data_9BGJ
# 
_entry.id   9BGJ 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.402 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BGJ         pdb_00009bgj 10.2210/pdb9bgj/pdb 
WWPDB D_1000283205 ?            ?                   
EMDB  EMD-44514    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-03-05 ? 
2 'EM metadata'     1 0 2025-03-05 ? 
3 'Half map'        1 0 2025-03-05 1 
4 'Half map'        1 0 2025-03-05 2 
5 Image             1 0 2025-03-05 ? 
6 Mask              1 0 2025-03-05 1 
7 'Primary map'     1 0 2025-03-05 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Half map'        repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 Image             repository 'Initial release' ? ? 
6 6 Mask              repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BGJ 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'SgrAI mutant K242A endonuclease DNA-bound dimer with Mg2+ and intact primary site DNA' 
_pdbx_database_related.db_id          EMD-44514 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 dlyumkis@salk.edu         Dmitry Lyumkis ? 'principal investigator/group leader' 0000-0002-8124-7472 
3 nhorton@email.arizona.edu Nancy  Horton  C 'principal investigator/group leader' 0000-0003-2710-8284 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Shan, Z.'     1 0000-0003-4983-3575 
'Lyumkis, D.'  2 0000-0002-8124-7472 
'Horton, N.C.' 3 0000-0003-2710-8284 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            J.Biol.Chem. 
_citation.journal_id_ASTM           JBCHA3 
_citation.journal_id_CSD            0071 
_citation.journal_id_ISSN           1083-351X 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            300 
_citation.language                  ? 
_citation.page_first                107576 
_citation.page_last                 107576 
_citation.title                     'Two-metal ion mechanism of DNA cleavage by activated, filamentous SgrAI.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.jbc.2024.107576 
_citation.pdbx_database_id_PubMed   39009341 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Shan, Z.'         1 ? 
primary 'Rivero-Gamez, A.' 2 ? 
primary 'Lyumkis, D.'      3 ? 
primary 'Horton, N.C.'     4 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'SgraIR restriction enzyme' 39741.816 2 ? K242A ? ? 
2 polymer     syn '40-1 DNA'                  24674.738 2 ? ?     ? ? 
3 non-polymer syn 'MAGNESIUM ION'             24.305    2 ? ?     ? ? 
4 water       nat water                       18.015    9 ? ?     ? ? 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)'        no no 
;MPFTYSIEATRNLATTERCIQDIRNAPVRNRSTQFQLAQQNMLAYTFGEVIPGFASAGINGMDYRDVIGRPVENAVTEGT
HFFRDDFRVDSNAKAKVAGDIFEIVSSAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLPRSFDWVSLL
VPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQNDEMWREEIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVA
FARSLRSDRLYQPLYEANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAEGRSAVHRAIRELYVPPTAA
DLARRFFAFLNERMEKVNGENLYFQSHHHHHH
;
;MPFTYSIEATRNLATTERCIQDIRNAPVRNRSTQFQLAQQNMLAYTFGEVIPGFASAGINGMDYRDVIGRPVENAVTEGT
HFFRDDFRVDSNAKAKVAGDIFEIVSSAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLPRSFDWVSLL
VPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQNDEMWREEIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVA
FARSLRSDRLYQPLYEANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAEGRSAVHRAIRELYVPPTAA
DLARRFFAFLNERMEKVNGENLYFQSHHHHHH
;
A,B ? 
2 polydeoxyribonucleotide no no 
;(DG)(DA)(DT)(DG)(DC)(DG)(DT)(DG)(DG)(DG)(DT)(DC)(DT)(DT)(DC)(DA)(DC)(DA)(DC)(DC)
(DG)(DG)(DT)(DG)(DG)(DA)(DT)(DG)(DC)(DG)(DT)(DG)(DG)(DG)(DT)(DC)(DT)(DT)(DC)(DA)
(DT)(DG)(DA)(DA)(DG)(DA)(DC)(DC)(DC)(DA)(DC)(DG)(DC)(DA)(DT)(DC)(DC)(DA)(DC)(DC)
(DG)(DG)(DT)(DG)(DT)(DG)(DA)(DA)(DG)(DA)(DC)(DC)(DC)(DA)(DC)(DG)(DC)(DA)(DT)(DC)
;
GATGCGTGGGTCTTCACACCGGTGGATGCGTGGGTCTTCATGAAGACCCACGCATCCACCGGTGTGAAGACCCACGCATC C,D ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
3 'MAGNESIUM ION' MG  
4 water           HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   PRO n 
1 3   PHE n 
1 4   THR n 
1 5   TYR n 
1 6   SER n 
1 7   ILE n 
1 8   GLU n 
1 9   ALA n 
1 10  THR n 
1 11  ARG n 
1 12  ASN n 
1 13  LEU n 
1 14  ALA n 
1 15  THR n 
1 16  THR n 
1 17  GLU n 
1 18  ARG n 
1 19  CYS n 
1 20  ILE n 
1 21  GLN n 
1 22  ASP n 
1 23  ILE n 
1 24  ARG n 
1 25  ASN n 
1 26  ALA n 
1 27  PRO n 
1 28  VAL n 
1 29  ARG n 
1 30  ASN n 
1 31  ARG n 
1 32  SER n 
1 33  THR n 
1 34  GLN n 
1 35  PHE n 
1 36  GLN n 
1 37  LEU n 
1 38  ALA n 
1 39  GLN n 
1 40  GLN n 
1 41  ASN n 
1 42  MET n 
1 43  LEU n 
1 44  ALA n 
1 45  TYR n 
1 46  THR n 
1 47  PHE n 
1 48  GLY n 
1 49  GLU n 
1 50  VAL n 
1 51  ILE n 
1 52  PRO n 
1 53  GLY n 
1 54  PHE n 
1 55  ALA n 
1 56  SER n 
1 57  ALA n 
1 58  GLY n 
1 59  ILE n 
1 60  ASN n 
1 61  GLY n 
1 62  MET n 
1 63  ASP n 
1 64  TYR n 
1 65  ARG n 
1 66  ASP n 
1 67  VAL n 
1 68  ILE n 
1 69  GLY n 
1 70  ARG n 
1 71  PRO n 
1 72  VAL n 
1 73  GLU n 
1 74  ASN n 
1 75  ALA n 
1 76  VAL n 
1 77  THR n 
1 78  GLU n 
1 79  GLY n 
1 80  THR n 
1 81  HIS n 
1 82  PHE n 
1 83  PHE n 
1 84  ARG n 
1 85  ASP n 
1 86  ASP n 
1 87  PHE n 
1 88  ARG n 
1 89  VAL n 
1 90  ASP n 
1 91  SER n 
1 92  ASN n 
1 93  ALA n 
1 94  LYS n 
1 95  ALA n 
1 96  LYS n 
1 97  VAL n 
1 98  ALA n 
1 99  GLY n 
1 100 ASP n 
1 101 ILE n 
1 102 PHE n 
1 103 GLU n 
1 104 ILE n 
1 105 VAL n 
1 106 SER n 
1 107 SER n 
1 108 ALA n 
1 109 VAL n 
1 110 MET n 
1 111 TRP n 
1 112 ASN n 
1 113 CYS n 
1 114 ALA n 
1 115 ALA n 
1 116 ARG n 
1 117 TRP n 
1 118 ASN n 
1 119 SER n 
1 120 LEU n 
1 121 MET n 
1 122 VAL n 
1 123 GLY n 
1 124 GLU n 
1 125 GLY n 
1 126 TRP n 
1 127 ARG n 
1 128 SER n 
1 129 GLN n 
1 130 PRO n 
1 131 ARG n 
1 132 TYR n 
1 133 SER n 
1 134 ARG n 
1 135 PRO n 
1 136 THR n 
1 137 LEU n 
1 138 SER n 
1 139 PRO n 
1 140 SER n 
1 141 PRO n 
1 142 ARG n 
1 143 ARG n 
1 144 GLN n 
1 145 VAL n 
1 146 ALA n 
1 147 VAL n 
1 148 LEU n 
1 149 ASN n 
1 150 LEU n 
1 151 PRO n 
1 152 ARG n 
1 153 SER n 
1 154 PHE n 
1 155 ASP n 
1 156 TRP n 
1 157 VAL n 
1 158 SER n 
1 159 LEU n 
1 160 LEU n 
1 161 VAL n 
1 162 PRO n 
1 163 GLU n 
1 164 SER n 
1 165 GLN n 
1 166 GLU n 
1 167 VAL n 
1 168 ILE n 
1 169 GLU n 
1 170 GLU n 
1 171 PHE n 
1 172 ARG n 
1 173 ALA n 
1 174 GLY n 
1 175 LEU n 
1 176 ARG n 
1 177 LYS n 
1 178 ASP n 
1 179 GLY n 
1 180 LEU n 
1 181 GLY n 
1 182 LEU n 
1 183 PRO n 
1 184 THR n 
1 185 SER n 
1 186 THR n 
1 187 PRO n 
1 188 ASP n 
1 189 LEU n 
1 190 ALA n 
1 191 VAL n 
1 192 VAL n 
1 193 VAL n 
1 194 LEU n 
1 195 PRO n 
1 196 GLU n 
1 197 GLU n 
1 198 PHE n 
1 199 GLN n 
1 200 ASN n 
1 201 ASP n 
1 202 GLU n 
1 203 MET n 
1 204 TRP n 
1 205 ARG n 
1 206 GLU n 
1 207 GLU n 
1 208 ILE n 
1 209 ALA n 
1 210 GLY n 
1 211 LEU n 
1 212 THR n 
1 213 ARG n 
1 214 PRO n 
1 215 ASN n 
1 216 GLN n 
1 217 ILE n 
1 218 LEU n 
1 219 LEU n 
1 220 SER n 
1 221 GLY n 
1 222 ALA n 
1 223 TYR n 
1 224 GLN n 
1 225 ARG n 
1 226 LEU n 
1 227 GLN n 
1 228 GLY n 
1 229 ARG n 
1 230 VAL n 
1 231 GLN n 
1 232 PRO n 
1 233 GLY n 
1 234 GLU n 
1 235 ILE n 
1 236 SER n 
1 237 LEU n 
1 238 ALA n 
1 239 VAL n 
1 240 ALA n 
1 241 PHE n 
1 242 ALA n 
1 243 ARG n 
1 244 SER n 
1 245 LEU n 
1 246 ARG n 
1 247 SER n 
1 248 ASP n 
1 249 ARG n 
1 250 LEU n 
1 251 TYR n 
1 252 GLN n 
1 253 PRO n 
1 254 LEU n 
1 255 TYR n 
1 256 GLU n 
1 257 ALA n 
1 258 ASN n 
1 259 VAL n 
1 260 MET n 
1 261 GLN n 
1 262 LEU n 
1 263 LEU n 
1 264 LEU n 
1 265 GLU n 
1 266 GLY n 
1 267 LYS n 
1 268 LEU n 
1 269 GLY n 
1 270 ALA n 
1 271 PRO n 
1 272 LYS n 
1 273 VAL n 
1 274 GLU n 
1 275 PHE n 
1 276 GLU n 
1 277 VAL n 
1 278 HIS n 
1 279 THR n 
1 280 LEU n 
1 281 ALA n 
1 282 PRO n 
1 283 GLU n 
1 284 GLY n 
1 285 THR n 
1 286 ASN n 
1 287 ALA n 
1 288 PHE n 
1 289 VAL n 
1 290 THR n 
1 291 TYR n 
1 292 GLU n 
1 293 ALA n 
1 294 ALA n 
1 295 SER n 
1 296 LEU n 
1 297 TYR n 
1 298 GLY n 
1 299 LEU n 
1 300 ALA n 
1 301 GLU n 
1 302 GLY n 
1 303 ARG n 
1 304 SER n 
1 305 ALA n 
1 306 VAL n 
1 307 HIS n 
1 308 ARG n 
1 309 ALA n 
1 310 ILE n 
1 311 ARG n 
1 312 GLU n 
1 313 LEU n 
1 314 TYR n 
1 315 VAL n 
1 316 PRO n 
1 317 PRO n 
1 318 THR n 
1 319 ALA n 
1 320 ALA n 
1 321 ASP n 
1 322 LEU n 
1 323 ALA n 
1 324 ARG n 
1 325 ARG n 
1 326 PHE n 
1 327 PHE n 
1 328 ALA n 
1 329 PHE n 
1 330 LEU n 
1 331 ASN n 
1 332 GLU n 
1 333 ARG n 
1 334 MET n 
1 335 GLU n 
1 336 LYS n 
1 337 VAL n 
1 338 ASN n 
1 339 GLY n 
1 340 GLU n 
1 341 ASN n 
1 342 LEU n 
1 343 TYR n 
1 344 PHE n 
1 345 GLN n 
1 346 SER n 
1 347 HIS n 
1 348 HIS n 
1 349 HIS n 
1 350 HIS n 
1 351 HIS n 
1 352 HIS n 
2 1   DG  n 
2 2   DA  n 
2 3   DT  n 
2 4   DG  n 
2 5   DC  n 
2 6   DG  n 
2 7   DT  n 
2 8   DG  n 
2 9   DG  n 
2 10  DG  n 
2 11  DT  n 
2 12  DC  n 
2 13  DT  n 
2 14  DT  n 
2 15  DC  n 
2 16  DA  n 
2 17  DC  n 
2 18  DA  n 
2 19  DC  n 
2 20  DC  n 
2 21  DG  n 
2 22  DG  n 
2 23  DT  n 
2 24  DG  n 
2 25  DG  n 
2 26  DA  n 
2 27  DT  n 
2 28  DG  n 
2 29  DC  n 
2 30  DG  n 
2 31  DT  n 
2 32  DG  n 
2 33  DG  n 
2 34  DG  n 
2 35  DT  n 
2 36  DC  n 
2 37  DT  n 
2 38  DT  n 
2 39  DC  n 
2 40  DA  n 
2 41  DT  n 
2 42  DG  n 
2 43  DA  n 
2 44  DA  n 
2 45  DG  n 
2 46  DA  n 
2 47  DC  n 
2 48  DC  n 
2 49  DC  n 
2 50  DA  n 
2 51  DC  n 
2 52  DG  n 
2 53  DC  n 
2 54  DA  n 
2 55  DT  n 
2 56  DC  n 
2 57  DC  n 
2 58  DA  n 
2 59  DC  n 
2 60  DC  n 
2 61  DG  n 
2 62  DG  n 
2 63  DT  n 
2 64  DG  n 
2 65  DT  n 
2 66  DG  n 
2 67  DA  n 
2 68  DA  n 
2 69  DG  n 
2 70  DA  n 
2 71  DC  n 
2 72  DC  n 
2 73  DC  n 
2 74  DA  n 
2 75  DC  n 
2 76  DG  n 
2 77  DC  n 
2 78  DA  n 
2 79  DT  n 
2 80  DC  n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   352 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 sgraIR 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Streptomyces griseus' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     1911 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      
;Escherichia coli 'BL21-Gold(DE3)pLysS AG'
;
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     866768 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       80 
_pdbx_entity_src_syn.organism_scientific    'Streptomyces griseus' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       1911 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE                              ? 'C3 H7 N O2'      89.093  
ARG 'L-peptide linking' y ARGININE                             ? 'C6 H15 N4 O2 1'  175.209 
ASN 'L-peptide linking' y ASPARAGINE                           ? 'C4 H8 N2 O3'     132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'                      ? 'C4 H7 N O4'      133.103 
CYS 'L-peptide linking' y CYSTEINE                             ? 'C3 H7 N O2 S'    121.158 
DA  'DNA linking'       y "2'-DEOXYADENOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O6 P' 331.222 
DC  'DNA linking'       y "2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE"  ? 'C9 H14 N3 O7 P'  307.197 
DG  'DNA linking'       y "2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE" ? 'C10 H14 N5 O7 P' 347.221 
DT  'DNA linking'       y "THYMIDINE-5'-MONOPHOSPHATE"         ? 'C10 H15 N2 O8 P' 322.208 
GLN 'L-peptide linking' y GLUTAMINE                            ? 'C5 H10 N2 O3'    146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'                      ? 'C5 H9 N O4'      147.129 
GLY 'peptide linking'   y GLYCINE                              ? 'C2 H5 N O2'      75.067  
HIS 'L-peptide linking' y HISTIDINE                            ? 'C6 H10 N3 O2 1'  156.162 
HOH non-polymer         . WATER                                ? 'H2 O'            18.015  
ILE 'L-peptide linking' y ISOLEUCINE                           ? 'C6 H13 N O2'     131.173 
LEU 'L-peptide linking' y LEUCINE                              ? 'C6 H13 N O2'     131.173 
LYS 'L-peptide linking' y LYSINE                               ? 'C6 H15 N2 O2 1'  147.195 
MET 'L-peptide linking' y METHIONINE                           ? 'C5 H11 N O2 S'   149.211 
MG  non-polymer         . 'MAGNESIUM ION'                      ? 'Mg 2'            24.305  
PHE 'L-peptide linking' y PHENYLALANINE                        ? 'C9 H11 N O2'     165.189 
PRO 'L-peptide linking' y PROLINE                              ? 'C5 H9 N O2'      115.130 
SER 'L-peptide linking' y SERINE                               ? 'C3 H7 N O3'      105.093 
THR 'L-peptide linking' y THREONINE                            ? 'C4 H9 N O3'      119.119 
TRP 'L-peptide linking' y TRYPTOPHAN                           ? 'C11 H12 N2 O2'   204.225 
TYR 'L-peptide linking' y TYROSINE                             ? 'C9 H11 N O3'     181.189 
VAL 'L-peptide linking' y VALINE                               ? 'C5 H11 N O2'     117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   PRO 2   2   2   PRO PRO A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   THR 4   4   4   THR THR A . n 
A 1 5   TYR 5   5   5   TYR TYR A . n 
A 1 6   SER 6   6   6   SER SER A . n 
A 1 7   ILE 7   7   7   ILE ILE A . n 
A 1 8   GLU 8   8   8   GLU GLU A . n 
A 1 9   ALA 9   9   9   ALA ALA A . n 
A 1 10  THR 10  10  10  THR THR A . n 
A 1 11  ARG 11  11  11  ARG ARG A . n 
A 1 12  ASN 12  12  12  ASN ASN A . n 
A 1 13  LEU 13  13  13  LEU LEU A . n 
A 1 14  ALA 14  14  14  ALA ALA A . n 
A 1 15  THR 15  15  15  THR THR A . n 
A 1 16  THR 16  16  16  THR THR A . n 
A 1 17  GLU 17  17  17  GLU GLU A . n 
A 1 18  ARG 18  18  18  ARG ARG A . n 
A 1 19  CYS 19  19  19  CYS CYS A . n 
A 1 20  ILE 20  20  20  ILE ILE A . n 
A 1 21  GLN 21  21  21  GLN GLN A . n 
A 1 22  ASP 22  22  22  ASP ASP A . n 
A 1 23  ILE 23  23  23  ILE ILE A . n 
A 1 24  ARG 24  24  24  ARG ARG A . n 
A 1 25  ASN 25  25  25  ASN ASN A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  PRO 27  27  27  PRO PRO A . n 
A 1 28  VAL 28  28  28  VAL VAL A . n 
A 1 29  ARG 29  29  29  ARG ARG A . n 
A 1 30  ASN 30  30  30  ASN ASN A . n 
A 1 31  ARG 31  31  31  ARG ARG A . n 
A 1 32  SER 32  32  32  SER SER A . n 
A 1 33  THR 33  33  33  THR THR A . n 
A 1 34  GLN 34  34  34  GLN GLN A . n 
A 1 35  PHE 35  35  35  PHE PHE A . n 
A 1 36  GLN 36  36  36  GLN GLN A . n 
A 1 37  LEU 37  37  37  LEU LEU A . n 
A 1 38  ALA 38  38  38  ALA ALA A . n 
A 1 39  GLN 39  39  39  GLN GLN A . n 
A 1 40  GLN 40  40  40  GLN GLN A . n 
A 1 41  ASN 41  41  41  ASN ASN A . n 
A 1 42  MET 42  42  42  MET MET A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  ALA 44  44  44  ALA ALA A . n 
A 1 45  TYR 45  45  45  TYR TYR A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  PHE 47  47  47  PHE PHE A . n 
A 1 48  GLY 48  48  48  GLY GLY A . n 
A 1 49  GLU 49  49  49  GLU GLU A . n 
A 1 50  VAL 50  50  50  VAL VAL A . n 
A 1 51  ILE 51  51  51  ILE ILE A . n 
A 1 52  PRO 52  52  52  PRO PRO A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  PHE 54  54  54  PHE PHE A . n 
A 1 55  ALA 55  55  55  ALA ALA A . n 
A 1 56  SER 56  56  56  SER SER A . n 
A 1 57  ALA 57  57  57  ALA ALA A . n 
A 1 58  GLY 58  58  58  GLY GLY A . n 
A 1 59  ILE 59  59  59  ILE ILE A . n 
A 1 60  ASN 60  60  60  ASN ASN A . n 
A 1 61  GLY 61  61  61  GLY GLY A . n 
A 1 62  MET 62  62  62  MET MET A . n 
A 1 63  ASP 63  63  63  ASP ASP A . n 
A 1 64  TYR 64  64  64  TYR TYR A . n 
A 1 65  ARG 65  65  65  ARG ARG A . n 
A 1 66  ASP 66  66  66  ASP ASP A . n 
A 1 67  VAL 67  67  67  VAL VAL A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  GLY 69  69  69  GLY GLY A . n 
A 1 70  ARG 70  70  70  ARG ARG A . n 
A 1 71  PRO 71  71  71  PRO PRO A . n 
A 1 72  VAL 72  72  72  VAL VAL A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  ALA 75  75  75  ALA ALA A . n 
A 1 76  VAL 76  76  76  VAL VAL A . n 
A 1 77  THR 77  77  77  THR THR A . n 
A 1 78  GLU 78  78  78  GLU GLU A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  THR 80  80  80  THR THR A . n 
A 1 81  HIS 81  81  81  HIS HIS A . n 
A 1 82  PHE 82  82  82  PHE PHE A . n 
A 1 83  PHE 83  83  83  PHE PHE A . n 
A 1 84  ARG 84  84  84  ARG ARG A . n 
A 1 85  ASP 85  85  85  ASP ASP A . n 
A 1 86  ASP 86  86  86  ASP ASP A . n 
A 1 87  PHE 87  87  87  PHE PHE A . n 
A 1 88  ARG 88  88  88  ARG ARG A . n 
A 1 89  VAL 89  89  89  VAL VAL A . n 
A 1 90  ASP 90  90  90  ASP ASP A . n 
A 1 91  SER 91  91  91  SER SER A . n 
A 1 92  ASN 92  92  92  ASN ASN A . n 
A 1 93  ALA 93  93  93  ALA ALA A . n 
A 1 94  LYS 94  94  94  LYS LYS A . n 
A 1 95  ALA 95  95  95  ALA ALA A . n 
A 1 96  LYS 96  96  96  LYS LYS A . n 
A 1 97  VAL 97  97  97  VAL VAL A . n 
A 1 98  ALA 98  98  98  ALA ALA A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 ASP 100 100 100 ASP ASP A . n 
A 1 101 ILE 101 101 101 ILE ILE A . n 
A 1 102 PHE 102 102 102 PHE PHE A . n 
A 1 103 GLU 103 103 103 GLU GLU A . n 
A 1 104 ILE 104 104 104 ILE ILE A . n 
A 1 105 VAL 105 105 105 VAL VAL A . n 
A 1 106 SER 106 106 106 SER SER A . n 
A 1 107 SER 107 107 107 SER SER A . n 
A 1 108 ALA 108 108 108 ALA ALA A . n 
A 1 109 VAL 109 109 109 VAL VAL A . n 
A 1 110 MET 110 110 110 MET MET A . n 
A 1 111 TRP 111 111 111 TRP TRP A . n 
A 1 112 ASN 112 112 112 ASN ASN A . n 
A 1 113 CYS 113 113 113 CYS CYS A . n 
A 1 114 ALA 114 114 114 ALA ALA A . n 
A 1 115 ALA 115 115 115 ALA ALA A . n 
A 1 116 ARG 116 116 116 ARG ARG A . n 
A 1 117 TRP 117 117 117 TRP TRP A . n 
A 1 118 ASN 118 118 118 ASN ASN A . n 
A 1 119 SER 119 119 119 SER SER A . n 
A 1 120 LEU 120 120 120 LEU LEU A . n 
A 1 121 MET 121 121 121 MET MET A . n 
A 1 122 VAL 122 122 122 VAL VAL A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 GLU 124 124 124 GLU GLU A . n 
A 1 125 GLY 125 125 125 GLY GLY A . n 
A 1 126 TRP 126 126 126 TRP TRP A . n 
A 1 127 ARG 127 127 127 ARG ARG A . n 
A 1 128 SER 128 128 128 SER SER A . n 
A 1 129 GLN 129 129 129 GLN GLN A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 ARG 131 131 131 ARG ARG A . n 
A 1 132 TYR 132 132 132 TYR TYR A . n 
A 1 133 SER 133 133 133 SER SER A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 PRO 135 135 135 PRO PRO A . n 
A 1 136 THR 136 136 136 THR THR A . n 
A 1 137 LEU 137 137 137 LEU LEU A . n 
A 1 138 SER 138 138 138 SER SER A . n 
A 1 139 PRO 139 139 139 PRO PRO A . n 
A 1 140 SER 140 140 140 SER SER A . n 
A 1 141 PRO 141 141 141 PRO PRO A . n 
A 1 142 ARG 142 142 142 ARG ARG A . n 
A 1 143 ARG 143 143 143 ARG ARG A . n 
A 1 144 GLN 144 144 144 GLN GLN A . n 
A 1 145 VAL 145 145 145 VAL VAL A . n 
A 1 146 ALA 146 146 146 ALA ALA A . n 
A 1 147 VAL 147 147 147 VAL VAL A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 ASN 149 149 149 ASN ASN A . n 
A 1 150 LEU 150 150 150 LEU LEU A . n 
A 1 151 PRO 151 151 151 PRO PRO A . n 
A 1 152 ARG 152 152 152 ARG ARG A . n 
A 1 153 SER 153 153 153 SER SER A . n 
A 1 154 PHE 154 154 154 PHE PHE A . n 
A 1 155 ASP 155 155 155 ASP ASP A . n 
A 1 156 TRP 156 156 156 TRP TRP A . n 
A 1 157 VAL 157 157 157 VAL VAL A . n 
A 1 158 SER 158 158 158 SER SER A . n 
A 1 159 LEU 159 159 159 LEU LEU A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 VAL 161 161 161 VAL VAL A . n 
A 1 162 PRO 162 162 162 PRO PRO A . n 
A 1 163 GLU 163 163 163 GLU GLU A . n 
A 1 164 SER 164 164 164 SER SER A . n 
A 1 165 GLN 165 165 165 GLN GLN A . n 
A 1 166 GLU 166 166 166 GLU GLU A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 ILE 168 168 168 ILE ILE A . n 
A 1 169 GLU 169 169 169 GLU GLU A . n 
A 1 170 GLU 170 170 170 GLU GLU A . n 
A 1 171 PHE 171 171 171 PHE PHE A . n 
A 1 172 ARG 172 172 172 ARG ARG A . n 
A 1 173 ALA 173 173 173 ALA ALA A . n 
A 1 174 GLY 174 174 174 GLY GLY A . n 
A 1 175 LEU 175 175 175 LEU LEU A . n 
A 1 176 ARG 176 176 176 ARG ARG A . n 
A 1 177 LYS 177 177 177 LYS LYS A . n 
A 1 178 ASP 178 178 178 ASP ASP A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 GLY 181 181 181 GLY GLY A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 THR 184 184 184 THR THR A . n 
A 1 185 SER 185 185 185 SER SER A . n 
A 1 186 THR 186 186 186 THR THR A . n 
A 1 187 PRO 187 187 187 PRO PRO A . n 
A 1 188 ASP 188 188 188 ASP ASP A . n 
A 1 189 LEU 189 189 189 LEU LEU A . n 
A 1 190 ALA 190 190 190 ALA ALA A . n 
A 1 191 VAL 191 191 191 VAL VAL A . n 
A 1 192 VAL 192 192 192 VAL VAL A . n 
A 1 193 VAL 193 193 193 VAL VAL A . n 
A 1 194 LEU 194 194 194 LEU LEU A . n 
A 1 195 PRO 195 195 195 PRO PRO A . n 
A 1 196 GLU 196 196 196 GLU GLU A . n 
A 1 197 GLU 197 197 197 GLU GLU A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 GLN 199 199 199 GLN GLN A . n 
A 1 200 ASN 200 200 200 ASN ASN A . n 
A 1 201 ASP 201 201 201 ASP ASP A . n 
A 1 202 GLU 202 202 202 GLU GLU A . n 
A 1 203 MET 203 203 203 MET MET A . n 
A 1 204 TRP 204 204 204 TRP TRP A . n 
A 1 205 ARG 205 205 205 ARG ARG A . n 
A 1 206 GLU 206 206 206 GLU GLU A . n 
A 1 207 GLU 207 207 207 GLU GLU A . n 
A 1 208 ILE 208 208 208 ILE ILE A . n 
A 1 209 ALA 209 209 209 ALA ALA A . n 
A 1 210 GLY 210 210 210 GLY GLY A . n 
A 1 211 LEU 211 211 211 LEU LEU A . n 
A 1 212 THR 212 212 212 THR THR A . n 
A 1 213 ARG 213 213 213 ARG ARG A . n 
A 1 214 PRO 214 214 214 PRO PRO A . n 
A 1 215 ASN 215 215 215 ASN ASN A . n 
A 1 216 GLN 216 216 216 GLN GLN A . n 
A 1 217 ILE 217 217 217 ILE ILE A . n 
A 1 218 LEU 218 218 218 LEU LEU A . n 
A 1 219 LEU 219 219 219 LEU LEU A . n 
A 1 220 SER 220 220 220 SER SER A . n 
A 1 221 GLY 221 221 221 GLY GLY A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 TYR 223 223 223 TYR TYR A . n 
A 1 224 GLN 224 224 224 GLN GLN A . n 
A 1 225 ARG 225 225 225 ARG ARG A . n 
A 1 226 LEU 226 226 226 LEU LEU A . n 
A 1 227 GLN 227 227 227 GLN GLN A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ARG 229 229 229 ARG ARG A . n 
A 1 230 VAL 230 230 230 VAL VAL A . n 
A 1 231 GLN 231 231 231 GLN GLN A . n 
A 1 232 PRO 232 232 232 PRO PRO A . n 
A 1 233 GLY 233 233 233 GLY GLY A . n 
A 1 234 GLU 234 234 234 GLU GLU A . n 
A 1 235 ILE 235 235 235 ILE ILE A . n 
A 1 236 SER 236 236 236 SER SER A . n 
A 1 237 LEU 237 237 237 LEU LEU A . n 
A 1 238 ALA 238 238 238 ALA ALA A . n 
A 1 239 VAL 239 239 239 VAL VAL A . n 
A 1 240 ALA 240 240 240 ALA ALA A . n 
A 1 241 PHE 241 241 241 PHE PHE A . n 
A 1 242 ALA 242 242 242 ALA ALA A . n 
A 1 243 ARG 243 243 243 ARG ARG A . n 
A 1 244 SER 244 244 244 SER SER A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 ARG 246 246 246 ARG ARG A . n 
A 1 247 SER 247 247 247 SER SER A . n 
A 1 248 ASP 248 248 248 ASP ASP A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 LEU 250 250 250 LEU LEU A . n 
A 1 251 TYR 251 251 251 TYR TYR A . n 
A 1 252 GLN 252 252 252 GLN GLN A . n 
A 1 253 PRO 253 253 253 PRO PRO A . n 
A 1 254 LEU 254 254 254 LEU LEU A . n 
A 1 255 TYR 255 255 255 TYR TYR A . n 
A 1 256 GLU 256 256 256 GLU GLU A . n 
A 1 257 ALA 257 257 257 ALA ALA A . n 
A 1 258 ASN 258 258 258 ASN ASN A . n 
A 1 259 VAL 259 259 259 VAL VAL A . n 
A 1 260 MET 260 260 260 MET MET A . n 
A 1 261 GLN 261 261 261 GLN GLN A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 LEU 264 264 264 LEU LEU A . n 
A 1 265 GLU 265 265 265 GLU GLU A . n 
A 1 266 GLY 266 266 266 GLY GLY A . n 
A 1 267 LYS 267 267 267 LYS LYS A . n 
A 1 268 LEU 268 268 268 LEU LEU A . n 
A 1 269 GLY 269 269 269 GLY GLY A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 PRO 271 271 271 PRO PRO A . n 
A 1 272 LYS 272 272 272 LYS LYS A . n 
A 1 273 VAL 273 273 273 VAL VAL A . n 
A 1 274 GLU 274 274 274 GLU GLU A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 GLU 276 276 276 GLU GLU A . n 
A 1 277 VAL 277 277 277 VAL VAL A . n 
A 1 278 HIS 278 278 278 HIS HIS A . n 
A 1 279 THR 279 279 279 THR THR A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 ALA 281 281 281 ALA ALA A . n 
A 1 282 PRO 282 282 282 PRO PRO A . n 
A 1 283 GLU 283 283 283 GLU GLU A . n 
A 1 284 GLY 284 284 284 GLY GLY A . n 
A 1 285 THR 285 285 285 THR THR A . n 
A 1 286 ASN 286 286 286 ASN ASN A . n 
A 1 287 ALA 287 287 287 ALA ALA A . n 
A 1 288 PHE 288 288 288 PHE PHE A . n 
A 1 289 VAL 289 289 289 VAL VAL A . n 
A 1 290 THR 290 290 290 THR THR A . n 
A 1 291 TYR 291 291 291 TYR TYR A . n 
A 1 292 GLU 292 292 292 GLU GLU A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 ALA 294 294 294 ALA ALA A . n 
A 1 295 SER 295 295 295 SER SER A . n 
A 1 296 LEU 296 296 296 LEU LEU A . n 
A 1 297 TYR 297 297 297 TYR TYR A . n 
A 1 298 GLY 298 298 298 GLY GLY A . n 
A 1 299 LEU 299 299 299 LEU LEU A . n 
A 1 300 ALA 300 300 300 ALA ALA A . n 
A 1 301 GLU 301 301 301 GLU GLU A . n 
A 1 302 GLY 302 302 302 GLY GLY A . n 
A 1 303 ARG 303 303 303 ARG ARG A . n 
A 1 304 SER 304 304 304 SER SER A . n 
A 1 305 ALA 305 305 305 ALA ALA A . n 
A 1 306 VAL 306 306 306 VAL VAL A . n 
A 1 307 HIS 307 307 307 HIS HIS A . n 
A 1 308 ARG 308 308 308 ARG ARG A . n 
A 1 309 ALA 309 309 309 ALA ALA A . n 
A 1 310 ILE 310 310 310 ILE ILE A . n 
A 1 311 ARG 311 311 311 ARG ARG A . n 
A 1 312 GLU 312 312 312 GLU GLU A . n 
A 1 313 LEU 313 313 313 LEU LEU A . n 
A 1 314 TYR 314 314 314 TYR TYR A . n 
A 1 315 VAL 315 315 315 VAL VAL A . n 
A 1 316 PRO 316 316 316 PRO PRO A . n 
A 1 317 PRO 317 317 317 PRO PRO A . n 
A 1 318 THR 318 318 318 THR THR A . n 
A 1 319 ALA 319 319 319 ALA ALA A . n 
A 1 320 ALA 320 320 320 ALA ALA A . n 
A 1 321 ASP 321 321 321 ASP ASP A . n 
A 1 322 LEU 322 322 322 LEU LEU A . n 
A 1 323 ALA 323 323 323 ALA ALA A . n 
A 1 324 ARG 324 324 324 ARG ARG A . n 
A 1 325 ARG 325 325 325 ARG ARG A . n 
A 1 326 PHE 326 326 326 PHE PHE A . n 
A 1 327 PHE 327 327 327 PHE PHE A . n 
A 1 328 ALA 328 328 328 ALA ALA A . n 
A 1 329 PHE 329 329 329 PHE PHE A . n 
A 1 330 LEU 330 330 330 LEU LEU A . n 
A 1 331 ASN 331 331 331 ASN ASN A . n 
A 1 332 GLU 332 332 332 GLU GLU A . n 
A 1 333 ARG 333 333 333 ARG ARG A . n 
A 1 334 MET 334 334 334 MET MET A . n 
A 1 335 GLU 335 335 335 GLU GLU A . n 
A 1 336 LYS 336 336 336 LYS LYS A . n 
A 1 337 VAL 337 337 337 VAL VAL A . n 
A 1 338 ASN 338 338 338 ASN ASN A . n 
A 1 339 GLY 339 339 339 GLY GLY A . n 
A 1 340 GLU 340 340 ?   ?   ?   A . n 
A 1 341 ASN 341 341 ?   ?   ?   A . n 
A 1 342 LEU 342 342 ?   ?   ?   A . n 
A 1 343 TYR 343 343 ?   ?   ?   A . n 
A 1 344 PHE 344 344 ?   ?   ?   A . n 
A 1 345 GLN 345 345 ?   ?   ?   A . n 
A 1 346 SER 346 346 ?   ?   ?   A . n 
A 1 347 HIS 347 347 ?   ?   ?   A . n 
A 1 348 HIS 348 348 ?   ?   ?   A . n 
A 1 349 HIS 349 349 ?   ?   ?   A . n 
A 1 350 HIS 350 350 ?   ?   ?   A . n 
A 1 351 HIS 351 351 ?   ?   ?   A . n 
A 1 352 HIS 352 352 ?   ?   ?   A . n 
B 2 1   DG  1   -6  ?   ?   ?   C . n 
B 2 2   DA  2   -5  ?   ?   ?   C . n 
B 2 3   DT  3   -4  ?   ?   ?   C . n 
B 2 4   DG  4   -3  ?   ?   ?   C . n 
B 2 5   DC  5   -2  ?   ?   ?   C . n 
B 2 6   DG  6   -1  ?   ?   ?   C . n 
B 2 7   DT  7   0   ?   ?   ?   C . n 
B 2 8   DG  8   1   ?   ?   ?   C . n 
B 2 9   DG  9   2   2   DG  DG  C . n 
B 2 10  DG  10  3   3   DG  DG  C . n 
B 2 11  DT  11  4   4   DT  DT  C . n 
B 2 12  DC  12  5   5   DC  DC  C . n 
B 2 13  DT  13  6   6   DT  DT  C . n 
B 2 14  DT  14  7   7   DT  DT  C . n 
B 2 15  DC  15  8   8   DC  DC  C . n 
B 2 16  DA  16  9   9   DA  DA  C . n 
B 2 17  DC  17  10  10  DC  DC  C . n 
B 2 18  DA  18  11  11  DA  DA  C . n 
B 2 19  DC  19  12  12  DC  DC  C . n 
B 2 20  DC  20  13  13  DC  DC  C . n 
B 2 21  DG  21  14  14  DG  DG  C . n 
B 2 22  DG  22  15  15  DG  DG  C . n 
B 2 23  DT  23  16  16  DT  DT  C . n 
B 2 24  DG  24  17  17  DG  DG  C . n 
B 2 25  DG  25  18  18  DG  DG  C . n 
B 2 26  DA  26  19  19  DA  DA  C . n 
B 2 27  DT  27  20  20  DT  DT  C . n 
B 2 28  DG  28  21  21  DG  DG  C . n 
B 2 29  DC  29  22  22  DC  DC  C . n 
B 2 30  DG  30  23  23  DG  DG  C . n 
B 2 31  DT  31  24  24  DT  DT  C . n 
B 2 32  DG  32  25  25  DG  DG  C . n 
B 2 33  DG  33  26  26  DG  DG  C . n 
B 2 34  DG  34  27  ?   ?   ?   C . n 
B 2 35  DT  35  28  ?   ?   ?   C . n 
B 2 36  DC  36  29  ?   ?   ?   C . n 
B 2 37  DT  37  30  ?   ?   ?   C . n 
B 2 38  DT  38  31  ?   ?   ?   C . n 
B 2 39  DC  39  32  ?   ?   ?   C . n 
B 2 40  DA  40  33  ?   ?   ?   C . n 
B 2 41  DT  41  34  ?   ?   ?   C . n 
B 2 42  DG  42  35  ?   ?   ?   C . n 
B 2 43  DA  43  36  ?   ?   ?   C . n 
B 2 44  DA  44  37  ?   ?   ?   C . n 
B 2 45  DG  45  38  ?   ?   ?   C . n 
B 2 46  DA  46  39  ?   ?   ?   C . n 
B 2 47  DC  47  40  ?   ?   ?   C . n 
B 2 48  DC  48  41  ?   ?   ?   C . n 
B 2 49  DC  49  42  ?   ?   ?   C . n 
B 2 50  DA  50  43  ?   ?   ?   C . n 
B 2 51  DC  51  44  ?   ?   ?   C . n 
B 2 52  DG  52  45  ?   ?   ?   C . n 
B 2 53  DC  53  46  ?   ?   ?   C . n 
B 2 54  DA  54  47  ?   ?   ?   C . n 
B 2 55  DT  55  48  ?   ?   ?   C . n 
B 2 56  DC  56  49  ?   ?   ?   C . n 
B 2 57  DC  57  50  ?   ?   ?   C . n 
B 2 58  DA  58  51  ?   ?   ?   C . n 
B 2 59  DC  59  52  ?   ?   ?   C . n 
B 2 60  DC  60  53  ?   ?   ?   C . n 
B 2 61  DG  61  54  ?   ?   ?   C . n 
B 2 62  DG  62  55  ?   ?   ?   C . n 
B 2 63  DT  63  56  ?   ?   ?   C . n 
B 2 64  DG  64  57  ?   ?   ?   C . n 
B 2 65  DT  65  58  ?   ?   ?   C . n 
B 2 66  DG  66  59  ?   ?   ?   C . n 
B 2 67  DA  67  60  ?   ?   ?   C . n 
B 2 68  DA  68  61  ?   ?   ?   C . n 
B 2 69  DG  69  62  ?   ?   ?   C . n 
B 2 70  DA  70  63  ?   ?   ?   C . n 
B 2 71  DC  71  64  ?   ?   ?   C . n 
B 2 72  DC  72  65  ?   ?   ?   C . n 
B 2 73  DC  73  66  ?   ?   ?   C . n 
B 2 74  DA  74  67  ?   ?   ?   C . n 
B 2 75  DC  75  68  ?   ?   ?   C . n 
B 2 76  DG  76  69  ?   ?   ?   C . n 
B 2 77  DC  77  70  ?   ?   ?   C . n 
B 2 78  DA  78  71  ?   ?   ?   C . n 
B 2 79  DT  79  72  ?   ?   ?   C . n 
B 2 80  DC  80  73  ?   ?   ?   C . n 
C 1 1   MET 1   1   ?   ?   ?   B . n 
C 1 2   PRO 2   2   2   PRO PRO B . n 
C 1 3   PHE 3   3   3   PHE PHE B . n 
C 1 4   THR 4   4   4   THR THR B . n 
C 1 5   TYR 5   5   5   TYR TYR B . n 
C 1 6   SER 6   6   6   SER SER B . n 
C 1 7   ILE 7   7   7   ILE ILE B . n 
C 1 8   GLU 8   8   8   GLU GLU B . n 
C 1 9   ALA 9   9   9   ALA ALA B . n 
C 1 10  THR 10  10  10  THR THR B . n 
C 1 11  ARG 11  11  11  ARG ARG B . n 
C 1 12  ASN 12  12  12  ASN ASN B . n 
C 1 13  LEU 13  13  13  LEU LEU B . n 
C 1 14  ALA 14  14  14  ALA ALA B . n 
C 1 15  THR 15  15  15  THR THR B . n 
C 1 16  THR 16  16  16  THR THR B . n 
C 1 17  GLU 17  17  17  GLU GLU B . n 
C 1 18  ARG 18  18  18  ARG ARG B . n 
C 1 19  CYS 19  19  19  CYS CYS B . n 
C 1 20  ILE 20  20  20  ILE ILE B . n 
C 1 21  GLN 21  21  21  GLN GLN B . n 
C 1 22  ASP 22  22  22  ASP ASP B . n 
C 1 23  ILE 23  23  23  ILE ILE B . n 
C 1 24  ARG 24  24  24  ARG ARG B . n 
C 1 25  ASN 25  25  25  ASN ASN B . n 
C 1 26  ALA 26  26  26  ALA ALA B . n 
C 1 27  PRO 27  27  27  PRO PRO B . n 
C 1 28  VAL 28  28  28  VAL VAL B . n 
C 1 29  ARG 29  29  29  ARG ARG B . n 
C 1 30  ASN 30  30  30  ASN ASN B . n 
C 1 31  ARG 31  31  31  ARG ARG B . n 
C 1 32  SER 32  32  32  SER SER B . n 
C 1 33  THR 33  33  33  THR THR B . n 
C 1 34  GLN 34  34  34  GLN GLN B . n 
C 1 35  PHE 35  35  35  PHE PHE B . n 
C 1 36  GLN 36  36  36  GLN GLN B . n 
C 1 37  LEU 37  37  37  LEU LEU B . n 
C 1 38  ALA 38  38  38  ALA ALA B . n 
C 1 39  GLN 39  39  39  GLN GLN B . n 
C 1 40  GLN 40  40  40  GLN GLN B . n 
C 1 41  ASN 41  41  41  ASN ASN B . n 
C 1 42  MET 42  42  42  MET MET B . n 
C 1 43  LEU 43  43  43  LEU LEU B . n 
C 1 44  ALA 44  44  44  ALA ALA B . n 
C 1 45  TYR 45  45  45  TYR TYR B . n 
C 1 46  THR 46  46  46  THR THR B . n 
C 1 47  PHE 47  47  47  PHE PHE B . n 
C 1 48  GLY 48  48  48  GLY GLY B . n 
C 1 49  GLU 49  49  49  GLU GLU B . n 
C 1 50  VAL 50  50  50  VAL VAL B . n 
C 1 51  ILE 51  51  51  ILE ILE B . n 
C 1 52  PRO 52  52  52  PRO PRO B . n 
C 1 53  GLY 53  53  53  GLY GLY B . n 
C 1 54  PHE 54  54  54  PHE PHE B . n 
C 1 55  ALA 55  55  55  ALA ALA B . n 
C 1 56  SER 56  56  56  SER SER B . n 
C 1 57  ALA 57  57  57  ALA ALA B . n 
C 1 58  GLY 58  58  58  GLY GLY B . n 
C 1 59  ILE 59  59  59  ILE ILE B . n 
C 1 60  ASN 60  60  60  ASN ASN B . n 
C 1 61  GLY 61  61  61  GLY GLY B . n 
C 1 62  MET 62  62  62  MET MET B . n 
C 1 63  ASP 63  63  63  ASP ASP B . n 
C 1 64  TYR 64  64  64  TYR TYR B . n 
C 1 65  ARG 65  65  65  ARG ARG B . n 
C 1 66  ASP 66  66  66  ASP ASP B . n 
C 1 67  VAL 67  67  67  VAL VAL B . n 
C 1 68  ILE 68  68  68  ILE ILE B . n 
C 1 69  GLY 69  69  69  GLY GLY B . n 
C 1 70  ARG 70  70  70  ARG ARG B . n 
C 1 71  PRO 71  71  71  PRO PRO B . n 
C 1 72  VAL 72  72  72  VAL VAL B . n 
C 1 73  GLU 73  73  73  GLU GLU B . n 
C 1 74  ASN 74  74  74  ASN ASN B . n 
C 1 75  ALA 75  75  75  ALA ALA B . n 
C 1 76  VAL 76  76  76  VAL VAL B . n 
C 1 77  THR 77  77  77  THR THR B . n 
C 1 78  GLU 78  78  78  GLU GLU B . n 
C 1 79  GLY 79  79  79  GLY GLY B . n 
C 1 80  THR 80  80  80  THR THR B . n 
C 1 81  HIS 81  81  81  HIS HIS B . n 
C 1 82  PHE 82  82  82  PHE PHE B . n 
C 1 83  PHE 83  83  83  PHE PHE B . n 
C 1 84  ARG 84  84  84  ARG ARG B . n 
C 1 85  ASP 85  85  85  ASP ASP B . n 
C 1 86  ASP 86  86  86  ASP ASP B . n 
C 1 87  PHE 87  87  87  PHE PHE B . n 
C 1 88  ARG 88  88  88  ARG ARG B . n 
C 1 89  VAL 89  89  89  VAL VAL B . n 
C 1 90  ASP 90  90  90  ASP ASP B . n 
C 1 91  SER 91  91  91  SER SER B . n 
C 1 92  ASN 92  92  92  ASN ASN B . n 
C 1 93  ALA 93  93  93  ALA ALA B . n 
C 1 94  LYS 94  94  94  LYS LYS B . n 
C 1 95  ALA 95  95  95  ALA ALA B . n 
C 1 96  LYS 96  96  96  LYS LYS B . n 
C 1 97  VAL 97  97  97  VAL VAL B . n 
C 1 98  ALA 98  98  98  ALA ALA B . n 
C 1 99  GLY 99  99  99  GLY GLY B . n 
C 1 100 ASP 100 100 100 ASP ASP B . n 
C 1 101 ILE 101 101 101 ILE ILE B . n 
C 1 102 PHE 102 102 102 PHE PHE B . n 
C 1 103 GLU 103 103 103 GLU GLU B . n 
C 1 104 ILE 104 104 104 ILE ILE B . n 
C 1 105 VAL 105 105 105 VAL VAL B . n 
C 1 106 SER 106 106 106 SER SER B . n 
C 1 107 SER 107 107 107 SER SER B . n 
C 1 108 ALA 108 108 108 ALA ALA B . n 
C 1 109 VAL 109 109 109 VAL VAL B . n 
C 1 110 MET 110 110 110 MET MET B . n 
C 1 111 TRP 111 111 111 TRP TRP B . n 
C 1 112 ASN 112 112 112 ASN ASN B . n 
C 1 113 CYS 113 113 113 CYS CYS B . n 
C 1 114 ALA 114 114 114 ALA ALA B . n 
C 1 115 ALA 115 115 115 ALA ALA B . n 
C 1 116 ARG 116 116 116 ARG ARG B . n 
C 1 117 TRP 117 117 117 TRP TRP B . n 
C 1 118 ASN 118 118 118 ASN ASN B . n 
C 1 119 SER 119 119 119 SER SER B . n 
C 1 120 LEU 120 120 120 LEU LEU B . n 
C 1 121 MET 121 121 121 MET MET B . n 
C 1 122 VAL 122 122 122 VAL VAL B . n 
C 1 123 GLY 123 123 123 GLY GLY B . n 
C 1 124 GLU 124 124 124 GLU GLU B . n 
C 1 125 GLY 125 125 125 GLY GLY B . n 
C 1 126 TRP 126 126 126 TRP TRP B . n 
C 1 127 ARG 127 127 127 ARG ARG B . n 
C 1 128 SER 128 128 128 SER SER B . n 
C 1 129 GLN 129 129 129 GLN GLN B . n 
C 1 130 PRO 130 130 130 PRO PRO B . n 
C 1 131 ARG 131 131 131 ARG ARG B . n 
C 1 132 TYR 132 132 132 TYR TYR B . n 
C 1 133 SER 133 133 133 SER SER B . n 
C 1 134 ARG 134 134 134 ARG ARG B . n 
C 1 135 PRO 135 135 135 PRO PRO B . n 
C 1 136 THR 136 136 136 THR THR B . n 
C 1 137 LEU 137 137 137 LEU LEU B . n 
C 1 138 SER 138 138 138 SER SER B . n 
C 1 139 PRO 139 139 139 PRO PRO B . n 
C 1 140 SER 140 140 140 SER SER B . n 
C 1 141 PRO 141 141 141 PRO PRO B . n 
C 1 142 ARG 142 142 142 ARG ARG B . n 
C 1 143 ARG 143 143 143 ARG ARG B . n 
C 1 144 GLN 144 144 144 GLN GLN B . n 
C 1 145 VAL 145 145 145 VAL VAL B . n 
C 1 146 ALA 146 146 146 ALA ALA B . n 
C 1 147 VAL 147 147 147 VAL VAL B . n 
C 1 148 LEU 148 148 148 LEU LEU B . n 
C 1 149 ASN 149 149 149 ASN ASN B . n 
C 1 150 LEU 150 150 150 LEU LEU B . n 
C 1 151 PRO 151 151 151 PRO PRO B . n 
C 1 152 ARG 152 152 152 ARG ARG B . n 
C 1 153 SER 153 153 153 SER SER B . n 
C 1 154 PHE 154 154 154 PHE PHE B . n 
C 1 155 ASP 155 155 155 ASP ASP B . n 
C 1 156 TRP 156 156 156 TRP TRP B . n 
C 1 157 VAL 157 157 157 VAL VAL B . n 
C 1 158 SER 158 158 158 SER SER B . n 
C 1 159 LEU 159 159 159 LEU LEU B . n 
C 1 160 LEU 160 160 160 LEU LEU B . n 
C 1 161 VAL 161 161 161 VAL VAL B . n 
C 1 162 PRO 162 162 162 PRO PRO B . n 
C 1 163 GLU 163 163 163 GLU GLU B . n 
C 1 164 SER 164 164 164 SER SER B . n 
C 1 165 GLN 165 165 165 GLN GLN B . n 
C 1 166 GLU 166 166 166 GLU GLU B . n 
C 1 167 VAL 167 167 167 VAL VAL B . n 
C 1 168 ILE 168 168 168 ILE ILE B . n 
C 1 169 GLU 169 169 169 GLU GLU B . n 
C 1 170 GLU 170 170 170 GLU GLU B . n 
C 1 171 PHE 171 171 171 PHE PHE B . n 
C 1 172 ARG 172 172 172 ARG ARG B . n 
C 1 173 ALA 173 173 173 ALA ALA B . n 
C 1 174 GLY 174 174 174 GLY GLY B . n 
C 1 175 LEU 175 175 175 LEU LEU B . n 
C 1 176 ARG 176 176 176 ARG ARG B . n 
C 1 177 LYS 177 177 177 LYS LYS B . n 
C 1 178 ASP 178 178 178 ASP ASP B . n 
C 1 179 GLY 179 179 179 GLY GLY B . n 
C 1 180 LEU 180 180 180 LEU LEU B . n 
C 1 181 GLY 181 181 181 GLY GLY B . n 
C 1 182 LEU 182 182 182 LEU LEU B . n 
C 1 183 PRO 183 183 183 PRO PRO B . n 
C 1 184 THR 184 184 184 THR THR B . n 
C 1 185 SER 185 185 185 SER SER B . n 
C 1 186 THR 186 186 186 THR THR B . n 
C 1 187 PRO 187 187 187 PRO PRO B . n 
C 1 188 ASP 188 188 188 ASP ASP B . n 
C 1 189 LEU 189 189 189 LEU LEU B . n 
C 1 190 ALA 190 190 190 ALA ALA B . n 
C 1 191 VAL 191 191 191 VAL VAL B . n 
C 1 192 VAL 192 192 192 VAL VAL B . n 
C 1 193 VAL 193 193 193 VAL VAL B . n 
C 1 194 LEU 194 194 194 LEU LEU B . n 
C 1 195 PRO 195 195 195 PRO PRO B . n 
C 1 196 GLU 196 196 196 GLU GLU B . n 
C 1 197 GLU 197 197 197 GLU GLU B . n 
C 1 198 PHE 198 198 198 PHE PHE B . n 
C 1 199 GLN 199 199 199 GLN GLN B . n 
C 1 200 ASN 200 200 200 ASN ASN B . n 
C 1 201 ASP 201 201 201 ASP ASP B . n 
C 1 202 GLU 202 202 202 GLU GLU B . n 
C 1 203 MET 203 203 203 MET MET B . n 
C 1 204 TRP 204 204 204 TRP TRP B . n 
C 1 205 ARG 205 205 205 ARG ARG B . n 
C 1 206 GLU 206 206 206 GLU GLU B . n 
C 1 207 GLU 207 207 207 GLU GLU B . n 
C 1 208 ILE 208 208 208 ILE ILE B . n 
C 1 209 ALA 209 209 209 ALA ALA B . n 
C 1 210 GLY 210 210 210 GLY GLY B . n 
C 1 211 LEU 211 211 211 LEU LEU B . n 
C 1 212 THR 212 212 212 THR THR B . n 
C 1 213 ARG 213 213 213 ARG ARG B . n 
C 1 214 PRO 214 214 214 PRO PRO B . n 
C 1 215 ASN 215 215 215 ASN ASN B . n 
C 1 216 GLN 216 216 216 GLN GLN B . n 
C 1 217 ILE 217 217 217 ILE ILE B . n 
C 1 218 LEU 218 218 218 LEU LEU B . n 
C 1 219 LEU 219 219 219 LEU LEU B . n 
C 1 220 SER 220 220 220 SER SER B . n 
C 1 221 GLY 221 221 221 GLY GLY B . n 
C 1 222 ALA 222 222 222 ALA ALA B . n 
C 1 223 TYR 223 223 223 TYR TYR B . n 
C 1 224 GLN 224 224 224 GLN GLN B . n 
C 1 225 ARG 225 225 225 ARG ARG B . n 
C 1 226 LEU 226 226 226 LEU LEU B . n 
C 1 227 GLN 227 227 227 GLN GLN B . n 
C 1 228 GLY 228 228 228 GLY GLY B . n 
C 1 229 ARG 229 229 229 ARG ARG B . n 
C 1 230 VAL 230 230 230 VAL VAL B . n 
C 1 231 GLN 231 231 231 GLN GLN B . n 
C 1 232 PRO 232 232 232 PRO PRO B . n 
C 1 233 GLY 233 233 233 GLY GLY B . n 
C 1 234 GLU 234 234 234 GLU GLU B . n 
C 1 235 ILE 235 235 235 ILE ILE B . n 
C 1 236 SER 236 236 236 SER SER B . n 
C 1 237 LEU 237 237 237 LEU LEU B . n 
C 1 238 ALA 238 238 238 ALA ALA B . n 
C 1 239 VAL 239 239 239 VAL VAL B . n 
C 1 240 ALA 240 240 240 ALA ALA B . n 
C 1 241 PHE 241 241 241 PHE PHE B . n 
C 1 242 ALA 242 242 242 ALA ALA B . n 
C 1 243 ARG 243 243 243 ARG ARG B . n 
C 1 244 SER 244 244 244 SER SER B . n 
C 1 245 LEU 245 245 245 LEU LEU B . n 
C 1 246 ARG 246 246 246 ARG ARG B . n 
C 1 247 SER 247 247 247 SER SER B . n 
C 1 248 ASP 248 248 248 ASP ASP B . n 
C 1 249 ARG 249 249 249 ARG ARG B . n 
C 1 250 LEU 250 250 250 LEU LEU B . n 
C 1 251 TYR 251 251 251 TYR TYR B . n 
C 1 252 GLN 252 252 252 GLN GLN B . n 
C 1 253 PRO 253 253 253 PRO PRO B . n 
C 1 254 LEU 254 254 254 LEU LEU B . n 
C 1 255 TYR 255 255 255 TYR TYR B . n 
C 1 256 GLU 256 256 256 GLU GLU B . n 
C 1 257 ALA 257 257 257 ALA ALA B . n 
C 1 258 ASN 258 258 258 ASN ASN B . n 
C 1 259 VAL 259 259 259 VAL VAL B . n 
C 1 260 MET 260 260 260 MET MET B . n 
C 1 261 GLN 261 261 261 GLN GLN B . n 
C 1 262 LEU 262 262 262 LEU LEU B . n 
C 1 263 LEU 263 263 263 LEU LEU B . n 
C 1 264 LEU 264 264 264 LEU LEU B . n 
C 1 265 GLU 265 265 265 GLU GLU B . n 
C 1 266 GLY 266 266 266 GLY GLY B . n 
C 1 267 LYS 267 267 267 LYS LYS B . n 
C 1 268 LEU 268 268 268 LEU LEU B . n 
C 1 269 GLY 269 269 269 GLY GLY B . n 
C 1 270 ALA 270 270 270 ALA ALA B . n 
C 1 271 PRO 271 271 271 PRO PRO B . n 
C 1 272 LYS 272 272 272 LYS LYS B . n 
C 1 273 VAL 273 273 273 VAL VAL B . n 
C 1 274 GLU 274 274 274 GLU GLU B . n 
C 1 275 PHE 275 275 275 PHE PHE B . n 
C 1 276 GLU 276 276 276 GLU GLU B . n 
C 1 277 VAL 277 277 277 VAL VAL B . n 
C 1 278 HIS 278 278 278 HIS HIS B . n 
C 1 279 THR 279 279 279 THR THR B . n 
C 1 280 LEU 280 280 280 LEU LEU B . n 
C 1 281 ALA 281 281 281 ALA ALA B . n 
C 1 282 PRO 282 282 282 PRO PRO B . n 
C 1 283 GLU 283 283 283 GLU GLU B . n 
C 1 284 GLY 284 284 284 GLY GLY B . n 
C 1 285 THR 285 285 285 THR THR B . n 
C 1 286 ASN 286 286 286 ASN ASN B . n 
C 1 287 ALA 287 287 287 ALA ALA B . n 
C 1 288 PHE 288 288 288 PHE PHE B . n 
C 1 289 VAL 289 289 289 VAL VAL B . n 
C 1 290 THR 290 290 290 THR THR B . n 
C 1 291 TYR 291 291 291 TYR TYR B . n 
C 1 292 GLU 292 292 292 GLU GLU B . n 
C 1 293 ALA 293 293 293 ALA ALA B . n 
C 1 294 ALA 294 294 294 ALA ALA B . n 
C 1 295 SER 295 295 295 SER SER B . n 
C 1 296 LEU 296 296 296 LEU LEU B . n 
C 1 297 TYR 297 297 297 TYR TYR B . n 
C 1 298 GLY 298 298 298 GLY GLY B . n 
C 1 299 LEU 299 299 299 LEU LEU B . n 
C 1 300 ALA 300 300 ?   ?   ?   B . n 
C 1 301 GLU 301 301 ?   ?   ?   B . n 
C 1 302 GLY 302 302 ?   ?   ?   B . n 
C 1 303 ARG 303 303 ?   ?   ?   B . n 
C 1 304 SER 304 304 304 SER SER B . n 
C 1 305 ALA 305 305 305 ALA ALA B . n 
C 1 306 VAL 306 306 306 VAL VAL B . n 
C 1 307 HIS 307 307 307 HIS HIS B . n 
C 1 308 ARG 308 308 308 ARG ARG B . n 
C 1 309 ALA 309 309 309 ALA ALA B . n 
C 1 310 ILE 310 310 310 ILE ILE B . n 
C 1 311 ARG 311 311 311 ARG ARG B . n 
C 1 312 GLU 312 312 312 GLU GLU B . n 
C 1 313 LEU 313 313 313 LEU LEU B . n 
C 1 314 TYR 314 314 314 TYR TYR B . n 
C 1 315 VAL 315 315 315 VAL VAL B . n 
C 1 316 PRO 316 316 316 PRO PRO B . n 
C 1 317 PRO 317 317 317 PRO PRO B . n 
C 1 318 THR 318 318 318 THR THR B . n 
C 1 319 ALA 319 319 319 ALA ALA B . n 
C 1 320 ALA 320 320 320 ALA ALA B . n 
C 1 321 ASP 321 321 321 ASP ASP B . n 
C 1 322 LEU 322 322 322 LEU LEU B . n 
C 1 323 ALA 323 323 323 ALA ALA B . n 
C 1 324 ARG 324 324 324 ARG ARG B . n 
C 1 325 ARG 325 325 325 ARG ARG B . n 
C 1 326 PHE 326 326 326 PHE PHE B . n 
C 1 327 PHE 327 327 327 PHE PHE B . n 
C 1 328 ALA 328 328 328 ALA ALA B . n 
C 1 329 PHE 329 329 329 PHE PHE B . n 
C 1 330 LEU 330 330 330 LEU LEU B . n 
C 1 331 ASN 331 331 331 ASN ASN B . n 
C 1 332 GLU 332 332 332 GLU GLU B . n 
C 1 333 ARG 333 333 333 ARG ARG B . n 
C 1 334 MET 334 334 334 MET MET B . n 
C 1 335 GLU 335 335 335 GLU GLU B . n 
C 1 336 LYS 336 336 336 LYS LYS B . n 
C 1 337 VAL 337 337 337 VAL VAL B . n 
C 1 338 ASN 338 338 338 ASN ASN B . n 
C 1 339 GLY 339 339 339 GLY GLY B . n 
C 1 340 GLU 340 340 ?   ?   ?   B . n 
C 1 341 ASN 341 341 ?   ?   ?   B . n 
C 1 342 LEU 342 342 ?   ?   ?   B . n 
C 1 343 TYR 343 343 ?   ?   ?   B . n 
C 1 344 PHE 344 344 ?   ?   ?   B . n 
C 1 345 GLN 345 345 ?   ?   ?   B . n 
C 1 346 SER 346 346 ?   ?   ?   B . n 
C 1 347 HIS 347 347 ?   ?   ?   B . n 
C 1 348 HIS 348 348 ?   ?   ?   B . n 
C 1 349 HIS 349 349 ?   ?   ?   B . n 
C 1 350 HIS 350 350 ?   ?   ?   B . n 
C 1 351 HIS 351 351 ?   ?   ?   B . n 
C 1 352 HIS 352 352 ?   ?   ?   B . n 
D 2 1   DG  1   -46 ?   ?   ?   D . n 
D 2 2   DA  2   -45 ?   ?   ?   D . n 
D 2 3   DT  3   -44 ?   ?   ?   D . n 
D 2 4   DG  4   -43 ?   ?   ?   D . n 
D 2 5   DC  5   -42 ?   ?   ?   D . n 
D 2 6   DG  6   -41 ?   ?   ?   D . n 
D 2 7   DT  7   -40 ?   ?   ?   D . n 
D 2 8   DG  8   -39 ?   ?   ?   D . n 
D 2 9   DG  9   -38 ?   ?   ?   D . n 
D 2 10  DG  10  -37 ?   ?   ?   D . n 
D 2 11  DT  11  -36 ?   ?   ?   D . n 
D 2 12  DC  12  -35 ?   ?   ?   D . n 
D 2 13  DT  13  -34 ?   ?   ?   D . n 
D 2 14  DT  14  -33 ?   ?   ?   D . n 
D 2 15  DC  15  -32 ?   ?   ?   D . n 
D 2 16  DA  16  -31 ?   ?   ?   D . n 
D 2 17  DC  17  -30 ?   ?   ?   D . n 
D 2 18  DA  18  -29 ?   ?   ?   D . n 
D 2 19  DC  19  -28 ?   ?   ?   D . n 
D 2 20  DC  20  -27 ?   ?   ?   D . n 
D 2 21  DG  21  -26 ?   ?   ?   D . n 
D 2 22  DG  22  -25 ?   ?   ?   D . n 
D 2 23  DT  23  -24 ?   ?   ?   D . n 
D 2 24  DG  24  -23 ?   ?   ?   D . n 
D 2 25  DG  25  -22 ?   ?   ?   D . n 
D 2 26  DA  26  -21 ?   ?   ?   D . n 
D 2 27  DT  27  -20 ?   ?   ?   D . n 
D 2 28  DG  28  -19 ?   ?   ?   D . n 
D 2 29  DC  29  -18 ?   ?   ?   D . n 
D 2 30  DG  30  -17 ?   ?   ?   D . n 
D 2 31  DT  31  -16 ?   ?   ?   D . n 
D 2 32  DG  32  -15 ?   ?   ?   D . n 
D 2 33  DG  33  -14 ?   ?   ?   D . n 
D 2 34  DG  34  -13 ?   ?   ?   D . n 
D 2 35  DT  35  -12 ?   ?   ?   D . n 
D 2 36  DC  36  -11 ?   ?   ?   D . n 
D 2 37  DT  37  -10 ?   ?   ?   D . n 
D 2 38  DT  38  -9  ?   ?   ?   D . n 
D 2 39  DC  39  -8  ?   ?   ?   D . n 
D 2 40  DA  40  -7  ?   ?   ?   D . n 
D 2 41  DT  41  -6  ?   ?   ?   D . n 
D 2 42  DG  42  -5  ?   ?   ?   D . n 
D 2 43  DA  43  -4  ?   ?   ?   D . n 
D 2 44  DA  44  -3  ?   ?   ?   D . n 
D 2 45  DG  45  -2  ?   ?   ?   D . n 
D 2 46  DA  46  -1  ?   ?   ?   D . n 
D 2 47  DC  47  0   ?   ?   ?   D . n 
D 2 48  DC  48  1   1   DC  DC  D . n 
D 2 49  DC  49  2   2   DC  DC  D . n 
D 2 50  DA  50  3   3   DA  DA  D . n 
D 2 51  DC  51  4   4   DC  DC  D . n 
D 2 52  DG  52  5   5   DG  DG  D . n 
D 2 53  DC  53  6   6   DC  DC  D . n 
D 2 54  DA  54  7   7   DA  DA  D . n 
D 2 55  DT  55  8   8   DT  DT  D . n 
D 2 56  DC  56  9   9   DC  DC  D . n 
D 2 57  DC  57  10  10  DC  DC  D . n 
D 2 58  DA  58  11  11  DA  DA  D . n 
D 2 59  DC  59  12  12  DC  DC  D . n 
D 2 60  DC  60  13  13  DC  DC  D . n 
D 2 61  DG  61  14  14  DG  DG  D . n 
D 2 62  DG  62  15  15  DG  DG  D . n 
D 2 63  DT  63  16  16  DT  DT  D . n 
D 2 64  DG  64  17  17  DG  DG  D . n 
D 2 65  DT  65  18  18  DT  DT  D . n 
D 2 66  DG  66  19  19  DG  DG  D . n 
D 2 67  DA  67  20  20  DA  DA  D . n 
D 2 68  DA  68  21  21  DA  DA  D . n 
D 2 69  DG  69  22  22  DG  DG  D . n 
D 2 70  DA  70  23  23  DA  DA  D . n 
D 2 71  DC  71  24  24  DC  DC  D . n 
D 2 72  DC  72  25  25  DC  DC  D . n 
D 2 73  DC  73  26  26  DC  DC  D . n 
D 2 74  DA  74  27  ?   ?   ?   D . n 
D 2 75  DC  75  28  ?   ?   ?   D . n 
D 2 76  DG  76  29  ?   ?   ?   D . n 
D 2 77  DC  77  30  ?   ?   ?   D . n 
D 2 78  DA  78  31  ?   ?   ?   D . n 
D 2 79  DT  79  32  ?   ?   ?   D . n 
D 2 80  DC  80  33  ?   ?   ?   D . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        MG 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   MG 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 MG  1 401 1 MG  MG  A . 
F 3 MG  1 401 2 MG  MG  B . 
G 4 HOH 1 501 1 HOH HOH A . 
G 4 HOH 2 502 9 HOH HOH A . 
G 4 HOH 3 503 5 HOH HOH A . 
G 4 HOH 4 504 3 HOH HOH A . 
H 4 HOH 1 501 7 HOH HOH B . 
H 4 HOH 2 502 6 HOH HOH B . 
H 4 HOH 3 503 8 HOH HOH B . 
H 4 HOH 4 504 2 HOH HOH B . 
H 4 HOH 5 505 4 HOH HOH B . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1 1 Y 1 A TRP 126 ? O   ? A TRP 126 O   
2 1 Y 1 B TRP 126 ? O   ? C TRP 126 O   
3 1 Y 1 D DC  1   ? P   ? D DC  48  P   
4 1 Y 1 D DC  1   ? OP1 ? D DC  48  OP1 
5 1 Y 1 D DC  1   ? OP2 ? D DC  48  OP2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BGJ 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BGJ 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BGJ 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BGJ 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003  ? 6590 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.515  ? 9160 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 23.424 ? 1305 ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.039  ? 1010 ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.004  ? 1028 ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BGJ 
_struct.title                        'SgrAI mutant K242A endonuclease DNA-bound dimer with Mg2+ and intact primary site DNA' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BGJ 
_struct_keywords.text            
;restriction endonuclease, DNAse, allostery, bacterial innate immunity, filament, hyper-activation, substrate specificity, HYDROLASE-DNA complex, DNA BINDING PROTEIN
;
_struct_keywords.pdbx_keywords   HYDROLASE/DNA 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 1 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 4 ? 
H N N 4 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP Q9F6L0_STRGR Q9F6L0 ? 1 
;MPFTYSIEATRNLATTERCIQDIRNAPVRNRSTQFQLAQQNMLAYTFGEVIPGFASAGINGMNYRDVIGRPVENAVTEGT
HFFRDDFRVDSNAKAKVAGDIFEIVSSAVMWNCAARWNSLMVGEGWRSQPRYSRPTLSPSPRRQVAVLNLPRSFDWVSLL
VPESQEVIEEFRAGLRKDGLGLPTSTPDLAVVVLPEEFQNDEMWREEIAGLTRPNQILLSGAYQRLQGRVQPGEISLAVA
FKRSLRSDRLYQPLYEANVMQLLLEGKLGAPKVEFEVHTLAPEGTNAFVTYEAASLYGLAEGRSAVHRAIRELYVPPTAA
DLARRFFAFLNERMELVNG
;
1 
2 PDB 9BGJ         9BGJ   ? 2 ? 1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BGJ A 1 ? 339 ? Q9F6L0 1   ? 339 ? 1   339 
2 2 9BGJ C 1 ? 80  ? 9BGJ   -6  ? 73  ? -6  73  
3 1 9BGJ B 1 ? 339 ? Q9F6L0 1   ? 339 ? 1   339 
4 2 9BGJ D 1 ? 80  ? 9BGJ   -46 ? 33  ? -46 33  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BGJ ASP A 63  ? UNP Q9F6L0 ASN 63  conflict              63  1  
1 9BGJ ALA A 242 ? UNP Q9F6L0 LYS 242 'engineered mutation' 242 2  
1 9BGJ LYS A 336 ? UNP Q9F6L0 LEU 336 conflict              336 3  
1 9BGJ GLU A 340 ? UNP Q9F6L0 ?   ?   'expression tag'      340 4  
1 9BGJ ASN A 341 ? UNP Q9F6L0 ?   ?   'expression tag'      341 5  
1 9BGJ LEU A 342 ? UNP Q9F6L0 ?   ?   'expression tag'      342 6  
1 9BGJ TYR A 343 ? UNP Q9F6L0 ?   ?   'expression tag'      343 7  
1 9BGJ PHE A 344 ? UNP Q9F6L0 ?   ?   'expression tag'      344 8  
1 9BGJ GLN A 345 ? UNP Q9F6L0 ?   ?   'expression tag'      345 9  
1 9BGJ SER A 346 ? UNP Q9F6L0 ?   ?   'expression tag'      346 10 
1 9BGJ HIS A 347 ? UNP Q9F6L0 ?   ?   'expression tag'      347 11 
1 9BGJ HIS A 348 ? UNP Q9F6L0 ?   ?   'expression tag'      348 12 
1 9BGJ HIS A 349 ? UNP Q9F6L0 ?   ?   'expression tag'      349 13 
1 9BGJ HIS A 350 ? UNP Q9F6L0 ?   ?   'expression tag'      350 14 
1 9BGJ HIS A 351 ? UNP Q9F6L0 ?   ?   'expression tag'      351 15 
1 9BGJ HIS A 352 ? UNP Q9F6L0 ?   ?   'expression tag'      352 16 
3 9BGJ ASP B 63  ? UNP Q9F6L0 ASN 63  conflict              63  17 
3 9BGJ ALA B 242 ? UNP Q9F6L0 LYS 242 'engineered mutation' 242 18 
3 9BGJ LYS B 336 ? UNP Q9F6L0 LEU 336 conflict              336 19 
3 9BGJ GLU B 340 ? UNP Q9F6L0 ?   ?   'expression tag'      340 20 
3 9BGJ ASN B 341 ? UNP Q9F6L0 ?   ?   'expression tag'      341 21 
3 9BGJ LEU B 342 ? UNP Q9F6L0 ?   ?   'expression tag'      342 22 
3 9BGJ TYR B 343 ? UNP Q9F6L0 ?   ?   'expression tag'      343 23 
3 9BGJ PHE B 344 ? UNP Q9F6L0 ?   ?   'expression tag'      344 24 
3 9BGJ GLN B 345 ? UNP Q9F6L0 ?   ?   'expression tag'      345 25 
3 9BGJ SER B 346 ? UNP Q9F6L0 ?   ?   'expression tag'      346 26 
3 9BGJ HIS B 347 ? UNP Q9F6L0 ?   ?   'expression tag'      347 27 
3 9BGJ HIS B 348 ? UNP Q9F6L0 ?   ?   'expression tag'      348 28 
3 9BGJ HIS B 349 ? UNP Q9F6L0 ?   ?   'expression tag'      349 29 
3 9BGJ HIS B 350 ? UNP Q9F6L0 ?   ?   'expression tag'      350 30 
3 9BGJ HIS B 351 ? UNP Q9F6L0 ?   ?   'expression tag'      351 31 
3 9BGJ HIS B 352 ? UNP Q9F6L0 ?   ?   'expression tag'      352 32 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 6   ? LEU A 13  ? SER A 6   LEU A 13  1 ? 8  
HELX_P HELX_P2  AA2 ALA A 14  ? ARG A 18  ? ALA A 14  ARG A 18  5 ? 5  
HELX_P HELX_P3  AA3 ALA A 38  ? PHE A 47  ? ALA A 38  PHE A 47  1 ? 10 
HELX_P HELX_P4  AA4 SER A 56  ? GLY A 61  ? SER A 56  GLY A 61  1 ? 6  
HELX_P HELX_P5  AA5 ASP A 63  ? ILE A 68  ? ASP A 63  ILE A 68  1 ? 6  
HELX_P HELX_P6  AA6 GLY A 69  ? PHE A 83  ? GLY A 69  PHE A 83  1 ? 15 
HELX_P HELX_P7  AA7 ASP A 90  ? GLY A 123 ? ASP A 90  GLY A 123 1 ? 34 
HELX_P HELX_P8  AA8 SER A 140 ? ARG A 143 ? SER A 140 ARG A 143 5 ? 4  
HELX_P HELX_P9  AA9 VAL A 161 ? LYS A 177 ? VAL A 161 LYS A 177 1 ? 17 
HELX_P HELX_P10 AB1 PRO A 195 ? GLN A 199 ? PRO A 195 GLN A 199 5 ? 5  
HELX_P HELX_P11 AB2 GLU A 202 ? GLU A 206 ? GLU A 202 GLU A 206 5 ? 5  
HELX_P HELX_P12 AB3 THR A 212 ? GLY A 221 ? THR A 212 GLY A 221 1 ? 10 
HELX_P HELX_P13 AB4 ALA A 222 ? GLN A 227 ? ALA A 222 GLN A 227 5 ? 6  
HELX_P HELX_P14 AB5 GLN A 231 ? ILE A 235 ? GLN A 231 ILE A 235 5 ? 5  
HELX_P HELX_P15 AB6 LEU A 250 ? LEU A 263 ? LEU A 250 LEU A 263 1 ? 14 
HELX_P HELX_P16 AB7 ASN A 286 ? TYR A 291 ? ASN A 286 TYR A 291 1 ? 6  
HELX_P HELX_P17 AB8 THR A 318 ? GLU A 335 ? THR A 318 GLU A 335 1 ? 18 
HELX_P HELX_P18 AB9 SER C 6   ? LEU C 13  ? SER B 6   LEU B 13  1 ? 8  
HELX_P HELX_P19 AC1 ALA C 14  ? ARG C 18  ? ALA B 14  ARG B 18  5 ? 5  
HELX_P HELX_P20 AC2 ALA C 38  ? PHE C 47  ? ALA B 38  PHE B 47  1 ? 10 
HELX_P HELX_P21 AC3 SER C 56  ? GLY C 61  ? SER B 56  GLY B 61  1 ? 6  
HELX_P HELX_P22 AC4 ASP C 63  ? ILE C 68  ? ASP B 63  ILE B 68  1 ? 6  
HELX_P HELX_P23 AC5 GLY C 69  ? PHE C 83  ? GLY B 69  PHE B 83  1 ? 15 
HELX_P HELX_P24 AC6 ASP C 90  ? GLY C 123 ? ASP B 90  GLY B 123 1 ? 34 
HELX_P HELX_P25 AC7 SER C 140 ? ARG C 143 ? SER B 140 ARG B 143 5 ? 4  
HELX_P HELX_P26 AC8 VAL C 161 ? LYS C 177 ? VAL B 161 LYS B 177 1 ? 17 
HELX_P HELX_P27 AC9 PRO C 195 ? GLN C 199 ? PRO B 195 GLN B 199 5 ? 5  
HELX_P HELX_P28 AD1 THR C 212 ? GLY C 221 ? THR B 212 GLY B 221 1 ? 10 
HELX_P HELX_P29 AD2 GLY C 221 ? LEU C 226 ? GLY B 221 LEU B 226 1 ? 6  
HELX_P HELX_P30 AD3 GLN C 231 ? GLY C 233 ? GLN B 231 GLY B 233 5 ? 3  
HELX_P HELX_P31 AD4 LEU C 250 ? GLU C 265 ? LEU B 250 GLU B 265 1 ? 16 
HELX_P HELX_P32 AD5 ASN C 286 ? TYR C 291 ? ASN B 286 TYR B 291 1 ? 6  
HELX_P HELX_P33 AD6 THR C 318 ? GLU C 335 ? THR B 318 GLU B 335 1 ? 18 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
metalc1  metalc ? ? A ASP 188 OD2 ? ? ? 1_555 E MG .  MG  ? ? A ASP 188 A MG 401 1_555 ? ? ? ? ? ? ?            2.609 ? ? 
metalc2  metalc ? ? A PHE 241 O   ? ? ? 1_555 E MG .  MG  ? ? A PHE 241 A MG 401 1_555 ? ? ? ? ? ? ?            2.182 ? ? 
metalc3  metalc ? ? E MG  .   MG  ? ? ? 1_555 B DC 19 OP1 ? ? A MG  401 C DC 12  1_555 ? ? ? ? ? ? ?            1.925 ? ? 
metalc4  metalc ? ? C ASP 188 OD2 ? ? ? 1_555 F MG .  MG  ? ? B ASP 188 B MG 401 1_555 ? ? ? ? ? ? ?            2.216 ? ? 
metalc5  metalc ? ? C PHE 241 O   ? ? ? 1_555 F MG .  MG  ? ? B PHE 241 B MG 401 1_555 ? ? ? ? ? ? ?            2.117 ? ? 
metalc6  metalc ? ? F MG  .   MG  ? ? ? 1_555 D DC 59 OP1 ? ? B MG  401 D DC 12  1_555 ? ? ? ? ? ? ?            1.922 ? ? 
hydrog1  hydrog ? ? B DG  9   N1  ? ? ? 1_555 D DC 72 N3  ? ? C DG  2   D DC 25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog2  hydrog ? ? B DG  9   N2  ? ? ? 1_555 D DC 72 O2  ? ? C DG  2   D DC 25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog3  hydrog ? ? B DG  9   O6  ? ? ? 1_555 D DC 72 N4  ? ? C DG  2   D DC 25  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog4  hydrog ? ? B DG  10  N1  ? ? ? 1_555 D DC 71 N3  ? ? C DG  3   D DC 24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog5  hydrog ? ? B DG  10  N2  ? ? ? 1_555 D DC 71 O2  ? ? C DG  3   D DC 24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog6  hydrog ? ? B DG  10  O6  ? ? ? 1_555 D DC 71 N4  ? ? C DG  3   D DC 24  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog7  hydrog ? ? B DT  11  N3  ? ? ? 1_555 D DA 70 N1  ? ? C DT  4   D DA 23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog8  hydrog ? ? B DT  11  O4  ? ? ? 1_555 D DA 70 N6  ? ? C DT  4   D DA 23  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog9  hydrog ? ? B DC  12  N3  ? ? ? 1_555 D DG 69 N1  ? ? C DC  5   D DG 22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog10 hydrog ? ? B DC  12  N4  ? ? ? 1_555 D DG 69 O6  ? ? C DC  5   D DG 22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog11 hydrog ? ? B DC  12  O2  ? ? ? 1_555 D DG 69 N2  ? ? C DC  5   D DG 22  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog12 hydrog ? ? B DT  13  N3  ? ? ? 1_555 D DA 68 N1  ? ? C DT  6   D DA 21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog13 hydrog ? ? B DT  13  O4  ? ? ? 1_555 D DA 68 N6  ? ? C DT  6   D DA 21  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog14 hydrog ? ? B DT  14  N3  ? ? ? 1_555 D DA 67 N1  ? ? C DT  7   D DA 20  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog15 hydrog ? ? B DT  14  O4  ? ? ? 1_555 D DA 67 N6  ? ? C DT  7   D DA 20  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog16 hydrog ? ? B DC  15  N3  ? ? ? 1_555 D DG 66 N1  ? ? C DC  8   D DG 19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog17 hydrog ? ? B DC  15  N4  ? ? ? 1_555 D DG 66 O6  ? ? C DC  8   D DG 19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog18 hydrog ? ? B DC  15  O2  ? ? ? 1_555 D DG 66 N2  ? ? C DC  8   D DG 19  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog19 hydrog ? ? B DA  16  N1  ? ? ? 1_555 D DT 65 N3  ? ? C DA  9   D DT 18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog20 hydrog ? ? B DA  16  N6  ? ? ? 1_555 D DT 65 O4  ? ? C DA  9   D DT 18  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog21 hydrog ? ? B DC  17  N3  ? ? ? 1_555 D DG 64 N1  ? ? C DC  10  D DG 17  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog22 hydrog ? ? B DC  17  N4  ? ? ? 1_555 D DG 64 O6  ? ? C DC  10  D DG 17  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog23 hydrog ? ? B DC  17  O2  ? ? ? 1_555 D DG 64 N2  ? ? C DC  10  D DG 17  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog24 hydrog ? ? B DA  18  N1  ? ? ? 1_555 D DT 63 N3  ? ? C DA  11  D DT 16  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog25 hydrog ? ? B DA  18  N6  ? ? ? 1_555 D DT 63 O4  ? ? C DA  11  D DT 16  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog26 hydrog ? ? B DC  19  N3  ? ? ? 1_555 D DG 62 N1  ? ? C DC  12  D DG 15  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog27 hydrog ? ? B DC  19  N4  ? ? ? 1_555 D DG 62 O6  ? ? C DC  12  D DG 15  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog28 hydrog ? ? B DC  19  O2  ? ? ? 1_555 D DG 62 N2  ? ? C DC  12  D DG 15  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog29 hydrog ? ? B DC  20  N3  ? ? ? 1_555 D DG 61 N1  ? ? C DC  13  D DG 14  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog30 hydrog ? ? B DC  20  N4  ? ? ? 1_555 D DG 61 O6  ? ? C DC  13  D DG 14  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog31 hydrog ? ? B DC  20  O2  ? ? ? 1_555 D DG 61 N2  ? ? C DC  13  D DG 14  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog32 hydrog ? ? B DG  21  N1  ? ? ? 1_555 D DC 60 N3  ? ? C DG  14  D DC 13  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog33 hydrog ? ? B DG  21  N2  ? ? ? 1_555 D DC 60 O2  ? ? C DG  14  D DC 13  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog34 hydrog ? ? B DG  21  O6  ? ? ? 1_555 D DC 60 N4  ? ? C DG  14  D DC 13  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog35 hydrog ? ? B DG  22  N1  ? ? ? 1_555 D DC 59 N3  ? ? C DG  15  D DC 12  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog36 hydrog ? ? B DG  22  N2  ? ? ? 1_555 D DC 59 O2  ? ? C DG  15  D DC 12  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog37 hydrog ? ? B DG  22  O6  ? ? ? 1_555 D DC 59 N4  ? ? C DG  15  D DC 12  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog38 hydrog ? ? B DT  23  N3  ? ? ? 1_555 D DA 58 N1  ? ? C DT  16  D DA 11  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog39 hydrog ? ? B DT  23  O4  ? ? ? 1_555 D DA 58 N6  ? ? C DT  16  D DA 11  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog40 hydrog ? ? B DG  24  N1  ? ? ? 1_555 D DC 57 N3  ? ? C DG  17  D DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog41 hydrog ? ? B DG  24  N2  ? ? ? 1_555 D DC 57 O2  ? ? C DG  17  D DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog42 hydrog ? ? B DG  24  O6  ? ? ? 1_555 D DC 57 N4  ? ? C DG  17  D DC 10  1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog43 hydrog ? ? B DG  25  N1  ? ? ? 1_555 D DC 56 N3  ? ? C DG  18  D DC 9   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog44 hydrog ? ? B DG  25  N2  ? ? ? 1_555 D DC 56 O2  ? ? C DG  18  D DC 9   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog45 hydrog ? ? B DG  25  O6  ? ? ? 1_555 D DC 56 N4  ? ? C DG  18  D DC 9   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog46 hydrog ? ? B DA  26  N1  ? ? ? 1_555 D DT 55 N3  ? ? C DA  19  D DT 8   1_555 ? ? ? ? ? ? 'DA-DT PAIR' ?     ? ? 
hydrog47 hydrog ? ? B DT  27  N3  ? ? ? 1_555 D DA 54 N1  ? ? C DT  20  D DA 7   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog48 hydrog ? ? B DT  27  O4  ? ? ? 1_555 D DA 54 N6  ? ? C DT  20  D DA 7   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog49 hydrog ? ? B DC  29  N3  ? ? ? 1_555 D DG 52 N1  ? ? C DC  22  D DG 5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog50 hydrog ? ? B DC  29  N4  ? ? ? 1_555 D DG 52 O6  ? ? C DC  22  D DG 5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog51 hydrog ? ? B DC  29  O2  ? ? ? 1_555 D DG 52 N2  ? ? C DC  22  D DG 5   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog52 hydrog ? ? B DG  30  N2  ? ? ? 1_555 D DC 51 O2  ? ? C DG  23  D DC 4   1_555 ? ? ? ? ? ? 'DG-DC PAIR' ?     ? ? 
hydrog53 hydrog ? ? B DT  31  N3  ? ? ? 1_555 D DA 50 N1  ? ? C DT  24  D DA 3   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog54 hydrog ? ? B DT  31  O4  ? ? ? 1_555 D DA 50 N6  ? ? C DT  24  D DA 3   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog55 hydrog ? ? B DG  32  N1  ? ? ? 1_555 D DC 49 N3  ? ? C DG  25  D DC 2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog56 hydrog ? ? B DG  32  N2  ? ? ? 1_555 D DC 49 O2  ? ? C DG  25  D DC 2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
hydrog57 hydrog ? ? B DG  32  O6  ? ? ? 1_555 D DC 49 N4  ? ? C DG  25  D DC 2   1_555 ? ? ? ? ? ? WATSON-CRICK ?     ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
metalc ? ? 
hydrog ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1 OD2 ? A ASP 188 ? A ASP 188 ? 1_555 MG ? E MG . ? A MG 401 ? 1_555 O   ? A PHE 241 ? A PHE 241 ? 1_555 88.4  ? 
2 OD2 ? A ASP 188 ? A ASP 188 ? 1_555 MG ? E MG . ? A MG 401 ? 1_555 OP1 ? B DC  19  ? C DC  12  ? 1_555 75.0  ? 
3 O   ? A PHE 241 ? A PHE 241 ? 1_555 MG ? E MG . ? A MG 401 ? 1_555 OP1 ? B DC  19  ? C DC  12  ? 1_555 137.9 ? 
4 OD2 ? C ASP 188 ? B ASP 188 ? 1_555 MG ? F MG . ? B MG 401 ? 1_555 O   ? C PHE 241 ? B PHE 241 ? 1_555 89.1  ? 
5 OD2 ? C ASP 188 ? B ASP 188 ? 1_555 MG ? F MG . ? B MG 401 ? 1_555 OP1 ? D DC  59  ? D DC  12  ? 1_555 85.0  ? 
6 O   ? C PHE 241 ? B PHE 241 ? 1_555 MG ? F MG . ? B MG 401 ? 1_555 OP1 ? D DC  59  ? D DC  12  ? 1_555 137.6 ? 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 2 ? 
AA2 ? 5 ? 
AA3 ? 2 ? 
AA4 ? 5 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? parallel      
AA2 4 5 ? parallel      
AA3 1 2 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 ILE A 20  ? ASP A 22  ? ILE A 20  ASP A 22  
AA1 2 PHE A 35  ? LEU A 37  ? PHE A 35  LEU A 37  
AA2 1 VAL A 145 ? LEU A 148 ? VAL A 145 LEU A 148 
AA2 2 LEU A 189 ? VAL A 193 ? LEU A 189 VAL A 193 
AA2 3 LEU A 237 ? PHE A 241 ? LEU A 237 PHE A 241 
AA2 4 PHE A 275 ? HIS A 278 ? PHE A 275 HIS A 278 
AA2 5 LEU A 313 ? TYR A 314 ? LEU A 313 TYR A 314 
AA3 1 ILE C 20  ? ASP C 22  ? ILE B 20  ASP B 22  
AA3 2 PHE C 35  ? LEU C 37  ? PHE B 35  LEU B 37  
AA4 1 VAL C 145 ? LEU C 148 ? VAL B 145 LEU B 148 
AA4 2 LEU C 189 ? VAL C 193 ? LEU B 189 VAL B 193 
AA4 3 ILE C 235 ? PHE C 241 ? ILE B 235 PHE B 241 
AA4 4 PHE C 275 ? HIS C 278 ? PHE B 275 HIS B 278 
AA4 5 LEU C 313 ? TYR C 314 ? LEU B 313 TYR B 314 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 21  ? N GLN A 21  O GLN A 36  ? O GLN A 36  
AA2 1 2 N ALA A 146 ? N ALA A 146 O VAL A 192 ? O VAL A 192 
AA2 2 3 N LEU A 189 ? N LEU A 189 O VAL A 239 ? O VAL A 239 
AA2 3 4 N ALA A 240 ? N ALA A 240 O HIS A 278 ? O HIS A 278 
AA2 4 5 N VAL A 277 ? N VAL A 277 O TYR A 314 ? O TYR A 314 
AA3 1 2 N GLN C 21  ? N GLN B 21  O GLN C 36  ? O GLN B 36  
AA4 1 2 N LEU C 148 ? N LEU B 148 O ALA C 190 ? O ALA B 190 
AA4 2 3 N LEU C 189 ? N LEU B 189 O VAL C 239 ? O VAL B 239 
AA4 3 4 N ALA C 240 ? N ALA B 240 O HIS C 278 ? O HIS B 278 
AA4 4 5 N VAL C 277 ? N VAL B 277 O TYR C 314 ? O TYR B 314 
# 
_pdbx_entry_details.entry_id                   9BGJ 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ALA A 55  ? ? -125.58 -166.32 
2  1 THR A 136 ? ? -92.75  53.69   
3  1 TRP A 156 ? ? 72.65   -7.04   
4  1 LEU A 211 ? ? -94.44  56.82   
5  1 PRO A 282 ? ? -82.95  45.86   
6  1 LEU A 296 ? ? -55.97  -8.72   
7  1 TYR A 297 ? ? 66.36   -4.29   
8  1 ALA B 55  ? ? -125.69 -166.87 
9  1 THR B 136 ? ? -93.19  54.33   
10 1 TRP B 156 ? ? 72.07   -8.55   
11 1 LEU B 211 ? ? -93.97  56.98   
12 1 PRO B 282 ? ? -82.42  46.36   
13 1 ALA B 305 ? ? -98.80  32.17   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BGJ 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   'Correlation coefficient' 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         REAL 
_em_3d_fitting.ref_protocol      'FLEXIBLE FIT' 
# 
_em_3d_fitting_list.id                            1 
_em_3d_fitting_list.3d_fitting_id                 1 
_em_3d_fitting_list.pdb_entry_id                  6OBJ 
_em_3d_fitting_list.pdb_chain_id                  ? 
_em_3d_fitting_list.pdb_chain_residue_range       ? 
_em_3d_fitting_list.details                       ? 
_em_3d_fitting_list.chain_id                      ? 
_em_3d_fitting_list.chain_residue_range           ? 
_em_3d_fitting_list.source_name                   PDB 
_em_3d_fitting_list.type                          'experimental model' 
_em_3d_fitting_list.accession_code                6OBJ 
_em_3d_fitting_list.initial_refinement_model_id   1 
# 
_em_3d_reconstruction.entry_id                    9BGJ 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.34 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               357489 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               HELICAL 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.0 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Filamentous SgrAI mutant K242A endonuclease with Mg2+ and intact primary site DNA' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1,2 
# 
_em_image_scans.entry_id                9BGJ 
_em_image_scans.id                      1 
_em_image_scans.number_digital_images   ? 
_em_image_scans.details                 ? 
_em_image_scans.scanner_model           ? 
_em_image_scans.sampling_size           ? 
_em_image_scans.od_range                ? 
_em_image_scans.quant_bit_size          ? 
_em_image_scans.citation_id             ? 
_em_image_scans.dimension_height        4092 
_em_image_scans.dimension_width         5760 
_em_image_scans.frames_per_image        50 
_em_image_scans.image_recording_id      1 
_em_image_scans.used_frames_per_image   1-50 
# 
_em_imaging.entry_id                        9BGJ 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           'FEI TITAN KRIOS AUTOGRID HOLDER' 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      2.7 
_em_imaging.nominal_defocus_min             1000 
_em_imaging.nominal_defocus_max             2500 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           105000 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             'COMA FREE' 
_em_imaging.c2_aperture_diameter            70 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         NITROGEN 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   300 
_em_sample_support.grid_type        'UltrAuFoil R1.2/1.3' 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BGJ 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'HOMEMADE PLUNGER' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               'Cryo-EM grids were prepared by freezing using a manual plunger in cold room at 4C' 
# 
_em_experiment.entry_id                9BGJ 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   HELICAL 
_em_experiment.aggregation_state       FILAMENT 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A GLU 340 ? A GLU 340 
3   1 Y 1 A ASN 341 ? A ASN 341 
4   1 Y 1 A LEU 342 ? A LEU 342 
5   1 Y 1 A TYR 343 ? A TYR 343 
6   1 Y 1 A PHE 344 ? A PHE 344 
7   1 Y 1 A GLN 345 ? A GLN 345 
8   1 Y 1 A SER 346 ? A SER 346 
9   1 Y 1 A HIS 347 ? A HIS 347 
10  1 Y 1 A HIS 348 ? A HIS 348 
11  1 Y 1 A HIS 349 ? A HIS 349 
12  1 Y 1 A HIS 350 ? A HIS 350 
13  1 Y 1 A HIS 351 ? A HIS 351 
14  1 Y 1 A HIS 352 ? A HIS 352 
15  1 Y 1 C DG  -6  ? B DG  1   
16  1 Y 1 C DA  -5  ? B DA  2   
17  1 Y 1 C DT  -4  ? B DT  3   
18  1 Y 1 C DG  -3  ? B DG  4   
19  1 Y 1 C DC  -2  ? B DC  5   
20  1 Y 1 C DG  -1  ? B DG  6   
21  1 Y 1 C DT  0   ? B DT  7   
22  1 Y 1 C DG  1   ? B DG  8   
23  1 Y 1 C DG  27  ? B DG  34  
24  1 Y 1 C DT  28  ? B DT  35  
25  1 Y 1 C DC  29  ? B DC  36  
26  1 Y 1 C DT  30  ? B DT  37  
27  1 Y 1 C DT  31  ? B DT  38  
28  1 Y 1 C DC  32  ? B DC  39  
29  1 Y 1 C DA  33  ? B DA  40  
30  1 Y 1 C DT  34  ? B DT  41  
31  1 Y 1 C DG  35  ? B DG  42  
32  1 Y 1 C DA  36  ? B DA  43  
33  1 Y 1 C DA  37  ? B DA  44  
34  1 Y 1 C DG  38  ? B DG  45  
35  1 Y 1 C DA  39  ? B DA  46  
36  1 Y 1 C DC  40  ? B DC  47  
37  1 Y 1 C DC  41  ? B DC  48  
38  1 Y 1 C DC  42  ? B DC  49  
39  1 Y 1 C DA  43  ? B DA  50  
40  1 Y 1 C DC  44  ? B DC  51  
41  1 Y 1 C DG  45  ? B DG  52  
42  1 Y 1 C DC  46  ? B DC  53  
43  1 Y 1 C DA  47  ? B DA  54  
44  1 Y 1 C DT  48  ? B DT  55  
45  1 Y 1 C DC  49  ? B DC  56  
46  1 Y 1 C DC  50  ? B DC  57  
47  1 Y 1 C DA  51  ? B DA  58  
48  1 Y 1 C DC  52  ? B DC  59  
49  1 Y 1 C DC  53  ? B DC  60  
50  1 Y 1 C DG  54  ? B DG  61  
51  1 Y 1 C DG  55  ? B DG  62  
52  1 Y 1 C DT  56  ? B DT  63  
53  1 Y 1 C DG  57  ? B DG  64  
54  1 Y 1 C DT  58  ? B DT  65  
55  1 Y 1 C DG  59  ? B DG  66  
56  1 Y 1 C DA  60  ? B DA  67  
57  1 Y 1 C DA  61  ? B DA  68  
58  1 Y 1 C DG  62  ? B DG  69  
59  1 Y 1 C DA  63  ? B DA  70  
60  1 Y 1 C DC  64  ? B DC  71  
61  1 Y 1 C DC  65  ? B DC  72  
62  1 Y 1 C DC  66  ? B DC  73  
63  1 Y 1 C DA  67  ? B DA  74  
64  1 Y 1 C DC  68  ? B DC  75  
65  1 Y 1 C DG  69  ? B DG  76  
66  1 Y 1 C DC  70  ? B DC  77  
67  1 Y 1 C DA  71  ? B DA  78  
68  1 Y 1 C DT  72  ? B DT  79  
69  1 Y 1 C DC  73  ? B DC  80  
70  1 Y 1 B MET 1   ? C MET 1   
71  1 Y 1 B ALA 300 ? C ALA 300 
72  1 Y 1 B GLU 301 ? C GLU 301 
73  1 Y 1 B GLY 302 ? C GLY 302 
74  1 Y 1 B ARG 303 ? C ARG 303 
75  1 Y 1 B GLU 340 ? C GLU 340 
76  1 Y 1 B ASN 341 ? C ASN 341 
77  1 Y 1 B LEU 342 ? C LEU 342 
78  1 Y 1 B TYR 343 ? C TYR 343 
79  1 Y 1 B PHE 344 ? C PHE 344 
80  1 Y 1 B GLN 345 ? C GLN 345 
81  1 Y 1 B SER 346 ? C SER 346 
82  1 Y 1 B HIS 347 ? C HIS 347 
83  1 Y 1 B HIS 348 ? C HIS 348 
84  1 Y 1 B HIS 349 ? C HIS 349 
85  1 Y 1 B HIS 350 ? C HIS 350 
86  1 Y 1 B HIS 351 ? C HIS 351 
87  1 Y 1 B HIS 352 ? C HIS 352 
88  1 Y 1 D DG  -46 ? D DG  1   
89  1 Y 1 D DA  -45 ? D DA  2   
90  1 Y 1 D DT  -44 ? D DT  3   
91  1 Y 1 D DG  -43 ? D DG  4   
92  1 Y 1 D DC  -42 ? D DC  5   
93  1 Y 1 D DG  -41 ? D DG  6   
94  1 Y 1 D DT  -40 ? D DT  7   
95  1 Y 1 D DG  -39 ? D DG  8   
96  1 Y 1 D DG  -38 ? D DG  9   
97  1 Y 1 D DG  -37 ? D DG  10  
98  1 Y 1 D DT  -36 ? D DT  11  
99  1 Y 1 D DC  -35 ? D DC  12  
100 1 Y 1 D DT  -34 ? D DT  13  
101 1 Y 1 D DT  -33 ? D DT  14  
102 1 Y 1 D DC  -32 ? D DC  15  
103 1 Y 1 D DA  -31 ? D DA  16  
104 1 Y 1 D DC  -30 ? D DC  17  
105 1 Y 1 D DA  -29 ? D DA  18  
106 1 Y 1 D DC  -28 ? D DC  19  
107 1 Y 1 D DC  -27 ? D DC  20  
108 1 Y 1 D DG  -26 ? D DG  21  
109 1 Y 1 D DG  -25 ? D DG  22  
110 1 Y 1 D DT  -24 ? D DT  23  
111 1 Y 1 D DG  -23 ? D DG  24  
112 1 Y 1 D DG  -22 ? D DG  25  
113 1 Y 1 D DA  -21 ? D DA  26  
114 1 Y 1 D DT  -20 ? D DT  27  
115 1 Y 1 D DG  -19 ? D DG  28  
116 1 Y 1 D DC  -18 ? D DC  29  
117 1 Y 1 D DG  -17 ? D DG  30  
118 1 Y 1 D DT  -16 ? D DT  31  
119 1 Y 1 D DG  -15 ? D DG  32  
120 1 Y 1 D DG  -14 ? D DG  33  
121 1 Y 1 D DG  -13 ? D DG  34  
122 1 Y 1 D DT  -12 ? D DT  35  
123 1 Y 1 D DC  -11 ? D DC  36  
124 1 Y 1 D DT  -10 ? D DT  37  
125 1 Y 1 D DT  -9  ? D DT  38  
126 1 Y 1 D DC  -8  ? D DC  39  
127 1 Y 1 D DA  -7  ? D DA  40  
128 1 Y 1 D DT  -6  ? D DT  41  
129 1 Y 1 D DG  -5  ? D DG  42  
130 1 Y 1 D DA  -4  ? D DA  43  
131 1 Y 1 D DA  -3  ? D DA  44  
132 1 Y 1 D DG  -2  ? D DG  45  
133 1 Y 1 D DA  -1  ? D DA  46  
134 1 Y 1 D DC  0   ? D DC  47  
135 1 Y 1 D DA  27  ? D DA  74  
136 1 Y 1 D DC  28  ? D DC  75  
137 1 Y 1 D DG  29  ? D DG  76  
138 1 Y 1 D DC  30  ? D DC  77  
139 1 Y 1 D DA  31  ? D DA  78  
140 1 Y 1 D DT  32  ? D DT  79  
141 1 Y 1 D DC  33  ? D DC  80  
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N      N  N N 1   
ALA CA     C  N S 2   
ALA C      C  N N 3   
ALA O      O  N N 4   
ALA CB     C  N N 5   
ALA OXT    O  N N 6   
ALA H      H  N N 7   
ALA H2     H  N N 8   
ALA HA     H  N N 9   
ALA HB1    H  N N 10  
ALA HB2    H  N N 11  
ALA HB3    H  N N 12  
ALA HXT    H  N N 13  
ARG N      N  N N 14  
ARG CA     C  N S 15  
ARG C      C  N N 16  
ARG O      O  N N 17  
ARG CB     C  N N 18  
ARG CG     C  N N 19  
ARG CD     C  N N 20  
ARG NE     N  N N 21  
ARG CZ     C  N N 22  
ARG NH1    N  N N 23  
ARG NH2    N  N N 24  
ARG OXT    O  N N 25  
ARG H      H  N N 26  
ARG H2     H  N N 27  
ARG HA     H  N N 28  
ARG HB2    H  N N 29  
ARG HB3    H  N N 30  
ARG HG2    H  N N 31  
ARG HG3    H  N N 32  
ARG HD2    H  N N 33  
ARG HD3    H  N N 34  
ARG HE     H  N N 35  
ARG HH11   H  N N 36  
ARG HH12   H  N N 37  
ARG HH21   H  N N 38  
ARG HH22   H  N N 39  
ARG HXT    H  N N 40  
ASN N      N  N N 41  
ASN CA     C  N S 42  
ASN C      C  N N 43  
ASN O      O  N N 44  
ASN CB     C  N N 45  
ASN CG     C  N N 46  
ASN OD1    O  N N 47  
ASN ND2    N  N N 48  
ASN OXT    O  N N 49  
ASN H      H  N N 50  
ASN H2     H  N N 51  
ASN HA     H  N N 52  
ASN HB2    H  N N 53  
ASN HB3    H  N N 54  
ASN HD21   H  N N 55  
ASN HD22   H  N N 56  
ASN HXT    H  N N 57  
ASP N      N  N N 58  
ASP CA     C  N S 59  
ASP C      C  N N 60  
ASP O      O  N N 61  
ASP CB     C  N N 62  
ASP CG     C  N N 63  
ASP OD1    O  N N 64  
ASP OD2    O  N N 65  
ASP OXT    O  N N 66  
ASP H      H  N N 67  
ASP H2     H  N N 68  
ASP HA     H  N N 69  
ASP HB2    H  N N 70  
ASP HB3    H  N N 71  
ASP HD2    H  N N 72  
ASP HXT    H  N N 73  
CYS N      N  N N 74  
CYS CA     C  N R 75  
CYS C      C  N N 76  
CYS O      O  N N 77  
CYS CB     C  N N 78  
CYS SG     S  N N 79  
CYS OXT    O  N N 80  
CYS H      H  N N 81  
CYS H2     H  N N 82  
CYS HA     H  N N 83  
CYS HB2    H  N N 84  
CYS HB3    H  N N 85  
CYS HG     H  N N 86  
CYS HXT    H  N N 87  
DA  OP3    O  N N 88  
DA  P      P  N N 89  
DA  OP1    O  N N 90  
DA  OP2    O  N N 91  
DA  "O5'"  O  N N 92  
DA  "C5'"  C  N N 93  
DA  "C4'"  C  N R 94  
DA  "O4'"  O  N N 95  
DA  "C3'"  C  N S 96  
DA  "O3'"  O  N N 97  
DA  "C2'"  C  N N 98  
DA  "C1'"  C  N R 99  
DA  N9     N  Y N 100 
DA  C8     C  Y N 101 
DA  N7     N  Y N 102 
DA  C5     C  Y N 103 
DA  C6     C  Y N 104 
DA  N6     N  N N 105 
DA  N1     N  Y N 106 
DA  C2     C  Y N 107 
DA  N3     N  Y N 108 
DA  C4     C  Y N 109 
DA  HOP3   H  N N 110 
DA  HOP2   H  N N 111 
DA  "H5'"  H  N N 112 
DA  "H5''" H  N N 113 
DA  "H4'"  H  N N 114 
DA  "H3'"  H  N N 115 
DA  "HO3'" H  N N 116 
DA  "H2'"  H  N N 117 
DA  "H2''" H  N N 118 
DA  "H1'"  H  N N 119 
DA  H8     H  N N 120 
DA  H61    H  N N 121 
DA  H62    H  N N 122 
DA  H2     H  N N 123 
DC  OP3    O  N N 124 
DC  P      P  N N 125 
DC  OP1    O  N N 126 
DC  OP2    O  N N 127 
DC  "O5'"  O  N N 128 
DC  "C5'"  C  N N 129 
DC  "C4'"  C  N R 130 
DC  "O4'"  O  N N 131 
DC  "C3'"  C  N S 132 
DC  "O3'"  O  N N 133 
DC  "C2'"  C  N N 134 
DC  "C1'"  C  N R 135 
DC  N1     N  N N 136 
DC  C2     C  N N 137 
DC  O2     O  N N 138 
DC  N3     N  N N 139 
DC  C4     C  N N 140 
DC  N4     N  N N 141 
DC  C5     C  N N 142 
DC  C6     C  N N 143 
DC  HOP3   H  N N 144 
DC  HOP2   H  N N 145 
DC  "H5'"  H  N N 146 
DC  "H5''" H  N N 147 
DC  "H4'"  H  N N 148 
DC  "H3'"  H  N N 149 
DC  "HO3'" H  N N 150 
DC  "H2'"  H  N N 151 
DC  "H2''" H  N N 152 
DC  "H1'"  H  N N 153 
DC  H41    H  N N 154 
DC  H42    H  N N 155 
DC  H5     H  N N 156 
DC  H6     H  N N 157 
DG  OP3    O  N N 158 
DG  P      P  N N 159 
DG  OP1    O  N N 160 
DG  OP2    O  N N 161 
DG  "O5'"  O  N N 162 
DG  "C5'"  C  N N 163 
DG  "C4'"  C  N R 164 
DG  "O4'"  O  N N 165 
DG  "C3'"  C  N S 166 
DG  "O3'"  O  N N 167 
DG  "C2'"  C  N N 168 
DG  "C1'"  C  N R 169 
DG  N9     N  Y N 170 
DG  C8     C  Y N 171 
DG  N7     N  Y N 172 
DG  C5     C  Y N 173 
DG  C6     C  N N 174 
DG  O6     O  N N 175 
DG  N1     N  N N 176 
DG  C2     C  N N 177 
DG  N2     N  N N 178 
DG  N3     N  N N 179 
DG  C4     C  Y N 180 
DG  HOP3   H  N N 181 
DG  HOP2   H  N N 182 
DG  "H5'"  H  N N 183 
DG  "H5''" H  N N 184 
DG  "H4'"  H  N N 185 
DG  "H3'"  H  N N 186 
DG  "HO3'" H  N N 187 
DG  "H2'"  H  N N 188 
DG  "H2''" H  N N 189 
DG  "H1'"  H  N N 190 
DG  H8     H  N N 191 
DG  H1     H  N N 192 
DG  H21    H  N N 193 
DG  H22    H  N N 194 
DT  OP3    O  N N 195 
DT  P      P  N N 196 
DT  OP1    O  N N 197 
DT  OP2    O  N N 198 
DT  "O5'"  O  N N 199 
DT  "C5'"  C  N N 200 
DT  "C4'"  C  N R 201 
DT  "O4'"  O  N N 202 
DT  "C3'"  C  N S 203 
DT  "O3'"  O  N N 204 
DT  "C2'"  C  N N 205 
DT  "C1'"  C  N R 206 
DT  N1     N  N N 207 
DT  C2     C  N N 208 
DT  O2     O  N N 209 
DT  N3     N  N N 210 
DT  C4     C  N N 211 
DT  O4     O  N N 212 
DT  C5     C  N N 213 
DT  C7     C  N N 214 
DT  C6     C  N N 215 
DT  HOP3   H  N N 216 
DT  HOP2   H  N N 217 
DT  "H5'"  H  N N 218 
DT  "H5''" H  N N 219 
DT  "H4'"  H  N N 220 
DT  "H3'"  H  N N 221 
DT  "HO3'" H  N N 222 
DT  "H2'"  H  N N 223 
DT  "H2''" H  N N 224 
DT  "H1'"  H  N N 225 
DT  H3     H  N N 226 
DT  H71    H  N N 227 
DT  H72    H  N N 228 
DT  H73    H  N N 229 
DT  H6     H  N N 230 
GLN N      N  N N 231 
GLN CA     C  N S 232 
GLN C      C  N N 233 
GLN O      O  N N 234 
GLN CB     C  N N 235 
GLN CG     C  N N 236 
GLN CD     C  N N 237 
GLN OE1    O  N N 238 
GLN NE2    N  N N 239 
GLN OXT    O  N N 240 
GLN H      H  N N 241 
GLN H2     H  N N 242 
GLN HA     H  N N 243 
GLN HB2    H  N N 244 
GLN HB3    H  N N 245 
GLN HG2    H  N N 246 
GLN HG3    H  N N 247 
GLN HE21   H  N N 248 
GLN HE22   H  N N 249 
GLN HXT    H  N N 250 
GLU N      N  N N 251 
GLU CA     C  N S 252 
GLU C      C  N N 253 
GLU O      O  N N 254 
GLU CB     C  N N 255 
GLU CG     C  N N 256 
GLU CD     C  N N 257 
GLU OE1    O  N N 258 
GLU OE2    O  N N 259 
GLU OXT    O  N N 260 
GLU H      H  N N 261 
GLU H2     H  N N 262 
GLU HA     H  N N 263 
GLU HB2    H  N N 264 
GLU HB3    H  N N 265 
GLU HG2    H  N N 266 
GLU HG3    H  N N 267 
GLU HE2    H  N N 268 
GLU HXT    H  N N 269 
GLY N      N  N N 270 
GLY CA     C  N N 271 
GLY C      C  N N 272 
GLY O      O  N N 273 
GLY OXT    O  N N 274 
GLY H      H  N N 275 
GLY H2     H  N N 276 
GLY HA2    H  N N 277 
GLY HA3    H  N N 278 
GLY HXT    H  N N 279 
HIS N      N  N N 280 
HIS CA     C  N S 281 
HIS C      C  N N 282 
HIS O      O  N N 283 
HIS CB     C  N N 284 
HIS CG     C  Y N 285 
HIS ND1    N  Y N 286 
HIS CD2    C  Y N 287 
HIS CE1    C  Y N 288 
HIS NE2    N  Y N 289 
HIS OXT    O  N N 290 
HIS H      H  N N 291 
HIS H2     H  N N 292 
HIS HA     H  N N 293 
HIS HB2    H  N N 294 
HIS HB3    H  N N 295 
HIS HD1    H  N N 296 
HIS HD2    H  N N 297 
HIS HE1    H  N N 298 
HIS HE2    H  N N 299 
HIS HXT    H  N N 300 
HOH O      O  N N 301 
HOH H1     H  N N 302 
HOH H2     H  N N 303 
ILE N      N  N N 304 
ILE CA     C  N S 305 
ILE C      C  N N 306 
ILE O      O  N N 307 
ILE CB     C  N S 308 
ILE CG1    C  N N 309 
ILE CG2    C  N N 310 
ILE CD1    C  N N 311 
ILE OXT    O  N N 312 
ILE H      H  N N 313 
ILE H2     H  N N 314 
ILE HA     H  N N 315 
ILE HB     H  N N 316 
ILE HG12   H  N N 317 
ILE HG13   H  N N 318 
ILE HG21   H  N N 319 
ILE HG22   H  N N 320 
ILE HG23   H  N N 321 
ILE HD11   H  N N 322 
ILE HD12   H  N N 323 
ILE HD13   H  N N 324 
ILE HXT    H  N N 325 
LEU N      N  N N 326 
LEU CA     C  N S 327 
LEU C      C  N N 328 
LEU O      O  N N 329 
LEU CB     C  N N 330 
LEU CG     C  N N 331 
LEU CD1    C  N N 332 
LEU CD2    C  N N 333 
LEU OXT    O  N N 334 
LEU H      H  N N 335 
LEU H2     H  N N 336 
LEU HA     H  N N 337 
LEU HB2    H  N N 338 
LEU HB3    H  N N 339 
LEU HG     H  N N 340 
LEU HD11   H  N N 341 
LEU HD12   H  N N 342 
LEU HD13   H  N N 343 
LEU HD21   H  N N 344 
LEU HD22   H  N N 345 
LEU HD23   H  N N 346 
LEU HXT    H  N N 347 
LYS N      N  N N 348 
LYS CA     C  N S 349 
LYS C      C  N N 350 
LYS O      O  N N 351 
LYS CB     C  N N 352 
LYS CG     C  N N 353 
LYS CD     C  N N 354 
LYS CE     C  N N 355 
LYS NZ     N  N N 356 
LYS OXT    O  N N 357 
LYS H      H  N N 358 
LYS H2     H  N N 359 
LYS HA     H  N N 360 
LYS HB2    H  N N 361 
LYS HB3    H  N N 362 
LYS HG2    H  N N 363 
LYS HG3    H  N N 364 
LYS HD2    H  N N 365 
LYS HD3    H  N N 366 
LYS HE2    H  N N 367 
LYS HE3    H  N N 368 
LYS HZ1    H  N N 369 
LYS HZ2    H  N N 370 
LYS HZ3    H  N N 371 
LYS HXT    H  N N 372 
MET N      N  N N 373 
MET CA     C  N S 374 
MET C      C  N N 375 
MET O      O  N N 376 
MET CB     C  N N 377 
MET CG     C  N N 378 
MET SD     S  N N 379 
MET CE     C  N N 380 
MET OXT    O  N N 381 
MET H      H  N N 382 
MET H2     H  N N 383 
MET HA     H  N N 384 
MET HB2    H  N N 385 
MET HB3    H  N N 386 
MET HG2    H  N N 387 
MET HG3    H  N N 388 
MET HE1    H  N N 389 
MET HE2    H  N N 390 
MET HE3    H  N N 391 
MET HXT    H  N N 392 
MG  MG     MG N N 393 
PHE N      N  N N 394 
PHE CA     C  N S 395 
PHE C      C  N N 396 
PHE O      O  N N 397 
PHE CB     C  N N 398 
PHE CG     C  Y N 399 
PHE CD1    C  Y N 400 
PHE CD2    C  Y N 401 
PHE CE1    C  Y N 402 
PHE CE2    C  Y N 403 
PHE CZ     C  Y N 404 
PHE OXT    O  N N 405 
PHE H      H  N N 406 
PHE H2     H  N N 407 
PHE HA     H  N N 408 
PHE HB2    H  N N 409 
PHE HB3    H  N N 410 
PHE HD1    H  N N 411 
PHE HD2    H  N N 412 
PHE HE1    H  N N 413 
PHE HE2    H  N N 414 
PHE HZ     H  N N 415 
PHE HXT    H  N N 416 
PRO N      N  N N 417 
PRO CA     C  N S 418 
PRO C      C  N N 419 
PRO O      O  N N 420 
PRO CB     C  N N 421 
PRO CG     C  N N 422 
PRO CD     C  N N 423 
PRO OXT    O  N N 424 
PRO H      H  N N 425 
PRO HA     H  N N 426 
PRO HB2    H  N N 427 
PRO HB3    H  N N 428 
PRO HG2    H  N N 429 
PRO HG3    H  N N 430 
PRO HD2    H  N N 431 
PRO HD3    H  N N 432 
PRO HXT    H  N N 433 
SER N      N  N N 434 
SER CA     C  N S 435 
SER C      C  N N 436 
SER O      O  N N 437 
SER CB     C  N N 438 
SER OG     O  N N 439 
SER OXT    O  N N 440 
SER H      H  N N 441 
SER H2     H  N N 442 
SER HA     H  N N 443 
SER HB2    H  N N 444 
SER HB3    H  N N 445 
SER HG     H  N N 446 
SER HXT    H  N N 447 
THR N      N  N N 448 
THR CA     C  N S 449 
THR C      C  N N 450 
THR O      O  N N 451 
THR CB     C  N R 452 
THR OG1    O  N N 453 
THR CG2    C  N N 454 
THR OXT    O  N N 455 
THR H      H  N N 456 
THR H2     H  N N 457 
THR HA     H  N N 458 
THR HB     H  N N 459 
THR HG1    H  N N 460 
THR HG21   H  N N 461 
THR HG22   H  N N 462 
THR HG23   H  N N 463 
THR HXT    H  N N 464 
TRP N      N  N N 465 
TRP CA     C  N S 466 
TRP C      C  N N 467 
TRP O      O  N N 468 
TRP CB     C  N N 469 
TRP CG     C  Y N 470 
TRP CD1    C  Y N 471 
TRP CD2    C  Y N 472 
TRP NE1    N  Y N 473 
TRP CE2    C  Y N 474 
TRP CE3    C  Y N 475 
TRP CZ2    C  Y N 476 
TRP CZ3    C  Y N 477 
TRP CH2    C  Y N 478 
TRP OXT    O  N N 479 
TRP H      H  N N 480 
TRP H2     H  N N 481 
TRP HA     H  N N 482 
TRP HB2    H  N N 483 
TRP HB3    H  N N 484 
TRP HD1    H  N N 485 
TRP HE1    H  N N 486 
TRP HE3    H  N N 487 
TRP HZ2    H  N N 488 
TRP HZ3    H  N N 489 
TRP HH2    H  N N 490 
TRP HXT    H  N N 491 
TYR N      N  N N 492 
TYR CA     C  N S 493 
TYR C      C  N N 494 
TYR O      O  N N 495 
TYR CB     C  N N 496 
TYR CG     C  Y N 497 
TYR CD1    C  Y N 498 
TYR CD2    C  Y N 499 
TYR CE1    C  Y N 500 
TYR CE2    C  Y N 501 
TYR CZ     C  Y N 502 
TYR OH     O  N N 503 
TYR OXT    O  N N 504 
TYR H      H  N N 505 
TYR H2     H  N N 506 
TYR HA     H  N N 507 
TYR HB2    H  N N 508 
TYR HB3    H  N N 509 
TYR HD1    H  N N 510 
TYR HD2    H  N N 511 
TYR HE1    H  N N 512 
TYR HE2    H  N N 513 
TYR HH     H  N N 514 
TYR HXT    H  N N 515 
VAL N      N  N N 516 
VAL CA     C  N S 517 
VAL C      C  N N 518 
VAL O      O  N N 519 
VAL CB     C  N N 520 
VAL CG1    C  N N 521 
VAL CG2    C  N N 522 
VAL OXT    O  N N 523 
VAL H      H  N N 524 
VAL H2     H  N N 525 
VAL HA     H  N N 526 
VAL HB     H  N N 527 
VAL HG11   H  N N 528 
VAL HG12   H  N N 529 
VAL HG13   H  N N 530 
VAL HG21   H  N N 531 
VAL HG22   H  N N 532 
VAL HG23   H  N N 533 
VAL HXT    H  N N 534 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N     CA     sing N N 1   
ALA N     H      sing N N 2   
ALA N     H2     sing N N 3   
ALA CA    C      sing N N 4   
ALA CA    CB     sing N N 5   
ALA CA    HA     sing N N 6   
ALA C     O      doub N N 7   
ALA C     OXT    sing N N 8   
ALA CB    HB1    sing N N 9   
ALA CB    HB2    sing N N 10  
ALA CB    HB3    sing N N 11  
ALA OXT   HXT    sing N N 12  
ARG N     CA     sing N N 13  
ARG N     H      sing N N 14  
ARG N     H2     sing N N 15  
ARG CA    C      sing N N 16  
ARG CA    CB     sing N N 17  
ARG CA    HA     sing N N 18  
ARG C     O      doub N N 19  
ARG C     OXT    sing N N 20  
ARG CB    CG     sing N N 21  
ARG CB    HB2    sing N N 22  
ARG CB    HB3    sing N N 23  
ARG CG    CD     sing N N 24  
ARG CG    HG2    sing N N 25  
ARG CG    HG3    sing N N 26  
ARG CD    NE     sing N N 27  
ARG CD    HD2    sing N N 28  
ARG CD    HD3    sing N N 29  
ARG NE    CZ     sing N N 30  
ARG NE    HE     sing N N 31  
ARG CZ    NH1    sing N N 32  
ARG CZ    NH2    doub N N 33  
ARG NH1   HH11   sing N N 34  
ARG NH1   HH12   sing N N 35  
ARG NH2   HH21   sing N N 36  
ARG NH2   HH22   sing N N 37  
ARG OXT   HXT    sing N N 38  
ASN N     CA     sing N N 39  
ASN N     H      sing N N 40  
ASN N     H2     sing N N 41  
ASN CA    C      sing N N 42  
ASN CA    CB     sing N N 43  
ASN CA    HA     sing N N 44  
ASN C     O      doub N N 45  
ASN C     OXT    sing N N 46  
ASN CB    CG     sing N N 47  
ASN CB    HB2    sing N N 48  
ASN CB    HB3    sing N N 49  
ASN CG    OD1    doub N N 50  
ASN CG    ND2    sing N N 51  
ASN ND2   HD21   sing N N 52  
ASN ND2   HD22   sing N N 53  
ASN OXT   HXT    sing N N 54  
ASP N     CA     sing N N 55  
ASP N     H      sing N N 56  
ASP N     H2     sing N N 57  
ASP CA    C      sing N N 58  
ASP CA    CB     sing N N 59  
ASP CA    HA     sing N N 60  
ASP C     O      doub N N 61  
ASP C     OXT    sing N N 62  
ASP CB    CG     sing N N 63  
ASP CB    HB2    sing N N 64  
ASP CB    HB3    sing N N 65  
ASP CG    OD1    doub N N 66  
ASP CG    OD2    sing N N 67  
ASP OD2   HD2    sing N N 68  
ASP OXT   HXT    sing N N 69  
CYS N     CA     sing N N 70  
CYS N     H      sing N N 71  
CYS N     H2     sing N N 72  
CYS CA    C      sing N N 73  
CYS CA    CB     sing N N 74  
CYS CA    HA     sing N N 75  
CYS C     O      doub N N 76  
CYS C     OXT    sing N N 77  
CYS CB    SG     sing N N 78  
CYS CB    HB2    sing N N 79  
CYS CB    HB3    sing N N 80  
CYS SG    HG     sing N N 81  
CYS OXT   HXT    sing N N 82  
DA  OP3   P      sing N N 83  
DA  OP3   HOP3   sing N N 84  
DA  P     OP1    doub N N 85  
DA  P     OP2    sing N N 86  
DA  P     "O5'"  sing N N 87  
DA  OP2   HOP2   sing N N 88  
DA  "O5'" "C5'"  sing N N 89  
DA  "C5'" "C4'"  sing N N 90  
DA  "C5'" "H5'"  sing N N 91  
DA  "C5'" "H5''" sing N N 92  
DA  "C4'" "O4'"  sing N N 93  
DA  "C4'" "C3'"  sing N N 94  
DA  "C4'" "H4'"  sing N N 95  
DA  "O4'" "C1'"  sing N N 96  
DA  "C3'" "O3'"  sing N N 97  
DA  "C3'" "C2'"  sing N N 98  
DA  "C3'" "H3'"  sing N N 99  
DA  "O3'" "HO3'" sing N N 100 
DA  "C2'" "C1'"  sing N N 101 
DA  "C2'" "H2'"  sing N N 102 
DA  "C2'" "H2''" sing N N 103 
DA  "C1'" N9     sing N N 104 
DA  "C1'" "H1'"  sing N N 105 
DA  N9    C8     sing Y N 106 
DA  N9    C4     sing Y N 107 
DA  C8    N7     doub Y N 108 
DA  C8    H8     sing N N 109 
DA  N7    C5     sing Y N 110 
DA  C5    C6     sing Y N 111 
DA  C5    C4     doub Y N 112 
DA  C6    N6     sing N N 113 
DA  C6    N1     doub Y N 114 
DA  N6    H61    sing N N 115 
DA  N6    H62    sing N N 116 
DA  N1    C2     sing Y N 117 
DA  C2    N3     doub Y N 118 
DA  C2    H2     sing N N 119 
DA  N3    C4     sing Y N 120 
DC  OP3   P      sing N N 121 
DC  OP3   HOP3   sing N N 122 
DC  P     OP1    doub N N 123 
DC  P     OP2    sing N N 124 
DC  P     "O5'"  sing N N 125 
DC  OP2   HOP2   sing N N 126 
DC  "O5'" "C5'"  sing N N 127 
DC  "C5'" "C4'"  sing N N 128 
DC  "C5'" "H5'"  sing N N 129 
DC  "C5'" "H5''" sing N N 130 
DC  "C4'" "O4'"  sing N N 131 
DC  "C4'" "C3'"  sing N N 132 
DC  "C4'" "H4'"  sing N N 133 
DC  "O4'" "C1'"  sing N N 134 
DC  "C3'" "O3'"  sing N N 135 
DC  "C3'" "C2'"  sing N N 136 
DC  "C3'" "H3'"  sing N N 137 
DC  "O3'" "HO3'" sing N N 138 
DC  "C2'" "C1'"  sing N N 139 
DC  "C2'" "H2'"  sing N N 140 
DC  "C2'" "H2''" sing N N 141 
DC  "C1'" N1     sing N N 142 
DC  "C1'" "H1'"  sing N N 143 
DC  N1    C2     sing N N 144 
DC  N1    C6     sing N N 145 
DC  C2    O2     doub N N 146 
DC  C2    N3     sing N N 147 
DC  N3    C4     doub N N 148 
DC  C4    N4     sing N N 149 
DC  C4    C5     sing N N 150 
DC  N4    H41    sing N N 151 
DC  N4    H42    sing N N 152 
DC  C5    C6     doub N N 153 
DC  C5    H5     sing N N 154 
DC  C6    H6     sing N N 155 
DG  OP3   P      sing N N 156 
DG  OP3   HOP3   sing N N 157 
DG  P     OP1    doub N N 158 
DG  P     OP2    sing N N 159 
DG  P     "O5'"  sing N N 160 
DG  OP2   HOP2   sing N N 161 
DG  "O5'" "C5'"  sing N N 162 
DG  "C5'" "C4'"  sing N N 163 
DG  "C5'" "H5'"  sing N N 164 
DG  "C5'" "H5''" sing N N 165 
DG  "C4'" "O4'"  sing N N 166 
DG  "C4'" "C3'"  sing N N 167 
DG  "C4'" "H4'"  sing N N 168 
DG  "O4'" "C1'"  sing N N 169 
DG  "C3'" "O3'"  sing N N 170 
DG  "C3'" "C2'"  sing N N 171 
DG  "C3'" "H3'"  sing N N 172 
DG  "O3'" "HO3'" sing N N 173 
DG  "C2'" "C1'"  sing N N 174 
DG  "C2'" "H2'"  sing N N 175 
DG  "C2'" "H2''" sing N N 176 
DG  "C1'" N9     sing N N 177 
DG  "C1'" "H1'"  sing N N 178 
DG  N9    C8     sing Y N 179 
DG  N9    C4     sing Y N 180 
DG  C8    N7     doub Y N 181 
DG  C8    H8     sing N N 182 
DG  N7    C5     sing Y N 183 
DG  C5    C6     sing N N 184 
DG  C5    C4     doub Y N 185 
DG  C6    O6     doub N N 186 
DG  C6    N1     sing N N 187 
DG  N1    C2     sing N N 188 
DG  N1    H1     sing N N 189 
DG  C2    N2     sing N N 190 
DG  C2    N3     doub N N 191 
DG  N2    H21    sing N N 192 
DG  N2    H22    sing N N 193 
DG  N3    C4     sing N N 194 
DT  OP3   P      sing N N 195 
DT  OP3   HOP3   sing N N 196 
DT  P     OP1    doub N N 197 
DT  P     OP2    sing N N 198 
DT  P     "O5'"  sing N N 199 
DT  OP2   HOP2   sing N N 200 
DT  "O5'" "C5'"  sing N N 201 
DT  "C5'" "C4'"  sing N N 202 
DT  "C5'" "H5'"  sing N N 203 
DT  "C5'" "H5''" sing N N 204 
DT  "C4'" "O4'"  sing N N 205 
DT  "C4'" "C3'"  sing N N 206 
DT  "C4'" "H4'"  sing N N 207 
DT  "O4'" "C1'"  sing N N 208 
DT  "C3'" "O3'"  sing N N 209 
DT  "C3'" "C2'"  sing N N 210 
DT  "C3'" "H3'"  sing N N 211 
DT  "O3'" "HO3'" sing N N 212 
DT  "C2'" "C1'"  sing N N 213 
DT  "C2'" "H2'"  sing N N 214 
DT  "C2'" "H2''" sing N N 215 
DT  "C1'" N1     sing N N 216 
DT  "C1'" "H1'"  sing N N 217 
DT  N1    C2     sing N N 218 
DT  N1    C6     sing N N 219 
DT  C2    O2     doub N N 220 
DT  C2    N3     sing N N 221 
DT  N3    C4     sing N N 222 
DT  N3    H3     sing N N 223 
DT  C4    O4     doub N N 224 
DT  C4    C5     sing N N 225 
DT  C5    C7     sing N N 226 
DT  C5    C6     doub N N 227 
DT  C7    H71    sing N N 228 
DT  C7    H72    sing N N 229 
DT  C7    H73    sing N N 230 
DT  C6    H6     sing N N 231 
GLN N     CA     sing N N 232 
GLN N     H      sing N N 233 
GLN N     H2     sing N N 234 
GLN CA    C      sing N N 235 
GLN CA    CB     sing N N 236 
GLN CA    HA     sing N N 237 
GLN C     O      doub N N 238 
GLN C     OXT    sing N N 239 
GLN CB    CG     sing N N 240 
GLN CB    HB2    sing N N 241 
GLN CB    HB3    sing N N 242 
GLN CG    CD     sing N N 243 
GLN CG    HG2    sing N N 244 
GLN CG    HG3    sing N N 245 
GLN CD    OE1    doub N N 246 
GLN CD    NE2    sing N N 247 
GLN NE2   HE21   sing N N 248 
GLN NE2   HE22   sing N N 249 
GLN OXT   HXT    sing N N 250 
GLU N     CA     sing N N 251 
GLU N     H      sing N N 252 
GLU N     H2     sing N N 253 
GLU CA    C      sing N N 254 
GLU CA    CB     sing N N 255 
GLU CA    HA     sing N N 256 
GLU C     O      doub N N 257 
GLU C     OXT    sing N N 258 
GLU CB    CG     sing N N 259 
GLU CB    HB2    sing N N 260 
GLU CB    HB3    sing N N 261 
GLU CG    CD     sing N N 262 
GLU CG    HG2    sing N N 263 
GLU CG    HG3    sing N N 264 
GLU CD    OE1    doub N N 265 
GLU CD    OE2    sing N N 266 
GLU OE2   HE2    sing N N 267 
GLU OXT   HXT    sing N N 268 
GLY N     CA     sing N N 269 
GLY N     H      sing N N 270 
GLY N     H2     sing N N 271 
GLY CA    C      sing N N 272 
GLY CA    HA2    sing N N 273 
GLY CA    HA3    sing N N 274 
GLY C     O      doub N N 275 
GLY C     OXT    sing N N 276 
GLY OXT   HXT    sing N N 277 
HIS N     CA     sing N N 278 
HIS N     H      sing N N 279 
HIS N     H2     sing N N 280 
HIS CA    C      sing N N 281 
HIS CA    CB     sing N N 282 
HIS CA    HA     sing N N 283 
HIS C     O      doub N N 284 
HIS C     OXT    sing N N 285 
HIS CB    CG     sing N N 286 
HIS CB    HB2    sing N N 287 
HIS CB    HB3    sing N N 288 
HIS CG    ND1    sing Y N 289 
HIS CG    CD2    doub Y N 290 
HIS ND1   CE1    doub Y N 291 
HIS ND1   HD1    sing N N 292 
HIS CD2   NE2    sing Y N 293 
HIS CD2   HD2    sing N N 294 
HIS CE1   NE2    sing Y N 295 
HIS CE1   HE1    sing N N 296 
HIS NE2   HE2    sing N N 297 
HIS OXT   HXT    sing N N 298 
HOH O     H1     sing N N 299 
HOH O     H2     sing N N 300 
ILE N     CA     sing N N 301 
ILE N     H      sing N N 302 
ILE N     H2     sing N N 303 
ILE CA    C      sing N N 304 
ILE CA    CB     sing N N 305 
ILE CA    HA     sing N N 306 
ILE C     O      doub N N 307 
ILE C     OXT    sing N N 308 
ILE CB    CG1    sing N N 309 
ILE CB    CG2    sing N N 310 
ILE CB    HB     sing N N 311 
ILE CG1   CD1    sing N N 312 
ILE CG1   HG12   sing N N 313 
ILE CG1   HG13   sing N N 314 
ILE CG2   HG21   sing N N 315 
ILE CG2   HG22   sing N N 316 
ILE CG2   HG23   sing N N 317 
ILE CD1   HD11   sing N N 318 
ILE CD1   HD12   sing N N 319 
ILE CD1   HD13   sing N N 320 
ILE OXT   HXT    sing N N 321 
LEU N     CA     sing N N 322 
LEU N     H      sing N N 323 
LEU N     H2     sing N N 324 
LEU CA    C      sing N N 325 
LEU CA    CB     sing N N 326 
LEU CA    HA     sing N N 327 
LEU C     O      doub N N 328 
LEU C     OXT    sing N N 329 
LEU CB    CG     sing N N 330 
LEU CB    HB2    sing N N 331 
LEU CB    HB3    sing N N 332 
LEU CG    CD1    sing N N 333 
LEU CG    CD2    sing N N 334 
LEU CG    HG     sing N N 335 
LEU CD1   HD11   sing N N 336 
LEU CD1   HD12   sing N N 337 
LEU CD1   HD13   sing N N 338 
LEU CD2   HD21   sing N N 339 
LEU CD2   HD22   sing N N 340 
LEU CD2   HD23   sing N N 341 
LEU OXT   HXT    sing N N 342 
LYS N     CA     sing N N 343 
LYS N     H      sing N N 344 
LYS N     H2     sing N N 345 
LYS CA    C      sing N N 346 
LYS CA    CB     sing N N 347 
LYS CA    HA     sing N N 348 
LYS C     O      doub N N 349 
LYS C     OXT    sing N N 350 
LYS CB    CG     sing N N 351 
LYS CB    HB2    sing N N 352 
LYS CB    HB3    sing N N 353 
LYS CG    CD     sing N N 354 
LYS CG    HG2    sing N N 355 
LYS CG    HG3    sing N N 356 
LYS CD    CE     sing N N 357 
LYS CD    HD2    sing N N 358 
LYS CD    HD3    sing N N 359 
LYS CE    NZ     sing N N 360 
LYS CE    HE2    sing N N 361 
LYS CE    HE3    sing N N 362 
LYS NZ    HZ1    sing N N 363 
LYS NZ    HZ2    sing N N 364 
LYS NZ    HZ3    sing N N 365 
LYS OXT   HXT    sing N N 366 
MET N     CA     sing N N 367 
MET N     H      sing N N 368 
MET N     H2     sing N N 369 
MET CA    C      sing N N 370 
MET CA    CB     sing N N 371 
MET CA    HA     sing N N 372 
MET C     O      doub N N 373 
MET C     OXT    sing N N 374 
MET CB    CG     sing N N 375 
MET CB    HB2    sing N N 376 
MET CB    HB3    sing N N 377 
MET CG    SD     sing N N 378 
MET CG    HG2    sing N N 379 
MET CG    HG3    sing N N 380 
MET SD    CE     sing N N 381 
MET CE    HE1    sing N N 382 
MET CE    HE2    sing N N 383 
MET CE    HE3    sing N N 384 
MET OXT   HXT    sing N N 385 
PHE N     CA     sing N N 386 
PHE N     H      sing N N 387 
PHE N     H2     sing N N 388 
PHE CA    C      sing N N 389 
PHE CA    CB     sing N N 390 
PHE CA    HA     sing N N 391 
PHE C     O      doub N N 392 
PHE C     OXT    sing N N 393 
PHE CB    CG     sing N N 394 
PHE CB    HB2    sing N N 395 
PHE CB    HB3    sing N N 396 
PHE CG    CD1    doub Y N 397 
PHE CG    CD2    sing Y N 398 
PHE CD1   CE1    sing Y N 399 
PHE CD1   HD1    sing N N 400 
PHE CD2   CE2    doub Y N 401 
PHE CD2   HD2    sing N N 402 
PHE CE1   CZ     doub Y N 403 
PHE CE1   HE1    sing N N 404 
PHE CE2   CZ     sing Y N 405 
PHE CE2   HE2    sing N N 406 
PHE CZ    HZ     sing N N 407 
PHE OXT   HXT    sing N N 408 
PRO N     CA     sing N N 409 
PRO N     CD     sing N N 410 
PRO N     H      sing N N 411 
PRO CA    C      sing N N 412 
PRO CA    CB     sing N N 413 
PRO CA    HA     sing N N 414 
PRO C     O      doub N N 415 
PRO C     OXT    sing N N 416 
PRO CB    CG     sing N N 417 
PRO CB    HB2    sing N N 418 
PRO CB    HB3    sing N N 419 
PRO CG    CD     sing N N 420 
PRO CG    HG2    sing N N 421 
PRO CG    HG3    sing N N 422 
PRO CD    HD2    sing N N 423 
PRO CD    HD3    sing N N 424 
PRO OXT   HXT    sing N N 425 
SER N     CA     sing N N 426 
SER N     H      sing N N 427 
SER N     H2     sing N N 428 
SER CA    C      sing N N 429 
SER CA    CB     sing N N 430 
SER CA    HA     sing N N 431 
SER C     O      doub N N 432 
SER C     OXT    sing N N 433 
SER CB    OG     sing N N 434 
SER CB    HB2    sing N N 435 
SER CB    HB3    sing N N 436 
SER OG    HG     sing N N 437 
SER OXT   HXT    sing N N 438 
THR N     CA     sing N N 439 
THR N     H      sing N N 440 
THR N     H2     sing N N 441 
THR CA    C      sing N N 442 
THR CA    CB     sing N N 443 
THR CA    HA     sing N N 444 
THR C     O      doub N N 445 
THR C     OXT    sing N N 446 
THR CB    OG1    sing N N 447 
THR CB    CG2    sing N N 448 
THR CB    HB     sing N N 449 
THR OG1   HG1    sing N N 450 
THR CG2   HG21   sing N N 451 
THR CG2   HG22   sing N N 452 
THR CG2   HG23   sing N N 453 
THR OXT   HXT    sing N N 454 
TRP N     CA     sing N N 455 
TRP N     H      sing N N 456 
TRP N     H2     sing N N 457 
TRP CA    C      sing N N 458 
TRP CA    CB     sing N N 459 
TRP CA    HA     sing N N 460 
TRP C     O      doub N N 461 
TRP C     OXT    sing N N 462 
TRP CB    CG     sing N N 463 
TRP CB    HB2    sing N N 464 
TRP CB    HB3    sing N N 465 
TRP CG    CD1    doub Y N 466 
TRP CG    CD2    sing Y N 467 
TRP CD1   NE1    sing Y N 468 
TRP CD1   HD1    sing N N 469 
TRP CD2   CE2    doub Y N 470 
TRP CD2   CE3    sing Y N 471 
TRP NE1   CE2    sing Y N 472 
TRP NE1   HE1    sing N N 473 
TRP CE2   CZ2    sing Y N 474 
TRP CE3   CZ3    doub Y N 475 
TRP CE3   HE3    sing N N 476 
TRP CZ2   CH2    doub Y N 477 
TRP CZ2   HZ2    sing N N 478 
TRP CZ3   CH2    sing Y N 479 
TRP CZ3   HZ3    sing N N 480 
TRP CH2   HH2    sing N N 481 
TRP OXT   HXT    sing N N 482 
TYR N     CA     sing N N 483 
TYR N     H      sing N N 484 
TYR N     H2     sing N N 485 
TYR CA    C      sing N N 486 
TYR CA    CB     sing N N 487 
TYR CA    HA     sing N N 488 
TYR C     O      doub N N 489 
TYR C     OXT    sing N N 490 
TYR CB    CG     sing N N 491 
TYR CB    HB2    sing N N 492 
TYR CB    HB3    sing N N 493 
TYR CG    CD1    doub Y N 494 
TYR CG    CD2    sing Y N 495 
TYR CD1   CE1    sing Y N 496 
TYR CD1   HD1    sing N N 497 
TYR CD2   CE2    doub Y N 498 
TYR CD2   HD2    sing N N 499 
TYR CE1   CZ     doub Y N 500 
TYR CE1   HE1    sing N N 501 
TYR CE2   CZ     sing Y N 502 
TYR CE2   HE2    sing N N 503 
TYR CZ    OH     sing N N 504 
TYR OH    HH     sing N N 505 
TYR OXT   HXT    sing N N 506 
VAL N     CA     sing N N 507 
VAL N     H      sing N N 508 
VAL N     H2     sing N N 509 
VAL CA    C      sing N N 510 
VAL CA    CB     sing N N 511 
VAL CA    HA     sing N N 512 
VAL C     O      doub N N 513 
VAL C     OXT    sing N N 514 
VAL CB    CG1    sing N N 515 
VAL CB    CG2    sing N N 516 
VAL CB    HB     sing N N 517 
VAL CG1   HG11   sing N N 518 
VAL CG1   HG12   sing N N 519 
VAL CG1   HG13   sing N N 520 
VAL CG2   HG21   sing N N 521 
VAL CG2   HG22   sing N N 522 
VAL CG2   HG23   sing N N 523 
VAL OXT   HXT    sing N N 524 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-18 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BGJ 
_em_admin.last_update        2025-03-05 
_em_admin.map_release_date   2025-03-05 
_em_admin.title              'SgrAI mutant K242A endonuclease DNA-bound dimer with Mg2+ and intact primary site DNA' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 25  mM ?     1 Tris-HCl             
1 150 mM NaCl  2 'sodium chloride'    
1 1   mM ?     3 TCEP                 
1 8.7 mM MgCl2 4 'Magnesium chloride' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                KILODALTONS/NANOMETER 
_em_entity_assembly_molwt.value                33.6 
# 
_em_helical_entity.id                             1 
_em_helical_entity.image_processing_id            1 
_em_helical_entity.details                        ? 
_em_helical_entity.axial_symmetry                 C2 
_em_helical_entity.angular_rotation_per_subunit   -86.2 
_em_helical_entity.axial_rise_per_subunit         20.9 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         42.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       COUNTING 
_em_image_recording.film_or_detector_model              'GATAN K3 (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     3488 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?         ?   
'IMAGE ACQUISITION'             ? 2  ? ? 1 Leginon   ?   
MASKING                         ? 3  ? ? ? ?         ?   
'CTF CORRECTION'                ? 4  1 ? ? cryoSPARC ?   
'LAYERLINE INDEXING'            ? 5  ? ? ? ?         ?   
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?         ?   
'MODEL FITTING'                 ? 7  ? 1 ? Coot      ?   
OTHER                           ? 8  ? ? ? ?         ?   
'INITIAL EULER ASSIGNMENT'      ? 9  1 ? ? cryoSPARC ?   
'FINAL EULER ASSIGNMENT'        ? 10 1 ? ? RELION    4.2 
CLASSIFICATION                  ? 11 1 ? ? ?         ?   
RECONSTRUCTION                  ? 12 1 ? ? cryoSPARC 4.2 
'MODEL REFINEMENT'              ? 13 ? 1 ? PHENIX    ?   
'VOLUME SELECTION'              ? 14 1 1 1 ?         ?   
'SERIES ALIGNMENT'              ? 15 1 1 1 ?         ?   
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?         ?   
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?         ?   
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?         ?   
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?         ?   
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_ndb_struct_conf_na.entry_id 
_ndb_struct_conf_na.feature 
9BGJ 'double helix'        
9BGJ 'b-form double helix' 
# 
loop_
_ndb_struct_na_base_pair.model_number 
_ndb_struct_na_base_pair.i_label_asym_id 
_ndb_struct_na_base_pair.i_label_comp_id 
_ndb_struct_na_base_pair.i_label_seq_id 
_ndb_struct_na_base_pair.i_symmetry 
_ndb_struct_na_base_pair.j_label_asym_id 
_ndb_struct_na_base_pair.j_label_comp_id 
_ndb_struct_na_base_pair.j_label_seq_id 
_ndb_struct_na_base_pair.j_symmetry 
_ndb_struct_na_base_pair.shear 
_ndb_struct_na_base_pair.stretch 
_ndb_struct_na_base_pair.stagger 
_ndb_struct_na_base_pair.buckle 
_ndb_struct_na_base_pair.propeller 
_ndb_struct_na_base_pair.opening 
_ndb_struct_na_base_pair.pair_number 
_ndb_struct_na_base_pair.pair_name 
_ndb_struct_na_base_pair.i_auth_asym_id 
_ndb_struct_na_base_pair.i_auth_seq_id 
_ndb_struct_na_base_pair.i_PDB_ins_code 
_ndb_struct_na_base_pair.j_auth_asym_id 
_ndb_struct_na_base_pair.j_auth_seq_id 
_ndb_struct_na_base_pair.j_PDB_ins_code 
_ndb_struct_na_base_pair.hbond_type_28 
_ndb_struct_na_base_pair.hbond_type_12 
1 B DG 9  1_555 D DC 72 1_555 -0.193 -0.289 -1.175 -9.837  -4.313  1.634  1  C_DG2:DC25_D  C 2  ? D 25 ? 19 1 
1 B DG 10 1_555 D DC 71 1_555 -0.120 -0.361 -1.346 -10.809 0.325   -1.780 2  C_DG3:DC24_D  C 3  ? D 24 ? 19 1 
1 B DT 11 1_555 D DA 70 1_555 -0.127 -0.155 -0.812 -0.771  -1.324  -2.965 3  C_DT4:DA23_D  C 4  ? D 23 ? 20 1 
1 B DC 12 1_555 D DG 69 1_555 0.193  -0.164 -0.543 2.724   -3.157  0.135  4  C_DC5:DG22_D  C 5  ? D 22 ? 19 1 
1 B DT 13 1_555 D DA 68 1_555 -0.109 -0.083 -0.064 0.183   -8.249  -1.472 5  C_DT6:DA21_D  C 6  ? D 21 ? 20 1 
1 B DT 14 1_555 D DA 67 1_555 -0.161 -0.102 0.171  -0.924  -7.863  -0.817 6  C_DT7:DA20_D  C 7  ? D 20 ? 20 1 
1 B DC 15 1_555 D DG 66 1_555 0.179  -0.161 0.356  -1.734  -5.947  -0.943 7  C_DC8:DG19_D  C 8  ? D 19 ? 19 1 
1 B DA 16 1_555 D DT 65 1_555 -0.003 0.379  0.600  -5.635  -5.783  5.858  8  C_DA9:DT18_D  C 9  ? D 18 ? 20 1 
1 B DC 17 1_555 D DG 64 1_555 0.196  -0.157 0.015  -5.394  1.426   -0.491 9  C_DC10:DG17_D C 10 ? D 17 ? 19 1 
1 B DA 18 1_555 D DT 63 1_555 0.071  -0.133 0.166  -2.485  -0.791  0.623  10 C_DA11:DT16_D C 11 ? D 16 ? 20 1 
1 B DC 19 1_555 D DG 62 1_555 0.211  -0.171 -0.246 -3.775  -1.070  1.255  11 C_DC12:DG15_D C 12 ? D 15 ? 19 1 
1 B DC 20 1_555 D DG 61 1_555 0.178  -0.163 -0.195 1.122   2.113   -0.579 12 C_DC13:DG14_D C 13 ? D 14 ? 19 1 
1 B DG 21 1_555 D DC 60 1_555 -0.181 -0.159 -0.234 -2.978  2.813   -0.487 13 C_DG14:DC13_D C 14 ? D 13 ? 19 1 
1 B DG 22 1_555 D DC 59 1_555 -0.208 -0.171 -0.035 2.074   1.645   0.833  14 C_DG15:DC12_D C 15 ? D 12 ? 19 1 
1 B DT 23 1_555 D DA 58 1_555 -0.058 -0.172 0.382  -0.212  3.843   1.378  15 C_DT16:DA11_D C 16 ? D 11 ? 20 1 
1 B DG 24 1_555 D DC 57 1_555 -0.178 -0.209 0.547  3.460   1.126   -0.578 16 C_DG17:DC10_D C 17 ? D 10 ? 19 1 
1 B DG 25 1_555 D DC 56 1_555 -0.151 -0.260 0.867  2.395   -4.965  -2.039 17 C_DG18:DC9_D  C 18 ? D 9  ? 19 1 
1 B DA 26 1_555 D DT 55 1_555 0.673  0.797  0.550  0.643   -12.142 0.232  18 C_DA19:DT8_D  C 19 ? D 8  ? ?  ? 
1 B DT 27 1_555 D DA 54 1_555 -0.056 -0.105 -0.157 1.183   -9.169  1.362  19 C_DT20:DA7_D  C 20 ? D 7  ? 20 1 
1 B DC 29 1_555 D DG 52 1_555 0.179  -0.127 0.043  -14.360 -10.714 3.198  20 C_DC22:DG5_D  C 22 ? D 5  ? 19 1 
1 B DG 30 1_555 D DC 51 1_555 -1.674 0.669  -0.682 -15.136 -16.876 8.580  21 C_DG23:DC4_D  C 23 ? D 4  ? ?  ? 
1 B DT 31 1_555 D DA 50 1_555 0.493  -0.005 0.133  16.452  -17.826 14.042 22 C_DT24:DA3_D  C 24 ? D 3  ? 20 1 
1 B DG 32 1_555 D DC 49 1_555 -0.246 -0.182 -0.124 13.279  -13.868 5.198  23 C_DG25:DC2_D  C 25 ? D 2  ? 19 1 
# 
loop_
_ndb_struct_na_base_pair_step.model_number 
_ndb_struct_na_base_pair_step.i_label_asym_id_1 
_ndb_struct_na_base_pair_step.i_label_comp_id_1 
_ndb_struct_na_base_pair_step.i_label_seq_id_1 
_ndb_struct_na_base_pair_step.i_symmetry_1 
_ndb_struct_na_base_pair_step.j_label_asym_id_1 
_ndb_struct_na_base_pair_step.j_label_comp_id_1 
_ndb_struct_na_base_pair_step.j_label_seq_id_1 
_ndb_struct_na_base_pair_step.j_symmetry_1 
_ndb_struct_na_base_pair_step.i_label_asym_id_2 
_ndb_struct_na_base_pair_step.i_label_comp_id_2 
_ndb_struct_na_base_pair_step.i_label_seq_id_2 
_ndb_struct_na_base_pair_step.i_symmetry_2 
_ndb_struct_na_base_pair_step.j_label_asym_id_2 
_ndb_struct_na_base_pair_step.j_label_comp_id_2 
_ndb_struct_na_base_pair_step.j_label_seq_id_2 
_ndb_struct_na_base_pair_step.j_symmetry_2 
_ndb_struct_na_base_pair_step.shift 
_ndb_struct_na_base_pair_step.slide 
_ndb_struct_na_base_pair_step.rise 
_ndb_struct_na_base_pair_step.tilt 
_ndb_struct_na_base_pair_step.roll 
_ndb_struct_na_base_pair_step.twist 
_ndb_struct_na_base_pair_step.x_displacement 
_ndb_struct_na_base_pair_step.y_displacement 
_ndb_struct_na_base_pair_step.helical_rise 
_ndb_struct_na_base_pair_step.inclination 
_ndb_struct_na_base_pair_step.tip 
_ndb_struct_na_base_pair_step.helical_twist 
_ndb_struct_na_base_pair_step.step_number 
_ndb_struct_na_base_pair_step.step_name 
_ndb_struct_na_base_pair_step.i_auth_asym_id_1 
_ndb_struct_na_base_pair_step.i_auth_seq_id_1 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.j_auth_asym_id_1 
_ndb_struct_na_base_pair_step.j_auth_seq_id_1 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_1 
_ndb_struct_na_base_pair_step.i_auth_asym_id_2 
_ndb_struct_na_base_pair_step.i_auth_seq_id_2 
_ndb_struct_na_base_pair_step.i_PDB_ins_code_2 
_ndb_struct_na_base_pair_step.j_auth_asym_id_2 
_ndb_struct_na_base_pair_step.j_auth_seq_id_2 
_ndb_struct_na_base_pair_step.j_PDB_ins_code_2 
1 B DG 9  1_555 D DC 72 1_555 B DG 10 1_555 D DC 71 1_555 -0.721 2.347  3.258 -1.968  -0.415 38.188 3.635  0.854  3.265 -0.633 
3.006  38.239 1  CC_DG2DG3:DC24DC25_DD   C 2  ? D 25 ? C 3  ? D 24 ? 
1 B DG 10 1_555 D DC 71 1_555 B DT 11 1_555 D DA 70 1_555 -0.617 1.021  3.091 -5.221  5.105  25.094 0.876  -0.051 3.289 11.444 
11.704 26.118 2  CC_DG3DT4:DA23DC24_DD   C 3  ? D 24 ? C 4  ? D 23 ? 
1 B DT 11 1_555 D DA 70 1_555 B DC 12 1_555 D DG 69 1_555 0.553  -0.555 3.103 -1.109  4.489  38.916 -1.331 -0.950 3.007 6.709  
1.657  39.179 3  CC_DT4DC5:DG22DA23_DD   C 4  ? D 23 ? C 5  ? D 22 ? 
1 B DC 12 1_555 D DG 69 1_555 B DT 13 1_555 D DA 68 1_555 0.465  0.294  3.314 1.812   0.345  37.386 0.412  -0.483 3.334 0.537  
-2.824 37.430 4  CC_DC5DT6:DA21DG22_DD   C 5  ? D 22 ? C 6  ? D 21 ? 
1 B DT 13 1_555 D DA 68 1_555 B DT 14 1_555 D DA 67 1_555 -0.059 -0.386 3.294 -0.029  0.940  36.293 -0.752 0.091  3.283 1.508  
0.046  36.304 5  CC_DT6DT7:DA20DA21_DD   C 6  ? D 21 ? C 7  ? D 20 ? 
1 B DT 14 1_555 D DA 67 1_555 B DC 15 1_555 D DG 66 1_555 0.085  0.486  3.373 -1.646  0.549  38.774 0.663  -0.335 3.373 0.826  
2.478  38.811 6  CC_DT7DC8:DG19DA20_DD   C 7  ? D 20 ? C 8  ? D 19 ? 
1 B DC 15 1_555 D DG 66 1_555 B DA 16 1_555 D DT 65 1_555 0.269  0.990  3.610 -1.285  0.346  38.489 1.453  -0.583 3.608 0.524  
1.949  38.511 7  CC_DC8DA9:DT18DG19_DD   C 8  ? D 19 ? C 9  ? D 18 ? 
1 B DA 16 1_555 D DT 65 1_555 B DC 17 1_555 D DG 64 1_555 -0.979 0.053  3.461 -1.240  2.760  35.382 -0.342 1.412  3.486 4.532  
2.035  35.507 8  CC_DA9DC10:DG17DT18_DD  C 9  ? D 18 ? C 10 ? D 17 ? 
1 B DC 17 1_555 D DG 64 1_555 B DA 18 1_555 D DT 63 1_555 0.760  0.890  3.697 -1.432  7.982  33.792 0.077  -1.527 3.769 13.491 
2.421  34.724 9  CC_DC10DA11:DT16DG17_DD C 10 ? D 17 ? C 11 ? D 16 ? 
1 B DA 18 1_555 D DT 63 1_555 B DC 19 1_555 D DG 62 1_555 -0.656 -1.492 3.533 -1.404  3.512  31.838 -3.372 0.921  3.378 6.373  
2.548  32.056 10 CC_DA11DC12:DG15DT16_DD C 11 ? D 16 ? C 12 ? D 15 ? 
1 B DC 19 1_555 D DG 62 1_555 B DC 20 1_555 D DG 61 1_555 0.564  0.590  3.789 2.816   4.405  28.258 0.020  -0.389 3.871 8.927  
-5.706 28.728 11 CC_DC12DC13:DG14DG15_DD C 12 ? D 15 ? C 13 ? D 14 ? 
1 B DC 20 1_555 D DG 61 1_555 B DG 21 1_555 D DC 60 1_555 0.051  1.154  4.330 0.018   -1.958 35.358 2.275  -0.081 4.262 -3.220 
-0.030 35.411 12 CC_DC13DG14:DC13DG14_DD C 13 ? D 14 ? C 14 ? D 13 ? 
1 B DG 21 1_555 D DC 60 1_555 B DG 22 1_555 D DC 59 1_555 -0.619 0.490  3.700 -5.126  5.552  28.122 -0.440 -0.074 3.777 11.173 
10.315 29.100 13 CC_DG14DG15:DC12DC13_DD C 14 ? D 13 ? C 15 ? D 12 ? 
1 B DG 22 1_555 D DC 59 1_555 B DT 23 1_555 D DA 58 1_555 0.597  -1.518 3.539 0.818   3.665  33.326 -3.269 -0.892 3.371 6.366  
-1.420 33.531 14 CC_DG15DT16:DA11DC12_DD C 15 ? D 12 ? C 16 ? D 11 ? 
1 B DT 23 1_555 D DA 58 1_555 B DG 24 1_555 D DC 57 1_555 -0.938 0.727  3.761 -1.341  4.546  34.158 0.401  1.338  3.855 7.693  
2.269  34.476 15 CC_DT16DG17:DC10DA11_DD C 16 ? D 11 ? C 17 ? D 10 ? 
1 B DG 24 1_555 D DC 57 1_555 B DG 25 1_555 D DC 56 1_555 0.465  -0.193 3.485 1.145   2.078  35.106 -0.650 -0.587 3.481 3.441  
-1.896 35.184 16 CC_DG17DG18:DC9DC10_DD  C 17 ? D 10 ? C 18 ? D 9  ? 
1 B DG 25 1_555 D DC 56 1_555 B DA 26 1_555 D DT 55 1_555 -0.323 0.714  3.490 1.494   -0.338 42.938 1.011  0.599  3.472 -0.462 
-2.041 42.964 17 CC_DG18DA19:DT8DC9_DD   C 18 ? D 9  ? C 19 ? D 8  ? 
1 B DA 26 1_555 D DT 55 1_555 B DT 27 1_555 D DA 54 1_555 0.294  -0.221 3.422 2.308   0.822  29.292 -0.621 -0.060 3.427 1.622  
-4.555 29.392 18 CC_DA19DT20:DA7DT8_DD   C 19 ? D 8  ? C 20 ? D 7  ? 
1 B DT 27 1_555 D DA 54 1_555 B DC 29 1_555 D DG 52 1_555 -0.231 1.130  6.538 -2.571  3.142  77.532 0.723  0.038  6.577 2.508  
2.052  77.622 19 CC_DT20DC22:DG5DA7_DD   C 20 ? D 7  ? C 22 ? D 5  ? 
1 B DC 29 1_555 D DG 52 1_555 B DG 30 1_555 D DC 51 1_555 -0.835 0.172  3.232 -7.124  9.972  31.533 -1.361 0.252  3.244 17.543 
12.533 33.774 20 CC_DC22DG23:DC4DG5_DD   C 22 ? D 5  ? C 23 ? D 4  ? 
1 B DG 30 1_555 D DC 51 1_555 B DT 31 1_555 D DA 50 1_555 0.313  2.535  2.582 -10.906 0.891  44.522 3.198  -1.149 2.491 1.156  
14.141 45.780 21 CC_DG23DT24:DA3DC4_DD   C 23 ? D 4  ? C 24 ? D 3  ? 
1 B DT 31 1_555 D DA 50 1_555 B DG 32 1_555 D DC 49 1_555 -1.455 0.836  3.223 2.102   5.256  32.708 0.589  2.898  3.218 9.247  
-3.697 33.181 22 CC_DT24DG25:DC2DA3_DD   C 24 ? D 3  ? C 25 ? D 2  ? 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Science Foundation (NSF, United States)' 'United States' MCB-1934291 1 
'National Science Foundation (NSF, United States)' 'United States' DBI-2018942 2 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   6OBJ 
_pdbx_initial_refinement_model.details          ? 
# 
_atom_sites.entry_id                    9BGJ 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
MG 
N  
O  
P  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N     . PRO A 1 2   ? 118.807 122.378 172.123 1.00 66.48  ? 2   PRO A N     1 
ATOM   2    C  CA    . PRO A 1 2   ? 117.566 123.084 172.452 1.00 71.41  ? 2   PRO A CA    1 
ATOM   3    C  C     . PRO A 1 2   ? 116.741 123.381 171.211 1.00 67.90  ? 2   PRO A C     1 
ATOM   4    O  O     . PRO A 1 2   ? 117.226 123.173 170.102 1.00 67.02  ? 2   PRO A O     1 
ATOM   5    C  CB    . PRO A 1 2   ? 118.059 124.381 173.102 1.00 70.55  ? 2   PRO A CB    1 
ATOM   6    C  CG    . PRO A 1 2   ? 119.443 124.080 173.554 1.00 73.93  ? 2   PRO A CG    1 
ATOM   7    C  CD    . PRO A 1 2   ? 119.994 123.144 172.530 1.00 68.58  ? 2   PRO A CD    1 
ATOM   8    N  N     . PHE A 1 3   ? 115.508 123.855 171.399 1.00 65.99  ? 3   PHE A N     1 
ATOM   9    C  CA    . PHE A 1 3   ? 114.660 124.189 170.260 1.00 58.38  ? 3   PHE A CA    1 
ATOM   10   C  C     . PHE A 1 3   ? 115.287 125.298 169.425 1.00 62.09  ? 3   PHE A C     1 
ATOM   11   O  O     . PHE A 1 3   ? 115.645 125.092 168.260 1.00 67.95  ? 3   PHE A O     1 
ATOM   12   C  CB    . PHE A 1 3   ? 113.269 124.591 170.747 1.00 50.90  ? 3   PHE A CB    1 
ATOM   13   C  CG    . PHE A 1 3   ? 112.239 124.638 169.660 1.00 52.66  ? 3   PHE A CG    1 
ATOM   14   C  CD1   . PHE A 1 3   ? 112.004 123.532 168.866 1.00 54.02  ? 3   PHE A CD1   1 
ATOM   15   C  CD2   . PHE A 1 3   ? 111.503 125.785 169.437 1.00 57.05  ? 3   PHE A CD2   1 
ATOM   16   C  CE1   . PHE A 1 3   ? 111.056 123.572 167.867 1.00 58.27  ? 3   PHE A CE1   1 
ATOM   17   C  CE2   . PHE A 1 3   ? 110.555 125.828 168.440 1.00 57.36  ? 3   PHE A CE2   1 
ATOM   18   C  CZ    . PHE A 1 3   ? 110.331 124.721 167.654 1.00 56.04  ? 3   PHE A CZ    1 
ATOM   19   N  N     . THR A 1 4   ? 115.435 126.482 170.008 1.00 56.65  ? 4   THR A N     1 
ATOM   20   C  CA    . THR A 1 4   ? 116.175 127.545 169.348 1.00 56.03  ? 4   THR A CA    1 
ATOM   21   C  C     . THR A 1 4   ? 117.667 127.244 169.392 1.00 58.02  ? 4   THR A C     1 
ATOM   22   O  O     . THR A 1 4   ? 118.179 126.676 170.359 1.00 63.18  ? 4   THR A O     1 
ATOM   23   C  CB    . THR A 1 4   ? 115.888 128.891 170.008 1.00 59.19  ? 4   THR A CB    1 
ATOM   24   O  OG1   . THR A 1 4   ? 115.724 128.706 171.419 1.00 67.21  ? 4   THR A OG1   1 
ATOM   25   C  CG2   . THR A 1 4   ? 114.624 129.505 169.431 1.00 57.63  ? 4   THR A CG2   1 
ATOM   26   N  N     . TYR A 1 5   ? 118.365 127.621 168.324 1.00 58.69  ? 5   TYR A N     1 
ATOM   27   C  CA    . TYR A 1 5   ? 119.785 127.316 168.220 1.00 62.72  ? 5   TYR A CA    1 
ATOM   28   C  C     . TYR A 1 5   ? 120.570 128.021 169.318 1.00 68.22  ? 5   TYR A C     1 
ATOM   29   O  O     . TYR A 1 5   ? 120.369 129.211 169.578 1.00 66.96  ? 5   TYR A O     1 
ATOM   30   C  CB    . TYR A 1 5   ? 120.317 127.726 166.849 1.00 60.90  ? 5   TYR A CB    1 
ATOM   31   C  CG    . TYR A 1 5   ? 121.748 127.308 166.615 1.00 62.05  ? 5   TYR A CG    1 
ATOM   32   C  CD1   . TYR A 1 5   ? 122.126 125.980 166.718 1.00 59.17  ? 5   TYR A CD1   1 
ATOM   33   C  CD2   . TYR A 1 5   ? 122.723 128.244 166.307 1.00 63.40  ? 5   TYR A CD2   1 
ATOM   34   C  CE1   . TYR A 1 5   ? 123.431 125.594 166.511 1.00 58.60  ? 5   TYR A CE1   1 
ATOM   35   C  CE2   . TYR A 1 5   ? 124.031 127.866 166.100 1.00 63.02  ? 5   TYR A CE2   1 
ATOM   36   C  CZ    . TYR A 1 5   ? 124.379 126.541 166.204 1.00 65.09  ? 5   TYR A CZ    1 
ATOM   37   O  OH    . TYR A 1 5   ? 125.684 126.161 165.998 1.00 75.49  ? 5   TYR A OH    1 
ATOM   38   N  N     . SER A 1 6   ? 121.469 127.281 169.962 1.00 65.88  ? 6   SER A N     1 
ATOM   39   C  CA    . SER A 1 6   ? 122.320 127.812 171.017 1.00 64.28  ? 6   SER A CA    1 
ATOM   40   C  C     . SER A 1 6   ? 123.754 127.383 170.758 1.00 64.35  ? 6   SER A C     1 
ATOM   41   O  O     . SER A 1 6   ? 124.020 126.197 170.544 1.00 63.26  ? 6   SER A O     1 
ATOM   42   C  CB    . SER A 1 6   ? 121.861 127.329 172.392 1.00 63.28  ? 6   SER A CB    1 
ATOM   43   O  OG    . SER A 1 6   ? 121.825 125.916 172.435 1.00 64.39  ? 6   SER A OG    1 
ATOM   44   N  N     . ILE A 1 7   ? 124.674 128.348 170.785 1.00 63.08  ? 7   ILE A N     1 
ATOM   45   C  CA    . ILE A 1 7   ? 126.067 128.062 170.455 1.00 62.09  ? 7   ILE A CA    1 
ATOM   46   C  C     . ILE A 1 7   ? 126.711 127.191 171.526 1.00 68.42  ? 7   ILE A C     1 
ATOM   47   O  O     . ILE A 1 7   ? 127.460 126.257 171.217 1.00 73.46  ? 7   ILE A O     1 
ATOM   48   C  CB    . ILE A 1 7   ? 126.842 129.374 170.246 1.00 52.16  ? 7   ILE A CB    1 
ATOM   49   C  CG1   . ILE A 1 7   ? 126.323 130.104 169.009 1.00 52.88  ? 7   ILE A CG1   1 
ATOM   50   C  CG2   . ILE A 1 7   ? 128.328 129.101 170.109 1.00 54.98  ? 7   ILE A CG2   1 
ATOM   51   C  CD1   . ILE A 1 7   ? 125.404 131.258 169.321 1.00 58.77  ? 7   ILE A CD1   1 
ATOM   52   N  N     . GLU A 1 8   ? 126.435 127.481 172.800 1.00 66.34  ? 8   GLU A N     1 
ATOM   53   C  CA    . GLU A 1 8   ? 127.090 126.752 173.882 1.00 64.82  ? 8   GLU A CA    1 
ATOM   54   C  C     . GLU A 1 8   ? 126.694 125.281 173.889 1.00 69.04  ? 8   GLU A C     1 
ATOM   55   O  O     . GLU A 1 8   ? 127.549 124.401 174.043 1.00 75.95  ? 8   GLU A O     1 
ATOM   56   C  CB    . GLU A 1 8   ? 126.758 127.402 175.224 1.00 65.16  ? 8   GLU A CB    1 
ATOM   57   C  CG    . GLU A 1 8   ? 127.422 128.750 175.439 1.00 76.62  ? 8   GLU A CG    1 
ATOM   58   C  CD    . GLU A 1 8   ? 128.907 128.729 175.141 1.00 81.92  ? 8   GLU A CD    1 
ATOM   59   O  OE1   . GLU A 1 8   ? 129.634 127.946 175.787 1.00 84.28  ? 8   GLU A OE1   1 
ATOM   60   O  OE2   . GLU A 1 8   ? 129.352 129.499 174.264 1.00 79.75  ? 8   GLU A OE2   1 
ATOM   61   N  N     . ALA A 1 9   ? 125.402 124.990 173.722 1.00 65.62  ? 9   ALA A N     1 
ATOM   62   C  CA    . ALA A 1 9   ? 124.955 123.602 173.755 1.00 66.77  ? 9   ALA A CA    1 
ATOM   63   C  C     . ALA A 1 9   ? 125.456 122.829 172.543 1.00 70.41  ? 9   ALA A C     1 
ATOM   64   O  O     . ALA A 1 9   ? 125.756 121.635 172.644 1.00 78.39  ? 9   ALA A O     1 
ATOM   65   C  CB    . ALA A 1 9   ? 123.432 123.538 173.843 1.00 63.54  ? 9   ALA A CB    1 
ATOM   66   N  N     . THR A 1 10  ? 125.543 123.488 171.387 1.00 66.68  ? 10  THR A N     1 
ATOM   67   C  CA    . THR A 1 10  ? 126.116 122.840 170.212 1.00 69.76  ? 10  THR A CA    1 
ATOM   68   C  C     . THR A 1 10  ? 127.597 122.551 170.416 1.00 70.55  ? 10  THR A C     1 
ATOM   69   O  O     . THR A 1 10  ? 128.086 121.476 170.048 1.00 71.57  ? 10  THR A O     1 
ATOM   70   C  CB    . THR A 1 10  ? 125.898 123.712 168.975 1.00 67.14  ? 10  THR A CB    1 
ATOM   71   O  OG1   . THR A 1 10  ? 124.578 123.490 168.466 1.00 70.44  ? 10  THR A OG1   1 
ATOM   72   C  CG2   . THR A 1 10  ? 126.911 123.381 167.892 1.00 62.51  ? 10  THR A CG2   1 
ATOM   73   N  N     . ARG A 1 11  ? 128.325 123.495 171.016 1.00 69.03  ? 11  ARG A N     1 
ATOM   74   C  CA    . ARG A 1 11  ? 129.742 123.279 171.286 1.00 70.18  ? 11  ARG A CA    1 
ATOM   75   C  C     . ARG A 1 11  ? 129.947 122.140 172.277 1.00 73.17  ? 11  ARG A C     1 
ATOM   76   O  O     . ARG A 1 11  ? 130.891 121.354 172.144 1.00 77.58  ? 11  ARG A O     1 
ATOM   77   C  CB    . ARG A 1 11  ? 130.375 124.568 171.805 1.00 68.63  ? 11  ARG A CB    1 
ATOM   78   C  CG    . ARG A 1 11  ? 131.855 124.455 172.117 1.00 73.33  ? 11  ARG A CG    1 
ATOM   79   C  CD    . ARG A 1 11  ? 132.410 125.770 172.635 1.00 81.33  ? 11  ARG A CD    1 
ATOM   80   N  NE    . ARG A 1 11  ? 132.444 125.811 174.092 1.00 94.19  ? 11  ARG A NE    1 
ATOM   81   C  CZ    . ARG A 1 11  ? 133.503 126.167 174.805 1.00 101.96 ? 11  ARG A CZ    1 
ATOM   82   N  NH1   . ARG A 1 11  ? 134.639 126.519 174.227 1.00 103.64 ? 11  ARG A NH1   1 
ATOM   83   N  NH2   . ARG A 1 11  ? 133.420 126.170 176.133 1.00 95.19  ? 11  ARG A NH2   1 
ATOM   84   N  N     . ASN A 1 12  ? 129.069 122.034 173.278 1.00 71.51  ? 12  ASN A N     1 
ATOM   85   C  CA    . ASN A 1 12  ? 129.197 120.973 174.271 1.00 70.46  ? 12  ASN A CA    1 
ATOM   86   C  C     . ASN A 1 12  ? 128.912 119.591 173.697 1.00 71.08  ? 12  ASN A C     1 
ATOM   87   O  O     . ASN A 1 12  ? 129.248 118.589 174.338 1.00 75.92  ? 12  ASN A O     1 
ATOM   88   C  CB    . ASN A 1 12  ? 128.262 121.240 175.451 1.00 71.78  ? 12  ASN A CB    1 
ATOM   89   C  CG    . ASN A 1 12  ? 128.715 122.409 176.300 1.00 81.43  ? 12  ASN A CG    1 
ATOM   90   O  OD1   . ASN A 1 12  ? 129.829 122.907 176.148 1.00 78.94  ? 12  ASN A OD1   1 
ATOM   91   N  ND2   . ASN A 1 12  ? 127.850 122.853 177.204 1.00 84.55  ? 12  ASN A ND2   1 
ATOM   92   N  N     . LEU A 1 13  ? 128.301 119.511 172.518 1.00 73.07  ? 13  LEU A N     1 
ATOM   93   C  CA    . LEU A 1 13  ? 127.979 118.223 171.922 1.00 74.35  ? 13  LEU A CA    1 
ATOM   94   C  C     . LEU A 1 13  ? 129.245 117.485 171.498 1.00 77.24  ? 13  LEU A C     1 
ATOM   95   O  O     . LEU A 1 13  ? 130.226 118.088 171.057 1.00 81.14  ? 13  LEU A O     1 
ATOM   96   C  CB    . LEU A 1 13  ? 127.065 118.406 170.713 1.00 68.42  ? 13  LEU A CB    1 
ATOM   97   C  CG    . LEU A 1 13  ? 125.589 118.692 170.988 1.00 69.67  ? 13  LEU A CG    1 
ATOM   98   C  CD1   . LEU A 1 13  ? 124.786 118.597 169.704 1.00 69.02  ? 13  LEU A CD1   1 
ATOM   99   C  CD2   . LEU A 1 13  ? 125.043 117.743 172.039 1.00 74.96  ? 13  LEU A CD2   1 
ATOM   100  N  N     . ALA A 1 14  ? 129.213 116.163 171.636 1.00 73.85  ? 14  ALA A N     1 
ATOM   101  C  CA    . ALA A 1 14  ? 130.320 115.339 171.184 1.00 75.32  ? 14  ALA A CA    1 
ATOM   102  C  C     . ALA A 1 14  ? 130.349 115.284 169.659 1.00 79.42  ? 14  ALA A C     1 
ATOM   103  O  O     . ALA A 1 14  ? 129.384 115.637 168.976 1.00 83.12  ? 14  ALA A O     1 
ATOM   104  C  CB    . ALA A 1 14  ? 130.215 113.932 171.769 1.00 77.76  ? 14  ALA A CB    1 
ATOM   105  N  N     . THR A 1 15  ? 131.486 114.837 169.122 1.00 77.61  ? 15  THR A N     1 
ATOM   106  C  CA    . THR A 1 15  ? 131.652 114.790 167.672 1.00 80.17  ? 15  THR A CA    1 
ATOM   107  C  C     . THR A 1 15  ? 130.658 113.829 167.030 1.00 78.63  ? 15  THR A C     1 
ATOM   108  O  O     . THR A 1 15  ? 130.081 114.130 165.978 1.00 75.89  ? 15  THR A O     1 
ATOM   109  C  CB    . THR A 1 15  ? 133.089 114.399 167.323 1.00 82.82  ? 15  THR A CB    1 
ATOM   110  O  OG1   . THR A 1 15  ? 133.936 115.548 167.439 1.00 86.76  ? 15  THR A OG1   1 
ATOM   111  C  CG2   . THR A 1 15  ? 133.177 113.862 165.904 1.00 76.94  ? 15  THR A CG2   1 
ATOM   112  N  N     . THR A 1 16  ? 130.428 112.675 167.655 1.00 76.89  ? 16  THR A N     1 
ATOM   113  C  CA    . THR A 1 16  ? 129.502 111.692 167.108 1.00 72.12  ? 16  THR A CA    1 
ATOM   114  C  C     . THR A 1 16  ? 128.045 112.007 167.420 1.00 72.91  ? 16  THR A C     1 
ATOM   115  O  O     . THR A 1 16  ? 127.160 111.292 166.938 1.00 76.49  ? 16  THR A O     1 
ATOM   116  C  CB    . THR A 1 16  ? 129.839 110.296 167.634 1.00 74.38  ? 16  THR A CB    1 
ATOM   117  O  OG1   . THR A 1 16  ? 128.768 109.397 167.322 1.00 74.10  ? 16  THR A OG1   1 
ATOM   118  C  CG2   . THR A 1 16  ? 130.039 110.330 169.139 1.00 79.24  ? 16  THR A CG2   1 
ATOM   119  N  N     . GLU A 1 17  ? 127.775 113.043 168.210 1.00 72.10  ? 17  GLU A N     1 
ATOM   120  C  CA    . GLU A 1 17  ? 126.418 113.428 168.569 1.00 72.21  ? 17  GLU A CA    1 
ATOM   121  C  C     . GLU A 1 17  ? 125.959 114.696 167.860 1.00 72.61  ? 17  GLU A C     1 
ATOM   122  O  O     . GLU A 1 17  ? 124.923 115.257 168.227 1.00 72.46  ? 17  GLU A O     1 
ATOM   123  C  CB    . GLU A 1 17  ? 126.310 113.611 170.084 1.00 78.36  ? 17  GLU A CB    1 
ATOM   124  C  CG    . GLU A 1 17  ? 125.352 112.651 170.766 1.00 90.07  ? 17  GLU A CG    1 
ATOM   125  C  CD    . GLU A 1 17  ? 123.930 113.177 170.809 1.00 104.96 ? 17  GLU A CD    1 
ATOM   126  O  OE1   . GLU A 1 17  ? 123.746 114.405 170.676 1.00 107.16 ? 17  GLU A OE1   1 
ATOM   127  O  OE2   . GLU A 1 17  ? 122.997 112.364 170.978 1.00 101.65 ? 17  GLU A OE2   1 
ATOM   128  N  N     . ARG A 1 18  ? 126.700 115.160 166.861 1.00 67.03  ? 18  ARG A N     1 
ATOM   129  C  CA    . ARG A 1 18  ? 126.393 116.422 166.209 1.00 57.91  ? 18  ARG A CA    1 
ATOM   130  C  C     . ARG A 1 18  ? 125.386 116.228 165.081 1.00 55.92  ? 18  ARG A C     1 
ATOM   131  O  O     . ARG A 1 18  ? 125.192 115.126 164.564 1.00 59.71  ? 18  ARG A O     1 
ATOM   132  C  CB    . ARG A 1 18  ? 127.668 117.073 165.676 1.00 55.20  ? 18  ARG A CB    1 
ATOM   133  C  CG    . ARG A 1 18  ? 128.293 118.047 166.655 1.00 63.77  ? 18  ARG A CG    1 
ATOM   134  C  CD    . ARG A 1 18  ? 129.743 118.326 166.323 1.00 71.07  ? 18  ARG A CD    1 
ATOM   135  N  NE    . ARG A 1 18  ? 130.374 119.148 167.347 1.00 77.48  ? 18  ARG A NE    1 
ATOM   136  C  CZ    . ARG A 1 18  ? 131.683 119.311 167.474 1.00 81.81  ? 18  ARG A CZ    1 
ATOM   137  N  NH1   . ARG A 1 18  ? 132.535 118.725 166.649 1.00 79.23  ? 18  ARG A NH1   1 
ATOM   138  N  NH2   . ARG A 1 18  ? 132.149 120.080 168.454 1.00 80.59  ? 18  ARG A NH2   1 
ATOM   139  N  N     . CYS A 1 19  ? 124.740 117.334 164.704 1.00 51.83  ? 19  CYS A N     1 
ATOM   140  C  CA    . CYS A 1 19  ? 123.681 117.282 163.701 1.00 51.04  ? 19  CYS A CA    1 
ATOM   141  C  C     . CYS A 1 19  ? 124.222 116.914 162.325 1.00 48.94  ? 19  CYS A C     1 
ATOM   142  O  O     . CYS A 1 19  ? 123.586 116.154 161.587 1.00 51.67  ? 19  CYS A O     1 
ATOM   143  C  CB    . CYS A 1 19  ? 122.951 118.622 163.644 1.00 48.63  ? 19  CYS A CB    1 
ATOM   144  S  SG    . CYS A 1 19  ? 122.561 119.327 165.258 1.00 66.80  ? 19  CYS A SG    1 
ATOM   145  N  N     . ILE A 1 20  ? 125.383 117.445 161.956 1.00 46.67  ? 20  ILE A N     1 
ATOM   146  C  CA    . ILE A 1 20  ? 125.946 117.268 160.623 1.00 40.74  ? 20  ILE A CA    1 
ATOM   147  C  C     . ILE A 1 20  ? 127.240 116.477 160.739 1.00 51.62  ? 20  ILE A C     1 
ATOM   148  O  O     . ILE A 1 20  ? 128.136 116.850 161.504 1.00 64.88  ? 20  ILE A O     1 
ATOM   149  C  CB    . ILE A 1 20  ? 126.195 118.620 159.937 1.00 40.63  ? 20  ILE A CB    1 
ATOM   150  C  CG1   . ILE A 1 20  ? 124.884 119.396 159.808 1.00 45.24  ? 20  ILE A CG1   1 
ATOM   151  C  CG2   . ILE A 1 20  ? 126.847 118.414 158.586 1.00 45.49  ? 20  ILE A CG2   1 
ATOM   152  C  CD1   . ILE A 1 20  ? 124.062 119.003 158.613 1.00 47.35  ? 20  ILE A CD1   1 
ATOM   153  N  N     . GLN A 1 21  ? 127.340 115.392 159.978 1.00 53.02  ? 21  GLN A N     1 
ATOM   154  C  CA    . GLN A 1 21  ? 128.529 114.554 159.954 1.00 50.70  ? 21  GLN A CA    1 
ATOM   155  C  C     . GLN A 1 21  ? 129.336 114.855 158.700 1.00 55.25  ? 21  GLN A C     1 
ATOM   156  O  O     . GLN A 1 21  ? 128.786 114.894 157.595 1.00 59.98  ? 21  GLN A O     1 
ATOM   157  C  CB    . GLN A 1 21  ? 128.150 113.074 159.998 1.00 47.93  ? 21  GLN A CB    1 
ATOM   158  C  CG    . GLN A 1 21  ? 127.289 112.695 161.185 1.00 55.11  ? 21  GLN A CG    1 
ATOM   159  C  CD    . GLN A 1 21  ? 127.899 113.121 162.501 1.00 57.73  ? 21  GLN A CD    1 
ATOM   160  O  OE1   . GLN A 1 21  ? 127.523 114.144 163.069 1.00 58.47  ? 21  GLN A OE1   1 
ATOM   161  N  NE2   . GLN A 1 21  ? 128.849 112.338 162.994 1.00 61.43  ? 21  GLN A NE2   1 
ATOM   162  N  N     . ASP A 1 22  ? 130.635 115.076 158.877 1.00 56.93  ? 22  ASP A N     1 
ATOM   163  C  CA    . ASP A 1 22  ? 131.544 115.334 157.766 1.00 56.63  ? 22  ASP A CA    1 
ATOM   164  C  C     . ASP A 1 22  ? 132.057 113.994 157.252 1.00 52.71  ? 22  ASP A C     1 
ATOM   165  O  O     . ASP A 1 22  ? 132.876 113.343 157.908 1.00 55.00  ? 22  ASP A O     1 
ATOM   166  C  CB    . ASP A 1 22  ? 132.693 116.234 158.214 1.00 62.52  ? 22  ASP A CB    1 
ATOM   167  C  CG    . ASP A 1 22  ? 133.698 116.500 157.110 1.00 68.72  ? 22  ASP A CG    1 
ATOM   168  O  OD1   . ASP A 1 22  ? 133.381 116.252 155.928 1.00 69.97  ? 22  ASP A OD1   1 
ATOM   169  O  OD2   . ASP A 1 22  ? 134.816 116.959 157.426 1.00 70.86  ? 22  ASP A OD2   1 
ATOM   170  N  N     . ILE A 1 23  ? 131.575 113.582 156.081 1.00 52.81  ? 23  ILE A N     1 
ATOM   171  C  CA    . ILE A 1 23  ? 131.983 112.311 155.495 1.00 58.00  ? 23  ILE A CA    1 
ATOM   172  C  C     . ILE A 1 23  ? 132.658 112.558 154.154 1.00 61.39  ? 23  ILE A C     1 
ATOM   173  O  O     . ILE A 1 23  ? 132.563 111.735 153.238 1.00 63.80  ? 23  ILE A O     1 
ATOM   174  C  CB    . ILE A 1 23  ? 130.794 111.344 155.352 1.00 54.42  ? 23  ILE A CB    1 
ATOM   175  C  CG1   . ILE A 1 23  ? 129.682 111.964 154.510 1.00 51.71  ? 23  ILE A CG1   1 
ATOM   176  C  CG2   . ILE A 1 23  ? 130.262 110.948 156.717 1.00 58.13  ? 23  ILE A CG2   1 
ATOM   177  C  CD1   . ILE A 1 23  ? 128.544 111.013 154.258 1.00 54.56  ? 23  ILE A CD1   1 
ATOM   178  N  N     . ARG A 1 24  ? 133.338 113.701 154.027 1.00 58.21  ? 24  ARG A N     1 
ATOM   179  C  CA    . ARG A 1 24  ? 134.112 113.963 152.818 1.00 60.77  ? 24  ARG A CA    1 
ATOM   180  C  C     . ARG A 1 24  ? 135.219 112.932 152.643 1.00 62.54  ? 24  ARG A C     1 
ATOM   181  O  O     . ARG A 1 24  ? 135.471 112.464 151.526 1.00 61.65  ? 24  ARG A O     1 
ATOM   182  C  CB    . ARG A 1 24  ? 134.698 115.374 152.863 1.00 59.78  ? 24  ARG A CB    1 
ATOM   183  C  CG    . ARG A 1 24  ? 134.696 116.104 151.524 1.00 69.90  ? 24  ARG A CG    1 
ATOM   184  C  CD    . ARG A 1 24  ? 135.714 115.520 150.547 1.00 69.00  ? 24  ARG A CD    1 
ATOM   185  N  NE    . ARG A 1 24  ? 135.999 116.429 149.443 1.00 61.09  ? 24  ARG A NE    1 
ATOM   186  C  CZ    . ARG A 1 24  ? 137.109 116.405 148.718 1.00 51.93  ? 24  ARG A CZ    1 
ATOM   187  N  NH1   . ARG A 1 24  ? 138.058 115.511 148.938 1.00 46.85  ? 24  ARG A NH1   1 
ATOM   188  N  NH2   . ARG A 1 24  ? 137.270 117.301 147.749 1.00 46.68  ? 24  ARG A NH2   1 
ATOM   189  N  N     . ASN A 1 25  ? 135.887 112.560 153.734 1.00 61.01  ? 25  ASN A N     1 
ATOM   190  C  CA    . ASN A 1 25  ? 136.982 111.602 153.664 1.00 58.34  ? 25  ASN A CA    1 
ATOM   191  C  C     . ASN A 1 25  ? 136.515 110.153 153.699 1.00 59.65  ? 25  ASN A C     1 
ATOM   192  O  O     . ASN A 1 25  ? 137.343 109.253 153.525 1.00 66.28  ? 25  ASN A O     1 
ATOM   193  C  CB    . ASN A 1 25  ? 137.967 111.845 154.809 1.00 58.63  ? 25  ASN A CB    1 
ATOM   194  C  CG    . ASN A 1 25  ? 139.014 112.885 154.466 1.00 66.62  ? 25  ASN A CG    1 
ATOM   195  O  OD1   . ASN A 1 25  ? 139.555 112.897 153.362 1.00 69.49  ? 25  ASN A OD1   1 
ATOM   196  N  ND2   . ASN A 1 25  ? 139.306 113.765 155.415 1.00 74.22  ? 25  ASN A ND2   1 
ATOM   197  N  N     . ALA A 1 26  ? 135.228 109.903 153.923 1.00 56.17  ? 26  ALA A N     1 
ATOM   198  C  CA    . ALA A 1 26  ? 134.668 108.552 153.942 1.00 56.62  ? 26  ALA A CA    1 
ATOM   199  C  C     . ALA A 1 26  ? 133.403 108.522 153.094 1.00 61.27  ? 26  ALA A C     1 
ATOM   200  O  O     . ALA A 1 26  ? 132.291 108.399 153.620 1.00 67.28  ? 26  ALA A O     1 
ATOM   201  C  CB    . ALA A 1 26  ? 134.382 108.097 155.373 1.00 54.33  ? 26  ALA A CB    1 
ATOM   202  N  N     . PRO A 1 27  ? 133.538 108.631 151.774 1.00 62.62  ? 27  PRO A N     1 
ATOM   203  C  CA    . PRO A 1 27  ? 132.351 108.717 150.917 1.00 63.72  ? 27  PRO A CA    1 
ATOM   204  C  C     . PRO A 1 27  ? 131.528 107.441 150.949 1.00 67.77  ? 27  PRO A C     1 
ATOM   205  O  O     . PRO A 1 27  ? 132.039 106.346 151.195 1.00 66.41  ? 27  PRO A O     1 
ATOM   206  C  CB    . PRO A 1 27  ? 132.934 108.958 149.518 1.00 58.50  ? 27  PRO A CB    1 
ATOM   207  C  CG    . PRO A 1 27  ? 134.362 109.341 149.735 1.00 58.79  ? 27  PRO A CG    1 
ATOM   208  C  CD    . PRO A 1 27  ? 134.783 108.660 150.991 1.00 61.97  ? 27  PRO A CD    1 
ATOM   209  N  N     . VAL A 1 28  ? 130.229 107.600 150.703 1.00 72.76  ? 28  VAL A N     1 
ATOM   210  C  CA    . VAL A 1 28  ? 129.327 106.465 150.544 1.00 73.42  ? 28  VAL A CA    1 
ATOM   211  C  C     . VAL A 1 28  ? 129.607 105.858 149.174 1.00 81.07  ? 28  VAL A C     1 
ATOM   212  O  O     . VAL A 1 28  ? 130.319 106.455 148.360 1.00 83.92  ? 28  VAL A O     1 
ATOM   213  C  CB    . VAL A 1 28  ? 127.857 106.892 150.701 1.00 70.47  ? 28  VAL A CB    1 
ATOM   214  C  CG1   . VAL A 1 28  ? 126.971 105.689 150.987 1.00 69.93  ? 28  VAL A CG1   1 
ATOM   215  C  CG2   . VAL A 1 28  ? 127.728 107.917 151.812 1.00 70.77  ? 28  VAL A CG2   1 
ATOM   216  N  N     . ARG A 1 29  ? 129.064 104.667 148.913 1.00 80.47  ? 29  ARG A N     1 
ATOM   217  C  CA    . ARG A 1 29  ? 129.464 103.903 147.735 1.00 86.87  ? 29  ARG A CA    1 
ATOM   218  C  C     . ARG A 1 29  ? 129.167 104.658 146.443 1.00 85.92  ? 29  ARG A C     1 
ATOM   219  O  O     . ARG A 1 29  ? 130.082 105.021 145.696 1.00 93.00  ? 29  ARG A O     1 
ATOM   220  C  CB    . ARG A 1 29  ? 128.767 102.542 147.735 1.00 93.97  ? 29  ARG A CB    1 
ATOM   221  C  CG    . ARG A 1 29  ? 129.511 101.468 148.508 1.00 105.99 ? 29  ARG A CG    1 
ATOM   222  C  CD    . ARG A 1 29  ? 130.978 101.398 148.097 1.00 100.92 ? 29  ARG A CD    1 
ATOM   223  N  NE    . ARG A 1 29  ? 131.168 101.312 146.652 1.00 103.86 ? 29  ARG A NE    1 
ATOM   224  C  CZ    . ARG A 1 29  ? 130.742 100.316 145.885 1.00 108.24 ? 29  ARG A CZ    1 
ATOM   225  N  NH1   . ARG A 1 29  ? 130.121 99.264  146.393 1.00 107.03 ? 29  ARG A NH1   1 
ATOM   226  N  NH2   . ARG A 1 29  ? 130.956 100.372 144.574 1.00 111.92 ? 29  ARG A NH2   1 
ATOM   227  N  N     . ASN A 1 30  ? 127.890 104.909 146.164 1.00 79.56  ? 30  ASN A N     1 
ATOM   228  C  CA    . ASN A 1 30  ? 127.474 105.488 144.892 1.00 80.00  ? 30  ASN A CA    1 
ATOM   229  C  C     . ASN A 1 30  ? 126.880 106.883 145.056 1.00 78.18  ? 30  ASN A C     1 
ATOM   230  O  O     . ASN A 1 30  ? 126.007 107.285 144.284 1.00 77.79  ? 30  ASN A O     1 
ATOM   231  C  CB    . ASN A 1 30  ? 126.480 104.565 144.191 1.00 87.07  ? 30  ASN A CB    1 
ATOM   232  C  CG    . ASN A 1 30  ? 127.156 103.396 143.503 1.00 96.43  ? 30  ASN A CG    1 
ATOM   233  O  OD1   . ASN A 1 30  ? 128.251 103.531 142.959 1.00 101.59 ? 30  ASN A OD1   1 
ATOM   234  N  ND2   . ASN A 1 30  ? 126.505 102.240 143.524 1.00 101.92 ? 30  ASN A ND2   1 
ATOM   235  N  N     . ARG A 1 31  ? 127.343 107.634 146.051 1.00 77.20  ? 31  ARG A N     1 
ATOM   236  C  CA    . ARG A 1 31  ? 126.839 108.971 146.315 1.00 68.41  ? 31  ARG A CA    1 
ATOM   237  C  C     . ARG A 1 31  ? 128.001 109.927 146.536 1.00 70.10  ? 31  ARG A C     1 
ATOM   238  O  O     . ARG A 1 31  ? 129.120 109.520 146.857 1.00 75.77  ? 31  ARG A O     1 
ATOM   239  C  CB    . ARG A 1 31  ? 125.909 108.993 147.534 1.00 59.38  ? 31  ARG A CB    1 
ATOM   240  C  CG    . ARG A 1 31  ? 124.751 108.024 147.438 1.00 57.11  ? 31  ARG A CG    1 
ATOM   241  C  CD    . ARG A 1 31  ? 123.788 108.198 148.591 1.00 50.91  ? 31  ARG A CD    1 
ATOM   242  N  NE    . ARG A 1 31  ? 122.954 107.016 148.764 1.00 42.22  ? 31  ARG A NE    1 
ATOM   243  C  CZ    . ARG A 1 31  ? 122.511 106.580 149.934 1.00 48.77  ? 31  ARG A CZ    1 
ATOM   244  N  NH1   . ARG A 1 31  ? 122.788 107.219 151.058 1.00 55.44  ? 31  ARG A NH1   1 
ATOM   245  N  NH2   . ARG A 1 31  ? 121.773 105.475 149.976 1.00 52.91  ? 31  ARG A NH2   1 
ATOM   246  N  N     . SER A 1 32  ? 127.718 111.215 146.356 1.00 63.07  ? 32  SER A N     1 
ATOM   247  C  CA    . SER A 1 32  ? 128.693 112.278 146.555 1.00 58.98  ? 32  SER A CA    1 
ATOM   248  C  C     . SER A 1 32  ? 128.308 113.188 147.716 1.00 56.62  ? 32  SER A C     1 
ATOM   249  O  O     . SER A 1 32  ? 128.589 114.388 147.692 1.00 56.90  ? 32  SER A O     1 
ATOM   250  C  CB    . SER A 1 32  ? 128.862 113.092 145.275 1.00 58.55  ? 32  SER A CB    1 
ATOM   251  O  OG    . SER A 1 32  ? 127.703 113.863 145.013 1.00 56.05  ? 32  SER A OG    1 
ATOM   252  N  N     . THR A 1 33  ? 127.662 112.631 148.736 1.00 53.53  ? 33  THR A N     1 
ATOM   253  C  CA    . THR A 1 33  ? 127.210 113.407 149.887 1.00 47.14  ? 33  THR A CA    1 
ATOM   254  C  C     . THR A 1 33  ? 128.423 113.837 150.698 1.00 49.01  ? 33  THR A C     1 
ATOM   255  O  O     . THR A 1 33  ? 129.012 113.039 151.428 1.00 59.62  ? 33  THR A O     1 
ATOM   256  C  CB    . THR A 1 33  ? 126.250 112.586 150.740 1.00 45.24  ? 33  THR A CB    1 
ATOM   257  O  OG1   . THR A 1 33  ? 126.998 111.702 151.578 1.00 56.81  ? 33  THR A OG1   1 
ATOM   258  C  CG2   . THR A 1 33  ? 125.332 111.762 149.865 1.00 48.57  ? 33  THR A CG2   1 
ATOM   259  N  N     . GLN A 1 34  ? 128.809 115.106 150.567 1.00 44.20  ? 34  GLN A N     1 
ATOM   260  C  CA    . GLN A 1 34  ? 129.940 115.611 151.336 1.00 48.85  ? 34  GLN A CA    1 
ATOM   261  C  C     . GLN A 1 34  ? 129.602 115.701 152.819 1.00 55.56  ? 34  GLN A C     1 
ATOM   262  O  O     . GLN A 1 34  ? 130.362 115.224 153.668 1.00 61.12  ? 34  GLN A O     1 
ATOM   263  C  CB    . GLN A 1 34  ? 130.375 116.972 150.796 1.00 47.70  ? 34  GLN A CB    1 
ATOM   264  C  CG    . GLN A 1 34  ? 130.895 116.926 149.375 1.00 49.01  ? 34  GLN A CG    1 
ATOM   265  C  CD    . GLN A 1 34  ? 131.838 118.064 149.067 1.00 54.19  ? 34  GLN A CD    1 
ATOM   266  O  OE1   . GLN A 1 34  ? 132.309 118.757 149.967 1.00 54.44  ? 34  GLN A OE1   1 
ATOM   267  N  NE2   . GLN A 1 34  ? 132.124 118.262 147.787 1.00 59.41  ? 34  GLN A NE2   1 
ATOM   268  N  N     . PHE A 1 35  ? 128.461 116.300 153.149 1.00 52.77  ? 35  PHE A N     1 
ATOM   269  C  CA    . PHE A 1 35  ? 128.001 116.429 154.525 1.00 46.77  ? 35  PHE A CA    1 
ATOM   270  C  C     . PHE A 1 35  ? 126.678 115.695 154.671 1.00 49.42  ? 35  PHE A C     1 
ATOM   271  O  O     . PHE A 1 35  ? 125.769 115.881 153.857 1.00 54.09  ? 35  PHE A O     1 
ATOM   272  C  CB    . PHE A 1 35  ? 127.840 117.895 154.923 1.00 41.88  ? 35  PHE A CB    1 
ATOM   273  C  CG    . PHE A 1 35  ? 129.104 118.692 154.820 1.00 43.54  ? 35  PHE A CG    1 
ATOM   274  C  CD1   . PHE A 1 35  ? 129.962 118.792 155.896 1.00 47.83  ? 35  PHE A CD1   1 
ATOM   275  C  CD2   . PHE A 1 35  ? 129.431 119.348 153.648 1.00 49.31  ? 35  PHE A CD2   1 
ATOM   276  C  CE1   . PHE A 1 35  ? 131.124 119.525 155.801 1.00 55.27  ? 35  PHE A CE1   1 
ATOM   277  C  CE2   . PHE A 1 35  ? 130.592 120.083 153.550 1.00 49.85  ? 35  PHE A CE2   1 
ATOM   278  C  CZ    . PHE A 1 35  ? 131.440 120.172 154.627 1.00 55.19  ? 35  PHE A CZ    1 
ATOM   279  N  N     . GLN A 1 36  ? 126.570 114.870 155.707 1.00 49.29  ? 36  GLN A N     1 
ATOM   280  C  CA    . GLN A 1 36  ? 125.402 114.027 155.921 1.00 49.89  ? 36  GLN A CA    1 
ATOM   281  C  C     . GLN A 1 36  ? 124.612 114.562 157.107 1.00 53.17  ? 36  GLN A C     1 
ATOM   282  O  O     . GLN A 1 36  ? 125.155 114.701 158.207 1.00 64.16  ? 36  GLN A O     1 
ATOM   283  C  CB    . GLN A 1 36  ? 125.825 112.576 156.151 1.00 52.64  ? 36  GLN A CB    1 
ATOM   284  C  CG    . GLN A 1 36  ? 124.954 111.792 157.113 1.00 53.72  ? 36  GLN A CG    1 
ATOM   285  C  CD    . GLN A 1 36  ? 125.192 110.299 157.016 1.00 68.85  ? 36  GLN A CD    1 
ATOM   286  O  OE1   . GLN A 1 36  ? 125.661 109.799 155.994 1.00 71.05  ? 36  GLN A OE1   1 
ATOM   287  N  NE2   . GLN A 1 36  ? 124.876 109.579 158.084 1.00 77.30  ? 36  GLN A NE2   1 
ATOM   288  N  N     . LEU A 1 37  ? 123.344 114.884 156.877 1.00 46.14  ? 37  LEU A N     1 
ATOM   289  C  CA    . LEU A 1 37  ? 122.467 115.267 157.972 1.00 42.18  ? 37  LEU A CA    1 
ATOM   290  C  C     . LEU A 1 37  ? 122.187 114.050 158.842 1.00 45.74  ? 37  LEU A C     1 
ATOM   291  O  O     . LEU A 1 37  ? 121.817 112.988 158.335 1.00 56.83  ? 37  LEU A O     1 
ATOM   292  C  CB    . LEU A 1 37  ? 121.160 115.843 157.431 1.00 42.13  ? 37  LEU A CB    1 
ATOM   293  C  CG    . LEU A 1 37  ? 121.053 117.361 157.296 1.00 32.95  ? 37  LEU A CG    1 
ATOM   294  C  CD1   . LEU A 1 37  ? 121.678 117.820 156.000 1.00 34.09  ? 37  LEU A CD1   1 
ATOM   295  C  CD2   . LEU A 1 37  ? 119.606 117.803 157.370 1.00 32.69  ? 37  LEU A CD2   1 
ATOM   296  N  N     . ALA A 1 38  ? 122.367 114.194 160.150 1.00 39.46  ? 38  ALA A N     1 
ATOM   297  C  CA    . ALA A 1 38  ? 122.117 113.107 161.092 1.00 49.56  ? 38  ALA A CA    1 
ATOM   298  C  C     . ALA A 1 38  ? 120.703 113.277 161.632 1.00 52.14  ? 38  ALA A C     1 
ATOM   299  O  O     . ALA A 1 38  ? 120.478 114.022 162.586 1.00 54.94  ? 38  ALA A O     1 
ATOM   300  C  CB    . ALA A 1 38  ? 123.150 113.101 162.212 1.00 53.94  ? 38  ALA A CB    1 
ATOM   301  N  N     . GLN A 1 39  ? 119.756 112.557 161.030 1.00 52.23  ? 39  GLN A N     1 
ATOM   302  C  CA    . GLN A 1 39  ? 118.345 112.728 161.365 1.00 46.78  ? 39  GLN A CA    1 
ATOM   303  C  C     . GLN A 1 39  ? 118.086 112.460 162.843 1.00 52.91  ? 39  GLN A C     1 
ATOM   304  O  O     . GLN A 1 39  ? 117.410 113.244 163.520 1.00 59.63  ? 39  GLN A O     1 
ATOM   305  C  CB    . GLN A 1 39  ? 117.507 111.800 160.490 1.00 43.95  ? 39  GLN A CB    1 
ATOM   306  C  CG    . GLN A 1 39  ? 116.196 111.360 161.094 1.00 54.13  ? 39  GLN A CG    1 
ATOM   307  C  CD    . GLN A 1 39  ? 115.627 110.154 160.382 1.00 60.70  ? 39  GLN A CD    1 
ATOM   308  O  OE1   . GLN A 1 39  ? 115.226 109.177 161.013 1.00 61.80  ? 39  GLN A OE1   1 
ATOM   309  N  NE2   . GLN A 1 39  ? 115.626 110.198 159.058 1.00 65.77  ? 39  GLN A NE2   1 
ATOM   310  N  N     . GLN A 1 40  ? 118.626 111.357 163.365 1.00 54.56  ? 40  GLN A N     1 
ATOM   311  C  CA    . GLN A 1 40  ? 118.409 111.020 164.768 1.00 55.67  ? 40  GLN A CA    1 
ATOM   312  C  C     . GLN A 1 40  ? 119.062 112.040 165.693 1.00 53.46  ? 40  GLN A C     1 
ATOM   313  O  O     . GLN A 1 40  ? 118.465 112.448 166.696 1.00 53.15  ? 40  GLN A O     1 
ATOM   314  C  CB    . GLN A 1 40  ? 118.937 109.615 165.053 1.00 63.52  ? 40  GLN A CB    1 
ATOM   315  C  CG    . GLN A 1 40  ? 118.615 108.613 163.960 1.00 70.98  ? 40  GLN A CG    1 
ATOM   316  C  CD    . GLN A 1 40  ? 117.439 107.724 164.308 1.00 81.27  ? 40  GLN A CD    1 
ATOM   317  O  OE1   . GLN A 1 40  ? 117.504 106.926 165.240 1.00 89.53  ? 40  GLN A OE1   1 
ATOM   318  N  NE2   . GLN A 1 40  ? 116.350 107.862 163.559 1.00 78.82  ? 40  GLN A NE2   1 
ATOM   319  N  N     . ASN A 1 41  ? 120.283 112.468 165.370 1.00 47.16  ? 41  ASN A N     1 
ATOM   320  C  CA    . ASN A 1 41  ? 120.964 113.450 166.206 1.00 47.12  ? 41  ASN A CA    1 
ATOM   321  C  C     . ASN A 1 41  ? 120.265 114.801 166.152 1.00 53.80  ? 41  ASN A C     1 
ATOM   322  O  O     . ASN A 1 41  ? 120.159 115.490 167.170 1.00 62.55  ? 41  ASN A O     1 
ATOM   323  C  CB    . ASN A 1 41  ? 122.424 113.578 165.779 1.00 54.01  ? 41  ASN A CB    1 
ATOM   324  C  CG    . ASN A 1 41  ? 123.218 112.319 166.049 1.00 68.45  ? 41  ASN A CG    1 
ATOM   325  O  OD1   . ASN A 1 41  ? 122.964 111.609 167.021 1.00 73.93  ? 41  ASN A OD1   1 
ATOM   326  N  ND2   . ASN A 1 41  ? 124.187 112.033 165.189 1.00 72.02  ? 41  ASN A ND2   1 
ATOM   327  N  N     . MET A 1 42  ? 119.773 115.194 164.976 1.00 51.86  ? 42  MET A N     1 
ATOM   328  C  CA    . MET A 1 42  ? 119.019 116.437 164.863 1.00 43.78  ? 42  MET A CA    1 
ATOM   329  C  C     . MET A 1 42  ? 117.737 116.385 165.679 1.00 43.14  ? 42  MET A C     1 
ATOM   330  O  O     . MET A 1 42  ? 117.374 117.361 166.344 1.00 45.32  ? 42  MET A O     1 
ATOM   331  C  CB    . MET A 1 42  ? 118.688 116.707 163.402 1.00 44.46  ? 42  MET A CB    1 
ATOM   332  C  CG    . MET A 1 42  ? 119.878 116.983 162.523 1.00 54.88  ? 42  MET A CG    1 
ATOM   333  S  SD    . MET A 1 42  ? 119.306 117.801 161.043 1.00 50.53  ? 42  MET A SD    1 
ATOM   334  C  CE    . MET A 1 42  ? 117.779 116.926 160.821 1.00 42.53  ? 42  MET A CE    1 
ATOM   335  N  N     . LEU A 1 43  ? 117.023 115.260 165.619 1.00 47.83  ? 43  LEU A N     1 
ATOM   336  C  CA    . LEU A 1 43  ? 115.797 115.122 166.396 1.00 46.01  ? 43  LEU A CA    1 
ATOM   337  C  C     . LEU A 1 43  ? 116.085 115.151 167.890 1.00 52.28  ? 43  LEU A C     1 
ATOM   338  O  O     . LEU A 1 43  ? 115.325 115.741 168.665 1.00 54.02  ? 43  LEU A O     1 
ATOM   339  C  CB    . LEU A 1 43  ? 115.081 113.831 166.010 1.00 41.52  ? 43  LEU A CB    1 
ATOM   340  C  CG    . LEU A 1 43  ? 113.834 114.009 165.152 1.00 39.51  ? 43  LEU A CG    1 
ATOM   341  C  CD1   . LEU A 1 43  ? 113.439 112.691 164.529 1.00 46.59  ? 43  LEU A CD1   1 
ATOM   342  C  CD2   . LEU A 1 43  ? 112.708 114.563 165.991 1.00 45.97  ? 43  LEU A CD2   1 
ATOM   343  N  N     . ALA A 1 44  ? 117.176 114.510 168.317 1.00 52.58  ? 44  ALA A N     1 
ATOM   344  C  CA    . ALA A 1 44  ? 117.538 114.533 169.728 1.00 51.99  ? 44  ALA A CA    1 
ATOM   345  C  C     . ALA A 1 44  ? 118.075 115.887 170.170 1.00 50.36  ? 44  ALA A C     1 
ATOM   346  O  O     . ALA A 1 44  ? 118.054 116.186 171.367 1.00 54.97  ? 44  ALA A O     1 
ATOM   347  C  CB    . ALA A 1 44  ? 118.570 113.447 170.024 1.00 56.87  ? 44  ALA A CB    1 
ATOM   348  N  N     . TYR A 1 45  ? 118.565 116.704 169.240 1.00 47.19  ? 45  TYR A N     1 
ATOM   349  C  CA    . TYR A 1 45  ? 119.086 118.022 169.578 1.00 50.74  ? 45  TYR A CA    1 
ATOM   350  C  C     . TYR A 1 45  ? 117.987 119.076 169.643 1.00 55.79  ? 45  TYR A C     1 
ATOM   351  O  O     . TYR A 1 45  ? 117.864 119.783 170.648 1.00 62.55  ? 45  TYR A O     1 
ATOM   352  C  CB    . TYR A 1 45  ? 120.155 118.433 168.562 1.00 52.32  ? 45  TYR A CB    1 
ATOM   353  C  CG    . TYR A 1 45  ? 120.646 119.852 168.721 1.00 56.35  ? 45  TYR A CG    1 
ATOM   354  C  CD1   . TYR A 1 45  ? 121.469 120.207 169.779 1.00 56.85  ? 45  TYR A CD1   1 
ATOM   355  C  CD2   . TYR A 1 45  ? 120.295 120.833 167.808 1.00 54.43  ? 45  TYR A CD2   1 
ATOM   356  C  CE1   . TYR A 1 45  ? 121.921 121.499 169.924 1.00 55.03  ? 45  TYR A CE1   1 
ATOM   357  C  CE2   . TYR A 1 45  ? 120.744 122.126 167.948 1.00 56.36  ? 45  TYR A CE2   1 
ATOM   358  C  CZ    . TYR A 1 45  ? 121.555 122.453 169.006 1.00 60.65  ? 45  TYR A CZ    1 
ATOM   359  O  OH    . TYR A 1 45  ? 122.004 123.743 169.146 1.00 74.36  ? 45  TYR A OH    1 
ATOM   360  N  N     . THR A 1 46  ? 117.181 119.197 168.587 1.00 52.38  ? 46  THR A N     1 
ATOM   361  C  CA    . THR A 1 46  ? 116.127 120.206 168.579 1.00 50.01  ? 46  THR A CA    1 
ATOM   362  C  C     . THR A 1 46  ? 115.010 119.836 169.548 1.00 55.35  ? 46  THR A C     1 
ATOM   363  O  O     . THR A 1 46  ? 114.744 120.559 170.514 1.00 65.63  ? 46  THR A O     1 
ATOM   364  C  CB    . THR A 1 46  ? 115.575 120.385 167.165 1.00 47.91  ? 46  THR A CB    1 
ATOM   365  O  OG1   . THR A 1 46  ? 116.559 121.024 166.345 1.00 51.25  ? 46  THR A OG1   1 
ATOM   366  C  CG2   . THR A 1 46  ? 114.326 121.242 167.192 1.00 45.92  ? 46  THR A CG2   1 
ATOM   367  N  N     . PHE A 1 47  ? 114.351 118.707 169.310 1.00 51.08  ? 47  PHE A N     1 
ATOM   368  C  CA    . PHE A 1 47  ? 113.295 118.224 170.199 1.00 48.38  ? 47  PHE A CA    1 
ATOM   369  C  C     . PHE A 1 47  ? 113.860 117.337 171.304 1.00 60.20  ? 47  PHE A C     1 
ATOM   370  O  O     . PHE A 1 47  ? 113.397 116.222 171.528 1.00 64.91  ? 47  PHE A O     1 
ATOM   371  C  CB    . PHE A 1 47  ? 112.235 117.483 169.394 1.00 44.34  ? 47  PHE A CB    1 
ATOM   372  C  CG    . PHE A 1 47  ? 111.653 118.287 168.268 1.00 49.63  ? 47  PHE A CG    1 
ATOM   373  C  CD1   . PHE A 1 47  ? 110.785 119.332 168.524 1.00 58.78  ? 47  PHE A CD1   1 
ATOM   374  C  CD2   . PHE A 1 47  ? 111.967 117.993 166.954 1.00 45.11  ? 47  PHE A CD2   1 
ATOM   375  C  CE1   . PHE A 1 47  ? 110.247 120.070 167.491 1.00 52.88  ? 47  PHE A CE1   1 
ATOM   376  C  CE2   . PHE A 1 47  ? 111.431 118.729 165.919 1.00 37.27  ? 47  PHE A CE2   1 
ATOM   377  C  CZ    . PHE A 1 47  ? 110.571 119.768 166.187 1.00 42.46  ? 47  PHE A CZ    1 
ATOM   378  N  N     . GLY A 1 48  ? 114.871 117.834 172.009 1.00 62.34  ? 48  GLY A N     1 
ATOM   379  C  CA    . GLY A 1 48  ? 115.489 117.063 173.069 1.00 62.06  ? 48  GLY A CA    1 
ATOM   380  C  C     . GLY A 1 48  ? 114.788 117.227 174.399 1.00 65.04  ? 48  GLY A C     1 
ATOM   381  O  O     . GLY A 1 48  ? 114.877 116.360 175.272 1.00 67.39  ? 48  GLY A O     1 
ATOM   382  N  N     . GLU A 1 49  ? 114.087 118.344 174.562 1.00 66.21  ? 49  GLU A N     1 
ATOM   383  C  CA    . GLU A 1 49  ? 113.331 118.602 175.777 1.00 69.36  ? 49  GLU A CA    1 
ATOM   384  C  C     . GLU A 1 49  ? 111.971 119.222 175.504 1.00 75.52  ? 49  GLU A C     1 
ATOM   385  O  O     . GLU A 1 49  ? 111.261 119.551 176.459 1.00 79.09  ? 49  GLU A O     1 
ATOM   386  C  CB    . GLU A 1 49  ? 114.129 119.517 176.718 1.00 75.78  ? 49  GLU A CB    1 
ATOM   387  C  CG    . GLU A 1 49  ? 114.750 120.717 176.025 1.00 84.45  ? 49  GLU A CG    1 
ATOM   388  C  CD    . GLU A 1 49  ? 115.976 121.239 176.746 1.00 90.62  ? 49  GLU A CD    1 
ATOM   389  O  OE1   . GLU A 1 49  ? 116.387 120.621 177.750 1.00 88.99  ? 49  GLU A OE1   1 
ATOM   390  O  OE2   . GLU A 1 49  ? 116.528 122.269 176.309 1.00 87.89  ? 49  GLU A OE2   1 
ATOM   391  N  N     . VAL A 1 50  ? 111.588 119.394 174.242 1.00 69.59  ? 50  VAL A N     1 
ATOM   392  C  CA    . VAL A 1 50  ? 110.311 119.984 173.869 1.00 61.65  ? 50  VAL A CA    1 
ATOM   393  C  C     . VAL A 1 50  ? 109.635 119.055 172.873 1.00 63.97  ? 50  VAL A C     1 
ATOM   394  O  O     . VAL A 1 50  ? 110.214 118.733 171.829 1.00 67.88  ? 50  VAL A O     1 
ATOM   395  C  CB    . VAL A 1 50  ? 110.482 121.389 173.269 1.00 57.40  ? 50  VAL A CB    1 
ATOM   396  C  CG1   . VAL A 1 50  ? 111.771 121.470 172.474 1.00 61.13  ? 50  VAL A CG1   1 
ATOM   397  C  CG2   . VAL A 1 50  ? 109.299 121.732 172.385 1.00 59.32  ? 50  VAL A CG2   1 
ATOM   398  N  N     . ILE A 1 51  ? 108.427 118.620 173.197 1.00 63.05  ? 51  ILE A N     1 
ATOM   399  C  CA    . ILE A 1 51  ? 107.576 117.865 172.282 1.00 62.46  ? 51  ILE A CA    1 
ATOM   400  C  C     . ILE A 1 51  ? 106.437 118.780 171.857 1.00 69.96  ? 51  ILE A C     1 
ATOM   401  O  O     . ILE A 1 51  ? 105.748 119.342 172.720 1.00 75.98  ? 51  ILE A O     1 
ATOM   402  C  CB    . ILE A 1 51  ? 107.043 116.577 172.926 1.00 56.44  ? 51  ILE A CB    1 
ATOM   403  C  CG1   . ILE A 1 51  ? 108.042 115.443 172.728 1.00 62.16  ? 51  ILE A CG1   1 
ATOM   404  C  CG2   . ILE A 1 51  ? 105.718 116.189 172.307 1.00 59.69  ? 51  ILE A CG2   1 
ATOM   405  C  CD1   . ILE A 1 51  ? 108.245 115.074 171.283 1.00 58.74  ? 51  ILE A CD1   1 
ATOM   406  N  N     . PRO A 1 52  ? 106.215 118.986 170.560 1.00 62.16  ? 52  PRO A N     1 
ATOM   407  C  CA    . PRO A 1 52  ? 105.158 119.904 170.130 1.00 61.05  ? 52  PRO A CA    1 
ATOM   408  C  C     . PRO A 1 52  ? 103.794 119.437 170.613 1.00 66.90  ? 52  PRO A C     1 
ATOM   409  O  O     . PRO A 1 52  ? 103.524 118.240 170.718 1.00 71.81  ? 52  PRO A O     1 
ATOM   410  C  CB    . PRO A 1 52  ? 105.255 119.867 168.600 1.00 62.40  ? 52  PRO A CB    1 
ATOM   411  C  CG    . PRO A 1 52  ? 106.615 119.321 168.311 1.00 60.55  ? 52  PRO A CG    1 
ATOM   412  C  CD    . PRO A 1 52  ? 106.912 118.372 169.419 1.00 57.92  ? 52  PRO A CD    1 
ATOM   413  N  N     . GLY A 1 53  ? 102.938 120.405 170.935 1.00 67.56  ? 53  GLY A N     1 
ATOM   414  C  CA    . GLY A 1 53  ? 101.618 120.109 171.444 1.00 72.84  ? 53  GLY A CA    1 
ATOM   415  C  C     . GLY A 1 53  ? 101.561 119.810 172.924 1.00 79.80  ? 53  GLY A C     1 
ATOM   416  O  O     . GLY A 1 53  ? 100.460 119.761 173.487 1.00 86.95  ? 53  GLY A O     1 
ATOM   417  N  N     . PHE A 1 54  ? 102.708 119.608 173.575 1.00 73.54  ? 54  PHE A N     1 
ATOM   418  C  CA    . PHE A 1 54  ? 102.771 119.381 175.013 1.00 72.44  ? 54  PHE A CA    1 
ATOM   419  C  C     . PHE A 1 54  ? 103.911 120.176 175.634 1.00 73.82  ? 54  PHE A C     1 
ATOM   420  O  O     . PHE A 1 54  ? 104.525 119.735 176.611 1.00 78.61  ? 54  PHE A O     1 
ATOM   421  C  CB    . PHE A 1 54  ? 102.918 117.894 175.330 1.00 68.10  ? 54  PHE A CB    1 
ATOM   422  C  CG    . PHE A 1 54  ? 101.736 117.070 174.913 1.00 72.38  ? 54  PHE A CG    1 
ATOM   423  C  CD1   . PHE A 1 54  ? 101.662 116.534 173.641 1.00 70.62  ? 54  PHE A CD1   1 
ATOM   424  C  CD2   . PHE A 1 54  ? 100.692 116.841 175.791 1.00 79.16  ? 54  PHE A CD2   1 
ATOM   425  C  CE1   . PHE A 1 54  ? 100.573 115.781 173.255 1.00 71.36  ? 54  PHE A CE1   1 
ATOM   426  C  CE2   . PHE A 1 54  ? 99.602  116.088 175.409 1.00 77.05  ? 54  PHE A CE2   1 
ATOM   427  C  CZ    . PHE A 1 54  ? 99.543  115.558 174.141 1.00 72.33  ? 54  PHE A CZ    1 
ATOM   428  N  N     . ALA A 1 55  ? 104.201 121.347 175.072 1.00 68.82  ? 55  ALA A N     1 
ATOM   429  C  CA    . ALA A 1 55  ? 105.252 122.229 175.556 1.00 66.76  ? 55  ALA A CA    1 
ATOM   430  C  C     . ALA A 1 55  ? 104.668 123.609 175.822 1.00 75.56  ? 55  ALA A C     1 
ATOM   431  O  O     . ALA A 1 55  ? 103.444 123.759 175.893 1.00 75.46  ? 55  ALA A O     1 
ATOM   432  C  CB    . ALA A 1 55  ? 106.400 122.312 174.550 1.00 63.13  ? 55  ALA A CB    1 
ATOM   433  N  N     . SER A 1 56  ? 105.531 124.610 176.000 1.00 74.19  ? 56  SER A N     1 
ATOM   434  C  CA    . SER A 1 56  ? 105.071 125.972 176.239 1.00 73.56  ? 56  SER A CA    1 
ATOM   435  C  C     . SER A 1 56  ? 104.080 126.403 175.164 1.00 70.61  ? 56  SER A C     1 
ATOM   436  O  O     . SER A 1 56  ? 104.115 125.925 174.027 1.00 70.18  ? 56  SER A O     1 
ATOM   437  C  CB    . SER A 1 56  ? 106.259 126.933 176.276 1.00 73.11  ? 56  SER A CB    1 
ATOM   438  O  OG    . SER A 1 56  ? 107.111 126.730 175.164 1.00 73.31  ? 56  SER A OG    1 
ATOM   439  N  N     . ALA A 1 57  ? 103.190 127.328 175.535 1.00 69.80  ? 57  ALA A N     1 
ATOM   440  C  CA    . ALA A 1 57  ? 102.079 127.693 174.665 1.00 69.59  ? 57  ALA A CA    1 
ATOM   441  C  C     . ALA A 1 57  ? 102.534 128.368 173.379 1.00 68.07  ? 57  ALA A C     1 
ATOM   442  O  O     . ALA A 1 57  ? 101.734 128.498 172.447 1.00 71.70  ? 57  ALA A O     1 
ATOM   443  C  CB    . ALA A 1 57  ? 101.106 128.603 175.413 1.00 70.28  ? 57  ALA A CB    1 
ATOM   444  N  N     . GLY A 1 58  ? 103.791 128.810 173.306 1.00 62.67  ? 58  GLY A N     1 
ATOM   445  C  CA    . GLY A 1 58  ? 104.296 129.378 172.071 1.00 63.47  ? 58  GLY A CA    1 
ATOM   446  C  C     . GLY A 1 58  ? 104.645 128.358 171.011 1.00 63.89  ? 58  GLY A C     1 
ATOM   447  O  O     . GLY A 1 58  ? 104.709 128.707 169.829 1.00 70.68  ? 58  GLY A O     1 
ATOM   448  N  N     . ILE A 1 59  ? 104.868 127.108 171.405 1.00 56.06  ? 59  ILE A N     1 
ATOM   449  C  CA    . ILE A 1 59  ? 105.208 126.043 170.473 1.00 56.22  ? 59  ILE A CA    1 
ATOM   450  C  C     . ILE A 1 59  ? 103.974 125.268 170.029 1.00 62.50  ? 59  ILE A C     1 
ATOM   451  O  O     . ILE A 1 59  ? 103.893 124.832 168.880 1.00 62.11  ? 59  ILE A O     1 
ATOM   452  C  CB    . ILE A 1 59  ? 106.259 125.106 171.106 1.00 52.26  ? 59  ILE A CB    1 
ATOM   453  C  CG1   . ILE A 1 59  ? 107.453 125.920 171.602 1.00 55.44  ? 59  ILE A CG1   1 
ATOM   454  C  CG2   . ILE A 1 59  ? 106.717 124.056 170.112 1.00 56.74  ? 59  ILE A CG2   1 
ATOM   455  C  CD1   . ILE A 1 59  ? 108.352 125.168 172.545 1.00 59.30  ? 59  ILE A CD1   1 
ATOM   456  N  N     . ASN A 1 60  ? 103.003 125.087 170.928 1.00 61.96  ? 60  ASN A N     1 
ATOM   457  C  CA    . ASN A 1 60  ? 101.767 124.410 170.552 1.00 59.51  ? 60  ASN A CA    1 
ATOM   458  C  C     . ASN A 1 60  ? 101.009 125.194 169.489 1.00 64.57  ? 60  ASN A C     1 
ATOM   459  O  O     . ASN A 1 60  ? 100.490 124.612 168.531 1.00 70.16  ? 60  ASN A O     1 
ATOM   460  C  CB    . ASN A 1 60  ? 100.888 124.197 171.783 1.00 63.65  ? 60  ASN A CB    1 
ATOM   461  C  CG    . ASN A 1 60  ? 101.642 123.575 172.938 1.00 72.62  ? 60  ASN A CG    1 
ATOM   462  O  OD1   . ASN A 1 60  ? 102.654 122.904 172.744 1.00 73.98  ? 60  ASN A OD1   1 
ATOM   463  N  ND2   . ASN A 1 60  ? 101.150 123.794 174.151 1.00 73.50  ? 60  ASN A ND2   1 
ATOM   464  N  N     . GLY A 1 61  ? 100.931 126.514 169.642 1.00 66.24  ? 61  GLY A N     1 
ATOM   465  C  CA    . GLY A 1 61  ? 100.217 127.339 168.687 1.00 64.74  ? 61  GLY A CA    1 
ATOM   466  C  C     . GLY A 1 61  ? 101.008 127.747 167.464 1.00 65.86  ? 61  GLY A C     1 
ATOM   467  O  O     . GLY A 1 61  ? 100.429 128.315 166.534 1.00 66.93  ? 61  GLY A O     1 
ATOM   468  N  N     . MET A 1 62  ? 102.309 127.473 167.442 1.00 66.89  ? 62  MET A N     1 
ATOM   469  C  CA    . MET A 1 62  ? 103.134 127.848 166.304 1.00 64.40  ? 62  MET A CA    1 
ATOM   470  C  C     . MET A 1 62  ? 102.759 127.027 165.077 1.00 62.55  ? 62  MET A C     1 
ATOM   471  O  O     . MET A 1 62  ? 102.375 125.860 165.177 1.00 62.65  ? 62  MET A O     1 
ATOM   472  C  CB    . MET A 1 62  ? 104.613 127.657 166.632 1.00 63.74  ? 62  MET A CB    1 
ATOM   473  C  CG    . MET A 1 62  ? 105.560 128.241 165.601 1.00 71.03  ? 62  MET A CG    1 
ATOM   474  S  SD    . MET A 1 62  ? 107.149 128.701 166.306 1.00 85.61  ? 62  MET A SD    1 
ATOM   475  C  CE    . MET A 1 62  ? 107.805 127.088 166.701 1.00 66.45  ? 62  MET A CE    1 
ATOM   476  N  N     . ASP A 1 63  ? 102.891 127.661 163.915 1.00 60.33  ? 63  ASP A N     1 
ATOM   477  C  CA    . ASP A 1 63  ? 102.566 126.994 162.636 1.00 61.62  ? 63  ASP A CA    1 
ATOM   478  C  C     . ASP A 1 63  ? 103.376 125.715 162.533 1.00 65.47  ? 63  ASP A C     1 
ATOM   479  O  O     . ASP A 1 63  ? 104.578 125.756 162.800 1.00 67.78  ? 63  ASP A O     1 
ATOM   480  C  CB    . ASP A 1 63  ? 102.910 127.902 161.464 1.00 30.00  ? 63  ASP A CB    1 
ATOM   481  C  CG    . ASP A 1 63  ? 102.143 127.580 160.197 1.00 30.00  ? 63  ASP A CG    1 
ATOM   482  O  OD1   . ASP A 1 63  ? 101.159 126.825 160.285 1.00 30.00  ? 63  ASP A OD1   1 
ATOM   483  O  OD2   . ASP A 1 63  ? 102.538 128.095 159.136 1.00 30.00  ? 63  ASP A OD2   1 
ATOM   484  N  N     . TYR A 1 64  ? 102.747 124.636 162.101 1.00 62.77  ? 64  TYR A N     1 
ATOM   485  C  CA    . TYR A 1 64  ? 103.432 123.349 162.062 1.00 57.19  ? 64  TYR A CA    1 
ATOM   486  C  C     . TYR A 1 64  ? 104.569 123.341 161.050 1.00 51.98  ? 64  TYR A C     1 
ATOM   487  O  O     . TYR A 1 64  ? 105.573 122.653 161.258 1.00 52.44  ? 64  TYR A O     1 
ATOM   488  C  CB    . TYR A 1 64  ? 102.438 122.233 161.747 1.00 54.84  ? 64  TYR A CB    1 
ATOM   489  C  CG    . TYR A 1 64  ? 102.705 120.952 162.502 1.00 56.24  ? 64  TYR A CG    1 
ATOM   490  C  CD1   . TYR A 1 64  ? 103.919 120.736 163.133 1.00 55.74  ? 64  TYR A CD1   1 
ATOM   491  C  CD2   . TYR A 1 64  ? 101.745 119.958 162.580 1.00 56.51  ? 64  TYR A CD2   1 
ATOM   492  C  CE1   . TYR A 1 64  ? 104.165 119.570 163.825 1.00 53.26  ? 64  TYR A CE1   1 
ATOM   493  C  CE2   . TYR A 1 64  ? 101.984 118.789 163.266 1.00 57.52  ? 64  TYR A CE2   1 
ATOM   494  C  CZ    . TYR A 1 64  ? 103.195 118.601 163.886 1.00 58.71  ? 64  TYR A CZ    1 
ATOM   495  O  OH    . TYR A 1 64  ? 103.437 117.437 164.572 1.00 67.37  ? 64  TYR A OH    1 
ATOM   496  N  N     . ARG A 1 65  ? 104.435 124.094 159.956 1.00 52.95  ? 65  ARG A N     1 
ATOM   497  C  CA    . ARG A 1 65  ? 105.489 124.130 158.951 1.00 53.54  ? 65  ARG A CA    1 
ATOM   498  C  C     . ARG A 1 65  ? 106.782 124.729 159.487 1.00 57.24  ? 65  ARG A C     1 
ATOM   499  O  O     . ARG A 1 65  ? 107.834 124.554 158.863 1.00 60.43  ? 65  ARG A O     1 
ATOM   500  C  CB    . ARG A 1 65  ? 105.028 124.916 157.724 1.00 61.33  ? 65  ARG A CB    1 
ATOM   501  C  CG    . ARG A 1 65  ? 104.256 124.090 156.713 1.00 67.40  ? 65  ARG A CG    1 
ATOM   502  C  CD    . ARG A 1 65  ? 103.793 124.943 155.546 1.00 71.44  ? 65  ARG A CD    1 
ATOM   503  N  NE    . ARG A 1 65  ? 103.178 126.186 155.993 1.00 66.08  ? 65  ARG A NE    1 
ATOM   504  C  CZ    . ARG A 1 65  ? 101.954 126.279 156.492 1.00 71.40  ? 65  ARG A CZ    1 
ATOM   505  N  NH1   . ARG A 1 65  ? 101.176 125.217 156.617 1.00 76.23  ? 65  ARG A NH1   1 
ATOM   506  N  NH2   . ARG A 1 65  ? 101.500 127.468 156.877 1.00 75.93  ? 65  ARG A NH2   1 
ATOM   507  N  N     . ASP A 1 66  ? 106.730 125.432 160.617 1.00 55.86  ? 66  ASP A N     1 
ATOM   508  C  CA    . ASP A 1 66  ? 107.939 125.946 161.248 1.00 53.57  ? 66  ASP A CA    1 
ATOM   509  C  C     . ASP A 1 66  ? 108.487 125.003 162.307 1.00 56.38  ? 66  ASP A C     1 
ATOM   510  O  O     . ASP A 1 66  ? 109.705 124.951 162.508 1.00 60.41  ? 66  ASP A O     1 
ATOM   511  C  CB    . ASP A 1 66  ? 107.671 127.317 161.872 1.00 58.61  ? 66  ASP A CB    1 
ATOM   512  C  CG    . ASP A 1 66  ? 107.245 128.348 160.848 1.00 73.47  ? 66  ASP A CG    1 
ATOM   513  O  OD1   . ASP A 1 66  ? 107.690 128.249 159.686 1.00 72.87  ? 66  ASP A OD1   1 
ATOM   514  O  OD2   . ASP A 1 66  ? 106.467 129.258 161.205 1.00 80.94  ? 66  ASP A OD2   1 
ATOM   515  N  N     . VAL A 1 67  ? 107.618 124.260 162.995 1.00 53.37  ? 67  VAL A N     1 
ATOM   516  C  CA    . VAL A 1 67  ? 108.089 123.229 163.915 1.00 50.20  ? 67  VAL A CA    1 
ATOM   517  C  C     . VAL A 1 67  ? 108.738 122.088 163.140 1.00 51.46  ? 67  VAL A C     1 
ATOM   518  O  O     . VAL A 1 67  ? 109.817 121.606 163.500 1.00 49.38  ? 67  VAL A O     1 
ATOM   519  C  CB    . VAL A 1 67  ? 106.934 122.729 164.798 1.00 44.78  ? 67  VAL A CB    1 
ATOM   520  C  CG1   . VAL A 1 67  ? 107.469 121.864 165.916 1.00 44.46  ? 67  VAL A CG1   1 
ATOM   521  C  CG2   . VAL A 1 67  ? 106.153 123.901 165.358 1.00 50.56  ? 67  VAL A CG2   1 
ATOM   522  N  N     . ILE A 1 68  ? 108.091 121.643 162.065 1.00 51.09  ? 68  ILE A N     1 
ATOM   523  C  CA    . ILE A 1 68  ? 108.666 120.644 161.162 1.00 40.75  ? 68  ILE A CA    1 
ATOM   524  C  C     . ILE A 1 68  ? 109.502 121.419 160.149 1.00 46.46  ? 68  ILE A C     1 
ATOM   525  O  O     . ILE A 1 68  ? 109.017 121.848 159.102 1.00 56.88  ? 68  ILE A O     1 
ATOM   526  C  CB    . ILE A 1 68  ? 107.598 119.787 160.494 1.00 42.97  ? 68  ILE A CB    1 
ATOM   527  C  CG1   . ILE A 1 68  ? 106.716 119.115 161.543 1.00 43.42  ? 68  ILE A CG1   1 
ATOM   528  C  CG2   . ILE A 1 68  ? 108.245 118.750 159.603 1.00 45.36  ? 68  ILE A CG2   1 
ATOM   529  C  CD1   . ILE A 1 68  ? 107.487 118.403 162.619 1.00 49.46  ? 68  ILE A CD1   1 
ATOM   530  N  N     . GLY A 1 69  ? 110.776 121.598 160.468 1.00 43.80  ? 69  GLY A N     1 
ATOM   531  C  CA    . GLY A 1 69  ? 111.654 122.402 159.647 1.00 48.16  ? 69  GLY A CA    1 
ATOM   532  C  C     . GLY A 1 69  ? 112.613 123.192 160.507 1.00 50.87  ? 69  GLY A C     1 
ATOM   533  O  O     . GLY A 1 69  ? 113.576 123.780 160.008 1.00 54.94  ? 69  GLY A O     1 
ATOM   534  N  N     . ARG A 1 70  ? 112.342 123.223 161.810 1.00 42.77  ? 70  ARG A N     1 
ATOM   535  C  CA    . ARG A 1 70  ? 113.314 123.768 162.754 1.00 45.45  ? 70  ARG A CA    1 
ATOM   536  C  C     . ARG A 1 70  ? 114.594 122.944 162.824 1.00 51.60  ? 70  ARG A C     1 
ATOM   537  O  O     . ARG A 1 70  ? 115.684 123.543 162.815 1.00 63.24  ? 70  ARG A O     1 
ATOM   538  C  CB    . ARG A 1 70  ? 112.667 123.915 164.134 1.00 47.84  ? 70  ARG A CB    1 
ATOM   539  C  CG    . ARG A 1 70  ? 113.583 124.522 165.177 1.00 50.95  ? 70  ARG A CG    1 
ATOM   540  C  CD    . ARG A 1 70  ? 114.063 125.895 164.753 1.00 52.95  ? 70  ARG A CD    1 
ATOM   541  N  NE    . ARG A 1 70  ? 112.961 126.835 164.602 1.00 57.01  ? 70  ARG A NE    1 
ATOM   542  C  CZ    . ARG A 1 70  ? 112.645 127.765 165.492 1.00 61.77  ? 70  ARG A CZ    1 
ATOM   543  N  NH1   . ARG A 1 70  ? 113.328 127.904 166.616 1.00 59.05  ? 70  ARG A NH1   1 
ATOM   544  N  NH2   . ARG A 1 70  ? 111.621 128.577 165.246 1.00 69.57  ? 70  ARG A NH2   1 
ATOM   545  N  N     . PRO A 1 71  ? 114.558 121.607 162.923 1.00 44.99  ? 71  PRO A N     1 
ATOM   546  C  CA    . PRO A 1 71  ? 115.824 120.859 162.966 1.00 37.28  ? 71  PRO A CA    1 
ATOM   547  C  C     . PRO A 1 71  ? 116.694 121.057 161.741 1.00 44.40  ? 71  PRO A C     1 
ATOM   548  O  O     . PRO A 1 71  ? 117.923 121.074 161.868 1.00 54.47  ? 71  PRO A O     1 
ATOM   549  C  CB    . PRO A 1 71  ? 115.366 119.401 163.099 1.00 37.36  ? 71  PRO A CB    1 
ATOM   550  C  CG    . PRO A 1 71  ? 114.020 119.481 163.682 1.00 43.09  ? 71  PRO A CG    1 
ATOM   551  C  CD    . PRO A 1 71  ? 113.404 120.709 163.108 1.00 49.33  ? 71  PRO A CD    1 
ATOM   552  N  N     . VAL A 1 72  ? 116.103 121.209 160.556 1.00 45.79  ? 72  VAL A N     1 
ATOM   553  C  CA    . VAL A 1 72  ? 116.912 121.444 159.364 1.00 48.46  ? 72  VAL A CA    1 
ATOM   554  C  C     . VAL A 1 72  ? 117.602 122.800 159.448 1.00 49.50  ? 72  VAL A C     1 
ATOM   555  O  O     . VAL A 1 72  ? 118.768 122.942 159.062 1.00 48.06  ? 72  VAL A O     1 
ATOM   556  C  CB    . VAL A 1 72  ? 116.053 121.319 158.095 1.00 39.73  ? 72  VAL A CB    1 
ATOM   557  C  CG1   . VAL A 1 72  ? 116.941 121.281 156.871 1.00 32.18  ? 72  VAL A CG1   1 
ATOM   558  C  CG2   . VAL A 1 72  ? 115.189 120.076 158.163 1.00 37.94  ? 72  VAL A CG2   1 
ATOM   559  N  N     . GLU A 1 73  ? 116.898 123.815 159.955 1.00 47.66  ? 73  GLU A N     1 
ATOM   560  C  CA    . GLU A 1 73  ? 117.524 125.118 160.157 1.00 48.51  ? 73  GLU A CA    1 
ATOM   561  C  C     . GLU A 1 73  ? 118.655 125.029 161.171 1.00 47.54  ? 73  GLU A C     1 
ATOM   562  O  O     . GLU A 1 73  ? 119.716 125.639 160.986 1.00 56.42  ? 73  GLU A O     1 
ATOM   563  C  CB    . GLU A 1 73  ? 116.483 126.139 160.610 1.00 47.54  ? 73  GLU A CB    1 
ATOM   564  C  CG    . GLU A 1 73  ? 115.357 126.364 159.621 1.00 58.44  ? 73  GLU A CG    1 
ATOM   565  C  CD    . GLU A 1 73  ? 114.438 127.494 160.038 1.00 80.10  ? 73  GLU A CD    1 
ATOM   566  O  OE1   . GLU A 1 73  ? 114.790 128.229 160.984 1.00 85.91  ? 73  GLU A OE1   1 
ATOM   567  O  OE2   . GLU A 1 73  ? 113.362 127.646 159.423 1.00 87.03  ? 73  GLU A OE2   1 
ATOM   568  N  N     . ASN A 1 74  ? 118.446 124.273 162.251 1.00 42.94  ? 74  ASN A N     1 
ATOM   569  C  CA    . ASN A 1 74  ? 119.497 124.108 163.248 1.00 45.33  ? 74  ASN A CA    1 
ATOM   570  C  C     . ASN A 1 74  ? 120.716 123.418 162.652 1.00 50.07  ? 74  ASN A C     1 
ATOM   571  O  O     . ASN A 1 74  ? 121.855 123.813 162.924 1.00 63.51  ? 74  ASN A O     1 
ATOM   572  C  CB    . ASN A 1 74  ? 118.966 123.324 164.447 1.00 43.98  ? 74  ASN A CB    1 
ATOM   573  C  CG    . ASN A 1 74  ? 117.961 124.114 165.259 1.00 48.86  ? 74  ASN A CG    1 
ATOM   574  O  OD1   . ASN A 1 74  ? 117.830 125.325 165.096 1.00 49.54  ? 74  ASN A OD1   1 
ATOM   575  N  ND2   . ASN A 1 74  ? 117.247 123.431 166.144 1.00 51.16  ? 74  ASN A ND2   1 
ATOM   576  N  N     . ALA A 1 75  ? 120.499 122.391 161.829 1.00 43.93  ? 75  ALA A N     1 
ATOM   577  C  CA    . ALA A 1 75  ? 121.620 121.704 161.196 1.00 42.71  ? 75  ALA A CA    1 
ATOM   578  C  C     . ALA A 1 75  ? 122.352 122.611 160.223 1.00 47.30  ? 75  ALA A C     1 
ATOM   579  O  O     . ALA A 1 75  ? 123.583 122.575 160.142 1.00 54.43  ? 75  ALA A O     1 
ATOM   580  C  CB    . ALA A 1 75  ? 121.143 120.457 160.469 1.00 42.45  ? 75  ALA A CB    1 
ATOM   581  N  N     . VAL A 1 76  ? 121.614 123.407 159.450 1.00 41.64  ? 76  VAL A N     1 
ATOM   582  C  CA    . VAL A 1 76  ? 122.257 124.310 158.503 1.00 42.63  ? 76  VAL A CA    1 
ATOM   583  C  C     . VAL A 1 76  ? 123.100 125.338 159.244 1.00 51.49  ? 76  VAL A C     1 
ATOM   584  O  O     . VAL A 1 76  ? 124.241 125.623 158.857 1.00 53.75  ? 76  VAL A O     1 
ATOM   585  C  CB    . VAL A 1 76  ? 121.203 124.974 157.601 1.00 40.98  ? 76  VAL A CB    1 
ATOM   586  C  CG1   . VAL A 1 76  ? 121.795 126.174 156.888 1.00 47.75  ? 76  VAL A CG1   1 
ATOM   587  C  CG2   . VAL A 1 76  ? 120.664 123.968 156.601 1.00 41.25  ? 76  VAL A CG2   1 
ATOM   588  N  N     . THR A 1 77  ? 122.563 125.898 160.331 1.00 51.21  ? 77  THR A N     1 
ATOM   589  C  CA    . THR A 1 77  ? 123.331 126.853 161.122 1.00 45.18  ? 77  THR A CA    1 
ATOM   590  C  C     . THR A 1 77  ? 124.561 126.200 161.740 1.00 51.43  ? 77  THR A C     1 
ATOM   591  O  O     . THR A 1 77  ? 125.647 126.791 161.746 1.00 64.86  ? 77  THR A O     1 
ATOM   592  C  CB    . THR A 1 77  ? 122.451 127.469 162.207 1.00 43.07  ? 77  THR A CB    1 
ATOM   593  O  OG1   . THR A 1 77  ? 121.179 127.819 161.651 1.00 56.08  ? 77  THR A OG1   1 
ATOM   594  C  CG2   . THR A 1 77  ? 123.104 128.717 162.760 1.00 50.28  ? 77  THR A CG2   1 
ATOM   595  N  N     . GLU A 1 78  ? 124.415 124.978 162.257 1.00 48.50  ? 78  GLU A N     1 
ATOM   596  C  CA    . GLU A 1 78  ? 125.552 124.281 162.850 1.00 46.68  ? 78  GLU A CA    1 
ATOM   597  C  C     . GLU A 1 78  ? 126.630 123.995 161.814 1.00 48.75  ? 78  GLU A C     1 
ATOM   598  O  O     . GLU A 1 78  ? 127.824 124.174 162.082 1.00 60.07  ? 78  GLU A O     1 
ATOM   599  C  CB    . GLU A 1 78  ? 125.078 122.986 163.507 1.00 47.77  ? 78  GLU A CB    1 
ATOM   600  C  CG    . GLU A 1 78  ? 126.080 122.355 164.453 1.00 54.35  ? 78  GLU A CG    1 
ATOM   601  C  CD    . GLU A 1 78  ? 126.798 121.174 163.838 1.00 62.41  ? 78  GLU A CD    1 
ATOM   602  O  OE1   . GLU A 1 78  ? 127.003 121.170 162.608 1.00 61.12  ? 78  GLU A OE1   1 
ATOM   603  O  OE2   . GLU A 1 78  ? 127.159 120.244 164.587 1.00 64.10  ? 78  GLU A OE2   1 
ATOM   604  N  N     . GLY A 1 79  ? 126.230 123.540 160.627 1.00 44.72  ? 79  GLY A N     1 
ATOM   605  C  CA    . GLY A 1 79  ? 127.202 123.268 159.583 1.00 51.89  ? 79  GLY A CA    1 
ATOM   606  C  C     . GLY A 1 79  ? 127.904 124.520 159.103 1.00 55.31  ? 79  GLY A C     1 
ATOM   607  O  O     . GLY A 1 79  ? 129.110 124.503 158.841 1.00 60.94  ? 79  GLY A O     1 
ATOM   608  N  N     . THR A 1 80  ? 127.164 125.624 158.976 1.00 50.56  ? 80  THR A N     1 
ATOM   609  C  CA    . THR A 1 80  ? 127.795 126.889 158.621 1.00 50.31  ? 80  THR A CA    1 
ATOM   610  C  C     . THR A 1 80  ? 128.767 127.335 159.705 1.00 54.99  ? 80  THR A C     1 
ATOM   611  O  O     . THR A 1 80  ? 129.822 127.906 159.408 1.00 62.19  ? 80  THR A O     1 
ATOM   612  C  CB    . THR A 1 80  ? 126.730 127.957 158.379 1.00 47.93  ? 80  THR A CB    1 
ATOM   613  O  OG1   . THR A 1 80  ? 125.797 127.489 157.398 1.00 51.69  ? 80  THR A OG1   1 
ATOM   614  C  CG2   . THR A 1 80  ? 127.366 129.240 157.882 1.00 49.00  ? 80  THR A CG2   1 
ATOM   615  N  N     . HIS A 1 81  ? 128.429 127.080 160.970 1.00 54.85  ? 81  HIS A N     1 
ATOM   616  C  CA    . HIS A 1 81  ? 129.313 127.460 162.066 1.00 55.89  ? 81  HIS A CA    1 
ATOM   617  C  C     . HIS A 1 81  ? 130.594 126.637 162.064 1.00 60.93  ? 81  HIS A C     1 
ATOM   618  O  O     . HIS A 1 81  ? 131.683 127.176 162.288 1.00 69.88  ? 81  HIS A O     1 
ATOM   619  C  CB    . HIS A 1 81  ? 128.580 127.311 163.398 1.00 57.53  ? 81  HIS A CB    1 
ATOM   620  C  CG    . HIS A 1 81  ? 129.487 127.284 164.588 1.00 67.59  ? 81  HIS A CG    1 
ATOM   621  N  ND1   . HIS A 1 81  ? 129.785 126.125 165.270 1.00 70.09  ? 81  HIS A ND1   1 
ATOM   622  C  CD2   . HIS A 1 81  ? 130.163 128.275 165.216 1.00 71.50  ? 81  HIS A CD2   1 
ATOM   623  C  CE1   . HIS A 1 81  ? 130.603 126.403 166.269 1.00 73.83  ? 81  HIS A CE1   1 
ATOM   624  N  NE2   . HIS A 1 81  ? 130.849 127.700 166.257 1.00 76.39  ? 81  HIS A NE2   1 
ATOM   625  N  N     . PHE A 1 82  ? 130.489 125.332 161.816 1.00 60.04  ? 82  PHE A N     1 
ATOM   626  C  CA    . PHE A 1 82  ? 131.670 124.475 161.857 1.00 59.17  ? 82  PHE A CA    1 
ATOM   627  C  C     . PHE A 1 82  ? 132.437 124.520 160.540 1.00 63.98  ? 82  PHE A C     1 
ATOM   628  O  O     . PHE A 1 82  ? 133.598 124.941 160.499 1.00 73.02  ? 82  PHE A O     1 
ATOM   629  C  CB    . PHE A 1 82  ? 131.268 123.039 162.198 1.00 60.19  ? 82  PHE A CB    1 
ATOM   630  C  CG    . PHE A 1 82  ? 131.080 122.797 163.665 1.00 62.79  ? 82  PHE A CG    1 
ATOM   631  C  CD1   . PHE A 1 82  ? 131.959 123.337 164.585 1.00 65.25  ? 82  PHE A CD1   1 
ATOM   632  C  CD2   . PHE A 1 82  ? 130.027 122.030 164.125 1.00 64.50  ? 82  PHE A CD2   1 
ATOM   633  C  CE1   . PHE A 1 82  ? 131.789 123.119 165.935 1.00 71.44  ? 82  PHE A CE1   1 
ATOM   634  C  CE2   . PHE A 1 82  ? 129.853 121.809 165.474 1.00 67.01  ? 82  PHE A CE2   1 
ATOM   635  C  CZ    . PHE A 1 82  ? 130.736 122.354 166.381 1.00 70.88  ? 82  PHE A CZ    1 
ATOM   636  N  N     . PHE A 1 83  ? 131.804 124.083 159.453 1.00 63.10  ? 83  PHE A N     1 
ATOM   637  C  CA    . PHE A 1 83  ? 132.436 124.083 158.134 1.00 60.32  ? 83  PHE A CA    1 
ATOM   638  C  C     . PHE A 1 83  ? 131.972 125.307 157.346 1.00 64.03  ? 83  PHE A C     1 
ATOM   639  O  O     . PHE A 1 83  ? 131.152 125.230 156.432 1.00 67.51  ? 83  PHE A O     1 
ATOM   640  C  CB    . PHE A 1 83  ? 132.124 122.787 157.392 1.00 56.97  ? 83  PHE A CB    1 
ATOM   641  C  CG    . PHE A 1 83  ? 131.950 121.594 158.288 1.00 55.95  ? 83  PHE A CG    1 
ATOM   642  C  CD1   . PHE A 1 83  ? 130.715 121.295 158.836 1.00 54.54  ? 83  PHE A CD1   1 
ATOM   643  C  CD2   . PHE A 1 83  ? 133.021 120.772 158.582 1.00 61.97  ? 83  PHE A CD2   1 
ATOM   644  C  CE1   . PHE A 1 83  ? 130.554 120.201 159.657 1.00 61.47  ? 83  PHE A CE1   1 
ATOM   645  C  CE2   . PHE A 1 83  ? 132.864 119.675 159.404 1.00 63.96  ? 83  PHE A CE2   1 
ATOM   646  C  CZ    . PHE A 1 83  ? 131.628 119.390 159.942 1.00 66.28  ? 83  PHE A CZ    1 
ATOM   647  N  N     . ARG A 1 84  ? 132.525 126.455 157.722 1.00 66.90  ? 84  ARG A N     1 
ATOM   648  C  CA    . ARG A 1 84  ? 132.150 127.706 157.083 1.00 68.65  ? 84  ARG A CA    1 
ATOM   649  C  C     . ARG A 1 84  ? 132.645 127.745 155.643 1.00 76.11  ? 84  ARG A C     1 
ATOM   650  O  O     . ARG A 1 84  ? 133.683 127.171 155.304 1.00 82.71  ? 84  ARG A O     1 
ATOM   651  C  CB    . ARG A 1 84  ? 132.722 128.890 157.859 1.00 74.04  ? 84  ARG A CB    1 
ATOM   652  C  CG    . ARG A 1 84  ? 134.224 128.810 158.074 1.00 75.35  ? 84  ARG A CG    1 
ATOM   653  C  CD    . ARG A 1 84  ? 134.690 129.806 159.116 1.00 80.66  ? 84  ARG A CD    1 
ATOM   654  N  NE    . ARG A 1 84  ? 134.466 129.322 160.473 1.00 85.13  ? 84  ARG A NE    1 
ATOM   655  C  CZ    . ARG A 1 84  ? 133.433 129.663 161.231 1.00 81.67  ? 84  ARG A CZ    1 
ATOM   656  N  NH1   . ARG A 1 84  ? 132.495 130.486 160.792 1.00 72.78  ? 84  ARG A NH1   1 
ATOM   657  N  NH2   . ARG A 1 84  ? 133.339 129.165 162.461 1.00 78.25  ? 84  ARG A NH2   1 
ATOM   658  N  N     . ASP A 1 85  ? 131.863 128.408 154.786 1.00 79.86  ? 85  ASP A N     1 
ATOM   659  C  CA    . ASP A 1 85  ? 132.229 128.697 153.400 1.00 88.80  ? 85  ASP A CA    1 
ATOM   660  C  C     . ASP A 1 85  ? 132.316 127.374 152.636 1.00 84.26  ? 85  ASP A C     1 
ATOM   661  O  O     . ASP A 1 85  ? 132.644 127.337 151.448 1.00 87.75  ? 85  ASP A O     1 
ATOM   662  C  CB    . ASP A 1 85  ? 133.551 129.487 153.370 1.00 93.29  ? 85  ASP A CB    1 
ATOM   663  C  CG    . ASP A 1 85  ? 133.976 129.930 151.970 1.00 99.71  ? 85  ASP A CG    1 
ATOM   664  O  OD1   . ASP A 1 85  ? 135.023 130.601 151.867 1.00 100.91 ? 85  ASP A OD1   1 
ATOM   665  O  OD2   . ASP A 1 85  ? 133.237 129.717 150.988 1.00 102.94 ? 85  ASP A OD2   1 
ATOM   666  N  N     . ASP A 1 86  ? 131.993 126.273 153.309 1.00 77.29  ? 86  ASP A N     1 
ATOM   667  C  CA    . ASP A 1 86  ? 132.144 124.949 152.731 1.00 73.22  ? 86  ASP A CA    1 
ATOM   668  C  C     . ASP A 1 86  ? 130.928 124.059 152.926 1.00 71.06  ? 86  ASP A C     1 
ATOM   669  O  O     . ASP A 1 86  ? 130.829 123.028 152.252 1.00 67.33  ? 86  ASP A O     1 
ATOM   670  C  CB    . ASP A 1 86  ? 133.373 124.249 153.331 1.00 69.91  ? 86  ASP A CB    1 
ATOM   671  C  CG    . ASP A 1 86  ? 133.965 123.221 152.405 1.00 81.31  ? 86  ASP A CG    1 
ATOM   672  O  OD1   . ASP A 1 86  ? 133.427 123.039 151.295 1.00 89.77  ? 86  ASP A OD1   1 
ATOM   673  O  OD2   . ASP A 1 86  ? 134.971 122.591 152.788 1.00 82.59  ? 86  ASP A OD2   1 
ATOM   674  N  N     . PHE A 1 87  ? 130.003 124.420 153.810 1.00 68.64  ? 87  PHE A N     1 
ATOM   675  C  CA    . PHE A 1 87  ? 128.838 123.589 154.072 1.00 56.59  ? 87  PHE A CA    1 
ATOM   676  C  C     . PHE A 1 87  ? 127.825 123.733 152.947 1.00 62.87  ? 87  PHE A C     1 
ATOM   677  O  O     . PHE A 1 87  ? 127.446 124.850 152.579 1.00 67.98  ? 87  PHE A O     1 
ATOM   678  C  CB    . PHE A 1 87  ? 128.198 123.972 155.404 1.00 48.92  ? 87  PHE A CB    1 
ATOM   679  C  CG    . PHE A 1 87  ? 126.972 123.176 155.732 1.00 45.61  ? 87  PHE A CG    1 
ATOM   680  C  CD1   . PHE A 1 87  ? 127.085 121.934 156.322 1.00 45.06  ? 87  PHE A CD1   1 
ATOM   681  C  CD2   . PHE A 1 87  ? 125.710 123.664 155.451 1.00 52.68  ? 87  PHE A CD2   1 
ATOM   682  C  CE1   . PHE A 1 87  ? 125.968 121.194 156.626 1.00 41.85  ? 87  PHE A CE1   1 
ATOM   683  C  CE2   . PHE A 1 87  ? 124.587 122.924 155.754 1.00 53.78  ? 87  PHE A CE2   1 
ATOM   684  C  CZ    . PHE A 1 87  ? 124.718 121.687 156.343 1.00 42.29  ? 87  PHE A CZ    1 
ATOM   685  N  N     . ARG A 1 88  ? 127.381 122.601 152.408 1.00 62.84  ? 88  ARG A N     1 
ATOM   686  C  CA    . ARG A 1 88  ? 126.329 122.595 151.396 1.00 60.69  ? 88  ARG A CA    1 
ATOM   687  C  C     . ARG A 1 88  ? 125.724 121.204 151.356 1.00 60.30  ? 88  ARG A C     1 
ATOM   688  O  O     . ARG A 1 88  ? 126.444 120.224 151.143 1.00 62.75  ? 88  ARG A O     1 
ATOM   689  C  CB    . ARG A 1 88  ? 126.869 122.983 150.023 1.00 61.13  ? 88  ARG A CB    1 
ATOM   690  C  CG    . ARG A 1 88  ? 125.784 123.084 148.964 1.00 71.89  ? 88  ARG A CG    1 
ATOM   691  C  CD    . ARG A 1 88  ? 126.303 122.737 147.581 1.00 80.32  ? 88  ARG A CD    1 
ATOM   692  N  NE    . ARG A 1 88  ? 125.271 122.100 146.773 1.00 81.59  ? 88  ARG A NE    1 
ATOM   693  C  CZ    . ARG A 1 88  ? 125.137 120.789 146.635 1.00 79.93  ? 88  ARG A CZ    1 
ATOM   694  N  NH1   . ARG A 1 88  ? 125.966 119.945 147.224 1.00 76.84  ? 88  ARG A NH1   1 
ATOM   695  N  NH2   . ARG A 1 88  ? 124.144 120.314 145.889 1.00 80.26  ? 88  ARG A NH2   1 
ATOM   696  N  N     . VAL A 1 89  ? 124.415 121.117 151.564 1.00 60.28  ? 89  VAL A N     1 
ATOM   697  C  CA    . VAL A 1 89  ? 123.680 119.863 151.476 1.00 59.26  ? 89  VAL A CA    1 
ATOM   698  C  C     . VAL A 1 89  ? 122.569 120.034 150.451 1.00 60.59  ? 89  VAL A C     1 
ATOM   699  O  O     . VAL A 1 89  ? 121.857 121.044 150.452 1.00 64.64  ? 89  VAL A O     1 
ATOM   700  C  CB    . VAL A 1 89  ? 123.128 119.422 152.848 1.00 51.50  ? 89  VAL A CB    1 
ATOM   701  C  CG1   . VAL A 1 89  ? 124.270 119.218 153.820 1.00 52.80  ? 89  VAL A CG1   1 
ATOM   702  C  CG2   . VAL A 1 89  ? 122.167 120.448 153.404 1.00 44.51  ? 89  VAL A CG2   1 
ATOM   703  N  N     . ASP A 1 90  ? 122.451 119.064 149.552 1.00 59.67  ? 90  ASP A N     1 
ATOM   704  C  CA    . ASP A 1 90  ? 121.496 119.170 148.462 1.00 62.18  ? 90  ASP A CA    1 
ATOM   705  C  C     . ASP A 1 90  ? 120.070 119.108 148.992 1.00 58.59  ? 90  ASP A C     1 
ATOM   706  O  O     . ASP A 1 90  ? 119.777 118.416 149.970 1.00 56.24  ? 90  ASP A O     1 
ATOM   707  C  CB    . ASP A 1 90  ? 121.725 118.057 147.443 1.00 66.25  ? 90  ASP A CB    1 
ATOM   708  C  CG    . ASP A 1 90  ? 121.297 118.451 146.045 1.00 73.21  ? 90  ASP A CG    1 
ATOM   709  O  OD1   . ASP A 1 90  ? 120.078 118.477 145.780 1.00 72.40  ? 90  ASP A OD1   1 
ATOM   710  O  OD2   . ASP A 1 90  ? 122.180 118.734 145.210 1.00 75.62  ? 90  ASP A OD2   1 
ATOM   711  N  N     . SER A 1 91  ? 119.177 119.847 148.328 1.00 56.14  ? 91  SER A N     1 
ATOM   712  C  CA    . SER A 1 91  ? 117.786 119.911 148.761 1.00 56.58  ? 91  SER A CA    1 
ATOM   713  C  C     . SER A 1 91  ? 117.114 118.546 148.754 1.00 56.71  ? 91  SER A C     1 
ATOM   714  O  O     . SER A 1 91  ? 116.121 118.351 149.465 1.00 54.33  ? 91  SER A O     1 
ATOM   715  C  CB    . SER A 1 91  ? 117.009 120.883 147.875 1.00 60.58  ? 91  SER A CB    1 
ATOM   716  O  OG    . SER A 1 91  ? 115.717 121.127 148.401 1.00 66.70  ? 91  SER A OG    1 
ATOM   717  N  N     . ASN A 1 92  ? 117.636 117.594 147.978 1.00 52.34  ? 92  ASN A N     1 
ATOM   718  C  CA    . ASN A 1 92  ? 117.101 116.241 147.979 1.00 48.07  ? 92  ASN A CA    1 
ATOM   719  C  C     . ASN A 1 92  ? 117.430 115.483 149.258 1.00 47.32  ? 92  ASN A C     1 
ATOM   720  O  O     . ASN A 1 92  ? 116.858 114.412 149.486 1.00 47.59  ? 92  ASN A O     1 
ATOM   721  C  CB    . ASN A 1 92  ? 117.626 115.476 146.765 1.00 45.10  ? 92  ASN A CB    1 
ATOM   722  C  CG    . ASN A 1 92  ? 116.946 115.893 145.477 1.00 46.53  ? 92  ASN A CG    1 
ATOM   723  O  OD1   . ASN A 1 92  ? 115.721 115.928 145.394 1.00 51.25  ? 92  ASN A OD1   1 
ATOM   724  N  ND2   . ASN A 1 92  ? 117.741 116.213 144.464 1.00 45.84  ? 92  ASN A ND2   1 
ATOM   725  N  N     . ALA A 1 93  ? 118.334 116.003 150.086 1.00 43.30  ? 93  ALA A N     1 
ATOM   726  C  CA    . ALA A 1 93  ? 118.560 115.466 151.421 1.00 43.09  ? 93  ALA A CA    1 
ATOM   727  C  C     . ALA A 1 93  ? 117.701 116.169 152.460 1.00 49.55  ? 93  ALA A C     1 
ATOM   728  O  O     . ALA A 1 93  ? 117.186 115.525 153.382 1.00 52.19  ? 93  ALA A O     1 
ATOM   729  C  CB    . ALA A 1 93  ? 120.035 115.592 151.803 1.00 45.90  ? 93  ALA A CB    1 
ATOM   730  N  N     . LYS A 1 94  ? 117.543 117.487 152.318 1.00 51.99  ? 94  LYS A N     1 
ATOM   731  C  CA    . LYS A 1 94  ? 116.655 118.232 153.200 1.00 45.50  ? 94  LYS A CA    1 
ATOM   732  C  C     . LYS A 1 94  ? 115.223 117.733 153.084 1.00 46.81  ? 94  LYS A C     1 
ATOM   733  O  O     . LYS A 1 94  ? 114.499 117.675 154.081 1.00 48.38  ? 94  LYS A O     1 
ATOM   734  C  CB    . LYS A 1 94  ? 116.723 119.723 152.882 1.00 42.69  ? 94  LYS A CB    1 
ATOM   735  C  CG    . LYS A 1 94  ? 117.934 120.432 153.446 1.00 49.63  ? 94  LYS A CG    1 
ATOM   736  C  CD    . LYS A 1 94  ? 118.132 121.773 152.768 1.00 49.86  ? 94  LYS A CD    1 
ATOM   737  C  CE    . LYS A 1 94  ? 119.272 122.548 153.394 1.00 46.34  ? 94  LYS A CE    1 
ATOM   738  N  NZ    . LYS A 1 94  ? 119.772 123.614 152.486 1.00 50.63  ? 94  LYS A NZ    1 
ATOM   739  N  N     . ALA A 1 95  ? 114.796 117.364 151.875 1.00 49.87  ? 95  ALA A N     1 
ATOM   740  C  CA    . ALA A 1 95  ? 113.443 116.846 151.696 1.00 50.70  ? 95  ALA A CA    1 
ATOM   741  C  C     . ALA A 1 95  ? 113.238 115.550 152.475 1.00 47.77  ? 95  ALA A C     1 
ATOM   742  O  O     . ALA A 1 95  ? 112.266 115.410 153.229 1.00 46.70  ? 95  ALA A O     1 
ATOM   743  C  CB    . ALA A 1 95  ? 113.160 116.636 150.210 1.00 42.20  ? 95  ALA A CB    1 
ATOM   744  N  N     . LYS A 1 96  ? 114.149 114.591 152.302 1.00 41.92  ? 96  LYS A N     1 
ATOM   745  C  CA    . LYS A 1 96  ? 114.042 113.316 153.005 1.00 40.92  ? 96  LYS A CA    1 
ATOM   746  C  C     . LYS A 1 96  ? 114.076 113.519 154.512 1.00 47.16  ? 96  LYS A C     1 
ATOM   747  O  O     . LYS A 1 96  ? 113.276 112.932 155.255 1.00 48.43  ? 96  LYS A O     1 
ATOM   748  C  CB    . LYS A 1 96  ? 115.177 112.391 152.570 1.00 39.90  ? 96  LYS A CB    1 
ATOM   749  C  CG    . LYS A 1 96  ? 115.043 110.962 153.055 1.00 39.73  ? 96  LYS A CG    1 
ATOM   750  C  CD    . LYS A 1 96  ? 115.978 110.667 154.205 1.00 40.63  ? 96  LYS A CD    1 
ATOM   751  C  CE    . LYS A 1 96  ? 115.772 109.251 154.704 1.00 48.85  ? 96  LYS A CE    1 
ATOM   752  N  NZ    . LYS A 1 96  ? 116.036 109.122 156.160 1.00 54.07  ? 96  LYS A NZ    1 
ATOM   753  N  N     . VAL A 1 97  ? 115.003 114.354 154.980 1.00 48.81  ? 97  VAL A N     1 
ATOM   754  C  CA    . VAL A 1 97  ? 115.136 114.599 156.410 1.00 42.85  ? 97  VAL A CA    1 
ATOM   755  C  C     . VAL A 1 97  ? 113.880 115.254 156.966 1.00 48.43  ? 97  VAL A C     1 
ATOM   756  O  O     . VAL A 1 97  ? 113.403 114.889 158.046 1.00 52.27  ? 97  VAL A O     1 
ATOM   757  C  CB    . VAL A 1 97  ? 116.391 115.445 156.676 1.00 40.04  ? 97  VAL A CB    1 
ATOM   758  C  CG1   . VAL A 1 97  ? 116.213 116.243 157.923 1.00 45.36  ? 97  VAL A CG1   1 
ATOM   759  C  CG2   . VAL A 1 97  ? 117.605 114.546 156.794 1.00 41.04  ? 97  VAL A CG2   1 
ATOM   760  N  N     . ALA A 1 98  ? 113.320 116.226 156.241 1.00 46.42  ? 98  ALA A N     1 
ATOM   761  C  CA    . ALA A 1 98  ? 112.117 116.902 156.710 1.00 43.02  ? 98  ALA A CA    1 
ATOM   762  C  C     . ALA A 1 98  ? 110.932 115.951 156.761 1.00 44.22  ? 98  ALA A C     1 
ATOM   763  O  O     . ALA A 1 98  ? 110.126 116.006 157.694 1.00 52.19  ? 98  ALA A O     1 
ATOM   764  C  CB    . ALA A 1 98  ? 111.809 118.101 155.816 1.00 47.11  ? 98  ALA A CB    1 
ATOM   765  N  N     . GLY A 1 99  ? 110.808 115.068 155.770 1.00 38.72  ? 99  GLY A N     1 
ATOM   766  C  CA    . GLY A 1 99  ? 109.733 114.090 155.811 1.00 42.42  ? 99  GLY A CA    1 
ATOM   767  C  C     . GLY A 1 99  ? 109.858 113.135 156.983 1.00 45.66  ? 99  GLY A C     1 
ATOM   768  O  O     . GLY A 1 99  ? 108.875 112.850 157.678 1.00 50.04  ? 99  GLY A O     1 
ATOM   769  N  N     . ASP A 1 100 ? 111.073 112.641 157.230 1.00 43.08  ? 100 ASP A N     1 
ATOM   770  C  CA    . ASP A 1 100 ? 111.279 111.744 158.363 1.00 44.53  ? 100 ASP A CA    1 
ATOM   771  C  C     . ASP A 1 100 ? 111.024 112.454 159.688 1.00 48.22  ? 100 ASP A C     1 
ATOM   772  O  O     . ASP A 1 100 ? 110.455 111.867 160.615 1.00 52.69  ? 100 ASP A O     1 
ATOM   773  C  CB    . ASP A 1 100 ? 112.691 111.171 158.323 1.00 47.16  ? 100 ASP A CB    1 
ATOM   774  C  CG    . ASP A 1 100 ? 112.748 109.814 157.655 1.00 61.37  ? 100 ASP A CG    1 
ATOM   775  O  OD1   . ASP A 1 100 ? 111.679 109.193 157.474 1.00 62.68  ? 100 ASP A OD1   1 
ATOM   776  O  OD2   . ASP A 1 100 ? 113.862 109.366 157.313 1.00 71.22  ? 100 ASP A OD2   1 
ATOM   777  N  N     . ILE A 1 101 ? 111.442 113.717 159.797 1.00 47.94  ? 101 ILE A N     1 
ATOM   778  C  CA    . ILE A 1 101 ? 111.200 114.485 161.014 1.00 43.07  ? 101 ILE A CA    1 
ATOM   779  C  C     . ILE A 1 101 ? 109.710 114.693 161.223 1.00 42.02  ? 101 ILE A C     1 
ATOM   780  O  O     . ILE A 1 101 ? 109.209 114.582 162.345 1.00 47.68  ? 101 ILE A O     1 
ATOM   781  C  CB    . ILE A 1 101 ? 111.957 115.823 160.961 1.00 41.57  ? 101 ILE A CB    1 
ATOM   782  C  CG1   . ILE A 1 101 ? 113.439 115.599 161.228 1.00 37.89  ? 101 ILE A CG1   1 
ATOM   783  C  CG2   . ILE A 1 101 ? 111.391 116.805 161.968 1.00 39.01  ? 101 ILE A CG2   1 
ATOM   784  C  CD1   . ILE A 1 101 ? 114.261 116.806 160.951 1.00 45.16  ? 101 ILE A CD1   1 
ATOM   785  N  N     . PHE A 1 102 ? 108.980 115.012 160.153 1.00 40.99  ? 102 PHE A N     1 
ATOM   786  C  CA    . PHE A 1 102 ? 107.531 115.140 160.258 1.00 47.89  ? 102 PHE A CA    1 
ATOM   787  C  C     . PHE A 1 102 ? 106.914 113.855 160.789 1.00 49.72  ? 102 PHE A C     1 
ATOM   788  O  O     . PHE A 1 102 ? 106.117 113.876 161.738 1.00 54.64  ? 102 PHE A O     1 
ATOM   789  C  CB    . PHE A 1 102 ? 106.941 115.497 158.894 1.00 47.23  ? 102 PHE A CB    1 
ATOM   790  C  CG    . PHE A 1 102 ? 105.441 115.566 158.877 1.00 46.64  ? 102 PHE A CG    1 
ATOM   791  C  CD1   . PHE A 1 102 ? 104.748 116.188 159.897 1.00 49.20  ? 102 PHE A CD1   1 
ATOM   792  C  CD2   . PHE A 1 102 ? 104.726 115.015 157.831 1.00 51.79  ? 102 PHE A CD2   1 
ATOM   793  C  CE1   . PHE A 1 102 ? 103.371 116.251 159.878 1.00 53.34  ? 102 PHE A CE1   1 
ATOM   794  C  CE2   . PHE A 1 102 ? 103.350 115.078 157.807 1.00 58.54  ? 102 PHE A CE2   1 
ATOM   795  C  CZ    . PHE A 1 102 ? 102.671 115.697 158.831 1.00 56.31  ? 102 PHE A CZ    1 
ATOM   796  N  N     . GLU A 1 103 ? 107.302 112.719 160.205 1.00 50.93  ? 103 GLU A N     1 
ATOM   797  C  CA    . GLU A 1 103 ? 106.762 111.438 160.648 1.00 53.95  ? 103 GLU A CA    1 
ATOM   798  C  C     . GLU A 1 103 ? 107.043 111.199 162.126 1.00 48.28  ? 103 GLU A C     1 
ATOM   799  O  O     . GLU A 1 103 ? 106.128 110.902 162.904 1.00 52.44  ? 103 GLU A O     1 
ATOM   800  C  CB    . GLU A 1 103 ? 107.341 110.306 159.801 1.00 53.75  ? 103 GLU A CB    1 
ATOM   801  C  CG    . GLU A 1 103 ? 106.380 109.161 159.581 1.00 54.07  ? 103 GLU A CG    1 
ATOM   802  C  CD    . GLU A 1 103 ? 106.210 108.313 160.822 1.00 62.06  ? 103 GLU A CD    1 
ATOM   803  O  OE1   . GLU A 1 103 ? 107.199 108.143 161.564 1.00 71.91  ? 103 GLU A OE1   1 
ATOM   804  O  OE2   . GLU A 1 103 ? 105.087 107.831 161.066 1.00 56.26  ? 103 GLU A OE2   1 
ATOM   805  N  N     . ILE A 1 104 ? 108.301 111.351 162.540 1.00 43.75  ? 104 ILE A N     1 
ATOM   806  C  CA    . ILE A 1 104 ? 108.675 110.990 163.904 1.00 45.46  ? 104 ILE A CA    1 
ATOM   807  C  C     . ILE A 1 104 ? 108.070 111.960 164.914 1.00 46.35  ? 104 ILE A C     1 
ATOM   808  O  O     . ILE A 1 104 ? 107.608 111.548 165.983 1.00 51.33  ? 104 ILE A O     1 
ATOM   809  C  CB    . ILE A 1 104 ? 110.206 110.904 164.037 1.00 45.37  ? 104 ILE A CB    1 
ATOM   810  C  CG1   . ILE A 1 104 ? 110.755 109.839 163.088 1.00 49.60  ? 104 ILE A CG1   1 
ATOM   811  C  CG2   . ILE A 1 104 ? 110.594 110.585 165.466 1.00 41.45  ? 104 ILE A CG2   1 
ATOM   812  C  CD1   . ILE A 1 104 ? 112.203 109.488 163.325 1.00 52.10  ? 104 ILE A CD1   1 
ATOM   813  N  N     . VAL A 1 105 ? 108.056 113.256 164.600 1.00 47.06  ? 105 VAL A N     1 
ATOM   814  C  CA    . VAL A 1 105 ? 107.501 114.240 165.524 1.00 44.40  ? 105 VAL A CA    1 
ATOM   815  C  C     . VAL A 1 105 ? 105.999 114.045 165.685 1.00 47.98  ? 105 VAL A C     1 
ATOM   816  O  O     . VAL A 1 105 ? 105.475 114.098 166.804 1.00 55.39  ? 105 VAL A O     1 
ATOM   817  C  CB    . VAL A 1 105 ? 107.837 115.666 165.056 1.00 41.83  ? 105 VAL A CB    1 
ATOM   818  C  CG1   . VAL A 1 105 ? 107.018 116.679 165.828 1.00 42.68  ? 105 VAL A CG1   1 
ATOM   819  C  CG2   . VAL A 1 105 ? 109.316 115.943 165.230 1.00 39.38  ? 105 VAL A CG2   1 
ATOM   820  N  N     . SER A 1 106 ? 105.276 113.823 164.582 1.00 45.97  ? 106 SER A N     1 
ATOM   821  C  CA    . SER A 1 106 ? 103.843 113.581 164.702 1.00 47.52  ? 106 SER A CA    1 
ATOM   822  C  C     . SER A 1 106 ? 103.567 112.288 165.459 1.00 54.26  ? 106 SER A C     1 
ATOM   823  O  O     . SER A 1 106 ? 102.619 112.212 166.253 1.00 59.26  ? 106 SER A O     1 
ATOM   824  C  CB    . SER A 1 106 ? 103.198 113.548 163.320 1.00 49.69  ? 106 SER A CB    1 
ATOM   825  O  OG    . SER A 1 106 ? 103.316 114.805 162.681 1.00 59.74  ? 106 SER A OG    1 
ATOM   826  N  N     . SER A 1 107 ? 104.394 111.262 165.237 1.00 54.58  ? 107 SER A N     1 
ATOM   827  C  CA    . SER A 1 107 ? 104.233 110.019 165.980 1.00 50.07  ? 107 SER A CA    1 
ATOM   828  C  C     . SER A 1 107 ? 104.457 110.236 167.470 1.00 55.15  ? 107 SER A C     1 
ATOM   829  O  O     . SER A 1 107 ? 103.741 109.668 168.297 1.00 58.58  ? 107 SER A O     1 
ATOM   830  C  CB    . SER A 1 107 ? 105.192 108.961 165.441 1.00 46.93  ? 107 SER A CB    1 
ATOM   831  O  OG    . SER A 1 107 ? 104.961 108.731 164.063 1.00 44.58  ? 107 SER A OG    1 
ATOM   832  N  N     . ALA A 1 108 ? 105.437 111.066 167.831 1.00 53.37  ? 108 ALA A N     1 
ATOM   833  C  CA    . ALA A 1 108 ? 105.678 111.357 169.242 1.00 50.59  ? 108 ALA A CA    1 
ATOM   834  C  C     . ALA A 1 108 ? 104.529 112.151 169.850 1.00 52.17  ? 108 ALA A C     1 
ATOM   835  O  O     . ALA A 1 108 ? 104.143 111.914 171.001 1.00 62.22  ? 108 ALA A O     1 
ATOM   836  C  CB    . ALA A 1 108 ? 106.993 112.113 169.405 1.00 51.67  ? 108 ALA A CB    1 
ATOM   837  N  N     . VAL A 1 109 ? 103.977 113.105 169.099 1.00 46.00  ? 109 VAL A N     1 
ATOM   838  C  CA    . VAL A 1 109 ? 102.851 113.888 169.602 1.00 48.85  ? 109 VAL A CA    1 
ATOM   839  C  C     . VAL A 1 109 ? 101.659 112.981 169.877 1.00 60.18  ? 109 VAL A C     1 
ATOM   840  O  O     . VAL A 1 109 ? 101.039 113.038 170.948 1.00 72.75  ? 109 VAL A O     1 
ATOM   841  C  CB    . VAL A 1 109 ? 102.485 115.005 168.611 1.00 44.83  ? 109 VAL A CB    1 
ATOM   842  C  CG1   . VAL A 1 109 ? 101.209 115.692 169.048 1.00 48.09  ? 109 VAL A CG1   1 
ATOM   843  C  CG2   . VAL A 1 109 ? 103.614 116.003 168.498 1.00 52.51  ? 109 VAL A CG2   1 
ATOM   844  N  N     . MET A 1 110 ? 101.330 112.111 168.921 1.00 57.35  ? 110 MET A N     1 
ATOM   845  C  CA    . MET A 1 110 ? 100.205 111.213 169.142 1.00 58.85  ? 110 MET A CA    1 
ATOM   846  C  C     . MET A 1 110 ? 100.521 110.133 170.171 1.00 62.92  ? 110 MET A C     1 
ATOM   847  O  O     . MET A 1 110 ? 99.600  109.632 170.819 1.00 72.60  ? 110 MET A O     1 
ATOM   848  C  CB    . MET A 1 110 ? 99.743  110.602 167.818 1.00 62.69  ? 110 MET A CB    1 
ATOM   849  C  CG    . MET A 1 110 ? 99.552  111.642 166.723 1.00 65.93  ? 110 MET A CG    1 
ATOM   850  S  SD    . MET A 1 110 ? 98.605  111.076 165.300 1.00 77.71  ? 110 MET A SD    1 
ATOM   851  C  CE    . MET A 1 110 ? 99.057  109.352 165.252 1.00 58.62  ? 110 MET A CE    1 
ATOM   852  N  N     . TRP A 1 111 ? 101.795 109.789 170.370 1.00 56.61  ? 111 TRP A N     1 
ATOM   853  C  CA    . TRP A 1 111 ? 102.154 108.902 171.472 1.00 59.91  ? 111 TRP A CA    1 
ATOM   854  C  C     . TRP A 1 111 ? 101.897 109.563 172.818 1.00 62.84  ? 111 TRP A C     1 
ATOM   855  O  O     . TRP A 1 111 ? 101.414 108.914 173.750 1.00 71.35  ? 111 TRP A O     1 
ATOM   856  C  CB    . TRP A 1 111 ? 103.617 108.476 171.356 1.00 61.76  ? 111 TRP A CB    1 
ATOM   857  C  CG    . TRP A 1 111 ? 104.134 107.720 172.551 1.00 64.76  ? 111 TRP A CG    1 
ATOM   858  C  CD1   . TRP A 1 111 ? 104.540 108.246 173.744 1.00 62.98  ? 111 TRP A CD1   1 
ATOM   859  C  CD2   . TRP A 1 111 ? 104.294 106.301 172.667 1.00 70.81  ? 111 TRP A CD2   1 
ATOM   860  N  NE1   . TRP A 1 111 ? 104.943 107.245 174.591 1.00 67.26  ? 111 TRP A NE1   1 
ATOM   861  C  CE2   . TRP A 1 111 ? 104.803 106.041 173.954 1.00 71.19  ? 111 TRP A CE2   1 
ATOM   862  C  CE3   . TRP A 1 111 ? 104.060 105.226 171.806 1.00 75.47  ? 111 TRP A CE3   1 
ATOM   863  C  CZ2   . TRP A 1 111 ? 105.080 104.752 174.400 1.00 78.03  ? 111 TRP A CZ2   1 
ATOM   864  C  CZ3   . TRP A 1 111 ? 104.336 103.947 172.252 1.00 78.33  ? 111 TRP A CZ3   1 
ATOM   865  C  CH2   . TRP A 1 111 ? 104.840 103.721 173.536 1.00 79.15  ? 111 TRP A CH2   1 
ATOM   866  N  N     . ASN A 1 112 ? 102.235 110.846 172.947 1.00 59.61  ? 112 ASN A N     1 
ATOM   867  C  CA    . ASN A 1 112 ? 101.919 111.561 174.180 1.00 62.51  ? 112 ASN A CA    1 
ATOM   868  C  C     . ASN A 1 112 ? 100.412 111.638 174.392 1.00 68.79  ? 112 ASN A C     1 
ATOM   869  O  O     . ASN A 1 112 ? 99.923  111.481 175.520 1.00 79.93  ? 112 ASN A O     1 
ATOM   870  C  CB    . ASN A 1 112 ? 102.533 112.960 174.157 1.00 62.03  ? 112 ASN A CB    1 
ATOM   871  C  CG    . ASN A 1 112 ? 103.889 113.009 174.826 1.00 67.82  ? 112 ASN A CG    1 
ATOM   872  O  OD1   . ASN A 1 112 ? 104.215 112.161 175.653 1.00 77.18  ? 112 ASN A OD1   1 
ATOM   873  N  ND2   . ASN A 1 112 ? 104.686 114.009 174.478 1.00 62.05  ? 112 ASN A ND2   1 
ATOM   874  N  N     . CYS A 1 113 ? 99.659  111.873 173.314 1.00 67.23  ? 113 CYS A N     1 
ATOM   875  C  CA    . CYS A 1 113 ? 98.202  111.870 173.422 1.00 72.65  ? 113 CYS A CA    1 
ATOM   876  C  C     . CYS A 1 113 ? 97.686  110.514 173.890 1.00 76.18  ? 113 CYS A C     1 
ATOM   877  O  O     . CYS A 1 113 ? 96.794  110.439 174.744 1.00 75.20  ? 113 CYS A O     1 
ATOM   878  C  CB    . CYS A 1 113 ? 97.574  112.239 172.081 1.00 70.68  ? 113 CYS A CB    1 
ATOM   879  S  SG    . CYS A 1 113 ? 98.081  113.833 171.426 1.00 80.93  ? 113 CYS A SG    1 
ATOM   880  N  N     . ALA A 1 114 ? 98.237  109.431 173.338 1.00 74.99  ? 114 ALA A N     1 
ATOM   881  C  CA    . ALA A 1 114 ? 97.827  108.090 173.739 1.00 72.68  ? 114 ALA A CA    1 
ATOM   882  C  C     . ALA A 1 114 ? 98.179  107.816 175.194 1.00 80.50  ? 114 ALA A C     1 
ATOM   883  O  O     . ALA A 1 114 ? 97.412  107.168 175.912 1.00 92.03  ? 114 ALA A O     1 
ATOM   884  C  CB    . ALA A 1 114 ? 98.475  107.051 172.829 1.00 68.85  ? 114 ALA A CB    1 
ATOM   885  N  N     . ALA A 1 115 ? 99.346  108.282 175.640 1.00 75.41  ? 115 ALA A N     1 
ATOM   886  C  CA    . ALA A 1 115 ? 99.728  108.101 177.036 1.00 77.91  ? 115 ALA A CA    1 
ATOM   887  C  C     . ALA A 1 115 ? 98.767  108.827 177.967 1.00 81.23  ? 115 ALA A C     1 
ATOM   888  O  O     . ALA A 1 115 ? 98.357  108.281 178.998 1.00 86.12  ? 115 ALA A O     1 
ATOM   889  C  CB    . ALA A 1 115 ? 101.160 108.587 177.257 1.00 80.67  ? 115 ALA A CB    1 
ATOM   890  N  N     . ARG A 1 116 ? 98.388  110.058 177.614 1.00 78.31  ? 116 ARG A N     1 
ATOM   891  C  CA    . ARG A 1 116 ? 97.419  110.787 178.429 1.00 77.74  ? 116 ARG A CA    1 
ATOM   892  C  C     . ARG A 1 116 ? 96.063  110.090 178.435 1.00 83.60  ? 116 ARG A C     1 
ATOM   893  O  O     . ARG A 1 116 ? 95.397  110.011 179.476 1.00 89.44  ? 116 ARG A O     1 
ATOM   894  C  CB    . ARG A 1 116 ? 97.281  112.220 177.924 1.00 81.31  ? 116 ARG A CB    1 
ATOM   895  C  CG    . ARG A 1 116 ? 96.383  113.083 178.780 1.00 89.97  ? 116 ARG A CG    1 
ATOM   896  C  CD    . ARG A 1 116 ? 96.556  114.549 178.443 1.00 93.95  ? 116 ARG A CD    1 
ATOM   897  N  NE    . ARG A 1 116 ? 97.930  114.992 178.637 1.00 86.84  ? 116 ARG A NE    1 
ATOM   898  C  CZ    . ARG A 1 116 ? 98.311  116.261 178.634 1.00 82.89  ? 116 ARG A CZ    1 
ATOM   899  N  NH1   . ARG A 1 116 ? 97.442  117.241 178.448 1.00 84.36  ? 116 ARG A NH1   1 
ATOM   900  N  NH2   . ARG A 1 116 ? 99.594  116.554 178.826 1.00 81.57  ? 116 ARG A NH2   1 
ATOM   901  N  N     . TRP A 1 117 ? 95.637  109.581 177.277 1.00 81.82  ? 117 TRP A N     1 
ATOM   902  C  CA    . TRP A 1 117 ? 94.365  108.868 177.192 1.00 80.62  ? 117 TRP A CA    1 
ATOM   903  C  C     . TRP A 1 117 ? 94.377  107.609 178.051 1.00 84.08  ? 117 TRP A C     1 
ATOM   904  O  O     . TRP A 1 117 ? 93.403  107.316 178.755 1.00 88.82  ? 117 TRP A O     1 
ATOM   905  C  CB    . TRP A 1 117 ? 94.077  108.532 175.731 1.00 80.63  ? 117 TRP A CB    1 
ATOM   906  C  CG    . TRP A 1 117 ? 92.850  107.723 175.483 1.00 83.42  ? 117 TRP A CG    1 
ATOM   907  C  CD1   . TRP A 1 117 ? 92.755  106.364 175.454 1.00 87.12  ? 117 TRP A CD1   1 
ATOM   908  C  CD2   . TRP A 1 117 ? 91.542  108.222 175.184 1.00 88.04  ? 117 TRP A CD2   1 
ATOM   909  N  NE1   . TRP A 1 117 ? 91.466  105.985 175.174 1.00 92.15  ? 117 TRP A NE1   1 
ATOM   910  C  CE2   . TRP A 1 117 ? 90.702  107.109 175.003 1.00 93.37  ? 117 TRP A CE2   1 
ATOM   911  C  CE3   . TRP A 1 117 ? 90.999  109.504 175.061 1.00 87.85  ? 117 TRP A CE3   1 
ATOM   912  C  CZ2   . TRP A 1 117 ? 89.349  107.237 174.701 1.00 96.95  ? 117 TRP A CZ2   1 
ATOM   913  C  CZ3   . TRP A 1 117 ? 89.656  109.629 174.765 1.00 91.80  ? 117 TRP A CZ3   1 
ATOM   914  C  CH2   . TRP A 1 117 ? 88.845  108.502 174.591 1.00 95.85  ? 117 TRP A CH2   1 
ATOM   915  N  N     . ASN A 1 118 ? 95.476  106.852 178.008 1.00 84.05  ? 118 ASN A N     1 
ATOM   916  C  CA    . ASN A 1 118 ? 95.593  105.657 178.838 1.00 86.13  ? 118 ASN A CA    1 
ATOM   917  C  C     . ASN A 1 118 ? 95.609  106.013 180.318 1.00 91.06  ? 118 ASN A C     1 
ATOM   918  O  O     . ASN A 1 118 ? 95.018  105.303 181.141 1.00 98.66  ? 118 ASN A O     1 
ATOM   919  C  CB    . ASN A 1 118 ? 96.852  104.875 178.463 1.00 80.65  ? 118 ASN A CB    1 
ATOM   920  C  CG    . ASN A 1 118 ? 96.849  104.419 177.020 1.00 82.52  ? 118 ASN A CG    1 
ATOM   921  O  OD1   . ASN A 1 118 ? 95.801  104.344 176.382 1.00 84.06  ? 118 ASN A OD1   1 
ATOM   922  N  ND2   . ASN A 1 118 ? 98.028  104.111 176.496 1.00 84.65  ? 118 ASN A ND2   1 
ATOM   923  N  N     . SER A 1 119 ? 96.291  107.103 180.679 1.00 88.69  ? 119 SER A N     1 
ATOM   924  C  CA    . SER A 1 119 ? 96.288  107.544 182.069 1.00 86.93  ? 119 SER A CA    1 
ATOM   925  C  C     . SER A 1 119 ? 94.881  107.897 182.526 1.00 88.07  ? 119 SER A C     1 
ATOM   926  O  O     . SER A 1 119 ? 94.490  107.584 183.657 1.00 95.24  ? 119 SER A O     1 
ATOM   927  C  CB    . SER A 1 119 ? 97.226  108.738 182.243 1.00 88.97  ? 119 SER A CB    1 
ATOM   928  O  OG    . SER A 1 119 ? 96.737  109.629 183.228 1.00 92.07  ? 119 SER A OG    1 
ATOM   929  N  N     . LEU A 1 120 ? 94.106  108.556 181.662 1.00 87.10  ? 120 LEU A N     1 
ATOM   930  C  CA    . LEU A 1 120 ? 92.719  108.857 182.004 1.00 93.09  ? 120 LEU A CA    1 
ATOM   931  C  C     . LEU A 1 120 ? 91.899  107.583 182.165 1.00 96.64  ? 120 LEU A C     1 
ATOM   932  O  O     . LEU A 1 120 ? 91.092  107.468 183.095 1.00 100.26 ? 120 LEU A O     1 
ATOM   933  C  CB    . LEU A 1 120 ? 92.094  109.759 180.941 1.00 95.50  ? 120 LEU A CB    1 
ATOM   934  C  CG    . LEU A 1 120 ? 90.572  109.898 181.011 1.00 91.09  ? 120 LEU A CG    1 
ATOM   935  C  CD1   . LEU A 1 120 ? 90.164  110.678 182.249 1.00 92.32  ? 120 LEU A CD1   1 
ATOM   936  C  CD2   . LEU A 1 120 ? 90.025  110.556 179.758 1.00 92.34  ? 120 LEU A CD2   1 
ATOM   937  N  N     . MET A 1 121 ? 92.088  106.615 181.265 1.00 96.71  ? 121 MET A N     1 
ATOM   938  C  CA    . MET A 1 121 ? 91.294  105.390 181.321 1.00 100.87 ? 121 MET A CA    1 
ATOM   939  C  C     . MET A 1 121 ? 91.615  104.555 182.556 1.00 102.12 ? 121 MET A C     1 
ATOM   940  O  O     . MET A 1 121 ? 90.708  103.988 183.176 1.00 105.09 ? 121 MET A O     1 
ATOM   941  C  CB    . MET A 1 121 ? 91.491  104.568 180.049 1.00 95.73  ? 121 MET A CB    1 
ATOM   942  C  CG    . MET A 1 121 ? 90.837  105.186 178.834 1.00 96.48  ? 121 MET A CG    1 
ATOM   943  S  SD    . MET A 1 121 ? 89.310  106.005 179.327 1.00 108.20 ? 121 MET A SD    1 
ATOM   944  C  CE    . MET A 1 121 ? 88.455  106.142 177.766 1.00 98.62  ? 121 MET A CE    1 
ATOM   945  N  N     . VAL A 1 122 ? 92.892  104.456 182.927 1.00 99.10  ? 122 VAL A N     1 
ATOM   946  C  CA    . VAL A 1 122 ? 93.255  103.611 184.061 1.00 98.73  ? 122 VAL A CA    1 
ATOM   947  C  C     . VAL A 1 122 ? 92.725  104.208 185.361 1.00 100.85 ? 122 VAL A C     1 
ATOM   948  O  O     . VAL A 1 122 ? 92.259  103.482 186.248 1.00 107.67 ? 122 VAL A O     1 
ATOM   949  C  CB    . VAL A 1 122 ? 94.779  103.392 184.101 1.00 99.85  ? 122 VAL A CB    1 
ATOM   950  C  CG1   . VAL A 1 122 ? 95.254  103.131 185.518 1.00 102.15 ? 122 VAL A CG1   1 
ATOM   951  C  CG2   . VAL A 1 122 ? 95.169  102.240 183.196 1.00 98.82  ? 122 VAL A CG2   1 
ATOM   952  N  N     . GLY A 1 123 ? 92.755  105.535 185.485 1.00 99.70  ? 123 GLY A N     1 
ATOM   953  C  CA    . GLY A 1 123 ? 92.182  106.180 186.651 1.00 96.92  ? 123 GLY A CA    1 
ATOM   954  C  C     . GLY A 1 123 ? 93.012  107.281 187.281 1.00 102.91 ? 123 GLY A C     1 
ATOM   955  O  O     . GLY A 1 123 ? 92.697  107.736 188.385 1.00 107.74 ? 123 GLY A O     1 
ATOM   956  N  N     . GLU A 1 124 ? 94.070  107.723 186.603 1.00 104.09 ? 124 GLU A N     1 
ATOM   957  C  CA    . GLU A 1 124 ? 94.914  108.802 187.106 1.00 102.70 ? 124 GLU A CA    1 
ATOM   958  C  C     . GLU A 1 124 ? 94.384  110.188 186.763 1.00 104.60 ? 124 GLU A C     1 
ATOM   959  O  O     . GLU A 1 124 ? 95.148  111.158 186.820 1.00 106.29 ? 124 GLU A O     1 
ATOM   960  C  CB    . GLU A 1 124 ? 96.342  108.649 186.576 1.00 99.17  ? 124 GLU A CB    1 
ATOM   961  C  CG    . GLU A 1 124 ? 97.214  107.700 187.382 1.00 99.93  ? 124 GLU A CG    1 
ATOM   962  C  CD    . GLU A 1 124 ? 96.983  106.247 187.030 1.00 107.82 ? 124 GLU A CD    1 
ATOM   963  O  OE1   . GLU A 1 124 ? 95.846  105.902 186.654 1.00 105.65 ? 124 GLU A OE1   1 
ATOM   964  O  OE2   . GLU A 1 124 ? 97.938  105.448 187.129 1.00 115.85 ? 124 GLU A OE2   1 
ATOM   965  N  N     . GLY A 1 125 ? 93.108  110.310 186.409 1.00 102.39 ? 125 GLY A N     1 
ATOM   966  C  CA    . GLY A 1 125 ? 92.576  111.620 186.103 1.00 103.17 ? 125 GLY A CA    1 
ATOM   967  C  C     . GLY A 1 125 ? 93.040  112.127 184.746 1.00 102.78 ? 125 GLY A C     1 
ATOM   968  O  O     . GLY A 1 125 ? 93.585  111.392 183.918 1.00 99.21  ? 125 GLY A O     1 
ATOM   969  N  N     . TRP A 1 126 ? 92.816  113.420 184.530 1.00 102.89 ? 126 TRP A N     1 
ATOM   970  C  CA    . TRP A 1 126 ? 93.130  114.083 183.268 1.00 96.75  ? 126 TRP A CA    1 
ATOM   971  C  C     . TRP A 1 126 ? 94.152  115.179 183.537 1.00 95.04  ? 126 TRP A C     1 
ATOM   972  C  CB    . TRP A 1 126 ? 91.867  114.655 182.629 1.00 102.92 ? 126 TRP A CB    1 
ATOM   973  C  CG    . TRP A 1 126 ? 92.086  115.249 181.277 1.00 106.02 ? 126 TRP A CG    1 
ATOM   974  C  CD1   . TRP A 1 126 ? 92.035  116.570 180.945 1.00 104.69 ? 126 TRP A CD1   1 
ATOM   975  C  CD2   . TRP A 1 126 ? 92.382  114.543 180.067 1.00 102.39 ? 126 TRP A CD2   1 
ATOM   976  N  NE1   . TRP A 1 126 ? 92.284  116.731 179.604 1.00 103.40 ? 126 TRP A NE1   1 
ATOM   977  C  CE2   . TRP A 1 126 ? 92.500  115.501 179.043 1.00 99.87  ? 126 TRP A CE2   1 
ATOM   978  C  CE3   . TRP A 1 126 ? 92.560  113.193 179.752 1.00 96.53  ? 126 TRP A CE3   1 
ATOM   979  C  CZ2   . TRP A 1 126 ? 92.789  115.153 177.727 1.00 94.00  ? 126 TRP A CZ2   1 
ATOM   980  C  CZ3   . TRP A 1 126 ? 92.846  112.850 178.446 1.00 93.52  ? 126 TRP A CZ3   1 
ATOM   981  C  CH2   . TRP A 1 126 ? 92.958  113.825 177.449 1.00 92.95  ? 126 TRP A CH2   1 
ATOM   982  N  N     . ARG A 1 127 ? 95.401  114.939 183.145 1.00 93.77  ? 127 ARG A N     1 
ATOM   983  C  CA    . ARG A 1 127 ? 96.434  115.953 183.305 1.00 93.30  ? 127 ARG A CA    1 
ATOM   984  C  C     . ARG A 1 127 ? 96.023  117.229 182.586 1.00 101.18 ? 127 ARG A C     1 
ATOM   985  O  O     . ARG A 1 127 ? 95.576  117.193 181.436 1.00 103.23 ? 127 ARG A O     1 
ATOM   986  C  CB    . ARG A 1 127 ? 97.767  115.441 182.764 1.00 88.07  ? 127 ARG A CB    1 
ATOM   987  C  CG    . ARG A 1 127 ? 98.387  114.340 183.602 1.00 86.91  ? 127 ARG A CG    1 
ATOM   988  C  CD    . ARG A 1 127 ? 99.544  113.680 182.879 1.00 88.42  ? 127 ARG A CD    1 
ATOM   989  N  NE    . ARG A 1 127 ? 99.448  112.226 182.916 1.00 92.23  ? 127 ARG A NE    1 
ATOM   990  C  CZ    . ARG A 1 127 ? 100.407 111.404 182.514 1.00 96.43  ? 127 ARG A CZ    1 
ATOM   991  N  NH1   . ARG A 1 127 ? 101.553 111.861 182.038 1.00 98.39  ? 127 ARG A NH1   1 
ATOM   992  N  NH2   . ARG A 1 127 ? 100.210 110.092 182.591 1.00 98.18  ? 127 ARG A NH2   1 
ATOM   993  N  N     . SER A 1 128 ? 96.174  118.365 183.267 1.00 103.45 ? 128 SER A N     1 
ATOM   994  C  CA    . SER A 1 128 ? 95.687  119.639 182.753 1.00 106.00 ? 128 SER A CA    1 
ATOM   995  C  C     . SER A 1 128 ? 96.791  120.682 182.622 1.00 104.95 ? 128 SER A C     1 
ATOM   996  O  O     . SER A 1 128 ? 96.497  121.881 182.600 1.00 106.50 ? 128 SER A O     1 
ATOM   997  C  CB    . SER A 1 128 ? 94.561  120.173 183.640 1.00 109.07 ? 128 SER A CB    1 
ATOM   998  O  OG    . SER A 1 128 ? 93.621  120.913 182.880 1.00 114.89 ? 128 SER A OG    1 
ATOM   999  N  N     . GLN A 1 129 ? 98.054  120.262 182.547 1.00 104.61 ? 129 GLN A N     1 
ATOM   1000 C  CA    . GLN A 1 129 ? 99.120  121.235 182.317 1.00 109.58 ? 129 GLN A CA    1 
ATOM   1001 C  C     . GLN A 1 129 ? 98.958  121.938 180.975 1.00 111.40 ? 129 GLN A C     1 
ATOM   1002 O  O     . GLN A 1 129 ? 99.013  123.180 180.946 1.00 113.18 ? 129 GLN A O     1 
ATOM   1003 C  CB    . GLN A 1 129 ? 100.489 120.560 182.463 1.00 112.13 ? 129 GLN A CB    1 
ATOM   1004 C  CG    . GLN A 1 129 ? 101.662 121.444 182.072 1.00 116.21 ? 129 GLN A CG    1 
ATOM   1005 C  CD    . GLN A 1 129 ? 101.690 122.751 182.839 1.00 123.02 ? 129 GLN A CD    1 
ATOM   1006 O  OE1   . GLN A 1 129 ? 101.394 123.813 182.290 1.00 120.25 ? 129 GLN A OE1   1 
ATOM   1007 N  NE2   . GLN A 1 129 ? 102.047 122.680 184.115 1.00 127.67 ? 129 GLN A NE2   1 
ATOM   1008 N  N     . PRO A 1 130 ? 98.751  121.246 179.850 1.00 107.81 ? 130 PRO A N     1 
ATOM   1009 C  CA    . PRO A 1 130 ? 98.242  121.935 178.660 1.00 102.75 ? 130 PRO A CA    1 
ATOM   1010 C  C     . PRO A 1 130 ? 96.724  121.866 178.621 1.00 100.79 ? 130 PRO A C     1 
ATOM   1011 O  O     . PRO A 1 130 ? 96.111  120.847 178.943 1.00 100.79 ? 130 PRO A O     1 
ATOM   1012 C  CB    . PRO A 1 130 ? 98.867  121.146 177.499 1.00 89.81  ? 130 PRO A CB    1 
ATOM   1013 C  CG    . PRO A 1 130 ? 99.656  120.012 178.134 1.00 91.18  ? 130 PRO A CG    1 
ATOM   1014 C  CD    . PRO A 1 130 ? 99.134  119.865 179.519 1.00 100.15 ? 130 PRO A CD    1 
ATOM   1015 N  N     . ARG A 1 131 ? 96.109  122.974 178.216 1.00 97.76  ? 131 ARG A N     1 
ATOM   1016 C  CA    . ARG A 1 131 ? 94.656  123.069 178.263 1.00 98.20  ? 131 ARG A CA    1 
ATOM   1017 C  C     . ARG A 1 131 ? 94.011  122.278 177.133 1.00 96.08  ? 131 ARG A C     1 
ATOM   1018 O  O     . ARG A 1 131 ? 93.806  122.805 176.035 1.00 99.02  ? 131 ARG A O     1 
ATOM   1019 C  CB    . ARG A 1 131 ? 94.213  124.532 178.207 1.00 102.57 ? 131 ARG A CB    1 
ATOM   1020 C  CG    . ARG A 1 131 ? 94.187  125.222 179.562 1.00 102.75 ? 131 ARG A CG    1 
ATOM   1021 C  CD    . ARG A 1 131 ? 92.771  125.593 179.975 1.00 109.48 ? 131 ARG A CD    1 
ATOM   1022 N  NE    . ARG A 1 131 ? 92.237  126.701 179.192 1.00 116.93 ? 131 ARG A NE    1 
ATOM   1023 C  CZ    . ARG A 1 131 ? 91.286  126.580 178.275 1.00 118.32 ? 131 ARG A CZ    1 
ATOM   1024 N  NH1   . ARG A 1 131 ? 90.742  125.408 177.995 1.00 115.95 ? 131 ARG A NH1   1 
ATOM   1025 N  NH2   . ARG A 1 131 ? 90.870  127.664 177.626 1.00 118.48 ? 131 ARG A NH2   1 
ATOM   1026 N  N     . TYR A 1 132 ? 93.688  121.014 177.393 1.00 91.67  ? 132 TYR A N     1 
ATOM   1027 C  CA    . TYR A 1 132 ? 92.989  120.162 176.442 1.00 91.34  ? 132 TYR A CA    1 
ATOM   1028 C  C     . TYR A 1 132 ? 91.663  119.721 177.044 1.00 93.54  ? 132 TYR A C     1 
ATOM   1029 O  O     . TYR A 1 132 ? 91.558  119.527 178.260 1.00 97.20  ? 132 TYR A O     1 
ATOM   1030 C  CB    . TYR A 1 132 ? 93.824  118.933 176.067 1.00 93.06  ? 132 TYR A CB    1 
ATOM   1031 C  CG    . TYR A 1 132 ? 94.981  119.231 175.142 1.00 91.98  ? 132 TYR A CG    1 
ATOM   1032 C  CD1   . TYR A 1 132 ? 94.965  120.342 174.313 1.00 92.23  ? 132 TYR A CD1   1 
ATOM   1033 C  CD2   . TYR A 1 132 ? 96.092  118.402 175.103 1.00 85.28  ? 132 TYR A CD2   1 
ATOM   1034 C  CE1   . TYR A 1 132 ? 96.021  120.617 173.470 1.00 87.03  ? 132 TYR A CE1   1 
ATOM   1035 C  CE2   . TYR A 1 132 ? 97.152  118.670 174.264 1.00 80.25  ? 132 TYR A CE2   1 
ATOM   1036 C  CZ    . TYR A 1 132 ? 97.111  119.779 173.451 1.00 83.01  ? 132 TYR A CZ    1 
ATOM   1037 O  OH    . TYR A 1 132 ? 98.166  120.050 172.613 1.00 84.29  ? 132 TYR A OH    1 
ATOM   1038 N  N     . SER A 1 133 ? 90.655  119.568 176.192 1.00 92.71  ? 133 SER A N     1 
ATOM   1039 C  CA    . SER A 1 133 ? 89.334  119.177 176.662 1.00 95.95  ? 133 SER A CA    1 
ATOM   1040 C  C     . SER A 1 133 ? 89.353  117.752 177.198 1.00 97.29  ? 133 SER A C     1 
ATOM   1041 O  O     . SER A 1 133 ? 89.960  116.856 176.607 1.00 97.90  ? 133 SER A O     1 
ATOM   1042 C  CB    . SER A 1 133 ? 88.313  119.298 175.533 1.00 93.31  ? 133 SER A CB    1 
ATOM   1043 O  OG    . SER A 1 133 ? 88.573  118.352 174.511 1.00 92.71  ? 133 SER A OG    1 
ATOM   1044 N  N     . ARG A 1 134 ? 88.686  117.548 178.326 1.00 98.56  ? 134 ARG A N     1 
ATOM   1045 C  CA    . ARG A 1 134 ? 88.581  116.213 178.903 1.00 100.86 ? 134 ARG A CA    1 
ATOM   1046 C  C     . ARG A 1 134 ? 87.561  115.394 178.121 1.00 103.80 ? 134 ARG A C     1 
ATOM   1047 O  O     . ARG A 1 134 ? 86.422  115.838 177.948 1.00 101.14 ? 134 ARG A O     1 
ATOM   1048 C  CB    . ARG A 1 134 ? 88.177  116.290 180.371 1.00 104.04 ? 134 ARG A CB    1 
ATOM   1049 C  CG    . ARG A 1 134 ? 87.995  114.935 181.030 1.00 104.74 ? 134 ARG A CG    1 
ATOM   1050 C  CD    . ARG A 1 134 ? 87.060  115.022 182.221 1.00 105.27 ? 134 ARG A CD    1 
ATOM   1051 N  NE    . ARG A 1 134 ? 87.788  115.210 183.470 1.00 114.78 ? 134 ARG A NE    1 
ATOM   1052 C  CZ    . ARG A 1 134 ? 88.197  114.222 184.253 1.00 117.17 ? 134 ARG A CZ    1 
ATOM   1053 N  NH1   . ARG A 1 134 ? 87.971  112.956 183.943 1.00 110.38 ? 134 ARG A NH1   1 
ATOM   1054 N  NH2   . ARG A 1 134 ? 88.850  114.511 185.375 1.00 118.68 ? 134 ARG A NH2   1 
ATOM   1055 N  N     . PRO A 1 135 ? 87.933  114.214 177.625 1.00 104.87 ? 135 PRO A N     1 
ATOM   1056 C  CA    . PRO A 1 135 ? 86.988  113.416 176.834 1.00 103.27 ? 135 PRO A CA    1 
ATOM   1057 C  C     . PRO A 1 135 ? 85.756  113.037 177.642 1.00 105.73 ? 135 PRO A C     1 
ATOM   1058 O  O     . PRO A 1 135 ? 85.837  112.744 178.837 1.00 104.35 ? 135 PRO A O     1 
ATOM   1059 C  CB    . PRO A 1 135 ? 87.808  112.181 176.444 1.00 101.39 ? 135 PRO A CB    1 
ATOM   1060 C  CG    . PRO A 1 135 ? 89.235  112.599 176.596 1.00 101.76 ? 135 PRO A CG    1 
ATOM   1061 C  CD    . PRO A 1 135 ? 89.254  113.577 177.724 1.00 102.22 ? 135 PRO A CD    1 
ATOM   1062 N  N     . THR A 1 136 ? 84.608  113.048 176.973 1.00 109.75 ? 136 THR A N     1 
ATOM   1063 C  CA    . THR A 1 136 ? 83.331  112.697 177.596 1.00 111.03 ? 136 THR A CA    1 
ATOM   1064 C  C     . THR A 1 136 ? 83.003  111.216 177.417 1.00 112.21 ? 136 THR A C     1 
ATOM   1065 O  O     . THR A 1 136 ? 81.928  110.840 176.951 1.00 111.70 ? 136 THR A O     1 
ATOM   1066 C  CB    . THR A 1 136 ? 82.223  113.583 177.034 1.00 109.18 ? 136 THR A CB    1 
ATOM   1067 O  OG1   . THR A 1 136 ? 80.954  113.151 177.541 1.00 115.07 ? 136 THR A OG1   1 
ATOM   1068 C  CG2   . THR A 1 136 ? 82.215  113.550 175.506 1.00 103.45 ? 136 THR A CG2   1 
ATOM   1069 N  N     . LEU A 1 137 ? 83.937  110.357 177.814 1.00 110.87 ? 137 LEU A N     1 
ATOM   1070 C  CA    . LEU A 1 137 ? 83.782  108.917 177.677 1.00 110.94 ? 137 LEU A CA    1 
ATOM   1071 C  C     . LEU A 1 137 ? 83.975  108.251 179.031 1.00 111.08 ? 137 LEU A C     1 
ATOM   1072 O  O     . LEU A 1 137 ? 84.731  108.735 179.878 1.00 109.40 ? 137 LEU A O     1 
ATOM   1073 C  CB    . LEU A 1 137 ? 84.776  108.341 176.662 1.00 110.43 ? 137 LEU A CB    1 
ATOM   1074 C  CG    . LEU A 1 137 ? 84.336  107.071 175.936 1.00 112.80 ? 137 LEU A CG    1 
ATOM   1075 C  CD1   . LEU A 1 137 ? 83.316  107.397 174.858 1.00 111.52 ? 137 LEU A CD1   1 
ATOM   1076 C  CD2   . LEU A 1 137 ? 85.536  106.357 175.342 1.00 111.06 ? 137 LEU A CD2   1 
ATOM   1077 N  N     . SER A 1 138 ? 83.283  107.137 179.225 1.00 113.01 ? 138 SER A N     1 
ATOM   1078 C  CA    . SER A 1 138 ? 83.359  106.412 180.488 1.00 113.55 ? 138 SER A CA    1 
ATOM   1079 C  C     . SER A 1 138 ? 84.718  105.739 180.620 1.00 113.41 ? 138 SER A C     1 
ATOM   1080 O  O     . SER A 1 138 ? 85.085  104.932 179.757 1.00 114.23 ? 138 SER A O     1 
ATOM   1081 C  CB    . SER A 1 138 ? 82.242  105.377 180.570 1.00 112.63 ? 138 SER A CB    1 
ATOM   1082 O  OG    . SER A 1 138 ? 81.062  105.849 179.944 1.00 109.45 ? 138 SER A OG    1 
ATOM   1083 N  N     . PRO A 1 139 ? 85.494  106.041 181.660 1.00 111.65 ? 139 PRO A N     1 
ATOM   1084 C  CA    . PRO A 1 139 ? 86.813  105.411 181.804 1.00 108.05 ? 139 PRO A CA    1 
ATOM   1085 C  C     . PRO A 1 139 ? 86.706  103.899 181.939 1.00 106.85 ? 139 PRO A C     1 
ATOM   1086 O  O     . PRO A 1 139 ? 85.784  103.374 182.567 1.00 110.18 ? 139 PRO A O     1 
ATOM   1087 C  CB    . PRO A 1 139 ? 87.374  106.052 183.079 1.00 104.25 ? 139 PRO A CB    1 
ATOM   1088 C  CG    . PRO A 1 139 ? 86.620  107.332 183.228 1.00 103.02 ? 139 PRO A CG    1 
ATOM   1089 C  CD    . PRO A 1 139 ? 85.249  107.060 182.693 1.00 109.59 ? 139 PRO A CD    1 
ATOM   1090 N  N     . SER A 1 140 ? 87.669  103.202 181.339 1.00 102.68 ? 140 SER A N     1 
ATOM   1091 C  CA    . SER A 1 140 ? 87.737  101.747 181.382 1.00 104.18 ? 140 SER A CA    1 
ATOM   1092 C  C     . SER A 1 140 ? 89.123  101.286 180.949 1.00 106.09 ? 140 SER A C     1 
ATOM   1093 O  O     . SER A 1 140 ? 89.636  101.748 179.923 1.00 111.02 ? 140 SER A O     1 
ATOM   1094 C  CB    . SER A 1 140 ? 86.664  101.125 180.488 1.00 111.69 ? 140 SER A CB    1 
ATOM   1095 O  OG    . SER A 1 140 ? 86.860  99.729  180.355 1.00 115.05 ? 140 SER A OG    1 
ATOM   1096 N  N     . PRO A 1 141 ? 89.761  100.385 181.700 1.00 106.55 ? 141 PRO A N     1 
ATOM   1097 C  CA    . PRO A 1 141 ? 91.108  99.930  181.313 1.00 107.02 ? 141 PRO A CA    1 
ATOM   1098 C  C     . PRO A 1 141 ? 91.149  99.208  179.978 1.00 108.22 ? 141 PRO A C     1 
ATOM   1099 O  O     . PRO A 1 141 ? 92.231  99.088  179.391 1.00 108.70 ? 141 PRO A O     1 
ATOM   1100 C  CB    . PRO A 1 141 ? 91.526  98.997  182.459 1.00 105.35 ? 141 PRO A CB    1 
ATOM   1101 C  CG    . PRO A 1 141 ? 90.510  99.137  183.523 1.00 108.58 ? 141 PRO A CG    1 
ATOM   1102 C  CD    . PRO A 1 141 ? 89.322  99.870  183.007 1.00 105.91 ? 141 PRO A CD    1 
ATOM   1103 N  N     . ARG A 1 142 ? 90.014  98.718  179.481 1.00 110.76 ? 142 ARG A N     1 
ATOM   1104 C  CA    . ARG A 1 142 ? 89.989  98.010  178.208 1.00 112.81 ? 142 ARG A CA    1 
ATOM   1105 C  C     . ARG A 1 142 ? 89.912  98.943  177.007 1.00 110.77 ? 142 ARG A C     1 
ATOM   1106 O  O     . ARG A 1 142 ? 90.010  98.470  175.870 1.00 112.13 ? 142 ARG A O     1 
ATOM   1107 C  CB    . ARG A 1 142 ? 88.810  97.035  178.178 1.00 121.33 ? 142 ARG A CB    1 
ATOM   1108 C  CG    . ARG A 1 142 ? 89.216  95.582  178.008 1.00 123.54 ? 142 ARG A CG    1 
ATOM   1109 C  CD    . ARG A 1 142 ? 88.095  94.648  178.424 1.00 125.97 ? 142 ARG A CD    1 
ATOM   1110 N  NE    . ARG A 1 142 ? 87.921  94.623  179.871 1.00 133.91 ? 142 ARG A NE    1 
ATOM   1111 C  CZ    . ARG A 1 142 ? 86.808  94.975  180.499 1.00 139.44 ? 142 ARG A CZ    1 
ATOM   1112 N  NH1   . ARG A 1 142 ? 85.738  95.379  179.834 1.00 136.03 ? 142 ARG A NH1   1 
ATOM   1113 N  NH2   . ARG A 1 142 ? 86.765  94.917  181.826 1.00 144.11 ? 142 ARG A NH2   1 
ATOM   1114 N  N     . ARG A 1 143 ? 89.742  100.245 177.226 1.00 111.72 ? 143 ARG A N     1 
ATOM   1115 C  CA    . ARG A 1 143 ? 89.645  101.219 176.149 1.00 112.08 ? 143 ARG A CA    1 
ATOM   1116 C  C     . ARG A 1 143 ? 90.975  101.894 175.840 1.00 106.68 ? 143 ARG A C     1 
ATOM   1117 O  O     . ARG A 1 143 ? 91.011  102.826 175.032 1.00 103.93 ? 143 ARG A O     1 
ATOM   1118 C  CB    . ARG A 1 143 ? 88.594  102.277 176.490 1.00 112.48 ? 143 ARG A CB    1 
ATOM   1119 C  CG    . ARG A 1 143 ? 87.161  101.782 176.421 1.00 112.14 ? 143 ARG A CG    1 
ATOM   1120 C  CD    . ARG A 1 143 ? 86.185  102.942 176.495 1.00 116.70 ? 143 ARG A CD    1 
ATOM   1121 N  NE    . ARG A 1 143 ? 84.958  102.587 177.197 1.00 121.51 ? 143 ARG A NE    1 
ATOM   1122 C  CZ    . ARG A 1 143 ? 83.878  102.091 176.610 1.00 126.40 ? 143 ARG A CZ    1 
ATOM   1123 N  NH1   . ARG A 1 143 ? 83.836  101.878 175.306 1.00 130.18 ? 143 ARG A NH1   1 
ATOM   1124 N  NH2   . ARG A 1 143 ? 82.811  101.803 177.351 1.00 125.56 ? 143 ARG A NH2   1 
ATOM   1125 N  N     . GLN A 1 144 ? 92.063  101.455 176.468 1.00 100.63 ? 144 GLN A N     1 
ATOM   1126 C  CA    . GLN A 1 144 ? 93.356  102.084 176.252 1.00 94.74  ? 144 GLN A CA    1 
ATOM   1127 C  C     . GLN A 1 144 ? 93.841  101.853 174.826 1.00 94.91  ? 144 GLN A C     1 
ATOM   1128 O  O     . GLN A 1 144 ? 93.503  100.856 174.182 1.00 97.23  ? 144 GLN A O     1 
ATOM   1129 C  CB    . GLN A 1 144 ? 94.380  101.547 177.248 1.00 94.99  ? 144 GLN A CB    1 
ATOM   1130 C  CG    . GLN A 1 144 ? 93.960  101.707 178.694 1.00 95.98  ? 144 GLN A CG    1 
ATOM   1131 C  CD    . GLN A 1 144 ? 94.923  101.049 179.653 1.00 101.88 ? 144 GLN A CD    1 
ATOM   1132 O  OE1   . GLN A 1 144 ? 94.516  100.476 180.661 1.00 108.99 ? 144 GLN A OE1   1 
ATOM   1133 N  NE2   . GLN A 1 144 ? 96.211  101.134 179.350 1.00 100.82 ? 144 GLN A NE2   1 
ATOM   1134 N  N     . VAL A 1 145 ? 94.647  102.791 174.335 1.00 92.48  ? 145 VAL A N     1 
ATOM   1135 C  CA    . VAL A 1 145 ? 95.119  102.776 172.957 1.00 89.24  ? 145 VAL A CA    1 
ATOM   1136 C  C     . VAL A 1 145 ? 96.641  102.756 172.954 1.00 84.98  ? 145 VAL A C     1 
ATOM   1137 O  O     . VAL A 1 145 ? 97.292  103.258 173.876 1.00 90.86  ? 145 VAL A O     1 
ATOM   1138 C  CB    . VAL A 1 145 ? 94.567  103.984 172.164 1.00 87.27  ? 145 VAL A CB    1 
ATOM   1139 C  CG1   . VAL A 1 145 ? 95.658  105.000 171.864 1.00 81.37  ? 145 VAL A CG1   1 
ATOM   1140 C  CG2   . VAL A 1 145 ? 93.895  103.519 170.889 1.00 92.20  ? 145 VAL A CG2   1 
ATOM   1141 N  N     . ALA A 1 146 ? 97.209  102.146 171.914 1.00 82.17  ? 146 ALA A N     1 
ATOM   1142 C  CA    . ALA A 1 146 ? 98.651  102.047 171.740 1.00 83.56  ? 146 ALA A CA    1 
ATOM   1143 C  C     . ALA A 1 146 ? 99.023  102.569 170.362 1.00 85.51  ? 146 ALA A C     1 
ATOM   1144 O  O     . ALA A 1 146 ? 98.418  102.175 169.360 1.00 86.70  ? 146 ALA A O     1 
ATOM   1145 C  CB    . ALA A 1 146 ? 99.134  100.605 171.904 1.00 82.51  ? 146 ALA A CB    1 
ATOM   1146 N  N     . VAL A 1 147 ? 100.024 103.443 170.313 1.00 82.31  ? 147 VAL A N     1 
ATOM   1147 C  CA    . VAL A 1 147 ? 100.487 104.054 169.073 1.00 73.25  ? 147 VAL A CA    1 
ATOM   1148 C  C     . VAL A 1 147 ? 101.818 103.417 168.706 1.00 76.39  ? 147 VAL A C     1 
ATOM   1149 O  O     . VAL A 1 147 ? 102.781 103.487 169.479 1.00 82.10  ? 147 VAL A O     1 
ATOM   1150 C  CB    . VAL A 1 147 ? 100.628 105.576 169.213 1.00 67.00  ? 147 VAL A CB    1 
ATOM   1151 C  CG1   . VAL A 1 147 ? 101.370 106.149 168.022 1.00 65.24  ? 147 VAL A CG1   1 
ATOM   1152 C  CG2   . VAL A 1 147 ? 99.265  106.222 169.360 1.00 69.86  ? 147 VAL A CG2   1 
ATOM   1153 N  N     . LEU A 1 148 ? 101.881 102.803 167.527 1.00 75.50  ? 148 LEU A N     1 
ATOM   1154 C  CA    . LEU A 1 148 ? 103.080 102.136 167.046 1.00 69.42  ? 148 LEU A CA    1 
ATOM   1155 C  C     . LEU A 1 148 ? 103.620 102.879 165.835 1.00 69.36  ? 148 LEU A C     1 
ATOM   1156 O  O     . LEU A 1 148 ? 102.882 103.137 164.877 1.00 75.06  ? 148 LEU A O     1 
ATOM   1157 C  CB    . LEU A 1 148 ? 102.787 100.680 166.683 1.00 61.62  ? 148 LEU A CB    1 
ATOM   1158 C  CG    . LEU A 1 148 ? 101.954 99.906  167.701 1.00 70.01  ? 148 LEU A CG    1 
ATOM   1159 C  CD1   . LEU A 1 148 ? 101.443 98.613  167.095 1.00 79.09  ? 148 LEU A CD1   1 
ATOM   1160 C  CD2   . LEU A 1 148 ? 102.771 99.631  168.951 1.00 77.16  ? 148 LEU A CD2   1 
ATOM   1161 N  N     . ASN A 1 149 ? 104.904 103.220 165.885 1.00 59.56  ? 149 ASN A N     1 
ATOM   1162 C  CA    . ASN A 1 149 ? 105.604 103.826 164.756 1.00 60.63  ? 149 ASN A CA    1 
ATOM   1163 C  C     . ASN A 1 149 ? 106.278 102.695 163.990 1.00 66.76  ? 149 ASN A C     1 
ATOM   1164 O  O     . ASN A 1 149 ? 107.359 102.234 164.363 1.00 73.98  ? 149 ASN A O     1 
ATOM   1165 C  CB    . ASN A 1 149 ? 106.608 104.865 165.243 1.00 60.61  ? 149 ASN A CB    1 
ATOM   1166 C  CG    . ASN A 1 149 ? 107.269 105.623 164.108 1.00 62.17  ? 149 ASN A CG    1 
ATOM   1167 O  OD1   . ASN A 1 149 ? 106.958 105.410 162.938 1.00 66.78  ? 149 ASN A OD1   1 
ATOM   1168 N  ND2   . ASN A 1 149 ? 108.189 106.514 164.452 1.00 57.06  ? 149 ASN A ND2   1 
ATOM   1169 N  N     . LEU A 1 150 ? 105.633 102.243 162.919 1.00 61.54  ? 150 LEU A N     1 
ATOM   1170 C  CA    . LEU A 1 150 ? 106.117 101.077 162.197 1.00 61.97  ? 150 LEU A CA    1 
ATOM   1171 C  C     . LEU A 1 150 ? 107.462 101.376 161.537 1.00 64.51  ? 150 LEU A C     1 
ATOM   1172 O  O     . LEU A 1 150 ? 107.690 102.493 161.065 1.00 62.65  ? 150 LEU A O     1 
ATOM   1173 C  CB    . LEU A 1 150 ? 105.099 100.642 161.145 1.00 62.05  ? 150 LEU A CB    1 
ATOM   1174 C  CG    . LEU A 1 150 ? 103.764 100.135 161.696 1.00 61.00  ? 150 LEU A CG    1 
ATOM   1175 C  CD1   . LEU A 1 150 ? 102.975 99.416  160.620 1.00 69.12  ? 150 LEU A CD1   1 
ATOM   1176 C  CD2   . LEU A 1 150 ? 103.987 99.227  162.891 1.00 63.08  ? 150 LEU A CD2   1 
ATOM   1177 N  N     . PRO A 1 151 ? 108.372 100.397 161.486 1.00 70.75  ? 151 PRO A N     1 
ATOM   1178 C  CA    . PRO A 1 151 ? 109.707 100.651 160.928 1.00 70.26  ? 151 PRO A CA    1 
ATOM   1179 C  C     . PRO A 1 151 ? 109.708 100.782 159.414 1.00 75.60  ? 151 PRO A C     1 
ATOM   1180 O  O     . PRO A 1 151 ? 108.653 100.797 158.774 1.00 78.42  ? 151 PRO A O     1 
ATOM   1181 C  CB    . PRO A 1 151 ? 110.522 99.435  161.381 1.00 65.36  ? 151 PRO A CB    1 
ATOM   1182 C  CG    . PRO A 1 151 ? 109.534 98.378  161.669 1.00 71.22  ? 151 PRO A CG    1 
ATOM   1183 C  CD    . PRO A 1 151 ? 108.217 99.019  161.979 1.00 74.30  ? 151 PRO A CD    1 
ATOM   1184 N  N     . ARG A 1 152 ? 110.908 100.886 158.839 1.00 75.01  ? 152 ARG A N     1 
ATOM   1185 C  CA    . ARG A 1 152 ? 111.037 101.188 157.417 1.00 75.70  ? 152 ARG A CA    1 
ATOM   1186 C  C     . ARG A 1 152 ? 110.486 100.065 156.546 1.00 80.49  ? 152 ARG A C     1 
ATOM   1187 O  O     . ARG A 1 152 ? 109.741 100.323 155.594 1.00 81.03  ? 152 ARG A O     1 
ATOM   1188 C  CB    . ARG A 1 152 ? 112.503 101.458 157.082 1.00 72.67  ? 152 ARG A CB    1 
ATOM   1189 C  CG    . ARG A 1 152 ? 112.746 101.974 155.679 1.00 68.46  ? 152 ARG A CG    1 
ATOM   1190 C  CD    . ARG A 1 152 ? 112.125 103.343 155.487 1.00 64.13  ? 152 ARG A CD    1 
ATOM   1191 N  NE    . ARG A 1 152 ? 113.028 104.407 155.907 1.00 63.62  ? 152 ARG A NE    1 
ATOM   1192 C  CZ    . ARG A 1 152 ? 112.924 105.672 155.527 1.00 61.17  ? 152 ARG A CZ    1 
ATOM   1193 N  NH1   . ARG A 1 152 ? 111.972 106.069 154.701 1.00 53.52  ? 152 ARG A NH1   1 
ATOM   1194 N  NH2   . ARG A 1 152 ? 113.800 106.561 155.987 1.00 62.83  ? 152 ARG A NH2   1 
ATOM   1195 N  N     . SER A 1 153 ? 110.828 98.816  156.851 1.00 80.02  ? 153 SER A N     1 
ATOM   1196 C  CA    . SER A 1 153 ? 110.478 97.677  156.006 1.00 80.37  ? 153 SER A CA    1 
ATOM   1197 C  C     . SER A 1 153 ? 109.752 96.610  156.812 1.00 85.57  ? 153 SER A C     1 
ATOM   1198 O  O     . SER A 1 153 ? 110.070 95.421  156.752 1.00 93.31  ? 153 SER A O     1 
ATOM   1199 C  CB    . SER A 1 153 ? 111.720 97.093  155.338 1.00 82.44  ? 153 SER A CB    1 
ATOM   1200 O  OG    . SER A 1 153 ? 111.398 95.932  154.593 1.00 84.27  ? 153 SER A OG    1 
ATOM   1201 N  N     . PHE A 1 154 ? 108.754 97.031  157.584 1.00 81.45  ? 154 PHE A N     1 
ATOM   1202 C  CA    . PHE A 1 154 ? 107.969 96.105  158.383 1.00 82.36  ? 154 PHE A CA    1 
ATOM   1203 C  C     . PHE A 1 154 ? 107.080 95.250  157.480 1.00 89.68  ? 154 PHE A C     1 
ATOM   1204 O  O     . PHE A 1 154 ? 107.101 95.353  156.251 1.00 93.45  ? 154 PHE A O     1 
ATOM   1205 C  CB    . PHE A 1 154 ? 107.128 96.869  159.403 1.00 77.05  ? 154 PHE A CB    1 
ATOM   1206 C  CG    . PHE A 1 154 ? 106.717 96.047  160.589 1.00 80.75  ? 154 PHE A CG    1 
ATOM   1207 C  CD1   . PHE A 1 154 ? 107.559 95.077  161.099 1.00 85.17  ? 154 PHE A CD1   1 
ATOM   1208 C  CD2   . PHE A 1 154 ? 105.483 96.237  161.187 1.00 81.03  ? 154 PHE A CD2   1 
ATOM   1209 C  CE1   . PHE A 1 154 ? 107.184 94.316  162.187 1.00 86.94  ? 154 PHE A CE1   1 
ATOM   1210 C  CE2   . PHE A 1 154 ? 105.103 95.479  162.276 1.00 86.98  ? 154 PHE A CE2   1 
ATOM   1211 C  CZ    . PHE A 1 154 ? 105.955 94.517  162.776 1.00 89.90  ? 154 PHE A CZ    1 
ATOM   1212 N  N     . ASP A 1 155 ? 106.291 94.381  158.107 1.00 91.62  ? 155 ASP A N     1 
ATOM   1213 C  CA    . ASP A 1 155 ? 105.298 93.579  157.407 1.00 90.98  ? 155 ASP A CA    1 
ATOM   1214 C  C     . ASP A 1 155 ? 103.877 93.964  157.785 1.00 92.11  ? 155 ASP A C     1 
ATOM   1215 O  O     . ASP A 1 155 ? 102.987 93.906  156.935 1.00 96.04  ? 155 ASP A O     1 
ATOM   1216 C  CB    . ASP A 1 155 ? 105.530 92.089  157.705 1.00 92.99  ? 155 ASP A CB    1 
ATOM   1217 C  CG    . ASP A 1 155 ? 104.759 91.154  156.775 1.00 99.93  ? 155 ASP A CG    1 
ATOM   1218 O  OD1   . ASP A 1 155 ? 105.184 89.985  156.650 1.00 105.69 ? 155 ASP A OD1   1 
ATOM   1219 O  OD2   . ASP A 1 155 ? 103.759 91.562  156.153 1.00 97.08  ? 155 ASP A OD2   1 
ATOM   1220 N  N     . TRP A 1 156 ? 103.656 94.360  159.043 1.00 91.07  ? 156 TRP A N     1 
ATOM   1221 C  CA    . TRP A 1 156 ? 102.375 94.827  159.571 1.00 95.77  ? 156 TRP A CA    1 
ATOM   1222 C  C     . TRP A 1 156 ? 101.407 93.658  159.726 1.00 98.18  ? 156 TRP A C     1 
ATOM   1223 O  O     . TRP A 1 156 ? 100.343 93.793  160.338 1.00 98.76  ? 156 TRP A O     1 
ATOM   1224 C  CB    . TRP A 1 156 ? 101.799 95.947  158.686 1.00 95.96  ? 156 TRP A CB    1 
ATOM   1225 C  CG    . TRP A 1 156 ? 100.328 95.857  158.412 1.00 94.88  ? 156 TRP A CG    1 
ATOM   1226 C  CD1   . TRP A 1 156 ? 99.313  96.256  159.233 1.00 94.54  ? 156 TRP A CD1   1 
ATOM   1227 C  CD2   . TRP A 1 156 ? 99.707  95.344  157.229 1.00 97.96  ? 156 TRP A CD2   1 
ATOM   1228 N  NE1   . TRP A 1 156 ? 98.099  96.012  158.638 1.00 101.82 ? 156 TRP A NE1   1 
ATOM   1229 C  CE2   . TRP A 1 156 ? 98.314  95.454  157.406 1.00 101.87 ? 156 TRP A CE2   1 
ATOM   1230 C  CE3   . TRP A 1 156 ? 100.193 94.799  156.037 1.00 98.49  ? 156 TRP A CE3   1 
ATOM   1231 C  CZ2   . TRP A 1 156 ? 97.405  95.038  156.439 1.00 98.75  ? 156 TRP A CZ2   1 
ATOM   1232 C  CZ3   . TRP A 1 156 ? 99.288  94.388  155.079 1.00 97.95  ? 156 TRP A CZ3   1 
ATOM   1233 C  CH2   . TRP A 1 156 ? 97.910  94.512  155.284 1.00 95.30  ? 156 TRP A CH2   1 
ATOM   1234 N  N     . VAL A 1 157 ? 101.803 92.486  159.242 1.00 97.16  ? 157 VAL A N     1 
ATOM   1235 C  CA    . VAL A 1 157 ? 101.005 91.286  159.450 1.00 97.46  ? 157 VAL A CA    1 
ATOM   1236 C  C     . VAL A 1 157 ? 101.469 90.540  160.697 1.00 101.85 ? 157 VAL A C     1 
ATOM   1237 O  O     . VAL A 1 157 ? 100.674 89.841  161.335 1.00 107.73 ? 157 VAL A O     1 
ATOM   1238 C  CB    . VAL A 1 157 ? 101.061 90.393  158.198 1.00 97.68  ? 157 VAL A CB    1 
ATOM   1239 C  CG1   . VAL A 1 157 ? 100.348 89.076  158.433 1.00 99.38  ? 157 VAL A CG1   1 
ATOM   1240 C  CG2   . VAL A 1 157 ? 100.453 91.116  157.010 1.00 96.31  ? 157 VAL A CG2   1 
ATOM   1241 N  N     . SER A 1 158 ? 102.738 90.703  161.080 1.00 99.43  ? 158 SER A N     1 
ATOM   1242 C  CA    . SER A 1 158 ? 103.241 90.090  162.302 1.00 102.39 ? 158 SER A CA    1 
ATOM   1243 C  C     . SER A 1 158 ? 102.545 90.628  163.543 1.00 103.03 ? 158 SER A C     1 
ATOM   1244 O  O     . SER A 1 158 ? 102.579 89.974  164.590 1.00 105.41 ? 158 SER A O     1 
ATOM   1245 C  CB    . SER A 1 158 ? 104.748 90.310  162.417 1.00 101.57 ? 158 SER A CB    1 
ATOM   1246 O  OG    . SER A 1 158 ? 105.415 89.878  161.245 1.00 109.42 ? 158 SER A OG    1 
ATOM   1247 N  N     . LEU A 1 159 ? 101.925 91.807  163.454 1.00 95.99  ? 159 LEU A N     1 
ATOM   1248 C  CA    . LEU A 1 159 ? 101.188 92.339  164.594 1.00 91.86  ? 159 LEU A CA    1 
ATOM   1249 C  C     . LEU A 1 159 ? 99.971  91.486  164.923 1.00 95.06  ? 159 LEU A C     1 
ATOM   1250 O  O     . LEU A 1 159 ? 99.612  91.350  166.098 1.00 97.54  ? 159 LEU A O     1 
ATOM   1251 C  CB    . LEU A 1 159 ? 100.762 93.780  164.321 1.00 88.79  ? 159 LEU A CB    1 
ATOM   1252 C  CG    . LEU A 1 159 ? 101.866 94.835  164.248 1.00 85.63  ? 159 LEU A CG    1 
ATOM   1253 C  CD1   . LEU A 1 159 ? 101.268 96.230  164.249 1.00 84.15  ? 159 LEU A CD1   1 
ATOM   1254 C  CD2   . LEU A 1 159 ? 102.837 94.669  165.400 1.00 83.13  ? 159 LEU A CD2   1 
ATOM   1255 N  N     . LEU A 1 160 ? 99.330  90.909  163.911 1.00 96.37  ? 160 LEU A N     1 
ATOM   1256 C  CA    . LEU A 1 160 ? 98.121  90.128  164.125 1.00 100.61 ? 160 LEU A CA    1 
ATOM   1257 C  C     . LEU A 1 160 ? 98.417  88.869  164.932 1.00 105.61 ? 160 LEU A C     1 
ATOM   1258 O  O     . LEU A 1 160 ? 99.531  88.341  164.919 1.00 104.17 ? 160 LEU A O     1 
ATOM   1259 C  CB    . LEU A 1 160 ? 97.489  89.749  162.787 1.00 101.80 ? 160 LEU A CB    1 
ATOM   1260 C  CG    . LEU A 1 160 ? 97.107  90.922  161.886 1.00 102.09 ? 160 LEU A CG    1 
ATOM   1261 C  CD1   . LEU A 1 160 ? 96.380  90.432  160.649 1.00 104.61 ? 160 LEU A CD1   1 
ATOM   1262 C  CD2   . LEU A 1 160 ? 96.255  91.918  162.650 1.00 99.63  ? 160 LEU A CD2   1 
ATOM   1263 N  N     . VAL A 1 161 ? 97.398  88.393  165.641 1.00 110.09 ? 161 VAL A N     1 
ATOM   1264 C  CA    . VAL A 1 161 ? 97.500  87.190  166.462 1.00 110.60 ? 161 VAL A CA    1 
ATOM   1265 C  C     . VAL A 1 161 ? 97.758  85.994  165.554 1.00 112.52 ? 161 VAL A C     1 
ATOM   1266 O  O     . VAL A 1 161 ? 97.312  85.991  164.398 1.00 116.59 ? 161 VAL A O     1 
ATOM   1267 C  CB    . VAL A 1 161 ? 96.233  86.984  167.306 1.00 108.75 ? 161 VAL A CB    1 
ATOM   1268 C  CG1   . VAL A 1 161 ? 96.228  87.932  168.491 1.00 105.07 ? 161 VAL A CG1   1 
ATOM   1269 C  CG2   . VAL A 1 161 ? 94.993  87.187  166.455 1.00 107.35 ? 161 VAL A CG2   1 
ATOM   1270 N  N     . PRO A 1 162 ? 98.476  84.969  166.023 1.00 108.09 ? 162 PRO A N     1 
ATOM   1271 C  CA    . PRO A 1 162 ? 98.781  83.828  165.143 1.00 109.70 ? 162 PRO A CA    1 
ATOM   1272 C  C     . PRO A 1 162 ? 97.549  83.131  164.599 1.00 113.30 ? 162 PRO A C     1 
ATOM   1273 O  O     . PRO A 1 162 ? 97.599  82.588  163.488 1.00 113.18 ? 162 PRO A O     1 
ATOM   1274 C  CB    . PRO A 1 162 ? 99.601  82.900  166.050 1.00 109.39 ? 162 PRO A CB    1 
ATOM   1275 C  CG    . PRO A 1 162 ? 100.157 83.792  167.109 1.00 109.48 ? 162 PRO A CG    1 
ATOM   1276 C  CD    . PRO A 1 162 ? 99.111  84.837  167.344 1.00 105.56 ? 162 PRO A CD    1 
ATOM   1277 N  N     . GLU A 1 163 ? 96.444  83.119  165.348 1.00 115.15 ? 163 GLU A N     1 
ATOM   1278 C  CA    . GLU A 1 163 ? 95.219  82.508  164.843 1.00 115.79 ? 163 GLU A CA    1 
ATOM   1279 C  C     . GLU A 1 163 ? 94.694  83.253  163.622 1.00 117.12 ? 163 GLU A C     1 
ATOM   1280 O  O     . GLU A 1 163 ? 94.239  82.633  162.654 1.00 117.69 ? 163 GLU A O     1 
ATOM   1281 C  CB    . GLU A 1 163 ? 94.161  82.465  165.944 1.00 118.10 ? 163 GLU A CB    1 
ATOM   1282 C  CG    . GLU A 1 163 ? 94.583  81.684  167.179 1.00 123.76 ? 163 GLU A CG    1 
ATOM   1283 C  CD    . GLU A 1 163 ? 94.820  82.576  168.381 1.00 125.35 ? 163 GLU A CD    1 
ATOM   1284 O  OE1   . GLU A 1 163 ? 94.580  83.797  168.273 1.00 123.83 ? 163 GLU A OE1   1 
ATOM   1285 O  OE2   . GLU A 1 163 ? 95.248  82.057  169.433 1.00 128.55 ? 163 GLU A OE2   1 
ATOM   1286 N  N     . SER A 1 164 ? 94.748  84.584  163.648 1.00 116.28 ? 164 SER A N     1 
ATOM   1287 C  CA    . SER A 1 164 ? 94.299  85.398  162.528 1.00 112.52 ? 164 SER A CA    1 
ATOM   1288 C  C     . SER A 1 164 ? 95.397  85.673  161.511 1.00 111.35 ? 164 SER A C     1 
ATOM   1289 O  O     . SER A 1 164 ? 95.111  86.243  160.453 1.00 110.57 ? 164 SER A O     1 
ATOM   1290 C  CB    . SER A 1 164 ? 93.732  86.727  163.036 1.00 110.67 ? 164 SER A CB    1 
ATOM   1291 O  OG    . SER A 1 164 ? 93.828  87.731  162.041 1.00 113.54 ? 164 SER A OG    1 
ATOM   1292 N  N     . GLN A 1 165 ? 96.639  85.294  161.806 1.00 112.56 ? 165 GLN A N     1 
ATOM   1293 C  CA    . GLN A 1 165 ? 97.728  85.412  160.848 1.00 110.18 ? 165 GLN A CA    1 
ATOM   1294 C  C     . GLN A 1 165 ? 97.840  84.202  159.935 1.00 109.36 ? 165 GLN A C     1 
ATOM   1295 O  O     . GLN A 1 165 ? 98.441  84.305  158.857 1.00 107.99 ? 165 GLN A O     1 
ATOM   1296 C  CB    . GLN A 1 165 ? 99.054  85.614  161.587 1.00 108.15 ? 165 GLN A CB    1 
ATOM   1297 C  CG    . GLN A 1 165 ? 100.140 86.278  160.765 1.00 106.17 ? 165 GLN A CG    1 
ATOM   1298 C  CD    . GLN A 1 165 ? 101.376 86.589  161.582 1.00 108.04 ? 165 GLN A CD    1 
ATOM   1299 O  OE1   . GLN A 1 165 ? 101.428 86.314  162.781 1.00 103.97 ? 165 GLN A OE1   1 
ATOM   1300 N  NE2   . GLN A 1 165 ? 102.384 87.161  160.935 1.00 107.76 ? 165 GLN A NE2   1 
ATOM   1301 N  N     . GLU A 1 166 ? 97.272  83.063  160.339 1.00 110.58 ? 166 GLU A N     1 
ATOM   1302 C  CA    . GLU A 1 166 ? 97.367  81.854  159.529 1.00 113.07 ? 166 GLU A CA    1 
ATOM   1303 C  C     . GLU A 1 166 ? 96.629  82.008  158.206 1.00 113.50 ? 166 GLU A C     1 
ATOM   1304 O  O     . GLU A 1 166 ? 97.114  81.552  157.168 1.00 114.62 ? 166 GLU A O     1 
ATOM   1305 C  CB    . GLU A 1 166 ? 96.829  80.655  160.309 1.00 116.08 ? 166 GLU A CB    1 
ATOM   1306 C  CG    . GLU A 1 166 ? 97.722  79.425  160.251 1.00 119.18 ? 166 GLU A CG    1 
ATOM   1307 C  CD    . GLU A 1 166 ? 99.199  79.763  160.341 1.00 122.82 ? 166 GLU A CD    1 
ATOM   1308 O  OE1   . GLU A 1 166 ? 99.596  80.469  161.293 1.00 124.48 ? 166 GLU A OE1   1 
ATOM   1309 O  OE2   . GLU A 1 166 ? 99.963  79.325  159.456 1.00 123.59 ? 166 GLU A OE2   1 
ATOM   1310 N  N     . VAL A 1 167 ? 95.454  82.640  158.223 1.00 111.09 ? 167 VAL A N     1 
ATOM   1311 C  CA    . VAL A 1 167 ? 94.696  82.826  156.988 1.00 111.32 ? 167 VAL A CA    1 
ATOM   1312 C  C     . VAL A 1 167 ? 95.442  83.749  156.028 1.00 111.59 ? 167 VAL A C     1 
ATOM   1313 O  O     . VAL A 1 167 ? 95.511  83.486  154.821 1.00 110.84 ? 167 VAL A O     1 
ATOM   1314 C  CB    . VAL A 1 167 ? 93.281  83.344  157.305 1.00 109.73 ? 167 VAL A CB    1 
ATOM   1315 C  CG1   . VAL A 1 167 ? 93.341  84.504  158.279 1.00 106.98 ? 167 VAL A CG1   1 
ATOM   1316 C  CG2   . VAL A 1 167 ? 92.562  83.751  156.028 1.00 111.81 ? 167 VAL A CG2   1 
ATOM   1317 N  N     . ILE A 1 168 ? 96.013  84.840  156.544 1.00 110.00 ? 168 ILE A N     1 
ATOM   1318 C  CA    . ILE A 1 168 ? 96.776  85.754  155.696 1.00 103.11 ? 168 ILE A CA    1 
ATOM   1319 C  C     . ILE A 1 168 ? 97.997  85.050  155.120 1.00 106.20 ? 168 ILE A C     1 
ATOM   1320 O  O     . ILE A 1 168 ? 98.316  85.198  153.932 1.00 107.07 ? 168 ILE A O     1 
ATOM   1321 C  CB    . ILE A 1 168 ? 97.169  87.015  156.487 1.00 98.53  ? 168 ILE A CB    1 
ATOM   1322 C  CG1   . ILE A 1 168 ? 95.929  87.849  156.808 1.00 100.99 ? 168 ILE A CG1   1 
ATOM   1323 C  CG2   . ILE A 1 168 ? 98.172  87.844  155.707 1.00 93.95  ? 168 ILE A CG2   1 
ATOM   1324 C  CD1   . ILE A 1 168 ? 95.283  88.465  155.592 1.00 100.31 ? 168 ILE A CD1   1 
ATOM   1325 N  N     . GLU A 1 169 ? 98.698  84.273  155.949 1.00 108.74 ? 169 GLU A N     1 
ATOM   1326 C  CA    . GLU A 1 169 ? 99.866  83.546  155.464 1.00 108.07 ? 169 GLU A CA    1 
ATOM   1327 C  C     . GLU A 1 169 ? 99.479  82.513  154.414 1.00 106.62 ? 169 GLU A C     1 
ATOM   1328 O  O     . GLU A 1 169 ? 100.199 82.319  153.430 1.00 108.14 ? 169 GLU A O     1 
ATOM   1329 C  CB    . GLU A 1 169 ? 100.593 82.879  156.631 1.00 113.39 ? 169 GLU A CB    1 
ATOM   1330 C  CG    . GLU A 1 169 ? 102.042 82.532  156.337 1.00 116.84 ? 169 GLU A CG    1 
ATOM   1331 C  CD    . GLU A 1 169 ? 102.668 83.461  155.315 1.00 118.27 ? 169 GLU A CD    1 
ATOM   1332 O  OE1   . GLU A 1 169 ? 102.930 84.634  155.656 1.00 116.14 ? 169 GLU A OE1   1 
ATOM   1333 O  OE2   . GLU A 1 169 ? 102.898 83.019  154.171 1.00 119.62 ? 169 GLU A OE2   1 
ATOM   1334 N  N     . GLU A 1 170 ? 98.346  81.835  154.609 1.00 107.04 ? 170 GLU A N     1 
ATOM   1335 C  CA    . GLU A 1 170 ? 97.879  80.864  153.626 1.00 109.28 ? 170 GLU A CA    1 
ATOM   1336 C  C     . GLU A 1 170 ? 97.531  81.538  152.306 1.00 109.59 ? 170 GLU A C     1 
ATOM   1337 O  O     . GLU A 1 170 ? 97.840  81.011  151.232 1.00 109.68 ? 170 GLU A O     1 
ATOM   1338 C  CB    . GLU A 1 170 ? 96.674  80.102  154.178 1.00 114.19 ? 170 GLU A CB    1 
ATOM   1339 C  CG    . GLU A 1 170 ? 96.106  79.055  153.234 1.00 120.36 ? 170 GLU A CG    1 
ATOM   1340 C  CD    . GLU A 1 170 ? 94.961  79.588  152.394 1.00 123.21 ? 170 GLU A CD    1 
ATOM   1341 O  OE1   . GLU A 1 170 ? 94.207  80.449  152.894 1.00 121.03 ? 170 GLU A OE1   1 
ATOM   1342 O  OE2   . GLU A 1 170 ? 94.818  79.148  151.234 1.00 120.38 ? 170 GLU A OE2   1 
ATOM   1343 N  N     . PHE A 1 171 ? 96.879  82.701  152.366 1.00 109.70 ? 171 PHE A N     1 
ATOM   1344 C  CA    . PHE A 1 171 ? 96.565  83.436  151.144 1.00 105.65 ? 171 PHE A CA    1 
ATOM   1345 C  C     . PHE A 1 171 ? 97.837  83.868  150.423 1.00 101.39 ? 171 PHE A C     1 
ATOM   1346 O  O     . PHE A 1 171 ? 97.942  83.745  149.195 1.00 100.31 ? 171 PHE A O     1 
ATOM   1347 C  CB    . PHE A 1 171 ? 95.690  84.644  151.478 1.00 102.72 ? 171 PHE A CB    1 
ATOM   1348 C  CG    . PHE A 1 171 ? 95.383  85.523  150.300 1.00 98.58  ? 171 PHE A CG    1 
ATOM   1349 C  CD1   . PHE A 1 171 ? 95.065  84.975  149.070 1.00 98.70  ? 171 PHE A CD1   1 
ATOM   1350 C  CD2   . PHE A 1 171 ? 95.403  86.901  150.428 1.00 97.30  ? 171 PHE A CD2   1 
ATOM   1351 C  CE1   . PHE A 1 171 ? 94.779  85.785  147.989 1.00 101.27 ? 171 PHE A CE1   1 
ATOM   1352 C  CE2   . PHE A 1 171 ? 95.117  87.715  149.352 1.00 94.67  ? 171 PHE A CE2   1 
ATOM   1353 C  CZ    . PHE A 1 171 ? 94.806  87.157  148.130 1.00 100.78 ? 171 PHE A CZ    1 
ATOM   1354 N  N     . ARG A 1 172 ? 98.823  84.364  151.175 1.00 102.91 ? 172 ARG A N     1 
ATOM   1355 C  CA    . ARG A 1 172 ? 100.084 84.773  150.566 1.00 102.74 ? 172 ARG A CA    1 
ATOM   1356 C  C     . ARG A 1 172 ? 100.818 83.584  149.957 1.00 104.01 ? 172 ARG A C     1 
ATOM   1357 O  O     . ARG A 1 172 ? 101.433 83.707  148.893 1.00 104.64 ? 172 ARG A O     1 
ATOM   1358 C  CB    . ARG A 1 172 ? 100.966 85.475  151.597 1.00 103.51 ? 172 ARG A CB    1 
ATOM   1359 C  CG    . ARG A 1 172 ? 101.494 86.819  151.135 1.00 100.48 ? 172 ARG A CG    1 
ATOM   1360 C  CD    . ARG A 1 172 ? 100.631 87.955  151.650 1.00 105.42 ? 172 ARG A CD    1 
ATOM   1361 N  NE    . ARG A 1 172 ? 100.814 88.171  153.079 1.00 112.37 ? 172 ARG A NE    1 
ATOM   1362 C  CZ    . ARG A 1 172 ? 101.863 88.778  153.618 1.00 109.34 ? 172 ARG A CZ    1 
ATOM   1363 N  NH1   . ARG A 1 172 ? 102.849 89.248  152.871 1.00 103.54 ? 172 ARG A NH1   1 
ATOM   1364 N  NH2   . ARG A 1 172 ? 101.924 88.916  154.939 1.00 108.02 ? 172 ARG A NH2   1 
ATOM   1365 N  N     . ALA A 1 173 ? 100.777 82.429  150.624 1.00 104.18 ? 173 ALA A N     1 
ATOM   1366 C  CA    . ALA A 1 173 ? 101.428 81.240  150.084 1.00 105.58 ? 173 ALA A CA    1 
ATOM   1367 C  C     . ALA A 1 173 ? 100.719 80.742  148.832 1.00 108.91 ? 173 ALA A C     1 
ATOM   1368 O  O     . ALA A 1 173 ? 101.368 80.282  147.886 1.00 110.88 ? 173 ALA A O     1 
ATOM   1369 C  CB    . ALA A 1 173 ? 101.482 80.142  151.145 1.00 105.65 ? 173 ALA A CB    1 
ATOM   1370 N  N     . GLY A 1 174 ? 99.387  80.815  148.811 1.00 107.61 ? 174 GLY A N     1 
ATOM   1371 C  CA    . GLY A 1 174 ? 98.656  80.440  147.613 1.00 105.78 ? 174 GLY A CA    1 
ATOM   1372 C  C     . GLY A 1 174 ? 98.961  81.354  146.444 1.00 106.19 ? 174 GLY A C     1 
ATOM   1373 O  O     . GLY A 1 174 ? 99.069  80.902  145.302 1.00 107.26 ? 174 GLY A O     1 
ATOM   1374 N  N     . LEU A 1 175 ? 99.098  82.654  146.712 1.00 105.34 ? 175 LEU A N     1 
ATOM   1375 C  CA    . LEU A 1 175 ? 99.526  83.577  145.666 1.00 98.87  ? 175 LEU A CA    1 
ATOM   1376 C  C     . LEU A 1 175 ? 100.953 83.280  145.216 1.00 99.71  ? 175 LEU A C     1 
ATOM   1377 O  O     . LEU A 1 175 ? 101.265 83.365  144.023 1.00 102.85 ? 175 LEU A O     1 
ATOM   1378 C  CB    . LEU A 1 175 ? 99.405  85.020  146.153 1.00 90.27  ? 175 LEU A CB    1 
ATOM   1379 C  CG    . LEU A 1 175 ? 98.059  85.695  145.892 1.00 88.52  ? 175 LEU A CG    1 
ATOM   1380 C  CD1   . LEU A 1 175 ? 98.102  87.155  146.300 1.00 86.21  ? 175 LEU A CD1   1 
ATOM   1381 C  CD2   . LEU A 1 175 ? 97.669  85.555  144.431 1.00 88.01  ? 175 LEU A CD2   1 
ATOM   1382 N  N     . ARG A 1 176 ? 101.831 82.928  146.159 1.00 102.84 ? 176 ARG A N     1 
ATOM   1383 C  CA    . ARG A 1 176 ? 103.228 82.656  145.842 1.00 105.46 ? 176 ARG A CA    1 
ATOM   1384 C  C     . ARG A 1 176 ? 103.406 81.397  145.003 1.00 109.19 ? 176 ARG A C     1 
ATOM   1385 O  O     . ARG A 1 176 ? 104.451 81.241  144.362 1.00 109.74 ? 176 ARG A O     1 
ATOM   1386 C  CB    . ARG A 1 176 ? 104.040 82.534  147.132 1.00 104.13 ? 176 ARG A CB    1 
ATOM   1387 C  CG    . ARG A 1 176 ? 105.532 82.776  146.966 1.00 104.55 ? 176 ARG A CG    1 
ATOM   1388 C  CD    . ARG A 1 176 ? 105.828 84.230  146.647 1.00 103.42 ? 176 ARG A CD    1 
ATOM   1389 N  NE    . ARG A 1 176 ? 106.517 84.379  145.371 1.00 102.26 ? 176 ARG A NE    1 
ATOM   1390 C  CZ    . ARG A 1 176 ? 107.371 85.353  145.091 1.00 105.42 ? 176 ARG A CZ    1 
ATOM   1391 N  NH1   . ARG A 1 176 ? 107.667 86.289  145.978 1.00 106.08 ? 176 ARG A NH1   1 
ATOM   1392 N  NH2   . ARG A 1 176 ? 107.944 85.388  143.891 1.00 104.44 ? 176 ARG A NH2   1 
ATOM   1393 N  N     . LYS A 1 177 ? 102.420 80.497  144.994 1.00 109.44 ? 177 LYS A N     1 
ATOM   1394 C  CA    . LYS A 1 177 ? 102.536 79.280  144.200 1.00 110.08 ? 177 LYS A CA    1 
ATOM   1395 C  C     . LYS A 1 177 ? 102.565 79.566  142.705 1.00 110.21 ? 177 LYS A C     1 
ATOM   1396 O  O     . LYS A 1 177 ? 103.075 78.742  141.939 1.00 111.94 ? 177 LYS A O     1 
ATOM   1397 C  CB    . LYS A 1 177 ? 101.386 78.327  144.523 1.00 110.22 ? 177 LYS A CB    1 
ATOM   1398 C  CG    . LYS A 1 177 ? 101.523 77.615  145.859 1.00 113.49 ? 177 LYS A CG    1 
ATOM   1399 C  CD    . LYS A 1 177 ? 102.831 76.846  145.948 1.00 118.82 ? 177 LYS A CD    1 
ATOM   1400 C  CE    . LYS A 1 177 ? 103.679 77.332  147.113 1.00 119.77 ? 177 LYS A CE    1 
ATOM   1401 N  NZ    . LYS A 1 177 ? 104.973 76.601  147.203 1.00 120.02 ? 177 LYS A NZ    1 
ATOM   1402 N  N     . ASP A 1 178 ? 102.032 80.710  142.276 1.00 109.24 ? 178 ASP A N     1 
ATOM   1403 C  CA    . ASP A 1 178 ? 102.020 81.102  140.874 1.00 107.62 ? 178 ASP A CA    1 
ATOM   1404 C  C     . ASP A 1 178 ? 103.095 82.133  140.551 1.00 105.55 ? 178 ASP A C     1 
ATOM   1405 O  O     . ASP A 1 178 ? 103.036 82.770  139.495 1.00 104.66 ? 178 ASP A O     1 
ATOM   1406 C  CB    . ASP A 1 178 ? 100.643 81.642  140.489 1.00 109.18 ? 178 ASP A CB    1 
ATOM   1407 C  CG    . ASP A 1 178 ? 99.512  80.818  141.067 1.00 115.56 ? 178 ASP A CG    1 
ATOM   1408 O  OD1   . ASP A 1 178 ? 99.746  79.640  141.408 1.00 115.61 ? 178 ASP A OD1   1 
ATOM   1409 O  OD2   . ASP A 1 178 ? 98.388  81.349  141.181 1.00 115.06 ? 178 ASP A OD2   1 
ATOM   1410 N  N     . GLY A 1 179 ? 104.076 82.304  141.430 1.00 105.75 ? 179 GLY A N     1 
ATOM   1411 C  CA    . GLY A 1 179 ? 105.063 83.353  141.245 1.00 101.01 ? 179 GLY A CA    1 
ATOM   1412 C  C     . GLY A 1 179 ? 104.491 84.748  141.373 1.00 100.92 ? 179 GLY A C     1 
ATOM   1413 O  O     . GLY A 1 179 ? 104.803 85.620  140.552 1.00 101.02 ? 179 GLY A O     1 
ATOM   1414 N  N     . LEU A 1 180 ? 103.654 84.980  142.383 1.00 102.17 ? 180 LEU A N     1 
ATOM   1415 C  CA    . LEU A 1 180 ? 103.035 86.281  142.604 1.00 96.75  ? 180 LEU A CA    1 
ATOM   1416 C  C     . LEU A 1 180 ? 103.304 86.763  144.023 1.00 96.03  ? 180 LEU A C     1 
ATOM   1417 O  O     . LEU A 1 180 ? 104.111 86.170  144.744 1.00 100.57 ? 180 LEU A O     1 
ATOM   1418 C  CB    . LEU A 1 180 ? 101.530 86.213  142.344 1.00 95.12  ? 180 LEU A CB    1 
ATOM   1419 C  CG    . LEU A 1 180 ? 101.052 86.586  140.941 1.00 88.25  ? 180 LEU A CG    1 
ATOM   1420 C  CD1   . LEU A 1 180 ? 101.257 85.431  139.984 1.00 89.09  ? 180 LEU A CD1   1 
ATOM   1421 C  CD2   . LEU A 1 180 ? 99.592  87.003  140.972 1.00 87.88  ? 180 LEU A CD2   1 
ATOM   1422 N  N     . GLY A 1 181 ? 102.640 87.838  144.428 1.00 91.68  ? 181 GLY A N     1 
ATOM   1423 C  CA    . GLY A 1 181 ? 102.813 88.352  145.773 1.00 87.36  ? 181 GLY A CA    1 
ATOM   1424 C  C     . GLY A 1 181 ? 101.878 89.514  146.013 1.00 83.24  ? 181 GLY A C     1 
ATOM   1425 O  O     . GLY A 1 181 ? 101.096 89.906  145.141 1.00 85.43  ? 181 GLY A O     1 
ATOM   1426 N  N     . LEU A 1 182 ? 101.970 90.065  147.220 1.00 81.56  ? 182 LEU A N     1 
ATOM   1427 C  CA    . LEU A 1 182 ? 101.166 91.214  147.635 1.00 83.10  ? 182 LEU A CA    1 
ATOM   1428 C  C     . LEU A 1 182 ? 102.073 92.260  148.269 1.00 83.60  ? 182 LEU A C     1 
ATOM   1429 O  O     . LEU A 1 182 ? 102.009 92.506  149.479 1.00 82.24  ? 182 LEU A O     1 
ATOM   1430 C  CB    . LEU A 1 182 ? 100.064 90.789  148.606 1.00 81.45  ? 182 LEU A CB    1 
ATOM   1431 C  CG    . LEU A 1 182 ? 98.685  90.533  148.005 1.00 84.56  ? 182 LEU A CG    1 
ATOM   1432 C  CD1   . LEU A 1 182 ? 97.723  90.070  149.083 1.00 86.29  ? 182 LEU A CD1   1 
ATOM   1433 C  CD2   . LEU A 1 182 ? 98.163  91.780  147.312 1.00 80.81  ? 182 LEU A CD2   1 
ATOM   1434 N  N     . PRO A 1 183 ? 102.932 92.900  147.477 1.00 77.96  ? 183 PRO A N     1 
ATOM   1435 C  CA    . PRO A 1 183 ? 103.829 93.909  148.045 1.00 72.08  ? 183 PRO A CA    1 
ATOM   1436 C  C     . PRO A 1 183 ? 103.070 95.170  148.417 1.00 75.41  ? 183 PRO A C     1 
ATOM   1437 O  O     . PRO A 1 183 ? 102.109 95.558  147.750 1.00 78.28  ? 183 PRO A O     1 
ATOM   1438 C  CB    . PRO A 1 183 ? 104.826 94.169  146.914 1.00 72.58  ? 183 PRO A CB    1 
ATOM   1439 C  CG    . PRO A 1 183 ? 104.045 93.902  145.679 1.00 76.02  ? 183 PRO A CG    1 
ATOM   1440 C  CD    . PRO A 1 183 ? 103.065 92.806  146.012 1.00 75.60  ? 183 PRO A CD    1 
ATOM   1441 N  N     . THR A 1 184 ? 103.514 95.810  149.495 1.00 76.63  ? 184 THR A N     1 
ATOM   1442 C  CA    . THR A 1 184 ? 102.926 97.068  149.930 1.00 74.66  ? 184 THR A CA    1 
ATOM   1443 C  C     . THR A 1 184 ? 103.921 97.788  150.825 1.00 73.01  ? 184 THR A C     1 
ATOM   1444 O  O     . THR A 1 184 ? 104.833 97.178  151.388 1.00 75.57  ? 184 THR A O     1 
ATOM   1445 C  CB    . THR A 1 184 ? 101.600 96.854  150.668 1.00 77.18  ? 184 THR A CB    1 
ATOM   1446 O  OG1   . THR A 1 184 ? 100.973 98.121  150.901 1.00 73.80  ? 184 THR A OG1   1 
ATOM   1447 C  CG2   . THR A 1 184 ? 101.834 96.162  152.000 1.00 72.95  ? 184 THR A CG2   1 
ATOM   1448 N  N     . SER A 1 185 ? 103.735 99.097  150.942 1.00 71.07  ? 185 SER A N     1 
ATOM   1449 C  CA    . SER A 1 185 ? 104.528 99.904  151.854 1.00 76.06  ? 185 SER A CA    1 
ATOM   1450 C  C     . SER A 1 185 ? 103.823 99.984  153.199 1.00 79.72  ? 185 SER A C     1 
ATOM   1451 O  O     . SER A 1 185 ? 102.601 100.148 153.265 1.00 86.11  ? 185 SER A O     1 
ATOM   1452 C  CB    . SER A 1 185 ? 104.750 101.305 151.286 1.00 76.37  ? 185 SER A CB    1 
ATOM   1453 O  OG    . SER A 1 185 ? 105.978 101.384 150.585 1.00 77.19  ? 185 SER A OG    1 
ATOM   1454 N  N     . THR A 1 186 ? 104.594 99.855  154.267 1.00 72.84  ? 186 THR A N     1 
ATOM   1455 C  CA    . THR A 1 186 ? 104.018 99.866  155.604 1.00 70.03  ? 186 THR A CA    1 
ATOM   1456 C  C     . THR A 1 186 ? 103.442 101.243 155.912 1.00 69.59  ? 186 THR A C     1 
ATOM   1457 O  O     . THR A 1 186 ? 104.123 102.253 155.698 1.00 74.18  ? 186 THR A O     1 
ATOM   1458 C  CB    . THR A 1 186 ? 105.071 99.502  156.644 1.00 73.74  ? 186 THR A CB    1 
ATOM   1459 O  OG1   . THR A 1 186 ? 106.024 100.565 156.749 1.00 77.88  ? 186 THR A OG1   1 
ATOM   1460 C  CG2   . THR A 1 186 ? 105.787 98.237  156.236 1.00 79.22  ? 186 THR A CG2   1 
ATOM   1461 N  N     . PRO A 1 187 ? 102.202 101.330 156.392 1.00 65.64  ? 187 PRO A N     1 
ATOM   1462 C  CA    . PRO A 1 187 ? 101.684 102.625 156.841 1.00 64.26  ? 187 PRO A CA    1 
ATOM   1463 C  C     . PRO A 1 187 ? 102.556 103.187 157.953 1.00 60.57  ? 187 PRO A C     1 
ATOM   1464 O  O     . PRO A 1 187 ? 103.029 102.458 158.826 1.00 67.56  ? 187 PRO A O     1 
ATOM   1465 C  CB    . PRO A 1 187 ? 100.271 102.295 157.334 1.00 67.22  ? 187 PRO A CB    1 
ATOM   1466 C  CG    . PRO A 1 187 ? 100.272 100.822 157.564 1.00 71.13  ? 187 PRO A CG    1 
ATOM   1467 C  CD    . PRO A 1 187 ? 101.218 100.251 156.559 1.00 70.73  ? 187 PRO A CD    1 
ATOM   1468 N  N     . ASP A 1 188 ? 102.766 104.503 157.912 1.00 52.17  ? 188 ASP A N     1 
ATOM   1469 C  CA    . ASP A 1 188 ? 103.776 105.116 158.764 1.00 55.23  ? 188 ASP A CA    1 
ATOM   1470 C  C     . ASP A 1 188 ? 103.430 105.042 160.244 1.00 56.34  ? 188 ASP A C     1 
ATOM   1471 O  O     . ASP A 1 188 ? 104.325 105.200 161.080 1.00 63.62  ? 188 ASP A O     1 
ATOM   1472 C  CB    . ASP A 1 188 ? 103.997 106.567 158.345 1.00 55.85  ? 188 ASP A CB    1 
ATOM   1473 C  CG    . ASP A 1 188 ? 105.033 106.702 157.248 1.00 56.17  ? 188 ASP A CG    1 
ATOM   1474 O  OD1   . ASP A 1 188 ? 105.547 105.662 156.787 1.00 60.86  ? 188 ASP A OD1   1 
ATOM   1475 O  OD2   . ASP A 1 188 ? 105.332 107.845 156.843 1.00 53.53  ? 188 ASP A OD2   1 
ATOM   1476 N  N     . LEU A 1 189 ? 102.171 104.796 160.595 1.00 50.99  ? 189 LEU A N     1 
ATOM   1477 C  CA    . LEU A 1 189 ? 101.804 104.679 161.998 1.00 53.54  ? 189 LEU A CA    1 
ATOM   1478 C  C     . LEU A 1 189 ? 100.552 103.827 162.121 1.00 63.20  ? 189 LEU A C     1 
ATOM   1479 O  O     . LEU A 1 189 ? 99.691  103.840 161.239 1.00 71.52  ? 189 LEU A O     1 
ATOM   1480 C  CB    . LEU A 1 189 ? 101.577 106.055 162.630 1.00 51.91  ? 189 LEU A CB    1 
ATOM   1481 C  CG    . LEU A 1 189 ? 101.463 106.120 164.152 1.00 52.55  ? 189 LEU A CG    1 
ATOM   1482 C  CD1   . LEU A 1 189 ? 102.076 107.402 164.656 1.00 55.93  ? 189 LEU A CD1   1 
ATOM   1483 C  CD2   . LEU A 1 189 ? 100.018 106.023 164.588 1.00 58.66  ? 189 LEU A CD2   1 
ATOM   1484 N  N     . ALA A 1 190 ? 100.444 103.104 163.235 1.00 67.25  ? 190 ALA A N     1 
ATOM   1485 C  CA    . ALA A 1 190 ? 99.280  102.268 163.505 1.00 67.82  ? 190 ALA A CA    1 
ATOM   1486 C  C     . ALA A 1 190 ? 98.814  102.497 164.934 1.00 72.74  ? 190 ALA A C     1 
ATOM   1487 O  O     . ALA A 1 190 ? 99.572  102.271 165.881 1.00 75.90  ? 190 ALA A O     1 
ATOM   1488 C  CB    . ALA A 1 190 ? 99.598  100.790 163.274 1.00 67.11  ? 190 ALA A CB    1 
ATOM   1489 N  N     . VAL A 1 191 ? 97.572  102.943 165.090 1.00 74.30  ? 191 VAL A N     1 
ATOM   1490 C  CA    . VAL A 1 191 ? 96.940  103.082 166.394 1.00 76.59  ? 191 VAL A CA    1 
ATOM   1491 C  C     . VAL A 1 191 ? 96.050  101.867 166.598 1.00 86.53  ? 191 VAL A C     1 
ATOM   1492 O  O     . VAL A 1 191 ? 95.132  101.623 165.806 1.00 90.87  ? 191 VAL A O     1 
ATOM   1493 C  CB    . VAL A 1 191 ? 96.130  104.383 166.489 1.00 74.96  ? 191 VAL A CB    1 
ATOM   1494 C  CG1   . VAL A 1 191 ? 95.172  104.325 167.659 1.00 82.55  ? 191 VAL A CG1   1 
ATOM   1495 C  CG2   . VAL A 1 191 ? 97.053  105.575 166.614 1.00 73.95  ? 191 VAL A CG2   1 
ATOM   1496 N  N     . VAL A 1 192 ? 96.324  101.095 167.650 1.00 88.05  ? 192 VAL A N     1 
ATOM   1497 C  CA    . VAL A 1 192 ? 95.618  99.851  167.919 1.00 87.59  ? 192 VAL A CA    1 
ATOM   1498 C  C     . VAL A 1 192 ? 95.081  99.889  169.344 1.00 91.07  ? 192 VAL A C     1 
ATOM   1499 O  O     . VAL A 1 192 ? 95.415  100.768 170.136 1.00 94.59  ? 192 VAL A O     1 
ATOM   1500 C  CB    . VAL A 1 192 ? 96.514  98.612  167.716 1.00 89.08  ? 192 VAL A CB    1 
ATOM   1501 C  CG1   . VAL A 1 192 ? 97.256  98.701  166.395 1.00 91.02  ? 192 VAL A CG1   1 
ATOM   1502 C  CG2   . VAL A 1 192 ? 97.492  98.478  168.864 1.00 85.44  ? 192 VAL A CG2   1 
ATOM   1503 N  N     . VAL A 1 193 ? 94.232  98.921  169.658 1.00 92.74  ? 193 VAL A N     1 
ATOM   1504 C  CA    . VAL A 1 193 ? 93.701  98.762  171.006 1.00 94.29  ? 193 VAL A CA    1 
ATOM   1505 C  C     . VAL A 1 193 ? 94.691  97.935  171.814 1.00 99.68  ? 193 VAL A C     1 
ATOM   1506 O  O     . VAL A 1 193 ? 95.170  96.894  171.347 1.00 105.25 ? 193 VAL A O     1 
ATOM   1507 C  CB    . VAL A 1 193 ? 92.313  98.102  170.979 1.00 96.25  ? 193 VAL A CB    1 
ATOM   1508 C  CG1   . VAL A 1 193 ? 91.909  97.652  172.372 1.00 95.44  ? 193 VAL A CG1   1 
ATOM   1509 C  CG2   . VAL A 1 193 ? 91.284  99.063  170.411 1.00 95.16  ? 193 VAL A CG2   1 
ATOM   1510 N  N     . LEU A 1 194 ? 95.010  98.405  173.015 1.00 96.91  ? 194 LEU A N     1 
ATOM   1511 C  CA    . LEU A 1 194 ? 96.018  97.748  173.835 1.00 100.06 ? 194 LEU A CA    1 
ATOM   1512 C  C     . LEU A 1 194 ? 95.591  96.319  174.157 1.00 105.48 ? 194 LEU A C     1 
ATOM   1513 O  O     . LEU A 1 194 ? 94.441  96.098  174.562 1.00 106.17 ? 194 LEU A O     1 
ATOM   1514 C  CB    . LEU A 1 194 ? 96.244  98.533  175.126 1.00 95.91  ? 194 LEU A CB    1 
ATOM   1515 C  CG    . LEU A 1 194 ? 97.580  98.322  175.837 1.00 98.10  ? 194 LEU A CG    1 
ATOM   1516 C  CD1   . LEU A 1 194 ? 98.737  98.567  174.891 1.00 96.71  ? 194 LEU A CD1   1 
ATOM   1517 C  CD2   . LEU A 1 194 ? 97.685  99.224  177.050 1.00 98.62  ? 194 LEU A CD2   1 
ATOM   1518 N  N     . PRO A 1 195 ? 96.468  95.330  173.980 1.00 105.24 ? 195 PRO A N     1 
ATOM   1519 C  CA    . PRO A 1 195 ? 96.110  93.955  174.345 1.00 110.55 ? 195 PRO A CA    1 
ATOM   1520 C  C     . PRO A 1 195 ? 95.831  93.838  175.835 1.00 115.11 ? 195 PRO A C     1 
ATOM   1521 O  O     . PRO A 1 195 ? 96.404  94.558  176.655 1.00 117.13 ? 195 PRO A O     1 
ATOM   1522 C  CB    . PRO A 1 195 ? 97.347  93.144  173.940 1.00 109.07 ? 195 PRO A CB    1 
ATOM   1523 C  CG    . PRO A 1 195 ? 98.061  93.999  172.947 1.00 101.71 ? 195 PRO A CG    1 
ATOM   1524 C  CD    . PRO A 1 195 ? 97.804  95.410  173.370 1.00 99.65  ? 195 PRO A CD    1 
ATOM   1525 N  N     . GLU A 1 196 ? 94.931  92.913  176.177 1.00 116.46 ? 196 GLU A N     1 
ATOM   1526 C  CA    . GLU A 1 196 ? 94.460  92.807  177.555 1.00 117.51 ? 196 GLU A CA    1 
ATOM   1527 C  C     . GLU A 1 196 ? 95.588  92.472  178.523 1.00 114.50 ? 196 GLU A C     1 
ATOM   1528 O  O     . GLU A 1 196 ? 95.526  92.849  179.699 1.00 115.74 ? 196 GLU A O     1 
ATOM   1529 C  CB    . GLU A 1 196 ? 93.349  91.761  177.648 1.00 119.72 ? 196 GLU A CB    1 
ATOM   1530 C  CG    . GLU A 1 196 ? 92.344  92.026  178.756 1.00 122.13 ? 196 GLU A CG    1 
ATOM   1531 C  CD    . GLU A 1 196 ? 90.911  91.856  178.293 1.00 127.77 ? 196 GLU A CD    1 
ATOM   1532 O  OE1   . GLU A 1 196 ? 90.679  91.849  177.066 1.00 128.18 ? 196 GLU A OE1   1 
ATOM   1533 O  OE2   . GLU A 1 196 ? 90.017  91.730  179.156 1.00 133.58 ? 196 GLU A OE2   1 
ATOM   1534 N  N     . GLU A 1 197 ? 96.624  91.773  178.058 1.00 110.92 ? 197 GLU A N     1 
ATOM   1535 C  CA    . GLU A 1 197 ? 97.735  91.428  178.935 1.00 116.17 ? 197 GLU A CA    1 
ATOM   1536 C  C     . GLU A 1 197 ? 98.689  92.593  179.168 1.00 115.41 ? 197 GLU A C     1 
ATOM   1537 O  O     . GLU A 1 197 ? 99.508  92.528  180.090 1.00 116.22 ? 197 GLU A O     1 
ATOM   1538 C  CB    . GLU A 1 197 ? 98.499  90.228  178.370 1.00 118.07 ? 197 GLU A CB    1 
ATOM   1539 C  CG    . GLU A 1 197 ? 99.363  90.541  177.166 1.00 115.91 ? 197 GLU A CG    1 
ATOM   1540 C  CD    . GLU A 1 197 ? 99.254  89.483  176.086 1.00 117.19 ? 197 GLU A CD    1 
ATOM   1541 O  OE1   . GLU A 1 197 ? 98.127  89.232  175.609 1.00 116.32 ? 197 GLU A OE1   1 
ATOM   1542 O  OE2   . GLU A 1 197 ? 100.294 88.899  175.717 1.00 120.16 ? 197 GLU A OE2   1 
ATOM   1543 N  N     . PHE A 1 198 ? 98.607  93.649  178.361 1.00 113.99 ? 198 PHE A N     1 
ATOM   1544 C  CA    . PHE A 1 198 ? 99.406  94.851  178.554 1.00 110.73 ? 198 PHE A CA    1 
ATOM   1545 C  C     . PHE A 1 198 ? 98.643  95.970  179.248 1.00 114.68 ? 198 PHE A C     1 
ATOM   1546 O  O     . PHE A 1 198 ? 99.208  97.048  179.455 1.00 115.43 ? 198 PHE A O     1 
ATOM   1547 C  CB    . PHE A 1 198 ? 99.939  95.361  177.211 1.00 108.14 ? 198 PHE A CB    1 
ATOM   1548 C  CG    . PHE A 1 198 ? 101.184 94.665  176.747 1.00 109.66 ? 198 PHE A CG    1 
ATOM   1549 C  CD1   . PHE A 1 198 ? 101.124 93.402  176.187 1.00 110.93 ? 198 PHE A CD1   1 
ATOM   1550 C  CD2   . PHE A 1 198 ? 102.418 95.281  176.865 1.00 112.61 ? 198 PHE A CD2   1 
ATOM   1551 C  CE1   . PHE A 1 198 ? 102.270 92.765  175.760 1.00 110.33 ? 198 PHE A CE1   1 
ATOM   1552 C  CE2   . PHE A 1 198 ? 103.567 94.648  176.438 1.00 112.35 ? 198 PHE A CE2   1 
ATOM   1553 C  CZ    . PHE A 1 198 ? 103.493 93.388  175.885 1.00 110.32 ? 198 PHE A CZ    1 
ATOM   1554 N  N     . GLN A 1 199 ? 97.384  95.746  179.615 1.00 114.87 ? 199 GLN A N     1 
ATOM   1555 C  CA    . GLN A 1 199 ? 96.529  96.803  180.141 1.00 109.68 ? 199 GLN A CA    1 
ATOM   1556 C  C     . GLN A 1 199 ? 96.849  97.181  181.581 1.00 114.02 ? 199 GLN A C     1 
ATOM   1557 O  O     . GLN A 1 199 ? 96.083  97.935  182.190 1.00 114.96 ? 199 GLN A O     1 
ATOM   1558 C  CB    . GLN A 1 199 ? 95.061  96.392  180.025 1.00 107.96 ? 199 GLN A CB    1 
ATOM   1559 C  CG    . GLN A 1 199 ? 94.572  96.315  178.593 1.00 108.19 ? 199 GLN A CG    1 
ATOM   1560 C  CD    . GLN A 1 199 ? 93.068  96.202  178.494 1.00 113.80 ? 199 GLN A CD    1 
ATOM   1561 O  OE1   . GLN A 1 199 ? 92.368  96.185  179.505 1.00 116.43 ? 199 GLN A OE1   1 
ATOM   1562 N  NE2   . GLN A 1 199 ? 92.561  96.123  177.270 1.00 111.32 ? 199 GLN A NE2   1 
ATOM   1563 N  N     . ASN A 1 200 ? 97.949  96.680  182.141 1.00 117.56 ? 200 ASN A N     1 
ATOM   1564 C  CA    . ASN A 1 200 ? 98.405  97.097  183.457 1.00 118.09 ? 200 ASN A CA    1 
ATOM   1565 C  C     . ASN A 1 200 ? 99.824  97.643  183.454 1.00 116.34 ? 200 ASN A C     1 
ATOM   1566 O  O     . ASN A 1 200 ? 100.298 98.087  184.506 1.00 116.50 ? 200 ASN A O     1 
ATOM   1567 C  CB    . ASN A 1 200 ? 98.315  95.930  184.454 1.00 119.67 ? 200 ASN A CB    1 
ATOM   1568 C  CG    . ASN A 1 200 ? 97.923  96.384  185.848 1.00 121.42 ? 200 ASN A CG    1 
ATOM   1569 O  OD1   . ASN A 1 200 ? 98.687  97.063  186.532 1.00 123.32 ? 200 ASN A OD1   1 
ATOM   1570 N  ND2   . ASN A 1 200 ? 96.722  96.010  186.273 1.00 120.72 ? 200 ASN A ND2   1 
ATOM   1571 N  N     . ASP A 1 201 ? 100.511 97.623  182.315 1.00 113.45 ? 201 ASP A N     1 
ATOM   1572 C  CA    . ASP A 1 201 ? 101.863 98.157  182.242 1.00 114.81 ? 201 ASP A CA    1 
ATOM   1573 C  C     . ASP A 1 201 ? 101.850 99.669  182.422 1.00 111.89 ? 201 ASP A C     1 
ATOM   1574 O  O     . ASP A 1 201 ? 100.984 100.368 181.890 1.00 108.36 ? 201 ASP A O     1 
ATOM   1575 C  CB    . ASP A 1 201 ? 102.504 97.794  180.904 1.00 114.94 ? 201 ASP A CB    1 
ATOM   1576 C  CG    . ASP A 1 201 ? 103.657 96.822  181.054 1.00 120.61 ? 201 ASP A CG    1 
ATOM   1577 O  OD1   . ASP A 1 201 ? 104.437 96.669  180.090 1.00 120.55 ? 201 ASP A OD1   1 
ATOM   1578 O  OD2   . ASP A 1 201 ? 103.782 96.206  182.133 1.00 122.63 ? 201 ASP A OD2   1 
ATOM   1579 N  N     . GLU A 1 202 ? 102.821 100.174 183.179 1.00 111.88 ? 202 GLU A N     1 
ATOM   1580 C  CA    . GLU A 1 202 ? 102.963 101.604 183.409 1.00 110.58 ? 202 GLU A CA    1 
ATOM   1581 C  C     . GLU A 1 202 ? 103.763 102.297 182.316 1.00 105.95 ? 202 GLU A C     1 
ATOM   1582 O  O     . GLU A 1 202 ? 103.919 103.521 182.362 1.00 106.55 ? 202 GLU A O     1 
ATOM   1583 C  CB    . GLU A 1 202 ? 103.625 101.855 184.768 1.00 114.30 ? 202 GLU A CB    1 
ATOM   1584 C  CG    . GLU A 1 202 ? 102.883 102.846 185.648 1.00 120.07 ? 202 GLU A CG    1 
ATOM   1585 C  CD    . GLU A 1 202 ? 103.437 102.900 187.058 1.00 127.74 ? 202 GLU A CD    1 
ATOM   1586 O  OE1   . GLU A 1 202 ? 104.674 102.976 187.208 1.00 126.08 ? 202 GLU A OE1   1 
ATOM   1587 O  OE2   . GLU A 1 202 ? 102.635 102.866 188.016 1.00 131.31 ? 202 GLU A OE2   1 
ATOM   1588 N  N     . MET A 1 203 ? 104.271 101.545 181.341 1.00 103.08 ? 203 MET A N     1 
ATOM   1589 C  CA    . MET A 1 203 ? 105.032 102.131 180.244 1.00 103.18 ? 203 MET A CA    1 
ATOM   1590 C  C     . MET A 1 203 ? 104.145 102.895 179.269 1.00 104.36 ? 203 MET A C     1 
ATOM   1591 O  O     . MET A 1 203 ? 104.562 103.930 178.738 1.00 102.20 ? 203 MET A O     1 
ATOM   1592 C  CB    . MET A 1 203 ? 105.808 101.033 179.517 1.00 103.54 ? 203 MET A CB    1 
ATOM   1593 C  CG    . MET A 1 203 ? 106.375 101.438 178.175 1.00 104.24 ? 203 MET A CG    1 
ATOM   1594 S  SD    . MET A 1 203 ? 107.298 100.076 177.458 1.00 115.09 ? 203 MET A SD    1 
ATOM   1595 C  CE    . MET A 1 203 ? 105.939 98.987  177.070 1.00 109.60 ? 203 MET A CE    1 
ATOM   1596 N  N     . TRP A 1 204 ? 102.926 102.414 179.029 1.00 104.19 ? 204 TRP A N     1 
ATOM   1597 C  CA    . TRP A 1 204 ? 101.997 103.054 178.109 1.00 99.17  ? 204 TRP A CA    1 
ATOM   1598 C  C     . TRP A 1 204 ? 101.183 104.158 178.771 1.00 98.43  ? 204 TRP A C     1 
ATOM   1599 O  O     . TRP A 1 204 ? 100.105 104.502 178.274 1.00 97.04  ? 204 TRP A O     1 
ATOM   1600 C  CB    . TRP A 1 204 ? 101.056 102.013 177.501 1.00 93.93  ? 204 TRP A CB    1 
ATOM   1601 C  CG    . TRP A 1 204 ? 101.748 100.800 176.968 1.00 99.43  ? 204 TRP A CG    1 
ATOM   1602 C  CD1   . TRP A 1 204 ? 102.096 99.682  177.667 1.00 106.91 ? 204 TRP A CD1   1 
ATOM   1603 C  CD2   . TRP A 1 204 ? 102.163 100.574 175.617 1.00 101.69 ? 204 TRP A CD2   1 
ATOM   1604 N  NE1   . TRP A 1 204 ? 102.709 98.777  176.837 1.00 109.43 ? 204 TRP A NE1   1 
ATOM   1605 C  CE2   . TRP A 1 204 ? 102.763 99.301  175.572 1.00 105.83 ? 204 TRP A CE2   1 
ATOM   1606 C  CE3   . TRP A 1 204 ? 102.089 101.325 174.442 1.00 99.59  ? 204 TRP A CE3   1 
ATOM   1607 C  CZ2   . TRP A 1 204 ? 103.286 98.764  174.399 1.00 99.70  ? 204 TRP A CZ2   1 
ATOM   1608 C  CZ3   . TRP A 1 204 ? 102.608 100.790 173.279 1.00 96.82  ? 204 TRP A CZ3   1 
ATOM   1609 C  CH2   . TRP A 1 204 ? 103.199 99.523  173.266 1.00 95.50  ? 204 TRP A CH2   1 
ATOM   1610 N  N     . ARG A 1 205 ? 101.669 104.717 179.881 1.00 97.22  ? 205 ARG A N     1 
ATOM   1611 C  CA    . ARG A 1 205 ? 100.938 105.746 180.607 1.00 95.58  ? 205 ARG A CA    1 
ATOM   1612 C  C     . ARG A 1 205 ? 101.826 106.898 181.058 1.00 96.08  ? 205 ARG A C     1 
ATOM   1613 O  O     . ARG A 1 205 ? 101.354 107.771 181.795 1.00 99.16  ? 205 ARG A O     1 
ATOM   1614 C  CB    . ARG A 1 205 ? 100.225 105.142 181.821 1.00 96.34  ? 205 ARG A CB    1 
ATOM   1615 C  CG    . ARG A 1 205 ? 98.855  104.573 181.512 1.00 95.45  ? 205 ARG A CG    1 
ATOM   1616 C  CD    . ARG A 1 205 ? 98.698  103.183 182.095 1.00 98.62  ? 205 ARG A CD    1 
ATOM   1617 N  NE    . ARG A 1 205 ? 98.834  103.182 183.546 1.00 109.49 ? 205 ARG A NE    1 
ATOM   1618 C  CZ    . ARG A 1 205 ? 98.750  102.097 184.303 1.00 116.08 ? 205 ARG A CZ    1 
ATOM   1619 N  NH1   . ARG A 1 205 ? 98.531  100.903 183.777 1.00 118.14 ? 205 ARG A NH1   1 
ATOM   1620 N  NH2   . ARG A 1 205 ? 98.892  102.212 185.620 1.00 114.68 ? 205 ARG A NH2   1 
ATOM   1621 N  N     . GLU A 1 206 ? 103.089 106.929 180.647 1.00 97.45  ? 206 GLU A N     1 
ATOM   1622 C  CA    . GLU A 1 206 ? 104.005 108.001 181.013 1.00 97.79  ? 206 GLU A CA    1 
ATOM   1623 C  C     . GLU A 1 206 ? 104.346 108.807 179.769 1.00 92.16  ? 206 GLU A C     1 
ATOM   1624 O  O     . GLU A 1 206 ? 104.855 108.256 178.787 1.00 90.70  ? 206 GLU A O     1 
ATOM   1625 C  CB    . GLU A 1 206 ? 105.275 107.448 181.661 1.00 103.52 ? 206 GLU A CB    1 
ATOM   1626 C  CG    . GLU A 1 206 ? 105.731 106.106 181.116 1.00 104.60 ? 206 GLU A CG    1 
ATOM   1627 C  CD    . GLU A 1 206 ? 106.640 105.368 182.079 1.00 103.98 ? 206 GLU A CD    1 
ATOM   1628 O  OE1   . GLU A 1 206 ? 106.309 105.306 183.282 1.00 105.64 ? 206 GLU A OE1   1 
ATOM   1629 O  OE2   . GLU A 1 206 ? 107.685 104.850 181.634 1.00 101.19 ? 206 GLU A OE2   1 
ATOM   1630 N  N     . GLU A 1 207 ? 104.065 110.106 179.815 1.00 85.52  ? 207 GLU A N     1 
ATOM   1631 C  CA    . GLU A 1 207 ? 104.405 110.987 178.707 1.00 77.68  ? 207 GLU A CA    1 
ATOM   1632 C  C     . GLU A 1 207 ? 105.908 111.223 178.669 1.00 79.22  ? 207 GLU A C     1 
ATOM   1633 O  O     . GLU A 1 207 ? 106.529 111.504 179.699 1.00 82.45  ? 207 GLU A O     1 
ATOM   1634 C  CB    . GLU A 1 207 ? 103.664 112.316 178.840 1.00 76.82  ? 207 GLU A CB    1 
ATOM   1635 C  CG    . GLU A 1 207 ? 102.156 112.208 178.705 1.00 79.91  ? 207 GLU A CG    1 
ATOM   1636 C  CD    . GLU A 1 207 ? 101.456 113.528 178.961 1.00 84.16  ? 207 GLU A CD    1 
ATOM   1637 O  OE1   . GLU A 1 207 ? 102.148 114.515 179.287 1.00 88.64  ? 207 GLU A OE1   1 
ATOM   1638 O  OE2   . GLU A 1 207 ? 100.215 113.580 178.838 1.00 80.14  ? 207 GLU A OE2   1 
ATOM   1639 N  N     . ILE A 1 208 ? 106.493 111.110 177.483 1.00 79.53  ? 208 ILE A N     1 
ATOM   1640 C  CA    . ILE A 1 208 ? 107.919 111.354 177.312 1.00 79.84  ? 208 ILE A CA    1 
ATOM   1641 C  C     . ILE A 1 208 ? 108.179 112.853 177.359 1.00 75.57  ? 208 ILE A C     1 
ATOM   1642 O  O     . ILE A 1 208 ? 107.436 113.648 176.773 1.00 75.91  ? 208 ILE A O     1 
ATOM   1643 C  CB    . ILE A 1 208 ? 108.424 110.734 175.997 1.00 71.71  ? 208 ILE A CB    1 
ATOM   1644 C  CG1   . ILE A 1 208 ? 107.511 111.121 174.835 1.00 64.78  ? 208 ILE A CG1   1 
ATOM   1645 C  CG2   . ILE A 1 208 ? 108.506 109.224 176.120 1.00 71.42  ? 208 ILE A CG2   1 
ATOM   1646 C  CD1   . ILE A 1 208 ? 108.007 110.641 173.495 1.00 59.77  ? 208 ILE A CD1   1 
ATOM   1647 N  N     . ALA A 1 209 ? 109.236 113.246 178.069 1.00 73.67  ? 209 ALA A N     1 
ATOM   1648 C  CA    . ALA A 1 209 ? 109.559 114.660 178.209 1.00 74.80  ? 209 ALA A CA    1 
ATOM   1649 C  C     . ALA A 1 209 ? 110.201 115.244 176.960 1.00 74.42  ? 209 ALA A C     1 
ATOM   1650 O  O     . ALA A 1 209 ? 110.256 116.471 176.826 1.00 76.17  ? 209 ALA A O     1 
ATOM   1651 C  CB    . ALA A 1 209 ? 110.484 114.874 179.407 1.00 78.37  ? 209 ALA A CB    1 
ATOM   1652 N  N     . GLY A 1 210 ? 110.684 114.407 176.053 1.00 69.75  ? 210 GLY A N     1 
ATOM   1653 C  CA    . GLY A 1 210 ? 111.292 114.894 174.829 1.00 68.36  ? 210 GLY A CA    1 
ATOM   1654 C  C     . GLY A 1 210 ? 111.695 113.727 173.960 1.00 67.89  ? 210 GLY A C     1 
ATOM   1655 O  O     . GLY A 1 210 ? 111.593 112.562 174.355 1.00 75.81  ? 210 GLY A O     1 
ATOM   1656 N  N     . LEU A 1 211 ? 112.157 114.059 172.757 1.00 61.17  ? 211 LEU A N     1 
ATOM   1657 C  CA    . LEU A 1 211 ? 112.582 113.043 171.795 1.00 62.57  ? 211 LEU A CA    1 
ATOM   1658 C  C     . LEU A 1 211 ? 114.090 112.806 171.893 1.00 63.93  ? 211 LEU A C     1 
ATOM   1659 O  O     . LEU A 1 211 ? 114.838 112.929 170.925 1.00 63.00  ? 211 LEU A O     1 
ATOM   1660 C  CB    . LEU A 1 211 ? 112.177 113.448 170.383 1.00 57.23  ? 211 LEU A CB    1 
ATOM   1661 C  CG    . LEU A 1 211 ? 110.931 112.773 169.817 1.00 52.95  ? 211 LEU A CG    1 
ATOM   1662 C  CD1   . LEU A 1 211 ? 110.342 113.606 168.697 1.00 54.50  ? 211 LEU A CD1   1 
ATOM   1663 C  CD2   . LEU A 1 211 ? 111.257 111.377 169.330 1.00 54.20  ? 211 LEU A CD2   1 
ATOM   1664 N  N     . THR A 1 212 ? 114.528 112.451 173.097 1.00 66.76  ? 212 THR A N     1 
ATOM   1665 C  CA    . THR A 1 212 ? 115.913 112.064 173.294 1.00 68.35  ? 212 THR A CA    1 
ATOM   1666 C  C     . THR A 1 212 ? 116.170 110.703 172.652 1.00 68.85  ? 212 THR A C     1 
ATOM   1667 O  O     . THR A 1 212 ? 115.245 109.974 172.286 1.00 73.07  ? 212 THR A O     1 
ATOM   1668 C  CB    . THR A 1 212 ? 116.257 112.025 174.782 1.00 71.73  ? 212 THR A CB    1 
ATOM   1669 O  OG1   . THR A 1 212 ? 115.141 111.512 175.519 1.00 71.45  ? 212 THR A OG1   1 
ATOM   1670 C  CG2   . THR A 1 212 ? 116.593 113.418 175.286 1.00 69.72  ? 212 THR A CG2   1 
ATOM   1671 N  N     . ARG A 1 213 ? 117.451 110.364 172.514 1.00 70.38  ? 213 ARG A N     1 
ATOM   1672 C  CA    . ARG A 1 213 ? 117.814 109.096 171.884 1.00 73.38  ? 213 ARG A CA    1 
ATOM   1673 C  C     . ARG A 1 213 ? 117.212 107.887 172.593 1.00 78.95  ? 213 ARG A C     1 
ATOM   1674 O  O     . ARG A 1 213 ? 116.682 106.998 171.902 1.00 82.80  ? 213 ARG A O     1 
ATOM   1675 C  CB    . ARG A 1 213 ? 119.339 108.993 171.783 1.00 75.42  ? 213 ARG A CB    1 
ATOM   1676 C  CG    . ARG A 1 213 ? 119.830 107.716 171.130 1.00 77.09  ? 213 ARG A CG    1 
ATOM   1677 C  CD    . ARG A 1 213 ? 119.612 107.742 169.630 1.00 78.97  ? 213 ARG A CD    1 
ATOM   1678 N  NE    . ARG A 1 213 ? 118.714 106.678 169.198 1.00 85.75  ? 213 ARG A NE    1 
ATOM   1679 C  CZ    . ARG A 1 213 ? 118.582 106.274 167.942 1.00 84.07  ? 213 ARG A CZ    1 
ATOM   1680 N  NH1   . ARG A 1 213 ? 119.280 106.823 166.962 1.00 84.80  ? 213 ARG A NH1   1 
ATOM   1681 N  NH2   . ARG A 1 213 ? 117.727 105.294 167.662 1.00 78.98  ? 213 ARG A NH2   1 
ATOM   1682 N  N     . PRO A 1 214 ? 117.255 107.771 173.929 1.00 77.84  ? 214 PRO A N     1 
ATOM   1683 C  CA    . PRO A 1 214 ? 116.511 106.671 174.566 1.00 75.00  ? 214 PRO A CA    1 
ATOM   1684 C  C     . PRO A 1 214 ? 115.025 106.705 174.262 1.00 74.50  ? 214 PRO A C     1 
ATOM   1685 O  O     . PRO A 1 214 ? 114.415 105.652 174.041 1.00 73.13  ? 214 PRO A O     1 
ATOM   1686 C  CB    . PRO A 1 214 ? 116.793 106.877 176.060 1.00 72.97  ? 214 PRO A CB    1 
ATOM   1687 C  CG    . PRO A 1 214 ? 118.068 107.625 176.102 1.00 78.00  ? 214 PRO A CG    1 
ATOM   1688 C  CD    . PRO A 1 214 ? 118.036 108.536 174.918 1.00 74.04  ? 214 PRO A CD    1 
ATOM   1689 N  N     . ASN A 1 215 ? 114.424 107.896 174.213 1.00 72.24  ? 215 ASN A N     1 
ATOM   1690 C  CA    . ASN A 1 215 ? 113.005 107.983 173.891 1.00 69.98  ? 215 ASN A CA    1 
ATOM   1691 C  C     . ASN A 1 215 ? 112.745 107.688 172.420 1.00 72.13  ? 215 ASN A C     1 
ATOM   1692 O  O     . ASN A 1 215 ? 111.701 107.120 172.082 1.00 73.47  ? 215 ASN A O     1 
ATOM   1693 C  CB    . ASN A 1 215 ? 112.464 109.360 174.267 1.00 68.58  ? 215 ASN A CB    1 
ATOM   1694 C  CG    . ASN A 1 215 ? 112.355 109.549 175.765 1.00 74.62  ? 215 ASN A CG    1 
ATOM   1695 O  OD1   . ASN A 1 215 ? 111.763 108.728 176.463 1.00 79.40  ? 215 ASN A OD1   1 
ATOM   1696 N  ND2   . ASN A 1 215 ? 112.931 110.632 176.269 1.00 73.72  ? 215 ASN A ND2   1 
ATOM   1697 N  N     . GLN A 1 216 ? 113.675 108.053 171.535 1.00 75.87  ? 216 GLN A N     1 
ATOM   1698 C  CA    . GLN A 1 216 ? 113.548 107.651 170.138 1.00 72.44  ? 216 GLN A CA    1 
ATOM   1699 C  C     . GLN A 1 216 ? 113.565 106.136 170.007 1.00 77.46  ? 216 GLN A C     1 
ATOM   1700 O  O     . GLN A 1 216 ? 112.776 105.561 169.248 1.00 82.66  ? 216 GLN A O     1 
ATOM   1701 C  CB    . GLN A 1 216 ? 114.670 108.262 169.299 1.00 73.20  ? 216 GLN A CB    1 
ATOM   1702 C  CG    . GLN A 1 216 ? 114.648 109.770 169.204 1.00 70.05  ? 216 GLN A CG    1 
ATOM   1703 C  CD    . GLN A 1 216 ? 115.588 110.288 168.141 1.00 67.53  ? 216 GLN A CD    1 
ATOM   1704 O  OE1   . GLN A 1 216 ? 115.629 109.767 167.028 1.00 69.71  ? 216 GLN A OE1   1 
ATOM   1705 N  NE2   . GLN A 1 216 ? 116.360 111.311 168.480 1.00 65.45  ? 216 GLN A NE2   1 
ATOM   1706 N  N     . ILE A 1 217 ? 114.460 105.472 170.740 1.00 76.32  ? 217 ILE A N     1 
ATOM   1707 C  CA    . ILE A 1 217 ? 114.511 104.014 170.707 1.00 75.18  ? 217 ILE A CA    1 
ATOM   1708 C  C     . ILE A 1 217 ? 113.231 103.422 171.284 1.00 80.09  ? 217 ILE A C     1 
ATOM   1709 O  O     . ILE A 1 217 ? 112.700 102.431 170.766 1.00 80.38  ? 217 ILE A O     1 
ATOM   1710 C  CB    . ILE A 1 217 ? 115.762 103.513 171.450 1.00 72.66  ? 217 ILE A CB    1 
ATOM   1711 C  CG1   . ILE A 1 217 ? 117.004 103.705 170.578 1.00 76.76  ? 217 ILE A CG1   1 
ATOM   1712 C  CG2   . ILE A 1 217 ? 115.606 102.054 171.847 1.00 71.01  ? 217 ILE A CG2   1 
ATOM   1713 C  CD1   . ILE A 1 217 ? 118.205 102.909 171.034 1.00 86.79  ? 217 ILE A CD1   1 
ATOM   1714 N  N     . LEU A 1 218 ? 112.714 104.020 172.359 1.00 80.66  ? 218 LEU A N     1 
ATOM   1715 C  CA    . LEU A 1 218 ? 111.478 103.534 172.965 1.00 78.80  ? 218 LEU A CA    1 
ATOM   1716 C  C     . LEU A 1 218 ? 110.309 103.630 171.992 1.00 78.68  ? 218 LEU A C     1 
ATOM   1717 O  O     . LEU A 1 218 ? 109.533 102.680 171.841 1.00 79.90  ? 218 LEU A O     1 
ATOM   1718 C  CB    . LEU A 1 218 ? 111.183 104.321 174.242 1.00 77.79  ? 218 LEU A CB    1 
ATOM   1719 C  CG    . LEU A 1 218 ? 109.756 104.275 174.791 1.00 78.37  ? 218 LEU A CG    1 
ATOM   1720 C  CD1   . LEU A 1 218 ? 109.356 102.857 175.166 1.00 82.88  ? 218 LEU A CD1   1 
ATOM   1721 C  CD2   . LEU A 1 218 ? 109.617 105.203 175.983 1.00 78.78  ? 218 LEU A CD2   1 
ATOM   1722 N  N     . LEU A 1 219 ? 110.165 104.776 171.324 1.00 75.66  ? 219 LEU A N     1 
ATOM   1723 C  CA    . LEU A 1 219 ? 109.061 104.950 170.384 1.00 75.35  ? 219 LEU A CA    1 
ATOM   1724 C  C     . LEU A 1 219 ? 109.220 104.052 169.165 1.00 76.67  ? 219 LEU A C     1 
ATOM   1725 O  O     . LEU A 1 219 ? 108.246 103.447 168.703 1.00 81.42  ? 219 LEU A O     1 
ATOM   1726 C  CB    . LEU A 1 219 ? 108.959 106.412 169.952 1.00 71.78  ? 219 LEU A CB    1 
ATOM   1727 C  CG    . LEU A 1 219 ? 108.625 107.450 171.021 1.00 76.05  ? 219 LEU A CG    1 
ATOM   1728 C  CD1   . LEU A 1 219 ? 108.147 108.731 170.367 1.00 63.26  ? 219 LEU A CD1   1 
ATOM   1729 C  CD2   . LEU A 1 219 ? 107.585 106.916 171.982 1.00 72.09  ? 219 LEU A CD2   1 
ATOM   1730 N  N     . SER A 1 220 ? 110.437 103.960 168.624 1.00 76.50  ? 220 SER A N     1 
ATOM   1731 C  CA    . SER A 1 220 ? 110.657 103.155 167.427 1.00 77.09  ? 220 SER A CA    1 
ATOM   1732 C  C     . SER A 1 220 ? 110.389 101.680 167.691 1.00 78.81  ? 220 SER A C     1 
ATOM   1733 O  O     . SER A 1 220 ? 109.801 100.989 166.852 1.00 78.29  ? 220 SER A O     1 
ATOM   1734 C  CB    . SER A 1 220 ? 112.083 103.357 166.916 1.00 77.69  ? 220 SER A CB    1 
ATOM   1735 O  OG    . SER A 1 220 ? 112.339 104.724 166.646 1.00 85.23  ? 220 SER A OG    1 
ATOM   1736 N  N     . GLY A 1 221 ? 110.806 101.182 168.852 1.00 80.81  ? 221 GLY A N     1 
ATOM   1737 C  CA    . GLY A 1 221 ? 110.673 99.774  169.166 1.00 84.22  ? 221 GLY A CA    1 
ATOM   1738 C  C     . GLY A 1 221 ? 109.404 99.420  169.912 1.00 82.65  ? 221 GLY A C     1 
ATOM   1739 O  O     . GLY A 1 221 ? 109.324 98.361  170.540 1.00 86.74  ? 221 GLY A O     1 
ATOM   1740 N  N     . ALA A 1 222 ? 108.404 100.301 169.859 1.00 76.61  ? 222 ALA A N     1 
ATOM   1741 C  CA    . ALA A 1 222 ? 107.141 100.027 170.533 1.00 78.23  ? 222 ALA A CA    1 
ATOM   1742 C  C     . ALA A 1 222 ? 106.335 98.937  169.842 1.00 81.95  ? 222 ALA A C     1 
ATOM   1743 O  O     . ALA A 1 222 ? 105.482 98.316  170.483 1.00 85.24  ? 222 ALA A O     1 
ATOM   1744 C  CB    . ALA A 1 222 ? 106.306 101.303 170.631 1.00 73.17  ? 222 ALA A CB    1 
ATOM   1745 N  N     . TYR A 1 223 ? 106.576 98.694  168.552 1.00 80.35  ? 223 TYR A N     1 
ATOM   1746 C  CA    . TYR A 1 223 ? 105.834 97.661  167.839 1.00 78.39  ? 223 TYR A CA    1 
ATOM   1747 C  C     . TYR A 1 223 ? 106.300 96.257  168.197 1.00 84.39  ? 223 TYR A C     1 
ATOM   1748 O  O     . TYR A 1 223 ? 105.527 95.307  168.044 1.00 90.62  ? 223 TYR A O     1 
ATOM   1749 C  CB    . TYR A 1 223 ? 105.954 97.872  166.328 1.00 76.44  ? 223 TYR A CB    1 
ATOM   1750 C  CG    . TYR A 1 223 ? 107.328 97.564  165.781 1.00 79.31  ? 223 TYR A CG    1 
ATOM   1751 C  CD1   . TYR A 1 223 ? 108.326 98.525  165.784 1.00 75.77  ? 223 TYR A CD1   1 
ATOM   1752 C  CD2   . TYR A 1 223 ? 107.627 96.313  165.261 1.00 86.12  ? 223 TYR A CD2   1 
ATOM   1753 C  CE1   . TYR A 1 223 ? 109.583 98.248  165.288 1.00 79.58  ? 223 TYR A CE1   1 
ATOM   1754 C  CE2   . TYR A 1 223 ? 108.881 96.027  164.766 1.00 88.34  ? 223 TYR A CE2   1 
ATOM   1755 C  CZ    . TYR A 1 223 ? 109.855 96.998  164.781 1.00 85.08  ? 223 TYR A CZ    1 
ATOM   1756 O  OH    . TYR A 1 223 ? 111.106 96.718  164.285 1.00 86.03  ? 223 TYR A OH    1 
ATOM   1757 N  N     . GLN A 1 224 ? 107.545 96.106  168.657 1.00 86.97  ? 224 GLN A N     1 
ATOM   1758 C  CA    . GLN A 1 224 ? 108.081 94.775  168.928 1.00 87.99  ? 224 GLN A CA    1 
ATOM   1759 C  C     . GLN A 1 224 ? 107.295 94.074  170.026 1.00 93.56  ? 224 GLN A C     1 
ATOM   1760 O  O     . GLN A 1 224 ? 107.025 92.871  169.937 1.00 97.92  ? 224 GLN A O     1 
ATOM   1761 C  CB    . GLN A 1 224 ? 109.557 94.874  169.311 1.00 87.57  ? 224 GLN A CB    1 
ATOM   1762 C  CG    . GLN A 1 224 ? 110.508 94.983  168.133 1.00 90.37  ? 224 GLN A CG    1 
ATOM   1763 C  CD    . GLN A 1 224 ? 111.775 95.738  168.483 1.00 98.37  ? 224 GLN A CD    1 
ATOM   1764 O  OE1   . GLN A 1 224 ? 111.834 96.437  169.495 1.00 96.62  ? 224 GLN A OE1   1 
ATOM   1765 N  NE2   . GLN A 1 224 ? 112.797 95.603  167.646 1.00 101.05 ? 224 GLN A NE2   1 
ATOM   1766 N  N     . ARG A 1 225 ? 106.921 94.810  171.073 1.00 92.19  ? 225 ARG A N     1 
ATOM   1767 C  CA    . ARG A 1 225 ? 106.206 94.209  172.191 1.00 92.02  ? 225 ARG A CA    1 
ATOM   1768 C  C     . ARG A 1 225 ? 104.805 93.751  171.810 1.00 94.81  ? 225 ARG A C     1 
ATOM   1769 O  O     . ARG A 1 225 ? 104.240 92.893  172.495 1.00 99.74  ? 225 ARG A O     1 
ATOM   1770 C  CB    . ARG A 1 225 ? 106.143 95.202  173.347 1.00 89.11  ? 225 ARG A CB    1 
ATOM   1771 C  CG    . ARG A 1 225 ? 107.443 95.954  173.547 1.00 89.26  ? 225 ARG A CG    1 
ATOM   1772 C  CD    . ARG A 1 225 ? 107.273 97.061  174.553 1.00 93.87  ? 225 ARG A CD    1 
ATOM   1773 N  NE    . ARG A 1 225 ? 108.462 97.258  175.371 1.00 93.57  ? 225 ARG A NE    1 
ATOM   1774 C  CZ    . ARG A 1 225 ? 109.492 98.017  175.024 1.00 97.61  ? 225 ARG A CZ    1 
ATOM   1775 N  NH1   . ARG A 1 225 ? 109.516 98.664  173.872 1.00 97.18  ? 225 ARG A NH1   1 
ATOM   1776 N  NH2   . ARG A 1 225 ? 110.523 98.131  175.857 1.00 104.03 ? 225 ARG A NH2   1 
ATOM   1777 N  N     . LEU A 1 226 ? 104.238 94.295  170.734 1.00 91.03  ? 226 LEU A N     1 
ATOM   1778 C  CA    . LEU A 1 226 ? 102.906 93.928  170.274 1.00 87.83  ? 226 LEU A CA    1 
ATOM   1779 C  C     . LEU A 1 226 ? 102.948 92.997  169.068 1.00 90.21  ? 226 LEU A C     1 
ATOM   1780 O  O     . LEU A 1 226 ? 101.941 92.847  168.371 1.00 97.22  ? 226 LEU A O     1 
ATOM   1781 C  CB    . LEU A 1 226 ? 102.093 95.180  169.949 1.00 82.97  ? 226 LEU A CB    1 
ATOM   1782 C  CG    . LEU A 1 226 ? 101.175 95.679  171.064 1.00 83.75  ? 226 LEU A CG    1 
ATOM   1783 C  CD1   . LEU A 1 226 ? 101.989 96.312  172.172 1.00 88.55  ? 226 LEU A CD1   1 
ATOM   1784 C  CD2   . LEU A 1 226 ? 100.163 96.664  170.521 1.00 83.59  ? 226 LEU A CD2   1 
ATOM   1785 N  N     . GLN A 1 227 ? 104.092 92.373  168.806 1.00 86.21  ? 227 GLN A N     1 
ATOM   1786 C  CA    . GLN A 1 227 ? 104.254 91.517  167.634 1.00 90.91  ? 227 GLN A CA    1 
ATOM   1787 C  C     . GLN A 1 227 ? 103.479 90.225  167.848 1.00 97.09  ? 227 GLN A C     1 
ATOM   1788 O  O     . GLN A 1 227 ? 103.977 89.278  168.459 1.00 101.70 ? 227 GLN A O     1 
ATOM   1789 C  CB    . GLN A 1 227 ? 105.730 91.234  167.384 1.00 93.22  ? 227 GLN A CB    1 
ATOM   1790 C  CG    . GLN A 1 227 ? 106.445 92.312  166.596 1.00 95.71  ? 227 GLN A CG    1 
ATOM   1791 C  CD    . GLN A 1 227 ? 107.414 91.739  165.583 1.00 98.85  ? 227 GLN A CD    1 
ATOM   1792 O  OE1   . GLN A 1 227 ? 107.397 92.114  164.412 1.00 99.28  ? 227 GLN A OE1   1 
ATOM   1793 N  NE2   . GLN A 1 227 ? 108.261 90.821  166.029 1.00 98.75  ? 227 GLN A NE2   1 
ATOM   1794 N  N     . GLY A 1 228 ? 102.250 90.183  167.343 1.00 98.42  ? 228 GLY A N     1 
ATOM   1795 C  CA    . GLY A 1 228 ? 101.422 89.000  167.465 1.00 97.08  ? 228 GLY A CA    1 
ATOM   1796 C  C     . GLY A 1 228 ? 100.499 89.042  168.663 1.00 97.57  ? 228 GLY A C     1 
ATOM   1797 O  O     . GLY A 1 228 ? 100.268 88.017  169.312 1.00 101.39 ? 228 GLY A O     1 
ATOM   1798 N  N     . ARG A 1 229 ? 99.965  90.224  168.972 1.00 95.22  ? 229 ARG A N     1 
ATOM   1799 C  CA    . ARG A 1 229 ? 99.071  90.368  170.110 1.00 97.43  ? 229 ARG A CA    1 
ATOM   1800 C  C     . ARG A 1 229 ? 97.843  91.223  169.831 1.00 100.89 ? 229 ARG A C     1 
ATOM   1801 O  O     . ARG A 1 229 ? 97.002  91.361  170.724 1.00 105.03 ? 229 ARG A O     1 
ATOM   1802 C  CB    . ARG A 1 229 ? 99.830  90.955  171.310 1.00 97.23  ? 229 ARG A CB    1 
ATOM   1803 C  CG    . ARG A 1 229 ? 100.784 89.977  171.966 1.00 99.44  ? 229 ARG A CG    1 
ATOM   1804 C  CD    . ARG A 1 229 ? 101.448 90.586  173.185 1.00 102.61 ? 229 ARG A CD    1 
ATOM   1805 N  NE    . ARG A 1 229 ? 102.892 90.387  173.178 1.00 103.92 ? 229 ARG A NE    1 
ATOM   1806 C  CZ    . ARG A 1 229 ? 103.492 89.230  173.424 1.00 104.57 ? 229 ARG A CZ    1 
ATOM   1807 N  NH1   . ARG A 1 229 ? 102.800 88.141  173.717 1.00 107.07 ? 229 ARG A NH1   1 
ATOM   1808 N  NH2   . ARG A 1 229 ? 104.819 89.165  173.378 1.00 102.96 ? 229 ARG A NH2   1 
ATOM   1809 N  N     . VAL A 1 230 ? 97.706  91.795  168.640 1.00 100.16 ? 230 VAL A N     1 
ATOM   1810 C  CA    . VAL A 1 230 ? 96.538  92.596  168.298 1.00 98.74  ? 230 VAL A CA    1 
ATOM   1811 C  C     . VAL A 1 230 ? 95.578  91.738  167.489 1.00 102.30 ? 230 VAL A C     1 
ATOM   1812 O  O     . VAL A 1 230 ? 95.980  90.794  166.798 1.00 106.64 ? 230 VAL A O     1 
ATOM   1813 C  CB    . VAL A 1 230 ? 96.923  93.881  167.533 1.00 94.46  ? 230 VAL A CB    1 
ATOM   1814 C  CG1   . VAL A 1 230 ? 98.109  94.557  168.198 1.00 94.08  ? 230 VAL A CG1   1 
ATOM   1815 C  CG2   . VAL A 1 230 ? 97.224  93.578  166.078 1.00 96.31  ? 230 VAL A CG2   1 
ATOM   1816 N  N     . GLN A 1 231 ? 94.299  92.050  167.595 1.00 100.14 ? 231 GLN A N     1 
ATOM   1817 C  CA    . GLN A 1 231 ? 93.278  91.346  166.839 1.00 102.15 ? 231 GLN A CA    1 
ATOM   1818 C  C     . GLN A 1 231 ? 93.023  92.048  165.514 1.00 105.06 ? 231 GLN A C     1 
ATOM   1819 O  O     . GLN A 1 231 ? 93.315  93.238  165.365 1.00 108.23 ? 231 GLN A O     1 
ATOM   1820 C  CB    . GLN A 1 231 ? 91.989  91.262  167.652 1.00 103.16 ? 231 GLN A CB    1 
ATOM   1821 C  CG    . GLN A 1 231 ? 92.131  90.478  168.944 1.00 102.89 ? 231 GLN A CG    1 
ATOM   1822 C  CD    . GLN A 1 231 ? 91.585  89.070  168.832 1.00 103.03 ? 231 GLN A CD    1 
ATOM   1823 O  OE1   . GLN A 1 231 ? 90.703  88.797  168.018 1.00 104.81 ? 231 GLN A OE1   1 
ATOM   1824 N  NE2   . GLN A 1 231 ? 92.108  88.166  169.651 1.00 100.73 ? 231 GLN A NE2   1 
ATOM   1825 N  N     . PRO A 1 232 ? 92.498  91.328  164.518 1.00 102.84 ? 232 PRO A N     1 
ATOM   1826 C  CA    . PRO A 1 232 ? 92.200  91.982  163.231 1.00 101.23 ? 232 PRO A CA    1 
ATOM   1827 C  C     . PRO A 1 232 ? 91.276  93.178  163.366 1.00 100.68 ? 232 PRO A C     1 
ATOM   1828 O  O     . PRO A 1 232 ? 91.454  94.178  162.659 1.00 100.87 ? 232 PRO A O     1 
ATOM   1829 C  CB    . PRO A 1 232 ? 91.554  90.863  162.398 1.00 103.11 ? 232 PRO A CB    1 
ATOM   1830 C  CG    . PRO A 1 232 ? 91.493  89.651  163.275 1.00 106.47 ? 232 PRO A CG    1 
ATOM   1831 C  CD    . PRO A 1 232 ? 92.386  89.864  164.443 1.00 105.28 ? 232 PRO A CD    1 
ATOM   1832 N  N     . GLY A 1 233 ? 90.291  93.106  164.254 1.00 98.05  ? 233 GLY A N     1 
ATOM   1833 C  CA    . GLY A 1 233 ? 89.403  94.218  164.506 1.00 97.11  ? 233 GLY A CA    1 
ATOM   1834 C  C     . GLY A 1 233 ? 89.908  95.230  165.504 1.00 97.59  ? 233 GLY A C     1 
ATOM   1835 O  O     . GLY A 1 233 ? 89.258  96.259  165.714 1.00 99.87  ? 233 GLY A O     1 
ATOM   1836 N  N     . GLU A 1 234 ? 91.055  94.975  166.131 1.00 97.77  ? 234 GLU A N     1 
ATOM   1837 C  CA    . GLU A 1 234 ? 91.602  95.875  167.135 1.00 95.04  ? 234 GLU A CA    1 
ATOM   1838 C  C     . GLU A 1 234 ? 92.566  96.902  166.559 1.00 95.42  ? 234 GLU A C     1 
ATOM   1839 O  O     . GLU A 1 234 ? 93.045  97.762  167.305 1.00 95.50  ? 234 GLU A O     1 
ATOM   1840 C  CB    . GLU A 1 234 ? 92.307  95.075  168.235 1.00 99.79  ? 234 GLU A CB    1 
ATOM   1841 C  CG    . GLU A 1 234 ? 91.438  94.809  169.452 1.00 104.57 ? 234 GLU A CG    1 
ATOM   1842 C  CD    . GLU A 1 234 ? 92.175  94.060  170.543 1.00 111.97 ? 234 GLU A CD    1 
ATOM   1843 O  OE1   . GLU A 1 234 ? 93.368  93.748  170.350 1.00 110.40 ? 234 GLU A OE1   1 
ATOM   1844 O  OE2   . GLU A 1 234 ? 91.560  93.784  171.595 1.00 114.78 ? 234 GLU A OE2   1 
ATOM   1845 N  N     . ILE A 1 235 ? 92.864  96.840  165.263 1.00 96.42  ? 235 ILE A N     1 
ATOM   1846 C  CA    . ILE A 1 235 ? 93.688  97.859  164.616 1.00 90.42  ? 235 ILE A CA    1 
ATOM   1847 C  C     . ILE A 1 235 ? 92.786  99.070  164.405 1.00 88.81  ? 235 ILE A C     1 
ATOM   1848 O  O     . ILE A 1 235 ? 92.030  99.139  163.435 1.00 87.98  ? 235 ILE A O     1 
ATOM   1849 C  CB    . ILE A 1 235 ? 94.294  97.361  163.303 1.00 86.25  ? 235 ILE A CB    1 
ATOM   1850 C  CG1   . ILE A 1 235 ? 95.214  96.169  163.565 1.00 88.37  ? 235 ILE A CG1   1 
ATOM   1851 C  CG2   . ILE A 1 235 ? 95.063  98.476  162.615 1.00 80.75  ? 235 ILE A CG2   1 
ATOM   1852 C  CD1   . ILE A 1 235 ? 95.819  95.578  162.315 1.00 90.33  ? 235 ILE A CD1   1 
ATOM   1853 N  N     . SER A 1 236 ? 92.859  100.030 165.330 1.00 90.95  ? 236 SER A N     1 
ATOM   1854 C  CA    . SER A 1 236 ? 91.891  101.121 165.351 1.00 92.99  ? 236 SER A CA    1 
ATOM   1855 C  C     . SER A 1 236 ? 92.012  102.003 164.115 1.00 90.96  ? 236 SER A C     1 
ATOM   1856 O  O     . SER A 1 236 ? 90.999  102.365 163.506 1.00 89.52  ? 236 SER A O     1 
ATOM   1857 C  CB    . SER A 1 236 ? 92.072  101.949 166.622 1.00 94.20  ? 236 SER A CB    1 
ATOM   1858 O  OG    . SER A 1 236 ? 90.836  102.469 167.073 1.00 101.06 ? 236 SER A OG    1 
ATOM   1859 N  N     . LEU A 1 237 ? 93.235  102.352 163.727 1.00 91.88  ? 237 LEU A N     1 
ATOM   1860 C  CA    . LEU A 1 237 ? 93.434  103.267 162.613 1.00 81.95  ? 237 LEU A CA    1 
ATOM   1861 C  C     . LEU A 1 237 ? 94.867  103.157 162.115 1.00 76.13  ? 237 LEU A C     1 
ATOM   1862 O  O     . LEU A 1 237 ? 95.766  102.757 162.856 1.00 82.37  ? 237 LEU A O     1 
ATOM   1863 C  CB    . LEU A 1 237 ? 93.093  104.708 163.026 1.00 77.14  ? 237 LEU A CB    1 
ATOM   1864 C  CG    . LEU A 1 237 ? 93.921  105.898 162.544 1.00 73.28  ? 237 LEU A CG    1 
ATOM   1865 C  CD1   . LEU A 1 237 ? 93.022  107.086 162.259 1.00 78.15  ? 237 LEU A CD1   1 
ATOM   1866 C  CD2   . LEU A 1 237 ? 94.954  106.261 163.589 1.00 73.06  ? 237 LEU A CD2   1 
ATOM   1867 N  N     . ALA A 1 238 ? 95.063  103.497 160.845 1.00 67.41  ? 238 ALA A N     1 
ATOM   1868 C  CA    . ALA A 1 238 ? 96.384  103.588 160.244 1.00 64.74  ? 238 ALA A CA    1 
ATOM   1869 C  C     . ALA A 1 238 ? 96.581  104.994 159.701 1.00 66.66  ? 238 ALA A C     1 
ATOM   1870 O  O     . ALA A 1 238 ? 95.643  105.600 159.174 1.00 71.58  ? 238 ALA A O     1 
ATOM   1871 C  CB    . ALA A 1 238 ? 96.563  102.562 159.128 1.00 65.94  ? 238 ALA A CB    1 
ATOM   1872 N  N     . VAL A 1 239 ? 97.794  105.517 159.842 1.00 60.93  ? 239 VAL A N     1 
ATOM   1873 C  CA    . VAL A 1 239 ? 98.100  106.884 159.445 1.00 51.44  ? 239 VAL A CA    1 
ATOM   1874 C  C     . VAL A 1 239 ? 99.308  106.869 158.524 1.00 50.82  ? 239 VAL A C     1 
ATOM   1875 O  O     . VAL A 1 239 ? 100.332 106.254 158.843 1.00 58.72  ? 239 VAL A O     1 
ATOM   1876 C  CB    . VAL A 1 239 ? 98.364  107.788 160.662 1.00 47.14  ? 239 VAL A CB    1 
ATOM   1877 C  CG1   . VAL A 1 239 ? 99.025  109.069 160.221 1.00 43.75  ? 239 VAL A CG1   1 
ATOM   1878 C  CG2   . VAL A 1 239 ? 97.071  108.089 161.382 1.00 56.86  ? 239 VAL A CG2   1 
ATOM   1879 N  N     . ALA A 1 240 ? 99.184  107.542 157.385 1.00 47.72  ? 240 ALA A N     1 
ATOM   1880 C  CA    . ALA A 1 240 ? 100.283 107.753 156.453 1.00 48.83  ? 240 ALA A CA    1 
ATOM   1881 C  C     . ALA A 1 240 ? 100.673 109.223 156.524 1.00 48.40  ? 240 ALA A C     1 
ATOM   1882 O  O     . ALA A 1 240 ? 99.888  110.098 156.143 1.00 54.36  ? 240 ALA A O     1 
ATOM   1883 C  CB    . ALA A 1 240 ? 99.887  107.350 155.035 1.00 49.05  ? 240 ALA A CB    1 
ATOM   1884 N  N     . PHE A 1 241 ? 101.873 109.495 157.026 1.00 44.68  ? 241 PHE A N     1 
ATOM   1885 C  CA    . PHE A 1 241 ? 102.388 110.858 157.112 1.00 43.37  ? 241 PHE A CA    1 
ATOM   1886 C  C     . PHE A 1 241 ? 103.129 111.158 155.818 1.00 45.81  ? 241 PHE A C     1 
ATOM   1887 O  O     . PHE A 1 241 ? 104.303 110.812 155.666 1.00 55.13  ? 241 PHE A O     1 
ATOM   1888 C  CB    . PHE A 1 241 ? 103.300 111.022 158.321 1.00 49.96  ? 241 PHE A CB    1 
ATOM   1889 C  CG    . PHE A 1 241 ? 102.586 110.944 159.633 1.00 47.48  ? 241 PHE A CG    1 
ATOM   1890 C  CD1   . PHE A 1 241 ? 101.685 111.919 160.002 1.00 52.52  ? 241 PHE A CD1   1 
ATOM   1891 C  CD2   . PHE A 1 241 ? 102.824 109.899 160.502 1.00 48.26  ? 241 PHE A CD2   1 
ATOM   1892 C  CE1   . PHE A 1 241 ? 101.030 111.851 161.208 1.00 52.74  ? 241 PHE A CE1   1 
ATOM   1893 C  CE2   . PHE A 1 241 ? 102.173 109.828 161.710 1.00 55.28  ? 241 PHE A CE2   1 
ATOM   1894 C  CZ    . PHE A 1 241 ? 101.276 110.807 162.066 1.00 55.39  ? 241 PHE A CZ    1 
ATOM   1895 N  N     . ALA A 1 242 ? 102.443 111.800 154.881 1.00 43.60  ? 242 ALA A N     1 
ATOM   1896 C  CA    . ALA A 1 242 ? 103.021 112.182 153.597 1.00 50.72  ? 242 ALA A CA    1 
ATOM   1897 C  C     . ALA A 1 242 ? 102.961 113.701 153.503 1.00 47.28  ? 242 ALA A C     1 
ATOM   1898 O  O     . ALA A 1 242 ? 101.893 114.274 153.272 1.00 46.89  ? 242 ALA A O     1 
ATOM   1899 C  CB    . ALA A 1 242 ? 102.287 111.513 152.442 1.00 58.44  ? 242 ALA A CB    1 
ATOM   1900 N  N     . ARG A 1 243 ? 104.108 114.344 153.681 1.00 43.59  ? 243 ARG A N     1 
ATOM   1901 C  CA    . ARG A 1 243 ? 104.183 115.797 153.712 1.00 41.17  ? 243 ARG A CA    1 
ATOM   1902 C  C     . ARG A 1 243 ? 104.232 116.362 152.300 1.00 46.24  ? 243 ARG A C     1 
ATOM   1903 O  O     . ARG A 1 243 ? 105.063 115.948 151.487 1.00 52.09  ? 243 ARG A O     1 
ATOM   1904 C  CB    . ARG A 1 243 ? 105.415 116.228 154.503 1.00 36.81  ? 243 ARG A CB    1 
ATOM   1905 C  CG    . ARG A 1 243 ? 105.674 117.712 154.528 1.00 42.46  ? 243 ARG A CG    1 
ATOM   1906 C  CD    . ARG A 1 243 ? 107.085 117.983 155.012 1.00 43.62  ? 243 ARG A CD    1 
ATOM   1907 N  NE    . ARG A 1 243 ? 107.258 119.349 155.487 1.00 52.20  ? 243 ARG A NE    1 
ATOM   1908 C  CZ    . ARG A 1 243 ? 107.337 120.412 154.700 1.00 59.69  ? 243 ARG A CZ    1 
ATOM   1909 N  NH1   . ARG A 1 243 ? 107.267 120.304 153.383 1.00 49.74  ? 243 ARG A NH1   1 
ATOM   1910 N  NH2   . ARG A 1 243 ? 107.490 121.614 155.247 1.00 62.15  ? 243 ARG A NH2   1 
ATOM   1911 N  N     . SER A 1 244 ? 103.338 117.309 152.011 1.00 46.93  ? 244 SER A N     1 
ATOM   1912 C  CA    . SER A 1 244 ? 103.333 118.050 150.749 1.00 46.62  ? 244 SER A CA    1 
ATOM   1913 C  C     . SER A 1 244 ? 103.195 117.106 149.550 1.00 43.65  ? 244 SER A C     1 
ATOM   1914 O  O     . SER A 1 244 ? 104.109 116.934 148.743 1.00 49.58  ? 244 SER A O     1 
ATOM   1915 C  CB    . SER A 1 244 ? 104.588 118.919 150.620 1.00 52.48  ? 244 SER A CB    1 
ATOM   1916 O  OG    . SER A 1 244 ? 105.624 118.209 149.966 1.00 51.57  ? 244 SER A OG    1 
ATOM   1917 N  N     . LEU A 1 245 ? 102.026 116.475 149.478 1.00 42.75  ? 245 LEU A N     1 
ATOM   1918 C  CA    . LEU A 1 245 ? 101.717 115.578 148.374 1.00 45.89  ? 245 LEU A CA    1 
ATOM   1919 C  C     . LEU A 1 245 ? 101.844 116.282 147.027 1.00 47.03  ? 245 LEU A C     1 
ATOM   1920 O  O     . LEU A 1 245 ? 101.799 117.510 146.923 1.00 51.67  ? 245 LEU A O     1 
ATOM   1921 C  CB    . LEU A 1 245 ? 100.300 115.029 148.504 1.00 42.73  ? 245 LEU A CB    1 
ATOM   1922 C  CG    . LEU A 1 245 ? 99.856  114.463 149.843 1.00 46.56  ? 245 LEU A CG    1 
ATOM   1923 C  CD1   . LEU A 1 245 ? 98.356  114.521 149.928 1.00 52.86  ? 245 LEU A CD1   1 
ATOM   1924 C  CD2   . LEU A 1 245 ? 100.327 113.037 149.955 1.00 51.26  ? 245 LEU A CD2   1 
ATOM   1925 N  N     . ARG A 1 246 ? 101.996 115.475 145.986 1.00 42.15  ? 246 ARG A N     1 
ATOM   1926 C  CA    . ARG A 1 246 ? 101.927 115.905 144.600 1.00 40.79  ? 246 ARG A CA    1 
ATOM   1927 C  C     . ARG A 1 246 ? 100.803 115.142 143.910 1.00 47.65  ? 246 ARG A C     1 
ATOM   1928 O  O     . ARG A 1 246 ? 100.067 114.382 144.538 1.00 49.97  ? 246 ARG A O     1 
ATOM   1929 C  CB    . ARG A 1 246 ? 103.262 115.688 143.888 1.00 40.09  ? 246 ARG A CB    1 
ATOM   1930 C  CG    . ARG A 1 246 ? 104.368 116.594 144.376 1.00 40.21  ? 246 ARG A CG    1 
ATOM   1931 C  CD    . ARG A 1 246 ? 104.224 117.984 143.804 1.00 33.95  ? 246 ARG A CD    1 
ATOM   1932 N  NE    . ARG A 1 246 ? 105.357 118.829 144.156 1.00 37.78  ? 246 ARG A NE    1 
ATOM   1933 C  CZ    . ARG A 1 246 ? 105.418 119.579 145.247 1.00 43.74  ? 246 ARG A CZ    1 
ATOM   1934 N  NH1   . ARG A 1 246 ? 104.425 119.609 146.121 1.00 44.61  ? 246 ARG A NH1   1 
ATOM   1935 N  NH2   . ARG A 1 246 ? 106.501 120.318 145.467 1.00 41.59  ? 246 ARG A NH2   1 
ATOM   1936 N  N     . SER A 1 247 ? 100.679 115.337 142.602 1.00 50.76  ? 247 SER A N     1 
ATOM   1937 C  CA    . SER A 1 247 ? 99.597  114.708 141.859 1.00 48.74  ? 247 SER A CA    1 
ATOM   1938 C  C     . SER A 1 247 ? 99.927  113.293 141.404 1.00 51.94  ? 247 SER A C     1 
ATOM   1939 O  O     . SER A 1 247 ? 99.080  112.651 140.774 1.00 53.37  ? 247 SER A O     1 
ATOM   1940 C  CB    . SER A 1 247 ? 99.223  115.566 140.651 1.00 56.43  ? 247 SER A CB    1 
ATOM   1941 O  OG    . SER A 1 247 ? 98.142  116.427 140.959 1.00 65.94  ? 247 SER A OG    1 
ATOM   1942 N  N     . ASP A 1 248 ? 101.123 112.794 141.700 1.00 53.48  ? 248 ASP A N     1 
ATOM   1943 C  CA    . ASP A 1 248 ? 101.488 111.417 141.403 1.00 52.50  ? 248 ASP A CA    1 
ATOM   1944 C  C     . ASP A 1 248 ? 101.944 110.633 142.621 1.00 53.21  ? 248 ASP A C     1 
ATOM   1945 O  O     . ASP A 1 248 ? 101.830 109.406 142.623 1.00 58.96  ? 248 ASP A O     1 
ATOM   1946 C  CB    . ASP A 1 248 ? 102.593 111.371 140.335 1.00 57.11  ? 248 ASP A CB    1 
ATOM   1947 C  CG    . ASP A 1 248 ? 103.971 111.648 140.903 1.00 60.63  ? 248 ASP A CG    1 
ATOM   1948 O  OD1   . ASP A 1 248 ? 104.083 112.484 141.823 1.00 61.20  ? 248 ASP A OD1   1 
ATOM   1949 O  OD2   . ASP A 1 248 ? 104.945 111.032 140.424 1.00 64.47  ? 248 ASP A OD2   1 
ATOM   1950 N  N     . ARG A 1 249 ? 102.458 111.302 143.653 1.00 51.40  ? 249 ARG A N     1 
ATOM   1951 C  CA    . ARG A 1 249 ? 102.877 110.601 144.860 1.00 47.17  ? 249 ARG A CA    1 
ATOM   1952 C  C     . ARG A 1 249 ? 101.692 110.178 145.717 1.00 50.08  ? 249 ARG A C     1 
ATOM   1953 O  O     . ARG A 1 249 ? 101.795 109.199 146.463 1.00 53.93  ? 249 ARG A O     1 
ATOM   1954 C  CB    . ARG A 1 249 ? 103.828 111.479 145.672 1.00 43.34  ? 249 ARG A CB    1 
ATOM   1955 C  CG    . ARG A 1 249 ? 105.010 111.992 144.871 1.00 42.66  ? 249 ARG A CG    1 
ATOM   1956 C  CD    . ARG A 1 249 ? 106.149 112.427 145.767 1.00 37.92  ? 249 ARG A CD    1 
ATOM   1957 N  NE    . ARG A 1 249 ? 105.855 113.666 146.474 1.00 36.44  ? 249 ARG A NE    1 
ATOM   1958 C  CZ    . ARG A 1 249 ? 105.464 113.731 147.738 1.00 42.15  ? 249 ARG A CZ    1 
ATOM   1959 N  NH1   . ARG A 1 249 ? 105.298 112.639 148.466 1.00 45.56  ? 249 ARG A NH1   1 
ATOM   1960 N  NH2   . ARG A 1 249 ? 105.236 114.920 148.287 1.00 44.54  ? 249 ARG A NH2   1 
ATOM   1961 N  N     . LEU A 1 250 ? 100.559 110.878 145.612 1.00 52.94  ? 250 LEU A N     1 
ATOM   1962 C  CA    . LEU A 1 250 ? 99.403  110.539 146.432 1.00 51.42  ? 250 LEU A CA    1 
ATOM   1963 C  C     . LEU A 1 250 ? 98.823  109.174 146.095 1.00 54.42  ? 250 LEU A C     1 
ATOM   1964 O  O     . LEU A 1 250 ? 97.992  108.672 146.857 1.00 56.56  ? 250 LEU A O     1 
ATOM   1965 C  CB    . LEU A 1 250 ? 98.318  111.616 146.309 1.00 47.29  ? 250 LEU A CB    1 
ATOM   1966 C  CG    . LEU A 1 250 ? 97.647  111.936 144.970 1.00 53.49  ? 250 LEU A CG    1 
ATOM   1967 C  CD1   . LEU A 1 250 ? 96.509  110.980 144.660 1.00 57.96  ? 250 LEU A CD1   1 
ATOM   1968 C  CD2   . LEU A 1 250 ? 97.127  113.361 144.982 1.00 58.63  ? 250 LEU A CD2   1 
ATOM   1969 N  N     . TYR A 1 251 ? 99.229  108.568 144.980 1.00 53.86  ? 251 TYR A N     1 
ATOM   1970 C  CA    . TYR A 1 251 ? 98.797  107.216 144.659 1.00 52.80  ? 251 TYR A CA    1 
ATOM   1971 C  C     . TYR A 1 251 ? 99.595  106.154 145.399 1.00 56.42  ? 251 TYR A C     1 
ATOM   1972 O  O     . TYR A 1 251 ? 99.269  104.969 145.281 1.00 64.92  ? 251 TYR A O     1 
ATOM   1973 C  CB    . TYR A 1 251 ? 98.892  106.971 143.152 1.00 49.75  ? 251 TYR A CB    1 
ATOM   1974 C  CG    . TYR A 1 251 ? 97.926  107.802 142.346 1.00 53.23  ? 251 TYR A CG    1 
ATOM   1975 C  CD1   . TYR A 1 251 ? 96.594  107.903 142.716 1.00 58.61  ? 251 TYR A CD1   1 
ATOM   1976 C  CD2   . TYR A 1 251 ? 98.345  108.492 141.222 1.00 57.49  ? 251 TYR A CD2   1 
ATOM   1977 C  CE1   . TYR A 1 251 ? 95.707  108.664 141.986 1.00 64.16  ? 251 TYR A CE1   1 
ATOM   1978 C  CE2   . TYR A 1 251 ? 97.466  109.257 140.485 1.00 65.93  ? 251 TYR A CE2   1 
ATOM   1979 C  CZ    . TYR A 1 251 ? 96.148  109.340 140.871 1.00 67.57  ? 251 TYR A CZ    1 
ATOM   1980 O  OH    . TYR A 1 251 ? 95.269  110.101 140.138 1.00 66.44  ? 251 TYR A OH    1 
ATOM   1981 N  N     . GLN A 1 252 ? 100.628 106.536 146.146 1.00 54.92  ? 252 GLN A N     1 
ATOM   1982 C  CA    . GLN A 1 252 ? 101.327 105.540 146.948 1.00 55.81  ? 252 GLN A CA    1 
ATOM   1983 C  C     . GLN A 1 252 ? 100.550 105.230 148.227 1.00 61.60  ? 252 GLN A C     1 
ATOM   1984 O  O     . GLN A 1 252 ? 100.364 104.048 148.542 1.00 65.16  ? 252 GLN A O     1 
ATOM   1985 C  CB    . GLN A 1 252 ? 102.754 105.986 147.274 1.00 58.10  ? 252 GLN A CB    1 
ATOM   1986 C  CG    . GLN A 1 252 ? 103.474 105.034 148.209 1.00 62.77  ? 252 GLN A CG    1 
ATOM   1987 C  CD    . GLN A 1 252 ? 104.635 105.681 148.929 1.00 69.87  ? 252 GLN A CD    1 
ATOM   1988 O  OE1   . GLN A 1 252 ? 104.966 106.841 148.683 1.00 64.76  ? 252 GLN A OE1   1 
ATOM   1989 N  NE2   . GLN A 1 252 ? 105.263 104.933 149.829 1.00 69.72  ? 252 GLN A NE2   1 
ATOM   1990 N  N     . PRO A 1 253 ? 100.092 106.228 148.999 1.00 58.41  ? 253 PRO A N     1 
ATOM   1991 C  CA    . PRO A 1 253 ? 99.249  105.891 150.159 1.00 56.34  ? 253 PRO A CA    1 
ATOM   1992 C  C     . PRO A 1 253 ? 97.971  105.164 149.784 1.00 59.84  ? 253 PRO A C     1 
ATOM   1993 O  O     . PRO A 1 253 ? 97.548  104.257 150.511 1.00 62.43  ? 253 PRO A O     1 
ATOM   1994 C  CB    . PRO A 1 253 ? 98.962  107.261 150.786 1.00 53.01  ? 253 PRO A CB    1 
ATOM   1995 C  CG    . PRO A 1 253 ? 100.114 108.087 150.392 1.00 51.56  ? 253 PRO A CG    1 
ATOM   1996 C  CD    . PRO A 1 253 ? 100.411 107.668 148.988 1.00 54.60  ? 253 PRO A CD    1 
ATOM   1997 N  N     . LEU A 1 254 ? 97.354  105.526 148.656 1.00 59.64  ? 254 LEU A N     1 
ATOM   1998 C  CA    . LEU A 1 254 ? 96.124  104.865 148.232 1.00 57.42  ? 254 LEU A CA    1 
ATOM   1999 C  C     . LEU A 1 254 ? 96.332  103.364 148.100 1.00 58.48  ? 254 LEU A C     1 
ATOM   2000 O  O     . LEU A 1 254 ? 95.577  102.567 148.670 1.00 68.83  ? 254 LEU A O     1 
ATOM   2001 C  CB    . LEU A 1 254 ? 95.641  105.458 146.910 1.00 53.38  ? 254 LEU A CB    1 
ATOM   2002 C  CG    . LEU A 1 254 ? 94.600  106.569 147.017 1.00 60.57  ? 254 LEU A CG    1 
ATOM   2003 C  CD1   . LEU A 1 254 ? 94.390  107.235 145.673 1.00 66.11  ? 254 LEU A CD1   1 
ATOM   2004 C  CD2   . LEU A 1 254 ? 93.298  106.011 147.543 1.00 64.43  ? 254 LEU A CD2   1 
ATOM   2005 N  N     . TYR A 1 255 ? 97.376  102.961 147.374 1.00 51.88  ? 255 TYR A N     1 
ATOM   2006 C  CA    . TYR A 1 255 ? 97.720  101.547 147.310 1.00 56.84  ? 255 TYR A CA    1 
ATOM   2007 C  C     . TYR A 1 255 ? 97.967  100.989 148.704 1.00 64.12  ? 255 TYR A C     1 
ATOM   2008 O  O     . TYR A 1 255 ? 97.467  99.910  149.044 1.00 71.83  ? 255 TYR A O     1 
ATOM   2009 C  CB    . TYR A 1 255 ? 98.946  101.345 146.422 1.00 57.29  ? 255 TYR A CB    1 
ATOM   2010 C  CG    . TYR A 1 255 ? 99.162  99.915  145.989 1.00 59.89  ? 255 TYR A CG    1 
ATOM   2011 C  CD1   . TYR A 1 255 ? 98.296  99.301  145.098 1.00 59.16  ? 255 TYR A CD1   1 
ATOM   2012 C  CD2   . TYR A 1 255 ? 100.238 99.181  146.466 1.00 60.41  ? 255 TYR A CD2   1 
ATOM   2013 C  CE1   . TYR A 1 255 ? 98.491  97.997  144.700 1.00 63.75  ? 255 TYR A CE1   1 
ATOM   2014 C  CE2   . TYR A 1 255 ? 100.441 97.876  146.071 1.00 60.67  ? 255 TYR A CE2   1 
ATOM   2015 C  CZ    . TYR A 1 255 ? 99.565  97.289  145.189 1.00 67.42  ? 255 TYR A CZ    1 
ATOM   2016 O  OH    . TYR A 1 255 ? 99.763  95.988  144.792 1.00 78.31  ? 255 TYR A OH    1 
ATOM   2017 N  N     . GLU A 1 256 ? 98.691  101.739 149.542 1.00 64.29  ? 256 GLU A N     1 
ATOM   2018 C  CA    . GLU A 1 256 ? 98.948  101.299 150.909 1.00 66.98  ? 256 GLU A CA    1 
ATOM   2019 C  C     . GLU A 1 256 ? 97.653  101.002 151.648 1.00 68.57  ? 256 GLU A C     1 
ATOM   2020 O  O     . GLU A 1 256 ? 97.632  100.156 152.548 1.00 70.19  ? 256 GLU A O     1 
ATOM   2021 C  CB    . GLU A 1 256 ? 99.749  102.358 151.667 1.00 67.81  ? 256 GLU A CB    1 
ATOM   2022 C  CG    . GLU A 1 256 ? 101.187 102.515 151.212 1.00 68.54  ? 256 GLU A CG    1 
ATOM   2023 C  CD    . GLU A 1 256 ? 101.948 103.534 152.039 1.00 74.79  ? 256 GLU A CD    1 
ATOM   2024 O  OE1   . GLU A 1 256 ? 101.455 103.911 153.121 1.00 76.86  ? 256 GLU A OE1   1 
ATOM   2025 O  OE2   . GLU A 1 256 ? 103.034 103.967 151.602 1.00 73.01  ? 256 GLU A OE2   1 
ATOM   2026 N  N     . ALA A 1 257 ? 96.567  101.684 151.285 1.00 62.59  ? 257 ALA A N     1 
ATOM   2027 C  CA    . ALA A 1 257 ? 95.268  101.384 151.868 1.00 61.60  ? 257 ALA A CA    1 
ATOM   2028 C  C     . ALA A 1 257 ? 94.517  100.328 151.071 1.00 68.17  ? 257 ALA A C     1 
ATOM   2029 O  O     . ALA A 1 257 ? 93.852  99.470  151.661 1.00 77.89  ? 257 ALA A O     1 
ATOM   2030 C  CB    . ALA A 1 257 ? 94.427  102.658 151.970 1.00 60.63  ? 257 ALA A CB    1 
ATOM   2031 N  N     . ASN A 1 258 ? 94.633  100.357 149.740 1.00 64.39  ? 258 ASN A N     1 
ATOM   2032 C  CA    . ASN A 1 258 ? 93.856  99.436  148.915 1.00 58.90  ? 258 ASN A CA    1 
ATOM   2033 C  C     . ASN A 1 258 ? 94.237  97.992  149.203 1.00 69.37  ? 258 ASN A C     1 
ATOM   2034 O  O     . ASN A 1 258 ? 93.375  97.106  149.223 1.00 79.30  ? 258 ASN A O     1 
ATOM   2035 C  CB    . ASN A 1 258 ? 94.050  99.758  147.435 1.00 56.77  ? 258 ASN A CB    1 
ATOM   2036 C  CG    . ASN A 1 258 ? 93.042  100.766 146.921 1.00 72.84  ? 258 ASN A CG    1 
ATOM   2037 O  OD1   . ASN A 1 258 ? 92.315  101.384 147.696 1.00 78.06  ? 258 ASN A OD1   1 
ATOM   2038 N  ND2   . ASN A 1 258 ? 92.991  100.933 145.606 1.00 80.00  ? 258 ASN A ND2   1 
ATOM   2039 N  N     . VAL A 1 259 ? 95.526  97.735  149.422 1.00 69.97  ? 259 VAL A N     1 
ATOM   2040 C  CA    . VAL A 1 259 ? 95.951  96.412  149.859 1.00 66.65  ? 259 VAL A CA    1 
ATOM   2041 C  C     . VAL A 1 259 ? 95.507  96.159  151.293 1.00 73.09  ? 259 VAL A C     1 
ATOM   2042 O  O     . VAL A 1 259 ? 95.045  95.061  151.627 1.00 81.84  ? 259 VAL A O     1 
ATOM   2043 C  CB    . VAL A 1 259 ? 97.475  96.266  149.699 1.00 63.27  ? 259 VAL A CB    1 
ATOM   2044 C  CG1   . VAL A 1 259 ? 98.005  95.162  150.594 1.00 66.94  ? 259 VAL A CG1   1 
ATOM   2045 C  CG2   . VAL A 1 259 ? 97.828  95.994  148.250 1.00 67.08  ? 259 VAL A CG2   1 
ATOM   2046 N  N     . MET A 1 260 ? 95.611  97.177  152.154 1.00 73.82  ? 260 MET A N     1 
ATOM   2047 C  CA    . MET A 1 260 ? 95.378  96.979  153.582 1.00 79.38  ? 260 MET A CA    1 
ATOM   2048 C  C     . MET A 1 260 ? 93.984  96.424  153.844 1.00 80.95  ? 260 MET A C     1 
ATOM   2049 O  O     . MET A 1 260 ? 93.830  95.372  154.478 1.00 85.14  ? 260 MET A O     1 
ATOM   2050 C  CB    . MET A 1 260 ? 95.578  98.297  154.330 1.00 78.10  ? 260 MET A CB    1 
ATOM   2051 C  CG    . MET A 1 260 ? 96.288  98.157  155.661 1.00 78.97  ? 260 MET A CG    1 
ATOM   2052 S  SD    . MET A 1 260 ? 96.295  99.675  156.627 1.00 89.30  ? 260 MET A SD    1 
ATOM   2053 C  CE    . MET A 1 260 ? 96.288  99.008  158.288 1.00 88.57  ? 260 MET A CE    1 
ATOM   2054 N  N     . GLN A 1 261 ? 92.957  97.097  153.324 1.00 79.48  ? 261 GLN A N     1 
ATOM   2055 C  CA    . GLN A 1 261 ? 91.595  96.602  153.489 1.00 85.08  ? 261 GLN A CA    1 
ATOM   2056 C  C     . GLN A 1 261 ? 91.437  95.228  152.856 1.00 85.79  ? 261 GLN A C     1 
ATOM   2057 O  O     . GLN A 1 261 ? 90.720  94.370  153.385 1.00 90.42  ? 261 GLN A O     1 
ATOM   2058 C  CB    . GLN A 1 261 ? 90.600  97.593  152.888 1.00 87.30  ? 261 GLN A CB    1 
ATOM   2059 C  CG    . GLN A 1 261 ? 90.698  98.988  153.477 1.00 84.31  ? 261 GLN A CG    1 
ATOM   2060 C  CD    . GLN A 1 261 ? 89.816  99.986  152.758 1.00 94.82  ? 261 GLN A CD    1 
ATOM   2061 O  OE1   . GLN A 1 261 ? 89.137  99.646  151.789 1.00 100.68 ? 261 GLN A OE1   1 
ATOM   2062 N  NE2   . GLN A 1 261 ? 89.821  101.226 153.229 1.00 92.71  ? 261 GLN A NE2   1 
ATOM   2063 N  N     . LEU A 1 262 ? 92.127  94.992  151.736 1.00 82.16  ? 262 LEU A N     1 
ATOM   2064 C  CA    . LEU A 1 262 ? 92.066  93.691  151.080 1.00 84.01  ? 262 LEU A CA    1 
ATOM   2065 C  C     . LEU A 1 262 ? 92.505  92.577  152.019 1.00 90.80  ? 262 LEU A C     1 
ATOM   2066 O  O     . LEU A 1 262 ? 92.041  91.439  151.889 1.00 99.12  ? 262 LEU A O     1 
ATOM   2067 C  CB    . LEU A 1 262 ? 92.926  93.710  149.814 1.00 78.50  ? 262 LEU A CB    1 
ATOM   2068 C  CG    . LEU A 1 262 ? 92.898  92.539  148.824 1.00 77.84  ? 262 LEU A CG    1 
ATOM   2069 C  CD1   . LEU A 1 262 ? 93.831  91.407  149.227 1.00 84.39  ? 262 LEU A CD1   1 
ATOM   2070 C  CD2   . LEU A 1 262 ? 91.479  92.027  148.661 1.00 86.59  ? 262 LEU A CD2   1 
ATOM   2071 N  N     . LEU A 1 263 ? 93.384  92.880  152.972 1.00 90.76  ? 263 LEU A N     1 
ATOM   2072 C  CA    . LEU A 1 263 ? 93.847  91.887  153.928 1.00 90.10  ? 263 LEU A CA    1 
ATOM   2073 C  C     . LEU A 1 263 ? 93.168  92.004  155.284 1.00 95.25  ? 263 LEU A C     1 
ATOM   2074 O  O     . LEU A 1 263 ? 93.508  91.245  156.195 1.00 96.09  ? 263 LEU A O     1 
ATOM   2075 C  CB    . LEU A 1 263 ? 95.366  91.986  154.101 1.00 88.78  ? 263 LEU A CB    1 
ATOM   2076 C  CG    . LEU A 1 263 ? 96.188  91.646  152.858 1.00 88.05  ? 263 LEU A CG    1 
ATOM   2077 C  CD1   . LEU A 1 263 ? 97.674  91.736  153.150 1.00 88.56  ? 263 LEU A CD1   1 
ATOM   2078 C  CD2   . LEU A 1 263 ? 95.823  90.266  152.342 1.00 88.52  ? 263 LEU A CD2   1 
ATOM   2079 N  N     . LEU A 1 264 ? 92.222  92.928  155.444 1.00 95.78  ? 264 LEU A N     1 
ATOM   2080 C  CA    . LEU A 1 264 ? 91.562  93.088  156.734 1.00 95.28  ? 264 LEU A CA    1 
ATOM   2081 C  C     . LEU A 1 264 ? 90.051  92.958  156.599 1.00 98.05  ? 264 LEU A C     1 
ATOM   2082 O  O     . LEU A 1 264 ? 89.375  92.532  157.540 1.00 104.95 ? 264 LEU A O     1 
ATOM   2083 C  CB    . LEU A 1 264 ? 91.931  94.433  157.363 1.00 94.64  ? 264 LEU A CB    1 
ATOM   2084 C  CG    . LEU A 1 264 ? 92.919  94.349  158.529 1.00 94.16  ? 264 LEU A CG    1 
ATOM   2085 C  CD1   . LEU A 1 264 ? 94.310  93.990  158.032 1.00 92.07  ? 264 LEU A CD1   1 
ATOM   2086 C  CD2   . LEU A 1 264 ? 92.949  95.643  159.322 1.00 90.61  ? 264 LEU A CD2   1 
ATOM   2087 N  N     . GLU A 1 265 ? 89.511  93.316  155.436 1.00 96.98  ? 265 GLU A N     1 
ATOM   2088 C  CA    . GLU A 1 265 ? 88.081  93.199  155.179 1.00 99.82  ? 265 GLU A CA    1 
ATOM   2089 C  C     . GLU A 1 265 ? 87.735  91.967  154.353 1.00 101.46 ? 265 GLU A C     1 
ATOM   2090 O  O     . GLU A 1 265 ? 86.828  91.212  154.714 1.00 101.19 ? 265 GLU A O     1 
ATOM   2091 C  CB    . GLU A 1 265 ? 87.567  94.458  154.472 1.00 93.85  ? 265 GLU A CB    1 
ATOM   2092 C  CG    . GLU A 1 265 ? 88.204  95.745  154.957 1.00 94.84  ? 265 GLU A CG    1 
ATOM   2093 C  CD    . GLU A 1 265 ? 87.186  96.835  155.208 1.00 101.31 ? 265 GLU A CD    1 
ATOM   2094 O  OE1   . GLU A 1 265 ? 85.995  96.619  154.900 1.00 103.20 ? 265 GLU A OE1   1 
ATOM   2095 O  OE2   . GLU A 1 265 ? 87.577  97.912  155.704 1.00 102.10 ? 265 GLU A OE2   1 
ATOM   2096 N  N     . GLY A 1 266 ? 88.443  91.746  153.246 1.00 99.95  ? 266 GLY A N     1 
ATOM   2097 C  CA    . GLY A 1 266 ? 88.140  90.626  152.378 1.00 102.31 ? 266 GLY A CA    1 
ATOM   2098 C  C     . GLY A 1 266 ? 88.727  89.298  152.797 1.00 102.26 ? 266 GLY A C     1 
ATOM   2099 O  O     . GLY A 1 266 ? 88.397  88.275  152.189 1.00 105.16 ? 266 GLY A O     1 
ATOM   2100 N  N     . LYS A 1 267 ? 89.588  89.280  153.817 1.00 99.34  ? 267 LYS A N     1 
ATOM   2101 C  CA    . LYS A 1 267 ? 90.202  88.044  154.277 1.00 102.11 ? 267 LYS A CA    1 
ATOM   2102 C  C     . LYS A 1 267 ? 90.181  87.879  155.790 1.00 104.61 ? 267 LYS A C     1 
ATOM   2103 O  O     . LYS A 1 267 ? 90.678  86.863  156.289 1.00 105.85 ? 267 LYS A O     1 
ATOM   2104 C  CB    . LYS A 1 267 ? 91.655  87.947  153.785 1.00 99.15  ? 267 LYS A CB    1 
ATOM   2105 C  CG    . LYS A 1 267 ? 91.822  88.138  152.288 1.00 98.63  ? 267 LYS A CG    1 
ATOM   2106 C  CD    . LYS A 1 267 ? 92.029  86.811  151.584 1.00 100.41 ? 267 LYS A CD    1 
ATOM   2107 C  CE    . LYS A 1 267 ? 91.359  86.805  150.221 1.00 101.82 ? 267 LYS A CE    1 
ATOM   2108 N  NZ    . LYS A 1 267 ? 91.789  85.645  149.394 1.00 97.12  ? 267 LYS A NZ    1 
ATOM   2109 N  N     . LEU A 1 268 ? 89.628  88.837  156.533 1.00 101.10 ? 268 LEU A N     1 
ATOM   2110 C  CA    . LEU A 1 268 ? 89.573  88.745  157.984 1.00 101.73 ? 268 LEU A CA    1 
ATOM   2111 C  C     . LEU A 1 268 ? 88.222  89.106  158.580 1.00 104.58 ? 268 LEU A C     1 
ATOM   2112 O  O     . LEU A 1 268 ? 87.992  88.802  159.756 1.00 108.07 ? 268 LEU A O     1 
ATOM   2113 C  CB    . LEU A 1 268 ? 90.647  89.640  158.621 1.00 104.02 ? 268 LEU A CB    1 
ATOM   2114 C  CG    . LEU A 1 268 ? 92.073  89.097  158.552 1.00 101.47 ? 268 LEU A CG    1 
ATOM   2115 C  CD1   . LEU A 1 268 ? 93.053  90.073  159.173 1.00 97.96  ? 268 LEU A CD1   1 
ATOM   2116 C  CD2   . LEU A 1 268 ? 92.143  87.754  159.244 1.00 101.44 ? 268 LEU A CD2   1 
ATOM   2117 N  N     . GLY A 1 269 ? 87.329  89.738  157.823 1.00 103.40 ? 269 GLY A N     1 
ATOM   2118 C  CA    . GLY A 1 269 ? 86.017  90.075  158.332 1.00 105.57 ? 269 GLY A CA    1 
ATOM   2119 C  C     . GLY A 1 269 ? 85.966  91.261  159.266 1.00 106.41 ? 269 GLY A C     1 
ATOM   2120 O  O     . GLY A 1 269 ? 84.947  91.452  159.939 1.00 109.80 ? 269 GLY A O     1 
ATOM   2121 N  N     . ALA A 1 270 ? 87.027  92.062  159.336 1.00 105.73 ? 270 ALA A N     1 
ATOM   2122 C  CA    . ALA A 1 270 ? 87.003  93.249  160.172 1.00 107.11 ? 270 ALA A CA    1 
ATOM   2123 C  C     . ALA A 1 270 ? 85.977  94.246  159.634 1.00 112.22 ? 270 ALA A C     1 
ATOM   2124 O  O     . ALA A 1 270 ? 85.731  94.302  158.426 1.00 112.41 ? 270 ALA A O     1 
ATOM   2125 C  CB    . ALA A 1 270 ? 88.384  93.896  160.229 1.00 101.46 ? 270 ALA A CB    1 
ATOM   2126 N  N     . PRO A 1 271 ? 85.353  95.035  160.513 1.00 113.60 ? 271 PRO A N     1 
ATOM   2127 C  CA    . PRO A 1 271 ? 84.299  95.950  160.037 1.00 114.94 ? 271 PRO A CA    1 
ATOM   2128 C  C     . PRO A 1 271 ? 84.802  96.992  159.052 1.00 113.81 ? 271 PRO A C     1 
ATOM   2129 O  O     . PRO A 1 271 ? 84.265  97.101  157.942 1.00 114.60 ? 271 PRO A O     1 
ATOM   2130 C  CB    . PRO A 1 271 ? 83.776  96.582  161.336 1.00 114.76 ? 271 PRO A CB    1 
ATOM   2131 C  CG    . PRO A 1 271 ? 84.876  96.399  162.329 1.00 114.73 ? 271 PRO A CG    1 
ATOM   2132 C  CD    . PRO A 1 271 ? 85.537  95.108  161.972 1.00 112.36 ? 271 PRO A CD    1 
ATOM   2133 N  N     . LYS A 1 272 ? 85.820  97.762  159.425 1.00 112.68 ? 272 LYS A N     1 
ATOM   2134 C  CA    . LYS A 1 272 ? 86.366  98.778  158.537 1.00 110.64 ? 272 LYS A CA    1 
ATOM   2135 C  C     . LYS A 1 272 ? 87.766  99.139  159.008 1.00 109.37 ? 272 LYS A C     1 
ATOM   2136 O  O     . LYS A 1 272 ? 88.152  98.852  160.144 1.00 110.20 ? 272 LYS A O     1 
ATOM   2137 C  CB    . LYS A 1 272 ? 85.474  100.024 158.488 1.00 107.68 ? 272 LYS A CB    1 
ATOM   2138 C  CG    . LYS A 1 272 ? 85.500  100.758 157.157 1.00 101.18 ? 272 LYS A CG    1 
ATOM   2139 C  CD    . LYS A 1 272 ? 84.935  102.163 157.291 1.00 104.65 ? 272 LYS A CD    1 
ATOM   2140 C  CE    . LYS A 1 272 ? 85.019  102.920 155.977 1.00 102.05 ? 272 LYS A CE    1 
ATOM   2141 N  NZ    . LYS A 1 272 ? 86.210  103.812 155.925 1.00 95.69  ? 272 LYS A NZ    1 
ATOM   2142 N  N     . VAL A 1 273 ? 88.521  99.772  158.115 1.00 104.46 ? 273 VAL A N     1 
ATOM   2143 C  CA    . VAL A 1 273 ? 89.869  100.243 158.403 1.00 100.42 ? 273 VAL A CA    1 
ATOM   2144 C  C     . VAL A 1 273 ? 89.890  101.750 158.208 1.00 96.32  ? 273 VAL A C     1 
ATOM   2145 O  O     . VAL A 1 273 ? 89.536  102.246 157.132 1.00 98.49  ? 273 VAL A O     1 
ATOM   2146 C  CB    . VAL A 1 273 ? 90.915  99.561  157.505 1.00 98.55  ? 273 VAL A CB    1 
ATOM   2147 C  CG1   . VAL A 1 273 ? 92.306  100.082 157.822 1.00 94.76  ? 273 VAL A CG1   1 
ATOM   2148 C  CG2   . VAL A 1 273 ? 90.848  98.055  157.669 1.00 97.00  ? 273 VAL A CG2   1 
ATOM   2149 N  N     . GLU A 1 274 ? 90.305  102.476 159.242 1.00 91.25  ? 274 GLU A N     1 
ATOM   2150 C  CA    . GLU A 1 274 ? 90.283  103.935 159.212 1.00 91.09  ? 274 GLU A CA    1 
ATOM   2151 C  C     . GLU A 1 274 ? 91.662  104.469 158.825 1.00 86.19  ? 274 GLU A C     1 
ATOM   2152 O  O     . GLU A 1 274 ? 92.338  105.164 159.583 1.00 87.32  ? 274 GLU A O     1 
ATOM   2153 C  CB    . GLU A 1 274 ? 89.823  104.484 160.558 1.00 96.50  ? 274 GLU A CB    1 
ATOM   2154 C  CG    . GLU A 1 274 ? 88.754  103.643 161.238 1.00 101.69 ? 274 GLU A CG    1 
ATOM   2155 C  CD    . GLU A 1 274 ? 87.347  104.035 160.828 1.00 107.00 ? 274 GLU A CD    1 
ATOM   2156 O  OE1   . GLU A 1 274 ? 87.181  104.622 159.740 1.00 101.10 ? 274 GLU A OE1   1 
ATOM   2157 O  OE2   . GLU A 1 274 ? 86.405  103.755 161.598 1.00 115.54 ? 274 GLU A OE2   1 
ATOM   2158 N  N     . PHE A 1 275 ? 92.071  104.123 157.608 1.00 78.15  ? 275 PHE A N     1 
ATOM   2159 C  CA    . PHE A 1 275 ? 93.305  104.653 157.047 1.00 70.40  ? 275 PHE A CA    1 
ATOM   2160 C  C     . PHE A 1 275 ? 93.121  106.132 156.735 1.00 70.04  ? 275 PHE A C     1 
ATOM   2161 O  O     . PHE A 1 275 ? 92.100  106.531 156.168 1.00 74.86  ? 275 PHE A O     1 
ATOM   2162 C  CB    . PHE A 1 275 ? 93.693  103.884 155.785 1.00 66.19  ? 275 PHE A CB    1 
ATOM   2163 C  CG    . PHE A 1 275 ? 95.128  104.065 155.377 1.00 70.12  ? 275 PHE A CG    1 
ATOM   2164 C  CD1   . PHE A 1 275 ? 95.547  105.225 154.750 1.00 70.00  ? 275 PHE A CD1   1 
ATOM   2165 C  CD2   . PHE A 1 275 ? 96.058  103.071 155.618 1.00 74.44  ? 275 PHE A CD2   1 
ATOM   2166 C  CE1   . PHE A 1 275 ? 96.864  105.391 154.375 1.00 66.37  ? 275 PHE A CE1   1 
ATOM   2167 C  CE2   . PHE A 1 275 ? 97.378  103.232 155.245 1.00 74.79  ? 275 PHE A CE2   1 
ATOM   2168 C  CZ    . PHE A 1 275 ? 97.780  104.394 154.622 1.00 69.98  ? 275 PHE A CZ    1 
ATOM   2169 N  N     . GLU A 1 276 ? 94.107  106.945 157.107 1.00 67.58  ? 276 GLU A N     1 
ATOM   2170 C  CA    . GLU A 1 276 ? 94.026  108.375 156.848 1.00 65.70  ? 276 GLU A CA    1 
ATOM   2171 C  C     . GLU A 1 276 ? 95.423  108.928 156.608 1.00 59.46  ? 276 GLU A C     1 
ATOM   2172 O  O     . GLU A 1 276 ? 96.423  108.359 157.050 1.00 65.05  ? 276 GLU A O     1 
ATOM   2173 C  CB    . GLU A 1 276 ? 93.327  109.112 157.996 1.00 67.89  ? 276 GLU A CB    1 
ATOM   2174 C  CG    . GLU A 1 276 ? 94.249  109.702 159.039 1.00 64.10  ? 276 GLU A CG    1 
ATOM   2175 C  CD    . GLU A 1 276 ? 93.529  110.678 159.947 1.00 75.91  ? 276 GLU A CD    1 
ATOM   2176 O  OE1   . GLU A 1 276 ? 92.282  110.632 159.999 1.00 86.51  ? 276 GLU A OE1   1 
ATOM   2177 O  OE2   . GLU A 1 276 ? 94.204  111.489 160.611 1.00 72.07  ? 276 GLU A OE2   1 
ATOM   2178 N  N     . VAL A 1 277 ? 95.473  110.051 155.896 1.00 51.66  ? 277 VAL A N     1 
ATOM   2179 C  CA    . VAL A 1 277 ? 96.715  110.661 155.441 1.00 49.15  ? 277 VAL A CA    1 
ATOM   2180 C  C     . VAL A 1 277 ? 96.853  112.034 156.080 1.00 47.69  ? 277 VAL A C     1 
ATOM   2181 O  O     . VAL A 1 277 ? 95.881  112.793 156.156 1.00 57.10  ? 277 VAL A O     1 
ATOM   2182 C  CB    . VAL A 1 277 ? 96.754  110.772 153.902 1.00 51.62  ? 277 VAL A CB    1 
ATOM   2183 C  CG1   . VAL A 1 277 ? 97.966  111.563 153.445 1.00 46.48  ? 277 VAL A CG1   1 
ATOM   2184 C  CG2   . VAL A 1 277 ? 96.750  109.394 153.274 1.00 58.42  ? 277 VAL A CG2   1 
ATOM   2185 N  N     . HIS A 1 278 ? 98.058  112.347 156.546 1.00 44.60  ? 278 HIS A N     1 
ATOM   2186 C  CA    . HIS A 1 278 ? 98.377  113.666 157.071 1.00 45.06  ? 278 HIS A CA    1 
ATOM   2187 C  C     . HIS A 1 278 ? 99.372  114.355 156.150 1.00 51.90  ? 278 HIS A C     1 
ATOM   2188 O  O     . HIS A 1 278 ? 100.286 113.718 155.621 1.00 59.12  ? 278 HIS A O     1 
ATOM   2189 C  CB    . HIS A 1 278 ? 98.955  113.582 158.483 1.00 44.35  ? 278 HIS A CB    1 
ATOM   2190 C  CG    . HIS A 1 278 ? 97.941  113.251 159.531 1.00 49.56  ? 278 HIS A CG    1 
ATOM   2191 N  ND1   . HIS A 1 278 ? 98.112  113.576 160.859 1.00 50.93  ? 278 HIS A ND1   1 
ATOM   2192 C  CD2   . HIS A 1 278 ? 96.746  112.623 159.448 1.00 50.99  ? 278 HIS A CD2   1 
ATOM   2193 C  CE1   . HIS A 1 278 ? 97.065  113.163 161.549 1.00 52.94  ? 278 HIS A CE1   1 
ATOM   2194 N  NE2   . HIS A 1 278 ? 96.221  112.581 160.717 1.00 56.08  ? 278 HIS A NE2   1 
ATOM   2195 N  N     . THR A 1 279 ? 99.190  115.658 155.956 1.00 48.03  ? 279 THR A N     1 
ATOM   2196 C  CA    . THR A 1 279 ? 100.069 116.423 155.088 1.00 52.11  ? 279 THR A CA    1 
ATOM   2197 C  C     . THR A 1 279 ? 100.120 117.856 155.588 1.00 56.92  ? 279 THR A C     1 
ATOM   2198 O  O     . THR A 1 279 ? 99.230  118.315 156.306 1.00 61.49  ? 279 THR A O     1 
ATOM   2199 C  CB    . THR A 1 279 ? 99.600  116.393 153.632 1.00 54.24  ? 279 THR A CB    1 
ATOM   2200 O  OG1   . THR A 1 279 ? 100.296 117.397 152.888 1.00 63.38  ? 279 THR A OG1   1 
ATOM   2201 C  CG2   . THR A 1 279 ? 98.114  116.661 153.551 1.00 53.12  ? 279 THR A CG2   1 
ATOM   2202 N  N     . LEU A 1 280 ? 101.176 118.564 155.195 1.00 55.12  ? 280 LEU A N     1 
ATOM   2203 C  CA    . LEU A 1 280 ? 101.372 119.943 155.618 1.00 54.55  ? 280 LEU A CA    1 
ATOM   2204 C  C     . LEU A 1 280 ? 101.041 120.956 154.533 1.00 62.95  ? 280 LEU A C     1 
ATOM   2205 O  O     . LEU A 1 280 ? 100.399 121.970 154.820 1.00 68.83  ? 280 LEU A O     1 
ATOM   2206 C  CB    . LEU A 1 280 ? 102.813 120.148 156.085 1.00 50.43  ? 280 LEU A CB    1 
ATOM   2207 C  CG    . LEU A 1 280 ? 102.944 120.412 157.582 1.00 54.33  ? 280 LEU A CG    1 
ATOM   2208 C  CD1   . LEU A 1 280 ? 102.440 119.224 158.357 1.00 55.27  ? 280 LEU A CD1   1 
ATOM   2209 C  CD2   . LEU A 1 280 ? 104.386 120.696 157.942 1.00 58.42  ? 280 LEU A CD2   1 
ATOM   2210 N  N     . ALA A 1 281 ? 101.455 120.709 153.294 1.00 60.05  ? 281 ALA A N     1 
ATOM   2211 C  CA    . ALA A 1 281 ? 101.233 121.635 152.185 1.00 61.59  ? 281 ALA A CA    1 
ATOM   2212 C  C     . ALA A 1 281 ? 100.636 120.877 151.010 1.00 58.98  ? 281 ALA A C     1 
ATOM   2213 O  O     . ALA A 1 281 ? 101.350 120.497 150.073 1.00 59.38  ? 281 ALA A O     1 
ATOM   2214 C  CB    . ALA A 1 281 ? 102.531 122.337 151.785 1.00 62.57  ? 281 ALA A CB    1 
ATOM   2215 N  N     . PRO A 1 282 ? 99.319  120.643 151.019 1.00 62.31  ? 282 PRO A N     1 
ATOM   2216 C  CA    . PRO A 1 282 ? 98.644  119.981 149.898 1.00 66.16  ? 282 PRO A CA    1 
ATOM   2217 C  C     . PRO A 1 282 ? 98.295  120.938 148.761 1.00 73.12  ? 282 PRO A C     1 
ATOM   2218 O  O     . PRO A 1 282 ? 97.183  120.928 148.233 1.00 76.09  ? 282 PRO A O     1 
ATOM   2219 C  CB    . PRO A 1 282 ? 97.385  119.409 150.558 1.00 65.72  ? 282 PRO A CB    1 
ATOM   2220 C  CG    . PRO A 1 282 ? 97.055  120.424 151.593 1.00 69.19  ? 282 PRO A CG    1 
ATOM   2221 C  CD    . PRO A 1 282 ? 98.372  120.986 152.094 1.00 65.16  ? 282 PRO A CD    1 
ATOM   2222 N  N     . GLU A 1 283 ? 99.254  121.777 148.388 1.00 74.43  ? 283 GLU A N     1 
ATOM   2223 C  CA    . GLU A 1 283 ? 99.078  122.724 147.299 1.00 71.02  ? 283 GLU A CA    1 
ATOM   2224 C  C     . GLU A 1 283 ? 99.648  122.152 146.007 1.00 72.54  ? 283 GLU A C     1 
ATOM   2225 O  O     . GLU A 1 283 ? 100.434 121.202 146.011 1.00 71.63  ? 283 GLU A O     1 
ATOM   2226 C  CB    . GLU A 1 283 ? 99.747  124.058 147.629 1.00 73.30  ? 283 GLU A CB    1 
ATOM   2227 C  CG    . GLU A 1 283 ? 101.245 124.081 147.376 1.00 84.81  ? 283 GLU A CG    1 
ATOM   2228 C  CD    . GLU A 1 283 ? 101.855 125.449 147.613 1.00 98.97  ? 283 GLU A CD    1 
ATOM   2229 O  OE1   . GLU A 1 283 ? 102.094 126.176 146.626 1.00 98.65  ? 283 GLU A OE1   1 
ATOM   2230 O  OE2   . GLU A 1 283 ? 102.097 125.796 148.788 1.00 101.76 ? 283 GLU A OE2   1 
ATOM   2231 N  N     . GLY A 1 284 ? 99.241  122.749 144.892 1.00 75.40  ? 284 GLY A N     1 
ATOM   2232 C  CA    . GLY A 1 284 ? 99.641  122.232 143.599 1.00 76.27  ? 284 GLY A CA    1 
ATOM   2233 C  C     . GLY A 1 284 ? 99.093  120.857 143.304 1.00 75.31  ? 284 GLY A C     1 
ATOM   2234 O  O     . GLY A 1 284 ? 99.707  120.099 142.548 1.00 76.00  ? 284 GLY A O     1 
ATOM   2235 N  N     . THR A 1 285 ? 97.949  120.513 143.888 1.00 71.04  ? 285 THR A N     1 
ATOM   2236 C  CA    . THR A 1 285 ? 97.345  119.203 143.699 1.00 65.91  ? 285 THR A CA    1 
ATOM   2237 C  C     . THR A 1 285 ? 95.858  119.306 143.995 1.00 67.32  ? 285 THR A C     1 
ATOM   2238 O  O     . THR A 1 285 ? 95.362  120.337 144.452 1.00 72.05  ? 285 THR A O     1 
ATOM   2239 C  CB    . THR A 1 285 ? 97.994  118.146 144.593 1.00 63.33  ? 285 THR A CB    1 
ATOM   2240 O  OG1   . THR A 1 285 ? 97.178  116.969 144.605 1.00 70.50  ? 285 THR A OG1   1 
ATOM   2241 C  CG2   . THR A 1 285 ? 98.133  118.665 146.009 1.00 62.22  ? 285 THR A CG2   1 
ATOM   2242 N  N     . ASN A 1 286 ? 95.154  118.213 143.725 1.00 67.89  ? 286 ASN A N     1 
ATOM   2243 C  CA    . ASN A 1 286 ? 93.730  118.086 144.001 1.00 70.08  ? 286 ASN A CA    1 
ATOM   2244 C  C     . ASN A 1 286 ? 93.475  116.904 144.924 1.00 73.56  ? 286 ASN A C     1 
ATOM   2245 O  O     . ASN A 1 286 ? 92.494  116.174 144.773 1.00 80.59  ? 286 ASN A O     1 
ATOM   2246 C  CB    . ASN A 1 286 ? 92.936  117.943 142.706 1.00 70.37  ? 286 ASN A CB    1 
ATOM   2247 C  CG    . ASN A 1 286 ? 91.537  118.503 142.818 1.00 75.25  ? 286 ASN A CG    1 
ATOM   2248 O  OD1   . ASN A 1 286 ? 91.130  118.976 143.876 1.00 81.05  ? 286 ASN A OD1   1 
ATOM   2249 N  ND2   . ASN A 1 286 ? 90.790  118.450 141.723 1.00 81.11  ? 286 ASN A ND2   1 
ATOM   2250 N  N     . ALA A 1 287 ? 94.366  116.706 145.900 1.00 69.05  ? 287 ALA A N     1 
ATOM   2251 C  CA    . ALA A 1 287 ? 94.294  115.536 146.768 1.00 67.84  ? 287 ALA A CA    1 
ATOM   2252 C  C     . ALA A 1 287 ? 93.005  115.481 147.574 1.00 75.54  ? 287 ALA A C     1 
ATOM   2253 O  O     . ALA A 1 287 ? 92.623  114.400 148.033 1.00 74.54  ? 287 ALA A O     1 
ATOM   2254 C  CB    . ALA A 1 287 ? 95.497  115.505 147.710 1.00 67.11  ? 287 ALA A CB    1 
ATOM   2255 N  N     . PHE A 1 288 ? 92.326  116.613 147.759 1.00 73.25  ? 288 PHE A N     1 
ATOM   2256 C  CA    . PHE A 1 288 ? 91.059  116.611 148.478 1.00 68.77  ? 288 PHE A CA    1 
ATOM   2257 C  C     . PHE A 1 288 ? 89.937  115.950 147.692 1.00 73.52  ? 288 PHE A C     1 
ATOM   2258 O  O     . PHE A 1 288 ? 88.891  115.649 148.276 1.00 76.19  ? 288 PHE A O     1 
ATOM   2259 C  CB    . PHE A 1 288 ? 90.657  118.041 148.838 1.00 66.46  ? 288 PHE A CB    1 
ATOM   2260 C  CG    . PHE A 1 288 ? 91.354  118.580 150.053 1.00 69.70  ? 288 PHE A CG    1 
ATOM   2261 C  CD1   . PHE A 1 288 ? 90.932  118.228 151.323 1.00 66.80  ? 288 PHE A CD1   1 
ATOM   2262 C  CD2   . PHE A 1 288 ? 92.424  119.448 149.925 1.00 74.07  ? 288 PHE A CD2   1 
ATOM   2263 C  CE1   . PHE A 1 288 ? 91.568  118.726 152.441 1.00 65.98  ? 288 PHE A CE1   1 
ATOM   2264 C  CE2   . PHE A 1 288 ? 93.063  119.949 151.041 1.00 73.04  ? 288 PHE A CE2   1 
ATOM   2265 C  CZ    . PHE A 1 288 ? 92.633  119.588 152.300 1.00 67.71  ? 288 PHE A CZ    1 
ATOM   2266 N  N     . VAL A 1 289 ? 90.123  115.719 146.395 1.00 75.44  ? 289 VAL A N     1 
ATOM   2267 C  CA    . VAL A 1 289 ? 89.095  115.098 145.571 1.00 76.33  ? 289 VAL A CA    1 
ATOM   2268 C  C     . VAL A 1 289 ? 89.509  113.736 145.030 1.00 74.37  ? 289 VAL A C     1 
ATOM   2269 O  O     . VAL A 1 289 ? 88.648  112.848 144.909 1.00 81.93  ? 289 VAL A O     1 
ATOM   2270 C  CB    . VAL A 1 289 ? 88.689  116.037 144.413 1.00 72.94  ? 289 VAL A CB    1 
ATOM   2271 C  CG1   . VAL A 1 289 ? 87.890  115.301 143.347 1.00 70.36  ? 289 VAL A CG1   1 
ATOM   2272 C  CG2   . VAL A 1 289 ? 87.900  117.218 144.949 1.00 72.55  ? 289 VAL A CG2   1 
ATOM   2273 N  N     . THR A 1 290 ? 90.790  113.502 144.756 1.00 66.89  ? 290 THR A N     1 
ATOM   2274 C  CA    . THR A 1 290 ? 91.246  112.203 144.281 1.00 67.82  ? 290 THR A CA    1 
ATOM   2275 C  C     . THR A 1 290 ? 91.511  111.223 145.413 1.00 72.61  ? 290 THR A C     1 
ATOM   2276 O  O     . THR A 1 290 ? 91.996  110.118 145.154 1.00 74.59  ? 290 THR A O     1 
ATOM   2277 C  CB    . THR A 1 290 ? 92.509  112.350 143.427 1.00 68.86  ? 290 THR A CB    1 
ATOM   2278 O  OG1   . THR A 1 290 ? 93.078  111.057 143.192 1.00 68.78  ? 290 THR A OG1   1 
ATOM   2279 C  CG2   . THR A 1 290 ? 93.531  113.212 144.132 1.00 71.28  ? 290 THR A CG2   1 
ATOM   2280 N  N     . TYR A 1 291 ? 91.217  111.601 146.655 1.00 72.63  ? 291 TYR A N     1 
ATOM   2281 C  CA    . TYR A 1 291 ? 91.267  110.686 147.786 1.00 74.47  ? 291 TYR A CA    1 
ATOM   2282 C  C     . TYR A 1 291 ? 89.893  110.149 148.156 1.00 84.15  ? 291 TYR A C     1 
ATOM   2283 O  O     . TYR A 1 291 ? 89.733  109.569 149.234 1.00 83.48  ? 291 TYR A O     1 
ATOM   2284 C  CB    . TYR A 1 291 ? 91.913  111.360 148.995 1.00 64.42  ? 291 TYR A CB    1 
ATOM   2285 C  CG    . TYR A 1 291 ? 93.400  111.130 149.070 1.00 64.40  ? 291 TYR A CG    1 
ATOM   2286 C  CD1   . TYR A 1 291 ? 93.960  109.965 148.571 1.00 65.49  ? 291 TYR A CD1   1 
ATOM   2287 C  CD2   . TYR A 1 291 ? 94.242  112.067 149.640 1.00 61.34  ? 291 TYR A CD2   1 
ATOM   2288 C  CE1   . TYR A 1 291 ? 95.316  109.741 148.636 1.00 60.48  ? 291 TYR A CE1   1 
ATOM   2289 C  CE2   . TYR A 1 291 ? 95.602  111.850 149.709 1.00 61.76  ? 291 TYR A CE2   1 
ATOM   2290 C  CZ    . TYR A 1 291 ? 96.132  110.686 149.206 1.00 61.19  ? 291 TYR A CZ    1 
ATOM   2291 O  OH    . TYR A 1 291 ? 97.485  110.465 149.270 1.00 68.52  ? 291 TYR A OH    1 
ATOM   2292 N  N     . GLU A 1 292 ? 88.899  110.335 147.287 1.00 85.98  ? 292 GLU A N     1 
ATOM   2293 C  CA    . GLU A 1 292 ? 87.600  109.691 147.425 1.00 83.38  ? 292 GLU A CA    1 
ATOM   2294 C  C     . GLU A 1 292 ? 87.539  108.366 146.682 1.00 88.81  ? 292 GLU A C     1 
ATOM   2295 O  O     . GLU A 1 292 ? 86.457  107.945 146.255 1.00 97.09  ? 292 GLU A O     1 
ATOM   2296 C  CB    . GLU A 1 292 ? 86.496  110.628 146.934 1.00 81.41  ? 292 GLU A CB    1 
ATOM   2297 C  CG    . GLU A 1 292 ? 86.326  111.882 147.769 1.00 86.75  ? 292 GLU A CG    1 
ATOM   2298 C  CD    . GLU A 1 292 ? 85.378  112.880 147.135 1.00 97.21  ? 292 GLU A CD    1 
ATOM   2299 O  OE1   . GLU A 1 292 ? 84.980  112.666 145.971 1.00 101.96 ? 292 GLU A OE1   1 
ATOM   2300 O  OE2   . GLU A 1 292 ? 85.030  113.879 147.798 1.00 95.78  ? 292 GLU A OE2   1 
ATOM   2301 N  N     . ALA A 1 293 ? 88.678  107.698 146.517 1.00 79.27  ? 293 ALA A N     1 
ATOM   2302 C  CA    . ALA A 1 293 ? 88.749  106.507 145.690 1.00 79.39  ? 293 ALA A CA    1 
ATOM   2303 C  C     . ALA A 1 293 ? 88.002  105.343 146.333 1.00 85.22  ? 293 ALA A C     1 
ATOM   2304 O  O     . ALA A 1 293 ? 87.680  105.351 147.524 1.00 91.73  ? 293 ALA A O     1 
ATOM   2305 C  CB    . ALA A 1 293 ? 90.205  106.117 145.438 1.00 77.91  ? 293 ALA A CB    1 
ATOM   2306 N  N     . ALA A 1 294 ? 87.727  104.333 145.517 1.00 84.92  ? 294 ALA A N     1 
ATOM   2307 C  CA    . ALA A 1 294 ? 87.032  103.131 145.947 1.00 87.65  ? 294 ALA A CA    1 
ATOM   2308 C  C     . ALA A 1 294 ? 88.047  102.086 146.413 1.00 94.57  ? 294 ALA A C     1 
ATOM   2309 O  O     . ALA A 1 294 ? 89.220  102.384 146.651 1.00 93.02  ? 294 ALA A O     1 
ATOM   2310 C  CB    . ALA A 1 294 ? 86.144  102.605 144.823 1.00 92.22  ? 294 ALA A CB    1 
ATOM   2311 N  N     . SER A 1 295 ? 87.593  100.848 146.560 1.00 97.27  ? 295 SER A N     1 
ATOM   2312 C  CA    . SER A 1 295 ? 88.411  99.760  147.086 1.00 100.89 ? 295 SER A CA    1 
ATOM   2313 C  C     . SER A 1 295 ? 88.114  98.515  146.255 1.00 113.64 ? 295 SER A C     1 
ATOM   2314 O  O     . SER A 1 295 ? 87.601  98.599  145.134 1.00 113.69 ? 295 SER A O     1 
ATOM   2315 C  CB    . SER A 1 295 ? 88.150  99.566  148.587 1.00 103.05 ? 295 SER A CB    1 
ATOM   2316 O  OG    . SER A 1 295 ? 88.129  100.811 149.262 1.00 93.52  ? 295 SER A OG    1 
ATOM   2317 N  N     . LEU A 1 296 ? 88.462  97.343  146.793 1.00 120.48 ? 296 LEU A N     1 
ATOM   2318 C  CA    . LEU A 1 296 ? 88.239  96.062  146.125 1.00 118.56 ? 296 LEU A CA    1 
ATOM   2319 C  C     . LEU A 1 296 ? 86.776  95.843  145.748 1.00 125.29 ? 296 LEU A C     1 
ATOM   2320 O  O     . LEU A 1 296 ? 86.443  94.847  145.098 1.00 125.09 ? 296 LEU A O     1 
ATOM   2321 C  CB    . LEU A 1 296 ? 88.717  94.912  147.015 1.00 110.31 ? 296 LEU A CB    1 
ATOM   2322 C  CG    . LEU A 1 296 ? 87.994  94.749  148.355 1.00 111.75 ? 296 LEU A CG    1 
ATOM   2323 C  CD1   . LEU A 1 296 ? 87.667  93.287  148.610 1.00 114.15 ? 296 LEU A CD1   1 
ATOM   2324 C  CD2   . LEU A 1 296 ? 88.822  95.318  149.495 1.00 101.33 ? 296 LEU A CD2   1 
ATOM   2325 N  N     . TYR A 1 297 ? 85.892  96.723  146.219 1.00 128.16 ? 297 TYR A N     1 
ATOM   2326 C  CA    . TYR A 1 297 ? 84.512  96.930  145.780 1.00 131.72 ? 297 TYR A CA    1 
ATOM   2327 C  C     . TYR A 1 297 ? 83.590  95.751  146.070 1.00 138.83 ? 297 TYR A C     1 
ATOM   2328 O  O     . TYR A 1 297 ? 82.381  95.867  145.835 1.00 142.02 ? 297 TYR A O     1 
ATOM   2329 C  CB    . TYR A 1 297 ? 84.424  97.328  144.291 1.00 126.21 ? 297 TYR A CB    1 
ATOM   2330 C  CG    . TYR A 1 297 ? 84.482  96.215  143.256 1.00 127.15 ? 297 TYR A CG    1 
ATOM   2331 C  CD1   . TYR A 1 297 ? 83.361  95.458  142.948 1.00 131.14 ? 297 TYR A CD1   1 
ATOM   2332 C  CD2   . TYR A 1 297 ? 85.647  95.968  142.542 1.00 123.62 ? 297 TYR A CD2   1 
ATOM   2333 C  CE1   . TYR A 1 297 ? 83.410  94.457  141.997 1.00 127.26 ? 297 TYR A CE1   1 
ATOM   2334 C  CE2   . TYR A 1 297 ? 85.705  94.966  141.592 1.00 121.66 ? 297 TYR A CE2   1 
ATOM   2335 C  CZ    . TYR A 1 297 ? 84.583  94.217  141.321 1.00 120.55 ? 297 TYR A CZ    1 
ATOM   2336 O  OH    . TYR A 1 297 ? 84.636  93.224  140.371 1.00 115.94 ? 297 TYR A OH    1 
ATOM   2337 N  N     . GLY A 1 298 ? 84.102  94.638  146.594 1.00 137.76 ? 298 GLY A N     1 
ATOM   2338 C  CA    . GLY A 1 298 ? 83.264  93.555  147.077 1.00 143.28 ? 298 GLY A CA    1 
ATOM   2339 C  C     . GLY A 1 298 ? 82.250  93.017  146.087 1.00 147.79 ? 298 GLY A C     1 
ATOM   2340 O  O     . GLY A 1 298 ? 82.610  92.367  145.101 1.00 146.51 ? 298 GLY A O     1 
ATOM   2341 N  N     . LEU A 1 299 ? 80.973  93.284  146.350 1.00 149.29 ? 299 LEU A N     1 
ATOM   2342 C  CA    . LEU A 1 299 ? 79.883  92.801  145.513 1.00 147.66 ? 299 LEU A CA    1 
ATOM   2343 C  C     . LEU A 1 299 ? 79.838  93.603  144.213 1.00 146.58 ? 299 LEU A C     1 
ATOM   2344 O  O     . LEU A 1 299 ? 80.719  94.417  143.925 1.00 145.92 ? 299 LEU A O     1 
ATOM   2345 C  CB    . LEU A 1 299 ? 78.562  92.869  146.277 1.00 147.77 ? 299 LEU A CB    1 
ATOM   2346 C  CG    . LEU A 1 299 ? 78.331  91.832  147.381 1.00 147.63 ? 299 LEU A CG    1 
ATOM   2347 C  CD1   . LEU A 1 299 ? 78.865  90.467  146.969 1.00 142.04 ? 299 LEU A CD1   1 
ATOM   2348 C  CD2   . LEU A 1 299 ? 78.947  92.277  148.701 1.00 149.37 ? 299 LEU A CD2   1 
ATOM   2349 N  N     . ALA A 1 300 ? 78.798  93.378  143.407 1.00 149.16 ? 300 ALA A N     1 
ATOM   2350 C  CA    . ALA A 1 300 ? 78.709  94.023  142.099 1.00 151.19 ? 300 ALA A CA    1 
ATOM   2351 C  C     . ALA A 1 300 ? 78.656  95.541  142.233 1.00 155.57 ? 300 ALA A C     1 
ATOM   2352 O  O     . ALA A 1 300 ? 79.562  96.251  141.781 1.00 153.89 ? 300 ALA A O     1 
ATOM   2353 C  CB    . ALA A 1 300 ? 77.487  93.501  141.342 1.00 150.01 ? 300 ALA A CB    1 
ATOM   2354 N  N     . GLU A 1 301 ? 77.601  96.058  142.857 1.00 159.70 ? 301 GLU A N     1 
ATOM   2355 C  CA    . GLU A 1 301 ? 77.456  97.495  143.046 1.00 158.96 ? 301 GLU A CA    1 
ATOM   2356 C  C     . GLU A 1 301 ? 76.456  97.742  144.166 1.00 160.69 ? 301 GLU A C     1 
ATOM   2357 O  O     . GLU A 1 301 ? 75.768  96.829  144.628 1.00 161.02 ? 301 GLU A O     1 
ATOM   2358 C  CB    . GLU A 1 301 ? 77.017  98.192  141.753 1.00 158.56 ? 301 GLU A CB    1 
ATOM   2359 C  CG    . GLU A 1 301 ? 75.585  97.900  141.340 1.00 157.65 ? 301 GLU A CG    1 
ATOM   2360 C  CD    . GLU A 1 301 ? 75.170  98.672  140.103 1.00 151.84 ? 301 GLU A CD    1 
ATOM   2361 O  OE1   . GLU A 1 301 ? 76.013  99.410  139.551 1.00 145.16 ? 301 GLU A OE1   1 
ATOM   2362 O  OE2   . GLU A 1 301 ? 74.002  98.539  139.682 1.00 150.43 ? 301 GLU A OE2   1 
ATOM   2363 N  N     . GLY A 1 302 ? 76.385  99.003  144.597 1.00 159.18 ? 302 GLY A N     1 
ATOM   2364 C  CA    . GLY A 1 302 ? 75.495  99.412  145.662 1.00 159.53 ? 302 GLY A CA    1 
ATOM   2365 C  C     . GLY A 1 302 ? 76.262  100.013 146.828 1.00 158.25 ? 302 GLY A C     1 
ATOM   2366 O  O     . GLY A 1 302 ? 77.339  100.593 146.652 1.00 156.04 ? 302 GLY A O     1 
ATOM   2367 N  N     . ARG A 1 303 ? 75.689  99.866  148.022 1.00 158.26 ? 303 ARG A N     1 
ATOM   2368 C  CA    . ARG A 1 303 ? 76.302  100.343 149.256 1.00 158.55 ? 303 ARG A CA    1 
ATOM   2369 C  C     . ARG A 1 303 ? 76.692  99.179  150.162 1.00 159.85 ? 303 ARG A C     1 
ATOM   2370 O  O     . ARG A 1 303 ? 76.699  99.310  151.387 1.00 164.84 ? 303 ARG A O     1 
ATOM   2371 C  CB    . ARG A 1 303 ? 75.364  101.303 149.989 1.00 158.71 ? 303 ARG A CB    1 
ATOM   2372 C  CG    . ARG A 1 303 ? 76.069  102.453 150.689 1.00 156.38 ? 303 ARG A CG    1 
ATOM   2373 C  CD    . ARG A 1 303 ? 75.084  103.313 151.463 1.00 159.34 ? 303 ARG A CD    1 
ATOM   2374 N  NE    . ARG A 1 303 ? 74.396  102.555 152.502 1.00 162.49 ? 303 ARG A NE    1 
ATOM   2375 C  CZ    . ARG A 1 303 ? 73.096  102.294 152.503 1.00 161.95 ? 303 ARG A CZ    1 
ATOM   2376 N  NH1   . ARG A 1 303 ? 72.306  102.715 151.530 1.00 161.39 ? 303 ARG A NH1   1 
ATOM   2377 N  NH2   . ARG A 1 303 ? 72.577  101.592 153.507 1.00 159.14 ? 303 ARG A NH2   1 
ATOM   2378 N  N     . SER A 1 304 ? 77.021  98.033  149.565 1.00 156.62 ? 304 SER A N     1 
ATOM   2379 C  CA    . SER A 1 304 ? 77.306  96.835  150.347 1.00 155.77 ? 304 SER A CA    1 
ATOM   2380 C  C     . SER A 1 304 ? 78.716  96.867  150.928 1.00 151.94 ? 304 SER A C     1 
ATOM   2381 O  O     . SER A 1 304 ? 78.897  96.853  152.150 1.00 148.41 ? 304 SER A O     1 
ATOM   2382 C  CB    . SER A 1 304 ? 77.109  95.589  149.481 1.00 152.07 ? 304 SER A CB    1 
ATOM   2383 O  OG    . SER A 1 304 ? 78.161  95.452  148.542 1.00 148.89 ? 304 SER A OG    1 
ATOM   2384 N  N     . ALA A 1 305 ? 79.728  96.914  150.064 1.00 148.42 ? 305 ALA A N     1 
ATOM   2385 C  CA    . ALA A 1 305 ? 81.119  96.850  150.497 1.00 140.32 ? 305 ALA A CA    1 
ATOM   2386 C  C     . ALA A 1 305 ? 81.958  97.882  149.759 1.00 133.57 ? 305 ALA A C     1 
ATOM   2387 O  O     . ALA A 1 305 ? 83.074  97.597  149.310 1.00 130.72 ? 305 ALA A O     1 
ATOM   2388 C  CB    . ALA A 1 305 ? 81.694  95.448  150.300 1.00 136.82 ? 305 ALA A CB    1 
ATOM   2389 N  N     . VAL A 1 306 ? 81.436  99.097  149.621 1.00 125.52 ? 306 VAL A N     1 
ATOM   2390 C  CA    . VAL A 1 306 ? 82.145  100.193 148.974 1.00 113.75 ? 306 VAL A CA    1 
ATOM   2391 C  C     . VAL A 1 306 ? 82.308  101.328 149.976 1.00 107.46 ? 306 VAL A C     1 
ATOM   2392 O  O     . VAL A 1 306 ? 81.383  101.644 150.735 1.00 111.90 ? 306 VAL A O     1 
ATOM   2393 C  CB    . VAL A 1 306 ? 81.427  100.659 147.688 1.00 112.18 ? 306 VAL A CB    1 
ATOM   2394 C  CG1   . VAL A 1 306 ? 80.188  101.488 148.000 1.00 118.38 ? 306 VAL A CG1   1 
ATOM   2395 C  CG2   . VAL A 1 306 ? 82.384  101.434 146.798 1.00 108.54 ? 306 VAL A CG2   1 
ATOM   2396 N  N     . HIS A 1 307 ? 83.505  101.904 150.013 1.00 103.58 ? 307 HIS A N     1 
ATOM   2397 C  CA    . HIS A 1 307 ? 83.820  102.998 150.923 1.00 97.85  ? 307 HIS A CA    1 
ATOM   2398 C  C     . HIS A 1 307 ? 85.115  103.644 150.450 1.00 96.33  ? 307 HIS A C     1 
ATOM   2399 O  O     . HIS A 1 307 ? 85.832  103.097 149.609 1.00 99.85  ? 307 HIS A O     1 
ATOM   2400 C  CB    . HIS A 1 307 ? 83.945  102.516 152.370 1.00 95.89  ? 307 HIS A CB    1 
ATOM   2401 C  CG    . HIS A 1 307 ? 84.761  101.271 152.524 1.00 100.13 ? 307 HIS A CG    1 
ATOM   2402 N  ND1   . HIS A 1 307 ? 84.196  100.019 152.635 1.00 107.31 ? 307 HIS A ND1   1 
ATOM   2403 C  CD2   . HIS A 1 307 ? 86.100  101.086 152.588 1.00 98.41  ? 307 HIS A CD2   1 
ATOM   2404 C  CE1   . HIS A 1 307 ? 85.152  99.116  152.759 1.00 107.20 ? 307 HIS A CE1   1 
ATOM   2405 N  NE2   . HIS A 1 307 ? 86.317  99.737  152.733 1.00 101.86 ? 307 HIS A NE2   1 
ATOM   2406 N  N     . ARG A 1 308 ? 85.402  104.819 151.000 1.00 90.36  ? 308 ARG A N     1 
ATOM   2407 C  CA    . ARG A 1 308 ? 86.615  105.535 150.636 1.00 81.50  ? 308 ARG A CA    1 
ATOM   2408 C  C     . ARG A 1 308 ? 87.845  104.776 151.114 1.00 84.42  ? 308 ARG A C     1 
ATOM   2409 O  O     . ARG A 1 308 ? 87.898  104.300 152.252 1.00 86.26  ? 308 ARG A O     1 
ATOM   2410 C  CB    . ARG A 1 308 ? 86.601  106.940 151.235 1.00 77.91  ? 308 ARG A CB    1 
ATOM   2411 C  CG    . ARG A 1 308 ? 85.387  107.767 150.851 1.00 83.46  ? 308 ARG A CG    1 
ATOM   2412 C  CD    . ARG A 1 308 ? 85.431  109.143 151.491 1.00 86.46  ? 308 ARG A CD    1 
ATOM   2413 N  NE    . ARG A 1 308 ? 86.497  109.966 150.933 1.00 89.45  ? 308 ARG A NE    1 
ATOM   2414 C  CZ    . ARG A 1 308 ? 87.268  110.776 151.645 1.00 87.79  ? 308 ARG A CZ    1 
ATOM   2415 N  NH1   . ARG A 1 308 ? 87.120  110.899 152.954 1.00 85.57  ? 308 ARG A NH1   1 
ATOM   2416 N  NH2   . ARG A 1 308 ? 88.212  111.481 151.028 1.00 84.84  ? 308 ARG A NH2   1 
ATOM   2417 N  N     . ALA A 1 309 ? 88.838  104.656 150.231 1.00 86.57  ? 309 ALA A N     1 
ATOM   2418 C  CA    . ALA A 1 309 ? 90.088  104.007 150.612 1.00 81.60  ? 309 ALA A CA    1 
ATOM   2419 C  C     . ALA A 1 309 ? 90.813  104.803 151.689 1.00 76.73  ? 309 ALA A C     1 
ATOM   2420 O  O     . ALA A 1 309 ? 91.359  104.225 152.636 1.00 81.27  ? 309 ALA A O     1 
ATOM   2421 C  CB    . ALA A 1 309 ? 90.981  103.821 149.388 1.00 76.09  ? 309 ALA A CB    1 
ATOM   2422 N  N     . ILE A 1 310 ? 90.829  106.126 151.561 1.00 72.39  ? 310 ILE A N     1 
ATOM   2423 C  CA    . ILE A 1 310 ? 91.399  107.020 152.561 1.00 68.13  ? 310 ILE A CA    1 
ATOM   2424 C  C     . ILE A 1 310 ? 90.242  107.716 153.262 1.00 77.94  ? 310 ILE A C     1 
ATOM   2425 O  O     . ILE A 1 310 ? 89.430  108.387 152.613 1.00 80.03  ? 310 ILE A O     1 
ATOM   2426 C  CB    . ILE A 1 310 ? 92.357  108.039 151.931 1.00 64.88  ? 310 ILE A CB    1 
ATOM   2427 C  CG1   . ILE A 1 310 ? 93.332  107.338 150.987 1.00 63.79  ? 310 ILE A CG1   1 
ATOM   2428 C  CG2   . ILE A 1 310 ? 93.111  108.795 153.006 1.00 64.35  ? 310 ILE A CG2   1 
ATOM   2429 C  CD1   . ILE A 1 310 ? 94.328  106.457 151.689 1.00 67.10  ? 310 ILE A CD1   1 
ATOM   2430 N  N     . ARG A 1 311 ? 90.162  107.551 154.584 1.00 79.16  ? 311 ARG A N     1 
ATOM   2431 C  CA    . ARG A 1 311 ? 89.033  108.104 155.325 1.00 77.29  ? 311 ARG A CA    1 
ATOM   2432 C  C     . ARG A 1 311 ? 89.010  109.624 155.259 1.00 76.53  ? 311 ARG A C     1 
ATOM   2433 O  O     . ARG A 1 311 ? 87.949  110.227 155.059 1.00 78.03  ? 311 ARG A O     1 
ATOM   2434 C  CB    . ARG A 1 311 ? 89.076  107.640 156.779 1.00 83.83  ? 311 ARG A CB    1 
ATOM   2435 C  CG    . ARG A 1 311 ? 87.834  108.014 157.569 1.00 88.51  ? 311 ARG A CG    1 
ATOM   2436 C  CD    . ARG A 1 311 ? 87.971  107.640 159.031 1.00 93.10  ? 311 ARG A CD    1 
ATOM   2437 N  NE    . ARG A 1 311 ? 89.117  108.292 159.653 1.00 91.80  ? 311 ARG A NE    1 
ATOM   2438 C  CZ    . ARG A 1 311 ? 89.041  109.387 160.395 1.00 91.49  ? 311 ARG A CZ    1 
ATOM   2439 N  NH1   . ARG A 1 311 ? 87.883  109.981 160.633 1.00 88.78  ? 311 ARG A NH1   1 
ATOM   2440 N  NH2   . ARG A 1 311 ? 90.154  109.900 160.911 1.00 92.31  ? 311 ARG A NH2   1 
ATOM   2441 N  N     . GLU A 1 312 ? 90.166  110.262 155.421 1.00 74.98  ? 312 GLU A N     1 
ATOM   2442 C  CA    . GLU A 1 312 ? 90.227  111.714 155.458 1.00 75.06  ? 312 GLU A CA    1 
ATOM   2443 C  C     . GLU A 1 312 ? 91.669  112.157 155.269 1.00 65.82  ? 312 GLU A C     1 
ATOM   2444 O  O     . GLU A 1 312 ? 92.603  111.457 155.665 1.00 67.56  ? 312 GLU A O     1 
ATOM   2445 C  CB    . GLU A 1 312 ? 89.668  112.258 156.780 1.00 82.19  ? 312 GLU A CB    1 
ATOM   2446 C  CG    . GLU A 1 312 ? 89.636  113.774 156.888 1.00 82.36  ? 312 GLU A CG    1 
ATOM   2447 C  CD    . GLU A 1 312 ? 88.894  114.255 158.118 1.00 96.33  ? 312 GLU A CD    1 
ATOM   2448 O  OE1   . GLU A 1 312 ? 87.683  113.975 158.232 1.00 100.30 ? 312 GLU A OE1   1 
ATOM   2449 O  OE2   . GLU A 1 312 ? 89.525  114.909 158.976 1.00 97.99  ? 312 GLU A OE2   1 
ATOM   2450 N  N     . LEU A 1 313 ? 91.834  113.323 154.654 1.00 59.56  ? 313 LEU A N     1 
ATOM   2451 C  CA    . LEU A 1 313 ? 93.123  113.991 154.557 1.00 51.72  ? 313 LEU A CA    1 
ATOM   2452 C  C     . LEU A 1 313 ? 93.159  115.122 155.573 1.00 52.48  ? 313 LEU A C     1 
ATOM   2453 O  O     . LEU A 1 313 ? 92.230  115.933 155.637 1.00 61.95  ? 313 LEU A O     1 
ATOM   2454 C  CB    . LEU A 1 313 ? 93.352  114.536 153.147 1.00 51.19  ? 313 LEU A CB    1 
ATOM   2455 C  CG    . LEU A 1 313 ? 94.686  115.231 152.873 1.00 47.41  ? 313 LEU A CG    1 
ATOM   2456 C  CD1   . LEU A 1 313 ? 95.208  114.833 151.519 1.00 46.45  ? 313 LEU A CD1   1 
ATOM   2457 C  CD2   . LEU A 1 313 ? 94.530  116.731 152.942 1.00 56.70  ? 313 LEU A CD2   1 
ATOM   2458 N  N     . TYR A 1 314 ? 94.225  115.176 156.364 1.00 51.78  ? 314 TYR A N     1 
ATOM   2459 C  CA    . TYR A 1 314 ? 94.362  116.182 157.404 1.00 54.65  ? 314 TYR A CA    1 
ATOM   2460 C  C     . TYR A 1 314 ? 95.525  117.110 157.087 1.00 58.39  ? 314 TYR A C     1 
ATOM   2461 O  O     . TYR A 1 314 ? 96.533  116.687 156.515 1.00 63.93  ? 314 TYR A O     1 
ATOM   2462 C  CB    . TYR A 1 314 ? 94.573  115.539 158.774 1.00 57.23  ? 314 TYR A CB    1 
ATOM   2463 C  CG    . TYR A 1 314 ? 94.367  116.499 159.921 1.00 58.75  ? 314 TYR A CG    1 
ATOM   2464 C  CD1   . TYR A 1 314 ? 93.243  117.308 159.977 1.00 65.82  ? 314 TYR A CD1   1 
ATOM   2465 C  CD2   . TYR A 1 314 ? 95.301  116.605 160.941 1.00 58.49  ? 314 TYR A CD2   1 
ATOM   2466 C  CE1   . TYR A 1 314 ? 93.051  118.190 161.019 1.00 70.84  ? 314 TYR A CE1   1 
ATOM   2467 C  CE2   . TYR A 1 314 ? 95.117  117.484 161.986 1.00 65.97  ? 314 TYR A CE2   1 
ATOM   2468 C  CZ    . TYR A 1 314 ? 93.990  118.274 162.020 1.00 74.25  ? 314 TYR A CZ    1 
ATOM   2469 O  OH    . TYR A 1 314 ? 93.801  119.153 163.061 1.00 80.89  ? 314 TYR A OH    1 
ATOM   2470 N  N     . VAL A 1 315 ? 95.361  118.381 157.439 1.00 55.81  ? 315 VAL A N     1 
ATOM   2471 C  CA    . VAL A 1 315 ? 96.420  119.380 157.329 1.00 57.16  ? 315 VAL A CA    1 
ATOM   2472 C  C     . VAL A 1 315 ? 96.506  120.109 158.663 1.00 61.48  ? 315 VAL A C     1 
ATOM   2473 O  O     . VAL A 1 315 ? 95.772  121.084 158.880 1.00 71.43  ? 315 VAL A O     1 
ATOM   2474 C  CB    . VAL A 1 315 ? 96.159  120.361 156.176 1.00 59.34  ? 315 VAL A CB    1 
ATOM   2475 C  CG1   . VAL A 1 315 ? 97.323  121.327 156.030 1.00 59.38  ? 315 VAL A CG1   1 
ATOM   2476 C  CG2   . VAL A 1 315 ? 95.918  119.610 154.882 1.00 56.66  ? 315 VAL A CG2   1 
ATOM   2477 N  N     . PRO A 1 316 ? 97.366  119.676 159.580 1.00 55.85  ? 316 PRO A N     1 
ATOM   2478 C  CA    . PRO A 1 316 ? 97.397  120.276 160.915 1.00 61.21  ? 316 PRO A CA    1 
ATOM   2479 C  C     . PRO A 1 316 ? 97.847  121.723 160.854 1.00 64.40  ? 316 PRO A C     1 
ATOM   2480 O  O     . PRO A 1 316 ? 98.970  122.017 160.417 1.00 69.47  ? 316 PRO A O     1 
ATOM   2481 C  CB    . PRO A 1 316 ? 98.415  119.409 161.673 1.00 63.21  ? 316 PRO A CB    1 
ATOM   2482 C  CG    . PRO A 1 316 ? 98.612  118.192 160.829 1.00 61.30  ? 316 PRO A CG    1 
ATOM   2483 C  CD    . PRO A 1 316 ? 98.375  118.621 159.426 1.00 57.88  ? 316 PRO A CD    1 
ATOM   2484 N  N     . PRO A 1 317 ? 96.997  122.661 161.276 1.00 60.39  ? 317 PRO A N     1 
ATOM   2485 C  CA    . PRO A 1 317 ? 97.403  124.071 161.287 1.00 63.59  ? 317 PRO A CA    1 
ATOM   2486 C  C     . PRO A 1 317 ? 98.504  124.329 162.301 1.00 66.33  ? 317 PRO A C     1 
ATOM   2487 O  O     . PRO A 1 317 ? 99.537  124.922 161.976 1.00 66.82  ? 317 PRO A O     1 
ATOM   2488 C  CB    . PRO A 1 317 ? 96.110  124.811 161.658 1.00 67.26  ? 317 PRO A CB    1 
ATOM   2489 C  CG    . PRO A 1 317 ? 95.007  123.815 161.457 1.00 68.74  ? 317 PRO A CG    1 
ATOM   2490 C  CD    . PRO A 1 317 ? 95.612  122.483 161.734 1.00 64.03  ? 317 PRO A CD    1 
ATOM   2491 N  N     . THR A 1 318 ? 98.290  123.880 163.531 1.00 62.81  ? 318 THR A N     1 
ATOM   2492 C  CA    . THR A 1 318 ? 99.256  123.998 164.612 1.00 59.77  ? 318 THR A CA    1 
ATOM   2493 C  C     . THR A 1 318 ? 99.600  122.607 165.134 1.00 61.38  ? 318 THR A C     1 
ATOM   2494 O  O     . THR A 1 318 ? 99.044  121.598 164.697 1.00 71.44  ? 318 THR A O     1 
ATOM   2495 C  CB    . THR A 1 318 ? 98.715  124.875 165.744 1.00 63.56  ? 318 THR A CB    1 
ATOM   2496 O  OG1   . THR A 1 318 ? 97.973  124.064 166.662 1.00 66.96  ? 318 THR A OG1   1 
ATOM   2497 C  CG2   . THR A 1 318 ? 97.808  125.963 165.197 1.00 66.59  ? 318 THR A CG2   1 
ATOM   2498 N  N     . ALA A 1 319 ? 100.534 122.560 166.083 1.00 58.94  ? 319 ALA A N     1 
ATOM   2499 C  CA    . ALA A 1 319 ? 100.901 121.290 166.696 1.00 59.09  ? 319 ALA A CA    1 
ATOM   2500 C  C     . ALA A 1 319 ? 99.848  120.807 167.684 1.00 61.93  ? 319 ALA A C     1 
ATOM   2501 O  O     . ALA A 1 319 ? 99.697  119.597 167.880 1.00 61.12  ? 319 ALA A O     1 
ATOM   2502 C  CB    . ALA A 1 319 ? 102.255 121.415 167.390 1.00 64.08  ? 319 ALA A CB    1 
ATOM   2503 N  N     . ALA A 1 320 ? 99.122  121.730 168.315 1.00 64.10  ? 320 ALA A N     1 
ATOM   2504 C  CA    . ALA A 1 320 ? 98.062  121.358 169.242 1.00 66.87  ? 320 ALA A CA    1 
ATOM   2505 C  C     . ALA A 1 320 ? 96.803  120.882 168.533 1.00 72.81  ? 320 ALA A C     1 
ATOM   2506 O  O     . ALA A 1 320 ? 96.026  120.120 169.122 1.00 77.17  ? 320 ALA A O     1 
ATOM   2507 C  CB    . ALA A 1 320 ? 97.723  122.538 170.154 1.00 67.65  ? 320 ALA A CB    1 
ATOM   2508 N  N     . ASP A 1 321 ? 96.577  121.320 167.293 1.00 72.21  ? 321 ASP A N     1 
ATOM   2509 C  CA    . ASP A 1 321 ? 95.388  120.890 166.567 1.00 70.92  ? 321 ASP A CA    1 
ATOM   2510 C  C     . ASP A 1 321 ? 95.443  119.402 166.252 1.00 69.41  ? 321 ASP A C     1 
ATOM   2511 O  O     . ASP A 1 321 ? 94.411  118.723 166.257 1.00 76.18  ? 321 ASP A O     1 
ATOM   2512 C  CB    . ASP A 1 321 ? 95.230  121.705 165.286 1.00 68.64  ? 321 ASP A CB    1 
ATOM   2513 C  CG    . ASP A 1 321 ? 93.780  121.955 164.935 1.00 80.75  ? 321 ASP A CG    1 
ATOM   2514 O  OD1   . ASP A 1 321 ? 93.073  120.982 164.603 1.00 79.80  ? 321 ASP A OD1   1 
ATOM   2515 O  OD2   . ASP A 1 321 ? 93.346  123.124 164.995 1.00 91.78  ? 321 ASP A OD2   1 
ATOM   2516 N  N     . LEU A 1 322 ? 96.638  118.875 165.980 1.00 62.62  ? 322 LEU A N     1 
ATOM   2517 C  CA    . LEU A 1 322 ? 96.784  117.438 165.777 1.00 63.32  ? 322 LEU A CA    1 
ATOM   2518 C  C     . LEU A 1 322 ? 96.400  116.666 167.034 1.00 70.66  ? 322 LEU A C     1 
ATOM   2519 O  O     . LEU A 1 322 ? 95.687  115.656 166.961 1.00 77.10  ? 322 LEU A O     1 
ATOM   2520 C  CB    . LEU A 1 322 ? 98.218  117.117 165.361 1.00 58.20  ? 322 LEU A CB    1 
ATOM   2521 C  CG    . LEU A 1 322 ? 98.679  115.666 165.462 1.00 56.19  ? 322 LEU A CG    1 
ATOM   2522 C  CD1   . LEU A 1 322 ? 97.833  114.774 164.573 1.00 59.88  ? 322 LEU A CD1   1 
ATOM   2523 C  CD2   . LEU A 1 322 ? 100.144 115.561 165.090 1.00 54.62  ? 322 LEU A CD2   1 
ATOM   2524 N  N     . ALA A 1 323 ? 96.855  117.133 168.198 1.00 65.70  ? 323 ALA A N     1 
ATOM   2525 C  CA    . ALA A 1 323 ? 96.498  116.480 169.453 1.00 61.12  ? 323 ALA A CA    1 
ATOM   2526 C  C     . ALA A 1 323 ? 94.999  116.559 169.709 1.00 67.57  ? 323 ALA A C     1 
ATOM   2527 O  O     . ALA A 1 323 ? 94.383  115.581 170.150 1.00 71.07  ? 323 ALA A O     1 
ATOM   2528 C  CB    . ALA A 1 323 ? 97.271  117.113 170.608 1.00 65.93  ? 323 ALA A CB    1 
ATOM   2529 N  N     . ARG A 1 324 ? 94.397  117.720 169.441 1.00 68.67  ? 324 ARG A N     1 
ATOM   2530 C  CA    . ARG A 1 324 ? 92.959  117.869 169.643 1.00 73.81  ? 324 ARG A CA    1 
ATOM   2531 C  C     . ARG A 1 324 ? 92.173  116.942 168.724 1.00 74.91  ? 324 ARG A C     1 
ATOM   2532 O  O     . ARG A 1 324 ? 91.194  116.316 169.150 1.00 79.67  ? 324 ARG A O     1 
ATOM   2533 C  CB    . ARG A 1 324 ? 92.547  119.323 169.421 1.00 71.72  ? 324 ARG A CB    1 
ATOM   2534 C  CG    . ARG A 1 324 ? 92.703  120.198 170.651 1.00 78.93  ? 324 ARG A CG    1 
ATOM   2535 C  CD    . ARG A 1 324 ? 92.039  121.549 170.460 1.00 85.63  ? 324 ARG A CD    1 
ATOM   2536 N  NE    . ARG A 1 324 ? 92.990  122.561 170.016 1.00 94.86  ? 324 ARG A NE    1 
ATOM   2537 C  CZ    . ARG A 1 324 ? 93.558  123.455 170.813 1.00 98.49  ? 324 ARG A CZ    1 
ATOM   2538 N  NH1   . ARG A 1 324 ? 93.294  123.492 172.109 1.00 98.43  ? 324 ARG A NH1   1 
ATOM   2539 N  NH2   . ARG A 1 324 ? 94.413  124.334 170.298 1.00 93.42  ? 324 ARG A NH2   1 
ATOM   2540 N  N     . ARG A 1 325 ? 92.589  116.839 167.459 1.00 70.73  ? 325 ARG A N     1 
ATOM   2541 C  CA    . ARG A 1 325 ? 91.912  115.941 166.531 1.00 72.64  ? 325 ARG A CA    1 
ATOM   2542 C  C     . ARG A 1 325 ? 92.060  114.489 166.961 1.00 77.37  ? 325 ARG A C     1 
ATOM   2543 O  O     . ARG A 1 325 ? 91.106  113.710 166.867 1.00 88.89  ? 325 ARG A O     1 
ATOM   2544 C  CB    . ARG A 1 325 ? 92.455  116.130 165.117 1.00 70.31  ? 325 ARG A CB    1 
ATOM   2545 C  CG    . ARG A 1 325 ? 91.725  115.303 164.074 1.00 71.45  ? 325 ARG A CG    1 
ATOM   2546 C  CD    . ARG A 1 325 ? 92.545  115.158 162.808 1.00 73.01  ? 325 ARG A CD    1 
ATOM   2547 N  NE    . ARG A 1 325 ? 91.742  114.678 161.690 1.00 78.52  ? 325 ARG A NE    1 
ATOM   2548 C  CZ    . ARG A 1 325 ? 91.550  113.398 161.402 1.00 80.70  ? 325 ARG A CZ    1 
ATOM   2549 N  NH1   . ARG A 1 325 ? 92.082  112.437 162.140 1.00 80.81  ? 325 ARG A NH1   1 
ATOM   2550 N  NH2   . ARG A 1 325 ? 90.806  113.074 160.349 1.00 78.52  ? 325 ARG A NH2   1 
ATOM   2551 N  N     . PHE A 1 326 ? 93.251  114.101 167.424 1.00 68.83  ? 326 PHE A N     1 
ATOM   2552 C  CA    . PHE A 1 326 ? 93.438  112.729 167.884 1.00 68.26  ? 326 PHE A CA    1 
ATOM   2553 C  C     . PHE A 1 326 ? 92.560  112.430 169.092 1.00 76.37  ? 326 PHE A C     1 
ATOM   2554 O  O     . PHE A 1 326 ? 91.952  111.356 169.175 1.00 84.07  ? 326 PHE A O     1 
ATOM   2555 C  CB    . PHE A 1 326 ? 94.907  112.474 168.213 1.00 72.42  ? 326 PHE A CB    1 
ATOM   2556 C  CG    . PHE A 1 326 ? 95.241  111.021 168.390 1.00 73.31  ? 326 PHE A CG    1 
ATOM   2557 C  CD1   . PHE A 1 326 ? 94.895  110.097 167.422 1.00 76.23  ? 326 PHE A CD1   1 
ATOM   2558 C  CD2   . PHE A 1 326 ? 95.902  110.580 169.521 1.00 71.86  ? 326 PHE A CD2   1 
ATOM   2559 C  CE1   . PHE A 1 326 ? 95.201  108.761 167.580 1.00 79.18  ? 326 PHE A CE1   1 
ATOM   2560 C  CE2   . PHE A 1 326 ? 96.211  109.246 169.684 1.00 72.34  ? 326 PHE A CE2   1 
ATOM   2561 C  CZ    . PHE A 1 326 ? 95.860  108.335 168.713 1.00 75.68  ? 326 PHE A CZ    1 
ATOM   2562 N  N     . PHE A 1 327 ? 92.480  113.369 170.039 1.00 75.74  ? 327 PHE A N     1 
ATOM   2563 C  CA    . PHE A 1 327 ? 91.624  113.167 171.204 1.00 77.18  ? 327 PHE A CA    1 
ATOM   2564 C  C     . PHE A 1 327 ? 90.161  113.050 170.799 1.00 82.36  ? 327 PHE A C     1 
ATOM   2565 O  O     . PHE A 1 327 ? 89.436  112.186 171.307 1.00 88.78  ? 327 PHE A O     1 
ATOM   2566 C  CB    . PHE A 1 327 ? 91.812  114.308 172.202 1.00 74.48  ? 327 PHE A CB    1 
ATOM   2567 C  CG    . PHE A 1 327 ? 93.053  114.185 173.035 1.00 73.52  ? 327 PHE A CG    1 
ATOM   2568 C  CD1   . PHE A 1 327 ? 93.545  112.942 173.389 1.00 77.60  ? 327 PHE A CD1   1 
ATOM   2569 C  CD2   . PHE A 1 327 ? 93.726  115.314 173.466 1.00 72.27  ? 327 PHE A CD2   1 
ATOM   2570 C  CE1   . PHE A 1 327 ? 94.685  112.828 174.155 1.00 78.69  ? 327 PHE A CE1   1 
ATOM   2571 C  CE2   . PHE A 1 327 ? 94.866  115.204 174.232 1.00 75.48  ? 327 PHE A CE2   1 
ATOM   2572 C  CZ    . PHE A 1 327 ? 95.347  113.960 174.576 1.00 73.43  ? 327 PHE A CZ    1 
ATOM   2573 N  N     . ALA A 1 328 ? 89.709  113.911 169.883 1.00 81.90  ? 328 ALA A N     1 
ATOM   2574 C  CA    . ALA A 1 328 ? 88.323  113.844 169.430 1.00 86.95  ? 328 ALA A CA    1 
ATOM   2575 C  C     . ALA A 1 328 ? 88.035  112.525 168.727 1.00 89.83  ? 328 ALA A C     1 
ATOM   2576 O  O     . ALA A 1 328 ? 86.985  111.911 168.950 1.00 94.90  ? 328 ALA A O     1 
ATOM   2577 C  CB    . ALA A 1 328 ? 88.013  115.023 168.509 1.00 85.37  ? 328 ALA A CB    1 
ATOM   2578 N  N     . PHE A 1 329 ? 88.956  112.072 167.872 1.00 86.80  ? 329 PHE A N     1 
ATOM   2579 C  CA    . PHE A 1 329 ? 88.763  110.806 167.175 1.00 89.13  ? 329 PHE A CA    1 
ATOM   2580 C  C     . PHE A 1 329 ? 88.703  109.641 168.153 1.00 90.88  ? 329 PHE A C     1 
ATOM   2581 O  O     . PHE A 1 329 ? 87.841  108.762 168.031 1.00 101.54 ? 329 PHE A O     1 
ATOM   2582 C  CB    . PHE A 1 329 ? 89.884  110.594 166.158 1.00 87.90  ? 329 PHE A CB    1 
ATOM   2583 C  CG    . PHE A 1 329 ? 90.142  109.151 165.827 1.00 87.65  ? 329 PHE A CG    1 
ATOM   2584 C  CD1   . PHE A 1 329 ? 89.300  108.462 164.973 1.00 90.39  ? 329 PHE A CD1   1 
ATOM   2585 C  CD2   . PHE A 1 329 ? 91.231  108.487 166.366 1.00 84.58  ? 329 PHE A CD2   1 
ATOM   2586 C  CE1   . PHE A 1 329 ? 89.536  107.137 164.666 1.00 92.07  ? 329 PHE A CE1   1 
ATOM   2587 C  CE2   . PHE A 1 329 ? 91.470  107.162 166.063 1.00 86.25  ? 329 PHE A CE2   1 
ATOM   2588 C  CZ    . PHE A 1 329 ? 90.623  106.487 165.211 1.00 91.08  ? 329 PHE A CZ    1 
ATOM   2589 N  N     . LEU A 1 330 ? 89.612  109.618 169.132 1.00 84.07  ? 330 LEU A N     1 
ATOM   2590 C  CA    . LEU A 1 330 ? 89.603  108.543 170.118 1.00 87.47  ? 330 LEU A CA    1 
ATOM   2591 C  C     . LEU A 1 330 ? 88.309  108.547 170.919 1.00 96.16  ? 330 LEU A C     1 
ATOM   2592 O  O     . LEU A 1 330 ? 87.695  107.494 171.122 1.00 102.81 ? 330 LEU A O     1 
ATOM   2593 C  CB    . LEU A 1 330 ? 90.809  108.672 171.046 1.00 87.09  ? 330 LEU A CB    1 
ATOM   2594 C  CG    . LEU A 1 330 ? 92.096  107.983 170.592 1.00 83.84  ? 330 LEU A CG    1 
ATOM   2595 C  CD1   . LEU A 1 330 ? 93.153  108.063 171.677 1.00 86.04  ? 330 LEU A CD1   1 
ATOM   2596 C  CD2   . LEU A 1 330 ? 91.824  106.540 170.213 1.00 79.68  ? 330 LEU A CD2   1 
ATOM   2597 N  N     . ASN A 1 331 ? 87.868  109.727 171.362 1.00 95.40  ? 331 ASN A N     1 
ATOM   2598 C  CA    . ASN A 1 331 ? 86.633  109.815 172.134 1.00 97.93  ? 331 ASN A CA    1 
ATOM   2599 C  C     . ASN A 1 331 ? 85.453  109.332 171.300 1.00 101.04 ? 331 ASN A C     1 
ATOM   2600 O  O     . ASN A 1 331 ? 84.621  108.553 171.780 1.00 106.70 ? 331 ASN A O     1 
ATOM   2601 C  CB    . ASN A 1 331 ? 86.458  111.263 172.621 1.00 95.80  ? 331 ASN A CB    1 
ATOM   2602 C  CG    . ASN A 1 331 ? 85.009  111.657 172.951 1.00 103.97 ? 331 ASN A CG    1 
ATOM   2603 O  OD1   . ASN A 1 331 ? 84.090  110.841 173.000 1.00 108.85 ? 331 ASN A OD1   1 
ATOM   2604 N  ND2   . ASN A 1 331 ? 84.816  112.949 173.184 1.00 106.03 ? 331 ASN A ND2   1 
ATOM   2605 N  N     . GLU A 1 332 ? 85.383  109.755 170.037 1.00 98.27  ? 332 GLU A N     1 
ATOM   2606 C  CA    . GLU A 1 332 ? 84.242  109.401 169.201 1.00 102.28 ? 332 GLU A CA    1 
ATOM   2607 C  C     . GLU A 1 332 ? 84.215  107.910 168.884 1.00 104.50 ? 332 GLU A C     1 
ATOM   2608 O  O     . GLU A 1 332 ? 83.144  107.293 168.880 1.00 110.20 ? 332 GLU A O     1 
ATOM   2609 C  CB    . GLU A 1 332 ? 84.264  110.227 167.914 1.00 102.80 ? 332 GLU A CB    1 
ATOM   2610 C  CG    . GLU A 1 332 ? 83.472  109.627 166.763 1.00 107.68 ? 332 GLU A CG    1 
ATOM   2611 C  CD    . GLU A 1 332 ? 84.356  108.946 165.737 1.00 111.75 ? 332 GLU A CD    1 
ATOM   2612 O  OE1   . GLU A 1 332 ? 85.235  109.620 165.160 1.00 108.74 ? 332 GLU A OE1   1 
ATOM   2613 O  OE2   . GLU A 1 332 ? 84.171  107.732 165.508 1.00 112.49 ? 332 GLU A OE2   1 
ATOM   2614 N  N     . ARG A 1 333 ? 85.376  107.305 168.625 1.00 102.78 ? 333 ARG A N     1 
ATOM   2615 C  CA    . ARG A 1 333 ? 85.397  105.945 168.103 1.00 104.85 ? 333 ARG A CA    1 
ATOM   2616 C  C     . ARG A 1 333 ? 85.703  104.878 169.147 1.00 106.83 ? 333 ARG A C     1 
ATOM   2617 O  O     . ARG A 1 333 ? 85.650  103.689 168.815 1.00 111.07 ? 333 ARG A O     1 
ATOM   2618 C  CB    . ARG A 1 333 ? 86.410  105.835 166.960 1.00 101.40 ? 333 ARG A CB    1 
ATOM   2619 C  CG    . ARG A 1 333 ? 87.813  105.491 167.405 1.00 100.59 ? 333 ARG A CG    1 
ATOM   2620 C  CD    . ARG A 1 333 ? 88.307  104.268 166.663 1.00 104.19 ? 333 ARG A CD    1 
ATOM   2621 N  NE    . ARG A 1 333 ? 87.450  103.111 166.890 1.00 111.92 ? 333 ARG A NE    1 
ATOM   2622 C  CZ    . ARG A 1 333 ? 87.606  101.936 166.297 1.00 112.25 ? 333 ARG A CZ    1 
ATOM   2623 N  NH1   . ARG A 1 333 ? 88.577  101.727 165.422 1.00 103.08 ? 333 ARG A NH1   1 
ATOM   2624 N  NH2   . ARG A 1 333 ? 86.767  100.946 166.587 1.00 116.28 ? 333 ARG A NH2   1 
ATOM   2625 N  N     . MET A 1 334 ? 86.013  105.249 170.389 1.00 105.42 ? 334 MET A N     1 
ATOM   2626 C  CA    . MET A 1 334 ? 86.268  104.232 171.400 1.00 110.60 ? 334 MET A CA    1 
ATOM   2627 C  C     . MET A 1 334 ? 84.999  103.697 172.046 1.00 119.61 ? 334 MET A C     1 
ATOM   2628 O  O     . MET A 1 334 ? 85.060  102.667 172.725 1.00 121.41 ? 334 MET A O     1 
ATOM   2629 C  CB    . MET A 1 334 ? 87.204  104.782 172.477 1.00 108.83 ? 334 MET A CB    1 
ATOM   2630 C  CG    . MET A 1 334 ? 88.652  104.390 172.268 1.00 104.85 ? 334 MET A CG    1 
ATOM   2631 S  SD    . MET A 1 334 ? 88.792  102.672 171.744 1.00 110.80 ? 334 MET A SD    1 
ATOM   2632 C  CE    . MET A 1 334 ? 90.564  102.448 171.793 1.00 100.21 ? 334 MET A CE    1 
ATOM   2633 N  N     . GLU A 1 335 ? 83.856  104.361 171.857 1.00 121.61 ? 335 GLU A N     1 
ATOM   2634 C  CA    . GLU A 1 335 ? 82.606  103.829 172.384 1.00 122.25 ? 335 GLU A CA    1 
ATOM   2635 C  C     . GLU A 1 335 ? 82.193  102.541 171.686 1.00 123.39 ? 335 GLU A C     1 
ATOM   2636 O  O     . GLU A 1 335 ? 81.375  101.791 172.229 1.00 126.38 ? 335 GLU A O     1 
ATOM   2637 C  CB    . GLU A 1 335 ? 81.493  104.872 172.264 1.00 123.36 ? 335 GLU A CB    1 
ATOM   2638 C  CG    . GLU A 1 335 ? 81.317  105.444 170.869 1.00 125.84 ? 335 GLU A CG    1 
ATOM   2639 C  CD    . GLU A 1 335 ? 80.279  104.695 170.058 1.00 134.42 ? 335 GLU A CD    1 
ATOM   2640 O  OE1   . GLU A 1 335 ? 79.527  103.893 170.650 1.00 135.76 ? 335 GLU A OE1   1 
ATOM   2641 O  OE2   . GLU A 1 335 ? 80.213  104.910 168.830 1.00 133.80 ? 335 GLU A OE2   1 
ATOM   2642 N  N     . LYS A 1 336 ? 82.735  102.273 170.495 1.00 123.82 ? 336 LYS A N     1 
ATOM   2643 C  CA    . LYS A 1 336 ? 82.458  101.008 169.823 1.00 128.50 ? 336 LYS A CA    1 
ATOM   2644 C  C     . LYS A 1 336 ? 83.023  99.831  170.607 1.00 129.59 ? 336 LYS A C     1 
ATOM   2645 O  O     . LYS A 1 336 ? 82.389  98.773  170.693 1.00 133.82 ? 336 LYS A O     1 
ATOM   2646 C  CB    . LYS A 1 336 ? 83.033  101.019 168.406 1.00 30.00  ? 336 LYS A CB    1 
ATOM   2647 C  CG    . LYS A 1 336 ? 82.353  102.003 167.466 1.00 30.00  ? 336 LYS A CG    1 
ATOM   2648 C  CD    . LYS A 1 336 ? 82.987  101.979 166.086 1.00 30.00  ? 336 LYS A CD    1 
ATOM   2649 C  CE    . LYS A 1 336 ? 82.293  102.945 165.141 1.00 30.00  ? 336 LYS A CE    1 
ATOM   2650 N  NZ    . LYS A 1 336 ? 82.920  102.949 163.791 1.00 30.00  ? 336 LYS A NZ    1 
ATOM   2651 N  N     . VAL A 1 337 ? 84.210  99.993  171.182 1.00 126.37 ? 337 VAL A N     1 
ATOM   2652 C  CA    . VAL A 1 337 ? 84.833  98.932  171.964 1.00 129.94 ? 337 VAL A CA    1 
ATOM   2653 C  C     . VAL A 1 337 ? 84.188  98.889  173.342 1.00 135.94 ? 337 VAL A C     1 
ATOM   2654 O  O     . VAL A 1 337 ? 84.121  99.906  174.043 1.00 134.67 ? 337 VAL A O     1 
ATOM   2655 C  CB    . VAL A 1 337 ? 86.352  99.149  172.064 1.00 127.28 ? 337 VAL A CB    1 
ATOM   2656 C  CG1   . VAL A 1 337 ? 86.910  98.476  173.309 1.00 122.55 ? 337 VAL A CG1   1 
ATOM   2657 C  CG2   . VAL A 1 337 ? 87.044  98.625  170.817 1.00 124.57 ? 337 VAL A CG2   1 
ATOM   2658 N  N     . ASN A 1 338 ? 83.702  97.713  173.730 1.00 139.44 ? 338 ASN A N     1 
ATOM   2659 C  CA    . ASN A 1 338 ? 83.069  97.557  175.031 1.00 138.61 ? 338 ASN A CA    1 
ATOM   2660 C  C     . ASN A 1 338 ? 84.112  97.588  176.141 1.00 140.99 ? 338 ASN A C     1 
ATOM   2661 O  O     . ASN A 1 338 ? 85.243  97.127  175.967 1.00 140.18 ? 338 ASN A O     1 
ATOM   2662 C  CB    . ASN A 1 338 ? 82.282  96.248  175.085 1.00 139.45 ? 338 ASN A CB    1 
ATOM   2663 C  CG    . ASN A 1 338 ? 81.263  96.227  176.207 1.00 139.68 ? 338 ASN A CG    1 
ATOM   2664 O  OD1   . ASN A 1 338 ? 81.157  97.176  176.984 1.00 138.22 ? 338 ASN A OD1   1 
ATOM   2665 N  ND2   . ASN A 1 338 ? 80.505  95.140  176.298 1.00 138.20 ? 338 ASN A ND2   1 
ATOM   2666 N  N     . GLY A 1 339 ? 83.722  98.134  177.288 1.00 140.46 ? 339 GLY A N     1 
ATOM   2667 C  CA    . GLY A 1 339 ? 84.615  98.230  178.428 1.00 134.42 ? 339 GLY A CA    1 
ATOM   2668 C  C     . GLY A 1 339 ? 83.940  98.773  179.671 1.00 131.46 ? 339 GLY A C     1 
ATOM   2669 O  O     . GLY A 1 339 ? 82.713  98.779  179.770 1.00 132.91 ? 339 GLY A O     1 
ATOM   2670 P  P     . DG  B 2 9   ? 130.671 81.255  166.737 1.00 202.74 ? 2   DG  C P     1 
ATOM   2671 O  OP1   . DG  B 2 9   ? 131.552 81.253  165.546 1.00 195.44 ? 2   DG  C OP1   1 
ATOM   2672 O  OP2   . DG  B 2 9   ? 130.535 80.031  167.558 1.00 198.85 ? 2   DG  C OP2   1 
ATOM   2673 O  "O5'" . DG  B 2 9   ? 131.079 82.456  167.718 1.00 199.31 ? 2   DG  C "O5'" 1 
ATOM   2674 C  "C5'" . DG  B 2 9   ? 132.138 83.341  167.365 1.00 194.44 ? 2   DG  C "C5'" 1 
ATOM   2675 C  "C4'" . DG  B 2 9   ? 131.622 84.756  167.149 1.00 193.25 ? 2   DG  C "C4'" 1 
ATOM   2676 O  "O4'" . DG  B 2 9   ? 131.853 85.147  165.773 1.00 189.05 ? 2   DG  C "O4'" 1 
ATOM   2677 C  "C3'" . DG  B 2 9   ? 130.128 84.946  167.375 1.00 192.22 ? 2   DG  C "C3'" 1 
ATOM   2678 O  "O3'" . DG  B 2 9   ? 129.830 86.309  167.723 1.00 192.50 ? 2   DG  C "O3'" 1 
ATOM   2679 C  "C2'" . DG  B 2 9   ? 129.565 84.605  166.001 1.00 188.69 ? 2   DG  C "C2'" 1 
ATOM   2680 C  "C1'" . DG  B 2 9   ? 130.619 85.223  165.081 1.00 187.38 ? 2   DG  C "C1'" 1 
ATOM   2681 N  N9    . DG  B 2 9   ? 130.763 84.532  163.801 1.00 186.03 ? 2   DG  C N9    1 
ATOM   2682 C  C8    . DG  B 2 9   ? 129.870 83.659  163.229 1.00 185.18 ? 2   DG  C C8    1 
ATOM   2683 N  N7    . DG  B 2 9   ? 130.264 83.193  162.076 1.00 182.46 ? 2   DG  C N7    1 
ATOM   2684 C  C5    . DG  B 2 9   ? 131.498 83.797  161.866 1.00 182.45 ? 2   DG  C C5    1 
ATOM   2685 C  C6    . DG  B 2 9   ? 132.402 83.674  160.781 1.00 181.34 ? 2   DG  C C6    1 
ATOM   2686 O  O6    . DG  B 2 9   ? 132.286 82.985  159.757 1.00 180.69 ? 2   DG  C O6    1 
ATOM   2687 N  N1    . DG  B 2 9   ? 133.539 84.462  160.965 1.00 180.97 ? 2   DG  C N1    1 
ATOM   2688 C  C2    . DG  B 2 9   ? 133.770 85.260  162.063 1.00 179.43 ? 2   DG  C C2    1 
ATOM   2689 N  N2    . DG  B 2 9   ? 134.922 85.948  162.066 1.00 176.35 ? 2   DG  C N2    1 
ATOM   2690 N  N3    . DG  B 2 9   ? 132.930 85.384  163.083 1.00 181.01 ? 2   DG  C N3    1 
ATOM   2691 C  C4    . DG  B 2 9   ? 131.819 84.625  162.919 1.00 183.47 ? 2   DG  C C4    1 
ATOM   2692 P  P     . DG  B 2 10  ? 130.721 87.133  168.783 1.00 198.62 ? 3   DG  C P     1 
ATOM   2693 O  OP1   . DG  B 2 10  ? 131.227 86.216  169.831 1.00 196.48 ? 3   DG  C OP1   1 
ATOM   2694 O  OP2   . DG  B 2 10  ? 129.900 88.295  169.189 1.00 192.89 ? 3   DG  C OP2   1 
ATOM   2695 O  "O5'" . DG  B 2 10  ? 131.934 87.696  167.902 1.00 195.25 ? 3   DG  C "O5'" 1 
ATOM   2696 C  "C5'" . DG  B 2 10  ? 132.815 88.680  168.428 1.00 191.71 ? 3   DG  C "C5'" 1 
ATOM   2697 C  "C4'" . DG  B 2 10  ? 132.875 89.892  167.512 1.00 188.54 ? 3   DG  C "C4'" 1 
ATOM   2698 O  "O4'" . DG  B 2 10  ? 132.691 89.472  166.129 1.00 185.13 ? 3   DG  C "O4'" 1 
ATOM   2699 C  "C3'" . DG  B 2 10  ? 131.798 90.942  167.767 1.00 186.84 ? 3   DG  C "C3'" 1 
ATOM   2700 O  "O3'" . DG  B 2 10  ? 132.299 92.232  167.459 1.00 189.02 ? 3   DG  C "O3'" 1 
ATOM   2701 C  "C2'" . DG  B 2 10  ? 130.717 90.533  166.778 1.00 182.47 ? 3   DG  C "C2'" 1 
ATOM   2702 C  "C1'" . DG  B 2 10  ? 131.571 90.141  165.582 1.00 182.22 ? 3   DG  C "C1'" 1 
ATOM   2703 N  N9    . DG  B 2 10  ? 130.897 89.244  164.645 1.00 181.56 ? 3   DG  C N9    1 
ATOM   2704 C  C8    . DG  B 2 10  ? 129.677 88.637  164.818 1.00 180.91 ? 3   DG  C C8    1 
ATOM   2705 N  N7    . DG  B 2 10  ? 129.320 87.888  163.813 1.00 178.23 ? 3   DG  C N7    1 
ATOM   2706 C  C5    . DG  B 2 10  ? 130.371 88.001  162.913 1.00 177.54 ? 3   DG  C C5    1 
ATOM   2707 C  C6    . DG  B 2 10  ? 130.547 87.408  161.640 1.00 175.02 ? 3   DG  C C6    1 
ATOM   2708 O  O6    . DG  B 2 10  ? 129.782 86.642  161.038 1.00 171.77 ? 3   DG  C O6    1 
ATOM   2709 N  N1    . DG  B 2 10  ? 131.753 87.790  161.053 1.00 175.51 ? 3   DG  C N1    1 
ATOM   2710 C  C2    . DG  B 2 10  ? 132.675 88.632  161.633 1.00 175.76 ? 3   DG  C C2    1 
ATOM   2711 N  N2    . DG  B 2 10  ? 133.782 88.884  160.915 1.00 176.85 ? 3   DG  C N2    1 
ATOM   2712 N  N3    . DG  B 2 10  ? 132.521 89.195  162.826 1.00 176.07 ? 3   DG  C N3    1 
ATOM   2713 C  C4    . DG  B 2 10  ? 131.350 88.835  163.408 1.00 178.66 ? 3   DG  C C4    1 
ATOM   2714 P  P     . DT  B 2 11  ? 133.574 92.831  168.232 1.00 196.59 ? 4   DT  C P     1 
ATOM   2715 O  OP1   . DT  B 2 11  ? 134.785 92.479  167.457 1.00 191.76 ? 4   DT  C OP1   1 
ATOM   2716 O  OP2   . DT  B 2 11  ? 133.474 92.443  169.656 1.00 189.34 ? 4   DT  C OP2   1 
ATOM   2717 O  "O5'" . DT  B 2 11  ? 133.347 94.409  168.140 1.00 190.95 ? 4   DT  C "O5'" 1 
ATOM   2718 C  "C5'" . DT  B 2 11  ? 132.563 94.949  167.080 1.00 185.70 ? 4   DT  C "C5'" 1 
ATOM   2719 C  "C4'" . DT  B 2 11  ? 133.347 94.961  165.779 1.00 179.76 ? 4   DT  C "C4'" 1 
ATOM   2720 O  "O4'" . DT  B 2 11  ? 132.980 93.807  164.971 1.00 177.01 ? 4   DT  C "O4'" 1 
ATOM   2721 C  "C3'" . DT  B 2 11  ? 133.103 96.177  164.894 1.00 176.19 ? 4   DT  C "C3'" 1 
ATOM   2722 O  "O3'" . DT  B 2 11  ? 134.306 96.522  164.223 1.00 177.30 ? 4   DT  C "O3'" 1 
ATOM   2723 C  "C2'" . DT  B 2 11  ? 132.042 95.669  163.922 1.00 170.97 ? 4   DT  C "C2'" 1 
ATOM   2724 C  "C1'" . DT  B 2 11  ? 132.515 94.242  163.708 1.00 171.46 ? 4   DT  C "C1'" 1 
ATOM   2725 N  N1    . DT  B 2 11  ? 131.444 93.303  163.248 1.00 170.88 ? 4   DT  C N1    1 
ATOM   2726 C  C2    . DT  B 2 11  ? 131.558 92.696  162.014 1.00 168.97 ? 4   DT  C C2    1 
ATOM   2727 O  O2    . DT  B 2 11  ? 132.492 92.891  161.258 1.00 167.94 ? 4   DT  C O2    1 
ATOM   2728 N  N3    . DT  B 2 11  ? 130.529 91.848  161.693 1.00 169.47 ? 4   DT  C N3    1 
ATOM   2729 C  C4    . DT  B 2 11  ? 129.424 91.550  162.471 1.00 168.17 ? 4   DT  C C4    1 
ATOM   2730 O  O4    . DT  B 2 11  ? 128.551 90.775  162.100 1.00 165.92 ? 4   DT  C O4    1 
ATOM   2731 C  C5    . DT  B 2 11  ? 129.368 92.217  163.751 1.00 169.82 ? 4   DT  C C5    1 
ATOM   2732 C  C7    . DT  B 2 11  ? 128.213 91.972  164.677 1.00 168.12 ? 4   DT  C C7    1 
ATOM   2733 C  C6    . DT  B 2 11  ? 130.368 93.051  164.073 1.00 171.94 ? 4   DT  C C6    1 
ATOM   2734 P  P     . DC  B 2 12  ? 134.491 97.983  163.582 1.00 179.31 ? 5   DC  C P     1 
ATOM   2735 O  OP1   . DC  B 2 12  ? 135.654 98.621  164.239 1.00 177.58 ? 5   DC  C OP1   1 
ATOM   2736 O  OP2   . DC  B 2 12  ? 133.175 98.659  163.602 1.00 169.27 ? 5   DC  C OP2   1 
ATOM   2737 O  "O5'" . DC  B 2 12  ? 134.872 97.678  162.061 1.00 172.13 ? 5   DC  C "O5'" 1 
ATOM   2738 C  "C5'" . DC  B 2 12  ? 134.578 96.405  161.501 1.00 167.96 ? 5   DC  C "C5'" 1 
ATOM   2739 C  "C4'" . DC  B 2 12  ? 134.411 96.507  160.000 1.00 158.26 ? 5   DC  C "C4'" 1 
ATOM   2740 O  "O4'" . DC  B 2 12  ? 133.402 95.558  159.561 1.00 154.92 ? 5   DC  C "O4'" 1 
ATOM   2741 C  "C3'" . DC  B 2 12  ? 133.932 97.863  159.508 1.00 154.35 ? 5   DC  C "C3'" 1 
ATOM   2742 O  "O3'" . DC  B 2 12  ? 134.415 98.089  158.191 1.00 155.64 ? 5   DC  C "O3'" 1 
ATOM   2743 C  "C2'" . DC  B 2 12  ? 132.421 97.690  159.532 1.00 150.26 ? 5   DC  C "C2'" 1 
ATOM   2744 C  "C1'" . DC  B 2 12  ? 132.275 96.252  159.059 1.00 149.89 ? 5   DC  C "C1'" 1 
ATOM   2745 N  N1    . DC  B 2 12  ? 131.043 95.581  159.565 1.00 150.02 ? 5   DC  C N1    1 
ATOM   2746 C  C2    . DC  B 2 12  ? 130.383 94.644  158.762 1.00 151.23 ? 5   DC  C C2    1 
ATOM   2747 O  O2    . DC  B 2 12  ? 130.835 94.387  157.642 1.00 152.13 ? 5   DC  C O2    1 
ATOM   2748 N  N3    . DC  B 2 12  ? 129.263 94.042  159.240 1.00 151.92 ? 5   DC  C N3    1 
ATOM   2749 C  C4    . DC  B 2 12  ? 128.810 94.351  160.456 1.00 153.47 ? 5   DC  C C4    1 
ATOM   2750 N  N4    . DC  B 2 12  ? 127.705 93.736  160.888 1.00 152.80 ? 5   DC  C N4    1 
ATOM   2751 C  C5    . DC  B 2 12  ? 129.468 95.305  161.285 1.00 153.83 ? 5   DC  C C5    1 
ATOM   2752 C  C6    . DC  B 2 12  ? 130.568 95.890  160.804 1.00 152.89 ? 5   DC  C C6    1 
ATOM   2753 P  P     . DT  B 2 13  ? 134.244 99.523  157.486 1.00 159.15 ? 6   DT  C P     1 
ATOM   2754 O  OP1   . DT  B 2 13  ? 135.599 99.994  157.125 1.00 155.53 ? 6   DT  C OP1   1 
ATOM   2755 O  OP2   . DT  B 2 13  ? 133.377 100.377 158.326 1.00 154.90 ? 6   DT  C OP2   1 
ATOM   2756 O  "O5'" . DT  B 2 13  ? 133.455 99.176  156.142 1.00 147.71 ? 6   DT  C "O5'" 1 
ATOM   2757 C  "C5'" . DT  B 2 13  ? 133.923 98.121  155.312 1.00 141.68 ? 6   DT  C "C5'" 1 
ATOM   2758 C  "C4'" . DT  B 2 13  ? 132.829 97.626  154.382 1.00 133.65 ? 6   DT  C "C4'" 1 
ATOM   2759 O  "O4'" . DT  B 2 13  ? 131.771 96.996  155.153 1.00 131.44 ? 6   DT  C "O4'" 1 
ATOM   2760 C  "C3'" . DT  B 2 13  ? 132.154 98.705  153.535 1.00 134.94 ? 6   DT  C "C3'" 1 
ATOM   2761 O  "O3'" . DT  B 2 13  ? 131.950 98.208  152.219 1.00 136.83 ? 6   DT  C "O3'" 1 
ATOM   2762 C  "C2'" . DT  B 2 13  ? 130.833 98.928  154.267 1.00 130.91 ? 6   DT  C "C2'" 1 
ATOM   2763 C  "C1'" . DT  B 2 13  ? 130.527 97.527  154.758 1.00 128.29 ? 6   DT  C "C1'" 1 
ATOM   2764 N  N1    . DT  B 2 13  ? 129.599 97.484  155.928 1.00 131.62 ? 6   DT  C N1    1 
ATOM   2765 C  C2    . DT  B 2 13  ? 128.544 96.599  155.917 1.00 132.04 ? 6   DT  C C2    1 
ATOM   2766 O  O2    . DT  B 2 13  ? 128.319 95.842  154.991 1.00 129.04 ? 6   DT  C O2    1 
ATOM   2767 N  N3    . DT  B 2 13  ? 127.757 96.633  157.037 1.00 137.06 ? 6   DT  C N3    1 
ATOM   2768 C  C4    . DT  B 2 13  ? 127.916 97.445  158.145 1.00 137.24 ? 6   DT  C C4    1 
ATOM   2769 O  O4    . DT  B 2 13  ? 127.156 97.402  159.104 1.00 137.72 ? 6   DT  C O4    1 
ATOM   2770 C  C5    . DT  B 2 13  ? 129.039 98.348  158.093 1.00 137.99 ? 6   DT  C C5    1 
ATOM   2771 C  C7    . DT  B 2 13  ? 129.306 99.278  159.239 1.00 140.45 ? 6   DT  C C7    1 
ATOM   2772 C  C6    . DT  B 2 13  ? 129.818 98.324  157.000 1.00 136.82 ? 6   DT  C C6    1 
ATOM   2773 P  P     . DT  B 2 14  ? 131.414 99.159  151.039 1.00 128.55 ? 7   DT  C P     1 
ATOM   2774 O  OP1   . DT  B 2 14  ? 132.493 99.240  150.031 1.00 123.18 ? 7   DT  C OP1   1 
ATOM   2775 O  OP2   . DT  B 2 14  ? 130.862 100.407 151.609 1.00 118.67 ? 7   DT  C OP2   1 
ATOM   2776 O  "O5'" . DT  B 2 14  ? 130.201 98.320  150.428 1.00 120.49 ? 7   DT  C "O5'" 1 
ATOM   2777 C  "C5'" . DT  B 2 14  ? 129.801 97.112  151.065 1.00 120.52 ? 7   DT  C "C5'" 1 
ATOM   2778 C  "C4'" . DT  B 2 14  ? 128.515 96.572  150.470 1.00 110.49 ? 7   DT  C "C4'" 1 
ATOM   2779 O  "O4'" . DT  B 2 14  ? 127.541 96.372  151.527 1.00 107.53 ? 7   DT  C "O4'" 1 
ATOM   2780 C  "C3'" . DT  B 2 14  ? 127.829 97.486  149.472 1.00 107.83 ? 7   DT  C "C3'" 1 
ATOM   2781 O  "O3'" . DT  B 2 14  ? 127.023 96.705  148.602 1.00 113.19 ? 7   DT  C "O3'" 1 
ATOM   2782 C  "C2'" . DT  B 2 14  ? 126.981 98.357  150.389 1.00 105.50 ? 7   DT  C "C2'" 1 
ATOM   2783 C  "C1'" . DT  B 2 14  ? 126.507 97.334  151.416 1.00 104.74 ? 7   DT  C "C1'" 1 
ATOM   2784 N  N1    . DT  B 2 14  ? 126.258 97.909  152.771 1.00 108.67 ? 7   DT  C N1    1 
ATOM   2785 C  C2    . DT  B 2 14  ? 125.212 97.428  153.524 1.00 108.19 ? 7   DT  C C2    1 
ATOM   2786 O  O2    . DT  B 2 14  ? 124.462 96.549  153.141 1.00 106.75 ? 7   DT  C O2    1 
ATOM   2787 N  N3    . DT  B 2 14  ? 125.074 98.018  154.752 1.00 111.71 ? 7   DT  C N3    1 
ATOM   2788 C  C4    . DT  B 2 14  ? 125.859 99.017  155.292 1.00 114.93 ? 7   DT  C C4    1 
ATOM   2789 O  O4    . DT  B 2 14  ? 125.655 99.484  156.406 1.00 117.64 ? 7   DT  C O4    1 
ATOM   2790 C  C5    . DT  B 2 14  ? 126.936 99.475  154.453 1.00 114.57 ? 7   DT  C C5    1 
ATOM   2791 C  C7    . DT  B 2 14  ? 127.851 100.561 154.936 1.00 117.94 ? 7   DT  C C7    1 
ATOM   2792 C  C6    . DT  B 2 14  ? 127.084 98.906  153.246 1.00 112.99 ? 7   DT  C C6    1 
ATOM   2793 P  P     . DC  B 2 15  ? 126.391 97.339  147.269 1.00 116.80 ? 8   DC  C P     1 
ATOM   2794 O  OP1   . DC  B 2 15  ? 126.846 96.516  146.128 1.00 108.35 ? 8   DC  C OP1   1 
ATOM   2795 O  OP2   . DC  B 2 15  ? 126.650 98.796  147.270 1.00 108.69 ? 8   DC  C OP2   1 
ATOM   2796 O  "O5'" . DC  B 2 15  ? 124.822 97.111  147.459 1.00 115.06 ? 8   DC  C "O5'" 1 
ATOM   2797 C  "C5'" . DC  B 2 15  ? 124.333 95.816  147.795 1.00 107.41 ? 8   DC  C "C5'" 1 
ATOM   2798 C  "C4'" . DC  B 2 15  ? 122.906 95.890  148.311 1.00 103.98 ? 8   DC  C "C4'" 1 
ATOM   2799 O  "O4'" . DC  B 2 15  ? 122.897 96.446  149.653 1.00 101.74 ? 8   DC  C "O4'" 1 
ATOM   2800 C  "C3'" . DC  B 2 15  ? 121.967 96.765  147.486 1.00 95.75  ? 8   DC  C "C3'" 1 
ATOM   2801 O  "O3'" . DC  B 2 15  ? 120.685 96.164  147.421 1.00 91.72  ? 8   DC  C "O3'" 1 
ATOM   2802 C  "C2'" . DC  B 2 15  ? 121.934 98.065  148.282 1.00 91.11  ? 8   DC  C "C2'" 1 
ATOM   2803 C  "C1'" . DC  B 2 15  ? 122.009 97.539  149.703 1.00 93.34  ? 8   DC  C "C1'" 1 
ATOM   2804 N  N1    . DC  B 2 15  ? 122.537 98.529  150.676 1.00 94.78  ? 8   DC  C N1    1 
ATOM   2805 C  C2    . DC  B 2 15  ? 121.912 98.685  151.916 1.00 93.96  ? 8   DC  C C2    1 
ATOM   2806 O  O2    . DC  B 2 15  ? 120.924 97.991  152.181 1.00 92.79  ? 8   DC  C O2    1 
ATOM   2807 N  N3    . DC  B 2 15  ? 122.411 99.592  152.792 1.00 95.64  ? 8   DC  C N3    1 
ATOM   2808 C  C4    . DC  B 2 15  ? 123.480 100.317 152.463 1.00 96.31  ? 8   DC  C C4    1 
ATOM   2809 N  N4    . DC  B 2 15  ? 123.938 101.199 153.355 1.00 95.31  ? 8   DC  C N4    1 
ATOM   2810 C  C5    . DC  B 2 15  ? 124.126 100.172 151.204 1.00 97.96  ? 8   DC  C C5    1 
ATOM   2811 C  C6    . DC  B 2 15  ? 123.626 99.276  150.351 1.00 98.91  ? 8   DC  C C6    1 
ATOM   2812 P  P     . DA  B 2 16  ? 119.701 96.488  146.195 1.00 103.67 ? 9   DA  C P     1 
ATOM   2813 O  OP1   . DA  B 2 16  ? 119.655 95.293  145.325 1.00 103.57 ? 9   DA  C OP1   1 
ATOM   2814 O  OP2   . DA  B 2 16  ? 120.107 97.793  145.628 1.00 91.31  ? 9   DA  C OP2   1 
ATOM   2815 O  "O5'" . DA  B 2 16  ? 118.276 96.670  146.895 1.00 94.71  ? 9   DA  C "O5'" 1 
ATOM   2816 C  "C5'" . DA  B 2 16  ? 117.757 95.635  147.722 1.00 85.94  ? 9   DA  C "C5'" 1 
ATOM   2817 C  "C4'" . DA  B 2 16  ? 116.834 96.196  148.791 1.00 82.63  ? 9   DA  C "C4'" 1 
ATOM   2818 O  "O4'" . DA  B 2 16  ? 117.578 97.087  149.660 1.00 81.32  ? 9   DA  C "O4'" 1 
ATOM   2819 C  "C3'" . DA  B 2 16  ? 115.649 97.003  148.275 1.00 78.40  ? 9   DA  C "C3'" 1 
ATOM   2820 O  "O3'" . DA  B 2 16  ? 114.520 96.768  149.098 1.00 82.26  ? 9   DA  C "O3'" 1 
ATOM   2821 C  "C2'" . DA  B 2 16  ? 116.139 98.442  148.394 1.00 71.72  ? 9   DA  C "C2'" 1 
ATOM   2822 C  "C1'" . DA  B 2 16  ? 116.996 98.373  149.648 1.00 74.17  ? 9   DA  C "C1'" 1 
ATOM   2823 N  N9    . DA  B 2 16  ? 118.073 99.355  149.674 1.00 73.15  ? 9   DA  C N9    1 
ATOM   2824 C  C8    . DA  B 2 16  ? 118.995 99.590  148.698 1.00 78.62  ? 9   DA  C C8    1 
ATOM   2825 N  N7    . DA  B 2 16  ? 119.858 100.530 148.998 1.00 79.12  ? 9   DA  C N7    1 
ATOM   2826 C  C5    . DA  B 2 16  ? 119.477 100.936 150.261 1.00 73.78  ? 9   DA  C C5    1 
ATOM   2827 C  C6    . DA  B 2 16  ? 119.990 101.909 151.139 1.00 76.49  ? 9   DA  C C6    1 
ATOM   2828 N  N6    . DA  B 2 16  ? 121.047 102.673 150.851 1.00 75.72  ? 9   DA  C N6    1 
ATOM   2829 N  N1    . DA  B 2 16  ? 119.374 102.065 152.327 1.00 80.48  ? 9   DA  C N1    1 
ATOM   2830 C  C2    . DA  B 2 16  ? 118.317 101.297 152.611 1.00 78.01  ? 9   DA  C C2    1 
ATOM   2831 N  N3    . DA  B 2 16  ? 117.745 100.353 151.867 1.00 73.58  ? 9   DA  C N3    1 
ATOM   2832 C  C4    . DA  B 2 16  ? 118.380 100.220 150.695 1.00 71.94  ? 9   DA  C C4    1 
ATOM   2833 P  P     . DC  B 2 17  ? 113.049 97.184  148.608 1.00 87.89  ? 10  DC  C P     1 
ATOM   2834 O  OP1   . DC  B 2 17  ? 112.202 95.973  148.648 1.00 81.76  ? 10  DC  C OP1   1 
ATOM   2835 O  OP2   . DC  B 2 17  ? 113.177 97.946  147.349 1.00 76.05  ? 10  DC  C OP2   1 
ATOM   2836 O  "O5'" . DC  B 2 17  ? 112.552 98.195  149.738 1.00 78.87  ? 10  DC  C "O5'" 1 
ATOM   2837 C  "C5'" . DC  B 2 17  ? 112.725 97.865  151.111 1.00 75.37  ? 10  DC  C "C5'" 1 
ATOM   2838 C  "C4'" . DC  B 2 17  ? 112.240 98.993  152.000 1.00 65.95  ? 10  DC  C "C4'" 1 
ATOM   2839 O  "O4'" . DC  B 2 17  ? 113.334 99.905  152.274 1.00 62.61  ? 10  DC  C "O4'" 1 
ATOM   2840 C  "C3'" . DC  B 2 17  ? 111.124 99.837  151.405 1.00 66.01  ? 10  DC  C "C3'" 1 
ATOM   2841 O  "O3'" . DC  B 2 17  ? 110.210 100.216 152.413 1.00 73.18  ? 10  DC  C "O3'" 1 
ATOM   2842 C  "C2'" . DC  B 2 17  ? 111.864 101.041 150.837 1.00 63.55  ? 10  DC  C "C2'" 1 
ATOM   2843 C  "C1'" . DC  B 2 17  ? 113.019 101.202 151.812 1.00 60.05  ? 10  DC  C "C1'" 1 
ATOM   2844 N  N1    . DC  B 2 17  ? 114.239 101.771 151.188 1.00 56.20  ? 10  DC  C N1    1 
ATOM   2845 C  C2    . DC  B 2 17  ? 114.952 102.775 151.846 1.00 56.28  ? 10  DC  C C2    1 
ATOM   2846 O  O2    . DC  B 2 17  ? 114.545 103.180 152.940 1.00 59.94  ? 10  DC  C O2    1 
ATOM   2847 N  N3    . DC  B 2 17  ? 116.067 103.276 151.263 1.00 55.56  ? 10  DC  C N3    1 
ATOM   2848 C  C4    . DC  B 2 17  ? 116.466 102.808 150.082 1.00 60.46  ? 10  DC  C C4    1 
ATOM   2849 N  N4    . DC  B 2 17  ? 117.570 103.326 149.540 1.00 63.52  ? 10  DC  C N4    1 
ATOM   2850 C  C5    . DC  B 2 17  ? 115.752 101.784 149.401 1.00 63.78  ? 10  DC  C C5    1 
ATOM   2851 C  C6    . DC  B 2 17  ? 114.657 101.299 149.986 1.00 61.08  ? 10  DC  C C6    1 
ATOM   2852 P  P     . DA  B 2 18  ? 108.662 100.415 152.048 1.00 100.10 ? 11  DA  C P     1 
ATOM   2853 O  OP1   . DA  B 2 18  ? 107.863 99.650  153.029 1.00 91.65  ? 11  DA  C OP1   1 
ATOM   2854 O  OP2   . DA  B 2 18  ? 108.515 100.145 150.603 1.00 85.20  ? 11  DA  C OP2   1 
ATOM   2855 O  "O5'" . DA  B 2 18  ? 108.414 101.975 152.274 1.00 75.09  ? 11  DA  C "O5'" 1 
ATOM   2856 C  "C5'" . DA  B 2 18  ? 108.617 102.539 153.555 1.00 67.33  ? 11  DA  C "C5'" 1 
ATOM   2857 C  "C4'" . DA  B 2 18  ? 109.103 103.969 153.445 1.00 61.46  ? 11  DA  C "C4'" 1 
ATOM   2858 O  "O4'" . DA  B 2 18  ? 110.344 104.005 152.711 1.00 51.96  ? 11  DA  C "O4'" 1 
ATOM   2859 C  "C3'" . DA  B 2 18  ? 108.151 104.929 152.723 1.00 64.49  ? 11  DA  C "C3'" 1 
ATOM   2860 O  "O3'" . DA  B 2 18  ? 107.763 105.969 153.612 1.00 61.15  ? 11  DA  C "O3'" 1 
ATOM   2861 C  "C2'" . DA  B 2 18  ? 108.973 105.457 151.536 1.00 55.19  ? 11  DA  C "C2'" 1 
ATOM   2862 C  "C1'" . DA  B 2 18  ? 110.398 105.201 151.987 1.00 53.38  ? 11  DA  C "C1'" 1 
ATOM   2863 N  N9    . DA  B 2 18  ? 111.337 105.031 150.889 1.00 52.79  ? 11  DA  C N9    1 
ATOM   2864 C  C8    . DA  B 2 18  ? 111.257 104.127 149.874 1.00 53.11  ? 11  DA  C C8    1 
ATOM   2865 N  N7    . DA  B 2 18  ? 112.254 104.193 149.027 1.00 54.46  ? 11  DA  C N7    1 
ATOM   2866 C  C5    . DA  B 2 18  ? 113.040 105.217 149.519 1.00 50.04  ? 11  DA  C C5    1 
ATOM   2867 C  C6    . DA  B 2 18  ? 114.246 105.784 149.072 1.00 47.80  ? 11  DA  C C6    1 
ATOM   2868 N  N6    . DA  B 2 18  ? 114.889 105.372 147.977 1.00 50.72  ? 11  DA  C N6    1 
ATOM   2869 N  N1    . DA  B 2 18  ? 114.767 106.793 149.795 1.00 44.11  ? 11  DA  C N1    1 
ATOM   2870 C  C2    . DA  B 2 18  ? 114.121 107.201 150.891 1.00 42.30  ? 11  DA  C C2    1 
ATOM   2871 N  N3    . DA  B 2 18  ? 112.984 106.745 151.409 1.00 45.82  ? 11  DA  C N3    1 
ATOM   2872 C  C4    . DA  B 2 18  ? 112.491 105.743 150.669 1.00 50.70  ? 11  DA  C C4    1 
ATOM   2873 P  P     . DC  B 2 19  ? 107.037 107.293 153.067 1.00 59.25  ? 12  DC  C P     1 
ATOM   2874 O  OP1   . DC  B 2 19  ? 106.284 107.876 154.196 1.00 54.69  ? 12  DC  C OP1   1 
ATOM   2875 O  OP2   . DC  B 2 19  ? 106.325 106.968 151.813 1.00 56.92  ? 12  DC  C OP2   1 
ATOM   2876 O  "O5'" . DC  B 2 19  ? 108.249 108.283 152.753 1.00 55.48  ? 12  DC  C "O5'" 1 
ATOM   2877 C  "C5'" . DC  B 2 19  ? 109.079 108.751 153.809 1.00 48.62  ? 12  DC  C "C5'" 1 
ATOM   2878 C  "C4'" . DC  B 2 19  ? 109.760 110.037 153.400 1.00 38.22  ? 12  DC  C "C4'" 1 
ATOM   2879 O  "O4'" . DC  B 2 19  ? 110.980 109.723 152.710 1.00 29.76  ? 12  DC  C "O4'" 1 
ATOM   2880 C  "C3'" . DC  B 2 19  ? 108.947 110.873 152.435 1.00 45.99  ? 12  DC  C "C3'" 1 
ATOM   2881 O  "O3'" . DC  B 2 19  ? 108.193 111.830 153.158 1.00 48.75  ? 12  DC  C "O3'" 1 
ATOM   2882 C  "C2'" . DC  B 2 19  ? 109.991 111.543 151.543 1.00 42.78  ? 12  DC  C "C2'" 1 
ATOM   2883 C  "C1'" . DC  B 2 19  ? 111.237 110.680 151.707 1.00 34.15  ? 12  DC  C "C1'" 1 
ATOM   2884 N  N1    . DC  B 2 19  ? 111.638 109.953 150.483 1.00 36.83  ? 12  DC  C N1    1 
ATOM   2885 C  C2    . DC  B 2 19  ? 112.794 110.335 149.808 1.00 42.53  ? 12  DC  C C2    1 
ATOM   2886 O  O2    . DC  B 2 19  ? 113.441 111.294 150.236 1.00 42.30  ? 12  DC  C O2    1 
ATOM   2887 N  N3    . DC  B 2 19  ? 113.169 109.648 148.704 1.00 45.83  ? 12  DC  C N3    1 
ATOM   2888 C  C4    . DC  B 2 19  ? 112.436 108.619 148.282 1.00 44.08  ? 12  DC  C C4    1 
ATOM   2889 N  N4    . DC  B 2 19  ? 112.839 107.966 147.188 1.00 42.25  ? 12  DC  C N4    1 
ATOM   2890 C  C5    . DC  B 2 19  ? 111.254 108.213 148.962 1.00 45.20  ? 12  DC  C C5    1 
ATOM   2891 C  C6    . DC  B 2 19  ? 110.899 108.898 150.051 1.00 43.05  ? 12  DC  C C6    1 
ATOM   2892 P  P     . DC  B 2 20  ? 107.022 112.651 152.432 1.00 56.37  ? 13  DC  C P     1 
ATOM   2893 O  OP1   . DC  B 2 20  ? 106.165 113.216 153.493 1.00 54.34  ? 13  DC  C OP1   1 
ATOM   2894 O  OP2   . DC  B 2 20  ? 106.438 111.791 151.379 1.00 51.25  ? 13  DC  C OP2   1 
ATOM   2895 O  "O5'" . DC  B 2 20  ? 107.793 113.845 151.714 1.00 40.35  ? 13  DC  C "O5'" 1 
ATOM   2896 C  "C5'" . DC  B 2 20  ? 108.665 114.662 152.464 1.00 43.81  ? 13  DC  C "C5'" 1 
ATOM   2897 C  "C4'" . DC  B 2 20  ? 109.585 115.441 151.552 1.00 44.06  ? 13  DC  C "C4'" 1 
ATOM   2898 O  "O4'" . DC  B 2 20  ? 110.261 114.526 150.652 1.00 39.88  ? 13  DC  C "O4'" 1 
ATOM   2899 C  "C3'" . DC  B 2 20  ? 108.889 116.468 150.668 1.00 46.98  ? 13  DC  C "C3'" 1 
ATOM   2900 O  "O3'" . DC  B 2 20  ? 109.684 117.631 150.572 1.00 51.53  ? 13  DC  C "O3'" 1 
ATOM   2901 C  "C2'" . DC  B 2 20  ? 108.789 115.751 149.329 1.00 41.72  ? 13  DC  C "C2'" 1 
ATOM   2902 C  "C1'" . DC  B 2 20  ? 110.079 114.951 149.326 1.00 41.69  ? 13  DC  C "C1'" 1 
ATOM   2903 N  N1    . DC  B 2 20  ? 110.025 113.761 148.442 1.00 41.81  ? 13  DC  C N1    1 
ATOM   2904 C  C2    . DC  B 2 20  ? 111.029 113.556 147.495 1.00 39.86  ? 13  DC  C C2    1 
ATOM   2905 O  O2    . DC  B 2 20  ? 111.959 114.365 147.424 1.00 38.69  ? 13  DC  C O2    1 
ATOM   2906 N  N3    . DC  B 2 20  ? 110.954 112.471 146.687 1.00 38.25  ? 13  DC  C N3    1 
ATOM   2907 C  C4    . DC  B 2 20  ? 109.932 111.626 146.801 1.00 37.49  ? 13  DC  C C4    1 
ATOM   2908 N  N4    . DC  B 2 20  ? 109.895 110.569 145.987 1.00 35.51  ? 13  DC  C N4    1 
ATOM   2909 C  C5    . DC  B 2 20  ? 108.899 111.824 147.757 1.00 39.68  ? 13  DC  C C5    1 
ATOM   2910 C  C6    . DC  B 2 20  ? 108.982 112.897 148.544 1.00 42.69  ? 13  DC  C C6    1 
ATOM   2911 P  P     . DG  B 2 21  ? 109.037 119.074 150.839 1.00 66.87  ? 14  DG  C P     1 
ATOM   2912 O  OP1   . DG  B 2 21  ? 109.247 119.417 152.261 1.00 61.99  ? 14  DG  C OP1   1 
ATOM   2913 O  OP2   . DG  B 2 21  ? 107.672 119.053 150.278 1.00 49.03  ? 14  DG  C OP2   1 
ATOM   2914 O  "O5'" . DG  B 2 21  ? 109.905 120.053 149.926 1.00 60.64  ? 14  DG  C "O5'" 1 
ATOM   2915 C  "C5'" . DG  B 2 21  ? 111.297 119.838 149.783 1.00 51.70  ? 14  DG  C "C5'" 1 
ATOM   2916 C  "C4'" . DG  B 2 21  ? 111.738 120.127 148.361 1.00 52.20  ? 14  DG  C "C4'" 1 
ATOM   2917 O  "O4'" . DG  B 2 21  ? 111.521 118.953 147.533 1.00 52.56  ? 14  DG  C "O4'" 1 
ATOM   2918 C  "C3'" . DG  B 2 21  ? 110.992 121.269 147.678 1.00 53.57  ? 14  DG  C "C3'" 1 
ATOM   2919 O  "O3'" . DG  B 2 21  ? 111.893 122.026 146.899 1.00 61.88  ? 14  DG  C "O3'" 1 
ATOM   2920 C  "C2'" . DG  B 2 21  ? 109.975 120.540 146.806 1.00 47.11  ? 14  DG  C "C2'" 1 
ATOM   2921 C  "C1'" . DG  B 2 21  ? 110.761 119.307 146.401 1.00 48.57  ? 14  DG  C "C1'" 1 
ATOM   2922 N  N9    . DG  B 2 21  ? 109.920 118.171 146.038 1.00 45.34  ? 14  DG  C N9    1 
ATOM   2923 C  C8    . DG  B 2 21  ? 108.747 117.787 146.634 1.00 44.31  ? 14  DG  C C8    1 
ATOM   2924 N  N7    . DG  B 2 21  ? 108.215 116.726 146.096 1.00 38.64  ? 14  DG  C N7    1 
ATOM   2925 C  C5    . DG  B 2 21  ? 109.092 116.388 145.076 1.00 38.27  ? 14  DG  C C5    1 
ATOM   2926 C  C6    . DG  B 2 21  ? 109.037 115.327 144.147 1.00 40.33  ? 14  DG  C C6    1 
ATOM   2927 O  O6    . DG  B 2 21  ? 108.174 114.449 144.042 1.00 39.86  ? 14  DG  C O6    1 
ATOM   2928 N  N1    . DG  B 2 21  ? 110.126 115.343 143.283 1.00 40.14  ? 14  DG  C N1    1 
ATOM   2929 C  C2    . DG  B 2 21  ? 111.137 116.269 143.315 1.00 40.46  ? 14  DG  C C2    1 
ATOM   2930 N  N2    . DG  B 2 21  ? 112.106 116.127 142.400 1.00 44.50  ? 14  DG  C N2    1 
ATOM   2931 N  N3    . DG  B 2 21  ? 111.198 117.268 144.181 1.00 39.92  ? 14  DG  C N3    1 
ATOM   2932 C  C4    . DG  B 2 21  ? 110.146 117.265 145.028 1.00 40.15  ? 14  DG  C C4    1 
ATOM   2933 P  P     . DG  B 2 22  ? 111.724 123.617 146.783 1.00 84.19  ? 15  DG  C P     1 
ATOM   2934 O  OP1   . DG  B 2 22  ? 112.717 124.240 147.684 1.00 86.35  ? 15  DG  C OP1   1 
ATOM   2935 O  OP2   . DG  B 2 22  ? 110.287 123.935 146.928 1.00 73.15  ? 15  DG  C OP2   1 
ATOM   2936 O  "O5'" . DG  B 2 22  ? 112.145 123.925 145.276 1.00 61.15  ? 15  DG  C "O5'" 1 
ATOM   2937 C  "C5'" . DG  B 2 22  ? 113.380 123.438 144.782 1.00 56.10  ? 15  DG  C "C5'" 1 
ATOM   2938 C  "C4'" . DG  B 2 22  ? 113.263 123.051 143.320 1.00 53.50  ? 15  DG  C "C4'" 1 
ATOM   2939 O  "O4'" . DG  B 2 22  ? 112.470 121.839 143.191 1.00 50.37  ? 15  DG  C "O4'" 1 
ATOM   2940 C  "C3'" . DG  B 2 22  ? 112.583 124.088 142.425 1.00 50.65  ? 15  DG  C "C3'" 1 
ATOM   2941 O  "O3'" . DG  B 2 22  ? 113.260 124.153 141.180 1.00 49.46  ? 15  DG  C "O3'" 1 
ATOM   2942 C  "C2'" . DG  B 2 22  ? 111.179 123.513 142.268 1.00 42.36  ? 15  DG  C "C2'" 1 
ATOM   2943 C  "C1'" . DG  B 2 22  ? 111.506 122.039 142.189 1.00 44.30  ? 15  DG  C "C1'" 1 
ATOM   2944 N  N9    . DG  B 2 22  ? 110.370 121.164 142.440 1.00 46.89  ? 15  DG  C N9    1 
ATOM   2945 C  C8    . DG  B 2 22  ? 109.468 121.251 143.468 1.00 51.13  ? 15  DG  C C8    1 
ATOM   2946 N  N7    . DG  B 2 22  ? 108.554 120.322 143.433 1.00 48.92  ? 15  DG  C N7    1 
ATOM   2947 C  C5    . DG  B 2 22  ? 108.872 119.574 142.309 1.00 48.02  ? 15  DG  C C5    1 
ATOM   2948 C  C6    . DG  B 2 22  ? 108.238 118.436 141.762 1.00 45.20  ? 15  DG  C C6    1 
ATOM   2949 O  O6    . DG  B 2 22  ? 107.235 117.846 142.180 1.00 47.74  ? 15  DG  C O6    1 
ATOM   2950 N  N1    . DG  B 2 22  ? 108.884 117.986 140.615 1.00 38.31  ? 15  DG  C N1    1 
ATOM   2951 C  C2    . DG  B 2 22  ? 110.000 118.565 140.070 1.00 38.95  ? 15  DG  C C2    1 
ATOM   2952 N  N2    . DG  B 2 22  ? 110.487 117.997 138.961 1.00 35.55  ? 15  DG  C N2    1 
ATOM   2953 N  N3    . DG  B 2 22  ? 110.602 119.630 140.573 1.00 46.95  ? 15  DG  C N3    1 
ATOM   2954 C  C4    . DG  B 2 22  ? 109.986 120.079 141.689 1.00 46.75  ? 15  DG  C C4    1 
ATOM   2955 P  P     . DT  B 2 23  ? 113.028 125.396 140.193 1.00 54.74  ? 16  DT  C P     1 
ATOM   2956 O  OP1   . DT  B 2 23  ? 114.345 126.012 139.923 1.00 48.75  ? 16  DT  C OP1   1 
ATOM   2957 O  OP2   . DT  B 2 23  ? 111.928 126.205 140.757 1.00 60.33  ? 16  DT  C OP2   1 
ATOM   2958 O  "O5'" . DT  B 2 23  ? 112.503 124.723 138.847 1.00 47.18  ? 16  DT  C "O5'" 1 
ATOM   2959 C  "C5'" . DT  B 2 23  ? 111.374 123.874 138.880 1.00 41.56  ? 16  DT  C "C5'" 1 
ATOM   2960 C  "C4'" . DT  B 2 23  ? 111.269 123.069 137.606 1.00 39.82  ? 16  DT  C "C4'" 1 
ATOM   2961 O  "O4'" . DT  B 2 23  ? 110.502 121.868 137.859 1.00 36.80  ? 16  DT  C "O4'" 1 
ATOM   2962 C  "C3'" . DT  B 2 23  ? 110.562 123.779 136.468 1.00 47.41  ? 16  DT  C "C3'" 1 
ATOM   2963 O  "O3'" . DT  B 2 23  ? 111.078 123.354 135.223 1.00 47.92  ? 16  DT  C "O3'" 1 
ATOM   2964 C  "C2'" . DT  B 2 23  ? 109.120 123.343 136.655 1.00 49.06  ? 16  DT  C "C2'" 1 
ATOM   2965 C  "C1'" . DT  B 2 23  ? 109.281 121.916 137.160 1.00 42.32  ? 16  DT  C "C1'" 1 
ATOM   2966 N  N1    . DT  B 2 23  ? 108.203 121.516 138.083 1.00 44.68  ? 16  DT  C N1    1 
ATOM   2967 C  C2    . DT  B 2 23  ? 107.406 120.449 137.761 1.00 48.70  ? 16  DT  C C2    1 
ATOM   2968 O  O2    . DT  B 2 23  ? 107.550 119.791 136.748 1.00 50.66  ? 16  DT  C O2    1 
ATOM   2969 N  N3    . DT  B 2 23  ? 106.430 120.169 138.676 1.00 45.78  ? 16  DT  C N3    1 
ATOM   2970 C  C4    . DT  B 2 23  ? 106.174 120.842 139.853 1.00 44.96  ? 16  DT  C C4    1 
ATOM   2971 O  O4    . DT  B 2 23  ? 105.270 120.515 140.612 1.00 49.11  ? 16  DT  C O4    1 
ATOM   2972 C  C5    . DT  B 2 23  ? 107.043 121.957 140.127 1.00 43.28  ? 16  DT  C C5    1 
ATOM   2973 C  C7    . DT  B 2 23  ? 106.863 122.765 141.378 1.00 47.11  ? 16  DT  C C7    1 
ATOM   2974 C  C6    . DT  B 2 23  ? 108.003 122.239 139.238 1.00 43.15  ? 16  DT  C C6    1 
ATOM   2975 P  P     . DG  B 2 24  ? 111.138 124.386 133.996 1.00 62.42  ? 17  DG  C P     1 
ATOM   2976 O  OP1   . DG  B 2 24  ? 112.526 124.405 133.493 1.00 52.21  ? 17  DG  C OP1   1 
ATOM   2977 O  OP2   . DG  B 2 24  ? 110.498 125.640 134.443 1.00 60.37  ? 17  DG  C OP2   1 
ATOM   2978 O  "O5'" . DG  B 2 24  ? 110.181 123.737 132.895 1.00 52.74  ? 17  DG  C "O5'" 1 
ATOM   2979 C  "C5'" . DG  B 2 24  ? 110.613 122.612 132.147 1.00 51.09  ? 17  DG  C "C5'" 1 
ATOM   2980 C  "C4'" . DG  B 2 24  ? 109.502 122.109 131.245 1.00 49.68  ? 17  DG  C "C4'" 1 
ATOM   2981 O  "O4'" . DG  B 2 24  ? 108.442 121.551 132.061 1.00 55.26  ? 17  DG  C "O4'" 1 
ATOM   2982 C  "C3'" . DG  B 2 24  ? 108.850 123.172 130.367 1.00 54.52  ? 17  DG  C "C3'" 1 
ATOM   2983 O  "O3'" . DG  B 2 24  ? 108.544 122.634 129.090 1.00 61.24  ? 17  DG  C "O3'" 1 
ATOM   2984 C  "C2'" . DG  B 2 24  ? 107.592 123.548 131.141 1.00 57.14  ? 17  DG  C "C2'" 1 
ATOM   2985 C  "C1'" . DG  B 2 24  ? 107.236 122.248 131.848 1.00 62.11  ? 17  DG  C "C1'" 1 
ATOM   2986 N  N9    . DG  B 2 24  ? 106.600 122.471 133.138 1.00 61.35  ? 17  DG  C N9    1 
ATOM   2987 C  C8    . DG  B 2 24  ? 106.934 123.427 134.063 1.00 59.97  ? 17  DG  C C8    1 
ATOM   2988 N  N7    . DG  B 2 24  ? 106.189 123.398 135.129 1.00 56.70  ? 17  DG  C N7    1 
ATOM   2989 C  C5    . DG  B 2 24  ? 105.304 122.358 134.895 1.00 54.18  ? 17  DG  C C5    1 
ATOM   2990 C  C6    . DG  B 2 24  ? 104.261 121.859 135.700 1.00 57.12  ? 17  DG  C C6    1 
ATOM   2991 O  O6    . DG  B 2 24  ? 103.905 122.254 136.814 1.00 59.76  ? 17  DG  C O6    1 
ATOM   2992 N  N1    . DG  B 2 24  ? 103.602 120.797 135.092 1.00 59.14  ? 17  DG  C N1    1 
ATOM   2993 C  C2    . DG  B 2 24  ? 103.917 120.285 133.858 1.00 63.83  ? 17  DG  C C2    1 
ATOM   2994 N  N2    . DG  B 2 24  ? 103.170 119.258 133.432 1.00 68.05  ? 17  DG  C N2    1 
ATOM   2995 N  N3    . DG  B 2 24  ? 104.895 120.745 133.093 1.00 63.10  ? 17  DG  C N3    1 
ATOM   2996 C  C4    . DG  B 2 24  ? 105.542 121.779 133.674 1.00 58.49  ? 17  DG  C C4    1 
ATOM   2997 P  P     . DG  B 2 25  ? 107.777 123.522 127.992 1.00 63.54  ? 18  DG  C P     1 
ATOM   2998 O  OP1   . DG  B 2 25  ? 108.335 123.180 126.669 1.00 58.38  ? 18  DG  C OP1   1 
ATOM   2999 O  OP2   . DG  B 2 25  ? 107.784 124.935 128.426 1.00 62.01  ? 18  DG  C OP2   1 
ATOM   3000 O  "O5'" . DG  B 2 25  ? 106.280 122.973 128.053 1.00 69.70  ? 18  DG  C "O5'" 1 
ATOM   3001 C  "C5'" . DG  B 2 25  ? 106.046 121.575 127.948 1.00 64.96  ? 18  DG  C "C5'" 1 
ATOM   3002 C  "C4'" . DG  B 2 25  ? 104.575 121.250 128.124 1.00 67.40  ? 18  DG  C "C4'" 1 
ATOM   3003 O  "O4'" . DG  B 2 25  ? 104.175 121.501 129.498 1.00 64.88  ? 18  DG  C "O4'" 1 
ATOM   3004 C  "C3'" . DG  B 2 25  ? 103.625 122.068 127.252 1.00 80.33  ? 18  DG  C "C3'" 1 
ATOM   3005 O  "O3'" . DG  B 2 25  ? 102.589 121.233 126.769 1.00 90.95  ? 18  DG  C "O3'" 1 
ATOM   3006 C  "C2'" . DG  B 2 25  ? 103.092 123.115 128.225 1.00 79.81  ? 18  DG  C "C2'" 1 
ATOM   3007 C  "C1'" . DG  B 2 25  ? 103.020 122.307 129.506 1.00 75.48  ? 18  DG  C "C1'" 1 
ATOM   3008 N  N9    . DG  B 2 25  ? 103.025 123.117 130.720 1.00 76.22  ? 18  DG  C N9    1 
ATOM   3009 C  C8    . DG  B 2 25  ? 103.861 124.167 131.014 1.00 74.24  ? 18  DG  C C8    1 
ATOM   3010 N  N7    . DG  B 2 25  ? 103.634 124.698 132.183 1.00 67.57  ? 18  DG  C N7    1 
ATOM   3011 C  C5    . DG  B 2 25  ? 102.581 123.952 132.697 1.00 74.49  ? 18  DG  C C5    1 
ATOM   3012 C  C6    . DG  B 2 25  ? 101.902 124.065 133.932 1.00 77.80  ? 18  DG  C C6    1 
ATOM   3013 O  O6    . DG  B 2 25  ? 102.105 124.871 134.848 1.00 74.72  ? 18  DG  C O6    1 
ATOM   3014 N  N1    . DG  B 2 25  ? 100.896 123.109 134.058 1.00 82.58  ? 18  DG  C N1    1 
ATOM   3015 C  C2    . DG  B 2 25  ? 100.587 122.168 133.106 1.00 82.57  ? 18  DG  C C2    1 
ATOM   3016 N  N2    . DG  B 2 25  ? 99.582  121.332 133.404 1.00 82.78  ? 18  DG  C N2    1 
ATOM   3017 N  N3    . DG  B 2 25  ? 101.215 122.054 131.944 1.00 80.50  ? 18  DG  C N3    1 
ATOM   3018 C  C4    . DG  B 2 25  ? 102.197 122.975 131.809 1.00 76.85  ? 18  DG  C C4    1 
ATOM   3019 P  P     . DA  B 2 26  ? 101.879 121.548 125.364 1.00 100.28 ? 19  DA  C P     1 
ATOM   3020 O  OP1   . DA  B 2 26  ? 102.480 120.660 124.347 1.00 88.53  ? 19  DA  C OP1   1 
ATOM   3021 O  OP2   . DA  B 2 26  ? 101.895 123.013 125.166 1.00 97.52  ? 19  DA  C OP2   1 
ATOM   3022 O  "O5'" . DA  B 2 26  ? 100.364 121.098 125.603 1.00 101.39 ? 19  DA  C "O5'" 1 
ATOM   3023 C  "C5'" . DA  B 2 26  ? 100.085 119.791 126.084 1.00 100.04 ? 19  DA  C "C5'" 1 
ATOM   3024 C  "C4'" . DA  B 2 26  ? 98.793  119.763 126.882 1.00 103.76 ? 19  DA  C "C4'" 1 
ATOM   3025 O  "O4'" . DA  B 2 26  ? 98.952  120.528 128.102 1.00 95.85  ? 19  DA  C "O4'" 1 
ATOM   3026 C  "C3'" . DA  B 2 26  ? 97.576  120.343 126.175 1.00 109.45 ? 19  DA  C "C3'" 1 
ATOM   3027 O  "O3'" . DA  B 2 26  ? 96.424  119.592 126.521 1.00 111.86 ? 19  DA  C "O3'" 1 
ATOM   3028 C  "C2'" . DA  B 2 26  ? 97.508  121.772 126.712 1.00 103.08 ? 19  DA  C "C2'" 1 
ATOM   3029 C  "C1'" . DA  B 2 26  ? 98.043  121.611 128.129 1.00 97.72  ? 19  DA  C "C1'" 1 
ATOM   3030 N  N9    . DA  B 2 26  ? 98.761  122.781 128.619 1.00 93.76  ? 19  DA  C N9    1 
ATOM   3031 C  C8    . DA  B 2 26  ? 99.714  123.498 127.954 1.00 92.73  ? 19  DA  C C8    1 
ATOM   3032 N  N7    . DA  B 2 26  ? 100.205 124.497 128.647 1.00 89.78  ? 19  DA  C N7    1 
ATOM   3033 C  C5    . DA  B 2 26  ? 99.534  124.424 129.854 1.00 89.38  ? 19  DA  C C5    1 
ATOM   3034 C  C6    . DA  B 2 26  ? 99.599  125.205 131.024 1.00 86.45  ? 19  DA  C C6    1 
ATOM   3035 N  N6    . DA  B 2 26  ? 100.415 126.254 131.163 1.00 83.00  ? 19  DA  C N6    1 
ATOM   3036 N  N1    . DA  B 2 26  ? 98.791  124.865 132.048 1.00 87.47  ? 19  DA  C N1    1 
ATOM   3037 C  C2    . DA  B 2 26  ? 97.975  123.816 131.903 1.00 90.40  ? 19  DA  C C2    1 
ATOM   3038 N  N3    . DA  B 2 26  ? 97.826  123.008 130.856 1.00 92.75  ? 19  DA  C N3    1 
ATOM   3039 C  C4    . DA  B 2 26  ? 98.642  123.371 129.855 1.00 92.50  ? 19  DA  C C4    1 
ATOM   3040 P  P     . DT  B 2 27  ? 94.993  119.957 125.893 1.00 129.40 ? 20  DT  C P     1 
ATOM   3041 O  OP1   . DT  B 2 27  ? 94.249  118.691 125.719 1.00 119.91 ? 20  DT  C OP1   1 
ATOM   3042 O  OP2   . DT  B 2 27  ? 95.214  120.843 124.729 1.00 124.77 ? 20  DT  C OP2   1 
ATOM   3043 O  "O5'" . DT  B 2 27  ? 94.288  120.810 127.045 1.00 127.61 ? 20  DT  C "O5'" 1 
ATOM   3044 C  "C5'" . DT  B 2 27  ? 94.303  120.331 128.385 1.00 123.05 ? 20  DT  C "C5'" 1 
ATOM   3045 C  "C4'" . DT  B 2 27  ? 93.526  121.259 129.301 1.00 121.97 ? 20  DT  C "C4'" 1 
ATOM   3046 O  "O4'" . DT  B 2 27  ? 94.410  122.287 129.825 1.00 117.25 ? 20  DT  C "O4'" 1 
ATOM   3047 C  "C3'" . DT  B 2 27  ? 92.370  122.002 128.634 1.00 128.07 ? 20  DT  C "C3'" 1 
ATOM   3048 O  "O3'" . DT  B 2 27  ? 91.286  122.108 129.542 1.00 139.54 ? 20  DT  C "O3'" 1 
ATOM   3049 C  "C2'" . DT  B 2 27  ? 92.983  123.367 128.346 1.00 124.41 ? 20  DT  C "C2'" 1 
ATOM   3050 C  "C1'" . DT  B 2 27  ? 93.833  123.550 129.589 1.00 118.41 ? 20  DT  C "C1'" 1 
ATOM   3051 N  N1    . DT  B 2 27  ? 94.920  124.555 129.437 1.00 112.36 ? 20  DT  C N1    1 
ATOM   3052 C  C2    . DT  B 2 27  ? 95.242  125.358 130.505 1.00 114.18 ? 20  DT  C C2    1 
ATOM   3053 O  O2    . DT  B 2 27  ? 94.683  125.289 131.584 1.00 119.81 ? 20  DT  C O2    1 
ATOM   3054 N  N3    . DT  B 2 27  ? 96.250  126.250 130.268 1.00 108.33 ? 20  DT  C N3    1 
ATOM   3055 C  C4    . DT  B 2 27  ? 96.954  126.418 129.092 1.00 103.97 ? 20  DT  C C4    1 
ATOM   3056 O  O4    . DT  B 2 27  ? 97.847  127.250 128.978 1.00 104.77 ? 20  DT  C O4    1 
ATOM   3057 C  C5    . DT  B 2 27  ? 96.566  125.546 128.008 1.00 100.41 ? 20  DT  C C5    1 
ATOM   3058 C  C7    . DT  B 2 27  ? 97.259  125.636 126.681 1.00 95.38  ? 20  DT  C C7    1 
ATOM   3059 C  C6    . DT  B 2 27  ? 95.577  124.667 128.231 1.00 105.51 ? 20  DT  C C6    1 
ATOM   3060 P  P     . DG  B 2 28  ? 89.776  121.890 129.039 1.00 149.49 ? 21  DG  C P     1 
ATOM   3061 O  OP1   . DG  B 2 28  ? 89.511  120.436 129.034 1.00 144.00 ? 21  DG  C OP1   1 
ATOM   3062 O  OP2   . DG  B 2 28  ? 89.592  122.676 127.800 1.00 143.88 ? 21  DG  C OP2   1 
ATOM   3063 O  "O5'" . DG  B 2 28  ? 88.892  122.571 130.184 1.00 148.65 ? 21  DG  C "O5'" 1 
ATOM   3064 C  "C5'" . DG  B 2 28  ? 89.037  122.153 131.535 1.00 149.23 ? 21  DG  C "C5'" 1 
ATOM   3065 C  "C4'" . DG  B 2 28  ? 89.136  123.349 132.467 1.00 150.97 ? 21  DG  C "C4'" 1 
ATOM   3066 O  "O4'" . DG  B 2 28  ? 90.338  124.105 132.158 1.00 142.96 ? 21  DG  C "O4'" 1 
ATOM   3067 C  "C3'" . DG  B 2 28  ? 87.975  124.343 132.374 1.00 155.69 ? 21  DG  C "C3'" 1 
ATOM   3068 O  "O3'" . DG  B 2 28  ? 87.625  124.805 133.675 1.00 162.65 ? 21  DG  C "O3'" 1 
ATOM   3069 C  "C2'" . DG  B 2 28  ? 88.557  125.466 131.524 1.00 150.34 ? 21  DG  C "C2'" 1 
ATOM   3070 C  "C1'" . DG  B 2 28  ? 90.002  125.462 131.986 1.00 144.71 ? 21  DG  C "C1'" 1 
ATOM   3071 N  N9    . DG  B 2 28  ? 90.919  126.058 131.021 1.00 140.12 ? 21  DG  C N9    1 
ATOM   3072 C  C8    . DG  B 2 28  ? 91.074  125.712 129.703 1.00 138.48 ? 21  DG  C C8    1 
ATOM   3073 N  N7    . DG  B 2 28  ? 91.970  126.427 129.081 1.00 135.06 ? 21  DG  C N7    1 
ATOM   3074 C  C5    . DG  B 2 28  ? 92.433  127.306 130.049 1.00 134.15 ? 21  DG  C C5    1 
ATOM   3075 C  C6    . DG  B 2 28  ? 93.409  128.324 129.963 1.00 130.98 ? 21  DG  C C6    1 
ATOM   3076 O  O6    . DG  B 2 28  ? 94.084  128.660 128.982 1.00 127.41 ? 21  DG  C O6    1 
ATOM   3077 N  N1    . DG  B 2 28  ? 93.574  128.982 131.178 1.00 135.00 ? 21  DG  C N1    1 
ATOM   3078 C  C2    . DG  B 2 28  ? 92.880  128.692 132.328 1.00 140.22 ? 21  DG  C C2    1 
ATOM   3079 N  N2    . DG  B 2 28  ? 93.172  129.437 133.403 1.00 143.11 ? 21  DG  C N2    1 
ATOM   3080 N  N3    . DG  B 2 28  ? 91.963  127.742 132.420 1.00 141.40 ? 21  DG  C N3    1 
ATOM   3081 C  C4    . DG  B 2 28  ? 91.795  127.091 131.247 1.00 138.84 ? 21  DG  C C4    1 
ATOM   3082 P  P     . DC  B 2 29  ? 86.379  125.801 133.881 1.00 168.73 ? 22  DC  C P     1 
ATOM   3083 O  OP1   . DC  B 2 29  ? 85.639  125.324 135.069 1.00 167.74 ? 22  DC  C OP1   1 
ATOM   3084 O  OP2   . DC  B 2 29  ? 85.668  125.946 132.591 1.00 161.04 ? 22  DC  C OP2   1 
ATOM   3085 O  "O5'" . DC  B 2 29  ? 87.062  127.204 134.241 1.00 164.99 ? 22  DC  C "O5'" 1 
ATOM   3086 C  "C5'" . DC  B 2 29  ? 87.649  127.395 135.525 1.00 163.88 ? 22  DC  C "C5'" 1 
ATOM   3087 C  "C4'" . DC  B 2 29  ? 88.378  128.727 135.613 1.00 164.55 ? 22  DC  C "C4'" 1 
ATOM   3088 O  "O4'" . DC  B 2 29  ? 89.298  128.866 134.497 1.00 155.90 ? 22  DC  C "O4'" 1 
ATOM   3089 C  "C3'" . DC  B 2 29  ? 87.493  129.973 135.567 1.00 170.56 ? 22  DC  C "C3'" 1 
ATOM   3090 O  "O3'" . DC  B 2 29  ? 88.073  130.976 136.393 1.00 175.61 ? 22  DC  C "O3'" 1 
ATOM   3091 C  "C2'" . DC  B 2 29  ? 87.569  130.363 134.092 1.00 166.55 ? 22  DC  C "C2'" 1 
ATOM   3092 C  "C1'" . DC  B 2 29  ? 89.033  130.083 133.832 1.00 160.08 ? 22  DC  C "C1'" 1 
ATOM   3093 N  N1    . DC  B 2 29  ? 89.404  129.918 132.405 1.00 155.77 ? 22  DC  C N1    1 
ATOM   3094 C  C2    . DC  B 2 29  ? 90.390  130.741 131.857 1.00 155.53 ? 22  DC  C C2    1 
ATOM   3095 O  O2    . DC  B 2 29  ? 90.906  131.610 132.565 1.00 157.36 ? 22  DC  C O2    1 
ATOM   3096 N  N3    . DC  B 2 29  ? 90.747  130.564 130.561 1.00 153.35 ? 22  DC  C N3    1 
ATOM   3097 C  C4    . DC  B 2 29  ? 90.165  129.614 129.833 1.00 151.69 ? 22  DC  C C4    1 
ATOM   3098 N  N4    . DC  B 2 29  ? 90.553  129.481 128.559 1.00 149.17 ? 22  DC  C N4    1 
ATOM   3099 C  C5    . DC  B 2 29  ? 89.163  128.759 130.376 1.00 151.68 ? 22  DC  C C5    1 
ATOM   3100 C  C6    . DC  B 2 29  ? 88.822  128.939 131.656 1.00 154.40 ? 22  DC  C C6    1 
ATOM   3101 P  P     . DG  B 2 30  ? 87.193  132.191 136.967 1.00 180.16 ? 23  DG  C P     1 
ATOM   3102 O  OP1   . DG  B 2 30  ? 86.400  131.676 138.105 1.00 177.52 ? 23  DG  C OP1   1 
ATOM   3103 O  OP2   . DG  B 2 30  ? 86.509  132.841 135.829 1.00 176.23 ? 23  DG  C OP2   1 
ATOM   3104 O  "O5'" . DG  B 2 30  ? 88.292  133.214 137.522 1.00 178.53 ? 23  DG  C "O5'" 1 
ATOM   3105 C  "C5'" . DG  B 2 30  ? 89.525  133.382 136.820 1.00 176.41 ? 23  DG  C "C5'" 1 
ATOM   3106 C  "C4'" . DG  B 2 30  ? 89.988  134.826 136.870 1.00 180.21 ? 23  DG  C "C4'" 1 
ATOM   3107 O  "O4'" . DG  B 2 30  ? 90.483  135.211 135.567 1.00 178.14 ? 23  DG  C "O4'" 1 
ATOM   3108 C  "C3'" . DG  B 2 30  ? 88.890  135.826 137.139 1.00 185.78 ? 23  DG  C "C3'" 1 
ATOM   3109 O  "O3'" . DG  B 2 30  ? 89.459  137.076 137.517 1.00 189.51 ? 23  DG  C "O3'" 1 
ATOM   3110 C  "C2'" . DG  B 2 30  ? 88.230  135.903 135.769 1.00 185.38 ? 23  DG  C "C2'" 1 
ATOM   3111 C  "C1'" . DG  B 2 30  ? 89.431  135.815 134.827 1.00 181.04 ? 23  DG  C "C1'" 1 
ATOM   3112 N  N9    . DG  B 2 30  ? 89.189  134.993 133.643 1.00 175.84 ? 23  DG  C N9    1 
ATOM   3113 C  C8    . DG  B 2 30  ? 88.374  133.891 133.554 1.00 172.72 ? 23  DG  C C8    1 
ATOM   3114 N  N7    . DG  B 2 30  ? 88.371  133.341 132.372 1.00 170.65 ? 23  DG  C N7    1 
ATOM   3115 C  C5    . DG  B 2 30  ? 89.243  134.125 131.629 1.00 171.41 ? 23  DG  C C5    1 
ATOM   3116 C  C6    . DG  B 2 30  ? 89.640  134.013 130.276 1.00 169.28 ? 23  DG  C C6    1 
ATOM   3117 O  O6    . DG  B 2 30  ? 89.288  133.170 129.440 1.00 165.88 ? 23  DG  C O6    1 
ATOM   3118 N  N1    . DG  B 2 30  ? 90.539  135.016 129.918 1.00 169.81 ? 23  DG  C N1    1 
ATOM   3119 C  C2    . DG  B 2 30  ? 90.997  135.999 130.763 1.00 174.29 ? 23  DG  C C2    1 
ATOM   3120 N  N2    . DG  B 2 30  ? 91.868  136.873 130.240 1.00 173.69 ? 23  DG  C N2    1 
ATOM   3121 N  N3    . DG  B 2 30  ? 90.637  136.111 132.036 1.00 176.75 ? 23  DG  C N3    1 
ATOM   3122 C  C4    . DG  B 2 30  ? 89.759  135.144 132.398 1.00 175.28 ? 23  DG  C C4    1 
ATOM   3123 P  P     . DT  B 2 31  ? 88.517  138.336 137.849 1.00 193.49 ? 24  DT  C P     1 
ATOM   3124 O  OP1   . DT  B 2 31  ? 89.100  139.017 139.025 1.00 194.22 ? 24  DT  C OP1   1 
ATOM   3125 O  OP2   . DT  B 2 31  ? 87.112  137.875 137.902 1.00 186.36 ? 24  DT  C OP2   1 
ATOM   3126 O  "O5'" . DT  B 2 31  ? 88.690  139.287 136.573 1.00 193.22 ? 24  DT  C "O5'" 1 
ATOM   3127 C  "C5'" . DT  B 2 31  ? 89.946  139.916 136.321 1.00 192.28 ? 24  DT  C "C5'" 1 
ATOM   3128 C  "C4'" . DT  B 2 31  ? 89.971  140.568 134.946 1.00 194.13 ? 24  DT  C "C4'" 1 
ATOM   3129 O  "O4'" . DT  B 2 31  ? 89.626  139.584 133.934 1.00 190.57 ? 24  DT  C "O4'" 1 
ATOM   3130 C  "C3'" . DT  B 2 31  ? 88.999  141.727 134.756 1.00 197.29 ? 24  DT  C "C3'" 1 
ATOM   3131 O  "O3'" . DT  B 2 31  ? 89.611  142.761 133.926 1.00 201.84 ? 24  DT  C "O3'" 1 
ATOM   3132 C  "C2'" . DT  B 2 31  ? 87.788  141.050 134.096 1.00 196.18 ? 24  DT  C "C2'" 1 
ATOM   3133 C  "C1'" . DT  B 2 31  ? 88.456  139.978 133.242 1.00 192.68 ? 24  DT  C "C1'" 1 
ATOM   3134 N  N1    . DT  B 2 31  ? 87.629  138.762 133.003 1.00 188.10 ? 24  DT  C N1    1 
ATOM   3135 C  C2    . DT  B 2 31  ? 87.810  138.055 131.838 1.00 184.12 ? 24  DT  C C2    1 
ATOM   3136 O  O2    . DT  B 2 31  ? 88.599  138.387 130.974 1.00 181.67 ? 24  DT  C O2    1 
ATOM   3137 N  N3    . DT  B 2 31  ? 87.026  136.939 131.717 1.00 182.61 ? 24  DT  C N3    1 
ATOM   3138 C  C4    . DT  B 2 31  ? 86.101  136.466 132.628 1.00 181.93 ? 24  DT  C C4    1 
ATOM   3139 O  O4    . DT  B 2 31  ? 85.442  135.451 132.428 1.00 179.43 ? 24  DT  C O4    1 
ATOM   3140 C  C5    . DT  B 2 31  ? 85.961  137.253 133.830 1.00 184.11 ? 24  DT  C C5    1 
ATOM   3141 C  C7    . DT  B 2 31  ? 84.987  136.837 134.893 1.00 181.22 ? 24  DT  C C7    1 
ATOM   3142 C  C6    . DT  B 2 31  ? 86.727  138.349 133.961 1.00 186.49 ? 24  DT  C C6    1 
ATOM   3143 P  P     . DG  B 2 32  ? 88.833  143.383 132.663 1.00 209.24 ? 25  DG  C P     1 
ATOM   3144 O  OP1   . DG  B 2 32  ? 87.550  143.953 133.135 1.00 201.15 ? 25  DG  C OP1   1 
ATOM   3145 O  OP2   . DG  B 2 32  ? 88.927  142.363 131.602 1.00 202.07 ? 25  DG  C OP2   1 
ATOM   3146 O  "O5'" . DG  B 2 32  ? 89.742  144.592 132.141 1.00 205.71 ? 25  DG  C "O5'" 1 
ATOM   3147 C  "C5'" . DG  B 2 32  ? 90.505  144.450 130.928 1.00 200.65 ? 25  DG  C "C5'" 1 
ATOM   3148 C  "C4'" . DG  B 2 32  ? 89.669  144.703 129.665 1.00 196.09 ? 25  DG  C "C4'" 1 
ATOM   3149 O  "O4'" . DG  B 2 32  ? 88.896  143.522 129.315 1.00 193.84 ? 25  DG  C "O4'" 1 
ATOM   3150 C  "C3'" . DG  B 2 32  ? 88.663  145.848 129.722 1.00 198.99 ? 25  DG  C "C3'" 1 
ATOM   3151 O  "O3'" . DG  B 2 32  ? 88.562  146.425 128.432 1.00 200.43 ? 25  DG  C "O3'" 1 
ATOM   3152 C  "C2'" . DG  B 2 32  ? 87.374  145.125 130.092 1.00 196.48 ? 25  DG  C "C2'" 1 
ATOM   3153 C  "C1'" . DG  B 2 32  ? 87.518  143.849 129.276 1.00 195.33 ? 25  DG  C "C1'" 1 
ATOM   3154 N  N9    . DG  B 2 32  ? 86.755  142.721 129.805 1.00 195.07 ? 25  DG  C N9    1 
ATOM   3155 C  C8    . DG  B 2 32  ? 86.132  142.634 131.027 1.00 195.31 ? 25  DG  C C8    1 
ATOM   3156 N  N7    . DG  B 2 32  ? 85.533  141.493 131.227 1.00 193.17 ? 25  DG  C N7    1 
ATOM   3157 C  C5    . DG  B 2 32  ? 85.757  140.785 130.057 1.00 191.95 ? 25  DG  C C5    1 
ATOM   3158 C  C6    . DG  B 2 32  ? 85.341  139.486 129.683 1.00 189.46 ? 25  DG  C C6    1 
ATOM   3159 O  O6    . DG  B 2 32  ? 84.669  138.672 130.333 1.00 188.55 ? 25  DG  C O6    1 
ATOM   3160 N  N1    . DG  B 2 32  ? 85.786  139.158 128.408 1.00 189.46 ? 25  DG  C N1    1 
ATOM   3161 C  C2    . DG  B 2 32  ? 86.539  139.975 127.602 1.00 188.59 ? 25  DG  C C2    1 
ATOM   3162 N  N2    . DG  B 2 32  ? 86.860  139.475 126.404 1.00 186.79 ? 25  DG  C N2    1 
ATOM   3163 N  N3    . DG  B 2 32  ? 86.930  141.191 127.934 1.00 189.88 ? 25  DG  C N3    1 
ATOM   3164 C  C4    . DG  B 2 32  ? 86.507  141.530 129.172 1.00 192.62 ? 25  DG  C C4    1 
ATOM   3165 P  P     . DG  B 2 33  ? 87.876  147.861 128.213 1.00 201.84 ? 26  DG  C P     1 
ATOM   3166 O  OP1   . DG  B 2 33  ? 88.902  148.885 128.510 1.00 200.25 ? 26  DG  C OP1   1 
ATOM   3167 O  OP2   . DG  B 2 33  ? 86.583  147.885 128.932 1.00 196.49 ? 26  DG  C OP2   1 
ATOM   3168 O  "O5'" . DG  B 2 33  ? 87.565  147.880 126.646 1.00 197.09 ? 26  DG  C "O5'" 1 
ATOM   3169 C  "C5'" . DG  B 2 33  ? 88.559  147.446 125.723 1.00 191.80 ? 26  DG  C "C5'" 1 
ATOM   3170 C  "C4'" . DG  B 2 33  ? 87.953  146.572 124.637 1.00 188.08 ? 26  DG  C "C4'" 1 
ATOM   3171 O  "O4'" . DG  B 2 33  ? 87.331  145.407 125.238 1.00 189.01 ? 26  DG  C "O4'" 1 
ATOM   3172 C  "C3'" . DG  B 2 33  ? 86.873  147.247 123.788 1.00 186.03 ? 26  DG  C "C3'" 1 
ATOM   3173 O  "O3'" . DG  B 2 33  ? 87.099  146.978 122.410 1.00 180.15 ? 26  DG  C "O3'" 1 
ATOM   3174 C  "C2'" . DG  B 2 33  ? 85.577  146.602 124.280 1.00 186.62 ? 26  DG  C "C2'" 1 
ATOM   3175 C  "C1'" . DG  B 2 33  ? 86.056  145.216 124.674 1.00 187.97 ? 26  DG  C "C1'" 1 
ATOM   3176 N  N9    . DG  B 2 33  ? 85.205  144.567 125.666 1.00 189.55 ? 26  DG  C N9    1 
ATOM   3177 C  C8    . DG  B 2 33  ? 84.672  145.136 126.796 1.00 189.71 ? 26  DG  C C8    1 
ATOM   3178 N  N7    . DG  B 2 33  ? 83.947  144.313 127.500 1.00 188.54 ? 26  DG  C N7    1 
ATOM   3179 C  C5    . DG  B 2 33  ? 84.003  143.120 126.793 1.00 190.26 ? 26  DG  C C5    1 
ATOM   3180 C  C6    . DG  B 2 33  ? 83.407  141.867 127.072 1.00 191.19 ? 26  DG  C C6    1 
ATOM   3181 O  O6    . DG  B 2 33  ? 82.690  141.556 128.032 1.00 189.20 ? 26  DG  C O6    1 
ATOM   3182 N  N1    . DG  B 2 33  ? 83.716  140.921 126.097 1.00 193.49 ? 26  DG  C N1    1 
ATOM   3183 C  C2    . DG  B 2 33  ? 84.500  141.157 124.993 1.00 192.01 ? 26  DG  C C2    1 
ATOM   3184 N  N2    . DG  B 2 33  ? 84.685  140.119 124.164 1.00 188.67 ? 26  DG  C N2    1 
ATOM   3185 N  N3    . DG  B 2 33  ? 85.065  142.327 124.720 1.00 191.07 ? 26  DG  C N3    1 
ATOM   3186 C  C4    . DG  B 2 33  ? 84.773  143.259 125.660 1.00 190.92 ? 26  DG  C C4    1 
ATOM   3187 N  N     . PRO C 1 2   ? 120.841 119.847 115.787 1.00 60.18  ? 2   PRO B N     1 
ATOM   3188 C  CA    . PRO C 1 2   ? 121.490 118.567 115.494 1.00 64.02  ? 2   PRO B CA    1 
ATOM   3189 C  C     . PRO C 1 2   ? 121.690 117.732 116.750 1.00 61.74  ? 2   PRO B C     1 
ATOM   3190 O  O     . PRO C 1 2   ? 121.528 118.251 117.851 1.00 60.32  ? 2   PRO B O     1 
ATOM   3191 C  CB    . PRO C 1 2   ? 122.841 118.981 114.897 1.00 64.63  ? 2   PRO B CB    1 
ATOM   3192 C  CG    . PRO C 1 2   ? 122.672 120.407 114.497 1.00 67.69  ? 2   PRO B CG    1 
ATOM   3193 C  CD    . PRO C 1 2   ? 121.722 120.985 115.488 1.00 61.79  ? 2   PRO B CD    1 
ATOM   3194 N  N     . PHE C 1 3   ? 122.034 116.455 116.580 1.00 60.23  ? 3   PHE B N     1 
ATOM   3195 C  CA    . PHE C 1 3   ? 122.292 115.596 117.731 1.00 52.85  ? 3   PHE B CA    1 
ATOM   3196 C  C     . PHE C 1 3   ? 123.467 116.123 118.546 1.00 60.03  ? 3   PHE B C     1 
ATOM   3197 O  O     . PHE C 1 3   ? 123.313 116.501 119.712 1.00 66.09  ? 3   PHE B O     1 
ATOM   3198 C  CB    . PHE C 1 3   ? 122.551 114.164 117.264 1.00 46.57  ? 3   PHE B CB    1 
ATOM   3199 C  CG    . PHE C 1 3   ? 122.464 113.144 118.358 1.00 51.78  ? 3   PHE B CG    1 
ATOM   3200 C  CD1   . PHE C 1 3   ? 121.319 113.024 119.121 1.00 51.51  ? 3   PHE B CD1   1 
ATOM   3201 C  CD2   . PHE C 1 3   ? 123.527 112.299 118.618 1.00 57.02  ? 3   PHE B CD2   1 
ATOM   3202 C  CE1   . PHE C 1 3   ? 121.238 112.084 120.126 1.00 56.58  ? 3   PHE B CE1   1 
ATOM   3203 C  CE2   . PHE C 1 3   ? 123.449 111.359 119.620 1.00 56.94  ? 3   PHE B CE2   1 
ATOM   3204 C  CZ    . PHE C 1 3   ? 122.304 111.251 120.375 1.00 54.80  ? 3   PHE B CZ    1 
ATOM   3205 N  N     . THR C 1 4   ? 124.651 116.159 117.944 1.00 56.20  ? 4   THR B N     1 
ATOM   3206 C  CA    . THR C 1 4   ? 125.798 116.768 118.600 1.00 53.60  ? 4   THR B CA    1 
ATOM   3207 C  C     . THR C 1 4   ? 125.669 118.284 118.562 1.00 53.79  ? 4   THR B C     1 
ATOM   3208 O  O     . THR C 1 4   ? 125.176 118.855 117.586 1.00 58.94  ? 4   THR B O     1 
ATOM   3209 C  CB    . THR C 1 4   ? 127.096 116.330 117.927 1.00 56.34  ? 4   THR B CB    1 
ATOM   3210 O  OG1   . THR C 1 4   ? 126.971 114.975 117.481 1.00 60.33  ? 4   THR B OG1   1 
ATOM   3211 C  CG2   . THR C 1 4   ? 128.255 116.427 118.903 1.00 58.89  ? 4   THR B CG2   1 
ATOM   3212 N  N     . TYR C 1 5   ? 126.107 118.935 119.636 1.00 54.14  ? 5   TYR B N     1 
ATOM   3213 C  CA    . TYR C 1 5   ? 125.948 120.379 119.747 1.00 58.44  ? 5   TYR B CA    1 
ATOM   3214 C  C     . TYR C 1 5   ? 126.767 121.095 118.681 1.00 63.63  ? 5   TYR B C     1 
ATOM   3215 O  O     . TYR C 1 5   ? 127.946 120.795 118.478 1.00 65.33  ? 5   TYR B O     1 
ATOM   3216 C  CB    . TYR C 1 5   ? 126.367 120.849 121.138 1.00 58.32  ? 5   TYR B CB    1 
ATOM   3217 C  CG    . TYR C 1 5   ? 126.167 122.328 121.363 1.00 60.05  ? 5   TYR B CG    1 
ATOM   3218 C  CD1   . TYR C 1 5   ? 124.913 122.904 121.238 1.00 56.01  ? 5   TYR B CD1   1 
ATOM   3219 C  CD2   . TYR C 1 5   ? 127.234 123.150 121.690 1.00 63.84  ? 5   TYR B CD2   1 
ATOM   3220 C  CE1   . TYR C 1 5   ? 124.727 124.255 121.439 1.00 54.76  ? 5   TYR B CE1   1 
ATOM   3221 C  CE2   . TYR C 1 5   ? 127.056 124.503 121.891 1.00 62.71  ? 5   TYR B CE2   1 
ATOM   3222 C  CZ    . TYR C 1 5   ? 125.801 125.049 121.764 1.00 59.79  ? 5   TYR B CZ    1 
ATOM   3223 O  OH    . TYR C 1 5   ? 125.623 126.397 121.965 1.00 66.65  ? 5   TYR B OH    1 
ATOM   3224 N  N     . SER C 1 6   ? 126.133 122.047 118.000 1.00 60.52  ? 6   SER B N     1 
ATOM   3225 C  CA    . SER C 1 6   ? 126.779 122.842 116.965 1.00 59.88  ? 6   SER B CA    1 
ATOM   3226 C  C     . SER C 1 6   ? 126.520 124.315 117.239 1.00 60.07  ? 6   SER B C     1 
ATOM   3227 O  O     . SER C 1 6   ? 125.371 124.717 117.444 1.00 58.95  ? 6   SER B O     1 
ATOM   3228 C  CB    . SER C 1 6   ? 126.265 122.462 115.576 1.00 58.17  ? 6   SER B CB    1 
ATOM   3229 O  OG    . SER C 1 6   ? 124.857 122.577 115.516 1.00 57.76  ? 6   SER B OG    1 
ATOM   3230 N  N     . ILE C 1 7   ? 127.589 125.113 117.235 1.00 56.78  ? 7   ILE B N     1 
ATOM   3231 C  CA    . ILE C 1 7   ? 127.469 126.526 117.584 1.00 55.80  ? 7   ILE B CA    1 
ATOM   3232 C  C     . ILE C 1 7   ? 126.692 127.286 116.517 1.00 62.04  ? 7   ILE B C     1 
ATOM   3233 O  O     . ILE C 1 7   ? 125.852 128.138 116.831 1.00 67.75  ? 7   ILE B O     1 
ATOM   3234 C  CB    . ILE C 1 7   ? 128.864 127.134 117.813 1.00 46.55  ? 7   ILE B CB    1 
ATOM   3235 C  CG1   . ILE C 1 7   ? 129.507 126.529 119.059 1.00 51.87  ? 7   ILE B CG1   1 
ATOM   3236 C  CG2   . ILE C 1 7   ? 128.775 128.641 117.947 1.00 50.10  ? 7   ILE B CG2   1 
ATOM   3237 C  CD1   . ILE C 1 7   ? 130.524 125.453 118.763 1.00 61.60  ? 7   ILE B CD1   1 
ATOM   3238 N  N     . GLU C 1 8   ? 126.958 126.997 115.241 1.00 59.31  ? 8   GLU B N     1 
ATOM   3239 C  CA    . GLU C 1 8   ? 126.319 127.744 114.163 1.00 57.73  ? 8   GLU B CA    1 
ATOM   3240 C  C     . GLU C 1 8   ? 124.810 127.538 114.155 1.00 61.77  ? 8   GLU B C     1 
ATOM   3241 O  O     . GLU C 1 8   ? 124.047 128.494 113.971 1.00 67.85  ? 8   GLU B O     1 
ATOM   3242 C  CB    . GLU C 1 8   ? 126.921 127.341 112.818 1.00 58.79  ? 8   GLU B CB    1 
ATOM   3243 C  CG    . GLU C 1 8   ? 128.344 127.823 112.606 1.00 69.95  ? 8   GLU B CG    1 
ATOM   3244 C  CD    . GLU C 1 8   ? 128.514 129.300 112.901 1.00 77.95  ? 8   GLU B CD    1 
ATOM   3245 O  OE1   . GLU C 1 8   ? 127.837 130.120 112.246 1.00 79.13  ? 8   GLU B OE1   1 
ATOM   3246 O  OE2   . GLU C 1 8   ? 129.329 129.644 113.783 1.00 78.49  ? 8   GLU B OE2   1 
ATOM   3247 N  N     . ALA C 1 9   ? 124.356 126.299 114.349 1.00 59.75  ? 9   ALA B N     1 
ATOM   3248 C  CA    . ALA C 1 9   ? 122.922 126.032 114.321 1.00 61.52  ? 9   ALA B CA    1 
ATOM   3249 C  C     . ALA C 1 9   ? 122.216 126.669 115.510 1.00 65.55  ? 9   ALA B C     1 
ATOM   3250 O  O     . ALA C 1 9   ? 121.084 127.149 115.381 1.00 71.20  ? 9   ALA B O     1 
ATOM   3251 C  CB    . ALA C 1 9   ? 122.663 124.527 114.286 1.00 57.77  ? 9   ALA B CB    1 
ATOM   3252 N  N     . THR C 1 10  ? 122.861 126.675 116.678 1.00 63.41  ? 10  THR B N     1 
ATOM   3253 C  CA    . THR C 1 10  ? 122.291 127.362 117.832 1.00 65.46  ? 10  THR B CA    1 
ATOM   3254 C  C     . THR C 1 10  ? 122.211 128.863 117.588 1.00 64.38  ? 10  THR B C     1 
ATOM   3255 O  O     . THR C 1 10  ? 121.212 129.506 117.932 1.00 64.84  ? 10  THR B O     1 
ATOM   3256 C  CB    . THR C 1 10  ? 123.115 127.058 119.084 1.00 63.57  ? 10  THR B CB    1 
ATOM   3257 O  OG1   . THR C 1 10  ? 122.717 125.791 119.619 1.00 66.57  ? 10  THR B OG1   1 
ATOM   3258 C  CG2   . THR C 1 10  ? 122.911 128.130 120.141 1.00 59.19  ? 10  THR B CG2   1 
ATOM   3259 N  N     . ARG C 1 11  ? 123.253 129.438 116.982 1.00 63.10  ? 11  ARG B N     1 
ATOM   3260 C  CA    . ARG C 1 11  ? 123.234 130.861 116.665 1.00 65.66  ? 11  ARG B CA    1 
ATOM   3261 C  C     . ARG C 1 11  ? 122.126 131.190 115.671 1.00 67.67  ? 11  ARG B C     1 
ATOM   3262 O  O     . ARG C 1 11  ? 121.476 132.237 115.777 1.00 70.47  ? 11  ARG B O     1 
ATOM   3263 C  CB    . ARG C 1 11  ? 124.595 131.290 116.119 1.00 67.14  ? 11  ARG B CB    1 
ATOM   3264 C  CG    . ARG C 1 11  ? 124.651 132.725 115.630 1.00 72.46  ? 11  ARG B CG    1 
ATOM   3265 C  CD    . ARG C 1 11  ? 125.999 133.045 115.006 1.00 80.08  ? 11  ARG B CD    1 
ATOM   3266 N  NE    . ARG C 1 11  ? 125.982 132.877 113.558 1.00 89.69  ? 11  ARG B NE    1 
ATOM   3267 C  CZ    . ARG C 1 11  ? 126.361 133.806 112.693 1.00 93.36  ? 11  ARG B CZ    1 
ATOM   3268 N  NH1   . ARG C 1 11  ? 126.794 134.990 113.095 1.00 95.25  ? 11  ARG B NH1   1 
ATOM   3269 N  NH2   . ARG C 1 11  ? 126.302 133.543 111.390 1.00 85.83  ? 11  ARG B NH2   1 
ATOM   3270 N  N     . ASN C 1 12  ? 121.893 130.306 114.699 1.00 67.82  ? 12  ASN B N     1 
ATOM   3271 C  CA    . ASN C 1 12  ? 120.860 130.540 113.697 1.00 66.24  ? 12  ASN B CA    1 
ATOM   3272 C  C     . ASN C 1 12  ? 119.449 130.349 114.237 1.00 66.58  ? 12  ASN B C     1 
ATOM   3273 O  O     . ASN C 1 12  ? 118.491 130.722 113.551 1.00 67.70  ? 12  ASN B O     1 
ATOM   3274 C  CB    . ASN C 1 12  ? 121.076 129.618 112.496 1.00 67.01  ? 12  ASN B CB    1 
ATOM   3275 C  CG    . ASN C 1 12  ? 122.268 130.027 111.656 1.00 75.18  ? 12  ASN B CG    1 
ATOM   3276 O  OD1   . ASN C 1 12  ? 122.851 131.090 111.860 1.00 73.05  ? 12  ASN B OD1   1 
ATOM   3277 N  ND2   . ASN C 1 12  ? 122.637 129.180 110.703 1.00 78.66  ? 12  ASN B ND2   1 
ATOM   3278 N  N     . LEU C 1 13  ? 119.294 129.781 115.429 1.00 70.37  ? 13  LEU B N     1 
ATOM   3279 C  CA    . LEU C 1 13  ? 117.970 129.582 116.000 1.00 71.41  ? 13  LEU B CA    1 
ATOM   3280 C  C     . LEU C 1 13  ? 117.336 130.916 116.377 1.00 76.37  ? 13  LEU B C     1 
ATOM   3281 O  O     . LEU C 1 13  ? 118.019 131.872 116.753 1.00 81.68  ? 13  LEU B O     1 
ATOM   3282 C  CB    . LEU C 1 13  ? 118.045 128.684 117.233 1.00 66.07  ? 13  LEU B CB    1 
ATOM   3283 C  CG    . LEU C 1 13  ? 118.014 127.174 117.003 1.00 65.84  ? 13  LEU B CG    1 
ATOM   3284 C  CD1   . LEU C 1 13  ? 117.884 126.440 118.326 1.00 61.99  ? 13  LEU B CD1   1 
ATOM   3285 C  CD2   . LEU C 1 13  ? 116.886 126.795 116.063 1.00 75.38  ? 13  LEU B CD2   1 
ATOM   3286 N  N     . ALA C 1 14  ? 116.012 130.973 116.273 1.00 71.30  ? 14  ALA B N     1 
ATOM   3287 C  CA    . ALA C 1 14  ? 115.283 132.162 116.682 1.00 72.82  ? 14  ALA B CA    1 
ATOM   3288 C  C     . ALA C 1 14  ? 115.287 132.290 118.202 1.00 79.40  ? 14  ALA B C     1 
ATOM   3289 O  O     . ALA C 1 14  ? 115.565 131.337 118.933 1.00 82.16  ? 14  ALA B O     1 
ATOM   3290 C  CB    . ALA C 1 14  ? 113.848 132.120 116.160 1.00 73.33  ? 14  ALA B CB    1 
ATOM   3291 N  N     . THR C 1 15  ? 114.979 133.499 118.677 1.00 80.15  ? 15  THR B N     1 
ATOM   3292 C  CA    . THR C 1 15  ? 114.990 133.754 120.114 1.00 81.16  ? 15  THR B CA    1 
ATOM   3293 C  C     . THR C 1 15  ? 113.928 132.928 120.832 1.00 79.59  ? 15  THR B C     1 
ATOM   3294 O  O     . THR C 1 15  ? 114.177 132.387 121.916 1.00 76.35  ? 15  THR B O     1 
ATOM   3295 C  CB    . THR C 1 15  ? 114.789 135.247 120.382 1.00 82.36  ? 15  THR B CB    1 
ATOM   3296 O  OG1   . THR C 1 15  ? 116.038 135.932 120.222 1.00 86.82  ? 15  THR B OG1   1 
ATOM   3297 C  CG2   . THR C 1 15  ? 114.274 135.483 121.793 1.00 79.54  ? 15  THR B CG2   1 
ATOM   3298 N  N     . THR C 1 16  ? 112.744 132.802 120.236 1.00 79.26  ? 16  THR B N     1 
ATOM   3299 C  CA    . THR C 1 16  ? 111.660 132.034 120.835 1.00 74.32  ? 16  THR B CA    1 
ATOM   3300 C  C     . THR C 1 16  ? 111.756 130.542 120.549 1.00 71.57  ? 16  THR B C     1 
ATOM   3301 O  O     . THR C 1 16  ? 110.893 129.786 121.006 1.00 75.15  ? 16  THR B O     1 
ATOM   3302 C  CB    . THR C 1 16  ? 110.308 132.554 120.344 1.00 77.97  ? 16  THR B CB    1 
ATOM   3303 O  OG1   . THR C 1 16  ? 109.287 131.598 120.655 1.00 75.73  ? 16  THR B OG1   1 
ATOM   3304 C  CG2   . THR C 1 16  ? 110.339 132.783 118.843 1.00 79.97  ? 16  THR B CG2   1 
ATOM   3305 N  N     . GLU C 1 17  ? 112.770 130.103 119.805 1.00 70.38  ? 17  GLU B N     1 
ATOM   3306 C  CA    . GLU C 1 17  ? 112.945 128.699 119.461 1.00 68.40  ? 17  GLU B CA    1 
ATOM   3307 C  C     . GLU C 1 17  ? 114.123 128.061 120.184 1.00 67.54  ? 17  GLU B C     1 
ATOM   3308 O  O     . GLU C 1 17  ? 114.468 126.912 119.893 1.00 65.85  ? 17  GLU B O     1 
ATOM   3309 C  CB    . GLU C 1 17  ? 113.124 128.551 117.949 1.00 73.44  ? 17  GLU B CB    1 
ATOM   3310 C  CG    . GLU C 1 17  ? 112.220 127.522 117.306 1.00 82.41  ? 17  GLU B CG    1 
ATOM   3311 C  CD    . GLU C 1 17  ? 112.383 127.476 115.800 1.00 89.87  ? 17  GLU B CD    1 
ATOM   3312 O  OE1   . GLU C 1 17  ? 112.057 128.483 115.136 1.00 85.67  ? 17  GLU B OE1   1 
ATOM   3313 O  OE2   . GLU C 1 17  ? 112.839 126.437 115.280 1.00 93.54  ? 17  GLU B OE2   1 
ATOM   3314 N  N     . ARG C 1 18  ? 114.749 128.775 121.113 1.00 65.01  ? 18  ARG B N     1 
ATOM   3315 C  CA    . ARG C 1 18  ? 115.945 128.274 121.765 1.00 57.67  ? 18  ARG B CA    1 
ATOM   3316 C  C     . ARG C 1 18  ? 115.587 127.300 122.883 1.00 54.54  ? 18  ARG B C     1 
ATOM   3317 O  O     . ARG C 1 18  ? 114.463 127.277 123.391 1.00 57.40  ? 18  ARG B O     1 
ATOM   3318 C  CB    . ARG C 1 18  ? 116.779 129.432 122.308 1.00 55.69  ? 18  ARG B CB    1 
ATOM   3319 C  CG    . ARG C 1 18  ? 117.791 129.955 121.310 1.00 64.63  ? 18  ARG B CG    1 
ATOM   3320 C  CD    . ARG C 1 18  ? 118.174 131.391 121.600 1.00 74.73  ? 18  ARG B CD    1 
ATOM   3321 N  NE    . ARG C 1 18  ? 119.090 131.911 120.592 1.00 81.29  ? 18  ARG B NE    1 
ATOM   3322 C  CZ    . ARG C 1 18  ? 119.340 133.199 120.402 1.00 83.43  ? 18  ARG B CZ    1 
ATOM   3323 N  NH1   . ARG C 1 18  ? 118.763 134.131 121.142 1.00 83.01  ? 18  ARG B NH1   1 
ATOM   3324 N  NH2   . ARG C 1 18  ? 120.190 133.560 119.446 1.00 79.44  ? 18  ARG B NH2   1 
ATOM   3325 N  N     . CYS C 1 19  ? 116.573 126.480 123.258 1.00 48.85  ? 19  CYS B N     1 
ATOM   3326 C  CA    . CYS C 1 19  ? 116.342 125.444 124.260 1.00 46.58  ? 19  CYS B CA    1 
ATOM   3327 C  C     . CYS C 1 19  ? 116.023 126.040 125.625 1.00 44.94  ? 19  CYS B C     1 
ATOM   3328 O  O     . CYS C 1 19  ? 115.118 125.564 126.318 1.00 48.12  ? 19  CYS B O     1 
ATOM   3329 C  CB    . CYS C 1 19  ? 117.560 124.527 124.351 1.00 44.91  ? 19  CYS B CB    1 
ATOM   3330 S  SG    . CYS C 1 19  ? 118.157 123.920 122.760 1.00 58.87  ? 19  CYS B SG    1 
ATOM   3331 N  N     . ILE C 1 20  ? 116.746 127.080 126.027 1.00 42.06  ? 20  ILE B N     1 
ATOM   3332 C  CA    . ILE C 1 20  ? 116.622 127.669 127.355 1.00 37.34  ? 20  ILE B CA    1 
ATOM   3333 C  C     . ILE C 1 20  ? 115.983 129.042 127.224 1.00 48.97  ? 20  ILE B C     1 
ATOM   3334 O  O     . ILE C 1 20  ? 116.463 129.887 126.460 1.00 61.98  ? 20  ILE B O     1 
ATOM   3335 C  CB    . ILE C 1 20  ? 117.987 127.773 128.052 1.00 38.90  ? 20  ILE B CB    1 
ATOM   3336 C  CG1   . ILE C 1 20  ? 118.663 126.403 128.103 1.00 44.55  ? 20  ILE B CG1   1 
ATOM   3337 C  CG2   . ILE C 1 20  ? 117.827 128.365 129.436 1.00 42.01  ? 20  ILE B CG2   1 
ATOM   3338 C  CD1   . ILE C 1 20  ? 118.265 125.572 129.289 1.00 44.30  ? 20  ILE B CD1   1 
ATOM   3339 N  N     . GLN C 1 21  ? 114.907 129.266 127.971 1.00 51.46  ? 21  GLN B N     1 
ATOM   3340 C  CA    . GLN C 1 21  ? 114.209 130.542 127.982 1.00 47.82  ? 21  GLN B CA    1 
ATOM   3341 C  C     . GLN C 1 21  ? 114.578 131.310 129.244 1.00 52.49  ? 21  GLN B C     1 
ATOM   3342 O  O     . GLN C 1 21  ? 114.520 130.763 130.351 1.00 57.98  ? 21  GLN B O     1 
ATOM   3343 C  CB    . GLN C 1 21  ? 112.696 130.333 127.913 1.00 46.45  ? 21  GLN B CB    1 
ATOM   3344 C  CG    . GLN C 1 21  ? 112.245 129.515 126.720 1.00 54.37  ? 21  GLN B CG    1 
ATOM   3345 C  CD    . GLN C 1 21  ? 112.684 130.118 125.404 1.00 59.14  ? 21  GLN B CD    1 
ATOM   3346 O  OE1   . GLN C 1 21  ? 113.695 129.717 124.832 1.00 57.48  ? 21  GLN B OE1   1 
ATOM   3347 N  NE2   . GLN C 1 21  ? 111.924 131.087 124.915 1.00 64.86  ? 21  GLN B NE2   1 
ATOM   3348 N  N     . ASP C 1 22  ? 114.963 132.571 129.073 1.00 53.23  ? 22  ASP B N     1 
ATOM   3349 C  CA    . ASP C 1 22  ? 115.312 133.441 130.190 1.00 54.15  ? 22  ASP B CA    1 
ATOM   3350 C  C     . ASP C 1 22  ? 114.033 134.102 130.688 1.00 51.37  ? 22  ASP B C     1 
ATOM   3351 O  O     . ASP C 1 22  ? 113.458 134.953 130.001 1.00 49.30  ? 22  ASP B O     1 
ATOM   3352 C  CB    . ASP C 1 22  ? 116.345 134.478 129.754 1.00 60.83  ? 22  ASP B CB    1 
ATOM   3353 C  CG    . ASP C 1 22  ? 116.628 135.521 130.821 1.00 67.21  ? 22  ASP B CG    1 
ATOM   3354 O  OD1   . ASP C 1 22  ? 117.175 136.588 130.472 1.00 68.79  ? 22  ASP B OD1   1 
ATOM   3355 O  OD2   . ASP C 1 22  ? 116.334 135.274 132.009 1.00 66.95  ? 22  ASP B OD2   1 
ATOM   3356 N  N     . ILE C 1 23  ? 113.585 133.711 131.879 1.00 54.39  ? 23  ILE B N     1 
ATOM   3357 C  CA    . ILE C 1 23  ? 112.367 134.267 132.456 1.00 57.38  ? 23  ILE B CA    1 
ATOM   3358 C  C     . ILE C 1 23  ? 112.683 134.919 133.794 1.00 60.39  ? 23  ILE B C     1 
ATOM   3359 O  O     . ILE C 1 23  ? 111.851 134.922 134.707 1.00 62.43  ? 23  ILE B O     1 
ATOM   3360 C  CB    . ILE C 1 23  ? 111.269 133.197 132.603 1.00 52.15  ? 23  ILE B CB    1 
ATOM   3361 C  CG1   . ILE C 1 23  ? 111.764 132.011 133.427 1.00 49.15  ? 23  ILE B CG1   1 
ATOM   3362 C  CG2   . ILE C 1 23  ? 110.795 132.730 131.239 1.00 55.28  ? 23  ILE B CG2   1 
ATOM   3363 C  CD1   . ILE C 1 23  ? 110.698 130.973 133.649 1.00 52.41  ? 23  ILE B CD1   1 
ATOM   3364 N  N     . ARG C 1 24  ? 113.893 135.467 133.922 1.00 56.93  ? 24  ARG B N     1 
ATOM   3365 C  CA    . ARG C 1 24  ? 114.244 136.199 135.134 1.00 59.06  ? 24  ARG B CA    1 
ATOM   3366 C  C     . ARG C 1 24  ? 113.343 137.414 135.323 1.00 61.73  ? 24  ARG B C     1 
ATOM   3367 O  O     . ARG C 1 24  ? 112.937 137.726 136.448 1.00 60.92  ? 24  ARG B O     1 
ATOM   3368 C  CB    . ARG C 1 24  ? 115.711 136.625 135.089 1.00 59.27  ? 24  ARG B CB    1 
ATOM   3369 C  CG    . ARG C 1 24  ? 116.448 136.493 136.415 1.00 71.06  ? 24  ARG B CG    1 
ATOM   3370 C  CD    . ARG C 1 24  ? 116.018 137.558 137.422 1.00 68.21  ? 24  ARG B CD    1 
ATOM   3371 N  NE    . ARG C 1 24  ? 116.979 137.700 138.510 1.00 62.73  ? 24  ARG B NE    1 
ATOM   3372 C  CZ    . ARG C 1 24  ? 117.093 138.775 139.278 1.00 50.99  ? 24  ARG B CZ    1 
ATOM   3373 N  NH1   . ARG C 1 24  ? 116.301 139.822 139.121 1.00 45.04  ? 24  ARG B NH1   1 
ATOM   3374 N  NH2   . ARG C 1 24  ? 118.027 138.799 140.224 1.00 42.99  ? 24  ARG B NH2   1 
ATOM   3375 N  N     . ASN C 1 25  ? 113.018 138.109 134.235 1.00 60.25  ? 25  ASN B N     1 
ATOM   3376 C  CA    . ASN C 1 25  ? 112.186 139.302 134.303 1.00 56.77  ? 25  ASN B CA    1 
ATOM   3377 C  C     . ASN C 1 25  ? 110.694 139.002 134.251 1.00 59.52  ? 25  ASN B C     1 
ATOM   3378 O  O     . ASN C 1 25  ? 109.890 139.917 134.454 1.00 67.05  ? 25  ASN B O     1 
ATOM   3379 C  CB    . ASN C 1 25  ? 112.546 140.264 133.167 1.00 56.61  ? 25  ASN B CB    1 
ATOM   3380 C  CG    . ASN C 1 25  ? 113.694 141.185 133.524 1.00 64.55  ? 25  ASN B CG    1 
ATOM   3381 O  OD1   . ASN C 1 25  ? 113.663 141.866 134.548 1.00 67.29  ? 25  ASN B OD1   1 
ATOM   3382 N  ND2   . ASN C 1 25  ? 114.717 141.208 132.680 1.00 70.76  ? 25  ASN B ND2   1 
ATOM   3383 N  N     . ALA C 1 26  ? 110.303 137.759 133.980 1.00 54.72  ? 26  ALA B N     1 
ATOM   3384 C  CA    . ALA C 1 26  ? 108.898 137.356 133.938 1.00 53.66  ? 26  ALA B CA    1 
ATOM   3385 C  C     . ALA C 1 26  ? 108.720 136.088 134.762 1.00 56.44  ? 26  ALA B C     1 
ATOM   3386 O  O     . ALA C 1 26  ? 108.475 135.006 134.217 1.00 64.15  ? 26  ALA B O     1 
ATOM   3387 C  CB    . ALA C 1 26  ? 108.430 137.147 132.498 1.00 53.56  ? 26  ALA B CB    1 
ATOM   3388 N  N     . PRO C 1 27  ? 108.831 136.189 136.085 1.00 57.83  ? 27  PRO B N     1 
ATOM   3389 C  CA    . PRO C 1 27  ? 108.804 134.984 136.920 1.00 61.34  ? 27  PRO B CA    1 
ATOM   3390 C  C     . PRO C 1 27  ? 107.447 134.302 136.896 1.00 67.06  ? 27  PRO B C     1 
ATOM   3391 O  O     . PRO C 1 27  ? 106.412 134.925 136.647 1.00 68.36  ? 27  PRO B O     1 
ATOM   3392 C  CB    . PRO C 1 27  ? 109.128 135.512 138.325 1.00 55.26  ? 27  PRO B CB    1 
ATOM   3393 C  CG    . PRO C 1 27  ? 109.593 136.924 138.136 1.00 54.23  ? 27  PRO B CG    1 
ATOM   3394 C  CD    . PRO C 1 27  ? 108.937 137.413 136.892 1.00 59.09  ? 27  PRO B CD    1 
ATOM   3395 N  N     . VAL C 1 28  ? 107.469 132.995 137.152 1.00 71.42  ? 28  VAL B N     1 
ATOM   3396 C  CA    . VAL C 1 28  ? 106.245 132.224 137.336 1.00 69.88  ? 28  VAL B CA    1 
ATOM   3397 C  C     . VAL C 1 28  ? 105.694 132.609 138.704 1.00 76.66  ? 28  VAL B C     1 
ATOM   3398 O  O     . VAL C 1 28  ? 106.406 133.210 139.516 1.00 82.06  ? 28  VAL B O     1 
ATOM   3399 C  CB    . VAL C 1 28  ? 106.515 130.713 137.212 1.00 69.38  ? 28  VAL B CB    1 
ATOM   3400 C  CG1   . VAL C 1 28  ? 105.215 129.922 137.158 1.00 69.97  ? 28  VAL B CG1   1 
ATOM   3401 C  CG2   . VAL C 1 28  ? 107.355 130.433 135.978 1.00 72.71  ? 28  VAL B CG2   1 
ATOM   3402 N  N     . ARG C 1 29  ? 104.427 132.281 138.968 1.00 76.06  ? 29  ARG B N     1 
ATOM   3403 C  CA    . ARG C 1 29  ? 103.741 132.825 140.136 1.00 84.28  ? 29  ARG B CA    1 
ATOM   3404 C  C     . ARG C 1 29  ? 104.429 132.414 141.434 1.00 85.80  ? 29  ARG B C     1 
ATOM   3405 O  O     . ARG C 1 29  ? 104.927 133.262 142.183 1.00 90.87  ? 29  ARG B O     1 
ATOM   3406 C  CB    . ARG C 1 29  ? 102.276 132.384 140.132 1.00 87.26  ? 29  ARG B CB    1 
ATOM   3407 C  CG    . ARG C 1 29  ? 101.340 133.258 140.968 1.00 87.99  ? 29  ARG B CG    1 
ATOM   3408 C  CD    . ARG C 1 29  ? 101.840 134.694 141.116 1.00 89.74  ? 29  ARG B CD    1 
ATOM   3409 N  NE    . ARG C 1 29  ? 101.923 135.399 139.841 1.00 93.18  ? 29  ARG B NE    1 
ATOM   3410 C  CZ    . ARG C 1 29  ? 102.820 136.335 139.560 1.00 95.59  ? 29  ARG B CZ    1 
ATOM   3411 N  NH1   . ARG C 1 29  ? 103.729 136.708 140.445 1.00 94.90  ? 29  ARG B NH1   1 
ATOM   3412 N  NH2   . ARG C 1 29  ? 102.806 136.908 138.360 1.00 93.82  ? 29  ARG B NH2   1 
ATOM   3413 N  N     . ASN C 1 30  ? 104.475 131.116 141.715 1.00 76.98  ? 30  ASN B N     1 
ATOM   3414 C  CA    . ASN C 1 30  ? 104.984 130.610 142.984 1.00 75.29  ? 30  ASN B CA    1 
ATOM   3415 C  C     . ASN C 1 30  ? 106.250 129.785 142.790 1.00 76.24  ? 30  ASN B C     1 
ATOM   3416 O  O     . ASN C 1 30  ? 106.448 128.757 143.439 1.00 79.15  ? 30  ASN B O     1 
ATOM   3417 C  CB    . ASN C 1 30  ? 103.917 129.791 143.705 1.00 83.32  ? 30  ASN B CB    1 
ATOM   3418 C  CG    . ASN C 1 30  ? 102.947 130.656 144.485 1.00 92.89  ? 30  ASN B CG    1 
ATOM   3419 O  OD1   . ASN C 1 30  ? 103.353 131.540 145.237 1.00 96.57  ? 30  ASN B OD1   1 
ATOM   3420 N  ND2   . ASN C 1 30  ? 101.656 130.402 144.311 1.00 100.98 ? 30  ASN B ND2   1 
ATOM   3421 N  N     . ARG C 1 31  ? 107.129 130.230 141.895 1.00 74.24  ? 31  ARG B N     1 
ATOM   3422 C  CA    . ARG C 1 31  ? 108.381 129.536 141.633 1.00 65.82  ? 31  ARG B CA    1 
ATOM   3423 C  C     . ARG C 1 31  ? 109.491 130.557 141.440 1.00 66.44  ? 31  ARG B C     1 
ATOM   3424 O  O     . ARG C 1 31  ? 109.242 131.743 141.213 1.00 71.60  ? 31  ARG B O     1 
ATOM   3425 C  CB    . ARG C 1 31  ? 108.283 128.627 140.403 1.00 58.58  ? 31  ARG B CB    1 
ATOM   3426 C  CG    . ARG C 1 31  ? 107.317 127.473 140.564 1.00 56.95  ? 31  ARG B CG    1 
ATOM   3427 C  CD    . ARG C 1 31  ? 107.355 126.545 139.371 1.00 48.86  ? 31  ARG B CD    1 
ATOM   3428 N  NE    . ARG C 1 31  ? 106.122 125.777 139.261 1.00 39.05  ? 31  ARG B NE    1 
ATOM   3429 C  CZ    . ARG C 1 31  ? 105.556 125.435 138.114 1.00 48.36  ? 31  ARG B CZ    1 
ATOM   3430 N  NH1   . ARG C 1 31  ? 106.104 125.752 136.953 1.00 57.42  ? 31  ARG B NH1   1 
ATOM   3431 N  NH2   . ARG C 1 31  ? 104.411 124.760 138.131 1.00 54.62  ? 31  ARG B NH2   1 
ATOM   3432 N  N     . SER C 1 32  ? 110.728 130.077 141.535 1.00 62.19  ? 32  SER B N     1 
ATOM   3433 C  CA    . SER C 1 32  ? 111.914 130.904 141.350 1.00 60.23  ? 32  SER B CA    1 
ATOM   3434 C  C     . SER C 1 32  ? 112.774 130.388 140.202 1.00 56.80  ? 32  SER B C     1 
ATOM   3435 O  O     . SER C 1 32  ? 114.002 130.470 140.251 1.00 54.31  ? 32  SER B O     1 
ATOM   3436 C  CB    . SER C 1 32  ? 112.728 130.973 142.641 1.00 56.31  ? 32  SER B CB    1 
ATOM   3437 O  OG    . SER C 1 32  ? 113.274 129.706 142.962 1.00 54.17  ? 32  SER B OG    1 
ATOM   3438 N  N     . THR C 1 33  ? 112.138 129.852 139.165 1.00 53.10  ? 33  THR B N     1 
ATOM   3439 C  CA    . THR C 1 33  ? 112.854 129.309 138.014 1.00 45.36  ? 33  THR B CA    1 
ATOM   3440 C  C     . THR C 1 33  ? 113.423 130.463 137.203 1.00 48.62  ? 33  THR B C     1 
ATOM   3441 O  O     . THR C 1 33  ? 112.712 131.103 136.427 1.00 60.80  ? 33  THR B O     1 
ATOM   3442 C  CB    . THR C 1 33  ? 111.924 128.452 137.164 1.00 44.45  ? 33  THR B CB    1 
ATOM   3443 O  OG1   . THR C 1 33  ? 111.151 129.296 136.307 1.00 57.52  ? 33  THR B OG1   1 
ATOM   3444 C  CG2   . THR C 1 33  ? 110.982 127.657 138.042 1.00 45.35  ? 33  THR B CG2   1 
ATOM   3445 N  N     . GLN C 1 34  ? 114.715 130.741 137.385 1.00 44.16  ? 34  GLN B N     1 
ATOM   3446 C  CA    . GLN C 1 34  ? 115.347 131.817 136.630 1.00 50.26  ? 34  GLN B CA    1 
ATOM   3447 C  C     . GLN C 1 34  ? 115.419 131.480 135.146 1.00 55.73  ? 34  GLN B C     1 
ATOM   3448 O  O     . GLN C 1 34  ? 115.002 132.277 134.298 1.00 61.20  ? 34  GLN B O     1 
ATOM   3449 C  CB    . GLN C 1 34  ? 116.740 132.100 137.188 1.00 47.51  ? 34  GLN B CB    1 
ATOM   3450 C  CG    . GLN C 1 34  ? 116.730 132.683 138.585 1.00 46.26  ? 34  GLN B CG    1 
ATOM   3451 C  CD    . GLN C 1 34  ? 118.024 133.382 138.931 1.00 52.48  ? 34  GLN B CD    1 
ATOM   3452 O  OE1   . GLN C 1 34  ? 118.857 133.636 138.064 1.00 51.98  ? 34  GLN B OE1   1 
ATOM   3453 N  NE2   . GLN C 1 34  ? 118.199 133.701 140.206 1.00 62.64  ? 34  GLN B NE2   1 
ATOM   3454 N  N     . PHE C 1 35  ? 115.932 130.299 134.813 1.00 50.79  ? 35  PHE B N     1 
ATOM   3455 C  CA    . PHE C 1 35  ? 116.024 129.836 133.435 1.00 45.16  ? 35  PHE B CA    1 
ATOM   3456 C  C     . PHE C 1 35  ? 115.171 128.587 133.286 1.00 46.51  ? 35  PHE B C     1 
ATOM   3457 O  O     . PHE C 1 35  ? 115.267 127.664 134.102 1.00 49.55  ? 35  PHE B O     1 
ATOM   3458 C  CB    . PHE C 1 35  ? 117.471 129.539 133.040 1.00 40.31  ? 35  PHE B CB    1 
ATOM   3459 C  CG    . PHE C 1 35  ? 118.391 130.712 133.186 1.00 42.59  ? 35  PHE B CG    1 
ATOM   3460 C  CD1   . PHE C 1 35  ? 119.036 130.955 134.383 1.00 48.88  ? 35  PHE B CD1   1 
ATOM   3461 C  CD2   . PHE C 1 35  ? 118.611 131.572 132.129 1.00 46.60  ? 35  PHE B CD2   1 
ATOM   3462 C  CE1   . PHE C 1 35  ? 119.884 132.032 134.524 1.00 49.66  ? 35  PHE B CE1   1 
ATOM   3463 C  CE2   . PHE C 1 35  ? 119.458 132.652 132.266 1.00 54.19  ? 35  PHE B CE2   1 
ATOM   3464 C  CZ    . PHE C 1 35  ? 120.095 132.882 133.465 1.00 53.22  ? 35  PHE B CZ    1 
ATOM   3465 N  N     . GLN C 1 36  ? 114.344 128.555 132.247 1.00 45.03  ? 36  GLN B N     1 
ATOM   3466 C  CA    . GLN C 1 36  ? 113.391 127.474 132.035 1.00 45.02  ? 36  GLN B CA    1 
ATOM   3467 C  C     . GLN C 1 36  ? 113.838 126.637 130.845 1.00 48.81  ? 36  GLN B C     1 
ATOM   3468 O  O     . GLN C 1 36  ? 114.017 127.163 129.743 1.00 59.53  ? 36  GLN B O     1 
ATOM   3469 C  CB    . GLN C 1 36  ? 111.987 128.037 131.812 1.00 48.63  ? 36  GLN B CB    1 
ATOM   3470 C  CG    . GLN C 1 36  ? 111.131 127.263 130.828 1.00 50.86  ? 36  GLN B CG    1 
ATOM   3471 C  CD    . GLN C 1 36  ? 109.668 127.637 130.922 1.00 64.39  ? 36  GLN B CD    1 
ATOM   3472 O  OE1   . GLN C 1 36  ? 109.190 128.053 131.975 1.00 67.06  ? 36  GLN B OE1   1 
ATOM   3473 N  NE2   . GLN C 1 36  ? 108.948 127.496 129.816 1.00 71.50  ? 36  GLN B NE2   1 
ATOM   3474 N  N     . LEU C 1 37  ? 114.044 125.344 131.074 1.00 41.60  ? 37  LEU B N     1 
ATOM   3475 C  CA    . LEU C 1 37  ? 114.238 124.418 129.968 1.00 39.06  ? 37  LEU B CA    1 
ATOM   3476 C  C     . LEU C 1 37  ? 112.939 124.304 129.183 1.00 43.60  ? 37  LEU B C     1 
ATOM   3477 O  O     . LEU C 1 37  ? 111.856 124.249 129.770 1.00 55.57  ? 37  LEU B O     1 
ATOM   3478 C  CB    . LEU C 1 37  ? 114.666 123.045 130.482 1.00 40.16  ? 37  LEU B CB    1 
ATOM   3479 C  CG    . LEU C 1 37  ? 116.160 122.754 130.626 1.00 32.55  ? 37  LEU B CG    1 
ATOM   3480 C  CD1   . LEU C 1 37  ? 116.733 123.474 131.821 1.00 32.12  ? 37  LEU B CD1   1 
ATOM   3481 C  CD2   . LEU C 1 37  ? 116.400 121.263 130.742 1.00 31.39  ? 37  LEU B CD2   1 
ATOM   3482 N  N     . ALA C 1 38  ? 113.037 124.277 127.861 1.00 36.46  ? 38  ALA B N     1 
ATOM   3483 C  CA    . ALA C 1 38  ? 111.865 124.165 126.997 1.00 48.69  ? 38  ALA B CA    1 
ATOM   3484 C  C     . ALA C 1 38  ? 111.928 122.810 126.300 1.00 53.22  ? 38  ALA B C     1 
ATOM   3485 O  O     . ALA C 1 38  ? 112.490 122.687 125.212 1.00 55.52  ? 38  ALA B O     1 
ATOM   3486 C  CB    . ALA C 1 38  ? 111.813 125.309 125.995 1.00 54.65  ? 38  ALA B CB    1 
ATOM   3487 N  N     . GLN C 1 39  ? 111.287 121.807 126.908 1.00 52.93  ? 39  GLN B N     1 
ATOM   3488 C  CA    . GLN C 1 39  ? 111.474 120.427 126.470 1.00 49.08  ? 39  GLN B CA    1 
ATOM   3489 C  C     . GLN C 1 39  ? 111.075 120.229 125.011 1.00 52.88  ? 39  GLN B C     1 
ATOM   3490 O  O     . GLN C 1 39  ? 111.705 119.433 124.304 1.00 58.08  ? 39  GLN B O     1 
ATOM   3491 C  CB    . GLN C 1 39  ? 110.696 119.482 127.387 1.00 44.67  ? 39  GLN B CB    1 
ATOM   3492 C  CG    . GLN C 1 39  ? 109.336 119.063 126.874 1.00 49.55  ? 39  GLN B CG    1 
ATOM   3493 C  CD    . GLN C 1 39  ? 108.517 118.345 127.919 1.00 59.69  ? 39  GLN B CD    1 
ATOM   3494 O  OE1   . GLN C 1 39  ? 108.818 118.407 129.109 1.00 65.50  ? 39  GLN B OE1   1 
ATOM   3495 N  NE2   . GLN C 1 39  ? 107.473 117.656 127.482 1.00 58.33  ? 39  GLN B NE2   1 
ATOM   3496 N  N     . GLN C 1 40  ? 110.055 120.947 124.535 1.00 53.19  ? 40  GLN B N     1 
ATOM   3497 C  CA    . GLN C 1 40  ? 109.685 120.844 123.128 1.00 55.52  ? 40  GLN B CA    1 
ATOM   3498 C  C     . GLN C 1 40  ? 110.790 121.381 122.226 1.00 54.74  ? 40  GLN B C     1 
ATOM   3499 O  O     . GLN C 1 40  ? 111.105 120.781 121.190 1.00 53.79  ? 40  GLN B O     1 
ATOM   3500 C  CB    . GLN C 1 40  ? 108.371 121.582 122.874 1.00 59.26  ? 40  GLN B CB    1 
ATOM   3501 C  CG    . GLN C 1 40  ? 107.323 121.362 123.950 1.00 66.30  ? 40  GLN B CG    1 
ATOM   3502 C  CD    . GLN C 1 40  ? 106.377 120.226 123.621 1.00 75.27  ? 40  GLN B CD    1 
ATOM   3503 O  OE1   . GLN C 1 40  ? 105.596 120.306 122.673 1.00 83.02  ? 40  GLN B OE1   1 
ATOM   3504 N  NE2   . GLN C 1 40  ? 106.445 119.156 124.402 1.00 77.84  ? 40  GLN B NE2   1 
ATOM   3505 N  N     . ASN C 1 41  ? 111.410 122.495 122.617 1.00 47.76  ? 41  ASN B N     1 
ATOM   3506 C  CA    . ASN C 1 41  ? 112.442 123.100 121.783 1.00 44.93  ? 41  ASN B CA    1 
ATOM   3507 C  C     . ASN C 1 41  ? 113.703 122.246 121.744 1.00 52.32  ? 41  ASN B C     1 
ATOM   3508 O  O     . ASN C 1 41  ? 114.311 122.084 120.682 1.00 59.63  ? 41  ASN B O     1 
ATOM   3509 C  CB    . ASN C 1 41  ? 112.756 124.509 122.277 1.00 48.11  ? 41  ASN B CB    1 
ATOM   3510 C  CG    . ASN C 1 41  ? 111.609 125.470 122.047 1.00 59.84  ? 41  ASN B CG    1 
ATOM   3511 O  OD1   . ASN C 1 41  ? 110.879 125.356 121.066 1.00 64.87  ? 41  ASN B OD1   1 
ATOM   3512 N  ND2   . ASN C 1 41  ? 111.446 126.427 122.951 1.00 66.72  ? 41  ASN B ND2   1 
ATOM   3513 N  N     . MET C 1 42  ? 114.110 121.678 122.880 1.00 49.74  ? 42  MET B N     1 
ATOM   3514 C  CA    . MET C 1 42  ? 115.292 120.820 122.870 1.00 42.19  ? 42  MET B CA    1 
ATOM   3515 C  C     . MET C 1 42  ? 115.011 119.499 122.173 1.00 43.85  ? 42  MET B C     1 
ATOM   3516 O  O     . MET C 1 42  ? 115.904 118.924 121.545 1.00 49.22  ? 42  MET B O     1 
ATOM   3517 C  CB    . MET C 1 42  ? 115.791 120.568 124.287 1.00 42.49  ? 42  MET B CB    1 
ATOM   3518 C  CG    . MET C 1 42  ? 115.250 121.521 125.304 1.00 53.82  ? 42  MET B CG    1 
ATOM   3519 S  SD    . MET C 1 42  ? 116.141 121.385 126.845 1.00 58.59  ? 42  MET B SD    1 
ATOM   3520 C  CE    . MET C 1 42  ? 115.624 119.752 127.301 1.00 37.91  ? 42  MET B CE    1 
ATOM   3521 N  N     . LEU C 1 43  ? 113.785 118.986 122.289 1.00 45.72  ? 43  LEU B N     1 
ATOM   3522 C  CA    . LEU C 1 43  ? 113.431 117.785 121.544 1.00 44.15  ? 43  LEU B CA    1 
ATOM   3523 C  C     . LEU C 1 43  ? 113.477 118.036 120.043 1.00 48.76  ? 43  LEU B C     1 
ATOM   3524 O  O     . LEU C 1 43  ? 113.927 117.177 119.277 1.00 50.08  ? 43  LEU B O     1 
ATOM   3525 C  CB    . LEU C 1 43  ? 112.049 117.295 121.963 1.00 40.43  ? 43  LEU B CB    1 
ATOM   3526 C  CG    . LEU C 1 43  ? 112.055 116.062 122.857 1.00 37.55  ? 43  LEU B CG    1 
ATOM   3527 C  CD1   . LEU C 1 43  ? 110.685 115.858 123.453 1.00 45.83  ? 43  LEU B CD1   1 
ATOM   3528 C  CD2   . LEU C 1 43  ? 112.492 114.845 122.074 1.00 43.47  ? 43  LEU B CD2   1 
ATOM   3529 N  N     . ALA C 1 44  ? 113.007 119.205 119.600 1.00 49.08  ? 44  ALA B N     1 
ATOM   3530 C  CA    . ALA C 1 44  ? 113.081 119.533 118.182 1.00 49.13  ? 44  ALA B CA    1 
ATOM   3531 C  C     . ALA C 1 44  ? 114.490 119.906 117.743 1.00 48.07  ? 44  ALA B C     1 
ATOM   3532 O  O     . ALA C 1 44  ? 114.790 119.837 116.547 1.00 52.54  ? 44  ALA B O     1 
ATOM   3533 C  CB    . ALA C 1 44  ? 112.118 120.672 117.854 1.00 54.56  ? 44  ALA B CB    1 
ATOM   3534 N  N     . TYR C 1 45  ? 115.356 120.305 118.675 1.00 43.35  ? 45  TYR B N     1 
ATOM   3535 C  CA    . TYR C 1 45  ? 116.718 120.686 118.321 1.00 46.47  ? 45  TYR B CA    1 
ATOM   3536 C  C     . TYR C 1 45  ? 117.636 119.471 118.240 1.00 53.39  ? 45  TYR B C     1 
ATOM   3537 O  O     . TYR C 1 45  ? 118.279 119.238 117.211 1.00 61.69  ? 45  TYR B O     1 
ATOM   3538 C  CB    . TYR C 1 45  ? 117.249 121.698 119.336 1.00 47.95  ? 45  TYR B CB    1 
ATOM   3539 C  CG    . TYR C 1 45  ? 118.710 122.047 119.177 1.00 53.26  ? 45  TYR B CG    1 
ATOM   3540 C  CD1   . TYR C 1 45  ? 119.133 122.907 118.177 1.00 53.84  ? 45  TYR B CD1   1 
ATOM   3541 C  CD2   . TYR C 1 45  ? 119.664 121.528 120.038 1.00 53.50  ? 45  TYR B CD2   1 
ATOM   3542 C  CE1   . TYR C 1 45  ? 120.463 123.230 118.035 1.00 52.02  ? 45  TYR B CE1   1 
ATOM   3543 C  CE2   . TYR C 1 45  ? 120.994 121.847 119.901 1.00 54.75  ? 45  TYR B CE2   1 
ATOM   3544 C  CZ    . TYR C 1 45  ? 121.388 122.697 118.900 1.00 57.18  ? 45  TYR B CZ    1 
ATOM   3545 O  OH    . TYR C 1 45  ? 122.716 123.017 118.762 1.00 71.49  ? 45  TYR B OH    1 
ATOM   3546 N  N     . THR C 1 46  ? 117.710 118.687 119.317 1.00 50.08  ? 46  THR B N     1 
ATOM   3547 C  CA    . THR C 1 46  ? 118.576 117.513 119.327 1.00 48.16  ? 46  THR B CA    1 
ATOM   3548 C  C     . THR C 1 46  ? 118.049 116.440 118.383 1.00 52.76  ? 46  THR B C     1 
ATOM   3549 O  O     . THR C 1 46  ? 118.717 116.066 117.413 1.00 63.12  ? 46  THR B O     1 
ATOM   3550 C  CB    . THR C 1 46  ? 118.699 116.966 120.750 1.00 45.70  ? 46  THR B CB    1 
ATOM   3551 O  OG1   . THR C 1 46  ? 119.521 117.841 121.530 1.00 49.73  ? 46  THR B OG1   1 
ATOM   3552 C  CG2   . THR C 1 46  ? 119.325 115.586 120.733 1.00 44.42  ? 46  THR B CG2   1 
ATOM   3553 N  N     . PHE C 1 47  ? 116.845 115.941 118.643 1.00 48.15  ? 47  PHE B N     1 
ATOM   3554 C  CA    . PHE C 1 47  ? 116.223 114.933 117.785 1.00 44.98  ? 47  PHE B CA    1 
ATOM   3555 C  C     . PHE C 1 47  ? 115.425 115.579 116.658 1.00 53.44  ? 47  PHE B C     1 
ATOM   3556 O  O     . PHE C 1 47  ? 114.252 115.279 116.450 1.00 58.37  ? 47  PHE B O     1 
ATOM   3557 C  CB    . PHE C 1 47  ? 115.344 114.009 118.618 1.00 41.32  ? 47  PHE B CB    1 
ATOM   3558 C  CG    . PHE C 1 47  ? 116.075 113.316 119.730 1.00 47.18  ? 47  PHE B CG    1 
ATOM   3559 C  CD1   . PHE C 1 47  ? 116.979 112.306 119.457 1.00 55.78  ? 47  PHE B CD1   1 
ATOM   3560 C  CD2   . PHE C 1 47  ? 115.853 113.669 121.049 1.00 43.67  ? 47  PHE B CD2   1 
ATOM   3561 C  CE1   . PHE C 1 47  ? 117.650 111.667 120.477 1.00 50.85  ? 47  PHE B CE1   1 
ATOM   3562 C  CE2   . PHE C 1 47  ? 116.522 113.031 122.072 1.00 37.23  ? 47  PHE B CE2   1 
ATOM   3563 C  CZ    . PHE C 1 47  ? 117.421 112.030 121.786 1.00 40.76  ? 47  PHE B CZ    1 
ATOM   3564 N  N     . GLY C 1 48  ? 116.063 116.477 115.916 1.00 51.97  ? 48  GLY B N     1 
ATOM   3565 C  CA    . GLY C 1 48  ? 115.393 117.151 114.823 1.00 52.66  ? 48  GLY B CA    1 
ATOM   3566 C  C     . GLY C 1 48  ? 115.436 116.352 113.540 1.00 57.28  ? 48  GLY B C     1 
ATOM   3567 O  O     . GLY C 1 48  ? 114.430 116.227 112.839 1.00 57.57  ? 48  GLY B O     1 
ATOM   3568 N  N     . GLU C 1 49  ? 116.606 115.803 113.227 1.00 63.57  ? 49  GLU B N     1 
ATOM   3569 C  CA    . GLU C 1 49  ? 116.783 114.984 112.040 1.00 65.22  ? 49  GLU B CA    1 
ATOM   3570 C  C     . GLU C 1 49  ? 117.215 113.562 112.364 1.00 66.98  ? 49  GLU B C     1 
ATOM   3571 O  O     . GLU C 1 49  ? 117.479 112.787 111.440 1.00 71.20  ? 49  GLU B O     1 
ATOM   3572 C  CB    . GLU C 1 49  ? 117.813 115.625 111.098 1.00 72.69  ? 49  GLU B CB    1 
ATOM   3573 C  CG    . GLU C 1 49  ? 119.056 116.133 111.809 1.00 81.75  ? 49  GLU B CG    1 
ATOM   3574 C  CD    . GLU C 1 49  ? 119.747 117.250 111.056 1.00 88.67  ? 49  GLU B CD    1 
ATOM   3575 O  OE1   . GLU C 1 49  ? 119.220 117.682 110.010 1.00 86.63  ? 49  GLU B OE1   1 
ATOM   3576 O  OE2   . GLU C 1 49  ? 120.821 117.697 111.510 1.00 88.02  ? 49  GLU B OE2   1 
ATOM   3577 N  N     . VAL C 1 50  ? 117.298 113.201 113.641 1.00 59.66  ? 50  VAL B N     1 
ATOM   3578 C  CA    . VAL C 1 50  ? 117.734 111.878 114.066 1.00 54.48  ? 50  VAL B CA    1 
ATOM   3579 C  C     . VAL C 1 50  ? 116.718 111.326 115.053 1.00 56.45  ? 50  VAL B C     1 
ATOM   3580 O  O     . VAL C 1 50  ? 116.407 111.974 116.057 1.00 60.87  ? 50  VAL B O     1 
ATOM   3581 C  CB    . VAL C 1 50  ? 119.137 111.920 114.700 1.00 50.55  ? 50  VAL B CB    1 
ATOM   3582 C  CG1   . VAL C 1 50  ? 119.332 113.214 115.463 1.00 53.79  ? 50  VAL B CG1   1 
ATOM   3583 C  CG2   . VAL C 1 50  ? 119.332 110.732 115.621 1.00 53.02  ? 50  VAL B CG2   1 
ATOM   3584 N  N     . ILE C 1 51  ? 116.203 110.141 114.765 1.00 55.27  ? 51  ILE B N     1 
ATOM   3585 C  CA    . ILE C 1 51  ? 115.348 109.392 115.682 1.00 57.33  ? 51  ILE B CA    1 
ATOM   3586 C  C     . ILE C 1 51  ? 116.112 108.150 116.119 1.00 65.77  ? 51  ILE B C     1 
ATOM   3587 O  O     . ILE C 1 51  ? 116.613 107.414 115.261 1.00 71.75  ? 51  ILE B O     1 
ATOM   3588 C  CB    . ILE C 1 51  ? 114.005 109.008 115.036 1.00 51.24  ? 51  ILE B CB    1 
ATOM   3589 C  CG1   . ILE C 1 51  ? 112.992 110.131 115.231 1.00 54.68  ? 51  ILE B CG1   1 
ATOM   3590 C  CG2   . ILE C 1 51  ? 113.465 107.737 115.653 1.00 53.06  ? 51  ILE B CG2   1 
ATOM   3591 C  CD1   . ILE C 1 51  ? 112.652 110.382 116.677 1.00 53.28  ? 51  ILE B CD1   1 
ATOM   3592 N  N     . PRO C 1 52  ? 116.248 107.894 117.419 1.00 57.37  ? 52  PRO B N     1 
ATOM   3593 C  CA    . PRO C 1 52  ? 117.008 106.723 117.862 1.00 60.10  ? 52  PRO B CA    1 
ATOM   3594 C  C     . PRO C 1 52  ? 116.381 105.434 117.357 1.00 65.98  ? 52  PRO B C     1 
ATOM   3595 O  O     . PRO C 1 52  ? 115.162 105.323 117.216 1.00 68.59  ? 52  PRO B O     1 
ATOM   3596 C  CB    . PRO C 1 52  ? 116.945 106.815 119.391 1.00 59.96  ? 52  PRO B CB    1 
ATOM   3597 C  CG    . PRO C 1 52  ? 116.574 108.232 119.678 1.00 54.06  ? 52  PRO B CG    1 
ATOM   3598 C  CD    . PRO C 1 52  ? 115.701 108.657 118.550 1.00 52.22  ? 52  PRO B CD    1 
ATOM   3599 N  N     . GLY C 1 53  ? 117.237 104.459 117.059 1.00 67.29  ? 53  GLY B N     1 
ATOM   3600 C  CA    . GLY C 1 53  ? 116.784 103.189 116.539 1.00 71.26  ? 53  GLY B CA    1 
ATOM   3601 C  C     . GLY C 1 53  ? 116.474 103.181 115.062 1.00 74.28  ? 53  GLY B C     1 
ATOM   3602 O  O     . GLY C 1 53  ? 116.261 102.101 114.496 1.00 80.72  ? 53  GLY B O     1 
ATOM   3603 N  N     . PHE C 1 54  ? 116.439 104.347 114.415 1.00 66.33  ? 54  PHE B N     1 
ATOM   3604 C  CA    . PHE C 1 54  ? 116.221 104.445 112.977 1.00 68.44  ? 54  PHE B CA    1 
ATOM   3605 C  C     . PHE C 1 54  ? 117.139 105.493 112.363 1.00 71.27  ? 54  PHE B C     1 
ATOM   3606 O  O     . PHE C 1 54  ? 116.768 106.162 111.392 1.00 76.23  ? 54  PHE B O     1 
ATOM   3607 C  CB    . PHE C 1 54  ? 114.759 104.755 112.661 1.00 63.51  ? 54  PHE B CB    1 
ATOM   3608 C  CG    . PHE C 1 54  ? 113.815 103.658 113.055 1.00 68.09  ? 54  PHE B CG    1 
ATOM   3609 C  CD1   . PHE C 1 54  ? 113.489 102.654 112.163 1.00 75.61  ? 54  PHE B CD1   1 
ATOM   3610 C  CD2   . PHE C 1 54  ? 113.261 103.625 114.322 1.00 68.81  ? 54  PHE B CD2   1 
ATOM   3611 C  CE1   . PHE C 1 54  ? 112.626 101.640 112.526 1.00 73.80  ? 54  PHE B CE1   1 
ATOM   3612 C  CE2   . PHE C 1 54  ? 112.399 102.613 114.688 1.00 69.69  ? 54  PHE B CE2   1 
ATOM   3613 C  CZ    . PHE C 1 54  ? 112.080 101.621 113.790 1.00 68.59  ? 54  PHE B CZ    1 
ATOM   3614 N  N     . ALA C 1 55  ? 118.335 105.646 112.925 1.00 66.62  ? 55  ALA B N     1 
ATOM   3615 C  CA    . ALA C 1 55  ? 119.332 106.590 112.443 1.00 64.76  ? 55  ALA B CA    1 
ATOM   3616 C  C     . ALA C 1 55  ? 120.638 105.854 112.178 1.00 70.15  ? 55  ALA B C     1 
ATOM   3617 O  O     . ALA C 1 55  ? 120.651 104.620 112.117 1.00 68.52  ? 55  ALA B O     1 
ATOM   3618 C  CB    . ALA C 1 55  ? 119.543 107.720 113.450 1.00 61.57  ? 55  ALA B CB    1 
ATOM   3619 N  N     . SER C 1 56  ? 121.727 106.600 111.991 1.00 70.07  ? 56  SER B N     1 
ATOM   3620 C  CA    . SER C 1 56  ? 123.033 105.994 111.761 1.00 71.91  ? 56  SER B CA    1 
ATOM   3621 C  C     . SER C 1 56  ? 123.346 104.958 112.834 1.00 68.74  ? 56  SER B C     1 
ATOM   3622 O  O     . SER C 1 56  ? 122.886 105.054 113.975 1.00 66.93  ? 56  SER B O     1 
ATOM   3623 C  CB    . SER C 1 56  ? 124.118 107.071 111.737 1.00 72.11  ? 56  SER B CB    1 
ATOM   3624 O  OG    . SER C 1 56  ? 123.806 108.125 112.631 1.00 71.46  ? 56  SER B OG    1 
ATOM   3625 N  N     . ALA C 1 57  ? 124.150 103.961 112.459 1.00 67.49  ? 57  ALA B N     1 
ATOM   3626 C  CA    . ALA C 1 57  ? 124.387 102.812 113.323 1.00 66.42  ? 57  ALA B CA    1 
ATOM   3627 C  C     . ALA C 1 57  ? 125.130 103.168 114.602 1.00 66.27  ? 57  ALA B C     1 
ATOM   3628 O  O     . ALA C 1 57  ? 125.181 102.338 115.516 1.00 73.52  ? 57  ALA B O     1 
ATOM   3629 C  CB    . ALA C 1 57  ? 125.161 101.736 112.561 1.00 63.34  ? 57  ALA B CB    1 
ATOM   3630 N  N     . GLY C 1 58  ? 125.714 104.364 114.691 1.00 60.27  ? 58  GLY B N     1 
ATOM   3631 C  CA    . GLY C 1 58  ? 126.332 104.786 115.934 1.00 60.16  ? 58  GLY B CA    1 
ATOM   3632 C  C     . GLY C 1 58  ? 125.356 105.258 116.987 1.00 60.96  ? 58  GLY B C     1 
ATOM   3633 O  O     . GLY C 1 58  ? 125.702 105.276 118.172 1.00 69.61  ? 58  GLY B O     1 
ATOM   3634 N  N     . ILE C 1 59  ? 124.147 105.639 116.585 1.00 53.42  ? 59  ILE B N     1 
ATOM   3635 C  CA    . ILE C 1 59  ? 123.125 106.104 117.511 1.00 56.86  ? 59  ILE B CA    1 
ATOM   3636 C  C     . ILE C 1 59  ? 122.223 104.965 117.971 1.00 63.09  ? 59  ILE B C     1 
ATOM   3637 O  O     . ILE C 1 59  ? 121.795 104.939 119.126 1.00 62.75  ? 59  ILE B O     1 
ATOM   3638 C  CB    . ILE C 1 59  ? 122.306 107.241 116.865 1.00 53.20  ? 59  ILE B CB    1 
ATOM   3639 C  CG1   . ILE C 1 59  ? 123.239 108.357 116.400 1.00 55.89  ? 59  ILE B CG1   1 
ATOM   3640 C  CG2   . ILE C 1 59  ? 121.278 107.788 117.837 1.00 56.58  ? 59  ILE B CG2   1 
ATOM   3641 C  CD1   . ILE C 1 59  ? 122.597 109.333 115.453 1.00 60.66  ? 59  ILE B CD1   1 
ATOM   3642 N  N     . ASN C 1 60  ? 121.926 104.015 117.082 1.00 61.99  ? 60  ASN B N     1 
ATOM   3643 C  CA    . ASN C 1 60  ? 121.131 102.859 117.479 1.00 58.10  ? 60  ASN B CA    1 
ATOM   3644 C  C     . ASN C 1 60  ? 121.853 102.029 118.532 1.00 61.27  ? 60  ASN B C     1 
ATOM   3645 O  O     . ASN C 1 60  ? 121.241 101.584 119.509 1.00 67.75  ? 60  ASN B O     1 
ATOM   3646 C  CB    . ASN C 1 60  ? 120.804 102.000 116.259 1.00 62.81  ? 60  ASN B CB    1 
ATOM   3647 C  CG    . ASN C 1 60  ? 120.235 102.808 115.113 1.00 72.10  ? 60  ASN B CG    1 
ATOM   3648 O  OD1   . ASN C 1 60  ? 119.699 103.896 115.311 1.00 75.19  ? 60  ASN B OD1   1 
ATOM   3649 N  ND2   . ASN C 1 60  ? 120.348 102.276 113.902 1.00 69.71  ? 60  ASN B ND2   1 
ATOM   3650 N  N     . GLY C 1 61  ? 123.153 101.809 118.352 1.00 62.09  ? 61  GLY B N     1 
ATOM   3651 C  CA    . GLY C 1 61  ? 123.919 101.027 119.303 1.00 61.41  ? 61  GLY B CA    1 
ATOM   3652 C  C     . GLY C 1 61  ? 124.405 101.784 120.517 1.00 64.75  ? 61  GLY B C     1 
ATOM   3653 O  O     . GLY C 1 61  ? 124.969 101.169 121.426 1.00 67.69  ? 61  GLY B O     1 
ATOM   3654 N  N     . MET C 1 62  ? 124.203 103.098 120.556 1.00 66.16  ? 62  MET B N     1 
ATOM   3655 C  CA    . MET C 1 62  ? 124.640 103.888 121.696 1.00 62.98  ? 62  MET B CA    1 
ATOM   3656 C  C     . MET C 1 62  ? 123.810 103.555 122.929 1.00 58.87  ? 62  MET B C     1 
ATOM   3657 O  O     . MET C 1 62  ? 122.621 103.243 122.839 1.00 59.87  ? 62  MET B O     1 
ATOM   3658 C  CB    . MET C 1 62  ? 124.536 105.379 121.385 1.00 59.42  ? 62  MET B CB    1 
ATOM   3659 C  CG    . MET C 1 62  ? 125.609 106.222 122.049 1.00 64.94  ? 62  MET B CG    1 
ATOM   3660 S  SD    . MET C 1 62  ? 125.877 107.789 121.207 1.00 84.93  ? 62  MET B SD    1 
ATOM   3661 C  CE    . MET C 1 62  ? 124.438 108.700 121.746 1.00 65.19  ? 62  MET B CE    1 
ATOM   3662 N  N     . ASP C 1 63  ? 124.460 103.658 124.081 1.00 57.19  ? 63  ASP B N     1 
ATOM   3663 C  CA    . ASP C 1 63  ? 123.776 103.369 125.358 1.00 60.17  ? 63  ASP B CA    1 
ATOM   3664 C  C     . ASP C 1 63  ? 122.589 104.305 125.467 1.00 65.64  ? 63  ASP B C     1 
ATOM   3665 O  O     . ASP C 1 63  ? 122.746 105.491 125.177 1.00 67.11  ? 63  ASP B O     1 
ATOM   3666 C  CB    . ASP C 1 63  ? 124.714 103.596 126.535 1.00 30.00  ? 63  ASP B CB    1 
ATOM   3667 C  CG    . ASP C 1 63  ? 124.128 103.189 127.873 1.00 30.00  ? 63  ASP B CG    1 
ATOM   3668 O  OD1   . ASP C 1 63  ? 123.200 102.360 127.879 1.00 30.00  ? 63  ASP B OD1   1 
ATOM   3669 O  OD2   . ASP C 1 63  ? 124.615 103.702 128.896 1.00 30.00  ? 63  ASP B OD2   1 
ATOM   3670 N  N     . TYR C 1 64  ? 121.461 103.792 125.919 1.00 62.72  ? 64  TYR B N     1 
ATOM   3671 C  CA    . TYR C 1 64  ? 120.254 104.609 125.959 1.00 55.33  ? 64  TYR B CA    1 
ATOM   3672 C  C     . TYR C 1 64  ? 120.350 105.738 126.975 1.00 51.13  ? 64  TYR B C     1 
ATOM   3673 O  O     . TYR C 1 64  ? 119.737 106.789 126.769 1.00 53.17  ? 64  TYR B O     1 
ATOM   3674 C  CB    . TYR C 1 64  ? 119.035 103.742 126.269 1.00 54.60  ? 64  TYR B CB    1 
ATOM   3675 C  CG    . TYR C 1 64  ? 117.800 104.131 125.487 1.00 57.15  ? 64  TYR B CG    1 
ATOM   3676 C  CD1   . TYR C 1 64  ? 117.674 105.396 124.936 1.00 55.14  ? 64  TYR B CD1   1 
ATOM   3677 C  CD2   . TYR C 1 64  ? 116.757 103.237 125.310 1.00 58.51  ? 64  TYR B CD2   1 
ATOM   3678 C  CE1   . TYR C 1 64  ? 116.552 105.753 124.220 1.00 50.13  ? 64  TYR B CE1   1 
ATOM   3679 C  CE2   . TYR C 1 64  ? 115.629 103.590 124.599 1.00 57.48  ? 64  TYR B CE2   1 
ATOM   3680 C  CZ    . TYR C 1 64  ? 115.534 104.849 124.058 1.00 55.21  ? 64  TYR B CZ    1 
ATOM   3681 O  OH    . TYR C 1 64  ? 114.415 105.207 123.349 1.00 60.84  ? 64  TYR B OH    1 
ATOM   3682 N  N     . ARG C 1 65  ? 121.101 105.553 128.060 1.00 51.90  ? 65  ARG B N     1 
ATOM   3683 C  CA    . ARG C 1 65  ? 121.254 106.618 129.043 1.00 54.59  ? 65  ARG B CA    1 
ATOM   3684 C  C     . ARG C 1 65  ? 122.028 107.810 128.499 1.00 57.91  ? 65  ARG B C     1 
ATOM   3685 O  O     . ARG C 1 65  ? 122.030 108.866 129.138 1.00 59.81  ? 65  ARG B O     1 
ATOM   3686 C  CB    . ARG C 1 65  ? 121.944 106.088 130.300 1.00 61.42  ? 65  ARG B CB    1 
ATOM   3687 C  CG    . ARG C 1 65  ? 121.002 105.430 131.291 1.00 67.54  ? 65  ARG B CG    1 
ATOM   3688 C  CD    . ARG C 1 65  ? 121.763 104.817 132.456 1.00 67.94  ? 65  ARG B CD    1 
ATOM   3689 N  NE    . ARG C 1 65  ? 122.912 104.033 132.022 1.00 62.65  ? 65  ARG B NE    1 
ATOM   3690 C  CZ    . ARG C 1 65  ? 122.838 102.887 131.359 1.00 68.91  ? 65  ARG B CZ    1 
ATOM   3691 N  NH1   . ARG C 1 65  ? 121.674 102.339 131.051 1.00 74.38  ? 65  ARG B NH1   1 
ATOM   3692 N  NH2   . ARG C 1 65  ? 123.961 102.272 131.000 1.00 72.33  ? 65  ARG B NH2   1 
ATOM   3693 N  N     . ASP C 1 66  ? 122.687 107.668 127.350 1.00 55.96  ? 66  ASP B N     1 
ATOM   3694 C  CA    . ASP C 1 66  ? 123.350 108.792 126.703 1.00 52.73  ? 66  ASP B CA    1 
ATOM   3695 C  C     . ASP C 1 66  ? 122.450 109.467 125.677 1.00 56.62  ? 66  ASP B C     1 
ATOM   3696 O  O     . ASP C 1 66  ? 122.539 110.684 125.483 1.00 60.55  ? 66  ASP B O     1 
ATOM   3697 C  CB    . ASP C 1 66  ? 124.646 108.329 126.033 1.00 58.27  ? 66  ASP B CB    1 
ATOM   3698 C  CG    . ASP C 1 66  ? 125.577 107.620 126.995 1.00 73.39  ? 66  ASP B CG    1 
ATOM   3699 O  OD1   . ASP C 1 66  ? 125.520 107.918 128.206 1.00 77.32  ? 66  ASP B OD1   1 
ATOM   3700 O  OD2   . ASP C 1 66  ? 126.368 106.767 126.540 1.00 76.67  ? 66  ASP B OD2   1 
ATOM   3701 N  N     . VAL C 1 67  ? 121.587 108.698 125.011 1.00 53.65  ? 67  VAL B N     1 
ATOM   3702 C  CA    . VAL C 1 67  ? 120.614 109.290 124.099 1.00 51.06  ? 67  VAL B CA    1 
ATOM   3703 C  C     . VAL C 1 67  ? 119.555 110.059 124.881 1.00 52.53  ? 67  VAL B C     1 
ATOM   3704 O  O     . VAL C 1 67  ? 119.185 111.181 124.519 1.00 49.19  ? 67  VAL B O     1 
ATOM   3705 C  CB    . VAL C 1 67  ? 119.985 108.204 123.209 1.00 44.54  ? 67  VAL B CB    1 
ATOM   3706 C  CG1   . VAL C 1 67  ? 119.168 108.840 122.108 1.00 42.78  ? 67  VAL B CG1   1 
ATOM   3707 C  CG2   . VAL C 1 67  ? 121.061 107.311 122.626 1.00 49.30  ? 67  VAL B CG2   1 
ATOM   3708 N  N     . ILE C 1 68  ? 119.054 109.468 125.965 1.00 50.68  ? 68  ILE B N     1 
ATOM   3709 C  CA    . ILE C 1 68  ? 118.112 110.144 126.859 1.00 39.55  ? 68  ILE B CA    1 
ATOM   3710 C  C     . ILE C 1 68  ? 118.960 110.892 127.883 1.00 46.00  ? 68  ILE B C     1 
ATOM   3711 O  O     . ILE C 1 68  ? 119.296 110.376 128.949 1.00 53.98  ? 68  ILE B O     1 
ATOM   3712 C  CB    . ILE C 1 68  ? 117.138 109.172 127.515 1.00 41.34  ? 68  ILE B CB    1 
ATOM   3713 C  CG1   . ILE C 1 68  ? 116.403 108.358 126.455 1.00 41.91  ? 68  ILE B CG1   1 
ATOM   3714 C  CG2   . ILE C 1 68  ? 116.147 109.926 128.375 1.00 44.12  ? 68  ILE B CG2   1 
ATOM   3715 C  CD1   . ILE C 1 68  ? 115.748 109.195 125.394 1.00 47.94  ? 68  ILE B CD1   1 
ATOM   3716 N  N     . GLY C 1 69  ? 119.304 112.129 127.551 1.00 43.70  ? 69  GLY B N     1 
ATOM   3717 C  CA    . GLY C 1 69  ? 120.202 112.914 128.370 1.00 49.34  ? 69  GLY B CA    1 
ATOM   3718 C  C     . GLY C 1 69  ? 121.104 113.759 127.502 1.00 51.37  ? 69  GLY B C     1 
ATOM   3719 O  O     . GLY C 1 69  ? 121.798 114.654 127.990 1.00 56.26  ? 69  GLY B O     1 
ATOM   3720 N  N     . ARG C 1 70  ? 121.112 113.463 126.204 1.00 41.52  ? 70  ARG B N     1 
ATOM   3721 C  CA    . ARG C 1 70  ? 121.745 114.364 125.244 1.00 44.59  ? 70  ARG B CA    1 
ATOM   3722 C  C     . ARG C 1 70  ? 121.048 115.716 125.158 1.00 50.42  ? 70  ARG B C     1 
ATOM   3723 O  O     . ARG C 1 70  ? 121.749 116.743 125.141 1.00 61.19  ? 70  ARG B O     1 
ATOM   3724 C  CB    . ARG C 1 70  ? 121.825 113.687 123.873 1.00 45.36  ? 70  ARG B CB    1 
ATOM   3725 C  CG    . ARG C 1 70  ? 122.501 114.530 122.812 1.00 48.66  ? 70  ARG B CG    1 
ATOM   3726 C  CD    . ARG C 1 70  ? 123.931 114.851 123.195 1.00 50.37  ? 70  ARG B CD    1 
ATOM   3727 N  NE    . ARG C 1 70  ? 124.760 113.655 123.253 1.00 56.44  ? 70  ARG B NE    1 
ATOM   3728 C  CZ    . ARG C 1 70  ? 125.694 113.350 122.364 1.00 61.38  ? 70  ARG B CZ    1 
ATOM   3729 N  NH1   . ARG C 1 70  ? 125.945 114.134 121.329 1.00 59.21  ? 70  ARG B NH1   1 
ATOM   3730 N  NH2   . ARG C 1 70  ? 126.396 112.231 122.519 1.00 66.65  ? 70  ARG B NH2   1 
ATOM   3731 N  N     . PRO C 1 71  ? 119.711 115.806 125.073 1.00 45.87  ? 71  PRO B N     1 
ATOM   3732 C  CA    . PRO C 1 71  ? 119.088 117.140 125.024 1.00 38.72  ? 71  PRO B CA    1 
ATOM   3733 C  C     . PRO C 1 71  ? 119.395 118.000 126.234 1.00 44.46  ? 71  PRO B C     1 
ATOM   3734 O  O     . PRO C 1 71  ? 119.552 119.217 126.092 1.00 54.89  ? 71  PRO B O     1 
ATOM   3735 C  CB    . PRO C 1 71  ? 117.593 116.822 124.924 1.00 39.09  ? 71  PRO B CB    1 
ATOM   3736 C  CG    . PRO C 1 71  ? 117.533 115.479 124.338 1.00 44.36  ? 71  PRO B CG    1 
ATOM   3737 C  CD    . PRO C 1 71  ? 118.705 114.745 124.894 1.00 51.82  ? 71  PRO B CD    1 
ATOM   3738 N  N     . VAL C 1 72  ? 119.482 117.409 127.426 1.00 44.05  ? 72  VAL B N     1 
ATOM   3739 C  CA    . VAL C 1 72  ? 119.805 118.202 128.607 1.00 48.69  ? 72  VAL B CA    1 
ATOM   3740 C  C     . VAL C 1 72  ? 121.234 118.724 128.526 1.00 50.78  ? 72  VAL B C     1 
ATOM   3741 O  O     . VAL C 1 72  ? 121.515 119.861 128.922 1.00 48.80  ? 72  VAL B O     1 
ATOM   3742 C  CB    . VAL C 1 72  ? 119.570 117.383 129.887 1.00 41.01  ? 72  VAL B CB    1 
ATOM   3743 C  CG1   . VAL C 1 72  ? 119.615 118.289 131.099 1.00 32.77  ? 72  VAL B CG1   1 
ATOM   3744 C  CG2   . VAL C 1 72  ? 118.239 116.661 129.812 1.00 40.68  ? 72  VAL B CG2   1 
ATOM   3745 N  N     . GLU C 1 73  ? 122.156 117.910 128.006 1.00 49.22  ? 73  GLU B N     1 
ATOM   3746 C  CA    . GLU C 1 73  ? 123.521 118.380 127.795 1.00 47.24  ? 73  GLU B CA    1 
ATOM   3747 C  C     . GLU C 1 73  ? 123.556 119.524 126.793 1.00 47.00  ? 73  GLU B C     1 
ATOM   3748 O  O     . GLU C 1 73  ? 124.270 120.514 126.992 1.00 56.39  ? 73  GLU B O     1 
ATOM   3749 C  CB    . GLU C 1 73  ? 124.408 117.232 127.319 1.00 46.31  ? 73  GLU B CB    1 
ATOM   3750 C  CG    . GLU C 1 73  ? 124.567 116.103 128.316 1.00 57.84  ? 73  GLU B CG    1 
ATOM   3751 C  CD    . GLU C 1 73  ? 125.637 115.116 127.900 1.00 74.38  ? 73  GLU B CD    1 
ATOM   3752 O  OE1   . GLU C 1 73  ? 126.416 115.438 126.979 1.00 77.35  ? 73  GLU B OE1   1 
ATOM   3753 O  OE2   . GLU C 1 73  ? 125.697 114.017 128.489 1.00 81.47  ? 73  GLU B OE2   1 
ATOM   3754 N  N     . ASN C 1 74  ? 122.791 119.404 125.706 1.00 43.01  ? 74  ASN B N     1 
ATOM   3755 C  CA    . ASN C 1 74  ? 122.741 120.474 124.717 1.00 45.76  ? 74  ASN B CA    1 
ATOM   3756 C  C     . ASN C 1 74  ? 122.177 121.753 125.319 1.00 48.29  ? 74  ASN B C     1 
ATOM   3757 O  O     . ASN C 1 74  ? 122.687 122.847 125.058 1.00 61.14  ? 74  ASN B O     1 
ATOM   3758 C  CB    . ASN C 1 74  ? 121.913 120.039 123.510 1.00 44.34  ? 74  ASN B CB    1 
ATOM   3759 C  CG    . ASN C 1 74  ? 122.600 118.972 122.692 1.00 47.16  ? 74  ASN B CG    1 
ATOM   3760 O  OD1   . ASN C 1 74  ? 121.998 118.377 121.802 1.00 48.91  ? 74  ASN B OD1   1 
ATOM   3761 N  ND2   . ASN C 1 74  ? 123.865 118.719 122.992 1.00 48.41  ? 74  ASN B ND2   1 
ATOM   3762 N  N     . ALA C 1 75  ? 121.129 121.636 126.134 1.00 41.20  ? 75  ALA B N     1 
ATOM   3763 C  CA    . ALA C 1 75  ? 120.547 122.815 126.766 1.00 41.48  ? 75  ALA B CA    1 
ATOM   3764 C  C     . ALA C 1 75  ? 121.517 123.460 127.743 1.00 47.80  ? 75  ALA B C     1 
ATOM   3765 O  O     . ALA C 1 75  ? 121.621 124.689 127.798 1.00 56.02  ? 75  ALA B O     1 
ATOM   3766 C  CB    . ALA C 1 75  ? 119.254 122.448 127.480 1.00 40.58  ? 75  ALA B CB    1 
ATOM   3767 N  N     . VAL C 1 76  ? 122.226 122.651 128.532 1.00 41.76  ? 76  VAL B N     1 
ATOM   3768 C  CA    . VAL C 1 76  ? 123.187 123.204 129.481 1.00 42.49  ? 76  VAL B CA    1 
ATOM   3769 C  C     . VAL C 1 76  ? 124.314 123.914 128.745 1.00 50.59  ? 76  VAL B C     1 
ATOM   3770 O  O     . VAL C 1 76  ? 124.732 125.012 129.133 1.00 52.50  ? 76  VAL B O     1 
ATOM   3771 C  CB    . VAL C 1 76  ? 123.722 122.098 130.407 1.00 43.22  ? 76  VAL B CB    1 
ATOM   3772 C  CG1   . VAL C 1 76  ? 124.986 122.560 131.104 1.00 48.67  ? 76  VAL B CG1   1 
ATOM   3773 C  CG2   . VAL C 1 76  ? 122.666 121.709 131.422 1.00 44.15  ? 76  VAL B CG2   1 
ATOM   3774 N  N     . THR C 1 77  ? 124.819 123.306 127.668 1.00 50.90  ? 77  THR B N     1 
ATOM   3775 C  CA    . THR C 1 77  ? 125.876 123.948 126.894 1.00 44.30  ? 77  THR B CA    1 
ATOM   3776 C  C     . THR C 1 77  ? 125.389 125.244 126.260 1.00 49.93  ? 77  THR B C     1 
ATOM   3777 O  O     . THR C 1 77  ? 126.106 126.252 126.261 1.00 64.60  ? 77  THR B O     1 
ATOM   3778 C  CB    . THR C 1 77  ? 126.401 122.996 125.823 1.00 42.28  ? 77  THR B CB    1 
ATOM   3779 O  OG1   . THR C 1 77  ? 126.620 121.703 126.396 1.00 54.68  ? 77  THR B OG1   1 
ATOM   3780 C  CG2   . THR C 1 77  ? 127.710 123.513 125.262 1.00 49.43  ? 77  THR B CG2   1 
ATOM   3781 N  N     . GLU C 1 78  ? 124.168 125.241 125.719 1.00 46.57  ? 78  GLU B N     1 
ATOM   3782 C  CA    . GLU C 1 78  ? 123.623 126.450 125.112 1.00 46.18  ? 78  GLU B CA    1 
ATOM   3783 C  C     . GLU C 1 78  ? 123.450 127.557 126.143 1.00 49.29  ? 78  GLU B C     1 
ATOM   3784 O  O     . GLU C 1 78  ? 123.789 128.718 125.883 1.00 61.11  ? 78  GLU B O     1 
ATOM   3785 C  CB    . GLU C 1 78  ? 122.292 126.132 124.434 1.00 46.29  ? 78  GLU B CB    1 
ATOM   3786 C  CG    . GLU C 1 78  ? 121.757 127.240 123.552 1.00 52.76  ? 78  GLU B CG    1 
ATOM   3787 C  CD    . GLU C 1 78  ? 120.632 128.011 124.205 1.00 62.33  ? 78  GLU B CD    1 
ATOM   3788 O  OE1   . GLU C 1 78  ? 120.577 128.050 125.451 1.00 61.48  ? 78  GLU B OE1   1 
ATOM   3789 O  OE2   . GLU C 1 78  ? 119.802 128.582 123.470 1.00 64.65  ? 78  GLU B OE2   1 
ATOM   3790 N  N     . GLY C 1 79  ? 122.923 127.218 127.320 1.00 44.41  ? 79  GLY B N     1 
ATOM   3791 C  CA    . GLY C 1 79  ? 122.753 128.219 128.358 1.00 50.26  ? 79  GLY B CA    1 
ATOM   3792 C  C     . GLY C 1 79  ? 124.073 128.769 128.858 1.00 54.16  ? 79  GLY B C     1 
ATOM   3793 O  O     . GLY C 1 79  ? 124.194 129.966 129.130 1.00 58.10  ? 79  GLY B O     1 
ATOM   3794 N  N     . THR C 1 80  ? 125.080 127.904 128.992 1.00 49.93  ? 80  THR B N     1 
ATOM   3795 C  CA    . THR C 1 80  ? 126.408 128.377 129.365 1.00 48.70  ? 80  THR B CA    1 
ATOM   3796 C  C     . THR C 1 80  ? 126.971 129.307 128.300 1.00 53.21  ? 80  THR B C     1 
ATOM   3797 O  O     . THR C 1 80  ? 127.615 130.313 128.618 1.00 60.97  ? 80  THR B O     1 
ATOM   3798 C  CB    . THR C 1 80  ? 127.342 127.190 129.592 1.00 45.92  ? 80  THR B CB    1 
ATOM   3799 O  OG1   . THR C 1 80  ? 126.835 126.379 130.658 1.00 54.31  ? 80  THR B OG1   1 
ATOM   3800 C  CG2   . THR C 1 80  ? 128.733 127.669 129.957 1.00 46.09  ? 80  THR B CG2   1 
ATOM   3801 N  N     . HIS C 1 81  ? 126.737 128.986 127.026 1.00 53.10  ? 81  HIS B N     1 
ATOM   3802 C  CA    . HIS C 1 81  ? 127.219 129.838 125.945 1.00 55.31  ? 81  HIS B CA    1 
ATOM   3803 C  C     . HIS C 1 81  ? 126.544 131.203 125.965 1.00 61.10  ? 81  HIS B C     1 
ATOM   3804 O  O     . HIS C 1 81  ? 127.200 132.230 125.760 1.00 72.24  ? 81  HIS B O     1 
ATOM   3805 C  CB    . HIS C 1 81  ? 126.995 129.149 124.600 1.00 57.15  ? 81  HIS B CB    1 
ATOM   3806 C  CG    . HIS C 1 81  ? 126.981 130.087 123.434 1.00 69.05  ? 81  HIS B CG    1 
ATOM   3807 N  ND1   . HIS C 1 81  ? 125.832 130.394 122.739 1.00 69.41  ? 81  HIS B ND1   1 
ATOM   3808 C  CD2   . HIS C 1 81  ? 127.977 130.789 122.842 1.00 73.31  ? 81  HIS B CD2   1 
ATOM   3809 C  CE1   . HIS C 1 81  ? 126.119 131.242 121.768 1.00 73.01  ? 81  HIS B CE1   1 
ATOM   3810 N  NE2   . HIS C 1 81  ? 127.414 131.499 121.809 1.00 75.30  ? 81  HIS B NE2   1 
ATOM   3811 N  N     . PHE C 1 82  ? 125.234 131.239 126.211 1.00 59.76  ? 82  PHE B N     1 
ATOM   3812 C  CA    . PHE C 1 82  ? 124.512 132.507 126.160 1.00 60.08  ? 82  PHE B CA    1 
ATOM   3813 C  C     . PHE C 1 82  ? 124.665 133.293 127.459 1.00 64.11  ? 82  PHE B C     1 
ATOM   3814 O  O     . PHE C 1 82  ? 125.218 134.398 127.465 1.00 73.98  ? 82  PHE B O     1 
ATOM   3815 C  CB    . PHE C 1 82  ? 123.033 132.259 125.854 1.00 62.37  ? 82  PHE B CB    1 
ATOM   3816 C  CG    . PHE C 1 82  ? 122.730 132.158 124.389 1.00 66.05  ? 82  PHE B CG    1 
ATOM   3817 C  CD1   . PHE C 1 82  ? 123.218 133.102 123.505 1.00 67.80  ? 82  PHE B CD1   1 
ATOM   3818 C  CD2   . PHE C 1 82  ? 121.958 131.124 123.896 1.00 68.25  ? 82  PHE B CD2   1 
ATOM   3819 C  CE1   . PHE C 1 82  ? 122.944 133.013 122.156 1.00 72.68  ? 82  PHE B CE1   1 
ATOM   3820 C  CE2   . PHE C 1 82  ? 121.680 131.031 122.548 1.00 67.73  ? 82  PHE B CE2   1 
ATOM   3821 C  CZ    . PHE C 1 82  ? 122.175 131.977 121.677 1.00 70.63  ? 82  PHE B CZ    1 
ATOM   3822 N  N     . PHE C 1 83  ? 124.174 132.740 128.568 1.00 62.24  ? 83  PHE B N     1 
ATOM   3823 C  CA    . PHE C 1 83  ? 124.254 133.396 129.874 1.00 58.99  ? 83  PHE B CA    1 
ATOM   3824 C  C     . PHE C 1 83  ? 125.417 132.790 130.655 1.00 63.39  ? 83  PHE B C     1 
ATOM   3825 O  O     . PHE C 1 83  ? 125.240 131.979 131.563 1.00 65.53  ? 83  PHE B O     1 
ATOM   3826 C  CB    . PHE C 1 83  ? 122.935 133.254 130.625 1.00 56.09  ? 83  PHE B CB    1 
ATOM   3827 C  CG    . PHE C 1 83  ? 121.739 133.114 129.731 1.00 56.14  ? 83  PHE B CG    1 
ATOM   3828 C  CD1   . PHE C 1 83  ? 121.141 134.229 129.173 1.00 60.38  ? 83  PHE B CD1   1 
ATOM   3829 C  CD2   . PHE C 1 83  ? 121.212 131.868 129.449 1.00 53.98  ? 83  PHE B CD2   1 
ATOM   3830 C  CE1   . PHE C 1 83  ? 120.040 134.101 128.352 1.00 59.60  ? 83  PHE B CE1   1 
ATOM   3831 C  CE2   . PHE C 1 83  ? 120.113 131.736 128.628 1.00 57.66  ? 83  PHE B CE2   1 
ATOM   3832 C  CZ    . PHE C 1 83  ? 119.526 132.853 128.079 1.00 60.85  ? 83  PHE B CZ    1 
ATOM   3833 N  N     . ARG C 1 84  ? 126.628 133.199 130.289 1.00 65.58  ? 84  ARG B N     1 
ATOM   3834 C  CA    . ARG C 1 84  ? 127.815 132.680 130.950 1.00 66.20  ? 84  ARG B CA    1 
ATOM   3835 C  C     . ARG C 1 84  ? 127.899 133.188 132.384 1.00 71.92  ? 84  ARG B C     1 
ATOM   3836 O  O     . ARG C 1 84  ? 127.454 134.293 132.702 1.00 77.92  ? 84  ARG B O     1 
ATOM   3837 C  CB    . ARG C 1 84  ? 129.070 133.082 130.181 1.00 71.70  ? 84  ARG B CB    1 
ATOM   3838 C  CG    . ARG C 1 84  ? 129.190 134.576 129.938 1.00 69.66  ? 84  ARG B CG    1 
ATOM   3839 C  CD    . ARG C 1 84  ? 130.274 134.885 128.924 1.00 75.31  ? 84  ARG B CD    1 
ATOM   3840 N  NE    . ARG C 1 84  ? 129.854 134.588 127.560 1.00 81.77  ? 84  ARG B NE    1 
ATOM   3841 C  CZ    . ARG C 1 84  ? 130.170 133.481 126.903 1.00 83.04  ? 84  ARG B CZ    1 
ATOM   3842 N  NH1   . ARG C 1 84  ? 130.907 132.532 127.459 1.00 76.95  ? 84  ARG B NH1   1 
ATOM   3843 N  NH2   . ARG C 1 84  ? 129.738 133.321 125.656 1.00 80.21  ? 84  ARG B NH2   1 
ATOM   3844 N  N     . ASP C 1 85  ? 128.466 132.356 133.257 1.00 78.11  ? 85  ASP B N     1 
ATOM   3845 C  CA    . ASP C 1 85  ? 128.695 132.664 134.667 1.00 86.00  ? 85  ASP B CA    1 
ATOM   3846 C  C     . ASP C 1 85  ? 127.406 132.958 135.424 1.00 78.12  ? 85  ASP B C     1 
ATOM   3847 O  O     . ASP C 1 85  ? 127.456 133.386 136.582 1.00 82.88  ? 85  ASP B O     1 
ATOM   3848 C  CB    . ASP C 1 85  ? 129.672 133.837 134.832 1.00 93.22  ? 85  ASP B CB    1 
ATOM   3849 C  CG    . ASP C 1 85  ? 130.470 133.756 136.118 1.00 101.83 ? 85  ASP B CG    1 
ATOM   3850 O  OD1   . ASP C 1 85  ? 130.205 132.842 136.927 1.00 106.33 ? 85  ASP B OD1   1 
ATOM   3851 O  OD2   . ASP C 1 85  ? 131.362 134.606 136.319 1.00 102.75 ? 85  ASP B OD2   1 
ATOM   3852 N  N     . ASP C 1 86  ? 126.252 132.736 134.801 1.00 70.59  ? 86  ASP B N     1 
ATOM   3853 C  CA    . ASP C 1 86  ? 124.968 133.085 135.382 1.00 69.62  ? 86  ASP B CA    1 
ATOM   3854 C  C     . ASP C 1 86  ? 123.963 131.950 135.240 1.00 70.56  ? 86  ASP B C     1 
ATOM   3855 O  O     . ASP C 1 86  ? 122.966 131.928 135.969 1.00 67.47  ? 86  ASP B O     1 
ATOM   3856 C  CB    . ASP C 1 86  ? 124.428 134.358 134.702 1.00 64.96  ? 86  ASP B CB    1 
ATOM   3857 C  CG    . ASP C 1 86  ? 123.246 134.986 135.426 1.00 74.21  ? 86  ASP B CG    1 
ATOM   3858 O  OD1   . ASP C 1 86  ? 122.673 134.380 136.349 1.00 82.11  ? 86  ASP B OD1   1 
ATOM   3859 O  OD2   . ASP C 1 86  ? 122.883 136.120 135.052 1.00 76.43  ? 86  ASP B OD2   1 
ATOM   3860 N  N     . PHE C 1 87  ? 124.223 130.982 134.370 1.00 66.64  ? 87  PHE B N     1 
ATOM   3861 C  CA    . PHE C 1 87  ? 123.292 129.900 134.093 1.00 53.70  ? 87  PHE B CA    1 
ATOM   3862 C  C     . PHE C 1 87  ? 123.296 128.896 135.237 1.00 61.35  ? 87  PHE B C     1 
ATOM   3863 O  O     . PHE C 1 87  ? 124.361 128.475 135.698 1.00 68.73  ? 87  PHE B O     1 
ATOM   3864 C  CB    . PHE C 1 87  ? 123.667 129.210 132.783 1.00 46.97  ? 87  PHE B CB    1 
ATOM   3865 C  CG    . PHE C 1 87  ? 122.703 128.147 132.358 1.00 45.80  ? 87  PHE B CG    1 
ATOM   3866 C  CD1   . PHE C 1 87  ? 121.582 128.471 131.621 1.00 45.37  ? 87  PHE B CD1   1 
ATOM   3867 C  CD2   . PHE C 1 87  ? 122.922 126.822 132.684 1.00 53.01  ? 87  PHE B CD2   1 
ATOM   3868 C  CE1   . PHE C 1 87  ? 120.696 127.497 131.223 1.00 42.54  ? 87  PHE B CE1   1 
ATOM   3869 C  CE2   . PHE C 1 87  ? 122.035 125.846 132.288 1.00 54.17  ? 87  PHE B CE2   1 
ATOM   3870 C  CZ    . PHE C 1 87  ? 120.923 126.184 131.554 1.00 42.63  ? 87  PHE B CZ    1 
ATOM   3871 N  N     . ARG C 1 88  ? 122.103 128.513 135.687 1.00 60.02  ? 88  ARG B N     1 
ATOM   3872 C  CA    . ARG C 1 88  ? 121.959 127.491 136.716 1.00 56.88  ? 88  ARG B CA    1 
ATOM   3873 C  C     . ARG C 1 88  ? 120.526 126.989 136.707 1.00 56.49  ? 88  ARG B C     1 
ATOM   3874 O  O     . ARG C 1 88  ? 119.590 127.788 136.785 1.00 61.04  ? 88  ARG B O     1 
ATOM   3875 C  CB    . ARG C 1 88  ? 122.320 128.034 138.100 1.00 60.39  ? 88  ARG B CB    1 
ATOM   3876 C  CG    . ARG C 1 88  ? 122.977 127.006 139.004 1.00 69.49  ? 88  ARG B CG    1 
ATOM   3877 C  CD    . ARG C 1 88  ? 122.597 127.218 140.459 1.00 77.62  ? 88  ARG B CD    1 
ATOM   3878 N  NE    . ARG C 1 88  ? 121.153 127.309 140.636 1.00 78.71  ? 88  ARG B NE    1 
ATOM   3879 C  CZ    . ARG C 1 88  ? 120.391 126.328 141.099 1.00 72.70  ? 88  ARG B CZ    1 
ATOM   3880 N  NH1   . ARG C 1 88  ? 120.903 125.155 141.436 1.00 65.35  ? 88  ARG B NH1   1 
ATOM   3881 N  NH2   . ARG C 1 88  ? 119.083 126.527 141.226 1.00 73.77  ? 88  ARG B NH2   1 
ATOM   3882 N  N     . VAL C 1 89  ? 120.361 125.672 136.604 1.00 58.72  ? 89  VAL B N     1 
ATOM   3883 C  CA    . VAL C 1 89  ? 119.055 125.027 136.660 1.00 56.64  ? 89  VAL B CA    1 
ATOM   3884 C  C     . VAL C 1 89  ? 119.091 123.963 137.745 1.00 59.53  ? 89  VAL B C     1 
ATOM   3885 O  O     . VAL C 1 89  ? 120.007 123.134 137.777 1.00 66.02  ? 89  VAL B O     1 
ATOM   3886 C  CB    . VAL C 1 89  ? 118.660 124.404 135.311 1.00 46.86  ? 89  VAL B CB    1 
ATOM   3887 C  CG1   . VAL C 1 89  ? 117.205 123.997 135.342 1.00 51.27  ? 89  VAL B CG1   1 
ATOM   3888 C  CG2   . VAL C 1 89  ? 118.905 125.381 134.187 1.00 44.80  ? 89  VAL B CG2   1 
ATOM   3889 N  N     . ASP C 1 90  ? 118.097 123.987 138.628 1.00 58.88  ? 90  ASP B N     1 
ATOM   3890 C  CA    . ASP C 1 90  ? 118.022 122.998 139.692 1.00 61.41  ? 90  ASP B CA    1 
ATOM   3891 C  C     . ASP C 1 90  ? 117.812 121.610 139.105 1.00 55.97  ? 90  ASP B C     1 
ATOM   3892 O  O     . ASP C 1 90  ? 117.121 121.443 138.098 1.00 53.26  ? 90  ASP B O     1 
ATOM   3893 C  CB    . ASP C 1 90  ? 116.886 123.339 140.656 1.00 66.60  ? 90  ASP B CB    1 
ATOM   3894 C  CG    . ASP C 1 90  ? 117.271 123.129 142.107 1.00 72.98  ? 90  ASP B CG    1 
ATOM   3895 O  OD1   . ASP C 1 90  ? 117.744 122.024 142.447 1.00 72.67  ? 90  ASP B OD1   1 
ATOM   3896 O  OD2   . ASP C 1 90  ? 117.098 124.069 142.910 1.00 78.21  ? 90  ASP B OD2   1 
ATOM   3897 N  N     . SER C 1 91  ? 118.417 120.608 139.747 1.00 55.15  ? 91  SER B N     1 
ATOM   3898 C  CA    . SER C 1 91  ? 118.323 119.239 139.254 1.00 57.73  ? 91  SER B CA    1 
ATOM   3899 C  C     . SER C 1 91  ? 116.889 118.731 139.231 1.00 57.72  ? 91  SER B C     1 
ATOM   3900 O  O     . SER C 1 91  ? 116.590 117.780 138.499 1.00 55.61  ? 91  SER B O     1 
ATOM   3901 C  CB    . SER C 1 91  ? 119.191 118.316 140.108 1.00 62.40  ? 91  SER B CB    1 
ATOM   3902 O  OG    . SER C 1 91  ? 119.357 117.056 139.485 1.00 66.46  ? 91  SER B OG    1 
ATOM   3903 N  N     . ASN C 1 92  ? 115.994 119.350 140.003 1.00 53.62  ? 92  ASN B N     1 
ATOM   3904 C  CA    . ASN C 1 92  ? 114.588 118.973 139.987 1.00 46.70  ? 92  ASN B CA    1 
ATOM   3905 C  C     . ASN C 1 92  ? 113.879 119.406 138.711 1.00 44.54  ? 92  ASN B C     1 
ATOM   3906 O  O     . ASN C 1 92  ? 112.739 118.989 138.486 1.00 45.55  ? 92  ASN B O     1 
ATOM   3907 C  CB    . ASN C 1 92  ? 113.881 119.561 141.206 1.00 43.77  ? 92  ASN B CB    1 
ATOM   3908 C  CG    . ASN C 1 92  ? 114.201 118.811 142.481 1.00 46.38  ? 92  ASN B CG    1 
ATOM   3909 O  OD1   . ASN C 1 92  ? 114.071 117.590 142.544 1.00 52.58  ? 92  ASN B OD1   1 
ATOM   3910 N  ND2   . ASN C 1 92  ? 114.619 119.539 143.508 1.00 44.89  ? 92  ASN B ND2   1 
ATOM   3911 N  N     . ALA C 1 93  ? 114.516 120.231 137.881 1.00 39.79  ? 93  ALA B N     1 
ATOM   3912 C  CA    . ALA C 1 93  ? 114.009 120.524 136.547 1.00 39.23  ? 93  ALA B CA    1 
ATOM   3913 C  C     . ALA C 1 93  ? 114.600 119.589 135.506 1.00 46.39  ? 93  ALA B C     1 
ATOM   3914 O  O     . ALA C 1 93  ? 113.895 119.152 134.587 1.00 49.66  ? 93  ALA B O     1 
ATOM   3915 C  CB    . ALA C 1 93  ? 114.317 121.971 136.166 1.00 42.14  ? 93  ALA B CB    1 
ATOM   3916 N  N     . LYS C 1 94  ? 115.891 119.279 135.642 1.00 49.78  ? 94  LYS B N     1 
ATOM   3917 C  CA    . LYS C 1 94  ? 116.525 118.320 134.749 1.00 43.07  ? 94  LYS B CA    1 
ATOM   3918 C  C     . LYS C 1 94  ? 115.880 116.949 134.874 1.00 42.52  ? 94  LYS B C     1 
ATOM   3919 O  O     . LYS C 1 94  ? 115.745 116.230 133.881 1.00 44.80  ? 94  LYS B O     1 
ATOM   3920 C  CB    . LYS C 1 94  ? 118.020 118.238 135.042 1.00 39.61  ? 94  LYS B CB    1 
ATOM   3921 C  CG    . LYS C 1 94  ? 118.808 119.436 134.558 1.00 46.63  ? 94  LYS B CG    1 
ATOM   3922 C  CD    . LYS C 1 94  ? 120.176 119.485 135.206 1.00 46.54  ? 94  LYS B CD    1 
ATOM   3923 C  CE    . LYS C 1 94  ? 120.925 120.744 134.815 1.00 46.37  ? 94  LYS B CE    1 
ATOM   3924 N  NZ    . LYS C 1 94  ? 122.165 120.915 135.618 1.00 49.27  ? 94  LYS B NZ    1 
ATOM   3925 N  N     . ALA C 1 95  ? 115.462 116.573 136.084 1.00 45.15  ? 95  ALA B N     1 
ATOM   3926 C  CA    . ALA C 1 95  ? 114.793 115.289 136.267 1.00 46.52  ? 95  ALA B CA    1 
ATOM   3927 C  C     . ALA C 1 95  ? 113.481 115.231 135.489 1.00 44.38  ? 95  ALA B C     1 
ATOM   3928 O  O     . ALA C 1 95  ? 113.228 114.278 134.740 1.00 42.93  ? 95  ALA B O     1 
ATOM   3929 C  CB    . ALA C 1 95  ? 114.553 115.036 137.753 1.00 41.49  ? 95  ALA B CB    1 
ATOM   3930 N  N     . LYS C 1 96  ? 112.633 116.248 135.656 1.00 40.32  ? 96  LYS B N     1 
ATOM   3931 C  CA    . LYS C 1 96  ? 111.356 116.288 134.949 1.00 39.83  ? 96  LYS B CA    1 
ATOM   3932 C  C     . LYS C 1 96  ? 111.567 116.289 133.443 1.00 45.65  ? 96  LYS B C     1 
ATOM   3933 O  O     . LYS C 1 96  ? 110.890 115.561 132.701 1.00 46.22  ? 96  LYS B O     1 
ATOM   3934 C  CB    . LYS C 1 96  ? 110.570 117.529 135.372 1.00 37.86  ? 96  LYS B CB    1 
ATOM   3935 C  CG    . LYS C 1 96  ? 109.134 117.560 134.890 1.00 40.90  ? 96  LYS B CG    1 
ATOM   3936 C  CD    . LYS C 1 96  ? 108.960 118.486 133.707 1.00 43.87  ? 96  LYS B CD    1 
ATOM   3937 C  CE    . LYS C 1 96  ? 107.501 118.581 133.310 1.00 51.16  ? 96  LYS B CE    1 
ATOM   3938 N  NZ    . LYS C 1 96  ? 107.323 118.637 131.836 1.00 52.73  ? 96  LYS B NZ    1 
ATOM   3939 N  N     . VAL C 1 97  ? 112.505 117.109 132.973 1.00 47.28  ? 97  VAL B N     1 
ATOM   3940 C  CA    . VAL C 1 97  ? 112.750 117.217 131.542 1.00 41.79  ? 97  VAL B CA    1 
ATOM   3941 C  C     . VAL C 1 97  ? 113.278 115.902 130.984 1.00 46.10  ? 97  VAL B C     1 
ATOM   3942 O  O     . VAL C 1 97  ? 112.874 115.473 129.898 1.00 49.90  ? 97  VAL B O     1 
ATOM   3943 C  CB    . VAL C 1 97  ? 113.710 118.385 131.269 1.00 39.13  ? 97  VAL B CB    1 
ATOM   3944 C  CG1   . VAL C 1 97  ? 114.497 118.122 130.030 1.00 44.42  ? 97  VAL B CG1   1 
ATOM   3945 C  CG2   . VAL C 1 97  ? 112.929 119.678 131.138 1.00 41.19  ? 97  VAL B CG2   1 
ATOM   3946 N  N     . ALA C 1 98  ? 114.178 115.237 131.713 1.00 44.06  ? 98  ALA B N     1 
ATOM   3947 C  CA    . ALA C 1 98  ? 114.710 113.961 131.251 1.00 41.04  ? 98  ALA B CA    1 
ATOM   3948 C  C     . ALA C 1 98  ? 113.623 112.899 131.199 1.00 42.51  ? 98  ALA B C     1 
ATOM   3949 O  O     . ALA C 1 98  ? 113.587 112.085 130.270 1.00 50.50  ? 98  ALA B O     1 
ATOM   3950 C  CB    . ALA C 1 98  ? 115.857 113.514 132.153 1.00 46.78  ? 98  ALA B CB    1 
ATOM   3951 N  N     . GLY C 1 99  ? 112.726 112.891 132.185 1.00 37.33  ? 99  GLY B N     1 
ATOM   3952 C  CA    . GLY C 1 99  ? 111.622 111.944 132.142 1.00 42.60  ? 99  GLY B CA    1 
ATOM   3953 C  C     . GLY C 1 99  ? 110.714 112.167 130.948 1.00 44.10  ? 99  GLY B C     1 
ATOM   3954 O  O     . GLY C 1 99  ? 110.335 111.221 130.248 1.00 48.51  ? 99  GLY B O     1 
ATOM   3955 N  N     . ASP C 1 100 ? 110.358 113.428 130.692 1.00 40.63  ? 100 ASP B N     1 
ATOM   3956 C  CA    . ASP C 1 100 ? 109.495 113.725 129.552 1.00 40.11  ? 100 ASP B CA    1 
ATOM   3957 C  C     . ASP C 1 100 ? 110.185 113.404 128.231 1.00 43.89  ? 100 ASP B C     1 
ATOM   3958 O  O     . ASP C 1 100 ? 109.544 112.921 127.288 1.00 49.51  ? 100 ASP B O     1 
ATOM   3959 C  CB    . ASP C 1 100 ? 109.058 115.187 129.591 1.00 45.69  ? 100 ASP B CB    1 
ATOM   3960 C  CG    . ASP C 1 100 ? 107.796 115.391 130.401 1.00 59.34  ? 100 ASP B CG    1 
ATOM   3961 O  OD1   . ASP C 1 100 ? 107.143 114.383 130.743 1.00 61.92  ? 100 ASP B OD1   1 
ATOM   3962 O  OD2   . ASP C 1 100 ? 107.457 116.555 130.696 1.00 65.77  ? 100 ASP B OD2   1 
ATOM   3963 N  N     . ILE C 1 101 ? 111.489 113.666 128.141 1.00 45.43  ? 101 ILE B N     1 
ATOM   3964 C  CA    . ILE C 1 101 ? 112.231 113.351 126.926 1.00 41.54  ? 101 ILE B CA    1 
ATOM   3965 C  C     . ILE C 1 101 ? 112.290 111.846 126.712 1.00 39.67  ? 101 ILE B C     1 
ATOM   3966 O  O     . ILE C 1 101 ? 112.149 111.366 125.585 1.00 44.61  ? 101 ILE B O     1 
ATOM   3967 C  CB    . ILE C 1 101 ? 113.634 113.978 126.982 1.00 38.95  ? 101 ILE B CB    1 
ATOM   3968 C  CG1   . ILE C 1 101 ? 113.548 115.471 126.680 1.00 35.81  ? 101 ILE B CG1   1 
ATOM   3969 C  CG2   . ILE C 1 101 ? 114.569 113.301 126.001 1.00 35.96  ? 101 ILE B CG2   1 
ATOM   3970 C  CD1   . ILE C 1 101 ? 114.797 116.216 127.014 1.00 44.46  ? 101 ILE B CD1   1 
ATOM   3971 N  N     . PHE C 1 102 ? 112.495 111.078 127.784 1.00 40.42  ? 102 PHE B N     1 
ATOM   3972 C  CA    . PHE C 1 102 ? 112.441 109.624 127.674 1.00 46.99  ? 102 PHE B CA    1 
ATOM   3973 C  C     . PHE C 1 102 ? 111.089 109.175 127.139 1.00 47.42  ? 102 PHE B C     1 
ATOM   3974 O  O     . PHE C 1 102 ? 111.010 108.369 126.201 1.00 50.99  ? 102 PHE B O     1 
ATOM   3975 C  CB    . PHE C 1 102 ? 112.720 108.992 129.038 1.00 46.03  ? 102 PHE B CB    1 
ATOM   3976 C  CG    . PHE C 1 102 ? 112.656 107.492 129.044 1.00 46.53  ? 102 PHE B CG    1 
ATOM   3977 C  CD1   . PHE C 1 102 ? 113.180 106.752 128.001 1.00 49.38  ? 102 PHE B CD1   1 
ATOM   3978 C  CD2   . PHE C 1 102 ? 112.074 106.822 130.103 1.00 50.85  ? 102 PHE B CD2   1 
ATOM   3979 C  CE1   . PHE C 1 102 ? 113.120 105.373 128.015 1.00 53.50  ? 102 PHE B CE1   1 
ATOM   3980 C  CE2   . PHE C 1 102 ? 112.013 105.446 130.121 1.00 56.62  ? 102 PHE B CE2   1 
ATOM   3981 C  CZ    . PHE C 1 102 ? 112.536 104.721 129.076 1.00 55.78  ? 102 PHE B CZ    1 
ATOM   3982 N  N     . GLU C 1 103 ? 110.012 109.718 127.712 1.00 48.20  ? 103 GLU B N     1 
ATOM   3983 C  CA    . GLU C 1 103 ? 108.667 109.378 127.262 1.00 50.15  ? 103 GLU B CA    1 
ATOM   3984 C  C     . GLU C 1 103 ? 108.506 109.631 125.768 1.00 45.63  ? 103 GLU B C     1 
ATOM   3985 O  O     . GLU C 1 103 ? 108.128 108.732 125.007 1.00 50.41  ? 103 GLU B O     1 
ATOM   3986 C  CB    . GLU C 1 103 ? 107.646 110.202 128.043 1.00 54.72  ? 103 GLU B CB    1 
ATOM   3987 C  CG    . GLU C 1 103 ? 106.456 109.440 128.569 1.00 56.98  ? 103 GLU B CG    1 
ATOM   3988 C  CD    . GLU C 1 103 ? 105.850 110.120 129.778 1.00 69.04  ? 103 GLU B CD    1 
ATOM   3989 O  OE1   . GLU C 1 103 ? 104.974 110.991 129.595 1.00 79.90  ? 103 GLU B OE1   1 
ATOM   3990 O  OE2   . GLU C 1 103 ? 106.267 109.804 130.911 1.00 64.82  ? 103 GLU B OE2   1 
ATOM   3991 N  N     . ILE C 1 104 ? 108.824 110.848 125.328 1.00 42.25  ? 104 ILE B N     1 
ATOM   3992 C  CA    . ILE C 1 104 ? 108.533 111.236 123.952 1.00 43.29  ? 104 ILE B CA    1 
ATOM   3993 C  C     . ILE C 1 104 ? 109.446 110.507 122.973 1.00 45.42  ? 104 ILE B C     1 
ATOM   3994 O  O     . ILE C 1 104 ? 109.007 110.088 121.897 1.00 49.89  ? 104 ILE B O     1 
ATOM   3995 C  CB    . ILE C 1 104 ? 108.620 112.763 123.797 1.00 40.97  ? 104 ILE B CB    1 
ATOM   3996 C  CG1   . ILE C 1 104 ? 107.620 113.433 124.741 1.00 42.53  ? 104 ILE B CG1   1 
ATOM   3997 C  CG2   . ILE C 1 104 ? 108.356 113.167 122.358 1.00 42.05  ? 104 ILE B CG2   1 
ATOM   3998 C  CD1   . ILE C 1 104 ? 107.346 114.883 124.432 1.00 47.57  ? 104 ILE B CD1   1 
ATOM   3999 N  N     . VAL C 1 105 ? 110.723 110.338 123.319 1.00 44.86  ? 105 VAL B N     1 
ATOM   4000 C  CA    . VAL C 1 105 ? 111.648 109.656 122.420 1.00 40.35  ? 105 VAL B CA    1 
ATOM   4001 C  C     . VAL C 1 105 ? 111.267 108.191 122.260 1.00 44.96  ? 105 VAL B C     1 
ATOM   4002 O  O     . VAL C 1 105 ? 111.270 107.659 121.144 1.00 52.34  ? 105 VAL B O     1 
ATOM   4003 C  CB    . VAL C 1 105 ? 113.095 109.811 122.919 1.00 36.89  ? 105 VAL B CB    1 
ATOM   4004 C  CG1   . VAL C 1 105 ? 114.010 108.870 122.169 1.00 39.79  ? 105 VAL B CG1   1 
ATOM   4005 C  CG2   . VAL C 1 105 ? 113.556 111.242 122.746 1.00 36.85  ? 105 VAL B CG2   1 
ATOM   4006 N  N     . SER C 1 106 ? 110.934 107.508 123.361 1.00 42.98  ? 106 SER B N     1 
ATOM   4007 C  CA    . SER C 1 106 ? 110.514 106.116 123.238 1.00 44.84  ? 106 SER B CA    1 
ATOM   4008 C  C     . SER C 1 106 ? 109.207 106.003 122.465 1.00 51.41  ? 106 SER B C     1 
ATOM   4009 O  O     . SER C 1 106 ? 109.025 105.066 121.673 1.00 56.45  ? 106 SER B O     1 
ATOM   4010 C  CB    . SER C 1 106 ? 110.386 105.483 124.619 1.00 47.67  ? 106 SER B CB    1 
ATOM   4011 O  OG    . SER C 1 106 ? 111.653 105.378 125.241 1.00 57.86  ? 106 SER B OG    1 
ATOM   4012 N  N     . SER C 1 107 ? 108.290 106.954 122.667 1.00 51.75  ? 107 SER B N     1 
ATOM   4013 C  CA    . SER C 1 107 ? 107.050 106.947 121.900 1.00 49.06  ? 107 SER B CA    1 
ATOM   4014 C  C     . SER C 1 107 ? 107.322 107.125 120.413 1.00 53.67  ? 107 SER B C     1 
ATOM   4015 O  O     . SER C 1 107 ? 106.691 106.471 119.579 1.00 54.64  ? 107 SER B O     1 
ATOM   4016 C  CB    . SER C 1 107 ? 106.114 108.039 122.410 1.00 45.48  ? 107 SER B CB    1 
ATOM   4017 O  OG    . SER C 1 107 ? 105.874 107.886 123.797 1.00 48.18  ? 107 SER B OG    1 
ATOM   4018 N  N     . ALA C 1 108 ? 108.268 107.997 120.061 1.00 51.17  ? 108 ALA B N     1 
ATOM   4019 C  CA    . ALA C 1 108 ? 108.617 108.188 118.656 1.00 46.56  ? 108 ALA B CA    1 
ATOM   4020 C  C     . ALA C 1 108 ? 109.267 106.943 118.070 1.00 48.31  ? 108 ALA B C     1 
ATOM   4021 O  O     . ALA C 1 108 ? 108.996 106.576 116.920 1.00 59.41  ? 108 ALA B O     1 
ATOM   4022 C  CB    . ALA C 1 108 ? 109.544 109.392 118.504 1.00 50.80  ? 108 ALA B CB    1 
ATOM   4023 N  N     . VAL C 1 109 ? 110.137 106.286 118.839 1.00 44.01  ? 109 VAL B N     1 
ATOM   4024 C  CA    . VAL C 1 109 ? 110.789 105.073 118.352 1.00 47.91  ? 109 VAL B CA    1 
ATOM   4025 C  C     . VAL C 1 109 ? 109.752 103.997 118.060 1.00 58.81  ? 109 VAL B C     1 
ATOM   4026 O  O     . VAL C 1 109 ? 109.754 103.377 116.987 1.00 70.09  ? 109 VAL B O     1 
ATOM   4027 C  CB    . VAL C 1 109 ? 111.836 104.580 119.364 1.00 44.21  ? 109 VAL B CB    1 
ATOM   4028 C  CG1   . VAL C 1 109 ? 112.362 103.222 118.950 1.00 47.31  ? 109 VAL B CG1   1 
ATOM   4029 C  CG2   . VAL C 1 109 ? 112.969 105.574 119.479 1.00 51.04  ? 109 VAL B CG2   1 
ATOM   4030 N  N     . MET C 1 110 ? 108.831 103.774 118.999 1.00 56.79  ? 110 MET B N     1 
ATOM   4031 C  CA    . MET C 1 110 ? 107.826 102.749 118.754 1.00 57.37  ? 110 MET B CA    1 
ATOM   4032 C  C     . MET C 1 110 ? 106.782 103.189 117.732 1.00 62.28  ? 110 MET B C     1 
ATOM   4033 O  O     . MET C 1 110 ? 106.174 102.331 117.089 1.00 70.65  ? 110 MET B O     1 
ATOM   4034 C  CB    . MET C 1 110 ? 107.170 102.311 120.064 1.00 58.60  ? 110 MET B CB    1 
ATOM   4035 C  CG    . MET C 1 110 ? 108.179 102.049 121.171 1.00 62.87  ? 110 MET B CG    1 
ATOM   4036 S  SD    . MET C 1 110 ? 107.508 101.189 122.603 1.00 80.75  ? 110 MET B SD    1 
ATOM   4037 C  CE    . MET C 1 110 ? 105.924 101.985 122.770 1.00 54.71  ? 110 MET B CE    1 
ATOM   4038 N  N     . TRP C 1 111 ? 106.590 104.494 117.525 1.00 56.43  ? 111 TRP B N     1 
ATOM   4039 C  CA    . TRP C 1 111 ? 105.750 104.942 116.418 1.00 57.61  ? 111 TRP B CA    1 
ATOM   4040 C  C     . TRP C 1 111 ? 106.394 104.627 115.076 1.00 61.30  ? 111 TRP B C     1 
ATOM   4041 O  O     . TRP C 1 111 ? 105.708 104.222 114.134 1.00 68.80  ? 111 TRP B O     1 
ATOM   4042 C  CB    . TRP C 1 111 ? 105.466 106.439 116.538 1.00 59.37  ? 111 TRP B CB    1 
ATOM   4043 C  CG    . TRP C 1 111 ? 104.803 107.038 115.326 1.00 61.79  ? 111 TRP B CG    1 
ATOM   4044 C  CD1   . TRP C 1 111 ? 105.402 107.389 114.150 1.00 61.81  ? 111 TRP B CD1   1 
ATOM   4045 C  CD2   . TRP C 1 111 ? 103.414 107.356 115.175 1.00 65.74  ? 111 TRP B CD2   1 
ATOM   4046 N  NE1   . TRP C 1 111 ? 104.476 107.904 113.280 1.00 66.26  ? 111 TRP B NE1   1 
ATOM   4047 C  CE2   . TRP C 1 111 ? 103.247 107.896 113.885 1.00 68.18  ? 111 TRP B CE2   1 
ATOM   4048 C  CE3   . TRP C 1 111 ? 102.298 107.241 116.006 1.00 70.45  ? 111 TRP B CE3   1 
ATOM   4049 C  CZ2   . TRP C 1 111 ? 102.010 108.316 113.407 1.00 74.50  ? 111 TRP B CZ2   1 
ATOM   4050 C  CZ3   . TRP C 1 111 ? 101.070 107.659 115.529 1.00 73.84  ? 111 TRP B CZ3   1 
ATOM   4051 C  CH2   . TRP C 1 111 ? 100.936 108.190 114.243 1.00 75.12  ? 111 TRP B CH2   1 
ATOM   4052 N  N     . ASN C 1 112 ? 107.707 104.830 114.961 1.00 59.03  ? 112 ASN B N     1 
ATOM   4053 C  CA    . ASN C 1 112 ? 108.401 104.432 113.740 1.00 61.13  ? 112 ASN B CA    1 
ATOM   4054 C  C     . ASN C 1 112 ? 108.308 102.926 113.531 1.00 67.77  ? 112 ASN B C     1 
ATOM   4055 O  O     . ASN C 1 112 ? 108.109 102.455 112.403 1.00 77.69  ? 112 ASN B O     1 
ATOM   4056 C  CB    . ASN C 1 112 ? 109.860 104.881 113.790 1.00 61.30  ? 112 ASN B CB    1 
ATOM   4057 C  CG    . ASN C 1 112 ? 110.074 106.234 113.148 1.00 66.63  ? 112 ASN B CG    1 
ATOM   4058 O  OD1   . ASN C 1 112 ? 109.282 106.669 112.316 1.00 73.50  ? 112 ASN B OD1   1 
ATOM   4059 N  ND2   . ASN C 1 112 ? 111.152 106.905 113.527 1.00 61.54  ? 112 ASN B ND2   1 
ATOM   4060 N  N     . CYS C 1 113 ? 108.445 102.155 114.613 1.00 64.95  ? 113 CYS B N     1 
ATOM   4061 C  CA    . CYS C 1 113 ? 108.283 100.707 114.510 1.00 70.57  ? 113 CYS B CA    1 
ATOM   4062 C  C     . CYS C 1 113 ? 106.883 100.342 114.030 1.00 76.15  ? 113 CYS B C     1 
ATOM   4063 O  O     . CYS C 1 113 ? 106.719 99.454  113.184 1.00 78.25  ? 113 CYS B O     1 
ATOM   4064 C  CB    . CYS C 1 113 ? 108.569 100.048 115.857 1.00 67.25  ? 113 CYS B CB    1 
ATOM   4065 S  SG    . CYS C 1 113 ? 110.221 100.341 116.504 1.00 81.79  ? 113 CYS B SG    1 
ATOM   4066 N  N     . ALA C 1 114 ? 105.862 101.017 114.561 1.00 72.82  ? 114 ALA B N     1 
ATOM   4067 C  CA    . ALA C 1 114 ? 104.488 100.756 114.145 1.00 71.03  ? 114 ALA B CA    1 
ATOM   4068 C  C     . ALA C 1 114 ? 104.272 101.122 112.684 1.00 78.43  ? 114 ALA B C     1 
ATOM   4069 O  O     . ALA C 1 114 ? 103.554 100.423 111.962 1.00 88.70  ? 114 ALA B O     1 
ATOM   4070 C  CB    . ALA C 1 114 ? 103.518 101.525 115.039 1.00 68.11  ? 114 ALA B CB    1 
ATOM   4071 N  N     . ALA C 1 115 ? 104.867 102.228 112.234 1.00 73.78  ? 115 ALA B N     1 
ATOM   4072 C  CA    . ALA C 1 115 ? 104.748 102.613 110.832 1.00 77.18  ? 115 ALA B CA    1 
ATOM   4073 C  C     . ALA C 1 115 ? 105.382 101.572 109.921 1.00 80.32  ? 115 ALA B C     1 
ATOM   4074 O  O     . ALA C 1 115 ? 104.811 101.211 108.884 1.00 86.41  ? 115 ALA B O     1 
ATOM   4075 C  CB    . ALA C 1 115 ? 105.383 103.984 110.608 1.00 80.10  ? 115 ALA B CB    1 
ATOM   4076 N  N     . ARG C 1 116 ? 106.560 101.069 110.296 1.00 75.70  ? 116 ARG B N     1 
ATOM   4077 C  CA    . ARG C 1 116 ? 107.193 100.017 109.504 1.00 74.77  ? 116 ARG B CA    1 
ATOM   4078 C  C     . ARG C 1 116 ? 106.348 98.747  109.496 1.00 80.92  ? 116 ARG B C     1 
ATOM   4079 O  O     . ARG C 1 116 ? 106.209 98.087  108.458 1.00 88.01  ? 116 ARG B O     1 
ATOM   4080 C  CB    . ARG C 1 116 ? 108.590 99.725  110.042 1.00 79.73  ? 116 ARG B CB    1 
ATOM   4081 C  CG    . ARG C 1 116 ? 109.341 98.673  109.255 1.00 86.65  ? 116 ARG B CG    1 
ATOM   4082 C  CD    . ARG C 1 116 ? 110.824 98.722  109.559 1.00 88.86  ? 116 ARG B CD    1 
ATOM   4083 N  NE    . ARG C 1 116 ? 111.379 100.051 109.341 1.00 83.21  ? 116 ARG B NE    1 
ATOM   4084 C  CZ    . ARG C 1 116 ? 112.675 100.326 109.334 1.00 81.03  ? 116 ARG B CZ    1 
ATOM   4085 N  NH1   . ARG C 1 116 ? 113.580 99.383  109.534 1.00 82.55  ? 116 ARG B NH1   1 
ATOM   4086 N  NH2   . ARG C 1 116 ? 113.071 101.577 109.121 1.00 80.13  ? 116 ARG B NH2   1 
ATOM   4087 N  N     . TRP C 1 117 ? 105.776 98.392  110.648 1.00 80.20  ? 117 TRP B N     1 
ATOM   4088 C  CA    . TRP C 1 117 ? 104.926 97.209  110.732 1.00 79.03  ? 117 TRP B CA    1 
ATOM   4089 C  C     . TRP C 1 117 ? 103.695 97.347  109.846 1.00 81.26  ? 117 TRP B C     1 
ATOM   4090 O  O     . TRP C 1 117 ? 103.313 96.402  109.148 1.00 84.48  ? 117 TRP B O     1 
ATOM   4091 C  CB    . TRP C 1 117 ? 104.524 96.978  112.187 1.00 78.60  ? 117 TRP B CB    1 
ATOM   4092 C  CG    . TRP C 1 117 ? 103.593 95.836  112.413 1.00 80.16  ? 117 TRP B CG    1 
ATOM   4093 C  CD1   . TRP C 1 117 ? 102.231 95.877  112.415 1.00 83.14  ? 117 TRP B CD1   1 
ATOM   4094 C  CD2   . TRP C 1 117 ? 103.954 94.484  112.707 1.00 82.78  ? 117 TRP B CD2   1 
ATOM   4095 N  NE1   . TRP C 1 117 ? 101.721 94.630  112.677 1.00 86.70  ? 117 TRP B NE1   1 
ATOM   4096 C  CE2   . TRP C 1 117 ? 102.760 93.757  112.861 1.00 87.05  ? 117 TRP B CE2   1 
ATOM   4097 C  CE3   . TRP C 1 117 ? 105.173 93.815  112.848 1.00 84.82  ? 117 TRP B CE3   1 
ATOM   4098 C  CZ2   . TRP C 1 117 ? 102.747 92.396  113.150 1.00 90.44  ? 117 TRP B CZ2   1 
ATOM   4099 C  CZ3   . TRP C 1 117 ? 105.158 92.464  113.134 1.00 87.49  ? 117 TRP B CZ3   1 
ATOM   4100 C  CH2   . TRP C 1 117 ? 103.954 91.768  113.280 1.00 89.54  ? 117 TRP B CH2   1 
ATOM   4101 N  N     . ASN C 1 118 ? 103.059 98.521  109.861 1.00 82.27  ? 118 ASN B N     1 
ATOM   4102 C  CA    . ASN C 1 118 ? 101.900 98.753  109.004 1.00 84.65  ? 118 ASN B CA    1 
ATOM   4103 C  C     . ASN C 1 118 ? 102.282 98.700  107.531 1.00 91.49  ? 118 ASN B C     1 
ATOM   4104 O  O     . ASN C 1 118 ? 101.544 98.140  106.709 1.00 98.61  ? 118 ASN B O     1 
ATOM   4105 C  CB    . ASN C 1 118 ? 101.255 100.097 109.341 1.00 79.17  ? 118 ASN B CB    1 
ATOM   4106 C  CG    . ASN C 1 118 ? 100.777 100.172 110.776 1.00 80.17  ? 118 ASN B CG    1 
ATOM   4107 O  OD1   . ASN C 1 118 ? 100.555 99.151  111.423 1.00 79.63  ? 118 ASN B OD1   1 
ATOM   4108 N  ND2   . ASN C 1 118 ? 100.616 101.387 111.281 1.00 83.88  ? 118 ASN B ND2   1 
ATOM   4109 N  N     . SER C 1 119 ? 103.428 99.286  107.175 1.00 90.62  ? 119 SER B N     1 
ATOM   4110 C  CA    . SER C 1 119 ? 103.883 99.228  105.791 1.00 89.10  ? 119 SER B CA    1 
ATOM   4111 C  C     . SER C 1 119 ? 104.101 97.788  105.349 1.00 90.13  ? 119 SER B C     1 
ATOM   4112 O  O     . SER C 1 119 ? 103.770 97.422  104.215 1.00 97.98  ? 119 SER B O     1 
ATOM   4113 C  CB    . SER C 1 119 ? 105.164 100.042 105.624 1.00 89.56  ? 119 SER B CB    1 
ATOM   4114 O  OG    . SER C 1 119 ? 105.993 99.485  104.620 1.00 93.43  ? 119 SER B OG    1 
ATOM   4115 N  N     . LEU C 1 120 ? 104.662 96.957  106.230 1.00 88.37  ? 120 LEU B N     1 
ATOM   4116 C  CA    . LEU C 1 120 ? 104.809 95.541  105.905 1.00 92.45  ? 120 LEU B CA    1 
ATOM   4117 C  C     . LEU C 1 120 ? 103.451 94.864  105.757 1.00 96.46  ? 120 LEU B C     1 
ATOM   4118 O  O     . LEU C 1 120 ? 103.247 94.058  104.842 1.00 101.23 ? 120 LEU B O     1 
ATOM   4119 C  CB    . LEU C 1 120 ? 105.641 94.834  106.973 1.00 94.56  ? 120 LEU B CB    1 
ATOM   4120 C  CG    . LEU C 1 120 ? 105.528 93.308  106.998 1.00 90.82  ? 120 LEU B CG    1 
ATOM   4121 C  CD1   . LEU C 1 120 ? 106.168 92.699  105.761 1.00 90.80  ? 120 LEU B CD1   1 
ATOM   4122 C  CD2   . LEU C 1 120 ? 106.150 92.738  108.260 1.00 93.90  ? 120 LEU B CD2   1 
ATOM   4123 N  N     . MET C 1 121 ? 102.511 95.178  106.652 1.00 95.16  ? 121 MET B N     1 
ATOM   4124 C  CA    . MET C 1 121 ? 101.221 94.492  106.644 1.00 98.08  ? 121 MET B CA    1 
ATOM   4125 C  C     . MET C 1 121 ? 100.413 94.819  105.395 1.00 101.25 ? 121 MET B C     1 
ATOM   4126 O  O     . MET C 1 121 ? 99.749  93.939  104.835 1.00 105.22 ? 121 MET B O     1 
ATOM   4127 C  CB    . MET C 1 121 ? 100.429 94.839  107.903 1.00 93.22  ? 121 MET B CB    1 
ATOM   4128 C  CG    . MET C 1 121 ? 100.930 94.124  109.140 1.00 92.88  ? 121 MET B CG    1 
ATOM   4129 S  SD    . MET C 1 121 ? 101.339 92.413  108.759 1.00 101.58 ? 121 MET B SD    1 
ATOM   4130 C  CE    . MET C 1 121 ? 100.970 91.612  110.313 1.00 99.23  ? 121 MET B CE    1 
ATOM   4131 N  N     . VAL C 1 122 ? 100.441 96.077  104.951 1.00 99.61  ? 122 VAL B N     1 
ATOM   4132 C  CA    . VAL C 1 122 ? 99.694  96.446  103.750 1.00 101.51 ? 122 VAL B CA    1 
ATOM   4133 C  C     . VAL C 1 122 ? 100.229 95.698  102.535 1.00 103.10 ? 122 VAL B C     1 
ATOM   4134 O  O     . VAL C 1 122 ? 99.458  95.190  101.711 1.00 107.36 ? 122 VAL B O     1 
ATOM   4135 C  CB    . VAL C 1 122 ? 99.729  97.971  103.543 1.00 101.94 ? 122 VAL B CB    1 
ATOM   4136 C  CG1   . VAL C 1 122 ? 99.358  98.325  102.114 1.00 101.21 ? 122 VAL B CG1   1 
ATOM   4137 C  CG2   . VAL C 1 122 ? 98.778  98.641  104.508 1.00 99.30  ? 122 VAL B CG2   1 
ATOM   4138 N  N     . GLY C 1 123 ? 101.549 95.602  102.412 1.00 99.71  ? 123 GLY B N     1 
ATOM   4139 C  CA    . GLY C 1 123 ? 102.144 94.903  101.290 1.00 96.97  ? 123 GLY B CA    1 
ATOM   4140 C  C     . GLY C 1 123 ? 103.208 95.712  100.581 1.00 102.71 ? 123 GLY B C     1 
ATOM   4141 O  O     . GLY C 1 123 ? 103.602 95.384  99.458  1.00 109.59 ? 123 GLY B O     1 
ATOM   4142 N  N     . GLU C 1 124 ? 103.683 96.774  101.229 1.00 102.87 ? 124 GLU B N     1 
ATOM   4143 C  CA    . GLU C 1 124 ? 104.704 97.643  100.664 1.00 102.75 ? 124 GLU B CA    1 
ATOM   4144 C  C     . GLU C 1 124 ? 106.118 97.183  100.998 1.00 102.82 ? 124 GLU B C     1 
ATOM   4145 O  O     . GLU C 1 124 ? 107.044 98.003  100.998 1.00 104.90 ? 124 GLU B O     1 
ATOM   4146 C  CB    . GLU C 1 124 ? 104.492 99.081  101.139 1.00 102.02 ? 124 GLU B CB    1 
ATOM   4147 C  CG    . GLU C 1 124 ? 103.033 99.479  101.267 1.00 103.79 ? 124 GLU B CG    1 
ATOM   4148 C  CD    . GLU C 1 124 ? 102.842 100.982 101.299 1.00 116.32 ? 124 GLU B CD    1 
ATOM   4149 O  OE1   . GLU C 1 124 ? 103.856 101.711 101.315 1.00 119.92 ? 124 GLU B OE1   1 
ATOM   4150 O  OE2   . GLU C 1 124 ? 101.678 101.435 101.305 1.00 123.60 ? 124 GLU B OE2   1 
ATOM   4151 N  N     . GLY C 1 125 ? 106.303 95.899  101.284 1.00 99.81  ? 125 GLY B N     1 
ATOM   4152 C  CA    . GLY C 1 125 ? 107.619 95.373  101.566 1.00 102.05 ? 125 GLY B CA    1 
ATOM   4153 C  C     . GLY C 1 125 ? 108.078 95.660  102.983 1.00 103.63 ? 125 GLY B C     1 
ATOM   4154 O  O     . GLY C 1 125 ? 107.327 96.126  103.844 1.00 98.86  ? 125 GLY B O     1 
ATOM   4155 N  N     . TRP C 1 126 ? 109.355 95.368  103.216 1.00 105.48 ? 126 TRP B N     1 
ATOM   4156 C  CA    . TRP C 1 126 ? 109.984 95.540  104.522 1.00 98.14  ? 126 TRP B CA    1 
ATOM   4157 C  C     . TRP C 1 126 ? 111.249 96.366  104.336 1.00 94.62  ? 126 TRP B C     1 
ATOM   4158 C  CB    . TRP C 1 126 ? 110.302 94.186  105.156 1.00 101.40 ? 126 TRP B CB    1 
ATOM   4159 C  CG    . TRP C 1 126 ? 110.998 94.279  106.475 1.00 103.46 ? 126 TRP B CG    1 
ATOM   4160 C  CD1   . TRP C 1 126 ? 112.324 94.075  106.716 1.00 103.41 ? 126 TRP B CD1   1 
ATOM   4161 C  CD2   . TRP C 1 126 ? 110.403 94.589  107.740 1.00 101.07 ? 126 TRP B CD2   1 
ATOM   4162 N  NE1   . TRP C 1 126 ? 112.593 94.244  108.052 1.00 103.93 ? 126 TRP B NE1   1 
ATOM   4163 C  CE2   . TRP C 1 126 ? 111.430 94.560  108.702 1.00 100.20 ? 126 TRP B CE2   1 
ATOM   4164 C  CE3   . TRP C 1 126 ? 109.102 94.891  108.151 1.00 96.31  ? 126 TRP B CE3   1 
ATOM   4165 C  CZ2   . TRP C 1 126 ? 111.197 94.820  110.049 1.00 93.94  ? 126 TRP B CZ2   1 
ATOM   4166 C  CZ3   . TRP C 1 126 ? 108.874 95.149  109.488 1.00 91.87  ? 126 TRP B CZ3   1 
ATOM   4167 C  CH2   . TRP C 1 126 ? 109.915 95.113  110.421 1.00 91.53  ? 126 TRP B CH2   1 
ATOM   4168 N  N     . ARG C 1 127 ? 111.198 97.634  104.738 1.00 93.35  ? 127 ARG B N     1 
ATOM   4169 C  CA    . ARG C 1 127 ? 112.359 98.500  104.596 1.00 95.12  ? 127 ARG B CA    1 
ATOM   4170 C  C     . ARG C 1 127 ? 113.556 97.896  105.315 1.00 99.75  ? 127 ARG B C     1 
ATOM   4171 O  O     . ARG C 1 127 ? 113.445 97.409  106.443 1.00 100.94 ? 127 ARG B O     1 
ATOM   4172 C  CB    . ARG C 1 127 ? 112.054 99.891  105.150 1.00 88.90  ? 127 ARG B CB    1 
ATOM   4173 C  CG    . ARG C 1 127 ? 110.792 100.512 104.583 1.00 87.25  ? 127 ARG B CG    1 
ATOM   4174 C  CD    . ARG C 1 127 ? 110.305 101.659 105.446 1.00 89.31  ? 127 ARG B CD    1 
ATOM   4175 N  NE    . ARG C 1 127 ? 108.853 101.776 105.424 1.00 90.50  ? 127 ARG B NE    1 
ATOM   4176 C  CZ    . ARG C 1 127 ? 108.196 102.927 105.415 1.00 93.48  ? 127 ARG B CZ    1 
ATOM   4177 N  NH1   . ARG C 1 127 ? 108.834 104.086 105.421 1.00 91.95  ? 127 ARG B NH1   1 
ATOM   4178 N  NH2   . ARG C 1 127 ? 106.867 102.916 105.399 1.00 96.56  ? 127 ARG B NH2   1 
ATOM   4179 N  N     . SER C 1 128 ? 114.713 97.928  104.652 1.00 101.07 ? 128 SER B N     1 
ATOM   4180 C  CA    . SER C 1 128 ? 115.915 97.286  105.168 1.00 104.39 ? 128 SER B CA    1 
ATOM   4181 C  C     . SER C 1 128 ? 117.072 98.263  105.340 1.00 103.32 ? 128 SER B C     1 
ATOM   4182 O  O     . SER C 1 128 ? 118.223 97.832  105.457 1.00 107.12 ? 128 SER B O     1 
ATOM   4183 C  CB    . SER C 1 128 ? 116.333 96.129  104.259 1.00 108.94 ? 128 SER B CB    1 
ATOM   4184 O  OG    . SER C 1 128 ? 117.263 95.281  104.908 1.00 116.87 ? 128 SER B OG    1 
ATOM   4185 N  N     . GLN C 1 129 ? 116.802 99.569  105.347 1.00 101.38 ? 129 GLN B N     1 
ATOM   4186 C  CA    . GLN C 1 129 ? 117.878 100.524 105.606 1.00 108.24 ? 129 GLN B CA    1 
ATOM   4187 C  C     . GLN C 1 129 ? 118.477 100.333 106.993 1.00 111.64 ? 129 GLN B C     1 
ATOM   4188 O  O     . GLN C 1 129 ? 119.714 100.267 107.100 1.00 115.79 ? 129 GLN B O     1 
ATOM   4189 C  CB    . GLN C 1 129 ? 117.375 101.955 105.379 1.00 112.56 ? 129 GLN B CB    1 
ATOM   4190 C  CG    . GLN C 1 129 ? 118.414 103.028 105.657 1.00 116.69 ? 129 GLN B CG    1 
ATOM   4191 C  CD    . GLN C 1 129 ? 119.699 102.809 104.884 1.00 123.61 ? 129 GLN B CD    1 
ATOM   4192 O  OE1   . GLN C 1 129 ? 120.700 102.352 105.436 1.00 123.55 ? 129 GLN B OE1   1 
ATOM   4193 N  NE2   . GLN C 1 129 ? 119.678 103.135 103.596 1.00 125.05 ? 129 GLN B NE2   1 
ATOM   4194 N  N     . PRO C 1 130 ? 117.700 100.231 108.076 1.00 107.45 ? 130 PRO B N     1 
ATOM   4195 C  CA    . PRO C 1 130 ? 118.254 99.680  109.317 1.00 102.40 ? 130 PRO B CA    1 
ATOM   4196 C  C     . PRO C 1 130 ? 118.075 98.171  109.356 1.00 98.65  ? 130 PRO B C     1 
ATOM   4197 O  O     . PRO C 1 130 ? 117.003 97.635  109.066 1.00 97.32  ? 130 PRO B O     1 
ATOM   4198 C  CB    . PRO C 1 130 ? 117.425 100.369 110.413 1.00 89.36  ? 130 PRO B CB    1 
ATOM   4199 C  CG    . PRO C 1 130 ? 116.429 101.258 109.694 1.00 90.86  ? 130 PRO B CG    1 
ATOM   4200 C  CD    . PRO C 1 130 ? 116.342 100.747 108.301 1.00 100.36 ? 130 PRO B CD    1 
ATOM   4201 N  N     . ARG C 1 131 ? 119.149 97.475  109.721 1.00 94.91  ? 131 ARG B N     1 
ATOM   4202 C  CA    . ARG C 1 131 ? 119.139 96.018  109.693 1.00 96.26  ? 131 ARG B CA    1 
ATOM   4203 C  C     . ARG C 1 131 ? 118.275 95.457  110.815 1.00 98.01  ? 131 ARG B C     1 
ATOM   4204 O  O     . ARG C 1 131 ? 118.746 95.278  111.942 1.00 103.40 ? 131 ARG B O     1 
ATOM   4205 C  CB    . ARG C 1 131 ? 120.568 95.476  109.791 1.00 101.20 ? 131 ARG B CB    1 
ATOM   4206 C  CG    . ARG C 1 131 ? 120.684 93.955  109.758 1.00 102.92 ? 131 ARG B CG    1 
ATOM   4207 C  CD    . ARG C 1 131 ? 119.916 93.348  108.595 1.00 108.50 ? 131 ARG B CD    1 
ATOM   4208 N  NE    . ARG C 1 131 ? 119.681 91.922  108.790 1.00 111.63 ? 131 ARG B NE    1 
ATOM   4209 C  CZ    . ARG C 1 131 ? 119.082 91.132  107.909 1.00 107.42 ? 131 ARG B CZ    1 
ATOM   4210 N  NH1   . ARG C 1 131 ? 118.635 91.599  106.755 1.00 104.87 ? 131 ARG B NH1   1 
ATOM   4211 N  NH2   . ARG C 1 131 ? 118.927 89.843  108.195 1.00 95.17  ? 131 ARG B NH2   1 
ATOM   4212 N  N     . TYR C 1 132 ? 117.008 95.183  110.514 1.00 90.55  ? 132 TYR B N     1 
ATOM   4213 C  CA    . TYR C 1 132 ? 116.083 94.567  111.453 1.00 89.02  ? 132 TYR B CA    1 
ATOM   4214 C  C     . TYR C 1 132 ? 115.508 93.297  110.842 1.00 92.85  ? 132 TYR B C     1 
ATOM   4215 O  O     . TYR C 1 132 ? 115.307 93.210  109.627 1.00 98.98  ? 132 TYR B O     1 
ATOM   4216 C  CB    . TYR C 1 132 ? 114.939 95.518  111.831 1.00 93.18  ? 132 TYR B CB    1 
ATOM   4217 C  CG    . TYR C 1 132 ? 115.327 96.603  112.809 1.00 91.46  ? 132 TYR B CG    1 
ATOM   4218 C  CD1   . TYR C 1 132 ? 116.401 96.439  113.670 1.00 89.99  ? 132 TYR B CD1   1 
ATOM   4219 C  CD2   . TYR C 1 132 ? 114.615 97.792  112.872 1.00 82.59  ? 132 TYR B CD2   1 
ATOM   4220 C  CE1   . TYR C 1 132 ? 116.756 97.428  114.561 1.00 82.99  ? 132 TYR B CE1   1 
ATOM   4221 C  CE2   . TYR C 1 132 ? 114.964 98.786  113.760 1.00 77.00  ? 132 TYR B CE2   1 
ATOM   4222 C  CZ    . TYR C 1 132 ? 116.035 98.598  114.602 1.00 80.54  ? 132 TYR B CZ    1 
ATOM   4223 O  OH    . TYR C 1 132 ? 116.387 99.586  115.490 1.00 83.14  ? 132 TYR B OH    1 
ATOM   4224 N  N     . SER C 1 133 ? 115.248 92.311  111.695 1.00 93.02  ? 133 SER B N     1 
ATOM   4225 C  CA    . SER C 1 133 ? 114.704 91.045  111.227 1.00 99.21  ? 133 SER B CA    1 
ATOM   4226 C  C     . SER C 1 133 ? 113.281 91.226  110.715 1.00 98.10  ? 133 SER B C     1 
ATOM   4227 O  O     . SER C 1 133 ? 112.477 91.951  111.306 1.00 95.87  ? 133 SER B O     1 
ATOM   4228 C  CB    . SER C 1 133 ? 114.730 90.009  112.350 1.00 96.84  ? 133 SER B CB    1 
ATOM   4229 O  OG    . SER C 1 133 ? 113.804 90.342  113.369 1.00 96.30  ? 133 SER B OG    1 
ATOM   4230 N  N     . ARG C 1 134 ? 112.975 90.563  109.608 1.00 99.75  ? 134 ARG B N     1 
ATOM   4231 C  CA    . ARG C 1 134 ? 111.632 90.619  109.046 1.00 101.25 ? 134 ARG B CA    1 
ATOM   4232 C  C     . ARG C 1 134 ? 110.695 89.725  109.851 1.00 102.47 ? 134 ARG B C     1 
ATOM   4233 O  O     . ARG C 1 134 ? 110.988 88.540  110.036 1.00 100.13 ? 134 ARG B O     1 
ATOM   4234 C  CB    . ARG C 1 134 ? 111.642 90.184  107.585 1.00 104.01 ? 134 ARG B CB    1 
ATOM   4235 C  CG    . ARG C 1 134 ? 110.278 90.221  106.921 1.00 105.31 ? 134 ARG B CG    1 
ATOM   4236 C  CD    . ARG C 1 134 ? 110.234 89.309  105.710 1.00 104.91 ? 134 ARG B CD    1 
ATOM   4237 N  NE    . ARG C 1 134 ? 110.606 90.012  104.489 1.00 111.58 ? 134 ARG B NE    1 
ATOM   4238 C  CZ    . ARG C 1 134 ? 109.739 90.540  103.637 1.00 114.01 ? 134 ARG B CZ    1 
ATOM   4239 N  NH1   . ARG C 1 134 ? 108.435 90.466  103.843 1.00 110.86 ? 134 ARG B NH1   1 
ATOM   4240 N  NH2   . ARG C 1 134 ? 110.193 91.160  102.551 1.00 116.16 ? 134 ARG B NH2   1 
ATOM   4241 N  N     . PRO C 1 135 ? 109.579 90.253  110.351 1.00 103.02 ? 135 PRO B N     1 
ATOM   4242 C  CA    . PRO C 1 135 ? 108.660 89.424  111.139 1.00 102.24 ? 135 PRO B CA    1 
ATOM   4243 C  C     . PRO C 1 135 ? 108.095 88.277  110.315 1.00 103.70 ? 135 PRO B C     1 
ATOM   4244 O  O     . PRO C 1 135 ? 107.817 88.419  109.123 1.00 100.93 ? 135 PRO B O     1 
ATOM   4245 C  CB    . PRO C 1 135 ? 107.562 90.409  111.559 1.00 98.38  ? 135 PRO B CB    1 
ATOM   4246 C  CG    . PRO C 1 135 ? 108.164 91.767  111.381 1.00 100.00 ? 135 PRO B CG    1 
ATOM   4247 C  CD    . PRO C 1 135 ? 109.114 91.644  110.237 1.00 101.29 ? 135 PRO B CD    1 
ATOM   4248 N  N     . THR C 1 136 ? 107.927 87.131  110.968 1.00 108.27 ? 136 THR B N     1 
ATOM   4249 C  CA    . THR C 1 136 ? 107.407 85.927  110.320 1.00 107.92 ? 136 THR B CA    1 
ATOM   4250 C  C     . THR C 1 136 ? 105.894 85.809  110.477 1.00 107.71 ? 136 THR B C     1 
ATOM   4251 O  O     . THR C 1 136 ? 105.371 84.800  110.947 1.00 106.41 ? 136 THR B O     1 
ATOM   4252 C  CB    . THR C 1 136 ? 108.114 84.695  110.873 1.00 108.63 ? 136 THR B CB    1 
ATOM   4253 O  OG1   . THR C 1 136 ? 107.390 83.517  110.497 1.00 114.71 ? 136 THR B OG1   1 
ATOM   4254 C  CG2   . THR C 1 136 ? 108.212 84.770  112.391 1.00 102.99 ? 136 THR B CG2   1 
ATOM   4255 N  N     . LEU C 1 137 ? 105.175 86.853  110.076 1.00 107.74 ? 137 LEU B N     1 
ATOM   4256 C  CA    . LEU C 1 137 ? 103.722 86.876  110.142 1.00 109.42 ? 137 LEU B CA    1 
ATOM   4257 C  C     . LEU C 1 137 ? 103.146 87.162  108.763 1.00 111.35 ? 137 LEU B C     1 
ATOM   4258 O  O     . LEU C 1 137 ? 103.725 87.915  107.973 1.00 111.13 ? 137 LEU B O     1 
ATOM   4259 C  CB    . LEU C 1 137 ? 103.225 87.924  111.143 1.00 107.44 ? 137 LEU B CB    1 
ATOM   4260 C  CG    . LEU C 1 137 ? 102.002 87.520  111.968 1.00 109.38 ? 137 LEU B CG    1 
ATOM   4261 C  CD1   . LEU C 1 137 ? 102.381 86.488  113.016 1.00 109.48 ? 137 LEU B CD1   1 
ATOM   4262 C  CD2   . LEU C 1 137 ? 101.362 88.735  112.616 1.00 106.65 ? 137 LEU B CD2   1 
ATOM   4263 N  N     . SER C 1 138 ? 102.003 86.551  108.480 1.00 112.16 ? 138 SER B N     1 
ATOM   4264 C  CA    . SER C 1 138 ? 101.361 86.739  107.186 1.00 112.74 ? 138 SER B CA    1 
ATOM   4265 C  C     . SER C 1 138 ? 100.834 88.165  107.071 1.00 111.39 ? 138 SER B C     1 
ATOM   4266 O  O     . SER C 1 138 ? 100.067 88.607  107.933 1.00 111.94 ? 138 SER B O     1 
ATOM   4267 C  CB    . SER C 1 138 ? 100.223 85.738  107.006 1.00 112.13 ? 138 SER B CB    1 
ATOM   4268 O  OG    . SER C 1 138 ? 99.201  85.952  107.963 1.00 119.34 ? 138 SER B OG    1 
ATOM   4269 N  N     . PRO C 1 139 ? 101.226 88.912  106.040 1.00 109.43 ? 139 PRO B N     1 
ATOM   4270 C  CA    . PRO C 1 139 ? 100.745 90.292  105.905 1.00 106.77 ? 139 PRO B CA    1 
ATOM   4271 C  C     . PRO C 1 139 ? 99.230  90.350  105.779 1.00 106.49 ? 139 PRO B C     1 
ATOM   4272 O  O     . PRO C 1 139 ? 98.606  89.492  105.151 1.00 111.10 ? 139 PRO B O     1 
ATOM   4273 C  CB    . PRO C 1 139 ? 101.435 90.784  104.628 1.00 106.76 ? 139 PRO B CB    1 
ATOM   4274 C  CG    . PRO C 1 139 ? 102.639 89.914  104.489 1.00 110.64 ? 139 PRO B CG    1 
ATOM   4275 C  CD    . PRO C 1 139 ? 102.231 88.572  105.019 1.00 111.10 ? 139 PRO B CD    1 
ATOM   4276 N  N     . SER C 1 140 ? 98.643  91.379  106.386 1.00 102.23 ? 140 SER B N     1 
ATOM   4277 C  CA    . SER C 1 140 ? 97.202  91.587  106.359 1.00 100.69 ? 140 SER B CA    1 
ATOM   4278 C  C     . SER C 1 140 ? 96.875  93.019  106.761 1.00 104.02 ? 140 SER B C     1 
ATOM   4279 O  O     . SER C 1 140 ? 97.391  93.511  107.772 1.00 108.03 ? 140 SER B O     1 
ATOM   4280 C  CB    . SER C 1 140 ? 96.495  90.602  107.288 1.00 105.40 ? 140 SER B CB    1 
ATOM   4281 O  OG    . SER C 1 140 ? 95.175  91.034  107.566 1.00 108.84 ? 140 SER B OG    1 
ATOM   4282 N  N     . PRO C 1 141 ? 96.030  93.718  106.001 1.00 105.46 ? 141 PRO B N     1 
ATOM   4283 C  CA    . PRO C 1 141 ? 95.687  95.102  106.370 1.00 106.73 ? 141 PRO B CA    1 
ATOM   4284 C  C     . PRO C 1 141 ? 94.968  95.218  107.701 1.00 104.96 ? 141 PRO B C     1 
ATOM   4285 O  O     . PRO C 1 141 ? 94.972  96.304  108.294 1.00 104.51 ? 141 PRO B O     1 
ATOM   4286 C  CB    . PRO C 1 141 ? 94.794  95.574  105.214 1.00 105.18 ? 141 PRO B CB    1 
ATOM   4287 C  CG    . PRO C 1 141 ? 94.988  94.591  104.115 1.00 107.93 ? 141 PRO B CG    1 
ATOM   4288 C  CD    . PRO C 1 141 ? 95.427  93.302  104.725 1.00 104.76 ? 141 PRO B CD    1 
ATOM   4289 N  N     . ARG C 1 142 ? 94.353  94.144  108.192 1.00 107.40 ? 142 ARG B N     1 
ATOM   4290 C  CA    . ARG C 1 142 ? 93.593  94.190  109.433 1.00 108.78 ? 142 ARG B CA    1 
ATOM   4291 C  C     . ARG C 1 142 ? 94.446  93.938  110.669 1.00 103.54 ? 142 ARG B C     1 
ATOM   4292 O  O     . ARG C 1 142 ? 93.934  94.050  111.788 1.00 102.19 ? 142 ARG B O     1 
ATOM   4293 C  CB    . ARG C 1 142 ? 92.451  93.173  109.384 1.00 116.77 ? 142 ARG B CB    1 
ATOM   4294 C  CG    . ARG C 1 142 ? 91.083  93.762  109.677 1.00 119.27 ? 142 ARG B CG    1 
ATOM   4295 C  CD    . ARG C 1 142 ? 89.984  92.994  108.960 1.00 121.08 ? 142 ARG B CD    1 
ATOM   4296 N  NE    . ARG C 1 142 ? 90.041  93.181  107.515 1.00 129.51 ? 142 ARG B NE    1 
ATOM   4297 C  CZ    . ARG C 1 142 ? 90.594  92.325  106.666 1.00 130.44 ? 142 ARG B CZ    1 
ATOM   4298 N  NH1   . ARG C 1 142 ? 91.143  91.195  107.083 1.00 130.84 ? 142 ARG B NH1   1 
ATOM   4299 N  NH2   . ARG C 1 142 ? 90.597  92.609  105.367 1.00 125.58 ? 142 ARG B NH2   1 
ATOM   4300 N  N     . ARG C 1 143 ? 95.721  93.601  110.498 1.00 105.91 ? 143 ARG B N     1 
ATOM   4301 C  CA    . ARG C 1 143 ? 96.630  93.360  111.608 1.00 105.41 ? 143 ARG B CA    1 
ATOM   4302 C  C     . ARG C 1 143 ? 97.470  94.583  111.951 1.00 100.49 ? 143 ARG B C     1 
ATOM   4303 O  O     . ARG C 1 143 ? 98.369  94.489  112.791 1.00 96.20  ? 143 ARG B O     1 
ATOM   4304 C  CB    . ARG C 1 143 ? 97.542  92.174  111.293 1.00 106.13 ? 143 ARG B CB    1 
ATOM   4305 C  CG    . ARG C 1 143 ? 96.846  90.828  111.311 1.00 104.28 ? 143 ARG B CG    1 
ATOM   4306 C  CD    . ARG C 1 143 ? 97.848  89.691  111.230 1.00 106.76 ? 143 ARG B CD    1 
ATOM   4307 N  NE    . ARG C 1 143 ? 97.287  88.435  111.713 1.00 113.96 ? 143 ARG B NE    1 
ATOM   4308 C  CZ    . ARG C 1 143 ? 97.408  87.272  111.089 1.00 115.71 ? 143 ARG B CZ    1 
ATOM   4309 N  NH1   . ARG C 1 143 ? 98.067  87.165  109.946 1.00 116.35 ? 143 ARG B NH1   1 
ATOM   4310 N  NH2   . ARG C 1 143 ? 96.856  86.187  111.625 1.00 120.79 ? 143 ARG B NH2   1 
ATOM   4311 N  N     . GLN C 1 144 ? 97.201  95.721  111.317 1.00 95.78  ? 144 GLN B N     1 
ATOM   4312 C  CA    . GLN C 1 144 ? 97.995  96.916  111.543 1.00 90.29  ? 144 GLN B CA    1 
ATOM   4313 C  C     . GLN C 1 144 ? 97.801  97.430  112.966 1.00 89.34  ? 144 GLN B C     1 
ATOM   4314 O  O     . GLN C 1 144 ? 96.812  97.129  113.638 1.00 90.96  ? 144 GLN B O     1 
ATOM   4315 C  CB    . GLN C 1 144 ? 97.625  98.000  110.533 1.00 90.95  ? 144 GLN B CB    1 
ATOM   4316 C  CG    . GLN C 1 144 ? 97.832  97.577  109.095 1.00 92.07  ? 144 GLN B CG    1 
ATOM   4317 C  CD    . GLN C 1 144 ? 97.283  98.583  108.111 1.00 98.54  ? 144 GLN B CD    1 
ATOM   4318 O  OE1   . GLN C 1 144 ? 96.888  98.227  107.003 1.00 103.51 ? 144 GLN B OE1   1 
ATOM   4319 N  NE2   . GLN C 1 144 ? 97.262  99.848  108.507 1.00 98.89  ? 144 GLN B NE2   1 
ATOM   4320 N  N     . VAL C 1 145 ? 98.771  98.222  113.422 1.00 86.85  ? 145 VAL B N     1 
ATOM   4321 C  CA    . VAL C 1 145 ? 98.829  98.671  114.804 1.00 83.42  ? 145 VAL B CA    1 
ATOM   4322 C  C     . VAL C 1 145 ? 98.981  100.186 114.830 1.00 81.33  ? 145 VAL B C     1 
ATOM   4323 O  O     . VAL C 1 145 ? 99.447  100.806 113.871 1.00 90.08  ? 145 VAL B O     1 
ATOM   4324 C  CB    . VAL C 1 145 ? 99.981  97.988  115.573 1.00 82.47  ? 145 VAL B CB    1 
ATOM   4325 C  CG1   . VAL C 1 145 ? 101.284 98.739  115.380 1.00 79.69  ? 145 VAL B CG1   1 
ATOM   4326 C  CG2   . VAL C 1 145 ? 99.644  97.857  117.036 1.00 83.88  ? 145 VAL B CG2   1 
ATOM   4327 N  N     . ALA C 1 146 ? 98.558  100.784 115.943 1.00 77.04  ? 146 ALA B N     1 
ATOM   4328 C  CA    . ALA C 1 146 ? 98.620  102.225 116.144 1.00 77.52  ? 146 ALA B CA    1 
ATOM   4329 C  C     . ALA C 1 146 ? 99.179  102.516 117.527 1.00 80.14  ? 146 ALA B C     1 
ATOM   4330 O  O     . ALA C 1 146 ? 98.711  101.951 118.523 1.00 81.06  ? 146 ALA B O     1 
ATOM   4331 C  CB    . ALA C 1 146 ? 97.241  102.869 115.989 1.00 75.99  ? 146 ALA B CB    1 
ATOM   4332 N  N     . VAL C 1 147 ? 100.167 103.402 117.588 1.00 78.22  ? 147 VAL B N     1 
ATOM   4333 C  CA    . VAL C 1 147 ? 100.827 103.780 118.831 1.00 69.10  ? 147 VAL B CA    1 
ATOM   4334 C  C     . VAL C 1 147 ? 100.364 105.182 119.199 1.00 72.74  ? 147 VAL B C     1 
ATOM   4335 O  O     . VAL C 1 147 ? 100.583 106.134 118.440 1.00 75.60  ? 147 VAL B O     1 
ATOM   4336 C  CB    . VAL C 1 147 ? 102.355 103.723 118.698 1.00 62.42  ? 147 VAL B CB    1 
ATOM   4337 C  CG1   . VAL C 1 147 ? 103.017 104.478 119.835 1.00 60.28  ? 147 VAL B CG1   1 
ATOM   4338 C  CG2   . VAL C 1 147 ? 102.828 102.282 118.662 1.00 64.03  ? 147 VAL B CG2   1 
ATOM   4339 N  N     . LEU C 1 148 ? 99.729  105.313 120.360 1.00 71.75  ? 148 LEU B N     1 
ATOM   4340 C  CA    . LEU C 1 148 ? 99.206  106.583 120.837 1.00 64.43  ? 148 LEU B CA    1 
ATOM   4341 C  C     . LEU C 1 148 ? 99.994  107.035 122.057 1.00 64.47  ? 148 LEU B C     1 
ATOM   4342 O  O     . LEU C 1 148 ? 100.143 106.277 123.023 1.00 69.71  ? 148 LEU B O     1 
ATOM   4343 C  CB    . LEU C 1 148 ? 97.723  106.466 121.186 1.00 56.13  ? 148 LEU B CB    1 
ATOM   4344 C  CG    . LEU C 1 148 ? 96.857  105.739 120.162 1.00 65.88  ? 148 LEU B CG    1 
ATOM   4345 C  CD1   . LEU C 1 148 ? 95.517  105.375 120.770 1.00 74.84  ? 148 LEU B CD1   1 
ATOM   4346 C  CD2   . LEU C 1 148 ? 96.673  106.597 118.924 1.00 73.68  ? 148 LEU B CD2   1 
ATOM   4347 N  N     . ASN C 1 149 ? 100.494 108.265 122.005 1.00 55.62  ? 149 ASN B N     1 
ATOM   4348 C  CA    . ASN C 1 149 ? 101.155 108.898 123.142 1.00 56.57  ? 149 ASN B CA    1 
ATOM   4349 C  C     . ASN C 1 149 ? 100.092 109.691 123.890 1.00 63.75  ? 149 ASN B C     1 
ATOM   4350 O  O     . ASN C 1 149 ? 99.756  110.815 123.510 1.00 72.33  ? 149 ASN B O     1 
ATOM   4351 C  CB    . ASN C 1 149 ? 102.303 109.784 122.670 1.00 57.08  ? 149 ASN B CB    1 
ATOM   4352 C  CG    . ASN C 1 149 ? 103.080 110.401 123.815 1.00 60.46  ? 149 ASN B CG    1 
ATOM   4353 O  OD1   . ASN C 1 149 ? 102.868 110.064 124.978 1.00 69.90  ? 149 ASN B OD1   1 
ATOM   4354 N  ND2   . ASN C 1 149 ? 103.985 111.313 123.489 1.00 52.95  ? 149 ASN B ND2   1 
ATOM   4355 N  N     . LEU C 1 150 ? 99.553  109.100 124.952 1.00 59.06  ? 150 LEU B N     1 
ATOM   4356 C  CA    . LEU C 1 150 ? 98.436  109.710 125.657 1.00 60.61  ? 150 LEU B CA    1 
ATOM   4357 C  C     . LEU C 1 150 ? 98.872  111.010 126.329 1.00 61.31  ? 150 LEU B C     1 
ATOM   4358 O  O     . LEU C 1 150 ? 100.006 111.116 126.803 1.00 59.26  ? 150 LEU B O     1 
ATOM   4359 C  CB    . LEU C 1 150 ? 97.871  108.742 126.695 1.00 63.12  ? 150 LEU B CB    1 
ATOM   4360 C  CG    . LEU C 1 150 ? 97.161  107.511 126.128 1.00 60.39  ? 150 LEU B CG    1 
ATOM   4361 C  CD1   . LEU C 1 150 ? 96.363  106.803 127.205 1.00 67.61  ? 150 LEU B CD1   1 
ATOM   4362 C  CD2   . LEU C 1 150 ? 96.263  107.896 124.966 1.00 61.18  ? 150 LEU B CD2   1 
ATOM   4363 N  N     . PRO C 1 151 ? 97.990  112.016 126.393 1.00 67.40  ? 151 PRO B N     1 
ATOM   4364 C  CA    . PRO C 1 151 ? 98.386  113.314 126.957 1.00 69.60  ? 151 PRO B CA    1 
ATOM   4365 C  C     . PRO C 1 151 ? 98.526  113.286 128.469 1.00 77.15  ? 151 PRO B C     1 
ATOM   4366 O  O     . PRO C 1 151 ? 98.427  112.228 129.097 1.00 81.42  ? 151 PRO B O     1 
ATOM   4367 C  CB    . PRO C 1 151 ? 97.257  114.255 126.519 1.00 65.62  ? 151 PRO B CB    1 
ATOM   4368 C  CG    . PRO C 1 151 ? 96.105  113.386 126.217 1.00 69.83  ? 151 PRO B CG    1 
ATOM   4369 C  CD    . PRO C 1 151 ? 96.596  112.003 125.924 1.00 73.33  ? 151 PRO B CD    1 
ATOM   4370 N  N     . ARG C 1 152 ? 98.769  114.459 129.058 1.00 78.23  ? 152 ARG B N     1 
ATOM   4371 C  CA    . ARG C 1 152 ? 99.099  114.531 130.477 1.00 79.34  ? 152 ARG B CA    1 
ATOM   4372 C  C     . ARG C 1 152 ? 97.916  114.126 131.351 1.00 83.89  ? 152 ARG B C     1 
ATOM   4373 O  O     . ARG C 1 152 ? 98.076  113.363 132.309 1.00 83.19  ? 152 ARG B O     1 
ATOM   4374 C  CB    . ARG C 1 152 ? 99.570  115.943 130.826 1.00 76.42  ? 152 ARG B CB    1 
ATOM   4375 C  CG    . ARG C 1 152 ? 100.060 116.103 132.252 1.00 72.22  ? 152 ARG B CG    1 
ATOM   4376 C  CD    . ARG C 1 152 ? 101.366 115.359 132.468 1.00 67.19  ? 152 ARG B CD    1 
ATOM   4377 N  NE    . ARG C 1 152 ? 102.518 116.251 132.446 1.00 60.89  ? 152 ARG B NE    1 
ATOM   4378 C  CZ    . ARG C 1 152 ? 103.749 115.891 132.777 1.00 56.81  ? 152 ARG B CZ    1 
ATOM   4379 N  NH1   . ARG C 1 152 ? 104.029 114.654 133.152 1.00 57.73  ? 152 ARG B NH1   1 
ATOM   4380 N  NH2   . ARG C 1 152 ? 104.725 116.793 132.727 1.00 53.96  ? 152 ARG B NH2   1 
ATOM   4381 N  N     . SER C 1 153 ? 96.721  114.620 131.038 1.00 82.11  ? 153 SER B N     1 
ATOM   4382 C  CA    . SER C 1 153 ? 95.545  114.418 131.883 1.00 83.43  ? 153 SER B CA    1 
ATOM   4383 C  C     . SER C 1 153 ? 94.386  113.854 131.073 1.00 86.98  ? 153 SER B C     1 
ATOM   4384 O  O     . SER C 1 153 ? 93.253  114.334 131.143 1.00 97.33  ? 153 SER B O     1 
ATOM   4385 C  CB    . SER C 1 153 ? 95.138  115.718 132.566 1.00 84.38  ? 153 SER B CB    1 
ATOM   4386 O  OG    . SER C 1 153 ? 93.916  115.561 133.267 1.00 86.20  ? 153 SER B OG    1 
ATOM   4387 N  N     . PHE C 1 154 ? 94.658  112.815 130.289 1.00 80.60  ? 154 PHE B N     1 
ATOM   4388 C  CA    . PHE C 1 154 ? 93.623  112.189 129.483 1.00 83.52  ? 154 PHE B CA    1 
ATOM   4389 C  C     . PHE C 1 154 ? 92.637  111.427 130.368 1.00 91.40  ? 154 PHE B C     1 
ATOM   4390 O  O     . PHE C 1 154 ? 92.795  111.324 131.587 1.00 92.60  ? 154 PHE B O     1 
ATOM   4391 C  CB    . PHE C 1 154 ? 94.245  111.245 128.456 1.00 79.88  ? 154 PHE B CB    1 
ATOM   4392 C  CG    . PHE C 1 154 ? 93.359  110.956 127.279 1.00 85.24  ? 154 PHE B CG    1 
ATOM   4393 C  CD1   . PHE C 1 154 ? 92.486  111.916 126.800 1.00 88.70  ? 154 PHE B CD1   1 
ATOM   4394 C  CD2   . PHE C 1 154 ? 93.397  109.722 126.654 1.00 82.02  ? 154 PHE B CD2   1 
ATOM   4395 C  CE1   . PHE C 1 154 ? 91.669  111.652 125.719 1.00 87.19  ? 154 PHE B CE1   1 
ATOM   4396 C  CE2   . PHE C 1 154 ? 92.582  109.453 125.573 1.00 86.42  ? 154 PHE B CE2   1 
ATOM   4397 C  CZ    . PHE C 1 154 ? 91.717  110.419 125.106 1.00 89.46  ? 154 PHE B CZ    1 
ATOM   4398 N  N     . ASP C 1 155 ? 91.593  110.899 129.732 1.00 94.87  ? 155 ASP B N     1 
ATOM   4399 C  CA    . ASP C 1 155 ? 90.644  110.012 130.392 1.00 93.98  ? 155 ASP B CA    1 
ATOM   4400 C  C     . ASP C 1 155 ? 90.873  108.550 130.045 1.00 91.21  ? 155 ASP B C     1 
ATOM   4401 O  O     . ASP C 1 155 ? 90.522  107.674 130.843 1.00 92.02  ? 155 ASP B O     1 
ATOM   4402 C  CB    . ASP C 1 155 ? 89.210  110.403 130.019 1.00 96.15  ? 155 ASP B CB    1 
ATOM   4403 C  CG    . ASP C 1 155 ? 88.207  110.060 131.104 1.00 105.11 ? 155 ASP B CG    1 
ATOM   4404 O  OD1   . ASP C 1 155 ? 88.503  109.184 131.942 1.00 105.15 ? 155 ASP B OD1   1 
ATOM   4405 O  OD2   . ASP C 1 155 ? 87.118  110.672 131.117 1.00 107.99 ? 155 ASP B OD2   1 
ATOM   4406 N  N     . TRP C 1 156 ? 91.416  108.277 128.856 1.00 90.41  ? 156 TRP B N     1 
ATOM   4407 C  CA    . TRP C 1 156 ? 91.853  106.954 128.416 1.00 94.13  ? 156 TRP B CA    1 
ATOM   4408 C  C     . TRP C 1 156 ? 90.664  106.042 128.124 1.00 97.90  ? 156 TRP B C     1 
ATOM   4409 O  O     . TRP C 1 156 ? 90.821  104.968 127.534 1.00 101.09 ? 156 TRP B O     1 
ATOM   4410 C  CB    . TRP C 1 156 ? 92.794  106.333 129.460 1.00 93.31  ? 156 TRP B CB    1 
ATOM   4411 C  CG    . TRP C 1 156 ? 92.830  104.847 129.432 1.00 92.29  ? 156 TRP B CG    1 
ATOM   4412 C  CD1   . TRP C 1 156 ? 93.469  104.060 128.522 1.00 91.48  ? 156 TRP B CD1   1 
ATOM   4413 C  CD2   . TRP C 1 156 ? 92.168  103.959 130.337 1.00 95.45  ? 156 TRP B CD2   1 
ATOM   4414 N  NE1   . TRP C 1 156 ? 93.256  102.736 128.810 1.00 95.31  ? 156 TRP B NE1   1 
ATOM   4415 C  CE2   . TRP C 1 156 ? 92.461  102.647 129.922 1.00 100.20 ? 156 TRP B CE2   1 
ATOM   4416 C  CE3   . TRP C 1 156 ? 91.363  104.146 131.463 1.00 97.34  ? 156 TRP B CE3   1 
ATOM   4417 C  CZ2   . TRP C 1 156 ? 91.976  101.529 130.592 1.00 100.45 ? 156 TRP B CZ2   1 
ATOM   4418 C  CZ3   . TRP C 1 156 ? 90.884  103.036 132.126 1.00 95.55  ? 156 TRP B CZ3   1 
ATOM   4419 C  CH2   . TRP C 1 156 ? 91.191  101.744 131.690 1.00 94.85  ? 156 TRP B CH2   1 
ATOM   4420 N  N     . VAL C 1 157 ? 89.459  106.489 128.466 1.00 95.91  ? 157 VAL B N     1 
ATOM   4421 C  CA    . VAL C 1 157 ? 88.256  105.707 128.213 1.00 97.48  ? 157 VAL B CA    1 
ATOM   4422 C  C     . VAL C 1 157 ? 87.544  106.306 127.007 1.00 102.94 ? 157 VAL B C     1 
ATOM   4423 O  O     . VAL C 1 157 ? 86.792  105.619 126.305 1.00 110.18 ? 157 VAL B O     1 
ATOM   4424 C  CB    . VAL C 1 157 ? 87.366  105.651 129.470 1.00 96.86  ? 157 VAL B CB    1 
ATOM   4425 C  CG1   . VAL C 1 157 ? 85.913  105.395 129.123 1.00 103.26 ? 157 VAL B CG1   1 
ATOM   4426 C  CG2   . VAL C 1 157 ? 87.870  104.557 130.392 1.00 95.16  ? 157 VAL B CG2   1 
ATOM   4427 N  N     . SER C 1 158 ? 87.826  107.579 126.721 1.00 96.71  ? 158 SER B N     1 
ATOM   4428 C  CA    . SER C 1 158 ? 87.301  108.197 125.511 1.00 97.69  ? 158 SER B CA    1 
ATOM   4429 C  C     . SER C 1 158 ? 87.767  107.476 124.253 1.00 101.84 ? 158 SER B C     1 
ATOM   4430 O  O     . SER C 1 158 ? 87.129  107.608 123.204 1.00 104.34 ? 158 SER B O     1 
ATOM   4431 C  CB    . SER C 1 158 ? 87.707  109.669 125.454 1.00 95.61  ? 158 SER B CB    1 
ATOM   4432 O  OG    . SER C 1 158 ? 87.301  110.353 126.626 1.00 103.20 ? 158 SER B OG    1 
ATOM   4433 N  N     . LEU C 1 159 ? 88.866  106.721 124.335 1.00 95.20  ? 159 LEU B N     1 
ATOM   4434 C  CA    . LEU C 1 159 ? 89.294  105.909 123.202 1.00 91.29  ? 159 LEU B CA    1 
ATOM   4435 C  C     . LEU C 1 159 ? 88.293  104.804 122.895 1.00 94.69  ? 159 LEU B C     1 
ATOM   4436 O  O     . LEU C 1 159 ? 88.163  104.390 121.738 1.00 99.13  ? 159 LEU B O     1 
ATOM   4437 C  CB    . LEU C 1 159 ? 90.670  105.305 123.478 1.00 86.85  ? 159 LEU B CB    1 
ATOM   4438 C  CG    . LEU C 1 159 ? 91.839  106.266 123.689 1.00 81.96  ? 159 LEU B CG    1 
ATOM   4439 C  CD1   . LEU C 1 159 ? 93.155  105.514 123.622 1.00 78.71  ? 159 LEU B CD1   1 
ATOM   4440 C  CD2   . LEU C 1 159 ? 91.808  107.381 122.663 1.00 81.96  ? 159 LEU B CD2   1 
ATOM   4441 N  N     . LEU C 1 160 ? 87.586  104.314 123.910 1.00 94.12  ? 160 LEU B N     1 
ATOM   4442 C  CA    . LEU C 1 160 ? 86.704  103.169 123.739 1.00 99.29  ? 160 LEU B CA    1 
ATOM   4443 C  C     . LEU C 1 160 ? 85.522  103.505 122.837 1.00 104.54 ? 160 LEU B C     1 
ATOM   4444 O  O     . LEU C 1 160 ? 85.053  104.645 122.781 1.00 102.54 ? 160 LEU B O     1 
ATOM   4445 C  CB    . LEU C 1 160 ? 86.195  102.682 125.094 1.00 100.71 ? 160 LEU B CB    1 
ATOM   4446 C  CG    . LEU C 1 160 ? 87.210  101.954 125.975 1.00 103.61 ? 160 LEU B CG    1 
ATOM   4447 C  CD1   . LEU C 1 160 ? 86.549  101.451 127.244 1.00 107.91 ? 160 LEU B CD1   1 
ATOM   4448 C  CD2   . LEU C 1 160 ? 87.849  100.807 125.215 1.00 99.45  ? 160 LEU B CD2   1 
ATOM   4449 N  N     . VAL C 1 161 ? 85.048  102.488 122.124 1.00 108.22 ? 161 VAL B N     1 
ATOM   4450 C  CA    . VAL C 1 161 ? 83.865  102.630 121.269 1.00 108.75 ? 161 VAL B CA    1 
ATOM   4451 C  C     . VAL C 1 161 ? 82.660  102.967 122.142 1.00 110.85 ? 161 VAL B C     1 
ATOM   4452 O  O     . VAL C 1 161 ? 82.461  102.326 123.193 1.00 113.10 ? 161 VAL B O     1 
ATOM   4453 C  CB    . VAL C 1 161 ? 83.635  101.334 120.464 1.00 107.70 ? 161 VAL B CB    1 
ATOM   4454 C  CG1   . VAL C 1 161 ? 83.783  100.113 121.361 1.00 105.18 ? 161 VAL B CG1   1 
ATOM   4455 C  CG2   . VAL C 1 161 ? 82.284  101.335 119.774 1.00 109.34 ? 161 VAL B CG2   1 
ATOM   4456 N  N     . PRO C 1 162 ? 81.840  103.960 121.781 1.00 109.49 ? 162 PRO B N     1 
ATOM   4457 C  CA    . PRO C 1 162 ? 80.781  104.405 122.704 1.00 109.80 ? 162 PRO B CA    1 
ATOM   4458 C  C     . PRO C 1 162 ? 79.748  103.344 123.037 1.00 110.67 ? 162 PRO B C     1 
ATOM   4459 O  O     . PRO C 1 162 ? 79.068  103.474 124.062 1.00 109.65 ? 162 PRO B O     1 
ATOM   4460 C  CB    . PRO C 1 162 ? 80.155  105.595 121.967 1.00 108.95 ? 162 PRO B CB    1 
ATOM   4461 C  CG    . PRO C 1 162 ? 80.410  105.324 120.532 1.00 110.64 ? 162 PRO B CG    1 
ATOM   4462 C  CD    . PRO C 1 162 ? 81.750  104.638 120.476 1.00 107.41 ? 162 PRO B CD    1 
ATOM   4463 N  N     . GLU C 1 163 ? 79.596  102.303 122.216 1.00 114.37 ? 163 GLU B N     1 
ATOM   4464 C  CA    . GLU C 1 163 ? 78.713  101.207 122.597 1.00 115.99 ? 163 GLU B CA    1 
ATOM   4465 C  C     . GLU C 1 163 ? 79.261  100.423 123.783 1.00 116.16 ? 163 GLU B C     1 
ATOM   4466 O  O     . GLU C 1 163 ? 78.486  99.775  124.493 1.00 114.13 ? 163 GLU B O     1 
ATOM   4467 C  CB    . GLU C 1 163 ? 78.474  100.271 121.410 1.00 117.59 ? 163 GLU B CB    1 
ATOM   4468 C  CG    . GLU C 1 163 ? 79.637  99.349  121.083 1.00 118.66 ? 163 GLU B CG    1 
ATOM   4469 C  CD    . GLU C 1 163 ? 79.403  97.926  121.550 1.00 122.58 ? 163 GLU B CD    1 
ATOM   4470 O  OE1   . GLU C 1 163 ? 78.238  97.575  121.831 1.00 127.62 ? 163 GLU B OE1   1 
ATOM   4471 O  OE2   . GLU C 1 163 ? 80.384  97.158  121.637 1.00 120.44 ? 163 GLU B OE2   1 
ATOM   4472 N  N     . SER C 1 164 ? 80.574  100.471 124.011 1.00 116.24 ? 164 SER B N     1 
ATOM   4473 C  CA    . SER C 1 164 ? 81.200  99.843  125.165 1.00 111.87 ? 164 SER B CA    1 
ATOM   4474 C  C     . SER C 1 164 ? 81.721  100.856 126.172 1.00 110.72 ? 164 SER B C     1 
ATOM   4475 O  O     . SER C 1 164 ? 82.276  100.459 127.201 1.00 109.18 ? 164 SER B O     1 
ATOM   4476 C  CB    . SER C 1 164 ? 82.343  98.926  124.716 1.00 108.53 ? 164 SER B CB    1 
ATOM   4477 O  OG    . SER C 1 164 ? 83.275  98.728  125.764 1.00 107.38 ? 164 SER B OG    1 
ATOM   4478 N  N     . GLN C 1 165 ? 81.576  102.150 125.895 1.00 114.39 ? 165 GLN B N     1 
ATOM   4479 C  CA    . GLN C 1 165 ? 81.923  103.193 126.849 1.00 113.60 ? 165 GLN B CA    1 
ATOM   4480 C  C     . GLN C 1 165 ? 80.765  103.557 127.765 1.00 113.16 ? 165 GLN B C     1 
ATOM   4481 O  O     . GLN C 1 165 ? 80.996  104.090 128.857 1.00 114.07 ? 165 GLN B O     1 
ATOM   4482 C  CB    . GLN C 1 165 ? 82.396  104.446 126.103 1.00 114.57 ? 165 GLN B CB    1 
ATOM   4483 C  CG    . GLN C 1 165 ? 83.014  105.514 126.983 1.00 109.79 ? 165 GLN B CG    1 
ATOM   4484 C  CD    . GLN C 1 165 ? 83.545  106.686 126.187 1.00 112.85 ? 165 GLN B CD    1 
ATOM   4485 O  OE1   . GLN C 1 165 ? 84.401  107.433 126.659 1.00 114.66 ? 165 GLN B OE1   1 
ATOM   4486 N  NE2   . GLN C 1 165 ? 83.042  106.852 124.970 1.00 108.88 ? 165 GLN B NE2   1 
ATOM   4487 N  N     . GLU C 1 166 ? 79.530  103.273 127.346 1.00 113.06 ? 166 GLU B N     1 
ATOM   4488 C  CA    . GLU C 1 166 ? 78.369  103.618 128.158 1.00 114.65 ? 166 GLU B CA    1 
ATOM   4489 C  C     . GLU C 1 166 ? 78.359  102.842 129.468 1.00 114.86 ? 166 GLU B C     1 
ATOM   4490 O  O     . GLU C 1 166 ? 77.983  103.385 130.512 1.00 114.81 ? 166 GLU B O     1 
ATOM   4491 C  CB    . GLU C 1 166 ? 77.085  103.362 127.370 1.00 117.11 ? 166 GLU B CB    1 
ATOM   4492 C  CG    . GLU C 1 166 ? 76.047  104.462 127.509 1.00 120.91 ? 166 GLU B CG    1 
ATOM   4493 C  CD    . GLU C 1 166 ? 76.508  105.774 126.904 1.00 129.05 ? 166 GLU B CD    1 
ATOM   4494 O  OE1   . GLU C 1 166 ? 77.163  105.743 125.842 1.00 130.77 ? 166 GLU B OE1   1 
ATOM   4495 O  OE2   . GLU C 1 166 ? 76.216  106.837 127.493 1.00 133.11 ? 166 GLU B OE2   1 
ATOM   4496 N  N     . VAL C 1 167 ? 78.763  101.569 129.434 1.00 114.12 ? 167 VAL B N     1 
ATOM   4497 C  CA    . VAL C 1 167 ? 78.808  100.769 130.655 1.00 114.28 ? 167 VAL B CA    1 
ATOM   4498 C  C     . VAL C 1 167 ? 79.814  101.351 131.643 1.00 115.01 ? 167 VAL B C     1 
ATOM   4499 O  O     . VAL C 1 167 ? 79.532  101.471 132.841 1.00 114.10 ? 167 VAL B O     1 
ATOM   4500 C  CB    . VAL C 1 167 ? 79.118  99.298  130.319 1.00 110.87 ? 167 VAL B CB    1 
ATOM   4501 C  CG1   . VAL C 1 167 ? 80.158  99.210  129.221 1.00 111.07 ? 167 VAL B CG1   1 
ATOM   4502 C  CG2   . VAL C 1 167 ? 79.589  98.554  131.558 1.00 107.78 ? 167 VAL B CG2   1 
ATOM   4503 N  N     . ILE C 1 168 ? 80.998  101.730 131.158 1.00 113.70 ? 168 ILE B N     1 
ATOM   4504 C  CA    . ILE C 1 168 ? 82.010  102.310 132.038 1.00 106.09 ? 168 ILE B CA    1 
ATOM   4505 C  C     . ILE C 1 168 ? 81.528  103.645 132.595 1.00 110.64 ? 168 ILE B C     1 
ATOM   4506 O  O     . ILE C 1 168 ? 81.702  103.944 133.785 1.00 111.30 ? 168 ILE B O     1 
ATOM   4507 C  CB    . ILE C 1 168 ? 83.345  102.453 131.286 1.00 102.70 ? 168 ILE B CB    1 
ATOM   4508 C  CG1   . ILE C 1 168 ? 84.161  101.168 131.413 1.00 98.60  ? 168 ILE B CG1   1 
ATOM   4509 C  CG2   . ILE C 1 168 ? 84.147  103.628 131.820 1.00 102.14 ? 168 ILE B CG2   1 
ATOM   4510 C  CD1   . ILE C 1 168 ? 84.566  100.852 132.823 1.00 98.27  ? 168 ILE B CD1   1 
ATOM   4511 N  N     . GLU C 1 169 ? 80.912  104.469 131.741 1.00 115.42 ? 169 GLU B N     1 
ATOM   4512 C  CA    . GLU C 1 169 ? 80.420  105.767 132.189 1.00 113.51 ? 169 GLU B CA    1 
ATOM   4513 C  C     . GLU C 1 169 ? 79.329  105.614 133.241 1.00 110.12 ? 169 GLU B C     1 
ATOM   4514 O  O     . GLU C 1 169 ? 79.302  106.357 134.227 1.00 110.76 ? 169 GLU B O     1 
ATOM   4515 C  CB    . GLU C 1 169 ? 79.910  106.577 130.998 1.00 120.60 ? 169 GLU B CB    1 
ATOM   4516 C  CG    . GLU C 1 169 ? 81.005  107.278 130.209 1.00 128.65 ? 169 GLU B CG    1 
ATOM   4517 C  CD    . GLU C 1 169 ? 81.841  108.212 131.064 1.00 133.04 ? 169 GLU B CD    1 
ATOM   4518 O  OE1   . GLU C 1 169 ? 81.276  108.859 131.972 1.00 135.46 ? 169 GLU B OE1   1 
ATOM   4519 O  OE2   . GLU C 1 169 ? 83.063  108.302 130.827 1.00 125.84 ? 169 GLU B OE2   1 
ATOM   4520 N  N     . GLU C 1 170 ? 78.422  104.651 133.057 1.00 110.16 ? 170 GLU B N     1 
ATOM   4521 C  CA    . GLU C 1 170 ? 77.367  104.449 134.044 1.00 112.06 ? 170 GLU B CA    1 
ATOM   4522 C  C     . GLU C 1 170 ? 77.912  103.829 135.324 1.00 110.11 ? 170 GLU B C     1 
ATOM   4523 O  O     . GLU C 1 170 ? 77.383  104.095 136.407 1.00 109.74 ? 170 GLU B O     1 
ATOM   4524 C  CB    . GLU C 1 170 ? 76.230  103.612 133.441 1.00 114.48 ? 170 GLU B CB    1 
ATOM   4525 C  CG    . GLU C 1 170 ? 76.513  102.131 133.186 1.00 117.20 ? 170 GLU B CG    1 
ATOM   4526 C  CD    . GLU C 1 170 ? 76.468  101.275 134.439 1.00 118.80 ? 170 GLU B CD    1 
ATOM   4527 O  OE1   . GLU C 1 170 ? 77.036  100.163 134.420 1.00 117.03 ? 170 GLU B OE1   1 
ATOM   4528 O  OE2   . GLU C 1 170 ? 75.856  101.709 135.437 1.00 119.96 ? 170 GLU B OE2   1 
ATOM   4529 N  N     . PHE C 1 171 ? 78.966  103.015 135.229 1.00 111.06 ? 171 PHE B N     1 
ATOM   4530 C  CA    . PHE C 1 171 ? 79.635  102.525 136.431 1.00 108.95 ? 171 PHE B CA    1 
ATOM   4531 C  C     . PHE C 1 171 ? 80.208  103.691 137.231 1.00 104.05 ? 171 PHE B C     1 
ATOM   4532 O  O     . PHE C 1 171 ? 80.003  103.790 138.450 1.00 98.44  ? 171 PHE B O     1 
ATOM   4533 C  CB    . PHE C 1 171 ? 80.738  101.536 136.034 1.00 107.13 ? 171 PHE B CB    1 
ATOM   4534 C  CG    . PHE C 1 171 ? 81.588  101.047 137.181 1.00 102.55 ? 171 PHE B CG    1 
ATOM   4535 C  CD1   . PHE C 1 171 ? 82.861  100.559 136.942 1.00 101.53 ? 171 PHE B CD1   1 
ATOM   4536 C  CD2   . PHE C 1 171 ? 81.096  100.998 138.476 1.00 100.86 ? 171 PHE B CD2   1 
ATOM   4537 C  CE1   . PHE C 1 171 ? 83.648  100.093 137.976 1.00 96.75  ? 171 PHE B CE1   1 
ATOM   4538 C  CE2   . PHE C 1 171 ? 81.879  100.532 139.513 1.00 101.35 ? 171 PHE B CE2   1 
ATOM   4539 C  CZ    . PHE C 1 171 ? 83.155  100.075 139.261 1.00 97.97  ? 171 PHE B CZ    1 
ATOM   4540 N  N     . ARG C 1 172 ? 80.916  104.597 136.552 1.00 106.97 ? 172 ARG B N     1 
ATOM   4541 C  CA    . ARG C 1 172 ? 81.449  105.770 137.240 1.00 105.41 ? 172 ARG B CA    1 
ATOM   4542 C  C     . ARG C 1 172 ? 80.333  106.640 137.802 1.00 107.84 ? 172 ARG B C     1 
ATOM   4543 O  O     . ARG C 1 172 ? 80.472  107.209 138.888 1.00 108.30 ? 172 ARG B O     1 
ATOM   4544 C  CB    . ARG C 1 172 ? 82.339  106.592 136.310 1.00 107.36 ? 172 ARG B CB    1 
ATOM   4545 C  CG    . ARG C 1 172 ? 83.761  106.085 136.186 1.00 101.75 ? 172 ARG B CG    1 
ATOM   4546 C  CD    . ARG C 1 172 ? 84.589  107.057 135.368 1.00 105.23 ? 172 ARG B CD    1 
ATOM   4547 N  NE    . ARG C 1 172 ? 85.535  106.395 134.480 1.00 113.61 ? 172 ARG B NE    1 
ATOM   4548 C  CZ    . ARG C 1 172 ? 86.373  107.036 133.679 1.00 113.68 ? 172 ARG B CZ    1 
ATOM   4549 N  NH1   . ARG C 1 172 ? 86.395  108.357 133.615 1.00 116.86 ? 172 ARG B NH1   1 
ATOM   4550 N  NH2   . ARG C 1 172 ? 87.214  106.335 132.926 1.00 106.02 ? 172 ARG B NH2   1 
ATOM   4551 N  N     . ALA C 1 173 ? 79.226  106.773 137.069 1.00 109.68 ? 173 ALA B N     1 
ATOM   4552 C  CA    . ALA C 1 173 ? 78.108  107.576 137.555 1.00 108.83 ? 173 ALA B CA    1 
ATOM   4553 C  C     . ALA C 1 173 ? 77.483  106.960 138.800 1.00 109.29 ? 173 ALA B C     1 
ATOM   4554 O  O     . ALA C 1 173 ? 77.120  107.678 139.739 1.00 109.58 ? 173 ALA B O     1 
ATOM   4555 C  CB    . ALA C 1 173 ? 77.062  107.742 136.454 1.00 106.49 ? 173 ALA B CB    1 
ATOM   4556 N  N     . GLY C 1 174 ? 77.340  105.634 138.824 1.00 108.42 ? 174 GLY B N     1 
ATOM   4557 C  CA    . GLY C 1 174 ? 76.827  104.976 140.013 1.00 106.24 ? 174 GLY B CA    1 
ATOM   4558 C  C     . GLY C 1 174 ? 77.765  105.114 141.195 1.00 106.50 ? 174 GLY B C     1 
ATOM   4559 O  O     . GLY C 1 174 ? 77.323  105.236 142.340 1.00 108.62 ? 174 GLY B O     1 
ATOM   4560 N  N     . LEU C 1 175 ? 79.074  105.087 140.935 1.00 105.99 ? 175 LEU B N     1 
ATOM   4561 C  CA    . LEU C 1 175 ? 80.036  105.350 142.002 1.00 103.54 ? 175 LEU B CA    1 
ATOM   4562 C  C     . LEU C 1 175 ? 79.925  106.786 142.505 1.00 103.49 ? 175 LEU B C     1 
ATOM   4563 O  O     . LEU C 1 175 ? 80.035  107.038 143.710 1.00 104.49 ? 175 LEU B O     1 
ATOM   4564 C  CB    . LEU C 1 175 ? 81.455  105.057 141.517 1.00 98.18  ? 175 LEU B CB    1 
ATOM   4565 C  CG    . LEU C 1 175 ? 82.050  103.726 141.976 1.00 89.70  ? 175 LEU B CG    1 
ATOM   4566 C  CD1   . LEU C 1 175 ? 83.489  103.587 141.511 1.00 83.15  ? 175 LEU B CD1   1 
ATOM   4567 C  CD2   . LEU C 1 175 ? 81.958  103.593 143.484 1.00 83.93  ? 175 LEU B CD2   1 
ATOM   4568 N  N     . ARG C 1 176 ? 79.706  107.739 141.594 1.00 106.37 ? 176 ARG B N     1 
ATOM   4569 C  CA    . ARG C 1 176 ? 79.635  109.148 141.965 1.00 107.77 ? 176 ARG B CA    1 
ATOM   4570 C  C     . ARG C 1 176 ? 78.441  109.459 142.856 1.00 109.15 ? 176 ARG B C     1 
ATOM   4571 O  O     . ARG C 1 176 ? 78.463  110.469 143.568 1.00 109.51 ? 176 ARG B O     1 
ATOM   4572 C  CB    . ARG C 1 176 ? 79.567  110.023 140.710 1.00 109.38 ? 176 ARG B CB    1 
ATOM   4573 C  CG    . ARG C 1 176 ? 80.879  110.173 139.952 1.00 109.21 ? 176 ARG B CG    1 
ATOM   4574 C  CD    . ARG C 1 176 ? 81.979  110.757 140.820 1.00 111.09 ? 176 ARG B CD    1 
ATOM   4575 N  NE    . ARG C 1 176 ? 81.501  111.838 141.674 1.00 116.09 ? 176 ARG B NE    1 
ATOM   4576 C  CZ    . ARG C 1 176 ? 82.280  112.767 142.211 1.00 114.21 ? 176 ARG B CZ    1 
ATOM   4577 N  NH1   . ARG C 1 176 ? 83.586  112.782 141.997 1.00 113.48 ? 176 ARG B NH1   1 
ATOM   4578 N  NH2   . ARG C 1 176 ? 81.736  113.704 142.981 1.00 110.48 ? 176 ARG B NH2   1 
ATOM   4579 N  N     . LYS C 1 177 ? 77.399  108.625 142.829 1.00 110.44 ? 177 LYS B N     1 
ATOM   4580 C  CA    . LYS C 1 177 ? 76.223  108.881 143.653 1.00 110.10 ? 177 LYS B CA    1 
ATOM   4581 C  C     . LYS C 1 177 ? 76.533  108.792 145.140 1.00 110.04 ? 177 LYS B C     1 
ATOM   4582 O  O     . LYS C 1 177 ? 75.791  109.355 145.952 1.00 110.72 ? 177 LYS B O     1 
ATOM   4583 C  CB    . LYS C 1 177 ? 75.105  107.902 143.294 1.00 110.70 ? 177 LYS B CB    1 
ATOM   4584 C  CG    . LYS C 1 177 ? 74.567  108.058 141.879 1.00 109.02 ? 177 LYS B CG    1 
ATOM   4585 C  CD    . LYS C 1 177 ? 74.187  109.501 141.578 1.00 112.19 ? 177 LYS B CD    1 
ATOM   4586 C  CE    . LYS C 1 177 ? 74.951  110.034 140.374 1.00 111.70 ? 177 LYS B CE    1 
ATOM   4587 N  NZ    . LYS C 1 177 ? 74.613  111.454 140.077 1.00 114.82 ? 177 LYS B NZ    1 
ATOM   4588 N  N     . ASP C 1 178 ? 77.605  108.097 145.514 1.00 111.43 ? 178 ASP B N     1 
ATOM   4589 C  CA    . ASP C 1 178 ? 78.035  107.991 146.901 1.00 110.99 ? 178 ASP B CA    1 
ATOM   4590 C  C     . ASP C 1 178 ? 79.199  108.918 147.223 1.00 106.50 ? 178 ASP B C     1 
ATOM   4591 O  O     . ASP C 1 178 ? 79.810  108.782 148.288 1.00 101.34 ? 178 ASP B O     1 
ATOM   4592 C  CB    . ASP C 1 178 ? 78.419  106.546 147.224 1.00 111.25 ? 178 ASP B CB    1 
ATOM   4593 C  CG    . ASP C 1 178 ? 77.349  105.554 146.818 1.00 120.61 ? 178 ASP B CG    1 
ATOM   4594 O  OD1   . ASP C 1 178 ? 76.333  105.978 146.230 1.00 116.87 ? 178 ASP B OD1   1 
ATOM   4595 O  OD2   . ASP C 1 178 ? 77.528  104.347 147.084 1.00 128.56 ? 178 ASP B OD2   1 
ATOM   4596 N  N     . GLY C 1 179 ? 79.519  109.852 146.335 1.00 106.50 ? 179 GLY B N     1 
ATOM   4597 C  CA    . GLY C 1 179 ? 80.670  110.714 146.537 1.00 98.94  ? 179 GLY B CA    1 
ATOM   4598 C  C     . GLY C 1 179 ? 81.994  109.984 146.479 1.00 101.33 ? 179 GLY B C     1 
ATOM   4599 O  O     . GLY C 1 179 ? 82.888  110.262 147.289 1.00 102.93 ? 179 GLY B O     1 
ATOM   4600 N  N     . LEU C 1 180 ? 82.140  109.054 145.543 1.00 105.09 ? 180 LEU B N     1 
ATOM   4601 C  CA    . LEU C 1 180 ? 83.361  108.285 145.343 1.00 97.75  ? 180 LEU B CA    1 
ATOM   4602 C  C     . LEU C 1 180 ? 83.895  108.548 143.936 1.00 98.19  ? 180 LEU B C     1 
ATOM   4603 O  O     . LEU C 1 180 ? 83.409  109.426 143.220 1.00 103.20 ? 180 LEU B O     1 
ATOM   4604 C  CB    . LEU C 1 180 ? 83.104  106.797 145.584 1.00 95.08  ? 180 LEU B CB    1 
ATOM   4605 C  CG    . LEU C 1 180 ? 83.357  106.301 147.006 1.00 90.43  ? 180 LEU B CG    1 
ATOM   4606 C  CD1   . LEU C 1 180 ? 82.114  106.476 147.855 1.00 94.99  ? 180 LEU B CD1   1 
ATOM   4607 C  CD2   . LEU C 1 180 ? 83.799  104.850 146.993 1.00 91.23  ? 180 LEU B CD2   1 
ATOM   4608 N  N     . GLY C 1 181 ? 84.912  107.788 143.548 1.00 91.45  ? 181 GLY B N     1 
ATOM   4609 C  CA    . GLY C 1 181 ? 85.463  107.927 142.213 1.00 87.28  ? 181 GLY B CA    1 
ATOM   4610 C  C     . GLY C 1 181 ? 86.470  106.835 141.936 1.00 82.57  ? 181 GLY B C     1 
ATOM   4611 O  O     . GLY C 1 181 ? 86.746  105.981 142.781 1.00 83.66  ? 181 GLY B O     1 
ATOM   4612 N  N     . LEU C 1 182 ? 87.018  106.874 140.724 1.00 80.29  ? 182 LEU B N     1 
ATOM   4613 C  CA    . LEU C 1 182 ? 88.042  105.929 140.280 1.00 79.40  ? 182 LEU B CA    1 
ATOM   4614 C  C     . LEU C 1 182 ? 89.184  106.698 139.628 1.00 78.30  ? 182 LEU B C     1 
ATOM   4615 O  O     . LEU C 1 182 ? 89.400  106.604 138.414 1.00 77.92  ? 182 LEU B O     1 
ATOM   4616 C  CB    . LEU C 1 182 ? 87.455  104.900 139.314 1.00 76.87  ? 182 LEU B CB    1 
ATOM   4617 C  CG    . LEU C 1 182 ? 87.008  103.573 139.925 1.00 79.03  ? 182 LEU B CG    1 
ATOM   4618 C  CD1   . LEU C 1 182 ? 86.395  102.681 138.861 1.00 81.68  ? 182 LEU B CD1   1 
ATOM   4619 C  CD2   . LEU C 1 182 ? 88.176  102.879 140.605 1.00 78.77  ? 182 LEU B CD2   1 
ATOM   4620 N  N     . PRO C 1 183 ? 89.939  107.470 140.407 1.00 71.89  ? 183 PRO B N     1 
ATOM   4621 C  CA    . PRO C 1 183 ? 91.034  108.246 139.822 1.00 68.12  ? 183 PRO B CA    1 
ATOM   4622 C  C     . PRO C 1 183 ? 92.194  107.354 139.418 1.00 71.31  ? 183 PRO B C     1 
ATOM   4623 O  O     . PRO C 1 183 ? 92.447  106.309 140.022 1.00 74.98  ? 183 PRO B O     1 
ATOM   4624 C  CB    . PRO C 1 183 ? 91.432  109.196 140.953 1.00 72.01  ? 183 PRO B CB    1 
ATOM   4625 C  CG    . PRO C 1 183 ? 91.108  108.438 142.187 1.00 72.80  ? 183 PRO B CG    1 
ATOM   4626 C  CD    . PRO C 1 183 ? 89.897  107.599 141.874 1.00 72.25  ? 183 PRO B CD    1 
ATOM   4627 N  N     . THR C 1 184 ? 92.907  107.786 138.381 1.00 73.22  ? 184 THR B N     1 
ATOM   4628 C  CA    . THR C 1 184 ? 94.078  107.065 137.906 1.00 71.74  ? 184 THR B CA    1 
ATOM   4629 C  C     . THR C 1 184 ? 94.899  107.985 137.018 1.00 71.65  ? 184 THR B C     1 
ATOM   4630 O  O     . THR C 1 184 ? 94.377  108.943 136.443 1.00 77.99  ? 184 THR B O     1 
ATOM   4631 C  CB    . THR C 1 184 ? 93.694  105.797 137.135 1.00 73.96  ? 184 THR B CB    1 
ATOM   4632 O  OG1   . THR C 1 184 ? 94.879  105.074 136.783 1.00 71.70  ? 184 THR B OG1   1 
ATOM   4633 C  CG2   . THR C 1 184 ? 92.931  106.150 135.869 1.00 69.60  ? 184 THR B CG2   1 
ATOM   4634 N  N     . SER C 1 185 ? 96.190  107.687 136.922 1.00 70.10  ? 185 SER B N     1 
ATOM   4635 C  CA    . SER C 1 185 ? 97.068  108.377 135.992 1.00 75.65  ? 185 SER B CA    1 
ATOM   4636 C  C     . SER C 1 185 ? 97.062  107.645 134.658 1.00 77.77  ? 185 SER B C     1 
ATOM   4637 O  O     . SER C 1 185 ? 97.109  106.412 134.614 1.00 85.62  ? 185 SER B O     1 
ATOM   4638 C  CB    . SER C 1 185 ? 98.490  108.461 136.544 1.00 75.56  ? 185 SER B CB    1 
ATOM   4639 O  OG    . SER C 1 185 ? 98.637  109.576 137.404 1.00 75.06  ? 185 SER B OG    1 
ATOM   4640 N  N     . THR C 1 186 ? 96.990  108.406 133.578 1.00 71.14  ? 186 THR B N     1 
ATOM   4641 C  CA    . THR C 1 186 ? 96.921  107.807 132.252 1.00 70.11  ? 186 THR B CA    1 
ATOM   4642 C  C     . THR C 1 186 ? 98.214  107.060 131.950 1.00 71.36  ? 186 THR B C     1 
ATOM   4643 O  O     . THR C 1 186 ? 99.302  107.601 132.178 1.00 77.01  ? 186 THR B O     1 
ATOM   4644 C  CB    . THR C 1 186 ? 96.682  108.877 131.193 1.00 75.49  ? 186 THR B CB    1 
ATOM   4645 O  OG1   . THR C 1 186 ? 97.878  109.642 131.010 1.00 75.75  ? 186 THR B OG1   1 
ATOM   4646 C  CG2   . THR C 1 186 ? 95.567  109.801 131.628 1.00 82.95  ? 186 THR B CG2   1 
ATOM   4647 N  N     . PRO C 1 187 ? 98.143  105.824 131.458 1.00 68.29  ? 187 PRO B N     1 
ATOM   4648 C  CA    . PRO C 1 187 ? 99.366  105.140 131.026 1.00 65.15  ? 187 PRO B CA    1 
ATOM   4649 C  C     . PRO C 1 187 ? 100.057 105.932 129.927 1.00 59.46  ? 187 PRO B C     1 
ATOM   4650 O  O     . PRO C 1 187 ? 99.412  106.506 129.049 1.00 65.86  ? 187 PRO B O     1 
ATOM   4651 C  CB    . PRO C 1 187 ? 98.859  103.784 130.521 1.00 66.59  ? 187 PRO B CB    1 
ATOM   4652 C  CG    . PRO C 1 187 ? 97.404  103.980 130.270 1.00 72.88  ? 187 PRO B CG    1 
ATOM   4653 C  CD    . PRO C 1 187 ? 96.947  104.990 131.271 1.00 73.02  ? 187 PRO B CD    1 
ATOM   4654 N  N     . ASP C 1 188 ? 101.388 105.952 129.982 1.00 50.17  ? 188 ASP B N     1 
ATOM   4655 C  CA    . ASP C 1 188 ? 102.160 106.864 129.149 1.00 51.62  ? 188 ASP B CA    1 
ATOM   4656 C  C     . ASP C 1 188 ? 102.132 106.506 127.672 1.00 55.44  ? 188 ASP B C     1 
ATOM   4657 O  O     . ASP C 1 188 ? 102.599 107.308 126.858 1.00 61.95  ? 188 ASP B O     1 
ATOM   4658 C  CB    . ASP C 1 188 ? 103.603 106.913 129.643 1.00 56.51  ? 188 ASP B CB    1 
ATOM   4659 C  CG    . ASP C 1 188 ? 103.749 107.717 130.915 1.00 58.82  ? 188 ASP B CG    1 
ATOM   4660 O  OD1   . ASP C 1 188 ? 102.795 108.436 131.274 1.00 60.07  ? 188 ASP B OD1   1 
ATOM   4661 O  OD2   . ASP C 1 188 ? 104.810 107.617 131.564 1.00 60.61  ? 188 ASP B OD2   1 
ATOM   4662 N  N     . LEU C 1 189 ? 101.611 105.339 127.302 1.00 50.66  ? 189 LEU B N     1 
ATOM   4663 C  CA    . LEU C 1 189 ? 101.487 104.996 125.892 1.00 52.28  ? 189 LEU B CA    1 
ATOM   4664 C  C     . LEU C 1 189 ? 100.507 103.844 125.740 1.00 58.44  ? 189 LEU B C     1 
ATOM   4665 O  O     . LEU C 1 189 ? 100.459 102.952 126.589 1.00 65.66  ? 189 LEU B O     1 
ATOM   4666 C  CB    . LEU C 1 189 ? 102.844 104.618 125.291 1.00 49.38  ? 189 LEU B CB    1 
ATOM   4667 C  CG    . LEU C 1 189 ? 102.923 104.618 123.767 1.00 49.12  ? 189 LEU B CG    1 
ATOM   4668 C  CD1   . LEU C 1 189 ? 104.282 105.100 123.327 1.00 52.88  ? 189 LEU B CD1   1 
ATOM   4669 C  CD2   . LEU C 1 189 ? 102.650 103.234 123.222 1.00 55.06  ? 189 LEU B CD2   1 
ATOM   4670 N  N     . ALA C 1 190 ? 99.747  103.858 124.646 1.00 62.01  ? 190 ALA B N     1 
ATOM   4671 C  CA    . ALA C 1 190 ? 98.781  102.804 124.359 1.00 60.76  ? 190 ALA B CA    1 
ATOM   4672 C  C     . ALA C 1 190 ? 99.003  102.287 122.946 1.00 66.88  ? 190 ALA B C     1 
ATOM   4673 O  O     . ALA C 1 190 ? 98.959  103.060 121.984 1.00 70.30  ? 190 ALA B O     1 
ATOM   4674 C  CB    . ALA C 1 190 ? 97.347  103.310 124.527 1.00 62.56  ? 190 ALA B CB    1 
ATOM   4675 N  N     . VAL C 1 191 ? 99.233  100.986 122.821 1.00 69.68  ? 191 VAL B N     1 
ATOM   4676 C  CA    . VAL C 1 191 ? 99.386  100.324 121.532 1.00 72.61  ? 191 VAL B CA    1 
ATOM   4677 C  C     . VAL C 1 191 ? 98.086  99.582  121.261 1.00 81.65  ? 191 VAL B C     1 
ATOM   4678 O  O     . VAL C 1 191 ? 97.736  98.643  121.984 1.00 85.29  ? 191 VAL B O     1 
ATOM   4679 C  CB    . VAL C 1 191 ? 100.589 99.373  121.532 1.00 70.66  ? 191 VAL B CB    1 
ATOM   4680 C  CG1   . VAL C 1 191 ? 100.484 98.379  120.397 1.00 77.43  ? 191 VAL B CG1   1 
ATOM   4681 C  CG2   . VAL C 1 191 ? 101.884 100.154 121.441 1.00 69.69  ? 191 VAL B CG2   1 
ATOM   4682 N  N     . VAL C 1 192 ? 97.358  100.000 120.225 1.00 81.49  ? 192 VAL B N     1 
ATOM   4683 C  CA    . VAL C 1 192 ? 96.034  99.466  119.936 1.00 80.40  ? 192 VAL B CA    1 
ATOM   4684 C  C     . VAL C 1 192 ? 96.005  98.955  118.502 1.00 85.56  ? 192 VAL B C     1 
ATOM   4685 O  O     . VAL C 1 192 ? 96.893  99.233  117.698 1.00 89.41  ? 192 VAL B O     1 
ATOM   4686 C  CB    . VAL C 1 192 ? 94.920  100.509 120.158 1.00 82.29  ? 192 VAL B CB    1 
ATOM   4687 C  CG1   . VAL C 1 192 ? 95.109  101.220 121.485 1.00 84.34  ? 192 VAL B CG1   1 
ATOM   4688 C  CG2   . VAL C 1 192 ? 94.902  101.508 119.021 1.00 79.74  ? 192 VAL B CG2   1 
ATOM   4689 N  N     . VAL C 1 193 ? 94.970  98.185  118.192 1.00 87.69  ? 193 VAL B N     1 
ATOM   4690 C  CA    . VAL C 1 193 ? 94.764  97.666  116.846 1.00 88.11  ? 193 VAL B CA    1 
ATOM   4691 C  C     . VAL C 1 193 ? 94.047  98.728  116.026 1.00 93.45  ? 193 VAL B C     1 
ATOM   4692 O  O     . VAL C 1 193 ? 93.052  99.307  116.478 1.00 98.33  ? 193 VAL B O     1 
ATOM   4693 C  CB    . VAL C 1 193 ? 93.968  96.351  116.877 1.00 87.67  ? 193 VAL B CB    1 
ATOM   4694 C  CG1   . VAL C 1 193 ? 93.258  96.123  115.553 1.00 88.11  ? 193 VAL B CG1   1 
ATOM   4695 C  CG2   . VAL C 1 193 ? 94.888  95.186  117.195 1.00 85.77  ? 193 VAL B CG2   1 
ATOM   4696 N  N     . LEU C 1 194 ? 94.562  98.997  114.831 1.00 90.73  ? 194 LEU B N     1 
ATOM   4697 C  CA    . LEU C 1 194 ? 94.007  100.051 113.995 1.00 95.24  ? 194 LEU B CA    1 
ATOM   4698 C  C     . LEU C 1 194 ? 92.558  99.734  113.635 1.00 101.36 ? 194 LEU B C     1 
ATOM   4699 O  O     . LEU C 1 194 ? 92.255  98.595  113.251 1.00 103.60 ? 194 LEU B O     1 
ATOM   4700 C  CB    . LEU C 1 194 ? 94.841  100.215 112.726 1.00 91.67  ? 194 LEU B CB    1 
ATOM   4701 C  CG    . LEU C 1 194 ? 94.788  101.582 112.044 1.00 94.34  ? 194 LEU B CG    1 
ATOM   4702 C  CD1   . LEU C 1 194 ? 95.109  102.683 113.033 1.00 92.18  ? 194 LEU B CD1   1 
ATOM   4703 C  CD2   . LEU C 1 194 ? 95.743  101.628 110.868 1.00 95.71  ? 194 LEU B CD2   1 
ATOM   4704 N  N     . PRO C 1 195 ? 91.641  100.694 113.751 1.00 100.87 ? 195 PRO B N     1 
ATOM   4705 C  CA    . PRO C 1 195 ? 90.247  100.437 113.375 1.00 108.84 ? 195 PRO B CA    1 
ATOM   4706 C  C     . PRO C 1 195 ? 90.113  100.138 111.888 1.00 114.85 ? 195 PRO B C     1 
ATOM   4707 O  O     . PRO C 1 195 ? 91.020  100.377 111.090 1.00 116.19 ? 195 PRO B O     1 
ATOM   4708 C  CB    . PRO C 1 195 ? 89.530  101.740 113.749 1.00 107.92 ? 195 PRO B CB    1 
ATOM   4709 C  CG    . PRO C 1 195 ? 90.419  102.392 114.753 1.00 97.48  ? 195 PRO B CG    1 
ATOM   4710 C  CD    . PRO C 1 195 ? 91.813  102.024 114.357 1.00 94.66  ? 195 PRO B CD    1 
ATOM   4711 N  N     . GLU C 1 196 ? 88.946  99.601  111.524 1.00 115.66 ? 196 GLU B N     1 
ATOM   4712 C  CA    . GLU C 1 196 ? 88.734  99.136  110.157 1.00 119.93 ? 196 GLU B CA    1 
ATOM   4713 C  C     . GLU C 1 196 ? 88.821  100.279 109.151 1.00 117.93 ? 196 GLU B C     1 
ATOM   4714 O  O     . GLU C 1 196 ? 89.435  100.132 108.088 1.00 119.14 ? 196 GLU B O     1 
ATOM   4715 C  CB    . GLU C 1 196 ? 87.381  98.432  110.050 1.00 122.55 ? 196 GLU B CB    1 
ATOM   4716 C  CG    . GLU C 1 196 ? 87.079  97.875  108.670 1.00 126.76 ? 196 GLU B CG    1 
ATOM   4717 C  CD    . GLU C 1 196 ? 87.421  96.402  108.551 1.00 129.45 ? 196 GLU B CD    1 
ATOM   4718 O  OE1   . GLU C 1 196 ? 87.889  95.817  109.551 1.00 127.78 ? 196 GLU B OE1   1 
ATOM   4719 O  OE2   . GLU C 1 196 ? 87.223  95.831  107.459 1.00 133.91 ? 196 GLU B OE2   1 
ATOM   4720 N  N     . GLU C 1 197 ? 88.220  101.425 109.467 1.00 114.17 ? 197 GLU B N     1 
ATOM   4721 C  CA    . GLU C 1 197 ? 88.160  102.526 108.514 1.00 117.85 ? 197 GLU B CA    1 
ATOM   4722 C  C     . GLU C 1 197 ? 89.463  103.307 108.410 1.00 115.46 ? 197 GLU B C     1 
ATOM   4723 O  O     . GLU C 1 197 ? 89.584  104.157 107.522 1.00 116.16 ? 197 GLU B O     1 
ATOM   4724 C  CB    . GLU C 1 197 ? 87.024  103.482 108.883 1.00 119.90 ? 197 GLU B CB    1 
ATOM   4725 C  CG    . GLU C 1 197 ? 87.248  104.244 110.174 1.00 117.07 ? 197 GLU B CG    1 
ATOM   4726 C  CD    . GLU C 1 197 ? 86.413  103.703 111.315 1.00 118.48 ? 197 GLU B CD    1 
ATOM   4727 O  OE1   . GLU C 1 197 ? 86.475  102.482 111.569 1.00 118.76 ? 197 GLU B OE1   1 
ATOM   4728 O  OE2   . GLU C 1 197 ? 85.692  104.496 111.954 1.00 117.14 ? 197 GLU B OE2   1 
ATOM   4729 N  N     . PHE C 1 198 ? 90.432  103.049 109.285 1.00 113.93 ? 198 PHE B N     1 
ATOM   4730 C  CA    . PHE C 1 198 ? 91.707  103.749 109.264 1.00 114.23 ? 198 PHE B CA    1 
ATOM   4731 C  C     . PHE C 1 198 ? 92.806  102.948 108.580 1.00 118.14 ? 198 PHE B C     1 
ATOM   4732 O  O     . PHE C 1 198 ? 93.960  103.388 108.565 1.00 117.60 ? 198 PHE B O     1 
ATOM   4733 C  CB    . PHE C 1 198 ? 92.134  104.108 110.689 1.00 108.89 ? 198 PHE B CB    1 
ATOM   4734 C  CG    . PHE C 1 198 ? 91.517  105.374 111.208 1.00 108.14 ? 198 PHE B CG    1 
ATOM   4735 C  CD1   . PHE C 1 198 ? 90.431  105.946 110.570 1.00 110.67 ? 198 PHE B CD1   1 
ATOM   4736 C  CD2   . PHE C 1 198 ? 92.022  105.991 112.338 1.00 104.22 ? 198 PHE B CD2   1 
ATOM   4737 C  CE1   . PHE C 1 198 ? 89.862  107.109 111.048 1.00 106.28 ? 198 PHE B CE1   1 
ATOM   4738 C  CE2   . PHE C 1 198 ? 91.457  107.153 112.820 1.00 104.63 ? 198 PHE B CE2   1 
ATOM   4739 C  CZ    . PHE C 1 198 ? 90.376  107.713 112.174 1.00 102.64 ? 198 PHE B CZ    1 
ATOM   4740 N  N     . GLN C 1 199 ? 92.478  101.791 108.012 1.00 115.93 ? 199 GLN B N     1 
ATOM   4741 C  CA    . GLN C 1 199 ? 93.484  100.907 107.437 1.00 110.18 ? 199 GLN B CA    1 
ATOM   4742 C  C     . GLN C 1 199 ? 93.876  101.287 106.015 1.00 115.75 ? 199 GLN B C     1 
ATOM   4743 O  O     . GLN C 1 199 ? 94.754  100.634 105.440 1.00 118.30 ? 199 GLN B O     1 
ATOM   4744 C  CB    . GLN C 1 199 ? 92.985  99.462  107.476 1.00 107.50 ? 199 GLN B CB    1 
ATOM   4745 C  CG    . GLN C 1 199 ? 92.838  98.919  108.885 1.00 106.05 ? 199 GLN B CG    1 
ATOM   4746 C  CD    . GLN C 1 199 ? 92.272  97.518  108.920 1.00 109.29 ? 199 GLN B CD    1 
ATOM   4747 O  OE1   . GLN C 1 199 ? 91.934  97.000  109.983 1.00 107.09 ? 199 GLN B OE1   1 
ATOM   4748 N  NE2   . GLN C 1 199 ? 92.166  96.894  107.754 1.00 113.18 ? 199 GLN B NE2   1 
ATOM   4749 N  N     . ASN C 1 200 ? 93.256  102.314 105.435 1.00 118.94 ? 200 ASN B N     1 
ATOM   4750 C  CA    . ASN C 1 200 ? 93.662  102.828 104.137 1.00 120.38 ? 200 ASN B CA    1 
ATOM   4751 C  C     . ASN C 1 200 ? 94.393  104.159 104.223 1.00 120.29 ? 200 ASN B C     1 
ATOM   4752 O  O     . ASN C 1 200 ? 94.863  104.655 103.193 1.00 121.41 ? 200 ASN B O     1 
ATOM   4753 C  CB    . ASN C 1 200 ? 92.443  102.981 103.214 1.00 119.62 ? 200 ASN B CB    1 
ATOM   4754 C  CG    . ASN C 1 200 ? 91.340  101.994 103.538 1.00 118.46 ? 200 ASN B CG    1 
ATOM   4755 O  OD1   . ASN C 1 200 ? 91.540  100.781 103.481 1.00 119.42 ? 200 ASN B OD1   1 
ATOM   4756 N  ND2   . ASN C 1 200 ? 90.165  102.511 103.876 1.00 116.46 ? 200 ASN B ND2   1 
ATOM   4757 N  N     . ASP C 1 201 ? 94.499  104.747 105.412 1.00 117.22 ? 201 ASP B N     1 
ATOM   4758 C  CA    . ASP C 1 201 ? 95.190  106.019 105.564 1.00 118.00 ? 201 ASP B CA    1 
ATOM   4759 C  C     . ASP C 1 201 ? 96.693  105.837 105.395 1.00 114.71 ? 201 ASP B C     1 
ATOM   4760 O  O     . ASP C 1 201 ? 97.261  104.815 105.788 1.00 111.44 ? 201 ASP B O     1 
ATOM   4761 C  CB    . ASP C 1 201 ? 94.886  106.629 106.930 1.00 117.46 ? 201 ASP B CB    1 
ATOM   4762 C  CG    . ASP C 1 201 ? 93.719  107.596 106.889 1.00 123.33 ? 201 ASP B CG    1 
ATOM   4763 O  OD1   . ASP C 1 201 ? 92.699  107.273 106.245 1.00 122.29 ? 201 ASP B OD1   1 
ATOM   4764 O  OD2   . ASP C 1 201 ? 93.823  108.680 107.500 1.00 125.64 ? 201 ASP B OD2   1 
ATOM   4765 N  N     . GLU C 1 202 ? 97.336  106.840 104.804 1.00 115.32 ? 202 GLU B N     1 
ATOM   4766 C  CA    . GLU C 1 202 ? 98.774  106.816 104.580 1.00 114.27 ? 202 GLU B CA    1 
ATOM   4767 C  C     . GLU C 1 202 ? 99.561  107.507 105.684 1.00 108.16 ? 202 GLU B C     1 
ATOM   4768 O  O     . GLU C 1 202 ? 100.789 107.582 105.592 1.00 108.20 ? 202 GLU B O     1 
ATOM   4769 C  CB    . GLU C 1 202 ? 99.112  107.462 103.232 1.00 119.03 ? 202 GLU B CB    1 
ATOM   4770 C  CG    . GLU C 1 202 ? 98.192  107.053 102.094 1.00 124.46 ? 202 GLU B CG    1 
ATOM   4771 C  CD    . GLU C 1 202 ? 98.950  106.730 100.821 1.00 133.44 ? 202 GLU B CD    1 
ATOM   4772 O  OE1   . GLU C 1 202 ? 99.894  107.475 100.485 1.00 136.48 ? 202 GLU B OE1   1 
ATOM   4773 O  OE2   . GLU C 1 202 ? 98.601  105.732 100.157 1.00 133.83 ? 202 GLU B OE2   1 
ATOM   4774 N  N     . MET C 1 203 ? 98.892  108.015 106.719 1.00 103.79 ? 203 MET B N     1 
ATOM   4775 C  CA    . MET C 1 203 ? 99.593  108.669 107.816 1.00 102.19 ? 203 MET B CA    1 
ATOM   4776 C  C     . MET C 1 203 ? 100.122 107.685 108.850 1.00 101.12 ? 203 MET B C     1 
ATOM   4777 O  O     . MET C 1 203 ? 100.964 108.067 109.669 1.00 100.32 ? 203 MET B O     1 
ATOM   4778 C  CB    . MET C 1 203 ? 98.676  109.691 108.492 1.00 98.00  ? 203 MET B CB    1 
ATOM   4779 C  CG    . MET C 1 203 ? 97.878  109.147 109.663 1.00 97.50  ? 203 MET B CG    1 
ATOM   4780 S  SD    . MET C 1 203 ? 98.631  109.546 111.250 1.00 96.92  ? 203 MET B SD    1 
ATOM   4781 C  CE    . MET C 1 203 ? 98.124  111.251 111.438 1.00 92.06  ? 203 MET B CE    1 
ATOM   4782 N  N     . TRP C 1 204 ? 99.660  106.436 108.830 1.00 99.86  ? 204 TRP B N     1 
ATOM   4783 C  CA    . TRP C 1 204 ? 100.142 105.404 109.736 1.00 96.99  ? 204 TRP B CA    1 
ATOM   4784 C  C     . TRP C 1 204 ? 101.175 104.498 109.080 1.00 98.00  ? 204 TRP B C     1 
ATOM   4785 O  O     . TRP C 1 204 ? 101.480 103.427 109.615 1.00 97.74  ? 204 TRP B O     1 
ATOM   4786 C  CB    . TRP C 1 204 ? 98.972  104.573 110.264 1.00 93.07  ? 204 TRP B CB    1 
ATOM   4787 C  CG    . TRP C 1 204 ? 97.830  105.396 110.767 1.00 96.88  ? 204 TRP B CG    1 
ATOM   4788 C  CD1   . TRP C 1 204 ? 96.745  105.813 110.056 1.00 102.89 ? 204 TRP B CD1   1 
ATOM   4789 C  CD2   . TRP C 1 204 ? 97.660  105.906 112.094 1.00 96.93  ? 204 TRP B CD2   1 
ATOM   4790 N  NE1   . TRP C 1 204 ? 95.909  106.552 110.856 1.00 102.65 ? 204 TRP B NE1   1 
ATOM   4791 C  CE2   . TRP C 1 204 ? 96.448  106.624 112.113 1.00 97.95  ? 204 TRP B CE2   1 
ATOM   4792 C  CE3   . TRP C 1 204 ? 98.414  105.826 113.268 1.00 96.09  ? 204 TRP B CE3   1 
ATOM   4793 C  CZ2   . TRP C 1 204 ? 95.975  107.257 113.259 1.00 92.15  ? 204 TRP B CZ2   1 
ATOM   4794 C  CZ3   . TRP C 1 204 ? 97.941  106.455 114.403 1.00 92.87  ? 204 TRP B CZ3   1 
ATOM   4795 C  CH2   . TRP C 1 204 ? 96.736  107.162 114.390 1.00 89.12  ? 204 TRP B CH2   1 
ATOM   4796 N  N     . ARG C 1 205 ? 101.716 104.902 107.930 1.00 97.33  ? 205 ARG B N     1 
ATOM   4797 C  CA    . ARG C 1 205 ? 102.648 104.068 107.188 1.00 96.30  ? 205 ARG B CA    1 
ATOM   4798 C  C     . ARG C 1 205 ? 103.929 104.782 106.780 1.00 96.23  ? 205 ARG B C     1 
ATOM   4799 O  O     . ARG C 1 205 ? 104.758 104.175 106.095 1.00 99.83  ? 205 ARG B O     1 
ATOM   4800 C  CB    . ARG C 1 205 ? 101.974 103.505 105.929 1.00 99.96  ? 205 ARG B CB    1 
ATOM   4801 C  CG    . ARG C 1 205 ? 100.715 102.714 106.206 1.00 98.87  ? 205 ARG B CG    1 
ATOM   4802 C  CD    . ARG C 1 205 ? 100.516 101.640 105.160 1.00 104.79 ? 205 ARG B CD    1 
ATOM   4803 N  NE    . ARG C 1 205 ? 100.445 102.197 103.815 1.00 114.42 ? 205 ARG B NE    1 
ATOM   4804 C  CZ    . ARG C 1 205 ? 99.317  102.421 103.156 1.00 116.01 ? 205 ARG B CZ    1 
ATOM   4805 N  NH1   . ARG C 1 205 ? 98.138  102.147 103.691 1.00 115.04 ? 205 ARG B NH1   1 
ATOM   4806 N  NH2   . ARG C 1 205 ? 99.372  102.933 101.930 1.00 116.35 ? 205 ARG B NH2   1 
ATOM   4807 N  N     . GLU C 1 206 ? 104.116 106.039 107.166 1.00 95.96  ? 206 GLU B N     1 
ATOM   4808 C  CA    . GLU C 1 206 ? 105.322 106.785 106.838 1.00 95.90  ? 206 GLU B CA    1 
ATOM   4809 C  C     . GLU C 1 206 ? 106.115 107.049 108.109 1.00 89.41  ? 206 GLU B C     1 
ATOM   4810 O  O     . GLU C 1 206 ? 105.585 107.612 109.072 1.00 86.10  ? 206 GLU B O     1 
ATOM   4811 C  CB    . GLU C 1 206 ? 104.987 108.106 106.140 1.00 101.95 ? 206 GLU B CB    1 
ATOM   4812 C  CG    . GLU C 1 206 ? 103.750 108.808 106.672 1.00 103.53 ? 206 GLU B CG    1 
ATOM   4813 C  CD    . GLU C 1 206 ? 103.048 109.630 105.609 1.00 107.74 ? 206 GLU B CD    1 
ATOM   4814 O  OE1   . GLU C 1 206 ? 103.457 109.553 104.431 1.00 111.96 ? 206 GLU B OE1   1 
ATOM   4815 O  OE2   . GLU C 1 206 ? 102.090 110.355 105.950 1.00 106.30 ? 206 GLU B OE2   1 
ATOM   4816 N  N     . GLU C 1 207 ? 107.379 106.637 108.108 1.00 84.01  ? 207 GLU B N     1 
ATOM   4817 C  CA    . GLU C 1 207 ? 108.251 106.893 109.244 1.00 77.15  ? 207 GLU B CA    1 
ATOM   4818 C  C     . GLU C 1 207 ? 108.611 108.372 109.301 1.00 77.18  ? 207 GLU B C     1 
ATOM   4819 O  O     . GLU C 1 207 ? 108.943 108.980 108.279 1.00 78.24  ? 207 GLU B O     1 
ATOM   4820 C  CB    . GLU C 1 207 ? 109.515 106.043 109.145 1.00 74.91  ? 207 GLU B CB    1 
ATOM   4821 C  CG    . GLU C 1 207 ? 109.286 104.558 109.364 1.00 77.08  ? 207 GLU B CG    1 
ATOM   4822 C  CD    . GLU C 1 207 ? 110.543 103.740 109.151 1.00 83.01  ? 207 GLU B CD    1 
ATOM   4823 O  OE1   . GLU C 1 207 ? 111.563 104.317 108.721 1.00 89.01  ? 207 GLU B OE1   1 
ATOM   4824 O  OE2   . GLU C 1 207 ? 110.513 102.520 109.413 1.00 81.29  ? 207 GLU B OE2   1 
ATOM   4825 N  N     . ILE C 1 208 ? 108.541 108.952 110.498 1.00 76.82  ? 208 ILE B N     1 
ATOM   4826 C  CA    . ILE C 1 208 ? 108.879 110.360 110.663 1.00 76.16  ? 208 ILE B CA    1 
ATOM   4827 C  C     . ILE C 1 208 ? 110.387 110.531 110.563 1.00 73.72  ? 208 ILE B C     1 
ATOM   4828 O  O     . ILE C 1 208 ? 111.158 109.761 111.150 1.00 72.14  ? 208 ILE B O     1 
ATOM   4829 C  CB    . ILE C 1 208 ? 108.341 110.893 111.999 1.00 69.84  ? 208 ILE B CB    1 
ATOM   4830 C  CG1   . ILE C 1 208 ? 108.685 109.934 113.139 1.00 63.99  ? 208 ILE B CG1   1 
ATOM   4831 C  CG2   . ILE C 1 208 ? 106.839 111.098 111.923 1.00 70.16  ? 208 ILE B CG2   1 
ATOM   4832 C  CD1   . ILE C 1 208 ? 108.250 110.432 114.495 1.00 56.60  ? 208 ILE B CD1   1 
ATOM   4833 N  N     . ALA C 1 209 ? 110.818 111.540 109.802 1.00 74.71  ? 209 ALA B N     1 
ATOM   4834 C  CA    . ALA C 1 209 ? 112.245 111.795 109.645 1.00 74.06  ? 209 ALA B CA    1 
ATOM   4835 C  C     . ALA C 1 209 ? 112.897 112.250 110.941 1.00 70.36  ? 209 ALA B C     1 
ATOM   4836 O  O     . ALA C 1 209 ? 114.101 112.042 111.121 1.00 70.27  ? 209 ALA B O     1 
ATOM   4837 C  CB    . ALA C 1 209 ? 112.478 112.838 108.553 1.00 74.05  ? 209 ALA B CB    1 
ATOM   4838 N  N     . GLY C 1 210 ? 112.137 112.860 111.840 1.00 64.84  ? 210 GLY B N     1 
ATOM   4839 C  CA    . GLY C 1 210 ? 112.681 113.306 113.108 1.00 63.02  ? 210 GLY B CA    1 
ATOM   4840 C  C     . GLY C 1 210 ? 111.573 113.859 113.971 1.00 60.97  ? 210 GLY B C     1 
ATOM   4841 O  O     . GLY C 1 210 ? 110.405 113.900 113.574 1.00 67.96  ? 210 GLY B O     1 
ATOM   4842 N  N     . LEU C 1 211 ? 111.955 114.287 115.172 1.00 54.37  ? 211 LEU B N     1 
ATOM   4843 C  CA    . LEU C 1 211 ? 110.994 114.845 116.121 1.00 57.76  ? 211 LEU B CA    1 
ATOM   4844 C  C     . LEU C 1 211 ? 110.940 116.369 115.999 1.00 58.17  ? 211 LEU B C     1 
ATOM   4845 O  O     . LEU C 1 211 ? 111.150 117.111 116.957 1.00 54.22  ? 211 LEU B O     1 
ATOM   4846 C  CB    . LEU C 1 211 ? 111.341 114.416 117.541 1.00 53.59  ? 211 LEU B CB    1 
ATOM   4847 C  CG    . LEU C 1 211 ? 110.549 113.242 118.111 1.00 47.59  ? 211 LEU B CG    1 
ATOM   4848 C  CD1   . LEU C 1 211 ? 111.310 112.602 119.254 1.00 46.72  ? 211 LEU B CD1   1 
ATOM   4849 C  CD2   . LEU C 1 211 ? 109.179 113.694 118.567 1.00 50.90  ? 211 LEU B CD2   1 
ATOM   4850 N  N     . THR C 1 212 ? 110.642 116.829 114.788 1.00 61.58  ? 212 THR B N     1 
ATOM   4851 C  CA    . THR C 1 212 ? 110.419 118.248 114.575 1.00 62.03  ? 212 THR B CA    1 
ATOM   4852 C  C     . THR C 1 212 ? 109.097 118.666 115.211 1.00 64.57  ? 212 THR B C     1 
ATOM   4853 O  O     . THR C 1 212 ? 108.287 117.835 115.627 1.00 68.01  ? 212 THR B O     1 
ATOM   4854 C  CB    . THR C 1 212 ? 110.423 118.578 113.084 1.00 63.79  ? 212 THR B CB    1 
ATOM   4855 O  OG1   . THR C 1 212 ? 109.750 117.541 112.361 1.00 63.15  ? 212 THR B OG1   1 
ATOM   4856 C  CG2   . THR C 1 212 ? 111.847 118.702 112.571 1.00 65.48  ? 212 THR B CG2   1 
ATOM   4857 N  N     . ARG C 1 213 ? 108.881 119.977 115.284 1.00 67.62  ? 213 ARG B N     1 
ATOM   4858 C  CA    . ARG C 1 213 ? 107.667 120.485 115.920 1.00 69.96  ? 213 ARG B CA    1 
ATOM   4859 C  C     . ARG C 1 213 ? 106.393 119.996 115.239 1.00 74.19  ? 213 ARG B C     1 
ATOM   4860 O  O     . ARG C 1 213 ? 105.475 119.550 115.951 1.00 77.66  ? 213 ARG B O     1 
ATOM   4861 C  CB    . ARG C 1 213 ? 107.723 122.014 115.987 1.00 73.06  ? 213 ARG B CB    1 
ATOM   4862 C  CG    . ARG C 1 213 ? 106.540 122.641 116.694 1.00 76.70  ? 213 ARG B CG    1 
ATOM   4863 C  CD    . ARG C 1 213 ? 106.750 122.660 118.195 1.00 79.60  ? 213 ARG B CD    1 
ATOM   4864 N  NE    . ARG C 1 213 ? 105.765 121.844 118.894 1.00 83.57  ? 213 ARG B NE    1 
ATOM   4865 C  CZ    . ARG C 1 213 ? 105.425 122.010 120.164 1.00 87.40  ? 213 ARG B CZ    1 
ATOM   4866 N  NH1   . ARG C 1 213 ? 105.968 122.962 120.906 1.00 91.40  ? 213 ARG B NH1   1 
ATOM   4867 N  NH2   . ARG C 1 213 ? 104.520 121.201 120.706 1.00 81.46  ? 213 ARG B NH2   1 
ATOM   4868 N  N     . PRO C 1 214 ? 106.253 120.044 113.907 1.00 73.01  ? 214 PRO B N     1 
ATOM   4869 C  CA    . PRO C 1 214 ? 105.068 119.416 113.297 1.00 70.77  ? 214 PRO B CA    1 
ATOM   4870 C  C     . PRO C 1 214 ? 104.957 117.935 113.605 1.00 70.37  ? 214 PRO B C     1 
ATOM   4871 O  O     . PRO C 1 214 ? 103.848 117.429 113.817 1.00 67.93  ? 214 PRO B O     1 
ATOM   4872 C  CB    . PRO C 1 214 ? 105.269 119.674 111.797 1.00 69.73  ? 214 PRO B CB    1 
ATOM   4873 C  CG    . PRO C 1 214 ? 106.140 120.868 111.736 1.00 70.25  ? 214 PRO B CG    1 
ATOM   4874 C  CD    . PRO C 1 214 ? 107.073 120.738 112.896 1.00 69.85  ? 214 PRO B CD    1 
ATOM   4875 N  N     . ASN C 1 215 ? 106.084 117.223 113.659 1.00 67.88  ? 215 ASN B N     1 
ATOM   4876 C  CA    . ASN C 1 215 ? 106.036 115.806 113.998 1.00 64.00  ? 215 ASN B CA    1 
ATOM   4877 C  C     . ASN C 1 215 ? 105.681 115.594 115.463 1.00 65.12  ? 215 ASN B C     1 
ATOM   4878 O  O     . ASN C 1 215 ? 105.002 114.618 115.798 1.00 64.82  ? 215 ASN B O     1 
ATOM   4879 C  CB    . ASN C 1 215 ? 107.368 115.141 113.665 1.00 63.60  ? 215 ASN B CB    1 
ATOM   4880 C  CG    . ASN C 1 215 ? 107.572 114.970 112.176 1.00 70.40  ? 215 ASN B CG    1 
ATOM   4881 O  OD1   . ASN C 1 215 ? 106.742 114.378 111.489 1.00 72.69  ? 215 ASN B OD1   1 
ATOM   4882 N  ND2   . ASN C 1 215 ? 108.681 115.492 111.667 1.00 72.77  ? 215 ASN B ND2   1 
ATOM   4883 N  N     . GLN C 1 216 ? 106.122 116.490 116.348 1.00 69.38  ? 216 GLN B N     1 
ATOM   4884 C  CA    . GLN C 1 216 ? 105.686 116.415 117.739 1.00 66.45  ? 216 GLN B CA    1 
ATOM   4885 C  C     . GLN C 1 216 ? 104.181 116.610 117.848 1.00 71.71  ? 216 GLN B C     1 
ATOM   4886 O  O     . GLN C 1 216 ? 103.513 115.913 118.620 1.00 77.01  ? 216 GLN B O     1 
ATOM   4887 C  CB    . GLN C 1 216 ? 106.416 117.456 118.587 1.00 69.34  ? 216 GLN B CB    1 
ATOM   4888 C  CG    . GLN C 1 216 ? 107.912 117.254 118.690 1.00 67.81  ? 216 GLN B CG    1 
ATOM   4889 C  CD    . GLN C 1 216 ? 108.522 118.067 119.807 1.00 66.74  ? 216 GLN B CD    1 
ATOM   4890 O  OE1   . GLN C 1 216 ? 107.975 118.138 120.905 1.00 67.89  ? 216 GLN B OE1   1 
ATOM   4891 N  NE2   . GLN C 1 216 ? 109.658 118.694 119.532 1.00 63.33  ? 216 GLN B NE2   1 
ATOM   4892 N  N     . ILE C 1 217 ? 103.628 117.556 117.085 1.00 71.94  ? 217 ILE B N     1 
ATOM   4893 C  CA    . ILE C 1 217 ? 102.180 117.755 117.088 1.00 70.78  ? 217 ILE B CA    1 
ATOM   4894 C  C     . ILE C 1 217 ? 101.470 116.519 116.551 1.00 75.30  ? 217 ILE B C     1 
ATOM   4895 O  O     . ILE C 1 217 ? 100.436 116.097 117.084 1.00 76.00  ? 217 ILE B O     1 
ATOM   4896 C  CB    . ILE C 1 217 ? 101.805 119.014 116.286 1.00 70.25  ? 217 ILE B CB    1 
ATOM   4897 C  CG1   . ILE C 1 217 ? 102.517 120.243 116.850 1.00 76.04  ? 217 ILE B CG1   1 
ATOM   4898 C  CG2   . ILE C 1 217 ? 100.302 119.224 116.303 1.00 67.77  ? 217 ILE B CG2   1 
ATOM   4899 C  CD1   . ILE C 1 217 ? 102.392 120.385 118.346 1.00 74.67  ? 217 ILE B CD1   1 
ATOM   4900 N  N     . LEU C 1 218 ? 102.006 115.927 115.482 1.00 75.16  ? 218 LEU B N     1 
ATOM   4901 C  CA    . LEU C 1 218 ? 101.387 114.740 114.900 1.00 71.60  ? 218 LEU B CA    1 
ATOM   4902 C  C     . LEU C 1 218 ? 101.387 113.573 115.880 1.00 72.07  ? 218 LEU B C     1 
ATOM   4903 O  O     . LEU C 1 218 ? 100.379 112.871 116.019 1.00 72.97  ? 218 LEU B O     1 
ATOM   4904 C  CB    . LEU C 1 218 ? 102.107 114.359 113.607 1.00 71.16  ? 218 LEU B CB    1 
ATOM   4905 C  CG    . LEU C 1 218 ? 101.638 113.098 112.882 1.00 69.78  ? 218 LEU B CG    1 
ATOM   4906 C  CD1   . LEU C 1 218 ? 101.422 113.387 111.409 1.00 70.18  ? 218 LEU B CD1   1 
ATOM   4907 C  CD2   . LEU C 1 218 ? 102.644 111.979 113.056 1.00 69.00  ? 218 LEU B CD2   1 
ATOM   4908 N  N     . LEU C 1 219 ? 102.510 113.349 116.567 1.00 71.08  ? 219 LEU B N     1 
ATOM   4909 C  CA    . LEU C 1 219 ? 102.587 112.244 117.519 1.00 70.47  ? 219 LEU B CA    1 
ATOM   4910 C  C     . LEU C 1 219 ? 101.709 112.494 118.739 1.00 69.77  ? 219 LEU B C     1 
ATOM   4911 O  O     . LEU C 1 219 ? 100.989 111.594 119.186 1.00 72.87  ? 219 LEU B O     1 
ATOM   4912 C  CB    . LEU C 1 219 ? 104.034 112.018 117.951 1.00 66.06  ? 219 LEU B CB    1 
ATOM   4913 C  CG    . LEU C 1 219 ? 105.027 111.522 116.901 1.00 69.72  ? 219 LEU B CG    1 
ATOM   4914 C  CD1   . LEU C 1 219 ? 106.255 110.940 117.577 1.00 60.48  ? 219 LEU B CD1   1 
ATOM   4915 C  CD2   . LEU C 1 219 ? 104.383 110.501 115.991 1.00 65.76  ? 219 LEU B CD2   1 
ATOM   4916 N  N     . SER C 1 220 ? 101.760 113.706 119.296 1.00 68.88  ? 220 SER B N     1 
ATOM   4917 C  CA    . SER C 1 220 ? 101.005 113.998 120.509 1.00 70.32  ? 220 SER B CA    1 
ATOM   4918 C  C     . SER C 1 220 ? 99.504  113.925 120.264 1.00 74.51  ? 220 SER B C     1 
ATOM   4919 O  O     . SER C 1 220 ? 98.756  113.427 121.112 1.00 73.97  ? 220 SER B O     1 
ATOM   4920 C  CB    . SER C 1 220 ? 101.392 115.375 121.048 1.00 73.13  ? 220 SER B CB    1 
ATOM   4921 O  OG    . SER C 1 220 ? 102.788 115.460 121.272 1.00 80.29  ? 220 SER B OG    1 
ATOM   4922 N  N     . GLY C 1 221 ? 99.046  114.412 119.114 1.00 77.71  ? 221 GLY B N     1 
ATOM   4923 C  CA    . GLY C 1 221 ? 97.629  114.435 118.811 1.00 81.24  ? 221 GLY B CA    1 
ATOM   4924 C  C     . GLY C 1 221 ? 97.144  113.218 118.052 1.00 79.79  ? 221 GLY B C     1 
ATOM   4925 O  O     . GLY C 1 221 ? 96.063  113.242 117.457 1.00 83.43  ? 221 GLY B O     1 
ATOM   4926 N  N     . ALA C 1 222 ? 97.937  112.145 118.061 1.00 73.29  ? 222 ALA B N     1 
ATOM   4927 C  CA    . ALA C 1 222 ? 97.550  110.932 117.352 1.00 75.12  ? 222 ALA B CA    1 
ATOM   4928 C  C     . ALA C 1 222 ? 96.393  110.207 118.025 1.00 80.23  ? 222 ALA B C     1 
ATOM   4929 O  O     . ALA C 1 222 ? 95.727  109.395 117.374 1.00 84.22  ? 222 ALA B O     1 
ATOM   4930 C  CB    . ALA C 1 222 ? 98.747  109.990 117.226 1.00 72.51  ? 222 ALA B CB    1 
ATOM   4931 N  N     . TYR C 1 223 ? 96.141  110.470 119.307 1.00 78.16  ? 223 TYR B N     1 
ATOM   4932 C  CA    . TYR C 1 223 ? 95.035  109.824 120.003 1.00 76.41  ? 223 TYR B CA    1 
ATOM   4933 C  C     . TYR C 1 223 ? 93.682  110.416 119.636 1.00 82.33  ? 223 TYR B C     1 
ATOM   4934 O  O     . TYR C 1 223 ? 92.664  109.731 119.778 1.00 87.83  ? 223 TYR B O     1 
ATOM   4935 C  CB    . TYR C 1 223 ? 95.239  109.911 121.518 1.00 73.88  ? 223 TYR B CB    1 
ATOM   4936 C  CG    . TYR C 1 223 ? 95.056  111.300 122.081 1.00 76.91  ? 223 TYR B CG    1 
ATOM   4937 C  CD1   . TYR C 1 223 ? 96.100  112.211 122.081 1.00 73.98  ? 223 TYR B CD1   1 
ATOM   4938 C  CD2   . TYR C 1 223 ? 93.840  111.701 122.615 1.00 83.57  ? 223 TYR B CD2   1 
ATOM   4939 C  CE1   . TYR C 1 223 ? 95.938  113.482 122.593 1.00 80.26  ? 223 TYR B CE1   1 
ATOM   4940 C  CE2   . TYR C 1 223 ? 93.669  112.970 123.127 1.00 83.77  ? 223 TYR B CE2   1 
ATOM   4941 C  CZ    . TYR C 1 223 ? 94.720  113.856 123.113 1.00 83.69  ? 223 TYR B CZ    1 
ATOM   4942 O  OH    . TYR C 1 223 ? 94.554  115.121 123.625 1.00 85.76  ? 223 TYR B OH    1 
ATOM   4943 N  N     . GLN C 1 224 ? 93.648  111.671 119.179 1.00 84.59  ? 224 GLN B N     1 
ATOM   4944 C  CA    . GLN C 1 224 ? 92.376  112.310 118.856 1.00 85.60  ? 224 GLN B CA    1 
ATOM   4945 C  C     . GLN C 1 224 ? 91.670  111.595 117.712 1.00 90.85  ? 224 GLN B C     1 
ATOM   4946 O  O     . GLN C 1 224 ? 90.443  111.450 117.723 1.00 94.82  ? 224 GLN B O     1 
ATOM   4947 C  CB    . GLN C 1 224 ? 92.603  113.779 118.505 1.00 85.54  ? 224 GLN B CB    1 
ATOM   4948 C  CG    . GLN C 1 224 ? 92.783  114.685 119.708 1.00 88.73  ? 224 GLN B CG    1 
ATOM   4949 C  CD    . GLN C 1 224 ? 93.611  115.912 119.390 1.00 97.89  ? 224 GLN B CD    1 
ATOM   4950 O  OE1   . GLN C 1 224 ? 94.239  115.995 118.334 1.00 96.17  ? 224 GLN B OE1   1 
ATOM   4951 N  NE2   . GLN C 1 224 ? 93.618  116.874 120.304 1.00 101.42 ? 224 GLN B NE2   1 
ATOM   4952 N  N     . ARG C 1 225 ? 92.430  111.147 116.712 1.00 89.97  ? 225 ARG B N     1 
ATOM   4953 C  CA    . ARG C 1 225 ? 91.826  110.506 115.550 1.00 89.86  ? 225 ARG B CA    1 
ATOM   4954 C  C     . ARG C 1 225 ? 91.148  109.192 115.913 1.00 92.90  ? 225 ARG B C     1 
ATOM   4955 O  O     . ARG C 1 225 ? 90.170  108.802 115.265 1.00 100.08 ? 225 ARG B O     1 
ATOM   4956 C  CB    . ARG C 1 225 ? 92.887  110.286 114.474 1.00 84.01  ? 225 ARG B CB    1 
ATOM   4957 C  CG    . ARG C 1 225 ? 93.593  111.563 114.058 1.00 83.89  ? 225 ARG B CG    1 
ATOM   4958 C  CD    . ARG C 1 225 ? 94.471  111.355 112.834 1.00 87.55  ? 225 ARG B CD    1 
ATOM   4959 N  NE    . ARG C 1 225 ? 95.150  112.575 112.407 1.00 88.10  ? 225 ARG B NE    1 
ATOM   4960 C  CZ    . ARG C 1 225 ? 95.987  113.288 113.152 1.00 89.60  ? 225 ARG B CZ    1 
ATOM   4961 N  NH1   . ARG C 1 225 ? 96.328  112.909 114.374 1.00 87.29  ? 225 ARG B NH1   1 
ATOM   4962 N  NH2   . ARG C 1 225 ? 96.512  114.402 112.650 1.00 95.53  ? 225 ARG B NH2   1 
ATOM   4963 N  N     . LEU C 1 226 ? 91.641  108.501 116.939 1.00 88.88  ? 226 LEU B N     1 
ATOM   4964 C  CA    . LEU C 1 226 ? 91.088  107.223 117.364 1.00 85.58  ? 226 LEU B CA    1 
ATOM   4965 C  C     . LEU C 1 226 ? 90.134  107.352 118.543 1.00 87.40  ? 226 LEU B C     1 
ATOM   4966 O  O     . LEU C 1 226 ? 89.733  106.332 119.113 1.00 91.95  ? 226 LEU B O     1 
ATOM   4967 C  CB    . LEU C 1 226 ? 92.215  106.252 117.713 1.00 79.71  ? 226 LEU B CB    1 
ATOM   4968 C  CG    . LEU C 1 226 ? 92.691  105.362 116.568 1.00 83.56  ? 226 LEU B CG    1 
ATOM   4969 C  CD1   . LEU C 1 226 ? 93.784  106.052 115.790 1.00 84.69  ? 226 LEU B CD1   1 
ATOM   4970 C  CD2   . LEU C 1 226 ? 93.184  104.036 117.101 1.00 83.68  ? 226 LEU B CD2   1 
ATOM   4971 N  N     . GLN C 1 227 ? 89.772  108.573 118.928 1.00 86.42  ? 227 GLN B N     1 
ATOM   4972 C  CA    . GLN C 1 227 ? 88.878  108.784 120.062 1.00 88.26  ? 227 GLN B CA    1 
ATOM   4973 C  C     . GLN C 1 227 ? 87.508  108.201 119.747 1.00 93.17  ? 227 GLN B C     1 
ATOM   4974 O  O     . GLN C 1 227 ? 86.825  108.659 118.826 1.00 100.92 ? 227 GLN B O     1 
ATOM   4975 C  CB    . GLN C 1 227 ? 88.777  110.272 120.381 1.00 91.22  ? 227 GLN B CB    1 
ATOM   4976 C  CG    . GLN C 1 227 ? 89.727  110.741 121.467 1.00 93.53  ? 227 GLN B CG    1 
ATOM   4977 C  CD    . GLN C 1 227 ? 89.243  112.001 122.153 1.00 96.74  ? 227 GLN B CD    1 
ATOM   4978 O  OE1   . GLN C 1 227 ? 88.069  112.120 122.502 1.00 103.55 ? 227 GLN B OE1   1 
ATOM   4979 N  NE2   . GLN C 1 227 ? 90.148  112.951 122.351 1.00 92.53  ? 227 GLN B NE2   1 
ATOM   4980 N  N     . GLY C 1 228 ? 87.101  107.190 120.510 1.00 93.85  ? 228 GLY B N     1 
ATOM   4981 C  CA    . GLY C 1 228 ? 85.821  106.554 120.279 1.00 96.72  ? 228 GLY B CA    1 
ATOM   4982 C  C     . GLY C 1 228 ? 85.795  105.586 119.120 1.00 96.92  ? 228 GLY B C     1 
ATOM   4983 O  O     . GLY C 1 228 ? 84.743  105.399 118.503 1.00 99.97  ? 228 GLY B O     1 
ATOM   4984 N  N     . ARG C 1 229 ? 86.931  104.962 118.801 1.00 93.39  ? 229 ARG B N     1 
ATOM   4985 C  CA    . ARG C 1 229 ? 87.014  104.027 117.687 1.00 94.70  ? 229 ARG B CA    1 
ATOM   4986 C  C     . ARG C 1 229 ? 87.785  102.761 118.039 1.00 99.33  ? 229 ARG B C     1 
ATOM   4987 O  O     . ARG C 1 229 ? 88.082  101.964 117.141 1.00 106.17 ? 229 ARG B O     1 
ATOM   4988 C  CB    . ARG C 1 229 ? 87.659  104.699 116.471 1.00 96.85  ? 229 ARG B CB    1 
ATOM   4989 C  CG    . ARG C 1 229 ? 86.671  105.329 115.508 1.00 98.07  ? 229 ARG B CG    1 
ATOM   4990 C  CD    . ARG C 1 229 ? 87.384  105.941 114.314 1.00 102.23 ? 229 ARG B CD    1 
ATOM   4991 N  NE    . ARG C 1 229 ? 87.721  107.344 114.529 1.00 104.92 ? 229 ARG B NE    1 
ATOM   4992 C  CZ    . ARG C 1 229 ? 86.842  108.337 114.544 1.00 104.88 ? 229 ARG B CZ    1 
ATOM   4993 N  NH1   . ARG C 1 229 ? 85.551  108.122 114.354 1.00 103.40 ? 229 ARG B NH1   1 
ATOM   4994 N  NH2   . ARG C 1 229 ? 87.271  109.579 114.751 1.00 101.81 ? 229 ARG B NH2   1 
ATOM   4995 N  N     . VAL C 1 230 ? 88.117  102.553 119.309 1.00 97.97  ? 230 VAL B N     1 
ATOM   4996 C  CA    . VAL C 1 230 ? 88.924  101.419 119.746 1.00 98.30  ? 230 VAL B CA    1 
ATOM   4997 C  C     . VAL C 1 230 ? 88.026  100.467 120.522 1.00 102.42 ? 230 VAL B C     1 
ATOM   4998 O  O     . VAL C 1 230 ? 87.370  100.872 121.490 1.00 108.39 ? 230 VAL B O     1 
ATOM   4999 C  CB    . VAL C 1 230 ? 90.115  101.870 120.603 1.00 94.21  ? 230 VAL B CB    1 
ATOM   5000 C  CG1   . VAL C 1 230 ? 90.748  100.679 121.295 1.00 87.66  ? 230 VAL B CG1   1 
ATOM   5001 C  CG2   . VAL C 1 230 ? 91.135  102.597 119.749 1.00 94.13  ? 230 VAL B CG2   1 
ATOM   5002 N  N     . GLN C 1 231 ? 87.993  99.206  120.100 1.00 100.12 ? 231 GLN B N     1 
ATOM   5003 C  CA    . GLN C 1 231 ? 87.219  98.205  120.808 1.00 100.44 ? 231 GLN B CA    1 
ATOM   5004 C  C     . GLN C 1 231 ? 87.917  97.826  122.112 1.00 101.93 ? 231 GLN B C     1 
ATOM   5005 O  O     . GLN C 1 231 ? 89.131  97.996  122.248 1.00 104.20 ? 231 GLN B O     1 
ATOM   5006 C  CB    . GLN C 1 231 ? 87.022  96.970  119.934 1.00 104.04 ? 231 GLN B CB    1 
ATOM   5007 C  CG    . GLN C 1 231 ? 86.227  97.234  118.668 1.00 108.72 ? 231 GLN B CG    1 
ATOM   5008 C  CD    . GLN C 1 231 ? 84.785  96.786  118.784 1.00 110.34 ? 231 GLN B CD    1 
ATOM   5009 O  OE1   . GLN C 1 231 ? 84.456  95.916  119.589 1.00 110.23 ? 231 GLN B OE1   1 
ATOM   5010 N  NE2   . GLN C 1 231 ? 83.914  97.382  117.978 1.00 108.97 ? 231 GLN B NE2   1 
ATOM   5011 N  N     . PRO C 1 232 ? 87.164  97.327  123.096 1.00 100.89 ? 232 PRO B N     1 
ATOM   5012 C  CA    . PRO C 1 232 ? 87.796  96.930  124.367 1.00 98.88  ? 232 PRO B CA    1 
ATOM   5013 C  C     . PRO C 1 232 ? 88.894  95.896  124.200 1.00 95.82  ? 232 PRO B C     1 
ATOM   5014 O  O     . PRO C 1 232 ? 89.890  95.942  124.933 1.00 92.90  ? 232 PRO B O     1 
ATOM   5015 C  CB    . PRO C 1 232 ? 86.630  96.370  125.196 1.00 101.44 ? 232 PRO B CB    1 
ATOM   5016 C  CG    . PRO C 1 232 ? 85.396  96.520  124.371 1.00 106.98 ? 232 PRO B CG    1 
ATOM   5017 C  CD    . PRO C 1 232 ? 85.695  97.355  123.178 1.00 104.98 ? 232 PRO B CD    1 
ATOM   5018 N  N     . GLY C 1 233 ? 88.745  94.962  123.263 1.00 97.23  ? 233 GLY B N     1 
ATOM   5019 C  CA    . GLY C 1 233 ? 89.771  93.962  123.040 1.00 93.54  ? 233 GLY B CA    1 
ATOM   5020 C  C     . GLY C 1 233 ? 90.900  94.387  122.130 1.00 93.22  ? 233 GLY B C     1 
ATOM   5021 O  O     . GLY C 1 233 ? 91.891  93.659  122.017 1.00 92.92  ? 233 GLY B O     1 
ATOM   5022 N  N     . GLU C 1 234 ? 90.780  95.542  121.481 1.00 94.28  ? 234 GLU B N     1 
ATOM   5023 C  CA    . GLU C 1 234 ? 91.803  96.025  120.565 1.00 91.76  ? 234 GLU B CA    1 
ATOM   5024 C  C     . GLU C 1 234 ? 92.912  96.801  121.261 1.00 91.32  ? 234 GLU B C     1 
ATOM   5025 O  O     . GLU C 1 234 ? 93.857  97.228  120.592 1.00 92.36  ? 234 GLU B O     1 
ATOM   5026 C  CB    . GLU C 1 234 ? 91.171  96.898  119.476 1.00 94.93  ? 234 GLU B CB    1 
ATOM   5027 C  CG    . GLU C 1 234 ? 90.494  96.109  118.368 1.00 99.38  ? 234 GLU B CG    1 
ATOM   5028 C  CD    . GLU C 1 234 ? 89.788  96.998  117.363 1.00 109.63 ? 234 GLU B CD    1 
ATOM   5029 O  OE1   . GLU C 1 234 ? 89.534  96.533  116.232 1.00 108.44 ? 234 GLU B OE1   1 
ATOM   5030 O  OE2   . GLU C 1 234 ? 89.489  98.162  117.704 1.00 109.88 ? 234 GLU B OE2   1 
ATOM   5031 N  N     . ILE C 1 235 ? 92.827  96.994  122.575 1.00 88.32  ? 235 ILE B N     1 
ATOM   5032 C  CA    . ILE C 1 235 ? 93.900  97.652  123.310 1.00 82.59  ? 235 ILE B CA    1 
ATOM   5033 C  C     . ILE C 1 235 ? 94.983  96.614  123.563 1.00 81.95  ? 235 ILE B C     1 
ATOM   5034 O  O     . ILE C 1 235 ? 94.959  95.901  124.572 1.00 81.05  ? 235 ILE B O     1 
ATOM   5035 C  CB    . ILE C 1 235 ? 93.393  98.274  124.623 1.00 80.54  ? 235 ILE B CB    1 
ATOM   5036 C  CG1   . ILE C 1 235 ? 92.246  99.244  124.339 1.00 79.57  ? 235 ILE B CG1   1 
ATOM   5037 C  CG2   . ILE C 1 235 ? 94.521  98.991  125.343 1.00 79.69  ? 235 ILE B CG2   1 
ATOM   5038 C  CD1   . ILE C 1 235 ? 91.667  99.887  125.575 1.00 81.35  ? 235 ILE B CD1   1 
ATOM   5039 N  N     . SER C 1 236 ? 95.940  96.525  122.638 1.00 85.40  ? 236 SER B N     1 
ATOM   5040 C  CA    . SER C 1 236 ? 96.890  95.419  122.657 1.00 87.33  ? 236 SER B CA    1 
ATOM   5041 C  C     . SER C 1 236 ? 97.880  95.541  123.807 1.00 87.70  ? 236 SER B C     1 
ATOM   5042 O  O     . SER C 1 236 ? 98.243  94.535  124.427 1.00 88.39  ? 236 SER B O     1 
ATOM   5043 C  CB    . SER C 1 236 ? 97.630  95.345  121.322 1.00 88.94  ? 236 SER B CB    1 
ATOM   5044 O  OG    . SER C 1 236 ? 98.168  94.053  121.109 1.00 93.98  ? 236 SER B OG    1 
ATOM   5045 N  N     . LEU C 1 237 ? 98.328  96.756  124.109 1.00 85.69  ? 237 LEU B N     1 
ATOM   5046 C  CA    . LEU C 1 237 ? 99.396  96.934  125.080 1.00 75.24  ? 237 LEU B CA    1 
ATOM   5047 C  C     . LEU C 1 237 ? 99.287  98.309  125.719 1.00 71.80  ? 237 LEU B C     1 
ATOM   5048 O  O     . LEU C 1 237 ? 98.841  99.270  125.090 1.00 78.47  ? 237 LEU B O     1 
ATOM   5049 C  CB    . LEU C 1 237 ? 100.766 96.758  124.415 1.00 71.74  ? 237 LEU B CB    1 
ATOM   5050 C  CG    . LEU C 1 237 ? 102.038 96.903  125.249 1.00 72.26  ? 237 LEU B CG    1 
ATOM   5051 C  CD1   . LEU C 1 237 ? 102.467 95.562  125.810 1.00 75.79  ? 237 LEU B CD1   1 
ATOM   5052 C  CD2   . LEU C 1 237 ? 103.140 97.496  124.395 1.00 74.03  ? 237 LEU B CD2   1 
ATOM   5053 N  N     . ALA C 1 238 ? 99.701  98.392  126.978 1.00 64.66  ? 238 ALA B N     1 
ATOM   5054 C  CA    . ALA C 1 238 ? 99.842  99.658  127.678 1.00 61.38  ? 238 ALA B CA    1 
ATOM   5055 C  C     . ALA C 1 238 ? 101.255 99.744  128.225 1.00 61.97  ? 238 ALA B C     1 
ATOM   5056 O  O     . ALA C 1 238 ? 101.785 98.760  128.748 1.00 67.15  ? 238 ALA B O     1 
ATOM   5057 C  CB    . ALA C 1 238 ? 98.825  99.794  128.811 1.00 64.24  ? 238 ALA B CB    1 
ATOM   5058 N  N     . VAL C 1 239 ? 101.872 100.913 128.093 1.00 55.66  ? 239 VAL B N     1 
ATOM   5059 C  CA    . VAL C 1 239 ? 103.261 101.102 128.482 1.00 46.53  ? 239 VAL B CA    1 
ATOM   5060 C  C     . VAL C 1 239 ? 103.349 102.297 129.417 1.00 48.87  ? 239 VAL B C     1 
ATOM   5061 O  O     . VAL C 1 239 ? 102.825 103.373 129.109 1.00 59.06  ? 239 VAL B O     1 
ATOM   5062 C  CB    . VAL C 1 239 ? 104.174 101.308 127.261 1.00 44.48  ? 239 VAL B CB    1 
ATOM   5063 C  CG1   . VAL C 1 239 ? 105.462 101.964 127.684 1.00 42.69  ? 239 VAL B CG1   1 
ATOM   5064 C  CG2   . VAL C 1 239 ? 104.456 99.987  126.585 1.00 53.71  ? 239 VAL B CG2   1 
ATOM   5065 N  N     . ALA C 1 240 ? 104.008 102.102 130.555 1.00 46.41  ? 240 ALA B N     1 
ATOM   5066 C  CA    . ALA C 1 240 ? 104.327 103.176 131.488 1.00 47.65  ? 240 ALA B CA    1 
ATOM   5067 C  C     . ALA C 1 240 ? 105.830 103.408 131.431 1.00 49.33  ? 240 ALA B C     1 
ATOM   5068 O  O     . ALA C 1 240 ? 106.614 102.530 131.807 1.00 57.03  ? 240 ALA B O     1 
ATOM   5069 C  CB    . ALA C 1 240 ? 103.873 102.830 132.904 1.00 46.87  ? 240 ALA B CB    1 
ATOM   5070 N  N     . PHE C 1 241 ? 106.231 104.579 130.949 1.00 43.84  ? 241 PHE B N     1 
ATOM   5071 C  CA    . PHE C 1 241 ? 107.638 104.955 130.895 1.00 43.03  ? 241 PHE B CA    1 
ATOM   5072 C  C     . PHE C 1 241 ? 108.000 105.631 132.210 1.00 46.43  ? 241 PHE B C     1 
ATOM   5073 O  O     . PHE C 1 241 ? 107.585 106.765 132.468 1.00 54.66  ? 241 PHE B O     1 
ATOM   5074 C  CB    . PHE C 1 241 ? 107.909 105.878 129.712 1.00 49.95  ? 241 PHE B CB    1 
ATOM   5075 C  CG    . PHE C 1 241 ? 107.765 105.211 128.380 1.00 47.85  ? 241 PHE B CG    1 
ATOM   5076 C  CD1   . PHE C 1 241 ? 108.598 104.173 128.020 1.00 50.49  ? 241 PHE B CD1   1 
ATOM   5077 C  CD2   . PHE C 1 241 ? 106.798 105.627 127.486 1.00 51.30  ? 241 PHE B CD2   1 
ATOM   5078 C  CE1   . PHE C 1 241 ? 108.470 103.560 126.796 1.00 49.53  ? 241 PHE B CE1   1 
ATOM   5079 C  CE2   . PHE C 1 241 ? 106.667 105.017 126.261 1.00 55.40  ? 241 PHE B CE2   1 
ATOM   5080 C  CZ    . PHE C 1 241 ? 107.506 103.983 125.913 1.00 54.21  ? 241 PHE B CZ    1 
ATOM   5081 N  N     . ALA C 1 242 ? 108.774 104.937 133.038 1.00 42.15  ? 242 ALA B N     1 
ATOM   5082 C  CA    . ALA C 1 242 ? 109.181 105.438 134.349 1.00 46.73  ? 242 ALA B CA    1 
ATOM   5083 C  C     . ALA C 1 242 ? 110.686 105.245 134.470 1.00 43.28  ? 242 ALA B C     1 
ATOM   5084 O  O     . ALA C 1 242 ? 111.153 104.162 134.831 1.00 44.65  ? 242 ALA B O     1 
ATOM   5085 C  CB    . ALA C 1 242 ? 108.435 104.724 135.468 1.00 55.67  ? 242 ALA B CB    1 
ATOM   5086 N  N     . ARG C 1 243 ? 111.440 106.296 134.169 1.00 37.83  ? 243 ARG B N     1 
ATOM   5087 C  CA    . ARG C 1 243 ? 112.892 106.229 134.188 1.00 37.04  ? 243 ARG B CA    1 
ATOM   5088 C  C     . ARG C 1 243 ? 113.405 106.208 135.622 1.00 42.94  ? 243 ARG B C     1 
ATOM   5089 O  O     . ARG C 1 243 ? 113.038 107.062 136.432 1.00 48.69  ? 243 ARG B O     1 
ATOM   5090 C  CB    . ARG C 1 243 ? 113.473 107.421 133.433 1.00 33.31  ? 243 ARG B CB    1 
ATOM   5091 C  CG    . ARG C 1 243 ? 114.978 107.504 133.447 1.00 40.14  ? 243 ARG B CG    1 
ATOM   5092 C  CD    . ARG C 1 243 ? 115.436 108.874 132.989 1.00 41.26  ? 243 ARG B CD    1 
ATOM   5093 N  NE    . ARG C 1 243 ? 116.838 108.881 132.592 1.00 52.04  ? 243 ARG B NE    1 
ATOM   5094 C  CZ    . ARG C 1 243 ? 117.857 108.806 133.436 1.00 56.85  ? 243 ARG B CZ    1 
ATOM   5095 N  NH1   . ARG C 1 243 ? 117.670 108.727 134.743 1.00 45.08  ? 243 ARG B NH1   1 
ATOM   5096 N  NH2   . ARG C 1 243 ? 119.098 108.811 132.956 1.00 60.55  ? 243 ARG B NH2   1 
ATOM   5097 N  N     . SER C 1 244 ? 114.254 105.226 135.930 1.00 44.90  ? 244 SER B N     1 
ATOM   5098 C  CA    . SER C 1 244 ? 114.951 105.141 137.214 1.00 44.91  ? 244 SER B CA    1 
ATOM   5099 C  C     . SER C 1 244 ? 113.963 105.090 138.384 1.00 41.25  ? 244 SER B C     1 
ATOM   5100 O  O     . SER C 1 244 ? 113.856 106.012 139.192 1.00 47.63  ? 244 SER B O     1 
ATOM   5101 C  CB    . SER C 1 244 ? 115.937 106.301 137.378 1.00 50.45  ? 244 SER B CB    1 
ATOM   5102 O  OG    . SER C 1 244 ? 115.330 107.382 138.063 1.00 49.68  ? 244 SER B OG    1 
ATOM   5103 N  N     . LEU C 1 245 ? 113.221 103.987 138.429 1.00 41.48  ? 245 LEU B N     1 
ATOM   5104 C  CA    . LEU C 1 245 ? 112.275 103.766 139.514 1.00 45.31  ? 245 LEU B CA    1 
ATOM   5105 C  C     . LEU C 1 245 ? 112.976 103.751 140.868 1.00 46.36  ? 245 LEU B C     1 
ATOM   5106 O  O     . LEU C 1 245 ? 114.166 103.447 140.978 1.00 52.55  ? 245 LEU B O     1 
ATOM   5107 C  CB    . LEU C 1 245 ? 111.538 102.443 139.320 1.00 43.01  ? 245 LEU B CB    1 
ATOM   5108 C  CG    . LEU C 1 245 ? 110.671 102.294 138.076 1.00 46.12  ? 245 LEU B CG    1 
ATOM   5109 C  CD1   . LEU C 1 245 ? 110.616 100.844 137.665 1.00 50.88  ? 245 LEU B CD1   1 
ATOM   5110 C  CD2   . LEU C 1 245 ? 109.283 102.815 138.368 1.00 49.98  ? 245 LEU B CD2   1 
ATOM   5111 N  N     . ARG C 1 246 ? 112.217 104.086 141.905 1.00 41.54  ? 246 ARG B N     1 
ATOM   5112 C  CA    . ARG C 1 246 ? 112.635 103.962 143.291 1.00 39.03  ? 246 ARG B CA    1 
ATOM   5113 C  C     . ARG C 1 246 ? 111.737 102.951 143.992 1.00 46.35  ? 246 ARG B C     1 
ATOM   5114 O  O     . ARG C 1 246 ? 110.884 102.313 143.374 1.00 48.84  ? 246 ARG B O     1 
ATOM   5115 C  CB    . ARG C 1 246 ? 112.595 105.317 143.997 1.00 39.77  ? 246 ARG B CB    1 
ATOM   5116 C  CG    . ARG C 1 246 ? 113.628 106.298 143.499 1.00 40.50  ? 246 ARG B CG    1 
ATOM   5117 C  CD    . ARG C 1 246 ? 114.979 106.029 144.118 1.00 34.25  ? 246 ARG B CD    1 
ATOM   5118 N  NE    . ARG C 1 246 ? 115.940 107.070 143.780 1.00 38.78  ? 246 ARG B NE    1 
ATOM   5119 C  CZ    . ARG C 1 246 ? 116.725 107.042 142.712 1.00 44.41  ? 246 ARG B CZ    1 
ATOM   5120 N  NH1   . ARG C 1 246 ? 116.682 106.040 141.849 1.00 40.32  ? 246 ARG B NH1   1 
ATOM   5121 N  NH2   . ARG C 1 246 ? 117.573 108.044 142.505 1.00 45.17  ? 246 ARG B NH2   1 
ATOM   5122 N  N     . SER C 1 247 ? 111.927 102.814 145.300 1.00 47.36  ? 247 SER B N     1 
ATOM   5123 C  CA    . SER C 1 247 ? 111.181 101.821 146.060 1.00 46.40  ? 247 SER B CA    1 
ATOM   5124 C  C     . SER C 1 247 ? 109.806 102.310 146.496 1.00 50.20  ? 247 SER B C     1 
ATOM   5125 O  O     . SER C 1 247 ? 109.066 101.544 147.122 1.00 53.97  ? 247 SER B O     1 
ATOM   5126 C  CB    . SER C 1 247 ? 111.987 101.383 147.282 1.00 54.22  ? 247 SER B CB    1 
ATOM   5127 O  OG    . SER C 1 247 ? 112.726 100.206 147.004 1.00 59.81  ? 247 SER B OG    1 
ATOM   5128 N  N     . ASP C 1 248 ? 109.447 103.557 146.189 1.00 49.63  ? 248 ASP B N     1 
ATOM   5129 C  CA    . ASP C 1 248 ? 108.110 104.066 146.451 1.00 49.63  ? 248 ASP B CA    1 
ATOM   5130 C  C     . ASP C 1 248 ? 107.422 104.639 145.223 1.00 50.32  ? 248 ASP B C     1 
ATOM   5131 O  O     . ASP C 1 248 ? 106.196 104.779 145.238 1.00 54.04  ? 248 ASP B O     1 
ATOM   5132 C  CB    . ASP C 1 248 ? 108.144 105.144 147.546 1.00 55.68  ? 248 ASP B CB    1 
ATOM   5133 C  CG    . ASP C 1 248 ? 108.503 106.514 147.008 1.00 60.29  ? 248 ASP B CG    1 
ATOM   5134 O  OD1   . ASP C 1 248 ? 109.442 106.608 146.193 1.00 62.07  ? 248 ASP B OD1   1 
ATOM   5135 O  OD2   . ASP C 1 248 ? 107.844 107.499 147.403 1.00 61.26  ? 248 ASP B OD2   1 
ATOM   5136 N  N     . ARG C 1 249 ? 108.165 104.972 144.173 1.00 50.91  ? 249 ARG B N     1 
ATOM   5137 C  CA    . ARG C 1 249 ? 107.585 105.475 142.937 1.00 45.27  ? 249 ARG B CA    1 
ATOM   5138 C  C     . ARG C 1 249 ? 107.171 104.366 141.982 1.00 47.99  ? 249 ARG B C     1 
ATOM   5139 O  O     . ARG C 1 249 ? 106.646 104.663 140.905 1.00 51.95  ? 249 ARG B O     1 
ATOM   5140 C  CB    . ARG C 1 249 ? 108.568 106.413 142.234 1.00 41.89  ? 249 ARG B CB    1 
ATOM   5141 C  CG    . ARG C 1 249 ? 109.093 107.527 143.114 1.00 40.90  ? 249 ARG B CG    1 
ATOM   5142 C  CD    . ARG C 1 249 ? 109.702 108.639 142.290 1.00 37.77  ? 249 ARG B CD    1 
ATOM   5143 N  NE    . ARG C 1 249 ? 110.924 108.226 141.612 1.00 35.08  ? 249 ARG B NE    1 
ATOM   5144 C  CZ    . ARG C 1 249 ? 110.990 107.876 140.336 1.00 41.98  ? 249 ARG B CZ    1 
ATOM   5145 N  NH1   . ARG C 1 249 ? 109.913 107.860 139.567 1.00 44.07  ? 249 ARG B NH1   1 
ATOM   5146 N  NH2   . ARG C 1 249 ? 112.165 107.534 139.817 1.00 46.00  ? 249 ARG B NH2   1 
ATOM   5147 N  N     . LEU C 1 250 ? 107.401 103.104 142.335 1.00 50.68  ? 250 LEU B N     1 
ATOM   5148 C  CA    . LEU C 1 250 ? 106.914 102.007 141.513 1.00 49.45  ? 250 LEU B CA    1 
ATOM   5149 C  C     . LEU C 1 250 ? 105.483 101.620 141.847 1.00 50.55  ? 250 LEU B C     1 
ATOM   5150 O  O     . LEU C 1 250 ? 104.937 100.719 141.202 1.00 53.40  ? 250 LEU B O     1 
ATOM   5151 C  CB    . LEU C 1 250 ? 107.825 100.781 141.649 1.00 45.02  ? 250 LEU B CB    1 
ATOM   5152 C  CG    . LEU C 1 250 ? 107.999 100.114 143.012 1.00 49.97  ? 250 LEU B CG    1 
ATOM   5153 C  CD1   . LEU C 1 250 ? 106.998 98.991  143.201 1.00 57.83  ? 250 LEU B CD1   1 
ATOM   5154 C  CD2   . LEU C 1 250 ? 109.406 99.570  143.147 1.00 53.50  ? 250 LEU B CD2   1 
ATOM   5155 N  N     . TYR C 1 251 ? 104.866 102.269 142.833 1.00 48.55  ? 251 TYR B N     1 
ATOM   5156 C  CA    . TYR C 1 251 ? 103.485 101.986 143.188 1.00 50.22  ? 251 TYR B CA    1 
ATOM   5157 C  C     . TYR C 1 251 ? 102.490 102.863 142.446 1.00 55.70  ? 251 TYR B C     1 
ATOM   5158 O  O     . TYR C 1 251 ? 101.282 102.638 142.567 1.00 64.61  ? 251 TYR B O     1 
ATOM   5159 C  CB    . TYR C 1 251 ? 103.283 102.146 144.696 1.00 48.27  ? 251 TYR B CB    1 
ATOM   5160 C  CG    . TYR C 1 251 ? 103.995 101.093 145.507 1.00 52.31  ? 251 TYR B CG    1 
ATOM   5161 C  CD1   . TYR C 1 251 ? 103.563 99.776  145.500 1.00 55.96  ? 251 TYR B CD1   1 
ATOM   5162 C  CD2   . TYR C 1 251 ? 105.106 101.412 146.269 1.00 55.55  ? 251 TYR B CD2   1 
ATOM   5163 C  CE1   . TYR C 1 251 ? 104.215 98.809  146.234 1.00 62.07  ? 251 TYR B CE1   1 
ATOM   5164 C  CE2   . TYR C 1 251 ? 105.765 100.452 147.006 1.00 60.21  ? 251 TYR B CE2   1 
ATOM   5165 C  CZ    . TYR C 1 251 ? 105.315 99.152  146.986 1.00 63.48  ? 251 TYR B CZ    1 
ATOM   5166 O  OH    . TYR C 1 251 ? 105.971 98.194  147.721 1.00 67.74  ? 251 TYR B OH    1 
ATOM   5167 N  N     . GLN C 1 252 ? 102.956 103.850 141.691 1.00 53.14  ? 252 GLN B N     1 
ATOM   5168 C  CA    . GLN C 1 252 ? 102.039 104.605 140.849 1.00 52.78  ? 252 GLN B CA    1 
ATOM   5169 C  C     . GLN C 1 252 ? 101.722 103.820 139.578 1.00 59.84  ? 252 GLN B C     1 
ATOM   5170 O  O     . GLN C 1 252 ? 100.543 103.710 139.220 1.00 64.25  ? 252 GLN B O     1 
ATOM   5171 C  CB    . GLN C 1 252 ? 102.597 105.989 140.510 1.00 56.59  ? 252 GLN B CB    1 
ATOM   5172 C  CG    . GLN C 1 252 ? 101.706 106.772 139.564 1.00 63.03  ? 252 GLN B CG    1 
ATOM   5173 C  CD    . GLN C 1 252 ? 102.456 107.832 138.790 1.00 68.60  ? 252 GLN B CD    1 
ATOM   5174 O  OE1   . GLN C 1 252 ? 103.656 108.026 138.982 1.00 69.15  ? 252 GLN B OE1   1 
ATOM   5175 N  NE2   . GLN C 1 252 ? 101.750 108.527 137.906 1.00 65.45  ? 252 GLN B NE2   1 
ATOM   5176 N  N     . PRO C 1 253 ? 102.714 103.269 138.860 1.00 57.22  ? 253 PRO B N     1 
ATOM   5177 C  CA    . PRO C 1 253 ? 102.361 102.417 137.712 1.00 54.10  ? 253 PRO B CA    1 
ATOM   5178 C  C     . PRO C 1 253 ? 101.500 101.227 138.089 1.00 57.37  ? 253 PRO B C     1 
ATOM   5179 O  O     . PRO C 1 253 ? 100.563 100.891 137.354 1.00 60.30  ? 253 PRO B O     1 
ATOM   5180 C  CB    . PRO C 1 253 ? 103.730 101.984 137.171 1.00 48.30  ? 253 PRO B CB    1 
ATOM   5181 C  CG    . PRO C 1 253 ? 104.632 103.080 137.555 1.00 48.40  ? 253 PRO B CG    1 
ATOM   5182 C  CD    . PRO C 1 253 ? 104.172 103.486 138.920 1.00 51.97  ? 253 PRO B CD    1 
ATOM   5183 N  N     . LEU C 1 254 ? 101.776 100.595 139.234 1.00 57.34  ? 254 LEU B N     1 
ATOM   5184 C  CA    . LEU C 1 254 ? 100.974 99.456  139.669 1.00 55.55  ? 254 LEU B CA    1 
ATOM   5185 C  C     . LEU C 1 254 ? 99.507  99.842  139.789 1.00 58.05  ? 254 LEU B C     1 
ATOM   5186 O  O     . LEU C 1 254 ? 98.629  99.182  139.221 1.00 68.14  ? 254 LEU B O     1 
ATOM   5187 C  CB    . LEU C 1 254 ? 101.500 98.923  141.000 1.00 50.05  ? 254 LEU B CB    1 
ATOM   5188 C  CG    . LEU C 1 254 ? 102.460 97.739  140.913 1.00 55.02  ? 254 LEU B CG    1 
ATOM   5189 C  CD1   . LEU C 1 254 ? 103.082 97.458  142.265 1.00 62.80  ? 254 LEU B CD1   1 
ATOM   5190 C  CD2   . LEU C 1 254 ? 101.735 96.517  140.397 1.00 58.54  ? 254 LEU B CD2   1 
ATOM   5191 N  N     . TYR C 1 255 ? 99.227  100.933 140.503 1.00 50.31  ? 255 TYR B N     1 
ATOM   5192 C  CA    . TYR C 1 255 ? 97.865  101.449 140.548 1.00 54.63  ? 255 TYR B CA    1 
ATOM   5193 C  C     . TYR C 1 255 ? 97.360  101.756 139.146 1.00 62.85  ? 255 TYR B C     1 
ATOM   5194 O  O     . TYR C 1 255 ? 96.226  101.405 138.799 1.00 68.96  ? 255 TYR B O     1 
ATOM   5195 C  CB    . TYR C 1 255 ? 97.805  102.693 141.432 1.00 56.11  ? 255 TYR B CB    1 
ATOM   5196 C  CG    . TYR C 1 255 ? 96.415  103.046 141.903 1.00 59.85  ? 255 TYR B CG    1 
ATOM   5197 C  CD1   . TYR C 1 255 ? 95.770  102.278 142.860 1.00 60.08  ? 255 TYR B CD1   1 
ATOM   5198 C  CD2   . TYR C 1 255 ? 95.751  104.154 141.399 1.00 59.54  ? 255 TYR B CD2   1 
ATOM   5199 C  CE1   . TYR C 1 255 ? 94.503  102.599 143.294 1.00 64.16  ? 255 TYR B CE1   1 
ATOM   5200 C  CE2   . TYR C 1 255 ? 94.483  104.483 141.829 1.00 60.76  ? 255 TYR B CE2   1 
ATOM   5201 C  CZ    . TYR C 1 255 ? 93.864  103.702 142.777 1.00 66.18  ? 255 TYR B CZ    1 
ATOM   5202 O  OH    . TYR C 1 255 ? 92.599  104.025 143.209 1.00 71.71  ? 255 TYR B OH    1 
ATOM   5203 N  N     . GLU C 1 256 ? 98.211  102.361 138.310 1.00 64.56  ? 256 GLU B N     1 
ATOM   5204 C  CA    . GLU C 1 256 ? 97.831  102.650 136.931 1.00 64.84  ? 256 GLU B CA    1 
ATOM   5205 C  C     . GLU C 1 256 ? 97.356  101.398 136.215 1.00 67.50  ? 256 GLU B C     1 
ATOM   5206 O  O     . GLU C 1 256 ? 96.494  101.475 135.333 1.00 70.15  ? 256 GLU B O     1 
ATOM   5207 C  CB    . GLU C 1 256 ? 99.010  103.265 136.172 1.00 64.72  ? 256 GLU B CB    1 
ATOM   5208 C  CG    . GLU C 1 256 ? 99.295  104.720 136.500 1.00 66.80  ? 256 GLU B CG    1 
ATOM   5209 C  CD    . GLU C 1 256 ? 100.441 105.285 135.681 1.00 73.26  ? 256 GLU B CD    1 
ATOM   5210 O  OE1   . GLU C 1 256 ? 100.826 104.653 134.677 1.00 73.88  ? 256 GLU B OE1   1 
ATOM   5211 O  OE2   . GLU C 1 256 ? 100.962 106.360 136.044 1.00 71.44  ? 256 GLU B OE2   1 
ATOM   5212 N  N     . ALA C 1 257 ? 97.900  100.238 136.581 1.00 60.82  ? 257 ALA B N     1 
ATOM   5213 C  CA    . ALA C 1 257 ? 97.437  98.980  136.017 1.00 59.25  ? 257 ALA B CA    1 
ATOM   5214 C  C     . ALA C 1 257 ? 96.286  98.385  136.814 1.00 66.10  ? 257 ALA B C     1 
ATOM   5215 O  O     . ALA C 1 257 ? 95.359  97.818  136.225 1.00 74.94  ? 257 ALA B O     1 
ATOM   5216 C  CB    . ALA C 1 257 ? 98.590  97.978  135.940 1.00 54.76  ? 257 ALA B CB    1 
ATOM   5217 N  N     . ASN C 1 258 ? 96.314  98.523  138.143 1.00 61.45  ? 258 ASN B N     1 
ATOM   5218 C  CA    . ASN C 1 258 ? 95.317  97.850  138.971 1.00 58.07  ? 258 ASN B CA    1 
ATOM   5219 C  C     . ASN C 1 258 ? 93.917  98.362  138.671 1.00 69.68  ? 258 ASN B C     1 
ATOM   5220 O  O     . ASN C 1 258 ? 92.960  97.581  138.617 1.00 80.44  ? 258 ASN B O     1 
ATOM   5221 C  CB    . ASN C 1 258 ? 95.651  98.030  140.451 1.00 59.52  ? 258 ASN B CB    1 
ATOM   5222 C  CG    . ASN C 1 258 ? 96.593  96.963  140.968 1.00 72.97  ? 258 ASN B CG    1 
ATOM   5223 O  OD1   . ASN C 1 258 ? 97.192  96.220  140.193 1.00 76.28  ? 258 ASN B OD1   1 
ATOM   5224 N  ND2   . ASN C 1 258 ? 96.725  96.880  142.284 1.00 79.10  ? 258 ASN B ND2   1 
ATOM   5225 N  N     . VAL C 1 259 ? 93.776  99.673  138.477 1.00 69.35  ? 259 VAL B N     1 
ATOM   5226 C  CA    . VAL C 1 259 ? 92.502  100.216 138.023 1.00 64.86  ? 259 VAL B CA    1 
ATOM   5227 C  C     . VAL C 1 259 ? 92.234  99.796  136.583 1.00 72.45  ? 259 VAL B C     1 
ATOM   5228 O  O     . VAL C 1 259 ? 91.107  99.423  136.231 1.00 80.90  ? 259 VAL B O     1 
ATOM   5229 C  CB    . VAL C 1 259 ? 92.491  101.746 138.186 1.00 64.25  ? 259 VAL B CB    1 
ATOM   5230 C  CG1   . VAL C 1 259 ? 91.550  102.389 137.183 1.00 70.19  ? 259 VAL B CG1   1 
ATOM   5231 C  CG2   . VAL C 1 259 ? 92.102  102.120 139.602 1.00 65.71  ? 259 VAL B CG2   1 
ATOM   5232 N  N     . MET C 1 260 ? 93.273  99.811  135.742 1.00 73.15  ? 260 MET B N     1 
ATOM   5233 C  CA    . MET C 1 260 ? 93.093  99.577  134.312 1.00 77.57  ? 260 MET B CA    1 
ATOM   5234 C  C     . MET C 1 260 ? 92.398  98.248  134.051 1.00 78.39  ? 260 MET B C     1 
ATOM   5235 O  O     . MET C 1 260 ? 91.342  98.202  133.408 1.00 84.65  ? 260 MET B O     1 
ATOM   5236 C  CB    . MET C 1 260 ? 94.449  99.616  133.609 1.00 72.07  ? 260 MET B CB    1 
ATOM   5237 C  CG    . MET C 1 260 ? 94.380  99.564  132.098 1.00 75.09  ? 260 MET B CG    1 
ATOM   5238 S  SD    . MET C 1 260 ? 95.792  100.366 131.320 1.00 85.05  ? 260 MET B SD    1 
ATOM   5239 C  CE    . MET C 1 260 ? 95.298  100.316 129.601 1.00 86.22  ? 260 MET B CE    1 
ATOM   5240 N  N     . GLN C 1 261 ? 92.951  97.159  134.587 1.00 73.86  ? 261 GLN B N     1 
ATOM   5241 C  CA    . GLN C 1 261 ? 92.333  95.853  134.398 1.00 80.51  ? 261 GLN B CA    1 
ATOM   5242 C  C     . GLN C 1 261 ? 90.928  95.829  134.978 1.00 82.82  ? 261 GLN B C     1 
ATOM   5243 O  O     . GLN C 1 261 ? 90.021  95.217  134.402 1.00 88.57  ? 261 GLN B O     1 
ATOM   5244 C  CB    . GLN C 1 261 ? 93.201  94.767  135.029 1.00 82.21  ? 261 GLN B CB    1 
ATOM   5245 C  CG    . GLN C 1 261 ? 94.628  94.756  134.516 1.00 78.60  ? 261 GLN B CG    1 
ATOM   5246 C  CD    . GLN C 1 261 ? 95.504  93.765  135.250 1.00 88.13  ? 261 GLN B CD    1 
ATOM   5247 O  OE1   . GLN C 1 261 ? 95.037  93.039  136.127 1.00 96.98  ? 261 GLN B OE1   1 
ATOM   5248 N  NE2   . GLN C 1 261 ? 96.782  93.728  134.894 1.00 84.23  ? 261 GLN B NE2   1 
ATOM   5249 N  N     . LEU C 1 262 ? 90.723  96.520  136.103 1.00 76.64  ? 262 LEU B N     1 
ATOM   5250 C  CA    . LEU C 1 262 ? 89.394  96.596  136.698 1.00 80.20  ? 262 LEU B CA    1 
ATOM   5251 C  C     . LEU C 1 262 ? 88.368  97.120  135.705 1.00 88.34  ? 262 LEU B C     1 
ATOM   5252 O  O     . LEU C 1 262 ? 87.212  96.681  135.718 1.00 97.90  ? 262 LEU B O     1 
ATOM   5253 C  CB    . LEU C 1 262 ? 89.429  97.483  137.943 1.00 78.73  ? 262 LEU B CB    1 
ATOM   5254 C  CG    . LEU C 1 262 ? 88.096  97.751  138.643 1.00 81.17  ? 262 LEU B CG    1 
ATOM   5255 C  CD1   . LEU C 1 262 ? 87.377  96.451  138.937 1.00 88.49  ? 262 LEU B CD1   1 
ATOM   5256 C  CD2   . LEU C 1 262 ? 88.312  98.542  139.918 1.00 81.69  ? 262 LEU B CD2   1 
ATOM   5257 N  N     . LEU C 1 263 ? 88.765  98.042  134.834 1.00 86.35  ? 263 LEU B N     1 
ATOM   5258 C  CA    . LEU C 1 263 ? 87.847  98.612  133.862 1.00 84.94  ? 263 LEU B CA    1 
ATOM   5259 C  C     . LEU C 1 263 ? 87.911  97.920  132.509 1.00 91.36  ? 263 LEU B C     1 
ATOM   5260 O  O     . LEU C 1 263 ? 87.190  98.322  131.591 1.00 94.89  ? 263 LEU B O     1 
ATOM   5261 C  CB    . LEU C 1 263 ? 88.120  100.109 133.696 1.00 85.38  ? 263 LEU B CB    1 
ATOM   5262 C  CG    . LEU C 1 263 ? 88.153  100.896 135.007 1.00 84.02  ? 263 LEU B CG    1 
ATOM   5263 C  CD1   . LEU C 1 263 ? 88.704  102.294 134.787 1.00 84.49  ? 263 LEU B CD1   1 
ATOM   5264 C  CD2   . LEU C 1 263 ? 86.777  100.947 135.645 1.00 80.73  ? 263 LEU B CD2   1 
ATOM   5265 N  N     . LEU C 1 264 ? 88.743  96.888  132.360 1.00 92.32  ? 264 LEU B N     1 
ATOM   5266 C  CA    . LEU C 1 264 ? 88.857  96.212  131.074 1.00 91.73  ? 264 LEU B CA    1 
ATOM   5267 C  C     . LEU C 1 264 ? 88.660  94.708  131.220 1.00 95.09  ? 264 LEU B C     1 
ATOM   5268 O  O     . LEU C 1 264 ? 88.176  94.050  130.294 1.00 101.90 ? 264 LEU B O     1 
ATOM   5269 C  CB    . LEU C 1 264 ? 90.211  96.514  130.427 1.00 90.22  ? 264 LEU B CB    1 
ATOM   5270 C  CG    . LEU C 1 264 ? 90.157  97.433  129.204 1.00 92.06  ? 264 LEU B CG    1 
ATOM   5271 C  CD1   . LEU C 1 264 ? 89.777  98.847  129.608 1.00 92.84  ? 264 LEU B CD1   1 
ATOM   5272 C  CD2   . LEU C 1 264 ? 91.474  97.427  128.449 1.00 88.37  ? 264 LEU B CD2   1 
ATOM   5273 N  N     . GLU C 1 265 ? 89.025  94.156  132.375 1.00 92.41  ? 265 GLU B N     1 
ATOM   5274 C  CA    . GLU C 1 265 ? 88.838  92.731  132.621 1.00 95.87  ? 265 GLU B CA    1 
ATOM   5275 C  C     . GLU C 1 265 ? 87.530  92.444  133.351 1.00 102.12 ? 265 GLU B C     1 
ATOM   5276 O  O     . GLU C 1 265 ? 86.727  91.625  132.893 1.00 105.58 ? 265 GLU B O     1 
ATOM   5277 C  CB    . GLU C 1 265 ? 90.015  92.173  133.426 1.00 91.75  ? 265 GLU B CB    1 
ATOM   5278 C  CG    . GLU C 1 265 ? 91.289  91.972  132.631 1.00 94.78  ? 265 GLU B CG    1 
ATOM   5279 C  CD    . GLU C 1 265 ? 91.944  90.639  132.932 1.00 102.60 ? 265 GLU B CD    1 
ATOM   5280 O  OE1   . GLU C 1 265 ? 91.387  89.874  133.746 1.00 102.86 ? 265 GLU B OE1   1 
ATOM   5281 O  OE2   . GLU C 1 265 ? 93.018  90.358  132.363 1.00 103.48 ? 265 GLU B OE2   1 
ATOM   5282 N  N     . GLY C 1 266 ? 87.304  93.107  134.484 1.00 97.50  ? 266 GLY B N     1 
ATOM   5283 C  CA    . GLY C 1 266 ? 86.145  92.818  135.304 1.00 97.42  ? 266 GLY B CA    1 
ATOM   5284 C  C     . GLY C 1 266 ? 84.861  93.504  134.896 1.00 101.00 ? 266 GLY B C     1 
ATOM   5285 O  O     . GLY C 1 266 ? 83.816  93.220  135.489 1.00 106.73 ? 266 GLY B O     1 
ATOM   5286 N  N     . LYS C 1 267 ? 84.901  94.398  133.905 1.00 98.09  ? 267 LYS B N     1 
ATOM   5287 C  CA    . LYS C 1 267 ? 83.710  95.128  133.496 1.00 101.74 ? 267 LYS B CA    1 
ATOM   5288 C  C     . LYS C 1 267 ? 83.520  95.218  131.989 1.00 104.12 ? 267 LYS B C     1 
ATOM   5289 O  O     . LYS C 1 267 ? 82.522  95.797  131.546 1.00 106.85 ? 267 LYS B O     1 
ATOM   5290 C  CB    . LYS C 1 267 ? 83.722  96.547  134.084 1.00 98.23  ? 267 LYS B CB    1 
ATOM   5291 C  CG    . LYS C 1 267 ? 83.708  96.584  135.598 1.00 98.07  ? 267 LYS B CG    1 
ATOM   5292 C  CD    . LYS C 1 267 ? 82.426  97.200  136.118 1.00 101.02 ? 267 LYS B CD    1 
ATOM   5293 C  CE    . LYS C 1 267 ? 82.155  96.770  137.548 1.00 104.77 ? 267 LYS B CE    1 
ATOM   5294 N  NZ    . LYS C 1 267 ? 83.385  96.837  138.380 1.00 109.27 ? 267 LYS B NZ    1 
ATOM   5295 N  N     . LEU C 1 268 ? 84.435  94.670  131.189 1.00 99.32  ? 268 LEU B N     1 
ATOM   5296 C  CA    . LEU C 1 268 ? 84.303  94.713  129.741 1.00 100.95 ? 268 LEU B CA    1 
ATOM   5297 C  C     . LEU C 1 268 ? 84.534  93.375  129.056 1.00 104.32 ? 268 LEU B C     1 
ATOM   5298 O  O     . LEU C 1 268 ? 84.209  93.251  127.870 1.00 109.59 ? 268 LEU B O     1 
ATOM   5299 C  CB    . LEU C 1 268 ? 85.267  95.748  129.141 1.00 102.68 ? 268 LEU B CB    1 
ATOM   5300 C  CG    . LEU C 1 268 ? 84.877  97.212  129.348 1.00 100.51 ? 268 LEU B CG    1 
ATOM   5301 C  CD1   . LEU C 1 268 ? 85.833  98.129  128.610 1.00 98.85  ? 268 LEU B CD1   1 
ATOM   5302 C  CD2   . LEU C 1 268 ? 83.447  97.452  128.897 1.00 101.66 ? 268 LEU B CD2   1 
ATOM   5303 N  N     . GLY C 1 269 ? 85.077  92.379  129.750 1.00 100.64 ? 269 GLY B N     1 
ATOM   5304 C  CA    . GLY C 1 269 ? 85.264  91.069  129.165 1.00 103.65 ? 269 GLY B CA    1 
ATOM   5305 C  C     . GLY C 1 269 ? 86.468  90.921  128.265 1.00 108.09 ? 269 GLY B C     1 
ATOM   5306 O  O     . GLY C 1 269 ? 86.559  89.921  127.543 1.00 114.72 ? 269 GLY B O     1 
ATOM   5307 N  N     . ALA C 1 270 ? 87.392  91.878  128.274 1.00 103.98 ? 270 ALA B N     1 
ATOM   5308 C  CA    . ALA C 1 270 ? 88.606  91.739  127.489 1.00 104.21 ? 270 ALA B CA    1 
ATOM   5309 C  C     . ALA C 1 270 ? 89.442  90.578  128.024 1.00 107.92 ? 270 ALA B C     1 
ATOM   5310 O  O     . ALA C 1 270 ? 89.408  90.281  129.221 1.00 108.39 ? 270 ALA B O     1 
ATOM   5311 C  CB    . ALA C 1 270 ? 89.418  93.031  127.524 1.00 101.37 ? 270 ALA B CB    1 
ATOM   5312 N  N     . PRO C 1 271 ? 90.190  89.893  127.154 1.00 109.12 ? 271 PRO B N     1 
ATOM   5313 C  CA    . PRO C 1 271 ? 90.958  88.727  127.631 1.00 106.22 ? 271 PRO B CA    1 
ATOM   5314 C  C     . PRO C 1 271 ? 92.012  89.084  128.665 1.00 107.42 ? 271 PRO B C     1 
ATOM   5315 O  O     . PRO C 1 271 ? 92.026  88.502  129.758 1.00 106.99 ? 271 PRO B O     1 
ATOM   5316 C  CB    . PRO C 1 271 ? 91.571  88.167  126.339 1.00 102.43 ? 271 PRO B CB    1 
ATOM   5317 C  CG    . PRO C 1 271 ? 91.614  89.324  125.403 1.00 106.79 ? 271 PRO B CG    1 
ATOM   5318 C  CD    . PRO C 1 271 ? 90.405  90.152  125.720 1.00 108.90 ? 271 PRO B CD    1 
ATOM   5319 N  N     . LYS C 1 272 ? 92.896  90.028  128.355 1.00 109.57 ? 272 LYS B N     1 
ATOM   5320 C  CA    . LYS C 1 272 ? 93.914  90.458  129.302 1.00 105.88 ? 272 LYS B CA    1 
ATOM   5321 C  C     . LYS C 1 272 ? 94.428  91.825  128.883 1.00 105.02 ? 272 LYS B C     1 
ATOM   5322 O  O     . LYS C 1 272 ? 94.243  92.256  127.742 1.00 103.68 ? 272 LYS B O     1 
ATOM   5323 C  CB    . LYS C 1 272 ? 95.066  89.450  129.391 1.00 103.75 ? 272 LYS B CB    1 
ATOM   5324 C  CG    . LYS C 1 272 ? 95.733  89.392  130.755 1.00 100.71 ? 272 LYS B CG    1 
ATOM   5325 C  CD    . LYS C 1 272 ? 97.055  88.646  130.694 1.00 106.91 ? 272 LYS B CD    1 
ATOM   5326 C  CE    . LYS C 1 272 ? 97.791  88.718  132.021 1.00 106.32 ? 272 LYS B CE    1 
ATOM   5327 N  NZ    . LYS C 1 272 ? 98.864  89.751  132.006 1.00 97.84  ? 272 LYS B NZ    1 
ATOM   5328 N  N     . VAL C 1 273 ? 95.077  92.501  129.826 1.00 100.51 ? 273 VAL B N     1 
ATOM   5329 C  CA    . VAL C 1 273 ? 95.697  93.798  129.588 1.00 95.90  ? 273 VAL B CA    1 
ATOM   5330 C  C     . VAL C 1 273 ? 97.193  93.637  129.800 1.00 93.15  ? 273 VAL B C     1 
ATOM   5331 O  O     . VAL C 1 273 ? 97.631  93.230  130.883 1.00 95.85  ? 273 VAL B O     1 
ATOM   5332 C  CB    . VAL C 1 273 ? 95.127  94.883  130.514 1.00 93.08  ? 273 VAL B CB    1 
ATOM   5333 C  CG1   . VAL C 1 273 ? 95.972  96.144  130.433 1.00 89.20  ? 273 VAL B CG1   1 
ATOM   5334 C  CG2   . VAL C 1 273 ? 93.684  95.174  130.156 1.00 93.89  ? 273 VAL B CG2   1 
ATOM   5335 N  N     . GLU C 1 274 ? 97.976  93.953  128.770 1.00 90.80  ? 274 GLU B N     1 
ATOM   5336 C  CA    . GLU C 1 274 ? 99.426  93.793  128.826 1.00 89.72  ? 274 GLU B CA    1 
ATOM   5337 C  C     . GLU C 1 274 ? 100.046 95.133  129.207 1.00 82.34  ? 274 GLU B C     1 
ATOM   5338 O  O     . GLU C 1 274 ? 100.587 95.864  128.379 1.00 85.79  ? 274 GLU B O     1 
ATOM   5339 C  CB    . GLU C 1 274 ? 99.960  93.276  127.498 1.00 93.51  ? 274 GLU B CB    1 
ATOM   5340 C  CG    . GLU C 1 274 ? 99.024  92.313  126.797 1.00 99.21  ? 274 GLU B CG    1 
ATOM   5341 C  CD    . GLU C 1 274 ? 99.204  90.878  127.253 1.00 107.43 ? 274 GLU B CD    1 
ATOM   5342 O  OE1   . GLU C 1 274 ? 99.963  90.645  128.215 1.00 102.71 ? 274 GLU B OE1   1 
ATOM   5343 O  OE2   . GLU C 1 274 ? 98.586  89.980  126.644 1.00 115.62 ? 274 GLU B OE2   1 
ATOM   5344 N  N     . PHE C 1 275 ? 99.958  95.453  130.493 1.00 71.96  ? 275 PHE B N     1 
ATOM   5345 C  CA    . PHE C 1 275 ? 100.578 96.654  131.034 1.00 65.61  ? 275 PHE B CA    1 
ATOM   5346 C  C     . PHE C 1 275 ? 102.026 96.331  131.375 1.00 63.85  ? 275 PHE B C     1 
ATOM   5347 O  O     . PHE C 1 275 ? 102.295 95.370  132.102 1.00 68.20  ? 275 PHE B O     1 
ATOM   5348 C  CB    . PHE C 1 275 ? 99.821  97.143  132.267 1.00 63.33  ? 275 PHE B CB    1 
ATOM   5349 C  CG    . PHE C 1 275 ? 100.114 98.569  132.635 1.00 63.36  ? 275 PHE B CG    1 
ATOM   5350 C  CD1   . PHE C 1 275 ? 101.320 98.918  133.214 1.00 63.29  ? 275 PHE B CD1   1 
ATOM   5351 C  CD2   . PHE C 1 275 ? 99.180  99.561  132.404 1.00 68.13  ? 275 PHE B CD2   1 
ATOM   5352 C  CE1   . PHE C 1 275 ? 101.590 100.225 133.553 1.00 59.43  ? 275 PHE B CE1   1 
ATOM   5353 C  CE2   . PHE C 1 275 ? 99.446  100.872 132.741 1.00 71.69  ? 275 PHE B CE2   1 
ATOM   5354 C  CZ    . PHE C 1 275 ? 100.653 101.203 133.316 1.00 65.59  ? 275 PHE B CZ    1 
ATOM   5355 N  N     . GLU C 1 276 ? 102.955 97.125  130.849 1.00 62.25  ? 276 GLU B N     1 
ATOM   5356 C  CA    . GLU C 1 276 ? 104.371 96.902  131.101 1.00 60.92  ? 276 GLU B CA    1 
ATOM   5357 C  C     . GLU C 1 276 ? 105.064 98.231  131.359 1.00 54.32  ? 276 GLU B C     1 
ATOM   5358 O  O     . GLU C 1 276 ? 104.628 99.282  130.884 1.00 60.31  ? 276 GLU B O     1 
ATOM   5359 C  CB    . GLU C 1 276 ? 105.039 96.157  129.939 1.00 63.60  ? 276 GLU B CB    1 
ATOM   5360 C  CG    . GLU C 1 276 ? 105.616 97.039  128.854 1.00 62.05  ? 276 GLU B CG    1 
ATOM   5361 C  CD    . GLU C 1 276 ? 106.493 96.262  127.894 1.00 74.44  ? 276 GLU B CD    1 
ATOM   5362 O  OE1   . GLU C 1 276 ? 106.383 95.019  127.864 1.00 84.30  ? 276 GLU B OE1   1 
ATOM   5363 O  OE2   . GLU C 1 276 ? 107.289 96.890  127.168 1.00 72.47  ? 276 GLU B OE2   1 
ATOM   5364 N  N     . VAL C 1 277 ? 106.151 98.166  132.124 1.00 47.87  ? 277 VAL B N     1 
ATOM   5365 C  CA    . VAL C 1 277 ? 106.889 99.339  132.578 1.00 47.19  ? 277 VAL B CA    1 
ATOM   5366 C  C     . VAL C 1 277 ? 108.255 99.336  131.911 1.00 45.97  ? 277 VAL B C     1 
ATOM   5367 O  O     . VAL C 1 277 ? 108.900 98.286  131.811 1.00 54.93  ? 277 VAL B O     1 
ATOM   5368 C  CB    . VAL C 1 277 ? 107.029 99.350  134.110 1.00 49.54  ? 277 VAL B CB    1 
ATOM   5369 C  CG1   . VAL C 1 277 ? 107.860 100.533 134.567 1.00 44.09  ? 277 VAL B CG1   1 
ATOM   5370 C  CG2   . VAL C 1 277 ? 105.663 99.369  134.764 1.00 54.32  ? 277 VAL B CG2   1 
ATOM   5371 N  N     . HIS C 1 278 ? 108.687 100.503 131.445 1.00 41.75  ? 278 HIS B N     1 
ATOM   5372 C  CA    . HIS C 1 278 ? 110.026 100.682 130.904 1.00 43.62  ? 278 HIS B CA    1 
ATOM   5373 C  C     . HIS C 1 278 ? 110.827 101.594 131.820 1.00 51.81  ? 278 HIS B C     1 
ATOM   5374 O  O     . HIS C 1 278 ? 110.308 102.597 132.319 1.00 58.85  ? 278 HIS B O     1 
ATOM   5375 C  CB    . HIS C 1 278 ? 109.986 101.270 129.494 1.00 44.88  ? 278 HIS B CB    1 
ATOM   5376 C  CG    . HIS C 1 278 ? 109.570 100.291 128.443 1.00 47.77  ? 278 HIS B CG    1 
ATOM   5377 N  ND1   . HIS C 1 278 ? 109.953 100.408 127.125 1.00 48.63  ? 278 HIS B ND1   1 
ATOM   5378 C  CD2   . HIS C 1 278 ? 108.802 99.179  128.514 1.00 48.05  ? 278 HIS B CD2   1 
ATOM   5379 C  CE1   . HIS C 1 278 ? 109.441 99.410  126.429 1.00 54.03  ? 278 HIS B CE1   1 
ATOM   5380 N  NE2   . HIS C 1 278 ? 108.737 98.650  127.249 1.00 54.76  ? 278 HIS B NE2   1 
ATOM   5381 N  N     . THR C 1 279 ? 112.090 101.242 132.041 1.00 48.83  ? 279 THR B N     1 
ATOM   5382 C  CA    . THR C 1 279 ? 112.949 102.019 132.919 1.00 50.70  ? 279 THR B CA    1 
ATOM   5383 C  C     . THR C 1 279 ? 114.376 101.926 132.412 1.00 55.71  ? 279 THR B C     1 
ATOM   5384 O  O     . THR C 1 279 ? 114.740 100.993 131.694 1.00 61.01  ? 279 THR B O     1 
ATOM   5385 C  CB    . THR C 1 279 ? 112.871 101.531 134.368 1.00 51.62  ? 279 THR B CB    1 
ATOM   5386 O  OG1   . THR C 1 279 ? 113.967 102.076 135.111 1.00 59.13  ? 279 THR B OG1   1 
ATOM   5387 C  CG2   . THR C 1 279 ? 112.942 100.022 134.421 1.00 51.41  ? 279 THR B CG2   1 
ATOM   5388 N  N     . LEU C 1 280 ? 115.187 102.906 132.797 1.00 54.45  ? 280 LEU B N     1 
ATOM   5389 C  CA    . LEU C 1 280 ? 116.577 102.954 132.368 1.00 54.32  ? 280 LEU B CA    1 
ATOM   5390 C  C     . LEU C 1 280 ? 117.552 102.516 133.449 1.00 62.09  ? 280 LEU B C     1 
ATOM   5391 O  O     . LEU C 1 280 ? 118.482 101.757 133.163 1.00 68.42  ? 280 LEU B O     1 
ATOM   5392 C  CB    . LEU C 1 280 ? 116.934 104.365 131.898 1.00 49.47  ? 280 LEU B CB    1 
ATOM   5393 C  CG    . LEU C 1 280 ? 117.211 104.474 130.401 1.00 51.67  ? 280 LEU B CG    1 
ATOM   5394 C  CD1   . LEU C 1 280 ? 115.981 104.088 129.620 1.00 52.45  ? 280 LEU B CD1   1 
ATOM   5395 C  CD2   . LEU C 1 280 ? 117.641 105.879 130.044 1.00 55.83  ? 280 LEU B CD2   1 
ATOM   5396 N  N     . ALA C 1 281 ? 117.362 102.969 134.685 1.00 56.30  ? 281 ALA B N     1 
ATOM   5397 C  CA    . ALA C 1 281 ? 118.259 102.647 135.794 1.00 58.34  ? 281 ALA B CA    1 
ATOM   5398 C  C     . ALA C 1 281 ? 117.437 102.168 136.981 1.00 58.72  ? 281 ALA B C     1 
ATOM   5399 O  O     . ALA C 1 281 ? 117.171 102.935 137.917 1.00 61.31  ? 281 ALA B O     1 
ATOM   5400 C  CB    . ALA C 1 281 ? 119.121 103.852 136.173 1.00 58.95  ? 281 ALA B CB    1 
ATOM   5401 N  N     . PRO C 1 282 ? 117.022 100.896 136.986 1.00 61.95  ? 282 PRO B N     1 
ATOM   5402 C  CA    . PRO C 1 282 ? 116.273 100.334 138.114 1.00 63.54  ? 282 PRO B CA    1 
ATOM   5403 C  C     . PRO C 1 282 ? 117.173 99.881  139.261 1.00 68.15  ? 282 PRO B C     1 
ATOM   5404 O  O     . PRO C 1 282 ? 117.022 98.787  139.803 1.00 69.89  ? 282 PRO B O     1 
ATOM   5405 C  CB    . PRO C 1 282 ? 115.540 99.150  137.470 1.00 64.17  ? 282 PRO B CB    1 
ATOM   5406 C  CG    . PRO C 1 282 ? 116.502 98.674  136.438 1.00 66.42  ? 282 PRO B CG    1 
ATOM   5407 C  CD    . PRO C 1 282 ? 117.251 99.893  135.932 1.00 63.25  ? 282 PRO B CD    1 
ATOM   5408 N  N     . GLU C 1 283 ? 118.124 100.734 139.627 1.00 71.29  ? 283 GLU B N     1 
ATOM   5409 C  CA    . GLU C 1 283 ? 119.056 100.447 140.705 1.00 68.86  ? 283 GLU B CA    1 
ATOM   5410 C  C     . GLU C 1 283 ? 118.560 101.059 142.008 1.00 69.27  ? 283 GLU B C     1 
ATOM   5411 O  O     . GLU C 1 283 ? 117.705 101.948 142.023 1.00 66.20  ? 283 GLU B O     1 
ATOM   5412 C  CB    . GLU C 1 283 ? 120.448 100.980 140.369 1.00 67.71  ? 283 GLU B CB    1 
ATOM   5413 C  CG    . GLU C 1 283 ? 121.251 100.072 139.456 1.00 77.64  ? 283 GLU B CG    1 
ATOM   5414 C  CD    . GLU C 1 283 ? 121.741 100.786 138.212 1.00 85.61  ? 283 GLU B CD    1 
ATOM   5415 O  OE1   . GLU C 1 283 ? 122.019 102.001 138.295 1.00 84.92  ? 283 GLU B OE1   1 
ATOM   5416 O  OE2   . GLU C 1 283 ? 121.846 100.135 137.152 1.00 87.88  ? 283 GLU B OE2   1 
ATOM   5417 N  N     . GLY C 1 284 ? 119.115 100.571 143.113 1.00 72.37  ? 284 GLY B N     1 
ATOM   5418 C  CA    . GLY C 1 284 ? 118.655 101.004 144.417 1.00 70.98  ? 284 GLY B CA    1 
ATOM   5419 C  C     . GLY C 1 284 ? 117.225 100.618 144.705 1.00 70.14  ? 284 GLY B C     1 
ATOM   5420 O  O     . GLY C 1 284 ? 116.550 101.295 145.486 1.00 73.22  ? 284 GLY B O     1 
ATOM   5421 N  N     . THR C 1 285 ? 116.743 99.545  144.087 1.00 65.80  ? 285 THR B N     1 
ATOM   5422 C  CA    . THR C 1 285 ? 115.363 99.113  144.249 1.00 65.16  ? 285 THR B CA    1 
ATOM   5423 C  C     . THR C 1 285 ? 115.279 97.631  143.923 1.00 65.05  ? 285 THR B C     1 
ATOM   5424 O  O     . THR C 1 285 ? 116.195 97.046  143.341 1.00 67.59  ? 285 THR B O     1 
ATOM   5425 C  CB    . THR C 1 285 ? 114.412 99.917  143.359 1.00 62.21  ? 285 THR B CB    1 
ATOM   5426 O  OG1   . THR C 1 285 ? 113.065 99.720  143.801 1.00 65.85  ? 285 THR B OG1   1 
ATOM   5427 C  CG2   . THR C 1 285 ? 114.531 99.469  141.914 1.00 64.38  ? 285 THR B CG2   1 
ATOM   5428 N  N     . ASN C 1 286 ? 114.162 97.028  144.312 1.00 67.71  ? 286 ASN B N     1 
ATOM   5429 C  CA    . ASN C 1 286 ? 113.881 95.622  144.055 1.00 70.52  ? 286 ASN B CA    1 
ATOM   5430 C  C     . ASN C 1 286 ? 112.703 95.474  143.098 1.00 72.37  ? 286 ASN B C     1 
ATOM   5431 O  O     . ASN C 1 286 ? 111.867 94.584  143.250 1.00 80.14  ? 286 ASN B O     1 
ATOM   5432 C  CB    . ASN C 1 286 ? 113.612 94.881  145.360 1.00 72.80  ? 286 ASN B CB    1 
ATOM   5433 C  CG    . ASN C 1 286 ? 114.005 93.424  145.293 1.00 74.73  ? 286 ASN B CG    1 
ATOM   5434 O  OD1   . ASN C 1 286 ? 114.442 92.935  144.253 1.00 78.81  ? 286 ASN B OD1   1 
ATOM   5435 N  ND2   . ASN C 1 286 ? 113.851 92.719  146.406 1.00 79.17  ? 286 ASN B ND2   1 
ATOM   5436 N  N     . ALA C 1 287 ? 112.634 96.356  142.096 1.00 67.44  ? 287 ALA B N     1 
ATOM   5437 C  CA    . ALA C 1 287 ? 111.469 96.409  141.218 1.00 67.70  ? 287 ALA B CA    1 
ATOM   5438 C  C     . ALA C 1 287 ? 111.271 95.111  140.448 1.00 73.81  ? 287 ALA B C     1 
ATOM   5439 O  O     . ALA C 1 287 ? 110.152 94.815  140.015 1.00 70.95  ? 287 ALA B O     1 
ATOM   5440 C  CB    . ALA C 1 287 ? 111.595 97.585  140.250 1.00 68.43  ? 287 ALA B CB    1 
ATOM   5441 N  N     . PHE C 1 288 ? 112.330 94.323  140.269 1.00 74.13  ? 288 PHE B N     1 
ATOM   5442 C  CA    . PHE C 1 288 ? 112.208 93.084  139.512 1.00 69.71  ? 288 PHE B CA    1 
ATOM   5443 C  C     . PHE C 1 288 ? 111.407 92.015  140.242 1.00 74.74  ? 288 PHE B C     1 
ATOM   5444 O  O     . PHE C 1 288 ? 110.980 91.047  139.604 1.00 74.24  ? 288 PHE B O     1 
ATOM   5445 C  CB    . PHE C 1 288 ? 113.593 92.543  139.165 1.00 66.90  ? 288 PHE B CB    1 
ATOM   5446 C  CG    . PHE C 1 288 ? 114.235 93.229  137.994 1.00 69.19  ? 288 PHE B CG    1 
ATOM   5447 C  CD1   . PHE C 1 288 ? 113.904 92.871  136.699 1.00 68.24  ? 288 PHE B CD1   1 
ATOM   5448 C  CD2   . PHE C 1 288 ? 115.172 94.229  138.188 1.00 72.38  ? 288 PHE B CD2   1 
ATOM   5449 C  CE1   . PHE C 1 288 ? 114.492 93.498  135.621 1.00 65.98  ? 288 PHE B CE1   1 
ATOM   5450 C  CE2   . PHE C 1 288 ? 115.764 94.859  137.112 1.00 73.91  ? 288 PHE B CE2   1 
ATOM   5451 C  CZ    . PHE C 1 288 ? 115.424 94.492  135.827 1.00 68.33  ? 288 PHE B CZ    1 
ATOM   5452 N  N     . VAL C 1 289 ? 111.192 92.158  141.548 1.00 77.52  ? 289 VAL B N     1 
ATOM   5453 C  CA    . VAL C 1 289 ? 110.435 91.171  142.306 1.00 77.35  ? 289 VAL B CA    1 
ATOM   5454 C  C     . VAL C 1 289 ? 109.198 91.752  142.977 1.00 75.76  ? 289 VAL B C     1 
ATOM   5455 O  O     . VAL C 1 289 ? 108.306 90.981  143.368 1.00 83.79  ? 289 VAL B O     1 
ATOM   5456 C  CB    . VAL C 1 289 ? 111.328 90.470  143.351 1.00 71.96  ? 289 VAL B CB    1 
ATOM   5457 C  CG1   . VAL C 1 289 ? 111.402 91.288  144.625 1.00 71.66  ? 289 VAL B CG1   1 
ATOM   5458 C  CG2   . VAL C 1 289 ? 110.822 89.065  143.636 1.00 70.36  ? 289 VAL B CG2   1 
ATOM   5459 N  N     . THR C 1 290 ? 109.090 93.071  143.128 1.00 67.60  ? 290 THR B N     1 
ATOM   5460 C  CA    . THR C 1 290 ? 107.871 93.678  143.644 1.00 69.77  ? 290 THR B CA    1 
ATOM   5461 C  C     . THR C 1 290 ? 106.912 94.085  142.538 1.00 73.68  ? 290 THR B C     1 
ATOM   5462 O  O     . THR C 1 290 ? 105.886 94.708  142.825 1.00 77.11  ? 290 THR B O     1 
ATOM   5463 C  CB    . THR C 1 290 ? 108.192 94.897  144.514 1.00 71.24  ? 290 THR B CB    1 
ATOM   5464 O  OG1   . THR C 1 290 ? 106.970 95.527  144.914 1.00 70.13  ? 290 THR B OG1   1 
ATOM   5465 C  CG2   . THR C 1 290 ? 109.015 95.897  143.742 1.00 72.91  ? 290 THR B CG2   1 
ATOM   5466 N  N     . TYR C 1 291 ? 107.226 93.760  141.286 1.00 72.41  ? 291 TYR B N     1 
ATOM   5467 C  CA    . TYR C 1 291 ? 106.316 93.965  140.171 1.00 73.51  ? 291 TYR B CA    1 
ATOM   5468 C  C     . TYR C 1 291 ? 105.581 92.690  139.790 1.00 81.29  ? 291 TYR B C     1 
ATOM   5469 O  O     . TYR C 1 291 ? 104.971 92.631  138.718 1.00 79.06  ? 291 TYR B O     1 
ATOM   5470 C  CB    . TYR C 1 291 ? 107.068 94.524  138.963 1.00 62.59  ? 291 TYR B CB    1 
ATOM   5471 C  CG    . TYR C 1 291 ? 107.001 96.027  138.872 1.00 60.53  ? 291 TYR B CG    1 
ATOM   5472 C  CD1   . TYR C 1 291 ? 105.781 96.682  138.880 1.00 60.45  ? 291 TYR B CD1   1 
ATOM   5473 C  CD2   . TYR C 1 291 ? 108.149 96.791  138.776 1.00 57.27  ? 291 TYR B CD2   1 
ATOM   5474 C  CE1   . TYR C 1 291 ? 105.706 98.053  138.797 1.00 54.45  ? 291 TYR B CE1   1 
ATOM   5475 C  CE2   . TYR C 1 291 ? 108.084 98.166  138.693 1.00 56.26  ? 291 TYR B CE2   1 
ATOM   5476 C  CZ    . TYR C 1 291 ? 106.860 98.789  138.704 1.00 55.47  ? 291 TYR B CZ    1 
ATOM   5477 O  OH    . TYR C 1 291 ? 106.788 100.158 138.621 1.00 65.97  ? 291 TYR B OH    1 
ATOM   5478 N  N     . GLU C 1 292 ? 105.631 91.668  140.644 1.00 84.02  ? 292 GLU B N     1 
ATOM   5479 C  CA    . GLU C 1 292 ? 104.845 90.453  140.481 1.00 83.37  ? 292 GLU B CA    1 
ATOM   5480 C  C     . GLU C 1 292 ? 103.524 90.519  141.232 1.00 87.62  ? 292 GLU B C     1 
ATOM   5481 O  O     . GLU C 1 292 ? 103.001 89.481  141.657 1.00 95.39  ? 292 GLU B O     1 
ATOM   5482 C  CB    . GLU C 1 292 ? 105.655 89.240  140.941 1.00 80.69  ? 292 GLU B CB    1 
ATOM   5483 C  CG    . GLU C 1 292 ? 106.883 88.956  140.098 1.00 85.12  ? 292 GLU B CG    1 
ATOM   5484 C  CD    . GLU C 1 292 ? 107.810 87.947  140.746 1.00 95.22  ? 292 GLU B CD    1 
ATOM   5485 O  OE1   . GLU C 1 292 ? 107.612 87.637  141.938 1.00 98.38  ? 292 GLU B OE1   1 
ATOM   5486 O  OE2   . GLU C 1 292 ? 108.738 87.466  140.064 1.00 96.88  ? 292 GLU B OE2   1 
ATOM   5487 N  N     . ALA C 1 293 ? 102.973 91.717  141.408 1.00 76.55  ? 293 ALA B N     1 
ATOM   5488 C  CA    . ALA C 1 293 ? 101.791 91.899  142.232 1.00 76.39  ? 293 ALA B CA    1 
ATOM   5489 C  C     . ALA C 1 293 ? 100.562 91.278  141.576 1.00 82.53  ? 293 ALA B C     1 
ATOM   5490 O  O     . ALA C 1 293 ? 100.506 91.064  140.363 1.00 90.04  ? 293 ALA B O     1 
ATOM   5491 C  CB    . ALA C 1 293 ? 101.547 93.383  142.497 1.00 75.69  ? 293 ALA B CB    1 
ATOM   5492 N  N     . ALA C 1 294 ? 99.567  90.988  142.407 1.00 80.46  ? 294 ALA B N     1 
ATOM   5493 C  CA    . ALA C 1 294 ? 98.298  90.438  141.951 1.00 85.56  ? 294 ALA B CA    1 
ATOM   5494 C  C     . ALA C 1 294 ? 97.386  91.576  141.498 1.00 92.42  ? 294 ALA B C     1 
ATOM   5495 O  O     . ALA C 1 294 ? 97.818  92.715  141.302 1.00 92.24  ? 294 ALA B O     1 
ATOM   5496 C  CB    . ALA C 1 294 ? 97.664  89.591  143.049 1.00 92.34  ? 294 ALA B CB    1 
ATOM   5497 N  N     . SER C 1 295 ? 96.106  91.276  141.314 1.00 96.95  ? 295 SER B N     1 
ATOM   5498 C  CA    . SER C 1 295 ? 95.142  92.252  140.818 1.00 99.63  ? 295 SER B CA    1 
ATOM   5499 C  C     . SER C 1 295 ? 93.846  92.077  141.605 1.00 110.89 ? 295 SER B C     1 
ATOM   5500 O  O     . SER C 1 295 ? 93.820  91.451  142.670 1.00 110.88 ? 295 SER B O     1 
ATOM   5501 C  CB    . SER C 1 295 ? 94.954  92.098  139.302 1.00 100.47 ? 295 SER B CB    1 
ATOM   5502 O  OG    . SER C 1 295 ? 96.203  92.114  138.634 1.00 93.17  ? 295 SER B OG    1 
ATOM   5503 N  N     . LEU C 1 296 ? 92.757  92.657  141.090 1.00 117.39 ? 296 LEU B N     1 
ATOM   5504 C  CA    . LEU C 1 296 ? 91.460  92.566  141.754 1.00 116.92 ? 296 LEU B CA    1 
ATOM   5505 C  C     . LEU C 1 296 ? 90.987  91.127  141.922 1.00 122.61 ? 296 LEU B C     1 
ATOM   5506 O  O     . LEU C 1 296 ? 90.090  90.877  142.733 1.00 119.03 ? 296 LEU B O     1 
ATOM   5507 C  CB    . LEU C 1 296 ? 90.413  93.358  140.970 1.00 113.36 ? 296 LEU B CB    1 
ATOM   5508 C  CG    . LEU C 1 296 ? 89.970  92.745  139.638 1.00 113.56 ? 296 LEU B CG    1 
ATOM   5509 C  CD1   . LEU C 1 296 ? 88.478  92.940  139.425 1.00 115.96 ? 296 LEU B CD1   1 
ATOM   5510 C  CD2   . LEU C 1 296 ? 90.760  93.327  138.476 1.00 99.12  ? 296 LEU B CD2   1 
ATOM   5511 N  N     . TYR C 1 297 ? 91.513  90.197  141.120 1.00 125.42 ? 297 TYR B N     1 
ATOM   5512 C  CA    . TYR C 1 297 ? 91.315  88.754  141.250 1.00 128.55 ? 297 TYR B CA    1 
ATOM   5513 C  C     . TYR C 1 297 ? 89.848  88.344  141.141 1.00 135.21 ? 297 TYR B C     1 
ATOM   5514 O  O     . TYR C 1 297 ? 89.523  87.162  141.293 1.00 135.77 ? 297 TYR B O     1 
ATOM   5515 C  CB    . TYR C 1 297 ? 91.953  88.220  142.549 1.00 128.06 ? 297 TYR B CB    1 
ATOM   5516 C  CG    . TYR C 1 297 ? 91.250  88.525  143.862 1.00 126.28 ? 297 TYR B CG    1 
ATOM   5517 C  CD1   . TYR C 1 297 ? 90.090  87.857  144.235 1.00 126.66 ? 297 TYR B CD1   1 
ATOM   5518 C  CD2   . TYR C 1 297 ? 91.777  89.456  144.749 1.00 119.55 ? 297 TYR B CD2   1 
ATOM   5519 C  CE1   . TYR C 1 297 ? 89.459  88.130  145.432 1.00 122.86 ? 297 TYR B CE1   1 
ATOM   5520 C  CE2   . TYR C 1 297 ? 91.151  89.735  145.948 1.00 116.51 ? 297 TYR B CE2   1 
ATOM   5521 C  CZ    . TYR C 1 297 ? 89.994  89.068  146.285 1.00 117.00 ? 297 TYR B CZ    1 
ATOM   5522 O  OH    . TYR C 1 297 ? 89.369  89.339  147.480 1.00 106.24 ? 297 TYR B OH    1 
ATOM   5523 N  N     . GLY C 1 298 ? 88.962  89.297  140.859 1.00 135.92 ? 298 GLY B N     1 
ATOM   5524 C  CA    . GLY C 1 298 ? 87.558  88.991  140.662 1.00 136.91 ? 298 GLY B CA    1 
ATOM   5525 C  C     . GLY C 1 298 ? 86.890  88.376  141.874 1.00 137.76 ? 298 GLY B C     1 
ATOM   5526 O  O     . GLY C 1 298 ? 86.623  89.064  142.864 1.00 135.71 ? 298 GLY B O     1 
ATOM   5527 N  N     . LEU C 1 299 ? 86.601  87.081  141.791 1.00 140.35 ? 299 LEU B N     1 
ATOM   5528 C  CA    . LEU C 1 299 ? 85.984  86.335  142.884 1.00 140.71 ? 299 LEU B CA    1 
ATOM   5529 C  C     . LEU C 1 299 ? 86.770  86.453  144.188 1.00 135.16 ? 299 LEU B C     1 
ATOM   5530 O  O     . LEU C 1 299 ? 86.189  86.610  145.262 1.00 130.96 ? 299 LEU B O     1 
ATOM   5531 C  CB    . LEU C 1 299 ? 85.830  84.862  142.483 1.00 138.18 ? 299 LEU B CB    1 
ATOM   5532 C  CG    . LEU C 1 299 ? 87.057  84.099  141.960 1.00 134.37 ? 299 LEU B CG    1 
ATOM   5533 C  CD1   . LEU C 1 299 ? 87.985  83.621  143.075 1.00 129.11 ? 299 LEU B CD1   1 
ATOM   5534 C  CD2   . LEU C 1 299 ? 86.624  82.931  141.083 1.00 131.86 ? 299 LEU B CD2   1 
ATOM   5535 N  N     . SER C 1 304 ? 92.110  81.553  139.725 1.00 124.11 ? 304 SER B N     1 
ATOM   5536 C  CA    . SER C 1 304 ? 91.326  81.504  138.497 1.00 134.39 ? 304 SER B CA    1 
ATOM   5537 C  C     . SER C 1 304 ? 91.655  82.686  137.592 1.00 131.84 ? 304 SER B C     1 
ATOM   5538 O  O     . SER C 1 304 ? 92.333  82.534  136.576 1.00 128.49 ? 304 SER B O     1 
ATOM   5539 C  CB    . SER C 1 304 ? 89.830  81.487  138.816 1.00 136.04 ? 304 SER B CB    1 
ATOM   5540 O  OG    . SER C 1 304 ? 89.345  82.795  139.064 1.00 133.59 ? 304 SER B OG    1 
ATOM   5541 N  N     . ALA C 1 305 ? 91.169  83.867  137.972 1.00 132.48 ? 305 ALA B N     1 
ATOM   5542 C  CA    . ALA C 1 305 ? 91.379  85.092  137.212 1.00 126.66 ? 305 ALA B CA    1 
ATOM   5543 C  C     . ALA C 1 305 ? 92.516  85.936  137.780 1.00 121.76 ? 305 ALA B C     1 
ATOM   5544 O  O     . ALA C 1 305 ? 92.472  87.169  137.703 1.00 118.60 ? 305 ALA B O     1 
ATOM   5545 C  CB    . ALA C 1 305 ? 90.088  85.908  137.154 1.00 122.79 ? 305 ALA B CB    1 
ATOM   5546 N  N     . VAL C 1 306 ? 93.532  85.296  138.353 1.00 116.87 ? 306 VAL B N     1 
ATOM   5547 C  CA    . VAL C 1 306 ? 94.665  85.993  138.951 1.00 109.30 ? 306 VAL B CA    1 
ATOM   5548 C  C     . VAL C 1 306 ? 95.818  86.005  137.957 1.00 101.75 ? 306 VAL B C     1 
ATOM   5549 O  O     . VAL C 1 306 ? 96.011  85.050  137.192 1.00 105.62 ? 306 VAL B O     1 
ATOM   5550 C  CB    . VAL C 1 306 ? 95.074  85.348  140.291 1.00 103.72 ? 306 VAL B CB    1 
ATOM   5551 C  CG1   . VAL C 1 306 ? 95.948  84.120  140.075 1.00 96.87  ? 306 VAL B CG1   1 
ATOM   5552 C  CG2   . VAL C 1 306 ? 95.784  86.363  141.172 1.00 104.43 ? 306 VAL B CG2   1 
ATOM   5553 N  N     . HIS C 1 307 ? 96.563  87.106  137.942 1.00 97.95  ? 307 HIS B N     1 
ATOM   5554 C  CA    . HIS C 1 307 ? 97.686  87.283  137.031 1.00 92.12  ? 307 HIS B CA    1 
ATOM   5555 C  C     . HIS C 1 307 ? 98.495  88.478  137.514 1.00 93.09  ? 307 HIS B C     1 
ATOM   5556 O  O     . HIS C 1 307 ? 98.064  89.229  138.393 1.00 94.19  ? 307 HIS B O     1 
ATOM   5557 C  CB    . HIS C 1 307 ? 97.219  87.484  135.587 1.00 90.96  ? 307 HIS B CB    1 
ATOM   5558 C  CG    . HIS C 1 307 ? 96.142  88.513  135.437 1.00 97.43  ? 307 HIS B CG    1 
ATOM   5559 N  ND1   . HIS C 1 307 ? 94.803  88.212  135.565 1.00 105.66 ? 307 HIS B ND1   1 
ATOM   5560 C  CD2   . HIS C 1 307 ? 96.206  89.838  135.167 1.00 95.47  ? 307 HIS B CD2   1 
ATOM   5561 C  CE1   . HIS C 1 307 ? 94.089  89.308  135.382 1.00 104.94 ? 307 HIS B CE1   1 
ATOM   5562 N  NE2   . HIS C 1 307 ? 94.916  90.309  135.139 1.00 98.39  ? 307 HIS B NE2   1 
ATOM   5563 N  N     . ARG C 1 308 ? 99.678  88.642  136.930 1.00 89.06  ? 308 ARG B N     1 
ATOM   5564 C  CA    . ARG C 1 308 ? 100.533 89.764  137.286 1.00 79.60  ? 308 ARG B CA    1 
ATOM   5565 C  C     . ARG C 1 308 ? 99.894  91.077  136.854 1.00 80.49  ? 308 ARG B C     1 
ATOM   5566 O  O     . ARG C 1 308 ? 99.385  91.200  135.736 1.00 82.74  ? 308 ARG B O     1 
ATOM   5567 C  CB    . ARG C 1 308 ? 101.907 89.614  136.636 1.00 74.63  ? 308 ARG B CB    1 
ATOM   5568 C  CG    . ARG C 1 308 ? 102.632 88.331  136.996 1.00 78.86  ? 308 ARG B CG    1 
ATOM   5569 C  CD    . ARG C 1 308 ? 104.016 88.290  136.371 1.00 82.28  ? 308 ARG B CD    1 
ATOM   5570 N  NE    . ARG C 1 308 ? 104.926 89.233  137.010 1.00 84.73  ? 308 ARG B NE    1 
ATOM   5571 C  CZ    . ARG C 1 308 ? 105.755 90.035  136.356 1.00 83.35  ? 308 ARG B CZ    1 
ATOM   5572 N  NH1   . ARG C 1 308 ? 105.817 90.035  135.034 1.00 79.92  ? 308 ARG B NH1   1 
ATOM   5573 N  NH2   . ARG C 1 308 ? 106.541 90.857  137.044 1.00 83.13  ? 308 ARG B NH2   1 
ATOM   5574 N  N     . ALA C 1 309 ? 99.917  92.062  137.753 1.00 80.40  ? 309 ALA B N     1 
ATOM   5575 C  CA    . ALA C 1 309 ? 99.401  93.382  137.410 1.00 75.91  ? 309 ALA B CA    1 
ATOM   5576 C  C     . ALA C 1 309 ? 100.246 94.035  136.325 1.00 71.73  ? 309 ALA B C     1 
ATOM   5577 O  O     . ALA C 1 309 ? 99.710  94.674  135.413 1.00 77.01  ? 309 ALA B O     1 
ATOM   5578 C  CB    . ALA C 1 309 ? 99.347  94.267  138.654 1.00 72.53  ? 309 ALA B CB    1 
ATOM   5579 N  N     . ILE C 1 310 ? 101.564 93.883  136.408 1.00 66.51  ? 310 ILE B N     1 
ATOM   5580 C  CA    . ILE C 1 310 ? 102.494 94.401  135.413 1.00 61.83  ? 310 ILE B CA    1 
ATOM   5581 C  C     . ILE C 1 310 ? 103.066 93.211  134.659 1.00 71.37  ? 310 ILE B C     1 
ATOM   5582 O  O     . ILE C 1 310 ? 103.631 92.295  135.269 1.00 74.16  ? 310 ILE B O     1 
ATOM   5583 C  CB    . ILE C 1 310 ? 103.607 95.233  136.063 1.00 58.71  ? 310 ILE B CB    1 
ATOM   5584 C  CG1   . ILE C 1 310 ? 103.002 96.349  136.915 1.00 58.18  ? 310 ILE B CG1   1 
ATOM   5585 C  CG2   . ILE C 1 310 ? 104.536 95.797  135.006 1.00 59.19  ? 310 ILE B CG2   1 
ATOM   5586 C  CD1   . ILE C 1 310 ? 102.592 97.564  136.134 1.00 59.90  ? 310 ILE B CD1   1 
ATOM   5587 N  N     . ARG C 1 311 ? 102.912 93.218  133.333 1.00 74.21  ? 311 ARG B N     1 
ATOM   5588 C  CA    . ARG C 1 311 ? 103.342 92.075  132.533 1.00 72.67  ? 311 ARG B CA    1 
ATOM   5589 C  C     . ARG C 1 311 ? 104.848 91.865  132.627 1.00 68.97  ? 311 ARG B C     1 
ATOM   5590 O  O     . ARG C 1 311 ? 105.319 90.739  132.821 1.00 68.67  ? 311 ARG B O     1 
ATOM   5591 C  CB    . ARG C 1 311 ? 102.920 92.266  131.077 1.00 80.13  ? 311 ARG B CB    1 
ATOM   5592 C  CG    . ARG C 1 311 ? 103.656 91.364  130.104 1.00 80.37  ? 311 ARG B CG    1 
ATOM   5593 C  CD    . ARG C 1 311 ? 103.017 91.388  128.729 1.00 84.66  ? 311 ARG B CD    1 
ATOM   5594 N  NE    . ARG C 1 311 ? 103.942 90.955  127.690 1.00 90.45  ? 311 ARG B NE    1 
ATOM   5595 C  CZ    . ARG C 1 311 ? 104.906 91.710  127.181 1.00 90.17  ? 311 ARG B CZ    1 
ATOM   5596 N  NH1   . ARG C 1 311 ? 105.097 92.954  127.589 1.00 88.29  ? 311 ARG B NH1   1 
ATOM   5597 N  NH2   . ARG C 1 311 ? 105.695 91.205  126.237 1.00 89.06  ? 311 ARG B NH2   1 
ATOM   5598 N  N     . GLU C 1 312 ? 105.621 92.940  132.498 1.00 68.89  ? 312 GLU B N     1 
ATOM   5599 C  CA    . GLU C 1 312 ? 107.072 92.832  132.528 1.00 70.62  ? 312 GLU B CA    1 
ATOM   5600 C  C     . GLU C 1 312 ? 107.667 94.202  132.810 1.00 62.03  ? 312 GLU B C     1 
ATOM   5601 O  O     . GLU C 1 312 ? 107.005 95.231  132.662 1.00 63.17  ? 312 GLU B O     1 
ATOM   5602 C  CB    . GLU C 1 312 ? 107.621 92.273  131.211 1.00 76.88  ? 312 GLU B CB    1 
ATOM   5603 C  CG    . GLU C 1 312 ? 108.902 91.467  131.356 1.00 79.21  ? 312 GLU B CG    1 
ATOM   5604 C  CD    . GLU C 1 312 ? 109.622 91.274  130.035 1.00 88.20  ? 312 GLU B CD    1 
ATOM   5605 O  OE1   . GLU C 1 312 ? 109.325 92.022  129.079 1.00 87.98  ? 312 GLU B OE1   1 
ATOM   5606 O  OE2   . GLU C 1 312 ? 110.487 90.378  129.952 1.00 91.23  ? 312 GLU B OE2   1 
ATOM   5607 N  N     . LEU C 1 313 ? 108.930 94.195  133.223 1.00 56.40  ? 313 LEU B N     1 
ATOM   5608 C  CA    . LEU C 1 313 ? 109.729 95.402  133.365 1.00 51.97  ? 313 LEU B CA    1 
ATOM   5609 C  C     . LEU C 1 313 ? 110.893 95.318  132.392 1.00 51.70  ? 313 LEU B C     1 
ATOM   5610 O  O     . LEU C 1 313 ? 111.637 94.332  132.395 1.00 63.06  ? 313 LEU B O     1 
ATOM   5611 C  CB    . LEU C 1 313 ? 110.241 95.566  134.798 1.00 53.05  ? 313 LEU B CB    1 
ATOM   5612 C  CG    . LEU C 1 313 ? 111.083 96.811  135.082 1.00 46.31  ? 313 LEU B CG    1 
ATOM   5613 C  CD1   . LEU C 1 313 ? 110.611 97.489  136.343 1.00 46.43  ? 313 LEU B CD1   1 
ATOM   5614 C  CD2   . LEU C 1 313 ? 112.544 96.450  135.203 1.00 53.78  ? 313 LEU B CD2   1 
ATOM   5615 N  N     . TYR C 1 314 ? 111.048 96.342  131.562 1.00 47.90  ? 314 TYR B N     1 
ATOM   5616 C  CA    . TYR C 1 314 ? 112.085 96.359  130.546 1.00 50.68  ? 314 TYR B CA    1 
ATOM   5617 C  C     . TYR C 1 314 ? 113.113 97.437  130.857 1.00 57.13  ? 314 TYR B C     1 
ATOM   5618 O  O     . TYR C 1 314 ? 112.787 98.491  131.409 1.00 62.74  ? 314 TYR B O     1 
ATOM   5619 C  CB    . TYR C 1 314 ? 111.494 96.593  129.154 1.00 56.51  ? 314 TYR B CB    1 
ATOM   5620 C  CG    . TYR C 1 314 ? 112.457 96.285  128.033 1.00 56.18  ? 314 TYR B CG    1 
ATOM   5621 C  CD1   . TYR C 1 314 ? 113.164 95.093  128.011 1.00 60.19  ? 314 TYR B CD1   1 
ATOM   5622 C  CD2   . TYR C 1 314 ? 112.665 97.187  127.001 1.00 56.13  ? 314 TYR B CD2   1 
ATOM   5623 C  CE1   . TYR C 1 314 ? 114.047 94.806  126.992 1.00 66.34  ? 314 TYR B CE1   1 
ATOM   5624 C  CE2   . TYR C 1 314 ? 113.546 96.909  125.979 1.00 61.55  ? 314 TYR B CE2   1 
ATOM   5625 C  CZ    . TYR C 1 314 ? 114.235 95.717  125.979 1.00 69.44  ? 314 TYR B CZ    1 
ATOM   5626 O  OH    . TYR C 1 314 ? 115.115 95.435  124.961 1.00 76.14  ? 314 TYR B OH    1 
ATOM   5627 N  N     . VAL C 1 315 ? 114.365 97.141  130.525 1.00 54.83  ? 315 VAL B N     1 
ATOM   5628 C  CA    . VAL C 1 315 ? 115.469 98.090  130.648 1.00 54.96  ? 315 VAL B CA    1 
ATOM   5629 C  C     . VAL C 1 315 ? 116.225 98.091  129.326 1.00 58.44  ? 315 VAL B C     1 
ATOM   5630 O  O     . VAL C 1 315 ? 117.128 97.264  129.132 1.00 68.31  ? 315 VAL B O     1 
ATOM   5631 C  CB    . VAL C 1 315 ? 116.395 97.734  131.821 1.00 57.05  ? 315 VAL B CB    1 
ATOM   5632 C  CG1   . VAL C 1 315 ? 117.495 98.775  131.961 1.00 58.11  ? 315 VAL B CG1   1 
ATOM   5633 C  CG2   . VAL C 1 315 ? 115.603 97.614  133.109 1.00 55.44  ? 315 VAL B CG2   1 
ATOM   5634 N  N     . PRO C 1 316 ? 115.893 98.979  128.395 1.00 54.13  ? 316 PRO B N     1 
ATOM   5635 C  CA    . PRO C 1 316 ? 116.505 98.931  127.064 1.00 58.58  ? 316 PRO B CA    1 
ATOM   5636 C  C     . PRO C 1 316 ? 117.992 99.219  127.133 1.00 63.00  ? 316 PRO B C     1 
ATOM   5637 O  O     . PRO C 1 316 ? 118.405 100.308 127.560 1.00 68.53  ? 316 PRO B O     1 
ATOM   5638 C  CB    . PRO C 1 316 ? 115.761 100.031 126.290 1.00 59.27  ? 316 PRO B CB    1 
ATOM   5639 C  CG    . PRO C 1 316 ? 114.560 100.360 127.115 1.00 60.11  ? 316 PRO B CG    1 
ATOM   5640 C  CD    . PRO C 1 316 ? 114.944 100.092 128.525 1.00 57.85  ? 316 PRO B CD    1 
ATOM   5641 N  N     . PRO C 1 317 ? 118.833 98.266  126.727 1.00 60.48  ? 317 PRO B N     1 
ATOM   5642 C  CA    . PRO C 1 317 ? 120.281 98.510  126.732 1.00 61.89  ? 317 PRO B CA    1 
ATOM   5643 C  C     . PRO C 1 317 ? 120.674 99.571  125.719 1.00 64.70  ? 317 PRO B C     1 
ATOM   5644 O  O     . PRO C 1 317 ? 121.385 100.525 126.046 1.00 66.15  ? 317 PRO B O     1 
ATOM   5645 C  CB    . PRO C 1 317 ? 120.874 97.139  126.374 1.00 64.57  ? 317 PRO B CB    1 
ATOM   5646 C  CG    . PRO C 1 317 ? 119.757 96.156  126.570 1.00 68.32  ? 317 PRO B CG    1 
ATOM   5647 C  CD    . PRO C 1 317 ? 118.504 96.906  126.275 1.00 64.88  ? 317 PRO B CD    1 
ATOM   5648 N  N     . THR C 1 318 ? 120.213 99.409  124.485 1.00 61.02  ? 318 THR B N     1 
ATOM   5649 C  CA    . THR C 1 318 ? 120.452 100.351 123.403 1.00 58.55  ? 318 THR B CA    1 
ATOM   5650 C  C     . THR C 1 318 ? 119.116 100.861 122.874 1.00 60.00  ? 318 THR B C     1 
ATOM   5651 O  O     . THR C 1 318 ? 118.045 100.434 123.308 1.00 69.50  ? 318 THR B O     1 
ATOM   5652 C  CB    . THR C 1 318 ? 121.262 99.706  122.275 1.00 60.35  ? 318 THR B CB    1 
ATOM   5653 O  OG1   . THR C 1 318 ? 120.369 99.097  121.337 1.00 65.57  ? 318 THR B OG1   1 
ATOM   5654 C  CG2   . THR C 1 318 ? 122.204 98.646  122.825 1.00 61.14  ? 318 THR B CG2   1 
ATOM   5655 N  N     . ALA C 1 319 ? 119.186 101.791 121.921 1.00 57.92  ? 319 ALA B N     1 
ATOM   5656 C  CA    . ALA C 1 319 ? 117.972 102.306 121.302 1.00 55.92  ? 319 ALA B CA    1 
ATOM   5657 C  C     . ALA C 1 319 ? 117.363 101.312 120.323 1.00 57.82  ? 319 ALA B C     1 
ATOM   5658 O  O     . ALA C 1 319 ? 116.141 101.294 120.143 1.00 56.16  ? 319 ALA B O     1 
ATOM   5659 C  CB    . ALA C 1 319 ? 118.262 103.628 120.595 1.00 60.55  ? 319 ALA B CB    1 
ATOM   5660 N  N     . ALA C 1 320 ? 118.192 100.489 119.679 1.00 61.04  ? 320 ALA B N     1 
ATOM   5661 C  CA    . ALA C 1 320 ? 117.696 99.485  118.747 1.00 61.63  ? 320 ALA B CA    1 
ATOM   5662 C  C     . ALA C 1 320 ? 117.090 98.278  119.449 1.00 69.53  ? 320 ALA B C     1 
ATOM   5663 O  O     . ALA C 1 320 ? 116.254 97.587  118.854 1.00 77.08  ? 320 ALA B O     1 
ATOM   5664 C  CB    . ALA C 1 320 ? 118.822 99.028  117.819 1.00 62.62  ? 320 ALA B CB    1 
ATOM   5665 N  N     . ASP C 1 321 ? 117.504 98.000  120.687 1.00 67.40  ? 321 ASP B N     1 
ATOM   5666 C  CA    . ASP C 1 321 ? 116.944 96.866  121.414 1.00 66.00  ? 321 ASP B CA    1 
ATOM   5667 C  C     . ASP C 1 321 ? 115.464 97.073  121.702 1.00 66.10  ? 321 ASP B C     1 
ATOM   5668 O  O     . ASP C 1 321 ? 114.680 96.118  121.668 1.00 70.25  ? 321 ASP B O     1 
ATOM   5669 C  CB    . ASP C 1 321 ? 117.717 96.637  122.709 1.00 64.50  ? 321 ASP B CB    1 
ATOM   5670 C  CG    . ASP C 1 321 ? 117.856 95.170  123.051 1.00 75.87  ? 321 ASP B CG    1 
ATOM   5671 O  OD1   . ASP C 1 321 ? 116.914 94.606  123.644 1.00 75.61  ? 321 ASP B OD1   1 
ATOM   5672 O  OD2   . ASP C 1 321 ? 118.906 94.579  122.724 1.00 84.22  ? 321 ASP B OD2   1 
ATOM   5673 N  N     . LEU C 1 322 ? 115.062 98.313  121.989 1.00 59.97  ? 322 LEU B N     1 
ATOM   5674 C  CA    . LEU C 1 322 ? 113.646 98.605  122.181 1.00 60.96  ? 322 LEU B CA    1 
ATOM   5675 C  C     . LEU C 1 322 ? 112.849 98.317  120.914 1.00 68.51  ? 322 LEU B C     1 
ATOM   5676 O  O     . LEU C 1 322 ? 111.769 97.718  120.973 1.00 75.33  ? 322 LEU B O     1 
ATOM   5677 C  CB    . LEU C 1 322 ? 113.471 100.061 122.609 1.00 55.49  ? 322 LEU B CB    1 
ATOM   5678 C  CG    . LEU C 1 322 ? 112.074 100.670 122.502 1.00 52.11  ? 322 LEU B CG    1 
ATOM   5679 C  CD1   . LEU C 1 322 ? 111.085 99.902  123.357 1.00 56.64  ? 322 LEU B CD1   1 
ATOM   5680 C  CD2   . LEU C 1 322 ? 112.113 102.129 122.910 1.00 49.77  ? 322 LEU B CD2   1 
ATOM   5681 N  N     . ALA C 1 323 ? 113.373 98.729  119.757 1.00 63.97  ? 323 ALA B N     1 
ATOM   5682 C  CA    . ALA C 1 323 ? 112.690 98.459  118.497 1.00 59.56  ? 323 ALA B CA    1 
ATOM   5683 C  C     . ALA C 1 323 ? 112.602 96.964  118.226 1.00 64.51  ? 323 ALA B C     1 
ATOM   5684 O  O     . ALA C 1 323 ? 111.560 96.464  117.782 1.00 68.01  ? 323 ALA B O     1 
ATOM   5685 C  CB    . ALA C 1 323 ? 113.411 99.169  117.353 1.00 64.47  ? 323 ALA B CB    1 
ATOM   5686 N  N     . ARG C 1 324 ? 113.689 96.233  118.483 1.00 65.12  ? 324 ARG B N     1 
ATOM   5687 C  CA    . ARG C 1 324 ? 113.678 94.790  118.265 1.00 69.28  ? 324 ARG B CA    1 
ATOM   5688 C  C     . ARG C 1 324 ? 112.667 94.102  119.174 1.00 72.98  ? 324 ARG B C     1 
ATOM   5689 O  O     . ARG C 1 324 ? 111.929 93.209  118.736 1.00 78.50  ? 324 ARG B O     1 
ATOM   5690 C  CB    . ARG C 1 324 ? 115.076 94.215  118.485 1.00 68.35  ? 324 ARG B CB    1 
ATOM   5691 C  CG    . ARG C 1 324 ? 115.987 94.329  117.276 1.00 75.99  ? 324 ARG B CG    1 
ATOM   5692 C  CD    . ARG C 1 324 ? 117.303 93.607  117.500 1.00 83.44  ? 324 ARG B CD    1 
ATOM   5693 N  NE    . ARG C 1 324 ? 118.360 94.518  117.921 1.00 93.63  ? 324 ARG B NE    1 
ATOM   5694 C  CZ    . ARG C 1 324 ? 119.293 95.008  117.116 1.00 96.58  ? 324 ARG B CZ    1 
ATOM   5695 N  NH1   . ARG C 1 324 ? 119.329 94.698  115.830 1.00 96.75  ? 324 ARG B NH1   1 
ATOM   5696 N  NH2   . ARG C 1 324 ? 120.213 95.830  117.612 1.00 88.32  ? 324 ARG B NH2   1 
ATOM   5697 N  N     . ARG C 1 325 ? 112.615 94.506  120.446 1.00 68.59  ? 325 ARG B N     1 
ATOM   5698 C  CA    . ARG C 1 325 ? 111.653 93.917  121.370 1.00 69.32  ? 325 ARG B CA    1 
ATOM   5699 C  C     . ARG C 1 325 ? 110.224 94.236  120.956 1.00 72.53  ? 325 ARG B C     1 
ATOM   5700 O  O     . ARG C 1 325 ? 109.339 93.379  121.052 1.00 82.33  ? 325 ARG B O     1 
ATOM   5701 C  CB    . ARG C 1 325 ? 111.914 94.405  122.792 1.00 67.43  ? 325 ARG B CB    1 
ATOM   5702 C  CG    . ARG C 1 325 ? 110.988 93.787  123.823 1.00 69.92  ? 325 ARG B CG    1 
ATOM   5703 C  CD    . ARG C 1 325 ? 110.981 94.585  125.112 1.00 72.52  ? 325 ARG B CD    1 
ATOM   5704 N  NE    . ARG C 1 325 ? 110.257 93.898  126.174 1.00 76.57  ? 325 ARG B NE    1 
ATOM   5705 C  CZ    . ARG C 1 325 ? 108.952 94.003  126.378 1.00 76.66  ? 325 ARG B CZ    1 
ATOM   5706 N  NH1   . ARG C 1 325 ? 108.190 94.755  125.601 1.00 74.55  ? 325 ARG B NH1   1 
ATOM   5707 N  NH2   . ARG C 1 325 ? 108.397 93.339  127.388 1.00 77.17  ? 325 ARG B NH2   1 
ATOM   5708 N  N     . PHE C 1 326 ? 109.974 95.467  120.502 1.00 64.80  ? 326 PHE B N     1 
ATOM   5709 C  CA    . PHE C 1 326 ? 108.629 95.816  120.059 1.00 63.72  ? 326 PHE B CA    1 
ATOM   5710 C  C     . PHE C 1 326 ? 108.225 95.003  118.838 1.00 70.45  ? 326 PHE B C     1 
ATOM   5711 O  O     . PHE C 1 326 ? 107.082 94.542  118.742 1.00 77.04  ? 326 PHE B O     1 
ATOM   5712 C  CB    . PHE C 1 326 ? 108.536 97.310  119.761 1.00 69.56  ? 326 PHE B CB    1 
ATOM   5713 C  CG    . PHE C 1 326 ? 107.132 97.793  119.543 1.00 68.60  ? 326 PHE B CG    1 
ATOM   5714 C  CD1   . PHE C 1 326 ? 106.154 97.563  120.493 1.00 67.28  ? 326 PHE B CD1   1 
ATOM   5715 C  CD2   . PHE C 1 326 ? 106.788 98.472  118.389 1.00 69.14  ? 326 PHE B CD2   1 
ATOM   5716 C  CE1   . PHE C 1 326 ? 104.862 98.004  120.297 1.00 71.00  ? 326 PHE B CE1   1 
ATOM   5717 C  CE2   . PHE C 1 326 ? 105.497 98.914  118.189 1.00 67.50  ? 326 PHE B CE2   1 
ATOM   5718 C  CZ    . PHE C 1 326 ? 104.534 98.681  119.143 1.00 70.09  ? 326 PHE B CZ    1 
ATOM   5719 N  N     . PHE C 1 327 ? 109.149 94.816  117.892 1.00 71.74  ? 327 PHE B N     1 
ATOM   5720 C  CA    . PHE C 1 327 ? 108.844 93.997  116.723 1.00 73.68  ? 327 PHE B CA    1 
ATOM   5721 C  C     . PHE C 1 327 ? 108.554 92.556  117.121 1.00 79.66  ? 327 PHE B C     1 
ATOM   5722 O  O     . PHE C 1 327 ? 107.612 91.940  116.608 1.00 85.18  ? 327 PHE B O     1 
ATOM   5723 C  CB    . PHE C 1 327 ? 109.996 94.056  115.722 1.00 73.74  ? 327 PHE B CB    1 
ATOM   5724 C  CG    . PHE C 1 327 ? 110.038 95.322  114.920 1.00 74.11  ? 327 PHE B CG    1 
ATOM   5725 C  CD1   . PHE C 1 327 ? 108.868 95.953  114.539 1.00 75.94  ? 327 PHE B CD1   1 
ATOM   5726 C  CD2   . PHE C 1 327 ? 111.246 95.881  114.546 1.00 74.16  ? 327 PHE B CD2   1 
ATOM   5727 C  CE1   . PHE C 1 327 ? 108.903 97.117  113.802 1.00 78.04  ? 327 PHE B CE1   1 
ATOM   5728 C  CE2   . PHE C 1 327 ? 111.286 97.044  113.809 1.00 76.69  ? 327 PHE B CE2   1 
ATOM   5729 C  CZ    . PHE C 1 327 ? 110.113 97.663  113.437 1.00 75.00  ? 327 PHE B CZ    1 
ATOM   5730 N  N     . ALA C 1 328 ? 109.350 92.004  118.041 1.00 80.45  ? 328 ALA B N     1 
ATOM   5731 C  CA    . ALA C 1 328 ? 109.110 90.639  118.499 1.00 82.53  ? 328 ALA B CA    1 
ATOM   5732 C  C     . ALA C 1 328 ? 107.756 90.515  119.186 1.00 83.78  ? 328 ALA B C     1 
ATOM   5733 O  O     . ALA C 1 328 ? 107.018 89.551  118.949 1.00 89.32  ? 328 ALA B O     1 
ATOM   5734 C  CB    . ALA C 1 328 ? 110.230 90.195  119.438 1.00 81.97  ? 328 ALA B CB    1 
ATOM   5735 N  N     . PHE C 1 329 ? 107.411 91.482  120.038 1.00 79.95  ? 329 PHE B N     1 
ATOM   5736 C  CA    . PHE C 1 329 ? 106.126 91.437  120.728 1.00 83.41  ? 329 PHE B CA    1 
ATOM   5737 C  C     . PHE C 1 329 ? 104.965 91.553  119.749 1.00 85.63  ? 329 PHE B C     1 
ATOM   5738 O  O     . PHE C 1 329 ? 103.950 90.860  119.893 1.00 96.65  ? 329 PHE B O     1 
ATOM   5739 C  CB    . PHE C 1 329 ? 106.050 92.547  121.776 1.00 81.87  ? 329 PHE B CB    1 
ATOM   5740 C  CG    . PHE C 1 329 ? 104.647 92.970  122.107 1.00 80.83  ? 329 PHE B CG    1 
ATOM   5741 C  CD1   . PHE C 1 329 ? 103.843 92.180  122.910 1.00 83.52  ? 329 PHE B CD1   1 
ATOM   5742 C  CD2   . PHE C 1 329 ? 104.131 94.156  121.613 1.00 79.84  ? 329 PHE B CD2   1 
ATOM   5743 C  CE1   . PHE C 1 329 ? 102.552 92.564  123.214 1.00 85.47  ? 329 PHE B CE1   1 
ATOM   5744 C  CE2   . PHE C 1 329 ? 102.841 94.544  121.914 1.00 79.07  ? 329 PHE B CE2   1 
ATOM   5745 C  CZ    . PHE C 1 329 ? 102.051 93.748  122.715 1.00 84.44  ? 329 PHE B CZ    1 
ATOM   5746 N  N     . LEU C 1 330 ? 105.086 92.439  118.757 1.00 79.41  ? 330 LEU B N     1 
ATOM   5747 C  CA    . LEU C 1 330 ? 104.032 92.573  117.758 1.00 81.28  ? 330 LEU B CA    1 
ATOM   5748 C  C     . LEU C 1 330 ? 103.870 91.287  116.961 1.00 91.01  ? 330 LEU B C     1 
ATOM   5749 O  O     . LEU C 1 330 ? 102.746 90.847  116.702 1.00 96.11  ? 330 LEU B O     1 
ATOM   5750 C  CB    . LEU C 1 330 ? 104.336 93.748  116.831 1.00 80.80  ? 330 LEU B CB    1 
ATOM   5751 C  CG    . LEU C 1 330 ? 103.775 95.104  117.261 1.00 78.99  ? 330 LEU B CG    1 
ATOM   5752 C  CD1   . LEU C 1 330 ? 104.029 96.155  116.198 1.00 81.59  ? 330 LEU B CD1   1 
ATOM   5753 C  CD2   . LEU C 1 330 ? 102.290 95.001  117.559 1.00 72.53  ? 330 LEU B CD2   1 
ATOM   5754 N  N     . ASN C 1 331 ? 104.984 90.665  116.574 1.00 92.01  ? 331 ASN B N     1 
ATOM   5755 C  CA    . ASN C 1 331 ? 104.909 89.403  115.849 1.00 92.41  ? 331 ASN B CA    1 
ATOM   5756 C  C     . ASN C 1 331 ? 104.231 88.346  116.715 1.00 95.53  ? 331 ASN B C     1 
ATOM   5757 O  O     . ASN C 1 331 ? 103.375 87.593  116.236 1.00 99.23  ? 331 ASN B O     1 
ATOM   5758 C  CB    . ASN C 1 331 ? 106.329 89.000  115.422 1.00 89.60  ? 331 ASN B CB    1 
ATOM   5759 C  CG    . ASN C 1 331 ? 106.507 87.506  115.123 1.00 99.18  ? 331 ASN B CG    1 
ATOM   5760 O  OD1   . ASN C 1 331 ? 105.573 86.708  115.125 1.00 104.46 ? 331 ASN B OD1   1 
ATOM   5761 N  ND2   . ASN C 1 331 ? 107.753 87.131  114.867 1.00 101.62 ? 331 ASN B ND2   1 
ATOM   5762 N  N     . GLU C 1 332 ? 104.570 88.305  118.004 1.00 93.83  ? 332 GLU B N     1 
ATOM   5763 C  CA    . GLU C 1 332 ? 103.995 87.303  118.894 1.00 97.55  ? 332 GLU B CA    1 
ATOM   5764 C  C     . GLU C 1 332 ? 102.495 87.509  119.089 1.00 100.82 ? 332 GLU B C     1 
ATOM   5765 O  O     . GLU C 1 332 ? 101.732 86.537  119.119 1.00 106.49 ? 332 GLU B O     1 
ATOM   5766 C  CB    . GLU C 1 332 ? 104.724 87.326  120.237 1.00 95.58  ? 332 GLU B CB    1 
ATOM   5767 C  CG    . GLU C 1 332 ? 103.833 87.125  121.448 1.00 102.87 ? 332 GLU B CG    1 
ATOM   5768 C  CD    . GLU C 1 332 ? 104.612 87.134  122.746 1.00 115.44 ? 332 GLU B CD    1 
ATOM   5769 O  OE1   . GLU C 1 332 ? 105.409 86.197  122.958 1.00 125.17 ? 332 GLU B OE1   1 
ATOM   5770 O  OE2   . GLU C 1 332 ? 104.430 88.071  123.552 1.00 113.63 ? 332 GLU B OE2   1 
ATOM   5771 N  N     . ARG C 1 333 ? 102.049 88.760  119.214 1.00 97.38  ? 333 ARG B N     1 
ATOM   5772 C  CA    . ARG C 1 333 ? 100.661 88.999  119.596 1.00 98.24  ? 333 ARG B CA    1 
ATOM   5773 C  C     . ARG C 1 333 ? 99.720  89.131  118.400 1.00 103.10 ? 333 ARG B C     1 
ATOM   5774 O  O     . ARG C 1 333 ? 98.610  88.590  118.438 1.00 112.11 ? 333 ARG B O     1 
ATOM   5775 C  CB    . ARG C 1 333 ? 100.567 90.241  120.491 1.00 96.13  ? 333 ARG B CB    1 
ATOM   5776 C  CG    . ARG C 1 333 ? 99.324  91.113  120.302 1.00 100.15 ? 333 ARG B CG    1 
ATOM   5777 C  CD    . ARG C 1 333 ? 98.050  90.444  120.828 1.00 109.49 ? 333 ARG B CD    1 
ATOM   5778 N  NE    . ARG C 1 333 ? 98.086  90.140  122.253 1.00 115.34 ? 333 ARG B NE    1 
ATOM   5779 C  CZ    . ARG C 1 333 ? 97.666  90.958  123.207 1.00 110.96 ? 333 ARG B CZ    1 
ATOM   5780 N  NH1   . ARG C 1 333 ? 97.186  92.158  122.927 1.00 103.91 ? 333 ARG B NH1   1 
ATOM   5781 N  NH2   . ARG C 1 333 ? 97.716  90.556  124.473 1.00 111.41 ? 333 ARG B NH2   1 
ATOM   5782 N  N     . MET C 1 334 ? 100.129 89.818  117.330 1.00 98.86  ? 334 MET B N     1 
ATOM   5783 C  CA    . MET C 1 334 ? 99.216  90.076  116.221 1.00 105.63 ? 334 MET B CA    1 
ATOM   5784 C  C     . MET C 1 334 ? 98.721  88.795  115.564 1.00 113.49 ? 334 MET B C     1 
ATOM   5785 O  O     . MET C 1 334 ? 97.722  88.832  114.838 1.00 115.99 ? 334 MET B O     1 
ATOM   5786 C  CB    . MET C 1 334 ? 99.895  90.966  115.180 1.00 103.00 ? 334 MET B CB    1 
ATOM   5787 C  CG    . MET C 1 334 ? 99.686  92.452  115.409 1.00 103.47 ? 334 MET B CG    1 
ATOM   5788 S  SD    . MET C 1 334 ? 98.086  92.816  116.150 1.00 109.30 ? 334 MET B SD    1 
ATOM   5789 C  CE    . MET C 1 334 ? 98.465  94.321  117.040 1.00 99.20  ? 334 MET B CE    1 
ATOM   5790 N  N     . GLU C 1 335 ? 99.397  87.668  115.798 1.00 112.98 ? 335 GLU B N     1 
ATOM   5791 C  CA    . GLU C 1 335 ? 98.910  86.391  115.290 1.00 114.13 ? 335 GLU B CA    1 
ATOM   5792 C  C     . GLU C 1 335 ? 97.551  86.036  115.881 1.00 113.32 ? 335 GLU B C     1 
ATOM   5793 O  O     . GLU C 1 335 ? 96.754  85.345  115.235 1.00 114.36 ? 335 GLU B O     1 
ATOM   5794 C  CB    . GLU C 1 335 ? 99.937  85.296  115.588 1.00 116.76 ? 335 GLU B CB    1 
ATOM   5795 C  CG    . GLU C 1 335 ? 99.470  83.881  115.297 1.00 123.79 ? 335 GLU B CG    1 
ATOM   5796 C  CD    . GLU C 1 335 ? 100.591 82.989  114.799 1.00 126.00 ? 335 GLU B CD    1 
ATOM   5797 O  OE1   . GLU C 1 335 ? 101.662 82.961  115.442 1.00 121.29 ? 335 GLU B OE1   1 
ATOM   5798 O  OE2   . GLU C 1 335 ? 100.404 82.323  113.760 1.00 129.62 ? 335 GLU B OE2   1 
ATOM   5799 N  N     . LYS C 1 336 ? 97.261  86.509  117.097 1.00 115.33 ? 336 LYS B N     1 
ATOM   5800 C  CA    . LYS C 1 336 ? 95.977  86.209  117.724 1.00 118.73 ? 336 LYS B CA    1 
ATOM   5801 C  C     . LYS C 1 336 ? 94.815  86.791  116.927 1.00 118.92 ? 336 LYS B C     1 
ATOM   5802 O  O     . LYS C 1 336 ? 93.789  86.128  116.739 1.00 121.07 ? 336 LYS B O     1 
ATOM   5803 C  CB    . LYS C 1 336 ? 95.947  86.742  119.157 1.00 30.00  ? 336 LYS B CB    1 
ATOM   5804 C  CG    . LYS C 1 336 ? 96.908  86.039  120.102 1.00 30.00  ? 336 LYS B CG    1 
ATOM   5805 C  CD    . LYS C 1 336 ? 96.844  86.633  121.499 1.00 30.00  ? 336 LYS B CD    1 
ATOM   5806 C  CE    . LYS C 1 336 ? 97.788  85.915  122.450 1.00 30.00  ? 336 LYS B CE    1 
ATOM   5807 N  NZ    . LYS C 1 336 ? 97.753  86.503  123.817 1.00 30.00  ? 336 LYS B NZ    1 
ATOM   5808 N  N     . VAL C 1 337 ? 94.955  88.031  116.452 1.00 117.40 ? 337 VAL B N     1 
ATOM   5809 C  CA    . VAL C 1 337 ? 93.879  88.641  115.678 1.00 120.07 ? 337 VAL B CA    1 
ATOM   5810 C  C     . VAL C 1 337 ? 93.808  88.003  114.293 1.00 125.74 ? 337 VAL B C     1 
ATOM   5811 O  O     . VAL C 1 337 ? 94.778  87.429  113.783 1.00 125.55 ? 337 VAL B O     1 
ATOM   5812 C  CB    . VAL C 1 337 ? 94.064  90.165  115.587 1.00 114.50 ? 337 VAL B CB    1 
ATOM   5813 C  CG1   . VAL C 1 337 ? 94.977  90.530  114.431 1.00 111.99 ? 337 VAL B CG1   1 
ATOM   5814 C  CG2   . VAL C 1 337 ? 92.717  90.859  115.452 1.00 110.92 ? 337 VAL B CG2   1 
ATOM   5815 N  N     . ASN C 1 338 ? 92.631  88.098  113.682 1.00 128.36 ? 338 ASN B N     1 
ATOM   5816 C  CA    . ASN C 1 338 ? 92.357  87.476  112.393 1.00 129.09 ? 338 ASN B CA    1 
ATOM   5817 C  C     . ASN C 1 338 ? 92.335  88.538  111.304 1.00 131.95 ? 338 ASN B C     1 
ATOM   5818 O  O     . ASN C 1 338 ? 91.709  89.591  111.468 1.00 129.52 ? 338 ASN B O     1 
ATOM   5819 C  CB    . ASN C 1 338 ? 91.027  86.721  112.421 1.00 129.39 ? 338 ASN B CB    1 
ATOM   5820 C  CG    . ASN C 1 338 ? 90.903  85.719  111.290 1.00 132.38 ? 338 ASN B CG    1 
ATOM   5821 O  OD1   . ASN C 1 338 ? 91.772  85.634  110.422 1.00 133.82 ? 338 ASN B OD1   1 
ATOM   5822 N  ND2   . ASN C 1 338 ? 89.817  84.955  111.293 1.00 129.67 ? 338 ASN B ND2   1 
ATOM   5823 N  N     . GLY C 1 339 ? 93.016  88.259  110.198 1.00 132.23 ? 339 GLY B N     1 
ATOM   5824 C  CA    . GLY C 1 339 ? 93.054  89.173  109.073 1.00 125.86 ? 339 GLY B CA    1 
ATOM   5825 C  C     . GLY C 1 339 ? 93.391  88.488  107.763 1.00 122.60 ? 339 GLY B C     1 
ATOM   5826 O  O     . GLY C 1 339 ? 93.617  87.279  107.725 1.00 121.27 ? 339 GLY B O     1 
ATOM   5827 O  "O5'" . DC  D 2 48  ? 79.059  139.482 123.339 1.00 196.79 ? 1   DC  D "O5'" 1 
ATOM   5828 C  "C5'" . DC  D 2 48  ? 80.471  139.311 123.370 1.00 198.71 ? 1   DC  D "C5'" 1 
ATOM   5829 C  "C4'" . DC  D 2 48  ? 80.935  138.925 124.762 1.00 199.70 ? 1   DC  D "C4'" 1 
ATOM   5830 O  "O4'" . DC  D 2 48  ? 80.651  140.006 125.680 1.00 201.78 ? 1   DC  D "O4'" 1 
ATOM   5831 C  "C3'" . DC  D 2 48  ? 80.241  137.711 125.352 1.00 201.36 ? 1   DC  D "C3'" 1 
ATOM   5832 O  "O3'" . DC  D 2 48  ? 80.921  136.527 124.957 1.00 203.28 ? 1   DC  D "O3'" 1 
ATOM   5833 C  "C2'" . DC  D 2 48  ? 80.374  137.959 126.851 1.00 198.66 ? 1   DC  D "C2'" 1 
ATOM   5834 C  "C1'" . DC  D 2 48  ? 80.262  139.484 126.940 1.00 200.67 ? 1   DC  D "C1'" 1 
ATOM   5835 N  N1    . DC  D 2 48  ? 78.881  139.970 127.257 1.00 200.96 ? 1   DC  D N1    1 
ATOM   5836 C  C2    . DC  D 2 48  ? 78.596  141.341 127.210 1.00 198.62 ? 1   DC  D C2    1 
ATOM   5837 O  O2    . DC  D 2 48  ? 79.492  142.136 126.902 1.00 196.22 ? 1   DC  D O2    1 
ATOM   5838 N  N3    . DC  D 2 48  ? 77.340  141.760 127.504 1.00 197.59 ? 1   DC  D N3    1 
ATOM   5839 C  C4    . DC  D 2 48  ? 76.399  140.874 127.833 1.00 197.73 ? 1   DC  D C4    1 
ATOM   5840 N  N4    . DC  D 2 48  ? 75.177  141.335 128.115 1.00 191.75 ? 1   DC  D N4    1 
ATOM   5841 C  C5    . DC  D 2 48  ? 76.670  139.475 127.889 1.00 199.46 ? 1   DC  D C5    1 
ATOM   5842 C  C6    . DC  D 2 48  ? 77.911  139.072 127.598 1.00 199.29 ? 1   DC  D C6    1 
ATOM   5843 P  P     . DC  D 2 49  ? 80.095  135.263 124.408 1.00 208.91 ? 2   DC  D P     1 
ATOM   5844 O  OP1   . DC  D 2 49  ? 79.000  135.782 123.560 1.00 205.60 ? 2   DC  D OP1   1 
ATOM   5845 O  OP2   . DC  D 2 49  ? 79.795  134.388 125.563 1.00 203.81 ? 2   DC  D OP2   1 
ATOM   5846 O  "O5'" . DC  D 2 49  ? 81.138  134.496 123.467 1.00 202.35 ? 2   DC  D "O5'" 1 
ATOM   5847 C  "C5'" . DC  D 2 49  ? 81.315  134.910 122.114 1.00 197.59 ? 2   DC  D "C5'" 1 
ATOM   5848 C  "C4'" . DC  D 2 49  ? 82.652  135.610 121.927 1.00 197.57 ? 2   DC  D "C4'" 1 
ATOM   5849 O  "O4'" . DC  D 2 49  ? 82.990  136.332 123.140 1.00 199.00 ? 2   DC  D "O4'" 1 
ATOM   5850 C  "C3'" . DC  D 2 49  ? 83.840  134.686 121.676 1.00 195.35 ? 2   DC  D "C3'" 1 
ATOM   5851 O  "O3'" . DC  D 2 49  ? 84.849  135.396 120.963 1.00 194.67 ? 2   DC  D "O3'" 1 
ATOM   5852 C  "C2'" . DC  D 2 49  ? 84.294  134.394 123.095 1.00 193.28 ? 2   DC  D "C2'" 1 
ATOM   5853 C  "C1'" . DC  D 2 49  ? 84.174  135.786 123.687 1.00 195.48 ? 2   DC  D "C1'" 1 
ATOM   5854 N  N1    . DC  D 2 49  ? 84.075  135.820 125.162 1.00 195.10 ? 2   DC  D N1    1 
ATOM   5855 C  C2    . DC  D 2 49  ? 84.591  136.917 125.842 1.00 191.59 ? 2   DC  D C2    1 
ATOM   5856 O  O2    . DC  D 2 49  ? 85.124  137.825 125.195 1.00 189.13 ? 2   DC  D O2    1 
ATOM   5857 N  N3    . DC  D 2 49  ? 84.503  136.956 127.191 1.00 191.97 ? 2   DC  D N3    1 
ATOM   5858 C  C4    . DC  D 2 49  ? 83.925  135.955 127.852 1.00 191.09 ? 2   DC  D C4    1 
ATOM   5859 N  N4    . DC  D 2 49  ? 83.864  136.049 129.185 1.00 188.19 ? 2   DC  D N4    1 
ATOM   5860 C  C5    . DC  D 2 49  ? 83.385  134.821 127.175 1.00 192.92 ? 2   DC  D C5    1 
ATOM   5861 C  C6    . DC  D 2 49  ? 83.481  134.795 125.840 1.00 195.35 ? 2   DC  D C6    1 
ATOM   5862 P  P     . DA  D 2 50  ? 85.668  134.690 119.775 1.00 192.52 ? 3   DA  D P     1 
ATOM   5863 O  OP1   . DA  D 2 50  ? 84.932  134.954 118.519 1.00 189.56 ? 3   DA  D OP1   1 
ATOM   5864 O  OP2   . DA  D 2 50  ? 85.961  133.297 120.180 1.00 191.11 ? 3   DA  D OP2   1 
ATOM   5865 O  "O5'" . DA  D 2 50  ? 87.055  135.489 119.732 1.00 190.03 ? 3   DA  D "O5'" 1 
ATOM   5866 C  "C5'" . DA  D 2 50  ? 88.142  135.088 120.568 1.00 189.25 ? 3   DA  D "C5'" 1 
ATOM   5867 C  "C4'" . DA  D 2 50  ? 88.383  136.095 121.680 1.00 187.77 ? 3   DA  D "C4'" 1 
ATOM   5868 O  "O4'" . DA  D 2 50  ? 87.534  135.785 122.796 1.00 187.95 ? 3   DA  D "O4'" 1 
ATOM   5869 C  "C3'" . DA  D 2 50  ? 89.805  136.097 122.239 1.00 182.79 ? 3   DA  D "C3'" 1 
ATOM   5870 O  "O3'" . DA  D 2 50  ? 90.535  137.193 121.707 1.00 185.47 ? 3   DA  D "O3'" 1 
ATOM   5871 C  "C2'" . DA  D 2 50  ? 89.631  136.224 123.764 1.00 180.22 ? 3   DA  D "C2'" 1 
ATOM   5872 C  "C1'" . DA  D 2 50  ? 88.118  136.301 123.962 1.00 184.30 ? 3   DA  D "C1'" 1 
ATOM   5873 N  N9    . DA  D 2 50  ? 87.640  135.523 125.100 1.00 184.59 ? 3   DA  D N9    1 
ATOM   5874 C  C8    . DA  D 2 50  ? 87.036  134.297 125.065 1.00 183.87 ? 3   DA  D C8    1 
ATOM   5875 N  N7    . DA  D 2 50  ? 86.706  133.835 126.248 1.00 182.26 ? 3   DA  D N7    1 
ATOM   5876 C  C5    . DA  D 2 50  ? 87.126  134.825 127.119 1.00 183.97 ? 3   DA  D C5    1 
ATOM   5877 C  C6    . DA  D 2 50  ? 87.065  134.943 128.521 1.00 181.96 ? 3   DA  D C6    1 
ATOM   5878 N  N6    . DA  D 2 50  ? 86.537  134.008 129.317 1.00 179.53 ? 3   DA  D N6    1 
ATOM   5879 N  N1    . DA  D 2 50  ? 87.576  136.061 129.076 1.00 180.51 ? 3   DA  D N1    1 
ATOM   5880 C  C2    . DA  D 2 50  ? 88.107  136.993 128.277 1.00 180.97 ? 3   DA  D C2    1 
ATOM   5881 N  N3    . DA  D 2 50  ? 88.217  136.996 126.950 1.00 182.21 ? 3   DA  D N3    1 
ATOM   5882 C  C4    . DA  D 2 50  ? 87.703  135.872 126.428 1.00 183.96 ? 3   DA  D C4    1 
ATOM   5883 P  P     . DC  D 2 51  ? 91.435  136.997 120.392 1.00 190.78 ? 4   DC  D P     1 
ATOM   5884 O  OP1   . DC  D 2 51  ? 90.686  137.574 119.254 1.00 190.28 ? 4   DC  D OP1   1 
ATOM   5885 O  OP2   . DC  D 2 51  ? 91.861  135.581 120.349 1.00 182.19 ? 4   DC  D OP2   1 
ATOM   5886 O  "O5'" . DC  D 2 51  ? 92.729  137.897 120.668 1.00 188.04 ? 4   DC  D "O5'" 1 
ATOM   5887 C  "C5'" . DC  D 2 51  ? 93.906  137.309 121.213 1.00 184.68 ? 4   DC  D "C5'" 1 
ATOM   5888 C  "C4'" . DC  D 2 51  ? 94.172  137.825 122.615 1.00 181.38 ? 4   DC  D "C4'" 1 
ATOM   5889 O  "O4'" . DC  D 2 51  ? 93.194  137.263 123.531 1.00 180.70 ? 4   DC  D "O4'" 1 
ATOM   5890 C  "C3'" . DC  D 2 51  ? 95.531  137.445 123.191 1.00 179.15 ? 4   DC  D "C3'" 1 
ATOM   5891 O  "O3'" . DC  D 2 51  ? 95.963  138.446 124.109 1.00 180.82 ? 4   DC  D "O3'" 1 
ATOM   5892 C  "C2'" . DC  D 2 51  ? 95.214  136.138 123.903 1.00 175.90 ? 4   DC  D "C2'" 1 
ATOM   5893 C  "C1'" . DC  D 2 51  ? 93.851  136.461 124.493 1.00 176.70 ? 4   DC  D "C1'" 1 
ATOM   5894 N  N1    . DC  D 2 51  ? 93.017  135.259 124.759 1.00 174.19 ? 4   DC  D N1    1 
ATOM   5895 C  C2    . DC  D 2 51  ? 92.130  135.259 125.840 1.00 172.38 ? 4   DC  D C2    1 
ATOM   5896 O  O2    . DC  D 2 51  ? 92.050  136.266 126.554 1.00 174.27 ? 4   DC  D O2    1 
ATOM   5897 N  N3    . DC  D 2 51  ? 91.376  134.157 126.070 1.00 169.53 ? 4   DC  D N3    1 
ATOM   5898 C  C4    . DC  D 2 51  ? 91.491  133.093 125.275 1.00 167.22 ? 4   DC  D C4    1 
ATOM   5899 N  N4    . DC  D 2 51  ? 90.729  132.028 125.542 1.00 164.28 ? 4   DC  D N4    1 
ATOM   5900 C  C5    . DC  D 2 51  ? 92.393  133.073 124.170 1.00 167.27 ? 4   DC  D C5    1 
ATOM   5901 C  C6    . DC  D 2 51  ? 93.129  134.166 123.953 1.00 171.54 ? 4   DC  D C6    1 
ATOM   5902 P  P     . DG  D 2 52  ? 97.505  138.535 124.557 1.00 189.50 ? 5   DG  D P     1 
ATOM   5903 O  OP1   . DG  D 2 52  ? 98.019  139.856 124.135 1.00 188.34 ? 5   DG  D OP1   1 
ATOM   5904 O  OP2   . DG  D 2 52  ? 98.187  137.303 124.106 1.00 179.13 ? 5   DG  D OP2   1 
ATOM   5905 O  "O5'" . DG  D 2 52  ? 97.440  138.496 126.153 1.00 177.17 ? 5   DG  D "O5'" 1 
ATOM   5906 C  "C5'" . DG  D 2 52  ? 96.693  137.476 126.803 1.00 166.34 ? 5   DG  D "C5'" 1 
ATOM   5907 C  "C4'" . DG  D 2 52  ? 96.931  137.495 128.298 1.00 153.26 ? 5   DG  D "C4'" 1 
ATOM   5908 O  "O4'" . DG  D 2 52  ? 96.076  136.511 128.928 1.00 145.66 ? 5   DG  D "O4'" 1 
ATOM   5909 C  "C3'" . DG  D 2 52  ? 98.318  137.086 128.728 1.00 148.26 ? 5   DG  D "C3'" 1 
ATOM   5910 O  "O3'" . DG  D 2 52  ? 98.491  137.454 130.082 1.00 149.94 ? 5   DG  D "O3'" 1 
ATOM   5911 C  "C2'" . DG  D 2 52  ? 98.214  135.575 128.585 1.00 144.32 ? 5   DG  D "C2'" 1 
ATOM   5912 C  "C1'" . DG  D 2 52  ? 96.829  135.332 129.185 1.00 144.22 ? 5   DG  D "C1'" 1 
ATOM   5913 N  N9    . DG  D 2 52  ? 96.107  134.212 128.598 1.00 144.37 ? 5   DG  D N9    1 
ATOM   5914 C  C8    . DG  D 2 52  ? 96.421  133.522 127.453 1.00 145.01 ? 5   DG  D C8    1 
ATOM   5915 N  N7    . DG  D 2 52  ? 95.562  132.580 127.166 1.00 146.94 ? 5   DG  D N7    1 
ATOM   5916 C  C5    . DG  D 2 52  ? 94.620  132.657 128.185 1.00 150.53 ? 5   DG  D C5    1 
ATOM   5917 C  C6    . DG  D 2 52  ? 93.451  131.888 128.415 1.00 151.71 ? 5   DG  D C6    1 
ATOM   5918 O  O6    . DG  D 2 52  ? 92.999  130.953 127.741 1.00 150.31 ? 5   DG  D O6    1 
ATOM   5919 N  N1    . DG  D 2 52  ? 92.785  132.300 129.566 1.00 154.07 ? 5   DG  D N1    1 
ATOM   5920 C  C2    . DG  D 2 52  ? 93.193  133.322 130.383 1.00 156.59 ? 5   DG  D C2    1 
ATOM   5921 N  N2    . DG  D 2 52  ? 92.426  133.563 131.451 1.00 158.70 ? 5   DG  D N2    1 
ATOM   5922 N  N3    . DG  D 2 52  ? 94.280  134.046 130.181 1.00 155.20 ? 5   DG  D N3    1 
ATOM   5923 C  C4    . DG  D 2 52  ? 94.941  133.661 129.067 1.00 151.19 ? 5   DG  D C4    1 
ATOM   5924 P  P     . DC  D 2 53  ? 99.953  137.676 130.704 1.00 152.24 ? 6   DC  D P     1 
ATOM   5925 O  OP1   . DC  D 2 53  ? 100.255 139.122 130.626 1.00 146.77 ? 6   DC  D OP1   1 
ATOM   5926 O  OP2   . DC  D 2 53  ? 100.872 136.693 130.088 1.00 149.31 ? 6   DC  D OP2   1 
ATOM   5927 O  "O5'" . DC  D 2 53  ? 99.756  137.276 132.237 1.00 143.00 ? 6   DC  D "O5'" 1 
ATOM   5928 C  "C5'" . DC  D 2 53  ? 98.607  137.735 132.939 1.00 133.47 ? 6   DC  D "C5'" 1 
ATOM   5929 C  "C4'" . DC  D 2 53  ? 97.901  136.587 133.640 1.00 127.18 ? 6   DC  D "C4'" 1 
ATOM   5930 O  "O4'" . DC  D 2 53  ? 97.422  135.630 132.660 1.00 127.90 ? 6   DC  D "O4'" 1 
ATOM   5931 C  "C3'" . DC  D 2 53  ? 98.768  135.796 134.623 1.00 127.74 ? 6   DC  D "C3'" 1 
ATOM   5932 O  "O3'" . DC  D 2 53  ? 98.083  135.642 135.854 1.00 129.95 ? 6   DC  D "O3'" 1 
ATOM   5933 C  "C2'" . DC  D 2 53  ? 98.968  134.451 133.924 1.00 126.73 ? 6   DC  D "C2'" 1 
ATOM   5934 C  "C1'" . DC  D 2 53  ? 97.684  134.332 133.129 1.00 126.81 ? 6   DC  D "C1'" 1 
ATOM   5935 N  N1    . DC  D 2 53  ? 97.795  133.415 131.962 1.00 131.99 ? 6   DC  D N1    1 
ATOM   5936 C  C2    . DC  D 2 53  ? 96.722  132.584 131.629 1.00 131.23 ? 6   DC  D C2    1 
ATOM   5937 O  O2    . DC  D 2 53  ? 95.690  132.630 132.309 1.00 127.72 ? 6   DC  D O2    1 
ATOM   5938 N  N3    . DC  D 2 53  ? 96.843  131.752 130.566 1.00 132.87 ? 6   DC  D N3    1 
ATOM   5939 C  C4    . DC  D 2 53  ? 97.971  131.734 129.857 1.00 130.82 ? 6   DC  D C4    1 
ATOM   5940 N  N4    . DC  D 2 53  ? 98.044  130.899 128.817 1.00 128.63 ? 6   DC  D N4    1 
ATOM   5941 C  C5    . DC  D 2 53  ? 99.077  132.571 130.185 1.00 132.43 ? 6   DC  D C5    1 
ATOM   5942 C  C6    . DC  D 2 53  ? 98.947  133.385 131.236 1.00 133.16 ? 6   DC  D C6    1 
ATOM   5943 P  P     . DA  D 2 54  ? 98.895  135.287 137.193 1.00 122.98 ? 7   DA  D P     1 
ATOM   5944 O  OP1   . DA  D 2 54  ? 98.725  136.416 138.134 1.00 121.17 ? 7   DA  D OP1   1 
ATOM   5945 O  OP2   . DA  D 2 54  ? 100.253 134.857 136.798 1.00 106.93 ? 7   DA  D OP2   1 
ATOM   5946 O  "O5'" . DA  D 2 54  ? 98.132  134.008 137.769 1.00 119.28 ? 7   DA  D "O5'" 1 
ATOM   5947 C  "C5'" . DA  D 2 54  ? 96.718  134.022 137.904 1.00 118.54 ? 7   DA  D "C5'" 1 
ATOM   5948 C  "C4'" . DA  D 2 54  ? 96.182  132.611 138.045 1.00 112.78 ? 7   DA  D "C4'" 1 
ATOM   5949 O  "O4'" . DA  D 2 54  ? 96.150  131.971 136.743 1.00 107.19 ? 7   DA  D "O4'" 1 
ATOM   5950 C  "C3'" . DA  D 2 54  ? 97.010  131.703 138.951 1.00 111.40 ? 7   DA  D "C3'" 1 
ATOM   5951 O  "O3'" . DA  D 2 54  ? 96.160  130.940 139.785 1.00 117.65 ? 7   DA  D "O3'" 1 
ATOM   5952 C  "C2'" . DA  D 2 54  ? 97.776  130.822 137.968 1.00 105.23 ? 7   DA  D "C2'" 1 
ATOM   5953 C  "C1'" . DA  D 2 54  ? 96.805  130.725 136.803 1.00 103.80 ? 7   DA  D "C1'" 1 
ATOM   5954 N  N9    . DA  D 2 54  ? 97.463  130.491 135.519 1.00 109.21 ? 7   DA  D N9    1 
ATOM   5955 C  C8    . DA  D 2 54  ? 98.589  131.104 135.051 1.00 113.95 ? 7   DA  D C8    1 
ATOM   5956 N  N7    . DA  D 2 54  ? 98.957  130.698 133.859 1.00 113.04 ? 7   DA  D N7    1 
ATOM   5957 C  C5    . DA  D 2 54  ? 98.006  129.754 133.520 1.00 114.52 ? 7   DA  D C5    1 
ATOM   5958 C  C6    . DA  D 2 54  ? 97.833  128.952 132.375 1.00 117.70 ? 7   DA  D C6    1 
ATOM   5959 N  N6    . DA  D 2 54  ? 98.656  128.984 131.323 1.00 118.94 ? 7   DA  D N6    1 
ATOM   5960 N  N1    . DA  D 2 54  ? 96.779  128.112 132.354 1.00 118.26 ? 7   DA  D N1    1 
ATOM   5961 C  C2    . DA  D 2 54  ? 95.959  128.081 133.411 1.00 116.13 ? 7   DA  D C2    1 
ATOM   5962 N  N3    . DA  D 2 54  ? 96.017  128.788 134.540 1.00 111.25 ? 7   DA  D N3    1 
ATOM   5963 C  C4    . DA  D 2 54  ? 97.075  129.613 134.531 1.00 111.93 ? 7   DA  D C4    1 
ATOM   5964 P  P     . DT  D 2 55  ? 96.708  130.360 141.179 1.00 124.23 ? 8   DT  D P     1 
ATOM   5965 O  OP1   . DT  D 2 55  ? 96.021  131.083 142.270 1.00 122.73 ? 8   DT  D OP1   1 
ATOM   5966 O  OP2   . DT  D 2 55  ? 98.187  130.350 141.115 1.00 109.54 ? 8   DT  D OP2   1 
ATOM   5967 O  "O5'" . DT  D 2 55  ? 96.223  128.841 141.170 1.00 121.56 ? 8   DT  D "O5'" 1 
ATOM   5968 C  "C5'" . DT  D 2 55  ? 94.906  128.525 140.750 1.00 113.32 ? 8   DT  D "C5'" 1 
ATOM   5969 C  "C4'" . DT  D 2 55  ? 94.865  127.158 140.094 1.00 110.40 ? 8   DT  D "C4'" 1 
ATOM   5970 O  "O4'" . DT  D 2 55  ? 95.527  127.213 138.805 1.00 104.91 ? 8   DT  D "O4'" 1 
ATOM   5971 C  "C3'" . DT  D 2 55  ? 95.558  126.040 140.883 1.00 106.09 ? 8   DT  D "C3'" 1 
ATOM   5972 O  "O3'" . DT  D 2 55  ? 94.688  124.926 141.009 1.00 107.05 ? 8   DT  D "O3'" 1 
ATOM   5973 C  "C2'" . DT  D 2 55  ? 96.786  125.705 140.032 1.00 93.18  ? 8   DT  D "C2'" 1 
ATOM   5974 C  "C1'" . DT  D 2 55  ? 96.290  126.048 138.642 1.00 93.76  ? 8   DT  D "C1'" 1 
ATOM   5975 N  N1    . DT  D 2 55  ? 97.381  126.319 137.667 1.00 95.09  ? 8   DT  D N1    1 
ATOM   5976 C  C2    . DT  D 2 55  ? 97.390  125.646 136.472 1.00 93.15  ? 8   DT  D C2    1 
ATOM   5977 O  O2    . DT  D 2 55  ? 96.542  124.830 136.161 1.00 93.45  ? 8   DT  D O2    1 
ATOM   5978 N  N3    . DT  D 2 55  ? 98.431  125.962 135.644 1.00 90.71  ? 8   DT  D N3    1 
ATOM   5979 C  C4    . DT  D 2 55  ? 99.446  126.865 135.888 1.00 92.24  ? 8   DT  D C4    1 
ATOM   5980 O  O4    . DT  D 2 55  ? 100.340 127.080 135.078 1.00 91.11  ? 8   DT  D O4    1 
ATOM   5981 C  C5    . DT  D 2 55  ? 99.382  127.538 137.160 1.00 95.78  ? 8   DT  D C5    1 
ATOM   5982 C  C7    . DT  D 2 55  ? 100.433 128.540 137.535 1.00 88.78  ? 8   DT  D C7    1 
ATOM   5983 C  C6    . DT  D 2 55  ? 98.363  127.236 137.982 1.00 100.14 ? 8   DT  D C6    1 
ATOM   5984 P  P     . DC  D 2 56  ? 95.039  123.736 142.028 1.00 111.66 ? 9   DC  D P     1 
ATOM   5985 O  OP1   . DC  D 2 56  ? 93.851  123.502 142.877 1.00 109.23 ? 9   DC  D OP1   1 
ATOM   5986 O  OP2   . DC  D 2 56  ? 96.340  124.047 142.658 1.00 95.95  ? 9   DC  D OP2   1 
ATOM   5987 O  "O5'" . DC  D 2 56  ? 95.252  122.472 141.074 1.00 98.45  ? 9   DC  D "O5'" 1 
ATOM   5988 C  "C5'" . DC  D 2 56  ? 94.231  122.092 140.164 1.00 91.12  ? 9   DC  D "C5'" 1 
ATOM   5989 C  "C4'" . DC  D 2 56  ? 94.771  121.142 139.110 1.00 88.42  ? 9   DC  D "C4'" 1 
ATOM   5990 O  "O4'" . DC  D 2 56  ? 95.761  121.825 138.297 1.00 89.70  ? 9   DC  D "O4'" 1 
ATOM   5991 C  "C3'" . DC  D 2 56  ? 95.458  119.890 139.656 1.00 80.35  ? 9   DC  D "C3'" 1 
ATOM   5992 O  "O3'" . DC  D 2 56  ? 95.067  118.760 138.892 1.00 84.68  ? 9   DC  D "O3'" 1 
ATOM   5993 C  "C2'" . DC  D 2 56  ? 96.941  120.203 139.476 1.00 73.50  ? 9   DC  D "C2'" 1 
ATOM   5994 C  "C1'" . DC  D 2 56  ? 96.919  121.032 138.205 1.00 77.93  ? 9   DC  D "C1'" 1 
ATOM   5995 N  N1    . DC  D 2 56  ? 98.101  121.930 138.053 1.00 75.81  ? 9   DC  D N1    1 
ATOM   5996 C  C2    . DC  D 2 56  ? 98.860  121.880 136.881 1.00 72.58  ? 9   DC  D C2    1 
ATOM   5997 O  O2    . DC  D 2 56  ? 98.535  121.091 135.989 1.00 74.56  ? 9   DC  D O2    1 
ATOM   5998 N  N3    . DC  D 2 56  ? 99.930  122.701 136.755 1.00 70.26  ? 9   DC  D N3    1 
ATOM   5999 C  C4    . DC  D 2 56  ? 100.247 123.536 137.743 1.00 74.17  ? 9   DC  D C4    1 
ATOM   6000 N  N4    . DC  D 2 56  ? 101.310 124.326 137.575 1.00 73.34  ? 9   DC  D N4    1 
ATOM   6001 C  C5    . DC  D 2 56  ? 99.486  123.602 138.945 1.00 80.39  ? 9   DC  D C5    1 
ATOM   6002 C  C6    . DC  D 2 56  ? 98.433  122.788 139.057 1.00 79.52  ? 9   DC  D C6    1 
ATOM   6003 P  P     . DC  D 2 57  ? 95.300  117.273 139.451 1.00 89.43  ? 10  DC  D P     1 
ATOM   6004 O  OP1   . DC  D 2 57  ? 93.990  116.588 139.469 1.00 83.53  ? 10  DC  D OP1   1 
ATOM   6005 O  OP2   . DC  D 2 57  ? 96.100  117.357 140.689 1.00 80.13  ? 10  DC  D OP2   1 
ATOM   6006 O  "O5'" . DC  D 2 57  ? 96.210  116.592 138.331 1.00 78.01  ? 10  DC  D "O5'" 1 
ATOM   6007 C  "C5'" . DC  D 2 57  ? 95.803  116.628 136.970 1.00 75.97  ? 10  DC  D "C5'" 1 
ATOM   6008 C  "C4'" . DC  D 2 57  ? 96.915  116.127 136.071 1.00 68.01  ? 10  DC  D "C4'" 1 
ATOM   6009 O  "O4'" . DC  D 2 57  ? 97.891  117.181 135.876 1.00 67.52  ? 10  DC  D "O4'" 1 
ATOM   6010 C  "C3'" . DC  D 2 57  ? 97.677  114.927 136.620 1.00 65.75  ? 10  DC  D "C3'" 1 
ATOM   6011 O  "O3'" . DC  D 2 57  ? 97.883  113.965 135.603 1.00 70.19  ? 10  DC  D "O3'" 1 
ATOM   6012 C  "C2'" . DC  D 2 57  ? 98.993  115.524 137.110 1.00 63.67  ? 10  DC  D "C2'" 1 
ATOM   6013 C  "C1'" . DC  D 2 57  ? 99.182  116.711 136.183 1.00 60.16  ? 10  DC  D "C1'" 1 
ATOM   6014 N  N1    . DC  D 2 57  ? 99.938  117.826 136.809 1.00 57.42  ? 10  DC  D N1    1 
ATOM   6015 C  C2    . DC  D 2 57  ? 101.051 118.363 136.159 1.00 57.00  ? 10  DC  D C2    1 
ATOM   6016 O  O2    . DC  D 2 57  ? 101.393 117.895 135.070 1.00 60.59  ? 10  DC  D O2    1 
ATOM   6017 N  N3    . DC  D 2 57  ? 101.725 119.382 136.744 1.00 57.67  ? 10  DC  D N3    1 
ATOM   6018 C  C4    . DC  D 2 57  ? 101.321 119.855 137.921 1.00 62.57  ? 10  DC  D C4    1 
ATOM   6019 N  N4    . DC  D 2 57  ? 102.011 120.860 138.464 1.00 66.78  ? 10  DC  D N4    1 
ATOM   6020 C  C5    . DC  D 2 57  ? 100.191 119.321 138.597 1.00 64.52  ? 10  DC  D C5    1 
ATOM   6021 C  C6    . DC  D 2 57  ? 99.535  118.318 138.010 1.00 62.32  ? 10  DC  D C6    1 
ATOM   6022 P  P     . DA  D 2 58  ? 97.931  112.407 135.981 1.00 95.66  ? 11  DA  D P     1 
ATOM   6023 O  OP1   . DA  D 2 58  ? 97.126  111.672 134.983 1.00 90.96  ? 11  DA  D OP1   1 
ATOM   6024 O  OP2   . DA  D 2 58  ? 97.607  112.289 137.418 1.00 83.77  ? 11  DA  D OP2   1 
ATOM   6025 O  "O5'" . DA  D 2 58  ? 99.469  112.020 135.802 1.00 76.30  ? 11  DA  D "O5'" 1 
ATOM   6026 C  "C5'" . DA  D 2 58  ? 100.078 112.141 134.532 1.00 70.20  ? 11  DA  D "C5'" 1 
ATOM   6027 C  "C4'" . DA  D 2 58  ? 101.553 112.462 134.666 1.00 62.38  ? 11  DA  D "C4'" 1 
ATOM   6028 O  "O4'" . DA  D 2 58  ? 101.720 113.680 135.417 1.00 52.20  ? 11  DA  D "O4'" 1 
ATOM   6029 C  "C3'" . DA  D 2 58  ? 102.392 111.401 135.384 1.00 64.25  ? 11  DA  D "C3'" 1 
ATOM   6030 O  "O3'" . DA  D 2 58  ? 103.354 110.872 134.480 1.00 62.25  ? 11  DA  D "O3'" 1 
ATOM   6031 C  "C2'" . DA  D 2 58  ? 103.046 112.158 136.553 1.00 55.84  ? 11  DA  D "C2'" 1 
ATOM   6032 C  "C1'" . DA  D 2 58  ? 102.931 113.605 136.110 1.00 53.49  ? 11  DA  D "C1'" 1 
ATOM   6033 N  N9    . DA  D 2 58  ? 102.889 114.555 137.212 1.00 53.32  ? 11  DA  D N9    1 
ATOM   6034 C  C8    . DA  D 2 58  ? 101.988 114.588 138.233 1.00 54.05  ? 11  DA  D C8    1 
ATOM   6035 N  N7    . DA  D 2 58  ? 102.185 115.569 139.080 1.00 54.68  ? 11  DA  D N7    1 
ATOM   6036 C  C5    . DA  D 2 58  ? 103.292 116.224 138.576 1.00 51.58  ? 11  DA  D C5    1 
ATOM   6037 C  C6    . DA  D 2 58  ? 104.007 117.352 139.015 1.00 50.25  ? 11  DA  D C6    1 
ATOM   6038 N  N6    . DA  D 2 58  ? 103.689 118.040 140.114 1.00 53.48  ? 11  DA  D N6    1 
ATOM   6039 N  N1    . DA  D 2 58  ? 105.064 117.746 138.281 1.00 45.89  ? 11  DA  D N1    1 
ATOM   6040 C  C2    . DA  D 2 58  ? 105.379 117.055 137.181 1.00 44.74  ? 11  DA  D C2    1 
ATOM   6041 N  N3    . DA  D 2 58  ? 104.782 115.982 136.669 1.00 45.80  ? 11  DA  D N3    1 
ATOM   6042 C  C4    . DA  D 2 58  ? 103.734 115.616 137.421 1.00 50.66  ? 11  DA  D C4    1 
ATOM   6043 P  P     . DC  D 2 59  ? 104.601 110.010 135.009 1.00 61.46  ? 12  DC  D P     1 
ATOM   6044 O  OP1   . DC  D 2 59  ? 105.062 109.180 133.879 1.00 57.61  ? 12  DC  D OP1   1 
ATOM   6045 O  OP2   . DC  D 2 59  ? 104.232 109.359 136.284 1.00 60.01  ? 12  DC  D OP2   1 
ATOM   6046 O  "O5'" . DC  D 2 59  ? 105.731 111.107 135.273 1.00 58.52  ? 12  DC  D "O5'" 1 
ATOM   6047 C  "C5'" . DC  D 2 59  ? 106.293 111.827 134.181 1.00 53.36  ? 12  DC  D "C5'" 1 
ATOM   6048 C  "C4'" . DC  D 2 59  ? 107.654 112.366 134.558 1.00 39.37  ? 12  DC  D "C4'" 1 
ATOM   6049 O  "O4'" . DC  D 2 59  ? 107.489 113.616 135.246 1.00 30.69  ? 12  DC  D "O4'" 1 
ATOM   6050 C  "C3'" . DC  D 2 59  ? 108.422 111.471 135.506 1.00 45.74  ? 12  DC  D "C3'" 1 
ATOM   6051 O  "O3'" . DC  D 2 59  ? 109.287 110.625 134.764 1.00 43.71  ? 12  DC  D "O3'" 1 
ATOM   6052 C  "C2'" . DC  D 2 59  ? 109.212 112.440 136.384 1.00 42.11  ? 12  DC  D "C2'" 1 
ATOM   6053 C  "C1'" . DC  D 2 59  ? 108.478 113.768 136.236 1.00 32.13  ? 12  DC  D "C1'" 1 
ATOM   6054 N  N1    . DC  D 2 59  ? 107.811 114.234 137.471 1.00 35.87  ? 12  DC  D N1    1 
ATOM   6055 C  C2    . DC  D 2 59  ? 108.337 115.320 138.164 1.00 41.56  ? 12  DC  D C2    1 
ATOM   6056 O  O2    . DC  D 2 59  ? 109.369 115.848 137.743 1.00 42.55  ? 12  DC  D O2    1 
ATOM   6057 N  N3    . DC  D 2 59  ? 107.706 115.755 139.280 1.00 42.85  ? 12  DC  D N3    1 
ATOM   6058 C  C4    . DC  D 2 59  ? 106.595 115.148 139.693 1.00 41.76  ? 12  DC  D C4    1 
ATOM   6059 N  N4    . DC  D 2 59  ? 106.001 115.608 140.799 1.00 40.93  ? 12  DC  D N4    1 
ATOM   6060 C  C5    . DC  D 2 59  ? 106.042 114.041 138.994 1.00 43.20  ? 12  DC  D C5    1 
ATOM   6061 C  C6    . DC  D 2 59  ? 106.673 113.625 137.895 1.00 42.14  ? 12  DC  D C6    1 
ATOM   6062 P  P     . DC  D 2 60  ? 109.984 109.364 135.468 1.00 52.72  ? 13  DC  D P     1 
ATOM   6063 O  OP1   . DC  D 2 60  ? 110.490 108.485 134.395 1.00 54.47  ? 13  DC  D OP1   1 
ATOM   6064 O  OP2   . DC  D 2 60  ? 109.051 108.835 136.488 1.00 50.46  ? 13  DC  D OP2   1 
ATOM   6065 O  "O5'" . DC  D 2 60  ? 111.233 109.999 136.225 1.00 37.77  ? 13  DC  D "O5'" 1 
ATOM   6066 C  "C5'" . DC  D 2 60  ? 112.178 110.755 135.497 1.00 40.95  ? 13  DC  D "C5'" 1 
ATOM   6067 C  "C4'" . DC  D 2 60  ? 113.033 111.586 136.429 1.00 42.17  ? 13  DC  D "C4'" 1 
ATOM   6068 O  "O4'" . DC  D 2 60  ? 112.178 112.354 137.312 1.00 36.21  ? 13  DC  D "O4'" 1 
ATOM   6069 C  "C3'" . DC  D 2 60  ? 113.962 110.784 137.332 1.00 45.46  ? 13  DC  D "C3'" 1 
ATOM   6070 O  "O3'" . DC  D 2 60  ? 115.204 111.451 137.450 1.00 51.17  ? 13  DC  D "O3'" 1 
ATOM   6071 C  "C2'" . DC  D 2 60  ? 113.214 110.765 138.657 1.00 39.29  ? 13  DC  D "C2'" 1 
ATOM   6072 C  "C1'" . DC  D 2 60  ? 112.561 112.134 138.646 1.00 39.71  ? 13  DC  D "C1'" 1 
ATOM   6073 N  N1    . DC  D 2 60  ? 111.359 112.222 139.512 1.00 40.44  ? 13  DC  D N1    1 
ATOM   6074 C  C2    . DC  D 2 60  ? 111.256 113.252 140.447 1.00 38.17  ? 13  DC  D C2    1 
ATOM   6075 O  O2    . DC  D 2 60  ? 112.166 114.082 140.525 1.00 36.11  ? 13  DC  D O2    1 
ATOM   6076 N  N3    . DC  D 2 60  ? 110.157 113.311 141.238 1.00 37.64  ? 13  DC  D N3    1 
ATOM   6077 C  C4    . DC  D 2 60  ? 109.200 112.394 141.116 1.00 34.96  ? 13  DC  D C4    1 
ATOM   6078 N  N4    . DC  D 2 60  ? 108.133 112.489 141.913 1.00 32.85  ? 13  DC  D N4    1 
ATOM   6079 C  C5    . DC  D 2 60  ? 109.291 111.337 140.171 1.00 36.44  ? 13  DC  D C5    1 
ATOM   6080 C  C6    . DC  D 2 60  ? 110.380 111.287 139.402 1.00 40.92  ? 13  DC  D C6    1 
ATOM   6081 P  P     . DG  D 2 61  ? 116.573 110.662 137.179 1.00 63.71  ? 14  DG  D P     1 
ATOM   6082 O  OP1   . DG  D 2 61  ? 116.925 110.821 135.752 1.00 58.20  ? 14  DG  D OP1   1 
ATOM   6083 O  OP2   . DG  D 2 61  ? 116.422 109.314 137.758 1.00 45.36  ? 14  DG  D OP2   1 
ATOM   6084 O  "O5'" . DG  D 2 61  ? 117.643 111.436 138.074 1.00 60.01  ? 14  DG  D "O5'" 1 
ATOM   6085 C  "C5'" . DG  D 2 61  ? 117.562 112.842 138.219 1.00 50.72  ? 14  DG  D "C5'" 1 
ATOM   6086 C  "C4'" . DG  D 2 61  ? 117.928 113.257 139.632 1.00 51.26  ? 14  DG  D "C4'" 1 
ATOM   6087 O  "O4'" . DG  D 2 61  ? 116.755 113.182 140.485 1.00 49.71  ? 14  DG  D "O4'" 1 
ATOM   6088 C  "C3'" . DG  D 2 61  ? 118.989 112.393 140.304 1.00 53.79  ? 14  DG  D "C3'" 1 
ATOM   6089 O  "O3'" . DG  D 2 61  ? 119.819 113.205 141.103 1.00 63.31  ? 14  DG  D "O3'" 1 
ATOM   6090 C  "C2'" . DG  D 2 61  ? 118.156 111.440 141.156 1.00 46.97  ? 14  DG  D "C2'" 1 
ATOM   6091 C  "C1'" . DG  D 2 61  ? 117.026 112.354 141.593 1.00 48.13  ? 14  DG  D "C1'" 1 
ATOM   6092 N  N9    . DG  D 2 61  ? 115.801 111.648 141.947 1.00 44.70  ? 14  DG  D N9    1 
ATOM   6093 C  C8    . DG  D 2 61  ? 115.291 110.522 141.352 1.00 42.92  ? 14  DG  D C8    1 
ATOM   6094 N  N7    . DG  D 2 61  ? 114.168 110.122 141.878 1.00 38.33  ? 14  DG  D N7    1 
ATOM   6095 C  C5    . DG  D 2 61  ? 113.919 111.042 142.885 1.00 40.46  ? 14  DG  D C5    1 
ATOM   6096 C  C6    . DG  D 2 61  ? 112.847 111.120 143.798 1.00 42.02  ? 14  DG  D C6    1 
ATOM   6097 O  O6    . DG  D 2 61  ? 111.875 110.366 143.897 1.00 42.57  ? 14  DG  D O6    1 
ATOM   6098 N  N1    . DG  D 2 61  ? 112.976 112.208 144.654 1.00 40.09  ? 14  DG  D N1    1 
ATOM   6099 C  C2    . DG  D 2 61  ? 114.014 113.104 144.628 1.00 41.27  ? 14  DG  D C2    1 
ATOM   6100 N  N2    . DG  D 2 61  ? 113.973 114.092 145.532 1.00 45.24  ? 14  DG  D N2    1 
ATOM   6101 N  N3    . DG  D 2 61  ? 115.025 113.040 143.776 1.00 40.92  ? 14  DG  D N3    1 
ATOM   6102 C  C4    . DG  D 2 61  ? 114.912 111.987 142.938 1.00 41.87  ? 14  DG  D C4    1 
ATOM   6103 P  P     . DG  D 2 62  ? 121.387 112.890 141.229 1.00 86.33  ? 15  DG  D P     1 
ATOM   6104 O  OP1   . DG  D 2 62  ? 122.102 113.803 140.311 1.00 83.38  ? 15  DG  D OP1   1 
ATOM   6105 O  OP2   . DG  D 2 62  ? 121.570 111.427 141.111 1.00 72.60  ? 15  DG  D OP2   1 
ATOM   6106 O  "O5'" . DG  D 2 62  ? 121.725 113.312 142.729 1.00 67.16  ? 15  DG  D "O5'" 1 
ATOM   6107 C  "C5'" . DG  D 2 62  ? 121.266 114.558 143.225 1.00 58.44  ? 15  DG  D "C5'" 1 
ATOM   6108 C  "C4'" . DG  D 2 62  ? 120.929 114.465 144.701 1.00 52.28  ? 15  DG  D "C4'" 1 
ATOM   6109 O  "O4'" . DG  D 2 62  ? 119.660 113.778 144.880 1.00 48.06  ? 15  DG  D "O4'" 1 
ATOM   6110 C  "C3'" . DG  D 2 62  ? 121.937 113.694 145.552 1.00 50.04  ? 15  DG  D "C3'" 1 
ATOM   6111 O  "O3'" . DG  D 2 62  ? 122.069 114.334 146.808 1.00 51.30  ? 15  DG  D "O3'" 1 
ATOM   6112 C  "C2'" . DG  D 2 62  ? 121.267 112.330 145.689 1.00 42.15  ? 15  DG  D "C2'" 1 
ATOM   6113 C  "C1'" . DG  D 2 62  ? 119.827 112.764 145.842 1.00 43.10  ? 15  DG  D "C1'" 1 
ATOM   6114 N  N9    . DG  D 2 62  ? 118.851 111.713 145.588 1.00 47.56  ? 15  DG  D N9    1 
ATOM   6115 C  C8    . DG  D 2 62  ? 118.891 110.761 144.603 1.00 52.15  ? 15  DG  D C8    1 
ATOM   6116 N  N7    . DG  D 2 62  ? 117.864 109.957 144.619 1.00 51.92  ? 15  DG  D N7    1 
ATOM   6117 C  C5    . DG  D 2 62  ? 117.096 110.409 145.684 1.00 50.26  ? 15  DG  D C5    1 
ATOM   6118 C  C6    . DG  D 2 62  ? 115.865 109.931 146.189 1.00 45.65  ? 15  DG  D C6    1 
ATOM   6119 O  O6    . DG  D 2 62  ? 115.187 108.980 145.780 1.00 45.34  ? 15  DG  D O6    1 
ATOM   6120 N  N1    . DG  D 2 62  ? 115.430 110.678 147.280 1.00 38.87  ? 15  DG  D N1    1 
ATOM   6121 C  C2    . DG  D 2 62  ? 116.101 111.748 147.811 1.00 37.94  ? 15  DG  D C2    1 
ATOM   6122 N  N2    . DG  D 2 62  ? 115.531 112.347 148.862 1.00 34.08  ? 15  DG  D N2    1 
ATOM   6123 N  N3    . DG  D 2 62  ? 117.253 112.204 147.346 1.00 45.69  ? 15  DG  D N3    1 
ATOM   6124 C  C4    . DG  D 2 62  ? 117.689 111.489 146.286 1.00 48.63  ? 15  DG  D C4    1 
ATOM   6125 P  P     . DT  D 2 63  ? 123.315 114.004 147.761 1.00 56.27  ? 16  DT  D P     1 
ATOM   6126 O  OP1   . DT  D 2 63  ? 124.014 115.276 148.045 1.00 50.70  ? 16  DT  D OP1   1 
ATOM   6127 O  OP2   . DT  D 2 63  ? 124.044 112.874 147.151 1.00 62.11  ? 16  DT  D OP2   1 
ATOM   6128 O  "O5'" . DT  D 2 63  ? 122.635 113.487 149.108 1.00 47.09  ? 16  DT  D "O5'" 1 
ATOM   6129 C  "C5'" . DT  D 2 63  ? 121.710 112.421 149.060 1.00 42.94  ? 16  DT  D "C5'" 1 
ATOM   6130 C  "C4'" . DT  D 2 63  ? 120.826 112.415 150.285 1.00 41.46  ? 16  DT  D "C4'" 1 
ATOM   6131 O  "O4'" . DT  D 2 63  ? 119.566 111.777 149.964 1.00 39.33  ? 16  DT  D "O4'" 1 
ATOM   6132 C  "C3'" . DT  D 2 63  ? 121.398 111.654 151.467 1.00 49.13  ? 16  DT  D "C3'" 1 
ATOM   6133 O  "O3'" . DT  D 2 63  ? 121.046 112.285 152.681 1.00 50.82  ? 16  DT  D "O3'" 1 
ATOM   6134 C  "C2'" . DT  D 2 63  ? 120.753 110.283 151.336 1.00 51.00  ? 16  DT  D "C2'" 1 
ATOM   6135 C  "C1'" . DT  D 2 63  ? 119.394 110.617 150.741 1.00 45.16  ? 16  DT  D "C1'" 1 
ATOM   6136 N  N1    . DT  D 2 63  ? 118.877 109.542 149.865 1.00 45.91  ? 16  DT  D N1    1 
ATOM   6137 C  C2    . DT  D 2 63  ? 117.680 108.946 150.168 1.00 46.79  ? 16  DT  D C2    1 
ATOM   6138 O  O2    . DT  D 2 63  ? 116.999 109.267 151.123 1.00 48.58  ? 16  DT  D O2    1 
ATOM   6139 N  N3    . DT  D 2 63  ? 117.299 107.957 149.304 1.00 44.24  ? 16  DT  D N3    1 
ATOM   6140 C  C4    . DT  D 2 63  ? 117.987 107.510 148.192 1.00 45.68  ? 16  DT  D C4    1 
ATOM   6141 O  O4    . DT  D 2 63  ? 117.562 106.613 147.476 1.00 50.36  ? 16  DT  D O4    1 
ATOM   6142 C  C5    . DT  D 2 63  ? 119.240 108.173 147.935 1.00 44.07  ? 16  DT  D C5    1 
ATOM   6143 C  C7    . DT  D 2 63  ? 120.076 107.774 146.756 1.00 46.31  ? 16  DT  D C7    1 
ATOM   6144 C  C6    . DT  D 2 63  ? 119.622 109.144 148.776 1.00 44.66  ? 16  DT  D C6    1 
ATOM   6145 P  P     . DG  D 2 64  ? 122.057 112.218 153.926 1.00 66.20  ? 17  DG  D P     1 
ATOM   6146 O  OP1   . DG  D 2 64  ? 122.181 113.581 154.482 1.00 59.00  ? 17  DG  D OP1   1 
ATOM   6147 O  OP2   . DG  D 2 64  ? 123.263 111.492 153.477 1.00 62.99  ? 17  DG  D OP2   1 
ATOM   6148 O  "O5'" . DG  D 2 64  ? 121.312 111.283 154.982 1.00 54.22  ? 17  DG  D "O5'" 1 
ATOM   6149 C  "C5'" . DG  D 2 64  ? 120.298 111.819 155.812 1.00 51.98  ? 17  DG  D "C5'" 1 
ATOM   6150 C  "C4'" . DG  D 2 64  ? 119.717 110.746 156.713 1.00 52.17  ? 17  DG  D "C4'" 1 
ATOM   6151 O  "O4'" . DG  D 2 64  ? 119.034 109.756 155.904 1.00 57.54  ? 17  DG  D "O4'" 1 
ATOM   6152 C  "C3'" . DG  D 2 64  ? 120.735 109.981 157.552 1.00 58.09  ? 17  DG  D "C3'" 1 
ATOM   6153 O  "O3'" . DG  D 2 64  ? 120.181 109.689 158.827 1.00 63.12  ? 17  DG  D "O3'" 1 
ATOM   6154 C  "C2'" . DG  D 2 64  ? 120.980 108.718 156.732 1.00 60.16  ? 17  DG  D "C2'" 1 
ATOM   6155 C  "C1'" . DG  D 2 64  ? 119.628 108.487 156.073 1.00 63.66  ? 17  DG  D "C1'" 1 
ATOM   6156 N  N9    . DG  D 2 64  ? 119.731 107.855 154.762 1.00 59.66  ? 17  DG  D N9    1 
ATOM   6157 C  C8    . DG  D 2 64  ? 120.731 108.029 153.841 1.00 59.39  ? 17  DG  D C8    1 
ATOM   6158 N  N7    . DG  D 2 64  ? 120.561 107.334 152.753 1.00 56.02  ? 17  DG  D N7    1 
ATOM   6159 C  C5    . DG  D 2 64  ? 119.373 106.654 152.968 1.00 52.23  ? 17  DG  D C5    1 
ATOM   6160 C  C6    . DG  D 2 64  ? 118.684 105.748 152.135 1.00 53.47  ? 17  DG  D C6    1 
ATOM   6161 O  O6    . DG  D 2 64  ? 119.002 105.358 151.007 1.00 57.31  ? 17  DG  D O6    1 
ATOM   6162 N  N1    . DG  D 2 64  ? 117.517 105.285 152.731 1.00 55.97  ? 17  DG  D N1    1 
ATOM   6163 C  C2    . DG  D 2 64  ? 117.075 105.654 153.976 1.00 61.94  ? 17  DG  D C2    1 
ATOM   6164 N  N2    . DG  D 2 64  ? 115.925 105.104 154.387 1.00 66.24  ? 17  DG  D N2    1 
ATOM   6165 N  N3    . DG  D 2 64  ? 117.712 106.504 154.767 1.00 62.24  ? 17  DG  D N3    1 
ATOM   6166 C  C4    . DG  D 2 64  ? 118.850 106.962 154.199 1.00 56.30  ? 17  DG  D C4    1 
ATOM   6167 P  P     . DT  D 2 65  ? 121.024 108.872 159.925 1.00 63.23  ? 18  DT  D P     1 
ATOM   6168 O  OP1   . DT  D 2 65  ? 120.777 109.513 161.232 1.00 59.61  ? 18  DT  D OP1   1 
ATOM   6169 O  OP2   . DT  D 2 65  ? 122.415 108.710 159.454 1.00 66.31  ? 18  DT  D OP2   1 
ATOM   6170 O  "O5'" . DT  D 2 65  ? 120.311 107.445 159.941 1.00 69.47  ? 18  DT  D "O5'" 1 
ATOM   6171 C  "C5'" . DT  D 2 65  ? 118.896 107.376 160.036 1.00 65.75  ? 18  DT  D "C5'" 1 
ATOM   6172 C  "C4'" . DT  D 2 65  ? 118.404 105.956 159.837 1.00 70.09  ? 18  DT  D "C4'" 1 
ATOM   6173 O  "O4'" . DT  D 2 65  ? 118.604 105.557 158.455 1.00 68.23  ? 18  DT  D "O4'" 1 
ATOM   6174 C  "C3'" . DT  D 2 65  ? 119.110 104.907 160.690 1.00 81.82  ? 18  DT  D "C3'" 1 
ATOM   6175 O  "O3'" . DT  D 2 65  ? 118.167 103.970 161.167 1.00 93.38  ? 18  DT  D "O3'" 1 
ATOM   6176 C  "C2'" . DT  D 2 65  ? 120.086 104.267 159.708 1.00 82.00  ? 18  DT  D "C2'" 1 
ATOM   6177 C  "C1'" . DT  D 2 65  ? 119.290 104.328 158.417 1.00 77.45  ? 18  DT  D "C1'" 1 
ATOM   6178 N  N1    . DT  D 2 65  ? 120.137 104.295 157.193 1.00 78.74  ? 18  DT  D N1    1 
ATOM   6179 C  C2    . DT  D 2 65  ? 119.744 103.526 156.124 1.00 77.25  ? 18  DT  D C2    1 
ATOM   6180 O  O2    . DT  D 2 65  ? 118.723 102.863 156.118 1.00 77.41  ? 18  DT  D O2    1 
ATOM   6181 N  N3    . DT  D 2 65  ? 120.591 103.564 155.052 1.00 73.62  ? 18  DT  D N3    1 
ATOM   6182 C  C4    . DT  D 2 65  ? 121.769 104.276 154.943 1.00 72.66  ? 18  DT  D C4    1 
ATOM   6183 O  O4    . DT  D 2 65  ? 122.464 104.243 153.933 1.00 70.76  ? 18  DT  D O4    1 
ATOM   6184 C  C5    . DT  D 2 65  ? 122.125 105.060 156.100 1.00 72.32  ? 18  DT  D C5    1 
ATOM   6185 C  C7    . DT  D 2 65  ? 123.384 105.875 156.101 1.00 69.19  ? 18  DT  D C7    1 
ATOM   6186 C  C6    . DT  D 2 65  ? 121.302 105.030 157.157 1.00 75.42  ? 18  DT  D C6    1 
ATOM   6187 P  P     . DG  D 2 66  ? 118.376 103.263 162.593 1.00 103.26 ? 19  DG  D P     1 
ATOM   6188 O  OP1   . DG  D 2 66  ? 117.474 103.924 163.559 1.00 95.44  ? 19  DG  D OP1   1 
ATOM   6189 O  OP2   . DG  D 2 66  ? 119.829 103.201 162.860 1.00 95.45  ? 19  DG  D OP2   1 
ATOM   6190 O  "O5'" . DG  D 2 66  ? 117.854 101.775 162.349 1.00 107.52 ? 19  DG  D "O5'" 1 
ATOM   6191 C  "C5'" . DG  D 2 66  ? 116.571 101.565 161.780 1.00 106.27 ? 19  DG  D "C5'" 1 
ATOM   6192 C  "C4'" . DG  D 2 66  ? 116.563 100.322 160.911 1.00 105.06 ? 19  DG  D "C4'" 1 
ATOM   6193 O  "O4'" . DG  D 2 66  ? 117.374 100.548 159.727 1.00 98.64  ? 19  DG  D "O4'" 1 
ATOM   6194 C  "C3'" . DG  D 2 66  ? 117.126 99.067  161.575 1.00 112.59 ? 19  DG  D "C3'" 1 
ATOM   6195 O  "O3'" . DG  D 2 66  ? 116.348 97.941  161.207 1.00 116.45 ? 19  DG  D "O3'" 1 
ATOM   6196 C  "C2'" . DG  D 2 66  ? 118.538 98.984  161.004 1.00 108.25 ? 19  DG  D "C2'" 1 
ATOM   6197 C  "C1'" . DG  D 2 66  ? 118.315 99.508  159.597 1.00 103.81 ? 19  DG  D "C1'" 1 
ATOM   6198 N  N9    . DG  D 2 66  ? 119.520 100.049 158.976 1.00 99.68  ? 19  DG  D N9    1 
ATOM   6199 C  C8    . DG  D 2 66  ? 120.422 100.916 159.539 1.00 98.05  ? 19  DG  D C8    1 
ATOM   6200 N  N7    . DG  D 2 66  ? 121.405 101.231 158.743 1.00 93.68  ? 19  DG  D N7    1 
ATOM   6201 C  C5    . DG  D 2 66  ? 121.137 100.527 157.576 1.00 95.09  ? 19  DG  D C5    1 
ATOM   6202 C  C6    . DG  D 2 66  ? 121.856 100.474 156.360 1.00 94.99  ? 19  DG  D C6    1 
ATOM   6203 O  O6    . DG  D 2 66  ? 122.907 101.057 156.065 1.00 92.25  ? 19  DG  D O6    1 
ATOM   6204 N  N1    . DG  D 2 66  ? 121.238 99.638  155.433 1.00 98.48  ? 19  DG  D N1    1 
ATOM   6205 C  C2    . DG  D 2 66  ? 120.073 98.944  155.657 1.00 99.00  ? 19  DG  D C2    1 
ATOM   6206 N  N2    . DG  D 2 66  ? 119.626 98.187  154.645 1.00 99.98  ? 19  DG  D N2    1 
ATOM   6207 N  N3    . DG  D 2 66  ? 119.392 98.987  156.793 1.00 98.55  ? 19  DG  D N3    1 
ATOM   6208 C  C4    . DG  D 2 66  ? 119.980 99.796  157.704 1.00 97.95  ? 19  DG  D C4    1 
ATOM   6209 P  P     . DA  D 2 67  ? 116.289 96.649  162.160 1.00 137.26 ? 20  DA  D P     1 
ATOM   6210 O  OP1   . DA  D 2 67  ? 114.910 96.541  162.682 1.00 125.15 ? 20  DA  D OP1   1 
ATOM   6211 O  OP2   . DA  D 2 67  ? 117.430 96.724  163.099 1.00 134.25 ? 20  DA  D OP2   1 
ATOM   6212 O  "O5'" . DA  D 2 67  ? 116.558 95.432  161.160 1.00 136.22 ? 20  DA  D "O5'" 1 
ATOM   6213 C  "C5'" . DA  D 2 67  ? 115.767 95.297  159.989 1.00 130.29 ? 20  DA  D "C5'" 1 
ATOM   6214 C  "C4'" . DA  D 2 67  ? 116.546 94.605  158.886 1.00 130.61 ? 20  DA  D "C4'" 1 
ATOM   6215 O  "O4'" . DA  D 2 67  ? 117.623 95.465  158.435 1.00 123.23 ? 20  DA  D "O4'" 1 
ATOM   6216 C  "C3'" . DA  D 2 67  ? 117.191 93.277  159.283 1.00 134.14 ? 20  DA  D "C3'" 1 
ATOM   6217 O  "O3'" . DA  D 2 67  ? 116.935 92.306  158.278 1.00 142.80 ? 20  DA  D "O3'" 1 
ATOM   6218 C  "C2'" . DA  D 2 67  ? 118.680 93.615  159.381 1.00 130.94 ? 20  DA  D "C2'" 1 
ATOM   6219 C  "C1'" . DA  D 2 67  ? 118.816 94.726  158.356 1.00 124.19 ? 20  DA  D "C1'" 1 
ATOM   6220 N  N9    . DA  D 2 67  ? 119.929 95.630  158.621 1.00 116.95 ? 20  DA  D N9    1 
ATOM   6221 C  C8    . DA  D 2 67  ? 120.200 96.279  159.791 1.00 114.43 ? 20  DA  D C8    1 
ATOM   6222 N  N7    . DA  D 2 67  ? 121.268 97.039  159.739 1.00 107.59 ? 20  DA  D N7    1 
ATOM   6223 C  C5    . DA  D 2 67  ? 121.727 96.878  158.444 1.00 111.70 ? 20  DA  D C5    1 
ATOM   6224 C  C6    . DA  D 2 67  ? 122.828 97.419  157.755 1.00 112.02 ? 20  DA  D C6    1 
ATOM   6225 N  N6    . DA  D 2 67  ? 123.699 98.265  158.310 1.00 108.98 ? 20  DA  D N6    1 
ATOM   6226 N  N1    . DA  D 2 67  ? 123.003 97.052  156.467 1.00 115.18 ? 20  DA  D N1    1 
ATOM   6227 C  C2    . DA  D 2 67  ? 122.128 96.204  155.916 1.00 116.78 ? 20  DA  D C2    1 
ATOM   6228 N  N3    . DA  D 2 67  ? 121.057 95.632  156.463 1.00 120.24 ? 20  DA  D N3    1 
ATOM   6229 C  C4    . DA  D 2 67  ? 120.912 96.015  157.740 1.00 117.35 ? 20  DA  D C4    1 
ATOM   6230 P  P     . DA  D 2 68  ? 117.325 90.765  158.506 1.00 152.56 ? 21  DA  D P     1 
ATOM   6231 O  OP1   . DA  D 2 68  ? 116.142 89.951  158.154 1.00 147.73 ? 21  DA  D OP1   1 
ATOM   6232 O  OP2   . DA  D 2 68  ? 117.934 90.626  159.848 1.00 147.09 ? 21  DA  D OP2   1 
ATOM   6233 O  "O5'" . DA  D 2 68  ? 118.461 90.507  157.415 1.00 148.02 ? 21  DA  D "O5'" 1 
ATOM   6234 C  "C5'" . DA  D 2 68  ? 118.265 90.946  156.075 1.00 145.43 ? 21  DA  D "C5'" 1 
ATOM   6235 C  "C4'" . DA  D 2 68  ? 119.566 90.895  155.298 1.00 145.73 ? 21  DA  D "C4'" 1 
ATOM   6236 O  "O4'" . DA  D 2 68  ? 120.408 92.017  155.683 1.00 139.64 ? 21  DA  D "O4'" 1 
ATOM   6237 C  "C3'" . DA  D 2 68  ? 120.402 89.636  155.533 1.00 153.87 ? 21  DA  D "C3'" 1 
ATOM   6238 O  "O3'" . DA  D 2 68  ? 120.955 89.182  154.305 1.00 163.53 ? 21  DA  D "O3'" 1 
ATOM   6239 C  "C2'" . DA  D 2 68  ? 121.486 90.121  156.489 1.00 148.80 ? 21  DA  D "C2'" 1 
ATOM   6240 C  "C1'" . DA  D 2 68  ? 121.694 91.542  155.998 1.00 142.14 ? 21  DA  D "C1'" 1 
ATOM   6241 N  N9    . DA  D 2 68  ? 122.292 92.420  156.999 1.00 135.21 ? 21  DA  D N9    1 
ATOM   6242 C  C8    . DA  D 2 68  ? 121.879 92.598  158.289 1.00 132.87 ? 21  DA  D C8    1 
ATOM   6243 N  N7    . DA  D 2 68  ? 122.613 93.447  158.966 1.00 129.95 ? 21  DA  D N7    1 
ATOM   6244 C  C5    . DA  D 2 68  ? 123.576 93.854  158.060 1.00 130.67 ? 21  DA  D C5    1 
ATOM   6245 C  C6    . DA  D 2 68  ? 124.655 94.752  158.163 1.00 131.96 ? 21  DA  D C6    1 
ATOM   6246 N  N6    . DA  D 2 68  ? 124.946 95.423  159.279 1.00 132.67 ? 21  DA  D N6    1 
ATOM   6247 N  N1    . DA  D 2 68  ? 125.426 94.933  157.070 1.00 133.90 ? 21  DA  D N1    1 
ATOM   6248 C  C2    . DA  D 2 68  ? 125.129 94.260  155.952 1.00 134.30 ? 21  DA  D C2    1 
ATOM   6249 N  N3    . DA  D 2 68  ? 124.141 93.389  155.737 1.00 136.19 ? 21  DA  D N3    1 
ATOM   6250 C  C4    . DA  D 2 68  ? 123.395 93.230  156.842 1.00 134.57 ? 21  DA  D C4    1 
ATOM   6251 P  P     . DG  D 2 69  ? 121.482 87.670  154.162 1.00 170.93 ? 22  DG  D P     1 
ATOM   6252 O  OP1   . DG  D 2 69  ? 120.560 86.968  153.242 1.00 168.64 ? 22  DG  D OP1   1 
ATOM   6253 O  OP2   . DG  D 2 69  ? 121.707 87.129  155.520 1.00 159.92 ? 22  DG  D OP2   1 
ATOM   6254 O  "O5'" . DG  D 2 69  ? 122.907 87.829  153.451 1.00 169.28 ? 22  DG  D "O5'" 1 
ATOM   6255 C  "C5'" . DG  D 2 69  ? 122.987 88.390  152.146 1.00 167.32 ? 22  DG  D "C5'" 1 
ATOM   6256 C  "C4'" . DG  D 2 69  ? 124.367 88.969  151.872 1.00 168.85 ? 22  DG  D "C4'" 1 
ATOM   6257 O  "O4'" . DG  D 2 69  ? 124.675 90.002  152.844 1.00 163.58 ? 22  DG  D "O4'" 1 
ATOM   6258 C  "C3'" . DG  D 2 69  ? 125.527 87.982  151.939 1.00 175.69 ? 22  DG  D "C3'" 1 
ATOM   6259 O  "O3'" . DG  D 2 69  ? 126.508 88.364  150.985 1.00 181.90 ? 22  DG  D "O3'" 1 
ATOM   6260 C  "C2'" . DG  D 2 69  ? 126.030 88.167  153.370 1.00 171.59 ? 22  DG  D "C2'" 1 
ATOM   6261 C  "C1'" . DG  D 2 69  ? 125.860 89.667  153.541 1.00 166.14 ? 22  DG  D "C1'" 1 
ATOM   6262 N  N9    . DG  D 2 69  ? 125.696 90.102  154.921 1.00 157.30 ? 22  DG  D N9    1 
ATOM   6263 C  C8    . DG  D 2 69  ? 124.695 89.741  155.784 1.00 154.19 ? 22  DG  D C8    1 
ATOM   6264 N  N7    . DG  D 2 69  ? 124.785 90.312  156.952 1.00 152.89 ? 22  DG  D N7    1 
ATOM   6265 C  C5    . DG  D 2 69  ? 125.916 91.109  156.855 1.00 154.02 ? 22  DG  D C5    1 
ATOM   6266 C  C6    . DG  D 2 69  ? 126.511 91.967  157.811 1.00 151.45 ? 22  DG  D C6    1 
ATOM   6267 O  O6    . DG  D 2 69  ? 126.142 92.190  158.971 1.00 148.86 ? 22  DG  D O6    1 
ATOM   6268 N  N1    . DG  D 2 69  ? 127.648 92.595  157.304 1.00 151.34 ? 22  DG  D N1    1 
ATOM   6269 C  C2    . DG  D 2 69  ? 128.141 92.416  156.034 1.00 154.64 ? 22  DG  D C2    1 
ATOM   6270 N  N2    . DG  D 2 69  ? 129.248 93.105  155.722 1.00 152.53 ? 22  DG  D N2    1 
ATOM   6271 N  N3    . DG  D 2 69  ? 127.590 91.616  155.129 1.00 158.93 ? 22  DG  D N3    1 
ATOM   6272 C  C4    . DG  D 2 69  ? 126.484 90.999  155.607 1.00 156.37 ? 22  DG  D C4    1 
ATOM   6273 P  P     . DA  D 2 70  ? 127.724 87.388  150.602 1.00 187.14 ? 23  DA  D P     1 
ATOM   6274 O  OP1   . DA  D 2 70  ? 127.554 87.004  149.184 1.00 182.74 ? 23  DA  D OP1   1 
ATOM   6275 O  OP2   . DA  D 2 70  ? 127.845 86.336  151.636 1.00 180.41 ? 23  DA  D OP2   1 
ATOM   6276 O  "O5'" . DA  D 2 70  ? 129.002 88.338  150.715 1.00 181.71 ? 23  DA  D "O5'" 1 
ATOM   6277 C  "C5'" . DA  D 2 70  ? 129.197 89.131  151.880 1.00 176.21 ? 23  DA  D "C5'" 1 
ATOM   6278 C  "C4'" . DA  D 2 70  ? 130.636 89.593  151.965 1.00 178.36 ? 23  DA  D "C4'" 1 
ATOM   6279 O  "O4'" . DA  D 2 70  ? 130.860 90.274  153.220 1.00 174.64 ? 23  DA  D "O4'" 1 
ATOM   6280 C  "C3'" . DA  D 2 70  ? 131.649 88.479  151.967 1.00 184.46 ? 23  DA  D "C3'" 1 
ATOM   6281 O  "O3'" . DA  D 2 70  ? 132.909 89.009  151.609 1.00 187.58 ? 23  DA  D "O3'" 1 
ATOM   6282 C  "C2'" . DA  D 2 70  ? 131.611 88.037  153.432 1.00 181.60 ? 23  DA  D "C2'" 1 
ATOM   6283 C  "C1'" . DA  D 2 70  ? 131.412 89.368  154.165 1.00 176.13 ? 23  DA  D "C1'" 1 
ATOM   6284 N  N9    . DA  D 2 70  ? 130.485 89.308  155.293 1.00 170.85 ? 23  DA  D N9    1 
ATOM   6285 C  C8    . DA  D 2 70  ? 129.337 88.572  155.377 1.00 166.86 ? 23  DA  D C8    1 
ATOM   6286 N  N7    . DA  D 2 70  ? 128.679 88.747  156.498 1.00 163.25 ? 23  DA  D N7    1 
ATOM   6287 C  C5    . DA  D 2 70  ? 129.440 89.672  157.193 1.00 164.34 ? 23  DA  D C5    1 
ATOM   6288 C  C6    . DA  D 2 70  ? 129.279 90.275  158.457 1.00 161.96 ? 23  DA  D C6    1 
ATOM   6289 N  N6    . DA  D 2 70  ? 128.251 90.014  159.266 1.00 160.54 ? 23  DA  D N6    1 
ATOM   6290 N  N1    . DA  D 2 70  ? 130.219 91.159  158.855 1.00 162.26 ? 23  DA  D N1    1 
ATOM   6291 C  C2    . DA  D 2 70  ? 131.248 91.413  158.038 1.00 162.80 ? 23  DA  D C2    1 
ATOM   6292 N  N3    . DA  D 2 70  ? 131.505 90.910  156.827 1.00 165.02 ? 23  DA  D N3    1 
ATOM   6293 C  C4    . DA  D 2 70  ? 130.552 90.036  156.462 1.00 167.52 ? 23  DA  D C4    1 
ATOM   6294 P  P     . DC  D 2 71  ? 134.112 88.047  151.161 1.00 193.76 ? 24  DC  D P     1 
ATOM   6295 O  OP1   . DC  D 2 71  ? 134.342 88.258  149.714 1.00 191.61 ? 24  DC  D OP1   1 
ATOM   6296 O  OP2   . DC  D 2 71  ? 133.833 86.684  151.666 1.00 189.29 ? 24  DC  D OP2   1 
ATOM   6297 O  "O5'" . DC  D 2 71  ? 135.353 88.636  151.972 1.00 190.63 ? 24  DC  D "O5'" 1 
ATOM   6298 C  "C5'" . DC  D 2 71  ? 135.126 89.316  153.204 1.00 186.65 ? 24  DC  D "C5'" 1 
ATOM   6299 C  "C4'" . DC  D 2 71  ? 135.825 88.602  154.339 1.00 186.61 ? 24  DC  D "C4'" 1 
ATOM   6300 O  "O4'" . DC  D 2 71  ? 134.937 88.524  155.491 1.00 181.65 ? 24  DC  D "O4'" 1 
ATOM   6301 C  "C3'" . DC  D 2 71  ? 136.230 87.164  154.024 1.00 189.60 ? 24  DC  D "C3'" 1 
ATOM   6302 O  "O3'" . DC  D 2 71  ? 137.486 86.873  154.625 1.00 192.89 ? 24  DC  D "O3'" 1 
ATOM   6303 C  "C2'" . DC  D 2 71  ? 135.101 86.358  154.658 1.00 187.05 ? 24  DC  D "C2'" 1 
ATOM   6304 C  "C1'" . DC  D 2 71  ? 134.832 87.181  155.906 1.00 184.65 ? 24  DC  D "C1'" 1 
ATOM   6305 N  N1    . DC  D 2 71  ? 133.475 86.959  156.499 1.00 179.67 ? 24  DC  D N1    1 
ATOM   6306 C  C2    . DC  D 2 71  ? 133.085 87.682  157.633 1.00 176.02 ? 24  DC  D C2    1 
ATOM   6307 O  O2    . DC  D 2 71  ? 133.868 88.490  158.142 1.00 174.41 ? 24  DC  D O2    1 
ATOM   6308 N  N3    . DC  D 2 71  ? 131.860 87.461  158.166 1.00 174.73 ? 24  DC  D N3    1 
ATOM   6309 C  C4    . DC  D 2 71  ? 131.036 86.579  157.600 1.00 172.70 ? 24  DC  D C4    1 
ATOM   6310 N  N4    . DC  D 2 71  ? 129.837 86.403  158.160 1.00 169.84 ? 24  DC  D N4    1 
ATOM   6311 C  C5    . DC  D 2 71  ? 131.412 85.831  156.445 1.00 172.49 ? 24  DC  D C5    1 
ATOM   6312 C  C6    . DC  D 2 71  ? 132.631 86.048  155.936 1.00 176.91 ? 24  DC  D C6    1 
ATOM   6313 P  P     . DC  D 2 72  ? 138.847 87.044  153.787 1.00 196.39 ? 25  DC  D P     1 
ATOM   6314 O  OP1   . DC  D 2 72  ? 138.690 88.193  152.869 1.00 191.71 ? 25  DC  D OP1   1 
ATOM   6315 O  OP2   . DC  D 2 72  ? 139.207 85.716  153.244 1.00 191.96 ? 25  DC  D OP2   1 
ATOM   6316 O  "O5'" . DC  D 2 72  ? 139.931 87.425  154.899 1.00 196.46 ? 25  DC  D "O5'" 1 
ATOM   6317 C  "C5'" . DC  D 2 72  ? 139.708 88.539  155.758 1.00 193.09 ? 25  DC  D "C5'" 1 
ATOM   6318 C  "C4'" . DC  D 2 72  ? 139.725 88.110  157.215 1.00 189.48 ? 25  DC  D "C4'" 1 
ATOM   6319 O  "O4'" . DC  D 2 72  ? 138.412 87.616  157.596 1.00 187.90 ? 25  DC  D "O4'" 1 
ATOM   6320 C  "C3'" . DC  D 2 72  ? 140.709 86.987  157.548 1.00 191.42 ? 25  DC  D "C3'" 1 
ATOM   6321 O  "O3'" . DC  D 2 72  ? 141.324 87.238  158.804 1.00 194.46 ? 25  DC  D "O3'" 1 
ATOM   6322 C  "C2'" . DC  D 2 72  ? 139.809 85.756  157.609 1.00 189.01 ? 25  DC  D "C2'" 1 
ATOM   6323 C  "C1'" . DC  D 2 72  ? 138.554 86.356  158.212 1.00 187.79 ? 25  DC  D "C1'" 1 
ATOM   6324 N  N1    . DC  D 2 72  ? 137.320 85.558  157.965 1.00 185.72 ? 25  DC  D N1    1 
ATOM   6325 C  C2    . DC  D 2 72  ? 136.208 85.734  158.795 1.00 182.01 ? 25  DC  D C2    1 
ATOM   6326 O  O2    . DC  D 2 72  ? 136.270 86.536  159.729 1.00 178.36 ? 25  DC  D O2    1 
ATOM   6327 N  N3    . DC  D 2 72  ? 135.093 84.999  158.570 1.00 180.69 ? 25  DC  D N3    1 
ATOM   6328 C  C4    . DC  D 2 72  ? 135.059 84.136  157.556 1.00 180.14 ? 25  DC  D C4    1 
ATOM   6329 N  N4    . DC  D 2 72  ? 133.933 83.440  157.370 1.00 178.62 ? 25  DC  D N4    1 
ATOM   6330 C  C5    . DC  D 2 72  ? 136.182 83.938  156.697 1.00 181.08 ? 25  DC  D C5    1 
ATOM   6331 C  C6    . DC  D 2 72  ? 137.280 84.666  156.933 1.00 184.43 ? 25  DC  D C6    1 
ATOM   6332 P  P     . DC  D 2 73  ? 142.628 86.410  159.240 1.00 201.83 ? 26  DC  D P     1 
ATOM   6333 O  OP1   . DC  D 2 73  ? 143.312 87.177  160.303 1.00 197.43 ? 26  DC  D OP1   1 
ATOM   6334 O  OP2   . DC  D 2 73  ? 143.356 86.048  158.003 1.00 196.11 ? 26  DC  D OP2   1 
ATOM   6335 O  "O5'" . DC  D 2 73  ? 142.040 85.060  159.867 1.00 195.52 ? 26  DC  D "O5'" 1 
ATOM   6336 C  "C5'" . DC  D 2 73  ? 141.957 84.903  161.282 1.00 191.73 ? 26  DC  D "C5'" 1 
ATOM   6337 C  "C4'" . DC  D 2 73  ? 140.573 85.266  161.790 1.00 188.93 ? 26  DC  D "C4'" 1 
ATOM   6338 O  "O4'" . DC  D 2 73  ? 139.587 84.939  160.779 1.00 189.47 ? 26  DC  D "O4'" 1 
ATOM   6339 C  "C3'" . DC  D 2 73  ? 140.132 84.522  163.043 1.00 184.10 ? 26  DC  D "C3'" 1 
ATOM   6340 O  "O3'" . DC  D 2 73  ? 139.247 85.335  163.802 1.00 179.23 ? 26  DC  D "O3'" 1 
ATOM   6341 C  "C2'" . DC  D 2 73  ? 139.414 83.309  162.462 1.00 182.64 ? 26  DC  D "C2'" 1 
ATOM   6342 C  "C1'" . DC  D 2 73  ? 138.724 83.925  161.253 1.00 185.00 ? 26  DC  D "C1'" 1 
ATOM   6343 N  N1    . DC  D 2 73  ? 138.484 82.960  160.142 1.00 184.83 ? 26  DC  D N1    1 
ATOM   6344 C  C2    . DC  D 2 73  ? 137.213 82.403  159.970 1.00 181.71 ? 26  DC  D C2    1 
ATOM   6345 O  O2    . DC  D 2 73  ? 136.305 82.718  160.748 1.00 180.28 ? 26  DC  D O2    1 
ATOM   6346 N  N3    . DC  D 2 73  ? 137.012 81.529  158.952 1.00 180.02 ? 26  DC  D N3    1 
ATOM   6347 C  C4    . DC  D 2 73  ? 138.018 81.215  158.133 1.00 180.37 ? 26  DC  D C4    1 
ATOM   6348 N  N4    . DC  D 2 73  ? 137.773 80.349  157.144 1.00 177.97 ? 26  DC  D N4    1 
ATOM   6349 C  C5    . DC  D 2 73  ? 139.320 81.775  158.292 1.00 182.05 ? 26  DC  D C5    1 
ATOM   6350 C  C6    . DC  D 2 73  ? 139.506 82.634  159.299 1.00 184.89 ? 26  DC  D C6    1 
HETATM 6351 MG MG    . MG  E 3 .   ? 104.752 108.981 154.567 1.00 46.43  ? 401 MG  A MG    1 
HETATM 6352 MG MG    . MG  F 3 .   ? 105.881 107.483 133.499 1.00 50.42  ? 401 MG  B MG    1 
HETATM 6353 O  O     . HOH G 4 .   ? 137.260 119.639 147.380 1.00 28.86  ? 501 HOH A O     1 
HETATM 6354 O  O     . HOH G 4 .   ? 107.310 104.169 156.251 1.00 61.02  ? 502 HOH A O     1 
HETATM 6355 O  O     . HOH G 4 .   ? 99.467  123.635 157.247 1.00 63.08  ? 503 HOH A O     1 
HETATM 6356 O  O     . HOH G 4 .   ? 134.754 118.433 154.091 1.00 41.94  ? 504 HOH A O     1 
HETATM 6357 O  O     . HOH H 4 .   ? 105.147 117.308 124.821 1.00 63.68  ? 501 HOH B O     1 
HETATM 6358 O  O     . HOH H 4 .   ? 120.024 101.217 129.803 1.00 66.25  ? 502 HOH B O     1 
HETATM 6359 O  O     . HOH H 4 .   ? 101.617 110.615 131.664 1.00 61.69  ? 503 HOH B O     1 
HETATM 6360 O  O     . HOH H 4 .   ? 118.791 136.136 133.981 1.00 43.73  ? 504 HOH B O     1 
HETATM 6361 O  O     . HOH H 4 .   ? 94.620  94.730  144.190 1.00 56.09  ? 505 HOH B O     1 
# 
