  ? 241.641 226.575 296.465 1.00 149.39 ? 73  LEU B CD2 1 
ATOM   6687  N  N   . ARG B 1 74  ? 247.174 226.487 296.193 1.00 148.99 ? 74  ARG B N   1 
ATOM   6688  C  CA  . ARG B 1 74  ? 248.050 226.640 297.355 1.00 148.99 ? 74  ARG B CA  1 
ATOM   6689  C  C   . ARG B 1 74  ? 248.552 228.064 297.569 1.00 148.99 ? 74  ARG B C   1 
ATOM   6690  O  O   . ARG B 1 74  ? 248.578 228.511 298.725 1.00 148.99 ? 74  ARG B O   1 
ATOM   6691  C  CB  . ARG B 1 74  ? 249.222 225.655 297.233 1.00 148.99 ? 74  ARG B CB  1 
ATOM   6692  C  CG  . ARG B 1 74  ? 250.081 225.554 298.483 1.00 148.99 ? 74  ARG B CG  1 
ATOM   6693  C  CD  . ARG B 1 74  ? 250.716 224.177 298.614 1.00 148.99 ? 74  ARG B CD  1 
ATOM   6694  N  NE  . ARG B 1 74  ? 251.625 223.880 297.513 1.00 148.99 ? 74  ARG B NE  1 
ATOM   6695  C  CZ  . ARG B 1 74  ? 251.602 222.758 296.805 1.00 148.99 ? 74  ARG B CZ  1 
ATOM   6696  N  NH1 . ARG B 1 74  ? 250.724 221.801 297.055 1.00 148.99 ? 74  ARG B NH1 1 
ATOM   6697  N  NH2 . ARG B 1 74  ? 252.484 222.593 295.823 1.00 148.99 ? 74  ARG B NH2 1 
ATOM   6698  N  N   . PRO B 1 75  ? 248.980 228.814 296.547 1.00 149.78 ? 75  PRO B N   1 
ATOM   6699  C  CA  . PRO B 1 75  ? 249.380 230.207 296.810 1.00 149.78 ? 75  PRO B CA  1 
ATOM   6700  C  C   . PRO B 1 75  ? 248.239 231.098 297.275 1.00 149.78 ? 75  PRO B C   1 
ATOM   6701  O  O   . PRO B 1 75  ? 248.497 232.165 297.847 1.00 149.78 ? 75  PRO B O   1 
ATOM   6702  C  CB  . PRO B 1 75  ? 249.942 230.673 295.459 1.00 149.78 ? 75  PRO B CB  1 
ATOM   6703  C  CG  . PRO B 1 75  ? 250.319 229.423 294.750 1.00 149.78 ? 75  PRO B CG  1 
ATOM   6704  C  CD  . PRO B 1 75  ? 249.293 228.419 295.162 1.00 149.78 ? 75  PRO B CD  1 
ATOM   6705  N  N   . ALA B 1 76  ? 246.985 230.700 297.052 1.00 149.57 ? 76  ALA B N   1 
ATOM   6706  C  CA  . ALA B 1 76  ? 245.856 231.589 297.296 1.00 149.57 ? 76  ALA B CA  1 
ATOM   6707  C  C   . ALA B 1 76  ? 245.065 231.258 298.554 1.00 149.57 ? 76  ALA B C   1 
ATOM   6708  O  O   . ALA B 1 76  ? 244.579 232.182 299.217 1.00 149.57 ? 76  ALA B O   1 
ATOM   6709  C  CB  . ALA B 1 76  ? 244.908 231.573 296.094 1.00 149.57 ? 76  ALA B CB  1 
ATOM   6710  N  N   . HIS B 1 77  ? 244.909 229.979 298.892 1.00 151.04 ? 77  HIS B N   1 
ATOM   6711  C  CA  . HIS B 1 77  ? 244.043 229.589 300.004 1.00 151.04 ? 77  HIS B CA  1 
ATOM   6712  C  C   . HIS B 1 77  ? 244.483 230.154 301.356 1.00 151.04 ? 77  HIS B C   1 
ATOM   6713  O  O   . HIS B 1 77  ? 243.620 230.586 302.126 1.00 151.04 ? 77  HIS B O   1 
ATOM   6714  C  CB  . HIS B 1 77  ? 243.921 228.066 300.096 1.00 151.04 ? 77  HIS B CB  1 
ATOM   6715  C  CG  . HIS B 1 77  ? 242.586 227.598 300.596 1.00 151.04 ? 77  HIS B CG  1 
ATOM   6716  N  ND1 . HIS B 1 77  ? 242.257 227.575 301.935 1.00 151.04 ? 77  HIS B ND1 1 
ATOM   6717  C  CD2 . HIS B 1 77  ? 241.497 227.138 299.935 1.00 151.04 ? 77  HIS B CD2 1 
ATOM   6718  C  CE1 . HIS B 1 77  ? 241.024 227.122 302.077 1.00 151.04 ? 77  HIS B CE1 1 
ATOM   6719  N  NE2 . HIS B 1 77  ? 240.540 226.848 300.879 1.00 151.04 ? 77  HIS B NE2 1 
ATOM   6720  N  N   . PRO B 1 78  ? 245.776 230.150 301.714 1.00 152.82 ? 78  PRO B N   1 
ATOM   6721  C  CA  . PRO B 1 78  ? 246.157 230.729 303.015 1.00 152.82 ? 78  PRO B CA  1 
ATOM   6722  C  C   . PRO B 1 78  ? 245.761 232.184 303.170 1.00 152.82 ? 78  PRO B C   1 
ATOM   6723  O  O   . PRO B 1 78  ? 245.500 232.632 304.296 1.00 152.82 ? 78  PRO B O   1 
ATOM   6724  C  CB  . PRO B 1 78  ? 247.680 230.552 303.044 1.00 152.82 ? 78  PRO B CB  1 
ATOM   6725  C  CG  . PRO B 1 78  ? 247.926 229.379 302.186 1.00 152.82 ? 78  PRO B CG  1 
ATOM   6726  C  CD  . PRO B 1 78  ? 246.923 229.480 301.076 1.00 152.82 ? 78  PRO B CD  1 
ATOM   6727  N  N   . GLU B 1 79  ? 245.711 232.941 302.073 1.00 155.20 ? 79  GLU B N   1 
ATOM   6728  C  CA  . GLU B 1 79  ? 245.159 234.288 302.141 1.00 155.20 ? 79  GLU B CA  1 
ATOM   6729  C  C   . GLU B 1 79  ? 243.705 234.244 302.585 1.00 155.20 ? 79  GLU B C   1 
ATOM   6730  O  O   . GLU B 1 79  ? 243.272 235.042 303.424 1.00 155.20 ? 79  GLU B O   1 
ATOM   6731  C  CB  . GLU B 1 79  ? 245.294 234.982 300.784 1.00 155.20 ? 79  GLU B CB  1 
ATOM   6732  C  CG  . GLU B 1 79  ? 244.700 236.383 300.733 1.00 155.20 ? 79  GLU B CG  1 
ATOM   6733  C  CD  . GLU B 1 79  ? 245.648 237.449 301.252 1.00 155.20 ? 79  GLU B CD  1 
ATOM   6734  O  OE1 . GLU B 1 79  ? 246.668 237.093 301.880 1.00 155.20 ? 79  GLU B OE1 1 
ATOM   6735  O  OE2 . GLU B 1 79  ? 245.372 238.647 301.032 1.00 155.20 ? 79  GLU B OE2 1 
ATOM   6736  N  N   . TYR B 1 80  ? 242.937 233.298 302.044 1.00 153.52 ? 80  TYR B N   1 
ATOM   6737  C  CA  . TYR B 1 80  ? 241.559 233.124 302.486 1.00 153.52 ? 80  TYR B CA  1 
ATOM   6738  C  C   . TYR B 1 80  ? 241.506 232.714 303.951 1.00 153.52 ? 80  TYR B C   1 
ATOM   6739  O  O   . TYR B 1 80  ? 240.613 233.137 304.693 1.00 153.52 ? 80  TYR B O   1 
ATOM   6740  C  CB  . TYR B 1 80  ? 240.861 232.085 301.610 1.00 153.52 ? 80  TYR B CB  1 
ATOM   6741  C  CG  . TYR B 1 80  ? 240.757 232.484 300.156 1.00 153.52 ? 80  TYR B CG  1 
ATOM   6742  C  CD1 . TYR B 1 80  ? 240.853 233.814 299.772 1.00 153.52 ? 80  TYR B CD1 1 
ATOM   6743  C  CD2 . TYR B 1 80  ? 240.574 231.529 299.166 1.00 153.52 ? 80  TYR B CD2 1 
ATOM   6744  C  CE1 . TYR B 1 80  ? 240.761 234.184 298.444 1.00 153.52 ? 80  TYR B CE1 1 
ATOM   6745  C  CE2 . TYR B 1 80  ? 240.480 231.888 297.835 1.00 153.52 ? 80  TYR B CE2 1 
ATOM   6746  C  CZ  . TYR B 1 80  ? 240.575 233.217 297.480 1.00 153.52 ? 80  TYR B CZ  1 
ATOM   6747  O  OH  . TYR B 1 80  ? 240.483 233.581 296.156 1.00 153.52 ? 80  TYR B OH  1 
ATOM   6748  N  N   . ILE B 1 81  ? 242.461 231.888 304.381 1.00 153.89 ? 81  ILE B N   1 
ATOM   6749  C  CA  . ILE B 1 81  ? 242.492 231.421 305.763 1.00 153.89 ? 81  ILE B CA  1 
ATOM   6750  C  C   . ILE B 1 81  ? 242.699 232.588 306.714 1.00 153.89 ? 81  ILE B C   1 
ATOM   6751  O  O   . ILE B 1 81  ? 241.991 232.726 307.718 1.00 153.89 ? 81  ILE B O   1 
ATOM   6752  C  CB  . ILE B 1 81  ? 243.583 230.348 305.934 1.00 153.89 ? 81  ILE B CB  1 
ATOM   6753  C  CG1 . ILE B 1 81  ? 243.061 228.983 305.480 1.00 153.89 ? 81  ILE B CG1 1 
ATOM   6754  C  CG2 . ILE B 1 81  ? 244.062 230.292 307.375 1.00 153.89 ? 81  ILE B CG2 1 
ATOM   6755  C  CD1 . ILE B 1 81  ? 244.103 227.887 305.511 1.00 153.89 ? 81  ILE B CD1 1 
ATOM   6756  N  N   . ARG B 1 82  ? 243.664 233.456 306.409 1.00 156.26 ? 82  ARG B N   1 
ATOM   6757  C  CA  . ARG B 1 82  ? 243.894 234.610 307.270 1.00 156.26 ? 82  ARG B CA  1 
ATOM   6758  C  C   . ARG B 1 82  ? 242.756 235.620 307.166 1.00 156.26 ? 82  ARG B C   1 
ATOM   6759  O  O   . ARG B 1 82  ? 242.419 236.275 308.160 1.00 156.26 ? 82  ARG B O   1 
ATOM   6760  C  CB  . ARG B 1 82  ? 245.239 235.264 306.943 1.00 156.26 ? 82  ARG B CB  1 
ATOM   6761  C  CG  . ARG B 1 82  ? 245.331 235.902 305.570 1.00 156.26 ? 82  ARG B CG  1 
ATOM   6762  C  CD  . ARG B 1 82  ? 246.490 236.883 305.495 1.00 156.26 ? 82  ARG B CD  1 
ATOM   6763  N  NE  . ARG B 1 82  ? 246.162 238.163 306.111 1.00 156.26 ? 82  ARG B NE  1 
ATOM   6764  C  CZ  . ARG B 1 82  ? 245.915 239.277 305.435 1.00 156.26 ? 82  ARG B CZ  1 
ATOM   6765  N  NH1 . ARG B 1 82  ? 245.951 239.306 304.113 1.00 156.26 ? 82  ARG B NH1 1 
ATOM   6766  N  NH2 . ARG B 1 82  ? 245.626 240.390 306.104 1.00 156.26 ? 82  ARG B NH2 1 
ATOM   6767  N  N   . HIS B 1 83  ? 242.143 235.751 305.985 1.00 157.16 ? 83  HIS B N   1 
ATOM   6768  C  CA  . HIS B 1 83  ? 241.018 236.666 305.833 1.00 157.16 ? 83  HIS B CA  1 
ATOM   6769  C  C   . HIS B 1 83  ? 239.824 236.214 306.660 1.00 157.16 ? 83  HIS B C   1 
ATOM   6770  O  O   . HIS B 1 83  ? 239.114 237.044 307.238 1.00 157.16 ? 83  HIS B O   1 
ATOM   6771  C  CB  . HIS B 1 83  ? 240.637 236.787 304.357 1.00 157.16 ? 83  HIS B CB  1 
ATOM   6772  C  CG  . HIS B 1 83  ? 239.462 237.681 304.108 1.00 157.16 ? 83  HIS B CG  1 
ATOM   6773  N  ND1 . HIS B 1 83  ? 238.161 237.227 304.138 1.00 157.16 ? 83  HIS B ND1 1 
ATOM   6774  C  CD2 . HIS B 1 83  ? 239.392 239.003 303.825 1.00 157.16 ? 83  HIS B CD2 1 
ATOM   6775  C  CE1 . HIS B 1 83  ? 237.340 238.231 303.883 1.00 157.16 ? 83  HIS B CE1 1 
ATOM   6776  N  NE2 . HIS B 1 83  ? 238.062 239.320 303.690 1.00 157.16 ? 83  HIS B NE2 1 
ATOM   6777  N  N   . ASN B 1 84  ? 239.576 234.904 306.715 1.00 155.26 ? 84  ASN B N   1 
ATOM   6778  C  CA  . ASN B 1 84  ? 238.490 234.394 307.544 1.00 155.26 ? 84  ASN B CA  1 
ATOM   6779  C  C   . ASN B 1 84  ? 238.735 234.683 309.017 1.00 155.26 ? 84  ASN B C   1 
ATOM   6780  O  O   . ASN B 1 84  ? 237.802 235.043 309.743 1.00 155.26 ? 84  ASN B O   1 
ATOM   6781  C  CB  . ASN B 1 84  ? 238.315 232.892 307.315 1.00 155.26 ? 84  ASN B CB  1 
ATOM   6782  C  CG  . ASN B 1 84  ? 237.102 232.330 308.032 1.00 155.26 ? 84  ASN B CG  1 
ATOM   6783  O  OD1 . ASN B 1 84  ? 237.139 232.078 309.236 1.00 155.26 ? 84  ASN B OD1 1 
ATOM   6784  N  ND2 . ASN B 1 84  ? 236.018 232.131 307.293 1.00 155.26 ? 84  ASN B ND2 1 
ATOM   6785  N  N   . ARG B 1 85  ? 239.978 234.526 309.476 1.00 154.19 ? 85  ARG B N   1 
ATOM   6786  C  CA  . ARG B 1 85  ? 240.300 234.844 310.862 1.00 154.19 ? 85  ARG B CA  1 
ATOM   6787  C  C   . ARG B 1 85  ? 240.115 236.330 311.143 1.00 154.19 ? 85  ARG B C   1 
ATOM   6788  O  O   . ARG B 1 85  ? 239.569 236.712 312.185 1.00 154.19 ? 85  ARG B O   1 
ATOM   6789  C  CB  . ARG B 1 85  ? 241.730 234.412 311.181 1.00 154.19 ? 85  ARG B CB  1 
ATOM   6790  C  CG  . ARG B 1 85  ? 242.050 232.985 310.790 1.00 154.19 ? 85  ARG B CG  1 
ATOM   6791  C  CD  . ARG B 1 85  ? 241.640 232.014 311.879 1.00 154.19 ? 85  ARG B CD  1 
ATOM   6792  N  NE  . ARG B 1 85  ? 242.196 230.686 311.657 1.00 154.19 ? 85  ARG B NE  1 
ATOM   6793  C  CZ  . ARG B 1 85  ? 242.400 229.794 312.615 1.00 154.19 ? 85  ARG B CZ  1 
ATOM   6794  N  NH1 . ARG B 1 85  ? 242.100 230.054 313.875 1.00 154.19 ? 85  ARG B NH1 1 
ATOM   6795  N  NH2 . ARG B 1 85  ? 242.915 228.610 312.299 1.00 154.19 ? 85  ARG B NH2 1 
ATOM   6796  N  N   . GLU B 1 86  ? 240.560 237.185 310.222 1.00 159.11 ? 86  GLU B N   1 
ATOM   6797  C  CA  . GLU B 1 86  ? 240.515 238.625 310.445 1.00 159.11 ? 86  GLU B CA  1 
ATOM   6798  C  C   . GLU B 1 86  ? 239.143 239.235 310.187 1.00 159.11 ? 86  GLU B C   1 
ATOM   6799  O  O   . GLU B 1 86  ? 238.917 240.388 310.572 1.00 159.11 ? 86  GLU B O   1 
ATOM   6800  C  CB  . GLU B 1 86  ? 241.557 239.324 309.566 1.00 159.11 ? 86  GLU B CB  1 
ATOM   6801  C  CG  . GLU B 1 86  ? 242.996 239.024 309.953 1.00 159.11 ? 86  GLU B CG  1 
ATOM   6802  C  CD  . GLU B 1 86  ? 243.999 239.730 309.062 1.00 159.11 ? 86  GLU B CD  1 
ATOM   6803  O  OE1 . GLU B 1 86  ? 243.727 240.879 308.653 1.00 159.11 ? 86  GLU B OE1 1 
ATOM   6804  O  OE2 . GLU B 1 86  ? 245.059 239.137 308.771 1.00 159.11 ? 86  GLU B OE2 1 
ATOM   6805  N  N   . GLY B 1 87  ? 238.230 238.502 309.547 1.00 160.27 ? 87  GLY B N   1 
ATOM   6806  C  CA  . GLY B 1 87  ? 236.920 239.055 309.252 1.00 160.27 ? 87  GLY B CA  1 
ATOM   6807  C  C   . GLY B 1 87  ? 236.077 239.309 310.484 1.00 160.27 ? 87  GLY B C   1 
ATOM   6808  O  O   . GLY B 1 87  ? 235.367 240.317 310.556 1.00 160.27 ? 87  GLY B O   1 
ATOM   6809  N  N   . GLY B 1 88  ? 236.139 238.411 311.464 1.00 157.08 ? 88  GLY B N   1 
ATOM   6810  C  CA  . GLY B 1 88  ? 235.342 238.536 312.663 1.00 157.08 ? 88  GLY B CA  1 
ATOM   6811  C  C   . GLY B 1 88  ? 233.941 237.975 312.568 1.00 157.08 ? 88  GLY B C   1 
ATOM   6812  O  O   . GLY B 1 88  ? 233.199 238.039 313.556 1.00 157.08 ? 88  GLY B O   1 
ATOM   6813  N  N   . LYS B 1 89  ? 233.551 237.432 311.417 1.00 153.35 ? 89  LYS B N   1 
ATOM   6814  C  CA  . LYS B 1 89  ? 232.228 236.842 311.279 1.00 153.35 ? 89  LYS B CA  1 
ATOM   6815  C  C   . LYS B 1 89  ? 232.121 235.573 312.117 1.00 153.35 ? 89  LYS B C   1 
ATOM   6816  O  O   . LYS B 1 89  ? 233.089 234.823 312.267 1.00 153.35 ? 89  LYS B O   1 
ATOM   6817  C  CB  . LYS B 1 89  ? 231.928 236.540 309.810 1.00 153.35 ? 89  LYS B CB  1 
ATOM   6818  C  CG  . LYS B 1 89  ? 232.857 235.519 309.172 1.00 153.35 ? 89  LYS B CG  1 
ATOM   6819  C  CD  . LYS B 1 89  ? 232.587 235.386 307.682 1.00 153.35 ? 89  LYS B CD  1 
ATOM   6820  C  CE  . LYS B 1 89  ? 233.327 234.199 307.089 1.00 153.35 ? 89  LYS B CE  1 
ATOM   6821  N  NZ  . LYS B 1 89  ? 233.102 234.082 305.621 1.00 153.35 ? 89  LYS B NZ  1 
ATOM   6822  N  N   . ALA B 1 90  ? 230.934 235.342 312.673 1.00 152.85 ? 90  ALA B N   1 
ATOM   6823  C  CA  . ALA B 1 90  ? 230.696 234.211 313.558 1.00 152.85 ? 90  ALA B CA  1 
ATOM   6824  C  C   . ALA B 1 90  ? 230.168 232.981 312.832 1.00 152.85 ? 90  ALA B C   1 
ATOM   6825  O  O   . ALA B 1 90  ? 229.905 231.964 313.482 1.00 152.85 ? 90  ALA B O   1 
ATOM   6826  C  CB  . ALA B 1 90  ? 229.719 234.609 314.669 1.00 152.85 ? 90  ALA B CB  1 
ATOM   6827  N  N   . ARG B 1 91  ? 230.007 233.042 311.513 1.00 152.18 ? 91  ARG B N   1 
ATOM   6828  C  CA  . ARG B 1 91  ? 229.487 231.923 310.743 1.00 152.18 ? 91  ARG B CA  1 
ATOM   6829  C  C   . ARG B 1 91  ? 230.348 231.697 309.508 1.00 152.18 ? 91  ARG B C   1 
ATOM   6830  O  O   . ARG B 1 91  ? 231.007 232.610 309.005 1.00 152.18 ? 91  ARG B O   1 
ATOM   6831  C  CB  . ARG B 1 91  ? 228.024 232.149 310.332 1.00 152.18 ? 91  ARG B CB  1 
ATOM   6832  C  CG  . ARG B 1 91  ? 227.020 231.893 311.447 1.00 152.18 ? 91  ARG B CG  1 
ATOM   6833  C  CD  . ARG B 1 91  ? 226.482 230.466 311.414 1.00 152.18 ? 91  ARG B CD  1 
ATOM   6834  N  NE  . ARG B 1 91  ? 227.541 229.465 311.480 1.00 152.18 ? 91  ARG B NE  1 
ATOM   6835  C  CZ  . ARG B 1 91  ? 228.230 229.170 312.575 1.00 152.18 ? 91  ARG B CZ  1 
ATOM   6836  N  NH1 . ARG B 1 91  ? 227.995 229.779 313.726 1.00 152.18 ? 91  ARG B NH1 1 
ATOM   6837  N  NH2 . ARG B 1 91  ? 229.182 228.243 312.512 1.00 152.18 ? 91  ARG B NH2 1 
ATOM   6838  N  N   . VAL B 1 92  ? 230.330 230.458 309.026 1.00 145.19 ? 92  VAL B N   1 
ATOM   6839  C  CA  . VAL B 1 92  ? 231.099 230.047 307.858 1.00 145.19 ? 92  VAL B CA  1 
ATOM   6840  C  C   . VAL B 1 92  ? 230.175 230.030 306.650 1.00 145.19 ? 92  VAL B C   1 
ATOM   6841  O  O   . VAL B 1 92  ? 229.151 229.335 306.650 1.00 145.19 ? 92  VAL B O   1 
ATOM   6842  C  CB  . VAL B 1 92  ? 231.747 228.669 308.076 1.00 145.19 ? 92  VAL B CB  1 
ATOM   6843  C  CG1 . VAL B 1 92  ? 232.316 228.135 306.771 1.00 145.19 ? 92  VAL B CG1 1 
ATOM   6844  C  CG2 . VAL B 1 92  ? 232.829 228.755 309.142 1.00 145.19 ? 92  VAL B CG2 1 
ATOM   6845  N  N   . GLU B 1 93  ? 230.534 230.793 305.620 1.00 142.41 ? 93  GLU B N   1 
ATOM   6846  C  CA  . GLU B 1 93  ? 229.764 230.852 304.386 1.00 142.41 ? 93  GLU B CA  1 
ATOM   6847  C  C   . GLU B 1 93  ? 230.425 230.137 303.219 1.00 142.41 ? 93  GLU B C   1 
ATOM   6848  O  O   . GLU B 1 93  ? 229.732 229.781 302.263 1.00 142.41 ? 93  GLU B O   1 
ATOM   6849  C  CB  . GLU B 1 93  ? 229.501 232.313 303.986 1.00 142.41 ? 93  GLU B CB  1 
ATOM   6850  C  CG  . GLU B 1 93  ? 228.634 233.079 304.970 1.00 142.41 ? 93  GLU B CG  1 
ATOM   6851  C  CD  . GLU B 1 93  ? 228.785 234.581 304.831 1.00 142.41 ? 93  GLU B CD  1 
ATOM   6852  O  OE1 . GLU B 1 93  ? 229.936 235.062 304.778 1.00 142.41 ? 93  GLU B OE1 1 
ATOM   6853  O  OE2 . GLU B 1 93  ? 227.752 235.281 304.775 1.00 142.41 ? 93  GLU B OE2 1 
ATOM   6854  N  N   . GLY B 1 94  ? 231.734 229.917 303.269 1.00 140.13 ? 94  GLY B N   1 
ATOM   6855  C  CA  . GLY B 1 94  ? 232.413 229.215 302.202 1.00 140.13 ? 94  GLY B CA  1 
ATOM   6856  C  C   . GLY B 1 94  ? 232.161 227.722 302.247 1.00 140.13 ? 94  GLY B C   1 
ATOM   6857  O  O   . GLY B 1 94  ? 231.505 227.191 303.145 1.00 140.13 ? 94  GLY B O   1 
ATOM   6858  N  N   . MET B 1 95  ? 232.685 227.037 301.229 1.00 139.40 ? 95  MET B N   1 
ATOM   6859  C  CA  . MET B 1 95  ? 232.550 225.591 301.088 1.00 139.40 ? 95  MET B CA  1 
ATOM   6860  C  C   . MET B 1 95  ? 231.089 225.169 300.983 1.00 139.40 ? 95  MET B C   1 
ATOM   6861  O  O   . MET B 1 95  ? 230.769 223.986 301.136 1.00 139.40 ? 95  MET B O   1 
ATOM   6862  C  CB  . MET B 1 95  ? 233.219 224.863 302.258 1.00 139.40 ? 95  MET B CB  1 
ATOM   6863  C  CG  . MET B 1 95  ? 234.682 224.527 302.040 1.00 139.40 ? 95  MET B CG  1 
ATOM   6864  S  SD  . MET B 1 95  ? 235.557 224.201 303.582 1.00 139.40 ? 95  MET B SD  1 
ATOM   6865  C  CE  . MET B 1 95  ? 237.053 223.434 302.964 1.00 139.40 ? 95  MET B CE  1 
ATOM   6866  N  N   . SER B 1 96  ? 230.194 226.126 300.726 1.00 137.10 ? 96  SER B N   1 
ATOM   6867  C  CA  . SER B 1 96  ? 228.779 225.794 300.599 1.00 137.10 ? 96  SER B CA  1 
ATOM   6868  C  C   . SER B 1 96  ? 228.507 224.985 299.339 1.00 137.10 ? 96  SER B C   1 
ATOM   6869  O  O   . SER B 1 96  ? 227.648 224.096 299.345 1.00 137.10 ? 96  SER B O   1 
ATOM   6870  C  CB  . SER B 1 96  ? 227.937 227.069 300.606 1.00 137.10 ? 96  SER B CB  1 
ATOM   6871  O  OG  . SER B 1 96  ? 228.350 227.958 299.584 1.00 137.10 ? 96  SER B OG  1 
ATOM   6872  N  N   . ALA B 1 97  ? 229.219 225.276 298.257 1.00 131.72 ? 97  ALA B N   1 
ATOM   6873  C  CA  . ALA B 1 97  ? 229.066 224.563 297.000 1.00 131.72 ? 97  ALA B CA  1 
ATOM   6874  C  C   . ALA B 1 97  ? 230.126 223.475 296.871 1.00 131.72 ? 97  ALA B C   1 
ATOM   6875  O  O   . ALA B 1 97  ? 230.974 223.282 297.745 1.00 131.72 ? 97  ALA B O   1 
ATOM   6876  C  CB  . ALA B 1 97  ? 229.144 225.533 295.818 1.00 131.72 ? 97  ALA B CB  1 
ATOM   6877  N  N   . GLU B 1 98  ? 230.064 222.756 295.754 1.00 124.88 ? 98  GLU B N   1 
ATOM   6878  C  CA  . GLU B 1 98  ? 231.014 221.685 295.500 1.00 124.88 ? 98  GLU B CA  1 
ATOM   6879  C  C   . GLU B 1 98  ? 232.416 222.244 295.294 1.00 124.88 ? 98  GLU B C   1 
ATOM   6880  O  O   . GLU B 1 98  ? 232.601 223.365 294.813 1.00 124.88 ? 98  GLU B O   1 
ATOM   6881  C  CB  . GLU B 1 98  ? 230.584 220.881 294.274 1.00 124.88 ? 98  GLU B CB  1 
ATOM   6882  C  CG  . GLU B 1 98  ? 230.579 221.681 292.982 1.00 124.88 ? 98  GLU B CG  1 
ATOM   6883  C  CD  . GLU B 1 98  ? 229.263 222.392 292.740 1.00 124.88 ? 98  GLU B CD  1 
ATOM   6884  O  OE1 . GLU B 1 98  ? 228.458 222.497 293.690 1.00 124.88 ? 98  GLU B OE1 1 
ATOM   6885  O  OE2 . GLU B 1 98  ? 229.032 222.846 291.600 1.00 124.88 ? 98  GLU B OE2 1 
ATOM   6886  N  N   . LEU B 1 99  ? 233.413 221.449 295.672 1.00 124.92 ? 99  LEU B N   1 
ATOM   6887  C  CA  . LEU B 1 99  ? 234.809 221.809 295.490 1.00 124.92 ? 99  LEU B CA  1 
ATOM   6888  C  C   . LEU B 1 99  ? 235.562 220.633 294.891 1.00 124.92 ? 99  LEU B C   1 
ATOM   6889  O  O   . LEU B 1 99  ? 235.267 219.472 295.182 1.00 124.92 ? 99  LEU B O   1 
ATOM   6890  C  CB  . LEU B 1 99  ? 235.459 222.224 296.810 1.00 124.92 ? 99  LEU B CB  1 
ATOM   6891  C  CG  . LEU B 1 99  ? 235.056 223.595 297.350 1.00 124.92 ? 99  LEU B CG  1 
ATOM   6892  C  CD1 . LEU B 1 99  ? 235.725 223.850 298.687 1.00 124.92 ? 99  LEU B CD1 1 
ATOM   6893  C  CD2 . LEU B 1 99  ? 235.405 224.690 296.355 1.00 124.92 ? 99  LEU B CD2 1 
ATOM   6894  N  N   . GLN B 1 100 ? 236.547 220.944 294.055 1.00 124.40 ? 100 GLN B N   1 
ATOM   6895  C  CA  . GLN B 1 100 ? 237.349 219.924 293.391 1.00 124.40 ? 100 GLN B CA  1 
ATOM   6896  C  C   . GLN B 1 100 ? 238.500 219.531 294.308 1.00 124.40 ? 100 GLN B C   1 
ATOM   6897  O  O   . GLN B 1 100 ? 239.376 220.350 294.604 1.00 124.40 ? 100 GLN B O   1 
ATOM   6898  C  CB  . GLN B 1 100 ? 237.864 220.431 292.047 1.00 124.40 ? 100 GLN B CB  1 
ATOM   6899  C  CG  . GLN B 1 100 ? 236.972 220.070 290.880 1.00 124.40 ? 100 GLN B CG  1 
ATOM   6900  C  CD  . GLN B 1 100 ? 237.070 218.605 290.510 1.00 124.40 ? 100 GLN B CD  1 
ATOM   6901  O  OE1 . GLN B 1 100 ? 236.342 217.768 291.043 1.00 124.40 ? 100 GLN B OE1 1 
ATOM   6902  N  NE2 . GLN B 1 100 ? 237.973 218.287 289.590 1.00 124.40 ? 100 GLN B NE2 1 
ATOM   6903  N  N   . LEU B 1 101 ? 238.502 218.278 294.752 1.00 128.67 ? 101 LEU B N   1 
ATOM   6904  C  CA  . LEU B 1 101 ? 239.531 217.778 295.652 1.00 128.67 ? 101 LEU B CA  1 
ATOM   6905  C  C   . LEU B 1 101 ? 240.529 216.938 294.865 1.00 128.67 ? 101 LEU B C   1 
ATOM   6906  O  O   . LEU B 1 101 ? 240.172 215.889 294.320 1.00 128.67 ? 101 LEU B O   1 
ATOM   6907  C  CB  . LEU B 1 101 ? 238.907 216.959 296.781 1.00 128.67 ? 101 LEU B CB  1 
ATOM   6908  C  CG  . LEU B 1 101 ? 239.845 216.452 297.880 1.00 128.67 ? 101 LEU B CG  1 
ATOM   6909  C  CD1 . LEU B 1 101 ? 239.198 216.627 299.244 1.00 128.67 ? 101 LEU B CD1 1 
ATOM   6910  C  CD2 . LEU B 1 101 ? 240.224 214.996 297.653 1.00 128.67 ? 101 LEU B CD2 1 
ATOM   6911  N  N   . GLU B 1 102 ? 241.778 217.397 294.819 1.00 134.16 ? 102 GLU B N   1 
ATOM   6912  C  CA  . GLU B 1 102 ? 242.861 216.673 294.162 1.00 134.16 ? 102 GLU B CA  1 
ATOM   6913  C  C   . GLU B 1 102 ? 243.575 215.822 295.205 1.00 134.16 ? 102 GLU B C   1 
ATOM   6914  O  O   . GLU B 1 102 ? 244.096 216.348 296.194 1.00 134.16 ? 102 GLU B O   1 
ATOM   6915  C  CB  . GLU B 1 102 ? 243.830 217.642 293.492 1.00 134.16 ? 102 GLU B CB  1 
ATOM   6916  C  CG  . GLU B 1 102 ? 244.997 216.966 292.793 1.00 134.16 ? 102 GLU B CG  1 
ATOM   6917  C  CD  . GLU B 1 102 ? 245.937 217.959 292.138 1.00 134.16 ? 102 GLU B CD  1 
ATOM   6918  O  OE1 . GLU B 1 102 ? 246.415 218.877 292.838 1.00 134.16 ? 102 GLU B OE1 1 
ATOM   6919  O  OE2 . GLU B 1 102 ? 246.198 217.823 290.924 1.00 134.16 ? 102 GLU B OE2 1 
ATOM   6920  N  N   . LYS B 1 103 ? 243.603 214.511 294.988 1.00 131.45 ? 103 LYS B N   1 
ATOM   6921  C  CA  . LYS B 1 103 ? 244.254 213.627 295.939 1.00 131.45 ? 103 LYS B CA  1 
ATOM   6922  C  C   . LYS B 1 103 ? 245.748 213.523 295.639 1.00 131.45 ? 103 LYS B C   1 
ATOM   6923  O  O   . LYS B 1 103 ? 246.292 214.231 294.787 1.00 131.45 ? 103 LYS B O   1 
ATOM   6924  C  CB  . LYS B 1 103 ? 243.595 212.249 295.930 1.00 131.45 ? 103 LYS B CB  1 
ATOM   6925  C  CG  . LYS B 1 103 ? 243.571 211.580 294.577 1.00 131.45 ? 103 LYS B CG  1 
ATOM   6926  C  CD  . LYS B 1 103 ? 243.138 210.128 294.685 1.00 131.45 ? 103 LYS B CD  1 
ATOM   6927  C  CE  . LYS B 1 103 ? 241.642 210.016 294.930 1.00 131.45 ? 103 LYS B CE  1 
ATOM   6928  N  NZ  . LYS B 1 103 ? 240.854 210.488 293.758 1.00 131.45 ? 103 LYS B NZ  1 
ATOM   6929  N  N   . LYS B 1 104 ? 246.411 212.615 296.360 1.00 133.03 ? 104 LYS B N   1 
ATOM   6930  C  CA  . LYS B 1 104 ? 247.870 212.560 296.345 1.00 133.03 ? 104 LYS B CA  1 
ATOM   6931  C  C   . LYS B 1 104 ? 248.415 212.247 294.959 1.00 133.03 ? 104 LYS B C   1 
ATOM   6932  O  O   . LYS B 1 104 ? 249.408 212.842 294.526 1.00 133.03 ? 104 LYS B O   1 
ATOM   6933  C  CB  . LYS B 1 104 ? 248.365 211.525 297.355 1.00 133.03 ? 104 LYS B CB  1 
ATOM   6934  C  CG  . LYS B 1 104 ? 249.869 211.546 297.573 1.00 133.03 ? 104 LYS B CG  1 
ATOM   6935  C  CD  . LYS B 1 104 ? 250.276 210.629 298.714 1.00 133.03 ? 104 LYS B CD  1 
ATOM   6936  C  CE  . LYS B 1 104 ? 251.775 210.681 298.958 1.00 133.03 ? 104 LYS B CE  1 
ATOM   6937  N  NZ  . LYS B 1 104 ? 252.170 209.885 300.152 1.00 133.03 ? 104 LYS B NZ  1 
ATOM   6938  N  N   . ASP B 1 105 ? 247.782 211.317 294.245 1.00 131.28 ? 105 ASP B N   1 
ATOM   6939  C  CA  . ASP B 1 105 ? 248.287 210.936 292.932 1.00 131.28 ? 105 ASP B CA  1 
ATOM   6940  C  C   . ASP B 1 105 ? 248.144 212.048 291.902 1.00 131.28 ? 105 ASP B C   1 
ATOM   6941  O  O   . ASP B 1 105 ? 248.716 211.938 290.813 1.00 131.28 ? 105 ASP B O   1 
ATOM   6942  C  CB  . ASP B 1 105 ? 247.579 209.670 292.439 1.00 131.28 ? 105 ASP B CB  1 
ATOM   6943  C  CG  . ASP B 1 105 ? 246.097 209.883 292.166 1.00 131.28 ? 105 ASP B CG  1 
ATOM   6944  O  OD1 . ASP B 1 105 ? 245.594 211.011 292.347 1.00 131.28 ? 105 ASP B OD1 1 
ATOM   6945  O  OD2 . ASP B 1 105 ? 245.428 208.908 291.765 1.00 131.28 ? 105 ASP B OD2 1 
ATOM   6946  N  N   . GLY B 1 106 ? 247.400 213.104 292.219 1.00 129.43 ? 106 GLY B N   1 
ATOM   6947  C  CA  . GLY B 1 106 ? 247.129 214.175 291.291 1.00 129.43 ? 106 GLY B CA  1 
ATOM   6948  C  C   . GLY B 1 106 ? 245.740 214.150 290.696 1.00 129.43 ? 106 GLY B C   1 
ATOM   6949  O  O   . GLY B 1 106 ? 245.315 215.156 290.116 1.00 129.43 ? 106 GLY B O   1 
ATOM   6950  N  N   . SER B 1 107 ? 245.024 213.037 290.818 1.00 128.70 ? 107 SER B N   1 
ATOM   6951  C  CA  . SER B 1 107 ? 243.662 212.978 290.322 1.00 128.70 ? 107 SER B CA  1 
ATOM   6952  C  C   . SER B 1 107 ? 242.741 213.797 291.222 1.00 128.70 ? 107 SER B C   1 
ATOM   6953  O  O   . SER B 1 107 ? 242.989 213.977 292.417 1.00 128.70 ? 107 SER B O   1 
ATOM   6954  C  CB  . SER B 1 107 ? 243.185 211.531 290.231 1.00 128.70 ? 107 SER B CB  1 
ATOM   6955  O  OG  . SER B 1 107 ? 243.139 210.930 291.510 1.00 128.70 ? 107 SER B OG  1 
ATOM   6956  N  N   . LYS B 1 108 ? 241.661 214.296 290.630 1.00 127.70 ? 108 LYS B N   1 
ATOM   6957  C  CA  . LYS B 1 108 ? 240.745 215.192 291.314 1.00 127.70 ? 108 LYS B CA  1 
ATOM   6958  C  C   . LYS B 1 108 ? 239.373 214.543 291.417 1.00 127.70 ? 108 LYS B C   1 
ATOM   6959  O  O   . LYS B 1 108 ? 238.969 213.755 290.559 1.00 127.70 ? 108 LYS B O   1 
ATOM   6960  C  CB  . LYS B 1 108 ? 240.632 216.537 290.588 1.00 127.70 ? 108 LYS B CB  1 
ATOM   6961  C  CG  . LYS B 1 108 ? 241.933 217.312 290.510 1.00 127.70 ? 108 LYS B CG  1 
ATOM   6962  C  CD  . LYS B 1 108 ? 241.758 218.609 289.737 1.00 127.70 ? 108 LYS B CD  1 
ATOM   6963  C  CE  . LYS B 1 108 ? 243.036 219.433 289.745 1.00 127.70 ? 108 LYS B CE  1 
ATOM   6964  N  NZ  . LYS B 1 108 ? 242.912 220.660 288.911 1.00 127.70 ? 108 LYS B NZ  1 
ATOM   6965  N  N   . ILE B 1 109 ? 238.656 214.887 292.487 1.00 122.78 ? 109 ILE B N   1 
ATOM   6966  C  CA  . ILE B 1 109 ? 237.296 214.414 292.723 1.00 122.78 ? 109 ILE B CA  1 
ATOM   6967  C  C   . ILE B 1 109 ? 236.465 215.577 293.249 1.00 122.78 ? 109 ILE B C   1 
ATOM   6968  O  O   . ILE B 1 109 ? 236.984 216.653 293.552 1.00 122.78 ? 109 ILE B O   1 
ATOM   6969  C  CB  . ILE B 1 109 ? 237.249 213.232 293.716 1.00 122.78 ? 109 ILE B CB  1 
ATOM   6970  C  CG1 . ILE B 1 109 ? 238.054 213.560 294.974 1.00 122.78 ? 109 ILE B CG1 1 
ATOM   6971  C  CG2 . ILE B 1 109 ? 237.762 211.959 293.060 1.00 122.78 ? 109 ILE B CG2 1 
ATOM   6972  C  CD1 . ILE B 1 109 ? 237.872 212.557 296.092 1.00 122.78 ? 109 ILE B CD1 1 
ATOM   6973  N  N   . TRP B 1 110 ? 235.160 215.357 293.358 1.00 112.61 ? 110 TRP B N   1 
ATOM   6974  C  CA  . TRP B 1 110 ? 234.242 216.345 293.906 1.00 112.61 ? 110 TRP B CA  1 
ATOM   6975  C  C   . TRP B 1 110 ? 233.904 215.980 295.346 1.00 112.61 ? 110 TRP B C   1 
ATOM   6976  O  O   . TRP B 1 110 ? 233.429 214.871 295.614 1.00 112.61 ? 110 TRP B O   1 
ATOM   6977  C  CB  . TRP B 1 110 ? 232.965 216.426 293.069 1.00 112.61 ? 110 TRP B CB  1 
ATOM   6978  C  CG  . TRP B 1 110 ? 233.192 216.926 291.681 1.00 112.61 ? 110 TRP B CG  1 
ATOM   6979  C  CD1 . TRP B 1 110 ? 233.296 216.177 290.552 1.00 112.61 ? 110 TRP B CD1 1 
ATOM   6980  C  CD2 . TRP B 1 110 ? 233.336 218.289 291.275 1.00 112.61 ? 110 TRP B CD2 1 
ATOM   6981  N  NE1 . TRP B 1 110 ? 233.502 216.986 289.466 1.00 112.61 ? 110 TRP B NE1 1 
ATOM   6982  C  CE2 . TRP B 1 110 ? 233.530 218.289 289.883 1.00 112.61 ? 110 TRP B CE2 1 
ATOM   6983  C  CE3 . TRP B 1 110 ? 233.324 219.508 291.954 1.00 112.61 ? 110 TRP B CE3 1 
ATOM   6984  C  CZ2 . TRP B 1 110 ? 233.709 219.459 289.155 1.00 112.61 ? 110 TRP B CZ2 1 
ATOM   6985  C  CZ3 . TRP B 1 110 ? 233.501 220.671 291.230 1.00 112.61 ? 110 TRP B CZ3 1 
ATOM   6986  C  CH2 . TRP B 1 110 ? 233.690 220.638 289.845 1.00 112.61 ? 110 TRP B CH2 1 
ATOM   6987  N  N   . THR B 1 111 ? 234.146 216.912 296.268 1.00 120.06 ? 111 THR B N   1 
ATOM   6988  C  CA  . THR B 1 111 ? 233.901 216.692 297.687 1.00 120.06 ? 111 THR B CA  1 
ATOM   6989  C  C   . THR B 1 111 ? 233.198 217.908 298.276 1.00 120.06 ? 111 THR B C   1 
ATOM   6990  O  O   . THR B 1 111 ? 233.263 219.015 297.736 1.00 120.06 ? 111 THR B O   1 
ATOM   6991  C  CB  . THR B 1 111 ? 235.200 216.415 298.458 1.00 120.06 ? 111 THR B CB  1 
ATOM   6992  O  OG1 . THR B 1 111 ? 236.091 217.529 298.316 1.00 120.06 ? 111 THR B OG1 1 
ATOM   6993  C  CG2 . THR B 1 111 ? 235.880 215.151 297.947 1.00 120.06 ? 111 THR B CG2 1 
ATOM   6994  N  N   . ARG B 1 112 ? 232.521 217.690 299.401 1.00 118.98 ? 112 ARG B N   1 
ATOM   6995  C  CA  . ARG B 1 112 ? 231.821 218.753 300.102 1.00 118.98 ? 112 ARG B CA  1 
ATOM   6996  C  C   . ARG B 1 112 ? 232.275 218.773 301.553 1.00 118.98 ? 112 ARG B C   1 
ATOM   6997  O  O   . ARG B 1 112 ? 232.773 217.777 302.087 1.00 118.98 ? 112 ARG B O   1 
ATOM   6998  C  CB  . ARG B 1 112 ? 230.301 218.582 300.021 1.00 118.98 ? 112 ARG B CB  1 
ATOM   6999  C  CG  . ARG B 1 112 ? 229.765 218.517 298.605 1.00 118.98 ? 112 ARG B CG  1 
ATOM   7000  C  CD  . ARG B 1 112 ? 228.299 218.128 298.590 1.00 118.98 ? 112 ARG B CD  1 
ATOM   7001  N  NE  . ARG B 1 112 ? 227.557 218.762 299.672 1.00 118.98 ? 112 ARG B NE  1 
ATOM   7002  C  CZ  . ARG B 1 112 ? 227.127 220.015 299.648 1.00 118.98 ? 112 ARG B CZ  1 
ATOM   7003  N  NH1 . ARG B 1 112 ? 227.346 220.801 298.607 1.00 118.98 ? 112 ARG B NH1 1 
ATOM   7004  N  NH2 . ARG B 1 112 ? 226.458 220.492 300.694 1.00 118.98 ? 112 ARG B NH2 1 
ATOM   7005  N  N   . PHE B 1 113 ? 232.098 219.927 302.186 1.00 131.18 ? 113 PHE B N   1 
ATOM   7006  C  CA  . PHE B 1 113 ? 232.604 220.163 303.527 1.00 131.18 ? 113 PHE B CA  1 
ATOM   7007  C  C   . PHE B 1 113 ? 231.502 220.734 304.410 1.00 131.18 ? 113 PHE B C   1 
ATOM   7008  O  O   . PHE B 1 113 ? 230.554 221.365 303.935 1.00 131.18 ? 113 PHE B O   1 
ATOM   7009  C  CB  . PHE B 1 113 ? 233.801 221.124 303.515 1.00 131.18 ? 113 PHE B CB  1 
ATOM   7010  C  CG  . PHE B 1 113 ? 234.961 220.651 302.682 1.00 131.18 ? 113 PHE B CG  1 
ATOM   7011  C  CD1 . PHE B 1 113 ? 234.932 220.753 301.299 1.00 131.18 ? 113 PHE B CD1 1 
ATOM   7012  C  CD2 . PHE B 1 113 ? 236.089 220.119 303.283 1.00 131.18 ? 113 PHE B CD2 1 
ATOM   7013  C  CE1 . PHE B 1 113 ? 235.999 220.325 300.534 1.00 131.18 ? 113 PHE B CE1 1 
ATOM   7014  C  CE2 . PHE B 1 113 ? 237.162 219.693 302.522 1.00 131.18 ? 113 PHE B CE2 1 
ATOM   7015  C  CZ  . PHE B 1 113 ? 237.116 219.794 301.146 1.00 131.18 ? 113 PHE B CZ  1 
ATOM   7016  N  N   . ALA B 1 114 ? 231.646 220.499 305.712 1.00 138.05 ? 114 ALA B N   1 
ATOM   7017  C  CA  . ALA B 1 114 ? 230.770 221.035 306.749 1.00 138.05 ? 114 ALA B CA  1 
ATOM   7018  C  C   . ALA B 1 114 ? 231.605 221.708 307.829 1.00 138.05 ? 114 ALA B C   1 
ATOM   7019  O  O   . ALA B 1 114 ? 231.426 221.490 309.029 1.00 138.05 ? 114 ALA B O   1 
ATOM   7020  C  CB  . ALA B 1 114 ? 229.887 219.940 307.342 1.00 138.05 ? 114 ALA B CB  1 
ATOM   7021  N  N   . LEU B 1 115 ? 232.544 222.543 307.393 1.00 144.78 ? 115 LEU B N   1 
ATOM   7022  C  CA  . LEU B 1 115 ? 233.496 223.170 308.295 1.00 144.78 ? 115 LEU B CA  1 
ATOM   7023  C  C   . LEU B 1 115 ? 232.783 224.070 309.301 1.00 144.78 ? 115 LEU B C   1 
ATOM   7024  O  O   . LEU B 1 115 ? 231.768 224.704 309.003 1.00 144.78 ? 115 LEU B O   1 
ATOM   7025  C  CB  . LEU B 1 115 ? 234.523 223.974 307.495 1.00 144.78 ? 115 LEU B CB  1 
ATOM   7026  C  CG  . LEU B 1 115 ? 235.409 224.976 308.237 1.00 144.78 ? 115 LEU B CG  1 
ATOM   7027  C  CD1 . LEU B 1 115 ? 236.377 224.256 309.159 1.00 144.78 ? 115 LEU B CD1 1 
ATOM   7028  C  CD2 . LEU B 1 115 ? 236.155 225.858 307.252 1.00 144.78 ? 115 LEU B CD2 1 
ATOM   7029  N  N   . SER B 1 116 ? 233.328 224.105 310.515 1.00 147.25 ? 116 SER B N   1 
ATOM   7030  C  CA  . SER B 1 116 ? 232.827 224.957 311.581 1.00 147.25 ? 116 SER B CA  1 
ATOM   7031  C  C   . SER B 1 116 ? 233.998 225.680 312.226 1.00 147.25 ? 116 SER B C   1 
ATOM   7032  O  O   . SER B 1 116 ? 235.124 225.172 312.226 1.00 147.25 ? 116 SER B O   1 
ATOM   7033  C  CB  . SER B 1 116 ? 232.065 224.140 312.628 1.00 147.25 ? 116 SER B CB  1 
ATOM   7034  O  OG  . SER B 1 116 ? 230.861 223.632 312.088 1.00 147.25 ? 116 SER B OG  1 
ATOM   7035  N  N   . LYS B 1 117 ? 233.728 226.867 312.763 1.00 152.78 ? 117 LYS B N   1 
ATOM   7036  C  CA  . LYS B 1 117 ? 234.740 227.630 313.477 1.00 152.78 ? 117 LYS B CA  1 
ATOM   7037  C  C   . LYS B 1 117 ? 234.598 227.410 314.977 1.00 152.78 ? 117 LYS B C   1 
ATOM   7038  O  O   . LYS B 1 117 ? 233.512 227.567 315.543 1.00 152.78 ? 117 LYS B O   1 
ATOM   7039  C  CB  . LYS B 1 117 ? 234.618 229.118 313.150 1.00 152.78 ? 117 LYS B CB  1 
ATOM   7040  C  CG  . LYS B 1 117 ? 235.629 229.998 313.867 1.00 152.78 ? 117 LYS B CG  1 
ATOM   7041  C  CD  . LYS B 1 117 ? 235.338 231.473 313.637 1.00 152.78 ? 117 LYS B CD  1 
ATOM   7042  C  CE  . LYS B 1 117 ? 235.719 231.899 312.229 1.00 152.78 ? 117 LYS B CE  1 
ATOM   7043  N  NZ  . LYS B 1 117 ? 235.561 233.367 312.031 1.00 152.78 ? 117 LYS B NZ  1 
ATOM   7044  N  N   . VAL B 1 118 ? 235.701 227.042 315.620 1.00 153.68 ? 118 VAL B N   1 
ATOM   7045  C  CA  . VAL B 1 118 ? 235.701 226.718 317.041 1.00 153.68 ? 118 VAL B CA  1 
ATOM   7046  C  C   . VAL B 1 118 ? 236.661 227.662 317.747 1.00 153.68 ? 118 VAL B C   1 
ATOM   7047  O  O   . VAL B 1 118 ? 237.798 227.846 317.303 1.00 153.68 ? 118 VAL B O   1 
ATOM   7048  C  CB  . VAL B 1 118 ? 236.101 225.252 317.294 1.00 153.68 ? 118 VAL B CB  1 
ATOM   7049  C  CG1 . VAL B 1 118 ? 235.825 224.865 318.740 1.00 153.68 ? 118 VAL B CG1 1 
ATOM   7050  C  CG2 . VAL B 1 118 ? 235.370 224.334 316.334 1.00 153.68 ? 118 VAL B CG2 1 
ATOM   7051  N  N   . SER B 1 119 ? 236.202 228.266 318.840 1.00 158.68 ? 119 SER B N   1 
ATOM   7052  C  CA  . SER B 1 119 ? 237.016 229.162 319.651 1.00 158.68 ? 119 SER B CA  1 
ATOM   7053  C  C   . SER B 1 119 ? 237.088 228.608 321.065 1.00 158.68 ? 119 SER B C   1 
ATOM   7054  O  O   . SER B 1 119 ? 236.085 228.606 321.786 1.00 158.68 ? 119 SER B O   1 
ATOM   7055  C  CB  . SER B 1 119 ? 236.440 230.580 319.654 1.00 158.68 ? 119 SER B CB  1 
ATOM   7056  O  OG  . SER B 1 119 ? 237.252 231.458 320.413 1.00 158.68 ? 119 SER B OG  1 
ATOM   7057  N  N   . ALA B 1 120 ? 238.270 228.139 321.457 1.00 162.34 ? 120 ALA B N   1 
ATOM   7058  C  CA  . ALA B 1 120 ? 238.466 227.587 322.790 1.00 162.34 ? 120 ALA B CA  1 
ATOM   7059  C  C   . ALA B 1 120 ? 239.919 227.783 323.194 1.00 162.34 ? 120 ALA B C   1 
ATOM   7060  O  O   . ALA B 1 120 ? 240.809 227.893 322.346 1.00 162.34 ? 120 ALA B O   1 
ATOM   7061  C  CB  . ALA B 1 120 ? 238.083 226.104 322.848 1.00 162.34 ? 120 ALA B CB  1 
ATOM   7062  N  N   . GLU B 1 121 ? 240.142 227.826 324.509 1.00 162.05 ? 121 GLU B N   1 
ATOM   7063  C  CA  . GLU B 1 121 ? 241.473 228.009 325.090 1.00 162.05 ? 121 GLU B CA  1 
ATOM   7064  C  C   . GLU B 1 121 ? 242.138 229.291 324.595 1.00 162.05 ? 121 GLU B C   1 
ATOM   7065  O  O   . GLU B 1 121 ? 243.364 229.361 324.474 1.00 162.05 ? 121 GLU B O   1 
ATOM   7066  C  CB  . GLU B 1 121 ? 242.372 226.800 324.815 1.00 162.05 ? 121 GLU B CB  1 
ATOM   7067  C  CG  . GLU B 1 121 ? 241.760 225.467 325.214 1.00 162.05 ? 121 GLU B CG  1 
ATOM   7068  C  CD  . GLU B 1 121 ? 242.564 224.283 324.712 1.00 162.05 ? 121 GLU B CD  1 
ATOM   7069  O  OE1 . GLU B 1 121 ? 242.918 224.268 323.515 1.00 162.05 ? 121 GLU B OE1 1 
ATOM   7070  O  OE2 . GLU B 1 121 ? 242.842 223.368 325.516 1.00 162.05 ? 121 GLU B OE2 1 
ATOM   7071  N  N   . GLY B 1 122 ? 241.337 230.313 324.304 1.00 162.20 ? 122 GLY B N   1 
ATOM   7072  C  CA  . GLY B 1 122 ? 241.878 231.569 323.826 1.00 162.20 ? 122 GLY B CA  1 
ATOM   7073  C  C   . GLY B 1 122 ? 242.366 231.549 322.397 1.00 162.20 ? 122 GLY B C   1 
ATOM   7074  O  O   . GLY B 1 122 ? 243.044 232.488 321.973 1.00 162.20 ? 122 GLY B O   1 
ATOM   7075  N  N   . LYS B 1 123 ? 242.041 230.505 321.637 1.00 159.35 ? 123 LYS B N   1 
ATOM   7076  C  CA  . LYS B 1 123 ? 242.480 230.385 320.255 1.00 159.35 ? 123 LYS B CA  1 
ATOM   7077  C  C   . LYS B 1 123 ? 241.309 229.946 319.388 1.00 159.35 ? 123 LYS B C   1 
ATOM   7078  O  O   . LYS B 1 123 ? 240.376 229.291 319.861 1.00 159.35 ? 123 LYS B O   1 
ATOM   7079  C  CB  . LYS B 1 123 ? 243.640 229.390 320.113 1.00 159.35 ? 123 LYS B CB  1 
ATOM   7080  C  CG  . LYS B 1 123 ? 244.934 229.842 320.771 1.00 159.35 ? 123 LYS B CG  1 
ATOM   7081  C  CD  . LYS B 1 123 ? 245.998 228.759 320.693 1.00 159.35 ? 123 LYS B CD  1 
ATOM   7082  C  CE  . LYS B 1 123 ? 247.247 229.156 321.463 1.00 159.35 ? 123 LYS B CE  1 
ATOM   7083  N  NZ  . LYS B 1 123 ? 248.252 228.057 321.494 1.00 159.35 ? 123 LYS B NZ  1 
ATOM   7084  N  N   . VAL B 1 124 ? 241.372 230.311 318.111 1.00 156.77 ? 124 VAL B N   1 
ATOM   7085  C  CA  . VAL B 1 124 ? 240.325 229.999 317.145 1.00 156.77 ? 124 VAL B CA  1 
ATOM   7086  C  C   . VAL B 1 124 ? 240.744 228.766 316.358 1.00 156.77 ? 124 VAL B C   1 
ATOM   7087  O  O   . VAL B 1 124 ? 241.871 228.694 315.852 1.00 156.77 ? 124 VAL B O   1 
ATOM   7088  C  CB  . VAL B 1 124 ? 240.057 231.189 316.208 1.00 156.77 ? 124 VAL B CB  1 
ATOM   7089  C  CG1 . VAL B 1 124 ? 238.997 230.828 315.178 1.00 156.77 ? 124 VAL B CG1 1 
ATOM   7090  C  CG2 . VAL B 1 124 ? 239.636 232.411 317.010 1.00 156.77 ? 124 VAL B CG2 1 
ATOM   7091  N  N   . TYR B 1 125 ? 239.839 227.796 316.258 1.00 156.25 ? 125 TYR B N   1 
ATOM   7092  C  CA  . TYR B 1 125 ? 240.105 226.536 315.584 1.00 156.25 ? 125 TYR B CA  1 
ATOM   7093  C  C   . TYR B 1 125 ? 239.073 226.315 314.488 1.00 156.25 ? 125 TYR B C   1 
ATOM   7094  O  O   . TYR B 1 125 ? 237.954 226.831 314.542 1.00 156.25 ? 125 TYR B O   1 
ATOM   7095  C  CB  . TYR B 1 125 ? 240.078 225.357 316.566 1.00 156.25 ? 125 TYR B CB  1 
ATOM   7096  C  CG  . TYR B 1 125 ? 240.967 225.537 317.774 1.00 156.25 ? 125 TYR B CG  1 
ATOM   7097  C  CD1 . TYR B 1 125 ? 242.236 226.085 317.651 1.00 156.25 ? 125 TYR B CD1 1 
ATOM   7098  C  CD2 . TYR B 1 125 ? 240.535 225.163 319.039 1.00 156.25 ? 125 TYR B CD2 1 
ATOM   7099  C  CE1 . TYR B 1 125 ? 243.052 226.251 318.752 1.00 156.25 ? 125 TYR B CE1 1 
ATOM   7100  C  CE2 . TYR B 1 125 ? 241.344 225.327 320.147 1.00 156.25 ? 125 TYR B CE2 1 
ATOM   7101  C  CZ  . TYR B 1 125 ? 242.601 225.872 319.997 1.00 156.25 ? 125 TYR B CZ  1 
ATOM   7102  O  OH  . TYR B 1 125 ? 243.410 226.037 321.097 1.00 156.25 ? 125 TYR B OH  1 
ATOM   7103  N  N   . TYR B 1 126 ? 239.470 225.537 313.486 1.00 155.34 ? 126 TYR B N   1 
ATOM   7104  C  CA  . TYR B 1 126 ? 238.592 225.137 312.394 1.00 155.34 ? 126 TYR B CA  1 
ATOM   7105  C  C   . TYR B 1 126 ? 238.454 223.620 312.409 1.00 155.34 ? 126 TYR B C   1 
ATOM   7106  O  O   . TYR B 1 126 ? 239.461 222.903 312.371 1.00 155.34 ? 126 TYR B O   1 
ATOM   7107  C  CB  . TYR B 1 126 ? 239.135 225.614 311.047 1.00 155.34 ? 126 TYR B CB  1 
ATOM   7108  C  CG  . TYR B 1 126 ? 239.084 227.111 310.846 1.00 155.34 ? 126 TYR B CG  1 
ATOM   7109  C  CD1 . TYR B 1 126 ? 238.223 227.905 311.593 1.00 155.34 ? 126 TYR B CD1 1 
ATOM   7110  C  CD2 . TYR B 1 126 ? 239.900 227.732 309.910 1.00 155.34 ? 126 TYR B CD2 1 
ATOM   7111  C  CE1 . TYR B 1 126 ? 238.176 229.274 311.411 1.00 155.34 ? 126 TYR B CE1 1 
ATOM   7112  C  CE2 . TYR B 1 126 ? 239.860 229.100 309.721 1.00 155.34 ? 126 TYR B CE2 1 
ATOM   7113  C  CZ  . TYR B 1 126 ? 238.996 229.866 310.474 1.00 155.34 ? 126 TYR B CZ  1 
ATOM   7114  O  OH  . TYR B 1 126 ? 238.953 231.228 310.289 1.00 155.34 ? 126 TYR B OH  1 
ATOM   7115  N  N   . LEU B 1 127 ? 237.214 223.138 312.461 1.00 147.75 ? 127 LEU B N   1 
ATOM   7116  C  CA  . LEU B 1 127 ? 236.909 221.708 312.481 1.00 147.75 ? 127 LEU B CA  1 
ATOM   7117  C  C   . LEU B 1 127 ? 236.061 221.401 311.249 1.00 147.75 ? 127 LEU B C   1 
ATOM   7118  O  O   . LEU B 1 127 ? 234.901 221.800 311.159 1.00 147.75 ? 127 LEU B O   1 
ATOM   7119  C  CB  . LEU B 1 127 ? 236.191 221.316 313.770 1.00 147.75 ? 127 LEU B CB  1 
ATOM   7120  C  CG  . LEU B 1 127 ? 235.744 219.858 313.879 1.00 147.75 ? 127 LEU B CG  1 
ATOM   7121  C  CD1 . LEU B 1 127 ? 236.940 218.922 313.813 1.00 147.75 ? 127 LEU B CD1 1 
ATOM   7122  C  CD2 . LEU B 1 127 ? 234.951 219.633 315.158 1.00 147.75 ? 127 LEU B CD2 1 
ATOM   7123  N  N   . ALA B 1 128 ? 236.652 220.692 310.298 1.00 139.38 ? 128 ALA B N   1 
ATOM   7124  C  CA  . ALA B 1 128 ? 236.029 220.434 309.008 1.00 139.38 ? 128 ALA B CA  1 
ATOM   7125  C  C   . ALA B 1 128 ? 235.677 218.957 308.910 1.00 139.38 ? 128 ALA B C   1 
ATOM   7126  O  O   . ALA B 1 128 ? 236.521 218.088 309.157 1.00 139.38 ? 128 ALA B O   1 
ATOM   7127  C  CB  . ALA B 1 128 ? 236.954 220.851 307.868 1.00 139.38 ? 128 ALA B CB  1 
ATOM   7128  N  N   . LEU B 1 129 ? 234.427 218.685 308.553 1.00 134.83 ? 129 LEU B N   1 
ATOM   7129  C  CA  . LEU B 1 129 ? 233.982 217.345 308.210 1.00 134.83 ? 129 LEU B CA  1 
ATOM   7130  C  C   . LEU B 1 129 ? 233.799 217.248 306.701 1.00 134.83 ? 129 LEU B C   1 
ATOM   7131  O  O   . LEU B 1 129 ? 233.054 218.024 306.100 1.00 134.83 ? 129 LEU B O   1 
ATOM   7132  C  CB  . LEU B 1 129 ? 232.675 217.007 308.928 1.00 134.83 ? 129 LEU B CB  1 
ATOM   7133  C  CG  . LEU B 1 129 ? 232.708 217.045 310.457 1.00 134.83 ? 129 LEU B CG  1 
ATOM   7134  C  CD1 . LEU B 1 129 ? 231.318 216.814 311.029 1.00 134.83 ? 129 LEU B CD1 1 
ATOM   7135  C  CD2 . LEU B 1 129 ? 233.692 216.021 310.999 1.00 134.83 ? 129 LEU B CD2 1 
ATOM   7136  N  N   . VAL B 1 130 ? 234.477 216.283 306.098 1.00 126.81 ? 130 VAL B N   1 
ATOM   7137  C  CA  . VAL B 1 130 ? 234.593 216.181 304.650 1.00 126.81 ? 130 VAL B CA  1 
ATOM   7138  C  C   . VAL B 1 130 ? 233.865 214.931 304.195 1.00 126.81 ? 130 VAL B C   1 
ATOM   7139  O  O   . VAL B 1 130 ? 234.119 213.837 304.713 1.00 126.81 ? 130 VAL B O   1 
ATOM   7140  C  CB  . VAL B 1 130 ? 236.065 216.131 304.200 1.00 126.81 ? 130 VAL B CB  1 
ATOM   7141  C  CG1 . VAL B 1 130 ? 236.171 216.373 302.702 1.00 126.81 ? 130 VAL B CG1 1 
ATOM   7142  C  CG2 . VAL B 1 130 ? 236.894 217.137 304.983 1.00 126.81 ? 130 VAL B CG2 1 
ATOM   7143  N  N   . ARG B 1 131 ? 232.966 215.090 303.225 1.00 111.78 ? 131 ARG B N   1 
ATOM   7144  C  CA  . ARG B 1 131 ? 232.254 213.970 302.639 1.00 111.78 ? 131 ARG B CA  1 
ATOM   7145  C  C   . ARG B 1 131 ? 232.457 213.988 301.134 1.00 111.78 ? 131 ARG B C   1 
ATOM   7146  O  O   . ARG B 1 131 ? 232.775 215.025 300.546 1.00 111.78 ? 131 ARG B O   1 
ATOM   7147  C  CB  . ARG B 1 131 ? 230.760 214.006 302.976 1.00 111.78 ? 131 ARG B CB  1 
ATOM   7148  C  CG  . ARG B 1 131 ? 229.954 215.026 302.193 1.00 111.78 ? 131 ARG B CG  1 
ATOM   7149  C  CD  . ARG B 1 131 ? 228.462 214.754 302.337 1.00 111.78 ? 131 ARG B CD  1 
ATOM   7150  N  NE  . ARG B 1 131 ? 227.640 215.759 301.672 1.00 111.78 ? 131 ARG B NE  1 
ATOM   7151  C  CZ  . ARG B 1 131 ? 226.402 215.548 301.246 1.00 111.78 ? 131 ARG B CZ  1 
ATOM   7152  N  NH1 . ARG B 1 131 ? 225.806 214.378 301.406 1.00 111.78 ? 131 ARG B NH1 1 
ATOM   7153  N  NH2 . ARG B 1 131 ? 225.745 216.535 300.646 1.00 111.78 ? 131 ARG B NH2 1 
ATOM   7154  N  N   . ASP B 1 132 ? 232.294 212.821 300.522 1.00 101.90 ? 132 ASP B N   1 
ATOM   7155  C  CA  . ASP B 1 132 ? 232.450 212.695 299.083 1.00 101.90 ? 132 ASP B CA  1 
ATOM   7156  C  C   . ASP B 1 132 ? 231.126 212.956 298.379 1.00 101.90 ? 132 ASP B C   1 
ATOM   7157  O  O   . ASP B 1 132 ? 230.071 212.454 298.779 1.00 101.90 ? 132 ASP B O   1 
ATOM   7158  C  CB  . ASP B 1 132 ? 232.970 211.305 298.717 1.00 101.90 ? 132 ASP B CB  1 
ATOM   7159  C  CG  . ASP B 1 132 ? 233.202 211.139 297.225 1.00 101.90 ? 132 ASP B CG  1 
ATOM   7160  O  OD1 . ASP B 1 132 ? 233.195 212.153 296.497 1.00 101.90 ? 132 ASP B OD1 1 
ATOM   7161  O  OD2 . ASP B 1 132 ? 233.392 209.988 296.780 1.00 101.90 ? 132 ASP B OD2 1 
ATOM   7162  N  N   . ALA B 1 133 ? 231.192 213.756 297.316 1.00 93.71  ? 133 ALA B N   1 
ATOM   7163  C  CA  . ALA B 1 133 ? 230.028 214.071 296.499 1.00 93.71  ? 133 ALA B CA  1 
ATOM   7164  C  C   . ALA B 1 133 ? 230.204 213.542 295.086 1.00 93.71  ? 133 ALA B C   1 
ATOM   7165  O  O   . ALA B 1 133 ? 229.639 214.090 294.135 1.00 93.71  ? 133 ALA B O   1 
ATOM   7166  C  CB  . ALA B 1 133 ? 229.763 215.575 296.477 1.00 93.71  ? 133 ALA B CB  1 
ATOM   7167  N  N   . SER B 1 134 ? 230.997 212.482 294.933 1.00 84.41  ? 134 SER B N   1 
ATOM   7168  C  CA  . SER B 1 134 ? 231.238 211.932 293.605 1.00 84.41  ? 134 SER B CA  1 
ATOM   7169  C  C   . SER B 1 134 ? 229.937 211.479 292.964 1.00 84.41  ? 134 SER B C   1 
ATOM   7170  O  O   . SER B 1 134 ? 229.640 211.831 291.818 1.00 84.41  ? 134 SER B O   1 
ATOM   7171  C  CB  . SER B 1 134 ? 232.229 210.774 293.690 1.00 84.41  ? 134 SER B CB  1 
ATOM   7172  O  OG  . SER B 1 134 ? 231.775 209.786 294.597 1.00 84.41  ? 134 SER B OG  1 
ATOM   7173  N  N   . VAL B 1 135 ? 229.138 210.705 293.697 1.00 76.32  ? 135 VAL B N   1 
ATOM   7174  C  CA  . VAL B 1 135 ? 227.886 210.211 293.139 1.00 76.32  ? 135 VAL B CA  1 
ATOM   7175  C  C   . VAL B 1 135 ? 226.915 211.359 292.909 1.00 76.32  ? 135 VAL B C   1 
ATOM   7176  O  O   . VAL B 1 135 ? 226.146 211.350 291.943 1.00 76.32  ? 135 VAL B O   1 
ATOM   7177  C  CB  . VAL B 1 135 ? 227.286 209.120 294.043 1.00 76.32  ? 135 VAL B CB  1 
ATOM   7178  C  CG1 . VAL B 1 135 ? 226.999 209.662 295.434 1.00 76.32  ? 135 VAL B CG1 1 
ATOM   7179  C  CG2 . VAL B 1 135 ? 226.027 208.544 293.415 1.00 76.32  ? 135 VAL B CG2 1 
ATOM   7180  N  N   . GLU B 1 136 ? 226.933 212.365 293.782 1.00 76.82  ? 136 GLU B N   1 
ATOM   7181  C  CA  . GLU B 1 136 ? 226.038 213.502 293.605 1.00 76.82  ? 136 GLU B CA  1 
ATOM   7182  C  C   . GLU B 1 136 ? 226.348 214.241 292.313 1.00 76.82  ? 136 GLU B C   1 
ATOM   7183  O  O   . GLU B 1 136 ? 225.446 214.543 291.524 1.00 76.82  ? 136 GLU B O   1 
ATOM   7184  C  CB  . GLU B 1 136 ? 226.143 214.443 294.802 1.00 76.82  ? 136 GLU B CB  1 
ATOM   7185  C  CG  . GLU B 1 136 ? 225.361 215.732 294.640 1.00 76.82  ? 136 GLU B CG  1 
ATOM   7186  C  CD  . GLU B 1 136 ? 223.865 215.508 294.634 1.00 76.82  ? 136 GLU B CD  1 
ATOM   7187  O  OE1 . GLU B 1 136 ? 223.411 214.513 295.235 1.00 76.82  ? 136 GLU B OE1 1 
ATOM   7188  O  OE2 . GLU B 1 136 ? 223.141 216.327 294.030 1.00 76.82  ? 136 GLU B OE2 1 
ATOM   7189  N  N   . MET B 1 137 ? 227.629 214.529 292.071 1.00 80.87  ? 137 MET B N   1 
ATOM   7190  C  CA  . MET B 1 137 ? 228.012 215.203 290.835 1.00 80.87  ? 137 MET B CA  1 
ATOM   7191  C  C   . MET B 1 137 ? 227.773 214.321 289.619 1.00 80.87  ? 137 MET B C   1 
ATOM   7192  O  O   . MET B 1 137 ? 227.384 214.823 288.556 1.00 80.87  ? 137 MET B O   1 
ATOM   7193  C  CB  . MET B 1 137 ? 229.476 215.633 290.902 1.00 80.87  ? 137 MET B CB  1 
ATOM   7194  C  CG  . MET B 1 137 ? 229.838 216.744 289.931 1.00 80.87  ? 137 MET B CG  1 
ATOM   7195  S  SD  . MET B 1 137 ? 229.082 218.325 290.349 1.00 80.87  ? 137 MET B SD  1 
ATOM   7196  C  CE  . MET B 1 137 ? 229.244 218.321 292.131 1.00 80.87  ? 137 MET B CE  1 
ATOM   7197  N  N   . ALA B 1 138 ? 228.009 213.017 289.748 1.00 67.55  ? 138 ALA B N   1 
ATOM   7198  C  CA  . ALA B 1 138 ? 227.743 212.112 288.641 1.00 67.55  ? 138 ALA B CA  1 
ATOM   7199  C  C   . ALA B 1 138 ? 226.270 212.142 288.269 1.00 67.55  ? 138 ALA B C   1 
ATOM   7200  O  O   . ALA B 1 138 ? 225.913 212.236 287.089 1.00 67.55  ? 138 ALA B O   1 
ATOM   7201  C  CB  . ALA B 1 138 ? 228.185 210.698 289.006 1.00 67.55  ? 138 ALA B CB  1 
ATOM   7202  N  N   . GLN B 1 139 ? 225.396 212.097 289.272 1.00 60.69  ? 139 GLN B N   1 
ATOM   7203  C  CA  . GLN B 1 139 ? 223.969 212.165 289.004 1.00 60.69  ? 139 GLN B CA  1 
ATOM   7204  C  C   . GLN B 1 139 ? 223.569 213.525 288.452 1.00 60.69  ? 139 GLN B C   1 
ATOM   7205  O  O   . GLN B 1 139 ? 222.665 213.610 287.615 1.00 60.69  ? 139 GLN B O   1 
ATOM   7206  C  CB  . GLN B 1 139 ? 223.185 211.847 290.270 1.00 60.69  ? 139 GLN B CB  1 
ATOM   7207  C  CG  . GLN B 1 139 ? 221.701 211.768 290.043 1.00 60.69  ? 139 GLN B CG  1 
ATOM   7208  C  CD  . GLN B 1 139 ? 221.350 210.845 288.904 1.00 60.69  ? 139 GLN B CD  1 
ATOM   7209  O  OE1 . GLN B 1 139 ? 221.030 211.293 287.805 1.00 60.69  ? 139 GLN B OE1 1 
ATOM   7210  N  NE2 . GLN B 1 139 ? 221.411 209.545 289.156 1.00 60.69  ? 139 GLN B NE2 1 
ATOM   7211  N  N   . LYS B 1 140 ? 224.226 214.595 288.898 1.00 58.05  ? 140 LYS B N   1 
ATOM   7212  C  CA  . LYS B 1 140 ? 223.917 215.920 288.372 1.00 58.05  ? 140 LYS B CA  1 
ATOM   7213  C  C   . LYS B 1 140 ? 224.218 215.998 286.882 1.00 58.05  ? 140 LYS B C   1 
ATOM   7214  O  O   . LYS B 1 140 ? 223.384 216.445 286.080 1.00 58.05  ? 140 LYS B O   1 
ATOM   7215  C  CB  . LYS B 1 140 ? 224.711 216.972 289.139 1.00 58.05  ? 140 LYS B CB  1 
ATOM   7216  C  CG  . LYS B 1 140 ? 224.076 218.345 289.148 1.00 58.05  ? 140 LYS B CG  1 
ATOM   7217  C  CD  . LYS B 1 140 ? 224.990 219.368 289.806 1.00 58.05  ? 140 LYS B CD  1 
ATOM   7218  C  CE  . LYS B 1 140 ? 225.088 219.144 291.305 1.00 58.05  ? 140 LYS B CE  1 
ATOM   7219  N  NZ  . LYS B 1 140 ? 223.845 219.562 292.005 1.00 58.05  ? 140 LYS B NZ  1 
ATOM   7220  N  N   . GLU B 1 141 ? 225.414 215.561 286.492 1.00 56.79  ? 141 GLU B N   1 
ATOM   7221  C  CA  . GLU B 1 141 ? 225.766 215.545 285.078 1.00 56.79  ? 141 GLU B CA  1 
ATOM   7222  C  C   . GLU B 1 141 ? 224.842 214.622 284.300 1.00 56.79  ? 141 GLU B C   1 
ATOM   7223  O  O   . GLU B 1 141 ? 224.490 214.906 283.147 1.00 56.79  ? 141 GLU B O   1 
ATOM   7224  C  CB  . GLU B 1 141 ? 227.218 215.117 284.905 1.00 56.79  ? 141 GLU B CB  1 
ATOM   7225  C  CG  . GLU B 1 141 ? 228.213 216.235 285.116 1.00 56.79  ? 141 GLU B CG  1 
ATOM   7226  C  CD  . GLU B 1 141 ? 227.770 217.530 284.474 1.00 56.79  ? 141 GLU B CD  1 
ATOM   7227  O  OE1 . GLU B 1 141 ? 227.796 217.615 283.229 1.00 56.79  ? 141 GLU B OE1 1 
ATOM   7228  O  OE2 . GLU B 1 141 ? 227.396 218.464 285.213 1.00 56.79  ? 141 GLU B OE2 1 
ATOM   7229  N  N   . GLN B 1 142 ? 224.444 213.508 284.913 1.00 55.48  ? 142 GLN B N   1 
ATOM   7230  C  CA  . GLN B 1 142 ? 223.500 212.607 284.266 1.00 55.48  ? 142 GLN B CA  1 
ATOM   7231  C  C   . GLN B 1 142 ? 222.195 213.326 283.960 1.00 55.48  ? 142 GLN B C   1 
ATOM   7232  O  O   . GLN B 1 142 ? 221.652 213.214 282.855 1.00 55.48  ? 142 GLN B O   1 
ATOM   7233  C  CB  . GLN B 1 142 ? 223.254 211.393 285.159 1.00 55.48  ? 142 GLN B CB  1 
ATOM   7234  C  CG  . GLN B 1 142 ? 222.295 210.377 284.587 1.00 55.48  ? 142 GLN B CG  1 
ATOM   7235  C  CD  . GLN B 1 142 ? 222.866 209.647 283.393 1.00 55.48  ? 142 GLN B CD  1 
ATOM   7236  O  OE1 . GLN B 1 142 ? 222.163 209.382 282.419 1.00 55.48  ? 142 GLN B OE1 1 
ATOM   7237  N  NE2 . GLN B 1 142 ? 224.150 209.315 283.462 1.00 55.48  ? 142 GLN B NE2 1 
ATOM   7238  N  N   . THR B 1 143 ? 221.688 214.087 284.929 1.00 54.72  ? 143 THR B N   1 
ATOM   7239  C  CA  . THR B 1 143 ? 220.437 214.808 284.726 1.00 54.72  ? 143 THR B CA  1 
ATOM   7240  C  C   . THR B 1 143 ? 220.577 215.854 283.635 1.00 54.72  ? 143 THR B C   1 
ATOM   7241  O  O   . THR B 1 143 ? 219.656 216.054 282.837 1.00 54.72  ? 143 THR B O   1 
ATOM   7242  C  CB  . THR B 1 143 ? 219.985 215.460 286.028 1.00 54.72  ? 143 THR B CB  1 
ATOM   7243  O  OG1 . THR B 1 143 ? 221.091 216.143 286.625 1.00 54.72  ? 143 THR B OG1 1 
ATOM   7244  C  CG2 . THR B 1 143 ? 219.470 214.405 286.987 1.00 54.72  ? 143 THR B CG2 1 
ATOM   7245  N  N   . ARG B 1 144 ? 221.720 216.541 283.590 1.00 52.79  ? 144 ARG B N   1 
ATOM   7246  C  CA  . ARG B 1 144 ? 221.927 217.555 282.554 1.00 52.79  ? 144 ARG B CA  1 
ATOM   7247  C  C   . ARG B 1 144 ? 221.937 216.931 281.161 1.00 52.79  ? 144 ARG B C   1 
ATOM   7248  O  O   . ARG B 1 144 ? 221.285 217.427 280.229 1.00 52.79  ? 144 ARG B O   1 
ATOM   7249  C  CB  . ARG B 1 144 ? 223.226 218.309 282.814 1.00 52.79  ? 144 ARG B CB  1 
ATOM   7250  C  CG  . ARG B 1 144 ? 223.393 219.546 281.978 1.00 52.79  ? 144 ARG B CG  1 
ATOM   7251  C  CD  . ARG B 1 144 ? 224.658 220.271 282.357 1.00 52.79  ? 144 ARG B CD  1 
ATOM   7252  N  NE  . ARG B 1 144 ? 225.830 219.422 282.202 1.00 52.79  ? 144 ARG B NE  1 
ATOM   7253  C  CZ  . ARG B 1 144 ? 226.465 219.229 281.056 1.00 52.79  ? 144 ARG B CZ  1 
ATOM   7254  N  NH1 . ARG B 1 144 ? 226.070 219.817 279.940 1.00 52.79  ? 144 ARG B NH1 1 
ATOM   7255  N  NH2 . ARG B 1 144 ? 227.525 218.428 281.029 1.00 52.79  ? 144 ARG B NH2 1 
ATOM   7256  N  N   . GLN B 1 145 ? 222.677 215.837 280.996 1.00 47.80  ? 145 GLN B N   1 
ATOM   7257  C  CA  . GLN B 1 145 ? 222.711 215.188 279.694 1.00 47.80  ? 145 GLN B CA  1 
ATOM   7258  C  C   . GLN B 1 145 ? 221.346 214.634 279.324 1.00 47.80  ? 145 GLN B C   1 
ATOM   7259  O  O   . GLN B 1 145 ? 220.949 214.679 278.151 1.00 47.80  ? 145 GLN B O   1 
ATOM   7260  C  CB  . GLN B 1 145 ? 223.786 214.109 279.690 1.00 47.80  ? 145 GLN B CB  1 
ATOM   7261  C  CG  . GLN B 1 145 ? 225.176 214.687 279.464 1.00 47.80  ? 145 GLN B CG  1 
ATOM   7262  C  CD  . GLN B 1 145 ? 226.288 213.898 280.127 1.00 47.80  ? 145 GLN B CD  1 
ATOM   7263  O  OE1 . GLN B 1 145 ? 226.048 213.099 281.028 1.00 47.80  ? 145 GLN B OE1 1 
ATOM   7264  N  NE2 . GLN B 1 145 ? 227.520 214.140 279.694 1.00 47.80  ? 145 GLN B NE2 1 
ATOM   7265  N  N   . LEU B 1 146 ? 220.588 214.162 280.313 1.00 49.47  ? 146 LEU B N   1 
ATOM   7266  C  CA  . LEU B 1 146 ? 219.245 213.675 280.034 1.00 49.47  ? 146 LEU B CA  1 
ATOM   7267  C  C   . LEU B 1 146 ? 218.320 214.799 279.595 1.00 49.47  ? 146 LEU B C   1 
ATOM   7268  O  O   . LEU B 1 146 ? 217.482 214.596 278.712 1.00 49.47  ? 146 LEU B O   1 
ATOM   7269  C  CB  . LEU B 1 146 ? 218.678 212.955 281.254 1.00 49.47  ? 146 LEU B CB  1 
ATOM   7270  C  CG  . LEU B 1 146 ? 219.222 211.543 281.450 1.00 49.47  ? 146 LEU B CG  1 
ATOM   7271  C  CD1 . LEU B 1 146 ? 218.750 210.955 282.757 1.00 49.47  ? 146 LEU B CD1 1 
ATOM   7272  C  CD2 . LEU B 1 146 ? 218.787 210.672 280.291 1.00 49.47  ? 146 LEU B CD2 1 
ATOM   7273  N  N   . ILE B 1 147 ? 218.428 215.983 280.202 1.00 50.81  ? 147 ILE B N   1 
ATOM   7274  C  CA  . ILE B 1 147 ? 217.530 217.058 279.788 1.00 50.81  ? 147 ILE B CA  1 
ATOM   7275  C  C   . ILE B 1 147 ? 217.889 217.533 278.389 1.00 50.81  ? 147 ILE B C   1 
ATOM   7276  O  O   . ILE B 1 147 ? 217.006 217.883 277.597 1.00 50.81  ? 147 ILE B O   1 
ATOM   7277  C  CB  . ILE B 1 147 ? 217.501 218.219 280.803 1.00 50.81  ? 147 ILE B CB  1 
ATOM   7278  C  CG1 . ILE B 1 147 ? 218.846 218.916 280.922 1.00 50.81  ? 147 ILE B CG1 1 
ATOM   7279  C  CG2 . ILE B 1 147 ? 217.031 217.737 282.164 1.00 50.81  ? 147 ILE B CG2 1 
ATOM   7280  C  CD1 . ILE B 1 147 ? 218.811 220.131 281.812 1.00 50.81  ? 147 ILE B CD1 1 
ATOM   7281  N  N   . ILE B 1 148 ? 219.179 217.525 278.045 1.00 47.58  ? 148 ILE B N   1 
ATOM   7282  C  CA  . ILE B 1 148 ? 219.555 217.856 276.670 1.00 47.58  ? 148 ILE B CA  1 
ATOM   7283  C  C   . ILE B 1 148 ? 218.956 216.842 275.698 1.00 47.58  ? 148 ILE B C   1 
ATOM   7284  O  O   . ILE B 1 148 ? 218.411 217.204 274.644 1.00 47.58  ? 148 ILE B O   1 
ATOM   7285  C  CB  . ILE B 1 148 ? 221.084 217.943 276.527 1.00 47.58  ? 148 ILE B CB  1 
ATOM   7286  C  CG1 . ILE B 1 148 ? 221.645 219.039 277.420 1.00 47.58  ? 148 ILE B CG1 1 
ATOM   7287  C  CG2 . ILE B 1 148 ? 221.461 218.269 275.114 1.00 47.58  ? 148 ILE B CG2 1 
ATOM   7288  C  CD1 . ILE B 1 148 ? 223.146 219.030 277.490 1.00 47.58  ? 148 ILE B CD1 1 
ATOM   7289  N  N   . ALA B 1 149 ? 219.035 215.554 276.044 1.00 47.73  ? 149 ALA B N   1 
ATOM   7290  C  CA  . ALA B 1 149 ? 218.477 214.526 275.173 1.00 47.73  ? 149 ALA B CA  1 
ATOM   7291  C  C   . ALA B 1 149 ? 216.969 214.672 275.032 1.00 47.73  ? 149 ALA B C   1 
ATOM   7292  O  O   . ALA B 1 149 ? 216.422 214.515 273.935 1.00 47.73  ? 149 ALA B O   1 
ATOM   7293  C  CB  . ALA B 1 149 ? 218.830 213.140 275.699 1.00 47.73  ? 149 ALA B CB  1 
ATOM   7294  N  N   . VAL B 1 150 ? 216.279 214.968 276.135 1.00 50.72  ? 150 VAL B N   1 
ATOM   7295  C  CA  . VAL B 1 150 ? 214.828 215.130 276.099 1.00 50.72  ? 150 VAL B CA  1 
ATOM   7296  C  C   . VAL B 1 150 ? 214.445 216.339 275.262 1.00 50.72  ? 150 VAL B C   1 
ATOM   7297  O  O   . VAL B 1 150 ? 213.430 216.321 274.557 1.00 50.72  ? 150 VAL B O   1 
ATOM   7298  C  CB  . VAL B 1 150 ? 214.273 215.229 277.533 1.00 50.72  ? 150 VAL B CB  1 
ATOM   7299  C  CG1 . VAL B 1 150 ? 212.860 215.764 277.528 1.00 50.72  ? 150 VAL B CG1 1 
ATOM   7300  C  CG2 . VAL B 1 150 ? 214.320 213.873 278.206 1.00 50.72  ? 150 VAL B CG2 1 
ATOM   7301  N  N   . ASP B 1 151 ? 215.245 217.404 275.318 1.00 52.19  ? 151 ASP B N   1 
ATOM   7302  C  CA  . ASP B 1 151 ? 214.980 218.568 274.482 1.00 52.19  ? 151 ASP B CA  1 
ATOM   7303  C  C   . ASP B 1 151 ? 215.139 218.238 273.004 1.00 52.19  ? 151 ASP B C   1 
ATOM   7304  O  O   . ASP B 1 151 ? 214.310 218.637 272.179 1.00 52.19  ? 151 ASP B O   1 
ATOM   7305  C  CB  . ASP B 1 151 ? 215.901 219.715 274.884 1.00 52.19  ? 151 ASP B CB  1 
ATOM   7306  C  CG  . ASP B 1 151 ? 215.575 220.264 276.254 1.00 52.19  ? 151 ASP B CG  1 
ATOM   7307  O  OD1 . ASP B 1 151 ? 214.432 220.065 276.718 1.00 52.19  ? 151 ASP B OD1 1 
ATOM   7308  O  OD2 . ASP B 1 151 ? 216.460 220.893 276.870 1.00 52.19  ? 151 ASP B OD2 1 
ATOM   7309  N  N   . HIS B 1 152 ? 216.191 217.500 272.646 1.00 48.05  ? 152 HIS B N   1 
ATOM   7310  C  CA  . HIS B 1 152 ? 216.394 217.112 271.246 1.00 48.05  ? 152 HIS B CA  1 
ATOM   7311  C  C   . HIS B 1 152 ? 215.655 215.806 270.960 1.00 48.05  ? 152 HIS B C   1 
ATOM   7312  O  O   . HIS B 1 152 ? 216.246 214.742 270.769 1.00 48.05  ? 152 HIS B O   1 
ATOM   7313  C  CB  . HIS B 1 152 ? 217.874 216.981 270.929 1.00 48.05  ? 152 HIS B CB  1 
ATOM   7314  C  CG  . HIS B 1 152 ? 218.623 218.270 270.999 1.00 48.05  ? 152 HIS B CG  1 
ATOM   7315  N  ND1 . HIS B 1 152 ? 219.155 218.756 272.171 1.00 48.05  ? 152 HIS B ND1 1 
ATOM   7316  C  CD2 . HIS B 1 152 ? 218.936 219.171 270.040 1.00 48.05  ? 152 HIS B CD2 1 
ATOM   7317  C  CE1 . HIS B 1 152 ? 219.760 219.904 271.933 1.00 48.05  ? 152 HIS B CE1 1 
ATOM   7318  N  NE2 . HIS B 1 152 ? 219.644 220.178 270.647 1.00 48.05  ? 152 HIS B NE2 1 
ATOM   7319  N  N   . LEU B 1 153 ? 214.328 215.901 270.919 1.00 48.12  ? 153 LEU B N   1 
ATOM   7320  C  CA  . LEU B 1 153 ? 213.516 214.701 270.798 1.00 48.12  ? 153 LEU B CA  1 
ATOM   7321  C  C   . LEU B 1 153 ? 212.412 214.809 269.759 1.00 48.12  ? 153 LEU B C   1 
ATOM   7322  O  O   . LEU B 1 153 ? 211.767 213.797 269.469 1.00 48.12  ? 153 LEU B O   1 
ATOM   7323  C  CB  . LEU B 1 153 ? 212.910 214.335 272.160 1.00 48.12  ? 153 LEU B CB  1 
ATOM   7324  C  CG  . LEU B 1 153 ? 212.656 212.856 272.437 1.00 48.12  ? 153 LEU B CG  1 
ATOM   7325  C  CD1 . LEU B 1 153 ? 213.948 212.081 272.396 1.00 48.12  ? 153 LEU B CD1 1 
ATOM   7326  C  CD2 . LEU B 1 153 ? 211.985 212.681 273.777 1.00 48.12  ? 153 LEU B CD2 1 
ATOM   7327  N  N   . ASP B 1 154 ? 212.165 215.991 269.204 1.00 50.04  ? 154 ASP B N   1 
ATOM   7328  C  CA  . ASP B 1 154 ? 211.319 216.207 268.036 1.00 50.04  ? 154 ASP B CA  1 
ATOM   7329  C  C   . ASP B 1 154 ? 209.852 215.887 268.272 1.00 50.04  ? 154 ASP B C   1 
ATOM   7330  O  O   . ASP B 1 154 ? 209.102 215.741 267.303 1.00 50.04  ? 154 ASP B O   1 
ATOM   7331  C  CB  . ASP B 1 154 ? 211.816 215.408 266.827 1.00 50.04  ? 154 ASP B CB  1 
ATOM   7332  C  CG  . ASP B 1 154 ? 212.900 216.134 266.054 1.00 50.04  ? 154 ASP B CG  1 
ATOM   7333  O  OD1 . ASP B 1 154 ? 213.216 217.288 266.412 1.00 50.04  ? 154 ASP B OD1 1 
ATOM   7334  O  OD2 . ASP B 1 154 ? 213.437 215.550 265.089 1.00 50.04  ? 154 ASP B OD2 1 
ATOM   7335  N  N   . ARG B 1 155 ? 209.409 215.791 269.527 1.00 54.43  ? 155 ARG B N   1 
ATOM   7336  C  CA  . ARG B 1 155 ? 207.998 215.566 269.797 1.00 54.43  ? 155 ARG B CA  1 
ATOM   7337  C  C   . ARG B 1 155 ? 207.731 215.880 271.257 1.00 54.43  ? 155 ARG B C   1 
ATOM   7338  O  O   . ARG B 1 155 ? 208.502 215.436 272.118 1.00 54.43  ? 155 ARG B O   1 
ATOM   7339  C  CB  . ARG B 1 155 ? 207.599 214.123 269.474 1.00 54.43  ? 155 ARG B CB  1 
ATOM   7340  C  CG  . ARG B 1 155 ? 206.109 213.880 269.462 1.00 54.43  ? 155 ARG B CG  1 
ATOM   7341  C  CD  . ARG B 1 155 ? 205.778 212.483 268.981 1.00 54.43  ? 155 ARG B CD  1 
ATOM   7342  N  NE  . ARG B 1 155 ? 204.343 212.237 269.027 1.00 54.43  ? 155 ARG B NE  1 
ATOM   7343  C  CZ  . ARG B 1 155 ? 203.766 211.094 268.684 1.00 54.43  ? 155 ARG B CZ  1 
ATOM   7344  N  NH1 . ARG B 1 155 ? 204.477 210.059 268.269 1.00 54.43  ? 155 ARG B NH1 1 
ATOM   7345  N  NH2 . ARG B 1 155 ? 202.443 210.987 268.761 1.00 54.43  ? 155 ARG B NH2 1 
ATOM   7346  N  N   . PRO B 1 156 ? 206.684 216.641 271.575 1.00 52.08  ? 156 PRO B N   1 
ATOM   7347  C  CA  . PRO B 1 156 ? 206.440 217.024 272.968 1.00 52.08  ? 156 PRO B CA  1 
ATOM   7348  C  C   . PRO B 1 156 ? 206.217 215.817 273.862 1.00 52.08  ? 156 PRO B C   1 
ATOM   7349  O  O   . PRO B 1 156 ? 205.599 214.828 273.468 1.00 52.08  ? 156 PRO B O   1 
ATOM   7350  C  CB  . PRO B 1 156 ? 205.180 217.884 272.880 1.00 52.08  ? 156 PRO B CB  1 
ATOM   7351  C  CG  . PRO B 1 156 ? 205.169 218.385 271.493 1.00 52.08  ? 156 PRO B CG  1 
ATOM   7352  C  CD  . PRO B 1 156 ? 205.745 217.294 270.655 1.00 52.08  ? 156 PRO B CD  1 
ATOM   7353  N  N   . VAL B 1 157 ? 206.728 215.912 275.084 1.00 53.81  ? 157 VAL B N   1 
ATOM   7354  C  CA  . VAL B 1 157 ? 206.619 214.841 276.067 1.00 53.81  ? 157 VAL B CA  1 
ATOM   7355  C  C   . VAL B 1 157 ? 206.296 215.464 277.415 1.00 53.81  ? 157 VAL B C   1 
ATOM   7356  O  O   . VAL B 1 157 ? 206.911 216.461 277.807 1.00 53.81  ? 157 VAL B O   1 
ATOM   7357  C  CB  . VAL B 1 157 ? 207.919 214.026 276.170 1.00 53.81  ? 157 VAL B CB  1 
ATOM   7358  C  CG1 . VAL B 1 157 ? 207.782 212.956 277.220 1.00 53.81  ? 157 VAL B CG1 1 
ATOM   7359  C  CG2 . VAL B 1 157 ? 208.296 213.443 274.833 1.00 53.81  ? 157 VAL B CG2 1 
ATOM   7360  N  N   . ILE B 1 158 ? 205.343 214.876 278.132 1.00 59.91  ? 158 ILE B N   1 
ATOM   7361  C  CA  . ILE B 1 158 ? 204.981 215.311 279.475 1.00 59.91  ? 158 ILE B CA  1 
ATOM   7362  C  C   . ILE B 1 158 ? 204.927 214.093 280.380 1.00 59.91  ? 158 ILE B C   1 
ATOM   7363  O  O   . ILE B 1 158 ? 204.361 213.060 280.010 1.00 59.91  ? 158 ILE B O   1 
ATOM   7364  C  CB  . ILE B 1 158 ? 203.633 216.053 279.477 1.00 59.91  ? 158 ILE B CB  1 
ATOM   7365  C  CG1 . ILE B 1 158 ? 203.806 217.448 278.893 1.00 59.91  ? 158 ILE B CG1 1 
ATOM   7366  C  CG2 . ILE B 1 158 ? 203.069 216.143 280.865 1.00 59.91  ? 158 ILE B CG2 1 
ATOM   7367  C  CD1 . ILE B 1 158 ? 204.880 218.243 279.571 1.00 59.91  ? 158 ILE B CD1 1 
ATOM   7368  N  N   . VAL B 1 159 ? 205.515 214.215 281.563 1.00 65.31  ? 159 VAL B N   1 
ATOM   7369  C  CA  . VAL B 1 159 ? 205.501 213.162 282.569 1.00 65.31  ? 159 VAL B CA  1 
ATOM   7370  C  C   . VAL B 1 159 ? 204.565 213.598 283.689 1.00 65.31  ? 159 VAL B C   1 
ATOM   7371  O  O   . VAL B 1 159 ? 204.756 214.665 284.287 1.00 65.31  ? 159 VAL B O   1 
ATOM   7372  C  CB  . VAL B 1 159 ? 206.909 212.875 283.108 1.00 65.31  ? 159 VAL B CB  1 
ATOM   7373  C  CG1 . VAL B 1 159 ? 206.900 211.632 283.981 1.00 65.31  ? 159 VAL B CG1 1 
ATOM   7374  C  CG2 . VAL B 1 159 ? 207.888 212.715 281.961 1.00 65.31  ? 159 VAL B CG2 1 
ATOM   7375  N  N   . LEU B 1 160 ? 203.560 212.773 283.972 1.00 72.06  ? 160 LEU B N   1 
ATOM   7376  C  CA  . LEU B 1 160 ? 202.545 213.038 284.977 1.00 72.06  ? 160 LEU B CA  1 
ATOM   7377  C  C   . LEU B 1 160 ? 202.585 211.958 286.048 1.00 72.06  ? 160 LEU B C   1 
ATOM   7378  O  O   . LEU B 1 160 ? 203.062 210.847 285.819 1.00 72.06  ? 160 LEU B O   1 
ATOM   7379  C  CB  . LEU B 1 160 ? 201.155 213.099 284.344 1.00 72.06  ? 160 LEU B CB  1 
ATOM   7380  C  CG  . LEU B 1 160 ? 201.032 214.120 283.224 1.00 72.06  ? 160 LEU B CG  1 
ATOM   7381  C  CD1 . LEU B 1 160 ? 199.736 213.925 282.483 1.00 72.06  ? 160 LEU B CD1 1 
ATOM   7382  C  CD2 . LEU B 1 160 ? 201.103 215.506 283.787 1.00 72.06  ? 160 LEU B CD2 1 
ATOM   7383  N  N   . ASP B 1 161 ? 202.077 212.296 287.224 1.00 86.23  ? 161 ASP B N   1 
ATOM   7384  C  CA  . ASP B 1 161 ? 202.124 211.449 288.406 1.00 86.23  ? 161 ASP B CA  1 
ATOM   7385  C  C   . ASP B 1 161 ? 200.717 211.220 288.929 1.00 86.23  ? 161 ASP B C   1 
ATOM   7386  O  O   . ASP B 1 161 ? 199.762 211.847 288.464 1.00 86.23  ? 161 ASP B O   1 
ATOM   7387  C  CB  . ASP B 1 161 ? 203.007 212.097 289.487 1.00 86.23  ? 161 ASP B CB  1 
ATOM   7388  C  CG  . ASP B 1 161 ? 202.480 213.438 289.949 1.00 86.23  ? 161 ASP B CG  1 
ATOM   7389  O  OD1 . ASP B 1 161 ? 201.588 213.998 289.277 1.00 86.23  ? 161 ASP B OD1 1 
ATOM   7390  O  OD2 . ASP B 1 161 ? 202.970 213.938 290.983 1.00 86.23  ? 161 ASP B OD2 1 
ATOM   7391  N  N   . PRO B 1 162 ? 200.544 210.308 289.890 1.00 88.10  ? 162 PRO B N   1 
ATOM   7392  C  CA  . PRO B 1 162 ? 199.212 210.124 290.474 1.00 88.10  ? 162 PRO B CA  1 
ATOM   7393  C  C   . PRO B 1 162 ? 198.675 211.396 291.110 1.00 88.10  ? 162 PRO B C   1 
ATOM   7394  O  O   . PRO B 1 162 ? 197.466 211.522 291.328 1.00 88.10  ? 162 PRO B O   1 
ATOM   7395  C  CB  . PRO B 1 162 ? 199.440 209.019 291.508 1.00 88.10  ? 162 PRO B CB  1 
ATOM   7396  C  CG  . PRO B 1 162 ? 200.538 208.228 290.931 1.00 88.10  ? 162 PRO B CG  1 
ATOM   7397  C  CD  . PRO B 1 162 ? 201.454 209.219 290.286 1.00 88.10  ? 162 PRO B CD  1 
ATOM   7398  N  N   . GLU B 1 163 ? 199.562 212.339 291.430 1.00 95.74  ? 163 GLU B N   1 
ATOM   7399  C  CA  . GLU B 1 163 ? 199.123 213.683 291.780 1.00 95.74  ? 163 GLU B CA  1 
ATOM   7400  C  C   . GLU B 1 163 ? 198.627 214.460 290.569 1.00 95.74  ? 163 GLU B C   1 
ATOM   7401  O  O   . GLU B 1 163 ? 197.946 215.477 290.743 1.00 95.74  ? 163 GLU B O   1 
ATOM   7402  C  CB  . GLU B 1 163 ? 200.254 214.454 292.465 1.00 95.74  ? 163 GLU B CB  1 
ATOM   7403  C  CG  . GLU B 1 163 ? 200.743 213.824 293.759 1.00 95.74  ? 163 GLU B CG  1 
ATOM   7404  C  CD  . GLU B 1 163 ? 199.664 213.761 294.823 1.00 95.74  ? 163 GLU B CD  1 
ATOM   7405  O  OE1 . GLU B 1 163 ? 198.828 214.687 294.881 1.00 95.74  ? 163 GLU B OE1 1 
ATOM   7406  O  OE2 . GLU B 1 163 ? 199.653 212.785 295.602 1.00 95.74  ? 163 GLU B OE2 1 
ATOM   7407  N  N   . ARG B 1 164 ? 198.961 214.006 289.355 1.00 94.09  ? 164 ARG B N   1 
ATOM   7408  C  CA  . ARG B 1 164 ? 198.364 214.503 288.112 1.00 94.09  ? 164 ARG B CA  1 
ATOM   7409  C  C   . ARG B 1 164 ? 198.662 215.986 287.903 1.00 94.09  ? 164 ARG B C   1 
ATOM   7410  O  O   . ARG B 1 164 ? 197.767 216.802 287.685 1.00 94.09  ? 164 ARG B O   1 
ATOM   7411  C  CB  . ARG B 1 164 ? 196.864 214.216 288.092 1.00 94.09  ? 164 ARG B CB  1 
ATOM   7412  C  CG  . ARG B 1 164 ? 196.556 212.815 288.587 1.00 94.09  ? 164 ARG B CG  1 
ATOM   7413  C  CD  . ARG B 1 164 ? 195.088 212.510 288.540 1.00 94.09  ? 164 ARG B CD  1 
ATOM   7414  N  NE  . ARG B 1 164 ? 194.585 212.590 287.177 1.00 94.09  ? 164 ARG B NE  1 
ATOM   7415  C  CZ  . ARG B 1 164 ? 193.355 212.254 286.820 1.00 94.09  ? 164 ARG B CZ  1 
ATOM   7416  N  NH1 . ARG B 1 164 ? 192.484 211.791 287.701 1.00 94.09  ? 164 ARG B NH1 1 
ATOM   7417  N  NH2 . ARG B 1 164 ? 192.994 212.381 285.546 1.00 94.09  ? 164 ARG B NH2 1 
ATOM   7418  N  N   . HIS B 1 165 ? 199.942 216.326 287.987 1.00 90.83  ? 165 HIS B N   1 
ATOM   7419  C  CA  . HIS B 1 165 ? 200.440 217.649 287.660 1.00 90.83  ? 165 HIS B CA  1 
ATOM   7420  C  C   . HIS B 1 165 ? 201.577 217.505 286.660 1.00 90.83  ? 165 HIS B C   1 
ATOM   7421  O  O   . HIS B 1 165 ? 202.313 216.515 286.675 1.00 90.83  ? 165 HIS B O   1 
ATOM   7422  C  CB  . HIS B 1 165 ? 200.928 218.395 288.907 1.00 90.83  ? 165 HIS B CB  1 
ATOM   7423  C  CG  . HIS B 1 165 ? 199.912 218.470 290.002 1.00 90.83  ? 165 HIS B CG  1 
ATOM   7424  N  ND1 . HIS B 1 165 ? 198.555 218.471 289.759 1.00 90.83  ? 165 HIS B ND1 1 
ATOM   7425  C  CD2 . HIS B 1 165 ? 200.053 218.547 291.346 1.00 90.83  ? 165 HIS B CD2 1 
ATOM   7426  C  CE1 . HIS B 1 165 ? 197.904 218.546 290.906 1.00 90.83  ? 165 HIS B CE1 1 
ATOM   7427  N  NE2 . HIS B 1 165 ? 198.790 218.593 291.885 1.00 90.83  ? 165 HIS B NE2 1 
ATOM   7428  N  N   . ILE B 1 166 ? 201.708 218.493 285.779 1.00 79.62  ? 166 ILE B N   1 
ATOM   7429  C  CA  . ILE B 1 166 ? 202.783 218.491 284.795 1.00 79.62  ? 166 ILE B CA  1 
ATOM   7430  C  C   . ILE B 1 166 ? 204.099 218.662 285.537 1.00 79.62  ? 166 ILE B C   1 
ATOM   7431  O  O   . ILE B 1 166 ? 204.389 219.741 286.065 1.00 79.62  ? 166 ILE B O   1 
ATOM   7432  C  CB  . ILE B 1 166 ? 202.582 219.599 283.746 1.00 79.62  ? 166 ILE B CB  1 
ATOM   7433  C  CG1 . ILE B 1 166 ? 201.365 219.295 282.878 1.00 79.62  ? 166 ILE B CG1 1 
ATOM   7434  C  CG2 . ILE B 1 166 ? 203.823 219.749 282.889 1.00 79.62  ? 166 ILE B CG2 1 
ATOM   7435  C  CD1 . ILE B 1 166 ? 201.053 220.375 281.876 1.00 79.62  ? 166 ILE B CD1 1 
ATOM   7436  N  N   . VAL B 1 167 ? 204.903 217.603 285.592 1.00 69.57  ? 167 VAL B N   1 
ATOM   7437  C  CA  . VAL B 1 167 ? 206.145 217.643 286.353 1.00 69.57  ? 167 VAL B CA  1 
ATOM   7438  C  C   . VAL B 1 167 ? 207.301 218.047 285.449 1.00 69.57  ? 167 VAL B C   1 
ATOM   7439  O  O   . VAL B 1 167 ? 207.938 219.084 285.664 1.00 69.57  ? 167 VAL B O   1 
ATOM   7440  C  CB  . VAL B 1 167 ? 206.430 216.292 287.027 1.00 69.57  ? 167 VAL B CB  1 
ATOM   7441  C  CG1 . VAL B 1 167 ? 207.547 216.446 288.039 1.00 69.57  ? 167 VAL B CG1 1 
ATOM   7442  C  CG2 . VAL B 1 167 ? 205.181 215.762 287.689 1.00 69.57  ? 167 VAL B CG2 1 
ATOM   7443  N  N   . GLN B 1 168 ? 207.584 217.233 284.434 1.00 64.47  ? 168 GLN B N   1 
ATOM   7444  C  CA  . GLN B 1 168 ? 208.652 217.500 283.481 1.00 64.47  ? 168 GLN B CA  1 
ATOM   7445  C  C   . GLN B 1 168 ? 208.057 217.996 282.175 1.00 64.47  ? 168 GLN B C   1 
ATOM   7446  O  O   . GLN B 1 168 ? 207.036 217.481 281.713 1.00 64.47  ? 168 GLN B O   1 
ATOM   7447  C  CB  . GLN B 1 168 ? 209.491 216.252 283.216 1.00 64.47  ? 168 GLN B CB  1 
ATOM   7448  C  CG  . GLN B 1 168 ? 210.428 215.884 284.337 1.00 64.47  ? 168 GLN B CG  1 
ATOM   7449  C  CD  . GLN B 1 168 ? 211.407 216.988 284.667 1.00 64.47  ? 168 GLN B CD  1 
ATOM   7450  O  OE1 . GLN B 1 168 ? 211.768 217.178 285.824 1.00 64.47  ? 168 GLN B OE1 1 
ATOM   7451  N  NE2 . GLN B 1 168 ? 211.855 217.713 283.648 1.00 64.47  ? 168 GLN B NE2 1 
ATOM   7452  N  N   . CYS B 1 169 ? 208.697 218.989 281.581 1.00 64.17  ? 169 CYS B N   1 
ATOM   7453  C  CA  . CYS B 1 169 ? 208.260 219.528 280.306 1.00 64.17  ? 169 CYS B CA  1 
ATOM   7454  C  C   . CYS B 1 169 ? 209.346 219.268 279.269 1.00 64.17  ? 169 CYS B C   1 
ATOM   7455  O  O   . CYS B 1 169 ? 210.330 218.570 279.528 1.00 64.17  ? 169 CYS B O   1 
ATOM   7456  C  CB  . CYS B 1 169 ? 207.939 221.016 280.421 1.00 64.17  ? 169 CYS B CB  1 
ATOM   7457  S  SG  . CYS B 1 169 ? 209.382 222.083 280.244 1.00 64.17  ? 169 CYS B SG  1 
ATOM   7458  N  N   . ASN B 1 170 ? 209.161 219.837 278.084 1.00 59.91  ? 170 ASN B N   1 
ATOM   7459  C  CA  . ASN B 1 170 ? 210.072 219.620 276.975 1.00 59.91  ? 170 ASN B CA  1 
ATOM   7460  C  C   . ASN B 1 170 ? 210.257 220.930 276.224 1.00 59.91  ? 170 ASN B C   1 
ATOM   7461  O  O   . ASN B 1 170 ? 209.412 221.824 276.286 1.00 59.91  ? 170 ASN B O   1 
ATOM   7462  C  CB  . ASN B 1 170 ? 209.534 218.535 276.041 1.00 59.91  ? 170 ASN B CB  1 
ATOM   7463  C  CG  . ASN B 1 170 ? 210.624 217.810 275.310 1.00 59.91  ? 170 ASN B CG  1 
ATOM   7464  O  OD1 . ASN B 1 170 ? 211.533 218.427 274.760 1.00 59.91  ? 170 ASN B OD1 1 
ATOM   7465  N  ND2 . ASN B 1 170 ? 210.540 216.489 275.288 1.00 59.91  ? 170 ASN B ND2 1 
ATOM   7466  N  N   . ARG B 1 171 ? 211.381 221.044 275.513 1.00 59.42  ? 171 ARG B N   1 
ATOM   7467  C  CA  . ARG B 1 171 ? 211.570 222.203 274.648 1.00 59.42  ? 171 ARG B CA  1 
ATOM   7468  C  C   . ARG B 1 171 ? 210.530 222.224 273.538 1.00 59.42  ? 171 ARG B C   1 
ATOM   7469  O  O   . ARG B 1 171 ? 210.013 223.287 273.180 1.00 59.42  ? 171 ARG B O   1 
ATOM   7470  C  CB  . ARG B 1 171 ? 212.977 222.212 274.058 1.00 59.42  ? 171 ARG B CB  1 
ATOM   7471  C  CG  . ARG B 1 171 ? 213.187 223.288 273.002 1.00 59.42  ? 171 ARG B CG  1 
ATOM   7472  C  CD  . ARG B 1 171 ? 214.652 223.648 272.838 1.00 59.42  ? 171 ARG B CD  1 
ATOM   7473  N  NE  . ARG B 1 171 ? 215.341 223.747 274.119 1.00 59.42  ? 171 ARG B NE  1 
ATOM   7474  C  CZ  . ARG B 1 171 ? 216.659 223.755 274.259 1.00 59.42  ? 171 ARG B CZ  1 
ATOM   7475  N  NH1 . ARG B 1 171 ? 217.466 223.674 273.215 1.00 59.42  ? 171 ARG B NH1 1 
ATOM   7476  N  NH2 . ARG B 1 171 ? 217.181 223.847 275.479 1.00 59.42  ? 171 ARG B NH2 1 
ATOM   7477  N  N   . ALA B 1 172 ? 210.206 221.057 272.984 1.00 61.43  ? 172 ALA B N   1 
ATOM   7478  C  CA  . ALA B 1 172 ? 209.182 220.993 271.947 1.00 61.43  ? 172 ALA B CA  1 
ATOM   7479  C  C   . ALA B 1 172 ? 207.819 221.389 272.495 1.00 61.43  ? 172 ALA B C   1 
ATOM   7480  O  O   . ALA B 1 172 ? 207.060 222.109 271.836 1.00 61.43  ? 172 ALA B O   1 
ATOM   7481  C  CB  . ALA B 1 172 ? 209.130 219.591 271.346 1.00 61.43  ? 172 ALA B CB  1 
ATOM   7482  N  N   . PHE B 1 173 ? 207.489 220.924 273.699 1.00 62.02  ? 173 PHE B N   1 
ATOM   7483  C  CA  . PHE B 1 173 ? 206.227 221.302 274.325 1.00 62.02  ? 173 PHE B CA  1 
ATOM   7484  C  C   . PHE B 1 173 ? 206.180 222.797 274.605 1.00 62.02  ? 173 PHE B C   1 
ATOM   7485  O  O   . PHE B 1 173 ? 205.146 223.442 274.398 1.00 62.02  ? 173 PHE B O   1 
ATOM   7486  C  CB  . PHE B 1 173 ? 206.035 220.484 275.599 1.00 62.02  ? 173 PHE B CB  1 
ATOM   7487  C  CG  . PHE B 1 173 ? 205.098 221.092 276.588 1.00 62.02  ? 173 PHE B CG  1 
ATOM   7488  C  CD1 . PHE B 1 173 ? 205.582 221.770 277.688 1.00 62.02  ? 173 PHE B CD1 1 
ATOM   7489  C  CD2 . PHE B 1 173 ? 203.740 220.958 276.440 1.00 62.02  ? 173 PHE B CD2 1 
ATOM   7490  C  CE1 . PHE B 1 173 ? 204.723 222.318 278.609 1.00 62.02  ? 173 PHE B CE1 1 
ATOM   7491  C  CE2 . PHE B 1 173 ? 202.879 221.501 277.354 1.00 62.02  ? 173 PHE B CE2 1 
ATOM   7492  C  CZ  . PHE B 1 173 ? 203.369 222.184 278.440 1.00 62.02  ? 173 PHE B CZ  1 
ATOM   7493  N  N   . THR B 1 174 ? 207.293 223.365 275.066 1.00 65.08  ? 174 THR B N   1 
ATOM   7494  C  CA  . THR B 1 174 ? 207.369 224.807 275.270 1.00 65.08  ? 174 THR B CA  1 
ATOM   7495  C  C   . THR B 1 174 ? 207.145 225.553 273.963 1.00 65.08  ? 174 THR B C   1 
ATOM   7496  O  O   . THR B 1 174 ? 206.402 226.540 273.915 1.00 65.08  ? 174 THR B O   1 
ATOM   7497  C  CB  . THR B 1 174 ? 208.727 225.178 275.869 1.00 65.08  ? 174 THR B CB  1 
ATOM   7498  O  OG1 . THR B 1 174 ? 208.793 224.741 277.232 1.00 65.08  ? 174 THR B OG1 1 
ATOM   7499  C  CG2 . THR B 1 174 ? 208.950 226.679 275.813 1.00 65.08  ? 174 THR B CG2 1 
ATOM   7500  N  N   . GLU B 1 175 ? 207.772 225.089 272.884 1.00 65.32  ? 175 GLU B N   1 
ATOM   7501  C  CA  . GLU B 1 175 ? 207.667 225.791 271.613 1.00 65.32  ? 175 GLU B CA  1 
ATOM   7502  C  C   . GLU B 1 175 ? 206.331 225.559 270.928 1.00 65.32  ? 175 GLU B C   1 
ATOM   7503  O  O   . GLU B 1 175 ? 205.985 226.303 270.006 1.00 65.32  ? 175 GLU B O   1 
ATOM   7504  C  CB  . GLU B 1 175 ? 208.806 225.373 270.687 1.00 65.32  ? 175 GLU B CB  1 
ATOM   7505  C  CG  . GLU B 1 175 ? 210.172 225.848 271.144 1.00 65.32  ? 175 GLU B CG  1 
ATOM   7506  C  CD  . GLU B 1 175 ? 210.188 227.317 271.513 1.00 65.32  ? 175 GLU B CD  1 
ATOM   7507  O  OE1 . GLU B 1 175 ? 209.633 228.134 270.748 1.00 65.32  ? 175 GLU B OE1 1 
ATOM   7508  O  OE2 . GLU B 1 175 ? 210.754 227.657 272.573 1.00 65.32  ? 175 GLU B OE2 1 
ATOM   7509  N  N   . MET B 1 176 ? 205.580 224.545 271.343 1.00 69.19  ? 176 MET B N   1 
ATOM   7510  C  CA  . MET B 1 176 ? 204.272 224.286 270.751 1.00 69.19  ? 176 MET B CA  1 
ATOM   7511  C  C   . MET B 1 176 ? 203.154 225.002 271.507 1.00 69.19  ? 176 MET B C   1 
ATOM   7512  O  O   . MET B 1 176 ? 202.349 225.717 270.905 1.00 69.19  ? 176 MET B O   1 
ATOM   7513  C  CB  . MET B 1 176 ? 204.012 222.777 270.707 1.00 69.19  ? 176 MET B CB  1 
ATOM   7514  C  CG  . MET B 1 176 ? 202.621 222.397 270.254 1.00 69.19  ? 176 MET B CG  1 
ATOM   7515  S  SD  . MET B 1 176 ? 202.341 220.625 270.371 1.00 69.19  ? 176 MET B SD  1 
ATOM   7516  C  CE  . MET B 1 176 ? 202.734 220.118 268.704 1.00 69.19  ? 176 MET B CE  1 
ATOM   7517  N  N   . PHE B 1 177 ? 203.091 224.819 272.827 1.00 72.25  ? 177 PHE B N   1 
ATOM   7518  C  CA  . PHE B 1 177 ? 201.994 225.368 273.609 1.00 72.25  ? 177 PHE B CA  1 
ATOM   7519  C  C   . PHE B 1 177 ? 202.348 226.638 274.365 1.00 72.25  ? 177 PHE B C   1 
ATOM   7520  O  O   . PHE B 1 177 ? 201.448 227.275 274.919 1.00 72.25  ? 177 PHE B O   1 
ATOM   7521  C  CB  . PHE B 1 177 ? 201.482 224.329 274.609 1.00 72.25  ? 177 PHE B CB  1 
ATOM   7522  C  CG  . PHE B 1 177 ? 200.887 223.122 273.967 1.00 72.25  ? 177 PHE B CG  1 
ATOM   7523  C  CD1 . PHE B 1 177 ? 199.947 223.250 272.965 1.00 72.25  ? 177 PHE B CD1 1 
ATOM   7524  C  CD2 . PHE B 1 177 ? 201.262 221.855 274.366 1.00 72.25  ? 177 PHE B CD2 1 
ATOM   7525  C  CE1 . PHE B 1 177 ? 199.395 222.136 272.371 1.00 72.25  ? 177 PHE B CE1 1 
ATOM   7526  C  CE2 . PHE B 1 177 ? 200.716 220.736 273.776 1.00 72.25  ? 177 PHE B CE2 1 
ATOM   7527  C  CZ  . PHE B 1 177 ? 199.780 220.877 272.778 1.00 72.25  ? 177 PHE B CZ  1 
ATOM   7528  N  N   . GLY B 1 178 ? 203.618 227.019 274.419 1.00 76.06  ? 178 GLY B N   1 
ATOM   7529  C  CA  . GLY B 1 178 ? 203.991 228.265 275.050 1.00 76.06  ? 178 GLY B CA  1 
ATOM   7530  C  C   . GLY B 1 178 ? 204.117 228.226 276.557 1.00 76.06  ? 178 GLY B C   1 
ATOM   7531  O  O   . GLY B 1 178 ? 204.449 229.257 277.157 1.00 76.06  ? 178 GLY B O   1 
ATOM   7532  N  N   . TYR B 1 179 ? 203.868 227.084 277.192 1.00 80.38  ? 179 TYR B N   1 
ATOM   7533  C  CA  . TYR B 1 179 ? 204.022 226.952 278.640 1.00 80.38  ? 179 TYR B CA  1 
ATOM   7534  C  C   . TYR B 1 179 ? 205.471 226.594 278.943 1.00 80.38  ? 179 TYR B C   1 
ATOM   7535  O  O   . TYR B 1 179 ? 205.936 225.503 278.606 1.00 80.38  ? 179 TYR B O   1 
ATOM   7536  C  CB  . TYR B 1 179 ? 203.084 225.885 279.190 1.00 80.38  ? 179 TYR B CB  1 
ATOM   7537  C  CG  . TYR B 1 179 ? 201.622 226.260 279.225 1.00 80.38  ? 179 TYR B CG  1 
ATOM   7538  C  CD1 . TYR B 1 179 ? 200.906 226.457 278.057 1.00 80.38  ? 179 TYR B CD1 1 
ATOM   7539  C  CD2 . TYR B 1 179 ? 200.952 226.388 280.434 1.00 80.38  ? 179 TYR B CD2 1 
ATOM   7540  C  CE1 . TYR B 1 179 ? 199.567 226.783 278.091 1.00 80.38  ? 179 TYR B CE1 1 
ATOM   7541  C  CE2 . TYR B 1 179 ? 199.617 226.716 280.480 1.00 80.38  ? 179 TYR B CE2 1 
ATOM   7542  C  CZ  . TYR B 1 179 ? 198.928 226.914 279.306 1.00 80.38  ? 179 TYR B CZ  1 
ATOM   7543  O  OH  . TYR B 1 179 ? 197.593 227.242 279.346 1.00 80.38  ? 179 TYR B OH  1 
ATOM   7544  N  N   . CYS B 1 180 ? 206.191 227.501 279.591 1.00 79.84  ? 180 CYS B N   1 
ATOM   7545  C  CA  . CYS B 1 180 ? 207.566 227.213 279.961 1.00 79.84  ? 180 CYS B CA  1 
ATOM   7546  C  C   . CYS B 1 180 ? 207.590 226.233 281.132 1.00 79.84  ? 180 CYS B C   1 
ATOM   7547  O  O   . CYS B 1 180 ? 206.551 225.817 281.653 1.00 79.84  ? 180 CYS B O   1 
ATOM   7548  C  CB  . CYS B 1 180 ? 208.307 228.503 280.303 1.00 79.84  ? 180 CYS B CB  1 
ATOM   7549  S  SG  . CYS B 1 180 ? 207.705 229.345 281.785 1.00 79.84  ? 180 CYS B SG  1 
ATOM   7550  N  N   . ILE B 1 181 ? 208.800 225.862 281.555 1.00 76.60  ? 181 ILE B N   1 
ATOM   7551  C  CA  . ILE B 1 181 ? 208.948 224.829 282.579 1.00 76.60  ? 181 ILE B CA  1 
ATOM   7552  C  C   . ILE B 1 181 ? 208.359 225.290 283.908 1.00 76.60  ? 181 ILE B C   1 
ATOM   7553  O  O   . ILE B 1 181 ? 207.546 224.587 284.524 1.00 76.60  ? 181 ILE B O   1 
ATOM   7554  C  CB  . ILE B 1 181 ? 210.426 224.422 282.722 1.00 76.60  ? 181 ILE B CB  1 
ATOM   7555  C  CG1 . ILE B 1 181 ? 210.615 223.501 283.930 1.00 76.60  ? 181 ILE B CG1 1 
ATOM   7556  C  CG2 . ILE B 1 181 ? 211.331 225.648 282.785 1.00 76.60  ? 181 ILE B CG2 1 
ATOM   7557  C  CD1 . ILE B 1 181 ? 209.887 222.178 283.818 1.00 76.60  ? 181 ILE B CD1 1 
ATOM   7558  N  N   . SER B 1 182 ? 208.747 226.483 284.366 1.00 77.81  ? 182 SER B N   1 
ATOM   7559  C  CA  . SER B 1 182 ? 208.301 226.957 285.672 1.00 77.81  ? 182 SER B CA  1 
ATOM   7560  C  C   . SER B 1 182 ? 206.794 227.153 285.697 1.00 77.81  ? 182 SER B C   1 
ATOM   7561  O  O   . SER B 1 182 ? 206.121 226.759 286.655 1.00 77.81  ? 182 SER B O   1 
ATOM   7562  C  CB  . SER B 1 182 ? 209.015 228.259 286.029 1.00 77.81  ? 182 SER B CB  1 
ATOM   7563  O  OG  . SER B 1 182 ? 208.677 229.281 285.109 1.00 77.81  ? 182 SER B OG  1 
ATOM   7564  N  N   . GLU B 1 183 ? 206.245 227.750 284.641 1.00 82.82  ? 183 GLU B N   1 
ATOM   7565  C  CA  . GLU B 1 183 ? 204.809 227.988 284.590 1.00 82.82  ? 183 GLU B CA  1 
ATOM   7566  C  C   . GLU B 1 183 ? 204.038 226.677 284.542 1.00 82.82  ? 183 GLU B C   1 
ATOM   7567  O  O   . GLU B 1 183 ? 203.094 226.471 285.313 1.00 82.82  ? 183 GLU B O   1 
ATOM   7568  C  CB  . GLU B 1 183 ? 204.471 228.859 283.381 1.00 82.82  ? 183 GLU B CB  1 
ATOM   7569  C  CG  . GLU B 1 183 ? 202.988 229.082 283.171 1.00 82.82  ? 183 GLU B CG  1 
ATOM   7570  C  CD  . GLU B 1 183 ? 202.705 230.201 282.190 1.00 82.82  ? 183 GLU B CD  1 
ATOM   7571  O  OE1 . GLU B 1 183 ? 203.668 230.723 281.589 1.00 82.82  ? 183 GLU B OE1 1 
ATOM   7572  O  OE2 . GLU B 1 183 ? 201.521 230.559 282.019 1.00 82.82  ? 183 GLU B OE2 1 
ATOM   7573  N  N   . ALA B 1 184 ? 204.435 225.767 283.649 1.00 82.56  ? 184 ALA B N   1 
ATOM   7574  C  CA  . ALA B 1 184 ? 203.703 224.517 283.496 1.00 82.56  ? 184 ALA B CA  1 
ATOM   7575  C  C   . ALA B 1 184 ? 203.906 223.577 284.674 1.00 82.56  ? 184 ALA B C   1 
ATOM   7576  O  O   . ALA B 1 184 ? 203.152 222.608 284.811 1.00 82.56  ? 184 ALA B O   1 
ATOM   7577  C  CB  . ALA B 1 184 ? 204.115 223.820 282.199 1.00 82.56  ? 184 ALA B CB  1 
ATOM   7578  N  N   . SER B 1 185 ? 204.900 223.831 285.520 1.00 82.15  ? 185 SER B N   1 
ATOM   7579  C  CA  . SER B 1 185 ? 205.151 222.948 286.649 1.00 82.15  ? 185 SER B CA  1 
ATOM   7580  C  C   . SER B 1 185 ? 203.998 222.993 287.644 1.00 82.15  ? 185 SER B C   1 
ATOM   7581  O  O   . SER B 1 185 ? 203.439 224.056 287.928 1.00 82.15  ? 185 SER B O   1 
ATOM   7582  C  CB  . SER B 1 185 ? 206.455 223.333 287.343 1.00 82.15  ? 185 SER B CB  1 
ATOM   7583  O  OG  . SER B 1 185 ? 206.818 222.364 288.309 1.00 82.15  ? 185 SER B OG  1 
ATOM   7584  N  N   . GLY B 1 186 ? 203.630 221.823 288.158 1.00 83.48  ? 186 GLY B N   1 
ATOM   7585  C  CA  . GLY B 1 186 ? 202.679 221.727 289.241 1.00 83.48  ? 186 GLY B CA  1 
ATOM   7586  C  C   . GLY B 1 186 ? 201.244 222.054 288.896 1.00 83.48  ? 186 GLY B C   1 
ATOM   7587  O  O   . GLY B 1 186 ? 200.479 222.415 289.799 1.00 83.48  ? 186 GLY B O   1 
ATOM   7588  N  N   . MET B 1 187 ? 200.849 221.949 287.633 1.00 91.19  ? 187 MET B N   1 
ATOM   7589  C  CA  . MET B 1 187 ? 199.472 222.177 287.227 1.00 91.19  ? 187 MET B CA  1 
ATOM   7590  C  C   . MET B 1 187 ? 198.909 220.927 286.565 1.00 91.19  ? 187 MET B C   1 
ATOM   7591  O  O   . MET B 1 187 ? 199.624 220.185 285.886 1.00 91.19  ? 187 MET B O   1 
ATOM   7592  C  CB  . MET B 1 187 ? 199.361 223.366 286.267 1.00 91.19  ? 187 MET B CB  1 
ATOM   7593  C  CG  . MET B 1 187 ? 199.913 223.101 284.872 1.00 91.19  ? 187 MET B CG  1 
ATOM   7594  S  SD  . MET B 1 187 ? 199.326 224.268 283.627 1.00 91.19  ? 187 MET B SD  1 
ATOM   7595  C  CE  . MET B 1 187 ? 200.192 225.757 284.117 1.00 91.19  ? 187 MET B CE  1 
ATOM   7596  N  N   . GLN B 1 188 ? 197.626 220.692 286.779 1.00 99.31  ? 188 GLN B N   1 
ATOM   7597  C  CA  . GLN B 1 188 ? 196.961 219.566 286.139 1.00 99.31  ? 188 GLN B CA  1 
ATOM   7598  C  C   . GLN B 1 188 ? 196.863 219.812 284.637 1.00 99.31  ? 188 GLN B C   1 
ATOM   7599  O  O   . GLN B 1 188 ? 196.449 220.898 284.218 1.00 99.31  ? 188 GLN B O   1 
ATOM   7600  C  CB  . GLN B 1 188 ? 195.573 219.360 286.740 1.00 99.31  ? 188 GLN B CB  1 
ATOM   7601  C  CG  . GLN B 1 188 ? 194.722 218.313 286.034 1.00 99.31  ? 188 GLN B CG  1 
ATOM   7602  C  CD  . GLN B 1 188 ? 194.972 216.908 286.542 1.00 99.31  ? 188 GLN B CD  1 
ATOM   7603  O  OE1 . GLN B 1 188 ? 195.561 216.080 285.849 1.00 99.31  ? 188 GLN B OE1 1 
ATOM   7604  N  NE2 . GLN B 1 188 ? 194.528 216.634 287.763 1.00 99.31  ? 188 GLN B NE2 1 
ATOM   7605  N  N   . PRO B 1 189 ? 197.246 218.845 283.801 1.00 98.96  ? 189 PRO B N   1 
ATOM   7606  C  CA  . PRO B 1 189 ? 197.210 219.088 282.348 1.00 98.96  ? 189 PRO B CA  1 
ATOM   7607  C  C   . PRO B 1 189 ? 195.810 219.270 281.793 1.00 98.96  ? 189 PRO B C   1 
ATOM   7608  O  O   . PRO B 1 189 ? 195.541 220.267 281.113 1.00 98.96  ? 189 PRO B O   1 
ATOM   7609  C  CB  . PRO B 1 189 ? 197.895 217.842 281.774 1.00 98.96  ? 189 PRO B CB  1 
ATOM   7610  C  CG  . PRO B 1 189 ? 197.735 216.801 282.827 1.00 98.96  ? 189 PRO B CG  1 
ATOM   7611  C  CD  . PRO B 1 189 ? 197.807 217.526 284.130 1.00 98.96  ? 189 PRO B CD  1 
ATOM   7612  N  N   . ASP B 1 190 ? 194.901 218.340 282.066 1.00 103.82 ? 190 ASP B N   1 
ATOM   7613  C  CA  . ASP B 1 190 ? 193.609 218.350 281.393 1.00 103.82 ? 190 ASP B CA  1 
ATOM   7614  C  C   . ASP B 1 190 ? 192.590 219.283 282.036 1.00 103.82 ? 190 ASP B C   1 
ATOM   7615  O  O   . ASP B 1 190 ? 191.426 219.271 281.621 1.00 103.82 ? 190 ASP B O   1 
ATOM   7616  C  CB  . ASP B 1 190 ? 193.038 216.932 281.324 1.00 103.82 ? 190 ASP B CB  1 
ATOM   7617  C  CG  . ASP B 1 190 ? 193.609 216.133 280.169 1.00 103.82 ? 190 ASP B CG  1 
ATOM   7618  O  OD1 . ASP B 1 190 ? 194.479 216.667 279.450 1.00 103.82 ? 190 ASP B OD1 1 
ATOM   7619  O  OD2 . ASP B 1 190 ? 193.177 214.980 279.969 1.00 103.82 ? 190 ASP B OD2 1 
ATOM   7620  N  N   . THR B 1 191 ? 192.981 220.087 283.026 1.00 104.77 ? 191 THR B N   1 
ATOM   7621  C  CA  . THR B 1 191 ? 192.072 221.063 283.607 1.00 104.77 ? 191 THR B CA  1 
ATOM   7622  C  C   . THR B 1 191 ? 192.545 222.503 283.483 1.00 104.77 ? 191 THR B C   1 
ATOM   7623  O  O   . THR B 1 191 ? 191.708 223.388 283.274 1.00 104.77 ? 191 THR B O   1 
ATOM   7624  C  CB  . THR B 1 191 ? 191.819 220.762 285.092 1.00 104.77 ? 191 THR B CB  1 
ATOM   7625  O  OG1 . THR B 1 191 ? 193.020 220.991 285.839 1.00 104.77 ? 191 THR B OG1 1 
ATOM   7626  C  CG2 . THR B 1 191 ? 191.363 219.327 285.276 1.00 104.77 ? 191 THR B CG2 1 
ATOM   7627  N  N   . LEU B 1 192 ? 193.847 222.772 283.602 1.00 102.85 ? 192 LEU B N   1 
ATOM   7628  C  CA  . LEU B 1 192 ? 194.331 224.140 283.516 1.00 102.85 ? 192 LEU B CA  1 
ATOM   7629  C  C   . LEU B 1 192 ? 194.745 224.550 282.112 1.00 102.85 ? 192 LEU B C   1 
ATOM   7630  O  O   . LEU B 1 192 ? 194.631 225.734 281.778 1.00 102.85 ? 192 LEU B O   1 
ATOM   7631  C  CB  . LEU B 1 192 ? 195.506 224.361 284.481 1.00 102.85 ? 192 LEU B CB  1 
ATOM   7632  C  CG  . LEU B 1 192 ? 195.868 225.832 284.703 1.00 102.85 ? 192 LEU B CG  1 
ATOM   7633  C  CD1 . LEU B 1 192 ? 194.639 226.610 285.144 1.00 102.85 ? 192 LEU B CD1 1 
ATOM   7634  C  CD2 . LEU B 1 192 ? 196.967 225.973 285.737 1.00 102.85 ? 192 LEU B CD2 1 
ATOM   7635  N  N   . LEU B 1 193 ? 195.210 223.616 281.285 1.00 99.64  ? 193 LEU B N   1 
ATOM   7636  C  CA  . LEU B 1 193 ? 195.369 223.894 279.862 1.00 99.64  ? 193 LEU B CA  1 
ATOM   7637  C  C   . LEU B 1 193 ? 194.005 224.258 279.292 1.00 99.64  ? 193 LEU B C   1 
ATOM   7638  O  O   . LEU B 1 193 ? 193.064 223.462 279.360 1.00 99.64  ? 193 LEU B O   1 
ATOM   7639  C  CB  . LEU B 1 193 ? 195.967 222.691 279.141 1.00 99.64  ? 193 LEU B CB  1 
ATOM   7640  C  CG  . LEU B 1 193 ? 197.415 222.337 279.484 1.00 99.64  ? 193 LEU B CG  1 
ATOM   7641  C  CD1 . LEU B 1 193 ? 197.839 221.064 278.768 1.00 99.64  ? 193 LEU B CD1 1 
ATOM   7642  C  CD2 . LEU B 1 193 ? 198.344 223.486 279.132 1.00 99.64  ? 193 LEU B CD2 1 
ATOM   7643  N  N   . ASN B 1 194 ? 193.895 225.464 278.741 1.00 101.12 ? 194 ASN B N   1 
ATOM   7644  C  CA  . ASN B 1 194 ? 192.593 226.018 278.399 1.00 101.12 ? 194 ASN B CA  1 
ATOM   7645  C  C   . ASN B 1 194 ? 191.879 225.172 277.352 1.00 101.12 ? 194 ASN B C   1 
ATOM   7646  O  O   . ASN B 1 194 ? 192.452 224.804 276.323 1.00 101.12 ? 194 ASN B O   1 
ATOM   7647  C  CB  . ASN B 1 194 ? 192.750 227.454 277.902 1.00 101.12 ? 194 ASN B CB  1 
ATOM   7648  C  CG  . ASN B 1 194 ? 193.529 228.322 278.870 1.00 101.12 ? 194 ASN B CG  1 
ATOM   7649  O  OD1 . ASN B 1 194 ? 194.555 228.902 278.515 1.00 101.12 ? 194 ASN B OD1 1 
ATOM   7650  N  ND2 . ASN B 1 194 ? 193.049 228.408 280.105 1.00 101.12 ? 194 ASN B ND2 1 
ATOM   7651  N  N   . THR B 1 195 ? 190.618 224.872 277.627 1.00 100.13 ? 195 THR B N   1 
ATOM   7652  C  CA  . THR B 1 195 ? 189.762 224.120 276.730 1.00 100.13 ? 195 THR B CA  1 
ATOM   7653  C  C   . THR B 1 195 ? 189.173 225.033 275.661 1.00 100.13 ? 195 THR B C   1 
ATOM   7654  O  O   . THR B 1 195 ? 189.129 226.254 275.826 1.00 100.13 ? 195 THR B O   1 
ATOM   7655  C  CB  . THR B 1 195 ? 188.639 223.459 277.524 1.00 100.13 ? 195 THR B CB  1 
ATOM   7656  O  OG1 . THR B 1 195 ? 187.752 222.766 276.640 1.00 100.13 ? 195 THR B OG1 1 
ATOM   7657  C  CG2 . THR B 1 195 ? 187.850 224.505 278.294 1.00 100.13 ? 195 THR B CG2 1 
ATOM   7658  N  N   . PRO B 1 196 ? 188.731 224.469 274.542 1.00 105.40 ? 196 PRO B N   1 
ATOM   7659  C  CA  . PRO B 1 196 ? 187.848 225.220 273.647 1.00 105.40 ? 196 PRO B CA  1 
ATOM   7660  C  C   . PRO B 1 196 ? 186.522 225.516 274.330 1.00 105.40 ? 196 PRO B C   1 
ATOM   7661  O  O   . PRO B 1 196 ? 186.179 224.939 275.364 1.00 105.40 ? 196 PRO B O   1 
ATOM   7662  C  CB  . PRO B 1 196 ? 187.660 224.278 272.451 1.00 105.40 ? 196 PRO B CB  1 
ATOM   7663  C  CG  . PRO B 1 196 ? 188.041 222.920 272.966 1.00 105.40 ? 196 PRO B CG  1 
ATOM   7664  C  CD  . PRO B 1 196 ? 189.132 223.181 273.955 1.00 105.40 ? 196 PRO B CD  1 
ATOM   7665  N  N   . GLU B 1 197 ? 185.685 226.368 273.735 1.00 112.92 ? 197 GLU B N   1 
ATOM   7666  C  CA  . GLU B 1 197 ? 184.392 226.668 274.415 1.00 112.92 ? 197 GLU B CA  1 
ATOM   7667  C  C   . GLU B 1 197 ? 183.366 225.568 274.124 1.00 112.92 ? 197 GLU B C   1 
ATOM   7668  O  O   . GLU B 1 197 ? 182.192 225.768 274.478 1.00 112.92 ? 197 GLU B O   1 
ATOM   7669  C  CB  . GLU B 1 197 ? 183.851 228.031 273.984 1.00 112.92 ? 197 GLU B CB  1 
ATOM   7670  C  CG  . GLU B 1 197 ? 183.630 228.144 272.488 1.00 112.92 ? 197 GLU B CG  1 
ATOM   7671  C  CD  . GLU B 1 197 ? 183.072 229.481 272.033 1.00 112.92 ? 197 GLU B CD  1 
ATOM   7672  O  OE1 . GLU B 1 197 ? 182.847 230.351 272.898 1.00 112.92 ? 197 GLU B OE1 1 
ATOM   7673  O  OE2 . GLU B 1 197 ? 182.863 229.650 270.816 1.00 112.92 ? 197 GLU B OE2 1 
ATOM   7674  N  N   . PHE B 1 198 ? 183.786 224.459 273.507 1.00 116.53 ? 198 PHE B N   1 
ATOM   7675  C  CA  . PHE B 1 198 ? 182.830 223.429 273.013 1.00 116.53 ? 198 PHE B CA  1 
ATOM   7676  C  C   . PHE B 1 198 ? 182.766 222.258 274.007 1.00 116.53 ? 198 PHE B C   1 
ATOM   7677  O  O   . PHE B 1 198 ? 183.517 222.290 275.000 1.00 116.53 ? 198 PHE B O   1 
ATOM   7678  C  CB  . PHE B 1 198 ? 183.231 222.983 271.604 1.00 116.53 ? 198 PHE B CB  1 
ATOM   7679  C  CG  . PHE B 1 198 ? 184.104 221.754 271.546 1.00 116.53 ? 198 PHE B CG  1 
ATOM   7680  C  CD1 . PHE B 1 198 ? 185.303 221.703 272.236 1.00 116.53 ? 198 PHE B CD1 1 
ATOM   7681  C  CD2 . PHE B 1 198 ? 183.736 220.651 270.792 1.00 116.53 ? 198 PHE B CD2 1 
ATOM   7682  C  CE1 . PHE B 1 198 ? 186.108 220.576 272.194 1.00 116.53 ? 198 PHE B CE1 1 
ATOM   7683  C  CE2 . PHE B 1 198 ? 184.544 219.526 270.741 1.00 116.53 ? 198 PHE B CE2 1 
ATOM   7684  C  CZ  . PHE B 1 198 ? 185.728 219.490 271.442 1.00 116.53 ? 198 PHE B CZ  1 
ATOM   7685  N  N   . PRO B 1 199 ? 181.912 221.228 273.801 1.00 115.20 ? 199 PRO B N   1 
ATOM   7686  C  CA  . PRO B 1 199 ? 182.041 219.959 274.521 1.00 115.20 ? 199 PRO B CA  1 
ATOM   7687  C  C   . PRO B 1 199 ? 183.113 219.031 273.944 1.00 115.20 ? 199 PRO B C   1 
ATOM   7688  O  O   . PRO B 1 199 ? 182.763 217.984 273.444 1.00 115.20 ? 199 PRO B O   1 
ATOM   7689  C  CB  . PRO B 1 199 ? 180.682 219.289 274.318 1.00 115.20 ? 199 PRO B CB  1 
ATOM   7690  C  CG  . PRO B 1 199 ? 180.207 219.827 272.986 1.00 115.20 ? 199 PRO B CG  1 
ATOM   7691  C  CD  . PRO B 1 199 ? 180.745 221.241 272.916 1.00 115.20 ? 199 PRO B CD  1 
ATOM   7692  N  N   . ALA B 1 200 ? 184.381 219.442 274.049 1.00 109.00 ? 200 ALA B N   1 
ATOM   7693  C  CA  . ALA B 1 200 ? 185.538 218.526 274.104 1.00 109.00 ? 200 ALA B CA  1 
ATOM   7694  C  C   . ALA B 1 200 ? 186.051 218.494 275.548 1.00 109.00 ? 200 ALA B C   1 
ATOM   7695  O  O   . ALA B 1 200 ? 186.920 219.311 275.881 1.00 109.00 ? 200 ALA B O   1 
ATOM   7696  C  CB  . ALA B 1 200 ? 186.579 219.008 273.140 1.00 109.00 ? 200 ALA B CB  1 
ATOM   7697  N  N   . ASP B 1 201 ? 185.479 217.616 276.379 1.00 104.43 ? 201 ASP B N   1 
ATOM   7698  C  CA  . ASP B 1 201 ? 185.729 217.584 277.845 1.00 104.43 ? 201 ASP B CA  1 
ATOM   7699  C  C   . ASP B 1 201 ? 186.977 216.752 278.151 1.00 104.43 ? 201 ASP B C   1 
ATOM   7700  O  O   . ASP B 1 201 ? 186.823 215.615 278.629 1.00 104.43 ? 201 ASP B O   1 
ATOM   7701  C  CB  . ASP B 1 201 ? 184.525 217.029 278.598 1.00 104.43 ? 201 ASP B CB  1 
ATOM   7702  C  CG  . ASP B 1 201 ? 183.876 215.833 277.925 1.00 104.43 ? 201 ASP B CG  1 
ATOM   7703  O  OD1 . ASP B 1 201 ? 184.329 215.462 276.827 1.00 104.43 ? 201 ASP B OD1 1 
ATOM   7704  O  OD2 . ASP B 1 201 ? 182.927 215.281 278.508 1.00 104.43 ? 201 ASP B OD2 1 
ATOM   7705  N  N   . ASN B 1 202 ? 188.165 217.320 277.903 1.00 100.93 ? 202 ASN B N   1 
ATOM   7706  C  CA  . ASN B 1 202 ? 189.449 216.621 277.958 1.00 100.93 ? 202 ASN B CA  1 
ATOM   7707  C  C   . ASN B 1 202 ? 189.646 215.777 279.210 1.00 100.93 ? 202 ASN B C   1 
ATOM   7708  O  O   . ASN B 1 202 ? 190.006 214.599 279.118 1.00 100.93 ? 202 ASN B O   1 
ATOM   7709  C  CB  . ASN B 1 202 ? 190.591 217.634 277.874 1.00 100.93 ? 202 ASN B CB  1 
ATOM   7710  C  CG  . ASN B 1 202 ? 190.518 218.493 276.633 1.00 100.93 ? 202 ASN B CG  1 
ATOM   7711  O  OD1 . ASN B 1 202 ? 190.666 218.004 275.515 1.00 100.93 ? 202 ASN B OD1 1 
ATOM   7712  N  ND2 . ASN B 1 202 ? 190.290 219.787 276.823 1.00 100.93 ? 202 ASN B ND2 1 
ATOM   7713  N  N   . ARG B 1 203 ? 189.429 216.372 280.384 1.00 100.49 ? 203 ARG B N   1 
ATOM   7714  C  CA  . ARG B 1 203 ? 189.624 215.631 281.624 1.00 100.49 ? 203 ARG B CA  1 
ATOM   7715  C  C   . ARG B 1 203 ? 188.661 214.457 281.720 1.00 100.49 ? 203 ARG B C   1 
ATOM   7716  O  O   . ARG B 1 203 ? 189.053 213.356 282.122 1.00 100.49 ? 203 ARG B O   1 
ATOM   7717  C  CB  . ARG B 1 203 ? 189.464 216.563 282.825 1.00 100.49 ? 203 ARG B CB  1 
ATOM   7718  C  CG  . ARG B 1 203 ? 189.566 215.865 284.173 1.00 100.49 ? 203 ARG B CG  1 
ATOM   7719  C  CD  . ARG B 1 203 ? 190.938 215.238 284.368 1.00 100.49 ? 203 ARG B CD  1 
ATOM   7720  N  NE  . ARG B 1 203 ? 191.062 214.578 285.662 1.00 100.49 ? 203 ARG B NE  1 
ATOM   7721  C  CZ  . ARG B 1 203 ? 191.422 215.190 286.782 1.00 100.49 ? 203 ARG B CZ  1 
ATOM   7722  N  NH1 . ARG B 1 203 ? 191.715 216.478 286.800 1.00 100.49 ? 203 ARG B NH1 1 
ATOM   7723  N  NH2 . ARG B 1 203 ? 191.489 214.492 287.911 1.00 100.49 ? 203 ARG B NH2 1 
ATOM   7724  N  N   . ILE B 1 204 ? 187.397 214.673 281.351 1.00 103.04 ? 204 ILE B N   1 
ATOM   7725  C  CA  . ILE B 1 204 ? 186.412 213.595 281.393 1.00 103.04 ? 204 ILE B CA  1 
ATOM   7726  C  C   . ILE B 1 204 ? 186.778 212.503 280.397 1.00 103.04 ? 204 ILE B C   1 
ATOM   7727  O  O   . ILE B 1 204 ? 186.637 211.308 280.683 1.00 103.04 ? 204 ILE B O   1 
ATOM   7728  C  CB  . ILE B 1 204 ? 185.000 214.152 281.133 1.00 103.04 ? 204 ILE B CB  1 
ATOM   7729  C  CG1 . ILE B 1 204 ? 184.678 215.269 282.128 1.00 103.04 ? 204 ILE B CG1 1 
ATOM   7730  C  CG2 . ILE B 1 204 ? 183.962 213.043 281.222 1.00 103.04 ? 204 ILE B CG2 1 
ATOM   7731  C  CD1 . ILE B 1 204 ? 183.287 215.845 281.974 1.00 103.04 ? 204 ILE B CD1 1 
ATOM   7732  N  N   . ARG B 1 205 ? 187.247 212.895 279.211 1.00 102.06 ? 205 ARG B N   1 
ATOM   7733  C  CA  . ARG B 1 205 ? 187.682 211.910 278.224 1.00 102.06 ? 205 ARG B CA  1 
ATOM   7734  C  C   . ARG B 1 205 ? 188.837 211.077 278.764 1.00 102.06 ? 205 ARG B C   1 
ATOM   7735  O  O   . ARG B 1 205 ? 188.898 209.861 278.550 1.00 102.06 ? 205 ARG B O   1 
ATOM   7736  C  CB  . ARG B 1 205 ? 188.086 212.609 276.926 1.00 102.06 ? 205 ARG B CB  1 
ATOM   7737  C  CG  . ARG B 1 205 ? 187.011 213.504 276.351 1.00 102.06 ? 205 ARG B CG  1 
ATOM   7738  C  CD  . ARG B 1 205 ? 185.762 212.711 276.007 1.00 102.06 ? 205 ARG B CD  1 
ATOM   7739  N  NE  . ARG B 1 205 ? 185.994 211.745 274.941 1.00 102.06 ? 205 ARG B NE  1 
ATOM   7740  C  CZ  . ARG B 1 205 ? 186.061 212.055 273.653 1.00 102.06 ? 205 ARG B CZ  1 
ATOM   7741  N  NH1 . ARG B 1 205 ? 185.927 213.302 273.233 1.00 102.06 ? 205 ARG B NH1 1 
ATOM   7742  N  NH2 . ARG B 1 205 ? 186.266 211.087 272.764 1.00 102.06 ? 205 ARG B NH2 1 
ATOM   7743  N  N   . LEU B 1 206 ? 189.765 211.722 279.470 1.00 95.65  ? 206 LEU B N   1 
ATOM   7744  C  CA  . LEU B 1 206 ? 190.898 211.006 280.045 1.00 95.65  ? 206 LEU B CA  1 
ATOM   7745  C  C   . LEU B 1 206 ? 190.455 210.090 281.181 1.00 95.65  ? 206 LEU B C   1 
ATOM   7746  O  O   . LEU B 1 206 ? 191.012 209.003 281.373 1.00 95.65  ? 206 LEU B O   1 
ATOM   7747  C  CB  . LEU B 1 206 ? 191.943 212.007 280.532 1.00 95.65  ? 206 LEU B CB  1 
ATOM   7748  C  CG  . LEU B 1 206 ? 193.126 211.428 281.299 1.00 95.65  ? 206 LEU B CG  1 
ATOM   7749  C  CD1 . LEU B 1 206 ? 193.896 210.463 280.423 1.00 95.65  ? 206 LEU B CD1 1 
ATOM   7750  C  CD2 . LEU B 1 206 ? 194.027 212.539 281.809 1.00 95.65  ? 206 LEU B CD2 1 
ATOM   7751  N  N   . GLN B 1 207 ? 189.446 210.514 281.945 1.00 100.06 ? 207 GLN B N   1 
ATOM   7752  C  CA  . GLN B 1 207 ? 189.079 209.806 283.169 1.00 100.06 ? 207 GLN B CA  1 
ATOM   7753  C  C   . GLN B 1 207 ? 187.949 208.799 282.983 1.00 100.06 ? 207 GLN B C   1 
ATOM   7754  O  O   . GLN B 1 207 ? 187.604 208.100 283.942 1.00 100.06 ? 207 GLN B O   1 
ATOM   7755  C  CB  . GLN B 1 207 ? 188.686 210.809 284.254 1.00 100.06 ? 207 GLN B CB  1 
ATOM   7756  C  CG  . GLN B 1 207 ? 189.859 211.467 284.947 1.00 100.06 ? 207 GLN B CG  1 
ATOM   7757  C  CD  . GLN B 1 207 ? 190.658 210.477 285.765 1.00 100.06 ? 207 GLN B CD  1 
ATOM   7758  O  OE1 . GLN B 1 207 ? 191.783 210.130 285.414 1.00 100.06 ? 207 GLN B OE1 1 
ATOM   7759  N  NE2 . GLN B 1 207 ? 190.083 210.023 286.870 1.00 100.06 ? 207 GLN B NE2 1 
ATOM   7760  N  N   . GLN B 1 208 ? 187.346 208.718 281.796 1.00 102.85 ? 208 GLN B N   1 
ATOM   7761  C  CA  . GLN B 1 208 ? 186.239 207.782 281.610 1.00 102.85 ? 208 GLN B CA  1 
ATOM   7762  C  C   . GLN B 1 208 ? 186.638 206.342 281.917 1.00 102.85 ? 208 GLN B C   1 
ATOM   7763  O  O   . GLN B 1 208 ? 186.191 205.771 282.916 1.00 102.85 ? 208 GLN B O   1 
ATOM   7764  C  CB  . GLN B 1 208 ? 185.696 207.868 280.180 1.00 102.85 ? 208 GLN B CB  1 
ATOM   7765  C  CG  . GLN B 1 208 ? 184.703 208.994 279.947 1.00 102.85 ? 208 GLN B CG  1 
ATOM   7766  C  CD  . GLN B 1 208 ? 184.260 209.088 278.500 1.00 102.85 ? 208 GLN B CD  1 
ATOM   7767  O  OE1 . GLN B 1 208 ? 184.733 208.340 277.644 1.00 102.85 ? 208 GLN B OE1 1 
ATOM   7768  N  NE2 . GLN B 1 208 ? 183.348 210.012 278.219 1.00 102.85 ? 208 GLN B NE2 1 
ATOM   7769  N  N   . LEU B 1 209 ? 187.475 205.747 281.068 1.00 100.17 ? 209 LEU B N   1 
ATOM   7770  C  CA  . LEU B 1 209 ? 188.005 204.414 281.333 1.00 100.17 ? 209 LEU B CA  1 
ATOM   7771  C  C   . LEU B 1 209 ? 189.452 204.313 280.871 1.00 100.17 ? 209 LEU B C   1 
ATOM   7772  O  O   . LEU B 1 209 ? 190.006 203.212 280.773 1.00 100.17 ? 209 LEU B O   1 
ATOM   7773  C  CB  . LEU B 1 209 ? 187.132 203.347 280.659 1.00 100.17 ? 209 LEU B CB  1 
ATOM   7774  C  CG  . LEU B 1 209 ? 186.902 203.387 279.143 1.00 100.17 ? 209 LEU B CG  1 
ATOM   7775  C  CD1 . LEU B 1 209 ? 187.974 202.621 278.375 1.00 100.17 ? 209 LEU B CD1 1 
ATOM   7776  C  CD2 . LEU B 1 209 ? 185.516 202.857 278.800 1.00 100.17 ? 209 LEU B CD2 1 
ATOM   7777  N  N   . LEU B 1 210 ? 190.077 205.457 280.599 1.00 94.52  ? 210 LEU B N   1 
ATOM   7778  C  CA  . LEU B 1 210 ? 191.331 205.495 279.855 1.00 94.52  ? 210 LEU B CA  1 
ATOM   7779  C  C   . LEU B 1 210 ? 192.538 205.759 280.744 1.00 94.52  ? 210 LEU B C   1 
ATOM   7780  O  O   . LEU B 1 210 ? 193.631 205.273 280.441 1.00 94.52  ? 210 LEU B O   1 
ATOM   7781  C  CB  . LEU B 1 210 ? 191.239 206.554 278.747 1.00 94.52  ? 210 LEU B CB  1 
ATOM   7782  C  CG  . LEU B 1 210 ? 190.518 206.194 277.443 1.00 94.52  ? 210 LEU B CG  1 
ATOM   7783  C  CD1 . LEU B 1 210 ? 189.017 206.079 277.645 1.00 94.52  ? 210 LEU B CD1 1 
ATOM   7784  C  CD2 . LEU B 1 210 ? 190.828 207.229 276.377 1.00 94.52  ? 210 LEU B CD2 1 
ATOM   7785  N  N   . TRP B 1 211 ? 192.373 206.505 281.834 1.00 90.54  ? 211 TRP B N   1 
ATOM   7786  C  CA  . TRP B 1 211 ? 193.502 206.996 282.612 1.00 90.54  ? 211 TRP B CA  1 
ATOM   7787  C  C   . TRP B 1 211 ? 194.394 205.875 283.129 1.00 90.54  ? 211 TRP B C   1 
ATOM   7788  O  O   . TRP B 1 211 ? 195.616 205.917 282.953 1.00 90.54  ? 211 TRP B O   1 
ATOM   7789  C  CB  . TRP B 1 211 ? 193.007 207.837 283.792 1.00 90.54  ? 211 TRP B CB  1 
ATOM   7790  C  CG  . TRP B 1 211 ? 194.033 208.018 284.889 1.00 90.54  ? 211 TRP B CG  1 
ATOM   7791  C  CD1 . TRP B 1 211 ? 194.260 207.183 285.946 1.00 90.54  ? 211 TRP B CD1 1 
ATOM   7792  C  CD2 . TRP B 1 211 ? 194.957 209.104 285.036 1.00 90.54  ? 211 TRP B CD2 1 
ATOM   7793  N  NE1 . TRP B 1 211 ? 195.272 207.676 286.731 1.00 90.54  ? 211 TRP B NE1 1 
ATOM   7794  C  CE2 . TRP B 1 211 ? 195.715 208.856 286.197 1.00 90.54  ? 211 TRP B CE2 1 
ATOM   7795  C  CE3 . TRP B 1 211 ? 195.218 210.261 284.299 1.00 90.54  ? 211 TRP B CE3 1 
ATOM   7796  C  CZ2 . TRP B 1 211 ? 196.711 209.720 286.636 1.00 90.54  ? 211 TRP B CZ2 1 
ATOM   7797  C  CZ3 . TRP B 1 211 ? 196.205 211.117 284.739 1.00 90.54  ? 211 TRP B CZ3 1 
ATOM   7798  C  CH2 . TRP B 1 211 ? 196.943 210.839 285.894 1.00 90.54  ? 211 TRP B CH2 1 
ATOM   7799  N  N   . LYS B 1 212 ? 193.797 204.870 283.768 1.00 89.27  ? 212 LYS B N   1 
ATOM   7800  C  CA  . LYS B 1 212 ? 194.592 203.923 284.540 1.00 89.27  ? 212 LYS B CA  1 
ATOM   7801  C  C   . LYS B 1 212 ? 195.356 202.944 283.657 1.00 89.27  ? 212 LYS B C   1 
ATOM   7802  O  O   . LYS B 1 212 ? 196.516 202.633 283.942 1.00 89.27  ? 212 LYS B O   1 
ATOM   7803  C  CB  . LYS B 1 212 ? 193.697 203.175 285.532 1.00 89.27  ? 212 LYS B CB  1 
ATOM   7804  C  CG  . LYS B 1 212 ? 192.611 202.314 284.904 1.00 89.27  ? 212 LYS B CG  1 
ATOM   7805  C  CD  . LYS B 1 212 ? 191.381 202.243 285.794 1.00 89.27  ? 212 LYS B CD  1 
ATOM   7806  C  CE  . LYS B 1 212 ? 190.219 201.573 285.079 1.00 89.27  ? 212 LYS B CE  1 
ATOM   7807  N  NZ  . LYS B 1 212 ? 190.023 202.114 283.705 1.00 89.27  ? 212 LYS B NZ  1 
ATOM   7808  N  N   . THR B 1 213 ? 194.737 202.443 282.589 1.00 91.86  ? 213 THR B N   1 
ATOM   7809  C  CA  . THR B 1 213 ? 195.314 201.337 281.834 1.00 91.86  ? 213 THR B CA  1 
ATOM   7810  C  C   . THR B 1 213 ? 195.305 201.516 280.325 1.00 91.86  ? 213 THR B C   1 
ATOM   7811  O  O   . THR B 1 213 ? 196.105 200.858 279.649 1.00 91.86  ? 213 THR B O   1 
ATOM   7812  C  CB  . THR B 1 213 ? 194.581 200.024 282.158 1.00 91.86  ? 213 THR B CB  1 
ATOM   7813  O  OG1 . THR B 1 213 ? 193.168 200.212 282.006 1.00 91.86  ? 213 THR B OG1 1 
ATOM   7814  C  CG2 . THR B 1 213 ? 194.875 199.572 283.581 1.00 91.86  ? 213 THR B CG2 1 
ATOM   7815  N  N   . ALA B 1 214 ? 194.447 202.364 279.770 1.00 87.57  ? 214 ALA B N   1 
ATOM   7816  C  CA  . ALA B 1 214 ? 194.225 202.391 278.331 1.00 87.57  ? 214 ALA B CA  1 
ATOM   7817  C  C   . ALA B 1 214 ? 195.241 203.303 277.654 1.00 87.57  ? 214 ALA B C   1 
ATOM   7818  O  O   . ALA B 1 214 ? 195.282 204.508 277.921 1.00 87.57  ? 214 ALA B O   1 
ATOM   7819  C  CB  . ALA B 1 214 ? 192.802 202.845 278.011 1.00 87.57  ? 214 ALA B CB  1 
ATOM   7820  N  N   . ARG B 1 215 ? 196.053 202.720 276.774 1.00 83.75  ? 215 ARG B N   1 
ATOM   7821  C  CA  . ARG B 1 215 ? 196.934 203.479 275.890 1.00 83.75  ? 215 ARG B CA  1 
ATOM   7822  C  C   . ARG B 1 215 ? 196.116 203.873 274.664 1.00 83.75  ? 215 ARG B C   1 
ATOM   7823  O  O   . ARG B 1 215 ? 196.237 203.303 273.577 1.00 83.75  ? 215 ARG B O   1 
ATOM   7824  C  CB  . ARG B 1 215 ? 198.159 202.654 275.518 1.00 83.75  ? 215 ARG B CB  1 
ATOM   7825  C  CG  . ARG B 1 215 ? 199.165 203.387 274.646 1.00 83.75  ? 215 ARG B CG  1 
ATOM   7826  C  CD  . ARG B 1 215 ? 200.282 202.463 274.189 1.00 83.75  ? 215 ARG B CD  1 
ATOM   7827  N  NE  . ARG B 1 215 ? 201.149 203.104 273.208 1.00 83.75  ? 215 ARG B NE  1 
ATOM   7828  C  CZ  . ARG B 1 215 ? 202.210 202.530 272.657 1.00 83.75  ? 215 ARG B CZ  1 
ATOM   7829  N  NH1 . ARG B 1 215 ? 202.567 201.295 272.967 1.00 83.75  ? 215 ARG B NH1 1 
ATOM   7830  N  NH2 . ARG B 1 215 ? 202.930 203.213 271.771 1.00 83.75  ? 215 ARG B NH2 1 
ATOM   7831  N  N   . ASP B 1 216 ? 195.251 204.868 274.853 1.00 87.51  ? 216 ASP B N   1 
ATOM   7832  C  CA  . ASP B 1 216 ? 194.296 205.269 273.830 1.00 87.51  ? 216 ASP B CA  1 
ATOM   7833  C  C   . ASP B 1 216 ? 194.542 206.713 273.421 1.00 87.51  ? 216 ASP B C   1 
ATOM   7834  O  O   . ASP B 1 216 ? 195.074 207.518 274.187 1.00 87.51  ? 216 ASP B O   1 
ATOM   7835  C  CB  . ASP B 1 216 ? 192.850 205.099 274.312 1.00 87.51  ? 216 ASP B CB  1 
ATOM   7836  C  CG  . ASP B 1 216 ? 191.879 204.867 273.171 1.00 87.51  ? 216 ASP B CG  1 
ATOM   7837  O  OD1 . ASP B 1 216 ? 192.324 204.855 272.004 1.00 87.51  ? 216 ASP B OD1 1 
ATOM   7838  O  OD2 . ASP B 1 216 ? 190.672 204.695 273.441 1.00 87.51  ? 216 ASP B OD2 1 
ATOM   7839  N  N   . GLN B 1 217 ? 194.139 207.034 272.200 1.00 85.68  ? 217 GLN B N   1 
ATOM   7840  C  CA  . GLN B 1 217 ? 194.392 208.334 271.604 1.00 85.68  ? 217 GLN B CA  1 
ATOM   7841  C  C   . GLN B 1 217 ? 193.075 208.979 271.199 1.00 85.68  ? 217 GLN B C   1 
ATOM   7842  O  O   . GLN B 1 217 ? 192.095 208.301 270.882 1.00 85.68  ? 217 GLN B O   1 
ATOM   7843  C  CB  . GLN B 1 217 ? 195.310 208.209 270.382 1.00 85.68  ? 217 GLN B CB  1 
ATOM   7844  C  CG  . GLN B 1 217 ? 196.673 207.614 270.680 1.00 85.68  ? 217 GLN B CG  1 
ATOM   7845  C  CD  . GLN B 1 217 ? 196.634 206.105 270.807 1.00 85.68  ? 217 GLN B CD  1 
ATOM   7846  O  OE1 . GLN B 1 217 ? 196.974 205.549 271.851 1.00 85.68  ? 217 GLN B OE1 1 
ATOM   7847  N  NE2 . GLN B 1 217 ? 196.217 205.433 269.741 1.00 85.68  ? 217 GLN B NE2 1 
ATOM   7848  N  N   . ASP B 1 218 ? 193.059 210.308 271.207 1.00 86.75  ? 218 ASP B N   1 
ATOM   7849  C  CA  . ASP B 1 218 ? 191.896 211.038 270.721 1.00 86.75  ? 218 ASP B CA  1 
ATOM   7850  C  C   . ASP B 1 218 ? 192.320 212.446 270.337 1.00 86.75  ? 218 ASP B C   1 
ATOM   7851  O  O   . ASP B 1 218 ? 193.344 212.949 270.808 1.00 86.75  ? 218 ASP B O   1 
ATOM   7852  C  CB  . ASP B 1 218 ? 190.779 211.083 271.770 1.00 86.75  ? 218 ASP B CB  1 
ATOM   7853  C  CG  . ASP B 1 218 ? 189.415 211.326 271.156 1.00 86.75  ? 218 ASP B CG  1 
ATOM   7854  O  OD1 . ASP B 1 218 ? 189.348 211.591 269.937 1.00 86.75  ? 218 ASP B OD1 1 
ATOM   7855  O  OD2 . ASP B 1 218 ? 188.410 211.251 271.891 1.00 86.75  ? 218 ASP B OD2 1 
ATOM   7856  N  N   . GLU B 1 219 ? 191.521 213.070 269.478 1.00 81.23  ? 219 GLU B N   1 
ATOM   7857  C  CA  . GLU B 1 219 ? 191.800 214.424 269.026 1.00 81.23  ? 219 GLU B CA  1 
ATOM   7858  C  C   . GLU B 1 219 ? 191.178 215.434 269.977 1.00 81.23  ? 219 GLU B C   1 
ATOM   7859  O  O   . GLU B 1 219 ? 190.016 215.304 270.370 1.00 81.23  ? 219 GLU B O   1 
ATOM   7860  C  CB  . GLU B 1 219 ? 191.259 214.642 267.613 1.00 81.23  ? 219 GLU B CB  1 
ATOM   7861  C  CG  . GLU B 1 219 ? 191.918 213.784 266.545 1.00 81.23  ? 219 GLU B CG  1 
ATOM   7862  C  CD  . GLU B 1 219 ? 191.252 212.431 266.388 1.00 81.23  ? 219 GLU B CD  1 
ATOM   7863  O  OE1 . GLU B 1 219 ? 190.229 212.188 267.061 1.00 81.23  ? 219 GLU B OE1 1 
ATOM   7864  O  OE2 . GLU B 1 219 ? 191.753 211.610 265.591 1.00 81.23  ? 219 GLU B OE2 1 
ATOM   7865  N  N   . PHE B 1 220 ? 191.956 216.446 270.347 1.00 82.08  ? 220 PHE B N   1 
ATOM   7866  C  CA  . PHE B 1 220 ? 191.473 217.505 271.215 1.00 82.08  ? 220 PHE B CA  1 
ATOM   7867  C  C   . PHE B 1 220 ? 191.914 218.841 270.638 1.00 82.08  ? 220 PHE B C   1 
ATOM   7868  O  O   . PHE B 1 220 ? 192.677 218.900 269.670 1.00 82.08  ? 220 PHE B O   1 
ATOM   7869  C  CB  . PHE B 1 220 ? 191.987 217.326 272.646 1.00 82.08  ? 220 PHE B CB  1 
ATOM   7870  C  CG  . PHE B 1 220 ? 191.764 215.952 273.204 1.00 82.08  ? 220 PHE B CG  1 
ATOM   7871  C  CD1 . PHE B 1 220 ? 190.517 215.572 273.661 1.00 82.08  ? 220 PHE B CD1 1 
ATOM   7872  C  CD2 . PHE B 1 220 ? 192.804 215.047 273.282 1.00 82.08  ? 220 PHE B CD2 1 
ATOM   7873  C  CE1 . PHE B 1 220 ? 190.309 214.311 274.182 1.00 82.08  ? 220 PHE B CE1 1 
ATOM   7874  C  CE2 . PHE B 1 220 ? 192.604 213.787 273.801 1.00 82.08  ? 220 PHE B CE2 1 
ATOM   7875  C  CZ  . PHE B 1 220 ? 191.356 213.419 274.253 1.00 82.08  ? 220 PHE B CZ  1 
ATOM   7876  N  N   . LEU B 1 221 ? 191.433 219.923 271.237 1.00 82.84  ? 221 LEU B N   1 
ATOM   7877  C  CA  . LEU B 1 221 ? 191.846 221.261 270.853 1.00 82.84  ? 221 LEU B CA  1 
ATOM   7878  C  C   . LEU B 1 221 ? 192.421 221.970 272.068 1.00 82.84  ? 221 LEU B C   1 
ATOM   7879  O  O   . LEU B 1 221 ? 191.929 221.812 273.187 1.00 82.84  ? 221 LEU B O   1 
ATOM   7880  C  CB  . LEU B 1 221 ? 190.690 222.073 270.267 1.00 82.84  ? 221 LEU B CB  1 
ATOM   7881  C  CG  . LEU B 1 221 ? 190.355 221.789 268.801 1.00 82.84  ? 221 LEU B CG  1 
ATOM   7882  C  CD1 . LEU B 1 221 ? 189.471 220.557 268.684 1.00 82.84  ? 221 LEU B CD1 1 
ATOM   7883  C  CD2 . LEU B 1 221 ? 189.704 222.998 268.144 1.00 82.84  ? 221 LEU B CD2 1 
ATOM   7884  N  N   . LEU B 1 222 ? 193.484 222.736 271.844 1.00 84.96  ? 222 LEU B N   1 
ATOM   7885  C  CA  . LEU B 1 222 ? 194.178 223.405 272.935 1.00 84.96  ? 222 LEU B CA  1 
ATOM   7886  C  C   . LEU B 1 222 ? 194.437 224.858 272.564 1.00 84.96  ? 222 LEU B C   1 
ATOM   7887  O  O   . LEU B 1 222 ? 194.453 225.232 271.389 1.00 84.96  ? 222 LEU B O   1 
ATOM   7888  C  CB  . LEU B 1 222 ? 195.493 222.699 273.297 1.00 84.96  ? 222 LEU B CB  1 
ATOM   7889  C  CG  . LEU B 1 222 ? 195.477 221.540 274.307 1.00 84.96  ? 222 LEU B CG  1 
ATOM   7890  C  CD1 . LEU B 1 222 ? 194.981 222.019 275.662 1.00 84.96  ? 222 LEU B CD1 1 
ATOM   7891  C  CD2 . LEU B 1 222 ? 194.681 220.334 273.837 1.00 84.96  ? 222 LEU B CD2 1 
ATOM   7892  N  N   . LEU B 1 223 ? 194.636 225.679 273.594 1.00 87.02  ? 223 LEU B N   1 
ATOM   7893  C  CA  . LEU B 1 223 ? 194.845 227.112 273.451 1.00 87.02  ? 223 LEU B CA  1 
ATOM   7894  C  C   . LEU B 1 223 ? 196.273 227.467 273.838 1.00 87.02  ? 223 LEU B C   1 
ATOM   7895  O  O   . LEU B 1 223 ? 196.783 226.997 274.858 1.00 87.02  ? 223 LEU B O   1 
ATOM   7896  C  CB  . LEU B 1 223 ? 193.854 227.901 274.316 1.00 87.02  ? 223 LEU B CB  1 
ATOM   7897  C  CG  . LEU B 1 223 ? 194.091 229.407 274.442 1.00 87.02  ? 223 LEU B CG  1 
ATOM   7898  C  CD1 . LEU B 1 223 ? 194.037 230.077 273.079 1.00 87.02  ? 223 LEU B CD1 1 
ATOM   7899  C  CD2 . LEU B 1 223 ? 193.077 230.034 275.387 1.00 87.02  ? 223 LEU B CD2 1 
ATOM   7900  N  N   . THR B 1 224 ? 196.907 228.303 273.024 1.00 84.10  ? 224 THR B N   1 
ATOM   7901  C  CA  . THR B 1 224 ? 198.302 228.670 273.194 1.00 84.10  ? 224 THR B CA  1 
ATOM   7902  C  C   . THR B 1 224 ? 198.425 230.082 273.760 1.00 84.10  ? 224 THR B C   1 
ATOM   7903  O  O   . THR B 1 224 ? 197.442 230.727 274.131 1.00 84.10  ? 224 THR B O   1 
ATOM   7904  C  CB  . THR B 1 224 ? 199.046 228.552 271.864 1.00 84.10  ? 224 THR B CB  1 
ATOM   7905  O  OG1 . THR B 1 224 ? 198.443 229.422 270.899 1.00 84.10  ? 224 THR B OG1 1 
ATOM   7906  C  CG2 . THR B 1 224 ? 198.993 227.122 271.350 1.00 84.10  ? 224 THR B CG2 1 
ATOM   7907  N  N   . ARG B 1 225 ? 199.668 230.562 273.836 1.00 81.35  ? 225 ARG B N   1 
ATOM   7908  C  CA  . ARG B 1 225 ? 199.943 231.913 274.307 1.00 81.35  ? 225 ARG B CA  1 
ATOM   7909  C  C   . ARG B 1 225 ? 199.626 232.978 273.267 1.00 81.35  ? 225 ARG B C   1 
ATOM   7910  O  O   . ARG B 1 225 ? 199.175 234.068 273.634 1.00 81.35  ? 225 ARG B O   1 
ATOM   7911  C  CB  . ARG B 1 225 ? 201.409 232.032 274.721 1.00 81.35  ? 225 ARG B CB  1 
ATOM   7912  C  CG  . ARG B 1 225 ? 201.714 231.504 276.107 1.00 81.35  ? 225 ARG B CG  1 
ATOM   7913  C  CD  . ARG B 1 225 ? 200.854 232.165 277.158 1.00 81.35  ? 225 ARG B CD  1 
ATOM   7914  N  NE  . ARG B 1 225 ? 199.616 231.434 277.394 1.00 81.35  ? 225 ARG B NE  1 
ATOM   7915  C  CZ  . ARG B 1 225 ? 199.537 230.287 278.052 1.00 81.35  ? 225 ARG B CZ  1 
ATOM   7916  N  NH1 . ARG B 1 225 ? 200.610 229.706 278.560 1.00 81.35  ? 225 ARG B NH1 1 
ATOM   7917  N  NH2 . ARG B 1 225 ? 198.348 229.712 278.208 1.00 81.35  ? 225 ARG B NH2 1 
ATOM   7918  N  N   . THR B 1 226 ? 199.860 232.691 271.985 1.00 88.63  ? 226 THR B N   1 
ATOM   7919  C  CA  . THR B 1 226 ? 199.587 233.675 270.942 1.00 88.63  ? 226 THR B CA  1 
ATOM   7920  C  C   . THR B 1 226 ? 198.099 233.988 270.852 1.00 88.63  ? 226 THR B C   1 
ATOM   7921  O  O   . THR B 1 226 ? 197.714 235.147 270.659 1.00 88.63  ? 226 THR B O   1 
ATOM   7922  C  CB  . THR B 1 226 ? 200.113 233.175 269.597 1.00 88.63  ? 226 THR B CB  1 
ATOM   7923  O  OG1 . THR B 1 226 ? 201.431 232.639 269.767 1.00 88.63  ? 226 THR B OG1 1 
ATOM   7924  C  CG2 . THR B 1 226 ? 200.160 234.311 268.587 1.00 88.63  ? 226 THR B CG2 1 
ATOM   7925  N  N   . GLY B 1 227 ? 197.249 232.973 270.989 1.00 92.94  ? 227 GLY B N   1 
ATOM   7926  C  CA  . GLY B 1 227 ? 195.815 233.185 270.967 1.00 92.94  ? 227 GLY B CA  1 
ATOM   7927  C  C   . GLY B 1 227 ? 195.043 232.148 270.178 1.00 92.94  ? 227 GLY B C   1 
ATOM   7928  O  O   . GLY B 1 227 ? 193.864 231.907 270.449 1.00 92.94  ? 227 GLY B O   1 
ATOM   7929  N  N   . GLU B 1 228 ? 195.692 231.529 269.197 1.00 90.72  ? 228 GLU B N   1 
ATOM   7930  C  CA  . GLU B 1 228 ? 195.023 230.546 268.363 1.00 90.72  ? 228 GLU B CA  1 
ATOM   7931  C  C   . GLU B 1 228 ? 194.883 229.218 269.100 1.00 90.72  ? 228 GLU B C   1 
ATOM   7932  O  O   . GLU B 1 228 ? 195.585 228.937 270.074 1.00 90.72  ? 228 GLU B O   1 
ATOM   7933  C  CB  . GLU B 1 228 ? 195.786 230.338 267.057 1.00 90.72  ? 228 GLU B CB  1 
ATOM   7934  C  CG  . GLU B 1 228 ? 196.009 231.608 266.254 1.00 90.72  ? 228 GLU B CG  1 
ATOM   7935  C  CD  . GLU B 1 228 ? 197.209 232.396 266.737 1.00 90.72  ? 228 GLU B CD  1 
ATOM   7936  O  OE1 . GLU B 1 228 ? 197.950 231.876 267.598 1.00 90.72  ? 228 GLU B OE1 1 
ATOM   7937  O  OE2 . GLU B 1 228 ? 197.411 233.531 266.258 1.00 90.72  ? 228 GLU B OE2 1 
ATOM   7938  N  N   . LYS B 1 229 ? 193.958 228.397 268.619 1.00 89.91  ? 229 LYS B N   1 
ATOM   7939  C  CA  . LYS B 1 229 ? 193.732 227.064 269.155 1.00 89.91  ? 229 LYS B CA  1 
ATOM   7940  C  C   . LYS B 1 229 ? 194.072 226.027 268.094 1.00 89.91  ? 229 LYS B C   1 
ATOM   7941  O  O   . LYS B 1 229 ? 193.715 226.184 266.922 1.00 89.91  ? 229 LYS B O   1 
ATOM   7942  C  CB  . LYS B 1 229 ? 192.284 226.898 269.624 1.00 89.91  ? 229 LYS B CB  1 
ATOM   7943  C  CG  . LYS B 1 229 ? 191.927 227.779 270.814 1.00 89.91  ? 229 LYS B CG  1 
ATOM   7944  C  CD  . LYS B 1 229 ? 190.741 227.228 271.590 1.00 89.91  ? 229 LYS B CD  1 
ATOM   7945  C  CE  . LYS B 1 229 ? 190.466 228.056 272.839 1.00 89.91  ? 229 LYS B CE  1 
ATOM   7946  N  NZ  . LYS B 1 229 ? 189.603 229.234 272.559 1.00 89.91  ? 229 LYS B NZ  1 
ATOM   7947  N  N   . ILE B 1 230 ? 194.763 224.967 268.508 1.00 82.21  ? 230 ILE B N   1 
ATOM   7948  C  CA  . ILE B 1 230 ? 195.323 223.985 267.588 1.00 82.21  ? 230 ILE B CA  1 
ATOM   7949  C  C   . ILE B 1 230 ? 194.780 222.605 267.925 1.00 82.21  ? 230 ILE B C   1 
ATOM   7950  O  O   . ILE B 1 230 ? 194.444 222.320 269.082 1.00 82.21  ? 230 ILE B O   1 
ATOM   7951  C  CB  . ILE B 1 230 ? 196.862 223.980 267.637 1.00 82.21  ? 230 ILE B CB  1 
ATOM   7952  C  CG1 . ILE B 1 230 ? 197.345 223.707 269.059 1.00 82.21  ? 230 ILE B CG1 1 
ATOM   7953  C  CG2 . ILE B 1 230 ? 197.410 225.303 267.139 1.00 82.21  ? 230 ILE B CG2 1 
ATOM   7954  C  CD1 . ILE B 1 230 ? 198.843 223.707 269.199 1.00 82.21  ? 230 ILE B CD1 1 
ATOM   7955  N  N   . TRP B 1 231 ? 194.690 221.752 266.905 1.00 80.17  ? 231 TRP B N   1 
ATOM   7956  C  CA  . TRP B 1 231 ? 194.324 220.359 267.113 1.00 80.17  ? 231 TRP B CA  1 
ATOM   7957  C  C   . TRP B 1 231 ? 195.539 219.562 267.561 1.00 80.17  ? 231 TRP B C   1 
ATOM   7958  O  O   . TRP B 1 231 ? 196.641 219.732 267.037 1.00 80.17  ? 231 TRP B O   1 
ATOM   7959  C  CB  . TRP B 1 231 ? 193.745 219.760 265.835 1.00 80.17  ? 231 TRP B CB  1 
ATOM   7960  C  CG  . TRP B 1 231 ? 192.380 220.263 265.517 1.00 80.17  ? 231 TRP B CG  1 
ATOM   7961  C  CD1 . TRP B 1 231 ? 191.197 219.699 265.880 1.00 80.17  ? 231 TRP B CD1 1 
ATOM   7962  C  CD2 . TRP B 1 231 ? 192.052 221.445 264.779 1.00 80.17  ? 231 TRP B CD2 1 
ATOM   7963  N  NE1 . TRP B 1 231 ? 190.149 220.452 265.413 1.00 80.17  ? 231 TRP B NE1 1 
ATOM   7964  C  CE2 . TRP B 1 231 ? 190.647 221.531 264.732 1.00 80.17  ? 231 TRP B CE2 1 
ATOM   7965  C  CE3 . TRP B 1 231 ? 192.810 222.438 264.151 1.00 80.17  ? 231 TRP B CE3 1 
ATOM   7966  C  CZ2 . TRP B 1 231 ? 189.984 222.569 264.081 1.00 80.17  ? 231 TRP B CZ2 1 
ATOM   7967  C  CZ3 . TRP B 1 231 ? 192.149 223.469 263.505 1.00 80.17  ? 231 TRP B CZ3 1 
ATOM   7968  C  CH2 . TRP B 1 231 ? 190.750 223.526 263.476 1.00 80.17  ? 231 TRP B CH2 1 
ATOM   7969  N  N   . ILE B 1 232 ? 195.331 218.687 268.538 1.00 73.83  ? 232 ILE B N   1 
ATOM   7970  C  CA  . ILE B 1 232 ? 196.410 217.932 269.156 1.00 73.83  ? 232 ILE B CA  1 
ATOM   7971  C  C   . ILE B 1 232 ? 195.963 216.492 269.358 1.00 73.83  ? 232 ILE B C   1 
ATOM   7972  O  O   . ILE B 1 232 ? 194.842 216.235 269.814 1.00 73.83  ? 232 ILE B O   1 
ATOM   7973  C  CB  . ILE B 1 232 ? 196.832 218.563 270.497 1.00 73.83  ? 232 ILE B CB  1 
ATOM   7974  C  CG1 . ILE B 1 232 ? 197.507 219.912 270.262 1.00 73.83  ? 232 ILE B CG1 1 
ATOM   7975  C  CG2 . ILE B 1 232 ? 197.741 217.636 271.268 1.00 73.83  ? 232 ILE B CG2 1 
ATOM   7976  C  CD1 . ILE B 1 232 ? 198.809 219.817 269.500 1.00 73.83  ? 232 ILE B CD1 1 
ATOM   7977  N  N   . LYS B 1 233 ? 196.838 215.554 269.010 1.00 71.16  ? 233 LYS B N   1 
ATOM   7978  C  CA  . LYS B 1 233 ? 196.697 214.182 269.465 1.00 71.16  ? 233 LYS B CA  1 
ATOM   7979  C  C   . LYS B 1 233 ? 197.421 214.034 270.793 1.00 71.16  ? 233 LYS B C   1 
ATOM   7980  O  O   . LYS B 1 233 ? 198.533 214.535 270.971 1.00 71.16  ? 233 LYS B O   1 
ATOM   7981  C  CB  . LYS B 1 233 ? 197.261 213.195 268.447 1.00 71.16  ? 233 LYS B CB  1 
ATOM   7982  C  CG  . LYS B 1 233 ? 196.677 213.327 267.060 1.00 71.16  ? 233 LYS B CG  1 
ATOM   7983  C  CD  . LYS B 1 233 ? 195.324 212.649 266.974 1.00 71.16  ? 233 LYS B CD  1 
ATOM   7984  C  CE  . LYS B 1 233 ? 195.465 211.137 266.993 1.00 71.16  ? 233 LYS B CE  1 
ATOM   7985  N  NZ  . LYS B 1 233 ? 194.343 210.466 266.280 1.00 71.16  ? 233 LYS B NZ  1 
ATOM   7986  N  N   . ALA B 1 234 ? 196.789 213.326 271.722 1.00 67.32  ? 234 ALA B N   1 
ATOM   7987  C  CA  . ALA B 1 234 ? 197.203 213.300 273.119 1.00 67.32  ? 234 ALA B CA  1 
ATOM   7988  C  C   . ALA B 1 234 ? 197.430 211.872 273.587 1.00 67.32  ? 234 ALA B C   1 
ATOM   7989  O  O   . ALA B 1 234 ? 196.870 211.424 274.588 1.00 67.32  ? 234 ALA B O   1 
ATOM   7990  C  CB  . ALA B 1 234 ? 196.179 214.004 274.002 1.00 67.32  ? 234 ALA B CB  1 
ATOM   7991  N  N   . SER B 1 235 ? 198.240 211.130 272.836 1.00 71.57  ? 235 SER B N   1 
ATOM   7992  C  CA  . SER B 1 235 ? 198.545 209.747 273.177 1.00 71.57  ? 235 SER B CA  1 
ATOM   7993  C  C   . SER B 1 235 ? 199.009 209.633 274.623 1.00 71.57  ? 235 SER B C   1 
ATOM   7994  O  O   . SER B 1 235 ? 199.902 210.364 275.066 1.00 71.57  ? 235 SER B O   1 
ATOM   7995  C  CB  . SER B 1 235 ? 199.620 209.202 272.236 1.00 71.57  ? 235 SER B CB  1 
ATOM   7996  O  OG  . SER B 1 235 ? 199.267 209.404 270.879 1.00 71.57  ? 235 SER B OG  1 
ATOM   7997  N  N   . ILE B 1 236 ? 198.400 208.698 275.348 1.00 74.03  ? 236 ILE B N   1 
ATOM   7998  C  CA  . ILE B 1 236 ? 198.546 208.566 276.790 1.00 74.03  ? 236 ILE B CA  1 
ATOM   7999  C  C   . ILE B 1 236 ? 199.041 207.163 277.114 1.00 74.03  ? 236 ILE B C   1 
ATOM   8000  O  O   . ILE B 1 236 ? 198.694 206.186 276.449 1.00 74.03  ? 236 ILE B O   1 
ATOM   8001  C  CB  . ILE B 1 236 ? 197.219 208.860 277.522 1.00 74.03  ? 236 ILE B CB  1 
ATOM   8002  C  CG1 . ILE B 1 236 ? 197.407 208.791 279.029 1.00 74.03  ? 236 ILE B CG1 1 
ATOM   8003  C  CG2 . ILE B 1 236 ? 196.133 207.889 277.096 1.00 74.03  ? 236 ILE B CG2 1 
ATOM   8004  C  CD1 . ILE B 1 236 ? 198.390 209.766 279.519 1.00 74.03  ? 236 ILE B CD1 1 
ATOM   8005  N  N   . SER B 1 237 ? 199.879 207.072 278.143 1.00 71.21  ? 237 SER B N   1 
ATOM   8006  C  CA  . SER B 1 237 ? 200.277 205.743 278.590 1.00 71.21  ? 237 SER B CA  1 
ATOM   8007  C  C   . SER B 1 237 ? 200.705 205.743 280.051 1.00 71.21  ? 237 SER B C   1 
ATOM   8008  O  O   . SER B 1 237 ? 201.459 206.624 280.483 1.00 71.21  ? 237 SER B O   1 
ATOM   8009  C  CB  . SER B 1 237 ? 201.410 205.196 277.723 1.00 71.21  ? 237 SER B CB  1 
ATOM   8010  O  OG  . SER B 1 237 ? 201.770 203.890 278.136 1.00 71.21  ? 237 SER B OG  1 
ATOM   8011  N  N   . PRO B 1 238 ? 200.257 204.770 280.835 1.00 77.42  ? 238 PRO B N   1 
ATOM   8012  C  CA  . PRO B 1 238 ? 200.690 204.665 282.228 1.00 77.42  ? 238 PRO B CA  1 
ATOM   8013  C  C   . PRO B 1 238 ? 201.917 203.777 282.382 1.00 77.42  ? 238 PRO B C   1 
ATOM   8014  O  O   . PRO B 1 238 ? 202.229 202.940 281.533 1.00 77.42  ? 238 PRO B O   1 
ATOM   8015  C  CB  . PRO B 1 238 ? 199.473 204.030 282.916 1.00 77.42  ? 238 PRO B CB  1 
ATOM   8016  C  CG  . PRO B 1 238 ? 198.708 203.331 281.806 1.00 77.42  ? 238 PRO B CG  1 
ATOM   8017  C  CD  . PRO B 1 238 ? 199.301 203.713 280.479 1.00 77.42  ? 238 PRO B CD  1 
ATOM   8018  N  N   . VAL B 1 239 ? 202.614 203.976 283.500 1.00 81.23  ? 239 VAL B N   1 
ATOM   8019  C  CA  . VAL B 1 239 ? 203.810 203.216 283.839 1.00 81.23  ? 239 VAL B CA  1 
ATOM   8020  C  C   . VAL B 1 239 ? 203.693 202.804 285.301 1.00 81.23  ? 239 VAL B C   1 
ATOM   8021  O  O   . VAL B 1 239 ? 203.648 203.666 286.188 1.00 81.23  ? 239 VAL B O   1 
ATOM   8022  C  CB  . VAL B 1 239 ? 205.098 204.017 283.611 1.00 81.23  ? 239 VAL B CB  1 
ATOM   8023  C  CG1 . VAL B 1 239 ? 206.294 203.254 284.144 1.00 81.23  ? 239 VAL B CG1 1 
ATOM   8024  C  CG2 . VAL B 1 239 ? 205.278 204.325 282.135 1.00 81.23  ? 239 VAL B CG2 1 
ATOM   8025  N  N   . TYR B 1 240 ? 203.652 201.496 285.554 1.00 87.54  ? 240 TYR B N   1 
ATOM   8026  C  CA  . TYR B 1 240 ? 203.602 200.946 286.903 1.00 87.54  ? 240 TYR B CA  1 
ATOM   8027  C  C   . TYR B 1 240 ? 204.971 200.412 287.288 1.00 87.54  ? 240 TYR B C   1 
ATOM   8028  O  O   . TYR B 1 240 ? 205.700 199.887 286.441 1.00 87.54  ? 240 TYR B O   1 
ATOM   8029  C  CB  . TYR B 1 240 ? 202.574 199.819 287.013 1.00 87.54  ? 240 TYR B CB  1 
ATOM   8030  C  CG  . TYR B 1 240 ? 201.281 200.074 286.283 1.00 87.54  ? 240 TYR B CG  1 
ATOM   8031  C  CD1 . TYR B 1 240 ? 200.354 200.978 286.774 1.00 87.54  ? 240 TYR B CD1 1 
ATOM   8032  C  CD2 . TYR B 1 240 ? 200.986 199.405 285.105 1.00 87.54  ? 240 TYR B CD2 1 
ATOM   8033  C  CE1 . TYR B 1 240 ? 199.175 201.216 286.111 1.00 87.54  ? 240 TYR B CE1 1 
ATOM   8034  C  CE2 . TYR B 1 240 ? 199.807 199.634 284.435 1.00 87.54  ? 240 TYR B CE2 1 
ATOM   8035  C  CZ  . TYR B 1 240 ? 198.905 200.541 284.941 1.00 87.54  ? 240 TYR B CZ  1 
ATOM   8036  O  OH  . TYR B 1 240 ? 197.727 200.774 284.275 1.00 87.54  ? 240 TYR B OH  1 
ATOM   8037  N  N   . ASP B 1 241 ? 205.306 200.528 288.568 1.00 95.79  ? 241 ASP B N   1 
ATOM   8038  C  CA  . ASP B 1 241 ? 206.527 199.927 289.087 1.00 95.79  ? 241 ASP B CA  1 
ATOM   8039  C  C   . ASP B 1 241 ? 206.310 198.436 289.314 1.00 95.79  ? 241 ASP B C   1 
ATOM   8040  O  O   . ASP B 1 241 ? 205.324 197.870 288.831 1.00 95.79  ? 241 ASP B O   1 
ATOM   8041  C  CB  . ASP B 1 241 ? 206.960 200.622 290.379 1.00 95.79  ? 241 ASP B CB  1 
ATOM   8042  C  CG  . ASP B 1 241 ? 207.667 201.936 290.119 1.00 95.79  ? 241 ASP B CG  1 
ATOM   8043  O  OD1 . ASP B 1 241 ? 207.820 202.300 288.934 1.00 95.79  ? 241 ASP B OD1 1 
ATOM   8044  O  OD2 . ASP B 1 241 ? 208.061 202.609 291.094 1.00 95.79  ? 241 ASP B OD2 1 
ATOM   8045  N  N   . VAL B 1 242 ? 207.230 197.790 290.033 1.00 97.58  ? 242 VAL B N   1 
ATOM   8046  C  CA  . VAL B 1 242 ? 207.113 196.352 290.272 1.00 97.58  ? 242 VAL B CA  1 
ATOM   8047  C  C   . VAL B 1 242 ? 205.824 196.036 291.021 1.00 97.58  ? 242 VAL B C   1 
ATOM   8048  O  O   . VAL B 1 242 ? 205.139 195.049 290.724 1.00 97.58  ? 242 VAL B O   1 
ATOM   8049  C  CB  . VAL B 1 242 ? 208.350 195.837 291.032 1.00 97.58  ? 242 VAL B CB  1 
ATOM   8050  C  CG1 . VAL B 1 242 ? 208.247 194.337 291.265 1.00 97.58  ? 242 VAL B CG1 1 
ATOM   8051  C  CG2 . VAL B 1 242 ? 209.622 196.179 290.270 1.00 97.58  ? 242 VAL B CG2 1 
ATOM   8052  N  N   . LEU B 1 243 ? 205.464 196.876 291.987 1.00 92.80  ? 243 LEU B N   1 
ATOM   8053  C  CA  . LEU B 1 243 ? 204.296 196.649 292.830 1.00 92.80  ? 243 LEU B CA  1 
ATOM   8054  C  C   . LEU B 1 243 ? 202.976 196.868 292.103 1.00 92.80  ? 243 LEU B C   1 
ATOM   8055  O  O   . LEU B 1 243 ? 201.925 196.836 292.751 1.00 92.80  ? 243 LEU B O   1 
ATOM   8056  C  CB  . LEU B 1 243 ? 204.358 197.552 294.064 1.00 92.80  ? 243 LEU B CB  1 
ATOM   8057  C  CG  . LEU B 1 243 ? 205.627 197.457 294.912 1.00 92.80  ? 243 LEU B CG  1 
ATOM   8058  C  CD1 . LEU B 1 243 ? 205.532 198.368 296.126 1.00 92.80  ? 243 LEU B CD1 1 
ATOM   8059  C  CD2 . LEU B 1 243 ? 205.885 196.019 295.335 1.00 92.80  ? 243 LEU B CD2 1 
ATOM   8060  N  N   . ALA B 1 244 ? 203.005 197.111 290.793 1.00 90.92  ? 244 ALA B N   1 
ATOM   8061  C  CA  . ALA B 1 244 ? 201.844 197.329 289.933 1.00 90.92  ? 244 ALA B CA  1 
ATOM   8062  C  C   . ALA B 1 244 ? 201.088 198.607 290.271 1.00 90.92  ? 244 ALA B C   1 
ATOM   8063  O  O   . ALA B 1 244 ? 200.099 198.921 289.596 1.00 90.92  ? 244 ALA B O   1 
ATOM   8064  C  CB  . ALA B 1 244 ? 200.863 196.146 289.956 1.00 90.92  ? 244 ALA B CB  1 
ATOM   8065  N  N   . HIS B 1 245 ? 201.512 199.355 291.285 1.00 92.91  ? 245 HIS B N   1 
ATOM   8066  C  CA  . HIS B 1 245 ? 200.906 200.646 291.564 1.00 92.91  ? 245 HIS B CA  1 
ATOM   8067  C  C   . HIS B 1 245 ? 201.233 201.623 290.443 1.00 92.91  ? 245 HIS B C   1 
ATOM   8068  O  O   . HIS B 1 245 ? 202.301 201.551 289.829 1.00 92.91  ? 245 HIS B O   1 
ATOM   8069  C  CB  . HIS B 1 245 ? 201.404 201.196 292.900 1.00 92.91  ? 245 HIS B CB  1 
ATOM   8070  C  CG  . HIS B 1 245 ? 201.092 200.320 294.073 1.00 92.91  ? 245 HIS B CG  1 
ATOM   8071  N  ND1 . HIS B 1 245 ? 201.532 200.602 295.348 1.00 92.91  ? 245 HIS B ND1 1 
ATOM   8072  C  CD2 . HIS B 1 245 ? 200.380 199.172 294.166 1.00 92.91  ? 245 HIS B CD2 1 
ATOM   8073  C  CE1 . HIS B 1 245 ? 201.107 199.663 296.176 1.00 92.91  ? 245 HIS B CE1 1 
ATOM   8074  N  NE2 . HIS B 1 245 ? 200.406 198.784 295.483 1.00 92.91  ? 245 HIS B NE2 1 
ATOM   8075  N  N   . LEU B 1 246 ? 200.307 202.537 290.173 1.00 83.97  ? 246 LEU B N   1 
ATOM   8076  C  CA  . LEU B 1 246 ? 200.494 203.521 289.110 1.00 83.97  ? 246 LEU B CA  1 
ATOM   8077  C  C   . LEU B 1 246 ? 201.606 204.476 289.516 1.00 83.97  ? 246 LEU B C   1 
ATOM   8078  O  O   . LEU B 1 246 ? 201.411 205.362 290.348 1.00 83.97  ? 246 LEU B O   1 
ATOM   8079  C  CB  . LEU B 1 246 ? 199.197 204.269 288.843 1.00 83.97  ? 246 LEU B CB  1 
ATOM   8080  C  CG  . LEU B 1 246 ? 199.319 205.345 287.778 1.00 83.97  ? 246 LEU B CG  1 
ATOM   8081  C  CD1 . LEU B 1 246 ? 199.629 204.685 286.460 1.00 83.97  ? 246 LEU B CD1 1 
ATOM   8082  C  CD2 . LEU B 1 246 ? 198.041 206.140 287.686 1.00 83.97  ? 246 LEU B CD2 1 
ATOM   8083  N  N   . GLN B 1 247 ? 202.786 204.298 288.925 1.00 82.55  ? 247 GLN B N   1 
ATOM   8084  C  CA  . GLN B 1 247 ? 203.939 205.110 289.285 1.00 82.55  ? 247 GLN B CA  1 
ATOM   8085  C  C   . GLN B 1 247 ? 203.961 206.438 288.546 1.00 82.55  ? 247 GLN B C   1 
ATOM   8086  O  O   . GLN B 1 247 ? 203.975 207.496 289.183 1.00 82.55  ? 247 GLN B O   1 
ATOM   8087  C  CB  . GLN B 1 247 ? 205.234 204.348 289.005 1.00 82.55  ? 247 GLN B CB  1 
ATOM   8088  C  CG  . GLN B 1 247 ? 206.483 205.101 289.410 1.00 82.55  ? 247 GLN B CG  1 
ATOM   8089  C  CD  . GLN B 1 247 ? 206.475 205.493 290.869 1.00 82.55  ? 247 GLN B CD  1 
ATOM   8090  O  OE1 . GLN B 1 247 ? 206.275 206.658 291.209 1.00 82.55  ? 247 GLN B OE1 1 
ATOM   8091  N  NE2 . GLN B 1 247 ? 206.694 204.519 291.743 1.00 82.55  ? 247 GLN B NE2 1 
ATOM   8092  N  N   . ASN B 1 248 ? 203.965 206.409 287.216 1.00 76.35  ? 248 ASN B N   1 
ATOM   8093  C  CA  . ASN B 1 248 ? 204.023 207.638 286.438 1.00 76.35  ? 248 ASN B CA  1 
ATOM   8094  C  C   . ASN B 1 248 ? 203.222 207.457 285.156 1.00 76.35  ? 248 ASN B C   1 
ATOM   8095  O  O   . ASN B 1 248 ? 202.550 206.445 284.951 1.00 76.35  ? 248 ASN B O   1 
ATOM   8096  C  CB  . ASN B 1 248 ? 205.470 208.044 286.144 1.00 76.35  ? 248 ASN B CB  1 
ATOM   8097  C  CG  . ASN B 1 248 ? 206.068 208.910 287.237 1.00 76.35  ? 248 ASN B CG  1 
ATOM   8098  O  OD1 . ASN B 1 248 ? 207.125 208.599 287.781 1.00 76.35  ? 248 ASN B OD1 1 
ATOM   8099  N  ND2 . ASN B 1 248 ? 205.392 210.001 287.565 1.00 76.35  ? 248 ASN B ND2 1 
ATOM   8100  N  N   . LEU B 1 249 ? 203.306 208.458 284.288 1.00 76.12  ? 249 LEU B N   1 
ATOM   8101  C  CA  . LEU B 1 249 ? 202.426 208.543 283.134 1.00 76.12  ? 249 LEU B CA  1 
ATOM   8102  C  C   . LEU B 1 249 ? 203.090 209.428 282.089 1.00 76.12  ? 249 LEU B C   1 
ATOM   8103  O  O   . LEU B 1 249 ? 203.786 210.377 282.450 1.00 76.12  ? 249 LEU B O   1 
ATOM   8104  C  CB  . LEU B 1 249 ? 201.082 209.115 283.573 1.00 76.12  ? 249 LEU B CB  1 
ATOM   8105  C  CG  . LEU B 1 249 ? 199.946 209.198 282.571 1.00 76.12  ? 249 LEU B CG  1 
ATOM   8106  C  CD1 . LEU B 1 249 ? 199.156 207.906 282.561 1.00 76.12  ? 249 LEU B CD1 1 
ATOM   8107  C  CD2 . LEU B 1 249 ? 199.057 210.368 282.929 1.00 76.12  ? 249 LEU B CD2 1 
ATOM   8108  N  N   . VAL B 1 250 ? 202.881 209.129 280.809 1.00 67.81  ? 250 VAL B N   1 
ATOM   8109  C  CA  . VAL B 1 250 ? 203.479 209.898 279.722 1.00 67.81  ? 250 VAL B CA  1 
ATOM   8110  C  C   . VAL B 1 250 ? 202.392 210.336 278.749 1.00 67.81  ? 250 VAL B C   1 
ATOM   8111  O  O   . VAL B 1 250 ? 201.528 209.536 278.360 1.00 67.81  ? 250 VAL B O   1 
ATOM   8112  C  CB  . VAL B 1 250 ? 204.581 209.104 279.005 1.00 67.81  ? 250 VAL B CB  1 
ATOM   8113  C  CG1 . VAL B 1 250 ? 205.708 208.824 279.957 1.00 67.81  ? 250 VAL B CG1 1 
ATOM   8114  C  CG2 . VAL B 1 250 ? 204.036 207.804 278.456 1.00 67.81  ? 250 VAL B CG2 1 
ATOM   8115  N  N   . MET B 1 251 ? 202.425 211.616 278.382 1.00 68.29  ? 251 MET B N   1 
ATOM   8116  C  CA  . MET B 1 251 ? 201.559 212.185 277.356 1.00 68.29  ? 251 MET B CA  1 
ATOM   8117  C  C   . MET B 1 251 ? 202.434 212.703 276.228 1.00 68.29  ? 251 MET B C   1 
ATOM   8118  O  O   . MET B 1 251 ? 203.415 213.415 276.476 1.00 68.29  ? 251 MET B O   1 
ATOM   8119  C  CB  . MET B 1 251 ? 200.693 213.319 277.906 1.00 68.29  ? 251 MET B CB  1 
ATOM   8120  C  CG  . MET B 1 251 ? 199.598 212.877 278.845 1.00 68.29  ? 251 MET B CG  1 
ATOM   8121  S  SD  . MET B 1 251 ? 198.392 214.163 279.212 1.00 68.29  ? 251 MET B SD  1 
ATOM   8122  C  CE  . MET B 1 251 ? 197.462 214.202 277.683 1.00 68.29  ? 251 MET B CE  1 
ATOM   8123  N  N   . THR B 1 252 ? 202.078 212.356 274.994 1.00 62.18  ? 252 THR B N   1 
ATOM   8124  C  CA  . THR B 1 252 ? 202.831 212.777 273.816 1.00 62.18  ? 252 THR B CA  1 
ATOM   8125  C  C   . THR B 1 252 ? 201.907 213.568 272.900 1.00 62.18  ? 252 THR B C   1 
ATOM   8126  O  O   . THR B 1 252 ? 201.274 213.010 272.001 1.00 62.18  ? 252 THR B O   1 
ATOM   8127  C  CB  . THR B 1 252 ? 203.433 211.589 273.093 1.00 62.18  ? 252 THR B CB  1 
ATOM   8128  O  OG1 . THR B 1 252 ? 202.383 210.749 272.603 1.00 62.18  ? 252 THR B OG1 1 
ATOM   8129  C  CG2 . THR B 1 252 ? 204.310 210.796 274.034 1.00 62.18  ? 252 THR B CG2 1 
ATOM   8130  N  N   . PHE B 1 253 ? 201.836 214.873 273.130 1.00 65.60  ? 253 PHE B N   1 
ATOM   8131  C  CA  . PHE B 1 253 ? 201.113 215.743 272.225 1.00 65.60  ? 253 PHE B CA  1 
ATOM   8132  C  C   . PHE B 1 253 ? 201.767 215.722 270.847 1.00 65.60  ? 253 PHE B C   1 
ATOM   8133  O  O   . PHE B 1 253 ? 202.990 215.708 270.704 1.00 65.60  ? 253 PHE B O   1 
ATOM   8134  C  CB  . PHE B 1 253 ? 201.077 217.171 272.767 1.00 65.60  ? 253 PHE B CB  1 
ATOM   8135  C  CG  . PHE B 1 253 ? 200.663 217.264 274.205 1.00 65.60  ? 253 PHE B CG  1 
ATOM   8136  C  CD1 . PHE B 1 253 ? 199.359 216.999 274.581 1.00 65.60  ? 253 PHE B CD1 1 
ATOM   8137  C  CD2 . PHE B 1 253 ? 201.573 217.630 275.179 1.00 65.60  ? 253 PHE B CD2 1 
ATOM   8138  C  CE1 . PHE B 1 253 ? 198.975 217.086 275.901 1.00 65.60  ? 253 PHE B CE1 1 
ATOM   8139  C  CE2 . PHE B 1 253 ? 201.193 217.720 276.499 1.00 65.60  ? 253 PHE B CE2 1 
ATOM   8140  C  CZ  . PHE B 1 253 ? 199.894 217.447 276.861 1.00 65.60  ? 253 PHE B CZ  1 
ATOM   8141  N  N   . SER B 1 254 ? 200.928 215.703 269.821 1.00 66.75  ? 254 SER B N   1 
ATOM   8142  C  CA  . SER B 1 254 ? 201.418 215.756 268.453 1.00 66.75  ? 254 SER B CA  1 
ATOM   8143  C  C   . SER B 1 254 ? 200.504 216.657 267.642 1.00 66.75  ? 254 SER B C   1 
ATOM   8144  O  O   . SER B 1 254 ? 199.279 216.588 267.776 1.00 66.75  ? 254 SER B O   1 
ATOM   8145  C  CB  . SER B 1 254 ? 201.491 214.361 267.824 1.00 66.75  ? 254 SER B CB  1 
ATOM   8146  O  OG  . SER B 1 254 ? 200.199 213.847 267.566 1.00 66.75  ? 254 SER B OG  1 
ATOM   8147  N  N   . ASP B 1 255 ? 201.107 217.497 266.810 1.00 65.96  ? 255 ASP B N   1 
ATOM   8148  C  CA  . ASP B 1 255 ? 200.344 218.437 266.007 1.00 65.96  ? 255 ASP B CA  1 
ATOM   8149  C  C   . ASP B 1 255 ? 199.710 217.731 264.816 1.00 65.96  ? 255 ASP B C   1 
ATOM   8150  O  O   . ASP B 1 255 ? 200.144 216.652 264.404 1.00 65.96  ? 255 ASP B O   1 
ATOM   8151  C  CB  . ASP B 1 255 ? 201.241 219.574 265.526 1.00 65.96  ? 255 ASP B CB  1 
ATOM   8152  C  CG  . ASP B 1 255 ? 200.459 220.806 265.136 1.00 65.96  ? 255 ASP B CG  1 
ATOM   8153  O  OD1 . ASP B 1 255 ? 199.226 220.703 264.972 1.00 65.96  ? 255 ASP B OD1 1 
ATOM   8154  O  OD2 . ASP B 1 255 ? 201.076 221.883 265.003 1.00 65.96  ? 255 ASP B OD2 1 
ATOM   8155  N  N   . ILE B 1 256 ? 198.661 218.345 264.272 1.00 64.77  ? 256 ILE B N   1 
ATOM   8156  C  CA  . ILE B 1 256 ? 197.984 217.814 263.103 1.00 64.77  ? 256 ILE B CA  1 
ATOM   8157  C  C   . ILE B 1 256 ? 198.071 218.754 261.906 1.00 64.77  ? 256 ILE B C   1 
ATOM   8158  O  O   . ILE B 1 256 ? 198.204 218.282 260.766 1.00 64.77  ? 256 ILE B O   1 
ATOM   8159  C  CB  . ILE B 1 256 ? 196.514 217.482 263.426 1.00 64.77  ? 256 ILE B CB  1 
ATOM   8160  C  CG1 . ILE B 1 256 ? 196.415 216.743 264.758 1.00 64.77  ? 256 ILE B CG1 1 
ATOM   8161  C  CG2 . ILE B 1 256 ? 195.899 216.655 262.314 1.00 64.77  ? 256 ILE B CG2 1 
ATOM   8162  C  CD1 . ILE B 1 256 ? 195.025 216.273 265.087 1.00 64.77  ? 256 ILE B CD1 1 
ATOM   8163  N  N   . THR B 1 257 ? 197.979 220.067 262.131 1.00 64.20  ? 257 THR B N   1 
ATOM   8164  C  CA  . THR B 1 257 ? 198.143 221.019 261.043 1.00 64.20  ? 257 THR B CA  1 
ATOM   8165  C  C   . THR B 1 257 ? 199.505 220.861 260.387 1.00 64.20  ? 257 THR B C   1 
ATOM   8166  O  O   . THR B 1 257 ? 199.634 220.995 259.165 1.00 64.20  ? 257 THR B O   1 
ATOM   8167  C  CB  . THR B 1 257 ? 197.960 222.441 261.564 1.00 64.20  ? 257 THR B CB  1 
ATOM   8168  O  OG1 . THR B 1 257 ? 196.742 222.518 262.314 1.00 64.20  ? 257 THR B OG1 1 
ATOM   8169  C  CG2 . THR B 1 257 ? 197.895 223.425 260.410 1.00 64.20  ? 257 THR B CG2 1 
ATOM   8170  N  N   . GLU B 1 258 ? 200.530 220.548 261.181 1.00 64.54  ? 258 GLU B N   1 
ATOM   8171  C  CA  . GLU B 1 258 ? 201.865 220.349 260.630 1.00 64.54  ? 258 GLU B CA  1 
ATOM   8172  C  C   . GLU B 1 258 ? 201.883 219.199 259.632 1.00 64.54  ? 258 GLU B C   1 
ATOM   8173  O  O   . GLU B 1 258 ? 202.427 219.328 258.530 1.00 64.54  ? 258 GLU B O   1 
ATOM   8174  C  CB  . GLU B 1 258 ? 202.863 220.096 261.758 1.00 64.54  ? 258 GLU B CB  1 
ATOM   8175  C  CG  . GLU B 1 258 ? 203.173 221.323 262.597 1.00 64.54  ? 258 GLU B CG  1 
ATOM   8176  C  CD  . GLU B 1 258 ? 204.173 221.036 263.698 1.00 64.54  ? 258 GLU B CD  1 
ATOM   8177  O  OE1 . GLU B 1 258 ? 204.522 219.852 263.894 1.00 64.54  ? 258 GLU B OE1 1 
ATOM   8178  O  OE2 . GLU B 1 258 ? 204.612 221.993 264.369 1.00 64.54  ? 258 GLU B OE2 1 
ATOM   8179  N  N   . GLU B 1 259 ? 201.289 218.064 259.999 1.00 63.71  ? 259 GLU B N   1 
ATOM   8180  C  CA  . GLU B 1 259 ? 201.301 216.909 259.108 1.00 63.71  ? 259 GLU B CA  1 
ATOM   8181  C  C   . GLU B 1 259 ? 200.473 217.162 257.859 1.00 63.71  ? 259 GLU B C   1 
ATOM   8182  O  O   . GLU B 1 259 ? 200.875 216.781 256.749 1.00 63.71  ? 259 GLU B O   1 
ATOM   8183  C  CB  . GLU B 1 259 ? 200.805 215.672 259.851 1.00 63.71  ? 259 GLU B CB  1 
ATOM   8184  C  CG  . GLU B 1 259 ? 201.888 214.950 260.638 1.00 63.71  ? 259 GLU B CG  1 
ATOM   8185  C  CD  . GLU B 1 259 ? 202.309 215.686 261.897 1.00 63.71  ? 259 GLU B CD  1 
ATOM   8186  O  OE1 . GLU B 1 259 ? 201.783 216.786 262.161 1.00 63.71  ? 259 GLU B OE1 1 
ATOM   8187  O  OE2 . GLU B 1 259 ? 203.173 215.157 262.628 1.00 63.71  ? 259 GLU B OE2 1 
ATOM   8188  N  N   . ARG B 1 260 ? 199.316 217.809 258.014 1.00 60.70  ? 260 ARG B N   1 
ATOM   8189  C  CA  . ARG B 1 260 ? 198.513 218.127 256.838 1.00 60.70  ? 260 ARG B CA  1 
ATOM   8190  C  C   . ARG B 1 260 ? 199.275 219.045 255.889 1.00 60.70  ? 260 ARG B C   1 
ATOM   8191  O  O   . ARG B 1 260 ? 199.283 218.828 254.670 1.00 60.70  ? 260 ARG B O   1 
ATOM   8192  C  CB  . ARG B 1 260 ? 197.191 218.759 257.258 1.00 60.70  ? 260 ARG B CB  1 
ATOM   8193  C  CG  . ARG B 1 260 ? 196.220 218.970 256.115 1.00 60.70  ? 260 ARG B CG  1 
ATOM   8194  C  CD  . ARG B 1 260 ? 194.885 219.483 256.625 1.00 60.70  ? 260 ARG B CD  1 
ATOM   8195  N  NE  . ARG B 1 260 ? 194.212 218.498 257.463 1.00 60.70  ? 260 ARG B NE  1 
ATOM   8196  C  CZ  . ARG B 1 260 ? 193.998 218.644 258.763 1.00 60.70  ? 260 ARG B CZ  1 
ATOM   8197  N  NH1 . ARG B 1 260 ? 194.393 219.727 259.412 1.00 60.70  ? 260 ARG B NH1 1 
ATOM   8198  N  NH2 . ARG B 1 260 ? 193.372 217.678 259.430 1.00 60.70  ? 260 ARG B NH2 1 
ATOM   8199  N  N   . GLN B 1 261 ? 199.952 220.056 256.435 1.00 60.42  ? 261 GLN B N   1 
ATOM   8200  C  CA  . GLN B 1 261 ? 200.718 220.971 255.599 1.00 60.42  ? 261 GLN B CA  1 
ATOM   8201  C  C   . GLN B 1 261 ? 201.895 220.268 254.933 1.00 60.42  ? 261 GLN B C   1 
ATOM   8202  O  O   . GLN B 1 261 ? 202.235 220.580 253.788 1.00 60.42  ? 261 GLN B O   1 
ATOM   8203  C  CB  . GLN B 1 261 ? 201.198 222.159 256.430 1.00 60.42  ? 261 GLN B CB  1 
ATOM   8204  C  CG  . GLN B 1 261 ? 200.086 223.084 256.896 1.00 60.42  ? 261 GLN B CG  1 
ATOM   8205  C  CD  . GLN B 1 261 ? 199.650 224.065 255.828 1.00 60.42  ? 261 GLN B CD  1 
ATOM   8206  O  OE1 . GLN B 1 261 ? 200.081 223.984 254.678 1.00 60.42  ? 261 GLN B OE1 1 
ATOM   8207  N  NE2 . GLN B 1 261 ? 198.787 225.002 256.204 1.00 60.42  ? 261 GLN B NE2 1 
ATOM   8208  N  N   . ILE B 1 262 ? 202.538 219.328 255.630 1.00 54.18  ? 262 ILE B N   1 
ATOM   8209  C  CA  . ILE B 1 262 ? 203.661 218.608 255.032 1.00 54.18  ? 262 ILE B CA  1 
ATOM   8210  C  C   . ILE B 1 262 ? 203.193 217.753 253.860 1.00 54.18  ? 262 ILE B C   1 
ATOM   8211  O  O   . ILE B 1 262 ? 203.837 217.715 252.800 1.00 54.18  ? 262 ILE B O   1 
ATOM   8212  C  CB  . ILE B 1 262 ? 204.380 217.767 256.095 1.00 54.18  ? 262 ILE B CB  1 
ATOM   8213  C  CG1 . ILE B 1 262 ? 205.136 218.674 257.049 1.00 54.18  ? 262 ILE B CG1 1 
ATOM   8214  C  CG2 . ILE B 1 262 ? 205.335 216.802 255.445 1.00 54.18  ? 262 ILE B CG2 1 
ATOM   8215  C  CD1 . ILE B 1 262 ? 206.343 219.301 256.430 1.00 54.18  ? 262 ILE B CD1 1 
ATOM   8216  N  N   . ARG B 1 263 ? 202.070 217.050 254.027 1.00 57.54  ? 263 ARG B N   1 
ATOM   8217  C  CA  . ARG B 1 263 ? 201.532 216.274 252.913 1.00 57.54  ? 263 ARG B CA  1 
ATOM   8218  C  C   . ARG B 1 263 ? 201.155 217.178 251.746 1.00 57.54  ? 263 ARG B C   1 
ATOM   8219  O  O   . ARG B 1 263 ? 201.408 216.843 250.580 1.00 57.54  ? 263 ARG B O   1 
ATOM   8220  C  CB  . ARG B 1 263 ? 200.326 215.454 253.365 1.00 57.54  ? 263 ARG B CB  1 
ATOM   8221  C  CG  . ARG B 1 263 ? 200.677 214.298 254.275 1.00 57.54  ? 263 ARG B CG  1 
ATOM   8222  C  CD  . ARG B 1 263 ? 199.431 213.612 254.796 1.00 57.54  ? 263 ARG B CD  1 
ATOM   8223  N  NE  . ARG B 1 263 ? 198.665 212.984 253.727 1.00 57.54  ? 263 ARG B NE  1 
ATOM   8224  C  CZ  . ARG B 1 263 ? 197.471 213.396 253.322 1.00 57.54  ? 263 ARG B CZ  1 
ATOM   8225  N  NH1 . ARG B 1 263 ? 196.877 214.441 253.874 1.00 57.54  ? 263 ARG B NH1 1 
ATOM   8226  N  NH2 . ARG B 1 263 ? 196.858 212.742 252.339 1.00 57.54  ? 263 ARG B NH2 1 
ATOM   8227  N  N   . GLN B 1 264 ? 200.560 218.333 252.040 1.00 54.72  ? 264 GLN B N   1 
ATOM   8228  C  CA  . GLN B 1 264 ? 200.221 219.267 250.975 1.00 54.72  ? 264 GLN B CA  1 
ATOM   8229  C  C   . GLN B 1 264 ? 201.471 219.759 250.258 1.00 54.72  ? 264 GLN B C   1 
ATOM   8230  O  O   . GLN B 1 264 ? 201.469 219.923 249.033 1.00 54.72  ? 264 GLN B O   1 
ATOM   8231  C  CB  . GLN B 1 264 ? 199.424 220.438 251.544 1.00 54.72  ? 264 GLN B CB  1 
ATOM   8232  C  CG  . GLN B 1 264 ? 198.450 221.055 250.563 1.00 54.72  ? 264 GLN B CG  1 
ATOM   8233  C  CD  . GLN B 1 264 ? 197.687 222.215 251.163 1.00 54.72  ? 264 GLN B CD  1 
ATOM   8234  O  OE1 . GLN B 1 264 ? 198.264 223.070 251.833 1.00 54.72  ? 264 GLN B OE1 1 
ATOM   8235  N  NE2 . GLN B 1 264 ? 196.382 222.251 250.925 1.00 54.72  ? 264 GLN B NE2 1 
ATOM   8236  N  N   . LEU B 1 265 ? 202.547 220.008 251.006 1.00 49.20  ? 265 LEU B N   1 
ATOM   8237  C  CA  . LEU B 1 265 ? 203.787 220.471 250.392 1.00 49.20  ? 265 LEU B CA  1 
ATOM   8238  C  C   . LEU B 1 265 ? 204.358 219.418 249.456 1.00 49.20  ? 265 LEU B C   1 
ATOM   8239  O  O   . LEU B 1 265 ? 204.775 219.729 248.332 1.00 49.20  ? 265 LEU B O   1 
ATOM   8240  C  CB  . LEU B 1 265 ? 204.802 220.846 251.471 1.00 49.20  ? 265 LEU B CB  1 
ATOM   8241  C  CG  . LEU B 1 265 ? 206.253 220.948 251.004 1.00 49.20  ? 265 LEU B CG  1 
ATOM   8242  C  CD1 . LEU B 1 265 ? 206.436 222.094 250.049 1.00 49.20  ? 265 LEU B CD1 1 
ATOM   8243  C  CD2 . LEU B 1 265 ? 207.173 221.098 252.190 1.00 49.20  ? 265 LEU B CD2 1 
ATOM   8244  N  N   . GLU B 1 266 ? 204.381 218.161 249.900 1.00 52.58  ? 266 GLU B N   1 
ATOM   8245  C  CA  . GLU B 1 266 ? 204.849 217.095 249.019 1.00 52.58  ? 266 GLU B CA  1 
ATOM   8246  C  C   . GLU B 1 266 ? 204.007 217.030 247.755 1.00 52.58  ? 266 GLU B C   1 
ATOM   8247  O  O   . GLU B 1 266 ? 204.544 216.962 246.641 1.00 52.58  ? 266 GLU B O   1 
ATOM   8248  C  CB  . GLU B 1 266 ? 204.810 215.746 249.733 1.00 52.58  ? 266 GLU B CB  1 
ATOM   8249  C  CG  . GLU B 1 266 ? 205.857 215.545 250.804 1.00 52.58  ? 266 GLU B CG  1 
ATOM   8250  C  CD  . GLU B 1 266 ? 205.736 214.187 251.470 1.00 52.58  ? 266 GLU B CD  1 
ATOM   8251  O  OE1 . GLU B 1 266 ? 204.747 213.477 251.195 1.00 52.58  ? 266 GLU B OE1 1 
ATOM   8252  O  OE2 . GLU B 1 266 ? 206.628 213.829 252.265 1.00 52.58  ? 266 GLU B OE2 1 
ATOM   8253  N  N   . GLY B 1 267 ? 202.685 217.056 247.910 1.00 52.82  ? 267 GLY B N   1 
ATOM   8254  C  CA  . GLY B 1 267 ? 201.820 216.956 246.748 1.00 52.82  ? 267 GLY B CA  1 
ATOM   8255  C  C   . GLY B 1 267 ? 202.046 218.085 245.762 1.00 52.82  ? 267 GLY B C   1 
ATOM   8256  O  O   . GLY B 1 267 ? 202.146 217.861 244.555 1.00 52.82  ? 267 GLY B O   1 
ATOM   8257  N  N   . ASN B 1 268 ? 202.144 219.314 246.268 1.00 49.25  ? 268 ASN B N   1 
ATOM   8258  C  CA  . ASN B 1 268 ? 202.327 220.460 245.389 1.00 49.25  ? 268 ASN B CA  1 
ATOM   8259  C  C   . ASN B 1 268 ? 203.669 220.411 244.678 1.00 49.25  ? 268 ASN B C   1 
ATOM   8260  O  O   . ASN B 1 268 ? 203.749 220.694 243.475 1.00 49.25  ? 268 ASN B O   1 
ATOM   8261  C  CB  . ASN B 1 268 ? 202.191 221.749 246.190 1.00 49.25  ? 268 ASN B CB  1 
ATOM   8262  C  CG  . ASN B 1 268 ? 200.788 221.970 246.681 1.00 49.25  ? 268 ASN B CG  1 
ATOM   8263  O  OD1 . ASN B 1 268 ? 199.893 221.178 246.397 1.00 49.25  ? 268 ASN B OD1 1 
ATOM   8264  N  ND2 . ASN B 1 268 ? 200.583 223.045 247.429 1.00 49.25  ? 268 ASN B ND2 1 
ATOM   8265  N  N   . ILE B 1 269 ? 204.737 220.060 245.398 1.00 49.36  ? 269 ILE B N   1 
ATOM   8266  C  CA  . ILE B 1 269 ? 206.047 220.022 244.761 1.00 49.36  ? 269 ILE B CA  1 
ATOM   8267  C  C   . ILE B 1 269 ? 206.072 218.974 243.663 1.00 49.36  ? 269 ILE B C   1 
ATOM   8268  O  O   . ILE B 1 269 ? 206.569 219.229 242.560 1.00 49.36  ? 269 ILE B O   1 
ATOM   8269  C  CB  . ILE B 1 269 ? 207.157 219.782 245.792 1.00 49.36  ? 269 ILE B CB  1 
ATOM   8270  C  CG1 . ILE B 1 269 ? 207.308 221.007 246.684 1.00 49.36  ? 269 ILE B CG1 1 
ATOM   8271  C  CG2 . ILE B 1 269 ? 208.459 219.521 245.086 1.00 49.36  ? 269 ILE B CG2 1 
ATOM   8272  C  CD1 . ILE B 1 269 ? 207.913 222.183 245.978 1.00 49.36  ? 269 ILE B CD1 1 
ATOM   8273  N  N   . LEU B 1 270 ? 205.528 217.783 243.932 1.00 49.56  ? 270 LEU B N   1 
ATOM   8274  C  CA  . LEU B 1 270 ? 205.510 216.766 242.885 1.00 49.56  ? 270 LEU B CA  1 
ATOM   8275  C  C   . LEU B 1 270 ? 204.631 217.187 241.721 1.00 49.56  ? 270 LEU B C   1 
ATOM   8276  O  O   . LEU B 1 270 ? 204.989 216.970 240.559 1.00 49.56  ? 270 LEU B O   1 
ATOM   8277  C  CB  . LEU B 1 270 ? 205.048 215.417 243.426 1.00 49.56  ? 270 LEU B CB  1 
ATOM   8278  C  CG  . LEU B 1 270 ? 206.118 214.543 244.077 1.00 49.56  ? 270 LEU B CG  1 
ATOM   8279  C  CD1 . LEU B 1 270 ? 207.213 214.229 243.079 1.00 49.56  ? 270 LEU B CD1 1 
ATOM   8280  C  CD2 . LEU B 1 270 ? 206.673 215.152 245.333 1.00 49.56  ? 270 LEU B CD2 1 
ATOM   8281  N  N   . ALA B 1 271 ? 203.479 217.794 242.006 1.00 53.00  ? 271 ALA B N   1 
ATOM   8282  C  CA  . ALA B 1 271 ? 202.569 218.192 240.938 1.00 53.00  ? 271 ALA B CA  1 
ATOM   8283  C  C   . ALA B 1 271 ? 203.227 219.197 240.007 1.00 53.00  ? 271 ALA B C   1 
ATOM   8284  O  O   . ALA B 1 271 ? 203.096 219.107 238.783 1.00 53.00  ? 271 ALA B O   1 
ATOM   8285  C  CB  . ALA B 1 271 ? 201.286 218.766 241.534 1.00 53.00  ? 271 ALA B CB  1 
ATOM   8286  N  N   . ALA B 1 272 ? 203.940 220.167 240.573 1.00 53.57  ? 272 ALA B N   1 
ATOM   8287  C  CA  . ALA B 1 272 ? 204.643 221.132 239.739 1.00 53.57  ? 272 ALA B CA  1 
ATOM   8288  C  C   . ALA B 1 272 ? 205.796 220.477 238.992 1.00 53.57  ? 272 ALA B C   1 
ATOM   8289  O  O   . ALA B 1 272 ? 205.975 220.700 237.790 1.00 53.57  ? 272 ALA B O   1 
ATOM   8290  C  CB  . ALA B 1 272 ? 205.145 222.293 240.593 1.00 53.57  ? 272 ALA B CB  1 
ATOM   8291  N  N   . MET B 1 273 ? 206.585 219.653 239.684 1.00 53.64  ? 273 MET B N   1 
ATOM   8292  C  CA  . MET B 1 273 ? 207.799 219.117 239.083 1.00 53.64  ? 273 MET B CA  1 
ATOM   8293  C  C   . MET B 1 273 ? 207.493 218.135 237.963 1.00 53.64  ? 273 MET B C   1 
ATOM   8294  O  O   . MET B 1 273 ? 208.285 218.003 237.023 1.00 53.64  ? 273 MET B O   1 
ATOM   8295  C  CB  . MET B 1 273 ? 208.660 218.452 240.154 1.00 53.64  ? 273 MET B CB  1 
ATOM   8296  C  CG  . MET B 1 273 ? 210.065 218.129 239.711 1.00 53.64  ? 273 MET B CG  1 
ATOM   8297  S  SD  . MET B 1 273 ? 210.940 217.131 240.923 1.00 53.64  ? 273 MET B SD  1 
ATOM   8298  C  CE  . MET B 1 273 ? 211.205 218.344 242.207 1.00 53.64  ? 273 MET B CE  1 
ATOM   8299  N  N   . CYS B 1 274 ? 206.359 217.437 238.037 1.00 57.72  ? 274 CYS B N   1 
ATOM   8300  C  CA  . CYS B 1 274 ? 206.062 216.430 237.027 1.00 57.72  ? 274 CYS B CA  1 
ATOM   8301  C  C   . CYS B 1 274 ? 205.765 217.056 235.672 1.00 57.72  ? 274 CYS B C   1 
ATOM   8302  O  O   . CYS B 1 274 ? 205.836 216.368 234.648 1.00 57.72  ? 274 CYS B O   1 
ATOM   8303  C  CB  . CYS B 1 274 ? 204.878 215.572 237.467 1.00 57.72  ? 274 CYS B CB  1 
ATOM   8304  S  SG  . CYS B 1 274 ? 205.173 214.460 238.855 1.00 57.72  ? 274 CYS B SG  1 
ATOM   8305  N  N   . SER B 1 275 ? 205.438 218.347 235.637 1.00 59.44  ? 275 SER B N   1 
ATOM   8306  C  CA  . SER B 1 275 ? 205.152 219.014 234.372 1.00 59.44  ? 275 SER B CA  1 
ATOM   8307  C  C   . SER B 1 275 ? 206.408 219.474 233.646 1.00 59.44  ? 275 SER B C   1 
ATOM   8308  O  O   . SER B 1 275 ? 206.293 220.065 232.569 1.00 59.44  ? 275 SER B O   1 
ATOM   8309  C  CB  . SER B 1 275 ? 204.227 220.208 234.600 1.00 59.44  ? 275 SER B CB  1 
ATOM   8310  O  OG  . SER B 1 275 ? 204.932 221.293 235.174 1.00 59.44  ? 275 SER B OG  1 
ATOM   8311  N  N   . SER B 1 276 ? 207.588 219.223 234.209 1.00 62.22  ? 276 SER B N   1 
ATOM   8312  C  CA  . SER B 1 276 ? 208.880 219.564 233.625 1.00 62.22  ? 276 SER B CA  1 
ATOM   8313  C  C   . SER B 1 276 ? 208.987 221.060 233.367 1.00 62.22  ? 276 SER B C   1 
ATOM   8314  O  O   . SER B 1 276 ? 209.012 221.489 232.208 1.00 62.22  ? 276 SER B O   1 
ATOM   8315  C  CB  . SER B 1 276 ? 209.118 218.786 232.330 1.00 62.22  ? 276 SER B CB  1 
ATOM   8316  O  OG  . SER B 1 276 ? 208.214 219.182 231.313 1.00 62.22  ? 276 SER B OG  1 
ATOM   8317  N  N   . PRO B 1 277 ? 209.056 221.882 234.409 1.00 63.32  ? 277 PRO B N   1 
ATOM   8318  C  CA  . PRO B 1 277 ? 209.238 223.310 234.206 1.00 63.32  ? 277 PRO B CA  1 
ATOM   8319  C  C   . PRO B 1 277 ? 210.698 223.618 233.941 1.00 63.32  ? 277 PRO B C   1 
ATOM   8320  O  O   . PRO B 1 277 ? 211.556 222.733 234.072 1.00 63.32  ? 277 PRO B O   1 
ATOM   8321  C  CB  . PRO B 1 277 ? 208.768 223.920 235.535 1.00 63.32  ? 277 PRO B CB  1 
ATOM   8322  C  CG  . PRO B 1 277 ? 208.785 222.792 236.534 1.00 63.32  ? 277 PRO B CG  1 
ATOM   8323  C  CD  . PRO B 1 277 ? 209.150 221.518 235.831 1.00 63.32  ? 277 PRO B CD  1 
ATOM   8324  N  N   . PRO B 1 278 ? 211.023 224.844 233.546 1.00 63.90  ? 278 PRO B N   1 
ATOM   8325  C  CA  . PRO B 1 278 ? 212.430 225.236 233.465 1.00 63.90  ? 278 PRO B CA  1 
ATOM   8326  C  C   . PRO B 1 278 ? 213.066 225.295 234.843 1.00 63.90  ? 278 PRO B C   1 
ATOM   8327  O  O   . PRO B 1 278 ? 212.386 225.425 235.864 1.00 63.90  ? 278 PRO B O   1 
ATOM   8328  C  CB  . PRO B 1 278 ? 212.378 226.625 232.818 1.00 63.90  ? 278 PRO B CB  1 
ATOM   8329  C  CG  . PRO B 1 278 ? 211.000 227.109 233.057 1.00 63.90  ? 278 PRO B CG  1 
ATOM   8330  C  CD  . PRO B 1 278 ? 210.128 225.900 233.047 1.00 63.90  ? 278 PRO B CD  1 
ATOM   8331  N  N   . PHE B 1 279 ? 214.395 225.188 234.851 1.00 62.67  ? 279 PHE B N   1 
ATOM   8332  C  CA  . PHE B 1 279 ? 215.160 225.138 236.091 1.00 62.67  ? 279 PHE B CA  1 
ATOM   8333  C  C   . PHE B 1 279 ? 214.815 226.287 237.033 1.00 62.67  ? 279 PHE B C   1 
ATOM   8334  O  O   . PHE B 1 279 ? 214.523 226.079 238.220 1.00 62.67  ? 279 PHE B O   1 
ATOM   8335  C  CB  . PHE B 1 279 ? 216.649 225.162 235.743 1.00 62.67  ? 279 PHE B CB  1 
ATOM   8336  C  CG  . PHE B 1 279 ? 217.559 224.880 236.905 1.00 62.67  ? 279 PHE B CG  1 
ATOM   8337  C  CD1 . PHE B 1 279 ? 217.812 223.584 237.305 1.00 62.67  ? 279 PHE B CD1 1 
ATOM   8338  C  CD2 . PHE B 1 279 ? 218.173 225.912 237.584 1.00 62.67  ? 279 PHE B CD2 1 
ATOM   8339  C  CE1 . PHE B 1 279 ? 218.650 223.329 238.360 1.00 62.67  ? 279 PHE B CE1 1 
ATOM   8340  C  CE2 . PHE B 1 279 ? 219.012 225.656 238.638 1.00 62.67  ? 279 PHE B CE2 1 
ATOM   8341  C  CZ  . PHE B 1 279 ? 219.249 224.365 239.026 1.00 62.67  ? 279 PHE B CZ  1 
ATOM   8342  N  N   . HIS B 1 280 ? 214.838 227.510 236.511 1.00 65.52  ? 280 HIS B N   1 
ATOM   8343  C  CA  . HIS B 1 280 ? 214.590 228.680 237.337 1.00 65.52  ? 280 HIS B CA  1 
ATOM   8344  C  C   . HIS B 1 280 ? 213.119 228.861 237.675 1.00 65.52  ? 280 HIS B C   1 
ATOM   8345  O  O   . HIS B 1 280 ? 212.794 229.723 238.497 1.00 65.52  ? 280 HIS B O   1 
ATOM   8346  C  CB  . HIS B 1 280 ? 215.139 229.925 236.643 1.00 65.52  ? 280 HIS B CB  1 
ATOM   8347  C  CG  . HIS B 1 280 ? 216.634 229.990 236.630 1.00 65.52  ? 280 HIS B CG  1 
ATOM   8348  N  ND1 . HIS B 1 280 ? 217.408 229.173 235.833 1.00 65.52  ? 280 HIS B ND1 1 
ATOM   8349  C  CD2 . HIS B 1 280 ? 217.499 230.768 237.322 1.00 65.52  ? 280 HIS B CD2 1 
ATOM   8350  C  CE1 . HIS B 1 280 ? 218.684 229.449 236.033 1.00 65.52  ? 280 HIS B CE1 1 
ATOM   8351  N  NE2 . HIS B 1 280 ? 218.767 230.413 236.932 1.00 65.52  ? 280 HIS B NE2 1 
ATOM   8352  N  N   . GLU B 1 281 ? 212.228 228.090 237.058 1.00 68.66  ? 281 GLU B N   1 
ATOM   8353  C  CA  . GLU B 1 281 ? 210.843 228.066 237.504 1.00 68.66  ? 281 GLU B CA  1 
ATOM   8354  C  C   . GLU B 1 281 ? 210.638 227.045 238.612 1.00 68.66  ? 281 GLU B C   1 
ATOM   8355  O  O   . GLU B 1 281 ? 209.872 227.290 239.550 1.00 68.66  ? 281 GLU B O   1 
ATOM   8356  C  CB  . GLU B 1 281 ? 209.910 227.762 236.331 1.00 68.66  ? 281 GLU B CB  1 
ATOM   8357  C  CG  . GLU B 1 281 ? 208.438 227.671 236.707 1.00 68.66  ? 281 GLU B CG  1 
ATOM   8358  C  CD  . GLU B 1 281 ? 207.796 229.031 236.904 1.00 68.66  ? 281 GLU B CD  1 
ATOM   8359  O  OE1 . GLU B 1 281 ? 208.479 230.054 236.689 1.00 68.66  ? 281 GLU B OE1 1 
ATOM   8360  O  OE2 . GLU B 1 281 ? 206.604 229.077 237.276 1.00 68.66  ? 281 GLU B OE2 1 
ATOM   8361  N  N   . MET B 1 282 ? 211.325 225.903 238.526 1.00 67.97  ? 282 MET B N   1 
ATOM   8362  C  CA  . MET B 1 282 ? 211.247 224.914 239.594 1.00 67.97  ? 282 MET B CA  1 
ATOM   8363  C  C   . MET B 1 282 ? 211.844 225.455 240.883 1.00 67.97  ? 282 MET B C   1 
ATOM   8364  O  O   . MET B 1 282 ? 211.318 225.205 241.976 1.00 67.97  ? 282 MET B O   1 
ATOM   8365  C  CB  . MET B 1 282 ? 211.955 223.628 239.179 1.00 67.97  ? 282 MET B CB  1 
ATOM   8366  C  CG  . MET B 1 282 ? 211.676 222.474 240.111 1.00 67.97  ? 282 MET B CG  1 
ATOM   8367  S  SD  . MET B 1 282 ? 209.916 222.085 240.151 1.00 67.97  ? 282 MET B SD  1 
ATOM   8368  C  CE  . MET B 1 282 ? 209.703 221.628 241.869 1.00 67.97  ? 282 MET B CE  1 
ATOM   8369  N  N   . GLY B 1 283 ? 212.956 226.185 240.777 1.00 65.38  ? 283 GLY B N   1 
ATOM   8370  C  CA  . GLY B 1 283 ? 213.514 226.814 241.963 1.00 65.38  ? 283 GLY B CA  1 
ATOM   8371  C  C   . GLY B 1 283 ? 212.516 227.732 242.639 1.00 65.38  ? 283 GLY B C   1 
ATOM   8372  O  O   . GLY B 1 283 ? 212.336 227.695 243.862 1.00 65.38  ? 283 GLY B O   1 
ATOM   8373  N  N   . GLU B 1 284 ? 211.829 228.551 241.844 1.00 68.45  ? 284 GLU B N   1 
ATOM   8374  C  CA  . GLU B 1 284 ? 210.833 229.453 242.401 1.00 68.45  ? 284 GLU B CA  1 
ATOM   8375  C  C   . GLU B 1 284 ? 209.650 228.691 242.976 1.00 68.45  ? 284 GLU B C   1 
ATOM   8376  O  O   . GLU B 1 284 ? 209.069 229.122 243.975 1.00 68.45  ? 284 GLU B O   1 
ATOM   8377  C  CB  . GLU B 1 284 ? 210.365 230.444 241.337 1.00 68.45  ? 284 GLU B CB  1 
ATOM   8378  C  CG  . GLU B 1 284 ? 209.290 231.406 241.814 1.00 68.45  ? 284 GLU B CG  1 
ATOM   8379  C  CD  . GLU B 1 284 ? 209.777 232.322 242.918 1.00 68.45  ? 284 GLU B CD  1 
ATOM   8380  O  OE1 . GLU B 1 284 ? 210.992 232.609 242.965 1.00 68.45  ? 284 GLU B OE1 1 
ATOM   8381  O  OE2 . GLU B 1 284 ? 208.946 232.754 243.743 1.00 68.45  ? 284 GLU B OE2 1 
ATOM   8382  N  N   . ILE B 1 285 ? 209.278 227.565 242.366 1.00 65.15  ? 285 ILE B N   1 
ATOM   8383  C  CA  . ILE B 1 285 ? 208.174 226.768 242.895 1.00 65.15  ? 285 ILE B CA  1 
ATOM   8384  C  C   . ILE B 1 285 ? 208.524 226.234 244.279 1.00 65.15  ? 285 ILE B C   1 
ATOM   8385  O  O   . ILE B 1 285 ? 207.726 226.323 245.223 1.00 65.15  ? 285 ILE B O   1 
ATOM   8386  C  CB  . ILE B 1 285 ? 207.819 225.630 241.924 1.00 65.15  ? 285 ILE B CB  1 
ATOM   8387  C  CG1 . ILE B 1 285 ? 207.044 226.177 240.727 1.00 65.15  ? 285 ILE B CG1 1 
ATOM   8388  C  CG2 . ILE B 1 285 ? 207.009 224.570 242.631 1.00 65.15  ? 285 ILE B CG2 1 
ATOM   8389  C  CD1 . ILE B 1 285 ? 207.126 225.302 239.497 1.00 65.15  ? 285 ILE B CD1 1 
ATOM   8390  N  N   . ILE B 1 286 ? 209.732 225.683 244.422 1.00 61.07  ? 286 ILE B N   1 
ATOM   8391  C  CA  . ILE B 1 286 ? 210.165 225.167 245.720 1.00 61.07  ? 286 ILE B CA  1 
ATOM   8392  C  C   . ILE B 1 286 ? 210.194 226.289 246.750 1.00 61.07  ? 286 ILE B C   1 
ATOM   8393  O  O   . ILE B 1 286 ? 209.705 226.136 247.879 1.00 61.07  ? 286 ILE B O   1 
ATOM   8394  C  CB  . ILE B 1 286 ? 211.534 224.478 245.601 1.00 61.07  ? 286 ILE B CB  1 
ATOM   8395  C  CG1 . ILE B 1 286 ? 211.405 223.160 244.851 1.00 61.07  ? 286 ILE B CG1 1 
ATOM   8396  C  CG2 . ILE B 1 286 ? 212.117 224.224 246.966 1.00 61.07  ? 286 ILE B CG2 1 
ATOM   8397  C  CD1 . ILE B 1 286 ? 212.699 222.397 244.757 1.00 61.07  ? 286 ILE B CD1 1 
ATOM   8398  N  N   . CYS B 1 287 ? 210.757 227.442 246.371 1.00 66.33  ? 287 CYS B N   1 
ATOM   8399  C  CA  . CYS B 1 287 ? 210.834 228.567 247.299 1.00 66.33  ? 287 CYS B CA  1 
ATOM   8400  C  C   . CYS B 1 287 ? 209.448 229.024 247.731 1.00 66.33  ? 287 CYS B C   1 
ATOM   8401  O  O   . CYS B 1 287 ? 209.191 229.230 248.924 1.00 66.33  ? 287 CYS B O   1 
ATOM   8402  C  CB  . CYS B 1 287 ? 211.596 229.725 246.658 1.00 66.33  ? 287 CYS B CB  1 
ATOM   8403  S  SG  . CYS B 1 287 ? 213.375 229.495 246.548 1.00 66.33  ? 287 CYS B SG  1 
ATOM   8404  N  N   . ARG B 1 288 ? 208.531 229.169 246.774 1.00 65.31  ? 288 ARG B N   1 
ATOM   8405  C  CA  . ARG B 1 288 ? 207.217 229.701 247.101 1.00 65.31  ? 288 ARG B CA  1 
ATOM   8406  C  C   . ARG B 1 288 ? 206.425 228.718 247.945 1.00 65.31  ? 288 ARG B C   1 
ATOM   8407  O  O   . ARG B 1 288 ? 205.652 229.125 248.817 1.00 65.31  ? 288 ARG B O   1 
ATOM   8408  C  CB  . ARG B 1 288 ? 206.457 230.069 245.825 1.00 65.31  ? 288 ARG B CB  1 
ATOM   8409  C  CG  . ARG B 1 288 ? 205.920 228.894 245.028 1.00 65.31  ? 288 ARG B CG  1 
ATOM   8410  C  CD  . ARG B 1 288 ? 205.045 229.361 243.876 1.00 65.31  ? 288 ARG B CD  1 
ATOM   8411  N  NE  . ARG B 1 288 ? 205.820 229.989 242.814 1.00 65.31  ? 288 ARG B NE  1 
ATOM   8412  C  CZ  . ARG B 1 288 ? 205.290 230.590 241.757 1.00 65.31  ? 288 ARG B CZ  1 
ATOM   8413  N  NH1 . ARG B 1 288 ? 203.980 230.665 241.590 1.00 65.31  ? 288 ARG B NH1 1 
ATOM   8414  N  NH2 . ARG B 1 288 ? 206.094 231.129 240.845 1.00 65.31  ? 288 ARG B NH2 1 
ATOM   8415  N  N   . ASN B 1 289 ? 206.625 227.415 247.733 1.00 62.21  ? 289 ASN B N   1 
ATOM   8416  C  CA  . ASN B 1 289 ? 205.900 226.442 248.542 1.00 62.21  ? 289 ASN B CA  1 
ATOM   8417  C  C   . ASN B 1 289 ? 206.448 226.376 249.964 1.00 62.21  ? 289 ASN B C   1 
ATOM   8418  O  O   . ASN B 1 289 ? 205.678 226.281 250.929 1.00 62.21  ? 289 ASN B O   1 
ATOM   8419  C  CB  . ASN B 1 289 ? 205.945 225.075 247.873 1.00 62.21  ? 289 ASN B CB  1 
ATOM   8420  C  CG  . ASN B 1 289 ? 204.892 224.930 246.811 1.00 62.21  ? 289 ASN B CG  1 
ATOM   8421  O  OD1 . ASN B 1 289 ? 203.699 225.031 247.090 1.00 62.21  ? 289 ASN B OD1 1 
ATOM   8422  N  ND2 . ASN B 1 289 ? 205.323 224.700 245.582 1.00 62.21  ? 289 ASN B ND2 1 
ATOM   8423  N  N   . ILE B 1 290 ? 207.773 226.420 250.116 1.00 61.10  ? 290 ILE B N   1 
ATOM   8424  C  CA  . ILE B 1 290 ? 208.341 226.480 251.457 1.00 61.10  ? 290 ILE B CA  1 
ATOM   8425  C  C   . ILE B 1 290 ? 207.830 227.714 252.183 1.00 61.10  ? 290 ILE B C   1 
ATOM   8426  O  O   . ILE B 1 290 ? 207.493 227.660 253.370 1.00 61.10  ? 290 ILE B O   1 
ATOM   8427  C  CB  . ILE B 1 290 ? 209.876 226.457 251.393 1.00 61.10  ? 290 ILE B CB  1 
ATOM   8428  C  CG1 . ILE B 1 290 ? 210.372 225.109 250.879 1.00 61.10  ? 290 ILE B CG1 1 
ATOM   8429  C  CG2 . ILE B 1 290 ? 210.463 226.736 252.755 1.00 61.10  ? 290 ILE B CG2 1 
ATOM   8430  C  CD1 . ILE B 1 290 ? 211.827 225.113 250.526 1.00 61.10  ? 290 ILE B CD1 1 
ATOM   8431  N  N   . GLU B 1 291 ? 207.750 228.846 251.478 1.00 68.67  ? 291 GLU B N   1 
ATOM   8432  C  CA  . GLU B 1 291 ? 207.218 230.059 252.093 1.00 68.67  ? 291 GLU B CA  1 
ATOM   8433  C  C   . GLU B 1 291 ? 205.750 229.894 252.468 1.00 68.67  ? 291 GLU B C   1 
ATOM   8434  O  O   . GLU B 1 291 ? 205.317 230.345 253.536 1.00 68.67  ? 291 GLU B O   1 
ATOM   8435  C  CB  . GLU B 1 291 ? 207.397 231.244 251.146 1.00 68.67  ? 291 GLU B CB  1 
ATOM   8436  C  CG  . GLU B 1 291 ? 206.797 232.542 251.654 1.00 68.67  ? 291 GLU B CG  1 
ATOM   8437  C  CD  . GLU B 1 291 ? 207.434 233.762 251.020 1.00 68.67  ? 291 GLU B CD  1 
ATOM   8438  O  OE1 . GLU B 1 291 ? 208.340 233.590 250.178 1.00 68.67  ? 291 GLU B OE1 1 
ATOM   8439  O  OE2 . GLU B 1 291 ? 207.027 234.893 251.361 1.00 68.67  ? 291 GLU B OE2 1 
ATOM   8440  N  N   . SER B 1 292 ? 204.965 229.260 251.596 1.00 64.99  ? 292 SER B N   1 
ATOM   8441  C  CA  . SER B 1 292 ? 203.548 229.082 251.876 1.00 64.99  ? 292 SER B CA  1 
ATOM   8442  C  C   . SER B 1 292 ? 203.336 228.234 253.114 1.00 64.99  ? 292 SER B C   1 
ATOM   8443  O  O   . SER B 1 292 ? 202.419 228.497 253.899 1.00 64.99  ? 292 SER B O   1 
ATOM   8444  C  CB  . SER B 1 292 ? 202.850 228.446 250.678 1.00 64.99  ? 292 SER B CB  1 
ATOM   8445  O  OG  . SER B 1 292 ? 203.272 227.105 250.506 1.00 64.99  ? 292 SER B OG  1 
ATOM   8446  N  N   . VAL B 1 293 ? 204.158 227.205 253.297 1.00 65.98  ? 293 VAL B N   1 
ATOM   8447  C  CA  . VAL B 1 293 ? 204.090 226.430 254.531 1.00 65.98  ? 293 VAL B CA  1 
ATOM   8448  C  C   . VAL B 1 293 ? 204.548 227.269 255.720 1.00 65.98  ? 293 VAL B C   1 
ATOM   8449  O  O   . VAL B 1 293 ? 203.894 227.284 256.768 1.00 65.98  ? 293 VAL B O   1 
ATOM   8450  C  CB  . VAL B 1 293 ? 204.912 225.138 254.395 1.00 65.98  ? 293 VAL B CB  1 
ATOM   8451  C  CG1 . VAL B 1 293 ? 204.971 224.408 255.725 1.00 65.98  ? 293 VAL B CG1 1 
ATOM   8452  C  CG2 . VAL B 1 293 ? 204.315 224.244 253.319 1.00 65.98  ? 293 VAL B CG2 1 
ATOM   8453  N  N   . LEU B 1 294 ? 205.656 227.993 255.578 1.00 69.50  ? 294 LEU B N   1 
ATOM   8454  C  CA  . LEU B 1 294 ? 206.210 228.822 256.646 1.00 69.50  ? 294 LEU B CA  1 
ATOM   8455  C  C   . LEU B 1 294 ? 206.180 230.276 256.184 1.00 69.50  ? 294 LEU B C   1 
ATOM   8456  O  O   . LEU B 1 294 ? 207.155 230.800 255.645 1.00 69.50  ? 294 LEU B O   1 
ATOM   8457  C  CB  . LEU B 1 294 ? 207.624 228.397 256.985 1.00 69.50  ? 294 LEU B CB  1 
ATOM   8458  C  CG  . LEU B 1 294 ? 207.890 226.924 257.230 1.00 69.50  ? 294 LEU B CG  1 
ATOM   8459  C  CD1 . LEU B 1 294 ? 209.370 226.665 257.072 1.00 69.50  ? 294 LEU B CD1 1 
ATOM   8460  C  CD2 . LEU B 1 294 ? 207.418 226.538 258.613 1.00 69.50  ? 294 LEU B CD2 1 
ATOM   8461  N  N   . ASN B 1 295 ? 205.036 230.925 256.391 1.00 72.88  ? 295 ASN B N   1 
ATOM   8462  C  CA  . ASN B 1 295 ? 204.884 232.356 256.158 1.00 72.88  ? 295 ASN B CA  1 
ATOM   8463  C  C   . ASN B 1 295 ? 205.932 233.165 256.911 1.00 72.88  ? 295 ASN B C   1 
ATOM   8464  O  O   . ASN B 1 295 ? 206.478 232.701 257.917 1.00 72.88  ? 295 ASN B O   1 
ATOM   8465  C  CB  . ASN B 1 295 ? 203.491 232.815 256.581 1.00 72.88  ? 295 ASN B CB  1 
ATOM   8466  C  CG  . ASN B 1 295 ? 203.264 232.671 258.071 1.00 72.88  ? 295 ASN B CG  1 
ATOM   8467  O  OD1 . ASN B 1 295 ? 202.949 231.587 258.560 1.00 72.88  ? 295 ASN B OD1 1 
ATOM   8468  N  ND2 . ASN B 1 295 ? 203.433 233.764 258.803 1.00 72.88  ? 295 ASN B ND2 1 
ATOM   8469  N  N   . GLU B 1 296 ? 206.206 234.378 256.431 1.00 73.45  ? 296 GLU B N   1 
ATOM   8470  C  CA  . GLU B 1 296 ? 207.151 235.296 257.063 1.00 73.45  ? 296 GLU B CA  1 
ATOM   8471  C  C   . GLU B 1 296 ? 208.540 234.667 257.166 1.00 73.45  ? 296 GLU B C   1 
ATOM   8472  O  O   . GLU B 1 296 ? 209.062 234.412 258.251 1.00 73.45  ? 296 GLU B O   1 
ATOM   8473  C  CB  . GLU B 1 296 ? 206.644 235.747 258.438 1.00 73.45  ? 296 GLU B CB  1 
ATOM   8474  C  CG  . GLU B 1 296 ? 205.440 236.673 258.384 1.00 73.45  ? 296 GLU B CG  1 
ATOM   8475  C  CD  . GLU B 1 296 ? 205.776 238.035 257.810 1.00 73.45  ? 296 GLU B CD  1 
ATOM   8476  O  OE1 . GLU B 1 296 ? 206.932 238.481 257.971 1.00 73.45  ? 296 GLU B OE1 1 
ATOM   8477  O  OE2 . GLU B 1 296 ? 204.885 238.660 257.198 1.00 73.45  ? 296 GLU B OE2 1 
ATOM   8478  N  N   . SER B 1 297 ? 209.130 234.411 256.003 1.00 71.49  ? 297 SER B N   1 
ATOM   8479  C  CA  . SER B 1 297 ? 210.458 233.822 255.955 1.00 71.49  ? 297 SER B CA  1 
ATOM   8480  C  C   . SER B 1 297 ? 211.107 234.177 254.629 1.00 71.49  ? 297 SER B C   1 
ATOM   8481  O  O   . SER B 1 297 ? 210.434 234.557 253.670 1.00 71.49  ? 297 SER B O   1 
ATOM   8482  C  CB  . SER B 1 297 ? 210.402 232.304 256.137 1.00 71.49  ? 297 SER B CB  1 
ATOM   8483  O  OG  . SER B 1 297 ? 211.685 231.777 256.420 1.00 71.49  ? 297 SER B OG  1 
ATOM   8484  N  N   . HIS B 1 298 ? 212.429 234.045 254.592 1.00 71.75  ? 298 HIS B N   1 
ATOM   8485  C  CA  . HIS B 1 298 ? 213.212 234.260 253.385 1.00 71.75  ? 298 HIS B CA  1 
ATOM   8486  C  C   . HIS B 1 298 ? 214.020 233.005 253.098 1.00 71.75  ? 298 HIS B C   1 
ATOM   8487  O  O   . HIS B 1 298 ? 214.831 232.581 253.925 1.00 71.75  ? 298 HIS B O   1 
ATOM   8488  C  CB  . HIS B 1 298 ? 214.138 235.467 253.533 1.00 71.75  ? 298 HIS B CB  1 
ATOM   8489  C  CG  . HIS B 1 298 ? 214.967 235.747 252.319 1.00 71.75  ? 298 HIS B CG  1 
ATOM   8490  N  ND1 . HIS B 1 298 ? 216.170 235.118 252.079 1.00 71.75  ? 298 HIS B ND1 1 
ATOM   8491  C  CD2 . HIS B 1 298 ? 214.770 236.591 251.279 1.00 71.75  ? 298 HIS B CD2 1 
ATOM   8492  C  CE1 . HIS B 1 298 ? 216.676 235.560 250.942 1.00 71.75  ? 298 HIS B CE1 1 
ATOM   8493  N  NE2 . HIS B 1 298 ? 215.846 236.455 250.436 1.00 71.75  ? 298 HIS B NE2 1 
ATOM   8494  N  N   . VAL B 1 299 ? 213.804 232.417 251.928 1.00 63.59  ? 299 VAL B N   1 
ATOM   8495  C  CA  . VAL B 1 299 ? 214.443 231.167 251.558 1.00 63.59  ? 299 VAL B CA  1 
ATOM   8496  C  C   . VAL B 1 299 ? 215.304 231.418 250.329 1.00 63.59  ? 299 VAL B C   1 
ATOM   8497  O  O   . VAL B 1 299 ? 215.090 232.369 249.579 1.00 63.59  ? 299 VAL B O   1 
ATOM   8498  C  CB  . VAL B 1 299 ? 213.417 230.051 251.294 1.00 63.59  ? 299 VAL B CB  1 
ATOM   8499  C  CG1 . VAL B 1 299 ? 212.536 229.851 252.510 1.00 63.59  ? 299 VAL B CG1 1 
ATOM   8500  C  CG2 . VAL B 1 299 ? 212.566 230.397 250.092 1.00 63.59  ? 299 VAL B CG2 1 
ATOM   8501  N  N   . SER B 1 300 ? 216.295 230.555 250.130 1.00 55.69  ? 300 SER B N   1 
ATOM   8502  C  CA  . SER B 1 300 ? 217.108 230.701 248.934 1.00 55.69  ? 300 SER B CA  1 
ATOM   8503  C  C   . SER B 1 300 ? 217.788 229.384 248.608 1.00 55.69  ? 300 SER B C   1 
ATOM   8504  O  O   . SER B 1 300 ? 217.995 228.538 249.485 1.00 55.69  ? 300 SER B O   1 
ATOM   8505  C  CB  . SER B 1 300 ? 218.155 231.807 249.093 1.00 55.69  ? 300 SER B CB  1 
ATOM   8506  O  OG  . SER B 1 300 ? 219.285 231.336 249.799 1.00 55.69  ? 300 SER B OG  1 
ATOM   8507  N  N   . LEU B 1 301 ? 218.142 229.235 247.338 1.00 54.05  ? 301 LEU B N   1 
ATOM   8508  C  CA  . LEU B 1 301 ? 218.795 228.046 246.819 1.00 54.05  ? 301 LEU B CA  1 
ATOM   8509  C  C   . LEU B 1 301 ? 220.062 228.435 246.077 1.00 54.05  ? 301 LEU B C   1 
ATOM   8510  O  O   . LEU B 1 301 ? 220.091 229.435 245.351 1.00 54.05  ? 301 LEU B O   1 
ATOM   8511  C  CB  . LEU B 1 301 ? 217.874 227.272 245.876 1.00 54.05  ? 301 LEU B CB  1 
ATOM   8512  C  CG  . LEU B 1 301 ? 216.891 226.266 246.469 1.00 54.05  ? 301 LEU B CG  1 
ATOM   8513  C  CD1 . LEU B 1 301 ? 215.672 226.960 247.006 1.00 54.05  ? 301 LEU B CD1 1 
ATOM   8514  C  CD2 . LEU B 1 301 ? 216.496 225.240 245.429 1.00 54.05  ? 301 LEU B CD2 1 
ATOM   8515  N  N   . PHE B 1 302 ? 221.104 227.637 246.253 1.00 58.17  ? 302 PHE B N   1 
ATOM   8516  C  CA  . PHE B 1 302 ? 222.319 227.744 245.468 1.00 58.17  ? 302 PHE B CA  1 
ATOM   8517  C  C   . PHE B 1 302 ? 222.660 226.367 244.929 1.00 58.17  ? 302 PHE B C   1 
ATOM   8518  O  O   . PHE B 1 302 ? 222.420 225.354 245.588 1.00 58.17  ? 302 PHE B O   1 
ATOM   8519  C  CB  . PHE B 1 302 ? 223.496 228.277 246.296 1.00 58.17  ? 302 PHE B CB  1 
ATOM   8520  C  CG  . PHE B 1 302 ? 223.319 229.687 246.778 1.00 58.17  ? 302 PHE B CG  1 
ATOM   8521  C  CD1 . PHE B 1 302 ? 222.623 229.953 247.945 1.00 58.17  ? 302 PHE B CD1 1 
ATOM   8522  C  CD2 . PHE B 1 302 ? 223.864 230.746 246.073 1.00 58.17  ? 302 PHE B CD2 1 
ATOM   8523  C  CE1 . PHE B 1 302 ? 222.463 231.250 248.393 1.00 58.17  ? 302 PHE B CE1 1 
ATOM   8524  C  CE2 . PHE B 1 302 ? 223.708 232.046 246.516 1.00 58.17  ? 302 PHE B CE2 1 
ATOM   8525  C  CZ  . PHE B 1 302 ? 223.007 232.298 247.678 1.00 58.17  ? 302 PHE B CZ  1 
ATOM   8526  N  N   . ALA B 1 303 ? 223.227 226.334 243.733 1.00 63.91  ? 303 ALA B N   1 
ATOM   8527  C  CA  . ALA B 1 303 ? 223.639 225.088 243.103 1.00 63.91  ? 303 ALA B CA  1 
ATOM   8528  C  C   . ALA B 1 303 ? 225.146 225.095 242.906 1.00 63.91  ? 303 ALA B C   1 
ATOM   8529  O  O   . ALA B 1 303 ? 225.723 226.121 242.535 1.00 63.91  ? 303 ALA B O   1 
ATOM   8530  C  CB  . ALA B 1 303 ? 222.932 224.884 241.764 1.00 63.91  ? 303 ALA B CB  1 
ATOM   8531  N  N   . LEU B 1 304 ? 225.787 223.954 243.159 1.00 68.60  ? 304 LEU B N   1 
ATOM   8532  C  CA  . LEU B 1 304 ? 227.242 223.868 243.115 1.00 68.60  ? 304 LEU B CA  1 
ATOM   8533  C  C   . LEU B 1 304 ? 227.679 223.509 241.703 1.00 68.60  ? 304 LEU B C   1 
ATOM   8534  O  O   . LEU B 1 304 ? 227.675 222.333 241.325 1.00 68.60  ? 304 LEU B O   1 
ATOM   8535  C  CB  . LEU B 1 304 ? 227.748 222.838 244.120 1.00 68.60  ? 304 LEU B CB  1 
ATOM   8536  C  CG  . LEU B 1 304 ? 228.122 223.337 245.520 1.00 68.60  ? 304 LEU B CG  1 
ATOM   8537  C  CD1 . LEU B 1 304 ? 229.252 224.354 245.449 1.00 68.60  ? 304 LEU B CD1 1 
ATOM   8538  C  CD2 . LEU B 1 304 ? 226.916 223.919 246.244 1.00 68.60  ? 304 LEU B CD2 1 
ATOM   8539  N  N   . ARG B 1 305 ? 228.064 224.518 240.925 1.00 74.20  ? 305 ARG B N   1 
ATOM   8540  C  CA  . ARG B 1 305 ? 228.609 224.326 239.588 1.00 74.20  ? 305 ARG B CA  1 
ATOM   8541  C  C   . ARG B 1 305 ? 230.118 224.502 239.666 1.00 74.20  ? 305 ARG B C   1 
ATOM   8542  O  O   . ARG B 1 305 ? 230.599 225.556 240.095 1.00 74.20  ? 305 ARG B O   1 
ATOM   8543  C  CB  . ARG B 1 305 ? 227.996 225.316 238.595 1.00 74.20  ? 305 ARG B CB  1 
ATOM   8544  C  CG  . ARG B 1 305 ? 226.530 225.061 238.293 1.00 74.20  ? 305 ARG B CG  1 
ATOM   8545  C  CD  . ARG B 1 305 ? 226.352 223.780 237.496 1.00 74.20  ? 305 ARG B CD  1 
ATOM   8546  N  NE  . ARG B 1 305 ? 224.946 223.453 237.292 1.00 74.20  ? 305 ARG B NE  1 
ATOM   8547  C  CZ  . ARG B 1 305 ? 224.249 222.632 238.066 1.00 74.20  ? 305 ARG B CZ  1 
ATOM   8548  N  NH1 . ARG B 1 305 ? 224.799 222.033 239.110 1.00 74.20  ? 305 ARG B NH1 1 
ATOM   8549  N  NH2 . ARG B 1 305 ? 222.969 222.407 237.786 1.00 74.20  ? 305 ARG B NH2 1 
ATOM   8550  N  N   . ASN B 1 306 ? 230.855 223.465 239.268 1.00 75.12  ? 306 ASN B N   1 
ATOM   8551  C  CA  . ASN B 1 306 ? 232.316 223.470 239.330 1.00 75.12  ? 306 ASN B CA  1 
ATOM   8552  C  C   . ASN B 1 306 ? 232.803 223.793 240.740 1.00 75.12  ? 306 ASN B C   1 
ATOM   8553  O  O   . ASN B 1 306 ? 233.784 224.513 240.935 1.00 75.12  ? 306 ASN B O   1 
ATOM   8554  C  CB  . ASN B 1 306 ? 232.906 224.443 238.308 1.00 75.12  ? 306 ASN B CB  1 
ATOM   8555  C  CG  . ASN B 1 306 ? 232.368 224.216 236.909 1.00 75.12  ? 306 ASN B CG  1 
ATOM   8556  O  OD1 . ASN B 1 306 ? 232.047 223.089 236.530 1.00 75.12  ? 306 ASN B OD1 1 
ATOM   8557  N  ND2 . ASN B 1 306 ? 232.267 225.288 236.132 1.00 75.12  ? 306 ASN B ND2 1 
ATOM   8558  N  N   . GLY B 1 307 ? 232.096 223.265 241.736 1.00 71.37  ? 307 GLY B N   1 
ATOM   8559  C  CA  . GLY B 1 307 ? 232.458 223.495 243.119 1.00 71.37  ? 307 GLY B CA  1 
ATOM   8560  C  C   . GLY B 1 307 ? 232.126 224.868 243.650 1.00 71.37  ? 307 GLY B C   1 
ATOM   8561  O  O   . GLY B 1 307 ? 232.523 225.195 244.772 1.00 71.37  ? 307 GLY B O   1 
ATOM   8562  N  N   . MET B 1 308 ? 231.400 225.681 242.891 1.00 72.20  ? 308 MET B N   1 
ATOM   8563  C  CA  . MET B 1 308 ? 231.105 227.041 243.288 1.00 72.20  ? 308 MET B CA  1 
ATOM   8564  C  C   . MET B 1 308 ? 229.599 227.253 243.332 1.00 72.20  ? 308 MET B C   1 
ATOM   8565  O  O   . MET B 1 308 ? 228.896 226.869 242.388 1.00 72.20  ? 308 MET B O   1 
ATOM   8566  C  CB  . MET B 1 308 ? 231.746 228.044 242.315 1.00 72.20  ? 308 MET B CB  1 
ATOM   8567  C  CG  . MET B 1 308 ? 231.674 229.492 242.770 1.00 72.20  ? 308 MET B CG  1 
ATOM   8568  S  SD  . MET B 1 308 ? 232.703 229.822 244.213 1.00 72.20  ? 308 MET B SD  1 
ATOM   8569  C  CE  . MET B 1 308 ? 231.888 231.268 244.885 1.00 72.20  ? 308 MET B CE  1 
ATOM   8570  N  N   . PRO B 1 309 ? 229.067 227.830 244.402 1.00 68.02  ? 309 PRO B N   1 
ATOM   8571  C  CA  . PRO B 1 309 ? 227.630 228.108 244.446 1.00 68.02  ? 309 PRO B CA  1 
ATOM   8572  C  C   . PRO B 1 309 ? 227.221 229.158 243.427 1.00 68.02  ? 309 PRO B C   1 
ATOM   8573  O  O   . PRO B 1 309 ? 227.960 230.101 243.134 1.00 68.02  ? 309 PRO B O   1 
ATOM   8574  C  CB  . PRO B 1 309 ? 227.411 228.612 245.877 1.00 68.02  ? 309 PRO B CB  1 
ATOM   8575  C  CG  . PRO B 1 309 ? 228.748 229.091 246.319 1.00 68.02  ? 309 PRO B CG  1 
ATOM   8576  C  CD  . PRO B 1 309 ? 229.742 228.194 245.655 1.00 68.02  ? 309 PRO B CD  1 
ATOM   8577  N  N   . ILE B 1 310 ? 226.022 228.976 242.880 1.00 62.54  ? 310 ILE B N   1 
ATOM   8578  C  CA  . ILE B 1 310 ? 225.371 229.967 242.032 1.00 62.54  ? 310 ILE B CA  1 
ATOM   8579  C  C   . ILE B 1 310 ? 223.932 230.116 242.501 1.00 62.54  ? 310 ILE B C   1 
ATOM   8580  O  O   . ILE B 1 310 ? 223.286 229.127 242.867 1.00 62.54  ? 310 ILE B O   1 
ATOM   8581  C  CB  . ILE B 1 310 ? 225.422 229.586 240.538 1.00 62.54  ? 310 ILE B CB  1 
ATOM   8582  C  CG1 . ILE B 1 310 ? 224.675 228.278 240.281 1.00 62.54  ? 310 ILE B CG1 1 
ATOM   8583  C  CG2 . ILE B 1 310 ? 226.863 229.480 240.061 1.00 62.54  ? 310 ILE B CG2 1 
ATOM   8584  C  CD1 . ILE B 1 310 ? 224.405 228.007 238.819 1.00 62.54  ? 310 ILE B CD1 1 
ATOM   8585  N  N   . HIS B 1 311 ? 223.441 231.353 242.511 1.00 62.75  ? 311 HIS B N   1 
ATOM   8586  C  CA  . HIS B 1 311 ? 222.083 231.618 242.963 1.00 62.75  ? 311 HIS B CA  1 
ATOM   8587  C  C   . HIS B 1 311 ? 221.067 230.977 242.027 1.00 62.75  ? 311 HIS B C   1 
ATOM   8588  O  O   . HIS B 1 311 ? 221.244 230.966 240.806 1.00 62.75  ? 311 HIS B O   1 
ATOM   8589  C  CB  . HIS B 1 311 ? 221.838 233.119 243.047 1.00 62.75  ? 311 HIS B CB  1 
ATOM   8590  C  CG  . HIS B 1 311 ? 220.521 233.479 243.653 1.00 62.75  ? 311 HIS B CG  1 
ATOM   8591  N  ND1 . HIS B 1 311 ? 219.339 233.423 242.947 1.00 62.75  ? 311 HIS B ND1 1 
ATOM   8592  C  CD2 . HIS B 1 311 ? 220.198 233.906 244.895 1.00 62.75  ? 311 HIS B CD2 1 
ATOM   8593  C  CE1 . HIS B 1 311 ? 218.344 233.796 243.731 1.00 62.75  ? 311 HIS B CE1 1 
ATOM   8594  N  NE2 . HIS B 1 311 ? 218.838 234.094 244.919 1.00 62.75  ? 311 HIS B NE2 1 
ATOM   8595  N  N   . TRP B 1 312 ? 219.992 230.439 242.605 1.00 60.48  ? 312 TRP B N   1 
ATOM   8596  C  CA  . TRP B 1 312 ? 218.999 229.715 241.825 1.00 60.48  ? 312 TRP B CA  1 
ATOM   8597  C  C   . TRP B 1 312 ? 217.635 230.379 241.953 1.00 60.48  ? 312 TRP B C   1 
ATOM   8598  O  O   . TRP B 1 312 ? 216.975 230.645 240.944 1.00 60.48  ? 312 TRP B O   1 
ATOM   8599  C  CB  . TRP B 1 312 ? 218.964 228.256 242.281 1.00 60.48  ? 312 TRP B CB  1 
ATOM   8600  C  CG  . TRP B 1 312 ? 217.970 227.345 241.604 1.00 60.48  ? 312 TRP B CG  1 
ATOM   8601  C  CD1 . TRP B 1 312 ? 217.041 227.675 240.661 1.00 60.48  ? 312 TRP B CD1 1 
ATOM   8602  C  CD2 . TRP B 1 312 ? 217.827 225.938 241.826 1.00 60.48  ? 312 TRP B CD2 1 
ATOM   8603  N  NE1 . TRP B 1 312 ? 216.323 226.565 240.294 1.00 60.48  ? 312 TRP B NE1 1 
ATOM   8604  C  CE2 . TRP B 1 312 ? 216.788 225.485 240.995 1.00 60.48  ? 312 TRP B CE2 1 
ATOM   8605  C  CE3 . TRP B 1 312 ? 218.479 225.018 242.651 1.00 60.48  ? 312 TRP B CE3 1 
ATOM   8606  C  CZ2 . TRP B 1 312 ? 216.389 224.156 240.964 1.00 60.48  ? 312 TRP B CZ2 1 
ATOM   8607  C  CZ3 . TRP B 1 312 ? 218.081 223.708 242.622 1.00 60.48  ? 312 TRP B CZ3 1 
ATOM   8608  C  CH2 . TRP B 1 312 ? 217.046 223.284 241.785 1.00 60.48  ? 312 TRP B CH2 1 
ATOM   8609  N  N   . ALA B 1 313 ? 217.209 230.668 243.176 1.00 59.67  ? 313 ALA B N   1 
ATOM   8610  C  CA  . ALA B 1 313 ? 215.903 231.277 243.391 1.00 59.67  ? 313 ALA B CA  1 
ATOM   8611  C  C   . ALA B 1 313 ? 215.902 231.937 244.759 1.00 59.67  ? 313 ALA B C   1 
ATOM   8612  O  O   . ALA B 1 313 ? 216.818 231.746 245.562 1.00 59.67  ? 313 ALA B O   1 
ATOM   8613  C  CB  . ALA B 1 313 ? 214.779 230.248 243.278 1.00 59.67  ? 313 ALA B CB  1 
ATOM   8614  N  N   . SER B 1 314 ? 214.863 232.724 245.011 1.00 66.42  ? 314 SER B N   1 
ATOM   8615  C  CA  . SER B 1 314 ? 214.717 233.408 246.285 1.00 66.42  ? 314 SER B CA  1 
ATOM   8616  C  C   . SER B 1 314 ? 213.273 233.848 246.429 1.00 66.42  ? 314 SER B C   1 
ATOM   8617  O  O   . SER B 1 314 ? 212.483 233.762 245.486 1.00 66.42  ? 314 SER B O   1 
ATOM   8618  C  CB  . SER B 1 314 ? 215.656 234.611 246.396 1.00 66.42  ? 314 SER B CB  1 
ATOM   8619  O  OG  . SER B 1 314 ? 215.407 235.338 247.587 1.00 66.42  ? 314 SER B OG  1 
ATOM   8620  N  N   . SER B 1 315 ? 212.937 234.310 247.627 1.00 79.48  ? 315 SER B N   1 
ATOM   8621  C  CA  . SER B 1 315 ? 211.605 234.837 247.869 1.00 79.48  ? 315 SER B CA  1 
ATOM   8622  C  C   . SER B 1 315 ? 211.499 236.257 247.328 1.00 79.48  ? 315 SER B C   1 
ATOM   8623  O  O   . SER B 1 315 ? 212.503 236.962 247.189 1.00 79.48  ? 315 SER B O   1 
ATOM   8624  C  CB  . SER B 1 315 ? 211.291 234.815 249.362 1.00 79.48  ? 315 SER B CB  1 
ATOM   8625  O  OG  . SER B 1 315 ? 212.095 235.748 250.060 1.00 79.48  ? 315 SER B OG  1 
ATOM   8626  N  N   . SER B 1 316 ? 210.271 236.672 247.010 1.00 94.08  ? 316 SER B N   1 
ATOM   8627  C  CA  . SER B 1 316 ? 210.059 238.018 246.487 1.00 94.08  ? 316 SER B CA  1 
ATOM   8628  C  C   . SER B 1 316 ? 210.439 239.077 247.514 1.00 94.08  ? 316 SER B C   1 
ATOM   8629  O  O   . SER B 1 316 ? 211.056 240.093 247.172 1.00 94.08  ? 316 SER B O   1 
ATOM   8630  C  CB  . SER B 1 316 ? 208.604 238.189 246.050 1.00 94.08  ? 316 SER B CB  1 
ATOM   8631  O  OG  . SER B 1 316 ? 207.720 238.017 247.144 1.00 94.08  ? 316 SER B OG  1 
ATOM   8632  N  N   . HIS B 1 317 ? 210.082 238.858 248.777 1.00 100.17 ? 317 HIS B N   1 
ATOM   8633  C  CA  . HIS B 1 317 ? 210.382 239.804 249.851 1.00 100.17 ? 317 HIS B CA  1 
ATOM   8634  C  C   . HIS B 1 317 ? 211.817 239.576 250.306 1.00 100.17 ? 317 HIS B C   1 
ATOM   8635  O  O   . HIS B 1 317 ? 212.102 238.715 251.140 1.00 100.17 ? 317 HIS B O   1 
ATOM   8636  C  CB  . HIS B 1 317 ? 209.395 239.642 251.000 1.00 100.17 ? 317 HIS B CB  1 
ATOM   8637  C  CG  . HIS B 1 317 ? 209.481 240.725 252.028 1.00 100.17 ? 317 HIS B CG  1 
ATOM   8638  N  ND1 . HIS B 1 317 ? 209.020 240.566 253.317 1.00 100.17 ? 317 HIS B ND1 1 
ATOM   8639  C  CD2 . HIS B 1 317 ? 209.971 241.985 251.957 1.00 100.17 ? 317 HIS B CD2 1 
ATOM   8640  C  CE1 . HIS B 1 317 ? 209.223 241.681 253.996 1.00 100.17 ? 317 HIS B CE1 1 
ATOM   8641  N  NE2 . HIS B 1 317 ? 209.798 242.558 253.194 1.00 100.17 ? 317 HIS B NE2 1 
ATOM   8642  N  N   . GLY B 1 318 ? 212.736 240.362 249.750 1.00 101.45 ? 318 GLY B N   1 
ATOM   8643  C  CA  . GLY B 1 318 ? 214.144 240.248 250.066 1.00 101.45 ? 318 GLY B CA  1 
ATOM   8644  C  C   . GLY B 1 318 ? 214.612 241.007 251.285 1.00 101.45 ? 318 GLY B C   1 
ATOM   8645  O  O   . GLY B 1 318 ? 215.811 241.008 251.575 1.00 101.45 ? 318 GLY B O   1 
ATOM   8646  N  N   . ALA B 1 319 ? 213.705 241.656 252.011 1.00 103.29 ? 319 ALA B N   1 
ATOM   8647  C  CA  . ALA B 1 319 ? 214.095 242.430 253.178 1.00 103.29 ? 319 ALA B CA  1 
ATOM   8648  C  C   . ALA B 1 319 ? 214.487 241.514 254.334 1.00 103.29 ? 319 ALA B C   1 
ATOM   8649  O  O   . ALA B 1 319 ? 214.106 240.341 254.395 1.00 103.29 ? 319 ALA B O   1 
ATOM   8650  C  CB  . ALA B 1 319 ? 212.963 243.362 253.608 1.00 103.29 ? 319 ALA B CB  1 
ATOM   8651  N  N   . GLU B 1 320 ? 215.262 242.071 255.261 1.00 104.62 ? 320 GLU B N   1 
ATOM   8652  C  CA  . GLU B 1 320 ? 215.730 241.314 256.411 1.00 104.62 ? 320 GLU B CA  1 
ATOM   8653  C  C   . GLU B 1 320 ? 214.585 241.037 257.382 1.00 104.62 ? 320 GLU B C   1 
ATOM   8654  O  O   . GLU B 1 320 ? 213.529 241.674 257.345 1.00 104.62 ? 320 GLU B O   1 
ATOM   8655  C  CB  . GLU B 1 320 ? 216.852 242.066 257.127 1.00 104.62 ? 320 GLU B CB  1 
ATOM   8656  C  CG  . GLU B 1 320 ? 218.108 242.254 256.292 1.00 104.62 ? 320 GLU B CG  1 
ATOM   8657  C  CD  . GLU B 1 320 ? 219.223 242.934 257.063 1.00 104.62 ? 320 GLU B CD  1 
ATOM   8658  O  OE1 . GLU B 1 320 ? 219.218 242.858 258.309 1.00 104.62 ? 320 GLU B OE1 1 
ATOM   8659  O  OE2 . GLU B 1 320 ? 220.105 243.544 256.422 1.00 104.62 ? 320 GLU B OE2 1 
ATOM   8660  N  N   . ILE B 1 321 ? 214.812 240.066 258.263 1.00 97.33  ? 321 ILE B N   1 
ATOM   8661  C  CA  . ILE B 1 321 ? 213.837 239.652 259.263 1.00 97.33  ? 321 ILE B CA  1 
ATOM   8662  C  C   . ILE B 1 321 ? 214.451 239.837 260.642 1.00 97.33  ? 321 ILE B C   1 
ATOM   8663  O  O   . ILE B 1 321 ? 215.577 239.396 260.895 1.00 97.33  ? 321 ILE B O   1 
ATOM   8664  C  CB  . ILE B 1 321 ? 213.392 238.190 259.052 1.00 97.33  ? 321 ILE B CB  1 
ATOM   8665  C  CG1 . ILE B 1 321 ? 212.783 238.014 257.660 1.00 97.33  ? 321 ILE B CG1 1 
ATOM   8666  C  CG2 . ILE B 1 321 ? 212.399 237.773 260.126 1.00 97.33  ? 321 ILE B CG2 1 
ATOM   8667  C  CD1 . ILE B 1 321 ? 212.620 236.569 257.245 1.00 97.33  ? 321 ILE B CD1 1 
ATOM   8668  N  N   . GLN B 1 322 ? 213.709 240.493 261.531 1.00 99.31  ? 322 GLN B N   1 
ATOM   8669  C  CA  . GLN B 1 322 ? 214.204 240.753 262.875 1.00 99.31  ? 322 GLN B CA  1 
ATOM   8670  C  C   . GLN B 1 322 ? 214.304 239.459 263.674 1.00 99.31  ? 322 GLN B C   1 
ATOM   8671  O  O   . GLN B 1 322 ? 213.396 238.624 263.650 1.00 99.31  ? 322 GLN B O   1 
ATOM   8672  C  CB  . GLN B 1 322 ? 213.286 241.743 263.593 1.00 99.31  ? 322 GLN B CB  1 
ATOM   8673  C  CG  . GLN B 1 322 ? 213.092 243.056 262.851 1.00 99.31  ? 322 GLN B CG  1 
ATOM   8674  C  CD  . GLN B 1 322 ? 212.103 243.975 263.542 1.00 99.31  ? 322 GLN B CD  1 
ATOM   8675  O  OE1 . GLN B 1 322 ? 211.459 243.593 264.518 1.00 99.31  ? 322 GLN B OE1 1 
ATOM   8676  N  NE2 . GLN B 1 322 ? 211.978 245.197 263.035 1.00 99.31  ? 322 GLN B NE2 1 
ATOM   8677  N  N   . ASN B 1 323 ? 215.421 239.303 264.389 1.00 97.05  ? 323 ASN B N   1 
ATOM   8678  C  CA  . ASN B 1 323 ? 215.664 238.138 265.243 1.00 97.05  ? 323 ASN B CA  1 
ATOM   8679  C  C   . ASN B 1 323 ? 215.544 236.835 264.455 1.00 97.05  ? 323 ASN B C   1 
ATOM   8680  O  O   . ASN B 1 323 ? 214.960 235.853 264.918 1.00 97.05  ? 323 ASN B O   1 
ATOM   8681  C  CB  . ASN B 1 323 ? 214.720 238.136 266.446 1.00 97.05  ? 323 ASN B CB  1 
ATOM   8682  C  CG  . ASN B 1 323 ? 214.750 239.444 267.212 1.00 97.05  ? 323 ASN B CG  1 
ATOM   8683  O  OD1 . ASN B 1 323 ? 215.777 240.118 267.271 1.00 97.05  ? 323 ASN B OD1 1 
ATOM   8684  N  ND2 . ASN B 1 323 ? 213.617 239.810 267.801 1.00 97.05  ? 323 ASN B ND2 1 
ATOM   8685  N  N   . ALA B 1 324 ? 216.108 236.825 263.252 1.00 92.12  ? 324 ALA B N   1 
ATOM   8686  C  CA  . ALA B 1 324 ? 215.972 235.685 262.360 1.00 92.12  ? 324 ALA B CA  1 
ATOM   8687  C  C   . ALA B 1 324 ? 216.911 234.551 262.757 1.00 92.12  ? 324 ALA B C   1 
ATOM   8688  O  O   . ALA B 1 324 ? 217.984 234.770 263.327 1.00 92.12  ? 324 ALA B O   1 
ATOM   8689  C  CB  . ALA B 1 324 ? 216.246 236.101 260.915 1.00 92.12  ? 324 ALA B CB  1 
ATOM   8690  N  N   . GLN B 1 325 ? 216.488 233.327 262.446 1.00 82.77  ? 325 GLN B N   1 
ATOM   8691  C  CA  . GLN B 1 325 ? 217.286 232.126 262.634 1.00 82.77  ? 325 GLN B CA  1 
ATOM   8692  C  C   . GLN B 1 325 ? 217.326 231.356 261.322 1.00 82.77  ? 325 GLN B C   1 
ATOM   8693  O  O   . GLN B 1 325 ? 216.363 231.370 260.548 1.00 82.77  ? 325 GLN B O   1 
ATOM   8694  C  CB  . GLN B 1 325 ? 216.719 231.243 263.751 1.00 82.77  ? 325 GLN B CB  1 
ATOM   8695  C  CG  . GLN B 1 325 ? 216.828 231.857 265.136 1.00 82.77  ? 325 GLN B CG  1 
ATOM   8696  C  CD  . GLN B 1 325 ? 216.333 230.928 266.227 1.00 82.77  ? 325 GLN B CD  1 
ATOM   8697  O  OE1 . GLN B 1 325 ? 215.870 229.821 265.953 1.00 82.77  ? 325 GLN B OE1 1 
ATOM   8698  N  NE2 . GLN B 1 325 ? 216.429 231.376 267.473 1.00 82.77  ? 325 GLN B NE2 1 
ATOM   8699  N  N   . SER B 1 326 ? 218.445 230.675 261.083 1.00 67.83  ? 326 SER B N   1 
ATOM   8700  C  CA  . SER B 1 326 ? 218.737 230.075 259.790 1.00 67.83  ? 326 SER B CA  1 
ATOM   8701  C  C   . SER B 1 326 ? 218.909 228.566 259.904 1.00 67.83  ? 326 SER B C   1 
ATOM   8702  O  O   . SER B 1 326 ? 219.606 228.072 260.795 1.00 67.83  ? 326 SER B O   1 
ATOM   8703  C  CB  . SER B 1 326 ? 219.999 230.689 259.178 1.00 67.83  ? 326 SER B CB  1 
ATOM   8704  O  OG  . SER B 1 326 ? 221.160 230.247 259.856 1.00 67.83  ? 326 SER B OG  1 
ATOM   8705  N  N   . TRP B 1 327 ? 218.271 227.851 258.983 1.00 57.16  ? 327 TRP B N   1 
ATOM   8706  C  CA  . TRP B 1 327 ? 218.429 226.415 258.798 1.00 57.16  ? 327 TRP B CA  1 
ATOM   8707  C  C   . TRP B 1 327 ? 219.088 226.198 257.447 1.00 57.16  ? 327 TRP B C   1 
ATOM   8708  O  O   . TRP B 1 327 ? 218.544 226.609 256.416 1.00 57.16  ? 327 TRP B O   1 
ATOM   8709  C  CB  . TRP B 1 327 ? 217.075 225.704 258.859 1.00 57.16  ? 327 TRP B CB  1 
ATOM   8710  C  CG  . TRP B 1 327 ? 217.104 224.357 259.501 1.00 57.16  ? 327 TRP B CG  1 
ATOM   8711  C  CD1 . TRP B 1 327 ? 217.171 223.154 258.871 1.00 57.16  ? 327 TRP B CD1 1 
ATOM   8712  C  CD2 . TRP B 1 327 ? 217.051 224.073 260.903 1.00 57.16  ? 327 TRP B CD2 1 
ATOM   8713  N  NE1 . TRP B 1 327 ? 217.168 222.136 259.791 1.00 57.16  ? 327 TRP B NE1 1 
ATOM   8714  C  CE2 . TRP B 1 327 ? 217.096 222.675 261.047 1.00 57.16  ? 327 TRP B CE2 1 
ATOM   8715  C  CE3 . TRP B 1 327 ? 216.973 224.868 262.050 1.00 57.16  ? 327 TRP B CE3 1 
ATOM   8716  C  CZ2 . TRP B 1 327 ? 217.065 222.054 262.290 1.00 57.16  ? 327 TRP B CZ2 1 
ATOM   8717  C  CZ3 . TRP B 1 327 ? 216.943 224.248 263.283 1.00 57.16  ? 327 TRP B CZ3 1 
ATOM   8718  C  CH2 . TRP B 1 327 ? 216.989 222.855 263.394 1.00 57.16  ? 327 TRP B CH2 1 
ATOM   8719  N  N   . SER B 1 328 ? 220.254 225.562 257.450 1.00 51.48  ? 328 SER B N   1 
ATOM   8720  C  CA  . SER B 1 328 ? 221.042 225.357 256.243 1.00 51.48  ? 328 SER B CA  1 
ATOM   8721  C  C   . SER B 1 328 ? 221.092 223.870 255.934 1.00 51.48  ? 328 SER B C   1 
ATOM   8722  O  O   . SER B 1 328 ? 221.617 223.087 256.731 1.00 51.48  ? 328 SER B O   1 
ATOM   8723  C  CB  . SER B 1 328 ? 222.451 225.921 256.418 1.00 51.48  ? 328 SER B CB  1 
ATOM   8724  O  OG  . SER B 1 328 ? 223.209 225.772 255.232 1.00 51.48  ? 328 SER B OG  1 
ATOM   8725  N  N   . ALA B 1 329 ? 220.560 223.486 254.779 1.00 47.88  ? 329 ALA B N   1 
ATOM   8726  C  CA  . ALA B 1 329 ? 220.488 222.090 254.387 1.00 47.88  ? 329 ALA B CA  1 
ATOM   8727  C  C   . ALA B 1 329 ? 221.282 221.881 253.111 1.00 47.88  ? 329 ALA B C   1 
ATOM   8728  O  O   . ALA B 1 329 ? 221.390 222.776 252.271 1.00 47.88  ? 329 ALA B O   1 
ATOM   8729  C  CB  . ALA B 1 329 ? 219.044 221.636 254.184 1.00 47.88  ? 329 ALA B CB  1 
ATOM   8730  N  N   . THR B 1 330 ? 221.845 220.689 252.980 1.00 51.10  ? 330 THR B N   1 
ATOM   8731  C  CA  . THR B 1 330 ? 222.729 220.349 251.875 1.00 51.10  ? 330 THR B CA  1 
ATOM   8732  C  C   . THR B 1 330 ? 222.003 219.406 250.923 1.00 51.10  ? 330 THR B C   1 
ATOM   8733  O  O   . THR B 1 330 ? 221.704 218.264 251.287 1.00 51.10  ? 330 THR B O   1 
ATOM   8734  C  CB  . THR B 1 330 ? 224.010 219.708 252.400 1.00 51.10  ? 330 THR B CB  1 
ATOM   8735  O  OG1 . THR B 1 330 ? 224.606 220.574 253.370 1.00 51.10  ? 330 THR B OG1 1 
ATOM   8736  C  CG2 . THR B 1 330 ? 224.989 219.489 251.276 1.00 51.10  ? 330 THR B CG2 1 
ATOM   8737  N  N   . ILE B 1 331 ? 221.733 219.878 249.710 1.00 51.88  ? 331 ILE B N   1 
ATOM   8738  C  CA  . ILE B 1 331 ? 221.011 219.104 248.708 1.00 51.88  ? 331 ILE B CA  1 
ATOM   8739  C  C   . ILE B 1 331 ? 221.989 218.149 248.046 1.00 51.88  ? 331 ILE B C   1 
ATOM   8740  O  O   . ILE B 1 331 ? 222.934 218.584 247.378 1.00 51.88  ? 331 ILE B O   1 
ATOM   8741  C  CB  . ILE B 1 331 ? 220.355 220.019 247.666 1.00 51.88  ? 331 ILE B CB  1 
ATOM   8742  C  CG1 . ILE B 1 331 ? 219.379 220.980 248.337 1.00 51.88  ? 331 ILE B CG1 1 
ATOM   8743  C  CG2 . ILE B 1 331 ? 219.654 219.197 246.610 1.00 51.88  ? 331 ILE B CG2 1 
ATOM   8744  C  CD1 . ILE B 1 331 ? 219.144 222.245 247.567 1.00 51.88  ? 331 ILE B CD1 1 
ATOM   8745  N  N   . ARG B 1 332 ? 221.751 216.853 248.217 1.00 57.97  ? 332 ARG B N   1 
ATOM   8746  C  CA  . ARG B 1 332 ? 222.635 215.809 247.729 1.00 57.97  ? 332 ARG B CA  1 
ATOM   8747  C  C   . ARG B 1 332 ? 221.842 214.850 246.856 1.00 57.97  ? 332 ARG B C   1 
ATOM   8748  O  O   . ARG B 1 332 ? 220.690 214.532 247.162 1.00 57.97  ? 332 ARG B O   1 
ATOM   8749  C  CB  . ARG B 1 332 ? 223.278 215.050 248.892 1.00 57.97  ? 332 ARG B CB  1 
ATOM   8750  C  CG  . ARG B 1 332 ? 223.950 215.937 249.933 1.00 57.97  ? 332 ARG B CG  1 
ATOM   8751  C  CD  . ARG B 1 332 ? 224.437 215.125 251.133 1.00 57.97  ? 332 ARG B CD  1 
ATOM   8752  N  NE  . ARG B 1 332 ? 225.515 214.213 250.773 1.00 57.97  ? 332 ARG B NE  1 
ATOM   8753  C  CZ  . ARG B 1 332 ? 225.356 212.919 250.529 1.00 57.97  ? 332 ARG B CZ  1 
ATOM   8754  N  NH1 . ARG B 1 332 ? 224.169 212.343 250.602 1.00 57.97  ? 332 ARG B NH1 1 
ATOM   8755  N  NH2 . ARG B 1 332 ? 226.414 212.188 250.196 1.00 57.97  ? 332 ARG B NH2 1 
ATOM   8756  N  N   . GLN B 1 333 ? 222.459 214.385 245.774 1.00 66.41  ? 333 GLN B N   1 
ATOM   8757  C  CA  . GLN B 1 333 ? 221.782 213.496 244.840 1.00 66.41  ? 333 GLN B CA  1 
ATOM   8758  C  C   . GLN B 1 333 ? 221.749 212.077 245.403 1.00 66.41  ? 333 GLN B C   1 
ATOM   8759  O  O   . GLN B 1 333 ? 222.075 211.833 246.568 1.00 66.41  ? 333 GLN B O   1 
ATOM   8760  C  CB  . GLN B 1 333 ? 222.447 213.547 243.468 1.00 66.41  ? 333 GLN B CB  1 
ATOM   8761  C  CG  . GLN B 1 333 ? 223.807 212.893 243.408 1.00 66.41  ? 333 GLN B CG  1 
ATOM   8762  C  CD  . GLN B 1 333 ? 224.887 213.789 243.949 1.00 66.41  ? 333 GLN B CD  1 
ATOM   8763  O  OE1 . GLN B 1 333 ? 224.712 215.004 244.032 1.00 66.41  ? 333 GLN B OE1 1 
ATOM   8764  N  NE2 . GLN B 1 333 ? 226.015 213.200 244.324 1.00 66.41  ? 333 GLN B NE2 1 
ATOM   8765  N  N   . ARG B 1 334 ? 221.339 211.118 244.569 1.00 73.51  ? 334 ARG B N   1 
ATOM   8766  C  CA  . ARG B 1 334 ? 221.151 209.746 245.026 1.00 73.51  ? 334 ARG B CA  1 
ATOM   8767  C  C   . ARG B 1 334 ? 222.442 209.105 245.509 1.00 73.51  ? 334 ARG B C   1 
ATOM   8768  O  O   . ARG B 1 334 ? 222.387 208.151 246.293 1.00 73.51  ? 334 ARG B O   1 
ATOM   8769  C  CB  . ARG B 1 334 ? 220.545 208.898 243.908 1.00 73.51  ? 334 ARG B CB  1 
ATOM   8770  C  CG  . ARG B 1 334 ? 221.448 208.724 242.703 1.00 73.51  ? 334 ARG B CG  1 
ATOM   8771  C  CD  . ARG B 1 334 ? 220.746 207.951 241.598 1.00 73.51  ? 334 ARG B CD  1 
ATOM   8772  N  NE  . ARG B 1 334 ? 221.596 207.779 240.426 1.00 73.51  ? 334 ARG B NE  1 
ATOM   8773  C  CZ  . ARG B 1 334 ? 221.232 207.135 239.325 1.00 73.51  ? 334 ARG B CZ  1 
ATOM   8774  N  NH1 . ARG B 1 334 ? 220.034 206.586 239.210 1.00 73.51  ? 334 ARG B NH1 1 
ATOM   8775  N  NH2 . ARG B 1 334 ? 222.092 207.039 238.315 1.00 73.51  ? 334 ARG B NH2 1 
ATOM   8776  N  N   . ASP B 1 335 ? 223.598 209.596 245.065 1.00 68.98  ? 335 ASP B N   1 
ATOM   8777  C  CA  . ASP B 1 335 ? 224.864 209.059 245.544 1.00 68.98  ? 335 ASP B CA  1 
ATOM   8778  C  C   . ASP B 1 335 ? 226.018 210.015 245.280 1.00 68.98  ? 335 ASP B C   1 
ATOM   8779  O  O   . ASP B 1 335 ? 226.289 210.370 244.129 1.00 68.98  ? 335 ASP B O   1 
ATOM   8780  C  CB  . ASP B 1 335 ? 225.152 207.706 244.894 1.00 68.98  ? 335 ASP B CB  1 
ATOM   8781  C  CG  . ASP B 1 335 ? 226.239 206.936 245.614 1.00 68.98  ? 335 ASP B CG  1 
ATOM   8782  O  OD1 . ASP B 1 335 ? 226.752 207.442 246.633 1.00 68.98  ? 335 ASP B OD1 1 
ATOM   8783  O  OD2 . ASP B 1 335 ? 226.581 205.823 245.160 1.00 68.98  ? 335 ASP B OD2 1 
ATOM   8784  N  N   . GLY B 1 336 ? 226.703 210.434 246.338 1.00 61.83  ? 336 GLY B N   1 
ATOM   8785  C  CA  . GLY B 1 336 ? 227.937 211.170 246.172 1.00 61.83  ? 336 GLY B CA  1 
ATOM   8786  C  C   . GLY B 1 336 ? 227.963 212.589 246.697 1.00 61.83  ? 336 GLY B C   1 
ATOM   8787  O  O   . GLY B 1 336 ? 227.360 212.909 247.725 1.00 61.83  ? 336 GLY B O   1 
ATOM   8788  N  N   . ALA B 1 337 ? 228.675 213.447 245.973 1.00 61.39  ? 337 ALA B N   1 
ATOM   8789  C  CA  . ALA B 1 337 ? 229.001 214.776 246.448 1.00 61.39  ? 337 ALA B CA  1 
ATOM   8790  C  C   . ALA B 1 337 ? 227.751 215.639 246.543 1.00 61.39  ? 337 ALA B C   1 
ATOM   8791  O  O   . ALA B 1 337 ? 226.747 215.370 245.883 1.00 61.39  ? 337 ALA B O   1 
ATOM   8792  C  CB  . ALA B 1 337 ? 230.020 215.428 245.515 1.00 61.39  ? 337 ALA B CB  1 
ATOM   8793  N  N   . PRO B 1 338 ? 227.779 216.670 247.384 1.00 57.52  ? 338 PRO B N   1 
ATOM   8794  C  CA  . PRO B 1 338 ? 226.644 217.594 247.442 1.00 57.52  ? 338 PRO B CA  1 
ATOM   8795  C  C   . PRO B 1 338 ? 226.438 218.280 246.104 1.00 57.52  ? 338 PRO B C   1 
ATOM   8796  O  O   . PRO B 1 338 ? 227.395 218.619 245.405 1.00 57.52  ? 338 PRO B O   1 
ATOM   8797  C  CB  . PRO B 1 338 ? 227.056 218.596 248.526 1.00 57.52  ? 338 PRO B CB  1 
ATOM   8798  C  CG  . PRO B 1 338 ? 228.111 217.905 249.315 1.00 57.52  ? 338 PRO B CG  1 
ATOM   8799  C  CD  . PRO B 1 338 ? 228.833 217.032 248.344 1.00 57.52  ? 338 PRO B CD  1 
ATOM   8800  N  N   . ALA B 1 339 ? 225.174 218.485 245.748 1.00 52.83  ? 339 ALA B N   1 
ATOM   8801  C  CA  . ALA B 1 339 ? 224.850 219.199 244.527 1.00 52.83  ? 339 ALA B CA  1 
ATOM   8802  C  C   . ALA B 1 339 ? 224.412 220.630 244.778 1.00 52.83  ? 339 ALA B C   1 
ATOM   8803  O  O   . ALA B 1 339 ? 224.478 221.452 243.858 1.00 52.83  ? 339 ALA B O   1 
ATOM   8804  C  CB  . ALA B 1 339 ? 223.753 218.463 243.751 1.00 52.83  ? 339 ALA B CB  1 
ATOM   8805  N  N   . GLY B 1 340 ? 223.986 220.958 245.989 1.00 52.26  ? 340 GLY B N   1 
ATOM   8806  C  CA  . GLY B 1 340 ? 223.566 222.326 246.222 1.00 52.26  ? 340 GLY B CA  1 
ATOM   8807  C  C   . GLY B 1 340 ? 223.397 222.608 247.694 1.00 52.26  ? 340 GLY B C   1 
ATOM   8808  O  O   . GLY B 1 340 ? 223.582 221.738 248.546 1.00 52.26  ? 340 GLY B O   1 
ATOM   8809  N  N   . ILE B 1 341 ? 223.023 223.850 247.980 1.00 49.63  ? 341 ILE B N   1 
ATOM   8810  C  CA  . ILE B 1 341 ? 222.799 224.316 249.339 1.00 49.63  ? 341 ILE B CA  1 
ATOM   8811  C  C   . ILE B 1 341 ? 221.486 225.082 249.377 1.00 49.63  ? 341 ILE B C   1 
ATOM   8812  O  O   . ILE B 1 341 ? 221.333 226.092 248.683 1.00 49.63  ? 341 ILE B O   1 
ATOM   8813  C  CB  . ILE B 1 341 ? 223.950 225.204 249.837 1.00 49.63  ? 341 ILE B CB  1 
ATOM   8814  C  CG1 . ILE B 1 341 ? 225.264 224.423 249.861 1.00 49.63  ? 341 ILE B CG1 1 
ATOM   8815  C  CG2 . ILE B 1 341 ? 223.635 225.758 251.215 1.00 49.63  ? 341 ILE B CG2 1 
ATOM   8816  C  CD1 . ILE B 1 341 ? 225.280 223.287 250.857 1.00 49.63  ? 341 ILE B CD1 1 
ATOM   8817  N  N   . LEU B 1 342 ? 220.547 224.611 250.182 1.00 48.09  ? 342 LEU B N   1 
ATOM   8818  C  CA  . LEU B 1 342 ? 219.342 225.353 250.502 1.00 48.09  ? 342 LEU B CA  1 
ATOM   8819  C  C   . LEU B 1 342 ? 219.544 226.060 251.832 1.00 48.09  ? 342 LEU B C   1 
ATOM   8820  O  O   . LEU B 1 342 ? 220.161 225.513 252.749 1.00 48.09  ? 342 LEU B O   1 
ATOM   8821  C  CB  . LEU B 1 342 ? 218.132 224.421 250.590 1.00 48.09  ? 342 LEU B CB  1 
ATOM   8822  C  CG  . LEU B 1 342 ? 216.913 224.950 251.352 1.00 48.09  ? 342 LEU B CG  1 
ATOM   8823  C  CD1 . LEU B 1 342 ? 216.238 226.076 250.603 1.00 48.09  ? 342 LEU B CD1 1 
ATOM   8824  C  CD2 . LEU B 1 342 ? 215.932 223.841 251.650 1.00 48.09  ? 342 LEU B CD2 1 
ATOM   8825  N  N   . GLN B 1 343 ? 219.038 227.283 251.943 1.00 55.21  ? 343 GLN B N   1 
ATOM   8826  C  CA  . GLN B 1 343 ? 219.020 227.918 253.249 1.00 55.21  ? 343 GLN B CA  1 
ATOM   8827  C  C   . GLN B 1 343 ? 217.684 228.607 253.466 1.00 55.21  ? 343 GLN B C   1 
ATOM   8828  O  O   . GLN B 1 343 ? 217.063 229.113 252.529 1.00 55.21  ? 343 GLN B O   1 
ATOM   8829  C  CB  . GLN B 1 343 ? 220.181 228.904 253.432 1.00 55.21  ? 343 GLN B CB  1 
ATOM   8830  C  CG  . GLN B 1 343 ? 220.175 230.101 252.519 1.00 55.21  ? 343 GLN B CG  1 
ATOM   8831  C  CD  . GLN B 1 343 ? 221.012 231.241 253.068 1.00 55.21  ? 343 GLN B CD  1 
ATOM   8832  O  OE1 . GLN B 1 343 ? 221.091 231.439 254.280 1.00 55.21  ? 343 GLN B OE1 1 
ATOM   8833  N  NE2 . GLN B 1 343 ? 221.640 231.997 252.177 1.00 55.21  ? 343 GLN B NE2 1 
ATOM   8834  N  N   . ILE B 1 344 ? 217.237 228.593 254.717 1.00 59.75  ? 344 ILE B N   1 
ATOM   8835  C  CA  . ILE B 1 344 ? 215.969 229.181 255.119 1.00 59.75  ? 344 ILE B CA  1 
ATOM   8836  C  C   . ILE B 1 344 ? 216.223 230.054 256.336 1.00 59.75  ? 344 ILE B C   1 
ATOM   8837  O  O   . ILE B 1 344 ? 216.970 229.676 257.240 1.00 59.75  ? 344 ILE B O   1 
ATOM   8838  C  CB  . ILE B 1 344 ? 214.914 228.098 255.439 1.00 59.75  ? 344 ILE B CB  1 
ATOM   8839  C  CG1 . ILE B 1 344 ? 214.679 227.201 254.226 1.00 59.75  ? 344 ILE B CG1 1 
ATOM   8840  C  CG2 . ILE B 1 344 ? 213.610 228.726 255.891 1.00 59.75  ? 344 ILE B CG2 1 
ATOM   8841  C  CD1 . ILE B 1 344 ? 213.612 226.159 254.442 1.00 59.75  ? 344 ILE B CD1 1 
ATOM   8842  N  N   . LYS B 1 345 ? 215.615 231.236 256.358 1.00 71.04  ? 345 LYS B N   1 
ATOM   8843  C  CA  . LYS B 1 345 ? 215.692 232.073 257.543 1.00 71.04  ? 345 LYS B CA  1 
ATOM   8844  C  C   . LYS B 1 345 ? 214.285 232.504 257.920 1.00 71.04  ? 345 LYS B C   1 
ATOM   8845  O  O   . LYS B 1 345 ? 213.486 232.875 257.055 1.00 71.04  ? 345 LYS B O   1 
ATOM   8846  C  CB  . LYS B 1 345 ? 216.599 233.291 257.329 1.00 71.04  ? 345 LYS B CB  1 
ATOM   8847  C  CG  . LYS B 1 345 ? 216.153 234.243 256.237 1.00 71.04  ? 345 LYS B CG  1 
ATOM   8848  C  CD  . LYS B 1 345 ? 217.070 235.451 256.149 1.00 71.04  ? 345 LYS B CD  1 
ATOM   8849  C  CE  . LYS B 1 345 ? 218.439 235.068 255.609 1.00 71.04  ? 345 LYS B CE  1 
ATOM   8850  N  NZ  . LYS B 1 345 ? 218.370 234.609 254.195 1.00 71.04  ? 345 LYS B NZ  1 
ATOM   8851  N  N   . THR B 1 346 ? 213.985 232.431 259.212 1.00 79.67  ? 346 THR B N   1 
ATOM   8852  C  CA  . THR B 1 346 ? 212.647 232.737 259.696 1.00 79.67  ? 346 THR B CA  1 
ATOM   8853  C  C   . THR B 1 346 ? 212.755 233.356 261.080 1.00 79.67  ? 346 THR B C   1 
ATOM   8854  O  O   . THR B 1 346 ? 213.697 233.078 261.822 1.00 79.67  ? 346 THR B O   1 
ATOM   8855  C  CB  . THR B 1 346 ? 211.769 231.481 259.733 1.00 79.67  ? 346 THR B CB  1 
ATOM   8856  O  OG1 . THR B 1 346 ? 211.858 230.803 258.475 1.00 79.67  ? 346 THR B OG1 1 
ATOM   8857  C  CG2 . THR B 1 346 ? 210.315 231.837 259.997 1.00 79.67  ? 346 THR B CG2 1 
ATOM   8858  N  N   . SER B 1 347 ? 211.790 234.211 261.410 1.00 87.46  ? 347 SER B N   1 
ATOM   8859  C  CA  . SER B 1 347 ? 211.782 234.861 262.713 1.00 87.46  ? 347 SER B CA  1 
ATOM   8860  C  C   . SER B 1 347 ? 211.702 233.825 263.825 1.00 87.46  ? 347 SER B C   1 
ATOM   8861  O  O   . SER B 1 347 ? 210.956 232.847 263.734 1.00 87.46  ? 347 SER B O   1 
ATOM   8862  C  CB  . SER B 1 347 ? 210.607 235.833 262.812 1.00 87.46  ? 347 SER B CB  1 
ATOM   8863  O  OG  . SER B 1 347 ? 209.378 235.169 262.582 1.00 87.46  ? 347 SER B OG  1 
ATOM   8864  N  N   . SER B 1 348 ? 212.489 234.041 264.878 1.00 91.81  ? 348 SER B N   1 
ATOM   8865  C  CA  . SER B 1 348 ? 212.506 233.116 266.002 1.00 91.81  ? 348 SER B CA  1 
ATOM   8866  C  C   . SER B 1 348 ? 211.157 233.109 266.710 1.00 91.81  ? 348 SER B C   1 
ATOM   8867  O  O   . SER B 1 348 ? 210.527 234.152 266.898 1.00 91.81  ? 348 SER B O   1 
ATOM   8868  C  CB  . SER B 1 348 ? 213.615 233.495 266.984 1.00 91.81  ? 348 SER B CB  1 
ATOM   8869  O  OG  . SER B 1 348 ? 213.512 234.856 267.367 1.00 91.81  ? 348 SER B OG  1 
ATOM   8870  N  N   . GLY B 1 349 ? 210.714 231.919 267.102 1.00 89.19  ? 349 GLY B N   1 
ATOM   8871  C  CA  . GLY B 1 349 ? 209.421 231.772 267.732 1.00 89.19  ? 349 GLY B CA  1 
ATOM   8872  C  C   . GLY B 1 349 ? 208.250 231.746 266.781 1.00 89.19  ? 349 GLY B C   1 
ATOM   8873  O  O   . GLY B 1 349 ? 207.103 231.699 267.239 1.00 89.19  ? 349 GLY B O   1 
ATOM   8874  N  N   . ALA B 1 350 ? 208.496 231.772 265.471 1.00 87.61  ? 350 ALA B N   1 
ATOM   8875  C  CA  . ALA B 1 350 ? 207.404 231.734 264.507 1.00 87.61  ? 350 ALA B CA  1 
ATOM   8876  C  C   . ALA B 1 350 ? 206.864 230.317 264.348 1.00 87.61  ? 350 ALA B C   1 
ATOM   8877  O  O   . ALA B 1 350 ? 205.675 230.064 264.567 1.00 87.61  ? 350 ALA B O   1 
ATOM   8878  C  CB  . ALA B 1 350 ? 207.869 232.290 263.160 1.00 87.61  ? 350 ALA B CB  1 
ATOM   8879  N  N   . GLU B 1 351 ? 207.728 229.380 263.967 1.00 82.14  ? 351 GLU B N   1 
ATOM   8880  C  CA  . GLU B 1 351 ? 207.358 227.980 263.846 1.00 82.14  ? 351 GLU B CA  1 
ATOM   8881  C  C   . GLU B 1 351 ? 208.366 227.124 264.597 1.00 82.14  ? 351 GLU B C   1 
ATOM   8882  O  O   . GLU B 1 351 ? 209.519 227.517 264.792 1.00 82.14  ? 351 GLU B O   1 
ATOM   8883  C  CB  . GLU B 1 351 ? 207.276 227.544 262.384 1.00 82.14  ? 351 GLU B CB  1 
ATOM   8884  C  CG  . GLU B 1 351 ? 206.022 228.019 261.679 1.00 82.14  ? 351 GLU B CG  1 
ATOM   8885  C  CD  . GLU B 1 351 ? 206.187 229.392 261.059 1.00 82.14  ? 351 GLU B CD  1 
ATOM   8886  O  OE1 . GLU B 1 351 ? 207.327 229.901 261.036 1.00 82.14  ? 351 GLU B OE1 1 
ATOM   8887  O  OE2 . GLU B 1 351 ? 205.178 229.964 260.595 1.00 82.14  ? 351 GLU B OE2 1 
ATOM   8888  N  N   . THR B 1 352 ? 207.915 225.947 265.018 1.00 71.59  ? 352 THR B N   1 
ATOM   8889  C  CA  . THR B 1 352 ? 208.729 225.087 265.861 1.00 71.59  ? 352 THR B CA  1 
ATOM   8890  C  C   . THR B 1 352 ? 209.902 224.495 265.085 1.00 71.59  ? 352 THR B C   1 
ATOM   8891  O  O   . THR B 1 352 ? 209.855 224.319 263.860 1.00 71.59  ? 352 THR B O   1 
ATOM   8892  C  CB  . THR B 1 352 ? 207.878 223.968 266.451 1.00 71.59  ? 352 THR B CB  1 
ATOM   8893  O  OG1 . THR B 1 352 ? 207.500 223.055 265.416 1.00 71.59  ? 352 THR B OG1 1 
ATOM   8894  C  CG2 . THR B 1 352 ? 206.629 224.542 267.084 1.00 71.59  ? 352 THR B CG2 1 
ATOM   8895  N  N   . SER B 1 353 ? 210.962 224.172 265.831 1.00 68.23  ? 353 SER B N   1 
ATOM   8896  C  CA  . SER B 1 353 ? 212.190 223.680 265.219 1.00 68.23  ? 353 SER B CA  1 
ATOM   8897  C  C   . SER B 1 353 ? 211.959 222.367 264.481 1.00 68.23  ? 353 SER B C   1 
ATOM   8898  O  O   . SER B 1 353 ? 212.490 222.163 263.383 1.00 68.23  ? 353 SER B O   1 
ATOM   8899  C  CB  . SER B 1 353 ? 213.267 223.518 266.289 1.00 68.23  ? 353 SER B CB  1 
ATOM   8900  O  OG  . SER B 1 353 ? 214.511 223.169 265.709 1.00 68.23  ? 353 SER B OG  1 
ATOM   8901  N  N   . ALA B 1 354 ? 211.166 221.466 265.064 1.00 61.49  ? 354 ALA B N   1 
ATOM   8902  C  CA  . ALA B 1 354 ? 210.873 220.200 264.406 1.00 61.49  ? 354 ALA B CA  1 
ATOM   8903  C  C   . ALA B 1 354 ? 210.134 220.394 263.093 1.00 61.49  ? 354 ALA B C   1 
ATOM   8904  O  O   . ALA B 1 354 ? 210.425 219.694 262.116 1.00 61.49  ? 354 ALA B O   1 
ATOM   8905  C  CB  . ALA B 1 354 ? 210.058 219.302 265.333 1.00 61.49  ? 354 ALA B CB  1 
ATOM   8906  N  N   . PHE B 1 355 ? 209.179 221.317 263.049 1.00 60.22  ? 355 PHE B N   1 
ATOM   8907  C  CA  . PHE B 1 355 ? 208.459 221.620 261.822 1.00 60.22  ? 355 PHE B CA  1 
ATOM   8908  C  C   . PHE B 1 355 ? 209.367 222.206 260.750 1.00 60.22  ? 355 PHE B C   1 
ATOM   8909  O  O   . PHE B 1 355 ? 209.281 221.810 259.575 1.00 60.22  ? 355 PHE B O   1 
ATOM   8910  C  CB  . PHE B 1 355 ? 207.314 222.579 262.127 1.00 60.22  ? 355 PHE B CB  1 
ATOM   8911  C  CG  . PHE B 1 355 ? 206.338 222.718 261.017 1.00 60.22  ? 355 PHE B CG  1 
ATOM   8912  C  CD1 . PHE B 1 355 ? 205.874 221.609 260.349 1.00 60.22  ? 355 PHE B CD1 1 
ATOM   8913  C  CD2 . PHE B 1 355 ? 205.872 223.961 260.645 1.00 60.22  ? 355 PHE B CD2 1 
ATOM   8914  C  CE1 . PHE B 1 355 ? 204.970 221.736 259.324 1.00 60.22  ? 355 PHE B CE1 1 
ATOM   8915  C  CE2 . PHE B 1 355 ? 204.969 224.093 259.623 1.00 60.22  ? 355 PHE B CE2 1 
ATOM   8916  C  CZ  . PHE B 1 355 ? 204.516 222.979 258.961 1.00 60.22  ? 355 PHE B CZ  1 
ATOM   8917  N  N   . ILE B 1 356 ? 210.247 223.134 261.135 1.00 58.59  ? 356 ILE B N   1 
ATOM   8918  C  CA  . ILE B 1 356 ? 211.229 223.636 260.179 1.00 58.59  ? 356 ILE B CA  1 
ATOM   8919  C  C   . ILE B 1 356 ? 212.077 222.489 259.650 1.00 58.59  ? 356 ILE B C   1 
ATOM   8920  O  O   . ILE B 1 356 ? 212.391 222.428 258.457 1.00 58.59  ? 356 ILE B O   1 
ATOM   8921  C  CB  . ILE B 1 356 ? 212.105 224.729 260.815 1.00 58.59  ? 356 ILE B CB  1 
ATOM   8922  C  CG1 . ILE B 1 356 ? 211.251 225.815 261.460 1.00 58.59  ? 356 ILE B CG1 1 
ATOM   8923  C  CG2 . ILE B 1 356 ? 213.007 225.342 259.767 1.00 58.59  ? 356 ILE B CG2 1 
ATOM   8924  C  CD1 . ILE B 1 356 ? 210.548 226.706 260.478 1.00 58.59  ? 356 ILE B CD1 1 
ATOM   8925  N  N   . GLU B 1 357 ? 212.456 221.558 260.529 1.00 59.60  ? 357 GLU B N   1 
ATOM   8926  C  CA  . GLU B 1 357 ? 213.295 220.436 260.117 1.00 59.60  ? 357 GLU B CA  1 
ATOM   8927  C  C   . GLU B 1 357 ? 212.575 219.528 259.125 1.00 59.60  ? 357 GLU B C   1 
ATOM   8928  O  O   . GLU B 1 357 ? 213.174 219.047 258.156 1.00 59.60  ? 357 GLU B O   1 
ATOM   8929  C  CB  . GLU B 1 357 ? 213.743 219.651 261.348 1.00 59.60  ? 357 GLU B CB  1 
ATOM   8930  C  CG  . GLU B 1 357 ? 214.449 218.344 261.048 1.00 59.60  ? 357 GLU B CG  1 
ATOM   8931  C  CD  . GLU B 1 357 ? 215.880 218.532 260.586 1.00 59.60  ? 357 GLU B CD  1 
ATOM   8932  O  OE1 . GLU B 1 357 ? 216.334 219.690 260.483 1.00 59.60  ? 357 GLU B OE1 1 
ATOM   8933  O  OE2 . GLU B 1 357 ? 216.555 217.515 260.326 1.00 59.60  ? 357 GLU B OE2 1 
ATOM   8934  N  N   . ARG B 1 358 ? 211.290 219.264 259.363 1.00 56.47  ? 358 ARG B N   1 
ATOM   8935  C  CA  . ARG B 1 358 ? 210.529 218.435 258.430 1.00 56.47  ? 358 ARG B CA  1 
ATOM   8936  C  C   . ARG B 1 358 ? 210.429 219.097 257.064 1.00 56.47  ? 358 ARG B C   1 
ATOM   8937  O  O   . ARG B 1 358 ? 210.608 218.436 256.026 1.00 56.47  ? 358 ARG B O   1 
ATOM   8938  C  CB  . ARG B 1 358 ? 209.136 218.153 258.986 1.00 56.47  ? 358 ARG B CB  1 
ATOM   8939  C  CG  . ARG B 1 358 ? 209.110 217.095 260.063 1.00 56.47  ? 358 ARG B CG  1 
ATOM   8940  C  CD  . ARG B 1 358 ? 207.795 217.101 260.818 1.00 56.47  ? 358 ARG B CD  1 
ATOM   8941  N  NE  . ARG B 1 358 ? 206.666 216.758 259.966 1.00 56.47  ? 358 ARG B NE  1 
ATOM   8942  C  CZ  . ARG B 1 358 ? 206.225 215.523 259.773 1.00 56.47  ? 358 ARG B CZ  1 
ATOM   8943  N  NH1 . ARG B 1 358 ? 206.809 214.485 260.346 1.00 56.47  ? 358 ARG B NH1 1 
ATOM   8944  N  NH2 . ARG B 1 358 ? 205.170 215.326 258.989 1.00 56.47  ? 358 ARG B NH2 1 
ATOM   8945  N  N   . VAL B 1 359 ? 210.135 220.400 257.040 1.00 55.25  ? 359 VAL B N   1 
ATOM   8946  C  CA  . VAL B 1 359 ? 210.063 221.091 255.756 1.00 55.25  ? 359 VAL B CA  1 
ATOM   8947  C  C   . VAL B 1 359 ? 211.419 221.063 255.067 1.00 55.25  ? 359 VAL B C   1 
ATOM   8948  O  O   . VAL B 1 359 ? 211.506 220.902 253.845 1.00 55.25  ? 359 VAL B O   1 
ATOM   8949  C  CB  . VAL B 1 359 ? 209.538 222.524 255.938 1.00 55.25  ? 359 VAL B CB  1 
ATOM   8950  C  CG1 . VAL B 1 359 ? 209.835 223.357 254.709 1.00 55.25  ? 359 VAL B CG1 1 
ATOM   8951  C  CG2 . VAL B 1 359 ? 208.048 222.501 256.194 1.00 55.25  ? 359 VAL B CG2 1 
ATOM   8952  N  N   . ALA B 1 360 ? 212.497 221.180 255.840 1.00 54.84  ? 360 ALA B N   1 
ATOM   8953  C  CA  . ALA B 1 360 ? 213.829 221.116 255.256 1.00 54.84  ? 360 ALA B CA  1 
ATOM   8954  C  C   . ALA B 1 360 ? 214.094 219.760 254.622 1.00 54.84  ? 360 ALA B C   1 
ATOM   8955  O  O   . ALA B 1 360 ? 214.632 219.683 253.514 1.00 54.84  ? 360 ALA B O   1 
ATOM   8956  C  CB  . ALA B 1 360 ? 214.884 221.423 256.314 1.00 54.84  ? 360 ALA B CB  1 
ATOM   8957  N  N   . ASP B 1 361 ? 213.726 218.677 255.309 1.00 53.66  ? 361 ASP B N   1 
ATOM   8958  C  CA  . ASP B 1 361 ? 213.971 217.343 254.764 1.00 53.66  ? 361 ASP B CA  1 
ATOM   8959  C  C   . ASP B 1 361 ? 213.190 217.121 253.476 1.00 53.66  ? 361 ASP B C   1 
ATOM   8960  O  O   . ASP B 1 361 ? 213.739 216.633 252.478 1.00 53.66  ? 361 ASP B O   1 
ATOM   8961  C  CB  . ASP B 1 361 ? 213.621 216.275 255.796 1.00 53.66  ? 361 ASP B CB  1 
ATOM   8962  C  CG  . ASP B 1 361 ? 214.689 216.118 256.855 1.00 53.66  ? 361 ASP B CG  1 
ATOM   8963  O  OD1 . ASP B 1 361 ? 215.870 216.386 256.554 1.00 53.66  ? 361 ASP B OD1 1 
ATOM   8964  O  OD2 . ASP B 1 361 ? 214.350 215.721 257.989 1.00 53.66  ? 361 ASP B OD2 1 
ATOM   8965  N  N   . ILE B 1 362 ? 211.911 217.497 253.468 1.00 51.45  ? 362 ILE B N   1 
ATOM   8966  C  CA  . ILE B 1 362 ? 211.103 217.304 252.265 1.00 51.45  ? 362 ILE B CA  1 
ATOM   8967  C  C   . ILE B 1 362 ? 211.648 218.140 251.109 1.00 51.45  ? 362 ILE B C   1 
ATOM   8968  O  O   . ILE B 1 362 ? 211.807 217.650 249.981 1.00 51.45  ? 362 ILE B O   1 
ATOM   8969  C  CB  . ILE B 1 362 ? 209.630 217.627 252.550 1.00 51.45  ? 362 ILE B CB  1 
ATOM   8970  C  CG1 . ILE B 1 362 ? 209.103 216.705 253.631 1.00 51.45  ? 362 ILE B CG1 1 
ATOM   8971  C  CG2 . ILE B 1 362 ? 208.817 217.453 251.300 1.00 51.45  ? 362 ILE B CG2 1 
ATOM   8972  C  CD1 . ILE B 1 362 ? 209.276 215.258 253.297 1.00 51.45  ? 362 ILE B CD1 1 
ATOM   8973  N  N   . SER B 1 363 ? 211.953 219.412 251.373 1.00 52.17  ? 363 SER B N   1 
ATOM   8974  C  CA  . SER B 1 363 ? 212.455 220.281 250.317 1.00 52.17  ? 363 SER B CA  1 
ATOM   8975  C  C   . SER B 1 363 ? 213.791 219.795 249.777 1.00 52.17  ? 363 SER B C   1 
ATOM   8976  O  O   . SER B 1 363 ? 214.033 219.851 248.568 1.00 52.17  ? 363 SER B O   1 
ATOM   8977  C  CB  . SER B 1 363 ? 212.580 221.707 250.834 1.00 52.17  ? 363 SER B CB  1 
ATOM   8978  O  OG  . SER B 1 363 ? 213.451 221.764 251.948 1.00 52.17  ? 363 SER B OG  1 
ATOM   8979  N  N   . GLN B 1 364 ? 214.682 219.339 250.655 1.00 50.93  ? 364 GLN B N   1 
ATOM   8980  C  CA  . GLN B 1 364 ? 215.956 218.791 250.210 1.00 50.93  ? 364 GLN B CA  1 
ATOM   8981  C  C   . GLN B 1 364 ? 215.749 217.589 249.304 1.00 50.93  ? 364 GLN B C   1 
ATOM   8982  O  O   . GLN B 1 364 ? 216.348 217.489 248.222 1.00 50.93  ? 364 GLN B O   1 
ATOM   8983  C  CB  . GLN B 1 364 ? 216.791 218.402 251.425 1.00 50.93  ? 364 GLN B CB  1 
ATOM   8984  C  CG  . GLN B 1 364 ? 218.128 217.812 251.096 1.00 50.93  ? 364 GLN B CG  1 
ATOM   8985  C  CD  . GLN B 1 364 ? 218.895 217.424 252.336 1.00 50.93  ? 364 GLN B CD  1 
ATOM   8986  O  OE1 . GLN B 1 364 ? 218.404 217.576 253.453 1.00 50.93  ? 364 GLN B OE1 1 
ATOM   8987  N  NE2 . GLN B 1 364 ? 220.100 216.902 252.149 1.00 50.93  ? 364 GLN B NE2 1 
ATOM   8988  N  N   . HIS B 1 365 ? 214.894 216.664 249.732 1.00 53.89  ? 365 HIS B N   1 
ATOM   8989  C  CA  . HIS B 1 365 ? 214.715 215.432 248.987 1.00 53.89  ? 365 HIS B CA  1 
ATOM   8990  C  C   . HIS B 1 365 ? 213.916 215.638 247.714 1.00 53.89  ? 365 HIS B C   1 
ATOM   8991  O  O   . HIS B 1 365 ? 213.837 214.712 246.904 1.00 53.89  ? 365 HIS B O   1 
ATOM   8992  C  CB  . HIS B 1 365 ? 214.060 214.388 249.890 1.00 53.89  ? 365 HIS B CB  1 
ATOM   8993  C  CG  . HIS B 1 365 ? 214.914 213.988 251.058 1.00 53.89  ? 365 HIS B CG  1 
ATOM   8994  N  ND1 . HIS B 1 365 ? 214.759 212.792 251.723 1.00 53.89  ? 365 HIS B ND1 1 
ATOM   8995  C  CD2 . HIS B 1 365 ? 215.944 214.623 251.668 1.00 53.89  ? 365 HIS B CD2 1 
ATOM   8996  C  CE1 . HIS B 1 365 ? 215.648 212.709 252.695 1.00 53.89  ? 365 HIS B CE1 1 
ATOM   8997  N  NE2 . HIS B 1 365 ? 216.380 213.808 252.684 1.00 53.89  ? 365 HIS B NE2 1 
ATOM   8998  N  N   . MET B 1 366 ? 213.312 216.815 247.528 1.00 56.15  ? 366 MET B N   1 
ATOM   8999  C  CA  . MET B 1 366 ? 212.744 217.159 246.225 1.00 56.15  ? 366 MET B CA  1 
ATOM   9000  C  C   . MET B 1 366 ? 213.713 217.937 245.337 1.00 56.15  ? 366 MET B C   1 
ATOM   9001  O  O   . MET B 1 366 ? 213.723 217.754 244.111 1.00 56.15  ? 366 MET B O   1 
ATOM   9002  C  CB  . MET B 1 366 ? 211.460 217.964 246.397 1.00 56.15  ? 366 MET B CB  1 
ATOM   9003  C  CG  . MET B 1 366 ? 210.412 217.267 247.218 1.00 56.15  ? 366 MET B CG  1 
ATOM   9004  S  SD  . MET B 1 366 ? 209.773 215.809 246.397 1.00 56.15  ? 366 MET B SD  1 
ATOM   9005  C  CE  . MET B 1 366 ? 210.583 214.502 247.316 1.00 56.15  ? 366 MET B CE  1 
ATOM   9006  N  N   . ALA B 1 367 ? 214.523 218.819 245.924 1.00 52.65  ? 367 ALA B N   1 
ATOM   9007  C  CA  . ALA B 1 367 ? 215.522 219.532 245.139 1.00 52.65  ? 367 ALA B CA  1 
ATOM   9008  C  C   . ALA B 1 367 ? 216.544 218.576 244.553 1.00 52.65  ? 367 ALA B C   1 
ATOM   9009  O  O   . ALA B 1 367 ? 217.079 218.828 243.467 1.00 52.65  ? 367 ALA B O   1 
ATOM   9010  C  CB  . ALA B 1 367 ? 216.211 220.588 245.998 1.00 52.65  ? 367 ALA B CB  1 
ATOM   9011  N  N   . ALA B 1 368 ? 216.826 217.474 245.248 1.00 53.01  ? 368 ALA B N   1 
ATOM   9012  C  CA  . ALA B 1 368 ? 217.700 216.463 244.664 1.00 53.01  ? 368 ALA B CA  1 
ATOM   9013  C  C   . ALA B 1 368 ? 217.115 215.916 243.366 1.00 53.01  ? 368 ALA B C   1 
ATOM   9014  O  O   . ALA B 1 368 ? 217.833 215.744 242.372 1.00 53.01  ? 368 ALA B O   1 
ATOM   9015  C  CB  . ALA B 1 368 ? 217.943 215.336 245.664 1.00 53.01  ? 368 ALA B CB  1 
ATOM   9016  N  N   . LEU B 1 369 ? 215.806 215.655 243.349 1.00 54.11  ? 369 LEU B N   1 
ATOM   9017  C  CA  . LEU B 1 369 ? 215.168 215.165 242.132 1.00 54.11  ? 369 LEU B CA  1 
ATOM   9018  C  C   . LEU B 1 369 ? 215.165 216.229 241.045 1.00 54.11  ? 369 LEU B C   1 
ATOM   9019  O  O   . LEU B 1 369 ? 215.308 215.912 239.859 1.00 54.11  ? 369 LEU B O   1 
ATOM   9020  C  CB  . LEU B 1 369 ? 213.745 214.702 242.429 1.00 54.11  ? 369 LEU B CB  1 
ATOM   9021  C  CG  . LEU B 1 369 ? 213.649 213.498 243.363 1.00 54.11  ? 369 LEU B CG  1 
ATOM   9022  C  CD1 . LEU B 1 369 ? 212.248 212.926 243.366 1.00 54.11  ? 369 LEU B CD1 1 
ATOM   9023  C  CD2 . LEU B 1 369 ? 214.663 212.438 242.981 1.00 54.11  ? 369 LEU B CD2 1 
ATOM   9024  N  N   . ALA B 1 370 ? 214.993 217.495 241.429 1.00 54.93  ? 370 ALA B N   1 
ATOM   9025  C  CA  . ALA B 1 370 ? 215.071 218.574 240.446 1.00 54.93  ? 370 ALA B CA  1 
ATOM   9026  C  C   . ALA B 1 370 ? 216.445 218.615 239.786 1.00 54.93  ? 370 ALA B C   1 
ATOM   9027  O  O   . ALA B 1 370 ? 216.559 218.751 238.562 1.00 54.93  ? 370 ALA B O   1 
ATOM   9028  C  CB  . ALA B 1 370 ? 214.751 219.913 241.106 1.00 54.93  ? 370 ALA B CB  1 
ATOM   9029  N  N   . LEU B 1 371 ? 217.504 218.489 240.587 1.00 56.15  ? 371 LEU B N   1 
ATOM   9030  C  CA  . LEU B 1 371 ? 218.852 218.460 240.029 1.00 56.15  ? 371 LEU B CA  1 
ATOM   9031  C  C   . LEU B 1 371 ? 219.049 217.259 239.120 1.00 56.15  ? 371 LEU B C   1 
ATOM   9032  O  O   . LEU B 1 371 ? 219.672 217.374 238.058 1.00 56.15  ? 371 LEU B O   1 
ATOM   9033  C  CB  . LEU B 1 371 ? 219.898 218.442 241.141 1.00 56.15  ? 371 LEU B CB  1 
ATOM   9034  C  CG  . LEU B 1 371 ? 220.486 219.765 241.630 1.00 56.15  ? 371 LEU B CG  1 
ATOM   9035  C  CD1 . LEU B 1 371 ? 221.235 220.464 240.506 1.00 56.15  ? 371 LEU B CD1 1 
ATOM   9036  C  CD2 . LEU B 1 371 ? 219.429 220.663 242.211 1.00 56.15  ? 371 LEU B CD2 1 
ATOM   9037  N  N   . GLU B 1 372 ? 218.545 216.094 239.524 1.00 58.76  ? 372 GLU B N   1 
ATOM   9038  C  CA  . GLU B 1 372 ? 218.698 214.912 238.681 1.00 58.76  ? 372 GLU B CA  1 
ATOM   9039  C  C   . GLU B 1 372 ? 217.994 215.096 237.345 1.00 58.76  ? 372 GLU B C   1 
ATOM   9040  O  O   . GLU B 1 372 ? 218.534 214.732 236.292 1.00 58.76  ? 372 GLU B O   1 
ATOM   9041  C  CB  . GLU B 1 372 ? 218.169 213.675 239.401 1.00 58.76  ? 372 GLU B CB  1 
ATOM   9042  C  CG  . GLU B 1 372 ? 218.549 212.366 238.735 1.00 58.76  ? 372 GLU B CG  1 
ATOM   9043  C  CD  . GLU B 1 372 ? 217.503 211.884 237.749 1.00 58.76  ? 372 GLU B CD  1 
ATOM   9044  O  OE1 . GLU B 1 372 ? 216.305 212.163 237.969 1.00 58.76  ? 372 GLU B OE1 1 
ATOM   9045  O  OE2 . GLU B 1 372 ? 217.878 211.229 236.755 1.00 58.76  ? 372 GLU B OE2 1 
ATOM   9046  N  N   . GLN B 1 373 ? 216.789 215.663 237.366 1.00 61.50  ? 373 GLN B N   1 
ATOM   9047  C  CA  . GLN B 1 373 ? 216.066 215.887 236.122 1.00 61.50  ? 373 GLN B CA  1 
ATOM   9048  C  C   . GLN B 1 373 ? 216.789 216.887 235.235 1.00 61.50  ? 373 GLN B C   1 
ATOM   9049  O  O   . GLN B 1 373 ? 216.868 216.698 234.018 1.00 61.50  ? 373 GLN B O   1 
ATOM   9050  C  CB  . GLN B 1 373 ? 214.644 216.352 236.412 1.00 61.50  ? 373 GLN B CB  1 
ATOM   9051  C  CG  . GLN B 1 373 ? 213.749 215.230 236.867 1.00 61.50  ? 373 GLN B CG  1 
ATOM   9052  C  CD  . GLN B 1 373 ? 213.826 214.040 235.937 1.00 61.50  ? 373 GLN B CD  1 
ATOM   9053  O  OE1 . GLN B 1 373 ? 213.404 214.111 234.785 1.00 61.50  ? 373 GLN B OE1 1 
ATOM   9054  N  NE2 . GLN B 1 373 ? 214.373 212.937 236.434 1.00 61.50  ? 373 GLN B NE2 1 
ATOM   9055  N  N   . GLU B 1 374 ? 217.327 217.956 235.821 1.00 62.03  ? 374 GLU B N   1 
ATOM   9056  C  CA  . GLU B 1 374 ? 218.066 218.921 235.013 1.00 62.03  ? 374 GLU B CA  1 
ATOM   9057  C  C   . GLU B 1 374 ? 219.319 218.297 234.409 1.00 62.03  ? 374 GLU B C   1 
ATOM   9058  O  O   . GLU B 1 374 ? 219.660 218.571 233.253 1.00 62.03  ? 374 GLU B O   1 
ATOM   9059  C  CB  . GLU B 1 374 ? 218.423 220.145 235.848 1.00 62.03  ? 374 GLU B CB  1 
ATOM   9060  C  CG  . GLU B 1 374 ? 218.952 221.296 235.030 1.00 62.03  ? 374 GLU B CG  1 
ATOM   9061  C  CD  . GLU B 1 374 ? 220.456 221.276 234.924 1.00 62.03  ? 374 GLU B CD  1 
ATOM   9062  O  OE1 . GLU B 1 374 ? 221.121 221.091 235.962 1.00 62.03  ? 374 GLU B OE1 1 
ATOM   9063  O  OE2 . GLU B 1 374 ? 220.976 221.440 233.801 1.00 62.03  ? 374 GLU B OE2 1 
ATOM   9064  N  N   . LYS B 1 375 ? 220.022 217.463 235.176 1.00 62.09  ? 375 LYS B N   1 
ATOM   9065  C  CA  . LYS B 1 375 ? 221.221 216.815 234.656 1.00 62.09  ? 375 LYS B CA  1 
ATOM   9066  C  C   . LYS B 1 375 ? 220.883 215.878 233.506 1.00 62.09  ? 375 LYS B C   1 
ATOM   9067  O  O   . LYS B 1 375 ? 221.557 215.879 232.466 1.00 62.09  ? 375 LYS B O   1 
ATOM   9068  C  CB  . LYS B 1 375 ? 221.931 216.056 235.773 1.00 62.09  ? 375 LYS B CB  1 
ATOM   9069  C  CG  . LYS B 1 375 ? 223.358 215.691 235.451 1.00 62.09  ? 375 LYS B CG  1 
ATOM   9070  C  CD  . LYS B 1 375 ? 224.274 216.887 235.617 1.00 62.09  ? 375 LYS B CD  1 
ATOM   9071  C  CE  . LYS B 1 375 ? 225.725 216.452 235.716 1.00 62.09  ? 375 LYS B CE  1 
ATOM   9072  N  NZ  . LYS B 1 375 ? 226.034 215.340 234.776 1.00 62.09  ? 375 LYS B NZ  1 
ATOM   9073  N  N   . SER B 1 376 ? 219.834 215.072 233.671 1.00 65.89  ? 376 SER B N   1 
ATOM   9074  C  CA  . SER B 1 376 ? 219.427 214.184 232.591 1.00 65.89  ? 376 SER B CA  1 
ATOM   9075  C  C   . SER B 1 376 ? 218.954 214.972 231.377 1.00 65.89  ? 376 SER B C   1 
ATOM   9076  O  O   . SER B 1 376 ? 219.185 214.554 230.236 1.00 65.89  ? 376 SER B O   1 
ATOM   9077  C  CB  . SER B 1 376 ? 218.336 213.232 233.078 1.00 65.89  ? 376 SER B CB  1 
ATOM   9078  O  OG  . SER B 1 376 ? 218.055 212.242 232.106 1.00 65.89  ? 376 SER B OG  1 
ATOM   9079  N  N   . ARG B 1 377 ? 218.302 216.114 231.599 1.00 67.49  ? 377 ARG B N   1 
ATOM   9080  C  CA  . ARG B 1 377 ? 217.860 216.952 230.489 1.00 67.49  ? 377 ARG B CA  1 
ATOM   9081  C  C   . ARG B 1 377 ? 219.047 217.505 229.713 1.00 67.49  ? 377 ARG B C   1 
ATOM   9082  O  O   . ARG B 1 377 ? 219.031 217.542 228.479 1.00 67.49  ? 377 ARG B O   1 
ATOM   9083  C  CB  . ARG B 1 377 ? 216.984 218.088 231.013 1.00 67.49  ? 377 ARG B CB  1 
ATOM   9084  C  CG  . ARG B 1 377 ? 216.189 218.801 229.946 1.00 67.49  ? 377 ARG B CG  1 
ATOM   9085  C  CD  . ARG B 1 377 ? 216.924 220.019 229.446 1.00 67.49  ? 377 ARG B CD  1 
ATOM   9086  N  NE  . ARG B 1 377 ? 217.112 221.007 230.498 1.00 67.49  ? 377 ARG B NE  1 
ATOM   9087  C  CZ  . ARG B 1 377 ? 218.081 221.910 230.505 1.00 67.49  ? 377 ARG B CZ  1 
ATOM   9088  N  NH1 . ARG B 1 377 ? 218.977 221.970 229.534 1.00 67.49  ? 377 ARG B NH1 1 
ATOM   9089  N  NH2 . ARG B 1 377 ? 218.155 222.775 231.513 1.00 67.49  ? 377 ARG B NH2 1 
ATOM   9090  N  N   . GLN B 1 378 ? 220.083 217.958 230.422 1.00 69.75  ? 378 GLN B N   1 
ATOM   9091  C  CA  . GLN B 1 378 ? 221.285 218.435 229.744 1.00 69.75  ? 378 GLN B CA  1 
ATOM   9092  C  C   . GLN B 1 378 ? 221.964 217.311 228.970 1.00 69.75  ? 378 GLN B C   1 
ATOM   9093  O  O   . GLN B 1 378 ? 222.460 217.523 227.855 1.00 69.75  ? 378 GLN B O   1 
ATOM   9094  C  CB  . GLN B 1 378 ? 222.248 219.048 230.758 1.00 69.75  ? 378 GLN B CB  1 
ATOM   9095  C  CG  . GLN B 1 378 ? 223.456 219.739 230.150 1.00 69.75  ? 378 GLN B CG  1 
ATOM   9096  C  CD  . GLN B 1 378 ? 224.599 218.778 229.858 1.00 69.75  ? 378 GLN B CD  1 
ATOM   9097  O  OE1 . GLN B 1 378 ? 224.665 217.681 230.416 1.00 69.75  ? 378 GLN B OE1 1 
ATOM   9098  N  NE2 . GLN B 1 378 ? 225.506 219.189 228.980 1.00 69.75  ? 378 GLN B NE2 1 
ATOM   9099  N  N   . HIS B 1 379 ? 222.007 216.110 229.553 1.00 71.10  ? 379 HIS B N   1 
ATOM   9100  C  CA  . HIS B 1 379 ? 222.593 214.969 228.854 1.00 71.10  ? 379 HIS B CA  1 
ATOM   9101  C  C   . HIS B 1 379 ? 221.816 214.633 227.586 1.00 71.10  ? 379 HIS B C   1 
ATOM   9102  O  O   . HIS B 1 379 ? 222.408 214.289 226.558 1.00 71.10  ? 379 HIS B O   1 
ATOM   9103  C  CB  . HIS B 1 379 ? 222.649 213.759 229.786 1.00 71.10  ? 379 HIS B CB  1 
ATOM   9104  C  CG  . HIS B 1 379 ? 223.533 212.656 229.293 1.00 71.10  ? 379 HIS B CG  1 
ATOM   9105  N  ND1 . HIS B 1 379 ? 223.171 211.815 228.263 1.00 71.10  ? 379 HIS B ND1 1 
ATOM   9106  C  CD2 . HIS B 1 379 ? 224.763 212.254 229.691 1.00 71.10  ? 379 HIS B CD2 1 
ATOM   9107  C  CE1 . HIS B 1 379 ? 224.140 210.944 228.047 1.00 71.10  ? 379 HIS B CE1 1 
ATOM   9108  N  NE2 . HIS B 1 379 ? 225.118 211.188 228.901 1.00 71.10  ? 379 HIS B NE2 1 
ATOM   9109  N  N   . ILE B 1 380 ? 220.487 214.709 227.647 1.00 71.65  ? 380 ILE B N   1 
ATOM   9110  C  CA  . ILE B 1 380 ? 219.661 214.512 226.458 1.00 71.65  ? 380 ILE B CA  1 
ATOM   9111  C  C   . ILE B 1 380 ? 219.924 215.607 225.431 1.00 71.65  ? 380 ILE B C   1 
ATOM   9112  O  O   . ILE B 1 380 ? 220.025 215.341 224.222 1.00 71.65  ? 380 ILE B O   1 
ATOM   9113  C  CB  . ILE B 1 380 ? 218.176 214.459 226.861 1.00 71.65  ? 380 ILE B CB  1 
ATOM   9114  C  CG1 . ILE B 1 380 ? 217.799 213.064 227.365 1.00 71.65  ? 380 ILE B CG1 1 
ATOM   9115  C  CG2 . ILE B 1 380 ? 217.281 214.900 225.715 1.00 71.65  ? 380 ILE B CG2 1 
ATOM   9116  C  CD1 . ILE B 1 380 ? 217.890 211.992 226.312 1.00 71.65  ? 380 ILE B CD1 1 
ATOM   9117  N  N   . GLU B 1 381 ? 220.025 216.855 225.893 1.00 74.63  ? 381 GLU B N   1 
ATOM   9118  C  CA  . GLU B 1 381 ? 220.184 217.985 224.985 1.00 74.63  ? 381 GLU B CA  1 
ATOM   9119  C  C   . GLU B 1 381 ? 221.498 217.908 224.225 1.00 74.63  ? 381 GLU B C   1 
ATOM   9120  O  O   . GLU B 1 381 ? 221.553 218.232 223.033 1.00 74.63  ? 381 GLU B O   1 
ATOM   9121  C  CB  . GLU B 1 381 ? 220.094 219.298 225.762 1.00 74.63  ? 381 GLU B CB  1 
ATOM   9122  C  CG  . GLU B 1 381 ? 218.674 219.722 226.101 1.00 74.63  ? 381 GLU B CG  1 
ATOM   9123  C  CD  . GLU B 1 381 ? 217.883 220.139 224.876 1.00 74.63  ? 381 GLU B CD  1 
ATOM   9124  O  OE1 . GLU B 1 381 ? 218.495 220.665 223.923 1.00 74.63  ? 381 GLU B OE1 1 
ATOM   9125  O  OE2 . GLU B 1 381 ? 216.651 219.939 224.867 1.00 74.63  ? 381 GLU B OE2 1 
ATOM   9126  N  N   . GLN B 1 382 ? 222.567 217.480 224.891 1.00 74.73  ? 382 GLN B N   1 
ATOM   9127  C  CA  . GLN B 1 382 ? 223.849 217.423 224.196 1.00 74.73  ? 382 GLN B CA  1 
ATOM   9128  C  C   . GLN B 1 382 ? 223.914 216.320 223.143 1.00 74.73  ? 382 GLN B C   1 
ATOM   9129  O  O   . GLN B 1 382 ? 224.897 216.278 222.395 1.00 74.73  ? 382 GLN B O   1 
ATOM   9130  C  CB  . GLN B 1 382 ? 224.989 217.240 225.199 1.00 74.73  ? 382 GLN B CB  1 
ATOM   9131  C  CG  . GLN B 1 382 ? 225.114 215.838 225.772 1.00 74.73  ? 382 GLN B CG  1 
ATOM   9132  C  CD  . GLN B 1 382 ? 226.045 214.958 224.960 1.00 74.73  ? 382 GLN B CD  1 
ATOM   9133  O  OE1 . GLN B 1 382 ? 226.926 215.451 224.256 1.00 74.73  ? 382 GLN B OE1 1 
ATOM   9134  N  NE2 . GLN B 1 382 ? 225.854 213.648 225.054 1.00 74.73  ? 382 GLN B NE2 1 
ATOM   9135  N  N   . LEU B 1 383 ? 222.925 215.423 223.071 1.00 74.92  ? 383 LEU B N   1 
ATOM   9136  C  CA  . LEU B 1 383 ? 222.993 214.275 222.170 1.00 74.92  ? 383 LEU B CA  1 
ATOM   9137  C  C   . LEU B 1 383 ? 221.900 214.271 221.108 1.00 74.92  ? 383 LEU B C   1 
ATOM   9138  O  O   . LEU B 1 383 ? 222.221 214.220 219.918 1.00 74.92  ? 383 LEU B O   1 
ATOM   9139  C  CB  . LEU B 1 383 ? 222.946 212.974 222.982 1.00 74.92  ? 383 LEU B CB  1 
ATOM   9140  C  CG  . LEU B 1 383 ? 223.334 211.692 222.242 1.00 74.92  ? 383 LEU B CG  1 
ATOM   9141  C  CD1 . LEU B 1 383 ? 224.054 210.734 223.176 1.00 74.92  ? 383 LEU B CD1 1 
ATOM   9142  C  CD2 . LEU B 1 383 ? 222.120 211.021 221.636 1.00 74.92  ? 383 LEU B CD2 1 
ATOM   9143  N  N   . ILE B 1 384 ? 220.621 214.314 221.495 1.00 71.90  ? 384 ILE B N   1 
ATOM   9144  C  CA  . ILE B 1 384 ? 219.525 213.946 220.593 1.00 71.90  ? 384 ILE B CA  1 
ATOM   9145  C  C   . ILE B 1 384 ? 219.513 214.777 219.312 1.00 71.90  ? 384 ILE B C   1 
ATOM   9146  O  O   . ILE B 1 384 ? 219.675 216.001 219.348 1.00 71.90  ? 384 ILE B O   1 
ATOM   9147  C  CB  . ILE B 1 384 ? 218.167 214.030 221.315 1.00 71.90  ? 384 ILE B CB  1 
ATOM   9148  C  CG1 . ILE B 1 384 ? 217.937 212.770 222.149 1.00 71.90  ? 384 ILE B CG1 1 
ATOM   9149  C  CG2 . ILE B 1 384 ? 217.032 214.247 220.340 1.00 71.90  ? 384 ILE B CG2 1 
ATOM   9150  C  CD1 . ILE B 1 384 ? 216.656 212.794 222.948 1.00 71.90  ? 384 ILE B CD1 1 
ATOM   9151  N  N   . GLN B 1 385 ? 219.314 214.104 218.173 1.00 69.64  ? 385 GLN B N   1 
ATOM   9152  C  CA  . GLN B 1 385 ? 219.400 214.690 216.839 1.00 69.64  ? 385 GLN B CA  1 
ATOM   9153  C  C   . GLN B 1 385 ? 218.043 215.060 216.250 1.00 69.64  ? 385 GLN B C   1 
ATOM   9154  O  O   . GLN B 1 385 ? 217.887 216.144 215.687 1.00 69.64  ? 385 GLN B O   1 
ATOM   9155  C  CB  . GLN B 1 385 ? 220.116 213.716 215.898 1.00 69.64  ? 385 GLN B CB  1 
ATOM   9156  C  CG  . GLN B 1 385 ? 221.499 213.321 216.367 1.00 69.64  ? 385 GLN B CG  1 
ATOM   9157  C  CD  . GLN B 1 385 ? 222.513 214.428 216.172 1.00 69.64  ? 385 GLN B CD  1 
ATOM   9158  O  OE1 . GLN B 1 385 ? 222.897 214.742 215.047 1.00 69.64  ? 385 GLN B OE1 1 
ATOM   9159  N  NE2 . GLN B 1 385 ? 222.954 215.027 217.271 1.00 69.64  ? 385 GLN B NE2 1 
ATOM   9160  N  N   . PHE B 1 386 ? 217.062 214.175 216.348 1.00 68.29  ? 386 PHE B N   1 
ATOM   9161  C  CA  . PHE B 1 386 ? 215.723 214.432 215.841 1.00 68.29  ? 386 PHE B CA  1 
ATOM   9162  C  C   . PHE B 1 386 ? 214.860 215.053 216.935 1.00 68.29  ? 386 PHE B C   1 
ATOM   9163  O  O   . PHE B 1 386 ? 215.356 215.508 217.967 1.00 68.29  ? 386 PHE B O   1 
ATOM   9164  C  CB  . PHE B 1 386 ? 215.089 213.141 215.321 1.00 68.29  ? 386 PHE B CB  1 
ATOM   9165  C  CG  . PHE B 1 386 ? 215.853 212.501 214.203 1.00 68.29  ? 386 PHE B CG  1 
ATOM   9166  C  CD1 . PHE B 1 386 ? 216.719 213.245 213.422 1.00 68.29  ? 386 PHE B CD1 1 
ATOM   9167  C  CD2 . PHE B 1 386 ? 215.703 211.152 213.930 1.00 68.29  ? 386 PHE B CD2 1 
ATOM   9168  C  CE1 . PHE B 1 386 ? 217.422 212.656 212.392 1.00 68.29  ? 386 PHE B CE1 1 
ATOM   9169  C  CE2 . PHE B 1 386 ? 216.401 210.560 212.903 1.00 68.29  ? 386 PHE B CE2 1 
ATOM   9170  C  CZ  . PHE B 1 386 ? 217.263 211.311 212.132 1.00 68.29  ? 386 PHE B CZ  1 
ATOM   9171  N  N   . ASP B 1 387 ? 213.546 215.084 216.693 1.00 69.87  ? 387 ASP B N   1 
ATOM   9172  C  CA  . ASP B 1 387 ? 212.616 215.673 217.653 1.00 69.87  ? 387 ASP B CA  1 
ATOM   9173  C  C   . ASP B 1 387 ? 211.212 215.099 217.491 1.00 69.87  ? 387 ASP B C   1 
ATOM   9174  O  O   . ASP B 1 387 ? 210.692 215.052 216.360 1.00 69.87  ? 387 ASP B O   1 
ATOM   9175  C  CB  . ASP B 1 387 ? 212.584 217.192 217.494 1.00 69.87  ? 387 ASP B CB  1 
ATOM   9176  C  CG  . ASP B 1 387 ? 212.280 217.900 218.787 1.00 69.87  ? 387 ASP B CG  1 
ATOM   9177  O  OD1 . ASP B 1 387 ? 212.360 217.253 219.849 1.00 69.87  ? 387 ASP B OD1 1 
ATOM   9178  O  OD2 . ASP B 1 387 ? 211.952 219.102 218.743 1.00 69.87  ? 387 ASP B OD2 1 
ATOM   9179  N  N   . PRO B 1 388 ? 210.579 214.642 218.579 1.00 65.36  ? 388 PRO B N   1 
ATOM   9180  C  CA  . PRO B 1 388 ? 209.179 214.199 218.472 1.00 65.36  ? 388 PRO B CA  1 
ATOM   9181  C  C   . PRO B 1 388 ? 208.250 215.280 217.958 1.00 65.36  ? 388 PRO B C   1 
ATOM   9182  O  O   . PRO B 1 388 ? 207.340 214.994 217.172 1.00 65.36  ? 388 PRO B O   1 
ATOM   9183  C  CB  . PRO B 1 388 ? 208.836 213.786 219.908 1.00 65.36  ? 388 PRO B CB  1 
ATOM   9184  C  CG  . PRO B 1 388 ? 210.143 213.433 220.514 1.00 65.36  ? 388 PRO B CG  1 
ATOM   9185  C  CD  . PRO B 1 388 ? 211.135 214.384 219.917 1.00 65.36  ? 388 PRO B CD  1 
ATOM   9186  N  N   . MET B 1 389 ? 208.452 216.521 218.373 1.00 70.92  ? 389 MET B N   1 
ATOM   9187  C  CA  . MET B 1 389 ? 207.785 217.627 217.711 1.00 70.92  ? 389 MET B CA  1 
ATOM   9188  C  C   . MET B 1 389 ? 208.488 217.895 216.387 1.00 70.92  ? 389 MET B C   1 
ATOM   9189  O  O   . MET B 1 389 ? 209.718 217.817 216.303 1.00 70.92  ? 389 MET B O   1 
ATOM   9190  C  CB  . MET B 1 389 ? 207.799 218.878 218.587 1.00 70.92  ? 389 MET B CB  1 
ATOM   9191  C  CG  . MET B 1 389 ? 206.972 220.022 218.023 1.00 70.92  ? 389 MET B CG  1 
ATOM   9192  S  SD  . MET B 1 389 ? 207.091 221.539 218.981 1.00 70.92  ? 389 MET B SD  1 
ATOM   9193  C  CE  . MET B 1 389 ? 208.734 222.080 218.529 1.00 70.92  ? 389 MET B CE  1 
ATOM   9194  N  N   . THR B 1 390 ? 207.703 218.190 215.352 1.00 64.83  ? 390 THR B N   1 
ATOM   9195  C  CA  . THR B 1 390 ? 208.099 218.603 214.011 1.00 64.83  ? 390 THR B CA  1 
ATOM   9196  C  C   . THR B 1 390 ? 208.664 217.461 213.173 1.00 64.83  ? 390 THR B C   1 
ATOM   9197  O  O   . THR B 1 390 ? 208.851 217.645 211.973 1.00 64.83  ? 390 THR B O   1 
ATOM   9198  C  CB  . THR B 1 390 ? 209.135 219.745 214.009 1.00 64.83  ? 390 THR B CB  1 
ATOM   9199  O  OG1 . THR B 1 390 ? 210.416 219.219 214.373 1.00 64.83  ? 390 THR B OG1 1 
ATOM   9200  C  CG2 . THR B 1 390 ? 208.758 220.821 214.990 1.00 64.83  ? 390 THR B CG2 1 
ATOM   9201  N  N   . GLY B 1 391 ? 208.940 216.294 213.747 1.00 65.03  ? 391 GLY B N   1 
ATOM   9202  C  CA  . GLY B 1 391 ? 209.498 215.185 212.996 1.00 65.03  ? 391 GLY B CA  1 
ATOM   9203  C  C   . GLY B 1 391 ? 210.813 215.452 212.279 1.00 65.03  ? 391 GLY B C   1 
ATOM   9204  O  O   . GLY B 1 391 ? 211.349 214.557 211.620 1.00 65.03  ? 391 GLY B O   1 
ATOM   9205  N  N   . LEU B 1 392 ? 211.351 216.676 212.400 1.00 66.69  ? 392 LEU B N   1 
ATOM   9206  C  CA  . LEU B 1 392 ? 212.515 217.148 211.665 1.00 66.69  ? 392 LEU B CA  1 
ATOM   9207  C  C   . LEU B 1 392 ? 213.766 217.095 212.524 1.00 66.69  ? 392 LEU B C   1 
ATOM   9208  O  O   . LEU B 1 392 ? 213.688 217.062 213.754 1.00 66.69  ? 392 LEU B O   1 
ATOM   9209  C  CB  . LEU B 1 392 ? 212.297 218.583 211.197 1.00 66.69  ? 392 LEU B CB  1 
ATOM   9210  C  CG  . LEU B 1 392 ? 211.546 218.846 209.897 1.00 66.69  ? 392 LEU B CG  1 
ATOM   9211  C  CD1 . LEU B 1 392 ? 211.348 220.343 209.740 1.00 66.69  ? 392 LEU B CD1 1 
ATOM   9212  C  CD2 . LEU B 1 392 ? 212.310 218.279 208.716 1.00 66.69  ? 392 LEU B CD2 1 
ATOM   9213  N  N   . PRO B 1 393 ? 214.942 217.077 211.904 1.00 66.80  ? 393 PRO B N   1 
ATOM   9214  C  CA  . PRO B 1 393 ? 216.174 217.206 212.683 1.00 66.80  ? 393 PRO B CA  1 
ATOM   9215  C  C   . PRO B 1 393 ? 216.240 218.557 213.377 1.00 66.80  ? 393 PRO B C   1 
ATOM   9216  O  O   . PRO B 1 393 ? 215.792 219.572 212.843 1.00 66.80  ? 393 PRO B O   1 
ATOM   9217  C  CB  . PRO B 1 393 ? 217.278 217.061 211.632 1.00 66.80  ? 393 PRO B CB  1 
ATOM   9218  C  CG  . PRO B 1 393 ? 216.637 216.359 210.500 1.00 66.80  ? 393 PRO B CG  1 
ATOM   9219  C  CD  . PRO B 1 393 ? 215.219 216.819 210.484 1.00 66.80  ? 393 PRO B CD  1 
ATOM   9220  N  N   . ASN B 1 394 ? 216.800 218.557 214.582 1.00 69.55  ? 394 ASN B N   1 
ATOM   9221  C  CA  . ASN B 1 394 ? 217.078 219.776 215.321 1.00 69.55  ? 394 ASN B CA  1 
ATOM   9222  C  C   . ASN B 1 394 ? 218.530 220.177 215.103 1.00 69.55  ? 394 ASN B C   1 
ATOM   9223  O  O   . ASN B 1 394 ? 219.265 219.527 214.354 1.00 69.55  ? 394 ASN B O   1 
ATOM   9224  C  CB  . ASN B 1 394 ? 216.783 219.592 216.810 1.00 69.55  ? 394 ASN B CB  1 
ATOM   9225  C  CG  . ASN B 1 394 ? 217.475 218.387 217.386 1.00 69.55  ? 394 ASN B CG  1 
ATOM   9226  O  OD1 . ASN B 1 394 ? 218.698 218.351 217.496 1.00 69.55  ? 394 ASN B OD1 1 
ATOM   9227  N  ND2 . ASN B 1 394 ? 216.697 217.373 217.730 1.00 69.55  ? 394 ASN B ND2 1 
ATOM   9228  N  N   . ARG B 1 395 ? 218.943 221.260 215.764 1.00 70.01  ? 395 ARG B N   1 
ATOM   9229  C  CA  . ARG B 1 395 ? 220.255 221.825 215.476 1.00 70.01  ? 395 ARG B CA  1 
ATOM   9230  C  C   . ARG B 1 395 ? 221.389 220.849 215.764 1.00 70.01  ? 395 ARG B C   1 
ATOM   9231  O  O   . ARG B 1 395 ? 222.484 221.000 215.204 1.00 70.01  ? 395 ARG B O   1 
ATOM   9232  C  CB  . ARG B 1 395 ? 220.478 223.113 216.266 1.00 70.01  ? 395 ARG B CB  1 
ATOM   9233  C  CG  . ARG B 1 395 ? 221.673 223.882 215.756 1.00 70.01  ? 395 ARG B CG  1 
ATOM   9234  C  CD  . ARG B 1 395 ? 221.562 225.375 215.947 1.00 70.01  ? 395 ARG B CD  1 
ATOM   9235  N  NE  . ARG B 1 395 ? 221.774 225.763 217.335 1.00 70.01  ? 395 ARG B NE  1 
ATOM   9236  C  CZ  . ARG B 1 395 ? 222.252 226.940 217.716 1.00 70.01  ? 395 ARG B CZ  1 
ATOM   9237  N  NH1 . ARG B 1 395 ? 222.569 227.875 216.835 1.00 70.01  ? 395 ARG B NH1 1 
ATOM   9238  N  NH2 . ARG B 1 395 ? 222.424 227.183 219.012 1.00 70.01  ? 395 ARG B NH2 1 
ATOM   9239  N  N   . ASN B 1 396 ? 221.158 219.844 216.607 1.00 72.57  ? 396 ASN B N   1 
ATOM   9240  C  CA  . ASN B 1 396 ? 222.200 218.859 216.875 1.00 72.57  ? 396 ASN B CA  1 
ATOM   9241  C  C   . ASN B 1 396 ? 222.560 218.036 215.647 1.00 72.57  ? 396 ASN B C   1 
ATOM   9242  O  O   . ASN B 1 396 ? 223.627 217.414 215.637 1.00 72.57  ? 396 ASN B O   1 
ATOM   9243  C  CB  . ASN B 1 396 ? 221.775 217.934 218.015 1.00 72.57  ? 396 ASN B CB  1 
ATOM   9244  C  CG  . ASN B 1 396 ? 221.812 218.620 219.368 1.00 72.57  ? 396 ASN B CG  1 
ATOM   9245  O  OD1 . ASN B 1 396 ? 222.412 219.685 219.521 1.00 72.57  ? 396 ASN B OD1 1 
ATOM   9246  N  ND2 . ASN B 1 396 ? 221.171 218.009 220.360 1.00 72.57  ? 396 ASN B ND2 1 
ATOM   9247  N  N   . ASN B 1 397 ? 221.704 218.012 214.628 1.00 67.69  ? 397 ASN B N   1 
ATOM   9248  C  CA  . ASN B 1 397 ? 222.014 217.406 213.339 1.00 67.69  ? 397 ASN B CA  1 
ATOM   9249  C  C   . ASN B 1 397 ? 222.475 218.425 212.312 1.00 67.69  ? 397 ASN B C   1 
ATOM   9250  O  O   . ASN B 1 397 ? 223.312 218.109 211.461 1.00 67.69  ? 397 ASN B O   1 
ATOM   9251  C  CB  . ASN B 1 397 ? 220.787 216.657 212.801 1.00 67.69  ? 397 ASN B CB  1 
ATOM   9252  C  CG  . ASN B 1 397 ? 221.157 215.461 211.947 1.00 67.69  ? 397 ASN B CG  1 
ATOM   9253  O  OD1 . ASN B 1 397 ? 222.325 215.235 211.647 1.00 67.69  ? 397 ASN B OD1 1 
ATOM   9254  N  ND2 . ASN B 1 397 ? 220.160 214.677 211.568 1.00 67.69  ? 397 ASN B ND2 1 
ATOM   9255  N  N   . LEU B 1 398 ? 221.951 219.650 212.384 1.00 67.71  ? 398 LEU B N   1 
ATOM   9256  C  CA  . LEU B 1 398 ? 222.409 220.705 211.489 1.00 67.71  ? 398 LEU B CA  1 
ATOM   9257  C  C   . LEU B 1 398 ? 223.886 220.990 211.693 1.00 67.71  ? 398 LEU B C   1 
ATOM   9258  O  O   . LEU B 1 398 ? 224.617 221.217 210.726 1.00 67.71  ? 398 LEU B O   1 
ATOM   9259  C  CB  . LEU B 1 398 ? 221.592 221.977 211.706 1.00 67.71  ? 398 LEU B CB  1 
ATOM   9260  C  CG  . LEU B 1 398 ? 222.010 223.216 210.916 1.00 67.71  ? 398 LEU B CG  1 
ATOM   9261  C  CD1 . LEU B 1 398 ? 220.785 223.927 210.433 1.00 67.71  ? 398 LEU B CD1 1 
ATOM   9262  C  CD2 . LEU B 1 398 ? 222.849 224.158 211.763 1.00 67.71  ? 398 LEU B CD2 1 
ATOM   9263  N  N   . HIS B 1 399 ? 224.341 221.006 212.944 1.00 69.09  ? 399 HIS B N   1 
ATOM   9264  C  CA  . HIS B 1 399 ? 225.763 221.206 213.190 1.00 69.09  ? 399 HIS B CA  1 
ATOM   9265  C  C   . HIS B 1 399 ? 226.584 220.145 212.473 1.00 69.09  ? 399 HIS B C   1 
ATOM   9266  O  O   . HIS B 1 399 ? 227.471 220.460 211.671 1.00 69.09  ? 399 HIS B O   1 
ATOM   9267  C  CB  . HIS B 1 399 ? 226.043 221.173 214.693 1.00 69.09  ? 399 HIS B CB  1 
ATOM   9268  C  CG  . HIS B 1 399 ? 225.504 222.353 215.439 1.00 69.09  ? 399 HIS B CG  1 
ATOM   9269  N  ND1 . HIS B 1 399 ? 225.493 223.626 214.913 1.00 69.09  ? 399 HIS B ND1 1 
ATOM   9270  C  CD2 . HIS B 1 399 ? 224.964 222.453 216.677 1.00 69.09  ? 399 HIS B CD2 1 
ATOM   9271  C  CE1 . HIS B 1 399 ? 224.971 224.460 215.793 1.00 69.09  ? 399 HIS B CE1 1 
ATOM   9272  N  NE2 . HIS B 1 399 ? 224.642 223.774 216.872 1.00 69.09  ? 399 HIS B NE2 1 
ATOM   9273  N  N   . ASN B 1 400 ? 226.257 218.874 212.715 1.00 73.02  ? 400 ASN B N   1 
ATOM   9274  C  CA  . ASN B 1 400 ? 227.018 217.744 212.202 1.00 73.02  ? 400 ASN B CA  1 
ATOM   9275  C  C   . ASN B 1 400 ? 226.888 217.562 210.699 1.00 73.02  ? 400 ASN B C   1 
ATOM   9276  O  O   . ASN B 1 400 ? 227.684 216.820 210.113 1.00 73.02  ? 400 ASN B O   1 
ATOM   9277  C  CB  . ASN B 1 400 ? 226.578 216.460 212.905 1.00 73.02  ? 400 ASN B CB  1 
ATOM   9278  C  CG  . ASN B 1 400 ? 226.887 216.474 214.387 1.00 73.02  ? 400 ASN B CG  1 
ATOM   9279  O  OD1 . ASN B 1 400 ? 227.156 217.526 214.966 1.00 73.02  ? 400 ASN B OD1 1 
ATOM   9280  N  ND2 . ASN B 1 400 ? 226.850 215.302 215.011 1.00 73.02  ? 400 ASN B ND2 1 
ATOM   9281  N  N   . TYR B 1 401 ? 225.905 218.194 210.066 1.00 71.66  ? 401 TYR B N   1 
ATOM   9282  C  CA  . TYR B 1 401 ? 225.769 218.141 208.615 1.00 71.66  ? 401 TYR B CA  1 
ATOM   9283  C  C   . TYR B 1 401 ? 226.432 219.328 207.924 1.00 71.66  ? 401 TYR B C   1 
ATOM   9284  O  O   . TYR B 1 401 ? 227.178 219.156 206.952 1.00 71.66  ? 401 TYR B O   1 
ATOM   9285  C  CB  . TYR B 1 401 ? 224.283 218.072 208.254 1.00 71.66  ? 401 TYR B CB  1 
ATOM   9286  C  CG  . TYR B 1 401 ? 223.981 218.206 206.789 1.00 71.66  ? 401 TYR B CG  1 
ATOM   9287  C  CD1 . TYR B 1 401 ? 223.641 219.430 206.244 1.00 71.66  ? 401 TYR B CD1 1 
ATOM   9288  C  CD2 . TYR B 1 401 ? 224.015 217.104 205.957 1.00 71.66  ? 401 TYR B CD2 1 
ATOM   9289  C  CE1 . TYR B 1 401 ? 223.354 219.555 204.911 1.00 71.66  ? 401 TYR B CE1 1 
ATOM   9290  C  CE2 . TYR B 1 401 ? 223.731 217.218 204.619 1.00 71.66  ? 401 TYR B CE2 1 
ATOM   9291  C  CZ  . TYR B 1 401 ? 223.400 218.447 204.100 1.00 71.66  ? 401 TYR B CZ  1 
ATOM   9292  O  OH  . TYR B 1 401 ? 223.114 218.568 202.759 1.00 71.66  ? 401 TYR B OH  1 
ATOM   9293  N  N   . LEU B 1 402 ? 226.185 220.541 208.422 1.00 70.15  ? 402 LEU B N   1 
ATOM   9294  C  CA  . LEU B 1 402 ? 226.752 221.724 207.797 1.00 70.15  ? 402 LEU B CA  1 
ATOM   9295  C  C   . LEU B 1 402 ? 228.256 221.799 208.011 1.00 70.15  ? 402 LEU B C   1 
ATOM   9296  O  O   . LEU B 1 402 ? 228.971 222.317 207.148 1.00 70.15  ? 402 LEU B O   1 
ATOM   9297  C  CB  . LEU B 1 402 ? 226.060 222.977 208.333 1.00 70.15  ? 402 LEU B CB  1 
ATOM   9298  C  CG  . LEU B 1 402 ? 226.262 224.305 207.597 1.00 70.15  ? 402 LEU B CG  1 
ATOM   9299  C  CD1 . LEU B 1 402 ? 225.038 225.181 207.773 1.00 70.15  ? 402 LEU B CD1 1 
ATOM   9300  C  CD2 . LEU B 1 402 ? 227.494 225.045 208.069 1.00 70.15  ? 402 LEU B CD2 1 
ATOM   9301  N  N   . ASP B 1 403 ? 228.767 221.295 209.140 1.00 72.24  ? 403 ASP B N   1 
ATOM   9302  C  CA  . ASP B 1 403 ? 230.216 221.272 209.299 1.00 72.24  ? 403 ASP B CA  1 
ATOM   9303  C  C   . ASP B 1 403 ? 230.854 220.349 208.272 1.00 72.24  ? 403 ASP B C   1 
ATOM   9304  O  O   . ASP B 1 403 ? 231.913 220.661 207.719 1.00 72.24  ? 403 ASP B O   1 
ATOM   9305  C  CB  . ASP B 1 403 ? 230.604 220.866 210.724 1.00 72.24  ? 403 ASP B CB  1 
ATOM   9306  C  CG  . ASP B 1 403 ? 230.199 219.446 211.075 1.00 72.24  ? 403 ASP B CG  1 
ATOM   9307  O  OD1 . ASP B 1 403 ? 229.666 218.726 210.208 1.00 72.24  ? 403 ASP B OD1 1 
ATOM   9308  O  OD2 . ASP B 1 403 ? 230.420 219.043 212.236 1.00 72.24  ? 403 ASP B OD2 1 
ATOM   9309  N  N   . ASP B 1 404 ? 230.215 219.209 207.997 1.00 74.66  ? 404 ASP B N   1 
ATOM   9310  C  CA  . ASP B 1 404 ? 230.704 218.312 206.957 1.00 74.66  ? 404 ASP B CA  1 
ATOM   9311  C  C   . ASP B 1 404 ? 230.646 218.963 205.582 1.00 74.66  ? 404 ASP B C   1 
ATOM   9312  O  O   . ASP B 1 404 ? 231.565 218.787 204.776 1.00 74.66  ? 404 ASP B O   1 
ATOM   9313  C  CB  . ASP B 1 404 ? 229.900 217.013 206.963 1.00 74.66  ? 404 ASP B CB  1 
ATOM   9314  C  CG  . ASP B 1 404 ? 230.600 215.892 206.223 1.00 74.66  ? 404 ASP B CG  1 
ATOM   9315  O  OD1 . ASP B 1 404 ? 231.845 215.926 206.130 1.00 74.66  ? 404 ASP B OD1 1 
ATOM   9316  O  OD2 . ASP B 1 404 ? 229.906 214.976 205.734 1.00 74.66  ? 404 ASP B OD2 1 
ATOM   9317  N  N   . LEU B 1 405 ? 229.575 219.702 205.290 1.00 69.12  ? 405 LEU B N   1 
ATOM   9318  C  CA  . LEU B 1 405 ? 229.504 220.400 204.009 1.00 69.12  ? 405 LEU B CA  1 
ATOM   9319  C  C   . LEU B 1 405 ? 230.609 221.440 203.884 1.00 69.12  ? 405 LEU B C   1 
ATOM   9320  O  O   . LEU B 1 405 ? 231.275 221.531 202.847 1.00 69.12  ? 405 LEU B O   1 
ATOM   9321  C  CB  . LEU B 1 405 ? 228.138 221.058 203.827 1.00 69.12  ? 405 LEU B CB  1 
ATOM   9322  C  CG  . LEU B 1 405 ? 227.003 220.163 203.337 1.00 69.12  ? 405 LEU B CG  1 
ATOM   9323  C  CD1 . LEU B 1 405 ? 225.801 221.012 202.965 1.00 69.12  ? 405 LEU B CD1 1 
ATOM   9324  C  CD2 . LEU B 1 405 ? 227.455 219.321 202.157 1.00 69.12  ? 405 LEU B CD2 1 
ATOM   9325  N  N   . VAL B 1 406 ? 230.831 222.231 204.936 1.00 70.55  ? 406 VAL B N   1 
ATOM   9326  C  CA  . VAL B 1 406 ? 231.804 223.313 204.851 1.00 70.55  ? 406 VAL B CA  1 
ATOM   9327  C  C   . VAL B 1 406 ? 233.234 222.798 204.946 1.00 70.55  ? 406 VAL B C   1 
ATOM   9328  O  O   . VAL B 1 406 ? 234.166 223.491 204.524 1.00 70.55  ? 406 VAL B O   1 
ATOM   9329  C  CB  . VAL B 1 406 ? 231.529 224.372 205.935 1.00 70.55  ? 406 VAL B CB  1 
ATOM   9330  C  CG1 . VAL B 1 406 ? 231.990 223.881 207.298 1.00 70.55  ? 406 VAL B CG1 1 
ATOM   9331  C  CG2 . VAL B 1 406 ? 232.191 225.694 205.575 1.00 70.55  ? 406 VAL B CG2 1 
ATOM   9332  N  N   . ASP B 1 407 ? 233.437 221.594 205.484 1.00 72.97  ? 407 ASP B N   1 
ATOM   9333  C  CA  . ASP B 1 407 ? 234.779 221.030 205.543 1.00 72.97  ? 407 ASP B CA  1 
ATOM   9334  C  C   . ASP B 1 407 ? 235.293 220.686 204.151 1.00 72.97  ? 407 ASP B C   1 
ATOM   9335  O  O   . ASP B 1 407 ? 236.489 220.826 203.870 1.00 72.97  ? 407 ASP B O   1 
ATOM   9336  C  CB  . ASP B 1 407 ? 234.786 219.793 206.440 1.00 72.97  ? 407 ASP B CB  1 
ATOM   9337  C  CG  . ASP B 1 407 ? 236.177 219.429 206.923 1.00 72.97  ? 407 ASP B CG  1 
ATOM   9338  O  OD1 . ASP B 1 407 ? 237.135 220.158 206.590 1.00 72.97  ? 407 ASP B OD1 1 
ATOM   9339  O  OD2 . ASP B 1 407 ? 236.312 218.414 207.638 1.00 72.97  ? 407 ASP B OD2 1 
ATOM   9340  N  N   . LYS B 1 408 ? 234.404 220.248 203.264 1.00 69.42  ? 408 LYS B N   1 
ATOM   9341  C  CA  . LYS B 1 408 ? 234.766 219.874 201.900 1.00 69.42  ? 408 LYS B CA  1 
ATOM   9342  C  C   . LYS B 1 408 ? 235.050 221.061 201.023 1.00 69.42  ? 408 LYS B C   1 
ATOM   9343  O  O   . LYS B 1 408 ? 235.108 220.884 199.801 1.00 69.42  ? 408 LYS B O   1 
ATOM   9344  C  CB  . LYS B 1 408 ? 233.656 219.027 201.278 1.00 69.42  ? 408 LYS B CB  1 
ATOM   9345  C  CG  . LYS B 1 408 ? 233.340 217.739 202.030 1.00 69.42  ? 408 LYS B CG  1 
ATOM   9346  C  CD  . LYS B 1 408 ? 234.423 216.681 201.845 1.00 69.42  ? 408 LYS B CD  1 
ATOM   9347  C  CE  . LYS B 1 408 ? 235.364 216.611 203.041 1.00 69.42  ? 408 LYS B CE  1 
ATOM   9348  N  NZ  . LYS B 1 408 ? 236.354 215.507 202.904 1.00 69.42  ? 408 LYS B NZ  1 
ATOM   9349  N  N   . ALA B 1 409 ? 235.191 222.247 201.612 1.00 68.38  ? 409 ALA B N   1 
ATOM   9350  C  CA  . ALA B 1 409 ? 235.522 223.506 200.953 1.00 68.38  ? 409 ALA B CA  1 
ATOM   9351  C  C   . ALA B 1 409 ? 234.408 224.013 200.047 1.00 68.38  ? 409 ALA B C   1 
ATOM   9352  O  O   . ALA B 1 409 ? 234.534 225.114 199.497 1.00 68.38  ? 409 ALA B O   1 
ATOM   9353  C  CB  . ALA B 1 409 ? 236.823 223.420 200.141 1.00 68.38  ? 409 ALA B CB  1 
ATOM   9354  N  N   . VAL B 1 410 ? 233.325 223.264 199.873 1.00 63.39  ? 410 VAL B N   1 
ATOM   9355  C  CA  . VAL B 1 410 ? 232.185 223.747 199.104 1.00 63.39  ? 410 VAL B CA  1 
ATOM   9356  C  C   . VAL B 1 410 ? 231.410 224.719 199.982 1.00 63.39  ? 410 VAL B C   1 
ATOM   9357  O  O   . VAL B 1 410 ? 231.281 224.514 201.192 1.00 63.39  ? 410 VAL B O   1 
ATOM   9358  C  CB  . VAL B 1 410 ? 231.303 222.586 198.616 1.00 63.39  ? 410 VAL B CB  1 
ATOM   9359  C  CG1 . VAL B 1 410 ? 230.547 221.939 199.763 1.00 63.39  ? 410 VAL B CG1 1 
ATOM   9360  C  CG2 . VAL B 1 410 ? 230.340 223.062 197.542 1.00 63.39  ? 410 VAL B CG2 1 
ATOM   9361  N  N   . SER B 1 411 ? 230.924 225.793 199.385 1.00 62.81  ? 411 SER B N   1 
ATOM   9362  C  CA  . SER B 1 411 ? 230.292 226.837 200.171 1.00 62.81  ? 411 SER B CA  1 
ATOM   9363  C  C   . SER B 1 411 ? 228.781 226.764 200.034 1.00 62.81  ? 411 SER B C   1 
ATOM   9364  O  O   . SER B 1 411 ? 228.229 227.160 199.001 1.00 62.81  ? 411 SER B O   1 
ATOM   9365  C  CB  . SER B 1 411 ? 230.791 228.208 199.735 1.00 62.81  ? 411 SER B CB  1 
ATOM   9366  O  OG  . SER B 1 411 ? 230.239 228.564 198.482 1.00 62.81  ? 411 SER B OG  1 
ATOM   9367  N  N   . PRO B 1 412 ? 228.081 226.291 201.055 1.00 60.72  ? 412 PRO B N   1 
ATOM   9368  C  CA  . PRO B 1 412 ? 226.627 226.176 200.970 1.00 60.72  ? 412 PRO B CA  1 
ATOM   9369  C  C   . PRO B 1 412 ? 225.977 227.540 201.115 1.00 60.72  ? 412 PRO B C   1 
ATOM   9370  O  O   . PRO B 1 412 ? 226.625 228.544 201.399 1.00 60.72  ? 412 PRO B O   1 
ATOM   9371  C  CB  . PRO B 1 412 ? 226.277 225.267 202.147 1.00 60.72  ? 412 PRO B CB  1 
ATOM   9372  C  CG  . PRO B 1 412 ? 227.346 225.532 203.144 1.00 60.72  ? 412 PRO B CG  1 
ATOM   9373  C  CD  . PRO B 1 412 ? 228.589 225.921 202.387 1.00 60.72  ? 412 PRO B CD  1 
ATOM   9374  N  N   . VAL B 1 413 ? 224.671 227.558 200.904 1.00 60.30  ? 413 VAL B N   1 
ATOM   9375  C  CA  . VAL B 1 413 ? 223.865 228.743 201.113 1.00 60.30  ? 413 VAL B CA  1 
ATOM   9376  C  C   . VAL B 1 413 ? 222.861 228.388 202.197 1.00 60.30  ? 413 VAL B C   1 
ATOM   9377  O  O   . VAL B 1 413 ? 222.106 227.413 202.068 1.00 60.30  ? 413 VAL B O   1 
ATOM   9378  C  CB  . VAL B 1 413 ? 223.173 229.207 199.829 1.00 60.30  ? 413 VAL B CB  1 
ATOM   9379  C  CG1 . VAL B 1 413 ? 222.535 230.551 200.052 1.00 60.30  ? 413 VAL B CG1 1 
ATOM   9380  C  CG2 . VAL B 1 413 ? 224.179 229.287 198.705 1.00 60.30  ? 413 VAL B CG2 1 
ATOM   9381  N  N   . VAL B 1 414 ? 222.865 229.168 203.271 1.00 62.49  ? 414 VAL B N   1 
ATOM   9382  C  CA  . VAL B 1 414 ? 222.083 228.895 204.466 1.00 62.49  ? 414 VAL B CA  1 
ATOM   9383  C  C   . VAL B 1 414 ? 220.900 229.848 204.467 1.00 62.49  ? 414 VAL B C   1 
ATOM   9384  O  O   . VAL B 1 414 ? 221.073 231.072 204.417 1.00 62.49  ? 414 VAL B O   1 
ATOM   9385  C  CB  . VAL B 1 414 ? 222.928 229.052 205.733 1.00 62.49  ? 414 VAL B CB  1 
ATOM   9386  C  CG1 . VAL B 1 414 ? 222.168 228.557 206.941 1.00 62.49  ? 414 VAL B CG1 1 
ATOM   9387  C  CG2 . VAL B 1 414 ? 224.243 228.309 205.583 1.00 62.49  ? 414 VAL B CG2 1 
ATOM   9388  N  N   . TYR B 1 415 ? 219.699 229.286 204.518 1.00 66.22  ? 415 TYR B N   1 
ATOM   9389  C  CA  . TYR B 1 415 ? 218.471 230.059 204.573 1.00 66.22  ? 415 TYR B CA  1 
ATOM   9390  C  C   . TYR B 1 415 ? 217.939 230.014 205.996 1.00 66.22  ? 415 TYR B C   1 
ATOM   9391  O  O   . TYR B 1 415 ? 217.543 228.947 206.475 1.00 66.22  ? 415 TYR B O   1 
ATOM   9392  C  CB  . TYR B 1 415 ? 217.434 229.490 203.610 1.00 66.22  ? 415 TYR B CB  1 
ATOM   9393  C  CG  . TYR B 1 415 ? 217.614 229.917 202.180 1.00 66.22  ? 415 TYR B CG  1 
ATOM   9394  C  CD1 . TYR B 1 415 ? 218.876 230.091 201.642 1.00 66.22  ? 415 TYR B CD1 1 
ATOM   9395  C  CD2 . TYR B 1 415 ? 216.520 230.146 201.368 1.00 66.22  ? 415 TYR B CD2 1 
ATOM   9396  C  CE1 . TYR B 1 415 ? 219.040 230.477 200.338 1.00 66.22  ? 415 TYR B CE1 1 
ATOM   9397  C  CE2 . TYR B 1 415 ? 216.675 230.533 200.065 1.00 66.22  ? 415 TYR B CE2 1 
ATOM   9398  C  CZ  . TYR B 1 415 ? 217.937 230.699 199.556 1.00 66.22  ? 415 TYR B CZ  1 
ATOM   9399  O  OH  . TYR B 1 415 ? 218.099 231.093 198.256 1.00 66.22  ? 415 TYR B OH  1 
ATOM   9400  N  N   . LEU B 1 416 ? 217.935 231.158 206.670 1.00 71.48  ? 416 LEU B N   1 
ATOM   9401  C  CA  . LEU B 1 416 ? 217.336 231.271 207.990 1.00 71.48  ? 416 LEU B CA  1 
ATOM   9402  C  C   . LEU B 1 416 ? 215.909 231.763 207.824 1.00 71.48  ? 416 LEU B C   1 
ATOM   9403  O  O   . LEU B 1 416 ? 215.689 232.890 207.372 1.00 71.48  ? 416 LEU B O   1 
ATOM   9404  C  CB  . LEU B 1 416 ? 218.143 232.213 208.881 1.00 71.48  ? 416 LEU B CB  1 
ATOM   9405  C  CG  . LEU B 1 416 ? 219.174 231.593 209.827 1.00 71.48  ? 416 LEU B CG  1 
ATOM   9406  C  CD1 . LEU B 1 416 ? 218.471 230.888 210.972 1.00 71.48  ? 416 LEU B CD1 1 
ATOM   9407  C  CD2 . LEU B 1 416 ? 220.079 230.620 209.091 1.00 71.48  ? 416 LEU B CD2 1 
ATOM   9408  N  N   . ILE B 1 417 ? 214.947 230.919 208.182 1.00 66.85  ? 417 ILE B N   1 
ATOM   9409  C  CA  . ILE B 1 417 ? 213.532 231.214 208.012 1.00 66.85  ? 417 ILE B CA  1 
ATOM   9410  C  C   . ILE B 1 417 ? 212.911 231.370 209.388 1.00 66.85  ? 417 ILE B C   1 
ATOM   9411  O  O   . ILE B 1 417 ? 213.100 230.517 210.263 1.00 66.85  ? 417 ILE B O   1 
ATOM   9412  C  CB  . ILE B 1 417 ? 212.815 230.116 207.210 1.00 66.85  ? 417 ILE B CB  1 
ATOM   9413  C  CG1 . ILE B 1 417 ? 213.481 229.915 205.848 1.00 66.85  ? 417 ILE B CG1 1 
ATOM   9414  C  CG2 . ILE B 1 417 ? 211.351 230.464 207.027 1.00 66.85  ? 417 ILE B CG2 1 
ATOM   9415  C  CD1 . ILE B 1 417 ? 214.428 228.737 205.795 1.00 66.85  ? 417 ILE B CD1 1 
ATOM   9416  N  N   . GLY B 1 418 ? 212.176 232.459 209.583 1.00 68.81  ? 418 GLY B N   1 
ATOM   9417  C  CA  . GLY B 1 418 ? 211.448 232.661 210.814 1.00 68.81  ? 418 GLY B CA  1 
ATOM   9418  C  C   . GLY B 1 418 ? 209.991 232.963 210.556 1.00 68.81  ? 418 GLY B C   1 
ATOM   9419  O  O   . GLY B 1 418 ? 209.653 233.990 209.962 1.00 68.81  ? 418 GLY B O   1 
ATOM   9420  N  N   . VAL B 1 419 ? 209.117 232.056 210.984 1.00 70.68  ? 419 VAL B N   1 
ATOM   9421  C  CA  . VAL B 1 419 ? 207.691 232.292 210.853 1.00 70.68  ? 419 VAL B CA  1 
ATOM   9422  C  C   . VAL B 1 419 ? 207.257 233.316 211.893 1.00 70.68  ? 419 VAL B C   1 
ATOM   9423  O  O   . VAL B 1 419 ? 207.683 233.279 213.053 1.00 70.68  ? 419 VAL B O   1 
ATOM   9424  C  CB  . VAL B 1 419 ? 206.911 230.972 210.988 1.00 70.68  ? 419 VAL B CB  1 
ATOM   9425  C  CG1 . VAL B 1 419 ? 207.284 230.261 212.272 1.00 70.68  ? 419 VAL B CG1 1 
ATOM   9426  C  CG2 . VAL B 1 419 ? 205.419 231.225 210.925 1.00 70.68  ? 419 VAL B CG2 1 
ATOM   9427  N  N   . ASP B 1 420 ? 206.432 234.261 211.467 1.00 75.88  ? 420 ASP B N   1 
ATOM   9428  C  CA  . ASP B 1 420 ? 205.953 235.326 212.329 1.00 75.88  ? 420 ASP B CA  1 
ATOM   9429  C  C   . ASP B 1 420 ? 204.464 235.145 212.590 1.00 75.88  ? 420 ASP B C   1 
ATOM   9430  O  O   . ASP B 1 420 ? 203.799 234.307 211.975 1.00 75.88  ? 420 ASP B O   1 
ATOM   9431  C  CB  . ASP B 1 420 ? 206.221 236.694 211.701 1.00 75.88  ? 420 ASP B CB  1 
ATOM   9432  C  CG  . ASP B 1 420 ? 207.622 236.811 211.158 1.00 75.88  ? 420 ASP B CG  1 
ATOM   9433  O  OD1 . ASP B 1 420 ? 208.520 236.129 211.693 1.00 75.88  ? 420 ASP B OD1 1 
ATOM   9434  O  OD2 . ASP B 1 420 ? 207.827 237.577 210.195 1.00 75.88  ? 420 ASP B OD2 1 
ATOM   9435  N  N   . HIS B 1 421 ? 203.951 235.948 213.523 1.00 82.08  ? 421 HIS B N   1 
ATOM   9436  C  CA  . HIS B 1 421 ? 202.521 235.987 213.841 1.00 82.08  ? 421 HIS B CA  1 
ATOM   9437  C  C   . HIS B 1 421 ? 202.001 234.621 214.284 1.00 82.08  ? 421 HIS B C   1 
ATOM   9438  O  O   . HIS B 1 421 ? 200.956 234.155 213.827 1.00 82.08  ? 421 HIS B O   1 
ATOM   9439  C  CB  . HIS B 1 421 ? 201.709 236.520 212.659 1.00 82.08  ? 421 HIS B CB  1 
ATOM   9440  C  CG  . HIS B 1 421 ? 200.386 237.099 213.047 1.00 82.08  ? 421 HIS B CG  1 
ATOM   9441  N  ND1 . HIS B 1 421 ? 199.328 237.192 212.169 1.00 82.08  ? 421 HIS B ND1 1 
ATOM   9442  C  CD2 . HIS B 1 421 ? 199.948 237.614 214.220 1.00 82.08  ? 421 HIS B CD2 1 
ATOM   9443  C  CE1 . HIS B 1 421 ? 198.295 237.741 212.784 1.00 82.08  ? 421 HIS B CE1 1 
ATOM   9444  N  NE2 . HIS B 1 421 ? 198.645 238.006 214.030 1.00 82.08  ? 421 HIS B NE2 1 
ATOM   9445  N  N   . ILE B 1 422 ? 202.744 233.966 215.182 1.00 79.19  ? 422 ILE B N   1 
ATOM   9446  C  CA  . ILE B 1 422 ? 202.298 232.701 215.759 1.00 79.19  ? 422 ILE B CA  1 
ATOM   9447  C  C   . ILE B 1 422 ? 201.687 232.887 217.141 1.00 79.19  ? 422 ILE B C   1 
ATOM   9448  O  O   . ILE B 1 422 ? 200.902 232.030 217.586 1.00 79.19  ? 422 ILE B O   1 
ATOM   9449  C  CB  . ILE B 1 422 ? 203.471 231.701 215.813 1.00 79.19  ? 422 ILE B CB  1 
ATOM   9450  C  CG1 . ILE B 1 422 ? 202.955 230.265 215.918 1.00 79.19  ? 422 ILE B CG1 1 
ATOM   9451  C  CG2 . ILE B 1 422 ? 204.399 232.023 216.968 1.00 79.19  ? 422 ILE B CG2 1 
ATOM   9452  C  CD1 . ILE B 1 422 ? 202.230 229.785 214.680 1.00 79.19  ? 422 ILE B CD1 1 
ATOM   9453  N  N   . GLN B 1 423 ? 201.997 233.992 217.824 1.00 82.00  ? 423 GLN B N   1 
ATOM   9454  C  CA  . GLN B 1 423 ? 201.451 234.227 219.155 1.00 82.00  ? 423 GLN B CA  1 
ATOM   9455  C  C   . GLN B 1 423 ? 199.936 234.367 219.129 1.00 82.00  ? 423 GLN B C   1 
ATOM   9456  O  O   . GLN B 1 423 ? 199.276 234.052 220.122 1.00 82.00  ? 423 GLN B O   1 
ATOM   9457  C  CB  . GLN B 1 423 ? 202.087 235.471 219.770 1.00 82.00  ? 423 GLN B CB  1 
ATOM   9458  C  CG  . GLN B 1 423 ? 201.794 235.646 221.249 1.00 82.00  ? 423 GLN B CG  1 
ATOM   9459  C  CD  . GLN B 1 423 ? 202.230 234.452 222.074 1.00 82.00  ? 423 GLN B CD  1 
ATOM   9460  O  OE1 . GLN B 1 423 ? 203.306 233.894 221.859 1.00 82.00  ? 423 GLN B OE1 1 
ATOM   9461  N  NE2 . GLN B 1 423 ? 201.394 234.052 223.024 1.00 82.00  ? 423 GLN B NE2 1 
ATOM   9462  N  N   . ASP B 1 424 ? 199.368 234.828 218.012 1.00 81.70  ? 424 ASP B N   1 
ATOM   9463  C  CA  . ASP B 1 424 ? 197.916 234.949 217.925 1.00 81.70  ? 424 ASP B CA  1 
ATOM   9464  C  C   . ASP B 1 424 ? 197.243 233.588 218.071 1.00 81.70  ? 424 ASP B C   1 
ATOM   9465  O  O   . ASP B 1 424 ? 196.295 233.430 218.850 1.00 81.70  ? 424 ASP B O   1 
ATOM   9466  C  CB  . ASP B 1 424 ? 197.520 235.620 216.609 1.00 81.70  ? 424 ASP B CB  1 
ATOM   9467  C  CG  . ASP B 1 424 ? 197.959 234.831 215.393 1.00 81.70  ? 424 ASP B CG  1 
ATOM   9468  O  OD1 . ASP B 1 424 ? 198.775 233.899 215.549 1.00 81.70  ? 424 ASP B OD1 1 
ATOM   9469  O  OD2 . ASP B 1 424 ? 197.486 235.141 214.279 1.00 81.70  ? 424 ASP B OD2 1 
ATOM   9470  N  N   . VAL B 1 425 ? 197.737 232.585 217.343 1.00 76.23  ? 425 VAL B N   1 
ATOM   9471  C  CA  . VAL B 1 425 ? 197.214 231.234 217.497 1.00 76.23  ? 425 VAL B CA  1 
ATOM   9472  C  C   . VAL B 1 425 ? 197.558 230.689 218.875 1.00 76.23  ? 425 VAL B C   1 
ATOM   9473  O  O   . VAL B 1 425 ? 196.721 230.054 219.530 1.00 76.23  ? 425 VAL B O   1 
ATOM   9474  C  CB  . VAL B 1 425 ? 197.746 230.321 216.379 1.00 76.23  ? 425 VAL B CB  1 
ATOM   9475  C  CG1 . VAL B 1 425 ? 197.117 228.948 216.468 1.00 76.23  ? 425 VAL B CG1 1 
ATOM   9476  C  CG2 . VAL B 1 425 ? 197.483 230.938 215.024 1.00 76.23  ? 425 VAL B CG2 1 
ATOM   9477  N  N   . ILE B 1 426 ? 198.784 230.952 219.350 1.00 78.84  ? 426 ILE B N   1 
ATOM   9478  C  CA  . ILE B 1 426 ? 199.212 230.448 220.657 1.00 78.84  ? 426 ILE B CA  1 
ATOM   9479  C  C   . ILE B 1 426 ? 198.259 230.902 221.749 1.00 78.84  ? 426 ILE B C   1 
ATOM   9480  O  O   . ILE B 1 426 ? 197.936 230.137 222.665 1.00 78.84  ? 426 ILE B O   1 
ATOM   9481  C  CB  . ILE B 1 426 ? 200.655 230.900 220.968 1.00 78.84  ? 426 ILE B CB  1 
ATOM   9482  C  CG1 . ILE B 1 426 ? 201.655 230.227 220.031 1.00 78.84  ? 426 ILE B CG1 1 
ATOM   9483  C  CG2 . ILE B 1 426 ? 201.011 230.590 222.412 1.00 78.84  ? 426 ILE B CG2 1 
ATOM   9484  C  CD1 . ILE B 1 426 ? 203.062 230.769 220.152 1.00 78.84  ? 426 ILE B CD1 1 
ATOM   9485  N  N   . ASP B 1 427 ? 197.795 232.148 221.673 1.00 81.51  ? 427 ASP B N   1 
ATOM   9486  C  CA  . ASP B 1 427 ? 196.883 232.678 222.678 1.00 81.51  ? 427 ASP B CA  1 
ATOM   9487  C  C   . ASP B 1 427 ? 195.456 232.204 222.436 1.00 81.51  ? 427 ASP B C   1 
ATOM   9488  O  O   . ASP B 1 427 ? 194.827 231.621 223.325 1.00 81.51  ? 427 ASP B O   1 
ATOM   9489  C  CB  . ASP B 1 427 ? 196.946 234.208 222.689 1.00 81.51  ? 427 ASP B CB  1 
ATOM   9490  C  CG  . ASP B 1 427 ? 198.254 234.734 223.246 1.00 81.51  ? 427 ASP B CG  1 
ATOM   9491  O  OD1 . ASP B 1 427 ? 199.060 233.921 223.746 1.00 81.51  ? 427 ASP B OD1 1 
ATOM   9492  O  OD2 . ASP B 1 427 ? 198.477 235.961 223.184 1.00 81.51  ? 427 ASP B OD2 1 
ATOM   9493  N  N   . SER B 1 428 ? 194.925 232.445 221.235 1.00 72.64  ? 428 SER B N   1 
ATOM   9494  C  CA  . SER B 1 428 ? 193.514 232.180 220.995 1.00 72.64  ? 428 SER B CA  1 
ATOM   9495  C  C   . SER B 1 428 ? 193.163 230.704 221.111 1.00 72.64  ? 428 SER B C   1 
ATOM   9496  O  O   . SER B 1 428 ? 192.098 230.381 221.647 1.00 72.64  ? 428 SER B O   1 
ATOM   9497  C  CB  . SER B 1 428 ? 193.106 232.709 219.623 1.00 72.64  ? 428 SER B CB  1 
ATOM   9498  O  OG  . SER B 1 428 ? 193.797 232.026 218.595 1.00 72.64  ? 428 SER B OG  1 
ATOM   9499  N  N   . LEU B 1 429 ? 194.016 229.797 220.628 1.00 70.09  ? 429 LEU B N   1 
ATOM   9500  C  CA  . LEU B 1 429 ? 193.689 228.378 220.675 1.00 70.09  ? 429 LEU B CA  1 
ATOM   9501  C  C   . LEU B 1 429 ? 194.626 227.542 221.531 1.00 70.09  ? 429 LEU B C   1 
ATOM   9502  O  O   . LEU B 1 429 ? 194.311 226.374 221.784 1.00 70.09  ? 429 LEU B O   1 
ATOM   9503  C  CB  . LEU B 1 429 ? 193.648 227.780 219.261 1.00 70.09  ? 429 LEU B CB  1 
ATOM   9504  C  CG  . LEU B 1 429 ? 192.284 227.785 218.570 1.00 70.09  ? 429 LEU B CG  1 
ATOM   9505  C  CD1 . LEU B 1 429 ? 191.289 226.978 219.379 1.00 70.09  ? 429 LEU B CD1 1 
ATOM   9506  C  CD2 . LEU B 1 429 ? 191.774 229.195 218.342 1.00 70.09  ? 429 LEU B CD2 1 
ATOM   9507  N  N   . GLY B 1 430 ? 195.749 228.081 221.983 1.00 75.59  ? 430 GLY B N   1 
ATOM   9508  C  CA  . GLY B 1 430 ? 196.605 227.370 222.911 1.00 75.59  ? 430 GLY B CA  1 
ATOM   9509  C  C   . GLY B 1 430 ? 197.784 226.702 222.231 1.00 75.59  ? 430 GLY B C   1 
ATOM   9510  O  O   . GLY B 1 430 ? 197.911 226.658 221.002 1.00 75.59  ? 430 GLY B O   1 
ATOM   9511  N  N   . TYR B 1 431 ? 198.661 226.161 223.081 1.00 74.36  ? 431 TYR B N   1 
ATOM   9512  C  CA  . TYR B 1 431 ? 199.882 225.531 222.593 1.00 74.36  ? 431 TYR B CA  1 
ATOM   9513  C  C   . TYR B 1 431 ? 199.593 224.258 221.813 1.00 74.36  ? 431 TYR B C   1 
ATOM   9514  O  O   . TYR B 1 431 ? 200.332 223.930 220.879 1.00 74.36  ? 431 TYR B O   1 
ATOM   9515  C  CB  . TYR B 1 431 ? 200.817 225.235 223.760 1.00 74.36  ? 431 TYR B CB  1 
ATOM   9516  C  CG  . TYR B 1 431 ? 201.487 226.466 224.311 1.00 74.36  ? 431 TYR B CG  1 
ATOM   9517  C  CD1 . TYR B 1 431 ? 202.613 226.996 223.701 1.00 74.36  ? 431 TYR B CD1 1 
ATOM   9518  C  CD2 . TYR B 1 431 ? 200.990 227.104 225.438 1.00 74.36  ? 431 TYR B CD2 1 
ATOM   9519  C  CE1 . TYR B 1 431 ? 203.230 228.125 224.200 1.00 74.36  ? 431 TYR B CE1 1 
ATOM   9520  C  CE2 . TYR B 1 431 ? 201.600 228.234 225.946 1.00 74.36  ? 431 TYR B CE2 1 
ATOM   9521  C  CZ  . TYR B 1 431 ? 202.719 228.741 225.323 1.00 74.36  ? 431 TYR B CZ  1 
ATOM   9522  O  OH  . TYR B 1 431 ? 203.331 229.867 225.824 1.00 74.36  ? 431 TYR B OH  1 
ATOM   9523  N  N   . ALA B 1 432 ? 198.524 223.542 222.164 1.00 69.92  ? 432 ALA B N   1 
ATOM   9524  C  CA  . ALA B 1 432 ? 198.206 222.303 221.465 1.00 69.92  ? 432 ALA B CA  1 
ATOM   9525  C  C   . ALA B 1 432 ? 197.951 222.560 219.987 1.00 69.92  ? 432 ALA B C   1 
ATOM   9526  O  O   . ALA B 1 432 ? 198.421 221.811 219.124 1.00 69.92  ? 432 ALA B O   1 
ATOM   9527  C  CB  . ALA B 1 432 ? 196.997 221.629 222.113 1.00 69.92  ? 432 ALA B CB  1 
ATOM   9528  N  N   . TRP B 1 433 ? 197.213 223.621 219.673 1.00 65.84  ? 433 TRP B N   1 
ATOM   9529  C  CA  . TRP B 1 433 ? 196.940 223.950 218.283 1.00 65.84  ? 433 TRP B CA  1 
ATOM   9530  C  C   . TRP B 1 433 ? 198.023 224.815 217.649 1.00 65.84  ? 433 TRP B C   1 
ATOM   9531  O  O   . TRP B 1 433 ? 198.154 224.817 216.419 1.00 65.84  ? 433 TRP B O   1 
ATOM   9532  C  CB  . TRP B 1 433 ? 195.585 224.645 218.164 1.00 65.84  ? 433 TRP B CB  1 
ATOM   9533  C  CG  . TRP B 1 433 ? 194.456 223.849 218.728 1.00 65.84  ? 433 TRP B CG  1 
ATOM   9534  C  CD1 . TRP B 1 433 ? 194.029 223.845 220.020 1.00 65.84  ? 433 TRP B CD1 1 
ATOM   9535  C  CD2 . TRP B 1 433 ? 193.593 222.957 218.020 1.00 65.84  ? 433 TRP B CD2 1 
ATOM   9536  N  NE1 . TRP B 1 433 ? 192.959 222.999 220.163 1.00 65.84  ? 433 TRP B NE1 1 
ATOM   9537  C  CE2 . TRP B 1 433 ? 192.673 222.442 218.946 1.00 65.84  ? 433 TRP B CE2 1 
ATOM   9538  C  CE3 . TRP B 1 433 ? 193.513 222.541 216.694 1.00 65.84  ? 433 TRP B CE3 1 
ATOM   9539  C  CZ2 . TRP B 1 433 ? 191.685 221.535 218.588 1.00 65.84  ? 433 TRP B CZ2 1 
ATOM   9540  C  CZ3 . TRP B 1 433 ? 192.536 221.641 216.340 1.00 65.84  ? 433 TRP B CZ3 1 
ATOM   9541  C  CH2 . TRP B 1 433 ? 191.634 221.147 217.281 1.00 65.84  ? 433 TRP B CH2 1 
ATOM   9542  N  N   . ALA B 1 434 ? 198.808 225.542 218.448 1.00 70.66  ? 434 ALA B N   1 
ATOM   9543  C  CA  . ALA B 1 434 ? 199.992 226.194 217.897 1.00 70.66  ? 434 ALA B CA  1 
ATOM   9544  C  C   . ALA B 1 434 ? 200.977 225.160 217.369 1.00 70.66  ? 434 ALA B C   1 
ATOM   9545  O  O   . ALA B 1 434 ? 201.607 225.359 216.318 1.00 70.66  ? 434 ALA B O   1 
ATOM   9546  C  CB  . ALA B 1 434 ? 200.654 227.069 218.955 1.00 70.66  ? 434 ALA B CB  1 
ATOM   9547  N  N   . ASP B 1 435 ? 201.123 224.048 218.093 1.00 71.33  ? 435 ASP B N   1 
ATOM   9548  C  CA  . ASP B 1 435 ? 201.913 222.931 217.596 1.00 71.33  ? 435 ASP B CA  1 
ATOM   9549  C  C   . ASP B 1 435 ? 201.366 222.423 216.270 1.00 71.33  ? 435 ASP B C   1 
ATOM   9550  O  O   . ASP B 1 435 ? 202.135 222.097 215.361 1.00 71.33  ? 435 ASP B O   1 
ATOM   9551  C  CB  . ASP B 1 435 ? 201.942 221.809 218.632 1.00 71.33  ? 435 ASP B CB  1 
ATOM   9552  C  CG  . ASP B 1 435 ? 202.941 220.721 218.287 1.00 71.33  ? 435 ASP B CG  1 
ATOM   9553  O  OD1 . ASP B 1 435 ? 203.866 220.993 217.493 1.00 71.33  ? 435 ASP B OD1 1 
ATOM   9554  O  OD2 . ASP B 1 435 ? 202.801 219.594 218.808 1.00 71.33  ? 435 ASP B OD2 1 
ATOM   9555  N  N   . GLN B 1 436 ? 200.039 222.362 216.133 1.00 62.65  ? 436 GLN B N   1 
ATOM   9556  C  CA  . GLN B 1 436 ? 199.448 221.927 214.872 1.00 62.65  ? 436 GLN B CA  1 
ATOM   9557  C  C   . GLN B 1 436 ? 199.754 222.902 213.744 1.00 62.65  ? 436 GLN B C   1 
ATOM   9558  O  O   . GLN B 1 436 ? 200.021 222.486 212.611 1.00 62.65  ? 436 GLN B O   1 
ATOM   9559  C  CB  . GLN B 1 436 ? 197.941 221.756 215.029 1.00 62.65  ? 436 GLN B CB  1 
ATOM   9560  C  CG  . GLN B 1 436 ? 197.570 220.691 216.019 1.00 62.65  ? 436 GLN B CG  1 
ATOM   9561  C  CD  . GLN B 1 436 ? 198.299 219.403 215.763 1.00 62.65  ? 436 GLN B CD  1 
ATOM   9562  O  OE1 . GLN B 1 436 ? 198.335 218.916 214.635 1.00 62.65  ? 436 GLN B OE1 1 
ATOM   9563  N  NE2 . GLN B 1 436 ? 198.893 218.841 216.804 1.00 62.65  ? 436 GLN B NE2 1 
ATOM   9564  N  N   . ALA B 1 437 ? 199.700 224.202 214.024 1.00 60.61  ? 437 ALA B N   1 
ATOM   9565  C  CA  . ALA B 1 437 ? 199.998 225.186 212.987 1.00 60.61  ? 437 ALA B CA  1 
ATOM   9566  C  C   . ALA B 1 437 ? 201.442 225.061 212.514 1.00 60.61  ? 437 ALA B C   1 
ATOM   9567  O  O   . ALA B 1 437 ? 201.722 225.016 211.304 1.00 60.61  ? 437 ALA B O   1 
ATOM   9568  C  CB  . ALA B 1 437 ? 199.718 226.595 213.508 1.00 60.61  ? 437 ALA B CB  1 
ATOM   9569  N  N   . LEU B 1 438 ? 202.376 224.986 213.462 1.00 59.52  ? 438 LEU B N   1 
ATOM   9570  C  CA  . LEU B 1 438 ? 203.775 224.819 213.096 1.00 59.52  ? 438 LEU B CA  1 
ATOM   9571  C  C   . LEU B 1 438 ? 204.005 223.499 212.369 1.00 59.52  ? 438 LEU B C   1 
ATOM   9572  O  O   . LEU B 1 438 ? 204.809 223.437 211.431 1.00 59.52  ? 438 LEU B O   1 
ATOM   9573  C  CB  . LEU B 1 438 ? 204.651 224.912 214.339 1.00 59.52  ? 438 LEU B CB  1 
ATOM   9574  C  CG  . LEU B 1 438 ? 206.154 224.834 214.110 1.00 59.52  ? 438 LEU B CG  1 
ATOM   9575  C  CD1 . LEU B 1 438 ? 206.872 225.890 214.925 1.00 59.52  ? 438 LEU B CD1 1 
ATOM   9576  C  CD2 . LEU B 1 438 ? 206.635 223.468 214.479 1.00 59.52  ? 438 LEU B CD2 1 
ATOM   9577  N  N   . LEU B 1 439 ? 203.298 222.439 212.772 1.00 60.64  ? 439 LEU B N   1 
ATOM   9578  C  CA  . LEU B 1 439 ? 203.421 221.146 212.104 1.00 60.64  ? 439 LEU B CA  1 
ATOM   9579  C  C   . LEU B 1 439 ? 202.917 221.208 210.668 1.00 60.64  ? 439 LEU B C   1 
ATOM   9580  O  O   . LEU B 1 439 ? 203.514 220.606 209.769 1.00 60.64  ? 439 LEU B O   1 
ATOM   9581  C  CB  . LEU B 1 439 ? 202.658 220.086 212.894 1.00 60.64  ? 439 LEU B CB  1 
ATOM   9582  C  CG  . LEU B 1 439 ? 203.117 218.642 212.725 1.00 60.64  ? 439 LEU B CG  1 
ATOM   9583  C  CD1 . LEU B 1 439 ? 204.560 218.505 213.159 1.00 60.64  ? 439 LEU B CD1 1 
ATOM   9584  C  CD2 . LEU B 1 439 ? 202.231 217.711 213.530 1.00 60.64  ? 439 LEU B CD2 1 
ATOM   9585  N  N   . GLU B 1 440 ? 201.817 221.922 210.433 1.00 58.67  ? 440 GLU B N   1 
ATOM   9586  C  CA  . GLU B 1 440 ? 201.316 222.090 209.073 1.00 58.67  ? 440 GLU B CA  1 
ATOM   9587  C  C   . GLU B 1 440 ? 202.319 222.845 208.206 1.00 58.67  ? 440 GLU B C   1 
ATOM   9588  O  O   . GLU B 1 440 ? 202.537 222.492 207.038 1.00 58.67  ? 440 GLU B O   1 
ATOM   9589  C  CB  . GLU B 1 440 ? 199.972 222.812 209.104 1.00 58.67  ? 440 GLU B CB  1 
ATOM   9590  C  CG  . GLU B 1 440 ? 199.269 222.893 207.766 1.00 58.67  ? 440 GLU B CG  1 
ATOM   9591  C  CD  . GLU B 1 440 ? 198.692 221.568 207.325 1.00 58.67  ? 440 GLU B CD  1 
ATOM   9592  O  OE1 . GLU B 1 440 ? 198.421 220.716 208.196 1.00 58.67  ? 440 GLU B OE1 1 
ATOM   9593  O  OE2 . GLU B 1 440 ? 198.506 221.378 206.105 1.00 58.67  ? 440 GLU B OE2 1 
ATOM   9594  N  N   . VAL B 1 441 ? 202.942 223.890 208.759 1.00 54.86  ? 441 VAL B N   1 
ATOM   9595  C  CA  . VAL B 1 441 ? 203.966 224.611 208.000 1.00 54.86  ? 441 VAL B CA  1 
ATOM   9596  C  C   . VAL B 1 441 ? 205.144 223.693 207.680 1.00 54.86  ? 441 VAL B C   1 
ATOM   9597  O  O   . VAL B 1 441 ? 205.685 223.708 206.562 1.00 54.86  ? 441 VAL B O   1 
ATOM   9598  C  CB  . VAL B 1 441 ? 204.415 225.865 208.769 1.00 54.86  ? 441 VAL B CB  1 
ATOM   9599  C  CG1 . VAL B 1 441 ? 205.630 226.481 208.110 1.00 54.86  ? 441 VAL B CG1 1 
ATOM   9600  C  CG2 . VAL B 1 441 ? 203.289 226.866 208.828 1.00 54.86  ? 441 VAL B CG2 1 
ATOM   9601  N  N   . VAL B 1 442 ? 205.566 222.888 208.657 1.00 57.18  ? 442 VAL B N   1 
ATOM   9602  C  CA  . VAL B 1 442 ? 206.633 221.923 208.413 1.00 57.18  ? 442 VAL B CA  1 
ATOM   9603  C  C   . VAL B 1 442 ? 206.239 220.965 207.299 1.00 57.18  ? 442 VAL B C   1 
ATOM   9604  O  O   . VAL B 1 442 ? 207.065 220.596 206.457 1.00 57.18  ? 442 VAL B O   1 
ATOM   9605  C  CB  . VAL B 1 442 ? 206.978 221.169 209.708 1.00 57.18  ? 442 VAL B CB  1 
ATOM   9606  C  CG1 . VAL B 1 442 ? 207.867 219.986 209.406 1.00 57.18  ? 442 VAL B CG1 1 
ATOM   9607  C  CG2 . VAL B 1 442 ? 207.665 222.101 210.690 1.00 57.18  ? 442 VAL B CG2 1 
ATOM   9608  N  N   . ASN B 1 443 ? 204.976 220.542 207.283 1.00 56.64  ? 443 ASN B N   1 
ATOM   9609  C  CA  . ASN B 1 443 ? 204.509 219.644 206.231 1.00 56.64  ? 443 ASN B CA  1 
ATOM   9610  C  C   . ASN B 1 443 ? 204.585 220.308 204.864 1.00 56.64  ? 443 ASN B C   1 
ATOM   9611  O  O   . ASN B 1 443 ? 204.934 219.663 203.868 1.00 56.64  ? 443 ASN B O   1 
ATOM   9612  C  CB  . ASN B 1 443 ? 203.083 219.194 206.520 1.00 56.64  ? 443 ASN B CB  1 
ATOM   9613  C  CG  . ASN B 1 443 ? 202.502 218.374 205.398 1.00 56.64  ? 443 ASN B CG  1 
ATOM   9614  O  OD1 . ASN B 1 443 ? 202.977 217.280 205.107 1.00 56.64  ? 443 ASN B OD1 1 
ATOM   9615  N  ND2 . ASN B 1 443 ? 201.478 218.905 204.748 1.00 56.64  ? 443 ASN B ND2 1 
ATOM   9616  N  N   . ARG B 1 444 ? 204.243 221.595 204.796 1.00 53.53  ? 444 ARG B N   1 
ATOM   9617  C  CA  . ARG B 1 444 ? 204.382 222.333 203.543 1.00 53.53  ? 444 ARG B CA  1 
ATOM   9618  C  C   . ARG B 1 444 ? 205.828 222.322 203.064 1.00 53.53  ? 444 ARG B C   1 
ATOM   9619  O  O   . ARG B 1 444 ? 206.113 222.051 201.887 1.00 53.53  ? 444 ARG B O   1 
ATOM   9620  C  CB  . ARG B 1 444 ? 203.900 223.767 203.729 1.00 53.53  ? 444 ARG B CB  1 
ATOM   9621  C  CG  . ARG B 1 444 ? 202.405 223.907 203.776 1.00 53.53  ? 444 ARG B CG  1 
ATOM   9622  C  CD  . ARG B 1 444 ? 202.000 225.357 203.777 1.00 53.53  ? 444 ARG B CD  1 
ATOM   9623  N  NE  . ARG B 1 444 ? 200.554 225.495 203.863 1.00 53.53  ? 444 ARG B NE  1 
ATOM   9624  C  CZ  . ARG B 1 444 ? 199.911 226.653 203.879 1.00 53.53  ? 444 ARG B CZ  1 
ATOM   9625  N  NH1 . ARG B 1 444 ? 200.554 227.802 203.773 1.00 53.53  ? 444 ARG B NH1 1 
ATOM   9626  N  NH2 . ARG B 1 444 ? 198.591 226.658 204.028 1.00 53.53  ? 444 ARG B NH2 1 
ATOM   9627  N  N   . PHE B 1 445 ? 206.756 222.603 203.974 1.00 54.39  ? 445 PHE B N   1 
ATOM   9628  C  CA  . PHE B 1 445 ? 208.167 222.595 203.602 1.00 54.39  ? 445 PHE B CA  1 
ATOM   9629  C  C   . PHE B 1 445 ? 208.594 221.216 203.119 1.00 54.39  ? 445 PHE B C   1 
ATOM   9630  O  O   . PHE B 1 445 ? 209.319 221.090 202.122 1.00 54.39  ? 445 PHE B O   1 
ATOM   9631  C  CB  . PHE B 1 445 ? 209.028 223.036 204.781 1.00 54.39  ? 445 PHE B CB  1 
ATOM   9632  C  CG  . PHE B 1 445 ? 209.017 224.518 205.024 1.00 54.39  ? 445 PHE B CG  1 
ATOM   9633  C  CD1 . PHE B 1 445 ? 208.193 225.352 204.288 1.00 54.39  ? 445 PHE B CD1 1 
ATOM   9634  C  CD2 . PHE B 1 445 ? 209.829 225.076 205.996 1.00 54.39  ? 445 PHE B CD2 1 
ATOM   9635  C  CE1 . PHE B 1 445 ? 208.183 226.708 204.518 1.00 54.39  ? 445 PHE B CE1 1 
ATOM   9636  C  CE2 . PHE B 1 445 ? 209.820 226.434 206.227 1.00 54.39  ? 445 PHE B CE2 1 
ATOM   9637  C  CZ  . PHE B 1 445 ? 208.998 227.250 205.486 1.00 54.39  ? 445 PHE B CZ  1 
ATOM   9638  N  N   . ARG B 1 446 ? 208.144 220.170 203.811 1.00 55.27  ? 446 ARG B N   1 
ATOM   9639  C  CA  . ARG B 1 446 ? 208.509 218.807 203.444 1.00 55.27  ? 446 ARG B CA  1 
ATOM   9640  C  C   . ARG B 1 446 ? 207.999 218.460 202.054 1.00 55.27  ? 446 ARG B C   1 
ATOM   9641  O  O   . ARG B 1 446 ? 208.708 217.842 201.252 1.00 55.27  ? 446 ARG B O   1 
ATOM   9642  C  CB  . ARG B 1 446 ? 207.954 217.826 204.475 1.00 55.27  ? 446 ARG B CB  1 
ATOM   9643  C  CG  . ARG B 1 446 ? 208.692 217.822 205.798 1.00 55.27  ? 446 ARG B CG  1 
ATOM   9644  C  CD  . ARG B 1 446 ? 209.719 216.705 205.857 1.00 55.27  ? 446 ARG B CD  1 
ATOM   9645  N  NE  . ARG B 1 446 ? 210.074 216.377 207.232 1.00 55.27  ? 446 ARG B NE  1 
ATOM   9646  C  CZ  . ARG B 1 446 ? 209.270 215.764 208.089 1.00 55.27  ? 446 ARG B CZ  1 
ATOM   9647  N  NH1 . ARG B 1 446 ? 208.062 215.361 207.737 1.00 55.27  ? 446 ARG B NH1 1 
ATOM   9648  N  NH2 . ARG B 1 446 ? 209.692 215.544 209.330 1.00 55.27  ? 446 ARG B NH2 1 
ATOM   9649  N  N   . GLU B 1 447 ? 206.764 218.851 201.751 1.00 55.74  ? 447 GLU B N   1 
ATOM   9650  C  CA  . GLU B 1 447 ? 206.196 218.559 200.444 1.00 55.74  ? 447 GLU B CA  1 
ATOM   9651  C  C   . GLU B 1 447 ? 206.873 219.344 199.329 1.00 55.74  ? 447 GLU B C   1 
ATOM   9652  O  O   . GLU B 1 447 ? 206.912 218.865 198.192 1.00 55.74  ? 447 GLU B O   1 
ATOM   9653  C  CB  . GLU B 1 447 ? 204.696 218.847 200.453 1.00 55.74  ? 447 GLU B CB  1 
ATOM   9654  C  CG  . GLU B 1 447 ? 203.972 218.422 199.193 1.00 55.74  ? 447 GLU B CG  1 
ATOM   9655  C  CD  . GLU B 1 447 ? 202.468 218.537 199.323 1.00 55.74  ? 447 GLU B CD  1 
ATOM   9656  O  OE1 . GLU B 1 447 ? 201.983 218.742 200.455 1.00 55.74  ? 447 GLU B OE1 1 
ATOM   9657  O  OE2 . GLU B 1 447 ? 201.770 218.421 198.294 1.00 55.74  ? 447 GLU B OE2 1 
ATOM   9658  N  N   . LYS B 1 448 ? 207.407 220.532 199.615 1.00 51.16  ? 448 LYS B N   1 
ATOM   9659  C  CA  . LYS B 1 448 ? 207.990 221.339 198.550 1.00 51.16  ? 448 LYS B CA  1 
ATOM   9660  C  C   . LYS B 1 448 ? 209.512 221.306 198.465 1.00 51.16  ? 448 LYS B C   1 
ATOM   9661  O  O   . LYS B 1 448 ? 210.068 221.966 197.586 1.00 51.16  ? 448 LYS B O   1 
ATOM   9662  C  CB  . LYS B 1 448 ? 207.548 222.800 198.694 1.00 51.16  ? 448 LYS B CB  1 
ATOM   9663  C  CG  . LYS B 1 448 ? 206.077 223.010 198.406 1.00 51.16  ? 448 LYS B CG  1 
ATOM   9664  C  CD  . LYS B 1 448 ? 205.772 224.466 198.133 1.00 51.16  ? 448 LYS B CD  1 
ATOM   9665  C  CE  . LYS B 1 448 ? 206.708 225.029 197.088 1.00 51.16  ? 448 LYS B CE  1 
ATOM   9666  N  NZ  . LYS B 1 448 ? 206.760 224.178 195.869 1.00 51.16  ? 448 LYS B NZ  1 
ATOM   9667  N  N   . LEU B 1 449 ? 210.202 220.577 199.338 1.00 50.85  ? 449 LEU B N   1 
ATOM   9668  C  CA  . LEU B 1 449 ? 211.658 220.596 199.282 1.00 50.85  ? 449 LEU B CA  1 
ATOM   9669  C  C   . LEU B 1 449 ? 212.167 219.762 198.104 1.00 50.85  ? 449 LEU B C   1 
ATOM   9670  O  O   . LEU B 1 449 ? 211.402 219.144 197.362 1.00 50.85  ? 449 LEU B O   1 
ATOM   9671  C  CB  . LEU B 1 449 ? 212.258 220.117 200.605 1.00 50.85  ? 449 LEU B CB  1 
ATOM   9672  C  CG  . LEU B 1 449 ? 211.954 218.727 201.161 1.00 50.85  ? 449 LEU B CG  1 
ATOM   9673  C  CD1 . LEU B 1 449 ? 212.900 217.678 200.598 1.00 50.85  ? 449 LEU B CD1 1 
ATOM   9674  C  CD2 . LEU B 1 449 ? 212.054 218.759 202.673 1.00 50.85  ? 449 LEU B CD2 1 
ATOM   9675  N  N   . LYS B 1 450 ? 213.485 219.756 197.937 1.00 53.79  ? 450 LYS B N   1 
ATOM   9676  C  CA  . LYS B 1 450 ? 214.184 219.102 196.843 1.00 53.79  ? 450 LYS B CA  1 
ATOM   9677  C  C   . LYS B 1 450 ? 215.319 218.251 197.390 1.00 53.79  ? 450 LYS B C   1 
ATOM   9678  O  O   . LYS B 1 450 ? 215.821 218.505 198.489 1.00 53.79  ? 450 LYS B O   1 
ATOM   9679  C  CB  . LYS B 1 450 ? 214.734 220.138 195.852 1.00 53.79  ? 450 LYS B CB  1 
ATOM   9680  C  CG  . LYS B 1 450 ? 213.663 220.805 195.014 1.00 53.79  ? 450 LYS B CG  1 
ATOM   9681  C  CD  . LYS B 1 450 ? 214.266 221.744 193.987 1.00 53.79  ? 450 LYS B CD  1 
ATOM   9682  C  CE  . LYS B 1 450 ? 213.188 222.549 193.283 1.00 53.79  ? 450 LYS B CE  1 
ATOM   9683  N  NZ  . LYS B 1 450 ? 212.163 223.053 194.239 1.00 53.79  ? 450 LYS B NZ  1 
ATOM   9684  N  N   . PRO B 1 451 ? 215.741 217.222 196.650 1.00 55.07  ? 451 PRO B N   1 
ATOM   9685  C  CA  . PRO B 1 451 ? 216.729 216.276 197.201 1.00 55.07  ? 451 PRO B CA  1 
ATOM   9686  C  C   . PRO B 1 451 ? 218.093 216.876 197.478 1.00 55.07  ? 451 PRO B C   1 
ATOM   9687  O  O   . PRO B 1 451 ? 218.857 216.290 198.253 1.00 55.07  ? 451 PRO B O   1 
ATOM   9688  C  CB  . PRO B 1 451 ? 216.818 215.177 196.133 1.00 55.07  ? 451 PRO B CB  1 
ATOM   9689  C  CG  . PRO B 1 451 ? 215.718 215.425 195.173 1.00 55.07  ? 451 PRO B CG  1 
ATOM   9690  C  CD  . PRO B 1 451 ? 215.267 216.833 195.312 1.00 55.07  ? 451 PRO B CD  1 
ATOM   9691  N  N   . ASP B 1 452 ? 218.438 218.005 196.874 1.00 57.08  ? 452 ASP B N   1 
ATOM   9692  C  CA  . ASP B 1 452 ? 219.734 218.624 197.115 1.00 57.08  ? 452 ASP B CA  1 
ATOM   9693  C  C   . ASP B 1 452 ? 219.725 219.553 198.320 1.00 57.08  ? 452 ASP B C   1 
ATOM   9694  O  O   . ASP B 1 452 ? 220.758 220.151 198.632 1.00 57.08  ? 452 ASP B O   1 
ATOM   9695  C  CB  . ASP B 1 452 ? 220.187 219.397 195.873 1.00 57.08  ? 452 ASP B CB  1 
ATOM   9696  C  CG  . ASP B 1 452 ? 221.695 219.525 195.783 1.00 57.08  ? 452 ASP B CG  1 
ATOM   9697  O  OD1 . ASP B 1 452 ? 222.401 218.616 196.268 1.00 57.08  ? 452 ASP B OD1 1 
ATOM   9698  O  OD2 . ASP B 1 452 ? 222.175 220.535 195.227 1.00 57.08  ? 452 ASP B OD2 1 
ATOM   9699  N  N   . GLN B 1 453 ? 218.592 219.678 199.001 1.00 56.85  ? 453 GLN B N   1 
ATOM   9700  C  CA  . GLN B 1 453 ? 218.411 220.604 200.103 1.00 56.85  ? 453 GLN B CA  1 
ATOM   9701  C  C   . GLN B 1 453 ? 218.289 219.847 201.419 1.00 56.85  ? 453 GLN B C   1 
ATOM   9702  O  O   . GLN B 1 453 ? 217.974 218.655 201.451 1.00 56.85  ? 453 GLN B O   1 
ATOM   9703  C  CB  . GLN B 1 453 ? 217.167 221.468 199.884 1.00 56.85  ? 453 GLN B CB  1 
ATOM   9704  C  CG  . GLN B 1 453 ? 217.114 222.169 198.538 1.00 56.85  ? 453 GLN B CG  1 
ATOM   9705  C  CD  . GLN B 1 453 ? 215.858 222.991 198.375 1.00 56.85  ? 453 GLN B CD  1 
ATOM   9706  O  OE1 . GLN B 1 453 ? 214.837 222.706 198.994 1.00 56.85  ? 453 GLN B OE1 1 
ATOM   9707  N  NE2 . GLN B 1 453 ? 215.924 224.016 197.540 1.00 56.85  ? 453 GLN B NE2 1 
ATOM   9708  N  N   . TYR B 1 454 ? 218.546 220.562 202.514 1.00 67.59  ? 454 TYR B N   1 
ATOM   9709  C  CA  . TYR B 1 454 ? 218.465 219.994 203.857 1.00 67.59  ? 454 TYR B CA  1 
ATOM   9710  C  C   . TYR B 1 454 ? 217.649 220.921 204.747 1.00 67.59  ? 454 TYR B C   1 
ATOM   9711  O  O   . TYR B 1 454 ? 217.925 222.119 204.805 1.00 67.59  ? 454 TYR B O   1 
ATOM   9712  C  CB  . TYR B 1 454 ? 219.868 219.784 204.444 1.00 67.59  ? 454 TYR B CB  1 
ATOM   9713  C  CG  . TYR B 1 454 ? 219.895 219.367 205.896 1.00 67.59  ? 454 TYR B CG  1 
ATOM   9714  C  CD1 . TYR B 1 454 ? 219.799 218.033 206.254 1.00 67.59  ? 454 TYR B CD1 1 
ATOM   9715  C  CD2 . TYR B 1 454 ? 220.037 220.306 206.905 1.00 67.59  ? 454 TYR B CD2 1 
ATOM   9716  C  CE1 . TYR B 1 454 ? 219.829 217.644 207.574 1.00 67.59  ? 454 TYR B CE1 1 
ATOM   9717  C  CE2 . TYR B 1 454 ? 220.068 219.928 208.231 1.00 67.59  ? 454 TYR B CE2 1 
ATOM   9718  C  CZ  . TYR B 1 454 ? 219.964 218.595 208.560 1.00 67.59  ? 454 TYR B CZ  1 
ATOM   9719  O  OH  . TYR B 1 454 ? 219.995 218.212 209.882 1.00 67.59  ? 454 TYR B OH  1 
ATOM   9720  N  N   . LEU B 1 455 ? 216.661 220.374 205.447 1.00 64.49  ? 455 LEU B N   1 
ATOM   9721  C  CA  . LEU B 1 455 ? 215.779 221.163 206.297 1.00 64.49  ? 455 LEU B CA  1 
ATOM   9722  C  C   . LEU B 1 455 ? 216.017 220.817 207.759 1.00 64.49  ? 455 LEU B C   1 
ATOM   9723  O  O   . LEU B 1 455 ? 216.124 219.638 208.112 1.00 64.49  ? 455 LEU B O   1 
ATOM   9724  C  CB  . LEU B 1 455 ? 214.314 220.931 205.936 1.00 64.49  ? 455 LEU B CB  1 
ATOM   9725  C  CG  . LEU B 1 455 ? 213.310 221.862 206.609 1.00 64.49  ? 455 LEU B CG  1 
ATOM   9726  C  CD1 . LEU B 1 455 ? 213.519 223.291 206.166 1.00 64.49  ? 455 LEU B CD1 1 
ATOM   9727  C  CD2 . LEU B 1 455 ? 211.901 221.416 206.297 1.00 64.49  ? 455 LEU B CD2 1 
ATOM   9728  N  N   . CYS B 1 456 ? 216.093 221.845 208.603 1.00 71.88  ? 456 CYS B N   1 
ATOM   9729  C  CA  . CYS B 1 456 ? 216.317 221.673 210.031 1.00 71.88  ? 456 CYS B CA  1 
ATOM   9730  C  C   . CYS B 1 456 ? 215.577 222.763 210.791 1.00 71.88  ? 456 CYS B C   1 
ATOM   9731  O  O   . CYS B 1 456 ? 215.193 223.786 210.226 1.00 71.88  ? 456 CYS B O   1 
ATOM   9732  C  CB  . CYS B 1 456 ? 217.806 221.720 210.378 1.00 71.88  ? 456 CYS B CB  1 
ATOM   9733  S  SG  . CYS B 1 456 ? 218.147 221.588 212.139 1.00 71.88  ? 456 CYS B SG  1 
ATOM   9734  N  N   . ARG B 1 457 ? 215.380 222.534 212.087 1.00 71.81  ? 457 ARG B N   1 
ATOM   9735  C  CA  . ARG B 1 457 ? 214.766 223.512 212.978 1.00 71.81  ? 457 ARG B CA  1 
ATOM   9736  C  C   . ARG B 1 457 ? 215.688 223.724 214.168 1.00 71.81  ? 457 ARG B C   1 
ATOM   9737  O  O   . ARG B 1 457 ? 216.025 222.765 214.869 1.00 71.81  ? 457 ARG B O   1 
ATOM   9738  C  CB  . ARG B 1 457 ? 213.388 223.042 213.442 1.00 71.81  ? 457 ARG B CB  1 
ATOM   9739  C  CG  . ARG B 1 457 ? 212.650 224.053 214.292 1.00 71.81  ? 457 ARG B CG  1 
ATOM   9740  C  CD  . ARG B 1 457 ? 211.411 223.432 214.896 1.00 71.81  ? 457 ARG B CD  1 
ATOM   9741  N  NE  . ARG B 1 457 ? 211.777 222.407 215.863 1.00 71.81  ? 457 ARG B NE  1 
ATOM   9742  C  CZ  . ARG B 1 457 ? 211.901 222.621 217.164 1.00 71.81  ? 457 ARG B CZ  1 
ATOM   9743  N  NH1 . ARG B 1 457 ? 211.678 223.813 217.692 1.00 71.81  ? 457 ARG B NH1 1 
ATOM   9744  N  NH2 . ARG B 1 457 ? 212.265 221.616 217.955 1.00 71.81  ? 457 ARG B NH2 1 
ATOM   9745  N  N   . ILE B 1 458 ? 216.087 224.969 214.404 1.00 71.84  ? 458 ILE B N   1 
ATOM   9746  C  CA  . ILE B 1 458 ? 217.150 225.241 215.366 1.00 71.84  ? 458 ILE B CA  1 
ATOM   9747  C  C   . ILE B 1 458 ? 216.601 225.437 216.777 1.00 71.84  ? 458 ILE B C   1 
ATOM   9748  O  O   . ILE B 1 458 ? 216.929 224.674 217.690 1.00 71.84  ? 458 ILE B O   1 
ATOM   9749  C  CB  . ILE B 1 458 ? 217.987 226.448 214.896 1.00 71.84  ? 458 ILE B CB  1 
ATOM   9750  C  CG1 . ILE B 1 458 ? 217.087 227.592 214.448 1.00 71.84  ? 458 ILE B CG1 1 
ATOM   9751  C  CG2 . ILE B 1 458 ? 218.882 226.048 213.747 1.00 71.84  ? 458 ILE B CG2 1 
ATOM   9752  C  CD1 . ILE B 1 458 ? 217.828 228.869 214.189 1.00 71.84  ? 458 ILE B CD1 1 
ATOM   9753  N  N   . GLU B 1 459 ? 215.765 226.454 216.989 1.00 73.62  ? 459 GLU B N   1 
ATOM   9754  C  CA  . GLU B 1 459 ? 215.125 226.677 218.282 1.00 73.62  ? 459 GLU B CA  1 
ATOM   9755  C  C   . GLU B 1 459 ? 213.726 227.222 218.057 1.00 73.62  ? 459 GLU B C   1 
ATOM   9756  O  O   . GLU B 1 459 ? 213.565 228.278 217.440 1.00 73.62  ? 459 GLU B O   1 
ATOM   9757  C  CB  . GLU B 1 459 ? 215.907 227.659 219.169 1.00 73.62  ? 459 GLU B CB  1 
ATOM   9758  C  CG  . GLU B 1 459 ? 217.241 227.173 219.717 1.00 73.62  ? 459 GLU B CG  1 
ATOM   9759  C  CD  . GLU B 1 459 ? 218.398 227.395 218.771 1.00 73.62  ? 459 GLU B CD  1 
ATOM   9760  O  OE1 . GLU B 1 459 ? 218.188 227.993 217.696 1.00 73.62  ? 459 GLU B OE1 1 
ATOM   9761  O  OE2 . GLU B 1 459 ? 219.525 226.983 219.114 1.00 73.62  ? 459 GLU B OE2 1 
ATOM   9762  N  N   . GLY B 1 460 ? 212.727 226.515 218.578 1.00 72.35  ? 460 GLY B N   1 
ATOM   9763  C  CA  . GLY B 1 460 ? 211.370 227.023 218.596 1.00 72.35  ? 460 GLY B CA  1 
ATOM   9764  C  C   . GLY B 1 460 ? 210.746 227.205 217.230 1.00 72.35  ? 460 GLY B C   1 
ATOM   9765  O  O   . GLY B 1 460 ? 210.381 226.227 216.574 1.00 72.35  ? 460 GLY B O   1 
ATOM   9766  N  N   . THR B 1 461 ? 210.598 228.456 216.800 1.00 75.53  ? 461 THR B N   1 
ATOM   9767  C  CA  . THR B 1 461 ? 209.984 228.780 215.520 1.00 75.53  ? 461 THR B CA  1 
ATOM   9768  C  C   . THR B 1 461 ? 210.998 229.308 214.505 1.00 75.53  ? 461 THR B C   1 
ATOM   9769  O  O   . THR B 1 461 ? 210.661 230.147 213.666 1.00 75.53  ? 461 THR B O   1 
ATOM   9770  C  CB  . THR B 1 461 ? 208.854 229.789 215.714 1.00 75.53  ? 461 THR B CB  1 
ATOM   9771  O  OG1 . THR B 1 461 ? 209.400 231.107 215.851 1.00 75.53  ? 461 THR B OG1 1 
ATOM   9772  C  CG2 . THR B 1 461 ? 208.056 229.450 216.957 1.00 75.53  ? 461 THR B CG2 1 
ATOM   9773  N  N   . GLN B 1 462 ? 212.238 228.824 214.561 1.00 71.57  ? 462 GLN B N   1 
ATOM   9774  C  CA  . GLN B 1 462 ? 213.281 229.212 213.620 1.00 71.57  ? 462 GLN B CA  1 
ATOM   9775  C  C   . GLN B 1 462 ? 213.807 227.976 212.902 1.00 71.57  ? 462 GLN B C   1 
ATOM   9776  O  O   . GLN B 1 462 ? 214.176 226.990 213.548 1.00 71.57  ? 462 GLN B O   1 
ATOM   9777  C  CB  . GLN B 1 462 ? 214.418 229.941 214.334 1.00 71.57  ? 462 GLN B CB  1 
ATOM   9778  C  CG  . GLN B 1 462 ? 214.040 231.317 214.846 1.00 71.57  ? 462 GLN B CG  1 
ATOM   9779  C  CD  . GLN B 1 462 ? 215.248 232.160 215.212 1.00 71.57  ? 462 GLN B CD  1 
ATOM   9780  O  OE1 . GLN B 1 462 ? 215.738 232.952 214.407 1.00 71.57  ? 462 GLN B OE1 1 
ATOM   9781  N  NE2 . GLN B 1 462 ? 215.738 231.987 216.432 1.00 71.57  ? 462 GLN B NE2 1 
ATOM   9782  N  N   . PHE B 1 463 ? 213.847 228.036 211.568 1.00 68.68  ? 463 PHE B N   1 
ATOM   9783  C  CA  . PHE B 1 463 ? 214.218 226.910 210.722 1.00 68.68  ? 463 PHE B CA  1 
ATOM   9784  C  C   . PHE B 1 463 ? 215.361 227.319 209.801 1.00 68.68  ? 463 PHE B C   1 
ATOM   9785  O  O   . PHE B 1 463 ? 215.634 228.504 209.595 1.00 68.68  ? 463 PHE B O   1 
ATOM   9786  C  CB  . PHE B 1 463 ? 213.030 226.419 209.887 1.00 68.68  ? 463 PHE B CB  1 
ATOM   9787  C  CG  . PHE B 1 463 ? 211.846 225.984 210.697 1.00 68.68  ? 463 PHE B CG  1 
ATOM   9788  C  CD1 . PHE B 1 463 ? 211.030 226.911 211.315 1.00 68.68  ? 463 PHE B CD1 1 
ATOM   9789  C  CD2 . PHE B 1 463 ? 211.530 224.643 210.811 1.00 68.68  ? 463 PHE B CD2 1 
ATOM   9790  C  CE1 . PHE B 1 463 ? 209.939 226.509 212.050 1.00 68.68  ? 463 PHE B CE1 1 
ATOM   9791  C  CE2 . PHE B 1 463 ? 210.438 224.235 211.544 1.00 68.68  ? 463 PHE B CE2 1 
ATOM   9792  C  CZ  . PHE B 1 463 ? 209.641 225.169 212.165 1.00 68.68  ? 463 PHE B CZ  1 
ATOM   9793  N  N   . VAL B 1 464 ? 216.033 226.319 209.239 1.00 65.19  ? 464 VAL B N   1 
ATOM   9794  C  CA  . VAL B 1 464 ? 217.169 226.533 208.354 1.00 65.19  ? 464 VAL B CA  1 
ATOM   9795  C  C   . VAL B 1 464 ? 217.073 225.575 207.173 1.00 65.19  ? 464 VAL B C   1 
ATOM   9796  O  O   . VAL B 1 464 ? 216.806 224.380 207.344 1.00 65.19  ? 464 VAL B O   1 
ATOM   9797  C  CB  . VAL B 1 464 ? 218.506 226.348 209.096 1.00 65.19  ? 464 VAL B CB  1 
ATOM   9798  C  CG1 . VAL B 1 464 ? 219.654 226.330 208.110 1.00 65.19  ? 464 VAL B CG1 1 
ATOM   9799  C  CG2 . VAL B 1 464 ? 218.705 227.449 210.105 1.00 65.19  ? 464 VAL B CG2 1 
ATOM   9800  N  N   . LEU B 1 465 ? 217.294 226.108 205.972 1.00 64.03  ? 465 LEU B N   1 
ATOM   9801  C  CA  . LEU B 1 465 ? 217.344 225.322 204.742 1.00 64.03  ? 465 LEU B CA  1 
ATOM   9802  C  C   . LEU B 1 465 ? 218.719 225.481 204.114 1.00 64.03  ? 465 LEU B C   1 
ATOM   9803  O  O   . LEU B 1 465 ? 219.117 226.594 203.761 1.00 64.03  ? 465 LEU B O   1 
ATOM   9804  C  CB  . LEU B 1 465 ? 216.258 225.759 203.761 1.00 64.03  ? 465 LEU B CB  1 
ATOM   9805  C  CG  . LEU B 1 465 ? 216.219 224.986 202.448 1.00 64.03  ? 465 LEU B CG  1 
ATOM   9806  C  CD1 . LEU B 1 465 ? 215.876 223.533 202.704 1.00 64.03  ? 465 LEU B CD1 1 
ATOM   9807  C  CD2 . LEU B 1 465 ? 215.215 225.607 201.510 1.00 64.03  ? 465 LEU B CD2 1 
ATOM   9808  N  N   . VAL B 1 466 ? 219.437 224.379 203.974 1.00 62.85  ? 466 VAL B N   1 
ATOM   9809  C  CA  . VAL B 1 466 ? 220.774 224.378 203.401 1.00 62.85  ? 466 VAL B CA  1 
ATOM   9810  C  C   . VAL B 1 466 ? 220.663 223.961 201.945 1.00 62.85  ? 466 VAL B C   1 
ATOM   9811  O  O   . VAL B 1 466 ? 220.124 222.888 201.641 1.00 62.85  ? 466 VAL B O   1 
ATOM   9812  C  CB  . VAL B 1 466 ? 221.712 223.439 204.174 1.00 62.85  ? 466 VAL B CB  1 
ATOM   9813  C  CG1 . VAL B 1 466 ? 223.124 223.565 203.648 1.00 62.85  ? 466 VAL B CG1 1 
ATOM   9814  C  CG2 . VAL B 1 466 ? 221.665 223.755 205.655 1.00 62.85  ? 466 VAL B CG2 1 
ATOM   9815  N  N   . SER B 1 467 ? 221.159 224.812 201.047 1.00 62.10  ? 467 SER B N   1 
ATOM   9816  C  CA  . SER B 1 467 ? 221.122 224.564 199.616 1.00 62.10  ? 467 SER B CA  1 
ATOM   9817  C  C   . SER B 1 467 ? 222.520 224.732 199.039 1.00 62.10  ? 467 SER B C   1 
ATOM   9818  O  O   . SER B 1 467 ? 223.426 225.257 199.689 1.00 62.10  ? 467 SER B O   1 
ATOM   9819  C  CB  . SER B 1 467 ? 220.147 225.508 198.905 1.00 62.10  ? 467 SER B CB  1 
ATOM   9820  O  OG  . SER B 1 467 ? 220.412 225.546 197.515 1.00 62.10  ? 467 SER B OG  1 
ATOM   9821  N  N   . LEU B 1 468 ? 222.691 224.270 197.802 1.00 58.84  ? 468 LEU B N   1 
ATOM   9822  C  CA  . LEU B 1 468 ? 223.960 224.394 197.101 1.00 58.84  ? 468 LEU B CA  1 
ATOM   9823  C  C   . LEU B 1 468 ? 223.852 225.157 195.790 1.00 58.84  ? 468 LEU B C   1 
ATOM   9824  O  O   . LEU B 1 468 ? 224.867 225.318 195.103 1.00 58.84  ? 468 LEU B O   1 
ATOM   9825  C  CB  . LEU B 1 468 ? 224.567 223.010 196.834 1.00 58.84  ? 468 LEU B CB  1 
ATOM   9826  C  CG  . LEU B 1 468 ? 225.477 222.430 197.914 1.00 58.84  ? 468 LEU B CG  1 
ATOM   9827  C  CD1 . LEU B 1 468 ? 226.658 223.353 198.122 1.00 58.84  ? 468 LEU B CD1 1 
ATOM   9828  C  CD2 . LEU B 1 468 ? 224.745 222.194 199.211 1.00 58.84  ? 468 LEU B CD2 1 
ATOM   9829  N  N   . GLU B 1 469 ? 222.664 225.636 195.425 1.00 63.62  ? 469 GLU B N   1 
ATOM   9830  C  CA  . GLU B 1 469 ? 222.486 226.415 194.201 1.00 63.62  ? 469 GLU B CA  1 
ATOM   9831  C  C   . GLU B 1 469 ? 223.016 227.821 194.455 1.00 63.62  ? 469 GLU B C   1 
ATOM   9832  O  O   . GLU B 1 469 ? 222.290 228.740 194.837 1.00 63.62  ? 469 GLU B O   1 
ATOM   9833  C  CB  . GLU B 1 469 ? 221.024 226.425 193.780 1.00 63.62  ? 469 GLU B CB  1 
ATOM   9834  C  CG  . GLU B 1 469 ? 220.487 225.060 193.380 1.00 63.62  ? 469 GLU B CG  1 
ATOM   9835  C  CD  . GLU B 1 469 ? 219.008 225.088 193.045 1.00 63.62  ? 469 GLU B CD  1 
ATOM   9836  O  OE1 . GLU B 1 469 ? 218.373 226.146 193.239 1.00 63.62  ? 469 GLU B OE1 1 
ATOM   9837  O  OE2 . GLU B 1 469 ? 218.480 224.052 192.590 1.00 63.62  ? 469 GLU B OE2 1 
ATOM   9838  N  N   . ASN B 1 470 ? 224.315 227.988 194.232 1.00 61.25  ? 470 ASN B N   1 
ATOM   9839  C  CA  . ASN B 1 470 ? 225.004 229.226 194.582 1.00 61.25  ? 470 ASN B CA  1 
ATOM   9840  C  C   . ASN B 1 470 ? 225.088 230.160 193.376 1.00 61.25  ? 470 ASN B C   1 
ATOM   9841  O  O   . ASN B 1 470 ? 226.150 230.409 192.808 1.00 61.25  ? 470 ASN B O   1 
ATOM   9842  C  CB  . ASN B 1 470 ? 226.384 228.916 195.148 1.00 61.25  ? 470 ASN B CB  1 
ATOM   9843  C  CG  . ASN B 1 470 ? 227.139 227.899 194.318 1.00 61.25  ? 470 ASN B CG  1 
ATOM   9844  O  OD1 . ASN B 1 470 ? 226.687 227.497 193.246 1.00 61.25  ? 470 ASN B OD1 1 
ATOM   9845  N  ND2 . ASN B 1 470 ? 228.293 227.470 194.816 1.00 61.25  ? 470 ASN B ND2 1 
ATOM   9846  N  N   . ASP B 1 471 ? 223.931 230.698 193.006 1.00 63.41  ? 471 ASP B N   1 
ATOM   9847  C  CA  . ASP B 1 471 ? 223.858 231.759 192.010 1.00 63.41  ? 471 ASP B CA  1 
ATOM   9848  C  C   . ASP B 1 471 ? 222.567 232.531 192.221 1.00 63.41  ? 471 ASP B C   1 
ATOM   9849  O  O   . ASP B 1 471 ? 221.564 231.983 192.689 1.00 63.41  ? 471 ASP B O   1 
ATOM   9850  C  CB  . ASP B 1 471 ? 223.950 231.212 190.582 1.00 63.41  ? 471 ASP B CB  1 
ATOM   9851  C  CG  . ASP B 1 471 ? 222.905 230.158 190.290 1.00 63.41  ? 471 ASP B CG  1 
ATOM   9852  O  OD1 . ASP B 1 471 ? 222.238 229.702 191.238 1.00 63.41  ? 471 ASP B OD1 1 
ATOM   9853  O  OD2 . ASP B 1 471 ? 222.750 229.785 189.108 1.00 63.41  ? 471 ASP B OD2 1 
ATOM   9854  N  N   . VAL B 1 472 ? 222.605 233.814 191.860 1.00 59.09  ? 472 VAL B N   1 
ATOM   9855  C  CA  . VAL B 1 472 ? 221.517 234.718 192.217 1.00 59.09  ? 472 VAL B CA  1 
ATOM   9856  C  C   . VAL B 1 472 ? 220.206 234.251 191.608 1.00 59.09  ? 472 VAL B C   1 
ATOM   9857  O  O   . VAL B 1 472 ? 219.143 234.348 192.235 1.00 59.09  ? 472 VAL B O   1 
ATOM   9858  C  CB  . VAL B 1 472 ? 221.856 236.155 191.790 1.00 59.09  ? 472 VAL B CB  1 
ATOM   9859  C  CG1 . VAL B 1 472 ? 220.746 237.102 192.194 1.00 59.09  ? 472 VAL B CG1 1 
ATOM   9860  C  CG2 . VAL B 1 472 ? 223.176 236.586 192.401 1.00 59.09  ? 472 VAL B CG2 1 
ATOM   9861  N  N   . SER B 1 473 ? 220.260 233.728 190.381 1.00 62.59  ? 473 SER B N   1 
ATOM   9862  C  CA  . SER B 1 473 ? 219.038 233.344 189.685 1.00 62.59  ? 473 SER B CA  1 
ATOM   9863  C  C   . SER B 1 473 ? 218.298 232.242 190.429 1.00 62.59  ? 473 SER B C   1 
ATOM   9864  O  O   . SER B 1 473 ? 217.068 232.280 190.545 1.00 62.59  ? 473 SER B O   1 
ATOM   9865  C  CB  . SER B 1 473 ? 219.363 232.904 188.258 1.00 62.59  ? 473 SER B CB  1 
ATOM   9866  O  OG  . SER B 1 473 ? 220.133 231.715 188.252 1.00 62.59  ? 473 SER B OG  1 
ATOM   9867  N  N   . ASN B 1 474 ? 219.026 231.248 190.933 1.00 62.59  ? 474 ASN B N   1 
ATOM   9868  C  CA  . ASN B 1 474 ? 218.380 230.193 191.702 1.00 62.59  ? 474 ASN B CA  1 
ATOM   9869  C  C   . ASN B 1 474 ? 218.025 230.651 193.107 1.00 62.59  ? 474 ASN B C   1 
ATOM   9870  O  O   . ASN B 1 474 ? 216.996 230.228 193.653 1.00 62.59  ? 474 ASN B O   1 
ATOM   9871  C  CB  . ASN B 1 474 ? 219.278 228.960 191.765 1.00 62.59  ? 474 ASN B CB  1 
ATOM   9872  C  CG  . ASN B 1 474 ? 219.372 228.242 190.436 1.00 62.59  ? 474 ASN B CG  1 
ATOM   9873  O  OD1 . ASN B 1 474 ? 220.114 228.653 189.545 1.00 62.59  ? 474 ASN B OD1 1 
ATOM   9874  N  ND2 . ASN B 1 474 ? 218.621 227.157 190.297 1.00 62.59  ? 474 ASN B ND2 1 
ATOM   9875  N  N   . ILE B 1 475 ? 218.855 231.510 193.699 1.00 58.14  ? 475 ILE B N   1 
ATOM   9876  C  CA  . ILE B 1 475 ? 218.623 231.949 195.069 1.00 58.14  ? 475 ILE B CA  1 
ATOM   9877  C  C   . ILE B 1 475 ? 217.321 232.730 195.169 1.00 58.14  ? 475 ILE B C   1 
ATOM   9878  O  O   . ILE B 1 475 ? 216.495 232.472 196.053 1.00 58.14  ? 475 ILE B O   1 
ATOM   9879  C  CB  . ILE B 1 475 ? 219.818 232.775 195.570 1.00 58.14  ? 475 ILE B CB  1 
ATOM   9880  C  CG1 . ILE B 1 475 ? 221.028 231.869 195.782 1.00 58.14  ? 475 ILE B CG1 1 
ATOM   9881  C  CG2 . ILE B 1 475 ? 219.463 233.530 196.832 1.00 58.14  ? 475 ILE B CG2 1 
ATOM   9882  C  CD1 . ILE B 1 475 ? 220.888 230.919 196.924 1.00 58.14  ? 475 ILE B CD1 1 
ATOM   9883  N  N   . THR B 1 476 ? 217.113 233.693 194.267 1.00 57.08  ? 476 THR B N   1 
ATOM   9884  C  CA  . THR B 1 476 ? 215.880 234.474 194.320 1.00 57.08  ? 476 THR B CA  1 
ATOM   9885  C  C   . THR B 1 476 ? 214.661 233.593 194.095 1.00 57.08  ? 476 THR B C   1 
ATOM   9886  O  O   . THR B 1 476 ? 213.643 233.747 194.775 1.00 57.08  ? 476 THR B O   1 
ATOM   9887  C  CB  . THR B 1 476 ? 215.903 235.615 193.302 1.00 57.08  ? 476 THR B CB  1 
ATOM   9888  O  OG1 . THR B 1 476 ? 214.628 236.265 193.296 1.00 57.08  ? 476 THR B OG1 1 
ATOM   9889  C  CG2 . THR B 1 476 ? 216.193 235.108 191.911 1.00 57.08  ? 476 THR B CG2 1 
ATOM   9890  N  N   . GLN B 1 477 ? 214.752 232.652 193.156 1.00 62.86  ? 477 GLN B N   1 
ATOM   9891  C  CA  . GLN B 1 477 ? 213.626 231.774 192.876 1.00 62.86  ? 477 GLN B CA  1 
ATOM   9892  C  C   . GLN B 1 477 ? 213.256 230.949 194.100 1.00 62.86  ? 477 GLN B C   1 
ATOM   9893  O  O   . GLN B 1 477 ? 212.084 230.895 194.497 1.00 62.86  ? 477 GLN B O   1 
ATOM   9894  C  CB  . GLN B 1 477 ? 213.960 230.866 191.694 1.00 62.86  ? 477 GLN B CB  1 
ATOM   9895  C  CG  . GLN B 1 477 ? 212.759 230.169 191.090 1.00 62.86  ? 477 GLN B CG  1 
ATOM   9896  C  CD  . GLN B 1 477 ? 213.133 229.287 189.917 1.00 62.86  ? 477 GLN B CD  1 
ATOM   9897  O  OE1 . GLN B 1 477 ? 214.202 228.676 189.902 1.00 62.86  ? 477 GLN B OE1 1 
ATOM   9898  N  NE2 . GLN B 1 477 ? 212.253 229.215 188.926 1.00 62.86  ? 477 GLN B NE2 1 
ATOM   9899  N  N   . ILE B 1 478 ? 214.245 230.302 194.723 1.00 60.60  ? 478 ILE B N   1 
ATOM   9900  C  CA  . ILE B 1 478 ? 213.928 229.423 195.843 1.00 60.60  ? 478 ILE B CA  1 
ATOM   9901  C  C   . ILE B 1 478 ? 213.461 230.233 197.046 1.00 60.60  ? 478 ILE B C   1 
ATOM   9902  O  O   . ILE B 1 478 ? 212.547 229.817 197.767 1.00 60.60  ? 478 ILE B O   1 
ATOM   9903  C  CB  . ILE B 1 478 ? 215.121 228.509 196.180 1.00 60.60  ? 478 ILE B CB  1 
ATOM   9904  C  CG1 . ILE B 1 478 ? 214.747 227.537 197.298 1.00 60.60  ? 478 ILE B CG1 1 
ATOM   9905  C  CG2 . ILE B 1 478 ? 216.321 229.305 196.579 1.00 60.60  ? 478 ILE B CG2 1 
ATOM   9906  C  CD1 . ILE B 1 478 ? 213.504 226.726 197.013 1.00 60.60  ? 478 ILE B CD1 1 
ATOM   9907  N  N   . ALA B 1 479 ? 214.056 231.406 197.275 1.00 60.04  ? 479 ALA B N   1 
ATOM   9908  C  CA  . ALA B 1 479 ? 213.612 232.238 198.387 1.00 60.04  ? 479 ALA B CA  1 
ATOM   9909  C  C   . ALA B 1 479 ? 212.180 232.710 198.183 1.00 60.04  ? 479 ALA B C   1 
ATOM   9910  O  O   . ALA B 1 479 ? 211.376 232.710 199.124 1.00 60.04  ? 479 ALA B O   1 
ATOM   9911  C  CB  . ALA B 1 479 ? 214.553 233.428 198.559 1.00 60.04  ? 479 ALA B CB  1 
ATOM   9912  N  N   . ASP B 1 480 ? 211.839 233.115 196.959 1.00 59.30  ? 480 ASP B N   1 
ATOM   9913  C  CA  . ASP B 1 480 ? 210.478 233.542 196.679 1.00 59.30  ? 480 ASP B CA  1 
ATOM   9914  C  C   . ASP B 1 480 ? 209.498 232.395 196.853 1.00 59.30  ? 480 ASP B C   1 
ATOM   9915  O  O   . ASP B 1 480 ? 208.403 232.585 197.390 1.00 59.30  ? 480 ASP B O   1 
ATOM   9916  C  CB  . ASP B 1 480 ? 210.390 234.117 195.269 1.00 59.30  ? 480 ASP B CB  1 
ATOM   9917  C  CG  . ASP B 1 480 ? 211.064 235.464 195.151 1.00 59.30  ? 480 ASP B CG  1 
ATOM   9918  O  OD1 . ASP B 1 480 ? 211.105 236.199 196.159 1.00 59.30  ? 480 ASP B OD1 1 
ATOM   9919  O  OD2 . ASP B 1 480 ? 211.555 235.792 194.049 1.00 59.30  ? 480 ASP B OD2 1 
ATOM   9920  N  N   . GLU B 1 481 ? 209.870 231.194 196.410 1.00 59.33  ? 481 GLU B N   1 
ATOM   9921  C  CA  . GLU B 1 481 ? 208.984 230.051 196.598 1.00 59.33  ? 481 GLU B CA  1 
ATOM   9922  C  C   . GLU B 1 481 ? 208.774 229.746 198.078 1.00 59.33  ? 481 GLU B C   1 
ATOM   9923  O  O   . GLU B 1 481 ? 207.642 229.484 198.507 1.00 59.33  ? 481 GLU B O   1 
ATOM   9924  C  CB  . GLU B 1 481 ? 209.538 228.832 195.868 1.00 59.33  ? 481 GLU B CB  1 
ATOM   9925  C  CG  . GLU B 1 481 ? 208.537 227.708 195.723 1.00 59.33  ? 481 GLU B CG  1 
ATOM   9926  C  CD  . GLU B 1 481 ? 207.372 228.076 194.825 1.00 59.33  ? 481 GLU B CD  1 
ATOM   9927  O  OE1 . GLU B 1 481 ? 207.559 228.909 193.914 1.00 59.33  ? 481 GLU B OE1 1 
ATOM   9928  O  OE2 . GLU B 1 481 ? 206.266 227.534 195.032 1.00 59.33  ? 481 GLU B OE2 1 
ATOM   9929  N  N   . LEU B 1 482 ? 209.849 229.784 198.875 1.00 54.91  ? 482 LEU B N   1 
ATOM   9930  C  CA  . LEU B 1 482 ? 209.719 229.552 200.310 1.00 54.91  ? 482 LEU B CA  1 
ATOM   9931  C  C   . LEU B 1 482 ? 208.807 230.585 200.948 1.00 54.91  ? 482 LEU B C   1 
ATOM   9932  O  O   . LEU B 1 482 ? 207.960 230.252 201.781 1.00 54.91  ? 482 LEU B O   1 
ATOM   9933  C  CB  . LEU B 1 482 ? 211.086 229.583 200.987 1.00 54.91  ? 482 LEU B CB  1 
ATOM   9934  C  CG  . LEU B 1 482 ? 211.886 228.292 201.061 1.00 54.91  ? 482 LEU B CG  1 
ATOM   9935  C  CD1 . LEU B 1 482 ? 213.314 228.608 201.432 1.00 54.91  ? 482 LEU B CD1 1 
ATOM   9936  C  CD2 . LEU B 1 482 ? 211.270 227.343 202.069 1.00 54.91  ? 482 LEU B CD2 1 
ATOM   9937  N  N   . ARG B 1 483 ? 208.968 231.851 200.572 1.00 58.85  ? 483 ARG B N   1 
ATOM   9938  C  CA  . ARG B 1 483 ? 208.093 232.884 201.113 1.00 58.85  ? 483 ARG B CA  1 
ATOM   9939  C  C   . ARG B 1 483 ? 206.652 232.678 200.660 1.00 58.85  ? 483 ARG B C   1 
ATOM   9940  O  O   . ARG B 1 483 ? 205.710 232.991 201.397 1.00 58.85  ? 483 ARG B O   1 
ATOM   9941  C  CB  . ARG B 1 483 ? 208.600 234.262 200.701 1.00 58.85  ? 483 ARG B CB  1 
ATOM   9942  C  CG  . ARG B 1 483 ? 207.708 235.401 201.122 1.00 58.85  ? 483 ARG B CG  1 
ATOM   9943  C  CD  . ARG B 1 483 ? 208.381 236.734 200.897 1.00 58.85  ? 483 ARG B CD  1 
ATOM   9944  N  NE  . ARG B 1 483 ? 207.476 237.846 201.158 1.00 58.85  ? 483 ARG B NE  1 
ATOM   9945  C  CZ  . ARG B 1 483 ? 206.714 238.421 200.238 1.00 58.85  ? 483 ARG B CZ  1 
ATOM   9946  N  NH1 . ARG B 1 483 ? 206.723 238.013 198.979 1.00 58.85  ? 483 ARG B NH1 1 
ATOM   9947  N  NH2 . ARG B 1 483 ? 205.923 239.431 200.589 1.00 58.85  ? 483 ARG B NH2 1 
ATOM   9948  N  N   . ASN B 1 484 ? 206.460 232.145 199.451 1.00 56.05  ? 484 ASN B N   1 
ATOM   9949  C  CA  . ASN B 1 484 ? 205.115 232.011 198.902 1.00 56.05  ? 484 ASN B CA  1 
ATOM   9950  C  C   . ASN B 1 484 ? 204.375 230.804 199.455 1.00 56.05  ? 484 ASN B C   1 
ATOM   9951  O  O   . ASN B 1 484 ? 203.145 230.755 199.366 1.00 56.05  ? 484 ASN B O   1 
ATOM   9952  C  CB  . ASN B 1 484 ? 205.176 231.914 197.380 1.00 56.05  ? 484 ASN B CB  1 
ATOM   9953  C  CG  . ASN B 1 484 ? 205.605 233.207 196.732 1.00 56.05  ? 484 ASN B CG  1 
ATOM   9954  O  OD1 . ASN B 1 484 ? 205.317 234.292 197.235 1.00 56.05  ? 484 ASN B OD1 1 
ATOM   9955  N  ND2 . ASN B 1 484 ? 206.309 233.102 195.612 1.00 56.05  ? 484 ASN B ND2 1 
ATOM   9956  N  N   . VAL B 1 485 ? 205.088 229.819 200.004 1.00 55.15  ? 485 VAL B N   1 
ATOM   9957  C  CA  . VAL B 1 485 ? 204.427 228.597 200.470 1.00 55.15  ? 485 VAL B CA  1 
ATOM   9958  C  C   . VAL B 1 485 ? 203.304 228.914 201.448 1.00 55.15  ? 485 VAL B C   1 
ATOM   9959  O  O   . VAL B 1 485 ? 202.379 228.114 201.619 1.00 55.15  ? 485 VAL B O   1 
ATOM   9960  C  CB  . VAL B 1 485 ? 205.406 227.602 201.125 1.00 55.15  ? 485 VAL B CB  1 
ATOM   9961  C  CG1 . VAL B 1 485 ? 206.585 227.300 200.226 1.00 55.15  ? 485 VAL B CG1 1 
ATOM   9962  C  CG2 . VAL B 1 485 ? 205.859 228.099 202.482 1.00 55.15  ? 485 VAL B CG2 1 
ATOM   9963  N  N   . VAL B 1 486 ? 203.366 230.071 202.097 1.00 55.20  ? 486 VAL B N   1 
ATOM   9964  C  CA  . VAL B 1 486 ? 202.369 230.447 203.085 1.00 55.20  ? 486 VAL B CA  1 
ATOM   9965  C  C   . VAL B 1 486 ? 201.300 231.362 202.487 1.00 55.20  ? 486 VAL B C   1 
ATOM   9966  O  O   . VAL B 1 486 ? 200.582 232.032 203.224 1.00 55.20  ? 486 VAL B O   1 
ATOM   9967  C  CB  . VAL B 1 486 ? 203.015 231.087 204.321 1.00 55.20  ? 486 VAL B CB  1 
ATOM   9968  C  CG1 . VAL B 1 486 ? 203.984 230.118 204.969 1.00 55.20  ? 486 VAL B CG1 1 
ATOM   9969  C  CG2 . VAL B 1 486 ? 203.718 232.378 203.941 1.00 55.20  ? 486 VAL B CG2 1 
ATOM   9970  N  N   . SER B 1 487 ? 201.184 231.402 201.159 1.00 54.40  ? 487 SER B N   1 
ATOM   9971  C  CA  . SER B 1 487 ? 200.142 232.206 200.534 1.00 54.40  ? 487 SER B CA  1 
ATOM   9972  C  C   . SER B 1 487 ? 198.748 231.739 200.917 1.00 54.40  ? 487 SER B C   1 
ATOM   9973  O  O   . SER B 1 487 ? 197.888 232.574 201.210 1.00 54.40  ? 487 SER B O   1 
ATOM   9974  C  CB  . SER B 1 487 ? 200.290 232.176 199.015 1.00 54.40  ? 487 SER B CB  1 
ATOM   9975  O  OG  . SER B 1 487 ? 200.017 230.882 198.508 1.00 54.40  ? 487 SER B OG  1 
ATOM   9976  N  N   . LYS B 1 488 ? 198.502 230.435 200.915 1.00 53.49  ? 488 LYS B N   1 
ATOM   9977  C  CA  . LYS B 1 488 ? 197.250 229.896 201.408 1.00 53.49  ? 488 LYS B CA  1 
ATOM   9978  C  C   . LYS B 1 488 ? 197.296 229.792 202.924 1.00 53.49  ? 488 LYS B C   1 
ATOM   9979  O  O   . LYS B 1 488 ? 198.222 229.184 203.478 1.00 53.49  ? 488 LYS B O   1 
ATOM   9980  C  CB  . LYS B 1 488 ? 196.954 228.528 200.774 1.00 53.49  ? 488 LYS B CB  1 
ATOM   9981  C  CG  . LYS B 1 488 ? 197.962 227.431 201.070 1.00 53.49  ? 488 LYS B CG  1 
ATOM   9982  C  CD  . LYS B 1 488 ? 197.557 226.109 200.441 1.00 53.49  ? 488 LYS B CD  1 
ATOM   9983  C  CE  . LYS B 1 488 ? 197.732 226.145 198.935 1.00 53.49  ? 488 LYS B CE  1 
ATOM   9984  N  NZ  . LYS B 1 488 ? 199.165 226.273 198.556 1.00 53.49  ? 488 LYS B NZ  1 
ATOM   9985  N  N   . PRO B 1 489 ? 196.342 230.403 203.620 1.00 56.56  ? 489 PRO B N   1 
ATOM   9986  C  CA  . PRO B 1 489 ? 196.428 230.482 205.082 1.00 56.56  ? 489 PRO B CA  1 
ATOM   9987  C  C   . PRO B 1 489 ? 196.419 229.111 205.737 1.00 56.56  ? 489 PRO B C   1 
ATOM   9988  O  O   . PRO B 1 489 ? 195.764 228.179 205.267 1.00 56.56  ? 489 PRO B O   1 
ATOM   9989  C  CB  . PRO B 1 489 ? 195.185 231.292 205.464 1.00 56.56  ? 489 PRO B CB  1 
ATOM   9990  C  CG  . PRO B 1 489 ? 194.256 231.131 204.307 1.00 56.56  ? 489 PRO B CG  1 
ATOM   9991  C  CD  . PRO B 1 489 ? 195.129 231.048 203.098 1.00 56.56  ? 489 PRO B CD  1 
ATOM   9992  N  N   . ILE B 1 490 ? 197.159 229.000 206.842 1.00 60.09  ? 490 ILE B N   1 
ATOM   9993  C  CA  . ILE B 1 490 ? 197.141 227.773 207.622 1.00 60.09  ? 490 ILE B CA  1 
ATOM   9994  C  C   . ILE B 1 490 ? 195.772 227.600 208.260 1.00 60.09  ? 490 ILE B C   1 
ATOM   9995  O  O   . ILE B 1 490 ? 195.260 228.489 208.951 1.00 60.09  ? 490 ILE B O   1 
ATOM   9996  C  CB  . ILE B 1 490 ? 198.244 227.785 208.692 1.00 60.09  ? 490 ILE B CB  1 
ATOM   9997  C  CG1 . ILE B 1 490 ? 199.616 227.749 208.026 1.00 60.09  ? 490 ILE B CG1 1 
ATOM   9998  C  CG2 . ILE B 1 490 ? 198.073 226.622 209.643 1.00 60.09  ? 490 ILE B CG2 1 
ATOM   9999  C  CD1 . ILE B 1 490 ? 199.927 226.432 207.371 1.00 60.09  ? 490 ILE B CD1 1 
ATOM   10000 N  N   . MET B 1 491 ? 195.171 226.442 208.024 1.00 64.36  ? 491 MET B N   1 
ATOM   10001 C  CA  . MET B 1 491 ? 193.853 226.118 208.543 1.00 64.36  ? 491 MET B CA  1 
ATOM   10002 C  C   . MET B 1 491 ? 194.010 225.234 209.769 1.00 64.36  ? 491 MET B C   1 
ATOM   10003 O  O   . MET B 1 491 ? 194.601 224.153 209.687 1.00 64.36  ? 491 MET B O   1 
ATOM   10004 C  CB  . MET B 1 491 ? 193.012 225.420 207.476 1.00 64.36  ? 491 MET B CB  1 
ATOM   10005 C  CG  . MET B 1 491 ? 192.020 226.327 206.784 1.00 64.36  ? 491 MET B CG  1 
ATOM   10006 S  SD  . MET B 1 491 ? 190.633 226.714 207.856 1.00 64.36  ? 491 MET B SD  1 
ATOM   10007 C  CE  . MET B 1 491 ? 189.927 225.080 208.039 1.00 64.36  ? 491 MET B CE  1 
ATOM   10008 N  N   . ILE B 1 492 ? 193.489 225.698 210.901 1.00 63.82  ? 492 ILE B N   1 
ATOM   10009 C  CA  . ILE B 1 492 ? 193.550 224.942 212.144 1.00 63.82  ? 492 ILE B CA  1 
ATOM   10010 C  C   . ILE B 1 492 ? 192.168 224.926 212.779 1.00 63.82  ? 492 ILE B C   1 
ATOM   10011 O  O   . ILE B 1 492 ? 191.772 225.880 213.458 1.00 63.82  ? 492 ILE B O   1 
ATOM   10012 C  CB  . ILE B 1 492 ? 194.600 225.530 213.100 1.00 63.82  ? 492 ILE B CB  1 
ATOM   10013 C  CG1 . ILE B 1 492 ? 195.999 225.420 212.493 1.00 63.82  ? 492 ILE B CG1 1 
ATOM   10014 C  CG2 . ILE B 1 492 ? 194.563 224.823 214.431 1.00 63.82  ? 492 ILE B CG2 1 
ATOM   10015 C  CD1 . ILE B 1 492 ? 196.515 224.001 212.402 1.00 63.82  ? 492 ILE B CD1 1 
ATOM   10016 N  N   . ASP B 1 493 ? 191.419 223.852 212.540 1.00 65.55  ? 493 ASP B N   1 
ATOM   10017 C  CA  . ASP B 1 493 ? 190.091 223.651 213.112 1.00 65.55  ? 493 ASP B CA  1 
ATOM   10018 C  C   . ASP B 1 493 ? 189.137 224.782 212.731 1.00 65.55  ? 493 ASP B C   1 
ATOM   10019 O  O   . ASP B 1 493 ? 188.642 225.529 213.576 1.00 65.55  ? 493 ASP B O   1 
ATOM   10020 C  CB  . ASP B 1 493 ? 190.173 223.496 214.631 1.00 65.55  ? 493 ASP B CB  1 
ATOM   10021 C  CG  . ASP B 1 493 ? 188.922 222.878 215.220 1.00 65.55  ? 493 ASP B CG  1 
ATOM   10022 O  OD1 . ASP B 1 493 ? 187.996 222.556 214.448 1.00 65.55  ? 493 ASP B OD1 1 
ATOM   10023 O  OD2 . ASP B 1 493 ? 188.865 222.714 216.457 1.00 65.55  ? 493 ASP B OD2 1 
ATOM   10024 N  N   . ASP B 1 494 ? 188.889 224.899 211.428 1.00 66.17  ? 494 ASP B N   1 
ATOM   10025 C  CA  . ASP B 1 494 ? 187.884 225.788 210.851 1.00 66.17  ? 494 ASP B CA  1 
ATOM   10026 C  C   . ASP B 1 494 ? 188.088 227.252 211.218 1.00 66.17  ? 494 ASP B C   1 
ATOM   10027 O  O   . ASP B 1 494 ? 187.107 228.001 211.308 1.00 66.17  ? 494 ASP B O   1 
ATOM   10028 C  CB  . ASP B 1 494 ? 186.467 225.362 211.245 1.00 66.17  ? 494 ASP B CB  1 
ATOM   10029 C  CG  . ASP B 1 494 ? 186.058 224.049 210.611 1.00 66.17  ? 494 ASP B CG  1 
ATOM   10030 O  OD1 . ASP B 1 494 ? 186.556 223.741 209.508 1.00 66.17  ? 494 ASP B OD1 1 
ATOM   10031 O  OD2 . ASP B 1 494 ? 185.239 223.325 211.215 1.00 66.17  ? 494 ASP B OD2 1 
ATOM   10032 N  N   . LYS B 1 495 ? 189.322 227.685 211.434 1.00 66.03  ? 495 LYS B N   1 
ATOM   10033 C  CA  . LYS B 1 495 ? 189.617 229.083 211.743 1.00 66.03  ? 495 LYS B CA  1 
ATOM   10034 C  C   . LYS B 1 495 ? 190.852 229.523 210.976 1.00 66.03  ? 495 LYS B C   1 
ATOM   10035 O  O   . LYS B 1 495 ? 191.972 229.095 211.316 1.00 66.03  ? 495 LYS B O   1 
ATOM   10036 C  CB  . LYS B 1 495 ? 189.824 229.278 213.244 1.00 66.03  ? 495 LYS B CB  1 
ATOM   10037 C  CG  . LYS B 1 495 ? 189.976 230.731 213.657 1.00 66.03  ? 495 LYS B CG  1 
ATOM   10038 C  CD  . LYS B 1 495 ? 190.070 230.869 215.167 1.00 66.03  ? 495 LYS B CD  1 
ATOM   10039 C  CE  . LYS B 1 495 ? 188.735 230.572 215.830 1.00 66.03  ? 495 LYS B CE  1 
ATOM   10040 N  NZ  . LYS B 1 495 ? 187.706 231.589 215.478 1.00 66.03  ? 495 LYS B NZ  1 
ATOM   10041 N  N   . PRO B 1 496 ? 190.716 230.368 209.961 1.00 66.41  ? 496 PRO B N   1 
ATOM   10042 C  CA  . PRO B 1 496 ? 191.873 230.747 209.147 1.00 66.41  ? 496 PRO B CA  1 
ATOM   10043 C  C   . PRO B 1 496 ? 192.885 231.549 209.949 1.00 66.41  ? 496 PRO B C   1 
ATOM   10044 O  O   . PRO B 1 496 ? 192.565 232.220 210.931 1.00 66.41  ? 496 PRO B O   1 
ATOM   10045 C  CB  . PRO B 1 496 ? 191.258 231.589 208.029 1.00 66.41  ? 496 PRO B CB  1 
ATOM   10046 C  CG  . PRO B 1 496 ? 190.009 232.132 208.623 1.00 66.41  ? 496 PRO B CG  1 
ATOM   10047 C  CD  . PRO B 1 496 ? 189.488 231.047 209.521 1.00 66.41  ? 496 PRO B CD  1 
ATOM   10048 N  N   . PHE B 1 497 ? 194.135 231.466 209.505 1.00 65.19  ? 497 PHE B N   1 
ATOM   10049 C  CA  . PHE B 1 497 ? 195.228 232.182 210.143 1.00 65.19  ? 497 PHE B CA  1 
ATOM   10050 C  C   . PHE B 1 497 ? 196.278 232.556 209.106 1.00 65.19  ? 497 PHE B C   1 
ATOM   10051 O  O   . PHE B 1 497 ? 196.992 231.683 208.598 1.00 65.19  ? 497 PHE B O   1 
ATOM   10052 C  CB  . PHE B 1 497 ? 195.851 231.338 211.252 1.00 65.19  ? 497 PHE B CB  1 
ATOM   10053 C  CG  . PHE B 1 497 ? 195.104 231.400 212.549 1.00 65.19  ? 497 PHE B CG  1 
ATOM   10054 C  CD1 . PHE B 1 497 ? 194.996 232.592 213.242 1.00 65.19  ? 497 PHE B CD1 1 
ATOM   10055 C  CD2 . PHE B 1 497 ? 194.519 230.268 213.080 1.00 65.19  ? 497 PHE B CD2 1 
ATOM   10056 C  CE1 . PHE B 1 497 ? 194.314 232.651 214.439 1.00 65.19  ? 497 PHE B CE1 1 
ATOM   10057 C  CE2 . PHE B 1 497 ? 193.839 230.320 214.273 1.00 65.19  ? 497 PHE B CE2 1 
ATOM   10058 C  CZ  . PHE B 1 497 ? 193.733 231.512 214.955 1.00 65.19  ? 497 PHE B CZ  1 
ATOM   10059 N  N   . PRO B 1 498 ? 196.399 233.830 208.768 1.00 67.37  ? 498 PRO B N   1 
ATOM   10060 C  CA  . PRO B 1 498 ? 197.383 234.242 207.758 1.00 67.37  ? 498 PRO B CA  1 
ATOM   10061 C  C   . PRO B 1 498 ? 198.790 234.397 208.313 1.00 67.37  ? 498 PRO B C   1 
ATOM   10062 O  O   . PRO B 1 498 ? 199.186 235.503 208.690 1.00 67.37  ? 498 PRO B O   1 
ATOM   10063 C  CB  . PRO B 1 498 ? 196.835 235.589 207.264 1.00 67.37  ? 498 PRO B CB  1 
ATOM   10064 C  CG  . PRO B 1 498 ? 195.435 235.691 207.831 1.00 67.37  ? 498 PRO B CG  1 
ATOM   10065 C  CD  . PRO B 1 498 ? 195.480 234.922 209.105 1.00 67.37  ? 498 PRO B CD  1 
ATOM   10066 N  N   . LEU B 1 499 ? 199.551 233.308 208.376 1.00 66.24  ? 499 LEU B N   1 
ATOM   10067 C  CA  . LEU B 1 499 ? 200.932 233.376 208.832 1.00 66.24  ? 499 LEU B CA  1 
ATOM   10068 C  C   . LEU B 1 499 ? 201.812 234.017 207.755 1.00 66.24  ? 499 LEU B C   1 
ATOM   10069 O  O   . LEU B 1 499 ? 201.371 234.290 206.635 1.00 66.24  ? 499 LEU B O   1 
ATOM   10070 C  CB  . LEU B 1 499 ? 201.430 231.985 209.201 1.00 66.24  ? 499 LEU B CB  1 
ATOM   10071 C  CG  . LEU B 1 499 ? 200.528 231.235 210.180 1.00 66.24  ? 499 LEU B CG  1 
ATOM   10072 C  CD1 . LEU B 1 499 ? 201.134 229.892 210.542 1.00 66.24  ? 499 LEU B CD1 1 
ATOM   10073 C  CD2 . LEU B 1 499 ? 200.267 232.065 211.418 1.00 66.24  ? 499 LEU B CD2 1 
ATOM   10074 N  N   . THR B 1 500 ? 203.075 234.264 208.093 1.00 71.22  ? 500 THR B N   1 
ATOM   10075 C  CA  . THR B 1 500 ? 204.001 234.924 207.180 1.00 71.22  ? 500 THR B CA  1 
ATOM   10076 C  C   . THR B 1 500 ? 205.428 234.568 207.588 1.00 71.22  ? 500 THR B C   1 
ATOM   10077 O  O   . THR B 1 500 ? 205.665 234.030 208.673 1.00 71.22  ? 500 THR B O   1 
ATOM   10078 C  CB  . THR B 1 500 ? 203.780 236.438 207.171 1.00 71.22  ? 500 THR B CB  1 
ATOM   10079 O  OG1 . THR B 1 500 ? 204.549 237.027 206.117 1.00 71.22  ? 500 THR B OG1 1 
ATOM   10080 C  CG2 . THR B 1 500 ? 204.202 237.045 208.500 1.00 71.22  ? 500 THR B CG2 1 
ATOM   10081 N  N   . LEU B 1 501 ? 206.387 234.887 206.714 1.00 64.74  ? 501 LEU B N   1 
ATOM   10082 C  CA  . LEU B 1 501 ? 207.770 234.479 206.913 1.00 64.74  ? 501 LEU B CA  1 
ATOM   10083 C  C   . LEU B 1 501 ? 208.732 235.649 206.753 1.00 64.74  ? 501 LEU B C   1 
ATOM   10084 O  O   . LEU B 1 501 ? 208.528 236.548 205.930 1.00 64.74  ? 501 LEU B O   1 
ATOM   10085 C  CB  . LEU B 1 501 ? 208.168 233.368 205.939 1.00 64.74  ? 501 LEU B CB  1 
ATOM   10086 C  CG  . LEU B 1 501 ? 207.434 232.033 206.057 1.00 64.74  ? 501 LEU B CG  1 
ATOM   10087 C  CD1 . LEU B 1 501 ? 207.773 231.136 204.885 1.00 64.74  ? 501 LEU B CD1 1 
ATOM   10088 C  CD2 . LEU B 1 501 ? 207.777 231.345 207.355 1.00 64.74  ? 501 LEU B CD2 1 
ATOM   10089 N  N   . SER B 1 502 ? 209.798 235.613 207.554 1.00 69.73  ? 502 SER B N   1 
ATOM   10090 C  CA  . SER B 1 502 ? 210.942 236.506 207.415 1.00 69.73  ? 502 SER B CA  1 
ATOM   10091 C  C   . SER B 1 502 ? 212.173 235.644 207.183 1.00 69.73  ? 502 SER B C   1 
ATOM   10092 O  O   . SER B 1 502 ? 212.574 234.880 208.066 1.00 69.73  ? 502 SER B O   1 
ATOM   10093 C  CB  . SER B 1 502 ? 211.119 237.378 208.658 1.00 69.73  ? 502 SER B CB  1 
ATOM   10094 O  OG  . SER B 1 502 ? 210.027 238.264 208.812 1.00 69.73  ? 502 SER B OG  1 
ATOM   10095 N  N   . ILE B 1 503 ? 212.764 235.751 206.000 1.00 65.10  ? 503 ILE B N   1 
ATOM   10096 C  CA  . ILE B 1 503 ? 213.780 234.810 205.560 1.00 65.10  ? 503 ILE B CA  1 
ATOM   10097 C  C   . ILE B 1 503 ? 215.016 235.574 205.109 1.00 65.10  ? 503 ILE B C   1 
ATOM   10098 O  O   . ILE B 1 503 ? 214.922 236.534 204.334 1.00 65.10  ? 503 ILE B O   1 
ATOM   10099 C  CB  . ILE B 1 503 ? 213.240 233.880 204.454 1.00 65.10  ? 503 ILE B CB  1 
ATOM   10100 C  CG1 . ILE B 1 503 ? 214.368 233.103 203.777 1.00 65.10  ? 503 ILE B CG1 1 
ATOM   10101 C  CG2 . ILE B 1 503 ? 212.390 234.642 203.468 1.00 65.10  ? 503 ILE B CG2 1 
ATOM   10102 C  CD1 . ILE B 1 503 ? 213.874 232.047 202.819 1.00 65.10  ? 503 ILE B CD1 1 
ATOM   10103 N  N   . GLY B 1 504 ? 216.169 235.151 205.617 1.00 66.26  ? 504 GLY B N   1 
ATOM   10104 C  CA  . GLY B 1 504 ? 217.433 235.776 205.294 1.00 66.26  ? 504 GLY B CA  1 
ATOM   10105 C  C   . GLY B 1 504 ? 218.399 234.764 204.713 1.00 66.26  ? 504 GLY B C   1 
ATOM   10106 O  O   . GLY B 1 504 ? 218.382 233.585 205.074 1.00 66.26  ? 504 GLY B O   1 
ATOM   10107 N  N   . ILE B 1 505 ? 219.250 235.241 203.808 1.00 64.09  ? 505 ILE B N   1 
ATOM   10108 C  CA  . ILE B 1 505 ? 220.139 234.393 203.024 1.00 64.09  ? 505 ILE B CA  1 
ATOM   10109 C  C   . ILE B 1 505 ? 221.576 234.671 203.440 1.00 64.09  ? 505 ILE B C   1 
ATOM   10110 O  O   . ILE B 1 505 ? 221.974 235.833 203.583 1.00 64.09  ? 505 ILE B O   1 
ATOM   10111 C  CB  . ILE B 1 505 ? 219.953 234.636 201.517 1.00 64.09  ? 505 ILE B CB  1 
ATOM   10112 C  CG1 . ILE B 1 505 ? 218.469 234.704 201.153 1.00 64.09  ? 505 ILE B CG1 1 
ATOM   10113 C  CG2 . ILE B 1 505 ? 220.649 233.559 200.713 1.00 64.09  ? 505 ILE B CG2 1 
ATOM   10114 C  CD1 . ILE B 1 505 ? 217.659 233.517 201.617 1.00 64.09  ? 505 ILE B CD1 1 
ATOM   10115 N  N   . SER B 1 506 ? 222.356 233.611 203.626 1.00 64.18  ? 506 SER B N   1 
ATOM   10116 C  CA  . SER B 1 506 ? 223.768 233.743 203.939 1.00 64.18  ? 506 SER B CA  1 
ATOM   10117 C  C   . SER B 1 506 ? 224.579 232.831 203.036 1.00 64.18  ? 506 SER B C   1 
ATOM   10118 O  O   . SER B 1 506 ? 224.211 231.673 202.825 1.00 64.18  ? 506 SER B O   1 
ATOM   10119 C  CB  . SER B 1 506 ? 224.034 233.394 205.396 1.00 64.18  ? 506 SER B CB  1 
ATOM   10120 O  OG  . SER B 1 506 ? 223.519 232.111 205.690 1.00 64.18  ? 506 SER B OG  1 
ATOM   10121 N  N   . TYR B 1 507 ? 225.687 233.351 202.507 1.00 65.96  ? 507 TYR B N   1 
ATOM   10122 C  CA  . TYR B 1 507 ? 226.532 232.569 201.611 1.00 65.96  ? 507 TYR B CA  1 
ATOM   10123 C  C   . TYR B 1 507 ? 227.915 233.183 201.461 1.00 65.96  ? 507 TYR B C   1 
ATOM   10124 O  O   . TYR B 1 507 ? 228.040 234.358 201.110 1.00 65.96  ? 507 TYR B O   1 
ATOM   10125 C  CB  . TYR B 1 507 ? 225.875 232.437 200.237 1.00 65.96  ? 507 TYR B CB  1 
ATOM   10126 C  CG  . TYR B 1 507 ? 226.856 232.230 199.111 1.00 65.96  ? 507 TYR B CG  1 
ATOM   10127 C  CD1 . TYR B 1 507 ? 227.375 230.972 198.841 1.00 65.96  ? 507 TYR B CD1 1 
ATOM   10128 C  CD2 . TYR B 1 507 ? 227.260 233.289 198.311 1.00 65.96  ? 507 TYR B CD2 1 
ATOM   10129 C  CE1 . TYR B 1 507 ? 228.270 230.776 197.808 1.00 65.96  ? 507 TYR B CE1 1 
ATOM   10130 C  CE2 . TYR B 1 507 ? 228.157 233.104 197.279 1.00 65.96  ? 507 TYR B CE2 1 
ATOM   10131 C  CZ  . TYR B 1 507 ? 228.659 231.845 197.032 1.00 65.96  ? 507 TYR B CZ  1 
ATOM   10132 O  OH  . TYR B 1 507 ? 229.552 231.654 196.004 1.00 65.96  ? 507 TYR B OH  1 
ATOM   10133 N  N   . ASP B 1 508 ? 228.955 232.395 201.716 1.00 73.08  ? 508 ASP B N   1 
ATOM   10134 C  CA  . ASP B 1 508 ? 230.341 232.804 201.514 1.00 73.08  ? 508 ASP B CA  1 
ATOM   10135 C  C   . ASP B 1 508 ? 231.213 231.556 201.515 1.00 73.08  ? 508 ASP B C   1 
ATOM   10136 O  O   . ASP B 1 508 ? 230.792 230.484 201.958 1.00 73.08  ? 508 ASP B O   1 
ATOM   10137 C  CB  . ASP B 1 508 ? 230.823 233.788 202.586 1.00 73.08  ? 508 ASP B CB  1 
ATOM   10138 C  CG  . ASP B 1 508 ? 230.597 235.233 202.194 1.00 73.08  ? 508 ASP B CG  1 
ATOM   10139 O  OD1 . ASP B 1 508 ? 230.685 235.541 200.988 1.00 73.08  ? 508 ASP B OD1 1 
ATOM   10140 O  OD2 . ASP B 1 508 ? 230.332 236.060 203.088 1.00 73.08  ? 508 ASP B OD2 1 
ATOM   10141 N  N   . LEU B 1 509 ? 232.438 231.716 201.026 1.00 74.84  ? 509 LEU B N   1 
ATOM   10142 C  CA  . LEU B 1 509 ? 233.378 230.614 200.910 1.00 74.84  ? 509 LEU B CA  1 
ATOM   10143 C  C   . LEU B 1 509 ? 234.411 230.673 202.025 1.00 74.84  ? 509 LEU B C   1 
ATOM   10144 O  O   . LEU B 1 509 ? 234.854 231.750 202.433 1.00 74.84  ? 509 LEU B O   1 
ATOM   10145 C  CB  . LEU B 1 509 ? 234.094 230.647 199.557 1.00 74.84  ? 509 LEU B CB  1 
ATOM   10146 C  CG  . LEU B 1 509 ? 233.374 230.135 198.308 1.00 74.84  ? 509 LEU B CG  1 
ATOM   10147 C  CD1 . LEU B 1 509 ? 232.349 231.144 197.808 1.00 74.84  ? 509 LEU B CD1 1 
ATOM   10148 C  CD2 . LEU B 1 509 ? 234.377 229.798 197.216 1.00 74.84  ? 509 LEU B CD2 1 
ATOM   10149 N  N   . GLY B 1 510 ? 234.780 229.498 202.529 1.00 81.67  ? 510 GLY B N   1 
ATOM   10150 C  CA  . GLY B 1 510 ? 235.884 229.377 203.462 1.00 81.67  ? 510 GLY B CA  1 
ATOM   10151 C  C   . GLY B 1 510 ? 235.596 229.850 204.872 1.00 81.67  ? 510 GLY B C   1 
ATOM   10152 O  O   . GLY B 1 510 ? 236.273 229.437 205.818 1.00 81.67  ? 510 GLY B O   1 
ATOM   10153 N  N   . LYS B 1 511 ? 234.601 230.718 205.028 1.00 78.69  ? 511 LYS B N   1 
ATOM   10154 C  CA  . LYS B 1 511 ? 234.286 231.266 206.338 1.00 78.69  ? 511 LYS B CA  1 
ATOM   10155 C  C   . LYS B 1 511 ? 233.708 230.188 207.245 1.00 78.69  ? 511 LYS B C   1 
ATOM   10156 O  O   . LYS B 1 511 ? 232.986 229.295 206.795 1.00 78.69  ? 511 LYS B O   1 
ATOM   10157 C  CB  . LYS B 1 511 ? 233.300 232.425 206.205 1.00 78.69  ? 511 LYS B CB  1 
ATOM   10158 C  CG  . LYS B 1 511 ? 233.718 233.481 205.193 1.00 78.69  ? 511 LYS B CG  1 
ATOM   10159 C  CD  . LYS B 1 511 ? 235.109 234.017 205.492 1.00 78.69  ? 511 LYS B CD  1 
ATOM   10160 C  CE  . LYS B 1 511 ? 235.122 234.849 206.764 1.00 78.69  ? 511 LYS B CE  1 
ATOM   10161 N  NZ  . LYS B 1 511 ? 234.465 236.171 206.571 1.00 78.69  ? 511 LYS B NZ  1 
ATOM   10162 N  N   . ASN B 1 512 ? 234.038 230.274 208.532 1.00 77.01  ? 512 ASN B N   1 
ATOM   10163 C  CA  . ASN B 1 512 ? 233.486 229.348 209.509 1.00 77.01  ? 512 ASN B CA  1 
ATOM   10164 C  C   . ASN B 1 512 ? 231.981 229.539 209.617 1.00 77.01  ? 512 ASN B C   1 
ATOM   10165 O  O   . ASN B 1 512 ? 231.451 230.623 209.359 1.00 77.01  ? 512 ASN B O   1 
ATOM   10166 C  CB  . ASN B 1 512 ? 234.141 229.557 210.873 1.00 77.01  ? 512 ASN B CB  1 
ATOM   10167 C  CG  . ASN B 1 512 ? 234.024 230.987 211.360 1.00 77.01  ? 512 ASN B CG  1 
ATOM   10168 O  OD1 . ASN B 1 512 ? 232.937 231.453 211.698 1.00 77.01  ? 512 ASN B OD1 1 
ATOM   10169 N  ND2 . ASN B 1 512 ? 235.149 231.692 211.397 1.00 77.01  ? 512 ASN B ND2 1 
ATOM   10170 N  N   . ARG B 1 513 ? 231.286 228.468 210.002 1.00 72.35  ? 513 ARG B N   1 
ATOM   10171 C  CA  . ARG B 1 513 ? 229.830 228.507 209.994 1.00 72.35  ? 513 ARG B CA  1 
ATOM   10172 C  C   . ARG B 1 513 ? 229.276 229.546 210.953 1.00 72.35  ? 513 ARG B C   1 
ATOM   10173 O  O   . ARG B 1 513 ? 228.131 229.978 210.783 1.00 72.35  ? 513 ARG B O   1 
ATOM   10174 C  CB  . ARG B 1 513 ? 229.255 227.128 210.319 1.00 72.35  ? 513 ARG B CB  1 
ATOM   10175 C  CG  . ARG B 1 513 ? 229.322 226.716 211.775 1.00 72.35  ? 513 ARG B CG  1 
ATOM   10176 C  CD  . ARG B 1 513 ? 228.405 225.528 212.014 1.00 72.35  ? 513 ARG B CD  1 
ATOM   10177 N  NE  . ARG B 1 513 ? 228.699 224.824 213.255 1.00 72.35  ? 513 ARG B NE  1 
ATOM   10178 C  CZ  . ARG B 1 513 ? 228.122 225.086 214.418 1.00 72.35  ? 513 ARG B CZ  1 
ATOM   10179 N  NH1 . ARG B 1 513 ? 227.236 226.060 214.545 1.00 72.35  ? 513 ARG B NH1 1 
ATOM   10180 N  NH2 . ARG B 1 513 ? 228.442 224.355 215.481 1.00 72.35  ? 513 ARG B NH2 1 
ATOM   10181 N  N   . ASP B 1 514 ? 230.060 229.965 211.947 1.00 74.94  ? 514 ASP B N   1 
ATOM   10182 C  CA  . ASP B 1 514 ? 229.610 231.034 212.828 1.00 74.94  ? 514 ASP B CA  1 
ATOM   10183 C  C   . ASP B 1 514 ? 229.389 232.324 212.050 1.00 74.94  ? 514 ASP B C   1 
ATOM   10184 O  O   . ASP B 1 514 ? 228.402 233.031 212.276 1.00 74.94  ? 514 ASP B O   1 
ATOM   10185 C  CB  . ASP B 1 514 ? 230.618 231.246 213.956 1.00 74.94  ? 514 ASP B CB  1 
ATOM   10186 C  CG  . ASP B 1 514 ? 230.639 230.095 214.940 1.00 74.94  ? 514 ASP B CG  1 
ATOM   10187 O  OD1 . ASP B 1 514 ? 229.686 229.288 214.930 1.00 74.94  ? 514 ASP B OD1 1 
ATOM   10188 O  OD2 . ASP B 1 514 ? 231.607 229.997 215.724 1.00 74.94  ? 514 ASP B OD2 1 
ATOM   10189 N  N   . TYR B 1 515 ? 230.289 232.637 211.117 1.00 75.56  ? 515 TYR B N   1 
ATOM   10190 C  CA  . TYR B 1 515 ? 230.135 233.835 210.299 1.00 75.56  ? 515 TYR B CA  1 
ATOM   10191 C  C   . TYR B 1 515 ? 228.823 233.803 209.524 1.00 75.56  ? 515 TYR B C   1 
ATOM   10192 O  O   . TYR B 1 515 ? 228.031 234.754 209.575 1.00 75.56  ? 515 TYR B O   1 
ATOM   10193 C  CB  . TYR B 1 515 ? 231.324 233.956 209.348 1.00 75.56  ? 515 TYR B CB  1 
ATOM   10194 C  CG  . TYR B 1 515 ? 231.265 235.136 208.412 1.00 75.56  ? 515 TYR B CG  1 
ATOM   10195 C  CD1 . TYR B 1 515 ? 231.623 236.405 208.841 1.00 75.56  ? 515 TYR B CD1 1 
ATOM   10196 C  CD2 . TYR B 1 515 ? 230.859 234.982 207.097 1.00 75.56  ? 515 TYR B CD2 1 
ATOM   10197 C  CE1 . TYR B 1 515 ? 231.574 237.488 207.986 1.00 75.56  ? 515 TYR B CE1 1 
ATOM   10198 C  CE2 . TYR B 1 515 ? 230.806 236.058 206.234 1.00 75.56  ? 515 TYR B CE2 1 
ATOM   10199 C  CZ  . TYR B 1 515 ? 231.165 237.308 206.683 1.00 75.56  ? 515 TYR B CZ  1 
ATOM   10200 O  OH  . TYR B 1 515 ? 231.112 238.383 205.826 1.00 75.56  ? 515 TYR B OH  1 
ATOM   10201 N  N   . LEU B 1 516 ? 228.572 232.705 208.811 1.00 72.78  ? 516 LEU B N   1 
ATOM   10202 C  CA  . LEU B 1 516 ? 227.375 232.608 207.984 1.00 72.78  ? 516 LEU B CA  1 
ATOM   10203 C  C   . LEU B 1 516 ? 226.112 232.624 208.834 1.00 72.78  ? 516 LEU B C   1 
ATOM   10204 O  O   . LEU B 1 516 ? 225.140 233.321 208.508 1.00 72.78  ? 516 LEU B O   1 
ATOM   10205 C  CB  . LEU B 1 516 ? 227.438 231.342 207.133 1.00 72.78  ? 516 LEU B CB  1 
ATOM   10206 C  CG  . LEU B 1 516 ? 228.567 231.298 206.104 1.00 72.78  ? 516 LEU B CG  1 
ATOM   10207 C  CD1 . LEU B 1 516 ? 228.591 229.957 205.386 1.00 72.78  ? 516 LEU B CD1 1 
ATOM   10208 C  CD2 . LEU B 1 516 ? 228.429 232.441 205.111 1.00 72.78  ? 516 LEU B CD2 1 
ATOM   10209 N  N   . LEU B 1 517 ? 226.105 231.864 209.931 1.00 72.57  ? 517 LEU B N   1 
ATOM   10210 C  CA  . LEU B 1 517 ? 224.933 231.837 210.796 1.00 72.57  ? 517 LEU B CA  1 
ATOM   10211 C  C   . LEU B 1 517 ? 224.655 233.215 211.382 1.00 72.57  ? 517 LEU B C   1 
ATOM   10212 O  O   . LEU B 1 517 ? 223.499 233.654 211.441 1.00 72.57  ? 517 LEU B O   1 
ATOM   10213 C  CB  . LEU B 1 517 ? 225.130 230.807 211.908 1.00 72.57  ? 517 LEU B CB  1 
ATOM   10214 C  CG  . LEU B 1 517 ? 224.556 229.402 211.700 1.00 72.57  ? 517 LEU B CG  1 
ATOM   10215 C  CD1 . LEU B 1 517 ? 223.041 229.430 211.705 1.00 72.57  ? 517 LEU B CD1 1 
ATOM   10216 C  CD2 . LEU B 1 517 ? 225.072 228.786 210.411 1.00 72.57  ? 517 LEU B CD2 1 
ATOM   10217 N  N   . SER B 1 518 ? 225.703 233.916 211.810 1.00 73.24  ? 518 SER B N   1 
ATOM   10218 C  CA  . SER B 1 518 ? 225.523 235.248 212.365 1.00 73.24  ? 518 SER B CA  1 
ATOM   10219 C  C   . SER B 1 518 ? 224.959 236.199 211.323 1.00 73.24  ? 518 SER B C   1 
ATOM   10220 O  O   . SER B 1 518 ? 224.066 236.997 211.621 1.00 73.24  ? 518 SER B O   1 
ATOM   10221 C  CB  . SER B 1 518 ? 226.854 235.769 212.907 1.00 73.24  ? 518 SER B CB  1 
ATOM   10222 O  OG  . SER B 1 518 ? 227.853 235.747 211.903 1.00 73.24  ? 518 SER B OG  1 
ATOM   10223 N  N   . THR B 1 519 ? 225.478 236.138 210.094 1.00 70.33  ? 519 THR B N   1 
ATOM   10224 C  CA  . THR B 1 519 ? 224.981 237.040 209.059 1.00 70.33  ? 519 THR B CA  1 
ATOM   10225 C  C   . THR B 1 519 ? 223.513 236.774 208.767 1.00 70.33  ? 519 THR B C   1 
ATOM   10226 O  O   . THR B 1 519 ? 222.714 237.710 208.619 1.00 70.33  ? 519 THR B O   1 
ATOM   10227 C  CB  . THR B 1 519 ? 225.808 236.895 207.788 1.00 70.33  ? 519 THR B CB  1 
ATOM   10228 O  OG1 . THR B 1 519 ? 225.850 235.516 207.406 1.00 70.33  ? 519 THR B OG1 1 
ATOM   10229 C  CG2 . THR B 1 519 ? 227.215 237.383 208.027 1.00 70.33  ? 519 THR B CG2 1 
ATOM   10230 N  N   . ALA B 1 520 ? 223.137 235.499 208.688 1.00 71.19  ? 520 ALA B N   1 
ATOM   10231 C  CA  . ALA B 1 520 ? 221.746 235.163 208.424 1.00 71.19  ? 520 ALA B CA  1 
ATOM   10232 C  C   . ALA B 1 520 ? 220.846 235.654 209.548 1.00 71.19  ? 520 ALA B C   1 
ATOM   10233 O  O   . ALA B 1 520 ? 219.769 236.211 209.304 1.00 71.19  ? 520 ALA B O   1 
ATOM   10234 C  CB  . ALA B 1 520 ? 221.606 233.656 208.226 1.00 71.19  ? 520 ALA B CB  1 
ATOM   10235 N  N   . HIS B 1 521 ? 221.278 235.468 210.798 1.00 76.80  ? 521 HIS B N   1 
ATOM   10236 C  CA  . HIS B 1 521 ? 220.474 235.937 211.922 1.00 76.80  ? 521 HIS B CA  1 
ATOM   10237 C  C   . HIS B 1 521 ? 220.374 237.456 211.942 1.00 76.80  ? 521 HIS B C   1 
ATOM   10238 O  O   . HIS B 1 521 ? 219.337 238.004 212.326 1.00 76.80  ? 521 HIS B O   1 
ATOM   10239 C  CB  . HIS B 1 521 ? 221.052 235.425 213.240 1.00 76.80  ? 521 HIS B CB  1 
ATOM   10240 C  CG  . HIS B 1 521 ? 220.213 235.756 214.434 1.00 76.80  ? 521 HIS B CG  1 
ATOM   10241 N  ND1 . HIS B 1 521 ? 220.749 235.985 215.682 1.00 76.80  ? 521 HIS B ND1 1 
ATOM   10242 C  CD2 . HIS B 1 521 ? 218.873 235.901 214.568 1.00 76.80  ? 521 HIS B CD2 1 
ATOM   10243 C  CE1 . HIS B 1 521 ? 219.776 236.255 216.535 1.00 76.80  ? 521 HIS B CE1 1 
ATOM   10244 N  NE2 . HIS B 1 521 ? 218.628 236.210 215.884 1.00 76.80  ? 521 HIS B NE2 1 
ATOM   10245 N  N   . ASN B 1 522 ? 221.440 238.149 211.544 1.00 73.54  ? 522 ASN B N   1 
ATOM   10246 C  CA  . ASN B 1 522 ? 221.386 239.601 211.446 1.00 73.54  ? 522 ASN B CA  1 
ATOM   10247 C  C   . ASN B 1 522 ? 220.356 240.029 210.414 1.00 73.54  ? 522 ASN B C   1 
ATOM   10248 O  O   . ASN B 1 522 ? 219.587 240.972 210.636 1.00 73.54  ? 522 ASN B O   1 
ATOM   10249 C  CB  . ASN B 1 522 ? 222.768 240.147 211.089 1.00 73.54  ? 522 ASN B CB  1 
ATOM   10250 C  CG  . ASN B 1 522 ? 222.865 241.646 211.267 1.00 73.54  ? 522 ASN B CG  1 
ATOM   10251 O  OD1 . ASN B 1 522 ? 221.913 242.297 211.697 1.00 73.54  ? 522 ASN B OD1 1 
ATOM   10252 N  ND2 . ASN B 1 522 ? 224.022 242.206 210.935 1.00 73.54  ? 522 ASN B ND2 1 
ATOM   10253 N  N   . ALA B 1 523 ? 220.326 239.341 209.273 1.00 73.50  ? 523 ALA B N   1 
ATOM   10254 C  CA  . ALA B 1 523 ? 219.318 239.650 208.264 1.00 73.50  ? 523 ALA B CA  1 
ATOM   10255 C  C   . ALA B 1 523 ? 217.914 239.389 208.796 1.00 73.50  ? 523 ALA B C   1 
ATOM   10256 O  O   . ALA B 1 523 ? 216.994 240.186 208.569 1.00 73.50  ? 523 ALA B O   1 
ATOM   10257 C  CB  . ALA B 1 523 ? 219.576 238.835 206.999 1.00 73.50  ? 523 ALA B CB  1 
ATOM   10258 N  N   . MET B 1 524 ? 217.734 238.273 209.504 1.00 75.61  ? 524 MET B N   1 
ATOM   10259 C  CA  . MET B 1 524 ? 216.437 237.958 210.096 1.00 75.61  ? 524 MET B CA  1 
ATOM   10260 C  C   . MET B 1 524 ? 215.996 239.046 211.063 1.00 75.61  ? 524 MET B C   1 
ATOM   10261 O  O   . MET B 1 524 ? 214.843 239.492 211.038 1.00 75.61  ? 524 MET B O   1 
ATOM   10262 C  CB  . MET B 1 524 ? 216.499 236.616 210.823 1.00 75.61  ? 524 MET B CB  1 
ATOM   10263 C  CG  . MET B 1 524 ? 216.357 235.397 209.946 1.00 75.61  ? 524 MET B CG  1 
ATOM   10264 S  SD  . MET B 1 524 ? 216.048 233.947 210.970 1.00 75.61  ? 524 MET B SD  1 
ATOM   10265 C  CE  . MET B 1 524 ? 214.455 234.368 211.668 1.00 75.61  ? 524 MET B CE  1 
ATOM   10266 N  N   . ASP B 1 525 ? 216.906 239.471 211.940 1.00 76.40  ? 525 ASP B N   1 
ATOM   10267 C  CA  . ASP B 1 525 ? 216.574 240.506 212.909 1.00 76.40  ? 525 ASP B CA  1 
ATOM   10268 C  C   . ASP B 1 525 ? 216.233 241.811 212.209 1.00 76.40  ? 525 ASP B C   1 
ATOM   10269 O  O   . ASP B 1 525 ? 215.278 242.497 212.592 1.00 76.40  ? 525 ASP B O   1 
ATOM   10270 C  CB  . ASP B 1 525 ? 217.733 240.701 213.885 1.00 76.40  ? 525 ASP B CB  1 
ATOM   10271 C  CG  . ASP B 1 525 ? 217.956 239.492 214.769 1.00 76.40  ? 525 ASP B CG  1 
ATOM   10272 O  OD1 . ASP B 1 525 ? 216.978 238.764 215.040 1.00 76.40  ? 525 ASP B OD1 1 
ATOM   10273 O  OD2 . ASP B 1 525 ? 219.109 239.268 215.195 1.00 76.40  ? 525 ASP B OD2 1 
ATOM   10274 N  N   . TYR B 1 526 ? 216.991 242.162 211.169 1.00 72.67  ? 526 TYR B N   1 
ATOM   10275 C  CA  . TYR B 1 526 ? 216.707 243.387 210.436 1.00 72.67  ? 526 TYR B CA  1 
ATOM   10276 C  C   . TYR B 1 526 ? 215.315 243.350 209.824 1.00 72.67  ? 526 TYR B C   1 
ATOM   10277 O  O   . TYR B 1 526 ? 214.540 244.300 209.967 1.00 72.67  ? 526 TYR B O   1 
ATOM   10278 C  CB  . TYR B 1 526 ? 217.757 243.608 209.354 1.00 72.67  ? 526 TYR B CB  1 
ATOM   10279 C  CG  . TYR B 1 526 ? 217.713 244.987 208.748 1.00 72.67  ? 526 TYR B CG  1 
ATOM   10280 C  CD1 . TYR B 1 526 ? 217.102 246.037 209.410 1.00 72.67  ? 526 TYR B CD1 1 
ATOM   10281 C  CD2 . TYR B 1 526 ? 218.283 245.237 207.507 1.00 72.67  ? 526 TYR B CD2 1 
ATOM   10282 C  CE1 . TYR B 1 526 ? 217.062 247.301 208.861 1.00 72.67  ? 526 TYR B CE1 1 
ATOM   10283 C  CE2 . TYR B 1 526 ? 218.246 246.498 206.946 1.00 72.67  ? 526 TYR B CE2 1 
ATOM   10284 C  CZ  . TYR B 1 526 ? 217.633 247.526 207.627 1.00 72.67  ? 526 TYR B CZ  1 
ATOM   10285 O  OH  . TYR B 1 526 ? 217.594 248.785 207.073 1.00 72.67  ? 526 TYR B OH  1 
ATOM   10286 N  N   . ILE B 1 527 ? 214.972 242.253 209.147 1.00 73.80  ? 527 ILE B N   1 
ATOM   10287 C  CA  . ILE B 1 527 ? 213.682 242.209 208.465 1.00 73.80  ? 527 ILE B CA  1 
ATOM   10288 C  C   . ILE B 1 527 ? 212.538 242.162 209.472 1.00 73.80  ? 527 ILE B C   1 
ATOM   10289 O  O   . ILE B 1 527 ? 211.489 242.788 209.267 1.00 73.80  ? 527 ILE B O   1 
ATOM   10290 C  CB  . ILE B 1 527 ? 213.627 241.036 207.467 1.00 73.80  ? 527 ILE B CB  1 
ATOM   10291 C  CG1 . ILE B 1 527 ? 212.290 241.030 206.722 1.00 73.80  ? 527 ILE B CG1 1 
ATOM   10292 C  CG2 . ILE B 1 527 ? 213.851 239.708 208.157 1.00 73.80  ? 527 ILE B CG2 1 
ATOM   10293 C  CD1 . ILE B 1 527 ? 212.022 242.295 205.935 1.00 73.80  ? 527 ILE B CD1 1 
ATOM   10294 N  N   . ARG B 1 528 ? 212.718 241.444 210.585 1.00 74.83  ? 528 ARG B N   1 
ATOM   10295 C  CA  . ARG B 1 528 ? 211.649 241.370 211.576 1.00 74.83  ? 528 ARG B CA  1 
ATOM   10296 C  C   . ARG B 1 528 ? 211.448 242.709 212.273 1.00 74.83  ? 528 ARG B C   1 
ATOM   10297 O  O   . ARG B 1 528 ? 210.313 243.082 212.592 1.00 74.83  ? 528 ARG B O   1 
ATOM   10298 C  CB  . ARG B 1 528 ? 211.941 240.265 212.587 1.00 74.83  ? 528 ARG B CB  1 
ATOM   10299 C  CG  . ARG B 1 528 ? 211.786 238.875 212.004 1.00 74.83  ? 528 ARG B CG  1 
ATOM   10300 C  CD  . ARG B 1 528 ? 211.184 237.901 213.002 1.00 74.83  ? 528 ARG B CD  1 
ATOM   10301 N  NE  . ARG B 1 528 ? 212.052 237.675 214.151 1.00 74.83  ? 528 ARG B NE  1 
ATOM   10302 C  CZ  . ARG B 1 528 ? 211.837 236.753 215.079 1.00 74.83  ? 528 ARG B CZ  1 
ATOM   10303 N  NH1 . ARG B 1 528 ? 210.793 235.943 215.018 1.00 74.83  ? 528 ARG B NH1 1 
ATOM   10304 N  NH2 . ARG B 1 528 ? 212.692 236.639 216.091 1.00 74.83  ? 528 ARG B NH2 1 
ATOM   10305 N  N   . LYS B 1 529 ? 212.532 243.448 212.519 1.00 74.77  ? 529 LYS B N   1 
ATOM   10306 C  CA  . LYS B 1 529 ? 212.393 244.795 213.057 1.00 74.77  ? 529 LYS B CA  1 
ATOM   10307 C  C   . LYS B 1 529 ? 211.743 245.729 212.047 1.00 74.77  ? 529 LYS B C   1 
ATOM   10308 O  O   . LYS B 1 529 ? 210.961 246.607 212.427 1.00 74.77  ? 529 LYS B O   1 
ATOM   10309 C  CB  . LYS B 1 529 ? 213.758 245.334 213.484 1.00 74.77  ? 529 LYS B CB  1 
ATOM   10310 C  CG  . LYS B 1 529 ? 213.699 246.589 214.342 1.00 74.77  ? 529 LYS B CG  1 
ATOM   10311 C  CD  . LYS B 1 529 ? 213.977 247.839 213.522 1.00 74.77  ? 529 LYS B CD  1 
ATOM   10312 C  CE  . LYS B 1 529 ? 213.973 249.085 214.393 1.00 74.77  ? 529 LYS B CE  1 
ATOM   10313 N  NZ  . LYS B 1 529 ? 214.203 250.321 213.595 1.00 74.77  ? 529 LYS B NZ  1 
ATOM   10314 N  N   . ASN B 1 530 ? 212.056 245.562 210.762 1.00 72.47  ? 530 ASN B N   1 
ATOM   10315 C  CA  . ASN B 1 530 ? 211.430 246.382 209.735 1.00 72.47  ? 530 ASN B CA  1 
ATOM   10316 C  C   . ASN B 1 530 ? 209.953 246.065 209.567 1.00 72.47  ? 530 ASN B C   1 
ATOM   10317 O  O   . ASN B 1 530 ? 209.198 246.926 209.104 1.00 72.47  ? 530 ASN B O   1 
ATOM   10318 C  CB  . ASN B 1 530 ? 212.155 246.202 208.403 1.00 72.47  ? 530 ASN B CB  1 
ATOM   10319 C  CG  . ASN B 1 530 ? 213.614 246.591 208.481 1.00 72.47  ? 530 ASN B CG  1 
ATOM   10320 O  OD1 . ASN B 1 530 ? 214.004 247.408 209.313 1.00 72.47  ? 530 ASN B OD1 1 
ATOM   10321 N  ND2 . ASN B 1 530 ? 214.432 245.999 207.620 1.00 72.47  ? 530 ASN B ND2 1 
ATOM   10322 N  N   . GLY B 1 531 ? 209.523 244.858 209.925 1.00 74.80  ? 531 GLY B N   1 
ATOM   10323 C  CA  . GLY B 1 531 ? 208.108 244.545 209.878 1.00 74.80  ? 531 GLY B CA  1 
ATOM   10324 C  C   . GLY B 1 531 ? 207.768 243.146 209.407 1.00 74.80  ? 531 GLY B C   1 
ATOM   10325 O  O   . GLY B 1 531 ? 206.593 242.767 209.371 1.00 74.80  ? 531 GLY B O   1 
ATOM   10326 N  N   . GLY B 1 532 ? 208.779 242.371 209.036 1.00 71.78  ? 532 GLY B N   1 
ATOM   10327 C  CA  . GLY B 1 532 ? 208.537 241.004 208.634 1.00 71.78  ? 532 GLY B CA  1 
ATOM   10328 C  C   . GLY B 1 532 ? 207.925 240.895 207.247 1.00 71.78  ? 532 GLY B C   1 
ATOM   10329 O  O   . GLY B 1 532 ? 207.782 241.870 206.508 1.00 71.78  ? 532 GLY B O   1 
ATOM   10330 N  N   . ASN B 1 533 ? 207.557 239.657 206.907 1.00 68.30  ? 533 ASN B N   1 
ATOM   10331 C  CA  . ASN B 1 533 ? 206.963 239.326 205.609 1.00 68.30  ? 533 ASN B CA  1 
ATOM   10332 C  C   . ASN B 1 533 ? 207.908 239.689 204.464 1.00 68.30  ? 533 ASN B C   1 
ATOM   10333 O  O   . ASN B 1 533 ? 207.598 240.528 203.620 1.00 68.30  ? 533 ASN B O   1 
ATOM   10334 C  CB  . ASN B 1 533 ? 205.604 240.009 205.433 1.00 68.30  ? 533 ASN B CB  1 
ATOM   10335 C  CG  . ASN B 1 533 ? 204.816 239.446 204.275 1.00 68.30  ? 533 ASN B CG  1 
ATOM   10336 O  OD1 . ASN B 1 533 ? 204.429 238.278 204.282 1.00 68.30  ? 533 ASN B OD1 1 
ATOM   10337 N  ND2 . ASN B 1 533 ? 204.574 240.273 203.267 1.00 68.30  ? 533 ASN B ND2 1 
ATOM   10338 N  N   . GLY B 1 534 ? 209.066 239.042 204.437 1.00 63.49  ? 534 GLY B N   1 
ATOM   10339 C  CA  . GLY B 1 534 ? 210.035 239.392 203.419 1.00 63.49  ? 534 GLY B CA  1 
ATOM   10340 C  C   . GLY B 1 534 ? 211.293 238.556 203.495 1.00 63.49  ? 534 GLY B C   1 
ATOM   10341 O  O   . GLY B 1 534 ? 211.405 237.635 204.302 1.00 63.49  ? 534 GLY B O   1 
ATOM   10342 N  N   . TRP B 1 535 ? 212.243 238.903 202.630 1.00 61.62  ? 535 TRP B N   1 
ATOM   10343 C  CA  . TRP B 1 535 ? 213.485 238.164 202.481 1.00 61.62  ? 535 TRP B CA  1 
ATOM   10344 C  C   . TRP B 1 535 ? 214.609 239.139 202.169 1.00 61.62  ? 535 TRP B C   1 
ATOM   10345 O  O   . TRP B 1 535 ? 214.400 240.138 201.476 1.00 61.62  ? 535 TRP B O   1 
ATOM   10346 C  CB  . TRP B 1 535 ? 213.381 237.122 201.367 1.00 61.62  ? 535 TRP B CB  1 
ATOM   10347 C  CG  . TRP B 1 535 ? 213.342 237.718 200.002 1.00 61.62  ? 535 TRP B CG  1 
ATOM   10348 C  CD1 . TRP B 1 535 ? 212.394 238.554 199.501 1.00 61.62  ? 535 TRP B CD1 1 
ATOM   10349 C  CD2 . TRP B 1 535 ? 214.308 237.538 198.969 1.00 61.62  ? 535 TRP B CD2 1 
ATOM   10350 N  NE1 . TRP B 1 535 ? 212.703 238.900 198.213 1.00 61.62  ? 535 TRP B NE1 1 
ATOM   10351 C  CE2 . TRP B 1 535 ? 213.877 238.290 197.862 1.00 61.62  ? 535 TRP B CE2 1 
ATOM   10352 C  CE3 . TRP B 1 535 ? 215.498 236.816 198.873 1.00 61.62  ? 535 TRP B CE3 1 
ATOM   10353 C  CZ2 . TRP B 1 535 ? 214.592 238.336 196.670 1.00 61.62  ? 535 TRP B CZ2 1 
ATOM   10354 C  CZ3 . TRP B 1 535 ? 216.201 236.858 197.696 1.00 61.62  ? 535 TRP B CZ3 1 
ATOM   10355 C  CH2 . TRP B 1 535 ? 215.750 237.614 196.607 1.00 61.62  ? 535 TRP B CH2 1 
ATOM   10356 N  N   . GLN B 1 536 ? 215.806 238.836 202.673 1.00 66.14  ? 536 GLN B N   1 
ATOM   10357 C  CA  . GLN B 1 536 ? 216.919 239.765 202.496 1.00 66.14  ? 536 GLN B CA  1 
ATOM   10358 C  C   . GLN B 1 536 ? 218.250 239.031 202.449 1.00 66.14  ? 536 GLN B C   1 
ATOM   10359 O  O   . GLN B 1 536 ? 218.389 237.917 202.961 1.00 66.14  ? 536 GLN B O   1 
ATOM   10360 C  CB  . GLN B 1 536 ? 216.959 240.817 203.610 1.00 66.14  ? 536 GLN B CB  1 
ATOM   10361 C  CG  . GLN B 1 536 ? 215.852 241.871 203.569 1.00 66.14  ? 536 GLN B CG  1 
ATOM   10362 C  CD  . GLN B 1 536 ? 215.998 242.865 202.431 1.00 66.14  ? 536 GLN B CD  1 
ATOM   10363 O  OE1 . GLN B 1 536 ? 216.282 242.496 201.293 1.00 66.14  ? 536 GLN B OE1 1 
ATOM   10364 N  NE2 . GLN B 1 536 ? 215.798 244.141 202.739 1.00 66.14  ? 536 GLN B NE2 1 
ATOM   10365 N  N   . PHE B 1 537 ? 219.231 239.698 201.840 1.00 69.86  ? 537 PHE B N   1 
ATOM   10366 C  CA  . PHE B 1 537 ? 220.625 239.275 201.817 1.00 69.86  ? 537 PHE B CA  1 
ATOM   10367 C  C   . PHE B 1 537 ? 221.423 240.070 202.838 1.00 69.86  ? 537 PHE B C   1 
ATOM   10368 O  O   . PHE B 1 537 ? 221.088 241.213 203.158 1.00 69.86  ? 537 PHE B O   1 
ATOM   10369 C  CB  . PHE B 1 537 ? 221.270 239.488 200.444 1.00 69.86  ? 537 PHE B CB  1 
ATOM   10370 C  CG  . PHE B 1 537 ? 220.638 238.712 199.324 1.00 69.86  ? 537 PHE B CG  1 
ATOM   10371 C  CD1 . PHE B 1 537 ? 219.549 239.219 198.639 1.00 69.86  ? 537 PHE B CD1 1 
ATOM   10372 C  CD2 . PHE B 1 537 ? 221.158 237.490 198.935 1.00 69.86  ? 537 PHE B CD2 1 
ATOM   10373 C  CE1 . PHE B 1 537 ? 218.983 238.516 197.598 1.00 69.86  ? 537 PHE B CE1 1 
ATOM   10374 C  CE2 . PHE B 1 537 ? 220.592 236.780 197.899 1.00 69.86  ? 537 PHE B CE2 1 
ATOM   10375 C  CZ  . PHE B 1 537 ? 219.502 237.294 197.229 1.00 69.86  ? 537 PHE B CZ  1 
ATOM   10376 N  N   . PHE B 1 538 ? 222.509 239.469 203.321 1.00 78.36  ? 538 PHE B N   1 
ATOM   10377 C  CA  . PHE B 1 538 ? 223.367 240.156 204.281 1.00 78.36  ? 538 PHE B CA  1 
ATOM   10378 C  C   . PHE B 1 538 ? 224.342 241.098 203.584 1.00 78.36  ? 538 PHE B C   1 
ATOM   10379 O  O   . PHE B 1 538 ? 224.319 242.312 203.812 1.00 78.36  ? 538 PHE B O   1 
ATOM   10380 C  CB  . PHE B 1 538 ? 224.131 239.141 205.135 1.00 78.36  ? 538 PHE B CB  1 
ATOM   10381 C  CG  . PHE B 1 538 ? 225.191 239.759 206.005 1.00 78.36  ? 538 PHE B CG  1 
ATOM   10382 C  CD1 . PHE B 1 538 ? 224.869 240.294 207.241 1.00 78.36  ? 538 PHE B CD1 1 
ATOM   10383 C  CD2 . PHE B 1 538 ? 226.512 239.805 205.585 1.00 78.36  ? 538 PHE B CD2 1 
ATOM   10384 C  CE1 . PHE B 1 538 ? 225.843 240.862 208.041 1.00 78.36  ? 538 PHE B CE1 1 
ATOM   10385 C  CE2 . PHE B 1 538 ? 227.489 240.375 206.377 1.00 78.36  ? 538 PHE B CE2 1 
ATOM   10386 C  CZ  . PHE B 1 538 ? 227.154 240.902 207.608 1.00 78.36  ? 538 PHE B CZ  1 
ATOM   10387 N  N   . SER B 1 539 ? 225.212 240.550 202.730 1.00 69.51  ? 539 SER B N   1 
ATOM   10388 C  CA  . SER B 1 539 ? 226.271 241.328 202.104 1.00 69.51  ? 539 SER B CA  1 
ATOM   10389 C  C   . SER B 1 539 ? 225.685 242.306 201.094 1.00 69.51  ? 539 SER B C   1 
ATOM   10390 O  O   . SER B 1 539 ? 225.017 241.890 200.137 1.00 69.51  ? 539 SER B O   1 
ATOM   10391 C  CB  . SER B 1 539 ? 227.280 240.404 201.425 1.00 69.51  ? 539 SER B CB  1 
ATOM   10392 O  OG  . SER B 1 539 ? 228.308 241.153 200.807 1.00 69.51  ? 539 SER B OG  1 
ATOM   10393 N  N   . PRO B 1 540 ? 225.903 243.610 201.278 1.00 68.30  ? 540 PRO B N   1 
ATOM   10394 C  CA  . PRO B 1 540 ? 225.346 244.582 200.321 1.00 68.30  ? 540 PRO B CA  1 
ATOM   10395 C  C   . PRO B 1 540 ? 225.835 244.366 198.899 1.00 68.30  ? 540 PRO B C   1 
ATOM   10396 O  O   . PRO B 1 540 ? 225.078 244.580 197.942 1.00 68.30  ? 540 PRO B O   1 
ATOM   10397 C  CB  . PRO B 1 540 ? 225.796 245.938 200.881 1.00 68.30  ? 540 PRO B CB  1 
ATOM   10398 C  CG  . PRO B 1 540 ? 226.306 245.691 202.248 1.00 68.30  ? 540 PRO B CG  1 
ATOM   10399 C  CD  . PRO B 1 540 ? 226.447 244.232 202.494 1.00 68.30  ? 540 PRO B CD  1 
ATOM   10400 N  N   . ALA B 1 541 ? 227.089 243.940 198.729 1.00 69.20  ? 541 ALA B N   1 
ATOM   10401 C  CA  . ALA B 1 541 ? 227.589 243.653 197.388 1.00 69.20  ? 541 ALA B CA  1 
ATOM   10402 C  C   . ALA B 1 541 ? 226.729 242.600 196.705 1.00 69.20  ? 541 ALA B C   1 
ATOM   10403 O  O   . ALA B 1 541 ? 226.517 242.645 195.488 1.00 69.20  ? 541 ALA B O   1 
ATOM   10404 C  CB  . ALA B 1 541 ? 229.048 243.203 197.458 1.00 69.20  ? 541 ALA B CB  1 
ATOM   10405 N  N   . MET B 1 542 ? 226.226 241.641 197.480 1.00 64.56  ? 542 MET B N   1 
ATOM   10406 C  CA  . MET B 1 542 ? 225.267 240.668 196.986 1.00 64.56  ? 542 MET B CA  1 
ATOM   10407 C  C   . MET B 1 542 ? 223.841 241.194 197.013 1.00 64.56  ? 542 MET B C   1 
ATOM   10408 O  O   . MET B 1 542 ? 222.944 240.528 196.488 1.00 64.56  ? 542 MET B O   1 
ATOM   10409 C  CB  . MET B 1 542 ? 225.374 239.389 197.818 1.00 64.56  ? 542 MET B CB  1 
ATOM   10410 C  CG  . MET B 1 542 ? 224.909 238.119 197.133 1.00 64.56  ? 542 MET B CG  1 
ATOM   10411 S  SD  . MET B 1 542 ? 224.994 236.704 198.247 1.00 64.56  ? 542 MET B SD  1 
ATOM   10412 C  CE  . MET B 1 542 ? 224.742 235.363 197.092 1.00 64.56  ? 542 MET B CE  1 
ATOM   10413 N  N   . ASN B 1 543 ? 223.608 242.359 197.608 1.00 66.10  ? 543 ASN B N   1 
ATOM   10414 C  CA  . ASN B 1 543 ? 222.247 242.840 197.799 1.00 66.10  ? 543 ASN B CA  1 
ATOM   10415 C  C   . ASN B 1 543 ? 221.795 243.854 196.756 1.00 66.10  ? 543 ASN B C   1 
ATOM   10416 O  O   . ASN B 1 543 ? 220.641 243.792 196.321 1.00 66.10  ? 543 ASN B O   1 
ATOM   10417 C  CB  . ASN B 1 543 ? 222.093 243.453 199.197 1.00 66.10  ? 543 ASN B CB  1 
ATOM   10418 C  CG  . ASN B 1 543 ? 220.639 243.580 199.625 1.00 66.10  ? 543 ASN B CG  1 
ATOM   10419 O  OD1 . ASN B 1 543 ? 219.728 243.185 198.898 1.00 66.10  ? 543 ASN B OD1 1 
ATOM   10420 N  ND2 . ASN B 1 543 ? 220.417 244.144 200.807 1.00 66.10  ? 543 ASN B ND2 1 
ATOM   10421 N  N   . GLU B 1 544 ? 222.649 244.788 196.337 1.00 68.11  ? 544 GLU B N   1 
ATOM   10422 C  CA  . GLU B 1 544 ? 222.170 245.757 195.350 1.00 68.11  ? 544 GLU B CA  1 
ATOM   10423 C  C   . GLU B 1 544 ? 221.956 245.139 193.970 1.00 68.11  ? 544 GLU B C   1 
ATOM   10424 O  O   . GLU B 1 544 ? 221.345 245.785 193.110 1.00 68.11  ? 544 GLU B O   1 
ATOM   10425 C  CB  . GLU B 1 544 ? 223.084 246.980 195.176 1.00 68.11  ? 544 GLU B CB  1 
ATOM   10426 C  CG  . GLU B 1 544 ? 223.178 247.949 196.350 1.00 68.11  ? 544 GLU B CG  1 
ATOM   10427 C  CD  . GLU B 1 544 ? 224.348 247.677 197.257 1.00 68.11  ? 544 GLU B CD  1 
ATOM   10428 O  OE1 . GLU B 1 544 ? 225.189 246.835 196.898 1.00 68.11  ? 544 GLU B OE1 1 
ATOM   10429 O  OE2 . GLU B 1 544 ? 224.431 248.313 198.327 1.00 68.11  ? 544 GLU B OE2 1 
ATOM   10430 N  N   . MET B 1 545 ? 222.454 243.923 193.724 1.00 65.39  ? 545 MET B N   1 
ATOM   10431 C  CA  . MET B 1 545 ? 222.213 243.286 192.432 1.00 65.39  ? 545 MET B CA  1 
ATOM   10432 C  C   . MET B 1 545 ? 220.727 243.057 192.209 1.00 65.39  ? 545 MET B C   1 
ATOM   10433 O  O   . MET B 1 545 ? 220.226 243.223 191.092 1.00 65.39  ? 545 MET B O   1 
ATOM   10434 C  CB  . MET B 1 545 ? 222.973 241.966 192.334 1.00 65.39  ? 545 MET B CB  1 
ATOM   10435 C  CG  . MET B 1 545 ? 224.469 242.119 192.161 1.00 65.39  ? 545 MET B CG  1 
ATOM   10436 S  SD  . MET B 1 545 ? 225.280 240.558 191.770 1.00 65.39  ? 545 MET B SD  1 
ATOM   10437 C  CE  . MET B 1 545 ? 225.144 239.707 193.338 1.00 65.39  ? 545 MET B CE  1 
ATOM   10438 N  N   . VAL B 1 546 ? 220.009 242.665 193.259 1.00 60.41  ? 546 VAL B N   1 
ATOM   10439 C  CA  . VAL B 1 546 ? 218.568 242.479 193.147 1.00 60.41  ? 546 VAL B CA  1 
ATOM   10440 C  C   . VAL B 1 546 ? 217.891 243.793 192.790 1.00 60.41  ? 546 VAL B C   1 
ATOM   10441 O  O   . VAL B 1 546 ? 216.982 243.832 191.952 1.00 60.41  ? 546 VAL B O   1 
ATOM   10442 C  CB  . VAL B 1 546 ? 218.009 241.891 194.453 1.00 60.41  ? 546 VAL B CB  1 
ATOM   10443 C  CG1 . VAL B 1 546 ? 216.500 241.962 194.457 1.00 60.41  ? 546 VAL B CG1 1 
ATOM   10444 C  CG2 . VAL B 1 546 ? 218.478 240.460 194.623 1.00 60.41  ? 546 VAL B CG2 1 
ATOM   10445 N  N   . LYS B 1 547 ? 218.318 244.889 193.417 1.00 63.65  ? 547 LYS B N   1 
ATOM   10446 C  CA  . LYS B 1 547 ? 217.740 246.190 193.096 1.00 63.65  ? 547 LYS B CA  1 
ATOM   10447 C  C   . LYS B 1 547 ? 218.016 246.568 191.648 1.00 63.65  ? 547 LYS B C   1 
ATOM   10448 O  O   . LYS B 1 547 ? 217.128 247.068 190.945 1.00 63.65  ? 547 LYS B O   1 
ATOM   10449 C  CB  . LYS B 1 547 ? 218.285 247.256 194.044 1.00 63.65  ? 547 LYS B CB  1 
ATOM   10450 C  CG  . LYS B 1 547 ? 217.759 247.146 195.467 1.00 63.65  ? 547 LYS B CG  1 
ATOM   10451 C  CD  . LYS B 1 547 ? 218.148 248.357 196.298 1.00 63.65  ? 547 LYS B CD  1 
ATOM   10452 C  CE  . LYS B 1 547 ? 219.567 248.229 196.822 1.00 63.65  ? 547 LYS B CE  1 
ATOM   10453 N  NZ  . LYS B 1 547 ? 219.619 247.475 198.105 1.00 63.65  ? 547 LYS B NZ  1 
ATOM   10454 N  N   . GLU B 1 548 ? 219.242 246.328 191.182 1.00 62.41  ? 548 GLU B N   1 
ATOM   10455 C  CA  . GLU B 1 548 ? 219.574 246.627 189.793 1.00 62.41  ? 548 GLU B CA  1 
ATOM   10456 C  C   . GLU B 1 548 ? 218.720 245.807 188.833 1.00 62.41  ? 548 GLU B C   1 
ATOM   10457 O  O   . GLU B 1 548 ? 218.226 246.328 187.826 1.00 62.41  ? 548 GLU B O   1 
ATOM   10458 C  CB  . GLU B 1 548 ? 221.059 246.371 189.541 1.00 62.41  ? 548 GLU B CB  1 
ATOM   10459 C  CG  . GLU B 1 548 ? 221.987 247.363 190.222 1.00 62.41  ? 548 GLU B CG  1 
ATOM   10460 C  CD  . GLU B 1 548 ? 223.408 247.291 189.697 1.00 62.41  ? 548 GLU B CD  1 
ATOM   10461 O  OE1 . GLU B 1 548 ? 223.883 246.172 189.408 1.00 62.41  ? 548 GLU B OE1 1 
ATOM   10462 O  OE2 . GLU B 1 548 ? 224.051 248.354 189.572 1.00 62.41  ? 548 GLU B OE2 1 
ATOM   10463 N  N   . ARG B 1 549 ? 218.540 244.520 189.126 1.00 56.13  ? 549 ARG B N   1 
ATOM   10464 C  CA  . ARG B 1 549 ? 217.737 243.674 188.253 1.00 56.13  ? 549 ARG B CA  1 
ATOM   10465 C  C   . ARG B 1 549 ? 216.277 244.088 188.265 1.00 56.13  ? 549 ARG B C   1 
ATOM   10466 O  O   . ARG B 1 549 ? 215.603 244.005 187.237 1.00 56.13  ? 549 ARG B O   1 
ATOM   10467 C  CB  . ARG B 1 549 ? 217.883 242.213 188.659 1.00 56.13  ? 549 ARG B CB  1 
ATOM   10468 C  CG  . ARG B 1 549 ? 219.235 241.632 188.315 1.00 56.13  ? 549 ARG B CG  1 
ATOM   10469 C  CD  . ARG B 1 549 ? 219.292 240.162 188.649 1.00 56.13  ? 549 ARG B CD  1 
ATOM   10470 N  NE  . ARG B 1 549 ? 218.426 239.380 187.779 1.00 56.13  ? 549 ARG B NE  1 
ATOM   10471 C  CZ  . ARG B 1 549 ? 218.044 238.138 188.033 1.00 56.13  ? 549 ARG B CZ  1 
ATOM   10472 N  NH1 . ARG B 1 549 ? 218.427 237.509 189.131 1.00 56.13  ? 549 ARG B NH1 1 
ATOM   10473 N  NH2 . ARG B 1 549 ? 217.252 237.512 187.167 1.00 56.13  ? 549 ARG B NH2 1 
ATOM   10474 N  N   . LEU B 1 550 ? 215.772 244.533 189.412 1.00 57.99  ? 550 LEU B N   1 
ATOM   10475 C  CA  . LEU B 1 550 ? 214.418 245.067 189.451 1.00 57.99  ? 550 LEU B CA  1 
ATOM   10476 C  C   . LEU B 1 550 ? 214.305 246.311 188.583 1.00 57.99  ? 550 LEU B C   1 
ATOM   10477 O  O   . LEU B 1 550 ? 213.311 246.496 187.870 1.00 57.99  ? 550 LEU B O   1 
ATOM   10478 C  CB  . LEU B 1 550 ? 214.016 245.376 190.892 1.00 57.99  ? 550 LEU B CB  1 
ATOM   10479 C  CG  . LEU B 1 550 ? 213.696 244.173 191.780 1.00 57.99  ? 550 LEU B CG  1 
ATOM   10480 C  CD1 . LEU B 1 550 ? 213.753 244.565 193.247 1.00 57.99  ? 550 LEU B CD1 1 
ATOM   10481 C  CD2 . LEU B 1 550 ? 212.336 243.597 191.428 1.00 57.99  ? 550 LEU B CD2 1 
ATOM   10482 N  N   . VAL B 1 551 ? 215.320 247.175 188.627 1.00 54.48  ? 551 VAL B N   1 
ATOM   10483 C  CA  . VAL B 1 551 ? 215.301 248.368 187.787 1.00 54.48  ? 551 VAL B CA  1 
ATOM   10484 C  C   . VAL B 1 551 ? 215.290 247.977 186.317 1.00 54.48  ? 551 VAL B C   1 
ATOM   10485 O  O   . VAL B 1 551 ? 214.543 248.546 185.511 1.00 54.48  ? 551 VAL B O   1 
ATOM   10486 C  CB  . VAL B 1 551 ? 216.495 249.278 188.122 1.00 54.48  ? 551 VAL B CB  1 
ATOM   10487 C  CG1 . VAL B 1 551 ? 216.598 250.407 187.112 1.00 54.48  ? 551 VAL B CG1 1 
ATOM   10488 C  CG2 . VAL B 1 551 ? 216.352 249.838 189.525 1.00 54.48  ? 551 VAL B CG2 1 
ATOM   10489 N  N   . LEU B 1 552 ? 216.113 246.995 185.947 1.00 53.35  ? 552 LEU B N   1 
ATOM   10490 C  CA  . LEU B 1 552 ? 216.163 246.545 184.559 1.00 53.35  ? 552 LEU B CA  1 
ATOM   10491 C  C   . LEU B 1 552 ? 214.831 245.945 184.125 1.00 53.35  ? 552 LEU B C   1 
ATOM   10492 O  O   . LEU B 1 552 ? 214.375 246.175 182.999 1.00 53.35  ? 552 LEU B O   1 
ATOM   10493 C  CB  . LEU B 1 552 ? 217.293 245.535 184.376 1.00 53.35  ? 552 LEU B CB  1 
ATOM   10494 C  CG  . LEU B 1 552 ? 217.599 245.109 182.946 1.00 53.35  ? 552 LEU B CG  1 
ATOM   10495 C  CD1 . LEU B 1 552 ? 217.602 246.310 182.026 1.00 53.35  ? 552 LEU B CD1 1 
ATOM   10496 C  CD2 . LEU B 1 552 ? 218.934 244.408 182.893 1.00 53.35  ? 552 LEU B CD2 1 
ATOM   10497 N  N   . GLY B 1 553 ? 214.194 245.170 185.004 1.00 52.53  ? 553 GLY B N   1 
ATOM   10498 C  CA  . GLY B 1 553 ? 212.895 244.611 184.673 1.00 52.53  ? 553 GLY B CA  1 
ATOM   10499 C  C   . GLY B 1 553 ? 211.839 245.681 184.485 1.00 52.53  ? 553 GLY B C   1 
ATOM   10500 O  O   . GLY B 1 553 ? 211.013 245.600 183.572 1.00 52.53  ? 553 GLY B O   1 
ATOM   10501 N  N   . ALA B 1 554 ? 211.852 246.696 185.344 1.00 50.81  ? 554 ALA B N   1 
ATOM   10502 C  CA  . ALA B 1 554 ? 210.919 247.802 185.177 1.00 50.81  ? 554 ALA B CA  1 
ATOM   10503 C  C   . ALA B 1 554 ? 211.164 248.516 183.859 1.00 50.81  ? 554 ALA B C   1 
ATOM   10504 O  O   . ALA B 1 554 ? 210.214 248.888 183.153 1.00 50.81  ? 554 ALA B O   1 
ATOM   10505 C  CB  . ALA B 1 554 ? 211.040 248.776 186.347 1.00 50.81  ? 554 ALA B CB  1 
ATOM   10506 N  N   . ALA B 1 555 ? 212.433 248.711 183.508 1.00 49.36  ? 555 ALA B N   1 
ATOM   10507 C  CA  . ALA B 1 555 ? 212.752 249.343 182.236 1.00 49.36  ? 555 ALA B CA  1 
ATOM   10508 C  C   . ALA B 1 555 ? 212.218 248.519 181.074 1.00 49.36  ? 555 ALA B C   1 
ATOM   10509 O  O   . ALA B 1 555 ? 211.644 249.063 180.125 1.00 49.36  ? 555 ALA B O   1 
ATOM   10510 C  CB  . ALA B 1 555 ? 214.261 249.538 182.114 1.00 49.36  ? 555 ALA B CB  1 
ATOM   10511 N  N   . LEU B 1 556 ? 212.401 247.199 181.134 1.00 48.42  ? 556 LEU B N   1 
ATOM   10512 C  CA  . LEU B 1 556 ? 211.928 246.340 180.055 1.00 48.42  ? 556 LEU B CA  1 
ATOM   10513 C  C   . LEU B 1 556 ? 210.418 246.402 179.931 1.00 48.42  ? 556 LEU B C   1 
ATOM   10514 O  O   . LEU B 1 556 ? 209.883 246.462 178.820 1.00 48.42  ? 556 LEU B O   1 
ATOM   10515 C  CB  . LEU B 1 556 ? 212.380 244.900 180.283 1.00 48.42  ? 556 LEU B CB  1 
ATOM   10516 C  CG  . LEU B 1 556 ? 211.676 243.839 179.441 1.00 48.42  ? 556 LEU B CG  1 
ATOM   10517 C  CD1 . LEU B 1 556 ? 212.085 243.941 178.000 1.00 48.42  ? 556 LEU B CD1 1 
ATOM   10518 C  CD2 . LEU B 1 556 ? 211.964 242.457 179.970 1.00 48.42  ? 556 LEU B CD2 1 
ATOM   10519 N  N   . LYS B 1 557 ? 209.711 246.376 181.060 1.00 54.81  ? 557 LYS B N   1 
ATOM   10520 C  CA  . LYS B 1 557 ? 208.254 246.445 181.012 1.00 54.81  ? 557 LYS B CA  1 
ATOM   10521 C  C   . LYS B 1 557 ? 207.795 247.753 180.385 1.00 54.81  ? 557 LYS B C   1 
ATOM   10522 O  O   . LYS B 1 557 ? 206.943 247.764 179.485 1.00 54.81  ? 557 LYS B O   1 
ATOM   10523 C  CB  . LYS B 1 557 ? 207.673 246.284 182.417 1.00 54.81  ? 557 LYS B CB  1 
ATOM   10524 C  CG  . LYS B 1 557 ? 207.197 244.877 182.734 1.00 54.81  ? 557 LYS B CG  1 
ATOM   10525 C  CD  . LYS B 1 557 ? 206.568 244.803 184.115 1.00 54.81  ? 557 LYS B CD  1 
ATOM   10526 C  CE  . LYS B 1 557 ? 205.896 243.459 184.343 1.00 54.81  ? 557 LYS B CE  1 
ATOM   10527 N  NZ  . LYS B 1 557 ? 204.580 243.373 183.652 1.00 54.81  ? 557 LYS B NZ  1 
ATOM   10528 N  N   . GLU B 1 558 ? 208.373 248.870 180.830 1.00 57.91  ? 558 GLU B N   1 
ATOM   10529 C  CA  . GLU B 1 558 ? 207.989 250.161 180.270 1.00 57.91  ? 558 GLU B CA  1 
ATOM   10530 C  C   . GLU B 1 558 ? 208.283 250.219 178.779 1.00 57.91  ? 558 GLU B C   1 
ATOM   10531 O  O   . GLU B 1 558 ? 207.466 250.711 177.996 1.00 57.91  ? 558 GLU B O   1 
ATOM   10532 C  CB  . GLU B 1 558 ? 208.712 251.290 181.005 1.00 57.91  ? 558 GLU B CB  1 
ATOM   10533 C  CG  . GLU B 1 558 ? 208.254 251.494 182.441 1.00 57.91  ? 558 GLU B CG  1 
ATOM   10534 C  CD  . GLU B 1 558 ? 206.786 251.858 182.539 1.00 57.91  ? 558 GLU B CD  1 
ATOM   10535 O  OE1 . GLU B 1 558 ? 206.306 252.637 181.689 1.00 57.91  ? 558 GLU B OE1 1 
ATOM   10536 O  OE2 . GLU B 1 558 ? 206.111 251.366 183.468 1.00 57.91  ? 558 GLU B OE2 1 
ATOM   10537 N  N   . ALA B 1 559 ? 209.437 249.700 178.363 1.00 53.78  ? 559 ALA B N   1 
ATOM   10538 C  CA  . ALA B 1 559 ? 209.823 249.791 176.961 1.00 53.78  ? 559 ALA B CA  1 
ATOM   10539 C  C   . ALA B 1 559 ? 208.943 248.915 176.083 1.00 53.78  ? 559 ALA B C   1 
ATOM   10540 O  O   . ALA B 1 559 ? 208.548 249.322 174.986 1.00 53.78  ? 559 ALA B O   1 
ATOM   10541 C  CB  . ALA B 1 559 ? 211.291 249.410 176.799 1.00 53.78  ? 559 ALA B CB  1 
ATOM   10542 N  N   . ILE B 1 560 ? 208.637 247.698 176.535 1.00 52.47  ? 560 ILE B N   1 
ATOM   10543 C  CA  . ILE B 1 560 ? 207.799 246.824 175.725 1.00 52.47  ? 560 ILE B CA  1 
ATOM   10544 C  C   . ILE B 1 560 ? 206.387 247.378 175.647 1.00 52.47  ? 560 ILE B C   1 
ATOM   10545 O  O   . ILE B 1 560 ? 205.696 247.205 174.637 1.00 52.47  ? 560 ILE B O   1 
ATOM   10546 C  CB  . ILE B 1 560 ? 207.827 245.382 176.255 1.00 52.47  ? 560 ILE B CB  1 
ATOM   10547 C  CG1 . ILE B 1 560 ? 207.161 244.448 175.252 1.00 52.47  ? 560 ILE B CG1 1 
ATOM   10548 C  CG2 . ILE B 1 560 ? 207.142 245.276 177.597 1.00 52.47  ? 560 ILE B CG2 1 
ATOM   10549 C  CD1 . ILE B 1 560 ? 207.756 244.528 173.869 1.00 52.47  ? 560 ILE B CD1 1 
ATOM   10550 N  N   . SER B 1 561 ? 205.937 248.067 176.700 1.00 58.10  ? 561 SER B N   1 
ATOM   10551 C  CA  . SER B 1 561 ? 204.660 248.766 176.609 1.00 58.10  ? 561 SER B CA  1 
ATOM   10552 C  C   . SER B 1 561 ? 204.734 249.915 175.611 1.00 58.10  ? 561 SER B C   1 
ATOM   10553 O  O   . SER B 1 561 ? 203.805 250.125 174.823 1.00 58.10  ? 561 SER B O   1 
ATOM   10554 C  CB  . SER B 1 561 ? 204.239 249.277 177.987 1.00 58.10  ? 561 SER B CB  1 
ATOM   10555 O  OG  . SER B 1 561 ? 205.202 250.171 178.514 1.00 58.10  ? 561 SER B OG  1 
ATOM   10556 N  N   . ASN B 1 562 ? 205.838 250.660 175.618 1.00 55.44  ? 562 ASN B N   1 
ATOM   10557 C  CA  . ASN B 1 562 ? 205.963 251.864 174.808 1.00 55.44  ? 562 ASN B CA  1 
ATOM   10558 C  C   . ASN B 1 562 ? 206.418 251.590 173.383 1.00 55.44  ? 562 ASN B C   1 
ATOM   10559 O  O   . ASN B 1 562 ? 206.541 252.540 172.604 1.00 55.44  ? 562 ASN B O   1 
ATOM   10560 C  CB  . ASN B 1 562 ? 206.931 252.841 175.475 1.00 55.44  ? 562 ASN B CB  1 
ATOM   10561 C  CG  . ASN B 1 562 ? 206.358 253.459 176.727 1.00 55.44  ? 562 ASN B CG  1 
ATOM   10562 O  OD1 . ASN B 1 562 ? 205.946 254.618 176.730 1.00 55.44  ? 562 ASN B OD1 1 
ATOM   10563 N  ND2 . ASN B 1 562 ? 206.322 252.686 177.803 1.00 55.44  ? 562 ASN B ND2 1 
ATOM   10564 N  N   . ASN B 1 563 ? 206.673 250.331 173.027 1.00 56.34  ? 563 ASN B N   1 
ATOM   10565 C  CA  . ASN B 1 563 ? 207.021 249.941 171.661 1.00 56.34  ? 563 ASN B CA  1 
ATOM   10566 C  C   . ASN B 1 563 ? 208.293 250.653 171.187 1.00 56.34  ? 563 ASN B C   1 
ATOM   10567 O  O   . ASN B 1 563 ? 208.281 251.497 170.291 1.00 56.34  ? 563 ASN B O   1 
ATOM   10568 C  CB  . ASN B 1 563 ? 205.849 250.208 170.711 1.00 56.34  ? 563 ASN B CB  1 
ATOM   10569 C  CG  . ASN B 1 563 ? 206.144 249.789 169.288 1.00 56.34  ? 563 ASN B CG  1 
ATOM   10570 O  OD1 . ASN B 1 563 ? 206.392 250.626 168.423 1.00 56.34  ? 563 ASN B OD1 1 
ATOM   10571 N  ND2 . ASN B 1 563 ? 206.119 248.486 169.037 1.00 56.34  ? 563 ASN B ND2 1 
ATOM   10572 N  N   . GLN B 1 564 ? 209.404 250.303 171.838 1.00 53.50  ? 564 GLN B N   1 
ATOM   10573 C  CA  . GLN B 1 564 ? 210.700 250.818 171.417 1.00 53.50  ? 564 GLN B CA  1 
ATOM   10574 C  C   . GLN B 1 564 ? 211.767 249.727 171.397 1.00 53.50  ? 564 GLN B C   1 
ATOM   10575 O  O   . GLN B 1 564 ? 212.947 250.006 171.623 1.00 53.50  ? 564 GLN B O   1 
ATOM   10576 C  CB  . GLN B 1 564 ? 211.149 251.979 172.301 1.00 53.50  ? 564 GLN B CB  1 
ATOM   10577 C  CG  . GLN B 1 564 ? 211.387 251.617 173.747 1.00 53.50  ? 564 GLN B CG  1 
ATOM   10578 C  CD  . GLN B 1 564 ? 211.768 252.820 174.570 1.00 53.50  ? 564 GLN B CD  1 
ATOM   10579 O  OE1 . GLN B 1 564 ? 211.867 253.929 174.050 1.00 53.50  ? 564 GLN B OE1 1 
ATOM   10580 N  NE2 . GLN B 1 564 ? 211.987 252.611 175.862 1.00 53.50  ? 564 GLN B NE2 1 
ATOM   10581 N  N   . LEU B 1 565 ? 211.376 248.485 171.124 1.00 44.63  ? 565 LEU B N   1 
ATOM   10582 C  CA  . LEU B 1 565 ? 212.337 247.420 170.906 1.00 44.63  ? 565 LEU B CA  1 
ATOM   10583 C  C   . LEU B 1 565 ? 212.728 247.382 169.429 1.00 44.63  ? 565 LEU B C   1 
ATOM   10584 O  O   . LEU B 1 565 ? 212.205 248.135 168.605 1.00 44.63  ? 565 LEU B O   1 
ATOM   10585 C  CB  . LEU B 1 565 ? 211.768 246.089 171.381 1.00 44.63  ? 565 LEU B CB  1 
ATOM   10586 C  CG  . LEU B 1 565 ? 211.929 245.781 172.869 1.00 44.63  ? 565 LEU B CG  1 
ATOM   10587 C  CD1 . LEU B 1 565 ? 210.935 246.574 173.695 1.00 44.63  ? 565 LEU B CD1 1 
ATOM   10588 C  CD2 . LEU B 1 565 ? 211.769 244.306 173.141 1.00 44.63  ? 565 LEU B CD2 1 
ATOM   10589 N  N   . LYS B 1 566 ? 213.654 246.495 169.077 1.00 41.84  ? 566 LYS B N   1 
ATOM   10590 C  CA  . LYS B 1 566 ? 214.239 246.509 167.745 1.00 41.84  ? 566 LYS B CA  1 
ATOM   10591 C  C   . LYS B 1 566 ? 214.351 245.092 167.205 1.00 41.84  ? 566 LYS B C   1 
ATOM   10592 O  O   . LYS B 1 566 ? 214.432 244.123 167.962 1.00 41.84  ? 566 LYS B O   1 
ATOM   10593 C  CB  . LYS B 1 566 ? 215.612 247.179 167.753 1.00 41.84  ? 566 LYS B CB  1 
ATOM   10594 C  CG  . LYS B 1 566 ? 216.024 247.767 166.415 1.00 41.84  ? 566 LYS B CG  1 
ATOM   10595 C  CD  . LYS B 1 566 ? 217.245 248.666 166.554 1.00 41.84  ? 566 LYS B CD  1 
ATOM   10596 C  CE  . LYS B 1 566 ? 217.069 249.685 167.670 1.00 41.84  ? 566 LYS B CE  1 
ATOM   10597 N  NZ  . LYS B 1 566 ? 215.828 250.492 167.500 1.00 41.84  ? 566 LYS B NZ  1 
ATOM   10598 N  N   . LEU B 1 567 ? 214.356 244.983 165.874 1.00 40.11  ? 567 LEU B N   1 
ATOM   10599 C  CA  . LEU B 1 567 ? 214.442 243.707 165.176 1.00 40.11  ? 567 LEU B CA  1 
ATOM   10600 C  C   . LEU B 1 567 ? 215.512 243.762 164.098 1.00 40.11  ? 567 LEU B C   1 
ATOM   10601 O  O   . LEU B 1 567 ? 215.618 244.749 163.367 1.00 40.11  ? 567 LEU B O   1 
ATOM   10602 C  CB  . LEU B 1 567 ? 213.118 243.326 164.535 1.00 40.11  ? 567 LEU B CB  1 
ATOM   10603 C  CG  . LEU B 1 567 ? 212.242 242.401 165.358 1.00 40.11  ? 567 LEU B CG  1 
ATOM   10604 C  CD1 . LEU B 1 567 ? 211.126 241.844 164.503 1.00 40.11  ? 567 LEU B CD1 1 
ATOM   10605 C  CD2 . LEU B 1 567 ? 213.076 241.293 165.931 1.00 40.11  ? 567 LEU B CD2 1 
ATOM   10606 N  N   . VAL B 1 568 ? 216.293 242.690 163.995 1.00 42.59  ? 568 VAL B N   1 
ATOM   10607 C  CA  . VAL B 1 568 ? 217.348 242.577 163.000 1.00 42.59  ? 568 VAL B CA  1 
ATOM   10608 C  C   . VAL B 1 568 ? 217.118 241.303 162.204 1.00 42.59  ? 568 VAL B C   1 
ATOM   10609 O  O   . VAL B 1 568 ? 216.455 240.371 162.668 1.00 42.59  ? 568 VAL B O   1 
ATOM   10610 C  CB  . VAL B 1 568 ? 218.747 242.585 163.641 1.00 42.59  ? 568 VAL B CB  1 
ATOM   10611 C  CG1 . VAL B 1 568 ? 219.002 243.916 164.316 1.00 42.59  ? 568 VAL B CG1 1 
ATOM   10612 C  CG2 . VAL B 1 568 ? 218.876 241.463 164.630 1.00 42.59  ? 568 VAL B CG2 1 
ATOM   10613 N  N   . TYR B 1 569 ? 217.671 241.264 160.994 1.00 45.70  ? 569 TYR B N   1 
ATOM   10614 C  CA  . TYR B 1 569 ? 217.310 240.253 160.008 1.00 45.70  ? 569 TYR B CA  1 
ATOM   10615 C  C   . TYR B 1 569 ? 218.547 239.508 159.521 1.00 45.70  ? 569 TYR B C   1 
ATOM   10616 O  O   . TYR B 1 569 ? 219.290 240.011 158.673 1.00 45.70  ? 569 TYR B O   1 
ATOM   10617 C  CB  . TYR B 1 569 ? 216.562 240.907 158.855 1.00 45.70  ? 569 TYR B CB  1 
ATOM   10618 C  CG  . TYR B 1 569 ? 215.215 241.397 159.283 1.00 45.70  ? 569 TYR B CG  1 
ATOM   10619 C  CD1 . TYR B 1 569 ? 214.168 240.519 159.450 1.00 45.70  ? 569 TYR B CD1 1 
ATOM   10620 C  CD2 . TYR B 1 569 ? 214.996 242.731 159.545 1.00 45.70  ? 569 TYR B CD2 1 
ATOM   10621 C  CE1 . TYR B 1 569 ? 212.938 240.956 159.846 1.00 45.70  ? 569 TYR B CE1 1 
ATOM   10622 C  CE2 . TYR B 1 569 ? 213.770 243.180 159.941 1.00 45.70  ? 569 TYR B CE2 1 
ATOM   10623 C  CZ  . TYR B 1 569 ? 212.742 242.288 160.093 1.00 45.70  ? 569 TYR B CZ  1 
ATOM   10624 O  OH  . TYR B 1 569 ? 211.504 242.727 160.497 1.00 45.70  ? 569 TYR B OH  1 
ATOM   10625 N  N   . GLN B 1 570 ? 218.755 238.310 160.051 1.00 44.24  ? 570 GLN B N   1 
ATOM   10626 C  CA  . GLN B 1 570 ? 219.801 237.443 159.543 1.00 44.24  ? 570 GLN B CA  1 
ATOM   10627 C  C   . GLN B 1 570 ? 219.441 236.983 158.137 1.00 44.24  ? 570 GLN B C   1 
ATOM   10628 O  O   . GLN B 1 570 ? 218.290 236.635 157.881 1.00 44.24  ? 570 GLN B O   1 
ATOM   10629 C  CB  . GLN B 1 570 ? 219.974 236.234 160.453 1.00 44.24  ? 570 GLN B CB  1 
ATOM   10630 C  CG  . GLN B 1 570 ? 221.206 235.394 160.168 1.00 44.24  ? 570 GLN B CG  1 
ATOM   10631 C  CD  . GLN B 1 570 ? 222.420 235.881 160.922 1.00 44.24  ? 570 GLN B CD  1 
ATOM   10632 O  OE1 . GLN B 1 570 ? 222.566 237.074 161.164 1.00 44.24  ? 570 GLN B OE1 1 
ATOM   10633 N  NE2 . GLN B 1 570 ? 223.297 234.959 161.301 1.00 44.24  ? 570 GLN B NE2 1 
ATOM   10634 N  N   . PRO B 1 571 ? 220.385 236.989 157.204 1.00 45.27  ? 571 PRO B N   1 
ATOM   10635 C  CA  . PRO B 1 571 ? 220.095 236.478 155.859 1.00 45.27  ? 571 PRO B CA  1 
ATOM   10636 C  C   . PRO B 1 571 ? 220.506 235.023 155.662 1.00 45.27  ? 571 PRO B C   1 
ATOM   10637 O  O   . PRO B 1 571 ? 221.564 234.605 156.136 1.00 45.27  ? 571 PRO B O   1 
ATOM   10638 C  CB  . PRO B 1 571 ? 220.907 237.414 154.965 1.00 45.27  ? 571 PRO B CB  1 
ATOM   10639 C  CG  . PRO B 1 571 ? 222.084 237.778 155.807 1.00 45.27  ? 571 PRO B CG  1 
ATOM   10640 C  CD  . PRO B 1 571 ? 221.697 237.649 157.263 1.00 45.27  ? 571 PRO B CD  1 
ATOM   10641 N  N   . GLN B 1 572 ? 219.683 234.246 154.953 1.00 44.95  ? 572 GLN B N   1 
ATOM   10642 C  CA  . GLN B 1 572 ? 219.959 232.846 154.652 1.00 44.95  ? 572 GLN B CA  1 
ATOM   10643 C  C   . GLN B 1 572 ? 220.005 232.640 153.145 1.00 44.95  ? 572 GLN B C   1 
ATOM   10644 O  O   . GLN B 1 572 ? 219.087 233.044 152.424 1.00 44.95  ? 572 GLN B O   1 
ATOM   10645 C  CB  . GLN B 1 572 ? 218.908 231.928 155.270 1.00 44.95  ? 572 GLN B CB  1 
ATOM   10646 C  CG  . GLN B 1 572 ? 219.077 231.744 156.754 1.00 44.95  ? 572 GLN B CG  1 
ATOM   10647 C  CD  . GLN B 1 572 ? 217.771 231.746 157.505 1.00 44.95  ? 572 GLN B CD  1 
ATOM   10648 O  OE1 . GLN B 1 572 ? 216.696 231.746 156.912 1.00 44.95  ? 572 GLN B OE1 1 
ATOM   10649 N  NE2 . GLN B 1 572 ? 217.856 231.746 158.825 1.00 44.95  ? 572 GLN B NE2 1 
ATOM   10650 N  N   . ILE B 1 573 ? 221.071 231.996 152.675 1.00 46.34  ? 573 ILE B N   1 
ATOM   10651 C  CA  . ILE B 1 573 ? 221.394 231.939 151.254 1.00 46.34  ? 573 ILE B CA  1 
ATOM   10652 C  C   . ILE B 1 573 ? 221.778 230.514 150.878 1.00 46.34  ? 573 ILE B C   1 
ATOM   10653 O  O   . ILE B 1 573 ? 222.497 229.841 151.623 1.00 46.34  ? 573 ILE B O   1 
ATOM   10654 C  CB  . ILE B 1 573 ? 222.530 232.926 150.911 1.00 46.34  ? 573 ILE B CB  1 
ATOM   10655 C  CG1 . ILE B 1 573 ? 222.046 234.367 151.045 1.00 46.34  ? 573 ILE B CG1 1 
ATOM   10656 C  CG2 . ILE B 1 573 ? 223.044 232.700 149.511 1.00 46.34  ? 573 ILE B CG2 1 
ATOM   10657 C  CD1 . ILE B 1 573 ? 223.150 235.356 151.316 1.00 46.34  ? 573 ILE B CD1 1 
ATOM   10658 N  N   . PHE B 1 574 ? 221.287 230.051 149.725 1.00 43.35  ? 574 PHE B N   1 
ATOM   10659 C  CA  . PHE B 1 574 ? 221.751 228.787 149.171 1.00 43.35  ? 574 PHE B CA  1 
ATOM   10660 C  C   . PHE B 1 574 ? 223.259 228.835 149.005 1.00 43.35  ? 574 PHE B C   1 
ATOM   10661 O  O   . PHE B 1 574 ? 223.812 229.835 148.541 1.00 43.35  ? 574 PHE B O   1 
ATOM   10662 C  CB  . PHE B 1 574 ? 221.116 228.516 147.810 1.00 43.35  ? 574 PHE B CB  1 
ATOM   10663 C  CG  . PHE B 1 574 ? 219.642 228.329 147.841 1.00 43.35  ? 574 PHE B CG  1 
ATOM   10664 C  CD1 . PHE B 1 574 ? 218.796 229.415 147.838 1.00 43.35  ? 574 PHE B CD1 1 
ATOM   10665 C  CD2 . PHE B 1 574 ? 219.096 227.068 147.837 1.00 43.35  ? 574 PHE B CD2 1 
ATOM   10666 C  CE1 . PHE B 1 574 ? 217.432 229.244 147.845 1.00 43.35  ? 574 PHE B CE1 1 
ATOM   10667 C  CE2 . PHE B 1 574 ? 217.729 226.892 147.847 1.00 43.35  ? 574 PHE B CE2 1 
ATOM   10668 C  CZ  . PHE B 1 574 ? 216.898 227.982 147.851 1.00 43.35  ? 574 PHE B CZ  1 
ATOM   10669 N  N   . ALA B 1 575 ? 223.932 227.750 149.371 1.00 51.26  ? 575 ALA B N   1 
ATOM   10670 C  CA  . ALA B 1 575 ? 225.371 227.712 149.170 1.00 51.26  ? 575 ALA B CA  1 
ATOM   10671 C  C   . ALA B 1 575 ? 225.753 227.594 147.704 1.00 51.26  ? 575 ALA B C   1 
ATOM   10672 O  O   . ALA B 1 575 ? 226.898 227.899 147.358 1.00 51.26  ? 575 ALA B O   1 
ATOM   10673 C  CB  . ALA B 1 575 ? 225.980 226.554 149.957 1.00 51.26  ? 575 ALA B CB  1 
ATOM   10674 N  N   . GLU B 1 576 ? 224.833 227.161 146.838 1.00 55.33  ? 576 GLU B N   1 
ATOM   10675 C  CA  . GLU B 1 576 ? 225.139 226.915 145.435 1.00 55.33  ? 576 GLU B CA  1 
ATOM   10676 C  C   . GLU B 1 576 ? 224.534 227.951 144.494 1.00 55.33  ? 576 GLU B C   1 
ATOM   10677 O  O   . GLU B 1 576 ? 225.268 228.621 143.763 1.00 55.33  ? 576 GLU B O   1 
ATOM   10678 C  CB  . GLU B 1 576 ? 224.661 225.511 145.056 1.00 55.33  ? 576 GLU B CB  1 
ATOM   10679 C  CG  . GLU B 1 576 ? 225.252 224.416 145.913 1.00 55.33  ? 576 GLU B CG  1 
ATOM   10680 C  CD  . GLU B 1 576 ? 226.637 224.002 145.463 1.00 55.33  ? 576 GLU B CD  1 
ATOM   10681 O  OE1 . GLU B 1 576 ? 227.396 224.863 144.972 1.00 55.33  ? 576 GLU B OE1 1 
ATOM   10682 O  OE2 . GLU B 1 576 ? 226.966 222.804 145.592 1.00 55.33  ? 576 GLU B OE2 1 
ATOM   10683 N  N   . THR B 1 577 ? 223.208 228.111 144.490 1.00 50.18  ? 577 THR B N   1 
ATOM   10684 C  CA  . THR B 1 577 ? 222.579 229.030 143.548 1.00 50.18  ? 577 THR B CA  1 
ATOM   10685 C  C   . THR B 1 577 ? 222.739 230.484 143.955 1.00 50.18  ? 577 THR B C   1 
ATOM   10686 O  O   . THR B 1 577 ? 222.813 231.352 143.081 1.00 50.18  ? 577 THR B O   1 
ATOM   10687 C  CB  . THR B 1 577 ? 221.097 228.704 143.387 1.00 50.18  ? 577 THR B CB  1 
ATOM   10688 O  OG1 . THR B 1 577 ? 220.425 228.909 144.634 1.00 50.18  ? 577 THR B OG1 1 
ATOM   10689 C  CG2 . THR B 1 577 ? 220.925 227.264 142.960 1.00 50.18  ? 577 THR B CG2 1 
ATOM   10690 N  N   . GLY B 1 578 ? 222.789 230.770 145.252 1.00 49.00  ? 578 GLY B N   1 
ATOM   10691 C  CA  . GLY B 1 578 ? 223.106 232.092 145.739 1.00 49.00  ? 578 GLY B CA  1 
ATOM   10692 C  C   . GLY B 1 578 ? 221.925 232.971 146.078 1.00 49.00  ? 578 GLY B C   1 
ATOM   10693 O  O   . GLY B 1 578 ? 222.120 234.030 146.684 1.00 49.00  ? 578 GLY B O   1 
ATOM   10694 N  N   . GLU B 1 579 ? 220.713 232.579 145.711 1.00 50.45  ? 579 GLU B N   1 
ATOM   10695 C  CA  . GLU B 1 579 ? 219.552 233.387 146.041 1.00 50.45  ? 579 GLU B CA  1 
ATOM   10696 C  C   . GLU B 1 579 ? 219.248 233.305 147.534 1.00 50.45  ? 579 GLU B C   1 
ATOM   10697 O  O   . GLU B 1 579 ? 219.613 232.343 148.214 1.00 50.45  ? 579 GLU B O   1 
ATOM   10698 C  CB  . GLU B 1 579 ? 218.340 232.936 145.231 1.00 50.45  ? 579 GLU B CB  1 
ATOM   10699 C  CG  . GLU B 1 579 ? 218.309 233.459 143.803 1.00 50.45  ? 579 GLU B CG  1 
ATOM   10700 C  CD  . GLU B 1 579 ? 219.544 233.076 143.011 1.00 50.45  ? 579 GLU B CD  1 
ATOM   10701 O  OE1 . GLU B 1 579 ? 219.985 231.913 143.120 1.00 50.45  ? 579 GLU B OE1 1 
ATOM   10702 O  OE2 . GLU B 1 579 ? 220.074 233.938 142.277 1.00 50.45  ? 579 GLU B OE2 1 
ATOM   10703 N  N   . LEU B 1 580 ? 218.583 234.339 148.044 1.00 49.98  ? 580 LEU B N   1 
ATOM   10704 C  CA  . LEU B 1 580 ? 218.169 234.356 149.442 1.00 49.98  ? 580 LEU B CA  1 
ATOM   10705 C  C   . LEU B 1 580 ? 217.079 233.323 149.673 1.00 49.98  ? 580 LEU B C   1 
ATOM   10706 O  O   . LEU B 1 580 ? 215.972 233.454 149.143 1.00 49.98  ? 580 LEU B O   1 
ATOM   10707 C  CB  . LEU B 1 580 ? 217.655 235.742 149.823 1.00 49.98  ? 580 LEU B CB  1 
ATOM   10708 C  CG  . LEU B 1 580 ? 218.610 236.722 150.502 1.00 49.98  ? 580 LEU B CG  1 
ATOM   10709 C  CD1 . LEU B 1 580 ? 219.000 236.227 151.882 1.00 49.98  ? 580 LEU B CD1 1 
ATOM   10710 C  CD2 . LEU B 1 580 ? 219.843 236.968 149.644 1.00 49.98  ? 580 LEU B CD2 1 
ATOM   10711 N  N   . TYR B 1 581 ? 217.384 232.296 150.467 1.00 46.79  ? 581 TYR B N   1 
ATOM   10712 C  CA  . TYR B 1 581 ? 216.344 231.349 150.845 1.00 46.79  ? 581 TYR B CA  1 
ATOM   10713 C  C   . TYR B 1 581 ? 215.396 231.920 151.891 1.00 46.79  ? 581 TYR B C   1 
ATOM   10714 O  O   . TYR B 1 581 ? 214.266 231.439 152.016 1.00 46.79  ? 581 TYR B O   1 
ATOM   10715 C  CB  . TYR B 1 581 ? 216.963 230.047 151.356 1.00 46.79  ? 581 TYR B CB  1 
ATOM   10716 C  CG  . TYR B 1 581 ? 215.959 229.119 151.988 1.00 46.79  ? 581 TYR B CG  1 
ATOM   10717 C  CD1 . TYR B 1 581 ? 214.865 228.663 151.279 1.00 46.79  ? 581 TYR B CD1 1 
ATOM   10718 C  CD2 . TYR B 1 581 ? 216.099 228.714 153.303 1.00 46.79  ? 581 TYR B CD2 1 
ATOM   10719 C  CE1 . TYR B 1 581 ? 213.940 227.830 151.861 1.00 46.79  ? 581 TYR B CE1 1 
ATOM   10720 C  CE2 . TYR B 1 581 ? 215.183 227.878 153.889 1.00 46.79  ? 581 TYR B CE2 1 
ATOM   10721 C  CZ  . TYR B 1 581 ? 214.107 227.441 153.166 1.00 46.79  ? 581 TYR B CZ  1 
ATOM   10722 O  OH  . TYR B 1 581 ? 213.188 226.603 153.751 1.00 46.79  ? 581 TYR B OH  1 
ATOM   10723 N  N   . GLY B 1 582 ? 215.816 232.942 152.626 1.00 50.08  ? 582 GLY B N   1 
ATOM   10724 C  CA  . GLY B 1 582 ? 214.947 233.558 153.606 1.00 50.08  ? 582 GLY B CA  1 
ATOM   10725 C  C   . GLY B 1 582 ? 215.750 234.400 154.576 1.00 50.08  ? 582 GLY B C   1 
ATOM   10726 O  O   . GLY B 1 582 ? 216.965 234.549 154.441 1.00 50.08  ? 582 GLY B O   1 
ATOM   10727 N  N   . ILE B 1 583 ? 215.041 234.952 155.558 1.00 45.95  ? 583 ILE B N   1 
ATOM   10728 C  CA  . ILE B 1 583 ? 215.663 235.742 156.609 1.00 45.95  ? 583 ILE B CA  1 
ATOM   10729 C  C   . ILE B 1 583 ? 215.071 235.333 157.950 1.00 45.95  ? 583 ILE B C   1 
ATOM   10730 O  O   . ILE B 1 583 ? 214.046 234.657 158.022 1.00 45.95  ? 583 ILE B O   1 
ATOM   10731 C  CB  . ILE B 1 583 ? 215.495 237.252 156.380 1.00 45.95  ? 583 ILE B CB  1 
ATOM   10732 C  CG1 . ILE B 1 583 ? 214.056 237.564 155.978 1.00 45.95  ? 583 ILE B CG1 1 
ATOM   10733 C  CG2 . ILE B 1 583 ? 216.489 237.735 155.340 1.00 45.95  ? 583 ILE B CG2 1 
ATOM   10734 C  CD1 . ILE B 1 583 ? 213.676 239.008 156.190 1.00 45.95  ? 583 ILE B CD1 1 
ATOM   10735 N  N   . GLU B 1 584 ? 215.740 235.742 159.025 1.00 44.11  ? 584 GLU B N   1 
ATOM   10736 C  CA  . GLU B 1 584 ? 215.319 235.403 160.375 1.00 44.11  ? 584 GLU B CA  1 
ATOM   10737 C  C   . GLU B 1 584 ? 215.183 236.670 161.198 1.00 44.11  ? 584 GLU B C   1 
ATOM   10738 O  O   . GLU B 1 584 ? 215.941 237.624 161.020 1.00 44.11  ? 584 GLU B O   1 
ATOM   10739 C  CB  . GLU B 1 584 ? 216.309 234.454 161.048 1.00 44.11  ? 584 GLU B CB  1 
ATOM   10740 C  CG  . GLU B 1 584 ? 215.833 233.880 162.366 1.00 44.11  ? 584 GLU B CG  1 
ATOM   10741 C  CD  . GLU B 1 584 ? 216.913 233.092 163.081 1.00 44.11  ? 584 GLU B CD  1 
ATOM   10742 O  OE1 . GLU B 1 584 ? 217.846 232.612 162.403 1.00 44.11  ? 584 GLU B OE1 1 
ATOM   10743 O  OE2 . GLU B 1 584 ? 216.831 232.957 164.319 1.00 44.11  ? 584 GLU B OE2 1 
ATOM   10744 N  N   . ALA B 1 585 ? 214.216 236.673 162.106 1.00 40.23  ? 585 ALA B N   1 
ATOM   10745 C  CA  . ALA B 1 585 ? 213.964 237.814 162.973 1.00 40.23  ? 585 ALA B CA  1 
ATOM   10746 C  C   . ALA B 1 585 ? 214.624 237.573 164.322 1.00 40.23  ? 585 ALA B C   1 
ATOM   10747 O  O   . ALA B 1 585 ? 214.331 236.579 164.992 1.00 40.23  ? 585 ALA B O   1 
ATOM   10748 C  CB  . ALA B 1 585 ? 212.464 238.051 163.142 1.00 40.23  ? 585 ALA B CB  1 
ATOM   10749 N  N   . LEU B 1 586 ? 215.510 238.478 164.717 1.00 38.82  ? 586 LEU B N   1 
ATOM   10750 C  CA  . LEU B 1 586 ? 216.277 238.354 165.947 1.00 38.82  ? 586 LEU B CA  1 
ATOM   10751 C  C   . LEU B 1 586 ? 215.974 239.536 166.853 1.00 38.82  ? 586 LEU B C   1 
ATOM   10752 O  O   . LEU B 1 586 ? 216.117 240.690 166.436 1.00 38.82  ? 586 LEU B O   1 
ATOM   10753 C  CB  . LEU B 1 586 ? 217.773 238.294 165.645 1.00 38.82  ? 586 LEU B CB  1 
ATOM   10754 C  CG  . LEU B 1 586 ? 218.406 236.952 165.290 1.00 38.82  ? 586 LEU B CG  1 
ATOM   10755 C  CD1 . LEU B 1 586 ? 217.911 236.445 163.954 1.00 38.82  ? 586 LEU B CD1 1 
ATOM   10756 C  CD2 . LEU B 1 586 ? 219.916 237.074 165.281 1.00 38.82  ? 586 LEU B CD2 1 
ATOM   10757 N  N   . ALA B 1 587 ? 215.578 239.253 168.090 1.00 35.66  ? 587 ALA B N   1 
ATOM   10758 C  CA  . ALA B 1 587 ? 215.221 240.314 169.018 1.00 35.66  ? 587 ALA B CA  1 
ATOM   10759 C  C   . ALA B 1 587 ? 216.449 241.121 169.416 1.00 35.66  ? 587 ALA B C   1 
ATOM   10760 O  O   . ALA B 1 587 ? 217.545 240.590 169.597 1.00 35.66  ? 587 ALA B O   1 
ATOM   10761 C  CB  . ALA B 1 587 ? 214.551 239.737 170.262 1.00 35.66  ? 587 ALA B CB  1 
ATOM   10762 N  N   . ARG B 1 588 ? 216.251 242.428 169.551 1.00 36.40  ? 588 ARG B N   1 
ATOM   10763 C  CA  . ARG B 1 588 ? 217.312 243.331 169.965 1.00 36.40  ? 588 ARG B CA  1 
ATOM   10764 C  C   . ARG B 1 588 ? 216.712 244.361 170.910 1.00 36.40  ? 588 ARG B C   1 
ATOM   10765 O  O   . ARG B 1 588 ? 215.502 244.599 170.902 1.00 36.40  ? 588 ARG B O   1 
ATOM   10766 C  CB  . ARG B 1 588 ? 217.974 243.996 168.759 1.00 36.40  ? 588 ARG B CB  1 
ATOM   10767 C  CG  . ARG B 1 588 ? 218.800 243.053 167.890 1.00 36.40  ? 588 ARG B CG  1 
ATOM   10768 C  CD  . ARG B 1 588 ? 219.922 242.396 168.662 1.00 36.40  ? 588 ARG B CD  1 
ATOM   10769 N  NE  . ARG B 1 588 ? 220.728 241.521 167.817 1.00 36.40  ? 588 ARG B NE  1 
ATOM   10770 C  CZ  . ARG B 1 588 ? 221.056 240.272 168.120 1.00 36.40  ? 588 ARG B CZ  1 
ATOM   10771 N  NH1 . ARG B 1 588 ? 220.677 239.713 169.256 1.00 36.40  ? 588 ARG B NH1 1 
ATOM   10772 N  NH2 . ARG B 1 588 ? 221.789 239.567 167.264 1.00 36.40  ? 588 ARG B NH2 1 
ATOM   10773 N  N   . TRP B 1 589 ? 217.568 244.970 171.726 1.00 39.26  ? 589 TRP B N   1 
ATOM   10774 C  CA  . TRP B 1 589 ? 217.096 245.742 172.873 1.00 39.26  ? 589 TRP B CA  1 
ATOM   10775 C  C   . TRP B 1 589 ? 218.162 246.748 173.267 1.00 39.26  ? 589 TRP B C   1 
ATOM   10776 O  O   . TRP B 1 589 ? 219.201 246.361 173.806 1.00 39.26  ? 589 TRP B O   1 
ATOM   10777 C  CB  . TRP B 1 589 ? 216.778 244.791 174.025 1.00 39.26  ? 589 TRP B CB  1 
ATOM   10778 C  CG  . TRP B 1 589 ? 216.619 245.378 175.403 1.00 39.26  ? 589 TRP B CG  1 
ATOM   10779 C  CD1 . TRP B 1 589 ? 217.156 244.889 176.560 1.00 39.26  ? 589 TRP B CD1 1 
ATOM   10780 C  CD2 . TRP B 1 589 ? 215.831 246.508 175.780 1.00 39.26  ? 589 TRP B CD2 1 
ATOM   10781 N  NE1 . TRP B 1 589 ? 216.772 245.657 177.623 1.00 39.26  ? 589 TRP B NE1 1 
ATOM   10782 C  CE2 . TRP B 1 589 ? 215.955 246.656 177.170 1.00 39.26  ? 589 TRP B CE2 1 
ATOM   10783 C  CE3 . TRP B 1 589 ? 215.045 247.416 175.076 1.00 39.26  ? 589 TRP B CE3 1 
ATOM   10784 C  CZ2 . TRP B 1 589 ? 215.333 247.673 177.861 1.00 39.26  ? 589 TRP B CZ2 1 
ATOM   10785 C  CZ3 . TRP B 1 589 ? 214.427 248.420 175.767 1.00 39.26  ? 589 TRP B CZ3 1 
ATOM   10786 C  CH2 . TRP B 1 589 ? 214.571 248.542 177.144 1.00 39.26  ? 589 TRP B CH2 1 
ATOM   10787 N  N   . HIS B 1 590 ? 217.907 248.029 173.009 1.00 51.32  ? 590 HIS B N   1 
ATOM   10788 C  CA  . HIS B 1 590 ? 218.861 249.093 173.311 1.00 51.32  ? 590 HIS B CA  1 
ATOM   10789 C  C   . HIS B 1 590 ? 218.162 250.184 174.103 1.00 51.32  ? 590 HIS B C   1 
ATOM   10790 O  O   . HIS B 1 590 ? 217.051 250.591 173.753 1.00 51.32  ? 590 HIS B O   1 
ATOM   10791 C  CB  . HIS B 1 590 ? 219.470 249.674 172.035 1.00 51.32  ? 590 HIS B CB  1 
ATOM   10792 C  CG  . HIS B 1 590 ? 220.258 250.925 172.263 1.00 51.32  ? 590 HIS B CG  1 
ATOM   10793 N  ND1 . HIS B 1 590 ? 221.572 250.911 172.677 1.00 51.32  ? 590 HIS B ND1 1 
ATOM   10794 C  CD2 . HIS B 1 590 ? 219.918 252.228 172.130 1.00 51.32  ? 590 HIS B CD2 1 
ATOM   10795 C  CE1 . HIS B 1 590 ? 222.008 252.152 172.791 1.00 51.32  ? 590 HIS B CE1 1 
ATOM   10796 N  NE2 . HIS B 1 590 ? 221.024 252.971 172.465 1.00 51.32  ? 590 HIS B NE2 1 
ATOM   10797 N  N   . ASP B 1 591 ? 218.821 250.665 175.155 1.00 53.86  ? 591 ASP B N   1 
ATOM   10798 C  CA  . ASP B 1 591 ? 218.236 251.612 176.090 1.00 53.86  ? 591 ASP B CA  1 
ATOM   10799 C  C   . ASP B 1 591 ? 219.307 252.611 176.508 1.00 53.86  ? 591 ASP B C   1 
ATOM   10800 O  O   . ASP B 1 591 ? 220.404 252.200 176.926 1.00 53.86  ? 591 ASP B O   1 
ATOM   10801 C  CB  . ASP B 1 591 ? 217.679 250.879 177.315 1.00 53.86  ? 591 ASP B CB  1 
ATOM   10802 C  CG  . ASP B 1 591 ? 216.684 251.709 178.096 1.00 53.86  ? 591 ASP B CG  1 
ATOM   10803 O  OD1 . ASP B 1 591 ? 216.387 252.844 177.679 1.00 53.86  ? 591 ASP B OD1 1 
ATOM   10804 O  OD2 . ASP B 1 591 ? 216.196 251.223 179.138 1.00 53.86  ? 591 ASP B OD2 1 
ATOM   10805 N  N   . PRO B 1 592 ? 219.046 253.917 176.403 1.00 52.36  ? 592 PRO B N   1 
ATOM   10806 C  CA  . PRO B 1 592 ? 220.069 254.900 176.799 1.00 52.36  ? 592 PRO B CA  1 
ATOM   10807 C  C   . PRO B 1 592 ? 220.538 254.766 178.236 1.00 52.36  ? 592 PRO B C   1 
ATOM   10808 O  O   . PRO B 1 592 ? 221.718 255.008 178.518 1.00 52.36  ? 592 PRO B O   1 
ATOM   10809 C  CB  . PRO B 1 592 ? 219.369 256.246 176.557 1.00 52.36  ? 592 PRO B CB  1 
ATOM   10810 C  CG  . PRO B 1 592 ? 217.932 255.920 176.288 1.00 52.36  ? 592 PRO B CG  1 
ATOM   10811 C  CD  . PRO B 1 592 ? 217.924 254.557 175.706 1.00 52.36  ? 592 PRO B CD  1 
ATOM   10812 N  N   . LEU B 1 593 ? 219.657 254.388 179.157 1.00 49.89  ? 593 LEU B N   1 
ATOM   10813 C  CA  . LEU B 1 593 ? 220.059 254.312 180.553 1.00 49.89  ? 593 LEU B CA  1 
ATOM   10814 C  C   . LEU B 1 593 ? 220.853 253.054 180.879 1.00 49.89  ? 593 LEU B C   1 
ATOM   10815 O  O   . LEU B 1 593 ? 221.492 253.010 181.935 1.00 49.89  ? 593 LEU B O   1 
ATOM   10816 C  CB  . LEU B 1 593 ? 218.830 254.390 181.457 1.00 49.89  ? 593 LEU B CB  1 
ATOM   10817 C  CG  . LEU B 1 593 ? 218.414 255.776 181.961 1.00 49.89  ? 593 LEU B CG  1 
ATOM   10818 C  CD1 . LEU B 1 593 ? 219.462 256.340 182.909 1.00 49.89  ? 593 LEU B CD1 1 
ATOM   10819 C  CD2 . LEU B 1 593 ? 218.153 256.736 180.808 1.00 49.89  ? 593 LEU B CD2 1 
ATOM   10820 N  N   . HIS B 1 594 ? 220.834 252.039 180.011 1.00 51.58  ? 594 HIS B N   1 
ATOM   10821 C  CA  . HIS B 1 594 ? 221.510 250.773 180.284 1.00 51.58  ? 594 HIS B CA  1 
ATOM   10822 C  C   . HIS B 1 594 ? 222.439 250.299 179.182 1.00 51.58  ? 594 HIS B C   1 
ATOM   10823 O  O   . HIS B 1 594 ? 223.273 249.425 179.447 1.00 51.58  ? 594 HIS B O   1 
ATOM   10824 C  CB  . HIS B 1 594 ? 220.490 249.657 180.545 1.00 51.58  ? 594 HIS B CB  1 
ATOM   10825 C  CG  . HIS B 1 594 ? 219.387 250.049 181.471 1.00 51.58  ? 594 HIS B CG  1 
ATOM   10826 N  ND1 . HIS B 1 594 ? 218.234 250.661 181.033 1.00 51.58  ? 594 HIS B ND1 1 
ATOM   10827 C  CD2 . HIS B 1 594 ? 219.252 249.902 182.808 1.00 51.58  ? 594 HIS B CD2 1 
ATOM   10828 C  CE1 . HIS B 1 594 ? 217.439 250.884 182.064 1.00 51.58  ? 594 HIS B CE1 1 
ATOM   10829 N  NE2 . HIS B 1 594 ? 218.033 250.432 183.153 1.00 51.58  ? 594 HIS B NE2 1 
ATOM   10830 N  N   . GLY B 1 595 ? 222.325 250.819 177.967 1.00 50.61  ? 595 GLY B N   1 
ATOM   10831 C  CA  . GLY B 1 595 ? 223.123 250.328 176.865 1.00 50.61  ? 595 GLY B CA  1 
ATOM   10832 C  C   . GLY B 1 595 ? 222.522 249.086 176.240 1.00 50.61  ? 595 GLY B C   1 
ATOM   10833 O  O   . GLY B 1 595 ? 221.442 248.619 176.599 1.00 50.61  ? 595 GLY B O   1 
ATOM   10834 N  N   . HIS B 1 596 ? 223.253 248.541 175.274 1.00 44.30  ? 596 HIS B N   1 
ATOM   10835 C  CA  . HIS B 1 596 ? 222.794 247.354 174.569 1.00 44.30  ? 596 HIS B CA  1 
ATOM   10836 C  C   . HIS B 1 596 ? 222.816 246.154 175.500 1.00 44.30  ? 596 HIS B C   1 
ATOM   10837 O  O   . HIS B 1 596 ? 223.820 245.898 176.171 1.00 44.30  ? 596 HIS B O   1 
ATOM   10838 C  CB  . HIS B 1 596 ? 223.674 247.100 173.349 1.00 44.30  ? 596 HIS B CB  1 
ATOM   10839 C  CG  . HIS B 1 596 ? 223.439 248.062 172.229 1.00 44.30  ? 596 HIS B CG  1 
ATOM   10840 N  ND1 . HIS B 1 596 ? 222.380 247.943 171.357 1.00 44.30  ? 596 HIS B ND1 1 
ATOM   10841 C  CD2 . HIS B 1 596 ? 224.123 249.163 171.842 1.00 44.30  ? 596 HIS B CD2 1 
ATOM   10842 C  CE1 . HIS B 1 596 ? 222.423 248.927 170.478 1.00 44.30  ? 596 HIS B CE1 1 
ATOM   10843 N  NE2 . HIS B 1 596 ? 223.471 249.682 170.750 1.00 44.30  ? 596 HIS B NE2 1 
ATOM   10844 N  N   . VAL B 1 597 ? 221.710 245.420 175.542 1.00 35.60  ? 597 VAL B N   1 
ATOM   10845 C  CA  . VAL B 1 597 ? 221.586 244.205 176.336 1.00 35.60  ? 597 VAL B CA  1 
ATOM   10846 C  C   . VAL B 1 597 ? 221.203 243.076 175.392 1.00 35.60  ? 597 VAL B C   1 
ATOM   10847 O  O   . VAL B 1 597 ? 220.277 243.237 174.596 1.00 35.60  ? 597 VAL B O   1 
ATOM   10848 C  CB  . VAL B 1 597 ? 220.547 244.338 177.462 1.00 35.60  ? 597 VAL B CB  1 
ATOM   10849 C  CG1 . VAL B 1 597 ? 220.585 243.118 178.358 1.00 35.60  ? 597 VAL B CG1 1 
ATOM   10850 C  CG2 . VAL B 1 597 ? 220.801 245.598 178.265 1.00 35.60  ? 597 VAL B CG2 1 
ATOM   10851 N  N   . PRO B 1 598 ? 221.888 241.945 175.425 1.00 32.27  ? 598 PRO B N   1 
ATOM   10852 C  CA  . PRO B 1 598 ? 221.603 240.885 174.475 1.00 32.27  ? 598 PRO B CA  1 
ATOM   10853 C  C   . PRO B 1 598 ? 220.412 240.050 174.906 1.00 32.27  ? 598 PRO B C   1 
ATOM   10854 O  O   . PRO B 1 598 ? 220.077 239.979 176.102 1.00 32.27  ? 598 PRO B O   1 
ATOM   10855 C  CB  . PRO B 1 598 ? 222.895 240.058 174.487 1.00 32.27  ? 598 PRO B CB  1 
ATOM   10856 C  CG  . PRO B 1 598 ? 223.420 240.246 175.855 1.00 32.27  ? 598 PRO B CG  1 
ATOM   10857 C  CD  . PRO B 1 598 ? 223.074 241.653 176.242 1.00 32.27  ? 598 PRO B CD  1 
ATOM   10858 N  N   . PRO B 1 599 ? 219.750 239.395 173.952 1.00 29.68  ? 599 PRO B N   1 
ATOM   10859 C  CA  . PRO B 1 599 ? 218.642 238.501 174.305 1.00 29.68  ? 599 PRO B CA  1 
ATOM   10860 C  C   . PRO B 1 599 ? 219.049 237.389 175.236 1.00 29.68  ? 599 PRO B C   1 
ATOM   10861 O  O   . PRO B 1 599 ? 218.259 237.017 176.113 1.00 29.68  ? 599 PRO B O   1 
ATOM   10862 C  CB  . PRO B 1 599 ? 218.183 237.966 172.945 1.00 29.68  ? 599 PRO B CB  1 
ATOM   10863 C  CG  . PRO B 1 599 ? 219.354 238.152 172.059 1.00 29.68  ? 599 PRO B CG  1 
ATOM   10864 C  CD  . PRO B 1 599 ? 219.980 239.426 172.505 1.00 29.68  ? 599 PRO B CD  1 
ATOM   10865 N  N   . SER B 1 600 ? 220.275 236.886 175.104 1.00 32.09  ? 600 SER B N   1 
ATOM   10866 C  CA  . SER B 1 600 ? 220.749 235.822 175.976 1.00 32.09  ? 600 SER B CA  1 
ATOM   10867 C  C   . SER B 1 600 ? 220.716 236.233 177.435 1.00 32.09  ? 600 SER B C   1 
ATOM   10868 O  O   . SER B 1 600 ? 220.709 235.364 178.312 1.00 32.09  ? 600 SER B O   1 
ATOM   10869 C  CB  . SER B 1 600 ? 222.168 235.411 175.584 1.00 32.09  ? 600 SER B CB  1 
ATOM   10870 O  OG  . SER B 1 600 ? 223.061 236.506 175.692 1.00 32.09  ? 600 SER B OG  1 
ATOM   10871 N  N   . ARG B 1 601 ? 220.700 237.531 177.717 1.00 33.91  ? 601 ARG B N   1 
ATOM   10872 C  CA  . ARG B 1 601 ? 220.459 238.004 179.070 1.00 33.91  ? 601 ARG B CA  1 
ATOM   10873 C  C   . ARG B 1 601 ? 219.013 238.412 179.319 1.00 33.91  ? 601 ARG B C   1 
ATOM   10874 O  O   . ARG B 1 601 ? 218.457 238.046 180.359 1.00 33.91  ? 601 ARG B O   1 
ATOM   10875 C  CB  . ARG B 1 601 ? 221.370 239.184 179.406 1.00 33.91  ? 601 ARG B CB  1 
ATOM   10876 C  CG  . ARG B 1 601 ? 221.158 239.711 180.811 1.00 33.91  ? 601 ARG B CG  1 
ATOM   10877 C  CD  . ARG B 1 601 ? 222.399 240.396 181.326 1.00 33.91  ? 601 ARG B CD  1 
ATOM   10878 N  NE  . ARG B 1 601 ? 222.516 241.754 180.817 1.00 33.91  ? 601 ARG B NE  1 
ATOM   10879 C  CZ  . ARG B 1 601 ? 222.514 242.836 181.581 1.00 33.91  ? 601 ARG B CZ  1 
ATOM   10880 N  NH1 . ARG B 1 601 ? 222.410 242.751 182.897 1.00 33.91  ? 601 ARG B NH1 1 
ATOM   10881 N  NH2 . ARG B 1 601 ? 222.622 244.033 181.012 1.00 33.91  ? 601 ARG B NH2 1 
ATOM   10882 N  N   . PHE B 1 602 ? 218.369 239.157 178.415 1.00 33.30  ? 602 PHE B N   1 
ATOM   10883 C  CA  . PHE B 1 602 ? 217.096 239.739 178.824 1.00 33.30  ? 602 PHE B CA  1 
ATOM   10884 C  C   . PHE B 1 602 ? 215.881 238.873 178.513 1.00 33.30  ? 602 PHE B C   1 
ATOM   10885 O  O   . PHE B 1 602 ? 214.767 239.280 178.852 1.00 33.30  ? 602 PHE B O   1 
ATOM   10886 C  CB  . PHE B 1 602 ? 216.885 241.137 178.227 1.00 33.30  ? 602 PHE B CB  1 
ATOM   10887 C  CG  . PHE B 1 602 ? 216.505 241.158 176.780 1.00 33.30  ? 602 PHE B CG  1 
ATOM   10888 C  CD1 . PHE B 1 602 ? 217.449 241.344 175.800 1.00 33.30  ? 602 PHE B CD1 1 
ATOM   10889 C  CD2 . PHE B 1 602 ? 215.186 241.056 176.403 1.00 33.30  ? 602 PHE B CD2 1 
ATOM   10890 C  CE1 . PHE B 1 602 ? 217.077 241.391 174.472 1.00 33.30  ? 602 PHE B CE1 1 
ATOM   10891 C  CE2 . PHE B 1 602 ? 214.820 241.087 175.084 1.00 33.30  ? 602 PHE B CE2 1 
ATOM   10892 C  CZ  . PHE B 1 602 ? 215.762 241.256 174.120 1.00 33.30  ? 602 PHE B CZ  1 
ATOM   10893 N  N   . ILE B 1 603 ? 216.037 237.705 177.899 1.00 35.89  ? 603 ILE B N   1 
ATOM   10894 C  CA  . ILE B 1 603 ? 214.895 236.800 177.776 1.00 35.89  ? 603 ILE B CA  1 
ATOM   10895 C  C   . ILE B 1 603 ? 214.703 236.043 179.088 1.00 35.89  ? 603 ILE B C   1 
ATOM   10896 O  O   . ILE B 1 603 ? 213.554 235.864 179.521 1.00 35.89  ? 603 ILE B O   1 
ATOM   10897 C  CB  . ILE B 1 603 ? 215.040 235.849 176.580 1.00 35.89  ? 603 ILE B CB  1 
ATOM   10898 C  CG1 . ILE B 1 603 ? 214.699 236.586 175.290 1.00 35.89  ? 603 ILE B CG1 1 
ATOM   10899 C  CG2 . ILE B 1 603 ? 214.123 234.666 176.728 1.00 35.89  ? 603 ILE B CG2 1 
ATOM   10900 C  CD1 . ILE B 1 603 ? 213.278 237.073 175.240 1.00 35.89  ? 603 ILE B CD1 1 
ATOM   10901 N  N   . PRO B 1 604 ? 215.764 235.582 179.762 1.00 37.03  ? 604 PRO B N   1 
ATOM   10902 C  CA  . PRO B 1 604 ? 215.553 235.066 181.122 1.00 37.03  ? 604 PRO B CA  1 
ATOM   10903 C  C   . PRO B 1 604 ? 214.912 236.085 182.039 1.00 37.03  ? 604 PRO B C   1 
ATOM   10904 O  O   . PRO B 1 604 ? 214.107 235.723 182.906 1.00 37.03  ? 604 PRO B O   1 
ATOM   10905 C  CB  . PRO B 1 604 ? 216.968 234.696 181.575 1.00 37.03  ? 604 PRO B CB  1 
ATOM   10906 C  CG  . PRO B 1 604 ? 217.653 234.339 180.335 1.00 37.03  ? 604 PRO B CG  1 
ATOM   10907 C  CD  . PRO B 1 604 ? 217.125 235.273 179.288 1.00 37.03  ? 604 PRO B CD  1 
ATOM   10908 N  N   . LEU B 1 605 ? 215.244 237.361 181.862 1.00 40.64  ? 605 LEU B N   1 
ATOM   10909 C  CA  . LEU B 1 605 ? 214.637 238.396 182.685 1.00 40.64  ? 605 LEU B CA  1 
ATOM   10910 C  C   . LEU B 1 605 ? 213.144 238.504 182.406 1.00 40.64  ? 605 LEU B C   1 
ATOM   10911 O  O   . LEU B 1 605 ? 212.343 238.667 183.333 1.00 40.64  ? 605 LEU B O   1 
ATOM   10912 C  CB  . LEU B 1 605 ? 215.338 239.728 182.436 1.00 40.64  ? 605 LEU B CB  1 
ATOM   10913 C  CG  . LEU B 1 605 ? 214.954 240.873 183.357 1.00 40.64  ? 605 LEU B CG  1 
ATOM   10914 C  CD1 . LEU B 1 605 ? 215.360 240.508 184.759 1.00 40.64  ? 605 LEU B CD1 1 
ATOM   10915 C  CD2 . LEU B 1 605 ? 215.639 242.138 182.919 1.00 40.64  ? 605 LEU B CD2 1 
ATOM   10916 N  N   . ALA B 1 606 ? 212.750 238.406 181.136 1.00 43.93  ? 606 ALA B N   1 
ATOM   10917 C  CA  . ALA B 1 606 ? 211.331 238.435 180.802 1.00 43.93  ? 606 ALA B CA  1 
ATOM   10918 C  C   . ALA B 1 606 ? 210.608 237.217 181.360 1.00 43.93  ? 606 ALA B C   1 
ATOM   10919 O  O   . ALA B 1 606 ? 209.465 237.324 181.815 1.00 43.93  ? 606 ALA B O   1 
ATOM   10920 C  CB  . ALA B 1 606 ? 211.148 238.525 179.289 1.00 43.93  ? 606 ALA B CB  1 
ATOM   10921 N  N   . GLU B 1 607 ? 211.251 236.048 181.323 1.00 46.05  ? 607 GLU B N   1 
ATOM   10922 C  CA  . GLU B 1 607 ? 210.646 234.854 181.903 1.00 46.05  ? 607 GLU B CA  1 
ATOM   10923 C  C   . GLU B 1 607 ? 210.478 234.981 183.410 1.00 46.05  ? 607 GLU B C   1 
ATOM   10924 O  O   . GLU B 1 607 ? 209.476 234.515 183.961 1.00 46.05  ? 607 GLU B O   1 
ATOM   10925 C  CB  . GLU B 1 607 ? 211.487 233.624 181.568 1.00 46.05  ? 607 GLU B CB  1 
ATOM   10926 C  CG  . GLU B 1 607 ? 210.799 232.295 181.847 1.00 46.05  ? 607 GLU B CG  1 
ATOM   10927 C  CD  . GLU B 1 607 ? 211.053 231.786 183.253 1.00 46.05  ? 607 GLU B CD  1 
ATOM   10928 O  OE1 . GLU B 1 607 ? 212.112 232.120 183.824 1.00 46.05  ? 607 GLU B OE1 1 
ATOM   10929 O  OE2 . GLU B 1 607 ? 210.194 231.052 183.786 1.00 46.05  ? 607 GLU B OE2 1 
ATOM   10930 N  N   . GLU B 1 608 ? 211.450 235.585 184.095 1.00 46.53  ? 608 GLU B N   1 
ATOM   10931 C  CA  . GLU B 1 608 ? 211.359 235.754 185.540 1.00 46.53  ? 608 GLU B CA  1 
ATOM   10932 C  C   . GLU B 1 608 ? 210.442 236.900 185.953 1.00 46.53  ? 608 GLU B C   1 
ATOM   10933 O  O   . GLU B 1 608 ? 209.996 236.932 187.103 1.00 46.53  ? 608 GLU B O   1 
ATOM   10934 C  CB  . GLU B 1 608 ? 212.753 235.968 186.128 1.00 46.53  ? 608 GLU B CB  1 
ATOM   10935 C  CG  . GLU B 1 608 ? 212.828 235.782 187.628 1.00 46.53  ? 608 GLU B CG  1 
ATOM   10936 C  CD  . GLU B 1 608 ? 212.011 234.600 188.106 1.00 46.53  ? 608 GLU B CD  1 
ATOM   10937 O  OE1 . GLU B 1 608 ? 212.377 233.451 187.780 1.00 46.53  ? 608 GLU B OE1 1 
ATOM   10938 O  OE2 . GLU B 1 608 ? 211.000 234.820 188.806 1.00 46.53  ? 608 GLU B OE2 1 
ATOM   10939 N  N   . ILE B 1 609 ? 210.154 237.841 185.055 1.00 43.07  ? 609 ILE B N   1 
ATOM   10940 C  CA  . ILE B 1 609 ? 209.223 238.913 185.387 1.00 43.07  ? 609 ILE B CA  1 
ATOM   10941 C  C   . ILE B 1 609 ? 207.798 238.628 184.925 1.00 43.07  ? 609 ILE B C   1 
ATOM   10942 O  O   . ILE B 1 609 ? 206.855 239.231 185.455 1.00 43.07  ? 609 ILE B O   1 
ATOM   10943 C  CB  . ILE B 1 609 ? 209.692 240.257 184.803 1.00 43.07  ? 609 ILE B CB  1 
ATOM   10944 C  CG1 . ILE B 1 609 ? 209.043 241.417 185.549 1.00 43.07  ? 609 ILE B CG1 1 
ATOM   10945 C  CG2 . ILE B 1 609 ? 209.365 240.349 183.324 1.00 43.07  ? 609 ILE B CG2 1 
ATOM   10946 C  CD1 . ILE B 1 609 ? 209.540 242.769 185.121 1.00 43.07  ? 609 ILE B CD1 1 
ATOM   10947 N  N   . GLY B 1 610 ? 207.608 237.726 183.969 1.00 46.39  ? 610 GLY B N   1 
ATOM   10948 C  CA  . GLY B 1 610 ? 206.270 237.410 183.515 1.00 46.39  ? 610 GLY B CA  1 
ATOM   10949 C  C   . GLY B 1 610 ? 205.694 238.350 182.480 1.00 46.39  ? 610 GLY B C   1 
ATOM   10950 O  O   . GLY B 1 610 ? 204.483 238.591 182.481 1.00 46.39  ? 610 GLY B O   1 
ATOM   10951 N  N   . GLU B 1 611 ? 206.524 238.895 181.594 1.00 54.59  ? 611 GLU B N   1 
ATOM   10952 C  CA  . GLU B 1 611 ? 206.059 239.721 180.489 1.00 54.59  ? 611 GLU B CA  1 
ATOM   10953 C  C   . GLU B 1 611 ? 206.441 239.135 179.137 1.00 54.59  ? 611 GLU B C   1 
ATOM   10954 O  O   . GLU B 1 611 ? 206.497 239.865 178.143 1.00 54.59  ? 611 GLU B O   1 
ATOM   10955 C  CB  . GLU B 1 611 ? 206.611 241.140 180.625 1.00 54.59  ? 611 GLU B CB  1 
ATOM   10956 C  CG  . GLU B 1 611 ? 205.811 242.206 179.898 1.00 54.59  ? 611 GLU B CG  1 
ATOM   10957 C  CD  . GLU B 1 611 ? 204.356 242.218 180.304 1.00 54.59  ? 611 GLU B CD  1 
ATOM   10958 O  OE1 . GLU B 1 611 ? 204.016 242.914 181.284 1.00 54.59  ? 611 GLU B OE1 1 
ATOM   10959 O  OE2 . GLU B 1 611 ? 203.547 241.533 179.645 1.00 54.59  ? 611 GLU B OE2 1 
ATOM   10960 N  N   . ILE B 1 612 ? 206.694 237.829 179.071 1.00 49.93  ? 612 ILE B N   1 
ATOM   10961 C  CA  . ILE B 1 612 ? 207.296 237.257 177.874 1.00 49.93  ? 612 ILE B CA  1 
ATOM   10962 C  C   . ILE B 1 612 ? 206.257 237.079 176.776 1.00 49.93  ? 612 ILE B C   1 
ATOM   10963 O  O   . ILE B 1 612 ? 206.582 237.101 175.580 1.00 49.93  ? 612 ILE B O   1 
ATOM   10964 C  CB  . ILE B 1 612 ? 208.005 235.942 178.233 1.00 49.93  ? 612 ILE B CB  1 
ATOM   10965 C  CG1 . ILE B 1 612 ? 209.008 235.572 177.148 1.00 49.93  ? 612 ILE B CG1 1 
ATOM   10966 C  CG2 . ILE B 1 612 ? 207.010 234.830 178.455 1.00 49.93  ? 612 ILE B CG2 1 
ATOM   10967 C  CD1 . ILE B 1 612 ? 210.164 234.789 177.676 1.00 49.93  ? 612 ILE B CD1 1 
ATOM   10968 N  N   . GLU B 1 613 ? 204.990 236.926 177.156 1.00 57.82  ? 613 GLU B N   1 
ATOM   10969 C  CA  . GLU B 1 613 ? 203.938 236.803 176.157 1.00 57.82  ? 613 GLU B CA  1 
ATOM   10970 C  C   . GLU B 1 613 ? 203.838 238.067 175.323 1.00 57.82  ? 613 GLU B C   1 
ATOM   10971 O  O   . GLU B 1 613 ? 203.655 238.003 174.103 1.00 57.82  ? 613 GLU B O   1 
ATOM   10972 C  CB  . GLU B 1 613 ? 202.602 236.497 176.834 1.00 57.82  ? 613 GLU B CB  1 
ATOM   10973 C  CG  . GLU B 1 613 ? 202.576 235.177 177.588 1.00 57.82  ? 613 GLU B CG  1 
ATOM   10974 C  CD  . GLU B 1 613 ? 202.855 235.346 179.069 1.00 57.82  ? 613 GLU B CD  1 
ATOM   10975 O  OE1 . GLU B 1 613 ? 203.658 236.234 179.428 1.00 57.82  ? 613 GLU B OE1 1 
ATOM   10976 O  OE2 . GLU B 1 613 ? 202.274 234.590 179.875 1.00 57.82  ? 613 GLU B OE2 1 
ATOM   10977 N  N   . ASN B 1 614 ? 203.962 239.229 175.963 1.00 58.22  ? 614 ASN B N   1 
ATOM   10978 C  CA  . ASN B 1 614 ? 203.912 240.479 175.220 1.00 58.22  ? 614 ASN B CA  1 
ATOM   10979 C  C   . ASN B 1 614 ? 205.129 240.648 174.323 1.00 58.22  ? 614 ASN B C   1 
ATOM   10980 O  O   . ASN B 1 614 ? 205.014 241.219 173.234 1.00 58.22  ? 614 ASN B O   1 
ATOM   10981 C  CB  . ASN B 1 614 ? 203.778 241.655 176.182 1.00 58.22  ? 614 ASN B CB  1 
ATOM   10982 C  CG  . ASN B 1 614 ? 202.361 241.830 176.683 1.00 58.22  ? 614 ASN B CG  1 
ATOM   10983 O  OD1 . ASN B 1 614 ? 201.402 241.667 175.929 1.00 58.22  ? 614 ASN B OD1 1 
ATOM   10984 N  ND2 . ASN B 1 614 ? 202.218 242.169 177.957 1.00 58.22  ? 614 ASN B ND2 1 
ATOM   10985 N  N   . ILE B 1 615 ? 206.296 240.157 174.747 1.00 55.33  ? 615 ILE B N   1 
ATOM   10986 C  CA  . ILE B 1 615 ? 207.464 240.185 173.870 1.00 55.33  ? 615 ILE B CA  1 
ATOM   10987 C  C   . ILE B 1 615 ? 207.199 239.357 172.625 1.00 55.33  ? 615 ILE B C   1 
ATOM   10988 O  O   . ILE B 1 615 ? 207.525 239.765 171.502 1.00 55.33  ? 615 ILE B O   1 
ATOM   10989 C  CB  . ILE B 1 615 ? 208.715 239.693 174.618 1.00 55.33  ? 615 ILE B CB  1 
ATOM   10990 C  CG1 . ILE B 1 615 ? 209.111 240.681 175.711 1.00 55.33  ? 615 ILE B CG1 1 
ATOM   10991 C  CG2 . ILE B 1 615 ? 209.862 239.482 173.657 1.00 55.33  ? 615 ILE B CG2 1 
ATOM   10992 C  CD1 . ILE B 1 615 ? 209.945 241.833 175.213 1.00 55.33  ? 615 ILE B CD1 1 
ATOM   10993 N  N   . GLY B 1 616 ? 206.609 238.177 172.804 1.00 57.90  ? 616 GLY B N   1 
ATOM   10994 C  CA  . GLY B 1 616 ? 206.270 237.359 171.652 1.00 57.90  ? 616 GLY B CA  1 
ATOM   10995 C  C   . GLY B 1 616 ? 205.256 238.031 170.747 1.00 57.90  ? 616 GLY B C   1 
ATOM   10996 O  O   . GLY B 1 616 ? 205.367 237.989 169.517 1.00 57.90  ? 616 GLY B O   1 
ATOM   10997 N  N   . ARG B 1 617 ? 204.244 238.653 171.348 1.00 59.43  ? 617 ARG B N   1 
ATOM   10998 C  CA  . ARG B 1 617 ? 203.273 239.394 170.557 1.00 59.43  ? 617 ARG B CA  1 
ATOM   10999 C  C   . ARG B 1 617 ? 203.970 240.457 169.729 1.00 59.43  ? 617 ARG B C   1 
ATOM   11000 O  O   . ARG B 1 617 ? 203.698 240.613 168.530 1.00 59.43  ? 617 ARG B O   1 
ATOM   11001 C  CB  . ARG B 1 617 ? 202.223 240.031 171.467 1.00 59.43  ? 617 ARG B CB  1 
ATOM   11002 C  CG  . ARG B 1 617 ? 201.340 239.045 172.205 1.00 59.43  ? 617 ARG B CG  1 
ATOM   11003 C  CD  . ARG B 1 617 ? 200.137 239.741 172.823 1.00 59.43  ? 617 ARG B CD  1 
ATOM   11004 N  NE  . ARG B 1 617 ? 199.527 240.694 171.904 1.00 59.43  ? 617 ARG B NE  1 
ATOM   11005 C  CZ  . ARG B 1 617 ? 198.277 240.619 171.468 1.00 59.43  ? 617 ARG B CZ  1 
ATOM   11006 N  NH1 . ARG B 1 617 ? 197.471 239.639 171.845 1.00 59.43  ? 617 ARG B NH1 1 
ATOM   11007 N  NH2 . ARG B 1 617 ? 197.824 241.549 170.633 1.00 59.43  ? 617 ARG B NH2 1 
ATOM   11008 N  N   . TRP B 1 618 ? 204.892 241.189 170.355 1.00 55.20  ? 618 TRP B N   1 
ATOM   11009 C  CA  . TRP B 1 618 ? 205.567 242.259 169.641 1.00 55.20  ? 618 TRP B CA  1 
ATOM   11010 C  C   . TRP B 1 618 ? 206.394 241.716 168.493 1.00 55.20  ? 618 TRP B C   1 
ATOM   11011 O  O   . TRP B 1 618 ? 206.363 242.267 167.390 1.00 55.20  ? 618 TRP B O   1 
ATOM   11012 C  CB  . TRP B 1 618 ? 206.456 243.069 170.571 1.00 55.20  ? 618 TRP B CB  1 
ATOM   11013 C  CG  . TRP B 1 618 ? 207.257 244.042 169.790 1.00 55.20  ? 618 TRP B CG  1 
ATOM   11014 C  CD1 . TRP B 1 618 ? 206.813 245.208 169.251 1.00 55.20  ? 618 TRP B CD1 1 
ATOM   11015 C  CD2 . TRP B 1 618 ? 208.631 243.925 169.423 1.00 55.20  ? 618 TRP B CD2 1 
ATOM   11016 N  NE1 . TRP B 1 618 ? 207.828 245.835 168.584 1.00 55.20  ? 618 TRP B NE1 1 
ATOM   11017 C  CE2 . TRP B 1 618 ? 208.958 245.068 168.675 1.00 55.20  ? 618 TRP B CE2 1 
ATOM   11018 C  CE3 . TRP B 1 618 ? 209.620 242.972 169.663 1.00 55.20  ? 618 TRP B CE3 1 
ATOM   11019 C  CZ2 . TRP B 1 618 ? 210.232 245.284 168.161 1.00 55.20  ? 618 TRP B CZ2 1 
ATOM   11020 C  CZ3 . TRP B 1 618 ? 210.886 243.186 169.153 1.00 55.20  ? 618 TRP B CZ3 1 
ATOM   11021 C  CH2 . TRP B 1 618 ? 211.180 244.333 168.410 1.00 55.20  ? 618 TRP B CH2 1 
ATOM   11022 N  N   . VAL B 1 619 ? 207.145 240.639 168.726 1.00 56.50  ? 619 VAL B N   1 
ATOM   11023 C  CA  . VAL B 1 619 ? 208.011 240.138 167.663 1.00 56.50  ? 619 VAL B CA  1 
ATOM   11024 C  C   . VAL B 1 619 ? 207.172 239.658 166.488 1.00 56.50  ? 619 VAL B C   1 
ATOM   11025 O  O   . VAL B 1 619 ? 207.470 239.968 165.329 1.00 56.50  ? 619 VAL B O   1 
ATOM   11026 C  CB  . VAL B 1 619 ? 208.967 239.046 168.182 1.00 56.50  ? 619 VAL B CB  1 
ATOM   11027 C  CG1 . VAL B 1 619 ? 208.222 237.842 168.681 1.00 56.50  ? 619 VAL B CG1 1 
ATOM   11028 C  CG2 . VAL B 1 619 ? 209.929 238.640 167.088 1.00 56.50  ? 619 VAL B CG2 1 
ATOM   11029 N  N   . ILE B 1 620 ? 206.078 238.945 166.767 1.00 57.88  ? 620 ILE B N   1 
ATOM   11030 C  CA  . ILE B 1 620 ? 205.248 238.427 165.682 1.00 57.88  ? 620 ILE B CA  1 
ATOM   11031 C  C   . ILE B 1 620 ? 204.641 239.573 164.882 1.00 57.88  ? 620 ILE B C   1 
ATOM   11032 O  O   . ILE B 1 620 ? 204.741 239.619 163.648 1.00 57.88  ? 620 ILE B O   1 
ATOM   11033 C  CB  . ILE B 1 620 ? 204.163 237.492 166.242 1.00 57.88  ? 620 ILE B CB  1 
ATOM   11034 C  CG1 . ILE B 1 620 ? 204.796 236.195 166.745 1.00 57.88  ? 620 ILE B CG1 1 
ATOM   11035 C  CG2 . ILE B 1 620 ? 203.115 237.203 165.184 1.00 57.88  ? 620 ILE B CG2 1 
ATOM   11036 C  CD1 . ILE B 1 620 ? 205.115 235.203 165.650 1.00 57.88  ? 620 ILE B CD1 1 
ATOM   11037 N  N   . ALA B 1 621 ? 204.018 240.529 165.576 1.00 60.98  ? 621 ALA B N   1 
ATOM   11038 C  CA  . ALA B 1 621 ? 203.349 241.621 164.880 1.00 60.98  ? 621 ALA B CA  1 
ATOM   11039 C  C   . ALA B 1 621 ? 204.342 242.468 164.095 1.00 60.98  ? 621 ALA B C   1 
ATOM   11040 O  O   . ALA B 1 621 ? 204.097 242.816 162.933 1.00 60.98  ? 621 ALA B O   1 
ATOM   11041 C  CB  . ALA B 1 621 ? 202.576 242.481 165.879 1.00 60.98  ? 621 ALA B CB  1 
ATOM   11042 N  N   . GLU B 1 622 ? 205.470 242.818 164.718 1.00 62.11  ? 622 GLU B N   1 
ATOM   11043 C  CA  . GLU B 1 622 ? 206.445 243.670 164.051 1.00 62.11  ? 622 GLU B CA  1 
ATOM   11044 C  C   . GLU B 1 622 ? 207.055 242.974 162.845 1.00 62.11  ? 622 GLU B C   1 
ATOM   11045 O  O   . GLU B 1 622 ? 207.258 243.600 161.800 1.00 62.11  ? 622 GLU B O   1 
ATOM   11046 C  CB  . GLU B 1 622 ? 207.530 244.097 165.038 1.00 62.11  ? 622 GLU B CB  1 
ATOM   11047 C  CG  . GLU B 1 622 ? 208.787 244.647 164.384 1.00 62.11  ? 622 GLU B CG  1 
ATOM   11048 C  CD  . GLU B 1 622 ? 208.766 246.153 164.240 1.00 62.11  ? 622 GLU B CD  1 
ATOM   11049 O  OE1 . GLU B 1 622 ? 207.722 246.766 164.544 1.00 62.11  ? 622 GLU B OE1 1 
ATOM   11050 O  OE2 . GLU B 1 622 ? 209.792 246.724 163.821 1.00 62.11  ? 622 GLU B OE2 1 
ATOM   11051 N  N   . ALA B 1 623 ? 207.364 241.680 162.965 1.00 61.73  ? 623 ALA B N   1 
ATOM   11052 C  CA  . ALA B 1 623 ? 207.911 240.963 161.822 1.00 61.73  ? 623 ALA B CA  1 
ATOM   11053 C  C   . ALA B 1 623 ? 206.908 240.913 160.683 1.00 61.73  ? 623 ALA B C   1 
ATOM   11054 O  O   . ALA B 1 623 ? 207.267 241.122 159.516 1.00 61.73  ? 623 ALA B O   1 
ATOM   11055 C  CB  . ALA B 1 623 ? 208.328 239.552 162.236 1.00 61.73  ? 623 ALA B CB  1 
ATOM   11056 N  N   . CYS B 1 624 ? 205.638 240.649 160.998 1.00 67.54  ? 624 CYS B N   1 
ATOM   11057 C  CA  . CYS B 1 624 ? 204.637 240.621 159.942 1.00 67.54  ? 624 CYS B CA  1 
ATOM   11058 C  C   . CYS B 1 624 ? 204.534 241.974 159.257 1.00 67.54  ? 624 CYS B C   1 
ATOM   11059 O  O   . CYS B 1 624 ? 204.528 242.052 158.025 1.00 67.54  ? 624 CYS B O   1 
ATOM   11060 C  CB  . CYS B 1 624 ? 203.283 240.198 160.507 1.00 67.54  ? 624 CYS B CB  1 
ATOM   11061 S  SG  . CYS B 1 624 ? 202.054 239.811 159.244 1.00 67.54  ? 624 CYS B SG  1 
ATOM   11062 N  N   . ARG B 1 625 ? 204.486 243.057 160.038 1.00 66.57  ? 625 ARG B N   1 
ATOM   11063 C  CA  . ARG B 1 625 ? 204.332 244.382 159.446 1.00 66.57  ? 625 ARG B CA  1 
ATOM   11064 C  C   . ARG B 1 625 ? 205.541 244.753 158.598 1.00 66.57  ? 625 ARG B C   1 
ATOM   11065 O  O   . ARG B 1 625 ? 205.399 245.294 157.495 1.00 66.57  ? 625 ARG B O   1 
ATOM   11066 C  CB  . ARG B 1 625 ? 204.104 245.422 160.537 1.00 66.57  ? 625 ARG B CB  1 
ATOM   11067 C  CG  . ARG B 1 625 ? 204.270 246.856 160.072 1.00 66.57  ? 625 ARG B CG  1 
ATOM   11068 C  CD  . ARG B 1 625 ? 204.675 247.745 161.229 1.00 66.57  ? 625 ARG B CD  1 
ATOM   11069 N  NE  . ARG B 1 625 ? 206.117 247.733 161.428 1.00 66.57  ? 625 ARG B NE  1 
ATOM   11070 C  CZ  . ARG B 1 625 ? 206.969 248.538 160.808 1.00 66.57  ? 625 ARG B CZ  1 
ATOM   11071 N  NH1 . ARG B 1 625 ? 206.552 249.473 159.969 1.00 66.57  ? 625 ARG B NH1 1 
ATOM   11072 N  NH2 . ARG B 1 625 ? 208.272 248.405 161.039 1.00 66.57  ? 625 ARG B NH2 1 
ATOM   11073 N  N   . GLN B 1 626 ? 206.741 244.467 159.101 1.00 66.62  ? 626 GLN B N   1 
ATOM   11074 C  CA  . GLN B 1 626 ? 207.961 244.789 158.379 1.00 66.62  ? 626 GLN B CA  1 
ATOM   11075 C  C   . GLN B 1 626 ? 208.099 243.989 157.095 1.00 66.62  ? 626 GLN B C   1 
ATOM   11076 O  O   . GLN B 1 626 ? 208.622 244.516 156.108 1.00 66.62  ? 626 GLN B O   1 
ATOM   11077 C  CB  . GLN B 1 626 ? 209.171 244.562 159.273 1.00 66.62  ? 626 GLN B CB  1 
ATOM   11078 C  CG  . GLN B 1 626 ? 210.448 245.125 158.712 1.00 66.62  ? 626 GLN B CG  1 
ATOM   11079 C  CD  . GLN B 1 626 ? 210.370 246.611 158.457 1.00 66.62  ? 626 GLN B CD  1 
ATOM   11080 O  OE1 . GLN B 1 626 ? 210.429 247.417 159.385 1.00 66.62  ? 626 GLN B OE1 1 
ATOM   11081 N  NE2 . GLN B 1 626 ? 210.237 246.986 157.191 1.00 66.62  ? 626 GLN B NE2 1 
ATOM   11082 N  N   . LEU B 1 627 ? 207.655 242.731 157.083 1.00 68.79  ? 627 LEU B N   1 
ATOM   11083 C  CA  . LEU B 1 627 ? 207.560 242.021 155.814 1.00 68.79  ? 627 LEU B CA  1 
ATOM   11084 C  C   . LEU B 1 627 ? 206.488 242.631 154.924 1.00 68.79  ? 627 LEU B C   1 
ATOM   11085 O  O   . LEU B 1 627 ? 206.618 242.609 153.694 1.00 68.79  ? 627 LEU B O   1 
ATOM   11086 C  CB  . LEU B 1 627 ? 207.275 240.537 156.055 1.00 68.79  ? 627 LEU B CB  1 
ATOM   11087 C  CG  . LEU B 1 627 ? 207.120 239.654 154.815 1.00 68.79  ? 627 LEU B CG  1 
ATOM   11088 C  CD1 . LEU B 1 627 ? 207.919 238.367 154.947 1.00 68.79  ? 627 LEU B CD1 1 
ATOM   11089 C  CD2 . LEU B 1 627 ? 205.653 239.341 154.572 1.00 68.79  ? 627 LEU B CD2 1 
ATOM   11090 N  N   . ALA B 1 628 ? 205.427 243.164 155.531 1.00 68.84  ? 628 ALA B N   1 
ATOM   11091 C  CA  . ALA B 1 628 ? 204.322 243.707 154.755 1.00 68.84  ? 628 ALA B CA  1 
ATOM   11092 C  C   . ALA B 1 628 ? 204.747 244.927 153.954 1.00 68.84  ? 628 ALA B C   1 
ATOM   11093 O  O   . ALA B 1 628 ? 204.373 245.061 152.783 1.00 68.84  ? 628 ALA B O   1 
ATOM   11094 C  CB  . ALA B 1 628 ? 203.150 244.047 155.674 1.00 68.84  ? 628 ALA B CB  1 
ATOM   11095 N  N   . GLU B 1 629 ? 205.517 245.836 154.559 1.00 69.56  ? 629 GLU B N   1 
ATOM   11096 C  CA  . GLU B 1 629 ? 205.938 247.000 153.777 1.00 69.56  ? 629 GLU B CA  1 
ATOM   11097 C  C   . GLU B 1 629 ? 206.735 246.575 152.551 1.00 69.56  ? 629 GLU B C   1 
ATOM   11098 O  O   . GLU B 1 629 ? 206.495 247.065 151.442 1.00 69.56  ? 629 GLU B O   1 
ATOM   11099 C  CB  . GLU B 1 629 ? 206.742 248.033 154.580 1.00 69.56  ? 629 GLU B CB  1 
ATOM   11100 C  CG  . GLU B 1 629 ? 205.969 248.898 155.575 1.00 69.56  ? 629 GLU B CG  1 
ATOM   11101 C  CD  . GLU B 1 629 ? 205.968 248.367 156.974 1.00 69.56  ? 629 GLU B CD  1 
ATOM   11102 O  OE1 . GLU B 1 629 ? 206.697 247.393 157.220 1.00 69.56  ? 629 GLU B OE1 1 
ATOM   11103 O  OE2 . GLU B 1 629 ? 205.254 248.934 157.828 1.00 69.56  ? 629 GLU B OE2 1 
ATOM   11104 N  N   . TRP B 1 630 ? 207.680 245.651 152.723 1.00 68.54  ? 630 TRP B N   1 
ATOM   11105 C  CA  . TRP B 1 630 ? 208.501 245.232 151.590 1.00 68.54  ? 630 TRP B CA  1 
ATOM   11106 C  C   . TRP B 1 630 ? 207.681 244.497 150.536 1.00 68.54  ? 630 TRP B C   1 
ATOM   11107 O  O   . TRP B 1 630 ? 207.854 244.734 149.335 1.00 68.54  ? 630 TRP B O   1 
ATOM   11108 C  CB  . TRP B 1 630 ? 209.653 244.353 152.064 1.00 68.54  ? 630 TRP B CB  1 
ATOM   11109 C  CG  . TRP B 1 630 ? 210.459 244.972 153.138 1.00 68.54  ? 630 TRP B CG  1 
ATOM   11110 C  CD1 . TRP B 1 630 ? 210.720 246.294 153.306 1.00 68.54  ? 630 TRP B CD1 1 
ATOM   11111 C  CD2 . TRP B 1 630 ? 211.128 244.289 154.198 1.00 68.54  ? 630 TRP B CD2 1 
ATOM   11112 N  NE1 . TRP B 1 630 ? 211.508 246.480 154.412 1.00 68.54  ? 630 TRP B NE1 1 
ATOM   11113 C  CE2 . TRP B 1 630 ? 211.770 245.260 154.977 1.00 68.54  ? 630 TRP B CE2 1 
ATOM   11114 C  CE3 . TRP B 1 630 ? 211.243 242.945 154.564 1.00 68.54  ? 630 TRP B CE3 1 
ATOM   11115 C  CZ2 . TRP B 1 630 ? 212.517 244.937 156.099 1.00 68.54  ? 630 TRP B CZ2 1 
ATOM   11116 C  CZ3 . TRP B 1 630 ? 211.981 242.625 155.678 1.00 68.54  ? 630 TRP B CZ3 1 
ATOM   11117 C  CH2 . TRP B 1 630 ? 212.610 243.615 156.435 1.00 68.54  ? 630 TRP B CH2 1 
ATOM   11118 N  N   . ARG B 1 631 ? 206.790 243.596 150.958 1.00 72.37  ? 631 ARG B N   1 
ATOM   11119 C  CA  . ARG B 1 631 ? 205.961 242.893 149.986 1.00 72.37  ? 631 ARG B CA  1 
ATOM   11120 C  C   . ARG B 1 631 ? 205.095 243.872 149.211 1.00 72.37  ? 631 ARG B C   1 
ATOM   11121 O  O   . ARG B 1 631 ? 204.883 243.704 148.004 1.00 72.37  ? 631 ARG B O   1 
ATOM   11122 C  CB  . ARG B 1 631 ? 205.092 241.845 150.680 1.00 72.37  ? 631 ARG B CB  1 
ATOM   11123 C  CG  . ARG B 1 631 ? 204.395 240.900 149.713 1.00 72.37  ? 631 ARG B CG  1 
ATOM   11124 C  CD  . ARG B 1 631 ? 203.199 240.220 150.353 1.00 72.37  ? 631 ARG B CD  1 
ATOM   11125 N  NE  . ARG B 1 631 ? 202.013 241.066 150.336 1.00 72.37  ? 631 ARG B NE  1 
ATOM   11126 C  CZ  . ARG B 1 631 ? 200.983 240.924 151.159 1.00 72.37  ? 631 ARG B CZ  1 
ATOM   11127 N  NH1 . ARG B 1 631 ? 200.955 239.967 152.071 1.00 72.37  ? 631 ARG B NH1 1 
ATOM   11128 N  NH2 . ARG B 1 631 ? 199.955 241.762 151.062 1.00 72.37  ? 631 ARG B NH2 1 
ATOM   11129 N  N   . SER B 1 632 ? 204.585 244.903 149.887 1.00 71.76  ? 632 SER B N   1 
ATOM   11130 C  CA  . SER B 1 632 ? 203.847 245.949 149.191 1.00 71.76  ? 632 SER B CA  1 
ATOM   11131 C  C   . SER B 1 632 ? 204.739 246.661 148.184 1.00 71.76  ? 632 SER B C   1 
ATOM   11132 O  O   . SER B 1 632 ? 204.324 246.935 147.053 1.00 71.76  ? 632 SER B O   1 
ATOM   11133 C  CB  . SER B 1 632 ? 203.270 246.940 150.200 1.00 71.76  ? 632 SER B CB  1 
ATOM   11134 O  OG  . SER B 1 632 ? 204.305 247.601 150.904 1.00 71.76  ? 632 SER B OG  1 
ATOM   11135 N  N   . GLN B 1 633 ? 205.973 246.962 148.577 1.00 71.00  ? 633 GLN B N   1 
ATOM   11136 C  CA  . GLN B 1 633 ? 206.909 247.553 147.637 1.00 71.00  ? 633 GLN B CA  1 
ATOM   11137 C  C   . GLN B 1 633 ? 207.299 246.526 146.577 1.00 71.00  ? 633 GLN B C   1 
ATOM   11138 O  O   . GLN B 1 633 ? 206.998 245.336 146.682 1.00 71.00  ? 633 GLN B O   1 
ATOM   11139 C  CB  . GLN B 1 633 ? 208.148 248.074 148.359 1.00 71.00  ? 633 GLN B CB  1 
ATOM   11140 C  CG  . GLN B 1 633 ? 207.852 249.079 149.453 1.00 71.00  ? 633 GLN B CG  1 
ATOM   11141 C  CD  . GLN B 1 633 ? 206.722 250.024 149.099 1.00 71.00  ? 633 GLN B CD  1 
ATOM   11142 O  OE1 . GLN B 1 633 ? 206.750 250.686 148.061 1.00 71.00  ? 633 GLN B OE1 1 
ATOM   11143 N  NE2 . GLN B 1 633 ? 205.719 250.093 149.964 1.00 71.00  ? 633 GLN B NE2 1 
ATOM   11144 N  N   . ASN B 1 634 ? 207.984 247.003 145.540 1.00 76.83  ? 634 ASN B N   1 
ATOM   11145 C  CA  . ASN B 1 634 ? 208.339 246.138 144.421 1.00 76.83  ? 634 ASN B CA  1 
ATOM   11146 C  C   . ASN B 1 634 ? 209.507 245.232 144.788 1.00 76.83  ? 634 ASN B C   1 
ATOM   11147 O  O   . ASN B 1 634 ? 210.554 245.258 144.132 1.00 76.83  ? 634 ASN B O   1 
ATOM   11148 C  CB  . ASN B 1 634 ? 208.677 246.971 143.183 1.00 76.83  ? 634 ASN B CB  1 
ATOM   11149 C  CG  . ASN B 1 634 ? 208.618 246.160 141.902 1.00 76.83  ? 634 ASN B CG  1 
ATOM   11150 O  OD1 . ASN B 1 634 ? 207.919 245.150 141.826 1.00 76.83  ? 634 ASN B OD1 1 
ATOM   11151 N  ND2 . ASN B 1 634 ? 209.354 246.600 140.888 1.00 76.83  ? 634 ASN B ND2 1 
ATOM   11152 N  N   . ILE B 1 635 ? 209.332 244.426 145.831 1.00 74.25  ? 635 ILE B N   1 
ATOM   11153 C  CA  . ILE B 1 635 ? 210.354 243.485 146.269 1.00 74.25  ? 635 ILE B CA  1 
ATOM   11154 C  C   . ILE B 1 635 ? 209.665 242.375 147.049 1.00 74.25  ? 635 ILE B C   1 
ATOM   11155 O  O   . ILE B 1 635 ? 208.660 242.603 147.728 1.00 74.25  ? 635 ILE B O   1 
ATOM   11156 C  CB  . ILE B 1 635 ? 211.453 244.192 147.101 1.00 74.25  ? 635 ILE B CB  1 
ATOM   11157 C  CG1 . ILE B 1 635 ? 212.745 243.374 147.086 1.00 74.25  ? 635 ILE B CG1 1 
ATOM   11158 C  CG2 . ILE B 1 635 ? 210.985 244.453 148.525 1.00 74.25  ? 635 ILE B CG2 1 
ATOM   11159 C  CD1 . ILE B 1 635 ? 213.425 243.329 145.735 1.00 74.25  ? 635 ILE B CD1 1 
ATOM   11160 N  N   . HIS B 1 636 ? 210.201 241.163 146.927 1.00 75.51  ? 636 HIS B N   1 
ATOM   11161 C  CA  . HIS B 1 636 ? 209.614 239.995 147.564 1.00 75.51  ? 636 HIS B CA  1 
ATOM   11162 C  C   . HIS B 1 636 ? 210.715 239.114 148.132 1.00 75.51  ? 636 HIS B C   1 
ATOM   11163 O  O   . HIS B 1 636 ? 211.774 238.941 147.524 1.00 75.51  ? 636 HIS B O   1 
ATOM   11164 C  CB  . HIS B 1 636 ? 208.752 239.194 146.578 1.00 75.51  ? 636 HIS B CB  1 
ATOM   11165 C  CG  . HIS B 1 636 ? 208.179 237.938 147.159 1.00 75.51  ? 636 HIS B CG  1 
ATOM   11166 N  ND1 . HIS B 1 636 ? 208.855 236.737 147.148 1.00 75.51  ? 636 HIS B ND1 1 
ATOM   11167 C  CD2 . HIS B 1 636 ? 206.994 237.697 147.767 1.00 75.51  ? 636 HIS B CD2 1 
ATOM   11168 C  CE1 . HIS B 1 636 ? 208.111 235.810 147.725 1.00 75.51  ? 636 HIS B CE1 1 
ATOM   11169 N  NE2 . HIS B 1 636 ? 206.976 236.367 148.109 1.00 75.51  ? 636 HIS B NE2 1 
ATOM   11170 N  N   . ILE B 1 637 ? 210.449 238.558 149.312 1.00 64.53  ? 637 ILE B N   1 
ATOM   11171 C  CA  . ILE B 1 637 ? 211.376 237.635 149.967 1.00 64.53  ? 637 ILE B CA  1 
ATOM   11172 C  C   . ILE B 1 637 ? 210.632 236.373 150.350 1.00 64.53  ? 637 ILE B C   1 
ATOM   11173 O  O   . ILE B 1 637 ? 209.429 236.394 150.640 1.00 64.53  ? 637 ILE B O   1 
ATOM   11174 C  CB  . ILE B 1 637 ? 212.018 238.264 151.218 1.00 64.53  ? 637 ILE B CB  1 
ATOM   11175 C  CG1 . ILE B 1 637 ? 210.930 238.805 152.147 1.00 64.53  ? 637 ILE B CG1 1 
ATOM   11176 C  CG2 . ILE B 1 637 ? 212.998 239.350 150.823 1.00 64.53  ? 637 ILE B CG2 1 
ATOM   11177 C  CD1 . ILE B 1 637 ? 211.442 239.297 153.472 1.00 64.53  ? 637 ILE B CD1 1 
ATOM   11178 N  N   . PRO B 1 638 ? 211.332 235.238 150.342 1.00 54.97  ? 638 PRO B N   1 
ATOM   11179 C  CA  . PRO B 1 638 ? 210.629 233.959 150.531 1.00 54.97  ? 638 PRO B CA  1 
ATOM   11180 C  C   . PRO B 1 638 ? 209.932 233.829 151.875 1.00 54.97  ? 638 PRO B C   1 
ATOM   11181 O  O   . PRO B 1 638 ? 208.720 233.578 151.915 1.00 54.97  ? 638 PRO B O   1 
ATOM   11182 C  CB  . PRO B 1 638 ? 211.749 232.923 150.355 1.00 54.97  ? 638 PRO B CB  1 
ATOM   11183 C  CG  . PRO B 1 638 ? 213.013 233.687 150.431 1.00 54.97  ? 638 PRO B CG  1 
ATOM   11184 C  CD  . PRO B 1 638 ? 212.729 235.042 149.940 1.00 54.97  ? 638 PRO B CD  1 
ATOM   11185 N  N   . ALA B 1 639 ? 210.654 233.993 152.980 1.00 56.04  ? 639 ALA B N   1 
ATOM   11186 C  CA  . ALA B 1 639 ? 210.025 233.829 154.282 1.00 56.04  ? 639 ALA B CA  1 
ATOM   11187 C  C   . ALA B 1 639 ? 210.923 234.411 155.363 1.00 56.04  ? 639 ALA B C   1 
ATOM   11188 O  O   . ALA B 1 639 ? 212.136 234.563 155.181 1.00 56.04  ? 639 ALA B O   1 
ATOM   11189 C  CB  . ALA B 1 639 ? 209.728 232.357 154.587 1.00 56.04  ? 639 ALA B CB  1 
ATOM   11190 N  N   . LEU B 1 640 ? 210.302 234.730 156.494 1.00 49.28  ? 640 LEU B N   1 
ATOM   11191 C  CA  . LEU B 1 640 ? 211.001 235.111 157.709 1.00 49.28  ? 640 LEU B CA  1 
ATOM   11192 C  C   . LEU B 1 640 ? 210.729 234.053 158.761 1.00 49.28  ? 640 LEU B C   1 
ATOM   11193 O  O   . LEU B 1 640 ? 209.594 233.589 158.903 1.00 49.28  ? 640 LEU B O   1 
ATOM   11194 C  CB  . LEU B 1 640 ? 210.563 236.489 158.207 1.00 49.28  ? 640 LEU B CB  1 
ATOM   11195 C  CG  . LEU B 1 640 ? 209.177 236.690 158.819 1.00 49.28  ? 640 LEU B CG  1 
ATOM   11196 C  CD1 . LEU B 1 640 ? 209.221 236.522 160.325 1.00 49.28  ? 640 LEU B CD1 1 
ATOM   11197 C  CD2 . LEU B 1 640 ? 208.646 238.057 158.464 1.00 49.28  ? 640 LEU B CD2 1 
ATOM   11198 N  N   . SER B 1 641 ? 211.768 233.660 159.477 1.00 47.48  ? 641 SER B N   1 
ATOM   11199 C  CA  . SER B 1 641 ? 211.647 232.704 160.565 1.00 47.48  ? 641 SER B CA  1 
ATOM   11200 C  C   . SER B 1 641 ? 211.696 233.467 161.880 1.00 47.48  ? 641 SER B C   1 
ATOM   11201 O  O   . SER B 1 641 ? 212.663 234.188 162.149 1.00 47.48  ? 641 SER B O   1 
ATOM   11202 C  CB  . SER B 1 641 ? 212.755 231.657 160.495 1.00 47.48  ? 641 SER B CB  1 
ATOM   11203 O  OG  . SER B 1 641 ? 212.672 230.922 159.289 1.00 47.48  ? 641 SER B OG  1 
ATOM   11204 N  N   . VAL B 1 642 ? 210.647 233.329 162.681 1.00 47.45  ? 642 VAL B N   1 
ATOM   11205 C  CA  . VAL B 1 642 ? 210.539 234.007 163.964 1.00 47.45  ? 642 VAL B CA  1 
ATOM   11206 C  C   . VAL B 1 642 ? 210.685 232.950 165.050 1.00 47.45  ? 642 VAL B C   1 
ATOM   11207 O  O   . VAL B 1 642 ? 209.879 232.017 165.143 1.00 47.45  ? 642 VAL B O   1 
ATOM   11208 C  CB  . VAL B 1 642 ? 209.228 234.797 164.083 1.00 47.45  ? 642 VAL B CB  1 
ATOM   11209 C  CG1 . VAL B 1 642 ? 208.032 233.922 163.782 1.00 47.45  ? 642 VAL B CG1 1 
ATOM   11210 C  CG2 . VAL B 1 642 ? 209.105 235.396 165.461 1.00 47.45  ? 642 VAL B CG2 1 
ATOM   11211 N  N   . ASN B 1 643 ? 211.730 233.082 165.865 1.00 52.30  ? 643 ASN B N   1 
ATOM   11212 C  CA  . ASN B 1 643 ? 212.170 232.018 166.765 1.00 52.30  ? 643 ASN B CA  1 
ATOM   11213 C  C   . ASN B 1 643 ? 211.340 232.027 168.046 1.00 52.30  ? 643 ASN B C   1 
ATOM   11214 O  O   . ASN B 1 643 ? 211.737 232.549 169.090 1.00 52.30  ? 643 ASN B O   1 
ATOM   11215 C  CB  . ASN B 1 643 ? 213.655 232.172 167.054 1.00 52.30  ? 643 ASN B CB  1 
ATOM   11216 C  CG  . ASN B 1 643 ? 214.019 233.574 167.490 1.00 52.30  ? 643 ASN B CG  1 
ATOM   11217 O  OD1 . ASN B 1 643 ? 213.153 234.434 167.644 1.00 52.30  ? 643 ASN B OD1 1 
ATOM   11218 N  ND2 . ASN B 1 643 ? 215.309 233.815 167.689 1.00 52.30  ? 643 ASN B ND2 1 
ATOM   11219 N  N   . LEU B 1 644 ? 210.163 231.406 167.966 1.00 57.64  ? 644 LEU B N   1 
ATOM   11220 C  CA  . LEU B 1 644 ? 209.237 231.413 169.093 1.00 57.64  ? 644 LEU B CA  1 
ATOM   11221 C  C   . LEU B 1 644 ? 209.789 230.626 170.276 1.00 57.64  ? 644 LEU B C   1 
ATOM   11222 O  O   . LEU B 1 644 ? 209.825 231.120 171.411 1.00 57.64  ? 644 LEU B O   1 
ATOM   11223 C  CB  . LEU B 1 644 ? 207.885 230.855 168.654 1.00 57.64  ? 644 LEU B CB  1 
ATOM   11224 C  CG  . LEU B 1 644 ? 207.087 231.737 167.692 1.00 57.64  ? 644 LEU B CG  1 
ATOM   11225 C  CD1 . LEU B 1 644 ? 205.605 231.425 167.789 1.00 57.64  ? 644 LEU B CD1 1 
ATOM   11226 C  CD2 . LEU B 1 644 ? 207.345 233.215 167.950 1.00 57.64  ? 644 LEU B CD2 1 
ATOM   11227 N  N   . SER B 1 645 ? 210.229 229.393 170.031 1.00 58.54  ? 645 SER B N   1 
ATOM   11228 C  CA  . SER B 1 645 ? 210.697 228.569 171.137 1.00 58.54  ? 645 SER B CA  1 
ATOM   11229 C  C   . SER B 1 645 ? 211.973 229.128 171.744 1.00 58.54  ? 645 SER B C   1 
ATOM   11230 O  O   . SER B 1 645 ? 212.216 228.956 172.942 1.00 58.54  ? 645 SER B O   1 
ATOM   11231 C  CB  . SER B 1 645 ? 210.905 227.132 170.672 1.00 58.54  ? 645 SER B CB  1 
ATOM   11232 O  OG  . SER B 1 645 ? 211.089 226.266 171.777 1.00 58.54  ? 645 SER B OG  1 
ATOM   11233 N  N   . ALA B 1 646 ? 212.800 229.793 170.938 1.00 55.39  ? 646 ALA B N   1 
ATOM   11234 C  CA  . ALA B 1 646 ? 213.942 230.513 171.480 1.00 55.39  ? 646 ALA B CA  1 
ATOM   11235 C  C   . ALA B 1 646 ? 213.515 231.724 172.290 1.00 55.39  ? 646 ALA B C   1 
ATOM   11236 O  O   . ALA B 1 646 ? 214.205 232.088 173.246 1.00 55.39  ? 646 ALA B O   1 
ATOM   11237 C  CB  . ALA B 1 646 ? 214.883 230.941 170.353 1.00 55.39  ? 646 ALA B CB  1 
ATOM   11238 N  N   . LEU B 1 647 ? 212.396 232.352 171.933 1.00 55.56  ? 647 LEU B N   1 
ATOM   11239 C  CA  . LEU B 1 647 ? 211.831 233.442 172.714 1.00 55.56  ? 647 LEU B CA  1 
ATOM   11240 C  C   . LEU B 1 647 ? 210.954 232.956 173.855 1.00 55.56  ? 647 LEU B C   1 
ATOM   11241 O  O   . LEU B 1 647 ? 210.286 233.777 174.494 1.00 55.56  ? 647 LEU B O   1 
ATOM   11242 C  CB  . LEU B 1 647 ? 211.027 234.378 171.812 1.00 55.56  ? 647 LEU B CB  1 
ATOM   11243 C  CG  . LEU B 1 647 ? 211.848 235.293 170.910 1.00 55.56  ? 647 LEU B CG  1 
ATOM   11244 C  CD1 . LEU B 1 647 ? 210.938 236.022 169.959 1.00 55.56  ? 647 LEU B CD1 1 
ATOM   11245 C  CD2 . LEU B 1 647 ? 212.651 236.275 171.739 1.00 55.56  ? 647 LEU B CD2 1 
ATOM   11246 N  N   . HIS B 1 648 ? 210.923 231.646 174.099 1.00 62.71  ? 648 HIS B N   1 
ATOM   11247 C  CA  . HIS B 1 648 ? 210.138 231.067 175.190 1.00 62.71  ? 648 HIS B CA  1 
ATOM   11248 C  C   . HIS B 1 648 ? 208.653 231.328 174.986 1.00 62.71  ? 648 HIS B C   1 
ATOM   11249 O  O   . HIS B 1 648 ? 207.926 231.651 175.927 1.00 62.71  ? 648 HIS B O   1 
ATOM   11250 C  CB  . HIS B 1 648 ? 210.588 231.594 176.552 1.00 62.71  ? 648 HIS B CB  1 
ATOM   11251 C  CG  . HIS B 1 648 ? 211.783 230.894 177.117 1.00 62.71  ? 648 HIS B CG  1 
ATOM   11252 N  ND1 . HIS B 1 648 ? 212.494 231.389 178.188 1.00 62.71  ? 648 HIS B ND1 1 
ATOM   11253 C  CD2 . HIS B 1 648 ? 212.386 229.734 176.768 1.00 62.71  ? 648 HIS B CD2 1 
ATOM   11254 C  CE1 . HIS B 1 648 ? 213.488 230.567 178.472 1.00 62.71  ? 648 HIS B CE1 1 
ATOM   11255 N  NE2 . HIS B 1 648 ? 213.445 229.554 177.625 1.00 62.71  ? 648 HIS B NE2 1 
ATOM   11256 N  N   . PHE B 1 649 ? 208.200 231.184 173.740 1.00 70.88  ? 649 PHE B N   1 
ATOM   11257 C  CA  . PHE B 1 649 ? 206.800 231.406 173.403 1.00 70.88  ? 649 PHE B CA  1 
ATOM   11258 C  C   . PHE B 1 649 ? 205.884 230.389 174.057 1.00 70.88  ? 649 PHE B C   1 
ATOM   11259 O  O   . PHE B 1 649 ? 204.666 230.592 174.075 1.00 70.88  ? 649 PHE B O   1 
ATOM   11260 C  CB  . PHE B 1 649 ? 206.633 231.345 171.890 1.00 70.88  ? 649 PHE B CB  1 
ATOM   11261 C  CG  . PHE B 1 649 ? 205.570 232.247 171.355 1.00 70.88  ? 649 PHE B CG  1 
ATOM   11262 C  CD1 . PHE B 1 649 ? 205.830 233.585 171.127 1.00 70.88  ? 649 PHE B CD1 1 
ATOM   11263 C  CD2 . PHE B 1 649 ? 204.317 231.749 171.049 1.00 70.88  ? 649 PHE B CD2 1 
ATOM   11264 C  CE1 . PHE B 1 649 ? 204.852 234.414 170.617 1.00 70.88  ? 649 PHE B CE1 1 
ATOM   11265 C  CE2 . PHE B 1 649 ? 203.337 232.572 170.538 1.00 70.88  ? 649 PHE B CE2 1 
ATOM   11266 C  CZ  . PHE B 1 649 ? 203.604 233.908 170.324 1.00 70.88  ? 649 PHE B CZ  1 
ATOM   11267 N  N   . ARG B 1 650 ? 206.444 229.308 174.593 1.00 84.73  ? 650 ARG B N   1 
ATOM   11268 C  CA  . ARG B 1 650 ? 205.651 228.197 175.100 1.00 84.73  ? 650 ARG B CA  1 
ATOM   11269 C  C   . ARG B 1 650 ? 204.607 228.673 176.096 1.00 84.73  ? 650 ARG B C   1 
ATOM   11270 O  O   . ARG B 1 650 ? 204.935 229.147 177.187 1.00 84.73  ? 650 ARG B O   1 
ATOM   11271 C  CB  . ARG B 1 650 ? 206.568 227.152 175.742 1.00 84.73  ? 650 ARG B CB  1 
ATOM   11272 C  CG  . ARG B 1 650 ? 207.644 227.721 176.656 1.00 84.73  ? 650 ARG B CG  1 
ATOM   11273 C  CD  . ARG B 1 650 ? 208.322 226.618 177.454 1.00 84.73  ? 650 ARG B CD  1 
ATOM   11274 N  NE  . ARG B 1 650 ? 207.377 225.880 178.284 1.00 84.73  ? 650 ARG B NE  1 
ATOM   11275 C  CZ  . ARG B 1 650 ? 206.904 226.310 179.446 1.00 84.73  ? 650 ARG B CZ  1 
ATOM   11276 N  NH1 . ARG B 1 650 ? 207.271 227.474 179.955 1.00 84.73  ? 650 ARG B NH1 1 
ATOM   11277 N  NH2 . ARG B 1 650 ? 206.040 225.551 180.115 1.00 84.73  ? 650 ARG B NH2 1 
ATOM   11278 N  N   . SER B 1 651 ? 203.347 228.544 175.699 1.00 85.73  ? 651 SER B N   1 
ATOM   11279 C  CA  . SER B 1 651 ? 202.197 228.880 176.523 1.00 85.73  ? 651 SER B CA  1 
ATOM   11280 C  C   . SER B 1 651 ? 200.963 228.340 175.821 1.00 85.73  ? 651 SER B C   1 
ATOM   11281 O  O   . SER B 1 651 ? 201.011 227.971 174.645 1.00 85.73  ? 651 SER B O   1 
ATOM   11282 C  CB  . SER B 1 651 ? 202.078 230.390 176.753 1.00 85.73  ? 651 SER B CB  1 
ATOM   11283 O  OG  . SER B 1 651 ? 201.165 230.675 177.798 1.00 85.73  ? 651 SER B OG  1 
ATOM   11284 N  N   . ASN B 1 652 ? 199.854 228.297 176.557 1.00 86.37  ? 652 ASN B N   1 
ATOM   11285 C  CA  . ASN B 1 652 ? 198.617 227.802 175.969 1.00 86.37  ? 652 ASN B CA  1 
ATOM   11286 C  C   . ASN B 1 652 ? 198.139 228.697 174.834 1.00 86.37  ? 652 ASN B C   1 
ATOM   11287 O  O   . ASN B 1 652 ? 197.543 228.209 173.868 1.00 86.37  ? 652 ASN B O   1 
ATOM   11288 C  CB  . ASN B 1 652 ? 197.535 227.683 177.043 1.00 86.37  ? 652 ASN B CB  1 
ATOM   11289 C  CG  . ASN B 1 652 ? 196.337 226.882 176.577 1.00 86.37  ? 652 ASN B CG  1 
ATOM   11290 O  OD1 . ASN B 1 652 ? 196.461 225.713 176.212 1.00 86.37  ? 652 ASN B OD1 1 
ATOM   11291 N  ND2 . ASN B 1 652 ? 195.166 227.508 176.586 1.00 86.37  ? 652 ASN B ND2 1 
ATOM   11292 N  N   . GLN B 1 653 ? 198.399 229.996 174.922 1.00 84.87  ? 653 GLN B N   1 
ATOM   11293 C  CA  . GLN B 1 653 ? 197.865 230.958 173.962 1.00 84.87  ? 653 GLN B CA  1 
ATOM   11294 C  C   . GLN B 1 653 ? 198.849 231.190 172.817 1.00 84.87  ? 653 GLN B C   1 
ATOM   11295 O  O   . GLN B 1 653 ? 199.201 232.317 172.469 1.00 84.87  ? 653 GLN B O   1 
ATOM   11296 C  CB  . GLN B 1 653 ? 197.506 232.261 174.673 1.00 84.87  ? 653 GLN B CB  1 
ATOM   11297 C  CG  . GLN B 1 653 ? 198.656 232.917 175.428 1.00 84.87  ? 653 GLN B CG  1 
ATOM   11298 C  CD  . GLN B 1 653 ? 198.830 232.362 176.829 1.00 84.87  ? 653 GLN B CD  1 
ATOM   11299 O  OE1 . GLN B 1 653 ? 198.312 231.293 177.155 1.00 84.87  ? 653 GLN B OE1 1 
ATOM   11300 N  NE2 . GLN B 1 653 ? 199.562 233.088 177.665 1.00 84.87  ? 653 GLN B NE2 1 
ATOM   11301 N  N   . LEU B 1 654 ? 199.280 230.090 172.211 1.00 80.12  ? 654 LEU B N   1 
ATOM   11302 C  CA  . LEU B 1 654 ? 200.177 230.169 171.064 1.00 80.12  ? 654 LEU B CA  1 
ATOM   11303 C  C   . LEU B 1 654 ? 199.448 230.551 169.775 1.00 80.12  ? 654 LEU B C   1 
ATOM   11304 O  O   . LEU B 1 654 ? 199.826 231.540 169.137 1.00 80.12  ? 654 LEU B O   1 
ATOM   11305 C  CB  . LEU B 1 654 ? 200.925 228.844 170.883 1.00 80.12  ? 654 LEU B CB  1 
ATOM   11306 C  CG  . LEU B 1 654 ? 202.101 228.820 169.900 1.00 80.12  ? 654 LEU B CG  1 
ATOM   11307 C  CD1 . LEU B 1 654 ? 203.170 227.859 170.385 1.00 80.12  ? 654 LEU B CD1 1 
ATOM   11308 C  CD2 . LEU B 1 654 ? 201.662 228.440 168.497 1.00 80.12  ? 654 LEU B CD2 1 
ATOM   11309 N  N   . PRO B 1 655 ? 198.401 229.818 169.350 1.00 79.69  ? 655 PRO B N   1 
ATOM   11310 C  CA  . PRO B 1 655 ? 197.921 229.989 167.973 1.00 79.69  ? 655 PRO B CA  1 
ATOM   11311 C  C   . PRO B 1 655 ? 197.120 231.257 167.730 1.00 79.69  ? 655 PRO B C   1 
ATOM   11312 O  O   . PRO B 1 655 ? 197.118 231.776 166.610 1.00 79.69  ? 655 PRO B O   1 
ATOM   11313 C  CB  . PRO B 1 655 ? 197.055 228.745 167.758 1.00 79.69  ? 655 PRO B CB  1 
ATOM   11314 C  CG  . PRO B 1 655 ? 196.503 228.466 169.097 1.00 79.69  ? 655 PRO B CG  1 
ATOM   11315 C  CD  . PRO B 1 655 ? 197.578 228.837 170.083 1.00 79.69  ? 655 PRO B CD  1 
ATOM   11316 N  N   . ASN B 1 656 ? 196.428 231.755 168.755 1.00 78.85  ? 656 ASN B N   1 
ATOM   11317 C  CA  . ASN B 1 656 ? 195.526 232.884 168.554 1.00 78.85  ? 656 ASN B CA  1 
ATOM   11318 C  C   . ASN B 1 656 ? 196.282 234.107 168.054 1.00 78.85  ? 656 ASN B C   1 
ATOM   11319 O  O   . ASN B 1 656 ? 195.882 234.746 167.073 1.00 78.85  ? 656 ASN B O   1 
ATOM   11320 C  CB  . ASN B 1 656 ? 194.784 233.199 169.856 1.00 78.85  ? 656 ASN B CB  1 
ATOM   11321 C  CG  . ASN B 1 656 ? 195.717 233.324 171.052 1.00 78.85  ? 656 ASN B CG  1 
ATOM   11322 O  OD1 . ASN B 1 656 ? 196.885 233.684 170.912 1.00 78.85  ? 656 ASN B OD1 1 
ATOM   11323 N  ND2 . ASN B 1 656 ? 195.200 233.021 172.237 1.00 78.85  ? 656 ASN B ND2 1 
ATOM   11324 N  N   . GLN B 1 657 ? 197.385 234.441 168.717 1.00 79.10  ? 657 GLN B N   1 
ATOM   11325 C  CA  . GLN B 1 657 ? 198.151 235.621 168.340 1.00 79.10  ? 657 GLN B CA  1 
ATOM   11326 C  C   . GLN B 1 657 ? 198.788 235.450 166.969 1.00 79.10  ? 657 GLN B C   1 
ATOM   11327 O  O   . GLN B 1 657 ? 198.752 236.366 166.139 1.00 79.10  ? 657 GLN B O   1 
ATOM   11328 C  CB  . GLN B 1 657 ? 199.202 235.909 169.411 1.00 79.10  ? 657 GLN B CB  1 
ATOM   11329 C  CG  . GLN B 1 657 ? 199.883 234.663 169.953 1.00 79.10  ? 657 GLN B CG  1 
ATOM   11330 C  CD  . GLN B 1 657 ? 200.496 234.894 171.321 1.00 79.10  ? 657 GLN B CD  1 
ATOM   11331 O  OE1 . GLN B 1 657 ? 200.575 236.026 171.793 1.00 79.10  ? 657 GLN B OE1 1 
ATOM   11332 N  NE2 . GLN B 1 657 ? 200.909 233.817 171.977 1.00 79.10  ? 657 GLN B NE2 1 
ATOM   11333 N  N   . VAL B 1 658 ? 199.369 234.278 166.707 1.00 78.04  ? 658 VAL B N   1 
ATOM   11334 C  CA  . VAL B 1 658 ? 199.993 234.053 165.408 1.00 78.04  ? 658 VAL B CA  1 
ATOM   11335 C  C   . VAL B 1 658 ? 198.972 234.197 164.295 1.00 78.04  ? 658 VAL B C   1 
ATOM   11336 O  O   . VAL B 1 658 ? 199.265 234.773 163.241 1.00 78.04  ? 658 VAL B O   1 
ATOM   11337 C  CB  . VAL B 1 658 ? 200.674 232.674 165.364 1.00 78.04  ? 658 VAL B CB  1 
ATOM   11338 C  CG1 . VAL B 1 658 ? 201.294 232.441 163.997 1.00 78.04  ? 658 VAL B CG1 1 
ATOM   11339 C  CG2 . VAL B 1 658 ? 201.724 232.568 166.458 1.00 78.04  ? 658 VAL B CG2 1 
ATOM   11340 N  N   . SER B 1 659 ? 197.758 233.692 164.509 1.00 82.01  ? 659 SER B N   1 
ATOM   11341 C  CA  . SER B 1 659 ? 196.734 233.791 163.478 1.00 82.01  ? 659 SER B CA  1 
ATOM   11342 C  C   . SER B 1 659 ? 196.266 235.229 163.292 1.00 82.01  ? 659 SER B C   1 
ATOM   11343 O  O   . SER B 1 659 ? 196.195 235.721 162.159 1.00 82.01  ? 659 SER B O   1 
ATOM   11344 C  CB  . SER B 1 659 ? 195.553 232.883 163.827 1.00 82.01  ? 659 SER B CB  1 
ATOM   11345 O  OG  . SER B 1 659 ? 194.989 233.241 165.076 1.00 82.01  ? 659 SER B OG  1 
ATOM   11346 N  N   . ASP B 1 660 ? 195.948 235.921 164.390 1.00 82.66  ? 660 ASP B N   1 
ATOM   11347 C  CA  . ASP B 1 660 ? 195.343 237.242 164.258 1.00 82.66  ? 660 ASP B CA  1 
ATOM   11348 C  C   . ASP B 1 660 ? 196.340 238.255 163.714 1.00 82.66  ? 660 ASP B C   1 
ATOM   11349 O  O   . ASP B 1 660 ? 195.976 239.126 162.912 1.00 82.66  ? 660 ASP B O   1 
ATOM   11350 C  CB  . ASP B 1 660 ? 194.750 237.695 165.598 1.00 82.66  ? 660 ASP B CB  1 
ATOM   11351 C  CG  . ASP B 1 660 ? 195.786 237.816 166.707 1.00 82.66  ? 660 ASP B CG  1 
ATOM   11352 O  OD1 . ASP B 1 660 ? 196.932 238.229 166.444 1.00 82.66  ? 660 ASP B OD1 1 
ATOM   11353 O  OD2 . ASP B 1 660 ? 195.441 237.493 167.864 1.00 82.66  ? 660 ASP B OD2 1 
ATOM   11354 N  N   . ALA B 1 661 ? 197.607 238.156 164.128 1.00 82.30  ? 661 ALA B N   1 
ATOM   11355 C  CA  . ALA B 1 661 ? 198.621 239.042 163.572 1.00 82.30  ? 661 ALA B CA  1 
ATOM   11356 C  C   . ALA B 1 661 ? 198.788 238.820 162.077 1.00 82.30  ? 661 ALA B C   1 
ATOM   11357 O  O   . ALA B 1 661 ? 198.944 239.784 161.319 1.00 82.30  ? 661 ALA B O   1 
ATOM   11358 C  CB  . ALA B 1 661 ? 199.952 238.843 164.296 1.00 82.30  ? 661 ALA B CB  1 
ATOM   11359 N  N   . MET B 1 662 ? 198.763 237.562 161.634 1.00 81.52  ? 662 MET B N   1 
ATOM   11360 C  CA  . MET B 1 662 ? 198.861 237.287 160.208 1.00 81.52  ? 662 MET B CA  1 
ATOM   11361 C  C   . MET B 1 662 ? 197.660 237.843 159.458 1.00 81.52  ? 662 MET B C   1 
ATOM   11362 O  O   . MET B 1 662 ? 197.810 238.418 158.374 1.00 81.52  ? 662 MET B O   1 
ATOM   11363 C  CB  . MET B 1 662 ? 198.991 235.783 159.973 1.00 81.52  ? 662 MET B CB  1 
ATOM   11364 C  CG  . MET B 1 662 ? 199.268 235.403 158.530 1.00 81.52  ? 662 MET B CG  1 
ATOM   11365 S  SD  . MET B 1 662 ? 197.770 235.037 157.598 1.00 81.52  ? 662 MET B SD  1 
ATOM   11366 C  CE  . MET B 1 662 ? 197.268 233.501 158.365 1.00 81.52  ? 662 MET B CE  1 
ATOM   11367 N  N   . HIS B 1 663 ? 196.466 237.683 160.028 1.00 80.31  ? 663 HIS B N   1 
ATOM   11368 C  CA  . HIS B 1 663 ? 195.260 238.177 159.373 1.00 80.31  ? 663 HIS B CA  1 
ATOM   11369 C  C   . HIS B 1 663 ? 195.270 239.695 159.273 1.00 80.31  ? 663 HIS B C   1 
ATOM   11370 O  O   . HIS B 1 663 ? 194.779 240.264 158.291 1.00 80.31  ? 663 HIS B O   1 
ATOM   11371 C  CB  . HIS B 1 663 ? 194.021 237.697 160.127 1.00 80.31  ? 663 HIS B CB  1 
ATOM   11372 C  CG  . HIS B 1 663 ? 192.731 238.166 159.531 1.00 80.31  ? 663 HIS B CG  1 
ATOM   11373 N  ND1 . HIS B 1 663 ? 192.130 237.532 158.465 1.00 80.31  ? 663 HIS B ND1 1 
ATOM   11374 C  CD2 . HIS B 1 663 ? 191.925 239.205 159.853 1.00 80.31  ? 663 HIS B CD2 1 
ATOM   11375 C  CE1 . HIS B 1 663 ? 191.011 238.161 158.155 1.00 80.31  ? 663 HIS B CE1 1 
ATOM   11376 N  NE2 . HIS B 1 663 ? 190.863 239.180 158.982 1.00 80.31  ? 663 HIS B NE2 1 
ATOM   11377 N  N   . ALA B 1 664 ? 195.827 240.368 160.281 1.00 76.87  ? 664 ALA B N   1 
ATOM   11378 C  CA  . ALA B 1 664 ? 195.821 241.825 160.288 1.00 76.87  ? 664 ALA B CA  1 
ATOM   11379 C  C   . ALA B 1 664 ? 196.578 242.409 159.102 1.00 76.87  ? 664 ALA B C   1 
ATOM   11380 O  O   . ALA B 1 664 ? 196.251 243.508 158.642 1.00 76.87  ? 664 ALA B O   1 
ATOM   11381 C  CB  . ALA B 1 664 ? 196.411 242.343 161.599 1.00 76.87  ? 664 ALA B CB  1 
ATOM   11382 N  N   . TRP B 1 665 ? 197.583 241.701 158.589 1.00 76.86  ? 665 TRP B N   1 
ATOM   11383 C  CA  . TRP B 1 665 ? 198.412 242.229 157.515 1.00 76.86  ? 665 TRP B CA  1 
ATOM   11384 C  C   . TRP B 1 665 ? 198.287 241.469 156.204 1.00 76.86  ? 665 TRP B C   1 
ATOM   11385 O  O   . TRP B 1 665 ? 198.834 241.926 155.194 1.00 76.86  ? 665 TRP B O   1 
ATOM   11386 C  CB  . TRP B 1 665 ? 199.886 242.258 157.940 1.00 76.86  ? 665 TRP B CB  1 
ATOM   11387 C  CG  . TRP B 1 665 ? 200.169 243.196 159.071 1.00 76.86  ? 665 TRP B CG  1 
ATOM   11388 C  CD1 . TRP B 1 665 ? 200.336 242.872 160.386 1.00 76.86  ? 665 TRP B CD1 1 
ATOM   11389 C  CD2 . TRP B 1 665 ? 200.320 244.618 158.986 1.00 76.86  ? 665 TRP B CD2 1 
ATOM   11390 N  NE1 . TRP B 1 665 ? 200.582 244.004 161.125 1.00 76.86  ? 665 TRP B NE1 1 
ATOM   11391 C  CE2 . TRP B 1 665 ? 200.576 245.089 160.289 1.00 76.86  ? 665 TRP B CE2 1 
ATOM   11392 C  CE3 . TRP B 1 665 ? 200.262 245.538 157.936 1.00 76.86  ? 665 TRP B CE3 1 
ATOM   11393 C  CZ2 . TRP B 1 665 ? 200.772 246.439 160.569 1.00 76.86  ? 665 TRP B CZ2 1 
ATOM   11394 C  CZ3 . TRP B 1 665 ? 200.458 246.878 158.215 1.00 76.86  ? 665 TRP B CZ3 1 
ATOM   11395 C  CH2 . TRP B 1 665 ? 200.711 247.315 159.520 1.00 76.86  ? 665 TRP B CH2 1 
ATOM   11396 N  N   . GLY B 1 666 ? 197.597 240.333 156.178 1.00 77.47  ? 666 GLY B N   1 
ATOM   11397 C  CA  . GLY B 1 666 ? 197.407 239.640 154.920 1.00 77.47  ? 666 GLY B CA  1 
ATOM   11398 C  C   . GLY B 1 666 ? 197.664 238.150 154.980 1.00 77.47  ? 666 GLY B C   1 
ATOM   11399 O  O   . GLY B 1 666 ? 198.444 237.677 155.811 1.00 77.47  ? 666 GLY B O   1 
ATOM   11400 N  N   . ILE B 1 667 ? 197.011 237.400 154.094 1.00 82.78  ? 667 ILE B N   1 
ATOM   11401 C  CA  . ILE B 1 667 ? 197.109 235.941 154.069 1.00 82.78  ? 667 ILE B CA  1 
ATOM   11402 C  C   . ILE B 1 667 ? 198.351 235.574 153.262 1.00 82.78  ? 667 ILE B C   1 
ATOM   11403 O  O   . ILE B 1 667 ? 198.303 235.459 152.037 1.00 82.78  ? 667 ILE B O   1 
ATOM   11404 C  CB  . ILE B 1 667 ? 195.848 235.294 153.493 1.00 82.78  ? 667 ILE B CB  1 
ATOM   11405 C  CG1 . ILE B 1 667 ? 194.599 235.859 154.175 1.00 82.78  ? 667 ILE B CG1 1 
ATOM   11406 C  CG2 . ILE B 1 667 ? 195.905 233.782 153.655 1.00 82.78  ? 667 ILE B CG2 1 
ATOM   11407 C  CD1 . ILE B 1 667 ? 194.592 235.690 155.680 1.00 82.78  ? 667 ILE B CD1 1 
ATOM   11408 N  N   . ASP B 1 668 ? 199.475 235.391 153.957 1.00 78.61  ? 668 ASP B N   1 
ATOM   11409 C  CA  . ASP B 1 668 ? 200.737 235.001 153.340 1.00 78.61  ? 668 ASP B CA  1 
ATOM   11410 C  C   . ASP B 1 668 ? 201.418 233.895 154.136 1.00 78.61  ? 668 ASP B C   1 
ATOM   11411 O  O   . ASP B 1 668 ? 202.614 233.986 154.431 1.00 78.61  ? 668 ASP B O   1 
ATOM   11412 C  CB  . ASP B 1 668 ? 201.667 236.207 153.199 1.00 78.61  ? 668 ASP B CB  1 
ATOM   11413 C  CG  . ASP B 1 668 ? 201.696 237.068 154.445 1.00 78.61  ? 668 ASP B CG  1 
ATOM   11414 O  OD1 . ASP B 1 668 ? 200.917 236.792 155.376 1.00 78.61  ? 668 ASP B OD1 1 
ATOM   11415 O  OD2 . ASP B 1 668 ? 202.499 238.020 154.493 1.00 78.61  ? 668 ASP B OD2 1 
ATOM   11416 N  N   . GLY B 1 669 ? 200.669 232.847 154.487 1.00 78.22  ? 669 GLY B N   1 
ATOM   11417 C  CA  . GLY B 1 669 ? 201.160 231.865 155.441 1.00 78.22  ? 669 GLY B CA  1 
ATOM   11418 C  C   . GLY B 1 669 ? 202.436 231.169 155.015 1.00 78.22  ? 669 GLY B C   1 
ATOM   11419 O  O   . GLY B 1 669 ? 203.232 230.754 155.861 1.00 78.22  ? 669 GLY B O   1 
ATOM   11420 N  N   . HIS B 1 670 ? 202.659 231.039 153.709 1.00 77.68  ? 670 HIS B N   1 
ATOM   11421 C  CA  . HIS B 1 670 ? 203.857 230.374 153.213 1.00 77.68  ? 670 HIS B CA  1 
ATOM   11422 C  C   . HIS B 1 670 ? 205.126 231.183 153.440 1.00 77.68  ? 670 HIS B C   1 
ATOM   11423 O  O   . HIS B 1 670 ? 206.219 230.656 153.212 1.00 77.68  ? 670 HIS B O   1 
ATOM   11424 C  CB  . HIS B 1 670 ? 203.702 230.074 151.723 1.00 77.68  ? 670 HIS B CB  1 
ATOM   11425 C  CG  . HIS B 1 670 ? 203.716 231.296 150.861 1.00 77.68  ? 670 HIS B CG  1 
ATOM   11426 N  ND1 . HIS B 1 670 ? 204.672 231.514 149.892 1.00 77.68  ? 670 HIS B ND1 1 
ATOM   11427 C  CD2 . HIS B 1 670 ? 202.895 232.372 150.828 1.00 77.68  ? 670 HIS B CD2 1 
ATOM   11428 C  CE1 . HIS B 1 670 ? 204.435 232.669 149.295 1.00 77.68  ? 670 HIS B CE1 1 
ATOM   11429 N  NE2 . HIS B 1 670 ? 203.363 233.209 149.844 1.00 77.68  ? 670 HIS B NE2 1 
ATOM   11430 N  N   . GLN B 1 671 ? 205.016 232.438 153.871 1.00 67.86  ? 671 GLN B N   1 
ATOM   11431 C  CA  . GLN B 1 671 ? 206.167 233.303 154.078 1.00 67.86  ? 671 GLN B CA  1 
ATOM   11432 C  C   . GLN B 1 671 ? 206.553 233.445 155.545 1.00 67.86  ? 671 GLN B C   1 
ATOM   11433 O  O   . GLN B 1 671 ? 207.333 234.338 155.882 1.00 67.86  ? 671 GLN B O   1 
ATOM   11434 C  CB  . GLN B 1 671 ? 205.897 234.691 153.492 1.00 67.86  ? 671 GLN B CB  1 
ATOM   11435 C  CG  . GLN B 1 671 ? 205.626 234.721 152.001 1.00 67.86  ? 671 GLN B CG  1 
ATOM   11436 C  CD  . GLN B 1 671 ? 205.644 236.133 151.434 1.00 67.86  ? 671 GLN B CD  1 
ATOM   11437 O  OE1 . GLN B 1 671 ? 206.440 236.975 151.851 1.00 67.86  ? 671 GLN B OE1 1 
ATOM   11438 N  NE2 . GLN B 1 671 ? 204.760 236.397 150.480 1.00 67.86  ? 671 GLN B NE2 1 
ATOM   11439 N  N   . LEU B 1 672 ? 206.020 232.609 156.427 1.00 56.98  ? 672 LEU B N   1 
ATOM   11440 C  CA  . LEU B 1 672 ? 206.290 232.723 157.851 1.00 56.98  ? 672 LEU B CA  1 
ATOM   11441 C  C   . LEU B 1 672 ? 206.569 231.344 158.429 1.00 56.98  ? 672 LEU B C   1 
ATOM   11442 O  O   . LEU B 1 672 ? 205.867 230.379 158.118 1.00 56.98  ? 672 LEU B O   1 
ATOM   11443 C  CB  . LEU B 1 672 ? 205.115 233.382 158.569 1.00 56.98  ? 672 LEU B CB  1 
ATOM   11444 C  CG  . LEU B 1 672 ? 205.365 233.928 159.970 1.00 56.98  ? 672 LEU B CG  1 
ATOM   11445 C  CD1 . LEU B 1 672 ? 204.524 235.166 160.199 1.00 56.98  ? 672 LEU B CD1 1 
ATOM   11446 C  CD2 . LEU B 1 672 ? 205.060 232.878 161.022 1.00 56.98  ? 672 LEU B CD2 1 
ATOM   11447 N  N   . THR B 1 673 ? 207.597 231.256 159.271 1.00 51.46  ? 673 THR B N   1 
ATOM   11448 C  CA  . THR B 1 673 ? 208.070 229.986 159.803 1.00 51.46  ? 673 THR B CA  1 
ATOM   11449 C  C   . THR B 1 673 ? 208.355 230.136 161.292 1.00 51.46  ? 673 THR B C   1 
ATOM   11450 O  O   . THR B 1 673 ? 208.848 231.168 161.751 1.00 51.46  ? 673 THR B O   1 
ATOM   11451 C  CB  . THR B 1 673 ? 209.325 229.502 159.057 1.00 51.46  ? 673 THR B CB  1 
ATOM   11452 O  OG1 . THR B 1 673 ? 208.967 229.083 157.737 1.00 51.46  ? 673 THR B OG1 1 
ATOM   11453 C  CG2 . THR B 1 673 ? 209.985 228.343 159.776 1.00 51.46  ? 673 THR B CG2 1 
ATOM   11454 N  N   . VAL B 1 674 ? 208.037 229.083 162.044 1.00 48.32  ? 674 VAL B N   1 
ATOM   11455 C  CA  . VAL B 1 674 ? 208.159 229.071 163.492 1.00 48.32  ? 674 VAL B CA  1 
ATOM   11456 C  C   . VAL B 1 674 ? 209.126 227.967 163.899 1.00 48.32  ? 674 VAL B C   1 
ATOM   11457 O  O   . VAL B 1 674 ? 209.138 226.876 163.325 1.00 48.32  ? 674 VAL B O   1 
ATOM   11458 C  CB  . VAL B 1 674 ? 206.786 228.876 164.166 1.00 48.32  ? 674 VAL B CB  1 
ATOM   11459 C  CG1 . VAL B 1 674 ? 206.930 228.733 165.671 1.00 48.32  ? 674 VAL B CG1 1 
ATOM   11460 C  CG2 . VAL B 1 674 ? 205.866 230.032 163.820 1.00 48.32  ? 674 VAL B CG2 1 
ATOM   11461 N  N   . GLU B 1 675 ? 209.949 228.269 164.901 1.00 52.55  ? 675 GLU B N   1 
ATOM   11462 C  CA  . GLU B 1 675 ? 210.978 227.365 165.394 1.00 52.55  ? 675 GLU B CA  1 
ATOM   11463 C  C   . GLU B 1 675 ? 210.513 226.684 166.674 1.00 52.55  ? 675 GLU B C   1 
ATOM   11464 O  O   . GLU B 1 675 ? 209.781 227.275 167.473 1.00 52.55  ? 675 GLU B O   1 
ATOM   11465 C  CB  . GLU B 1 675 ? 212.283 228.115 165.665 1.00 52.55  ? 675 GLU B CB  1 
ATOM   11466 C  CG  . GLU B 1 675 ? 212.849 228.845 164.462 1.00 52.55  ? 675 GLU B CG  1 
ATOM   11467 C  CD  . GLU B 1 675 ? 214.207 229.458 164.734 1.00 52.55  ? 675 GLU B CD  1 
ATOM   11468 O  OE1 . GLU B 1 675 ? 214.676 229.379 165.889 1.00 52.55  ? 675 GLU B OE1 1 
ATOM   11469 O  OE2 . GLU B 1 675 ? 214.807 230.018 163.792 1.00 52.55  ? 675 GLU B OE2 1 
ATOM   11470 N  N   . ILE B 1 676 ? 210.942 225.440 166.868 1.00 54.95  ? 676 ILE B N   1 
ATOM   11471 C  CA  . ILE B 1 676 ? 210.644 224.673 168.073 1.00 54.95  ? 676 ILE B CA  1 
ATOM   11472 C  C   . ILE B 1 676 ? 211.943 224.071 168.587 1.00 54.95  ? 676 ILE B C   1 
ATOM   11473 O  O   . ILE B 1 676 ? 212.706 223.485 167.810 1.00 54.95  ? 676 ILE B O   1 
ATOM   11474 C  CB  . ILE B 1 676 ? 209.608 223.570 167.816 1.00 54.95  ? 676 ILE B CB  1 
ATOM   11475 C  CG1 . ILE B 1 676 ? 208.247 224.180 167.501 1.00 54.95  ? 676 ILE B CG1 1 
ATOM   11476 C  CG2 . ILE B 1 676 ? 209.521 222.627 168.997 1.00 54.95  ? 676 ILE B CG2 1 
ATOM   11477 C  CD1 . ILE B 1 676 ? 208.026 224.430 166.045 1.00 54.95  ? 676 ILE B CD1 1 
ATOM   11478 N  N   . THR B 1 677 ? 212.195 224.208 169.888 1.00 64.95  ? 677 THR B N   1 
ATOM   11479 C  CA  . THR B 1 677 ? 213.461 223.755 170.452 1.00 64.95  ? 677 THR B CA  1 
ATOM   11480 C  C   . THR B 1 677 ? 213.438 222.280 170.818 1.00 64.95  ? 677 THR B C   1 
ATOM   11481 O  O   . THR B 1 677 ? 212.502 221.553 170.476 1.00 64.95  ? 677 THR B O   1 
ATOM   11482 C  CB  . THR B 1 677 ? 213.845 224.575 171.687 1.00 64.95  ? 677 THR B CB  1 
ATOM   11483 O  OG1 . THR B 1 677 ? 212.758 224.589 172.619 1.00 64.95  ? 677 THR B OG1 1 
ATOM   11484 C  CG2 . THR B 1 677 ? 214.223 225.998 171.302 1.00 64.95  ? 677 THR B CG2 1 
ATOM   11485 N  N   . GLU B 1 678 ? 214.477 221.844 171.530 1.00 79.38  ? 678 GLU B N   1 
ATOM   11486 C  CA  . GLU B 1 678 ? 214.682 220.440 171.859 1.00 79.38  ? 678 GLU B CA  1 
ATOM   11487 C  C   . GLU B 1 678 ? 213.618 219.919 172.815 1.00 79.38  ? 678 GLU B C   1 
ATOM   11488 O  O   . GLU B 1 678 ? 213.621 220.257 174.003 1.00 79.38  ? 678 GLU B O   1 
ATOM   11489 C  CB  . GLU B 1 678 ? 216.071 220.239 172.470 1.00 79.38  ? 678 GLU B CB  1 
ATOM   11490 C  CG  . GLU B 1 678 ? 216.363 218.808 172.891 1.00 79.38  ? 678 GLU B CG  1 
ATOM   11491 C  CD  . GLU B 1 678 ? 217.717 218.663 173.557 1.00 79.38  ? 678 GLU B CD  1 
ATOM   11492 O  OE1 . GLU B 1 678 ? 218.421 219.684 173.705 1.00 79.38  ? 678 GLU B OE1 1 
ATOM   11493 O  OE2 . GLU B 1 678 ? 218.077 217.528 173.935 1.00 79.38  ? 678 GLU B OE2 1 
ATOM   11494 N  N   . SER B 1 679 ? 212.707 219.101 172.295 1.00 80.79  ? 679 SER B N   1 
ATOM   11495 C  CA  . SER B 1 679 ? 211.752 218.368 173.114 1.00 80.79  ? 679 SER B CA  1 
ATOM   11496 C  C   . SER B 1 679 ? 210.898 219.283 173.981 1.00 80.79  ? 679 SER B C   1 
ATOM   11497 O  O   . SER B 1 679 ? 210.513 218.906 175.092 1.00 80.79  ? 679 SER B O   1 
ATOM   11498 C  CB  . SER B 1 679 ? 212.485 217.353 173.992 1.00 80.79  ? 679 SER B CB  1 
ATOM   11499 O  OG  . SER B 1 679 ? 213.166 216.395 173.200 1.00 80.79  ? 679 SER B OG  1 
ATOM   11500 N  N   . MET B 1 680 ? 210.598 220.483 173.497 1.00 81.61  ? 680 MET B N   1 
ATOM   11501 C  CA  . MET B 1 680 ? 209.616 221.335 174.148 1.00 81.61  ? 680 MET B CA  1 
ATOM   11502 C  C   . MET B 1 680 ? 208.207 221.053 173.660 1.00 81.61  ? 680 MET B C   1 
ATOM   11503 O  O   . MET B 1 680 ? 207.250 221.605 174.208 1.00 81.61  ? 680 MET B O   1 
ATOM   11504 C  CB  . MET B 1 680 ? 209.951 222.813 173.925 1.00 81.61  ? 680 MET B CB  1 
ATOM   11505 C  CG  . MET B 1 680 ? 209.808 223.280 172.487 1.00 81.61  ? 680 MET B CG  1 
ATOM   11506 S  SD  . MET B 1 680 ? 208.166 223.914 172.085 1.00 81.61  ? 680 MET B SD  1 
ATOM   11507 C  CE  . MET B 1 680 ? 208.190 225.491 172.931 1.00 81.61  ? 680 MET B CE  1 
ATOM   11508 N  N   . MET B 1 681 ? 208.061 220.212 172.643 1.00 84.43  ? 681 MET B N   1 
ATOM   11509 C  CA  . MET B 1 681 ? 206.769 219.872 172.074 1.00 84.43  ? 681 MET B CA  1 
ATOM   11510 C  C   . MET B 1 681 ? 206.236 218.538 172.577 1.00 84.43  ? 681 MET B C   1 
ATOM   11511 O  O   . MET B 1 681 ? 205.083 218.201 172.293 1.00 84.43  ? 681 MET B O   1 
ATOM   11512 C  CB  . MET B 1 681 ? 206.868 219.847 170.550 1.00 84.43  ? 681 MET B CB  1 
ATOM   11513 C  CG  . MET B 1 681 ? 207.846 218.821 170.023 1.00 84.43  ? 681 MET B CG  1 
ATOM   11514 S  SD  . MET B 1 681 ? 208.085 218.932 168.245 1.00 84.43  ? 681 MET B SD  1 
ATOM   11515 C  CE  . MET B 1 681 ? 206.504 218.342 167.658 1.00 84.43  ? 681 MET B CE  1 
ATOM   11516 N  N   . MET B 1 682 ? 207.042 217.774 173.311 1.00 92.36  ? 682 MET B N   1 
ATOM   11517 C  CA  . MET B 1 682 ? 206.638 216.434 173.714 1.00 92.36  ? 682 MET B CA  1 
ATOM   11518 C  C   . MET B 1 682 ? 206.548 216.298 175.227 1.00 92.36  ? 682 MET B C   1 
ATOM   11519 O  O   . MET B 1 682 ? 205.523 215.855 175.754 1.00 92.36  ? 682 MET B O   1 
ATOM   11520 C  CB  . MET B 1 682 ? 207.613 215.398 173.150 1.00 92.36  ? 682 MET B CB  1 
ATOM   11521 C  CG  . MET B 1 682 ? 206.972 214.061 172.820 1.00 92.36  ? 682 MET B CG  1 
ATOM   11522 S  SD  . MET B 1 682 ? 208.043 213.018 171.816 1.00 92.36  ? 682 MET B SD  1 
ATOM   11523 C  CE  . MET B 1 682 ? 208.548 214.184 170.555 1.00 92.36  ? 682 MET B CE  1 
ATOM   11524 N  N   . GLU B 1 683 ? 207.619 216.664 175.931 1.00 99.01  ? 683 GLU B N   1 
ATOM   11525 C  CA  . GLU B 1 683 ? 207.661 216.537 177.383 1.00 99.01  ? 683 GLU B CA  1 
ATOM   11526 C  C   . GLU B 1 683 ? 206.582 217.400 178.023 1.00 99.01  ? 683 GLU B C   1 
ATOM   11527 O  O   . GLU B 1 683 ? 205.907 216.970 178.964 1.00 99.01  ? 683 GLU B O   1 
ATOM   11528 C  CB  . GLU B 1 683 ? 209.042 216.922 177.917 1.00 99.01  ? 683 GLU B CB  1 
ATOM   11529 C  CG  . GLU B 1 683 ? 209.140 216.940 179.435 1.00 99.01  ? 683 GLU B CG  1 
ATOM   11530 C  CD  . GLU B 1 683 ? 209.030 218.339 180.011 1.00 99.01  ? 683 GLU B CD  1 
ATOM   11531 O  OE1 . GLU B 1 683 ? 209.250 219.312 179.260 1.00 99.01  ? 683 GLU B OE1 1 
ATOM   11532 O  OE2 . GLU B 1 683 ? 208.719 218.464 181.215 1.00 99.01  ? 683 GLU B OE2 1 
ATOM   11533 N  N   . HIS B 1 684 ? 206.412 218.614 177.515 1.00 97.55  ? 684 HIS B N   1 
ATOM   11534 C  CA  . HIS B 1 684 ? 205.374 219.524 177.967 1.00 97.55  ? 684 HIS B CA  1 
ATOM   11535 C  C   . HIS B 1 684 ? 204.679 220.109 176.744 1.00 97.55  ? 684 HIS B C   1 
ATOM   11536 O  O   . HIS B 1 684 ? 205.030 219.807 175.600 1.00 97.55  ? 684 HIS B O   1 
ATOM   11537 C  CB  . HIS B 1 684 ? 205.964 220.627 178.861 1.00 97.55  ? 684 HIS B CB  1 
ATOM   11538 C  CG  . HIS B 1 684 ? 204.936 221.465 179.556 1.00 97.55  ? 684 HIS B CG  1 
ATOM   11539 N  ND1 . HIS B 1 684 ? 204.662 222.765 179.189 1.00 97.55  ? 684 HIS B ND1 1 
ATOM   11540 C  CD2 . HIS B 1 684 ? 204.114 221.186 180.595 1.00 97.55  ? 684 HIS B CD2 1 
ATOM   11541 C  CE1 . HIS B 1 684 ? 203.716 223.251 179.973 1.00 97.55  ? 684 HIS B CE1 1 
ATOM   11542 N  NE2 . HIS B 1 684 ? 203.366 222.313 180.835 1.00 97.55  ? 684 HIS B NE2 1 
ATOM   11543 N  N   . ASP B 1 685 ? 203.673 220.949 176.994 1.00 95.19  ? 685 ASP B N   1 
ATOM   11544 C  CA  . ASP B 1 685 ? 202.878 221.609 175.965 1.00 95.19  ? 685 ASP B CA  1 
ATOM   11545 C  C   . ASP B 1 685 ? 202.179 220.622 175.041 1.00 95.19  ? 685 ASP B C   1 
ATOM   11546 O  O   . ASP B 1 685 ? 202.160 220.826 173.824 1.00 95.19  ? 685 ASP B O   1 
ATOM   11547 C  CB  . ASP B 1 685 ? 203.728 222.575 175.130 1.00 95.19  ? 685 ASP B CB  1 
ATOM   11548 C  CG  . ASP B 1 685 ? 204.440 223.608 175.979 1.00 95.19  ? 685 ASP B CG  1 
ATOM   11549 O  OD1 . ASP B 1 685 ? 203.867 224.035 177.002 1.00 95.19  ? 685 ASP B OD1 1 
ATOM   11550 O  OD2 . ASP B 1 685 ? 205.574 223.992 175.623 1.00 95.19  ? 685 ASP B OD2 1 
ATOM   11551 N  N   . THR B 1 686 ? 201.612 219.544 175.586 1.00 90.46  ? 686 THR B N   1 
ATOM   11552 C  CA  . THR B 1 686 ? 200.886 218.595 174.752 1.00 90.46  ? 686 THR B CA  1 
ATOM   11553 C  C   . THR B 1 686 ? 199.667 219.239 174.110 1.00 90.46  ? 686 THR B C   1 
ATOM   11554 O  O   . THR B 1 686 ? 199.356 218.963 172.946 1.00 90.46  ? 686 THR B O   1 
ATOM   11555 C  CB  . THR B 1 686 ? 200.471 217.379 175.579 1.00 90.46  ? 686 THR B CB  1 
ATOM   11556 O  OG1 . THR B 1 686 ? 199.798 217.814 176.766 1.00 90.46  ? 686 THR B OG1 1 
ATOM   11557 C  CG2 . THR B 1 686 ? 201.692 216.559 175.963 1.00 90.46  ? 686 THR B CG2 1 
ATOM   11558 N  N   . GLU B 1 687 ? 198.968 220.101 174.848 1.00 92.78  ? 687 GLU B N   1 
ATOM   11559 C  CA  . GLU B 1 687 ? 197.825 220.809 174.286 1.00 92.78  ? 687 GLU B CA  1 
ATOM   11560 C  C   . GLU B 1 687 ? 198.233 221.802 173.205 1.00 92.78  ? 687 GLU B C   1 
ATOM   11561 O  O   . GLU B 1 687 ? 197.386 222.207 172.402 1.00 92.78  ? 687 GLU B O   1 
ATOM   11562 C  CB  . GLU B 1 687 ? 197.053 221.522 175.397 1.00 92.78  ? 687 GLU B CB  1 
ATOM   11563 C  CG  . GLU B 1 687 ? 197.892 222.482 176.222 1.00 92.78  ? 687 GLU B CG  1 
ATOM   11564 C  CD  . GLU B 1 687 ? 197.260 222.808 177.561 1.00 92.78  ? 687 GLU B CD  1 
ATOM   11565 O  OE1 . GLU B 1 687 ? 196.145 222.312 177.831 1.00 92.78  ? 687 GLU B OE1 1 
ATOM   11566 O  OE2 . GLU B 1 687 ? 197.878 223.559 178.345 1.00 92.78  ? 687 GLU B OE2 1 
ATOM   11567 N  N   . ILE B 1 688 ? 199.503 222.206 173.169 1.00 90.74  ? 688 ILE B N   1 
ATOM   11568 C  CA  . ILE B 1 688 ? 199.977 223.065 172.089 1.00 90.74  ? 688 ILE B CA  1 
ATOM   11569 C  C   . ILE B 1 688 ? 200.428 222.227 170.901 1.00 90.74  ? 688 ILE B C   1 
ATOM   11570 O  O   . ILE B 1 688 ? 200.224 222.605 169.739 1.00 90.74  ? 688 ILE B O   1 
ATOM   11571 C  CB  . ILE B 1 688 ? 201.098 223.995 172.595 1.00 90.74  ? 688 ILE B CB  1 
ATOM   11572 C  CG1 . ILE B 1 688 ? 200.568 224.975 173.648 1.00 90.74  ? 688 ILE B CG1 1 
ATOM   11573 C  CG2 . ILE B 1 688 ? 201.733 224.753 171.444 1.00 90.74  ? 688 ILE B CG2 1 
ATOM   11574 C  CD1 . ILE B 1 688 ? 200.657 224.485 175.077 1.00 90.74  ? 688 ILE B CD1 1 
ATOM   11575 N  N   . PHE B 1 689 ? 201.064 221.088 171.171 1.00 89.47  ? 689 PHE B N   1 
ATOM   11576 C  CA  . PHE B 1 689 ? 201.429 220.174 170.097 1.00 89.47  ? 689 PHE B CA  1 
ATOM   11577 C  C   . PHE B 1 689 ? 200.187 219.646 169.394 1.00 89.47  ? 689 PHE B C   1 
ATOM   11578 O  O   . PHE B 1 689 ? 200.225 219.312 168.206 1.00 89.47  ? 689 PHE B O   1 
ATOM   11579 C  CB  . PHE B 1 689 ? 202.271 219.026 170.650 1.00 89.47  ? 689 PHE B CB  1 
ATOM   11580 C  CG  . PHE B 1 689 ? 202.330 217.830 169.746 1.00 89.47  ? 689 PHE B CG  1 
ATOM   11581 C  CD1 . PHE B 1 689 ? 202.930 217.914 168.502 1.00 89.47  ? 689 PHE B CD1 1 
ATOM   11582 C  CD2 . PHE B 1 689 ? 201.787 216.620 170.141 1.00 89.47  ? 689 PHE B CD2 1 
ATOM   11583 C  CE1 . PHE B 1 689 ? 202.981 216.817 167.667 1.00 89.47  ? 689 PHE B CE1 1 
ATOM   11584 C  CE2 . PHE B 1 689 ? 201.840 215.517 169.311 1.00 89.47  ? 689 PHE B CE2 1 
ATOM   11585 C  CZ  . PHE B 1 689 ? 202.437 215.617 168.073 1.00 89.47  ? 689 PHE B CZ  1 
ATOM   11586 N  N   . LYS B 1 690 ? 199.071 219.569 170.116 1.00 92.21  ? 690 LYS B N   1 
ATOM   11587 C  CA  . LYS B 1 690 ? 197.832 219.102 169.511 1.00 92.21  ? 690 LYS B CA  1 
ATOM   11588 C  C   . LYS B 1 690 ? 197.068 220.206 168.795 1.00 92.21  ? 690 LYS B C   1 
ATOM   11589 O  O   . LYS B 1 690 ? 196.017 219.920 168.211 1.00 92.21  ? 690 LYS B O   1 
ATOM   11590 C  CB  . LYS B 1 690 ? 196.935 218.465 170.574 1.00 92.21  ? 690 LYS B CB  1 
ATOM   11591 C  CG  . LYS B 1 690 ? 196.165 219.465 171.413 1.00 92.21  ? 690 LYS B CG  1 
ATOM   11592 C  CD  . LYS B 1 690 ? 195.265 218.772 172.422 1.00 92.21  ? 690 LYS B CD  1 
ATOM   11593 C  CE  . LYS B 1 690 ? 194.340 219.765 173.108 1.00 92.21  ? 690 LYS B CE  1 
ATOM   11594 N  NZ  . LYS B 1 690 ? 193.381 219.094 174.029 1.00 92.21  ? 690 LYS B NZ  1 
ATOM   11595 N  N   . ARG B 1 691 ? 197.556 221.444 168.812 1.00 88.80  ? 691 ARG B N   1 
ATOM   11596 C  CA  . ARG B 1 691 ? 196.837 222.553 168.203 1.00 88.80  ? 691 ARG B CA  1 
ATOM   11597 C  C   . ARG B 1 691 ? 197.626 223.303 167.144 1.00 88.80  ? 691 ARG B C   1 
ATOM   11598 O  O   . ARG B 1 691 ? 197.017 223.976 166.312 1.00 88.80  ? 691 ARG B O   1 
ATOM   11599 C  CB  . ARG B 1 691 ? 196.392 223.557 169.276 1.00 88.80  ? 691 ARG B CB  1 
ATOM   11600 C  CG  . ARG B 1 691 ? 197.531 224.339 169.898 1.00 88.80  ? 691 ARG B CG  1 
ATOM   11601 C  CD  . ARG B 1 691 ? 197.037 225.240 171.014 1.00 88.80  ? 691 ARG B CD  1 
ATOM   11602 N  NE  . ARG B 1 691 ? 196.545 224.479 172.156 1.00 88.80  ? 691 ARG B NE  1 
ATOM   11603 C  CZ  . ARG B 1 691 ? 195.909 225.011 173.191 1.00 88.80  ? 691 ARG B CZ  1 
ATOM   11604 N  NH1 . ARG B 1 691 ? 195.676 226.311 173.265 1.00 88.80  ? 691 ARG B NH1 1 
ATOM   11605 N  NH2 . ARG B 1 691 ? 195.497 224.219 174.176 1.00 88.80  ? 691 ARG B NH2 1 
ATOM   11606 N  N   . ILE B 1 692 ? 198.955 223.215 167.149 1.00 87.39  ? 692 ILE B N   1 
ATOM   11607 C  CA  . ILE B 1 692 ? 199.760 223.944 166.171 1.00 87.39  ? 692 ILE B CA  1 
ATOM   11608 C  C   . ILE B 1 692 ? 199.540 223.381 164.772 1.00 87.39  ? 692 ILE B C   1 
ATOM   11609 O  O   . ILE B 1 692 ? 199.959 223.978 163.771 1.00 87.39  ? 692 ILE B O   1 
ATOM   11610 C  CB  . ILE B 1 692 ? 201.249 223.927 166.556 1.00 87.39  ? 692 ILE B CB  1 
ATOM   11611 C  CG1 . ILE B 1 692 ? 201.754 222.496 166.705 1.00 87.39  ? 692 ILE B CG1 1 
ATOM   11612 C  CG2 . ILE B 1 692 ? 201.490 224.742 167.814 1.00 87.39  ? 692 ILE B CG2 1 
ATOM   11613 C  CD1 . ILE B 1 692 ? 203.235 222.425 166.933 1.00 87.39  ? 692 ILE B CD1 1 
ATOM   11614 N  N   . GLN B 1 693 ? 198.870 222.230 164.693 1.00 87.33  ? 693 GLN B N   1 
ATOM   11615 C  CA  . GLN B 1 693 ? 198.448 221.716 163.397 1.00 87.33  ? 693 GLN B CA  1 
ATOM   11616 C  C   . GLN B 1 693 ? 197.518 222.692 162.698 1.00 87.33  ? 693 GLN B C   1 
ATOM   11617 O  O   . GLN B 1 693 ? 197.463 222.720 161.466 1.00 87.33  ? 693 GLN B O   1 
ATOM   11618 C  CB  . GLN B 1 693 ? 197.756 220.366 163.565 1.00 87.33  ? 693 GLN B CB  1 
ATOM   11619 C  CG  . GLN B 1 693 ? 198.660 219.253 164.043 1.00 87.33  ? 693 GLN B CG  1 
ATOM   11620 C  CD  . GLN B 1 693 ? 199.003 219.388 165.511 1.00 87.33  ? 693 GLN B CD  1 
ATOM   11621 O  OE1 . GLN B 1 693 ? 198.464 220.250 166.207 1.00 87.33  ? 693 GLN B OE1 1 
ATOM   11622 N  NE2 . GLN B 1 693 ? 199.904 218.540 165.991 1.00 87.33  ? 693 GLN B NE2 1 
ATOM   11623 N  N   . ILE B 1 694 ? 196.777 223.496 163.464 1.00 84.61  ? 694 ILE B N   1 
ATOM   11624 C  CA  . ILE B 1 694 ? 195.925 224.518 162.864 1.00 84.61  ? 694 ILE B CA  1 
ATOM   11625 C  C   . ILE B 1 694 ? 196.774 225.527 162.105 1.00 84.61  ? 694 ILE B C   1 
ATOM   11626 O  O   . ILE B 1 694 ? 196.477 225.883 160.960 1.00 84.61  ? 694 ILE B O   1 
ATOM   11627 C  CB  . ILE B 1 694 ? 195.066 225.202 163.941 1.00 84.61  ? 694 ILE B CB  1 
ATOM   11628 C  CG1 . ILE B 1 694 ? 194.178 224.174 164.645 1.00 84.61  ? 694 ILE B CG1 1 
ATOM   11629 C  CG2 . ILE B 1 694 ? 194.222 226.306 163.327 1.00 84.61  ? 694 ILE B CG2 1 
ATOM   11630 C  CD1 . ILE B 1 694 ? 193.209 223.471 163.721 1.00 84.61  ? 694 ILE B CD1 1 
ATOM   11631 N  N   . LEU B 1 695 ? 197.860 225.988 162.727 1.00 78.34  ? 695 LEU B N   1 
ATOM   11632 C  CA  . LEU B 1 695 ? 198.776 226.891 162.039 1.00 78.34  ? 695 LEU B CA  1 
ATOM   11633 C  C   . LEU B 1 695 ? 199.402 226.210 160.831 1.00 78.34  ? 695 LEU B C   1 
ATOM   11634 O  O   . LEU B 1 695 ? 199.544 226.816 159.760 1.00 78.34  ? 695 LEU B O   1 
ATOM   11635 C  CB  . LEU B 1 695 ? 199.858 227.371 163.005 1.00 78.34  ? 695 LEU B CB  1 
ATOM   11636 C  CG  . LEU B 1 695 ? 199.387 228.290 164.131 1.00 78.34  ? 695 LEU B CG  1 
ATOM   11637 C  CD1 . LEU B 1 695 ? 200.552 228.670 165.029 1.00 78.34  ? 695 LEU B CD1 1 
ATOM   11638 C  CD2 . LEU B 1 695 ? 198.712 229.531 163.569 1.00 78.34  ? 695 LEU B CD2 1 
ATOM   11639 N  N   . ARG B 1 696 ? 199.782 224.941 160.986 1.00 74.23  ? 696 ARG B N   1 
ATOM   11640 C  CA  . ARG B 1 696 ? 200.400 224.222 159.877 1.00 74.23  ? 696 ARG B CA  1 
ATOM   11641 C  C   . ARG B 1 696 ? 199.457 224.150 158.686 1.00 74.23  ? 696 ARG B C   1 
ATOM   11642 O  O   . ARG B 1 696 ? 199.860 224.389 157.542 1.00 74.23  ? 696 ARG B O   1 
ATOM   11643 C  CB  . ARG B 1 696 ? 200.810 222.820 160.315 1.00 74.23  ? 696 ARG B CB  1 
ATOM   11644 C  CG  . ARG B 1 696 ? 201.557 222.060 159.239 1.00 74.23  ? 696 ARG B CG  1 
ATOM   11645 C  CD  . ARG B 1 696 ? 202.753 222.852 158.743 1.00 74.23  ? 696 ARG B CD  1 
ATOM   11646 N  NE  . ARG B 1 696 ? 203.514 222.133 157.729 1.00 74.23  ? 696 ARG B NE  1 
ATOM   11647 C  CZ  . ARG B 1 696 ? 203.738 222.581 156.502 1.00 74.23  ? 696 ARG B CZ  1 
ATOM   11648 N  NH1 . ARG B 1 696 ? 203.277 223.754 156.099 1.00 74.23  ? 696 ARG B NH1 1 
ATOM   11649 N  NH2 . ARG B 1 696 ? 204.445 221.835 155.659 1.00 74.23  ? 696 ARG B NH2 1 
ATOM   11650 N  N   . ASP B 1 697 ? 198.191 223.829 158.940 1.00 83.89  ? 697 ASP B N   1 
ATOM   11651 C  CA  . ASP B 1 697 ? 197.202 223.803 157.871 1.00 83.89  ? 697 ASP B CA  1 
ATOM   11652 C  C   . ASP B 1 697 ? 196.962 225.201 157.322 1.00 83.89  ? 697 ASP B C   1 
ATOM   11653 O  O   . ASP B 1 697 ? 196.637 225.367 156.141 1.00 83.89  ? 697 ASP B O   1 
ATOM   11654 C  CB  . ASP B 1 697 ? 195.897 223.191 158.380 1.00 83.89  ? 697 ASP B CB  1 
ATOM   11655 C  CG  . ASP B 1 697 ? 196.037 221.720 158.716 1.00 83.89  ? 697 ASP B CG  1 
ATOM   11656 O  OD1 . ASP B 1 697 ? 197.031 221.101 158.280 1.00 83.89  ? 697 ASP B OD1 1 
ATOM   11657 O  OD2 . ASP B 1 697 ? 195.154 221.182 159.418 1.00 83.89  ? 697 ASP B OD2 1 
ATOM   11658 N  N   . MET B 1 698 ? 197.113 226.221 158.169 1.00 78.81  ? 698 MET B N   1 
ATOM   11659 C  CA  . MET B 1 698 ? 196.994 227.589 157.693 1.00 78.81  ? 698 MET B CA  1 
ATOM   11660 C  C   . MET B 1 698 ? 198.072 227.925 156.677 1.00 78.81  ? 698 MET B C   1 
ATOM   11661 O  O   . MET B 1 698 ? 197.785 228.604 155.686 1.00 78.81  ? 698 MET B O   1 
ATOM   11662 C  CB  . MET B 1 698 ? 197.053 228.561 158.868 1.00 78.81  ? 698 MET B CB  1 
ATOM   11663 C  CG  . MET B 1 698 ? 196.489 229.927 158.548 1.00 78.81  ? 698 MET B CG  1 
ATOM   11664 S  SD  . MET B 1 698 ? 194.719 229.867 158.218 1.00 78.81  ? 698 MET B SD  1 
ATOM   11665 C  CE  . MET B 1 698 ? 194.517 231.305 157.171 1.00 78.81  ? 698 MET B CE  1 
ATOM   11666 N  N   . GLY B 1 699 ? 199.298 227.462 156.895 1.00 74.96  ? 699 GLY B N   1 
ATOM   11667 C  CA  . GLY B 1 699 ? 200.344 227.665 155.910 1.00 74.96  ? 699 GLY B CA  1 
ATOM   11668 C  C   . GLY B 1 699 ? 201.697 228.009 156.494 1.00 74.96  ? 699 GLY B C   1 
ATOM   11669 O  O   . GLY B 1 699 ? 202.692 228.099 155.768 1.00 74.96  ? 699 GLY B O   1 
ATOM   11670 N  N   . VAL B 1 700 ? 201.742 228.206 157.805 1.00 67.74  ? 700 VAL B N   1 
ATOM   11671 C  CA  . VAL B 1 700 ? 202.994 228.474 158.499 1.00 67.74  ? 700 VAL B CA  1 
ATOM   11672 C  C   . VAL B 1 700 ? 203.888 227.246 158.395 1.00 67.74  ? 700 VAL B C   1 
ATOM   11673 O  O   . VAL B 1 700 ? 203.430 226.113 158.581 1.00 67.74  ? 700 VAL B O   1 
ATOM   11674 C  CB  . VAL B 1 700 ? 202.728 228.842 159.965 1.00 67.74  ? 700 VAL B CB  1 
ATOM   11675 C  CG1 . VAL B 1 700 ? 204.000 229.340 160.629 1.00 67.74  ? 700 VAL B CG1 1 
ATOM   11676 C  CG2 . VAL B 1 700 ? 201.624 229.879 160.055 1.00 67.74  ? 700 VAL B CG2 1 
ATOM   11677 N  N   . GLY B 1 701 ? 205.164 227.465 158.091 1.00 57.29  ? 701 GLY B N   1 
ATOM   11678 C  CA  . GLY B 1 701 ? 206.122 226.378 158.023 1.00 57.29  ? 701 GLY B CA  1 
ATOM   11679 C  C   . GLY B 1 701 ? 206.467 225.815 159.386 1.00 57.29  ? 701 GLY B C   1 
ATOM   11680 O  O   . GLY B 1 701 ? 205.703 225.989 160.338 1.00 57.29  ? 701 GLY B O   1 
ATOM   11681 N  N   . LEU B 1 702 ? 207.607 225.140 159.502 1.00 53.10  ? 702 LEU B N   1 
ATOM   11682 C  CA  . LEU B 1 702 ? 208.015 224.632 160.801 1.00 53.10  ? 702 LEU B CA  1 
ATOM   11683 C  C   . LEU B 1 702 ? 209.493 224.272 160.752 1.00 53.10  ? 702 LEU B C   1 
ATOM   11684 O  O   . LEU B 1 702 ? 209.965 223.686 159.771 1.00 53.10  ? 702 LEU B O   1 
ATOM   11685 C  CB  . LEU B 1 702 ? 207.181 223.414 161.195 1.00 53.10  ? 702 LEU B CB  1 
ATOM   11686 C  CG  . LEU B 1 702 ? 206.976 223.266 162.695 1.00 53.10  ? 702 LEU B CG  1 
ATOM   11687 C  CD1 . LEU B 1 702 ? 206.115 224.418 163.154 1.00 53.10  ? 702 LEU B CD1 1 
ATOM   11688 C  CD2 . LEU B 1 702 ? 206.319 221.950 163.035 1.00 53.10  ? 702 LEU B CD2 1 
ATOM   11689 N  N   . SER B 1 703 ? 210.218 224.624 161.811 1.00 46.90  ? 703 SER B N   1 
ATOM   11690 C  CA  . SER B 1 703 ? 211.633 224.307 161.897 1.00 46.90  ? 703 SER B CA  1 
ATOM   11691 C  C   . SER B 1 703 ? 211.959 223.788 163.288 1.00 46.90  ? 703 SER B C   1 
ATOM   11692 O  O   . SER B 1 703 ? 211.306 224.131 164.276 1.00 46.90  ? 703 SER B O   1 
ATOM   11693 C  CB  . SER B 1 703 ? 212.495 225.520 161.563 1.00 46.90  ? 703 SER B CB  1 
ATOM   11694 O  OG  . SER B 1 703 ? 212.320 226.534 162.527 1.00 46.90  ? 703 SER B OG  1 
ATOM   11695 N  N   . VAL B 1 704 ? 213.001 222.963 163.351 1.00 41.89  ? 704 VAL B N   1 
ATOM   11696 C  CA  . VAL B 1 704 ? 213.371 222.251 164.561 1.00 41.89  ? 704 VAL B CA  1 
ATOM   11697 C  C   . VAL B 1 704 ? 214.870 222.423 164.780 1.00 41.89  ? 704 VAL B C   1 
ATOM   11698 O  O   . VAL B 1 704 ? 215.619 222.756 163.861 1.00 41.89  ? 704 VAL B O   1 
ATOM   11699 C  CB  . VAL B 1 704 ? 212.993 220.760 164.474 1.00 41.89  ? 704 VAL B CB  1 
ATOM   11700 C  CG1 . VAL B 1 704 ? 213.830 220.064 163.421 1.00 41.89  ? 704 VAL B CG1 1 
ATOM   11701 C  CG2 . VAL B 1 704 ? 213.099 220.073 165.819 1.00 41.89  ? 704 VAL B CG2 1 
ATOM   11702 N  N   . ASP B 1 705 ? 215.299 222.211 166.021 1.00 49.92  ? 705 ASP B N   1 
ATOM   11703 C  CA  . ASP B 1 705 ? 216.708 222.250 166.388 1.00 49.92  ? 705 ASP B CA  1 
ATOM   11704 C  C   . ASP B 1 705 ? 217.278 220.896 166.784 1.00 49.92  ? 705 ASP B C   1 
ATOM   11705 O  O   . ASP B 1 705 ? 218.402 220.580 166.393 1.00 49.92  ? 705 ASP B O   1 
ATOM   11706 C  CB  . ASP B 1 705 ? 216.932 223.230 167.548 1.00 49.92  ? 705 ASP B CB  1 
ATOM   11707 C  CG  . ASP B 1 705 ? 218.386 223.632 167.703 1.00 49.92  ? 705 ASP B CG  1 
ATOM   11708 O  OD1 . ASP B 1 705 ? 219.220 223.210 166.876 1.00 49.92  ? 705 ASP B OD1 1 
ATOM   11709 O  OD2 . ASP B 1 705 ? 218.697 224.377 168.656 1.00 49.92  ? 705 ASP B OD2 1 
ATOM   11710 N  N   . ASP B 1 706 ? 216.541 220.092 167.544 1.00 66.37  ? 706 ASP B N   1 
ATOM   11711 C  CA  . ASP B 1 706 ? 217.012 218.783 167.968 1.00 66.37  ? 706 ASP B CA  1 
ATOM   11712 C  C   . ASP B 1 706 ? 215.874 217.785 167.817 1.00 66.37  ? 706 ASP B C   1 
ATOM   11713 O  O   . ASP B 1 706 ? 214.701 218.130 167.967 1.00 66.37  ? 706 ASP B O   1 
ATOM   11714 C  CB  . ASP B 1 706 ? 217.512 218.822 169.416 1.00 66.37  ? 706 ASP B CB  1 
ATOM   11715 C  CG  . ASP B 1 706 ? 218.193 217.537 169.839 1.00 66.37  ? 706 ASP B CG  1 
ATOM   11716 O  OD1 . ASP B 1 706 ? 219.365 217.331 169.464 1.00 66.37  ? 706 ASP B OD1 1 
ATOM   11717 O  OD2 . ASP B 1 706 ? 217.559 216.736 170.557 1.00 66.37  ? 706 ASP B OD2 1 
ATOM   11718 N  N   . PHE B 1 707 ? 216.231 216.543 167.516 1.00 68.95  ? 707 PHE B N   1 
ATOM   11719 C  CA  . PHE B 1 707 ? 215.250 215.478 167.379 1.00 68.95  ? 707 PHE B CA  1 
ATOM   11720 C  C   . PHE B 1 707 ? 214.870 214.930 168.748 1.00 68.95  ? 707 PHE B C   1 
ATOM   11721 O  O   . PHE B 1 707 ? 215.685 214.897 169.673 1.00 68.95  ? 707 PHE B O   1 
ATOM   11722 C  CB  . PHE B 1 707 ? 215.788 214.350 166.497 1.00 68.95  ? 707 PHE B CB  1 
ATOM   11723 C  CG  . PHE B 1 707 ? 215.848 214.694 165.035 1.00 68.95  ? 707 PHE B CG  1 
ATOM   11724 C  CD1 . PHE B 1 707 ? 216.874 215.477 164.536 1.00 68.95  ? 707 PHE B CD1 1 
ATOM   11725 C  CD2 . PHE B 1 707 ? 214.883 214.228 164.159 1.00 68.95  ? 707 PHE B CD2 1 
ATOM   11726 C  CE1 . PHE B 1 707 ? 216.936 215.791 163.199 1.00 68.95  ? 707 PHE B CE1 1 
ATOM   11727 C  CE2 . PHE B 1 707 ? 214.939 214.541 162.816 1.00 68.95  ? 707 PHE B CE2 1 
ATOM   11728 C  CZ  . PHE B 1 707 ? 215.967 215.324 162.336 1.00 68.95  ? 707 PHE B CZ  1 
ATOM   11729 N  N   . GLY B 1 708 ? 213.623 214.486 168.869 1.00 72.68  ? 708 GLY B N   1 
ATOM   11730 C  CA  . GLY B 1 708 ? 213.085 214.042 170.140 1.00 72.68  ? 708 GLY B CA  1 
ATOM   11731 C  C   . GLY B 1 708 ? 213.584 212.679 170.564 1.00 72.68  ? 708 GLY B C   1 
ATOM   11732 O  O   . GLY B 1 708 ? 214.673 212.236 170.182 1.00 72.68  ? 708 GLY B O   1 
ATOM   11733 N  N   . THR B 1 709 ? 212.783 212.009 171.387 1.00 75.45  ? 709 THR B N   1 
ATOM   11734 C  CA  . THR B 1 709 ? 213.066 210.650 171.812 1.00 75.45  ? 709 THR B CA  1 
ATOM   11735 C  C   . THR B 1 709 ? 212.958 209.699 170.620 1.00 75.45  ? 709 THR B C   1 
ATOM   11736 O  O   . THR B 1 709 ? 212.173 209.908 169.691 1.00 75.45  ? 709 THR B O   1 
ATOM   11737 C  CB  . THR B 1 709 ? 212.108 210.234 172.928 1.00 75.45  ? 709 THR B CB  1 
ATOM   11738 O  OG1 . THR B 1 709 ? 212.145 211.212 173.974 1.00 75.45  ? 709 THR B OG1 1 
ATOM   11739 C  CG2 . THR B 1 709 ? 212.501 208.884 173.510 1.00 75.45  ? 709 THR B CG2 1 
ATOM   11740 N  N   . GLY B 1 710 ? 213.769 208.642 170.651 1.00 75.86  ? 710 GLY B N   1 
ATOM   11741 C  CA  . GLY B 1 710 ? 213.878 207.719 169.537 1.00 75.86  ? 710 GLY B CA  1 
ATOM   11742 C  C   . GLY B 1 710 ? 212.581 207.096 169.061 1.00 75.86  ? 710 GLY B C   1 
ATOM   11743 O  O   . GLY B 1 710 ? 211.769 206.622 169.861 1.00 75.86  ? 710 GLY B O   1 
ATOM   11744 N  N   . PHE B 1 711 ? 212.376 207.116 167.746 1.00 72.95  ? 711 PHE B N   1 
ATOM   11745 C  CA  . PHE B 1 711 ? 211.243 206.534 167.036 1.00 72.95  ? 711 PHE B CA  1 
ATOM   11746 C  C   . PHE B 1 711 ? 209.928 207.240 167.332 1.00 72.95  ? 711 PHE B C   1 
ATOM   11747 O  O   . PHE B 1 711 ? 208.910 206.903 166.717 1.00 72.95  ? 711 PHE B O   1 
ATOM   11748 C  CB  . PHE B 1 711 ? 211.079 205.037 167.322 1.00 72.95  ? 711 PHE B CB  1 
ATOM   11749 C  CG  . PHE B 1 711 ? 211.910 204.166 166.440 1.00 72.95  ? 711 PHE B CG  1 
ATOM   11750 C  CD1 . PHE B 1 711 ? 212.856 204.720 165.600 1.00 72.95  ? 711 PHE B CD1 1 
ATOM   11751 C  CD2 . PHE B 1 711 ? 211.734 202.797 166.434 1.00 72.95  ? 711 PHE B CD2 1 
ATOM   11752 C  CE1 . PHE B 1 711 ? 213.619 203.923 164.782 1.00 72.95  ? 711 PHE B CE1 1 
ATOM   11753 C  CE2 . PHE B 1 711 ? 212.493 201.994 165.618 1.00 72.95  ? 711 PHE B CE2 1 
ATOM   11754 C  CZ  . PHE B 1 711 ? 213.438 202.557 164.790 1.00 72.95  ? 711 PHE B CZ  1 
ATOM   11755 N  N   . SER B 1 712 ? 209.910 208.209 168.238 1.00 80.10  ? 712 SER B N   1 
ATOM   11756 C  CA  . SER B 1 712 ? 208.730 209.019 168.496 1.00 80.10  ? 712 SER B CA  1 
ATOM   11757 C  C   . SER B 1 712 ? 208.965 210.489 168.215 1.00 80.10  ? 712 SER B C   1 
ATOM   11758 O  O   . SER B 1 712 ? 208.040 211.193 167.806 1.00 80.10  ? 712 SER B O   1 
ATOM   11759 C  CB  . SER B 1 712 ? 208.277 208.848 169.950 1.00 80.10  ? 712 SER B CB  1 
ATOM   11760 O  OG  . SER B 1 712 ? 207.891 207.509 170.210 1.00 80.10  ? 712 SER B OG  1 
ATOM   11761 N  N   . GLY B 1 713 ? 210.191 210.959 168.415 1.00 81.94  ? 713 GLY B N   1 
ATOM   11762 C  CA  . GLY B 1 713 ? 210.541 212.327 168.105 1.00 81.94  ? 713 GLY B CA  1 
ATOM   11763 C  C   . GLY B 1 713 ? 211.009 212.455 166.674 1.00 81.94  ? 713 GLY B C   1 
ATOM   11764 O  O   . GLY B 1 713 ? 211.639 213.450 166.302 1.00 81.94  ? 713 GLY B O   1 
ATOM   11765 N  N   . LEU B 1 714 ? 210.705 211.447 165.858 1.00 82.16  ? 714 LEU B N   1 
ATOM   11766 C  CA  . LEU B 1 714 ? 211.101 211.464 164.458 1.00 82.16  ? 714 LEU B CA  1 
ATOM   11767 C  C   . LEU B 1 714 ? 210.198 212.407 163.677 1.00 82.16  ? 714 LEU B C   1 
ATOM   11768 O  O   . LEU B 1 714 ? 209.524 211.986 162.735 1.00 82.16  ? 714 LEU B O   1 
ATOM   11769 C  CB  . LEU B 1 714 ? 211.042 210.057 163.867 1.00 82.16  ? 714 LEU B CB  1 
ATOM   11770 C  CG  . LEU B 1 714 ? 211.911 209.825 162.631 1.00 82.16  ? 714 LEU B CG  1 
ATOM   11771 C  CD1 . LEU B 1 714 ? 213.371 209.693 163.021 1.00 82.16  ? 714 LEU B CD1 1 
ATOM   11772 C  CD2 . LEU B 1 714 ? 211.444 208.596 161.872 1.00 82.16  ? 714 LEU B CD2 1 
ATOM   11773 N  N   . SER B 1 715 ? 210.182 213.687 164.057 1.00 78.28  ? 715 SER B N   1 
ATOM   11774 C  CA  . SER B 1 715 ? 209.198 214.642 163.548 1.00 78.28  ? 715 SER B CA  1 
ATOM   11775 C  C   . SER B 1 715 ? 207.785 214.119 163.781 1.00 78.28  ? 715 SER B C   1 
ATOM   11776 O  O   . SER B 1 715 ? 206.887 214.282 162.952 1.00 78.28  ? 715 SER B O   1 
ATOM   11777 C  CB  . SER B 1 715 ? 209.438 214.951 162.074 1.00 78.28  ? 715 SER B CB  1 
ATOM   11778 O  OG  . SER B 1 715 ? 210.765 215.402 161.873 1.00 78.28  ? 715 SER B OG  1 
ATOM   11779 N  N   . ARG B 1 716 ? 207.598 213.483 164.938 1.00 82.83  ? 716 ARG B N   1 
ATOM   11780 C  CA  . ARG B 1 716 ? 206.346 212.826 165.295 1.00 82.83  ? 716 ARG B CA  1 
ATOM   11781 C  C   . ARG B 1 716 ? 205.942 211.820 164.224 1.00 82.83  ? 716 ARG B C   1 
ATOM   11782 O  O   . ARG B 1 716 ? 204.784 211.751 163.815 1.00 82.83  ? 716 ARG B O   1 
ATOM   11783 C  CB  . ARG B 1 716 ? 205.237 213.852 165.531 1.00 82.83  ? 716 ARG B CB  1 
ATOM   11784 C  CG  . ARG B 1 716 ? 205.664 215.044 166.358 1.00 82.83  ? 716 ARG B CG  1 
ATOM   11785 C  CD  . ARG B 1 716 ? 206.271 214.620 167.684 1.00 82.83  ? 716 ARG B CD  1 
ATOM   11786 N  NE  . ARG B 1 716 ? 205.254 214.211 168.644 1.00 82.83  ? 716 ARG B NE  1 
ATOM   11787 C  CZ  . ARG B 1 716 ? 205.109 212.975 169.100 1.00 82.83  ? 716 ARG B CZ  1 
ATOM   11788 N  NH1 . ARG B 1 716 ? 205.909 211.997 168.710 1.00 82.83  ? 716 ARG B NH1 1 
ATOM   11789 N  NH2 . ARG B 1 716 ? 204.138 212.714 169.971 1.00 82.83  ? 716 ARG B NH2 1 
ATOM   11790 N  N   . LEU B 1 717 ? 206.912 211.023 163.779 1.00 86.52  ? 717 LEU B N   1 
ATOM   11791 C  CA  . LEU B 1 717 ? 206.737 210.171 162.602 1.00 86.52  ? 717 LEU B CA  1 
ATOM   11792 C  C   . LEU B 1 717 ? 206.353 211.023 161.394 1.00 86.52  ? 717 LEU B C   1 
ATOM   11793 O  O   . LEU B 1 717 ? 205.373 210.748 160.700 1.00 86.52  ? 717 LEU B O   1 
ATOM   11794 C  CB  . LEU B 1 717 ? 205.706 209.067 162.852 1.00 86.52  ? 717 LEU B CB  1 
ATOM   11795 C  CG  . LEU B 1 717 ? 206.188 207.847 163.638 1.00 86.52  ? 717 LEU B CG  1 
ATOM   11796 C  CD1 . LEU B 1 717 ? 205.159 206.732 163.566 1.00 86.52  ? 717 LEU B CD1 1 
ATOM   11797 C  CD2 . LEU B 1 717 ? 207.538 207.372 163.124 1.00 86.52  ? 717 LEU B CD2 1 
ATOM   11798 N  N   . VAL B 1 718 ? 207.128 212.089 161.185 1.00 80.58  ? 718 VAL B N   1 
ATOM   11799 C  CA  . VAL B 1 718 ? 206.968 213.124 160.161 1.00 80.58  ? 718 VAL B CA  1 
ATOM   11800 C  C   . VAL B 1 718 ? 205.501 213.531 160.052 1.00 80.58  ? 718 VAL B C   1 
ATOM   11801 O  O   . VAL B 1 718 ? 205.041 213.994 159.003 1.00 80.58  ? 718 VAL B O   1 
ATOM   11802 C  CB  . VAL B 1 718 ? 207.551 212.679 158.799 1.00 80.58  ? 718 VAL B CB  1 
ATOM   11803 C  CG1 . VAL B 1 718 ? 206.721 211.582 158.127 1.00 80.58  ? 718 VAL B CG1 1 
ATOM   11804 C  CG2 . VAL B 1 718 ? 207.800 213.876 157.876 1.00 80.58  ? 718 VAL B CG2 1 
ATOM   11805 N  N   . SER B 1 719 ? 204.762 213.395 161.151 1.00 79.02  ? 719 SER B N   1 
ATOM   11806 C  CA  . SER B 1 719 ? 203.351 213.753 161.131 1.00 79.02  ? 719 SER B CA  1 
ATOM   11807 C  C   . SER B 1 719 ? 203.214 215.261 161.020 1.00 79.02  ? 719 SER B C   1 
ATOM   11808 O  O   . SER B 1 719 ? 202.679 215.772 160.033 1.00 79.02  ? 719 SER B O   1 
ATOM   11809 C  CB  . SER B 1 719 ? 202.630 213.245 162.380 1.00 79.02  ? 719 SER B CB  1 
ATOM   11810 O  OG  . SER B 1 719 ? 202.775 211.843 162.516 1.00 79.02  ? 719 SER B OG  1 
ATOM   11811 N  N   . LEU B 1 720 ? 203.701 215.972 162.023 1.00 71.52  ? 720 LEU B N   1 
ATOM   11812 C  CA  . LEU B 1 720 ? 203.777 217.420 161.961 1.00 71.52  ? 720 LEU B CA  1 
ATOM   11813 C  C   . LEU B 1 720 ? 204.738 217.780 160.841 1.00 71.52  ? 720 LEU B C   1 
ATOM   11814 O  O   . LEU B 1 720 ? 205.948 217.562 160.970 1.00 71.52  ? 720 LEU B O   1 
ATOM   11815 C  CB  . LEU B 1 720 ? 204.251 217.986 163.293 1.00 71.52  ? 720 LEU B CB  1 
ATOM   11816 C  CG  . LEU B 1 720 ? 203.743 219.361 163.697 1.00 71.52  ? 720 LEU B CG  1 
ATOM   11817 C  CD1 . LEU B 1 720 ? 202.230 219.410 163.646 1.00 71.52  ? 720 LEU B CD1 1 
ATOM   11818 C  CD2 . LEU B 1 720 ? 204.245 219.664 165.088 1.00 71.52  ? 720 LEU B CD2 1 
ATOM   11819 N  N   . PRO B 1 721 ? 204.252 218.321 159.738 1.00 62.63  ? 721 PRO B N   1 
ATOM   11820 C  CA  . PRO B 1 721 ? 205.114 218.479 158.565 1.00 62.63  ? 721 PRO B CA  1 
ATOM   11821 C  C   . PRO B 1 721 ? 206.183 219.524 158.800 1.00 62.63  ? 721 PRO B C   1 
ATOM   11822 O  O   . PRO B 1 721 ? 206.099 220.640 158.280 1.00 62.63  ? 721 PRO B O   1 
ATOM   11823 C  CB  . PRO B 1 721 ? 204.142 218.906 157.459 1.00 62.63  ? 721 PRO B CB  1 
ATOM   11824 C  CG  . PRO B 1 721 ? 202.769 218.652 158.010 1.00 62.63  ? 721 PRO B CG  1 
ATOM   11825 C  CD  . PRO B 1 721 ? 202.892 218.813 159.485 1.00 62.63  ? 721 PRO B CD  1 
ATOM   11826 N  N   . VAL B 1 722 ? 207.188 219.171 159.598 1.00 55.29  ? 722 VAL B N   1 
ATOM   11827 C  CA  . VAL B 1 722 ? 208.353 220.023 159.780 1.00 55.29  ? 722 VAL B CA  1 
ATOM   11828 C  C   . VAL B 1 722 ? 209.005 220.192 158.421 1.00 55.29  ? 722 VAL B C   1 
ATOM   11829 O  O   . VAL B 1 722 ? 208.973 219.283 157.588 1.00 55.29  ? 722 VAL B O   1 
ATOM   11830 C  CB  . VAL B 1 722 ? 209.346 219.436 160.794 1.00 55.29  ? 722 VAL B CB  1 
ATOM   11831 C  CG1 . VAL B 1 722 ? 208.780 219.501 162.199 1.00 55.29  ? 722 VAL B CG1 1 
ATOM   11832 C  CG2 . VAL B 1 722 ? 209.687 218.015 160.420 1.00 55.29  ? 722 VAL B CG2 1 
ATOM   11833 N  N   . THR B 1 723 ? 209.581 221.359 158.180 1.00 48.53  ? 723 THR B N   1 
ATOM   11834 C  CA  . THR B 1 723 ? 210.240 221.632 156.917 1.00 48.53  ? 723 THR B CA  1 
ATOM   11835 C  C   . THR B 1 723 ? 211.723 221.930 157.053 1.00 48.53  ? 723 THR B C   1 
ATOM   11836 O  O   . THR B 1 723 ? 212.484 221.581 156.140 1.00 48.53  ? 723 THR B O   1 
ATOM   11837 C  CB  . THR B 1 723 ? 209.557 222.806 156.203 1.00 48.53  ? 723 THR B CB  1 
ATOM   11838 O  OG1 . THR B 1 723 ? 208.142 222.600 156.204 1.00 48.53  ? 723 THR B OG1 1 
ATOM   11839 C  CG2 . THR B 1 723 ? 210.033 222.913 154.768 1.00 48.53  ? 723 THR B CG2 1 
ATOM   11840 N  N   . GLU B 1 724 ? 212.167 222.532 158.154 1.00 46.59  ? 724 GLU B N   1 
ATOM   11841 C  CA  . GLU B 1 724 ? 213.562 222.920 158.286 1.00 46.59  ? 724 GLU B CA  1 
ATOM   11842 C  C   . GLU B 1 724 ? 214.182 222.293 159.521 1.00 46.59  ? 724 GLU B C   1 
ATOM   11843 O  O   . GLU B 1 724 ? 213.554 222.245 160.582 1.00 46.59  ? 724 GLU B O   1 
ATOM   11844 C  CB  . GLU B 1 724 ? 213.704 224.440 158.361 1.00 46.59  ? 724 GLU B CB  1 
ATOM   11845 C  CG  . GLU B 1 724 ? 212.723 225.198 157.505 1.00 46.59  ? 724 GLU B CG  1 
ATOM   11846 C  CD  . GLU B 1 724 ? 213.065 226.668 157.409 1.00 46.59  ? 724 GLU B CD  1 
ATOM   11847 O  OE1 . GLU B 1 724 ? 213.690 227.193 158.353 1.00 46.59  ? 724 GLU B OE1 1 
ATOM   11848 O  OE2 . GLU B 1 724 ? 212.710 227.297 156.390 1.00 46.59  ? 724 GLU B OE2 1 
ATOM   11849 N  N   . ILE B 1 725 ? 215.403 221.821 159.378 1.00 40.15  ? 725 ILE B N   1 
ATOM   11850 C  CA  . ILE B 1 725 ? 216.248 221.478 160.512 1.00 40.15  ? 725 ILE B CA  1 
ATOM   11851 C  C   . ILE B 1 725 ? 217.364 222.502 160.574 1.00 40.15  ? 725 ILE B C   1 
ATOM   11852 O  O   . ILE B 1 725 ? 217.956 222.845 159.543 1.00 40.15  ? 725 ILE B O   1 
ATOM   11853 C  CB  . ILE B 1 725 ? 216.813 220.053 160.380 1.00 40.15  ? 725 ILE B CB  1 
ATOM   11854 C  CG1 . ILE B 1 725 ? 215.763 219.105 159.825 1.00 40.15  ? 725 ILE B CG1 1 
ATOM   11855 C  CG2 . ILE B 1 725 ? 217.294 219.551 161.718 1.00 40.15  ? 725 ILE B CG2 1 
ATOM   11856 C  CD1 . ILE B 1 725 ? 216.291 217.722 159.609 1.00 40.15  ? 725 ILE B CD1 1 
ATOM   11857 N  N   . LYS B 1 726 ? 217.658 222.993 161.771 1.00 35.94  ? 726 LYS B N   1 
ATOM   11858 C  CA  . LYS B 1 726 ? 218.658 224.037 161.961 1.00 35.94  ? 726 LYS B CA  1 
ATOM   11859 C  C   . LYS B 1 726 ? 219.822 223.463 162.755 1.00 35.94  ? 726 LYS B C   1 
ATOM   11860 O  O   . LYS B 1 726 ? 219.741 223.332 163.979 1.00 35.94  ? 726 LYS B O   1 
ATOM   11861 C  CB  . LYS B 1 726 ? 218.064 225.239 162.680 1.00 35.94  ? 726 LYS B CB  1 
ATOM   11862 C  CG  . LYS B 1 726 ? 216.790 225.782 162.064 1.00 35.94  ? 726 LYS B CG  1 
ATOM   11863 C  CD  . LYS B 1 726 ? 216.748 227.300 162.148 1.00 35.94  ? 726 LYS B CD  1 
ATOM   11864 C  CE  . LYS B 1 726 ? 215.755 227.873 161.156 1.00 35.94  ? 726 LYS B CE  1 
ATOM   11865 N  NZ  . LYS B 1 726 ? 215.764 229.355 161.157 1.00 35.94  ? 726 LYS B NZ  1 
ATOM   11866 N  N   . ILE B 1 727 ? 220.912 223.137 162.069 1.00 38.79  ? 727 ILE B N   1 
ATOM   11867 C  CA  . ILE B 1 727 ? 222.127 222.724 162.759 1.00 38.79  ? 727 ILE B CA  1 
ATOM   11868 C  C   . ILE B 1 727 ? 222.684 223.944 163.484 1.00 38.79  ? 727 ILE B C   1 
ATOM   11869 O  O   . ILE B 1 727 ? 223.217 224.864 162.855 1.00 38.79  ? 727 ILE B O   1 
ATOM   11870 C  CB  . ILE B 1 727 ? 223.153 222.138 161.792 1.00 38.79  ? 727 ILE B CB  1 
ATOM   11871 C  CG1 . ILE B 1 727 ? 222.543 220.970 161.031 1.00 38.79  ? 727 ILE B CG1 1 
ATOM   11872 C  CG2 . ILE B 1 727 ? 224.384 221.692 162.546 1.00 38.79  ? 727 ILE B CG2 1 
ATOM   11873 C  CD1 . ILE B 1 727 ? 223.291 220.630 159.782 1.00 38.79  ? 727 ILE B CD1 1 
ATOM   11874 N  N   . ASP B 1 728 ? 222.577 223.943 164.809 1.00 46.23  ? 728 ASP B N   1 
ATOM   11875 C  CA  . ASP B 1 728 ? 222.884 225.123 165.597 1.00 46.23  ? 728 ASP B CA  1 
ATOM   11876 C  C   . ASP B 1 728 ? 224.384 225.395 165.615 1.00 46.23  ? 728 ASP B C   1 
ATOM   11877 O  O   . ASP B 1 728 ? 225.202 224.585 165.175 1.00 46.23  ? 728 ASP B O   1 
ATOM   11878 C  CB  . ASP B 1 728 ? 222.359 224.965 167.022 1.00 46.23  ? 728 ASP B CB  1 
ATOM   11879 C  CG  . ASP B 1 728 ? 222.817 223.677 167.672 1.00 46.23  ? 728 ASP B CG  1 
ATOM   11880 O  OD1 . ASP B 1 728 ? 223.443 222.849 166.978 1.00 46.23  ? 728 ASP B OD1 1 
ATOM   11881 O  OD2 . ASP B 1 728 ? 222.552 223.491 168.879 1.00 46.23  ? 728 ASP B OD2 1 
ATOM   11882 N  N   . LYS B 1 729 ? 224.737 226.568 166.144 1.00 52.61  ? 729 LYS B N   1 
ATOM   11883 C  CA  . LYS B 1 729 ? 226.121 227.028 166.100 1.00 52.61  ? 729 LYS B CA  1 
ATOM   11884 C  C   . LYS B 1 729 ? 227.042 226.155 166.934 1.00 52.61  ? 729 LYS B C   1 
ATOM   11885 O  O   . LYS B 1 729 ? 228.235 226.045 166.626 1.00 52.61  ? 729 LYS B O   1 
ATOM   11886 C  CB  . LYS B 1 729 ? 226.211 228.479 166.574 1.00 52.61  ? 729 LYS B CB  1 
ATOM   11887 C  CG  . LYS B 1 729 ? 227.627 229.032 166.614 1.00 52.61  ? 729 LYS B CG  1 
ATOM   11888 C  CD  . LYS B 1 729 ? 227.660 230.446 167.157 1.00 52.61  ? 729 LYS B CD  1 
ATOM   11889 C  CE  . LYS B 1 729 ? 229.085 230.882 167.445 1.00 52.61  ? 729 LYS B CE  1 
ATOM   11890 N  NZ  . LYS B 1 729 ? 229.894 230.977 166.200 1.00 52.61  ? 729 LYS B NZ  1 
ATOM   11891 N  N   . SER B 1 730 ? 226.515 225.526 167.984 1.00 50.83  ? 730 SER B N   1 
ATOM   11892 C  CA  . SER B 1 730 ? 227.371 224.755 168.878 1.00 50.83  ? 730 SER B CA  1 
ATOM   11893 C  C   . SER B 1 730 ? 228.106 223.648 168.138 1.00 50.83  ? 730 SER B C   1 
ATOM   11894 O  O   . SER B 1 730 ? 229.218 223.276 168.526 1.00 50.83  ? 730 SER B O   1 
ATOM   11895 C  CB  . SER B 1 730 ? 226.543 224.171 170.023 1.00 50.83  ? 730 SER B CB  1 
ATOM   11896 O  OG  . SER B 1 730 ? 225.680 223.147 169.560 1.00 50.83  ? 730 SER B OG  1 
ATOM   11897 N  N   . PHE B 1 731 ? 227.515 223.122 167.068 1.00 50.49  ? 731 PHE B N   1 
ATOM   11898 C  CA  . PHE B 1 731 ? 228.145 222.049 166.315 1.00 50.49  ? 731 PHE B CA  1 
ATOM   11899 C  C   . PHE B 1 731 ? 228.983 222.563 165.155 1.00 50.49  ? 731 PHE B C   1 
ATOM   11900 O  O   . PHE B 1 731 ? 230.050 222.008 164.875 1.00 50.49  ? 731 PHE B O   1 
ATOM   11901 C  CB  . PHE B 1 731 ? 227.086 221.077 165.793 1.00 50.49  ? 731 PHE B CB  1 
ATOM   11902 C  CG  . PHE B 1 731 ? 226.370 220.332 166.872 1.00 50.49  ? 731 PHE B CG  1 
ATOM   11903 C  CD1 . PHE B 1 731 ? 227.065 219.793 167.932 1.00 50.49  ? 731 PHE B CD1 1 
ATOM   11904 C  CD2 . PHE B 1 731 ? 225.004 220.160 166.821 1.00 50.49  ? 731 PHE B CD2 1 
ATOM   11905 C  CE1 . PHE B 1 731 ? 226.409 219.108 168.926 1.00 50.49  ? 731 PHE B CE1 1 
ATOM   11906 C  CE2 . PHE B 1 731 ? 224.345 219.478 167.812 1.00 50.49  ? 731 PHE B CE2 1 
ATOM   11907 C  CZ  . PHE B 1 731 ? 225.048 218.950 168.863 1.00 50.49  ? 731 PHE B CZ  1 
ATOM   11908 N  N   . VAL B 1 732 ? 228.517 223.600 164.457 1.00 52.12  ? 732 VAL B N   1 
ATOM   11909 C  CA  . VAL B 1 732 ? 229.270 224.129 163.327 1.00 52.12  ? 732 VAL B CA  1 
ATOM   11910 C  C   . VAL B 1 732 ? 230.521 224.867 163.767 1.00 52.12  ? 732 VAL B C   1 
ATOM   11911 O  O   . VAL B 1 732 ? 231.468 224.984 162.985 1.00 52.12  ? 732 VAL B O   1 
ATOM   11912 C  CB  . VAL B 1 732 ? 228.377 225.040 162.465 1.00 52.12  ? 732 VAL B CB  1 
ATOM   11913 C  CG1 . VAL B 1 732 ? 229.051 225.354 161.146 1.00 52.12  ? 732 VAL B CG1 1 
ATOM   11914 C  CG2 . VAL B 1 732 ? 227.039 224.374 162.222 1.00 52.12  ? 732 VAL B CG2 1 
ATOM   11915 N  N   . ASP B 1 733 ? 230.564 225.355 165.006 1.00 59.48  ? 733 ASP B N   1 
ATOM   11916 C  CA  . ASP B 1 733 ? 231.799 225.940 165.508 1.00 59.48  ? 733 ASP B CA  1 
ATOM   11917 C  C   . ASP B 1 733 ? 232.883 224.894 165.724 1.00 59.48  ? 733 ASP B C   1 
ATOM   11918 O  O   . ASP B 1 733 ? 234.067 225.213 165.590 1.00 59.48  ? 733 ASP B O   1 
ATOM   11919 C  CB  . ASP B 1 733 ? 231.535 226.692 166.813 1.00 59.48  ? 733 ASP B CB  1 
ATOM   11920 C  CG  . ASP B 1 733 ? 232.757 227.438 167.313 1.00 59.48  ? 733 ASP B CG  1 
ATOM   11921 O  OD1 . ASP B 1 733 ? 233.426 228.103 166.495 1.00 59.48  ? 733 ASP B OD1 1 
ATOM   11922 O  OD2 . ASP B 1 733 ? 233.050 227.358 168.525 1.00 59.48  ? 733 ASP B OD2 1 
ATOM   11923 N  N   . ARG B 1 734 ? 232.508 223.657 166.049 1.00 62.98  ? 734 ARG B N   1 
ATOM   11924 C  CA  . ARG B 1 734 ? 233.468 222.598 166.313 1.00 62.98  ? 734 ARG B CA  1 
ATOM   11925 C  C   . ARG B 1 734 ? 233.614 221.608 165.169 1.00 62.98  ? 734 ARG B C   1 
ATOM   11926 O  O   . ARG B 1 734 ? 234.443 220.697 165.267 1.00 62.98  ? 734 ARG B O   1 
ATOM   11927 C  CB  . ARG B 1 734 ? 233.078 221.835 167.586 1.00 62.98  ? 734 ARG B CB  1 
ATOM   11928 C  CG  . ARG B 1 734 ? 232.565 222.720 168.710 1.00 62.98  ? 734 ARG B CG  1 
ATOM   11929 C  CD  . ARG B 1 734 ? 232.674 222.019 170.055 1.00 62.98  ? 734 ARG B CD  1 
ATOM   11930 N  NE  . ARG B 1 734 ? 232.215 220.637 169.989 1.00 62.98  ? 734 ARG B NE  1 
ATOM   11931 C  CZ  . ARG B 1 734 ? 231.698 219.969 171.011 1.00 62.98  ? 734 ARG B CZ  1 
ATOM   11932 N  NH1 . ARG B 1 734 ? 231.557 220.528 172.202 1.00 62.98  ? 734 ARG B NH1 1 
ATOM   11933 N  NH2 . ARG B 1 734 ? 231.312 218.708 170.834 1.00 62.98  ? 734 ARG B NH2 1 
ATOM   11934 N  N   . CYS B 1 735 ? 232.827 221.749 164.102 1.00 65.03  ? 735 CYS B N   1 
ATOM   11935 C  CA  . CYS B 1 735 ? 232.929 220.827 162.975 1.00 65.03  ? 735 CYS B CA  1 
ATOM   11936 C  C   . CYS B 1 735 ? 234.330 220.810 162.381 1.00 65.03  ? 735 CYS B C   1 
ATOM   11937 O  O   . CYS B 1 735 ? 234.780 219.782 161.864 1.00 65.03  ? 735 CYS B O   1 
ATOM   11938 C  CB  . CYS B 1 735 ? 231.905 221.201 161.903 1.00 65.03  ? 735 CYS B CB  1 
ATOM   11939 S  SG  . CYS B 1 735 ? 231.930 220.144 160.438 1.00 65.03  ? 735 CYS B SG  1 
ATOM   11940 N  N   . LEU B 1 736 ? 235.032 221.942 162.438 1.00 65.90  ? 736 LEU B N   1 
ATOM   11941 C  CA  . LEU B 1 736 ? 236.374 222.007 161.871 1.00 65.90  ? 736 LEU B CA  1 
ATOM   11942 C  C   . LEU B 1 736 ? 237.339 221.092 162.612 1.00 65.90  ? 736 LEU B C   1 
ATOM   11943 O  O   . LEU B 1 736 ? 238.192 220.445 161.994 1.00 65.90  ? 736 LEU B O   1 
ATOM   11944 C  CB  . LEU B 1 736 ? 236.881 223.448 161.893 1.00 65.90  ? 736 LEU B CB  1 
ATOM   11945 C  CG  . LEU B 1 736 ? 238.319 223.674 161.421 1.00 65.90  ? 736 LEU B CG  1 
ATOM   11946 C  CD1 . LEU B 1 736 ? 238.480 223.257 159.968 1.00 65.90  ? 736 LEU B CD1 1 
ATOM   11947 C  CD2 . LEU B 1 736 ? 238.726 225.127 161.615 1.00 65.90  ? 736 LEU B CD2 1 
ATOM   11948 N  N   . THR B 1 737 ? 237.220 221.021 163.935 1.00 71.44  ? 737 THR B N   1 
ATOM   11949 C  CA  . THR B 1 737 ? 238.206 220.330 164.753 1.00 71.44  ? 737 THR B CA  1 
ATOM   11950 C  C   . THR B 1 737 ? 237.838 218.889 165.088 1.00 71.44  ? 737 THR B C   1 
ATOM   11951 O  O   . THR B 1 737 ? 238.651 218.197 165.711 1.00 71.44  ? 737 THR B O   1 
ATOM   11952 C  CB  . THR B 1 737 ? 238.436 221.099 166.058 1.00 71.44  ? 737 THR B CB  1 
ATOM   11953 O  OG1 . THR B 1 737 ? 237.174 221.380 166.677 1.00 71.44  ? 737 THR B OG1 1 
ATOM   11954 C  CG2 . THR B 1 737 ? 239.163 222.407 165.784 1.00 71.44  ? 737 THR B CG2 1 
ATOM   11955 N  N   . GLU B 1 738 ? 236.654 218.411 164.704 1.00 70.98  ? 738 GLU B N   1 
ATOM   11956 C  CA  . GLU B 1 738 ? 236.206 217.078 165.108 1.00 70.98  ? 738 GLU B CA  1 
ATOM   11957 C  C   . GLU B 1 738 ? 235.534 216.371 163.939 1.00 70.98  ? 738 GLU B C   1 
ATOM   11958 O  O   . GLU B 1 738 ? 234.398 216.697 163.575 1.00 70.98  ? 738 GLU B O   1 
ATOM   11959 C  CB  . GLU B 1 738 ? 235.255 217.155 166.304 1.00 70.98  ? 738 GLU B CB  1 
ATOM   11960 C  CG  . GLU B 1 738 ? 235.904 217.631 167.591 1.00 70.98  ? 738 GLU B CG  1 
ATOM   11961 C  CD  . GLU B 1 738 ? 235.074 217.302 168.815 1.00 70.98  ? 738 GLU B CD  1 
ATOM   11962 O  OE1 . GLU B 1 738 ? 234.466 216.212 168.845 1.00 70.98  ? 738 GLU B OE1 1 
ATOM   11963 O  OE2 . GLU B 1 738 ? 235.030 218.132 169.747 1.00 70.98  ? 738 GLU B OE2 1 
ATOM   11964 N  N   . LYS B 1 739 ? 236.225 215.381 163.368 1.00 70.01  ? 739 LYS B N   1 
ATOM   11965 C  CA  . LYS B 1 739 ? 235.567 214.463 162.448 1.00 70.01  ? 739 LYS B CA  1 
ATOM   11966 C  C   . LYS B 1 739 ? 234.479 213.662 163.147 1.00 70.01  ? 739 LYS B C   1 
ATOM   11967 O  O   . LYS B 1 739 ? 233.548 213.185 162.488 1.00 70.01  ? 739 LYS B O   1 
ATOM   11968 C  CB  . LYS B 1 739 ? 236.591 213.522 161.814 1.00 70.01  ? 739 LYS B CB  1 
ATOM   11969 C  CG  . LYS B 1 739 ? 237.481 212.804 162.815 1.00 70.01  ? 739 LYS B CG  1 
ATOM   11970 C  CD  . LYS B 1 739 ? 238.392 211.802 162.124 1.00 70.01  ? 739 LYS B CD  1 
ATOM   11971 C  CE  . LYS B 1 739 ? 239.377 212.499 161.199 1.00 70.01  ? 739 LYS B CE  1 
ATOM   11972 N  NZ  . LYS B 1 739 ? 240.402 213.271 161.955 1.00 70.01  ? 739 LYS B NZ  1 
ATOM   11973 N  N   . ARG B 1 740 ? 234.571 213.519 164.470 1.00 68.62  ? 740 ARG B N   1 
ATOM   11974 C  CA  . ARG B 1 740 ? 233.494 212.902 165.234 1.00 68.62  ? 740 ARG B CA  1 
ATOM   11975 C  C   . ARG B 1 740 ? 232.188 213.658 165.037 1.00 68.62  ? 740 ARG B C   1 
ATOM   11976 O  O   . ARG B 1 740 ? 231.142 213.058 164.771 1.00 68.62  ? 740 ARG B O   1 
ATOM   11977 C  CB  . ARG B 1 740 ? 233.880 212.860 166.712 1.00 68.62  ? 740 ARG B CB  1 
ATOM   11978 C  CG  . ARG B 1 740 ? 232.990 212.001 167.577 1.00 68.62  ? 740 ARG B CG  1 
ATOM   11979 C  CD  . ARG B 1 740 ? 232.098 212.849 168.469 1.00 68.62  ? 740 ARG B CD  1 
ATOM   11980 N  NE  . ARG B 1 740 ? 232.867 213.639 169.424 1.00 68.62  ? 740 ARG B NE  1 
ATOM   11981 C  CZ  . ARG B 1 740 ? 232.337 214.484 170.296 1.00 68.62  ? 740 ARG B CZ  1 
ATOM   11982 N  NH1 . ARG B 1 740 ? 231.029 214.671 170.371 1.00 68.62  ? 740 ARG B NH1 1 
ATOM   11983 N  NH2 . ARG B 1 740 ? 233.138 215.158 171.117 1.00 68.62  ? 740 ARG B NH2 1 
ATOM   11984 N  N   . ILE B 1 741 ? 232.234 214.983 165.155 1.00 62.69  ? 741 ILE B N   1 
ATOM   11985 C  CA  . ILE B 1 741 ? 231.048 215.789 164.906 1.00 62.69  ? 741 ILE B CA  1 
ATOM   11986 C  C   . ILE B 1 741 ? 230.742 215.838 163.415 1.00 62.69  ? 741 ILE B C   1 
ATOM   11987 O  O   . ILE B 1 741 ? 229.577 215.929 163.011 1.00 62.69  ? 741 ILE B O   1 
ATOM   11988 C  CB  . ILE B 1 741 ? 231.231 217.194 165.501 1.00 62.69  ? 741 ILE B CB  1 
ATOM   11989 C  CG1 . ILE B 1 741 ? 231.428 217.095 167.008 1.00 62.69  ? 741 ILE B CG1 1 
ATOM   11990 C  CG2 . ILE B 1 741 ? 230.023 218.051 165.228 1.00 62.69  ? 741 ILE B CG2 1 
ATOM   11991 C  CD1 . ILE B 1 741 ? 230.221 216.563 167.728 1.00 62.69  ? 741 ILE B CD1 1 
ATOM   11992 N  N   . LEU B 1 742 ? 231.780 215.797 162.575 1.00 62.32  ? 742 LEU B N   1 
ATOM   11993 C  CA  . LEU B 1 742 ? 231.556 215.796 161.131 1.00 62.32  ? 742 LEU B CA  1 
ATOM   11994 C  C   . LEU B 1 742 ? 230.710 214.605 160.705 1.00 62.32  ? 742 LEU B C   1 
ATOM   11995 O  O   . LEU B 1 742 ? 229.898 214.705 159.778 1.00 62.32  ? 742 LEU B O   1 
ATOM   11996 C  CB  . LEU B 1 742 ? 232.894 215.791 160.391 1.00 62.32  ? 742 LEU B CB  1 
ATOM   11997 C  CG  . LEU B 1 742 ? 232.856 215.903 158.866 1.00 62.32  ? 742 LEU B CG  1 
ATOM   11998 C  CD1 . LEU B 1 742 ? 233.983 216.792 158.376 1.00 62.32  ? 742 LEU B CD1 1 
ATOM   11999 C  CD2 . LEU B 1 742 ? 232.950 214.529 158.222 1.00 62.32  ? 742 LEU B CD2 1 
ATOM   12000 N  N   . ALA B 1 743 ? 230.896 213.466 161.366 1.00 62.37  ? 743 ALA B N   1 
ATOM   12001 C  CA  . ALA B 1 743 ? 230.102 212.287 161.040 1.00 62.37  ? 743 ALA B CA  1 
ATOM   12002 C  C   . ALA B 1 743 ? 228.620 212.545 161.275 1.00 62.37  ? 743 ALA B C   1 
ATOM   12003 O  O   . ALA B 1 743 ? 227.782 212.253 160.414 1.00 62.37  ? 743 ALA B O   1 
ATOM   12004 C  CB  . ALA B 1 743 ? 230.581 211.089 161.859 1.00 62.37  ? 743 ALA B CB  1 
ATOM   12005 N  N   . LEU B 1 744 ? 228.271 213.100 162.438 1.00 60.85  ? 744 LEU B N   1 
ATOM   12006 C  CA  . LEU B 1 744 ? 226.862 213.355 162.698 1.00 60.85  ? 744 LEU B CA  1 
ATOM   12007 C  C   . LEU B 1 744 ? 226.333 214.489 161.840 1.00 60.85  ? 744 LEU B C   1 
ATOM   12008 O  O   . LEU B 1 744 ? 225.140 214.511 161.540 1.00 60.85  ? 744 LEU B O   1 
ATOM   12009 C  CB  . LEU B 1 744 ? 226.614 213.641 164.182 1.00 60.85  ? 744 LEU B CB  1 
ATOM   12010 C  CG  . LEU B 1 744 ? 227.199 214.857 164.896 1.00 60.85  ? 744 LEU B CG  1 
ATOM   12011 C  CD1 . LEU B 1 744 ? 226.269 216.053 164.797 1.00 60.85  ? 744 LEU B CD1 1 
ATOM   12012 C  CD2 . LEU B 1 744 ? 227.479 214.520 166.348 1.00 60.85  ? 744 LEU B CD2 1 
ATOM   12013 N  N   . LEU B 1 745 ? 227.193 215.419 161.424 1.00 59.28  ? 745 LEU B N   1 
ATOM   12014 C  CA  . LEU B 1 745 ? 226.774 216.409 160.437 1.00 59.28  ? 745 LEU B CA  1 
ATOM   12015 C  C   . LEU B 1 745 ? 226.395 215.738 159.125 1.00 59.28  ? 745 LEU B C   1 
ATOM   12016 O  O   . LEU B 1 745 ? 225.381 216.080 158.505 1.00 59.28  ? 745 LEU B O   1 
ATOM   12017 C  CB  . LEU B 1 745 ? 227.881 217.440 160.219 1.00 59.28  ? 745 LEU B CB  1 
ATOM   12018 C  CG  . LEU B 1 745 ? 227.835 218.731 161.037 1.00 59.28  ? 745 LEU B CG  1 
ATOM   12019 C  CD1 . LEU B 1 745 ? 226.643 219.561 160.611 1.00 59.28  ? 745 LEU B CD1 1 
ATOM   12020 C  CD2 . LEU B 1 745 ? 227.761 218.453 162.517 1.00 59.28  ? 745 LEU B CD2 1 
ATOM   12021 N  N   . GLU B 1 746 ? 227.201 214.769 158.690 1.00 59.94  ? 746 GLU B N   1 
ATOM   12022 C  CA  . GLU B 1 746 ? 226.872 214.029 157.476 1.00 59.94  ? 746 GLU B CA  1 
ATOM   12023 C  C   . GLU B 1 746 ? 225.566 213.267 157.643 1.00 59.94  ? 746 GLU B C   1 
ATOM   12024 O  O   . GLU B 1 746 ? 224.734 213.230 156.729 1.00 59.94  ? 746 GLU B O   1 
ATOM   12025 C  CB  . GLU B 1 746 ? 228.008 213.075 157.116 1.00 59.94  ? 746 GLU B CB  1 
ATOM   12026 C  CG  . GLU B 1 746 ? 227.811 212.331 155.802 1.00 59.94  ? 746 GLU B CG  1 
ATOM   12027 C  CD  . GLU B 1 746 ? 227.615 213.262 154.619 1.00 59.94  ? 746 GLU B CD  1 
ATOM   12028 O  OE1 . GLU B 1 746 ? 226.470 213.705 154.383 1.00 59.94  ? 746 GLU B OE1 1 
ATOM   12029 O  OE2 . GLU B 1 746 ? 228.610 213.553 153.922 1.00 59.94  ? 746 GLU B OE2 1 
ATOM   12030 N  N   . ALA B 1 747 ? 225.372 212.660 158.812 1.00 57.66  ? 747 ALA B N   1 
ATOM   12031 C  CA  . ALA B 1 747 ? 224.133 211.938 159.076 1.00 57.66  ? 747 ALA B CA  1 
ATOM   12032 C  C   . ALA B 1 747 ? 222.935 212.874 159.039 1.00 57.66  ? 747 ALA B C   1 
ATOM   12033 O  O   . ALA B 1 747 ? 221.888 212.529 158.484 1.00 57.66  ? 747 ALA B O   1 
ATOM   12034 C  CB  . ALA B 1 747 ? 224.216 211.228 160.426 1.00 57.66  ? 747 ALA B CB  1 
ATOM   12035 N  N   . ILE B 1 748 ? 223.069 214.061 159.629 1.00 57.93  ? 748 ILE B N   1 
ATOM   12036 C  CA  . ILE B 1 748 ? 221.975 215.026 159.638 1.00 57.93  ? 748 ILE B CA  1 
ATOM   12037 C  C   . ILE B 1 748 ? 221.657 215.484 158.223 1.00 57.93  ? 748 ILE B C   1 
ATOM   12038 O  O   . ILE B 1 748 ? 220.485 215.583 157.831 1.00 57.93  ? 748 ILE B O   1 
ATOM   12039 C  CB  . ILE B 1 748 ? 222.321 216.210 160.553 1.00 57.93  ? 748 ILE B CB  1 
ATOM   12040 C  CG1 . ILE B 1 748 ? 222.289 215.763 162.006 1.00 57.93  ? 748 ILE B CG1 1 
ATOM   12041 C  CG2 . ILE B 1 748 ? 221.350 217.353 160.339 1.00 57.93  ? 748 ILE B CG2 1 
ATOM   12042 C  CD1 . ILE B 1 748 ? 220.949 215.214 162.425 1.00 57.93  ? 748 ILE B CD1 1 
ATOM   12043 N  N   . THR B 1 749 ? 222.691 215.764 157.432 1.00 56.73  ? 749 THR B N   1 
ATOM   12044 C  CA  . THR B 1 749 ? 222.458 216.181 156.057 1.00 56.73  ? 749 THR B CA  1 
ATOM   12045 C  C   . THR B 1 749 ? 221.758 215.088 155.267 1.00 56.73  ? 749 THR B C   1 
ATOM   12046 O  O   . THR B 1 749 ? 220.820 215.361 154.508 1.00 56.73  ? 749 THR B O   1 
ATOM   12047 C  CB  . THR B 1 749 ? 223.779 216.549 155.397 1.00 56.73  ? 749 THR B CB  1 
ATOM   12048 O  OG1 . THR B 1 749 ? 224.738 215.524 155.673 1.00 56.73  ? 749 THR B OG1 1 
ATOM   12049 C  CG2 . THR B 1 749 ? 224.285 217.876 155.938 1.00 56.73  ? 749 THR B CG2 1 
ATOM   12050 N  N   . SER B 1 750 ? 222.197 213.838 155.440 1.00 58.96  ? 750 SER B N   1 
ATOM   12051 C  CA  . SER B 1 750 ? 221.579 212.725 154.728 1.00 58.96  ? 750 SER B CA  1 
ATOM   12052 C  C   . SER B 1 750 ? 220.134 212.527 155.160 1.00 58.96  ? 750 SER B C   1 
ATOM   12053 O  O   . SER B 1 750 ? 219.272 212.224 154.332 1.00 58.96  ? 750 SER B O   1 
ATOM   12054 C  CB  . SER B 1 750 ? 222.385 211.447 154.951 1.00 58.96  ? 750 SER B CB  1 
ATOM   12055 O  OG  . SER B 1 750 ? 222.579 211.204 156.333 1.00 58.96  ? 750 SER B OG  1 
ATOM   12056 N  N   . ILE B 1 751 ? 219.852 212.679 156.455 1.00 55.16  ? 751 ILE B N   1 
ATOM   12057 C  CA  . ILE B 1 751 ? 218.479 212.551 156.931 1.00 55.16  ? 751 ILE B CA  1 
ATOM   12058 C  C   . ILE B 1 751 ? 217.607 213.623 156.307 1.00 55.16  ? 751 ILE B C   1 
ATOM   12059 O  O   . ILE B 1 751 ? 216.481 213.354 155.875 1.00 55.16  ? 751 ILE B O   1 
ATOM   12060 C  CB  . ILE B 1 751 ? 218.430 212.607 158.467 1.00 55.16  ? 751 ILE B CB  1 
ATOM   12061 C  CG1 . ILE B 1 751 ? 218.696 211.224 159.057 1.00 55.16  ? 751 ILE B CG1 1 
ATOM   12062 C  CG2 . ILE B 1 751 ? 217.086 213.116 158.943 1.00 55.16  ? 751 ILE B CG2 1 
ATOM   12063 C  CD1 . ILE B 1 751 ? 218.915 211.235 160.551 1.00 55.16  ? 751 ILE B CD1 1 
ATOM   12064 N  N   . GLY B 1 752 ? 218.109 214.855 156.249 1.00 59.45  ? 752 GLY B N   1 
ATOM   12065 C  CA  . GLY B 1 752 ? 217.348 215.910 155.602 1.00 59.45  ? 752 GLY B CA  1 
ATOM   12066 C  C   . GLY B 1 752 ? 217.085 215.606 154.140 1.00 59.45  ? 752 GLY B C   1 
ATOM   12067 O  O   . GLY B 1 752 ? 215.953 215.718 153.659 1.00 59.45  ? 752 GLY B O   1 
ATOM   12068 N  N   . GLN B 1 753 ? 218.127 215.181 153.424 1.00 62.41  ? 753 GLN B N   1 
ATOM   12069 C  CA  . GLN B 1 753 ? 217.980 214.879 152.005 1.00 62.41  ? 753 GLN B CA  1 
ATOM   12070 C  C   . GLN B 1 753 ? 216.978 213.755 151.788 1.00 62.41  ? 753 GLN B C   1 
ATOM   12071 O  O   . GLN B 1 753 ? 216.156 213.807 150.867 1.00 62.41  ? 753 GLN B O   1 
ATOM   12072 C  CB  . GLN B 1 753 ? 219.336 214.515 151.404 1.00 62.41  ? 753 GLN B CB  1 
ATOM   12073 C  CG  . GLN B 1 753 ? 220.307 215.680 151.314 1.00 62.41  ? 753 GLN B CG  1 
ATOM   12074 C  CD  . GLN B 1 753 ? 219.819 216.775 150.385 1.00 62.41  ? 753 GLN B CD  1 
ATOM   12075 O  OE1 . GLN B 1 753 ? 219.437 217.858 150.830 1.00 62.41  ? 753 GLN B OE1 1 
ATOM   12076 N  NE2 . GLN B 1 753 ? 219.829 216.498 149.087 1.00 62.41  ? 753 GLN B NE2 1 
ATOM   12077 N  N   . SER B 1 754 ? 217.028 212.730 152.636 1.00 61.16  ? 754 SER B N   1 
ATOM   12078 C  CA  . SER B 1 754 ? 216.125 211.598 152.487 1.00 61.16  ? 754 SER B CA  1 
ATOM   12079 C  C   . SER B 1 754 ? 214.691 211.996 152.794 1.00 61.16  ? 754 SER B C   1 
ATOM   12080 O  O   . SER B 1 754 ? 213.775 211.705 152.017 1.00 61.16  ? 754 SER B O   1 
ATOM   12081 C  CB  . SER B 1 754 ? 216.569 210.459 153.399 1.00 61.16  ? 754 SER B CB  1 
ATOM   12082 O  OG  . SER B 1 754 ? 216.540 210.859 154.757 1.00 61.16  ? 754 SER B OG  1 
ATOM   12083 N  N   . LEU B 1 755 ? 214.477 212.676 153.918 1.00 55.44  ? 755 LEU B N   1 
ATOM   12084 C  CA  . LEU B 1 755 ? 213.122 213.008 154.325 1.00 55.44  ? 755 LEU B CA  1 
ATOM   12085 C  C   . LEU B 1 755 ? 212.537 214.124 153.481 1.00 55.44  ? 755 LEU B C   1 
ATOM   12086 O  O   . LEU B 1 755 ? 211.337 214.389 153.587 1.00 55.44  ? 755 LEU B O   1 
ATOM   12087 C  CB  . LEU B 1 755 ? 213.100 213.398 155.801 1.00 55.44  ? 755 LEU B CB  1 
ATOM   12088 C  CG  . LEU B 1 755 ? 212.866 212.276 156.813 1.00 55.44  ? 755 LEU B CG  1 
ATOM   12089 C  CD1 . LEU B 1 755 ? 213.941 211.219 156.709 1.00 55.44  ? 755 LEU B CD1 1 
ATOM   12090 C  CD2 . LEU B 1 755 ? 212.802 212.824 158.224 1.00 55.44  ? 755 LEU B CD2 1 
ATOM   12091 N  N   . ASN B 1 756 ? 213.362 214.764 152.647 1.00 56.27  ? 756 ASN B N   1 
ATOM   12092 C  CA  . ASN B 1 756 ? 213.095 215.946 151.815 1.00 56.27  ? 756 ASN B CA  1 
ATOM   12093 C  C   . ASN B 1 756 ? 213.056 217.205 152.673 1.00 56.27  ? 756 ASN B C   1 
ATOM   12094 O  O   . ASN B 1 756 ? 212.725 218.285 152.162 1.00 56.27  ? 756 ASN B O   1 
ATOM   12095 C  CB  . ASN B 1 756 ? 211.844 215.811 150.924 1.00 56.27  ? 756 ASN B CB  1 
ATOM   12096 C  CG  . ASN B 1 756 ? 210.511 216.143 151.624 1.00 56.27  ? 756 ASN B CG  1 
ATOM   12097 O  OD1 . ASN B 1 756 ? 210.452 216.737 152.699 1.00 56.27  ? 756 ASN B OD1 1 
ATOM   12098 N  ND2 . ASN B 1 756 ? 209.423 215.741 150.981 1.00 56.27  ? 756 ASN B ND2 1 
ATOM   12099 N  N   . LEU B 1 757 ? 213.386 217.101 153.956 1.00 49.77  ? 757 LEU B N   1 
ATOM   12100 C  CA  . LEU B 1 757 ? 213.555 218.278 154.793 1.00 49.77  ? 757 LEU B CA  1 
ATOM   12101 C  C   . LEU B 1 757 ? 214.724 219.116 154.300 1.00 49.77  ? 757 LEU B C   1 
ATOM   12102 O  O   . LEU B 1 757 ? 215.695 218.599 153.744 1.00 49.77  ? 757 LEU B O   1 
ATOM   12103 C  CB  . LEU B 1 757 ? 213.807 217.872 156.241 1.00 49.77  ? 757 LEU B CB  1 
ATOM   12104 C  CG  . LEU B 1 757 ? 212.644 217.365 157.077 1.00 49.77  ? 757 LEU B CG  1 
ATOM   12105 C  CD1 . LEU B 1 757 ? 213.139 216.382 158.107 1.00 49.77  ? 757 LEU B CD1 1 
ATOM   12106 C  CD2 . LEU B 1 757 ? 212.002 218.540 157.756 1.00 49.77  ? 757 LEU B CD2 1 
ATOM   12107 N  N   . THR B 1 758 ? 214.625 220.423 154.498 1.00 41.76  ? 758 THR B N   1 
ATOM   12108 C  CA  . THR B 1 758 ? 215.749 221.291 154.211 1.00 41.76  ? 758 THR B CA  1 
ATOM   12109 C  C   . THR B 1 758 ? 216.609 221.440 155.452 1.00 41.76  ? 758 THR B C   1 
ATOM   12110 O  O   . THR B 1 758 ? 216.136 221.333 156.586 1.00 41.76  ? 758 THR B O   1 
ATOM   12111 C  CB  . THR B 1 758 ? 215.274 222.658 153.741 1.00 41.76  ? 758 THR B CB  1 
ATOM   12112 O  OG1 . THR B 1 758 ? 214.854 223.426 154.874 1.00 41.76  ? 758 THR B OG1 1 
ATOM   12113 C  CG2 . THR B 1 758 ? 214.110 222.503 152.789 1.00 41.76  ? 758 THR B CG2 1 
ATOM   12114 N  N   . VAL B 1 759 ? 217.892 221.676 155.226 1.00 36.57  ? 759 VAL B N   1 
ATOM   12115 C  CA  . VAL B 1 759 ? 218.854 221.797 156.305 1.00 36.57  ? 759 VAL B CA  1 
ATOM   12116 C  C   . VAL B 1 759 ? 219.530 223.149 156.199 1.00 36.57  ? 759 VAL B C   1 
ATOM   12117 O  O   . VAL B 1 759 ? 220.124 223.471 155.163 1.00 36.57  ? 759 VAL B O   1 
ATOM   12118 C  CB  . VAL B 1 759 ? 219.896 220.670 156.269 1.00 36.57  ? 759 VAL B CB  1 
ATOM   12119 C  CG1 . VAL B 1 759 ? 221.044 221.020 157.164 1.00 36.57  ? 759 VAL B CG1 1 
ATOM   12120 C  CG2 . VAL B 1 759 ? 219.271 219.366 156.709 1.00 36.57  ? 759 VAL B CG2 1 
ATOM   12121 N  N   . VAL B 1 760 ? 219.442 223.934 157.265 1.00 35.36  ? 760 VAL B N   1 
ATOM   12122 C  CA  . VAL B 1 760 ? 220.138 225.204 157.355 1.00 35.36  ? 760 VAL B CA  1 
ATOM   12123 C  C   . VAL B 1 760 ? 221.176 225.086 158.458 1.00 35.36  ? 760 VAL B C   1 
ATOM   12124 O  O   . VAL B 1 760 ? 221.019 224.317 159.411 1.00 35.36  ? 760 VAL B O   1 
ATOM   12125 C  CB  . VAL B 1 760 ? 219.175 226.379 157.622 1.00 35.36  ? 760 VAL B CB  1 
ATOM   12126 C  CG1 . VAL B 1 760 ? 218.019 226.341 156.652 1.00 35.36  ? 760 VAL B CG1 1 
ATOM   12127 C  CG2 . VAL B 1 760 ? 218.667 226.342 159.044 1.00 35.36  ? 760 VAL B CG2 1 
ATOM   12128 N  N   . ALA B 1 761 ? 222.260 225.827 158.298 1.00 36.35  ? 761 ALA B N   1 
ATOM   12129 C  CA  . ALA B 1 761 ? 223.364 225.822 159.240 1.00 36.35  ? 761 ALA B CA  1 
ATOM   12130 C  C   . ALA B 1 761 ? 223.496 227.200 159.860 1.00 36.35  ? 761 ALA B C   1 
ATOM   12131 O  O   . ALA B 1 761 ? 223.354 228.214 159.167 1.00 36.35  ? 761 ALA B O   1 
ATOM   12132 C  CB  . ALA B 1 761 ? 224.671 225.427 158.556 1.00 36.35  ? 761 ALA B CB  1 
ATOM   12133 N  N   . GLU B 1 762 ? 223.755 227.242 161.162 1.00 43.81  ? 762 GLU B N   1 
ATOM   12134 C  CA  . GLU B 1 762 ? 223.840 228.497 161.893 1.00 43.81  ? 762 GLU B CA  1 
ATOM   12135 C  C   . GLU B 1 762 ? 225.230 228.654 162.489 1.00 43.81  ? 762 GLU B C   1 
ATOM   12136 O  O   . GLU B 1 762 ? 225.801 227.688 163.001 1.00 43.81  ? 762 GLU B O   1 
ATOM   12137 C  CB  . GLU B 1 762 ? 222.784 228.557 162.998 1.00 43.81  ? 762 GLU B CB  1 
ATOM   12138 C  CG  . GLU B 1 762 ? 222.786 229.854 163.794 1.00 43.81  ? 762 GLU B CG  1 
ATOM   12139 C  CD  . GLU B 1 762 ? 221.739 229.868 164.891 1.00 43.81  ? 762 GLU B CD  1 
ATOM   12140 O  OE1 . GLU B 1 762 ? 221.022 228.856 165.044 1.00 43.81  ? 762 GLU B OE1 1 
ATOM   12141 O  OE2 . GLU B 1 762 ? 221.634 230.890 165.601 1.00 43.81  ? 762 GLU B OE2 1 
ATOM   12142 N  N   . GLY B 1 763 ? 225.767 229.868 162.416 1.00 48.19  ? 763 GLY B N   1 
ATOM   12143 C  CA  . GLY B 1 763 ? 227.023 230.180 163.062 1.00 48.19  ? 763 GLY B CA  1 
ATOM   12144 C  C   . GLY B 1 763 ? 228.271 229.809 162.300 1.00 48.19  ? 763 GLY B C   1 
ATOM   12145 O  O   . GLY B 1 763 ? 229.269 229.429 162.923 1.00 48.19  ? 763 GLY B O   1 
ATOM   12146 N  N   . VAL B 1 764 ? 228.258 229.902 160.976 1.00 47.06  ? 764 VAL B N   1 
ATOM   12147 C  CA  . VAL B 1 764 ? 229.450 229.659 160.173 1.00 47.06  ? 764 VAL B CA  1 
ATOM   12148 C  C   . VAL B 1 764 ? 230.203 230.974 160.035 1.00 47.06  ? 764 VAL B C   1 
ATOM   12149 O  O   . VAL B 1 764 ? 229.592 232.048 159.994 1.00 47.06  ? 764 VAL B O   1 
ATOM   12150 C  CB  . VAL B 1 764 ? 229.082 229.083 158.797 1.00 47.06  ? 764 VAL B CB  1 
ATOM   12151 C  CG1 . VAL B 1 764 ? 228.455 230.146 157.938 1.00 47.06  ? 764 VAL B CG1 1 
ATOM   12152 C  CG2 . VAL B 1 764 ? 230.300 228.504 158.117 1.00 47.06  ? 764 VAL B CG2 1 
ATOM   12153 N  N   . GLU B 1 765 ? 231.526 230.903 160.010 1.00 51.81  ? 765 GLU B N   1 
ATOM   12154 C  CA  . GLU B 1 765 ? 232.325 232.110 159.838 1.00 51.81  ? 765 GLU B CA  1 
ATOM   12155 C  C   . GLU B 1 765 ? 233.391 232.001 158.760 1.00 51.81  ? 765 GLU B C   1 
ATOM   12156 O  O   . GLU B 1 765 ? 233.635 232.977 158.048 1.00 51.81  ? 765 GLU B O   1 
ATOM   12157 C  CB  . GLU B 1 765 ? 232.993 232.496 161.162 1.00 51.81  ? 765 GLU B CB  1 
ATOM   12158 C  CG  . GLU B 1 765 ? 232.022 232.752 162.286 1.00 51.81  ? 765 GLU B CG  1 
ATOM   12159 C  CD  . GLU B 1 765 ? 231.731 231.503 163.082 1.00 51.81  ? 765 GLU B CD  1 
ATOM   12160 O  OE1 . GLU B 1 765 ? 232.336 230.455 162.777 1.00 51.81  ? 765 GLU B OE1 1 
ATOM   12161 O  OE2 . GLU B 1 765 ? 230.899 231.564 164.011 1.00 51.81  ? 765 GLU B OE2 1 
ATOM   12162 N  N   . THR B 1 766 ? 234.031 230.845 158.610 1.00 58.39  ? 766 THR B N   1 
ATOM   12163 C  CA  . THR B 1 766 ? 235.247 230.736 157.818 1.00 58.39  ? 766 THR B CA  1 
ATOM   12164 C  C   . THR B 1 766 ? 235.009 229.960 156.530 1.00 58.39  ? 766 THR B C   1 
ATOM   12165 O  O   . THR B 1 766 ? 234.081 229.152 156.423 1.00 58.39  ? 766 THR B O   1 
ATOM   12166 C  CB  . THR B 1 766 ? 236.361 230.061 158.616 1.00 58.39  ? 766 THR B CB  1 
ATOM   12167 O  OG1 . THR B 1 766 ? 236.021 228.690 158.837 1.00 58.39  ? 766 THR B OG1 1 
ATOM   12168 C  CG2 . THR B 1 766 ? 236.546 230.752 159.957 1.00 58.39  ? 766 THR B CG2 1 
ATOM   12169 N  N   . LYS B 1 767 ? 235.877 230.219 155.549 1.00 61.39  ? 767 LYS B N   1 
ATOM   12170 C  CA  . LYS B 1 767 ? 235.742 229.585 154.244 1.00 61.39  ? 767 LYS B CA  1 
ATOM   12171 C  C   . LYS B 1 767 ? 235.980 228.085 154.318 1.00 61.39  ? 767 LYS B C   1 
ATOM   12172 O  O   . LYS B 1 767 ? 235.358 227.325 153.570 1.00 61.39  ? 767 LYS B O   1 
ATOM   12173 C  CB  . LYS B 1 767 ? 236.698 230.234 153.242 1.00 61.39  ? 767 LYS B CB  1 
ATOM   12174 C  CG  . LYS B 1 767 ? 238.173 230.064 153.572 1.00 61.39  ? 767 LYS B CG  1 
ATOM   12175 C  CD  . LYS B 1 767 ? 239.030 231.058 152.805 1.00 61.39  ? 767 LYS B CD  1 
ATOM   12176 C  CE  . LYS B 1 767 ? 238.946 230.819 151.306 1.00 61.39  ? 767 LYS B CE  1 
ATOM   12177 N  NZ  . LYS B 1 767 ? 239.682 229.590 150.899 1.00 61.39  ? 767 LYS B NZ  1 
ATOM   12178 N  N   . GLU B 1 768 ? 236.871 227.636 155.203 1.00 61.88  ? 768 GLU B N   1 
ATOM   12179 C  CA  . GLU B 1 768 ? 237.034 226.200 155.390 1.00 61.88  ? 768 GLU B CA  1 
ATOM   12180 C  C   . GLU B 1 768 ? 235.749 225.575 155.915 1.00 61.88  ? 768 GLU B C   1 
ATOM   12181 O  O   . GLU B 1 768 ? 235.334 224.507 155.449 1.00 61.88  ? 768 GLU B O   1 
ATOM   12182 C  CB  . GLU B 1 768 ? 238.209 225.913 156.326 1.00 61.88  ? 768 GLU B CB  1 
ATOM   12183 C  CG  . GLU B 1 768 ? 238.169 226.648 157.654 1.00 61.88  ? 768 GLU B CG  1 
ATOM   12184 C  CD  . GLU B 1 768 ? 238.965 227.938 157.630 1.00 61.88  ? 768 GLU B CD  1 
ATOM   12185 O  OE1 . GLU B 1 768 ? 239.250 228.442 156.524 1.00 61.88  ? 768 GLU B OE1 1 
ATOM   12186 O  OE2 . GLU B 1 768 ? 239.308 228.447 158.718 1.00 61.88  ? 768 GLU B OE2 1 
ATOM   12187 N  N   . GLN B 1 769 ? 235.094 226.236 156.873 1.00 61.12  ? 769 GLN B N   1 
ATOM   12188 C  CA  . GLN B 1 769 ? 233.824 225.727 157.375 1.00 61.12  ? 769 GLN B CA  1 
ATOM   12189 C  C   . GLN B 1 769 ? 232.773 225.700 156.276 1.00 61.12  ? 769 GLN B C   1 
ATOM   12190 O  O   . GLN B 1 769 ? 232.004 224.736 156.167 1.00 61.12  ? 769 GLN B O   1 
ATOM   12191 C  CB  . GLN B 1 769 ? 233.343 226.568 158.554 1.00 61.12  ? 769 GLN B CB  1 
ATOM   12192 C  CG  . GLN B 1 769 ? 234.184 226.419 159.801 1.00 61.12  ? 769 GLN B CG  1 
ATOM   12193 C  CD  . GLN B 1 769 ? 233.563 225.479 160.810 1.00 61.12  ? 769 GLN B CD  1 
ATOM   12194 O  OE1 . GLN B 1 769 ? 233.068 224.409 160.455 1.00 61.12  ? 769 GLN B OE1 1 
ATOM   12195 N  NE2 . GLN B 1 769 ? 233.585 225.873 162.078 1.00 61.12  ? 769 GLN B NE2 1 
ATOM   12196 N  N   . PHE B 1 770 ? 232.725 226.746 155.447 1.00 53.64  ? 770 PHE B N   1 
ATOM   12197 C  CA  . PHE B 1 770 ? 231.746 226.756 154.365 1.00 53.64  ? 770 PHE B CA  1 
ATOM   12198 C  C   . PHE B 1 770 ? 232.004 225.631 153.374 1.00 53.64  ? 770 PHE B C   1 
ATOM   12199 O  O   . PHE B 1 770 ? 231.064 224.985 152.903 1.00 53.64  ? 770 PHE B O   1 
ATOM   12200 C  CB  . PHE B 1 770 ? 231.746 228.089 153.631 1.00 53.64  ? 770 PHE B CB  1 
ATOM   12201 C  CG  . PHE B 1 770 ? 231.061 228.024 152.307 1.00 53.64  ? 770 PHE B CG  1 
ATOM   12202 C  CD1 . PHE B 1 770 ? 229.701 227.826 152.238 1.00 53.64  ? 770 PHE B CD1 1 
ATOM   12203 C  CD2 . PHE B 1 770 ? 231.775 228.125 151.135 1.00 53.64  ? 770 PHE B CD2 1 
ATOM   12204 C  CE1 . PHE B 1 770 ? 229.060 227.750 151.033 1.00 53.64  ? 770 PHE B CE1 1 
ATOM   12205 C  CE2 . PHE B 1 770 ? 231.134 228.050 149.920 1.00 53.64  ? 770 PHE B CE2 1 
ATOM   12206 C  CZ  . PHE B 1 770 ? 229.772 227.863 149.873 1.00 53.64  ? 770 PHE B CZ  1 
ATOM   12207 N  N   . GLU B 1 771 ? 233.272 225.393 153.030 1.00 59.00  ? 771 GLU B N   1 
ATOM   12208 C  CA  . GLU B 1 771 ? 233.592 224.319 152.095 1.00 59.00  ? 771 GLU B CA  1 
ATOM   12209 C  C   . GLU B 1 771 ? 233.241 222.959 152.678 1.00 59.00  ? 771 GLU B C   1 
ATOM   12210 O  O   . GLU B 1 771 ? 232.738 222.079 151.967 1.00 59.00  ? 771 GLU B O   1 
ATOM   12211 C  CB  . GLU B 1 771 ? 235.071 224.375 151.713 1.00 59.00  ? 771 GLU B CB  1 
ATOM   12212 C  CG  . GLU B 1 771 ? 235.424 225.513 150.769 1.00 59.00  ? 771 GLU B CG  1 
ATOM   12213 C  CD  . GLU B 1 771 ? 235.149 225.178 149.316 1.00 59.00  ? 771 GLU B CD  1 
ATOM   12214 O  OE1 . GLU B 1 771 ? 234.509 224.139 149.049 1.00 59.00  ? 771 GLU B OE1 1 
ATOM   12215 O  OE2 . GLU B 1 771 ? 235.575 225.957 148.437 1.00 59.00  ? 771 GLU B OE2 1 
ATOM   12216 N  N   . MET B 1 772 ? 233.505 222.762 153.971 1.00 59.31  ? 772 MET B N   1 
ATOM   12217 C  CA  . MET B 1 772 ? 233.127 221.508 154.608 1.00 59.31  ? 772 MET B CA  1 
ATOM   12218 C  C   . MET B 1 772 ? 231.618 221.312 154.565 1.00 59.31  ? 772 MET B C   1 
ATOM   12219 O  O   . MET B 1 772 ? 231.130 220.225 154.235 1.00 59.31  ? 772 MET B O   1 
ATOM   12220 C  CB  . MET B 1 772 ? 233.639 221.473 156.047 1.00 59.31  ? 772 MET B CB  1 
ATOM   12221 C  CG  . MET B 1 772 ? 235.149 221.469 156.156 1.00 59.31  ? 772 MET B CG  1 
ATOM   12222 S  SD  . MET B 1 772 ? 235.734 222.118 157.728 1.00 59.31  ? 772 MET B SD  1 
ATOM   12223 C  CE  . MET B 1 772 ? 235.742 220.615 158.694 1.00 59.31  ? 772 MET B CE  1 
ATOM   12224 N  N   . LEU B 1 773 ? 230.859 222.365 154.879 1.00 55.07  ? 773 LEU B N   1 
ATOM   12225 C  CA  . LEU B 1 773 ? 229.407 222.250 154.823 1.00 55.07  ? 773 LEU B CA  1 
ATOM   12226 C  C   . LEU B 1 773 ? 228.928 221.980 153.404 1.00 55.07  ? 773 LEU B C   1 
ATOM   12227 O  O   . LEU B 1 773 ? 227.992 221.197 153.199 1.00 55.07  ? 773 LEU B O   1 
ATOM   12228 C  CB  . LEU B 1 773 ? 228.759 223.510 155.387 1.00 55.07  ? 773 LEU B CB  1 
ATOM   12229 C  CG  . LEU B 1 773 ? 229.064 223.755 156.862 1.00 55.07  ? 773 LEU B CG  1 
ATOM   12230 C  CD1 . LEU B 1 773 ? 228.130 224.801 157.436 1.00 55.07  ? 773 LEU B CD1 1 
ATOM   12231 C  CD2 . LEU B 1 773 ? 228.978 222.463 157.652 1.00 55.07  ? 773 LEU B CD2 1 
ATOM   12232 N  N   . ARG B 1 774 ? 229.571 222.597 152.415 1.00 57.62  ? 774 ARG B N   1 
ATOM   12233 C  CA  . ARG B 1 774 ? 229.191 222.376 151.027 1.00 57.62  ? 774 ARG B CA  1 
ATOM   12234 C  C   . ARG B 1 774 ? 229.421 220.928 150.618 1.00 57.62  ? 774 ARG B C   1 
ATOM   12235 O  O   . ARG B 1 774 ? 228.577 220.318 149.951 1.00 57.62  ? 774 ARG B O   1 
ATOM   12236 C  CB  . ARG B 1 774 ? 229.976 223.317 150.118 1.00 57.62  ? 774 ARG B CB  1 
ATOM   12237 C  CG  . ARG B 1 774 ? 229.598 223.202 148.660 1.00 57.62  ? 774 ARG B CG  1 
ATOM   12238 C  CD  . ARG B 1 774 ? 228.124 223.503 148.478 1.00 57.62  ? 774 ARG B CD  1 
ATOM   12239 N  NE  . ARG B 1 774 ? 227.319 222.290 148.426 1.00 57.62  ? 774 ARG B NE  1 
ATOM   12240 C  CZ  . ARG B 1 774 ? 226.022 222.240 148.695 1.00 57.62  ? 774 ARG B CZ  1 
ATOM   12241 N  NH1 . ARG B 1 774 ? 225.350 223.319 149.061 1.00 57.62  ? 774 ARG B NH1 1 
ATOM   12242 N  NH2 . ARG B 1 774 ? 225.383 221.078 148.596 1.00 57.62  ? 774 ARG B NH2 1 
ATOM   12243 N  N   . LYS B 1 775 ? 230.564 220.357 151.008 1.00 60.09  ? 775 LYS B N   1 
ATOM   12244 C  CA  . LYS B 1 775 ? 230.847 218.976 150.627 1.00 60.09  ? 775 LYS B CA  1 
ATOM   12245 C  C   . LYS B 1 775 ? 229.938 218.006 151.370 1.00 60.09  ? 775 LYS B C   1 
ATOM   12246 O  O   . LYS B 1 775 ? 229.581 216.951 150.834 1.00 60.09  ? 775 LYS B O   1 
ATOM   12247 C  CB  . LYS B 1 775 ? 232.317 218.636 150.871 1.00 60.09  ? 775 LYS B CB  1 
ATOM   12248 C  CG  . LYS B 1 775 ? 232.699 218.440 152.321 1.00 60.09  ? 775 LYS B CG  1 
ATOM   12249 C  CD  . LYS B 1 775 ? 234.098 217.858 152.449 1.00 60.09  ? 775 LYS B CD  1 
ATOM   12250 C  CE  . LYS B 1 775 ? 235.116 218.700 151.696 1.00 60.09  ? 775 LYS B CE  1 
ATOM   12251 N  NZ  . LYS B 1 775 ? 235.286 220.045 152.310 1.00 60.09  ? 775 LYS B NZ  1 
ATOM   12252 N  N   . ILE B 1 776 ? 229.547 218.343 152.602 1.00 55.67  ? 776 ILE B N   1 
ATOM   12253 C  CA  . ILE B 1 776 ? 228.553 217.540 153.306 1.00 55.67  ? 776 ILE B CA  1 
ATOM   12254 C  C   . ILE B 1 776 ? 227.154 217.769 152.756 1.00 55.67  ? 776 ILE B C   1 
ATOM   12255 O  O   . ILE B 1 776 ? 226.232 217.015 153.084 1.00 55.67  ? 776 ILE B O   1 
ATOM   12256 C  CB  . ILE B 1 776 ? 228.630 217.833 154.819 1.00 55.67  ? 776 ILE B CB  1 
ATOM   12257 C  CG1 . ILE B 1 776 ? 230.052 217.616 155.327 1.00 55.67  ? 776 ILE B CG1 1 
ATOM   12258 C  CG2 . ILE B 1 776 ? 227.738 216.913 155.605 1.00 55.67  ? 776 ILE B CG2 1 
ATOM   12259 C  CD1 . ILE B 1 776 ? 230.323 218.266 156.663 1.00 55.67  ? 776 ILE B CD1 1 
ATOM   12260 N  N   . HIS B 1 777 ? 226.990 218.770 151.890 1.00 57.06  ? 777 HIS B N   1 
ATOM   12261 C  CA  . HIS B 1 777 ? 225.709 219.098 151.258 1.00 57.06  ? 777 HIS B CA  1 
ATOM   12262 C  C   . HIS B 1 777 ? 224.704 219.669 152.261 1.00 57.06  ? 777 HIS B C   1 
ATOM   12263 O  O   . HIS B 1 777 ? 223.591 219.166 152.413 1.00 57.06  ? 777 HIS B O   1 
ATOM   12264 C  CB  . HIS B 1 777 ? 225.126 217.894 150.519 1.00 57.06  ? 777 HIS B CB  1 
ATOM   12265 C  CG  . HIS B 1 777 ? 225.968 217.435 149.373 1.00 57.06  ? 777 HIS B CG  1 
ATOM   12266 N  ND1 . HIS B 1 777 ? 226.934 218.232 148.798 1.00 57.06  ? 777 HIS B ND1 1 
ATOM   12267 C  CD2 . HIS B 1 777 ? 225.986 216.268 148.688 1.00 57.06  ? 777 HIS B CD2 1 
ATOM   12268 C  CE1 . HIS B 1 777 ? 227.514 217.573 147.811 1.00 57.06  ? 777 HIS B CE1 1 
ATOM   12269 N  NE2 . HIS B 1 777 ? 226.957 216.379 147.723 1.00 57.06  ? 777 HIS B NE2 1 
ATOM   12270 N  N   . CYS B 1 778 ? 225.119 220.733 152.951 1.00 50.98  ? 778 CYS B N   1 
ATOM   12271 C  CA  . CYS B 1 778 ? 224.203 221.590 153.696 1.00 50.98  ? 778 CYS B CA  1 
ATOM   12272 C  C   . CYS B 1 778 ? 223.468 222.493 152.714 1.00 50.98  ? 778 CYS B C   1 
ATOM   12273 O  O   . CYS B 1 778 ? 224.102 223.213 151.937 1.00 50.98  ? 778 CYS B O   1 
ATOM   12274 C  CB  . CYS B 1 778 ? 224.967 222.423 154.718 1.00 50.98  ? 778 CYS B CB  1 
ATOM   12275 S  SG  . CYS B 1 778 ? 225.464 221.530 156.196 1.00 50.98  ? 778 CYS B SG  1 
ATOM   12276 N  N   . ARG B 1 779 ? 222.136 222.466 152.748 1.00 42.87  ? 779 ARG B N   1 
ATOM   12277 C  CA  . ARG B 1 779 ? 221.368 223.142 151.707 1.00 42.87  ? 779 ARG B CA  1 
ATOM   12278 C  C   . ARG B 1 779 ? 221.365 224.658 151.851 1.00 42.87  ? 779 ARG B C   1 
ATOM   12279 O  O   . ARG B 1 779 ? 221.493 225.362 150.845 1.00 42.87  ? 779 ARG B O   1 
ATOM   12280 C  CB  . ARG B 1 779 ? 219.935 222.624 151.686 1.00 42.87  ? 779 ARG B CB  1 
ATOM   12281 C  CG  . ARG B 1 779 ? 219.660 221.681 150.540 1.00 42.87  ? 779 ARG B CG  1 
ATOM   12282 C  CD  . ARG B 1 779 ? 219.449 222.435 149.250 1.00 42.87  ? 779 ARG B CD  1 
ATOM   12283 N  NE  . ARG B 1 779 ? 218.447 223.483 149.388 1.00 42.87  ? 779 ARG B NE  1 
ATOM   12284 C  CZ  . ARG B 1 779 ? 217.145 223.297 149.221 1.00 42.87  ? 779 ARG B CZ  1 
ATOM   12285 N  NH1 . ARG B 1 779 ? 216.652 222.110 148.911 1.00 42.87  ? 779 ARG B NH1 1 
ATOM   12286 N  NH2 . ARG B 1 779 ? 216.318 224.327 149.371 1.00 42.87  ? 779 ARG B NH2 1 
ATOM   12287 N  N   . VAL B 1 780 ? 221.210 225.187 153.065 1.00 42.00  ? 780 VAL B N   1 
ATOM   12288 C  CA  . VAL B 1 780 ? 221.156 226.630 153.278 1.00 42.00  ? 780 VAL B CA  1 
ATOM   12289 C  C   . VAL B 1 780 ? 222.070 226.981 154.445 1.00 42.00  ? 780 VAL B C   1 
ATOM   12290 O  O   . VAL B 1 780 ? 222.158 226.246 155.432 1.00 42.00  ? 780 VAL B O   1 
ATOM   12291 C  CB  . VAL B 1 780 ? 219.709 227.110 153.532 1.00 42.00  ? 780 VAL B CB  1 
ATOM   12292 C  CG1 . VAL B 1 780 ? 219.670 228.606 153.736 1.00 42.00  ? 780 VAL B CG1 1 
ATOM   12293 C  CG2 . VAL B 1 780 ? 218.804 226.705 152.390 1.00 42.00  ? 780 VAL B CG2 1 
ATOM   12294 N  N   . ILE B 1 781 ? 222.763 228.108 154.326 1.00 38.93  ? 781 ILE B N   1 
ATOM   12295 C  CA  . ILE B 1 781 ? 223.755 228.520 155.305 1.00 38.93  ? 781 ILE B CA  1 
ATOM   12296 C  C   . ILE B 1 781 ? 223.471 229.948 155.741 1.00 38.93  ? 781 ILE B C   1 
ATOM   12297 O  O   . ILE B 1 781 ? 223.101 230.800 154.927 1.00 38.93  ? 781 ILE B O   1 
ATOM   12298 C  CB  . ILE B 1 781 ? 225.172 228.400 154.731 1.00 38.93  ? 781 ILE B CB  1 
ATOM   12299 C  CG1 . ILE B 1 781 ? 225.422 226.972 154.275 1.00 38.93  ? 781 ILE B CG1 1 
ATOM   12300 C  CG2 . ILE B 1 781 ? 226.184 228.780 155.759 1.00 38.93  ? 781 ILE B CG2 1 
ATOM   12301 C  CD1 . ILE B 1 781 ? 226.777 226.759 153.672 1.00 38.93  ? 781 ILE B CD1 1 
ATOM   12302 N  N   . GLN B 1 782 ? 223.640 230.215 157.037 1.00 42.67  ? 782 GLN B N   1 
ATOM   12303 C  CA  . GLN B 1 782 ? 223.519 231.567 157.568 1.00 42.67  ? 782 GLN B CA  1 
ATOM   12304 C  C   . GLN B 1 782 ? 224.699 231.819 158.492 1.00 42.67  ? 782 GLN B C   1 
ATOM   12305 O  O   . GLN B 1 782 ? 225.386 230.890 158.921 1.00 42.67  ? 782 GLN B O   1 
ATOM   12306 C  CB  . GLN B 1 782 ? 222.186 231.760 158.297 1.00 42.67  ? 782 GLN B CB  1 
ATOM   12307 C  CG  . GLN B 1 782 ? 222.218 231.398 159.766 1.00 42.67  ? 782 GLN B CG  1 
ATOM   12308 C  CD  . GLN B 1 782 ? 220.901 231.682 160.461 1.00 42.67  ? 782 GLN B CD  1 
ATOM   12309 O  OE1 . GLN B 1 782 ? 219.852 231.748 159.825 1.00 42.67  ? 782 GLN B OE1 1 
ATOM   12310 N  NE2 . GLN B 1 782 ? 220.950 231.850 161.775 1.00 42.67  ? 782 GLN B NE2 1 
ATOM   12311 N  N   . GLY B 1 783 ? 224.942 233.078 158.796 1.00 47.10  ? 783 GLY B N   1 
ATOM   12312 C  CA  . GLY B 1 783 ? 225.989 233.422 159.732 1.00 47.10  ? 783 GLY B CA  1 
ATOM   12313 C  C   . GLY B 1 783 ? 226.808 234.617 159.292 1.00 47.10  ? 783 GLY B C   1 
ATOM   12314 O  O   . GLY B 1 783 ? 226.457 235.371 158.380 1.00 47.10  ? 783 GLY B O   1 
ATOM   12315 N  N   . TYR B 1 784 ? 227.943 234.776 159.972 1.00 51.35  ? 784 TYR B N   1 
ATOM   12316 C  CA  . TYR B 1 784 ? 228.782 235.943 159.747 1.00 51.35  ? 784 TYR B CA  1 
ATOM   12317 C  C   . TYR B 1 784 ? 229.530 235.860 158.427 1.00 51.35  ? 784 TYR B C   1 
ATOM   12318 O  O   . TYR B 1 784 ? 229.971 236.890 157.907 1.00 51.35  ? 784 TYR B O   1 
ATOM   12319 C  CB  . TYR B 1 784 ? 229.768 236.106 160.900 1.00 51.35  ? 784 TYR B CB  1 
ATOM   12320 C  CG  . TYR B 1 784 ? 229.123 236.492 162.210 1.00 51.35  ? 784 TYR B CG  1 
ATOM   12321 C  CD1 . TYR B 1 784 ? 228.789 237.812 162.478 1.00 51.35  ? 784 TYR B CD1 1 
ATOM   12322 C  CD2 . TYR B 1 784 ? 228.850 235.537 163.179 1.00 51.35  ? 784 TYR B CD2 1 
ATOM   12323 C  CE1 . TYR B 1 784 ? 228.199 238.171 163.675 1.00 51.35  ? 784 TYR B CE1 1 
ATOM   12324 C  CE2 . TYR B 1 784 ? 228.259 235.885 164.380 1.00 51.35  ? 784 TYR B CE2 1 
ATOM   12325 C  CZ  . TYR B 1 784 ? 227.936 237.204 164.622 1.00 51.35  ? 784 TYR B CZ  1 
ATOM   12326 O  OH  . TYR B 1 784 ? 227.349 237.557 165.816 1.00 51.35  ? 784 TYR B OH  1 
ATOM   12327 N  N   . PHE B 1 785 ? 229.699 234.659 157.875 1.00 48.43  ? 785 PHE B N   1 
ATOM   12328 C  CA  . PHE B 1 785 ? 230.453 234.527 156.635 1.00 48.43  ? 785 PHE B CA  1 
ATOM   12329 C  C   . PHE B 1 785 ? 229.777 235.285 155.507 1.00 48.43  ? 785 PHE B C   1 
ATOM   12330 O  O   . PHE B 1 785 ? 230.431 235.996 154.737 1.00 48.43  ? 785 PHE B O   1 
ATOM   12331 C  CB  . PHE B 1 785 ? 230.616 233.057 156.260 1.00 48.43  ? 785 PHE B CB  1 
ATOM   12332 C  CG  . PHE B 1 785 ? 231.411 232.842 155.006 1.00 48.43  ? 785 PHE B CG  1 
ATOM   12333 C  CD1 . PHE B 1 785 ? 232.720 233.274 154.920 1.00 48.43  ? 785 PHE B CD1 1 
ATOM   12334 C  CD2 . PHE B 1 785 ? 230.848 232.219 153.909 1.00 48.43  ? 785 PHE B CD2 1 
ATOM   12335 C  CE1 . PHE B 1 785 ? 233.453 233.082 153.766 1.00 48.43  ? 785 PHE B CE1 1 
ATOM   12336 C  CE2 . PHE B 1 785 ? 231.578 232.027 152.754 1.00 48.43  ? 785 PHE B CE2 1 
ATOM   12337 C  CZ  . PHE B 1 785 ? 232.881 232.460 152.684 1.00 48.43  ? 785 PHE B CZ  1 
ATOM   12338 N  N   . PHE B 1 786 ? 228.459 235.152 155.399 1.00 43.33  ? 786 PHE B N   1 
ATOM   12339 C  CA  . PHE B 1 786 ? 227.739 235.828 154.329 1.00 43.33  ? 786 PHE B CA  1 
ATOM   12340 C  C   . PHE B 1 786 ? 227.416 237.268 154.696 1.00 43.33  ? 786 PHE B C   1 
ATOM   12341 O  O   . PHE B 1 786 ? 227.898 238.207 154.057 1.00 43.33  ? 786 PHE B O   1 
ATOM   12342 C  CB  . PHE B 1 786 ? 226.460 235.066 154.002 1.00 43.33  ? 786 PHE B CB  1 
ATOM   12343 C  CG  . PHE B 1 786 ? 226.666 233.961 153.043 1.00 43.33  ? 786 PHE B CG  1 
ATOM   12344 C  CD1 . PHE B 1 786 ? 227.935 233.633 152.631 1.00 43.33  ? 786 PHE B CD1 1 
ATOM   12345 C  CD2 . PHE B 1 786 ? 225.598 233.258 152.537 1.00 43.33  ? 786 PHE B CD2 1 
ATOM   12346 C  CE1 . PHE B 1 786 ? 228.140 232.623 151.740 1.00 43.33  ? 786 PHE B CE1 1 
ATOM   12347 C  CE2 . PHE B 1 786 ? 225.796 232.246 151.646 1.00 43.33  ? 786 PHE B CE2 1 
ATOM   12348 C  CZ  . PHE B 1 786 ? 227.070 231.925 151.244 1.00 43.33  ? 786 PHE B CZ  1 
ATOM   12349 N  N   . SER B 1 787 ? 226.602 237.458 155.730 1.00 47.14  ? 787 SER B N   1 
ATOM   12350 C  CA  . SER B 1 787 ? 226.212 238.796 156.148 1.00 47.14  ? 787 SER B CA  1 
ATOM   12351 C  C   . SER B 1 787 ? 225.694 238.737 157.574 1.00 47.14  ? 787 SER B C   1 
ATOM   12352 O  O   . SER B 1 787 ? 224.849 237.900 157.895 1.00 47.14  ? 787 SER B O   1 
ATOM   12353 C  CB  . SER B 1 787 ? 225.145 239.377 155.219 1.00 47.14  ? 787 SER B CB  1 
ATOM   12354 O  OG  . SER B 1 787 ? 224.693 240.633 155.693 1.00 47.14  ? 787 SER B OG  1 
ATOM   12355 N  N   . ARG B 1 788 ? 226.187 239.639 158.408 1.00 49.50  ? 788 ARG B N   1 
ATOM   12356 C  CA  . ARG B 1 788 ? 225.800 239.737 159.805 1.00 49.50  ? 788 ARG B CA  1 
ATOM   12357 C  C   . ARG B 1 788 ? 224.341 240.162 159.869 1.00 49.50  ? 788 ARG B C   1 
ATOM   12358 O  O   . ARG B 1 788 ? 223.803 240.642 158.865 1.00 49.50  ? 788 ARG B O   1 
ATOM   12359 C  CB  . ARG B 1 788 ? 226.701 240.737 160.533 1.00 49.50  ? 788 ARG B CB  1 
ATOM   12360 C  CG  . ARG B 1 788 ? 226.413 242.187 160.185 1.00 49.50  ? 788 ARG B CG  1 
ATOM   12361 C  CD  . ARG B 1 788 ? 227.354 243.134 160.914 1.00 49.50  ? 788 ARG B CD  1 
ATOM   12362 N  NE  . ARG B 1 788 ? 228.718 243.049 160.408 1.00 49.50  ? 788 ARG B NE  1 
ATOM   12363 C  CZ  . ARG B 1 788 ? 229.738 242.538 161.084 1.00 49.50  ? 788 ARG B CZ  1 
ATOM   12364 N  NH1 . ARG B 1 788 ? 229.584 242.054 162.306 1.00 49.50  ? 788 ARG B NH1 1 
ATOM   12365 N  NH2 . ARG B 1 788 ? 230.943 242.513 160.521 1.00 49.50  ? 788 ARG B NH2 1 
ATOM   12366 N  N   . PRO B 1 789 ? 223.654 239.978 160.994 1.00 44.90  ? 789 PRO B N   1 
ATOM   12367 C  CA  . PRO B 1 789 ? 222.273 240.464 161.082 1.00 44.90  ? 789 PRO B CA  1 
ATOM   12368 C  C   . PRO B 1 789 ? 222.232 241.972 160.885 1.00 44.90  ? 789 PRO B C   1 
ATOM   12369 O  O   . PRO B 1 789 ? 223.018 242.712 161.477 1.00 44.90  ? 789 PRO B O   1 
ATOM   12370 C  CB  . PRO B 1 789 ? 221.842 240.057 162.495 1.00 44.90  ? 789 PRO B CB  1 
ATOM   12371 C  CG  . PRO B 1 789 ? 223.109 239.900 163.248 1.00 44.90  ? 789 PRO B CG  1 
ATOM   12372 C  CD  . PRO B 1 789 ? 224.122 239.415 162.271 1.00 44.90  ? 789 PRO B CD  1 
ATOM   12373 N  N   . LEU B 1 790 ? 221.312 242.425 160.047 1.00 47.39  ? 790 LEU B N   1 
ATOM   12374 C  CA  . LEU B 1 790 ? 221.277 243.813 159.622 1.00 47.39  ? 790 LEU B CA  1 
ATOM   12375 C  C   . LEU B 1 790 ? 219.880 244.383 159.794 1.00 47.39  ? 790 LEU B C   1 
ATOM   12376 O  O   . LEU B 1 790 ? 218.897 243.638 159.817 1.00 47.39  ? 790 LEU B O   1 
ATOM   12377 C  CB  . LEU B 1 790 ? 221.738 243.951 158.163 1.00 47.39  ? 790 LEU B CB  1 
ATOM   12378 C  CG  . LEU B 1 790 ? 220.861 243.497 156.999 1.00 47.39  ? 790 LEU B CG  1 
ATOM   12379 C  CD1 . LEU B 1 790 ? 221.370 244.114 155.716 1.00 47.39  ? 790 LEU B CD1 1 
ATOM   12380 C  CD2 . LEU B 1 790 ? 220.870 241.989 156.874 1.00 47.39  ? 790 LEU B CD2 1 
ATOM   12381 N  N   . PRO B 1 791 ? 219.759 245.705 159.934 1.00 51.13  ? 791 PRO B N   1 
ATOM   12382 C  CA  . PRO B 1 791 ? 218.448 246.300 160.210 1.00 51.13  ? 791 PRO B CA  1 
ATOM   12383 C  C   . PRO B 1 791 ? 217.543 246.301 158.993 1.00 51.13  ? 791 PRO B C   1 
ATOM   12384 O  O   . PRO B 1 791 ? 217.966 246.085 157.854 1.00 51.13  ? 791 PRO B O   1 
ATOM   12385 C  CB  . PRO B 1 791 ? 218.788 247.729 160.634 1.00 51.13  ? 791 PRO B CB  1 
ATOM   12386 C  CG  . PRO B 1 791 ? 220.057 248.012 159.958 1.00 51.13  ? 791 PRO B CG  1 
ATOM   12387 C  CD  . PRO B 1 791 ? 220.822 246.722 159.950 1.00 51.13  ? 791 PRO B CD  1 
ATOM   12388 N  N   . ALA B 1 792 ? 216.263 246.552 159.267 1.00 55.64  ? 792 ALA B N   1 
ATOM   12389 C  CA  . ALA B 1 792 ? 215.264 246.571 158.209 1.00 55.64  ? 792 ALA B CA  1 
ATOM   12390 C  C   . ALA B 1 792 ? 215.518 247.713 157.238 1.00 55.64  ? 792 ALA B C   1 
ATOM   12391 O  O   . ALA B 1 792 ? 215.098 247.657 156.077 1.00 55.64  ? 792 ALA B O   1 
ATOM   12392 C  CB  . ALA B 1 792 ? 213.865 246.676 158.813 1.00 55.64  ? 792 ALA B CB  1 
ATOM   12393 N  N   . GLU B 1 793 ? 216.197 248.763 157.695 1.00 58.85  ? 793 GLU B N   1 
ATOM   12394 C  CA  . GLU B 1 793 ? 216.500 249.878 156.811 1.00 58.85  ? 793 GLU B CA  1 
ATOM   12395 C  C   . GLU B 1 793 ? 217.614 249.559 155.829 1.00 58.85  ? 793 GLU B C   1 
ATOM   12396 O  O   . GLU B 1 793 ? 217.756 250.270 154.830 1.00 58.85  ? 793 GLU B O   1 
ATOM   12397 C  CB  . GLU B 1 793 ? 216.869 251.117 157.629 1.00 58.85  ? 793 GLU B CB  1 
ATOM   12398 C  CG  . GLU B 1 793 ? 217.990 250.898 158.631 1.00 58.85  ? 793 GLU B CG  1 
ATOM   12399 C  CD  . GLU B 1 793 ? 217.498 250.914 160.065 1.00 58.85  ? 793 GLU B CD  1 
ATOM   12400 O  OE1 . GLU B 1 793 ? 216.426 250.333 160.334 1.00 58.85  ? 793 GLU B OE1 1 
ATOM   12401 O  OE2 . GLU B 1 793 ? 218.184 251.507 160.924 1.00 58.85  ? 793 GLU B OE2 1 
ATOM   12402 N  N   . GLU B 1 794 ? 218.399 248.516 156.080 1.00 56.72  ? 794 GLU B N   1 
ATOM   12403 C  CA  . GLU B 1 794 ? 219.509 248.167 155.212 1.00 56.72  ? 794 GLU B CA  1 
ATOM   12404 C  C   . GLU B 1 794 ? 219.344 246.817 154.536 1.00 56.72  ? 794 GLU B C   1 
ATOM   12405 O  O   . GLU B 1 794 ? 220.122 246.500 153.631 1.00 56.72  ? 794 GLU B O   1 
ATOM   12406 C  CB  . GLU B 1 794 ? 220.824 248.189 155.998 1.00 56.72  ? 794 GLU B CB  1 
ATOM   12407 C  CG  . GLU B 1 794 ? 221.055 249.482 156.759 1.00 56.72  ? 794 GLU B CG  1 
ATOM   12408 C  CD  . GLU B 1 794 ? 222.497 249.657 157.187 1.00 56.72  ? 794 GLU B CD  1 
ATOM   12409 O  OE1 . GLU B 1 794 ? 223.318 248.762 156.894 1.00 56.72  ? 794 GLU B OE1 1 
ATOM   12410 O  OE2 . GLU B 1 794 ? 222.811 250.690 157.815 1.00 56.72  ? 794 GLU B OE2 1 
ATOM   12411 N  N   . ILE B 1 795 ? 218.373 246.009 154.948 1.00 57.72  ? 795 ILE B N   1 
ATOM   12412 C  CA  . ILE B 1 795 ? 218.107 244.751 154.252 1.00 57.72  ? 795 ILE B CA  1 
ATOM   12413 C  C   . ILE B 1 795 ? 217.663 244.974 152.805 1.00 57.72  ? 795 ILE B C   1 
ATOM   12414 O  O   . ILE B 1 795 ? 218.123 244.227 151.928 1.00 57.72  ? 795 ILE B O   1 
ATOM   12415 C  CB  . ILE B 1 795 ? 217.106 243.872 155.026 1.00 57.72  ? 795 ILE B CB  1 
ATOM   12416 C  CG1 . ILE B 1 795 ? 216.927 242.527 154.323 1.00 57.72  ? 795 ILE B CG1 1 
ATOM   12417 C  CG2 . ILE B 1 795 ? 215.775 244.542 155.211 1.00 57.72  ? 795 ILE B CG2 1 
ATOM   12418 C  CD1 . ILE B 1 795 ? 216.172 241.511 155.143 1.00 57.72  ? 795 ILE B CD1 1 
ATOM   12419 N  N   . PRO B 1 796 ? 216.799 245.950 152.472 1.00 57.68  ? 796 PRO B N   1 
ATOM   12420 C  CA  . PRO B 1 796 ? 216.349 246.020 151.072 1.00 57.68  ? 796 PRO B CA  1 
ATOM   12421 C  C   . PRO B 1 796 ? 217.469 246.391 150.126 1.00 57.68  ? 796 PRO B C   1 
ATOM   12422 O  O   . PRO B 1 796 ? 217.597 245.791 149.051 1.00 57.68  ? 796 PRO B O   1 
ATOM   12423 C  CB  . PRO B 1 796 ? 215.244 247.090 151.109 1.00 57.68  ? 796 PRO B CB  1 
ATOM   12424 C  CG  . PRO B 1 796 ? 215.005 247.379 152.553 1.00 57.68  ? 796 PRO B CG  1 
ATOM   12425 C  CD  . PRO B 1 796 ? 216.312 247.134 153.199 1.00 57.68  ? 796 PRO B CD  1 
ATOM   12426 N  N   . GLY B 1 797 ? 218.296 247.365 150.502 1.00 57.64  ? 797 GLY B N   1 
ATOM   12427 C  CA  . GLY B 1 797 ? 219.410 247.732 149.650 1.00 57.64  ? 797 GLY B CA  1 
ATOM   12428 C  C   . GLY B 1 797 ? 220.371 246.581 149.438 1.00 57.64  ? 797 GLY B C   1 
ATOM   12429 O  O   . GLY B 1 797 ? 220.804 246.316 148.315 1.00 57.64  ? 797 GLY B O   1 
ATOM   12430 N  N   . TRP B 1 798 ? 220.711 245.877 150.518 1.00 56.63  ? 798 TRP B N   1 
ATOM   12431 C  CA  . TRP B 1 798 ? 221.647 244.763 150.411 1.00 56.63  ? 798 TRP B CA  1 
ATOM   12432 C  C   . TRP B 1 798 ? 221.079 243.647 149.549 1.00 56.63  ? 798 TRP B C   1 
ATOM   12433 O  O   . TRP B 1 798 ? 221.786 243.078 148.710 1.00 56.63  ? 798 TRP B O   1 
ATOM   12434 C  CB  . TRP B 1 798 ? 221.996 244.240 151.803 1.00 56.63  ? 798 TRP B CB  1 
ATOM   12435 C  CG  . TRP B 1 798 ? 223.027 243.157 151.809 1.00 56.63  ? 798 TRP B CG  1 
ATOM   12436 C  CD1 . TRP B 1 798 ? 224.378 243.316 151.822 1.00 56.63  ? 798 TRP B CD1 1 
ATOM   12437 C  CD2 . TRP B 1 798 ? 222.789 241.748 151.823 1.00 56.63  ? 798 TRP B CD2 1 
ATOM   12438 N  NE1 . TRP B 1 798 ? 224.997 242.095 151.835 1.00 56.63  ? 798 TRP B NE1 1 
ATOM   12439 C  CE2 . TRP B 1 798 ? 224.041 241.116 151.836 1.00 56.63  ? 798 TRP B CE2 1 
ATOM   12440 C  CE3 . TRP B 1 798 ? 221.640 240.961 151.823 1.00 56.63  ? 798 TRP B CE3 1 
ATOM   12441 C  CZ2 . TRP B 1 798 ? 224.176 239.736 151.847 1.00 56.63  ? 798 TRP B CZ2 1 
ATOM   12442 C  CZ3 . TRP B 1 798 ? 221.777 239.593 151.834 1.00 56.63  ? 798 TRP B CZ3 1 
ATOM   12443 C  CH2 . TRP B 1 798 ? 223.035 238.994 151.845 1.00 56.63  ? 798 TRP B CH2 1 
ATOM   12444 N  N   . MET B 1 799 ? 219.798 243.327 149.733 1.00 61.89  ? 799 MET B N   1 
ATOM   12445 C  CA  . MET B 1 799 ? 219.198 242.243 148.967 1.00 61.89  ? 799 MET B CA  1 
ATOM   12446 C  C   . MET B 1 799 ? 219.015 242.622 147.501 1.00 61.89  ? 799 MET B C   1 
ATOM   12447 O  O   . MET B 1 799 ? 219.045 241.745 146.630 1.00 61.89  ? 799 MET B O   1 
ATOM   12448 C  CB  . MET B 1 799 ? 217.868 241.833 149.598 1.00 61.89  ? 799 MET B CB  1 
ATOM   12449 C  CG  . MET B 1 799 ? 216.668 242.632 149.129 1.00 61.89  ? 799 MET B CG  1 
ATOM   12450 S  SD  . MET B 1 799 ? 215.111 241.771 149.408 1.00 61.89  ? 799 MET B SD  1 
ATOM   12451 C  CE  . MET B 1 799 ? 215.039 240.718 147.962 1.00 61.89  ? 799 MET B CE  1 
ATOM   12452 N  N   . SER B 1 800 ? 218.824 243.912 147.205 1.00 61.85  ? 800 SER B N   1 
ATOM   12453 C  CA  . SER B 1 800 ? 218.728 244.343 145.815 1.00 61.85  ? 800 SER B CA  1 
ATOM   12454 C  C   . SER B 1 800 ? 220.091 244.422 145.145 1.00 61.85  ? 800 SER B C   1 
ATOM   12455 O  O   . SER B 1 800 ? 220.198 244.172 143.940 1.00 61.85  ? 800 SER B O   1 
ATOM   12456 C  CB  . SER B 1 800 ? 218.036 245.702 145.730 1.00 61.85  ? 800 SER B CB  1 
ATOM   12457 O  OG  . SER B 1 800 ? 218.851 246.718 146.286 1.00 61.85  ? 800 SER B OG  1 
ATOM   12458 N  N   . SER B 1 801 ? 221.135 244.757 145.901 1.00 62.76  ? 801 SER B N   1 
ATOM   12459 C  CA  . SER B 1 801 ? 222.447 245.010 145.325 1.00 62.76  ? 801 SER B CA  1 
ATOM   12460 C  C   . SER B 1 801 ? 223.297 243.749 145.209 1.00 62.76  ? 801 SER B C   1 
ATOM   12461 O  O   . SER B 1 801 ? 223.898 243.503 144.159 1.00 62.76  ? 801 SER B O   1 
ATOM   12462 C  CB  . SER B 1 801 ? 223.186 246.059 146.159 1.00 62.76  ? 801 SER B CB  1 
ATOM   12463 O  OG  . SER B 1 801 ? 224.477 246.308 145.634 1.00 62.76  ? 801 SER B OG  1 
ATOM   12464 N  N   . VAL B 1 802 ? 223.365 242.944 146.266 1.00 58.89  ? 802 VAL B N   1 
ATOM   12465 C  CA  . VAL B 1 802 ? 224.321 241.847 146.341 1.00 58.89  ? 802 VAL B CA  1 
ATOM   12466 C  C   . VAL B 1 802 ? 223.616 240.538 146.017 1.00 58.89  ? 802 VAL B C   1 
ATOM   12467 O  O   . VAL B 1 802 ? 222.679 240.134 146.717 1.00 58.89  ? 802 VAL B O   1 
ATOM   12468 C  CB  . VAL B 1 802 ? 224.989 241.786 147.723 1.00 58.89  ? 802 VAL B CB  1 
ATOM   12469 C  CG1 . VAL B 1 802 ? 225.996 240.654 147.767 1.00 58.89  ? 802 VAL B CG1 1 
ATOM   12470 C  CG2 . VAL B 1 802 ? 225.656 243.113 148.046 1.00 58.89  ? 802 VAL B CG2 1 
ATOM   12471 N  N   . LEU B 1 803 ? 224.059 239.886 144.946 1.00 60.06  ? 803 LEU B N   1 
ATOM   12472 C  CA  . LEU B 1 803 ? 223.621 238.553 144.556 1.00 60.06  ? 803 LEU B CA  1 
ATOM   12473 C  C   . LEU B 1 803 ? 224.547 238.007 143.474 1.00 60.06  ? 803 LEU B C   1 
ATOM   12474 O  O   . LEU B 1 803 ? 224.767 238.682 142.460 1.00 60.06  ? 803 LEU B O   1 
ATOM   12475 C  CB  . LEU B 1 803 ? 222.178 238.585 144.046 1.00 60.06  ? 803 LEU B CB  1 
ATOM   12476 C  CG  . LEU B 1 803 ? 221.718 237.361 143.254 1.00 60.06  ? 803 LEU B CG  1 
ATOM   12477 C  CD1 . LEU B 1 803 ? 221.535 236.164 144.169 1.00 60.06  ? 803 LEU B CD1 1 
ATOM   12478 C  CD2 . LEU B 1 803 ? 220.440 237.664 142.500 1.00 60.06  ? 803 LEU B CD2 1 
ATOM   12479 N  N   . PRO B 1 804 ? 225.113 236.805 143.638 1.00 58.66  ? 804 PRO B N   1 
ATOM   12480 C  CA  . PRO B 1 804 ? 225.135 235.951 144.824 1.00 58.66  ? 804 PRO B CA  1 
ATOM   12481 C  C   . PRO B 1 804 ? 226.425 236.127 145.610 1.00 58.66  ? 804 PRO B C   1 
ATOM   12482 O  O   . PRO B 1 804 ? 227.323 236.836 145.169 1.00 58.66  ? 804 PRO B O   1 
ATOM   12483 C  CB  . PRO B 1 804 ? 225.035 234.557 144.217 1.00 58.66  ? 804 PRO B CB  1 
ATOM   12484 C  CG  . PRO B 1 804 ? 225.876 234.675 142.978 1.00 58.66  ? 804 PRO B CG  1 
ATOM   12485 C  CD  . PRO B 1 804 ? 225.653 236.087 142.469 1.00 58.66  ? 804 PRO B CD  1 
ATOM   12486 N  N   . LEU B 1 805 ? 226.561 235.491 146.772 1.00 62.07  ? 805 LEU B N   1 
ATOM   12487 C  CA  . LEU B 1 805 ? 227.783 235.569 147.560 1.00 62.07  ? 805 LEU B CA  1 
ATOM   12488 C  C   . LEU B 1 805 ? 228.597 234.286 147.506 1.00 62.07  ? 805 LEU B C   1 
ATOM   12489 O  O   . LEU B 1 805 ? 229.526 234.123 148.303 1.00 62.07  ? 805 LEU B O   1 
ATOM   12490 C  CB  . LEU B 1 805 ? 227.465 235.914 149.016 1.00 62.07  ? 805 LEU B CB  1 
ATOM   12491 C  CG  . LEU B 1 805 ? 227.009 237.343 149.304 1.00 62.07  ? 805 LEU B CG  1 
ATOM   12492 C  CD1 . LEU B 1 805 ? 225.495 237.439 149.213 1.00 62.07  ? 805 LEU B CD1 1 
ATOM   12493 C  CD2 . LEU B 1 805 ? 227.504 237.807 150.663 1.00 62.07  ? 805 LEU B CD2 1 
ATOM   12494 N  N   . LYS B 1 806 ? 228.267 233.372 146.599 1.00 64.27  ? 806 LYS B N   1 
ATOM   12495 C  CA  . LYS B 1 806 ? 228.989 232.110 146.488 1.00 64.27  ? 806 LYS B CA  1 
ATOM   12496 C  C   . LYS B 1 806 ? 230.465 232.343 146.189 1.00 64.27  ? 806 LYS B C   1 
ATOM   12497 O  O   . LYS B 1 806 ? 231.325 231.548 146.565 1.00 64.27  ? 806 LYS B O   1 
ATOM   12498 C  CB  . LYS B 1 806 ? 228.369 231.230 145.401 1.00 64.27  ? 806 LYS B CB  1 
ATOM   12499 C  CG  . LYS B 1 806 ? 228.951 229.826 145.342 1.00 64.27  ? 806 LYS B CG  1 
ATOM   12500 C  CD  . LYS B 1 806 ? 228.428 229.054 144.145 1.00 64.27  ? 806 LYS B CD  1 
ATOM   12501 C  CE  . LYS B 1 806 ? 228.957 227.629 144.136 1.00 64.27  ? 806 LYS B CE  1 
ATOM   12502 N  NZ  . LYS B 1 806 ? 230.433 227.587 143.948 1.00 64.27  ? 806 LYS B NZ  1 
HETATM 12503 C  CHA . HEM C 2 .   ? 220.216 200.172 311.956 1.00 126.15 ? 901 HEM A CHA 1 
HETATM 12504 C  CHB . HEM C 2 .   ? 215.936 202.049 310.745 1.00 126.15 ? 901 HEM A CHB 1 
HETATM 12505 C  CHC . HEM C 2 .   ? 217.108 206.070 313.147 1.00 126.15 ? 901 HEM A CHC 1 
HETATM 12506 C  CHD . HEM C 2 .   ? 220.510 203.526 315.430 1.00 126.15 ? 901 HEM A CHD 1 
HETATM 12507 C  C1A . HEM C 2 .   ? 219.009 200.357 311.335 1.00 126.15 ? 901 HEM A C1A 1 
HETATM 12508 C  C2A . HEM C 2 .   ? 218.446 199.532 310.289 1.00 126.15 ? 901 HEM A C2A 1 
HETATM 12509 C  C3A . HEM C 2 .   ? 217.257 200.050 309.959 1.00 126.15 ? 901 HEM A C3A 1 
HETATM 12510 C  C4A . HEM C 2 .   ? 217.037 201.223 310.778 1.00 126.15 ? 901 HEM A C4A 1 
HETATM 12511 C  CMA . HEM C 2 .   ? 216.271 199.518 308.895 1.00 126.15 ? 901 HEM A CMA 1 
HETATM 12512 C  CAA . HEM C 2 .   ? 219.118 198.269 309.699 1.00 126.15 ? 901 HEM A CAA 1 
HETATM 12513 C  CBA . HEM C 2 .   ? 219.516 198.454 308.234 1.00 126.15 ? 901 HEM A CBA 1 
HETATM 12514 C  CGA . HEM C 2 .   ? 220.449 199.625 308.061 1.00 126.15 ? 901 HEM A CGA 1 
HETATM 12515 O  O1A . HEM C 2 .   ? 220.500 200.184 306.935 1.00 126.15 ? 901 HEM A O1A 1 
HETATM 12516 O  O2A . HEM C 2 .   ? 221.141 200.004 309.040 1.00 126.15 ? 901 HEM A O2A 1 
HETATM 12517 C  C1B . HEM C 2 .   ? 215.912 203.338 311.221 1.00 126.15 ? 901 HEM A C1B 1 
HETATM 12518 C  C2B . HEM C 2 .   ? 214.942 204.354 310.882 1.00 126.15 ? 901 HEM A C2B 1 
HETATM 12519 C  C3B . HEM C 2 .   ? 215.262 205.470 311.558 1.00 126.15 ? 901 HEM A C3B 1 
HETATM 12520 C  C4B . HEM C 2 .   ? 216.454 205.186 312.324 1.00 126.15 ? 901 HEM A C4B 1 
HETATM 12521 C  CMB . HEM C 2 .   ? 213.761 204.107 309.917 1.00 126.15 ? 901 HEM A CMB 1 
HETATM 12522 C  CAB . HEM C 2 .   ? 214.583 206.863 311.569 1.00 126.15 ? 901 HEM A CAB 1 
HETATM 12523 C  CBB . HEM C 2 .   ? 213.648 207.258 310.697 1.00 126.15 ? 901 HEM A CBB 1 
HETATM 12524 C  C1C . HEM C 2 .   ? 218.157 205.749 313.975 1.00 126.15 ? 901 HEM A C1C 1 
HETATM 12525 C  C2C . HEM C 2 .   ? 218.866 206.655 314.844 1.00 126.15 ? 901 HEM A C2C 1 
HETATM 12526 C  C3C . HEM C 2 .   ? 219.816 205.973 315.481 1.00 126.15 ? 901 HEM A C3C 1 
HETATM 12527 C  C4C . HEM C 2 .   ? 219.733 204.591 315.038 1.00 126.15 ? 901 HEM A C4C 1 
HETATM 12528 C  CMC . HEM C 2 .   ? 218.578 208.163 314.993 1.00 126.15 ? 901 HEM A CMC 1 
HETATM 12529 C  CAC . HEM C 2 .   ? 220.793 206.600 316.503 1.00 126.15 ? 901 HEM A CAC 1 
HETATM 12530 C  CBC . HEM C 2 .   ? 221.825 205.930 317.025 1.00 126.15 ? 901 HEM A CBC 1 
HETATM 12531 C  C1D . HEM C 2 .   ? 220.751 202.402 314.675 1.00 126.15 ? 901 HEM A C1D 1 
HETATM 12532 C  C2D . HEM C 2 .   ? 221.761 201.399 314.938 1.00 126.15 ? 901 HEM A C2D 1 
HETATM 12533 C  C3D . HEM C 2 .   ? 221.690 200.475 313.978 1.00 126.15 ? 901 HEM A C3D 1 
HETATM 12534 C  C4D . HEM C 2 .   ? 220.624 200.856 313.073 1.00 126.15 ? 901 HEM A C4D 1 
HETATM 12535 C  CMD . HEM C 2 .   ? 222.753 201.404 316.121 1.00 126.15 ? 901 HEM A CMD 1 
HETATM 12536 C  CAD . HEM C 2 .   ? 222.583 199.217 313.881 1.00 126.15 ? 901 HEM A CAD 1 
HETATM 12537 C  CBD . HEM C 2 .   ? 223.421 199.240 312.606 1.00 126.15 ? 901 HEM A CBD 1 
HETATM 12538 C  CGD . HEM C 2 .   ? 224.280 198.004 312.550 1.00 126.15 ? 901 HEM A CGD 1 
HETATM 12539 O  O1D . HEM C 2 .   ? 225.052 197.853 311.567 1.00 126.15 ? 901 HEM A O1D 1 
HETATM 12540 O  O2D . HEM C 2 .   ? 224.194 197.169 313.487 1.00 126.15 ? 901 HEM A O2D 1 
HETATM 12541 N  NA  . HEM C 2 .   ? 218.130 201.381 311.607 1.00 126.15 ? 901 HEM A NA  1 
HETATM 12542 N  NB  . HEM C 2 .   ? 216.821 203.879 312.099 1.00 126.15 ? 901 HEM A NB  1 
HETATM 12543 N  NC  . HEM C 2 .   ? 218.709 204.498 314.121 1.00 126.15 ? 901 HEM A NC  1 
HETATM 12544 N  ND  . HEM C 2 .   ? 220.074 202.036 313.530 1.00 126.15 ? 901 HEM A ND  1 
HETATM 12545 FE FE  . HEM C 2 .   ? 218.427 202.932 312.888 1.00 126.15 ? 901 HEM A FE  1 
HETATM 12546 C  CHA . HEM D 2 .   ? 236.006 227.888 302.074 1.00 141.78 ? 901 HEM B CHA 1 
HETATM 12547 C  CHB . HEM D 2 .   ? 238.424 226.099 298.323 1.00 141.78 ? 901 HEM B CHB 1 
HETATM 12548 C  CHC . HEM D 2 .   ? 241.237 223.632 301.356 1.00 141.78 ? 901 HEM B CHC 1 
HETATM 12549 C  CHD . HEM D 2 .   ? 239.191 225.864 305.097 1.00 141.78 ? 901 HEM B CHD 1 
HETATM 12550 C  C1A . HEM D 2 .   ? 236.462 227.716 300.795 1.00 141.78 ? 901 HEM B C1A 1 
HETATM 12551 C  C2A . HEM D 2 .   ? 236.116 228.499 299.630 1.00 141.78 ? 901 HEM B C2A 1 
HETATM 12552 C  C3A . HEM D 2 .   ? 236.793 228.001 298.591 1.00 141.78 ? 901 HEM B C3A 1 
HETATM 12553 C  C4A . HEM D 2 .   ? 237.585 226.889 299.069 1.00 141.78 ? 901 HEM B C4A 1 
HETATM 12554 C  CMA . HEM D 2 .   ? 236.753 228.502 297.130 1.00 141.78 ? 901 HEM B CMA 1 
HETATM 12555 C  CAA . HEM D 2 .   ? 235.142 229.697 299.606 1.00 141.78 ? 901 HEM B CAA 1 
HETATM 12556 C  CBA . HEM D 2 .   ? 233.835 229.300 298.924 1.00 141.78 ? 901 HEM B CBA 1 
HETATM 12557 C  CGA . HEM D 2 .   ? 232.991 230.526 298.696 1.00 141.78 ? 901 HEM B CGA 1 
HETATM 12558 O  O1A . HEM D 2 .   ? 231.853 230.382 298.179 1.00 141.78 ? 901 HEM B O1A 1 
HETATM 12559 O  O2A . HEM D 2 .   ? 233.454 231.647 299.029 1.00 141.78 ? 901 HEM B O2A 1 
HETATM 12560 C  C1B . HEM D 2 .   ? 239.196 225.099 298.861 1.00 141.78 ? 901 HEM B C1B 1 
HETATM 12561 C  C2B . HEM D 2 .   ? 239.479 223.815 298.252 1.00 141.78 ? 901 HEM B C2B 1 
HETATM 12562 C  C3B . HEM D 2 .   ? 240.267 223.127 299.096 1.00 141.78 ? 901 HEM B C3B 1 
HETATM 12563 C  C4B . HEM D 2 .   ? 240.487 223.966 300.256 1.00 141.78 ? 901 HEM B C4B 1 
HETATM 12564 C  CMB . HEM D 2 .   ? 238.940 223.394 296.865 1.00 141.78 ? 901 HEM B CMB 1 
HETATM 12565 C  CAB . HEM D 2 .   ? 240.874 221.704 298.968 1.00 141.78 ? 901 HEM B CAB 1 
HETATM 12566 C  CBB . HEM D 2 .   ? 240.628 220.852 297.965 1.00 141.78 ? 901 HEM B CBB 1 
HETATM 12567 C  C1C . HEM D 2 .   ? 240.897 223.963 302.641 1.00 141.78 ? 901 HEM B C1C 1 
HETATM 12568 C  C2C . HEM D 2 .   ? 241.365 223.309 303.836 1.00 141.78 ? 901 HEM B C2C 1 
HETATM 12569 C  C3C . HEM D 2 .   ? 240.807 223.911 304.885 1.00 141.78 ? 901 HEM B C3C 1 
HETATM 12570 C  C4C . HEM D 2 .   ? 239.961 224.981 304.380 1.00 141.78 ? 901 HEM B C4C 1 
HETATM 12571 C  CMC . HEM D 2 .   ? 242.342 222.116 303.877 1.00 141.78 ? 901 HEM B CMC 1 
HETATM 12572 C  CAC . HEM D 2 .   ? 241.066 223.494 306.353 1.00 141.78 ? 901 HEM B CAC 1 
HETATM 12573 C  CBC . HEM D 2 .   ? 240.426 224.044 307.390 1.00 141.78 ? 901 HEM B CBC 1 
HETATM 12574 C  C1D . HEM D 2 .   ? 238.295 226.750 304.544 1.00 141.78 ? 901 HEM B C1D 1 
HETATM 12575 C  C2D . HEM D 2 .   ? 237.902 228.028 305.102 1.00 141.78 ? 901 HEM B C2D 1 
HETATM 12576 C  C3D . HEM D 2 .   ? 237.019 228.588 304.274 1.00 141.78 ? 901 HEM B C3D 1 
HETATM 12577 C  C4D . HEM D 2 .   ? 236.822 227.686 303.159 1.00 141.78 ? 901 HEM B C4D 1 
HETATM 12578 C  CMD . HEM D 2 .   ? 238.408 228.633 306.429 1.00 141.78 ? 901 HEM B CMD 1 
HETATM 12579 C  CAD . HEM D 2 .   ? 236.339 229.959 304.476 1.00 141.78 ? 901 HEM B CAD 1 
HETATM 12580 C  CBD . HEM D 2 .   ? 234.855 229.765 304.762 1.00 141.78 ? 901 HEM B CBD 1 
HETATM 12581 C  CGD . HEM D 2 .   ? 234.192 231.106 304.934 1.00 141.78 ? 901 HEM B CGD 1 
HETATM 12582 O  O1D . HEM D 2 .   ? 234.887 232.144 304.787 1.00 141.78 ? 901 HEM B O1D 1 
HETATM 12583 O  O2D . HEM D 2 .   ? 232.967 231.137 305.218 1.00 141.78 ? 901 HEM B O2D 1 
HETATM 12584 N  NA  . HEM D 2 .   ? 237.363 226.744 300.420 1.00 141.78 ? 901 HEM B NA  1 
HETATM 12585 N  NB  . HEM D 2 .   ? 239.817 225.159 300.089 1.00 141.78 ? 901 HEM B NB  1 
HETATM 12586 N  NC  . HEM D 2 .   ? 240.043 224.978 303.005 1.00 141.78 ? 901 HEM B NC  1 
HETATM 12587 N  ND  . HEM D 2 .   ? 237.626 226.579 303.348 1.00 141.78 ? 901 HEM B ND  1 
HETATM 12588 FE FE  . HEM D 2 .   ? 238.742 225.897 301.703 1.00 141.78 ? 901 HEM B FE  1 
# 
