data_9BFP
# 
_entry.id   9BFP 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BFP         pdb_00009bfp 10.2210/pdb9bfp/pdb 
WWPDB D_1000282912 ?            ?                   
EMDB  EMD-44502    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-01-29 ? 
2 'EM metadata'     1 0 2025-01-29 ? 
3 'Additional map'  1 0 2025-01-29 ? 
4 'Half map'        1 0 2025-01-29 1 
5 'Half map'        1 0 2025-01-29 2 
6 Image             1 0 2025-01-29 ? 
7 'Primary map'     1 0 2025-01-29 ? 
8 'Structure model' 1 1 2025-05-14 ? 
9 'EM metadata'     1 1 2025-05-14 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 'Additional map'  repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'      
2 9 'EM metadata'     'Data processing'      
3 9 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' em_admin    
2 8 'Structure model' em_software 
3 9 'EM metadata'     em_admin    
4 9 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 8 'Structure model' '_em_admin.last_update' 
2 8 'Structure model' '_em_software.name'     
3 9 'EM metadata'     '_em_admin.last_update' 
4 9 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BFP 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
PDB  'Sevenless dimer at pH 6.6'                                     9BFS      unspecified            
PDB  'Sevenless dimer at pH 4.6'                                     9BFU      unspecified            
PDB  'Sevenless in complex with Bride of Sevenless'                  9BFQ      unspecified            
PDB  'Bride of Sevenless'                                            9BFR      unspecified            
EMDB 'Cryo-EM structure of Sevenless extracellular domain (monomer)' EMD-44502 'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              lss8@columbia.edu 
_pdbx_contact_author.name_first         Lawrence 
_pdbx_contact_author.name_last          Shapiro 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0001-9943-8819 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Cerutti, G.' 1 0000-0002-9081-7561 
'Shapiro, L.' 2 0000-0001-9943-8819 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   US 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            Mol.Cell 
_citation.journal_id_ASTM           MOCEFL 
_citation.journal_id_CSD            2168 
_citation.journal_id_ISSN           1097-2765 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            84 
_citation.language                  ? 
_citation.page_first                4677 
_citation.page_last                 4690.e6 
_citation.title                     'Structures and pH-dependent dimerization of the sevenless receptor tyrosine kinase.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1016/j.molcel.2024.10.017 
_citation.pdbx_database_id_PubMed   39510067 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Cerutti, G.'    1  ? 
primary 'Arias, R.'      2  ? 
primary 'Bahna, F.'      3  ? 
primary 'Mannepalli, S.' 4  ? 
primary 'Katsamba, P.S.' 5  ? 
primary 'Ahlsen, G.'     6  ? 
primary 'Kloss, B.'      7  ? 
primary 'Bruni, R.'      8  ? 
primary 'Tomlinson, A.'  9  ? 
primary 'Shapiro, L.'    10 ? 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Protein sevenless'                                                                       225292.922 1 2.7.10.1 
? ? ? 
2 branched    man '2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose' 424.401    1 ?        
? ? ? 
3 non-polymer syn 2-acetamido-2-deoxy-beta-D-glucopyranose                                                  221.208    2 ?        
? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;DVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAISSRPQSTMAHHPDDRDRDRDPSE
EQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCEKADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPY
DMPCIGACEMAQRDYWHLQRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELD
LEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPV
IEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVA
KGFVQTHSARNEKPAKDLTESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFESG
QMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLGESAQKVGESFDLPVEQLEVDAL
NGWIFWRNEESLWRQDLHGRMIHRLLRIRQPGWFLVQPQHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPA
SSHWQSFALLGRSLLLPDSGQLILVEQQGQAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAAKI
SWKEPERNPYQSADAARSWSYELEVLDVASQSAFSIRNIRGPIFGLQRLQPDNLYQLRVRAINVDGEPGEWTEPLAARTW
PLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGS
VTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLPVFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLEGS
IASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLRPLGALLWLERSGRRARLVRLAA
PLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQR
LQTLDLSTPFARLTQLPQAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRWDA
PEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPDQTYHFQVEARVAATGAAAGAASHALHVAPEVQAVP
RVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAPAKLARMRAEVLALAVDWIQR
IVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGS
ELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSI
RAYGRRRQQLEYTVELEPEEVRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLNLPMITASEDCPLPIPGVRY
QLNLTLARGPGSEEHDHGVEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPSPP
RNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAH
ATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTPDPLGSLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRY
QCRLLLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDINSGGS
LEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSHHHHHHWSHPQF
EK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;DVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAISSRPQSTMAHHPDDRDRDRDPSE
EQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCEKADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPY
DMPCIGACEMAQRDYWHLQRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELD
LEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPV
IEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVA
KGFVQTHSARNEKPAKDLTESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFESG
QMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLGESAQKVGESFDLPVEQLEVDAL
NGWIFWRNEESLWRQDLHGRMIHRLLRIRQPGWFLVQPQHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPA
SSHWQSFALLGRSLLLPDSGQLILVEQQGQAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAAKI
SWKEPERNPYQSADAARSWSYELEVLDVASQSAFSIRNIRGPIFGLQRLQPDNLYQLRVRAINVDGEPGEWTEPLAARTW
PLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGS
VTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLPVFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLEGS
IASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLRPLGALLWLERSGRRARLVRLAA
PLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQR
LQTLDLSTPFARLTQLPQAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRWDA
PEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPDQTYHFQVEARVAATGAAAGAASHALHVAPEVQAVP
RVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAPAKLARMRAEVLALAVDWIQR
IVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGS
ELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSI
RAYGRRRQQLEYTVELEPEEVRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLNLPMITASEDCPLPIPGVRY
QLNLTLARGPGSEEHDHGVEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPSPP
RNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAH
ATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTPDPLGSLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRY
QCRLLLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDINSGGS
LEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVSHHHHHHWSHPQF
EK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        2-acetamido-2-deoxy-beta-D-glucopyranose 
_pdbx_entity_nonpoly.comp_id     NAG 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    ASP n 
1 2    VAL n 
1 3    CYS n 
1 4    ARG n 
1 5    SER n 
1 6    HIS n 
1 7    ASN n 
1 8    TYR n 
1 9    THR n 
1 10   VAL n 
1 11   HIS n 
1 12   GLN n 
1 13   SER n 
1 14   PRO n 
1 15   GLU n 
1 16   PRO n 
1 17   VAL n 
1 18   SER n 
1 19   LYS n 
1 20   ASP n 
1 21   GLN n 
1 22   MET n 
1 23   ARG n 
1 24   LEU n 
1 25   LEU n 
1 26   ARG n 
1 27   PRO n 
1 28   LYS n 
1 29   LEU n 
1 30   ASP n 
1 31   SER n 
1 32   ASP n 
1 33   VAL n 
1 34   VAL n 
1 35   GLU n 
1 36   LYS n 
1 37   VAL n 
1 38   ALA n 
1 39   ILE n 
1 40   TRP n 
1 41   HIS n 
1 42   LYS n 
1 43   HIS n 
1 44   ALA n 
1 45   ALA n 
1 46   ALA n 
1 47   ALA n 
1 48   PRO n 
1 49   PRO n 
1 50   SER n 
1 51   ILE n 
1 52   VAL n 
1 53   GLU n 
1 54   GLY n 
1 55   ILE n 
1 56   ALA n 
1 57   ILE n 
1 58   SER n 
1 59   SER n 
1 60   ARG n 
1 61   PRO n 
1 62   GLN n 
1 63   SER n 
1 64   THR n 
1 65   MET n 
1 66   ALA n 
1 67   HIS n 
1 68   HIS n 
1 69   PRO n 
1 70   ASP n 
1 71   ASP n 
1 72   ARG n 
1 73   ASP n 
1 74   ARG n 
1 75   ASP n 
1 76   ARG n 
1 77   ASP n 
1 78   PRO n 
1 79   SER n 
1 80   GLU n 
1 81   GLU n 
1 82   GLN n 
1 83   HIS n 
1 84   GLY n 
1 85   VAL n 
1 86   ASP n 
1 87   GLU n 
1 88   ARG n 
1 89   MET n 
1 90   VAL n 
1 91   LEU n 
1 92   GLU n 
1 93   ARG n 
1 94   VAL n 
1 95   THR n 
1 96   ARG n 
1 97   ASP n 
1 98   CYS n 
1 99   VAL n 
1 100  GLN n 
1 101  ARG n 
1 102  CYS n 
1 103  ILE n 
1 104  VAL n 
1 105  GLU n 
1 106  GLU n 
1 107  ASP n 
1 108  LEU n 
1 109  PHE n 
1 110  LEU n 
1 111  ASP n 
1 112  GLU n 
1 113  PHE n 
1 114  GLY n 
1 115  ILE n 
1 116  GLN n 
1 117  CYS n 
1 118  GLU n 
1 119  LYS n 
1 120  ALA n 
1 121  ASP n 
1 122  ASN n 
1 123  GLY n 
1 124  GLU n 
1 125  LYS n 
1 126  CYS n 
1 127  TYR n 
1 128  LYS n 
1 129  THR n 
1 130  ARG n 
1 131  CYS n 
1 132  THR n 
1 133  LYS n 
1 134  GLY n 
1 135  CYS n 
1 136  ALA n 
1 137  GLN n 
1 138  TRP n 
1 139  TYR n 
1 140  ARG n 
1 141  ALA n 
1 142  LEU n 
1 143  LYS n 
1 144  GLU n 
1 145  LEU n 
1 146  GLU n 
1 147  SER n 
1 148  CYS n 
1 149  GLN n 
1 150  GLU n 
1 151  ALA n 
1 152  CYS n 
1 153  LEU n 
1 154  SER n 
1 155  LEU n 
1 156  GLN n 
1 157  PHE n 
1 158  TYR n 
1 159  PRO n 
1 160  TYR n 
1 161  ASP n 
1 162  MET n 
1 163  PRO n 
1 164  CYS n 
1 165  ILE n 
1 166  GLY n 
1 167  ALA n 
1 168  CYS n 
1 169  GLU n 
1 170  MET n 
1 171  ALA n 
1 172  GLN n 
1 173  ARG n 
1 174  ASP n 
1 175  TYR n 
1 176  TRP n 
1 177  HIS n 
1 178  LEU n 
1 179  GLN n 
1 180  ARG n 
1 181  LEU n 
1 182  ALA n 
1 183  ILE n 
1 184  SER n 
1 185  HIS n 
1 186  LEU n 
1 187  VAL n 
1 188  GLU n 
1 189  ARG n 
1 190  THR n 
1 191  GLN n 
1 192  PRO n 
1 193  GLN n 
1 194  LEU n 
1 195  GLU n 
1 196  ARG n 
1 197  ALA n 
1 198  PRO n 
1 199  ARG n 
1 200  ALA n 
1 201  ASP n 
1 202  GLY n 
1 203  GLN n 
1 204  SER n 
1 205  THR n 
1 206  PRO n 
1 207  LEU n 
1 208  THR n 
1 209  ILE n 
1 210  ARG n 
1 211  TRP n 
1 212  ALA n 
1 213  MET n 
1 214  HIS n 
1 215  PHE n 
1 216  PRO n 
1 217  GLU n 
1 218  HIS n 
1 219  TYR n 
1 220  LEU n 
1 221  ALA n 
1 222  SER n 
1 223  ARG n 
1 224  PRO n 
1 225  PHE n 
1 226  ASN n 
1 227  ILE n 
1 228  GLN n 
1 229  TYR n 
1 230  GLN n 
1 231  PHE n 
1 232  VAL n 
1 233  ASP n 
1 234  HIS n 
1 235  HIS n 
1 236  GLY n 
1 237  GLU n 
1 238  GLU n 
1 239  LEU n 
1 240  ASP n 
1 241  LEU n 
1 242  GLU n 
1 243  GLN n 
1 244  GLU n 
1 245  ASP n 
1 246  GLN n 
1 247  ASP n 
1 248  ALA n 
1 249  SER n 
1 250  GLY n 
1 251  GLU n 
1 252  THR n 
1 253  GLY n 
1 254  SER n 
1 255  SER n 
1 256  ALA n 
1 257  TRP n 
1 258  PHE n 
1 259  ASN n 
1 260  LEU n 
1 261  ALA n 
1 262  ASP n 
1 263  TYR n 
1 264  ASP n 
1 265  CYS n 
1 266  ASP n 
1 267  GLU n 
1 268  TYR n 
1 269  TYR n 
1 270  VAL n 
1 271  CYS n 
1 272  GLU n 
1 273  ILE n 
1 274  LEU n 
1 275  GLU n 
1 276  ALA n 
1 277  LEU n 
1 278  ILE n 
1 279  PRO n 
1 280  TYR n 
1 281  THR n 
1 282  GLN n 
1 283  TYR n 
1 284  ARG n 
1 285  PHE n 
1 286  ARG n 
1 287  PHE n 
1 288  GLU n 
1 289  LEU n 
1 290  PRO n 
1 291  PHE n 
1 292  GLY n 
1 293  GLU n 
1 294  ASN n 
1 295  ARG n 
1 296  ASP n 
1 297  GLU n 
1 298  VAL n 
1 299  LEU n 
1 300  TYR n 
1 301  SER n 
1 302  PRO n 
1 303  ALA n 
1 304  THR n 
1 305  PRO n 
1 306  ALA n 
1 307  TYR n 
1 308  GLN n 
1 309  THR n 
1 310  PRO n 
1 311  PRO n 
1 312  GLU n 
1 313  GLY n 
1 314  ALA n 
1 315  PRO n 
1 316  ILE n 
1 317  SER n 
1 318  ALA n 
1 319  PRO n 
1 320  VAL n 
1 321  ILE n 
1 322  GLU n 
1 323  HIS n 
1 324  LEU n 
1 325  MET n 
1 326  GLY n 
1 327  LEU n 
1 328  ASP n 
1 329  ASP n 
1 330  SER n 
1 331  HIS n 
1 332  LEU n 
1 333  ALA n 
1 334  VAL n 
1 335  HIS n 
1 336  TRP n 
1 337  HIS n 
1 338  PRO n 
1 339  GLY n 
1 340  ARG n 
1 341  PHE n 
1 342  THR n 
1 343  ASN n 
1 344  GLY n 
1 345  PRO n 
1 346  ILE n 
1 347  GLU n 
1 348  GLY n 
1 349  TYR n 
1 350  ARG n 
1 351  LEU n 
1 352  ARG n 
1 353  LEU n 
1 354  SER n 
1 355  SER n 
1 356  SER n 
1 357  GLU n 
1 358  GLY n 
1 359  ASN n 
1 360  ALA n 
1 361  THR n 
1 362  SER n 
1 363  GLU n 
1 364  GLN n 
1 365  LEU n 
1 366  VAL n 
1 367  PRO n 
1 368  ALA n 
1 369  GLY n 
1 370  ARG n 
1 371  GLY n 
1 372  SER n 
1 373  TYR n 
1 374  ILE n 
1 375  PHE n 
1 376  SER n 
1 377  GLN n 
1 378  LEU n 
1 379  GLN n 
1 380  ALA n 
1 381  GLY n 
1 382  THR n 
1 383  ASN n 
1 384  TYR n 
1 385  THR n 
1 386  LEU n 
1 387  ALA n 
1 388  LEU n 
1 389  SER n 
1 390  MET n 
1 391  ILE n 
1 392  ASN n 
1 393  LYS n 
1 394  GLN n 
1 395  GLY n 
1 396  GLU n 
1 397  GLY n 
1 398  PRO n 
1 399  VAL n 
1 400  ALA n 
1 401  LYS n 
1 402  GLY n 
1 403  PHE n 
1 404  VAL n 
1 405  GLN n 
1 406  THR n 
1 407  HIS n 
1 408  SER n 
1 409  ALA n 
1 410  ARG n 
1 411  ASN n 
1 412  GLU n 
1 413  LYS n 
1 414  PRO n 
1 415  ALA n 
1 416  LYS n 
1 417  ASP n 
1 418  LEU n 
1 419  THR n 
1 420  GLU n 
1 421  SER n 
1 422  VAL n 
1 423  LEU n 
1 424  LEU n 
1 425  VAL n 
1 426  GLY n 
1 427  ARG n 
1 428  ARG n 
1 429  ALA n 
1 430  VAL n 
1 431  MET n 
1 432  TRP n 
1 433  GLN n 
1 434  SER n 
1 435  LEU n 
1 436  GLU n 
1 437  PRO n 
1 438  ALA n 
1 439  GLY n 
1 440  GLU n 
1 441  ASN n 
1 442  SER n 
1 443  MET n 
1 444  ILE n 
1 445  TYR n 
1 446  GLN n 
1 447  SER n 
1 448  GLN n 
1 449  GLU n 
1 450  GLU n 
1 451  LEU n 
1 452  ALA n 
1 453  ASP n 
1 454  ILE n 
1 455  ALA n 
1 456  TRP n 
1 457  SER n 
1 458  LYS n 
1 459  ARG n 
1 460  GLU n 
1 461  GLN n 
1 462  GLN n 
1 463  LEU n 
1 464  TRP n 
1 465  LEU n 
1 466  LEU n 
1 467  ASN n 
1 468  VAL n 
1 469  HIS n 
1 470  GLY n 
1 471  GLU n 
1 472  LEU n 
1 473  ARG n 
1 474  SER n 
1 475  LEU n 
1 476  LYS n 
1 477  PHE n 
1 478  GLU n 
1 479  SER n 
1 480  GLY n 
1 481  GLN n 
1 482  MET n 
1 483  VAL n 
1 484  SER n 
1 485  PRO n 
1 486  ALA n 
1 487  GLN n 
1 488  GLN n 
1 489  LEU n 
1 490  LYS n 
1 491  LEU n 
1 492  ASP n 
1 493  LEU n 
1 494  GLY n 
1 495  ASN n 
1 496  ILE n 
1 497  SER n 
1 498  SER n 
1 499  GLY n 
1 500  ARG n 
1 501  TRP n 
1 502  VAL n 
1 503  PRO n 
1 504  ARG n 
1 505  ARG n 
1 506  LEU n 
1 507  SER n 
1 508  PHE n 
1 509  ASP n 
1 510  TRP n 
1 511  LEU n 
1 512  HIS n 
1 513  HIS n 
1 514  ARG n 
1 515  LEU n 
1 516  TYR n 
1 517  PHE n 
1 518  ALA n 
1 519  MET n 
1 520  GLU n 
1 521  SER n 
1 522  PRO n 
1 523  GLU n 
1 524  ARG n 
1 525  ASN n 
1 526  GLN n 
1 527  SER n 
1 528  SER n 
1 529  PHE n 
1 530  GLN n 
1 531  ILE n 
1 532  ILE n 
1 533  SER n 
1 534  THR n 
1 535  ASP n 
1 536  LEU n 
1 537  LEU n 
1 538  GLY n 
1 539  GLU n 
1 540  SER n 
1 541  ALA n 
1 542  GLN n 
1 543  LYS n 
1 544  VAL n 
1 545  GLY n 
1 546  GLU n 
1 547  SER n 
1 548  PHE n 
1 549  ASP n 
1 550  LEU n 
1 551  PRO n 
1 552  VAL n 
1 553  GLU n 
1 554  GLN n 
1 555  LEU n 
1 556  GLU n 
1 557  VAL n 
1 558  ASP n 
1 559  ALA n 
1 560  LEU n 
1 561  ASN n 
1 562  GLY n 
1 563  TRP n 
1 564  ILE n 
1 565  PHE n 
1 566  TRP n 
1 567  ARG n 
1 568  ASN n 
1 569  GLU n 
1 570  GLU n 
1 571  SER n 
1 572  LEU n 
1 573  TRP n 
1 574  ARG n 
1 575  GLN n 
1 576  ASP n 
1 577  LEU n 
1 578  HIS n 
1 579  GLY n 
1 580  ARG n 
1 581  MET n 
1 582  ILE n 
1 583  HIS n 
1 584  ARG n 
1 585  LEU n 
1 586  LEU n 
1 587  ARG n 
1 588  ILE n 
1 589  ARG n 
1 590  GLN n 
1 591  PRO n 
1 592  GLY n 
1 593  TRP n 
1 594  PHE n 
1 595  LEU n 
1 596  VAL n 
1 597  GLN n 
1 598  PRO n 
1 599  GLN n 
1 600  HIS n 
1 601  PHE n 
1 602  ILE n 
1 603  ILE n 
1 604  HIS n 
1 605  LEU n 
1 606  MET n 
1 607  LEU n 
1 608  PRO n 
1 609  GLN n 
1 610  GLU n 
1 611  GLY n 
1 612  LYS n 
1 613  PHE n 
1 614  LEU n 
1 615  GLU n 
1 616  ILE n 
1 617  SER n 
1 618  TYR n 
1 619  ASP n 
1 620  GLY n 
1 621  GLY n 
1 622  PHE n 
1 623  LYS n 
1 624  HIS n 
1 625  PRO n 
1 626  LEU n 
1 627  PRO n 
1 628  LEU n 
1 629  PRO n 
1 630  PRO n 
1 631  PRO n 
1 632  SER n 
1 633  ASN n 
1 634  GLY n 
1 635  ALA n 
1 636  GLY n 
1 637  ASN n 
1 638  GLY n 
1 639  PRO n 
1 640  ALA n 
1 641  SER n 
1 642  SER n 
1 643  HIS n 
1 644  TRP n 
1 645  GLN n 
1 646  SER n 
1 647  PHE n 
1 648  ALA n 
1 649  LEU n 
1 650  LEU n 
1 651  GLY n 
1 652  ARG n 
1 653  SER n 
1 654  LEU n 
1 655  LEU n 
1 656  LEU n 
1 657  PRO n 
1 658  ASP n 
1 659  SER n 
1 660  GLY n 
1 661  GLN n 
1 662  LEU n 
1 663  ILE n 
1 664  LEU n 
1 665  VAL n 
1 666  GLU n 
1 667  GLN n 
1 668  GLN n 
1 669  GLY n 
1 670  GLN n 
1 671  ALA n 
1 672  ALA n 
1 673  SER n 
1 674  PRO n 
1 675  SER n 
1 676  ALA n 
1 677  SER n 
1 678  TRP n 
1 679  PRO n 
1 680  LEU n 
1 681  LYS n 
1 682  ASN n 
1 683  LEU n 
1 684  PRO n 
1 685  ASP n 
1 686  CYS n 
1 687  TRP n 
1 688  ALA n 
1 689  VAL n 
1 690  ILE n 
1 691  LEU n 
1 692  LEU n 
1 693  VAL n 
1 694  PRO n 
1 695  GLU n 
1 696  SER n 
1 697  GLN n 
1 698  PRO n 
1 699  LEU n 
1 700  THR n 
1 701  SER n 
1 702  ALA n 
1 703  GLY n 
1 704  GLY n 
1 705  LYS n 
1 706  PRO n 
1 707  HIS n 
1 708  SER n 
1 709  LEU n 
1 710  LYS n 
1 711  ALA n 
1 712  LEU n 
1 713  LEU n 
1 714  GLY n 
1 715  ALA n 
1 716  GLN n 
1 717  ALA n 
1 718  ALA n 
1 719  LYS n 
1 720  ILE n 
1 721  SER n 
1 722  TRP n 
1 723  LYS n 
1 724  GLU n 
1 725  PRO n 
1 726  GLU n 
1 727  ARG n 
1 728  ASN n 
1 729  PRO n 
1 730  TYR n 
1 731  GLN n 
1 732  SER n 
1 733  ALA n 
1 734  ASP n 
1 735  ALA n 
1 736  ALA n 
1 737  ARG n 
1 738  SER n 
1 739  TRP n 
1 740  SER n 
1 741  TYR n 
1 742  GLU n 
1 743  LEU n 
1 744  GLU n 
1 745  VAL n 
1 746  LEU n 
1 747  ASP n 
1 748  VAL n 
1 749  ALA n 
1 750  SER n 
1 751  GLN n 
1 752  SER n 
1 753  ALA n 
1 754  PHE n 
1 755  SER n 
1 756  ILE n 
1 757  ARG n 
1 758  ASN n 
1 759  ILE n 
1 760  ARG n 
1 761  GLY n 
1 762  PRO n 
1 763  ILE n 
1 764  PHE n 
1 765  GLY n 
1 766  LEU n 
1 767  GLN n 
1 768  ARG n 
1 769  LEU n 
1 770  GLN n 
1 771  PRO n 
1 772  ASP n 
1 773  ASN n 
1 774  LEU n 
1 775  TYR n 
1 776  GLN n 
1 777  LEU n 
1 778  ARG n 
1 779  VAL n 
1 780  ARG n 
1 781  ALA n 
1 782  ILE n 
1 783  ASN n 
1 784  VAL n 
1 785  ASP n 
1 786  GLY n 
1 787  GLU n 
1 788  PRO n 
1 789  GLY n 
1 790  GLU n 
1 791  TRP n 
1 792  THR n 
1 793  GLU n 
1 794  PRO n 
1 795  LEU n 
1 796  ALA n 
1 797  ALA n 
1 798  ARG n 
1 799  THR n 
1 800  TRP n 
1 801  PRO n 
1 802  LEU n 
1 803  GLY n 
1 804  PRO n 
1 805  HIS n 
1 806  ARG n 
1 807  LEU n 
1 808  ARG n 
1 809  TRP n 
1 810  ALA n 
1 811  SER n 
1 812  ARG n 
1 813  GLN n 
1 814  GLY n 
1 815  SER n 
1 816  VAL n 
1 817  ILE n 
1 818  HIS n 
1 819  THR n 
1 820  ASN n 
1 821  GLU n 
1 822  LEU n 
1 823  GLY n 
1 824  GLU n 
1 825  GLY n 
1 826  LEU n 
1 827  GLU n 
1 828  VAL n 
1 829  GLN n 
1 830  GLN n 
1 831  GLU n 
1 832  GLN n 
1 833  LEU n 
1 834  GLU n 
1 835  ARG n 
1 836  LEU n 
1 837  PRO n 
1 838  GLY n 
1 839  PRO n 
1 840  MET n 
1 841  THR n 
1 842  MET n 
1 843  VAL n 
1 844  ASN n 
1 845  GLU n 
1 846  SER n 
1 847  VAL n 
1 848  GLY n 
1 849  TYR n 
1 850  TYR n 
1 851  VAL n 
1 852  THR n 
1 853  GLY n 
1 854  ASP n 
1 855  GLY n 
1 856  LEU n 
1 857  LEU n 
1 858  HIS n 
1 859  CYS n 
1 860  ILE n 
1 861  ASN n 
1 862  LEU n 
1 863  VAL n 
1 864  HIS n 
1 865  SER n 
1 866  GLN n 
1 867  TRP n 
1 868  GLY n 
1 869  CYS n 
1 870  PRO n 
1 871  ILE n 
1 872  SER n 
1 873  GLU n 
1 874  PRO n 
1 875  LEU n 
1 876  GLN n 
1 877  HIS n 
1 878  VAL n 
1 879  GLY n 
1 880  SER n 
1 881  VAL n 
1 882  THR n 
1 883  TYR n 
1 884  ASP n 
1 885  TRP n 
1 886  ARG n 
1 887  GLY n 
1 888  GLY n 
1 889  ARG n 
1 890  VAL n 
1 891  TYR n 
1 892  TRP n 
1 893  THR n 
1 894  ASP n 
1 895  LEU n 
1 896  ALA n 
1 897  ARG n 
1 898  ASN n 
1 899  CYS n 
1 900  VAL n 
1 901  VAL n 
1 902  ARG n 
1 903  MET n 
1 904  ASP n 
1 905  PRO n 
1 906  TRP n 
1 907  SER n 
1 908  GLY n 
1 909  SER n 
1 910  ARG n 
1 911  GLU n 
1 912  LEU n 
1 913  LEU n 
1 914  PRO n 
1 915  VAL n 
1 916  PHE n 
1 917  GLU n 
1 918  ALA n 
1 919  ASN n 
1 920  PHE n 
1 921  LEU n 
1 922  ALA n 
1 923  LEU n 
1 924  ASP n 
1 925  PRO n 
1 926  ARG n 
1 927  GLN n 
1 928  GLY n 
1 929  HIS n 
1 930  LEU n 
1 931  TYR n 
1 932  TYR n 
1 933  ALA n 
1 934  THR n 
1 935  SER n 
1 936  SER n 
1 937  GLN n 
1 938  LEU n 
1 939  SER n 
1 940  ARG n 
1 941  HIS n 
1 942  GLY n 
1 943  SER n 
1 944  THR n 
1 945  PRO n 
1 946  ASP n 
1 947  GLU n 
1 948  ALA n 
1 949  VAL n 
1 950  THR n 
1 951  TYR n 
1 952  TYR n 
1 953  ARG n 
1 954  VAL n 
1 955  ASN n 
1 956  GLY n 
1 957  LEU n 
1 958  GLU n 
1 959  GLY n 
1 960  SER n 
1 961  ILE n 
1 962  ALA n 
1 963  SER n 
1 964  PHE n 
1 965  VAL n 
1 966  LEU n 
1 967  ASP n 
1 968  THR n 
1 969  GLN n 
1 970  GLN n 
1 971  ASP n 
1 972  GLN n 
1 973  LEU n 
1 974  PHE n 
1 975  TRP n 
1 976  LEU n 
1 977  VAL n 
1 978  LYS n 
1 979  GLY n 
1 980  SER n 
1 981  GLY n 
1 982  ALA n 
1 983  LEU n 
1 984  ARG n 
1 985  LEU n 
1 986  TYR n 
1 987  ARG n 
1 988  ALA n 
1 989  PRO n 
1 990  LEU n 
1 991  THR n 
1 992  ALA n 
1 993  GLY n 
1 994  GLY n 
1 995  ASP n 
1 996  SER n 
1 997  LEU n 
1 998  GLN n 
1 999  MET n 
1 1000 ILE n 
1 1001 GLN n 
1 1002 GLN n 
1 1003 ILE n 
1 1004 LYS n 
1 1005 GLY n 
1 1006 VAL n 
1 1007 PHE n 
1 1008 GLN n 
1 1009 ALA n 
1 1010 VAL n 
1 1011 PRO n 
1 1012 ASP n 
1 1013 SER n 
1 1014 LEU n 
1 1015 GLN n 
1 1016 LEU n 
1 1017 LEU n 
1 1018 ARG n 
1 1019 PRO n 
1 1020 LEU n 
1 1021 GLY n 
1 1022 ALA n 
1 1023 LEU n 
1 1024 LEU n 
1 1025 TRP n 
1 1026 LEU n 
1 1027 GLU n 
1 1028 ARG n 
1 1029 SER n 
1 1030 GLY n 
1 1031 ARG n 
1 1032 ARG n 
1 1033 ALA n 
1 1034 ARG n 
1 1035 LEU n 
1 1036 VAL n 
1 1037 ARG n 
1 1038 LEU n 
1 1039 ALA n 
1 1040 ALA n 
1 1041 PRO n 
1 1042 LEU n 
1 1043 ASP n 
1 1044 VAL n 
1 1045 MET n 
1 1046 GLU n 
1 1047 LEU n 
1 1048 PRO n 
1 1049 THR n 
1 1050 PRO n 
1 1051 ASP n 
1 1052 GLN n 
1 1053 ALA n 
1 1054 SER n 
1 1055 PRO n 
1 1056 ALA n 
1 1057 SER n 
1 1058 ALA n 
1 1059 LEU n 
1 1060 GLN n 
1 1061 LEU n 
1 1062 LEU n 
1 1063 ASP n 
1 1064 PRO n 
1 1065 GLN n 
1 1066 PRO n 
1 1067 LEU n 
1 1068 PRO n 
1 1069 PRO n 
1 1070 ARG n 
1 1071 ASP n 
1 1072 GLU n 
1 1073 GLY n 
1 1074 VAL n 
1 1075 ILE n 
1 1076 PRO n 
1 1077 MET n 
1 1078 THR n 
1 1079 VAL n 
1 1080 LEU n 
1 1081 PRO n 
1 1082 ASP n 
1 1083 SER n 
1 1084 VAL n 
1 1085 ARG n 
1 1086 LEU n 
1 1087 ASP n 
1 1088 ASP n 
1 1089 GLY n 
1 1090 HIS n 
1 1091 TRP n 
1 1092 ASP n 
1 1093 ASP n 
1 1094 PHE n 
1 1095 HIS n 
1 1096 VAL n 
1 1097 ARG n 
1 1098 TRP n 
1 1099 GLN n 
1 1100 PRO n 
1 1101 SER n 
1 1102 THR n 
1 1103 SER n 
1 1104 GLY n 
1 1105 GLY n 
1 1106 ASN n 
1 1107 HIS n 
1 1108 SER n 
1 1109 VAL n 
1 1110 SER n 
1 1111 TYR n 
1 1112 ARG n 
1 1113 LEU n 
1 1114 LEU n 
1 1115 LEU n 
1 1116 GLU n 
1 1117 PHE n 
1 1118 GLY n 
1 1119 GLN n 
1 1120 ARG n 
1 1121 LEU n 
1 1122 GLN n 
1 1123 THR n 
1 1124 LEU n 
1 1125 ASP n 
1 1126 LEU n 
1 1127 SER n 
1 1128 THR n 
1 1129 PRO n 
1 1130 PHE n 
1 1131 ALA n 
1 1132 ARG n 
1 1133 LEU n 
1 1134 THR n 
1 1135 GLN n 
1 1136 LEU n 
1 1137 PRO n 
1 1138 GLN n 
1 1139 ALA n 
1 1140 GLN n 
1 1141 LEU n 
1 1142 GLN n 
1 1143 LEU n 
1 1144 LYS n 
1 1145 ILE n 
1 1146 SER n 
1 1147 ILE n 
1 1148 THR n 
1 1149 PRO n 
1 1150 ARG n 
1 1151 THR n 
1 1152 ALA n 
1 1153 TRP n 
1 1154 ARG n 
1 1155 SER n 
1 1156 GLY n 
1 1157 ASP n 
1 1158 THR n 
1 1159 THR n 
1 1160 ARG n 
1 1161 VAL n 
1 1162 GLN n 
1 1163 LEU n 
1 1164 THR n 
1 1165 THR n 
1 1166 PRO n 
1 1167 PRO n 
1 1168 VAL n 
1 1169 ALA n 
1 1170 PRO n 
1 1171 SER n 
1 1172 GLN n 
1 1173 PRO n 
1 1174 ARG n 
1 1175 ARG n 
1 1176 LEU n 
1 1177 ARG n 
1 1178 VAL n 
1 1179 PHE n 
1 1180 VAL n 
1 1181 GLU n 
1 1182 ARG n 
1 1183 LEU n 
1 1184 ALA n 
1 1185 THR n 
1 1186 ALA n 
1 1187 LEU n 
1 1188 GLN n 
1 1189 GLU n 
1 1190 ALA n 
1 1191 ASN n 
1 1192 VAL n 
1 1193 SER n 
1 1194 ALA n 
1 1195 VAL n 
1 1196 LEU n 
1 1197 ARG n 
1 1198 TRP n 
1 1199 ASP n 
1 1200 ALA n 
1 1201 PRO n 
1 1202 GLU n 
1 1203 GLN n 
1 1204 GLY n 
1 1205 GLN n 
1 1206 GLU n 
1 1207 ALA n 
1 1208 PRO n 
1 1209 MET n 
1 1210 GLN n 
1 1211 ALA n 
1 1212 LEU n 
1 1213 GLU n 
1 1214 TYR n 
1 1215 HIS n 
1 1216 ILE n 
1 1217 SER n 
1 1218 CYS n 
1 1219 TRP n 
1 1220 VAL n 
1 1221 GLY n 
1 1222 SER n 
1 1223 GLU n 
1 1224 LEU n 
1 1225 HIS n 
1 1226 GLU n 
1 1227 GLU n 
1 1228 LEU n 
1 1229 ARG n 
1 1230 LEU n 
1 1231 ASN n 
1 1232 GLN n 
1 1233 SER n 
1 1234 ALA n 
1 1235 LEU n 
1 1236 GLU n 
1 1237 ALA n 
1 1238 ARG n 
1 1239 VAL n 
1 1240 GLU n 
1 1241 HIS n 
1 1242 LEU n 
1 1243 GLN n 
1 1244 PRO n 
1 1245 ASP n 
1 1246 GLN n 
1 1247 THR n 
1 1248 TYR n 
1 1249 HIS n 
1 1250 PHE n 
1 1251 GLN n 
1 1252 VAL n 
1 1253 GLU n 
1 1254 ALA n 
1 1255 ARG n 
1 1256 VAL n 
1 1257 ALA n 
1 1258 ALA n 
1 1259 THR n 
1 1260 GLY n 
1 1261 ALA n 
1 1262 ALA n 
1 1263 ALA n 
1 1264 GLY n 
1 1265 ALA n 
1 1266 ALA n 
1 1267 SER n 
1 1268 HIS n 
1 1269 ALA n 
1 1270 LEU n 
1 1271 HIS n 
1 1272 VAL n 
1 1273 ALA n 
1 1274 PRO n 
1 1275 GLU n 
1 1276 VAL n 
1 1277 GLN n 
1 1278 ALA n 
1 1279 VAL n 
1 1280 PRO n 
1 1281 ARG n 
1 1282 VAL n 
1 1283 LEU n 
1 1284 TYR n 
1 1285 ALA n 
1 1286 ASN n 
1 1287 ALA n 
1 1288 GLU n 
1 1289 PHE n 
1 1290 ILE n 
1 1291 GLY n 
1 1292 GLU n 
1 1293 LEU n 
1 1294 ASP n 
1 1295 LEU n 
1 1296 ASP n 
1 1297 THR n 
1 1298 ARG n 
1 1299 ASN n 
1 1300 ARG n 
1 1301 ARG n 
1 1302 ARG n 
1 1303 LEU n 
1 1304 VAL n 
1 1305 HIS n 
1 1306 THR n 
1 1307 ALA n 
1 1308 SER n 
1 1309 PRO n 
1 1310 VAL n 
1 1311 GLU n 
1 1312 HIS n 
1 1313 LEU n 
1 1314 VAL n 
1 1315 GLY n 
1 1316 ILE n 
1 1317 GLU n 
1 1318 GLY n 
1 1319 GLU n 
1 1320 GLN n 
1 1321 ARG n 
1 1322 LEU n 
1 1323 LEU n 
1 1324 TRP n 
1 1325 VAL n 
1 1326 ASN n 
1 1327 GLU n 
1 1328 HIS n 
1 1329 VAL n 
1 1330 GLU n 
1 1331 LEU n 
1 1332 LEU n 
1 1333 THR n 
1 1334 HIS n 
1 1335 VAL n 
1 1336 PRO n 
1 1337 GLY n 
1 1338 SER n 
1 1339 ALA n 
1 1340 PRO n 
1 1341 ALA n 
1 1342 LYS n 
1 1343 LEU n 
1 1344 ALA n 
1 1345 ARG n 
1 1346 MET n 
1 1347 ARG n 
1 1348 ALA n 
1 1349 GLU n 
1 1350 VAL n 
1 1351 LEU n 
1 1352 ALA n 
1 1353 LEU n 
1 1354 ALA n 
1 1355 VAL n 
1 1356 ASP n 
1 1357 TRP n 
1 1358 ILE n 
1 1359 GLN n 
1 1360 ARG n 
1 1361 ILE n 
1 1362 VAL n 
1 1363 TYR n 
1 1364 TRP n 
1 1365 ALA n 
1 1366 GLU n 
1 1367 LEU n 
1 1368 ASP n 
1 1369 ALA n 
1 1370 THR n 
1 1371 ALA n 
1 1372 PRO n 
1 1373 GLN n 
1 1374 ALA n 
1 1375 ALA n 
1 1376 ILE n 
1 1377 ILE n 
1 1378 TYR n 
1 1379 ARG n 
1 1380 LEU n 
1 1381 ASP n 
1 1382 LEU n 
1 1383 CYS n 
1 1384 ASN n 
1 1385 PHE n 
1 1386 GLU n 
1 1387 GLY n 
1 1388 LYS n 
1 1389 ILE n 
1 1390 LEU n 
1 1391 GLN n 
1 1392 GLY n 
1 1393 GLU n 
1 1394 ARG n 
1 1395 VAL n 
1 1396 TRP n 
1 1397 SER n 
1 1398 THR n 
1 1399 PRO n 
1 1400 ARG n 
1 1401 GLY n 
1 1402 ARG n 
1 1403 LEU n 
1 1404 LEU n 
1 1405 LYS n 
1 1406 ASP n 
1 1407 LEU n 
1 1408 VAL n 
1 1409 ALA n 
1 1410 LEU n 
1 1411 PRO n 
1 1412 GLN n 
1 1413 ALA n 
1 1414 GLN n 
1 1415 SER n 
1 1416 LEU n 
1 1417 ILE n 
1 1418 TRP n 
1 1419 LEU n 
1 1420 GLU n 
1 1421 TYR n 
1 1422 GLU n 
1 1423 GLN n 
1 1424 GLY n 
1 1425 SER n 
1 1426 PRO n 
1 1427 ARG n 
1 1428 ASN n 
1 1429 GLY n 
1 1430 SER n 
1 1431 LEU n 
1 1432 ARG n 
1 1433 GLY n 
1 1434 ARG n 
1 1435 ASN n 
1 1436 LEU n 
1 1437 THR n 
1 1438 ASP n 
1 1439 GLY n 
1 1440 SER n 
1 1441 GLU n 
1 1442 LEU n 
1 1443 GLU n 
1 1444 TRP n 
1 1445 ALA n 
1 1446 THR n 
1 1447 VAL n 
1 1448 GLN n 
1 1449 PRO n 
1 1450 LEU n 
1 1451 ILE n 
1 1452 ARG n 
1 1453 LEU n 
1 1454 HIS n 
1 1455 ALA n 
1 1456 GLY n 
1 1457 SER n 
1 1458 LEU n 
1 1459 GLU n 
1 1460 PRO n 
1 1461 GLY n 
1 1462 SER n 
1 1463 GLU n 
1 1464 THR n 
1 1465 LEU n 
1 1466 ASN n 
1 1467 LEU n 
1 1468 VAL n 
1 1469 ASP n 
1 1470 ASN n 
1 1471 GLN n 
1 1472 GLY n 
1 1473 LYS n 
1 1474 LEU n 
1 1475 CYS n 
1 1476 VAL n 
1 1477 TYR n 
1 1478 ASP n 
1 1479 VAL n 
1 1480 ALA n 
1 1481 ARG n 
1 1482 GLN n 
1 1483 LEU n 
1 1484 CYS n 
1 1485 THR n 
1 1486 ALA n 
1 1487 SER n 
1 1488 ALA n 
1 1489 LEU n 
1 1490 ARG n 
1 1491 ALA n 
1 1492 GLN n 
1 1493 LEU n 
1 1494 ASN n 
1 1495 LEU n 
1 1496 LEU n 
1 1497 GLY n 
1 1498 GLU n 
1 1499 ASP n 
1 1500 SER n 
1 1501 ILE n 
1 1502 ALA n 
1 1503 GLY n 
1 1504 GLN n 
1 1505 LEU n 
1 1506 ALA n 
1 1507 GLN n 
1 1508 ASP n 
1 1509 SER n 
1 1510 GLY n 
1 1511 TYR n 
1 1512 LEU n 
1 1513 TYR n 
1 1514 ALA n 
1 1515 VAL n 
1 1516 LYS n 
1 1517 ASN n 
1 1518 TRP n 
1 1519 SER n 
1 1520 ILE n 
1 1521 ARG n 
1 1522 ALA n 
1 1523 TYR n 
1 1524 GLY n 
1 1525 ARG n 
1 1526 ARG n 
1 1527 ARG n 
1 1528 GLN n 
1 1529 GLN n 
1 1530 LEU n 
1 1531 GLU n 
1 1532 TYR n 
1 1533 THR n 
1 1534 VAL n 
1 1535 GLU n 
1 1536 LEU n 
1 1537 GLU n 
1 1538 PRO n 
1 1539 GLU n 
1 1540 GLU n 
1 1541 VAL n 
1 1542 ARG n 
1 1543 LEU n 
1 1544 LEU n 
1 1545 GLN n 
1 1546 ALA n 
1 1547 HIS n 
1 1548 ASN n 
1 1549 TYR n 
1 1550 GLN n 
1 1551 ALA n 
1 1552 TYR n 
1 1553 PRO n 
1 1554 PRO n 
1 1555 LYS n 
1 1556 ASN n 
1 1557 CYS n 
1 1558 LEU n 
1 1559 LEU n 
1 1560 LEU n 
1 1561 PRO n 
1 1562 SER n 
1 1563 SER n 
1 1564 GLY n 
1 1565 GLY n 
1 1566 SER n 
1 1567 LEU n 
1 1568 LEU n 
1 1569 LYS n 
1 1570 ALA n 
1 1571 THR n 
1 1572 ASP n 
1 1573 CYS n 
1 1574 GLU n 
1 1575 GLU n 
1 1576 GLN n 
1 1577 ARG n 
1 1578 CYS n 
1 1579 LEU n 
1 1580 LEU n 
1 1581 ASN n 
1 1582 LEU n 
1 1583 PRO n 
1 1584 MET n 
1 1585 ILE n 
1 1586 THR n 
1 1587 ALA n 
1 1588 SER n 
1 1589 GLU n 
1 1590 ASP n 
1 1591 CYS n 
1 1592 PRO n 
1 1593 LEU n 
1 1594 PRO n 
1 1595 ILE n 
1 1596 PRO n 
1 1597 GLY n 
1 1598 VAL n 
1 1599 ARG n 
1 1600 TYR n 
1 1601 GLN n 
1 1602 LEU n 
1 1603 ASN n 
1 1604 LEU n 
1 1605 THR n 
1 1606 LEU n 
1 1607 ALA n 
1 1608 ARG n 
1 1609 GLY n 
1 1610 PRO n 
1 1611 GLY n 
1 1612 SER n 
1 1613 GLU n 
1 1614 GLU n 
1 1615 HIS n 
1 1616 ASP n 
1 1617 HIS n 
1 1618 GLY n 
1 1619 VAL n 
1 1620 GLU n 
1 1621 PRO n 
1 1622 LEU n 
1 1623 GLY n 
1 1624 GLN n 
1 1625 TRP n 
1 1626 LEU n 
1 1627 LEU n 
1 1628 GLY n 
1 1629 ALA n 
1 1630 GLY n 
1 1631 GLU n 
1 1632 SER n 
1 1633 LEU n 
1 1634 ASN n 
1 1635 LEU n 
1 1636 THR n 
1 1637 ASP n 
1 1638 LEU n 
1 1639 LEU n 
1 1640 PRO n 
1 1641 PHE n 
1 1642 THR n 
1 1643 ARG n 
1 1644 TYR n 
1 1645 ARG n 
1 1646 VAL n 
1 1647 SER n 
1 1648 GLY n 
1 1649 ILE n 
1 1650 LEU n 
1 1651 SER n 
1 1652 SER n 
1 1653 PHE n 
1 1654 TYR n 
1 1655 GLN n 
1 1656 LYS n 
1 1657 LYS n 
1 1658 LEU n 
1 1659 ALA n 
1 1660 LEU n 
1 1661 PRO n 
1 1662 THR n 
1 1663 LEU n 
1 1664 VAL n 
1 1665 LEU n 
1 1666 ALA n 
1 1667 PRO n 
1 1668 LEU n 
1 1669 GLU n 
1 1670 LEU n 
1 1671 LEU n 
1 1672 THR n 
1 1673 ALA n 
1 1674 SER n 
1 1675 ALA n 
1 1676 THR n 
1 1677 PRO n 
1 1678 SER n 
1 1679 PRO n 
1 1680 PRO n 
1 1681 ARG n 
1 1682 ASN n 
1 1683 PHE n 
1 1684 SER n 
1 1685 VAL n 
1 1686 ARG n 
1 1687 VAL n 
1 1688 LEU n 
1 1689 SER n 
1 1690 PRO n 
1 1691 ARG n 
1 1692 GLU n 
1 1693 LEU n 
1 1694 GLU n 
1 1695 VAL n 
1 1696 SER n 
1 1697 TRP n 
1 1698 LEU n 
1 1699 PRO n 
1 1700 PRO n 
1 1701 GLU n 
1 1702 GLN n 
1 1703 LEU n 
1 1704 ARG n 
1 1705 SER n 
1 1706 GLU n 
1 1707 SER n 
1 1708 VAL n 
1 1709 TYR n 
1 1710 TYR n 
1 1711 THR n 
1 1712 LEU n 
1 1713 HIS n 
1 1714 TRP n 
1 1715 GLN n 
1 1716 GLN n 
1 1717 GLU n 
1 1718 LEU n 
1 1719 ASP n 
1 1720 GLY n 
1 1721 GLU n 
1 1722 ASN n 
1 1723 VAL n 
1 1724 GLN n 
1 1725 ASP n 
1 1726 ARG n 
1 1727 ARG n 
1 1728 GLU n 
1 1729 TRP n 
1 1730 GLU n 
1 1731 ALA n 
1 1732 HIS n 
1 1733 GLU n 
1 1734 ARG n 
1 1735 ARG n 
1 1736 LEU n 
1 1737 GLU n 
1 1738 THR n 
1 1739 ALA n 
1 1740 GLY n 
1 1741 THR n 
1 1742 HIS n 
1 1743 ARG n 
1 1744 LEU n 
1 1745 THR n 
1 1746 GLY n 
1 1747 ILE n 
1 1748 LYS n 
1 1749 PRO n 
1 1750 GLY n 
1 1751 SER n 
1 1752 GLY n 
1 1753 TYR n 
1 1754 SER n 
1 1755 LEU n 
1 1756 TRP n 
1 1757 VAL n 
1 1758 GLN n 
1 1759 ALA n 
1 1760 HIS n 
1 1761 ALA n 
1 1762 THR n 
1 1763 PRO n 
1 1764 THR n 
1 1765 LYS n 
1 1766 SER n 
1 1767 ASN n 
1 1768 SER n 
1 1769 SER n 
1 1770 GLU n 
1 1771 ARG n 
1 1772 LEU n 
1 1773 HIS n 
1 1774 VAL n 
1 1775 ARG n 
1 1776 SER n 
1 1777 PHE n 
1 1778 ALA n 
1 1779 GLU n 
1 1780 LEU n 
1 1781 PRO n 
1 1782 GLU n 
1 1783 LEU n 
1 1784 GLN n 
1 1785 LEU n 
1 1786 LEU n 
1 1787 GLU n 
1 1788 LEU n 
1 1789 GLY n 
1 1790 PRO n 
1 1791 TYR n 
1 1792 SER n 
1 1793 LEU n 
1 1794 SER n 
1 1795 LEU n 
1 1796 THR n 
1 1797 TRP n 
1 1798 ALA n 
1 1799 GLY n 
1 1800 THR n 
1 1801 PRO n 
1 1802 ASP n 
1 1803 PRO n 
1 1804 LEU n 
1 1805 GLY n 
1 1806 SER n 
1 1807 LEU n 
1 1808 GLN n 
1 1809 LEU n 
1 1810 GLU n 
1 1811 CYS n 
1 1812 ARG n 
1 1813 SER n 
1 1814 SER n 
1 1815 ALA n 
1 1816 GLU n 
1 1817 GLN n 
1 1818 LEU n 
1 1819 ARG n 
1 1820 ARG n 
1 1821 ASN n 
1 1822 VAL n 
1 1823 ALA n 
1 1824 GLY n 
1 1825 ASN n 
1 1826 HIS n 
1 1827 THR n 
1 1828 LYS n 
1 1829 MET n 
1 1830 VAL n 
1 1831 VAL n 
1 1832 GLU n 
1 1833 PRO n 
1 1834 LEU n 
1 1835 GLN n 
1 1836 PRO n 
1 1837 ARG n 
1 1838 THR n 
1 1839 ARG n 
1 1840 TYR n 
1 1841 GLN n 
1 1842 CYS n 
1 1843 ARG n 
1 1844 LEU n 
1 1845 LEU n 
1 1846 LEU n 
1 1847 GLY n 
1 1848 TYR n 
1 1849 ALA n 
1 1850 ALA n 
1 1851 THR n 
1 1852 PRO n 
1 1853 GLY n 
1 1854 ALA n 
1 1855 PRO n 
1 1856 LEU n 
1 1857 TYR n 
1 1858 HIS n 
1 1859 GLY n 
1 1860 THR n 
1 1861 ALA n 
1 1862 GLU n 
1 1863 VAL n 
1 1864 TYR n 
1 1865 GLU n 
1 1866 THR n 
1 1867 LEU n 
1 1868 GLY n 
1 1869 ASP n 
1 1870 ALA n 
1 1871 PRO n 
1 1872 SER n 
1 1873 GLN n 
1 1874 PRO n 
1 1875 GLY n 
1 1876 LYS n 
1 1877 PRO n 
1 1878 GLN n 
1 1879 LEU n 
1 1880 GLU n 
1 1881 HIS n 
1 1882 ILE n 
1 1883 ALA n 
1 1884 GLU n 
1 1885 GLU n 
1 1886 VAL n 
1 1887 PHE n 
1 1888 ARG n 
1 1889 VAL n 
1 1890 THR n 
1 1891 TRP n 
1 1892 THR n 
1 1893 ALA n 
1 1894 ALA n 
1 1895 ARG n 
1 1896 GLY n 
1 1897 ASN n 
1 1898 GLY n 
1 1899 ALA n 
1 1900 PRO n 
1 1901 ILE n 
1 1902 ALA n 
1 1903 LEU n 
1 1904 TYR n 
1 1905 ASN n 
1 1906 LEU n 
1 1907 GLU n 
1 1908 ALA n 
1 1909 LEU n 
1 1910 GLN n 
1 1911 ALA n 
1 1912 ARG n 
1 1913 SER n 
1 1914 ASP n 
1 1915 ILE n 
1 1916 ASN n 
1 1917 SER n 
1 1918 GLY n 
1 1919 GLY n 
1 1920 SER n 
1 1921 LEU n 
1 1922 GLU n 
1 1923 GLN n 
1 1924 LEU n 
1 1925 PRO n 
1 1926 TRP n 
1 1927 ALA n 
1 1928 GLU n 
1 1929 GLU n 
1 1930 PRO n 
1 1931 VAL n 
1 1932 VAL n 
1 1933 VAL n 
1 1934 GLU n 
1 1935 ASP n 
1 1936 GLN n 
1 1937 TRP n 
1 1938 LEU n 
1 1939 ASP n 
1 1940 PHE n 
1 1941 CYS n 
1 1942 ASN n 
1 1943 THR n 
1 1944 THR n 
1 1945 GLU n 
1 1946 LEU n 
1 1947 SER n 
1 1948 CYS n 
1 1949 ILE n 
1 1950 VAL n 
1 1951 LYS n 
1 1952 SER n 
1 1953 LEU n 
1 1954 HIS n 
1 1955 SER n 
1 1956 SER n 
1 1957 ARG n 
1 1958 LEU n 
1 1959 LEU n 
1 1960 LEU n 
1 1961 PHE n 
1 1962 ARG n 
1 1963 VAL n 
1 1964 ARG n 
1 1965 ALA n 
1 1966 ARG n 
1 1967 SER n 
1 1968 LEU n 
1 1969 GLU n 
1 1970 HIS n 
1 1971 GLY n 
1 1972 TRP n 
1 1973 GLY n 
1 1974 PRO n 
1 1975 TYR n 
1 1976 SER n 
1 1977 GLU n 
1 1978 GLU n 
1 1979 SER n 
1 1980 GLU n 
1 1981 ARG n 
1 1982 VAL n 
1 1983 ALA n 
1 1984 GLU n 
1 1985 PRO n 
1 1986 PHE n 
1 1987 VAL n 
1 1988 SER n 
1 1989 HIS n 
1 1990 HIS n 
1 1991 HIS n 
1 1992 HIS n 
1 1993 HIS n 
1 1994 HIS n 
1 1995 TRP n 
1 1996 SER n 
1 1997 HIS n 
1 1998 PRO n 
1 1999 GLN n 
1 2000 PHE n 
1 2001 GLU n 
1 2002 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   2002 
_entity_src_gen.gene_src_common_name               'fruit fly' 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'sev, HD-265, CG18085' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Drosophila melanogaster' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     7227 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               'fruit fly' 
_entity_src_gen.pdbx_host_org_scientific_name      'Drosophila melanogaster' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     7227 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DGlcpNAcb1-4DGlcpNAcb1-ROH                            'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/1,2,1/[a2122h-1b_1-5_2*NCC/3=O]/1-1/a4-b1' WURCS                       PDB2Glycan 1.1.0 
3 2 '[][D-1-deoxy-GlcpNAc]{[(4+1)][b-D-GlcpNAc]{}}'       LINUCS                      PDB-CARE   ?     
# 
_pdbx_entity_branch_link.link_id                    1 
_pdbx_entity_branch_link.entity_id                  2 
_pdbx_entity_branch_link.entity_branch_list_num_1   2 
_pdbx_entity_branch_link.comp_id_1                  NAG 
_pdbx_entity_branch_link.atom_id_1                  C1 
_pdbx_entity_branch_link.leaving_atom_id_1          O1 
_pdbx_entity_branch_link.entity_branch_list_num_2   1 
_pdbx_entity_branch_link.comp_id_2                  NAG 
_pdbx_entity_branch_link.atom_id_2                  O4 
_pdbx_entity_branch_link.leaving_atom_id_2          HO4 
_pdbx_entity_branch_link.value_order                sing 
_pdbx_entity_branch_link.details                    ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE                                  ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE                                 ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE                               ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'                          ? 'C4 H7 N O4'     133.103 
CYS 'L-peptide linking'          y CYSTEINE                                 ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE                                ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'                          ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE                                  ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE                                ? 'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE                               ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE                                  ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE                                   ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE                               ? 'C5 H11 N O2 S'  149.211 
NAG 'D-saccharide, beta linking' . 2-acetamido-2-deoxy-beta-D-glucopyranose 
;N-acetyl-beta-D-glucosamine; 2-acetamido-2-deoxy-beta-D-glucose; 2-acetamido-2-deoxy-D-glucose; 2-acetamido-2-deoxy-glucose; N-ACETYL-D-GLUCOSAMINE
;
'C8 H15 N O6'    221.208 
PHE 'L-peptide linking'          y PHENYLALANINE                            ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE                                  ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE                                   ? 'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE                                ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN                               ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE                                 ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE                                   ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
NAG 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpNAcb                      
NAG 'COMMON NAME'                         GMML     1.0 N-acetyl-b-D-glucopyranosamine 
NAG 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-GlcpNAc                    
NAG 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 GlcNAc                         
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    ASP 1    123  ?    ?   ?   A . n 
A 1 2    VAL 2    124  ?    ?   ?   A . n 
A 1 3    CYS 3    125  ?    ?   ?   A . n 
A 1 4    ARG 4    126  ?    ?   ?   A . n 
A 1 5    SER 5    127  ?    ?   ?   A . n 
A 1 6    HIS 6    128  ?    ?   ?   A . n 
A 1 7    ASN 7    129  ?    ?   ?   A . n 
A 1 8    TYR 8    130  ?    ?   ?   A . n 
A 1 9    THR 9    131  ?    ?   ?   A . n 
A 1 10   VAL 10   132  ?    ?   ?   A . n 
A 1 11   HIS 11   133  ?    ?   ?   A . n 
A 1 12   GLN 12   134  ?    ?   ?   A . n 
A 1 13   SER 13   135  ?    ?   ?   A . n 
A 1 14   PRO 14   136  ?    ?   ?   A . n 
A 1 15   GLU 15   137  ?    ?   ?   A . n 
A 1 16   PRO 16   138  ?    ?   ?   A . n 
A 1 17   VAL 17   139  ?    ?   ?   A . n 
A 1 18   SER 18   140  ?    ?   ?   A . n 
A 1 19   LYS 19   141  ?    ?   ?   A . n 
A 1 20   ASP 20   142  ?    ?   ?   A . n 
A 1 21   GLN 21   143  ?    ?   ?   A . n 
A 1 22   MET 22   144  ?    ?   ?   A . n 
A 1 23   ARG 23   145  ?    ?   ?   A . n 
A 1 24   LEU 24   146  ?    ?   ?   A . n 
A 1 25   LEU 25   147  ?    ?   ?   A . n 
A 1 26   ARG 26   148  ?    ?   ?   A . n 
A 1 27   PRO 27   149  ?    ?   ?   A . n 
A 1 28   LYS 28   150  ?    ?   ?   A . n 
A 1 29   LEU 29   151  ?    ?   ?   A . n 
A 1 30   ASP 30   152  ?    ?   ?   A . n 
A 1 31   SER 31   153  ?    ?   ?   A . n 
A 1 32   ASP 32   154  ?    ?   ?   A . n 
A 1 33   VAL 33   155  ?    ?   ?   A . n 
A 1 34   VAL 34   156  ?    ?   ?   A . n 
A 1 35   GLU 35   157  ?    ?   ?   A . n 
A 1 36   LYS 36   158  ?    ?   ?   A . n 
A 1 37   VAL 37   159  ?    ?   ?   A . n 
A 1 38   ALA 38   160  ?    ?   ?   A . n 
A 1 39   ILE 39   161  ?    ?   ?   A . n 
A 1 40   TRP 40   162  ?    ?   ?   A . n 
A 1 41   HIS 41   163  ?    ?   ?   A . n 
A 1 42   LYS 42   164  ?    ?   ?   A . n 
A 1 43   HIS 43   165  ?    ?   ?   A . n 
A 1 44   ALA 44   166  ?    ?   ?   A . n 
A 1 45   ALA 45   167  ?    ?   ?   A . n 
A 1 46   ALA 46   168  ?    ?   ?   A . n 
A 1 47   ALA 47   169  ?    ?   ?   A . n 
A 1 48   PRO 48   170  ?    ?   ?   A . n 
A 1 49   PRO 49   171  ?    ?   ?   A . n 
A 1 50   SER 50   172  ?    ?   ?   A . n 
A 1 51   ILE 51   173  ?    ?   ?   A . n 
A 1 52   VAL 52   174  ?    ?   ?   A . n 
A 1 53   GLU 53   175  ?    ?   ?   A . n 
A 1 54   GLY 54   176  ?    ?   ?   A . n 
A 1 55   ILE 55   177  ?    ?   ?   A . n 
A 1 56   ALA 56   178  ?    ?   ?   A . n 
A 1 57   ILE 57   179  ?    ?   ?   A . n 
A 1 58   SER 58   180  ?    ?   ?   A . n 
A 1 59   SER 59   181  ?    ?   ?   A . n 
A 1 60   ARG 60   182  ?    ?   ?   A . n 
A 1 61   PRO 61   183  ?    ?   ?   A . n 
A 1 62   GLN 62   184  ?    ?   ?   A . n 
A 1 63   SER 63   185  ?    ?   ?   A . n 
A 1 64   THR 64   186  ?    ?   ?   A . n 
A 1 65   MET 65   187  ?    ?   ?   A . n 
A 1 66   ALA 66   188  ?    ?   ?   A . n 
A 1 67   HIS 67   189  ?    ?   ?   A . n 
A 1 68   HIS 68   190  ?    ?   ?   A . n 
A 1 69   PRO 69   191  ?    ?   ?   A . n 
A 1 70   ASP 70   192  ?    ?   ?   A . n 
A 1 71   ASP 71   193  ?    ?   ?   A . n 
A 1 72   ARG 72   194  ?    ?   ?   A . n 
A 1 73   ASP 73   195  ?    ?   ?   A . n 
A 1 74   ARG 74   196  ?    ?   ?   A . n 
A 1 75   ASP 75   197  ?    ?   ?   A . n 
A 1 76   ARG 76   198  ?    ?   ?   A . n 
A 1 77   ASP 77   199  ?    ?   ?   A . n 
A 1 78   PRO 78   200  ?    ?   ?   A . n 
A 1 79   SER 79   201  ?    ?   ?   A . n 
A 1 80   GLU 80   202  ?    ?   ?   A . n 
A 1 81   GLU 81   203  ?    ?   ?   A . n 
A 1 82   GLN 82   204  ?    ?   ?   A . n 
A 1 83   HIS 83   205  ?    ?   ?   A . n 
A 1 84   GLY 84   206  206  GLY GLY A . n 
A 1 85   VAL 85   207  207  VAL VAL A . n 
A 1 86   ASP 86   208  208  ASP ASP A . n 
A 1 87   GLU 87   209  209  GLU GLU A . n 
A 1 88   ARG 88   210  210  ARG ARG A . n 
A 1 89   MET 89   211  211  MET MET A . n 
A 1 90   VAL 90   212  212  VAL VAL A . n 
A 1 91   LEU 91   213  213  LEU LEU A . n 
A 1 92   GLU 92   214  214  GLU GLU A . n 
A 1 93   ARG 93   215  215  ARG ARG A . n 
A 1 94   VAL 94   216  216  VAL VAL A . n 
A 1 95   THR 95   217  217  THR THR A . n 
A 1 96   ARG 96   218  218  ARG ARG A . n 
A 1 97   ASP 97   219  219  ASP ASP A . n 
A 1 98   CYS 98   220  220  CYS CYS A . n 
A 1 99   VAL 99   221  221  VAL VAL A . n 
A 1 100  GLN 100  222  222  GLN GLN A . n 
A 1 101  ARG 101  223  223  ARG ARG A . n 
A 1 102  CYS 102  224  224  CYS CYS A . n 
A 1 103  ILE 103  225  225  ILE ILE A . n 
A 1 104  VAL 104  226  226  VAL VAL A . n 
A 1 105  GLU 105  227  227  GLU GLU A . n 
A 1 106  GLU 106  228  228  GLU GLU A . n 
A 1 107  ASP 107  229  229  ASP ASP A . n 
A 1 108  LEU 108  230  230  LEU LEU A . n 
A 1 109  PHE 109  231  231  PHE PHE A . n 
A 1 110  LEU 110  232  232  LEU LEU A . n 
A 1 111  ASP 111  233  233  ASP ASP A . n 
A 1 112  GLU 112  234  234  GLU GLU A . n 
A 1 113  PHE 113  235  235  PHE PHE A . n 
A 1 114  GLY 114  236  236  GLY GLY A . n 
A 1 115  ILE 115  237  237  ILE ILE A . n 
A 1 116  GLN 116  238  238  GLN GLN A . n 
A 1 117  CYS 117  239  239  CYS CYS A . n 
A 1 118  GLU 118  240  240  GLU GLU A . n 
A 1 119  LYS 119  241  241  LYS LYS A . n 
A 1 120  ALA 120  242  242  ALA ALA A . n 
A 1 121  ASP 121  243  243  ASP ASP A . n 
A 1 122  ASN 122  244  244  ASN ASN A . n 
A 1 123  GLY 123  245  245  GLY GLY A . n 
A 1 124  GLU 124  246  246  GLU GLU A . n 
A 1 125  LYS 125  247  247  LYS LYS A . n 
A 1 126  CYS 126  248  248  CYS CYS A . n 
A 1 127  TYR 127  249  249  TYR TYR A . n 
A 1 128  LYS 128  250  250  LYS LYS A . n 
A 1 129  THR 129  251  251  THR THR A . n 
A 1 130  ARG 130  252  252  ARG ARG A . n 
A 1 131  CYS 131  253  253  CYS CYS A . n 
A 1 132  THR 132  254  254  THR THR A . n 
A 1 133  LYS 133  255  255  LYS LYS A . n 
A 1 134  GLY 134  256  256  GLY GLY A . n 
A 1 135  CYS 135  257  257  CYS CYS A . n 
A 1 136  ALA 136  258  258  ALA ALA A . n 
A 1 137  GLN 137  259  259  GLN GLN A . n 
A 1 138  TRP 138  260  260  TRP TRP A . n 
A 1 139  TYR 139  261  261  TYR TYR A . n 
A 1 140  ARG 140  262  262  ARG ARG A . n 
A 1 141  ALA 141  263  263  ALA ALA A . n 
A 1 142  LEU 142  264  264  LEU LEU A . n 
A 1 143  LYS 143  265  265  LYS LYS A . n 
A 1 144  GLU 144  266  266  GLU GLU A . n 
A 1 145  LEU 145  267  267  LEU LEU A . n 
A 1 146  GLU 146  268  268  GLU GLU A . n 
A 1 147  SER 147  269  269  SER SER A . n 
A 1 148  CYS 148  270  270  CYS CYS A . n 
A 1 149  GLN 149  271  271  GLN GLN A . n 
A 1 150  GLU 150  272  272  GLU GLU A . n 
A 1 151  ALA 151  273  273  ALA ALA A . n 
A 1 152  CYS 152  274  274  CYS CYS A . n 
A 1 153  LEU 153  275  275  LEU LEU A . n 
A 1 154  SER 154  276  276  SER SER A . n 
A 1 155  LEU 155  277  277  LEU LEU A . n 
A 1 156  GLN 156  278  278  GLN GLN A . n 
A 1 157  PHE 157  279  279  PHE PHE A . n 
A 1 158  TYR 158  280  280  TYR TYR A . n 
A 1 159  PRO 159  281  281  PRO PRO A . n 
A 1 160  TYR 160  282  282  TYR TYR A . n 
A 1 161  ASP 161  283  283  ASP ASP A . n 
A 1 162  MET 162  284  284  MET MET A . n 
A 1 163  PRO 163  285  285  PRO PRO A . n 
A 1 164  CYS 164  286  286  CYS CYS A . n 
A 1 165  ILE 165  287  287  ILE ILE A . n 
A 1 166  GLY 166  288  288  GLY GLY A . n 
A 1 167  ALA 167  289  289  ALA ALA A . n 
A 1 168  CYS 168  290  290  CYS CYS A . n 
A 1 169  GLU 169  291  291  GLU GLU A . n 
A 1 170  MET 170  292  292  MET MET A . n 
A 1 171  ALA 171  293  293  ALA ALA A . n 
A 1 172  GLN 172  294  294  GLN GLN A . n 
A 1 173  ARG 173  295  295  ARG ARG A . n 
A 1 174  ASP 174  296  296  ASP ASP A . n 
A 1 175  TYR 175  297  297  TYR TYR A . n 
A 1 176  TRP 176  298  298  TRP TRP A . n 
A 1 177  HIS 177  299  299  HIS HIS A . n 
A 1 178  LEU 178  300  300  LEU LEU A . n 
A 1 179  GLN 179  301  301  GLN GLN A . n 
A 1 180  ARG 180  302  302  ARG ARG A . n 
A 1 181  LEU 181  303  303  LEU LEU A . n 
A 1 182  ALA 182  304  304  ALA ALA A . n 
A 1 183  ILE 183  305  305  ILE ILE A . n 
A 1 184  SER 184  306  306  SER SER A . n 
A 1 185  HIS 185  307  307  HIS HIS A . n 
A 1 186  LEU 186  308  308  LEU LEU A . n 
A 1 187  VAL 187  309  309  VAL VAL A . n 
A 1 188  GLU 188  310  310  GLU GLU A . n 
A 1 189  ARG 189  311  311  ARG ARG A . n 
A 1 190  THR 190  312  312  THR THR A . n 
A 1 191  GLN 191  313  313  GLN GLN A . n 
A 1 192  PRO 192  314  314  PRO PRO A . n 
A 1 193  GLN 193  315  315  GLN GLN A . n 
A 1 194  LEU 194  316  316  LEU LEU A . n 
A 1 195  GLU 195  317  317  GLU GLU A . n 
A 1 196  ARG 196  318  318  ARG ARG A . n 
A 1 197  ALA 197  319  ?    ?   ?   A . n 
A 1 198  PRO 198  320  ?    ?   ?   A . n 
A 1 199  ARG 199  321  ?    ?   ?   A . n 
A 1 200  ALA 200  322  ?    ?   ?   A . n 
A 1 201  ASP 201  323  ?    ?   ?   A . n 
A 1 202  GLY 202  324  ?    ?   ?   A . n 
A 1 203  GLN 203  325  ?    ?   ?   A . n 
A 1 204  SER 204  326  ?    ?   ?   A . n 
A 1 205  THR 205  327  327  THR THR A . n 
A 1 206  PRO 206  328  328  PRO PRO A . n 
A 1 207  LEU 207  329  329  LEU LEU A . n 
A 1 208  THR 208  330  330  THR THR A . n 
A 1 209  ILE 209  331  331  ILE ILE A . n 
A 1 210  ARG 210  332  332  ARG ARG A . n 
A 1 211  TRP 211  333  333  TRP TRP A . n 
A 1 212  ALA 212  334  334  ALA ALA A . n 
A 1 213  MET 213  335  335  MET MET A . n 
A 1 214  HIS 214  336  336  HIS HIS A . n 
A 1 215  PHE 215  337  337  PHE PHE A . n 
A 1 216  PRO 216  338  338  PRO PRO A . n 
A 1 217  GLU 217  339  339  GLU GLU A . n 
A 1 218  HIS 218  340  340  HIS HIS A . n 
A 1 219  TYR 219  341  341  TYR TYR A . n 
A 1 220  LEU 220  342  ?    ?   ?   A . n 
A 1 221  ALA 221  343  ?    ?   ?   A . n 
A 1 222  SER 222  344  ?    ?   ?   A . n 
A 1 223  ARG 223  345  ?    ?   ?   A . n 
A 1 224  PRO 224  346  346  PRO PRO A . n 
A 1 225  PHE 225  347  347  PHE PHE A . n 
A 1 226  ASN 226  348  348  ASN ASN A . n 
A 1 227  ILE 227  349  349  ILE ILE A . n 
A 1 228  GLN 228  350  350  GLN GLN A . n 
A 1 229  TYR 229  351  351  TYR TYR A . n 
A 1 230  GLN 230  352  352  GLN GLN A . n 
A 1 231  PHE 231  353  353  PHE PHE A . n 
A 1 232  VAL 232  354  354  VAL VAL A . n 
A 1 233  ASP 233  355  355  ASP ASP A . n 
A 1 234  HIS 234  356  ?    ?   ?   A . n 
A 1 235  HIS 235  357  ?    ?   ?   A . n 
A 1 236  GLY 236  358  ?    ?   ?   A . n 
A 1 237  GLU 237  359  ?    ?   ?   A . n 
A 1 238  GLU 238  360  ?    ?   ?   A . n 
A 1 239  LEU 239  361  ?    ?   ?   A . n 
A 1 240  ASP 240  362  ?    ?   ?   A . n 
A 1 241  LEU 241  363  ?    ?   ?   A . n 
A 1 242  GLU 242  364  ?    ?   ?   A . n 
A 1 243  GLN 243  365  ?    ?   ?   A . n 
A 1 244  GLU 244  366  ?    ?   ?   A . n 
A 1 245  ASP 245  367  ?    ?   ?   A . n 
A 1 246  GLN 246  368  ?    ?   ?   A . n 
A 1 247  ASP 247  369  ?    ?   ?   A . n 
A 1 248  ALA 248  370  ?    ?   ?   A . n 
A 1 249  SER 249  371  ?    ?   ?   A . n 
A 1 250  GLY 250  372  ?    ?   ?   A . n 
A 1 251  GLU 251  373  ?    ?   ?   A . n 
A 1 252  THR 252  374  ?    ?   ?   A . n 
A 1 253  GLY 253  375  ?    ?   ?   A . n 
A 1 254  SER 254  376  ?    ?   ?   A . n 
A 1 255  SER 255  377  377  SER SER A . n 
A 1 256  ALA 256  378  378  ALA ALA A . n 
A 1 257  TRP 257  379  379  TRP TRP A . n 
A 1 258  PHE 258  380  380  PHE PHE A . n 
A 1 259  ASN 259  381  381  ASN ASN A . n 
A 1 260  LEU 260  382  382  LEU LEU A . n 
A 1 261  ALA 261  383  383  ALA ALA A . n 
A 1 262  ASP 262  384  384  ASP ASP A . n 
A 1 263  TYR 263  385  385  TYR TYR A . n 
A 1 264  ASP 264  386  386  ASP ASP A . n 
A 1 265  CYS 265  387  387  CYS CYS A . n 
A 1 266  ASP 266  388  388  ASP ASP A . n 
A 1 267  GLU 267  389  389  GLU GLU A . n 
A 1 268  TYR 268  390  390  TYR TYR A . n 
A 1 269  TYR 269  391  391  TYR TYR A . n 
A 1 270  VAL 270  392  392  VAL VAL A . n 
A 1 271  CYS 271  393  393  CYS CYS A . n 
A 1 272  GLU 272  394  394  GLU GLU A . n 
A 1 273  ILE 273  395  395  ILE ILE A . n 
A 1 274  LEU 274  396  396  LEU LEU A . n 
A 1 275  GLU 275  397  397  GLU GLU A . n 
A 1 276  ALA 276  398  398  ALA ALA A . n 
A 1 277  LEU 277  399  399  LEU LEU A . n 
A 1 278  ILE 278  400  400  ILE ILE A . n 
A 1 279  PRO 279  401  401  PRO PRO A . n 
A 1 280  TYR 280  402  402  TYR TYR A . n 
A 1 281  THR 281  403  403  THR THR A . n 
A 1 282  GLN 282  404  404  GLN GLN A . n 
A 1 283  TYR 283  405  405  TYR TYR A . n 
A 1 284  ARG 284  406  406  ARG ARG A . n 
A 1 285  PHE 285  407  407  PHE PHE A . n 
A 1 286  ARG 286  408  408  ARG ARG A . n 
A 1 287  PHE 287  409  409  PHE PHE A . n 
A 1 288  GLU 288  410  410  GLU GLU A . n 
A 1 289  LEU 289  411  411  LEU LEU A . n 
A 1 290  PRO 290  412  412  PRO PRO A . n 
A 1 291  PHE 291  413  413  PHE PHE A . n 
A 1 292  GLY 292  414  414  GLY GLY A . n 
A 1 293  GLU 293  415  415  GLU GLU A . n 
A 1 294  ASN 294  416  416  ASN ASN A . n 
A 1 295  ARG 295  417  417  ARG ARG A . n 
A 1 296  ASP 296  418  418  ASP ASP A . n 
A 1 297  GLU 297  419  419  GLU GLU A . n 
A 1 298  VAL 298  420  420  VAL VAL A . n 
A 1 299  LEU 299  421  421  LEU LEU A . n 
A 1 300  TYR 300  422  422  TYR TYR A . n 
A 1 301  SER 301  423  423  SER SER A . n 
A 1 302  PRO 302  424  424  PRO PRO A . n 
A 1 303  ALA 303  425  425  ALA ALA A . n 
A 1 304  THR 304  426  426  THR THR A . n 
A 1 305  PRO 305  427  427  PRO PRO A . n 
A 1 306  ALA 306  428  428  ALA ALA A . n 
A 1 307  TYR 307  429  429  TYR TYR A . n 
A 1 308  GLN 308  430  430  GLN GLN A . n 
A 1 309  THR 309  431  431  THR THR A . n 
A 1 310  PRO 310  432  432  PRO PRO A . n 
A 1 311  PRO 311  433  433  PRO PRO A . n 
A 1 312  GLU 312  434  434  GLU GLU A . n 
A 1 313  GLY 313  435  435  GLY GLY A . n 
A 1 314  ALA 314  436  436  ALA ALA A . n 
A 1 315  PRO 315  437  437  PRO PRO A . n 
A 1 316  ILE 316  438  438  ILE ILE A . n 
A 1 317  SER 317  439  439  SER SER A . n 
A 1 318  ALA 318  440  440  ALA ALA A . n 
A 1 319  PRO 319  441  441  PRO PRO A . n 
A 1 320  VAL 320  442  442  VAL VAL A . n 
A 1 321  ILE 321  443  443  ILE ILE A . n 
A 1 322  GLU 322  444  444  GLU GLU A . n 
A 1 323  HIS 323  445  445  HIS HIS A . n 
A 1 324  LEU 324  446  446  LEU LEU A . n 
A 1 325  MET 325  447  447  MET MET A . n 
A 1 326  GLY 326  448  448  GLY GLY A . n 
A 1 327  LEU 327  449  449  LEU LEU A . n 
A 1 328  ASP 328  450  450  ASP ASP A . n 
A 1 329  ASP 329  451  451  ASP ASP A . n 
A 1 330  SER 330  452  452  SER SER A . n 
A 1 331  HIS 331  453  453  HIS HIS A . n 
A 1 332  LEU 332  454  454  LEU LEU A . n 
A 1 333  ALA 333  455  455  ALA ALA A . n 
A 1 334  VAL 334  456  456  VAL VAL A . n 
A 1 335  HIS 335  457  457  HIS HIS A . n 
A 1 336  TRP 336  458  458  TRP TRP A . n 
A 1 337  HIS 337  459  459  HIS HIS A . n 
A 1 338  PRO 338  460  460  PRO PRO A . n 
A 1 339  GLY 339  461  461  GLY GLY A . n 
A 1 340  ARG 340  462  462  ARG ARG A . n 
A 1 341  PHE 341  463  463  PHE PHE A . n 
A 1 342  THR 342  464  464  THR THR A . n 
A 1 343  ASN 343  465  465  ASN ASN A . n 
A 1 344  GLY 344  466  466  GLY GLY A . n 
A 1 345  PRO 345  467  467  PRO PRO A . n 
A 1 346  ILE 346  468  468  ILE ILE A . n 
A 1 347  GLU 347  469  469  GLU GLU A . n 
A 1 348  GLY 348  470  470  GLY GLY A . n 
A 1 349  TYR 349  471  471  TYR TYR A . n 
A 1 350  ARG 350  472  472  ARG ARG A . n 
A 1 351  LEU 351  473  473  LEU LEU A . n 
A 1 352  ARG 352  474  474  ARG ARG A . n 
A 1 353  LEU 353  475  475  LEU LEU A . n 
A 1 354  SER 354  476  476  SER SER A . n 
A 1 355  SER 355  477  477  SER SER A . n 
A 1 356  SER 356  478  478  SER SER A . n 
A 1 357  GLU 357  479  479  GLU GLU A . n 
A 1 358  GLY 358  480  480  GLY GLY A . n 
A 1 359  ASN 359  481  481  ASN ASN A . n 
A 1 360  ALA 360  482  482  ALA ALA A . n 
A 1 361  THR 361  483  483  THR THR A . n 
A 1 362  SER 362  484  484  SER SER A . n 
A 1 363  GLU 363  485  485  GLU GLU A . n 
A 1 364  GLN 364  486  486  GLN GLN A . n 
A 1 365  LEU 365  487  487  LEU LEU A . n 
A 1 366  VAL 366  488  488  VAL VAL A . n 
A 1 367  PRO 367  489  489  PRO PRO A . n 
A 1 368  ALA 368  490  490  ALA ALA A . n 
A 1 369  GLY 369  491  491  GLY GLY A . n 
A 1 370  ARG 370  492  492  ARG ARG A . n 
A 1 371  GLY 371  493  493  GLY GLY A . n 
A 1 372  SER 372  494  494  SER SER A . n 
A 1 373  TYR 373  495  495  TYR TYR A . n 
A 1 374  ILE 374  496  496  ILE ILE A . n 
A 1 375  PHE 375  497  497  PHE PHE A . n 
A 1 376  SER 376  498  498  SER SER A . n 
A 1 377  GLN 377  499  499  GLN GLN A . n 
A 1 378  LEU 378  500  500  LEU LEU A . n 
A 1 379  GLN 379  501  501  GLN GLN A . n 
A 1 380  ALA 380  502  502  ALA ALA A . n 
A 1 381  GLY 381  503  503  GLY GLY A . n 
A 1 382  THR 382  504  504  THR THR A . n 
A 1 383  ASN 383  505  505  ASN ASN A . n 
A 1 384  TYR 384  506  506  TYR TYR A . n 
A 1 385  THR 385  507  507  THR THR A . n 
A 1 386  LEU 386  508  508  LEU LEU A . n 
A 1 387  ALA 387  509  509  ALA ALA A . n 
A 1 388  LEU 388  510  510  LEU LEU A . n 
A 1 389  SER 389  511  511  SER SER A . n 
A 1 390  MET 390  512  512  MET MET A . n 
A 1 391  ILE 391  513  513  ILE ILE A . n 
A 1 392  ASN 392  514  514  ASN ASN A . n 
A 1 393  LYS 393  515  515  LYS LYS A . n 
A 1 394  GLN 394  516  516  GLN GLN A . n 
A 1 395  GLY 395  517  517  GLY GLY A . n 
A 1 396  GLU 396  518  518  GLU GLU A . n 
A 1 397  GLY 397  519  519  GLY GLY A . n 
A 1 398  PRO 398  520  520  PRO PRO A . n 
A 1 399  VAL 399  521  521  VAL VAL A . n 
A 1 400  ALA 400  522  522  ALA ALA A . n 
A 1 401  LYS 401  523  523  LYS LYS A . n 
A 1 402  GLY 402  524  524  GLY GLY A . n 
A 1 403  PHE 403  525  525  PHE PHE A . n 
A 1 404  VAL 404  526  526  VAL VAL A . n 
A 1 405  GLN 405  527  527  GLN GLN A . n 
A 1 406  THR 406  528  528  THR THR A . n 
A 1 407  HIS 407  529  529  HIS HIS A . n 
A 1 408  SER 408  530  530  SER SER A . n 
A 1 409  ALA 409  531  531  ALA ALA A . n 
A 1 410  ARG 410  532  532  ARG ARG A . n 
A 1 411  ASN 411  533  533  ASN ASN A . n 
A 1 412  GLU 412  534  534  GLU GLU A . n 
A 1 413  LYS 413  535  535  LYS LYS A . n 
A 1 414  PRO 414  536  536  PRO PRO A . n 
A 1 415  ALA 415  537  537  ALA ALA A . n 
A 1 416  LYS 416  538  538  LYS LYS A . n 
A 1 417  ASP 417  539  539  ASP ASP A . n 
A 1 418  LEU 418  540  540  LEU LEU A . n 
A 1 419  THR 419  541  541  THR THR A . n 
A 1 420  GLU 420  542  542  GLU GLU A . n 
A 1 421  SER 421  543  543  SER SER A . n 
A 1 422  VAL 422  544  544  VAL VAL A . n 
A 1 423  LEU 423  545  545  LEU LEU A . n 
A 1 424  LEU 424  546  546  LEU LEU A . n 
A 1 425  VAL 425  547  547  VAL VAL A . n 
A 1 426  GLY 426  548  548  GLY GLY A . n 
A 1 427  ARG 427  549  549  ARG ARG A . n 
A 1 428  ARG 428  550  550  ARG ARG A . n 
A 1 429  ALA 429  551  551  ALA ALA A . n 
A 1 430  VAL 430  552  552  VAL VAL A . n 
A 1 431  MET 431  553  553  MET MET A . n 
A 1 432  TRP 432  554  554  TRP TRP A . n 
A 1 433  GLN 433  555  555  GLN GLN A . n 
A 1 434  SER 434  556  556  SER SER A . n 
A 1 435  LEU 435  557  557  LEU LEU A . n 
A 1 436  GLU 436  558  558  GLU GLU A . n 
A 1 437  PRO 437  559  559  PRO PRO A . n 
A 1 438  ALA 438  560  560  ALA ALA A . n 
A 1 439  GLY 439  561  561  GLY GLY A . n 
A 1 440  GLU 440  562  562  GLU GLU A . n 
A 1 441  ASN 441  563  563  ASN ASN A . n 
A 1 442  SER 442  564  564  SER SER A . n 
A 1 443  MET 443  565  565  MET MET A . n 
A 1 444  ILE 444  566  566  ILE ILE A . n 
A 1 445  TYR 445  567  567  TYR TYR A . n 
A 1 446  GLN 446  568  568  GLN GLN A . n 
A 1 447  SER 447  569  569  SER SER A . n 
A 1 448  GLN 448  570  570  GLN GLN A . n 
A 1 449  GLU 449  571  571  GLU GLU A . n 
A 1 450  GLU 450  572  572  GLU GLU A . n 
A 1 451  LEU 451  573  573  LEU LEU A . n 
A 1 452  ALA 452  574  574  ALA ALA A . n 
A 1 453  ASP 453  575  575  ASP ASP A . n 
A 1 454  ILE 454  576  576  ILE ILE A . n 
A 1 455  ALA 455  577  577  ALA ALA A . n 
A 1 456  TRP 456  578  578  TRP TRP A . n 
A 1 457  SER 457  579  579  SER SER A . n 
A 1 458  LYS 458  580  580  LYS LYS A . n 
A 1 459  ARG 459  581  581  ARG ARG A . n 
A 1 460  GLU 460  582  582  GLU GLU A . n 
A 1 461  GLN 461  583  583  GLN GLN A . n 
A 1 462  GLN 462  584  584  GLN GLN A . n 
A 1 463  LEU 463  585  585  LEU LEU A . n 
A 1 464  TRP 464  586  586  TRP TRP A . n 
A 1 465  LEU 465  587  587  LEU LEU A . n 
A 1 466  LEU 466  588  588  LEU LEU A . n 
A 1 467  ASN 467  589  589  ASN ASN A . n 
A 1 468  VAL 468  590  590  VAL VAL A . n 
A 1 469  HIS 469  591  591  HIS HIS A . n 
A 1 470  GLY 470  592  592  GLY GLY A . n 
A 1 471  GLU 471  593  593  GLU GLU A . n 
A 1 472  LEU 472  594  594  LEU LEU A . n 
A 1 473  ARG 473  595  595  ARG ARG A . n 
A 1 474  SER 474  596  596  SER SER A . n 
A 1 475  LEU 475  597  597  LEU LEU A . n 
A 1 476  LYS 476  598  598  LYS LYS A . n 
A 1 477  PHE 477  599  599  PHE PHE A . n 
A 1 478  GLU 478  600  600  GLU GLU A . n 
A 1 479  SER 479  601  601  SER SER A . n 
A 1 480  GLY 480  602  602  GLY GLY A . n 
A 1 481  GLN 481  603  603  GLN GLN A . n 
A 1 482  MET 482  604  604  MET MET A . n 
A 1 483  VAL 483  605  605  VAL VAL A . n 
A 1 484  SER 484  606  606  SER SER A . n 
A 1 485  PRO 485  607  607  PRO PRO A . n 
A 1 486  ALA 486  608  608  ALA ALA A . n 
A 1 487  GLN 487  609  609  GLN GLN A . n 
A 1 488  GLN 488  610  610  GLN GLN A . n 
A 1 489  LEU 489  611  611  LEU LEU A . n 
A 1 490  LYS 490  612  612  LYS LYS A . n 
A 1 491  LEU 491  613  613  LEU LEU A . n 
A 1 492  ASP 492  614  614  ASP ASP A . n 
A 1 493  LEU 493  615  615  LEU LEU A . n 
A 1 494  GLY 494  616  616  GLY GLY A . n 
A 1 495  ASN 495  617  617  ASN ASN A . n 
A 1 496  ILE 496  618  618  ILE ILE A . n 
A 1 497  SER 497  619  619  SER SER A . n 
A 1 498  SER 498  620  620  SER SER A . n 
A 1 499  GLY 499  621  621  GLY GLY A . n 
A 1 500  ARG 500  622  622  ARG ARG A . n 
A 1 501  TRP 501  623  623  TRP TRP A . n 
A 1 502  VAL 502  624  624  VAL VAL A . n 
A 1 503  PRO 503  625  625  PRO PRO A . n 
A 1 504  ARG 504  626  626  ARG ARG A . n 
A 1 505  ARG 505  627  627  ARG ARG A . n 
A 1 506  LEU 506  628  628  LEU LEU A . n 
A 1 507  SER 507  629  629  SER SER A . n 
A 1 508  PHE 508  630  630  PHE PHE A . n 
A 1 509  ASP 509  631  631  ASP ASP A . n 
A 1 510  TRP 510  632  632  TRP TRP A . n 
A 1 511  LEU 511  633  633  LEU LEU A . n 
A 1 512  HIS 512  634  634  HIS HIS A . n 
A 1 513  HIS 513  635  635  HIS HIS A . n 
A 1 514  ARG 514  636  636  ARG ARG A . n 
A 1 515  LEU 515  637  637  LEU LEU A . n 
A 1 516  TYR 516  638  638  TYR TYR A . n 
A 1 517  PHE 517  639  639  PHE PHE A . n 
A 1 518  ALA 518  640  640  ALA ALA A . n 
A 1 519  MET 519  641  641  MET MET A . n 
A 1 520  GLU 520  642  642  GLU GLU A . n 
A 1 521  SER 521  643  643  SER SER A . n 
A 1 522  PRO 522  644  644  PRO PRO A . n 
A 1 523  GLU 523  645  645  GLU GLU A . n 
A 1 524  ARG 524  646  ?    ?   ?   A . n 
A 1 525  ASN 525  647  ?    ?   ?   A . n 
A 1 526  GLN 526  648  ?    ?   ?   A . n 
A 1 527  SER 527  649  ?    ?   ?   A . n 
A 1 528  SER 528  650  650  SER SER A . n 
A 1 529  PHE 529  651  651  PHE PHE A . n 
A 1 530  GLN 530  652  652  GLN GLN A . n 
A 1 531  ILE 531  653  653  ILE ILE A . n 
A 1 532  ILE 532  654  654  ILE ILE A . n 
A 1 533  SER 533  655  655  SER SER A . n 
A 1 534  THR 534  656  656  THR THR A . n 
A 1 535  ASP 535  657  657  ASP ASP A . n 
A 1 536  LEU 536  658  658  LEU LEU A . n 
A 1 537  LEU 537  659  659  LEU LEU A . n 
A 1 538  GLY 538  660  660  GLY GLY A . n 
A 1 539  GLU 539  661  661  GLU GLU A . n 
A 1 540  SER 540  662  662  SER SER A . n 
A 1 541  ALA 541  663  663  ALA ALA A . n 
A 1 542  GLN 542  664  664  GLN GLN A . n 
A 1 543  LYS 543  665  665  LYS LYS A . n 
A 1 544  VAL 544  666  666  VAL VAL A . n 
A 1 545  GLY 545  667  667  GLY GLY A . n 
A 1 546  GLU 546  668  668  GLU GLU A . n 
A 1 547  SER 547  669  669  SER SER A . n 
A 1 548  PHE 548  670  670  PHE PHE A . n 
A 1 549  ASP 549  671  671  ASP ASP A . n 
A 1 550  LEU 550  672  672  LEU LEU A . n 
A 1 551  PRO 551  673  673  PRO PRO A . n 
A 1 552  VAL 552  674  674  VAL VAL A . n 
A 1 553  GLU 553  675  675  GLU GLU A . n 
A 1 554  GLN 554  676  676  GLN GLN A . n 
A 1 555  LEU 555  677  677  LEU LEU A . n 
A 1 556  GLU 556  678  678  GLU GLU A . n 
A 1 557  VAL 557  679  679  VAL VAL A . n 
A 1 558  ASP 558  680  680  ASP ASP A . n 
A 1 559  ALA 559  681  681  ALA ALA A . n 
A 1 560  LEU 560  682  682  LEU LEU A . n 
A 1 561  ASN 561  683  683  ASN ASN A . n 
A 1 562  GLY 562  684  684  GLY GLY A . n 
A 1 563  TRP 563  685  685  TRP TRP A . n 
A 1 564  ILE 564  686  686  ILE ILE A . n 
A 1 565  PHE 565  687  687  PHE PHE A . n 
A 1 566  TRP 566  688  688  TRP TRP A . n 
A 1 567  ARG 567  689  689  ARG ARG A . n 
A 1 568  ASN 568  690  690  ASN ASN A . n 
A 1 569  GLU 569  691  691  GLU GLU A . n 
A 1 570  GLU 570  692  692  GLU GLU A . n 
A 1 571  SER 571  693  693  SER SER A . n 
A 1 572  LEU 572  694  694  LEU LEU A . n 
A 1 573  TRP 573  695  695  TRP TRP A . n 
A 1 574  ARG 574  696  696  ARG ARG A . n 
A 1 575  GLN 575  697  697  GLN GLN A . n 
A 1 576  ASP 576  698  698  ASP ASP A . n 
A 1 577  LEU 577  699  699  LEU LEU A . n 
A 1 578  HIS 578  700  700  HIS HIS A . n 
A 1 579  GLY 579  701  701  GLY GLY A . n 
A 1 580  ARG 580  702  702  ARG ARG A . n 
A 1 581  MET 581  703  703  MET MET A . n 
A 1 582  ILE 582  704  704  ILE ILE A . n 
A 1 583  HIS 583  705  705  HIS HIS A . n 
A 1 584  ARG 584  706  706  ARG ARG A . n 
A 1 585  LEU 585  707  707  LEU LEU A . n 
A 1 586  LEU 586  708  708  LEU LEU A . n 
A 1 587  ARG 587  709  709  ARG ARG A . n 
A 1 588  ILE 588  710  710  ILE ILE A . n 
A 1 589  ARG 589  711  711  ARG ARG A . n 
A 1 590  GLN 590  712  712  GLN GLN A . n 
A 1 591  PRO 591  713  713  PRO PRO A . n 
A 1 592  GLY 592  714  714  GLY GLY A . n 
A 1 593  TRP 593  715  715  TRP TRP A . n 
A 1 594  PHE 594  716  716  PHE PHE A . n 
A 1 595  LEU 595  717  717  LEU LEU A . n 
A 1 596  VAL 596  718  718  VAL VAL A . n 
A 1 597  GLN 597  719  719  GLN GLN A . n 
A 1 598  PRO 598  720  720  PRO PRO A . n 
A 1 599  GLN 599  721  721  GLN GLN A . n 
A 1 600  HIS 600  722  722  HIS HIS A . n 
A 1 601  PHE 601  723  723  PHE PHE A . n 
A 1 602  ILE 602  724  724  ILE ILE A . n 
A 1 603  ILE 603  725  725  ILE ILE A . n 
A 1 604  HIS 604  726  726  HIS HIS A . n 
A 1 605  LEU 605  727  727  LEU LEU A . n 
A 1 606  MET 606  728  728  MET MET A . n 
A 1 607  LEU 607  729  729  LEU LEU A . n 
A 1 608  PRO 608  730  730  PRO PRO A . n 
A 1 609  GLN 609  731  731  GLN GLN A . n 
A 1 610  GLU 610  732  732  GLU GLU A . n 
A 1 611  GLY 611  733  733  GLY GLY A . n 
A 1 612  LYS 612  734  734  LYS LYS A . n 
A 1 613  PHE 613  735  735  PHE PHE A . n 
A 1 614  LEU 614  736  736  LEU LEU A . n 
A 1 615  GLU 615  737  737  GLU GLU A . n 
A 1 616  ILE 616  738  738  ILE ILE A . n 
A 1 617  SER 617  739  739  SER SER A . n 
A 1 618  TYR 618  740  740  TYR TYR A . n 
A 1 619  ASP 619  741  741  ASP ASP A . n 
A 1 620  GLY 620  742  742  GLY GLY A . n 
A 1 621  GLY 621  743  743  GLY GLY A . n 
A 1 622  PHE 622  744  744  PHE PHE A . n 
A 1 623  LYS 623  745  745  LYS LYS A . n 
A 1 624  HIS 624  746  746  HIS HIS A . n 
A 1 625  PRO 625  747  747  PRO PRO A . n 
A 1 626  LEU 626  748  748  LEU LEU A . n 
A 1 627  PRO 627  749  749  PRO PRO A . n 
A 1 628  LEU 628  750  750  LEU LEU A . n 
A 1 629  PRO 629  751  751  PRO PRO A . n 
A 1 630  PRO 630  752  752  PRO PRO A . n 
A 1 631  PRO 631  753  753  PRO PRO A . n 
A 1 632  SER 632  754  ?    ?   ?   A . n 
A 1 633  ASN 633  755  ?    ?   ?   A . n 
A 1 634  GLY 634  756  ?    ?   ?   A . n 
A 1 635  ALA 635  757  ?    ?   ?   A . n 
A 1 636  GLY 636  758  ?    ?   ?   A . n 
A 1 637  ASN 637  759  ?    ?   ?   A . n 
A 1 638  GLY 638  760  ?    ?   ?   A . n 
A 1 639  PRO 639  761  ?    ?   ?   A . n 
A 1 640  ALA 640  762  ?    ?   ?   A . n 
A 1 641  SER 641  763  ?    ?   ?   A . n 
A 1 642  SER 642  764  ?    ?   ?   A . n 
A 1 643  HIS 643  765  765  HIS HIS A . n 
A 1 644  TRP 644  766  766  TRP TRP A . n 
A 1 645  GLN 645  767  767  GLN GLN A . n 
A 1 646  SER 646  768  768  SER SER A . n 
A 1 647  PHE 647  769  769  PHE PHE A . n 
A 1 648  ALA 648  770  770  ALA ALA A . n 
A 1 649  LEU 649  771  771  LEU LEU A . n 
A 1 650  LEU 650  772  772  LEU LEU A . n 
A 1 651  GLY 651  773  773  GLY GLY A . n 
A 1 652  ARG 652  774  774  ARG ARG A . n 
A 1 653  SER 653  775  775  SER SER A . n 
A 1 654  LEU 654  776  776  LEU LEU A . n 
A 1 655  LEU 655  777  777  LEU LEU A . n 
A 1 656  LEU 656  778  778  LEU LEU A . n 
A 1 657  PRO 657  779  779  PRO PRO A . n 
A 1 658  ASP 658  780  780  ASP ASP A . n 
A 1 659  SER 659  781  781  SER SER A . n 
A 1 660  GLY 660  782  782  GLY GLY A . n 
A 1 661  GLN 661  783  783  GLN GLN A . n 
A 1 662  LEU 662  784  784  LEU LEU A . n 
A 1 663  ILE 663  785  785  ILE ILE A . n 
A 1 664  LEU 664  786  786  LEU LEU A . n 
A 1 665  VAL 665  787  787  VAL VAL A . n 
A 1 666  GLU 666  788  788  GLU GLU A . n 
A 1 667  GLN 667  789  789  GLN GLN A . n 
A 1 668  GLN 668  790  790  GLN GLN A . n 
A 1 669  GLY 669  791  791  GLY GLY A . n 
A 1 670  GLN 670  792  792  GLN GLN A . n 
A 1 671  ALA 671  793  793  ALA ALA A . n 
A 1 672  ALA 672  794  794  ALA ALA A . n 
A 1 673  SER 673  795  795  SER SER A . n 
A 1 674  PRO 674  796  796  PRO PRO A . n 
A 1 675  SER 675  797  797  SER SER A . n 
A 1 676  ALA 676  798  798  ALA ALA A . n 
A 1 677  SER 677  799  799  SER SER A . n 
A 1 678  TRP 678  800  800  TRP TRP A . n 
A 1 679  PRO 679  801  801  PRO PRO A . n 
A 1 680  LEU 680  802  802  LEU LEU A . n 
A 1 681  LYS 681  803  803  LYS LYS A . n 
A 1 682  ASN 682  804  804  ASN ASN A . n 
A 1 683  LEU 683  805  805  LEU LEU A . n 
A 1 684  PRO 684  806  806  PRO PRO A . n 
A 1 685  ASP 685  807  807  ASP ASP A . n 
A 1 686  CYS 686  808  808  CYS CYS A . n 
A 1 687  TRP 687  809  809  TRP TRP A . n 
A 1 688  ALA 688  810  810  ALA ALA A . n 
A 1 689  VAL 689  811  811  VAL VAL A . n 
A 1 690  ILE 690  812  812  ILE ILE A . n 
A 1 691  LEU 691  813  813  LEU LEU A . n 
A 1 692  LEU 692  814  814  LEU LEU A . n 
A 1 693  VAL 693  815  815  VAL VAL A . n 
A 1 694  PRO 694  816  816  PRO PRO A . n 
A 1 695  GLU 695  817  817  GLU GLU A . n 
A 1 696  SER 696  818  818  SER SER A . n 
A 1 697  GLN 697  819  819  GLN GLN A . n 
A 1 698  PRO 698  820  820  PRO PRO A . n 
A 1 699  LEU 699  821  821  LEU LEU A . n 
A 1 700  THR 700  822  822  THR THR A . n 
A 1 701  SER 701  823  823  SER SER A . n 
A 1 702  ALA 702  824  824  ALA ALA A . n 
A 1 703  GLY 703  825  825  GLY GLY A . n 
A 1 704  GLY 704  826  826  GLY GLY A . n 
A 1 705  LYS 705  827  827  LYS LYS A . n 
A 1 706  PRO 706  828  828  PRO PRO A . n 
A 1 707  HIS 707  829  829  HIS HIS A . n 
A 1 708  SER 708  830  830  SER SER A . n 
A 1 709  LEU 709  831  831  LEU LEU A . n 
A 1 710  LYS 710  832  832  LYS LYS A . n 
A 1 711  ALA 711  833  833  ALA ALA A . n 
A 1 712  LEU 712  834  834  LEU LEU A . n 
A 1 713  LEU 713  835  835  LEU LEU A . n 
A 1 714  GLY 714  836  836  GLY GLY A . n 
A 1 715  ALA 715  837  837  ALA ALA A . n 
A 1 716  GLN 716  838  838  GLN GLN A . n 
A 1 717  ALA 717  839  839  ALA ALA A . n 
A 1 718  ALA 718  840  840  ALA ALA A . n 
A 1 719  LYS 719  841  841  LYS LYS A . n 
A 1 720  ILE 720  842  842  ILE ILE A . n 
A 1 721  SER 721  843  843  SER SER A . n 
A 1 722  TRP 722  844  844  TRP TRP A . n 
A 1 723  LYS 723  845  845  LYS LYS A . n 
A 1 724  GLU 724  846  846  GLU GLU A . n 
A 1 725  PRO 725  847  847  PRO PRO A . n 
A 1 726  GLU 726  848  848  GLU GLU A . n 
A 1 727  ARG 727  849  849  ARG ARG A . n 
A 1 728  ASN 728  850  850  ASN ASN A . n 
A 1 729  PRO 729  851  851  PRO PRO A . n 
A 1 730  TYR 730  852  852  TYR TYR A . n 
A 1 731  GLN 731  853  853  GLN GLN A . n 
A 1 732  SER 732  854  854  SER SER A . n 
A 1 733  ALA 733  855  855  ALA ALA A . n 
A 1 734  ASP 734  856  856  ASP ASP A . n 
A 1 735  ALA 735  857  857  ALA ALA A . n 
A 1 736  ALA 736  858  858  ALA ALA A . n 
A 1 737  ARG 737  859  859  ARG ARG A . n 
A 1 738  SER 738  860  860  SER SER A . n 
A 1 739  TRP 739  861  861  TRP TRP A . n 
A 1 740  SER 740  862  862  SER SER A . n 
A 1 741  TYR 741  863  863  TYR TYR A . n 
A 1 742  GLU 742  864  864  GLU GLU A . n 
A 1 743  LEU 743  865  865  LEU LEU A . n 
A 1 744  GLU 744  866  866  GLU GLU A . n 
A 1 745  VAL 745  867  867  VAL VAL A . n 
A 1 746  LEU 746  868  868  LEU LEU A . n 
A 1 747  ASP 747  869  869  ASP ASP A . n 
A 1 748  VAL 748  870  870  VAL VAL A . n 
A 1 749  ALA 749  871  871  ALA ALA A . n 
A 1 750  SER 750  872  872  SER SER A . n 
A 1 751  GLN 751  873  873  GLN GLN A . n 
A 1 752  SER 752  874  874  SER SER A . n 
A 1 753  ALA 753  875  875  ALA ALA A . n 
A 1 754  PHE 754  876  876  PHE PHE A . n 
A 1 755  SER 755  877  877  SER SER A . n 
A 1 756  ILE 756  878  878  ILE ILE A . n 
A 1 757  ARG 757  879  879  ARG ARG A . n 
A 1 758  ASN 758  880  880  ASN ASN A . n 
A 1 759  ILE 759  881  881  ILE ILE A . n 
A 1 760  ARG 760  882  882  ARG ARG A . n 
A 1 761  GLY 761  883  883  GLY GLY A . n 
A 1 762  PRO 762  884  884  PRO PRO A . n 
A 1 763  ILE 763  885  885  ILE ILE A . n 
A 1 764  PHE 764  886  886  PHE PHE A . n 
A 1 765  GLY 765  887  887  GLY GLY A . n 
A 1 766  LEU 766  888  888  LEU LEU A . n 
A 1 767  GLN 767  889  889  GLN GLN A . n 
A 1 768  ARG 768  890  890  ARG ARG A . n 
A 1 769  LEU 769  891  891  LEU LEU A . n 
A 1 770  GLN 770  892  892  GLN GLN A . n 
A 1 771  PRO 771  893  893  PRO PRO A . n 
A 1 772  ASP 772  894  894  ASP ASP A . n 
A 1 773  ASN 773  895  895  ASN ASN A . n 
A 1 774  LEU 774  896  896  LEU LEU A . n 
A 1 775  TYR 775  897  897  TYR TYR A . n 
A 1 776  GLN 776  898  898  GLN GLN A . n 
A 1 777  LEU 777  899  899  LEU LEU A . n 
A 1 778  ARG 778  900  900  ARG ARG A . n 
A 1 779  VAL 779  901  901  VAL VAL A . n 
A 1 780  ARG 780  902  902  ARG ARG A . n 
A 1 781  ALA 781  903  903  ALA ALA A . n 
A 1 782  ILE 782  904  904  ILE ILE A . n 
A 1 783  ASN 783  905  905  ASN ASN A . n 
A 1 784  VAL 784  906  906  VAL VAL A . n 
A 1 785  ASP 785  907  907  ASP ASP A . n 
A 1 786  GLY 786  908  908  GLY GLY A . n 
A 1 787  GLU 787  909  909  GLU GLU A . n 
A 1 788  PRO 788  910  910  PRO PRO A . n 
A 1 789  GLY 789  911  911  GLY GLY A . n 
A 1 790  GLU 790  912  912  GLU GLU A . n 
A 1 791  TRP 791  913  913  TRP TRP A . n 
A 1 792  THR 792  914  914  THR THR A . n 
A 1 793  GLU 793  915  915  GLU GLU A . n 
A 1 794  PRO 794  916  916  PRO PRO A . n 
A 1 795  LEU 795  917  917  LEU LEU A . n 
A 1 796  ALA 796  918  918  ALA ALA A . n 
A 1 797  ALA 797  919  919  ALA ALA A . n 
A 1 798  ARG 798  920  920  ARG ARG A . n 
A 1 799  THR 799  921  921  THR THR A . n 
A 1 800  TRP 800  922  922  TRP TRP A . n 
A 1 801  PRO 801  923  923  PRO PRO A . n 
A 1 802  LEU 802  924  924  LEU LEU A . n 
A 1 803  GLY 803  925  925  GLY GLY A . n 
A 1 804  PRO 804  926  926  PRO PRO A . n 
A 1 805  HIS 805  927  927  HIS HIS A . n 
A 1 806  ARG 806  928  928  ARG ARG A . n 
A 1 807  LEU 807  929  929  LEU LEU A . n 
A 1 808  ARG 808  930  930  ARG ARG A . n 
A 1 809  TRP 809  931  931  TRP TRP A . n 
A 1 810  ALA 810  932  932  ALA ALA A . n 
A 1 811  SER 811  933  933  SER SER A . n 
A 1 812  ARG 812  934  934  ARG ARG A . n 
A 1 813  GLN 813  935  935  GLN GLN A . n 
A 1 814  GLY 814  936  936  GLY GLY A . n 
A 1 815  SER 815  937  937  SER SER A . n 
A 1 816  VAL 816  938  938  VAL VAL A . n 
A 1 817  ILE 817  939  939  ILE ILE A . n 
A 1 818  HIS 818  940  940  HIS HIS A . n 
A 1 819  THR 819  941  941  THR THR A . n 
A 1 820  ASN 820  942  942  ASN ASN A . n 
A 1 821  GLU 821  943  943  GLU GLU A . n 
A 1 822  LEU 822  944  944  LEU LEU A . n 
A 1 823  GLY 823  945  945  GLY GLY A . n 
A 1 824  GLU 824  946  946  GLU GLU A . n 
A 1 825  GLY 825  947  947  GLY GLY A . n 
A 1 826  LEU 826  948  948  LEU LEU A . n 
A 1 827  GLU 827  949  949  GLU GLU A . n 
A 1 828  VAL 828  950  950  VAL VAL A . n 
A 1 829  GLN 829  951  951  GLN GLN A . n 
A 1 830  GLN 830  952  952  GLN GLN A . n 
A 1 831  GLU 831  953  953  GLU GLU A . n 
A 1 832  GLN 832  954  954  GLN GLN A . n 
A 1 833  LEU 833  955  955  LEU LEU A . n 
A 1 834  GLU 834  956  956  GLU GLU A . n 
A 1 835  ARG 835  957  957  ARG ARG A . n 
A 1 836  LEU 836  958  958  LEU LEU A . n 
A 1 837  PRO 837  959  959  PRO PRO A . n 
A 1 838  GLY 838  960  960  GLY GLY A . n 
A 1 839  PRO 839  961  961  PRO PRO A . n 
A 1 840  MET 840  962  962  MET MET A . n 
A 1 841  THR 841  963  963  THR THR A . n 
A 1 842  MET 842  964  964  MET MET A . n 
A 1 843  VAL 843  965  965  VAL VAL A . n 
A 1 844  ASN 844  966  966  ASN ASN A . n 
A 1 845  GLU 845  967  967  GLU GLU A . n 
A 1 846  SER 846  968  968  SER SER A . n 
A 1 847  VAL 847  969  969  VAL VAL A . n 
A 1 848  GLY 848  970  970  GLY GLY A . n 
A 1 849  TYR 849  971  971  TYR TYR A . n 
A 1 850  TYR 850  972  972  TYR TYR A . n 
A 1 851  VAL 851  973  973  VAL VAL A . n 
A 1 852  THR 852  974  974  THR THR A . n 
A 1 853  GLY 853  975  975  GLY GLY A . n 
A 1 854  ASP 854  976  976  ASP ASP A . n 
A 1 855  GLY 855  977  977  GLY GLY A . n 
A 1 856  LEU 856  978  978  LEU LEU A . n 
A 1 857  LEU 857  979  979  LEU LEU A . n 
A 1 858  HIS 858  980  980  HIS HIS A . n 
A 1 859  CYS 859  981  981  CYS CYS A . n 
A 1 860  ILE 860  982  982  ILE ILE A . n 
A 1 861  ASN 861  983  983  ASN ASN A . n 
A 1 862  LEU 862  984  984  LEU LEU A . n 
A 1 863  VAL 863  985  985  VAL VAL A . n 
A 1 864  HIS 864  986  986  HIS HIS A . n 
A 1 865  SER 865  987  987  SER SER A . n 
A 1 866  GLN 866  988  988  GLN GLN A . n 
A 1 867  TRP 867  989  989  TRP TRP A . n 
A 1 868  GLY 868  990  990  GLY GLY A . n 
A 1 869  CYS 869  991  991  CYS CYS A . n 
A 1 870  PRO 870  992  992  PRO PRO A . n 
A 1 871  ILE 871  993  993  ILE ILE A . n 
A 1 872  SER 872  994  994  SER SER A . n 
A 1 873  GLU 873  995  995  GLU GLU A . n 
A 1 874  PRO 874  996  996  PRO PRO A . n 
A 1 875  LEU 875  997  997  LEU LEU A . n 
A 1 876  GLN 876  998  998  GLN GLN A . n 
A 1 877  HIS 877  999  999  HIS HIS A . n 
A 1 878  VAL 878  1000 1000 VAL VAL A . n 
A 1 879  GLY 879  1001 1001 GLY GLY A . n 
A 1 880  SER 880  1002 1002 SER SER A . n 
A 1 881  VAL 881  1003 1003 VAL VAL A . n 
A 1 882  THR 882  1004 1004 THR THR A . n 
A 1 883  TYR 883  1005 1005 TYR TYR A . n 
A 1 884  ASP 884  1006 1006 ASP ASP A . n 
A 1 885  TRP 885  1007 1007 TRP TRP A . n 
A 1 886  ARG 886  1008 1008 ARG ARG A . n 
A 1 887  GLY 887  1009 1009 GLY GLY A . n 
A 1 888  GLY 888  1010 1010 GLY GLY A . n 
A 1 889  ARG 889  1011 1011 ARG ARG A . n 
A 1 890  VAL 890  1012 1012 VAL VAL A . n 
A 1 891  TYR 891  1013 1013 TYR TYR A . n 
A 1 892  TRP 892  1014 1014 TRP TRP A . n 
A 1 893  THR 893  1015 1015 THR THR A . n 
A 1 894  ASP 894  1016 1016 ASP ASP A . n 
A 1 895  LEU 895  1017 1017 LEU LEU A . n 
A 1 896  ALA 896  1018 1018 ALA ALA A . n 
A 1 897  ARG 897  1019 1019 ARG ARG A . n 
A 1 898  ASN 898  1020 1020 ASN ASN A . n 
A 1 899  CYS 899  1021 1021 CYS CYS A . n 
A 1 900  VAL 900  1022 1022 VAL VAL A . n 
A 1 901  VAL 901  1023 1023 VAL VAL A . n 
A 1 902  ARG 902  1024 1024 ARG ARG A . n 
A 1 903  MET 903  1025 1025 MET MET A . n 
A 1 904  ASP 904  1026 1026 ASP ASP A . n 
A 1 905  PRO 905  1027 1027 PRO PRO A . n 
A 1 906  TRP 906  1028 1028 TRP TRP A . n 
A 1 907  SER 907  1029 1029 SER SER A . n 
A 1 908  GLY 908  1030 1030 GLY GLY A . n 
A 1 909  SER 909  1031 1031 SER SER A . n 
A 1 910  ARG 910  1032 1032 ARG ARG A . n 
A 1 911  GLU 911  1033 1033 GLU GLU A . n 
A 1 912  LEU 912  1034 1034 LEU LEU A . n 
A 1 913  LEU 913  1035 1035 LEU LEU A . n 
A 1 914  PRO 914  1036 1036 PRO PRO A . n 
A 1 915  VAL 915  1037 1037 VAL VAL A . n 
A 1 916  PHE 916  1038 1038 PHE PHE A . n 
A 1 917  GLU 917  1039 1039 GLU GLU A . n 
A 1 918  ALA 918  1040 1040 ALA ALA A . n 
A 1 919  ASN 919  1041 1041 ASN ASN A . n 
A 1 920  PHE 920  1042 1042 PHE PHE A . n 
A 1 921  LEU 921  1043 1043 LEU LEU A . n 
A 1 922  ALA 922  1044 1044 ALA ALA A . n 
A 1 923  LEU 923  1045 1045 LEU LEU A . n 
A 1 924  ASP 924  1046 1046 ASP ASP A . n 
A 1 925  PRO 925  1047 1047 PRO PRO A . n 
A 1 926  ARG 926  1048 1048 ARG ARG A . n 
A 1 927  GLN 927  1049 1049 GLN GLN A . n 
A 1 928  GLY 928  1050 1050 GLY GLY A . n 
A 1 929  HIS 929  1051 1051 HIS HIS A . n 
A 1 930  LEU 930  1052 1052 LEU LEU A . n 
A 1 931  TYR 931  1053 1053 TYR TYR A . n 
A 1 932  TYR 932  1054 1054 TYR TYR A . n 
A 1 933  ALA 933  1055 1055 ALA ALA A . n 
A 1 934  THR 934  1056 1056 THR THR A . n 
A 1 935  SER 935  1057 1057 SER SER A . n 
A 1 936  SER 936  1058 1058 SER SER A . n 
A 1 937  GLN 937  1059 1059 GLN GLN A . n 
A 1 938  LEU 938  1060 1060 LEU LEU A . n 
A 1 939  SER 939  1061 1061 SER SER A . n 
A 1 940  ARG 940  1062 1062 ARG ARG A . n 
A 1 941  HIS 941  1063 1063 HIS HIS A . n 
A 1 942  GLY 942  1064 1064 GLY GLY A . n 
A 1 943  SER 943  1065 1065 SER SER A . n 
A 1 944  THR 944  1066 1066 THR THR A . n 
A 1 945  PRO 945  1067 1067 PRO PRO A . n 
A 1 946  ASP 946  1068 1068 ASP ASP A . n 
A 1 947  GLU 947  1069 1069 GLU GLU A . n 
A 1 948  ALA 948  1070 1070 ALA ALA A . n 
A 1 949  VAL 949  1071 1071 VAL VAL A . n 
A 1 950  THR 950  1072 1072 THR THR A . n 
A 1 951  TYR 951  1073 1073 TYR TYR A . n 
A 1 952  TYR 952  1074 1074 TYR TYR A . n 
A 1 953  ARG 953  1075 1075 ARG ARG A . n 
A 1 954  VAL 954  1076 1076 VAL VAL A . n 
A 1 955  ASN 955  1077 1077 ASN ASN A . n 
A 1 956  GLY 956  1078 1078 GLY GLY A . n 
A 1 957  LEU 957  1079 1079 LEU LEU A . n 
A 1 958  GLU 958  1080 1080 GLU GLU A . n 
A 1 959  GLY 959  1081 1081 GLY GLY A . n 
A 1 960  SER 960  1082 1082 SER SER A . n 
A 1 961  ILE 961  1083 1083 ILE ILE A . n 
A 1 962  ALA 962  1084 1084 ALA ALA A . n 
A 1 963  SER 963  1085 1085 SER SER A . n 
A 1 964  PHE 964  1086 1086 PHE PHE A . n 
A 1 965  VAL 965  1087 1087 VAL VAL A . n 
A 1 966  LEU 966  1088 1088 LEU LEU A . n 
A 1 967  ASP 967  1089 1089 ASP ASP A . n 
A 1 968  THR 968  1090 1090 THR THR A . n 
A 1 969  GLN 969  1091 1091 GLN GLN A . n 
A 1 970  GLN 970  1092 1092 GLN GLN A . n 
A 1 971  ASP 971  1093 1093 ASP ASP A . n 
A 1 972  GLN 972  1094 1094 GLN GLN A . n 
A 1 973  LEU 973  1095 1095 LEU LEU A . n 
A 1 974  PHE 974  1096 1096 PHE PHE A . n 
A 1 975  TRP 975  1097 1097 TRP TRP A . n 
A 1 976  LEU 976  1098 1098 LEU LEU A . n 
A 1 977  VAL 977  1099 1099 VAL VAL A . n 
A 1 978  LYS 978  1100 1100 LYS LYS A . n 
A 1 979  GLY 979  1101 1101 GLY GLY A . n 
A 1 980  SER 980  1102 1102 SER SER A . n 
A 1 981  GLY 981  1103 1103 GLY GLY A . n 
A 1 982  ALA 982  1104 1104 ALA ALA A . n 
A 1 983  LEU 983  1105 1105 LEU LEU A . n 
A 1 984  ARG 984  1106 1106 ARG ARG A . n 
A 1 985  LEU 985  1107 1107 LEU LEU A . n 
A 1 986  TYR 986  1108 1108 TYR TYR A . n 
A 1 987  ARG 987  1109 1109 ARG ARG A . n 
A 1 988  ALA 988  1110 1110 ALA ALA A . n 
A 1 989  PRO 989  1111 1111 PRO PRO A . n 
A 1 990  LEU 990  1112 1112 LEU LEU A . n 
A 1 991  THR 991  1113 1113 THR THR A . n 
A 1 992  ALA 992  1114 1114 ALA ALA A . n 
A 1 993  GLY 993  1115 1115 GLY GLY A . n 
A 1 994  GLY 994  1116 1116 GLY GLY A . n 
A 1 995  ASP 995  1117 1117 ASP ASP A . n 
A 1 996  SER 996  1118 1118 SER SER A . n 
A 1 997  LEU 997  1119 1119 LEU LEU A . n 
A 1 998  GLN 998  1120 1120 GLN GLN A . n 
A 1 999  MET 999  1121 1121 MET MET A . n 
A 1 1000 ILE 1000 1122 1122 ILE ILE A . n 
A 1 1001 GLN 1001 1123 1123 GLN GLN A . n 
A 1 1002 GLN 1002 1124 1124 GLN GLN A . n 
A 1 1003 ILE 1003 1125 1125 ILE ILE A . n 
A 1 1004 LYS 1004 1126 1126 LYS LYS A . n 
A 1 1005 GLY 1005 1127 1127 GLY GLY A . n 
A 1 1006 VAL 1006 1128 1128 VAL VAL A . n 
A 1 1007 PHE 1007 1129 1129 PHE PHE A . n 
A 1 1008 GLN 1008 1130 1130 GLN GLN A . n 
A 1 1009 ALA 1009 1131 1131 ALA ALA A . n 
A 1 1010 VAL 1010 1132 1132 VAL VAL A . n 
A 1 1011 PRO 1011 1133 1133 PRO PRO A . n 
A 1 1012 ASP 1012 1134 1134 ASP ASP A . n 
A 1 1013 SER 1013 1135 1135 SER SER A . n 
A 1 1014 LEU 1014 1136 1136 LEU LEU A . n 
A 1 1015 GLN 1015 1137 1137 GLN GLN A . n 
A 1 1016 LEU 1016 1138 1138 LEU LEU A . n 
A 1 1017 LEU 1017 1139 1139 LEU LEU A . n 
A 1 1018 ARG 1018 1140 1140 ARG ARG A . n 
A 1 1019 PRO 1019 1141 1141 PRO PRO A . n 
A 1 1020 LEU 1020 1142 1142 LEU LEU A . n 
A 1 1021 GLY 1021 1143 1143 GLY GLY A . n 
A 1 1022 ALA 1022 1144 1144 ALA ALA A . n 
A 1 1023 LEU 1023 1145 1145 LEU LEU A . n 
A 1 1024 LEU 1024 1146 1146 LEU LEU A . n 
A 1 1025 TRP 1025 1147 1147 TRP TRP A . n 
A 1 1026 LEU 1026 1148 1148 LEU LEU A . n 
A 1 1027 GLU 1027 1149 1149 GLU GLU A . n 
A 1 1028 ARG 1028 1150 1150 ARG ARG A . n 
A 1 1029 SER 1029 1151 1151 SER SER A . n 
A 1 1030 GLY 1030 1152 1152 GLY GLY A . n 
A 1 1031 ARG 1031 1153 1153 ARG ARG A . n 
A 1 1032 ARG 1032 1154 1154 ARG ARG A . n 
A 1 1033 ALA 1033 1155 1155 ALA ALA A . n 
A 1 1034 ARG 1034 1156 1156 ARG ARG A . n 
A 1 1035 LEU 1035 1157 1157 LEU LEU A . n 
A 1 1036 VAL 1036 1158 1158 VAL VAL A . n 
A 1 1037 ARG 1037 1159 1159 ARG ARG A . n 
A 1 1038 LEU 1038 1160 1160 LEU LEU A . n 
A 1 1039 ALA 1039 1161 1161 ALA ALA A . n 
A 1 1040 ALA 1040 1162 1162 ALA ALA A . n 
A 1 1041 PRO 1041 1163 1163 PRO PRO A . n 
A 1 1042 LEU 1042 1164 1164 LEU LEU A . n 
A 1 1043 ASP 1043 1165 1165 ASP ASP A . n 
A 1 1044 VAL 1044 1166 1166 VAL VAL A . n 
A 1 1045 MET 1045 1167 1167 MET MET A . n 
A 1 1046 GLU 1046 1168 1168 GLU GLU A . n 
A 1 1047 LEU 1047 1169 1169 LEU LEU A . n 
A 1 1048 PRO 1048 1170 1170 PRO PRO A . n 
A 1 1049 THR 1049 1171 1171 THR THR A . n 
A 1 1050 PRO 1050 1172 1172 PRO PRO A . n 
A 1 1051 ASP 1051 1173 1173 ASP ASP A . n 
A 1 1052 GLN 1052 1174 1174 GLN GLN A . n 
A 1 1053 ALA 1053 1175 1175 ALA ALA A . n 
A 1 1054 SER 1054 1176 1176 SER SER A . n 
A 1 1055 PRO 1055 1177 1177 PRO PRO A . n 
A 1 1056 ALA 1056 1178 1178 ALA ALA A . n 
A 1 1057 SER 1057 1179 1179 SER SER A . n 
A 1 1058 ALA 1058 1180 1180 ALA ALA A . n 
A 1 1059 LEU 1059 1181 1181 LEU LEU A . n 
A 1 1060 GLN 1060 1182 1182 GLN GLN A . n 
A 1 1061 LEU 1061 1183 1183 LEU LEU A . n 
A 1 1062 LEU 1062 1184 1184 LEU LEU A . n 
A 1 1063 ASP 1063 1185 1185 ASP ASP A . n 
A 1 1064 PRO 1064 1186 1186 PRO PRO A . n 
A 1 1065 GLN 1065 1187 1187 GLN GLN A . n 
A 1 1066 PRO 1066 1188 1188 PRO PRO A . n 
A 1 1067 LEU 1067 1189 1189 LEU LEU A . n 
A 1 1068 PRO 1068 1190 1190 PRO PRO A . n 
A 1 1069 PRO 1069 1191 1191 PRO PRO A . n 
A 1 1070 ARG 1070 1192 1192 ARG ARG A . n 
A 1 1071 ASP 1071 1193 1193 ASP ASP A . n 
A 1 1072 GLU 1072 1194 1194 GLU GLU A . n 
A 1 1073 GLY 1073 1195 1195 GLY GLY A . n 
A 1 1074 VAL 1074 1196 1196 VAL VAL A . n 
A 1 1075 ILE 1075 1197 1197 ILE ILE A . n 
A 1 1076 PRO 1076 1198 1198 PRO PRO A . n 
A 1 1077 MET 1077 1199 1199 MET MET A . n 
A 1 1078 THR 1078 1200 1200 THR THR A . n 
A 1 1079 VAL 1079 1201 1201 VAL VAL A . n 
A 1 1080 LEU 1080 1202 1202 LEU LEU A . n 
A 1 1081 PRO 1081 1203 1203 PRO PRO A . n 
A 1 1082 ASP 1082 1204 1204 ASP ASP A . n 
A 1 1083 SER 1083 1205 1205 SER SER A . n 
A 1 1084 VAL 1084 1206 1206 VAL VAL A . n 
A 1 1085 ARG 1085 1207 1207 ARG ARG A . n 
A 1 1086 LEU 1086 1208 1208 LEU LEU A . n 
A 1 1087 ASP 1087 1209 1209 ASP ASP A . n 
A 1 1088 ASP 1088 1210 1210 ASP ASP A . n 
A 1 1089 GLY 1089 1211 1211 GLY GLY A . n 
A 1 1090 HIS 1090 1212 1212 HIS HIS A . n 
A 1 1091 TRP 1091 1213 1213 TRP TRP A . n 
A 1 1092 ASP 1092 1214 1214 ASP ASP A . n 
A 1 1093 ASP 1093 1215 1215 ASP ASP A . n 
A 1 1094 PHE 1094 1216 1216 PHE PHE A . n 
A 1 1095 HIS 1095 1217 1217 HIS HIS A . n 
A 1 1096 VAL 1096 1218 1218 VAL VAL A . n 
A 1 1097 ARG 1097 1219 1219 ARG ARG A . n 
A 1 1098 TRP 1098 1220 1220 TRP TRP A . n 
A 1 1099 GLN 1099 1221 1221 GLN GLN A . n 
A 1 1100 PRO 1100 1222 1222 PRO PRO A . n 
A 1 1101 SER 1101 1223 1223 SER SER A . n 
A 1 1102 THR 1102 1224 1224 THR THR A . n 
A 1 1103 SER 1103 1225 1225 SER SER A . n 
A 1 1104 GLY 1104 1226 1226 GLY GLY A . n 
A 1 1105 GLY 1105 1227 1227 GLY GLY A . n 
A 1 1106 ASN 1106 1228 1228 ASN ASN A . n 
A 1 1107 HIS 1107 1229 1229 HIS HIS A . n 
A 1 1108 SER 1108 1230 1230 SER SER A . n 
A 1 1109 VAL 1109 1231 1231 VAL VAL A . n 
A 1 1110 SER 1110 1232 1232 SER SER A . n 
A 1 1111 TYR 1111 1233 1233 TYR TYR A . n 
A 1 1112 ARG 1112 1234 1234 ARG ARG A . n 
A 1 1113 LEU 1113 1235 1235 LEU LEU A . n 
A 1 1114 LEU 1114 1236 1236 LEU LEU A . n 
A 1 1115 LEU 1115 1237 1237 LEU LEU A . n 
A 1 1116 GLU 1116 1238 1238 GLU GLU A . n 
A 1 1117 PHE 1117 1239 1239 PHE PHE A . n 
A 1 1118 GLY 1118 1240 1240 GLY GLY A . n 
A 1 1119 GLN 1119 1241 1241 GLN GLN A . n 
A 1 1120 ARG 1120 1242 1242 ARG ARG A . n 
A 1 1121 LEU 1121 1243 1243 LEU LEU A . n 
A 1 1122 GLN 1122 1244 1244 GLN GLN A . n 
A 1 1123 THR 1123 1245 1245 THR THR A . n 
A 1 1124 LEU 1124 1246 1246 LEU LEU A . n 
A 1 1125 ASP 1125 1247 1247 ASP ASP A . n 
A 1 1126 LEU 1126 1248 1248 LEU LEU A . n 
A 1 1127 SER 1127 1249 1249 SER SER A . n 
A 1 1128 THR 1128 1250 1250 THR THR A . n 
A 1 1129 PRO 1129 1251 1251 PRO PRO A . n 
A 1 1130 PHE 1130 1252 1252 PHE PHE A . n 
A 1 1131 ALA 1131 1253 1253 ALA ALA A . n 
A 1 1132 ARG 1132 1254 1254 ARG ARG A . n 
A 1 1133 LEU 1133 1255 1255 LEU LEU A . n 
A 1 1134 THR 1134 1256 1256 THR THR A . n 
A 1 1135 GLN 1135 1257 1257 GLN GLN A . n 
A 1 1136 LEU 1136 1258 1258 LEU LEU A . n 
A 1 1137 PRO 1137 1259 1259 PRO PRO A . n 
A 1 1138 GLN 1138 1260 1260 GLN GLN A . n 
A 1 1139 ALA 1139 1261 1261 ALA ALA A . n 
A 1 1140 GLN 1140 1262 1262 GLN GLN A . n 
A 1 1141 LEU 1141 1263 1263 LEU LEU A . n 
A 1 1142 GLN 1142 1264 1264 GLN GLN A . n 
A 1 1143 LEU 1143 1265 1265 LEU LEU A . n 
A 1 1144 LYS 1144 1266 1266 LYS LYS A . n 
A 1 1145 ILE 1145 1267 1267 ILE ILE A . n 
A 1 1146 SER 1146 1268 1268 SER SER A . n 
A 1 1147 ILE 1147 1269 1269 ILE ILE A . n 
A 1 1148 THR 1148 1270 1270 THR THR A . n 
A 1 1149 PRO 1149 1271 1271 PRO PRO A . n 
A 1 1150 ARG 1150 1272 1272 ARG ARG A . n 
A 1 1151 THR 1151 1273 1273 THR THR A . n 
A 1 1152 ALA 1152 1274 1274 ALA ALA A . n 
A 1 1153 TRP 1153 1275 1275 TRP TRP A . n 
A 1 1154 ARG 1154 1276 1276 ARG ARG A . n 
A 1 1155 SER 1155 1277 1277 SER SER A . n 
A 1 1156 GLY 1156 1278 1278 GLY GLY A . n 
A 1 1157 ASP 1157 1279 1279 ASP ASP A . n 
A 1 1158 THR 1158 1280 1280 THR THR A . n 
A 1 1159 THR 1159 1281 1281 THR THR A . n 
A 1 1160 ARG 1160 1282 1282 ARG ARG A . n 
A 1 1161 VAL 1161 1283 1283 VAL VAL A . n 
A 1 1162 GLN 1162 1284 1284 GLN GLN A . n 
A 1 1163 LEU 1163 1285 1285 LEU LEU A . n 
A 1 1164 THR 1164 1286 1286 THR THR A . n 
A 1 1165 THR 1165 1287 1287 THR THR A . n 
A 1 1166 PRO 1166 1288 ?    ?   ?   A . n 
A 1 1167 PRO 1167 1289 ?    ?   ?   A . n 
A 1 1168 VAL 1168 1290 ?    ?   ?   A . n 
A 1 1169 ALA 1169 1291 ?    ?   ?   A . n 
A 1 1170 PRO 1170 1292 ?    ?   ?   A . n 
A 1 1171 SER 1171 1293 ?    ?   ?   A . n 
A 1 1172 GLN 1172 1294 ?    ?   ?   A . n 
A 1 1173 PRO 1173 1295 ?    ?   ?   A . n 
A 1 1174 ARG 1174 1296 ?    ?   ?   A . n 
A 1 1175 ARG 1175 1297 ?    ?   ?   A . n 
A 1 1176 LEU 1176 1298 ?    ?   ?   A . n 
A 1 1177 ARG 1177 1299 ?    ?   ?   A . n 
A 1 1178 VAL 1178 1300 ?    ?   ?   A . n 
A 1 1179 PHE 1179 1301 ?    ?   ?   A . n 
A 1 1180 VAL 1180 1302 ?    ?   ?   A . n 
A 1 1181 GLU 1181 1303 ?    ?   ?   A . n 
A 1 1182 ARG 1182 1304 ?    ?   ?   A . n 
A 1 1183 LEU 1183 1305 ?    ?   ?   A . n 
A 1 1184 ALA 1184 1306 ?    ?   ?   A . n 
A 1 1185 THR 1185 1307 ?    ?   ?   A . n 
A 1 1186 ALA 1186 1308 ?    ?   ?   A . n 
A 1 1187 LEU 1187 1309 ?    ?   ?   A . n 
A 1 1188 GLN 1188 1310 ?    ?   ?   A . n 
A 1 1189 GLU 1189 1311 ?    ?   ?   A . n 
A 1 1190 ALA 1190 1312 ?    ?   ?   A . n 
A 1 1191 ASN 1191 1313 ?    ?   ?   A . n 
A 1 1192 VAL 1192 1314 ?    ?   ?   A . n 
A 1 1193 SER 1193 1315 ?    ?   ?   A . n 
A 1 1194 ALA 1194 1316 ?    ?   ?   A . n 
A 1 1195 VAL 1195 1317 ?    ?   ?   A . n 
A 1 1196 LEU 1196 1318 ?    ?   ?   A . n 
A 1 1197 ARG 1197 1319 ?    ?   ?   A . n 
A 1 1198 TRP 1198 1320 ?    ?   ?   A . n 
A 1 1199 ASP 1199 1321 ?    ?   ?   A . n 
A 1 1200 ALA 1200 1322 ?    ?   ?   A . n 
A 1 1201 PRO 1201 1323 ?    ?   ?   A . n 
A 1 1202 GLU 1202 1324 ?    ?   ?   A . n 
A 1 1203 GLN 1203 1325 ?    ?   ?   A . n 
A 1 1204 GLY 1204 1326 ?    ?   ?   A . n 
A 1 1205 GLN 1205 1327 ?    ?   ?   A . n 
A 1 1206 GLU 1206 1328 ?    ?   ?   A . n 
A 1 1207 ALA 1207 1329 ?    ?   ?   A . n 
A 1 1208 PRO 1208 1330 ?    ?   ?   A . n 
A 1 1209 MET 1209 1331 ?    ?   ?   A . n 
A 1 1210 GLN 1210 1332 ?    ?   ?   A . n 
A 1 1211 ALA 1211 1333 ?    ?   ?   A . n 
A 1 1212 LEU 1212 1334 ?    ?   ?   A . n 
A 1 1213 GLU 1213 1335 ?    ?   ?   A . n 
A 1 1214 TYR 1214 1336 ?    ?   ?   A . n 
A 1 1215 HIS 1215 1337 ?    ?   ?   A . n 
A 1 1216 ILE 1216 1338 ?    ?   ?   A . n 
A 1 1217 SER 1217 1339 ?    ?   ?   A . n 
A 1 1218 CYS 1218 1340 ?    ?   ?   A . n 
A 1 1219 TRP 1219 1341 ?    ?   ?   A . n 
A 1 1220 VAL 1220 1342 ?    ?   ?   A . n 
A 1 1221 GLY 1221 1343 ?    ?   ?   A . n 
A 1 1222 SER 1222 1344 ?    ?   ?   A . n 
A 1 1223 GLU 1223 1345 ?    ?   ?   A . n 
A 1 1224 LEU 1224 1346 ?    ?   ?   A . n 
A 1 1225 HIS 1225 1347 ?    ?   ?   A . n 
A 1 1226 GLU 1226 1348 ?    ?   ?   A . n 
A 1 1227 GLU 1227 1349 ?    ?   ?   A . n 
A 1 1228 LEU 1228 1350 ?    ?   ?   A . n 
A 1 1229 ARG 1229 1351 ?    ?   ?   A . n 
A 1 1230 LEU 1230 1352 ?    ?   ?   A . n 
A 1 1231 ASN 1231 1353 ?    ?   ?   A . n 
A 1 1232 GLN 1232 1354 ?    ?   ?   A . n 
A 1 1233 SER 1233 1355 ?    ?   ?   A . n 
A 1 1234 ALA 1234 1356 ?    ?   ?   A . n 
A 1 1235 LEU 1235 1357 ?    ?   ?   A . n 
A 1 1236 GLU 1236 1358 ?    ?   ?   A . n 
A 1 1237 ALA 1237 1359 ?    ?   ?   A . n 
A 1 1238 ARG 1238 1360 ?    ?   ?   A . n 
A 1 1239 VAL 1239 1361 ?    ?   ?   A . n 
A 1 1240 GLU 1240 1362 ?    ?   ?   A . n 
A 1 1241 HIS 1241 1363 ?    ?   ?   A . n 
A 1 1242 LEU 1242 1364 ?    ?   ?   A . n 
A 1 1243 GLN 1243 1365 ?    ?   ?   A . n 
A 1 1244 PRO 1244 1366 ?    ?   ?   A . n 
A 1 1245 ASP 1245 1367 ?    ?   ?   A . n 
A 1 1246 GLN 1246 1368 ?    ?   ?   A . n 
A 1 1247 THR 1247 1369 ?    ?   ?   A . n 
A 1 1248 TYR 1248 1370 ?    ?   ?   A . n 
A 1 1249 HIS 1249 1371 ?    ?   ?   A . n 
A 1 1250 PHE 1250 1372 ?    ?   ?   A . n 
A 1 1251 GLN 1251 1373 ?    ?   ?   A . n 
A 1 1252 VAL 1252 1374 ?    ?   ?   A . n 
A 1 1253 GLU 1253 1375 ?    ?   ?   A . n 
A 1 1254 ALA 1254 1376 ?    ?   ?   A . n 
A 1 1255 ARG 1255 1377 ?    ?   ?   A . n 
A 1 1256 VAL 1256 1378 ?    ?   ?   A . n 
A 1 1257 ALA 1257 1379 ?    ?   ?   A . n 
A 1 1258 ALA 1258 1380 ?    ?   ?   A . n 
A 1 1259 THR 1259 1381 ?    ?   ?   A . n 
A 1 1260 GLY 1260 1382 ?    ?   ?   A . n 
A 1 1261 ALA 1261 1383 ?    ?   ?   A . n 
A 1 1262 ALA 1262 1384 ?    ?   ?   A . n 
A 1 1263 ALA 1263 1385 ?    ?   ?   A . n 
A 1 1264 GLY 1264 1386 ?    ?   ?   A . n 
A 1 1265 ALA 1265 1387 ?    ?   ?   A . n 
A 1 1266 ALA 1266 1388 ?    ?   ?   A . n 
A 1 1267 SER 1267 1389 ?    ?   ?   A . n 
A 1 1268 HIS 1268 1390 ?    ?   ?   A . n 
A 1 1269 ALA 1269 1391 ?    ?   ?   A . n 
A 1 1270 LEU 1270 1392 ?    ?   ?   A . n 
A 1 1271 HIS 1271 1393 ?    ?   ?   A . n 
A 1 1272 VAL 1272 1394 ?    ?   ?   A . n 
A 1 1273 ALA 1273 1395 ?    ?   ?   A . n 
A 1 1274 PRO 1274 1396 ?    ?   ?   A . n 
A 1 1275 GLU 1275 1397 ?    ?   ?   A . n 
A 1 1276 VAL 1276 1398 ?    ?   ?   A . n 
A 1 1277 GLN 1277 1399 ?    ?   ?   A . n 
A 1 1278 ALA 1278 1400 ?    ?   ?   A . n 
A 1 1279 VAL 1279 1401 ?    ?   ?   A . n 
A 1 1280 PRO 1280 1402 ?    ?   ?   A . n 
A 1 1281 ARG 1281 1403 ?    ?   ?   A . n 
A 1 1282 VAL 1282 1404 ?    ?   ?   A . n 
A 1 1283 LEU 1283 1405 ?    ?   ?   A . n 
A 1 1284 TYR 1284 1406 ?    ?   ?   A . n 
A 1 1285 ALA 1285 1407 ?    ?   ?   A . n 
A 1 1286 ASN 1286 1408 ?    ?   ?   A . n 
A 1 1287 ALA 1287 1409 ?    ?   ?   A . n 
A 1 1288 GLU 1288 1410 ?    ?   ?   A . n 
A 1 1289 PHE 1289 1411 ?    ?   ?   A . n 
A 1 1290 ILE 1290 1412 ?    ?   ?   A . n 
A 1 1291 GLY 1291 1413 ?    ?   ?   A . n 
A 1 1292 GLU 1292 1414 ?    ?   ?   A . n 
A 1 1293 LEU 1293 1415 ?    ?   ?   A . n 
A 1 1294 ASP 1294 1416 ?    ?   ?   A . n 
A 1 1295 LEU 1295 1417 ?    ?   ?   A . n 
A 1 1296 ASP 1296 1418 ?    ?   ?   A . n 
A 1 1297 THR 1297 1419 ?    ?   ?   A . n 
A 1 1298 ARG 1298 1420 ?    ?   ?   A . n 
A 1 1299 ASN 1299 1421 ?    ?   ?   A . n 
A 1 1300 ARG 1300 1422 ?    ?   ?   A . n 
A 1 1301 ARG 1301 1423 ?    ?   ?   A . n 
A 1 1302 ARG 1302 1424 ?    ?   ?   A . n 
A 1 1303 LEU 1303 1425 ?    ?   ?   A . n 
A 1 1304 VAL 1304 1426 ?    ?   ?   A . n 
A 1 1305 HIS 1305 1427 ?    ?   ?   A . n 
A 1 1306 THR 1306 1428 ?    ?   ?   A . n 
A 1 1307 ALA 1307 1429 ?    ?   ?   A . n 
A 1 1308 SER 1308 1430 ?    ?   ?   A . n 
A 1 1309 PRO 1309 1431 ?    ?   ?   A . n 
A 1 1310 VAL 1310 1432 ?    ?   ?   A . n 
A 1 1311 GLU 1311 1433 ?    ?   ?   A . n 
A 1 1312 HIS 1312 1434 ?    ?   ?   A . n 
A 1 1313 LEU 1313 1435 ?    ?   ?   A . n 
A 1 1314 VAL 1314 1436 ?    ?   ?   A . n 
A 1 1315 GLY 1315 1437 ?    ?   ?   A . n 
A 1 1316 ILE 1316 1438 ?    ?   ?   A . n 
A 1 1317 GLU 1317 1439 ?    ?   ?   A . n 
A 1 1318 GLY 1318 1440 ?    ?   ?   A . n 
A 1 1319 GLU 1319 1441 ?    ?   ?   A . n 
A 1 1320 GLN 1320 1442 ?    ?   ?   A . n 
A 1 1321 ARG 1321 1443 ?    ?   ?   A . n 
A 1 1322 LEU 1322 1444 ?    ?   ?   A . n 
A 1 1323 LEU 1323 1445 ?    ?   ?   A . n 
A 1 1324 TRP 1324 1446 ?    ?   ?   A . n 
A 1 1325 VAL 1325 1447 ?    ?   ?   A . n 
A 1 1326 ASN 1326 1448 ?    ?   ?   A . n 
A 1 1327 GLU 1327 1449 ?    ?   ?   A . n 
A 1 1328 HIS 1328 1450 ?    ?   ?   A . n 
A 1 1329 VAL 1329 1451 ?    ?   ?   A . n 
A 1 1330 GLU 1330 1452 ?    ?   ?   A . n 
A 1 1331 LEU 1331 1453 ?    ?   ?   A . n 
A 1 1332 LEU 1332 1454 ?    ?   ?   A . n 
A 1 1333 THR 1333 1455 ?    ?   ?   A . n 
A 1 1334 HIS 1334 1456 ?    ?   ?   A . n 
A 1 1335 VAL 1335 1457 ?    ?   ?   A . n 
A 1 1336 PRO 1336 1458 ?    ?   ?   A . n 
A 1 1337 GLY 1337 1459 ?    ?   ?   A . n 
A 1 1338 SER 1338 1460 ?    ?   ?   A . n 
A 1 1339 ALA 1339 1461 ?    ?   ?   A . n 
A 1 1340 PRO 1340 1462 ?    ?   ?   A . n 
A 1 1341 ALA 1341 1463 ?    ?   ?   A . n 
A 1 1342 LYS 1342 1464 ?    ?   ?   A . n 
A 1 1343 LEU 1343 1465 ?    ?   ?   A . n 
A 1 1344 ALA 1344 1466 ?    ?   ?   A . n 
A 1 1345 ARG 1345 1467 ?    ?   ?   A . n 
A 1 1346 MET 1346 1468 ?    ?   ?   A . n 
A 1 1347 ARG 1347 1469 ?    ?   ?   A . n 
A 1 1348 ALA 1348 1470 ?    ?   ?   A . n 
A 1 1349 GLU 1349 1471 ?    ?   ?   A . n 
A 1 1350 VAL 1350 1472 ?    ?   ?   A . n 
A 1 1351 LEU 1351 1473 ?    ?   ?   A . n 
A 1 1352 ALA 1352 1474 ?    ?   ?   A . n 
A 1 1353 LEU 1353 1475 ?    ?   ?   A . n 
A 1 1354 ALA 1354 1476 ?    ?   ?   A . n 
A 1 1355 VAL 1355 1477 ?    ?   ?   A . n 
A 1 1356 ASP 1356 1478 ?    ?   ?   A . n 
A 1 1357 TRP 1357 1479 ?    ?   ?   A . n 
A 1 1358 ILE 1358 1480 ?    ?   ?   A . n 
A 1 1359 GLN 1359 1481 ?    ?   ?   A . n 
A 1 1360 ARG 1360 1482 ?    ?   ?   A . n 
A 1 1361 ILE 1361 1483 ?    ?   ?   A . n 
A 1 1362 VAL 1362 1484 ?    ?   ?   A . n 
A 1 1363 TYR 1363 1485 ?    ?   ?   A . n 
A 1 1364 TRP 1364 1486 ?    ?   ?   A . n 
A 1 1365 ALA 1365 1487 ?    ?   ?   A . n 
A 1 1366 GLU 1366 1488 ?    ?   ?   A . n 
A 1 1367 LEU 1367 1489 ?    ?   ?   A . n 
A 1 1368 ASP 1368 1490 ?    ?   ?   A . n 
A 1 1369 ALA 1369 1491 ?    ?   ?   A . n 
A 1 1370 THR 1370 1492 ?    ?   ?   A . n 
A 1 1371 ALA 1371 1493 ?    ?   ?   A . n 
A 1 1372 PRO 1372 1494 ?    ?   ?   A . n 
A 1 1373 GLN 1373 1495 ?    ?   ?   A . n 
A 1 1374 ALA 1374 1496 ?    ?   ?   A . n 
A 1 1375 ALA 1375 1497 ?    ?   ?   A . n 
A 1 1376 ILE 1376 1498 ?    ?   ?   A . n 
A 1 1377 ILE 1377 1499 ?    ?   ?   A . n 
A 1 1378 TYR 1378 1500 ?    ?   ?   A . n 
A 1 1379 ARG 1379 1501 ?    ?   ?   A . n 
A 1 1380 LEU 1380 1502 ?    ?   ?   A . n 
A 1 1381 ASP 1381 1503 ?    ?   ?   A . n 
A 1 1382 LEU 1382 1504 ?    ?   ?   A . n 
A 1 1383 CYS 1383 1505 ?    ?   ?   A . n 
A 1 1384 ASN 1384 1506 ?    ?   ?   A . n 
A 1 1385 PHE 1385 1507 ?    ?   ?   A . n 
A 1 1386 GLU 1386 1508 ?    ?   ?   A . n 
A 1 1387 GLY 1387 1509 ?    ?   ?   A . n 
A 1 1388 LYS 1388 1510 ?    ?   ?   A . n 
A 1 1389 ILE 1389 1511 ?    ?   ?   A . n 
A 1 1390 LEU 1390 1512 ?    ?   ?   A . n 
A 1 1391 GLN 1391 1513 ?    ?   ?   A . n 
A 1 1392 GLY 1392 1514 ?    ?   ?   A . n 
A 1 1393 GLU 1393 1515 ?    ?   ?   A . n 
A 1 1394 ARG 1394 1516 ?    ?   ?   A . n 
A 1 1395 VAL 1395 1517 ?    ?   ?   A . n 
A 1 1396 TRP 1396 1518 ?    ?   ?   A . n 
A 1 1397 SER 1397 1519 ?    ?   ?   A . n 
A 1 1398 THR 1398 1520 ?    ?   ?   A . n 
A 1 1399 PRO 1399 1521 ?    ?   ?   A . n 
A 1 1400 ARG 1400 1522 ?    ?   ?   A . n 
A 1 1401 GLY 1401 1523 ?    ?   ?   A . n 
A 1 1402 ARG 1402 1524 ?    ?   ?   A . n 
A 1 1403 LEU 1403 1525 ?    ?   ?   A . n 
A 1 1404 LEU 1404 1526 ?    ?   ?   A . n 
A 1 1405 LYS 1405 1527 ?    ?   ?   A . n 
A 1 1406 ASP 1406 1528 ?    ?   ?   A . n 
A 1 1407 LEU 1407 1529 ?    ?   ?   A . n 
A 1 1408 VAL 1408 1530 ?    ?   ?   A . n 
A 1 1409 ALA 1409 1531 ?    ?   ?   A . n 
A 1 1410 LEU 1410 1532 ?    ?   ?   A . n 
A 1 1411 PRO 1411 1533 ?    ?   ?   A . n 
A 1 1412 GLN 1412 1534 ?    ?   ?   A . n 
A 1 1413 ALA 1413 1535 ?    ?   ?   A . n 
A 1 1414 GLN 1414 1536 ?    ?   ?   A . n 
A 1 1415 SER 1415 1537 ?    ?   ?   A . n 
A 1 1416 LEU 1416 1538 ?    ?   ?   A . n 
A 1 1417 ILE 1417 1539 ?    ?   ?   A . n 
A 1 1418 TRP 1418 1540 ?    ?   ?   A . n 
A 1 1419 LEU 1419 1541 ?    ?   ?   A . n 
A 1 1420 GLU 1420 1542 ?    ?   ?   A . n 
A 1 1421 TYR 1421 1543 ?    ?   ?   A . n 
A 1 1422 GLU 1422 1544 ?    ?   ?   A . n 
A 1 1423 GLN 1423 1545 ?    ?   ?   A . n 
A 1 1424 GLY 1424 1546 ?    ?   ?   A . n 
A 1 1425 SER 1425 1547 ?    ?   ?   A . n 
A 1 1426 PRO 1426 1548 ?    ?   ?   A . n 
A 1 1427 ARG 1427 1549 ?    ?   ?   A . n 
A 1 1428 ASN 1428 1550 ?    ?   ?   A . n 
A 1 1429 GLY 1429 1551 ?    ?   ?   A . n 
A 1 1430 SER 1430 1552 ?    ?   ?   A . n 
A 1 1431 LEU 1431 1553 ?    ?   ?   A . n 
A 1 1432 ARG 1432 1554 ?    ?   ?   A . n 
A 1 1433 GLY 1433 1555 ?    ?   ?   A . n 
A 1 1434 ARG 1434 1556 ?    ?   ?   A . n 
A 1 1435 ASN 1435 1557 ?    ?   ?   A . n 
A 1 1436 LEU 1436 1558 ?    ?   ?   A . n 
A 1 1437 THR 1437 1559 ?    ?   ?   A . n 
A 1 1438 ASP 1438 1560 ?    ?   ?   A . n 
A 1 1439 GLY 1439 1561 ?    ?   ?   A . n 
A 1 1440 SER 1440 1562 ?    ?   ?   A . n 
A 1 1441 GLU 1441 1563 ?    ?   ?   A . n 
A 1 1442 LEU 1442 1564 ?    ?   ?   A . n 
A 1 1443 GLU 1443 1565 ?    ?   ?   A . n 
A 1 1444 TRP 1444 1566 ?    ?   ?   A . n 
A 1 1445 ALA 1445 1567 ?    ?   ?   A . n 
A 1 1446 THR 1446 1568 ?    ?   ?   A . n 
A 1 1447 VAL 1447 1569 ?    ?   ?   A . n 
A 1 1448 GLN 1448 1570 ?    ?   ?   A . n 
A 1 1449 PRO 1449 1571 ?    ?   ?   A . n 
A 1 1450 LEU 1450 1572 ?    ?   ?   A . n 
A 1 1451 ILE 1451 1573 ?    ?   ?   A . n 
A 1 1452 ARG 1452 1574 ?    ?   ?   A . n 
A 1 1453 LEU 1453 1575 ?    ?   ?   A . n 
A 1 1454 HIS 1454 1576 ?    ?   ?   A . n 
A 1 1455 ALA 1455 1577 ?    ?   ?   A . n 
A 1 1456 GLY 1456 1578 ?    ?   ?   A . n 
A 1 1457 SER 1457 1579 ?    ?   ?   A . n 
A 1 1458 LEU 1458 1580 ?    ?   ?   A . n 
A 1 1459 GLU 1459 1581 ?    ?   ?   A . n 
A 1 1460 PRO 1460 1582 ?    ?   ?   A . n 
A 1 1461 GLY 1461 1583 ?    ?   ?   A . n 
A 1 1462 SER 1462 1584 ?    ?   ?   A . n 
A 1 1463 GLU 1463 1585 ?    ?   ?   A . n 
A 1 1464 THR 1464 1586 ?    ?   ?   A . n 
A 1 1465 LEU 1465 1587 ?    ?   ?   A . n 
A 1 1466 ASN 1466 1588 ?    ?   ?   A . n 
A 1 1467 LEU 1467 1589 ?    ?   ?   A . n 
A 1 1468 VAL 1468 1590 ?    ?   ?   A . n 
A 1 1469 ASP 1469 1591 ?    ?   ?   A . n 
A 1 1470 ASN 1470 1592 ?    ?   ?   A . n 
A 1 1471 GLN 1471 1593 ?    ?   ?   A . n 
A 1 1472 GLY 1472 1594 ?    ?   ?   A . n 
A 1 1473 LYS 1473 1595 ?    ?   ?   A . n 
A 1 1474 LEU 1474 1596 ?    ?   ?   A . n 
A 1 1475 CYS 1475 1597 ?    ?   ?   A . n 
A 1 1476 VAL 1476 1598 ?    ?   ?   A . n 
A 1 1477 TYR 1477 1599 ?    ?   ?   A . n 
A 1 1478 ASP 1478 1600 ?    ?   ?   A . n 
A 1 1479 VAL 1479 1601 ?    ?   ?   A . n 
A 1 1480 ALA 1480 1602 ?    ?   ?   A . n 
A 1 1481 ARG 1481 1603 ?    ?   ?   A . n 
A 1 1482 GLN 1482 1604 ?    ?   ?   A . n 
A 1 1483 LEU 1483 1605 ?    ?   ?   A . n 
A 1 1484 CYS 1484 1606 ?    ?   ?   A . n 
A 1 1485 THR 1485 1607 ?    ?   ?   A . n 
A 1 1486 ALA 1486 1608 ?    ?   ?   A . n 
A 1 1487 SER 1487 1609 ?    ?   ?   A . n 
A 1 1488 ALA 1488 1610 ?    ?   ?   A . n 
A 1 1489 LEU 1489 1611 ?    ?   ?   A . n 
A 1 1490 ARG 1490 1612 ?    ?   ?   A . n 
A 1 1491 ALA 1491 1613 ?    ?   ?   A . n 
A 1 1492 GLN 1492 1614 ?    ?   ?   A . n 
A 1 1493 LEU 1493 1615 ?    ?   ?   A . n 
A 1 1494 ASN 1494 1616 ?    ?   ?   A . n 
A 1 1495 LEU 1495 1617 ?    ?   ?   A . n 
A 1 1496 LEU 1496 1618 ?    ?   ?   A . n 
A 1 1497 GLY 1497 1619 ?    ?   ?   A . n 
A 1 1498 GLU 1498 1620 ?    ?   ?   A . n 
A 1 1499 ASP 1499 1621 ?    ?   ?   A . n 
A 1 1500 SER 1500 1622 ?    ?   ?   A . n 
A 1 1501 ILE 1501 1623 ?    ?   ?   A . n 
A 1 1502 ALA 1502 1624 ?    ?   ?   A . n 
A 1 1503 GLY 1503 1625 ?    ?   ?   A . n 
A 1 1504 GLN 1504 1626 ?    ?   ?   A . n 
A 1 1505 LEU 1505 1627 ?    ?   ?   A . n 
A 1 1506 ALA 1506 1628 ?    ?   ?   A . n 
A 1 1507 GLN 1507 1629 ?    ?   ?   A . n 
A 1 1508 ASP 1508 1630 ?    ?   ?   A . n 
A 1 1509 SER 1509 1631 ?    ?   ?   A . n 
A 1 1510 GLY 1510 1632 ?    ?   ?   A . n 
A 1 1511 TYR 1511 1633 ?    ?   ?   A . n 
A 1 1512 LEU 1512 1634 ?    ?   ?   A . n 
A 1 1513 TYR 1513 1635 ?    ?   ?   A . n 
A 1 1514 ALA 1514 1636 ?    ?   ?   A . n 
A 1 1515 VAL 1515 1637 ?    ?   ?   A . n 
A 1 1516 LYS 1516 1638 ?    ?   ?   A . n 
A 1 1517 ASN 1517 1639 ?    ?   ?   A . n 
A 1 1518 TRP 1518 1640 ?    ?   ?   A . n 
A 1 1519 SER 1519 1641 ?    ?   ?   A . n 
A 1 1520 ILE 1520 1642 ?    ?   ?   A . n 
A 1 1521 ARG 1521 1643 ?    ?   ?   A . n 
A 1 1522 ALA 1522 1644 ?    ?   ?   A . n 
A 1 1523 TYR 1523 1645 ?    ?   ?   A . n 
A 1 1524 GLY 1524 1646 ?    ?   ?   A . n 
A 1 1525 ARG 1525 1647 ?    ?   ?   A . n 
A 1 1526 ARG 1526 1648 ?    ?   ?   A . n 
A 1 1527 ARG 1527 1649 ?    ?   ?   A . n 
A 1 1528 GLN 1528 1650 ?    ?   ?   A . n 
A 1 1529 GLN 1529 1651 ?    ?   ?   A . n 
A 1 1530 LEU 1530 1652 ?    ?   ?   A . n 
A 1 1531 GLU 1531 1653 ?    ?   ?   A . n 
A 1 1532 TYR 1532 1654 ?    ?   ?   A . n 
A 1 1533 THR 1533 1655 ?    ?   ?   A . n 
A 1 1534 VAL 1534 1656 ?    ?   ?   A . n 
A 1 1535 GLU 1535 1657 ?    ?   ?   A . n 
A 1 1536 LEU 1536 1658 ?    ?   ?   A . n 
A 1 1537 GLU 1537 1659 ?    ?   ?   A . n 
A 1 1538 PRO 1538 1660 ?    ?   ?   A . n 
A 1 1539 GLU 1539 1661 ?    ?   ?   A . n 
A 1 1540 GLU 1540 1662 ?    ?   ?   A . n 
A 1 1541 VAL 1541 1663 ?    ?   ?   A . n 
A 1 1542 ARG 1542 1664 ?    ?   ?   A . n 
A 1 1543 LEU 1543 1665 ?    ?   ?   A . n 
A 1 1544 LEU 1544 1666 ?    ?   ?   A . n 
A 1 1545 GLN 1545 1667 ?    ?   ?   A . n 
A 1 1546 ALA 1546 1668 ?    ?   ?   A . n 
A 1 1547 HIS 1547 1669 ?    ?   ?   A . n 
A 1 1548 ASN 1548 1670 ?    ?   ?   A . n 
A 1 1549 TYR 1549 1671 ?    ?   ?   A . n 
A 1 1550 GLN 1550 1672 ?    ?   ?   A . n 
A 1 1551 ALA 1551 1673 ?    ?   ?   A . n 
A 1 1552 TYR 1552 1674 ?    ?   ?   A . n 
A 1 1553 PRO 1553 1675 ?    ?   ?   A . n 
A 1 1554 PRO 1554 1676 ?    ?   ?   A . n 
A 1 1555 LYS 1555 1677 ?    ?   ?   A . n 
A 1 1556 ASN 1556 1678 ?    ?   ?   A . n 
A 1 1557 CYS 1557 1679 ?    ?   ?   A . n 
A 1 1558 LEU 1558 1680 ?    ?   ?   A . n 
A 1 1559 LEU 1559 1681 ?    ?   ?   A . n 
A 1 1560 LEU 1560 1682 ?    ?   ?   A . n 
A 1 1561 PRO 1561 1683 ?    ?   ?   A . n 
A 1 1562 SER 1562 1684 ?    ?   ?   A . n 
A 1 1563 SER 1563 1685 ?    ?   ?   A . n 
A 1 1564 GLY 1564 1686 ?    ?   ?   A . n 
A 1 1565 GLY 1565 1687 ?    ?   ?   A . n 
A 1 1566 SER 1566 1688 ?    ?   ?   A . n 
A 1 1567 LEU 1567 1689 ?    ?   ?   A . n 
A 1 1568 LEU 1568 1690 ?    ?   ?   A . n 
A 1 1569 LYS 1569 1691 ?    ?   ?   A . n 
A 1 1570 ALA 1570 1692 ?    ?   ?   A . n 
A 1 1571 THR 1571 1693 ?    ?   ?   A . n 
A 1 1572 ASP 1572 1694 ?    ?   ?   A . n 
A 1 1573 CYS 1573 1695 ?    ?   ?   A . n 
A 1 1574 GLU 1574 1696 ?    ?   ?   A . n 
A 1 1575 GLU 1575 1697 ?    ?   ?   A . n 
A 1 1576 GLN 1576 1698 ?    ?   ?   A . n 
A 1 1577 ARG 1577 1699 ?    ?   ?   A . n 
A 1 1578 CYS 1578 1700 ?    ?   ?   A . n 
A 1 1579 LEU 1579 1701 ?    ?   ?   A . n 
A 1 1580 LEU 1580 1702 ?    ?   ?   A . n 
A 1 1581 ASN 1581 1703 ?    ?   ?   A . n 
A 1 1582 LEU 1582 1704 ?    ?   ?   A . n 
A 1 1583 PRO 1583 1705 ?    ?   ?   A . n 
A 1 1584 MET 1584 1706 ?    ?   ?   A . n 
A 1 1585 ILE 1585 1707 ?    ?   ?   A . n 
A 1 1586 THR 1586 1708 ?    ?   ?   A . n 
A 1 1587 ALA 1587 1709 ?    ?   ?   A . n 
A 1 1588 SER 1588 1710 ?    ?   ?   A . n 
A 1 1589 GLU 1589 1711 ?    ?   ?   A . n 
A 1 1590 ASP 1590 1712 ?    ?   ?   A . n 
A 1 1591 CYS 1591 1713 ?    ?   ?   A . n 
A 1 1592 PRO 1592 1714 ?    ?   ?   A . n 
A 1 1593 LEU 1593 1715 ?    ?   ?   A . n 
A 1 1594 PRO 1594 1716 ?    ?   ?   A . n 
A 1 1595 ILE 1595 1717 ?    ?   ?   A . n 
A 1 1596 PRO 1596 1718 ?    ?   ?   A . n 
A 1 1597 GLY 1597 1719 ?    ?   ?   A . n 
A 1 1598 VAL 1598 1720 ?    ?   ?   A . n 
A 1 1599 ARG 1599 1721 ?    ?   ?   A . n 
A 1 1600 TYR 1600 1722 ?    ?   ?   A . n 
A 1 1601 GLN 1601 1723 ?    ?   ?   A . n 
A 1 1602 LEU 1602 1724 ?    ?   ?   A . n 
A 1 1603 ASN 1603 1725 ?    ?   ?   A . n 
A 1 1604 LEU 1604 1726 ?    ?   ?   A . n 
A 1 1605 THR 1605 1727 ?    ?   ?   A . n 
A 1 1606 LEU 1606 1728 ?    ?   ?   A . n 
A 1 1607 ALA 1607 1729 ?    ?   ?   A . n 
A 1 1608 ARG 1608 1730 ?    ?   ?   A . n 
A 1 1609 GLY 1609 1731 ?    ?   ?   A . n 
A 1 1610 PRO 1610 1732 ?    ?   ?   A . n 
A 1 1611 GLY 1611 1733 ?    ?   ?   A . n 
A 1 1612 SER 1612 1734 ?    ?   ?   A . n 
A 1 1613 GLU 1613 1735 ?    ?   ?   A . n 
A 1 1614 GLU 1614 1736 ?    ?   ?   A . n 
A 1 1615 HIS 1615 1737 ?    ?   ?   A . n 
A 1 1616 ASP 1616 1738 ?    ?   ?   A . n 
A 1 1617 HIS 1617 1739 ?    ?   ?   A . n 
A 1 1618 GLY 1618 1740 ?    ?   ?   A . n 
A 1 1619 VAL 1619 1741 ?    ?   ?   A . n 
A 1 1620 GLU 1620 1742 ?    ?   ?   A . n 
A 1 1621 PRO 1621 1743 ?    ?   ?   A . n 
A 1 1622 LEU 1622 1744 ?    ?   ?   A . n 
A 1 1623 GLY 1623 1745 ?    ?   ?   A . n 
A 1 1624 GLN 1624 1746 ?    ?   ?   A . n 
A 1 1625 TRP 1625 1747 ?    ?   ?   A . n 
A 1 1626 LEU 1626 1748 ?    ?   ?   A . n 
A 1 1627 LEU 1627 1749 ?    ?   ?   A . n 
A 1 1628 GLY 1628 1750 ?    ?   ?   A . n 
A 1 1629 ALA 1629 1751 ?    ?   ?   A . n 
A 1 1630 GLY 1630 1752 ?    ?   ?   A . n 
A 1 1631 GLU 1631 1753 ?    ?   ?   A . n 
A 1 1632 SER 1632 1754 ?    ?   ?   A . n 
A 1 1633 LEU 1633 1755 ?    ?   ?   A . n 
A 1 1634 ASN 1634 1756 ?    ?   ?   A . n 
A 1 1635 LEU 1635 1757 ?    ?   ?   A . n 
A 1 1636 THR 1636 1758 ?    ?   ?   A . n 
A 1 1637 ASP 1637 1759 ?    ?   ?   A . n 
A 1 1638 LEU 1638 1760 ?    ?   ?   A . n 
A 1 1639 LEU 1639 1761 ?    ?   ?   A . n 
A 1 1640 PRO 1640 1762 ?    ?   ?   A . n 
A 1 1641 PHE 1641 1763 ?    ?   ?   A . n 
A 1 1642 THR 1642 1764 ?    ?   ?   A . n 
A 1 1643 ARG 1643 1765 ?    ?   ?   A . n 
A 1 1644 TYR 1644 1766 ?    ?   ?   A . n 
A 1 1645 ARG 1645 1767 ?    ?   ?   A . n 
A 1 1646 VAL 1646 1768 ?    ?   ?   A . n 
A 1 1647 SER 1647 1769 ?    ?   ?   A . n 
A 1 1648 GLY 1648 1770 ?    ?   ?   A . n 
A 1 1649 ILE 1649 1771 ?    ?   ?   A . n 
A 1 1650 LEU 1650 1772 ?    ?   ?   A . n 
A 1 1651 SER 1651 1773 ?    ?   ?   A . n 
A 1 1652 SER 1652 1774 ?    ?   ?   A . n 
A 1 1653 PHE 1653 1775 ?    ?   ?   A . n 
A 1 1654 TYR 1654 1776 ?    ?   ?   A . n 
A 1 1655 GLN 1655 1777 ?    ?   ?   A . n 
A 1 1656 LYS 1656 1778 ?    ?   ?   A . n 
A 1 1657 LYS 1657 1779 ?    ?   ?   A . n 
A 1 1658 LEU 1658 1780 ?    ?   ?   A . n 
A 1 1659 ALA 1659 1781 ?    ?   ?   A . n 
A 1 1660 LEU 1660 1782 ?    ?   ?   A . n 
A 1 1661 PRO 1661 1783 ?    ?   ?   A . n 
A 1 1662 THR 1662 1784 ?    ?   ?   A . n 
A 1 1663 LEU 1663 1785 ?    ?   ?   A . n 
A 1 1664 VAL 1664 1786 ?    ?   ?   A . n 
A 1 1665 LEU 1665 1787 ?    ?   ?   A . n 
A 1 1666 ALA 1666 1788 ?    ?   ?   A . n 
A 1 1667 PRO 1667 1789 ?    ?   ?   A . n 
A 1 1668 LEU 1668 1790 ?    ?   ?   A . n 
A 1 1669 GLU 1669 1791 ?    ?   ?   A . n 
A 1 1670 LEU 1670 1792 ?    ?   ?   A . n 
A 1 1671 LEU 1671 1793 ?    ?   ?   A . n 
A 1 1672 THR 1672 1794 ?    ?   ?   A . n 
A 1 1673 ALA 1673 1795 ?    ?   ?   A . n 
A 1 1674 SER 1674 1796 ?    ?   ?   A . n 
A 1 1675 ALA 1675 1797 ?    ?   ?   A . n 
A 1 1676 THR 1676 1798 ?    ?   ?   A . n 
A 1 1677 PRO 1677 1799 ?    ?   ?   A . n 
A 1 1678 SER 1678 1800 ?    ?   ?   A . n 
A 1 1679 PRO 1679 1801 ?    ?   ?   A . n 
A 1 1680 PRO 1680 1802 ?    ?   ?   A . n 
A 1 1681 ARG 1681 1803 ?    ?   ?   A . n 
A 1 1682 ASN 1682 1804 ?    ?   ?   A . n 
A 1 1683 PHE 1683 1805 ?    ?   ?   A . n 
A 1 1684 SER 1684 1806 ?    ?   ?   A . n 
A 1 1685 VAL 1685 1807 ?    ?   ?   A . n 
A 1 1686 ARG 1686 1808 ?    ?   ?   A . n 
A 1 1687 VAL 1687 1809 ?    ?   ?   A . n 
A 1 1688 LEU 1688 1810 ?    ?   ?   A . n 
A 1 1689 SER 1689 1811 ?    ?   ?   A . n 
A 1 1690 PRO 1690 1812 ?    ?   ?   A . n 
A 1 1691 ARG 1691 1813 ?    ?   ?   A . n 
A 1 1692 GLU 1692 1814 ?    ?   ?   A . n 
A 1 1693 LEU 1693 1815 ?    ?   ?   A . n 
A 1 1694 GLU 1694 1816 ?    ?   ?   A . n 
A 1 1695 VAL 1695 1817 ?    ?   ?   A . n 
A 1 1696 SER 1696 1818 ?    ?   ?   A . n 
A 1 1697 TRP 1697 1819 ?    ?   ?   A . n 
A 1 1698 LEU 1698 1820 ?    ?   ?   A . n 
A 1 1699 PRO 1699 1821 ?    ?   ?   A . n 
A 1 1700 PRO 1700 1822 ?    ?   ?   A . n 
A 1 1701 GLU 1701 1823 ?    ?   ?   A . n 
A 1 1702 GLN 1702 1824 ?    ?   ?   A . n 
A 1 1703 LEU 1703 1825 ?    ?   ?   A . n 
A 1 1704 ARG 1704 1826 ?    ?   ?   A . n 
A 1 1705 SER 1705 1827 ?    ?   ?   A . n 
A 1 1706 GLU 1706 1828 ?    ?   ?   A . n 
A 1 1707 SER 1707 1829 ?    ?   ?   A . n 
A 1 1708 VAL 1708 1830 ?    ?   ?   A . n 
A 1 1709 TYR 1709 1831 ?    ?   ?   A . n 
A 1 1710 TYR 1710 1832 ?    ?   ?   A . n 
A 1 1711 THR 1711 1833 ?    ?   ?   A . n 
A 1 1712 LEU 1712 1834 ?    ?   ?   A . n 
A 1 1713 HIS 1713 1835 ?    ?   ?   A . n 
A 1 1714 TRP 1714 1836 ?    ?   ?   A . n 
A 1 1715 GLN 1715 1837 ?    ?   ?   A . n 
A 1 1716 GLN 1716 1838 ?    ?   ?   A . n 
A 1 1717 GLU 1717 1839 ?    ?   ?   A . n 
A 1 1718 LEU 1718 1840 ?    ?   ?   A . n 
A 1 1719 ASP 1719 1841 ?    ?   ?   A . n 
A 1 1720 GLY 1720 1842 ?    ?   ?   A . n 
A 1 1721 GLU 1721 1843 ?    ?   ?   A . n 
A 1 1722 ASN 1722 1844 ?    ?   ?   A . n 
A 1 1723 VAL 1723 1845 ?    ?   ?   A . n 
A 1 1724 GLN 1724 1846 ?    ?   ?   A . n 
A 1 1725 ASP 1725 1847 ?    ?   ?   A . n 
A 1 1726 ARG 1726 1848 ?    ?   ?   A . n 
A 1 1727 ARG 1727 1849 ?    ?   ?   A . n 
A 1 1728 GLU 1728 1850 ?    ?   ?   A . n 
A 1 1729 TRP 1729 1851 ?    ?   ?   A . n 
A 1 1730 GLU 1730 1852 ?    ?   ?   A . n 
A 1 1731 ALA 1731 1853 ?    ?   ?   A . n 
A 1 1732 HIS 1732 1854 ?    ?   ?   A . n 
A 1 1733 GLU 1733 1855 ?    ?   ?   A . n 
A 1 1734 ARG 1734 1856 ?    ?   ?   A . n 
A 1 1735 ARG 1735 1857 ?    ?   ?   A . n 
A 1 1736 LEU 1736 1858 ?    ?   ?   A . n 
A 1 1737 GLU 1737 1859 ?    ?   ?   A . n 
A 1 1738 THR 1738 1860 ?    ?   ?   A . n 
A 1 1739 ALA 1739 1861 ?    ?   ?   A . n 
A 1 1740 GLY 1740 1862 ?    ?   ?   A . n 
A 1 1741 THR 1741 1863 ?    ?   ?   A . n 
A 1 1742 HIS 1742 1864 ?    ?   ?   A . n 
A 1 1743 ARG 1743 1865 ?    ?   ?   A . n 
A 1 1744 LEU 1744 1866 ?    ?   ?   A . n 
A 1 1745 THR 1745 1867 ?    ?   ?   A . n 
A 1 1746 GLY 1746 1868 ?    ?   ?   A . n 
A 1 1747 ILE 1747 1869 ?    ?   ?   A . n 
A 1 1748 LYS 1748 1870 ?    ?   ?   A . n 
A 1 1749 PRO 1749 1871 ?    ?   ?   A . n 
A 1 1750 GLY 1750 1872 ?    ?   ?   A . n 
A 1 1751 SER 1751 1873 ?    ?   ?   A . n 
A 1 1752 GLY 1752 1874 ?    ?   ?   A . n 
A 1 1753 TYR 1753 1875 ?    ?   ?   A . n 
A 1 1754 SER 1754 1876 ?    ?   ?   A . n 
A 1 1755 LEU 1755 1877 ?    ?   ?   A . n 
A 1 1756 TRP 1756 1878 ?    ?   ?   A . n 
A 1 1757 VAL 1757 1879 ?    ?   ?   A . n 
A 1 1758 GLN 1758 1880 ?    ?   ?   A . n 
A 1 1759 ALA 1759 1881 ?    ?   ?   A . n 
A 1 1760 HIS 1760 1882 ?    ?   ?   A . n 
A 1 1761 ALA 1761 1883 ?    ?   ?   A . n 
A 1 1762 THR 1762 1884 ?    ?   ?   A . n 
A 1 1763 PRO 1763 1885 ?    ?   ?   A . n 
A 1 1764 THR 1764 1886 ?    ?   ?   A . n 
A 1 1765 LYS 1765 1887 ?    ?   ?   A . n 
A 1 1766 SER 1766 1888 ?    ?   ?   A . n 
A 1 1767 ASN 1767 1889 ?    ?   ?   A . n 
A 1 1768 SER 1768 1890 ?    ?   ?   A . n 
A 1 1769 SER 1769 1891 ?    ?   ?   A . n 
A 1 1770 GLU 1770 1892 ?    ?   ?   A . n 
A 1 1771 ARG 1771 1893 ?    ?   ?   A . n 
A 1 1772 LEU 1772 1894 ?    ?   ?   A . n 
A 1 1773 HIS 1773 1895 ?    ?   ?   A . n 
A 1 1774 VAL 1774 1896 ?    ?   ?   A . n 
A 1 1775 ARG 1775 1897 ?    ?   ?   A . n 
A 1 1776 SER 1776 1898 ?    ?   ?   A . n 
A 1 1777 PHE 1777 1899 ?    ?   ?   A . n 
A 1 1778 ALA 1778 1900 ?    ?   ?   A . n 
A 1 1779 GLU 1779 1901 ?    ?   ?   A . n 
A 1 1780 LEU 1780 1902 ?    ?   ?   A . n 
A 1 1781 PRO 1781 1903 ?    ?   ?   A . n 
A 1 1782 GLU 1782 1904 ?    ?   ?   A . n 
A 1 1783 LEU 1783 1905 ?    ?   ?   A . n 
A 1 1784 GLN 1784 1906 ?    ?   ?   A . n 
A 1 1785 LEU 1785 1907 ?    ?   ?   A . n 
A 1 1786 LEU 1786 1908 ?    ?   ?   A . n 
A 1 1787 GLU 1787 1909 ?    ?   ?   A . n 
A 1 1788 LEU 1788 1910 ?    ?   ?   A . n 
A 1 1789 GLY 1789 1911 ?    ?   ?   A . n 
A 1 1790 PRO 1790 1912 ?    ?   ?   A . n 
A 1 1791 TYR 1791 1913 ?    ?   ?   A . n 
A 1 1792 SER 1792 1914 ?    ?   ?   A . n 
A 1 1793 LEU 1793 1915 ?    ?   ?   A . n 
A 1 1794 SER 1794 1916 ?    ?   ?   A . n 
A 1 1795 LEU 1795 1917 ?    ?   ?   A . n 
A 1 1796 THR 1796 1918 ?    ?   ?   A . n 
A 1 1797 TRP 1797 1919 ?    ?   ?   A . n 
A 1 1798 ALA 1798 1920 ?    ?   ?   A . n 
A 1 1799 GLY 1799 1921 ?    ?   ?   A . n 
A 1 1800 THR 1800 1922 ?    ?   ?   A . n 
A 1 1801 PRO 1801 1923 ?    ?   ?   A . n 
A 1 1802 ASP 1802 1924 ?    ?   ?   A . n 
A 1 1803 PRO 1803 1925 ?    ?   ?   A . n 
A 1 1804 LEU 1804 1926 ?    ?   ?   A . n 
A 1 1805 GLY 1805 1927 ?    ?   ?   A . n 
A 1 1806 SER 1806 1928 ?    ?   ?   A . n 
A 1 1807 LEU 1807 1929 ?    ?   ?   A . n 
A 1 1808 GLN 1808 1930 ?    ?   ?   A . n 
A 1 1809 LEU 1809 1931 ?    ?   ?   A . n 
A 1 1810 GLU 1810 1932 ?    ?   ?   A . n 
A 1 1811 CYS 1811 1933 ?    ?   ?   A . n 
A 1 1812 ARG 1812 1934 ?    ?   ?   A . n 
A 1 1813 SER 1813 1935 ?    ?   ?   A . n 
A 1 1814 SER 1814 1936 ?    ?   ?   A . n 
A 1 1815 ALA 1815 1937 ?    ?   ?   A . n 
A 1 1816 GLU 1816 1938 ?    ?   ?   A . n 
A 1 1817 GLN 1817 1939 ?    ?   ?   A . n 
A 1 1818 LEU 1818 1940 ?    ?   ?   A . n 
A 1 1819 ARG 1819 1941 ?    ?   ?   A . n 
A 1 1820 ARG 1820 1942 ?    ?   ?   A . n 
A 1 1821 ASN 1821 1943 ?    ?   ?   A . n 
A 1 1822 VAL 1822 1944 ?    ?   ?   A . n 
A 1 1823 ALA 1823 1945 ?    ?   ?   A . n 
A 1 1824 GLY 1824 1946 ?    ?   ?   A . n 
A 1 1825 ASN 1825 1947 ?    ?   ?   A . n 
A 1 1826 HIS 1826 1948 ?    ?   ?   A . n 
A 1 1827 THR 1827 1949 ?    ?   ?   A . n 
A 1 1828 LYS 1828 1950 ?    ?   ?   A . n 
A 1 1829 MET 1829 1951 ?    ?   ?   A . n 
A 1 1830 VAL 1830 1952 ?    ?   ?   A . n 
A 1 1831 VAL 1831 1953 ?    ?   ?   A . n 
A 1 1832 GLU 1832 1954 ?    ?   ?   A . n 
A 1 1833 PRO 1833 1955 ?    ?   ?   A . n 
A 1 1834 LEU 1834 1956 ?    ?   ?   A . n 
A 1 1835 GLN 1835 1957 ?    ?   ?   A . n 
A 1 1836 PRO 1836 1958 ?    ?   ?   A . n 
A 1 1837 ARG 1837 1959 ?    ?   ?   A . n 
A 1 1838 THR 1838 1960 ?    ?   ?   A . n 
A 1 1839 ARG 1839 1961 ?    ?   ?   A . n 
A 1 1840 TYR 1840 1962 ?    ?   ?   A . n 
A 1 1841 GLN 1841 1963 ?    ?   ?   A . n 
A 1 1842 CYS 1842 1964 ?    ?   ?   A . n 
A 1 1843 ARG 1843 1965 ?    ?   ?   A . n 
A 1 1844 LEU 1844 1966 ?    ?   ?   A . n 
A 1 1845 LEU 1845 1967 ?    ?   ?   A . n 
A 1 1846 LEU 1846 1968 ?    ?   ?   A . n 
A 1 1847 GLY 1847 1969 ?    ?   ?   A . n 
A 1 1848 TYR 1848 1970 ?    ?   ?   A . n 
A 1 1849 ALA 1849 1971 ?    ?   ?   A . n 
A 1 1850 ALA 1850 1972 ?    ?   ?   A . n 
A 1 1851 THR 1851 1973 ?    ?   ?   A . n 
A 1 1852 PRO 1852 1974 ?    ?   ?   A . n 
A 1 1853 GLY 1853 1975 ?    ?   ?   A . n 
A 1 1854 ALA 1854 1976 ?    ?   ?   A . n 
A 1 1855 PRO 1855 1977 ?    ?   ?   A . n 
A 1 1856 LEU 1856 1978 ?    ?   ?   A . n 
A 1 1857 TYR 1857 1979 ?    ?   ?   A . n 
A 1 1858 HIS 1858 1980 ?    ?   ?   A . n 
A 1 1859 GLY 1859 1981 ?    ?   ?   A . n 
A 1 1860 THR 1860 1982 ?    ?   ?   A . n 
A 1 1861 ALA 1861 1983 ?    ?   ?   A . n 
A 1 1862 GLU 1862 1984 ?    ?   ?   A . n 
A 1 1863 VAL 1863 1985 ?    ?   ?   A . n 
A 1 1864 TYR 1864 1986 ?    ?   ?   A . n 
A 1 1865 GLU 1865 1987 ?    ?   ?   A . n 
A 1 1866 THR 1866 1988 ?    ?   ?   A . n 
A 1 1867 LEU 1867 1989 ?    ?   ?   A . n 
A 1 1868 GLY 1868 1990 ?    ?   ?   A . n 
A 1 1869 ASP 1869 1991 ?    ?   ?   A . n 
A 1 1870 ALA 1870 1992 ?    ?   ?   A . n 
A 1 1871 PRO 1871 1993 ?    ?   ?   A . n 
A 1 1872 SER 1872 1994 ?    ?   ?   A . n 
A 1 1873 GLN 1873 1995 ?    ?   ?   A . n 
A 1 1874 PRO 1874 1996 ?    ?   ?   A . n 
A 1 1875 GLY 1875 1997 ?    ?   ?   A . n 
A 1 1876 LYS 1876 1998 ?    ?   ?   A . n 
A 1 1877 PRO 1877 1999 ?    ?   ?   A . n 
A 1 1878 GLN 1878 2000 ?    ?   ?   A . n 
A 1 1879 LEU 1879 2001 ?    ?   ?   A . n 
A 1 1880 GLU 1880 2002 ?    ?   ?   A . n 
A 1 1881 HIS 1881 2003 ?    ?   ?   A . n 
A 1 1882 ILE 1882 2004 ?    ?   ?   A . n 
A 1 1883 ALA 1883 2005 ?    ?   ?   A . n 
A 1 1884 GLU 1884 2006 ?    ?   ?   A . n 
A 1 1885 GLU 1885 2007 ?    ?   ?   A . n 
A 1 1886 VAL 1886 2008 ?    ?   ?   A . n 
A 1 1887 PHE 1887 2009 ?    ?   ?   A . n 
A 1 1888 ARG 1888 2010 ?    ?   ?   A . n 
A 1 1889 VAL 1889 2011 ?    ?   ?   A . n 
A 1 1890 THR 1890 2012 ?    ?   ?   A . n 
A 1 1891 TRP 1891 2013 ?    ?   ?   A . n 
A 1 1892 THR 1892 2014 ?    ?   ?   A . n 
A 1 1893 ALA 1893 2015 ?    ?   ?   A . n 
A 1 1894 ALA 1894 2016 ?    ?   ?   A . n 
A 1 1895 ARG 1895 2017 ?    ?   ?   A . n 
A 1 1896 GLY 1896 2018 ?    ?   ?   A . n 
A 1 1897 ASN 1897 2019 ?    ?   ?   A . n 
A 1 1898 GLY 1898 2020 ?    ?   ?   A . n 
A 1 1899 ALA 1899 2021 ?    ?   ?   A . n 
A 1 1900 PRO 1900 2022 ?    ?   ?   A . n 
A 1 1901 ILE 1901 2023 ?    ?   ?   A . n 
A 1 1902 ALA 1902 2024 ?    ?   ?   A . n 
A 1 1903 LEU 1903 2025 ?    ?   ?   A . n 
A 1 1904 TYR 1904 2026 ?    ?   ?   A . n 
A 1 1905 ASN 1905 2027 ?    ?   ?   A . n 
A 1 1906 LEU 1906 2028 ?    ?   ?   A . n 
A 1 1907 GLU 1907 2029 ?    ?   ?   A . n 
A 1 1908 ALA 1908 2030 ?    ?   ?   A . n 
A 1 1909 LEU 1909 2031 ?    ?   ?   A . n 
A 1 1910 GLN 1910 2032 ?    ?   ?   A . n 
A 1 1911 ALA 1911 2033 ?    ?   ?   A . n 
A 1 1912 ARG 1912 2034 ?    ?   ?   A . n 
A 1 1913 SER 1913 2035 ?    ?   ?   A . n 
A 1 1914 ASP 1914 2036 ?    ?   ?   A . n 
A 1 1915 ILE 1915 2037 ?    ?   ?   A . n 
A 1 1916 ASN 1916 2038 ?    ?   ?   A . n 
A 1 1917 SER 1917 2039 ?    ?   ?   A . n 
A 1 1918 GLY 1918 2040 ?    ?   ?   A . n 
A 1 1919 GLY 1919 2041 ?    ?   ?   A . n 
A 1 1920 SER 1920 2042 ?    ?   ?   A . n 
A 1 1921 LEU 1921 2043 ?    ?   ?   A . n 
A 1 1922 GLU 1922 2044 ?    ?   ?   A . n 
A 1 1923 GLN 1923 2045 ?    ?   ?   A . n 
A 1 1924 LEU 1924 2046 ?    ?   ?   A . n 
A 1 1925 PRO 1925 2047 ?    ?   ?   A . n 
A 1 1926 TRP 1926 2048 ?    ?   ?   A . n 
A 1 1927 ALA 1927 2049 ?    ?   ?   A . n 
A 1 1928 GLU 1928 2050 ?    ?   ?   A . n 
A 1 1929 GLU 1929 2051 ?    ?   ?   A . n 
A 1 1930 PRO 1930 2052 ?    ?   ?   A . n 
A 1 1931 VAL 1931 2053 ?    ?   ?   A . n 
A 1 1932 VAL 1932 2054 ?    ?   ?   A . n 
A 1 1933 VAL 1933 2055 ?    ?   ?   A . n 
A 1 1934 GLU 1934 2056 ?    ?   ?   A . n 
A 1 1935 ASP 1935 2057 ?    ?   ?   A . n 
A 1 1936 GLN 1936 2058 ?    ?   ?   A . n 
A 1 1937 TRP 1937 2059 ?    ?   ?   A . n 
A 1 1938 LEU 1938 2060 ?    ?   ?   A . n 
A 1 1939 ASP 1939 2061 ?    ?   ?   A . n 
A 1 1940 PHE 1940 2062 ?    ?   ?   A . n 
A 1 1941 CYS 1941 2063 ?    ?   ?   A . n 
A 1 1942 ASN 1942 2064 ?    ?   ?   A . n 
A 1 1943 THR 1943 2065 ?    ?   ?   A . n 
A 1 1944 THR 1944 2066 ?    ?   ?   A . n 
A 1 1945 GLU 1945 2067 ?    ?   ?   A . n 
A 1 1946 LEU 1946 2068 ?    ?   ?   A . n 
A 1 1947 SER 1947 2069 ?    ?   ?   A . n 
A 1 1948 CYS 1948 2070 ?    ?   ?   A . n 
A 1 1949 ILE 1949 2071 ?    ?   ?   A . n 
A 1 1950 VAL 1950 2072 ?    ?   ?   A . n 
A 1 1951 LYS 1951 2073 ?    ?   ?   A . n 
A 1 1952 SER 1952 2074 ?    ?   ?   A . n 
A 1 1953 LEU 1953 2075 ?    ?   ?   A . n 
A 1 1954 HIS 1954 2076 ?    ?   ?   A . n 
A 1 1955 SER 1955 2077 ?    ?   ?   A . n 
A 1 1956 SER 1956 2078 ?    ?   ?   A . n 
A 1 1957 ARG 1957 2079 ?    ?   ?   A . n 
A 1 1958 LEU 1958 2080 ?    ?   ?   A . n 
A 1 1959 LEU 1959 2081 ?    ?   ?   A . n 
A 1 1960 LEU 1960 2082 ?    ?   ?   A . n 
A 1 1961 PHE 1961 2083 ?    ?   ?   A . n 
A 1 1962 ARG 1962 2084 ?    ?   ?   A . n 
A 1 1963 VAL 1963 2085 ?    ?   ?   A . n 
A 1 1964 ARG 1964 2086 ?    ?   ?   A . n 
A 1 1965 ALA 1965 2087 ?    ?   ?   A . n 
A 1 1966 ARG 1966 2088 ?    ?   ?   A . n 
A 1 1967 SER 1967 2089 ?    ?   ?   A . n 
A 1 1968 LEU 1968 2090 ?    ?   ?   A . n 
A 1 1969 GLU 1969 2091 ?    ?   ?   A . n 
A 1 1970 HIS 1970 2092 ?    ?   ?   A . n 
A 1 1971 GLY 1971 2093 ?    ?   ?   A . n 
A 1 1972 TRP 1972 2094 ?    ?   ?   A . n 
A 1 1973 GLY 1973 2095 ?    ?   ?   A . n 
A 1 1974 PRO 1974 2096 ?    ?   ?   A . n 
A 1 1975 TYR 1975 2097 ?    ?   ?   A . n 
A 1 1976 SER 1976 2098 ?    ?   ?   A . n 
A 1 1977 GLU 1977 2099 ?    ?   ?   A . n 
A 1 1978 GLU 1978 2100 ?    ?   ?   A . n 
A 1 1979 SER 1979 2101 ?    ?   ?   A . n 
A 1 1980 GLU 1980 2102 ?    ?   ?   A . n 
A 1 1981 ARG 1981 2103 ?    ?   ?   A . n 
A 1 1982 VAL 1982 2104 ?    ?   ?   A . n 
A 1 1983 ALA 1983 2105 ?    ?   ?   A . n 
A 1 1984 GLU 1984 2106 ?    ?   ?   A . n 
A 1 1985 PRO 1985 2107 ?    ?   ?   A . n 
A 1 1986 PHE 1986 2108 ?    ?   ?   A . n 
A 1 1987 VAL 1987 2109 ?    ?   ?   A . n 
A 1 1988 SER 1988 2110 ?    ?   ?   A . n 
A 1 1989 HIS 1989 2111 ?    ?   ?   A . n 
A 1 1990 HIS 1990 2112 ?    ?   ?   A . n 
A 1 1991 HIS 1991 2113 ?    ?   ?   A . n 
A 1 1992 HIS 1992 2114 ?    ?   ?   A . n 
A 1 1993 HIS 1993 2115 ?    ?   ?   A . n 
A 1 1994 HIS 1994 2116 ?    ?   ?   A . n 
A 1 1995 TRP 1995 2117 ?    ?   ?   A . n 
A 1 1996 SER 1996 2118 ?    ?   ?   A . n 
A 1 1997 HIS 1997 2119 ?    ?   ?   A . n 
A 1 1998 PRO 1998 2120 ?    ?   ?   A . n 
A 1 1999 GLN 1999 2121 ?    ?   ?   A . n 
A 1 2000 PHE 2000 2122 ?    ?   ?   A . n 
A 1 2001 GLU 2001 2123 ?    ?   ?   A . n 
A 1 2002 LYS 2002 2124 ?    ?   ?   A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
B 2 NAG 1 B NAG 1 A NAG 4289 n 
B 2 NAG 2 B NAG 2 A NAG 4290 n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        NAG 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   NAG 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C 3 NAG 1 2601 4288 NAG NAG A . 
D 3 NAG 1 2602 4291 NAG NAG A . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A GLU 339  ? CG  ? A GLU 217  CG  
2  1 Y 1 A GLU 339  ? CD  ? A GLU 217  CD  
3  1 Y 1 A GLU 339  ? OE1 ? A GLU 217  OE1 
4  1 Y 1 A GLU 339  ? OE2 ? A GLU 217  OE2 
5  1 Y 1 A HIS 340  ? CG  ? A HIS 218  CG  
6  1 Y 1 A HIS 340  ? ND1 ? A HIS 218  ND1 
7  1 Y 1 A HIS 340  ? CD2 ? A HIS 218  CD2 
8  1 Y 1 A HIS 340  ? CE1 ? A HIS 218  CE1 
9  1 Y 1 A HIS 340  ? NE2 ? A HIS 218  NE2 
10 1 Y 1 A ARG 417  ? CG  ? A ARG 295  CG  
11 1 Y 1 A ARG 417  ? CD  ? A ARG 295  CD  
12 1 Y 1 A ARG 417  ? NE  ? A ARG 295  NE  
13 1 Y 1 A ARG 417  ? CZ  ? A ARG 295  CZ  
14 1 Y 1 A ARG 417  ? NH1 ? A ARG 295  NH1 
15 1 Y 1 A ARG 417  ? NH2 ? A ARG 295  NH2 
16 1 Y 1 A ASN 481  ? CG  ? A ASN 359  CG  
17 1 Y 1 A ASN 481  ? OD1 ? A ASN 359  OD1 
18 1 Y 1 A ASN 481  ? ND2 ? A ASN 359  ND2 
19 1 Y 1 A PHE 1129 ? CG  ? A PHE 1007 CG  
20 1 Y 1 A PHE 1129 ? CD1 ? A PHE 1007 CD1 
21 1 Y 1 A PHE 1129 ? CD2 ? A PHE 1007 CD2 
22 1 Y 1 A PHE 1129 ? CE1 ? A PHE 1007 CE1 
23 1 Y 1 A PHE 1129 ? CE2 ? A PHE 1007 CE2 
24 1 Y 1 A PHE 1129 ? CZ  ? A PHE 1007 CZ  
25 1 Y 1 A LEU 1208 ? CG  ? A LEU 1086 CG  
26 1 Y 1 A LEU 1208 ? CD1 ? A LEU 1086 CD1 
27 1 Y 1 A LEU 1208 ? CD2 ? A LEU 1086 CD2 
28 1 Y 1 A ASP 1210 ? CG  ? A ASP 1088 CG  
29 1 Y 1 A ASP 1210 ? OD1 ? A ASP 1088 OD1 
30 1 Y 1 A ASP 1210 ? OD2 ? A ASP 1088 OD2 
31 1 Y 1 A HIS 1212 ? CG  ? A HIS 1090 CG  
32 1 Y 1 A HIS 1212 ? ND1 ? A HIS 1090 ND1 
33 1 Y 1 A HIS 1212 ? CD2 ? A HIS 1090 CD2 
34 1 Y 1 A HIS 1212 ? CE1 ? A HIS 1090 CE1 
35 1 Y 1 A HIS 1212 ? NE2 ? A HIS 1090 NE2 
36 1 Y 1 A TRP 1213 ? CG  ? A TRP 1091 CG  
37 1 Y 1 A TRP 1213 ? CD1 ? A TRP 1091 CD1 
38 1 Y 1 A TRP 1213 ? CD2 ? A TRP 1091 CD2 
39 1 Y 1 A TRP 1213 ? NE1 ? A TRP 1091 NE1 
40 1 Y 1 A TRP 1213 ? CE2 ? A TRP 1091 CE2 
41 1 Y 1 A TRP 1213 ? CE3 ? A TRP 1091 CE3 
42 1 Y 1 A TRP 1213 ? CZ2 ? A TRP 1091 CZ2 
43 1 Y 1 A TRP 1213 ? CZ3 ? A TRP 1091 CZ3 
44 1 Y 1 A TRP 1213 ? CH2 ? A TRP 1091 CH2 
45 1 Y 1 A ASP 1214 ? CG  ? A ASP 1092 CG  
46 1 Y 1 A ASP 1214 ? OD1 ? A ASP 1092 OD1 
47 1 Y 1 A ASP 1214 ? OD2 ? A ASP 1092 OD2 
48 1 Y 1 A ARG 1254 ? CG  ? A ARG 1132 CG  
49 1 Y 1 A ARG 1254 ? CD  ? A ARG 1132 CD  
50 1 Y 1 A ARG 1254 ? NE  ? A ARG 1132 NE  
51 1 Y 1 A ARG 1254 ? CZ  ? A ARG 1132 CZ  
52 1 Y 1 A ARG 1254 ? NH1 ? A ARG 1132 NH1 
53 1 Y 1 A ARG 1254 ? NH2 ? A ARG 1132 NH2 
54 1 Y 1 A THR 1256 ? OG1 ? A THR 1134 OG1 
55 1 Y 1 A THR 1256 ? CG2 ? A THR 1134 CG2 
56 1 Y 1 A GLN 1257 ? CG  ? A GLN 1135 CG  
57 1 Y 1 A GLN 1257 ? CD  ? A GLN 1135 CD  
58 1 Y 1 A GLN 1257 ? OE1 ? A GLN 1135 OE1 
59 1 Y 1 A GLN 1257 ? NE2 ? A GLN 1135 NE2 
60 1 Y 1 A GLN 1260 ? CG  ? A GLN 1138 CG  
61 1 Y 1 A GLN 1260 ? CD  ? A GLN 1138 CD  
62 1 Y 1 A GLN 1260 ? OE1 ? A GLN 1138 OE1 
63 1 Y 1 A GLN 1260 ? NE2 ? A GLN 1138 NE2 
64 1 Y 1 A GLN 1262 ? CG  ? A GLN 1140 CG  
65 1 Y 1 A GLN 1262 ? CD  ? A GLN 1140 CD  
66 1 Y 1 A GLN 1262 ? OE1 ? A GLN 1140 OE1 
67 1 Y 1 A GLN 1262 ? NE2 ? A GLN 1140 NE2 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BFP 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BFP 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BFP 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.entry_id                                 9BFP 
_refine.pdbx_diffrn_id                           ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.ls_d_res_low                             ? 
_refine.ls_d_res_high                            . 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_restraints                     ? 
_refine.occupancy_min                            ? 
_refine.occupancy_max                            ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.B_iso_mean                               ? 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_ksol                 ? 
_refine.solvent_model_param_bsol                 ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.details                                  ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.overall_SU_ML                            ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.006 ? 8488  ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 1.169 ? 11551 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 7.092 ? 1213  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.063 ? 1252  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.010 ? 1505  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BFP 
_struct.title                        'Cryo-EM structure of Sevenless extracellular domain (monomer)' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BFP 
_struct_keywords.text            
'sevenless, receptor tyrosine kinase, RTK, drosophila, eye development, vision, photoreceptor, ROS1, SIGNALING PROTEIN' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
D N N 3 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    7LESS_DROME 
_struct_ref.pdbx_db_accession          P13368 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;DVCRSHNYTVHQSPEPVSKDQMRLLRPKLDSDVVEKVAIWHKHAAAAPPSIVEGIAISSRPQSTMAHHPDDRDRDRDPSE
EQHGVDERMVLERVTRDCVQRCIVEEDLFLDEFGIQCEKADNGEKCYKTRCTKGCAQWYRALKELESCQEACLSLQFYPY
DMPCIGACEMAQRDYWHLQRLAISHLVERTQPQLERAPRADGQSTPLTIRWAMHFPEHYLASRPFNIQYQFVDHHGEELD
LEQEDQDASGETGSSAWFNLADYDCDEYYVCEILEALIPYTQYRFRFELPFGENRDEVLYSPATPAYQTPPEGAPISAPV
IEHLMGLDDSHLAVHWHPGRFTNGPIEGYRLRLSSSEGNATSEQLVPAGRGSYIFSQLQAGTNYTLALSMINKQGEGPVA
KGFVQTHSARNEKPAKDLTESVLLVGRRAVMWQSLEPAGENSMIYQSQEELADIAWSKREQQLWLLNVHGELRSLKFESG
QMVSPAQQLKLDLGNISSGRWVPRRLSFDWLHHRLYFAMESPERNQSSFQIISTDLLGESAQKVGESFDLPVEQLEVDAL
NGWIFWRNEESLWRQDLHGRMIHRLLRIRQPGWFLVQPQHFIIHLMLPQEGKFLEISYDGGFKHPLPLPPPSNGAGNGPA
SSHWQSFALLGRSLLLPDSGQLILVEQQGQAASPSASWPLKNLPDCWAVILLVPESQPLTSAGGKPHSLKALLGAQAAKI
SWKEPERNPYQSADAARSWSYELEVLDVASQSAFSIRNIRGPIFGLQRLQPDNLYQLRVRAINVDGEPGEWTEPLAARTW
PLGPHRLRWASRQGSVIHTNELGEGLEVQQEQLERLPGPMTMVNESVGYYVTGDGLLHCINLVHSQWGCPISEPLQHVGS
VTYDWRGGRVYWTDLARNCVVRMDPWSGSRELLPVFEANFLALDPRQGHLYYATSSQLSRHGSTPDEAVTYYRVNGLEGS
IASFVLDTQQDQLFWLVKGSGALRLYRAPLTAGGDSLQMIQQIKGVFQAVPDSLQLLRPLGALLWLERSGRRARLVRLAA
PLDVMELPTPDQASPASALQLLDPQPLPPRDEGVIPMTVLPDSVRLDDGHWDDFHVRWQPSTSGGNHSVSYRLLLEFGQR
LQTLDLSTPFARLTQLPQAQLQLKISITPRTAWRSGDTTRVQLTTPPVAPSQPRRLRVFVERLATALQEANVSAVLRWDA
PEQGQEAPMQALEYHISCWVGSELHEELRLNQSALEARVEHLQPDQTYHFQVEARVAATGAAAGAASHALHVAPEVQAVP
RVLYANAEFIGELDLDTRNRRRLVHTASPVEHLVGIEGEQRLLWVNEHVELLTHVPGSAPAKLARMRAEVLALAVDWIQR
IVYWAELDATAPQAAIIYRLDLCNFEGKILQGERVWSTPRGRLLKDLVALPQAQSLIWLEYEQGSPRNGSLRGRNLTDGS
ELEWATVQPLIRLHAGSLEPGSETLNLVDNQGKLCVYDVARQLCTASALRAQLNLLGEDSIAGQLAQDSGYLYAVKNWSI
RAYGRRRQQLEYTVELEPEEVRLLQAHNYQAYPPKNCLLLPSSGGSLLKATDCEEQRCLLNLPMITASEDCPLPIPGVRY
QLNLTLARGPGSEEHDHGVEPLGQWLLGAGESLNLTDLLPFTRYRVSGILSSFYQKKLALPTLVLAPLELLTASATPSPP
RNFSVRVLSPRELEVSWLPPEQLRSESVYYTLHWQQELDGENVQDRREWEAHERRLETAGTHRLTGIKPGSGYSLWVQAH
ATPTKSNSSERLHVRSFAELPELQLLELGPYSLSLTWAGTPDPLGSLQLECRSSAEQLRRNVAGNHTKMVVEPLQPRTRY
QCRLLLGYAATPGAPLYHGTAEVYETLGDAPSQPGKPQLEHIAEEVFRVTWTAARGNGAPIALYNLEALQARSDIRRRRR
RRRRNSGGSLEQLPWAEEPVVVEDQWLDFCNTTELSCIVKSLHSSRLLLFRVRARSLEHGWGPYSEESERVAEPFVS
;
_struct_ref.pdbx_align_begin           123 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9BFP 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1988 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P13368 
_struct_ref_seq.db_align_beg                  123 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  2119 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       123 
_struct_ref_seq.pdbx_auth_seq_align_end       2110 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BFP ?   A ?    ? UNP P13368 ARG 2038 deletion         ?    1  
1 9BFP ?   A ?    ? UNP P13368 ARG 2039 deletion         ?    2  
1 9BFP ?   A ?    ? UNP P13368 ARG 2040 deletion         ?    3  
1 9BFP ?   A ?    ? UNP P13368 ARG 2041 deletion         ?    4  
1 9BFP ?   A ?    ? UNP P13368 ARG 2042 deletion         ?    5  
1 9BFP ?   A ?    ? UNP P13368 ARG 2043 deletion         ?    6  
1 9BFP ?   A ?    ? UNP P13368 ARG 2044 deletion         ?    7  
1 9BFP ?   A ?    ? UNP P13368 ARG 2045 deletion         ?    8  
1 9BFP ?   A ?    ? UNP P13368 ARG 2046 deletion         ?    9  
1 9BFP HIS A 1989 ? UNP P13368 ?   ?    'expression tag' 2111 10 
1 9BFP HIS A 1990 ? UNP P13368 ?   ?    'expression tag' 2112 11 
1 9BFP HIS A 1991 ? UNP P13368 ?   ?    'expression tag' 2113 12 
1 9BFP HIS A 1992 ? UNP P13368 ?   ?    'expression tag' 2114 13 
1 9BFP HIS A 1993 ? UNP P13368 ?   ?    'expression tag' 2115 14 
1 9BFP HIS A 1994 ? UNP P13368 ?   ?    'expression tag' 2116 15 
1 9BFP TRP A 1995 ? UNP P13368 ?   ?    'expression tag' 2117 16 
1 9BFP SER A 1996 ? UNP P13368 ?   ?    'expression tag' 2118 17 
1 9BFP HIS A 1997 ? UNP P13368 ?   ?    'expression tag' 2119 18 
1 9BFP PRO A 1998 ? UNP P13368 ?   ?    'expression tag' 2120 19 
1 9BFP GLN A 1999 ? UNP P13368 ?   ?    'expression tag' 2121 20 
1 9BFP PHE A 2000 ? UNP P13368 ?   ?    'expression tag' 2122 21 
1 9BFP GLU A 2001 ? UNP P13368 ?   ?    'expression tag' 2123 22 
1 9BFP LYS A 2002 ? UNP P13368 ?   ?    'expression tag' 2124 23 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1 AA1 GLY A 84   ? GLU A 105  ? GLY A 206  GLU A 227  1 ? 22 
HELX_P HELX_P2 AA2 CYS A 126  ? CYS A 135  ? CYS A 248  CYS A 257  1 ? 10 
HELX_P HELX_P3 AA3 TYR A 139  ? GLU A 144  ? TYR A 261  GLU A 266  1 ? 6  
HELX_P HELX_P4 AA4 SER A 147  ? CYS A 152  ? SER A 269  CYS A 274  1 ? 6  
HELX_P HELX_P5 AA5 ASP A 161  ? THR A 190  ? ASP A 283  THR A 312  1 ? 30 
HELX_P HELX_P6 AA6 ASN A 294  ? VAL A 298  ? ASN A 416  VAL A 420  5 ? 5  
HELX_P HELX_P7 AA7 THR A 944  ? ALA A 948  ? THR A 1066 ALA A 1070 5 ? 5  
HELX_P HELX_P8 AA8 PRO A 1050 ? SER A 1054 ? PRO A 1172 SER A 1176 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 98   SG  ? ? ? 1_555 A CYS 135 SG ? ? A CYS 220  A CYS 257  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf2 disulf ?    ? A CYS 102  SG  ? ? ? 1_555 A CYS 131 SG ? ? A CYS 224  A CYS 253  1_555 ? ? ? ? ? ? ? 2.024 ? ? 
disulf3 disulf ?    ? A CYS 117  SG  ? ? ? 1_555 A CYS 126 SG ? ? A CYS 239  A CYS 248  1_555 ? ? ? ? ? ? ? 2.030 ? ? 
disulf4 disulf ?    ? A CYS 148  SG  ? ? ? 1_555 A CYS 168 SG ? ? A CYS 270  A CYS 290  1_555 ? ? ? ? ? ? ? 2.034 ? ? 
disulf5 disulf ?    ? A CYS 152  SG  ? ? ? 1_555 A CYS 164 SG ? ? A CYS 274  A CYS 286  1_555 ? ? ? ? ? ? ? 2.031 ? ? 
disulf6 disulf ?    ? A CYS 265  SG  ? ? ? 1_555 A CYS 271 SG ? ? A CYS 387  A CYS 393  1_555 ? ? ? ? ? ? ? 2.026 ? ? 
disulf7 disulf ?    ? A CYS 859  SG  ? ? ? 1_555 A CYS 869 SG ? ? A CYS 981  A CYS 991  1_555 ? ? ? ? ? ? ? 2.028 ? ? 
covale1 covale one  ? A ASN 383  ND2 ? ? ? 1_555 C NAG .   C1 ? ? A ASN 505  A NAG 2601 1_555 ? ? ? ? ? ? ? 1.451 ? 
N-Glycosylation 
covale2 covale one  ? A ASN 844  ND2 ? ? ? 1_555 B NAG .   C1 ? ? A ASN 966  B NAG 1    1_555 ? ? ? ? ? ? ? 1.463 ? 
N-Glycosylation 
covale3 covale one  ? A ASN 1106 ND2 ? ? ? 1_555 D NAG .   C1 ? ? A ASN 1228 A NAG 2602 1_555 ? ? ? ? ? ? ? 1.443 ? 
N-Glycosylation 
covale4 covale both ? B NAG .    O4  ? ? ? 1_555 B NAG .   C1 ? ? B NAG 1    B NAG 2    1_555 ? ? ? ? ? ? ? 1.442 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1  NAG B .   ? ASN A 844  ? NAG B 1    ? 1_555 ASN A 966  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
2  NAG C .   ? ASN A 383  ? NAG A 2601 ? 1_555 ASN A 505  ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
3  NAG D .   ? ASN A 1106 ? NAG A 2602 ? 1_555 ASN A 1228 ? 1_555 C1 ND2 ASN 1 NAG N-Glycosylation Carbohydrate       
4  CYS A 98  ? CYS A 135  ? CYS A 220  ? 1_555 CYS A 257  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
5  CYS A 102 ? CYS A 131  ? CYS A 224  ? 1_555 CYS A 253  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
6  CYS A 117 ? CYS A 126  ? CYS A 239  ? 1_555 CYS A 248  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
7  CYS A 148 ? CYS A 168  ? CYS A 270  ? 1_555 CYS A 290  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
8  CYS A 152 ? CYS A 164  ? CYS A 274  ? 1_555 CYS A 286  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
9  CYS A 265 ? CYS A 271  ? CYS A 387  ? 1_555 CYS A 393  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
10 CYS A 859 ? CYS A 869  ? CYS A 981  ? 1_555 CYS A 991  ? 1_555 SG SG  .   . .   None            'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          TYR 
_struct_mon_prot_cis.label_seq_id           158 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           TYR 
_struct_mon_prot_cis.auth_seq_id            280 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    159 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     281 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       0.83 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 3 ? 
AA5 ? 4 ? 
AA6 ? 4 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 4 ? 
AB3 ? 4 ? 
AB4 ? 3 ? 
AB5 ? 4 ? 
AB6 ? 4 ? 
AB7 ? 3 ? 
AB8 ? 4 ? 
AB9 ? 4 ? 
AC1 ? 4 ? 
AC2 ? 4 ? 
AC3 ? 3 ? 
AC4 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA3 1 2 ? anti-parallel 
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA5 1 2 ? anti-parallel 
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? anti-parallel 
AA6 3 4 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? anti-parallel 
AA9 3 4 ? anti-parallel 
AB1 1 2 ? anti-parallel 
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? anti-parallel 
AB3 1 2 ? anti-parallel 
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
AB6 1 2 ? anti-parallel 
AB6 2 3 ? anti-parallel 
AB6 3 4 ? anti-parallel 
AB7 1 2 ? anti-parallel 
AB7 2 3 ? anti-parallel 
AB8 1 2 ? anti-parallel 
AB8 2 3 ? anti-parallel 
AB8 3 4 ? anti-parallel 
AB9 1 2 ? anti-parallel 
AB9 2 3 ? anti-parallel 
AB9 3 4 ? anti-parallel 
AC1 1 2 ? anti-parallel 
AC1 2 3 ? anti-parallel 
AC1 3 4 ? anti-parallel 
AC2 1 2 ? anti-parallel 
AC2 2 3 ? anti-parallel 
AC2 3 4 ? anti-parallel 
AC3 1 2 ? anti-parallel 
AC3 2 3 ? anti-parallel 
AC4 1 2 ? anti-parallel 
AC4 2 3 ? anti-parallel 
AC4 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 193  ? GLU A 195  ? GLN A 315  GLU A 317  
AA1 2 LEU A 207  ? ARG A 210  ? LEU A 329  ARG A 332  
AA1 3 VAL A 270  ? ILE A 273  ? VAL A 392  ILE A 395  
AA1 4 TYR A 263  ? CYS A 265  ? TYR A 385  CYS A 387  
AA2 1 PHE A 258  ? ASN A 259  ? PHE A 380  ASN A 381  
AA2 2 ASN A 226  ? PHE A 231  ? ASN A 348  PHE A 353  
AA2 3 GLN A 282  ? LEU A 289  ? GLN A 404  LEU A 411  
AA2 4 LEU A 299  ? TYR A 300  ? LEU A 421  TYR A 422  
AA3 1 PHE A 258  ? ASN A 259  ? PHE A 380  ASN A 381  
AA3 2 ASN A 226  ? PHE A 231  ? ASN A 348  PHE A 353  
AA3 3 GLN A 282  ? LEU A 289  ? GLN A 404  LEU A 411  
AA3 4 TYR A 307  ? GLN A 308  ? TYR A 429  GLN A 430  
AA4 1 VAL A 320  ? ASP A 328  ? VAL A 442  ASP A 450  
AA4 2 HIS A 331  ? HIS A 337  ? HIS A 453  HIS A 459  
AA4 3 SER A 372  ? PHE A 375  ? SER A 494  PHE A 497  
AA5 1 SER A 362  ? VAL A 366  ? SER A 484  VAL A 488  
AA5 2 GLY A 348  ? SER A 355  ? GLY A 470  SER A 477  
AA5 3 ASN A 383  ? ILE A 391  ? ASN A 505  ILE A 513  
AA5 4 ALA A 400  ? GLN A 405  ? ALA A 522  GLN A 527  
AA6 1 ASN A 441  ? GLN A 446  ? ASN A 563  GLN A 568  
AA6 2 ALA A 429  ? SER A 434  ? ALA A 551  SER A 556  
AA6 3 SER A 421  ? VAL A 425  ? SER A 543  VAL A 547  
AA6 4 ALA A 688  ? LEU A 691  ? ALA A 810  LEU A 813  
AA7 1 LEU A 451  ? ILE A 454  ? LEU A 573  ILE A 576  
AA7 2 LEU A 465  ? ASN A 467  ? LEU A 587  ASN A 589  
AA7 3 LEU A 472  ? GLU A 478  ? LEU A 594  GLU A 600  
AA7 4 GLN A 481  ? GLN A 488  ? GLN A 603  GLN A 610  
AA8 1 VAL A 502  ? ASP A 509  ? VAL A 624  ASP A 631  
AA8 2 ARG A 514  ? GLU A 520  ? ARG A 636  GLU A 642  
AA8 3 PHE A 529  ? GLN A 530  ? PHE A 651  GLN A 652  
AA9 1 VAL A 502  ? ASP A 509  ? VAL A 624  ASP A 631  
AA9 2 ARG A 514  ? GLU A 520  ? ARG A 636  GLU A 642  
AA9 3 ILE A 532  ? ASP A 535  ? ILE A 654  ASP A 657  
AA9 4 GLN A 542  ? LYS A 543  ? GLN A 664  LYS A 665  
AB1 1 GLN A 554  ? ASP A 558  ? GLN A 676  ASP A 680  
AB1 2 TRP A 563  ? ARG A 567  ? TRP A 685  ARG A 689  
AB1 3 SER A 571  ? ASP A 576  ? SER A 693  ASP A 698  
AB1 4 HIS A 583  ? ARG A 587  ? HIS A 705  ARG A 709  
AB2 1 PHE A 594  ? GLN A 597  ? PHE A 716  GLN A 719  
AB2 2 ILE A 602  ? LEU A 607  ? ILE A 724  LEU A 729  
AB2 3 LYS A 612  ? SER A 617  ? LYS A 734  SER A 739  
AB2 4 PRO A 625  ? LEU A 626  ? PRO A 747  LEU A 748  
AB3 1 ALA A 648  ? LEU A 650  ? ALA A 770  LEU A 772  
AB3 2 SER A 653  ? PRO A 657  ? SER A 775  PRO A 779  
AB3 3 GLN A 661  ? VAL A 665  ? GLN A 783  VAL A 787  
AB3 4 ALA A 676  ? PRO A 679  ? ALA A 798  PRO A 801  
AB4 1 LYS A 710  ? LEU A 713  ? LYS A 832  LEU A 835  
AB4 2 ALA A 718  ? SER A 721  ? ALA A 840  SER A 843  
AB4 3 ILE A 763  ? LEU A 766  ? ILE A 885  LEU A 888  
AB5 1 ALA A 753  ? ILE A 759  ? ALA A 875  ILE A 881  
AB5 2 SER A 740  ? ASP A 747  ? SER A 862  ASP A 869  
AB5 3 LEU A 774  ? ILE A 782  ? LEU A 896  ILE A 904  
AB5 4 LEU A 795  ? ARG A 798  ? LEU A 917  ARG A 920  
AB6 1 GLU A 827  ? GLN A 832  ? GLU A 949  GLN A 954  
AB6 2 SER A 815  ? THR A 819  ? SER A 937  THR A 941  
AB6 3 LEU A 807  ? SER A 811  ? LEU A 929  SER A 933  
AB6 4 ALA A 1056 ? LEU A 1061 ? ALA A 1178 LEU A 1183 
AB7 1 THR A 841  ? MET A 842  ? THR A 963  MET A 964  
AB7 2 VAL A 847  ? VAL A 851  ? VAL A 969  VAL A 973  
AB7 3 LEU A 857  ? ASN A 861  ? LEU A 979  ASN A 983  
AB8 1 VAL A 878  ? ASP A 884  ? VAL A 1000 ASP A 1006 
AB8 2 ARG A 889  ? ASP A 894  ? ARG A 1011 ASP A 1016 
AB8 3 CYS A 899  ? MET A 903  ? CYS A 1021 MET A 1025 
AB8 4 ARG A 910  ? LEU A 913  ? ARG A 1032 LEU A 1035 
AB9 1 PHE A 920  ? LEU A 923  ? PHE A 1042 LEU A 1045 
AB9 2 LEU A 930  ? ALA A 933  ? LEU A 1052 ALA A 1055 
AB9 3 GLN A 937  ? HIS A 941  ? GLN A 1059 HIS A 1063 
AB9 4 THR A 950  ? ARG A 953  ? THR A 1072 ARG A 1075 
AC1 1 GLY A 959  ? ASP A 967  ? GLY A 1081 ASP A 1089 
AC1 2 GLN A 972  ? GLY A 979  ? GLN A 1094 GLY A 1101 
AC1 3 ALA A 982  ? PRO A 989  ? ALA A 1104 PRO A 1111 
AC1 4 GLN A 998  ? LYS A 1004 ? GLN A 1120 LYS A 1126 
AC2 1 GLN A 1015 ? LEU A 1017 ? GLN A 1137 LEU A 1139 
AC2 2 ALA A 1022 ? LEU A 1026 ? ALA A 1144 LEU A 1148 
AC2 3 ARG A 1032 ? ARG A 1037 ? ARG A 1154 ARG A 1159 
AC2 4 VAL A 1044 ? PRO A 1048 ? VAL A 1166 PRO A 1170 
AC3 1 ARG A 1085 ? ASP A 1087 ? ARG A 1207 ASP A 1209 
AC3 2 PHE A 1094 ? ARG A 1097 ? PHE A 1216 ARG A 1219 
AC3 3 PHE A 1130 ? LEU A 1133 ? PHE A 1252 LEU A 1255 
AC4 1 LEU A 1121 ? LEU A 1126 ? LEU A 1243 LEU A 1248 
AC4 2 SER A 1110 ? GLU A 1116 ? SER A 1232 GLU A 1238 
AC4 3 GLN A 1142 ? ARG A 1150 ? GLN A 1264 ARG A 1272 
AC4 4 THR A 1159 ? THR A 1164 ? THR A 1281 THR A 1286 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N GLN A 193  ? N GLN A 315  O ARG A 210  ? O ARG A 332  
AA1 2 3 N LEU A 207  ? N LEU A 329  O ILE A 273  ? O ILE A 395  
AA1 3 4 O GLU A 272  ? O GLU A 394  N ASP A 264  ? N ASP A 386  
AA2 1 2 O PHE A 258  ? O PHE A 380  N TYR A 229  ? N TYR A 351  
AA2 2 3 N ASN A 226  ? N ASN A 348  O GLU A 288  ? O GLU A 410  
AA2 3 4 N LEU A 289  ? N LEU A 411  O LEU A 299  ? O LEU A 421  
AA3 1 2 O PHE A 258  ? O PHE A 380  N TYR A 229  ? N TYR A 351  
AA3 2 3 N ASN A 226  ? N ASN A 348  O GLU A 288  ? O GLU A 410  
AA3 3 4 N TYR A 283  ? N TYR A 405  O TYR A 307  ? O TYR A 429  
AA4 1 2 N MET A 325  ? N MET A 447  O ALA A 333  ? O ALA A 455  
AA4 2 3 N LEU A 332  ? N LEU A 454  O PHE A 375  ? O PHE A 497  
AA5 1 2 O VAL A 366  ? O VAL A 488  N TYR A 349  ? N TYR A 471  
AA5 2 3 N SER A 354  ? N SER A 476  O THR A 385  ? O THR A 507  
AA5 3 4 N LEU A 388  ? N LEU A 510  O ALA A 400  ? O ALA A 522  
AA6 1 2 O SER A 442  ? O SER A 564  N TRP A 432  ? N TRP A 554  
AA6 2 3 O MET A 431  ? O MET A 553  N LEU A 424  ? N LEU A 546  
AA6 3 4 N VAL A 425  ? N VAL A 547  O ALA A 688  ? O ALA A 810  
AA7 1 2 N ALA A 452  ? N ALA A 574  O LEU A 466  ? O LEU A 588  
AA7 2 3 N LEU A 465  ? N LEU A 587  O ARG A 473  ? O ARG A 595  
AA7 3 4 N SER A 474  ? N SER A 596  O GLN A 487  ? O GLN A 609  
AA8 1 2 N ARG A 504  ? N ARG A 626  O ALA A 518  ? O ALA A 640  
AA8 2 3 N MET A 519  ? N MET A 641  O GLN A 530  ? O GLN A 652  
AA9 1 2 N ARG A 504  ? N ARG A 626  O ALA A 518  ? O ALA A 640  
AA9 2 3 N LEU A 515  ? N LEU A 637  O THR A 534  ? O THR A 656  
AA9 3 4 N SER A 533  ? N SER A 655  O GLN A 542  ? O GLN A 664  
AB1 1 2 N GLU A 556  ? N GLU A 678  O PHE A 565  ? O PHE A 687  
AB1 2 3 N ILE A 564  ? N ILE A 686  O GLN A 575  ? O GLN A 697  
AB1 3 4 N ARG A 574  ? N ARG A 696  O HIS A 583  ? O HIS A 705  
AB2 1 2 N LEU A 595  ? N LEU A 717  O HIS A 604  ? O HIS A 726  
AB2 2 3 N ILE A 603  ? N ILE A 725  O ILE A 616  ? O ILE A 738  
AB2 3 4 N PHE A 613  ? N PHE A 735  O LEU A 626  ? O LEU A 748  
AB3 1 2 N ALA A 648  ? N ALA A 770  O LEU A 655  ? O LEU A 777  
AB3 2 3 N LEU A 654  ? N LEU A 776  O VAL A 665  ? O VAL A 787  
AB3 3 4 N LEU A 662  ? N LEU A 784  O TRP A 678  ? O TRP A 800  
AB4 1 2 N LEU A 712  ? N LEU A 834  O LYS A 719  ? O LYS A 841  
AB4 2 3 N ILE A 720  ? N ILE A 842  O PHE A 764  ? O PHE A 886  
AB5 1 2 O ILE A 756  ? O ILE A 878  N LEU A 743  ? N LEU A 865  
AB5 2 3 N SER A 740  ? N SER A 862  O ILE A 782  ? O ILE A 904  
AB5 3 4 N TYR A 775  ? N TYR A 897  O ALA A 797  ? O ALA A 919  
AB6 1 2 O GLN A 829  ? O GLN A 951  N VAL A 816  ? N VAL A 938  
AB6 2 3 O SER A 815  ? O SER A 937  N SER A 811  ? N SER A 933  
AB6 3 4 N ARG A 808  ? N ARG A 930  O GLN A 1060 ? O GLN A 1182 
AB7 1 2 N THR A 841  ? N THR A 963  O TYR A 849  ? O TYR A 971  
AB7 2 3 N TYR A 850  ? N TYR A 972  O HIS A 858  ? O HIS A 980  
AB8 1 2 N THR A 882  ? N THR A 1004 O TYR A 891  ? O TYR A 1013 
AB8 2 3 N VAL A 890  ? N VAL A 1012 O MET A 903  ? O MET A 1025 
AB8 3 4 N ARG A 902  ? N ARG A 1024 O GLU A 911  ? O GLU A 1033 
AB9 1 2 N ALA A 922  ? N ALA A 1044 O TYR A 931  ? O TYR A 1053 
AB9 2 3 N LEU A 930  ? N LEU A 1052 O HIS A 941  ? O HIS A 1063 
AB9 3 4 N LEU A 938  ? N LEU A 1060 O TYR A 951  ? O TYR A 1073 
AC1 1 2 N ALA A 962  ? N ALA A 1084 O LEU A 976  ? O LEU A 1098 
AC1 2 3 N VAL A 977  ? N VAL A 1099 O ARG A 984  ? O ARG A 1106 
AC1 3 4 N LEU A 985  ? N LEU A 1107 O ILE A 1000 ? O ILE A 1122 
AC2 1 2 N LEU A 1017 ? N LEU A 1139 O ALA A 1022 ? O ALA A 1144 
AC2 2 3 N LEU A 1023 ? N LEU A 1145 O VAL A 1036 ? O VAL A 1158 
AC2 3 4 N LEU A 1035 ? N LEU A 1157 O MET A 1045 ? O MET A 1167 
AC3 1 2 N ASP A 1087 ? N ASP A 1209 O HIS A 1095 ? O HIS A 1217 
AC3 2 3 N PHE A 1094 ? N PHE A 1216 O LEU A 1133 ? O LEU A 1255 
AC4 1 2 O LEU A 1126 ? O LEU A 1248 N TYR A 1111 ? N TYR A 1233 
AC4 2 3 N SER A 1110 ? N SER A 1232 O ARG A 1150 ? O ARG A 1272 
AC4 3 4 N ILE A 1147 ? N ILE A 1269 O THR A 1159 ? O THR A 1281 
# 
_pdbx_entry_details.entry_id                   9BFP 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_rmsd_angle.id 
_pdbx_validate_rmsd_angle.PDB_model_num 
_pdbx_validate_rmsd_angle.auth_atom_id_1 
_pdbx_validate_rmsd_angle.auth_asym_id_1 
_pdbx_validate_rmsd_angle.auth_comp_id_1 
_pdbx_validate_rmsd_angle.auth_seq_id_1 
_pdbx_validate_rmsd_angle.PDB_ins_code_1 
_pdbx_validate_rmsd_angle.label_alt_id_1 
_pdbx_validate_rmsd_angle.auth_atom_id_2 
_pdbx_validate_rmsd_angle.auth_asym_id_2 
_pdbx_validate_rmsd_angle.auth_comp_id_2 
_pdbx_validate_rmsd_angle.auth_seq_id_2 
_pdbx_validate_rmsd_angle.PDB_ins_code_2 
_pdbx_validate_rmsd_angle.label_alt_id_2 
_pdbx_validate_rmsd_angle.auth_atom_id_3 
_pdbx_validate_rmsd_angle.auth_asym_id_3 
_pdbx_validate_rmsd_angle.auth_comp_id_3 
_pdbx_validate_rmsd_angle.auth_seq_id_3 
_pdbx_validate_rmsd_angle.PDB_ins_code_3 
_pdbx_validate_rmsd_angle.label_alt_id_3 
_pdbx_validate_rmsd_angle.angle_value 
_pdbx_validate_rmsd_angle.angle_target_value 
_pdbx_validate_rmsd_angle.angle_deviation 
_pdbx_validate_rmsd_angle.angle_standard_deviation 
_pdbx_validate_rmsd_angle.linker_flag 
1 1 CA A LEU 232  ? ? CB A LEU 232  ? ? CG  A LEU 232  ? ? 133.22 115.30 17.92 2.30 N 
2 1 CB A ASP 807  ? ? CG A ASP 807  ? ? OD1 A ASP 807  ? ? 124.47 118.30 6.17  0.90 N 
3 1 CB A ASP 1089 ? ? CG A ASP 1089 ? ? OD2 A ASP 1089 ? ? 128.01 118.30 9.71  0.90 N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 ASP A 450 ? ? -148.48 -159.68 
2  1 ASN A 514 ? ? -116.57 -167.66 
3  1 ASN A 690 ? ? -110.38 -168.30 
4  1 GLN A 712 ? ? 54.34   73.92   
5  1 GLU A 788 ? ? -95.16  41.68   
6  1 GLN A 789 ? ? 69.55   -3.79   
7  1 LYS A 803 ? ? -120.69 -50.97  
8  1 THR A 941 ? ? -102.12 -167.21 
9  1 ASN A 942 ? ? -115.75 -161.22 
10 1 LEU A 958 ? ? 47.65   71.95   
11 1 CYS A 981 ? ? -161.41 117.54  
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BFP 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BFP 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.78 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               1173833 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'Sevenless extracellular domain' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BFP 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               OTHER 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             2000 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_sample_support.id               1 
_em_sample_support.film_material    ? 
_em_sample_support.method           ? 
_em_sample_support.grid_material    GOLD 
_em_sample_support.grid_mesh_size   ? 
_em_sample_support.grid_type        ? 
_em_sample_support.details          ? 
_em_sample_support.specimen_id      1 
_em_sample_support.citation_id      ? 
# 
_em_vitrification.entry_id              9BFP 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BFP 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A ASP 123  ? A ASP 1    
2   1 Y 1 A VAL 124  ? A VAL 2    
3   1 Y 1 A CYS 125  ? A CYS 3    
4   1 Y 1 A ARG 126  ? A ARG 4    
5   1 Y 1 A SER 127  ? A SER 5    
6   1 Y 1 A HIS 128  ? A HIS 6    
7   1 Y 1 A ASN 129  ? A ASN 7    
8   1 Y 1 A TYR 130  ? A TYR 8    
9   1 Y 1 A THR 131  ? A THR 9    
10  1 Y 1 A VAL 132  ? A VAL 10   
11  1 Y 1 A HIS 133  ? A HIS 11   
12  1 Y 1 A GLN 134  ? A GLN 12   
13  1 Y 1 A SER 135  ? A SER 13   
14  1 Y 1 A PRO 136  ? A PRO 14   
15  1 Y 1 A GLU 137  ? A GLU 15   
16  1 Y 1 A PRO 138  ? A PRO 16   
17  1 Y 1 A VAL 139  ? A VAL 17   
18  1 Y 1 A SER 140  ? A SER 18   
19  1 Y 1 A LYS 141  ? A LYS 19   
20  1 Y 1 A ASP 142  ? A ASP 20   
21  1 Y 1 A GLN 143  ? A GLN 21   
22  1 Y 1 A MET 144  ? A MET 22   
23  1 Y 1 A ARG 145  ? A ARG 23   
24  1 Y 1 A LEU 146  ? A LEU 24   
25  1 Y 1 A LEU 147  ? A LEU 25   
26  1 Y 1 A ARG 148  ? A ARG 26   
27  1 Y 1 A PRO 149  ? A PRO 27   
28  1 Y 1 A LYS 150  ? A LYS 28   
29  1 Y 1 A LEU 151  ? A LEU 29   
30  1 Y 1 A ASP 152  ? A ASP 30   
31  1 Y 1 A SER 153  ? A SER 31   
32  1 Y 1 A ASP 154  ? A ASP 32   
33  1 Y 1 A VAL 155  ? A VAL 33   
34  1 Y 1 A VAL 156  ? A VAL 34   
35  1 Y 1 A GLU 157  ? A GLU 35   
36  1 Y 1 A LYS 158  ? A LYS 36   
37  1 Y 1 A VAL 159  ? A VAL 37   
38  1 Y 1 A ALA 160  ? A ALA 38   
39  1 Y 1 A ILE 161  ? A ILE 39   
40  1 Y 1 A TRP 162  ? A TRP 40   
41  1 Y 1 A HIS 163  ? A HIS 41   
42  1 Y 1 A LYS 164  ? A LYS 42   
43  1 Y 1 A HIS 165  ? A HIS 43   
44  1 Y 1 A ALA 166  ? A ALA 44   
45  1 Y 1 A ALA 167  ? A ALA 45   
46  1 Y 1 A ALA 168  ? A ALA 46   
47  1 Y 1 A ALA 169  ? A ALA 47   
48  1 Y 1 A PRO 170  ? A PRO 48   
49  1 Y 1 A PRO 171  ? A PRO 49   
50  1 Y 1 A SER 172  ? A SER 50   
51  1 Y 1 A ILE 173  ? A ILE 51   
52  1 Y 1 A VAL 174  ? A VAL 52   
53  1 Y 1 A GLU 175  ? A GLU 53   
54  1 Y 1 A GLY 176  ? A GLY 54   
55  1 Y 1 A ILE 177  ? A ILE 55   
56  1 Y 1 A ALA 178  ? A ALA 56   
57  1 Y 1 A ILE 179  ? A ILE 57   
58  1 Y 1 A SER 180  ? A SER 58   
59  1 Y 1 A SER 181  ? A SER 59   
60  1 Y 1 A ARG 182  ? A ARG 60   
61  1 Y 1 A PRO 183  ? A PRO 61   
62  1 Y 1 A GLN 184  ? A GLN 62   
63  1 Y 1 A SER 185  ? A SER 63   
64  1 Y 1 A THR 186  ? A THR 64   
65  1 Y 1 A MET 187  ? A MET 65   
66  1 Y 1 A ALA 188  ? A ALA 66   
67  1 Y 1 A HIS 189  ? A HIS 67   
68  1 Y 1 A HIS 190  ? A HIS 68   
69  1 Y 1 A PRO 191  ? A PRO 69   
70  1 Y 1 A ASP 192  ? A ASP 70   
71  1 Y 1 A ASP 193  ? A ASP 71   
72  1 Y 1 A ARG 194  ? A ARG 72   
73  1 Y 1 A ASP 195  ? A ASP 73   
74  1 Y 1 A ARG 196  ? A ARG 74   
75  1 Y 1 A ASP 197  ? A ASP 75   
76  1 Y 1 A ARG 198  ? A ARG 76   
77  1 Y 1 A ASP 199  ? A ASP 77   
78  1 Y 1 A PRO 200  ? A PRO 78   
79  1 Y 1 A SER 201  ? A SER 79   
80  1 Y 1 A GLU 202  ? A GLU 80   
81  1 Y 1 A GLU 203  ? A GLU 81   
82  1 Y 1 A GLN 204  ? A GLN 82   
83  1 Y 1 A HIS 205  ? A HIS 83   
84  1 Y 1 A ALA 319  ? A ALA 197  
85  1 Y 1 A PRO 320  ? A PRO 198  
86  1 Y 1 A ARG 321  ? A ARG 199  
87  1 Y 1 A ALA 322  ? A ALA 200  
88  1 Y 1 A ASP 323  ? A ASP 201  
89  1 Y 1 A GLY 324  ? A GLY 202  
90  1 Y 1 A GLN 325  ? A GLN 203  
91  1 Y 1 A SER 326  ? A SER 204  
92  1 Y 1 A LEU 342  ? A LEU 220  
93  1 Y 1 A ALA 343  ? A ALA 221  
94  1 Y 1 A SER 344  ? A SER 222  
95  1 Y 1 A ARG 345  ? A ARG 223  
96  1 Y 1 A HIS 356  ? A HIS 234  
97  1 Y 1 A HIS 357  ? A HIS 235  
98  1 Y 1 A GLY 358  ? A GLY 236  
99  1 Y 1 A GLU 359  ? A GLU 237  
100 1 Y 1 A GLU 360  ? A GLU 238  
101 1 Y 1 A LEU 361  ? A LEU 239  
102 1 Y 1 A ASP 362  ? A ASP 240  
103 1 Y 1 A LEU 363  ? A LEU 241  
104 1 Y 1 A GLU 364  ? A GLU 242  
105 1 Y 1 A GLN 365  ? A GLN 243  
106 1 Y 1 A GLU 366  ? A GLU 244  
107 1 Y 1 A ASP 367  ? A ASP 245  
108 1 Y 1 A GLN 368  ? A GLN 246  
109 1 Y 1 A ASP 369  ? A ASP 247  
110 1 Y 1 A ALA 370  ? A ALA 248  
111 1 Y 1 A SER 371  ? A SER 249  
112 1 Y 1 A GLY 372  ? A GLY 250  
113 1 Y 1 A GLU 373  ? A GLU 251  
114 1 Y 1 A THR 374  ? A THR 252  
115 1 Y 1 A GLY 375  ? A GLY 253  
116 1 Y 1 A SER 376  ? A SER 254  
117 1 Y 1 A ARG 646  ? A ARG 524  
118 1 Y 1 A ASN 647  ? A ASN 525  
119 1 Y 1 A GLN 648  ? A GLN 526  
120 1 Y 1 A SER 649  ? A SER 527  
121 1 Y 1 A SER 754  ? A SER 632  
122 1 Y 1 A ASN 755  ? A ASN 633  
123 1 Y 1 A GLY 756  ? A GLY 634  
124 1 Y 1 A ALA 757  ? A ALA 635  
125 1 Y 1 A GLY 758  ? A GLY 636  
126 1 Y 1 A ASN 759  ? A ASN 637  
127 1 Y 1 A GLY 760  ? A GLY 638  
128 1 Y 1 A PRO 761  ? A PRO 639  
129 1 Y 1 A ALA 762  ? A ALA 640  
130 1 Y 1 A SER 763  ? A SER 641  
131 1 Y 1 A SER 764  ? A SER 642  
132 1 Y 1 A PRO 1288 ? A PRO 1166 
133 1 Y 1 A PRO 1289 ? A PRO 1167 
134 1 Y 1 A VAL 1290 ? A VAL 1168 
135 1 Y 1 A ALA 1291 ? A ALA 1169 
136 1 Y 1 A PRO 1292 ? A PRO 1170 
137 1 Y 1 A SER 1293 ? A SER 1171 
138 1 Y 1 A GLN 1294 ? A GLN 1172 
139 1 Y 1 A PRO 1295 ? A PRO 1173 
140 1 Y 1 A ARG 1296 ? A ARG 1174 
141 1 Y 1 A ARG 1297 ? A ARG 1175 
142 1 Y 1 A LEU 1298 ? A LEU 1176 
143 1 Y 1 A ARG 1299 ? A ARG 1177 
144 1 Y 1 A VAL 1300 ? A VAL 1178 
145 1 Y 1 A PHE 1301 ? A PHE 1179 
146 1 Y 1 A VAL 1302 ? A VAL 1180 
147 1 Y 1 A GLU 1303 ? A GLU 1181 
148 1 Y 1 A ARG 1304 ? A ARG 1182 
149 1 Y 1 A LEU 1305 ? A LEU 1183 
150 1 Y 1 A ALA 1306 ? A ALA 1184 
151 1 Y 1 A THR 1307 ? A THR 1185 
152 1 Y 1 A ALA 1308 ? A ALA 1186 
153 1 Y 1 A LEU 1309 ? A LEU 1187 
154 1 Y 1 A GLN 1310 ? A GLN 1188 
155 1 Y 1 A GLU 1311 ? A GLU 1189 
156 1 Y 1 A ALA 1312 ? A ALA 1190 
157 1 Y 1 A ASN 1313 ? A ASN 1191 
158 1 Y 1 A VAL 1314 ? A VAL 1192 
159 1 Y 1 A SER 1315 ? A SER 1193 
160 1 Y 1 A ALA 1316 ? A ALA 1194 
161 1 Y 1 A VAL 1317 ? A VAL 1195 
162 1 Y 1 A LEU 1318 ? A LEU 1196 
163 1 Y 1 A ARG 1319 ? A ARG 1197 
164 1 Y 1 A TRP 1320 ? A TRP 1198 
165 1 Y 1 A ASP 1321 ? A ASP 1199 
166 1 Y 1 A ALA 1322 ? A ALA 1200 
167 1 Y 1 A PRO 1323 ? A PRO 1201 
168 1 Y 1 A GLU 1324 ? A GLU 1202 
169 1 Y 1 A GLN 1325 ? A GLN 1203 
170 1 Y 1 A GLY 1326 ? A GLY 1204 
171 1 Y 1 A GLN 1327 ? A GLN 1205 
172 1 Y 1 A GLU 1328 ? A GLU 1206 
173 1 Y 1 A ALA 1329 ? A ALA 1207 
174 1 Y 1 A PRO 1330 ? A PRO 1208 
175 1 Y 1 A MET 1331 ? A MET 1209 
176 1 Y 1 A GLN 1332 ? A GLN 1210 
177 1 Y 1 A ALA 1333 ? A ALA 1211 
178 1 Y 1 A LEU 1334 ? A LEU 1212 
179 1 Y 1 A GLU 1335 ? A GLU 1213 
180 1 Y 1 A TYR 1336 ? A TYR 1214 
181 1 Y 1 A HIS 1337 ? A HIS 1215 
182 1 Y 1 A ILE 1338 ? A ILE 1216 
183 1 Y 1 A SER 1339 ? A SER 1217 
184 1 Y 1 A CYS 1340 ? A CYS 1218 
185 1 Y 1 A TRP 1341 ? A TRP 1219 
186 1 Y 1 A VAL 1342 ? A VAL 1220 
187 1 Y 1 A GLY 1343 ? A GLY 1221 
188 1 Y 1 A SER 1344 ? A SER 1222 
189 1 Y 1 A GLU 1345 ? A GLU 1223 
190 1 Y 1 A LEU 1346 ? A LEU 1224 
191 1 Y 1 A HIS 1347 ? A HIS 1225 
192 1 Y 1 A GLU 1348 ? A GLU 1226 
193 1 Y 1 A GLU 1349 ? A GLU 1227 
194 1 Y 1 A LEU 1350 ? A LEU 1228 
195 1 Y 1 A ARG 1351 ? A ARG 1229 
196 1 Y 1 A LEU 1352 ? A LEU 1230 
197 1 Y 1 A ASN 1353 ? A ASN 1231 
198 1 Y 1 A GLN 1354 ? A GLN 1232 
199 1 Y 1 A SER 1355 ? A SER 1233 
200 1 Y 1 A ALA 1356 ? A ALA 1234 
201 1 Y 1 A LEU 1357 ? A LEU 1235 
202 1 Y 1 A GLU 1358 ? A GLU 1236 
203 1 Y 1 A ALA 1359 ? A ALA 1237 
204 1 Y 1 A ARG 1360 ? A ARG 1238 
205 1 Y 1 A VAL 1361 ? A VAL 1239 
206 1 Y 1 A GLU 1362 ? A GLU 1240 
207 1 Y 1 A HIS 1363 ? A HIS 1241 
208 1 Y 1 A LEU 1364 ? A LEU 1242 
209 1 Y 1 A GLN 1365 ? A GLN 1243 
210 1 Y 1 A PRO 1366 ? A PRO 1244 
211 1 Y 1 A ASP 1367 ? A ASP 1245 
212 1 Y 1 A GLN 1368 ? A GLN 1246 
213 1 Y 1 A THR 1369 ? A THR 1247 
214 1 Y 1 A TYR 1370 ? A TYR 1248 
215 1 Y 1 A HIS 1371 ? A HIS 1249 
216 1 Y 1 A PHE 1372 ? A PHE 1250 
217 1 Y 1 A GLN 1373 ? A GLN 1251 
218 1 Y 1 A VAL 1374 ? A VAL 1252 
219 1 Y 1 A GLU 1375 ? A GLU 1253 
220 1 Y 1 A ALA 1376 ? A ALA 1254 
221 1 Y 1 A ARG 1377 ? A ARG 1255 
222 1 Y 1 A VAL 1378 ? A VAL 1256 
223 1 Y 1 A ALA 1379 ? A ALA 1257 
224 1 Y 1 A ALA 1380 ? A ALA 1258 
225 1 Y 1 A THR 1381 ? A THR 1259 
226 1 Y 1 A GLY 1382 ? A GLY 1260 
227 1 Y 1 A ALA 1383 ? A ALA 1261 
228 1 Y 1 A ALA 1384 ? A ALA 1262 
229 1 Y 1 A ALA 1385 ? A ALA 1263 
230 1 Y 1 A GLY 1386 ? A GLY 1264 
231 1 Y 1 A ALA 1387 ? A ALA 1265 
232 1 Y 1 A ALA 1388 ? A ALA 1266 
233 1 Y 1 A SER 1389 ? A SER 1267 
234 1 Y 1 A HIS 1390 ? A HIS 1268 
235 1 Y 1 A ALA 1391 ? A ALA 1269 
236 1 Y 1 A LEU 1392 ? A LEU 1270 
237 1 Y 1 A HIS 1393 ? A HIS 1271 
238 1 Y 1 A VAL 1394 ? A VAL 1272 
239 1 Y 1 A ALA 1395 ? A ALA 1273 
240 1 Y 1 A PRO 1396 ? A PRO 1274 
241 1 Y 1 A GLU 1397 ? A GLU 1275 
242 1 Y 1 A VAL 1398 ? A VAL 1276 
243 1 Y 1 A GLN 1399 ? A GLN 1277 
244 1 Y 1 A ALA 1400 ? A ALA 1278 
245 1 Y 1 A VAL 1401 ? A VAL 1279 
246 1 Y 1 A PRO 1402 ? A PRO 1280 
247 1 Y 1 A ARG 1403 ? A ARG 1281 
248 1 Y 1 A VAL 1404 ? A VAL 1282 
249 1 Y 1 A LEU 1405 ? A LEU 1283 
250 1 Y 1 A TYR 1406 ? A TYR 1284 
251 1 Y 1 A ALA 1407 ? A ALA 1285 
252 1 Y 1 A ASN 1408 ? A ASN 1286 
253 1 Y 1 A ALA 1409 ? A ALA 1287 
254 1 Y 1 A GLU 1410 ? A GLU 1288 
255 1 Y 1 A PHE 1411 ? A PHE 1289 
256 1 Y 1 A ILE 1412 ? A ILE 1290 
257 1 Y 1 A GLY 1413 ? A GLY 1291 
258 1 Y 1 A GLU 1414 ? A GLU 1292 
259 1 Y 1 A LEU 1415 ? A LEU 1293 
260 1 Y 1 A ASP 1416 ? A ASP 1294 
261 1 Y 1 A LEU 1417 ? A LEU 1295 
262 1 Y 1 A ASP 1418 ? A ASP 1296 
263 1 Y 1 A THR 1419 ? A THR 1297 
264 1 Y 1 A ARG 1420 ? A ARG 1298 
265 1 Y 1 A ASN 1421 ? A ASN 1299 
266 1 Y 1 A ARG 1422 ? A ARG 1300 
267 1 Y 1 A ARG 1423 ? A ARG 1301 
268 1 Y 1 A ARG 1424 ? A ARG 1302 
269 1 Y 1 A LEU 1425 ? A LEU 1303 
270 1 Y 1 A VAL 1426 ? A VAL 1304 
271 1 Y 1 A HIS 1427 ? A HIS 1305 
272 1 Y 1 A THR 1428 ? A THR 1306 
273 1 Y 1 A ALA 1429 ? A ALA 1307 
274 1 Y 1 A SER 1430 ? A SER 1308 
275 1 Y 1 A PRO 1431 ? A PRO 1309 
276 1 Y 1 A VAL 1432 ? A VAL 1310 
277 1 Y 1 A GLU 1433 ? A GLU 1311 
278 1 Y 1 A HIS 1434 ? A HIS 1312 
279 1 Y 1 A LEU 1435 ? A LEU 1313 
280 1 Y 1 A VAL 1436 ? A VAL 1314 
281 1 Y 1 A GLY 1437 ? A GLY 1315 
282 1 Y 1 A ILE 1438 ? A ILE 1316 
283 1 Y 1 A GLU 1439 ? A GLU 1317 
284 1 Y 1 A GLY 1440 ? A GLY 1318 
285 1 Y 1 A GLU 1441 ? A GLU 1319 
286 1 Y 1 A GLN 1442 ? A GLN 1320 
287 1 Y 1 A ARG 1443 ? A ARG 1321 
288 1 Y 1 A LEU 1444 ? A LEU 1322 
289 1 Y 1 A LEU 1445 ? A LEU 1323 
290 1 Y 1 A TRP 1446 ? A TRP 1324 
291 1 Y 1 A VAL 1447 ? A VAL 1325 
292 1 Y 1 A ASN 1448 ? A ASN 1326 
293 1 Y 1 A GLU 1449 ? A GLU 1327 
294 1 Y 1 A HIS 1450 ? A HIS 1328 
295 1 Y 1 A VAL 1451 ? A VAL 1329 
296 1 Y 1 A GLU 1452 ? A GLU 1330 
297 1 Y 1 A LEU 1453 ? A LEU 1331 
298 1 Y 1 A LEU 1454 ? A LEU 1332 
299 1 Y 1 A THR 1455 ? A THR 1333 
300 1 Y 1 A HIS 1456 ? A HIS 1334 
301 1 Y 1 A VAL 1457 ? A VAL 1335 
302 1 Y 1 A PRO 1458 ? A PRO 1336 
303 1 Y 1 A GLY 1459 ? A GLY 1337 
304 1 Y 1 A SER 1460 ? A SER 1338 
305 1 Y 1 A ALA 1461 ? A ALA 1339 
306 1 Y 1 A PRO 1462 ? A PRO 1340 
307 1 Y 1 A ALA 1463 ? A ALA 1341 
308 1 Y 1 A LYS 1464 ? A LYS 1342 
309 1 Y 1 A LEU 1465 ? A LEU 1343 
310 1 Y 1 A ALA 1466 ? A ALA 1344 
311 1 Y 1 A ARG 1467 ? A ARG 1345 
312 1 Y 1 A MET 1468 ? A MET 1346 
313 1 Y 1 A ARG 1469 ? A ARG 1347 
314 1 Y 1 A ALA 1470 ? A ALA 1348 
315 1 Y 1 A GLU 1471 ? A GLU 1349 
316 1 Y 1 A VAL 1472 ? A VAL 1350 
317 1 Y 1 A LEU 1473 ? A LEU 1351 
318 1 Y 1 A ALA 1474 ? A ALA 1352 
319 1 Y 1 A LEU 1475 ? A LEU 1353 
320 1 Y 1 A ALA 1476 ? A ALA 1354 
321 1 Y 1 A VAL 1477 ? A VAL 1355 
322 1 Y 1 A ASP 1478 ? A ASP 1356 
323 1 Y 1 A TRP 1479 ? A TRP 1357 
324 1 Y 1 A ILE 1480 ? A ILE 1358 
325 1 Y 1 A GLN 1481 ? A GLN 1359 
326 1 Y 1 A ARG 1482 ? A ARG 1360 
327 1 Y 1 A ILE 1483 ? A ILE 1361 
328 1 Y 1 A VAL 1484 ? A VAL 1362 
329 1 Y 1 A TYR 1485 ? A TYR 1363 
330 1 Y 1 A TRP 1486 ? A TRP 1364 
331 1 Y 1 A ALA 1487 ? A ALA 1365 
332 1 Y 1 A GLU 1488 ? A GLU 1366 
333 1 Y 1 A LEU 1489 ? A LEU 1367 
334 1 Y 1 A ASP 1490 ? A ASP 1368 
335 1 Y 1 A ALA 1491 ? A ALA 1369 
336 1 Y 1 A THR 1492 ? A THR 1370 
337 1 Y 1 A ALA 1493 ? A ALA 1371 
338 1 Y 1 A PRO 1494 ? A PRO 1372 
339 1 Y 1 A GLN 1495 ? A GLN 1373 
340 1 Y 1 A ALA 1496 ? A ALA 1374 
341 1 Y 1 A ALA 1497 ? A ALA 1375 
342 1 Y 1 A ILE 1498 ? A ILE 1376 
343 1 Y 1 A ILE 1499 ? A ILE 1377 
344 1 Y 1 A TYR 1500 ? A TYR 1378 
345 1 Y 1 A ARG 1501 ? A ARG 1379 
346 1 Y 1 A LEU 1502 ? A LEU 1380 
347 1 Y 1 A ASP 1503 ? A ASP 1381 
348 1 Y 1 A LEU 1504 ? A LEU 1382 
349 1 Y 1 A CYS 1505 ? A CYS 1383 
350 1 Y 1 A ASN 1506 ? A ASN 1384 
351 1 Y 1 A PHE 1507 ? A PHE 1385 
352 1 Y 1 A GLU 1508 ? A GLU 1386 
353 1 Y 1 A GLY 1509 ? A GLY 1387 
354 1 Y 1 A LYS 1510 ? A LYS 1388 
355 1 Y 1 A ILE 1511 ? A ILE 1389 
356 1 Y 1 A LEU 1512 ? A LEU 1390 
357 1 Y 1 A GLN 1513 ? A GLN 1391 
358 1 Y 1 A GLY 1514 ? A GLY 1392 
359 1 Y 1 A GLU 1515 ? A GLU 1393 
360 1 Y 1 A ARG 1516 ? A ARG 1394 
361 1 Y 1 A VAL 1517 ? A VAL 1395 
362 1 Y 1 A TRP 1518 ? A TRP 1396 
363 1 Y 1 A SER 1519 ? A SER 1397 
364 1 Y 1 A THR 1520 ? A THR 1398 
365 1 Y 1 A PRO 1521 ? A PRO 1399 
366 1 Y 1 A ARG 1522 ? A ARG 1400 
367 1 Y 1 A GLY 1523 ? A GLY 1401 
368 1 Y 1 A ARG 1524 ? A ARG 1402 
369 1 Y 1 A LEU 1525 ? A LEU 1403 
370 1 Y 1 A LEU 1526 ? A LEU 1404 
371 1 Y 1 A LYS 1527 ? A LYS 1405 
372 1 Y 1 A ASP 1528 ? A ASP 1406 
373 1 Y 1 A LEU 1529 ? A LEU 1407 
374 1 Y 1 A VAL 1530 ? A VAL 1408 
375 1 Y 1 A ALA 1531 ? A ALA 1409 
376 1 Y 1 A LEU 1532 ? A LEU 1410 
377 1 Y 1 A PRO 1533 ? A PRO 1411 
378 1 Y 1 A GLN 1534 ? A GLN 1412 
379 1 Y 1 A ALA 1535 ? A ALA 1413 
380 1 Y 1 A GLN 1536 ? A GLN 1414 
381 1 Y 1 A SER 1537 ? A SER 1415 
382 1 Y 1 A LEU 1538 ? A LEU 1416 
383 1 Y 1 A ILE 1539 ? A ILE 1417 
384 1 Y 1 A TRP 1540 ? A TRP 1418 
385 1 Y 1 A LEU 1541 ? A LEU 1419 
386 1 Y 1 A GLU 1542 ? A GLU 1420 
387 1 Y 1 A TYR 1543 ? A TYR 1421 
388 1 Y 1 A GLU 1544 ? A GLU 1422 
389 1 Y 1 A GLN 1545 ? A GLN 1423 
390 1 Y 1 A GLY 1546 ? A GLY 1424 
391 1 Y 1 A SER 1547 ? A SER 1425 
392 1 Y 1 A PRO 1548 ? A PRO 1426 
393 1 Y 1 A ARG 1549 ? A ARG 1427 
394 1 Y 1 A ASN 1550 ? A ASN 1428 
395 1 Y 1 A GLY 1551 ? A GLY 1429 
396 1 Y 1 A SER 1552 ? A SER 1430 
397 1 Y 1 A LEU 1553 ? A LEU 1431 
398 1 Y 1 A ARG 1554 ? A ARG 1432 
399 1 Y 1 A GLY 1555 ? A GLY 1433 
400 1 Y 1 A ARG 1556 ? A ARG 1434 
401 1 Y 1 A ASN 1557 ? A ASN 1435 
402 1 Y 1 A LEU 1558 ? A LEU 1436 
403 1 Y 1 A THR 1559 ? A THR 1437 
404 1 Y 1 A ASP 1560 ? A ASP 1438 
405 1 Y 1 A GLY 1561 ? A GLY 1439 
406 1 Y 1 A SER 1562 ? A SER 1440 
407 1 Y 1 A GLU 1563 ? A GLU 1441 
408 1 Y 1 A LEU 1564 ? A LEU 1442 
409 1 Y 1 A GLU 1565 ? A GLU 1443 
410 1 Y 1 A TRP 1566 ? A TRP 1444 
411 1 Y 1 A ALA 1567 ? A ALA 1445 
412 1 Y 1 A THR 1568 ? A THR 1446 
413 1 Y 1 A VAL 1569 ? A VAL 1447 
414 1 Y 1 A GLN 1570 ? A GLN 1448 
415 1 Y 1 A PRO 1571 ? A PRO 1449 
416 1 Y 1 A LEU 1572 ? A LEU 1450 
417 1 Y 1 A ILE 1573 ? A ILE 1451 
418 1 Y 1 A ARG 1574 ? A ARG 1452 
419 1 Y 1 A LEU 1575 ? A LEU 1453 
420 1 Y 1 A HIS 1576 ? A HIS 1454 
421 1 Y 1 A ALA 1577 ? A ALA 1455 
422 1 Y 1 A GLY 1578 ? A GLY 1456 
423 1 Y 1 A SER 1579 ? A SER 1457 
424 1 Y 1 A LEU 1580 ? A LEU 1458 
425 1 Y 1 A GLU 1581 ? A GLU 1459 
426 1 Y 1 A PRO 1582 ? A PRO 1460 
427 1 Y 1 A GLY 1583 ? A GLY 1461 
428 1 Y 1 A SER 1584 ? A SER 1462 
429 1 Y 1 A GLU 1585 ? A GLU 1463 
430 1 Y 1 A THR 1586 ? A THR 1464 
431 1 Y 1 A LEU 1587 ? A LEU 1465 
432 1 Y 1 A ASN 1588 ? A ASN 1466 
433 1 Y 1 A LEU 1589 ? A LEU 1467 
434 1 Y 1 A VAL 1590 ? A VAL 1468 
435 1 Y 1 A ASP 1591 ? A ASP 1469 
436 1 Y 1 A ASN 1592 ? A ASN 1470 
437 1 Y 1 A GLN 1593 ? A GLN 1471 
438 1 Y 1 A GLY 1594 ? A GLY 1472 
439 1 Y 1 A LYS 1595 ? A LYS 1473 
440 1 Y 1 A LEU 1596 ? A LEU 1474 
441 1 Y 1 A CYS 1597 ? A CYS 1475 
442 1 Y 1 A VAL 1598 ? A VAL 1476 
443 1 Y 1 A TYR 1599 ? A TYR 1477 
444 1 Y 1 A ASP 1600 ? A ASP 1478 
445 1 Y 1 A VAL 1601 ? A VAL 1479 
446 1 Y 1 A ALA 1602 ? A ALA 1480 
447 1 Y 1 A ARG 1603 ? A ARG 1481 
448 1 Y 1 A GLN 1604 ? A GLN 1482 
449 1 Y 1 A LEU 1605 ? A LEU 1483 
450 1 Y 1 A CYS 1606 ? A CYS 1484 
451 1 Y 1 A THR 1607 ? A THR 1485 
452 1 Y 1 A ALA 1608 ? A ALA 1486 
453 1 Y 1 A SER 1609 ? A SER 1487 
454 1 Y 1 A ALA 1610 ? A ALA 1488 
455 1 Y 1 A LEU 1611 ? A LEU 1489 
456 1 Y 1 A ARG 1612 ? A ARG 1490 
457 1 Y 1 A ALA 1613 ? A ALA 1491 
458 1 Y 1 A GLN 1614 ? A GLN 1492 
459 1 Y 1 A LEU 1615 ? A LEU 1493 
460 1 Y 1 A ASN 1616 ? A ASN 1494 
461 1 Y 1 A LEU 1617 ? A LEU 1495 
462 1 Y 1 A LEU 1618 ? A LEU 1496 
463 1 Y 1 A GLY 1619 ? A GLY 1497 
464 1 Y 1 A GLU 1620 ? A GLU 1498 
465 1 Y 1 A ASP 1621 ? A ASP 1499 
466 1 Y 1 A SER 1622 ? A SER 1500 
467 1 Y 1 A ILE 1623 ? A ILE 1501 
468 1 Y 1 A ALA 1624 ? A ALA 1502 
469 1 Y 1 A GLY 1625 ? A GLY 1503 
470 1 Y 1 A GLN 1626 ? A GLN 1504 
471 1 Y 1 A LEU 1627 ? A LEU 1505 
472 1 Y 1 A ALA 1628 ? A ALA 1506 
473 1 Y 1 A GLN 1629 ? A GLN 1507 
474 1 Y 1 A ASP 1630 ? A ASP 1508 
475 1 Y 1 A SER 1631 ? A SER 1509 
476 1 Y 1 A GLY 1632 ? A GLY 1510 
477 1 Y 1 A TYR 1633 ? A TYR 1511 
478 1 Y 1 A LEU 1634 ? A LEU 1512 
479 1 Y 1 A TYR 1635 ? A TYR 1513 
480 1 Y 1 A ALA 1636 ? A ALA 1514 
481 1 Y 1 A VAL 1637 ? A VAL 1515 
482 1 Y 1 A LYS 1638 ? A LYS 1516 
483 1 Y 1 A ASN 1639 ? A ASN 1517 
484 1 Y 1 A TRP 1640 ? A TRP 1518 
485 1 Y 1 A SER 1641 ? A SER 1519 
486 1 Y 1 A ILE 1642 ? A ILE 1520 
487 1 Y 1 A ARG 1643 ? A ARG 1521 
488 1 Y 1 A ALA 1644 ? A ALA 1522 
489 1 Y 1 A TYR 1645 ? A TYR 1523 
490 1 Y 1 A GLY 1646 ? A GLY 1524 
491 1 Y 1 A ARG 1647 ? A ARG 1525 
492 1 Y 1 A ARG 1648 ? A ARG 1526 
493 1 Y 1 A ARG 1649 ? A ARG 1527 
494 1 Y 1 A GLN 1650 ? A GLN 1528 
495 1 Y 1 A GLN 1651 ? A GLN 1529 
496 1 Y 1 A LEU 1652 ? A LEU 1530 
497 1 Y 1 A GLU 1653 ? A GLU 1531 
498 1 Y 1 A TYR 1654 ? A TYR 1532 
499 1 Y 1 A THR 1655 ? A THR 1533 
500 1 Y 1 A VAL 1656 ? A VAL 1534 
501 1 Y 1 A GLU 1657 ? A GLU 1535 
502 1 Y 1 A LEU 1658 ? A LEU 1536 
503 1 Y 1 A GLU 1659 ? A GLU 1537 
504 1 Y 1 A PRO 1660 ? A PRO 1538 
505 1 Y 1 A GLU 1661 ? A GLU 1539 
506 1 Y 1 A GLU 1662 ? A GLU 1540 
507 1 Y 1 A VAL 1663 ? A VAL 1541 
508 1 Y 1 A ARG 1664 ? A ARG 1542 
509 1 Y 1 A LEU 1665 ? A LEU 1543 
510 1 Y 1 A LEU 1666 ? A LEU 1544 
511 1 Y 1 A GLN 1667 ? A GLN 1545 
512 1 Y 1 A ALA 1668 ? A ALA 1546 
513 1 Y 1 A HIS 1669 ? A HIS 1547 
514 1 Y 1 A ASN 1670 ? A ASN 1548 
515 1 Y 1 A TYR 1671 ? A TYR 1549 
516 1 Y 1 A GLN 1672 ? A GLN 1550 
517 1 Y 1 A ALA 1673 ? A ALA 1551 
518 1 Y 1 A TYR 1674 ? A TYR 1552 
519 1 Y 1 A PRO 1675 ? A PRO 1553 
520 1 Y 1 A PRO 1676 ? A PRO 1554 
521 1 Y 1 A LYS 1677 ? A LYS 1555 
522 1 Y 1 A ASN 1678 ? A ASN 1556 
523 1 Y 1 A CYS 1679 ? A CYS 1557 
524 1 Y 1 A LEU 1680 ? A LEU 1558 
525 1 Y 1 A LEU 1681 ? A LEU 1559 
526 1 Y 1 A LEU 1682 ? A LEU 1560 
527 1 Y 1 A PRO 1683 ? A PRO 1561 
528 1 Y 1 A SER 1684 ? A SER 1562 
529 1 Y 1 A SER 1685 ? A SER 1563 
530 1 Y 1 A GLY 1686 ? A GLY 1564 
531 1 Y 1 A GLY 1687 ? A GLY 1565 
532 1 Y 1 A SER 1688 ? A SER 1566 
533 1 Y 1 A LEU 1689 ? A LEU 1567 
534 1 Y 1 A LEU 1690 ? A LEU 1568 
535 1 Y 1 A LYS 1691 ? A LYS 1569 
536 1 Y 1 A ALA 1692 ? A ALA 1570 
537 1 Y 1 A THR 1693 ? A THR 1571 
538 1 Y 1 A ASP 1694 ? A ASP 1572 
539 1 Y 1 A CYS 1695 ? A CYS 1573 
540 1 Y 1 A GLU 1696 ? A GLU 1574 
541 1 Y 1 A GLU 1697 ? A GLU 1575 
542 1 Y 1 A GLN 1698 ? A GLN 1576 
543 1 Y 1 A ARG 1699 ? A ARG 1577 
544 1 Y 1 A CYS 1700 ? A CYS 1578 
545 1 Y 1 A LEU 1701 ? A LEU 1579 
546 1 Y 1 A LEU 1702 ? A LEU 1580 
547 1 Y 1 A ASN 1703 ? A ASN 1581 
548 1 Y 1 A LEU 1704 ? A LEU 1582 
549 1 Y 1 A PRO 1705 ? A PRO 1583 
550 1 Y 1 A MET 1706 ? A MET 1584 
551 1 Y 1 A ILE 1707 ? A ILE 1585 
552 1 Y 1 A THR 1708 ? A THR 1586 
553 1 Y 1 A ALA 1709 ? A ALA 1587 
554 1 Y 1 A SER 1710 ? A SER 1588 
555 1 Y 1 A GLU 1711 ? A GLU 1589 
556 1 Y 1 A ASP 1712 ? A ASP 1590 
557 1 Y 1 A CYS 1713 ? A CYS 1591 
558 1 Y 1 A PRO 1714 ? A PRO 1592 
559 1 Y 1 A LEU 1715 ? A LEU 1593 
560 1 Y 1 A PRO 1716 ? A PRO 1594 
561 1 Y 1 A ILE 1717 ? A ILE 1595 
562 1 Y 1 A PRO 1718 ? A PRO 1596 
563 1 Y 1 A GLY 1719 ? A GLY 1597 
564 1 Y 1 A VAL 1720 ? A VAL 1598 
565 1 Y 1 A ARG 1721 ? A ARG 1599 
566 1 Y 1 A TYR 1722 ? A TYR 1600 
567 1 Y 1 A GLN 1723 ? A GLN 1601 
568 1 Y 1 A LEU 1724 ? A LEU 1602 
569 1 Y 1 A ASN 1725 ? A ASN 1603 
570 1 Y 1 A LEU 1726 ? A LEU 1604 
571 1 Y 1 A THR 1727 ? A THR 1605 
572 1 Y 1 A LEU 1728 ? A LEU 1606 
573 1 Y 1 A ALA 1729 ? A ALA 1607 
574 1 Y 1 A ARG 1730 ? A ARG 1608 
575 1 Y 1 A GLY 1731 ? A GLY 1609 
576 1 Y 1 A PRO 1732 ? A PRO 1610 
577 1 Y 1 A GLY 1733 ? A GLY 1611 
578 1 Y 1 A SER 1734 ? A SER 1612 
579 1 Y 1 A GLU 1735 ? A GLU 1613 
580 1 Y 1 A GLU 1736 ? A GLU 1614 
581 1 Y 1 A HIS 1737 ? A HIS 1615 
582 1 Y 1 A ASP 1738 ? A ASP 1616 
583 1 Y 1 A HIS 1739 ? A HIS 1617 
584 1 Y 1 A GLY 1740 ? A GLY 1618 
585 1 Y 1 A VAL 1741 ? A VAL 1619 
586 1 Y 1 A GLU 1742 ? A GLU 1620 
587 1 Y 1 A PRO 1743 ? A PRO 1621 
588 1 Y 1 A LEU 1744 ? A LEU 1622 
589 1 Y 1 A GLY 1745 ? A GLY 1623 
590 1 Y 1 A GLN 1746 ? A GLN 1624 
591 1 Y 1 A TRP 1747 ? A TRP 1625 
592 1 Y 1 A LEU 1748 ? A LEU 1626 
593 1 Y 1 A LEU 1749 ? A LEU 1627 
594 1 Y 1 A GLY 1750 ? A GLY 1628 
595 1 Y 1 A ALA 1751 ? A ALA 1629 
596 1 Y 1 A GLY 1752 ? A GLY 1630 
597 1 Y 1 A GLU 1753 ? A GLU 1631 
598 1 Y 1 A SER 1754 ? A SER 1632 
599 1 Y 1 A LEU 1755 ? A LEU 1633 
600 1 Y 1 A ASN 1756 ? A ASN 1634 
601 1 Y 1 A LEU 1757 ? A LEU 1635 
602 1 Y 1 A THR 1758 ? A THR 1636 
603 1 Y 1 A ASP 1759 ? A ASP 1637 
604 1 Y 1 A LEU 1760 ? A LEU 1638 
605 1 Y 1 A LEU 1761 ? A LEU 1639 
606 1 Y 1 A PRO 1762 ? A PRO 1640 
607 1 Y 1 A PHE 1763 ? A PHE 1641 
608 1 Y 1 A THR 1764 ? A THR 1642 
609 1 Y 1 A ARG 1765 ? A ARG 1643 
610 1 Y 1 A TYR 1766 ? A TYR 1644 
611 1 Y 1 A ARG 1767 ? A ARG 1645 
612 1 Y 1 A VAL 1768 ? A VAL 1646 
613 1 Y 1 A SER 1769 ? A SER 1647 
614 1 Y 1 A GLY 1770 ? A GLY 1648 
615 1 Y 1 A ILE 1771 ? A ILE 1649 
616 1 Y 1 A LEU 1772 ? A LEU 1650 
617 1 Y 1 A SER 1773 ? A SER 1651 
618 1 Y 1 A SER 1774 ? A SER 1652 
619 1 Y 1 A PHE 1775 ? A PHE 1653 
620 1 Y 1 A TYR 1776 ? A TYR 1654 
621 1 Y 1 A GLN 1777 ? A GLN 1655 
622 1 Y 1 A LYS 1778 ? A LYS 1656 
623 1 Y 1 A LYS 1779 ? A LYS 1657 
624 1 Y 1 A LEU 1780 ? A LEU 1658 
625 1 Y 1 A ALA 1781 ? A ALA 1659 
626 1 Y 1 A LEU 1782 ? A LEU 1660 
627 1 Y 1 A PRO 1783 ? A PRO 1661 
628 1 Y 1 A THR 1784 ? A THR 1662 
629 1 Y 1 A LEU 1785 ? A LEU 1663 
630 1 Y 1 A VAL 1786 ? A VAL 1664 
631 1 Y 1 A LEU 1787 ? A LEU 1665 
632 1 Y 1 A ALA 1788 ? A ALA 1666 
633 1 Y 1 A PRO 1789 ? A PRO 1667 
634 1 Y 1 A LEU 1790 ? A LEU 1668 
635 1 Y 1 A GLU 1791 ? A GLU 1669 
636 1 Y 1 A LEU 1792 ? A LEU 1670 
637 1 Y 1 A LEU 1793 ? A LEU 1671 
638 1 Y 1 A THR 1794 ? A THR 1672 
639 1 Y 1 A ALA 1795 ? A ALA 1673 
640 1 Y 1 A SER 1796 ? A SER 1674 
641 1 Y 1 A ALA 1797 ? A ALA 1675 
642 1 Y 1 A THR 1798 ? A THR 1676 
643 1 Y 1 A PRO 1799 ? A PRO 1677 
644 1 Y 1 A SER 1800 ? A SER 1678 
645 1 Y 1 A PRO 1801 ? A PRO 1679 
646 1 Y 1 A PRO 1802 ? A PRO 1680 
647 1 Y 1 A ARG 1803 ? A ARG 1681 
648 1 Y 1 A ASN 1804 ? A ASN 1682 
649 1 Y 1 A PHE 1805 ? A PHE 1683 
650 1 Y 1 A SER 1806 ? A SER 1684 
651 1 Y 1 A VAL 1807 ? A VAL 1685 
652 1 Y 1 A ARG 1808 ? A ARG 1686 
653 1 Y 1 A VAL 1809 ? A VAL 1687 
654 1 Y 1 A LEU 1810 ? A LEU 1688 
655 1 Y 1 A SER 1811 ? A SER 1689 
656 1 Y 1 A PRO 1812 ? A PRO 1690 
657 1 Y 1 A ARG 1813 ? A ARG 1691 
658 1 Y 1 A GLU 1814 ? A GLU 1692 
659 1 Y 1 A LEU 1815 ? A LEU 1693 
660 1 Y 1 A GLU 1816 ? A GLU 1694 
661 1 Y 1 A VAL 1817 ? A VAL 1695 
662 1 Y 1 A SER 1818 ? A SER 1696 
663 1 Y 1 A TRP 1819 ? A TRP 1697 
664 1 Y 1 A LEU 1820 ? A LEU 1698 
665 1 Y 1 A PRO 1821 ? A PRO 1699 
666 1 Y 1 A PRO 1822 ? A PRO 1700 
667 1 Y 1 A GLU 1823 ? A GLU 1701 
668 1 Y 1 A GLN 1824 ? A GLN 1702 
669 1 Y 1 A LEU 1825 ? A LEU 1703 
670 1 Y 1 A ARG 1826 ? A ARG 1704 
671 1 Y 1 A SER 1827 ? A SER 1705 
672 1 Y 1 A GLU 1828 ? A GLU 1706 
673 1 Y 1 A SER 1829 ? A SER 1707 
674 1 Y 1 A VAL 1830 ? A VAL 1708 
675 1 Y 1 A TYR 1831 ? A TYR 1709 
676 1 Y 1 A TYR 1832 ? A TYR 1710 
677 1 Y 1 A THR 1833 ? A THR 1711 
678 1 Y 1 A LEU 1834 ? A LEU 1712 
679 1 Y 1 A HIS 1835 ? A HIS 1713 
680 1 Y 1 A TRP 1836 ? A TRP 1714 
681 1 Y 1 A GLN 1837 ? A GLN 1715 
682 1 Y 1 A GLN 1838 ? A GLN 1716 
683 1 Y 1 A GLU 1839 ? A GLU 1717 
684 1 Y 1 A LEU 1840 ? A LEU 1718 
685 1 Y 1 A ASP 1841 ? A ASP 1719 
686 1 Y 1 A GLY 1842 ? A GLY 1720 
687 1 Y 1 A GLU 1843 ? A GLU 1721 
688 1 Y 1 A ASN 1844 ? A ASN 1722 
689 1 Y 1 A VAL 1845 ? A VAL 1723 
690 1 Y 1 A GLN 1846 ? A GLN 1724 
691 1 Y 1 A ASP 1847 ? A ASP 1725 
692 1 Y 1 A ARG 1848 ? A ARG 1726 
693 1 Y 1 A ARG 1849 ? A ARG 1727 
694 1 Y 1 A GLU 1850 ? A GLU 1728 
695 1 Y 1 A TRP 1851 ? A TRP 1729 
696 1 Y 1 A GLU 1852 ? A GLU 1730 
697 1 Y 1 A ALA 1853 ? A ALA 1731 
698 1 Y 1 A HIS 1854 ? A HIS 1732 
699 1 Y 1 A GLU 1855 ? A GLU 1733 
700 1 Y 1 A ARG 1856 ? A ARG 1734 
701 1 Y 1 A ARG 1857 ? A ARG 1735 
702 1 Y 1 A LEU 1858 ? A LEU 1736 
703 1 Y 1 A GLU 1859 ? A GLU 1737 
704 1 Y 1 A THR 1860 ? A THR 1738 
705 1 Y 1 A ALA 1861 ? A ALA 1739 
706 1 Y 1 A GLY 1862 ? A GLY 1740 
707 1 Y 1 A THR 1863 ? A THR 1741 
708 1 Y 1 A HIS 1864 ? A HIS 1742 
709 1 Y 1 A ARG 1865 ? A ARG 1743 
710 1 Y 1 A LEU 1866 ? A LEU 1744 
711 1 Y 1 A THR 1867 ? A THR 1745 
712 1 Y 1 A GLY 1868 ? A GLY 1746 
713 1 Y 1 A ILE 1869 ? A ILE 1747 
714 1 Y 1 A LYS 1870 ? A LYS 1748 
715 1 Y 1 A PRO 1871 ? A PRO 1749 
716 1 Y 1 A GLY 1872 ? A GLY 1750 
717 1 Y 1 A SER 1873 ? A SER 1751 
718 1 Y 1 A GLY 1874 ? A GLY 1752 
719 1 Y 1 A TYR 1875 ? A TYR 1753 
720 1 Y 1 A SER 1876 ? A SER 1754 
721 1 Y 1 A LEU 1877 ? A LEU 1755 
722 1 Y 1 A TRP 1878 ? A TRP 1756 
723 1 Y 1 A VAL 1879 ? A VAL 1757 
724 1 Y 1 A GLN 1880 ? A GLN 1758 
725 1 Y 1 A ALA 1881 ? A ALA 1759 
726 1 Y 1 A HIS 1882 ? A HIS 1760 
727 1 Y 1 A ALA 1883 ? A ALA 1761 
728 1 Y 1 A THR 1884 ? A THR 1762 
729 1 Y 1 A PRO 1885 ? A PRO 1763 
730 1 Y 1 A THR 1886 ? A THR 1764 
731 1 Y 1 A LYS 1887 ? A LYS 1765 
732 1 Y 1 A SER 1888 ? A SER 1766 
733 1 Y 1 A ASN 1889 ? A ASN 1767 
734 1 Y 1 A SER 1890 ? A SER 1768 
735 1 Y 1 A SER 1891 ? A SER 1769 
736 1 Y 1 A GLU 1892 ? A GLU 1770 
737 1 Y 1 A ARG 1893 ? A ARG 1771 
738 1 Y 1 A LEU 1894 ? A LEU 1772 
739 1 Y 1 A HIS 1895 ? A HIS 1773 
740 1 Y 1 A VAL 1896 ? A VAL 1774 
741 1 Y 1 A ARG 1897 ? A ARG 1775 
742 1 Y 1 A SER 1898 ? A SER 1776 
743 1 Y 1 A PHE 1899 ? A PHE 1777 
744 1 Y 1 A ALA 1900 ? A ALA 1778 
745 1 Y 1 A GLU 1901 ? A GLU 1779 
746 1 Y 1 A LEU 1902 ? A LEU 1780 
747 1 Y 1 A PRO 1903 ? A PRO 1781 
748 1 Y 1 A GLU 1904 ? A GLU 1782 
749 1 Y 1 A LEU 1905 ? A LEU 1783 
750 1 Y 1 A GLN 1906 ? A GLN 1784 
751 1 Y 1 A LEU 1907 ? A LEU 1785 
752 1 Y 1 A LEU 1908 ? A LEU 1786 
753 1 Y 1 A GLU 1909 ? A GLU 1787 
754 1 Y 1 A LEU 1910 ? A LEU 1788 
755 1 Y 1 A GLY 1911 ? A GLY 1789 
756 1 Y 1 A PRO 1912 ? A PRO 1790 
757 1 Y 1 A TYR 1913 ? A TYR 1791 
758 1 Y 1 A SER 1914 ? A SER 1792 
759 1 Y 1 A LEU 1915 ? A LEU 1793 
760 1 Y 1 A SER 1916 ? A SER 1794 
761 1 Y 1 A LEU 1917 ? A LEU 1795 
762 1 Y 1 A THR 1918 ? A THR 1796 
763 1 Y 1 A TRP 1919 ? A TRP 1797 
764 1 Y 1 A ALA 1920 ? A ALA 1798 
765 1 Y 1 A GLY 1921 ? A GLY 1799 
766 1 Y 1 A THR 1922 ? A THR 1800 
767 1 Y 1 A PRO 1923 ? A PRO 1801 
768 1 Y 1 A ASP 1924 ? A ASP 1802 
769 1 Y 1 A PRO 1925 ? A PRO 1803 
770 1 Y 1 A LEU 1926 ? A LEU 1804 
771 1 Y 1 A GLY 1927 ? A GLY 1805 
772 1 Y 1 A SER 1928 ? A SER 1806 
773 1 Y 1 A LEU 1929 ? A LEU 1807 
774 1 Y 1 A GLN 1930 ? A GLN 1808 
775 1 Y 1 A LEU 1931 ? A LEU 1809 
776 1 Y 1 A GLU 1932 ? A GLU 1810 
777 1 Y 1 A CYS 1933 ? A CYS 1811 
778 1 Y 1 A ARG 1934 ? A ARG 1812 
779 1 Y 1 A SER 1935 ? A SER 1813 
780 1 Y 1 A SER 1936 ? A SER 1814 
781 1 Y 1 A ALA 1937 ? A ALA 1815 
782 1 Y 1 A GLU 1938 ? A GLU 1816 
783 1 Y 1 A GLN 1939 ? A GLN 1817 
784 1 Y 1 A LEU 1940 ? A LEU 1818 
785 1 Y 1 A ARG 1941 ? A ARG 1819 
786 1 Y 1 A ARG 1942 ? A ARG 1820 
787 1 Y 1 A ASN 1943 ? A ASN 1821 
788 1 Y 1 A VAL 1944 ? A VAL 1822 
789 1 Y 1 A ALA 1945 ? A ALA 1823 
790 1 Y 1 A GLY 1946 ? A GLY 1824 
791 1 Y 1 A ASN 1947 ? A ASN 1825 
792 1 Y 1 A HIS 1948 ? A HIS 1826 
793 1 Y 1 A THR 1949 ? A THR 1827 
794 1 Y 1 A LYS 1950 ? A LYS 1828 
795 1 Y 1 A MET 1951 ? A MET 1829 
796 1 Y 1 A VAL 1952 ? A VAL 1830 
797 1 Y 1 A VAL 1953 ? A VAL 1831 
798 1 Y 1 A GLU 1954 ? A GLU 1832 
799 1 Y 1 A PRO 1955 ? A PRO 1833 
800 1 Y 1 A LEU 1956 ? A LEU 1834 
801 1 Y 1 A GLN 1957 ? A GLN 1835 
802 1 Y 1 A PRO 1958 ? A PRO 1836 
803 1 Y 1 A ARG 1959 ? A ARG 1837 
804 1 Y 1 A THR 1960 ? A THR 1838 
805 1 Y 1 A ARG 1961 ? A ARG 1839 
806 1 Y 1 A TYR 1962 ? A TYR 1840 
807 1 Y 1 A GLN 1963 ? A GLN 1841 
808 1 Y 1 A CYS 1964 ? A CYS 1842 
809 1 Y 1 A ARG 1965 ? A ARG 1843 
810 1 Y 1 A LEU 1966 ? A LEU 1844 
811 1 Y 1 A LEU 1967 ? A LEU 1845 
812 1 Y 1 A LEU 1968 ? A LEU 1846 
813 1 Y 1 A GLY 1969 ? A GLY 1847 
814 1 Y 1 A TYR 1970 ? A TYR 1848 
815 1 Y 1 A ALA 1971 ? A ALA 1849 
816 1 Y 1 A ALA 1972 ? A ALA 1850 
817 1 Y 1 A THR 1973 ? A THR 1851 
818 1 Y 1 A PRO 1974 ? A PRO 1852 
819 1 Y 1 A GLY 1975 ? A GLY 1853 
820 1 Y 1 A ALA 1976 ? A ALA 1854 
821 1 Y 1 A PRO 1977 ? A PRO 1855 
822 1 Y 1 A LEU 1978 ? A LEU 1856 
823 1 Y 1 A TYR 1979 ? A TYR 1857 
824 1 Y 1 A HIS 1980 ? A HIS 1858 
825 1 Y 1 A GLY 1981 ? A GLY 1859 
826 1 Y 1 A THR 1982 ? A THR 1860 
827 1 Y 1 A ALA 1983 ? A ALA 1861 
828 1 Y 1 A GLU 1984 ? A GLU 1862 
829 1 Y 1 A VAL 1985 ? A VAL 1863 
830 1 Y 1 A TYR 1986 ? A TYR 1864 
831 1 Y 1 A GLU 1987 ? A GLU 1865 
832 1 Y 1 A THR 1988 ? A THR 1866 
833 1 Y 1 A LEU 1989 ? A LEU 1867 
834 1 Y 1 A GLY 1990 ? A GLY 1868 
835 1 Y 1 A ASP 1991 ? A ASP 1869 
836 1 Y 1 A ALA 1992 ? A ALA 1870 
837 1 Y 1 A PRO 1993 ? A PRO 1871 
838 1 Y 1 A SER 1994 ? A SER 1872 
839 1 Y 1 A GLN 1995 ? A GLN 1873 
840 1 Y 1 A PRO 1996 ? A PRO 1874 
841 1 Y 1 A GLY 1997 ? A GLY 1875 
842 1 Y 1 A LYS 1998 ? A LYS 1876 
843 1 Y 1 A PRO 1999 ? A PRO 1877 
844 1 Y 1 A GLN 2000 ? A GLN 1878 
845 1 Y 1 A LEU 2001 ? A LEU 1879 
846 1 Y 1 A GLU 2002 ? A GLU 1880 
847 1 Y 1 A HIS 2003 ? A HIS 1881 
848 1 Y 1 A ILE 2004 ? A ILE 1882 
849 1 Y 1 A ALA 2005 ? A ALA 1883 
850 1 Y 1 A GLU 2006 ? A GLU 1884 
851 1 Y 1 A GLU 2007 ? A GLU 1885 
852 1 Y 1 A VAL 2008 ? A VAL 1886 
853 1 Y 1 A PHE 2009 ? A PHE 1887 
854 1 Y 1 A ARG 2010 ? A ARG 1888 
855 1 Y 1 A VAL 2011 ? A VAL 1889 
856 1 Y 1 A THR 2012 ? A THR 1890 
857 1 Y 1 A TRP 2013 ? A TRP 1891 
858 1 Y 1 A THR 2014 ? A THR 1892 
859 1 Y 1 A ALA 2015 ? A ALA 1893 
860 1 Y 1 A ALA 2016 ? A ALA 1894 
861 1 Y 1 A ARG 2017 ? A ARG 1895 
862 1 Y 1 A GLY 2018 ? A GLY 1896 
863 1 Y 1 A ASN 2019 ? A ASN 1897 
864 1 Y 1 A GLY 2020 ? A GLY 1898 
865 1 Y 1 A ALA 2021 ? A ALA 1899 
866 1 Y 1 A PRO 2022 ? A PRO 1900 
867 1 Y 1 A ILE 2023 ? A ILE 1901 
868 1 Y 1 A ALA 2024 ? A ALA 1902 
869 1 Y 1 A LEU 2025 ? A LEU 1903 
870 1 Y 1 A TYR 2026 ? A TYR 1904 
871 1 Y 1 A ASN 2027 ? A ASN 1905 
872 1 Y 1 A LEU 2028 ? A LEU 1906 
873 1 Y 1 A GLU 2029 ? A GLU 1907 
874 1 Y 1 A ALA 2030 ? A ALA 1908 
875 1 Y 1 A LEU 2031 ? A LEU 1909 
876 1 Y 1 A GLN 2032 ? A GLN 1910 
877 1 Y 1 A ALA 2033 ? A ALA 1911 
878 1 Y 1 A ARG 2034 ? A ARG 1912 
879 1 Y 1 A SER 2035 ? A SER 1913 
880 1 Y 1 A ASP 2036 ? A ASP 1914 
881 1 Y 1 A ILE 2037 ? A ILE 1915 
882 1 Y 1 A ASN 2038 ? A ASN 1916 
883 1 Y 1 A SER 2039 ? A SER 1917 
884 1 Y 1 A GLY 2040 ? A GLY 1918 
885 1 Y 1 A GLY 2041 ? A GLY 1919 
886 1 Y 1 A SER 2042 ? A SER 1920 
887 1 Y 1 A LEU 2043 ? A LEU 1921 
888 1 Y 1 A GLU 2044 ? A GLU 1922 
889 1 Y 1 A GLN 2045 ? A GLN 1923 
890 1 Y 1 A LEU 2046 ? A LEU 1924 
891 1 Y 1 A PRO 2047 ? A PRO 1925 
892 1 Y 1 A TRP 2048 ? A TRP 1926 
893 1 Y 1 A ALA 2049 ? A ALA 1927 
894 1 Y 1 A GLU 2050 ? A GLU 1928 
895 1 Y 1 A GLU 2051 ? A GLU 1929 
896 1 Y 1 A PRO 2052 ? A PRO 1930 
897 1 Y 1 A VAL 2053 ? A VAL 1931 
898 1 Y 1 A VAL 2054 ? A VAL 1932 
899 1 Y 1 A VAL 2055 ? A VAL 1933 
900 1 Y 1 A GLU 2056 ? A GLU 1934 
901 1 Y 1 A ASP 2057 ? A ASP 1935 
902 1 Y 1 A GLN 2058 ? A GLN 1936 
903 1 Y 1 A TRP 2059 ? A TRP 1937 
904 1 Y 1 A LEU 2060 ? A LEU 1938 
905 1 Y 1 A ASP 2061 ? A ASP 1939 
906 1 Y 1 A PHE 2062 ? A PHE 1940 
907 1 Y 1 A CYS 2063 ? A CYS 1941 
908 1 Y 1 A ASN 2064 ? A ASN 1942 
909 1 Y 1 A THR 2065 ? A THR 1943 
910 1 Y 1 A THR 2066 ? A THR 1944 
911 1 Y 1 A GLU 2067 ? A GLU 1945 
912 1 Y 1 A LEU 2068 ? A LEU 1946 
913 1 Y 1 A SER 2069 ? A SER 1947 
914 1 Y 1 A CYS 2070 ? A CYS 1948 
915 1 Y 1 A ILE 2071 ? A ILE 1949 
916 1 Y 1 A VAL 2072 ? A VAL 1950 
917 1 Y 1 A LYS 2073 ? A LYS 1951 
918 1 Y 1 A SER 2074 ? A SER 1952 
919 1 Y 1 A LEU 2075 ? A LEU 1953 
920 1 Y 1 A HIS 2076 ? A HIS 1954 
921 1 Y 1 A SER 2077 ? A SER 1955 
922 1 Y 1 A SER 2078 ? A SER 1956 
923 1 Y 1 A ARG 2079 ? A ARG 1957 
924 1 Y 1 A LEU 2080 ? A LEU 1958 
925 1 Y 1 A LEU 2081 ? A LEU 1959 
926 1 Y 1 A LEU 2082 ? A LEU 1960 
927 1 Y 1 A PHE 2083 ? A PHE 1961 
928 1 Y 1 A ARG 2084 ? A ARG 1962 
929 1 Y 1 A VAL 2085 ? A VAL 1963 
930 1 Y 1 A ARG 2086 ? A ARG 1964 
931 1 Y 1 A ALA 2087 ? A ALA 1965 
932 1 Y 1 A ARG 2088 ? A ARG 1966 
933 1 Y 1 A SER 2089 ? A SER 1967 
934 1 Y 1 A LEU 2090 ? A LEU 1968 
935 1 Y 1 A GLU 2091 ? A GLU 1969 
936 1 Y 1 A HIS 2092 ? A HIS 1970 
937 1 Y 1 A GLY 2093 ? A GLY 1971 
938 1 Y 1 A TRP 2094 ? A TRP 1972 
939 1 Y 1 A GLY 2095 ? A GLY 1973 
940 1 Y 1 A PRO 2096 ? A PRO 1974 
941 1 Y 1 A TYR 2097 ? A TYR 1975 
942 1 Y 1 A SER 2098 ? A SER 1976 
943 1 Y 1 A GLU 2099 ? A GLU 1977 
944 1 Y 1 A GLU 2100 ? A GLU 1978 
945 1 Y 1 A SER 2101 ? A SER 1979 
946 1 Y 1 A GLU 2102 ? A GLU 1980 
947 1 Y 1 A ARG 2103 ? A ARG 1981 
948 1 Y 1 A VAL 2104 ? A VAL 1982 
949 1 Y 1 A ALA 2105 ? A ALA 1983 
950 1 Y 1 A GLU 2106 ? A GLU 1984 
951 1 Y 1 A PRO 2107 ? A PRO 1985 
952 1 Y 1 A PHE 2108 ? A PHE 1986 
953 1 Y 1 A VAL 2109 ? A VAL 1987 
954 1 Y 1 A SER 2110 ? A SER 1988 
955 1 Y 1 A HIS 2111 ? A HIS 1989 
956 1 Y 1 A HIS 2112 ? A HIS 1990 
957 1 Y 1 A HIS 2113 ? A HIS 1991 
958 1 Y 1 A HIS 2114 ? A HIS 1992 
959 1 Y 1 A HIS 2115 ? A HIS 1993 
960 1 Y 1 A HIS 2116 ? A HIS 1994 
961 1 Y 1 A TRP 2117 ? A TRP 1995 
962 1 Y 1 A SER 2118 ? A SER 1996 
963 1 Y 1 A HIS 2119 ? A HIS 1997 
964 1 Y 1 A PRO 2120 ? A PRO 1998 
965 1 Y 1 A GLN 2121 ? A GLN 1999 
966 1 Y 1 A PHE 2122 ? A PHE 2000 
967 1 Y 1 A GLU 2123 ? A GLU 2001 
968 1 Y 1 A LYS 2124 ? A LYS 2002 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
CYS N    N N N 74  
CYS CA   C N R 75  
CYS C    C N N 76  
CYS O    O N N 77  
CYS CB   C N N 78  
CYS SG   S N N 79  
CYS OXT  O N N 80  
CYS H    H N N 81  
CYS H2   H N N 82  
CYS HA   H N N 83  
CYS HB2  H N N 84  
CYS HB3  H N N 85  
CYS HG   H N N 86  
CYS HXT  H N N 87  
GLN N    N N N 88  
GLN CA   C N S 89  
GLN C    C N N 90  
GLN O    O N N 91  
GLN CB   C N N 92  
GLN CG   C N N 93  
GLN CD   C N N 94  
GLN OE1  O N N 95  
GLN NE2  N N N 96  
GLN OXT  O N N 97  
GLN H    H N N 98  
GLN H2   H N N 99  
GLN HA   H N N 100 
GLN HB2  H N N 101 
GLN HB3  H N N 102 
GLN HG2  H N N 103 
GLN HG3  H N N 104 
GLN HE21 H N N 105 
GLN HE22 H N N 106 
GLN HXT  H N N 107 
GLU N    N N N 108 
GLU CA   C N S 109 
GLU C    C N N 110 
GLU O    O N N 111 
GLU CB   C N N 112 
GLU CG   C N N 113 
GLU CD   C N N 114 
GLU OE1  O N N 115 
GLU OE2  O N N 116 
GLU OXT  O N N 117 
GLU H    H N N 118 
GLU H2   H N N 119 
GLU HA   H N N 120 
GLU HB2  H N N 121 
GLU HB3  H N N 122 
GLU HG2  H N N 123 
GLU HG3  H N N 124 
GLU HE2  H N N 125 
GLU HXT  H N N 126 
GLY N    N N N 127 
GLY CA   C N N 128 
GLY C    C N N 129 
GLY O    O N N 130 
GLY OXT  O N N 131 
GLY H    H N N 132 
GLY H2   H N N 133 
GLY HA2  H N N 134 
GLY HA3  H N N 135 
GLY HXT  H N N 136 
HIS N    N N N 137 
HIS CA   C N S 138 
HIS C    C N N 139 
HIS O    O N N 140 
HIS CB   C N N 141 
HIS CG   C Y N 142 
HIS ND1  N Y N 143 
HIS CD2  C Y N 144 
HIS CE1  C Y N 145 
HIS NE2  N Y N 146 
HIS OXT  O N N 147 
HIS H    H N N 148 
HIS H2   H N N 149 
HIS HA   H N N 150 
HIS HB2  H N N 151 
HIS HB3  H N N 152 
HIS HD1  H N N 153 
HIS HD2  H N N 154 
HIS HE1  H N N 155 
HIS HE2  H N N 156 
HIS HXT  H N N 157 
ILE N    N N N 158 
ILE CA   C N S 159 
ILE C    C N N 160 
ILE O    O N N 161 
ILE CB   C N S 162 
ILE CG1  C N N 163 
ILE CG2  C N N 164 
ILE CD1  C N N 165 
ILE OXT  O N N 166 
ILE H    H N N 167 
ILE H2   H N N 168 
ILE HA   H N N 169 
ILE HB   H N N 170 
ILE HG12 H N N 171 
ILE HG13 H N N 172 
ILE HG21 H N N 173 
ILE HG22 H N N 174 
ILE HG23 H N N 175 
ILE HD11 H N N 176 
ILE HD12 H N N 177 
ILE HD13 H N N 178 
ILE HXT  H N N 179 
LEU N    N N N 180 
LEU CA   C N S 181 
LEU C    C N N 182 
LEU O    O N N 183 
LEU CB   C N N 184 
LEU CG   C N N 185 
LEU CD1  C N N 186 
LEU CD2  C N N 187 
LEU OXT  O N N 188 
LEU H    H N N 189 
LEU H2   H N N 190 
LEU HA   H N N 191 
LEU HB2  H N N 192 
LEU HB3  H N N 193 
LEU HG   H N N 194 
LEU HD11 H N N 195 
LEU HD12 H N N 196 
LEU HD13 H N N 197 
LEU HD21 H N N 198 
LEU HD22 H N N 199 
LEU HD23 H N N 200 
LEU HXT  H N N 201 
LYS N    N N N 202 
LYS CA   C N S 203 
LYS C    C N N 204 
LYS O    O N N 205 
LYS CB   C N N 206 
LYS CG   C N N 207 
LYS CD   C N N 208 
LYS CE   C N N 209 
LYS NZ   N N N 210 
LYS OXT  O N N 211 
LYS H    H N N 212 
LYS H2   H N N 213 
LYS HA   H N N 214 
LYS HB2  H N N 215 
LYS HB3  H N N 216 
LYS HG2  H N N 217 
LYS HG3  H N N 218 
LYS HD2  H N N 219 
LYS HD3  H N N 220 
LYS HE2  H N N 221 
LYS HE3  H N N 222 
LYS HZ1  H N N 223 
LYS HZ2  H N N 224 
LYS HZ3  H N N 225 
LYS HXT  H N N 226 
MET N    N N N 227 
MET CA   C N S 228 
MET C    C N N 229 
MET O    O N N 230 
MET CB   C N N 231 
MET CG   C N N 232 
MET SD   S N N 233 
MET CE   C N N 234 
MET OXT  O N N 235 
MET H    H N N 236 
MET H2   H N N 237 
MET HA   H N N 238 
MET HB2  H N N 239 
MET HB3  H N N 240 
MET HG2  H N N 241 
MET HG3  H N N 242 
MET HE1  H N N 243 
MET HE2  H N N 244 
MET HE3  H N N 245 
MET HXT  H N N 246 
NAG C1   C N R 247 
NAG C2   C N R 248 
NAG C3   C N R 249 
NAG C4   C N S 250 
NAG C5   C N R 251 
NAG C6   C N N 252 
NAG C7   C N N 253 
NAG C8   C N N 254 
NAG N2   N N N 255 
NAG O1   O N N 256 
NAG O3   O N N 257 
NAG O4   O N N 258 
NAG O5   O N N 259 
NAG O6   O N N 260 
NAG O7   O N N 261 
NAG H1   H N N 262 
NAG H2   H N N 263 
NAG H3   H N N 264 
NAG H4   H N N 265 
NAG H5   H N N 266 
NAG H61  H N N 267 
NAG H62  H N N 268 
NAG H81  H N N 269 
NAG H82  H N N 270 
NAG H83  H N N 271 
NAG HN2  H N N 272 
NAG HO1  H N N 273 
NAG HO3  H N N 274 
NAG HO4  H N N 275 
NAG HO6  H N N 276 
PHE N    N N N 277 
PHE CA   C N S 278 
PHE C    C N N 279 
PHE O    O N N 280 
PHE CB   C N N 281 
PHE CG   C Y N 282 
PHE CD1  C Y N 283 
PHE CD2  C Y N 284 
PHE CE1  C Y N 285 
PHE CE2  C Y N 286 
PHE CZ   C Y N 287 
PHE OXT  O N N 288 
PHE H    H N N 289 
PHE H2   H N N 290 
PHE HA   H N N 291 
PHE HB2  H N N 292 
PHE HB3  H N N 293 
PHE HD1  H N N 294 
PHE HD2  H N N 295 
PHE HE1  H N N 296 
PHE HE2  H N N 297 
PHE HZ   H N N 298 
PHE HXT  H N N 299 
PRO N    N N N 300 
PRO CA   C N S 301 
PRO C    C N N 302 
PRO O    O N N 303 
PRO CB   C N N 304 
PRO CG   C N N 305 
PRO CD   C N N 306 
PRO OXT  O N N 307 
PRO H    H N N 308 
PRO HA   H N N 309 
PRO HB2  H N N 310 
PRO HB3  H N N 311 
PRO HG2  H N N 312 
PRO HG3  H N N 313 
PRO HD2  H N N 314 
PRO HD3  H N N 315 
PRO HXT  H N N 316 
SER N    N N N 317 
SER CA   C N S 318 
SER C    C N N 319 
SER O    O N N 320 
SER CB   C N N 321 
SER OG   O N N 322 
SER OXT  O N N 323 
SER H    H N N 324 
SER H2   H N N 325 
SER HA   H N N 326 
SER HB2  H N N 327 
SER HB3  H N N 328 
SER HG   H N N 329 
SER HXT  H N N 330 
THR N    N N N 331 
THR CA   C N S 332 
THR C    C N N 333 
THR O    O N N 334 
THR CB   C N R 335 
THR OG1  O N N 336 
THR CG2  C N N 337 
THR OXT  O N N 338 
THR H    H N N 339 
THR H2   H N N 340 
THR HA   H N N 341 
THR HB   H N N 342 
THR HG1  H N N 343 
THR HG21 H N N 344 
THR HG22 H N N 345 
THR HG23 H N N 346 
THR HXT  H N N 347 
TRP N    N N N 348 
TRP CA   C N S 349 
TRP C    C N N 350 
TRP O    O N N 351 
TRP CB   C N N 352 
TRP CG   C Y N 353 
TRP CD1  C Y N 354 
TRP CD2  C Y N 355 
TRP NE1  N Y N 356 
TRP CE2  C Y N 357 
TRP CE3  C Y N 358 
TRP CZ2  C Y N 359 
TRP CZ3  C Y N 360 
TRP CH2  C Y N 361 
TRP OXT  O N N 362 
TRP H    H N N 363 
TRP H2   H N N 364 
TRP HA   H N N 365 
TRP HB2  H N N 366 
TRP HB3  H N N 367 
TRP HD1  H N N 368 
TRP HE1  H N N 369 
TRP HE3  H N N 370 
TRP HZ2  H N N 371 
TRP HZ3  H N N 372 
TRP HH2  H N N 373 
TRP HXT  H N N 374 
TYR N    N N N 375 
TYR CA   C N S 376 
TYR C    C N N 377 
TYR O    O N N 378 
TYR CB   C N N 379 
TYR CG   C Y N 380 
TYR CD1  C Y N 381 
TYR CD2  C Y N 382 
TYR CE1  C Y N 383 
TYR CE2  C Y N 384 
TYR CZ   C Y N 385 
TYR OH   O N N 386 
TYR OXT  O N N 387 
TYR H    H N N 388 
TYR H2   H N N 389 
TYR HA   H N N 390 
TYR HB2  H N N 391 
TYR HB3  H N N 392 
TYR HD1  H N N 393 
TYR HD2  H N N 394 
TYR HE1  H N N 395 
TYR HE2  H N N 396 
TYR HH   H N N 397 
TYR HXT  H N N 398 
VAL N    N N N 399 
VAL CA   C N S 400 
VAL C    C N N 401 
VAL O    O N N 402 
VAL CB   C N N 403 
VAL CG1  C N N 404 
VAL CG2  C N N 405 
VAL OXT  O N N 406 
VAL H    H N N 407 
VAL H2   H N N 408 
VAL HA   H N N 409 
VAL HB   H N N 410 
VAL HG11 H N N 411 
VAL HG12 H N N 412 
VAL HG13 H N N 413 
VAL HG21 H N N 414 
VAL HG22 H N N 415 
VAL HG23 H N N 416 
VAL HXT  H N N 417 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
ILE N   CA   sing N N 150 
ILE N   H    sing N N 151 
ILE N   H2   sing N N 152 
ILE CA  C    sing N N 153 
ILE CA  CB   sing N N 154 
ILE CA  HA   sing N N 155 
ILE C   O    doub N N 156 
ILE C   OXT  sing N N 157 
ILE CB  CG1  sing N N 158 
ILE CB  CG2  sing N N 159 
ILE CB  HB   sing N N 160 
ILE CG1 CD1  sing N N 161 
ILE CG1 HG12 sing N N 162 
ILE CG1 HG13 sing N N 163 
ILE CG2 HG21 sing N N 164 
ILE CG2 HG22 sing N N 165 
ILE CG2 HG23 sing N N 166 
ILE CD1 HD11 sing N N 167 
ILE CD1 HD12 sing N N 168 
ILE CD1 HD13 sing N N 169 
ILE OXT HXT  sing N N 170 
LEU N   CA   sing N N 171 
LEU N   H    sing N N 172 
LEU N   H2   sing N N 173 
LEU CA  C    sing N N 174 
LEU CA  CB   sing N N 175 
LEU CA  HA   sing N N 176 
LEU C   O    doub N N 177 
LEU C   OXT  sing N N 178 
LEU CB  CG   sing N N 179 
LEU CB  HB2  sing N N 180 
LEU CB  HB3  sing N N 181 
LEU CG  CD1  sing N N 182 
LEU CG  CD2  sing N N 183 
LEU CG  HG   sing N N 184 
LEU CD1 HD11 sing N N 185 
LEU CD1 HD12 sing N N 186 
LEU CD1 HD13 sing N N 187 
LEU CD2 HD21 sing N N 188 
LEU CD2 HD22 sing N N 189 
LEU CD2 HD23 sing N N 190 
LEU OXT HXT  sing N N 191 
LYS N   CA   sing N N 192 
LYS N   H    sing N N 193 
LYS N   H2   sing N N 194 
LYS CA  C    sing N N 195 
LYS CA  CB   sing N N 196 
LYS CA  HA   sing N N 197 
LYS C   O    doub N N 198 
LYS C   OXT  sing N N 199 
LYS CB  CG   sing N N 200 
LYS CB  HB2  sing N N 201 
LYS CB  HB3  sing N N 202 
LYS CG  CD   sing N N 203 
LYS CG  HG2  sing N N 204 
LYS CG  HG3  sing N N 205 
LYS CD  CE   sing N N 206 
LYS CD  HD2  sing N N 207 
LYS CD  HD3  sing N N 208 
LYS CE  NZ   sing N N 209 
LYS CE  HE2  sing N N 210 
LYS CE  HE3  sing N N 211 
LYS NZ  HZ1  sing N N 212 
LYS NZ  HZ2  sing N N 213 
LYS NZ  HZ3  sing N N 214 
LYS OXT HXT  sing N N 215 
MET N   CA   sing N N 216 
MET N   H    sing N N 217 
MET N   H2   sing N N 218 
MET CA  C    sing N N 219 
MET CA  CB   sing N N 220 
MET CA  HA   sing N N 221 
MET C   O    doub N N 222 
MET C   OXT  sing N N 223 
MET CB  CG   sing N N 224 
MET CB  HB2  sing N N 225 
MET CB  HB3  sing N N 226 
MET CG  SD   sing N N 227 
MET CG  HG2  sing N N 228 
MET CG  HG3  sing N N 229 
MET SD  CE   sing N N 230 
MET CE  HE1  sing N N 231 
MET CE  HE2  sing N N 232 
MET CE  HE3  sing N N 233 
MET OXT HXT  sing N N 234 
NAG C1  C2   sing N N 235 
NAG C1  O1   sing N N 236 
NAG C1  O5   sing N N 237 
NAG C1  H1   sing N N 238 
NAG C2  C3   sing N N 239 
NAG C2  N2   sing N N 240 
NAG C2  H2   sing N N 241 
NAG C3  C4   sing N N 242 
NAG C3  O3   sing N N 243 
NAG C3  H3   sing N N 244 
NAG C4  C5   sing N N 245 
NAG C4  O4   sing N N 246 
NAG C4  H4   sing N N 247 
NAG C5  C6   sing N N 248 
NAG C5  O5   sing N N 249 
NAG C5  H5   sing N N 250 
NAG C6  O6   sing N N 251 
NAG C6  H61  sing N N 252 
NAG C6  H62  sing N N 253 
NAG C7  C8   sing N N 254 
NAG C7  N2   sing N N 255 
NAG C7  O7   doub N N 256 
NAG C8  H81  sing N N 257 
NAG C8  H82  sing N N 258 
NAG C8  H83  sing N N 259 
NAG N2  HN2  sing N N 260 
NAG O1  HO1  sing N N 261 
NAG O3  HO3  sing N N 262 
NAG O4  HO4  sing N N 263 
NAG O6  HO6  sing N N 264 
PHE N   CA   sing N N 265 
PHE N   H    sing N N 266 
PHE N   H2   sing N N 267 
PHE CA  C    sing N N 268 
PHE CA  CB   sing N N 269 
PHE CA  HA   sing N N 270 
PHE C   O    doub N N 271 
PHE C   OXT  sing N N 272 
PHE CB  CG   sing N N 273 
PHE CB  HB2  sing N N 274 
PHE CB  HB3  sing N N 275 
PHE CG  CD1  doub Y N 276 
PHE CG  CD2  sing Y N 277 
PHE CD1 CE1  sing Y N 278 
PHE CD1 HD1  sing N N 279 
PHE CD2 CE2  doub Y N 280 
PHE CD2 HD2  sing N N 281 
PHE CE1 CZ   doub Y N 282 
PHE CE1 HE1  sing N N 283 
PHE CE2 CZ   sing Y N 284 
PHE CE2 HE2  sing N N 285 
PHE CZ  HZ   sing N N 286 
PHE OXT HXT  sing N N 287 
PRO N   CA   sing N N 288 
PRO N   CD   sing N N 289 
PRO N   H    sing N N 290 
PRO CA  C    sing N N 291 
PRO CA  CB   sing N N 292 
PRO CA  HA   sing N N 293 
PRO C   O    doub N N 294 
PRO C   OXT  sing N N 295 
PRO CB  CG   sing N N 296 
PRO CB  HB2  sing N N 297 
PRO CB  HB3  sing N N 298 
PRO CG  CD   sing N N 299 
PRO CG  HG2  sing N N 300 
PRO CG  HG3  sing N N 301 
PRO CD  HD2  sing N N 302 
PRO CD  HD3  sing N N 303 
PRO OXT HXT  sing N N 304 
SER N   CA   sing N N 305 
SER N   H    sing N N 306 
SER N   H2   sing N N 307 
SER CA  C    sing N N 308 
SER CA  CB   sing N N 309 
SER CA  HA   sing N N 310 
SER C   O    doub N N 311 
SER C   OXT  sing N N 312 
SER CB  OG   sing N N 313 
SER CB  HB2  sing N N 314 
SER CB  HB3  sing N N 315 
SER OG  HG   sing N N 316 
SER OXT HXT  sing N N 317 
THR N   CA   sing N N 318 
THR N   H    sing N N 319 
THR N   H2   sing N N 320 
THR CA  C    sing N N 321 
THR CA  CB   sing N N 322 
THR CA  HA   sing N N 323 
THR C   O    doub N N 324 
THR C   OXT  sing N N 325 
THR CB  OG1  sing N N 326 
THR CB  CG2  sing N N 327 
THR CB  HB   sing N N 328 
THR OG1 HG1  sing N N 329 
THR CG2 HG21 sing N N 330 
THR CG2 HG22 sing N N 331 
THR CG2 HG23 sing N N 332 
THR OXT HXT  sing N N 333 
TRP N   CA   sing N N 334 
TRP N   H    sing N N 335 
TRP N   H2   sing N N 336 
TRP CA  C    sing N N 337 
TRP CA  CB   sing N N 338 
TRP CA  HA   sing N N 339 
TRP C   O    doub N N 340 
TRP C   OXT  sing N N 341 
TRP CB  CG   sing N N 342 
TRP CB  HB2  sing N N 343 
TRP CB  HB3  sing N N 344 
TRP CG  CD1  doub Y N 345 
TRP CG  CD2  sing Y N 346 
TRP CD1 NE1  sing Y N 347 
TRP CD1 HD1  sing N N 348 
TRP CD2 CE2  doub Y N 349 
TRP CD2 CE3  sing Y N 350 
TRP NE1 CE2  sing Y N 351 
TRP NE1 HE1  sing N N 352 
TRP CE2 CZ2  sing Y N 353 
TRP CE3 CZ3  doub Y N 354 
TRP CE3 HE3  sing N N 355 
TRP CZ2 CH2  doub Y N 356 
TRP CZ2 HZ2  sing N N 357 
TRP CZ3 CH2  sing Y N 358 
TRP CZ3 HZ3  sing N N 359 
TRP CH2 HH2  sing N N 360 
TRP OXT HXT  sing N N 361 
TYR N   CA   sing N N 362 
TYR N   H    sing N N 363 
TYR N   H2   sing N N 364 
TYR CA  C    sing N N 365 
TYR CA  CB   sing N N 366 
TYR CA  HA   sing N N 367 
TYR C   O    doub N N 368 
TYR C   OXT  sing N N 369 
TYR CB  CG   sing N N 370 
TYR CB  HB2  sing N N 371 
TYR CB  HB3  sing N N 372 
TYR CG  CD1  doub Y N 373 
TYR CG  CD2  sing Y N 374 
TYR CD1 CE1  sing Y N 375 
TYR CD1 HD1  sing N N 376 
TYR CD2 CE2  doub Y N 377 
TYR CD2 HD2  sing N N 378 
TYR CE1 CZ   doub Y N 379 
TYR CE1 HE1  sing N N 380 
TYR CE2 CZ   sing Y N 381 
TYR CE2 HE2  sing N N 382 
TYR CZ  OH   sing N N 383 
TYR OH  HH   sing N N 384 
TYR OXT HXT  sing N N 385 
VAL N   CA   sing N N 386 
VAL N   H    sing N N 387 
VAL N   H2   sing N N 388 
VAL CA  C    sing N N 389 
VAL CA  CB   sing N N 390 
VAL CA  HA   sing N N 391 
VAL C   O    doub N N 392 
VAL C   OXT  sing N N 393 
VAL CB  CG1  sing N N 394 
VAL CB  CG2  sing N N 395 
VAL CB  HB   sing N N 396 
VAL CG1 HG11 sing N N 397 
VAL CG1 HG12 sing N N 398 
VAL CG1 HG13 sing N N 399 
VAL CG2 HG21 sing N N 400 
VAL CG2 HG22 sing N N 401 
VAL CG2 HG23 sing N N 402 
VAL OXT HXT  sing N N 403 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-18 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BFP 
_em_admin.last_update        2025-05-14 
_em_admin.map_release_date   2025-01-29 
_em_admin.title              'Cryo-EM structure of Sevenless extracellular domain (monomer)' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          7227 
_em_entity_assembly_naturalsource.organism             'Drosophila melanogaster' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7227 
_em_entity_assembly_recombinant.organism             'Drosophila melanogaster' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         51.8 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   'Other private' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           ? 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 NAG 1 n 
2 NAG 2 n 
# 
_atom_sites.entry_id                    9BFP 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY A 1 84   ? 160.357 119.073 185.567 1.00 116.55 ? 206  GLY A N   1 
ATOM   2    C CA  . GLY A 1 84   ? 161.713 118.575 185.437 1.00 120.08 ? 206  GLY A CA  1 
ATOM   3    C C   . GLY A 1 84   ? 162.724 119.393 186.216 1.00 119.94 ? 206  GLY A C   1 
ATOM   4    O O   . GLY A 1 84   ? 162.356 120.275 186.990 1.00 118.27 ? 206  GLY A O   1 
ATOM   5    N N   . VAL A 1 85   ? 164.008 119.096 186.011 1.00 121.66 ? 207  VAL A N   1 
ATOM   6    C CA  . VAL A 1 85   ? 165.059 119.842 186.698 1.00 122.95 ? 207  VAL A CA  1 
ATOM   7    C C   . VAL A 1 85   ? 165.347 121.149 185.971 1.00 120.72 ? 207  VAL A C   1 
ATOM   8    O O   . VAL A 1 85   ? 165.905 122.089 186.550 1.00 117.57 ? 207  VAL A O   1 
ATOM   9    C CB  . VAL A 1 85   ? 166.326 118.979 186.843 1.00 125.98 ? 207  VAL A CB  1 
ATOM   10   C CG1 . VAL A 1 85   ? 166.133 117.938 187.933 1.00 124.80 ? 207  VAL A CG1 1 
ATOM   11   C CG2 . VAL A 1 85   ? 166.674 118.311 185.521 1.00 123.36 ? 207  VAL A CG2 1 
ATOM   12   N N   . ASP A 1 86   ? 164.981 121.229 184.689 1.00 120.20 ? 208  ASP A N   1 
ATOM   13   C CA  . ASP A 1 86   ? 165.128 122.479 183.954 1.00 120.51 ? 208  ASP A CA  1 
ATOM   14   C C   . ASP A 1 86   ? 164.029 123.467 184.327 1.00 115.21 ? 208  ASP A C   1 
ATOM   15   O O   . ASP A 1 86   ? 164.210 124.682 184.202 1.00 112.07 ? 208  ASP A O   1 
ATOM   16   C CB  . ASP A 1 86   ? 165.121 122.208 182.449 1.00 122.09 ? 208  ASP A CB  1 
ATOM   17   C CG  . ASP A 1 86   ? 165.641 123.381 181.642 1.00 123.99 ? 208  ASP A CG  1 
ATOM   18   O OD1 . ASP A 1 86   ? 166.400 124.200 182.202 1.00 120.15 ? 208  ASP A OD1 1 
ATOM   19   O OD2 . ASP A 1 86   ? 165.290 123.485 180.447 1.00 126.23 ? 208  ASP A OD2 1 
ATOM   20   N N   . GLU A 1 87   ? 162.880 122.960 184.779 1.00 113.48 ? 209  GLU A N   1 
ATOM   21   C CA  . GLU A 1 87   ? 161.773 123.828 185.172 1.00 109.46 ? 209  GLU A CA  1 
ATOM   22   C C   . GLU A 1 87   ? 162.037 124.487 186.524 1.00 107.70 ? 209  GLU A C   1 
ATOM   23   O O   . GLU A 1 87   ? 161.739 125.677 186.712 1.00 104.99 ? 209  GLU A O   1 
ATOM   24   C CB  . GLU A 1 87   ? 160.472 123.012 185.176 1.00 110.10 ? 209  GLU A CB  1 
ATOM   25   C CG  . GLU A 1 87   ? 159.272 123.588 185.940 1.00 111.38 ? 209  GLU A CG  1 
ATOM   26   C CD  . GLU A 1 87   ? 158.391 124.514 185.106 1.00 107.74 ? 209  GLU A CD  1 
ATOM   27   O OE1 . GLU A 1 87   ? 158.820 124.974 184.026 1.00 104.36 ? 209  GLU A OE1 1 
ATOM   28   O OE2 . GLU A 1 87   ? 157.249 124.777 185.536 1.00 105.62 ? 209  GLU A OE2 1 
ATOM   29   N N   . ARG A 1 88   ? 162.655 123.742 187.452 1.00 108.70 ? 210  ARG A N   1 
ATOM   30   C CA  . ARG A 1 88   ? 162.858 124.219 188.821 1.00 104.90 ? 210  ARG A CA  1 
ATOM   31   C C   . ARG A 1 88   ? 163.945 125.285 188.893 1.00 101.74 ? 210  ARG A C   1 
ATOM   32   O O   . ARG A 1 88   ? 163.902 126.157 189.769 1.00 101.96 ? 210  ARG A O   1 
ATOM   33   C CB  . ARG A 1 88   ? 163.212 123.050 189.737 1.00 109.01 ? 210  ARG A CB  1 
ATOM   34   C CG  . ARG A 1 88   ? 162.106 122.026 189.920 1.00 112.64 ? 210  ARG A CG  1 
ATOM   35   C CD  . ARG A 1 88   ? 160.830 122.646 190.462 1.00 112.90 ? 210  ARG A CD  1 
ATOM   36   N NE  . ARG A 1 88   ? 159.648 121.958 189.957 1.00 117.08 ? 210  ARG A NE  1 
ATOM   37   C CZ  . ARG A 1 88   ? 158.406 122.217 190.343 1.00 117.02 ? 210  ARG A CZ  1 
ATOM   38   N NH1 . ARG A 1 88   ? 158.145 123.141 191.253 1.00 115.79 ? 210  ARG A NH1 1 
ATOM   39   N NH2 . ARG A 1 88   ? 157.404 121.529 189.806 1.00 113.56 ? 210  ARG A NH2 1 
ATOM   40   N N   . MET A 1 89   ? 164.895 125.257 187.951 1.00 102.95 ? 211  MET A N   1 
ATOM   41   C CA  . MET A 1 89   ? 165.890 126.323 187.846 1.00 102.54 ? 211  MET A CA  1 
ATOM   42   C C   . MET A 1 89   ? 165.262 127.619 187.343 1.00 95.93  ? 211  MET A C   1 
ATOM   43   O O   . MET A 1 89   ? 165.637 128.708 187.792 1.00 95.15  ? 211  MET A O   1 
ATOM   44   C CB  . MET A 1 89   ? 167.028 125.894 186.918 1.00 107.30 ? 211  MET A CB  1 
ATOM   45   C CG  . MET A 1 89   ? 167.896 124.715 187.386 1.00 114.49 ? 211  MET A CG  1 
ATOM   46   S SD  . MET A 1 89   ? 168.821 124.918 188.929 1.00 121.90 ? 211  MET A SD  1 
ATOM   47   C CE  . MET A 1 89   ? 167.834 123.978 190.101 1.00 111.03 ? 211  MET A CE  1 
ATOM   48   N N   . VAL A 1 90   ? 164.268 127.505 186.452 1.00 94.05  ? 212  VAL A N   1 
ATOM   49   C CA  . VAL A 1 90   ? 163.536 128.661 185.936 1.00 89.67  ? 212  VAL A CA  1 
ATOM   50   C C   . VAL A 1 90   ? 162.647 129.266 187.024 1.00 89.66  ? 212  VAL A C   1 
ATOM   51   O O   . VAL A 1 90   ? 162.614 130.495 187.198 1.00 90.83  ? 212  VAL A O   1 
ATOM   52   C CB  . VAL A 1 90   ? 162.743 128.245 184.675 1.00 88.18  ? 212  VAL A CB  1 
ATOM   53   C CG1 . VAL A 1 90   ? 161.748 129.300 184.216 1.00 78.08  ? 212  VAL A CG1 1 
ATOM   54   C CG2 . VAL A 1 90   ? 163.703 127.953 183.543 1.00 94.88  ? 212  VAL A CG2 1 
ATOM   55   N N   . LEU A 1 91   ? 161.991 128.405 187.823 1.00 90.90  ? 213  LEU A N   1 
ATOM   56   C CA  . LEU A 1 91   ? 161.180 128.848 188.964 1.00 86.54  ? 213  LEU A CA  1 
ATOM   57   C C   . LEU A 1 91   ? 162.017 129.485 190.073 1.00 84.66  ? 213  LEU A C   1 
ATOM   58   O O   . LEU A 1 91   ? 161.618 130.508 190.644 1.00 87.09  ? 213  LEU A O   1 
ATOM   59   C CB  . LEU A 1 91   ? 160.371 127.681 189.531 1.00 87.05  ? 213  LEU A CB  1 
ATOM   60   C CG  . LEU A 1 91   ? 158.927 127.460 189.079 1.00 87.68  ? 213  LEU A CG  1 
ATOM   61   C CD1 . LEU A 1 91   ? 158.801 127.055 187.634 1.00 88.74  ? 213  LEU A CD1 1 
ATOM   62   C CD2 . LEU A 1 91   ? 158.284 126.419 189.977 1.00 91.21  ? 213  LEU A CD2 1 
ATOM   63   N N   . GLU A 1 92   ? 163.206 128.927 190.346 1.00 84.77  ? 214  GLU A N   1 
ATOM   64   C CA  . GLU A 1 92   ? 164.086 129.494 191.364 1.00 83.85  ? 214  GLU A CA  1 
ATOM   65   C C   . GLU A 1 92   ? 164.726 130.798 190.901 1.00 85.37  ? 214  GLU A C   1 
ATOM   66   O O   . GLU A 1 92   ? 164.895 131.718 191.709 1.00 90.90  ? 214  GLU A O   1 
ATOM   67   C CB  . GLU A 1 92   ? 165.161 128.483 191.757 1.00 91.62  ? 214  GLU A CB  1 
ATOM   68   C CG  . GLU A 1 92   ? 164.700 127.461 192.785 1.00 97.85  ? 214  GLU A CG  1 
ATOM   69   C CD  . GLU A 1 92   ? 165.727 126.372 193.025 1.00 104.82 ? 214  GLU A CD  1 
ATOM   70   O OE1 . GLU A 1 92   ? 166.743 126.343 192.301 1.00 106.36 ? 214  GLU A OE1 1 
ATOM   71   O OE2 . GLU A 1 92   ? 165.517 125.544 193.936 1.00 103.89 ? 214  GLU A OE2 1 
ATOM   72   N N   . ARG A 1 93   ? 165.022 130.917 189.596 1.00 82.39  ? 215  ARG A N   1 
ATOM   73   C CA  . ARG A 1 93   ? 165.588 132.151 189.052 1.00 81.20  ? 215  ARG A CA  1 
ATOM   74   C C   . ARG A 1 93   ? 164.563 133.279 189.016 1.00 81.90  ? 215  ARG A C   1 
ATOM   75   O O   . ARG A 1 93   ? 164.888 134.423 189.358 1.00 86.01  ? 215  ARG A O   1 
ATOM   76   C CB  . ARG A 1 93   ? 166.141 131.897 187.650 1.00 84.36  ? 215  ARG A CB  1 
ATOM   77   C CG  . ARG A 1 93   ? 166.956 133.049 187.082 1.00 86.72  ? 215  ARG A CG  1 
ATOM   78   C CD  . ARG A 1 93   ? 167.249 132.853 185.607 1.00 87.75  ? 215  ARG A CD  1 
ATOM   79   N NE  . ARG A 1 93   ? 167.482 131.454 185.275 1.00 94.57  ? 215  ARG A NE  1 
ATOM   80   C CZ  . ARG A 1 93   ? 167.714 131.005 184.049 1.00 93.83  ? 215  ARG A CZ  1 
ATOM   81   N NH1 . ARG A 1 93   ? 167.758 131.822 183.011 1.00 91.19  ? 215  ARG A NH1 1 
ATOM   82   N NH2 . ARG A 1 93   ? 167.903 129.702 183.861 1.00 89.88  ? 215  ARG A NH2 1 
ATOM   83   N N   . VAL A 1 94   ? 163.314 132.957 188.652 1.00 77.96  ? 216  VAL A N   1 
ATOM   84   C CA  . VAL A 1 94   ? 162.241 133.951 188.594 1.00 73.99  ? 216  VAL A CA  1 
ATOM   85   C C   . VAL A 1 94   ? 161.828 134.396 190.000 1.00 77.44  ? 216  VAL A C   1 
ATOM   86   O O   . VAL A 1 94   ? 161.660 135.600 190.251 1.00 84.93  ? 216  VAL A O   1 
ATOM   87   C CB  . VAL A 1 94   ? 161.072 133.385 187.756 1.00 70.57  ? 216  VAL A CB  1 
ATOM   88   C CG1 . VAL A 1 94   ? 159.773 134.106 187.983 1.00 70.24  ? 216  VAL A CG1 1 
ATOM   89   C CG2 . VAL A 1 94   ? 161.406 133.500 186.287 1.00 72.21  ? 216  VAL A CG2 1 
ATOM   90   N N   . THR A 1 95   ? 161.780 133.454 190.959 1.00 74.92  ? 217  THR A N   1 
ATOM   91   C CA  . THR A 1 95   ? 161.432 133.771 192.345 1.00 73.28  ? 217  THR A CA  1 
ATOM   92   C C   . THR A 1 95   ? 162.546 134.559 193.047 1.00 77.42  ? 217  THR A C   1 
ATOM   93   O O   . THR A 1 95   ? 162.267 135.520 193.779 1.00 82.97  ? 217  THR A O   1 
ATOM   94   C CB  . THR A 1 95   ? 161.114 132.468 193.089 1.00 73.99  ? 217  THR A CB  1 
ATOM   95   O OG1 . THR A 1 95   ? 160.093 131.763 192.377 1.00 78.19  ? 217  THR A OG1 1 
ATOM   96   C CG2 . THR A 1 95   ? 160.594 132.723 194.497 1.00 75.92  ? 217  THR A CG2 1 
ATOM   97   N N   . ARG A 1 96   ? 163.812 134.233 192.745 1.00 74.90  ? 218  ARG A N   1 
ATOM   98   C CA  . ARG A 1 96   ? 164.953 134.946 193.316 1.00 75.78  ? 218  ARG A CA  1 
ATOM   99   C C   . ARG A 1 96   ? 165.094 136.354 192.737 1.00 78.69  ? 218  ARG A C   1 
ATOM   100  O O   . ARG A 1 96   ? 165.357 137.313 193.482 1.00 84.53  ? 218  ARG A O   1 
ATOM   101  C CB  . ARG A 1 96   ? 166.217 134.113 193.086 1.00 78.69  ? 218  ARG A CB  1 
ATOM   102  C CG  . ARG A 1 96   ? 167.543 134.779 193.393 1.00 81.12  ? 218  ARG A CG  1 
ATOM   103  C CD  . ARG A 1 96   ? 168.692 133.878 192.972 1.00 83.52  ? 218  ARG A CD  1 
ATOM   104  N NE  . ARG A 1 96   ? 168.435 133.231 191.690 1.00 86.01  ? 218  ARG A NE  1 
ATOM   105  C CZ  . ARG A 1 96   ? 169.352 132.592 190.976 1.00 90.08  ? 218  ARG A CZ  1 
ATOM   106  N NH1 . ARG A 1 96   ? 170.601 132.486 191.395 1.00 91.57  ? 218  ARG A NH1 1 
ATOM   107  N NH2 . ARG A 1 96   ? 169.005 132.043 189.816 1.00 89.15  ? 218  ARG A NH2 1 
ATOM   108  N N   . ASP A 1 97   ? 164.842 136.509 191.426 1.00 76.74  ? 219  ASP A N   1 
ATOM   109  C CA  . ASP A 1 97   ? 164.843 137.828 190.797 1.00 79.03  ? 219  ASP A CA  1 
ATOM   110  C C   . ASP A 1 97   ? 163.651 138.672 191.230 1.00 77.97  ? 219  ASP A C   1 
ATOM   111  O O   . ASP A 1 97   ? 163.778 139.896 191.340 1.00 81.80  ? 219  ASP A O   1 
ATOM   112  C CB  . ASP A 1 97   ? 164.852 137.681 189.276 1.00 83.18  ? 219  ASP A CB  1 
ATOM   113  C CG  . ASP A 1 97   ? 166.213 137.296 188.733 1.00 91.95  ? 219  ASP A CG  1 
ATOM   114  O OD1 . ASP A 1 97   ? 167.170 137.186 189.527 1.00 93.36  ? 219  ASP A OD1 1 
ATOM   115  O OD2 . ASP A 1 97   ? 166.326 137.101 187.505 1.00 91.03  ? 219  ASP A OD2 1 
ATOM   116  N N   . CYS A 1 98   ? 162.518 138.029 191.543 1.00 75.62  ? 220  CYS A N   1 
ATOM   117  C CA  . CYS A 1 98   ? 161.342 138.734 192.043 1.00 75.30  ? 220  CYS A CA  1 
ATOM   118  C C   . CYS A 1 98   ? 161.553 139.252 193.460 1.00 78.25  ? 220  CYS A C   1 
ATOM   119  O O   . CYS A 1 98   ? 161.201 140.400 193.752 1.00 83.22  ? 220  CYS A O   1 
ATOM   120  C CB  . CYS A 1 98   ? 160.130 137.806 191.996 1.00 79.20  ? 220  CYS A CB  1 
ATOM   121  S SG  . CYS A 1 98   ? 158.522 138.630 192.057 1.00 89.78  ? 220  CYS A SG  1 
ATOM   122  N N   . VAL A 1 99   ? 162.150 138.431 194.335 1.00 76.42  ? 221  VAL A N   1 
ATOM   123  C CA  . VAL A 1 99   ? 162.445 138.823 195.716 1.00 75.06  ? 221  VAL A CA  1 
ATOM   124  C C   . VAL A 1 99   ? 163.529 139.906 195.771 1.00 77.00  ? 221  VAL A C   1 
ATOM   125  O O   . VAL A 1 99   ? 163.395 140.881 196.529 1.00 81.34  ? 221  VAL A O   1 
ATOM   126  C CB  . VAL A 1 99   ? 162.791 137.552 196.526 1.00 75.75  ? 221  VAL A CB  1 
ATOM   127  C CG1 . VAL A 1 99   ? 163.482 137.842 197.854 1.00 77.63  ? 221  VAL A CG1 1 
ATOM   128  C CG2 . VAL A 1 99   ? 161.520 136.778 196.812 1.00 74.28  ? 221  VAL A CG2 1 
ATOM   129  N N   . GLN A 1 100  ? 164.541 139.824 194.891 1.00 75.62  ? 222  GLN A N   1 
ATOM   130  C CA  . GLN A 1 100  ? 165.565 140.866 194.791 1.00 78.52  ? 222  GLN A CA  1 
ATOM   131  C C   . GLN A 1 100  ? 165.013 142.169 194.196 1.00 79.89  ? 222  GLN A C   1 
ATOM   132  O O   . GLN A 1 100  ? 165.420 143.263 194.619 1.00 81.22  ? 222  GLN A O   1 
ATOM   133  C CB  . GLN A 1 100  ? 166.739 140.328 193.965 1.00 78.81  ? 222  GLN A CB  1 
ATOM   134  C CG  . GLN A 1 100  ? 167.945 141.239 193.850 1.00 84.14  ? 222  GLN A CG  1 
ATOM   135  C CD  . GLN A 1 100  ? 168.566 141.517 195.203 1.00 88.74  ? 222  GLN A CD  1 
ATOM   136  O OE1 . GLN A 1 100  ? 168.409 142.603 195.762 1.00 90.40  ? 222  GLN A OE1 1 
ATOM   137  N NE2 . GLN A 1 100  ? 169.269 140.530 195.744 1.00 88.42  ? 222  GLN A NE2 1 
ATOM   138  N N   . ARG A 1 101  ? 164.030 142.063 193.290 1.00 78.39  ? 223  ARG A N   1 
ATOM   139  C CA  . ARG A 1 101  ? 163.315 143.229 192.777 1.00 76.36  ? 223  ARG A CA  1 
ATOM   140  C C   . ARG A 1 101  ? 162.431 143.884 193.832 1.00 79.71  ? 223  ARG A C   1 
ATOM   141  O O   . ARG A 1 101  ? 162.258 145.107 193.810 1.00 84.77  ? 223  ARG A O   1 
ATOM   142  C CB  . ARG A 1 101  ? 162.474 142.816 191.571 1.00 73.24  ? 223  ARG A CB  1 
ATOM   143  C CG  . ARG A 1 101  ? 162.140 143.925 190.602 1.00 73.53  ? 223  ARG A CG  1 
ATOM   144  C CD  . ARG A 1 101  ? 161.852 143.348 189.230 1.00 76.47  ? 223  ARG A CD  1 
ATOM   145  N NE  . ARG A 1 101  ? 161.071 142.120 189.310 1.00 78.24  ? 223  ARG A NE  1 
ATOM   146  C CZ  . ARG A 1 101  ? 161.051 141.185 188.372 1.00 77.78  ? 223  ARG A CZ  1 
ATOM   147  N NH1 . ARG A 1 101  ? 161.746 141.314 187.255 1.00 74.00  ? 223  ARG A NH1 1 
ATOM   148  N NH2 . ARG A 1 101  ? 160.318 140.093 188.561 1.00 77.17  ? 223  ARG A NH2 1 
ATOM   149  N N   . CYS A 1 102  ? 161.862 143.102 194.752 1.00 77.57  ? 224  CYS A N   1 
ATOM   150  C CA  . CYS A 1 102  ? 161.135 143.711 195.866 1.00 77.30  ? 224  CYS A CA  1 
ATOM   151  C C   . CYS A 1 102  ? 162.068 144.305 196.909 1.00 80.87  ? 224  CYS A C   1 
ATOM   152  O O   . CYS A 1 102  ? 161.652 145.203 197.647 1.00 82.64  ? 224  CYS A O   1 
ATOM   153  C CB  . CYS A 1 102  ? 160.233 142.697 196.556 1.00 78.55  ? 224  CYS A CB  1 
ATOM   154  S SG  . CYS A 1 102  ? 158.973 142.026 195.512 1.00 84.21  ? 224  CYS A SG  1 
ATOM   155  N N   . ILE A 1 103  ? 163.294 143.782 197.013 1.00 82.81  ? 225  ILE A N   1 
ATOM   156  C CA  . ILE A 1 103  ? 164.302 144.358 197.904 1.00 82.25  ? 225  ILE A CA  1 
ATOM   157  C C   . ILE A 1 103  ? 164.755 145.724 197.398 1.00 83.55  ? 225  ILE A C   1 
ATOM   158  O O   . ILE A 1 103  ? 164.786 146.698 198.165 1.00 85.65  ? 225  ILE A O   1 
ATOM   159  C CB  . ILE A 1 103  ? 165.478 143.368 198.070 1.00 82.41  ? 225  ILE A CB  1 
ATOM   160  C CG1 . ILE A 1 103  ? 165.112 142.251 199.048 1.00 81.22  ? 225  ILE A CG1 1 
ATOM   161  C CG2 . ILE A 1 103  ? 166.784 144.041 198.525 1.00 85.53  ? 225  ILE A CG2 1 
ATOM   162  C CD1 . ILE A 1 103  ? 164.824 142.731 200.445 1.00 84.12  ? 225  ILE A CD1 1 
ATOM   163  N N   . VAL A 1 104  ? 165.055 145.834 196.095 1.00 82.49  ? 226  VAL A N   1 
ATOM   164  C CA  . VAL A 1 104  ? 165.680 147.052 195.572 1.00 84.67  ? 226  VAL A CA  1 
ATOM   165  C C   . VAL A 1 104  ? 164.651 148.183 195.406 1.00 84.76  ? 226  VAL A C   1 
ATOM   166  O O   . VAL A 1 104  ? 164.976 149.365 195.576 1.00 87.15  ? 226  VAL A O   1 
ATOM   167  C CB  . VAL A 1 104  ? 166.471 146.735 194.274 1.00 86.75  ? 226  VAL A CB  1 
ATOM   168  C CG1 . VAL A 1 104  ? 165.601 146.279 193.098 1.00 82.40  ? 226  VAL A CG1 1 
ATOM   169  C CG2 . VAL A 1 104  ? 167.422 147.864 193.866 1.00 92.13  ? 226  VAL A CG2 1 
ATOM   170  N N   . GLU A 1 105  ? 163.386 147.847 195.156 1.00 83.73  ? 227  GLU A N   1 
ATOM   171  C CA  . GLU A 1 105  ? 162.355 148.842 194.863 1.00 83.53  ? 227  GLU A CA  1 
ATOM   172  C C   . GLU A 1 105  ? 161.435 149.115 196.046 1.00 84.88  ? 227  GLU A C   1 
ATOM   173  O O   . GLU A 1 105  ? 160.260 149.434 195.857 1.00 85.95  ? 227  GLU A O   1 
ATOM   174  C CB  . GLU A 1 105  ? 161.546 148.407 193.650 1.00 81.83  ? 227  GLU A CB  1 
ATOM   175  C CG  . GLU A 1 105  ? 162.345 148.404 192.367 1.00 87.19  ? 227  GLU A CG  1 
ATOM   176  C CD  . GLU A 1 105  ? 161.533 147.951 191.179 1.00 92.54  ? 227  GLU A CD  1 
ATOM   177  O OE1 . GLU A 1 105  ? 160.382 147.518 191.381 1.00 90.26  ? 227  GLU A OE1 1 
ATOM   178  O OE2 . GLU A 1 105  ? 162.041 148.037 190.041 1.00 94.34  ? 227  GLU A OE2 1 
ATOM   179  N N   . GLU A 1 106  ? 161.938 149.014 197.276 1.00 85.10  ? 228  GLU A N   1 
ATOM   180  C CA  . GLU A 1 106  ? 161.082 149.155 198.451 1.00 86.25  ? 228  GLU A CA  1 
ATOM   181  C C   . GLU A 1 106  ? 160.799 150.609 198.813 1.00 88.47  ? 228  GLU A C   1 
ATOM   182  O O   . GLU A 1 106  ? 159.890 150.876 199.607 1.00 88.76  ? 228  GLU A O   1 
ATOM   183  C CB  . GLU A 1 106  ? 161.713 148.428 199.636 1.00 89.06  ? 228  GLU A CB  1 
ATOM   184  C CG  . GLU A 1 106  ? 163.027 149.025 200.100 1.00 95.60  ? 228  GLU A CG  1 
ATOM   185  C CD  . GLU A 1 106  ? 163.658 148.241 201.231 1.00 102.35 ? 228  GLU A CD  1 
ATOM   186  O OE1 . GLU A 1 106  ? 163.076 147.214 201.642 1.00 99.47  ? 228  GLU A OE1 1 
ATOM   187  O OE2 . GLU A 1 106  ? 164.743 148.642 201.697 1.00 107.91 ? 228  GLU A OE2 1 
ATOM   188  N N   . ASP A 1 107  ? 161.554 151.554 198.260 1.00 90.57  ? 229  ASP A N   1 
ATOM   189  C CA  . ASP A 1 107  ? 161.363 152.974 198.524 1.00 90.68  ? 229  ASP A CA  1 
ATOM   190  C C   . ASP A 1 107  ? 161.072 153.793 197.269 1.00 87.03  ? 229  ASP A C   1 
ATOM   191  O O   . ASP A 1 107  ? 161.183 155.022 197.299 1.00 88.91  ? 229  ASP A O   1 
ATOM   192  C CB  . ASP A 1 107  ? 162.568 153.525 199.311 1.00 91.67  ? 229  ASP A CB  1 
ATOM   193  C CG  . ASP A 1 107  ? 163.924 153.421 198.565 1.00 97.55  ? 229  ASP A CG  1 
ATOM   194  O OD1 . ASP A 1 107  ? 164.049 152.886 197.438 1.00 96.84  ? 229  ASP A OD1 1 
ATOM   195  O OD2 . ASP A 1 107  ? 164.913 153.907 199.148 1.00 100.73 ? 229  ASP A OD2 1 
ATOM   196  N N   . LEU A 1 108  ? 160.714 153.133 196.172 1.00 81.41  ? 230  LEU A N   1 
ATOM   197  C CA  . LEU A 1 108  ? 160.625 153.793 194.878 1.00 77.97  ? 230  LEU A CA  1 
ATOM   198  C C   . LEU A 1 108  ? 159.233 154.357 194.618 1.00 77.08  ? 230  LEU A C   1 
ATOM   199  O O   . LEU A 1 108  ? 159.095 155.356 193.903 1.00 78.32  ? 230  LEU A O   1 
ATOM   200  C CB  . LEU A 1 108  ? 161.031 152.792 193.799 1.00 77.20  ? 230  LEU A CB  1 
ATOM   201  C CG  . LEU A 1 108  ? 161.152 153.169 192.333 1.00 76.36  ? 230  LEU A CG  1 
ATOM   202  C CD1 . LEU A 1 108  ? 162.430 153.948 192.101 1.00 73.69  ? 230  LEU A CD1 1 
ATOM   203  C CD2 . LEU A 1 108  ? 161.135 151.913 191.493 1.00 76.48  ? 230  LEU A CD2 1 
ATOM   204  N N   . PHE A 1 109  ? 158.209 153.757 195.212 1.00 76.15  ? 231  PHE A N   1 
ATOM   205  C CA  . PHE A 1 109  ? 156.815 154.083 194.953 1.00 72.41  ? 231  PHE A CA  1 
ATOM   206  C C   . PHE A 1 109  ? 156.224 154.703 196.211 1.00 74.89  ? 231  PHE A C   1 
ATOM   207  O O   . PHE A 1 109  ? 156.473 154.201 197.312 1.00 79.20  ? 231  PHE A O   1 
ATOM   208  C CB  . PHE A 1 109  ? 156.044 152.809 194.594 1.00 68.69  ? 231  PHE A CB  1 
ATOM   209  C CG  . PHE A 1 109  ? 156.501 152.146 193.322 1.00 66.36  ? 231  PHE A CG  1 
ATOM   210  C CD1 . PHE A 1 109  ? 156.066 152.608 192.089 1.00 59.05  ? 231  PHE A CD1 1 
ATOM   211  C CD2 . PHE A 1 109  ? 157.374 151.056 193.369 1.00 72.03  ? 231  PHE A CD2 1 
ATOM   212  C CE1 . PHE A 1 109  ? 156.500 152.012 190.905 1.00 57.72  ? 231  PHE A CE1 1 
ATOM   213  C CE2 . PHE A 1 109  ? 157.810 150.441 192.190 1.00 71.46  ? 231  PHE A CE2 1 
ATOM   214  C CZ  . PHE A 1 109  ? 157.363 150.924 190.960 1.00 65.46  ? 231  PHE A CZ  1 
ATOM   215  N N   . LEU A 1 110  ? 155.449 155.785 196.077 1.00 75.96  ? 232  LEU A N   1 
ATOM   216  C CA  . LEU A 1 110  ? 154.671 156.231 197.226 1.00 81.74  ? 232  LEU A CA  1 
ATOM   217  C C   . LEU A 1 110  ? 153.325 155.523 197.168 1.00 85.79  ? 232  LEU A C   1 
ATOM   218  O O   . LEU A 1 110  ? 152.654 155.526 196.131 1.00 84.96  ? 232  LEU A O   1 
ATOM   219  C CB  . LEU A 1 110  ? 154.464 157.751 197.328 1.00 82.12  ? 232  LEU A CB  1 
ATOM   220  C CG  . LEU A 1 110  ? 153.587 158.748 196.554 1.00 82.99  ? 232  LEU A CG  1 
ATOM   221  C CD1 . LEU A 1 110  ? 153.526 160.036 197.359 1.00 80.16  ? 232  LEU A CD1 1 
ATOM   222  C CD2 . LEU A 1 110  ? 154.058 159.084 195.188 1.00 84.63  ? 232  LEU A CD2 1 
ATOM   223  N N   . ASP A 1 111  ? 152.951 154.891 198.275 1.00 88.57  ? 233  ASP A N   1 
ATOM   224  C CA  . ASP A 1 111  ? 151.748 154.084 198.343 1.00 89.68  ? 233  ASP A CA  1 
ATOM   225  C C   . ASP A 1 111  ? 150.550 155.019 198.521 1.00 93.23  ? 233  ASP A C   1 
ATOM   226  O O   . ASP A 1 111  ? 150.718 156.198 198.854 1.00 91.82  ? 233  ASP A O   1 
ATOM   227  C CB  . ASP A 1 111  ? 151.878 153.091 199.492 1.00 91.84  ? 233  ASP A CB  1 
ATOM   228  C CG  . ASP A 1 111  ? 151.104 151.818 199.260 1.00 98.36  ? 233  ASP A CG  1 
ATOM   229  O OD1 . ASP A 1 111  ? 150.445 151.706 198.222 1.00 98.85  ? 233  ASP A OD1 1 
ATOM   230  O OD2 . ASP A 1 111  ? 151.177 150.905 200.108 1.00 102.04 ? 233  ASP A OD2 1 
ATOM   231  N N   . GLU A 1 112  ? 149.337 154.533 198.243 1.00 94.03  ? 234  GLU A N   1 
ATOM   232  C CA  . GLU A 1 112  ? 148.131 155.409 198.238 1.00 92.89  ? 234  GLU A CA  1 
ATOM   233  C C   . GLU A 1 112  ? 147.744 155.886 199.636 1.00 92.81  ? 234  GLU A C   1 
ATOM   234  O O   . GLU A 1 112  ? 147.078 156.922 199.725 1.00 96.71  ? 234  GLU A O   1 
ATOM   235  C CB  . GLU A 1 112  ? 146.966 154.668 197.589 1.00 93.52  ? 234  GLU A CB  1 
ATOM   236  C CG  . GLU A 1 112  ? 146.964 153.185 197.900 1.00 96.50  ? 234  GLU A CG  1 
ATOM   237  C CD  . GLU A 1 112  ? 145.871 152.384 197.218 1.00 101.94 ? 234  GLU A CD  1 
ATOM   238  O OE1 . GLU A 1 112  ? 144.994 153.001 196.584 1.00 101.22 ? 234  GLU A OE1 1 
ATOM   239  O OE2 . GLU A 1 112  ? 145.903 151.141 197.319 1.00 104.35 ? 234  GLU A OE2 1 
ATOM   240  N N   . PHE A 1 113  ? 148.107 155.140 200.674 1.00 91.15  ? 235  PHE A N   1 
ATOM   241  C CA  . PHE A 1 113  ? 147.770 155.536 202.033 1.00 89.27  ? 235  PHE A CA  1 
ATOM   242  C C   . PHE A 1 113  ? 148.900 156.257 202.754 1.00 89.11  ? 235  PHE A C   1 
ATOM   243  O O   . PHE A 1 113  ? 148.692 156.707 203.887 1.00 89.11  ? 235  PHE A O   1 
ATOM   244  C CB  . PHE A 1 113  ? 147.337 154.314 202.849 1.00 89.24  ? 235  PHE A CB  1 
ATOM   245  C CG  . PHE A 1 113  ? 146.231 153.528 202.215 1.00 92.25  ? 235  PHE A CG  1 
ATOM   246  C CD1 . PHE A 1 113  ? 144.929 154.031 202.211 1.00 92.74  ? 235  PHE A CD1 1 
ATOM   247  C CD2 . PHE A 1 113  ? 146.494 152.305 201.599 1.00 93.06  ? 235  PHE A CD2 1 
ATOM   248  C CE1 . PHE A 1 113  ? 143.891 153.315 201.621 1.00 90.65  ? 235  PHE A CE1 1 
ATOM   249  C CE2 . PHE A 1 113  ? 145.465 151.576 200.999 1.00 94.68  ? 235  PHE A CE2 1 
ATOM   250  C CZ  . PHE A 1 113  ? 144.163 152.088 201.012 1.00 91.71  ? 235  PHE A CZ  1 
ATOM   251  N N   . GLY A 1 114  ? 150.067 156.406 202.126 1.00 89.77  ? 236  GLY A N   1 
ATOM   252  C CA  . GLY A 1 114  ? 151.209 157.040 202.757 1.00 89.68  ? 236  GLY A CA  1 
ATOM   253  C C   . GLY A 1 114  ? 151.816 156.185 203.849 1.00 92.90  ? 236  GLY A C   1 
ATOM   254  O O   . GLY A 1 114  ? 151.746 156.538 205.029 1.00 92.73  ? 236  GLY A O   1 
ATOM   255  N N   . ILE A 1 115  ? 152.396 155.050 203.464 1.00 94.18  ? 237  ILE A N   1 
ATOM   256  C CA  . ILE A 1 115  ? 152.807 154.044 204.439 1.00 96.14  ? 237  ILE A CA  1 
ATOM   257  C C   . ILE A 1 115  ? 154.126 154.429 205.095 1.00 100.84 ? 237  ILE A C   1 
ATOM   258  O O   . ILE A 1 115  ? 154.172 154.635 206.316 1.00 103.01 ? 237  ILE A O   1 
ATOM   259  C CB  . ILE A 1 115  ? 152.896 152.662 203.772 1.00 93.23  ? 237  ILE A CB  1 
ATOM   260  C CG1 . ILE A 1 115  ? 151.552 152.276 203.153 1.00 88.29  ? 237  ILE A CG1 1 
ATOM   261  C CG2 . ILE A 1 115  ? 153.344 151.629 204.770 1.00 95.17  ? 237  ILE A CG2 1 
ATOM   262  C CD1 . ILE A 1 115  ? 150.429 152.100 204.129 1.00 86.96  ? 237  ILE A CD1 1 
ATOM   263  N N   . GLN A 1 116  ? 155.191 154.522 204.281 1.00 99.26  ? 238  GLN A N   1 
ATOM   264  C CA  . GLN A 1 116  ? 156.556 154.974 204.607 1.00 104.05 ? 238  GLN A CA  1 
ATOM   265  C C   . GLN A 1 116  ? 157.195 154.119 205.711 1.00 107.63 ? 238  GLN A C   1 
ATOM   266  O O   . GLN A 1 116  ? 157.509 154.586 206.809 1.00 109.22 ? 238  GLN A O   1 
ATOM   267  C CB  . GLN A 1 116  ? 156.577 156.469 204.963 1.00 107.19 ? 238  GLN A CB  1 
ATOM   268  C CG  . GLN A 1 116  ? 157.894 157.168 204.675 1.00 109.90 ? 238  GLN A CG  1 
ATOM   269  C CD  . GLN A 1 116  ? 157.847 158.646 204.998 1.00 113.41 ? 238  GLN A CD  1 
ATOM   270  O OE1 . GLN A 1 116  ? 156.779 159.201 205.253 1.00 112.01 ? 238  GLN A OE1 1 
ATOM   271  N NE2 . GLN A 1 116  ? 159.006 159.293 204.987 1.00 115.27 ? 238  GLN A NE2 1 
ATOM   272  N N   . CYS A 1 117  ? 157.366 152.842 205.390 1.00 107.15 ? 239  CYS A N   1 
ATOM   273  C CA  . CYS A 1 117  ? 158.047 151.922 206.289 1.00 110.09 ? 239  CYS A CA  1 
ATOM   274  C C   . CYS A 1 117  ? 159.552 152.147 206.261 1.00 115.30 ? 239  CYS A C   1 
ATOM   275  O O   . CYS A 1 117  ? 160.100 152.786 205.361 1.00 115.17 ? 239  CYS A O   1 
ATOM   276  C CB  . CYS A 1 117  ? 157.754 150.466 205.927 1.00 109.83 ? 239  CYS A CB  1 
ATOM   277  S SG  . CYS A 1 117  ? 156.155 149.829 206.438 1.00 113.59 ? 239  CYS A SG  1 
ATOM   278  N N   . GLU A 1 118  ? 160.220 151.591 207.265 1.00 117.85 ? 240  GLU A N   1 
ATOM   279  C CA  . GLU A 1 118  ? 161.671 151.563 207.285 1.00 118.81 ? 240  GLU A CA  1 
ATOM   280  C C   . GLU A 1 118  ? 162.183 150.376 206.473 1.00 118.62 ? 240  GLU A C   1 
ATOM   281  O O   . GLU A 1 118  ? 161.411 149.584 205.926 1.00 118.82 ? 240  GLU A O   1 
ATOM   282  C CB  . GLU A 1 118  ? 162.190 151.489 208.722 1.00 119.89 ? 240  GLU A CB  1 
ATOM   283  C CG  . GLU A 1 118  ? 161.892 152.728 209.559 1.00 123.42 ? 240  GLU A CG  1 
ATOM   284  C CD  . GLU A 1 118  ? 162.666 153.956 209.108 1.00 125.47 ? 240  GLU A CD  1 
ATOM   285  O OE1 . GLU A 1 118  ? 163.818 153.810 208.647 1.00 121.64 ? 240  GLU A OE1 1 
ATOM   286  O OE2 . GLU A 1 118  ? 162.118 155.073 209.217 1.00 126.34 ? 240  GLU A OE2 1 
ATOM   287  N N   . LYS A 1 119  ? 163.510 150.257 206.406 1.00 119.27 ? 241  LYS A N   1 
ATOM   288  C CA  . LYS A 1 119  ? 164.116 149.219 205.580 1.00 116.81 ? 241  LYS A CA  1 
ATOM   289  C C   . LYS A 1 119  ? 164.061 147.843 206.230 1.00 115.41 ? 241  LYS A C   1 
ATOM   290  O O   . LYS A 1 119  ? 164.196 146.835 205.529 1.00 112.62 ? 241  LYS A O   1 
ATOM   291  C CB  . LYS A 1 119  ? 165.558 149.596 205.247 1.00 116.83 ? 241  LYS A CB  1 
ATOM   292  C CG  . LYS A 1 119  ? 165.660 150.722 204.230 1.00 119.02 ? 241  LYS A CG  1 
ATOM   293  C CD  . LYS A 1 119  ? 167.085 150.939 203.759 1.00 122.05 ? 241  LYS A CD  1 
ATOM   294  C CE  . LYS A 1 119  ? 167.145 152.029 202.700 1.00 125.57 ? 241  LYS A CE  1 
ATOM   295  N NZ  . LYS A 1 119  ? 168.522 152.226 202.173 1.00 133.17 ? 241  LYS A NZ  1 
ATOM   296  N N   . ALA A 1 120  ? 163.866 147.773 207.548 1.00 117.57 ? 242  ALA A N   1 
ATOM   297  C CA  . ALA A 1 120  ? 163.671 146.507 208.252 1.00 116.98 ? 242  ALA A CA  1 
ATOM   298  C C   . ALA A 1 120  ? 162.508 146.671 209.234 1.00 120.53 ? 242  ALA A C   1 
ATOM   299  O O   . ALA A 1 120  ? 162.703 147.006 210.404 1.00 123.39 ? 242  ALA A O   1 
ATOM   300  C CB  . ALA A 1 120  ? 164.950 146.065 208.961 1.00 114.73 ? 242  ALA A CB  1 
ATOM   301  N N   . ASP A 1 121  ? 161.292 146.427 208.751 1.00 120.07 ? 243  ASP A N   1 
ATOM   302  C CA  . ASP A 1 121  ? 160.101 146.498 209.590 1.00 121.07 ? 243  ASP A CA  1 
ATOM   303  C C   . ASP A 1 121  ? 159.336 145.184 209.644 1.00 120.03 ? 243  ASP A C   1 
ATOM   304  O O   . ASP A 1 121  ? 158.911 144.782 210.736 1.00 119.95 ? 243  ASP A O   1 
ATOM   305  C CB  . ASP A 1 121  ? 159.166 147.607 209.100 1.00 118.68 ? 243  ASP A CB  1 
ATOM   306  C CG  . ASP A 1 121  ? 158.044 147.894 210.079 1.00 117.72 ? 243  ASP A CG  1 
ATOM   307  O OD1 . ASP A 1 121  ? 158.334 148.071 211.280 1.00 117.52 ? 243  ASP A OD1 1 
ATOM   308  O OD2 . ASP A 1 121  ? 156.871 147.941 209.654 1.00 115.55 ? 243  ASP A OD2 1 
ATOM   309  N N   . ASN A 1 122  ? 159.152 144.549 208.473 1.00 116.53 ? 244  ASN A N   1 
ATOM   310  C CA  . ASN A 1 122  ? 158.505 143.240 208.253 1.00 113.35 ? 244  ASN A CA  1 
ATOM   311  C C   . ASN A 1 122  ? 157.060 143.201 208.755 1.00 111.94 ? 244  ASN A C   1 
ATOM   312  O O   . ASN A 1 122  ? 156.581 142.194 209.280 1.00 111.13 ? 244  ASN A O   1 
ATOM   313  C CB  . ASN A 1 122  ? 159.329 142.092 208.854 1.00 116.83 ? 244  ASN A CB  1 
ATOM   314  C CG  . ASN A 1 122  ? 160.746 142.056 208.323 1.00 120.05 ? 244  ASN A CG  1 
ATOM   315  O OD1 . ASN A 1 122  ? 161.089 142.777 207.386 1.00 118.67 ? 244  ASN A OD1 1 
ATOM   316  N ND2 . ASN A 1 122  ? 161.580 141.212 208.921 1.00 122.73 ? 244  ASN A ND2 1 
ATOM   317  N N   . GLY A 1 123  ? 156.356 144.323 208.584 1.00 110.03 ? 245  GLY A N   1 
ATOM   318  C CA  . GLY A 1 123  ? 154.948 144.393 208.897 1.00 105.92 ? 245  GLY A CA  1 
ATOM   319  C C   . GLY A 1 123  ? 154.131 144.390 207.617 1.00 101.00 ? 245  GLY A C   1 
ATOM   320  O O   . GLY A 1 123  ? 154.658 144.609 206.528 1.00 98.81  ? 245  GLY A O   1 
ATOM   321  N N   . GLU A 1 124  ? 152.833 144.099 207.734 1.00 98.57  ? 246  GLU A N   1 
ATOM   322  C CA  . GLU A 1 124  ? 151.975 143.947 206.528 1.00 96.93  ? 246  GLU A CA  1 
ATOM   323  C C   . GLU A 1 124  ? 151.820 145.250 205.744 1.00 94.92  ? 246  GLU A C   1 
ATOM   324  O O   . GLU A 1 124  ? 151.606 145.162 204.530 1.00 93.82  ? 246  GLU A O   1 
ATOM   325  C CB  . GLU A 1 124  ? 150.594 143.445 206.935 1.00 100.72 ? 246  GLU A CB  1 
ATOM   326  C CG  . GLU A 1 124  ? 150.619 142.075 207.579 1.00 104.61 ? 246  GLU A CG  1 
ATOM   327  C CD  . GLU A 1 124  ? 149.298 141.654 208.197 1.00 110.95 ? 246  GLU A CD  1 
ATOM   328  O OE1 . GLU A 1 124  ? 149.122 140.447 208.449 1.00 112.81 ? 246  GLU A OE1 1 
ATOM   329  O OE2 . GLU A 1 124  ? 148.451 142.539 208.433 1.00 112.38 ? 246  GLU A OE2 1 
ATOM   330  N N   . LYS A 1 125  ? 151.899 146.404 206.400 1.00 95.38  ? 247  LYS A N   1 
ATOM   331  C CA  . LYS A 1 125  ? 151.651 147.659 205.705 1.00 93.28  ? 247  LYS A CA  1 
ATOM   332  C C   . LYS A 1 125  ? 152.654 147.942 204.597 1.00 92.96  ? 247  LYS A C   1 
ATOM   333  O O   . LYS A 1 125  ? 152.299 148.620 203.627 1.00 92.83  ? 247  LYS A O   1 
ATOM   334  C CB  . LYS A 1 125  ? 151.669 148.812 206.710 1.00 92.43  ? 247  LYS A CB  1 
ATOM   335  C CG  . LYS A 1 125  ? 152.762 148.681 207.758 1.00 95.46  ? 247  LYS A CG  1 
ATOM   336  C CD  . LYS A 1 125  ? 152.581 149.673 208.891 1.00 94.55  ? 247  LYS A CD  1 
ATOM   337  C CE  . LYS A 1 125  ? 153.120 151.039 208.515 1.00 97.04  ? 247  LYS A CE  1 
ATOM   338  N NZ  . LYS A 1 125  ? 153.113 151.966 209.679 1.00 93.66  ? 247  LYS A NZ  1 
ATOM   339  N N   . CYS A 1 126  ? 153.876 147.422 204.707 1.00 91.39  ? 248  CYS A N   1 
ATOM   340  C CA  . CYS A 1 126  ? 155.019 147.870 203.924 1.00 89.15  ? 248  CYS A CA  1 
ATOM   341  C C   . CYS A 1 126  ? 154.968 147.343 202.493 1.00 85.17  ? 248  CYS A C   1 
ATOM   342  O O   . CYS A 1 126  ? 154.160 146.480 202.148 1.00 87.65  ? 248  CYS A O   1 
ATOM   343  C CB  . CYS A 1 126  ? 156.318 147.434 204.595 1.00 89.71  ? 248  CYS A CB  1 
ATOM   344  S SG  . CYS A 1 126  ? 156.389 147.814 206.353 1.00 113.14 ? 248  CYS A SG  1 
ATOM   345  N N   . TYR A 1 127  ? 155.844 147.908 201.651 1.00 80.30  ? 249  TYR A N   1 
ATOM   346  C CA  . TYR A 1 127  ? 155.976 147.471 200.263 1.00 75.13  ? 249  TYR A CA  1 
ATOM   347  C C   . TYR A 1 127  ? 156.582 146.078 200.169 1.00 77.61  ? 249  TYR A C   1 
ATOM   348  O O   . TYR A 1 127  ? 156.229 145.316 199.259 1.00 79.89  ? 249  TYR A O   1 
ATOM   349  C CB  . TYR A 1 127  ? 156.835 148.470 199.474 1.00 75.51  ? 249  TYR A CB  1 
ATOM   350  C CG  . TYR A 1 127  ? 156.785 148.309 197.963 1.00 76.93  ? 249  TYR A CG  1 
ATOM   351  C CD1 . TYR A 1 127  ? 155.796 148.949 197.211 1.00 75.76  ? 249  TYR A CD1 1 
ATOM   352  C CD2 . TYR A 1 127  ? 157.746 147.540 197.283 1.00 78.27  ? 249  TYR A CD2 1 
ATOM   353  C CE1 . TYR A 1 127  ? 155.744 148.803 195.823 1.00 73.38  ? 249  TYR A CE1 1 
ATOM   354  C CE2 . TYR A 1 127  ? 157.698 147.381 195.907 1.00 75.77  ? 249  TYR A CE2 1 
ATOM   355  C CZ  . TYR A 1 127  ? 156.700 148.018 195.189 1.00 73.97  ? 249  TYR A CZ  1 
ATOM   356  O OH  . TYR A 1 127  ? 156.664 147.863 193.826 1.00 73.97  ? 249  TYR A OH  1 
ATOM   357  N N   . LYS A 1 128  ? 157.487 145.742 201.093 1.00 78.77  ? 250  LYS A N   1 
ATOM   358  C CA  . LYS A 1 128  ? 158.294 144.532 201.007 1.00 76.61  ? 250  LYS A CA  1 
ATOM   359  C C   . LYS A 1 128  ? 157.483 143.275 201.291 1.00 75.94  ? 250  LYS A C   1 
ATOM   360  O O   . LYS A 1 128  ? 157.632 142.278 200.580 1.00 79.85  ? 250  LYS A O   1 
ATOM   361  C CB  . LYS A 1 128  ? 159.474 144.633 201.973 1.00 83.06  ? 250  LYS A CB  1 
ATOM   362  C CG  . LYS A 1 128  ? 160.544 143.578 201.776 1.00 86.54  ? 250  LYS A CG  1 
ATOM   363  C CD  . LYS A 1 128  ? 161.853 143.982 202.442 1.00 93.26  ? 250  LYS A CD  1 
ATOM   364  C CE  . LYS A 1 128  ? 161.704 144.172 203.943 1.00 101.00 ? 250  LYS A CE  1 
ATOM   365  N NZ  . LYS A 1 128  ? 162.929 144.767 204.550 1.00 107.66 ? 250  LYS A NZ  1 
ATOM   366  N N   . THR A 1 129  ? 156.581 143.331 202.275 1.00 75.82  ? 251  THR A N   1 
ATOM   367  C CA  . THR A 1 129  ? 155.779 142.170 202.656 1.00 77.39  ? 251  THR A CA  1 
ATOM   368  C C   . THR A 1 129  ? 154.692 141.872 201.628 1.00 76.81  ? 251  THR A C   1 
ATOM   369  O O   . THR A 1 129  ? 154.482 140.707 201.268 1.00 81.71  ? 251  THR A O   1 
ATOM   370  C CB  . THR A 1 129  ? 155.168 142.402 204.037 1.00 83.45  ? 251  THR A CB  1 
ATOM   371  O OG1 . THR A 1 129  ? 156.198 142.810 204.943 1.00 89.39  ? 251  THR A OG1 1 
ATOM   372  C CG2 . THR A 1 129  ? 154.521 141.140 204.589 1.00 86.39  ? 251  THR A CG2 1 
ATOM   373  N N   . ARG A 1 130  ? 154.042 142.916 201.099 1.00 72.17  ? 252  ARG A N   1 
ATOM   374  C CA  . ARG A 1 130  ? 153.038 142.732 200.054 1.00 73.03  ? 252  ARG A CA  1 
ATOM   375  C C   . ARG A 1 130  ? 153.667 142.346 198.721 1.00 75.19  ? 252  ARG A C   1 
ATOM   376  O O   . ARG A 1 130  ? 153.077 141.565 197.962 1.00 80.55  ? 252  ARG A O   1 
ATOM   377  C CB  . ARG A 1 130  ? 152.213 144.004 199.886 1.00 74.93  ? 252  ARG A CB  1 
ATOM   378  C CG  . ARG A 1 130  ? 151.157 144.216 200.948 1.00 78.24  ? 252  ARG A CG  1 
ATOM   379  C CD  . ARG A 1 130  ? 151.021 145.690 201.262 1.00 81.24  ? 252  ARG A CD  1 
ATOM   380  N NE  . ARG A 1 130  ? 150.261 146.396 200.239 1.00 80.06  ? 252  ARG A NE  1 
ATOM   381  C CZ  . ARG A 1 130  ? 150.238 147.713 200.099 1.00 80.76  ? 252  ARG A CZ  1 
ATOM   382  N NH1 . ARG A 1 130  ? 150.944 148.503 200.889 1.00 86.23  ? 252  ARG A NH1 1 
ATOM   383  N NH2 . ARG A 1 130  ? 149.486 148.251 199.146 1.00 78.87  ? 252  ARG A NH2 1 
ATOM   384  N N   . CYS A 1 131  ? 154.875 142.841 198.442 1.00 72.94  ? 253  CYS A N   1 
ATOM   385  C CA  . CYS A 1 131  ? 155.534 142.493 197.189 1.00 70.46  ? 253  CYS A CA  1 
ATOM   386  C C   . CYS A 1 131  ? 156.109 141.078 197.261 1.00 73.52  ? 253  CYS A C   1 
ATOM   387  O O   . CYS A 1 131  ? 156.147 140.371 196.249 1.00 76.08  ? 253  CYS A O   1 
ATOM   388  C CB  . CYS A 1 131  ? 156.605 143.546 196.882 1.00 72.62  ? 253  CYS A CB  1 
ATOM   389  S SG  . CYS A 1 131  ? 157.541 143.443 195.321 1.00 80.80  ? 253  CYS A SG  1 
ATOM   390  N N   . THR A 1 132  ? 156.557 140.645 198.449 1.00 73.26  ? 254  THR A N   1 
ATOM   391  C CA  . THR A 1 132  ? 157.011 139.268 198.639 1.00 71.34  ? 254  THR A CA  1 
ATOM   392  C C   . THR A 1 132  ? 155.826 138.304 198.692 1.00 73.13  ? 254  THR A C   1 
ATOM   393  O O   . THR A 1 132  ? 155.959 137.126 198.339 1.00 78.92  ? 254  THR A O   1 
ATOM   394  C CB  . THR A 1 132  ? 157.870 139.197 199.910 1.00 71.38  ? 254  THR A CB  1 
ATOM   395  O OG1 . THR A 1 132  ? 158.762 140.316 199.929 1.00 75.69  ? 254  THR A OG1 1 
ATOM   396  C CG2 . THR A 1 132  ? 158.745 137.944 199.961 1.00 74.26  ? 254  THR A CG2 1 
ATOM   397  N N   . LYS A 1 133  ? 154.647 138.802 199.086 1.00 71.63  ? 255  LYS A N   1 
ATOM   398  C CA  . LYS A 1 133  ? 153.400 138.068 198.884 1.00 72.08  ? 255  LYS A CA  1 
ATOM   399  C C   . LYS A 1 133  ? 153.059 137.947 197.396 1.00 74.49  ? 255  LYS A C   1 
ATOM   400  O O   . LYS A 1 133  ? 152.458 136.951 196.975 1.00 79.32  ? 255  LYS A O   1 
ATOM   401  C CB  . LYS A 1 133  ? 152.282 138.770 199.666 1.00 75.16  ? 255  LYS A CB  1 
ATOM   402  C CG  . LYS A 1 133  ? 150.907 138.118 199.666 1.00 83.90  ? 255  LYS A CG  1 
ATOM   403  C CD  . LYS A 1 133  ? 149.936 138.906 200.523 1.00 85.51  ? 255  LYS A CD  1 
ATOM   404  C CE  . LYS A 1 133  ? 148.588 138.216 200.603 1.00 90.51  ? 255  LYS A CE  1 
ATOM   405  N NZ  . LYS A 1 133  ? 147.892 138.220 199.289 1.00 93.44  ? 255  LYS A NZ  1 
ATOM   406  N N   . GLY A 1 134  ? 153.457 138.936 196.588 1.00 74.42  ? 256  GLY A N   1 
ATOM   407  C CA  . GLY A 1 134  ? 153.335 138.815 195.142 1.00 72.45  ? 256  GLY A CA  1 
ATOM   408  C C   . GLY A 1 134  ? 154.237 137.776 194.500 1.00 72.75  ? 256  GLY A C   1 
ATOM   409  O O   . GLY A 1 134  ? 153.846 137.139 193.519 1.00 75.27  ? 256  GLY A O   1 
ATOM   410  N N   . CYS A 1 135  ? 155.444 137.590 195.027 1.00 75.02  ? 257  CYS A N   1 
ATOM   411  C CA  . CYS A 1 135  ? 156.378 136.623 194.465 1.00 73.87  ? 257  CYS A CA  1 
ATOM   412  C C   . CYS A 1 135  ? 156.252 135.241 195.086 1.00 73.82  ? 257  CYS A C   1 
ATOM   413  O O   . CYS A 1 135  ? 157.049 134.358 194.762 1.00 77.59  ? 257  CYS A O   1 
ATOM   414  C CB  . CYS A 1 135  ? 157.817 137.116 194.613 1.00 76.13  ? 257  CYS A CB  1 
ATOM   415  S SG  . CYS A 1 135  ? 158.075 138.792 194.032 1.00 87.17  ? 257  CYS A SG  1 
ATOM   416  N N   . ALA A 1 136  ? 155.292 135.034 195.982 1.00 73.37  ? 258  ALA A N   1 
ATOM   417  C CA  . ALA A 1 136  ? 155.013 133.704 196.494 1.00 71.89  ? 258  ALA A CA  1 
ATOM   418  C C   . ALA A 1 136  ? 153.804 133.060 195.840 1.00 76.90  ? 258  ALA A C   1 
ATOM   419  O O   . ALA A 1 136  ? 153.562 131.870 196.062 1.00 84.02  ? 258  ALA A O   1 
ATOM   420  C CB  . ALA A 1 136  ? 154.796 133.749 198.010 1.00 71.41  ? 258  ALA A CB  1 
ATOM   421  N N   . GLN A 1 137  ? 153.041 133.812 195.050 1.00 76.66  ? 259  GLN A N   1 
ATOM   422  C CA  . GLN A 1 137  ? 151.792 133.350 194.460 1.00 79.42  ? 259  GLN A CA  1 
ATOM   423  C C   . GLN A 1 137  ? 151.757 133.581 192.955 1.00 79.68  ? 259  GLN A C   1 
ATOM   424  O O   . GLN A 1 137  ? 150.691 133.779 192.371 1.00 85.87  ? 259  GLN A O   1 
ATOM   425  C CB  . GLN A 1 137  ? 150.594 134.033 195.117 1.00 79.34  ? 259  GLN A CB  1 
ATOM   426  C CG  . GLN A 1 137  ? 150.363 133.668 196.571 1.00 85.27  ? 259  GLN A CG  1 
ATOM   427  C CD  . GLN A 1 137  ? 149.181 134.393 197.161 1.00 97.09  ? 259  GLN A CD  1 
ATOM   428  O OE1 . GLN A 1 137  ? 148.562 135.225 196.503 1.00 97.52  ? 259  GLN A OE1 1 
ATOM   429  N NE2 . GLN A 1 137  ? 148.857 134.079 198.409 1.00 101.82 ? 259  GLN A NE2 1 
ATOM   430  N N   . TRP A 1 138  ? 152.915 133.555 192.300 1.00 74.39  ? 260  TRP A N   1 
ATOM   431  C CA  . TRP A 1 138  ? 152.933 133.688 190.849 1.00 73.24  ? 260  TRP A CA  1 
ATOM   432  C C   . TRP A 1 138  ? 152.792 132.348 190.138 1.00 79.27  ? 260  TRP A C   1 
ATOM   433  O O   . TRP A 1 138  ? 152.218 132.296 189.045 1.00 83.42  ? 260  TRP A O   1 
ATOM   434  C CB  . TRP A 1 138  ? 154.211 134.400 190.386 1.00 71.15  ? 260  TRP A CB  1 
ATOM   435  C CG  . TRP A 1 138  ? 155.481 133.638 190.629 1.00 74.30  ? 260  TRP A CG  1 
ATOM   436  C CD1 . TRP A 1 138  ? 156.214 133.616 191.771 1.00 76.83  ? 260  TRP A CD1 1 
ATOM   437  C CD2 . TRP A 1 138  ? 156.137 132.754 189.714 1.00 73.58  ? 260  TRP A CD2 1 
ATOM   438  N NE1 . TRP A 1 138  ? 157.297 132.786 191.628 1.00 77.23  ? 260  TRP A NE1 1 
ATOM   439  C CE2 . TRP A 1 138  ? 157.270 132.241 190.372 1.00 74.18  ? 260  TRP A CE2 1 
ATOM   440  C CE3 . TRP A 1 138  ? 155.872 132.344 188.402 1.00 71.87  ? 260  TRP A CE3 1 
ATOM   441  C CZ2 . TRP A 1 138  ? 158.142 131.340 189.763 1.00 75.73  ? 260  TRP A CZ2 1 
ATOM   442  C CZ3 . TRP A 1 138  ? 156.738 131.453 187.799 1.00 71.95  ? 260  TRP A CZ3 1 
ATOM   443  C CH2 . TRP A 1 138  ? 157.862 130.966 188.476 1.00 75.28  ? 260  TRP A CH2 1 
ATOM   444  N N   . TYR A 1 139  ? 153.308 131.269 190.725 1.00 80.21  ? 261  TYR A N   1 
ATOM   445  C CA  . TYR A 1 139  ? 153.198 129.945 190.137 1.00 80.68  ? 261  TYR A CA  1 
ATOM   446  C C   . TYR A 1 139  ? 151.921 129.243 190.553 1.00 86.23  ? 261  TYR A C   1 
ATOM   447  O O   . TYR A 1 139  ? 151.445 128.364 189.829 1.00 92.79  ? 261  TYR A O   1 
ATOM   448  C CB  . TYR A 1 139  ? 154.403 129.089 190.526 1.00 81.86  ? 261  TYR A CB  1 
ATOM   449  C CG  . TYR A 1 139  ? 154.586 127.880 189.647 1.00 85.07  ? 261  TYR A CG  1 
ATOM   450  C CD1 . TYR A 1 139  ? 154.745 128.023 188.265 1.00 87.12  ? 261  TYR A CD1 1 
ATOM   451  C CD2 . TYR A 1 139  ? 154.580 126.593 190.194 1.00 86.93  ? 261  TYR A CD2 1 
ATOM   452  C CE1 . TYR A 1 139  ? 154.908 126.910 187.443 1.00 92.58  ? 261  TYR A CE1 1 
ATOM   453  C CE2 . TYR A 1 139  ? 154.742 125.471 189.385 1.00 93.56  ? 261  TYR A CE2 1 
ATOM   454  C CZ  . TYR A 1 139  ? 154.905 125.643 188.015 1.00 97.00  ? 261  TYR A CZ  1 
ATOM   455  O OH  . TYR A 1 139  ? 155.065 124.539 187.210 1.00 101.19 ? 261  TYR A OH  1 
ATOM   456  N N   . ARG A 1 140  ? 151.355 129.625 191.697 1.00 83.71  ? 262  ARG A N   1 
ATOM   457  C CA  . ARG A 1 140  ? 150.020 129.178 192.067 1.00 86.76  ? 262  ARG A CA  1 
ATOM   458  C C   . ARG A 1 140  ? 148.962 129.830 191.183 1.00 88.59  ? 262  ARG A C   1 
ATOM   459  O O   . ARG A 1 140  ? 147.923 129.230 190.907 1.00 95.76  ? 262  ARG A O   1 
ATOM   460  C CB  . ARG A 1 140  ? 149.763 129.487 193.543 1.00 91.15  ? 262  ARG A CB  1 
ATOM   461  C CG  . ARG A 1 140  ? 148.571 128.773 194.157 1.00 92.90  ? 262  ARG A CG  1 
ATOM   462  C CD  . ARG A 1 140  ? 148.300 129.287 195.557 1.00 95.36  ? 262  ARG A CD  1 
ATOM   463  N NE  . ARG A 1 140  ? 147.951 130.704 195.537 1.00 98.34  ? 262  ARG A NE  1 
ATOM   464  C CZ  . ARG A 1 140  ? 146.726 131.173 195.347 1.00 97.92  ? 262  ARG A CZ  1 
ATOM   465  N NH1 . ARG A 1 140  ? 145.691 130.364 195.186 1.00 97.47  ? 262  ARG A NH1 1 
ATOM   466  N NH2 . ARG A 1 140  ? 146.533 132.488 195.320 1.00 96.09  ? 262  ARG A NH2 1 
ATOM   467  N N   . ALA A 1 141  ? 149.223 131.039 190.680 1.00 86.12  ? 263  ALA A N   1 
ATOM   468  C CA  . ALA A 1 141  ? 148.265 131.678 189.786 1.00 88.23  ? 263  ALA A CA  1 
ATOM   469  C C   . ALA A 1 141  ? 148.326 131.139 188.359 1.00 90.13  ? 263  ALA A C   1 
ATOM   470  O O   . ALA A 1 141  ? 147.440 131.452 187.561 1.00 93.66  ? 263  ALA A O   1 
ATOM   471  C CB  . ALA A 1 141  ? 148.476 133.191 189.779 1.00 82.19  ? 263  ALA A CB  1 
ATOM   472  N N   . LEU A 1 142  ? 149.418 130.493 187.972 1.00 86.11  ? 264  LEU A N   1 
ATOM   473  C CA  . LEU A 1 142  ? 149.434 130.022 186.569 1.00 86.49  ? 264  LEU A CA  1 
ATOM   474  C C   . LEU A 1 142  ? 148.746 128.659 186.548 1.00 92.03  ? 264  LEU A C   1 
ATOM   475  O O   . LEU A 1 142  ? 147.976 128.410 185.617 1.00 93.46  ? 264  LEU A O   1 
ATOM   476  C CB  . LEU A 1 142  ? 150.870 129.964 186.050 1.00 84.55  ? 264  LEU A CB  1 
ATOM   477  C CG  . LEU A 1 142  ? 151.446 131.293 185.573 1.00 80.68  ? 264  LEU A CG  1 
ATOM   478  C CD1 . LEU A 1 142  ? 152.909 131.139 185.199 1.00 75.27  ? 264  LEU A CD1 1 
ATOM   479  C CD2 . LEU A 1 142  ? 150.650 131.829 184.396 1.00 78.77  ? 264  LEU A CD2 1 
ATOM   480  N N   . LYS A 1 143  ? 149.131 127.780 187.468 1.00 94.34  ? 265  LYS A N   1 
ATOM   481  C CA  . LYS A 1 143  ? 148.580 126.405 187.485 1.00 96.54  ? 265  LYS A CA  1 
ATOM   482  C C   . LYS A 1 143  ? 147.090 126.446 187.825 1.00 99.34  ? 265  LYS A C   1 
ATOM   483  O O   . LYS A 1 143  ? 146.313 125.782 187.129 1.00 102.10 ? 265  LYS A O   1 
ATOM   484  C CB  . LYS A 1 143  ? 149.365 125.548 188.479 1.00 98.29  ? 265  LYS A CB  1 
ATOM   485  C CG  . LYS A 1 143  ? 150.845 125.388 188.165 1.00 96.91  ? 265  LYS A CG  1 
ATOM   486  C CD  . LYS A 1 143  ? 151.472 124.233 188.907 1.00 99.97  ? 265  LYS A CD  1 
ATOM   487  C CE  . LYS A 1 143  ? 150.911 122.891 188.487 1.00 105.22 ? 265  LYS A CE  1 
ATOM   488  N NZ  . LYS A 1 143  ? 151.575 121.774 189.199 1.00 107.00 ? 265  LYS A NZ  1 
ATOM   489  N N   . GLU A 1 144  ? 146.710 127.211 188.845 1.00 96.19  ? 266  GLU A N   1 
ATOM   490  C CA  . GLU A 1 144  ? 145.282 127.331 189.234 1.00 98.58  ? 266  GLU A CA  1 
ATOM   491  C C   . GLU A 1 144  ? 144.563 128.156 188.170 1.00 97.37  ? 266  GLU A C   1 
ATOM   492  O O   . GLU A 1 144  ? 143.327 128.253 188.252 1.00 100.67 ? 266  GLU A O   1 
ATOM   493  C CB  . GLU A 1 144  ? 145.128 127.905 190.640 1.00 100.42 ? 266  GLU A CB  1 
ATOM   494  C CG  . GLU A 1 144  ? 145.032 126.855 191.730 1.00 106.07 ? 266  GLU A CG  1 
ATOM   495  C CD  . GLU A 1 144  ? 146.345 126.298 192.259 1.00 107.64 ? 266  GLU A CD  1 
ATOM   496  O OE1 . GLU A 1 144  ? 147.329 126.260 191.497 1.00 103.70 ? 266  GLU A OE1 1 
ATOM   497  O OE2 . GLU A 1 144  ? 146.379 125.907 193.442 1.00 112.90 ? 266  GLU A OE2 1 
ATOM   498  N N   . LEU A 1 145  ? 145.313 128.777 187.259 1.00 93.71  ? 267  LEU A N   1 
ATOM   499  C CA  . LEU A 1 145  ? 144.711 129.540 186.133 1.00 95.75  ? 267  LEU A CA  1 
ATOM   500  C C   . LEU A 1 145  ? 143.850 130.685 186.662 1.00 97.09  ? 267  LEU A C   1 
ATOM   501  O O   . LEU A 1 145  ? 142.833 130.996 186.022 1.00 97.18  ? 267  LEU A O   1 
ATOM   502  C CB  . LEU A 1 145  ? 143.908 128.591 185.240 1.00 97.06  ? 267  LEU A CB  1 
ATOM   503  C CG  . LEU A 1 145  ? 144.738 127.627 184.396 1.00 99.39  ? 267  LEU A CG  1 
ATOM   504  C CD1 . LEU A 1 145  ? 143.876 126.493 183.863 1.00 101.47 ? 267  LEU A CD1 1 
ATOM   505  C CD2 . LEU A 1 145  ? 145.423 128.361 183.255 1.00 95.46  ? 267  LEU A CD2 1 
ATOM   506  N N   . GLU A 1 146  ? 144.257 131.300 187.772 1.00 94.72  ? 268  GLU A N   1 
ATOM   507  C CA  . GLU A 1 146  ? 143.529 132.484 188.284 1.00 93.00  ? 268  GLU A CA  1 
ATOM   508  C C   . GLU A 1 146  ? 144.320 133.733 187.897 1.00 92.73  ? 268  GLU A C   1 
ATOM   509  O O   . GLU A 1 146  ? 145.534 133.614 187.704 1.00 93.46  ? 268  GLU A O   1 
ATOM   510  C CB  . GLU A 1 146  ? 143.402 132.379 189.800 1.00 92.69  ? 268  GLU A CB  1 
ATOM   511  C CG  . GLU A 1 146  ? 144.651 131.848 190.465 1.00 92.33  ? 268  GLU A CG  1 
ATOM   512  C CD  . GLU A 1 146  ? 144.513 131.614 191.955 1.00 94.43  ? 268  GLU A CD  1 
ATOM   513  O OE1 . GLU A 1 146  ? 143.498 132.049 192.528 1.00 94.94  ? 268  GLU A OE1 1 
ATOM   514  O OE2 . GLU A 1 146  ? 145.417 130.988 192.532 1.00 94.20  ? 268  GLU A OE2 1 
ATOM   515  N N   . SER A 1 147  ? 143.660 134.880 187.764 1.00 93.02  ? 269  SER A N   1 
ATOM   516  C CA  . SER A 1 147  ? 144.380 136.110 187.498 1.00 91.21  ? 269  SER A CA  1 
ATOM   517  C C   . SER A 1 147  ? 145.253 136.477 188.693 1.00 92.23  ? 269  SER A C   1 
ATOM   518  O O   . SER A 1 147  ? 145.141 135.903 189.781 1.00 95.24  ? 269  SER A O   1 
ATOM   519  C CB  . SER A 1 147  ? 143.408 137.242 187.176 1.00 92.28  ? 269  SER A CB  1 
ATOM   520  O OG  . SER A 1 147  ? 144.076 138.315 186.537 1.00 94.37  ? 269  SER A OG  1 
ATOM   521  N N   . CYS A 1 148  ? 146.149 137.442 188.478 1.00 89.73  ? 270  CYS A N   1 
ATOM   522  C CA  . CYS A 1 148  ? 146.963 137.955 189.571 1.00 86.13  ? 270  CYS A CA  1 
ATOM   523  C C   . CYS A 1 148  ? 146.164 138.829 190.523 1.00 86.99  ? 270  CYS A C   1 
ATOM   524  O O   . CYS A 1 148  ? 146.513 138.913 191.703 1.00 88.43  ? 270  CYS A O   1 
ATOM   525  C CB  . CYS A 1 148  ? 148.151 138.748 189.027 1.00 83.04  ? 270  CYS A CB  1 
ATOM   526  S SG  . CYS A 1 148  ? 149.487 137.738 188.358 1.00 96.41  ? 270  CYS A SG  1 
ATOM   527  N N   . GLN A 1 149  ? 145.107 139.480 190.036 1.00 88.04  ? 271  GLN A N   1 
ATOM   528  C CA  . GLN A 1 149  ? 144.213 140.232 190.905 1.00 87.00  ? 271  GLN A CA  1 
ATOM   529  C C   . GLN A 1 149  ? 143.335 139.313 191.740 1.00 87.37  ? 271  GLN A C   1 
ATOM   530  O O   . GLN A 1 149  ? 142.977 139.662 192.869 1.00 87.66  ? 271  GLN A O   1 
ATOM   531  C CB  . GLN A 1 149  ? 143.340 141.168 190.072 1.00 85.57  ? 271  GLN A CB  1 
ATOM   532  C CG  . GLN A 1 149  ? 144.044 141.737 188.862 1.00 88.58  ? 271  GLN A CG  1 
ATOM   533  C CD  . GLN A 1 149  ? 143.107 142.495 187.958 1.00 97.96  ? 271  GLN A CD  1 
ATOM   534  O OE1 . GLN A 1 149  ? 141.982 142.813 188.339 1.00 100.06 ? 271  GLN A OE1 1 
ATOM   535  N NE2 . GLN A 1 149  ? 143.558 142.775 186.743 1.00 99.19  ? 271  GLN A NE2 1 
ATOM   536  N N   . GLU A 1 150  ? 142.970 138.152 191.194 1.00 89.33  ? 272  GLU A N   1 
ATOM   537  C CA  . GLU A 1 150  ? 142.200 137.166 191.942 1.00 90.27  ? 272  GLU A CA  1 
ATOM   538  C C   . GLU A 1 150  ? 143.062 136.466 192.985 1.00 88.06  ? 272  GLU A C   1 
ATOM   539  O O   . GLU A 1 150  ? 142.585 136.175 194.089 1.00 89.64  ? 272  GLU A O   1 
ATOM   540  C CB  . GLU A 1 150  ? 141.575 136.162 190.962 1.00 92.83  ? 272  GLU A CB  1 
ATOM   541  C CG  . GLU A 1 150  ? 140.700 135.074 191.572 1.00 97.69  ? 272  GLU A CG  1 
ATOM   542  C CD  . GLU A 1 150  ? 140.159 134.112 190.532 1.00 101.34 ? 272  GLU A CD  1 
ATOM   543  O OE1 . GLU A 1 150  ? 139.696 133.016 190.915 1.00 99.38  ? 272  GLU A OE1 1 
ATOM   544  O OE2 . GLU A 1 150  ? 140.194 134.454 189.332 1.00 104.07 ? 272  GLU A OE2 1 
ATOM   545  N N   . ALA A 1 151  ? 144.336 136.226 192.666 1.00 86.09  ? 273  ALA A N   1 
ATOM   546  C CA  . ALA A 1 151  ? 145.261 135.621 193.619 1.00 86.32  ? 273  ALA A CA  1 
ATOM   547  C C   . ALA A 1 151  ? 145.670 136.587 194.723 1.00 90.38  ? 273  ALA A C   1 
ATOM   548  O O   . ALA A 1 151  ? 145.811 136.173 195.877 1.00 91.36  ? 273  ALA A O   1 
ATOM   549  C CB  . ALA A 1 151  ? 146.504 135.109 192.892 1.00 87.08  ? 273  ALA A CB  1 
ATOM   550  N N   . CYS A 1 152  ? 145.860 137.862 194.398 1.00 91.23  ? 274  CYS A N   1 
ATOM   551  C CA  . CYS A 1 152  ? 146.220 138.864 195.398 1.00 85.28  ? 274  CYS A CA  1 
ATOM   552  C C   . CYS A 1 152  ? 144.977 139.646 195.809 1.00 87.43  ? 274  CYS A C   1 
ATOM   553  O O   . CYS A 1 152  ? 144.779 140.809 195.457 1.00 86.53  ? 274  CYS A O   1 
ATOM   554  C CB  . CYS A 1 152  ? 147.306 139.780 194.855 1.00 81.98  ? 274  CYS A CB  1 
ATOM   555  S SG  . CYS A 1 152  ? 148.882 138.966 194.740 1.00 96.13  ? 274  CYS A SG  1 
ATOM   556  N N   . LEU A 1 153  ? 144.135 138.974 196.585 1.00 89.84  ? 275  LEU A N   1 
ATOM   557  C CA  . LEU A 1 153  ? 142.890 139.544 197.082 1.00 89.80  ? 275  LEU A CA  1 
ATOM   558  C C   . LEU A 1 153  ? 142.983 139.594 198.598 1.00 91.88  ? 275  LEU A C   1 
ATOM   559  O O   . LEU A 1 153  ? 142.836 138.568 199.269 1.00 93.01  ? 275  LEU A O   1 
ATOM   560  C CB  . LEU A 1 153  ? 141.687 138.722 196.623 1.00 89.16  ? 275  LEU A CB  1 
ATOM   561  C CG  . LEU A 1 153  ? 140.286 139.340 196.681 1.00 91.48  ? 275  LEU A CG  1 
ATOM   562  C CD1 . LEU A 1 153  ? 140.270 140.796 196.230 1.00 92.81  ? 275  LEU A CD1 1 
ATOM   563  C CD2 . LEU A 1 153  ? 139.322 138.514 195.846 1.00 89.30  ? 275  LEU A CD2 1 
ATOM   564  N N   . SER A 1 154  ? 143.230 140.783 199.135 1.00 92.05  ? 276  SER A N   1 
ATOM   565  C CA  . SER A 1 154  ? 143.413 140.979 200.563 1.00 93.71  ? 276  SER A CA  1 
ATOM   566  C C   . SER A 1 154  ? 142.221 141.729 201.135 1.00 96.74  ? 276  SER A C   1 
ATOM   567  O O   . SER A 1 154  ? 141.672 142.626 200.492 1.00 97.06  ? 276  SER A O   1 
ATOM   568  C CB  . SER A 1 154  ? 144.703 141.749 200.852 1.00 91.86  ? 276  SER A CB  1 
ATOM   569  O OG  . SER A 1 154  ? 144.926 141.862 202.245 1.00 93.81  ? 276  SER A OG  1 
ATOM   570  N N   . LEU A 1 155  ? 141.815 141.340 202.344 1.00 98.00  ? 277  LEU A N   1 
ATOM   571  C CA  . LEU A 1 155  ? 140.711 142.025 203.007 1.00 99.23  ? 277  LEU A CA  1 
ATOM   572  C C   . LEU A 1 155  ? 141.160 143.362 203.581 1.00 98.20  ? 277  LEU A C   1 
ATOM   573  O O   . LEU A 1 155  ? 140.344 144.276 203.754 1.00 98.12  ? 277  LEU A O   1 
ATOM   574  C CB  . LEU A 1 155  ? 140.128 141.135 204.102 1.00 102.46 ? 277  LEU A CB  1 
ATOM   575  C CG  . LEU A 1 155  ? 139.668 139.748 203.650 1.00 103.39 ? 277  LEU A CG  1 
ATOM   576  C CD1 . LEU A 1 155  ? 139.261 138.903 204.845 1.00 106.99 ? 277  LEU A CD1 1 
ATOM   577  C CD2 . LEU A 1 155  ? 138.527 139.858 202.653 1.00 99.93  ? 277  LEU A CD2 1 
ATOM   578  N N   . GLN A 1 156  ? 142.450 143.487 203.900 1.00 96.74  ? 278  GLN A N   1 
ATOM   579  C CA  . GLN A 1 156  ? 142.976 144.742 204.430 1.00 93.78  ? 278  GLN A CA  1 
ATOM   580  C C   . GLN A 1 156  ? 143.114 145.791 203.334 1.00 91.92  ? 278  GLN A C   1 
ATOM   581  O O   . GLN A 1 156  ? 142.784 146.964 203.536 1.00 93.34  ? 278  GLN A O   1 
ATOM   582  C CB  . GLN A 1 156  ? 144.320 144.496 205.113 1.00 95.42  ? 278  GLN A CB  1 
ATOM   583  C CG  . GLN A 1 156  ? 144.318 143.318 206.069 1.00 99.15  ? 278  GLN A CG  1 
ATOM   584  C CD  . GLN A 1 156  ? 145.713 142.811 206.369 1.00 102.24 ? 278  GLN A CD  1 
ATOM   585  O OE1 . GLN A 1 156  ? 146.705 143.397 205.935 1.00 104.51 ? 278  GLN A OE1 1 
ATOM   586  N NE2 . GLN A 1 156  ? 145.797 141.717 207.116 1.00 101.51 ? 278  GLN A NE2 1 
ATOM   587  N N   . PHE A 1 157  ? 143.599 145.388 202.164 1.00 93.01  ? 279  PHE A N   1 
ATOM   588  C CA  . PHE A 1 157  ? 143.797 146.291 201.035 1.00 91.86  ? 279  PHE A CA  1 
ATOM   589  C C   . PHE A 1 157  ? 142.786 145.933 199.954 1.00 93.89  ? 279  PHE A C   1 
ATOM   590  O O   . PHE A 1 157  ? 142.992 144.985 199.191 1.00 91.93  ? 279  PHE A O   1 
ATOM   591  C CB  . PHE A 1 157  ? 145.228 146.208 200.512 1.00 87.71  ? 279  PHE A CB  1 
ATOM   592  C CG  . PHE A 1 157  ? 146.261 146.624 201.517 1.00 88.92  ? 279  PHE A CG  1 
ATOM   593  C CD1 . PHE A 1 157  ? 146.558 147.975 201.701 1.00 89.50  ? 279  PHE A CD1 1 
ATOM   594  C CD2 . PHE A 1 157  ? 146.934 145.668 202.281 1.00 89.66  ? 279  PHE A CD2 1 
ATOM   595  C CE1 . PHE A 1 157  ? 147.514 148.372 202.635 1.00 89.88  ? 279  PHE A CE1 1 
ATOM   596  C CE2 . PHE A 1 157  ? 147.891 146.051 203.220 1.00 90.23  ? 279  PHE A CE2 1 
ATOM   597  C CZ  . PHE A 1 157  ? 148.180 147.407 203.393 1.00 89.92  ? 279  PHE A CZ  1 
ATOM   598  N N   . TYR A 1 158  ? 141.704 146.698 199.893 1.00 95.87  ? 280  TYR A N   1 
ATOM   599  C CA  . TYR A 1 158  ? 140.572 146.468 199.014 1.00 96.23  ? 280  TYR A CA  1 
ATOM   600  C C   . TYR A 1 158  ? 140.342 147.714 198.171 1.00 96.54  ? 280  TYR A C   1 
ATOM   601  O O   . TYR A 1 158  ? 140.450 148.832 198.685 1.00 96.27  ? 280  TYR A O   1 
ATOM   602  C CB  . TYR A 1 158  ? 139.314 146.145 199.840 1.00 99.15  ? 280  TYR A CB  1 
ATOM   603  C CG  . TYR A 1 158  ? 138.274 145.327 199.114 1.00 102.04 ? 280  TYR A CG  1 
ATOM   604  C CD1 . TYR A 1 158  ? 138.460 143.955 198.910 1.00 102.28 ? 280  TYR A CD1 1 
ATOM   605  C CD2 . TYR A 1 158  ? 137.118 145.932 198.604 1.00 101.89 ? 280  TYR A CD2 1 
ATOM   606  C CE1 . TYR A 1 158  ? 137.509 143.194 198.227 1.00 103.82 ? 280  TYR A CE1 1 
ATOM   607  C CE2 . TYR A 1 158  ? 136.159 145.184 197.919 1.00 103.38 ? 280  TYR A CE2 1 
ATOM   608  C CZ  . TYR A 1 158  ? 136.366 143.819 197.738 1.00 105.21 ? 280  TYR A CZ  1 
ATOM   609  O OH  . TYR A 1 158  ? 135.424 143.076 197.066 1.00 106.49 ? 280  TYR A OH  1 
ATOM   610  N N   . PRO A 1 159  ? 140.029 147.568 196.867 1.00 94.40  ? 281  PRO A N   1 
ATOM   611  C CA  . PRO A 1 159  ? 139.845 146.341 196.073 1.00 91.61  ? 281  PRO A CA  1 
ATOM   612  C C   . PRO A 1 159  ? 141.112 145.757 195.464 1.00 91.16  ? 281  PRO A C   1 
ATOM   613  O O   . PRO A 1 159  ? 141.113 144.596 195.071 1.00 92.45  ? 281  PRO A O   1 
ATOM   614  C CB  . PRO A 1 159  ? 138.869 146.796 194.985 1.00 90.66  ? 281  PRO A CB  1 
ATOM   615  C CG  . PRO A 1 159  ? 139.199 148.237 194.764 1.00 90.56  ? 281  PRO A CG  1 
ATOM   616  C CD  . PRO A 1 159  ? 139.718 148.775 196.078 1.00 92.71  ? 281  PRO A CD  1 
ATOM   617  N N   . TYR A 1 160  ? 142.203 146.511 195.369 1.00 89.47  ? 282  TYR A N   1 
ATOM   618  C CA  . TYR A 1 160  ? 143.407 146.041 194.703 1.00 83.69  ? 282  TYR A CA  1 
ATOM   619  C C   . TYR A 1 160  ? 144.621 146.293 195.578 1.00 82.35  ? 282  TYR A C   1 
ATOM   620  O O   . TYR A 1 160  ? 144.754 147.366 196.173 1.00 84.25  ? 282  TYR A O   1 
ATOM   621  C CB  . TYR A 1 160  ? 143.591 146.724 193.350 1.00 81.08  ? 282  TYR A CB  1 
ATOM   622  C CG  . TYR A 1 160  ? 142.440 146.551 192.391 1.00 81.53  ? 282  TYR A CG  1 
ATOM   623  C CD1 . TYR A 1 160  ? 142.185 145.307 191.802 1.00 84.37  ? 282  TYR A CD1 1 
ATOM   624  C CD2 . TYR A 1 160  ? 141.624 147.634 192.053 1.00 83.74  ? 282  TYR A CD2 1 
ATOM   625  C CE1 . TYR A 1 160  ? 141.126 145.140 190.912 1.00 86.10  ? 282  TYR A CE1 1 
ATOM   626  C CE2 . TYR A 1 160  ? 140.566 147.483 191.161 1.00 85.64  ? 282  TYR A CE2 1 
ATOM   627  C CZ  . TYR A 1 160  ? 140.327 146.234 190.597 1.00 88.79  ? 282  TYR A CZ  1 
ATOM   628  O OH  . TYR A 1 160  ? 139.284 146.078 189.716 1.00 93.20  ? 282  TYR A OH  1 
ATOM   629  N N   . ASP A 1 161  ? 145.502 145.299 195.649 1.00 79.39  ? 283  ASP A N   1 
ATOM   630  C CA  . ASP A 1 161  ? 146.790 145.404 196.328 1.00 75.47  ? 283  ASP A CA  1 
ATOM   631  C C   . ASP A 1 161  ? 147.844 145.546 195.237 1.00 73.73  ? 283  ASP A C   1 
ATOM   632  O O   . ASP A 1 161  ? 148.213 144.570 194.591 1.00 78.25  ? 283  ASP A O   1 
ATOM   633  C CB  . ASP A 1 161  ? 147.036 144.179 197.201 1.00 74.53  ? 283  ASP A CB  1 
ATOM   634  C CG  . ASP A 1 161  ? 148.052 144.427 198.293 1.00 80.87  ? 283  ASP A CG  1 
ATOM   635  O OD1 . ASP A 1 161  ? 148.627 145.532 198.342 1.00 83.76  ? 283  ASP A OD1 1 
ATOM   636  O OD2 . ASP A 1 161  ? 148.281 143.508 199.104 1.00 83.55  ? 283  ASP A OD2 1 
ATOM   637  N N   . MET A 1 162  ? 148.311 146.782 195.038 1.00 71.75  ? 284  MET A N   1 
ATOM   638  C CA  . MET A 1 162  ? 149.280 147.105 193.983 1.00 68.44  ? 284  MET A CA  1 
ATOM   639  C C   . MET A 1 162  ? 150.663 146.427 194.005 1.00 67.14  ? 284  MET A C   1 
ATOM   640  O O   . MET A 1 162  ? 151.106 146.043 192.904 1.00 68.30  ? 284  MET A O   1 
ATOM   641  C CB  . MET A 1 162  ? 149.423 148.636 193.897 1.00 74.89  ? 284  MET A CB  1 
ATOM   642  C CG  . MET A 1 162  ? 148.321 149.371 193.156 1.00 73.95  ? 284  MET A CG  1 
ATOM   643  S SD  . MET A 1 162  ? 148.173 148.780 191.458 1.00 74.23  ? 284  MET A SD  1 
ATOM   644  C CE  . MET A 1 162  ? 146.598 147.965 191.470 1.00 71.00  ? 284  MET A CE  1 
ATOM   645  N N   . PRO A 1 163  ? 151.398 146.255 195.139 1.00 68.60  ? 285  PRO A N   1 
ATOM   646  C CA  . PRO A 1 163  ? 152.681 145.529 195.025 1.00 70.53  ? 285  PRO A CA  1 
ATOM   647  C C   . PRO A 1 163  ? 152.539 144.034 194.801 1.00 71.74  ? 285  PRO A C   1 
ATOM   648  O O   . PRO A 1 163  ? 153.389 143.463 194.107 1.00 75.20  ? 285  PRO A O   1 
ATOM   649  C CB  . PRO A 1 163  ? 153.377 145.815 196.360 1.00 72.90  ? 285  PRO A CB  1 
ATOM   650  C CG  . PRO A 1 163  ? 152.730 146.978 196.889 1.00 70.08  ? 285  PRO A CG  1 
ATOM   651  C CD  . PRO A 1 163  ? 151.325 146.835 196.502 1.00 71.38  ? 285  PRO A CD  1 
ATOM   652  N N   . CYS A 1 164  ? 151.458 143.415 195.295 1.00 69.84  ? 286  CYS A N   1 
ATOM   653  C CA  . CYS A 1 164  ? 151.269 141.977 195.133 1.00 66.57  ? 286  CYS A CA  1 
ATOM   654  C C   . CYS A 1 164  ? 150.875 141.645 193.699 1.00 67.54  ? 286  CYS A C   1 
ATOM   655  O O   . CYS A 1 164  ? 151.427 140.709 193.100 1.00 74.29  ? 286  CYS A O   1 
ATOM   656  C CB  . CYS A 1 164  ? 150.214 141.482 196.133 1.00 72.72  ? 286  CYS A CB  1 
ATOM   657  S SG  . CYS A 1 164  ? 149.932 139.673 196.328 1.00 93.37  ? 286  CYS A SG  1 
ATOM   658  N N   . ILE A 1 165  ? 149.967 142.448 193.130 1.00 66.58  ? 287  ILE A N   1 
ATOM   659  C CA  . ILE A 1 165  ? 149.508 142.292 191.751 1.00 66.02  ? 287  ILE A CA  1 
ATOM   660  C C   . ILE A 1 165  ? 150.630 142.622 190.773 1.00 64.86  ? 287  ILE A C   1 
ATOM   661  O O   . ILE A 1 165  ? 150.863 141.870 189.813 1.00 67.81  ? 287  ILE A O   1 
ATOM   662  C CB  . ILE A 1 165  ? 148.247 143.160 191.530 1.00 67.74  ? 287  ILE A CB  1 
ATOM   663  C CG1 . ILE A 1 165  ? 147.031 142.519 192.196 1.00 73.63  ? 287  ILE A CG1 1 
ATOM   664  C CG2 . ILE A 1 165  ? 147.915 143.394 190.062 1.00 72.41  ? 287  ILE A CG2 1 
ATOM   665  C CD1 . ILE A 1 165  ? 145.870 143.468 192.368 1.00 74.95  ? 287  ILE A CD1 1 
ATOM   666  N N   . GLY A 1 166  ? 151.405 143.677 191.073 1.00 65.85  ? 288  GLY A N   1 
ATOM   667  C CA  . GLY A 1 166  ? 152.531 144.055 190.227 1.00 61.65  ? 288  GLY A CA  1 
ATOM   668  C C   . GLY A 1 166  ? 153.685 143.066 190.237 1.00 61.10  ? 288  GLY A C   1 
ATOM   669  O O   . GLY A 1 166  ? 154.226 142.745 189.177 1.00 68.10  ? 288  GLY A O   1 
ATOM   670  N N   . ALA A 1 167  ? 154.006 142.505 191.413 1.00 60.30  ? 289  ALA A N   1 
ATOM   671  C CA  . ALA A 1 167  ? 155.052 141.489 191.525 1.00 60.26  ? 289  ALA A CA  1 
ATOM   672  C C   . ALA A 1 167  ? 154.633 140.170 190.886 1.00 65.02  ? 289  ALA A C   1 
ATOM   673  O O   . ALA A 1 167  ? 155.477 139.473 190.299 1.00 71.34  ? 289  ALA A O   1 
ATOM   674  C CB  . ALA A 1 167  ? 155.409 141.271 192.994 1.00 63.64  ? 289  ALA A CB  1 
ATOM   675  N N   . CYS A 1 168  ? 153.324 139.860 190.936 1.00 66.24  ? 290  CYS A N   1 
ATOM   676  C CA  . CYS A 1 168  ? 152.772 138.692 190.251 1.00 61.85  ? 290  CYS A CA  1 
ATOM   677  C C   . CYS A 1 168  ? 152.868 138.815 188.732 1.00 61.22  ? 290  CYS A C   1 
ATOM   678  O O   . CYS A 1 168  ? 153.251 137.851 188.061 1.00 65.68  ? 290  CYS A O   1 
ATOM   679  C CB  . CYS A 1 168  ? 151.320 138.486 190.679 1.00 66.28  ? 290  CYS A CB  1 
ATOM   680  S SG  . CYS A 1 168  ? 150.498 137.041 189.980 1.00 83.58  ? 290  CYS A SG  1 
ATOM   681  N N   . GLU A 1 169  ? 152.584 140.003 188.174 1.00 61.70  ? 291  GLU A N   1 
ATOM   682  C CA  . GLU A 1 169  ? 152.696 140.142 186.718 1.00 60.90  ? 291  GLU A CA  1 
ATOM   683  C C   . GLU A 1 169  ? 154.131 140.237 186.195 1.00 59.36  ? 291  GLU A C   1 
ATOM   684  O O   . GLU A 1 169  ? 154.390 139.701 185.105 1.00 64.54  ? 291  GLU A O   1 
ATOM   685  C CB  . GLU A 1 169  ? 151.875 141.321 186.193 1.00 64.98  ? 291  GLU A CB  1 
ATOM   686  C CG  . GLU A 1 169  ? 150.422 141.298 186.589 1.00 67.74  ? 291  GLU A CG  1 
ATOM   687  C CD  . GLU A 1 169  ? 149.563 140.542 185.600 1.00 77.06  ? 291  GLU A CD  1 
ATOM   688  O OE1 . GLU A 1 169  ? 150.029 140.306 184.468 1.00 81.77  ? 291  GLU A OE1 1 
ATOM   689  O OE2 . GLU A 1 169  ? 148.423 140.179 185.954 1.00 80.69  ? 291  GLU A OE2 1 
ATOM   690  N N   . MET A 1 170  ? 155.077 140.872 186.924 1.00 58.15  ? 292  MET A N   1 
ATOM   691  C CA  . MET A 1 170  ? 156.476 140.786 186.473 1.00 59.15  ? 292  MET A CA  1 
ATOM   692  C C   . MET A 1 170  ? 157.086 139.399 186.644 1.00 59.83  ? 292  MET A C   1 
ATOM   693  O O   . MET A 1 170  ? 157.899 138.994 185.804 1.00 65.40  ? 292  MET A O   1 
ATOM   694  C CB  . MET A 1 170  ? 157.415 141.806 187.134 1.00 62.08  ? 292  MET A CB  1 
ATOM   695  C CG  . MET A 1 170  ? 156.935 143.200 187.382 1.00 61.08  ? 292  MET A CG  1 
ATOM   696  S SD  . MET A 1 170  ? 158.290 144.304 187.811 1.00 79.57  ? 292  MET A SD  1 
ATOM   697  C CE  . MET A 1 170  ? 159.382 144.074 186.416 1.00 69.72  ? 292  MET A CE  1 
ATOM   698  N N   . ALA A 1 171  ? 156.670 138.635 187.666 1.00 58.26  ? 293  ALA A N   1 
ATOM   699  C CA  . ALA A 1 171  ? 157.170 137.269 187.798 1.00 56.69  ? 293  ALA A CA  1 
ATOM   700  C C   . ALA A 1 171  ? 156.563 136.336 186.753 1.00 58.89  ? 293  ALA A C   1 
ATOM   701  O O   . ALA A 1 171  ? 157.257 135.451 186.231 1.00 65.49  ? 293  ALA A O   1 
ATOM   702  C CB  . ALA A 1 171  ? 156.906 136.755 189.208 1.00 59.71  ? 293  ALA A CB  1 
ATOM   703  N N   . GLN A 1 172  ? 155.299 136.572 186.375 1.00 59.61  ? 294  GLN A N   1 
ATOM   704  C CA  . GLN A 1 172  ? 154.664 135.769 185.332 1.00 57.70  ? 294  GLN A CA  1 
ATOM   705  C C   . GLN A 1 172  ? 155.230 136.066 183.945 1.00 58.06  ? 294  GLN A C   1 
ATOM   706  O O   . GLN A 1 172  ? 155.461 135.132 183.164 1.00 64.04  ? 294  GLN A O   1 
ATOM   707  C CB  . GLN A 1 172  ? 153.154 135.977 185.350 1.00 61.00  ? 294  GLN A CB  1 
ATOM   708  C CG  . GLN A 1 172  ? 152.428 135.085 186.333 1.00 64.92  ? 294  GLN A CG  1 
ATOM   709  C CD  . GLN A 1 172  ? 150.935 135.240 186.247 1.00 68.24  ? 294  GLN A CD  1 
ATOM   710  O OE1 . GLN A 1 172  ? 150.429 136.044 185.469 1.00 67.89  ? 294  GLN A OE1 1 
ATOM   711  N NE2 . GLN A 1 172  ? 150.213 134.472 187.050 1.00 74.14  ? 294  GLN A NE2 1 
ATOM   712  N N   . ARG A 1 173  ? 155.523 137.339 183.634 1.00 55.91  ? 295  ARG A N   1 
ATOM   713  C CA  . ARG A 1 173  ? 156.111 137.592 182.321 1.00 57.49  ? 295  ARG A CA  1 
ATOM   714  C C   . ARG A 1 173  ? 157.608 137.282 182.288 1.00 59.86  ? 295  ARG A C   1 
ATOM   715  O O   . ARG A 1 173  ? 158.144 137.039 181.202 1.00 63.59  ? 295  ARG A O   1 
ATOM   716  C CB  . ARG A 1 173  ? 155.858 139.019 181.842 1.00 59.66  ? 295  ARG A CB  1 
ATOM   717  C CG  . ARG A 1 173  ? 156.673 140.072 182.506 1.00 63.09  ? 295  ARG A CG  1 
ATOM   718  C CD  . ARG A 1 173  ? 156.944 141.187 181.522 1.00 65.48  ? 295  ARG A CD  1 
ATOM   719  N NE  . ARG A 1 173  ? 157.954 140.826 180.534 1.00 73.55  ? 295  ARG A NE  1 
ATOM   720  C CZ  . ARG A 1 173  ? 159.264 140.939 180.714 1.00 75.75  ? 295  ARG A CZ  1 
ATOM   721  N NH1 . ARG A 1 173  ? 159.772 141.371 181.855 1.00 69.92  ? 295  ARG A NH1 1 
ATOM   722  N NH2 . ARG A 1 173  ? 160.084 140.596 179.726 1.00 74.56  ? 295  ARG A NH2 1 
ATOM   723  N N   . ASP A 1 174  ? 158.282 137.215 183.450 1.00 60.90  ? 296  ASP A N   1 
ATOM   724  C CA  . ASP A 1 174  ? 159.650 136.695 183.482 1.00 60.97  ? 296  ASP A CA  1 
ATOM   725  C C   . ASP A 1 174  ? 159.684 135.195 183.226 1.00 62.23  ? 296  ASP A C   1 
ATOM   726  O O   . ASP A 1 174  ? 160.593 134.701 182.537 1.00 67.30  ? 296  ASP A O   1 
ATOM   727  C CB  . ASP A 1 174  ? 160.307 137.009 184.824 1.00 67.66  ? 296  ASP A CB  1 
ATOM   728  C CG  . ASP A 1 174  ? 160.914 138.392 184.869 1.00 76.67  ? 296  ASP A CG  1 
ATOM   729  O OD1 . ASP A 1 174  ? 160.914 139.082 183.829 1.00 78.33  ? 296  ASP A OD1 1 
ATOM   730  O OD2 . ASP A 1 174  ? 161.397 138.787 185.950 1.00 79.81  ? 296  ASP A OD2 1 
ATOM   731  N N   . TYR A 1 175  ? 158.685 134.469 183.763 1.00 61.21  ? 297  TYR A N   1 
ATOM   732  C CA  . TYR A 1 175  ? 158.534 133.042 183.484 1.00 60.68  ? 297  TYR A CA  1 
ATOM   733  C C   . TYR A 1 175  ? 158.209 132.776 182.023 1.00 61.12  ? 297  TYR A C   1 
ATOM   734  O O   . TYR A 1 175  ? 158.765 131.848 181.424 1.00 68.46  ? 297  TYR A O   1 
ATOM   735  C CB  . TYR A 1 175  ? 157.439 132.439 184.359 1.00 64.13  ? 297  TYR A CB  1 
ATOM   736  C CG  . TYR A 1 175  ? 157.178 130.973 184.077 1.00 67.31  ? 297  TYR A CG  1 
ATOM   737  C CD1 . TYR A 1 175  ? 158.126 130.006 184.423 1.00 74.23  ? 297  TYR A CD1 1 
ATOM   738  C CD2 . TYR A 1 175  ? 155.983 130.552 183.475 1.00 68.56  ? 297  TYR A CD2 1 
ATOM   739  C CE1 . TYR A 1 175  ? 157.903 128.656 184.170 1.00 79.57  ? 297  TYR A CE1 1 
ATOM   740  C CE2 . TYR A 1 175  ? 155.749 129.204 183.214 1.00 76.32  ? 297  TYR A CE2 1 
ATOM   741  C CZ  . TYR A 1 175  ? 156.715 128.269 183.566 1.00 81.62  ? 297  TYR A CZ  1 
ATOM   742  O OH  . TYR A 1 175  ? 156.492 126.936 183.317 1.00 91.17  ? 297  TYR A OH  1 
ATOM   743  N N   . TRP A 1 176  ? 157.337 133.595 181.425 1.00 60.77  ? 298  TRP A N   1 
ATOM   744  C CA  . TRP A 1 176  ? 156.999 133.376 180.022 1.00 58.91  ? 298  TRP A CA  1 
ATOM   745  C C   . TRP A 1 176  ? 158.112 133.836 179.086 1.00 58.57  ? 298  TRP A C   1 
ATOM   746  O O   . TRP A 1 176  ? 158.260 133.279 177.998 1.00 61.62  ? 298  TRP A O   1 
ATOM   747  C CB  . TRP A 1 176  ? 155.668 134.040 179.655 1.00 58.43  ? 298  TRP A CB  1 
ATOM   748  C CG  . TRP A 1 176  ? 154.395 133.411 180.249 1.00 60.64  ? 298  TRP A CG  1 
ATOM   749  C CD1 . TRP A 1 176  ? 153.438 134.073 180.959 1.00 62.25  ? 298  TRP A CD1 1 
ATOM   750  C CD2 . TRP A 1 176  ? 153.922 132.045 180.135 1.00 63.04  ? 298  TRP A CD2 1 
ATOM   751  N NE1 . TRP A 1 176  ? 152.431 133.220 181.324 1.00 64.24  ? 298  TRP A NE1 1 
ATOM   752  C CE2 . TRP A 1 176  ? 152.698 131.973 180.831 1.00 65.99  ? 298  TRP A CE2 1 
ATOM   753  C CE3 . TRP A 1 176  ? 154.417 130.877 179.527 1.00 67.71  ? 298  TRP A CE3 1 
ATOM   754  C CZ2 . TRP A 1 176  ? 151.966 130.790 180.936 1.00 72.33  ? 298  TRP A CZ2 1 
ATOM   755  C CZ3 . TRP A 1 176  ? 153.692 129.705 179.637 1.00 70.84  ? 298  TRP A CZ3 1 
ATOM   756  C CH2 . TRP A 1 176  ? 152.478 129.672 180.334 1.00 76.04  ? 298  TRP A CH2 1 
ATOM   757  N N   . HIS A 1 177  ? 158.954 134.783 179.519 1.00 62.43  ? 299  HIS A N   1 
ATOM   758  C CA  . HIS A 1 177  ? 160.120 135.155 178.718 1.00 61.00  ? 299  HIS A CA  1 
ATOM   759  C C   . HIS A 1 177  ? 161.193 134.068 178.743 1.00 62.43  ? 299  HIS A C   1 
ATOM   760  O O   . HIS A 1 177  ? 161.807 133.776 177.706 1.00 68.59  ? 299  HIS A O   1 
ATOM   761  C CB  . HIS A 1 177  ? 160.685 136.484 179.211 1.00 66.16  ? 299  HIS A CB  1 
ATOM   762  C CG  . HIS A 1 177  ? 161.945 136.900 178.520 1.00 71.40  ? 299  HIS A CG  1 
ATOM   763  N ND1 . HIS A 1 177  ? 161.951 137.484 177.273 1.00 75.23  ? 299  HIS A ND1 1 
ATOM   764  C CD2 . HIS A 1 177  ? 163.240 136.824 178.907 1.00 73.90  ? 299  HIS A CD2 1 
ATOM   765  C CE1 . HIS A 1 177  ? 163.196 137.747 176.919 1.00 79.31  ? 299  HIS A CE1 1 
ATOM   766  N NE2 . HIS A 1 177  ? 163.998 137.355 177.892 1.00 80.66  ? 299  HIS A NE2 1 
ATOM   767  N N   . LEU A 1 178  ? 161.390 133.418 179.901 1.00 62.72  ? 300  LEU A N   1 
ATOM   768  C CA  . LEU A 1 178  ? 162.318 132.288 179.964 1.00 60.64  ? 300  LEU A CA  1 
ATOM   769  C C   . LEU A 1 178  ? 161.796 131.046 179.241 1.00 63.83  ? 300  LEU A C   1 
ATOM   770  O O   . LEU A 1 178  ? 162.586 130.330 178.612 1.00 69.33  ? 300  LEU A O   1 
ATOM   771  C CB  . LEU A 1 178  ? 162.647 131.947 181.416 1.00 64.98  ? 300  LEU A CB  1 
ATOM   772  C CG  . LEU A 1 178  ? 163.590 132.914 182.129 1.00 68.16  ? 300  LEU A CG  1 
ATOM   773  C CD1 . LEU A 1 178  ? 163.836 132.455 183.547 1.00 73.76  ? 300  LEU A CD1 1 
ATOM   774  C CD2 . LEU A 1 178  ? 164.904 133.047 181.381 1.00 70.42  ? 300  LEU A CD2 1 
ATOM   775  N N   . GLN A 1 179  ? 160.485 130.796 179.267 1.00 63.99  ? 301  GLN A N   1 
ATOM   776  C CA  . GLN A 1 179  ? 159.921 129.734 178.442 1.00 63.23  ? 301  GLN A CA  1 
ATOM   777  C C   . GLN A 1 179  ? 159.849 130.087 176.961 1.00 62.62  ? 301  GLN A C   1 
ATOM   778  O O   . GLN A 1 179  ? 159.745 129.176 176.138 1.00 65.80  ? 301  GLN A O   1 
ATOM   779  C CB  . GLN A 1 179  ? 158.523 129.341 178.929 1.00 63.27  ? 301  GLN A CB  1 
ATOM   780  C CG  . GLN A 1 179  ? 158.495 128.710 180.303 1.00 69.11  ? 301  GLN A CG  1 
ATOM   781  C CD  . GLN A 1 179  ? 159.261 127.412 180.357 1.00 79.96  ? 301  GLN A CD  1 
ATOM   782  O OE1 . GLN A 1 179  ? 160.329 127.333 180.963 1.00 86.16  ? 301  GLN A OE1 1 
ATOM   783  N NE2 . GLN A 1 179  ? 158.718 126.379 179.729 1.00 83.49  ? 301  GLN A NE2 1 
ATOM   784  N N   . ARG A 1 180  ? 159.885 131.371 176.600 1.00 63.53  ? 302  ARG A N   1 
ATOM   785  C CA  . ARG A 1 180  ? 160.003 131.739 175.194 1.00 61.22  ? 302  ARG A CA  1 
ATOM   786  C C   . ARG A 1 180  ? 161.409 131.482 174.674 1.00 61.72  ? 302  ARG A C   1 
ATOM   787  O O   . ARG A 1 180  ? 161.576 130.956 173.571 1.00 67.38  ? 302  ARG A O   1 
ATOM   788  C CB  . ARG A 1 180  ? 159.619 133.203 174.995 1.00 66.33  ? 302  ARG A CB  1 
ATOM   789  C CG  . ARG A 1 180  ? 159.556 133.636 173.546 1.00 66.60  ? 302  ARG A CG  1 
ATOM   790  C CD  . ARG A 1 180  ? 160.056 135.055 173.386 1.00 73.28  ? 302  ARG A CD  1 
ATOM   791  N NE  . ARG A 1 180  ? 159.739 135.599 172.073 1.00 85.64  ? 302  ARG A NE  1 
ATOM   792  C CZ  . ARG A 1 180  ? 160.525 135.492 171.011 1.00 90.52  ? 302  ARG A CZ  1 
ATOM   793  N NH1 . ARG A 1 180  ? 161.691 134.870 171.075 1.00 85.23  ? 302  ARG A NH1 1 
ATOM   794  N NH2 . ARG A 1 180  ? 160.134 136.021 169.856 1.00 92.42  ? 302  ARG A NH2 1 
ATOM   795  N N   . LEU A 1 181  ? 162.437 131.816 175.465 1.00 64.36  ? 303  LEU A N   1 
ATOM   796  C CA  . LEU A 1 181  ? 163.802 131.544 175.008 1.00 65.72  ? 303  LEU A CA  1 
ATOM   797  C C   . LEU A 1 181  ? 164.201 130.081 175.192 1.00 67.13  ? 303  LEU A C   1 
ATOM   798  O O   . LEU A 1 181  ? 165.219 129.646 174.643 1.00 71.98  ? 303  LEU A O   1 
ATOM   799  C CB  . LEU A 1 181  ? 164.815 132.451 175.707 1.00 65.60  ? 303  LEU A CB  1 
ATOM   800  C CG  . LEU A 1 181  ? 164.568 133.953 175.798 1.00 70.29  ? 303  LEU A CG  1 
ATOM   801  C CD1 . LEU A 1 181  ? 165.723 134.629 176.511 1.00 70.19  ? 303  LEU A CD1 1 
ATOM   802  C CD2 . LEU A 1 181  ? 164.373 134.540 174.414 1.00 70.21  ? 303  LEU A CD2 1 
ATOM   803  N N   . ALA A 1 182  ? 163.432 129.308 175.964 1.00 66.70  ? 304  ALA A N   1 
ATOM   804  C CA  . ALA A 1 182  ? 163.796 127.912 176.198 1.00 65.57  ? 304  ALA A CA  1 
ATOM   805  C C   . ALA A 1 182  ? 163.461 127.017 175.008 1.00 69.04  ? 304  ALA A C   1 
ATOM   806  O O   . ALA A 1 182  ? 164.062 125.949 174.844 1.00 73.59  ? 304  ALA A O   1 
ATOM   807  C CB  . ALA A 1 182  ? 163.101 127.397 177.456 1.00 66.85  ? 304  ALA A CB  1 
ATOM   808  N N   . ILE A 1 183  ? 162.513 127.429 174.163 1.00 71.34  ? 305  ILE A N   1 
ATOM   809  C CA  . ILE A 1 183  ? 161.876 126.508 173.228 1.00 71.39  ? 305  ILE A CA  1 
ATOM   810  C C   . ILE A 1 183  ? 162.000 126.996 171.773 1.00 73.63  ? 305  ILE A C   1 
ATOM   811  O O   . ILE A 1 183  ? 161.668 126.247 170.842 1.00 81.06  ? 305  ILE A O   1 
ATOM   812  C CB  . ILE A 1 183  ? 160.403 126.312 173.682 1.00 68.47  ? 305  ILE A CB  1 
ATOM   813  C CG1 . ILE A 1 183  ? 159.726 125.026 173.175 1.00 75.02  ? 305  ILE A CG1 1 
ATOM   814  C CG2 . ILE A 1 183  ? 159.564 127.483 173.232 1.00 67.53  ? 305  ILE A CG2 1 
ATOM   815  C CD1 . ILE A 1 183  ? 160.333 123.764 173.730 1.00 83.24  ? 305  ILE A CD1 1 
ATOM   816  N N   . SER A 1 184  ? 162.592 128.184 171.560 1.00 70.05  ? 306  SER A N   1 
ATOM   817  C CA  . SER A 1 184  ? 162.441 128.938 170.310 1.00 70.69  ? 306  SER A CA  1 
ATOM   818  C C   . SER A 1 184  ? 163.219 128.337 169.143 1.00 78.46  ? 306  SER A C   1 
ATOM   819  O O   . SER A 1 184  ? 162.829 128.507 167.980 1.00 81.63  ? 306  SER A O   1 
ATOM   820  C CB  . SER A 1 184  ? 162.877 130.384 170.522 1.00 71.25  ? 306  SER A CB  1 
ATOM   821  O OG  . SER A 1 184  ? 162.835 131.105 169.306 1.00 76.39  ? 306  SER A OG  1 
ATOM   822  N N   . HIS A 1 185  ? 164.297 127.602 169.436 1.00 81.16  ? 307  HIS A N   1 
ATOM   823  C CA  . HIS A 1 185  ? 165.008 126.879 168.385 1.00 82.64  ? 307  HIS A CA  1 
ATOM   824  C C   . HIS A 1 185  ? 164.201 125.676 167.913 1.00 81.89  ? 307  HIS A C   1 
ATOM   825  O O   . HIS A 1 185  ? 164.115 125.402 166.711 1.00 85.29  ? 307  HIS A O   1 
ATOM   826  C CB  . HIS A 1 185  ? 166.394 126.453 168.881 1.00 85.32  ? 307  HIS A CB  1 
ATOM   827  C CG  . HIS A 1 185  ? 166.387 125.782 170.222 1.00 87.74  ? 307  HIS A CG  1 
ATOM   828  N ND1 . HIS A 1 185  ? 166.195 124.426 170.373 1.00 90.45  ? 307  HIS A ND1 1 
ATOM   829  C CD2 . HIS A 1 185  ? 166.526 126.283 171.472 1.00 85.25  ? 307  HIS A CD2 1 
ATOM   830  C CE1 . HIS A 1 185  ? 166.227 124.117 171.657 1.00 91.97  ? 307  HIS A CE1 1 
ATOM   831  N NE2 . HIS A 1 185  ? 166.426 125.228 172.346 1.00 90.16  ? 307  HIS A NE2 1 
ATOM   832  N N   . LEU A 1 186  ? 163.545 124.985 168.848 1.00 80.51  ? 308  LEU A N   1 
ATOM   833  C CA  . LEU A 1 186  ? 162.776 123.799 168.495 1.00 81.55  ? 308  LEU A CA  1 
ATOM   834  C C   . LEU A 1 186  ? 161.405 124.196 167.951 1.00 79.90  ? 308  LEU A C   1 
ATOM   835  O O   . LEU A 1 186  ? 160.760 123.420 167.239 1.00 81.51  ? 308  LEU A O   1 
ATOM   836  C CB  . LEU A 1 186  ? 162.691 122.881 169.720 1.00 84.85  ? 308  LEU A CB  1 
ATOM   837  C CG  . LEU A 1 186  ? 161.860 121.606 169.851 1.00 90.51  ? 308  LEU A CG  1 
ATOM   838  C CD1 . LEU A 1 186  ? 162.381 120.537 168.903 1.00 88.33  ? 308  LEU A CD1 1 
ATOM   839  C CD2 . LEU A 1 186  ? 161.878 121.110 171.283 1.00 92.97  ? 308  LEU A CD2 1 
ATOM   840  N N   . VAL A 1 187  ? 160.950 125.413 168.265 1.00 80.25  ? 309  VAL A N   1 
ATOM   841  C CA  . VAL A 1 187  ? 159.767 125.955 167.599 1.00 75.80  ? 309  VAL A CA  1 
ATOM   842  C C   . VAL A 1 187  ? 160.094 126.334 166.162 1.00 77.35  ? 309  VAL A C   1 
ATOM   843  O O   . VAL A 1 187  ? 159.434 125.873 165.225 1.00 83.97  ? 309  VAL A O   1 
ATOM   844  C CB  . VAL A 1 187  ? 159.191 127.144 168.394 1.00 78.73  ? 309  VAL A CB  1 
ATOM   845  C CG1 . VAL A 1 187  ? 158.154 127.906 167.584 1.00 79.46  ? 309  VAL A CG1 1 
ATOM   846  C CG2 . VAL A 1 187  ? 158.534 126.646 169.656 1.00 78.85  ? 309  VAL A CG2 1 
ATOM   847  N N   . GLU A 1 188  ? 161.149 127.123 165.953 1.00 78.56  ? 310  GLU A N   1 
ATOM   848  C CA  . GLU A 1 188  ? 161.424 127.659 164.624 1.00 81.60  ? 310  GLU A CA  1 
ATOM   849  C C   . GLU A 1 188  ? 162.283 126.747 163.753 1.00 81.28  ? 310  GLU A C   1 
ATOM   850  O O   . GLU A 1 188  ? 162.688 127.169 162.665 1.00 79.80  ? 310  GLU A O   1 
ATOM   851  C CB  . GLU A 1 188  ? 162.103 129.029 164.720 1.00 81.41  ? 310  GLU A CB  1 
ATOM   852  C CG  . GLU A 1 188  ? 161.147 130.190 164.908 1.00 84.42  ? 310  GLU A CG  1 
ATOM   853  C CD  . GLU A 1 188  ? 161.698 131.258 165.828 1.00 91.81  ? 310  GLU A CD  1 
ATOM   854  O OE1 . GLU A 1 188  ? 162.773 131.041 166.423 1.00 91.49  ? 310  GLU A OE1 1 
ATOM   855  O OE2 . GLU A 1 188  ? 161.059 132.324 165.951 1.00 93.39  ? 310  GLU A OE2 1 
ATOM   856  N N   . ARG A 1 189  ? 162.605 125.532 164.200 1.00 80.61  ? 311  ARG A N   1 
ATOM   857  C CA  . ARG A 1 189  ? 163.349 124.606 163.357 1.00 78.71  ? 311  ARG A CA  1 
ATOM   858  C C   . ARG A 1 189  ? 162.530 123.417 162.865 1.00 81.92  ? 311  ARG A C   1 
ATOM   859  O O   . ARG A 1 189  ? 162.876 122.843 161.831 1.00 87.14  ? 311  ARG A O   1 
ATOM   860  C CB  . ARG A 1 189  ? 164.622 124.129 164.091 1.00 81.73  ? 311  ARG A CB  1 
ATOM   861  C CG  . ARG A 1 189  ? 164.604 122.729 164.694 1.00 85.32  ? 311  ARG A CG  1 
ATOM   862  C CD  . ARG A 1 189  ? 165.766 122.445 165.605 1.00 91.25  ? 311  ARG A CD  1 
ATOM   863  N NE  . ARG A 1 189  ? 165.578 121.147 166.237 1.00 99.87  ? 311  ARG A NE  1 
ATOM   864  C CZ  . ARG A 1 189  ? 166.317 120.679 167.232 1.00 104.32 ? 311  ARG A CZ  1 
ATOM   865  N NH1 . ARG A 1 189  ? 167.305 121.388 167.750 1.00 103.58 ? 311  ARG A NH1 1 
ATOM   866  N NH2 . ARG A 1 189  ? 166.052 119.472 167.725 1.00 106.00 ? 311  ARG A NH2 1 
ATOM   867  N N   . THR A 1 190  ? 161.430 123.054 163.531 1.00 81.38  ? 312  THR A N   1 
ATOM   868  C CA  . THR A 1 190  ? 160.641 121.915 163.079 1.00 81.26  ? 312  THR A CA  1 
ATOM   869  C C   . THR A 1 190  ? 159.407 122.391 162.334 1.00 81.60  ? 312  THR A C   1 
ATOM   870  O O   . THR A 1 190  ? 158.709 123.309 162.774 1.00 80.20  ? 312  THR A O   1 
ATOM   871  C CB  . THR A 1 190  ? 160.233 121.010 164.235 1.00 81.81  ? 312  THR A CB  1 
ATOM   872  O OG1 . THR A 1 190  ? 159.092 121.573 164.884 1.00 81.63  ? 312  THR A OG1 1 
ATOM   873  C CG2 . THR A 1 190  ? 161.376 120.811 165.209 1.00 87.32  ? 312  THR A CG2 1 
ATOM   874  N N   . GLN A 1 191  ? 159.131 121.736 161.221 1.00 82.88  ? 313  GLN A N   1 
ATOM   875  C CA  . GLN A 1 191  ? 158.321 122.264 160.151 1.00 81.23  ? 313  GLN A CA  1 
ATOM   876  C C   . GLN A 1 191  ? 157.042 121.445 160.009 1.00 78.23  ? 313  GLN A C   1 
ATOM   877  O O   . GLN A 1 191  ? 157.113 120.209 160.018 1.00 78.05  ? 313  GLN A O   1 
ATOM   878  C CB  . GLN A 1 191  ? 159.182 122.240 158.870 1.00 81.19  ? 313  GLN A CB  1 
ATOM   879  C CG  . GLN A 1 191  ? 158.684 122.905 157.613 1.00 79.02  ? 313  GLN A CG  1 
ATOM   880  C CD  . GLN A 1 191  ? 157.819 122.024 156.772 1.00 83.29  ? 313  GLN A CD  1 
ATOM   881  O OE1 . GLN A 1 191  ? 157.970 120.802 156.764 1.00 85.70  ? 313  GLN A OE1 1 
ATOM   882  N NE2 . GLN A 1 191  ? 156.884 122.630 156.081 1.00 84.09  ? 313  GLN A NE2 1 
ATOM   883  N N   . PRO A 1 192  ? 155.863 122.081 159.924 1.00 75.25  ? 314  PRO A N   1 
ATOM   884  C CA  . PRO A 1 192  ? 154.610 121.312 159.842 1.00 76.69  ? 314  PRO A CA  1 
ATOM   885  C C   . PRO A 1 192  ? 154.380 120.692 158.472 1.00 81.90  ? 314  PRO A C   1 
ATOM   886  O O   . PRO A 1 192  ? 154.804 121.227 157.446 1.00 84.94  ? 314  PRO A O   1 
ATOM   887  C CB  . PRO A 1 192  ? 153.531 122.355 160.154 1.00 75.13  ? 314  PRO A CB  1 
ATOM   888  C CG  . PRO A 1 192  ? 154.155 123.655 159.866 1.00 70.78  ? 314  PRO A CG  1 
ATOM   889  C CD  . PRO A 1 192  ? 155.604 123.512 160.150 1.00 74.44  ? 314  PRO A CD  1 
ATOM   890  N N   . GLN A 1 193  ? 153.650 119.579 158.464 1.00 82.62  ? 315  GLN A N   1 
ATOM   891  C CA  . GLN A 1 193  ? 153.396 118.805 157.257 1.00 84.60  ? 315  GLN A CA  1 
ATOM   892  C C   . GLN A 1 193  ? 151.895 118.659 157.064 1.00 86.29  ? 315  GLN A C   1 
ATOM   893  O O   . GLN A 1 193  ? 151.164 118.423 158.031 1.00 87.75  ? 315  GLN A O   1 
ATOM   894  C CB  . GLN A 1 193  ? 154.039 117.422 157.342 1.00 88.34  ? 315  GLN A CB  1 
ATOM   895  C CG  . GLN A 1 193  ? 155.550 117.412 157.237 1.00 92.81  ? 315  GLN A CG  1 
ATOM   896  C CD  . GLN A 1 193  ? 156.163 116.286 158.043 1.00 103.30 ? 315  GLN A CD  1 
ATOM   897  O OE1 . GLN A 1 193  ? 155.459 115.566 158.751 1.00 106.18 ? 315  GLN A OE1 1 
ATOM   898  N NE2 . GLN A 1 193  ? 157.477 116.127 157.943 1.00 105.84 ? 315  GLN A NE2 1 
ATOM   899  N N   . LEU A 1 194  ? 151.441 118.782 155.819 1.00 84.42  ? 316  LEU A N   1 
ATOM   900  C CA  . LEU A 1 194  ? 150.033 118.591 155.492 1.00 82.23  ? 316  LEU A CA  1 
ATOM   901  C C   . LEU A 1 194  ? 149.827 117.164 155.004 1.00 88.59  ? 316  LEU A C   1 
ATOM   902  O O   . LEU A 1 194  ? 150.582 116.679 154.157 1.00 95.88  ? 316  LEU A O   1 
ATOM   903  C CB  . LEU A 1 194  ? 149.573 119.566 154.417 1.00 78.06  ? 316  LEU A CB  1 
ATOM   904  C CG  . LEU A 1 194  ? 149.201 120.983 154.823 1.00 76.47  ? 316  LEU A CG  1 
ATOM   905  C CD1 . LEU A 1 194  ? 149.217 121.834 153.586 1.00 74.49  ? 316  LEU A CD1 1 
ATOM   906  C CD2 . LEU A 1 194  ? 147.863 121.022 155.497 1.00 82.19  ? 316  LEU A CD2 1 
ATOM   907  N N   . GLU A 1 195  ? 148.805 116.496 155.533 1.00 90.20  ? 317  GLU A N   1 
ATOM   908  C CA  . GLU A 1 195  ? 148.432 115.155 155.103 1.00 95.88  ? 317  GLU A CA  1 
ATOM   909  C C   . GLU A 1 195  ? 146.956 115.143 154.739 1.00 98.89  ? 317  GLU A C   1 
ATOM   910  O O   . GLU A 1 195  ? 146.158 115.860 155.350 1.00 96.86  ? 317  GLU A O   1 
ATOM   911  C CB  . GLU A 1 195  ? 148.721 114.119 156.194 1.00 98.53  ? 317  GLU A CB  1 
ATOM   912  C CG  . GLU A 1 195  ? 150.201 113.916 156.479 1.00 101.94 ? 317  GLU A CG  1 
ATOM   913  C CD  . GLU A 1 195  ? 150.458 112.905 157.572 1.00 108.02 ? 317  GLU A CD  1 
ATOM   914  O OE1 . GLU A 1 195  ? 149.482 112.448 158.203 1.00 110.10 ? 317  GLU A OE1 1 
ATOM   915  O OE2 . GLU A 1 195  ? 151.637 112.563 157.799 1.00 109.43 ? 317  GLU A OE2 1 
ATOM   916  N N   . ARG A 1 196  ? 146.599 114.340 153.743 1.00 103.68 ? 318  ARG A N   1 
ATOM   917  C CA  . ARG A 1 196  ? 145.211 114.239 153.303 1.00 104.46 ? 318  ARG A CA  1 
ATOM   918  C C   . ARG A 1 196  ? 144.893 112.839 152.787 1.00 104.48 ? 318  ARG A C   1 
ATOM   919  O O   . ARG A 1 196  ? 145.751 112.167 152.215 1.00 105.91 ? 318  ARG A O   1 
ATOM   920  C CB  . ARG A 1 196  ? 144.915 115.275 152.218 1.00 102.16 ? 318  ARG A CB  1 
ATOM   921  C CG  . ARG A 1 196  ? 143.443 115.393 151.873 1.00 105.50 ? 318  ARG A CG  1 
ATOM   922  C CD  . ARG A 1 196  ? 143.212 116.355 150.723 1.00 109.28 ? 318  ARG A CD  1 
ATOM   923  N NE  . ARG A 1 196  ? 141.799 116.443 150.377 1.00 112.97 ? 318  ARG A NE  1 
ATOM   924  C CZ  . ARG A 1 196  ? 140.989 117.414 150.775 1.00 109.80 ? 318  ARG A CZ  1 
ATOM   925  N NH1 . ARG A 1 196  ? 141.427 118.419 151.515 1.00 100.97 ? 318  ARG A NH1 1 
ATOM   926  N NH2 . ARG A 1 196  ? 139.707 117.377 150.421 1.00 110.32 ? 318  ARG A NH2 1 
ATOM   927  N N   . THR A 1 205  ? 137.286 114.252 152.476 1.00 109.33 ? 327  THR A N   1 
ATOM   928  C CA  . THR A 1 205  ? 138.117 114.295 153.674 1.00 111.35 ? 327  THR A CA  1 
ATOM   929  C C   . THR A 1 205  ? 138.558 115.729 153.981 1.00 111.44 ? 327  THR A C   1 
ATOM   930  O O   . THR A 1 205  ? 138.932 116.463 153.067 1.00 110.87 ? 327  THR A O   1 
ATOM   931  C CB  . THR A 1 205  ? 139.363 113.405 153.533 1.00 111.68 ? 327  THR A CB  1 
ATOM   932  O OG1 . THR A 1 205  ? 140.260 113.985 152.577 1.00 113.17 ? 327  THR A OG1 1 
ATOM   933  C CG2 . THR A 1 205  ? 138.972 112.011 153.071 1.00 107.06 ? 327  THR A CG2 1 
ATOM   934  N N   . PRO A 1 206  ? 138.505 116.136 155.251 1.00 110.37 ? 328  PRO A N   1 
ATOM   935  C CA  . PRO A 1 206  ? 138.995 117.470 155.608 1.00 107.07 ? 328  PRO A CA  1 
ATOM   936  C C   . PRO A 1 206  ? 140.514 117.535 155.636 1.00 104.53 ? 328  PRO A C   1 
ATOM   937  O O   . PRO A 1 206  ? 141.209 116.519 155.700 1.00 102.50 ? 328  PRO A O   1 
ATOM   938  C CB  . PRO A 1 206  ? 138.407 117.704 157.003 1.00 102.97 ? 328  PRO A CB  1 
ATOM   939  C CG  . PRO A 1 206  ? 138.231 116.358 157.559 1.00 105.86 ? 328  PRO A CG  1 
ATOM   940  C CD  . PRO A 1 206  ? 137.913 115.448 156.415 1.00 108.60 ? 328  PRO A CD  1 
ATOM   941  N N   . LEU A 1 207  ? 141.017 118.764 155.579 1.00 101.54 ? 329  LEU A N   1 
ATOM   942  C CA  . LEU A 1 207  ? 142.450 119.012 155.536 1.00 96.90  ? 329  LEU A CA  1 
ATOM   943  C C   . LEU A 1 207  ? 143.060 118.854 156.922 1.00 97.09  ? 329  LEU A C   1 
ATOM   944  O O   . LEU A 1 207  ? 142.496 119.312 157.919 1.00 98.63  ? 329  LEU A O   1 
ATOM   945  C CB  . LEU A 1 207  ? 142.714 120.414 154.992 1.00 92.73  ? 329  LEU A CB  1 
ATOM   946  C CG  . LEU A 1 207  ? 144.152 120.804 154.686 1.00 85.83  ? 329  LEU A CG  1 
ATOM   947  C CD1 . LEU A 1 207  ? 144.728 119.870 153.643 1.00 89.14  ? 329  LEU A CD1 1 
ATOM   948  C CD2 . LEU A 1 207  ? 144.225 122.244 154.221 1.00 81.57  ? 329  LEU A CD2 1 
ATOM   949  N N   . THR A 1 208  ? 144.220 118.201 156.982 1.00 95.26  ? 330  THR A N   1 
ATOM   950  C CA  . THR A 1 208  ? 144.852 117.834 158.243 1.00 90.99  ? 330  THR A CA  1 
ATOM   951  C C   . THR A 1 208  ? 146.289 118.337 158.263 1.00 88.86  ? 330  THR A C   1 
ATOM   952  O O   . THR A 1 208  ? 147.067 118.022 157.358 1.00 92.13  ? 330  THR A O   1 
ATOM   953  C CB  . THR A 1 208  ? 144.807 116.317 158.442 1.00 90.85  ? 330  THR A CB  1 
ATOM   954  O OG1 . THR A 1 208  ? 143.448 115.868 158.388 1.00 94.71  ? 330  THR A OG1 1 
ATOM   955  C CG2 . THR A 1 208  ? 145.396 115.928 159.771 1.00 88.85  ? 330  THR A CG2 1 
ATOM   956  N N   . ILE A 1 209  ? 146.641 119.111 159.293 1.00 82.21  ? 331  ILE A N   1 
ATOM   957  C CA  . ILE A 1 209  ? 148.015 119.557 159.519 1.00 80.75  ? 331  ILE A CA  1 
ATOM   958  C C   . ILE A 1 209  ? 148.635 118.690 160.604 1.00 85.61  ? 331  ILE A C   1 
ATOM   959  O O   . ILE A 1 209  ? 148.031 118.478 161.662 1.00 91.04  ? 331  ILE A O   1 
ATOM   960  C CB  . ILE A 1 209  ? 148.075 121.039 159.921 1.00 74.81  ? 331  ILE A CB  1 
ATOM   961  C CG1 . ILE A 1 209  ? 147.090 121.866 159.106 1.00 76.86  ? 331  ILE A CG1 1 
ATOM   962  C CG2 . ILE A 1 209  ? 149.487 121.582 159.745 1.00 75.24  ? 331  ILE A CG2 1 
ATOM   963  C CD1 . ILE A 1 209  ? 147.019 123.306 159.541 1.00 75.98  ? 331  ILE A CD1 1 
ATOM   964  N N   . ARG A 1 210  ? 149.841 118.193 160.348 1.00 84.29  ? 332  ARG A N   1 
ATOM   965  C CA  . ARG A 1 210  ? 150.616 117.451 161.332 1.00 84.40  ? 332  ARG A CA  1 
ATOM   966  C C   . ARG A 1 210  ? 151.838 118.282 161.690 1.00 84.74  ? 332  ARG A C   1 
ATOM   967  O O   . ARG A 1 210  ? 152.545 118.762 160.799 1.00 86.18  ? 332  ARG A O   1 
ATOM   968  C CB  . ARG A 1 210  ? 151.025 116.082 160.791 1.00 89.78  ? 332  ARG A CB  1 
ATOM   969  C CG  . ARG A 1 210  ? 151.660 115.165 161.817 1.00 93.27  ? 332  ARG A CG  1 
ATOM   970  C CD  . ARG A 1 210  ? 151.877 113.788 161.222 1.00 101.15 ? 332  ARG A CD  1 
ATOM   971  N NE  . ARG A 1 210  ? 150.613 113.161 160.852 1.00 105.73 ? 332  ARG A NE  1 
ATOM   972  C CZ  . ARG A 1 210  ? 149.911 112.361 161.642 1.00 107.18 ? 332  ARG A CZ  1 
ATOM   973  N NH1 . ARG A 1 210  ? 150.343 112.026 162.846 1.00 108.92 ? 332  ARG A NH1 1 
ATOM   974  N NH2 . ARG A 1 210  ? 148.751 111.879 161.208 1.00 105.13 ? 332  ARG A NH2 1 
ATOM   975  N N   . TRP A 1 211  ? 152.073 118.462 162.986 1.00 86.41  ? 333  TRP A N   1 
ATOM   976  C CA  . TRP A 1 211  ? 153.151 119.300 163.500 1.00 82.70  ? 333  TRP A CA  1 
ATOM   977  C C   . TRP A 1 211  ? 153.827 118.567 164.644 1.00 84.77  ? 333  TRP A C   1 
ATOM   978  O O   . TRP A 1 211  ? 153.437 118.725 165.806 1.00 87.09  ? 333  TRP A O   1 
ATOM   979  C CB  . TRP A 1 211  ? 152.592 120.653 163.932 1.00 81.13  ? 333  TRP A CB  1 
ATOM   980  C CG  . TRP A 1 211  ? 153.566 121.720 164.308 1.00 80.05  ? 333  TRP A CG  1 
ATOM   981  C CD1 . TRP A 1 211  ? 154.578 122.208 163.546 1.00 80.93  ? 333  TRP A CD1 1 
ATOM   982  C CD2 . TRP A 1 211  ? 153.478 122.584 165.445 1.00 83.02  ? 333  TRP A CD2 1 
ATOM   983  N NE1 . TRP A 1 211  ? 155.198 123.250 164.182 1.00 76.48  ? 333  TRP A NE1 1 
ATOM   984  C CE2 . TRP A 1 211  ? 154.534 123.511 165.348 1.00 77.89  ? 333  TRP A CE2 1 
ATOM   985  C CE3 . TRP A 1 211  ? 152.631 122.636 166.561 1.00 87.74  ? 333  TRP A CE3 1 
ATOM   986  C CZ2 . TRP A 1 211  ? 154.767 124.481 166.317 1.00 78.24  ? 333  TRP A CZ2 1 
ATOM   987  C CZ3 . TRP A 1 211  ? 152.869 123.600 167.531 1.00 86.81  ? 333  TRP A CZ3 1 
ATOM   988  C CH2 . TRP A 1 211  ? 153.933 124.505 167.402 1.00 81.62  ? 333  TRP A CH2 1 
ATOM   989  N N   . ALA A 1 212  ? 154.846 117.777 164.313 1.00 88.04  ? 334  ALA A N   1 
ATOM   990  C CA  . ALA A 1 212  ? 155.455 116.849 165.260 1.00 92.81  ? 334  ALA A CA  1 
ATOM   991  C C   . ALA A 1 212  ? 156.452 117.576 166.165 1.00 97.14  ? 334  ALA A C   1 
ATOM   992  O O   . ALA A 1 212  ? 157.659 117.604 165.930 1.00 99.29  ? 334  ALA A O   1 
ATOM   993  C CB  . ALA A 1 212  ? 156.122 115.701 164.514 1.00 90.97  ? 334  ALA A CB  1 
ATOM   994  N N   . MET A 1 213  ? 155.911 118.184 167.217 1.00 100.53 ? 335  MET A N   1 
ATOM   995  C CA  . MET A 1 213  ? 156.717 118.822 168.255 1.00 104.30 ? 335  MET A CA  1 
ATOM   996  C C   . MET A 1 213  ? 156.539 118.066 169.561 1.00 111.08 ? 335  MET A C   1 
ATOM   997  O O   . MET A 1 213  ? 155.417 117.761 169.972 1.00 110.77 ? 335  MET A O   1 
ATOM   998  C CB  . MET A 1 213  ? 156.353 120.287 168.438 1.00 96.53  ? 335  MET A CB  1 
ATOM   999  C CG  . MET A 1 213  ? 157.109 121.200 167.537 1.00 92.20  ? 335  MET A CG  1 
ATOM   1000 S SD  . MET A 1 213  ? 157.280 122.820 168.274 1.00 97.06  ? 335  MET A SD  1 
ATOM   1001 C CE  . MET A 1 213  ? 158.152 122.388 169.764 1.00 96.91  ? 335  MET A CE  1 
ATOM   1002 N N   . HIS A 1 214  ? 157.661 117.772 170.218 1.00 116.19 ? 336  HIS A N   1 
ATOM   1003 C CA  . HIS A 1 214  ? 157.657 117.160 171.544 1.00 119.67 ? 336  HIS A CA  1 
ATOM   1004 C C   . HIS A 1 214  ? 157.909 118.251 172.579 1.00 118.54 ? 336  HIS A C   1 
ATOM   1005 O O   . HIS A 1 214  ? 159.022 118.754 172.748 1.00 118.83 ? 336  HIS A O   1 
ATOM   1006 C CB  . HIS A 1 214  ? 158.698 116.054 171.637 1.00 120.02 ? 336  HIS A CB  1 
ATOM   1007 C CG  . HIS A 1 214  ? 158.881 115.288 170.365 1.00 121.06 ? 336  HIS A CG  1 
ATOM   1008 N ND1 . HIS A 1 214  ? 159.986 115.444 169.555 1.00 120.42 ? 336  HIS A ND1 1 
ATOM   1009 C CD2 . HIS A 1 214  ? 158.091 114.377 169.752 1.00 120.97 ? 336  HIS A CD2 1 
ATOM   1010 C CE1 . HIS A 1 214  ? 159.876 114.650 168.507 1.00 121.65 ? 336  HIS A CE1 1 
ATOM   1011 N NE2 . HIS A 1 214  ? 158.734 113.994 168.599 1.00 121.14 ? 336  HIS A NE2 1 
ATOM   1012 N N   . PHE A 1 215  ? 156.813 118.815 173.090 1.00 116.67 ? 337  PHE A N   1 
ATOM   1013 C CA  . PHE A 1 215  ? 156.954 119.957 174.028 1.00 118.99 ? 337  PHE A CA  1 
ATOM   1014 C C   . PHE A 1 215  ? 157.426 119.421 175.374 1.00 123.79 ? 337  PHE A C   1 
ATOM   1015 O O   . PHE A 1 215  ? 157.146 118.248 175.676 1.00 122.81 ? 337  PHE A O   1 
ATOM   1016 C CB  . PHE A 1 215  ? 155.621 120.687 174.196 1.00 117.95 ? 337  PHE A CB  1 
ATOM   1017 C CG  . PHE A 1 215  ? 155.412 121.881 173.301 1.00 116.17 ? 337  PHE A CG  1 
ATOM   1018 C CD1 . PHE A 1 215  ? 155.916 123.124 173.648 1.00 113.30 ? 337  PHE A CD1 1 
ATOM   1019 C CD2 . PHE A 1 215  ? 154.693 121.770 172.123 1.00 113.17 ? 337  PHE A CD2 1 
ATOM   1020 C CE1 . PHE A 1 215  ? 155.717 124.224 172.829 1.00 112.05 ? 337  PHE A CE1 1 
ATOM   1021 C CE2 . PHE A 1 215  ? 154.493 122.870 171.305 1.00 110.26 ? 337  PHE A CE2 1 
ATOM   1022 C CZ  . PHE A 1 215  ? 155.006 124.094 171.660 1.00 110.06 ? 337  PHE A CZ  1 
ATOM   1023 N N   . PRO A 1 216  ? 158.127 120.220 176.205 1.00 124.86 ? 338  PRO A N   1 
ATOM   1024 C CA  . PRO A 1 216  ? 158.517 119.769 177.535 1.00 124.64 ? 338  PRO A CA  1 
ATOM   1025 C C   . PRO A 1 216  ? 157.260 119.585 178.394 1.00 125.26 ? 338  PRO A C   1 
ATOM   1026 O O   . PRO A 1 216  ? 156.297 120.292 178.174 1.00 123.24 ? 338  PRO A O   1 
ATOM   1027 C CB  . PRO A 1 216  ? 159.357 120.929 178.080 1.00 120.63 ? 338  PRO A CB  1 
ATOM   1028 C CG  . PRO A 1 216  ? 159.788 121.690 176.850 1.00 116.51 ? 338  PRO A CG  1 
ATOM   1029 C CD  . PRO A 1 216  ? 158.617 121.560 175.901 1.00 118.41 ? 338  PRO A CD  1 
ATOM   1030 N N   . GLU A 1 217  ? 157.304 118.658 179.352 1.00 126.61 ? 339  GLU A N   1 
ATOM   1031 C CA  . GLU A 1 217  ? 156.148 118.422 180.255 1.00 126.96 ? 339  GLU A CA  1 
ATOM   1032 C C   . GLU A 1 217  ? 155.909 119.707 181.051 1.00 127.71 ? 339  GLU A C   1 
ATOM   1033 O O   . GLU A 1 217  ? 154.770 119.914 181.512 1.00 128.26 ? 339  GLU A O   1 
ATOM   1034 C CB  . GLU A 1 217  ? 156.422 117.236 181.179 1.00 122.49 ? 339  GLU A CB  1 
ATOM   1035 N N   . HIS A 1 218  ? 156.944 120.537 181.190 1.00 126.15 ? 340  HIS A N   1 
ATOM   1036 C CA  . HIS A 1 218  ? 156.841 121.823 181.927 1.00 121.38 ? 340  HIS A CA  1 
ATOM   1037 C C   . HIS A 1 218  ? 155.837 122.763 181.250 1.00 119.89 ? 340  HIS A C   1 
ATOM   1038 O O   . HIS A 1 218  ? 155.433 123.716 181.930 1.00 120.15 ? 340  HIS A O   1 
ATOM   1039 C CB  . HIS A 1 218  ? 158.227 122.467 182.009 1.00 115.56 ? 340  HIS A CB  1 
ATOM   1040 N N   . TYR A 1 219  ? 155.544 122.574 179.959 1.00 116.48 ? 341  TYR A N   1 
ATOM   1041 C CA  . TYR A 1 219  ? 154.589 123.423 179.187 1.00 115.63 ? 341  TYR A CA  1 
ATOM   1042 C C   . TYR A 1 219  ? 155.166 124.829 178.977 1.00 114.31 ? 341  TYR A C   1 
ATOM   1043 O O   . TYR A 1 219  ? 155.412 125.170 177.803 1.00 109.25 ? 341  TYR A O   1 
ATOM   1044 C CB  . TYR A 1 219  ? 153.143 123.343 179.702 1.00 113.64 ? 341  TYR A CB  1 
ATOM   1045 C CG  . TYR A 1 219  ? 152.775 124.150 180.924 1.00 112.24 ? 341  TYR A CG  1 
ATOM   1046 C CD1 . TYR A 1 219  ? 152.744 125.535 180.899 1.00 107.08 ? 341  TYR A CD1 1 
ATOM   1047 C CD2 . TYR A 1 219  ? 152.412 123.522 182.104 1.00 109.81 ? 341  TYR A CD2 1 
ATOM   1048 C CE1 . TYR A 1 219  ? 152.405 126.273 182.021 1.00 104.67 ? 341  TYR A CE1 1 
ATOM   1049 C CE2 . TYR A 1 219  ? 152.070 124.243 183.235 1.00 108.11 ? 341  TYR A CE2 1 
ATOM   1050 C CZ  . TYR A 1 219  ? 152.063 125.624 183.193 1.00 106.03 ? 341  TYR A CZ  1 
ATOM   1051 O OH  . TYR A 1 219  ? 151.720 126.340 184.302 1.00 100.41 ? 341  TYR A OH  1 
ATOM   1052 N N   . PRO A 1 224  ? 147.206 127.729 174.111 1.00 69.76  ? 346  PRO A N   1 
ATOM   1053 C CA  . PRO A 1 224  ? 146.521 128.847 173.453 1.00 73.13  ? 346  PRO A CA  1 
ATOM   1054 C C   . PRO A 1 224  ? 147.078 129.118 172.062 1.00 74.93  ? 346  PRO A C   1 
ATOM   1055 O O   . PRO A 1 224  ? 147.316 130.268 171.706 1.00 78.89  ? 346  PRO A O   1 
ATOM   1056 C CB  . PRO A 1 224  ? 146.792 130.026 174.390 1.00 66.15  ? 346  PRO A CB  1 
ATOM   1057 C CG  . PRO A 1 224  ? 147.032 129.403 175.717 1.00 67.84  ? 346  PRO A CG  1 
ATOM   1058 C CD  . PRO A 1 224  ? 147.718 128.099 175.441 1.00 67.51  ? 346  PRO A CD  1 
ATOM   1059 N N   . PHE A 1 225  ? 147.279 128.053 171.295 1.00 65.31  ? 347  PHE A N   1 
ATOM   1060 C CA  . PHE A 1 225  ? 147.888 128.157 169.977 1.00 56.86  ? 347  PHE A CA  1 
ATOM   1061 C C   . PHE A 1 225  ? 146.890 128.680 168.949 1.00 55.58  ? 347  PHE A C   1 
ATOM   1062 O O   . PHE A 1 225  ? 145.678 128.482 169.066 1.00 62.65  ? 347  PHE A O   1 
ATOM   1063 C CB  . PHE A 1 225  ? 148.505 126.788 169.615 1.00 59.32  ? 347  PHE A CB  1 
ATOM   1064 C CG  . PHE A 1 225  ? 147.508 125.689 169.283 1.00 59.47  ? 347  PHE A CG  1 
ATOM   1065 C CD1 . PHE A 1 225  ? 147.193 124.762 170.275 1.00 61.18  ? 347  PHE A CD1 1 
ATOM   1066 C CD2 . PHE A 1 225  ? 147.083 125.425 167.963 1.00 55.85  ? 347  PHE A CD2 1 
ATOM   1067 C CE1 . PHE A 1 225  ? 146.317 123.709 170.023 1.00 63.39  ? 347  PHE A CE1 1 
ATOM   1068 C CE2 . PHE A 1 225  ? 146.211 124.373 167.697 1.00 59.59  ? 347  PHE A CE2 1 
ATOM   1069 C CZ  . PHE A 1 225  ? 145.841 123.510 168.733 1.00 64.88  ? 347  PHE A CZ  1 
ATOM   1070 N N   . ASN A 1 226  ? 147.418 129.344 167.926 1.00 50.88  ? 348  ASN A N   1 
ATOM   1071 C CA  . ASN A 1 226  ? 146.638 129.799 166.784 1.00 48.74  ? 348  ASN A CA  1 
ATOM   1072 C C   . ASN A 1 226  ? 147.223 129.200 165.515 1.00 51.54  ? 348  ASN A C   1 
ATOM   1073 O O   . ASN A 1 226  ? 148.444 129.150 165.355 1.00 58.09  ? 348  ASN A O   1 
ATOM   1074 C CB  . ASN A 1 226  ? 146.634 131.325 166.675 1.00 49.98  ? 348  ASN A CB  1 
ATOM   1075 C CG  . ASN A 1 226  ? 145.758 131.986 167.713 1.00 59.97  ? 348  ASN A CG  1 
ATOM   1076 O OD1 . ASN A 1 226  ? 145.044 131.318 168.459 1.00 68.19  ? 348  ASN A OD1 1 
ATOM   1077 N ND2 . ASN A 1 226  ? 145.804 133.310 167.765 1.00 58.45  ? 348  ASN A ND2 1 
ATOM   1078 N N   . ILE A 1 227  ? 146.356 128.749 164.626 1.00 44.67  ? 349  ILE A N   1 
ATOM   1079 C CA  . ILE A 1 227  ? 146.761 128.347 163.287 1.00 35.58  ? 349  ILE A CA  1 
ATOM   1080 C C   . ILE A 1 227  ? 146.469 129.502 162.346 1.00 36.29  ? 349  ILE A C   1 
ATOM   1081 O O   . ILE A 1 227  ? 145.378 130.076 162.367 1.00 45.97  ? 349  ILE A O   1 
ATOM   1082 C CB  . ILE A 1 227  ? 146.034 127.064 162.848 1.00 33.29  ? 349  ILE A CB  1 
ATOM   1083 C CG1 . ILE A 1 227  ? 146.065 126.034 163.978 1.00 41.63  ? 349  ILE A CG1 1 
ATOM   1084 C CG2 . ILE A 1 227  ? 146.667 126.504 161.589 1.00 30.71  ? 349  ILE A CG2 1 
ATOM   1085 C CD1 . ILE A 1 227  ? 145.393 124.714 163.653 1.00 43.34  ? 349  ILE A CD1 1 
ATOM   1086 N N   . GLN A 1 228  ? 147.454 129.866 161.537 1.00 34.39  ? 350  GLN A N   1 
ATOM   1087 C CA  . GLN A 1 228  ? 147.328 130.966 160.599 1.00 41.46  ? 350  GLN A CA  1 
ATOM   1088 C C   . GLN A 1 228  ? 147.379 130.430 159.176 1.00 42.40  ? 350  GLN A C   1 
ATOM   1089 O O   . GLN A 1 228  ? 147.859 129.323 158.930 1.00 51.46  ? 350  GLN A O   1 
ATOM   1090 C CB  . GLN A 1 228  ? 148.436 131.999 160.817 1.00 39.40  ? 350  GLN A CB  1 
ATOM   1091 C CG  . GLN A 1 228  ? 148.259 132.826 162.070 1.00 35.38  ? 350  GLN A CG  1 
ATOM   1092 C CD  . GLN A 1 228  ? 149.146 134.049 162.089 1.00 41.13  ? 350  GLN A CD  1 
ATOM   1093 O OE1 . GLN A 1 228  ? 150.190 134.082 161.444 1.00 48.12  ? 350  GLN A OE1 1 
ATOM   1094 N NE2 . GLN A 1 228  ? 148.725 135.070 162.821 1.00 36.91  ? 350  GLN A NE2 1 
ATOM   1095 N N   . TYR A 1 229  ? 146.861 131.215 158.235 1.00 40.18  ? 351  TYR A N   1 
ATOM   1096 C CA  . TYR A 1 229  ? 146.949 130.864 156.825 1.00 38.87  ? 351  TYR A CA  1 
ATOM   1097 C C   . TYR A 1 229  ? 147.367 132.086 156.026 1.00 43.65  ? 351  TYR A C   1 
ATOM   1098 O O   . TYR A 1 229  ? 147.119 133.224 156.427 1.00 50.58  ? 351  TYR A O   1 
ATOM   1099 C CB  . TYR A 1 229  ? 145.631 130.264 156.284 1.00 39.97  ? 351  TYR A CB  1 
ATOM   1100 C CG  . TYR A 1 229  ? 144.397 131.153 156.280 1.00 41.38  ? 351  TYR A CG  1 
ATOM   1101 C CD1 . TYR A 1 229  ? 143.550 131.186 157.391 1.00 42.89  ? 351  TYR A CD1 1 
ATOM   1102 C CD2 . TYR A 1 229  ? 144.036 131.896 155.145 1.00 41.45  ? 351  TYR A CD2 1 
ATOM   1103 C CE1 . TYR A 1 229  ? 142.402 131.977 157.397 1.00 45.61  ? 351  TYR A CE1 1 
ATOM   1104 C CE2 . TYR A 1 229  ? 142.894 132.694 155.140 1.00 42.95  ? 351  TYR A CE2 1 
ATOM   1105 C CZ  . TYR A 1 229  ? 142.085 132.722 156.267 1.00 42.20  ? 351  TYR A CZ  1 
ATOM   1106 O OH  . TYR A 1 229  ? 140.953 133.503 156.268 1.00 43.21  ? 351  TYR A OH  1 
ATOM   1107 N N   . GLN A 1 230  ? 148.014 131.837 154.895 1.00 45.31  ? 352  GLN A N   1 
ATOM   1108 C CA  . GLN A 1 230  ? 148.407 132.898 153.987 1.00 47.29  ? 352  GLN A CA  1 
ATOM   1109 C C   . GLN A 1 230  ? 148.164 132.451 152.556 1.00 56.67  ? 352  GLN A C   1 
ATOM   1110 O O   . GLN A 1 230  ? 148.444 131.303 152.199 1.00 62.74  ? 352  GLN A O   1 
ATOM   1111 C CB  . GLN A 1 230  ? 149.871 133.279 154.157 1.00 48.31  ? 352  GLN A CB  1 
ATOM   1112 C CG  . GLN A 1 230  ? 150.194 134.661 153.635 1.00 49.41  ? 352  GLN A CG  1 
ATOM   1113 C CD  . GLN A 1 230  ? 151.668 134.904 153.561 1.00 60.96  ? 352  GLN A CD  1 
ATOM   1114 O OE1 . GLN A 1 230  ? 152.449 133.970 153.621 1.00 58.02  ? 352  GLN A OE1 1 
ATOM   1115 N NE2 . GLN A 1 230  ? 152.061 136.163 153.437 1.00 65.92  ? 352  GLN A NE2 1 
ATOM   1116 N N   . PHE A 1 231  ? 147.642 133.366 151.743 1.00 53.43  ? 353  PHE A N   1 
ATOM   1117 C CA  . PHE A 1 231  ? 147.434 133.128 150.321 1.00 53.65  ? 353  PHE A CA  1 
ATOM   1118 C C   . PHE A 1 231  ? 148.775 133.241 149.606 1.00 63.39  ? 353  PHE A C   1 
ATOM   1119 O O   . PHE A 1 231  ? 149.445 134.276 149.687 1.00 67.74  ? 353  PHE A O   1 
ATOM   1120 C CB  . PHE A 1 231  ? 146.446 134.144 149.762 1.00 50.61  ? 353  PHE A CB  1 
ATOM   1121 C CG  . PHE A 1 231  ? 145.017 133.894 150.147 1.00 50.43  ? 353  PHE A CG  1 
ATOM   1122 C CD1 . PHE A 1 231  ? 144.231 132.999 149.419 1.00 52.98  ? 353  PHE A CD1 1 
ATOM   1123 C CD2 . PHE A 1 231  ? 144.461 134.558 151.239 1.00 49.07  ? 353  PHE A CD2 1 
ATOM   1124 C CE1 . PHE A 1 231  ? 142.899 132.779 149.767 1.00 50.34  ? 353  PHE A CE1 1 
ATOM   1125 C CE2 . PHE A 1 231  ? 143.136 134.340 151.607 1.00 44.79  ? 353  PHE A CE2 1 
ATOM   1126 C CZ  . PHE A 1 231  ? 142.358 133.446 150.870 1.00 44.39  ? 353  PHE A CZ  1 
ATOM   1127 N N   . VAL A 1 232  ? 149.172 132.183 148.898 1.00 64.13  ? 354  VAL A N   1 
ATOM   1128 C CA  . VAL A 1 232  ? 150.361 132.265 148.062 1.00 66.82  ? 354  VAL A CA  1 
ATOM   1129 C C   . VAL A 1 232  ? 149.985 132.898 146.731 1.00 74.66  ? 354  VAL A C   1 
ATOM   1130 O O   . VAL A 1 232  ? 149.004 132.490 146.093 1.00 76.69  ? 354  VAL A O   1 
ATOM   1131 C CB  . VAL A 1 232  ? 150.979 130.869 147.876 1.00 67.86  ? 354  VAL A CB  1 
ATOM   1132 C CG1 . VAL A 1 232  ? 152.341 130.949 147.212 1.00 76.28  ? 354  VAL A CG1 1 
ATOM   1133 C CG2 . VAL A 1 232  ? 151.064 130.149 149.205 1.00 63.41  ? 354  VAL A CG2 1 
ATOM   1134 N N   . ASP A 1 233  ? 150.783 133.898 146.317 1.00 76.37  ? 355  ASP A N   1 
ATOM   1135 C CA  . ASP A 1 233  ? 150.653 134.810 145.145 1.00 81.57  ? 355  ASP A CA  1 
ATOM   1136 C C   . ASP A 1 233  ? 149.246 135.341 144.836 1.00 80.73  ? 355  ASP A C   1 
ATOM   1137 O O   . ASP A 1 233  ? 148.572 135.869 145.717 1.00 72.06  ? 355  ASP A O   1 
ATOM   1138 C CB  . ASP A 1 233  ? 151.271 134.169 143.868 1.00 88.79  ? 355  ASP A CB  1 
ATOM   1139 C CG  . ASP A 1 233  ? 150.533 132.925 143.367 1.00 90.76  ? 355  ASP A CG  1 
ATOM   1140 O OD1 . ASP A 1 233  ? 149.497 133.047 142.675 1.00 89.62  ? 355  ASP A OD1 1 
ATOM   1141 O OD2 . ASP A 1 233  ? 150.997 131.809 143.678 1.00 90.34  ? 355  ASP A OD2 1 
ATOM   1142 N N   . SER A 1 255  ? 150.723 137.844 150.589 1.00 68.78  ? 377  SER A N   1 
ATOM   1143 C CA  . SER A 1 255  ? 149.741 138.640 151.315 1.00 74.84  ? 377  SER A CA  1 
ATOM   1144 C C   . SER A 1 255  ? 150.088 138.716 152.796 1.00 72.89  ? 377  SER A C   1 
ATOM   1145 O O   . SER A 1 255  ? 151.236 138.506 153.186 1.00 69.75  ? 377  SER A O   1 
ATOM   1146 C CB  . SER A 1 255  ? 148.339 138.053 151.139 1.00 75.10  ? 377  SER A CB  1 
ATOM   1147 O OG  . SER A 1 255  ? 148.230 136.801 151.791 1.00 74.38  ? 377  SER A OG  1 
ATOM   1148 N N   . ALA A 1 256  ? 149.089 139.026 153.615 1.00 71.69  ? 378  ALA A N   1 
ATOM   1149 C CA  . ALA A 1 256  ? 149.262 138.984 155.059 1.00 68.19  ? 378  ALA A CA  1 
ATOM   1150 C C   . ALA A 1 256  ? 148.776 137.649 155.602 1.00 66.31  ? 378  ALA A C   1 
ATOM   1151 O O   . ALA A 1 256  ? 148.023 136.930 154.941 1.00 66.65  ? 378  ALA A O   1 
ATOM   1152 C CB  . ALA A 1 256  ? 148.503 140.131 155.722 1.00 67.80  ? 378  ALA A CB  1 
ATOM   1153 N N   . TRP A 1 257  ? 149.214 137.314 156.811 1.00 60.82  ? 379  TRP A N   1 
ATOM   1154 C CA  . TRP A 1 257  ? 148.750 136.092 157.450 1.00 57.27  ? 379  TRP A CA  1 
ATOM   1155 C C   . TRP A 1 257  ? 147.429 136.337 158.163 1.00 60.97  ? 379  TRP A C   1 
ATOM   1156 O O   . TRP A 1 257  ? 147.294 137.279 158.947 1.00 62.97  ? 379  TRP A O   1 
ATOM   1157 C CB  . TRP A 1 257  ? 149.793 135.576 158.437 1.00 53.39  ? 379  TRP A CB  1 
ATOM   1158 C CG  . TRP A 1 257  ? 150.990 134.979 157.784 1.00 53.03  ? 379  TRP A CG  1 
ATOM   1159 C CD1 . TRP A 1 257  ? 152.096 135.639 157.346 1.00 52.95  ? 379  TRP A CD1 1 
ATOM   1160 C CD2 . TRP A 1 257  ? 151.204 133.596 157.491 1.00 49.11  ? 379  TRP A CD2 1 
ATOM   1161 N NE1 . TRP A 1 257  ? 152.990 134.754 156.800 1.00 49.69  ? 379  TRP A NE1 1 
ATOM   1162 C CE2 . TRP A 1 257  ? 152.465 133.492 156.873 1.00 48.74  ? 379  TRP A CE2 1 
ATOM   1163 C CE3 . TRP A 1 257  ? 150.451 132.434 157.690 1.00 47.66  ? 379  TRP A CE3 1 
ATOM   1164 C CZ2 . TRP A 1 257  ? 152.992 132.272 156.453 1.00 48.90  ? 379  TRP A CZ2 1 
ATOM   1165 C CZ3 . TRP A 1 257  ? 150.973 131.222 157.267 1.00 44.30  ? 379  TRP A CZ3 1 
ATOM   1166 C CH2 . TRP A 1 257  ? 152.232 131.151 156.660 1.00 45.44  ? 379  TRP A CH2 1 
ATOM   1167 N N   . PHE A 1 258  ? 146.453 135.482 157.887 1.00 62.96  ? 380  PHE A N   1 
ATOM   1168 C CA  . PHE A 1 258  ? 145.123 135.593 158.460 1.00 59.42  ? 380  PHE A CA  1 
ATOM   1169 C C   . PHE A 1 258  ? 144.908 134.467 159.456 1.00 55.89  ? 380  PHE A C   1 
ATOM   1170 O O   . PHE A 1 258  ? 145.349 133.339 159.236 1.00 60.72  ? 380  PHE A O   1 
ATOM   1171 C CB  . PHE A 1 258  ? 144.034 135.531 157.382 1.00 60.50  ? 380  PHE A CB  1 
ATOM   1172 C CG  . PHE A 1 258  ? 144.129 136.620 156.356 1.00 61.46  ? 380  PHE A CG  1 
ATOM   1173 C CD1 . PHE A 1 258  ? 143.554 137.866 156.599 1.00 63.75  ? 380  PHE A CD1 1 
ATOM   1174 C CD2 . PHE A 1 258  ? 144.770 136.388 155.137 1.00 62.61  ? 380  PHE A CD2 1 
ATOM   1175 C CE1 . PHE A 1 258  ? 143.633 138.883 155.648 1.00 66.18  ? 380  PHE A CE1 1 
ATOM   1176 C CE2 . PHE A 1 258  ? 144.856 137.394 154.177 1.00 66.13  ? 380  PHE A CE2 1 
ATOM   1177 C CZ  . PHE A 1 258  ? 144.284 138.644 154.437 1.00 67.73  ? 380  PHE A CZ  1 
ATOM   1178 N N   . ASN A 1 259  ? 144.219 134.777 160.549 1.00 55.61  ? 381  ASN A N   1 
ATOM   1179 C CA  . ASN A 1 259  ? 143.953 133.805 161.599 1.00 59.67  ? 381  ASN A CA  1 
ATOM   1180 C C   . ASN A 1 259  ? 142.832 132.873 161.160 1.00 58.68  ? 381  ASN A C   1 
ATOM   1181 O O   . ASN A 1 259  ? 141.742 133.330 160.803 1.00 61.58  ? 381  ASN A O   1 
ATOM   1182 C CB  . ASN A 1 259  ? 143.580 134.506 162.904 1.00 63.07  ? 381  ASN A CB  1 
ATOM   1183 C CG  . ASN A 1 259  ? 144.751 135.228 163.532 1.00 63.04  ? 381  ASN A CG  1 
ATOM   1184 O OD1 . ASN A 1 259  ? 145.868 134.716 163.563 1.00 61.02  ? 381  ASN A OD1 1 
ATOM   1185 N ND2 . ASN A 1 259  ? 144.503 136.431 164.035 1.00 65.43  ? 381  ASN A ND2 1 
ATOM   1186 N N   . LEU A 1 260  ? 143.101 131.575 161.186 1.00 56.72  ? 382  LEU A N   1 
ATOM   1187 C CA  . LEU A 1 260  ? 142.075 130.587 160.906 1.00 58.45  ? 382  LEU A CA  1 
ATOM   1188 C C   . LEU A 1 260  ? 141.223 130.380 162.151 1.00 63.13  ? 382  LEU A C   1 
ATOM   1189 O O   . LEU A 1 260  ? 141.706 130.479 163.282 1.00 64.12  ? 382  LEU A O   1 
ATOM   1190 C CB  . LEU A 1 260  ? 142.725 129.280 160.433 1.00 54.75  ? 382  LEU A CB  1 
ATOM   1191 C CG  . LEU A 1 260  ? 141.944 128.112 159.830 1.00 57.53  ? 382  LEU A CG  1 
ATOM   1192 C CD1 . LEU A 1 260  ? 142.814 127.462 158.788 1.00 55.52  ? 382  LEU A CD1 1 
ATOM   1193 C CD2 . LEU A 1 260  ? 141.579 127.067 160.863 1.00 63.21  ? 382  LEU A CD2 1 
ATOM   1194 N N   . ALA A 1 261  ? 139.942 130.091 161.934 1.00 65.65  ? 383  ALA A N   1 
ATOM   1195 C CA  . ALA A 1 261  ? 138.964 130.078 163.014 1.00 66.12  ? 383  ALA A CA  1 
ATOM   1196 C C   . ALA A 1 261  ? 138.517 128.684 163.426 1.00 69.58  ? 383  ALA A C   1 
ATOM   1197 O O   . ALA A 1 261  ? 138.448 128.397 164.624 1.00 71.68  ? 383  ALA A O   1 
ATOM   1198 C CB  . ALA A 1 261  ? 137.737 130.903 162.620 1.00 64.70  ? 383  ALA A CB  1 
ATOM   1199 N N   . ASP A 1 262  ? 138.206 127.808 162.477 1.00 68.23  ? 384  ASP A N   1 
ATOM   1200 C CA  . ASP A 1 262  ? 137.592 126.515 162.770 1.00 71.76  ? 384  ASP A CA  1 
ATOM   1201 C C   . ASP A 1 262  ? 138.636 125.410 162.652 1.00 72.95  ? 384  ASP A C   1 
ATOM   1202 O O   . ASP A 1 262  ? 138.982 124.986 161.546 1.00 75.76  ? 384  ASP A O   1 
ATOM   1203 C CB  . ASP A 1 262  ? 136.415 126.257 161.833 1.00 73.53  ? 384  ASP A CB  1 
ATOM   1204 C CG  . ASP A 1 262  ? 135.245 127.178 162.103 1.00 79.87  ? 384  ASP A CG  1 
ATOM   1205 O OD1 . ASP A 1 262  ? 135.077 127.603 163.264 1.00 80.27  ? 384  ASP A OD1 1 
ATOM   1206 O OD2 . ASP A 1 262  ? 134.492 127.476 161.153 1.00 80.68  ? 384  ASP A OD2 1 
ATOM   1207 N N   . TYR A 1 263  ? 139.122 124.928 163.793 1.00 72.35  ? 385  TYR A N   1 
ATOM   1208 C CA  . TYR A 1 263  ? 140.063 123.818 163.819 1.00 74.41  ? 385  TYR A CA  1 
ATOM   1209 C C   . TYR A 1 263  ? 139.796 122.921 165.020 1.00 82.05  ? 385  TYR A C   1 
ATOM   1210 O O   . TYR A 1 263  ? 139.501 123.395 166.120 1.00 83.01  ? 385  TYR A O   1 
ATOM   1211 C CB  . TYR A 1 263  ? 141.527 124.315 163.793 1.00 73.32  ? 385  TYR A CB  1 
ATOM   1212 C CG  . TYR A 1 263  ? 141.944 125.302 164.876 1.00 71.71  ? 385  TYR A CG  1 
ATOM   1213 C CD1 . TYR A 1 263  ? 141.846 126.682 164.655 1.00 69.59  ? 385  TYR A CD1 1 
ATOM   1214 C CD2 . TYR A 1 263  ? 142.470 124.860 166.096 1.00 73.38  ? 385  TYR A CD2 1 
ATOM   1215 C CE1 . TYR A 1 263  ? 142.241 127.598 165.632 1.00 69.59  ? 385  TYR A CE1 1 
ATOM   1216 C CE2 . TYR A 1 263  ? 142.862 125.762 167.082 1.00 74.64  ? 385  TYR A CE2 1 
ATOM   1217 C CZ  . TYR A 1 263  ? 142.745 127.125 166.839 1.00 74.22  ? 385  TYR A CZ  1 
ATOM   1218 O OH  . TYR A 1 263  ? 143.134 128.018 167.810 1.00 76.77  ? 385  TYR A OH  1 
ATOM   1219 N N   . ASP A 1 264  ? 139.898 121.613 164.788 1.00 84.39  ? 386  ASP A N   1 
ATOM   1220 C CA  . ASP A 1 264  ? 139.787 120.593 165.826 1.00 87.20  ? 386  ASP A CA  1 
ATOM   1221 C C   . ASP A 1 264  ? 141.115 119.855 165.883 1.00 87.58  ? 386  ASP A C   1 
ATOM   1222 O O   . ASP A 1 264  ? 141.559 119.300 164.871 1.00 87.03  ? 386  ASP A O   1 
ATOM   1223 C CB  . ASP A 1 264  ? 138.641 119.624 165.527 1.00 88.80  ? 386  ASP A CB  1 
ATOM   1224 C CG  . ASP A 1 264  ? 138.225 118.800 166.739 1.00 93.17  ? 386  ASP A CG  1 
ATOM   1225 O OD1 . ASP A 1 264  ? 138.753 119.029 167.849 1.00 94.90  ? 386  ASP A OD1 1 
ATOM   1226 O OD2 . ASP A 1 264  ? 137.365 117.909 166.576 1.00 93.04  ? 386  ASP A OD2 1 
ATOM   1227 N N   . CYS A 1 265  ? 141.741 119.833 167.057 1.00 91.46  ? 387  CYS A N   1 
ATOM   1228 C CA  . CYS A 1 265  ? 143.118 119.378 167.187 1.00 94.78  ? 387  CYS A CA  1 
ATOM   1229 C C   . CYS A 1 265  ? 143.251 118.340 168.289 1.00 97.96  ? 387  CYS A C   1 
ATOM   1230 O O   . CYS A 1 265  ? 142.547 118.401 169.302 1.00 97.20  ? 387  CYS A O   1 
ATOM   1231 C CB  . CYS A 1 265  ? 144.049 120.555 167.471 1.00 94.22  ? 387  CYS A CB  1 
ATOM   1232 S SG  . CYS A 1 265  ? 144.196 121.688 166.085 1.00 97.10  ? 387  CYS A SG  1 
ATOM   1233 N N   . ASP A 1 266  ? 144.166 117.401 168.082 1.00 101.05 ? 388  ASP A N   1 
ATOM   1234 C CA  . ASP A 1 266  ? 144.538 116.391 169.054 1.00 106.56 ? 388  ASP A CA  1 
ATOM   1235 C C   . ASP A 1 266  ? 145.584 117.016 169.992 1.00 107.68 ? 388  ASP A C   1 
ATOM   1236 O O   . ASP A 1 266  ? 146.132 118.086 169.715 1.00 104.96 ? 388  ASP A O   1 
ATOM   1237 C CB  . ASP A 1 266  ? 145.048 115.152 168.280 1.00 108.02 ? 388  ASP A CB  1 
ATOM   1238 C CG  . ASP A 1 266  ? 145.266 113.895 169.142 1.00 115.80 ? 388  ASP A CG  1 
ATOM   1239 O OD1 . ASP A 1 266  ? 145.062 113.928 170.376 1.00 118.53 ? 388  ASP A OD1 1 
ATOM   1240 O OD2 . ASP A 1 266  ? 145.656 112.860 168.565 1.00 115.36 ? 388  ASP A OD2 1 
ATOM   1241 N N   . GLU A 1 267  ? 145.857 116.342 171.118 1.00 110.86 ? 389  GLU A N   1 
ATOM   1242 C CA  . GLU A 1 267  ? 146.889 116.806 172.044 1.00 112.57 ? 389  GLU A CA  1 
ATOM   1243 C C   . GLU A 1 267  ? 148.304 116.537 171.530 1.00 110.68 ? 389  GLU A C   1 
ATOM   1244 O O   . GLU A 1 267  ? 149.265 117.121 172.042 1.00 109.53 ? 389  GLU A O   1 
ATOM   1245 C CB  . GLU A 1 267  ? 146.695 116.156 173.414 1.00 116.41 ? 389  GLU A CB  1 
ATOM   1246 C CG  . GLU A 1 267  ? 145.386 116.520 174.089 1.00 119.41 ? 389  GLU A CG  1 
ATOM   1247 C CD  . GLU A 1 267  ? 145.303 116.017 175.517 1.00 124.58 ? 389  GLU A CD  1 
ATOM   1248 O OE1 . GLU A 1 267  ? 146.257 115.351 175.972 1.00 120.23 ? 389  GLU A OE1 1 
ATOM   1249 O OE2 . GLU A 1 267  ? 144.285 116.293 176.184 1.00 126.84 ? 389  GLU A OE2 1 
ATOM   1250 N N   . TYR A 1 268  ? 148.456 115.668 170.523 1.00 111.19 ? 390  TYR A N   1 
ATOM   1251 C CA  . TYR A 1 268  ? 149.726 115.497 169.824 1.00 112.09 ? 390  TYR A CA  1 
ATOM   1252 C C   . TYR A 1 268  ? 149.879 116.422 168.619 1.00 107.76 ? 390  TYR A C   1 
ATOM   1253 O O   . TYR A 1 268  ? 150.751 116.158 167.782 1.00 103.60 ? 390  TYR A O   1 
ATOM   1254 C CB  . TYR A 1 268  ? 149.894 114.045 169.371 1.00 114.69 ? 390  TYR A CB  1 
ATOM   1255 C CG  . TYR A 1 268  ? 149.940 113.046 170.502 1.00 118.61 ? 390  TYR A CG  1 
ATOM   1256 C CD1 . TYR A 1 268  ? 151.132 112.820 171.203 1.00 119.07 ? 390  TYR A CD1 1 
ATOM   1257 C CD2 . TYR A 1 268  ? 148.798 112.321 170.866 1.00 118.65 ? 390  TYR A CD2 1 
ATOM   1258 C CE1 . TYR A 1 268  ? 151.187 111.898 172.247 1.00 122.04 ? 390  TYR A CE1 1 
ATOM   1259 C CE2 . TYR A 1 268  ? 148.840 111.393 171.910 1.00 121.35 ? 390  TYR A CE2 1 
ATOM   1260 C CZ  . TYR A 1 268  ? 150.038 111.193 172.591 1.00 124.21 ? 390  TYR A CZ  1 
ATOM   1261 O OH  . TYR A 1 268  ? 150.093 110.282 173.621 1.00 125.38 ? 390  TYR A OH  1 
ATOM   1262 N N   . TYR A 1 269  ? 149.027 117.456 168.511 1.00 105.62 ? 391  TYR A N   1 
ATOM   1263 C CA  . TYR A 1 269  ? 149.032 118.559 167.546 1.00 99.83  ? 391  TYR A CA  1 
ATOM   1264 C C   . TYR A 1 269  ? 148.873 118.085 166.107 1.00 93.32  ? 391  TYR A C   1 
ATOM   1265 O O   . TYR A 1 269  ? 149.466 118.649 165.184 1.00 90.20  ? 391  TYR A O   1 
ATOM   1266 C CB  . TYR A 1 269  ? 150.281 119.437 167.724 1.00 99.35  ? 391  TYR A CB  1 
ATOM   1267 C CG  . TYR A 1 269  ? 150.246 120.166 169.045 1.00 100.47 ? 391  TYR A CG  1 
ATOM   1268 C CD1 . TYR A 1 269  ? 149.492 121.332 169.185 1.00 98.46  ? 391  TYR A CD1 1 
ATOM   1269 C CD2 . TYR A 1 269  ? 150.914 119.658 170.168 1.00 102.67 ? 391  TYR A CD2 1 
ATOM   1270 C CE1 . TYR A 1 269  ? 149.427 122.001 170.403 1.00 106.84 ? 391  TYR A CE1 1 
ATOM   1271 C CE2 . TYR A 1 269  ? 150.851 120.321 171.400 1.00 104.55 ? 391  TYR A CE2 1 
ATOM   1272 C CZ  . TYR A 1 269  ? 150.103 121.491 171.502 1.00 108.68 ? 391  TYR A CZ  1 
ATOM   1273 O OH  . TYR A 1 269  ? 150.020 122.161 172.700 1.00 106.28 ? 391  TYR A OH  1 
ATOM   1274 N N   . VAL A 1 270  ? 148.064 117.048 165.920 1.00 94.46  ? 392  VAL A N   1 
ATOM   1275 C CA  . VAL A 1 270  ? 147.533 116.690 164.612 1.00 90.29  ? 392  VAL A CA  1 
ATOM   1276 C C   . VAL A 1 270  ? 146.231 117.470 164.463 1.00 89.03  ? 392  VAL A C   1 
ATOM   1277 O O   . VAL A 1 270  ? 145.235 117.166 165.124 1.00 91.51  ? 392  VAL A O   1 
ATOM   1278 C CB  . VAL A 1 270  ? 147.311 115.177 164.495 1.00 91.22  ? 392  VAL A CB  1 
ATOM   1279 C CG1 . VAL A 1 270  ? 146.668 114.819 163.170 1.00 88.19  ? 392  VAL A CG1 1 
ATOM   1280 C CG2 . VAL A 1 270  ? 148.622 114.436 164.679 1.00 94.23  ? 392  VAL A CG2 1 
ATOM   1281 N N   . CYS A 1 271  ? 146.245 118.500 163.623 1.00 88.43  ? 393  CYS A N   1 
ATOM   1282 C CA  . CYS A 1 271  ? 145.177 119.488 163.586 1.00 85.56  ? 393  CYS A CA  1 
ATOM   1283 C C   . CYS A 1 271  ? 144.344 119.352 162.323 1.00 86.27  ? 393  CYS A C   1 
ATOM   1284 O O   . CYS A 1 271  ? 144.866 119.442 161.210 1.00 88.18  ? 393  CYS A O   1 
ATOM   1285 C CB  . CYS A 1 271  ? 145.744 120.901 163.679 1.00 83.77  ? 393  CYS A CB  1 
ATOM   1286 S SG  . CYS A 1 271  ? 146.068 121.406 165.364 1.00 94.84  ? 393  CYS A SG  1 
ATOM   1287 N N   . GLU A 1 272  ? 143.042 119.169 162.507 1.00 84.74  ? 394  GLU A N   1 
ATOM   1288 C CA  . GLU A 1 272  ? 142.089 119.030 161.416 1.00 81.62  ? 394  GLU A CA  1 
ATOM   1289 C C   . GLU A 1 272  ? 141.442 120.376 161.129 1.00 79.87  ? 394  GLU A C   1 
ATOM   1290 O O   . GLU A 1 272  ? 141.008 121.073 162.049 1.00 80.50  ? 394  GLU A O   1 
ATOM   1291 C CB  . GLU A 1 272  ? 141.017 118.003 161.775 1.00 83.02  ? 394  GLU A CB  1 
ATOM   1292 C CG  . GLU A 1 272  ? 140.212 117.492 160.604 1.00 85.85  ? 394  GLU A CG  1 
ATOM   1293 C CD  . GLU A 1 272  ? 139.576 116.148 160.888 1.00 90.23  ? 394  GLU A CD  1 
ATOM   1294 O OE1 . GLU A 1 272  ? 138.338 116.096 161.031 1.00 91.75  ? 394  GLU A OE1 1 
ATOM   1295 O OE2 . GLU A 1 272  ? 140.314 115.145 160.967 1.00 88.97  ? 394  GLU A OE2 1 
ATOM   1296 N N   . ILE A 1 273  ? 141.375 120.741 159.852 1.00 75.29  ? 395  ILE A N   1 
ATOM   1297 C CA  . ILE A 1 273  ? 140.846 122.034 159.434 1.00 71.04  ? 395  ILE A CA  1 
ATOM   1298 C C   . ILE A 1 273  ? 139.383 121.859 159.055 1.00 74.42  ? 395  ILE A C   1 
ATOM   1299 O O   . ILE A 1 273  ? 139.058 121.100 158.134 1.00 75.50  ? 395  ILE A O   1 
ATOM   1300 C CB  . ILE A 1 273  ? 141.652 122.622 158.266 1.00 66.64  ? 395  ILE A CB  1 
ATOM   1301 C CG1 . ILE A 1 273  ? 143.106 122.846 158.681 1.00 68.65  ? 395  ILE A CG1 1 
ATOM   1302 C CG2 . ILE A 1 273  ? 141.031 123.922 157.791 1.00 65.41  ? 395  ILE A CG2 1 
ATOM   1303 C CD1 . ILE A 1 273  ? 143.274 123.809 159.835 1.00 72.35  ? 395  ILE A CD1 1 
ATOM   1304 N N   . LEU A 1 274  ? 138.502 122.561 159.763 1.00 75.53  ? 396  LEU A N   1 
ATOM   1305 C CA  . LEU A 1 274  ? 137.070 122.512 159.511 1.00 73.91  ? 396  LEU A CA  1 
ATOM   1306 C C   . LEU A 1 274  ? 136.542 123.769 158.838 1.00 73.66  ? 396  LEU A C   1 
ATOM   1307 O O   . LEU A 1 274  ? 135.358 123.816 158.492 1.00 74.87  ? 396  LEU A O   1 
ATOM   1308 C CB  . LEU A 1 274  ? 136.295 122.270 160.815 1.00 72.83  ? 396  LEU A CB  1 
ATOM   1309 C CG  . LEU A 1 274  ? 136.083 120.856 161.379 1.00 74.37  ? 396  LEU A CG  1 
ATOM   1310 C CD1 . LEU A 1 274  ? 137.327 120.226 161.992 1.00 76.44  ? 396  LEU A CD1 1 
ATOM   1311 C CD2 . LEU A 1 274  ? 134.946 120.877 162.390 1.00 76.43  ? 396  LEU A CD2 1 
ATOM   1312 N N   . GLU A 1 275  ? 137.380 124.788 158.658 1.00 71.54  ? 397  GLU A N   1 
ATOM   1313 C CA  . GLU A 1 275  ? 136.971 126.009 157.978 1.00 68.55  ? 397  GLU A CA  1 
ATOM   1314 C C   . GLU A 1 275  ? 136.896 125.747 156.481 1.00 64.99  ? 397  GLU A C   1 
ATOM   1315 O O   . GLU A 1 275  ? 137.818 125.161 155.904 1.00 64.08  ? 397  GLU A O   1 
ATOM   1316 C CB  . GLU A 1 275  ? 137.949 127.142 158.287 1.00 68.69  ? 397  GLU A CB  1 
ATOM   1317 C CG  . GLU A 1 275  ? 137.603 128.473 157.639 1.00 66.99  ? 397  GLU A CG  1 
ATOM   1318 C CD  . GLU A 1 275  ? 138.352 129.633 158.257 1.00 66.37  ? 397  GLU A CD  1 
ATOM   1319 O OE1 . GLU A 1 275  ? 138.716 129.535 159.444 1.00 67.91  ? 397  GLU A OE1 1 
ATOM   1320 O OE2 . GLU A 1 275  ? 138.579 130.642 157.557 1.00 63.66  ? 397  GLU A OE2 1 
ATOM   1321 N N   . ALA A 1 276  ? 135.789 126.156 155.862 1.00 67.00  ? 398  ALA A N   1 
ATOM   1322 C CA  . ALA A 1 276  ? 135.621 125.979 154.427 1.00 64.58  ? 398  ALA A CA  1 
ATOM   1323 C C   . ALA A 1 276  ? 136.481 126.980 153.668 1.00 62.29  ? 398  ALA A C   1 
ATOM   1324 O O   . ALA A 1 276  ? 136.372 128.194 153.860 1.00 65.71  ? 398  ALA A O   1 
ATOM   1325 C CB  . ALA A 1 276  ? 134.151 126.140 154.042 1.00 62.62  ? 398  ALA A CB  1 
ATOM   1326 N N   . LEU A 1 277  ? 137.346 126.455 152.810 1.00 57.93  ? 399  LEU A N   1 
ATOM   1327 C CA  . LEU A 1 277  ? 138.358 127.233 152.118 1.00 56.51  ? 399  LEU A CA  1 
ATOM   1328 C C   . LEU A 1 277  ? 137.947 127.487 150.673 1.00 56.62  ? 399  LEU A C   1 
ATOM   1329 O O   . LEU A 1 277  ? 137.052 126.829 150.135 1.00 57.50  ? 399  LEU A O   1 
ATOM   1330 C CB  . LEU A 1 277  ? 139.709 126.516 152.167 1.00 57.19  ? 399  LEU A CB  1 
ATOM   1331 C CG  . LEU A 1 277  ? 140.257 126.148 153.547 1.00 58.59  ? 399  LEU A CG  1 
ATOM   1332 C CD1 . LEU A 1 277  ? 141.118 124.902 153.468 1.00 53.94  ? 399  LEU A CD1 1 
ATOM   1333 C CD2 . LEU A 1 277  ? 141.051 127.305 154.129 1.00 53.60  ? 399  LEU A CD2 1 
ATOM   1334 N N   . ILE A 1 278  ? 138.618 128.453 150.052 1.00 56.59  ? 400  ILE A N   1 
ATOM   1335 C CA  . ILE A 1 278  ? 138.313 128.835 148.667 1.00 50.79  ? 400  ILE A CA  1 
ATOM   1336 C C   . ILE A 1 278  ? 138.905 127.800 147.715 1.00 51.82  ? 400  ILE A C   1 
ATOM   1337 O O   . ILE A 1 278  ? 140.105 127.481 147.826 1.00 54.12  ? 400  ILE A O   1 
ATOM   1338 C CB  . ILE A 1 278  ? 138.863 130.236 148.362 1.00 50.24  ? 400  ILE A CB  1 
ATOM   1339 C CG1 . ILE A 1 278  ? 138.411 131.225 149.437 1.00 51.56  ? 400  ILE A CG1 1 
ATOM   1340 C CG2 . ILE A 1 278  ? 138.406 130.690 146.986 1.00 50.67  ? 400  ILE A CG2 1 
ATOM   1341 C CD1 . ILE A 1 278  ? 138.920 132.638 149.243 1.00 52.90  ? 400  ILE A CD1 1 
ATOM   1342 N N   . PRO A 1 279  ? 138.119 127.223 146.795 1.00 49.94  ? 401  PRO A N   1 
ATOM   1343 C CA  . PRO A 1 279  ? 138.659 126.187 145.901 1.00 50.05  ? 401  PRO A CA  1 
ATOM   1344 C C   . PRO A 1 279  ? 139.552 126.754 144.807 1.00 50.95  ? 401  PRO A C   1 
ATOM   1345 O O   . PRO A 1 279  ? 139.313 127.858 144.306 1.00 51.70  ? 401  PRO A O   1 
ATOM   1346 C CB  . PRO A 1 279  ? 137.402 125.551 145.302 1.00 43.98  ? 401  PRO A CB  1 
ATOM   1347 C CG  . PRO A 1 279  ? 136.321 125.875 146.254 1.00 44.48  ? 401  PRO A CG  1 
ATOM   1348 C CD  . PRO A 1 279  ? 136.647 127.233 146.768 1.00 47.76  ? 401  PRO A CD  1 
ATOM   1349 N N   . TYR A 1 280  ? 140.557 125.943 144.434 1.00 49.94  ? 402  TYR A N   1 
ATOM   1350 C CA  . TYR A 1 280  ? 141.630 126.217 143.460 1.00 53.28  ? 402  TYR A CA  1 
ATOM   1351 C C   . TYR A 1 280  ? 142.385 127.498 143.845 1.00 54.97  ? 402  TYR A C   1 
ATOM   1352 O O   . TYR A 1 280  ? 142.338 128.531 143.179 1.00 57.49  ? 402  TYR A O   1 
ATOM   1353 C CB  . TYR A 1 280  ? 141.077 126.215 142.017 1.00 56.24  ? 402  TYR A CB  1 
ATOM   1354 C CG  . TYR A 1 280  ? 142.058 126.423 140.862 1.00 59.76  ? 402  TYR A CG  1 
ATOM   1355 C CD1 . TYR A 1 280  ? 142.909 125.387 140.459 1.00 60.21  ? 402  TYR A CD1 1 
ATOM   1356 C CD2 . TYR A 1 280  ? 142.066 127.618 140.120 1.00 63.07  ? 402  TYR A CD2 1 
ATOM   1357 C CE1 . TYR A 1 280  ? 143.797 125.559 139.394 1.00 66.14  ? 402  TYR A CE1 1 
ATOM   1358 C CE2 . TYR A 1 280  ? 142.954 127.806 139.066 1.00 69.27  ? 402  TYR A CE2 1 
ATOM   1359 C CZ  . TYR A 1 280  ? 143.806 126.770 138.705 1.00 73.90  ? 402  TYR A CZ  1 
ATOM   1360 O OH  . TYR A 1 280  ? 144.671 126.952 137.651 1.00 78.04  ? 402  TYR A OH  1 
ATOM   1361 N N   . THR A 1 281  ? 142.982 127.447 145.036 1.00 54.25  ? 403  THR A N   1 
ATOM   1362 C CA  . THR A 1 281  ? 143.893 128.470 145.543 1.00 54.83  ? 403  THR A CA  1 
ATOM   1363 C C   . THR A 1 281  ? 145.073 127.767 146.188 1.00 56.47  ? 403  THR A C   1 
ATOM   1364 O O   . THR A 1 281  ? 144.978 126.585 146.525 1.00 54.86  ? 403  THR A O   1 
ATOM   1365 C CB  . THR A 1 281  ? 143.251 129.404 146.585 1.00 52.41  ? 403  THR A CB  1 
ATOM   1366 O OG1 . THR A 1 281  ? 142.824 128.634 147.706 1.00 57.09  ? 403  THR A OG1 1 
ATOM   1367 C CG2 . THR A 1 281  ? 142.115 130.275 146.054 1.00 52.02  ? 403  THR A CG2 1 
ATOM   1368 N N   . GLN A 1 282  ? 146.170 128.494 146.368 1.00 56.02  ? 404  GLN A N   1 
ATOM   1369 C CA  . GLN A 1 282  ? 147.311 127.960 147.096 1.00 57.50  ? 404  GLN A CA  1 
ATOM   1370 C C   . GLN A 1 282  ? 147.294 128.507 148.519 1.00 58.91  ? 404  GLN A C   1 
ATOM   1371 O O   . GLN A 1 282  ? 147.137 129.715 148.723 1.00 61.36  ? 404  GLN A O   1 
ATOM   1372 C CB  . GLN A 1 282  ? 148.614 128.332 146.394 1.00 59.68  ? 404  GLN A CB  1 
ATOM   1373 C CG  . GLN A 1 282  ? 148.818 127.767 144.996 1.00 59.05  ? 404  GLN A CG  1 
ATOM   1374 C CD  . GLN A 1 282  ? 148.957 126.266 144.967 1.00 62.90  ? 404  GLN A CD  1 
ATOM   1375 O OE1 . GLN A 1 282  ? 149.573 125.668 145.839 1.00 67.03  ? 404  GLN A OE1 1 
ATOM   1376 N NE2 . GLN A 1 282  ? 148.408 125.651 143.938 1.00 63.21  ? 404  GLN A NE2 1 
ATOM   1377 N N   . TYR A 1 283  ? 147.456 127.624 149.504 1.00 54.83  ? 405  TYR A N   1 
ATOM   1378 C CA  . TYR A 1 283  ? 147.403 127.985 150.916 1.00 52.39  ? 405  TYR A CA  1 
ATOM   1379 C C   . TYR A 1 283  ? 148.671 127.529 151.617 1.00 58.19  ? 405  TYR A C   1 
ATOM   1380 O O   . TYR A 1 283  ? 149.070 126.368 151.492 1.00 62.62  ? 405  TYR A O   1 
ATOM   1381 C CB  . TYR A 1 283  ? 146.195 127.356 151.614 1.00 52.84  ? 405  TYR A CB  1 
ATOM   1382 C CG  . TYR A 1 283  ? 144.919 128.155 151.543 1.00 56.10  ? 405  TYR A CG  1 
ATOM   1383 C CD1 . TYR A 1 283  ? 144.858 129.445 152.079 1.00 57.57  ? 405  TYR A CD1 1 
ATOM   1384 C CD2 . TYR A 1 283  ? 143.768 127.613 150.966 1.00 54.10  ? 405  TYR A CD2 1 
ATOM   1385 C CE1 . TYR A 1 283  ? 143.677 130.182 152.032 1.00 56.88  ? 405  TYR A CE1 1 
ATOM   1386 C CE2 . TYR A 1 283  ? 142.585 128.345 150.912 1.00 52.79  ? 405  TYR A CE2 1 
ATOM   1387 C CZ  . TYR A 1 283  ? 142.550 129.624 151.441 1.00 54.63  ? 405  TYR A CZ  1 
ATOM   1388 O OH  . TYR A 1 283  ? 141.379 130.346 151.386 1.00 56.99  ? 405  TYR A OH  1 
ATOM   1389 N N   . ARG A 1 284  ? 149.296 128.441 152.351 1.00 54.84  ? 406  ARG A N   1 
ATOM   1390 C CA  . ARG A 1 284  ? 150.416 128.129 153.221 1.00 44.95  ? 406  ARG A CA  1 
ATOM   1391 C C   . ARG A 1 284  ? 150.026 128.417 154.668 1.00 48.63  ? 406  ARG A C   1 
ATOM   1392 O O   . ARG A 1 284  ? 149.414 129.445 154.965 1.00 54.25  ? 406  ARG A O   1 
ATOM   1393 C CB  . ARG A 1 284  ? 151.653 128.926 152.785 1.00 48.21  ? 406  ARG A CB  1 
ATOM   1394 C CG  . ARG A 1 284  ? 152.918 128.597 153.529 1.00 56.00  ? 406  ARG A CG  1 
ATOM   1395 C CD  . ARG A 1 284  ? 154.131 129.352 152.999 1.00 58.76  ? 406  ARG A CD  1 
ATOM   1396 N NE  . ARG A 1 284  ? 154.118 130.801 153.137 1.00 63.56  ? 406  ARG A NE  1 
ATOM   1397 C CZ  . ARG A 1 284  ? 154.066 131.638 152.110 1.00 67.62  ? 406  ARG A CZ  1 
ATOM   1398 N NH1 . ARG A 1 284  ? 153.911 131.202 150.868 1.00 68.20  ? 406  ARG A NH1 1 
ATOM   1399 N NH2 . ARG A 1 284  ? 154.208 132.940 152.327 1.00 68.77  ? 406  ARG A NH2 1 
ATOM   1400 N N   . PHE A 1 285  ? 150.379 127.497 155.564 1.00 47.34  ? 407  PHE A N   1 
ATOM   1401 C CA  . PHE A 1 285  ? 149.915 127.506 156.945 1.00 43.06  ? 407  PHE A CA  1 
ATOM   1402 C C   . PHE A 1 285  ? 151.088 127.564 157.915 1.00 46.59  ? 407  PHE A C   1 
ATOM   1403 O O   . PHE A 1 285  ? 152.201 127.134 157.602 1.00 55.63  ? 407  PHE A O   1 
ATOM   1404 C CB  . PHE A 1 285  ? 149.088 126.258 157.278 1.00 42.63  ? 407  PHE A CB  1 
ATOM   1405 C CG  . PHE A 1 285  ? 147.869 126.076 156.427 1.00 45.24  ? 407  PHE A CG  1 
ATOM   1406 C CD1 . PHE A 1 285  ? 146.695 126.762 156.726 1.00 44.14  ? 407  PHE A CD1 1 
ATOM   1407 C CD2 . PHE A 1 285  ? 147.885 125.187 155.352 1.00 47.18  ? 407  PHE A CD2 1 
ATOM   1408 C CE1 . PHE A 1 285  ? 145.551 126.587 155.954 1.00 45.07  ? 407  PHE A CE1 1 
ATOM   1409 C CE2 . PHE A 1 285  ? 146.747 125.000 154.569 1.00 45.06  ? 407  PHE A CE2 1 
ATOM   1410 C CZ  . PHE A 1 285  ? 145.580 125.704 154.875 1.00 44.98  ? 407  PHE A CZ  1 
ATOM   1411 N N   . ARG A 1 286  ? 150.819 128.093 159.110 1.00 43.20  ? 408  ARG A N   1 
ATOM   1412 C CA  . ARG A 1 286  ? 151.778 128.079 160.208 1.00 39.99  ? 408  ARG A CA  1 
ATOM   1413 C C   . ARG A 1 286  ? 151.031 128.078 161.533 1.00 40.62  ? 408  ARG A C   1 
ATOM   1414 O O   . ARG A 1 286  ? 149.831 128.353 161.592 1.00 46.66  ? 408  ARG A O   1 
ATOM   1415 C CB  . ARG A 1 286  ? 152.746 129.265 160.140 1.00 43.09  ? 408  ARG A CB  1 
ATOM   1416 C CG  . ARG A 1 286  ? 152.199 130.574 160.658 1.00 41.47  ? 408  ARG A CG  1 
ATOM   1417 C CD  . ARG A 1 286  ? 153.223 131.672 160.475 1.00 45.80  ? 408  ARG A CD  1 
ATOM   1418 N NE  . ARG A 1 286  ? 152.687 132.986 160.797 1.00 48.53  ? 408  ARG A NE  1 
ATOM   1419 C CZ  . ARG A 1 286  ? 153.348 134.122 160.637 1.00 50.70  ? 408  ARG A CZ  1 
ATOM   1420 N NH1 . ARG A 1 286  ? 154.582 134.141 160.162 1.00 50.90  ? 408  ARG A NH1 1 
ATOM   1421 N NH2 . ARG A 1 286  ? 152.758 135.269 160.960 1.00 51.34  ? 408  ARG A NH2 1 
ATOM   1422 N N   . PHE A 1 287  ? 151.761 127.750 162.599 1.00 43.13  ? 409  PHE A N   1 
ATOM   1423 C CA  . PHE A 1 287  ? 151.235 127.719 163.962 1.00 41.65  ? 409  PHE A CA  1 
ATOM   1424 C C   . PHE A 1 287  ? 151.775 128.924 164.724 1.00 47.92  ? 409  PHE A C   1 
ATOM   1425 O O   . PHE A 1 287  ? 152.971 128.988 165.022 1.00 54.26  ? 409  PHE A O   1 
ATOM   1426 C CB  . PHE A 1 287  ? 151.653 126.436 164.670 1.00 41.31  ? 409  PHE A CB  1 
ATOM   1427 C CG  . PHE A 1 287  ? 150.773 125.266 164.402 1.00 38.34  ? 409  PHE A CG  1 
ATOM   1428 C CD1 . PHE A 1 287  ? 149.693 124.990 165.236 1.00 39.91  ? 409  PHE A CD1 1 
ATOM   1429 C CD2 . PHE A 1 287  ? 151.040 124.424 163.327 1.00 38.95  ? 409  PHE A CD2 1 
ATOM   1430 C CE1 . PHE A 1 287  ? 148.880 123.884 164.999 1.00 42.89  ? 409  PHE A CE1 1 
ATOM   1431 C CE2 . PHE A 1 287  ? 150.233 123.321 163.072 1.00 40.83  ? 409  PHE A CE2 1 
ATOM   1432 C CZ  . PHE A 1 287  ? 149.154 123.053 163.913 1.00 43.50  ? 409  PHE A CZ  1 
ATOM   1433 N N   . GLU A 1 288  ? 150.902 129.866 165.062 1.00 48.52  ? 410  GLU A N   1 
ATOM   1434 C CA  . GLU A 1 288  ? 151.290 130.979 165.920 1.00 55.49  ? 410  GLU A CA  1 
ATOM   1435 C C   . GLU A 1 288  ? 151.167 130.549 167.376 1.00 60.74  ? 410  GLU A C   1 
ATOM   1436 O O   . GLU A 1 288  ? 150.117 130.049 167.790 1.00 61.19  ? 410  GLU A O   1 
ATOM   1437 C CB  . GLU A 1 288  ? 150.421 132.202 165.632 1.00 56.76  ? 410  GLU A CB  1 
ATOM   1438 C CG  . GLU A 1 288  ? 150.546 133.317 166.654 1.00 61.65  ? 410  GLU A CG  1 
ATOM   1439 C CD  . GLU A 1 288  ? 149.524 134.424 166.471 1.00 69.02  ? 410  GLU A CD  1 
ATOM   1440 O OE1 . GLU A 1 288  ? 148.347 134.222 166.828 1.00 71.83  ? 410  GLU A OE1 1 
ATOM   1441 O OE2 . GLU A 1 288  ? 149.902 135.502 165.970 1.00 71.20  ? 410  GLU A OE2 1 
ATOM   1442 N N   . LEU A 1 289  ? 152.277 130.604 168.122 1.00 62.74  ? 411  LEU A N   1 
ATOM   1443 C CA  . LEU A 1 289  ? 152.292 130.150 169.539 1.00 63.12  ? 411  LEU A CA  1 
ATOM   1444 C C   . LEU A 1 289  ? 152.486 131.359 170.445 1.00 66.97  ? 411  LEU A C   1 
ATOM   1445 O O   . LEU A 1 289  ? 153.618 131.834 170.537 1.00 68.13  ? 411  LEU A O   1 
ATOM   1446 C CB  . LEU A 1 289  ? 153.451 129.184 169.744 1.00 62.18  ? 411  LEU A CB  1 
ATOM   1447 C CG  . LEU A 1 289  ? 153.072 127.721 169.930 1.00 65.23  ? 411  LEU A CG  1 
ATOM   1448 C CD1 . LEU A 1 289  ? 154.329 126.881 170.015 1.00 67.97  ? 411  LEU A CD1 1 
ATOM   1449 C CD2 . LEU A 1 289  ? 152.228 127.544 171.181 1.00 63.47  ? 411  LEU A CD2 1 
ATOM   1450 N N   . PRO A 1 290  ? 151.430 131.873 171.107 1.00 68.90  ? 412  PRO A N   1 
ATOM   1451 C CA  . PRO A 1 290  ? 151.557 132.990 172.023 1.00 67.63  ? 412  PRO A CA  1 
ATOM   1452 C C   . PRO A 1 290  ? 151.816 132.440 173.426 1.00 70.93  ? 412  PRO A C   1 
ATOM   1453 O O   . PRO A 1 290  ? 150.994 131.694 173.915 1.00 71.38  ? 412  PRO A O   1 
ATOM   1454 C CB  . PRO A 1 290  ? 150.165 133.627 171.997 1.00 68.50  ? 412  PRO A CB  1 
ATOM   1455 C CG  . PRO A 1 290  ? 149.372 132.838 170.973 1.00 69.71  ? 412  PRO A CG  1 
ATOM   1456 C CD  . PRO A 1 290  ? 150.043 131.485 170.922 1.00 70.24  ? 412  PRO A CD  1 
ATOM   1457 N N   . PHE A 1 291  ? 152.978 132.764 174.000 1.00 72.63  ? 413  PHE A N   1 
ATOM   1458 C CA  . PHE A 1 291  ? 153.347 132.236 175.338 1.00 70.68  ? 413  PHE A CA  1 
ATOM   1459 C C   . PHE A 1 291  ? 152.468 132.865 176.423 1.00 69.05  ? 413  PHE A C   1 
ATOM   1460 O O   . PHE A 1 291  ? 151.924 132.128 177.258 1.00 66.64  ? 413  PHE A O   1 
ATOM   1461 C CB  . PHE A 1 291  ? 154.871 132.255 175.489 1.00 70.15  ? 413  PHE A CB  1 
ATOM   1462 C CG  . PHE A 1 291  ? 155.493 131.060 174.824 1.00 66.93  ? 413  PHE A CG  1 
ATOM   1463 C CD1 . PHE A 1 291  ? 155.793 131.079 173.476 1.00 66.01  ? 413  PHE A CD1 1 
ATOM   1464 C CD2 . PHE A 1 291  ? 155.696 129.890 175.534 1.00 66.59  ? 413  PHE A CD2 1 
ATOM   1465 C CE1 . PHE A 1 291  ? 156.325 129.963 172.857 1.00 69.58  ? 413  PHE A CE1 1 
ATOM   1466 C CE2 . PHE A 1 291  ? 156.232 128.773 174.915 1.00 71.39  ? 413  PHE A CE2 1 
ATOM   1467 C CZ  . PHE A 1 291  ? 156.541 128.814 173.577 1.00 72.17  ? 413  PHE A CZ  1 
ATOM   1468 N N   . GLY A 1 292  ? 152.263 134.174 176.343 1.00 70.33  ? 414  GLY A N   1 
ATOM   1469 C CA  . GLY A 1 292  ? 151.442 134.899 177.327 1.00 71.79  ? 414  GLY A CA  1 
ATOM   1470 C C   . GLY A 1 292  ? 150.871 136.122 176.639 1.00 71.26  ? 414  GLY A C   1 
ATOM   1471 O O   . GLY A 1 292  ? 151.053 136.227 175.415 1.00 74.23  ? 414  GLY A O   1 
ATOM   1472 N N   . GLU A 1 293  ? 150.207 137.014 177.372 1.00 138.39 ? 415  GLU A N   1 
ATOM   1473 C CA  . GLU A 1 293  ? 149.474 138.138 176.728 1.00 139.45 ? 415  GLU A CA  1 
ATOM   1474 C C   . GLU A 1 293  ? 150.447 139.020 175.934 1.00 136.53 ? 415  GLU A C   1 
ATOM   1475 O O   . GLU A 1 293  ? 150.003 139.625 174.942 1.00 135.76 ? 415  GLU A O   1 
ATOM   1476 C CB  . GLU A 1 293  ? 148.676 138.927 177.763 1.00 143.73 ? 415  GLU A CB  1 
ATOM   1477 C CG  . GLU A 1 293  ? 147.661 138.074 178.502 1.00 144.63 ? 415  GLU A CG  1 
ATOM   1478 C CD  . GLU A 1 293  ? 146.764 138.837 179.461 1.00 148.06 ? 415  GLU A CD  1 
ATOM   1479 O OE1 . GLU A 1 293  ? 146.874 140.079 179.512 1.00 148.36 ? 415  GLU A OE1 1 
ATOM   1480 O OE2 . GLU A 1 293  ? 145.957 138.186 180.154 1.00 148.71 ? 415  GLU A OE2 1 
ATOM   1481 N N   . ASN A 1 294  ? 151.714 139.095 176.354 1.00 136.11 ? 416  ASN A N   1 
ATOM   1482 C CA  . ASN A 1 294  ? 152.708 139.966 175.670 1.00 135.69 ? 416  ASN A CA  1 
ATOM   1483 C C   . ASN A 1 294  ? 152.819 139.566 174.196 1.00 136.06 ? 416  ASN A C   1 
ATOM   1484 O O   . ASN A 1 294  ? 152.929 138.358 173.920 1.00 134.11 ? 416  ASN A O   1 
ATOM   1485 C CB  . ASN A 1 294  ? 154.078 139.876 176.347 1.00 131.72 ? 416  ASN A CB  1 
ATOM   1486 C CG  . ASN A 1 294  ? 155.153 140.701 175.673 1.00 133.31 ? 416  ASN A CG  1 
ATOM   1487 O OD1 . ASN A 1 294  ? 154.863 141.685 174.994 1.00 134.80 ? 416  ASN A OD1 1 
ATOM   1488 N ND2 . ASN A 1 294  ? 156.404 140.319 175.869 1.00 131.92 ? 416  ASN A ND2 1 
ATOM   1489 N N   . ARG A 1 295  ? 152.806 140.551 173.293 1.00 136.93 ? 417  ARG A N   1 
ATOM   1490 C CA  . ARG A 1 295  ? 152.897 140.286 171.831 1.00 136.25 ? 417  ARG A CA  1 
ATOM   1491 C C   . ARG A 1 295  ? 154.253 139.671 171.473 1.00 133.65 ? 417  ARG A C   1 
ATOM   1492 O O   . ARG A 1 295  ? 154.282 138.802 170.589 1.00 130.20 ? 417  ARG A O   1 
ATOM   1493 C CB  . ARG A 1 295  ? 152.680 141.581 171.046 1.00 135.75 ? 417  ARG A CB  1 
ATOM   1494 N N   . ASP A 1 296  ? 155.334 140.122 172.111 1.00 133.92 ? 418  ASP A N   1 
ATOM   1495 C CA  . ASP A 1 296  ? 156.700 139.620 171.793 1.00 131.95 ? 418  ASP A CA  1 
ATOM   1496 C C   . ASP A 1 296  ? 156.783 138.123 172.104 1.00 128.55 ? 418  ASP A C   1 
ATOM   1497 O O   . ASP A 1 296  ? 157.593 137.438 171.457 1.00 127.55 ? 418  ASP A O   1 
ATOM   1498 C CB  . ASP A 1 296  ? 157.775 140.403 172.550 1.00 131.68 ? 418  ASP A CB  1 
ATOM   1499 C CG  . ASP A 1 296  ? 159.189 140.087 172.095 1.00 133.58 ? 418  ASP A CG  1 
ATOM   1500 O OD1 . ASP A 1 296  ? 160.110 140.199 172.927 1.00 133.83 ? 418  ASP A OD1 1 
ATOM   1501 O OD2 . ASP A 1 296  ? 159.361 139.741 170.907 1.00 133.61 ? 418  ASP A OD2 1 
ATOM   1502 N N   . GLU A 1 297  ? 155.981 137.637 173.054 1.00 125.69 ? 419  GLU A N   1 
ATOM   1503 C CA  . GLU A 1 297  ? 156.048 136.212 173.466 1.00 120.16 ? 419  GLU A CA  1 
ATOM   1504 C C   . GLU A 1 297  ? 155.694 135.312 172.287 1.00 113.54 ? 419  GLU A C   1 
ATOM   1505 O O   . GLU A 1 297  ? 156.099 134.140 172.316 1.00 112.53 ? 419  GLU A O   1 
ATOM   1506 C CB  . GLU A 1 297  ? 155.097 135.924 174.624 1.00 124.85 ? 419  GLU A CB  1 
ATOM   1507 C CG  . GLU A 1 297  ? 155.403 136.719 175.880 1.00 126.81 ? 419  GLU A CG  1 
ATOM   1508 C CD  . GLU A 1 297  ? 156.790 136.575 176.486 1.00 130.27 ? 419  GLU A CD  1 
ATOM   1509 O OE1 . GLU A 1 297  ? 157.153 137.423 177.325 1.00 128.48 ? 419  GLU A OE1 1 
ATOM   1510 O OE2 . GLU A 1 297  ? 157.496 135.613 176.135 1.00 131.36 ? 419  GLU A OE2 1 
ATOM   1511 N N   . VAL A 1 298  ? 154.948 135.825 171.308 1.00 109.56 ? 420  VAL A N   1 
ATOM   1512 C CA  . VAL A 1 298  ? 154.485 134.967 170.178 1.00 98.43  ? 420  VAL A CA  1 
ATOM   1513 C C   . VAL A 1 298  ? 155.682 134.393 169.417 1.00 88.60  ? 420  VAL A C   1 
ATOM   1514 O O   . VAL A 1 298  ? 156.556 135.179 169.016 1.00 89.48  ? 420  VAL A O   1 
ATOM   1515 C CB  . VAL A 1 298  ? 153.567 135.768 169.239 1.00 97.67  ? 420  VAL A CB  1 
ATOM   1516 C CG1 . VAL A 1 298  ? 153.332 135.047 167.928 1.00 88.64  ? 420  VAL A CG1 1 
ATOM   1517 C CG2 . VAL A 1 298  ? 152.247 136.117 169.904 1.00 105.58 ? 420  VAL A CG2 1 
ATOM   1518 N N   . LEU A 1 299  ? 155.695 133.076 169.203 1.00 80.07  ? 421  LEU A N   1 
ATOM   1519 C CA  . LEU A 1 299  ? 156.751 132.420 168.399 1.00 72.18  ? 421  LEU A CA  1 
ATOM   1520 C C   . LEU A 1 299  ? 156.033 131.780 167.216 1.00 74.05  ? 421  LEU A C   1 
ATOM   1521 O O   . LEU A 1 299  ? 155.036 131.099 167.454 1.00 79.85  ? 421  LEU A O   1 
ATOM   1522 C CB  . LEU A 1 299  ? 157.473 131.370 169.244 1.00 66.59  ? 421  LEU A CB  1 
ATOM   1523 C CG  . LEU A 1 299  ? 158.624 131.882 170.099 1.00 67.59  ? 421  LEU A CG  1 
ATOM   1524 C CD1 . LEU A 1 299  ? 159.195 130.755 170.937 1.00 67.23  ? 421  LEU A CD1 1 
ATOM   1525 C CD2 . LEU A 1 299  ? 159.702 132.482 169.217 1.00 72.41  ? 421  LEU A CD2 1 
ATOM   1526 N N   . TYR A 1 300  ? 156.518 131.988 165.999 1.00 71.08  ? 422  TYR A N   1 
ATOM   1527 C CA  . TYR A 1 300  ? 155.890 131.504 164.780 1.00 64.89  ? 422  TYR A CA  1 
ATOM   1528 C C   . TYR A 1 300  ? 156.569 130.223 164.311 1.00 66.98  ? 422  TYR A C   1 
ATOM   1529 O O   . TYR A 1 300  ? 157.792 130.091 164.386 1.00 72.60  ? 422  TYR A O   1 
ATOM   1530 C CB  . TYR A 1 300  ? 155.955 132.559 163.676 1.00 66.38  ? 422  TYR A CB  1 
ATOM   1531 C CG  . TYR A 1 300  ? 155.137 133.805 163.940 1.00 70.07  ? 422  TYR A CG  1 
ATOM   1532 C CD1 . TYR A 1 300  ? 153.761 133.718 164.173 1.00 69.05  ? 422  TYR A CD1 1 
ATOM   1533 C CD2 . TYR A 1 300  ? 155.737 135.070 163.934 1.00 74.96  ? 422  TYR A CD2 1 
ATOM   1534 C CE1 . TYR A 1 300  ? 152.998 134.863 164.404 1.00 71.57  ? 422  TYR A CE1 1 
ATOM   1535 C CE2 . TYR A 1 300  ? 154.983 136.225 164.166 1.00 78.68  ? 422  TYR A CE2 1 
ATOM   1536 C CZ  . TYR A 1 300  ? 153.618 136.106 164.400 1.00 80.09  ? 422  TYR A CZ  1 
ATOM   1537 O OH  . TYR A 1 300  ? 152.862 137.233 164.630 1.00 86.19  ? 422  TYR A OH  1 
ATOM   1538 N N   . SER A 1 301  ? 155.764 129.277 163.843 1.00 67.39  ? 423  SER A N   1 
ATOM   1539 C CA  . SER A 1 301  ? 156.247 128.025 163.283 1.00 67.12  ? 423  SER A CA  1 
ATOM   1540 C C   . SER A 1 301  ? 156.728 128.257 161.844 1.00 70.00  ? 423  SER A C   1 
ATOM   1541 O O   . SER A 1 301  ? 156.344 129.252 161.222 1.00 70.60  ? 423  SER A O   1 
ATOM   1542 C CB  . SER A 1 301  ? 155.125 126.990 163.349 1.00 69.37  ? 423  SER A CB  1 
ATOM   1543 O OG  . SER A 1 301  ? 155.524 125.699 162.934 1.00 70.89  ? 423  SER A OG  1 
ATOM   1544 N N   . PRO A 1 302  ? 157.610 127.396 161.312 1.00 70.27  ? 424  PRO A N   1 
ATOM   1545 C CA  . PRO A 1 302  ? 158.044 127.543 159.915 1.00 70.20  ? 424  PRO A CA  1 
ATOM   1546 C C   . PRO A 1 302  ? 156.964 127.251 158.880 1.00 74.02  ? 424  PRO A C   1 
ATOM   1547 O O   . PRO A 1 302  ? 155.894 126.718 159.166 1.00 72.92  ? 424  PRO A O   1 
ATOM   1548 C CB  . PRO A 1 302  ? 159.184 126.530 159.793 1.00 68.67  ? 424  PRO A CB  1 
ATOM   1549 C CG  . PRO A 1 302  ? 159.753 126.466 161.126 1.00 71.43  ? 424  PRO A CG  1 
ATOM   1550 C CD  . PRO A 1 302  ? 158.613 126.626 162.075 1.00 71.36  ? 424  PRO A CD  1 
ATOM   1551 N N   . ALA A 1 303  ? 157.272 127.646 157.652 1.00 78.67  ? 425  ALA A N   1 
ATOM   1552 C CA  . ALA A 1 303  ? 156.341 127.629 156.534 1.00 74.82  ? 425  ALA A CA  1 
ATOM   1553 C C   . ALA A 1 303  ? 156.097 126.221 155.999 1.00 76.10  ? 425  ALA A C   1 
ATOM   1554 O O   . ALA A 1 303  ? 156.955 125.339 156.073 1.00 75.92  ? 425  ALA A O   1 
ATOM   1555 C CB  . ALA A 1 303  ? 156.878 128.513 155.409 1.00 81.63  ? 425  ALA A CB  1 
ATOM   1556 N N   . THR A 1 304  ? 154.907 126.035 155.435 1.00 71.64  ? 426  THR A N   1 
ATOM   1557 C CA  . THR A 1 304  ? 154.406 124.773 154.913 1.00 68.15  ? 426  THR A CA  1 
ATOM   1558 C C   . THR A 1 304  ? 154.546 124.808 153.377 1.00 69.30  ? 426  THR A C   1 
ATOM   1559 O O   . THR A 1 304  ? 154.749 125.886 152.811 1.00 69.27  ? 426  THR A O   1 
ATOM   1560 C CB  . THR A 1 304  ? 152.966 124.629 155.432 1.00 58.35  ? 426  THR A CB  1 
ATOM   1561 O OG1 . THR A 1 304  ? 153.021 124.658 156.858 1.00 58.78  ? 426  THR A OG1 1 
ATOM   1562 C CG2 . THR A 1 304  ? 152.313 123.305 155.156 1.00 60.12  ? 426  THR A CG2 1 
ATOM   1563 N N   . PRO A 1 305  ? 154.587 123.652 152.690 1.00 66.11  ? 427  PRO A N   1 
ATOM   1564 C CA  . PRO A 1 305  ? 154.324 123.644 151.249 1.00 64.75  ? 427  PRO A CA  1 
ATOM   1565 C C   . PRO A 1 305  ? 152.930 124.155 150.924 1.00 65.44  ? 427  PRO A C   1 
ATOM   1566 O O   . PRO A 1 305  ? 151.974 123.962 151.680 1.00 72.13  ? 427  PRO A O   1 
ATOM   1567 C CB  . PRO A 1 305  ? 154.446 122.163 150.887 1.00 68.65  ? 427  PRO A CB  1 
ATOM   1568 C CG  . PRO A 1 305  ? 155.499 121.686 151.762 1.00 65.71  ? 427  PRO A CG  1 
ATOM   1569 C CD  . PRO A 1 305  ? 155.327 122.436 153.070 1.00 64.78  ? 427  PRO A CD  1 
ATOM   1570 N N   . ALA A 1 306  ? 152.836 124.826 149.779 1.00 60.76  ? 428  ALA A N   1 
ATOM   1571 C CA  . ALA A 1 306  ? 151.574 125.390 149.328 1.00 59.34  ? 428  ALA A CA  1 
ATOM   1572 C C   . ALA A 1 306  ? 150.648 124.286 148.831 1.00 62.41  ? 428  ALA A C   1 
ATOM   1573 O O   . ALA A 1 306  ? 151.086 123.345 148.162 1.00 68.23  ? 428  ALA A O   1 
ATOM   1574 C CB  . ALA A 1 306  ? 151.823 126.422 148.234 1.00 57.20  ? 428  ALA A CB  1 
ATOM   1575 N N   . TYR A 1 307  ? 149.369 124.392 149.178 1.00 58.65  ? 429  TYR A N   1 
ATOM   1576 C CA  . TYR A 1 307  ? 148.399 123.325 148.986 1.00 59.27  ? 429  TYR A CA  1 
ATOM   1577 C C   . TYR A 1 307  ? 147.354 123.752 147.968 1.00 65.12  ? 429  TYR A C   1 
ATOM   1578 O O   . TYR A 1 307  ? 146.704 124.786 148.141 1.00 66.84  ? 429  TYR A O   1 
ATOM   1579 C CB  . TYR A 1 307  ? 147.737 122.975 150.316 1.00 56.76  ? 429  TYR A CB  1 
ATOM   1580 C CG  . TYR A 1 307  ? 146.515 122.097 150.229 1.00 55.17  ? 429  TYR A CG  1 
ATOM   1581 C CD1 . TYR A 1 307  ? 146.622 120.756 149.848 1.00 55.87  ? 429  TYR A CD1 1 
ATOM   1582 C CD2 . TYR A 1 307  ? 145.254 122.602 150.560 1.00 53.37  ? 429  TYR A CD2 1 
ATOM   1583 C CE1 . TYR A 1 307  ? 145.494 119.939 149.778 1.00 55.42  ? 429  TYR A CE1 1 
ATOM   1584 C CE2 . TYR A 1 307  ? 144.121 121.799 150.497 1.00 57.27  ? 429  TYR A CE2 1 
ATOM   1585 C CZ  . TYR A 1 307  ? 144.253 120.474 150.103 1.00 58.62  ? 429  TYR A CZ  1 
ATOM   1586 O OH  . TYR A 1 307  ? 143.137 119.679 150.040 1.00 59.14  ? 429  TYR A OH  1 
ATOM   1587 N N   . GLN A 1 308  ? 147.189 122.952 146.919 1.00 65.30  ? 430  GLN A N   1 
ATOM   1588 C CA  . GLN A 1 308  ? 146.096 123.124 145.975 1.00 63.53  ? 430  GLN A CA  1 
ATOM   1589 C C   . GLN A 1 308  ? 144.817 122.610 146.619 1.00 64.05  ? 430  GLN A C   1 
ATOM   1590 O O   . GLN A 1 308  ? 144.711 121.416 146.923 1.00 65.85  ? 430  GLN A O   1 
ATOM   1591 C CB  . GLN A 1 308  ? 146.371 122.363 144.678 1.00 69.80  ? 430  GLN A CB  1 
ATOM   1592 C CG  . GLN A 1 308  ? 145.377 122.640 143.553 1.00 66.48  ? 430  GLN A CG  1 
ATOM   1593 C CD  . GLN A 1 308  ? 145.533 124.009 142.939 1.00 69.12  ? 430  GLN A CD  1 
ATOM   1594 O OE1 . GLN A 1 308  ? 144.779 124.927 143.243 1.00 74.08  ? 430  GLN A OE1 1 
ATOM   1595 N NE2 . GLN A 1 308  ? 146.478 124.135 142.020 1.00 70.12  ? 430  GLN A NE2 1 
ATOM   1596 N N   . THR A 1 309  ? 143.863 123.509 146.847 1.00 60.56  ? 431  THR A N   1 
ATOM   1597 C CA  . THR A 1 309  ? 142.523 123.100 147.226 1.00 60.62  ? 431  THR A CA  1 
ATOM   1598 C C   . THR A 1 309  ? 141.838 122.422 146.038 1.00 65.07  ? 431  THR A C   1 
ATOM   1599 O O   . THR A 1 309  ? 142.126 122.759 144.886 1.00 69.48  ? 431  THR A O   1 
ATOM   1600 C CB  . THR A 1 309  ? 141.713 124.311 147.690 1.00 61.11  ? 431  THR A CB  1 
ATOM   1601 O OG1 . THR A 1 309  ? 141.905 125.393 146.772 1.00 73.51  ? 431  THR A OG1 1 
ATOM   1602 C CG2 . THR A 1 309  ? 142.146 124.746 149.074 1.00 53.86  ? 431  THR A CG2 1 
ATOM   1603 N N   . PRO A 1 310  ? 140.981 121.418 146.285 1.00 63.73  ? 432  PRO A N   1 
ATOM   1604 C CA  . PRO A 1 310  ? 140.293 120.763 145.172 1.00 67.88  ? 432  PRO A CA  1 
ATOM   1605 C C   . PRO A 1 310  ? 139.206 121.649 144.594 1.00 75.20  ? 432  PRO A C   1 
ATOM   1606 O O   . PRO A 1 310  ? 138.469 122.318 145.340 1.00 78.35  ? 432  PRO A O   1 
ATOM   1607 C CB  . PRO A 1 310  ? 139.703 119.495 145.817 1.00 66.83  ? 432  PRO A CB  1 
ATOM   1608 C CG  . PRO A 1 310  ? 139.620 119.806 147.257 1.00 66.04  ? 432  PRO A CG  1 
ATOM   1609 C CD  . PRO A 1 310  ? 140.814 120.654 147.536 1.00 65.28  ? 432  PRO A CD  1 
ATOM   1610 N N   . PRO A 1 311  ? 139.081 121.713 143.264 1.00 75.13  ? 433  PRO A N   1 
ATOM   1611 C CA  . PRO A 1 311  ? 138.169 122.692 142.666 1.00 73.65  ? 433  PRO A CA  1 
ATOM   1612 C C   . PRO A 1 311  ? 136.726 122.213 142.631 1.00 76.37  ? 433  PRO A C   1 
ATOM   1613 O O   . PRO A 1 311  ? 136.441 121.033 142.408 1.00 75.80  ? 433  PRO A O   1 
ATOM   1614 C CB  . PRO A 1 311  ? 138.729 122.865 141.250 1.00 70.71  ? 433  PRO A CB  1 
ATOM   1615 C CG  . PRO A 1 311  ? 139.394 121.586 140.941 1.00 69.09  ? 433  PRO A CG  1 
ATOM   1616 C CD  . PRO A 1 311  ? 139.858 120.990 142.236 1.00 70.64  ? 433  PRO A CD  1 
ATOM   1617 N N   . GLU A 1 312  ? 135.814 123.159 142.859 1.00 77.62  ? 434  GLU A N   1 
ATOM   1618 C CA  . GLU A 1 312  ? 134.384 122.917 142.736 1.00 79.96  ? 434  GLU A CA  1 
ATOM   1619 C C   . GLU A 1 312  ? 133.680 124.221 142.390 1.00 81.29  ? 434  GLU A C   1 
ATOM   1620 O O   . GLU A 1 312  ? 134.112 125.305 142.793 1.00 78.61  ? 434  GLU A O   1 
ATOM   1621 C CB  . GLU A 1 312  ? 133.797 122.287 144.020 1.00 81.74  ? 434  GLU A CB  1 
ATOM   1622 C CG  . GLU A 1 312  ? 133.959 123.074 145.326 1.00 85.06  ? 434  GLU A CG  1 
ATOM   1623 C CD  . GLU A 1 312  ? 132.781 123.979 145.652 1.00 88.79  ? 434  GLU A CD  1 
ATOM   1624 O OE1 . GLU A 1 312  ? 131.683 123.747 145.105 1.00 84.02  ? 434  GLU A OE1 1 
ATOM   1625 O OE2 . GLU A 1 312  ? 132.954 124.918 146.457 1.00 91.43  ? 434  GLU A OE2 1 
ATOM   1626 N N   . GLY A 1 313  ? 132.603 124.104 141.617 1.00 80.70  ? 435  GLY A N   1 
ATOM   1627 C CA  . GLY A 1 313  ? 131.669 125.195 141.435 1.00 79.57  ? 435  GLY A CA  1 
ATOM   1628 C C   . GLY A 1 313  ? 132.087 126.239 140.417 1.00 78.95  ? 435  GLY A C   1 
ATOM   1629 O O   . GLY A 1 313  ? 133.122 126.158 139.755 1.00 78.72  ? 435  GLY A O   1 
ATOM   1630 N N   . ALA A 1 314  ? 131.228 127.253 140.312 1.00 76.60  ? 436  ALA A N   1 
ATOM   1631 C CA  . ALA A 1 314  ? 131.406 128.382 139.412 1.00 70.82  ? 436  ALA A CA  1 
ATOM   1632 C C   . ALA A 1 314  ? 132.535 129.284 139.912 1.00 71.10  ? 436  ALA A C   1 
ATOM   1633 O O   . ALA A 1 314  ? 132.879 129.243 141.095 1.00 78.60  ? 436  ALA A O   1 
ATOM   1634 C CB  . ALA A 1 314  ? 130.089 129.159 139.321 1.00 71.02  ? 436  ALA A CB  1 
ATOM   1635 N N   . PRO A 1 315  ? 133.169 130.065 139.023 1.00 65.10  ? 437  PRO A N   1 
ATOM   1636 C CA  . PRO A 1 315  ? 134.094 131.103 139.495 1.00 66.66  ? 437  PRO A CA  1 
ATOM   1637 C C   . PRO A 1 315  ? 133.368 132.216 140.231 1.00 69.25  ? 437  PRO A C   1 
ATOM   1638 O O   . PRO A 1 315  ? 132.200 132.510 139.969 1.00 71.80  ? 437  PRO A O   1 
ATOM   1639 C CB  . PRO A 1 315  ? 134.734 131.628 138.207 1.00 63.53  ? 437  PRO A CB  1 
ATOM   1640 C CG  . PRO A 1 315  ? 134.565 130.558 137.229 1.00 63.36  ? 437  PRO A CG  1 
ATOM   1641 C CD  . PRO A 1 315  ? 133.294 129.876 137.566 1.00 65.29  ? 437  PRO A CD  1 
ATOM   1642 N N   . ILE A 1 316  ? 134.068 132.809 141.193 1.00 68.41  ? 438  ILE A N   1 
ATOM   1643 C CA  . ILE A 1 316  ? 133.501 133.872 142.014 1.00 73.24  ? 438  ILE A CA  1 
ATOM   1644 C C   . ILE A 1 316  ? 134.180 135.209 141.789 1.00 71.64  ? 438  ILE A C   1 
ATOM   1645 O O   . ILE A 1 316  ? 133.766 136.204 142.405 1.00 73.26  ? 438  ILE A O   1 
ATOM   1646 C CB  . ILE A 1 316  ? 133.533 133.508 143.514 1.00 76.77  ? 438  ILE A CB  1 
ATOM   1647 C CG1 . ILE A 1 316  ? 134.973 133.327 143.986 1.00 70.32  ? 438  ILE A CG1 1 
ATOM   1648 C CG2 . ILE A 1 316  ? 132.701 132.260 143.791 1.00 73.90  ? 438  ILE A CG2 1 
ATOM   1649 C CD1 . ILE A 1 316  ? 135.107 133.112 145.473 1.00 69.98  ? 438  ILE A CD1 1 
ATOM   1650 N N   . SER A 1 317  ? 135.198 135.273 140.939 1.00 68.12  ? 439  SER A N   1 
ATOM   1651 C CA  . SER A 1 317  ? 135.882 136.518 140.632 1.00 69.21  ? 439  SER A CA  1 
ATOM   1652 C C   . SER A 1 317  ? 135.759 136.820 139.146 1.00 70.37  ? 439  SER A C   1 
ATOM   1653 O O   . SER A 1 317  ? 135.903 135.928 138.305 1.00 69.26  ? 439  SER A O   1 
ATOM   1654 C CB  . SER A 1 317  ? 137.354 136.456 141.039 1.00 69.34  ? 439  SER A CB  1 
ATOM   1655 O OG  . SER A 1 317  ? 138.038 137.640 140.681 1.00 75.06  ? 439  SER A OG  1 
ATOM   1656 N N   . ALA A 1 318  ? 135.472 138.081 138.840 1.00 68.83  ? 440  ALA A N   1 
ATOM   1657 C CA  . ALA A 1 318  ? 135.375 138.537 137.467 1.00 63.48  ? 440  ALA A CA  1 
ATOM   1658 C C   . ALA A 1 318  ? 136.771 138.639 136.848 1.00 68.12  ? 440  ALA A C   1 
ATOM   1659 O O   . ALA A 1 318  ? 137.759 138.782 137.575 1.00 72.77  ? 440  ALA A O   1 
ATOM   1660 C CB  . ALA A 1 318  ? 134.673 139.894 137.425 1.00 65.98  ? 440  ALA A CB  1 
ATOM   1661 N N   . PRO A 1 319  ? 136.889 138.504 135.520 1.00 64.59  ? 441  PRO A N   1 
ATOM   1662 C CA  . PRO A 1 319  ? 138.169 138.804 134.865 1.00 63.53  ? 441  PRO A CA  1 
ATOM   1663 C C   . PRO A 1 319  ? 138.499 140.286 134.914 1.00 63.32  ? 441  PRO A C   1 
ATOM   1664 O O   . PRO A 1 319  ? 137.619 141.144 134.959 1.00 65.62  ? 441  PRO A O   1 
ATOM   1665 C CB  . PRO A 1 319  ? 137.953 138.334 133.423 1.00 58.58  ? 441  PRO A CB  1 
ATOM   1666 C CG  . PRO A 1 319  ? 136.854 137.368 133.491 1.00 60.54  ? 441  PRO A CG  1 
ATOM   1667 C CD  . PRO A 1 319  ? 135.968 137.808 134.600 1.00 62.10  ? 441  PRO A CD  1 
ATOM   1668 N N   . VAL A 1 320  ? 139.790 140.584 134.925 1.00 60.98  ? 442  VAL A N   1 
ATOM   1669 C CA  . VAL A 1 320  ? 140.267 141.949 135.093 1.00 61.32  ? 442  VAL A CA  1 
ATOM   1670 C C   . VAL A 1 320  ? 140.613 142.507 133.722 1.00 63.15  ? 442  VAL A C   1 
ATOM   1671 O O   . VAL A 1 320  ? 141.568 142.054 133.083 1.00 67.60  ? 442  VAL A O   1 
ATOM   1672 C CB  . VAL A 1 320  ? 141.476 142.007 136.034 1.00 65.05  ? 442  VAL A CB  1 
ATOM   1673 C CG1 . VAL A 1 320  ? 141.769 143.443 136.430 1.00 69.84  ? 442  VAL A CG1 1 
ATOM   1674 C CG2 . VAL A 1 320  ? 141.234 141.146 137.259 1.00 67.37  ? 442  VAL A CG2 1 
ATOM   1675 N N   . ILE A 1 321  ? 139.847 143.497 133.277 1.00 59.68  ? 443  ILE A N   1 
ATOM   1676 C CA  . ILE A 1 321  ? 140.057 144.098 131.966 1.00 58.70  ? 443  ILE A CA  1 
ATOM   1677 C C   . ILE A 1 321  ? 141.183 145.117 132.070 1.00 63.79  ? 443  ILE A C   1 
ATOM   1678 O O   . ILE A 1 321  ? 141.051 146.132 132.762 1.00 70.23  ? 443  ILE A O   1 
ATOM   1679 C CB  . ILE A 1 321  ? 138.770 144.753 131.447 1.00 56.38  ? 443  ILE A CB  1 
ATOM   1680 C CG1 . ILE A 1 321  ? 137.644 143.722 131.367 1.00 56.89  ? 443  ILE A CG1 1 
ATOM   1681 C CG2 . ILE A 1 321  ? 139.024 145.384 130.098 1.00 59.13  ? 443  ILE A CG2 1 
ATOM   1682 C CD1 . ILE A 1 321  ? 136.319 144.277 130.883 1.00 60.00  ? 443  ILE A CD1 1 
ATOM   1683 N N   . GLU A 1 322  ? 142.293 144.852 131.380 1.00 60.91  ? 444  GLU A N   1 
ATOM   1684 C CA  . GLU A 1 322  ? 143.417 145.779 131.418 1.00 63.82  ? 444  GLU A CA  1 
ATOM   1685 C C   . GLU A 1 322  ? 143.203 146.949 130.469 1.00 66.87  ? 444  GLU A C   1 
ATOM   1686 O O   . GLU A 1 322  ? 143.146 148.106 130.898 1.00 71.37  ? 444  GLU A O   1 
ATOM   1687 C CB  . GLU A 1 322  ? 144.718 145.059 131.070 1.00 63.65  ? 444  GLU A CB  1 
ATOM   1688 C CG  . GLU A 1 322  ? 144.861 143.681 131.665 1.00 64.99  ? 444  GLU A CG  1 
ATOM   1689 C CD  . GLU A 1 322  ? 146.021 142.916 131.060 1.00 72.17  ? 444  GLU A CD  1 
ATOM   1690 O OE1 . GLU A 1 322  ? 146.204 142.989 129.828 1.00 74.21  ? 444  GLU A OE1 1 
ATOM   1691 O OE2 . GLU A 1 322  ? 146.760 142.254 131.818 1.00 71.61  ? 444  GLU A OE2 1 
ATOM   1692 N N   . HIS A 1 323  ? 143.085 146.666 129.175 1.00 64.39  ? 445  HIS A N   1 
ATOM   1693 C CA  . HIS A 1 323  ? 142.910 147.704 128.163 1.00 61.63  ? 445  HIS A CA  1 
ATOM   1694 C C   . HIS A 1 323  ? 141.716 147.311 127.304 1.00 58.12  ? 445  HIS A C   1 
ATOM   1695 O O   . HIS A 1 323  ? 141.721 146.254 126.672 1.00 62.42  ? 445  HIS A O   1 
ATOM   1696 C CB  . HIS A 1 323  ? 144.163 147.876 127.315 1.00 62.47  ? 445  HIS A CB  1 
ATOM   1697 C CG  . HIS A 1 323  ? 145.382 148.245 128.098 1.00 69.62  ? 445  HIS A CG  1 
ATOM   1698 N ND1 . HIS A 1 323  ? 146.261 147.306 128.593 1.00 70.04  ? 445  HIS A ND1 1 
ATOM   1699 C CD2 . HIS A 1 323  ? 145.877 149.451 128.461 1.00 73.33  ? 445  HIS A CD2 1 
ATOM   1700 C CE1 . HIS A 1 323  ? 147.241 147.917 129.233 1.00 75.19  ? 445  HIS A CE1 1 
ATOM   1701 N NE2 . HIS A 1 323  ? 147.032 149.221 129.167 1.00 78.71  ? 445  HIS A NE2 1 
ATOM   1702 N N   . LEU A 1 324  ? 140.699 148.162 127.288 1.00 57.92  ? 446  LEU A N   1 
ATOM   1703 C CA  . LEU A 1 324  ? 139.544 148.004 126.417 1.00 57.43  ? 446  LEU A CA  1 
ATOM   1704 C C   . LEU A 1 324  ? 139.426 149.274 125.592 1.00 61.17  ? 446  LEU A C   1 
ATOM   1705 O O   . LEU A 1 324  ? 139.267 150.366 126.150 1.00 64.00  ? 446  LEU A O   1 
ATOM   1706 C CB  . LEU A 1 324  ? 138.280 147.749 127.233 1.00 58.91  ? 446  LEU A CB  1 
ATOM   1707 C CG  . LEU A 1 324  ? 136.927 147.938 126.558 1.00 57.73  ? 446  LEU A CG  1 
ATOM   1708 C CD1 . LEU A 1 324  ? 136.674 146.879 125.514 1.00 58.45  ? 446  LEU A CD1 1 
ATOM   1709 C CD2 . LEU A 1 324  ? 135.840 147.926 127.594 1.00 63.70  ? 446  LEU A CD2 1 
ATOM   1710 N N   . MET A 1 325  ? 139.521 149.139 124.271 1.00 61.30  ? 447  MET A N   1 
ATOM   1711 C CA  . MET A 1 325  ? 139.717 150.309 123.433 1.00 59.44  ? 447  MET A CA  1 
ATOM   1712 C C   . MET A 1 325  ? 139.141 150.076 122.045 1.00 61.06  ? 447  MET A C   1 
ATOM   1713 O O   . MET A 1 325  ? 138.942 148.942 121.610 1.00 64.65  ? 447  MET A O   1 
ATOM   1714 C CB  . MET A 1 325  ? 141.202 150.665 123.370 1.00 61.20  ? 447  MET A CB  1 
ATOM   1715 C CG  . MET A 1 325  ? 142.061 149.618 122.697 1.00 62.42  ? 447  MET A CG  1 
ATOM   1716 S SD  . MET A 1 325  ? 143.770 150.147 122.672 1.00 83.52  ? 447  MET A SD  1 
ATOM   1717 C CE  . MET A 1 325  ? 143.625 151.433 121.450 1.00 69.70  ? 447  MET A CE  1 
ATOM   1718 N N   . GLY A 1 326  ? 138.868 151.179 121.352 1.00 60.58  ? 448  GLY A N   1 
ATOM   1719 C CA  . GLY A 1 326  ? 138.354 151.135 119.998 1.00 62.61  ? 448  GLY A CA  1 
ATOM   1720 C C   . GLY A 1 326  ? 139.454 151.472 119.009 1.00 69.38  ? 448  GLY A C   1 
ATOM   1721 O O   . GLY A 1 326  ? 140.113 152.507 119.125 1.00 73.47  ? 448  GLY A O   1 
ATOM   1722 N N   . LEU A 1 327  ? 139.650 150.579 118.040 1.00 69.63  ? 449  LEU A N   1 
ATOM   1723 C CA  . LEU A 1 327  ? 140.729 150.759 117.078 1.00 66.12  ? 449  LEU A CA  1 
ATOM   1724 C C   . LEU A 1 327  ? 140.340 151.744 115.985 1.00 70.43  ? 449  LEU A C   1 
ATOM   1725 O O   . LEU A 1 327  ? 141.063 152.710 115.725 1.00 76.23  ? 449  LEU A O   1 
ATOM   1726 C CB  . LEU A 1 327  ? 141.119 149.411 116.475 1.00 60.81  ? 449  LEU A CB  1 
ATOM   1727 C CG  . LEU A 1 327  ? 141.580 148.325 117.450 1.00 56.97  ? 449  LEU A CG  1 
ATOM   1728 C CD1 . LEU A 1 327  ? 142.009 147.099 116.682 1.00 55.36  ? 449  LEU A CD1 1 
ATOM   1729 C CD2 . LEU A 1 327  ? 142.705 148.812 118.340 1.00 57.50  ? 449  LEU A CD2 1 
ATOM   1730 N N   . ASP A 1 328  ? 139.204 151.515 115.339 1.00 68.49  ? 450  ASP A N   1 
ATOM   1731 C CA  . ASP A 1 328  ? 138.680 152.416 114.321 1.00 70.49  ? 450  ASP A CA  1 
ATOM   1732 C C   . ASP A 1 328  ? 137.159 152.330 114.380 1.00 75.27  ? 450  ASP A C   1 
ATOM   1733 O O   . ASP A 1 328  ? 136.591 151.928 115.400 1.00 77.40  ? 450  ASP A O   1 
ATOM   1734 C CB  . ASP A 1 328  ? 139.263 152.085 112.936 1.00 70.40  ? 450  ASP A CB  1 
ATOM   1735 C CG  . ASP A 1 328  ? 138.889 150.706 112.460 1.00 72.46  ? 450  ASP A CG  1 
ATOM   1736 O OD1 . ASP A 1 328  ? 137.856 150.568 111.775 1.00 78.07  ? 450  ASP A OD1 1 
ATOM   1737 O OD2 . ASP A 1 328  ? 139.615 149.763 112.786 1.00 70.27  ? 450  ASP A OD2 1 
ATOM   1738 N N   . ASP A 1 329  ? 136.495 152.733 113.292 1.00 76.08  ? 451  ASP A N   1 
ATOM   1739 C CA  . ASP A 1 329  ? 135.038 152.767 113.233 1.00 77.69  ? 451  ASP A CA  1 
ATOM   1740 C C   . ASP A 1 329  ? 134.392 151.384 113.179 1.00 73.79  ? 451  ASP A C   1 
ATOM   1741 O O   . ASP A 1 329  ? 133.198 151.271 113.469 1.00 77.04  ? 451  ASP A O   1 
ATOM   1742 C CB  . ASP A 1 329  ? 134.595 153.581 112.023 1.00 79.75  ? 451  ASP A CB  1 
ATOM   1743 C CG  . ASP A 1 329  ? 135.280 153.146 110.748 1.00 82.54  ? 451  ASP A CG  1 
ATOM   1744 O OD1 . ASP A 1 329  ? 136.486 153.428 110.592 1.00 87.96  ? 451  ASP A OD1 1 
ATOM   1745 O OD2 . ASP A 1 329  ? 134.613 152.525 109.897 1.00 82.60  ? 451  ASP A OD2 1 
ATOM   1746 N N   . SER A 1 330  ? 135.130 150.334 112.813 1.00 68.83  ? 452  SER A N   1 
ATOM   1747 C CA  . SER A 1 330  ? 134.560 148.992 112.753 1.00 67.84  ? 452  SER A CA  1 
ATOM   1748 C C   . SER A 1 330  ? 135.362 147.960 113.534 1.00 67.46  ? 452  SER A C   1 
ATOM   1749 O O   . SER A 1 330  ? 135.207 146.761 113.283 1.00 69.41  ? 452  SER A O   1 
ATOM   1750 C CB  . SER A 1 330  ? 134.419 148.535 111.299 1.00 68.85  ? 452  SER A CB  1 
ATOM   1751 O OG  . SER A 1 330  ? 135.652 148.626 110.613 1.00 69.89  ? 452  SER A OG  1 
ATOM   1752 N N   . HIS A 1 331  ? 136.212 148.380 114.469 1.00 65.30  ? 453  HIS A N   1 
ATOM   1753 C CA  . HIS A 1 331  ? 136.996 147.449 115.268 1.00 61.54  ? 453  HIS A CA  1 
ATOM   1754 C C   . HIS A 1 331  ? 137.027 147.903 116.716 1.00 61.61  ? 453  HIS A C   1 
ATOM   1755 O O   . HIS A 1 331  ? 136.872 149.091 117.009 1.00 68.10  ? 453  HIS A O   1 
ATOM   1756 C CB  . HIS A 1 331  ? 138.422 147.311 114.738 1.00 62.35  ? 453  HIS A CB  1 
ATOM   1757 C CG  . HIS A 1 331  ? 138.516 146.559 113.448 1.00 63.23  ? 453  HIS A CG  1 
ATOM   1758 N ND1 . HIS A 1 331  ? 138.553 147.188 112.222 1.00 65.29  ? 453  HIS A ND1 1 
ATOM   1759 C CD2 . HIS A 1 331  ? 138.575 145.231 113.191 1.00 61.35  ? 453  HIS A CD2 1 
ATOM   1760 C CE1 . HIS A 1 331  ? 138.632 146.280 111.266 1.00 63.47  ? 453  HIS A CE1 1 
ATOM   1761 N NE2 . HIS A 1 331  ? 138.647 145.085 111.828 1.00 61.50  ? 453  HIS A NE2 1 
ATOM   1762 N N   . LEU A 1 332  ? 137.241 146.948 117.618 1.00 56.74  ? 454  LEU A N   1 
ATOM   1763 C CA  . LEU A 1 332  ? 137.173 147.187 119.052 1.00 57.02  ? 454  LEU A CA  1 
ATOM   1764 C C   . LEU A 1 332  ? 138.008 146.127 119.745 1.00 58.76  ? 454  LEU A C   1 
ATOM   1765 O O   . LEU A 1 332  ? 137.745 144.935 119.582 1.00 64.29  ? 454  LEU A O   1 
ATOM   1766 C CB  . LEU A 1 332  ? 135.720 147.128 119.536 1.00 61.66  ? 454  LEU A CB  1 
ATOM   1767 C CG  . LEU A 1 332  ? 135.271 147.637 120.902 1.00 65.77  ? 454  LEU A CG  1 
ATOM   1768 C CD1 . LEU A 1 332  ? 133.923 148.291 120.717 1.00 71.62  ? 454  LEU A CD1 1 
ATOM   1769 C CD2 . LEU A 1 332  ? 135.165 146.514 121.921 1.00 66.76  ? 454  LEU A CD2 1 
ATOM   1770 N N   . ALA A 1 333  ? 138.987 146.553 120.536 1.00 58.19  ? 455  ALA A N   1 
ATOM   1771 C CA  . ALA A 1 333  ? 139.961 145.651 121.130 1.00 53.68  ? 455  ALA A CA  1 
ATOM   1772 C C   . ALA A 1 333  ? 139.782 145.575 122.638 1.00 55.33  ? 455  ALA A C   1 
ATOM   1773 O O   . ALA A 1 333  ? 139.498 146.580 123.291 1.00 62.94  ? 455  ALA A O   1 
ATOM   1774 C CB  . ALA A 1 333  ? 141.381 146.105 120.809 1.00 56.39  ? 455  ALA A CB  1 
ATOM   1775 N N   . VAL A 1 334  ? 139.957 144.380 123.191 1.00 51.98  ? 456  VAL A N   1 
ATOM   1776 C CA  . VAL A 1 334  ? 139.958 144.179 124.634 1.00 52.46  ? 456  VAL A CA  1 
ATOM   1777 C C   . VAL A 1 334  ? 141.148 143.294 124.997 1.00 53.88  ? 456  VAL A C   1 
ATOM   1778 O O   . VAL A 1 334  ? 141.508 142.379 124.251 1.00 60.70  ? 456  VAL A O   1 
ATOM   1779 C CB  . VAL A 1 334  ? 138.590 143.628 125.131 1.00 53.71  ? 456  VAL A CB  1 
ATOM   1780 C CG1 . VAL A 1 334  ? 138.197 142.295 124.506 1.00 54.66  ? 456  VAL A CG1 1 
ATOM   1781 C CG2 . VAL A 1 334  ? 138.499 143.580 126.667 1.00 57.32  ? 456  VAL A CG2 1 
ATOM   1782 N N   . HIS A 1 335  ? 141.843 143.656 126.072 1.00 54.27  ? 457  HIS A N   1 
ATOM   1783 C CA  . HIS A 1 335  ? 142.890 142.840 126.659 1.00 55.88  ? 457  HIS A CA  1 
ATOM   1784 C C   . HIS A 1 335  ? 142.547 142.597 128.118 1.00 58.27  ? 457  HIS A C   1 
ATOM   1785 O O   . HIS A 1 335  ? 142.099 143.509 128.816 1.00 61.31  ? 457  HIS A O   1 
ATOM   1786 C CB  . HIS A 1 335  ? 144.255 143.516 126.542 1.00 56.08  ? 457  HIS A CB  1 
ATOM   1787 C CG  . HIS A 1 335  ? 144.733 143.669 125.134 1.00 54.96  ? 457  HIS A CG  1 
ATOM   1788 N ND1 . HIS A 1 335  ? 145.730 142.885 124.598 1.00 60.06  ? 457  HIS A ND1 1 
ATOM   1789 C CD2 . HIS A 1 335  ? 144.349 144.515 124.150 1.00 53.32  ? 457  HIS A CD2 1 
ATOM   1790 C CE1 . HIS A 1 335  ? 145.941 143.241 123.344 1.00 59.85  ? 457  HIS A CE1 1 
ATOM   1791 N NE2 . HIS A 1 335  ? 145.115 144.228 123.047 1.00 58.08  ? 457  HIS A NE2 1 
ATOM   1792 N N   . TRP A 1 336  ? 142.748 141.367 128.576 1.00 57.48  ? 458  TRP A N   1 
ATOM   1793 C CA  . TRP A 1 336  ? 142.428 141.036 129.953 1.00 56.79  ? 458  TRP A CA  1 
ATOM   1794 C C   . TRP A 1 336  ? 143.417 140.003 130.471 1.00 62.08  ? 458  TRP A C   1 
ATOM   1795 O O   . TRP A 1 336  ? 144.037 139.261 129.706 1.00 66.13  ? 458  TRP A O   1 
ATOM   1796 C CB  . TRP A 1 336  ? 140.985 140.528 130.085 1.00 53.05  ? 458  TRP A CB  1 
ATOM   1797 C CG  . TRP A 1 336  ? 140.716 139.207 129.424 1.00 53.05  ? 458  TRP A CG  1 
ATOM   1798 C CD1 . TRP A 1 336  ? 140.726 137.982 130.020 1.00 56.00  ? 458  TRP A CD1 1 
ATOM   1799 C CD2 . TRP A 1 336  ? 140.377 138.978 128.051 1.00 53.08  ? 458  TRP A CD2 1 
ATOM   1800 N NE1 . TRP A 1 336  ? 140.429 137.008 129.108 1.00 56.28  ? 458  TRP A NE1 1 
ATOM   1801 C CE2 . TRP A 1 336  ? 140.209 137.591 127.890 1.00 53.93  ? 458  TRP A CE2 1 
ATOM   1802 C CE3 . TRP A 1 336  ? 140.205 139.813 126.941 1.00 54.69  ? 458  TRP A CE3 1 
ATOM   1803 C CZ2 . TRP A 1 336  ? 139.877 137.014 126.666 1.00 53.00  ? 458  TRP A CZ2 1 
ATOM   1804 C CZ3 . TRP A 1 336  ? 139.874 139.237 125.721 1.00 52.51  ? 458  TRP A CZ3 1 
ATOM   1805 C CH2 . TRP A 1 336  ? 139.714 137.851 125.597 1.00 51.43  ? 458  TRP A CH2 1 
ATOM   1806 N N   . HIS A 1 337  ? 143.553 139.971 131.790 1.00 63.39  ? 459  HIS A N   1 
ATOM   1807 C CA  . HIS A 1 337  ? 144.231 138.915 132.521 1.00 65.05  ? 459  HIS A CA  1 
ATOM   1808 C C   . HIS A 1 337  ? 143.198 138.368 133.497 1.00 65.18  ? 459  HIS A C   1 
ATOM   1809 O O   . HIS A 1 337  ? 142.244 139.083 133.822 1.00 67.70  ? 459  HIS A O   1 
ATOM   1810 C CB  . HIS A 1 337  ? 145.512 139.437 133.216 1.00 66.81  ? 459  HIS A CB  1 
ATOM   1811 C CG  . HIS A 1 337  ? 145.282 140.260 134.447 1.00 70.55  ? 459  HIS A CG  1 
ATOM   1812 N ND1 . HIS A 1 337  ? 145.217 141.635 134.415 1.00 75.01  ? 459  HIS A ND1 1 
ATOM   1813 C CD2 . HIS A 1 337  ? 145.200 139.912 135.754 1.00 71.18  ? 459  HIS A CD2 1 
ATOM   1814 C CE1 . HIS A 1 337  ? 145.055 142.096 135.642 1.00 75.99  ? 459  HIS A CE1 1 
ATOM   1815 N NE2 . HIS A 1 337  ? 145.035 141.070 136.473 1.00 76.11  ? 459  HIS A NE2 1 
ATOM   1816 N N   . PRO A 1 338  ? 143.294 137.087 133.895 1.00 64.11  ? 460  PRO A N   1 
ATOM   1817 C CA  . PRO A 1 338  ? 142.267 136.521 134.782 1.00 65.77  ? 460  PRO A CA  1 
ATOM   1818 C C   . PRO A 1 338  ? 142.309 137.059 136.206 1.00 72.57  ? 460  PRO A C   1 
ATOM   1819 O O   . PRO A 1 338  ? 143.345 137.493 136.713 1.00 76.97  ? 460  PRO A O   1 
ATOM   1820 C CB  . PRO A 1 338  ? 142.577 135.020 134.773 1.00 65.22  ? 460  PRO A CB  1 
ATOM   1821 C CG  . PRO A 1 338  ? 143.318 134.792 133.560 1.00 64.78  ? 460  PRO A CG  1 
ATOM   1822 C CD  . PRO A 1 338  ? 144.130 136.010 133.329 1.00 64.92  ? 460  PRO A CD  1 
ATOM   1823 N N   . GLY A 1 339  ? 141.147 137.006 136.847 1.00 68.79  ? 461  GLY A N   1 
ATOM   1824 C CA  . GLY A 1 339  ? 141.013 137.365 138.238 1.00 68.87  ? 461  GLY A CA  1 
ATOM   1825 C C   . GLY A 1 339  ? 141.541 136.298 139.178 1.00 76.87  ? 461  GLY A C   1 
ATOM   1826 O O   . GLY A 1 339  ? 142.024 135.240 138.774 1.00 78.43  ? 461  GLY A O   1 
ATOM   1827 N N   . ARG A 1 340  ? 141.413 136.596 140.471 1.00 78.79  ? 462  ARG A N   1 
ATOM   1828 C CA  . ARG A 1 340  ? 142.222 135.917 141.476 1.00 75.46  ? 462  ARG A CA  1 
ATOM   1829 C C   . ARG A 1 340  ? 141.646 134.550 141.836 1.00 74.07  ? 462  ARG A C   1 
ATOM   1830 O O   . ARG A 1 340  ? 142.390 133.571 141.965 1.00 72.34  ? 462  ARG A O   1 
ATOM   1831 C CB  . ARG A 1 340  ? 142.344 136.805 142.711 1.00 76.17  ? 462  ARG A CB  1 
ATOM   1832 C CG  . ARG A 1 340  ? 143.246 136.261 143.790 1.00 82.96  ? 462  ARG A CG  1 
ATOM   1833 C CD  . ARG A 1 340  ? 143.386 137.247 144.929 1.00 90.48  ? 462  ARG A CD  1 
ATOM   1834 N NE  . ARG A 1 340  ? 144.199 136.712 146.014 1.00 100.30 ? 462  ARG A NE  1 
ATOM   1835 C CZ  . ARG A 1 340  ? 145.521 136.806 146.062 1.00 103.47 ? 462  ARG A CZ  1 
ATOM   1836 N NH1 . ARG A 1 340  ? 146.211 137.404 145.104 1.00 100.39 ? 462  ARG A NH1 1 
ATOM   1837 N NH2 . ARG A 1 340  ? 146.170 136.295 147.101 1.00 102.87 ? 462  ARG A NH2 1 
ATOM   1838 N N   . PHE A 1 341  ? 140.327 134.455 141.963 1.00 72.08  ? 463  PHE A N   1 
ATOM   1839 C CA  . PHE A 1 341  ? 139.667 133.221 142.371 1.00 70.12  ? 463  PHE A CA  1 
ATOM   1840 C C   . PHE A 1 341  ? 138.951 132.620 141.168 1.00 69.48  ? 463  PHE A C   1 
ATOM   1841 O O   . PHE A 1 341  ? 137.997 133.200 140.647 1.00 72.80  ? 463  PHE A O   1 
ATOM   1842 C CB  . PHE A 1 341  ? 138.700 133.483 143.520 1.00 71.18  ? 463  PHE A CB  1 
ATOM   1843 C CG  . PHE A 1 341  ? 139.347 134.100 144.722 1.00 73.29  ? 463  PHE A CG  1 
ATOM   1844 C CD1 . PHE A 1 341  ? 140.431 133.473 145.333 1.00 73.52  ? 463  PHE A CD1 1 
ATOM   1845 C CD2 . PHE A 1 341  ? 138.872 135.304 145.245 1.00 73.68  ? 463  PHE A CD2 1 
ATOM   1846 C CE1 . PHE A 1 341  ? 141.042 134.031 146.452 1.00 75.89  ? 463  PHE A CE1 1 
ATOM   1847 C CE2 . PHE A 1 341  ? 139.472 135.878 146.365 1.00 75.50  ? 463  PHE A CE2 1 
ATOM   1848 C CZ  . PHE A 1 341  ? 140.560 135.237 146.967 1.00 78.21  ? 463  PHE A CZ  1 
ATOM   1849 N N   . THR A 1 342  ? 139.393 131.443 140.749 1.00 67.29  ? 464  THR A N   1 
ATOM   1850 C CA  . THR A 1 342  ? 139.010 130.892 139.463 1.00 63.54  ? 464  THR A CA  1 
ATOM   1851 C C   . THR A 1 342  ? 138.170 129.624 139.631 1.00 64.36  ? 464  THR A C   1 
ATOM   1852 O O   . THR A 1 342  ? 137.259 129.383 138.826 1.00 72.64  ? 464  THR A O   1 
ATOM   1853 C CB  . THR A 1 342  ? 140.301 130.657 138.655 1.00 61.15  ? 464  THR A CB  1 
ATOM   1854 O OG1 . THR A 1 342  ? 140.978 131.910 138.520 1.00 68.49  ? 464  THR A OG1 1 
ATOM   1855 C CG2 . THR A 1 342  ? 140.027 130.256 137.245 1.00 61.34  ? 464  THR A CG2 1 
ATOM   1856 N N   . ASN A 1 343  ? 138.400 128.870 140.717 1.00 62.12  ? 465  ASN A N   1 
ATOM   1857 C CA  . ASN A 1 343  ? 137.674 127.679 141.190 1.00 62.90  ? 465  ASN A CA  1 
ATOM   1858 C C   . ASN A 1 343  ? 137.672 126.549 140.166 1.00 64.98  ? 465  ASN A C   1 
ATOM   1859 O O   . ASN A 1 343  ? 136.687 125.816 140.042 1.00 69.10  ? 465  ASN A O   1 
ATOM   1860 C CB  . ASN A 1 343  ? 136.213 127.975 141.622 1.00 64.98  ? 465  ASN A CB  1 
ATOM   1861 C CG  . ASN A 1 343  ? 136.072 128.956 142.816 1.00 69.65  ? 465  ASN A CG  1 
ATOM   1862 O OD1 . ASN A 1 343  ? 134.949 129.257 143.211 1.00 69.69  ? 465  ASN A OD1 1 
ATOM   1863 N ND2 . ASN A 1 343  ? 137.171 129.339 143.461 1.00 73.85  ? 465  ASN A ND2 1 
ATOM   1864 N N   . GLY A 1 344  ? 138.777 126.390 139.444 1.00 63.40  ? 466  GLY A N   1 
ATOM   1865 C CA  . GLY A 1 344  ? 138.916 125.354 138.449 1.00 65.99  ? 466  GLY A CA  1 
ATOM   1866 C C   . GLY A 1 344  ? 139.903 125.769 137.380 1.00 68.61  ? 466  GLY A C   1 
ATOM   1867 O O   . GLY A 1 344  ? 140.329 126.922 137.338 1.00 69.58  ? 466  GLY A O   1 
ATOM   1868 N N   . PRO A 1 345  ? 140.320 124.842 136.519 1.00 67.99  ? 467  PRO A N   1 
ATOM   1869 C CA  . PRO A 1 345  ? 141.076 125.251 135.331 1.00 65.67  ? 467  PRO A CA  1 
ATOM   1870 C C   . PRO A 1 345  ? 140.146 125.914 134.331 1.00 69.37  ? 467  PRO A C   1 
ATOM   1871 O O   . PRO A 1 345  ? 138.969 125.561 134.235 1.00 75.15  ? 467  PRO A O   1 
ATOM   1872 C CB  . PRO A 1 345  ? 141.645 123.932 134.790 1.00 68.69  ? 467  PRO A CB  1 
ATOM   1873 C CG  . PRO A 1 345  ? 141.450 122.933 135.895 1.00 68.90  ? 467  PRO A CG  1 
ATOM   1874 C CD  . PRO A 1 345  ? 140.227 123.379 136.620 1.00 68.30  ? 467  PRO A CD  1 
ATOM   1875 N N   . ILE A 1 346  ? 140.676 126.890 133.599 1.00 65.87  ? 468  ILE A N   1 
ATOM   1876 C CA  . ILE A 1 346  ? 139.866 127.666 132.665 1.00 64.40  ? 468  ILE A CA  1 
ATOM   1877 C C   . ILE A 1 346  ? 139.634 126.843 131.407 1.00 67.66  ? 468  ILE A C   1 
ATOM   1878 O O   . ILE A 1 346  ? 140.586 126.385 130.765 1.00 70.59  ? 468  ILE A O   1 
ATOM   1879 C CB  . ILE A 1 346  ? 140.548 129.002 132.331 1.00 62.66  ? 468  ILE A CB  1 
ATOM   1880 C CG1 . ILE A 1 346  ? 140.693 129.858 133.579 1.00 58.94  ? 468  ILE A CG1 1 
ATOM   1881 C CG2 . ILE A 1 346  ? 139.736 129.789 131.332 1.00 62.54  ? 468  ILE A CG2 1 
ATOM   1882 C CD1 . ILE A 1 346  ? 141.589 131.058 133.398 1.00 61.55  ? 468  ILE A CD1 1 
ATOM   1883 N N   . GLU A 1 347  ? 138.365 126.619 131.072 1.00 64.10  ? 469  GLU A N   1 
ATOM   1884 C CA  . GLU A 1 347  ? 138.007 126.020 129.795 1.00 67.05  ? 469  GLU A CA  1 
ATOM   1885 C C   . GLU A 1 347  ? 137.857 127.047 128.687 1.00 71.88  ? 469  GLU A C   1 
ATOM   1886 O O   . GLU A 1 347  ? 137.975 126.695 127.510 1.00 78.97  ? 469  GLU A O   1 
ATOM   1887 C CB  . GLU A 1 347  ? 136.705 125.225 129.921 1.00 67.78  ? 469  GLU A CB  1 
ATOM   1888 C CG  . GLU A 1 347  ? 136.779 124.074 130.898 1.00 73.83  ? 469  GLU A CG  1 
ATOM   1889 C CD  . GLU A 1 347  ? 138.003 123.207 130.681 1.00 79.92  ? 469  GLU A CD  1 
ATOM   1890 O OE1 . GLU A 1 347  ? 138.108 122.588 129.602 1.00 82.03  ? 469  GLU A OE1 1 
ATOM   1891 O OE2 . GLU A 1 347  ? 138.858 123.143 131.588 1.00 79.38  ? 469  GLU A OE2 1 
ATOM   1892 N N   . GLY A 1 348  ? 137.603 128.299 129.035 1.00 67.45  ? 470  GLY A N   1 
ATOM   1893 C CA  . GLY A 1 348  ? 137.446 129.332 128.031 1.00 62.35  ? 470  GLY A CA  1 
ATOM   1894 C C   . GLY A 1 348  ? 136.881 130.585 128.655 1.00 59.96  ? 470  GLY A C   1 
ATOM   1895 O O   . GLY A 1 348  ? 136.812 130.727 129.878 1.00 60.43  ? 470  GLY A O   1 
ATOM   1896 N N   . TYR A 1 349  ? 136.473 131.499 127.784 1.00 61.10  ? 471  TYR A N   1 
ATOM   1897 C CA  . TYR A 1 349  ? 135.885 132.764 128.181 1.00 57.36  ? 471  TYR A CA  1 
ATOM   1898 C C   . TYR A 1 349  ? 134.576 132.943 127.432 1.00 62.91  ? 471  TYR A C   1 
ATOM   1899 O O   . TYR A 1 349  ? 134.293 132.237 126.464 1.00 66.44  ? 471  TYR A O   1 
ATOM   1900 C CB  . TYR A 1 349  ? 136.830 133.922 127.873 1.00 54.58  ? 471  TYR A CB  1 
ATOM   1901 C CG  . TYR A 1 349  ? 138.085 133.883 128.696 1.00 55.83  ? 471  TYR A CG  1 
ATOM   1902 C CD1 . TYR A 1 349  ? 138.026 133.901 130.091 1.00 57.54  ? 471  TYR A CD1 1 
ATOM   1903 C CD2 . TYR A 1 349  ? 139.330 133.749 128.075 1.00 60.41  ? 471  TYR A CD2 1 
ATOM   1904 C CE1 . TYR A 1 349  ? 139.189 133.847 130.854 1.00 58.26  ? 471  TYR A CE1 1 
ATOM   1905 C CE2 . TYR A 1 349  ? 140.496 133.682 128.822 1.00 60.97  ? 471  TYR A CE2 1 
ATOM   1906 C CZ  . TYR A 1 349  ? 140.412 133.735 130.206 1.00 59.13  ? 471  TYR A CZ  1 
ATOM   1907 O OH  . TYR A 1 349  ? 141.565 133.669 130.939 1.00 61.46  ? 471  TYR A OH  1 
ATOM   1908 N N   . ARG A 1 350  ? 133.768 133.892 127.891 1.00 61.12  ? 472  ARG A N   1 
ATOM   1909 C CA  . ARG A 1 350  ? 132.566 134.285 127.171 1.00 62.95  ? 472  ARG A CA  1 
ATOM   1910 C C   . ARG A 1 350  ? 132.570 135.794 127.023 1.00 65.02  ? 472  ARG A C   1 
ATOM   1911 O O   . ARG A 1 350  ? 132.449 136.519 128.015 1.00 65.25  ? 472  ARG A O   1 
ATOM   1912 C CB  . ARG A 1 350  ? 131.292 133.820 127.877 1.00 63.22  ? 472  ARG A CB  1 
ATOM   1913 C CG  . ARG A 1 350  ? 130.037 134.098 127.066 1.00 65.44  ? 472  ARG A CG  1 
ATOM   1914 C CD  . ARG A 1 350  ? 128.780 133.620 127.768 1.00 71.38  ? 472  ARG A CD  1 
ATOM   1915 N NE  . ARG A 1 350  ? 128.745 132.170 127.923 1.00 75.89  ? 472  ARG A NE  1 
ATOM   1916 C CZ  . ARG A 1 350  ? 128.317 131.323 126.998 1.00 79.20  ? 472  ARG A CZ  1 
ATOM   1917 N NH1 . ARG A 1 350  ? 127.840 131.747 125.839 1.00 79.73  ? 472  ARG A NH1 1 
ATOM   1918 N NH2 . ARG A 1 350  ? 128.360 130.018 127.244 1.00 80.59  ? 472  ARG A NH2 1 
ATOM   1919 N N   . LEU A 1 351  ? 132.716 136.261 125.792 1.00 66.66  ? 473  LEU A N   1 
ATOM   1920 C CA  . LEU A 1 351  ? 132.683 137.679 125.479 1.00 64.51  ? 473  LEU A CA  1 
ATOM   1921 C C   . LEU A 1 351  ? 131.359 137.986 124.804 1.00 71.16  ? 473  LEU A C   1 
ATOM   1922 O O   . LEU A 1 351  ? 131.007 137.349 123.808 1.00 73.71  ? 473  LEU A O   1 
ATOM   1923 C CB  . LEU A 1 351  ? 133.844 138.094 124.571 1.00 63.51  ? 473  LEU A CB  1 
ATOM   1924 C CG  . LEU A 1 351  ? 135.258 138.320 125.118 1.00 62.88  ? 473  LEU A CG  1 
ATOM   1925 C CD1 . LEU A 1 351  ? 136.035 137.042 125.393 1.00 61.68  ? 473  LEU A CD1 1 
ATOM   1926 C CD2 . LEU A 1 351  ? 136.018 139.195 124.163 1.00 62.98  ? 473  LEU A CD2 1 
ATOM   1927 N N   . ARG A 1 352  ? 130.623 138.948 125.354 1.00 75.10  ? 474  ARG A N   1 
ATOM   1928 C CA  . ARG A 1 352  ? 129.346 139.365 124.798 1.00 75.87  ? 474  ARG A CA  1 
ATOM   1929 C C   . ARG A 1 352  ? 129.361 140.865 124.578 1.00 77.93  ? 474  ARG A C   1 
ATOM   1930 O O   . ARG A 1 352  ? 129.336 141.635 125.541 1.00 78.41  ? 474  ARG A O   1 
ATOM   1931 C CB  . ARG A 1 352  ? 128.180 138.984 125.712 1.00 78.48  ? 474  ARG A CB  1 
ATOM   1932 C CG  . ARG A 1 352  ? 126.816 139.301 125.119 1.00 83.79  ? 474  ARG A CG  1 
ATOM   1933 C CD  . ARG A 1 352  ? 125.672 138.881 126.032 1.00 88.52  ? 474  ARG A CD  1 
ATOM   1934 N NE  . ARG A 1 352  ? 125.611 137.438 126.230 1.00 94.71  ? 474  ARG A NE  1 
ATOM   1935 C CZ  . ARG A 1 352  ? 125.848 136.824 127.381 1.00 96.19  ? 474  ARG A CZ  1 
ATOM   1936 N NH1 . ARG A 1 352  ? 126.176 137.502 128.469 1.00 96.41  ? 474  ARG A NH1 1 
ATOM   1937 N NH2 . ARG A 1 352  ? 125.756 135.499 127.442 1.00 92.79  ? 474  ARG A NH2 1 
ATOM   1938 N N   . LEU A 1 353  ? 129.388 141.276 123.316 1.00 81.51  ? 475  LEU A N   1 
ATOM   1939 C CA  . LEU A 1 353  ? 129.323 142.680 122.937 1.00 80.50  ? 475  LEU A CA  1 
ATOM   1940 C C   . LEU A 1 353  ? 127.883 143.017 122.586 1.00 85.33  ? 475  LEU A C   1 
ATOM   1941 O O   . LEU A 1 353  ? 127.302 142.403 121.686 1.00 89.00  ? 475  LEU A O   1 
ATOM   1942 C CB  . LEU A 1 353  ? 130.242 142.979 121.756 1.00 78.27  ? 475  LEU A CB  1 
ATOM   1943 C CG  . LEU A 1 353  ? 130.564 144.455 121.524 1.00 76.57  ? 475  LEU A CG  1 
ATOM   1944 C CD1 . LEU A 1 353  ? 131.425 145.006 122.640 1.00 76.74  ? 475  LEU A CD1 1 
ATOM   1945 C CD2 . LEU A 1 353  ? 131.241 144.632 120.186 1.00 75.06  ? 475  LEU A CD2 1 
ATOM   1946 N N   . SER A 1 354  ? 127.311 143.983 123.296 1.00 86.86  ? 476  SER A N   1 
ATOM   1947 C CA  . SER A 1 354  ? 125.940 144.414 123.074 1.00 91.52  ? 476  SER A CA  1 
ATOM   1948 C C   . SER A 1 354  ? 125.914 145.921 122.868 1.00 91.31  ? 476  SER A C   1 
ATOM   1949 O O   . SER A 1 354  ? 126.658 146.658 123.525 1.00 86.91  ? 476  SER A O   1 
ATOM   1950 C CB  . SER A 1 354  ? 125.040 144.012 124.245 1.00 92.23  ? 476  SER A CB  1 
ATOM   1951 O OG  . SER A 1 354  ? 125.459 144.626 125.450 1.00 91.43  ? 476  SER A OG  1 
ATOM   1952 N N   . SER A 1 355  ? 125.068 146.372 121.947 1.00 92.96  ? 477  SER A N   1 
ATOM   1953 C CA  . SER A 1 355  ? 124.958 147.794 121.664 1.00 97.97  ? 477  SER A CA  1 
ATOM   1954 C C   . SER A 1 355  ? 124.078 148.490 122.694 1.00 105.66 ? 477  SER A C   1 
ATOM   1955 O O   . SER A 1 355  ? 123.195 147.874 123.300 1.00 106.04 ? 477  SER A O   1 
ATOM   1956 C CB  . SER A 1 355  ? 124.387 148.006 120.264 1.00 102.24 ? 477  SER A CB  1 
ATOM   1957 O OG  . SER A 1 355  ? 124.306 149.385 119.959 1.00 103.84 ? 477  SER A OG  1 
ATOM   1958 N N   . SER A 1 356  ? 124.325 149.787 122.891 1.00 109.38 ? 478  SER A N   1 
ATOM   1959 C CA  . SER A 1 356  ? 123.457 150.585 123.754 1.00 111.93 ? 478  SER A CA  1 
ATOM   1960 C C   . SER A 1 356  ? 122.142 150.910 123.059 1.00 111.07 ? 478  SER A C   1 
ATOM   1961 O O   . SER A 1 356  ? 121.079 150.909 123.689 1.00 109.28 ? 478  SER A O   1 
ATOM   1962 C CB  . SER A 1 356  ? 124.172 151.867 124.179 1.00 107.27 ? 478  SER A CB  1 
ATOM   1963 O OG  . SER A 1 356  ? 124.610 152.597 123.048 1.00 105.96 ? 478  SER A OG  1 
ATOM   1964 N N   . GLU A 1 357  ? 122.197 151.198 121.757 1.00 111.23 ? 479  GLU A N   1 
ATOM   1965 C CA  . GLU A 1 357  ? 121.008 151.434 120.941 1.00 111.79 ? 479  GLU A CA  1 
ATOM   1966 C C   . GLU A 1 357  ? 121.030 150.439 119.779 1.00 112.71 ? 479  GLU A C   1 
ATOM   1967 O O   . GLU A 1 357  ? 121.503 150.741 118.681 1.00 113.10 ? 479  GLU A O   1 
ATOM   1968 C CB  . GLU A 1 357  ? 120.953 152.880 120.449 1.00 114.28 ? 479  GLU A CB  1 
ATOM   1969 C CG  . GLU A 1 357  ? 120.694 153.902 121.546 1.00 116.87 ? 479  GLU A CG  1 
ATOM   1970 C CD  . GLU A 1 357  ? 121.972 154.507 122.096 1.00 117.94 ? 479  GLU A CD  1 
ATOM   1971 O OE1 . GLU A 1 357  ? 123.023 154.385 121.432 1.00 118.58 ? 479  GLU A OE1 1 
ATOM   1972 O OE2 . GLU A 1 357  ? 121.925 155.105 123.192 1.00 117.08 ? 479  GLU A OE2 1 
ATOM   1973 N N   . GLY A 1 358  ? 120.506 149.244 120.030 1.00 114.11 ? 480  GLY A N   1 
ATOM   1974 C CA  . GLY A 1 358  ? 120.505 148.192 119.033 1.00 116.33 ? 480  GLY A CA  1 
ATOM   1975 C C   . GLY A 1 358  ? 119.975 146.905 119.621 1.00 117.34 ? 480  GLY A C   1 
ATOM   1976 O O   . GLY A 1 358  ? 119.836 146.767 120.840 1.00 115.06 ? 480  GLY A O   1 
ATOM   1977 N N   . ASN A 1 359  ? 119.681 145.958 118.734 1.00 118.89 ? 481  ASN A N   1 
ATOM   1978 C CA  . ASN A 1 359  ? 119.110 144.677 119.126 1.00 119.39 ? 481  ASN A CA  1 
ATOM   1979 C C   . ASN A 1 359  ? 119.990 143.488 118.766 1.00 118.69 ? 481  ASN A C   1 
ATOM   1980 O O   . ASN A 1 359  ? 119.586 142.346 119.001 1.00 115.53 ? 481  ASN A O   1 
ATOM   1981 C CB  . ASN A 1 359  ? 117.727 144.503 118.490 1.00 116.19 ? 481  ASN A CB  1 
ATOM   1982 N N   . ALA A 1 360  ? 121.174 143.721 118.208 1.00 119.22 ? 482  ALA A N   1 
ATOM   1983 C CA  . ALA A 1 360  ? 122.068 142.651 117.782 1.00 114.79 ? 482  ALA A CA  1 
ATOM   1984 C C   . ALA A 1 360  ? 123.244 142.547 118.743 1.00 110.19 ? 482  ALA A C   1 
ATOM   1985 O O   . ALA A 1 360  ? 124.063 143.469 118.829 1.00 108.19 ? 482  ALA A O   1 
ATOM   1986 C CB  . ALA A 1 360  ? 122.569 142.891 116.357 1.00 111.12 ? 482  ALA A CB  1 
ATOM   1987 N N   . THR A 1 361  ? 123.323 141.427 119.458 1.00 104.27 ? 483  THR A N   1 
ATOM   1988 C CA  . THR A 1 361  ? 124.420 141.143 120.371 1.00 97.01  ? 483  THR A CA  1 
ATOM   1989 C C   . THR A 1 361  ? 125.260 140.005 119.812 1.00 95.23  ? 483  THR A C   1 
ATOM   1990 O O   . THR A 1 361  ? 124.723 139.037 119.264 1.00 95.29  ? 483  THR A O   1 
ATOM   1991 C CB  . THR A 1 361  ? 123.918 140.766 121.773 1.00 97.32  ? 483  THR A CB  1 
ATOM   1992 O OG1 . THR A 1 361  ? 123.477 139.403 121.773 1.00 100.96 ? 483  THR A OG1 1 
ATOM   1993 C CG2 . THR A 1 361  ? 122.772 141.671 122.210 1.00 97.05  ? 483  THR A CG2 1 
ATOM   1994 N N   . SER A 1 362  ? 126.577 140.123 119.952 1.00 91.76  ? 484  SER A N   1 
ATOM   1995 C CA  . SER A 1 362  ? 127.519 139.132 119.447 1.00 89.04  ? 484  SER A CA  1 
ATOM   1996 C C   . SER A 1 362  ? 128.175 138.406 120.610 1.00 86.21  ? 484  SER A C   1 
ATOM   1997 O O   . SER A 1 362  ? 128.801 139.038 121.465 1.00 82.54  ? 484  SER A O   1 
ATOM   1998 C CB  . SER A 1 362  ? 128.585 139.789 118.570 1.00 86.45  ? 484  SER A CB  1 
ATOM   1999 O OG  . SER A 1 362  ? 129.577 138.849 118.193 1.00 87.68  ? 484  SER A OG  1 
ATOM   2000 N N   . GLU A 1 363  ? 128.043 137.083 120.631 1.00 87.69  ? 485  GLU A N   1 
ATOM   2001 C CA  . GLU A 1 363  ? 128.621 136.238 121.668 1.00 81.37  ? 485  GLU A CA  1 
ATOM   2002 C C   . GLU A 1 363  ? 129.736 135.402 121.059 1.00 79.20  ? 485  GLU A C   1 
ATOM   2003 O O   . GLU A 1 363  ? 129.533 134.749 120.030 1.00 81.53  ? 485  GLU A O   1 
ATOM   2004 C CB  . GLU A 1 363  ? 127.563 135.337 122.300 1.00 80.60  ? 485  GLU A CB  1 
ATOM   2005 C CG  . GLU A 1 363  ? 126.549 136.077 123.147 1.00 90.37  ? 485  GLU A CG  1 
ATOM   2006 C CD  . GLU A 1 363  ? 125.498 135.159 123.731 1.00 98.88  ? 485  GLU A CD  1 
ATOM   2007 O OE1 . GLU A 1 363  ? 125.481 133.966 123.368 1.00 102.20 ? 485  GLU A OE1 1 
ATOM   2008 O OE2 . GLU A 1 363  ? 124.687 135.632 124.555 1.00 100.75 ? 485  GLU A OE2 1 
ATOM   2009 N N   . GLN A 1 364  ? 130.905 135.419 121.693 1.00 73.81  ? 486  GLN A N   1 
ATOM   2010 C CA  . GLN A 1 364  ? 132.064 134.687 121.205 1.00 69.75  ? 486  GLN A CA  1 
ATOM   2011 C C   . GLN A 1 364  ? 132.704 133.936 122.361 1.00 68.06  ? 486  GLN A C   1 
ATOM   2012 O O   . GLN A 1 364  ? 132.961 134.523 123.416 1.00 66.97  ? 486  GLN A O   1 
ATOM   2013 C CB  . GLN A 1 364  ? 133.075 135.634 120.555 1.00 68.98  ? 486  GLN A CB  1 
ATOM   2014 C CG  . GLN A 1 364  ? 134.279 134.944 119.949 1.00 70.78  ? 486  GLN A CG  1 
ATOM   2015 C CD  . GLN A 1 364  ? 133.898 134.005 118.824 1.00 73.55  ? 486  GLN A CD  1 
ATOM   2016 O OE1 . GLN A 1 364  ? 133.901 132.787 118.987 1.00 77.18  ? 486  GLN A OE1 1 
ATOM   2017 N NE2 . GLN A 1 364  ? 133.556 134.572 117.675 1.00 70.54  ? 486  GLN A NE2 1 
ATOM   2018 N N   . LEU A 1 365  ? 132.962 132.647 122.162 1.00 68.09  ? 487  LEU A N   1 
ATOM   2019 C CA  . LEU A 1 365  ? 133.638 131.817 123.149 1.00 63.44  ? 487  LEU A CA  1 
ATOM   2020 C C   . LEU A 1 365  ? 135.121 131.761 122.809 1.00 64.48  ? 487  LEU A C   1 
ATOM   2021 O O   . LEU A 1 365  ? 135.515 131.123 121.828 1.00 68.87  ? 487  LEU A O   1 
ATOM   2022 C CB  . LEU A 1 365  ? 133.040 130.413 123.194 1.00 67.16  ? 487  LEU A CB  1 
ATOM   2023 C CG  . LEU A 1 365  ? 131.534 130.333 123.440 1.00 70.85  ? 487  LEU A CG  1 
ATOM   2024 C CD1 . LEU A 1 365  ? 131.057 128.894 123.368 1.00 74.01  ? 487  LEU A CD1 1 
ATOM   2025 C CD2 . LEU A 1 365  ? 131.179 130.953 124.777 1.00 70.35  ? 487  LEU A CD2 1 
ATOM   2026 N N   . VAL A 1 366  ? 135.931 132.420 123.621 1.00 61.47  ? 488  VAL A N   1 
ATOM   2027 C CA  . VAL A 1 366  ? 137.369 132.554 123.407 1.00 61.09  ? 488  VAL A CA  1 
ATOM   2028 C C   . VAL A 1 366  ? 138.068 131.597 124.365 1.00 63.39  ? 488  VAL A C   1 
ATOM   2029 O O   . VAL A 1 366  ? 137.743 131.596 125.557 1.00 69.57  ? 488  VAL A O   1 
ATOM   2030 C CB  . VAL A 1 366  ? 137.831 134.010 123.629 1.00 61.90  ? 488  VAL A CB  1 
ATOM   2031 C CG1 . VAL A 1 366  ? 139.338 134.140 123.692 1.00 62.86  ? 488  VAL A CG1 1 
ATOM   2032 C CG2 . VAL A 1 366  ? 137.292 134.889 122.520 1.00 66.21  ? 488  VAL A CG2 1 
ATOM   2033 N N   . PRO A 1 367  ? 139.017 130.739 123.886 1.00 63.61  ? 489  PRO A N   1 
ATOM   2034 C CA  . PRO A 1 367  ? 139.657 129.748 124.771 1.00 66.12  ? 489  PRO A CA  1 
ATOM   2035 C C   . PRO A 1 367  ? 140.620 130.307 125.815 1.00 68.20  ? 489  PRO A C   1 
ATOM   2036 O O   . PRO A 1 367  ? 140.803 131.523 125.940 1.00 69.26  ? 489  PRO A O   1 
ATOM   2037 C CB  . PRO A 1 367  ? 140.404 128.839 123.786 1.00 63.94  ? 489  PRO A CB  1 
ATOM   2038 C CG  . PRO A 1 367  ? 140.605 129.672 122.581 1.00 65.12  ? 489  PRO A CG  1 
ATOM   2039 C CD  . PRO A 1 367  ? 139.391 130.529 122.478 1.00 65.42  ? 489  PRO A CD  1 
ATOM   2040 N N   . ALA A 1 368  ? 141.247 129.395 126.566 1.00 64.65  ? 490  ALA A N   1 
ATOM   2041 C CA  . ALA A 1 368  ? 141.952 129.757 127.795 1.00 63.69  ? 490  ALA A CA  1 
ATOM   2042 C C   . ALA A 1 368  ? 143.298 130.418 127.536 1.00 65.74  ? 490  ALA A C   1 
ATOM   2043 O O   . ALA A 1 368  ? 143.754 131.222 128.355 1.00 69.02  ? 490  ALA A O   1 
ATOM   2044 C CB  . ALA A 1 368  ? 142.152 128.517 128.659 1.00 67.84  ? 490  ALA A CB  1 
ATOM   2045 N N   . GLY A 1 369  ? 143.953 130.088 126.422 1.00 64.45  ? 491  GLY A N   1 
ATOM   2046 C CA  . GLY A 1 369  ? 145.271 130.635 126.156 1.00 64.05  ? 491  GLY A CA  1 
ATOM   2047 C C   . GLY A 1 369  ? 145.280 132.070 125.679 1.00 66.98  ? 491  GLY A C   1 
ATOM   2048 O O   . GLY A 1 369  ? 146.315 132.736 125.783 1.00 67.80  ? 491  GLY A O   1 
ATOM   2049 N N   . ARG A 1 370  ? 144.158 132.561 125.167 1.00 65.47  ? 492  ARG A N   1 
ATOM   2050 C CA  . ARG A 1 370  ? 144.095 133.895 124.592 1.00 63.37  ? 492  ARG A CA  1 
ATOM   2051 C C   . ARG A 1 370  ? 143.690 134.909 125.650 1.00 60.53  ? 492  ARG A C   1 
ATOM   2052 O O   . ARG A 1 370  ? 142.761 134.669 126.427 1.00 60.10  ? 492  ARG A O   1 
ATOM   2053 C CB  . ARG A 1 370  ? 143.114 133.931 123.422 1.00 63.60  ? 492  ARG A CB  1 
ATOM   2054 C CG  . ARG A 1 370  ? 143.549 133.107 122.231 1.00 67.87  ? 492  ARG A CG  1 
ATOM   2055 C CD  . ARG A 1 370  ? 142.520 133.173 121.125 1.00 70.42  ? 492  ARG A CD  1 
ATOM   2056 N NE  . ARG A 1 370  ? 142.432 134.517 120.570 1.00 70.96  ? 492  ARG A NE  1 
ATOM   2057 C CZ  . ARG A 1 370  ? 141.510 134.909 119.702 1.00 75.25  ? 492  ARG A CZ  1 
ATOM   2058 N NH1 . ARG A 1 370  ? 140.569 134.084 119.273 1.00 74.14  ? 492  ARG A NH1 1 
ATOM   2059 N NH2 . ARG A 1 370  ? 141.535 136.159 119.251 1.00 73.23  ? 492  ARG A NH2 1 
ATOM   2060 N N   . GLY A 1 371  ? 144.390 136.038 125.677 1.00 57.87  ? 493  GLY A N   1 
ATOM   2061 C CA  . GLY A 1 371  ? 144.072 137.113 126.591 1.00 53.32  ? 493  GLY A CA  1 
ATOM   2062 C C   . GLY A 1 371  ? 143.735 138.391 125.858 1.00 53.27  ? 493  GLY A C   1 
ATOM   2063 O O   . GLY A 1 371  ? 143.788 139.480 126.432 1.00 53.44  ? 493  GLY A O   1 
ATOM   2064 N N   . SER A 1 372  ? 143.391 138.264 124.580 1.00 55.35  ? 494  SER A N   1 
ATOM   2065 C CA  . SER A 1 372  ? 143.043 139.414 123.753 1.00 50.60  ? 494  SER A CA  1 
ATOM   2066 C C   . SER A 1 372  ? 142.093 138.962 122.660 1.00 53.88  ? 494  SER A C   1 
ATOM   2067 O O   . SER A 1 372  ? 142.285 137.894 122.075 1.00 62.30  ? 494  SER A O   1 
ATOM   2068 C CB  . SER A 1 372  ? 144.289 140.055 123.143 1.00 54.30  ? 494  SER A CB  1 
ATOM   2069 O OG  . SER A 1 372  ? 144.958 139.153 122.283 1.00 61.27  ? 494  SER A OG  1 
ATOM   2070 N N   . TYR A 1 373  ? 141.070 139.768 122.391 1.00 49.71  ? 495  TYR A N   1 
ATOM   2071 C CA  . TYR A 1 373  ? 140.150 139.529 121.290 1.00 51.84  ? 495  TYR A CA  1 
ATOM   2072 C C   . TYR A 1 373  ? 139.751 140.858 120.672 1.00 55.06  ? 495  TYR A C   1 
ATOM   2073 O O   . TYR A 1 373  ? 139.569 141.850 121.381 1.00 58.51  ? 495  TYR A O   1 
ATOM   2074 C CB  . TYR A 1 373  ? 138.905 138.774 121.750 1.00 53.87  ? 495  TYR A CB  1 
ATOM   2075 C CG  . TYR A 1 373  ? 138.018 138.319 120.618 1.00 56.17  ? 495  TYR A CG  1 
ATOM   2076 C CD1 . TYR A 1 373  ? 138.393 137.245 119.805 1.00 59.42  ? 495  TYR A CD1 1 
ATOM   2077 C CD2 . TYR A 1 373  ? 136.809 138.967 120.356 1.00 57.93  ? 495  TYR A CD2 1 
ATOM   2078 C CE1 . TYR A 1 373  ? 137.580 136.824 118.756 1.00 61.00  ? 495  TYR A CE1 1 
ATOM   2079 C CE2 . TYR A 1 373  ? 135.988 138.559 119.310 1.00 60.16  ? 495  TYR A CE2 1 
ATOM   2080 C CZ  . TYR A 1 373  ? 136.384 137.491 118.519 1.00 60.08  ? 495  TYR A CZ  1 
ATOM   2081 O OH  . TYR A 1 373  ? 135.575 137.082 117.487 1.00 64.12  ? 495  TYR A OH  1 
ATOM   2082 N N   . ILE A 1 374  ? 139.626 140.877 119.349 1.00 55.50  ? 496  ILE A N   1 
ATOM   2083 C CA  . ILE A 1 374  ? 139.237 142.071 118.609 1.00 50.93  ? 496  ILE A CA  1 
ATOM   2084 C C   . ILE A 1 374  ? 137.957 141.760 117.846 1.00 53.27  ? 496  ILE A C   1 
ATOM   2085 O O   . ILE A 1 374  ? 137.930 140.849 117.010 1.00 58.98  ? 496  ILE A O   1 
ATOM   2086 C CB  . ILE A 1 374  ? 140.352 142.548 117.665 1.00 49.56  ? 496  ILE A CB  1 
ATOM   2087 C CG1 . ILE A 1 374  ? 141.533 143.077 118.481 1.00 52.78  ? 496  ILE A CG1 1 
ATOM   2088 C CG2 . ILE A 1 374  ? 139.849 143.636 116.725 1.00 53.34  ? 496  ILE A CG2 1 
ATOM   2089 C CD1 . ILE A 1 374  ? 142.729 143.463 117.663 1.00 52.80  ? 496  ILE A CD1 1 
ATOM   2090 N N   . PHE A 1 375  ? 136.896 142.506 118.144 1.00 55.49  ? 497  PHE A N   1 
ATOM   2091 C CA  . PHE A 1 375  ? 135.638 142.374 117.425 1.00 60.18  ? 497  PHE A CA  1 
ATOM   2092 C C   . PHE A 1 375  ? 135.708 143.131 116.109 1.00 64.31  ? 497  PHE A C   1 
ATOM   2093 O O   . PHE A 1 375  ? 136.193 144.261 116.059 1.00 67.16  ? 497  PHE A O   1 
ATOM   2094 C CB  . PHE A 1 375  ? 134.475 142.913 118.256 1.00 61.16  ? 497  PHE A CB  1 
ATOM   2095 C CG  . PHE A 1 375  ? 134.106 142.054 119.423 1.00 63.06  ? 497  PHE A CG  1 
ATOM   2096 C CD1 . PHE A 1 375  ? 134.706 142.255 120.665 1.00 63.01  ? 497  PHE A CD1 1 
ATOM   2097 C CD2 . PHE A 1 375  ? 133.140 141.056 119.285 1.00 69.07  ? 497  PHE A CD2 1 
ATOM   2098 C CE1 . PHE A 1 375  ? 134.364 141.465 121.754 1.00 66.80  ? 497  PHE A CE1 1 
ATOM   2099 C CE2 . PHE A 1 375  ? 132.784 140.255 120.369 1.00 72.27  ? 497  PHE A CE2 1 
ATOM   2100 C CZ  . PHE A 1 375  ? 133.399 140.463 121.606 1.00 70.91  ? 497  PHE A CZ  1 
ATOM   2101 N N   . SER A 1 376  ? 135.212 142.513 115.047 1.00 65.44  ? 498  SER A N   1 
ATOM   2102 C CA  . SER A 1 376  ? 135.193 143.128 113.732 1.00 66.27  ? 498  SER A CA  1 
ATOM   2103 C C   . SER A 1 376  ? 133.756 143.293 113.264 1.00 70.85  ? 498  SER A C   1 
ATOM   2104 O O   . SER A 1 376  ? 132.817 142.820 113.918 1.00 77.33  ? 498  SER A O   1 
ATOM   2105 C CB  . SER A 1 376  ? 135.991 142.296 112.722 1.00 70.75  ? 498  SER A CB  1 
ATOM   2106 O OG  . SER A 1 376  ? 135.587 140.940 112.747 1.00 74.33  ? 498  SER A OG  1 
ATOM   2107 N N   . GLN A 1 377  ? 133.632 143.988 112.116 1.00 71.42  ? 499  GLN A N   1 
ATOM   2108 C CA  . GLN A 1 377  ? 132.387 144.253 111.369 1.00 74.69  ? 499  GLN A CA  1 
ATOM   2109 C C   . GLN A 1 377  ? 131.346 144.998 112.205 1.00 76.88  ? 499  GLN A C   1 
ATOM   2110 O O   . GLN A 1 377  ? 130.155 144.686 112.169 1.00 80.77  ? 499  GLN A O   1 
ATOM   2111 C CB  . GLN A 1 377  ? 131.796 142.968 110.775 1.00 78.59  ? 499  GLN A CB  1 
ATOM   2112 C CG  . GLN A 1 377  ? 132.682 142.297 109.739 1.00 80.89  ? 499  GLN A CG  1 
ATOM   2113 C CD  . GLN A 1 377  ? 132.853 143.130 108.485 1.00 87.98  ? 499  GLN A CD  1 
ATOM   2114 O OE1 . GLN A 1 377  ? 131.913 143.772 108.018 1.00 91.22  ? 499  GLN A OE1 1 
ATOM   2115 N NE2 . GLN A 1 377  ? 134.061 143.126 107.935 1.00 86.70  ? 499  GLN A NE2 1 
ATOM   2116 N N   . LEU A 1 378  ? 131.800 145.989 112.967 1.00 74.95  ? 500  LEU A N   1 
ATOM   2117 C CA  . LEU A 1 378  ? 130.927 146.755 113.839 1.00 72.49  ? 500  LEU A CA  1 
ATOM   2118 C C   . LEU A 1 378  ? 130.394 147.993 113.124 1.00 75.81  ? 500  LEU A C   1 
ATOM   2119 O O   . LEU A 1 378  ? 130.519 148.150 111.907 1.00 78.01  ? 500  LEU A O   1 
ATOM   2120 C CB  . LEU A 1 378  ? 131.657 147.148 115.119 1.00 68.90  ? 500  LEU A CB  1 
ATOM   2121 C CG  . LEU A 1 378  ? 132.184 146.028 116.011 1.00 69.03  ? 500  LEU A CG  1 
ATOM   2122 C CD1 . LEU A 1 378  ? 132.724 146.623 117.282 1.00 65.75  ? 500  LEU A CD1 1 
ATOM   2123 C CD2 . LEU A 1 378  ? 131.107 145.004 116.321 1.00 70.82  ? 500  LEU A CD2 1 
ATOM   2124 N N   . GLN A 1 379  ? 129.785 148.886 113.898 1.00 78.83  ? 501  GLN A N   1 
ATOM   2125 C CA  . GLN A 1 379  ? 129.203 150.117 113.390 1.00 81.90  ? 501  GLN A CA  1 
ATOM   2126 C C   . GLN A 1 379  ? 129.968 151.317 113.932 1.00 78.68  ? 501  GLN A C   1 
ATOM   2127 O O   . GLN A 1 379  ? 130.618 151.242 114.978 1.00 81.05  ? 501  GLN A O   1 
ATOM   2128 C CB  . GLN A 1 379  ? 127.724 150.227 113.768 1.00 83.08  ? 501  GLN A CB  1 
ATOM   2129 C CG  . GLN A 1 379  ? 126.860 149.098 113.226 1.00 85.79  ? 501  GLN A CG  1 
ATOM   2130 C CD  . GLN A 1 379  ? 126.684 149.162 111.722 1.00 91.92  ? 501  GLN A CD  1 
ATOM   2131 O OE1 . GLN A 1 379  ? 126.732 148.142 111.036 1.00 90.36  ? 501  GLN A OE1 1 
ATOM   2132 N NE2 . GLN A 1 379  ? 126.469 150.366 111.202 1.00 92.22  ? 501  GLN A NE2 1 
ATOM   2133 N N   . ALA A 1 380  ? 129.873 152.428 113.212 1.00 76.97  ? 502  ALA A N   1 
ATOM   2134 C CA  . ALA A 1 380  ? 130.669 153.604 113.513 1.00 80.76  ? 502  ALA A CA  1 
ATOM   2135 C C   . ALA A 1 380  ? 129.995 154.479 114.565 1.00 84.21  ? 502  ALA A C   1 
ATOM   2136 O O   . ALA A 1 380  ? 128.818 154.832 114.456 1.00 89.04  ? 502  ALA A O   1 
ATOM   2137 C CB  . ALA A 1 380  ? 130.908 154.418 112.245 1.00 85.36  ? 502  ALA A CB  1 
ATOM   2138 N N   . GLY A 1 381  ? 130.771 154.838 115.582 1.00 81.13  ? 503  GLY A N   1 
ATOM   2139 C CA  . GLY A 1 381  ? 130.305 155.788 116.589 1.00 79.90  ? 503  GLY A CA  1 
ATOM   2140 C C   . GLY A 1 381  ? 129.306 155.218 117.568 1.00 82.96  ? 503  GLY A C   1 
ATOM   2141 O O   . GLY A 1 381  ? 128.509 155.965 118.151 1.00 87.30  ? 503  GLY A O   1 
ATOM   2142 N N   . THR A 1 382  ? 129.334 153.904 117.772 1.00 83.05  ? 504  THR A N   1 
ATOM   2143 C CA  . THR A 1 382  ? 128.370 153.215 118.620 1.00 84.12  ? 504  THR A CA  1 
ATOM   2144 C C   . THR A 1 382  ? 129.044 152.871 119.937 1.00 82.92  ? 504  THR A C   1 
ATOM   2145 O O   . THR A 1 382  ? 130.141 152.305 119.944 1.00 81.46  ? 504  THR A O   1 
ATOM   2146 C CB  . THR A 1 382  ? 127.841 151.953 117.946 1.00 84.39  ? 504  THR A CB  1 
ATOM   2147 O OG1 . THR A 1 382  ? 127.572 152.226 116.568 1.00 84.06  ? 504  THR A OG1 1 
ATOM   2148 C CG2 . THR A 1 382  ? 126.562 151.512 118.614 1.00 86.94  ? 504  THR A CG2 1 
ATOM   2149 N N   . ASN A 1 383  ? 128.397 153.221 121.043 1.00 85.30  ? 505  ASN A N   1 
ATOM   2150 C CA  . ASN A 1 383  ? 129.064 153.165 122.333 1.00 85.95  ? 505  ASN A CA  1 
ATOM   2151 C C   . ASN A 1 383  ? 128.636 151.895 123.060 1.00 86.97  ? 505  ASN A C   1 
ATOM   2152 O O   . ASN A 1 383  ? 127.498 151.782 123.527 1.00 86.82  ? 505  ASN A O   1 
ATOM   2153 C CB  . ASN A 1 383  ? 128.785 154.471 123.080 1.00 91.33  ? 505  ASN A CB  1 
ATOM   2154 C CG  . ASN A 1 383  ? 129.074 154.429 124.566 1.00 92.79  ? 505  ASN A CG  1 
ATOM   2155 O OD1 . ASN A 1 383  ? 130.238 154.503 124.957 1.00 92.31  ? 505  ASN A OD1 1 
ATOM   2156 N ND2 . ASN A 1 383  ? 128.024 154.470 125.401 1.00 96.18  ? 505  ASN A ND2 1 
ATOM   2157 N N   . TYR A 1 384  ? 129.560 150.931 123.124 1.00 88.41  ? 506  TYR A N   1 
ATOM   2158 C CA  . TYR A 1 384  ? 129.268 149.509 123.256 1.00 84.59  ? 506  TYR A CA  1 
ATOM   2159 C C   . TYR A 1 384  ? 129.427 149.022 124.688 1.00 85.08  ? 506  TYR A C   1 
ATOM   2160 O O   . TYR A 1 384  ? 130.128 149.629 125.502 1.00 82.02  ? 506  TYR A O   1 
ATOM   2161 C CB  . TYR A 1 384  ? 130.190 148.668 122.359 1.00 78.48  ? 506  TYR A CB  1 
ATOM   2162 C CG  . TYR A 1 384  ? 129.688 148.435 120.955 1.00 79.42  ? 506  TYR A CG  1 
ATOM   2163 C CD1 . TYR A 1 384  ? 128.580 147.618 120.720 1.00 84.94  ? 506  TYR A CD1 1 
ATOM   2164 C CD2 . TYR A 1 384  ? 130.330 149.024 119.859 1.00 77.79  ? 506  TYR A CD2 1 
ATOM   2165 C CE1 . TYR A 1 384  ? 128.115 147.392 119.425 1.00 83.35  ? 506  TYR A CE1 1 
ATOM   2166 C CE2 . TYR A 1 384  ? 129.871 148.811 118.557 1.00 77.60  ? 506  TYR A CE2 1 
ATOM   2167 C CZ  . TYR A 1 384  ? 128.765 147.993 118.355 1.00 79.40  ? 506  TYR A CZ  1 
ATOM   2168 O OH  . TYR A 1 384  ? 128.299 147.768 117.083 1.00 79.22  ? 506  TYR A OH  1 
ATOM   2169 N N   . THR A 1 385  ? 128.769 147.902 124.972 1.00 85.77  ? 507  THR A N   1 
ATOM   2170 C CA  . THR A 1 385  ? 128.797 147.253 126.273 1.00 85.42  ? 507  THR A CA  1 
ATOM   2171 C C   . THR A 1 385  ? 129.384 145.858 126.107 1.00 83.27  ? 507  THR A C   1 
ATOM   2172 O O   . THR A 1 385  ? 128.871 145.064 125.314 1.00 83.01  ? 507  THR A O   1 
ATOM   2173 C CB  . THR A 1 385  ? 127.382 147.169 126.850 1.00 88.88  ? 507  THR A CB  1 
ATOM   2174 O OG1 . THR A 1 385  ? 126.842 148.487 126.989 1.00 87.43  ? 507  THR A OG1 1 
ATOM   2175 C CG2 . THR A 1 385  ? 127.398 146.503 128.205 1.00 88.51  ? 507  THR A CG2 1 
ATOM   2176 N N   . LEU A 1 386  ? 130.446 145.552 126.848 1.00 79.37  ? 508  LEU A N   1 
ATOM   2177 C CA  . LEU A 1 386  ? 131.112 144.262 126.736 1.00 77.05  ? 508  LEU A CA  1 
ATOM   2178 C C   . LEU A 1 386  ? 130.974 143.486 128.038 1.00 76.81  ? 508  LEU A C   1 
ATOM   2179 O O   . LEU A 1 386  ? 131.367 143.975 129.101 1.00 74.87  ? 508  LEU A O   1 
ATOM   2180 C CB  . LEU A 1 386  ? 132.584 144.425 126.367 1.00 73.28  ? 508  LEU A CB  1 
ATOM   2181 C CG  . LEU A 1 386  ? 133.312 143.088 126.209 1.00 73.86  ? 508  LEU A CG  1 
ATOM   2182 C CD1 . LEU A 1 386  ? 132.816 142.330 124.993 1.00 73.64  ? 508  LEU A CD1 1 
ATOM   2183 C CD2 . LEU A 1 386  ? 134.778 143.317 126.108 1.00 70.12  ? 508  LEU A CD2 1 
ATOM   2184 N N   . ALA A 1 387  ? 130.428 142.277 127.945 1.00 76.14  ? 509  ALA A N   1 
ATOM   2185 C CA  . ALA A 1 387  ? 130.292 141.366 129.072 1.00 71.28  ? 509  ALA A CA  1 
ATOM   2186 C C   . ALA A 1 387  ? 131.395 140.320 128.992 1.00 68.56  ? 509  ALA A C   1 
ATOM   2187 O O   . ALA A 1 387  ? 131.506 139.613 127.989 1.00 69.54  ? 509  ALA A O   1 
ATOM   2188 C CB  . ALA A 1 387  ? 128.919 140.698 129.051 1.00 71.69  ? 509  ALA A CB  1 
ATOM   2189 N N   . LEU A 1 388  ? 132.200 140.213 130.048 1.00 65.52  ? 510  LEU A N   1 
ATOM   2190 C CA  . LEU A 1 388  ? 133.338 139.301 130.076 1.00 59.55  ? 510  LEU A CA  1 
ATOM   2191 C C   . LEU A 1 388  ? 133.241 138.408 131.304 1.00 61.74  ? 510  LEU A C   1 
ATOM   2192 O O   . LEU A 1 388  ? 133.171 138.908 132.430 1.00 66.55  ? 510  LEU A O   1 
ATOM   2193 C CB  . LEU A 1 388  ? 134.655 140.084 130.083 1.00 60.59  ? 510  LEU A CB  1 
ATOM   2194 C CG  . LEU A 1 388  ? 136.008 139.373 130.000 1.00 61.36  ? 510  LEU A CG  1 
ATOM   2195 C CD1 . LEU A 1 388  ? 136.007 138.245 128.993 1.00 58.40  ? 510  LEU A CD1 1 
ATOM   2196 C CD2 . LEU A 1 388  ? 137.089 140.372 129.659 1.00 59.17  ? 510  LEU A CD2 1 
ATOM   2197 N N   . SER A 1 389  ? 133.260 137.093 131.090 1.00 60.79  ? 511  SER A N   1 
ATOM   2198 C CA  . SER A 1 389  ? 133.147 136.136 132.181 1.00 59.72  ? 511  SER A CA  1 
ATOM   2199 C C   . SER A 1 389  ? 134.012 134.918 131.889 1.00 60.82  ? 511  SER A C   1 
ATOM   2200 O O   . SER A 1 389  ? 134.263 134.595 130.727 1.00 66.11  ? 511  SER A O   1 
ATOM   2201 C CB  . SER A 1 389  ? 131.696 135.696 132.393 1.00 61.19  ? 511  SER A CB  1 
ATOM   2202 O OG  . SER A 1 389  ? 131.131 135.197 131.196 1.00 60.92  ? 511  SER A OG  1 
ATOM   2203 N N   . MET A 1 390  ? 134.456 134.248 132.948 1.00 57.58  ? 512  MET A N   1 
ATOM   2204 C CA  . MET A 1 390  ? 135.195 133.003 132.810 1.00 57.04  ? 512  MET A CA  1 
ATOM   2205 C C   . MET A 1 390  ? 134.253 131.829 132.610 1.00 60.23  ? 512  MET A C   1 
ATOM   2206 O O   . MET A 1 390  ? 133.082 131.873 132.987 1.00 66.39  ? 512  MET A O   1 
ATOM   2207 C CB  . MET A 1 390  ? 136.033 132.715 134.045 1.00 63.57  ? 512  MET A CB  1 
ATOM   2208 C CG  . MET A 1 390  ? 137.195 133.614 134.287 1.00 64.97  ? 512  MET A CG  1 
ATOM   2209 S SD  . MET A 1 390  ? 137.554 133.488 136.037 1.00 79.20  ? 512  MET A SD  1 
ATOM   2210 C CE  . MET A 1 390  ? 139.069 134.395 136.097 1.00 64.02  ? 512  MET A CE  1 
ATOM   2211 N N   . ILE A 1 391  ? 134.782 130.762 132.015 1.00 57.91  ? 513  ILE A N   1 
ATOM   2212 C CA  . ILE A 1 391  ? 134.092 129.483 131.895 1.00 60.56  ? 513  ILE A CA  1 
ATOM   2213 C C   . ILE A 1 391  ? 135.053 128.397 132.364 1.00 65.01  ? 513  ILE A C   1 
ATOM   2214 O O   . ILE A 1 391  ? 136.168 128.287 131.845 1.00 69.57  ? 513  ILE A O   1 
ATOM   2215 C CB  . ILE A 1 391  ? 133.616 129.215 130.447 1.00 61.73  ? 513  ILE A CB  1 
ATOM   2216 C CG1 . ILE A 1 391  ? 132.454 130.135 130.056 1.00 60.68  ? 513  ILE A CG1 1 
ATOM   2217 C CG2 . ILE A 1 391  ? 133.184 127.765 130.247 1.00 63.83  ? 513  ILE A CG2 1 
ATOM   2218 C CD1 . ILE A 1 391  ? 132.084 130.069 128.594 1.00 64.08  ? 513  ILE A CD1 1 
ATOM   2219 N N   . ASN A 1 392  ? 134.633 127.607 133.352 1.00 65.84  ? 514  ASN A N   1 
ATOM   2220 C CA  . ASN A 1 392  ? 135.355 126.401 133.722 1.00 67.63  ? 514  ASN A CA  1 
ATOM   2221 C C   . ASN A 1 392  ? 134.457 125.186 133.465 1.00 70.80  ? 514  ASN A C   1 
ATOM   2222 O O   . ASN A 1 392  ? 133.425 125.298 132.788 1.00 73.72  ? 514  ASN A O   1 
ATOM   2223 C CB  . ASN A 1 392  ? 135.871 126.497 135.168 1.00 66.19  ? 514  ASN A CB  1 
ATOM   2224 C CG  . ASN A 1 392  ? 134.800 126.868 136.183 1.00 73.08  ? 514  ASN A CG  1 
ATOM   2225 O OD1 . ASN A 1 392  ? 133.624 127.019 135.868 1.00 75.59  ? 514  ASN A OD1 1 
ATOM   2226 N ND2 . ASN A 1 392  ? 135.223 127.008 137.432 1.00 73.51  ? 514  ASN A ND2 1 
ATOM   2227 N N   . LYS A 1 393  ? 134.863 124.024 133.984 1.00 69.66  ? 515  LYS A N   1 
ATOM   2228 C CA  . LYS A 1 393  ? 134.097 122.793 133.821 1.00 73.04  ? 515  LYS A CA  1 
ATOM   2229 C C   . LYS A 1 393  ? 132.784 122.777 134.599 1.00 75.47  ? 515  LYS A C   1 
ATOM   2230 O O   . LYS A 1 393  ? 131.887 122.004 134.246 1.00 77.42  ? 515  LYS A O   1 
ATOM   2231 C CB  . LYS A 1 393  ? 134.933 121.589 134.254 1.00 78.19  ? 515  LYS A CB  1 
ATOM   2232 C CG  . LYS A 1 393  ? 136.107 121.278 133.350 1.00 80.24  ? 515  LYS A CG  1 
ATOM   2233 C CD  . LYS A 1 393  ? 136.916 120.118 133.898 1.00 83.57  ? 515  LYS A CD  1 
ATOM   2234 C CE  . LYS A 1 393  ? 136.149 118.812 133.771 1.00 83.98  ? 515  LYS A CE  1 
ATOM   2235 N NZ  . LYS A 1 393  ? 135.980 118.404 132.349 1.00 82.95  ? 515  LYS A NZ  1 
ATOM   2236 N N   . GLN A 1 394  ? 132.644 123.599 135.639 1.00 76.00  ? 516  GLN A N   1 
ATOM   2237 C CA  . GLN A 1 394  ? 131.470 123.543 136.497 1.00 76.96  ? 516  GLN A CA  1 
ATOM   2238 C C   . GLN A 1 394  ? 130.462 124.657 136.245 1.00 76.63  ? 516  GLN A C   1 
ATOM   2239 O O   . GLN A 1 394  ? 129.314 124.529 136.681 1.00 81.25  ? 516  GLN A O   1 
ATOM   2240 C CB  . GLN A 1 394  ? 131.894 123.580 137.968 1.00 76.82  ? 516  GLN A CB  1 
ATOM   2241 C CG  . GLN A 1 394  ? 132.673 122.359 138.425 1.00 78.54  ? 516  GLN A CG  1 
ATOM   2242 C CD  . GLN A 1 394  ? 134.165 122.617 138.499 1.00 80.59  ? 516  GLN A CD  1 
ATOM   2243 O OE1 . GLN A 1 394  ? 134.600 123.708 138.865 1.00 78.68  ? 516  GLN A OE1 1 
ATOM   2244 N NE2 . GLN A 1 394  ? 134.958 121.609 138.157 1.00 79.54  ? 516  GLN A NE2 1 
ATOM   2245 N N   . GLY A 1 395  ? 130.842 125.734 135.570 1.00 71.25  ? 517  GLY A N   1 
ATOM   2246 C CA  . GLY A 1 395  ? 129.891 126.802 135.328 1.00 68.91  ? 517  GLY A CA  1 
ATOM   2247 C C   . GLY A 1 395  ? 130.520 128.010 134.676 1.00 65.82  ? 517  GLY A C   1 
ATOM   2248 O O   . GLY A 1 395  ? 131.527 127.908 133.975 1.00 66.73  ? 517  GLY A O   1 
ATOM   2249 N N   . GLU A 1 396  ? 129.889 129.160 134.900 1.00 62.93  ? 518  GLU A N   1 
ATOM   2250 C CA  . GLU A 1 396  ? 130.319 130.440 134.354 1.00 60.12  ? 518  GLU A CA  1 
ATOM   2251 C C   . GLU A 1 396  ? 130.380 131.450 135.490 1.00 60.27  ? 518  GLU A C   1 
ATOM   2252 O O   . GLU A 1 396  ? 129.466 131.511 136.317 1.00 63.55  ? 518  GLU A O   1 
ATOM   2253 C CB  . GLU A 1 396  ? 129.358 130.913 133.254 1.00 66.00  ? 518  GLU A CB  1 
ATOM   2254 C CG  . GLU A 1 396  ? 129.736 132.229 132.580 1.00 71.55  ? 518  GLU A CG  1 
ATOM   2255 C CD  . GLU A 1 396  ? 128.675 132.735 131.629 1.00 74.51  ? 518  GLU A CD  1 
ATOM   2256 O OE1 . GLU A 1 396  ? 127.690 132.008 131.388 1.00 77.93  ? 518  GLU A OE1 1 
ATOM   2257 O OE2 . GLU A 1 396  ? 128.821 133.873 131.138 1.00 71.02  ? 518  GLU A OE2 1 
ATOM   2258 N N   . GLY A 1 397  ? 131.450 132.243 135.530 1.00 58.07  ? 519  GLY A N   1 
ATOM   2259 C CA  . GLY A 1 397  ? 131.676 133.162 136.620 1.00 64.26  ? 519  GLY A CA  1 
ATOM   2260 C C   . GLY A 1 397  ? 130.929 134.476 136.504 1.00 62.81  ? 519  GLY A C   1 
ATOM   2261 O O   . GLY A 1 397  ? 129.982 134.607 135.722 1.00 62.48  ? 519  GLY A O   1 
ATOM   2262 N N   . PRO A 1 398  ? 131.325 135.472 137.298 1.00 63.94  ? 520  PRO A N   1 
ATOM   2263 C CA  . PRO A 1 398  ? 130.669 136.780 137.229 1.00 62.03  ? 520  PRO A CA  1 
ATOM   2264 C C   . PRO A 1 398  ? 131.110 137.569 136.006 1.00 67.05  ? 520  PRO A C   1 
ATOM   2265 O O   . PRO A 1 398  ? 132.116 137.273 135.361 1.00 67.34  ? 520  PRO A O   1 
ATOM   2266 C CB  . PRO A 1 398  ? 131.122 137.477 138.519 1.00 60.37  ? 520  PRO A CB  1 
ATOM   2267 C CG  . PRO A 1 398  ? 131.773 136.411 139.343 1.00 66.66  ? 520  PRO A CG  1 
ATOM   2268 C CD  . PRO A 1 398  ? 132.348 135.466 138.354 1.00 68.79  ? 520  PRO A CD  1 
ATOM   2269 N N   . VAL A 1 399  ? 130.331 138.601 135.709 1.00 68.57  ? 521  VAL A N   1 
ATOM   2270 C CA  . VAL A 1 399  ? 130.482 139.389 134.493 1.00 62.57  ? 521  VAL A CA  1 
ATOM   2271 C C   . VAL A 1 399  ? 131.184 140.690 134.855 1.00 62.94  ? 521  VAL A C   1 
ATOM   2272 O O   . VAL A 1 399  ? 130.738 141.420 135.748 1.00 64.66  ? 521  VAL A O   1 
ATOM   2273 C CB  . VAL A 1 399  ? 129.115 139.637 133.832 1.00 63.32  ? 521  VAL A CB  1 
ATOM   2274 C CG1 . VAL A 1 399  ? 129.156 140.775 132.827 1.00 66.45  ? 521  VAL A CG1 1 
ATOM   2275 C CG2 . VAL A 1 399  ? 128.624 138.364 133.163 1.00 63.42  ? 521  VAL A CG2 1 
ATOM   2276 N N   . ALA A 1 400  ? 132.303 140.963 134.190 1.00 63.82  ? 522  ALA A N   1 
ATOM   2277 C CA  . ALA A 1 400  ? 132.961 142.258 134.259 1.00 66.95  ? 522  ALA A CA  1 
ATOM   2278 C C   . ALA A 1 400  ? 132.563 143.090 133.053 1.00 71.05  ? 522  ALA A C   1 
ATOM   2279 O O   . ALA A 1 400  ? 132.591 142.609 131.917 1.00 70.59  ? 522  ALA A O   1 
ATOM   2280 C CB  . ALA A 1 400  ? 134.476 142.108 134.304 1.00 60.30  ? 522  ALA A CB  1 
ATOM   2281 N N   . LYS A 1 401  ? 132.198 144.341 133.302 1.00 75.61  ? 523  LYS A N   1 
ATOM   2282 C CA  . LYS A 1 401  ? 131.642 145.193 132.267 1.00 72.85  ? 523  LYS A CA  1 
ATOM   2283 C C   . LYS A 1 401  ? 132.529 146.413 132.077 1.00 75.83  ? 523  LYS A C   1 
ATOM   2284 O O   . LYS A 1 401  ? 133.096 146.955 133.027 1.00 77.14  ? 523  LYS A O   1 
ATOM   2285 C CB  . LYS A 1 401  ? 130.210 145.612 132.614 1.00 69.14  ? 523  LYS A CB  1 
ATOM   2286 C CG  . LYS A 1 401  ? 129.173 144.594 132.177 1.00 70.97  ? 523  LYS A CG  1 
ATOM   2287 C CD  . LYS A 1 401  ? 127.882 145.250 131.743 1.00 75.44  ? 523  LYS A CD  1 
ATOM   2288 C CE  . LYS A 1 401  ? 126.682 144.422 132.167 1.00 81.31  ? 523  LYS A CE  1 
ATOM   2289 N NZ  . LYS A 1 401  ? 125.420 145.208 132.127 1.00 78.74  ? 523  LYS A NZ  1 
ATOM   2290 N N   . GLY A 1 402  ? 132.647 146.829 130.822 1.00 76.08  ? 524  GLY A N   1 
ATOM   2291 C CA  . GLY A 1 402  ? 133.406 148.015 130.481 1.00 75.57  ? 524  GLY A CA  1 
ATOM   2292 C C   . GLY A 1 402  ? 132.731 148.731 129.338 1.00 79.85  ? 524  GLY A C   1 
ATOM   2293 O O   . GLY A 1 402  ? 132.010 148.125 128.538 1.00 80.06  ? 524  GLY A O   1 
ATOM   2294 N N   . PHE A 1 403  ? 132.963 150.038 129.270 1.00 82.57  ? 525  PHE A N   1 
ATOM   2295 C CA  . PHE A 1 403  ? 132.246 150.903 128.343 1.00 83.82  ? 525  PHE A CA  1 
ATOM   2296 C C   . PHE A 1 403  ? 133.252 151.555 127.410 1.00 82.56  ? 525  PHE A C   1 
ATOM   2297 O O   . PHE A 1 403  ? 134.198 152.200 127.875 1.00 83.76  ? 525  PHE A O   1 
ATOM   2298 C CB  . PHE A 1 403  ? 131.451 151.965 129.103 1.00 87.66  ? 525  PHE A CB  1 
ATOM   2299 C CG  . PHE A 1 403  ? 130.136 151.471 129.617 1.00 90.29  ? 525  PHE A CG  1 
ATOM   2300 C CD1 . PHE A 1 403  ? 129.921 151.360 130.992 1.00 89.82  ? 525  PHE A CD1 1 
ATOM   2301 C CD2 . PHE A 1 403  ? 129.129 151.082 128.733 1.00 90.30  ? 525  PHE A CD2 1 
ATOM   2302 C CE1 . PHE A 1 403  ? 128.706 150.887 131.487 1.00 93.98  ? 525  PHE A CE1 1 
ATOM   2303 C CE2 . PHE A 1 403  ? 127.909 150.608 129.212 1.00 91.59  ? 525  PHE A CE2 1 
ATOM   2304 C CZ  . PHE A 1 403  ? 127.700 150.512 130.591 1.00 94.63  ? 525  PHE A CZ  1 
ATOM   2305 N N   . VAL A 1 404  ? 133.061 151.383 126.104 1.00 79.13  ? 526  VAL A N   1 
ATOM   2306 C CA  . VAL A 1 404  ? 133.910 152.014 125.110 1.00 79.11  ? 526  VAL A CA  1 
ATOM   2307 C C   . VAL A 1 404  ? 133.040 152.306 123.882 1.00 82.21  ? 526  VAL A C   1 
ATOM   2308 O O   . VAL A 1 404  ? 132.013 151.665 123.657 1.00 83.64  ? 526  VAL A O   1 
ATOM   2309 C CB  . VAL A 1 404  ? 135.146 151.134 124.772 1.00 76.36  ? 526  VAL A CB  1 
ATOM   2310 C CG1 . VAL A 1 404  ? 134.764 149.827 124.083 1.00 72.24  ? 526  VAL A CG1 1 
ATOM   2311 C CG2 . VAL A 1 404  ? 136.324 151.895 124.117 1.00 72.88  ? 526  VAL A CG2 1 
ATOM   2312 N N   . GLN A 1 405  ? 133.421 153.330 123.121 1.00 82.42  ? 527  GLN A N   1 
ATOM   2313 C CA  . GLN A 1 405  ? 132.803 153.602 121.838 1.00 82.93  ? 527  GLN A CA  1 
ATOM   2314 C C   . GLN A 1 405  ? 133.809 153.337 120.734 1.00 81.77  ? 527  GLN A C   1 
ATOM   2315 O O   . GLN A 1 405  ? 135.020 153.455 120.942 1.00 80.83  ? 527  GLN A O   1 
ATOM   2316 C CB  . GLN A 1 405  ? 132.281 155.046 121.751 1.00 87.70  ? 527  GLN A CB  1 
ATOM   2317 C CG  . GLN A 1 405  ? 133.303 156.120 122.059 1.00 92.34  ? 527  GLN A CG  1 
ATOM   2318 C CD  . GLN A 1 405  ? 132.768 157.521 121.841 1.00 101.25 ? 527  GLN A CD  1 
ATOM   2319 O OE1 . GLN A 1 405  ? 131.624 157.707 121.426 1.00 104.50 ? 527  GLN A OE1 1 
ATOM   2320 N NE2 . GLN A 1 405  ? 133.599 158.518 122.118 1.00 102.46 ? 527  GLN A NE2 1 
ATOM   2321 N N   . THR A 1 406  ? 133.302 152.966 119.563 1.00 80.92  ? 528  THR A N   1 
ATOM   2322 C CA  . THR A 1 406  ? 134.140 152.931 118.378 1.00 78.64  ? 528  THR A CA  1 
ATOM   2323 C C   . THR A 1 406  ? 134.339 154.345 117.845 1.00 82.48  ? 528  THR A C   1 
ATOM   2324 O O   . THR A 1 406  ? 133.667 155.298 118.255 1.00 87.37  ? 528  THR A O   1 
ATOM   2325 C CB  . THR A 1 406  ? 133.526 152.048 117.293 1.00 74.72  ? 528  THR A CB  1 
ATOM   2326 O OG1 . THR A 1 406  ? 132.363 152.687 116.756 1.00 79.16  ? 528  THR A OG1 1 
ATOM   2327 C CG2 . THR A 1 406  ? 133.139 150.700 117.856 1.00 75.02  ? 528  THR A CG2 1 
ATOM   2328 N N   . HIS A 1 407  ? 135.268 154.475 116.906 1.00 80.21  ? 529  HIS A N   1 
ATOM   2329 C CA  . HIS A 1 407  ? 135.584 155.774 116.341 1.00 80.87  ? 529  HIS A CA  1 
ATOM   2330 C C   . HIS A 1 407  ? 134.513 156.201 115.339 1.00 85.13  ? 529  HIS A C   1 
ATOM   2331 O O   . HIS A 1 407  ? 133.654 155.418 114.926 1.00 86.38  ? 529  HIS A O   1 
ATOM   2332 C CB  . HIS A 1 407  ? 136.959 155.749 115.679 1.00 79.73  ? 529  HIS A CB  1 
ATOM   2333 C CG  . HIS A 1 407  ? 138.091 155.619 116.649 1.00 79.23  ? 529  HIS A CG  1 
ATOM   2334 N ND1 . HIS A 1 407  ? 139.392 155.413 116.249 1.00 77.76  ? 529  HIS A ND1 1 
ATOM   2335 C CD2 . HIS A 1 407  ? 138.116 155.666 118.001 1.00 79.99  ? 529  HIS A CD2 1 
ATOM   2336 C CE1 . HIS A 1 407  ? 140.171 155.341 117.312 1.00 79.10  ? 529  HIS A CE1 1 
ATOM   2337 N NE2 . HIS A 1 407  ? 139.420 155.488 118.389 1.00 80.81  ? 529  HIS A NE2 1 
ATOM   2338 N N   . SER A 1 408  ? 134.570 157.476 114.963 1.00 89.77  ? 530  SER A N   1 
ATOM   2339 C CA  . SER A 1 408  ? 133.630 158.041 114.009 1.00 92.29  ? 530  SER A CA  1 
ATOM   2340 C C   . SER A 1 408  ? 133.936 157.552 112.600 1.00 95.66  ? 530  SER A C   1 
ATOM   2341 O O   . SER A 1 408  ? 135.033 157.061 112.316 1.00 97.64  ? 530  SER A O   1 
ATOM   2342 C CB  . SER A 1 408  ? 133.677 159.568 114.053 1.00 93.64  ? 530  SER A CB  1 
ATOM   2343 O OG  . SER A 1 408  ? 133.652 160.038 115.389 1.00 92.64  ? 530  SER A OG  1 
ATOM   2344 N N   . ALA A 1 409  ? 132.940 157.669 111.725 1.00 97.49  ? 531  ALA A N   1 
ATOM   2345 C CA  . ALA A 1 409  ? 133.097 157.229 110.346 1.00 103.58 ? 531  ALA A CA  1 
ATOM   2346 C C   . ALA A 1 409  ? 133.976 158.204 109.578 1.00 109.64 ? 531  ALA A C   1 
ATOM   2347 O O   . ALA A 1 409  ? 133.699 159.405 109.523 1.00 111.14 ? 531  ALA A O   1 
ATOM   2348 C CB  . ALA A 1 409  ? 131.734 157.106 109.666 1.00 104.45 ? 531  ALA A CB  1 
ATOM   2349 N N   . ARG A 1 410  ? 135.066 157.680 109.022 1.00 112.42 ? 532  ARG A N   1 
ATOM   2350 C CA  . ARG A 1 410  ? 135.972 158.503 108.237 1.00 122.35 ? 532  ARG A CA  1 
ATOM   2351 C C   . ARG A 1 410  ? 135.350 158.811 106.880 1.00 130.90 ? 532  ARG A C   1 
ATOM   2352 O O   . ARG A 1 410  ? 134.577 158.013 106.339 1.00 131.63 ? 532  ARG A O   1 
ATOM   2353 C CB  . ARG A 1 410  ? 137.339 157.823 108.112 1.00 121.70 ? 532  ARG A CB  1 
ATOM   2354 C CG  . ARG A 1 410  ? 137.409 156.520 107.328 1.00 121.36 ? 532  ARG A CG  1 
ATOM   2355 C CD  . ARG A 1 410  ? 138.820 155.955 107.431 1.00 120.45 ? 532  ARG A CD  1 
ATOM   2356 N NE  . ARG A 1 410  ? 139.027 154.742 106.650 1.00 121.37 ? 532  ARG A NE  1 
ATOM   2357 C CZ  . ARG A 1 410  ? 138.779 153.514 107.088 1.00 120.58 ? 532  ARG A CZ  1 
ATOM   2358 N NH1 . ARG A 1 410  ? 138.287 153.298 108.298 1.00 111.87 ? 532  ARG A NH1 1 
ATOM   2359 N NH2 . ARG A 1 410  ? 139.045 152.478 106.299 1.00 122.38 ? 532  ARG A NH2 1 
ATOM   2360 N N   . ASN A 1 411  ? 135.647 160.002 106.368 1.00 136.69 ? 533  ASN A N   1 
ATOM   2361 C CA  . ASN A 1 411  ? 134.864 160.579 105.284 1.00 139.09 ? 533  ASN A CA  1 
ATOM   2362 C C   . ASN A 1 411  ? 135.218 159.978 103.925 1.00 143.97 ? 533  ASN A C   1 
ATOM   2363 O O   . ASN A 1 411  ? 136.339 160.124 103.427 1.00 145.32 ? 533  ASN A O   1 
ATOM   2364 C CB  . ASN A 1 411  ? 135.021 162.104 105.284 1.00 140.53 ? 533  ASN A CB  1 
ATOM   2365 C CG  . ASN A 1 411  ? 136.463 162.558 105.480 1.00 142.04 ? 533  ASN A CG  1 
ATOM   2366 O OD1 . ASN A 1 411  ? 137.373 161.747 105.649 1.00 141.49 ? 533  ASN A OD1 1 
ATOM   2367 N ND2 . ASN A 1 411  ? 136.671 163.869 105.459 1.00 142.54 ? 533  ASN A ND2 1 
ATOM   2368 N N   . GLU A 1 412  ? 134.253 159.283 103.336 1.00 144.40 ? 534  GLU A N   1 
ATOM   2369 C CA  . GLU A 1 412  ? 134.382 158.752 101.985 1.00 146.49 ? 534  GLU A CA  1 
ATOM   2370 C C   . GLU A 1 412  ? 134.104 159.891 101.017 1.00 146.22 ? 534  GLU A C   1 
ATOM   2371 O O   . GLU A 1 412  ? 132.960 160.121 100.617 1.00 145.26 ? 534  GLU A O   1 
ATOM   2372 C CB  . GLU A 1 412  ? 133.449 157.564 101.769 1.00 147.92 ? 534  GLU A CB  1 
ATOM   2373 C CG  . GLU A 1 412  ? 133.824 156.360 102.618 1.00 149.85 ? 534  GLU A CG  1 
ATOM   2374 C CD  . GLU A 1 412  ? 135.160 155.733 102.223 1.00 151.53 ? 534  GLU A CD  1 
ATOM   2375 O OE1 . GLU A 1 412  ? 135.534 155.753 101.027 1.00 153.18 ? 534  GLU A OE1 1 
ATOM   2376 O OE2 . GLU A 1 412  ? 135.873 155.271 103.133 1.00 149.32 ? 534  GLU A OE2 1 
ATOM   2377 N N   . LYS A 1 413  ? 135.162 160.617 100.676 1.00 145.43 ? 535  LYS A N   1 
ATOM   2378 C CA  . LYS A 1 413  ? 135.070 161.688 99.705  1.00 143.96 ? 535  LYS A CA  1 
ATOM   2379 C C   . LYS A 1 413  ? 134.905 161.093 98.306  1.00 143.01 ? 535  LYS A C   1 
ATOM   2380 O O   . LYS A 1 413  ? 135.476 160.036 98.017  1.00 142.22 ? 535  LYS A O   1 
ATOM   2381 C CB  . LYS A 1 413  ? 136.325 162.558 99.782  1.00 141.89 ? 535  LYS A CB  1 
ATOM   2382 C CG  . LYS A 1 413  ? 136.414 163.363 101.072 1.00 141.94 ? 535  LYS A CG  1 
ATOM   2383 C CD  . LYS A 1 413  ? 137.732 164.111 101.205 1.00 140.63 ? 535  LYS A CD  1 
ATOM   2384 C CE  . LYS A 1 413  ? 137.835 165.265 100.229 1.00 137.42 ? 535  LYS A CE  1 
ATOM   2385 N NZ  . LYS A 1 413  ? 139.077 166.056 100.449 1.00 132.49 ? 535  LYS A NZ  1 
ATOM   2386 N N   . PRO A 1 414  ? 134.114 161.720 97.430  1.00 143.13 ? 536  PRO A N   1 
ATOM   2387 C CA  . PRO A 1 414  ? 133.897 161.143 96.096  1.00 141.75 ? 536  PRO A CA  1 
ATOM   2388 C C   . PRO A 1 414  ? 135.078 161.380 95.165  1.00 139.34 ? 536  PRO A C   1 
ATOM   2389 O O   . PRO A 1 414  ? 136.063 162.036 95.510  1.00 138.60 ? 536  PRO A O   1 
ATOM   2390 C CB  . PRO A 1 414  ? 132.647 161.871 95.592  1.00 141.81 ? 536  PRO A CB  1 
ATOM   2391 C CG  . PRO A 1 414  ? 132.659 163.164 96.310  1.00 142.13 ? 536  PRO A CG  1 
ATOM   2392 C CD  . PRO A 1 414  ? 133.233 162.881 97.666  1.00 142.47 ? 536  PRO A CD  1 
ATOM   2393 N N   . ALA A 1 415  ? 134.947 160.839 93.949  1.00 137.41 ? 537  ALA A N   1 
ATOM   2394 C CA  . ALA A 1 415  ? 136.048 160.868 92.986  1.00 135.41 ? 537  ALA A CA  1 
ATOM   2395 C C   . ALA A 1 415  ? 136.219 162.247 92.359  1.00 137.24 ? 537  ALA A C   1 
ATOM   2396 O O   . ALA A 1 415  ? 137.289 162.562 91.825  1.00 136.16 ? 537  ALA A O   1 
ATOM   2397 C CB  . ALA A 1 415  ? 135.822 159.813 91.904  1.00 132.95 ? 537  ALA A CB  1 
ATOM   2398 N N   . LYS A 1 416  ? 135.172 163.077 92.397  1.00 138.49 ? 538  LYS A N   1 
ATOM   2399 C CA  . LYS A 1 416  ? 135.317 164.474 92.004  1.00 137.63 ? 538  LYS A CA  1 
ATOM   2400 C C   . LYS A 1 416  ? 136.107 165.259 93.046  1.00 137.45 ? 538  LYS A C   1 
ATOM   2401 O O   . LYS A 1 416  ? 136.942 166.102 92.699  1.00 136.52 ? 538  LYS A O   1 
ATOM   2402 C CB  . LYS A 1 416  ? 133.940 165.103 91.790  1.00 138.56 ? 538  LYS A CB  1 
ATOM   2403 C CG  . LYS A 1 416  ? 132.889 164.141 91.259  1.00 140.02 ? 538  LYS A CG  1 
ATOM   2404 C CD  . LYS A 1 416  ? 131.487 164.702 91.430  1.00 140.16 ? 538  LYS A CD  1 
ATOM   2405 C CE  . LYS A 1 416  ? 130.433 163.684 91.024  1.00 140.64 ? 538  LYS A CE  1 
ATOM   2406 N NZ  . LYS A 1 416  ? 129.053 164.180 91.279  1.00 141.98 ? 538  LYS A NZ  1 
ATOM   2407 N N   . ASP A 1 417  ? 135.857 164.995 94.325  1.00 137.34 ? 539  ASP A N   1 
ATOM   2408 C CA  . ASP A 1 417  ? 136.509 165.717 95.418  1.00 136.84 ? 539  ASP A CA  1 
ATOM   2409 C C   . ASP A 1 417  ? 137.626 164.876 96.038  1.00 135.94 ? 539  ASP A C   1 
ATOM   2410 O O   . ASP A 1 417  ? 137.443 164.206 97.050  1.00 137.81 ? 539  ASP A O   1 
ATOM   2411 C CB  . ASP A 1 417  ? 135.481 166.117 96.473  1.00 138.51 ? 539  ASP A CB  1 
ATOM   2412 C CG  . ASP A 1 417  ? 134.292 166.853 95.886  1.00 139.66 ? 539  ASP A CG  1 
ATOM   2413 O OD1 . ASP A 1 417  ? 134.401 167.366 94.754  1.00 142.47 ? 539  ASP A OD1 1 
ATOM   2414 O OD2 . ASP A 1 417  ? 133.242 166.916 96.561  1.00 137.37 ? 539  ASP A OD2 1 
ATOM   2415 N N   . LEU A 1 418  ? 138.801 164.917 95.412  1.00 132.48 ? 540  LEU A N   1 
ATOM   2416 C CA  . LEU A 1 418  ? 140.009 164.293 95.951  1.00 128.08 ? 540  LEU A CA  1 
ATOM   2417 C C   . LEU A 1 418  ? 141.188 165.212 95.663  1.00 124.18 ? 540  LEU A C   1 
ATOM   2418 O O   . LEU A 1 418  ? 141.544 165.425 94.499  1.00 123.77 ? 540  LEU A O   1 
ATOM   2419 C CB  . LEU A 1 418  ? 140.246 162.909 95.349  1.00 126.46 ? 540  LEU A CB  1 
ATOM   2420 C CG  . LEU A 1 418  ? 139.426 161.710 95.826  1.00 128.12 ? 540  LEU A CG  1 
ATOM   2421 C CD1 . LEU A 1 418  ? 139.726 160.492 94.971  1.00 125.50 ? 540  LEU A CD1 1 
ATOM   2422 C CD2 . LEU A 1 418  ? 139.684 161.417 97.292  1.00 127.35 ? 540  LEU A CD2 1 
ATOM   2423 N N   . THR A 1 419  ? 141.793 165.753 96.718  1.00 123.78 ? 541  THR A N   1 
ATOM   2424 C CA  . THR A 1 419  ? 142.918 166.669 96.586  1.00 123.69 ? 541  THR A CA  1 
ATOM   2425 C C   . THR A 1 419  ? 144.247 166.051 96.997  1.00 121.40 ? 541  THR A C   1 
ATOM   2426 O O   . THR A 1 419  ? 145.249 166.769 97.074  1.00 121.65 ? 541  THR A O   1 
ATOM   2427 C CB  . THR A 1 419  ? 142.672 167.936 97.412  1.00 126.65 ? 541  THR A CB  1 
ATOM   2428 O OG1 . THR A 1 419  ? 142.662 167.607 98.806  1.00 127.44 ? 541  THR A OG1 1 
ATOM   2429 C CG2 . THR A 1 419  ? 141.344 168.576 97.034  1.00 125.11 ? 541  THR A CG2 1 
ATOM   2430 N N   . GLU A 1 420  ? 144.289 164.747 97.260  1.00 119.48 ? 542  GLU A N   1 
ATOM   2431 C CA  . GLU A 1 420  ? 145.522 164.114 97.698  1.00 115.46 ? 542  GLU A CA  1 
ATOM   2432 C C   . GLU A 1 420  ? 146.366 163.687 96.499  1.00 113.75 ? 542  GLU A C   1 
ATOM   2433 O O   . GLU A 1 420  ? 146.050 163.977 95.342  1.00 114.97 ? 542  GLU A O   1 
ATOM   2434 C CB  . GLU A 1 420  ? 145.220 162.914 98.592  1.00 113.00 ? 542  GLU A CB  1 
ATOM   2435 C CG  . GLU A 1 420  ? 144.498 163.274 99.874  1.00 117.11 ? 542  GLU A CG  1 
ATOM   2436 C CD  . GLU A 1 420  ? 143.077 162.765 99.902  1.00 120.73 ? 542  GLU A CD  1 
ATOM   2437 O OE1 . GLU A 1 420  ? 142.512 162.537 98.815  1.00 124.44 ? 542  GLU A OE1 1 
ATOM   2438 O OE2 . GLU A 1 420  ? 142.527 162.594 101.009 1.00 119.93 ? 542  GLU A OE2 1 
ATOM   2439 N N   . SER A 1 421  ? 147.461 162.991 96.789  1.00 110.44 ? 543  SER A N   1 
ATOM   2440 C CA  . SER A 1 421  ? 148.381 162.536 95.758  1.00 107.48 ? 543  SER A CA  1 
ATOM   2441 C C   . SER A 1 421  ? 149.069 161.247 96.180  1.00 105.50 ? 543  SER A C   1 
ATOM   2442 O O   . SER A 1 421  ? 149.107 160.893 97.361  1.00 106.21 ? 543  SER A O   1 
ATOM   2443 C CB  . SER A 1 421  ? 149.437 163.588 95.440  1.00 106.56 ? 543  SER A CB  1 
ATOM   2444 O OG  . SER A 1 421  ? 150.133 163.214 94.271  1.00 109.32 ? 543  SER A OG  1 
ATOM   2445 N N   . VAL A 1 422  ? 149.625 160.549 95.189  1.00 102.65 ? 544  VAL A N   1 
ATOM   2446 C CA  . VAL A 1 422  ? 150.318 159.286 95.400  1.00 97.48  ? 544  VAL A CA  1 
ATOM   2447 C C   . VAL A 1 422  ? 151.702 159.352 94.772  1.00 96.89  ? 544  VAL A C   1 
ATOM   2448 O O   . VAL A 1 422  ? 151.959 160.144 93.859  1.00 98.89  ? 544  VAL A O   1 
ATOM   2449 C CB  . VAL A 1 422  ? 149.538 158.080 94.830  1.00 97.53  ? 544  VAL A CB  1 
ATOM   2450 C CG1 . VAL A 1 422  ? 148.353 157.734 95.711  1.00 102.30 ? 544  VAL A CG1 1 
ATOM   2451 C CG2 . VAL A 1 422  ? 149.085 158.360 93.411  1.00 101.64 ? 544  VAL A CG2 1 
ATOM   2452 N N   . LEU A 1 423  ? 152.600 158.509 95.277  1.00 93.67  ? 545  LEU A N   1 
ATOM   2453 C CA  . LEU A 1 423  ? 153.945 158.331 94.743  1.00 90.09  ? 545  LEU A CA  1 
ATOM   2454 C C   . LEU A 1 423  ? 154.048 156.945 94.131  1.00 92.64  ? 545  LEU A C   1 
ATOM   2455 O O   . LEU A 1 423  ? 153.948 155.944 94.846  1.00 97.13  ? 545  LEU A O   1 
ATOM   2456 C CB  . LEU A 1 423  ? 154.992 158.482 95.840  1.00 86.89  ? 545  LEU A CB  1 
ATOM   2457 C CG  . LEU A 1 423  ? 155.537 159.851 96.207  1.00 86.25  ? 545  LEU A CG  1 
ATOM   2458 C CD1 . LEU A 1 423  ? 156.555 159.644 97.296  1.00 82.52  ? 545  LEU A CD1 1 
ATOM   2459 C CD2 . LEU A 1 423  ? 156.164 160.516 95.003  1.00 90.98  ? 545  LEU A CD2 1 
ATOM   2460 N N   . LEU A 1 424  ? 154.266 156.883 92.822  1.00 89.75  ? 546  LEU A N   1 
ATOM   2461 C CA  . LEU A 1 424  ? 154.319 155.617 92.103  1.00 87.55  ? 546  LEU A CA  1 
ATOM   2462 C C   . LEU A 1 424  ? 155.765 155.330 91.729  1.00 89.12  ? 546  LEU A C   1 
ATOM   2463 O O   . LEU A 1 424  ? 156.378 156.085 90.967  1.00 93.20  ? 546  LEU A O   1 
ATOM   2464 C CB  . LEU A 1 424  ? 153.427 155.664 90.867  1.00 85.51  ? 546  LEU A CB  1 
ATOM   2465 C CG  . LEU A 1 424  ? 152.088 156.342 91.150  1.00 89.87  ? 546  LEU A CG  1 
ATOM   2466 C CD1 . LEU A 1 424  ? 151.389 156.680 89.876  1.00 96.13  ? 546  LEU A CD1 1 
ATOM   2467 C CD2 . LEU A 1 424  ? 151.201 155.479 92.018  1.00 88.69  ? 546  LEU A CD2 1 
ATOM   2468 N N   . VAL A 1 425  ? 156.307 154.247 92.278  1.00 85.04  ? 547  VAL A N   1 
ATOM   2469 C CA  . VAL A 1 425  ? 157.737 153.967 92.256  1.00 83.25  ? 547  VAL A CA  1 
ATOM   2470 C C   . VAL A 1 425  ? 157.982 152.716 91.428  1.00 86.94  ? 547  VAL A C   1 
ATOM   2471 O O   . VAL A 1 425  ? 157.388 151.665 91.691  1.00 92.10  ? 547  VAL A O   1 
ATOM   2472 C CB  . VAL A 1 425  ? 158.276 153.793 93.686  1.00 81.93  ? 547  VAL A CB  1 
ATOM   2473 C CG1 . VAL A 1 425  ? 159.756 153.435 93.684  1.00 83.74  ? 547  VAL A CG1 1 
ATOM   2474 C CG2 . VAL A 1 425  ? 158.012 155.040 94.502  1.00 83.81  ? 547  VAL A CG2 1 
ATOM   2475 N N   . GLY A 1 426  ? 158.852 152.824 90.419  1.00 88.65  ? 548  GLY A N   1 
ATOM   2476 C CA  . GLY A 1 426  ? 159.256 151.678 89.638  1.00 91.50  ? 548  GLY A CA  1 
ATOM   2477 C C   . GLY A 1 426  ? 160.655 151.221 90.011  1.00 98.64  ? 548  GLY A C   1 
ATOM   2478 O O   . GLY A 1 426  ? 161.216 151.628 91.034  1.00 101.98 ? 548  GLY A O   1 
ATOM   2479 N N   . ARG A 1 427  ? 161.199 150.336 89.169  1.00 99.90  ? 549  ARG A N   1 
ATOM   2480 C CA  . ARG A 1 427  ? 162.609 149.973 89.271  1.00 103.40 ? 549  ARG A CA  1 
ATOM   2481 C C   . ARG A 1 427  ? 163.519 151.137 88.899  1.00 103.20 ? 549  ARG A C   1 
ATOM   2482 O O   . ARG A 1 427  ? 164.562 151.337 89.525  1.00 104.96 ? 549  ARG A O   1 
ATOM   2483 C CB  . ARG A 1 427  ? 162.914 148.771 88.371  1.00 107.31 ? 549  ARG A CB  1 
ATOM   2484 C CG  . ARG A 1 427  ? 162.258 147.420 88.686  1.00 108.67 ? 549  ARG A CG  1 
ATOM   2485 C CD  . ARG A 1 427  ? 162.704 146.765 89.987  1.00 108.59 ? 549  ARG A CD  1 
ATOM   2486 N NE  . ARG A 1 427  ? 162.005 147.148 91.206  1.00 108.00 ? 549  ARG A NE  1 
ATOM   2487 C CZ  . ARG A 1 427  ? 162.465 146.843 92.411  1.00 106.40 ? 549  ARG A CZ  1 
ATOM   2488 N NH1 . ARG A 1 427  ? 163.628 146.237 92.570  1.00 105.33 ? 549  ARG A NH1 1 
ATOM   2489 N NH2 . ARG A 1 427  ? 161.739 147.144 93.479  1.00 102.00 ? 549  ARG A NH2 1 
ATOM   2490 N N   . ARG A 1 428  ? 163.151 151.915 87.880  1.00 102.22 ? 550  ARG A N   1 
ATOM   2491 C CA  . ARG A 1 428  ? 164.033 152.952 87.359  1.00 104.66 ? 550  ARG A CA  1 
ATOM   2492 C C   . ARG A 1 428  ? 163.407 154.340 87.356  1.00 102.31 ? 550  ARG A C   1 
ATOM   2493 O O   . ARG A 1 428  ? 163.994 155.264 86.782  1.00 104.25 ? 550  ARG A O   1 
ATOM   2494 C CB  . ARG A 1 428  ? 164.491 152.589 85.941  1.00 108.35 ? 550  ARG A CB  1 
ATOM   2495 C CG  . ARG A 1 428  ? 165.390 151.362 85.862  1.00 111.35 ? 550  ARG A CG  1 
ATOM   2496 C CD  . ARG A 1 428  ? 165.674 150.966 84.431  1.00 114.19 ? 550  ARG A CD  1 
ATOM   2497 N NE  . ARG A 1 428  ? 166.446 151.986 83.736  1.00 119.81 ? 550  ARG A NE  1 
ATOM   2498 C CZ  . ARG A 1 428  ? 167.770 152.043 83.713  1.00 120.90 ? 550  ARG A CZ  1 
ATOM   2499 N NH1 . ARG A 1 428  ? 168.514 151.148 84.343  1.00 119.61 ? 550  ARG A NH1 1 
ATOM   2500 N NH2 . ARG A 1 428  ? 168.363 153.025 83.040  1.00 120.79 ? 550  ARG A NH2 1 
ATOM   2501 N N   . ALA A 1 429  ? 162.249 154.524 87.988  1.00 99.34  ? 551  ALA A N   1 
ATOM   2502 C CA  . ALA A 1 429  ? 161.568 155.809 87.948  1.00 98.25  ? 551  ALA A CA  1 
ATOM   2503 C C   . ALA A 1 429  ? 160.727 156.006 89.201  1.00 97.28  ? 551  ALA A C   1 
ATOM   2504 O O   . ALA A 1 429  ? 160.189 155.045 89.755  1.00 99.10  ? 551  ALA A O   1 
ATOM   2505 C CB  . ALA A 1 429  ? 160.676 155.928 86.707  1.00 98.44  ? 551  ALA A CB  1 
ATOM   2506 N N   . VAL A 1 430  ? 160.623 157.261 89.635  1.00 94.45  ? 552  VAL A N   1 
ATOM   2507 C CA  . VAL A 1 430  ? 159.718 157.681 90.701  1.00 91.47  ? 552  VAL A CA  1 
ATOM   2508 C C   . VAL A 1 430  ? 158.759 158.700 90.106  1.00 95.06  ? 552  VAL A C   1 
ATOM   2509 O O   . VAL A 1 430  ? 159.190 159.746 89.608  1.00 99.68  ? 552  VAL A O   1 
ATOM   2510 C CB  . VAL A 1 430  ? 160.481 158.276 91.899  1.00 91.06  ? 552  VAL A CB  1 
ATOM   2511 C CG1 . VAL A 1 430  ? 159.514 158.852 92.921  1.00 87.48  ? 552  VAL A CG1 1 
ATOM   2512 C CG2 . VAL A 1 430  ? 161.358 157.225 92.550  1.00 90.21  ? 552  VAL A CG2 1 
ATOM   2513 N N   . MET A 1 431  ? 157.464 158.403 90.169  1.00 96.53  ? 553  MET A N   1 
ATOM   2514 C CA  . MET A 1 431  ? 156.451 159.187 89.481  1.00 99.17  ? 553  MET A CA  1 
ATOM   2515 C C   . MET A 1 431  ? 155.466 159.759 90.493  1.00 99.10  ? 553  MET A C   1 
ATOM   2516 O O   . MET A 1 431  ? 155.094 159.103 91.468  1.00 99.00  ? 553  MET A O   1 
ATOM   2517 C CB  . MET A 1 431  ? 155.718 158.329 88.437  1.00 100.92 ? 553  MET A CB  1 
ATOM   2518 C CG  . MET A 1 431  ? 154.942 159.107 87.392  1.00 106.76 ? 553  MET A CG  1 
ATOM   2519 S SD  . MET A 1 431  ? 154.258 158.025 86.127  1.00 121.41 ? 553  MET A SD  1 
ATOM   2520 C CE  . MET A 1 431  ? 155.734 157.611 85.205  1.00 115.59 ? 553  MET A CE  1 
ATOM   2521 N N   . TRP A 1 432  ? 155.057 161.002 90.253  1.00 98.97  ? 554  TRP A N   1 
ATOM   2522 C CA  . TRP A 1 432  ? 154.095 161.708 91.091  1.00 100.78 ? 554  TRP A CA  1 
ATOM   2523 C C   . TRP A 1 432  ? 152.795 161.862 90.321  1.00 104.50 ? 554  TRP A C   1 
ATOM   2524 O O   . TRP A 1 432  ? 152.797 162.345 89.184  1.00 107.17 ? 554  TRP A O   1 
ATOM   2525 C CB  . TRP A 1 432  ? 154.641 163.073 91.507  1.00 104.56 ? 554  TRP A CB  1 
ATOM   2526 C CG  . TRP A 1 432  ? 153.762 163.857 92.431  1.00 105.38 ? 554  TRP A CG  1 
ATOM   2527 C CD1 . TRP A 1 432  ? 153.776 163.834 93.793  1.00 105.24 ? 554  TRP A CD1 1 
ATOM   2528 C CD2 . TRP A 1 432  ? 152.784 164.834 92.056  1.00 106.68 ? 554  TRP A CD2 1 
ATOM   2529 N NE1 . TRP A 1 432  ? 152.844 164.711 94.292  1.00 105.46 ? 554  TRP A NE1 1 
ATOM   2530 C CE2 . TRP A 1 432  ? 152.228 165.345 93.247  1.00 106.32 ? 554  TRP A CE2 1 
ATOM   2531 C CE3 . TRP A 1 432  ? 152.318 165.321 90.829  1.00 109.14 ? 554  TRP A CE3 1 
ATOM   2532 C CZ2 . TRP A 1 432  ? 151.218 166.308 93.247  1.00 107.98 ? 554  TRP A CZ2 1 
ATOM   2533 C CZ3 . TRP A 1 432  ? 151.318 166.284 90.828  1.00 110.59 ? 554  TRP A CZ3 1 
ATOM   2534 C CH2 . TRP A 1 432  ? 150.781 166.767 92.031  1.00 109.16 ? 554  TRP A CH2 1 
ATOM   2535 N N   . GLN A 1 433  ? 151.692 161.449 90.936  1.00 104.54 ? 555  GLN A N   1 
ATOM   2536 C CA  . GLN A 1 433  ? 150.370 161.540 90.333  1.00 107.57 ? 555  GLN A CA  1 
ATOM   2537 C C   . GLN A 1 433  ? 149.396 162.133 91.337  1.00 108.26 ? 555  GLN A C   1 
ATOM   2538 O O   . GLN A 1 433  ? 149.263 161.621 92.453  1.00 107.66 ? 555  GLN A O   1 
ATOM   2539 C CB  . GLN A 1 433  ? 149.886 160.165 89.869  1.00 106.96 ? 555  GLN A CB  1 
ATOM   2540 C CG  . GLN A 1 433  ? 148.453 160.140 89.373  1.00 107.59 ? 555  GLN A CG  1 
ATOM   2541 C CD  . GLN A 1 433  ? 148.329 160.554 87.924  1.00 113.13 ? 555  GLN A CD  1 
ATOM   2542 O OE1 . GLN A 1 433  ? 148.460 159.732 87.018  1.00 116.31 ? 555  GLN A OE1 1 
ATOM   2543 N NE2 . GLN A 1 433  ? 148.074 161.835 87.695  1.00 114.78 ? 555  GLN A NE2 1 
ATOM   2544 N N   . SER A 1 434  ? 148.727 163.212 90.945  1.00 110.61 ? 556  SER A N   1 
ATOM   2545 C CA  . SER A 1 434  ? 147.667 163.776 91.765  1.00 111.01 ? 556  SER A CA  1 
ATOM   2546 C C   . SER A 1 434  ? 146.404 162.945 91.606  1.00 113.61 ? 556  SER A C   1 
ATOM   2547 O O   . SER A 1 434  ? 146.174 162.337 90.557  1.00 115.93 ? 556  SER A O   1 
ATOM   2548 C CB  . SER A 1 434  ? 147.398 165.228 91.372  1.00 111.10 ? 556  SER A CB  1 
ATOM   2549 O OG  . SER A 1 434  ? 146.488 165.838 92.269  1.00 112.02 ? 556  SER A OG  1 
ATOM   2550 N N   . LEU A 1 435  ? 145.574 162.927 92.649  1.00 113.84 ? 557  LEU A N   1 
ATOM   2551 C CA  . LEU A 1 435  ? 144.344 162.149 92.643  1.00 114.11 ? 557  LEU A CA  1 
ATOM   2552 C C   . LEU A 1 435  ? 143.132 162.957 92.189  1.00 117.33 ? 557  LEU A C   1 
ATOM   2553 O O   . LEU A 1 435  ? 141.997 162.587 92.505  1.00 120.31 ? 557  LEU A O   1 
ATOM   2554 C CB  . LEU A 1 435  ? 144.093 161.547 94.026  1.00 112.14 ? 557  LEU A CB  1 
ATOM   2555 C CG  . LEU A 1 435  ? 145.173 160.590 94.533  1.00 107.96 ? 557  LEU A CG  1 
ATOM   2556 C CD1 . LEU A 1 435  ? 144.836 160.095 95.926  1.00 106.59 ? 557  LEU A CD1 1 
ATOM   2557 C CD2 . LEU A 1 435  ? 145.354 159.421 93.580  1.00 106.68 ? 557  LEU A CD2 1 
ATOM   2558 N N   . GLU A 1 436  ? 143.348 164.032 91.433  1.00 119.80 ? 558  GLU A N   1 
ATOM   2559 C CA  . GLU A 1 436  ? 142.281 164.839 90.867  1.00 121.09 ? 558  GLU A CA  1 
ATOM   2560 C C   . GLU A 1 436  ? 141.640 164.104 89.685  1.00 123.69 ? 558  GLU A C   1 
ATOM   2561 O O   . GLU A 1 436  ? 142.209 163.137 89.170  1.00 124.96 ? 558  GLU A O   1 
ATOM   2562 C CB  . GLU A 1 436  ? 142.846 166.199 90.453  1.00 121.10 ? 558  GLU A CB  1 
ATOM   2563 C CG  . GLU A 1 436  ? 143.230 167.076 91.636  1.00 120.90 ? 558  GLU A CG  1 
ATOM   2564 C CD  . GLU A 1 436  ? 144.044 168.288 91.230  1.00 124.75 ? 558  GLU A CD  1 
ATOM   2565 O OE1 . GLU A 1 436  ? 144.430 168.381 90.047  1.00 128.27 ? 558  GLU A OE1 1 
ATOM   2566 O OE2 . GLU A 1 436  ? 144.300 169.148 92.099  1.00 122.04 ? 558  GLU A OE2 1 
ATOM   2567 N N   . PRO A 1 437  ? 140.408 164.492 89.292  1.00 124.75 ? 559  PRO A N   1 
ATOM   2568 C CA  . PRO A 1 437  ? 139.859 164.009 88.004  1.00 124.31 ? 559  PRO A CA  1 
ATOM   2569 C C   . PRO A 1 437  ? 140.664 164.418 86.777  1.00 123.23 ? 559  PRO A C   1 
ATOM   2570 O O   . PRO A 1 437  ? 140.732 163.653 85.806  1.00 123.50 ? 559  PRO A O   1 
ATOM   2571 C CB  . PRO A 1 437  ? 138.453 164.621 87.976  1.00 125.23 ? 559  PRO A CB  1 
ATOM   2572 C CG  . PRO A 1 437  ? 138.081 164.775 89.389  1.00 127.43 ? 559  PRO A CG  1 
ATOM   2573 C CD  . PRO A 1 437  ? 139.338 164.988 90.182  1.00 126.01 ? 559  PRO A CD  1 
ATOM   2574 N N   . ALA A 1 438  ? 141.281 165.591 86.794  1.00 123.71 ? 560  ALA A N   1 
ATOM   2575 C CA  . ALA A 1 438  ? 142.321 165.901 85.830  1.00 125.81 ? 560  ALA A CA  1 
ATOM   2576 C C   . ALA A 1 438  ? 143.680 165.558 86.426  1.00 127.04 ? 560  ALA A C   1 
ATOM   2577 O O   . ALA A 1 438  ? 144.239 166.303 87.235  1.00 127.76 ? 560  ALA A O   1 
ATOM   2578 C CB  . ALA A 1 438  ? 142.271 167.374 85.424  1.00 123.25 ? 560  ALA A CB  1 
ATOM   2579 N N   . GLY A 1 439  ? 144.206 164.414 86.017  1.00 124.40 ? 561  GLY A N   1 
ATOM   2580 C CA  . GLY A 1 439  ? 145.399 163.847 86.626  1.00 122.32 ? 561  GLY A CA  1 
ATOM   2581 C C   . GLY A 1 439  ? 146.660 164.495 86.090  1.00 121.04 ? 561  GLY A C   1 
ATOM   2582 O O   . GLY A 1 439  ? 146.879 164.531 84.878  1.00 121.70 ? 561  GLY A O   1 
ATOM   2583 N N   . GLU A 1 440  ? 147.482 165.005 87.001  1.00 119.06 ? 562  GLU A N   1 
ATOM   2584 C CA  . GLU A 1 440  ? 148.774 165.583 86.662  1.00 120.58 ? 562  GLU A CA  1 
ATOM   2585 C C   . GLU A 1 440  ? 149.868 164.573 86.967  1.00 118.15 ? 562  GLU A C   1 
ATOM   2586 O O   . GLU A 1 440  ? 150.061 164.190 88.125  1.00 115.66 ? 562  GLU A O   1 
ATOM   2587 C CB  . GLU A 1 440  ? 149.018 166.884 87.435  1.00 121.27 ? 562  GLU A CB  1 
ATOM   2588 C CG  . GLU A 1 440  ? 150.340 167.603 87.119  1.00 123.37 ? 562  GLU A CG  1 
ATOM   2589 C CD  . GLU A 1 440  ? 150.462 168.144 85.692  1.00 127.13 ? 562  GLU A CD  1 
ATOM   2590 O OE1 . GLU A 1 440  ? 149.435 168.441 85.039  1.00 126.87 ? 562  GLU A OE1 1 
ATOM   2591 O OE2 . GLU A 1 440  ? 151.609 168.273 85.218  1.00 127.24 ? 562  GLU A OE2 1 
ATOM   2592 N N   . ASN A 1 441  ? 150.580 164.147 85.929  1.00 116.43 ? 563  ASN A N   1 
ATOM   2593 C CA  . ASN A 1 441  ? 151.633 163.150 86.040  1.00 114.65 ? 563  ASN A CA  1 
ATOM   2594 C C   . ASN A 1 441  ? 152.971 163.808 85.751  1.00 113.95 ? 563  ASN A C   1 
ATOM   2595 O O   . ASN A 1 441  ? 153.133 164.463 84.717  1.00 114.44 ? 563  ASN A O   1 
ATOM   2596 C CB  . ASN A 1 441  ? 151.389 161.992 85.069  1.00 115.11 ? 563  ASN A CB  1 
ATOM   2597 C CG  . ASN A 1 441  ? 151.767 160.651 85.655  1.00 114.61 ? 563  ASN A CG  1 
ATOM   2598 O OD1 . ASN A 1 441  ? 151.389 160.321 86.778  1.00 113.89 ? 563  ASN A OD1 1 
ATOM   2599 N ND2 . ASN A 1 441  ? 152.513 159.864 84.891  1.00 115.22 ? 563  ASN A ND2 1 
ATOM   2600 N N   . SER A 1 442  ? 153.926 163.634 86.659  1.00 112.17 ? 564  SER A N   1 
ATOM   2601 C CA  . SER A 1 442  ? 155.242 164.230 86.504  1.00 111.85 ? 564  SER A CA  1 
ATOM   2602 C C   . SER A 1 442  ? 156.309 163.243 86.949  1.00 110.52 ? 564  SER A C   1 
ATOM   2603 O O   . SER A 1 442  ? 156.082 162.410 87.830  1.00 109.30 ? 564  SER A O   1 
ATOM   2604 C CB  . SER A 1 442  ? 155.370 165.532 87.305  1.00 110.92 ? 564  SER A CB  1 
ATOM   2605 O OG  . SER A 1 442  ? 155.189 165.298 88.689  1.00 112.25 ? 564  SER A OG  1 
ATOM   2606 N N   . MET A 1 443  ? 157.479 163.351 86.329  1.00 109.23 ? 565  MET A N   1 
ATOM   2607 C CA  . MET A 1 443  ? 158.631 162.514 86.652  1.00 106.71 ? 565  MET A CA  1 
ATOM   2608 C C   . MET A 1 443  ? 159.491 163.273 87.654  1.00 105.49 ? 565  MET A C   1 
ATOM   2609 O O   . MET A 1 443  ? 160.027 164.339 87.343  1.00 108.31 ? 565  MET A O   1 
ATOM   2610 C CB  . MET A 1 443  ? 159.419 162.171 85.392  1.00 107.34 ? 565  MET A CB  1 
ATOM   2611 C CG  . MET A 1 443  ? 160.564 161.207 85.627  1.00 109.51 ? 565  MET A CG  1 
ATOM   2612 S SD  . MET A 1 443  ? 159.986 159.601 86.192  1.00 120.57 ? 565  MET A SD  1 
ATOM   2613 C CE  . MET A 1 443  ? 159.267 158.967 84.680  1.00 109.11 ? 565  MET A CE  1 
ATOM   2614 N N   . ILE A 1 444  ? 159.620 162.725 88.862  1.00 104.00 ? 566  ILE A N   1 
ATOM   2615 C CA  . ILE A 1 444  ? 160.464 163.364 89.865  1.00 102.67 ? 566  ILE A CA  1 
ATOM   2616 C C   . ILE A 1 444  ? 161.930 163.039 89.606  1.00 102.59 ? 566  ILE A C   1 
ATOM   2617 O O   . ILE A 1 444  ? 162.764 163.938 89.445  1.00 103.95 ? 566  ILE A O   1 
ATOM   2618 C CB  . ILE A 1 444  ? 160.029 162.945 91.283  1.00 99.79  ? 566  ILE A CB  1 
ATOM   2619 C CG1 . ILE A 1 444  ? 158.662 163.543 91.617  1.00 100.06 ? 566  ILE A CG1 1 
ATOM   2620 C CG2 . ILE A 1 444  ? 161.039 163.421 92.312  1.00 98.30  ? 566  ILE A CG2 1 
ATOM   2621 C CD1 . ILE A 1 444  ? 158.121 163.130 92.977  1.00 99.39  ? 566  ILE A CD1 1 
ATOM   2622 N N   . TYR A 1 445  ? 162.265 161.752 89.539  1.00 102.93 ? 567  TYR A N   1 
ATOM   2623 C CA  . TYR A 1 445  ? 163.649 161.346 89.362  1.00 105.08 ? 567  TYR A CA  1 
ATOM   2624 C C   . TYR A 1 445  ? 163.677 160.091 88.504  1.00 104.55 ? 567  TYR A C   1 
ATOM   2625 O O   . TYR A 1 445  ? 162.803 159.228 88.615  1.00 102.68 ? 567  TYR A O   1 
ATOM   2626 C CB  . TYR A 1 445  ? 164.329 161.087 90.714  1.00 101.99 ? 567  TYR A CB  1 
ATOM   2627 C CG  . TYR A 1 445  ? 165.796 160.708 90.633  1.00 105.57 ? 567  TYR A CG  1 
ATOM   2628 C CD1 . TYR A 1 445  ? 166.771 161.680 90.375  1.00 109.18 ? 567  TYR A CD1 1 
ATOM   2629 C CD2 . TYR A 1 445  ? 166.202 159.381 90.786  1.00 103.56 ? 567  TYR A CD2 1 
ATOM   2630 C CE1 . TYR A 1 445  ? 168.126 161.337 90.300  1.00 108.82 ? 567  TYR A CE1 1 
ATOM   2631 C CE2 . TYR A 1 445  ? 167.548 159.023 90.714  1.00 106.42 ? 567  TYR A CE2 1 
ATOM   2632 C CZ  . TYR A 1 445  ? 168.498 160.006 90.468  1.00 108.28 ? 567  TYR A CZ  1 
ATOM   2633 O OH  . TYR A 1 445  ? 169.825 159.656 90.391  1.00 108.41 ? 567  TYR A OH  1 
ATOM   2634 N N   . GLN A 1 446  ? 164.691 159.998 87.649  1.00 105.04 ? 568  GLN A N   1 
ATOM   2635 C CA  . GLN A 1 446  ? 164.946 158.801 86.862  1.00 103.54 ? 568  GLN A CA  1 
ATOM   2636 C C   . GLN A 1 446  ? 166.395 158.392 87.073  1.00 107.89 ? 568  GLN A C   1 
ATOM   2637 O O   . GLN A 1 446  ? 167.295 159.235 87.008  1.00 109.83 ? 568  GLN A O   1 
ATOM   2638 C CB  . GLN A 1 446  ? 164.657 159.039 85.378  1.00 103.28 ? 568  GLN A CB  1 
ATOM   2639 C CG  . GLN A 1 446  ? 164.670 157.781 84.532  1.00 103.96 ? 568  GLN A CG  1 
ATOM   2640 C CD  . GLN A 1 446  ? 163.622 157.812 83.441  1.00 107.91 ? 568  GLN A CD  1 
ATOM   2641 O OE1 . GLN A 1 446  ? 162.804 158.730 83.378  1.00 109.21 ? 568  GLN A OE1 1 
ATOM   2642 N NE2 . GLN A 1 446  ? 163.638 156.806 82.576  1.00 107.02 ? 568  GLN A NE2 1 
ATOM   2643 N N   . SER A 1 447  ? 166.618 157.107 87.330  1.00 110.48 ? 569  SER A N   1 
ATOM   2644 C CA  . SER A 1 447  ? 167.938 156.583 87.642  1.00 113.09 ? 569  SER A CA  1 
ATOM   2645 C C   . SER A 1 447  ? 168.443 155.709 86.503  1.00 115.01 ? 569  SER A C   1 
ATOM   2646 O O   . SER A 1 447  ? 167.651 155.123 85.758  1.00 112.96 ? 569  SER A O   1 
ATOM   2647 C CB  . SER A 1 447  ? 167.915 155.779 88.942  1.00 110.74 ? 569  SER A CB  1 
ATOM   2648 O OG  . SER A 1 447  ? 169.181 155.200 89.199  1.00 114.22 ? 569  SER A OG  1 
ATOM   2649 N N   . GLN A 1 448  ? 169.770 155.625 86.372  1.00 116.74 ? 570  GLN A N   1 
ATOM   2650 C CA  . GLN A 1 448  ? 170.355 154.785 85.331  1.00 119.59 ? 570  GLN A CA  1 
ATOM   2651 C C   . GLN A 1 448  ? 170.511 153.344 85.805  1.00 119.22 ? 570  GLN A C   1 
ATOM   2652 O O   . GLN A 1 448  ? 170.796 152.446 85.004  1.00 119.55 ? 570  GLN A O   1 
ATOM   2653 C CB  . GLN A 1 448  ? 171.703 155.357 84.880  1.00 120.95 ? 570  GLN A CB  1 
ATOM   2654 C CG  . GLN A 1 448  ? 172.774 155.427 85.961  1.00 121.43 ? 570  GLN A CG  1 
ATOM   2655 C CD  . GLN A 1 448  ? 172.829 156.773 86.661  1.00 121.89 ? 570  GLN A CD  1 
ATOM   2656 O OE1 . GLN A 1 448  ? 171.914 157.587 86.540  1.00 120.84 ? 570  GLN A OE1 1 
ATOM   2657 N NE2 . GLN A 1 448  ? 173.905 157.011 87.401  1.00 121.21 ? 570  GLN A NE2 1 
ATOM   2658 N N   . GLU A 1 449  ? 170.327 153.105 87.097  1.00 117.62 ? 571  GLU A N   1 
ATOM   2659 C CA  . GLU A 1 449  ? 170.348 151.768 87.671  1.00 114.14 ? 571  GLU A CA  1 
ATOM   2660 C C   . GLU A 1 449  ? 169.039 151.502 88.409  1.00 112.34 ? 571  GLU A C   1 
ATOM   2661 O O   . GLU A 1 449  ? 168.222 152.402 88.612  1.00 110.95 ? 571  GLU A O   1 
ATOM   2662 C CB  . GLU A 1 449  ? 171.548 151.604 88.610  1.00 111.03 ? 571  GLU A CB  1 
ATOM   2663 C CG  . GLU A 1 449  ? 171.380 152.235 89.986  1.00 110.96 ? 571  GLU A CG  1 
ATOM   2664 C CD  . GLU A 1 449  ? 171.922 153.652 90.094  1.00 115.35 ? 571  GLU A CD  1 
ATOM   2665 O OE1 . GLU A 1 449  ? 172.039 154.346 89.064  1.00 117.02 ? 571  GLU A OE1 1 
ATOM   2666 O OE2 . GLU A 1 449  ? 172.231 154.079 91.226  1.00 113.73 ? 571  GLU A OE2 1 
ATOM   2667 N N   . GLU A 1 450  ? 168.840 150.242 88.794  1.00 110.61 ? 572  GLU A N   1 
ATOM   2668 C CA  . GLU A 1 450  ? 167.583 149.828 89.404  1.00 107.57 ? 572  GLU A CA  1 
ATOM   2669 C C   . GLU A 1 450  ? 167.499 150.269 90.863  1.00 103.26 ? 572  GLU A C   1 
ATOM   2670 O O   . GLU A 1 450  ? 168.505 150.304 91.571  1.00 103.35 ? 572  GLU A O   1 
ATOM   2671 C CB  . GLU A 1 450  ? 167.432 148.312 89.312  1.00 110.12 ? 572  GLU A CB  1 
ATOM   2672 C CG  . GLU A 1 450  ? 166.990 147.818 87.948  1.00 113.23 ? 572  GLU A CG  1 
ATOM   2673 C CD  . GLU A 1 450  ? 166.419 146.416 87.991  1.00 119.16 ? 572  GLU A CD  1 
ATOM   2674 O OE1 . GLU A 1 450  ? 166.407 145.810 89.083  1.00 120.63 ? 572  GLU A OE1 1 
ATOM   2675 O OE2 . GLU A 1 450  ? 165.985 145.918 86.932  1.00 121.11 ? 572  GLU A OE2 1 
ATOM   2676 N N   . LEU A 1 451  ? 166.282 150.587 91.314  1.00 99.79  ? 573  LEU A N   1 
ATOM   2677 C CA  . LEU A 1 451  ? 166.016 150.981 92.698  1.00 94.99  ? 573  LEU A CA  1 
ATOM   2678 C C   . LEU A 1 451  ? 165.655 149.747 93.515  1.00 92.83  ? 573  LEU A C   1 
ATOM   2679 O O   . LEU A 1 451  ? 165.158 148.756 92.972  1.00 94.67  ? 573  LEU A O   1 
ATOM   2680 C CB  . LEU A 1 451  ? 164.890 152.009 92.785  1.00 92.47  ? 573  LEU A CB  1 
ATOM   2681 C CG  . LEU A 1 451  ? 165.132 153.517 92.757  1.00 91.75  ? 573  LEU A CG  1 
ATOM   2682 C CD1 . LEU A 1 451  ? 165.518 154.018 91.382  1.00 97.45  ? 573  LEU A CD1 1 
ATOM   2683 C CD2 . LEU A 1 451  ? 163.858 154.193 93.229  1.00 91.71  ? 573  LEU A CD2 1 
ATOM   2684 N N   . ALA A 1 452  ? 165.902 149.815 94.825  1.00 86.61  ? 574  ALA A N   1 
ATOM   2685 C CA  . ALA A 1 452  ? 165.520 148.722 95.711  1.00 82.74  ? 574  ALA A CA  1 
ATOM   2686 C C   . ALA A 1 452  ? 164.432 149.157 96.686  1.00 79.29  ? 574  ALA A C   1 
ATOM   2687 O O   . ALA A 1 452  ? 163.388 148.505 96.796  1.00 83.81  ? 574  ALA A O   1 
ATOM   2688 C CB  . ALA A 1 452  ? 166.742 148.203 96.464  1.00 83.38  ? 574  ALA A CB  1 
ATOM   2689 N N   . ASP A 1 453  ? 164.660 150.253 97.408  1.00 75.02  ? 575  ASP A N   1 
ATOM   2690 C CA  . ASP A 1 453  ? 163.679 150.765 98.356  1.00 71.90  ? 575  ASP A CA  1 
ATOM   2691 C C   . ASP A 1 453  ? 163.838 152.271 98.463  1.00 73.34  ? 575  ASP A C   1 
ATOM   2692 O O   . ASP A 1 453  ? 164.885 152.821 98.113  1.00 77.81  ? 575  ASP A O   1 
ATOM   2693 C CB  . ASP A 1 453  ? 163.825 150.116 99.736  1.00 71.24  ? 575  ASP A CB  1 
ATOM   2694 C CG  . ASP A 1 453  ? 162.498 149.977 100.459 1.00 75.22  ? 575  ASP A CG  1 
ATOM   2695 O OD1 . ASP A 1 453  ? 162.298 148.957 101.150 1.00 79.36  ? 575  ASP A OD1 1 
ATOM   2696 O OD2 . ASP A 1 453  ? 161.650 150.885 100.344 1.00 74.89  ? 575  ASP A OD2 1 
ATOM   2697 N N   . ILE A 1 454  ? 162.782 152.938 98.934  1.00 70.06  ? 576  ILE A N   1 
ATOM   2698 C CA  . ILE A 1 454  ? 162.832 154.365 99.210  1.00 65.44  ? 576  ILE A CA  1 
ATOM   2699 C C   . ILE A 1 454  ? 162.322 154.616 100.621 1.00 63.63  ? 576  ILE A C   1 
ATOM   2700 O O   . ILE A 1 454  ? 161.780 153.732 101.285 1.00 66.31  ? 576  ILE A O   1 
ATOM   2701 C CB  . ILE A 1 454  ? 162.000 155.214 98.230  1.00 65.66  ? 576  ILE A CB  1 
ATOM   2702 C CG1 . ILE A 1 454  ? 160.578 154.697 98.138  1.00 68.24  ? 576  ILE A CG1 1 
ATOM   2703 C CG2 . ILE A 1 454  ? 162.643 155.259 96.851  1.00 71.19  ? 576  ILE A CG2 1 
ATOM   2704 C CD1 . ILE A 1 454  ? 159.635 155.806 97.817  1.00 69.77  ? 576  ILE A CD1 1 
ATOM   2705 N N   . ALA A 1 455  ? 162.487 155.860 101.059 1.00 62.24  ? 577  ALA A N   1 
ATOM   2706 C CA  . ALA A 1 455  ? 161.832 156.396 102.238 1.00 62.29  ? 577  ALA A CA  1 
ATOM   2707 C C   . ALA A 1 455  ? 161.271 157.762 101.875 1.00 67.24  ? 577  ALA A C   1 
ATOM   2708 O O   . ALA A 1 455  ? 161.631 158.341 100.848 1.00 70.17  ? 577  ALA A O   1 
ATOM   2709 C CB  . ALA A 1 455  ? 162.788 156.506 103.425 1.00 63.42  ? 577  ALA A CB  1 
ATOM   2710 N N   . TRP A 1 456  ? 160.379 158.277 102.714 1.00 66.13  ? 578  TRP A N   1 
ATOM   2711 C CA  . TRP A 1 456  ? 159.708 159.525 102.388 1.00 66.74  ? 578  TRP A CA  1 
ATOM   2712 C C   . TRP A 1 456  ? 159.381 160.296 103.657 1.00 70.64  ? 578  TRP A C   1 
ATOM   2713 O O   . TRP A 1 456  ? 159.277 159.730 104.748 1.00 69.60  ? 578  TRP A O   1 
ATOM   2714 C CB  . TRP A 1 456  ? 158.447 159.268 101.551 1.00 67.42  ? 578  TRP A CB  1 
ATOM   2715 C CG  . TRP A 1 456  ? 157.242 158.896 102.351 1.00 71.90  ? 578  TRP A CG  1 
ATOM   2716 C CD1 . TRP A 1 456  ? 156.982 157.683 102.916 1.00 73.99  ? 578  TRP A CD1 1 
ATOM   2717 C CD2 . TRP A 1 456  ? 156.123 159.730 102.656 1.00 71.31  ? 578  TRP A CD2 1 
ATOM   2718 N NE1 . TRP A 1 456  ? 155.774 157.712 103.565 1.00 72.70  ? 578  TRP A NE1 1 
ATOM   2719 C CE2 . TRP A 1 456  ? 155.225 158.957 103.421 1.00 71.01  ? 578  TRP A CE2 1 
ATOM   2720 C CE3 . TRP A 1 456  ? 155.791 161.057 102.361 1.00 72.38  ? 578  TRP A CE3 1 
ATOM   2721 C CZ2 . TRP A 1 456  ? 154.019 159.469 103.898 1.00 72.64  ? 578  TRP A CZ2 1 
ATOM   2722 C CZ3 . TRP A 1 456  ? 154.595 161.567 102.841 1.00 78.35  ? 578  TRP A CZ3 1 
ATOM   2723 C CH2 . TRP A 1 456  ? 153.722 160.771 103.597 1.00 78.59  ? 578  TRP A CH2 1 
ATOM   2724 N N   . SER A 1 457  ? 159.228 161.610 103.492 1.00 75.05  ? 579  SER A N   1 
ATOM   2725 C CA  . SER A 1 457  ? 158.884 162.526 104.569 1.00 75.27  ? 579  SER A CA  1 
ATOM   2726 C C   . SER A 1 457  ? 157.699 163.374 104.142 1.00 79.79  ? 579  SER A C   1 
ATOM   2727 O O   . SER A 1 457  ? 157.577 163.752 102.975 1.00 81.33  ? 579  SER A O   1 
ATOM   2728 C CB  . SER A 1 457  ? 160.039 163.453 104.909 1.00 77.06  ? 579  SER A CB  1 
ATOM   2729 O OG  . SER A 1 457  ? 161.177 162.736 105.319 1.00 75.27  ? 579  SER A OG  1 
ATOM   2730 N N   . LYS A 1 458  ? 156.829 163.684 105.097 1.00 80.92  ? 580  LYS A N   1 
ATOM   2731 C CA  . LYS A 1 458  ? 155.687 164.540 104.813 1.00 83.99  ? 580  LYS A CA  1 
ATOM   2732 C C   . LYS A 1 458  ? 155.964 166.004 105.117 1.00 91.27  ? 580  LYS A C   1 
ATOM   2733 O O   . LYS A 1 458  ? 155.603 166.876 104.320 1.00 93.76  ? 580  LYS A O   1 
ATOM   2734 C CB  . LYS A 1 458  ? 154.461 164.064 105.603 1.00 81.85  ? 580  LYS A CB  1 
ATOM   2735 C CG  . LYS A 1 458  ? 153.152 164.782 105.276 1.00 84.28  ? 580  LYS A CG  1 
ATOM   2736 C CD  . LYS A 1 458  ? 152.850 164.787 103.783 1.00 84.73  ? 580  LYS A CD  1 
ATOM   2737 C CE  . LYS A 1 458  ? 151.654 165.669 103.468 1.00 87.58  ? 580  LYS A CE  1 
ATOM   2738 N NZ  . LYS A 1 458  ? 151.464 165.844 102.001 1.00 83.26  ? 580  LYS A NZ  1 
ATOM   2739 N N   . ARG A 1 459  ? 156.620 166.296 106.238 1.00 90.74  ? 581  ARG A N   1 
ATOM   2740 C CA  . ARG A 1 459  ? 156.838 167.681 106.632 1.00 91.61  ? 581  ARG A CA  1 
ATOM   2741 C C   . ARG A 1 459  ? 158.224 168.185 106.264 1.00 90.70  ? 581  ARG A C   1 
ATOM   2742 O O   . ARG A 1 459  ? 158.391 169.376 105.980 1.00 93.84  ? 581  ARG A O   1 
ATOM   2743 C CB  . ARG A 1 459  ? 156.588 167.834 108.131 1.00 91.82  ? 581  ARG A CB  1 
ATOM   2744 C CG  . ARG A 1 459  ? 155.133 167.615 108.466 1.00 94.03  ? 581  ARG A CG  1 
ATOM   2745 C CD  . ARG A 1 459  ? 154.945 166.912 109.783 1.00 97.35  ? 581  ARG A CD  1 
ATOM   2746 N NE  . ARG A 1 459  ? 153.681 166.189 109.799 1.00 99.48  ? 581  ARG A NE  1 
ATOM   2747 C CZ  . ARG A 1 459  ? 153.543 164.921 109.438 1.00 97.40  ? 581  ARG A CZ  1 
ATOM   2748 N NH1 . ARG A 1 459  ? 154.582 164.195 109.058 1.00 93.28  ? 581  ARG A NH1 1 
ATOM   2749 N NH2 . ARG A 1 459  ? 152.336 164.363 109.474 1.00 94.98  ? 581  ARG A NH2 1 
ATOM   2750 N N   . GLU A 1 460  ? 159.228 167.309 106.261 1.00 85.66  ? 582  GLU A N   1 
ATOM   2751 C CA  . GLU A 1 460  ? 160.533 167.694 105.742 1.00 86.77  ? 582  GLU A CA  1 
ATOM   2752 C C   . GLU A 1 460  ? 160.589 167.627 104.225 1.00 85.39  ? 582  GLU A C   1 
ATOM   2753 O O   . GLU A 1 460  ? 161.486 168.250 103.639 1.00 84.78  ? 582  GLU A O   1 
ATOM   2754 C CB  . GLU A 1 460  ? 161.631 166.814 106.342 1.00 84.87  ? 582  GLU A CB  1 
ATOM   2755 C CG  . GLU A 1 460  ? 161.726 166.902 107.855 1.00 89.68  ? 582  GLU A CG  1 
ATOM   2756 C CD  . GLU A 1 460  ? 160.996 165.773 108.554 1.00 93.69  ? 582  GLU A CD  1 
ATOM   2757 O OE1 . GLU A 1 460  ? 160.816 164.706 107.937 1.00 94.17  ? 582  GLU A OE1 1 
ATOM   2758 O OE2 . GLU A 1 460  ? 160.570 165.965 109.708 1.00 93.24  ? 582  GLU A OE2 1 
ATOM   2759 N N   . GLN A 1 461  ? 159.646 166.884 103.615 1.00 85.06  ? 583  GLN A N   1 
ATOM   2760 C CA  . GLN A 1 461  ? 159.486 166.651 102.165 1.00 85.63  ? 583  GLN A CA  1 
ATOM   2761 C C   . GLN A 1 461  ? 160.741 166.058 101.524 1.00 82.41  ? 583  GLN A C   1 
ATOM   2762 O O   . GLN A 1 461  ? 161.106 166.386 100.395 1.00 85.16  ? 583  GLN A O   1 
ATOM   2763 C CB  . GLN A 1 461  ? 159.036 167.916 101.432 1.00 88.31  ? 583  GLN A CB  1 
ATOM   2764 C CG  . GLN A 1 461  ? 157.629 168.356 101.784 1.00 90.12  ? 583  GLN A CG  1 
ATOM   2765 C CD  . GLN A 1 461  ? 157.242 169.654 101.110 1.00 97.26  ? 583  GLN A CD  1 
ATOM   2766 O OE1 . GLN A 1 461  ? 158.058 170.284 100.439 1.00 100.70 ? 583  GLN A OE1 1 
ATOM   2767 N NE2 . GLN A 1 461  ? 155.993 170.062 101.287 1.00 96.81  ? 583  GLN A NE2 1 
ATOM   2768 N N   . GLN A 1 462  ? 161.399 165.170 102.257 1.00 79.41  ? 584  GLN A N   1 
ATOM   2769 C CA  . GLN A 1 462  ? 162.633 164.540 101.823 1.00 79.10  ? 584  GLN A CA  1 
ATOM   2770 C C   . GLN A 1 462  ? 162.315 163.122 101.378 1.00 78.01  ? 584  GLN A C   1 
ATOM   2771 O O   . GLN A 1 462  ? 161.430 162.476 101.945 1.00 81.01  ? 584  GLN A O   1 
ATOM   2772 C CB  . GLN A 1 462  ? 163.675 164.539 102.942 1.00 78.38  ? 584  GLN A CB  1 
ATOM   2773 C CG  . GLN A 1 462  ? 165.106 164.480 102.451 1.00 78.60  ? 584  GLN A CG  1 
ATOM   2774 C CD  . GLN A 1 462  ? 166.082 165.031 103.463 1.00 84.08  ? 584  GLN A CD  1 
ATOM   2775 O OE1 . GLN A 1 462  ? 165.687 165.523 104.519 1.00 86.46  ? 584  GLN A OE1 1 
ATOM   2776 N NE2 . GLN A 1 462  ? 167.369 164.960 103.144 1.00 86.99  ? 584  GLN A NE2 1 
ATOM   2777 N N   . LEU A 1 463  ? 163.026 162.648 100.360 1.00 75.43  ? 585  LEU A N   1 
ATOM   2778 C CA  . LEU A 1 463  ? 162.710 161.377 99.724  1.00 70.82  ? 585  LEU A CA  1 
ATOM   2779 C C   . LEU A 1 463  ? 164.032 160.696 99.403  1.00 74.29  ? 585  LEU A C   1 
ATOM   2780 O O   . LEU A 1 463  ? 164.644 160.976 98.368  1.00 79.55  ? 585  LEU A O   1 
ATOM   2781 C CB  . LEU A 1 463  ? 161.854 161.613 98.475  1.00 75.38  ? 585  LEU A CB  1 
ATOM   2782 C CG  . LEU A 1 463  ? 161.161 160.550 97.616  1.00 79.81  ? 585  LEU A CG  1 
ATOM   2783 C CD1 . LEU A 1 463  ? 159.979 161.221 96.979  1.00 84.66  ? 585  LEU A CD1 1 
ATOM   2784 C CD2 . LEU A 1 463  ? 161.996 159.964 96.524  1.00 77.85  ? 585  LEU A CD2 1 
ATOM   2785 N N   . TRP A 1 464  ? 164.489 159.833 100.304 1.00 72.68  ? 586  TRP A N   1 
ATOM   2786 C CA  . TRP A 1 464  ? 165.734 159.101 100.136 1.00 72.35  ? 586  TRP A CA  1 
ATOM   2787 C C   . TRP A 1 464  ? 165.523 157.937 99.183  1.00 71.92  ? 586  TRP A C   1 
ATOM   2788 O O   . TRP A 1 464  ? 164.443 157.356 99.130  1.00 75.23  ? 586  TRP A O   1 
ATOM   2789 C CB  . TRP A 1 464  ? 166.251 158.580 101.474 1.00 71.90  ? 586  TRP A CB  1 
ATOM   2790 C CG  . TRP A 1 464  ? 166.507 159.658 102.449 1.00 72.96  ? 586  TRP A CG  1 
ATOM   2791 C CD1 . TRP A 1 464  ? 167.674 160.329 102.637 1.00 76.54  ? 586  TRP A CD1 1 
ATOM   2792 C CD2 . TRP A 1 464  ? 165.574 160.201 103.378 1.00 70.30  ? 586  TRP A CD2 1 
ATOM   2793 N NE1 . TRP A 1 464  ? 167.526 161.265 103.629 1.00 77.04  ? 586  TRP A NE1 1 
ATOM   2794 C CE2 . TRP A 1 464  ? 166.243 161.205 104.101 1.00 73.80  ? 586  TRP A CE2 1 
ATOM   2795 C CE3 . TRP A 1 464  ? 164.232 159.935 103.668 1.00 70.73  ? 586  TRP A CE3 1 
ATOM   2796 C CZ2 . TRP A 1 464  ? 165.615 161.947 105.098 1.00 73.40  ? 586  TRP A CZ2 1 
ATOM   2797 C CZ3 . TRP A 1 464  ? 163.610 160.667 104.658 1.00 71.69  ? 586  TRP A CZ3 1 
ATOM   2798 C CH2 . TRP A 1 464  ? 164.301 161.665 105.359 1.00 71.33  ? 586  TRP A CH2 1 
ATOM   2799 N N   . LEU A 1 465  ? 166.564 157.602 98.426  1.00 73.52  ? 587  LEU A N   1 
ATOM   2800 C CA  . LEU A 1 465  ? 166.504 156.475 97.501  1.00 73.68  ? 587  LEU A CA  1 
ATOM   2801 C C   . LEU A 1 465  ? 167.615 155.509 97.853  1.00 80.28  ? 587  LEU A C   1 
ATOM   2802 O O   . LEU A 1 465  ? 168.680 155.929 98.312  1.00 86.40  ? 587  LEU A O   1 
ATOM   2803 C CB  . LEU A 1 465  ? 166.669 156.889 96.042  1.00 76.83  ? 587  LEU A CB  1 
ATOM   2804 C CG  . LEU A 1 465  ? 165.609 157.577 95.198  1.00 80.31  ? 587  LEU A CG  1 
ATOM   2805 C CD1 . LEU A 1 465  ? 165.508 159.061 95.492  1.00 78.01  ? 587  LEU A CD1 1 
ATOM   2806 C CD2 . LEU A 1 465  ? 165.947 157.318 93.771  1.00 89.02  ? 587  LEU A CD2 1 
ATOM   2807 N N   . LEU A 1 466  ? 167.381 154.227 97.620  1.00 79.44  ? 588  LEU A N   1 
ATOM   2808 C CA  . LEU A 1 466  ? 168.412 153.212 97.772  1.00 79.80  ? 588  LEU A CA  1 
ATOM   2809 C C   . LEU A 1 466  ? 168.353 152.350 96.517  1.00 85.32  ? 588  LEU A C   1 
ATOM   2810 O O   . LEU A 1 466  ? 167.281 151.859 96.149  1.00 88.87  ? 588  LEU A O   1 
ATOM   2811 C CB  . LEU A 1 466  ? 168.174 152.410 99.049  1.00 75.51  ? 588  LEU A CB  1 
ATOM   2812 C CG  . LEU A 1 466  ? 169.251 151.546 99.697  1.00 78.60  ? 588  LEU A CG  1 
ATOM   2813 C CD1 . LEU A 1 466  ? 168.929 151.499 101.160 1.00 78.76  ? 588  LEU A CD1 1 
ATOM   2814 C CD2 . LEU A 1 466  ? 169.315 150.148 99.165  1.00 82.33  ? 588  LEU A CD2 1 
ATOM   2815 N N   . ASN A 1 467  ? 169.494 152.163 95.866  1.00 89.20  ? 589  ASN A N   1 
ATOM   2816 C CA  . ASN A 1 467  ? 169.497 151.451 94.600  1.00 91.20  ? 589  ASN A CA  1 
ATOM   2817 C C   . ASN A 1 467  ? 169.819 149.969 94.799  1.00 95.39  ? 589  ASN A C   1 
ATOM   2818 O O   . ASN A 1 467  ? 169.860 149.455 95.916  1.00 96.46  ? 589  ASN A O   1 
ATOM   2819 C CB  . ASN A 1 467  ? 170.470 152.105 93.617  1.00 92.84  ? 589  ASN A CB  1 
ATOM   2820 C CG  . ASN A 1 467  ? 171.845 152.368 94.210  1.00 98.38  ? 589  ASN A CG  1 
ATOM   2821 O OD1 . ASN A 1 467  ? 172.133 152.016 95.348  1.00 100.19 ? 589  ASN A OD1 1 
ATOM   2822 N ND2 . ASN A 1 467  ? 172.709 152.991 93.417  1.00 102.64 ? 589  ASN A ND2 1 
ATOM   2823 N N   . VAL A 1 468  ? 170.066 149.278 93.684  1.00 97.89  ? 590  VAL A N   1 
ATOM   2824 C CA  . VAL A 1 468  ? 170.449 147.874 93.761  1.00 99.46  ? 590  VAL A CA  1 
ATOM   2825 C C   . VAL A 1 468  ? 171.933 147.739 94.120  1.00 101.71 ? 590  VAL A C   1 
ATOM   2826 O O   . VAL A 1 468  ? 172.349 146.717 94.680  1.00 102.11 ? 590  VAL A O   1 
ATOM   2827 C CB  . VAL A 1 468  ? 170.043 147.176 92.428  1.00 99.26  ? 590  VAL A CB  1 
ATOM   2828 C CG1 . VAL A 1 468  ? 170.840 147.693 91.234  1.00 101.53 ? 590  VAL A CG1 1 
ATOM   2829 C CG2 . VAL A 1 468  ? 170.045 145.640 92.522  1.00 97.53  ? 590  VAL A CG2 1 
ATOM   2830 N N   . HIS A 1 469  ? 172.732 148.785 93.894  1.00 103.08 ? 591  HIS A N   1 
ATOM   2831 C CA  . HIS A 1 469  ? 174.157 148.775 94.211  1.00 103.11 ? 591  HIS A CA  1 
ATOM   2832 C C   . HIS A 1 469  ? 174.458 149.322 95.604  1.00 102.92 ? 591  HIS A C   1 
ATOM   2833 O O   . HIS A 1 469  ? 175.628 149.361 96.001  1.00 104.76 ? 591  HIS A O   1 
ATOM   2834 C CB  . HIS A 1 469  ? 174.956 149.564 93.164  1.00 102.65 ? 591  HIS A CB  1 
ATOM   2835 C CG  . HIS A 1 469  ? 174.834 149.052 91.757  1.00 106.85 ? 591  HIS A CG  1 
ATOM   2836 N ND1 . HIS A 1 469  ? 174.307 147.818 91.439  1.00 107.49 ? 591  HIS A ND1 1 
ATOM   2837 C CD2 . HIS A 1 469  ? 175.173 149.626 90.578  1.00 108.86 ? 591  HIS A CD2 1 
ATOM   2838 C CE1 . HIS A 1 469  ? 174.328 147.653 90.129  1.00 108.76 ? 591  HIS A CE1 1 
ATOM   2839 N NE2 . HIS A 1 469  ? 174.849 148.736 89.582  1.00 110.52 ? 591  HIS A NE2 1 
ATOM   2840 N N   . GLY A 1 470  ? 173.439 149.739 96.348  1.00 100.30 ? 592  GLY A N   1 
ATOM   2841 C CA  . GLY A 1 470  ? 173.647 150.163 97.726  1.00 97.84  ? 592  GLY A CA  1 
ATOM   2842 C C   . GLY A 1 470  ? 174.223 151.550 97.907  1.00 100.29 ? 592  GLY A C   1 
ATOM   2843 O O   . GLY A 1 470  ? 174.948 151.792 98.879  1.00 102.62 ? 592  GLY A O   1 
ATOM   2844 N N   . GLU A 1 471  ? 173.914 152.474 97.001  1.00 98.94  ? 593  GLU A N   1 
ATOM   2845 C CA  . GLU A 1 471  ? 174.273 153.879 97.154  1.00 96.92  ? 593  GLU A CA  1 
ATOM   2846 C C   . GLU A 1 471  ? 173.025 154.656 97.542  1.00 93.49  ? 593  GLU A C   1 
ATOM   2847 O O   . GLU A 1 471  ? 172.003 154.579 96.854  1.00 94.51  ? 593  GLU A O   1 
ATOM   2848 C CB  . GLU A 1 471  ? 174.868 154.451 95.866  1.00 99.40  ? 593  GLU A CB  1 
ATOM   2849 C CG  . GLU A 1 471  ? 176.087 153.711 95.353  1.00 104.79 ? 593  GLU A CG  1 
ATOM   2850 C CD  . GLU A 1 471  ? 176.540 154.211 93.996  1.00 113.40 ? 593  GLU A CD  1 
ATOM   2851 O OE1 . GLU A 1 471  ? 176.041 155.265 93.552  1.00 114.44 ? 593  GLU A OE1 1 
ATOM   2852 O OE2 . GLU A 1 471  ? 177.397 153.550 93.374  1.00 116.69 ? 593  GLU A OE2 1 
ATOM   2853 N N   . LEU A 1 472  ? 173.113 155.406 98.631  1.00 91.11  ? 594  LEU A N   1 
ATOM   2854 C CA  . LEU A 1 472  ? 171.973 156.118 99.186  1.00 86.68  ? 594  LEU A CA  1 
ATOM   2855 C C   . LEU A 1 472  ? 171.979 157.557 98.686  1.00 90.89  ? 594  LEU A C   1 
ATOM   2856 O O   . LEU A 1 472  ? 172.937 158.297 98.932  1.00 97.97  ? 594  LEU A O   1 
ATOM   2857 C CB  . LEU A 1 472  ? 172.023 156.086 100.712 1.00 83.73  ? 594  LEU A CB  1 
ATOM   2858 C CG  . LEU A 1 472  ? 171.049 156.970 101.480 1.00 84.94  ? 594  LEU A CG  1 
ATOM   2859 C CD1 . LEU A 1 472  ? 169.674 156.336 101.541 1.00 79.56  ? 594  LEU A CD1 1 
ATOM   2860 C CD2 . LEU A 1 472  ? 171.590 157.248 102.868 1.00 88.13  ? 594  LEU A CD2 1 
ATOM   2861 N N   . ARG A 1 473  ? 170.914 157.947 97.988  1.00 86.08  ? 595  ARG A N   1 
ATOM   2862 C CA  . ARG A 1 473  ? 170.777 159.295 97.453  1.00 85.40  ? 595  ARG A CA  1 
ATOM   2863 C C   . ARG A 1 473  ? 169.567 159.967 98.078  1.00 82.56  ? 595  ARG A C   1 
ATOM   2864 O O   . ARG A 1 473  ? 168.493 159.370 98.163  1.00 84.60  ? 595  ARG A O   1 
ATOM   2865 C CB  . ARG A 1 473  ? 170.634 159.288 95.926  1.00 86.79  ? 595  ARG A CB  1 
ATOM   2866 C CG  . ARG A 1 473  ? 171.665 158.442 95.206  1.00 93.57  ? 595  ARG A CG  1 
ATOM   2867 C CD  . ARG A 1 473  ? 171.875 158.914 93.779  1.00 102.14 ? 595  ARG A CD  1 
ATOM   2868 N NE  . ARG A 1 473  ? 172.882 158.114 93.092  1.00 109.79 ? 595  ARG A NE  1 
ATOM   2869 C CZ  . ARG A 1 473  ? 173.289 158.326 91.848  1.00 114.47 ? 595  ARG A CZ  1 
ATOM   2870 N NH1 . ARG A 1 473  ? 172.799 159.315 91.120  1.00 117.91 ? 595  ARG A NH1 1 
ATOM   2871 N NH2 . ARG A 1 473  ? 174.214 157.529 91.324  1.00 113.71 ? 595  ARG A NH2 1 
ATOM   2872 N N   . SER A 1 474  ? 169.745 161.212 98.509  1.00 83.57  ? 596  SER A N   1 
ATOM   2873 C CA  . SER A 1 474  ? 168.690 161.996 99.136  1.00 83.85  ? 596  SER A CA  1 
ATOM   2874 C C   . SER A 1 474  ? 168.175 163.032 98.150  1.00 86.24  ? 596  SER A C   1 
ATOM   2875 O O   . SER A 1 474  ? 168.923 163.493 97.284  1.00 92.37  ? 596  SER A O   1 
ATOM   2876 C CB  . SER A 1 474  ? 169.198 162.689 100.400 1.00 87.02  ? 596  SER A CB  1 
ATOM   2877 O OG  . SER A 1 474  ? 168.332 163.744 100.778 1.00 87.62  ? 596  SER A OG  1 
ATOM   2878 N N   . LEU A 1 475  ? 166.907 163.404 98.293  1.00 80.41  ? 597  LEU A N   1 
ATOM   2879 C CA  . LEU A 1 475  ? 166.242 164.312 97.373  1.00 82.88  ? 597  LEU A CA  1 
ATOM   2880 C C   . LEU A 1 475  ? 165.102 165.007 98.104  1.00 86.34  ? 597  LEU A C   1 
ATOM   2881 O O   . LEU A 1 475  ? 164.504 164.439 99.017  1.00 86.50  ? 597  LEU A O   1 
ATOM   2882 C CB  . LEU A 1 475  ? 165.750 163.532 96.126  1.00 79.96  ? 597  LEU A CB  1 
ATOM   2883 C CG  . LEU A 1 475  ? 164.837 164.038 95.006  1.00 86.68  ? 597  LEU A CG  1 
ATOM   2884 C CD1 . LEU A 1 475  ? 165.259 163.396 93.708  1.00 92.67  ? 597  LEU A CD1 1 
ATOM   2885 C CD2 . LEU A 1 475  ? 163.386 163.672 95.274  1.00 89.72  ? 597  LEU A CD2 1 
ATOM   2886 N N   . LYS A 1 476  ? 164.799 166.235 97.692  1.00 88.60  ? 598  LYS A N   1 
ATOM   2887 C CA  . LYS A 1 476  ? 163.672 166.995 98.218  1.00 85.65  ? 598  LYS A CA  1 
ATOM   2888 C C   . LYS A 1 476  ? 162.768 167.398 97.064  1.00 90.66  ? 598  LYS A C   1 
ATOM   2889 O O   . LYS A 1 476  ? 163.234 167.547 95.931  1.00 94.40  ? 598  LYS A O   1 
ATOM   2890 C CB  . LYS A 1 476  ? 164.143 168.230 98.987  1.00 86.98  ? 598  LYS A CB  1 
ATOM   2891 C CG  . LYS A 1 476  ? 164.859 167.909 100.289 1.00 86.15  ? 598  LYS A CG  1 
ATOM   2892 C CD  . LYS A 1 476  ? 165.365 169.167 100.970 1.00 86.80  ? 598  LYS A CD  1 
ATOM   2893 C CE  . LYS A 1 476  ? 164.216 169.990 101.524 1.00 87.37  ? 598  LYS A CE  1 
ATOM   2894 N NZ  . LYS A 1 476  ? 163.539 169.301 102.656 1.00 85.18  ? 598  LYS A NZ  1 
ATOM   2895 N N   . PHE A 1 477  ? 161.478 167.561 97.347  1.00 93.67  ? 599  PHE A N   1 
ATOM   2896 C CA  . PHE A 1 477  ? 160.473 167.763 96.311  1.00 96.64  ? 599  PHE A CA  1 
ATOM   2897 C C   . PHE A 1 477  ? 159.282 168.515 96.888  1.00 99.14  ? 599  PHE A C   1 
ATOM   2898 O O   . PHE A 1 477  ? 159.032 168.462 98.096  1.00 97.94  ? 599  PHE A O   1 
ATOM   2899 C CB  . PHE A 1 477  ? 160.004 166.409 95.720  1.00 95.02  ? 599  PHE A CB  1 
ATOM   2900 C CG  . PHE A 1 477  ? 159.035 165.634 96.600  1.00 93.57  ? 599  PHE A CG  1 
ATOM   2901 C CD1 . PHE A 1 477  ? 159.476 164.959 97.745  1.00 88.49  ? 599  PHE A CD1 1 
ATOM   2902 C CD2 . PHE A 1 477  ? 157.689 165.516 96.227  1.00 97.31  ? 599  PHE A CD2 1 
ATOM   2903 C CE1 . PHE A 1 477  ? 158.582 164.247 98.544  1.00 86.97  ? 599  PHE A CE1 1 
ATOM   2904 C CE2 . PHE A 1 477  ? 156.789 164.801 97.013  1.00 95.51  ? 599  PHE A CE2 1 
ATOM   2905 C CZ  . PHE A 1 477  ? 157.242 164.162 98.169  1.00 89.84  ? 599  PHE A CZ  1 
ATOM   2906 N N   . GLU A 1 478  ? 158.545 169.204 96.016  1.00 104.32 ? 600  GLU A N   1 
ATOM   2907 C CA  . GLU A 1 478  ? 157.189 169.665 96.304  1.00 106.05 ? 600  GLU A CA  1 
ATOM   2908 C C   . GLU A 1 478  ? 156.407 169.673 94.995  1.00 108.06 ? 600  GLU A C   1 
ATOM   2909 O O   . GLU A 1 478  ? 156.950 170.075 93.957  1.00 110.23 ? 600  GLU A O   1 
ATOM   2910 C CB  . GLU A 1 478  ? 157.185 171.036 97.017  1.00 107.48 ? 600  GLU A CB  1 
ATOM   2911 C CG  . GLU A 1 478  ? 157.792 172.273 96.315  1.00 112.40 ? 600  GLU A CG  1 
ATOM   2912 C CD  . GLU A 1 478  ? 156.821 173.005 95.397  1.00 118.19 ? 600  GLU A CD  1 
ATOM   2913 O OE1 . GLU A 1 478  ? 155.596 172.821 95.557  1.00 118.20 ? 600  GLU A OE1 1 
ATOM   2914 O OE2 . GLU A 1 478  ? 157.286 173.764 94.521  1.00 119.35 ? 600  GLU A OE2 1 
ATOM   2915 N N   . SER A 1 479  ? 155.170 169.150 95.057  1.00 107.96 ? 601  SER A N   1 
ATOM   2916 C CA  . SER A 1 479  ? 154.135 169.185 94.004  1.00 112.46 ? 601  SER A CA  1 
ATOM   2917 C C   . SER A 1 479  ? 154.563 168.478 92.714  1.00 112.49 ? 601  SER A C   1 
ATOM   2918 O O   . SER A 1 479  ? 154.183 168.864 91.606  1.00 112.90 ? 601  SER A O   1 
ATOM   2919 C CB  . SER A 1 479  ? 153.680 170.620 93.715  1.00 112.89 ? 601  SER A CB  1 
ATOM   2920 O OG  . SER A 1 479  ? 152.460 170.633 92.995  1.00 110.06 ? 601  SER A OG  1 
ATOM   2921 N N   . GLY A 1 480  ? 155.368 167.431 92.864  1.00 110.24 ? 602  GLY A N   1 
ATOM   2922 C CA  . GLY A 1 480  ? 155.850 166.678 91.729  1.00 110.42 ? 602  GLY A CA  1 
ATOM   2923 C C   . GLY A 1 480  ? 157.023 167.277 90.994  1.00 112.43 ? 602  GLY A C   1 
ATOM   2924 O O   . GLY A 1 480  ? 157.316 166.838 89.876  1.00 112.51 ? 602  GLY A O   1 
ATOM   2925 N N   . GLN A 1 481  ? 157.697 168.264 91.572  1.00 109.92 ? 603  GLN A N   1 
ATOM   2926 C CA  . GLN A 1 481  ? 158.851 168.881 90.942  1.00 110.90 ? 603  GLN A CA  1 
ATOM   2927 C C   . GLN A 1 481  ? 160.048 168.788 91.873  1.00 110.06 ? 603  GLN A C   1 
ATOM   2928 O O   . GLN A 1 481  ? 159.910 168.816 93.098  1.00 108.42 ? 603  GLN A O   1 
ATOM   2929 C CB  . GLN A 1 481  ? 158.578 170.342 90.571  1.00 113.90 ? 603  GLN A CB  1 
ATOM   2930 C CG  . GLN A 1 481  ? 157.725 170.499 89.325  1.00 116.85 ? 603  GLN A CG  1 
ATOM   2931 C CD  . GLN A 1 481  ? 158.386 169.909 88.096  1.00 119.52 ? 603  GLN A CD  1 
ATOM   2932 O OE1 . GLN A 1 481  ? 157.903 168.930 87.526  1.00 119.07 ? 603  GLN A OE1 1 
ATOM   2933 N NE2 . GLN A 1 481  ? 159.501 170.499 87.683  1.00 118.93 ? 603  GLN A NE2 1 
ATOM   2934 N N   . MET A 1 482  ? 161.226 168.682 91.270  1.00 111.88 ? 604  MET A N   1 
ATOM   2935 C CA  . MET A 1 482  ? 162.474 168.476 92.000  1.00 111.05 ? 604  MET A CA  1 
ATOM   2936 C C   . MET A 1 482  ? 163.108 169.836 92.264  1.00 113.56 ? 604  MET A C   1 
ATOM   2937 O O   . MET A 1 482  ? 163.477 170.555 91.333  1.00 115.65 ? 604  MET A O   1 
ATOM   2938 C CB  . MET A 1 482  ? 163.394 167.568 91.193  1.00 110.47 ? 604  MET A CB  1 
ATOM   2939 C CG  . MET A 1 482  ? 164.698 167.232 91.860  1.00 109.82 ? 604  MET A CG  1 
ATOM   2940 S SD  . MET A 1 482  ? 165.710 166.137 90.851  1.00 119.49 ? 604  MET A SD  1 
ATOM   2941 C CE  . MET A 1 482  ? 166.219 167.259 89.552  1.00 111.67 ? 604  MET A CE  1 
ATOM   2942 N N   . VAL A 1 483  ? 163.239 170.199 93.544  1.00 110.73 ? 605  VAL A N   1 
ATOM   2943 C CA  . VAL A 1 483  ? 163.758 171.523 93.880  1.00 111.07 ? 605  VAL A CA  1 
ATOM   2944 C C   . VAL A 1 483  ? 165.202 171.434 94.357  1.00 107.65 ? 605  VAL A C   1 
ATOM   2945 O O   . VAL A 1 483  ? 165.943 172.424 94.326  1.00 107.74 ? 605  VAL A O   1 
ATOM   2946 C CB  . VAL A 1 483  ? 162.849 172.209 94.920  1.00 109.52 ? 605  VAL A CB  1 
ATOM   2947 C CG1 . VAL A 1 483  ? 161.521 172.586 94.288  1.00 108.01 ? 605  VAL A CG1 1 
ATOM   2948 C CG2 . VAL A 1 483  ? 162.619 171.307 96.123  1.00 103.66 ? 605  VAL A CG2 1 
ATOM   2949 N N   . SER A 1 484  ? 165.630 170.254 94.798  1.00 105.00 ? 606  SER A N   1 
ATOM   2950 C CA  . SER A 1 484  ? 167.013 170.036 95.182  1.00 105.72 ? 606  SER A CA  1 
ATOM   2951 C C   . SER A 1 484  ? 167.562 168.844 94.419  1.00 106.58 ? 606  SER A C   1 
ATOM   2952 O O   . SER A 1 484  ? 166.867 167.823 94.333  1.00 105.24 ? 606  SER A O   1 
ATOM   2953 C CB  . SER A 1 484  ? 167.134 169.791 96.690  1.00 101.10 ? 606  SER A CB  1 
ATOM   2954 O OG  . SER A 1 484  ? 166.881 168.435 97.005  1.00 98.26  ? 606  SER A OG  1 
ATOM   2955 N N   . PRO A 1 485  ? 168.767 168.932 93.841  1.00 106.90 ? 607  PRO A N   1 
ATOM   2956 C CA  . PRO A 1 485  ? 169.322 167.792 93.097  1.00 105.55 ? 607  PRO A CA  1 
ATOM   2957 C C   . PRO A 1 485  ? 169.764 166.664 94.019  1.00 102.70 ? 607  PRO A C   1 
ATOM   2958 O O   . PRO A 1 485  ? 169.950 166.845 95.223  1.00 102.13 ? 607  PRO A O   1 
ATOM   2959 C CB  . PRO A 1 485  ? 170.520 168.400 92.354  1.00 104.03 ? 607  PRO A CB  1 
ATOM   2960 C CG  . PRO A 1 485  ? 170.274 169.874 92.357  1.00 104.67 ? 607  PRO A CG  1 
ATOM   2961 C CD  . PRO A 1 485  ? 169.585 170.143 93.654  1.00 104.74 ? 607  PRO A CD  1 
ATOM   2962 N N   . ALA A 1 486  ? 169.905 165.480 93.430  1.00 100.39 ? 608  ALA A N   1 
ATOM   2963 C CA  . ALA A 1 486  ? 170.128 164.276 94.217  1.00 97.71  ? 608  ALA A CA  1 
ATOM   2964 C C   . ALA A 1 486  ? 171.581 164.167 94.657  1.00 100.64 ? 608  ALA A C   1 
ATOM   2965 O O   . ALA A 1 486  ? 172.456 163.775 93.882  1.00 102.59 ? 608  ALA A O   1 
ATOM   2966 C CB  . ALA A 1 486  ? 169.732 163.041 93.410  1.00 98.06  ? 608  ALA A CB  1 
ATOM   2967 N N   . GLN A 1 487  ? 171.836 164.507 95.920  1.00 97.68  ? 609  GLN A N   1 
ATOM   2968 C CA  . GLN A 1 487  ? 173.173 164.396 96.485  1.00 98.31  ? 609  GLN A CA  1 
ATOM   2969 C C   . GLN A 1 487  ? 173.363 162.970 96.980  1.00 98.45  ? 609  GLN A C   1 
ATOM   2970 O O   . GLN A 1 487  ? 172.397 162.305 97.365  1.00 96.50  ? 609  GLN A O   1 
ATOM   2971 C CB  . GLN A 1 487  ? 173.420 165.426 97.610  1.00 97.43  ? 609  GLN A CB  1 
ATOM   2972 C CG  . GLN A 1 487  ? 172.702 165.217 98.954  1.00 97.78  ? 609  GLN A CG  1 
ATOM   2973 C CD  . GLN A 1 487  ? 171.317 165.838 99.022  1.00 99.45  ? 609  GLN A CD  1 
ATOM   2974 O OE1 . GLN A 1 487  ? 170.722 166.182 98.005  1.00 98.56  ? 609  GLN A OE1 1 
ATOM   2975 N NE2 . GLN A 1 487  ? 170.801 165.988 100.237 1.00 97.17  ? 609  GLN A NE2 1 
ATOM   2976 N N   . GLN A 1 488  ? 174.597 162.482 96.906  1.00 101.40 ? 610  GLN A N   1 
ATOM   2977 C CA  . GLN A 1 488  ? 174.905 161.156 97.418  1.00 99.71  ? 610  GLN A CA  1 
ATOM   2978 C C   . GLN A 1 488  ? 175.313 161.253 98.877  1.00 100.40 ? 610  GLN A C   1 
ATOM   2979 O O   . GLN A 1 488  ? 176.326 161.875 99.211  1.00 105.20 ? 610  GLN A O   1 
ATOM   2980 C CB  . GLN A 1 488  ? 176.022 160.515 96.601  1.00 102.79 ? 610  GLN A CB  1 
ATOM   2981 C CG  . GLN A 1 488  ? 175.643 160.191 95.171  1.00 105.69 ? 610  GLN A CG  1 
ATOM   2982 C CD  . GLN A 1 488  ? 176.790 159.572 94.401  1.00 112.13 ? 610  GLN A CD  1 
ATOM   2983 O OE1 . GLN A 1 488  ? 177.899 159.442 94.916  1.00 112.19 ? 610  GLN A OE1 1 
ATOM   2984 N NE2 . GLN A 1 488  ? 176.527 159.189 93.158  1.00 113.33 ? 610  GLN A NE2 1 
ATOM   2985 N N   . LEU A 1 489  ? 174.526 160.636 99.749  1.00 96.40  ? 611  LEU A N   1 
ATOM   2986 C CA  . LEU A 1 489  ? 174.779 160.657 101.181 1.00 98.12  ? 611  LEU A CA  1 
ATOM   2987 C C   . LEU A 1 489  ? 175.307 159.285 101.580 1.00 99.56  ? 611  LEU A C   1 
ATOM   2988 O O   . LEU A 1 489  ? 174.600 158.278 101.457 1.00 97.67  ? 611  LEU A O   1 
ATOM   2989 C CB  . LEU A 1 489  ? 173.511 161.044 101.946 1.00 97.40  ? 611  LEU A CB  1 
ATOM   2990 C CG  . LEU A 1 489  ? 173.275 160.674 103.407 1.00 97.52  ? 611  LEU A CG  1 
ATOM   2991 C CD1 . LEU A 1 489  ? 174.190 161.490 104.295 1.00 96.53  ? 611  LEU A CD1 1 
ATOM   2992 C CD2 . LEU A 1 489  ? 171.823 160.933 103.750 1.00 90.83  ? 611  LEU A CD2 1 
ATOM   2993 N N   . LYS A 1 490  ? 176.573 159.240 101.980 1.00 105.53 ? 612  LYS A N   1 
ATOM   2994 C CA  . LYS A 1 490  ? 177.246 158.006 102.350 1.00 108.87 ? 612  LYS A CA  1 
ATOM   2995 C C   . LYS A 1 490  ? 177.048 157.725 103.833 1.00 108.71 ? 612  LYS A C   1 
ATOM   2996 O O   . LYS A 1 490  ? 176.827 158.637 104.633 1.00 110.51 ? 612  LYS A O   1 
ATOM   2997 C CB  . LYS A 1 490  ? 178.739 158.084 102.021 1.00 108.91 ? 612  LYS A CB  1 
ATOM   2998 C CG  . LYS A 1 490  ? 179.020 158.413 100.566 1.00 109.30 ? 612  LYS A CG  1 
ATOM   2999 C CD  . LYS A 1 490  ? 180.502 158.617 100.317 1.00 111.14 ? 612  LYS A CD  1 
ATOM   3000 C CE  . LYS A 1 490  ? 180.769 159.007 98.872  1.00 113.65 ? 612  LYS A CE  1 
ATOM   3001 N NZ  . LYS A 1 490  ? 182.215 159.249 98.621  1.00 113.00 ? 612  LYS A NZ  1 
ATOM   3002 N N   . LEU A 1 491  ? 177.122 156.448 104.194 1.00 106.37 ? 613  LEU A N   1 
ATOM   3003 C CA  . LEU A 1 491  ? 176.887 156.007 105.564 1.00 108.60 ? 613  LEU A CA  1 
ATOM   3004 C C   . LEU A 1 491  ? 178.226 155.874 106.281 1.00 115.39 ? 613  LEU A C   1 
ATOM   3005 O O   . LEU A 1 491  ? 179.072 155.063 105.890 1.00 116.81 ? 613  LEU A O   1 
ATOM   3006 C CB  . LEU A 1 491  ? 176.121 154.687 105.584 1.00 107.04 ? 613  LEU A CB  1 
ATOM   3007 C CG  . LEU A 1 491  ? 174.681 154.716 105.074 1.00 98.32  ? 613  LEU A CG  1 
ATOM   3008 C CD1 . LEU A 1 491  ? 174.056 153.341 105.195 1.00 89.42  ? 613  LEU A CD1 1 
ATOM   3009 C CD2 . LEU A 1 491  ? 173.859 155.747 105.832 1.00 96.41  ? 613  LEU A CD2 1 
ATOM   3010 N N   . ASP A 1 492  ? 178.415 156.676 107.330 1.00 118.23 ? 614  ASP A N   1 
ATOM   3011 C CA  . ASP A 1 492  ? 179.584 156.566 108.202 1.00 124.70 ? 614  ASP A CA  1 
ATOM   3012 C C   . ASP A 1 492  ? 179.226 155.619 109.343 1.00 124.88 ? 614  ASP A C   1 
ATOM   3013 O O   . ASP A 1 492  ? 178.703 156.013 110.389 1.00 125.30 ? 614  ASP A O   1 
ATOM   3014 C CB  . ASP A 1 492  ? 180.012 157.935 108.713 1.00 128.34 ? 614  ASP A CB  1 
ATOM   3015 C CG  . ASP A 1 492  ? 181.357 157.905 109.416 1.00 133.64 ? 614  ASP A CG  1 
ATOM   3016 O OD1 . ASP A 1 492  ? 182.144 156.967 109.164 1.00 131.24 ? 614  ASP A OD1 1 
ATOM   3017 O OD2 . ASP A 1 492  ? 181.625 158.819 110.224 1.00 135.37 ? 614  ASP A OD2 1 
ATOM   3018 N N   . LEU A 1 493  ? 179.509 154.335 109.121 1.00 122.10 ? 615  LEU A N   1 
ATOM   3019 C CA  . LEU A 1 493  ? 179.154 153.315 110.101 1.00 124.09 ? 615  LEU A CA  1 
ATOM   3020 C C   . LEU A 1 493  ? 180.132 153.303 111.273 1.00 131.68 ? 615  LEU A C   1 
ATOM   3021 O O   . LEU A 1 493  ? 179.712 153.259 112.435 1.00 132.41 ? 615  LEU A O   1 
ATOM   3022 C CB  . LEU A 1 493  ? 179.092 151.951 109.415 1.00 122.25 ? 615  LEU A CB  1 
ATOM   3023 C CG  . LEU A 1 493  ? 178.160 151.889 108.201 1.00 114.53 ? 615  LEU A CG  1 
ATOM   3024 C CD1 . LEU A 1 493  ? 178.226 150.540 107.510 1.00 113.89 ? 615  LEU A CD1 1 
ATOM   3025 C CD2 . LEU A 1 493  ? 176.731 152.195 108.614 1.00 112.00 ? 615  LEU A CD2 1 
ATOM   3026 N N   . GLY A 1 494  ? 181.430 153.351 110.991 1.00 134.23 ? 616  GLY A N   1 
ATOM   3027 C CA  . GLY A 1 494  ? 182.403 153.496 112.063 1.00 133.69 ? 616  GLY A CA  1 
ATOM   3028 C C   . GLY A 1 494  ? 182.746 152.174 112.721 1.00 134.41 ? 616  GLY A C   1 
ATOM   3029 O O   . GLY A 1 494  ? 183.131 151.202 112.061 1.00 132.50 ? 616  GLY A O   1 
ATOM   3030 N N   . ASN A 1 495  ? 182.597 152.133 114.050 1.00 135.87 ? 617  ASN A N   1 
ATOM   3031 C CA  . ASN A 1 495  ? 183.000 150.955 114.816 1.00 137.74 ? 617  ASN A CA  1 
ATOM   3032 C C   . ASN A 1 495  ? 181.894 149.907 114.860 1.00 135.13 ? 617  ASN A C   1 
ATOM   3033 O O   . ASN A 1 495  ? 182.102 148.799 115.369 1.00 133.02 ? 617  ASN A O   1 
ATOM   3034 C CB  . ASN A 1 495  ? 183.394 151.366 116.235 1.00 139.03 ? 617  ASN A CB  1 
ATOM   3035 C CG  . ASN A 1 495  ? 184.524 152.374 116.260 1.00 139.85 ? 617  ASN A CG  1 
ATOM   3036 O OD1 . ASN A 1 495  ? 185.098 152.709 115.223 1.00 140.61 ? 617  ASN A OD1 1 
ATOM   3037 N ND2 . ASN A 1 495  ? 184.849 152.870 117.449 1.00 137.53 ? 617  ASN A ND2 1 
ATOM   3038 N N   . ILE A 1 496  ? 180.703 150.260 114.371 1.00 133.90 ? 618  ILE A N   1 
ATOM   3039 C CA  . ILE A 1 496  ? 179.570 149.338 114.332 1.00 133.72 ? 618  ILE A CA  1 
ATOM   3040 C C   . ILE A 1 496  ? 179.790 148.256 113.278 1.00 134.12 ? 618  ILE A C   1 
ATOM   3041 O O   . ILE A 1 496  ? 179.574 147.062 113.534 1.00 133.74 ? 618  ILE A O   1 
ATOM   3042 C CB  . ILE A 1 496  ? 178.278 150.146 114.092 1.00 131.18 ? 618  ILE A CB  1 
ATOM   3043 C CG1 . ILE A 1 496  ? 178.005 151.049 115.297 1.00 130.48 ? 618  ILE A CG1 1 
ATOM   3044 C CG2 . ILE A 1 496  ? 177.075 149.265 113.808 1.00 130.61 ? 618  ILE A CG2 1 
ATOM   3045 C CD1 . ILE A 1 496  ? 177.758 150.301 116.594 1.00 126.36 ? 618  ILE A CD1 1 
ATOM   3046 N N   . SER A 1 497  ? 180.280 148.650 112.103 1.00 133.14 ? 619  SER A N   1 
ATOM   3047 C CA  . SER A 1 497  ? 180.442 147.723 110.989 1.00 132.13 ? 619  SER A CA  1 
ATOM   3048 C C   . SER A 1 497  ? 181.659 146.825 111.166 1.00 130.99 ? 619  SER A C   1 
ATOM   3049 O O   . SER A 1 497  ? 182.708 147.260 111.651 1.00 129.90 ? 619  SER A O   1 
ATOM   3050 C CB  . SER A 1 497  ? 180.571 148.499 109.682 1.00 129.48 ? 619  SER A CB  1 
ATOM   3051 O OG  . SER A 1 497  ? 180.807 147.630 108.589 1.00 127.01 ? 619  SER A OG  1 
ATOM   3052 N N   . SER A 1 498  ? 181.507 145.565 110.769 1.00 130.48 ? 620  SER A N   1 
ATOM   3053 C CA  . SER A 1 498  ? 182.623 144.642 110.637 1.00 129.37 ? 620  SER A CA  1 
ATOM   3054 C C   . SER A 1 498  ? 183.197 144.633 109.229 1.00 130.52 ? 620  SER A C   1 
ATOM   3055 O O   . SER A 1 498  ? 184.133 143.873 108.959 1.00 129.57 ? 620  SER A O   1 
ATOM   3056 C CB  . SER A 1 498  ? 182.188 143.226 111.028 1.00 124.43 ? 620  SER A CB  1 
ATOM   3057 O OG  . SER A 1 498  ? 181.190 142.738 110.148 1.00 120.56 ? 620  SER A OG  1 
ATOM   3058 N N   . GLY A 1 499  ? 182.657 145.453 108.330 1.00 129.24 ? 621  GLY A N   1 
ATOM   3059 C CA  . GLY A 1 499  ? 183.137 145.517 106.966 1.00 127.85 ? 621  GLY A CA  1 
ATOM   3060 C C   . GLY A 1 499  ? 182.122 145.037 105.949 1.00 128.45 ? 621  GLY A C   1 
ATOM   3061 O O   . GLY A 1 499  ? 181.535 143.963 106.128 1.00 126.79 ? 621  GLY A O   1 
ATOM   3062 N N   . ARG A 1 500  ? 181.919 145.862 104.906 1.00 127.96 ? 622  ARG A N   1 
ATOM   3063 C CA  . ARG A 1 500  ? 181.087 145.598 103.715 1.00 125.37 ? 622  ARG A CA  1 
ATOM   3064 C C   . ARG A 1 500  ? 179.619 145.317 104.042 1.00 121.83 ? 622  ARG A C   1 
ATOM   3065 O O   . ARG A 1 500  ? 179.053 144.326 103.576 1.00 121.80 ? 622  ARG A O   1 
ATOM   3066 C CB  . ARG A 1 500  ? 181.662 144.466 102.850 1.00 127.99 ? 622  ARG A CB  1 
ATOM   3067 C CG  . ARG A 1 500  ? 181.652 144.761 101.359 1.00 130.57 ? 622  ARG A CG  1 
ATOM   3068 C CD  . ARG A 1 500  ? 182.456 143.734 100.580 1.00 136.77 ? 622  ARG A CD  1 
ATOM   3069 N NE  . ARG A 1 500  ? 182.140 143.772 99.157  1.00 141.80 ? 622  ARG A NE  1 
ATOM   3070 C CZ  . ARG A 1 500  ? 182.625 142.927 98.256  1.00 141.65 ? 622  ARG A CZ  1 
ATOM   3071 N NH1 . ARG A 1 500  ? 183.454 141.955 98.597  1.00 141.15 ? 622  ARG A NH1 1 
ATOM   3072 N NH2 . ARG A 1 500  ? 182.263 143.059 96.983  1.00 140.32 ? 622  ARG A NH2 1 
ATOM   3073 N N   . TRP A 1 501  ? 178.996 146.173 104.851 1.00 117.63 ? 623  TRP A N   1 
ATOM   3074 C CA  . TRP A 1 501  ? 177.544 146.142 105.049 1.00 111.79 ? 623  TRP A CA  1 
ATOM   3075 C C   . TRP A 1 501  ? 176.891 147.034 103.987 1.00 107.98 ? 623  TRP A C   1 
ATOM   3076 O O   . TRP A 1 501  ? 176.689 148.234 104.177 1.00 106.86 ? 623  TRP A O   1 
ATOM   3077 C CB  . TRP A 1 501  ? 177.183 146.611 106.455 1.00 109.61 ? 623  TRP A CB  1 
ATOM   3078 C CG  . TRP A 1 501  ? 177.356 145.621 107.599 1.00 112.19 ? 623  TRP A CG  1 
ATOM   3079 C CD1 . TRP A 1 501  ? 178.248 145.726 108.624 1.00 117.49 ? 623  TRP A CD1 1 
ATOM   3080 C CD2 . TRP A 1 501  ? 176.583 144.435 107.866 1.00 112.20 ? 623  TRP A CD2 1 
ATOM   3081 N NE1 . TRP A 1 501  ? 178.107 144.673 109.492 1.00 118.68 ? 623  TRP A NE1 1 
ATOM   3082 C CE2 . TRP A 1 501  ? 177.092 143.866 109.053 1.00 113.01 ? 623  TRP A CE2 1 
ATOM   3083 C CE3 . TRP A 1 501  ? 175.531 143.789 107.209 1.00 111.00 ? 623  TRP A CE3 1 
ATOM   3084 C CZ2 . TRP A 1 501  ? 176.580 142.688 109.597 1.00 112.52 ? 623  TRP A CZ2 1 
ATOM   3085 C CZ3 . TRP A 1 501  ? 175.012 142.621 107.757 1.00 109.97 ? 623  TRP A CZ3 1 
ATOM   3086 C CH2 . TRP A 1 501  ? 175.545 142.082 108.935 1.00 112.05 ? 623  TRP A CH2 1 
ATOM   3087 N N   . VAL A 1 502  ? 176.588 146.435 102.837 1.00 107.23 ? 624  VAL A N   1 
ATOM   3088 C CA  . VAL A 1 502  ? 175.977 147.219 101.750 1.00 104.41 ? 624  VAL A CA  1 
ATOM   3089 C C   . VAL A 1 502  ? 174.452 147.165 101.857 1.00 102.70 ? 624  VAL A C   1 
ATOM   3090 O O   . VAL A 1 502  ? 173.884 146.081 102.088 1.00 102.88 ? 624  VAL A O   1 
ATOM   3091 C CB  . VAL A 1 502  ? 176.491 146.748 100.377 1.00 105.12 ? 624  VAL A CB  1 
ATOM   3092 C CG1 . VAL A 1 502  ? 177.926 147.192 100.204 1.00 109.65 ? 624  VAL A CG1 1 
ATOM   3093 C CG2 . VAL A 1 502  ? 176.487 145.222 100.225 1.00 105.15 ? 624  VAL A CG2 1 
ATOM   3094 N N   . PRO A 1 503  ? 173.746 148.300 101.742 1.00 98.49  ? 625  PRO A N   1 
ATOM   3095 C CA  . PRO A 1 503  ? 172.331 148.338 102.153 1.00 91.68  ? 625  PRO A CA  1 
ATOM   3096 C C   . PRO A 1 503  ? 171.370 147.786 101.111 1.00 91.32  ? 625  PRO A C   1 
ATOM   3097 O O   . PRO A 1 503  ? 171.644 147.803 99.909  1.00 95.06  ? 625  PRO A O   1 
ATOM   3098 C CB  . PRO A 1 503  ? 172.077 149.829 102.403 1.00 85.13  ? 625  PRO A CB  1 
ATOM   3099 C CG  . PRO A 1 503  ? 173.424 150.469 102.430 1.00 89.71  ? 625  PRO A CG  1 
ATOM   3100 C CD  . PRO A 1 503  ? 174.258 149.657 101.506 1.00 95.05  ? 625  PRO A CD  1 
ATOM   3101 N N   . ARG A 1 504  ? 170.233 147.271 101.596 1.00 84.64  ? 626  ARG A N   1 
ATOM   3102 C CA  . ARG A 1 504  ? 169.212 146.662 100.750 1.00 81.47  ? 626  ARG A CA  1 
ATOM   3103 C C   . ARG A 1 504  ? 167.846 147.321 100.878 1.00 77.42  ? 626  ARG A C   1 
ATOM   3104 O O   . ARG A 1 504  ? 167.205 147.592 99.858  1.00 79.32  ? 626  ARG A O   1 
ATOM   3105 C CB  . ARG A 1 504  ? 169.097 145.158 101.049 1.00 84.55  ? 626  ARG A CB  1 
ATOM   3106 C CG  . ARG A 1 504  ? 170.365 144.373 100.751 1.00 91.62  ? 626  ARG A CG  1 
ATOM   3107 C CD  . ARG A 1 504  ? 170.688 144.413 99.269  1.00 93.61  ? 626  ARG A CD  1 
ATOM   3108 N NE  . ARG A 1 504  ? 172.126 144.425 99.027  1.00 96.62  ? 626  ARG A NE  1 
ATOM   3109 C CZ  . ARG A 1 504  ? 172.684 144.481 97.825  1.00 100.06 ? 626  ARG A CZ  1 
ATOM   3110 N NH1 . ARG A 1 504  ? 171.954 144.522 96.724  1.00 100.57 ? 626  ARG A NH1 1 
ATOM   3111 N NH2 . ARG A 1 504  ? 174.011 144.489 97.727  1.00 99.67  ? 626  ARG A NH2 1 
ATOM   3112 N N   . ARG A 1 505  ? 167.358 147.567 102.097 1.00 73.86  ? 627  ARG A N   1 
ATOM   3113 C CA  . ARG A 1 505  ? 166.065 148.213 102.302 1.00 67.28  ? 627  ARG A CA  1 
ATOM   3114 C C   . ARG A 1 505  ? 166.224 149.492 103.110 1.00 68.60  ? 627  ARG A C   1 
ATOM   3115 O O   . ARG A 1 505  ? 167.302 149.786 103.632 1.00 75.45  ? 627  ARG A O   1 
ATOM   3116 C CB  . ARG A 1 505  ? 165.061 147.298 103.009 1.00 65.34  ? 627  ARG A CB  1 
ATOM   3117 C CG  . ARG A 1 505  ? 164.854 145.976 102.313 1.00 68.77  ? 627  ARG A CG  1 
ATOM   3118 C CD  . ARG A 1 505  ? 164.228 146.173 100.942 1.00 67.28  ? 627  ARG A CD  1 
ATOM   3119 N NE  . ARG A 1 505  ? 164.468 145.042 100.054 1.00 67.63  ? 627  ARG A NE  1 
ATOM   3120 C CZ  . ARG A 1 505  ? 164.026 144.963 98.807  1.00 71.30  ? 627  ARG A CZ  1 
ATOM   3121 N NH1 . ARG A 1 505  ? 163.304 145.931 98.269  1.00 74.73  ? 627  ARG A NH1 1 
ATOM   3122 N NH2 . ARG A 1 505  ? 164.317 143.889 98.081  1.00 74.77  ? 627  ARG A NH2 1 
ATOM   3123 N N   . LEU A 1 506  ? 165.129 150.240 103.226 1.00 64.37  ? 628  LEU A N   1 
ATOM   3124 C CA  . LEU A 1 506  ? 165.177 151.602 103.733 1.00 59.97  ? 628  LEU A CA  1 
ATOM   3125 C C   . LEU A 1 506  ? 163.823 152.007 104.296 1.00 64.82  ? 628  LEU A C   1 
ATOM   3126 O O   . LEU A 1 506  ? 162.778 151.726 103.704 1.00 73.80  ? 628  LEU A O   1 
ATOM   3127 C CB  . LEU A 1 506  ? 165.597 152.566 102.617 1.00 62.43  ? 628  LEU A CB  1 
ATOM   3128 C CG  . LEU A 1 506  ? 165.701 154.064 102.884 1.00 67.36  ? 628  LEU A CG  1 
ATOM   3129 C CD1 . LEU A 1 506  ? 166.619 154.338 104.054 1.00 67.67  ? 628  LEU A CD1 1 
ATOM   3130 C CD2 . LEU A 1 506  ? 166.183 154.774 101.640 1.00 70.36  ? 628  LEU A CD2 1 
ATOM   3131 N N   . SER A 1 507  ? 163.855 152.673 105.449 1.00 60.09  ? 629  SER A N   1 
ATOM   3132 C CA  . SER A 1 507  ? 162.671 153.286 106.032 1.00 60.11  ? 629  SER A CA  1 
ATOM   3133 C C   . SER A 1 507  ? 163.113 154.506 106.828 1.00 60.97  ? 629  SER A C   1 
ATOM   3134 O O   . SER A 1 507  ? 164.307 154.781 106.956 1.00 67.00  ? 629  SER A O   1 
ATOM   3135 C CB  . SER A 1 507  ? 161.905 152.297 106.904 1.00 60.62  ? 629  SER A CB  1 
ATOM   3136 O OG  . SER A 1 507  ? 160.615 152.788 107.210 1.00 68.26  ? 629  SER A OG  1 
ATOM   3137 N N   . PHE A 1 508  ? 162.138 155.238 107.364 1.00 57.10  ? 630  PHE A N   1 
ATOM   3138 C CA  . PHE A 1 508  ? 162.402 156.536 107.976 1.00 56.00  ? 630  PHE A CA  1 
ATOM   3139 C C   . PHE A 1 508  ? 161.563 156.716 109.233 1.00 58.93  ? 630  PHE A C   1 
ATOM   3140 O O   . PHE A 1 508  ? 160.348 156.502 109.213 1.00 65.38  ? 630  PHE A O   1 
ATOM   3141 C CB  . PHE A 1 508  ? 162.125 157.665 106.982 1.00 61.66  ? 630  PHE A CB  1 
ATOM   3142 C CG  . PHE A 1 508  ? 162.192 159.036 107.582 1.00 65.68  ? 630  PHE A CG  1 
ATOM   3143 C CD1 . PHE A 1 508  ? 163.382 159.509 108.139 1.00 65.40  ? 630  PHE A CD1 1 
ATOM   3144 C CD2 . PHE A 1 508  ? 161.068 159.859 107.579 1.00 69.86  ? 630  PHE A CD2 1 
ATOM   3145 C CE1 . PHE A 1 508  ? 163.446 160.785 108.701 1.00 64.10  ? 630  PHE A CE1 1 
ATOM   3146 C CE2 . PHE A 1 508  ? 161.121 161.135 108.131 1.00 69.79  ? 630  PHE A CE2 1 
ATOM   3147 C CZ  . PHE A 1 508  ? 162.313 161.595 108.691 1.00 68.66  ? 630  PHE A CZ  1 
ATOM   3148 N N   . ASP A 1 509  ? 162.221 157.118 110.319 1.00 59.53  ? 631  ASP A N   1 
ATOM   3149 C CA  . ASP A 1 509  ? 161.555 157.470 111.568 1.00 59.11  ? 631  ASP A CA  1 
ATOM   3150 C C   . ASP A 1 509  ? 161.224 158.958 111.543 1.00 64.80  ? 631  ASP A C   1 
ATOM   3151 O O   . ASP A 1 509  ? 162.131 159.792 111.517 1.00 70.57  ? 631  ASP A O   1 
ATOM   3152 C CB  . ASP A 1 509  ? 162.483 157.123 112.737 1.00 61.17  ? 631  ASP A CB  1 
ATOM   3153 C CG  . ASP A 1 509  ? 161.776 157.048 114.085 1.00 68.57  ? 631  ASP A CG  1 
ATOM   3154 O OD1 . ASP A 1 509  ? 161.200 158.047 114.557 1.00 70.31  ? 631  ASP A OD1 1 
ATOM   3155 O OD2 . ASP A 1 509  ? 161.809 155.960 114.692 1.00 77.39  ? 631  ASP A OD2 1 
ATOM   3156 N N   . TRP A 1 510  ? 159.939 159.305 111.570 1.00 65.76  ? 632  TRP A N   1 
ATOM   3157 C CA  . TRP A 1 510  ? 159.570 160.707 111.422 1.00 62.45  ? 632  TRP A CA  1 
ATOM   3158 C C   . TRP A 1 510  ? 159.513 161.467 112.737 1.00 65.59  ? 632  TRP A C   1 
ATOM   3159 O O   . TRP A 1 510  ? 159.238 162.671 112.721 1.00 70.61  ? 632  TRP A O   1 
ATOM   3160 C CB  . TRP A 1 510  ? 158.229 160.848 110.689 1.00 59.82  ? 632  TRP A CB  1 
ATOM   3161 C CG  . TRP A 1 510  ? 157.065 160.191 111.352 1.00 60.86  ? 632  TRP A CG  1 
ATOM   3162 C CD1 . TRP A 1 510  ? 156.215 160.751 112.257 1.00 64.52  ? 632  TRP A CD1 1 
ATOM   3163 C CD2 . TRP A 1 510  ? 156.602 158.858 111.137 1.00 58.87  ? 632  TRP A CD2 1 
ATOM   3164 N NE1 . TRP A 1 510  ? 155.260 159.843 112.636 1.00 63.99  ? 632  TRP A NE1 1 
ATOM   3165 C CE2 . TRP A 1 510  ? 155.473 158.673 111.960 1.00 58.97  ? 632  TRP A CE2 1 
ATOM   3166 C CE3 . TRP A 1 510  ? 157.036 157.799 110.335 1.00 57.51  ? 632  TRP A CE3 1 
ATOM   3167 C CZ2 . TRP A 1 510  ? 154.775 157.467 112.005 1.00 56.72  ? 632  TRP A CZ2 1 
ATOM   3168 C CZ3 . TRP A 1 510  ? 156.340 156.609 110.374 1.00 55.96  ? 632  TRP A CZ3 1 
ATOM   3169 C CH2 . TRP A 1 510  ? 155.221 156.450 111.206 1.00 57.05  ? 632  TRP A CH2 1 
ATOM   3170 N N   . LEU A 1 511  ? 159.764 160.812 113.866 1.00 65.21  ? 633  LEU A N   1 
ATOM   3171 C CA  . LEU A 1 511  ? 159.747 161.523 115.137 1.00 66.70  ? 633  LEU A CA  1 
ATOM   3172 C C   . LEU A 1 511  ? 161.140 161.792 115.679 1.00 71.27  ? 633  LEU A C   1 
ATOM   3173 O O   . LEU A 1 511  ? 161.432 162.924 116.080 1.00 77.99  ? 633  LEU A O   1 
ATOM   3174 C CB  . LEU A 1 511  ? 158.941 160.741 116.176 1.00 67.55  ? 633  LEU A CB  1 
ATOM   3175 C CG  . LEU A 1 511  ? 157.444 160.593 115.898 1.00 67.06  ? 633  LEU A CG  1 
ATOM   3176 C CD1 . LEU A 1 511  ? 156.771 159.904 117.051 1.00 67.50  ? 633  LEU A CD1 1 
ATOM   3177 C CD2 . LEU A 1 511  ? 156.793 161.921 115.647 1.00 62.60  ? 633  LEU A CD2 1 
ATOM   3178 N N   . HIS A 1 512  ? 162.007 160.785 115.696 1.00 69.08  ? 634  HIS A N   1 
ATOM   3179 C CA  . HIS A 1 512  ? 163.364 160.934 116.193 1.00 70.45  ? 634  HIS A CA  1 
ATOM   3180 C C   . HIS A 1 512  ? 164.354 161.267 115.088 1.00 68.10  ? 634  HIS A C   1 
ATOM   3181 O O   . HIS A 1 512  ? 165.555 161.372 115.379 1.00 68.99  ? 634  HIS A O   1 
ATOM   3182 C CB  . HIS A 1 512  ? 163.797 159.657 116.919 1.00 73.38  ? 634  HIS A CB  1 
ATOM   3183 C CG  . HIS A 1 512  ? 162.782 159.144 117.894 1.00 78.43  ? 634  HIS A CG  1 
ATOM   3184 N ND1 . HIS A 1 512  ? 162.072 159.970 118.738 1.00 81.41  ? 634  HIS A ND1 1 
ATOM   3185 C CD2 . HIS A 1 512  ? 162.346 157.887 118.145 1.00 78.75  ? 634  HIS A CD2 1 
ATOM   3186 C CE1 . HIS A 1 512  ? 161.249 159.244 119.473 1.00 82.95  ? 634  HIS A CE1 1 
ATOM   3187 N NE2 . HIS A 1 512  ? 161.396 157.976 119.132 1.00 81.72  ? 634  HIS A NE2 1 
ATOM   3188 N N   . HIS A 1 513  ? 163.861 161.424 113.842 1.00 64.75  ? 635  HIS A N   1 
ATOM   3189 C CA  . HIS A 1 513  ? 164.600 161.820 112.625 1.00 66.13  ? 635  HIS A CA  1 
ATOM   3190 C C   . HIS A 1 513  ? 165.740 160.856 112.303 1.00 66.15  ? 635  HIS A C   1 
ATOM   3191 O O   . HIS A 1 513  ? 166.873 161.253 112.029 1.00 70.88  ? 635  HIS A O   1 
ATOM   3192 C CB  . HIS A 1 513  ? 165.084 163.270 112.703 1.00 70.10  ? 635  HIS A CB  1 
ATOM   3193 C CG  . HIS A 1 513  ? 163.972 164.256 112.853 1.00 74.58  ? 635  HIS A CG  1 
ATOM   3194 N ND1 . HIS A 1 513  ? 163.479 164.986 111.795 1.00 78.39  ? 635  HIS A ND1 1 
ATOM   3195 C CD2 . HIS A 1 513  ? 163.246 164.622 113.935 1.00 75.52  ? 635  HIS A CD2 1 
ATOM   3196 C CE1 . HIS A 1 513  ? 162.500 165.764 112.220 1.00 80.79  ? 635  HIS A CE1 1 
ATOM   3197 N NE2 . HIS A 1 513  ? 162.337 165.560 113.514 1.00 80.54  ? 635  HIS A NE2 1 
ATOM   3198 N N   . ARG A 1 514  ? 165.417 159.573 112.345 1.00 63.48  ? 636  ARG A N   1 
ATOM   3199 C CA  . ARG A 1 514  ? 166.371 158.494 112.196 1.00 59.91  ? 636  ARG A CA  1 
ATOM   3200 C C   . ARG A 1 514  ? 166.079 157.804 110.871 1.00 59.65  ? 636  ARG A C   1 
ATOM   3201 O O   . ARG A 1 514  ? 164.929 157.745 110.436 1.00 64.94  ? 636  ARG A O   1 
ATOM   3202 C CB  . ARG A 1 514  ? 166.218 157.484 113.340 1.00 63.85  ? 636  ARG A CB  1 
ATOM   3203 C CG  . ARG A 1 514  ? 166.454 158.006 114.756 1.00 66.84  ? 636  ARG A CG  1 
ATOM   3204 C CD  . ARG A 1 514  ? 167.868 158.430 115.074 1.00 67.79  ? 636  ARG A CD  1 
ATOM   3205 N NE  . ARG A 1 514  ? 168.811 157.319 115.022 1.00 66.23  ? 636  ARG A NE  1 
ATOM   3206 C CZ  . ARG A 1 514  ? 170.126 157.458 114.958 1.00 69.73  ? 636  ARG A CZ  1 
ATOM   3207 N NH1 . ARG A 1 514  ? 170.691 158.653 114.972 1.00 70.51  ? 636  ARG A NH1 1 
ATOM   3208 N NH2 . ARG A 1 514  ? 170.892 156.372 114.915 1.00 73.53  ? 636  ARG A NH2 1 
ATOM   3209 N N   . LEU A 1 515  ? 167.115 157.290 110.221 1.00 59.15  ? 637  LEU A N   1 
ATOM   3210 C CA  . LEU A 1 515  ? 166.944 156.459 109.034 1.00 58.27  ? 637  LEU A CA  1 
ATOM   3211 C C   . LEU A 1 515  ? 167.246 155.019 109.410 1.00 63.50  ? 637  LEU A C   1 
ATOM   3212 O O   . LEU A 1 515  ? 168.328 154.725 109.928 1.00 70.56  ? 637  LEU A O   1 
ATOM   3213 C CB  . LEU A 1 515  ? 167.844 156.909 107.886 1.00 60.21  ? 637  LEU A CB  1 
ATOM   3214 C CG  . LEU A 1 515  ? 167.328 158.037 106.998 1.00 66.84  ? 637  LEU A CG  1 
ATOM   3215 C CD1 . LEU A 1 515  ? 168.429 158.479 106.059 1.00 71.72  ? 637  LEU A CD1 1 
ATOM   3216 C CD2 . LEU A 1 515  ? 166.100 157.602 106.220 1.00 67.52  ? 637  LEU A CD2 1 
ATOM   3217 N N   . TYR A 1 516  ? 166.297 154.129 109.152 1.00 59.89  ? 638  TYR A N   1 
ATOM   3218 C CA  . TYR A 1 516  ? 166.430 152.726 109.503 1.00 54.30  ? 638  TYR A CA  1 
ATOM   3219 C C   . TYR A 1 516  ? 166.696 151.920 108.242 1.00 58.80  ? 638  TYR A C   1 
ATOM   3220 O O   . TYR A 1 516  ? 166.008 152.085 107.231 1.00 66.85  ? 638  TYR A O   1 
ATOM   3221 C CB  . TYR A 1 516  ? 165.178 152.205 110.207 1.00 52.99  ? 638  TYR A CB  1 
ATOM   3222 C CG  . TYR A 1 516  ? 165.100 152.550 111.679 1.00 52.89  ? 638  TYR A CG  1 
ATOM   3223 C CD1 . TYR A 1 516  ? 164.773 153.845 112.095 1.00 55.37  ? 638  TYR A CD1 1 
ATOM   3224 C CD2 . TYR A 1 516  ? 165.377 151.585 112.652 1.00 52.84  ? 638  TYR A CD2 1 
ATOM   3225 C CE1 . TYR A 1 516  ? 164.700 154.165 113.444 1.00 56.95  ? 638  TYR A CE1 1 
ATOM   3226 C CE2 . TYR A 1 516  ? 165.303 151.895 114.009 1.00 55.54  ? 638  TYR A CE2 1 
ATOM   3227 C CZ  . TYR A 1 516  ? 164.973 153.190 114.388 1.00 59.73  ? 638  TYR A CZ  1 
ATOM   3228 O OH  . TYR A 1 516  ? 164.906 153.520 115.720 1.00 65.24  ? 638  TYR A OH  1 
ATOM   3229 N N   . PHE A 1 517  ? 167.695 151.050 108.306 1.00 56.15  ? 639  PHE A N   1 
ATOM   3230 C CA  . PHE A 1 517  ? 168.215 150.373 107.131 1.00 58.20  ? 639  PHE A CA  1 
ATOM   3231 C C   . PHE A 1 517  ? 168.091 148.868 107.285 1.00 61.27  ? 639  PHE A C   1 
ATOM   3232 O O   . PHE A 1 517  ? 167.569 148.367 108.277 1.00 65.09  ? 639  PHE A O   1 
ATOM   3233 C CB  . PHE A 1 517  ? 169.677 150.741 106.898 1.00 62.00  ? 639  PHE A CB  1 
ATOM   3234 C CG  . PHE A 1 517  ? 169.869 152.008 106.140 1.00 62.59  ? 639  PHE A CG  1 
ATOM   3235 C CD1 . PHE A 1 517  ? 169.713 153.241 106.770 1.00 63.03  ? 639  PHE A CD1 1 
ATOM   3236 C CD2 . PHE A 1 517  ? 170.229 151.969 104.794 1.00 69.51  ? 639  PHE A CD2 1 
ATOM   3237 C CE1 . PHE A 1 517  ? 169.893 154.424 106.059 1.00 71.25  ? 639  PHE A CE1 1 
ATOM   3238 C CE2 . PHE A 1 517  ? 170.422 153.145 104.080 1.00 76.55  ? 639  PHE A CE2 1 
ATOM   3239 C CZ  . PHE A 1 517  ? 170.248 154.370 104.715 1.00 77.99  ? 639  PHE A CZ  1 
ATOM   3240 N N   . ALA A 1 518  ? 168.570 148.158 106.267 1.00 63.15  ? 640  ALA A N   1 
ATOM   3241 C CA  . ALA A 1 518  ? 168.782 146.716 106.305 1.00 69.78  ? 640  ALA A CA  1 
ATOM   3242 C C   . ALA A 1 518  ? 169.898 146.401 105.322 1.00 79.42  ? 640  ALA A C   1 
ATOM   3243 O O   . ALA A 1 518  ? 169.727 146.593 104.116 1.00 79.95  ? 640  ALA A O   1 
ATOM   3244 C CB  . ALA A 1 518  ? 167.510 145.948 105.939 1.00 66.91  ? 640  ALA A CB  1 
ATOM   3245 N N   . MET A 1 519  ? 171.037 145.928 105.826 1.00 84.95  ? 641  MET A N   1 
ATOM   3246 C CA  . MET A 1 519  ? 172.209 145.774 104.980 1.00 91.87  ? 641  MET A CA  1 
ATOM   3247 C C   . MET A 1 519  ? 172.468 144.310 104.658 1.00 96.97  ? 641  MET A C   1 
ATOM   3248 O O   . MET A 1 519  ? 171.764 143.415 105.129 1.00 98.01  ? 641  MET A O   1 
ATOM   3249 C CB  . MET A 1 519  ? 173.486 146.324 105.611 1.00 95.68  ? 641  MET A CB  1 
ATOM   3250 C CG  . MET A 1 519  ? 173.667 147.807 105.632 1.00 95.07  ? 641  MET A CG  1 
ATOM   3251 S SD  . MET A 1 519  ? 172.557 148.390 106.883 1.00 91.73  ? 641  MET A SD  1 
ATOM   3252 C CE  . MET A 1 519  ? 173.550 147.799 108.239 1.00 92.17  ? 641  MET A CE  1 
ATOM   3253 N N   . GLU A 1 520  ? 173.511 144.083 103.859 1.00 103.56 ? 642  GLU A N   1 
ATOM   3254 C CA  . GLU A 1 520  ? 173.978 142.753 103.491 1.00 108.59 ? 642  GLU A CA  1 
ATOM   3255 C C   . GLU A 1 520  ? 175.481 142.659 103.706 1.00 112.98 ? 642  GLU A C   1 
ATOM   3256 O O   . GLU A 1 520  ? 176.235 143.485 103.185 1.00 112.84 ? 642  GLU A O   1 
ATOM   3257 C CB  . GLU A 1 520  ? 173.646 142.442 102.027 1.00 107.41 ? 642  GLU A CB  1 
ATOM   3258 C CG  . GLU A 1 520  ? 174.222 141.123 101.518 1.00 110.04 ? 642  GLU A CG  1 
ATOM   3259 C CD  . GLU A 1 520  ? 173.906 140.859 100.060 1.00 111.42 ? 642  GLU A CD  1 
ATOM   3260 O OE1 . GLU A 1 520  ? 173.567 141.815 99.336  1.00 111.91 ? 642  GLU A OE1 1 
ATOM   3261 O OE2 . GLU A 1 520  ? 173.973 139.685 99.641  1.00 111.07 ? 642  GLU A OE2 1 
ATOM   3262 N N   . SER A 1 521  ? 175.914 141.654 104.469 1.00 115.64 ? 643  SER A N   1 
ATOM   3263 C CA  . SER A 1 521  ? 177.319 141.268 104.512 1.00 119.34 ? 643  SER A CA  1 
ATOM   3264 C C   . SER A 1 521  ? 177.473 139.910 103.846 1.00 124.09 ? 643  SER A C   1 
ATOM   3265 O O   . SER A 1 521  ? 176.679 139.003 104.141 1.00 123.80 ? 643  SER A O   1 
ATOM   3266 C CB  . SER A 1 521  ? 177.845 141.215 105.944 1.00 117.92 ? 643  SER A CB  1 
ATOM   3267 O OG  . SER A 1 521  ? 179.210 140.837 105.973 1.00 120.58 ? 643  SER A OG  1 
ATOM   3268 N N   . PRO A 1 522  ? 178.436 139.722 102.941 1.00 127.05 ? 644  PRO A N   1 
ATOM   3269 C CA  . PRO A 1 522  ? 178.663 138.382 102.380 1.00 126.75 ? 644  PRO A CA  1 
ATOM   3270 C C   . PRO A 1 522  ? 179.349 137.463 103.385 1.00 125.59 ? 644  PRO A C   1 
ATOM   3271 O O   . PRO A 1 522  ? 180.539 137.598 103.674 1.00 123.41 ? 644  PRO A O   1 
ATOM   3272 C CB  . PRO A 1 522  ? 179.545 138.650 101.154 1.00 126.97 ? 644  PRO A CB  1 
ATOM   3273 C CG  . PRO A 1 522  ? 180.141 140.001 101.373 1.00 128.41 ? 644  PRO A CG  1 
ATOM   3274 C CD  . PRO A 1 522  ? 179.177 140.770 102.214 1.00 124.63 ? 644  PRO A CD  1 
ATOM   3275 N N   . GLU A 1 523  ? 178.577 136.523 103.922 1.00 125.56 ? 645  GLU A N   1 
ATOM   3276 C CA  . GLU A 1 523  ? 179.086 135.589 104.917 1.00 125.76 ? 645  GLU A CA  1 
ATOM   3277 C C   . GLU A 1 523  ? 178.560 134.181 104.658 1.00 124.42 ? 645  GLU A C   1 
ATOM   3278 O O   . GLU A 1 523  ? 177.427 133.857 105.010 1.00 120.68 ? 645  GLU A O   1 
ATOM   3279 C CB  . GLU A 1 523  ? 178.705 136.041 106.329 1.00 124.77 ? 645  GLU A CB  1 
ATOM   3280 C CG  . GLU A 1 523  ? 179.709 136.990 106.968 1.00 124.64 ? 645  GLU A CG  1 
ATOM   3281 C CD  . GLU A 1 523  ? 179.149 137.698 108.185 1.00 124.40 ? 645  GLU A CD  1 
ATOM   3282 O OE1 . GLU A 1 523  ? 178.095 137.267 108.692 1.00 122.81 ? 645  GLU A OE1 1 
ATOM   3283 O OE2 . GLU A 1 523  ? 179.763 138.689 108.634 1.00 121.36 ? 645  GLU A OE2 1 
ATOM   3284 N N   . SER A 1 528  ? 174.269 137.119 106.085 1.00 102.86 ? 650  SER A N   1 
ATOM   3285 C CA  . SER A 1 528  ? 173.715 137.680 107.311 1.00 107.29 ? 650  SER A CA  1 
ATOM   3286 C C   . SER A 1 528  ? 173.213 139.097 107.080 1.00 109.68 ? 650  SER A C   1 
ATOM   3287 O O   . SER A 1 528  ? 173.773 139.857 106.289 1.00 106.43 ? 650  SER A O   1 
ATOM   3288 C CB  . SER A 1 528  ? 174.750 137.660 108.435 1.00 103.32 ? 650  SER A CB  1 
ATOM   3289 O OG  . SER A 1 528  ? 174.209 138.195 109.630 1.00 102.69 ? 650  SER A OG  1 
ATOM   3290 N N   . PHE A 1 529  ? 172.157 139.444 107.805 1.00 106.07 ? 651  PHE A N   1 
ATOM   3291 C CA  . PHE A 1 529  ? 171.269 140.534 107.442 1.00 92.95  ? 651  PHE A CA  1 
ATOM   3292 C C   . PHE A 1 529  ? 170.933 141.295 108.714 1.00 90.14  ? 651  PHE A C   1 
ATOM   3293 O O   . PHE A 1 529  ? 170.423 140.703 109.669 1.00 91.51  ? 651  PHE A O   1 
ATOM   3294 C CB  . PHE A 1 529  ? 170.020 139.936 106.791 1.00 94.50  ? 651  PHE A CB  1 
ATOM   3295 C CG  . PHE A 1 529  ? 170.214 139.549 105.346 1.00 99.32  ? 651  PHE A CG  1 
ATOM   3296 C CD1 . PHE A 1 529  ? 169.529 138.452 104.811 1.00 100.27 ? 651  PHE A CD1 1 
ATOM   3297 C CD2 . PHE A 1 529  ? 171.039 140.296 104.512 1.00 98.51  ? 651  PHE A CD2 1 
ATOM   3298 C CE1 . PHE A 1 529  ? 169.727 138.068 103.473 1.00 99.22  ? 651  PHE A CE1 1 
ATOM   3299 C CE2 . PHE A 1 529  ? 171.210 139.940 103.168 1.00 98.44  ? 651  PHE A CE2 1 
ATOM   3300 C CZ  . PHE A 1 529  ? 170.549 138.831 102.653 1.00 98.71  ? 651  PHE A CZ  1 
ATOM   3301 N N   . GLN A 1 530  ? 171.223 142.594 108.740 1.00 89.98  ? 652  GLN A N   1 
ATOM   3302 C CA  . GLN A 1 530  ? 171.146 143.357 109.978 1.00 87.32  ? 652  GLN A CA  1 
ATOM   3303 C C   . GLN A 1 530  ? 170.493 144.714 109.758 1.00 89.58  ? 652  GLN A C   1 
ATOM   3304 O O   . GLN A 1 530  ? 170.898 145.492 108.890 1.00 93.73  ? 652  GLN A O   1 
ATOM   3305 C CB  . GLN A 1 530  ? 172.541 143.540 110.599 1.00 88.74  ? 652  GLN A CB  1 
ATOM   3306 C CG  . GLN A 1 530  ? 172.562 144.265 111.944 1.00 91.94  ? 652  GLN A CG  1 
ATOM   3307 C CD  . GLN A 1 530  ? 171.889 143.483 113.056 1.00 100.95 ? 652  GLN A CD  1 
ATOM   3308 O OE1 . GLN A 1 530  ? 172.048 142.269 113.160 1.00 102.50 ? 652  GLN A OE1 1 
ATOM   3309 N NE2 . GLN A 1 530  ? 171.145 144.182 113.905 1.00 101.60 ? 652  GLN A NE2 1 
ATOM   3310 N N   . ILE A 1 531  ? 169.474 144.980 110.569 1.00 86.03  ? 653  ILE A N   1 
ATOM   3311 C CA  . ILE A 1 531  ? 168.797 146.269 110.642 1.00 87.23  ? 653  ILE A CA  1 
ATOM   3312 C C   . ILE A 1 531  ? 169.582 147.158 111.599 1.00 87.42  ? 653  ILE A C   1 
ATOM   3313 O O   . ILE A 1 531  ? 169.927 146.727 112.704 1.00 95.96  ? 653  ILE A O   1 
ATOM   3314 C CB  . ILE A 1 531  ? 167.341 146.084 111.112 1.00 84.49  ? 653  ILE A CB  1 
ATOM   3315 C CG1 . ILE A 1 531  ? 166.556 145.245 110.105 1.00 86.37  ? 653  ILE A CG1 1 
ATOM   3316 C CG2 . ILE A 1 531  ? 166.621 147.408 111.353 1.00 74.28  ? 653  ILE A CG2 1 
ATOM   3317 C CD1 . ILE A 1 531  ? 165.239 144.744 110.635 1.00 78.12  ? 653  ILE A CD1 1 
ATOM   3318 N N   . ILE A 1 532  ? 169.915 148.376 111.171 1.00 81.07  ? 654  ILE A N   1 
ATOM   3319 C CA  . ILE A 1 532  ? 170.482 149.387 112.059 1.00 85.38  ? 654  ILE A CA  1 
ATOM   3320 C C   . ILE A 1 532  ? 169.635 150.646 111.976 1.00 91.63  ? 654  ILE A C   1 
ATOM   3321 O O   . ILE A 1 532  ? 168.761 150.762 111.109 1.00 103.63 ? 654  ILE A O   1 
ATOM   3322 C CB  . ILE A 1 532  ? 171.948 149.737 111.729 1.00 90.52  ? 654  ILE A CB  1 
ATOM   3323 C CG1 . ILE A 1 532  ? 172.044 150.464 110.384 1.00 92.03  ? 654  ILE A CG1 1 
ATOM   3324 C CG2 . ILE A 1 532  ? 172.882 148.529 111.888 1.00 87.26  ? 654  ILE A CG2 1 
ATOM   3325 C CD1 . ILE A 1 532  ? 173.374 151.153 110.161 1.00 91.72  ? 654  ILE A CD1 1 
ATOM   3326 N N   . SER A 1 533  ? 169.888 151.570 112.892 1.00 87.13  ? 655  SER A N   1 
ATOM   3327 C CA  . SER A 1 533  ? 169.379 152.930 112.809 1.00 83.68  ? 655  SER A CA  1 
ATOM   3328 C C   . SER A 1 533  ? 170.552 153.864 112.562 1.00 85.43  ? 655  SER A C   1 
ATOM   3329 O O   . SER A 1 533  ? 171.627 153.670 113.132 1.00 95.03  ? 655  SER A O   1 
ATOM   3330 C CB  . SER A 1 533  ? 168.662 153.327 114.093 1.00 88.47  ? 655  SER A CB  1 
ATOM   3331 O OG  . SER A 1 533  ? 168.212 154.668 114.022 1.00 102.87 ? 655  SER A OG  1 
ATOM   3332 N N   . THR A 1 534  ? 170.354 154.872 111.723 1.00 91.66  ? 656  THR A N   1 
ATOM   3333 C CA  . THR A 1 534  ? 171.356 155.907 111.523 1.00 97.68  ? 656  THR A CA  1 
ATOM   3334 C C   . THR A 1 534  ? 170.672 157.262 111.373 1.00 100.60 ? 656  THR A C   1 
ATOM   3335 O O   . THR A 1 534  ? 169.454 157.362 111.210 1.00 108.76 ? 656  THR A O   1 
ATOM   3336 C CB  . THR A 1 534  ? 172.253 155.602 110.316 1.00 99.33  ? 656  THR A CB  1 
ATOM   3337 O OG1 . THR A 1 534  ? 173.391 156.474 110.344 1.00 106.03 ? 656  THR A OG1 1 
ATOM   3338 C CG2 . THR A 1 534  ? 171.522 155.824 109.023 1.00 98.74  ? 656  THR A CG2 1 
ATOM   3339 N N   . ASP A 1 535  ? 171.473 158.317 111.454 1.00 99.69  ? 657  ASP A N   1 
ATOM   3340 C CA  . ASP A 1 535  ? 170.959 159.677 111.481 1.00 104.94 ? 657  ASP A CA  1 
ATOM   3341 C C   . ASP A 1 535  ? 170.821 160.148 110.023 1.00 108.18 ? 657  ASP A C   1 
ATOM   3342 O O   . ASP A 1 535  ? 171.222 159.448 109.089 1.00 109.47 ? 657  ASP A O   1 
ATOM   3343 C CB  . ASP A 1 535  ? 171.899 160.519 112.365 1.00 115.00 ? 657  ASP A CB  1 
ATOM   3344 C CG  . ASP A 1 535  ? 171.348 161.886 112.732 1.00 121.26 ? 657  ASP A CG  1 
ATOM   3345 O OD1 . ASP A 1 535  ? 170.439 161.966 113.582 1.00 118.40 ? 657  ASP A OD1 1 
ATOM   3346 O OD2 . ASP A 1 535  ? 171.822 162.877 112.147 1.00 123.89 ? 657  ASP A OD2 1 
ATOM   3347 N N   . LEU A 1 536  ? 170.253 161.341 109.797 1.00 104.76 ? 658  LEU A N   1 
ATOM   3348 C CA  . LEU A 1 536  ? 170.060 161.894 108.462 1.00 101.62 ? 658  LEU A CA  1 
ATOM   3349 C C   . LEU A 1 536  ? 171.348 162.381 107.808 1.00 104.88 ? 658  LEU A C   1 
ATOM   3350 O O   . LEU A 1 536  ? 171.329 162.684 106.610 1.00 102.57 ? 658  LEU A O   1 
ATOM   3351 C CB  . LEU A 1 536  ? 169.068 163.056 108.521 1.00 100.63 ? 658  LEU A CB  1 
ATOM   3352 C CG  . LEU A 1 536  ? 167.670 162.816 109.093 1.00 99.39  ? 658  LEU A CG  1 
ATOM   3353 C CD1 . LEU A 1 536  ? 166.789 164.044 108.884 1.00 97.24  ? 658  LEU A CD1 1 
ATOM   3354 C CD2 . LEU A 1 536  ? 167.042 161.585 108.483 1.00 100.62 ? 658  LEU A CD2 1 
ATOM   3355 N N   . LEU A 1 537  ? 172.441 162.505 108.555 1.00 107.20 ? 659  LEU A N   1 
ATOM   3356 C CA  . LEU A 1 537  ? 173.769 162.691 107.995 1.00 106.77 ? 659  LEU A CA  1 
ATOM   3357 C C   . LEU A 1 537  ? 174.545 161.384 107.933 1.00 109.56 ? 659  LEU A C   1 
ATOM   3358 O O   . LEU A 1 537  ? 175.655 161.360 107.396 1.00 109.88 ? 659  LEU A O   1 
ATOM   3359 C CB  . LEU A 1 537  ? 174.567 163.722 108.810 1.00 110.86 ? 659  LEU A CB  1 
ATOM   3360 C CG  . LEU A 1 537  ? 174.371 165.246 108.712 1.00 116.82 ? 659  LEU A CG  1 
ATOM   3361 C CD1 . LEU A 1 537  ? 173.076 165.781 109.329 1.00 114.04 ? 659  LEU A CD1 1 
ATOM   3362 C CD2 . LEU A 1 537  ? 175.574 165.947 109.329 1.00 119.64 ? 659  LEU A CD2 1 
ATOM   3363 N N   . GLY A 1 538  ? 173.980 160.297 108.459 1.00 112.03 ? 660  GLY A N   1 
ATOM   3364 C CA  . GLY A 1 538  ? 174.674 159.028 108.532 1.00 107.30 ? 660  GLY A CA  1 
ATOM   3365 C C   . GLY A 1 538  ? 175.745 158.951 109.595 1.00 109.79 ? 660  GLY A C   1 
ATOM   3366 O O   . GLY A 1 538  ? 176.713 158.204 109.420 1.00 108.32 ? 660  GLY A O   1 
ATOM   3367 N N   . GLU A 1 539  ? 175.604 159.696 110.694 1.00 112.67 ? 661  GLU A N   1 
ATOM   3368 C CA  . GLU A 1 539  ? 176.733 159.903 111.596 1.00 117.46 ? 661  GLU A CA  1 
ATOM   3369 C C   . GLU A 1 539  ? 176.722 158.927 112.770 1.00 117.64 ? 661  GLU A C   1 
ATOM   3370 O O   . GLU A 1 539  ? 177.767 158.675 113.382 1.00 122.25 ? 661  GLU A O   1 
ATOM   3371 C CB  . GLU A 1 539  ? 176.744 161.354 112.092 1.00 121.92 ? 661  GLU A CB  1 
ATOM   3372 C CG  . GLU A 1 539  ? 175.511 161.783 112.885 1.00 128.72 ? 661  GLU A CG  1 
ATOM   3373 C CD  . GLU A 1 539  ? 175.567 163.237 113.318 1.00 138.69 ? 661  GLU A CD  1 
ATOM   3374 O OE1 . GLU A 1 539  ? 176.560 163.921 112.992 1.00 139.46 ? 661  GLU A OE1 1 
ATOM   3375 O OE2 . GLU A 1 539  ? 174.619 163.694 113.991 1.00 141.52 ? 661  GLU A OE2 1 
ATOM   3376 N N   . SER A 1 540  ? 175.562 158.368 113.108 1.00 111.01 ? 662  SER A N   1 
ATOM   3377 C CA  . SER A 1 540  ? 175.401 157.616 114.347 1.00 106.32 ? 662  SER A CA  1 
ATOM   3378 C C   . SER A 1 540  ? 174.707 156.290 114.081 1.00 100.88 ? 662  SER A C   1 
ATOM   3379 O O   . SER A 1 540  ? 173.478 156.205 114.166 1.00 104.54 ? 662  SER A O   1 
ATOM   3380 C CB  . SER A 1 540  ? 174.606 158.424 115.370 1.00 104.37 ? 662  SER A CB  1 
ATOM   3381 O OG  . SER A 1 540  ? 174.340 157.648 116.524 1.00 99.14  ? 662  SER A OG  1 
ATOM   3382 N N   . ALA A 1 541  ? 175.490 155.253 113.808 1.00 95.74  ? 663  ALA A N   1 
ATOM   3383 C CA  . ALA A 1 541  ? 174.970 153.909 113.603 1.00 94.12  ? 663  ALA A CA  1 
ATOM   3384 C C   . ALA A 1 541  ? 174.728 153.262 114.960 1.00 95.06  ? 663  ALA A C   1 
ATOM   3385 O O   . ALA A 1 541  ? 175.592 153.321 115.840 1.00 100.49 ? 663  ALA A O   1 
ATOM   3386 C CB  . ALA A 1 541  ? 175.934 153.069 112.767 1.00 90.58  ? 663  ALA A CB  1 
ATOM   3387 N N   . GLN A 1 542  ? 173.539 152.687 115.144 1.00 90.04  ? 664  GLN A N   1 
ATOM   3388 C CA  . GLN A 1 542  ? 173.214 151.860 116.307 1.00 89.43  ? 664  GLN A CA  1 
ATOM   3389 C C   . GLN A 1 542  ? 172.701 150.520 115.793 1.00 90.12  ? 664  GLN A C   1 
ATOM   3390 O O   . GLN A 1 542  ? 171.729 150.480 115.035 1.00 98.32  ? 664  GLN A O   1 
ATOM   3391 C CB  . GLN A 1 542  ? 172.172 152.514 117.218 1.00 87.19  ? 664  GLN A CB  1 
ATOM   3392 C CG  . GLN A 1 542  ? 172.324 154.000 117.482 1.00 95.74  ? 664  GLN A CG  1 
ATOM   3393 C CD  . GLN A 1 542  ? 171.425 154.473 118.604 1.00 106.14 ? 664  GLN A CD  1 
ATOM   3394 O OE1 . GLN A 1 542  ? 170.891 153.667 119.363 1.00 110.13 ? 664  GLN A OE1 1 
ATOM   3395 N NE2 . GLN A 1 542  ? 171.251 155.785 118.712 1.00 103.91 ? 664  GLN A NE2 1 
ATOM   3396 N N   . LYS A 1 543  ? 173.341 149.429 116.209 1.00 89.27  ? 665  LYS A N   1 
ATOM   3397 C CA  . LYS A 1 543  ? 172.836 148.100 115.892 1.00 90.15  ? 665  LYS A CA  1 
ATOM   3398 C C   . LYS A 1 543  ? 171.595 147.790 116.716 1.00 96.67  ? 665  LYS A C   1 
ATOM   3399 O O   . LYS A 1 543  ? 171.601 147.882 117.946 1.00 98.50  ? 665  LYS A O   1 
ATOM   3400 C CB  . LYS A 1 543  ? 173.901 147.035 116.153 1.00 100.53 ? 665  LYS A CB  1 
ATOM   3401 C CG  . LYS A 1 543  ? 174.659 146.584 114.919 1.00 103.29 ? 665  LYS A CG  1 
ATOM   3402 C CD  . LYS A 1 543  ? 175.382 145.260 115.151 1.00 107.92 ? 665  LYS A CD  1 
ATOM   3403 C CE  . LYS A 1 543  ? 176.393 145.359 116.288 1.00 107.05 ? 665  LYS A CE  1 
ATOM   3404 N NZ  . LYS A 1 543  ? 177.539 144.428 116.095 1.00 101.00 ? 665  LYS A NZ  1 
ATOM   3405 N N   . VAL A 1 544  ? 170.524 147.421 116.024 1.00 96.62  ? 666  VAL A N   1 
ATOM   3406 C CA  . VAL A 1 544  ? 169.244 147.111 116.646 1.00 96.66  ? 666  VAL A CA  1 
ATOM   3407 C C   . VAL A 1 544  ? 168.858 145.680 116.258 1.00 93.75  ? 666  VAL A C   1 
ATOM   3408 O O   . VAL A 1 544  ? 169.089 145.241 115.122 1.00 91.14  ? 666  VAL A O   1 
ATOM   3409 C CB  . VAL A 1 544  ? 168.189 148.192 116.309 1.00 94.05  ? 666  VAL A CB  1 
ATOM   3410 C CG1 . VAL A 1 544  ? 167.830 148.291 114.836 1.00 90.59  ? 666  VAL A CG1 1 
ATOM   3411 C CG2 . VAL A 1 544  ? 166.930 148.002 117.103 1.00 92.61  ? 666  VAL A CG2 1 
ATOM   3412 N N   . GLY A 1 545  ? 168.411 144.904 117.250 1.00 95.46  ? 667  GLY A N   1 
ATOM   3413 C CA  . GLY A 1 545  ? 168.052 143.514 117.036 1.00 98.75  ? 667  GLY A CA  1 
ATOM   3414 C C   . GLY A 1 545  ? 169.264 142.608 116.894 1.00 106.01 ? 667  GLY A C   1 
ATOM   3415 O O   . GLY A 1 545  ? 170.411 143.005 117.121 1.00 108.93 ? 667  GLY A O   1 
ATOM   3416 N N   . GLU A 1 546  ? 168.996 141.367 116.502 1.00 104.93 ? 668  GLU A N   1 
ATOM   3417 C CA  . GLU A 1 546  ? 170.039 140.397 116.216 1.00 105.67 ? 668  GLU A CA  1 
ATOM   3418 C C   . GLU A 1 546  ? 170.051 140.071 114.730 1.00 101.80 ? 668  GLU A C   1 
ATOM   3419 O O   . GLU A 1 546  ? 169.162 140.474 113.977 1.00 106.27 ? 668  GLU A O   1 
ATOM   3420 C CB  . GLU A 1 546  ? 169.852 139.111 117.029 1.00 117.53 ? 668  GLU A CB  1 
ATOM   3421 C CG  . GLU A 1 546  ? 169.954 139.305 118.529 1.00 123.90 ? 668  GLU A CG  1 
ATOM   3422 C CD  . GLU A 1 546  ? 169.684 138.028 119.296 1.00 131.84 ? 668  GLU A CD  1 
ATOM   3423 O OE1 . GLU A 1 546  ? 169.403 136.995 118.653 1.00 129.37 ? 668  GLU A OE1 1 
ATOM   3424 O OE2 . GLU A 1 546  ? 169.753 138.059 120.543 1.00 133.97 ? 668  GLU A OE2 1 
ATOM   3425 N N   . SER A 1 547  ? 171.080 139.338 114.318 1.00 98.83  ? 669  SER A N   1 
ATOM   3426 C CA  . SER A 1 547  ? 171.195 138.936 112.923 1.00 96.27  ? 669  SER A CA  1 
ATOM   3427 C C   . SER A 1 547  ? 170.239 137.791 112.604 1.00 97.64  ? 669  SER A C   1 
ATOM   3428 O O   . SER A 1 547  ? 169.812 137.045 113.490 1.00 100.62 ? 669  SER A O   1 
ATOM   3429 C CB  . SER A 1 547  ? 172.636 138.540 112.604 1.00 96.29  ? 669  SER A CB  1 
ATOM   3430 O OG  . SER A 1 547  ? 173.505 139.659 112.682 1.00 96.53  ? 669  SER A OG  1 
ATOM   3431 N N   . PHE A 1 548  ? 169.892 137.682 111.323 1.00 94.60  ? 670  PHE A N   1 
ATOM   3432 C CA  . PHE A 1 548  ? 168.903 136.757 110.781 1.00 97.05  ? 670  PHE A CA  1 
ATOM   3433 C C   . PHE A 1 548  ? 169.224 136.466 109.318 1.00 99.31  ? 670  PHE A C   1 
ATOM   3434 O O   . PHE A 1 548  ? 170.002 137.191 108.695 1.00 96.80  ? 670  PHE A O   1 
ATOM   3435 C CB  . PHE A 1 548  ? 167.452 137.299 111.023 1.00 97.08  ? 670  PHE A CB  1 
ATOM   3436 C CG  . PHE A 1 548  ? 167.141 138.628 110.350 1.00 97.07  ? 670  PHE A CG  1 
ATOM   3437 C CD1 . PHE A 1 548  ? 167.390 139.823 111.044 1.00 91.93  ? 670  PHE A CD1 1 
ATOM   3438 C CD2 . PHE A 1 548  ? 166.592 138.699 109.066 1.00 95.61  ? 670  PHE A CD2 1 
ATOM   3439 C CE1 . PHE A 1 548  ? 167.124 141.057 110.472 1.00 83.56  ? 670  PHE A CE1 1 
ATOM   3440 C CE2 . PHE A 1 548  ? 166.324 139.945 108.479 1.00 87.99  ? 670  PHE A CE2 1 
ATOM   3441 C CZ  . PHE A 1 548  ? 166.590 141.116 109.193 1.00 81.01  ? 670  PHE A CZ  1 
ATOM   3442 N N   . ASP A 1 549  ? 168.668 135.370 108.784 1.00 100.54 ? 671  ASP A N   1 
ATOM   3443 C CA  . ASP A 1 549  ? 169.194 134.819 107.535 1.00 105.07 ? 671  ASP A CA  1 
ATOM   3444 C C   . ASP A 1 549  ? 168.346 135.200 106.328 1.00 101.19 ? 671  ASP A C   1 
ATOM   3445 O O   . ASP A 1 549  ? 168.856 135.257 105.203 1.00 100.60 ? 671  ASP A O   1 
ATOM   3446 C CB  . ASP A 1 549  ? 169.313 133.296 107.649 1.00 114.46 ? 671  ASP A CB  1 
ATOM   3447 C CG  . ASP A 1 549  ? 170.241 132.694 106.599 1.00 121.94 ? 671  ASP A CG  1 
ATOM   3448 O OD1 . ASP A 1 549  ? 171.137 133.414 106.111 1.00 125.58 ? 671  ASP A OD1 1 
ATOM   3449 O OD2 . ASP A 1 549  ? 170.093 131.495 106.278 1.00 120.76 ? 671  ASP A OD2 1 
ATOM   3450 N N   . LEU A 1 550  ? 167.060 135.453 106.524 1.00 98.05  ? 672  LEU A N   1 
ATOM   3451 C CA  . LEU A 1 550  ? 166.180 135.684 105.383 1.00 96.63  ? 672  LEU A CA  1 
ATOM   3452 C C   . LEU A 1 550  ? 166.175 137.160 104.991 1.00 97.63  ? 672  LEU A C   1 
ATOM   3453 O O   . LEU A 1 550  ? 166.272 138.025 105.864 1.00 97.80  ? 672  LEU A O   1 
ATOM   3454 C CB  . LEU A 1 550  ? 164.771 135.181 105.695 1.00 94.25  ? 672  LEU A CB  1 
ATOM   3455 C CG  . LEU A 1 550  ? 164.634 133.669 105.489 1.00 95.80  ? 672  LEU A CG  1 
ATOM   3456 C CD1 . LEU A 1 550  ? 163.271 133.185 105.918 1.00 93.74  ? 672  LEU A CD1 1 
ATOM   3457 C CD2 . LEU A 1 550  ? 164.871 133.308 104.024 1.00 98.58  ? 672  LEU A CD2 1 
ATOM   3458 N N   . PRO A 1 551  ? 166.098 137.485 103.695 1.00 93.70  ? 673  PRO A N   1 
ATOM   3459 C CA  . PRO A 1 551  ? 166.186 138.893 103.287 1.00 88.76  ? 673  PRO A CA  1 
ATOM   3460 C C   . PRO A 1 551  ? 164.900 139.668 103.509 1.00 84.73  ? 673  PRO A C   1 
ATOM   3461 O O   . PRO A 1 551  ? 163.795 139.157 103.315 1.00 89.79  ? 673  PRO A O   1 
ATOM   3462 C CB  . PRO A 1 551  ? 166.543 138.801 101.798 1.00 88.45  ? 673  PRO A CB  1 
ATOM   3463 C CG  . PRO A 1 551  ? 165.982 137.508 101.362 1.00 88.32  ? 673  PRO A CG  1 
ATOM   3464 C CD  . PRO A 1 551  ? 166.152 136.584 102.525 1.00 92.23  ? 673  PRO A CD  1 
ATOM   3465 N N   . VAL A 1 552  ? 165.074 140.922 103.926 1.00 74.01  ? 674  VAL A N   1 
ATOM   3466 C CA  . VAL A 1 552  ? 163.960 141.841 104.101 1.00 68.34  ? 674  VAL A CA  1 
ATOM   3467 C C   . VAL A 1 552  ? 163.462 142.268 102.730 1.00 75.37  ? 674  VAL A C   1 
ATOM   3468 O O   . VAL A 1 552  ? 164.246 142.704 101.880 1.00 86.02  ? 674  VAL A O   1 
ATOM   3469 C CB  . VAL A 1 552  ? 164.400 143.055 104.933 1.00 65.61  ? 674  VAL A CB  1 
ATOM   3470 C CG1 . VAL A 1 552  ? 163.240 143.990 105.211 1.00 64.65  ? 674  VAL A CG1 1 
ATOM   3471 C CG2 . VAL A 1 552  ? 165.030 142.602 106.218 1.00 70.15  ? 674  VAL A CG2 1 
ATOM   3472 N N   . GLU A 1 553  ? 162.163 142.118 102.497 1.00 67.57  ? 675  GLU A N   1 
ATOM   3473 C CA  . GLU A 1 553  ? 161.600 142.576 101.238 1.00 68.20  ? 675  GLU A CA  1 
ATOM   3474 C C   . GLU A 1 553  ? 160.910 143.923 101.371 1.00 66.62  ? 675  GLU A C   1 
ATOM   3475 O O   . GLU A 1 553  ? 160.733 144.616 100.363 1.00 71.75  ? 675  GLU A O   1 
ATOM   3476 C CB  . GLU A 1 553  ? 160.632 141.536 100.678 1.00 67.87  ? 675  GLU A CB  1 
ATOM   3477 C CG  . GLU A 1 553  ? 161.319 140.253 100.253 1.00 80.82  ? 675  GLU A CG  1 
ATOM   3478 C CD  . GLU A 1 553  ? 160.353 139.218 99.717  1.00 100.25 ? 675  GLU A CD  1 
ATOM   3479 O OE1 . GLU A 1 553  ? 159.129 139.449 99.790  1.00 94.83  ? 675  GLU A OE1 1 
ATOM   3480 O OE2 . GLU A 1 553  ? 160.820 138.174 99.219  1.00 107.16 ? 675  GLU A OE2 1 
ATOM   3481 N N   . GLN A 1 554  ? 160.531 144.312 102.589 1.00 59.64  ? 676  GLN A N   1 
ATOM   3482 C CA  . GLN A 1 554  ? 159.961 145.626 102.861 1.00 58.25  ? 676  GLN A CA  1 
ATOM   3483 C C   . GLN A 1 554  ? 160.226 145.980 104.315 1.00 57.66  ? 676  GLN A C   1 
ATOM   3484 O O   . GLN A 1 554  ? 160.021 145.147 105.199 1.00 56.18  ? 676  GLN A O   1 
ATOM   3485 C CB  . GLN A 1 554  ? 158.456 145.653 102.578 1.00 56.33  ? 676  GLN A CB  1 
ATOM   3486 C CG  . GLN A 1 554  ? 157.806 147.014 102.695 1.00 54.16  ? 676  GLN A CG  1 
ATOM   3487 C CD  . GLN A 1 554  ? 156.335 146.961 102.398 1.00 55.55  ? 676  GLN A CD  1 
ATOM   3488 O OE1 . GLN A 1 554  ? 155.839 145.968 101.876 1.00 60.12  ? 676  GLN A OE1 1 
ATOM   3489 N NE2 . GLN A 1 554  ? 155.621 148.023 102.742 1.00 59.63  ? 676  GLN A NE2 1 
ATOM   3490 N N   . LEU A 1 555  ? 160.684 147.205 104.557 1.00 60.82  ? 677  LEU A N   1 
ATOM   3491 C CA  . LEU A 1 555  ? 160.960 147.701 105.898 1.00 57.69  ? 677  LEU A CA  1 
ATOM   3492 C C   . LEU A 1 555  ? 160.082 148.912 106.173 1.00 63.15  ? 677  LEU A C   1 
ATOM   3493 O O   . LEU A 1 555  ? 160.096 149.875 105.402 1.00 70.06  ? 677  LEU A O   1 
ATOM   3494 C CB  . LEU A 1 555  ? 162.432 148.086 106.034 1.00 60.72  ? 677  LEU A CB  1 
ATOM   3495 C CG  . LEU A 1 555  ? 162.937 148.464 107.422 1.00 56.57  ? 677  LEU A CG  1 
ATOM   3496 C CD1 . LEU A 1 555  ? 162.883 147.260 108.312 1.00 59.84  ? 677  LEU A CD1 1 
ATOM   3497 C CD2 . LEU A 1 555  ? 164.339 149.016 107.359 1.00 60.38  ? 677  LEU A CD2 1 
ATOM   3498 N N   . GLU A 1 556  ? 159.299 148.859 107.255 1.00 55.84  ? 678  GLU A N   1 
ATOM   3499 C CA  . GLU A 1 556  ? 158.497 149.998 107.692 1.00 57.13  ? 678  GLU A CA  1 
ATOM   3500 C C   . GLU A 1 556  ? 158.720 150.255 109.174 1.00 54.91  ? 678  GLU A C   1 
ATOM   3501 O O   . GLU A 1 556  ? 158.817 149.313 109.962 1.00 55.61  ? 678  GLU A O   1 
ATOM   3502 C CB  . GLU A 1 556  ? 156.989 149.799 107.438 1.00 60.18  ? 678  GLU A CB  1 
ATOM   3503 C CG  . GLU A 1 556  ? 156.558 149.352 106.036 1.00 62.12  ? 678  GLU A CG  1 
ATOM   3504 C CD  . GLU A 1 556  ? 156.720 150.423 104.964 1.00 74.33  ? 678  GLU A CD  1 
ATOM   3505 O OE1 . GLU A 1 556  ? 156.753 150.055 103.771 1.00 71.62  ? 678  GLU A OE1 1 
ATOM   3506 O OE2 . GLU A 1 556  ? 156.774 151.627 105.294 1.00 77.70  ? 678  GLU A OE2 1 
ATOM   3507 N N   . VAL A 1 557  ? 158.785 151.529 109.547 1.00 55.91  ? 679  VAL A N   1 
ATOM   3508 C CA  . VAL A 1 557  ? 158.919 151.959 110.934 1.00 55.34  ? 679  VAL A CA  1 
ATOM   3509 C C   . VAL A 1 557  ? 157.607 152.598 111.361 1.00 53.56  ? 679  VAL A C   1 
ATOM   3510 O O   . VAL A 1 557  ? 157.074 153.457 110.653 1.00 61.54  ? 679  VAL A O   1 
ATOM   3511 C CB  . VAL A 1 557  ? 160.094 152.940 111.107 1.00 59.49  ? 679  VAL A CB  1 
ATOM   3512 C CG1 . VAL A 1 557  ? 160.283 153.333 112.554 1.00 55.75  ? 679  VAL A CG1 1 
ATOM   3513 C CG2 . VAL A 1 557  ? 161.368 152.315 110.619 1.00 58.98  ? 679  VAL A CG2 1 
ATOM   3514 N N   . ASP A 1 558  ? 157.066 152.152 112.492 1.00 52.37  ? 680  ASP A N   1 
ATOM   3515 C CA  . ASP A 1 558  ? 155.987 152.851 113.182 1.00 51.13  ? 680  ASP A CA  1 
ATOM   3516 C C   . ASP A 1 558  ? 156.638 153.725 114.247 1.00 62.27  ? 680  ASP A C   1 
ATOM   3517 O O   . ASP A 1 558  ? 156.952 153.254 115.341 1.00 63.77  ? 680  ASP A O   1 
ATOM   3518 C CB  . ASP A 1 558  ? 155.004 151.866 113.800 1.00 54.46  ? 680  ASP A CB  1 
ATOM   3519 C CG  . ASP A 1 558  ? 153.684 152.501 114.158 1.00 60.70  ? 680  ASP A CG  1 
ATOM   3520 O OD1 . ASP A 1 558  ? 153.490 153.694 113.862 1.00 60.30  ? 680  ASP A OD1 1 
ATOM   3521 O OD2 . ASP A 1 558  ? 152.834 151.804 114.742 1.00 66.58  ? 680  ASP A OD2 1 
ATOM   3522 N N   . ALA A 1 559  ? 156.825 155.004 113.925 1.00 67.88  ? 681  ALA A N   1 
ATOM   3523 C CA  . ALA A 1 559  ? 157.511 155.915 114.831 1.00 64.86  ? 681  ALA A CA  1 
ATOM   3524 C C   . ALA A 1 559  ? 156.641 156.333 116.007 1.00 69.01  ? 681  ALA A C   1 
ATOM   3525 O O   . ALA A 1 559  ? 157.168 156.563 117.100 1.00 72.78  ? 681  ALA A O   1 
ATOM   3526 C CB  . ALA A 1 559  ? 157.979 157.152 114.072 1.00 63.53  ? 681  ALA A CB  1 
ATOM   3527 N N   . LEU A 1 560  ? 155.322 156.414 115.798 1.00 66.26  ? 682  LEU A N   1 
ATOM   3528 C CA  . LEU A 1 560  ? 154.388 156.881 116.819 1.00 64.06  ? 682  LEU A CA  1 
ATOM   3529 C C   . LEU A 1 560  ? 154.211 155.858 117.934 1.00 67.38  ? 682  LEU A C   1 
ATOM   3530 O O   . LEU A 1 560  ? 154.218 156.210 119.119 1.00 76.10  ? 682  LEU A O   1 
ATOM   3531 C CB  . LEU A 1 560  ? 153.042 157.210 116.172 1.00 58.97  ? 682  LEU A CB  1 
ATOM   3532 C CG  . LEU A 1 560  ? 151.900 157.636 117.094 1.00 59.41  ? 682  LEU A CG  1 
ATOM   3533 C CD1 . LEU A 1 560  ? 152.168 159.013 117.667 1.00 66.62  ? 682  LEU A CD1 1 
ATOM   3534 C CD2 . LEU A 1 560  ? 150.572 157.605 116.364 1.00 54.94  ? 682  LEU A CD2 1 
ATOM   3535 N N   . ASN A 1 561  ? 154.068 154.588 117.578 1.00 62.39  ? 683  ASN A N   1 
ATOM   3536 C CA  . ASN A 1 561  ? 153.911 153.534 118.565 1.00 56.57  ? 683  ASN A CA  1 
ATOM   3537 C C   . ASN A 1 561  ? 155.225 152.861 118.918 1.00 58.26  ? 683  ASN A C   1 
ATOM   3538 O O   . ASN A 1 561  ? 155.231 151.955 119.757 1.00 62.86  ? 683  ASN A O   1 
ATOM   3539 C CB  . ASN A 1 561  ? 152.905 152.507 118.062 1.00 57.25  ? 683  ASN A CB  1 
ATOM   3540 C CG  . ASN A 1 561  ? 151.591 153.139 117.697 1.00 64.82  ? 683  ASN A CG  1 
ATOM   3541 O OD1 . ASN A 1 561  ? 151.027 153.895 118.480 1.00 67.82  ? 683  ASN A OD1 1 
ATOM   3542 N ND2 . ASN A 1 561  ? 151.098 152.845 116.504 1.00 65.01  ? 683  ASN A ND2 1 
ATOM   3543 N N   . GLY A 1 562  ? 156.327 153.305 118.327 1.00 57.50  ? 684  GLY A N   1 
ATOM   3544 C CA  . GLY A 1 562  ? 157.648 152.781 118.620 1.00 59.96  ? 684  GLY A CA  1 
ATOM   3545 C C   . GLY A 1 562  ? 157.904 151.368 118.150 1.00 57.18  ? 684  GLY A C   1 
ATOM   3546 O O   . GLY A 1 562  ? 158.528 150.586 118.874 1.00 61.59  ? 684  GLY A O   1 
ATOM   3547 N N   . TRP A 1 563  ? 157.431 151.018 116.960 1.00 56.21  ? 685  TRP A N   1 
ATOM   3548 C CA  . TRP A 1 563  ? 157.650 149.697 116.401 1.00 51.86  ? 685  TRP A CA  1 
ATOM   3549 C C   . TRP A 1 563  ? 158.388 149.804 115.077 1.00 53.77  ? 685  TRP A C   1 
ATOM   3550 O O   . TRP A 1 563  ? 158.450 150.865 114.456 1.00 61.97  ? 685  TRP A O   1 
ATOM   3551 C CB  . TRP A 1 563  ? 156.337 148.937 116.174 1.00 50.87  ? 685  TRP A CB  1 
ATOM   3552 C CG  . TRP A 1 563  ? 155.537 148.636 117.400 1.00 51.31  ? 685  TRP A CG  1 
ATOM   3553 C CD1 . TRP A 1 563  ? 154.313 149.142 117.710 1.00 53.41  ? 685  TRP A CD1 1 
ATOM   3554 C CD2 . TRP A 1 563  ? 155.882 147.742 118.466 1.00 51.89  ? 685  TRP A CD2 1 
ATOM   3555 N NE1 . TRP A 1 563  ? 153.877 148.633 118.903 1.00 54.43  ? 685  TRP A NE1 1 
ATOM   3556 C CE2 . TRP A 1 563  ? 154.821 147.771 119.391 1.00 54.05  ? 685  TRP A CE2 1 
ATOM   3557 C CE3 . TRP A 1 563  ? 156.989 146.927 118.733 1.00 55.32  ? 685  TRP A CE3 1 
ATOM   3558 C CZ2 . TRP A 1 563  ? 154.831 147.014 120.562 1.00 57.86  ? 685  TRP A CZ2 1 
ATOM   3559 C CZ3 . TRP A 1 563  ? 156.999 146.175 119.898 1.00 58.57  ? 685  TRP A CZ3 1 
ATOM   3560 C CH2 . TRP A 1 563  ? 155.925 146.223 120.797 1.00 57.92  ? 685  TRP A CH2 1 
ATOM   3561 N N   . ILE A 1 564  ? 158.965 148.688 114.656 1.00 52.46  ? 686  ILE A N   1 
ATOM   3562 C CA  . ILE A 1 564  ? 159.473 148.538 113.302 1.00 52.98  ? 686  ILE A CA  1 
ATOM   3563 C C   . ILE A 1 564  ? 159.041 147.174 112.773 1.00 56.38  ? 686  ILE A C   1 
ATOM   3564 O O   . ILE A 1 564  ? 159.226 146.148 113.436 1.00 62.38  ? 686  ILE A O   1 
ATOM   3565 C CB  . ILE A 1 564  ? 161.002 148.766 113.228 1.00 52.65  ? 686  ILE A CB  1 
ATOM   3566 C CG1 . ILE A 1 564  ? 161.550 148.536 111.821 1.00 56.32  ? 686  ILE A CG1 1 
ATOM   3567 C CG2 . ILE A 1 564  ? 161.785 148.081 114.339 1.00 55.87  ? 686  ILE A CG2 1 
ATOM   3568 C CD1 . ILE A 1 564  ? 162.957 149.004 111.671 1.00 59.88  ? 686  ILE A CD1 1 
ATOM   3569 N N   . PHE A 1 565  ? 158.394 147.177 111.613 1.00 52.74  ? 687  PHE A N   1 
ATOM   3570 C CA  . PHE A 1 565  ? 157.858 145.974 110.998 1.00 51.62  ? 687  PHE A CA  1 
ATOM   3571 C C   . PHE A 1 565  ? 158.656 145.660 109.748 1.00 54.15  ? 687  PHE A C   1 
ATOM   3572 O O   . PHE A 1 565  ? 158.889 146.543 108.918 1.00 54.84  ? 687  PHE A O   1 
ATOM   3573 C CB  . PHE A 1 565  ? 156.382 146.133 110.624 1.00 52.58  ? 687  PHE A CB  1 
ATOM   3574 C CG  . PHE A 1 565  ? 155.507 146.614 111.740 1.00 47.86  ? 687  PHE A CG  1 
ATOM   3575 C CD1 . PHE A 1 565  ? 155.001 145.710 112.675 1.00 44.52  ? 687  PHE A CD1 1 
ATOM   3576 C CD2 . PHE A 1 565  ? 155.151 147.960 111.832 1.00 50.14  ? 687  PHE A CD2 1 
ATOM   3577 C CE1 . PHE A 1 565  ? 154.172 146.147 113.703 1.00 44.99  ? 687  PHE A CE1 1 
ATOM   3578 C CE2 . PHE A 1 565  ? 154.326 148.403 112.858 1.00 50.88  ? 687  PHE A CE2 1 
ATOM   3579 C CZ  . PHE A 1 565  ? 153.841 147.493 113.792 1.00 51.44  ? 687  PHE A CZ  1 
ATOM   3580 N N   . TRP A 1 566  ? 159.063 144.407 109.603 1.00 58.35  ? 688  TRP A N   1 
ATOM   3581 C CA  . TRP A 1 566  ? 159.712 143.983 108.378 1.00 60.78  ? 688  TRP A CA  1 
ATOM   3582 C C   . TRP A 1 566  ? 159.117 142.668 107.923 1.00 60.50  ? 688  TRP A C   1 
ATOM   3583 O O   . TRP A 1 566  ? 158.456 141.955 108.680 1.00 63.00  ? 688  TRP A O   1 
ATOM   3584 C CB  . TRP A 1 566  ? 161.235 143.884 108.529 1.00 66.29  ? 688  TRP A CB  1 
ATOM   3585 C CG  . TRP A 1 566  ? 161.782 142.698 109.246 1.00 62.57  ? 688  TRP A CG  1 
ATOM   3586 C CD1 . TRP A 1 566  ? 162.243 141.542 108.690 1.00 66.83  ? 688  TRP A CD1 1 
ATOM   3587 C CD2 . TRP A 1 566  ? 161.997 142.581 110.653 1.00 63.65  ? 688  TRP A CD2 1 
ATOM   3588 N NE1 . TRP A 1 566  ? 162.702 140.698 109.668 1.00 74.55  ? 688  TRP A NE1 1 
ATOM   3589 C CE2 . TRP A 1 566  ? 162.565 141.312 110.882 1.00 71.74  ? 688  TRP A CE2 1 
ATOM   3590 C CE3 . TRP A 1 566  ? 161.751 143.420 111.743 1.00 64.56  ? 688  TRP A CE3 1 
ATOM   3591 C CZ2 . TRP A 1 566  ? 162.900 140.867 112.160 1.00 75.80  ? 688  TRP A CZ2 1 
ATOM   3592 C CZ3 . TRP A 1 566  ? 162.070 142.975 113.009 1.00 70.70  ? 688  TRP A CZ3 1 
ATOM   3593 C CH2 . TRP A 1 566  ? 162.635 141.707 113.209 1.00 73.00  ? 688  TRP A CH2 1 
ATOM   3594 N N   . ARG A 1 567  ? 159.357 142.370 106.656 1.00 60.99  ? 689  ARG A N   1 
ATOM   3595 C CA  . ARG A 1 567  ? 158.764 141.230 105.987 1.00 59.52  ? 689  ARG A CA  1 
ATOM   3596 C C   . ARG A 1 567  ? 159.860 140.486 105.250 1.00 68.48  ? 689  ARG A C   1 
ATOM   3597 O O   . ARG A 1 567  ? 160.625 141.086 104.490 1.00 72.29  ? 689  ARG A O   1 
ATOM   3598 C CB  . ARG A 1 567  ? 157.665 141.692 105.034 1.00 58.28  ? 689  ARG A CB  1 
ATOM   3599 C CG  . ARG A 1 567  ? 157.343 140.745 103.920 1.00 62.83  ? 689  ARG A CG  1 
ATOM   3600 C CD  . ARG A 1 567  ? 156.286 141.333 103.074 1.00 60.45  ? 689  ARG A CD  1 
ATOM   3601 N NE  . ARG A 1 567  ? 156.768 142.414 102.223 1.00 58.71  ? 689  ARG A NE  1 
ATOM   3602 C CZ  . ARG A 1 567  ? 156.961 142.310 100.916 1.00 61.96  ? 689  ARG A CZ  1 
ATOM   3603 N NH1 . ARG A 1 567  ? 156.753 141.174 100.275 1.00 71.21  ? 689  ARG A NH1 1 
ATOM   3604 N NH2 . ARG A 1 567  ? 157.345 143.381 100.230 1.00 56.12  ? 689  ARG A NH2 1 
ATOM   3605 N N   . ASN A 1 568  ? 159.954 139.197 105.504 1.00 74.43  ? 690  ASN A N   1 
ATOM   3606 C CA  . ASN A 1 568  ? 160.869 138.333 104.793 1.00 75.87  ? 690  ASN A CA  1 
ATOM   3607 C C   . ASN A 1 568  ? 160.108 137.368 103.877 1.00 79.97  ? 690  ASN A C   1 
ATOM   3608 O O   . ASN A 1 568  ? 158.911 137.538 103.616 1.00 79.56  ? 690  ASN A O   1 
ATOM   3609 C CB  . ASN A 1 568  ? 161.862 137.688 105.786 1.00 76.57  ? 690  ASN A CB  1 
ATOM   3610 C CG  . ASN A 1 568  ? 161.221 136.776 106.852 1.00 85.32  ? 690  ASN A CG  1 
ATOM   3611 O OD1 . ASN A 1 568  ? 160.031 136.473 106.859 1.00 86.83  ? 690  ASN A OD1 1 
ATOM   3612 N ND2 . ASN A 1 568  ? 162.059 136.335 107.780 1.00 89.17  ? 690  ASN A ND2 1 
ATOM   3613 N N   . GLU A 1 569  ? 160.839 136.379 103.370 1.00 87.21  ? 691  GLU A N   1 
ATOM   3614 C CA  . GLU A 1 569  ? 160.427 135.394 102.377 1.00 95.50  ? 691  GLU A CA  1 
ATOM   3615 C C   . GLU A 1 569  ? 159.279 134.496 102.853 1.00 93.46  ? 691  GLU A C   1 
ATOM   3616 O O   . GLU A 1 569  ? 158.499 134.020 102.020 1.00 94.33  ? 691  GLU A O   1 
ATOM   3617 C CB  . GLU A 1 569  ? 161.685 134.578 102.020 1.00 100.33 ? 691  GLU A CB  1 
ATOM   3618 C CG  . GLU A 1 569  ? 161.634 133.501 100.936 1.00 108.24 ? 691  GLU A CG  1 
ATOM   3619 C CD  . GLU A 1 569  ? 161.411 134.059 99.534  1.00 118.38 ? 691  GLU A CD  1 
ATOM   3620 O OE1 . GLU A 1 569  ? 161.772 135.226 99.282  1.00 119.80 ? 691  GLU A OE1 1 
ATOM   3621 O OE2 . GLU A 1 569  ? 160.939 133.303 98.662  1.00 120.30 ? 691  GLU A OE2 1 
ATOM   3622 N N   . GLU A 1 570  ? 159.136 134.286 104.167 1.00 88.49  ? 692  GLU A N   1 
ATOM   3623 C CA  . GLU A 1 570  ? 158.192 133.328 104.728 1.00 89.78  ? 692  GLU A CA  1 
ATOM   3624 C C   . GLU A 1 570  ? 157.246 133.885 105.785 1.00 87.10  ? 692  GLU A C   1 
ATOM   3625 O O   . GLU A 1 570  ? 156.341 133.157 106.209 1.00 93.49  ? 692  GLU A O   1 
ATOM   3626 C CB  . GLU A 1 570  ? 158.964 132.153 105.349 1.00 96.19  ? 692  GLU A CB  1 
ATOM   3627 C CG  . GLU A 1 570  ? 159.608 132.486 106.691 1.00 97.81  ? 692  GLU A CG  1 
ATOM   3628 C CD  . GLU A 1 570  ? 160.369 131.324 107.295 1.00 111.78 ? 692  GLU A CD  1 
ATOM   3629 O OE1 . GLU A 1 570  ? 160.455 130.260 106.646 1.00 117.07 ? 692  GLU A OE1 1 
ATOM   3630 O OE2 . GLU A 1 570  ? 160.889 131.478 108.419 1.00 116.35 ? 692  GLU A OE2 1 
ATOM   3631 N N   . SER A 1 571  ? 157.426 135.130 106.227 1.00 80.10  ? 693  SER A N   1 
ATOM   3632 C CA  . SER A 1 571  ? 156.806 135.594 107.463 1.00 76.85  ? 693  SER A CA  1 
ATOM   3633 C C   . SER A 1 571  ? 156.780 137.118 107.509 1.00 74.17  ? 693  SER A C   1 
ATOM   3634 O O   . SER A 1 571  ? 157.224 137.798 106.583 1.00 76.75  ? 693  SER A O   1 
ATOM   3635 C CB  . SER A 1 571  ? 157.553 135.033 108.678 1.00 81.58  ? 693  SER A CB  1 
ATOM   3636 O OG  . SER A 1 571  ? 158.692 135.810 108.960 1.00 80.55  ? 693  SER A OG  1 
ATOM   3637 N N   . LEU A 1 572  ? 156.239 137.646 108.609 1.00 69.86  ? 694  LEU A N   1 
ATOM   3638 C CA  . LEU A 1 572  ? 156.200 139.077 108.894 1.00 64.06  ? 694  LEU A CA  1 
ATOM   3639 C C   . LEU A 1 572  ? 156.472 139.269 110.380 1.00 65.59  ? 694  LEU A C   1 
ATOM   3640 O O   . LEU A 1 572  ? 155.941 138.523 111.206 1.00 74.77  ? 694  LEU A O   1 
ATOM   3641 C CB  . LEU A 1 572  ? 154.848 139.683 108.496 1.00 62.53  ? 694  LEU A CB  1 
ATOM   3642 C CG  . LEU A 1 572  ? 154.668 141.197 108.345 1.00 67.74  ? 694  LEU A CG  1 
ATOM   3643 C CD1 . LEU A 1 572  ? 153.738 141.465 107.184 1.00 61.73  ? 694  LEU A CD1 1 
ATOM   3644 C CD2 . LEU A 1 572  ? 154.096 141.841 109.594 1.00 63.82  ? 694  LEU A CD2 1 
ATOM   3645 N N   . TRP A 1 573  ? 157.277 140.271 110.721 1.00 62.87  ? 695  TRP A N   1 
ATOM   3646 C CA  . TRP A 1 573  ? 157.828 140.394 112.066 1.00 61.66  ? 695  TRP A CA  1 
ATOM   3647 C C   . TRP A 1 573  ? 157.504 141.742 112.704 1.00 61.91  ? 695  TRP A C   1 
ATOM   3648 O O   . TRP A 1 573  ? 156.824 142.589 112.124 1.00 68.70  ? 695  TRP A O   1 
ATOM   3649 C CB  . TRP A 1 573  ? 159.337 140.204 112.037 1.00 67.90  ? 695  TRP A CB  1 
ATOM   3650 C CG  . TRP A 1 573  ? 159.779 138.817 111.845 1.00 76.31  ? 695  TRP A CG  1 
ATOM   3651 C CD1 . TRP A 1 573  ? 159.910 138.166 110.668 1.00 76.02  ? 695  TRP A CD1 1 
ATOM   3652 C CD2 . TRP A 1 573  ? 160.187 137.901 112.865 1.00 78.93  ? 695  TRP A CD2 1 
ATOM   3653 N NE1 . TRP A 1 573  ? 160.353 136.884 110.879 1.00 76.85  ? 695  TRP A NE1 1 
ATOM   3654 C CE2 . TRP A 1 573  ? 160.536 136.698 112.224 1.00 78.61  ? 695  TRP A CE2 1 
ATOM   3655 C CE3 . TRP A 1 573  ? 160.286 137.982 114.259 1.00 76.29  ? 695  TRP A CE3 1 
ATOM   3656 C CZ2 . TRP A 1 573  ? 160.977 135.579 112.928 1.00 79.41  ? 695  TRP A CZ2 1 
ATOM   3657 C CZ3 . TRP A 1 573  ? 160.723 136.870 114.960 1.00 77.55  ? 695  TRP A CZ3 1 
ATOM   3658 C CH2 . TRP A 1 573  ? 161.062 135.683 114.292 1.00 80.86  ? 695  TRP A CH2 1 
ATOM   3659 N N   . ARG A 1 574  ? 158.035 141.929 113.912 1.00 59.47  ? 696  ARG A N   1 
ATOM   3660 C CA  . ARG A 1 574  ? 157.848 143.141 114.698 1.00 54.63  ? 696  ARG A CA  1 
ATOM   3661 C C   . ARG A 1 574  ? 158.974 143.265 115.711 1.00 60.55  ? 696  ARG A C   1 
ATOM   3662 O O   . ARG A 1 574  ? 159.179 142.357 116.519 1.00 72.39  ? 696  ARG A O   1 
ATOM   3663 C CB  . ARG A 1 574  ? 156.509 143.127 115.432 1.00 61.59  ? 696  ARG A CB  1 
ATOM   3664 C CG  . ARG A 1 574  ? 156.225 144.407 116.168 1.00 59.85  ? 696  ARG A CG  1 
ATOM   3665 C CD  . ARG A 1 574  ? 155.013 144.283 117.062 1.00 62.34  ? 696  ARG A CD  1 
ATOM   3666 N NE  . ARG A 1 574  ? 155.265 143.430 118.215 1.00 61.45  ? 696  ARG A NE  1 
ATOM   3667 C CZ  . ARG A 1 574  ? 154.445 143.315 119.248 1.00 64.18  ? 696  ARG A CZ  1 
ATOM   3668 N NH1 . ARG A 1 574  ? 153.302 143.977 119.299 1.00 58.30  ? 696  ARG A NH1 1 
ATOM   3669 N NH2 . ARG A 1 574  ? 154.781 142.519 120.257 1.00 71.21  ? 696  ARG A NH2 1 
ATOM   3670 N N   . GLN A 1 575  ? 159.689 144.382 115.671 1.00 60.21  ? 697  GLN A N   1 
ATOM   3671 C CA  . GLN A 1 575  ? 160.624 144.768 116.715 1.00 58.46  ? 697  GLN A CA  1 
ATOM   3672 C C   . GLN A 1 575  ? 160.224 146.143 117.213 1.00 63.50  ? 697  GLN A C   1 
ATOM   3673 O O   . GLN A 1 575  ? 159.467 146.855 116.554 1.00 71.07  ? 697  GLN A O   1 
ATOM   3674 C CB  . GLN A 1 575  ? 162.067 144.825 116.210 1.00 60.73  ? 697  GLN A CB  1 
ATOM   3675 C CG  . GLN A 1 575  ? 162.914 143.632 116.514 1.00 70.90  ? 697  GLN A CG  1 
ATOM   3676 C CD  . GLN A 1 575  ? 164.207 143.649 115.734 1.00 71.40  ? 697  GLN A CD  1 
ATOM   3677 O OE1 . GLN A 1 575  ? 164.522 144.627 115.062 1.00 71.38  ? 697  GLN A OE1 1 
ATOM   3678 N NE2 . GLN A 1 575  ? 164.957 142.558 115.805 1.00 79.49  ? 697  GLN A NE2 1 
ATOM   3679 N N   . ASP A 1 576  ? 160.737 146.528 118.377 1.00 61.82  ? 698  ASP A N   1 
ATOM   3680 C CA  . ASP A 1 576  ? 160.659 147.930 118.744 1.00 63.27  ? 698  ASP A CA  1 
ATOM   3681 C C   . ASP A 1 576  ? 161.921 148.639 118.260 1.00 74.49  ? 698  ASP A C   1 
ATOM   3682 O O   . ASP A 1 576  ? 162.772 148.054 117.588 1.00 80.99  ? 698  ASP A O   1 
ATOM   3683 C CB  . ASP A 1 576  ? 160.444 148.116 120.244 1.00 66.10  ? 698  ASP A CB  1 
ATOM   3684 C CG  . ASP A 1 576  ? 161.434 147.351 121.081 1.00 84.09  ? 698  ASP A CG  1 
ATOM   3685 O OD1 . ASP A 1 576  ? 162.068 146.415 120.558 1.00 90.49  ? 698  ASP A OD1 1 
ATOM   3686 O OD2 . ASP A 1 576  ? 161.586 147.696 122.270 1.00 91.14  ? 698  ASP A OD2 1 
ATOM   3687 N N   . LEU A 1 577  ? 162.053 149.916 118.614 1.00 75.94  ? 699  LEU A N   1 
ATOM   3688 C CA  . LEU A 1 577  ? 163.137 150.735 118.086 1.00 77.92  ? 699  LEU A CA  1 
ATOM   3689 C C   . LEU A 1 577  ? 164.477 150.472 118.761 1.00 91.29  ? 699  LEU A C   1 
ATOM   3690 O O   . LEU A 1 577  ? 165.509 150.897 118.232 1.00 96.11  ? 699  LEU A O   1 
ATOM   3691 C CB  . LEU A 1 577  ? 162.777 152.216 118.214 1.00 71.58  ? 699  LEU A CB  1 
ATOM   3692 C CG  . LEU A 1 577  ? 161.549 152.655 117.416 1.00 65.78  ? 699  LEU A CG  1 
ATOM   3693 C CD1 . LEU A 1 577  ? 161.235 154.120 117.662 1.00 71.73  ? 699  LEU A CD1 1 
ATOM   3694 C CD2 . LEU A 1 577  ? 161.723 152.376 115.939 1.00 64.74  ? 699  LEU A CD2 1 
ATOM   3695 N N   . HIS A 1 578  ? 164.490 149.788 119.904 1.00 90.57  ? 700  HIS A N   1 
ATOM   3696 C CA  . HIS A 1 578  ? 165.723 149.368 120.548 1.00 90.33  ? 700  HIS A CA  1 
ATOM   3697 C C   . HIS A 1 578  ? 165.901 147.857 120.552 1.00 91.36  ? 700  HIS A C   1 
ATOM   3698 O O   . HIS A 1 578  ? 166.828 147.358 121.198 1.00 101.50 ? 700  HIS A O   1 
ATOM   3699 C CB  . HIS A 1 578  ? 165.781 149.912 121.978 1.00 93.63  ? 700  HIS A CB  1 
ATOM   3700 C CG  . HIS A 1 578  ? 165.976 151.394 122.044 1.00 101.55 ? 700  HIS A CG  1 
ATOM   3701 N ND1 . HIS A 1 578  ? 165.841 152.114 123.211 1.00 110.72 ? 700  HIS A ND1 1 
ATOM   3702 C CD2 . HIS A 1 578  ? 166.293 152.293 121.084 1.00 100.57 ? 700  HIS A CD2 1 
ATOM   3703 C CE1 . HIS A 1 578  ? 166.070 153.392 122.969 1.00 114.01 ? 700  HIS A CE1 1 
ATOM   3704 N NE2 . HIS A 1 578  ? 166.345 153.528 121.683 1.00 108.91 ? 700  HIS A NE2 1 
ATOM   3705 N N   . GLY A 1 579  ? 165.044 147.118 119.848 1.00 85.35  ? 701  GLY A N   1 
ATOM   3706 C CA  . GLY A 1 579  ? 165.231 145.699 119.634 1.00 85.29  ? 701  GLY A CA  1 
ATOM   3707 C C   . GLY A 1 579  ? 164.868 144.814 120.800 1.00 84.17  ? 701  GLY A C   1 
ATOM   3708 O O   . GLY A 1 579  ? 165.292 143.653 120.826 1.00 86.64  ? 701  GLY A O   1 
ATOM   3709 N N   . ARG A 1 580  ? 164.091 145.317 121.760 1.00 83.08  ? 702  ARG A N   1 
ATOM   3710 C CA  . ARG A 1 580  ? 163.856 144.576 122.995 1.00 87.62  ? 702  ARG A CA  1 
ATOM   3711 C C   . ARG A 1 580  ? 162.785 143.509 122.809 1.00 88.82  ? 702  ARG A C   1 
ATOM   3712 O O   . ARG A 1 580  ? 162.981 142.346 123.179 1.00 94.31  ? 702  ARG A O   1 
ATOM   3713 C CB  . ARG A 1 580  ? 163.464 145.548 124.106 1.00 86.52  ? 702  ARG A CB  1 
ATOM   3714 C CG  . ARG A 1 580  ? 164.469 146.665 124.307 1.00 91.94  ? 702  ARG A CG  1 
ATOM   3715 C CD  . ARG A 1 580  ? 163.900 147.777 125.164 1.00 99.96  ? 702  ARG A CD  1 
ATOM   3716 N NE  . ARG A 1 580  ? 164.856 148.862 125.342 1.00 107.91 ? 702  ARG A NE  1 
ATOM   3717 C CZ  . ARG A 1 580  ? 164.598 149.987 125.994 1.00 110.73 ? 702  ARG A CZ  1 
ATOM   3718 N NH1 . ARG A 1 580  ? 163.411 150.217 126.530 1.00 113.78 ? 702  ARG A NH1 1 
ATOM   3719 N NH2 . ARG A 1 580  ? 165.554 150.904 126.110 1.00 107.72 ? 702  ARG A NH2 1 
ATOM   3720 N N   . MET A 1 581  ? 161.646 143.884 122.237 1.00 81.82  ? 703  MET A N   1 
ATOM   3721 C CA  . MET A 1 581  ? 160.520 142.978 122.056 1.00 77.07  ? 703  MET A CA  1 
ATOM   3722 C C   . MET A 1 581  ? 160.470 142.539 120.603 1.00 75.91  ? 703  MET A C   1 
ATOM   3723 O O   . MET A 1 581  ? 160.037 143.305 119.737 1.00 78.79  ? 703  MET A O   1 
ATOM   3724 C CB  . MET A 1 581  ? 159.207 143.649 122.455 1.00 78.94  ? 703  MET A CB  1 
ATOM   3725 C CG  . MET A 1 581  ? 158.930 143.639 123.944 1.00 88.95  ? 703  MET A CG  1 
ATOM   3726 S SD  . MET A 1 581  ? 157.561 144.721 124.391 1.00 104.20 ? 703  MET A SD  1 
ATOM   3727 C CE  . MET A 1 581  ? 158.391 146.307 124.435 1.00 84.28  ? 703  MET A CE  1 
ATOM   3728 N N   . ILE A 1 582  ? 160.900 141.310 120.337 1.00 72.51  ? 704  ILE A N   1 
ATOM   3729 C CA  . ILE A 1 582  ? 160.871 140.737 118.998 1.00 64.75  ? 704  ILE A CA  1 
ATOM   3730 C C   . ILE A 1 582  ? 159.696 139.777 118.932 1.00 68.26  ? 704  ILE A C   1 
ATOM   3731 O O   . ILE A 1 582  ? 159.611 138.837 119.731 1.00 77.96  ? 704  ILE A O   1 
ATOM   3732 C CB  . ILE A 1 582  ? 162.183 140.011 118.651 1.00 63.50  ? 704  ILE A CB  1 
ATOM   3733 C CG1 . ILE A 1 582  ? 163.383 140.880 119.020 1.00 70.46  ? 704  ILE A CG1 1 
ATOM   3734 C CG2 . ILE A 1 582  ? 162.215 139.671 117.173 1.00 57.68  ? 704  ILE A CG2 1 
ATOM   3735 C CD1 . ILE A 1 582  ? 164.713 140.177 118.884 1.00 74.11  ? 704  ILE A CD1 1 
ATOM   3736 N N   . HIS A 1 583  ? 158.790 140.016 117.990 1.00 67.19  ? 705  HIS A N   1 
ATOM   3737 C CA  . HIS A 1 583  ? 157.593 139.203 117.854 1.00 66.71  ? 705  HIS A CA  1 
ATOM   3738 C C   . HIS A 1 583  ? 157.353 138.914 116.383 1.00 68.37  ? 705  HIS A C   1 
ATOM   3739 O O   . HIS A 1 583  ? 157.436 139.815 115.546 1.00 72.21  ? 705  HIS A O   1 
ATOM   3740 C CB  . HIS A 1 583  ? 156.377 139.909 118.463 1.00 67.51  ? 705  HIS A CB  1 
ATOM   3741 C CG  . HIS A 1 583  ? 155.218 139.003 118.735 1.00 70.72  ? 705  HIS A CG  1 
ATOM   3742 N ND1 . HIS A 1 583  ? 154.378 138.547 117.742 1.00 75.95  ? 705  HIS A ND1 1 
ATOM   3743 C CD2 . HIS A 1 583  ? 154.756 138.473 119.891 1.00 77.65  ? 705  HIS A CD2 1 
ATOM   3744 C CE1 . HIS A 1 583  ? 153.450 137.773 118.275 1.00 77.61  ? 705  HIS A CE1 1 
ATOM   3745 N NE2 . HIS A 1 583  ? 153.658 137.710 119.577 1.00 81.12  ? 705  HIS A NE2 1 
ATOM   3746 N N   . ARG A 1 584  ? 157.059 137.658 116.073 1.00 70.40  ? 706  ARG A N   1 
ATOM   3747 C CA  . ARG A 1 584  ? 156.675 137.264 114.724 1.00 70.33  ? 706  ARG A CA  1 
ATOM   3748 C C   . ARG A 1 584  ? 155.158 137.287 114.652 1.00 69.40  ? 706  ARG A C   1 
ATOM   3749 O O   . ARG A 1 584  ? 154.482 136.635 115.453 1.00 76.81  ? 706  ARG A O   1 
ATOM   3750 C CB  . ARG A 1 584  ? 157.225 135.888 114.375 1.00 79.70  ? 706  ARG A CB  1 
ATOM   3751 C CG  . ARG A 1 584  ? 156.758 135.367 113.035 1.00 76.49  ? 706  ARG A CG  1 
ATOM   3752 C CD  . ARG A 1 584  ? 156.822 133.861 113.011 1.00 88.04  ? 706  ARG A CD  1 
ATOM   3753 N NE  . ARG A 1 584  ? 158.190 133.376 112.898 1.00 97.87  ? 706  ARG A NE  1 
ATOM   3754 C CZ  . ARG A 1 584  ? 158.724 132.448 113.680 1.00 103.31 ? 706  ARG A CZ  1 
ATOM   3755 N NH1 . ARG A 1 584  ? 158.037 131.898 114.668 1.00 99.21  ? 706  ARG A NH1 1 
ATOM   3756 N NH2 . ARG A 1 584  ? 159.981 132.068 113.471 1.00 105.45 ? 706  ARG A NH2 1 
ATOM   3757 N N   . LEU A 1 585  ? 154.620 138.035 113.692 1.00 68.85  ? 707  LEU A N   1 
ATOM   3758 C CA  . LEU A 1 585  ? 153.185 138.283 113.691 1.00 70.29  ? 707  LEU A CA  1 
ATOM   3759 C C   . LEU A 1 585  ? 152.436 137.218 112.905 1.00 70.87  ? 707  LEU A C   1 
ATOM   3760 O O   . LEU A 1 585  ? 151.305 136.864 113.256 1.00 74.33  ? 707  LEU A O   1 
ATOM   3761 C CB  . LEU A 1 585  ? 152.893 139.671 113.121 1.00 69.49  ? 707  LEU A CB  1 
ATOM   3762 C CG  . LEU A 1 585  ? 153.545 140.895 113.771 1.00 64.74  ? 707  LEU A CG  1 
ATOM   3763 C CD1 . LEU A 1 585  ? 152.900 142.147 113.245 1.00 58.28  ? 707  LEU A CD1 1 
ATOM   3764 C CD2 . LEU A 1 585  ? 153.447 140.862 115.284 1.00 64.45  ? 707  LEU A CD2 1 
ATOM   3765 N N   . LEU A 1 586  ? 153.055 136.681 111.859 1.00 70.25  ? 708  LEU A N   1 
ATOM   3766 C CA  . LEU A 1 586  ? 152.342 135.863 110.895 1.00 71.93  ? 708  LEU A CA  1 
ATOM   3767 C C   . LEU A 1 586  ? 153.322 134.962 110.162 1.00 79.87  ? 708  LEU A C   1 
ATOM   3768 O O   . LEU A 1 586  ? 154.455 135.363 109.902 1.00 81.00  ? 708  LEU A O   1 
ATOM   3769 C CB  . LEU A 1 586  ? 151.594 136.763 109.910 1.00 66.02  ? 708  LEU A CB  1 
ATOM   3770 C CG  . LEU A 1 586  ? 150.641 136.201 108.869 1.00 77.20  ? 708  LEU A CG  1 
ATOM   3771 C CD1 . LEU A 1 586  ? 149.411 135.649 109.522 1.00 81.55  ? 708  LEU A CD1 1 
ATOM   3772 C CD2 . LEU A 1 586  ? 150.273 137.341 107.980 1.00 73.30  ? 708  LEU A CD2 1 
ATOM   3773 N N   . ARG A 1 587  ? 152.885 133.744 109.846 1.00 84.84  ? 709  ARG A N   1 
ATOM   3774 C CA  . ARG A 1 587  ? 153.579 132.864 108.911 1.00 83.28  ? 709  ARG A CA  1 
ATOM   3775 C C   . ARG A 1 587  ? 152.636 132.602 107.747 1.00 89.86  ? 709  ARG A C   1 
ATOM   3776 O O   . ARG A 1 587  ? 151.622 131.916 107.908 1.00 97.60  ? 709  ARG A O   1 
ATOM   3777 C CB  . ARG A 1 587  ? 153.998 131.550 109.561 1.00 89.56  ? 709  ARG A CB  1 
ATOM   3778 C CG  . ARG A 1 587  ? 155.208 131.638 110.456 1.00 95.73  ? 709  ARG A CG  1 
ATOM   3779 C CD  . ARG A 1 587  ? 155.626 130.260 110.946 1.00 106.07 ? 709  ARG A CD  1 
ATOM   3780 N NE  . ARG A 1 587  ? 154.596 129.637 111.769 1.00 113.55 ? 709  ARG A NE  1 
ATOM   3781 C CZ  . ARG A 1 587  ? 154.505 129.762 113.085 1.00 114.31 ? 709  ARG A CZ  1 
ATOM   3782 N NH1 . ARG A 1 587  ? 155.366 130.497 113.770 1.00 112.03 ? 709  ARG A NH1 1 
ATOM   3783 N NH2 . ARG A 1 587  ? 153.522 129.141 113.731 1.00 111.79 ? 709  ARG A NH2 1 
ATOM   3784 N N   . ILE A 1 588  ? 152.969 133.142 106.579 1.00 85.93  ? 710  ILE A N   1 
ATOM   3785 C CA  . ILE A 1 588  ? 152.177 132.919 105.379 1.00 88.28  ? 710  ILE A CA  1 
ATOM   3786 C C   . ILE A 1 588  ? 153.149 132.825 104.206 1.00 89.69  ? 710  ILE A C   1 
ATOM   3787 O O   . ILE A 1 588  ? 154.215 133.447 104.206 1.00 86.43  ? 710  ILE A O   1 
ATOM   3788 C CB  . ILE A 1 588  ? 151.083 134.022 105.229 1.00 88.00  ? 710  ILE A CB  1 
ATOM   3789 C CG1 . ILE A 1 588  ? 150.031 133.666 104.171 1.00 95.23  ? 710  ILE A CG1 1 
ATOM   3790 C CG2 . ILE A 1 588  ? 151.665 135.423 105.014 1.00 88.65  ? 710  ILE A CG2 1 
ATOM   3791 C CD1 . ILE A 1 588  ? 149.193 132.464 104.542 1.00 91.09  ? 710  ILE A CD1 1 
ATOM   3792 N N   . ARG A 1 589  ? 152.826 131.964 103.246 1.00 94.47  ? 711  ARG A N   1 
ATOM   3793 C CA  . ARG A 1 589  ? 153.723 131.769 102.119 1.00 99.70  ? 711  ARG A CA  1 
ATOM   3794 C C   . ARG A 1 589  ? 153.569 132.911 101.126 1.00 99.38  ? 711  ARG A C   1 
ATOM   3795 O O   . ARG A 1 589  ? 152.467 133.197 100.644 1.00 95.29  ? 711  ARG A O   1 
ATOM   3796 C CB  . ARG A 1 589  ? 153.464 130.426 101.439 1.00 103.26 ? 711  ARG A CB  1 
ATOM   3797 C CG  . ARG A 1 589  ? 154.411 130.161 100.273 1.00 108.81 ? 711  ARG A CG  1 
ATOM   3798 C CD  . ARG A 1 589  ? 153.805 129.312 99.169  1.00 114.66 ? 711  ARG A CD  1 
ATOM   3799 N NE  . ARG A 1 589  ? 154.620 129.360 97.961  1.00 125.12 ? 711  ARG A NE  1 
ATOM   3800 C CZ  . ARG A 1 589  ? 154.273 128.826 96.798  1.00 128.61 ? 711  ARG A CZ  1 
ATOM   3801 N NH1 . ARG A 1 589  ? 153.128 128.179 96.650  1.00 129.07 ? 711  ARG A NH1 1 
ATOM   3802 N NH2 . ARG A 1 589  ? 155.102 128.927 95.764  1.00 129.39 ? 711  ARG A NH2 1 
ATOM   3803 N N   . GLN A 1 590  ? 154.698 133.571 100.848 1.00 99.04  ? 712  GLN A N   1 
ATOM   3804 C CA  . GLN A 1 590  ? 154.952 134.684 99.930  1.00 94.67  ? 712  GLN A CA  1 
ATOM   3805 C C   . GLN A 1 590  ? 154.056 135.902 100.145 1.00 90.92  ? 712  GLN A C   1 
ATOM   3806 O O   . GLN A 1 590  ? 153.148 136.137 99.330  1.00 91.76  ? 712  GLN A O   1 
ATOM   3807 C CB  . GLN A 1 590  ? 154.813 134.189 98.487  1.00 101.61 ? 712  GLN A CB  1 
ATOM   3808 C CG  . GLN A 1 590  ? 155.845 133.157 98.107  1.00 105.99 ? 712  GLN A CG  1 
ATOM   3809 C CD  . GLN A 1 590  ? 157.247 133.700 98.179  1.00 111.93 ? 712  GLN A CD  1 
ATOM   3810 O OE1 . GLN A 1 590  ? 158.015 133.330 99.061  1.00 111.92 ? 712  GLN A OE1 1 
ATOM   3811 N NE2 . GLN A 1 590  ? 157.585 134.599 97.266  1.00 114.11 ? 712  GLN A NE2 1 
ATOM   3812 N N   . PRO A 1 591  ? 154.257 136.705 101.194 1.00 82.75  ? 713  PRO A N   1 
ATOM   3813 C CA  . PRO A 1 591  ? 153.414 137.896 101.366 1.00 77.41  ? 713  PRO A CA  1 
ATOM   3814 C C   . PRO A 1 591  ? 153.853 139.044 100.462 1.00 74.52  ? 713  PRO A C   1 
ATOM   3815 O O   . PRO A 1 591  ? 155.032 139.208 100.138 1.00 76.76  ? 713  PRO A O   1 
ATOM   3816 C CB  . PRO A 1 591  ? 153.595 138.242 102.846 1.00 72.30  ? 713  PRO A CB  1 
ATOM   3817 C CG  . PRO A 1 591  ? 154.960 137.770 103.168 1.00 69.53  ? 713  PRO A CG  1 
ATOM   3818 C CD  . PRO A 1 591  ? 155.257 136.599 102.274 1.00 78.14  ? 713  PRO A CD  1 
ATOM   3819 N N   . GLY A 1 592  ? 152.877 139.834 100.048 1.00 70.20  ? 714  GLY A N   1 
ATOM   3820 C CA  . GLY A 1 592  ? 153.092 140.989 99.185  1.00 64.96  ? 714  GLY A CA  1 
ATOM   3821 C C   . GLY A 1 592  ? 153.250 142.257 99.991  1.00 61.59  ? 714  GLY A C   1 
ATOM   3822 O O   . GLY A 1 592  ? 153.796 142.236 101.093 1.00 60.78  ? 714  GLY A O   1 
ATOM   3823 N N   . TRP A 1 593  ? 152.752 143.364 99.440  1.00 59.60  ? 715  TRP A N   1 
ATOM   3824 C CA  . TRP A 1 593  ? 152.921 144.679 100.049 1.00 52.38  ? 715  TRP A CA  1 
ATOM   3825 C C   . TRP A 1 593  ? 152.073 144.831 101.306 1.00 54.94  ? 715  TRP A C   1 
ATOM   3826 O O   . TRP A 1 593  ? 150.912 144.424 101.339 1.00 68.49  ? 715  TRP A O   1 
ATOM   3827 C CB  . TRP A 1 593  ? 152.545 145.762 99.041  1.00 53.37  ? 715  TRP A CB  1 
ATOM   3828 C CG  . TRP A 1 593  ? 152.890 147.141 99.471  1.00 52.26  ? 715  TRP A CG  1 
ATOM   3829 C CD1 . TRP A 1 593  ? 152.047 148.061 100.013 1.00 56.20  ? 715  TRP A CD1 1 
ATOM   3830 C CD2 . TRP A 1 593  ? 154.168 147.771 99.378  1.00 51.81  ? 715  TRP A CD2 1 
ATOM   3831 N NE1 . TRP A 1 593  ? 152.722 149.224 100.277 1.00 57.97  ? 715  TRP A NE1 1 
ATOM   3832 C CE2 . TRP A 1 593  ? 154.028 149.074 99.895  1.00 55.37  ? 715  TRP A CE2 1 
ATOM   3833 C CE3 . TRP A 1 593  ? 155.423 147.360 98.911  1.00 52.54  ? 715  TRP A CE3 1 
ATOM   3834 C CZ2 . TRP A 1 593  ? 155.093 149.968 99.959  1.00 54.58  ? 715  TRP A CZ2 1 
ATOM   3835 C CZ3 . TRP A 1 593  ? 156.482 148.249 98.976  1.00 52.78  ? 715  TRP A CZ3 1 
ATOM   3836 C CH2 . TRP A 1 593  ? 156.310 149.539 99.498  1.00 53.31  ? 715  TRP A CH2 1 
ATOM   3837 N N   . PHE A 1 594  ? 152.675 145.372 102.362 1.00 49.18  ? 716  PHE A N   1 
ATOM   3838 C CA  . PHE A 1 594  ? 151.947 145.658 103.588 1.00 49.24  ? 716  PHE A CA  1 
ATOM   3839 C C   . PHE A 1 594  ? 152.054 147.135 103.927 1.00 54.54  ? 716  PHE A C   1 
ATOM   3840 O O   . PHE A 1 594  ? 153.079 147.774 103.674 1.00 60.93  ? 716  PHE A O   1 
ATOM   3841 C CB  . PHE A 1 594  ? 152.402 144.777 104.778 1.00 47.50  ? 716  PHE A CB  1 
ATOM   3842 C CG  . PHE A 1 594  ? 153.731 145.148 105.392 1.00 51.89  ? 716  PHE A CG  1 
ATOM   3843 C CD1 . PHE A 1 594  ? 154.924 144.757 104.787 1.00 58.51  ? 716  PHE A CD1 1 
ATOM   3844 C CD2 . PHE A 1 594  ? 153.783 145.810 106.623 1.00 52.03  ? 716  PHE A CD2 1 
ATOM   3845 C CE1 . PHE A 1 594  ? 156.151 145.068 105.369 1.00 57.68  ? 716  PHE A CE1 1 
ATOM   3846 C CE2 . PHE A 1 594  ? 155.001 146.129 107.210 1.00 49.56  ? 716  PHE A CE2 1 
ATOM   3847 C CZ  . PHE A 1 594  ? 156.183 145.751 106.581 1.00 56.34  ? 716  PHE A CZ  1 
ATOM   3848 N N   . LEU A 1 595  ? 150.976 147.667 104.491 1.00 57.93  ? 717  LEU A N   1 
ATOM   3849 C CA  . LEU A 1 595  ? 150.862 149.077 104.818 1.00 52.43  ? 717  LEU A CA  1 
ATOM   3850 C C   . LEU A 1 595  ? 150.378 149.181 106.255 1.00 56.42  ? 717  LEU A C   1 
ATOM   3851 O O   . LEU A 1 595  ? 149.571 148.363 106.701 1.00 61.85  ? 717  LEU A O   1 
ATOM   3852 C CB  . LEU A 1 595  ? 149.923 149.770 103.820 1.00 49.57  ? 717  LEU A CB  1 
ATOM   3853 C CG  . LEU A 1 595  ? 149.664 151.274 103.708 1.00 68.13  ? 717  LEU A CG  1 
ATOM   3854 C CD1 . LEU A 1 595  ? 149.274 151.551 102.282 1.00 73.84  ? 717  LEU A CD1 1 
ATOM   3855 C CD2 . LEU A 1 595  ? 148.538 151.752 104.593 1.00 67.96  ? 717  LEU A CD2 1 
ATOM   3856 N N   . VAL A 1 596  ? 150.871 150.183 106.969 1.00 60.29  ? 718  VAL A N   1 
ATOM   3857 C CA  . VAL A 1 596  ? 150.725 150.275 108.416 1.00 59.59  ? 718  VAL A CA  1 
ATOM   3858 C C   . VAL A 1 596  ? 149.853 151.484 108.740 1.00 66.51  ? 718  VAL A C   1 
ATOM   3859 O O   . VAL A 1 596  ? 150.149 152.603 108.308 1.00 70.85  ? 718  VAL A O   1 
ATOM   3860 C CB  . VAL A 1 596  ? 152.102 150.371 109.092 1.00 55.93  ? 718  VAL A CB  1 
ATOM   3861 C CG1 . VAL A 1 596  ? 151.983 150.685 110.553 1.00 55.06  ? 718  VAL A CG1 1 
ATOM   3862 C CG2 . VAL A 1 596  ? 152.871 149.078 108.902 1.00 59.35  ? 718  VAL A CG2 1 
ATOM   3863 N N   . GLN A 1 597  ? 148.757 151.252 109.475 1.00 65.68  ? 719  GLN A N   1 
ATOM   3864 C CA  . GLN A 1 597  ? 147.952 152.322 110.049 1.00 62.29  ? 719  GLN A CA  1 
ATOM   3865 C C   . GLN A 1 597  ? 148.402 152.556 111.481 1.00 62.47  ? 719  GLN A C   1 
ATOM   3866 O O   . GLN A 1 597  ? 148.172 151.688 112.336 1.00 65.21  ? 719  GLN A O   1 
ATOM   3867 C CB  . GLN A 1 597  ? 146.467 151.964 110.015 1.00 67.47  ? 719  GLN A CB  1 
ATOM   3868 C CG  . GLN A 1 597  ? 145.848 151.839 108.637 1.00 72.01  ? 719  GLN A CG  1 
ATOM   3869 C CD  . GLN A 1 597  ? 145.881 153.142 107.869 1.00 81.49  ? 719  GLN A CD  1 
ATOM   3870 O OE1 . GLN A 1 597  ? 146.623 153.291 106.904 1.00 83.87  ? 719  GLN A OE1 1 
ATOM   3871 N NE2 . GLN A 1 597  ? 145.064 154.097 108.293 1.00 85.79  ? 719  GLN A NE2 1 
ATOM   3872 N N   . PRO A 1 598  ? 149.038 153.688 111.802 1.00 58.51  ? 720  PRO A N   1 
ATOM   3873 C CA  . PRO A 1 598  ? 149.501 153.910 113.176 1.00 57.31  ? 720  PRO A CA  1 
ATOM   3874 C C   . PRO A 1 598  ? 148.397 154.330 114.128 1.00 62.33  ? 720  PRO A C   1 
ATOM   3875 O O   . PRO A 1 598  ? 148.470 154.060 115.330 1.00 61.21  ? 720  PRO A O   1 
ATOM   3876 C CB  . PRO A 1 598  ? 150.541 155.023 113.015 1.00 56.71  ? 720  PRO A CB  1 
ATOM   3877 C CG  . PRO A 1 598  ? 150.892 155.014 111.565 1.00 55.20  ? 720  PRO A CG  1 
ATOM   3878 C CD  . PRO A 1 598  ? 149.613 154.686 110.890 1.00 59.70  ? 720  PRO A CD  1 
ATOM   3879 N N   . GLN A 1 599  ? 147.375 155.003 113.599 1.00 61.18  ? 721  GLN A N   1 
ATOM   3880 C CA  . GLN A 1 599  ? 146.275 155.472 114.433 1.00 60.23  ? 721  GLN A CA  1 
ATOM   3881 C C   . GLN A 1 599  ? 145.331 154.339 114.806 1.00 66.42  ? 721  GLN A C   1 
ATOM   3882 O O   . GLN A 1 599  ? 144.775 154.329 115.909 1.00 71.05  ? 721  GLN A O   1 
ATOM   3883 C CB  . GLN A 1 599  ? 145.500 156.571 113.711 1.00 65.21  ? 721  GLN A CB  1 
ATOM   3884 C CG  . GLN A 1 599  ? 146.357 157.685 113.158 1.00 66.09  ? 721  GLN A CG  1 
ATOM   3885 C CD  . GLN A 1 599  ? 146.580 157.546 111.669 1.00 73.98  ? 721  GLN A CD  1 
ATOM   3886 O OE1 . GLN A 1 599  ? 145.936 156.735 111.006 1.00 75.43  ? 721  GLN A OE1 1 
ATOM   3887 N NE2 . GLN A 1 599  ? 147.492 158.342 111.133 1.00 74.61  ? 721  GLN A NE2 1 
ATOM   3888 N N   . HIS A 1 600  ? 145.138 153.382 113.905 1.00 63.71  ? 722  HIS A N   1 
ATOM   3889 C CA  . HIS A 1 600  ? 144.155 152.330 114.094 1.00 59.47  ? 722  HIS A CA  1 
ATOM   3890 C C   . HIS A 1 600  ? 144.762 151.005 114.524 1.00 59.96  ? 722  HIS A C   1 
ATOM   3891 O O   . HIS A 1 600  ? 143.997 150.066 114.777 1.00 69.13  ? 722  HIS A O   1 
ATOM   3892 C CB  . HIS A 1 600  ? 143.350 152.133 112.811 1.00 62.73  ? 722  HIS A CB  1 
ATOM   3893 C CG  . HIS A 1 600  ? 142.752 153.395 112.278 1.00 70.60  ? 722  HIS A CG  1 
ATOM   3894 N ND1 . HIS A 1 600  ? 142.697 153.682 110.932 1.00 80.90  ? 722  HIS A ND1 1 
ATOM   3895 C CD2 . HIS A 1 600  ? 142.187 154.449 112.911 1.00 71.92  ? 722  HIS A CD2 1 
ATOM   3896 C CE1 . HIS A 1 600  ? 142.121 154.858 110.758 1.00 83.07  ? 722  HIS A CE1 1 
ATOM   3897 N NE2 . HIS A 1 600  ? 141.803 155.345 111.944 1.00 80.87  ? 722  HIS A NE2 1 
ATOM   3898 N N   . PHE A 1 601  ? 146.105 150.926 114.603 1.00 54.19  ? 723  PHE A N   1 
ATOM   3899 C CA  . PHE A 1 601  ? 146.908 149.770 115.055 1.00 49.86  ? 723  PHE A CA  1 
ATOM   3900 C C   . PHE A 1 601  ? 146.668 148.508 114.228 1.00 56.28  ? 723  PHE A C   1 
ATOM   3901 O O   . PHE A 1 601  ? 146.685 147.395 114.756 1.00 62.67  ? 723  PHE A O   1 
ATOM   3902 C CB  . PHE A 1 601  ? 146.721 149.479 116.551 1.00 49.81  ? 723  PHE A CB  1 
ATOM   3903 C CG  . PHE A 1 601  ? 146.820 150.694 117.417 1.00 55.82  ? 723  PHE A CG  1 
ATOM   3904 C CD1 . PHE A 1 601  ? 148.069 151.213 117.745 1.00 56.64  ? 723  PHE A CD1 1 
ATOM   3905 C CD2 . PHE A 1 601  ? 145.672 151.330 117.894 1.00 62.68  ? 723  PHE A CD2 1 
ATOM   3906 C CE1 . PHE A 1 601  ? 148.181 152.341 118.548 1.00 56.46  ? 723  PHE A CE1 1 
ATOM   3907 C CE2 . PHE A 1 601  ? 145.774 152.475 118.684 1.00 66.98  ? 723  PHE A CE2 1 
ATOM   3908 C CZ  . PHE A 1 601  ? 147.032 152.969 119.014 1.00 62.83  ? 723  PHE A CZ  1 
ATOM   3909 N N   . ILE A 1 602  ? 146.430 148.678 112.928 1.00 58.20  ? 724  ILE A N   1 
ATOM   3910 C CA  . ILE A 1 602  ? 146.115 147.593 112.004 1.00 52.24  ? 724  ILE A CA  1 
ATOM   3911 C C   . ILE A 1 602  ? 147.080 147.642 110.825 1.00 57.42  ? 724  ILE A C   1 
ATOM   3912 O O   . ILE A 1 602  ? 147.214 148.680 110.171 1.00 61.79  ? 724  ILE A O   1 
ATOM   3913 C CB  . ILE A 1 602  ? 144.650 147.667 111.518 1.00 53.69  ? 724  ILE A CB  1 
ATOM   3914 C CG1 . ILE A 1 602  ? 143.661 147.473 112.667 1.00 52.57  ? 724  ILE A CG1 1 
ATOM   3915 C CG2 . ILE A 1 602  ? 144.362 146.696 110.418 1.00 60.80  ? 724  ILE A CG2 1 
ATOM   3916 C CD1 . ILE A 1 602  ? 142.266 147.778 112.307 1.00 60.18  ? 724  ILE A CD1 1 
ATOM   3917 N N   . ILE A 1 603  ? 147.757 146.523 110.564 1.00 55.53  ? 725  ILE A N   1 
ATOM   3918 C CA  . ILE A 1 603  ? 148.509 146.312 109.335 1.00 51.07  ? 725  ILE A CA  1 
ATOM   3919 C C   . ILE A 1 603  ? 147.599 145.646 108.311 1.00 54.09  ? 725  ILE A C   1 
ATOM   3920 O O   . ILE A 1 603  ? 147.019 144.589 108.581 1.00 61.18  ? 725  ILE A O   1 
ATOM   3921 C CB  . ILE A 1 603  ? 149.753 145.452 109.594 1.00 55.89  ? 725  ILE A CB  1 
ATOM   3922 C CG1 . ILE A 1 603  ? 150.588 146.062 110.712 1.00 57.69  ? 725  ILE A CG1 1 
ATOM   3923 C CG2 . ILE A 1 603  ? 150.568 145.296 108.338 1.00 60.17  ? 725  ILE A CG2 1 
ATOM   3924 C CD1 . ILE A 1 603  ? 151.606 145.125 111.253 1.00 53.03  ? 725  ILE A CD1 1 
ATOM   3925 N N   . HIS A 1 604  ? 147.467 146.263 107.141 1.00 60.56  ? 726  HIS A N   1 
ATOM   3926 C CA  . HIS A 1 604  ? 146.791 145.660 105.999 1.00 56.71  ? 726  HIS A CA  1 
ATOM   3927 C C   . HIS A 1 604  ? 147.858 145.058 105.098 1.00 55.51  ? 726  HIS A C   1 
ATOM   3928 O O   . HIS A 1 604  ? 148.760 145.765 104.654 1.00 63.37  ? 726  HIS A O   1 
ATOM   3929 C CB  . HIS A 1 604  ? 145.968 146.694 105.237 1.00 55.16  ? 726  HIS A CB  1 
ATOM   3930 C CG  . HIS A 1 604  ? 144.677 147.049 105.900 1.00 61.47  ? 726  HIS A CG  1 
ATOM   3931 N ND1 . HIS A 1 604  ? 144.545 148.133 106.738 1.00 60.06  ? 726  HIS A ND1 1 
ATOM   3932 C CD2 . HIS A 1 604  ? 143.456 146.472 105.835 1.00 75.01  ? 726  HIS A CD2 1 
ATOM   3933 C CE1 . HIS A 1 604  ? 143.300 148.201 107.172 1.00 75.19  ? 726  HIS A CE1 1 
ATOM   3934 N NE2 . HIS A 1 604  ? 142.618 147.205 106.637 1.00 79.23  ? 726  HIS A NE2 1 
ATOM   3935 N N   . LEU A 1 605  ? 147.758 143.761 104.829 1.00 58.34  ? 727  LEU A N   1 
ATOM   3936 C CA  . LEU A 1 605  ? 148.735 143.050 104.014 1.00 56.99  ? 727  LEU A CA  1 
ATOM   3937 C C   . LEU A 1 605  ? 148.044 142.366 102.848 1.00 66.13  ? 727  LEU A C   1 
ATOM   3938 O O   . LEU A 1 605  ? 147.040 141.671 103.032 1.00 77.42  ? 727  LEU A O   1 
ATOM   3939 C CB  . LEU A 1 605  ? 149.498 142.022 104.846 1.00 54.23  ? 727  LEU A CB  1 
ATOM   3940 C CG  . LEU A 1 605  ? 150.298 140.889 104.201 1.00 60.64  ? 727  LEU A CG  1 
ATOM   3941 C CD1 . LEU A 1 605  ? 151.471 141.385 103.393 1.00 63.15  ? 727  LEU A CD1 1 
ATOM   3942 C CD2 . LEU A 1 605  ? 150.776 139.942 105.268 1.00 65.34  ? 727  LEU A CD2 1 
ATOM   3943 N N   . MET A 1 606  ? 148.593 142.557 101.659 1.00 62.43  ? 728  MET A N   1 
ATOM   3944 C CA  . MET A 1 606  ? 148.089 141.937 100.449 1.00 67.62  ? 728  MET A CA  1 
ATOM   3945 C C   . MET A 1 606  ? 148.802 140.613 100.224 1.00 74.49  ? 728  MET A C   1 
ATOM   3946 O O   . MET A 1 606  ? 150.014 140.512 100.416 1.00 76.24  ? 728  MET A O   1 
ATOM   3947 C CB  . MET A 1 606  ? 148.313 142.878 99.266  1.00 68.31  ? 728  MET A CB  1 
ATOM   3948 C CG  . MET A 1 606  ? 147.795 142.407 97.934  1.00 81.28  ? 728  MET A CG  1 
ATOM   3949 S SD  . MET A 1 606  ? 148.149 143.670 96.721  1.00 109.01 ? 728  MET A SD  1 
ATOM   3950 C CE  . MET A 1 606  ? 149.914 143.441 96.626  1.00 81.24  ? 728  MET A CE  1 
ATOM   3951 N N   . LEU A 1 607  ? 148.044 139.585 99.851  1.00 86.67  ? 729  LEU A N   1 
ATOM   3952 C CA  . LEU A 1 607  ? 148.618 138.299 99.454  1.00 87.61  ? 729  LEU A CA  1 
ATOM   3953 C C   . LEU A 1 607  ? 148.398 138.106 97.959  1.00 93.12  ? 729  LEU A C   1 
ATOM   3954 O O   . LEU A 1 607  ? 147.264 137.829 97.529  1.00 94.28  ? 729  LEU A O   1 
ATOM   3955 C CB  . LEU A 1 607  ? 148.003 137.153 100.248 1.00 84.45  ? 729  LEU A CB  1 
ATOM   3956 C CG  . LEU A 1 607  ? 148.207 137.254 101.758 1.00 78.83  ? 729  LEU A CG  1 
ATOM   3957 C CD1 . LEU A 1 607  ? 147.219 136.371 102.487 1.00 84.97  ? 729  LEU A CD1 1 
ATOM   3958 C CD2 . LEU A 1 607  ? 149.628 136.892 102.127 1.00 78.96  ? 729  LEU A CD2 1 
ATOM   3959 N N   . PRO A 1 608  ? 149.440 138.250 97.120  1.00 95.29  ? 730  PRO A N   1 
ATOM   3960 C CA  . PRO A 1 608  ? 149.214 138.269 95.668  1.00 96.03  ? 730  PRO A CA  1 
ATOM   3961 C C   . PRO A 1 608  ? 149.036 136.897 95.027  1.00 104.14 ? 730  PRO A C   1 
ATOM   3962 O O   . PRO A 1 608  ? 148.284 136.771 94.055  1.00 103.76 ? 730  PRO A O   1 
ATOM   3963 C CB  . PRO A 1 608  ? 150.465 138.977 95.134  1.00 90.90  ? 730  PRO A CB  1 
ATOM   3964 C CG  . PRO A 1 608  ? 151.521 138.722 96.145  1.00 93.81  ? 730  PRO A CG  1 
ATOM   3965 C CD  . PRO A 1 608  ? 150.851 138.497 97.470  1.00 92.58  ? 730  PRO A CD  1 
ATOM   3966 N N   . GLN A 1 609  ? 149.719 135.871 95.543  1.00 105.80 ? 731  GLN A N   1 
ATOM   3967 C CA  . GLN A 1 609  ? 149.610 134.535 94.966  1.00 106.15 ? 731  GLN A CA  1 
ATOM   3968 C C   . GLN A 1 609  ? 148.306 133.859 95.362  1.00 106.33 ? 731  GLN A C   1 
ATOM   3969 O O   . GLN A 1 609  ? 147.690 133.166 94.545  1.00 110.08 ? 731  GLN A O   1 
ATOM   3970 C CB  . GLN A 1 609  ? 150.803 133.680 95.387  1.00 104.91 ? 731  GLN A CB  1 
ATOM   3971 C CG  . GLN A 1 609  ? 152.137 134.189 94.879  1.00 106.63 ? 731  GLN A CG  1 
ATOM   3972 C CD  . GLN A 1 609  ? 153.281 133.260 95.224  1.00 118.54 ? 731  GLN A CD  1 
ATOM   3973 O OE1 . GLN A 1 609  ? 153.157 132.405 96.100  1.00 117.32 ? 731  GLN A OE1 1 
ATOM   3974 N NE2 . GLN A 1 609  ? 154.403 133.421 94.533  1.00 119.20 ? 731  GLN A NE2 1 
ATOM   3975 N N   . GLU A 1 610  ? 147.868 134.054 96.604  1.00 102.91 ? 732  GLU A N   1 
ATOM   3976 C CA  . GLU A 1 610  ? 146.591 133.512 97.046  1.00 103.77 ? 732  GLU A CA  1 
ATOM   3977 C C   . GLU A 1 610  ? 145.408 134.358 96.604  1.00 102.67 ? 732  GLU A C   1 
ATOM   3978 O O   . GLU A 1 610  ? 144.270 133.881 96.667  1.00 104.35 ? 732  GLU A O   1 
ATOM   3979 C CB  . GLU A 1 610  ? 146.588 133.363 98.567  1.00 99.10  ? 732  GLU A CB  1 
ATOM   3980 C CG  . GLU A 1 610  ? 147.853 132.730 99.108  1.00 101.59 ? 732  GLU A CG  1 
ATOM   3981 C CD  . GLU A 1 610  ? 147.823 132.557 100.609 1.00 102.64 ? 732  GLU A CD  1 
ATOM   3982 O OE1 . GLU A 1 610  ? 146.758 132.788 101.219 1.00 99.07  ? 732  GLU A OE1 1 
ATOM   3983 O OE2 . GLU A 1 610  ? 148.869 132.183 101.177 1.00 105.88 ? 732  GLU A OE2 1 
ATOM   3984 N N   . GLY A 1 611  ? 145.643 135.592 96.167  1.00 99.67  ? 733  GLY A N   1 
ATOM   3985 C CA  . GLY A 1 611  ? 144.591 136.416 95.615  1.00 98.65  ? 733  GLY A CA  1 
ATOM   3986 C C   . GLY A 1 611  ? 143.712 137.116 96.623  1.00 98.77  ? 733  GLY A C   1 
ATOM   3987 O O   . GLY A 1 611  ? 142.734 137.757 96.221  1.00 102.74 ? 733  GLY A O   1 
ATOM   3988 N N   . LYS A 1 612  ? 144.014 137.019 97.911  1.00 97.06  ? 734  LYS A N   1 
ATOM   3989 C CA  . LYS A 1 612  ? 143.216 137.666 98.939  1.00 98.20  ? 734  LYS A CA  1 
ATOM   3990 C C   . LYS A 1 612  ? 144.007 138.798 99.589  1.00 91.06  ? 734  LYS A C   1 
ATOM   3991 O O   . LYS A 1 612  ? 145.152 139.084 99.234  1.00 91.28  ? 734  LYS A O   1 
ATOM   3992 C CB  . LYS A 1 612  ? 142.735 136.652 99.981  1.00 100.11 ? 734  LYS A CB  1 
ATOM   3993 C CG  . LYS A 1 612  ? 143.831 136.007 100.801 1.00 95.31  ? 734  LYS A CG  1 
ATOM   3994 C CD  . LYS A 1 612  ? 143.246 135.052 101.830 1.00 96.52  ? 734  LYS A CD  1 
ATOM   3995 C CE  . LYS A 1 612  ? 142.702 133.792 101.178 1.00 102.55 ? 734  LYS A CE  1 
ATOM   3996 N NZ  . LYS A 1 612  ? 143.775 132.967 100.562 1.00 103.35 ? 734  LYS A NZ  1 
ATOM   3997 N N   . PHE A 1 613  ? 143.368 139.437 100.563 1.00 86.25  ? 735  PHE A N   1 
ATOM   3998 C CA  . PHE A 1 613  ? 143.849 140.666 101.180 1.00 80.34  ? 735  PHE A CA  1 
ATOM   3999 C C   . PHE A 1 613  ? 143.550 140.562 102.665 1.00 80.71  ? 735  PHE A C   1 
ATOM   4000 O O   . PHE A 1 613  ? 142.407 140.302 103.040 1.00 89.36  ? 735  PHE A O   1 
ATOM   4001 C CB  . PHE A 1 613  ? 143.149 141.865 100.538 1.00 86.12  ? 735  PHE A CB  1 
ATOM   4002 C CG  . PHE A 1 613  ? 143.555 143.185 101.091 1.00 77.30  ? 735  PHE A CG  1 
ATOM   4003 C CD1 . PHE A 1 613  ? 144.796 143.731 100.775 1.00 74.40  ? 735  PHE A CD1 1 
ATOM   4004 C CD2 . PHE A 1 613  ? 142.671 143.904 101.894 1.00 81.22  ? 735  PHE A CD2 1 
ATOM   4005 C CE1 . PHE A 1 613  ? 145.170 144.968 101.280 1.00 75.93  ? 735  PHE A CE1 1 
ATOM   4006 C CE2 . PHE A 1 613  ? 143.028 145.144 102.406 1.00 84.34  ? 735  PHE A CE2 1 
ATOM   4007 C CZ  . PHE A 1 613  ? 144.278 145.674 102.098 1.00 81.43  ? 735  PHE A CZ  1 
ATOM   4008 N N   . LEU A 1 614  ? 144.557 140.727 103.514 1.00 69.21  ? 736  LEU A N   1 
ATOM   4009 C CA  . LEU A 1 614  ? 144.433 140.281 104.893 1.00 66.22  ? 736  LEU A CA  1 
ATOM   4010 C C   . LEU A 1 614  ? 144.757 141.412 105.867 1.00 64.45  ? 736  LEU A C   1 
ATOM   4011 O O   . LEU A 1 614  ? 145.540 142.314 105.560 1.00 72.32  ? 736  LEU A O   1 
ATOM   4012 C CB  . LEU A 1 614  ? 145.318 139.042 105.096 1.00 67.32  ? 736  LEU A CB  1 
ATOM   4013 C CG  . LEU A 1 614  ? 145.818 138.447 106.405 1.00 73.21  ? 736  LEU A CG  1 
ATOM   4014 C CD1 . LEU A 1 614  ? 144.697 137.686 107.064 1.00 74.79  ? 736  LEU A CD1 1 
ATOM   4015 C CD2 . LEU A 1 614  ? 146.971 137.527 106.122 1.00 78.68  ? 736  LEU A CD2 1 
ATOM   4016 N N   . GLU A 1 615  ? 144.126 141.363 107.044 1.00 65.61  ? 737  GLU A N   1 
ATOM   4017 C CA  . GLU A 1 615  ? 143.999 142.481 107.985 1.00 59.73  ? 737  GLU A CA  1 
ATOM   4018 C C   . GLU A 1 615  ? 144.511 142.059 109.365 1.00 59.14  ? 737  GLU A C   1 
ATOM   4019 O O   . GLU A 1 615  ? 143.804 141.361 110.091 1.00 70.16  ? 737  GLU A O   1 
ATOM   4020 C CB  . GLU A 1 615  ? 142.535 142.890 108.032 1.00 70.46  ? 737  GLU A CB  1 
ATOM   4021 C CG  . GLU A 1 615  ? 142.231 144.223 108.614 1.00 70.72  ? 737  GLU A CG  1 
ATOM   4022 C CD  . GLU A 1 615  ? 140.753 144.541 108.586 1.00 86.36  ? 737  GLU A CD  1 
ATOM   4023 O OE1 . GLU A 1 615  ? 139.943 143.592 108.616 1.00 90.54  ? 737  GLU A OE1 1 
ATOM   4024 O OE2 . GLU A 1 615  ? 140.398 145.737 108.545 1.00 90.01  ? 737  GLU A OE2 1 
ATOM   4025 N N   . ILE A 1 616  ? 145.708 142.508 109.750 1.00 55.12  ? 738  ILE A N   1 
ATOM   4026 C CA  . ILE A 1 616  ? 146.409 141.992 110.928 1.00 53.72  ? 738  ILE A CA  1 
ATOM   4027 C C   . ILE A 1 616  ? 146.566 143.137 111.927 1.00 58.88  ? 738  ILE A C   1 
ATOM   4028 O O   . ILE A 1 616  ? 146.880 144.267 111.538 1.00 65.26  ? 738  ILE A O   1 
ATOM   4029 C CB  . ILE A 1 616  ? 147.795 141.386 110.577 1.00 56.01  ? 738  ILE A CB  1 
ATOM   4030 C CG1 . ILE A 1 616  ? 147.730 140.331 109.481 1.00 60.19  ? 738  ILE A CG1 1 
ATOM   4031 C CG2 . ILE A 1 616  ? 148.403 140.592 111.721 1.00 61.09  ? 738  ILE A CG2 1 
ATOM   4032 C CD1 . ILE A 1 616  ? 148.202 140.820 108.149 1.00 62.85  ? 738  ILE A CD1 1 
ATOM   4033 N N   . SER A 1 617  ? 146.346 142.854 113.215 1.00 54.66  ? 739  SER A N   1 
ATOM   4034 C CA  . SER A 1 617  ? 146.677 143.791 114.281 1.00 55.28  ? 739  SER A CA  1 
ATOM   4035 C C   . SER A 1 617  ? 148.172 143.747 114.611 1.00 61.95  ? 739  SER A C   1 
ATOM   4036 O O   . SER A 1 617  ? 148.953 143.011 114.007 1.00 67.84  ? 739  SER A O   1 
ATOM   4037 C CB  . SER A 1 617  ? 145.861 143.488 115.531 1.00 56.85  ? 739  SER A CB  1 
ATOM   4038 O OG  . SER A 1 617  ? 145.964 142.125 115.888 1.00 65.67  ? 739  SER A OG  1 
ATOM   4039 N N   . TYR A 1 618  ? 148.577 144.550 115.602 1.00 58.12  ? 740  TYR A N   1 
ATOM   4040 C CA  . TYR A 1 618  ? 150.002 144.648 115.915 1.00 54.21  ? 740  TYR A CA  1 
ATOM   4041 C C   . TYR A 1 618  ? 150.500 143.484 116.761 1.00 64.44  ? 740  TYR A C   1 
ATOM   4042 O O   . TYR A 1 618  ? 151.713 143.282 116.873 1.00 74.07  ? 740  TYR A O   1 
ATOM   4043 C CB  . TYR A 1 618  ? 150.345 145.957 116.625 1.00 53.94  ? 740  TYR A CB  1 
ATOM   4044 C CG  . TYR A 1 618  ? 150.334 147.212 115.787 1.00 53.03  ? 740  TYR A CG  1 
ATOM   4045 C CD1 . TYR A 1 618  ? 150.281 147.154 114.389 1.00 55.08  ? 740  TYR A CD1 1 
ATOM   4046 C CD2 . TYR A 1 618  ? 150.514 148.454 116.398 1.00 54.73  ? 740  TYR A CD2 1 
ATOM   4047 C CE1 . TYR A 1 618  ? 150.311 148.320 113.630 1.00 55.33  ? 740  TYR A CE1 1 
ATOM   4048 C CE2 . TYR A 1 618  ? 150.555 149.614 115.658 1.00 51.60  ? 740  TYR A CE2 1 
ATOM   4049 C CZ  . TYR A 1 618  ? 150.454 149.536 114.282 1.00 52.00  ? 740  TYR A CZ  1 
ATOM   4050 O OH  . TYR A 1 618  ? 150.492 150.694 113.565 1.00 57.59  ? 740  TYR A OH  1 
ATOM   4051 N N   . ASP A 1 619  ? 149.602 142.739 117.404 1.00 64.43  ? 741  ASP A N   1 
ATOM   4052 C CA  . ASP A 1 619  ? 150.068 141.571 118.146 1.00 62.85  ? 741  ASP A CA  1 
ATOM   4053 C C   . ASP A 1 619  ? 150.021 140.324 117.273 1.00 67.49  ? 741  ASP A C   1 
ATOM   4054 O O   . ASP A 1 619  ? 150.667 139.318 117.581 1.00 75.04  ? 741  ASP A O   1 
ATOM   4055 C CB  . ASP A 1 619  ? 149.266 141.404 119.445 1.00 65.90  ? 741  ASP A CB  1 
ATOM   4056 C CG  . ASP A 1 619  ? 147.802 141.049 119.219 1.00 79.43  ? 741  ASP A CG  1 
ATOM   4057 O OD1 . ASP A 1 619  ? 146.952 141.952 119.295 1.00 75.78  ? 741  ASP A OD1 1 
ATOM   4058 O OD2 . ASP A 1 619  ? 147.477 139.854 119.077 1.00 89.59  ? 741  ASP A OD2 1 
ATOM   4059 N N   . GLY A 1 620  ? 149.267 140.378 116.179 1.00 64.28  ? 742  GLY A N   1 
ATOM   4060 C CA  . GLY A 1 620  ? 149.157 139.281 115.242 1.00 67.73  ? 742  GLY A CA  1 
ATOM   4061 C C   . GLY A 1 620  ? 148.037 138.311 115.534 1.00 78.77  ? 742  GLY A C   1 
ATOM   4062 O O   . GLY A 1 620  ? 147.856 137.357 114.767 1.00 86.67  ? 742  GLY A O   1 
ATOM   4063 N N   . GLY A 1 621  ? 147.281 138.514 116.615 1.00 71.71  ? 743  GLY A N   1 
ATOM   4064 C CA  . GLY A 1 621  ? 146.259 137.548 116.981 1.00 72.84  ? 743  GLY A CA  1 
ATOM   4065 C C   . GLY A 1 621  ? 144.992 137.677 116.161 1.00 75.37  ? 743  GLY A C   1 
ATOM   4066 O O   . GLY A 1 621  ? 144.325 136.680 115.874 1.00 83.51  ? 743  GLY A O   1 
ATOM   4067 N N   . PHE A 1 622  ? 144.640 138.896 115.776 1.00 68.11  ? 744  PHE A N   1 
ATOM   4068 C CA  . PHE A 1 622  ? 143.465 139.140 114.952 1.00 68.60  ? 744  PHE A CA  1 
ATOM   4069 C C   . PHE A 1 622  ? 143.911 139.178 113.498 1.00 72.19  ? 744  PHE A C   1 
ATOM   4070 O O   . PHE A 1 622  ? 144.625 140.094 113.089 1.00 74.72  ? 744  PHE A O   1 
ATOM   4071 C CB  . PHE A 1 622  ? 142.774 140.444 115.350 1.00 66.00  ? 744  PHE A CB  1 
ATOM   4072 C CG  . PHE A 1 622  ? 141.777 140.941 114.339 1.00 63.15  ? 744  PHE A CG  1 
ATOM   4073 C CD1 . PHE A 1 622  ? 140.575 140.259 114.146 1.00 67.17  ? 744  PHE A CD1 1 
ATOM   4074 C CD2 . PHE A 1 622  ? 142.028 142.101 113.598 1.00 60.14  ? 744  PHE A CD2 1 
ATOM   4075 C CE1 . PHE A 1 622  ? 139.639 140.710 113.216 1.00 64.22  ? 744  PHE A CE1 1 
ATOM   4076 C CE2 . PHE A 1 622  ? 141.104 142.562 112.663 1.00 64.82  ? 744  PHE A CE2 1 
ATOM   4077 C CZ  . PHE A 1 622  ? 139.907 141.863 112.476 1.00 67.48  ? 744  PHE A CZ  1 
ATOM   4078 N N   . LYS A 1 623  ? 143.496 138.184 112.720 1.00 72.16  ? 745  LYS A N   1 
ATOM   4079 C CA  . LYS A 1 623  ? 143.676 138.197 111.276 1.00 66.22  ? 745  LYS A CA  1 
ATOM   4080 C C   . LYS A 1 623  ? 142.307 138.022 110.635 1.00 68.92  ? 745  LYS A C   1 
ATOM   4081 O O   . LYS A 1 623  ? 141.428 137.368 111.207 1.00 80.28  ? 745  LYS A O   1 
ATOM   4082 C CB  . LYS A 1 623  ? 144.669 137.122 110.822 1.00 66.71  ? 745  LYS A CB  1 
ATOM   4083 C CG  . LYS A 1 623  ? 144.316 135.693 111.187 1.00 80.26  ? 745  LYS A CG  1 
ATOM   4084 C CD  . LYS A 1 623  ? 145.424 134.732 110.803 1.00 86.14  ? 745  LYS A CD  1 
ATOM   4085 C CE  . LYS A 1 623  ? 146.538 134.750 111.834 1.00 90.83  ? 745  LYS A CE  1 
ATOM   4086 N NZ  . LYS A 1 623  ? 147.506 133.639 111.626 1.00 94.45  ? 745  LYS A NZ  1 
ATOM   4087 N N   . HIS A 1 624  ? 142.109 138.647 109.478 1.00 64.42  ? 746  HIS A N   1 
ATOM   4088 C CA  . HIS A 1 624  ? 140.814 138.655 108.820 1.00 73.48  ? 746  HIS A CA  1 
ATOM   4089 C C   . HIS A 1 624  ? 141.014 138.849 107.321 1.00 78.58  ? 746  HIS A C   1 
ATOM   4090 O O   . HIS A 1 624  ? 141.573 139.875 106.905 1.00 80.91  ? 746  HIS A O   1 
ATOM   4091 C CB  . HIS A 1 624  ? 139.921 139.767 109.384 1.00 74.17  ? 746  HIS A CB  1 
ATOM   4092 C CG  . HIS A 1 624  ? 138.555 139.809 108.776 1.00 86.88  ? 746  HIS A CG  1 
ATOM   4093 N ND1 . HIS A 1 624  ? 137.910 140.991 108.480 1.00 89.84  ? 746  HIS A ND1 1 
ATOM   4094 C CD2 . HIS A 1 624  ? 137.711 138.817 108.410 1.00 89.73  ? 746  HIS A CD2 1 
ATOM   4095 C CE1 . HIS A 1 624  ? 136.727 140.724 107.955 1.00 92.36  ? 746  HIS A CE1 1 
ATOM   4096 N NE2 . HIS A 1 624  ? 136.582 139.412 107.901 1.00 92.85  ? 746  HIS A NE2 1 
ATOM   4097 N N   . PRO A 1 625  ? 140.605 137.895 106.486 1.00 78.97  ? 747  PRO A N   1 
ATOM   4098 C CA  . PRO A 1 625  ? 140.682 138.111 105.039 1.00 82.12  ? 747  PRO A CA  1 
ATOM   4099 C C   . PRO A 1 625  ? 139.604 139.063 104.551 1.00 85.59  ? 747  PRO A C   1 
ATOM   4100 O O   . PRO A 1 625  ? 138.505 139.140 105.106 1.00 91.47  ? 747  PRO A O   1 
ATOM   4101 C CB  . PRO A 1 625  ? 140.485 136.705 104.458 1.00 86.74  ? 747  PRO A CB  1 
ATOM   4102 C CG  . PRO A 1 625  ? 140.747 135.774 105.598 1.00 84.33  ? 747  PRO A CG  1 
ATOM   4103 C CD  . PRO A 1 625  ? 140.252 136.503 106.800 1.00 76.87  ? 747  PRO A CD  1 
ATOM   4104 N N   . LEU A 1 626  ? 139.937 139.794 103.496 1.00 86.61  ? 748  LEU A N   1 
ATOM   4105 C CA  . LEU A 1 626  ? 139.075 140.762 102.840 1.00 96.20  ? 748  LEU A CA  1 
ATOM   4106 C C   . LEU A 1 626  ? 139.035 140.435 101.355 1.00 103.76 ? 748  LEU A C   1 
ATOM   4107 O O   . LEU A 1 626  ? 139.977 139.820 100.842 1.00 100.50 ? 748  LEU A O   1 
ATOM   4108 C CB  . LEU A 1 626  ? 139.602 142.191 103.062 1.00 93.09  ? 748  LEU A CB  1 
ATOM   4109 C CG  . LEU A 1 626  ? 139.437 142.740 104.479 1.00 93.49  ? 748  LEU A CG  1 
ATOM   4110 C CD1 . LEU A 1 626  ? 140.195 144.043 104.648 1.00 83.19  ? 748  LEU A CD1 1 
ATOM   4111 C CD2 . LEU A 1 626  ? 137.967 142.931 104.803 1.00 98.44  ? 748  LEU A CD2 1 
ATOM   4112 N N   . PRO A 1 627  ? 137.953 140.779 100.649 1.00 109.32 ? 749  PRO A N   1 
ATOM   4113 C CA  . PRO A 1 627  ? 137.910 140.509 99.200  1.00 112.02 ? 749  PRO A CA  1 
ATOM   4114 C C   . PRO A 1 627  ? 138.801 141.455 98.405  1.00 109.54 ? 749  PRO A C   1 
ATOM   4115 O O   . PRO A 1 627  ? 138.555 142.661 98.338  1.00 105.18 ? 749  PRO A O   1 
ATOM   4116 C CB  . PRO A 1 627  ? 136.428 140.697 98.845  1.00 110.93 ? 749  PRO A CB  1 
ATOM   4117 C CG  . PRO A 1 627  ? 135.856 141.504 99.958  1.00 104.75 ? 749  PRO A CG  1 
ATOM   4118 C CD  . PRO A 1 627  ? 136.600 141.064 101.171 1.00 102.17 ? 749  PRO A CD  1 
ATOM   4119 N N   . LEU A 1 628  ? 139.851 140.896 97.812  1.00 107.35 ? 750  LEU A N   1 
ATOM   4120 C CA  . LEU A 1 628  ? 140.666 141.606 96.837  1.00 109.30 ? 750  LEU A CA  1 
ATOM   4121 C C   . LEU A 1 628  ? 140.020 141.513 95.457  1.00 119.17 ? 750  LEU A C   1 
ATOM   4122 O O   . LEU A 1 628  ? 139.525 140.445 95.080  1.00 120.44 ? 750  LEU A O   1 
ATOM   4123 C CB  . LEU A 1 628  ? 142.076 141.027 96.783  1.00 104.23 ? 750  LEU A CB  1 
ATOM   4124 C CG  . LEU A 1 628  ? 143.165 141.861 96.105  1.00 103.88 ? 750  LEU A CG  1 
ATOM   4125 C CD1 . LEU A 1 628  ? 143.525 143.071 96.941  1.00 98.25  ? 750  LEU A CD1 1 
ATOM   4126 C CD2 . LEU A 1 628  ? 144.393 141.007 95.850  1.00 102.82 ? 750  LEU A CD2 1 
ATOM   4127 N N   . PRO A 1 629  ? 139.967 142.609 94.699  1.00 122.11 ? 751  PRO A N   1 
ATOM   4128 C CA  . PRO A 1 629  ? 139.390 142.556 93.347  1.00 122.94 ? 751  PRO A CA  1 
ATOM   4129 C C   . PRO A 1 629  ? 140.331 141.869 92.374  1.00 130.73 ? 751  PRO A C   1 
ATOM   4130 O O   . PRO A 1 629  ? 141.546 142.119 92.402  1.00 130.34 ? 751  PRO A O   1 
ATOM   4131 C CB  . PRO A 1 629  ? 139.202 144.037 92.986  1.00 116.42 ? 751  PRO A CB  1 
ATOM   4132 C CG  . PRO A 1 629  ? 139.208 144.742 94.290  1.00 114.14 ? 751  PRO A CG  1 
ATOM   4133 C CD  . PRO A 1 629  ? 140.174 144.002 95.131  1.00 119.54 ? 751  PRO A CD  1 
ATOM   4134 N N   . PRO A 1 630  ? 139.821 140.991 91.506  1.00 133.90 ? 752  PRO A N   1 
ATOM   4135 C CA  . PRO A 1 630  ? 140.712 140.214 90.636  1.00 135.72 ? 752  PRO A CA  1 
ATOM   4136 C C   . PRO A 1 630  ? 141.166 141.022 89.434  1.00 135.30 ? 752  PRO A C   1 
ATOM   4137 O O   . PRO A 1 630  ? 140.402 141.840 88.897  1.00 130.28 ? 752  PRO A O   1 
ATOM   4138 C CB  . PRO A 1 630  ? 139.845 139.019 90.216  1.00 135.73 ? 752  PRO A CB  1 
ATOM   4139 C CG  . PRO A 1 630  ? 138.448 139.500 90.315  1.00 133.10 ? 752  PRO A CG  1 
ATOM   4140 C CD  . PRO A 1 630  ? 138.404 140.605 91.330  1.00 130.52 ? 752  PRO A CD  1 
ATOM   4141 N N   . PRO A 1 631  ? 142.420 140.839 88.983  1.00 136.69 ? 753  PRO A N   1 
ATOM   4142 C CA  . PRO A 1 631  ? 142.863 141.529 87.770  1.00 136.51 ? 753  PRO A CA  1 
ATOM   4143 C C   . PRO A 1 631  ? 142.586 140.717 86.509  1.00 135.92 ? 753  PRO A C   1 
ATOM   4144 O O   . PRO A 1 631  ? 142.315 141.305 85.462  1.00 132.99 ? 753  PRO A O   1 
ATOM   4145 C CB  . PRO A 1 631  ? 144.366 141.688 87.996  1.00 134.24 ? 753  PRO A CB  1 
ATOM   4146 C CG  . PRO A 1 631  ? 144.740 140.506 88.826  1.00 131.04 ? 753  PRO A CG  1 
ATOM   4147 C CD  . PRO A 1 631  ? 143.520 140.083 89.611  1.00 133.10 ? 753  PRO A CD  1 
ATOM   4148 N N   . HIS A 1 643  ? 148.185 140.151 88.355  1.00 135.04 ? 765  HIS A N   1 
ATOM   4149 C CA  . HIS A 1 643  ? 148.498 140.182 89.779  1.00 135.73 ? 765  HIS A CA  1 
ATOM   4150 C C   . HIS A 1 643  ? 148.829 141.592 90.252  1.00 132.77 ? 765  HIS A C   1 
ATOM   4151 O O   . HIS A 1 643  ? 149.489 142.355 89.548  1.00 132.74 ? 765  HIS A O   1 
ATOM   4152 C CB  . HIS A 1 643  ? 149.670 139.251 90.093  1.00 138.06 ? 765  HIS A CB  1 
ATOM   4153 C CG  . HIS A 1 643  ? 149.380 137.804 89.844  1.00 149.34 ? 765  HIS A CG  1 
ATOM   4154 N ND1 . HIS A 1 643  ? 148.593 137.048 90.685  1.00 150.51 ? 765  HIS A ND1 1 
ATOM   4155 C CD2 . HIS A 1 643  ? 149.776 136.974 88.852  1.00 150.47 ? 765  HIS A CD2 1 
ATOM   4156 C CE1 . HIS A 1 643  ? 148.514 135.814 90.219  1.00 150.44 ? 765  HIS A CE1 1 
ATOM   4157 N NE2 . HIS A 1 643  ? 149.224 135.743 89.108  1.00 151.63 ? 765  HIS A NE2 1 
ATOM   4158 N N   . TRP A 1 644  ? 148.366 141.932 91.449  1.00 128.76 ? 766  TRP A N   1 
ATOM   4159 C CA  . TRP A 1 644  ? 148.738 143.181 92.089  1.00 120.80 ? 766  TRP A CA  1 
ATOM   4160 C C   . TRP A 1 644  ? 150.015 142.979 92.892  1.00 119.71 ? 766  TRP A C   1 
ATOM   4161 O O   . TRP A 1 644  ? 150.181 141.971 93.582  1.00 123.04 ? 766  TRP A O   1 
ATOM   4162 C CB  . TRP A 1 644  ? 147.626 143.680 93.011  1.00 118.83 ? 766  TRP A CB  1 
ATOM   4163 C CG  . TRP A 1 644  ? 146.250 143.603 92.428  1.00 122.72 ? 766  TRP A CG  1 
ATOM   4164 C CD1 . TRP A 1 644  ? 145.261 142.735 92.782  1.00 121.03 ? 766  TRP A CD1 1 
ATOM   4165 C CD2 . TRP A 1 644  ? 145.707 144.427 91.392  1.00 121.21 ? 766  TRP A CD2 1 
ATOM   4166 N NE1 . TRP A 1 644  ? 144.135 142.964 92.032  1.00 119.26 ? 766  TRP A NE1 1 
ATOM   4167 C CE2 . TRP A 1 644  ? 144.383 143.998 91.169  1.00 119.94 ? 766  TRP A CE2 1 
ATOM   4168 C CE3 . TRP A 1 644  ? 146.212 145.484 90.628  1.00 117.01 ? 766  TRP A CE3 1 
ATOM   4169 C CZ2 . TRP A 1 644  ? 143.557 144.591 90.214  1.00 118.87 ? 766  TRP A CZ2 1 
ATOM   4170 C CZ3 . TRP A 1 644  ? 145.392 146.074 89.679  1.00 118.59 ? 766  TRP A CZ3 1 
ATOM   4171 C CH2 . TRP A 1 644  ? 144.079 145.624 89.480  1.00 118.96 ? 766  TRP A CH2 1 
ATOM   4172 N N   . GLN A 1 645  ? 150.932 143.939 92.784  1.00 113.34 ? 767  GLN A N   1 
ATOM   4173 C CA  . GLN A 1 645  ? 152.172 143.888 93.540  1.00 109.01 ? 767  GLN A CA  1 
ATOM   4174 C C   . GLN A 1 645  ? 152.349 145.045 94.511  1.00 103.33 ? 767  GLN A C   1 
ATOM   4175 O O   . GLN A 1 645  ? 153.357 145.077 95.226  1.00 105.22 ? 767  GLN A O   1 
ATOM   4176 C CB  . GLN A 1 645  ? 153.381 143.823 92.594  1.00 108.61 ? 767  GLN A CB  1 
ATOM   4177 C CG  . GLN A 1 645  ? 153.455 144.938 91.575  1.00 112.15 ? 767  GLN A CG  1 
ATOM   4178 C CD  . GLN A 1 645  ? 154.465 144.643 90.485  1.00 118.22 ? 767  GLN A CD  1 
ATOM   4179 O OE1 . GLN A 1 645  ? 154.101 144.394 89.337  1.00 115.88 ? 767  GLN A OE1 1 
ATOM   4180 N NE2 . GLN A 1 645  ? 155.743 144.656 90.844  1.00 117.89 ? 767  GLN A NE2 1 
ATOM   4181 N N   . SER A 1 646  ? 151.397 145.975 94.573  1.00 97.56  ? 768  SER A N   1 
ATOM   4182 C CA  . SER A 1 646  ? 151.358 147.011 95.594  1.00 90.16  ? 768  SER A CA  1 
ATOM   4183 C C   . SER A 1 646  ? 149.913 147.436 95.787  1.00 90.70  ? 768  SER A C   1 
ATOM   4184 O O   . SER A 1 646  ? 149.042 147.108 94.979  1.00 101.25 ? 768  SER A O   1 
ATOM   4185 C CB  . SER A 1 646  ? 152.210 148.226 95.222  1.00 95.52  ? 768  SER A CB  1 
ATOM   4186 O OG  . SER A 1 646  ? 152.169 149.191 96.256  1.00 100.56 ? 768  SER A OG  1 
ATOM   4187 N N   . PHE A 1 647  ? 149.662 148.160 96.878  1.00 85.84  ? 769  PHE A N   1 
ATOM   4188 C CA  . PHE A 1 647  ? 148.365 148.788 97.088  1.00 84.17  ? 769  PHE A CA  1 
ATOM   4189 C C   . PHE A 1 647  ? 148.549 150.057 97.908  1.00 85.51  ? 769  PHE A C   1 
ATOM   4190 O O   . PHE A 1 647  ? 149.633 150.350 98.416  1.00 93.98  ? 769  PHE A O   1 
ATOM   4191 C CB  . PHE A 1 647  ? 147.349 147.838 97.764  1.00 80.40  ? 769  PHE A CB  1 
ATOM   4192 C CG  . PHE A 1 647  ? 147.514 147.695 99.256  1.00 74.65  ? 769  PHE A CG  1 
ATOM   4193 C CD1 . PHE A 1 647  ? 148.540 146.915 99.784  1.00 68.68  ? 769  PHE A CD1 1 
ATOM   4194 C CD2 . PHE A 1 647  ? 146.598 148.298 100.132 1.00 80.83  ? 769  PHE A CD2 1 
ATOM   4195 C CE1 . PHE A 1 647  ? 148.681 146.774 101.160 1.00 68.57  ? 769  PHE A CE1 1 
ATOM   4196 C CE2 . PHE A 1 647  ? 146.741 148.172 101.504 1.00 82.92  ? 769  PHE A CE2 1 
ATOM   4197 C CZ  . PHE A 1 647  ? 147.776 147.400 102.013 1.00 74.95  ? 769  PHE A CZ  1 
ATOM   4198 N N   . ALA A 1 648  ? 147.458 150.808 98.031  1.00 81.74  ? 770  ALA A N   1 
ATOM   4199 C CA  . ALA A 1 648  ? 147.343 151.883 99.004  1.00 83.04  ? 770  ALA A CA  1 
ATOM   4200 C C   . ALA A 1 648  ? 145.908 151.917 99.499  1.00 92.91  ? 770  ALA A C   1 
ATOM   4201 O O   . ALA A 1 648  ? 145.000 151.371 98.867  1.00 98.51  ? 770  ALA A O   1 
ATOM   4202 C CB  . ALA A 1 648  ? 147.745 153.236 98.424  1.00 85.91  ? 770  ALA A CB  1 
ATOM   4203 N N   . LEU A 1 649  ? 145.705 152.567 100.639 1.00 92.22  ? 771  LEU A N   1 
ATOM   4204 C CA  . LEU A 1 649  ? 144.420 152.542 101.332 1.00 90.61  ? 771  LEU A CA  1 
ATOM   4205 C C   . LEU A 1 649  ? 143.956 153.978 101.547 1.00 94.65  ? 771  LEU A C   1 
ATOM   4206 O O   . LEU A 1 649  ? 144.484 154.685 102.409 1.00 97.55  ? 771  LEU A O   1 
ATOM   4207 C CB  . LEU A 1 649  ? 144.541 151.789 102.651 1.00 87.86  ? 771  LEU A CB  1 
ATOM   4208 C CG  . LEU A 1 649  ? 143.276 151.603 103.480 1.00 99.73  ? 771  LEU A CG  1 
ATOM   4209 C CD1 . LEU A 1 649  ? 142.270 150.773 102.711 1.00 102.07 ? 771  LEU A CD1 1 
ATOM   4210 C CD2 . LEU A 1 649  ? 143.607 150.954 104.807 1.00 103.67 ? 771  LEU A CD2 1 
ATOM   4211 N N   . LEU A 1 650  ? 142.972 154.407 100.762 1.00 98.09  ? 772  LEU A N   1 
ATOM   4212 C CA  . LEU A 1 650  ? 142.391 155.737 100.891 1.00 95.45  ? 772  LEU A CA  1 
ATOM   4213 C C   . LEU A 1 650  ? 140.957 155.599 101.388 1.00 101.49 ? 772  LEU A C   1 
ATOM   4214 O O   . LEU A 1 650  ? 140.040 155.363 100.593 1.00 103.70 ? 772  LEU A O   1 
ATOM   4215 C CB  . LEU A 1 650  ? 142.445 156.476 99.555  1.00 94.99  ? 772  LEU A CB  1 
ATOM   4216 C CG  . LEU A 1 650  ? 141.964 157.927 99.498  1.00 94.39  ? 772  LEU A CG  1 
ATOM   4217 C CD1 . LEU A 1 650  ? 142.735 158.786 100.480 1.00 91.45  ? 772  LEU A CD1 1 
ATOM   4218 C CD2 . LEU A 1 650  ? 142.102 158.470 98.089  1.00 92.04  ? 772  LEU A CD2 1 
ATOM   4219 N N   . GLY A 1 651  ? 140.767 155.744 102.698 1.00 99.95  ? 773  GLY A N   1 
ATOM   4220 C CA  . GLY A 1 651  ? 139.463 155.480 103.288 1.00 102.76 ? 773  GLY A CA  1 
ATOM   4221 C C   . GLY A 1 651  ? 139.199 153.988 103.338 1.00 108.84 ? 773  GLY A C   1 
ATOM   4222 O O   . GLY A 1 651  ? 140.063 153.194 103.727 1.00 106.72 ? 773  GLY A O   1 
ATOM   4223 N N   . ARG A 1 652  ? 137.989 153.590 102.948 1.00 113.31 ? 774  ARG A N   1 
ATOM   4224 C CA  . ARG A 1 652  ? 137.697 152.190 102.678 1.00 115.67 ? 774  ARG A CA  1 
ATOM   4225 C C   . ARG A 1 652  ? 138.147 151.757 101.290 1.00 114.18 ? 774  ARG A C   1 
ATOM   4226 O O   . ARG A 1 652  ? 138.227 150.553 101.032 1.00 120.36 ? 774  ARG A O   1 
ATOM   4227 C CB  . ARG A 1 652  ? 136.194 151.905 102.822 1.00 124.96 ? 774  ARG A CB  1 
ATOM   4228 C CG  . ARG A 1 652  ? 135.604 152.118 104.214 1.00 127.20 ? 774  ARG A CG  1 
ATOM   4229 C CD  . ARG A 1 652  ? 136.082 151.086 105.216 1.00 131.68 ? 774  ARG A CD  1 
ATOM   4230 N NE  . ARG A 1 652  ? 135.655 149.739 104.859 1.00 140.79 ? 774  ARG A NE  1 
ATOM   4231 C CZ  . ARG A 1 652  ? 136.178 148.630 105.362 1.00 140.89 ? 774  ARG A CZ  1 
ATOM   4232 N NH1 . ARG A 1 652  ? 137.142 148.669 106.268 1.00 139.62 ? 774  ARG A NH1 1 
ATOM   4233 N NH2 . ARG A 1 652  ? 135.721 147.451 104.949 1.00 134.75 ? 774  ARG A NH2 1 
ATOM   4234 N N   . SER A 1 653  ? 138.440 152.701 100.399 1.00 109.91 ? 775  SER A N   1 
ATOM   4235 C CA  . SER A 1 653  ? 138.777 152.373 99.023  1.00 111.23 ? 775  SER A CA  1 
ATOM   4236 C C   . SER A 1 653  ? 140.229 151.914 98.910  1.00 107.13 ? 775  SER A C   1 
ATOM   4237 O O   . SER A 1 653  ? 141.038 152.087 99.824  1.00 109.13 ? 775  SER A O   1 
ATOM   4238 C CB  . SER A 1 653  ? 138.530 153.573 98.115  1.00 113.47 ? 775  SER A CB  1 
ATOM   4239 O OG  . SER A 1 653  ? 137.163 153.942 98.123  1.00 120.72 ? 775  SER A OG  1 
ATOM   4240 N N   . LEU A 1 654  ? 140.552 151.324 97.762  1.00 103.33 ? 776  LEU A N   1 
ATOM   4241 C CA  . LEU A 1 654  ? 141.826 150.646 97.545  1.00 96.09  ? 776  LEU A CA  1 
ATOM   4242 C C   . LEU A 1 654  ? 142.452 151.179 96.262  1.00 103.98 ? 776  LEU A C   1 
ATOM   4243 O O   . LEU A 1 654  ? 141.890 151.004 95.176  1.00 111.32 ? 776  LEU A O   1 
ATOM   4244 C CB  . LEU A 1 654  ? 141.610 149.138 97.456  1.00 99.98  ? 776  LEU A CB  1 
ATOM   4245 C CG  . LEU A 1 654  ? 142.758 148.199 97.795  1.00 105.74 ? 776  LEU A CG  1 
ATOM   4246 C CD1 . LEU A 1 654  ? 143.022 148.263 99.281  1.00 106.67 ? 776  LEU A CD1 1 
ATOM   4247 C CD2 . LEU A 1 654  ? 142.427 146.782 97.364  1.00 105.18 ? 776  LEU A CD2 1 
ATOM   4248 N N   . LEU A 1 655  ? 143.612 151.821 96.382  1.00 100.93 ? 777  LEU A N   1 
ATOM   4249 C CA  . LEU A 1 655  ? 144.362 152.281 95.217  1.00 98.68  ? 777  LEU A CA  1 
ATOM   4250 C C   . LEU A 1 655  ? 145.237 151.146 94.703  1.00 101.39 ? 777  LEU A C   1 
ATOM   4251 O O   . LEU A 1 655  ? 146.108 150.662 95.427  1.00 103.45 ? 777  LEU A O   1 
ATOM   4252 C CB  . LEU A 1 655  ? 145.223 153.486 95.578  1.00 94.98  ? 777  LEU A CB  1 
ATOM   4253 C CG  . LEU A 1 655  ? 144.548 154.848 95.683  1.00 95.18  ? 777  LEU A CG  1 
ATOM   4254 C CD1 . LEU A 1 655  ? 145.253 155.712 96.708  1.00 94.89  ? 777  LEU A CD1 1 
ATOM   4255 C CD2 . LEU A 1 655  ? 144.530 155.530 94.330  1.00 100.08 ? 777  LEU A CD2 1 
ATOM   4256 N N   . LEU A 1 656  ? 145.023 150.729 93.457  1.00 102.34 ? 778  LEU A N   1 
ATOM   4257 C CA  . LEU A 1 656  ? 145.744 149.593 92.899  1.00 102.41 ? 778  LEU A CA  1 
ATOM   4258 C C   . LEU A 1 656  ? 146.444 150.010 91.610  1.00 106.38 ? 778  LEU A C   1 
ATOM   4259 O O   . LEU A 1 656  ? 145.805 150.600 90.724  1.00 114.51 ? 778  LEU A O   1 
ATOM   4260 C CB  . LEU A 1 656  ? 144.791 148.421 92.636  1.00 109.11 ? 778  LEU A CB  1 
ATOM   4261 C CG  . LEU A 1 656  ? 144.152 147.783 93.871  1.00 109.94 ? 778  LEU A CG  1 
ATOM   4262 C CD1 . LEU A 1 656  ? 142.947 146.941 93.490  1.00 114.40 ? 778  LEU A CD1 1 
ATOM   4263 C CD2 . LEU A 1 656  ? 145.171 146.956 94.634  1.00 106.90 ? 778  LEU A CD2 1 
ATOM   4264 N N   . PRO A 1 657  ? 147.751 149.743 91.465  1.00 107.30 ? 779  PRO A N   1 
ATOM   4265 C CA  . PRO A 1 657  ? 148.437 150.089 90.213  1.00 110.60 ? 779  PRO A CA  1 
ATOM   4266 C C   . PRO A 1 657  ? 148.418 148.976 89.178  1.00 117.52 ? 779  PRO A C   1 
ATOM   4267 O O   . PRO A 1 657  ? 148.203 147.806 89.502  1.00 121.28 ? 779  PRO A O   1 
ATOM   4268 C CB  . PRO A 1 657  ? 149.867 150.367 90.681  1.00 107.41 ? 779  PRO A CB  1 
ATOM   4269 C CG  . PRO A 1 657  ? 150.045 149.417 91.801  1.00 106.01 ? 779  PRO A CG  1 
ATOM   4270 C CD  . PRO A 1 657  ? 148.714 149.360 92.512  1.00 106.03 ? 779  PRO A CD  1 
ATOM   4271 N N   . ASP A 1 658  ? 148.645 149.337 87.924  1.00 124.68 ? 780  ASP A N   1 
ATOM   4272 C CA  . ASP A 1 658  ? 148.853 148.388 86.841  1.00 130.06 ? 780  ASP A CA  1 
ATOM   4273 C C   . ASP A 1 658  ? 150.038 148.853 85.999  1.00 134.75 ? 780  ASP A C   1 
ATOM   4274 O O   . ASP A 1 658  ? 150.791 149.750 86.385  1.00 135.76 ? 780  ASP A O   1 
ATOM   4275 C CB  . ASP A 1 658  ? 147.591 148.233 85.989  1.00 130.45 ? 780  ASP A CB  1 
ATOM   4276 C CG  . ASP A 1 658  ? 146.722 147.083 86.441  1.00 131.80 ? 780  ASP A CG  1 
ATOM   4277 O OD1 . ASP A 1 658  ? 147.280 146.036 86.828  1.00 131.63 ? 780  ASP A OD1 1 
ATOM   4278 O OD2 . ASP A 1 658  ? 145.482 147.224 86.402  1.00 128.80 ? 780  ASP A OD2 1 
ATOM   4279 N N   . SER A 1 659  ? 150.200 148.228 84.836  1.00 138.68 ? 781  SER A N   1 
ATOM   4280 C CA  . SER A 1 659  ? 151.203 148.677 83.882  1.00 143.66 ? 781  SER A CA  1 
ATOM   4281 C C   . SER A 1 659  ? 150.759 149.901 83.093  1.00 142.25 ? 781  SER A C   1 
ATOM   4282 O O   . SER A 1 659  ? 151.609 150.580 82.508  1.00 140.09 ? 781  SER A O   1 
ATOM   4283 C CB  . SER A 1 659  ? 151.542 147.546 82.911  1.00 139.82 ? 781  SER A CB  1 
ATOM   4284 O OG  . SER A 1 659  ? 150.362 146.978 82.373  1.00 133.40 ? 781  SER A OG  1 
ATOM   4285 N N   . GLY A 1 660  ? 149.463 150.201 83.069  1.00 136.53 ? 782  GLY A N   1 
ATOM   4286 C CA  . GLY A 1 660  ? 148.968 151.308 82.279  1.00 133.16 ? 782  GLY A CA  1 
ATOM   4287 C C   . GLY A 1 660  ? 148.037 152.265 82.993  1.00 135.79 ? 782  GLY A C   1 
ATOM   4288 O O   . GLY A 1 660  ? 147.761 153.347 82.466  1.00 137.39 ? 782  GLY A O   1 
ATOM   4289 N N   . GLN A 1 661  ? 147.542 151.894 84.176  1.00 135.12 ? 783  GLN A N   1 
ATOM   4290 C CA  . GLN A 1 661  ? 146.539 152.701 84.858  1.00 130.82 ? 783  GLN A CA  1 
ATOM   4291 C C   . GLN A 1 661  ? 146.583 152.461 86.363  1.00 126.56 ? 783  GLN A C   1 
ATOM   4292 O O   . GLN A 1 661  ? 147.107 151.453 86.841  1.00 126.91 ? 783  GLN A O   1 
ATOM   4293 C CB  . GLN A 1 661  ? 145.134 152.417 84.303  1.00 130.65 ? 783  GLN A CB  1 
ATOM   4294 C CG  . GLN A 1 661  ? 144.619 151.021 84.565  1.00 132.91 ? 783  GLN A CG  1 
ATOM   4295 C CD  . GLN A 1 661  ? 143.110 150.959 84.541  1.00 135.85 ? 783  GLN A CD  1 
ATOM   4296 O OE1 . GLN A 1 661  ? 142.436 151.988 84.534  1.00 132.28 ? 783  GLN A OE1 1 
ATOM   4297 N NE2 . GLN A 1 661  ? 142.568 149.748 84.528  1.00 138.35 ? 783  GLN A NE2 1 
ATOM   4298 N N   . LEU A 1 662  ? 146.034 153.423 87.101  1.00 123.48 ? 784  LEU A N   1 
ATOM   4299 C CA  . LEU A 1 662  ? 145.856 153.348 88.547  1.00 118.22 ? 784  LEU A CA  1 
ATOM   4300 C C   . LEU A 1 662  ? 144.378 153.526 88.859  1.00 116.85 ? 784  LEU A C   1 
ATOM   4301 O O   . LEU A 1 662  ? 143.770 154.506 88.424  1.00 122.21 ? 784  LEU A O   1 
ATOM   4302 C CB  . LEU A 1 662  ? 146.681 154.429 89.251  1.00 115.57 ? 784  LEU A CB  1 
ATOM   4303 C CG  . LEU A 1 662  ? 146.576 154.581 90.770  1.00 111.57 ? 784  LEU A CG  1 
ATOM   4304 C CD1 . LEU A 1 662  ? 147.396 153.538 91.495  1.00 108.71 ? 784  LEU A CD1 1 
ATOM   4305 C CD2 . LEU A 1 662  ? 147.004 155.976 91.187  1.00 113.31 ? 784  LEU A CD2 1 
ATOM   4306 N N   . ILE A 1 663  ? 143.802 152.597 89.618  1.00 109.77 ? 785  ILE A N   1 
ATOM   4307 C CA  . ILE A 1 663  ? 142.358 152.541 89.825  1.00 111.02 ? 785  ILE A CA  1 
ATOM   4308 C C   . ILE A 1 663  ? 142.042 152.723 91.303  1.00 110.70 ? 785  ILE A C   1 
ATOM   4309 O O   . ILE A 1 663  ? 142.835 152.338 92.167  1.00 112.97 ? 785  ILE A O   1 
ATOM   4310 C CB  . ILE A 1 663  ? 141.762 151.224 89.300  1.00 114.38 ? 785  ILE A CB  1 
ATOM   4311 C CG1 . ILE A 1 663  ? 142.644 150.039 89.689  1.00 112.53 ? 785  ILE A CG1 1 
ATOM   4312 C CG2 . ILE A 1 663  ? 141.589 151.283 87.802  1.00 120.33 ? 785  ILE A CG2 1 
ATOM   4313 C CD1 . ILE A 1 663  ? 142.007 148.699 89.437  1.00 117.36 ? 785  ILE A CD1 1 
ATOM   4314 N N   . LEU A 1 664  ? 140.880 153.315 91.582  1.00 110.12 ? 786  LEU A N   1 
ATOM   4315 C CA  . LEU A 1 664  ? 140.365 153.496 92.940  1.00 109.53 ? 786  LEU A CA  1 
ATOM   4316 C C   . LEU A 1 664  ? 139.130 152.619 93.098  1.00 115.64 ? 786  LEU A C   1 
ATOM   4317 O O   . LEU A 1 664  ? 138.034 152.969 92.666  1.00 122.42 ? 786  LEU A O   1 
ATOM   4318 C CB  . LEU A 1 664  ? 140.044 154.961 93.199  1.00 108.70 ? 786  LEU A CB  1 
ATOM   4319 C CG  . LEU A 1 664  ? 139.609 155.340 94.615  1.00 106.23 ? 786  LEU A CG  1 
ATOM   4320 C CD1 . LEU A 1 664  ? 140.769 155.273 95.572  1.00 107.77 ? 786  LEU A CD1 1 
ATOM   4321 C CD2 . LEU A 1 664  ? 138.987 156.723 94.629  1.00 107.03 ? 786  LEU A CD2 1 
ATOM   4322 N N   . VAL A 1 665  ? 139.312 151.454 93.717  1.00 112.62 ? 787  VAL A N   1 
ATOM   4323 C CA  . VAL A 1 665  ? 138.231 150.483 93.851  1.00 115.13 ? 787  VAL A CA  1 
ATOM   4324 C C   . VAL A 1 665  ? 137.855 150.363 95.331  1.00 117.21 ? 787  VAL A C   1 
ATOM   4325 O O   . VAL A 1 665  ? 138.713 150.340 96.212  1.00 120.90 ? 787  VAL A O   1 
ATOM   4326 C CB  . VAL A 1 665  ? 138.671 149.128 93.237  1.00 117.21 ? 787  VAL A CB  1 
ATOM   4327 C CG1 . VAL A 1 665  ? 137.626 148.019 93.356  1.00 127.66 ? 787  VAL A CG1 1 
ATOM   4328 C CG2 . VAL A 1 665  ? 139.058 149.289 91.776  1.00 120.21 ? 787  VAL A CG2 1 
ATOM   4329 N N   . GLU A 1 666  ? 136.548 150.293 95.618  1.00 119.85 ? 788  GLU A N   1 
ATOM   4330 C CA  . GLU A 1 666  ? 136.022 150.342 96.976  1.00 127.51 ? 788  GLU A CA  1 
ATOM   4331 C C   . GLU A 1 666  ? 135.799 148.918 97.531  1.00 137.27 ? 788  GLU A C   1 
ATOM   4332 O O   . GLU A 1 666  ? 134.720 148.596 98.030  1.00 141.11 ? 788  GLU A O   1 
ATOM   4333 C CB  . GLU A 1 666  ? 134.775 151.258 96.963  1.00 130.40 ? 788  GLU A CB  1 
ATOM   4334 C CG  . GLU A 1 666  ? 134.150 151.870 98.281  1.00 140.54 ? 788  GLU A CG  1 
ATOM   4335 C CD  . GLU A 1 666  ? 133.066 151.063 98.983  1.00 148.55 ? 788  GLU A CD  1 
ATOM   4336 O OE1 . GLU A 1 666  ? 132.331 150.320 98.297  1.00 147.81 ? 788  GLU A OE1 1 
ATOM   4337 O OE2 . GLU A 1 666  ? 132.950 151.174 100.221 1.00 144.69 ? 788  GLU A OE2 1 
ATOM   4338 N N   . GLN A 1 667  ? 136.754 148.008 97.265  1.00 137.94 ? 789  GLN A N   1 
ATOM   4339 C CA  . GLN A 1 667  ? 136.999 146.706 97.905  1.00 137.80 ? 789  GLN A CA  1 
ATOM   4340 C C   . GLN A 1 667  ? 135.971 145.602 97.648  1.00 144.89 ? 789  GLN A C   1 
ATOM   4341 O O   . GLN A 1 667  ? 136.165 144.472 98.104  1.00 144.52 ? 789  GLN A O   1 
ATOM   4342 C CB  . GLN A 1 667  ? 137.168 146.863 99.425  1.00 128.85 ? 789  GLN A CB  1 
ATOM   4343 C CG  . GLN A 1 667  ? 138.513 147.396 99.862  1.00 124.90 ? 789  GLN A CG  1 
ATOM   4344 C CD  . GLN A 1 667  ? 138.673 147.376 101.366 1.00 126.82 ? 789  GLN A CD  1 
ATOM   4345 O OE1 . GLN A 1 667  ? 137.781 146.936 102.090 1.00 124.53 ? 789  GLN A OE1 1 
ATOM   4346 N NE2 . GLN A 1 667  ? 139.812 147.859 101.848 1.00 123.82 ? 789  GLN A NE2 1 
ATOM   4347 N N   . GLN A 1 668  ? 134.885 145.893 96.934  1.00 146.59 ? 790  GLN A N   1 
ATOM   4348 C CA  . GLN A 1 668  ? 133.894 144.882 96.587  1.00 146.20 ? 790  GLN A CA  1 
ATOM   4349 C C   . GLN A 1 668  ? 133.609 144.947 95.094  1.00 148.73 ? 790  GLN A C   1 
ATOM   4350 O O   . GLN A 1 668  ? 133.135 143.974 94.500  1.00 149.30 ? 790  GLN A O   1 
ATOM   4351 C CB  . GLN A 1 668  ? 132.599 145.070 97.387  1.00 147.22 ? 790  GLN A CB  1 
ATOM   4352 C CG  . GLN A 1 668  ? 132.718 144.801 98.884  1.00 148.51 ? 790  GLN A CG  1 
ATOM   4353 C CD  . GLN A 1 668  ? 131.557 145.363 99.674  1.00 150.51 ? 790  GLN A CD  1 
ATOM   4354 O OE1 . GLN A 1 668  ? 130.566 145.818 99.103  1.00 151.90 ? 790  GLN A OE1 1 
ATOM   4355 N NE2 . GLN A 1 668  ? 131.672 145.337 100.996 1.00 145.90 ? 790  GLN A NE2 1 
ATOM   4356 N N   . GLY A 1 669  ? 133.900 146.094 94.485  1.00 147.38 ? 791  GLY A N   1 
ATOM   4357 C CA  . GLY A 1 669  ? 133.674 146.253 93.067  1.00 146.78 ? 791  GLY A CA  1 
ATOM   4358 C C   . GLY A 1 669  ? 134.745 145.583 92.229  1.00 151.17 ? 791  GLY A C   1 
ATOM   4359 O O   . GLY A 1 669  ? 135.774 145.119 92.720  1.00 149.57 ? 791  GLY A O   1 
ATOM   4360 N N   . GLN A 1 670  ? 134.485 145.535 90.927  1.00 152.68 ? 792  GLN A N   1 
ATOM   4361 C CA  . GLN A 1 670  ? 135.397 144.895 89.996  1.00 153.17 ? 792  GLN A CA  1 
ATOM   4362 C C   . GLN A 1 670  ? 136.445 145.885 89.500  1.00 149.68 ? 792  GLN A C   1 
ATOM   4363 O O   . GLN A 1 670  ? 136.369 147.091 89.745  1.00 147.13 ? 792  GLN A O   1 
ATOM   4364 C CB  . GLN A 1 670  ? 134.625 144.308 88.815  1.00 152.21 ? 792  GLN A CB  1 
ATOM   4365 C CG  . GLN A 1 670  ? 133.635 145.275 88.190  1.00 154.44 ? 792  GLN A CG  1 
ATOM   4366 C CD  . GLN A 1 670  ? 132.982 144.718 86.942  1.00 159.58 ? 792  GLN A CD  1 
ATOM   4367 O OE1 . GLN A 1 670  ? 133.255 143.588 86.537  1.00 161.49 ? 792  GLN A OE1 1 
ATOM   4368 N NE2 . GLN A 1 670  ? 132.112 145.509 86.326  1.00 157.82 ? 792  GLN A NE2 1 
ATOM   4369 N N   . ALA A 1 671  ? 137.439 145.351 88.786  1.00 148.68 ? 793  ALA A N   1 
ATOM   4370 C CA  . ALA A 1 671  ? 138.479 146.201 88.214  1.00 147.09 ? 793  ALA A CA  1 
ATOM   4371 C C   . ALA A 1 671  ? 138.017 146.846 86.914  1.00 151.31 ? 793  ALA A C   1 
ATOM   4372 O O   . ALA A 1 671  ? 138.612 147.826 86.452  1.00 146.02 ? 793  ALA A O   1 
ATOM   4373 C CB  . ALA A 1 671  ? 139.755 145.391 87.989  1.00 134.86 ? 793  ALA A CB  1 
ATOM   4374 N N   . ALA A 1 672  ? 136.959 146.303 86.303  1.00 153.78 ? 794  ALA A N   1 
ATOM   4375 C CA  . ALA A 1 672  ? 136.410 146.889 85.086  1.00 150.90 ? 794  ALA A CA  1 
ATOM   4376 C C   . ALA A 1 672  ? 135.615 148.158 85.360  1.00 150.91 ? 794  ALA A C   1 
ATOM   4377 O O   . ALA A 1 672  ? 135.461 148.986 84.455  1.00 148.60 ? 794  ALA A O   1 
ATOM   4378 C CB  . ALA A 1 672  ? 135.531 145.870 84.361  1.00 145.66 ? 794  ALA A CB  1 
ATOM   4379 N N   . SER A 1 673  ? 135.104 148.332 86.580  1.00 151.64 ? 795  SER A N   1 
ATOM   4380 C CA  . SER A 1 673  ? 134.368 149.532 86.972  1.00 149.42 ? 795  SER A CA  1 
ATOM   4381 C C   . SER A 1 673  ? 134.973 150.126 88.242  1.00 145.58 ? 795  SER A C   1 
ATOM   4382 O O   . SER A 1 673  ? 134.511 149.833 89.355  1.00 140.61 ? 795  SER A O   1 
ATOM   4383 C CB  . SER A 1 673  ? 132.887 149.222 87.176  1.00 148.01 ? 795  SER A CB  1 
ATOM   4384 O OG  . SER A 1 673  ? 132.165 150.389 87.524  1.00 143.06 ? 795  SER A OG  1 
ATOM   4385 N N   . PRO A 1 674  ? 136.008 150.962 88.120  1.00 141.78 ? 796  PRO A N   1 
ATOM   4386 C CA  . PRO A 1 674  ? 136.527 151.654 89.305  1.00 134.03 ? 796  PRO A CA  1 
ATOM   4387 C C   . PRO A 1 674  ? 135.751 152.930 89.584  1.00 132.18 ? 796  PRO A C   1 
ATOM   4388 O O   . PRO A 1 674  ? 134.972 153.403 88.752  1.00 136.39 ? 796  PRO A O   1 
ATOM   4389 C CB  . PRO A 1 674  ? 137.976 151.963 88.919  1.00 129.53 ? 796  PRO A CB  1 
ATOM   4390 C CG  . PRO A 1 674  ? 137.902 152.182 87.455  1.00 131.24 ? 796  PRO A CG  1 
ATOM   4391 C CD  . PRO A 1 674  ? 136.833 151.256 86.929  1.00 138.23 ? 796  PRO A CD  1 
ATOM   4392 N N   . SER A 1 675  ? 135.963 153.486 90.779  1.00 124.68 ? 797  SER A N   1 
ATOM   4393 C CA  . SER A 1 675  ? 135.372 154.783 91.094  1.00 124.91 ? 797  SER A CA  1 
ATOM   4394 C C   . SER A 1 675  ? 136.118 155.909 90.390  1.00 126.03 ? 797  SER A C   1 
ATOM   4395 O O   . SER A 1 675  ? 135.513 156.909 89.987  1.00 126.35 ? 797  SER A O   1 
ATOM   4396 C CB  . SER A 1 675  ? 135.358 155.007 92.604  1.00 117.98 ? 797  SER A CB  1 
ATOM   4397 O OG  . SER A 1 675  ? 134.805 156.271 92.926  1.00 120.87 ? 797  SER A OG  1 
ATOM   4398 N N   . ALA A 1 676  ? 137.432 155.761 90.231  1.00 122.71 ? 798  ALA A N   1 
ATOM   4399 C CA  . ALA A 1 676  ? 138.248 156.723 89.506  1.00 121.03 ? 798  ALA A CA  1 
ATOM   4400 C C   . ALA A 1 676  ? 139.415 155.994 88.859  1.00 118.05 ? 798  ALA A C   1 
ATOM   4401 O O   . ALA A 1 676  ? 139.837 154.934 89.326  1.00 117.17 ? 798  ALA A O   1 
ATOM   4402 C CB  . ALA A 1 676  ? 138.765 157.837 90.421  1.00 116.28 ? 798  ALA A CB  1 
ATOM   4403 N N   . SER A 1 677  ? 139.931 156.569 87.777  1.00 118.71 ? 799  SER A N   1 
ATOM   4404 C CA  . SER A 1 677  ? 141.055 155.992 87.057  1.00 119.99 ? 799  SER A CA  1 
ATOM   4405 C C   . SER A 1 677  ? 142.018 157.089 86.626  1.00 124.43 ? 799  SER A C   1 
ATOM   4406 O O   . SER A 1 677  ? 141.594 158.178 86.229  1.00 125.99 ? 799  SER A O   1 
ATOM   4407 C CB  . SER A 1 677  ? 140.589 155.202 85.833  1.00 119.62 ? 799  SER A CB  1 
ATOM   4408 O OG  . SER A 1 677  ? 141.668 154.963 84.947  1.00 119.86 ? 799  SER A OG  1 
ATOM   4409 N N   . TRP A 1 678  ? 143.313 156.792 86.708  1.00 122.61 ? 800  TRP A N   1 
ATOM   4410 C CA  . TRP A 1 678  ? 144.363 157.708 86.270  1.00 122.48 ? 800  TRP A CA  1 
ATOM   4411 C C   . TRP A 1 678  ? 145.305 156.939 85.353  1.00 126.60 ? 800  TRP A C   1 
ATOM   4412 O O   . TRP A 1 678  ? 145.863 155.906 85.776  1.00 126.20 ? 800  TRP A O   1 
ATOM   4413 C CB  . TRP A 1 678  ? 145.116 158.300 87.460  1.00 118.11 ? 800  TRP A CB  1 
ATOM   4414 C CG  . TRP A 1 678  ? 144.241 159.049 88.413  1.00 117.23 ? 800  TRP A CG  1 
ATOM   4415 C CD1 . TRP A 1 678  ? 143.887 160.362 88.338  1.00 115.54 ? 800  TRP A CD1 1 
ATOM   4416 C CD2 . TRP A 1 678  ? 143.613 158.529 89.588  1.00 117.21 ? 800  TRP A CD2 1 
ATOM   4417 N NE1 . TRP A 1 678  ? 143.076 160.695 89.394  1.00 121.50 ? 800  TRP A NE1 1 
ATOM   4418 C CE2 . TRP A 1 678  ? 142.891 159.587 90.178  1.00 120.42 ? 800  TRP A CE2 1 
ATOM   4419 C CE3 . TRP A 1 678  ? 143.590 157.271 90.202  1.00 114.23 ? 800  TRP A CE3 1 
ATOM   4420 C CZ2 . TRP A 1 678  ? 142.152 159.426 91.350  1.00 115.01 ? 800  TRP A CZ2 1 
ATOM   4421 C CZ3 . TRP A 1 678  ? 142.856 157.111 91.368  1.00 114.01 ? 800  TRP A CZ3 1 
ATOM   4422 C CH2 . TRP A 1 678  ? 142.148 158.185 91.929  1.00 111.20 ? 800  TRP A CH2 1 
ATOM   4423 N N   . PRO A 1 679  ? 145.517 157.381 84.112  1.00 129.71 ? 801  PRO A N   1 
ATOM   4424 C CA  . PRO A 1 679  ? 146.339 156.600 83.181  1.00 128.66 ? 801  PRO A CA  1 
ATOM   4425 C C   . PRO A 1 679  ? 147.830 156.783 83.423  1.00 128.93 ? 801  PRO A C   1 
ATOM   4426 O O   . PRO A 1 679  ? 148.288 157.825 83.894  1.00 128.59 ? 801  PRO A O   1 
ATOM   4427 C CB  . PRO A 1 679  ? 145.936 157.150 81.805  1.00 126.12 ? 801  PRO A CB  1 
ATOM   4428 C CG  . PRO A 1 679  ? 144.693 157.975 82.053  1.00 126.92 ? 801  PRO A CG  1 
ATOM   4429 C CD  . PRO A 1 679  ? 144.881 158.516 83.426  1.00 127.79 ? 801  PRO A CD  1 
ATOM   4430 N N   . LEU A 1 680  ? 148.588 155.741 83.083  1.00 132.59 ? 802  LEU A N   1 
ATOM   4431 C CA  . LEU A 1 680  ? 150.039 155.730 83.217  1.00 135.79 ? 802  LEU A CA  1 
ATOM   4432 C C   . LEU A 1 680  ? 150.663 155.433 81.864  1.00 142.55 ? 802  LEU A C   1 
ATOM   4433 O O   . LEU A 1 680  ? 150.117 154.645 81.086  1.00 145.80 ? 802  LEU A O   1 
ATOM   4434 C CB  . LEU A 1 680  ? 150.493 154.688 84.240  1.00 136.44 ? 802  LEU A CB  1 
ATOM   4435 C CG  . LEU A 1 680  ? 150.105 155.036 85.671  1.00 135.01 ? 802  LEU A CG  1 
ATOM   4436 C CD1 . LEU A 1 680  ? 150.132 153.815 86.574  1.00 130.65 ? 802  LEU A CD1 1 
ATOM   4437 C CD2 . LEU A 1 680  ? 151.036 156.107 86.158  1.00 134.77 ? 802  LEU A CD2 1 
ATOM   4438 N N   . LYS A 1 681  ? 151.803 156.063 81.585  1.00 145.20 ? 803  LYS A N   1 
ATOM   4439 C CA  . LYS A 1 681  ? 152.464 155.909 80.297  1.00 152.04 ? 803  LYS A CA  1 
ATOM   4440 C C   . LYS A 1 681  ? 153.877 155.356 80.377  1.00 152.37 ? 803  LYS A C   1 
ATOM   4441 O O   . LYS A 1 681  ? 154.184 154.390 79.678  1.00 151.09 ? 803  LYS A O   1 
ATOM   4442 C CB  . LYS A 1 681  ? 152.511 157.254 79.563  1.00 150.82 ? 803  LYS A CB  1 
ATOM   4443 C CG  . LYS A 1 681  ? 152.639 157.130 78.058  1.00 150.21 ? 803  LYS A CG  1 
ATOM   4444 C CD  . LYS A 1 681  ? 152.473 158.480 77.389  1.00 155.01 ? 803  LYS A CD  1 
ATOM   4445 C CE  . LYS A 1 681  ? 152.475 158.351 75.877  1.00 158.24 ? 803  LYS A CE  1 
ATOM   4446 N NZ  . LYS A 1 681  ? 152.250 159.665 75.215  1.00 157.79 ? 803  LYS A NZ  1 
ATOM   4447 N N   . ASN A 1 682  ? 154.743 155.932 81.211  1.00 149.98 ? 804  ASN A N   1 
ATOM   4448 C CA  . ASN A 1 682  ? 156.155 155.577 81.225  1.00 150.36 ? 804  ASN A CA  1 
ATOM   4449 C C   . ASN A 1 682  ? 156.521 154.717 82.424  1.00 147.45 ? 804  ASN A C   1 
ATOM   4450 O O   . ASN A 1 682  ? 157.692 154.664 82.813  1.00 147.58 ? 804  ASN A O   1 
ATOM   4451 C CB  . ASN A 1 682  ? 157.016 156.838 81.198  1.00 154.20 ? 804  ASN A CB  1 
ATOM   4452 C CG  . ASN A 1 682  ? 156.953 157.545 79.868  1.00 155.55 ? 804  ASN A CG  1 
ATOM   4453 O OD1 . ASN A 1 682  ? 156.973 156.910 78.815  1.00 155.76 ? 804  ASN A OD1 1 
ATOM   4454 N ND2 . ASN A 1 682  ? 156.861 158.867 79.907  1.00 153.93 ? 804  ASN A ND2 1 
ATOM   4455 N N   . LEU A 1 683  ? 155.542 154.039 83.015  1.00 147.96 ? 805  LEU A N   1 
ATOM   4456 C CA  . LEU A 1 683  ? 155.768 153.169 84.166  1.00 145.96 ? 805  LEU A CA  1 
ATOM   4457 C C   . LEU A 1 683  ? 155.204 151.792 83.838  1.00 144.10 ? 805  LEU A C   1 
ATOM   4458 O O   . LEU A 1 683  ? 154.021 151.525 84.105  1.00 140.87 ? 805  LEU A O   1 
ATOM   4459 C CB  . LEU A 1 683  ? 155.125 153.754 85.420  1.00 142.91 ? 805  LEU A CB  1 
ATOM   4460 C CG  . LEU A 1 683  ? 155.765 153.372 86.752  1.00 136.57 ? 805  LEU A CG  1 
ATOM   4461 C CD1 . LEU A 1 683  ? 157.176 153.937 86.883  1.00 134.79 ? 805  LEU A CD1 1 
ATOM   4462 C CD2 . LEU A 1 683  ? 154.896 153.815 87.906  1.00 133.65 ? 805  LEU A CD2 1 
ATOM   4463 N N   . PRO A 1 684  ? 155.998 150.903 83.220  1.00 144.11 ? 806  PRO A N   1 
ATOM   4464 C CA  . PRO A 1 684  ? 155.517 149.524 83.016  1.00 142.34 ? 806  PRO A CA  1 
ATOM   4465 C C   . PRO A 1 684  ? 155.444 148.707 84.295  1.00 140.09 ? 806  PRO A C   1 
ATOM   4466 O O   . PRO A 1 684  ? 154.567 147.846 84.423  1.00 135.67 ? 806  PRO A O   1 
ATOM   4467 C CB  . PRO A 1 684  ? 156.529 148.940 82.019  1.00 137.40 ? 806  PRO A CB  1 
ATOM   4468 C CG  . PRO A 1 684  ? 157.749 149.766 82.168  1.00 137.47 ? 806  PRO A CG  1 
ATOM   4469 C CD  . PRO A 1 684  ? 157.300 151.136 82.565  1.00 139.78 ? 806  PRO A CD  1 
ATOM   4470 N N   . ASP A 1 685  ? 156.358 148.929 85.233  1.00 139.52 ? 807  ASP A N   1 
ATOM   4471 C CA  . ASP A 1 685  ? 156.373 148.220 86.507  1.00 136.94 ? 807  ASP A CA  1 
ATOM   4472 C C   . ASP A 1 685  ? 156.285 149.191 87.688  1.00 132.90 ? 807  ASP A C   1 
ATOM   4473 O O   . ASP A 1 685  ? 156.842 150.290 87.647  1.00 138.59 ? 807  ASP A O   1 
ATOM   4474 C CB  . ASP A 1 685  ? 157.569 147.259 86.531  1.00 137.27 ? 807  ASP A CB  1 
ATOM   4475 C CG  . ASP A 1 685  ? 158.945 147.928 86.417  1.00 137.31 ? 807  ASP A CG  1 
ATOM   4476 O OD1 . ASP A 1 685  ? 159.124 149.152 86.277  1.00 135.86 ? 807  ASP A OD1 1 
ATOM   4477 O OD2 . ASP A 1 685  ? 159.916 147.152 86.359  1.00 133.89 ? 807  ASP A OD2 1 
ATOM   4478 N N   . CYS A 1 686  ? 155.502 148.823 88.701  1.00 121.64 ? 808  CYS A N   1 
ATOM   4479 C CA  . CYS A 1 686  ? 155.189 149.711 89.820  1.00 116.52 ? 808  CYS A CA  1 
ATOM   4480 C C   . CYS A 1 686  ? 155.019 148.881 91.084  1.00 109.82 ? 808  CYS A C   1 
ATOM   4481 O O   . CYS A 1 686  ? 153.934 148.348 91.337  1.00 113.87 ? 808  CYS A O   1 
ATOM   4482 C CB  . CYS A 1 686  ? 153.927 150.522 89.527  1.00 119.12 ? 808  CYS A CB  1 
ATOM   4483 S SG  . CYS A 1 686  ? 153.472 151.724 90.798  1.00 131.60 ? 808  CYS A SG  1 
ATOM   4484 N N   . TRP A 1 687  ? 156.080 148.790 91.883  1.00 100.15 ? 809  TRP A N   1 
ATOM   4485 C CA  . TRP A 1 687  ? 156.114 147.933 93.059  1.00 99.13  ? 809  TRP A CA  1 
ATOM   4486 C C   . TRP A 1 687  ? 155.712 148.648 94.345  1.00 96.62  ? 809  TRP A C   1 
ATOM   4487 O O   . TRP A 1 687  ? 155.611 147.995 95.389  1.00 98.83  ? 809  TRP A O   1 
ATOM   4488 C CB  . TRP A 1 687  ? 157.513 147.321 93.210  1.00 97.58  ? 809  TRP A CB  1 
ATOM   4489 C CG  . TRP A 1 687  ? 158.585 148.342 93.471  1.00 96.50  ? 809  TRP A CG  1 
ATOM   4490 C CD1 . TRP A 1 687  ? 159.277 149.063 92.541  1.00 93.52  ? 809  TRP A CD1 1 
ATOM   4491 C CD2 . TRP A 1 687  ? 159.088 148.750 94.747  1.00 95.06  ? 809  TRP A CD2 1 
ATOM   4492 N NE1 . TRP A 1 687  ? 160.174 149.896 93.157  1.00 90.72  ? 809  TRP A NE1 1 
ATOM   4493 C CE2 . TRP A 1 687  ? 160.072 149.732 94.512  1.00 92.25  ? 809  TRP A CE2 1 
ATOM   4494 C CE3 . TRP A 1 687  ? 158.787 148.394 96.067  1.00 95.25  ? 809  TRP A CE3 1 
ATOM   4495 C CZ2 . TRP A 1 687  ? 160.764 150.353 95.550  1.00 90.36  ? 809  TRP A CZ2 1 
ATOM   4496 C CZ3 . TRP A 1 687  ? 159.467 149.012 97.092  1.00 94.99  ? 809  TRP A CZ3 1 
ATOM   4497 C CH2 . TRP A 1 687  ? 160.442 149.983 96.830  1.00 93.46  ? 809  TRP A CH2 1 
ATOM   4498 N N   . ALA A 1 688  ? 155.465 149.956 94.303  1.00 94.08  ? 810  ALA A N   1 
ATOM   4499 C CA  . ALA A 1 688  ? 155.159 150.697 95.518  1.00 93.95  ? 810  ALA A CA  1 
ATOM   4500 C C   . ALA A 1 688  ? 154.251 151.871 95.194  1.00 92.10  ? 810  ALA A C   1 
ATOM   4501 O O   . ALA A 1 688  ? 154.517 152.622 94.254  1.00 93.03  ? 810  ALA A O   1 
ATOM   4502 C CB  . ALA A 1 688  ? 156.433 151.207 96.196  1.00 89.83  ? 810  ALA A CB  1 
ATOM   4503 N N   . VAL A 1 689  ? 153.178 152.018 95.970  1.00 89.69  ? 811  VAL A N   1 
ATOM   4504 C CA  . VAL A 1 689  ? 152.315 153.192 95.913  1.00 84.07  ? 811  VAL A CA  1 
ATOM   4505 C C   . VAL A 1 689  ? 152.287 153.793 97.310  1.00 87.96  ? 811  VAL A C   1 
ATOM   4506 O O   . VAL A 1 689  ? 151.848 153.134 98.259  1.00 90.23  ? 811  VAL A O   1 
ATOM   4507 C CB  . VAL A 1 689  ? 150.886 152.862 95.449  1.00 86.38  ? 811  VAL A CB  1 
ATOM   4508 C CG1 . VAL A 1 689  ? 150.014 154.100 95.525  1.00 86.59  ? 811  VAL A CG1 1 
ATOM   4509 C CG2 . VAL A 1 689  ? 150.877 152.304 94.058  1.00 94.47  ? 811  VAL A CG2 1 
ATOM   4510 N N   . ILE A 1 690  ? 152.744 155.035 97.441  1.00 85.08  ? 812  ILE A N   1 
ATOM   4511 C CA  . ILE A 1 690  ? 152.837 155.710 98.733  1.00 85.94  ? 812  ILE A CA  1 
ATOM   4512 C C   . ILE A 1 690  ? 151.877 156.889 98.712  1.00 87.05  ? 812  ILE A C   1 
ATOM   4513 O O   . ILE A 1 690  ? 152.039 157.814 97.909  1.00 89.51  ? 812  ILE A O   1 
ATOM   4514 C CB  . ILE A 1 690  ? 154.269 156.175 99.078  1.00 83.79  ? 812  ILE A CB  1 
ATOM   4515 C CG1 . ILE A 1 690  ? 155.292 155.026 99.230  1.00 85.69  ? 812  ILE A CG1 1 
ATOM   4516 C CG2 . ILE A 1 690  ? 154.273 157.010 100.348 1.00 87.03  ? 812  ILE A CG2 1 
ATOM   4517 C CD1 . ILE A 1 690  ? 156.056 154.563 97.979  1.00 91.05  ? 812  ILE A CD1 1 
ATOM   4518 N N   . LEU A 1 691  ? 150.888 156.861 99.601  1.00 83.32  ? 813  LEU A N   1 
ATOM   4519 C CA  . LEU A 1 691  ? 149.879 157.911 99.678  1.00 82.14  ? 813  LEU A CA  1 
ATOM   4520 C C   . LEU A 1 691  ? 150.454 159.089 100.454 1.00 92.30  ? 813  LEU A C   1 
ATOM   4521 O O   . LEU A 1 691  ? 150.968 158.920 101.564 1.00 97.83  ? 813  LEU A O   1 
ATOM   4522 C CB  . LEU A 1 691  ? 148.617 157.372 100.342 1.00 81.90  ? 813  LEU A CB  1 
ATOM   4523 C CG  . LEU A 1 691  ? 147.425 158.314 100.472 1.00 83.60  ? 813  LEU A CG  1 
ATOM   4524 C CD1 . LEU A 1 691  ? 146.933 158.764 99.110  1.00 78.97  ? 813  LEU A CD1 1 
ATOM   4525 C CD2 . LEU A 1 691  ? 146.312 157.648 101.255 1.00 87.10  ? 813  LEU A CD2 1 
ATOM   4526 N N   . LEU A 1 692  ? 150.366 160.287 99.874  1.00 90.96  ? 814  LEU A N   1 
ATOM   4527 C CA  . LEU A 1 692  ? 150.963 161.487 100.462 1.00 84.13  ? 814  LEU A CA  1 
ATOM   4528 C C   . LEU A 1 692  ? 149.915 162.220 101.294 1.00 93.44  ? 814  LEU A C   1 
ATOM   4529 O O   . LEU A 1 692  ? 149.355 163.245 100.896 1.00 100.85 ? 814  LEU A O   1 
ATOM   4530 C CB  . LEU A 1 692  ? 151.535 162.384 99.375  1.00 80.50  ? 814  LEU A CB  1 
ATOM   4531 C CG  . LEU A 1 692  ? 152.583 161.757 98.459  1.00 84.21  ? 814  LEU A CG  1 
ATOM   4532 C CD1 . LEU A 1 692  ? 153.068 162.760 97.433  1.00 85.41  ? 814  LEU A CD1 1 
ATOM   4533 C CD2 . LEU A 1 692  ? 153.738 161.247 99.277  1.00 81.64  ? 814  LEU A CD2 1 
ATOM   4534 N N   . VAL A 1 693  ? 149.651 161.679 102.477 1.00 92.43  ? 815  VAL A N   1 
ATOM   4535 C CA  . VAL A 1 693  ? 148.755 162.304 103.447 1.00 98.74  ? 815  VAL A CA  1 
ATOM   4536 C C   . VAL A 1 693  ? 149.532 162.528 104.741 1.00 106.02 ? 815  VAL A C   1 
ATOM   4537 O O   . VAL A 1 693  ? 150.545 161.853 104.973 1.00 105.70 ? 815  VAL A O   1 
ATOM   4538 C CB  . VAL A 1 693  ? 147.489 161.455 103.681 1.00 98.38  ? 815  VAL A CB  1 
ATOM   4539 C CG1 . VAL A 1 693  ? 146.599 161.460 102.457 1.00 93.54  ? 815  VAL A CG1 1 
ATOM   4540 C CG2 . VAL A 1 693  ? 147.854 160.028 104.052 1.00 98.19  ? 815  VAL A CG2 1 
ATOM   4541 N N   . PRO A 1 694  ? 149.124 163.473 105.601 1.00 110.31 ? 816  PRO A N   1 
ATOM   4542 C CA  . PRO A 1 694  ? 149.729 163.540 106.945 1.00 106.82 ? 816  PRO A CA  1 
ATOM   4543 C C   . PRO A 1 694  ? 149.271 162.442 107.895 1.00 100.58 ? 816  PRO A C   1 
ATOM   4544 O O   . PRO A 1 694  ? 149.885 162.266 108.954 1.00 99.56  ? 816  PRO A O   1 
ATOM   4545 C CB  . PRO A 1 694  ? 149.310 164.927 107.452 1.00 109.74 ? 816  PRO A CB  1 
ATOM   4546 C CG  . PRO A 1 694  ? 148.162 165.328 106.599 1.00 112.85 ? 816  PRO A CG  1 
ATOM   4547 C CD  . PRO A 1 694  ? 148.424 164.727 105.266 1.00 111.04 ? 816  PRO A CD  1 
ATOM   4548 N N   . GLU A 1 695  ? 148.215 161.691 107.557 1.00 102.46 ? 817  GLU A N   1 
ATOM   4549 C CA  . GLU A 1 695  ? 147.790 160.566 108.385 1.00 104.48 ? 817  GLU A CA  1 
ATOM   4550 C C   . GLU A 1 695  ? 148.656 159.330 108.160 1.00 104.03 ? 817  GLU A C   1 
ATOM   4551 O O   . GLU A 1 695  ? 148.571 158.370 108.931 1.00 100.76 ? 817  GLU A O   1 
ATOM   4552 C CB  . GLU A 1 695  ? 146.319 160.217 108.120 1.00 106.64 ? 817  GLU A CB  1 
ATOM   4553 C CG  . GLU A 1 695  ? 145.270 161.256 108.548 1.00 114.62 ? 817  GLU A CG  1 
ATOM   4554 C CD  . GLU A 1 695  ? 145.043 162.377 107.543 1.00 120.87 ? 817  GLU A CD  1 
ATOM   4555 O OE1 . GLU A 1 695  ? 145.650 162.348 106.452 1.00 114.75 ? 817  GLU A OE1 1 
ATOM   4556 O OE2 . GLU A 1 695  ? 144.253 163.294 107.850 1.00 128.35 ? 817  GLU A OE2 1 
ATOM   4557 N N   . SER A 1 696  ? 149.465 159.319 107.096 1.00 103.53 ? 818  SER A N   1 
ATOM   4558 C CA  . SER A 1 696  ? 150.417 158.233 106.896 1.00 99.08  ? 818  SER A CA  1 
ATOM   4559 C C   . SER A 1 696  ? 151.583 158.335 107.872 1.00 100.36 ? 818  SER A C   1 
ATOM   4560 O O   . SER A 1 696  ? 152.159 157.316 108.271 1.00 99.35  ? 818  SER A O   1 
ATOM   4561 C CB  . SER A 1 696  ? 150.919 158.239 105.454 1.00 95.44  ? 818  SER A CB  1 
ATOM   4562 O OG  . SER A 1 696  ? 151.720 157.105 105.188 1.00 103.58 ? 818  SER A OG  1 
ATOM   4563 N N   . GLN A 1 697  ? 151.946 159.554 108.267 1.00 96.43  ? 819  GLN A N   1 
ATOM   4564 C CA  . GLN A 1 697  ? 153.013 159.796 109.238 1.00 91.65  ? 819  GLN A CA  1 
ATOM   4565 C C   . GLN A 1 697  ? 152.496 160.706 110.350 1.00 93.58  ? 819  GLN A C   1 
ATOM   4566 O O   . GLN A 1 697  ? 152.739 161.918 110.331 1.00 97.12  ? 819  GLN A O   1 
ATOM   4567 C CB  . GLN A 1 697  ? 154.229 160.416 108.549 1.00 84.12  ? 819  GLN A CB  1 
ATOM   4568 C CG  . GLN A 1 697  ? 155.026 159.449 107.704 1.00 84.11  ? 819  GLN A CG  1 
ATOM   4569 C CD  . GLN A 1 697  ? 156.317 160.050 107.203 1.00 88.13  ? 819  GLN A CD  1 
ATOM   4570 O OE1 . GLN A 1 697  ? 156.490 161.266 107.212 1.00 90.03  ? 819  GLN A OE1 1 
ATOM   4571 N NE2 . GLN A 1 697  ? 157.233 159.201 106.763 1.00 93.00  ? 819  GLN A NE2 1 
ATOM   4572 N N   . PRO A 1 698  ? 151.780 160.159 111.339 1.00 92.58  ? 820  PRO A N   1 
ATOM   4573 C CA  . PRO A 1 698  ? 151.146 161.028 112.335 1.00 96.99  ? 820  PRO A CA  1 
ATOM   4574 C C   . PRO A 1 698  ? 152.090 161.437 113.456 1.00 105.01 ? 820  PRO A C   1 
ATOM   4575 O O   . PRO A 1 698  ? 153.063 160.746 113.769 1.00 104.09 ? 820  PRO A O   1 
ATOM   4576 C CB  . PRO A 1 698  ? 149.997 160.166 112.867 1.00 88.42  ? 820  PRO A CB  1 
ATOM   4577 C CG  . PRO A 1 698  ? 150.510 158.800 112.759 1.00 85.00  ? 820  PRO A CG  1 
ATOM   4578 C CD  . PRO A 1 698  ? 151.366 158.755 111.527 1.00 89.98  ? 820  PRO A CD  1 
ATOM   4579 N N   . LEU A 1 699  ? 151.790 162.591 114.051 1.00 108.16 ? 821  LEU A N   1 
ATOM   4580 C CA  . LEU A 1 699  ? 152.429 163.075 115.269 1.00 105.34 ? 821  LEU A CA  1 
ATOM   4581 C C   . LEU A 1 699  ? 151.654 162.714 116.525 1.00 103.70 ? 821  LEU A C   1 
ATOM   4582 O O   . LEU A 1 699  ? 152.235 162.706 117.615 1.00 101.98 ? 821  LEU A O   1 
ATOM   4583 C CB  . LEU A 1 699  ? 152.570 164.606 115.233 1.00 110.13 ? 821  LEU A CB  1 
ATOM   4584 C CG  . LEU A 1 699  ? 153.665 165.457 114.573 1.00 115.19 ? 821  LEU A CG  1 
ATOM   4585 C CD1 . LEU A 1 699  ? 155.012 165.220 115.210 1.00 112.38 ? 821  LEU A CD1 1 
ATOM   4586 C CD2 . LEU A 1 699  ? 153.764 165.226 113.090 1.00 105.94 ? 821  LEU A CD2 1 
ATOM   4587 N N   . THR A 1 700  ? 150.372 162.400 116.389 1.00 107.12 ? 822  THR A N   1 
ATOM   4588 C CA  . THR A 1 700  ? 149.420 162.426 117.487 1.00 110.25 ? 822  THR A CA  1 
ATOM   4589 C C   . THR A 1 700  ? 148.916 161.014 117.751 1.00 112.98 ? 822  THR A C   1 
ATOM   4590 O O   . THR A 1 700  ? 148.464 160.331 116.829 1.00 114.22 ? 822  THR A O   1 
ATOM   4591 C CB  . THR A 1 700  ? 148.261 163.373 117.141 1.00 116.51 ? 822  THR A CB  1 
ATOM   4592 O OG1 . THR A 1 700  ? 148.777 164.691 116.923 1.00 118.49 ? 822  THR A OG1 1 
ATOM   4593 C CG2 . THR A 1 700  ? 147.226 163.435 118.248 1.00 119.47 ? 822  THR A CG2 1 
ATOM   4594 N N   . SER A 1 701  ? 148.994 160.585 119.015 1.00 111.24 ? 823  SER A N   1 
ATOM   4595 C CA  . SER A 1 701  ? 148.511 159.259 119.388 1.00 117.76 ? 823  SER A CA  1 
ATOM   4596 C C   . SER A 1 701  ? 146.988 159.213 119.470 1.00 120.25 ? 823  SER A C   1 
ATOM   4597 O O   . SER A 1 701  ? 146.399 158.126 119.444 1.00 124.75 ? 823  SER A O   1 
ATOM   4598 C CB  . SER A 1 701  ? 149.129 158.838 120.719 1.00 119.35 ? 823  SER A CB  1 
ATOM   4599 O OG  . SER A 1 701  ? 148.652 157.568 121.125 1.00 120.89 ? 823  SER A OG  1 
ATOM   4600 N N   . ALA A 1 702  ? 146.348 160.377 119.635 1.00 120.46 ? 824  ALA A N   1 
ATOM   4601 C CA  . ALA A 1 702  ? 144.905 160.688 119.688 1.00 124.64 ? 824  ALA A CA  1 
ATOM   4602 C C   . ALA A 1 702  ? 144.175 160.028 120.856 1.00 129.24 ? 824  ALA A C   1 
ATOM   4603 O O   . ALA A 1 702  ? 142.946 159.928 120.808 1.00 126.61 ? 824  ALA A O   1 
ATOM   4604 C CB  . ALA A 1 702  ? 144.155 160.356 118.384 1.00 118.04 ? 824  ALA A CB  1 
ATOM   4605 N N   . GLY A 1 703  ? 144.876 159.578 121.893 1.00 128.72 ? 825  GLY A N   1 
ATOM   4606 C CA  . GLY A 1 703  ? 144.247 159.148 123.122 1.00 122.24 ? 825  GLY A CA  1 
ATOM   4607 C C   . GLY A 1 703  ? 145.010 159.664 124.322 1.00 120.52 ? 825  GLY A C   1 
ATOM   4608 O O   . GLY A 1 703  ? 146.178 159.316 124.514 1.00 122.13 ? 825  GLY A O   1 
ATOM   4609 N N   . GLY A 1 704  ? 144.369 160.493 125.139 1.00 118.99 ? 826  GLY A N   1 
ATOM   4610 C CA  . GLY A 1 704  ? 145.042 161.061 126.289 1.00 117.19 ? 826  GLY A CA  1 
ATOM   4611 C C   . GLY A 1 704  ? 144.159 161.149 127.513 1.00 120.53 ? 826  GLY A C   1 
ATOM   4612 O O   . GLY A 1 704  ? 143.102 161.785 127.481 1.00 127.27 ? 826  GLY A O   1 
ATOM   4613 N N   . LYS A 1 705  ? 144.588 160.519 128.599 1.00 114.68 ? 827  LYS A N   1 
ATOM   4614 C CA  . LYS A 1 705  ? 143.836 160.521 129.846 1.00 112.92 ? 827  LYS A CA  1 
ATOM   4615 C C   . LYS A 1 705  ? 144.800 160.364 131.014 1.00 112.23 ? 827  LYS A C   1 
ATOM   4616 O O   . LYS A 1 705  ? 145.286 159.252 131.258 1.00 112.56 ? 827  LYS A O   1 
ATOM   4617 C CB  . LYS A 1 705  ? 142.800 159.396 129.855 1.00 114.99 ? 827  LYS A CB  1 
ATOM   4618 C CG  . LYS A 1 705  ? 141.856 159.417 131.044 1.00 110.91 ? 827  LYS A CG  1 
ATOM   4619 C CD  . LYS A 1 705  ? 140.994 160.665 131.056 1.00 111.52 ? 827  LYS A CD  1 
ATOM   4620 C CE  . LYS A 1 705  ? 140.007 160.624 132.210 1.00 113.31 ? 827  LYS A CE  1 
ATOM   4621 N NZ  . LYS A 1 705  ? 138.816 161.481 131.963 1.00 114.60 ? 827  LYS A NZ  1 
ATOM   4622 N N   . PRO A 1 706  ? 145.130 161.443 131.730 1.00 109.20 ? 828  PRO A N   1 
ATOM   4623 C CA  . PRO A 1 706  ? 145.955 161.298 132.934 1.00 103.97 ? 828  PRO A CA  1 
ATOM   4624 C C   . PRO A 1 706  ? 145.154 160.699 134.077 1.00 104.09 ? 828  PRO A C   1 
ATOM   4625 O O   . PRO A 1 706  ? 143.972 161.000 134.259 1.00 108.35 ? 828  PRO A O   1 
ATOM   4626 C CB  . PRO A 1 706  ? 146.386 162.736 133.248 1.00 96.71  ? 828  PRO A CB  1 
ATOM   4627 C CG  . PRO A 1 706  ? 146.104 163.513 132.002 1.00 99.36  ? 828  PRO A CG  1 
ATOM   4628 C CD  . PRO A 1 706  ? 144.907 162.859 131.403 1.00 103.86 ? 828  PRO A CD  1 
ATOM   4629 N N   . HIS A 1 707  ? 145.809 159.839 134.848 1.00 101.97 ? 829  HIS A N   1 
ATOM   4630 C CA  . HIS A 1 707  ? 145.175 159.139 135.951 1.00 106.25 ? 829  HIS A CA  1 
ATOM   4631 C C   . HIS A 1 707  ? 146.045 159.259 137.192 1.00 109.07 ? 829  HIS A C   1 
ATOM   4632 O O   . HIS A 1 707  ? 147.192 159.715 137.122 1.00 105.35 ? 829  HIS A O   1 
ATOM   4633 C CB  . HIS A 1 707  ? 144.942 157.661 135.622 1.00 108.24 ? 829  HIS A CB  1 
ATOM   4634 C CG  . HIS A 1 707  ? 146.203 156.865 135.522 1.00 113.69 ? 829  HIS A CG  1 
ATOM   4635 N ND1 . HIS A 1 707  ? 146.606 155.976 136.495 1.00 117.18 ? 829  HIS A ND1 1 
ATOM   4636 C CD2 . HIS A 1 707  ? 147.152 156.822 134.558 1.00 112.67 ? 829  HIS A CD2 1 
ATOM   4637 C CE1 . HIS A 1 707  ? 147.752 155.426 136.136 1.00 115.35 ? 829  HIS A CE1 1 
ATOM   4638 N NE2 . HIS A 1 707  ? 148.106 155.923 134.966 1.00 113.29 ? 829  HIS A NE2 1 
ATOM   4639 N N   . SER A 1 708  ? 145.451 158.816 138.313 1.00 108.58 ? 830  SER A N   1 
ATOM   4640 C CA  . SER A 1 708  ? 146.015 158.792 139.674 1.00 107.20 ? 830  SER A CA  1 
ATOM   4641 C C   . SER A 1 708  ? 146.458 160.183 140.132 1.00 104.97 ? 830  SER A C   1 
ATOM   4642 O O   . SER A 1 708  ? 147.620 160.419 140.468 1.00 105.54 ? 830  SER A O   1 
ATOM   4643 C CB  . SER A 1 708  ? 147.154 157.770 139.803 1.00 108.66 ? 830  SER A CB  1 
ATOM   4644 O OG  . SER A 1 708  ? 146.705 156.464 139.492 1.00 109.80 ? 830  SER A OG  1 
ATOM   4645 N N   . LEU A 1 709  ? 145.503 161.109 140.108 1.00 100.15 ? 831  LEU A N   1 
ATOM   4646 C CA  . LEU A 1 709  ? 145.742 162.462 140.589 1.00 94.28  ? 831  LEU A CA  1 
ATOM   4647 C C   . LEU A 1 709  ? 145.810 162.451 142.108 1.00 95.60  ? 831  LEU A C   1 
ATOM   4648 O O   . LEU A 1 709  ? 144.895 161.954 142.773 1.00 95.72  ? 831  LEU A O   1 
ATOM   4649 C CB  . LEU A 1 709  ? 144.639 163.398 140.105 1.00 88.96  ? 831  LEU A CB  1 
ATOM   4650 C CG  . LEU A 1 709  ? 144.807 164.889 140.399 1.00 86.55  ? 831  LEU A CG  1 
ATOM   4651 C CD1 . LEU A 1 709  ? 145.980 165.460 139.632 1.00 85.80  ? 831  LEU A CD1 1 
ATOM   4652 C CD2 . LEU A 1 709  ? 143.535 165.642 140.063 1.00 85.98  ? 831  LEU A CD2 1 
ATOM   4653 N N   . LYS A 1 710  ? 146.913 162.949 142.651 1.00 92.07  ? 832  LYS A N   1 
ATOM   4654 C CA  . LYS A 1 710  ? 147.112 163.061 144.086 1.00 85.58  ? 832  LYS A CA  1 
ATOM   4655 C C   . LYS A 1 710  ? 147.536 164.484 144.400 1.00 82.15  ? 832  LYS A C   1 
ATOM   4656 O O   . LYS A 1 710  ? 148.128 165.167 143.562 1.00 90.11  ? 832  LYS A O   1 
ATOM   4657 C CB  . LYS A 1 710  ? 148.177 162.084 144.603 1.00 91.59  ? 832  LYS A CB  1 
ATOM   4658 C CG  . LYS A 1 710  ? 147.833 160.618 144.444 1.00 100.34 ? 832  LYS A CG  1 
ATOM   4659 C CD  . LYS A 1 710  ? 148.915 159.744 145.045 1.00 104.92 ? 832  LYS A CD  1 
ATOM   4660 C CE  . LYS A 1 710  ? 150.180 159.801 144.207 1.00 104.76 ? 832  LYS A CE  1 
ATOM   4661 N NZ  . LYS A 1 710  ? 149.982 159.199 142.858 1.00 107.16 ? 832  LYS A NZ  1 
ATOM   4662 N N   . ALA A 1 711  ? 147.230 164.930 145.613 1.00 82.62  ? 833  ALA A N   1 
ATOM   4663 C CA  . ALA A 1 711  ? 147.573 166.280 146.020 1.00 80.88  ? 833  ALA A CA  1 
ATOM   4664 C C   . ALA A 1 711  ? 147.856 166.323 147.512 1.00 81.75  ? 833  ALA A C   1 
ATOM   4665 O O   . ALA A 1 711  ? 147.068 165.827 148.320 1.00 85.26  ? 833  ALA A O   1 
ATOM   4666 C CB  . ALA A 1 711  ? 146.455 167.261 145.662 1.00 80.51  ? 833  ALA A CB  1 
ATOM   4667 N N   . LEU A 1 712  ? 148.996 166.912 147.861 1.00 78.54  ? 834  LEU A N   1 
ATOM   4668 C CA  . LEU A 1 712  ? 149.387 167.187 149.236 1.00 76.99  ? 834  LEU A CA  1 
ATOM   4669 C C   . LEU A 1 712  ? 149.431 168.694 149.403 1.00 78.72  ? 834  LEU A C   1 
ATOM   4670 O O   . LEU A 1 712  ? 150.010 169.389 148.565 1.00 85.88  ? 834  LEU A O   1 
ATOM   4671 C CB  . LEU A 1 712  ? 150.751 166.578 149.554 1.00 77.56  ? 834  LEU A CB  1 
ATOM   4672 C CG  . LEU A 1 712  ? 151.292 166.739 150.972 1.00 82.03  ? 834  LEU A CG  1 
ATOM   4673 C CD1 . LEU A 1 712  ? 150.435 165.991 151.974 1.00 88.25  ? 834  LEU A CD1 1 
ATOM   4674 C CD2 . LEU A 1 712  ? 152.729 166.267 151.016 1.00 79.87  ? 834  LEU A CD2 1 
ATOM   4675 N N   . LEU A 1 713  ? 148.827 169.201 150.473 1.00 77.31  ? 835  LEU A N   1 
ATOM   4676 C CA  . LEU A 1 713  ? 148.562 170.627 150.582 1.00 73.03  ? 835  LEU A CA  1 
ATOM   4677 C C   . LEU A 1 713  ? 149.132 171.194 151.870 1.00 74.71  ? 835  LEU A C   1 
ATOM   4678 O O   . LEU A 1 713  ? 149.198 170.508 152.893 1.00 81.58  ? 835  LEU A O   1 
ATOM   4679 C CB  . LEU A 1 713  ? 147.055 170.931 150.510 1.00 65.68  ? 835  LEU A CB  1 
ATOM   4680 C CG  . LEU A 1 713  ? 146.393 171.068 149.134 1.00 71.83  ? 835  LEU A CG  1 
ATOM   4681 C CD1 . LEU A 1 713  ? 146.082 169.744 148.500 1.00 78.58  ? 835  LEU A CD1 1 
ATOM   4682 C CD2 . LEU A 1 713  ? 145.128 171.875 149.227 1.00 83.13  ? 835  LEU A CD2 1 
ATOM   4683 N N   . GLY A 1 714  ? 149.552 172.452 151.799 1.00 65.87  ? 836  GLY A N   1 
ATOM   4684 C CA  . GLY A 1 714  ? 149.967 173.200 152.963 1.00 67.82  ? 836  GLY A CA  1 
ATOM   4685 C C   . GLY A 1 714  ? 149.051 174.379 153.196 1.00 69.73  ? 836  GLY A C   1 
ATOM   4686 O O   . GLY A 1 714  ? 147.916 174.380 152.722 1.00 72.84  ? 836  GLY A O   1 
ATOM   4687 N N   . ALA A 1 715  ? 149.523 175.389 153.919 1.00 72.82  ? 837  ALA A N   1 
ATOM   4688 C CA  . ALA A 1 715  ? 148.713 176.576 154.148 1.00 72.71  ? 837  ALA A CA  1 
ATOM   4689 C C   . ALA A 1 715  ? 148.695 177.505 152.945 1.00 76.68  ? 837  ALA A C   1 
ATOM   4690 O O   . ALA A 1 715  ? 147.643 178.048 152.600 1.00 83.84  ? 837  ALA A O   1 
ATOM   4691 C CB  . ALA A 1 715  ? 149.217 177.330 155.379 1.00 79.58  ? 837  ALA A CB  1 
ATOM   4692 N N   . GLN A 1 716  ? 149.841 177.696 152.296 1.00 77.96  ? 838  GLN A N   1 
ATOM   4693 C CA  . GLN A 1 716  ? 149.956 178.612 151.174 1.00 78.80  ? 838  GLN A CA  1 
ATOM   4694 C C   . GLN A 1 716  ? 150.279 177.917 149.861 1.00 77.81  ? 838  GLN A C   1 
ATOM   4695 O O   . GLN A 1 716  ? 150.380 178.594 148.833 1.00 82.09  ? 838  GLN A O   1 
ATOM   4696 C CB  . GLN A 1 716  ? 151.044 179.660 151.449 1.00 84.09  ? 838  GLN A CB  1 
ATOM   4697 C CG  . GLN A 1 716  ? 150.777 180.594 152.611 1.00 82.91  ? 838  GLN A CG  1 
ATOM   4698 C CD  . GLN A 1 716  ? 149.559 181.455 152.404 1.00 86.21  ? 838  GLN A CD  1 
ATOM   4699 O OE1 . GLN A 1 716  ? 148.542 181.264 153.059 1.00 90.59  ? 838  GLN A OE1 1 
ATOM   4700 N NE2 . GLN A 1 716  ? 149.651 182.406 151.485 1.00 88.32  ? 838  GLN A NE2 1 
ATOM   4701 N N   . ALA A 1 717  ? 150.452 176.599 149.857 1.00 73.08  ? 839  ALA A N   1 
ATOM   4702 C CA  . ALA A 1 717  ? 151.013 175.922 148.702 1.00 69.71  ? 839  ALA A CA  1 
ATOM   4703 C C   . ALA A 1 717  ? 150.509 174.489 148.650 1.00 70.05  ? 839  ALA A C   1 
ATOM   4704 O O   . ALA A 1 717  ? 150.023 173.945 149.642 1.00 77.02  ? 839  ALA A O   1 
ATOM   4705 C CB  . ALA A 1 717  ? 152.544 175.948 148.742 1.00 74.84  ? 839  ALA A CB  1 
ATOM   4706 N N   . ALA A 1 718  ? 150.637 173.880 147.474 1.00 68.22  ? 840  ALA A N   1 
ATOM   4707 C CA  . ALA A 1 718  ? 150.194 172.514 147.258 1.00 70.32  ? 840  ALA A CA  1 
ATOM   4708 C C   . ALA A 1 718  ? 151.246 171.757 146.461 1.00 76.71  ? 840  ALA A C   1 
ATOM   4709 O O   . ALA A 1 718  ? 152.040 172.347 145.728 1.00 81.09  ? 840  ALA A O   1 
ATOM   4710 C CB  . ALA A 1 718  ? 148.848 172.465 146.529 1.00 70.61  ? 840  ALA A CB  1 
ATOM   4711 N N   . LYS A 1 719  ? 151.247 170.434 146.620 1.00 76.74  ? 841  LYS A N   1 
ATOM   4712 C CA  . LYS A 1 719  ? 152.149 169.543 145.894 1.00 73.66  ? 841  LYS A CA  1 
ATOM   4713 C C   . LYS A 1 719  ? 151.305 168.501 145.177 1.00 78.93  ? 841  LYS A C   1 
ATOM   4714 O O   . LYS A 1 719  ? 150.869 167.523 145.791 1.00 80.04  ? 841  LYS A O   1 
ATOM   4715 C CB  . LYS A 1 719  ? 153.147 168.875 146.837 1.00 75.49  ? 841  LYS A CB  1 
ATOM   4716 C CG  . LYS A 1 719  ? 154.430 169.654 147.046 1.00 85.20  ? 841  LYS A CG  1 
ATOM   4717 C CD  . LYS A 1 719  ? 155.430 168.843 147.851 1.00 85.88  ? 841  LYS A CD  1 
ATOM   4718 C CE  . LYS A 1 719  ? 156.424 169.736 148.570 1.00 88.35  ? 841  LYS A CE  1 
ATOM   4719 N NZ  . LYS A 1 719  ? 156.719 170.983 147.816 1.00 87.80  ? 841  LYS A NZ  1 
ATOM   4720 N N   . ILE A 1 720  ? 151.093 168.695 143.879 1.00 81.80  ? 842  ILE A N   1 
ATOM   4721 C CA  . ILE A 1 720  ? 150.148 167.905 143.099 1.00 78.60  ? 842  ILE A CA  1 
ATOM   4722 C C   . ILE A 1 720  ? 150.933 166.986 142.175 1.00 83.98  ? 842  ILE A C   1 
ATOM   4723 O O   . ILE A 1 720  ? 151.752 167.450 141.374 1.00 88.00  ? 842  ILE A O   1 
ATOM   4724 C CB  . ILE A 1 720  ? 149.194 168.806 142.305 1.00 69.21  ? 842  ILE A CB  1 
ATOM   4725 C CG1 . ILE A 1 720  ? 148.351 169.628 143.268 1.00 78.24  ? 842  ILE A CG1 1 
ATOM   4726 C CG2 . ILE A 1 720  ? 148.284 167.993 141.410 1.00 77.27  ? 842  ILE A CG2 1 
ATOM   4727 C CD1 . ILE A 1 720  ? 147.631 170.740 142.609 1.00 80.53  ? 842  ILE A CD1 1 
ATOM   4728 N N   . SER A 1 721  ? 150.688 165.685 142.290 1.00 85.55  ? 843  SER A N   1 
ATOM   4729 C CA  . SER A 1 721  ? 151.321 164.686 141.446 1.00 85.16  ? 843  SER A CA  1 
ATOM   4730 C C   . SER A 1 721  ? 150.252 163.832 140.788 1.00 87.66  ? 843  SER A C   1 
ATOM   4731 O O   . SER A 1 721  ? 149.351 163.327 141.462 1.00 93.05  ? 843  SER A O   1 
ATOM   4732 C CB  . SER A 1 721  ? 152.272 163.805 142.257 1.00 94.35  ? 843  SER A CB  1 
ATOM   4733 O OG  . SER A 1 721  ? 151.554 162.966 143.143 1.00 98.92  ? 843  SER A OG  1 
ATOM   4734 N N   . TRP A 1 722  ? 150.351 163.681 139.472 1.00 89.64  ? 844  TRP A N   1 
ATOM   4735 C CA  . TRP A 1 722  ? 149.548 162.735 138.715 1.00 92.37  ? 844  TRP A CA  1 
ATOM   4736 C C   . TRP A 1 722  ? 150.497 161.789 137.994 1.00 98.45  ? 844  TRP A C   1 
ATOM   4737 O O   . TRP A 1 722  ? 151.716 161.847 138.170 1.00 99.30  ? 844  TRP A O   1 
ATOM   4738 C CB  . TRP A 1 722  ? 148.615 163.452 137.730 1.00 89.28  ? 844  TRP A CB  1 
ATOM   4739 C CG  . TRP A 1 722  ? 149.311 164.393 136.804 1.00 88.97  ? 844  TRP A CG  1 
ATOM   4740 C CD1 . TRP A 1 722  ? 149.772 164.114 135.556 1.00 89.84  ? 844  TRP A CD1 1 
ATOM   4741 C CD2 . TRP A 1 722  ? 149.627 165.767 137.052 1.00 89.91  ? 844  TRP A CD2 1 
ATOM   4742 N NE1 . TRP A 1 722  ? 150.356 165.226 135.008 1.00 91.73  ? 844  TRP A NE1 1 
ATOM   4743 C CE2 . TRP A 1 722  ? 150.282 166.256 135.905 1.00 89.04  ? 844  TRP A CE2 1 
ATOM   4744 C CE3 . TRP A 1 722  ? 149.421 166.632 138.134 1.00 87.86  ? 844  TRP A CE3 1 
ATOM   4745 C CZ2 . TRP A 1 722  ? 150.734 167.571 135.806 1.00 88.11  ? 844  TRP A CZ2 1 
ATOM   4746 C CZ3 . TRP A 1 722  ? 149.871 167.940 138.036 1.00 84.59  ? 844  TRP A CZ3 1 
ATOM   4747 C CH2 . TRP A 1 722  ? 150.518 168.395 136.879 1.00 85.31  ? 844  TRP A CH2 1 
ATOM   4748 N N   . LYS A 1 723  ? 149.938 160.905 137.179 1.00 103.13 ? 845  LYS A N   1 
ATOM   4749 C CA  . LYS A 1 723  ? 150.738 159.980 136.394 1.00 105.28 ? 845  LYS A CA  1 
ATOM   4750 C C   . LYS A 1 723  ? 150.551 160.248 134.909 1.00 104.03 ? 845  LYS A C   1 
ATOM   4751 O O   . LYS A 1 723  ? 149.712 161.058 134.504 1.00 106.13 ? 845  LYS A O   1 
ATOM   4752 C CB  . LYS A 1 723  ? 150.393 158.520 136.709 1.00 108.58 ? 845  LYS A CB  1 
ATOM   4753 C CG  . LYS A 1 723  ? 150.775 158.090 138.113 1.00 109.74 ? 845  LYS A CG  1 
ATOM   4754 C CD  . LYS A 1 723  ? 150.464 156.624 138.354 1.00 115.02 ? 845  LYS A CD  1 
ATOM   4755 C CE  . LYS A 1 723  ? 150.776 156.224 139.786 1.00 118.90 ? 845  LYS A CE  1 
ATOM   4756 N NZ  . LYS A 1 723  ? 152.238 156.267 140.063 1.00 120.93 ? 845  LYS A NZ  1 
ATOM   4757 N N   . GLU A 1 724  ? 151.351 159.552 134.105 1.00 104.33 ? 846  GLU A N   1 
ATOM   4758 C CA  . GLU A 1 724  ? 151.296 159.656 132.660 1.00 106.05 ? 846  GLU A CA  1 
ATOM   4759 C C   . GLU A 1 724  ? 150.053 158.936 132.140 1.00 114.19 ? 846  GLU A C   1 
ATOM   4760 O O   . GLU A 1 724  ? 149.493 158.087 132.839 1.00 116.18 ? 846  GLU A O   1 
ATOM   4761 C CB  . GLU A 1 724  ? 152.549 159.029 132.048 1.00 110.64 ? 846  GLU A CB  1 
ATOM   4762 C CG  . GLU A 1 724  ? 153.863 159.736 132.360 1.00 111.56 ? 846  GLU A CG  1 
ATOM   4763 C CD  . GLU A 1 724  ? 153.983 161.116 131.749 1.00 118.16 ? 846  GLU A CD  1 
ATOM   4764 O OE1 . GLU A 1 724  ? 153.424 161.347 130.655 1.00 118.98 ? 846  GLU A OE1 1 
ATOM   4765 O OE2 . GLU A 1 724  ? 154.634 161.980 132.371 1.00 119.44 ? 846  GLU A OE2 1 
ATOM   4766 N N   . PRO A 1 725  ? 149.567 159.296 130.945 1.00 113.78 ? 847  PRO A N   1 
ATOM   4767 C CA  . PRO A 1 725  ? 148.555 158.465 130.282 1.00 112.17 ? 847  PRO A CA  1 
ATOM   4768 C C   . PRO A 1 725  ? 149.124 157.107 129.893 1.00 115.63 ? 847  PRO A C   1 
ATOM   4769 O O   . PRO A 1 725  ? 150.285 156.992 129.495 1.00 115.83 ? 847  PRO A O   1 
ATOM   4770 C CB  . PRO A 1 725  ? 148.174 159.293 129.053 1.00 109.98 ? 847  PRO A CB  1 
ATOM   4771 C CG  . PRO A 1 725  ? 148.380 160.685 129.490 1.00 109.48 ? 847  PRO A CG  1 
ATOM   4772 C CD  . PRO A 1 725  ? 149.625 160.638 130.336 1.00 109.56 ? 847  PRO A CD  1 
ATOM   4773 N N   . GLU A 1 726  ? 148.295 156.075 130.043 1.00 113.17 ? 848  GLU A N   1 
ATOM   4774 C CA  . GLU A 1 726  ? 148.770 154.701 130.054 1.00 112.80 ? 848  GLU A CA  1 
ATOM   4775 C C   . GLU A 1 726  ? 149.071 154.199 128.646 1.00 116.24 ? 848  GLU A C   1 
ATOM   4776 O O   . GLU A 1 726  ? 148.554 154.698 127.644 1.00 115.88 ? 848  GLU A O   1 
ATOM   4777 C CB  . GLU A 1 726  ? 147.748 153.789 130.727 1.00 109.93 ? 848  GLU A CB  1 
ATOM   4778 C CG  . GLU A 1 726  ? 147.864 153.765 132.236 1.00 115.29 ? 848  GLU A CG  1 
ATOM   4779 C CD  . GLU A 1 726  ? 147.017 152.685 132.871 1.00 122.18 ? 848  GLU A CD  1 
ATOM   4780 O OE1 . GLU A 1 726  ? 146.537 151.796 132.138 1.00 126.56 ? 848  GLU A OE1 1 
ATOM   4781 O OE2 . GLU A 1 726  ? 146.823 152.731 134.105 1.00 120.97 ? 848  GLU A OE2 1 
ATOM   4782 N N   . ARG A 1 727  ? 149.933 153.192 128.591 1.00 110.29 ? 849  ARG A N   1 
ATOM   4783 C CA  . ARG A 1 727  ? 150.446 152.654 127.343 1.00 102.27 ? 849  ARG A CA  1 
ATOM   4784 C C   . ARG A 1 727  ? 149.534 151.532 126.867 1.00 100.44 ? 849  ARG A C   1 
ATOM   4785 O O   . ARG A 1 727  ? 149.118 150.684 127.662 1.00 100.47 ? 849  ARG A O   1 
ATOM   4786 C CB  . ARG A 1 727  ? 151.877 152.151 127.541 1.00 97.47  ? 849  ARG A CB  1 
ATOM   4787 C CG  . ARG A 1 727  ? 152.579 151.666 126.293 1.00 98.48  ? 849  ARG A CG  1 
ATOM   4788 C CD  . ARG A 1 727  ? 153.985 151.208 126.614 1.00 102.44 ? 849  ARG A CD  1 
ATOM   4789 N NE  . ARG A 1 727  ? 153.993 150.013 127.448 1.00 114.82 ? 849  ARG A NE  1 
ATOM   4790 C CZ  . ARG A 1 727  ? 155.078 149.503 128.014 1.00 115.64 ? 849  ARG A CZ  1 
ATOM   4791 N NH1 . ARG A 1 727  ? 156.267 150.059 127.854 1.00 110.75 ? 849  ARG A NH1 1 
ATOM   4792 N NH2 . ARG A 1 727  ? 154.966 148.407 128.759 1.00 111.89 ? 849  ARG A NH2 1 
ATOM   4793 N N   . ASN A 1 728  ? 149.221 151.541 125.571 1.00 93.97  ? 850  ASN A N   1 
ATOM   4794 C CA  . ASN A 1 728  ? 148.447 150.488 124.936 1.00 85.10  ? 850  ASN A CA  1 
ATOM   4795 C C   . ASN A 1 728  ? 149.272 149.201 124.838 1.00 90.50  ? 850  ASN A C   1 
ATOM   4796 O O   . ASN A 1 728  ? 150.503 149.239 124.915 1.00 95.45  ? 850  ASN A O   1 
ATOM   4797 C CB  . ASN A 1 728  ? 148.008 150.951 123.543 1.00 81.58  ? 850  ASN A CB  1 
ATOM   4798 C CG  . ASN A 1 728  ? 147.198 152.219 123.581 1.00 94.10  ? 850  ASN A CG  1 
ATOM   4799 O OD1 . ASN A 1 728  ? 146.653 152.589 124.620 1.00 105.23 ? 850  ASN A OD1 1 
ATOM   4800 N ND2 . ASN A 1 728  ? 147.103 152.892 122.443 1.00 96.99  ? 850  ASN A ND2 1 
ATOM   4801 N N   . PRO A 1 729  ? 148.621 148.039 124.665 1.00 83.63  ? 851  PRO A N   1 
ATOM   4802 C CA  . PRO A 1 729  ? 149.377 146.828 124.293 1.00 80.97  ? 851  PRO A CA  1 
ATOM   4803 C C   . PRO A 1 729  ? 149.970 146.851 122.890 1.00 84.24  ? 851  PRO A C   1 
ATOM   4804 O O   . PRO A 1 729  ? 150.877 146.057 122.614 1.00 89.72  ? 851  PRO A O   1 
ATOM   4805 C CB  . PRO A 1 729  ? 148.334 145.714 124.427 1.00 81.55  ? 851  PRO A CB  1 
ATOM   4806 C CG  . PRO A 1 729  ? 147.383 146.232 125.419 1.00 80.94  ? 851  PRO A CG  1 
ATOM   4807 C CD  . PRO A 1 729  ? 147.256 147.677 125.094 1.00 78.21  ? 851  PRO A CD  1 
ATOM   4808 N N   . TYR A 1 730  ? 149.494 147.722 122.000 1.00 78.44  ? 852  TYR A N   1 
ATOM   4809 C CA  . TYR A 1 730  ? 150.066 147.923 120.681 1.00 74.02  ? 852  TYR A CA  1 
ATOM   4810 C C   . TYR A 1 730  ? 151.112 149.031 120.654 1.00 80.62  ? 852  TYR A C   1 
ATOM   4811 O O   . TYR A 1 730  ? 151.514 149.464 119.570 1.00 89.91  ? 852  TYR A O   1 
ATOM   4812 C CB  . TYR A 1 730  ? 148.956 148.225 119.683 1.00 75.48  ? 852  TYR A CB  1 
ATOM   4813 C CG  . TYR A 1 730  ? 147.755 147.342 119.846 1.00 78.54  ? 852  TYR A CG  1 
ATOM   4814 C CD1 . TYR A 1 730  ? 146.553 147.849 120.352 1.00 81.93  ? 852  TYR A CD1 1 
ATOM   4815 C CD2 . TYR A 1 730  ? 147.826 145.994 119.501 1.00 74.30  ? 852  TYR A CD2 1 
ATOM   4816 C CE1 . TYR A 1 730  ? 145.445 147.023 120.506 1.00 78.88  ? 852  TYR A CE1 1 
ATOM   4817 C CE2 . TYR A 1 730  ? 146.733 145.166 119.646 1.00 71.33  ? 852  TYR A CE2 1 
ATOM   4818 C CZ  . TYR A 1 730  ? 145.553 145.684 120.146 1.00 76.28  ? 852  TYR A CZ  1 
ATOM   4819 O OH  . TYR A 1 730  ? 144.477 144.845 120.288 1.00 86.34  ? 852  TYR A OH  1 
ATOM   4820 N N   . GLN A 1 731  ? 151.560 149.500 121.814 1.00 80.13  ? 853  GLN A N   1 
ATOM   4821 C CA  . GLN A 1 731  ? 152.585 150.527 121.897 1.00 82.24  ? 853  GLN A CA  1 
ATOM   4822 C C   . GLN A 1 731  ? 153.760 150.005 122.706 1.00 87.87  ? 853  GLN A C   1 
ATOM   4823 O O   . GLN A 1 731  ? 153.574 149.379 123.754 1.00 91.15  ? 853  GLN A O   1 
ATOM   4824 C CB  . GLN A 1 731  ? 152.037 151.804 122.532 1.00 82.77  ? 853  GLN A CB  1 
ATOM   4825 C CG  . GLN A 1 731  ? 151.036 152.529 121.664 1.00 87.27  ? 853  GLN A CG  1 
ATOM   4826 C CD  . GLN A 1 731  ? 150.573 153.828 122.274 1.00 92.52  ? 853  GLN A CD  1 
ATOM   4827 O OE1 . GLN A 1 731  ? 150.578 153.990 123.491 1.00 96.61  ? 853  GLN A OE1 1 
ATOM   4828 N NE2 . GLN A 1 731  ? 150.167 154.766 121.428 1.00 89.46  ? 853  GLN A NE2 1 
ATOM   4829 N N   . SER A 1 732  ? 154.967 150.266 122.217 1.00 89.16  ? 854  SER A N   1 
ATOM   4830 C CA  . SER A 1 732  ? 156.184 149.815 122.867 1.00 91.59  ? 854  SER A CA  1 
ATOM   4831 C C   . SER A 1 732  ? 156.690 150.882 123.828 1.00 99.18  ? 854  SER A C   1 
ATOM   4832 O O   . SER A 1 732  ? 156.052 151.911 124.056 1.00 104.67 ? 854  SER A O   1 
ATOM   4833 C CB  . SER A 1 732  ? 157.256 149.479 121.831 1.00 89.93  ? 854  SER A CB  1 
ATOM   4834 O OG  . SER A 1 732  ? 157.806 150.656 121.277 1.00 87.81  ? 854  SER A OG  1 
ATOM   4835 N N   . ALA A 1 733  ? 157.887 150.645 124.371 1.00 96.74  ? 855  ALA A N   1 
ATOM   4836 C CA  . ALA A 1 733  ? 158.491 151.609 125.284 1.00 95.83  ? 855  ALA A CA  1 
ATOM   4837 C C   . ALA A 1 733  ? 159.139 152.769 124.538 1.00 97.08  ? 855  ALA A C   1 
ATOM   4838 O O   . ALA A 1 733  ? 159.450 153.798 125.146 1.00 101.04 ? 855  ALA A O   1 
ATOM   4839 C CB  . ALA A 1 733  ? 159.516 150.914 126.178 1.00 95.65  ? 855  ALA A CB  1 
ATOM   4840 N N   . ASP A 1 734  ? 159.352 152.625 123.229 1.00 95.37  ? 856  ASP A N   1 
ATOM   4841 C CA  . ASP A 1 734  ? 159.873 153.689 122.384 1.00 94.74  ? 856  ASP A CA  1 
ATOM   4842 C C   . ASP A 1 734  ? 158.773 154.492 121.700 1.00 96.38  ? 856  ASP A C   1 
ATOM   4843 O O   . ASP A 1 734  ? 159.025 155.106 120.659 1.00 95.80  ? 856  ASP A O   1 
ATOM   4844 C CB  . ASP A 1 734  ? 160.818 153.107 121.335 1.00 93.70  ? 856  ASP A CB  1 
ATOM   4845 C CG  . ASP A 1 734  ? 161.966 152.349 121.951 1.00 105.76 ? 856  ASP A CG  1 
ATOM   4846 O OD1 . ASP A 1 734  ? 163.106 152.848 121.891 1.00 111.74 ? 856  ASP A OD1 1 
ATOM   4847 O OD2 . ASP A 1 734  ? 161.728 151.253 122.500 1.00 106.06 ? 856  ASP A OD2 1 
ATOM   4848 N N   . ALA A 1 735  ? 157.566 154.505 122.259 1.00 91.69  ? 857  ALA A N   1 
ATOM   4849 C CA  . ALA A 1 735  ? 156.461 155.229 121.659 1.00 96.68  ? 857  ALA A CA  1 
ATOM   4850 C C   . ALA A 1 735  ? 156.566 156.722 121.955 1.00 108.81 ? 857  ALA A C   1 
ATOM   4851 O O   . ALA A 1 735  ? 157.396 157.172 122.750 1.00 115.66 ? 857  ALA A O   1 
ATOM   4852 C CB  . ALA A 1 735  ? 155.127 154.690 122.172 1.00 92.65  ? 857  ALA A CB  1 
ATOM   4853 N N   . ALA A 1 736  ? 155.706 157.495 121.296 1.00 106.56 ? 858  ALA A N   1 
ATOM   4854 C CA  . ALA A 1 736  ? 155.650 158.936 121.506 1.00 104.97 ? 858  ALA A CA  1 
ATOM   4855 C C   . ALA A 1 736  ? 154.963 159.230 122.832 1.00 112.79 ? 858  ALA A C   1 
ATOM   4856 O O   . ALA A 1 736  ? 153.742 159.083 122.952 1.00 111.06 ? 858  ALA A O   1 
ATOM   4857 C CB  . ALA A 1 736  ? 154.911 159.614 120.358 1.00 98.88  ? 858  ALA A CB  1 
ATOM   4858 N N   . ARG A 1 737  ? 155.728 159.687 123.819 1.00 114.68 ? 859  ARG A N   1 
ATOM   4859 C CA  . ARG A 1 737  ? 155.140 160.089 125.118 1.00 113.85 ? 859  ARG A CA  1 
ATOM   4860 C C   . ARG A 1 737  ? 155.516 161.553 125.321 1.00 115.50 ? 859  ARG A C   1 
ATOM   4861 O O   . ARG A 1 737  ? 156.290 161.829 126.249 1.00 119.98 ? 859  ARG A O   1 
ATOM   4862 C CB  . ARG A 1 737  ? 155.758 159.237 126.227 1.00 118.09 ? 859  ARG A CB  1 
ATOM   4863 C CG  . ARG A 1 737  ? 155.818 157.750 125.912 1.00 115.11 ? 859  ARG A CG  1 
ATOM   4864 C CD  . ARG A 1 737  ? 154.504 157.047 126.189 1.00 115.97 ? 859  ARG A CD  1 
ATOM   4865 N NE  . ARG A 1 737  ? 154.266 156.976 127.622 1.00 126.26 ? 859  ARG A NE  1 
ATOM   4866 C CZ  . ARG A 1 737  ? 153.183 156.453 128.181 1.00 124.78 ? 859  ARG A CZ  1 
ATOM   4867 N NH1 . ARG A 1 737  ? 152.221 155.958 127.422 1.00 119.69 ? 859  ARG A NH1 1 
ATOM   4868 N NH2 . ARG A 1 737  ? 153.062 156.433 129.495 1.00 116.87 ? 859  ARG A NH2 1 
ATOM   4869 N N   . SER A 1 738  ? 154.998 162.454 124.486 1.00 112.65 ? 860  SER A N   1 
ATOM   4870 C CA  . SER A 1 738  ? 155.434 163.873 124.551 1.00 113.83 ? 860  SER A CA  1 
ATOM   4871 C C   . SER A 1 738  ? 154.316 164.798 125.037 1.00 115.23 ? 860  SER A C   1 
ATOM   4872 O O   . SER A 1 738  ? 154.299 165.964 124.618 1.00 113.01 ? 860  SER A O   1 
ATOM   4873 C CB  . SER A 1 738  ? 155.981 164.320 123.237 1.00 114.07 ? 860  SER A CB  1 
ATOM   4874 O OG  . SER A 1 738  ? 156.747 165.505 123.386 1.00 120.11 ? 860  SER A OG  1 
ATOM   4875 N N   . TRP A 1 739  ? 153.406 164.290 125.867 1.00 115.42 ? 861  TRP A N   1 
ATOM   4876 C CA  . TRP A 1 739  ? 152.262 165.100 126.355 1.00 111.34 ? 861  TRP A CA  1 
ATOM   4877 C C   . TRP A 1 739  ? 152.698 166.199 127.319 1.00 108.29 ? 861  TRP A C   1 
ATOM   4878 O O   . TRP A 1 739  ? 153.668 165.974 128.055 1.00 108.89 ? 861  TRP A O   1 
ATOM   4879 C CB  . TRP A 1 739  ? 151.234 164.212 127.057 1.00 109.47 ? 861  TRP A CB  1 
ATOM   4880 C CG  . TRP A 1 739  ? 150.634 163.125 126.227 1.00 111.90 ? 861  TRP A CG  1 
ATOM   4881 C CD1 . TRP A 1 739  ? 149.709 163.253 125.234 1.00 111.91 ? 861  TRP A CD1 1 
ATOM   4882 C CD2 . TRP A 1 739  ? 150.888 161.718 126.365 1.00 112.16 ? 861  TRP A CD2 1 
ATOM   4883 N NE1 . TRP A 1 739  ? 149.386 162.022 124.729 1.00 113.06 ? 861  TRP A NE1 1 
ATOM   4884 C CE2 . TRP A 1 739  ? 150.094 161.063 125.404 1.00 114.46 ? 861  TRP A CE2 1 
ATOM   4885 C CE3 . TRP A 1 739  ? 151.715 160.957 127.196 1.00 110.77 ? 861  TRP A CE3 1 
ATOM   4886 C CZ2 . TRP A 1 739  ? 150.106 159.678 125.253 1.00 115.28 ? 861  TRP A CZ2 1 
ATOM   4887 C CZ3 . TRP A 1 739  ? 151.724 159.591 127.049 1.00 115.60 ? 861  TRP A CZ3 1 
ATOM   4888 C CH2 . TRP A 1 739  ? 150.931 158.962 126.089 1.00 118.15 ? 861  TRP A CH2 1 
ATOM   4889 N N   . SER A 1 740  ? 152.022 167.349 127.291 1.00 105.00 ? 862  SER A N   1 
ATOM   4890 C CA  . SER A 1 740  ? 152.234 168.412 128.303 1.00 102.07 ? 862  SER A CA  1 
ATOM   4891 C C   . SER A 1 740  ? 150.921 168.415 129.080 1.00 101.18 ? 862  SER A C   1 
ATOM   4892 O O   . SER A 1 740  ? 150.060 167.608 128.707 1.00 105.86 ? 862  SER A O   1 
ATOM   4893 C CB  . SER A 1 740  ? 152.522 169.737 127.686 1.00 101.97 ? 862  SER A CB  1 
ATOM   4894 O OG  . SER A 1 740  ? 151.393 170.218 126.979 1.00 112.31 ? 862  SER A OG  1 
ATOM   4895 N N   . TYR A 1 741  ? 150.733 169.270 130.083 1.00 95.00  ? 863  TYR A N   1 
ATOM   4896 C CA  . TYR A 1 741  ? 149.554 169.178 130.921 1.00 92.56  ? 863  TYR A CA  1 
ATOM   4897 C C   . TYR A 1 741  ? 148.962 170.549 131.198 1.00 96.01  ? 863  TYR A C   1 
ATOM   4898 O O   . TYR A 1 741  ? 149.656 171.569 131.170 1.00 102.31 ? 863  TYR A O   1 
ATOM   4899 C CB  . TYR A 1 741  ? 149.860 168.474 132.243 1.00 87.84  ? 863  TYR A CB  1 
ATOM   4900 C CG  . TYR A 1 741  ? 150.306 167.050 132.054 1.00 90.70  ? 863  TYR A CG  1 
ATOM   4901 C CD1 . TYR A 1 741  ? 151.666 166.728 132.017 1.00 94.23  ? 863  TYR A CD1 1 
ATOM   4902 C CD2 . TYR A 1 741  ? 149.364 166.029 131.887 1.00 94.74  ? 863  TYR A CD2 1 
ATOM   4903 C CE1 . TYR A 1 741  ? 152.081 165.422 131.834 1.00 98.91  ? 863  TYR A CE1 1 
ATOM   4904 C CE2 . TYR A 1 741  ? 149.768 164.713 131.702 1.00 98.72  ? 863  TYR A CE2 1 
ATOM   4905 C CZ  . TYR A 1 741  ? 151.127 164.428 131.678 1.00 103.22 ? 863  TYR A CZ  1 
ATOM   4906 O OH  . TYR A 1 741  ? 151.540 163.140 131.496 1.00 112.06 ? 863  TYR A OH  1 
ATOM   4907 N N   . GLU A 1 742  ? 147.657 170.552 131.444 1.00 85.88  ? 864  GLU A N   1 
ATOM   4908 C CA  . GLU A 1 742  ? 146.920 171.722 131.880 1.00 85.37  ? 864  GLU A CA  1 
ATOM   4909 C C   . GLU A 1 742  ? 146.147 171.367 133.139 1.00 92.33  ? 864  GLU A C   1 
ATOM   4910 O O   . GLU A 1 742  ? 145.329 170.445 133.128 1.00 100.93 ? 864  GLU A O   1 
ATOM   4911 C CB  . GLU A 1 742  ? 145.967 172.212 130.790 1.00 92.27  ? 864  GLU A CB  1 
ATOM   4912 C CG  . GLU A 1 742  ? 145.040 173.309 131.254 1.00 99.10  ? 864  GLU A CG  1 
ATOM   4913 C CD  . GLU A 1 742  ? 144.188 173.875 130.143 1.00 106.36 ? 864  GLU A CD  1 
ATOM   4914 O OE1 . GLU A 1 742  ? 144.373 173.464 128.979 1.00 109.44 ? 864  GLU A OE1 1 
ATOM   4915 O OE2 . GLU A 1 742  ? 143.324 174.728 130.434 1.00 105.41 ? 864  GLU A OE2 1 
ATOM   4916 N N   . LEU A 1 743  ? 146.409 172.095 134.217 1.00 93.84  ? 865  LEU A N   1 
ATOM   4917 C CA  . LEU A 1 743  ? 145.764 171.847 135.497 1.00 87.62  ? 865  LEU A CA  1 
ATOM   4918 C C   . LEU A 1 743  ? 144.779 172.965 135.803 1.00 89.44  ? 865  LEU A C   1 
ATOM   4919 O O   . LEU A 1 743  ? 145.119 174.149 135.752 1.00 95.31  ? 865  LEU A O   1 
ATOM   4920 C CB  . LEU A 1 743  ? 146.806 171.739 136.613 1.00 83.33  ? 865  LEU A CB  1 
ATOM   4921 C CG  . LEU A 1 743  ? 146.320 171.545 138.050 1.00 84.76  ? 865  LEU A CG  1 
ATOM   4922 C CD1 . LEU A 1 743  ? 145.988 170.091 138.326 1.00 87.89  ? 865  LEU A CD1 1 
ATOM   4923 C CD2 . LEU A 1 743  ? 147.363 172.038 139.026 1.00 80.21  ? 865  LEU A CD2 1 
ATOM   4924 N N   . GLU A 1 744  ? 143.546 172.578 136.114 1.00 87.40  ? 866  GLU A N   1 
ATOM   4925 C CA  . GLU A 1 744  ? 142.486 173.520 136.444 1.00 87.41  ? 866  GLU A CA  1 
ATOM   4926 C C   . GLU A 1 744  ? 142.304 173.553 137.949 1.00 87.86  ? 866  GLU A C   1 
ATOM   4927 O O   . GLU A 1 744  ? 142.065 172.515 138.570 1.00 93.42  ? 866  GLU A O   1 
ATOM   4928 C CB  . GLU A 1 744  ? 141.164 173.140 135.780 1.00 89.76  ? 866  GLU A CB  1 
ATOM   4929 C CG  . GLU A 1 744  ? 140.065 174.166 135.981 1.00 93.16  ? 866  GLU A CG  1 
ATOM   4930 C CD  . GLU A 1 744  ? 138.763 173.769 135.316 1.00 100.67 ? 866  GLU A CD  1 
ATOM   4931 O OE1 . GLU A 1 744  ? 138.678 172.638 134.799 1.00 102.94 ? 866  GLU A OE1 1 
ATOM   4932 O OE2 . GLU A 1 744  ? 137.825 174.592 135.305 1.00 103.59 ? 866  GLU A OE2 1 
ATOM   4933 N N   . VAL A 1 745  ? 142.415 174.742 138.530 1.00 88.09  ? 867  VAL A N   1 
ATOM   4934 C CA  . VAL A 1 745  ? 142.205 174.948 139.955 1.00 84.03  ? 867  VAL A CA  1 
ATOM   4935 C C   . VAL A 1 745  ? 140.928 175.752 140.116 1.00 89.60  ? 867  VAL A C   1 
ATOM   4936 O O   . VAL A 1 745  ? 140.866 176.918 139.708 1.00 94.45  ? 867  VAL A O   1 
ATOM   4937 C CB  . VAL A 1 745  ? 143.389 175.668 140.613 1.00 85.56  ? 867  VAL A CB  1 
ATOM   4938 C CG1 . VAL A 1 745  ? 143.206 175.716 142.119 1.00 86.45  ? 867  VAL A CG1 1 
ATOM   4939 C CG2 . VAL A 1 745  ? 144.698 174.996 140.245 1.00 89.03  ? 867  VAL A CG2 1 
ATOM   4940 N N   . LEU A 1 746  ? 139.914 175.134 140.709 1.00 90.68  ? 868  LEU A N   1 
ATOM   4941 C CA  . LEU A 1 746  ? 138.623 175.764 140.935 1.00 91.55  ? 868  LEU A CA  1 
ATOM   4942 C C   . LEU A 1 746  ? 138.448 176.052 142.415 1.00 94.71  ? 868  LEU A C   1 
ATOM   4943 O O   . LEU A 1 746  ? 138.501 175.134 143.237 1.00 95.47  ? 868  LEU A O   1 
ATOM   4944 C CB  . LEU A 1 746  ? 137.480 174.875 140.442 1.00 94.56  ? 868  LEU A CB  1 
ATOM   4945 C CG  . LEU A 1 746  ? 136.073 175.456 140.579 1.00 96.63  ? 868  LEU A CG  1 
ATOM   4946 C CD1 . LEU A 1 746  ? 135.905 176.709 139.756 1.00 103.89 ? 868  LEU A CD1 1 
ATOM   4947 C CD2 . LEU A 1 746  ? 135.046 174.425 140.171 1.00 99.31  ? 868  LEU A CD2 1 
ATOM   4948 N N   . ASP A 1 747  ? 138.251 177.323 142.745 1.00 94.29  ? 869  ASP A N   1 
ATOM   4949 C CA  . ASP A 1 747  ? 137.803 177.699 144.077 1.00 89.74  ? 869  ASP A CA  1 
ATOM   4950 C C   . ASP A 1 747  ? 136.348 177.285 144.211 1.00 100.57 ? 869  ASP A C   1 
ATOM   4951 O O   . ASP A 1 747  ? 135.536 177.579 143.331 1.00 105.56 ? 869  ASP A O   1 
ATOM   4952 C CB  . ASP A 1 747  ? 137.969 179.200 144.290 1.00 92.59  ? 869  ASP A CB  1 
ATOM   4953 C CG  . ASP A 1 747  ? 137.858 179.596 145.741 1.00 97.70  ? 869  ASP A CG  1 
ATOM   4954 O OD1 . ASP A 1 747  ? 137.975 178.708 146.606 1.00 97.51  ? 869  ASP A OD1 1 
ATOM   4955 O OD2 . ASP A 1 747  ? 137.654 180.796 146.019 1.00 102.40 ? 869  ASP A OD2 1 
ATOM   4956 N N   . VAL A 1 748  ? 136.016 176.575 145.288 1.00 99.51  ? 870  VAL A N   1 
ATOM   4957 C CA  . VAL A 1 748  ? 134.673 176.016 145.407 1.00 95.65  ? 870  VAL A CA  1 
ATOM   4958 C C   . VAL A 1 748  ? 133.708 177.067 145.945 1.00 99.47  ? 870  VAL A C   1 
ATOM   4959 O O   . VAL A 1 748  ? 132.548 177.147 145.517 1.00 104.30 ? 870  VAL A O   1 
ATOM   4960 C CB  . VAL A 1 748  ? 134.716 174.745 146.278 1.00 87.50  ? 870  VAL A CB  1 
ATOM   4961 C CG1 . VAL A 1 748  ? 133.394 173.994 146.251 1.00 92.37  ? 870  VAL A CG1 1 
ATOM   4962 C CG2 . VAL A 1 748  ? 135.818 173.834 145.791 1.00 90.28  ? 870  VAL A CG2 1 
ATOM   4963 N N   . ALA A 1 749  ? 134.189 177.923 146.850 1.00 96.16  ? 871  ALA A N   1 
ATOM   4964 C CA  . ALA A 1 749  ? 133.318 178.876 147.534 1.00 99.42  ? 871  ALA A CA  1 
ATOM   4965 C C   . ALA A 1 749  ? 132.965 180.068 146.646 1.00 104.68 ? 871  ALA A C   1 
ATOM   4966 O O   . ALA A 1 749  ? 131.910 180.689 146.819 1.00 106.60 ? 871  ALA A O   1 
ATOM   4967 C CB  . ALA A 1 749  ? 133.980 179.348 148.826 1.00 95.46  ? 871  ALA A CB  1 
ATOM   4968 N N   . SER A 1 750  ? 133.833 180.406 145.693 1.00 103.25 ? 872  SER A N   1 
ATOM   4969 C CA  . SER A 1 750  ? 133.615 181.580 144.856 1.00 103.04 ? 872  SER A CA  1 
ATOM   4970 C C   . SER A 1 750  ? 133.300 181.250 143.402 1.00 105.19 ? 872  SER A C   1 
ATOM   4971 O O   . SER A 1 750  ? 132.870 182.157 142.677 1.00 105.97 ? 872  SER A O   1 
ATOM   4972 C CB  . SER A 1 750  ? 134.837 182.503 144.909 1.00 100.12 ? 872  SER A CB  1 
ATOM   4973 O OG  . SER A 1 750  ? 135.946 181.916 144.259 1.00 104.71 ? 872  SER A OG  1 
ATOM   4974 N N   . GLN A 1 751  ? 133.495 179.984 142.991 1.00 103.73 ? 873  GLN A N   1 
ATOM   4975 C CA  . GLN A 1 751  ? 133.325 179.451 141.622 1.00 107.13 ? 873  GLN A CA  1 
ATOM   4976 C C   . GLN A 1 751  ? 134.148 180.205 140.576 1.00 107.86 ? 873  GLN A C   1 
ATOM   4977 O O   . GLN A 1 751  ? 133.685 180.445 139.459 1.00 110.44 ? 873  GLN A O   1 
ATOM   4978 C CB  . GLN A 1 751  ? 131.850 179.372 141.207 1.00 110.52 ? 873  GLN A CB  1 
ATOM   4979 C CG  . GLN A 1 751  ? 131.035 178.429 142.072 1.00 111.56 ? 873  GLN A CG  1 
ATOM   4980 C CD  . GLN A 1 751  ? 131.388 176.972 141.835 1.00 113.08 ? 873  GLN A CD  1 
ATOM   4981 O OE1 . GLN A 1 751  ? 131.725 176.576 140.719 1.00 112.81 ? 873  GLN A OE1 1 
ATOM   4982 N NE2 . GLN A 1 751  ? 131.320 176.168 142.888 1.00 107.71 ? 873  GLN A NE2 1 
ATOM   4983 N N   . SER A 1 752  ? 135.373 180.574 140.933 1.00 103.90 ? 874  SER A N   1 
ATOM   4984 C CA  . SER A 1 752  ? 136.319 181.191 140.015 1.00 99.54  ? 874  SER A CA  1 
ATOM   4985 C C   . SER A 1 752  ? 137.431 180.198 139.718 1.00 103.07 ? 874  SER A C   1 
ATOM   4986 O O   . SER A 1 752  ? 137.995 179.599 140.638 1.00 105.99 ? 874  SER A O   1 
ATOM   4987 C CB  . SER A 1 752  ? 136.904 182.476 140.601 1.00 93.12  ? 874  SER A CB  1 
ATOM   4988 O OG  . SER A 1 752  ? 135.880 183.339 141.058 1.00 99.09  ? 874  SER A OG  1 
ATOM   4989 N N   . ALA A 1 753  ? 137.742 180.024 138.439 1.00 104.89 ? 875  ALA A N   1 
ATOM   4990 C CA  . ALA A 1 753  ? 138.765 179.086 138.010 1.00 99.72  ? 875  ALA A CA  1 
ATOM   4991 C C   . ALA A 1 753  ? 139.909 179.831 137.343 1.00 96.88  ? 875  ALA A C   1 
ATOM   4992 O O   . ALA A 1 753  ? 139.687 180.680 136.474 1.00 94.55  ? 875  ALA A O   1 
ATOM   4993 C CB  . ALA A 1 753  ? 138.201 178.049 137.037 1.00 96.43  ? 875  ALA A CB  1 
ATOM   4994 N N   . PHE A 1 754  ? 141.128 179.512 137.756 1.00 97.59  ? 876  PHE A N   1 
ATOM   4995 C CA  . PHE A 1 754  ? 142.315 179.906 137.018 1.00 99.10  ? 876  PHE A CA  1 
ATOM   4996 C C   . PHE A 1 754  ? 142.975 178.635 136.511 1.00 99.45  ? 876  PHE A C   1 
ATOM   4997 O O   . PHE A 1 754  ? 143.048 177.632 137.226 1.00 99.96  ? 876  PHE A O   1 
ATOM   4998 C CB  . PHE A 1 754  ? 143.292 180.785 137.859 1.00 98.55  ? 876  PHE A CB  1 
ATOM   4999 C CG  . PHE A 1 754  ? 143.960 180.077 139.021 1.00 93.69  ? 876  PHE A CG  1 
ATOM   5000 C CD1 . PHE A 1 754  ? 143.296 179.932 140.242 1.00 94.33  ? 876  PHE A CD1 1 
ATOM   5001 C CD2 . PHE A 1 754  ? 145.279 179.619 138.907 1.00 88.80  ? 876  PHE A CD2 1 
ATOM   5002 C CE1 . PHE A 1 754  ? 143.914 179.298 141.318 1.00 96.35  ? 876  PHE A CE1 1 
ATOM   5003 C CE2 . PHE A 1 754  ? 145.906 178.982 139.974 1.00 90.86  ? 876  PHE A CE2 1 
ATOM   5004 C CZ  . PHE A 1 754  ? 145.222 178.829 141.181 1.00 95.84  ? 876  PHE A CZ  1 
ATOM   5005 N N   . SER A 1 755  ? 143.413 178.668 135.262 1.00 100.42 ? 877  SER A N   1 
ATOM   5006 C CA  . SER A 1 755  ? 143.964 177.501 134.596 1.00 95.80  ? 877  SER A CA  1 
ATOM   5007 C C   . SER A 1 755  ? 145.427 177.754 134.284 1.00 97.99  ? 877  SER A C   1 
ATOM   5008 O O   . SER A 1 755  ? 145.774 178.792 133.713 1.00 104.17 ? 877  SER A O   1 
ATOM   5009 C CB  . SER A 1 755  ? 143.187 177.190 133.316 1.00 107.53 ? 877  SER A CB  1 
ATOM   5010 O OG  . SER A 1 755  ? 143.736 176.073 132.649 1.00 108.64 ? 877  SER A OG  1 
ATOM   5011 N N   . ILE A 1 756  ? 146.280 176.813 134.668 1.00 94.66  ? 878  ILE A N   1 
ATOM   5012 C CA  . ILE A 1 756  ? 147.708 176.887 134.392 1.00 98.11  ? 878  ILE A CA  1 
ATOM   5013 C C   . ILE A 1 756  ? 148.035 175.894 133.281 1.00 101.27 ? 878  ILE A C   1 
ATOM   5014 O O   . ILE A 1 756  ? 147.351 174.875 133.118 1.00 103.76 ? 878  ILE A O   1 
ATOM   5015 C CB  . ILE A 1 756  ? 148.536 176.652 135.669 1.00 94.27  ? 878  ILE A CB  1 
ATOM   5016 C CG1 . ILE A 1 756  ? 148.289 175.266 136.258 1.00 96.71  ? 878  ILE A CG1 1 
ATOM   5017 C CG2 . ILE A 1 756  ? 148.227 177.721 136.703 1.00 99.69  ? 878  ILE A CG2 1 
ATOM   5018 C CD1 . ILE A 1 756  ? 149.208 174.908 137.336 1.00 99.67  ? 878  ILE A CD1 1 
ATOM   5019 N N   . ARG A 1 757  ? 149.016 176.231 132.456 1.00 104.73 ? 879  ARG A N   1 
ATOM   5020 C CA  . ARG A 1 757  ? 149.320 175.454 131.266 1.00 100.14 ? 879  ARG A CA  1 
ATOM   5021 C C   . ARG A 1 757  ? 150.818 175.212 131.168 1.00 102.32 ? 879  ARG A C   1 
ATOM   5022 O O   . ARG A 1 757  ? 151.600 175.716 131.981 1.00 107.95 ? 879  ARG A O   1 
ATOM   5023 C CB  . ARG A 1 757  ? 148.811 176.163 130.006 1.00 97.38  ? 879  ARG A CB  1 
ATOM   5024 C CG  . ARG A 1 757  ? 147.404 175.768 129.599 1.00 100.40 ? 879  ARG A CG  1 
ATOM   5025 C CD  . ARG A 1 757  ? 146.700 176.890 128.853 1.00 107.42 ? 879  ARG A CD  1 
ATOM   5026 N NE  . ARG A 1 757  ? 146.511 178.076 129.680 1.00 113.44 ? 879  ARG A NE  1 
ATOM   5027 C CZ  . ARG A 1 757  ? 145.499 178.922 129.551 1.00 114.51 ? 879  ARG A CZ  1 
ATOM   5028 N NH1 . ARG A 1 757  ? 144.563 178.747 128.632 1.00 113.76 ? 879  ARG A NH1 1 
ATOM   5029 N NH2 . ARG A 1 757  ? 145.425 179.974 130.362 1.00 108.77 ? 879  ARG A NH2 1 
ATOM   5030 N N   . ASN A 1 758  ? 151.181 174.426 130.143 1.00 97.29  ? 880  ASN A N   1 
ATOM   5031 C CA  . ASN A 1 758  ? 152.538 174.048 129.729 1.00 103.35 ? 880  ASN A CA  1 
ATOM   5032 C C   . ASN A 1 758  ? 153.343 173.364 130.824 1.00 96.55  ? 880  ASN A C   1 
ATOM   5033 O O   . ASN A 1 758  ? 154.546 173.621 130.962 1.00 97.05  ? 880  ASN A O   1 
ATOM   5034 C CB  . ASN A 1 758  ? 153.326 175.243 129.180 1.00 103.59 ? 880  ASN A CB  1 
ATOM   5035 C CG  . ASN A 1 758  ? 152.683 175.849 127.950 1.00 104.58 ? 880  ASN A CG  1 
ATOM   5036 O OD1 . ASN A 1 758  ? 152.675 177.066 127.779 1.00 109.46 ? 880  ASN A OD1 1 
ATOM   5037 N ND2 . ASN A 1 758  ? 152.139 175.000 127.085 1.00 100.10 ? 880  ASN A ND2 1 
ATOM   5038 N N   . ILE A 1 759  ? 152.708 172.500 131.616 1.00 86.74  ? 881  ILE A N   1 
ATOM   5039 C CA  . ILE A 1 759  ? 153.443 171.720 132.600 1.00 89.14  ? 881  ILE A CA  1 
ATOM   5040 C C   . ILE A 1 759  ? 154.146 170.567 131.900 1.00 96.62  ? 881  ILE A C   1 
ATOM   5041 O O   . ILE A 1 759  ? 153.501 169.680 131.329 1.00 102.73 ? 881  ILE A O   1 
ATOM   5042 C CB  . ILE A 1 759  ? 152.492 171.217 133.700 1.00 87.30  ? 881  ILE A CB  1 
ATOM   5043 C CG1 . ILE A 1 759  ? 151.712 172.383 134.303 1.00 86.41  ? 881  ILE A CG1 1 
ATOM   5044 C CG2 . ILE A 1 759  ? 153.268 170.503 134.781 1.00 89.26  ? 881  ILE A CG2 1 
ATOM   5045 C CD1 . ILE A 1 759  ? 150.522 171.956 135.118 1.00 85.49  ? 881  ILE A CD1 1 
ATOM   5046 N N   . ARG A 1 760  ? 155.478 170.573 131.944 1.00 96.79  ? 882  ARG A N   1 
ATOM   5047 C CA  . ARG A 1 760  ? 156.302 169.593 131.251 1.00 98.91  ? 882  ARG A CA  1 
ATOM   5048 C C   . ARG A 1 760  ? 156.275 168.214 131.896 1.00 99.56  ? 882  ARG A C   1 
ATOM   5049 O O   . ARG A 1 760  ? 156.581 167.225 131.221 1.00 103.88 ? 882  ARG A O   1 
ATOM   5050 C CB  . ARG A 1 760  ? 157.762 170.068 131.208 1.00 99.26  ? 882  ARG A CB  1 
ATOM   5051 C CG  . ARG A 1 760  ? 158.142 171.337 130.438 1.00 101.12 ? 882  ARG A CG  1 
ATOM   5052 C CD  . ARG A 1 760  ? 157.979 171.295 128.928 1.00 106.90 ? 882  ARG A CD  1 
ATOM   5053 N NE  . ARG A 1 760  ? 156.647 171.648 128.459 1.00 108.98 ? 882  ARG A NE  1 
ATOM   5054 C CZ  . ARG A 1 760  ? 156.217 171.451 127.222 1.00 112.04 ? 882  ARG A CZ  1 
ATOM   5055 N NH1 . ARG A 1 760  ? 156.962 170.823 126.325 1.00 112.92 ? 882  ARG A NH1 1 
ATOM   5056 N NH2 . ARG A 1 760  ? 155.042 171.956 126.863 1.00 111.04 ? 882  ARG A NH2 1 
ATOM   5057 N N   . GLY A 1 761  ? 155.907 168.112 133.171 1.00 96.78  ? 883  GLY A N   1 
ATOM   5058 C CA  . GLY A 1 761  ? 156.067 166.877 133.897 1.00 92.73  ? 883  GLY A CA  1 
ATOM   5059 C C   . GLY A 1 761  ? 154.808 166.391 134.587 1.00 96.09  ? 883  GLY A C   1 
ATOM   5060 O O   . GLY A 1 761  ? 153.764 167.052 134.560 1.00 98.50  ? 883  GLY A O   1 
ATOM   5061 N N   . PRO A 1 762  ? 154.888 165.215 135.239 1.00 97.65  ? 884  PRO A N   1 
ATOM   5062 C CA  . PRO A 1 762  ? 153.701 164.667 135.906 1.00 95.37  ? 884  PRO A CA  1 
ATOM   5063 C C   . PRO A 1 762  ? 153.515 165.160 137.335 1.00 94.35  ? 884  PRO A C   1 
ATOM   5064 O O   . PRO A 1 762  ? 152.610 164.698 138.037 1.00 95.93  ? 884  PRO A O   1 
ATOM   5065 C CB  . PRO A 1 762  ? 153.962 163.157 135.870 1.00 97.51  ? 884  PRO A CB  1 
ATOM   5066 C CG  . PRO A 1 762  ? 155.433 163.063 135.988 1.00 100.88 ? 884  PRO A CG  1 
ATOM   5067 C CD  . PRO A 1 762  ? 155.995 164.237 135.229 1.00 101.22 ? 884  PRO A CD  1 
ATOM   5068 N N   . ILE A 1 763  ? 154.363 166.080 137.790 1.00 93.77  ? 885  ILE A N   1 
ATOM   5069 C CA  . ILE A 1 763  ? 154.194 166.745 139.076 1.00 90.23  ? 885  ILE A CA  1 
ATOM   5070 C C   . ILE A 1 763  ? 154.091 168.243 138.827 1.00 90.65  ? 885  ILE A C   1 
ATOM   5071 O O   . ILE A 1 763  ? 154.520 168.735 137.777 1.00 92.70  ? 885  ILE A O   1 
ATOM   5072 C CB  . ILE A 1 763  ? 155.344 166.437 140.061 1.00 89.71  ? 885  ILE A CB  1 
ATOM   5073 C CG1 . ILE A 1 763  ? 156.697 166.897 139.515 1.00 91.28  ? 885  ILE A CG1 1 
ATOM   5074 C CG2 . ILE A 1 763  ? 155.398 164.955 140.400 1.00 93.45  ? 885  ILE A CG2 1 
ATOM   5075 C CD1 . ILE A 1 763  ? 157.806 166.848 140.534 1.00 94.19  ? 885  ILE A CD1 1 
ATOM   5076 N N   . PHE A 1 764  ? 153.482 168.956 139.770 1.00 85.04  ? 886  PHE A N   1 
ATOM   5077 C CA  . PHE A 1 764  ? 153.534 170.409 139.817 1.00 78.24  ? 886  PHE A CA  1 
ATOM   5078 C C   . PHE A 1 764  ? 153.412 170.846 141.267 1.00 81.91  ? 886  PHE A C   1 
ATOM   5079 O O   . PHE A 1 764  ? 152.731 170.191 142.060 1.00 83.63  ? 886  PHE A O   1 
ATOM   5080 C CB  . PHE A 1 764  ? 152.426 171.070 138.991 1.00 73.54  ? 886  PHE A CB  1 
ATOM   5081 C CG  . PHE A 1 764  ? 152.687 172.518 138.713 1.00 79.42  ? 886  PHE A CG  1 
ATOM   5082 C CD1 . PHE A 1 764  ? 153.634 172.883 137.758 1.00 89.87  ? 886  PHE A CD1 1 
ATOM   5083 C CD2 . PHE A 1 764  ? 152.042 173.513 139.448 1.00 77.58  ? 886  PHE A CD2 1 
ATOM   5084 C CE1 . PHE A 1 764  ? 153.908 174.226 137.504 1.00 85.27  ? 886  PHE A CE1 1 
ATOM   5085 C CE2 . PHE A 1 764  ? 152.324 174.861 139.219 1.00 76.35  ? 886  PHE A CE2 1 
ATOM   5086 C CZ  . PHE A 1 764  ? 153.246 175.212 138.236 1.00 75.09  ? 886  PHE A CZ  1 
ATOM   5087 N N   . GLY A 1 765  ? 154.074 171.944 141.608 1.00 79.99  ? 887  GLY A N   1 
ATOM   5088 C CA  . GLY A 1 765  ? 153.872 172.560 142.899 1.00 75.89  ? 887  GLY A CA  1 
ATOM   5089 C C   . GLY A 1 765  ? 153.127 173.871 142.778 1.00 79.29  ? 887  GLY A C   1 
ATOM   5090 O O   . GLY A 1 765  ? 153.664 174.838 142.230 1.00 86.98  ? 887  GLY A O   1 
ATOM   5091 N N   . LEU A 1 766  ? 151.885 173.906 143.254 1.00 75.65  ? 888  LEU A N   1 
ATOM   5092 C CA  . LEU A 1 766  ? 151.140 175.155 143.313 1.00 76.15  ? 888  LEU A CA  1 
ATOM   5093 C C   . LEU A 1 766  ? 151.696 176.053 144.406 1.00 84.24  ? 888  LEU A C   1 
ATOM   5094 O O   . LEU A 1 766  ? 152.238 175.577 145.404 1.00 89.18  ? 888  LEU A O   1 
ATOM   5095 C CB  . LEU A 1 766  ? 149.660 174.905 143.582 1.00 74.73  ? 888  LEU A CB  1 
ATOM   5096 C CG  . LEU A 1 766  ? 148.731 174.491 142.451 1.00 77.26  ? 888  LEU A CG  1 
ATOM   5097 C CD1 . LEU A 1 766  ? 147.315 174.501 142.975 1.00 81.11  ? 888  LEU A CD1 1 
ATOM   5098 C CD2 . LEU A 1 766  ? 148.867 175.435 141.278 1.00 83.76  ? 888  LEU A CD2 1 
ATOM   5099 N N   . GLN A 1 767  ? 151.567 177.358 144.203 1.00 80.78  ? 889  GLN A N   1 
ATOM   5100 C CA  . GLN A 1 767  ? 151.979 178.346 145.184 1.00 81.71  ? 889  GLN A CA  1 
ATOM   5101 C C   . GLN A 1 767  ? 150.941 179.455 145.213 1.00 80.35  ? 889  GLN A C   1 
ATOM   5102 O O   . GLN A 1 767  ? 150.082 179.536 144.329 1.00 86.34  ? 889  GLN A O   1 
ATOM   5103 C CB  . GLN A 1 767  ? 153.368 178.918 144.871 1.00 84.70  ? 889  GLN A CB  1 
ATOM   5104 C CG  . GLN A 1 767  ? 154.520 178.062 145.366 1.00 91.62  ? 889  GLN A CG  1 
ATOM   5105 C CD  . GLN A 1 767  ? 155.856 178.527 144.838 1.00 106.51 ? 889  GLN A CD  1 
ATOM   5106 O OE1 . GLN A 1 767  ? 156.140 179.724 144.799 1.00 114.42 ? 889  GLN A OE1 1 
ATOM   5107 N NE2 . GLN A 1 767  ? 156.690 177.579 144.428 1.00 104.64 ? 889  GLN A NE2 1 
ATOM   5108 N N   . ARG A 1 768  ? 151.053 180.292 146.258 1.00 79.83  ? 890  ARG A N   1 
ATOM   5109 C CA  . ARG A 1 768  ? 150.229 181.483 146.536 1.00 79.18  ? 890  ARG A CA  1 
ATOM   5110 C C   . ARG A 1 768  ? 148.736 181.169 146.635 1.00 81.54  ? 890  ARG A C   1 
ATOM   5111 O O   . ARG A 1 768  ? 147.898 181.918 146.129 1.00 82.50  ? 890  ARG A O   1 
ATOM   5112 C CB  . ARG A 1 768  ? 150.485 182.604 145.518 1.00 84.06  ? 890  ARG A CB  1 
ATOM   5113 C CG  . ARG A 1 768  ? 151.943 183.044 145.444 1.00 90.86  ? 890  ARG A CG  1 
ATOM   5114 C CD  . ARG A 1 768  ? 152.310 183.616 144.081 1.00 100.00 ? 890  ARG A CD  1 
ATOM   5115 N NE  . ARG A 1 768  ? 152.465 182.584 143.062 1.00 104.04 ? 890  ARG A NE  1 
ATOM   5116 C CZ  . ARG A 1 768  ? 151.595 182.351 142.089 1.00 106.89 ? 890  ARG A CZ  1 
ATOM   5117 N NH1 . ARG A 1 768  ? 150.491 183.069 141.963 1.00 101.33 ? 890  ARG A NH1 1 
ATOM   5118 N NH2 . ARG A 1 768  ? 151.838 181.373 141.222 1.00 105.10 ? 890  ARG A NH2 1 
ATOM   5119 N N   . LEU A 1 769  ? 148.399 180.058 147.283 1.00 82.55  ? 891  LEU A N   1 
ATOM   5120 C CA  . LEU A 1 769  ? 147.015 179.689 147.525 1.00 74.00  ? 891  LEU A CA  1 
ATOM   5121 C C   . LEU A 1 769  ? 146.463 180.452 148.725 1.00 81.25  ? 891  LEU A C   1 
ATOM   5122 O O   . LEU A 1 769  ? 147.181 181.160 149.435 1.00 88.21  ? 891  LEU A O   1 
ATOM   5123 C CB  . LEU A 1 769  ? 146.892 178.185 147.764 1.00 69.05  ? 891  LEU A CB  1 
ATOM   5124 C CG  . LEU A 1 769  ? 147.043 177.254 146.563 1.00 75.19  ? 891  LEU A CG  1 
ATOM   5125 C CD1 . LEU A 1 769  ? 146.825 175.819 146.987 1.00 67.42  ? 891  LEU A CD1 1 
ATOM   5126 C CD2 . LEU A 1 769  ? 146.071 177.632 145.463 1.00 80.94  ? 891  LEU A CD2 1 
ATOM   5127 N N   . GLN A 1 770  ? 145.165 180.299 148.949 1.00 82.13  ? 892  GLN A N   1 
ATOM   5128 C CA  . GLN A 1 770  ? 144.546 180.932 150.097 1.00 84.86  ? 892  GLN A CA  1 
ATOM   5129 C C   . GLN A 1 770  ? 144.391 179.928 151.234 1.00 82.70  ? 892  GLN A C   1 
ATOM   5130 O O   . GLN A 1 770  ? 144.053 178.767 150.981 1.00 83.57  ? 892  GLN A O   1 
ATOM   5131 C CB  . GLN A 1 770  ? 143.177 181.515 149.734 1.00 87.35  ? 892  GLN A CB  1 
ATOM   5132 C CG  . GLN A 1 770  ? 143.230 182.999 149.415 1.00 96.01  ? 892  GLN A CG  1 
ATOM   5133 C CD  . GLN A 1 770  ? 141.862 183.644 149.394 1.00 108.15 ? 892  GLN A CD  1 
ATOM   5134 O OE1 . GLN A 1 770  ? 140.840 182.959 149.399 1.00 114.19 ? 892  GLN A OE1 1 
ATOM   5135 N NE2 . GLN A 1 770  ? 141.834 184.971 149.368 1.00 101.21 ? 892  GLN A NE2 1 
ATOM   5136 N N   . PRO A 1 771  ? 144.652 180.325 152.483 1.00 76.59  ? 893  PRO A N   1 
ATOM   5137 C CA  . PRO A 1 771  ? 144.604 179.354 153.581 1.00 73.01  ? 893  PRO A CA  1 
ATOM   5138 C C   . PRO A 1 771  ? 143.177 179.071 154.029 1.00 79.97  ? 893  PRO A C   1 
ATOM   5139 O O   . PRO A 1 771  ? 142.319 179.961 154.003 1.00 87.54  ? 893  PRO A O   1 
ATOM   5140 C CB  . PRO A 1 771  ? 145.423 180.031 154.683 1.00 77.24  ? 893  PRO A CB  1 
ATOM   5141 C CG  . PRO A 1 771  ? 145.266 181.476 154.418 1.00 76.08  ? 893  PRO A CG  1 
ATOM   5142 C CD  . PRO A 1 771  ? 145.208 181.617 152.931 1.00 74.82  ? 893  PRO A CD  1 
ATOM   5143 N N   . ASP A 1 772  ? 142.957 177.805 154.426 1.00 78.10  ? 894  ASP A N   1 
ATOM   5144 C CA  . ASP A 1 772  ? 141.690 177.224 154.911 1.00 79.34  ? 894  ASP A CA  1 
ATOM   5145 C C   . ASP A 1 772  ? 140.556 177.385 153.897 1.00 86.90  ? 894  ASP A C   1 
ATOM   5146 O O   . ASP A 1 772  ? 139.456 177.839 154.218 1.00 94.63  ? 894  ASP A O   1 
ATOM   5147 C CB  . ASP A 1 772  ? 141.300 177.789 156.283 1.00 85.82  ? 894  ASP A CB  1 
ATOM   5148 C CG  . ASP A 1 772  ? 140.442 176.833 157.088 1.00 94.73  ? 894  ASP A CG  1 
ATOM   5149 O OD1 . ASP A 1 772  ? 140.229 175.691 156.631 1.00 98.40  ? 894  ASP A OD1 1 
ATOM   5150 O OD2 . ASP A 1 772  ? 139.983 177.226 158.180 1.00 91.79  ? 894  ASP A OD2 1 
ATOM   5151 N N   . ASN A 1 773  ? 140.840 177.023 152.649 1.00 82.52  ? 895  ASN A N   1 
ATOM   5152 C CA  . ASN A 1 773  ? 139.886 177.185 151.566 1.00 81.81  ? 895  ASN A CA  1 
ATOM   5153 C C   . ASN A 1 773  ? 139.856 175.874 150.795 1.00 82.48  ? 895  ASN A C   1 
ATOM   5154 O O   . ASN A 1 773  ? 140.887 175.218 150.631 1.00 86.52  ? 895  ASN A O   1 
ATOM   5155 C CB  . ASN A 1 773  ? 140.292 178.371 150.661 1.00 84.92  ? 895  ASN A CB  1 
ATOM   5156 C CG  . ASN A 1 773  ? 139.222 178.764 149.629 1.00 95.37  ? 895  ASN A CG  1 
ATOM   5157 O OD1 . ASN A 1 773  ? 138.149 178.167 149.525 1.00 96.14  ? 895  ASN A OD1 1 
ATOM   5158 N ND2 . ASN A 1 773  ? 139.532 179.796 148.856 1.00 95.03  ? 895  ASN A ND2 1 
ATOM   5159 N N   . LEU A 1 774  ? 138.671 175.502 150.324 1.00 80.29  ? 896  LEU A N   1 
ATOM   5160 C CA  . LEU A 1 774  ? 138.481 174.259 149.590 1.00 82.89  ? 896  LEU A CA  1 
ATOM   5161 C C   . LEU A 1 774  ? 138.700 174.511 148.105 1.00 88.65  ? 896  LEU A C   1 
ATOM   5162 O O   . LEU A 1 774  ? 138.205 175.499 147.558 1.00 92.87  ? 896  LEU A O   1 
ATOM   5163 C CB  . LEU A 1 774  ? 137.078 173.703 149.839 1.00 87.19  ? 896  LEU A CB  1 
ATOM   5164 C CG  . LEU A 1 774  ? 136.704 172.360 149.208 1.00 88.49  ? 896  LEU A CG  1 
ATOM   5165 C CD1 . LEU A 1 774  ? 137.582 171.248 149.742 1.00 89.63  ? 896  LEU A CD1 1 
ATOM   5166 C CD2 . LEU A 1 774  ? 135.237 172.046 149.437 1.00 92.64  ? 896  LEU A CD2 1 
ATOM   5167 N N   . TYR A 1 775  ? 139.448 173.618 147.460 1.00 91.74  ? 897  TYR A N   1 
ATOM   5168 C CA  . TYR A 1 775  ? 139.807 173.756 146.058 1.00 85.48  ? 897  TYR A CA  1 
ATOM   5169 C C   . TYR A 1 775  ? 139.425 172.490 145.308 1.00 89.06  ? 897  TYR A C   1 
ATOM   5170 O O   . TYR A 1 775  ? 139.440 171.393 145.864 1.00 92.03  ? 897  TYR A O   1 
ATOM   5171 C CB  . TYR A 1 775  ? 141.306 174.022 145.888 1.00 79.54  ? 897  TYR A CB  1 
ATOM   5172 C CG  . TYR A 1 775  ? 141.714 175.442 146.176 1.00 75.75  ? 897  TYR A CG  1 
ATOM   5173 C CD1 . TYR A 1 775  ? 141.377 176.471 145.295 1.00 82.72  ? 897  TYR A CD1 1 
ATOM   5174 C CD2 . TYR A 1 775  ? 142.436 175.755 147.332 1.00 73.02  ? 897  TYR A CD2 1 
ATOM   5175 C CE1 . TYR A 1 775  ? 141.750 177.784 145.554 1.00 82.12  ? 897  TYR A CE1 1 
ATOM   5176 C CE2 . TYR A 1 775  ? 142.812 177.065 147.604 1.00 78.90  ? 897  TYR A CE2 1 
ATOM   5177 C CZ  . TYR A 1 775  ? 142.465 178.068 146.708 1.00 79.30  ? 897  TYR A CZ  1 
ATOM   5178 O OH  . TYR A 1 775  ? 142.832 179.365 146.964 1.00 82.42  ? 897  TYR A OH  1 
ATOM   5179 N N   . GLN A 1 776  ? 139.091 172.652 144.032 1.00 86.01  ? 898  GLN A N   1 
ATOM   5180 C CA  . GLN A 1 776  ? 138.719 171.543 143.163 1.00 86.17  ? 898  GLN A CA  1 
ATOM   5181 C C   . GLN A 1 776  ? 139.704 171.468 142.005 1.00 87.14  ? 898  GLN A C   1 
ATOM   5182 O O   . GLN A 1 776  ? 139.889 172.451 141.281 1.00 88.42  ? 898  GLN A O   1 
ATOM   5183 C CB  . GLN A 1 776  ? 137.286 171.718 142.658 1.00 92.94  ? 898  GLN A CB  1 
ATOM   5184 C CG  . GLN A 1 776  ? 136.756 170.560 141.842 1.00 103.26 ? 898  GLN A CG  1 
ATOM   5185 C CD  . GLN A 1 776  ? 135.275 170.688 141.559 1.00 110.76 ? 898  GLN A CD  1 
ATOM   5186 O OE1 . GLN A 1 776  ? 134.620 171.615 142.033 1.00 111.55 ? 898  GLN A OE1 1 
ATOM   5187 N NE2 . GLN A 1 776  ? 134.737 169.760 140.779 1.00 110.17 ? 898  GLN A NE2 1 
ATOM   5188 N N   . LEU A 1 777  ? 140.329 170.305 141.826 1.00 86.99  ? 899  LEU A N   1 
ATOM   5189 C CA  . LEU A 1 777  ? 141.485 170.156 140.949 1.00 82.19  ? 899  LEU A CA  1 
ATOM   5190 C C   . LEU A 1 777  ? 141.214 169.105 139.882 1.00 90.31  ? 899  LEU A C   1 
ATOM   5191 O O   . LEU A 1 777  ? 140.916 167.951 140.207 1.00 96.54  ? 899  LEU A O   1 
ATOM   5192 C CB  . LEU A 1 777  ? 142.726 169.770 141.754 1.00 82.01  ? 899  LEU A CB  1 
ATOM   5193 C CG  . LEU A 1 777  ? 143.158 170.715 142.872 1.00 80.89  ? 899  LEU A CG  1 
ATOM   5194 C CD1 . LEU A 1 777  ? 143.939 169.956 143.926 1.00 79.99  ? 899  LEU A CD1 1 
ATOM   5195 C CD2 . LEU A 1 777  ? 143.981 171.857 142.315 1.00 85.28  ? 899  LEU A CD2 1 
ATOM   5196 N N   . ARG A 1 778  ? 141.330 169.501 138.613 1.00 87.08  ? 900  ARG A N   1 
ATOM   5197 C CA  . ARG A 1 778  ? 141.297 168.594 137.472 1.00 82.00  ? 900  ARG A CA  1 
ATOM   5198 C C   . ARG A 1 778  ? 142.532 168.829 136.611 1.00 91.40  ? 900  ARG A C   1 
ATOM   5199 O O   . ARG A 1 778  ? 143.073 169.936 136.573 1.00 96.58  ? 900  ARG A O   1 
ATOM   5200 C CB  . ARG A 1 778  ? 140.044 168.792 136.600 1.00 86.91  ? 900  ARG A CB  1 
ATOM   5201 C CG  . ARG A 1 778  ? 138.731 168.975 137.329 1.00 91.53  ? 900  ARG A CG  1 
ATOM   5202 C CD  . ARG A 1 778  ? 137.557 168.856 136.382 1.00 92.56  ? 900  ARG A CD  1 
ATOM   5203 N NE  . ARG A 1 778  ? 137.537 169.926 135.396 1.00 99.14  ? 900  ARG A NE  1 
ATOM   5204 C CZ  . ARG A 1 778  ? 136.798 169.913 134.296 1.00 101.23 ? 900  ARG A CZ  1 
ATOM   5205 N NH1 . ARG A 1 778  ? 136.018 168.887 134.001 1.00 101.58 ? 900  ARG A NH1 1 
ATOM   5206 N NH2 . ARG A 1 778  ? 136.842 170.955 133.472 1.00 96.13  ? 900  ARG A NH2 1 
ATOM   5207 N N   . VAL A 1 779  ? 142.974 167.785 135.909 1.00 91.27  ? 901  VAL A N   1 
ATOM   5208 C CA  . VAL A 1 779  ? 144.130 167.875 135.024 1.00 84.76  ? 901  VAL A CA  1 
ATOM   5209 C C   . VAL A 1 779  ? 143.775 167.184 133.706 1.00 91.13  ? 901  VAL A C   1 
ATOM   5210 O O   . VAL A 1 779  ? 142.864 166.353 133.647 1.00 99.73  ? 901  VAL A O   1 
ATOM   5211 C CB  . VAL A 1 779  ? 145.399 167.281 135.710 1.00 82.90  ? 901  VAL A CB  1 
ATOM   5212 C CG1 . VAL A 1 779  ? 145.414 165.754 135.731 1.00 86.81  ? 901  VAL A CG1 1 
ATOM   5213 C CG2 . VAL A 1 779  ? 146.704 167.875 135.168 1.00 87.30  ? 901  VAL A CG2 1 
ATOM   5214 N N   . ARG A 1 780  ? 144.436 167.597 132.625 1.00 94.17  ? 902  ARG A N   1 
ATOM   5215 C CA  . ARG A 1 780  ? 144.247 166.997 131.310 1.00 95.11  ? 902  ARG A CA  1 
ATOM   5216 C C   . ARG A 1 780  ? 145.573 167.010 130.566 1.00 99.04  ? 902  ARG A C   1 
ATOM   5217 O O   . ARG A 1 780  ? 146.519 167.683 130.971 1.00 105.24 ? 902  ARG A O   1 
ATOM   5218 C CB  . ARG A 1 780  ? 143.162 167.721 130.501 1.00 93.42  ? 902  ARG A CB  1 
ATOM   5219 C CG  . ARG A 1 780  ? 143.592 169.032 129.877 1.00 91.54  ? 902  ARG A CG  1 
ATOM   5220 C CD  . ARG A 1 780  ? 142.494 169.564 128.982 1.00 100.69 ? 902  ARG A CD  1 
ATOM   5221 N NE  . ARG A 1 780  ? 142.651 170.981 128.680 1.00 101.60 ? 902  ARG A NE  1 
ATOM   5222 C CZ  . ARG A 1 780  ? 141.694 171.740 128.166 1.00 105.15 ? 902  ARG A CZ  1 
ATOM   5223 N NH1 . ARG A 1 780  ? 140.493 171.253 127.906 1.00 100.20 ? 902  ARG A NH1 1 
ATOM   5224 N NH2 . ARG A 1 780  ? 141.951 173.016 127.897 1.00 104.63 ? 902  ARG A NH2 1 
ATOM   5225 N N   . ALA A 1 781  ? 145.639 166.248 129.478 1.00 98.60  ? 903  ALA A N   1 
ATOM   5226 C CA  . ALA A 1 781  ? 146.866 166.088 128.706 1.00 97.50  ? 903  ALA A CA  1 
ATOM   5227 C C   . ALA A 1 781  ? 146.762 166.849 127.392 1.00 102.50 ? 903  ALA A C   1 
ATOM   5228 O O   . ALA A 1 781  ? 145.747 166.755 126.692 1.00 110.99 ? 903  ALA A O   1 
ATOM   5229 C CB  . ALA A 1 781  ? 147.156 164.612 128.436 1.00 100.85 ? 903  ALA A CB  1 
ATOM   5230 N N   . ILE A 1 782  ? 147.806 167.618 127.094 1.00 99.68  ? 904  ILE A N   1 
ATOM   5231 C CA  . ILE A 1 782  ? 147.855 168.363 125.808 1.00 108.23 ? 904  ILE A CA  1 
ATOM   5232 C C   . ILE A 1 782  ? 148.948 167.710 124.956 1.00 112.80 ? 904  ILE A C   1 
ATOM   5233 O O   . ILE A 1 782  ? 150.101 167.702 125.401 1.00 111.77 ? 904  ILE A O   1 
ATOM   5234 C CB  . ILE A 1 782  ? 148.109 169.857 126.075 1.00 103.84 ? 904  ILE A CB  1 
ATOM   5235 C CG1 . ILE A 1 782  ? 146.977 170.482 126.894 1.00 103.82 ? 904  ILE A CG1 1 
ATOM   5236 C CG2 . ILE A 1 782  ? 148.344 170.612 124.781 1.00 106.73 ? 904  ILE A CG2 1 
ATOM   5237 C CD1 . ILE A 1 782  ? 147.124 171.969 127.096 1.00 103.24 ? 904  ILE A CD1 1 
ATOM   5238 N N   . ASN A 1 783  ? 148.599 167.191 123.776 1.00 117.74 ? 905  ASN A N   1 
ATOM   5239 C CA  . ASN A 1 783  ? 149.565 166.463 122.906 1.00 118.61 ? 905  ASN A CA  1 
ATOM   5240 C C   . ASN A 1 783  ? 150.492 167.449 122.196 1.00 122.05 ? 905  ASN A C   1 
ATOM   5241 O O   . ASN A 1 783  ? 150.307 168.660 122.374 1.00 123.32 ? 905  ASN A O   1 
ATOM   5242 C CB  . ASN A 1 783  ? 148.862 165.536 121.915 1.00 115.10 ? 905  ASN A CB  1 
ATOM   5243 C CG  . ASN A 1 783  ? 147.721 166.194 121.173 1.00 117.83 ? 905  ASN A CG  1 
ATOM   5244 O OD1 . ASN A 1 783  ? 147.873 167.281 120.624 1.00 119.71 ? 905  ASN A OD1 1 
ATOM   5245 N ND2 . ASN A 1 783  ? 146.578 165.533 121.138 1.00 113.98 ? 905  ASN A ND2 1 
ATOM   5246 N N   . VAL A 1 784  ? 151.464 166.948 121.434 1.00 120.65 ? 906  VAL A N   1 
ATOM   5247 C CA  . VAL A 1 784  ? 152.466 167.849 120.789 1.00 121.12 ? 906  VAL A CA  1 
ATOM   5248 C C   . VAL A 1 784  ? 151.738 168.817 119.855 1.00 120.74 ? 906  VAL A C   1 
ATOM   5249 O O   . VAL A 1 784  ? 152.169 169.979 119.761 1.00 118.07 ? 906  VAL A O   1 
ATOM   5250 C CB  . VAL A 1 784  ? 153.567 167.044 120.075 1.00 121.23 ? 906  VAL A CB  1 
ATOM   5251 C CG1 . VAL A 1 784  ? 152.999 166.046 119.081 1.00 118.10 ? 906  VAL A CG1 1 
ATOM   5252 C CG2 . VAL A 1 784  ? 154.605 167.939 119.416 1.00 121.66 ? 906  VAL A CG2 1 
ATOM   5253 N N   . ASP A 1 785  ? 150.659 168.368 119.216 1.00 121.27 ? 907  ASP A N   1 
ATOM   5254 C CA  . ASP A 1 785  ? 149.857 169.249 118.326 1.00 125.16 ? 907  ASP A CA  1 
ATOM   5255 C C   . ASP A 1 785  ? 149.229 170.374 119.148 1.00 124.21 ? 907  ASP A C   1 
ATOM   5256 O O   . ASP A 1 785  ? 149.030 171.464 118.586 1.00 126.55 ? 907  ASP A O   1 
ATOM   5257 C CB  . ASP A 1 785  ? 148.816 168.462 117.532 1.00 126.16 ? 907  ASP A CB  1 
ATOM   5258 C CG  . ASP A 1 785  ? 149.406 167.725 116.342 1.00 129.27 ? 907  ASP A CG  1 
ATOM   5259 O OD1 . ASP A 1 785  ? 148.618 167.218 115.520 1.00 130.26 ? 907  ASP A OD1 1 
ATOM   5260 O OD2 . ASP A 1 785  ? 150.647 167.662 116.250 1.00 126.38 ? 907  ASP A OD2 1 
ATOM   5261 N N   . GLY A 1 786  ? 148.928 170.120 120.420 1.00 120.72 ? 908  GLY A N   1 
ATOM   5262 C CA  . GLY A 1 786  ? 148.246 171.129 121.252 1.00 119.23 ? 908  GLY A CA  1 
ATOM   5263 C C   . GLY A 1 786  ? 146.770 170.824 121.368 1.00 117.25 ? 908  GLY A C   1 
ATOM   5264 O O   . GLY A 1 786  ? 146.045 171.627 121.974 1.00 114.34 ? 908  GLY A O   1 
ATOM   5265 N N   . GLU A 1 787  ? 146.349 169.691 120.818 1.00 119.17 ? 909  GLU A N   1 
ATOM   5266 C CA  . GLU A 1 787  ? 144.931 169.276 120.931 1.00 122.47 ? 909  GLU A CA  1 
ATOM   5267 C C   . GLU A 1 787  ? 144.684 168.808 122.372 1.00 117.20 ? 909  GLU A C   1 
ATOM   5268 O O   . GLU A 1 787  ? 145.380 167.866 122.785 1.00 113.03 ? 909  GLU A O   1 
ATOM   5269 C CB  . GLU A 1 787  ? 144.619 168.185 119.905 1.00 123.18 ? 909  GLU A CB  1 
ATOM   5270 C CG  . GLU A 1 787  ? 143.250 167.554 120.078 1.00 126.89 ? 909  GLU A CG  1 
ATOM   5271 C CD  . GLU A 1 787  ? 142.073 168.470 119.785 1.00 132.14 ? 909  GLU A CD  1 
ATOM   5272 O OE1 . GLU A 1 787  ? 142.231 169.388 118.957 1.00 134.54 ? 909  GLU A OE1 1 
ATOM   5273 O OE2 . GLU A 1 787  ? 141.004 168.264 120.391 1.00 129.23 ? 909  GLU A OE2 1 
ATOM   5274 N N   . PRO A 1 788  ? 143.766 169.394 123.182 1.00 115.90 ? 910  PRO A N   1 
ATOM   5275 C CA  . PRO A 1 788  ? 143.614 168.922 124.559 1.00 112.18 ? 910  PRO A CA  1 
ATOM   5276 C C   . PRO A 1 788  ? 142.884 167.590 124.641 1.00 113.30 ? 910  PRO A C   1 
ATOM   5277 O O   . PRO A 1 788  ? 142.118 167.206 123.755 1.00 118.28 ? 910  PRO A O   1 
ATOM   5278 C CB  . PRO A 1 788  ? 142.791 170.031 125.215 1.00 113.80 ? 910  PRO A CB  1 
ATOM   5279 C CG  . PRO A 1 788  ? 141.973 170.573 124.110 1.00 115.61 ? 910  PRO A CG  1 
ATOM   5280 C CD  . PRO A 1 788  ? 142.843 170.507 122.886 1.00 116.15 ? 910  PRO A CD  1 
ATOM   5281 N N   . GLY A 1 789  ? 143.142 166.887 125.731 1.00 109.29 ? 911  GLY A N   1 
ATOM   5282 C CA  . GLY A 1 789  ? 142.520 165.609 126.008 1.00 107.79 ? 911  GLY A CA  1 
ATOM   5283 C C   . GLY A 1 789  ? 141.268 165.759 126.844 1.00 112.54 ? 911  GLY A C   1 
ATOM   5284 O O   . GLY A 1 789  ? 140.587 166.790 126.802 1.00 113.65 ? 911  GLY A O   1 
ATOM   5285 N N   . GLU A 1 790  ? 140.963 164.722 127.614 1.00 112.07 ? 912  GLU A N   1 
ATOM   5286 C CA  . GLU A 1 790  ? 139.795 164.691 128.477 1.00 114.94 ? 912  GLU A CA  1 
ATOM   5287 C C   . GLU A 1 790  ? 140.240 164.942 129.911 1.00 113.88 ? 912  GLU A C   1 
ATOM   5288 O O   . GLU A 1 790  ? 141.298 164.457 130.328 1.00 111.09 ? 912  GLU A O   1 
ATOM   5289 C CB  . GLU A 1 790  ? 139.069 163.341 128.347 1.00 119.08 ? 912  GLU A CB  1 
ATOM   5290 C CG  . GLU A 1 790  ? 137.753 163.195 129.115 1.00 122.98 ? 912  GLU A CG  1 
ATOM   5291 C CD  . GLU A 1 790  ? 136.632 164.071 128.573 1.00 128.74 ? 912  GLU A CD  1 
ATOM   5292 O OE1 . GLU A 1 790  ? 136.622 164.370 127.360 1.00 125.73 ? 912  GLU A OE1 1 
ATOM   5293 O OE2 . GLU A 1 790  ? 135.753 164.464 129.370 1.00 130.39 ? 912  GLU A OE2 1 
ATOM   5294 N N   . TRP A 1 791  ? 139.455 165.737 130.641 1.00 109.98 ? 913  TRP A N   1 
ATOM   5295 C CA  . TRP A 1 791  ? 139.765 166.093 132.020 1.00 102.90 ? 913  TRP A CA  1 
ATOM   5296 C C   . TRP A 1 791  ? 139.615 164.900 132.959 1.00 102.94 ? 913  TRP A C   1 
ATOM   5297 O O   . TRP A 1 791  ? 138.781 164.013 132.754 1.00 110.03 ? 913  TRP A O   1 
ATOM   5298 C CB  . TRP A 1 791  ? 138.853 167.219 132.506 1.00 95.61  ? 913  TRP A CB  1 
ATOM   5299 C CG  . TRP A 1 791  ? 139.101 168.568 131.903 1.00 99.12  ? 913  TRP A CG  1 
ATOM   5300 C CD1 . TRP A 1 791  ? 138.366 169.173 130.929 1.00 104.60 ? 913  TRP A CD1 1 
ATOM   5301 C CD2 . TRP A 1 791  ? 140.128 169.499 132.265 1.00 98.06  ? 913  TRP A CD2 1 
ATOM   5302 N NE1 . TRP A 1 791  ? 138.881 170.415 130.646 1.00 102.37 ? 913  TRP A NE1 1 
ATOM   5303 C CE2 . TRP A 1 791  ? 139.963 170.639 131.454 1.00 98.71  ? 913  TRP A CE2 1 
ATOM   5304 C CE3 . TRP A 1 791  ? 141.178 169.474 133.188 1.00 94.85  ? 913  TRP A CE3 1 
ATOM   5305 C CZ2 . TRP A 1 791  ? 140.806 171.747 131.543 1.00 96.52  ? 913  TRP A CZ2 1 
ATOM   5306 C CZ3 . TRP A 1 791  ? 142.017 170.574 133.274 1.00 93.68  ? 913  TRP A CZ3 1 
ATOM   5307 C CH2 . TRP A 1 791  ? 141.827 171.693 132.454 1.00 94.06  ? 913  TRP A CH2 1 
ATOM   5308 N N   . THR A 1 792  ? 140.442 164.892 133.997 1.00 97.11  ? 914  THR A N   1 
ATOM   5309 C CA  . THR A 1 792  ? 140.405 163.918 135.073 1.00 100.26 ? 914  THR A CA  1 
ATOM   5310 C C   . THR A 1 792  ? 139.180 164.218 135.951 1.00 102.72 ? 914  THR A C   1 
ATOM   5311 O O   . THR A 1 792  ? 138.695 165.355 135.993 1.00 100.31 ? 914  THR A O   1 
ATOM   5312 C CB  . THR A 1 792  ? 141.755 163.986 135.818 1.00 95.56  ? 914  THR A CB  1 
ATOM   5313 O OG1 . THR A 1 792  ? 142.800 163.766 134.867 1.00 100.51 ? 914  THR A OG1 1 
ATOM   5314 C CG2 . THR A 1 792  ? 141.956 162.912 136.899 1.00 95.49  ? 914  THR A CG2 1 
ATOM   5315 N N   . GLU A 1 793  ? 138.604 163.157 136.547 1.00 106.24 ? 915  GLU A N   1 
ATOM   5316 C CA  . GLU A 1 793  ? 137.598 163.279 137.597 1.00 110.24 ? 915  GLU A CA  1 
ATOM   5317 C C   . GLU A 1 793  ? 138.158 164.067 138.783 1.00 108.58 ? 915  GLU A C   1 
ATOM   5318 O O   . GLU A 1 793  ? 139.291 163.814 139.206 1.00 108.20 ? 915  GLU A O   1 
ATOM   5319 C CB  . GLU A 1 793  ? 137.159 161.888 138.061 1.00 114.95 ? 915  GLU A CB  1 
ATOM   5320 C CG  . GLU A 1 793  ? 136.000 161.281 137.282 1.00 123.96 ? 915  GLU A CG  1 
ATOM   5321 C CD  . GLU A 1 793  ? 134.796 162.195 137.196 1.00 128.37 ? 915  GLU A CD  1 
ATOM   5322 O OE1 . GLU A 1 793  ? 134.378 162.527 136.067 1.00 130.17 ? 915  GLU A OE1 1 
ATOM   5323 O OE2 . GLU A 1 793  ? 134.254 162.565 138.258 1.00 121.74 ? 915  GLU A OE2 1 
ATOM   5324 N N   . PRO A 1 794  ? 137.410 165.047 139.309 1.00 103.91 ? 916  PRO A N   1 
ATOM   5325 C CA  . PRO A 1 794  ? 138.024 166.085 140.149 1.00 99.92  ? 916  PRO A CA  1 
ATOM   5326 C C   . PRO A 1 794  ? 138.328 165.648 141.573 1.00 102.11 ? 916  PRO A C   1 
ATOM   5327 O O   . PRO A 1 794  ? 137.598 164.864 142.184 1.00 104.95 ? 916  PRO A O   1 
ATOM   5328 C CB  . PRO A 1 794  ? 136.972 167.199 140.146 1.00 95.42  ? 916  PRO A CB  1 
ATOM   5329 C CG  . PRO A 1 794  ? 135.699 166.510 139.922 1.00 95.76  ? 916  PRO A CG  1 
ATOM   5330 C CD  . PRO A 1 794  ? 135.995 165.352 139.026 1.00 101.30 ? 916  PRO A CD  1 
ATOM   5331 N N   . LEU A 1 795  ? 139.436 166.169 142.089 1.00 99.48  ? 917  LEU A N   1 
ATOM   5332 C CA  . LEU A 1 795  ? 139.834 165.962 143.470 1.00 96.84  ? 917  LEU A CA  1 
ATOM   5333 C C   . LEU A 1 795  ? 139.529 167.226 144.261 1.00 94.50  ? 917  LEU A C   1 
ATOM   5334 O O   . LEU A 1 795  ? 139.916 168.326 143.857 1.00 97.78  ? 917  LEU A O   1 
ATOM   5335 C CB  . LEU A 1 795  ? 141.320 165.595 143.546 1.00 90.34  ? 917  LEU A CB  1 
ATOM   5336 C CG  . LEU A 1 795  ? 142.009 165.179 144.851 1.00 92.70  ? 917  LEU A CG  1 
ATOM   5337 C CD1 . LEU A 1 795  ? 143.020 164.126 144.535 1.00 85.94  ? 917  LEU A CD1 1 
ATOM   5338 C CD2 . LEU A 1 795  ? 142.748 166.327 145.515 1.00 97.19  ? 917  LEU A CD2 1 
ATOM   5339 N N   . ALA A 1 796  ? 138.838 167.066 145.382 1.00 89.42  ? 918  ALA A N   1 
ATOM   5340 C CA  . ALA A 1 796  ? 138.513 168.171 146.268 1.00 89.43  ? 918  ALA A CA  1 
ATOM   5341 C C   . ALA A 1 796  ? 139.427 168.098 147.481 1.00 95.11  ? 918  ALA A C   1 
ATOM   5342 O O   . ALA A 1 796  ? 139.489 167.062 148.152 1.00 104.99 ? 918  ALA A O   1 
ATOM   5343 C CB  . ALA A 1 796  ? 137.045 168.128 146.689 1.00 93.04  ? 918  ALA A CB  1 
ATOM   5344 N N   . ALA A 1 797  ? 140.137 169.191 147.757 1.00 87.04  ? 919  ALA A N   1 
ATOM   5345 C CA  . ALA A 1 797  ? 141.060 169.220 148.879 1.00 88.03  ? 919  ALA A CA  1 
ATOM   5346 C C   . ALA A 1 797  ? 141.144 170.633 149.434 1.00 87.13  ? 919  ALA A C   1 
ATOM   5347 O O   . ALA A 1 797  ? 140.915 171.616 148.725 1.00 87.17  ? 919  ALA A O   1 
ATOM   5348 C CB  . ALA A 1 797  ? 142.444 168.720 148.473 1.00 81.74  ? 919  ALA A CB  1 
ATOM   5349 N N   . ARG A 1 798  ? 141.495 170.719 150.713 1.00 84.84  ? 920  ARG A N   1 
ATOM   5350 C CA  . ARG A 1 798  ? 141.441 171.957 151.475 1.00 78.52  ? 920  ARG A CA  1 
ATOM   5351 C C   . ARG A 1 798  ? 142.819 172.282 152.032 1.00 79.64  ? 920  ARG A C   1 
ATOM   5352 O O   . ARG A 1 798  ? 143.521 171.396 152.527 1.00 79.23  ? 920  ARG A O   1 
ATOM   5353 C CB  . ARG A 1 798  ? 140.410 171.838 152.611 1.00 88.20  ? 920  ARG A CB  1 
ATOM   5354 C CG  . ARG A 1 798  ? 140.152 173.112 153.403 1.00 89.74  ? 920  ARG A CG  1 
ATOM   5355 C CD  . ARG A 1 798  ? 139.171 172.882 154.532 1.00 86.11  ? 920  ARG A CD  1 
ATOM   5356 N NE  . ARG A 1 798  ? 137.801 173.121 154.100 1.00 91.52  ? 920  ARG A NE  1 
ATOM   5357 C CZ  . ARG A 1 798  ? 137.150 174.259 154.290 1.00 93.96  ? 920  ARG A CZ  1 
ATOM   5358 N NH1 . ARG A 1 798  ? 137.712 175.279 154.917 1.00 88.91  ? 920  ARG A NH1 1 
ATOM   5359 N NH2 . ARG A 1 798  ? 135.905 174.376 153.839 1.00 92.87  ? 920  ARG A NH2 1 
ATOM   5360 N N   . THR A 1 799  ? 143.204 173.555 151.937 1.00 78.62  ? 921  THR A N   1 
ATOM   5361 C CA  . THR A 1 799  ? 144.452 174.036 152.503 1.00 75.38  ? 921  THR A CA  1 
ATOM   5362 C C   . THR A 1 799  ? 144.391 174.073 154.030 1.00 79.24  ? 921  THR A C   1 
ATOM   5363 O O   . THR A 1 799  ? 143.322 174.056 154.645 1.00 80.28  ? 921  THR A O   1 
ATOM   5364 C CB  . THR A 1 799  ? 144.776 175.439 151.983 1.00 73.26  ? 921  THR A CB  1 
ATOM   5365 O OG1 . THR A 1 799  ? 143.703 176.326 152.309 1.00 86.70  ? 921  THR A OG1 1 
ATOM   5366 C CG2 . THR A 1 799  ? 144.970 175.439 150.490 1.00 71.86  ? 921  THR A CG2 1 
ATOM   5367 N N   . TRP A 1 800  ? 145.573 174.133 154.639 1.00 78.08  ? 922  TRP A N   1 
ATOM   5368 C CA  . TRP A 1 800  ? 145.708 174.309 156.074 1.00 73.94  ? 922  TRP A CA  1 
ATOM   5369 C C   . TRP A 1 800  ? 145.339 175.736 156.477 1.00 80.31  ? 922  TRP A C   1 
ATOM   5370 O O   . TRP A 1 800  ? 145.365 176.648 155.648 1.00 86.52  ? 922  TRP A O   1 
ATOM   5371 C CB  . TRP A 1 800  ? 147.146 174.018 156.502 1.00 77.16  ? 922  TRP A CB  1 
ATOM   5372 C CG  . TRP A 1 800  ? 147.496 172.583 156.625 1.00 76.05  ? 922  TRP A CG  1 
ATOM   5373 C CD1 . TRP A 1 800  ? 147.546 171.662 155.626 1.00 71.38  ? 922  TRP A CD1 1 
ATOM   5374 C CD2 . TRP A 1 800  ? 147.882 171.903 157.821 1.00 78.87  ? 922  TRP A CD2 1 
ATOM   5375 N NE1 . TRP A 1 800  ? 147.929 170.445 156.124 1.00 71.04  ? 922  TRP A NE1 1 
ATOM   5376 C CE2 . TRP A 1 800  ? 148.146 170.565 157.471 1.00 76.53  ? 922  TRP A CE2 1 
ATOM   5377 C CE3 . TRP A 1 800  ? 148.029 172.295 159.157 1.00 79.62  ? 922  TRP A CE3 1 
ATOM   5378 C CZ2 . TRP A 1 800  ? 148.541 169.611 158.411 1.00 76.14  ? 922  TRP A CZ2 1 
ATOM   5379 C CZ3 . TRP A 1 800  ? 148.424 171.348 160.091 1.00 82.36  ? 922  TRP A CZ3 1 
ATOM   5380 C CH2 . TRP A 1 800  ? 148.675 170.021 159.711 1.00 78.53  ? 922  TRP A CH2 1 
ATOM   5381 N N   . PRO A 1 801  ? 144.981 175.957 157.743 1.00 78.85  ? 923  PRO A N   1 
ATOM   5382 C CA  . PRO A 1 801  ? 144.900 177.330 158.249 1.00 75.91  ? 923  PRO A CA  1 
ATOM   5383 C C   . PRO A 1 801  ? 146.273 177.964 158.409 1.00 80.48  ? 923  PRO A C   1 
ATOM   5384 O O   . PRO A 1 801  ? 147.308 177.295 158.431 1.00 91.96  ? 923  PRO A O   1 
ATOM   5385 C CB  . PRO A 1 801  ? 144.208 177.168 159.603 1.00 77.70  ? 923  PRO A CB  1 
ATOM   5386 C CG  . PRO A 1 801  ? 143.411 175.952 159.444 1.00 81.63  ? 923  PRO A CG  1 
ATOM   5387 C CD  . PRO A 1 801  ? 144.268 175.032 158.641 1.00 83.32  ? 923  PRO A CD  1 
ATOM   5388 N N   . LEU A 1 802  ? 146.255 179.288 158.527 1.00 79.59  ? 924  LEU A N   1 
ATOM   5389 C CA  . LEU A 1 802  ? 147.463 180.097 158.544 1.00 86.30  ? 924  LEU A CA  1 
ATOM   5390 C C   . LEU A 1 802  ? 148.190 179.961 159.883 1.00 91.51  ? 924  LEU A C   1 
ATOM   5391 O O   . LEU A 1 802  ? 147.575 179.758 160.934 1.00 93.00  ? 924  LEU A O   1 
ATOM   5392 C CB  . LEU A 1 802  ? 147.093 181.556 158.251 1.00 86.95  ? 924  LEU A CB  1 
ATOM   5393 C CG  . LEU A 1 802  ? 148.113 182.688 158.124 1.00 91.08  ? 924  LEU A CG  1 
ATOM   5394 C CD1 . LEU A 1 802  ? 149.046 182.432 156.961 1.00 85.49  ? 924  LEU A CD1 1 
ATOM   5395 C CD2 . LEU A 1 802  ? 147.400 184.019 157.961 1.00 94.42  ? 924  LEU A CD2 1 
ATOM   5396 N N   . GLY A 1 803  ? 149.518 180.061 159.828 1.00 91.50  ? 925  GLY A N   1 
ATOM   5397 C CA  . GLY A 1 803  ? 150.363 179.874 160.981 1.00 88.13  ? 925  GLY A CA  1 
ATOM   5398 C C   . GLY A 1 803  ? 151.528 178.957 160.661 1.00 94.51  ? 925  GLY A C   1 
ATOM   5399 O O   . GLY A 1 803  ? 151.497 178.218 159.677 1.00 102.99 ? 925  GLY A O   1 
ATOM   5400 N N   . PRO A 1 804  ? 152.604 179.022 161.447 1.00 87.65  ? 926  PRO A N   1 
ATOM   5401 C CA  . PRO A 1 804  ? 153.705 178.066 161.260 1.00 87.58  ? 926  PRO A CA  1 
ATOM   5402 C C   . PRO A 1 804  ? 153.382 176.747 161.945 1.00 82.11  ? 926  PRO A C   1 
ATOM   5403 O O   . PRO A 1 804  ? 153.420 176.651 163.173 1.00 86.75  ? 926  PRO A O   1 
ATOM   5404 C CB  . PRO A 1 804  ? 154.898 178.765 161.922 1.00 90.15  ? 926  PRO A CB  1 
ATOM   5405 C CG  . PRO A 1 804  ? 154.488 180.195 162.069 1.00 92.79  ? 926  PRO A CG  1 
ATOM   5406 C CD  . PRO A 1 804  ? 153.015 180.137 162.313 1.00 88.31  ? 926  PRO A CD  1 
ATOM   5407 N N   . HIS A 1 805  ? 153.086 175.724 161.149 1.00 73.98  ? 927  HIS A N   1 
ATOM   5408 C CA  . HIS A 1 805  ? 152.627 174.434 161.658 1.00 73.14  ? 927  HIS A CA  1 
ATOM   5409 C C   . HIS A 1 805  ? 153.789 173.468 161.489 1.00 73.83  ? 927  HIS A C   1 
ATOM   5410 O O   . HIS A 1 805  ? 154.002 172.939 160.398 1.00 79.94  ? 927  HIS A O   1 
ATOM   5411 C CB  . HIS A 1 805  ? 151.405 173.951 160.903 1.00 73.40  ? 927  HIS A CB  1 
ATOM   5412 C CG  . HIS A 1 805  ? 150.213 174.838 161.062 1.00 80.32  ? 927  HIS A CG  1 
ATOM   5413 N ND1 . HIS A 1 805  ? 149.455 174.880 162.212 1.00 92.76  ? 927  HIS A ND1 1 
ATOM   5414 C CD2 . HIS A 1 805  ? 149.646 175.717 160.205 1.00 79.50  ? 927  HIS A CD2 1 
ATOM   5415 C CE1 . HIS A 1 805  ? 148.485 175.763 162.059 1.00 91.80  ? 927  HIS A CE1 1 
ATOM   5416 N NE2 . HIS A 1 805  ? 148.581 176.287 160.851 1.00 85.96  ? 927  HIS A NE2 1 
ATOM   5417 N N   . ARG A 1 806  ? 154.526 173.213 162.564 1.00 70.26  ? 928  ARG A N   1 
ATOM   5418 C CA  . ARG A 1 806  ? 155.790 172.500 162.461 1.00 60.37  ? 928  ARG A CA  1 
ATOM   5419 C C   . ARG A 1 806  ? 155.566 171.024 162.765 1.00 60.29  ? 928  ARG A C   1 
ATOM   5420 O O   . ARG A 1 806  ? 155.126 170.677 163.862 1.00 68.61  ? 928  ARG A O   1 
ATOM   5421 C CB  . ARG A 1 806  ? 156.810 173.081 163.441 1.00 59.05  ? 928  ARG A CB  1 
ATOM   5422 C CG  . ARG A 1 806  ? 157.136 174.547 163.198 1.00 70.17  ? 928  ARG A CG  1 
ATOM   5423 C CD  . ARG A 1 806  ? 157.851 174.837 161.893 1.00 80.54  ? 928  ARG A CD  1 
ATOM   5424 N NE  . ARG A 1 806  ? 159.179 174.248 161.803 1.00 86.49  ? 928  ARG A NE  1 
ATOM   5425 C CZ  . ARG A 1 806  ? 159.844 174.099 160.667 1.00 83.40  ? 928  ARG A CZ  1 
ATOM   5426 N NH1 . ARG A 1 806  ? 159.310 174.433 159.505 1.00 78.39  ? 928  ARG A NH1 1 
ATOM   5427 N NH2 . ARG A 1 806  ? 161.081 173.611 160.699 1.00 85.42  ? 928  ARG A NH2 1 
ATOM   5428 N N   . LEU A 1 807  ? 155.874 170.161 161.803 1.00 60.43  ? 929  LEU A N   1 
ATOM   5429 C CA  . LEU A 1 807  ? 155.824 168.720 162.019 1.00 57.05  ? 929  LEU A CA  1 
ATOM   5430 C C   . LEU A 1 807  ? 157.168 168.249 162.543 1.00 59.38  ? 929  LEU A C   1 
ATOM   5431 O O   . LEU A 1 807  ? 158.211 168.571 161.968 1.00 72.59  ? 929  LEU A O   1 
ATOM   5432 C CB  . LEU A 1 807  ? 155.477 167.962 160.739 1.00 58.96  ? 929  LEU A CB  1 
ATOM   5433 C CG  . LEU A 1 807  ? 154.036 167.983 160.245 1.00 64.20  ? 929  LEU A CG  1 
ATOM   5434 C CD1 . LEU A 1 807  ? 153.935 167.201 158.956 1.00 69.43  ? 929  LEU A CD1 1 
ATOM   5435 C CD2 . LEU A 1 807  ? 153.110 167.402 161.290 1.00 66.46  ? 929  LEU A CD2 1 
ATOM   5436 N N   . ARG A 1 808  ? 157.143 167.479 163.623 1.00 57.33  ? 930  ARG A N   1 
ATOM   5437 C CA  . ARG A 1 808  ? 158.355 166.973 164.248 1.00 57.23  ? 930  ARG A CA  1 
ATOM   5438 C C   . ARG A 1 808  ? 158.533 165.509 163.877 1.00 61.95  ? 930  ARG A C   1 
ATOM   5439 O O   . ARG A 1 808  ? 157.643 164.690 164.125 1.00 68.95  ? 930  ARG A O   1 
ATOM   5440 C CB  . ARG A 1 808  ? 158.294 167.134 165.763 1.00 67.04  ? 930  ARG A CB  1 
ATOM   5441 C CG  . ARG A 1 808  ? 159.403 166.426 166.481 1.00 63.77  ? 930  ARG A CG  1 
ATOM   5442 C CD  . ARG A 1 808  ? 159.107 166.239 167.940 1.00 68.21  ? 930  ARG A CD  1 
ATOM   5443 N NE  . ARG A 1 808  ? 160.355 166.052 168.657 1.00 78.32  ? 930  ARG A NE  1 
ATOM   5444 C CZ  . ARG A 1 808  ? 160.912 164.873 168.883 1.00 81.18  ? 930  ARG A CZ  1 
ATOM   5445 N NH1 . ARG A 1 808  ? 160.310 163.747 168.537 1.00 71.26  ? 930  ARG A NH1 1 
ATOM   5446 N NH2 . ARG A 1 808  ? 162.109 164.823 169.450 1.00 79.57  ? 930  ARG A NH2 1 
ATOM   5447 N N   . TRP A 1 809  ? 159.678 165.185 163.292 1.00 62.83  ? 931  TRP A N   1 
ATOM   5448 C CA  . TRP A 1 809  ? 160.004 163.829 162.890 1.00 62.42  ? 931  TRP A CA  1 
ATOM   5449 C C   . TRP A 1 809  ? 161.078 163.260 163.799 1.00 74.08  ? 931  TRP A C   1 
ATOM   5450 O O   . TRP A 1 809  ? 161.805 163.997 164.466 1.00 81.35  ? 931  TRP A O   1 
ATOM   5451 C CB  . TRP A 1 809  ? 160.504 163.773 161.448 1.00 66.93  ? 931  TRP A CB  1 
ATOM   5452 C CG  . TRP A 1 809  ? 159.560 164.295 160.433 1.00 63.83  ? 931  TRP A CG  1 
ATOM   5453 C CD1 . TRP A 1 809  ? 159.354 165.598 160.090 1.00 61.22  ? 931  TRP A CD1 1 
ATOM   5454 C CD2 . TRP A 1 809  ? 158.700 163.520 159.601 1.00 65.77  ? 931  TRP A CD2 1 
ATOM   5455 N NE1 . TRP A 1 809  ? 158.410 165.683 159.106 1.00 59.62  ? 931  TRP A NE1 1 
ATOM   5456 C CE2 . TRP A 1 809  ? 157.995 164.419 158.782 1.00 62.83  ? 931  TRP A CE2 1 
ATOM   5457 C CE3 . TRP A 1 809  ? 158.455 162.148 159.469 1.00 73.09  ? 931  TRP A CE3 1 
ATOM   5458 C CZ2 . TRP A 1 809  ? 157.061 163.996 157.852 1.00 63.25  ? 931  TRP A CZ2 1 
ATOM   5459 C CZ3 . TRP A 1 809  ? 157.521 161.727 158.539 1.00 70.94  ? 931  TRP A CZ3 1 
ATOM   5460 C CH2 . TRP A 1 809  ? 156.840 162.649 157.739 1.00 66.04  ? 931  TRP A CH2 1 
ATOM   5461 N N   . ALA A 1 810  ? 161.174 161.938 163.814 1.00 69.34  ? 932  ALA A N   1 
ATOM   5462 C CA  . ALA A 1 810  ? 162.274 161.249 164.466 1.00 74.71  ? 932  ALA A CA  1 
ATOM   5463 C C   . ALA A 1 810  ? 162.649 160.053 163.614 1.00 85.15  ? 932  ALA A C   1 
ATOM   5464 O O   . ALA A 1 810  ? 161.813 159.182 163.361 1.00 88.20  ? 932  ALA A O   1 
ATOM   5465 C CB  . ALA A 1 810  ? 161.908 160.807 165.883 1.00 78.27  ? 932  ALA A CB  1 
ATOM   5466 N N   . SER A 1 811  ? 163.897 160.021 163.160 1.00 82.57  ? 933  SER A N   1 
ATOM   5467 C CA  . SER A 1 811  ? 164.365 158.899 162.370 1.00 83.48  ? 933  SER A CA  1 
ATOM   5468 C C   . SER A 1 811  ? 164.650 157.705 163.268 1.00 85.67  ? 933  SER A C   1 
ATOM   5469 O O   . SER A 1 811  ? 164.799 157.836 164.482 1.00 91.55  ? 933  SER A O   1 
ATOM   5470 C CB  . SER A 1 811  ? 165.622 159.269 161.593 1.00 87.77  ? 933  SER A CB  1 
ATOM   5471 O OG  . SER A 1 811  ? 166.640 159.711 162.466 1.00 88.95  ? 933  SER A OG  1 
ATOM   5472 N N   . ARG A 1 812  ? 164.759 156.528 162.644 1.00 82.82  ? 934  ARG A N   1 
ATOM   5473 C CA  . ARG A 1 812  ? 165.068 155.302 163.374 1.00 80.59  ? 934  ARG A CA  1 
ATOM   5474 C C   . ARG A 1 812  ? 166.516 155.244 163.843 1.00 87.72  ? 934  ARG A C   1 
ATOM   5475 O O   . ARG A 1 812  ? 166.823 154.485 164.766 1.00 91.64  ? 934  ARG A O   1 
ATOM   5476 C CB  . ARG A 1 812  ? 164.765 154.086 162.503 1.00 78.61  ? 934  ARG A CB  1 
ATOM   5477 C CG  . ARG A 1 812  ? 163.298 153.882 162.215 1.00 78.95  ? 934  ARG A CG  1 
ATOM   5478 C CD  . ARG A 1 812  ? 163.076 152.606 161.438 1.00 76.74  ? 934  ARG A CD  1 
ATOM   5479 N NE  . ARG A 1 812  ? 161.686 152.450 161.032 1.00 86.07  ? 934  ARG A NE  1 
ATOM   5480 C CZ  . ARG A 1 812  ? 161.244 151.484 160.240 1.00 94.58  ? 934  ARG A CZ  1 
ATOM   5481 N NH1 . ARG A 1 812  ? 162.062 150.571 159.743 1.00 91.94  ? 934  ARG A NH1 1 
ATOM   5482 N NH2 . ARG A 1 812  ? 159.951 151.432 159.939 1.00 96.76  ? 934  ARG A NH2 1 
ATOM   5483 N N   . GLN A 1 813  ? 167.410 156.019 163.224 1.00 90.58  ? 935  GLN A N   1 
ATOM   5484 C CA  . GLN A 1 813  ? 168.766 156.151 163.740 1.00 93.49  ? 935  GLN A CA  1 
ATOM   5485 C C   . GLN A 1 813  ? 168.772 157.020 164.994 1.00 94.54  ? 935  GLN A C   1 
ATOM   5486 O O   . GLN A 1 813  ? 169.613 156.838 165.882 1.00 96.07  ? 935  GLN A O   1 
ATOM   5487 C CB  . GLN A 1 813  ? 169.674 156.712 162.634 1.00 85.97  ? 935  GLN A CB  1 
ATOM   5488 C CG  . GLN A 1 813  ? 171.196 156.749 162.885 1.00 94.09  ? 935  GLN A CG  1 
ATOM   5489 C CD  . GLN A 1 813  ? 171.696 157.984 163.611 1.00 101.51 ? 935  GLN A CD  1 
ATOM   5490 O OE1 . GLN A 1 813  ? 171.115 159.061 163.500 1.00 103.75 ? 935  GLN A OE1 1 
ATOM   5491 N NE2 . GLN A 1 813  ? 172.787 157.831 164.353 1.00 99.92  ? 935  GLN A NE2 1 
ATOM   5492 N N   . GLY A 1 814  ? 167.842 157.969 165.085 1.00 89.23  ? 936  GLY A N   1 
ATOM   5493 C CA  . GLY A 1 814  ? 167.688 158.760 166.289 1.00 83.91  ? 936  GLY A CA  1 
ATOM   5494 C C   . GLY A 1 814  ? 167.817 160.254 166.084 1.00 87.03  ? 936  GLY A C   1 
ATOM   5495 O O   . GLY A 1 814  ? 168.017 160.997 167.048 1.00 89.91  ? 936  GLY A O   1 
ATOM   5496 N N   . SER A 1 815  ? 167.708 160.710 164.842 1.00 91.02  ? 937  SER A N   1 
ATOM   5497 C CA  . SER A 1 815  ? 167.845 162.125 164.533 1.00 87.85  ? 937  SER A CA  1 
ATOM   5498 C C   . SER A 1 815  ? 166.475 162.771 164.363 1.00 85.34  ? 937  SER A C   1 
ATOM   5499 O O   . SER A 1 815  ? 165.529 162.150 163.872 1.00 86.09  ? 937  SER A O   1 
ATOM   5500 C CB  . SER A 1 815  ? 168.682 162.322 163.269 1.00 90.79  ? 937  SER A CB  1 
ATOM   5501 O OG  . SER A 1 815  ? 168.308 161.402 162.261 1.00 90.46  ? 937  SER A OG  1 
ATOM   5502 N N   . VAL A 1 816  ? 166.382 164.032 164.775 1.00 80.63  ? 938  VAL A N   1 
ATOM   5503 C CA  . VAL A 1 816  ? 165.122 164.763 164.855 1.00 75.95  ? 938  VAL A CA  1 
ATOM   5504 C C   . VAL A 1 816  ? 165.204 165.956 163.914 1.00 82.80  ? 938  VAL A C   1 
ATOM   5505 O O   . VAL A 1 816  ? 166.099 166.798 164.053 1.00 87.01  ? 938  VAL A O   1 
ATOM   5506 C CB  . VAL A 1 816  ? 164.832 165.223 166.294 1.00 79.15  ? 938  VAL A CB  1 
ATOM   5507 C CG1 . VAL A 1 816  ? 163.626 166.147 166.351 1.00 76.54  ? 938  VAL A CG1 1 
ATOM   5508 C CG2 . VAL A 1 816  ? 164.636 164.027 167.207 1.00 82.42  ? 938  VAL A CG2 1 
ATOM   5509 N N   . ILE A 1 817  ? 164.277 166.031 162.957 1.00 80.98  ? 939  ILE A N   1 
ATOM   5510 C CA  . ILE A 1 817  ? 164.150 167.187 162.080 1.00 77.01  ? 939  ILE A CA  1 
ATOM   5511 C C   . ILE A 1 817  ? 162.767 167.797 162.270 1.00 72.23  ? 939  ILE A C   1 
ATOM   5512 O O   . ILE A 1 817  ? 161.830 167.132 162.722 1.00 74.54  ? 939  ILE A O   1 
ATOM   5513 C CB  . ILE A 1 817  ? 164.390 166.838 160.592 1.00 75.75  ? 939  ILE A CB  1 
ATOM   5514 C CG1 . ILE A 1 817  ? 163.435 165.745 160.127 1.00 73.89  ? 939  ILE A CG1 1 
ATOM   5515 C CG2 . ILE A 1 817  ? 165.817 166.394 160.370 1.00 80.79  ? 939  ILE A CG2 1 
ATOM   5516 C CD1 . ILE A 1 817  ? 163.358 165.606 158.638 1.00 79.52  ? 939  ILE A CD1 1 
ATOM   5517 N N   . HIS A 1 818  ? 162.652 169.080 161.937 1.00 70.27  ? 940  HIS A N   1 
ATOM   5518 C CA  . HIS A 1 818  ? 161.391 169.813 162.012 1.00 64.26  ? 940  HIS A CA  1 
ATOM   5519 C C   . HIS A 1 818  ? 161.052 170.328 160.623 1.00 73.38  ? 940  HIS A C   1 
ATOM   5520 O O   . HIS A 1 818  ? 161.730 171.219 160.105 1.00 86.53  ? 940  HIS A O   1 
ATOM   5521 C CB  . HIS A 1 818  ? 161.474 170.974 162.998 1.00 65.65  ? 940  HIS A CB  1 
ATOM   5522 C CG  . HIS A 1 818  ? 161.378 170.563 164.432 1.00 73.18  ? 940  HIS A CG  1 
ATOM   5523 N ND1 . HIS A 1 818  ? 161.293 171.475 165.460 1.00 74.96  ? 940  HIS A ND1 1 
ATOM   5524 C CD2 . HIS A 1 818  ? 161.365 169.340 165.010 1.00 78.54  ? 940  HIS A CD2 1 
ATOM   5525 C CE1 . HIS A 1 818  ? 161.232 170.832 166.611 1.00 76.76  ? 940  HIS A CE1 1 
ATOM   5526 N NE2 . HIS A 1 818  ? 161.270 169.535 166.366 1.00 82.24  ? 940  HIS A NE2 1 
ATOM   5527 N N   . THR A 1 819  ? 160.008 169.777 160.024 1.00 67.23  ? 941  THR A N   1 
ATOM   5528 C CA  . THR A 1 819  ? 159.520 170.219 158.733 1.00 63.58  ? 941  THR A CA  1 
ATOM   5529 C C   . THR A 1 819  ? 158.281 171.085 158.924 1.00 70.49  ? 941  THR A C   1 
ATOM   5530 O O   . THR A 1 819  ? 157.972 171.531 160.029 1.00 80.07  ? 941  THR A O   1 
ATOM   5531 C CB  . THR A 1 819  ? 159.242 169.018 157.837 1.00 69.25  ? 941  THR A CB  1 
ATOM   5532 O OG1 . THR A 1 819  ? 158.160 168.256 158.381 1.00 71.05  ? 941  THR A OG1 1 
ATOM   5533 C CG2 . THR A 1 819  ? 160.464 168.146 157.761 1.00 77.61  ? 941  THR A CG2 1 
ATOM   5534 N N   . ASN A 1 820  ? 157.571 171.346 157.832 1.00 69.35  ? 942  ASN A N   1 
ATOM   5535 C CA  . ASN A 1 820  ? 156.307 172.062 157.814 1.00 66.24  ? 942  ASN A CA  1 
ATOM   5536 C C   . ASN A 1 820  ? 155.187 171.130 157.331 1.00 73.76  ? 942  ASN A C   1 
ATOM   5537 O O   . ASN A 1 820  ? 155.312 169.902 157.451 1.00 74.88  ? 942  ASN A O   1 
ATOM   5538 C CB  . ASN A 1 820  ? 156.469 173.425 157.078 1.00 66.89  ? 942  ASN A CB  1 
ATOM   5539 C CG  . ASN A 1 820  ? 156.674 173.364 155.526 1.00 81.68  ? 942  ASN A CG  1 
ATOM   5540 O OD1 . ASN A 1 820  ? 156.458 172.383 154.816 1.00 81.11  ? 942  ASN A OD1 1 
ATOM   5541 N ND2 . ASN A 1 820  ? 157.105 174.505 155.010 1.00 82.70  ? 942  ASN A ND2 1 
ATOM   5542 N N   . GLU A 1 821  ? 154.067 171.731 156.893 1.00 75.82  ? 943  GLU A N   1 
ATOM   5543 C CA  . GLU A 1 821  ? 152.874 171.011 156.436 1.00 71.87  ? 943  GLU A CA  1 
ATOM   5544 C C   . GLU A 1 821  ? 153.154 170.124 155.227 1.00 81.83  ? 943  GLU A C   1 
ATOM   5545 O O   . GLU A 1 821  ? 152.610 169.021 155.128 1.00 83.33  ? 943  GLU A O   1 
ATOM   5546 C CB  . GLU A 1 821  ? 151.776 171.985 156.009 1.00 70.77  ? 943  GLU A CB  1 
ATOM   5547 C CG  . GLU A 1 821  ? 151.227 172.975 157.004 1.00 75.50  ? 943  GLU A CG  1 
ATOM   5548 C CD  . GLU A 1 821  ? 152.027 174.266 157.030 1.00 83.87  ? 943  GLU A CD  1 
ATOM   5549 O OE1 . GLU A 1 821  ? 152.971 174.400 156.230 1.00 77.90  ? 943  GLU A OE1 1 
ATOM   5550 O OE2 . GLU A 1 821  ? 151.684 175.175 157.806 1.00 96.14  ? 943  GLU A OE2 1 
ATOM   5551 N N   . LEU A 1 822  ? 153.979 170.599 154.298 1.00 79.65  ? 944  LEU A N   1 
ATOM   5552 C CA  . LEU A 1 822  ? 154.304 169.879 153.078 1.00 77.18  ? 944  LEU A CA  1 
ATOM   5553 C C   . LEU A 1 822  ? 155.543 169.006 153.210 1.00 84.99  ? 944  LEU A C   1 
ATOM   5554 O O   . LEU A 1 822  ? 155.829 168.223 152.298 1.00 95.40  ? 944  LEU A O   1 
ATOM   5555 C CB  . LEU A 1 822  ? 154.503 170.869 151.931 1.00 79.50  ? 944  LEU A CB  1 
ATOM   5556 C CG  . LEU A 1 822  ? 153.259 171.586 151.426 1.00 77.60  ? 944  LEU A CG  1 
ATOM   5557 C CD1 . LEU A 1 822  ? 153.645 172.869 150.730 1.00 79.82  ? 944  LEU A CD1 1 
ATOM   5558 C CD2 . LEU A 1 822  ? 152.504 170.680 150.485 1.00 78.21  ? 944  LEU A CD2 1 
ATOM   5559 N N   . GLY A 1 823  ? 156.282 169.117 154.307 1.00 76.35  ? 945  GLY A N   1 
ATOM   5560 C CA  . GLY A 1 823  ? 157.498 168.346 154.455 1.00 75.47  ? 945  GLY A CA  1 
ATOM   5561 C C   . GLY A 1 823  ? 158.756 169.042 153.999 1.00 79.64  ? 945  GLY A C   1 
ATOM   5562 O O   . GLY A 1 823  ? 159.795 168.391 153.873 1.00 84.05  ? 945  GLY A O   1 
ATOM   5563 N N   . GLU A 1 824  ? 158.696 170.341 153.734 1.00 77.59  ? 946  GLU A N   1 
ATOM   5564 C CA  . GLU A 1 824  ? 159.852 171.138 153.354 1.00 83.62  ? 946  GLU A CA  1 
ATOM   5565 C C   . GLU A 1 824  ? 160.221 172.068 154.506 1.00 81.34  ? 946  GLU A C   1 
ATOM   5566 O O   . GLU A 1 824  ? 159.583 172.059 155.560 1.00 86.09  ? 946  GLU A O   1 
ATOM   5567 C CB  . GLU A 1 824  ? 159.566 171.914 152.067 1.00 91.08  ? 946  GLU A CB  1 
ATOM   5568 C CG  . GLU A 1 824  ? 158.479 172.964 152.208 1.00 96.16  ? 946  GLU A CG  1 
ATOM   5569 C CD  . GLU A 1 824  ? 158.160 173.678 150.912 1.00 101.25 ? 946  GLU A CD  1 
ATOM   5570 O OE1 . GLU A 1 824  ? 158.773 173.343 149.877 1.00 109.94 ? 946  GLU A OE1 1 
ATOM   5571 O OE2 . GLU A 1 824  ? 157.292 174.575 150.931 1.00 100.63 ? 946  GLU A OE2 1 
ATOM   5572 N N   . GLY A 1 825  ? 161.255 172.882 154.287 1.00 83.28  ? 947  GLY A N   1 
ATOM   5573 C CA  . GLY A 1 825  ? 161.735 173.818 155.291 1.00 76.95  ? 947  GLY A CA  1 
ATOM   5574 C C   . GLY A 1 825  ? 162.397 173.149 156.477 1.00 79.10  ? 947  GLY A C   1 
ATOM   5575 O O   . GLY A 1 825  ? 162.065 173.450 157.628 1.00 74.05  ? 947  GLY A O   1 
ATOM   5576 N N   . LEU A 1 826  ? 163.324 172.235 156.199 1.00 85.27  ? 948  LEU A N   1 
ATOM   5577 C CA  . LEU A 1 826  ? 163.834 171.300 157.195 1.00 78.10  ? 948  LEU A CA  1 
ATOM   5578 C C   . LEU A 1 826  ? 164.838 171.982 158.113 1.00 82.32  ? 948  LEU A C   1 
ATOM   5579 O O   . LEU A 1 826  ? 165.677 172.767 157.658 1.00 85.43  ? 948  LEU A O   1 
ATOM   5580 C CB  . LEU A 1 826  ? 164.490 170.088 156.537 1.00 76.33  ? 948  LEU A CB  1 
ATOM   5581 C CG  . LEU A 1 826  ? 163.708 168.920 155.923 1.00 91.94  ? 948  LEU A CG  1 
ATOM   5582 C CD1 . LEU A 1 826  ? 162.988 169.223 154.612 1.00 88.33  ? 948  LEU A CD1 1 
ATOM   5583 C CD2 . LEU A 1 826  ? 164.622 167.742 155.753 1.00 92.23  ? 948  LEU A CD2 1 
ATOM   5584 N N   . GLU A 1 827  ? 164.748 171.677 159.400 1.00 77.64  ? 949  GLU A N   1 
ATOM   5585 C CA  . GLU A 1 827  ? 165.676 172.163 160.411 1.00 81.81  ? 949  GLU A CA  1 
ATOM   5586 C C   . GLU A 1 827  ? 166.140 170.957 161.217 1.00 84.85  ? 949  GLU A C   1 
ATOM   5587 O O   . GLU A 1 827  ? 165.358 170.380 161.978 1.00 81.19  ? 949  GLU A O   1 
ATOM   5588 C CB  . GLU A 1 827  ? 165.005 173.206 161.300 1.00 84.81  ? 949  GLU A CB  1 
ATOM   5589 C CG  . GLU A 1 827  ? 165.853 173.692 162.458 1.00 98.77  ? 949  GLU A CG  1 
ATOM   5590 C CD  . GLU A 1 827  ? 165.178 174.800 163.241 1.00 111.77 ? 949  GLU A CD  1 
ATOM   5591 O OE1 . GLU A 1 827  ? 164.263 175.446 162.689 1.00 112.84 ? 949  GLU A OE1 1 
ATOM   5592 O OE2 . GLU A 1 827  ? 165.557 175.022 164.410 1.00 113.10 ? 949  GLU A OE2 1 
ATOM   5593 N N   . VAL A 1 828  ? 167.400 170.571 161.038 1.00 94.35  ? 950  VAL A N   1 
ATOM   5594 C CA  . VAL A 1 828  ? 167.962 169.422 161.740 1.00 92.51  ? 950  VAL A CA  1 
ATOM   5595 C C   . VAL A 1 828  ? 168.285 169.863 163.162 1.00 95.37  ? 950  VAL A C   1 
ATOM   5596 O O   . VAL A 1 828  ? 169.120 170.745 163.373 1.00 97.36  ? 950  VAL A O   1 
ATOM   5597 C CB  . VAL A 1 828  ? 169.208 168.878 161.033 1.00 91.92  ? 950  VAL A CB  1 
ATOM   5598 C CG1 . VAL A 1 828  ? 169.766 167.689 161.793 1.00 88.47  ? 950  VAL A CG1 1 
ATOM   5599 C CG2 . VAL A 1 828  ? 168.891 168.505 159.597 1.00 90.58  ? 950  VAL A CG2 1 
ATOM   5600 N N   . GLN A 1 829  ? 167.620 169.255 164.137 1.00 88.84  ? 951  GLN A N   1 
ATOM   5601 C CA  . GLN A 1 829  ? 167.770 169.671 165.520 1.00 87.78  ? 951  GLN A CA  1 
ATOM   5602 C C   . GLN A 1 829  ? 169.027 169.077 166.135 1.00 93.17  ? 951  GLN A C   1 
ATOM   5603 O O   . GLN A 1 829  ? 169.614 168.127 165.612 1.00 98.81  ? 951  GLN A O   1 
ATOM   5604 C CB  . GLN A 1 829  ? 166.537 169.282 166.328 1.00 86.42  ? 951  GLN A CB  1 
ATOM   5605 C CG  . GLN A 1 829  ? 165.259 169.770 165.695 1.00 79.78  ? 951  GLN A CG  1 
ATOM   5606 C CD  . GLN A 1 829  ? 164.973 171.205 166.059 1.00 85.00  ? 951  GLN A CD  1 
ATOM   5607 O OE1 . GLN A 1 829  ? 165.317 171.659 167.149 1.00 91.00  ? 951  GLN A OE1 1 
ATOM   5608 N NE2 . GLN A 1 829  ? 164.374 171.940 165.138 1.00 85.81  ? 951  GLN A NE2 1 
ATOM   5609 N N   . GLN A 1 830  ? 169.442 169.657 167.262 1.00 92.07  ? 952  GLN A N   1 
ATOM   5610 C CA  . GLN A 1 830  ? 170.747 169.334 167.827 1.00 94.29  ? 952  GLN A CA  1 
ATOM   5611 C C   . GLN A 1 830  ? 170.683 168.042 168.641 1.00 95.95  ? 952  GLN A C   1 
ATOM   5612 O O   . GLN A 1 830  ? 171.707 167.379 168.847 1.00 98.95  ? 952  GLN A O   1 
ATOM   5613 C CB  . GLN A 1 830  ? 171.229 170.541 168.655 1.00 93.34  ? 952  GLN A CB  1 
ATOM   5614 C CG  . GLN A 1 830  ? 172.674 170.550 169.203 1.00 98.75  ? 952  GLN A CG  1 
ATOM   5615 C CD  . GLN A 1 830  ? 172.832 169.846 170.538 1.00 111.62 ? 952  GLN A CD  1 
ATOM   5616 O OE1 . GLN A 1 830  ? 171.903 169.805 171.344 1.00 112.04 ? 952  GLN A OE1 1 
ATOM   5617 N NE2 . GLN A 1 830  ? 174.009 169.276 170.772 1.00 114.15 ? 952  GLN A NE2 1 
ATOM   5618 N N   . GLU A 1 831  ? 169.484 167.634 169.058 1.00 95.20  ? 953  GLU A N   1 
ATOM   5619 C CA  . GLU A 1 831  ? 169.352 166.473 169.931 1.00 92.44  ? 953  GLU A CA  1 
ATOM   5620 C C   . GLU A 1 831  ? 169.461 165.168 169.147 1.00 92.92  ? 953  GLU A C   1 
ATOM   5621 O O   . GLU A 1 831  ? 169.071 165.087 167.978 1.00 86.65  ? 953  GLU A O   1 
ATOM   5622 C CB  . GLU A 1 831  ? 168.033 166.533 170.709 1.00 90.87  ? 953  GLU A CB  1 
ATOM   5623 C CG  . GLU A 1 831  ? 166.762 166.585 169.871 1.00 90.84  ? 953  GLU A CG  1 
ATOM   5624 C CD  . GLU A 1 831  ? 166.211 167.986 169.728 1.00 95.24  ? 953  GLU A CD  1 
ATOM   5625 O OE1 . GLU A 1 831  ? 166.936 168.950 170.049 1.00 99.29  ? 953  GLU A OE1 1 
ATOM   5626 O OE2 . GLU A 1 831  ? 165.051 168.124 169.289 1.00 94.05  ? 953  GLU A OE2 1 
ATOM   5627 N N   . GLN A 1 832  ? 170.043 164.158 169.789 1.00 91.97  ? 954  GLN A N   1 
ATOM   5628 C CA  . GLN A 1 832  ? 170.235 162.834 169.208 1.00 88.43  ? 954  GLN A CA  1 
ATOM   5629 C C   . GLN A 1 832  ? 169.588 161.817 170.135 1.00 89.45  ? 954  GLN A C   1 
ATOM   5630 O O   . GLN A 1 832  ? 170.053 161.611 171.260 1.00 88.95  ? 954  GLN A O   1 
ATOM   5631 C CB  . GLN A 1 832  ? 171.716 162.530 169.006 1.00 89.27  ? 954  GLN A CB  1 
ATOM   5632 C CG  . GLN A 1 832  ? 171.981 161.189 168.347 1.00 91.75  ? 954  GLN A CG  1 
ATOM   5633 C CD  . GLN A 1 832  ? 171.839 161.236 166.844 1.00 99.63  ? 954  GLN A CD  1 
ATOM   5634 O OE1 . GLN A 1 832  ? 171.902 162.301 166.234 1.00 107.23 ? 954  GLN A OE1 1 
ATOM   5635 N NE2 . GLN A 1 832  ? 171.644 160.075 166.235 1.00 97.13  ? 954  GLN A NE2 1 
ATOM   5636 N N   . LEU A 1 833  ? 168.521 161.186 169.662 1.00 90.78  ? 955  LEU A N   1 
ATOM   5637 C CA  . LEU A 1 833  ? 167.783 160.255 170.493 1.00 82.03  ? 955  LEU A CA  1 
ATOM   5638 C C   . LEU A 1 833  ? 168.333 158.844 170.327 1.00 90.52  ? 955  LEU A C   1 
ATOM   5639 O O   . LEU A 1 833  ? 169.296 158.603 169.596 1.00 101.44 ? 955  LEU A O   1 
ATOM   5640 C CB  . LEU A 1 833  ? 166.294 160.295 170.151 1.00 77.34  ? 955  LEU A CB  1 
ATOM   5641 C CG  . LEU A 1 833  ? 165.584 161.650 170.202 1.00 77.12  ? 955  LEU A CG  1 
ATOM   5642 C CD1 . LEU A 1 833  ? 164.096 161.455 170.014 1.00 78.50  ? 955  LEU A CD1 1 
ATOM   5643 C CD2 . LEU A 1 833  ? 165.867 162.391 171.502 1.00 78.29  ? 955  LEU A CD2 1 
ATOM   5644 N N   . GLU A 1 834  ? 167.709 157.902 171.023 1.00 83.50  ? 956  GLU A N   1 
ATOM   5645 C CA  . GLU A 1 834  ? 168.108 156.512 170.900 1.00 80.76  ? 956  GLU A CA  1 
ATOM   5646 C C   . GLU A 1 834  ? 167.457 155.883 169.673 1.00 84.08  ? 956  GLU A C   1 
ATOM   5647 O O   . GLU A 1 834  ? 166.645 156.501 168.980 1.00 89.23  ? 956  GLU A O   1 
ATOM   5648 C CB  . GLU A 1 834  ? 167.757 155.747 172.171 1.00 77.26  ? 956  GLU A CB  1 
ATOM   5649 C CG  . GLU A 1 834  ? 168.280 156.415 173.428 1.00 81.28  ? 956  GLU A CG  1 
ATOM   5650 C CD  . GLU A 1 834  ? 169.669 155.945 173.803 1.00 91.04  ? 956  GLU A CD  1 
ATOM   5651 O OE1 . GLU A 1 834  ? 170.097 154.891 173.290 1.00 92.36  ? 956  GLU A OE1 1 
ATOM   5652 O OE2 . GLU A 1 834  ? 170.334 156.629 174.607 1.00 91.37  ? 956  GLU A OE2 1 
ATOM   5653 N N   . ARG A 1 835  ? 167.838 154.637 169.398 1.00 87.68  ? 957  ARG A N   1 
ATOM   5654 C CA  . ARG A 1 835  ? 167.407 153.956 168.184 1.00 88.25  ? 957  ARG A CA  1 
ATOM   5655 C C   . ARG A 1 835  ? 165.956 153.497 168.289 1.00 84.24  ? 957  ARG A C   1 
ATOM   5656 O O   . ARG A 1 835  ? 165.534 152.908 169.284 1.00 85.23  ? 957  ARG A O   1 
ATOM   5657 C CB  . ARG A 1 835  ? 168.304 152.757 167.892 1.00 90.05  ? 957  ARG A CB  1 
ATOM   5658 C CG  . ARG A 1 835  ? 169.649 153.110 167.285 1.00 89.90  ? 957  ARG A CG  1 
ATOM   5659 C CD  . ARG A 1 835  ? 170.169 151.989 166.389 1.00 95.53  ? 957  ARG A CD  1 
ATOM   5660 N NE  . ARG A 1 835  ? 169.423 151.876 165.139 1.00 105.93 ? 957  ARG A NE  1 
ATOM   5661 C CZ  . ARG A 1 835  ? 168.568 150.901 164.853 1.00 107.74 ? 957  ARG A CZ  1 
ATOM   5662 N NH1 . ARG A 1 835  ? 168.316 149.930 165.715 1.00 102.68 ? 957  ARG A NH1 1 
ATOM   5663 N NH2 . ARG A 1 835  ? 167.946 150.906 163.678 1.00 98.59  ? 957  ARG A NH2 1 
ATOM   5664 N N   . LEU A 1 836  ? 165.214 153.745 167.204 1.00 81.41  ? 958  LEU A N   1 
ATOM   5665 C CA  . LEU A 1 836  ? 163.758 153.677 167.028 1.00 79.24  ? 958  LEU A CA  1 
ATOM   5666 C C   . LEU A 1 836  ? 162.966 154.377 168.136 1.00 82.52  ? 958  LEU A C   1 
ATOM   5667 O O   . LEU A 1 836  ? 162.334 153.688 168.947 1.00 91.27  ? 958  LEU A O   1 
ATOM   5668 C CB  . LEU A 1 836  ? 163.293 152.218 166.920 1.00 84.85  ? 958  LEU A CB  1 
ATOM   5669 C CG  . LEU A 1 836  ? 163.307 151.475 165.583 1.00 91.57  ? 958  LEU A CG  1 
ATOM   5670 C CD1 . LEU A 1 836  ? 164.693 150.952 165.233 1.00 92.99  ? 958  LEU A CD1 1 
ATOM   5671 C CD2 . LEU A 1 836  ? 162.300 150.338 165.614 1.00 90.05  ? 958  LEU A CD2 1 
ATOM   5672 N N   . PRO A 1 837  ? 162.947 155.716 168.215 1.00 78.24  ? 959  PRO A N   1 
ATOM   5673 C CA  . PRO A 1 837  ? 162.178 156.362 169.282 1.00 79.56  ? 959  PRO A CA  1 
ATOM   5674 C C   . PRO A 1 837  ? 160.710 156.512 168.915 1.00 78.39  ? 959  PRO A C   1 
ATOM   5675 O O   . PRO A 1 837  ? 160.327 156.433 167.748 1.00 86.26  ? 959  PRO A O   1 
ATOM   5676 C CB  . PRO A 1 837  ? 162.856 157.724 169.421 1.00 81.32  ? 959  PRO A CB  1 
ATOM   5677 C CG  . PRO A 1 837  ? 163.330 158.027 168.083 1.00 77.09  ? 959  PRO A CG  1 
ATOM   5678 C CD  . PRO A 1 837  ? 163.653 156.729 167.408 1.00 80.20  ? 959  PRO A CD  1 
ATOM   5679 N N   . GLY A 1 838  ? 159.884 156.722 169.934 1.00 76.02  ? 960  GLY A N   1 
ATOM   5680 C CA  . GLY A 1 838  ? 158.486 157.009 169.730 1.00 73.80  ? 960  GLY A CA  1 
ATOM   5681 C C   . GLY A 1 838  ? 158.225 158.499 169.780 1.00 78.29  ? 960  GLY A C   1 
ATOM   5682 O O   . GLY A 1 838  ? 159.154 159.304 169.660 1.00 82.67  ? 960  GLY A O   1 
ATOM   5683 N N   . PRO A 1 839  ? 156.957 158.899 169.917 1.00 76.98  ? 961  PRO A N   1 
ATOM   5684 C CA  . PRO A 1 839  ? 156.647 160.325 170.055 1.00 76.20  ? 961  PRO A CA  1 
ATOM   5685 C C   . PRO A 1 839  ? 157.041 160.851 171.426 1.00 73.84  ? 961  PRO A C   1 
ATOM   5686 O O   . PRO A 1 839  ? 156.869 160.183 172.446 1.00 76.25  ? 961  PRO A O   1 
ATOM   5687 C CB  . PRO A 1 839  ? 155.128 160.374 169.859 1.00 77.97  ? 961  PRO A CB  1 
ATOM   5688 C CG  . PRO A 1 839  ? 154.807 159.128 169.123 1.00 72.77  ? 961  PRO A CG  1 
ATOM   5689 C CD  . PRO A 1 839  ? 155.729 158.116 169.708 1.00 72.45  ? 961  PRO A CD  1 
ATOM   5690 N N   . MET A 1 840  ? 157.579 162.065 171.440 1.00 68.95  ? 962  MET A N   1 
ATOM   5691 C CA  . MET A 1 840  ? 158.107 162.659 172.657 1.00 68.01  ? 962  MET A CA  1 
ATOM   5692 C C   . MET A 1 840  ? 157.037 163.492 173.342 1.00 66.46  ? 962  MET A C   1 
ATOM   5693 O O   . MET A 1 840  ? 156.382 164.326 172.710 1.00 73.03  ? 962  MET A O   1 
ATOM   5694 C CB  . MET A 1 840  ? 159.335 163.517 172.359 1.00 67.64  ? 962  MET A CB  1 
ATOM   5695 C CG  . MET A 1 840  ? 160.018 164.072 173.591 1.00 64.09  ? 962  MET A CG  1 
ATOM   5696 S SD  . MET A 1 840  ? 161.456 165.050 173.184 1.00 101.39 ? 962  MET A SD  1 
ATOM   5697 C CE  . MET A 1 840  ? 162.538 163.752 172.678 1.00 84.78  ? 962  MET A CE  1 
ATOM   5698 N N   . THR A 1 841  ? 156.859 163.254 174.638 1.00 64.02  ? 963  THR A N   1 
ATOM   5699 C CA  . THR A 1 841  ? 155.868 163.951 175.447 1.00 63.17  ? 963  THR A CA  1 
ATOM   5700 C C   . THR A 1 841  ? 156.569 165.056 176.224 1.00 64.00  ? 963  THR A C   1 
ATOM   5701 O O   . THR A 1 841  ? 157.477 164.784 177.012 1.00 67.98  ? 963  THR A O   1 
ATOM   5702 C CB  . THR A 1 841  ? 155.167 162.984 176.395 1.00 64.21  ? 963  THR A CB  1 
ATOM   5703 O OG1 . THR A 1 841  ? 154.836 161.783 175.690 1.00 72.72  ? 963  THR A OG1 1 
ATOM   5704 C CG2 . THR A 1 841  ? 153.898 163.603 176.910 1.00 68.12  ? 963  THR A CG2 1 
ATOM   5705 N N   . MET A 1 842  ? 156.146 166.296 175.997 1.00 64.81  ? 964  MET A N   1 
ATOM   5706 C CA  . MET A 1 842  ? 156.627 167.427 176.776 1.00 64.93  ? 964  MET A CA  1 
ATOM   5707 C C   . MET A 1 842  ? 156.092 167.406 178.198 1.00 72.59  ? 964  MET A C   1 
ATOM   5708 O O   . MET A 1 842  ? 154.924 167.094 178.436 1.00 79.73  ? 964  MET A O   1 
ATOM   5709 C CB  . MET A 1 842  ? 156.216 168.749 176.127 1.00 78.41  ? 964  MET A CB  1 
ATOM   5710 C CG  . MET A 1 842  ? 156.801 169.121 174.771 1.00 92.37  ? 964  MET A CG  1 
ATOM   5711 S SD  . MET A 1 842  ? 158.594 169.325 174.727 1.00 100.08 ? 964  MET A SD  1 
ATOM   5712 C CE  . MET A 1 842  ? 159.120 167.808 173.968 1.00 75.81  ? 964  MET A CE  1 
ATOM   5713 N N   . VAL A 1 843  ? 156.965 167.743 179.138 1.00 66.24  ? 965  VAL A N   1 
ATOM   5714 C CA  . VAL A 1 843  ? 156.563 168.158 180.475 1.00 66.86  ? 965  VAL A CA  1 
ATOM   5715 C C   . VAL A 1 843  ? 156.615 169.671 180.600 1.00 76.16  ? 965  VAL A C   1 
ATOM   5716 O O   . VAL A 1 843  ? 155.650 170.322 181.008 1.00 85.98  ? 965  VAL A O   1 
ATOM   5717 C CB  . VAL A 1 843  ? 157.474 167.473 181.513 1.00 62.70  ? 965  VAL A CB  1 
ATOM   5718 C CG1 . VAL A 1 843  ? 157.211 168.002 182.907 1.00 70.87  ? 965  VAL A CG1 1 
ATOM   5719 C CG2 . VAL A 1 843  ? 157.260 165.992 181.472 1.00 61.19  ? 965  VAL A CG2 1 
ATOM   5720 N N   . ASN A 1 844  ? 157.751 170.221 180.212 1.00 73.04  ? 966  ASN A N   1 
ATOM   5721 C CA  . ASN A 1 844  ? 158.060 171.637 180.148 1.00 72.83  ? 966  ASN A CA  1 
ATOM   5722 C C   . ASN A 1 844  ? 159.080 171.791 179.034 1.00 82.70  ? 966  ASN A C   1 
ATOM   5723 O O   . ASN A 1 844  ? 159.365 170.825 178.323 1.00 92.65  ? 966  ASN A O   1 
ATOM   5724 C CB  . ASN A 1 844  ? 158.421 172.132 181.564 1.00 84.24  ? 966  ASN A CB  1 
ATOM   5725 C CG  . ASN A 1 844  ? 159.674 171.496 182.139 1.00 90.58  ? 966  ASN A CG  1 
ATOM   5726 O OD1 . ASN A 1 844  ? 159.672 170.283 182.325 1.00 94.51  ? 966  ASN A OD1 1 
ATOM   5727 N ND2 . ASN A 1 844  ? 160.653 172.304 182.592 1.00 94.39  ? 966  ASN A ND2 1 
ATOM   5728 N N   . GLU A 1 845  ? 159.601 173.004 178.831 1.00 89.66  ? 967  GLU A N   1 
ATOM   5729 C CA  . GLU A 1 845  ? 160.229 173.324 177.545 1.00 88.05  ? 967  GLU A CA  1 
ATOM   5730 C C   . GLU A 1 845  ? 161.655 172.788 177.423 1.00 91.28  ? 967  GLU A C   1 
ATOM   5731 O O   . GLU A 1 845  ? 162.251 172.838 176.341 1.00 96.39  ? 967  GLU A O   1 
ATOM   5732 C CB  . GLU A 1 845  ? 160.202 174.833 177.312 1.00 87.66  ? 967  GLU A CB  1 
ATOM   5733 C CG  . GLU A 1 845  ? 161.077 175.652 178.241 1.00 96.71  ? 967  GLU A CG  1 
ATOM   5734 C CD  . GLU A 1 845  ? 160.303 176.221 179.416 1.00 111.64 ? 967  GLU A CD  1 
ATOM   5735 O OE1 . GLU A 1 845  ? 159.165 175.770 179.664 1.00 114.60 ? 967  GLU A OE1 1 
ATOM   5736 O OE2 . GLU A 1 845  ? 160.811 177.155 180.067 1.00 114.84 ? 967  GLU A OE2 1 
ATOM   5737 N N   . SER A 1 846  ? 162.213 172.265 178.511 1.00 89.23  ? 968  SER A N   1 
ATOM   5738 C CA  . SER A 1 846  ? 163.502 171.595 178.440 1.00 83.94  ? 968  SER A CA  1 
ATOM   5739 C C   . SER A 1 846  ? 163.338 170.083 178.311 1.00 82.40  ? 968  SER A C   1 
ATOM   5740 O O   . SER A 1 846  ? 163.979 169.450 177.466 1.00 90.40  ? 968  SER A O   1 
ATOM   5741 C CB  . SER A 1 846  ? 164.322 171.950 179.676 1.00 93.38  ? 968  SER A CB  1 
ATOM   5742 O OG  . SER A 1 846  ? 164.670 173.322 179.671 1.00 97.25  ? 968  SER A OG  1 
ATOM   5743 N N   . VAL A 1 847  ? 162.464 169.490 179.124 1.00 74.48  ? 969  VAL A N   1 
ATOM   5744 C CA  . VAL A 1 847  ? 162.465 168.054 179.393 1.00 69.78  ? 969  VAL A CA  1 
ATOM   5745 C C   . VAL A 1 847  ? 161.375 167.367 178.582 1.00 65.20  ? 969  VAL A C   1 
ATOM   5746 O O   . VAL A 1 847  ? 160.217 167.798 178.585 1.00 77.58  ? 969  VAL A O   1 
ATOM   5747 C CB  . VAL A 1 847  ? 162.274 167.806 180.902 1.00 80.29  ? 969  VAL A CB  1 
ATOM   5748 C CG1 . VAL A 1 847  ? 162.409 166.330 181.257 1.00 79.05  ? 969  VAL A CG1 1 
ATOM   5749 C CG2 . VAL A 1 847  ? 163.250 168.647 181.692 1.00 88.12  ? 969  VAL A CG2 1 
ATOM   5750 N N   . GLY A 1 848  ? 161.743 166.291 177.889 1.00 65.29  ? 970  GLY A N   1 
ATOM   5751 C CA  . GLY A 1 848  ? 160.771 165.464 177.201 1.00 65.41  ? 970  GLY A CA  1 
ATOM   5752 C C   . GLY A 1 848  ? 160.938 164.004 177.567 1.00 68.00  ? 970  GLY A C   1 
ATOM   5753 O O   . GLY A 1 848  ? 162.007 163.570 178.005 1.00 82.21  ? 970  GLY A O   1 
ATOM   5754 N N   . TYR A 1 849  ? 159.861 163.246 177.380 1.00 59.67  ? 971  TYR A N   1 
ATOM   5755 C CA  . TYR A 1 849  ? 159.828 161.817 177.664 1.00 60.85  ? 971  TYR A CA  1 
ATOM   5756 C C   . TYR A 1 849  ? 159.373 161.082 176.416 1.00 64.85  ? 971  TYR A C   1 
ATOM   5757 O O   . TYR A 1 849  ? 158.343 161.431 175.833 1.00 76.92  ? 971  TYR A O   1 
ATOM   5758 C CB  . TYR A 1 849  ? 158.878 161.492 178.820 1.00 63.71  ? 971  TYR A CB  1 
ATOM   5759 C CG  . TYR A 1 849  ? 159.409 161.802 180.197 1.00 62.35  ? 971  TYR A CG  1 
ATOM   5760 C CD1 . TYR A 1 849  ? 159.408 163.113 180.680 1.00 64.53  ? 971  TYR A CD1 1 
ATOM   5761 C CD2 . TYR A 1 849  ? 159.893 160.783 181.021 1.00 70.99  ? 971  TYR A CD2 1 
ATOM   5762 C CE1 . TYR A 1 849  ? 159.890 163.410 181.946 1.00 67.77  ? 971  TYR A CE1 1 
ATOM   5763 C CE2 . TYR A 1 849  ? 160.377 161.068 182.296 1.00 76.95  ? 971  TYR A CE2 1 
ATOM   5764 C CZ  . TYR A 1 849  ? 160.369 162.384 182.743 1.00 74.46  ? 971  TYR A CZ  1 
ATOM   5765 O OH  . TYR A 1 849  ? 160.843 162.684 183.994 1.00 86.94  ? 971  TYR A OH  1 
ATOM   5766 N N   . TYR A 1 850  ? 160.120 160.061 176.015 1.00 58.65  ? 972  TYR A N   1 
ATOM   5767 C CA  . TYR A 1 850  ? 159.774 159.280 174.839 1.00 62.57  ? 972  TYR A CA  1 
ATOM   5768 C C   . TYR A 1 850  ? 160.000 157.804 175.114 1.00 64.72  ? 972  TYR A C   1 
ATOM   5769 O O   . TYR A 1 850  ? 160.807 157.429 175.966 1.00 63.55  ? 972  TYR A O   1 
ATOM   5770 C CB  . TYR A 1 850  ? 160.573 159.719 173.590 1.00 64.95  ? 972  TYR A CB  1 
ATOM   5771 C CG  . TYR A 1 850  ? 162.082 159.538 173.626 1.00 67.06  ? 972  TYR A CG  1 
ATOM   5772 C CD1 . TYR A 1 850  ? 162.905 160.479 174.255 1.00 68.64  ? 972  TYR A CD1 1 
ATOM   5773 C CD2 . TYR A 1 850  ? 162.686 158.453 172.984 1.00 64.41  ? 972  TYR A CD2 1 
ATOM   5774 C CE1 . TYR A 1 850  ? 164.286 160.335 174.266 1.00 66.16  ? 972  TYR A CE1 1 
ATOM   5775 C CE2 . TYR A 1 850  ? 164.072 158.295 172.988 1.00 66.75  ? 972  TYR A CE2 1 
ATOM   5776 C CZ  . TYR A 1 850  ? 164.857 159.245 173.628 1.00 72.23  ? 972  TYR A CZ  1 
ATOM   5777 O OH  . TYR A 1 850  ? 166.222 159.106 173.651 1.00 81.64  ? 972  TYR A OH  1 
ATOM   5778 N N   . VAL A 1 851  ? 159.272 156.968 174.382 1.00 67.90  ? 973  VAL A N   1 
ATOM   5779 C CA  . VAL A 1 851  ? 159.370 155.522 174.517 1.00 65.49  ? 973  VAL A CA  1 
ATOM   5780 C C   . VAL A 1 851  ? 160.137 154.983 173.319 1.00 74.12  ? 973  VAL A C   1 
ATOM   5781 O O   . VAL A 1 851  ? 159.659 155.046 172.180 1.00 78.48  ? 973  VAL A O   1 
ATOM   5782 C CB  . VAL A 1 851  ? 157.990 154.863 174.641 1.00 66.55  ? 973  VAL A CB  1 
ATOM   5783 C CG1 . VAL A 1 851  ? 158.132 153.361 174.675 1.00 67.11  ? 973  VAL A CG1 1 
ATOM   5784 C CG2 . VAL A 1 851  ? 157.300 155.332 175.898 1.00 65.29  ? 973  VAL A CG2 1 
ATOM   5785 N N   . THR A 1 852  ? 161.332 154.475 173.584 1.00 77.51  ? 974  THR A N   1 
ATOM   5786 C CA  . THR A 1 852  ? 162.155 153.785 172.606 1.00 69.33  ? 974  THR A CA  1 
ATOM   5787 C C   . THR A 1 852  ? 161.497 152.436 172.288 1.00 75.02  ? 974  THR A C   1 
ATOM   5788 O O   . THR A 1 852  ? 160.933 151.782 173.168 1.00 87.02  ? 974  THR A O   1 
ATOM   5789 C CB  . THR A 1 852  ? 163.581 153.693 173.185 1.00 72.29  ? 974  THR A CB  1 
ATOM   5790 O OG1 . THR A 1 852  ? 164.180 154.993 173.130 1.00 83.17  ? 974  THR A OG1 1 
ATOM   5791 C CG2 . THR A 1 852  ? 164.514 152.746 172.472 1.00 78.04  ? 974  THR A CG2 1 
ATOM   5792 N N   . GLY A 1 853  ? 161.548 152.032 171.004 1.00 73.37  ? 975  GLY A N   1 
ATOM   5793 C CA  . GLY A 1 853  ? 160.643 151.010 170.485 1.00 75.81  ? 975  GLY A CA  1 
ATOM   5794 C C   . GLY A 1 853  ? 160.916 149.572 170.906 1.00 82.31  ? 975  GLY A C   1 
ATOM   5795 O O   . GLY A 1 853  ? 160.149 148.672 170.553 1.00 81.51  ? 975  GLY A O   1 
ATOM   5796 N N   . ASP A 1 854  ? 161.992 149.323 171.658 1.00 76.16  ? 976  ASP A N   1 
ATOM   5797 C CA  . ASP A 1 854  ? 162.124 148.024 172.311 1.00 80.37  ? 976  ASP A CA  1 
ATOM   5798 C C   . ASP A 1 854  ? 161.406 147.954 173.659 1.00 87.97  ? 976  ASP A C   1 
ATOM   5799 O O   . ASP A 1 854  ? 161.383 146.883 174.273 1.00 94.69  ? 976  ASP A O   1 
ATOM   5800 C CB  . ASP A 1 854  ? 163.611 147.632 172.436 1.00 85.31  ? 976  ASP A CB  1 
ATOM   5801 C CG  . ASP A 1 854  ? 164.463 148.615 173.261 1.00 87.46  ? 976  ASP A CG  1 
ATOM   5802 O OD1 . ASP A 1 854  ? 164.005 149.675 173.726 1.00 84.19  ? 976  ASP A OD1 1 
ATOM   5803 O OD2 . ASP A 1 854  ? 165.658 148.303 173.445 1.00 89.58  ? 976  ASP A OD2 1 
ATOM   5804 N N   . GLY A 1 855  ? 160.837 149.062 174.124 1.00 83.71  ? 977  GLY A N   1 
ATOM   5805 C CA  . GLY A 1 855  ? 160.162 149.121 175.399 1.00 76.61  ? 977  GLY A CA  1 
ATOM   5806 C C   . GLY A 1 855  ? 160.772 150.062 176.408 1.00 74.31  ? 977  GLY A C   1 
ATOM   5807 O O   . GLY A 1 855  ? 160.221 150.205 177.503 1.00 79.96  ? 977  GLY A O   1 
ATOM   5808 N N   . LEU A 1 856  ? 161.882 150.711 176.079 1.00 70.59  ? 978  LEU A N   1 
ATOM   5809 C CA  . LEU A 1 856  ? 162.566 151.570 177.030 1.00 67.04  ? 978  LEU A CA  1 
ATOM   5810 C C   . LEU A 1 856  ? 161.947 152.960 177.050 1.00 70.09  ? 978  LEU A C   1 
ATOM   5811 O O   . LEU A 1 856  ? 161.675 153.550 176.006 1.00 81.39  ? 978  LEU A O   1 
ATOM   5812 C CB  . LEU A 1 856  ? 164.050 151.672 176.688 1.00 76.15  ? 978  LEU A CB  1 
ATOM   5813 C CG  . LEU A 1 856  ? 164.921 150.480 177.081 1.00 79.54  ? 978  LEU A CG  1 
ATOM   5814 C CD1 . LEU A 1 856  ? 166.250 150.542 176.357 1.00 80.93  ? 978  LEU A CD1 1 
ATOM   5815 C CD2 . LEU A 1 856  ? 165.133 150.457 178.573 1.00 76.30  ? 978  LEU A CD2 1 
ATOM   5816 N N   . LEU A 1 857  ? 161.729 153.487 178.252 1.00 67.32  ? 979  LEU A N   1 
ATOM   5817 C CA  . LEU A 1 857  ? 161.250 154.852 178.431 1.00 65.64  ? 979  LEU A CA  1 
ATOM   5818 C C   . LEU A 1 857  ? 162.433 155.736 178.787 1.00 67.33  ? 979  LEU A C   1 
ATOM   5819 O O   . LEU A 1 857  ? 163.121 155.486 179.781 1.00 73.84  ? 979  LEU A O   1 
ATOM   5820 C CB  . LEU A 1 857  ? 160.176 154.941 179.513 1.00 65.62  ? 979  LEU A CB  1 
ATOM   5821 C CG  . LEU A 1 857  ? 159.801 156.354 179.964 1.00 55.28  ? 979  LEU A CG  1 
ATOM   5822 C CD1 . LEU A 1 857  ? 158.833 156.980 178.993 1.00 60.92  ? 979  LEU A CD1 1 
ATOM   5823 C CD2 . LEU A 1 857  ? 159.205 156.340 181.349 1.00 59.44  ? 979  LEU A CD2 1 
ATOM   5824 N N   . HIS A 1 858  ? 162.664 156.765 177.981 1.00 66.00  ? 980  HIS A N   1 
ATOM   5825 C CA  . HIS A 1 858  ? 163.813 157.636 178.142 1.00 63.49  ? 980  HIS A CA  1 
ATOM   5826 C C   . HIS A 1 858  ? 163.385 159.027 178.581 1.00 69.28  ? 980  HIS A C   1 
ATOM   5827 O O   . HIS A 1 858  ? 162.200 159.309 178.766 1.00 77.50  ? 980  HIS A O   1 
ATOM   5828 C CB  . HIS A 1 858  ? 164.611 157.746 176.853 1.00 68.06  ? 980  HIS A CB  1 
ATOM   5829 C CG  . HIS A 1 858  ? 165.465 156.556 176.565 1.00 69.36  ? 980  HIS A CG  1 
ATOM   5830 N ND1 . HIS A 1 858  ? 165.022 155.479 175.831 1.00 67.08  ? 980  HIS A ND1 1 
ATOM   5831 C CD2 . HIS A 1 858  ? 166.747 156.281 176.900 1.00 73.43  ? 980  HIS A CD2 1 
ATOM   5832 C CE1 . HIS A 1 858  ? 165.990 154.587 175.736 1.00 75.23  ? 980  HIS A CE1 1 
ATOM   5833 N NE2 . HIS A 1 858  ? 167.048 155.050 176.376 1.00 81.46  ? 980  HIS A NE2 1 
ATOM   5834 N N   . CYS A 1 859  ? 164.383 159.889 178.729 1.00 74.78  ? 981  CYS A N   1 
ATOM   5835 C CA  . CYS A 1 859  ? 164.245 161.224 179.286 1.00 73.87  ? 981  CYS A CA  1 
ATOM   5836 C C   . CYS A 1 859  ? 165.449 162.054 178.881 1.00 80.58  ? 981  CYS A C   1 
ATOM   5837 O O   . CYS A 1 859  ? 166.581 161.732 179.254 1.00 93.33  ? 981  CYS A O   1 
ATOM   5838 C CB  . CYS A 1 859  ? 164.140 161.161 180.801 1.00 84.19  ? 981  CYS A CB  1 
ATOM   5839 S SG  . CYS A 1 859  ? 164.025 162.731 181.635 1.00 105.41 ? 981  CYS A SG  1 
ATOM   5840 N N   . ILE A 1 860  ? 165.208 163.119 178.126 1.00 72.54  ? 982  ILE A N   1 
ATOM   5841 C CA  . ILE A 1 860  ? 166.271 163.985 177.639 1.00 79.49  ? 982  ILE A CA  1 
ATOM   5842 C C   . ILE A 1 860  ? 165.915 165.434 177.956 1.00 78.32  ? 982  ILE A C   1 
ATOM   5843 O O   . ILE A 1 860  ? 164.765 165.856 177.792 1.00 81.53  ? 982  ILE A O   1 
ATOM   5844 C CB  . ILE A 1 860  ? 166.549 163.734 176.135 1.00 82.03  ? 982  ILE A CB  1 
ATOM   5845 C CG1 . ILE A 1 860  ? 167.692 164.603 175.589 1.00 86.55  ? 982  ILE A CG1 1 
ATOM   5846 C CG2 . ILE A 1 860  ? 165.291 163.752 175.275 1.00 76.09  ? 982  ILE A CG2 1 
ATOM   5847 C CD1 . ILE A 1 860  ? 168.172 164.183 174.223 1.00 81.98  ? 982  ILE A CD1 1 
ATOM   5848 N N   . ASN A 1 861  ? 166.878 166.164 178.509 1.00 76.99  ? 983  ASN A N   1 
ATOM   5849 C CA  . ASN A 1 861  ? 166.805 167.618 178.588 1.00 82.52  ? 983  ASN A CA  1 
ATOM   5850 C C   . ASN A 1 861  ? 167.463 168.135 177.318 1.00 95.83  ? 983  ASN A C   1 
ATOM   5851 O O   . ASN A 1 861  ? 168.653 167.911 177.086 1.00 106.23 ? 983  ASN A O   1 
ATOM   5852 C CB  . ASN A 1 861  ? 167.483 168.128 179.855 1.00 87.10  ? 983  ASN A CB  1 
ATOM   5853 C CG  . ASN A 1 861  ? 167.107 169.562 180.196 1.00 95.53  ? 983  ASN A CG  1 
ATOM   5854 O OD1 . ASN A 1 861  ? 167.323 170.485 179.415 1.00 105.02 ? 983  ASN A OD1 1 
ATOM   5855 N ND2 . ASN A 1 861  ? 166.542 169.751 181.373 1.00 91.78  ? 983  ASN A ND2 1 
ATOM   5856 N N   . LEU A 1 862  ? 166.678 168.816 176.482 1.00 87.44  ? 984  LEU A N   1 
ATOM   5857 C CA  . LEU A 1 862  ? 167.186 169.289 175.201 1.00 89.90  ? 984  LEU A CA  1 
ATOM   5858 C C   . LEU A 1 862  ? 168.049 170.534 175.375 1.00 98.25  ? 984  LEU A C   1 
ATOM   5859 O O   . LEU A 1 862  ? 168.927 170.815 174.551 1.00 104.92 ? 984  LEU A O   1 
ATOM   5860 C CB  . LEU A 1 862  ? 166.022 169.567 174.255 1.00 89.86  ? 984  LEU A CB  1 
ATOM   5861 C CG  . LEU A 1 862  ? 164.939 168.492 174.228 1.00 85.39  ? 984  LEU A CG  1 
ATOM   5862 C CD1 . LEU A 1 862  ? 163.675 169.042 173.606 1.00 83.56  ? 984  LEU A CD1 1 
ATOM   5863 C CD2 . LEU A 1 862  ? 165.423 167.282 173.462 1.00 89.38  ? 984  LEU A CD2 1 
ATOM   5864 N N   . VAL A 1 863  ? 167.819 171.288 176.451 1.00 99.04  ? 985  VAL A N   1 
ATOM   5865 C CA  . VAL A 1 863  ? 168.475 172.582 176.599 1.00 106.07 ? 985  VAL A CA  1 
ATOM   5866 C C   . VAL A 1 863  ? 169.817 172.424 177.310 1.00 109.01 ? 985  VAL A C   1 
ATOM   5867 O O   . VAL A 1 863  ? 170.876 172.694 176.733 1.00 111.90 ? 985  VAL A O   1 
ATOM   5868 C CB  . VAL A 1 863  ? 167.542 173.561 177.337 1.00 105.59 ? 985  VAL A CB  1 
ATOM   5869 C CG1 . VAL A 1 863  ? 168.227 174.889 177.599 1.00 111.19 ? 985  VAL A CG1 1 
ATOM   5870 C CG2 . VAL A 1 863  ? 166.272 173.781 176.535 1.00 98.64  ? 985  VAL A CG2 1 
ATOM   5871 N N   . HIS A 1 864  ? 169.797 171.968 178.563 1.00 109.82 ? 986  HIS A N   1 
ATOM   5872 C CA  . HIS A 1 864  ? 171.000 171.810 179.379 1.00 123.58 ? 986  HIS A CA  1 
ATOM   5873 C C   . HIS A 1 864  ? 171.017 170.383 179.917 1.00 120.87 ? 986  HIS A C   1 
ATOM   5874 O O   . HIS A 1 864  ? 170.201 170.036 180.776 1.00 123.03 ? 986  HIS A O   1 
ATOM   5875 C CB  . HIS A 1 864  ? 171.013 172.797 180.539 1.00 126.81 ? 986  HIS A CB  1 
ATOM   5876 C CG  . HIS A 1 864  ? 171.173 174.236 180.161 1.00 135.54 ? 986  HIS A CG  1 
ATOM   5877 N ND1 . HIS A 1 864  ? 171.013 175.253 181.078 1.00 138.35 ? 986  HIS A ND1 1 
ATOM   5878 C CD2 . HIS A 1 864  ? 171.535 174.833 179.000 1.00 136.70 ? 986  HIS A CD2 1 
ATOM   5879 C CE1 . HIS A 1 864  ? 171.222 176.415 180.486 1.00 139.74 ? 986  HIS A CE1 1 
ATOM   5880 N NE2 . HIS A 1 864  ? 171.540 176.187 179.224 1.00 141.06 ? 986  HIS A NE2 1 
ATOM   5881 N N   . SER A 1 865  ? 171.963 169.564 179.454 1.00 117.38 ? 987  SER A N   1 
ATOM   5882 C CA  . SER A 1 865  ? 171.821 168.116 179.589 1.00 120.52 ? 987  SER A CA  1 
ATOM   5883 C C   . SER A 1 865  ? 172.309 167.542 180.924 1.00 129.14 ? 987  SER A C   1 
ATOM   5884 O O   . SER A 1 865  ? 172.117 166.344 181.159 1.00 131.45 ? 987  SER A O   1 
ATOM   5885 C CB  . SER A 1 865  ? 172.558 167.423 178.441 1.00 121.39 ? 987  SER A CB  1 
ATOM   5886 O OG  . SER A 1 865  ? 172.331 166.024 178.454 1.00 129.90 ? 987  SER A OG  1 
ATOM   5887 N N   . GLN A 1 866  ? 172.934 168.334 181.805 1.00 130.83 ? 988  GLN A N   1 
ATOM   5888 C CA  . GLN A 1 866  ? 173.486 167.741 183.027 1.00 133.53 ? 988  GLN A CA  1 
ATOM   5889 C C   . GLN A 1 866  ? 172.468 167.764 184.170 1.00 136.13 ? 988  GLN A C   1 
ATOM   5890 O O   . GLN A 1 866  ? 172.721 167.227 185.255 1.00 137.27 ? 988  GLN A O   1 
ATOM   5891 C CB  . GLN A 1 866  ? 174.818 168.423 183.391 1.00 129.08 ? 988  GLN A CB  1 
ATOM   5892 C CG  . GLN A 1 866  ? 174.830 169.929 183.746 1.00 135.35 ? 988  GLN A CG  1 
ATOM   5893 C CD  . GLN A 1 866  ? 174.513 170.233 185.205 1.00 141.44 ? 988  GLN A CD  1 
ATOM   5894 O OE1 . GLN A 1 866  ? 174.804 169.429 186.094 1.00 139.50 ? 988  GLN A OE1 1 
ATOM   5895 N NE2 . GLN A 1 866  ? 173.896 171.384 185.452 1.00 140.72 ? 988  GLN A NE2 1 
ATOM   5896 N N   . TRP A 1 867  ? 171.317 168.383 183.941 1.00 134.03 ? 989  TRP A N   1 
ATOM   5897 C CA  . TRP A 1 867  ? 170.226 168.465 184.903 1.00 131.04 ? 989  TRP A CA  1 
ATOM   5898 C C   . TRP A 1 867  ? 168.876 168.496 184.198 1.00 126.28 ? 989  TRP A C   1 
ATOM   5899 O O   . TRP A 1 867  ? 168.785 168.656 182.980 1.00 123.68 ? 989  TRP A O   1 
ATOM   5900 C CB  . TRP A 1 867  ? 170.370 169.667 185.872 1.00 134.84 ? 989  TRP A CB  1 
ATOM   5901 C CG  . TRP A 1 867  ? 170.182 171.034 185.241 1.00 141.68 ? 989  TRP A CG  1 
ATOM   5902 C CD1 . TRP A 1 867  ? 170.891 171.549 184.193 1.00 139.21 ? 989  TRP A CD1 1 
ATOM   5903 C CD2 . TRP A 1 867  ? 169.102 171.961 185.458 1.00 142.51 ? 989  TRP A CD2 1 
ATOM   5904 N NE1 . TRP A 1 867  ? 170.426 172.776 183.855 1.00 137.91 ? 989  TRP A NE1 1 
ATOM   5905 C CE2 . TRP A 1 867  ? 169.309 173.051 184.583 1.00 140.94 ? 989  TRP A CE2 1 
ATOM   5906 C CE3 . TRP A 1 867  ? 168.016 172.002 186.333 1.00 136.39 ? 989  TRP A CE3 1 
ATOM   5907 C CZ2 . TRP A 1 867  ? 168.473 174.166 184.556 1.00 139.18 ? 989  TRP A CZ2 1 
ATOM   5908 C CZ3 . TRP A 1 867  ? 167.179 173.117 186.300 1.00 135.55 ? 989  TRP A CZ3 1 
ATOM   5909 C CH2 . TRP A 1 867  ? 167.427 174.180 185.416 1.00 137.41 ? 989  TRP A CH2 1 
ATOM   5910 N N   . GLY A 1 868  ? 167.823 168.330 185.000 1.00 122.54 ? 990  GLY A N   1 
ATOM   5911 C CA  . GLY A 1 868  ? 166.454 168.398 184.528 1.00 120.49 ? 990  GLY A CA  1 
ATOM   5912 C C   . GLY A 1 868  ? 165.666 167.102 184.547 1.00 113.65 ? 990  GLY A C   1 
ATOM   5913 O O   . GLY A 1 868  ? 164.433 167.119 184.477 1.00 111.55 ? 990  GLY A O   1 
ATOM   5914 N N   . CYS A 1 869  ? 166.351 165.972 184.666 1.00 111.01 ? 991  CYS A N   1 
ATOM   5915 C CA  . CYS A 1 869  ? 165.686 164.677 184.590 1.00 105.33 ? 991  CYS A CA  1 
ATOM   5916 C C   . CYS A 1 869  ? 165.825 163.907 185.897 1.00 106.10 ? 991  CYS A C   1 
ATOM   5917 O O   . CYS A 1 869  ? 166.951 163.745 186.392 1.00 109.84 ? 991  CYS A O   1 
ATOM   5918 C CB  . CYS A 1 869  ? 166.242 163.857 183.430 1.00 99.65  ? 991  CYS A CB  1 
ATOM   5919 S SG  . CYS A 1 869  ? 165.297 162.372 183.173 1.00 123.89 ? 991  CYS A SG  1 
ATOM   5920 N N   . PRO A 1 870  ? 164.727 163.415 186.487 1.00 101.29 ? 992  PRO A N   1 
ATOM   5921 C CA  . PRO A 1 870  ? 164.843 162.778 187.809 1.00 104.21 ? 992  PRO A CA  1 
ATOM   5922 C C   . PRO A 1 870  ? 165.347 161.347 187.771 1.00 108.97 ? 992  PRO A C   1 
ATOM   5923 O O   . PRO A 1 870  ? 165.756 160.823 188.813 1.00 108.85 ? 992  PRO A O   1 
ATOM   5924 C CB  . PRO A 1 870  ? 163.410 162.852 188.350 1.00 99.09  ? 992  PRO A CB  1 
ATOM   5925 C CG  . PRO A 1 870  ? 162.566 162.832 187.135 1.00 98.81  ? 992  PRO A CG  1 
ATOM   5926 C CD  . PRO A 1 870  ? 163.319 163.606 186.097 1.00 98.51  ? 992  PRO A CD  1 
ATOM   5927 N N   . ILE A 1 871  ? 165.320 160.687 186.617 1.00 109.55 ? 993  ILE A N   1 
ATOM   5928 C CA  . ILE A 1 871  ? 165.729 159.290 186.535 1.00 104.99 ? 993  ILE A CA  1 
ATOM   5929 C C   . ILE A 1 871  ? 167.112 159.209 185.896 1.00 111.13 ? 993  ILE A C   1 
ATOM   5930 O O   . ILE A 1 871  ? 167.412 159.906 184.922 1.00 114.62 ? 993  ILE A O   1 
ATOM   5931 C CB  . ILE A 1 871  ? 164.698 158.435 185.787 1.00 98.54  ? 993  ILE A CB  1 
ATOM   5932 C CG1 . ILE A 1 871  ? 164.217 159.091 184.494 1.00 99.47  ? 993  ILE A CG1 1 
ATOM   5933 C CG2 . ILE A 1 871  ? 163.504 158.277 186.656 1.00 92.83  ? 993  ILE A CG2 1 
ATOM   5934 C CD1 . ILE A 1 871  ? 163.444 158.162 183.586 1.00 95.98  ? 993  ILE A CD1 1 
ATOM   5935 N N   . SER A 1 872  ? 167.981 158.387 186.484 1.00 106.90 ? 994  SER A N   1 
ATOM   5936 C CA  . SER A 1 872  ? 169.323 158.230 185.938 1.00 111.82 ? 994  SER A CA  1 
ATOM   5937 C C   . SER A 1 872  ? 169.355 157.167 184.849 1.00 114.20 ? 994  SER A C   1 
ATOM   5938 O O   . SER A 1 872  ? 170.135 157.269 183.896 1.00 115.30 ? 994  SER A O   1 
ATOM   5939 C CB  . SER A 1 872  ? 170.306 157.887 187.055 1.00 111.95 ? 994  SER A CB  1 
ATOM   5940 O OG  . SER A 1 872  ? 170.218 158.823 188.114 1.00 109.47 ? 994  SER A OG  1 
ATOM   5941 N N   . GLU A 1 873  ? 168.517 156.144 184.971 1.00 110.90 ? 995  GLU A N   1 
ATOM   5942 C CA  . GLU A 1 873  ? 168.517 155.015 184.059 1.00 102.86 ? 995  GLU A CA  1 
ATOM   5943 C C   . GLU A 1 873  ? 167.229 154.974 183.236 1.00 102.34 ? 995  GLU A C   1 
ATOM   5944 O O   . GLU A 1 873  ? 166.204 155.523 183.653 1.00 105.72 ? 995  GLU A O   1 
ATOM   5945 C CB  . GLU A 1 873  ? 168.688 153.699 184.838 1.00 106.78 ? 995  GLU A CB  1 
ATOM   5946 C CG  . GLU A 1 873  ? 167.552 153.344 185.800 1.00 113.27 ? 995  GLU A CG  1 
ATOM   5947 C CD  . GLU A 1 873  ? 167.778 153.853 187.214 1.00 121.10 ? 995  GLU A CD  1 
ATOM   5948 O OE1 . GLU A 1 873  ? 168.710 154.655 187.430 1.00 115.43 ? 995  GLU A OE1 1 
ATOM   5949 O OE2 . GLU A 1 873  ? 167.013 153.452 188.114 1.00 125.76 ? 995  GLU A OE2 1 
ATOM   5950 N N   . PRO A 1 874  ? 167.262 154.391 182.035 1.00 96.30  ? 996  PRO A N   1 
ATOM   5951 C CA  . PRO A 1 874  ? 166.010 154.124 181.317 1.00 87.73  ? 996  PRO A CA  1 
ATOM   5952 C C   . PRO A 1 874  ? 165.219 152.994 181.961 1.00 89.62  ? 996  PRO A C   1 
ATOM   5953 O O   . PRO A 1 874  ? 165.765 152.160 182.686 1.00 91.26  ? 996  PRO A O   1 
ATOM   5954 C CB  . PRO A 1 874  ? 166.481 153.754 179.908 1.00 77.88  ? 996  PRO A CB  1 
ATOM   5955 C CG  . PRO A 1 874  ? 167.811 154.390 179.785 1.00 85.70  ? 996  PRO A CG  1 
ATOM   5956 C CD  . PRO A 1 874  ? 168.424 154.261 181.139 1.00 92.01  ? 996  PRO A CD  1 
ATOM   5957 N N   . LEU A 1 875  ? 163.919 152.979 181.686 1.00 82.97  ? 997  LEU A N   1 
ATOM   5958 C CA  . LEU A 1 875  ? 162.975 152.075 182.326 1.00 76.94  ? 997  LEU A CA  1 
ATOM   5959 C C   . LEU A 1 875  ? 162.444 151.071 181.319 1.00 75.66  ? 997  LEU A C   1 
ATOM   5960 O O   . LEU A 1 875  ? 161.847 151.462 180.315 1.00 77.04  ? 997  LEU A O   1 
ATOM   5961 C CB  . LEU A 1 875  ? 161.807 152.863 182.900 1.00 71.45  ? 997  LEU A CB  1 
ATOM   5962 C CG  . LEU A 1 875  ? 162.094 153.818 184.039 1.00 76.58  ? 997  LEU A CG  1 
ATOM   5963 C CD1 . LEU A 1 875  ? 160.825 154.540 184.287 1.00 67.55  ? 997  LEU A CD1 1 
ATOM   5964 C CD2 . LEU A 1 875  ? 162.523 153.055 185.275 1.00 81.66  ? 997  LEU A CD2 1 
ATOM   5965 N N   . GLN A 1 876  ? 162.612 149.788 181.613 1.00 71.42  ? 998  GLN A N   1 
ATOM   5966 C CA  . GLN A 1 876  ? 162.180 148.735 180.711 1.00 69.49  ? 998  GLN A CA  1 
ATOM   5967 C C   . GLN A 1 876  ? 160.668 148.537 180.781 1.00 69.23  ? 998  GLN A C   1 
ATOM   5968 O O   . GLN A 1 876  ? 160.021 148.892 181.771 1.00 74.66  ? 998  GLN A O   1 
ATOM   5969 C CB  . GLN A 1 876  ? 162.895 147.427 181.039 1.00 76.69  ? 998  GLN A CB  1 
ATOM   5970 C CG  . GLN A 1 876  ? 164.365 147.408 180.696 1.00 81.27  ? 998  GLN A CG  1 
ATOM   5971 C CD  . GLN A 1 876  ? 165.192 146.726 181.759 1.00 94.24  ? 998  GLN A CD  1 
ATOM   5972 O OE1 . GLN A 1 876  ? 165.193 145.501 181.867 1.00 95.65  ? 998  GLN A OE1 1 
ATOM   5973 N NE2 . GLN A 1 876  ? 165.898 147.516 182.557 1.00 91.45  ? 998  GLN A NE2 1 
ATOM   5974 N N   . HIS A 1 877  ? 160.130 147.982 179.682 1.00 65.47  ? 999  HIS A N   1 
ATOM   5975 C CA  . HIS A 1 877  ? 158.763 147.453 179.518 1.00 65.57  ? 999  HIS A CA  1 
ATOM   5976 C C   . HIS A 1 877  ? 157.689 148.530 179.698 1.00 66.76  ? 999  HIS A C   1 
ATOM   5977 O O   . HIS A 1 877  ? 156.766 148.401 180.501 1.00 75.03  ? 999  HIS A O   1 
ATOM   5978 C CB  . HIS A 1 877  ? 158.510 146.258 180.446 1.00 71.96  ? 999  HIS A CB  1 
ATOM   5979 C CG  . HIS A 1 877  ? 159.655 145.298 180.524 1.00 80.49  ? 999  HIS A CG  1 
ATOM   5980 N ND1 . HIS A 1 877  ? 160.374 145.096 181.682 1.00 81.64  ? 999  HIS A ND1 1 
ATOM   5981 C CD2 . HIS A 1 877  ? 160.207 144.487 179.591 1.00 83.19  ? 999  HIS A CD2 1 
ATOM   5982 C CE1 . HIS A 1 877  ? 161.325 144.209 181.458 1.00 80.14  ? 999  HIS A CE1 1 
ATOM   5983 N NE2 . HIS A 1 877  ? 161.242 143.819 180.198 1.00 87.67  ? 999  HIS A NE2 1 
ATOM   5984 N N   . VAL A 1 878  ? 157.831 149.605 178.927 1.00 62.90  ? 1000 VAL A N   1 
ATOM   5985 C CA  . VAL A 1 878  ? 156.915 150.740 178.944 1.00 54.63  ? 1000 VAL A CA  1 
ATOM   5986 C C   . VAL A 1 878  ? 156.283 150.840 177.561 1.00 64.12  ? 1000 VAL A C   1 
ATOM   5987 O O   . VAL A 1 878  ? 156.994 150.799 176.553 1.00 76.04  ? 1000 VAL A O   1 
ATOM   5988 C CB  . VAL A 1 878  ? 157.651 152.042 179.329 1.00 56.01  ? 1000 VAL A CB  1 
ATOM   5989 C CG1 . VAL A 1 878  ? 156.742 153.252 179.267 1.00 58.69  ? 1000 VAL A CG1 1 
ATOM   5990 C CG2 . VAL A 1 878  ? 158.230 151.930 180.727 1.00 54.50  ? 1000 VAL A CG2 1 
ATOM   5991 N N   . GLY A 1 879  ? 154.954 150.929 177.507 1.00 61.40  ? 1001 GLY A N   1 
ATOM   5992 C CA  . GLY A 1 879  ? 154.265 150.985 176.232 1.00 62.48  ? 1001 GLY A CA  1 
ATOM   5993 C C   . GLY A 1 879  ? 154.165 152.366 175.617 1.00 69.13  ? 1001 GLY A C   1 
ATOM   5994 O O   . GLY A 1 879  ? 154.632 152.583 174.497 1.00 82.41  ? 1001 GLY A O   1 
ATOM   5995 N N   . SER A 1 880  ? 153.555 153.307 176.332 1.00 61.87  ? 1002 SER A N   1 
ATOM   5996 C CA  . SER A 1 880  ? 153.436 154.683 175.874 1.00 66.51  ? 1002 SER A CA  1 
ATOM   5997 C C   . SER A 1 880  ? 153.537 155.593 177.083 1.00 62.73  ? 1002 SER A C   1 
ATOM   5998 O O   . SER A 1 880  ? 153.544 155.131 178.220 1.00 66.54  ? 1002 SER A O   1 
ATOM   5999 C CB  . SER A 1 880  ? 152.121 154.926 175.132 1.00 68.92  ? 1002 SER A CB  1 
ATOM   6000 O OG  . SER A 1 880  ? 151.038 154.936 176.039 1.00 71.02  ? 1002 SER A OG  1 
ATOM   6001 N N   . VAL A 1 881  ? 153.618 156.898 176.838 1.00 61.20  ? 1003 VAL A N   1 
ATOM   6002 C CA  . VAL A 1 881  ? 153.764 157.877 177.908 1.00 54.68  ? 1003 VAL A CA  1 
ATOM   6003 C C   . VAL A 1 881  ? 152.921 159.110 177.569 1.00 65.98  ? 1003 VAL A C   1 
ATOM   6004 O O   . VAL A 1 881  ? 152.794 159.490 176.399 1.00 77.76  ? 1003 VAL A O   1 
ATOM   6005 C CB  . VAL A 1 881  ? 155.271 158.181 178.162 1.00 58.01  ? 1003 VAL A CB  1 
ATOM   6006 C CG1 . VAL A 1 881  ? 155.995 158.768 176.945 1.00 60.38  ? 1003 VAL A CG1 1 
ATOM   6007 C CG2 . VAL A 1 881  ? 155.497 159.029 179.399 1.00 60.95  ? 1003 VAL A CG2 1 
ATOM   6008 N N   . THR A 1 882  ? 152.237 159.659 178.577 1.00 60.51  ? 1004 THR A N   1 
ATOM   6009 C CA  . THR A 1 882  ? 151.519 160.925 178.455 1.00 61.18  ? 1004 THR A CA  1 
ATOM   6010 C C   . THR A 1 882  ? 151.875 161.818 179.629 1.00 59.02  ? 1004 THR A C   1 
ATOM   6011 O O   . THR A 1 882  ? 152.454 161.354 180.613 1.00 65.83  ? 1004 THR A O   1 
ATOM   6012 C CB  . THR A 1 882  ? 149.992 160.749 178.411 1.00 66.39  ? 1004 THR A CB  1 
ATOM   6013 O OG1 . THR A 1 882  ? 149.549 159.989 179.540 1.00 65.19  ? 1004 THR A OG1 1 
ATOM   6014 C CG2 . THR A 1 882  ? 149.518 160.118 177.115 1.00 60.60  ? 1004 THR A CG2 1 
ATOM   6015 N N   . TYR A 1 883  ? 151.525 163.095 179.518 1.00 61.99  ? 1005 TYR A N   1 
ATOM   6016 C CA  . TYR A 1 883  ? 151.701 164.067 180.584 1.00 60.43  ? 1005 TYR A CA  1 
ATOM   6017 C C   . TYR A 1 883  ? 150.393 164.806 180.816 1.00 70.63  ? 1005 TYR A C   1 
ATOM   6018 O O   . TYR A 1 883  ? 149.712 165.196 179.864 1.00 77.42  ? 1005 TYR A O   1 
ATOM   6019 C CB  . TYR A 1 883  ? 152.805 165.067 180.236 1.00 58.52  ? 1005 TYR A CB  1 
ATOM   6020 C CG  . TYR A 1 883  ? 153.033 166.147 181.266 1.00 59.96  ? 1005 TYR A CG  1 
ATOM   6021 C CD1 . TYR A 1 883  ? 153.415 165.823 182.569 1.00 62.56  ? 1005 TYR A CD1 1 
ATOM   6022 C CD2 . TYR A 1 883  ? 152.867 167.494 180.933 1.00 63.62  ? 1005 TYR A CD2 1 
ATOM   6023 C CE1 . TYR A 1 883  ? 153.632 166.815 183.520 1.00 62.25  ? 1005 TYR A CE1 1 
ATOM   6024 C CE2 . TYR A 1 883  ? 153.083 168.494 181.872 1.00 66.59  ? 1005 TYR A CE2 1 
ATOM   6025 C CZ  . TYR A 1 883  ? 153.463 168.143 183.158 1.00 64.94  ? 1005 TYR A CZ  1 
ATOM   6026 O OH  . TYR A 1 883  ? 153.672 169.131 184.088 1.00 74.40  ? 1005 TYR A OH  1 
ATOM   6027 N N   . ASP A 1 884  ? 150.042 164.989 182.081 1.00 69.25  ? 1006 ASP A N   1 
ATOM   6028 C CA  . ASP A 1 884  ? 148.896 165.789 182.488 1.00 63.09  ? 1006 ASP A CA  1 
ATOM   6029 C C   . ASP A 1 884  ? 149.440 167.130 182.958 1.00 69.66  ? 1006 ASP A C   1 
ATOM   6030 O O   . ASP A 1 884  ? 150.223 167.178 183.908 1.00 77.71  ? 1006 ASP A O   1 
ATOM   6031 C CB  . ASP A 1 884  ? 148.113 165.085 183.592 1.00 71.08  ? 1006 ASP A CB  1 
ATOM   6032 C CG  . ASP A 1 884  ? 147.050 165.964 184.211 1.00 82.97  ? 1006 ASP A CG  1 
ATOM   6033 O OD1 . ASP A 1 884  ? 146.316 166.640 183.460 1.00 88.07  ? 1006 ASP A OD1 1 
ATOM   6034 O OD2 . ASP A 1 884  ? 146.941 165.967 185.453 1.00 81.79  ? 1006 ASP A OD2 1 
ATOM   6035 N N   . TRP A 1 885  ? 149.039 168.214 182.287 1.00 67.69  ? 1007 TRP A N   1 
ATOM   6036 C CA  . TRP A 1 885  ? 149.614 169.517 182.604 1.00 68.86  ? 1007 TRP A CA  1 
ATOM   6037 C C   . TRP A 1 885  ? 149.006 170.111 183.865 1.00 72.93  ? 1007 TRP A C   1 
ATOM   6038 O O   . TRP A 1 885  ? 149.625 170.957 184.517 1.00 80.37  ? 1007 TRP A O   1 
ATOM   6039 C CB  . TRP A 1 885  ? 149.460 170.480 181.422 1.00 70.19  ? 1007 TRP A CB  1 
ATOM   6040 C CG  . TRP A 1 885  ? 148.046 170.764 180.994 1.00 74.91  ? 1007 TRP A CG  1 
ATOM   6041 C CD1 . TRP A 1 885  ? 147.346 170.107 180.031 1.00 73.66  ? 1007 TRP A CD1 1 
ATOM   6042 C CD2 . TRP A 1 885  ? 147.171 171.787 181.497 1.00 75.88  ? 1007 TRP A CD2 1 
ATOM   6043 N NE1 . TRP A 1 885  ? 146.093 170.644 179.904 1.00 76.75  ? 1007 TRP A NE1 1 
ATOM   6044 C CE2 . TRP A 1 885  ? 145.957 171.675 180.794 1.00 78.23  ? 1007 TRP A CE2 1 
ATOM   6045 C CE3 . TRP A 1 885  ? 147.294 172.781 182.477 1.00 73.46  ? 1007 TRP A CE3 1 
ATOM   6046 C CZ2 . TRP A 1 885  ? 144.874 172.516 181.037 1.00 84.22  ? 1007 TRP A CZ2 1 
ATOM   6047 C CZ3 . TRP A 1 885  ? 146.219 173.615 182.720 1.00 76.84  ? 1007 TRP A CZ3 1 
ATOM   6048 C CH2 . TRP A 1 885  ? 145.024 173.478 182.002 1.00 85.97  ? 1007 TRP A CH2 1 
ATOM   6049 N N   . ARG A 1 886  ? 147.791 169.692 184.217 1.00 69.60  ? 1008 ARG A N   1 
ATOM   6050 C CA  . ARG A 1 886  ? 147.107 170.299 185.352 1.00 69.41  ? 1008 ARG A CA  1 
ATOM   6051 C C   . ARG A 1 886  ? 147.616 169.731 186.670 1.00 75.72  ? 1008 ARG A C   1 
ATOM   6052 O O   . ARG A 1 886  ? 147.939 170.480 187.597 1.00 81.50  ? 1008 ARG A O   1 
ATOM   6053 C CB  . ARG A 1 886  ? 145.599 170.109 185.225 1.00 72.25  ? 1008 ARG A CB  1 
ATOM   6054 C CG  . ARG A 1 886  ? 144.823 171.325 185.670 1.00 77.59  ? 1008 ARG A CG  1 
ATOM   6055 C CD  . ARG A 1 886  ? 143.344 171.171 185.461 1.00 76.84  ? 1008 ARG A CD  1 
ATOM   6056 N NE  . ARG A 1 886  ? 142.584 172.186 186.178 1.00 85.84  ? 1008 ARG A NE  1 
ATOM   6057 C CZ  . ARG A 1 886  ? 141.263 172.286 186.157 1.00 91.61  ? 1008 ARG A CZ  1 
ATOM   6058 N NH1 . ARG A 1 886  ? 140.518 171.448 185.457 1.00 88.31  ? 1008 ARG A NH1 1 
ATOM   6059 N NH2 . ARG A 1 886  ? 140.675 173.252 186.854 1.00 92.11  ? 1008 ARG A NH2 1 
ATOM   6060 N N   . GLY A 1 887  ? 147.697 168.405 186.770 1.00 74.23  ? 1009 GLY A N   1 
ATOM   6061 C CA  . GLY A 1 887  ? 148.252 167.804 187.970 1.00 69.43  ? 1009 GLY A CA  1 
ATOM   6062 C C   . GLY A 1 887  ? 149.765 167.878 188.006 1.00 77.03  ? 1009 GLY A C   1 
ATOM   6063 O O   . GLY A 1 887  ? 150.368 167.898 189.081 1.00 84.04  ? 1009 GLY A O   1 
ATOM   6064 N N   . GLY A 1 888  ? 150.396 167.944 186.838 1.00 73.82  ? 1010 GLY A N   1 
ATOM   6065 C CA  . GLY A 1 888  ? 151.840 167.912 186.756 1.00 70.17  ? 1010 GLY A CA  1 
ATOM   6066 C C   . GLY A 1 888  ? 152.364 166.512 186.968 1.00 73.87  ? 1010 GLY A C   1 
ATOM   6067 O O   . GLY A 1 888  ? 153.276 166.305 187.770 1.00 78.70  ? 1010 GLY A O   1 
ATOM   6068 N N   . ARG A 1 889  ? 151.775 165.537 186.279 1.00 68.98  ? 1011 ARG A N   1 
ATOM   6069 C CA  . ARG A 1 889  ? 152.082 164.129 186.484 1.00 64.10  ? 1011 ARG A CA  1 
ATOM   6070 C C   . ARG A 1 889  ? 152.306 163.430 185.152 1.00 64.41  ? 1011 ARG A C   1 
ATOM   6071 O O   . ARG A 1 889  ? 151.564 163.650 184.192 1.00 69.99  ? 1011 ARG A O   1 
ATOM   6072 C CB  . ARG A 1 889  ? 150.957 163.420 187.246 1.00 63.79  ? 1011 ARG A CB  1 
ATOM   6073 C CG  . ARG A 1 889  ? 150.841 163.793 188.714 1.00 63.36  ? 1011 ARG A CG  1 
ATOM   6074 C CD  . ARG A 1 889  ? 152.120 163.472 189.447 1.00 66.08  ? 1011 ARG A CD  1 
ATOM   6075 N NE  . ARG A 1 889  ? 151.964 163.546 190.892 1.00 78.42  ? 1011 ARG A NE  1 
ATOM   6076 C CZ  . ARG A 1 889  ? 152.229 164.622 191.618 1.00 78.91  ? 1011 ARG A CZ  1 
ATOM   6077 N NH1 . ARG A 1 889  ? 152.646 165.745 191.061 1.00 77.01  ? 1011 ARG A NH1 1 
ATOM   6078 N NH2 . ARG A 1 889  ? 152.079 164.566 192.937 1.00 80.46  ? 1011 ARG A NH2 1 
ATOM   6079 N N   . VAL A 1 890  ? 153.317 162.566 185.111 1.00 63.30  ? 1012 VAL A N   1 
ATOM   6080 C CA  . VAL A 1 890  ? 153.652 161.768 183.937 1.00 56.35  ? 1012 VAL A CA  1 
ATOM   6081 C C   . VAL A 1 890  ? 153.033 160.389 184.117 1.00 62.10  ? 1012 VAL A C   1 
ATOM   6082 O O   . VAL A 1 890  ? 153.244 159.735 185.144 1.00 72.84  ? 1012 VAL A O   1 
ATOM   6083 C CB  . VAL A 1 890  ? 155.180 161.699 183.740 1.00 58.37  ? 1012 VAL A CB  1 
ATOM   6084 C CG1 . VAL A 1 890  ? 155.620 160.516 182.890 1.00 60.39  ? 1012 VAL A CG1 1 
ATOM   6085 C CG2 . VAL A 1 890  ? 155.660 162.945 183.084 1.00 58.02  ? 1012 VAL A CG2 1 
ATOM   6086 N N   . TYR A 1 891  ? 152.242 159.963 183.138 1.00 59.40  ? 1013 TYR A N   1 
ATOM   6087 C CA  . TYR A 1 891  ? 151.556 158.680 183.163 1.00 56.34  ? 1013 TYR A CA  1 
ATOM   6088 C C   . TYR A 1 891  ? 152.168 157.776 182.107 1.00 59.20  ? 1013 TYR A C   1 
ATOM   6089 O O   . TYR A 1 891  ? 152.280 158.173 180.947 1.00 65.64  ? 1013 TYR A O   1 
ATOM   6090 C CB  . TYR A 1 891  ? 150.061 158.843 182.879 1.00 63.00  ? 1013 TYR A CB  1 
ATOM   6091 C CG  . TYR A 1 891  ? 149.258 159.569 183.933 1.00 66.26  ? 1013 TYR A CG  1 
ATOM   6092 C CD1 . TYR A 1 891  ? 149.190 160.967 183.945 1.00 67.84  ? 1013 TYR A CD1 1 
ATOM   6093 C CD2 . TYR A 1 891  ? 148.534 158.854 184.889 1.00 64.64  ? 1013 TYR A CD2 1 
ATOM   6094 C CE1 . TYR A 1 891  ? 148.451 161.637 184.903 1.00 69.56  ? 1013 TYR A CE1 1 
ATOM   6095 C CE2 . TYR A 1 891  ? 147.779 159.516 185.852 1.00 68.89  ? 1013 TYR A CE2 1 
ATOM   6096 C CZ  . TYR A 1 891  ? 147.755 160.905 185.851 1.00 70.81  ? 1013 TYR A CZ  1 
ATOM   6097 O OH  . TYR A 1 891  ? 147.011 161.582 186.787 1.00 78.97  ? 1013 TYR A OH  1 
ATOM   6098 N N   . TRP A 1 892  ? 152.552 156.564 182.498 1.00 58.21  ? 1014 TRP A N   1 
ATOM   6099 C CA  . TRP A 1 892  ? 152.961 155.568 181.521 1.00 51.59  ? 1014 TRP A CA  1 
ATOM   6100 C C   . TRP A 1 892  ? 152.310 154.236 181.844 1.00 54.97  ? 1014 TRP A C   1 
ATOM   6101 O O   . TRP A 1 892  ? 151.895 153.985 182.973 1.00 68.59  ? 1014 TRP A O   1 
ATOM   6102 C CB  . TRP A 1 892  ? 154.497 155.424 181.415 1.00 52.08  ? 1014 TRP A CB  1 
ATOM   6103 C CG  . TRP A 1 892  ? 155.253 154.856 182.587 1.00 52.85  ? 1014 TRP A CG  1 
ATOM   6104 C CD1 . TRP A 1 892  ? 155.405 153.538 182.938 1.00 62.21  ? 1014 TRP A CD1 1 
ATOM   6105 C CD2 . TRP A 1 892  ? 156.038 155.599 183.507 1.00 54.74  ? 1014 TRP A CD2 1 
ATOM   6106 N NE1 . TRP A 1 892  ? 156.189 153.432 184.051 1.00 61.72  ? 1014 TRP A NE1 1 
ATOM   6107 C CE2 . TRP A 1 892  ? 156.601 154.685 184.417 1.00 55.96  ? 1014 TRP A CE2 1 
ATOM   6108 C CE3 . TRP A 1 892  ? 156.305 156.960 183.664 1.00 57.91  ? 1014 TRP A CE3 1 
ATOM   6109 C CZ2 . TRP A 1 892  ? 157.406 155.090 185.473 1.00 57.64  ? 1014 TRP A CZ2 1 
ATOM   6110 C CZ3 . TRP A 1 892  ? 157.113 157.357 184.694 1.00 62.79  ? 1014 TRP A CZ3 1 
ATOM   6111 C CH2 . TRP A 1 892  ? 157.655 156.429 185.593 1.00 61.25  ? 1014 TRP A CH2 1 
ATOM   6112 N N   . THR A 1 893  ? 152.242 153.380 180.832 1.00 54.39  ? 1015 THR A N   1 
ATOM   6113 C CA  . THR A 1 893  ? 151.779 152.009 180.996 1.00 53.39  ? 1015 THR A CA  1 
ATOM   6114 C C   . THR A 1 893  ? 152.977 151.129 181.313 1.00 56.55  ? 1015 THR A C   1 
ATOM   6115 O O   . THR A 1 893  ? 153.870 150.966 180.479 1.00 63.85  ? 1015 THR A O   1 
ATOM   6116 C CB  . THR A 1 893  ? 151.086 151.507 179.737 1.00 56.09  ? 1015 THR A CB  1 
ATOM   6117 O OG1 . THR A 1 893  ? 151.990 151.604 178.633 1.00 67.24  ? 1015 THR A OG1 1 
ATOM   6118 C CG2 . THR A 1 893  ? 149.875 152.319 179.436 1.00 60.34  ? 1015 THR A CG2 1 
ATOM   6119 N N   . ASP A 1 894  ? 152.998 150.560 182.510 1.00 59.27  ? 1016 ASP A N   1 
ATOM   6120 C CA  . ASP A 1 894  ? 153.973 149.531 182.839 1.00 56.91  ? 1016 ASP A CA  1 
ATOM   6121 C C   . ASP A 1 894  ? 153.455 148.214 182.286 1.00 65.35  ? 1016 ASP A C   1 
ATOM   6122 O O   . ASP A 1 894  ? 152.509 147.638 182.828 1.00 72.40  ? 1016 ASP A O   1 
ATOM   6123 C CB  . ASP A 1 894  ? 154.185 149.447 184.345 1.00 62.57  ? 1016 ASP A CB  1 
ATOM   6124 C CG  . ASP A 1 894  ? 155.600 149.063 184.711 1.00 74.18  ? 1016 ASP A CG  1 
ATOM   6125 O OD1 . ASP A 1 894  ? 156.215 148.274 183.968 1.00 71.81  ? 1016 ASP A OD1 1 
ATOM   6126 O OD2 . ASP A 1 894  ? 156.099 149.551 185.745 1.00 84.03  ? 1016 ASP A OD2 1 
ATOM   6127 N N   . LEU A 1 895  ? 154.060 147.743 181.192 1.00 61.81  ? 1017 LEU A N   1 
ATOM   6128 C CA  . LEU A 1 895  ? 153.634 146.485 180.593 1.00 60.83  ? 1017 LEU A CA  1 
ATOM   6129 C C   . LEU A 1 895  ? 154.098 145.278 181.392 1.00 65.07  ? 1017 LEU A C   1 
ATOM   6130 O O   . LEU A 1 895  ? 153.498 144.206 181.274 1.00 72.52  ? 1017 LEU A O   1 
ATOM   6131 C CB  . LEU A 1 895  ? 154.148 146.382 179.161 1.00 59.77  ? 1017 LEU A CB  1 
ATOM   6132 C CG  . LEU A 1 895  ? 153.818 147.528 178.209 1.00 65.88  ? 1017 LEU A CG  1 
ATOM   6133 C CD1 . LEU A 1 895  ? 154.418 147.241 176.853 1.00 69.77  ? 1017 LEU A CD1 1 
ATOM   6134 C CD2 . LEU A 1 895  ? 152.321 147.720 178.098 1.00 62.55  ? 1017 LEU A CD2 1 
ATOM   6135 N N   . ALA A 1 896  ? 155.154 145.424 182.188 1.00 60.94  ? 1018 ALA A N   1 
ATOM   6136 C CA  . ALA A 1 896  ? 155.592 144.336 183.048 1.00 58.51  ? 1018 ALA A CA  1 
ATOM   6137 C C   . ALA A 1 896  ? 154.689 144.167 184.259 1.00 66.57  ? 1018 ALA A C   1 
ATOM   6138 O O   . ALA A 1 896  ? 154.329 143.041 184.614 1.00 76.79  ? 1018 ALA A O   1 
ATOM   6139 C CB  . ALA A 1 896  ? 157.031 144.569 183.490 1.00 59.09  ? 1018 ALA A CB  1 
ATOM   6140 N N   . ARG A 1 897  ? 154.307 145.268 184.899 1.00 65.99  ? 1019 ARG A N   1 
ATOM   6141 C CA  . ARG A 1 897  ? 153.477 145.217 186.093 1.00 58.96  ? 1019 ARG A CA  1 
ATOM   6142 C C   . ARG A 1 897  ? 151.993 145.140 185.787 1.00 62.56  ? 1019 ARG A C   1 
ATOM   6143 O O   . ARG A 1 897  ? 151.217 144.961 186.735 1.00 68.27  ? 1019 ARG A O   1 
ATOM   6144 C CB  . ARG A 1 897  ? 153.730 146.442 186.964 1.00 61.58  ? 1019 ARG A CB  1 
ATOM   6145 C CG  . ARG A 1 897  ? 154.793 146.251 188.003 1.00 70.78  ? 1019 ARG A CG  1 
ATOM   6146 C CD  . ARG A 1 897  ? 154.939 147.488 188.857 1.00 68.76  ? 1019 ARG A CD  1 
ATOM   6147 N NE  . ARG A 1 897  ? 156.173 147.466 189.629 1.00 68.42  ? 1019 ARG A NE  1 
ATOM   6148 C CZ  . ARG A 1 897  ? 157.350 147.875 189.176 1.00 76.20  ? 1019 ARG A CZ  1 
ATOM   6149 N NH1 . ARG A 1 897  ? 157.486 148.388 187.965 1.00 76.85  ? 1019 ARG A NH1 1 
ATOM   6150 N NH2 . ARG A 1 897  ? 158.414 147.779 189.964 1.00 77.28  ? 1019 ARG A NH2 1 
ATOM   6151 N N   . ASN A 1 898  ? 151.622 145.279 184.499 1.00 64.56  ? 1020 ASN A N   1 
ATOM   6152 C CA  . ASN A 1 898  ? 150.247 145.328 183.970 1.00 67.95  ? 1020 ASN A CA  1 
ATOM   6153 C C   . ASN A 1 898  ? 149.413 146.426 184.626 1.00 75.73  ? 1020 ASN A C   1 
ATOM   6154 O O   . ASN A 1 898  ? 148.244 146.230 184.953 1.00 84.16  ? 1020 ASN A O   1 
ATOM   6155 C CB  . ASN A 1 898  ? 149.543 143.971 184.074 1.00 72.94  ? 1020 ASN A CB  1 
ATOM   6156 C CG  . ASN A 1 898  ? 148.735 143.639 182.854 1.00 85.30  ? 1020 ASN A CG  1 
ATOM   6157 O OD1 . ASN A 1 898  ? 148.939 144.209 181.784 1.00 89.45  ? 1020 ASN A OD1 1 
ATOM   6158 N ND2 . ASN A 1 898  ? 147.810 142.703 183.002 1.00 83.68  ? 1020 ASN A ND2 1 
ATOM   6159 N N   . CYS A 1 899  ? 150.023 147.591 184.828 1.00 68.70  ? 1021 CYS A N   1 
ATOM   6160 C CA  . CYS A 1 899  ? 149.350 148.689 185.501 1.00 61.37  ? 1021 CYS A CA  1 
ATOM   6161 C C   . CYS A 1 899  ? 149.843 150.006 184.913 1.00 61.86  ? 1021 CYS A C   1 
ATOM   6162 O O   . CYS A 1 899  ? 150.586 150.029 183.929 1.00 70.07  ? 1021 CYS A O   1 
ATOM   6163 C CB  . CYS A 1 899  ? 149.571 148.609 187.012 1.00 61.93  ? 1021 CYS A CB  1 
ATOM   6164 S SG  . CYS A 1 899  ? 151.200 149.132 187.498 1.00 89.92  ? 1021 CYS A SG  1 
ATOM   6165 N N   . VAL A 1 900  ? 149.421 151.109 185.523 1.00 61.86  ? 1022 VAL A N   1 
ATOM   6166 C CA  . VAL A 1 900  ? 149.719 152.459 185.064 1.00 55.30  ? 1022 VAL A CA  1 
ATOM   6167 C C   . VAL A 1 900  ? 150.455 153.174 186.190 1.00 62.30  ? 1022 VAL A C   1 
ATOM   6168 O O   . VAL A 1 900  ? 150.010 153.142 187.341 1.00 75.53  ? 1022 VAL A O   1 
ATOM   6169 C CB  . VAL A 1 900  ? 148.429 153.197 184.646 1.00 60.43  ? 1022 VAL A CB  1 
ATOM   6170 C CG1 . VAL A 1 900  ? 148.607 154.705 184.551 1.00 64.06  ? 1022 VAL A CG1 1 
ATOM   6171 C CG2 . VAL A 1 900  ? 147.953 152.671 183.313 1.00 64.72  ? 1022 VAL A CG2 1 
ATOM   6172 N N   . VAL A 1 901  ? 151.606 153.764 185.877 1.00 56.22  ? 1023 VAL A N   1 
ATOM   6173 C CA  . VAL A 1 901  ? 152.441 154.433 186.865 1.00 59.56  ? 1023 VAL A CA  1 
ATOM   6174 C C   . VAL A 1 901  ? 152.313 155.939 186.681 1.00 61.95  ? 1023 VAL A C   1 
ATOM   6175 O O   . VAL A 1 901  ? 152.497 156.453 185.572 1.00 64.39  ? 1023 VAL A O   1 
ATOM   6176 C CB  . VAL A 1 901  ? 153.905 153.982 186.745 1.00 59.47  ? 1023 VAL A CB  1 
ATOM   6177 C CG1 . VAL A 1 901  ? 154.676 154.437 187.934 1.00 64.04  ? 1023 VAL A CG1 1 
ATOM   6178 C CG2 . VAL A 1 901  ? 153.984 152.478 186.624 1.00 66.40  ? 1023 VAL A CG2 1 
ATOM   6179 N N   . ARG A 1 902  ? 151.994 156.644 187.765 1.00 66.16  ? 1024 ARG A N   1 
ATOM   6180 C CA  . ARG A 1 902  ? 151.889 158.098 187.786 1.00 62.32  ? 1024 ARG A CA  1 
ATOM   6181 C C   . ARG A 1 902  ? 153.084 158.672 188.535 1.00 67.20  ? 1024 ARG A C   1 
ATOM   6182 O O   . ARG A 1 902  ? 153.328 158.296 189.683 1.00 81.57  ? 1024 ARG A O   1 
ATOM   6183 C CB  . ARG A 1 902  ? 150.585 158.533 188.457 1.00 68.64  ? 1024 ARG A CB  1 
ATOM   6184 C CG  . ARG A 1 902  ? 150.514 160.007 188.791 1.00 70.78  ? 1024 ARG A CG  1 
ATOM   6185 C CD  . ARG A 1 902  ? 149.110 160.435 189.149 1.00 72.27  ? 1024 ARG A CD  1 
ATOM   6186 N NE  . ARG A 1 902  ? 148.736 160.067 190.507 1.00 78.18  ? 1024 ARG A NE  1 
ATOM   6187 C CZ  . ARG A 1 902  ? 147.510 160.179 190.995 1.00 79.48  ? 1024 ARG A CZ  1 
ATOM   6188 N NH1 . ARG A 1 902  ? 146.509 160.619 190.253 1.00 73.28  ? 1024 ARG A NH1 1 
ATOM   6189 N NH2 . ARG A 1 902  ? 147.282 159.836 192.259 1.00 82.83  ? 1024 ARG A NH2 1 
ATOM   6190 N N   . MET A 1 903  ? 153.812 159.594 187.904 1.00 61.64  ? 1025 MET A N   1 
ATOM   6191 C CA  . MET A 1 903  ? 155.109 160.022 188.410 1.00 66.27  ? 1025 MET A CA  1 
ATOM   6192 C C   . MET A 1 903  ? 155.238 161.538 188.361 1.00 70.01  ? 1025 MET A C   1 
ATOM   6193 O O   . MET A 1 903  ? 154.802 162.179 187.402 1.00 74.03  ? 1025 MET A O   1 
ATOM   6194 C CB  . MET A 1 903  ? 156.212 159.313 187.605 1.00 66.34  ? 1025 MET A CB  1 
ATOM   6195 C CG  . MET A 1 903  ? 157.693 159.517 187.956 1.00 71.24  ? 1025 MET A CG  1 
ATOM   6196 S SD  . MET A 1 903  ? 158.558 160.969 187.335 1.00 89.59  ? 1025 MET A SD  1 
ATOM   6197 C CE  . MET A 1 903  ? 158.717 160.562 185.607 1.00 71.22  ? 1025 MET A CE  1 
ATOM   6198 N N   . ASP A 1 904  ? 155.842 162.099 189.405 1.00 69.86  ? 1026 ASP A N   1 
ATOM   6199 C CA  . ASP A 1 904  ? 156.056 163.540 189.512 1.00 72.26  ? 1026 ASP A CA  1 
ATOM   6200 C C   . ASP A 1 904  ? 157.419 163.911 188.943 1.00 77.48  ? 1026 ASP A C   1 
ATOM   6201 O O   . ASP A 1 904  ? 158.435 163.483 189.495 1.00 87.17  ? 1026 ASP A O   1 
ATOM   6202 C CB  . ASP A 1 904  ? 155.976 163.969 190.968 1.00 75.86  ? 1026 ASP A CB  1 
ATOM   6203 C CG  . ASP A 1 904  ? 155.960 165.469 191.136 1.00 86.53  ? 1026 ASP A CG  1 
ATOM   6204 O OD1 . ASP A 1 904  ? 155.226 166.146 190.390 1.00 91.02  ? 1026 ASP A OD1 1 
ATOM   6205 O OD2 . ASP A 1 904  ? 156.684 165.972 192.018 1.00 92.62  ? 1026 ASP A OD2 1 
ATOM   6206 N N   . PRO A 1 905  ? 157.493 164.707 187.864 1.00 73.38  ? 1027 PRO A N   1 
ATOM   6207 C CA  . PRO A 1 905  ? 158.796 164.970 187.222 1.00 78.62  ? 1027 PRO A CA  1 
ATOM   6208 C C   . PRO A 1 905  ? 159.716 165.917 187.974 1.00 87.08  ? 1027 PRO A C   1 
ATOM   6209 O O   . PRO A 1 905  ? 160.918 165.940 187.674 1.00 91.24  ? 1027 PRO A O   1 
ATOM   6210 C CB  . PRO A 1 905  ? 158.404 165.582 185.868 1.00 76.55  ? 1027 PRO A CB  1 
ATOM   6211 C CG  . PRO A 1 905  ? 156.964 165.311 185.711 1.00 73.99  ? 1027 PRO A CG  1 
ATOM   6212 C CD  . PRO A 1 905  ? 156.388 165.255 187.068 1.00 70.66  ? 1027 PRO A CD  1 
ATOM   6213 N N   . TRP A 1 906  ? 159.208 166.696 188.926 1.00 87.43  ? 1028 TRP A N   1 
ATOM   6214 C CA  . TRP A 1 906  ? 160.087 167.540 189.725 1.00 88.45  ? 1028 TRP A CA  1 
ATOM   6215 C C   . TRP A 1 906  ? 160.819 166.733 190.786 1.00 90.61  ? 1028 TRP A C   1 
ATOM   6216 O O   . TRP A 1 906  ? 161.922 167.104 191.201 1.00 100.25 ? 1028 TRP A O   1 
ATOM   6217 C CB  . TRP A 1 906  ? 159.295 168.668 190.387 1.00 89.06  ? 1028 TRP A CB  1 
ATOM   6218 C CG  . TRP A 1 906  ? 158.781 169.717 189.454 1.00 95.17  ? 1028 TRP A CG  1 
ATOM   6219 C CD1 . TRP A 1 906  ? 159.055 169.847 188.124 1.00 97.80  ? 1028 TRP A CD1 1 
ATOM   6220 C CD2 . TRP A 1 906  ? 157.902 170.793 189.790 1.00 102.34 ? 1028 TRP A CD2 1 
ATOM   6221 N NE1 . TRP A 1 906  ? 158.396 170.934 187.608 1.00 102.12 ? 1028 TRP A NE1 1 
ATOM   6222 C CE2 . TRP A 1 906  ? 157.683 171.535 188.611 1.00 107.42 ? 1028 TRP A CE2 1 
ATOM   6223 C CE3 . TRP A 1 906  ? 157.278 171.203 190.974 1.00 99.91  ? 1028 TRP A CE3 1 
ATOM   6224 C CZ2 . TRP A 1 906  ? 156.863 172.665 188.581 1.00 107.27 ? 1028 TRP A CZ2 1 
ATOM   6225 C CZ3 . TRP A 1 906  ? 156.463 172.326 190.945 1.00 104.21 ? 1028 TRP A CZ3 1 
ATOM   6226 C CH2 . TRP A 1 906  ? 156.264 173.044 189.755 1.00 107.23 ? 1028 TRP A CH2 1 
ATOM   6227 N N   . SER A 1 907  ? 160.222 165.633 191.240 1.00 84.17  ? 1029 SER A N   1 
ATOM   6228 C CA  . SER A 1 907  ? 160.757 164.857 192.353 1.00 87.52  ? 1029 SER A CA  1 
ATOM   6229 C C   . SER A 1 907  ? 161.202 163.463 191.928 1.00 86.34  ? 1029 SER A C   1 
ATOM   6230 O O   . SER A 1 907  ? 162.312 163.036 192.255 1.00 91.62  ? 1029 SER A O   1 
ATOM   6231 C CB  . SER A 1 907  ? 159.715 164.762 193.472 1.00 88.35  ? 1029 SER A CB  1 
ATOM   6232 O OG  . SER A 1 907  ? 160.169 163.916 194.511 1.00 90.94  ? 1029 SER A OG  1 
ATOM   6233 N N   . GLY A 1 908  ? 160.354 162.741 191.205 1.00 81.02  ? 1030 GLY A N   1 
ATOM   6234 C CA  . GLY A 1 908  ? 160.625 161.363 190.863 1.00 71.50  ? 1030 GLY A CA  1 
ATOM   6235 C C   . GLY A 1 908  ? 159.871 160.347 191.682 1.00 76.25  ? 1030 GLY A C   1 
ATOM   6236 O O   . GLY A 1 908  ? 160.245 159.172 191.669 1.00 82.78  ? 1030 GLY A O   1 
ATOM   6237 N N   . SER A 1 909  ? 158.848 160.761 192.420 1.00 75.00  ? 1031 SER A N   1 
ATOM   6238 C CA  . SER A 1 909  ? 158.054 159.830 193.204 1.00 71.57  ? 1031 SER A CA  1 
ATOM   6239 C C   . SER A 1 909  ? 156.979 159.214 192.321 1.00 71.37  ? 1031 SER A C   1 
ATOM   6240 O O   . SER A 1 909  ? 156.272 159.928 191.605 1.00 76.19  ? 1031 SER A O   1 
ATOM   6241 C CB  . SER A 1 909  ? 157.436 160.547 194.401 1.00 74.36  ? 1031 SER A CB  1 
ATOM   6242 O OG  . SER A 1 909  ? 156.674 161.668 193.991 1.00 83.61  ? 1031 SER A OG  1 
ATOM   6243 N N   . ARG A 1 910  ? 156.863 157.890 192.359 1.00 65.04  ? 1032 ARG A N   1 
ATOM   6244 C CA  . ARG A 1 910  ? 155.971 157.165 191.466 1.00 59.95  ? 1032 ARG A CA  1 
ATOM   6245 C C   . ARG A 1 910  ? 154.756 156.663 192.234 1.00 63.95  ? 1032 ARG A C   1 
ATOM   6246 O O   . ARG A 1 910  ? 154.841 156.363 193.422 1.00 74.77  ? 1032 ARG A O   1 
ATOM   6247 C CB  . ARG A 1 910  ? 156.636 155.944 190.832 1.00 60.74  ? 1032 ARG A CB  1 
ATOM   6248 C CG  . ARG A 1 910  ? 157.597 156.060 189.654 1.00 66.58  ? 1032 ARG A CG  1 
ATOM   6249 C CD  . ARG A 1 910  ? 158.957 156.560 190.030 1.00 75.45  ? 1032 ARG A CD  1 
ATOM   6250 N NE  . ARG A 1 910  ? 159.863 156.590 188.893 1.00 80.78  ? 1032 ARG A NE  1 
ATOM   6251 C CZ  . ARG A 1 910  ? 160.606 155.560 188.516 1.00 74.40  ? 1032 ARG A CZ  1 
ATOM   6252 N NH1 . ARG A 1 910  ? 160.563 154.405 189.151 1.00 64.11  ? 1032 ARG A NH1 1 
ATOM   6253 N NH2 . ARG A 1 910  ? 161.415 155.690 187.477 1.00 80.97  ? 1032 ARG A NH2 1 
ATOM   6254 N N   . GLU A 1 911  ? 153.647 156.475 191.522 1.00 62.74  ? 1033 GLU A N   1 
ATOM   6255 C CA  . GLU A 1 911  ? 152.415 156.004 192.139 1.00 62.18  ? 1033 GLU A CA  1 
ATOM   6256 C C   . GLU A 1 911  ? 151.756 154.977 191.234 1.00 68.48  ? 1033 GLU A C   1 
ATOM   6257 O O   . GLU A 1 911  ? 151.525 155.250 190.053 1.00 69.18  ? 1033 GLU A O   1 
ATOM   6258 C CB  . GLU A 1 911  ? 151.455 157.170 192.404 1.00 72.12  ? 1033 GLU A CB  1 
ATOM   6259 C CG  . GLU A 1 911  ? 150.346 156.860 193.394 1.00 84.61  ? 1033 GLU A CG  1 
ATOM   6260 C CD  . GLU A 1 911  ? 149.676 158.110 193.930 1.00 97.66  ? 1033 GLU A CD  1 
ATOM   6261 O OE1 . GLU A 1 911  ? 149.936 159.204 193.387 1.00 97.79  ? 1033 GLU A OE1 1 
ATOM   6262 O OE2 . GLU A 1 911  ? 148.893 158.003 194.898 1.00 92.21  ? 1033 GLU A OE2 1 
ATOM   6263 N N   . LEU A 1 912  ? 151.454 153.806 191.787 1.00 67.93  ? 1034 LEU A N   1 
ATOM   6264 C CA  . LEU A 1 912  ? 150.823 152.738 191.021 1.00 64.17  ? 1034 LEU A CA  1 
ATOM   6265 C C   . LEU A 1 912  ? 149.318 152.953 190.979 1.00 66.45  ? 1034 LEU A C   1 
ATOM   6266 O O   . LEU A 1 912  ? 148.685 153.168 192.015 1.00 74.80  ? 1034 LEU A O   1 
ATOM   6267 C CB  . LEU A 1 912  ? 151.139 151.380 191.641 1.00 64.04  ? 1034 LEU A CB  1 
ATOM   6268 C CG  . LEU A 1 912  ? 152.592 150.915 191.598 1.00 62.65  ? 1034 LEU A CG  1 
ATOM   6269 C CD1 . LEU A 1 912  ? 152.740 149.552 192.238 1.00 58.10  ? 1034 LEU A CD1 1 
ATOM   6270 C CD2 . LEU A 1 912  ? 153.086 150.889 190.179 1.00 64.05  ? 1034 LEU A CD2 1 
ATOM   6271 N N   . LEU A 1 913  ? 148.747 152.887 189.780 1.00 59.28  ? 1035 LEU A N   1 
ATOM   6272 C CA  . LEU A 1 913  ? 147.333 153.155 189.607 1.00 62.89  ? 1035 LEU A CA  1 
ATOM   6273 C C   . LEU A 1 913  ? 146.611 151.888 189.165 1.00 65.98  ? 1035 LEU A C   1 
ATOM   6274 O O   . LEU A 1 913  ? 147.168 151.108 188.386 1.00 66.63  ? 1035 LEU A O   1 
ATOM   6275 C CB  . LEU A 1 913  ? 147.113 154.269 188.570 1.00 63.37  ? 1035 LEU A CB  1 
ATOM   6276 C CG  . LEU A 1 913  ? 146.792 155.678 189.065 1.00 69.27  ? 1035 LEU A CG  1 
ATOM   6277 C CD1 . LEU A 1 913  ? 147.894 156.235 189.941 1.00 67.27  ? 1035 LEU A CD1 1 
ATOM   6278 C CD2 . LEU A 1 913  ? 146.563 156.590 187.877 1.00 71.61  ? 1035 LEU A CD2 1 
ATOM   6279 N N   . PRO A 1 914  ? 145.369 151.646 189.632 1.00 63.86  ? 1036 PRO A N   1 
ATOM   6280 C CA  . PRO A 1 914  ? 144.670 150.397 189.253 1.00 58.81  ? 1036 PRO A CA  1 
ATOM   6281 C C   . PRO A 1 914  ? 143.954 150.462 187.907 1.00 66.38  ? 1036 PRO A C   1 
ATOM   6282 O O   . PRO A 1 914  ? 142.730 150.371 187.796 1.00 69.26  ? 1036 PRO A O   1 
ATOM   6283 C CB  . PRO A 1 914  ? 143.699 150.204 190.420 1.00 56.70  ? 1036 PRO A CB  1 
ATOM   6284 C CG  . PRO A 1 914  ? 143.407 151.563 190.891 1.00 59.48  ? 1036 PRO A CG  1 
ATOM   6285 C CD  . PRO A 1 914  ? 144.644 152.376 190.689 1.00 62.61  ? 1036 PRO A CD  1 
ATOM   6286 N N   . VAL A 1 915  ? 144.738 150.606 186.843 1.00 64.51  ? 1037 VAL A N   1 
ATOM   6287 C CA  . VAL A 1 915  ? 144.257 150.557 185.468 1.00 64.59  ? 1037 VAL A CA  1 
ATOM   6288 C C   . VAL A 1 915  ? 144.998 149.409 184.800 1.00 70.77  ? 1037 VAL A C   1 
ATOM   6289 O O   . VAL A 1 915  ? 146.215 149.483 184.606 1.00 77.37  ? 1037 VAL A O   1 
ATOM   6290 C CB  . VAL A 1 915  ? 144.500 151.877 184.726 1.00 58.23  ? 1037 VAL A CB  1 
ATOM   6291 C CG1 . VAL A 1 915  ? 144.106 151.749 183.284 1.00 63.31  ? 1037 VAL A CG1 1 
ATOM   6292 C CG2 . VAL A 1 915  ? 143.739 153.011 185.374 1.00 66.91  ? 1037 VAL A CG2 1 
ATOM   6293 N N   . PHE A 1 916  ? 144.277 148.356 184.436 1.00 70.02  ? 1038 PHE A N   1 
ATOM   6294 C CA  . PHE A 1 916  ? 144.904 147.095 184.077 1.00 65.27  ? 1038 PHE A CA  1 
ATOM   6295 C C   . PHE A 1 916  ? 144.823 146.846 182.580 1.00 73.14  ? 1038 PHE A C   1 
ATOM   6296 O O   . PHE A 1 916  ? 143.867 147.261 181.917 1.00 80.66  ? 1038 PHE A O   1 
ATOM   6297 C CB  . PHE A 1 916  ? 144.255 145.938 184.828 1.00 73.23  ? 1038 PHE A CB  1 
ATOM   6298 C CG  . PHE A 1 916  ? 144.263 146.114 186.309 1.00 72.10  ? 1038 PHE A CG  1 
ATOM   6299 C CD1 . PHE A 1 916  ? 145.434 145.917 187.038 1.00 67.11  ? 1038 PHE A CD1 1 
ATOM   6300 C CD2 . PHE A 1 916  ? 143.097 146.491 186.974 1.00 70.83  ? 1038 PHE A CD2 1 
ATOM   6301 C CE1 . PHE A 1 916  ? 145.443 146.088 188.418 1.00 64.01  ? 1038 PHE A CE1 1 
ATOM   6302 C CE2 . PHE A 1 916  ? 143.092 146.666 188.349 1.00 68.89  ? 1038 PHE A CE2 1 
ATOM   6303 C CZ  . PHE A 1 916  ? 144.266 146.460 189.069 1.00 65.46  ? 1038 PHE A CZ  1 
ATOM   6304 N N   . GLU A 1 917  ? 145.869 146.175 182.071 1.00 72.31  ? 1039 GLU A N   1 
ATOM   6305 C CA  . GLU A 1 917  ? 146.103 145.778 180.676 1.00 73.99  ? 1039 GLU A CA  1 
ATOM   6306 C C   . GLU A 1 917  ? 146.108 146.948 179.695 1.00 77.09  ? 1039 GLU A C   1 
ATOM   6307 O O   . GLU A 1 917  ? 145.792 146.767 178.519 1.00 83.68  ? 1039 GLU A O   1 
ATOM   6308 C CB  . GLU A 1 917  ? 145.104 144.711 180.196 1.00 77.74  ? 1039 GLU A CB  1 
ATOM   6309 C CG  . GLU A 1 917  ? 145.143 143.395 180.943 1.00 85.93  ? 1039 GLU A CG  1 
ATOM   6310 C CD  . GLU A 1 917  ? 144.129 143.324 182.065 1.00 96.22  ? 1039 GLU A CD  1 
ATOM   6311 O OE1 . GLU A 1 917  ? 142.972 143.744 181.850 1.00 94.60  ? 1039 GLU A OE1 1 
ATOM   6312 O OE2 . GLU A 1 917  ? 144.483 142.837 183.159 1.00 95.26  ? 1039 GLU A OE2 1 
ATOM   6313 N N   . ALA A 1 918  ? 146.499 148.140 180.131 1.00 71.47  ? 1040 ALA A N   1 
ATOM   6314 C CA  . ALA A 1 918  ? 146.491 149.295 179.250 1.00 61.08  ? 1040 ALA A CA  1 
ATOM   6315 C C   . ALA A 1 918  ? 147.758 149.322 178.414 1.00 67.22  ? 1040 ALA A C   1 
ATOM   6316 O O   . ALA A 1 918  ? 148.855 149.063 178.913 1.00 82.74  ? 1040 ALA A O   1 
ATOM   6317 C CB  . ALA A 1 918  ? 146.368 150.584 180.059 1.00 64.98  ? 1040 ALA A CB  1 
ATOM   6318 N N   . ASN A 1 919  ? 147.600 149.614 177.127 1.00 64.60  ? 1041 ASN A N   1 
ATOM   6319 C CA  . ASN A 1 919  ? 148.733 149.858 176.247 1.00 62.83  ? 1041 ASN A CA  1 
ATOM   6320 C C   . ASN A 1 919  ? 148.966 151.337 175.999 1.00 64.05  ? 1041 ASN A C   1 
ATOM   6321 O O   . ASN A 1 919  ? 150.111 151.793 176.033 1.00 71.57  ? 1041 ASN A O   1 
ATOM   6322 C CB  . ASN A 1 919  ? 148.538 149.150 174.904 1.00 63.95  ? 1041 ASN A CB  1 
ATOM   6323 C CG  . ASN A 1 919  ? 148.491 147.648 175.040 1.00 78.45  ? 1041 ASN A CG  1 
ATOM   6324 O OD1 . ASN A 1 919  ? 147.465 147.023 174.779 1.00 91.62  ? 1041 ASN A OD1 1 
ATOM   6325 N ND2 . ASN A 1 919  ? 149.606 147.054 175.438 1.00 80.28  ? 1041 ASN A ND2 1 
ATOM   6326 N N   . PHE A 1 920  ? 147.904 152.095 175.750 1.00 60.88  ? 1042 PHE A N   1 
ATOM   6327 C CA  . PHE A 1 920  ? 147.998 153.515 175.458 1.00 62.80  ? 1042 PHE A CA  1 
ATOM   6328 C C   . PHE A 1 920  ? 147.091 154.279 176.405 1.00 66.55  ? 1042 PHE A C   1 
ATOM   6329 O O   . PHE A 1 920  ? 146.062 153.769 176.845 1.00 72.99  ? 1042 PHE A O   1 
ATOM   6330 C CB  . PHE A 1 920  ? 147.623 153.805 174.000 1.00 64.55  ? 1042 PHE A CB  1 
ATOM   6331 C CG  . PHE A 1 920  ? 148.193 152.816 173.036 1.00 72.17  ? 1042 PHE A CG  1 
ATOM   6332 C CD1 . PHE A 1 920  ? 149.572 152.764 172.826 1.00 76.87  ? 1042 PHE A CD1 1 
ATOM   6333 C CD2 . PHE A 1 920  ? 147.365 151.914 172.371 1.00 71.16  ? 1042 PHE A CD2 1 
ATOM   6334 C CE1 . PHE A 1 920  ? 150.122 151.840 171.949 1.00 74.58  ? 1042 PHE A CE1 1 
ATOM   6335 C CE2 . PHE A 1 920  ? 147.902 150.981 171.491 1.00 70.46  ? 1042 PHE A CE2 1 
ATOM   6336 C CZ  . PHE A 1 920  ? 149.288 150.946 171.288 1.00 75.08  ? 1042 PHE A CZ  1 
ATOM   6337 N N   . LEU A 1 921  ? 147.490 155.505 176.727 1.00 66.18  ? 1043 LEU A N   1 
ATOM   6338 C CA  . LEU A 1 921  ? 146.758 156.337 177.666 1.00 59.16  ? 1043 LEU A CA  1 
ATOM   6339 C C   . LEU A 1 921  ? 146.459 157.692 177.052 1.00 59.80  ? 1043 LEU A C   1 
ATOM   6340 O O   . LEU A 1 921  ? 147.054 158.087 176.046 1.00 73.50  ? 1043 LEU A O   1 
ATOM   6341 C CB  . LEU A 1 921  ? 147.529 156.565 178.964 1.00 63.98  ? 1043 LEU A CB  1 
ATOM   6342 C CG  . LEU A 1 921  ? 147.739 155.401 179.919 1.00 68.84  ? 1043 LEU A CG  1 
ATOM   6343 C CD1 . LEU A 1 921  ? 148.851 155.746 180.876 1.00 61.48  ? 1043 LEU A CD1 1 
ATOM   6344 C CD2 . LEU A 1 921  ? 146.470 155.065 180.665 1.00 71.49  ? 1043 LEU A CD2 1 
ATOM   6345 N N   . ALA A 1 922  ? 145.501 158.376 177.678 1.00 53.13  ? 1044 ALA A N   1 
ATOM   6346 C CA  . ALA A 1 922  ? 145.252 159.803 177.540 1.00 57.49  ? 1044 ALA A CA  1 
ATOM   6347 C C   . ALA A 1 922  ? 144.486 160.237 178.775 1.00 61.08  ? 1044 ALA A C   1 
ATOM   6348 O O   . ALA A 1 922  ? 143.804 159.423 179.396 1.00 73.50  ? 1044 ALA A O   1 
ATOM   6349 C CB  . ALA A 1 922  ? 144.441 160.154 176.290 1.00 63.52  ? 1044 ALA A CB  1 
ATOM   6350 N N   . LEU A 1 923  ? 144.585 161.512 179.130 1.00 60.82  ? 1045 LEU A N   1 
ATOM   6351 C CA  . LEU A 1 923  ? 143.823 162.029 180.255 1.00 67.83  ? 1045 LEU A CA  1 
ATOM   6352 C C   . LEU A 1 923  ? 143.179 163.350 179.869 1.00 73.81  ? 1045 LEU A C   1 
ATOM   6353 O O   . LEU A 1 923  ? 143.832 164.222 179.289 1.00 77.78  ? 1045 LEU A O   1 
ATOM   6354 C CB  . LEU A 1 923  ? 144.704 162.149 181.513 1.00 59.97  ? 1045 LEU A CB  1 
ATOM   6355 C CG  . LEU A 1 923  ? 144.102 162.508 182.881 1.00 74.36  ? 1045 LEU A CG  1 
ATOM   6356 C CD1 . LEU A 1 923  ? 144.898 161.811 183.912 1.00 71.08  ? 1045 LEU A CD1 1 
ATOM   6357 C CD2 . LEU A 1 923  ? 144.191 163.987 183.223 1.00 75.60  ? 1045 LEU A CD2 1 
ATOM   6358 N N   . ASP A 1 924  ? 141.906 163.479 180.204 1.00 72.12  ? 1046 ASP A N   1 
ATOM   6359 C CA  . ASP A 1 924  ? 141.151 164.705 180.007 1.00 72.69  ? 1046 ASP A CA  1 
ATOM   6360 C C   . ASP A 1 924  ? 141.482 165.680 181.127 1.00 73.12  ? 1046 ASP A C   1 
ATOM   6361 O O   . ASP A 1 924  ? 141.245 165.357 182.294 1.00 78.17  ? 1046 ASP A O   1 
ATOM   6362 C CB  . ASP A 1 924  ? 139.662 164.389 180.006 1.00 76.23  ? 1046 ASP A CB  1 
ATOM   6363 C CG  . ASP A 1 924  ? 138.855 165.352 179.166 1.00 89.24  ? 1046 ASP A CG  1 
ATOM   6364 O OD1 . ASP A 1 924  ? 139.378 166.422 178.809 1.00 93.24  ? 1046 ASP A OD1 1 
ATOM   6365 O OD2 . ASP A 1 924  ? 137.680 165.045 178.881 1.00 93.65  ? 1046 ASP A OD2 1 
ATOM   6366 N N   . PRO A 1 925  ? 142.020 166.872 180.832 1.00 78.24  ? 1047 PRO A N   1 
ATOM   6367 C CA  . PRO A 1 925  ? 142.421 167.781 181.915 1.00 74.34  ? 1047 PRO A CA  1 
ATOM   6368 C C   . PRO A 1 925  ? 141.271 168.520 182.579 1.00 83.00  ? 1047 PRO A C   1 
ATOM   6369 O O   . PRO A 1 925  ? 141.472 169.093 183.650 1.00 87.90  ? 1047 PRO A O   1 
ATOM   6370 C CB  . PRO A 1 925  ? 143.365 168.763 181.209 1.00 73.82  ? 1047 PRO A CB  1 
ATOM   6371 C CG  . PRO A 1 925  ? 143.737 168.108 179.930 1.00 78.58  ? 1047 PRO A CG  1 
ATOM   6372 C CD  . PRO A 1 925  ? 142.535 167.339 179.535 1.00 84.35  ? 1047 PRO A CD  1 
ATOM   6373 N N   . ARG A 1 926  ? 140.080 168.535 181.973 1.00 80.44  ? 1048 ARG A N   1 
ATOM   6374 C CA  . ARG A 1 926  ? 138.981 169.311 182.541 1.00 79.38  ? 1048 ARG A CA  1 
ATOM   6375 C C   . ARG A 1 926  ? 138.349 168.631 183.748 1.00 86.54  ? 1048 ARG A C   1 
ATOM   6376 O O   . ARG A 1 926  ? 137.902 169.314 184.677 1.00 88.37  ? 1048 ARG A O   1 
ATOM   6377 C CB  . ARG A 1 926  ? 137.912 169.578 181.487 1.00 84.51  ? 1048 ARG A CB  1 
ATOM   6378 C CG  . ARG A 1 926  ? 138.395 170.279 180.249 1.00 93.61  ? 1048 ARG A CG  1 
ATOM   6379 C CD  . ARG A 1 926  ? 137.371 170.124 179.156 1.00 95.46  ? 1048 ARG A CD  1 
ATOM   6380 N NE  . ARG A 1 926  ? 137.015 168.725 178.964 1.00 96.68  ? 1048 ARG A NE  1 
ATOM   6381 C CZ  . ARG A 1 926  ? 136.165 168.293 178.045 1.00 97.34  ? 1048 ARG A CZ  1 
ATOM   6382 N NH1 . ARG A 1 926  ? 135.542 169.132 177.236 1.00 97.90  ? 1048 ARG A NH1 1 
ATOM   6383 N NH2 . ARG A 1 926  ? 135.939 166.990 177.931 1.00 93.57  ? 1048 ARG A NH2 1 
ATOM   6384 N N   . GLN A 1 927  ? 138.318 167.301 183.773 1.00 90.35  ? 1049 GLN A N   1 
ATOM   6385 C CA  . GLN A 1 927  ? 137.663 166.581 184.853 1.00 82.36  ? 1049 GLN A CA  1 
ATOM   6386 C C   . GLN A 1 927  ? 138.522 165.477 185.444 1.00 83.04  ? 1049 GLN A C   1 
ATOM   6387 O O   . GLN A 1 927  ? 138.169 164.940 186.499 1.00 92.13  ? 1049 GLN A O   1 
ATOM   6388 C CB  . GLN A 1 927  ? 136.334 165.977 184.377 1.00 74.18  ? 1049 GLN A CB  1 
ATOM   6389 C CG  . GLN A 1 927  ? 136.453 164.828 183.394 1.00 80.16  ? 1049 GLN A CG  1 
ATOM   6390 C CD  . GLN A 1 927  ? 136.590 165.223 181.932 1.00 90.42  ? 1049 GLN A CD  1 
ATOM   6391 O OE1 . GLN A 1 927  ? 136.900 166.362 181.587 1.00 94.49  ? 1049 GLN A OE1 1 
ATOM   6392 N NE2 . GLN A 1 927  ? 136.330 164.265 181.057 1.00 89.38  ? 1049 GLN A NE2 1 
ATOM   6393 N N   . GLY A 1 928  ? 139.636 165.130 184.810 1.00 78.37  ? 1050 GLY A N   1 
ATOM   6394 C CA  . GLY A 1 928  ? 140.563 164.181 185.381 1.00 70.58  ? 1050 GLY A CA  1 
ATOM   6395 C C   . GLY A 1 928  ? 140.339 162.728 185.033 1.00 77.41  ? 1050 GLY A C   1 
ATOM   6396 O O   . GLY A 1 928  ? 140.912 161.866 185.705 1.00 84.66  ? 1050 GLY A O   1 
ATOM   6397 N N   . HIS A 1 929  ? 139.530 162.418 184.021 1.00 79.22  ? 1051 HIS A N   1 
ATOM   6398 C CA  . HIS A 1 929  ? 139.310 161.027 183.642 1.00 77.93  ? 1051 HIS A CA  1 
ATOM   6399 C C   . HIS A 1 929  ? 140.495 160.493 182.853 1.00 72.37  ? 1051 HIS A C   1 
ATOM   6400 O O   . HIS A 1 929  ? 141.002 161.160 181.949 1.00 75.74  ? 1051 HIS A O   1 
ATOM   6401 C CB  . HIS A 1 929  ? 138.034 160.858 182.819 1.00 83.69  ? 1051 HIS A CB  1 
ATOM   6402 C CG  . HIS A 1 929  ? 136.779 160.952 183.625 1.00 89.05  ? 1051 HIS A CG  1 
ATOM   6403 N ND1 . HIS A 1 929  ? 135.628 161.538 183.148 1.00 86.50  ? 1051 HIS A ND1 1 
ATOM   6404 C CD2 . HIS A 1 929  ? 136.504 160.560 184.889 1.00 94.54  ? 1051 HIS A CD2 1 
ATOM   6405 C CE1 . HIS A 1 929  ? 134.695 161.496 184.080 1.00 94.23  ? 1051 HIS A CE1 1 
ATOM   6406 N NE2 . HIS A 1 929  ? 135.200 160.904 185.147 1.00 100.11 ? 1051 HIS A NE2 1 
ATOM   6407 N N   . LEU A 1 930  ? 140.929 159.285 183.197 1.00 68.51  ? 1052 LEU A N   1 
ATOM   6408 C CA  . LEU A 1 930  ? 142.017 158.624 182.493 1.00 66.21  ? 1052 LEU A CA  1 
ATOM   6409 C C   . LEU A 1 930  ? 141.423 157.692 181.447 1.00 66.35  ? 1052 LEU A C   1 
ATOM   6410 O O   . LEU A 1 930  ? 140.713 156.742 181.786 1.00 73.78  ? 1052 LEU A O   1 
ATOM   6411 C CB  . LEU A 1 930  ? 142.903 157.853 183.470 1.00 66.75  ? 1052 LEU A CB  1 
ATOM   6412 C CG  . LEU A 1 930  ? 144.148 157.184 182.892 1.00 67.25  ? 1052 LEU A CG  1 
ATOM   6413 C CD1 . LEU A 1 930  ? 145.081 158.225 182.313 1.00 65.60  ? 1052 LEU A CD1 1 
ATOM   6414 C CD2 . LEU A 1 930  ? 144.855 156.380 183.955 1.00 73.41  ? 1052 LEU A CD2 1 
ATOM   6415 N N   . TYR A 1 931  ? 141.698 157.976 180.182 1.00 62.94  ? 1053 TYR A N   1 
ATOM   6416 C CA  . TYR A 1 931  ? 141.226 157.167 179.069 1.00 59.43  ? 1053 TYR A CA  1 
ATOM   6417 C C   . TYR A 1 931  ? 142.331 156.206 178.674 1.00 62.77  ? 1053 TYR A C   1 
ATOM   6418 O O   . TYR A 1 931  ? 143.476 156.620 178.488 1.00 73.25  ? 1053 TYR A O   1 
ATOM   6419 C CB  . TYR A 1 931  ? 140.835 158.042 177.880 1.00 62.95  ? 1053 TYR A CB  1 
ATOM   6420 C CG  . TYR A 1 931  ? 139.572 158.837 178.087 1.00 70.50  ? 1053 TYR A CG  1 
ATOM   6421 C CD1 . TYR A 1 931  ? 139.609 160.098 178.697 1.00 72.97  ? 1053 TYR A CD1 1 
ATOM   6422 C CD2 . TYR A 1 931  ? 138.342 158.333 177.664 1.00 67.87  ? 1053 TYR A CD2 1 
ATOM   6423 C CE1 . TYR A 1 931  ? 138.447 160.832 178.890 1.00 77.38  ? 1053 TYR A CE1 1 
ATOM   6424 C CE2 . TYR A 1 931  ? 137.175 159.057 177.849 1.00 70.86  ? 1053 TYR A CE2 1 
ATOM   6425 C CZ  . TYR A 1 931  ? 137.240 160.305 178.461 1.00 76.66  ? 1053 TYR A CZ  1 
ATOM   6426 O OH  . TYR A 1 931  ? 136.091 161.033 178.653 1.00 86.68  ? 1053 TYR A OH  1 
ATOM   6427 N N   . TYR A 1 932  ? 141.996 154.931 178.553 1.00 63.98  ? 1054 TYR A N   1 
ATOM   6428 C CA  . TYR A 1 932  ? 143.015 153.920 178.329 1.00 63.57  ? 1054 TYR A CA  1 
ATOM   6429 C C   . TYR A 1 932  ? 142.572 152.959 177.244 1.00 67.43  ? 1054 TYR A C   1 
ATOM   6430 O O   . TYR A 1 932  ? 141.376 152.777 177.012 1.00 76.59  ? 1054 TYR A O   1 
ATOM   6431 C CB  . TYR A 1 932  ? 143.356 153.155 179.617 1.00 62.61  ? 1054 TYR A CB  1 
ATOM   6432 C CG  . TYR A 1 932  ? 142.238 152.376 180.285 1.00 63.23  ? 1054 TYR A CG  1 
ATOM   6433 C CD1 . TYR A 1 932  ? 141.354 153.007 181.172 1.00 62.83  ? 1054 TYR A CD1 1 
ATOM   6434 C CD2 . TYR A 1 932  ? 142.115 150.996 180.091 1.00 63.87  ? 1054 TYR A CD2 1 
ATOM   6435 C CE1 . TYR A 1 932  ? 140.349 152.293 181.810 1.00 66.80  ? 1054 TYR A CE1 1 
ATOM   6436 C CE2 . TYR A 1 932  ? 141.111 150.271 180.723 1.00 66.38  ? 1054 TYR A CE2 1 
ATOM   6437 C CZ  . TYR A 1 932  ? 140.240 150.930 181.579 1.00 69.24  ? 1054 TYR A CZ  1 
ATOM   6438 O OH  . TYR A 1 932  ? 139.244 150.222 182.207 1.00 78.74  ? 1054 TYR A OH  1 
ATOM   6439 N N   . ALA A 1 933  ? 143.548 152.356 176.577 1.00 68.12  ? 1055 ALA A N   1 
ATOM   6440 C CA  . ALA A 1 933  ? 143.294 151.401 175.511 1.00 66.01  ? 1055 ALA A CA  1 
ATOM   6441 C C   . ALA A 1 933  ? 143.980 150.087 175.842 1.00 70.77  ? 1055 ALA A C   1 
ATOM   6442 O O   . ALA A 1 933  ? 145.194 150.050 176.061 1.00 77.91  ? 1055 ALA A O   1 
ATOM   6443 C CB  . ALA A 1 933  ? 143.779 151.930 174.163 1.00 68.80  ? 1055 ALA A CB  1 
ATOM   6444 N N   . THR A 1 934  ? 143.197 149.021 175.863 1.00 70.86  ? 1056 THR A N   1 
ATOM   6445 C CA  . THR A 1 934  ? 143.656 147.644 175.900 1.00 70.32  ? 1056 THR A CA  1 
ATOM   6446 C C   . THR A 1 934  ? 143.846 147.248 174.426 1.00 79.81  ? 1056 THR A C   1 
ATOM   6447 O O   . THR A 1 934  ? 143.458 147.997 173.526 1.00 88.64  ? 1056 THR A O   1 
ATOM   6448 C CB  . THR A 1 934  ? 142.616 146.850 176.715 1.00 76.52  ? 1056 THR A CB  1 
ATOM   6449 O OG1 . THR A 1 934  ? 142.374 147.549 177.940 1.00 75.34  ? 1056 THR A OG1 1 
ATOM   6450 C CG2 . THR A 1 934  ? 143.032 145.428 177.114 1.00 80.77  ? 1056 THR A CG2 1 
ATOM   6451 N N   . SER A 1 935  ? 144.479 146.101 174.139 1.00 81.75  ? 1057 SER A N   1 
ATOM   6452 C CA  . SER A 1 935  ? 144.445 145.542 172.790 1.00 86.73  ? 1057 SER A CA  1 
ATOM   6453 C C   . SER A 1 935  ? 143.042 145.087 172.395 1.00 90.21  ? 1057 SER A C   1 
ATOM   6454 O O   . SER A 1 935  ? 142.692 145.127 171.211 1.00 96.84  ? 1057 SER A O   1 
ATOM   6455 C CB  . SER A 1 935  ? 145.422 144.374 172.680 1.00 87.99  ? 1057 SER A CB  1 
ATOM   6456 O OG  . SER A 1 935  ? 146.763 144.828 172.674 1.00 95.71  ? 1057 SER A OG  1 
ATOM   6457 N N   . SER A 1 936  ? 142.227 144.668 173.362 1.00 82.60  ? 1058 SER A N   1 
ATOM   6458 C CA  . SER A 1 936  ? 140.824 144.358 173.134 1.00 83.54  ? 1058 SER A CA  1 
ATOM   6459 C C   . SER A 1 936  ? 139.918 145.578 173.249 1.00 87.72  ? 1058 SER A C   1 
ATOM   6460 O O   . SER A 1 936  ? 139.205 145.904 172.299 1.00 99.20  ? 1058 SER A O   1 
ATOM   6461 C CB  . SER A 1 936  ? 140.360 143.281 174.120 1.00 88.90  ? 1058 SER A CB  1 
ATOM   6462 O OG  . SER A 1 936  ? 138.987 142.986 173.937 1.00 97.87  ? 1058 SER A OG  1 
ATOM   6463 N N   . GLN A 1 937  ? 139.926 146.268 174.383 1.00 82.22  ? 1059 GLN A N   1 
ATOM   6464 C CA  . GLN A 1 937  ? 138.895 147.257 174.660 1.00 78.74  ? 1059 GLN A CA  1 
ATOM   6465 C C   . GLN A 1 937  ? 139.466 148.668 174.754 1.00 78.10  ? 1059 GLN A C   1 
ATOM   6466 O O   . GLN A 1 937  ? 140.678 148.880 174.797 1.00 82.83  ? 1059 GLN A O   1 
ATOM   6467 C CB  . GLN A 1 937  ? 138.133 146.905 175.944 1.00 76.35  ? 1059 GLN A CB  1 
ATOM   6468 C CG  . GLN A 1 937  ? 138.850 147.255 177.227 1.00 81.85  ? 1059 GLN A CG  1 
ATOM   6469 C CD  . GLN A 1 937  ? 137.964 147.087 178.440 1.00 93.21  ? 1059 GLN A CD  1 
ATOM   6470 O OE1 . GLN A 1 937  ? 136.925 146.432 178.376 1.00 96.12  ? 1059 GLN A OE1 1 
ATOM   6471 N NE2 . GLN A 1 937  ? 138.370 147.678 179.556 1.00 89.20  ? 1059 GLN A NE2 1 
ATOM   6472 N N   . LEU A 1 938  ? 138.558 149.643 174.755 1.00 77.29  ? 1060 LEU A N   1 
ATOM   6473 C CA  . LEU A 1 938  ? 138.878 151.050 174.958 1.00 72.82  ? 1060 LEU A CA  1 
ATOM   6474 C C   . LEU A 1 938  ? 137.901 151.600 175.983 1.00 71.12  ? 1060 LEU A C   1 
ATOM   6475 O O   . LEU A 1 938  ? 136.689 151.566 175.761 1.00 81.87  ? 1060 LEU A O   1 
ATOM   6476 C CB  . LEU A 1 938  ? 138.791 151.828 173.640 1.00 70.71  ? 1060 LEU A CB  1 
ATOM   6477 C CG  . LEU A 1 938  ? 139.332 153.255 173.531 1.00 74.89  ? 1060 LEU A CG  1 
ATOM   6478 C CD1 . LEU A 1 938  ? 140.002 153.398 172.199 1.00 76.65  ? 1060 LEU A CD1 1 
ATOM   6479 C CD2 . LEU A 1 938  ? 138.239 154.299 173.639 1.00 73.99  ? 1060 LEU A CD2 1 
ATOM   6480 N N   . SER A 1 939  ? 138.419 152.118 177.093 1.00 62.29  ? 1061 SER A N   1 
ATOM   6481 C CA  . SER A 1 939  ? 137.566 152.428 178.229 1.00 65.71  ? 1061 SER A CA  1 
ATOM   6482 C C   . SER A 1 939  ? 138.031 153.719 178.892 1.00 65.98  ? 1061 SER A C   1 
ATOM   6483 O O   . SER A 1 939  ? 138.935 154.403 178.406 1.00 73.60  ? 1061 SER A O   1 
ATOM   6484 C CB  . SER A 1 939  ? 137.550 151.263 179.220 1.00 74.04  ? 1061 SER A CB  1 
ATOM   6485 O OG  . SER A 1 939  ? 137.002 151.654 180.466 1.00 78.33  ? 1061 SER A OG  1 
ATOM   6486 N N   . ARG A 1 940  ? 137.387 154.051 180.009 1.00 63.40  ? 1062 ARG A N   1 
ATOM   6487 C CA  . ARG A 1 940  ? 137.649 155.262 180.772 1.00 60.84  ? 1062 ARG A CA  1 
ATOM   6488 C C   . ARG A 1 940  ? 137.708 154.905 182.249 1.00 72.92  ? 1062 ARG A C   1 
ATOM   6489 O O   . ARG A 1 940  ? 136.813 154.223 182.756 1.00 90.30  ? 1062 ARG A O   1 
ATOM   6490 C CB  . ARG A 1 940  ? 136.557 156.311 180.516 1.00 66.99  ? 1062 ARG A CB  1 
ATOM   6491 C CG  . ARG A 1 940  ? 136.548 157.494 181.471 1.00 73.04  ? 1062 ARG A CG  1 
ATOM   6492 C CD  . ARG A 1 940  ? 135.528 158.539 181.071 1.00 78.90  ? 1062 ARG A CD  1 
ATOM   6493 N NE  . ARG A 1 940  ? 134.290 158.467 181.834 1.00 89.01  ? 1062 ARG A NE  1 
ATOM   6494 C CZ  . ARG A 1 940  ? 133.213 159.192 181.565 1.00 97.28  ? 1062 ARG A CZ  1 
ATOM   6495 N NH1 . ARG A 1 940  ? 133.179 160.018 180.533 1.00 87.10  ? 1062 ARG A NH1 1 
ATOM   6496 N NH2 . ARG A 1 940  ? 132.148 159.090 182.354 1.00 108.16 ? 1062 ARG A NH2 1 
ATOM   6497 N N   . HIS A 1 941  ? 138.756 155.348 182.936 1.00 72.55  ? 1063 HIS A N   1 
ATOM   6498 C CA  . HIS A 1 941  ? 138.894 155.154 184.373 1.00 77.24  ? 1063 HIS A CA  1 
ATOM   6499 C C   . HIS A 1 941  ? 138.578 156.461 185.087 1.00 88.92  ? 1063 HIS A C   1 
ATOM   6500 O O   . HIS A 1 941  ? 139.156 157.504 184.763 1.00 88.47  ? 1063 HIS A O   1 
ATOM   6501 C CB  . HIS A 1 941  ? 140.302 154.683 184.727 1.00 78.28  ? 1063 HIS A CB  1 
ATOM   6502 C CG  . HIS A 1 941  ? 140.477 154.342 186.172 1.00 84.60  ? 1063 HIS A CG  1 
ATOM   6503 N ND1 . HIS A 1 941  ? 141.161 155.154 187.050 1.00 86.93  ? 1063 HIS A ND1 1 
ATOM   6504 C CD2 . HIS A 1 941  ? 140.071 153.269 186.890 1.00 86.54  ? 1063 HIS A CD2 1 
ATOM   6505 C CE1 . HIS A 1 941  ? 141.160 154.601 188.249 1.00 86.16  ? 1063 HIS A CE1 1 
ATOM   6506 N NE2 . HIS A 1 941  ? 140.506 153.457 188.179 1.00 86.07  ? 1063 HIS A NE2 1 
ATOM   6507 N N   . GLY A 1 942  ? 137.665 156.405 186.055 1.00 99.73  ? 1064 GLY A N   1 
ATOM   6508 C CA  . GLY A 1 942  ? 137.327 157.550 186.869 1.00 111.07 ? 1064 GLY A CA  1 
ATOM   6509 C C   . GLY A 1 942  ? 137.823 157.410 188.298 1.00 121.60 ? 1064 GLY A C   1 
ATOM   6510 O O   . GLY A 1 942  ? 138.575 156.497 188.646 1.00 124.49 ? 1064 GLY A O   1 
ATOM   6511 N N   . SER A 1 943  ? 137.395 158.356 189.138 1.00 128.56 ? 1065 SER A N   1 
ATOM   6512 C CA  . SER A 1 943  ? 137.721 158.284 190.559 1.00 138.84 ? 1065 SER A CA  1 
ATOM   6513 C C   . SER A 1 943  ? 136.886 157.218 191.260 1.00 143.73 ? 1065 SER A C   1 
ATOM   6514 O O   . SER A 1 943  ? 137.385 156.495 192.131 1.00 141.35 ? 1065 SER A O   1 
ATOM   6515 C CB  . SER A 1 943  ? 137.514 159.648 191.214 1.00 137.31 ? 1065 SER A CB  1 
ATOM   6516 O OG  . SER A 1 943  ? 136.162 160.057 191.115 1.00 134.68 ? 1065 SER A OG  1 
ATOM   6517 N N   . THR A 1 944  ? 135.619 157.111 190.891 1.00 144.42 ? 1066 THR A N   1 
ATOM   6518 C CA  . THR A 1 944  ? 134.678 156.115 191.372 1.00 143.61 ? 1066 THR A CA  1 
ATOM   6519 C C   . THR A 1 944  ? 134.430 155.099 190.261 1.00 140.32 ? 1066 THR A C   1 
ATOM   6520 O O   . THR A 1 944  ? 134.604 155.419 189.079 1.00 136.15 ? 1066 THR A O   1 
ATOM   6521 C CB  . THR A 1 944  ? 133.363 156.796 191.790 1.00 145.88 ? 1066 THR A CB  1 
ATOM   6522 O OG1 . THR A 1 944  ? 132.750 157.404 190.648 1.00 141.31 ? 1066 THR A OG1 1 
ATOM   6523 C CG2 . THR A 1 944  ? 133.628 157.858 192.847 1.00 141.62 ? 1066 THR A CG2 1 
ATOM   6524 N N   . PRO A 1 945  ? 134.022 153.860 190.588 1.00 139.20 ? 1067 PRO A N   1 
ATOM   6525 C CA  . PRO A 1 945  ? 133.691 152.902 189.511 1.00 136.80 ? 1067 PRO A CA  1 
ATOM   6526 C C   . PRO A 1 945  ? 132.310 153.077 188.880 1.00 133.76 ? 1067 PRO A C   1 
ATOM   6527 O O   . PRO A 1 945  ? 131.926 152.243 188.051 1.00 125.55 ? 1067 PRO A O   1 
ATOM   6528 C CB  . PRO A 1 945  ? 133.810 151.537 190.203 1.00 132.23 ? 1067 PRO A CB  1 
ATOM   6529 C CG  . PRO A 1 945  ? 133.606 151.817 191.631 1.00 131.84 ? 1067 PRO A CG  1 
ATOM   6530 C CD  . PRO A 1 945  ? 134.224 153.158 191.872 1.00 135.25 ? 1067 PRO A CD  1 
ATOM   6531 N N   . ASP A 1 946  ? 131.549 154.118 189.235 1.00 135.37 ? 1068 ASP A N   1 
ATOM   6532 C CA  . ASP A 1 946  ? 130.334 154.441 188.494 1.00 135.07 ? 1068 ASP A CA  1 
ATOM   6533 C C   . ASP A 1 946  ? 130.652 155.090 187.152 1.00 127.80 ? 1068 ASP A C   1 
ATOM   6534 O O   . ASP A 1 946  ? 129.838 155.029 186.224 1.00 123.13 ? 1068 ASP A O   1 
ATOM   6535 C CB  . ASP A 1 946  ? 129.443 155.365 189.323 1.00 139.78 ? 1068 ASP A CB  1 
ATOM   6536 C CG  . ASP A 1 946  ? 128.860 154.677 190.539 1.00 144.37 ? 1068 ASP A CG  1 
ATOM   6537 O OD1 . ASP A 1 946  ? 128.710 153.438 190.509 1.00 140.47 ? 1068 ASP A OD1 1 
ATOM   6538 O OD2 . ASP A 1 946  ? 128.552 155.376 191.527 1.00 146.55 ? 1068 ASP A OD2 1 
ATOM   6539 N N   . GLU A 1 947  ? 131.824 155.713 187.030 1.00 124.89 ? 1069 GLU A N   1 
ATOM   6540 C CA  . GLU A 1 947  ? 132.210 156.470 185.848 1.00 119.17 ? 1069 GLU A CA  1 
ATOM   6541 C C   . GLU A 1 947  ? 133.005 155.649 184.841 1.00 110.09 ? 1069 GLU A C   1 
ATOM   6542 O O   . GLU A 1 947  ? 133.629 156.228 183.946 1.00 103.85 ? 1069 GLU A O   1 
ATOM   6543 C CB  . GLU A 1 947  ? 133.022 157.698 186.262 1.00 117.53 ? 1069 GLU A CB  1 
ATOM   6544 C CG  . GLU A 1 947  ? 132.225 158.730 187.035 1.00 121.94 ? 1069 GLU A CG  1 
ATOM   6545 C CD  . GLU A 1 947  ? 133.060 159.923 187.448 1.00 127.35 ? 1069 GLU A CD  1 
ATOM   6546 O OE1 . GLU A 1 947  ? 134.291 159.886 187.241 1.00 128.33 ? 1069 GLU A OE1 1 
ATOM   6547 O OE2 . GLU A 1 947  ? 132.489 160.899 187.977 1.00 129.17 ? 1069 GLU A OE2 1 
ATOM   6548 N N   . ALA A 1 948  ? 133.007 154.325 184.963 1.00 107.22 ? 1070 ALA A N   1 
ATOM   6549 C CA  . ALA A 1 948  ? 133.747 153.478 184.038 1.00 94.69  ? 1070 ALA A CA  1 
ATOM   6550 C C   . ALA A 1 948  ? 132.905 153.216 182.796 1.00 92.80  ? 1070 ALA A C   1 
ATOM   6551 O O   . ALA A 1 948  ? 131.960 152.422 182.835 1.00 104.87 ? 1070 ALA A O   1 
ATOM   6552 C CB  . ALA A 1 948  ? 134.137 152.165 184.711 1.00 95.24  ? 1070 ALA A CB  1 
ATOM   6553 N N   . VAL A 1 949  ? 133.248 153.882 181.694 1.00 78.25  ? 1071 VAL A N   1 
ATOM   6554 C CA  . VAL A 1 949  ? 132.520 153.773 180.434 1.00 81.33  ? 1071 VAL A CA  1 
ATOM   6555 C C   . VAL A 1 949  ? 133.422 153.096 179.416 1.00 78.12  ? 1071 VAL A C   1 
ATOM   6556 O O   . VAL A 1 949  ? 134.519 153.587 179.137 1.00 88.32  ? 1071 VAL A O   1 
ATOM   6557 C CB  . VAL A 1 949  ? 132.064 155.142 179.902 1.00 91.40  ? 1071 VAL A CB  1 
ATOM   6558 C CG1 . VAL A 1 949  ? 131.081 154.956 178.765 1.00 94.71  ? 1071 VAL A CG1 1 
ATOM   6559 C CG2 . VAL A 1 949  ? 131.434 155.968 181.005 1.00 100.80 ? 1071 VAL A CG2 1 
ATOM   6560 N N   . THR A 1 950  ? 132.956 151.988 178.850 1.00 76.09  ? 1072 THR A N   1 
ATOM   6561 C CA  . THR A 1 950  ? 133.692 151.300 177.801 1.00 74.67  ? 1072 THR A CA  1 
ATOM   6562 C C   . THR A 1 950  ? 133.115 151.664 176.438 1.00 75.46  ? 1072 THR A C   1 
ATOM   6563 O O   . THR A 1 950  ? 131.907 151.569 176.205 1.00 84.46  ? 1072 THR A O   1 
ATOM   6564 C CB  . THR A 1 950  ? 133.640 149.786 178.018 1.00 82.75  ? 1072 THR A CB  1 
ATOM   6565 O OG1 . THR A 1 950  ? 134.038 149.487 179.360 1.00 89.03  ? 1072 THR A OG1 1 
ATOM   6566 C CG2 . THR A 1 950  ? 134.579 149.062 177.065 1.00 79.38  ? 1072 THR A CG2 1 
ATOM   6567 N N   . TYR A 1 951  ? 133.989 152.089 175.538 1.00 72.96  ? 1073 TYR A N   1 
ATOM   6568 C CA  . TYR A 1 951  ? 133.588 152.658 174.258 1.00 71.37  ? 1073 TYR A CA  1 
ATOM   6569 C C   . TYR A 1 951  ? 133.678 151.674 173.102 1.00 74.74  ? 1073 TYR A C   1 
ATOM   6570 O O   . TYR A 1 951  ? 132.912 151.791 172.145 1.00 82.72  ? 1073 TYR A O   1 
ATOM   6571 C CB  . TYR A 1 951  ? 134.454 153.889 173.971 1.00 71.54  ? 1073 TYR A CB  1 
ATOM   6572 C CG  . TYR A 1 951  ? 134.209 155.020 174.938 1.00 74.02  ? 1073 TYR A CG  1 
ATOM   6573 C CD1 . TYR A 1 951  ? 133.058 155.808 174.840 1.00 80.31  ? 1073 TYR A CD1 1 
ATOM   6574 C CD2 . TYR A 1 951  ? 135.116 155.285 175.968 1.00 75.38  ? 1073 TYR A CD2 1 
ATOM   6575 C CE1 . TYR A 1 951  ? 132.823 156.847 175.738 1.00 84.69  ? 1073 TYR A CE1 1 
ATOM   6576 C CE2 . TYR A 1 951  ? 134.892 156.319 176.873 1.00 77.73  ? 1073 TYR A CE2 1 
ATOM   6577 C CZ  . TYR A 1 951  ? 133.745 157.090 176.747 1.00 82.00  ? 1073 TYR A CZ  1 
ATOM   6578 O OH  . TYR A 1 951  ? 133.518 158.113 177.634 1.00 91.00  ? 1073 TYR A OH  1 
ATOM   6579 N N   . TYR A 1 952  ? 134.594 150.713 173.163 1.00 71.37  ? 1074 TYR A N   1 
ATOM   6580 C CA  . TYR A 1 952  ? 134.798 149.773 172.072 1.00 69.91  ? 1074 TYR A CA  1 
ATOM   6581 C C   . TYR A 1 952  ? 135.257 148.447 172.650 1.00 81.99  ? 1074 TYR A C   1 
ATOM   6582 O O   . TYR A 1 952  ? 135.888 148.411 173.704 1.00 88.17  ? 1074 TYR A O   1 
ATOM   6583 C CB  . TYR A 1 952  ? 135.834 150.298 171.080 1.00 72.32  ? 1074 TYR A CB  1 
ATOM   6584 C CG  . TYR A 1 952  ? 135.903 149.548 169.773 1.00 77.40  ? 1074 TYR A CG  1 
ATOM   6585 C CD1 . TYR A 1 952  ? 134.779 149.443 168.947 1.00 81.70  ? 1074 TYR A CD1 1 
ATOM   6586 C CD2 . TYR A 1 952  ? 137.097 148.949 169.360 1.00 85.65  ? 1074 TYR A CD2 1 
ATOM   6587 C CE1 . TYR A 1 952  ? 134.841 148.751 167.737 1.00 87.55  ? 1074 TYR A CE1 1 
ATOM   6588 C CE2 . TYR A 1 952  ? 137.172 148.257 168.153 1.00 89.38  ? 1074 TYR A CE2 1 
ATOM   6589 C CZ  . TYR A 1 952  ? 136.042 148.165 167.353 1.00 91.69  ? 1074 TYR A CZ  1 
ATOM   6590 O OH  . TYR A 1 952  ? 136.115 147.481 166.163 1.00 95.75  ? 1074 TYR A OH  1 
ATOM   6591 N N   . ARG A 1 953  ? 134.901 147.356 171.968 1.00 88.22  ? 1075 ARG A N   1 
ATOM   6592 C CA  . ARG A 1 953  ? 135.408 146.015 172.245 1.00 84.40  ? 1075 ARG A CA  1 
ATOM   6593 C C   . ARG A 1 953  ? 135.629 145.315 170.914 1.00 89.24  ? 1075 ARG A C   1 
ATOM   6594 O O   . ARG A 1 953  ? 134.773 145.393 170.030 1.00 97.43  ? 1075 ARG A O   1 
ATOM   6595 C CB  . ARG A 1 953  ? 134.434 145.191 173.102 1.00 80.54  ? 1075 ARG A CB  1 
ATOM   6596 C CG  . ARG A 1 953  ? 134.346 145.576 174.570 1.00 83.15  ? 1075 ARG A CG  1 
ATOM   6597 C CD  . ARG A 1 953  ? 133.481 144.621 175.360 1.00 95.97  ? 1075 ARG A CD  1 
ATOM   6598 N NE  . ARG A 1 953  ? 133.347 145.049 176.746 1.00 103.22 ? 1075 ARG A NE  1 
ATOM   6599 C CZ  . ARG A 1 953  ? 132.395 145.860 177.188 1.00 101.33 ? 1075 ARG A CZ  1 
ATOM   6600 N NH1 . ARG A 1 953  ? 131.476 146.355 176.376 1.00 97.85  ? 1075 ARG A NH1 1 
ATOM   6601 N NH2 . ARG A 1 953  ? 132.365 146.181 178.479 1.00 96.17  ? 1075 ARG A NH2 1 
ATOM   6602 N N   . VAL A 1 954  ? 136.763 144.635 170.764 1.00 90.41  ? 1076 VAL A N   1 
ATOM   6603 C CA  . VAL A 1 954  ? 137.035 143.843 169.570 1.00 102.40 ? 1076 VAL A CA  1 
ATOM   6604 C C   . VAL A 1 954  ? 137.644 142.511 170.009 1.00 113.67 ? 1076 VAL A C   1 
ATOM   6605 O O   . VAL A 1 954  ? 138.332 142.433 171.033 1.00 112.12 ? 1076 VAL A O   1 
ATOM   6606 C CB  . VAL A 1 954  ? 137.924 144.630 168.560 1.00 102.82 ? 1076 VAL A CB  1 
ATOM   6607 C CG1 . VAL A 1 954  ? 139.336 144.932 169.072 1.00 97.64  ? 1076 VAL A CG1 1 
ATOM   6608 C CG2 . VAL A 1 954  ? 137.947 144.009 167.153 1.00 115.88 ? 1076 VAL A CG2 1 
ATOM   6609 N N   . ASN A 1 955  ? 137.288 141.440 169.299 1.00 124.91 ? 1077 ASN A N   1 
ATOM   6610 C CA  . ASN A 1 955  ? 137.914 140.143 169.508 1.00 131.99 ? 1077 ASN A CA  1 
ATOM   6611 C C   . ASN A 1 955  ? 139.343 140.176 168.974 1.00 132.74 ? 1077 ASN A C   1 
ATOM   6612 O O   . ASN A 1 955  ? 139.649 140.888 168.015 1.00 131.01 ? 1077 ASN A O   1 
ATOM   6613 C CB  . ASN A 1 955  ? 137.095 139.050 168.812 1.00 133.72 ? 1077 ASN A CB  1 
ATOM   6614 C CG  . ASN A 1 955  ? 137.523 137.647 169.203 1.00 136.43 ? 1077 ASN A CG  1 
ATOM   6615 O OD1 . ASN A 1 955  ? 137.876 137.392 170.354 1.00 136.44 ? 1077 ASN A OD1 1 
ATOM   6616 N ND2 . ASN A 1 955  ? 137.499 136.732 168.243 1.00 133.38 ? 1077 ASN A ND2 1 
ATOM   6617 N N   . GLY A 1 956  ? 140.224 139.401 169.618 1.00 134.31 ? 1078 GLY A N   1 
ATOM   6618 C CA  . GLY A 1 956  ? 141.638 139.442 169.272 1.00 133.73 ? 1078 GLY A CA  1 
ATOM   6619 C C   . GLY A 1 956  ? 141.968 138.730 167.972 1.00 136.81 ? 1078 GLY A C   1 
ATOM   6620 O O   . GLY A 1 956  ? 143.009 138.983 167.362 1.00 136.10 ? 1078 GLY A O   1 
ATOM   6621 N N   . LEU A 1 957  ? 141.090 137.824 167.533 1.00 138.87 ? 1079 LEU A N   1 
ATOM   6622 C CA  . LEU A 1 957  ? 141.257 137.222 166.215 1.00 140.97 ? 1079 LEU A CA  1 
ATOM   6623 C C   . LEU A 1 957  ? 140.832 138.186 165.115 1.00 137.52 ? 1079 LEU A C   1 
ATOM   6624 O O   . LEU A 1 957  ? 141.325 138.104 163.984 1.00 136.30 ? 1079 LEU A O   1 
ATOM   6625 C CB  . LEU A 1 957  ? 140.464 135.918 166.128 1.00 144.46 ? 1079 LEU A CB  1 
ATOM   6626 C CG  . LEU A 1 957  ? 140.744 134.866 167.203 1.00 143.30 ? 1079 LEU A CG  1 
ATOM   6627 C CD1 . LEU A 1 957  ? 139.909 133.621 166.959 1.00 137.04 ? 1079 LEU A CD1 1 
ATOM   6628 C CD2 . LEU A 1 957  ? 142.224 134.518 167.259 1.00 134.87 ? 1079 LEU A CD2 1 
ATOM   6629 N N   . GLU A 1 958  ? 139.905 139.098 165.426 1.00 135.58 ? 1080 GLU A N   1 
ATOM   6630 C CA  . GLU A 1 958  ? 139.495 140.108 164.455 1.00 136.09 ? 1080 GLU A CA  1 
ATOM   6631 C C   . GLU A 1 958  ? 140.560 141.185 164.295 1.00 135.39 ? 1080 GLU A C   1 
ATOM   6632 O O   . GLU A 1 958  ? 140.839 141.630 163.176 1.00 133.01 ? 1080 GLU A O   1 
ATOM   6633 C CB  . GLU A 1 958  ? 138.167 140.734 164.878 1.00 130.72 ? 1080 GLU A CB  1 
ATOM   6634 C CG  . GLU A 1 958  ? 137.037 139.739 165.065 1.00 134.05 ? 1080 GLU A CG  1 
ATOM   6635 C CD  . GLU A 1 958  ? 135.799 140.373 165.667 1.00 135.50 ? 1080 GLU A CD  1 
ATOM   6636 O OE1 . GLU A 1 958  ? 135.839 141.579 165.987 1.00 130.53 ? 1080 GLU A OE1 1 
ATOM   6637 O OE2 . GLU A 1 958  ? 134.783 139.664 165.821 1.00 134.37 ? 1080 GLU A OE2 1 
ATOM   6638 N N   . GLY A 1 959  ? 141.161 141.613 165.395 1.00 133.19 ? 1081 GLY A N   1 
ATOM   6639 C CA  . GLY A 1 959  ? 142.201 142.616 165.333 1.00 122.95 ? 1081 GLY A CA  1 
ATOM   6640 C C   . GLY A 1 959  ? 142.479 143.194 166.708 1.00 121.37 ? 1081 GLY A C   1 
ATOM   6641 O O   . GLY A 1 959  ? 141.971 142.718 167.721 1.00 125.74 ? 1081 GLY A O   1 
ATOM   6642 N N   . SER A 1 960  ? 143.303 144.238 166.710 1.00 114.48 ? 1082 SER A N   1 
ATOM   6643 C CA  . SER A 1 960  ? 143.691 144.919 167.934 1.00 104.35 ? 1082 SER A CA  1 
ATOM   6644 C C   . SER A 1 960  ? 143.698 146.419 167.689 1.00 100.22 ? 1082 SER A C   1 
ATOM   6645 O O   . SER A 1 960  ? 143.815 146.872 166.548 1.00 102.61 ? 1082 SER A O   1 
ATOM   6646 C CB  . SER A 1 960  ? 145.071 144.464 168.420 1.00 103.07 ? 1082 SER A CB  1 
ATOM   6647 O OG  . SER A 1 960  ? 146.066 144.760 167.459 1.00 107.18 ? 1082 SER A OG  1 
ATOM   6648 N N   . ILE A 1 961  ? 143.567 147.185 168.771 1.00 92.23  ? 1083 ILE A N   1 
ATOM   6649 C CA  . ILE A 1 961  ? 143.609 148.638 168.668 1.00 84.68  ? 1083 ILE A CA  1 
ATOM   6650 C C   . ILE A 1 961  ? 145.052 149.089 168.499 1.00 85.05  ? 1083 ILE A C   1 
ATOM   6651 O O   . ILE A 1 961  ? 145.921 148.769 169.319 1.00 89.43  ? 1083 ILE A O   1 
ATOM   6652 C CB  . ILE A 1 961  ? 142.963 149.286 169.899 1.00 80.37  ? 1083 ILE A CB  1 
ATOM   6653 C CG1 . ILE A 1 961  ? 141.606 148.641 170.182 1.00 81.11  ? 1083 ILE A CG1 1 
ATOM   6654 C CG2 . ILE A 1 961  ? 142.824 150.784 169.690 1.00 84.55  ? 1083 ILE A CG2 1 
ATOM   6655 C CD1 . ILE A 1 961  ? 140.901 149.190 171.401 1.00 74.57  ? 1083 ILE A CD1 1 
ATOM   6656 N N   . ALA A 1 962  ? 145.315 149.834 167.427 1.00 80.39  ? 1084 ALA A N   1 
ATOM   6657 C CA  . ALA A 1 962  ? 146.670 150.246 167.090 1.00 82.18  ? 1084 ALA A CA  1 
ATOM   6658 C C   . ALA A 1 962  ? 147.123 151.494 167.826 1.00 86.22  ? 1084 ALA A C   1 
ATOM   6659 O O   . ALA A 1 962  ? 148.269 151.541 168.274 1.00 92.02  ? 1084 ALA A O   1 
ATOM   6660 C CB  . ALA A 1 962  ? 146.793 150.481 165.582 1.00 87.13  ? 1084 ALA A CB  1 
ATOM   6661 N N   . SER A 1 963  ? 146.258 152.500 167.944 1.00 79.43  ? 1085 SER A N   1 
ATOM   6662 C CA  . SER A 1 963  ? 146.504 153.724 168.698 1.00 76.23  ? 1085 SER A CA  1 
ATOM   6663 C C   . SER A 1 963  ? 145.153 154.342 169.004 1.00 72.67  ? 1085 SER A C   1 
ATOM   6664 O O   . SER A 1 963  ? 144.140 153.934 168.437 1.00 79.35  ? 1085 SER A O   1 
ATOM   6665 C CB  . SER A 1 963  ? 147.372 154.720 167.926 1.00 76.76  ? 1085 SER A CB  1 
ATOM   6666 O OG  . SER A 1 963  ? 147.748 155.807 168.751 1.00 88.09  ? 1085 SER A OG  1 
ATOM   6667 N N   . PHE A 1 964  ? 145.140 155.327 169.905 1.00 71.03  ? 1086 PHE A N   1 
ATOM   6668 C CA  . PHE A 1 964  ? 143.927 156.108 170.107 1.00 69.34  ? 1086 PHE A CA  1 
ATOM   6669 C C   . PHE A 1 964  ? 144.271 157.545 170.472 1.00 71.32  ? 1086 PHE A C   1 
ATOM   6670 O O   . PHE A 1 964  ? 145.349 157.832 170.995 1.00 77.00  ? 1086 PHE A O   1 
ATOM   6671 C CB  . PHE A 1 964  ? 142.988 155.483 171.159 1.00 66.99  ? 1086 PHE A CB  1 
ATOM   6672 C CG  . PHE A 1 964  ? 143.223 155.929 172.569 1.00 69.04  ? 1086 PHE A CG  1 
ATOM   6673 C CD1 . PHE A 1 964  ? 144.332 155.477 173.283 1.00 70.58  ? 1086 PHE A CD1 1 
ATOM   6674 C CD2 . PHE A 1 964  ? 142.288 156.754 173.205 1.00 64.79  ? 1086 PHE A CD2 1 
ATOM   6675 C CE1 . PHE A 1 964  ? 144.532 155.874 174.596 1.00 70.17  ? 1086 PHE A CE1 1 
ATOM   6676 C CE2 . PHE A 1 964  ? 142.481 157.160 174.515 1.00 65.72  ? 1086 PHE A CE2 1 
ATOM   6677 C CZ  . PHE A 1 964  ? 143.602 156.716 175.209 1.00 70.93  ? 1086 PHE A CZ  1 
ATOM   6678 N N   . VAL A 1 965  ? 143.336 158.450 170.163 1.00 66.48  ? 1087 VAL A N   1 
ATOM   6679 C CA  . VAL A 1 965  ? 143.453 159.886 170.404 1.00 60.90  ? 1087 VAL A CA  1 
ATOM   6680 C C   . VAL A 1 965  ? 142.200 160.366 171.131 1.00 69.37  ? 1087 VAL A C   1 
ATOM   6681 O O   . VAL A 1 965  ? 141.084 160.172 170.642 1.00 80.24  ? 1087 VAL A O   1 
ATOM   6682 C CB  . VAL A 1 965  ? 143.638 160.674 169.082 1.00 68.08  ? 1087 VAL A CB  1 
ATOM   6683 C CG1 . VAL A 1 965  ? 143.519 162.158 169.301 1.00 78.98  ? 1087 VAL A CG1 1 
ATOM   6684 C CG2 . VAL A 1 965  ? 144.985 160.413 168.469 1.00 72.04  ? 1087 VAL A CG2 1 
ATOM   6685 N N   . LEU A 1 966  ? 142.382 160.991 172.293 1.00 70.39  ? 1088 LEU A N   1 
ATOM   6686 C CA  . LEU A 1 966  ? 141.317 161.719 172.970 1.00 72.82  ? 1088 LEU A CA  1 
ATOM   6687 C C   . LEU A 1 966  ? 141.283 163.162 172.488 1.00 74.87  ? 1088 LEU A C   1 
ATOM   6688 O O   . LEU A 1 966  ? 142.312 163.845 172.490 1.00 76.58  ? 1088 LEU A O   1 
ATOM   6689 C CB  . LEU A 1 966  ? 141.519 161.687 174.483 1.00 72.58  ? 1088 LEU A CB  1 
ATOM   6690 C CG  . LEU A 1 966  ? 140.664 162.603 175.350 1.00 69.98  ? 1088 LEU A CG  1 
ATOM   6691 C CD1 . LEU A 1 966  ? 139.263 162.068 175.441 1.00 74.09  ? 1088 LEU A CD1 1 
ATOM   6692 C CD2 . LEU A 1 966  ? 141.283 162.739 176.717 1.00 70.83  ? 1088 LEU A CD2 1 
ATOM   6693 N N   . ASP A 1 967  ? 140.102 163.627 172.084 1.00 84.47  ? 1089 ASP A N   1 
ATOM   6694 C CA  . ASP A 1 967  ? 139.884 165.017 171.697 1.00 85.74  ? 1089 ASP A CA  1 
ATOM   6695 C C   . ASP A 1 967  ? 139.128 165.593 172.894 1.00 89.08  ? 1089 ASP A C   1 
ATOM   6696 O O   . ASP A 1 967  ? 138.159 164.998 173.371 1.00 95.36  ? 1089 ASP A O   1 
ATOM   6697 C CB  . ASP A 1 967  ? 139.125 165.075 170.357 1.00 87.83  ? 1089 ASP A CB  1 
ATOM   6698 C CG  . ASP A 1 967  ? 138.606 166.494 169.905 1.00 101.94 ? 1089 ASP A CG  1 
ATOM   6699 O OD1 . ASP A 1 967  ? 138.297 166.560 168.697 1.00 102.53 ? 1089 ASP A OD1 1 
ATOM   6700 O OD2 . ASP A 1 967  ? 138.543 167.546 170.585 1.00 106.47 ? 1089 ASP A OD2 1 
ATOM   6701 N N   . THR A 1 968  ? 139.572 166.758 173.357 1.00 89.36  ? 1090 THR A N   1 
ATOM   6702 C CA  . THR A 1 968  ? 139.043 167.434 174.533 1.00 94.64  ? 1090 THR A CA  1 
ATOM   6703 C C   . THR A 1 968  ? 138.026 168.507 174.152 1.00 98.80  ? 1090 THR A C   1 
ATOM   6704 O O   . THR A 1 968  ? 136.960 168.606 174.777 1.00 103.65 ? 1090 THR A O   1 
ATOM   6705 C CB  . THR A 1 968  ? 140.223 168.031 175.322 1.00 99.14  ? 1090 THR A CB  1 
ATOM   6706 O OG1 . THR A 1 968  ? 141.053 166.970 175.807 1.00 91.84  ? 1090 THR A OG1 1 
ATOM   6707 C CG2 . THR A 1 968  ? 139.789 168.891 176.510 1.00 95.32  ? 1090 THR A CG2 1 
ATOM   6708 N N   . GLN A 1 969  ? 138.321 169.262 173.089 1.00 97.85  ? 1091 GLN A N   1 
ATOM   6709 C CA  . GLN A 1 969  ? 137.558 170.461 172.749 1.00 98.96  ? 1091 GLN A CA  1 
ATOM   6710 C C   . GLN A 1 969  ? 136.210 170.125 172.118 1.00 98.90  ? 1091 GLN A C   1 
ATOM   6711 O O   . GLN A 1 969  ? 135.198 170.762 172.432 1.00 101.29 ? 1091 GLN A O   1 
ATOM   6712 C CB  . GLN A 1 969  ? 138.386 171.336 171.811 1.00 99.45  ? 1091 GLN A CB  1 
ATOM   6713 C CG  . GLN A 1 969  ? 139.703 171.802 172.410 1.00 96.95  ? 1091 GLN A CG  1 
ATOM   6714 C CD  . GLN A 1 969  ? 140.584 172.511 171.402 1.00 104.58 ? 1091 GLN A CD  1 
ATOM   6715 O OE1 . GLN A 1 969  ? 140.183 172.735 170.260 1.00 107.35 ? 1091 GLN A OE1 1 
ATOM   6716 N NE2 . GLN A 1 969  ? 141.797 172.857 171.814 1.00 105.66 ? 1091 GLN A NE2 1 
ATOM   6717 N N   . GLN A 1 970  ? 136.175 169.135 171.230 1.00 96.59  ? 1092 GLN A N   1 
ATOM   6718 C CA  . GLN A 1 970  ? 134.942 168.728 170.574 1.00 97.56  ? 1092 GLN A CA  1 
ATOM   6719 C C   . GLN A 1 970  ? 134.296 167.511 171.221 1.00 101.68 ? 1092 GLN A C   1 
ATOM   6720 O O   . GLN A 1 970  ? 133.251 167.063 170.730 1.00 108.51 ? 1092 GLN A O   1 
ATOM   6721 C CB  . GLN A 1 970  ? 135.199 168.464 169.089 1.00 96.18  ? 1092 GLN A CB  1 
ATOM   6722 C CG  . GLN A 1 970  ? 135.901 169.610 168.384 1.00 104.78 ? 1092 GLN A CG  1 
ATOM   6723 C CD  . GLN A 1 970  ? 135.049 170.869 168.334 1.00 112.38 ? 1092 GLN A CD  1 
ATOM   6724 O OE1 . GLN A 1 970  ? 133.840 170.806 168.111 1.00 113.81 ? 1092 GLN A OE1 1 
ATOM   6725 N NE2 . GLN A 1 970  ? 135.679 172.017 168.551 1.00 104.68 ? 1092 GLN A NE2 1 
ATOM   6726 N N   . ASP A 1 971  ? 134.893 167.004 172.313 1.00 93.73  ? 1093 ASP A N   1 
ATOM   6727 C CA  . ASP A 1 971  ? 134.462 165.857 173.135 1.00 86.45  ? 1093 ASP A CA  1 
ATOM   6728 C C   . ASP A 1 971  ? 134.305 164.580 172.310 1.00 84.09  ? 1093 ASP A C   1 
ATOM   6729 O O   . ASP A 1 971  ? 133.236 163.977 172.232 1.00 89.01  ? 1093 ASP A O   1 
ATOM   6730 C CB  . ASP A 1 971  ? 133.186 166.171 173.920 1.00 94.08  ? 1093 ASP A CB  1 
ATOM   6731 C CG  . ASP A 1 971  ? 133.388 167.263 174.943 1.00 102.77 ? 1093 ASP A CG  1 
ATOM   6732 O OD1 . ASP A 1 971  ? 133.561 168.431 174.539 1.00 105.13 ? 1093 ASP A OD1 1 
ATOM   6733 O OD2 . ASP A 1 971  ? 133.373 166.957 176.153 1.00 104.32 ? 1093 ASP A OD2 1 
ATOM   6734 N N   . GLN A 1 972  ? 135.407 164.179 171.683 1.00 81.99  ? 1094 GLN A N   1 
ATOM   6735 C CA  . GLN A 1 972  ? 135.421 163.087 170.722 1.00 84.43  ? 1094 GLN A CA  1 
ATOM   6736 C C   . GLN A 1 972  ? 136.562 162.139 171.059 1.00 86.35  ? 1094 GLN A C   1 
ATOM   6737 O O   . GLN A 1 972  ? 137.492 162.488 171.787 1.00 90.05  ? 1094 GLN A O   1 
ATOM   6738 C CB  . GLN A 1 972  ? 135.562 163.614 169.276 1.00 93.68  ? 1094 GLN A CB  1 
ATOM   6739 C CG  . GLN A 1 972  ? 134.360 164.417 168.772 1.00 103.30 ? 1094 GLN A CG  1 
ATOM   6740 C CD  . GLN A 1 972  ? 134.520 164.954 167.368 1.00 110.56 ? 1094 GLN A CD  1 
ATOM   6741 O OE1 . GLN A 1 972  ? 135.562 164.800 166.749 1.00 105.97 ? 1094 GLN A OE1 1 
ATOM   6742 N NE2 . GLN A 1 972  ? 133.479 165.607 166.865 1.00 117.14 ? 1094 GLN A NE2 1 
ATOM   6743 N N   . LEU A 1 973  ? 136.461 160.917 170.546 1.00 82.35  ? 1095 LEU A N   1 
ATOM   6744 C CA  . LEU A 1 973  ? 137.531 159.932 170.613 1.00 69.90  ? 1095 LEU A CA  1 
ATOM   6745 C C   . LEU A 1 973  ? 137.757 159.395 169.214 1.00 73.34  ? 1095 LEU A C   1 
ATOM   6746 O O   . LEU A 1 973  ? 136.806 159.276 168.445 1.00 89.44  ? 1095 LEU A O   1 
ATOM   6747 C CB  . LEU A 1 973  ? 137.186 158.774 171.553 1.00 75.67  ? 1095 LEU A CB  1 
ATOM   6748 C CG  . LEU A 1 973  ? 137.582 158.853 173.023 1.00 80.66  ? 1095 LEU A CG  1 
ATOM   6749 C CD1 . LEU A 1 973  ? 136.791 157.842 173.817 1.00 73.51  ? 1095 LEU A CD1 1 
ATOM   6750 C CD2 . LEU A 1 973  ? 139.065 158.609 173.194 1.00 81.12  ? 1095 LEU A CD2 1 
ATOM   6751 N N   . PHE A 1 974  ? 139.002 159.097 168.877 1.00 69.65  ? 1096 PHE A N   1 
ATOM   6752 C CA  . PHE A 1 974  ? 139.339 158.384 167.654 1.00 71.22  ? 1096 PHE A CA  1 
ATOM   6753 C C   . PHE A 1 974  ? 140.258 157.238 168.014 1.00 73.56  ? 1096 PHE A C   1 
ATOM   6754 O O   . PHE A 1 974  ? 141.037 157.352 168.958 1.00 80.85  ? 1096 PHE A O   1 
ATOM   6755 C CB  . PHE A 1 974  ? 140.041 159.276 166.637 1.00 73.29  ? 1096 PHE A CB  1 
ATOM   6756 C CG  . PHE A 1 974  ? 139.325 160.550 166.347 1.00 75.03  ? 1096 PHE A CG  1 
ATOM   6757 C CD1 . PHE A 1 974  ? 138.246 160.561 165.463 1.00 75.70  ? 1096 PHE A CD1 1 
ATOM   6758 C CD2 . PHE A 1 974  ? 139.737 161.741 166.944 1.00 79.98  ? 1096 PHE A CD2 1 
ATOM   6759 C CE1 . PHE A 1 974  ? 137.582 161.743 165.178 1.00 77.84  ? 1096 PHE A CE1 1 
ATOM   6760 C CE2 . PHE A 1 974  ? 139.077 162.929 166.672 1.00 84.65  ? 1096 PHE A CE2 1 
ATOM   6761 C CZ  . PHE A 1 974  ? 138.003 162.923 165.783 1.00 81.80  ? 1096 PHE A CZ  1 
ATOM   6762 N N   . TRP A 1 975  ? 140.167 156.135 167.268 1.00 73.54  ? 1097 TRP A N   1 
ATOM   6763 C CA  . TRP A 1 975  ? 141.119 155.047 167.426 1.00 76.67  ? 1097 TRP A CA  1 
ATOM   6764 C C   . TRP A 1 975  ? 141.297 154.297 166.118 1.00 79.45  ? 1097 TRP A C   1 
ATOM   6765 O O   . TRP A 1 975  ? 140.386 154.242 165.290 1.00 88.16  ? 1097 TRP A O   1 
ATOM   6766 C CB  . TRP A 1 975  ? 140.710 154.064 168.532 1.00 77.77  ? 1097 TRP A CB  1 
ATOM   6767 C CG  . TRP A 1 975  ? 139.397 153.402 168.377 1.00 73.21  ? 1097 TRP A CG  1 
ATOM   6768 C CD1 . TRP A 1 975  ? 139.160 152.186 167.825 1.00 74.53  ? 1097 TRP A CD1 1 
ATOM   6769 C CD2 . TRP A 1 975  ? 138.132 153.902 168.812 1.00 73.04  ? 1097 TRP A CD2 1 
ATOM   6770 N NE1 . TRP A 1 975  ? 137.823 151.894 167.877 1.00 79.39  ? 1097 TRP A NE1 1 
ATOM   6771 C CE2 . TRP A 1 975  ? 137.170 152.928 168.490 1.00 74.41  ? 1097 TRP A CE2 1 
ATOM   6772 C CE3 . TRP A 1 975  ? 137.719 155.078 169.447 1.00 76.74  ? 1097 TRP A CE3 1 
ATOM   6773 C CZ2 . TRP A 1 975  ? 135.816 153.105 168.753 1.00 78.77  ? 1097 TRP A CZ2 1 
ATOM   6774 C CZ3 . TRP A 1 975  ? 136.372 155.245 169.722 1.00 77.41  ? 1097 TRP A CZ3 1 
ATOM   6775 C CH2 . TRP A 1 975  ? 135.440 154.259 169.376 1.00 77.90  ? 1097 TRP A CH2 1 
ATOM   6776 N N   . LEU A 1 976  ? 142.484 153.725 165.947 1.00 81.03  ? 1098 LEU A N   1 
ATOM   6777 C CA  . LEU A 1 976  ? 142.811 152.875 164.813 1.00 81.18  ? 1098 LEU A CA  1 
ATOM   6778 C C   . LEU A 1 976  ? 142.767 151.419 165.244 1.00 89.06  ? 1098 LEU A C   1 
ATOM   6779 O O   . LEU A 1 976  ? 143.297 151.060 166.297 1.00 91.41  ? 1098 LEU A O   1 
ATOM   6780 C CB  . LEU A 1 976  ? 144.202 153.196 164.265 1.00 80.55  ? 1098 LEU A CB  1 
ATOM   6781 C CG  . LEU A 1 976  ? 144.369 154.347 163.281 1.00 81.90  ? 1098 LEU A CG  1 
ATOM   6782 C CD1 . LEU A 1 976  ? 145.841 154.538 162.978 1.00 83.84  ? 1098 LEU A CD1 1 
ATOM   6783 C CD2 . LEU A 1 976  ? 143.596 154.076 162.010 1.00 89.85  ? 1098 LEU A CD2 1 
ATOM   6784 N N   . VAL A 1 977  ? 142.140 150.581 164.427 1.00 92.24  ? 1099 VAL A N   1 
ATOM   6785 C CA  . VAL A 1 977  ? 142.079 149.145 164.676 1.00 91.74  ? 1099 VAL A CA  1 
ATOM   6786 C C   . VAL A 1 977  ? 142.892 148.456 163.592 1.00 98.63  ? 1099 VAL A C   1 
ATOM   6787 O O   . VAL A 1 977  ? 142.570 148.554 162.403 1.00 105.57 ? 1099 VAL A O   1 
ATOM   6788 C CB  . VAL A 1 977  ? 140.638 148.626 164.705 1.00 89.68  ? 1099 VAL A CB  1 
ATOM   6789 C CG1 . VAL A 1 977  ? 140.632 147.120 164.860 1.00 101.27 ? 1099 VAL A CG1 1 
ATOM   6790 C CG2 . VAL A 1 977  ? 139.883 149.264 165.840 1.00 85.30  ? 1099 VAL A CG2 1 
ATOM   6791 N N   . LYS A 1 978  ? 143.953 147.764 164.010 1.00 103.53 ? 1100 LYS A N   1 
ATOM   6792 C CA  . LYS A 1 978  ? 144.793 146.987 163.068 1.00 110.53 ? 1100 LYS A CA  1 
ATOM   6793 C C   . LYS A 1 978  ? 144.098 145.654 162.854 1.00 115.64 ? 1100 LYS A C   1 
ATOM   6794 O O   . LYS A 1 978  ? 144.195 144.789 163.736 1.00 116.64 ? 1100 LYS A O   1 
ATOM   6795 C CB  . LYS A 1 978  ? 146.169 146.709 163.668 1.00 113.81 ? 1100 LYS A CB  1 
ATOM   6796 C CG  . LYS A 1 978  ? 147.068 145.796 162.846 1.00 124.59 ? 1100 LYS A CG  1 
ATOM   6797 C CD  . LYS A 1 978  ? 148.116 145.100 163.683 1.00 126.97 ? 1100 LYS A CD  1 
ATOM   6798 C CE  . LYS A 1 978  ? 148.829 143.993 162.938 1.00 122.39 ? 1100 LYS A CE  1 
ATOM   6799 N NZ  . LYS A 1 978  ? 149.871 143.355 163.776 1.00 120.03 ? 1100 LYS A NZ  1 
ATOM   6800 N N   . GLY A 1 979  ? 143.400 145.518 161.737 1.00 120.48 ? 1101 GLY A N   1 
ATOM   6801 C CA  . GLY A 1 979  ? 142.674 144.311 161.428 1.00 121.84 ? 1101 GLY A CA  1 
ATOM   6802 C C   . GLY A 1 979  ? 143.512 143.302 160.665 1.00 126.00 ? 1101 GLY A C   1 
ATOM   6803 O O   . GLY A 1 979  ? 144.701 143.497 160.405 1.00 126.33 ? 1101 GLY A O   1 
ATOM   6804 N N   . SER A 1 980  ? 142.861 142.199 160.308 1.00 127.38 ? 1102 SER A N   1 
ATOM   6805 C CA  . SER A 1 980  ? 143.485 141.156 159.500 1.00 131.05 ? 1102 SER A CA  1 
ATOM   6806 C C   . SER A 1 980  ? 143.475 141.618 158.049 1.00 130.37 ? 1102 SER A C   1 
ATOM   6807 O O   . SER A 1 980  ? 142.474 141.474 157.346 1.00 126.99 ? 1102 SER A O   1 
ATOM   6808 C CB  . SER A 1 980  ? 142.751 139.833 159.669 1.00 130.18 ? 1102 SER A CB  1 
ATOM   6809 O OG  . SER A 1 980  ? 141.348 140.022 159.600 1.00 127.18 ? 1102 SER A OG  1 
ATOM   6810 N N   . GLY A 1 981  ? 144.592 142.187 157.602 1.00 129.69 ? 1103 GLY A N   1 
ATOM   6811 C CA  . GLY A 1 981  ? 144.681 142.742 156.267 1.00 124.84 ? 1103 GLY A CA  1 
ATOM   6812 C C   . GLY A 1 981  ? 143.928 144.035 156.063 1.00 130.48 ? 1103 GLY A C   1 
ATOM   6813 O O   . GLY A 1 981  ? 143.613 144.375 154.917 1.00 130.97 ? 1103 GLY A O   1 
ATOM   6814 N N   . ALA A 1 982  ? 143.628 144.768 157.133 1.00 133.80 ? 1104 ALA A N   1 
ATOM   6815 C CA  . ALA A 1 982  ? 142.830 145.979 157.034 1.00 127.10 ? 1104 ALA A CA  1 
ATOM   6816 C C   . ALA A 1 982  ? 143.252 146.947 158.129 1.00 126.43 ? 1104 ALA A C   1 
ATOM   6817 O O   . ALA A 1 982  ? 143.855 146.558 159.132 1.00 129.44 ? 1104 ALA A O   1 
ATOM   6818 C CB  . ALA A 1 982  ? 141.333 145.674 157.135 1.00 120.67 ? 1104 ALA A CB  1 
ATOM   6819 N N   . LEU A 1 983  ? 142.926 148.221 157.918 1.00 121.24 ? 1105 LEU A N   1 
ATOM   6820 C CA  . LEU A 1 983  ? 143.208 149.283 158.876 1.00 115.07 ? 1105 LEU A CA  1 
ATOM   6821 C C   . LEU A 1 983  ? 141.987 150.182 158.966 1.00 107.48 ? 1105 LEU A C   1 
ATOM   6822 O O   . LEU A 1 983  ? 141.725 150.967 158.051 1.00 114.50 ? 1105 LEU A O   1 
ATOM   6823 C CB  . LEU A 1 983  ? 144.440 150.090 158.460 1.00 117.81 ? 1105 LEU A CB  1 
ATOM   6824 C CG  . LEU A 1 983  ? 145.046 151.010 159.519 1.00 119.02 ? 1105 LEU A CG  1 
ATOM   6825 C CD1 . LEU A 1 983  ? 145.585 150.203 160.687 1.00 120.47 ? 1105 LEU A CD1 1 
ATOM   6826 C CD2 . LEU A 1 983  ? 146.139 151.870 158.909 1.00 106.42 ? 1105 LEU A CD2 1 
ATOM   6827 N N   . ARG A 1 984  ? 141.252 150.076 160.066 1.00 98.03  ? 1106 ARG A N   1 
ATOM   6828 C CA  . ARG A 1 984  ? 139.986 150.772 160.236 1.00 97.67  ? 1106 ARG A CA  1 
ATOM   6829 C C   . ARG A 1 984  ? 140.144 151.923 161.218 1.00 97.53  ? 1106 ARG A C   1 
ATOM   6830 O O   . ARG A 1 984  ? 140.975 151.866 162.127 1.00 103.92 ? 1106 ARG A O   1 
ATOM   6831 C CB  . ARG A 1 984  ? 138.908 149.808 160.727 1.00 103.87 ? 1106 ARG A CB  1 
ATOM   6832 C CG  . ARG A 1 984  ? 138.558 148.721 159.734 1.00 110.45 ? 1106 ARG A CG  1 
ATOM   6833 C CD  . ARG A 1 984  ? 137.408 147.868 160.234 1.00 109.68 ? 1106 ARG A CD  1 
ATOM   6834 N NE  . ARG A 1 984  ? 137.753 147.141 161.449 1.00 107.65 ? 1106 ARG A NE  1 
ATOM   6835 C CZ  . ARG A 1 984  ? 138.328 145.946 161.470 1.00 112.35 ? 1106 ARG A CZ  1 
ATOM   6836 N NH1 . ARG A 1 984  ? 138.652 145.314 160.353 1.00 118.07 ? 1106 ARG A NH1 1 
ATOM   6837 N NH2 . ARG A 1 984  ? 138.584 145.369 162.640 1.00 110.42 ? 1106 ARG A NH2 1 
ATOM   6838 N N   . LEU A 1 985  ? 139.344 152.968 161.025 1.00 92.55  ? 1107 LEU A N   1 
ATOM   6839 C CA  . LEU A 1 985  ? 139.380 154.175 161.838 1.00 86.21  ? 1107 LEU A CA  1 
ATOM   6840 C C   . LEU A 1 985  ? 137.971 154.487 162.318 1.00 86.62  ? 1107 LEU A C   1 
ATOM   6841 O O   . LEU A 1 985  ? 137.013 154.375 161.548 1.00 98.25  ? 1107 LEU A O   1 
ATOM   6842 C CB  . LEU A 1 985  ? 139.952 155.342 161.029 1.00 89.16  ? 1107 LEU A CB  1 
ATOM   6843 C CG  . LEU A 1 985  ? 140.016 156.748 161.618 1.00 90.69  ? 1107 LEU A CG  1 
ATOM   6844 C CD1 . LEU A 1 985  ? 140.975 156.800 162.793 1.00 91.60  ? 1107 LEU A CD1 1 
ATOM   6845 C CD2 . LEU A 1 985  ? 140.435 157.724 160.537 1.00 92.26  ? 1107 LEU A CD2 1 
ATOM   6846 N N   . TYR A 1 986  ? 137.834 154.875 163.584 1.00 79.09  ? 1108 TYR A N   1 
ATOM   6847 C CA  . TYR A 1 986  ? 136.517 154.999 164.193 1.00 79.32  ? 1108 TYR A CA  1 
ATOM   6848 C C   . TYR A 1 986  ? 136.371 156.351 164.886 1.00 77.38  ? 1108 TYR A C   1 
ATOM   6849 O O   . TYR A 1 986  ? 137.298 157.163 164.919 1.00 79.81  ? 1108 TYR A O   1 
ATOM   6850 C CB  . TYR A 1 986  ? 136.261 153.875 165.198 1.00 79.39  ? 1108 TYR A CB  1 
ATOM   6851 C CG  . TYR A 1 986  ? 136.072 152.492 164.619 1.00 87.55  ? 1108 TYR A CG  1 
ATOM   6852 C CD1 . TYR A 1 986  ? 137.177 151.683 164.327 1.00 87.06  ? 1108 TYR A CD1 1 
ATOM   6853 C CD2 . TYR A 1 986  ? 134.790 151.983 164.388 1.00 93.26  ? 1108 TYR A CD2 1 
ATOM   6854 C CE1 . TYR A 1 986  ? 137.010 150.406 163.803 1.00 92.84  ? 1108 TYR A CE1 1 
ATOM   6855 C CE2 . TYR A 1 986  ? 134.610 150.703 163.864 1.00 96.98  ? 1108 TYR A CE2 1 
ATOM   6856 C CZ  . TYR A 1 986  ? 135.727 149.928 163.574 1.00 98.98  ? 1108 TYR A CZ  1 
ATOM   6857 O OH  . TYR A 1 986  ? 135.566 148.665 163.056 1.00 97.84  ? 1108 TYR A OH  1 
ATOM   6858 N N   . ARG A 1 987  ? 135.185 156.578 165.455 1.00 76.94  ? 1109 ARG A N   1 
ATOM   6859 C CA  . ARG A 1 987  ? 134.854 157.836 166.124 1.00 74.50  ? 1109 ARG A CA  1 
ATOM   6860 C C   . ARG A 1 987  ? 133.772 157.560 167.158 1.00 83.89  ? 1109 ARG A C   1 
ATOM   6861 O O   . ARG A 1 987  ? 132.874 156.752 166.902 1.00 97.64  ? 1109 ARG A O   1 
ATOM   6862 C CB  . ARG A 1 987  ? 134.390 158.888 165.105 1.00 85.39  ? 1109 ARG A CB  1 
ATOM   6863 C CG  . ARG A 1 987  ? 134.222 160.312 165.641 1.00 93.37  ? 1109 ARG A CG  1 
ATOM   6864 C CD  . ARG A 1 987  ? 132.751 160.693 165.747 1.00 104.97 ? 1109 ARG A CD  1 
ATOM   6865 N NE  . ARG A 1 987  ? 132.533 161.950 166.451 1.00 106.23 ? 1109 ARG A NE  1 
ATOM   6866 C CZ  . ARG A 1 987  ? 131.363 162.323 166.950 1.00 108.46 ? 1109 ARG A CZ  1 
ATOM   6867 N NH1 . ARG A 1 987  ? 130.291 161.557 166.845 1.00 107.10 ? 1109 ARG A NH1 1 
ATOM   6868 N NH2 . ARG A 1 987  ? 131.265 163.494 167.574 1.00 104.57 ? 1109 ARG A NH2 1 
ATOM   6869 N N   . ALA A 1 988  ? 133.851 158.219 168.319 1.00 80.30  ? 1110 ALA A N   1 
ATOM   6870 C CA  . ALA A 1 988  ? 132.839 158.127 169.363 1.00 85.94  ? 1110 ALA A CA  1 
ATOM   6871 C C   . ALA A 1 988  ? 132.814 159.405 170.192 1.00 89.65  ? 1110 ALA A C   1 
ATOM   6872 O O   . ALA A 1 988  ? 133.851 160.056 170.345 1.00 100.58 ? 1110 ALA A O   1 
ATOM   6873 C CB  . ALA A 1 988  ? 133.104 156.930 170.284 1.00 86.47  ? 1110 ALA A CB  1 
ATOM   6874 N N   . PRO A 1 989  ? 131.662 159.792 170.740 1.00 86.80  ? 1111 PRO A N   1 
ATOM   6875 C CA  . PRO A 1 989  ? 131.633 160.924 171.671 1.00 92.11  ? 1111 PRO A CA  1 
ATOM   6876 C C   . PRO A 1 989  ? 132.090 160.537 173.071 1.00 93.38  ? 1111 PRO A C   1 
ATOM   6877 O O   . PRO A 1 989  ? 132.415 159.386 173.361 1.00 93.54  ? 1111 PRO A O   1 
ATOM   6878 C CB  . PRO A 1 989  ? 130.157 161.343 171.680 1.00 100.37 ? 1111 PRO A CB  1 
ATOM   6879 C CG  . PRO A 1 989  ? 129.570 160.725 170.465 1.00 106.24 ? 1111 PRO A CG  1 
ATOM   6880 C CD  . PRO A 1 989  ? 130.304 159.445 170.291 1.00 98.09  ? 1111 PRO A CD  1 
ATOM   6881 N N   . LEU A 1 990  ? 132.099 161.536 173.952 1.00 95.31  ? 1112 LEU A N   1 
ATOM   6882 C CA  . LEU A 1 990  ? 132.564 161.363 175.322 1.00 98.02  ? 1112 LEU A CA  1 
ATOM   6883 C C   . LEU A 1 990  ? 131.437 161.289 176.339 1.00 110.28 ? 1112 LEU A C   1 
ATOM   6884 O O   . LEU A 1 990  ? 131.692 161.485 177.532 1.00 113.98 ? 1112 LEU A O   1 
ATOM   6885 C CB  . LEU A 1 990  ? 133.509 162.498 175.724 1.00 94.96  ? 1112 LEU A CB  1 
ATOM   6886 C CG  . LEU A 1 990  ? 134.938 162.505 175.189 1.00 94.23  ? 1112 LEU A CG  1 
ATOM   6887 C CD1 . LEU A 1 990  ? 135.763 163.558 175.910 1.00 95.69  ? 1112 LEU A CD1 1 
ATOM   6888 C CD2 . LEU A 1 990  ? 135.572 161.151 175.293 1.00 87.31  ? 1112 LEU A CD2 1 
ATOM   6889 N N   . THR A 1 991  ? 130.206 161.043 175.903 1.00 114.54 ? 1113 THR A N   1 
ATOM   6890 C CA  . THR A 1 991  ? 129.107 160.889 176.845 1.00 122.50 ? 1113 THR A CA  1 
ATOM   6891 C C   . THR A 1 991  ? 129.186 159.530 177.530 1.00 131.63 ? 1113 THR A C   1 
ATOM   6892 O O   . THR A 1 991  ? 129.797 158.588 177.016 1.00 127.64 ? 1113 THR A O   1 
ATOM   6893 C CB  . THR A 1 991  ? 127.767 161.040 176.129 1.00 128.11 ? 1113 THR A CB  1 
ATOM   6894 O OG1 . THR A 1 991  ? 127.662 160.049 175.099 1.00 127.76 ? 1113 THR A OG1 1 
ATOM   6895 C CG2 . THR A 1 991  ? 127.655 162.422 175.506 1.00 129.93 ? 1113 THR A CG2 1 
ATOM   6896 N N   . ALA A 1 992  ? 128.591 159.450 178.727 1.00 137.00 ? 1114 ALA A N   1 
ATOM   6897 C CA  . ALA A 1 992  ? 128.534 158.184 179.453 1.00 134.91 ? 1114 ALA A CA  1 
ATOM   6898 C C   . ALA A 1 992  ? 127.567 157.213 178.788 1.00 140.92 ? 1114 ALA A C   1 
ATOM   6899 O O   . ALA A 1 992  ? 127.839 156.009 178.707 1.00 137.43 ? 1114 ALA A O   1 
ATOM   6900 C CB  . ALA A 1 992  ? 128.137 158.431 180.908 1.00 128.32 ? 1114 ALA A CB  1 
ATOM   6901 N N   . GLY A 1 993  ? 126.440 157.720 178.301 1.00 144.58 ? 1115 GLY A N   1 
ATOM   6902 C CA  . GLY A 1 993  ? 125.595 156.959 177.405 1.00 142.56 ? 1115 GLY A CA  1 
ATOM   6903 C C   . GLY A 1 993  ? 125.919 157.329 175.974 1.00 146.89 ? 1115 GLY A C   1 
ATOM   6904 O O   . GLY A 1 993  ? 125.624 158.449 175.544 1.00 146.05 ? 1115 GLY A O   1 
ATOM   6905 N N   . GLY A 1 994  ? 126.547 156.405 175.243 1.00 149.42 ? 1116 GLY A N   1 
ATOM   6906 C CA  . GLY A 1 994  ? 127.036 156.655 173.898 1.00 151.61 ? 1116 GLY A CA  1 
ATOM   6907 C C   . GLY A 1 994  ? 125.959 156.835 172.847 1.00 152.21 ? 1116 GLY A C   1 
ATOM   6908 O O   . GLY A 1 994  ? 125.073 155.988 172.702 1.00 148.74 ? 1116 GLY A O   1 
ATOM   6909 N N   . ASP A 1 995  ? 126.031 157.951 172.113 1.00 148.77 ? 1117 ASP A N   1 
ATOM   6910 C CA  . ASP A 1 995  ? 124.995 158.267 171.135 1.00 147.41 ? 1117 ASP A CA  1 
ATOM   6911 C C   . ASP A 1 995  ? 125.165 157.451 169.861 1.00 141.23 ? 1117 ASP A C   1 
ATOM   6912 O O   . ASP A 1 995  ? 124.212 156.815 169.397 1.00 140.69 ? 1117 ASP A O   1 
ATOM   6913 C CB  . ASP A 1 995  ? 125.014 159.762 170.821 1.00 143.89 ? 1117 ASP A CB  1 
ATOM   6914 C CG  . ASP A 1 995  ? 124.837 160.619 172.057 1.00 145.71 ? 1117 ASP A CG  1 
ATOM   6915 O OD1 . ASP A 1 995  ? 124.471 160.071 173.118 1.00 140.98 ? 1117 ASP A OD1 1 
ATOM   6916 O OD2 . ASP A 1 995  ? 125.063 161.843 171.968 1.00 152.20 ? 1117 ASP A OD2 1 
ATOM   6917 N N   . SER A 1 996  ? 126.372 157.437 169.297 1.00 131.49 ? 1118 SER A N   1 
ATOM   6918 C CA  . SER A 1 996  ? 126.627 156.726 168.053 1.00 130.43 ? 1118 SER A CA  1 
ATOM   6919 C C   . SER A 1 996  ? 128.098 156.348 167.989 1.00 121.73 ? 1118 SER A C   1 
ATOM   6920 O O   . SER A 1 996  ? 128.897 156.729 168.846 1.00 117.63 ? 1118 SER A O   1 
ATOM   6921 C CB  . SER A 1 996  ? 126.235 157.565 166.833 1.00 131.83 ? 1118 SER A CB  1 
ATOM   6922 O OG  . SER A 1 996  ? 127.010 158.749 166.756 1.00 125.86 ? 1118 SER A OG  1 
ATOM   6923 N N   . LEU A 1 997  ? 128.437 155.577 166.960 1.00 116.32 ? 1119 LEU A N   1 
ATOM   6924 C CA  . LEU A 1 997  ? 129.802 155.139 166.704 1.00 109.33 ? 1119 LEU A CA  1 
ATOM   6925 C C   . LEU A 1 997  ? 129.963 154.993 165.199 1.00 108.33 ? 1119 LEU A C   1 
ATOM   6926 O O   . LEU A 1 997  ? 129.295 154.158 164.580 1.00 112.93 ? 1119 LEU A O   1 
ATOM   6927 C CB  . LEU A 1 997  ? 130.092 153.824 167.447 1.00 107.10 ? 1119 LEU A CB  1 
ATOM   6928 C CG  . LEU A 1 997  ? 131.474 153.169 167.558 1.00 103.12 ? 1119 LEU A CG  1 
ATOM   6929 C CD1 . LEU A 1 997  ? 131.560 152.466 168.895 1.00 97.60  ? 1119 LEU A CD1 1 
ATOM   6930 C CD2 . LEU A 1 997  ? 131.732 152.148 166.462 1.00 97.30  ? 1119 LEU A CD2 1 
ATOM   6931 N N   . GLN A 1 998  ? 130.844 155.799 164.612 1.00 99.77  ? 1120 GLN A N   1 
ATOM   6932 C CA  . GLN A 1 998  ? 130.999 155.862 163.162 1.00 99.38  ? 1120 GLN A CA  1 
ATOM   6933 C C   . GLN A 1 998  ? 132.358 155.306 162.778 1.00 90.86  ? 1120 GLN A C   1 
ATOM   6934 O O   . GLN A 1 998  ? 133.383 155.819 163.230 1.00 98.61  ? 1120 GLN A O   1 
ATOM   6935 C CB  . GLN A 1 998  ? 130.871 157.298 162.643 1.00 103.12 ? 1120 GLN A CB  1 
ATOM   6936 C CG  . GLN A 1 998  ? 129.484 157.915 162.709 1.00 111.04 ? 1120 GLN A CG  1 
ATOM   6937 C CD  . GLN A 1 998  ? 129.196 158.576 164.040 1.00 119.71 ? 1120 GLN A CD  1 
ATOM   6938 O OE1 . GLN A 1 998  ? 130.083 158.717 164.881 1.00 115.45 ? 1120 GLN A OE1 1 
ATOM   6939 N NE2 . GLN A 1 998  ? 127.958 159.013 164.226 1.00 122.05 ? 1120 GLN A NE2 1 
ATOM   6940 N N   . MET A 1 999  ? 132.370 154.284 161.929 1.00 88.41  ? 1121 MET A N   1 
ATOM   6941 C CA  . MET A 1 999  ? 133.600 153.859 161.275 1.00 90.96  ? 1121 MET A CA  1 
ATOM   6942 C C   . MET A 1 999  ? 133.905 154.877 160.184 1.00 95.06  ? 1121 MET A C   1 
ATOM   6943 O O   . MET A 1 999  ? 133.101 155.069 159.267 1.00 103.64 ? 1121 MET A O   1 
ATOM   6944 C CB  . MET A 1 999  ? 133.445 152.440 160.717 1.00 92.17  ? 1121 MET A CB  1 
ATOM   6945 C CG  . MET A 1 999  ? 134.676 151.786 160.046 1.00 96.93  ? 1121 MET A CG  1 
ATOM   6946 S SD  . MET A 1 999  ? 135.095 152.149 158.320 1.00 123.47 ? 1121 MET A SD  1 
ATOM   6947 C CE  . MET A 1 999  ? 133.800 151.266 157.445 1.00 123.37 ? 1121 MET A CE  1 
ATOM   6948 N N   . ILE A 1 1000 ? 135.055 155.537 160.290 1.00 90.57  ? 1122 ILE A N   1 
ATOM   6949 C CA  . ILE A 1 1000 ? 135.351 156.663 159.410 1.00 93.47  ? 1122 ILE A CA  1 
ATOM   6950 C C   . ILE A 1 1000 ? 135.850 156.175 158.056 1.00 98.10  ? 1122 ILE A C   1 
ATOM   6951 O O   . ILE A 1 1000 ? 135.237 156.454 157.018 1.00 102.07 ? 1122 ILE A O   1 
ATOM   6952 C CB  . ILE A 1 1000 ? 136.359 157.617 160.075 1.00 92.03  ? 1122 ILE A CB  1 
ATOM   6953 C CG1 . ILE A 1 1000 ? 135.748 158.246 161.327 1.00 87.93  ? 1122 ILE A CG1 1 
ATOM   6954 C CG2 . ILE A 1 1000 ? 136.785 158.713 159.109 1.00 102.05 ? 1122 ILE A CG2 1 
ATOM   6955 C CD1 . ILE A 1 1000 ? 136.717 159.106 162.112 1.00 92.85  ? 1122 ILE A CD1 1 
ATOM   6956 N N   . GLN A 1 1001 ? 136.950 155.427 158.044 1.00 96.33  ? 1123 GLN A N   1 
ATOM   6957 C CA  . GLN A 1 1001 ? 137.581 155.060 156.787 1.00 103.94 ? 1123 GLN A CA  1 
ATOM   6958 C C   . GLN A 1 1001 ? 138.330 153.752 157.007 1.00 105.39 ? 1123 GLN A C   1 
ATOM   6959 O O   . GLN A 1 1001 ? 138.847 153.506 158.098 1.00 108.47 ? 1123 GLN A O   1 
ATOM   6960 C CB  . GLN A 1 1001 ? 138.510 156.196 156.308 1.00 102.77 ? 1123 GLN A CB  1 
ATOM   6961 C CG  . GLN A 1 1001 ? 139.108 156.091 154.898 1.00 107.11 ? 1123 GLN A CG  1 
ATOM   6962 C CD  . GLN A 1 1001 ? 140.387 155.294 154.809 1.00 118.93 ? 1123 GLN A CD  1 
ATOM   6963 O OE1 . GLN A 1 1001 ? 141.166 155.233 155.760 1.00 121.19 ? 1123 GLN A OE1 1 
ATOM   6964 N NE2 . GLN A 1 1001 ? 140.616 154.684 153.654 1.00 117.61 ? 1123 GLN A NE2 1 
ATOM   6965 N N   . GLN A 1 1002 ? 138.386 152.923 155.969 1.00 106.31 ? 1124 GLN A N   1 
ATOM   6966 C CA  . GLN A 1 1002 ? 139.075 151.642 156.009 1.00 108.89 ? 1124 GLN A CA  1 
ATOM   6967 C C   . GLN A 1 1002 ? 140.090 151.576 154.876 1.00 112.85 ? 1124 GLN A C   1 
ATOM   6968 O O   . GLN A 1 1002 ? 139.754 151.865 153.724 1.00 120.33 ? 1124 GLN A O   1 
ATOM   6969 C CB  . GLN A 1 1002 ? 138.074 150.490 155.896 1.00 112.95 ? 1124 GLN A CB  1 
ATOM   6970 C CG  . GLN A 1 1002 ? 138.685 149.102 155.941 1.00 118.88 ? 1124 GLN A CG  1 
ATOM   6971 C CD  . GLN A 1 1002 ? 137.645 148.024 156.155 1.00 126.56 ? 1124 GLN A CD  1 
ATOM   6972 O OE1 . GLN A 1 1002 ? 136.450 148.257 155.977 1.00 124.45 ? 1124 GLN A OE1 1 
ATOM   6973 N NE2 . GLN A 1 1002 ? 138.094 146.837 156.538 1.00 128.15 ? 1124 GLN A NE2 1 
ATOM   6974 N N   . ILE A 1 1003 ? 141.323 151.197 155.202 1.00 114.99 ? 1125 ILE A N   1 
ATOM   6975 C CA  . ILE A 1 1003 ? 142.358 150.921 154.211 1.00 121.72 ? 1125 ILE A CA  1 
ATOM   6976 C C   . ILE A 1 1003 ? 142.525 149.411 154.129 1.00 128.07 ? 1125 ILE A C   1 
ATOM   6977 O O   . ILE A 1 1003 ? 142.904 148.769 155.115 1.00 129.17 ? 1125 ILE A O   1 
ATOM   6978 C CB  . ILE A 1 1003 ? 143.693 151.597 154.561 1.00 122.17 ? 1125 ILE A CB  1 
ATOM   6979 C CG1 . ILE A 1 1003 ? 143.537 153.121 154.576 1.00 116.78 ? 1125 ILE A CG1 1 
ATOM   6980 C CG2 . ILE A 1 1003 ? 144.788 151.141 153.587 1.00 121.70 ? 1125 ILE A CG2 1 
ATOM   6981 C CD1 . ILE A 1 1003 ? 144.828 153.904 154.763 1.00 111.44 ? 1125 ILE A CD1 1 
ATOM   6982 N N   . LYS A 1 1004 ? 142.241 148.844 152.959 1.00 130.71 ? 1126 LYS A N   1 
ATOM   6983 C CA  . LYS A 1 1004 ? 142.412 147.411 152.730 1.00 134.31 ? 1126 LYS A CA  1 
ATOM   6984 C C   . LYS A 1 1004 ? 143.766 147.197 152.067 1.00 136.63 ? 1126 LYS A C   1 
ATOM   6985 O O   . LYS A 1 1004 ? 143.929 147.434 150.869 1.00 139.51 ? 1126 LYS A O   1 
ATOM   6986 C CB  . LYS A 1 1004 ? 141.276 146.858 151.879 1.00 132.56 ? 1126 LYS A CB  1 
ATOM   6987 C CG  . LYS A 1 1004 ? 139.988 146.625 152.647 1.00 132.50 ? 1126 LYS A CG  1 
ATOM   6988 C CD  . LYS A 1 1004 ? 139.956 145.232 153.250 1.00 133.24 ? 1126 LYS A CD  1 
ATOM   6989 C CE  . LYS A 1 1004 ? 138.552 144.847 153.682 1.00 134.08 ? 1126 LYS A CE  1 
ATOM   6990 N NZ  . LYS A 1 1004 ? 138.521 143.515 154.347 1.00 137.41 ? 1126 LYS A NZ  1 
ATOM   6991 N N   . GLY A 1 1005 ? 144.743 146.750 152.851 1.00 137.29 ? 1127 GLY A N   1 
ATOM   6992 C CA  . GLY A 1 1005 ? 146.075 146.527 152.325 1.00 139.29 ? 1127 GLY A CA  1 
ATOM   6993 C C   . GLY A 1 1005 ? 146.974 145.891 153.357 1.00 144.96 ? 1127 GLY A C   1 
ATOM   6994 O O   . GLY A 1 1005 ? 146.591 145.695 154.514 1.00 140.50 ? 1127 GLY A O   1 
ATOM   6995 N N   . VAL A 1 1006 ? 148.193 145.569 152.918 1.00 148.17 ? 1128 VAL A N   1 
ATOM   6996 C CA  . VAL A 1 1006 ? 149.167 144.950 153.812 1.00 151.20 ? 1128 VAL A CA  1 
ATOM   6997 C C   . VAL A 1 1006 ? 149.920 146.034 154.587 1.00 152.11 ? 1128 VAL A C   1 
ATOM   6998 O O   . VAL A 1 1006 ? 150.466 145.789 155.673 1.00 147.50 ? 1128 VAL A O   1 
ATOM   6999 C CB  . VAL A 1 1006 ? 150.096 144.016 152.995 1.00 151.55 ? 1128 VAL A CB  1 
ATOM   7000 C CG1 . VAL A 1 1006 ? 150.965 144.781 151.985 1.00 147.81 ? 1128 VAL A CG1 1 
ATOM   7001 C CG2 . VAL A 1 1006 ? 150.909 143.032 153.863 1.00 147.31 ? 1128 VAL A CG2 1 
ATOM   7002 N N   . PHE A 1 1007 ? 149.885 147.271 154.087 1.00 152.70 ? 1129 PHE A N   1 
ATOM   7003 C CA  . PHE A 1 1007 ? 150.546 148.377 154.767 1.00 143.22 ? 1129 PHE A CA  1 
ATOM   7004 C C   . PHE A 1 1007 ? 149.681 148.878 155.915 1.00 141.95 ? 1129 PHE A C   1 
ATOM   7005 O O   . PHE A 1 1007 ? 148.501 149.187 155.732 1.00 139.02 ? 1129 PHE A O   1 
ATOM   7006 C CB  . PHE A 1 1007 ? 150.823 149.509 153.780 1.00 128.88 ? 1129 PHE A CB  1 
ATOM   7007 N N   . GLN A 1 1008 ? 150.274 148.957 157.104 1.00 134.46 ? 1130 GLN A N   1 
ATOM   7008 C CA  . GLN A 1 1008 ? 149.541 149.324 158.304 1.00 130.86 ? 1130 GLN A CA  1 
ATOM   7009 C C   . GLN A 1 1008 ? 150.324 150.374 159.075 1.00 119.36 ? 1130 GLN A C   1 
ATOM   7010 O O   . GLN A 1 1008 ? 151.401 150.809 158.661 1.00 113.44 ? 1130 GLN A O   1 
ATOM   7011 C CB  . GLN A 1 1008 ? 149.274 148.106 159.188 1.00 132.59 ? 1130 GLN A CB  1 
ATOM   7012 C CG  . GLN A 1 1008 ? 148.007 147.364 158.833 1.00 134.64 ? 1130 GLN A CG  1 
ATOM   7013 C CD  . GLN A 1 1008 ? 148.049 145.916 159.265 1.00 139.08 ? 1130 GLN A CD  1 
ATOM   7014 O OE1 . GLN A 1 1008 ? 149.087 145.414 159.702 1.00 139.61 ? 1130 GLN A OE1 1 
ATOM   7015 N NE2 . GLN A 1 1008 ? 146.921 145.231 159.141 1.00 133.24 ? 1130 GLN A NE2 1 
ATOM   7016 N N   . ALA A 1 1009 ? 149.772 150.764 160.217 1.00 115.16 ? 1131 ALA A N   1 
ATOM   7017 C CA  . ALA A 1 1009 ? 150.296 151.884 160.978 1.00 105.10 ? 1131 ALA A CA  1 
ATOM   7018 C C   . ALA A 1 1009 ? 151.329 151.438 162.004 1.00 102.30 ? 1131 ALA A C   1 
ATOM   7019 O O   . ALA A 1 1009 ? 151.336 150.290 162.457 1.00 104.74 ? 1131 ALA A O   1 
ATOM   7020 C CB  . ALA A 1 1009 ? 149.160 152.612 161.691 1.00 101.90 ? 1131 ALA A CB  1 
ATOM   7021 N N   . VAL A 1 1010 ? 152.215 152.362 162.350 1.00 94.21  ? 1132 VAL A N   1 
ATOM   7022 C CA  . VAL A 1 1010 ? 153.017 152.243 163.573 1.00 91.28  ? 1132 VAL A CA  1 
ATOM   7023 C C   . VAL A 1 1010 ? 152.081 152.365 164.772 1.00 94.18  ? 1132 VAL A C   1 
ATOM   7024 O O   . VAL A 1 1010 ? 151.169 153.212 164.745 1.00 97.74  ? 1132 VAL A O   1 
ATOM   7025 C CB  . VAL A 1 1010 ? 154.109 153.327 163.593 1.00 88.19  ? 1132 VAL A CB  1 
ATOM   7026 C CG1 . VAL A 1 1010 ? 154.923 153.321 164.881 1.00 91.23  ? 1132 VAL A CG1 1 
ATOM   7027 C CG2 . VAL A 1 1010 ? 155.038 153.141 162.429 1.00 89.44  ? 1132 VAL A CG2 1 
ATOM   7028 N N   . PRO A 1 1011 ? 152.185 151.495 165.782 1.00 93.39  ? 1133 PRO A N   1 
ATOM   7029 C CA  . PRO A 1 1011 ? 151.407 151.695 167.010 1.00 89.53  ? 1133 PRO A CA  1 
ATOM   7030 C C   . PRO A 1 1011 ? 151.883 152.907 167.796 1.00 91.16  ? 1133 PRO A C   1 
ATOM   7031 O O   . PRO A 1 1011 ? 153.080 153.212 167.828 1.00 94.36  ? 1133 PRO A O   1 
ATOM   7032 C CB  . PRO A 1 1011 ? 151.645 150.400 167.796 1.00 90.48  ? 1133 PRO A CB  1 
ATOM   7033 C CG  . PRO A 1 1011 ? 152.130 149.417 166.786 1.00 98.01  ? 1133 PRO A CG  1 
ATOM   7034 C CD  . PRO A 1 1011 ? 152.914 150.218 165.806 1.00 96.09  ? 1133 PRO A CD  1 
ATOM   7035 N N   . ASP A 1 1012 ? 150.902 153.565 168.445 1.00 88.09  ? 1134 ASP A N   1 
ATOM   7036 C CA  . ASP A 1 1012 ? 151.010 154.871 169.126 1.00 85.99  ? 1134 ASP A CA  1 
ATOM   7037 C C   . ASP A 1 1012 ? 151.588 155.946 168.202 1.00 83.80  ? 1134 ASP A C   1 
ATOM   7038 O O   . ASP A 1 1012 ? 152.521 156.669 168.555 1.00 91.48  ? 1134 ASP A O   1 
ATOM   7039 C CB  . ASP A 1 1012 ? 151.793 154.769 170.445 1.00 92.37  ? 1134 ASP A CB  1 
ATOM   7040 C CG  . ASP A 1 1012 ? 151.449 155.881 171.425 1.00 97.52  ? 1134 ASP A CG  1 
ATOM   7041 O OD1 . ASP A 1 1012 ? 150.357 155.837 172.025 1.00 94.97  ? 1134 ASP A OD1 1 
ATOM   7042 O OD2 . ASP A 1 1012 ? 152.281 156.795 171.598 1.00 101.38 ? 1134 ASP A OD2 1 
ATOM   7043 N N   . SER A 1 1013 ? 151.043 156.032 166.992 1.00 78.06  ? 1135 SER A N   1 
ATOM   7044 C CA  . SER A 1 1013 ? 151.459 157.043 166.033 1.00 80.39  ? 1135 SER A CA  1 
ATOM   7045 C C   . SER A 1 1013 ? 150.303 157.856 165.482 1.00 79.58  ? 1135 SER A C   1 
ATOM   7046 O O   . SER A 1 1013 ? 150.531 158.711 164.620 1.00 81.13  ? 1135 SER A O   1 
ATOM   7047 C CB  . SER A 1 1013 ? 152.222 156.405 164.868 1.00 81.89  ? 1135 SER A CB  1 
ATOM   7048 O OG  . SER A 1 1013 ? 151.334 155.714 164.010 1.00 88.07  ? 1135 SER A OG  1 
ATOM   7049 N N   . LEU A 1 1014 ? 149.076 157.611 165.934 1.00 77.94  ? 1136 LEU A N   1 
ATOM   7050 C CA  . LEU A 1 1014 ? 147.943 158.426 165.522 1.00 72.75  ? 1136 LEU A CA  1 
ATOM   7051 C C   . LEU A 1 1014 ? 148.001 159.759 166.249 1.00 72.06  ? 1136 LEU A C   1 
ATOM   7052 O O   . LEU A 1 1014 ? 148.148 159.800 167.474 1.00 75.72  ? 1136 LEU A O   1 
ATOM   7053 C CB  . LEU A 1 1014 ? 146.624 157.711 165.801 1.00 74.60  ? 1136 LEU A CB  1 
ATOM   7054 C CG  . LEU A 1 1014 ? 145.344 158.353 165.268 1.00 71.86  ? 1136 LEU A CG  1 
ATOM   7055 C CD1 . LEU A 1 1014 ? 145.271 158.252 163.761 1.00 74.49  ? 1136 LEU A CD1 1 
ATOM   7056 C CD2 . LEU A 1 1014 ? 144.138 157.698 165.903 1.00 75.15  ? 1136 LEU A CD2 1 
ATOM   7057 N N   . GLN A 1 1015 ? 147.912 160.844 165.492 1.00 69.52  ? 1137 GLN A N   1 
ATOM   7058 C CA  . GLN A 1 1015 ? 147.928 162.190 166.035 1.00 69.47  ? 1137 GLN A CA  1 
ATOM   7059 C C   . GLN A 1 1015 ? 146.717 162.932 165.495 1.00 69.84  ? 1137 GLN A C   1 
ATOM   7060 O O   . GLN A 1 1015 ? 146.210 162.612 164.420 1.00 74.95  ? 1137 GLN A O   1 
ATOM   7061 C CB  . GLN A 1 1015 ? 149.210 162.945 165.649 1.00 74.58  ? 1137 GLN A CB  1 
ATOM   7062 C CG  . GLN A 1 1015 ? 150.512 162.373 166.205 1.00 73.65  ? 1137 GLN A CG  1 
ATOM   7063 C CD  . GLN A 1 1015 ? 150.593 162.425 167.714 1.00 84.23  ? 1137 GLN A CD  1 
ATOM   7064 O OE1 . GLN A 1 1015 ? 150.551 161.395 168.386 1.00 88.69  ? 1137 GLN A OE1 1 
ATOM   7065 N NE2 . GLN A 1 1015 ? 150.696 163.631 168.258 1.00 81.66  ? 1137 GLN A NE2 1 
ATOM   7066 N N   . LEU A 1 1016 ? 146.250 163.923 166.246 1.00 67.83  ? 1138 LEU A N   1 
ATOM   7067 C CA  . LEU A 1 1016 ? 145.146 164.764 165.800 1.00 70.58  ? 1138 LEU A CA  1 
ATOM   7068 C C   . LEU A 1 1016 ? 145.704 166.099 165.338 1.00 74.55  ? 1138 LEU A C   1 
ATOM   7069 O O   . LEU A 1 1016 ? 146.436 166.766 166.075 1.00 76.23  ? 1138 LEU A O   1 
ATOM   7070 C CB  . LEU A 1 1016 ? 144.121 164.967 166.907 1.00 70.05  ? 1138 LEU A CB  1 
ATOM   7071 C CG  . LEU A 1 1016 ? 142.880 165.804 166.607 1.00 75.11  ? 1138 LEU A CG  1 
ATOM   7072 C CD1 . LEU A 1 1016 ? 141.948 165.073 165.661 1.00 71.72  ? 1138 LEU A CD1 1 
ATOM   7073 C CD2 . LEU A 1 1016 ? 142.161 166.125 167.900 1.00 81.73  ? 1138 LEU A CD2 1 
ATOM   7074 N N   . LEU A 1 1017 ? 145.352 166.491 164.119 1.00 70.37  ? 1139 LEU A N   1 
ATOM   7075 C CA  . LEU A 1 1017 ? 145.712 167.800 163.591 1.00 71.07  ? 1139 LEU A CA  1 
ATOM   7076 C C   . LEU A 1 1017 ? 144.517 168.708 163.839 1.00 77.56  ? 1139 LEU A C   1 
ATOM   7077 O O   . LEU A 1 1017 ? 143.603 168.803 163.024 1.00 87.41  ? 1139 LEU A O   1 
ATOM   7078 C CB  . LEU A 1 1017 ? 146.074 167.707 162.117 1.00 69.32  ? 1139 LEU A CB  1 
ATOM   7079 C CG  . LEU A 1 1017 ? 147.012 166.558 161.745 1.00 70.88  ? 1139 LEU A CG  1 
ATOM   7080 C CD1 . LEU A 1 1017 ? 147.176 166.478 160.245 1.00 75.49  ? 1139 LEU A CD1 1 
ATOM   7081 C CD2 . LEU A 1 1017 ? 148.363 166.705 162.413 1.00 69.17  ? 1139 LEU A CD2 1 
ATOM   7082 N N   . ARG A 1 1018 ? 144.516 169.346 165.008 1.00 70.51  ? 1140 ARG A N   1 
ATOM   7083 C CA  . ARG A 1 1018 ? 143.458 170.293 165.361 1.00 73.34  ? 1140 ARG A CA  1 
ATOM   7084 C C   . ARG A 1 1018 ? 143.366 171.580 164.525 1.00 85.99  ? 1140 ARG A C   1 
ATOM   7085 O O   . ARG A 1 1018 ? 142.262 172.153 164.497 1.00 90.59  ? 1140 ARG A O   1 
ATOM   7086 C CB  . ARG A 1 1018 ? 143.573 170.654 166.849 1.00 76.46  ? 1140 ARG A CB  1 
ATOM   7087 C CG  . ARG A 1 1018 ? 142.673 169.885 167.772 1.00 88.10  ? 1140 ARG A CG  1 
ATOM   7088 C CD  . ARG A 1 1018 ? 143.223 169.984 169.173 1.00 94.38  ? 1140 ARG A CD  1 
ATOM   7089 N NE  . ARG A 1 1018 ? 142.396 169.312 170.164 1.00 100.66 ? 1140 ARG A NE  1 
ATOM   7090 C CZ  . ARG A 1 1018 ? 142.733 169.181 171.438 1.00 109.13 ? 1140 ARG A CZ  1 
ATOM   7091 N NH1 . ARG A 1 1018 ? 143.873 169.663 171.903 1.00 113.67 ? 1140 ARG A NH1 1 
ATOM   7092 N NH2 . ARG A 1 1018 ? 141.911 168.544 172.264 1.00 103.41 ? 1140 ARG A NH2 1 
ATOM   7093 N N   . PRO A 1 1019 ? 144.430 172.134 163.889 1.00 84.32  ? 1141 PRO A N   1 
ATOM   7094 C CA  . PRO A 1 1019 ? 144.148 173.145 162.851 1.00 79.99  ? 1141 PRO A CA  1 
ATOM   7095 C C   . PRO A 1 1019 ? 143.456 172.613 161.607 1.00 83.54  ? 1141 PRO A C   1 
ATOM   7096 O O   . PRO A 1 1019 ? 142.477 173.222 161.162 1.00 86.65  ? 1141 PRO A O   1 
ATOM   7097 C CB  . PRO A 1 1019 ? 145.536 173.695 162.525 1.00 80.90  ? 1141 PRO A CB  1 
ATOM   7098 C CG  . PRO A 1 1019 ? 146.212 173.651 163.786 1.00 77.23  ? 1141 PRO A CG  1 
ATOM   7099 C CD  . PRO A 1 1019 ? 145.790 172.385 164.429 1.00 79.54  ? 1141 PRO A CD  1 
ATOM   7100 N N   . LEU A 1 1020 ? 143.930 171.514 161.026 1.00 78.13  ? 1142 LEU A N   1 
ATOM   7101 C CA  . LEU A 1 1020 ? 143.330 170.967 159.815 1.00 74.87  ? 1142 LEU A CA  1 
ATOM   7102 C C   . LEU A 1 1020 ? 141.986 170.293 160.074 1.00 82.98  ? 1142 LEU A C   1 
ATOM   7103 O O   . LEU A 1 1020 ? 141.112 170.325 159.202 1.00 92.53  ? 1142 LEU A O   1 
ATOM   7104 C CB  . LEU A 1 1020 ? 144.293 169.973 159.152 1.00 73.11  ? 1142 LEU A CB  1 
ATOM   7105 C CG  . LEU A 1 1020 ? 144.036 169.576 157.693 1.00 72.40  ? 1142 LEU A CG  1 
ATOM   7106 C CD1 . LEU A 1 1020 ? 143.936 170.807 156.811 1.00 78.00  ? 1142 LEU A CD1 1 
ATOM   7107 C CD2 . LEU A 1 1020 ? 145.101 168.632 157.172 1.00 73.92  ? 1142 LEU A CD2 1 
ATOM   7108 N N   . GLY A 1 1021 ? 141.777 169.747 161.267 1.00 76.77  ? 1143 GLY A N   1 
ATOM   7109 C CA  . GLY A 1 1021 ? 140.609 168.929 161.507 1.00 73.32  ? 1143 GLY A CA  1 
ATOM   7110 C C   . GLY A 1 1021 ? 140.829 167.584 160.860 1.00 77.65  ? 1143 GLY A C   1 
ATOM   7111 O O   . GLY A 1 1021 ? 140.015 167.129 160.052 1.00 86.93  ? 1143 GLY A O   1 
ATOM   7112 N N   . ALA A 1 1022 ? 141.947 166.947 161.193 1.00 66.69  ? 1144 ALA A N   1 
ATOM   7113 C CA  . ALA A 1 1022 ? 142.372 165.740 160.511 1.00 70.45  ? 1144 ALA A CA  1 
ATOM   7114 C C   . ALA A 1 1022 ? 143.113 164.830 161.476 1.00 69.24  ? 1144 ALA A C   1 
ATOM   7115 O O   . ALA A 1 1022 ? 143.530 165.242 162.559 1.00 76.54  ? 1144 ALA A O   1 
ATOM   7116 C CB  . ALA A 1 1022 ? 143.268 166.056 159.311 1.00 75.01  ? 1144 ALA A CB  1 
ATOM   7117 N N   . LEU A 1 1023 ? 143.262 163.578 161.064 1.00 66.20  ? 1145 LEU A N   1 
ATOM   7118 C CA  . LEU A 1 1023 ? 144.012 162.576 161.799 1.00 65.37  ? 1145 LEU A CA  1 
ATOM   7119 C C   . LEU A 1 1023 ? 145.216 162.144 160.980 1.00 69.37  ? 1145 LEU A C   1 
ATOM   7120 O O   . LEU A 1 1023 ? 145.137 162.012 159.758 1.00 83.56  ? 1145 LEU A O   1 
ATOM   7121 C CB  . LEU A 1 1023 ? 143.140 161.366 162.117 1.00 69.10  ? 1145 LEU A CB  1 
ATOM   7122 C CG  . LEU A 1 1023 ? 142.065 161.610 163.166 1.00 71.79  ? 1145 LEU A CG  1 
ATOM   7123 C CD1 . LEU A 1 1023 ? 140.945 160.629 162.960 1.00 75.86  ? 1145 LEU A CD1 1 
ATOM   7124 C CD2 . LEU A 1 1023 ? 142.648 161.466 164.555 1.00 71.61  ? 1145 LEU A CD2 1 
ATOM   7125 N N   . LEU A 1 1024 ? 146.331 161.916 161.660 1.00 64.67  ? 1146 LEU A N   1 
ATOM   7126 C CA  . LEU A 1 1024 ? 147.595 161.638 161.001 1.00 70.59  ? 1146 LEU A CA  1 
ATOM   7127 C C   . LEU A 1 1024 ? 148.283 160.466 161.677 1.00 76.02  ? 1146 LEU A C   1 
ATOM   7128 O O   . LEU A 1 1024 ? 148.483 160.478 162.892 1.00 82.10  ? 1146 LEU A O   1 
ATOM   7129 C CB  . LEU A 1 1024 ? 148.500 162.869 161.036 1.00 74.65  ? 1146 LEU A CB  1 
ATOM   7130 C CG  . LEU A 1 1024 ? 149.998 162.692 160.800 1.00 78.17  ? 1146 LEU A CG  1 
ATOM   7131 C CD1 . LEU A 1 1024 ? 150.280 162.420 159.338 1.00 81.20  ? 1146 LEU A CD1 1 
ATOM   7132 C CD2 . LEU A 1 1024 ? 150.737 163.924 161.280 1.00 79.27  ? 1146 LEU A CD2 1 
ATOM   7133 N N   . TRP A 1 1025 ? 148.646 159.458 160.889 1.00 76.96  ? 1147 TRP A N   1 
ATOM   7134 C CA  . TRP A 1 1025 ? 149.426 158.341 161.396 1.00 76.00  ? 1147 TRP A CA  1 
ATOM   7135 C C   . TRP A 1 1025 ? 150.584 158.060 160.453 1.00 78.98  ? 1147 TRP A C   1 
ATOM   7136 O O   . TRP A 1 1025 ? 150.568 158.454 159.285 1.00 88.55  ? 1147 TRP A O   1 
ATOM   7137 C CB  . TRP A 1 1025 ? 148.568 157.079 161.606 1.00 76.56  ? 1147 TRP A CB  1 
ATOM   7138 C CG  . TRP A 1 1025 ? 148.004 156.429 160.369 1.00 83.86  ? 1147 TRP A CG  1 
ATOM   7139 C CD1 . TRP A 1 1025 ? 148.596 155.475 159.588 1.00 89.68  ? 1147 TRP A CD1 1 
ATOM   7140 C CD2 . TRP A 1 1025 ? 146.713 156.661 159.800 1.00 85.40  ? 1147 TRP A CD2 1 
ATOM   7141 N NE1 . TRP A 1 1025 ? 147.764 155.116 158.562 1.00 92.64  ? 1147 TRP A NE1 1 
ATOM   7142 C CE2 . TRP A 1 1025 ? 146.600 155.827 158.669 1.00 90.73  ? 1147 TRP A CE2 1 
ATOM   7143 C CE3 . TRP A 1 1025 ? 145.643 157.501 160.132 1.00 82.14  ? 1147 TRP A CE3 1 
ATOM   7144 C CZ2 . TRP A 1 1025 ? 145.462 155.810 157.869 1.00 96.64  ? 1147 TRP A CZ2 1 
ATOM   7145 C CZ3 . TRP A 1 1025 ? 144.513 157.482 159.336 1.00 89.65  ? 1147 TRP A CZ3 1 
ATOM   7146 C CH2 . TRP A 1 1025 ? 144.433 156.639 158.219 1.00 97.96  ? 1147 TRP A CH2 1 
ATOM   7147 N N   . LEU A 1 1026 ? 151.589 157.372 160.979 1.00 76.19  ? 1148 LEU A N   1 
ATOM   7148 C CA  . LEU A 1 1026 ? 152.780 156.999 160.232 1.00 73.53  ? 1148 LEU A CA  1 
ATOM   7149 C C   . LEU A 1 1026 ? 152.693 155.522 159.871 1.00 89.87  ? 1148 LEU A C   1 
ATOM   7150 O O   . LEU A 1 1026 ? 152.308 154.699 160.708 1.00 96.43  ? 1148 LEU A O   1 
ATOM   7151 C CB  . LEU A 1 1026 ? 154.032 157.280 161.061 1.00 76.01  ? 1148 LEU A CB  1 
ATOM   7152 C CG  . LEU A 1 1026 ? 155.395 157.307 160.377 1.00 85.03  ? 1148 LEU A CG  1 
ATOM   7153 C CD1 . LEU A 1 1026 ? 155.538 158.534 159.503 1.00 85.17  ? 1148 LEU A CD1 1 
ATOM   7154 C CD2 . LEU A 1 1026 ? 156.484 157.274 161.424 1.00 81.08  ? 1148 LEU A CD2 1 
ATOM   7155 N N   . GLU A 1 1027 ? 153.029 155.191 158.626 1.00 91.84  ? 1149 GLU A N   1 
ATOM   7156 C CA  . GLU A 1 1027 ? 152.949 153.809 158.175 1.00 99.53  ? 1149 GLU A CA  1 
ATOM   7157 C C   . GLU A 1 1027 ? 154.141 153.003 158.681 1.00 104.19 ? 1149 GLU A C   1 
ATOM   7158 O O   . GLU A 1 1027 ? 155.161 153.562 159.094 1.00 104.52 ? 1149 GLU A O   1 
ATOM   7159 C CB  . GLU A 1 1027 ? 152.879 153.744 156.652 1.00 105.45 ? 1149 GLU A CB  1 
ATOM   7160 C CG  . GLU A 1 1027 ? 151.514 154.079 156.102 1.00 108.88 ? 1149 GLU A CG  1 
ATOM   7161 C CD  . GLU A 1 1027 ? 151.134 153.215 154.922 1.00 123.06 ? 1149 GLU A CD  1 
ATOM   7162 O OE1 . GLU A 1 1027 ? 152.043 152.645 154.285 1.00 125.24 ? 1149 GLU A OE1 1 
ATOM   7163 O OE2 . GLU A 1 1027 ? 149.925 153.104 154.633 1.00 123.85 ? 1149 GLU A OE2 1 
ATOM   7164 N N   . ARG A 1 1028 ? 154.007 151.666 158.609 1.00 108.63 ? 1150 ARG A N   1 
ATOM   7165 C CA  . ARG A 1 1028 ? 154.946 150.757 159.272 1.00 106.61 ? 1150 ARG A CA  1 
ATOM   7166 C C   . ARG A 1 1028 ? 156.287 150.677 158.554 1.00 105.66 ? 1150 ARG A C   1 
ATOM   7167 O O   . ARG A 1 1028 ? 157.295 150.300 159.164 1.00 106.52 ? 1150 ARG A O   1 
ATOM   7168 C CB  . ARG A 1 1028 ? 154.367 149.343 159.367 1.00 113.88 ? 1150 ARG A CB  1 
ATOM   7169 C CG  . ARG A 1 1028 ? 154.783 148.604 160.640 1.00 113.31 ? 1150 ARG A CG  1 
ATOM   7170 C CD  . ARG A 1 1028 ? 154.361 147.118 160.765 1.00 127.77 ? 1150 ARG A CD  1 
ATOM   7171 N NE  . ARG A 1 1028 ? 153.081 146.722 160.181 1.00 137.82 ? 1150 ARG A NE  1 
ATOM   7172 C CZ  . ARG A 1 1028 ? 152.949 146.101 159.015 1.00 140.41 ? 1150 ARG A CZ  1 
ATOM   7173 N NH1 . ARG A 1 1028 ? 154.000 145.800 158.270 1.00 142.16 ? 1150 ARG A NH1 1 
ATOM   7174 N NH2 . ARG A 1 1028 ? 151.734 145.769 158.589 1.00 136.32 ? 1150 ARG A NH2 1 
ATOM   7175 N N   . SER A 1 1029 ? 156.319 151.021 157.264 1.00 107.49 ? 1151 SER A N   1 
ATOM   7176 C CA  . SER A 1 1029 ? 157.584 151.081 156.539 1.00 110.80 ? 1151 SER A CA  1 
ATOM   7177 C C   . SER A 1 1029 ? 158.401 152.298 156.956 1.00 108.73 ? 1151 SER A C   1 
ATOM   7178 O O   . SER A 1 1029 ? 159.635 152.284 156.881 1.00 108.06 ? 1151 SER A O   1 
ATOM   7179 C CB  . SER A 1 1029 ? 157.322 151.100 155.035 1.00 111.42 ? 1151 SER A CB  1 
ATOM   7180 O OG  . SER A 1 1029 ? 156.512 152.205 154.677 1.00 108.63 ? 1151 SER A OG  1 
ATOM   7181 N N   . GLY A 1 1030 ? 157.730 153.352 157.409 1.00 106.41 ? 1152 GLY A N   1 
ATOM   7182 C CA  . GLY A 1 1030 ? 158.399 154.541 157.881 1.00 103.53 ? 1152 GLY A CA  1 
ATOM   7183 C C   . GLY A 1 1030 ? 158.788 155.526 156.812 1.00 103.34 ? 1152 GLY A C   1 
ATOM   7184 O O   . GLY A 1 1030 ? 159.452 156.520 157.123 1.00 101.12 ? 1152 GLY A O   1 
ATOM   7185 N N   . ARG A 1 1031 ? 158.390 155.290 155.564 1.00 108.33 ? 1153 ARG A N   1 
ATOM   7186 C CA  . ARG A 1 1031 ? 158.740 156.166 154.461 1.00 107.66 ? 1153 ARG A CA  1 
ATOM   7187 C C   . ARG A 1 1031 ? 157.559 156.968 153.939 1.00 106.04 ? 1153 ARG A C   1 
ATOM   7188 O O   . ARG A 1 1031 ? 157.729 157.736 152.984 1.00 105.23 ? 1153 ARG A O   1 
ATOM   7189 C CB  . ARG A 1 1031 ? 159.368 155.349 153.327 1.00 106.18 ? 1153 ARG A CB  1 
ATOM   7190 C CG  . ARG A 1 1031 ? 160.629 154.626 153.766 1.00 107.79 ? 1153 ARG A CG  1 
ATOM   7191 C CD  . ARG A 1 1031 ? 161.290 153.867 152.639 1.00 113.08 ? 1153 ARG A CD  1 
ATOM   7192 N NE  . ARG A 1 1031 ? 162.448 153.120 153.116 1.00 123.57 ? 1153 ARG A NE  1 
ATOM   7193 C CZ  . ARG A 1 1031 ? 163.676 153.614 153.198 1.00 122.02 ? 1153 ARG A CZ  1 
ATOM   7194 N NH1 . ARG A 1 1031 ? 163.951 154.851 152.821 1.00 115.75 ? 1153 ARG A NH1 1 
ATOM   7195 N NH2 . ARG A 1 1031 ? 164.654 152.845 153.669 1.00 115.59 ? 1153 ARG A NH2 1 
ATOM   7196 N N   . ARG A 1 1032 ? 156.386 156.839 154.555 1.00 100.31 ? 1154 ARG A N   1 
ATOM   7197 C CA  . ARG A 1 1032 ? 155.217 157.631 154.199 1.00 97.51  ? 1154 ARG A CA  1 
ATOM   7198 C C   . ARG A 1 1032 ? 154.320 157.759 155.420 1.00 99.51  ? 1154 ARG A C   1 
ATOM   7199 O O   . ARG A 1 1032 ? 154.443 157.004 156.387 1.00 102.67 ? 1154 ARG A O   1 
ATOM   7200 C CB  . ARG A 1 1032 ? 154.454 157.021 153.016 1.00 100.86 ? 1154 ARG A CB  1 
ATOM   7201 C CG  . ARG A 1 1032 ? 153.617 155.804 153.349 1.00 107.68 ? 1154 ARG A CG  1 
ATOM   7202 C CD  . ARG A 1 1032 ? 153.691 154.784 152.229 1.00 109.60 ? 1154 ARG A CD  1 
ATOM   7203 N NE  . ARG A 1 1032 ? 152.956 155.217 151.048 1.00 111.33 ? 1154 ARG A NE  1 
ATOM   7204 C CZ  . ARG A 1 1032 ? 151.679 154.944 150.823 1.00 115.05 ? 1154 ARG A CZ  1 
ATOM   7205 N NH1 . ARG A 1 1032 ? 150.965 154.233 151.676 1.00 106.81 ? 1154 ARG A NH1 1 
ATOM   7206 N NH2 . ARG A 1 1032 ? 151.107 155.394 149.709 1.00 117.40 ? 1154 ARG A NH2 1 
ATOM   7207 N N   . ALA A 1 1033 ? 153.424 158.741 155.365 1.00 94.27  ? 1155 ALA A N   1 
ATOM   7208 C CA  . ALA A 1 1033 ? 152.435 158.983 156.402 1.00 86.41  ? 1155 ALA A CA  1 
ATOM   7209 C C   . ALA A 1 1033 ? 151.095 159.273 155.748 1.00 89.04  ? 1155 ALA A C   1 
ATOM   7210 O O   . ALA A 1 1033 ? 151.037 159.770 154.622 1.00 100.25 ? 1155 ALA A O   1 
ATOM   7211 C CB  . ALA A 1 1033 ? 152.832 160.149 157.296 1.00 81.09  ? 1155 ALA A CB  1 
ATOM   7212 N N   . ARG A 1 1034 ? 150.014 158.958 156.456 1.00 79.74  ? 1156 ARG A N   1 
ATOM   7213 C CA  . ARG A 1 1034 ? 148.670 159.080 155.908 1.00 86.06  ? 1156 ARG A CA  1 
ATOM   7214 C C   . ARG A 1 1034 ? 147.878 160.118 156.688 1.00 84.79  ? 1156 ARG A C   1 
ATOM   7215 O O   . ARG A 1 1034 ? 147.954 160.169 157.918 1.00 88.99  ? 1156 ARG A O   1 
ATOM   7216 C CB  . ARG A 1 1034 ? 147.931 157.742 155.926 1.00 95.02  ? 1156 ARG A CB  1 
ATOM   7217 C CG  . ARG A 1 1034 ? 148.754 156.563 155.442 1.00 104.73 ? 1156 ARG A CG  1 
ATOM   7218 C CD  . ARG A 1 1034 ? 149.156 156.702 153.982 1.00 107.85 ? 1156 ARG A CD  1 
ATOM   7219 N NE  . ARG A 1 1034 ? 148.010 156.726 153.084 1.00 112.19 ? 1156 ARG A NE  1 
ATOM   7220 C CZ  . ARG A 1 1034 ? 147.499 155.651 152.501 1.00 118.75 ? 1156 ARG A CZ  1 
ATOM   7221 N NH1 . ARG A 1 1034 ? 147.997 154.446 152.718 1.00 116.61 ? 1156 ARG A NH1 1 
ATOM   7222 N NH2 . ARG A 1 1034 ? 146.463 155.788 151.680 1.00 120.39 ? 1156 ARG A NH2 1 
ATOM   7223 N N   . LEU A 1 1035 ? 147.121 160.936 155.966 1.00 85.93  ? 1157 LEU A N   1 
ATOM   7224 C CA  . LEU A 1 1035 ? 146.275 161.972 156.541 1.00 78.75  ? 1157 LEU A CA  1 
ATOM   7225 C C   . LEU A 1 1035 ? 144.842 161.738 156.093 1.00 85.99  ? 1157 LEU A C   1 
ATOM   7226 O O   . LEU A 1 1035 ? 144.581 161.611 154.894 1.00 98.54  ? 1157 LEU A O   1 
ATOM   7227 C CB  . LEU A 1 1035 ? 146.716 163.370 156.100 1.00 80.69  ? 1157 LEU A CB  1 
ATOM   7228 C CG  . LEU A 1 1035 ? 147.952 164.067 156.661 1.00 90.85  ? 1157 LEU A CG  1 
ATOM   7229 C CD1 . LEU A 1 1035 ? 149.195 163.675 155.894 1.00 95.18  ? 1157 LEU A CD1 1 
ATOM   7230 C CD2 . LEU A 1 1035 ? 147.750 165.565 156.583 1.00 90.48  ? 1157 LEU A CD2 1 
ATOM   7231 N N   . VAL A 1 1036 ? 143.920 161.681 157.046 1.00 80.66  ? 1158 VAL A N   1 
ATOM   7232 C CA  . VAL A 1 1036 ? 142.494 161.597 156.751 1.00 85.23  ? 1158 VAL A CA  1 
ATOM   7233 C C   . VAL A 1 1036 ? 141.828 162.818 157.364 1.00 85.90  ? 1158 VAL A C   1 
ATOM   7234 O O   . VAL A 1 1036 ? 141.861 163.004 158.586 1.00 90.48  ? 1158 VAL A O   1 
ATOM   7235 C CB  . VAL A 1 1036 ? 141.871 160.295 157.276 1.00 86.23  ? 1158 VAL A CB  1 
ATOM   7236 C CG1 . VAL A 1 1036 ? 140.350 160.343 157.190 1.00 96.20  ? 1158 VAL A CG1 1 
ATOM   7237 C CG2 . VAL A 1 1036 ? 142.372 159.124 156.477 1.00 99.44  ? 1158 VAL A CG2 1 
ATOM   7238 N N   . ARG A 1 1037 ? 141.240 163.655 156.517 1.00 85.01  ? 1159 ARG A N   1 
ATOM   7239 C CA  . ARG A 1 1037 ? 140.482 164.801 156.989 1.00 83.22  ? 1159 ARG A CA  1 
ATOM   7240 C C   . ARG A 1 1037 ? 139.110 164.343 157.461 1.00 85.40  ? 1159 ARG A C   1 
ATOM   7241 O O   . ARG A 1 1037 ? 138.547 163.383 156.929 1.00 96.41  ? 1159 ARG A O   1 
ATOM   7242 C CB  . ARG A 1 1037 ? 140.348 165.844 155.881 1.00 88.20  ? 1159 ARG A CB  1 
ATOM   7243 C CG  . ARG A 1 1037 ? 140.410 167.275 156.373 1.00 84.83  ? 1159 ARG A CG  1 
ATOM   7244 C CD  . ARG A 1 1037 ? 140.656 168.247 155.233 1.00 84.22  ? 1159 ARG A CD  1 
ATOM   7245 N NE  . ARG A 1 1037 ? 139.424 168.618 154.549 1.00 94.32  ? 1159 ARG A NE  1 
ATOM   7246 C CZ  . ARG A 1 1037 ? 139.068 168.173 153.352 1.00 100.00 ? 1159 ARG A CZ  1 
ATOM   7247 N NH1 . ARG A 1 1037 ? 139.836 167.341 152.668 1.00 95.50  ? 1159 ARG A NH1 1 
ATOM   7248 N NH2 . ARG A 1 1037 ? 137.916 168.577 152.826 1.00 98.68  ? 1159 ARG A NH2 1 
ATOM   7249 N N   . LEU A 1 1038 ? 138.583 165.020 158.482 1.00 80.81  ? 1160 LEU A N   1 
ATOM   7250 C CA  . LEU A 1 1038 ? 137.302 164.610 159.050 1.00 88.79  ? 1160 LEU A CA  1 
ATOM   7251 C C   . LEU A 1 1038 ? 136.134 165.055 158.177 1.00 95.40  ? 1160 LEU A C   1 
ATOM   7252 O O   . LEU A 1 1038 ? 135.067 164.430 158.196 1.00 95.10  ? 1160 LEU A O   1 
ATOM   7253 C CB  . LEU A 1 1038 ? 137.158 165.157 160.469 1.00 88.43  ? 1160 LEU A CB  1 
ATOM   7254 C CG  . LEU A 1 1038 ? 138.172 164.650 161.501 1.00 85.61  ? 1160 LEU A CG  1 
ATOM   7255 C CD1 . LEU A 1 1038 ? 137.886 165.246 162.867 1.00 76.89  ? 1160 LEU A CD1 1 
ATOM   7256 C CD2 . LEU A 1 1038 ? 138.189 163.132 161.568 1.00 83.02  ? 1160 LEU A CD2 1 
ATOM   7257 N N   . ALA A 1 1039 ? 136.310 166.137 157.416 1.00 97.76  ? 1161 ALA A N   1 
ATOM   7258 C CA  . ALA A 1 1039 ? 135.251 166.590 156.520 1.00 98.26  ? 1161 ALA A CA  1 
ATOM   7259 C C   . ALA A 1 1039 ? 135.178 165.731 155.264 1.00 98.97  ? 1161 ALA A C   1 
ATOM   7260 O O   . ALA A 1 1039 ? 134.086 165.443 154.763 1.00 102.94 ? 1161 ALA A O   1 
ATOM   7261 C CB  . ALA A 1 1039 ? 135.465 168.059 156.156 1.00 94.44  ? 1161 ALA A CB  1 
ATOM   7262 N N   . ALA A 1 1040 ? 136.328 165.309 154.741 1.00 93.91  ? 1162 ALA A N   1 
ATOM   7263 C CA  . ALA A 1 1040 ? 136.401 164.474 153.543 1.00 94.95  ? 1162 ALA A CA  1 
ATOM   7264 C C   . ALA A 1 1040 ? 137.178 163.212 153.890 1.00 99.97  ? 1162 ALA A C   1 
ATOM   7265 O O   . ALA A 1 1040 ? 138.405 163.166 153.729 1.00 98.72  ? 1162 ALA A O   1 
ATOM   7266 C CB  . ALA A 1 1040 ? 137.053 165.222 152.380 1.00 93.50  ? 1162 ALA A CB  1 
ATOM   7267 N N   . PRO A 1 1041 ? 136.496 162.166 154.375 1.00 106.05 ? 1163 PRO A N   1 
ATOM   7268 C CA  . PRO A 1 1041 ? 137.225 160.964 154.812 1.00 102.87 ? 1163 PRO A CA  1 
ATOM   7269 C C   . PRO A 1 1041 ? 137.696 160.072 153.678 1.00 109.24 ? 1163 PRO A C   1 
ATOM   7270 O O   . PRO A 1 1041 ? 138.583 159.242 153.902 1.00 111.72 ? 1163 PRO A O   1 
ATOM   7271 C CB  . PRO A 1 1041 ? 136.195 160.238 155.691 1.00 97.26  ? 1163 PRO A CB  1 
ATOM   7272 C CG  . PRO A 1 1041 ? 135.146 161.259 156.000 1.00 97.95  ? 1163 PRO A CG  1 
ATOM   7273 C CD  . PRO A 1 1041 ? 135.080 162.088 154.768 1.00 105.65 ? 1163 PRO A CD  1 
ATOM   7274 N N   . LEU A 1 1042 ? 137.133 160.216 152.474 1.00 112.66 ? 1164 LEU A N   1 
ATOM   7275 C CA  . LEU A 1 1042 ? 137.428 159.278 151.393 1.00 116.03 ? 1164 LEU A CA  1 
ATOM   7276 C C   . LEU A 1 1042 ? 138.789 159.547 150.760 1.00 112.54 ? 1164 LEU A C   1 
ATOM   7277 O O   . LEU A 1 1042 ? 139.444 158.623 150.266 1.00 111.73 ? 1164 LEU A O   1 
ATOM   7278 C CB  . LEU A 1 1042 ? 136.324 159.337 150.337 1.00 123.58 ? 1164 LEU A CB  1 
ATOM   7279 C CG  . LEU A 1 1042 ? 134.904 159.075 150.841 1.00 124.65 ? 1164 LEU A CG  1 
ATOM   7280 C CD1 . LEU A 1 1042 ? 133.899 159.240 149.713 1.00 126.78 ? 1164 LEU A CD1 1 
ATOM   7281 C CD2 . LEU A 1 1042 ? 134.798 157.690 151.458 1.00 114.47 ? 1164 LEU A CD2 1 
ATOM   7282 N N   . ASP A 1 1043 ? 139.232 160.801 150.766 1.00 113.27 ? 1165 ASP A N   1 
ATOM   7283 C CA  . ASP A 1 1043 ? 140.539 161.161 150.231 1.00 115.09 ? 1165 ASP A CA  1 
ATOM   7284 C C   . ASP A 1 1043 ? 141.583 161.049 151.336 1.00 110.36 ? 1165 ASP A C   1 
ATOM   7285 O O   . ASP A 1 1043 ? 141.616 161.877 152.253 1.00 106.50 ? 1165 ASP A O   1 
ATOM   7286 C CB  . ASP A 1 1043 ? 140.518 162.572 149.645 1.00 119.83 ? 1165 ASP A CB  1 
ATOM   7287 C CG  . ASP A 1 1043 ? 139.680 162.669 148.386 1.00 125.01 ? 1165 ASP A CG  1 
ATOM   7288 O OD1 . ASP A 1 1043 ? 139.575 161.659 147.658 1.00 129.19 ? 1165 ASP A OD1 1 
ATOM   7289 O OD2 . ASP A 1 1043 ? 139.129 163.756 148.121 1.00 117.78 ? 1165 ASP A OD2 1 
ATOM   7290 N N   . VAL A 1 1044 ? 142.428 160.029 151.246 1.00 109.46 ? 1166 VAL A N   1 
ATOM   7291 C CA  . VAL A 1 1044 ? 143.486 159.780 152.217 1.00 103.57 ? 1166 VAL A CA  1 
ATOM   7292 C C   . VAL A 1 1044 ? 144.772 160.352 151.644 1.00 99.64  ? 1166 VAL A C   1 
ATOM   7293 O O   . VAL A 1 1044 ? 145.337 159.800 150.695 1.00 100.58 ? 1166 VAL A O   1 
ATOM   7294 C CB  . VAL A 1 1044 ? 143.632 158.285 152.520 1.00 105.61 ? 1166 VAL A CB  1 
ATOM   7295 C CG1 . VAL A 1 1044 ? 144.662 158.062 153.615 1.00 97.12  ? 1166 VAL A CG1 1 
ATOM   7296 C CG2 . VAL A 1 1044 ? 142.296 157.706 152.911 1.00 106.35 ? 1166 VAL A CG2 1 
ATOM   7297 N N   . MET A 1 1045 ? 145.236 161.461 152.210 1.00 94.33  ? 1167 MET A N   1 
ATOM   7298 C CA  . MET A 1 1045 ? 146.404 162.133 151.665 1.00 93.88  ? 1167 MET A CA  1 
ATOM   7299 C C   . MET A 1 1045 ? 147.690 161.444 152.104 1.00 87.93  ? 1167 MET A C   1 
ATOM   7300 O O   . MET A 1 1045 ? 147.834 161.009 153.246 1.00 88.28  ? 1167 MET A O   1 
ATOM   7301 C CB  . MET A 1 1045 ? 146.421 163.601 152.083 1.00 95.36  ? 1167 MET A CB  1 
ATOM   7302 C CG  . MET A 1 1045 ? 145.292 164.415 151.483 1.00 103.01 ? 1167 MET A CG  1 
ATOM   7303 S SD  . MET A 1 1045 ? 145.371 166.152 151.937 1.00 119.84 ? 1167 MET A SD  1 
ATOM   7304 C CE  . MET A 1 1045 ? 144.836 166.069 153.641 1.00 98.00  ? 1167 MET A CE  1 
ATOM   7305 N N   . GLU A 1 1046 ? 148.629 161.353 151.170 1.00 95.68  ? 1168 GLU A N   1 
ATOM   7306 C CA  . GLU A 1 1046 ? 149.931 160.740 151.384 1.00 97.06  ? 1168 GLU A CA  1 
ATOM   7307 C C   . GLU A 1 1046 ? 150.949 161.856 151.532 1.00 94.32  ? 1168 GLU A C   1 
ATOM   7308 O O   . GLU A 1 1046 ? 150.990 162.775 150.709 1.00 99.23  ? 1168 GLU A O   1 
ATOM   7309 C CB  . GLU A 1 1046 ? 150.264 159.796 150.210 1.00 106.64 ? 1168 GLU A CB  1 
ATOM   7310 C CG  . GLU A 1 1046 ? 151.493 158.870 150.324 1.00 109.34 ? 1168 GLU A CG  1 
ATOM   7311 C CD  . GLU A 1 1046 ? 152.810 159.536 149.931 1.00 113.39 ? 1168 GLU A CD  1 
ATOM   7312 O OE1 . GLU A 1 1046 ? 152.780 160.459 149.091 1.00 109.68 ? 1168 GLU A OE1 1 
ATOM   7313 O OE2 . GLU A 1 1046 ? 153.870 159.140 150.457 1.00 114.39 ? 1168 GLU A OE2 1 
ATOM   7314 N N   . LEU A 1 1047 ? 151.762 161.784 152.580 1.00 88.63  ? 1169 LEU A N   1 
ATOM   7315 C CA  . LEU A 1 1047 ? 152.791 162.784 152.772 1.00 94.47  ? 1169 LEU A CA  1 
ATOM   7316 C C   . LEU A 1 1047 ? 154.129 162.059 152.800 1.00 90.63  ? 1169 LEU A C   1 
ATOM   7317 O O   . LEU A 1 1047 ? 154.301 161.151 153.626 1.00 87.41  ? 1169 LEU A O   1 
ATOM   7318 C CB  . LEU A 1 1047 ? 152.540 163.577 154.064 1.00 90.95  ? 1169 LEU A CB  1 
ATOM   7319 C CG  . LEU A 1 1047 ? 153.309 164.836 154.505 1.00 84.89  ? 1169 LEU A CG  1 
ATOM   7320 C CD1 . LEU A 1 1047 ? 152.399 165.657 155.391 1.00 83.56  ? 1169 LEU A CD1 1 
ATOM   7321 C CD2 . LEU A 1 1047 ? 154.588 164.607 155.244 1.00 86.51  ? 1169 LEU A CD2 1 
ATOM   7322 N N   . PRO A 1 1048 ? 155.065 162.366 151.895 1.00 96.18  ? 1170 PRO A N   1 
ATOM   7323 C CA  . PRO A 1 1048 ? 156.350 161.656 151.896 1.00 96.65  ? 1170 PRO A CA  1 
ATOM   7324 C C   . PRO A 1 1048 ? 157.256 162.087 153.040 1.00 94.42  ? 1170 PRO A C   1 
ATOM   7325 O O   . PRO A 1 1048 ? 157.312 163.260 153.415 1.00 94.31  ? 1170 PRO A O   1 
ATOM   7326 C CB  . PRO A 1 1048 ? 156.959 162.027 150.540 1.00 103.21 ? 1170 PRO A CB  1 
ATOM   7327 C CG  . PRO A 1 1048 ? 155.803 162.396 149.693 1.00 103.27 ? 1170 PRO A CG  1 
ATOM   7328 C CD  . PRO A 1 1048 ? 154.845 163.072 150.621 1.00 99.10  ? 1170 PRO A CD  1 
ATOM   7329 N N   . THR A 1 1049 ? 157.954 161.109 153.595 1.00 95.15  ? 1171 THR A N   1 
ATOM   7330 C CA  . THR A 1 1049 ? 158.930 161.352 154.644 1.00 92.71  ? 1171 THR A CA  1 
ATOM   7331 C C   . THR A 1 1049 ? 160.189 161.976 154.037 1.00 94.83  ? 1171 THR A C   1 
ATOM   7332 O O   . THR A 1 1049 ? 160.614 161.549 152.954 1.00 105.03 ? 1171 THR A O   1 
ATOM   7333 C CB  . THR A 1 1049 ? 159.232 160.020 155.334 1.00 93.00  ? 1171 THR A CB  1 
ATOM   7334 O OG1 . THR A 1 1049 ? 158.010 159.474 155.839 1.00 96.16  ? 1171 THR A OG1 1 
ATOM   7335 C CG2 . THR A 1 1049 ? 160.169 160.177 156.484 1.00 87.90  ? 1171 THR A CG2 1 
ATOM   7336 N N   . PRO A 1 1050 ? 160.764 163.022 154.655 1.00 91.17  ? 1172 PRO A N   1 
ATOM   7337 C CA  . PRO A 1 1050 ? 161.974 163.654 154.099 1.00 98.67  ? 1172 PRO A CA  1 
ATOM   7338 C C   . PRO A 1 1050 ? 163.212 162.775 154.209 1.00 102.91 ? 1172 PRO A C   1 
ATOM   7339 O O   . PRO A 1 1050 ? 163.260 161.844 155.011 1.00 103.91 ? 1172 PRO A O   1 
ATOM   7340 C CB  . PRO A 1 1050 ? 162.119 164.923 154.942 1.00 90.99  ? 1172 PRO A CB  1 
ATOM   7341 C CG  . PRO A 1 1050 ? 160.743 165.206 155.400 1.00 81.69  ? 1172 PRO A CG  1 
ATOM   7342 C CD  . PRO A 1 1050 ? 160.175 163.866 155.708 1.00 84.56  ? 1172 PRO A CD  1 
ATOM   7343 N N   . ASP A 1 1051 ? 164.227 163.106 153.403 1.00 104.99 ? 1173 ASP A N   1 
ATOM   7344 C CA  . ASP A 1 1051 ? 165.265 162.140 153.047 1.00 110.54 ? 1173 ASP A CA  1 
ATOM   7345 C C   . ASP A 1 1051 ? 166.310 161.990 154.152 1.00 110.18 ? 1173 ASP A C   1 
ATOM   7346 O O   . ASP A 1 1051 ? 166.940 160.934 154.281 1.00 114.45 ? 1173 ASP A O   1 
ATOM   7347 C CB  . ASP A 1 1051 ? 165.926 162.568 151.734 1.00 119.73 ? 1173 ASP A CB  1 
ATOM   7348 C CG  . ASP A 1 1051 ? 166.601 161.419 151.001 1.00 128.45 ? 1173 ASP A CG  1 
ATOM   7349 O OD1 . ASP A 1 1051 ? 166.503 160.259 151.449 1.00 128.23 ? 1173 ASP A OD1 1 
ATOM   7350 O OD2 . ASP A 1 1051 ? 167.241 161.682 149.961 1.00 131.07 ? 1173 ASP A OD2 1 
ATOM   7351 N N   . GLN A 1 1052 ? 166.486 163.021 154.985 1.00 104.30 ? 1174 GLN A N   1 
ATOM   7352 C CA  . GLN A 1 1052 ? 167.457 162.924 156.075 1.00 103.78 ? 1174 GLN A CA  1 
ATOM   7353 C C   . GLN A 1 1052 ? 166.868 162.292 157.331 1.00 102.40 ? 1174 GLN A C   1 
ATOM   7354 O O   . GLN A 1 1052 ? 167.572 162.144 158.335 1.00 102.91 ? 1174 GLN A O   1 
ATOM   7355 C CB  . GLN A 1 1052 ? 168.068 164.295 156.396 1.00 103.40 ? 1174 GLN A CB  1 
ATOM   7356 C CG  . GLN A 1 1052 ? 168.977 164.911 155.313 1.00 113.51 ? 1174 GLN A CG  1 
ATOM   7357 C CD  . GLN A 1 1052 ? 168.248 165.621 154.191 1.00 122.41 ? 1174 GLN A CD  1 
ATOM   7358 O OE1 . GLN A 1 1052 ? 167.077 165.961 154.313 1.00 119.39 ? 1174 GLN A OE1 1 
ATOM   7359 N NE2 . GLN A 1 1052 ? 168.948 165.853 153.085 1.00 121.39 ? 1174 GLN A NE2 1 
ATOM   7360 N N   . ALA A 1 1053 ? 165.592 161.921 157.304 1.00 101.32 ? 1175 ALA A N   1 
ATOM   7361 C CA  . ALA A 1 1053 ? 164.983 161.092 158.335 1.00 97.77  ? 1175 ALA A CA  1 
ATOM   7362 C C   . ALA A 1 1053 ? 164.115 160.003 157.716 1.00 100.05 ? 1175 ALA A C   1 
ATOM   7363 O O   . ALA A 1 1053 ? 163.014 159.737 158.192 1.00 103.73 ? 1175 ALA A O   1 
ATOM   7364 C CB  . ALA A 1 1053 ? 164.163 161.940 159.301 1.00 89.16  ? 1175 ALA A CB  1 
ATOM   7365 N N   . SER A 1 1054 ? 164.635 159.331 156.679 1.00 101.12 ? 1176 SER A N   1 
ATOM   7366 C CA  . SER A 1 1054 ? 163.783 158.605 155.734 1.00 104.04 ? 1176 SER A CA  1 
ATOM   7367 C C   . SER A 1 1054 ? 163.222 157.270 156.234 1.00 105.11 ? 1176 SER A C   1 
ATOM   7368 O O   . SER A 1 1054 ? 162.096 156.933 155.831 1.00 106.97 ? 1176 SER A O   1 
ATOM   7369 C CB  . SER A 1 1054 ? 164.514 158.459 154.391 1.00 107.49 ? 1176 SER A CB  1 
ATOM   7370 O OG  . SER A 1 1054 ? 163.716 157.746 153.464 1.00 110.11 ? 1176 SER A OG  1 
ATOM   7371 N N   . PRO A 1 1055 ? 163.915 156.442 157.077 1.00 101.63 ? 1177 PRO A N   1 
ATOM   7372 C CA  . PRO A 1 1055 ? 163.120 155.549 157.933 1.00 95.26  ? 1177 PRO A CA  1 
ATOM   7373 C C   . PRO A 1 1055 ? 162.708 156.270 159.207 1.00 94.00  ? 1177 PRO A C   1 
ATOM   7374 O O   . PRO A 1 1055 ? 163.539 156.580 160.066 1.00 94.46  ? 1177 PRO A O   1 
ATOM   7375 C CB  . PRO A 1 1055 ? 164.073 154.375 158.203 1.00 97.28  ? 1177 PRO A CB  1 
ATOM   7376 C CG  . PRO A 1 1055 ? 165.415 154.844 157.934 1.00 98.81  ? 1177 PRO A CG  1 
ATOM   7377 C CD  . PRO A 1 1055 ? 165.342 156.036 157.060 1.00 101.54 ? 1177 PRO A CD  1 
ATOM   7378 N N   . ALA A 1 1056 ? 161.414 156.540 159.335 1.00 90.92  ? 1178 ALA A N   1 
ATOM   7379 C CA  . ALA A 1 1056 ? 160.892 157.326 160.443 1.00 88.01  ? 1178 ALA A CA  1 
ATOM   7380 C C   . ALA A 1 1056 ? 160.076 156.442 161.374 1.00 89.22  ? 1178 ALA A C   1 
ATOM   7381 O O   . ALA A 1 1056 ? 159.398 155.512 160.931 1.00 93.53  ? 1178 ALA A O   1 
ATOM   7382 C CB  . ALA A 1 1056 ? 160.029 158.484 159.941 1.00 84.42  ? 1178 ALA A CB  1 
ATOM   7383 N N   . SER A 1 1057 ? 160.151 156.731 162.670 1.00 78.43  ? 1179 SER A N   1 
ATOM   7384 C CA  . SER A 1 1057 ? 159.372 155.997 163.652 1.00 78.04  ? 1179 SER A CA  1 
ATOM   7385 C C   . SER A 1 1057 ? 158.454 156.877 164.481 1.00 80.87  ? 1179 SER A C   1 
ATOM   7386 O O   . SER A 1 1057 ? 157.665 156.345 165.267 1.00 83.38  ? 1179 SER A O   1 
ATOM   7387 C CB  . SER A 1 1057 ? 160.300 155.222 164.590 1.00 80.62  ? 1179 SER A CB  1 
ATOM   7388 O OG  . SER A 1 1057 ? 161.086 156.120 165.339 1.00 83.88  ? 1179 SER A OG  1 
ATOM   7389 N N   . ALA A 1 1058 ? 158.535 158.195 164.330 1.00 78.78  ? 1180 ALA A N   1 
ATOM   7390 C CA  . ALA A 1 1058 ? 157.674 159.109 165.060 1.00 69.40  ? 1180 ALA A CA  1 
ATOM   7391 C C   . ALA A 1 1058 ? 157.336 160.307 164.192 1.00 70.35  ? 1180 ALA A C   1 
ATOM   7392 O O   . ALA A 1 1058 ? 158.200 160.847 163.500 1.00 75.97  ? 1180 ALA A O   1 
ATOM   7393 C CB  . ALA A 1 1058 ? 158.334 159.589 166.349 1.00 65.88  ? 1180 ALA A CB  1 
ATOM   7394 N N   . LEU A 1 1059 ? 156.073 160.711 164.236 1.00 67.95  ? 1181 LEU A N   1 
ATOM   7395 C CA  . LEU A 1 1059 ? 155.612 161.943 163.619 1.00 61.74  ? 1181 LEU A CA  1 
ATOM   7396 C C   . LEU A 1 1059 ? 154.659 162.628 164.581 1.00 67.93  ? 1181 LEU A C   1 
ATOM   7397 O O   . LEU A 1 1059 ? 153.780 161.986 165.162 1.00 77.83  ? 1181 LEU A O   1 
ATOM   7398 C CB  . LEU A 1 1059 ? 154.927 161.681 162.280 1.00 66.22  ? 1181 LEU A CB  1 
ATOM   7399 C CG  . LEU A 1 1059 ? 154.438 162.874 161.459 1.00 66.19  ? 1181 LEU A CG  1 
ATOM   7400 C CD1 . LEU A 1 1059 ? 155.483 163.965 161.331 1.00 60.66  ? 1181 LEU A CD1 1 
ATOM   7401 C CD2 . LEU A 1 1059 ? 154.024 162.397 160.105 1.00 70.38  ? 1181 LEU A CD2 1 
ATOM   7402 N N   . GLN A 1 1060 ? 154.833 163.935 164.742 1.00 60.28  ? 1182 GLN A N   1 
ATOM   7403 C CA  . GLN A 1 1060 ? 154.122 164.672 165.770 1.00 56.50  ? 1182 GLN A CA  1 
ATOM   7404 C C   . GLN A 1 1060 ? 153.964 166.129 165.365 1.00 57.21  ? 1182 GLN A C   1 
ATOM   7405 O O   . GLN A 1 1060 ? 154.961 166.814 165.126 1.00 64.90  ? 1182 GLN A O   1 
ATOM   7406 C CB  . GLN A 1 1060 ? 154.880 164.552 167.089 1.00 61.92  ? 1182 GLN A CB  1 
ATOM   7407 C CG  . GLN A 1 1060 ? 154.027 164.577 168.325 1.00 73.96  ? 1182 GLN A CG  1 
ATOM   7408 C CD  . GLN A 1 1060 ? 154.818 164.221 169.557 1.00 73.59  ? 1182 GLN A CD  1 
ATOM   7409 O OE1 . GLN A 1 1060 ? 156.019 164.470 169.627 1.00 70.76  ? 1182 GLN A OE1 1 
ATOM   7410 N NE2 . GLN A 1 1060 ? 154.149 163.636 170.541 1.00 80.51  ? 1182 GLN A NE2 1 
ATOM   7411 N N   . LEU A 1 1061 ? 152.729 166.609 165.269 1.00 58.01  ? 1183 LEU A N   1 
ATOM   7412 C CA  . LEU A 1 1061 ? 152.508 168.030 165.047 1.00 60.88  ? 1183 LEU A CA  1 
ATOM   7413 C C   . LEU A 1 1061 ? 152.759 168.789 166.340 1.00 69.36  ? 1183 LEU A C   1 
ATOM   7414 O O   . LEU A 1 1061 ? 152.206 168.446 167.389 1.00 72.33  ? 1183 LEU A O   1 
ATOM   7415 C CB  . LEU A 1 1061 ? 151.088 168.289 164.547 1.00 61.15  ? 1183 LEU A CB  1 
ATOM   7416 C CG  . LEU A 1 1061 ? 150.702 169.757 164.345 1.00 57.92  ? 1183 LEU A CG  1 
ATOM   7417 C CD1 . LEU A 1 1061 ? 151.353 170.312 163.099 1.00 60.69  ? 1183 LEU A CD1 1 
ATOM   7418 C CD2 . LEU A 1 1061 ? 149.198 169.931 164.284 1.00 63.55  ? 1183 LEU A CD2 1 
ATOM   7419 N N   . LEU A 1 1062 ? 153.607 169.807 166.266 1.00 66.56  ? 1184 LEU A N   1 
ATOM   7420 C CA  . LEU A 1 1062 ? 153.992 170.563 167.444 1.00 64.60  ? 1184 LEU A CA  1 
ATOM   7421 C C   . LEU A 1 1062 ? 152.892 171.527 167.854 1.00 72.49  ? 1184 LEU A C   1 
ATOM   7422 O O   . LEU A 1 1062 ? 152.202 172.102 167.009 1.00 76.45  ? 1184 LEU A O   1 
ATOM   7423 C CB  . LEU A 1 1062 ? 155.280 171.334 167.178 1.00 63.27  ? 1184 LEU A CB  1 
ATOM   7424 C CG  . LEU A 1 1062 ? 156.575 170.538 167.048 1.00 57.29  ? 1184 LEU A CG  1 
ATOM   7425 C CD1 . LEU A 1 1062 ? 157.719 171.506 166.985 1.00 60.96  ? 1184 LEU A CD1 1 
ATOM   7426 C CD2 . LEU A 1 1062 ? 156.758 169.583 168.210 1.00 58.21  ? 1184 LEU A CD2 1 
ATOM   7427 N N   . ASP A 1 1063 ? 152.724 171.680 169.158 1.00 78.09  ? 1185 ASP A N   1 
ATOM   7428 C CA  . ASP A 1 1063 ? 151.805 172.674 169.689 1.00 80.50  ? 1185 ASP A CA  1 
ATOM   7429 C C   . ASP A 1 1063 ? 152.419 174.058 169.511 1.00 84.86  ? 1185 ASP A C   1 
ATOM   7430 O O   . ASP A 1 1063 ? 153.582 174.258 169.883 1.00 90.29  ? 1185 ASP A O   1 
ATOM   7431 C CB  . ASP A 1 1063 ? 151.530 172.392 171.163 1.00 90.40  ? 1185 ASP A CB  1 
ATOM   7432 C CG  . ASP A 1 1063 ? 150.219 172.981 171.641 1.00 103.33 ? 1185 ASP A CG  1 
ATOM   7433 O OD1 . ASP A 1 1063 ? 149.310 173.179 170.812 1.00 103.28 ? 1185 ASP A OD1 1 
ATOM   7434 O OD2 . ASP A 1 1063 ? 150.097 173.242 172.856 1.00 108.87 ? 1185 ASP A OD2 1 
ATOM   7435 N N   . PRO A 1 1064 ? 151.705 175.016 168.903 1.00 87.02  ? 1186 PRO A N   1 
ATOM   7436 C CA  . PRO A 1 1064 ? 152.291 176.359 168.742 1.00 91.30  ? 1186 PRO A CA  1 
ATOM   7437 C C   . PRO A 1 1064 ? 152.337 177.155 170.034 1.00 92.46  ? 1186 PRO A C   1 
ATOM   7438 O O   . PRO A 1 1064 ? 153.305 177.889 170.269 1.00 91.19  ? 1186 PRO A O   1 
ATOM   7439 C CB  . PRO A 1 1064 ? 151.383 177.013 167.693 1.00 98.51  ? 1186 PRO A CB  1 
ATOM   7440 C CG  . PRO A 1 1064 ? 150.098 176.265 167.770 1.00 95.09  ? 1186 PRO A CG  1 
ATOM   7441 C CD  . PRO A 1 1064 ? 150.460 174.862 168.128 1.00 91.17  ? 1186 PRO A CD  1 
ATOM   7442 N N   . GLN A 1 1065 ? 151.325 177.026 170.879 1.00 97.05  ? 1187 GLN A N   1 
ATOM   7443 C CA  . GLN A 1 1065 ? 151.319 177.600 172.213 1.00 100.55 ? 1187 GLN A CA  1 
ATOM   7444 C C   . GLN A 1 1065 ? 152.202 176.764 173.135 1.00 99.35  ? 1187 GLN A C   1 
ATOM   7445 O O   . GLN A 1 1065 ? 152.359 175.560 172.908 1.00 100.97 ? 1187 GLN A O   1 
ATOM   7446 C CB  . GLN A 1 1065 ? 149.896 177.653 172.763 1.00 102.08 ? 1187 GLN A CB  1 
ATOM   7447 C CG  . GLN A 1 1065 ? 148.938 178.453 171.900 1.00 107.47 ? 1187 GLN A CG  1 
ATOM   7448 C CD  . GLN A 1 1065 ? 149.324 179.917 171.804 1.00 109.72 ? 1187 GLN A CD  1 
ATOM   7449 O OE1 . GLN A 1 1065 ? 149.699 180.539 172.798 1.00 105.66 ? 1187 GLN A OE1 1 
ATOM   7450 N NE2 . GLN A 1 1065 ? 149.240 180.472 170.601 1.00 109.07 ? 1187 GLN A NE2 1 
ATOM   7451 N N   . PRO A 1 1066 ? 152.813 177.349 174.168 1.00 102.87 ? 1188 PRO A N   1 
ATOM   7452 C CA  . PRO A 1 1066 ? 153.539 176.535 175.150 1.00 100.83 ? 1188 PRO A CA  1 
ATOM   7453 C C   . PRO A 1 1066 ? 152.585 175.796 176.075 1.00 94.87  ? 1188 PRO A C   1 
ATOM   7454 O O   . PRO A 1 1066 ? 151.375 176.036 176.100 1.00 95.66  ? 1188 PRO A O   1 
ATOM   7455 C CB  . PRO A 1 1066 ? 154.375 177.563 175.917 1.00 98.23  ? 1188 PRO A CB  1 
ATOM   7456 C CG  . PRO A 1 1066 ? 153.638 178.833 175.753 1.00 96.31  ? 1188 PRO A CG  1 
ATOM   7457 C CD  . PRO A 1 1066 ? 153.077 178.785 174.368 1.00 100.76 ? 1188 PRO A CD  1 
ATOM   7458 N N   . LEU A 1 1067 ? 153.157 174.864 176.830 1.00 87.91  ? 1189 LEU A N   1 
ATOM   7459 C CA  . LEU A 1 1067 ? 152.381 174.104 177.801 1.00 88.29  ? 1189 LEU A CA  1 
ATOM   7460 C C   . LEU A 1 1067 ? 152.039 174.989 178.992 1.00 88.74  ? 1189 LEU A C   1 
ATOM   7461 O O   . LEU A 1 1067 ? 152.877 175.799 179.411 1.00 91.47  ? 1189 LEU A O   1 
ATOM   7462 C CB  . LEU A 1 1067 ? 153.151 172.873 178.272 1.00 87.88  ? 1189 LEU A CB  1 
ATOM   7463 C CG  . LEU A 1 1067 ? 152.872 171.533 177.590 1.00 88.95  ? 1189 LEU A CG  1 
ATOM   7464 C CD1 . LEU A 1 1067 ? 153.600 170.432 178.315 1.00 71.22  ? 1189 LEU A CD1 1 
ATOM   7465 C CD2 . LEU A 1 1067 ? 151.389 171.223 177.528 1.00 88.68  ? 1189 LEU A CD2 1 
ATOM   7466 N N   . PRO A 1 1068 ? 150.811 174.919 179.516 1.00 84.66  ? 1190 PRO A N   1 
ATOM   7467 C CA  . PRO A 1 1068 ? 150.488 175.672 180.721 1.00 86.55  ? 1190 PRO A CA  1 
ATOM   7468 C C   . PRO A 1 1068 ? 151.148 175.036 181.934 1.00 89.05  ? 1190 PRO A C   1 
ATOM   7469 O O   . PRO A 1 1068 ? 151.433 173.828 181.932 1.00 91.59  ? 1190 PRO A O   1 
ATOM   7470 C CB  . PRO A 1 1068 ? 148.953 175.577 180.799 1.00 83.65  ? 1190 PRO A CB  1 
ATOM   7471 C CG  . PRO A 1 1068 ? 148.516 175.100 179.460 1.00 84.28  ? 1190 PRO A CG  1 
ATOM   7472 C CD  . PRO A 1 1068 ? 149.622 174.243 178.973 1.00 79.04  ? 1190 PRO A CD  1 
ATOM   7473 N N   . PRO A 1 1069 ? 151.415 175.808 182.990 1.00 88.07  ? 1191 PRO A N   1 
ATOM   7474 C CA  . PRO A 1 1069 ? 152.058 175.236 184.178 1.00 89.56  ? 1191 PRO A CA  1 
ATOM   7475 C C   . PRO A 1 1069 ? 151.069 174.471 185.058 1.00 91.30  ? 1191 PRO A C   1 
ATOM   7476 O O   . PRO A 1 1069 ? 149.907 174.258 184.710 1.00 88.79  ? 1191 PRO A O   1 
ATOM   7477 C CB  . PRO A 1 1069 ? 152.607 176.467 184.900 1.00 84.80  ? 1191 PRO A CB  1 
ATOM   7478 C CG  . PRO A 1 1069 ? 151.688 177.544 184.521 1.00 88.42  ? 1191 PRO A CG  1 
ATOM   7479 C CD  . PRO A 1 1069 ? 151.349 177.280 183.091 1.00 88.30  ? 1191 PRO A CD  1 
ATOM   7480 N N   . ARG A 1 1070 ? 151.572 174.046 186.215 1.00 87.65  ? 1192 ARG A N   1 
ATOM   7481 C CA  . ARG A 1 1070 ? 150.777 173.266 187.152 1.00 81.92  ? 1192 ARG A CA  1 
ATOM   7482 C C   . ARG A 1 1070 ? 149.746 174.142 187.845 1.00 89.25  ? 1192 ARG A C   1 
ATOM   7483 O O   . ARG A 1 1070 ? 150.057 175.243 188.310 1.00 96.28  ? 1192 ARG A O   1 
ATOM   7484 C CB  . ARG A 1 1070 ? 151.677 172.616 188.196 1.00 82.70  ? 1192 ARG A CB  1 
ATOM   7485 C CG  . ARG A 1 1070 ? 152.710 171.677 187.639 1.00 84.84  ? 1192 ARG A CG  1 
ATOM   7486 C CD  . ARG A 1 1070 ? 153.351 170.901 188.765 1.00 94.04  ? 1192 ARG A CD  1 
ATOM   7487 N NE  . ARG A 1 1070 ? 154.414 170.028 188.290 1.00 98.12  ? 1192 ARG A NE  1 
ATOM   7488 C CZ  . ARG A 1 1070 ? 154.985 169.084 189.024 1.00 97.53  ? 1192 ARG A CZ  1 
ATOM   7489 N NH1 . ARG A 1 1070 ? 154.608 168.856 190.271 1.00 98.32  ? 1192 ARG A NH1 1 
ATOM   7490 N NH2 . ARG A 1 1070 ? 155.959 168.355 188.495 1.00 92.05  ? 1192 ARG A NH2 1 
ATOM   7491 N N   . ASP A 1 1071 ? 148.511 173.659 187.886 1.00 86.43  ? 1193 ASP A N   1 
ATOM   7492 C CA  . ASP A 1 1071 ? 147.457 174.334 188.622 1.00 88.46  ? 1193 ASP A CA  1 
ATOM   7493 C C   . ASP A 1 1071 ? 147.679 174.104 190.107 1.00 92.75  ? 1193 ASP A C   1 
ATOM   7494 O O   . ASP A 1 1071 ? 147.877 172.967 190.546 1.00 95.72  ? 1193 ASP A O   1 
ATOM   7495 C CB  . ASP A 1 1071 ? 146.090 173.799 188.194 1.00 85.96  ? 1193 ASP A CB  1 
ATOM   7496 C CG  . ASP A 1 1071 ? 144.957 174.791 188.419 1.00 95.16  ? 1193 ASP A CG  1 
ATOM   7497 O OD1 . ASP A 1 1071 ? 143.924 174.655 187.733 1.00 90.91  ? 1193 ASP A OD1 1 
ATOM   7498 O OD2 . ASP A 1 1071 ? 145.079 175.701 189.264 1.00 103.94 ? 1193 ASP A OD2 1 
ATOM   7499 N N   . GLU A 1 1072 ? 147.649 175.184 190.879 1.00 93.17  ? 1194 GLU A N   1 
ATOM   7500 C CA  . GLU A 1 1072 ? 147.616 175.091 192.329 1.00 94.36  ? 1194 GLU A CA  1 
ATOM   7501 C C   . GLU A 1 1072 ? 146.213 174.832 192.853 1.00 96.56  ? 1194 GLU A C   1 
ATOM   7502 O O   . GLU A 1 1072 ? 146.054 174.505 194.033 1.00 99.93  ? 1194 GLU A O   1 
ATOM   7503 C CB  . GLU A 1 1072 ? 148.175 176.373 192.955 1.00 95.75  ? 1194 GLU A CB  1 
ATOM   7504 C CG  . GLU A 1 1072 ? 149.517 176.862 192.399 1.00 104.23 ? 1194 GLU A CG  1 
ATOM   7505 C CD  . GLU A 1 1072 ? 150.682 175.919 192.667 1.00 113.20 ? 1194 GLU A CD  1 
ATOM   7506 O OE1 . GLU A 1 1072 ? 151.371 176.113 193.689 1.00 114.80 ? 1194 GLU A OE1 1 
ATOM   7507 O OE2 . GLU A 1 1072 ? 150.950 175.021 191.839 1.00 111.06 ? 1194 GLU A OE2 1 
ATOM   7508 N N   . GLY A 1 1073 ? 145.199 174.973 192.005 1.00 95.78  ? 1195 GLY A N   1 
ATOM   7509 C CA  . GLY A 1 1073 ? 143.824 174.696 192.330 1.00 98.79  ? 1195 GLY A CA  1 
ATOM   7510 C C   . GLY A 1 1073 ? 143.392 173.261 192.176 1.00 100.47 ? 1195 GLY A C   1 
ATOM   7511 O O   . GLY A 1 1073 ? 142.214 172.963 192.371 1.00 108.11 ? 1195 GLY A O   1 
ATOM   7512 N N   . VAL A 1 1074 ? 144.297 172.359 191.801 1.00 92.11  ? 1196 VAL A N   1 
ATOM   7513 C CA  . VAL A 1 1074 ? 144.025 170.927 191.849 1.00 84.14  ? 1196 VAL A CA  1 
ATOM   7514 C C   . VAL A 1 1074 ? 144.813 170.234 192.943 1.00 88.77  ? 1196 VAL A C   1 
ATOM   7515 O O   . VAL A 1 1074 ? 144.575 169.043 193.199 1.00 96.68  ? 1196 VAL A O   1 
ATOM   7516 C CB  . VAL A 1 1074 ? 144.296 170.244 190.492 1.00 80.90  ? 1196 VAL A CB  1 
ATOM   7517 C CG1 . VAL A 1 1074 ? 143.554 170.956 189.380 1.00 89.82  ? 1196 VAL A CG1 1 
ATOM   7518 C CG2 . VAL A 1 1074 ? 145.779 170.195 190.201 1.00 86.11  ? 1196 VAL A CG2 1 
ATOM   7519 N N   . ILE A 1 1075 ? 145.735 170.929 193.592 1.00 88.01  ? 1197 ILE A N   1 
ATOM   7520 C CA  . ILE A 1 1075 ? 146.495 170.355 194.702 1.00 89.80  ? 1197 ILE A CA  1 
ATOM   7521 C C   . ILE A 1 1075 ? 145.626 170.393 195.957 1.00 98.21  ? 1197 ILE A C   1 
ATOM   7522 O O   . ILE A 1 1075 ? 145.161 171.479 196.336 1.00 104.81 ? 1197 ILE A O   1 
ATOM   7523 C CB  . ILE A 1 1075 ? 147.789 171.126 194.915 1.00 85.14  ? 1197 ILE A CB  1 
ATOM   7524 C CG1 . ILE A 1 1075 ? 148.513 171.334 193.586 1.00 86.99  ? 1197 ILE A CG1 1 
ATOM   7525 C CG2 . ILE A 1 1075 ? 148.677 170.398 195.907 1.00 88.04  ? 1197 ILE A CG2 1 
ATOM   7526 C CD1 . ILE A 1 1075 ? 149.753 172.189 193.700 1.00 90.68  ? 1197 ILE A CD1 1 
ATOM   7527 N N   . PRO A 1 1076 ? 145.375 169.258 196.611 1.00 97.18  ? 1198 PRO A N   1 
ATOM   7528 C CA  . PRO A 1 1076 ? 144.672 169.297 197.897 1.00 98.44  ? 1198 PRO A CA  1 
ATOM   7529 C C   . PRO A 1 1076 ? 145.597 169.792 198.993 1.00 105.03 ? 1198 PRO A C   1 
ATOM   7530 O O   . PRO A 1 1076 ? 146.785 169.461 199.018 1.00 107.99 ? 1198 PRO A O   1 
ATOM   7531 C CB  . PRO A 1 1076 ? 144.266 167.838 198.135 1.00 95.24  ? 1198 PRO A CB  1 
ATOM   7532 C CG  . PRO A 1 1076 ? 144.662 167.089 196.907 1.00 90.68  ? 1198 PRO A CG  1 
ATOM   7533 C CD  . PRO A 1 1076 ? 145.716 167.880 196.226 1.00 91.74  ? 1198 PRO A CD  1 
ATOM   7534 N N   . MET A 1 1077 ? 145.052 170.595 199.899 1.00 106.68 ? 1199 MET A N   1 
ATOM   7535 C CA  . MET A 1 1077 ? 145.853 171.084 201.007 1.00 110.87 ? 1199 MET A CA  1 
ATOM   7536 C C   . MET A 1 1077 ? 145.990 169.999 202.067 1.00 112.51 ? 1199 MET A C   1 
ATOM   7537 O O   . MET A 1 1077 ? 145.207 169.045 202.115 1.00 108.18 ? 1199 MET A O   1 
ATOM   7538 C CB  . MET A 1 1077 ? 145.244 172.349 201.615 1.00 115.39 ? 1199 MET A CB  1 
ATOM   7539 C CG  . MET A 1 1077 ? 143.894 172.155 202.275 1.00 126.88 ? 1199 MET A CG  1 
ATOM   7540 S SD  . MET A 1 1077 ? 143.246 173.681 202.979 1.00 144.21 ? 1199 MET A SD  1 
ATOM   7541 C CE  . MET A 1 1077 ? 144.322 173.888 204.395 1.00 122.55 ? 1199 MET A CE  1 
ATOM   7542 N N   . THR A 1 1078 ? 147.018 170.141 202.896 1.00 113.84 ? 1200 THR A N   1 
ATOM   7543 C CA  . THR A 1 1078 ? 147.277 169.174 203.951 1.00 112.05 ? 1200 THR A CA  1 
ATOM   7544 C C   . THR A 1 1078 ? 146.280 169.356 205.087 1.00 116.93 ? 1200 THR A C   1 
ATOM   7545 O O   . THR A 1 1078 ? 145.987 170.481 205.503 1.00 120.24 ? 1200 THR A O   1 
ATOM   7546 C CB  . THR A 1 1078 ? 148.710 169.330 204.465 1.00 110.70 ? 1200 THR A CB  1 
ATOM   7547 O OG1 . THR A 1 1078 ? 149.594 169.526 203.357 1.00 111.16 ? 1200 THR A OG1 1 
ATOM   7548 C CG2 . THR A 1 1078 ? 149.155 168.093 205.227 1.00 110.78 ? 1200 THR A CG2 1 
ATOM   7549 N N   . VAL A 1 1079 ? 145.720 168.235 205.548 1.00 119.21 ? 1201 VAL A N   1 
ATOM   7550 C CA  . VAL A 1 1079 ? 144.833 168.230 206.704 1.00 119.30 ? 1201 VAL A CA  1 
ATOM   7551 C C   . VAL A 1 1079 ? 145.662 168.509 207.952 1.00 125.88 ? 1201 VAL A C   1 
ATOM   7552 O O   . VAL A 1 1079 ? 146.758 167.955 208.112 1.00 127.20 ? 1201 VAL A O   1 
ATOM   7553 C CB  . VAL A 1 1079 ? 144.090 166.885 206.781 1.00 114.51 ? 1201 VAL A CB  1 
ATOM   7554 C CG1 . VAL A 1 1079 ? 143.122 166.819 207.957 1.00 120.89 ? 1201 VAL A CG1 1 
ATOM   7555 C CG2 . VAL A 1 1079 ? 143.352 166.631 205.480 1.00 112.71 ? 1201 VAL A CG2 1 
ATOM   7556 N N   . LEU A 1 1080 ? 145.175 169.429 208.795 1.00 130.49 ? 1202 LEU A N   1 
ATOM   7557 C CA  . LEU A 1 1080 ? 145.915 169.882 209.968 1.00 134.84 ? 1202 LEU A CA  1 
ATOM   7558 C C   . LEU A 1 1080 ? 145.973 168.789 211.033 1.00 136.36 ? 1202 LEU A C   1 
ATOM   7559 O O   . LEU A 1 1080 ? 144.990 168.057 211.213 1.00 137.03 ? 1202 LEU A O   1 
ATOM   7560 C CB  . LEU A 1 1080 ? 145.266 171.141 210.544 1.00 137.17 ? 1202 LEU A CB  1 
ATOM   7561 C CG  . LEU A 1 1080 ? 145.513 172.479 209.842 1.00 134.39 ? 1202 LEU A CG  1 
ATOM   7562 C CD1 . LEU A 1 1080 ? 144.969 173.619 210.686 1.00 130.13 ? 1202 LEU A CD1 1 
ATOM   7563 C CD2 . LEU A 1 1080 ? 146.993 172.697 209.548 1.00 130.82 ? 1202 LEU A CD2 1 
ATOM   7564 N N   . PRO A 1 1081 ? 147.109 168.623 211.730 1.00 137.83 ? 1203 PRO A N   1 
ATOM   7565 C CA  . PRO A 1 1081 ? 147.224 167.512 212.691 1.00 140.75 ? 1203 PRO A CA  1 
ATOM   7566 C C   . PRO A 1 1081 ? 146.463 167.732 213.989 1.00 142.62 ? 1203 PRO A C   1 
ATOM   7567 O O   . PRO A 1 1081 ? 146.163 166.761 214.695 1.00 142.87 ? 1203 PRO A O   1 
ATOM   7568 C CB  . PRO A 1 1081 ? 148.739 167.428 212.937 1.00 137.37 ? 1203 PRO A CB  1 
ATOM   7569 C CG  . PRO A 1 1081 ? 149.356 168.100 211.749 1.00 132.05 ? 1203 PRO A CG  1 
ATOM   7570 C CD  . PRO A 1 1081 ? 148.425 169.229 211.462 1.00 134.10 ? 1203 PRO A CD  1 
ATOM   7571 N N   . ASP A 1 1082 ? 146.139 168.981 214.325 1.00 143.18 ? 1204 ASP A N   1 
ATOM   7572 C CA  . ASP A 1 1082 ? 145.357 169.241 215.528 1.00 145.70 ? 1204 ASP A CA  1 
ATOM   7573 C C   . ASP A 1 1082 ? 143.861 169.119 215.282 1.00 143.21 ? 1204 ASP A C   1 
ATOM   7574 O O   . ASP A 1 1082 ? 143.085 169.123 216.243 1.00 144.11 ? 1204 ASP A O   1 
ATOM   7575 C CB  . ASP A 1 1082 ? 145.681 170.631 216.076 1.00 146.97 ? 1204 ASP A CB  1 
ATOM   7576 C CG  . ASP A 1 1082 ? 147.085 170.723 216.637 1.00 150.08 ? 1204 ASP A CG  1 
ATOM   7577 O OD1 . ASP A 1 1082 ? 147.604 169.693 217.113 1.00 150.07 ? 1204 ASP A OD1 1 
ATOM   7578 O OD2 . ASP A 1 1082 ? 147.668 171.827 216.604 1.00 150.61 ? 1204 ASP A OD2 1 
ATOM   7579 N N   . SER A 1 1083 ? 143.438 169.010 214.022 1.00 141.74 ? 1205 SER A N   1 
ATOM   7580 C CA  . SER A 1 1083 ? 142.011 168.977 213.724 1.00 145.24 ? 1205 SER A CA  1 
ATOM   7581 C C   . SER A 1 1083 ? 141.466 167.556 213.742 1.00 147.12 ? 1205 SER A C   1 
ATOM   7582 O O   . SER A 1 1083 ? 140.248 167.351 213.680 1.00 145.75 ? 1205 SER A O   1 
ATOM   7583 C CB  . SER A 1 1083 ? 141.751 169.630 212.371 1.00 145.78 ? 1205 SER A CB  1 
ATOM   7584 O OG  . SER A 1 1083 ? 142.192 168.796 211.313 1.00 143.40 ? 1205 SER A OG  1 
ATOM   7585 N N   . VAL A 1 1084 ? 142.347 166.560 213.815 1.00 148.47 ? 1206 VAL A N   1 
ATOM   7586 C CA  . VAL A 1 1084 ? 141.914 165.167 213.846 1.00 149.37 ? 1206 VAL A CA  1 
ATOM   7587 C C   . VAL A 1 1084 ? 141.471 164.827 215.261 1.00 150.01 ? 1206 VAL A C   1 
ATOM   7588 O O   . VAL A 1 1084 ? 142.288 164.788 216.188 1.00 145.56 ? 1206 VAL A O   1 
ATOM   7589 C CB  . VAL A 1 1084 ? 143.024 164.215 213.371 1.00 147.65 ? 1206 VAL A CB  1 
ATOM   7590 C CG1 . VAL A 1 1084 ? 142.514 162.783 213.360 1.00 144.99 ? 1206 VAL A CG1 1 
ATOM   7591 C CG2 . VAL A 1 1084 ? 143.519 164.622 211.994 1.00 144.00 ? 1206 VAL A CG2 1 
ATOM   7592 N N   . ARG A 1 1085 ? 140.175 164.579 215.435 1.00 152.84 ? 1207 ARG A N   1 
ATOM   7593 C CA  . ARG A 1 1085 ? 139.605 164.326 216.747 1.00 154.58 ? 1207 ARG A CA  1 
ATOM   7594 C C   . ARG A 1 1085 ? 138.589 163.201 216.643 1.00 157.34 ? 1207 ARG A C   1 
ATOM   7595 O O   . ARG A 1 1085 ? 138.104 162.879 215.555 1.00 154.06 ? 1207 ARG A O   1 
ATOM   7596 C CB  . ARG A 1 1085 ? 138.928 165.573 217.325 1.00 156.85 ? 1207 ARG A CB  1 
ATOM   7597 C CG  . ARG A 1 1085 ? 137.831 166.134 216.438 1.00 158.23 ? 1207 ARG A CG  1 
ATOM   7598 C CD  . ARG A 1 1085 ? 137.513 167.575 216.775 1.00 160.37 ? 1207 ARG A CD  1 
ATOM   7599 N NE  . ARG A 1 1085 ? 136.574 168.149 215.821 1.00 165.72 ? 1207 ARG A NE  1 
ATOM   7600 C CZ  . ARG A 1 1085 ? 136.180 169.414 215.825 1.00 167.87 ? 1207 ARG A CZ  1 
ATOM   7601 N NH1 . ARG A 1 1085 ? 136.627 170.274 216.726 1.00 166.01 ? 1207 ARG A NH1 1 
ATOM   7602 N NH2 . ARG A 1 1085 ? 135.317 169.828 214.903 1.00 165.16 ? 1207 ARG A NH2 1 
ATOM   7603 N N   . LEU A 1 1086 ? 138.273 162.606 217.787 1.00 163.11 ? 1208 LEU A N   1 
ATOM   7604 C CA  . LEU A 1 1086 ? 137.279 161.546 217.873 1.00 166.07 ? 1208 LEU A CA  1 
ATOM   7605 C C   . LEU A 1 1086 ? 136.002 162.113 218.476 1.00 170.78 ? 1208 LEU A C   1 
ATOM   7606 O O   . LEU A 1 1086 ? 136.046 162.773 219.520 1.00 167.20 ? 1208 LEU A O   1 
ATOM   7607 C CB  . LEU A 1 1086 ? 137.794 160.375 218.709 1.00 160.37 ? 1208 LEU A CB  1 
ATOM   7608 N N   . ASP A 1 1087 ? 134.876 161.869 217.812 1.00 173.57 ? 1209 ASP A N   1 
ATOM   7609 C CA  . ASP A 1 1087 ? 133.584 162.251 218.362 1.00 175.90 ? 1209 ASP A CA  1 
ATOM   7610 C C   . ASP A 1 1087 ? 133.210 161.306 219.498 1.00 177.60 ? 1209 ASP A C   1 
ATOM   7611 O O   . ASP A 1 1087 ? 133.648 160.153 219.532 1.00 177.64 ? 1209 ASP A O   1 
ATOM   7612 C CB  . ASP A 1 1087 ? 132.513 162.228 217.271 1.00 174.71 ? 1209 ASP A CB  1 
ATOM   7613 C CG  . ASP A 1 1087 ? 131.292 163.058 217.628 1.00 176.67 ? 1209 ASP A CG  1 
ATOM   7614 O OD1 . ASP A 1 1087 ? 131.394 163.900 218.543 1.00 179.04 ? 1209 ASP A OD1 1 
ATOM   7615 O OD2 . ASP A 1 1087 ? 130.230 162.863 217.001 1.00 173.82 ? 1209 ASP A OD2 1 
ATOM   7616 N N   . ASP A 1 1088 ? 132.409 161.809 220.437 1.00 179.99 ? 1210 ASP A N   1 
ATOM   7617 C CA  . ASP A 1 1088 ? 132.033 161.024 221.605 1.00 181.51 ? 1210 ASP A CA  1 
ATOM   7618 C C   . ASP A 1 1088 ? 130.976 159.988 221.241 1.00 183.16 ? 1210 ASP A C   1 
ATOM   7619 O O   . ASP A 1 1088 ? 129.915 160.323 220.708 1.00 181.34 ? 1210 ASP A O   1 
ATOM   7620 C CB  . ASP A 1 1088 ? 131.517 161.942 222.713 1.00 179.05 ? 1210 ASP A CB  1 
ATOM   7621 N N   . GLY A 1 1089 ? 131.279 158.725 221.528 1.00 184.02 ? 1211 GLY A N   1 
ATOM   7622 C CA  . GLY A 1 1089 ? 130.375 157.639 221.201 1.00 182.44 ? 1211 GLY A CA  1 
ATOM   7623 C C   . GLY A 1 1089 ? 130.767 156.382 221.942 1.00 185.54 ? 1211 GLY A C   1 
ATOM   7624 O O   . GLY A 1 1089 ? 131.648 156.385 222.804 1.00 185.95 ? 1211 GLY A O   1 
ATOM   7625 N N   . HIS A 1 1090 ? 130.092 155.292 221.586 1.00 186.36 ? 1212 HIS A N   1 
ATOM   7626 C CA  . HIS A 1 1090 ? 130.332 154.012 222.232 1.00 186.74 ? 1212 HIS A CA  1 
ATOM   7627 C C   . HIS A 1 1090 ? 131.553 153.320 221.631 1.00 188.42 ? 1212 HIS A C   1 
ATOM   7628 O O   . HIS A 1 1090 ? 132.174 153.801 220.679 1.00 188.37 ? 1212 HIS A O   1 
ATOM   7629 C CB  . HIS A 1 1090 ? 129.105 153.110 222.108 1.00 178.73 ? 1212 HIS A CB  1 
ATOM   7630 N N   . TRP A 1 1091 ? 131.895 152.165 222.210 1.00 186.34 ? 1213 TRP A N   1 
ATOM   7631 C CA  . TRP A 1 1091 ? 133.046 151.405 221.735 1.00 184.20 ? 1213 TRP A CA  1 
ATOM   7632 C C   . TRP A 1 1091 ? 132.728 150.660 220.443 1.00 186.33 ? 1213 TRP A C   1 
ATOM   7633 O O   . TRP A 1 1091 ? 133.633 150.345 219.662 1.00 184.82 ? 1213 TRP A O   1 
ATOM   7634 C CB  . TRP A 1 1091 ? 133.512 150.428 222.816 1.00 177.77 ? 1213 TRP A CB  1 
ATOM   7635 N N   . ASP A 1 1092 ? 131.448 150.361 220.210 1.00 186.62 ? 1214 ASP A N   1 
ATOM   7636 C CA  . ASP A 1 1092 ? 131.058 149.683 218.977 1.00 183.15 ? 1214 ASP A CA  1 
ATOM   7637 C C   . ASP A 1 1092 ? 131.058 150.642 217.792 1.00 185.34 ? 1214 ASP A C   1 
ATOM   7638 O O   . ASP A 1 1092 ? 131.414 150.258 216.673 1.00 184.04 ? 1214 ASP A O   1 
ATOM   7639 C CB  . ASP A 1 1092 ? 129.682 149.040 219.145 1.00 174.59 ? 1214 ASP A CB  1 
ATOM   7640 N N   . ASP A 1 1093 ? 130.667 151.895 218.018 1.00 186.18 ? 1215 ASP A N   1 
ATOM   7641 C CA  . ASP A 1 1093 ? 130.570 152.896 216.961 1.00 185.19 ? 1215 ASP A CA  1 
ATOM   7642 C C   . ASP A 1 1093 ? 131.375 154.124 217.370 1.00 183.16 ? 1215 ASP A C   1 
ATOM   7643 O O   . ASP A 1 1093 ? 130.916 154.928 218.190 1.00 180.71 ? 1215 ASP A O   1 
ATOM   7644 C CB  . ASP A 1 1093 ? 129.112 153.264 216.688 1.00 183.21 ? 1215 ASP A CB  1 
ATOM   7645 C CG  . ASP A 1 1093 ? 128.878 153.716 215.256 1.00 178.47 ? 1215 ASP A CG  1 
ATOM   7646 O OD1 . ASP A 1 1093 ? 129.859 154.042 214.556 1.00 177.30 ? 1215 ASP A OD1 1 
ATOM   7647 O OD2 . ASP A 1 1093 ? 127.704 153.746 214.830 1.00 172.87 ? 1215 ASP A OD2 1 
ATOM   7648 N N   . PHE A 1 1094 ? 132.566 154.268 216.799 1.00 182.95 ? 1216 PHE A N   1 
ATOM   7649 C CA  . PHE A 1 1094 ? 133.377 155.466 216.950 1.00 181.49 ? 1216 PHE A CA  1 
ATOM   7650 C C   . PHE A 1 1094 ? 133.289 156.304 215.683 1.00 179.86 ? 1216 PHE A C   1 
ATOM   7651 O O   . PHE A 1 1094 ? 132.963 155.789 214.609 1.00 180.04 ? 1216 PHE A O   1 
ATOM   7652 C CB  . PHE A 1 1094 ? 134.841 155.122 217.241 1.00 178.90 ? 1216 PHE A CB  1 
ATOM   7653 C CG  . PHE A 1 1094 ? 135.197 155.154 218.699 1.00 184.61 ? 1216 PHE A CG  1 
ATOM   7654 C CD1 . PHE A 1 1094 ? 135.521 156.365 219.316 1.00 184.22 ? 1216 PHE A CD1 1 
ATOM   7655 C CD2 . PHE A 1 1094 ? 135.219 153.977 219.451 1.00 184.76 ? 1216 PHE A CD2 1 
ATOM   7656 C CE1 . PHE A 1 1094 ? 135.857 156.408 220.674 1.00 182.45 ? 1216 PHE A CE1 1 
ATOM   7657 C CE2 . PHE A 1 1094 ? 135.553 154.004 220.808 1.00 180.49 ? 1216 PHE A CE2 1 
ATOM   7658 C CZ  . PHE A 1 1094 ? 135.872 155.223 221.417 1.00 178.92 ? 1216 PHE A CZ  1 
ATOM   7659 N N   . HIS A 1 1095 ? 133.575 157.594 215.815 1.00 176.41 ? 1217 HIS A N   1 
ATOM   7660 C CA  . HIS A 1 1095 ? 133.610 158.519 214.689 1.00 171.68 ? 1217 HIS A CA  1 
ATOM   7661 C C   . HIS A 1 1095 ? 134.826 159.416 214.832 1.00 167.76 ? 1217 HIS A C   1 
ATOM   7662 O O   . HIS A 1 1095 ? 134.902 160.217 215.770 1.00 168.94 ? 1217 HIS A O   1 
ATOM   7663 C CB  . HIS A 1 1095 ? 132.332 159.358 214.619 1.00 170.86 ? 1217 HIS A CB  1 
ATOM   7664 C CG  . HIS A 1 1095 ? 131.225 158.712 213.846 1.00 171.94 ? 1217 HIS A CG  1 
ATOM   7665 N ND1 . HIS A 1 1095 ? 130.405 157.745 214.386 1.00 173.96 ? 1217 HIS A ND1 1 
ATOM   7666 C CD2 . HIS A 1 1095 ? 130.802 158.896 212.573 1.00 167.21 ? 1217 HIS A CD2 1 
ATOM   7667 C CE1 . HIS A 1 1095 ? 129.525 157.360 213.479 1.00 170.24 ? 1217 HIS A CE1 1 
ATOM   7668 N NE2 . HIS A 1 1095 ? 129.744 158.044 212.371 1.00 167.62 ? 1217 HIS A NE2 1 
ATOM   7669 N N   . VAL A 1 1096 ? 135.774 159.283 213.910 1.00 162.34 ? 1218 VAL A N   1 
ATOM   7670 C CA  . VAL A 1 1096 ? 136.922 160.177 213.839 1.00 157.97 ? 1218 VAL A CA  1 
ATOM   7671 C C   . VAL A 1 1096 ? 136.670 161.198 212.728 1.00 153.74 ? 1218 VAL A C   1 
ATOM   7672 O O   . VAL A 1 1096 ? 136.194 160.855 211.636 1.00 151.20 ? 1218 VAL A O   1 
ATOM   7673 C CB  . VAL A 1 1096 ? 138.246 159.388 213.688 1.00 157.14 ? 1218 VAL A CB  1 
ATOM   7674 C CG1 . VAL A 1 1096 ? 138.283 158.426 212.487 1.00 152.84 ? 1218 VAL A CG1 1 
ATOM   7675 C CG2 . VAL A 1 1096 ? 139.460 160.318 213.672 1.00 154.29 ? 1218 VAL A CG2 1 
ATOM   7676 N N   . ARG A 1 1097 ? 136.852 162.476 213.059 1.00 153.46 ? 1219 ARG A N   1 
ATOM   7677 C CA  . ARG A 1 1097 ? 136.562 163.583 212.160 1.00 149.26 ? 1219 ARG A CA  1 
ATOM   7678 C C   . ARG A 1 1097 ? 137.789 164.468 212.041 1.00 147.84 ? 1219 ARG A C   1 
ATOM   7679 O O   . ARG A 1 1097 ? 138.667 164.450 212.910 1.00 148.30 ? 1219 ARG A O   1 
ATOM   7680 C CB  . ARG A 1 1097 ? 135.366 164.425 212.645 1.00 150.91 ? 1219 ARG A CB  1 
ATOM   7681 C CG  . ARG A 1 1097 ? 134.076 163.648 212.858 1.00 155.20 ? 1219 ARG A CG  1 
ATOM   7682 C CD  . ARG A 1 1097 ? 132.950 164.540 213.338 1.00 154.62 ? 1219 ARG A CD  1 
ATOM   7683 N NE  . ARG A 1 1097 ? 131.765 163.759 213.665 1.00 161.63 ? 1219 ARG A NE  1 
ATOM   7684 C CZ  . ARG A 1 1097 ? 130.765 163.529 212.823 1.00 162.24 ? 1219 ARG A CZ  1 
ATOM   7685 N NH1 . ARG A 1 1097 ? 130.773 164.015 211.593 1.00 155.50 ? 1219 ARG A NH1 1 
ATOM   7686 N NH2 . ARG A 1 1097 ? 129.736 162.791 213.225 1.00 163.88 ? 1219 ARG A NH2 1 
ATOM   7687 N N   . TRP A 1 1098 ? 137.847 165.240 210.960 1.00 142.91 ? 1220 TRP A N   1 
ATOM   7688 C CA  . TRP A 1 1098 ? 138.968 166.125 210.694 1.00 139.22 ? 1220 TRP A CA  1 
ATOM   7689 C C   . TRP A 1 1098 ? 138.467 167.345 209.935 1.00 136.62 ? 1220 TRP A C   1 
ATOM   7690 O O   . TRP A 1 1098 ? 137.287 167.426 209.579 1.00 134.54 ? 1220 TRP A O   1 
ATOM   7691 C CB  . TRP A 1 1098 ? 140.075 165.370 209.927 1.00 136.77 ? 1220 TRP A CB  1 
ATOM   7692 C CG  . TRP A 1 1098 ? 139.635 164.664 208.661 1.00 132.21 ? 1220 TRP A CG  1 
ATOM   7693 C CD1 . TRP A 1 1098 ? 139.368 165.231 207.446 1.00 129.44 ? 1220 TRP A CD1 1 
ATOM   7694 C CD2 . TRP A 1 1098 ? 139.328 163.272 208.524 1.00 132.86 ? 1220 TRP A CD2 1 
ATOM   7695 N NE1 . TRP A 1 1098 ? 138.970 164.273 206.550 1.00 129.45 ? 1220 TRP A NE1 1 
ATOM   7696 C CE2 . TRP A 1 1098 ? 138.928 163.062 207.186 1.00 129.76 ? 1220 TRP A CE2 1 
ATOM   7697 C CE3 . TRP A 1 1098 ? 139.364 162.179 209.399 1.00 138.62 ? 1220 TRP A CE3 1 
ATOM   7698 C CZ2 . TRP A 1 1098 ? 138.571 161.802 206.702 1.00 130.75 ? 1220 TRP A CZ2 1 
ATOM   7699 C CZ3 . TRP A 1 1098 ? 139.014 160.925 208.914 1.00 138.42 ? 1220 TRP A CZ3 1 
ATOM   7700 C CH2 . TRP A 1 1098 ? 138.622 160.749 207.577 1.00 134.66 ? 1220 TRP A CH2 1 
ATOM   7701 N N   . GLN A 1 1099 ? 139.364 168.302 209.720 1.00 136.93 ? 1221 GLN A N   1 
ATOM   7702 C CA  . GLN A 1 1099 ? 139.023 169.487 208.943 1.00 134.86 ? 1221 GLN A CA  1 
ATOM   7703 C C   . GLN A 1 1099 ? 138.936 169.115 207.465 1.00 132.98 ? 1221 GLN A C   1 
ATOM   7704 O O   . GLN A 1 1099 ? 139.798 168.370 206.975 1.00 133.16 ? 1221 GLN A O   1 
ATOM   7705 C CB  . GLN A 1 1099 ? 140.062 170.587 209.158 1.00 136.61 ? 1221 GLN A CB  1 
ATOM   7706 C CG  . GLN A 1 1099 ? 139.747 171.912 208.488 1.00 141.08 ? 1221 GLN A CG  1 
ATOM   7707 C CD  . GLN A 1 1099 ? 140.770 172.982 208.812 1.00 145.90 ? 1221 GLN A CD  1 
ATOM   7708 O OE1 . GLN A 1 1099 ? 141.754 172.727 209.506 1.00 142.86 ? 1221 GLN A OE1 1 
ATOM   7709 N NE2 . GLN A 1 1099 ? 140.543 174.190 208.308 1.00 143.71 ? 1221 GLN A NE2 1 
ATOM   7710 N N   . PRO A 1 1100 ? 137.900 169.556 206.742 1.00 131.78 ? 1222 PRO A N   1 
ATOM   7711 C CA  . PRO A 1 1100 ? 137.783 169.201 205.320 1.00 129.56 ? 1222 PRO A CA  1 
ATOM   7712 C C   . PRO A 1 1100 ? 138.786 169.954 204.457 1.00 129.20 ? 1222 PRO A C   1 
ATOM   7713 O O   . PRO A 1 1100 ? 138.760 171.183 204.369 1.00 131.14 ? 1222 PRO A O   1 
ATOM   7714 C CB  . PRO A 1 1100 ? 136.342 169.596 204.972 1.00 128.91 ? 1222 PRO A CB  1 
ATOM   7715 C CG  . PRO A 1 1100 ? 135.634 169.682 206.271 1.00 130.26 ? 1222 PRO A CG  1 
ATOM   7716 C CD  . PRO A 1 1100 ? 136.652 170.157 207.248 1.00 132.72 ? 1222 PRO A CD  1 
ATOM   7717 N N   . SER A 1 1101 ? 139.686 169.196 203.841 1.00 128.26 ? 1223 SER A N   1 
ATOM   7718 C CA  . SER A 1 1101 ? 140.701 169.736 202.952 1.00 124.12 ? 1223 SER A CA  1 
ATOM   7719 C C   . SER A 1 1101 ? 140.073 170.180 201.638 1.00 122.78 ? 1223 SER A C   1 
ATOM   7720 O O   . SER A 1 1101 ? 139.157 169.549 201.107 1.00 121.45 ? 1223 SER A O   1 
ATOM   7721 C CB  . SER A 1 1101 ? 141.791 168.699 202.688 1.00 118.61 ? 1223 SER A CB  1 
ATOM   7722 O OG  . SER A 1 1101 ? 142.487 168.986 201.489 1.00 116.05 ? 1223 SER A OG  1 
ATOM   7723 N N   . THR A 1 1102 ? 140.582 171.290 201.116 1.00 121.09 ? 1224 THR A N   1 
ATOM   7724 C CA  . THR A 1 1102 ? 140.050 171.878 199.901 1.00 123.06 ? 1224 THR A CA  1 
ATOM   7725 C C   . THR A 1 1102 ? 141.208 172.227 198.980 1.00 121.02 ? 1224 THR A C   1 
ATOM   7726 O O   . THR A 1 1102 ? 142.374 171.989 199.294 1.00 118.77 ? 1224 THR A O   1 
ATOM   7727 C CB  . THR A 1 1102 ? 139.193 173.112 200.209 1.00 126.07 ? 1224 THR A CB  1 
ATOM   7728 O OG1 . THR A 1 1102 ? 138.600 173.603 199.001 1.00 128.00 ? 1224 THR A OG1 1 
ATOM   7729 C CG2 . THR A 1 1102 ? 140.033 174.210 200.859 1.00 121.24 ? 1224 THR A CG2 1 
ATOM   7730 N N   . SER A 1 1103 ? 140.870 172.774 197.821 1.00 117.23 ? 1225 SER A N   1 
ATOM   7731 C CA  . SER A 1 1103 ? 141.862 173.258 196.879 1.00 112.27 ? 1225 SER A CA  1 
ATOM   7732 C C   . SER A 1 1103 ? 141.507 174.685 196.484 1.00 116.08 ? 1225 SER A C   1 
ATOM   7733 O O   . SER A 1 1103 ? 140.610 175.301 197.066 1.00 118.98 ? 1225 SER A O   1 
ATOM   7734 C CB  . SER A 1 1103 ? 141.949 172.340 195.660 1.00 104.03 ? 1225 SER A CB  1 
ATOM   7735 O OG  . SER A 1 1103 ? 140.665 172.077 195.129 1.00 108.68 ? 1225 SER A OG  1 
ATOM   7736 N N   . GLY A 1 1104 ? 142.251 175.219 195.511 1.00 113.65 ? 1226 GLY A N   1 
ATOM   7737 C CA  . GLY A 1 1104 ? 141.959 176.558 195.019 1.00 111.86 ? 1226 GLY A CA  1 
ATOM   7738 C C   . GLY A 1 1104 ? 140.696 176.596 194.181 1.00 116.35 ? 1226 GLY A C   1 
ATOM   7739 O O   . GLY A 1 1104 ? 139.761 177.342 194.475 1.00 124.67 ? 1226 GLY A O   1 
ATOM   7740 N N   . GLY A 1 1105 ? 140.649 175.781 193.133 1.00 112.19 ? 1227 GLY A N   1 
ATOM   7741 C CA  . GLY A 1 1105 ? 139.377 175.464 192.521 1.00 114.80 ? 1227 GLY A CA  1 
ATOM   7742 C C   . GLY A 1 1105 ? 138.637 174.460 193.384 1.00 118.12 ? 1227 GLY A C   1 
ATOM   7743 O O   . GLY A 1 1105 ? 139.218 173.506 193.899 1.00 123.07 ? 1227 GLY A O   1 
ATOM   7744 N N   . ASN A 1 1106 ? 137.336 174.686 193.556 1.00 122.60 ? 1228 ASN A N   1 
ATOM   7745 C CA  . ASN A 1 1106 ? 136.545 173.895 194.496 1.00 126.43 ? 1228 ASN A CA  1 
ATOM   7746 C C   . ASN A 1 1106 ? 136.145 172.551 193.880 1.00 124.63 ? 1228 ASN A C   1 
ATOM   7747 O O   . ASN A 1 1106 ? 135.027 172.345 193.407 1.00 124.32 ? 1228 ASN A O   1 
ATOM   7748 C CB  . ASN A 1 1106 ? 135.335 174.697 194.955 1.00 135.04 ? 1228 ASN A CB  1 
ATOM   7749 C CG  . ASN A 1 1106 ? 135.731 175.987 195.646 1.00 142.16 ? 1228 ASN A CG  1 
ATOM   7750 O OD1 . ASN A 1 1106 ? 136.507 175.974 196.602 1.00 138.21 ? 1228 ASN A OD1 1 
ATOM   7751 N ND2 . ASN A 1 1106 ? 135.209 177.110 195.163 1.00 149.42 ? 1228 ASN A ND2 1 
ATOM   7752 N N   . HIS A 1 1107 ? 137.102 171.625 193.897 1.00 119.17 ? 1229 HIS A N   1 
ATOM   7753 C CA  . HIS A 1 1107 ? 136.895 170.283 193.385 1.00 115.51 ? 1229 HIS A CA  1 
ATOM   7754 C C   . HIS A 1 1107 ? 136.554 169.326 194.518 1.00 115.25 ? 1229 HIS A C   1 
ATOM   7755 O O   . HIS A 1 1107 ? 136.691 169.644 195.702 1.00 115.29 ? 1229 HIS A O   1 
ATOM   7756 C CB  . HIS A 1 1107 ? 138.136 169.782 192.649 1.00 109.55 ? 1229 HIS A CB  1 
ATOM   7757 C CG  . HIS A 1 1107 ? 138.549 170.641 191.496 1.00 106.60 ? 1229 HIS A CG  1 
ATOM   7758 N ND1 . HIS A 1 1107 ? 137.859 170.670 190.305 1.00 106.47 ? 1229 HIS A ND1 1 
ATOM   7759 C CD2 . HIS A 1 1107 ? 139.587 171.496 191.351 1.00 102.04 ? 1229 HIS A CD2 1 
ATOM   7760 C CE1 . HIS A 1 1107 ? 138.453 171.509 189.475 1.00 105.30 ? 1229 HIS A CE1 1 
ATOM   7761 N NE2 . HIS A 1 1107 ? 139.505 172.023 190.087 1.00 101.27 ? 1229 HIS A NE2 1 
ATOM   7762 N N   . SER A 1 1108 ? 136.108 168.132 194.137 1.00 116.99 ? 1230 SER A N   1 
ATOM   7763 C CA  . SER A 1 1108 ? 135.777 167.111 195.118 1.00 117.78 ? 1230 SER A CA  1 
ATOM   7764 C C   . SER A 1 1108 ? 137.047 166.454 195.639 1.00 113.72 ? 1230 SER A C   1 
ATOM   7765 O O   . SER A 1 1108 ? 137.841 165.909 194.869 1.00 111.00 ? 1230 SER A O   1 
ATOM   7766 C CB  . SER A 1 1108 ? 134.854 166.066 194.495 1.00 115.98 ? 1230 SER A CB  1 
ATOM   7767 O OG  . SER A 1 1108 ? 135.455 165.477 193.357 1.00 119.42 ? 1230 SER A OG  1 
ATOM   7768 N N   . VAL A 1 1109 ? 137.234 166.507 196.954 1.00 110.04 ? 1231 VAL A N   1 
ATOM   7769 C CA  . VAL A 1 1109 ? 138.417 165.964 197.608 1.00 105.07 ? 1231 VAL A CA  1 
ATOM   7770 C C   . VAL A 1 1109 ? 138.018 164.675 198.311 1.00 108.26 ? 1231 VAL A C   1 
ATOM   7771 O O   . VAL A 1 1109 ? 137.174 164.687 199.215 1.00 115.59 ? 1231 VAL A O   1 
ATOM   7772 C CB  . VAL A 1 1109 ? 139.032 166.969 198.593 1.00 103.64 ? 1231 VAL A CB  1 
ATOM   7773 C CG1 . VAL A 1 1109 ? 140.156 166.326 199.383 1.00 103.25 ? 1231 VAL A CG1 1 
ATOM   7774 C CG2 . VAL A 1 1109 ? 139.540 168.187 197.847 1.00 110.44 ? 1231 VAL A CG2 1 
ATOM   7775 N N   . SER A 1 1110 ? 138.615 163.567 197.891 1.00 104.56 ? 1232 SER A N   1 
ATOM   7776 C CA  . SER A 1 1110 ? 138.398 162.269 198.509 1.00 106.53 ? 1232 SER A CA  1 
ATOM   7777 C C   . SER A 1 1110 ? 139.542 161.947 199.461 1.00 106.09 ? 1232 SER A C   1 
ATOM   7778 O O   . SER A 1 1110 ? 140.613 162.554 199.408 1.00 108.17 ? 1232 SER A O   1 
ATOM   7779 C CB  . SER A 1 1110 ? 138.270 161.176 197.449 1.00 109.82 ? 1232 SER A CB  1 
ATOM   7780 O OG  . SER A 1 1110 ? 137.251 161.494 196.519 1.00 111.30 ? 1232 SER A OG  1 
ATOM   7781 N N   . TYR A 1 1111 ? 139.301 160.980 200.341 1.00 109.16 ? 1233 TYR A N   1 
ATOM   7782 C CA  . TYR A 1 1111 ? 140.240 160.640 201.400 1.00 108.11 ? 1233 TYR A CA  1 
ATOM   7783 C C   . TYR A 1 1111 ? 140.497 159.143 201.408 1.00 111.85 ? 1233 TYR A C   1 
ATOM   7784 O O   . TYR A 1 1111 ? 139.553 158.348 201.393 1.00 122.07 ? 1233 TYR A O   1 
ATOM   7785 C CB  . TYR A 1 1111 ? 139.710 161.080 202.767 1.00 107.89 ? 1233 TYR A CB  1 
ATOM   7786 C CG  . TYR A 1 1111 ? 139.496 162.568 202.900 1.00 111.43 ? 1233 TYR A CG  1 
ATOM   7787 C CD1 . TYR A 1 1111 ? 140.558 163.411 203.242 1.00 111.31 ? 1233 TYR A CD1 1 
ATOM   7788 C CD2 . TYR A 1 1111 ? 138.232 163.129 202.689 1.00 116.83 ? 1233 TYR A CD2 1 
ATOM   7789 C CE1 . TYR A 1 1111 ? 140.368 164.786 203.370 1.00 110.19 ? 1233 TYR A CE1 1 
ATOM   7790 C CE2 . TYR A 1 1111 ? 138.028 164.501 202.812 1.00 117.22 ? 1233 TYR A CE2 1 
ATOM   7791 C CZ  . TYR A 1 1111 ? 139.102 165.317 203.153 1.00 115.89 ? 1233 TYR A CZ  1 
ATOM   7792 O OH  . TYR A 1 1111 ? 138.908 166.671 203.277 1.00 124.17 ? 1233 TYR A OH  1 
ATOM   7793 N N   . ARG A 1 1112 ? 141.770 158.764 201.437 1.00 106.72 ? 1234 ARG A N   1 
ATOM   7794 C CA  . ARG A 1 1112 ? 142.182 157.386 201.667 1.00 105.25 ? 1234 ARG A CA  1 
ATOM   7795 C C   . ARG A 1 1112 ? 142.773 157.290 203.066 1.00 105.48 ? 1234 ARG A C   1 
ATOM   7796 O O   . ARG A 1 1112 ? 143.625 158.099 203.445 1.00 110.30 ? 1234 ARG A O   1 
ATOM   7797 C CB  . ARG A 1 1112 ? 143.160 156.914 200.589 1.00 105.77 ? 1234 ARG A CB  1 
ATOM   7798 C CG  . ARG A 1 1112 ? 142.478 156.797 199.234 1.00 108.64 ? 1234 ARG A CG  1 
ATOM   7799 C CD  . ARG A 1 1112 ? 143.372 156.340 198.092 1.00 109.59 ? 1234 ARG A CD  1 
ATOM   7800 N NE  . ARG A 1 1112 ? 142.590 156.287 196.863 1.00 116.49 ? 1234 ARG A NE  1 
ATOM   7801 C CZ  . ARG A 1 1112 ? 143.057 155.989 195.658 1.00 118.58 ? 1234 ARG A CZ  1 
ATOM   7802 N NH1 . ARG A 1 1112 ? 144.342 155.784 195.445 1.00 119.42 ? 1234 ARG A NH1 1 
ATOM   7803 N NH2 . ARG A 1 1112 ? 142.212 155.919 194.636 1.00 116.49 ? 1234 ARG A NH2 1 
ATOM   7804 N N   . LEU A 1 1113 ? 142.308 156.303 203.824 1.00 110.03 ? 1235 LEU A N   1 
ATOM   7805 C CA  . LEU A 1 1113 ? 142.463 156.244 205.270 1.00 113.61 ? 1235 LEU A CA  1 
ATOM   7806 C C   . LEU A 1 1113 ? 143.142 154.943 205.677 1.00 120.85 ? 1235 LEU A C   1 
ATOM   7807 O O   . LEU A 1 1113 ? 142.923 153.900 205.056 1.00 124.95 ? 1235 LEU A O   1 
ATOM   7808 C CB  . LEU A 1 1113 ? 141.088 156.371 205.934 1.00 117.84 ? 1235 LEU A CB  1 
ATOM   7809 C CG  . LEU A 1 1113 ? 140.876 156.344 207.446 1.00 118.68 ? 1235 LEU A CG  1 
ATOM   7810 C CD1 . LEU A 1 1113 ? 141.600 157.456 208.133 1.00 121.27 ? 1235 LEU A CD1 1 
ATOM   7811 C CD2 . LEU A 1 1113 ? 139.394 156.418 207.757 1.00 117.62 ? 1235 LEU A CD2 1 
ATOM   7812 N N   . LEU A 1 1114 ? 143.977 155.012 206.711 1.00 119.44 ? 1236 LEU A N   1 
ATOM   7813 C CA  . LEU A 1 1114 ? 144.683 153.852 207.240 1.00 122.25 ? 1236 LEU A CA  1 
ATOM   7814 C C   . LEU A 1 1114 ? 144.474 153.797 208.746 1.00 128.76 ? 1236 LEU A C   1 
ATOM   7815 O O   . LEU A 1 1114 ? 144.674 154.800 209.438 1.00 131.82 ? 1236 LEU A O   1 
ATOM   7816 C CB  . LEU A 1 1114 ? 146.173 153.927 206.907 1.00 120.73 ? 1236 LEU A CB  1 
ATOM   7817 C CG  . LEU A 1 1114 ? 147.046 152.794 207.440 1.00 123.33 ? 1236 LEU A CG  1 
ATOM   7818 C CD1 . LEU A 1 1114 ? 146.669 151.467 206.798 1.00 123.67 ? 1236 LEU A CD1 1 
ATOM   7819 C CD2 . LEU A 1 1114 ? 148.513 153.111 207.243 1.00 119.05 ? 1236 LEU A CD2 1 
ATOM   7820 N N   . LEU A 1 1115 ? 144.068 152.633 209.250 1.00 133.18 ? 1237 LEU A N   1 
ATOM   7821 C CA  . LEU A 1 1115 ? 143.865 152.417 210.677 1.00 134.19 ? 1237 LEU A CA  1 
ATOM   7822 C C   . LEU A 1 1115 ? 144.910 151.410 211.140 1.00 136.90 ? 1237 LEU A C   1 
ATOM   7823 O O   . LEU A 1 1115 ? 144.907 150.264 210.681 1.00 142.77 ? 1237 LEU A O   1 
ATOM   7824 C CB  . LEU A 1 1115 ? 142.465 151.868 210.973 1.00 137.37 ? 1237 LEU A CB  1 
ATOM   7825 C CG  . LEU A 1 1115 ? 141.173 152.694 211.096 1.00 140.27 ? 1237 LEU A CG  1 
ATOM   7826 C CD1 . LEU A 1 1115 ? 141.196 153.670 212.247 1.00 142.96 ? 1237 LEU A CD1 1 
ATOM   7827 C CD2 . LEU A 1 1115 ? 140.752 153.375 209.806 1.00 135.25 ? 1237 LEU A CD2 1 
ATOM   7828 N N   . GLU A 1 1116 ? 145.800 151.825 212.038 1.00 136.57 ? 1238 GLU A N   1 
ATOM   7829 C CA  . GLU A 1 1116 ? 146.815 150.930 212.596 1.00 143.14 ? 1238 GLU A CA  1 
ATOM   7830 C C   . GLU A 1 1116 ? 146.607 150.813 214.101 1.00 148.73 ? 1238 GLU A C   1 
ATOM   7831 O O   . GLU A 1 1116 ? 147.073 151.657 214.870 1.00 151.81 ? 1238 GLU A O   1 
ATOM   7832 C CB  . GLU A 1 1116 ? 148.232 151.402 212.274 1.00 142.48 ? 1238 GLU A CB  1 
ATOM   7833 C CG  . GLU A 1 1116 ? 148.454 151.861 210.849 1.00 141.23 ? 1238 GLU A CG  1 
ATOM   7834 C CD  . GLU A 1 1116 ? 149.791 152.543 210.661 1.00 146.18 ? 1238 GLU A CD  1 
ATOM   7835 O OE1 . GLU A 1 1116 ? 149.808 153.751 210.346 1.00 144.22 ? 1238 GLU A OE1 1 
ATOM   7836 O OE2 . GLU A 1 1116 ? 150.826 151.871 210.842 1.00 150.09 ? 1238 GLU A OE2 1 
ATOM   7837 N N   . PHE A 1 1117 ? 145.907 149.760 214.514 1.00 150.60 ? 1239 PHE A N   1 
ATOM   7838 C CA  . PHE A 1 1117 ? 145.709 149.437 215.923 1.00 150.97 ? 1239 PHE A CA  1 
ATOM   7839 C C   . PHE A 1 1117 ? 146.094 147.977 216.156 1.00 152.78 ? 1239 PHE A C   1 
ATOM   7840 O O   . PHE A 1 1117 ? 145.668 147.087 215.413 1.00 155.14 ? 1239 PHE A O   1 
ATOM   7841 C CB  . PHE A 1 1117 ? 144.277 149.775 216.370 1.00 153.90 ? 1239 PHE A CB  1 
ATOM   7842 C CG  . PHE A 1 1117 ? 143.169 148.991 215.676 1.00 157.43 ? 1239 PHE A CG  1 
ATOM   7843 C CD1 . PHE A 1 1117 ? 142.601 149.475 214.492 1.00 156.21 ? 1239 PHE A CD1 1 
ATOM   7844 C CD2 . PHE A 1 1117 ? 142.629 147.834 216.258 1.00 161.31 ? 1239 PHE A CD2 1 
ATOM   7845 C CE1 . PHE A 1 1117 ? 141.572 148.782 213.852 1.00 158.13 ? 1239 PHE A CE1 1 
ATOM   7846 C CE2 . PHE A 1 1117 ? 141.600 147.131 215.627 1.00 164.01 ? 1239 PHE A CE2 1 
ATOM   7847 C CZ  . PHE A 1 1117 ? 141.069 147.611 214.427 1.00 162.46 ? 1239 PHE A CZ  1 
ATOM   7848 N N   . GLY A 1 1118 ? 146.945 147.752 217.159 1.00 152.67 ? 1240 GLY A N   1 
ATOM   7849 C CA  . GLY A 1 1118 ? 147.337 146.402 217.541 1.00 154.21 ? 1240 GLY A CA  1 
ATOM   7850 C C   . GLY A 1 1118 ? 148.281 145.760 216.543 1.00 155.57 ? 1240 GLY A C   1 
ATOM   7851 O O   . GLY A 1 1118 ? 149.395 146.239 216.299 1.00 152.93 ? 1240 GLY A O   1 
ATOM   7852 N N   . GLN A 1 1119 ? 147.822 144.653 215.955 1.00 154.84 ? 1241 GLN A N   1 
ATOM   7853 C CA  . GLN A 1 1119 ? 148.551 144.032 214.856 1.00 151.97 ? 1241 GLN A CA  1 
ATOM   7854 C C   . GLN A 1 1119 ? 147.793 144.187 213.544 1.00 150.45 ? 1241 GLN A C   1 
ATOM   7855 O O   . GLN A 1 1119 ? 148.404 144.277 212.473 1.00 151.86 ? 1241 GLN A O   1 
ATOM   7856 C CB  . GLN A 1 1119 ? 148.799 142.556 215.161 1.00 152.58 ? 1241 GLN A CB  1 
ATOM   7857 C CG  . GLN A 1 1119 ? 149.697 142.312 216.362 1.00 156.89 ? 1241 GLN A CG  1 
ATOM   7858 C CD  . GLN A 1 1119 ? 151.089 142.875 216.171 1.00 158.44 ? 1241 GLN A CD  1 
ATOM   7859 O OE1 . GLN A 1 1119 ? 151.467 143.858 216.806 1.00 159.26 ? 1241 GLN A OE1 1 
ATOM   7860 N NE2 . GLN A 1 1119 ? 151.864 142.251 215.290 1.00 154.23 ? 1241 GLN A NE2 1 
ATOM   7861 N N   . ARG A 1 1120 ? 146.464 144.217 213.609 1.00 148.56 ? 1242 ARG A N   1 
ATOM   7862 C CA  . ARG A 1 1120 ? 145.639 144.245 212.411 1.00 148.39 ? 1242 ARG A CA  1 
ATOM   7863 C C   . ARG A 1 1120 ? 145.561 145.651 211.823 1.00 145.79 ? 1242 ARG A C   1 
ATOM   7864 O O   . ARG A 1 1120 ? 145.908 146.643 212.469 1.00 145.75 ? 1242 ARG A O   1 
ATOM   7865 C CB  . ARG A 1 1120 ? 144.239 143.724 212.728 1.00 146.88 ? 1242 ARG A CB  1 
ATOM   7866 C CG  . ARG A 1 1120 ? 143.596 144.377 213.936 1.00 149.42 ? 1242 ARG A CG  1 
ATOM   7867 C CD  . ARG A 1 1120 ? 142.232 143.774 214.224 1.00 152.66 ? 1242 ARG A CD  1 
ATOM   7868 N NE  . ARG A 1 1120 ? 141.215 144.214 213.277 1.00 157.33 ? 1242 ARG A NE  1 
ATOM   7869 C CZ  . ARG A 1 1120 ? 140.028 143.639 213.138 1.00 161.07 ? 1242 ARG A CZ  1 
ATOM   7870 N NH1 . ARG A 1 1120 ? 139.672 142.601 213.878 1.00 160.91 ? 1242 ARG A NH1 1 
ATOM   7871 N NH2 . ARG A 1 1120 ? 139.178 144.115 212.234 1.00 159.02 ? 1242 ARG A NH2 1 
ATOM   7872 N N   . LEU A 1 1121 ? 145.111 145.723 210.572 1.00 142.90 ? 1243 LEU A N   1 
ATOM   7873 C CA  . LEU A 1 1121 ? 144.997 146.975 209.835 1.00 136.37 ? 1243 LEU A CA  1 
ATOM   7874 C C   . LEU A 1 1121 ? 143.612 147.074 209.218 1.00 135.44 ? 1243 LEU A C   1 
ATOM   7875 O O   . LEU A 1 1121 ? 142.941 146.055 209.025 1.00 136.01 ? 1243 LEU A O   1 
ATOM   7876 C CB  . LEU A 1 1121 ? 146.051 147.101 208.725 1.00 134.15 ? 1243 LEU A CB  1 
ATOM   7877 C CG  . LEU A 1 1121 ? 147.520 147.471 208.963 1.00 135.83 ? 1243 LEU A CG  1 
ATOM   7878 C CD1 . LEU A 1 1121 ? 148.356 146.381 209.626 1.00 136.95 ? 1243 LEU A CD1 1 
ATOM   7879 C CD2 . LEU A 1 1121 ? 148.124 147.868 207.632 1.00 133.62 ? 1243 LEU A CD2 1 
ATOM   7880 N N   . GLN A 1 1122 ? 143.190 148.298 208.912 1.00 135.77 ? 1244 GLN A N   1 
ATOM   7881 C CA  . GLN A 1 1122 ? 141.913 148.554 208.258 1.00 136.66 ? 1244 GLN A CA  1 
ATOM   7882 C C   . GLN A 1 1122 ? 142.066 149.770 207.356 1.00 131.41 ? 1244 GLN A C   1 
ATOM   7883 O O   . GLN A 1 1122 ? 142.553 150.815 207.796 1.00 130.63 ? 1244 GLN A O   1 
ATOM   7884 C CB  . GLN A 1 1122 ? 140.811 148.774 209.294 1.00 136.20 ? 1244 GLN A CB  1 
ATOM   7885 C CG  . GLN A 1 1122 ? 139.431 148.957 208.705 1.00 138.61 ? 1244 GLN A CG  1 
ATOM   7886 C CD  . GLN A 1 1122 ? 138.362 149.114 209.766 1.00 149.72 ? 1244 GLN A CD  1 
ATOM   7887 O OE1 . GLN A 1 1122 ? 138.654 149.124 210.963 1.00 157.67 ? 1244 GLN A OE1 1 
ATOM   7888 N NE2 . GLN A 1 1122 ? 137.115 149.239 209.333 1.00 149.44 ? 1244 GLN A NE2 1 
ATOM   7889 N N   . THR A 1 1123 ? 141.677 149.633 206.090 1.00 125.72 ? 1245 THR A N   1 
ATOM   7890 C CA  . THR A 1 1123 ? 141.750 150.722 205.124 1.00 122.16 ? 1245 THR A CA  1 
ATOM   7891 C C   . THR A 1 1123 ? 140.357 151.059 204.616 1.00 125.74 ? 1245 THR A C   1 
ATOM   7892 O O   . THR A 1 1123 ? 139.553 150.158 204.353 1.00 126.47 ? 1245 THR A O   1 
ATOM   7893 C CB  . THR A 1 1123 ? 142.653 150.373 203.935 1.00 120.48 ? 1245 THR A CB  1 
ATOM   7894 O OG1 . THR A 1 1123 ? 142.072 149.296 203.188 1.00 126.64 ? 1245 THR A OG1 1 
ATOM   7895 C CG2 . THR A 1 1123 ? 144.065 149.999 204.380 1.00 118.92 ? 1245 THR A CG2 1 
ATOM   7896 N N   . LEU A 1 1124 ? 140.073 152.353 204.477 1.00 119.80 ? 1246 LEU A N   1 
ATOM   7897 C CA  . LEU A 1 1124 ? 138.825 152.832 203.899 1.00 116.74 ? 1246 LEU A CA  1 
ATOM   7898 C C   . LEU A 1 1124 ? 139.126 153.883 202.843 1.00 115.60 ? 1246 LEU A C   1 
ATOM   7899 O O   . LEU A 1 1124 ? 140.123 154.604 202.948 1.00 117.95 ? 1246 LEU A O   1 
ATOM   7900 C CB  . LEU A 1 1124 ? 137.875 153.436 204.948 1.00 123.84 ? 1246 LEU A CB  1 
ATOM   7901 C CG  . LEU A 1 1124 ? 137.008 152.614 205.916 1.00 127.52 ? 1246 LEU A CG  1 
ATOM   7902 C CD1 . LEU A 1 1124 ? 137.787 151.921 207.021 1.00 124.60 ? 1246 LEU A CD1 1 
ATOM   7903 C CD2 . LEU A 1 1124 ? 135.913 153.489 206.505 1.00 125.07 ? 1246 LEU A CD2 1 
ATOM   7904 N N   . ASP A 1 1125 ? 138.270 153.959 201.832 1.00 118.39 ? 1247 ASP A N   1 
ATOM   7905 C CA  . ASP A 1 1125 ? 138.273 155.051 200.868 1.00 116.57 ? 1247 ASP A CA  1 
ATOM   7906 C C   . ASP A 1 1125 ? 136.999 155.852 201.111 1.00 122.53 ? 1247 ASP A C   1 
ATOM   7907 O O   . ASP A 1 1125 ? 135.900 155.290 201.107 1.00 127.98 ? 1247 ASP A O   1 
ATOM   7908 C CB  . ASP A 1 1125 ? 138.321 154.512 199.434 1.00 116.55 ? 1247 ASP A CB  1 
ATOM   7909 C CG  . ASP A 1 1125 ? 138.607 155.591 198.381 1.00 124.71 ? 1247 ASP A CG  1 
ATOM   7910 O OD1 . ASP A 1 1125 ? 138.694 155.219 197.191 1.00 127.63 ? 1247 ASP A OD1 1 
ATOM   7911 O OD2 . ASP A 1 1125 ? 138.805 156.780 198.712 1.00 123.95 ? 1247 ASP A OD2 1 
ATOM   7912 N N   . LEU A 1 1126 ? 137.148 157.157 201.324 1.00 120.05 ? 1248 LEU A N   1 
ATOM   7913 C CA  . LEU A 1 1126 ? 136.034 157.983 201.758 1.00 121.52 ? 1248 LEU A CA  1 
ATOM   7914 C C   . LEU A 1 1126 ? 135.886 159.196 200.854 1.00 126.23 ? 1248 LEU A C   1 
ATOM   7915 O O   . LEU A 1 1126 ? 136.862 159.705 200.300 1.00 126.86 ? 1248 LEU A O   1 
ATOM   7916 C CB  . LEU A 1 1126 ? 136.217 158.454 203.203 1.00 121.73 ? 1248 LEU A CB  1 
ATOM   7917 C CG  . LEU A 1 1126 ? 136.071 157.396 204.292 1.00 126.90 ? 1248 LEU A CG  1 
ATOM   7918 C CD1 . LEU A 1 1126 ? 136.519 157.965 205.622 1.00 132.22 ? 1248 LEU A CD1 1 
ATOM   7919 C CD2 . LEU A 1 1126 ? 134.636 156.906 204.372 1.00 129.23 ? 1248 LEU A CD2 1 
ATOM   7920 N N   . SER A 1 1127 ? 134.643 159.654 200.718 1.00 130.43 ? 1249 SER A N   1 
ATOM   7921 C CA  . SER A 1 1127 ? 134.331 160.920 200.072 1.00 130.47 ? 1249 SER A CA  1 
ATOM   7922 C C   . SER A 1 1127 ? 133.826 161.953 201.068 1.00 133.03 ? 1249 SER A C   1 
ATOM   7923 O O   . SER A 1 1127 ? 133.446 163.059 200.668 1.00 134.05 ? 1249 SER A O   1 
ATOM   7924 C CB  . SER A 1 1127 ? 133.302 160.710 198.960 1.00 128.04 ? 1249 SER A CB  1 
ATOM   7925 O OG  . SER A 1 1127 ? 133.169 161.874 198.165 1.00 132.14 ? 1249 SER A OG  1 
ATOM   7926 N N   . THR A 1 1128 ? 133.819 161.619 202.349 1.00 135.29 ? 1250 THR A N   1 
ATOM   7927 C CA  . THR A 1 1128 ? 133.328 162.449 203.436 1.00 134.05 ? 1250 THR A CA  1 
ATOM   7928 C C   . THR A 1 1128 ? 134.490 162.798 204.352 1.00 130.83 ? 1250 THR A C   1 
ATOM   7929 O O   . THR A 1 1128 ? 135.459 162.037 204.446 1.00 130.78 ? 1250 THR A O   1 
ATOM   7930 C CB  . THR A 1 1128 ? 132.236 161.713 204.230 1.00 137.95 ? 1250 THR A CB  1 
ATOM   7931 O OG1 . THR A 1 1128 ? 132.782 160.520 204.805 1.00 137.75 ? 1250 THR A OG1 1 
ATOM   7932 C CG2 . THR A 1 1128 ? 131.063 161.349 203.331 1.00 136.59 ? 1250 THR A CG2 1 
ATOM   7933 N N   . PRO A 1 1129 ? 134.429 163.938 205.056 1.00 130.70 ? 1251 PRO A N   1 
ATOM   7934 C CA  . PRO A 1 1129 ? 135.475 164.244 206.048 1.00 132.60 ? 1251 PRO A CA  1 
ATOM   7935 C C   . PRO A 1 1129 ? 135.296 163.569 207.405 1.00 135.82 ? 1251 PRO A C   1 
ATOM   7936 O O   . PRO A 1 1129 ? 136.054 163.881 208.330 1.00 135.55 ? 1251 PRO A O   1 
ATOM   7937 C CB  . PRO A 1 1129 ? 135.385 165.772 206.194 1.00 132.56 ? 1251 PRO A CB  1 
ATOM   7938 C CG  . PRO A 1 1129 ? 134.629 166.234 205.003 1.00 133.52 ? 1251 PRO A CG  1 
ATOM   7939 C CD  . PRO A 1 1129 ? 133.661 165.150 204.719 1.00 132.26 ? 1251 PRO A CD  1 
ATOM   7940 N N   . PHE A 1 1130 ? 134.321 162.681 207.567 1.00 141.24 ? 1252 PHE A N   1 
ATOM   7941 C CA  . PHE A 1 1130 ? 134.169 161.860 208.756 1.00 144.05 ? 1252 PHE A CA  1 
ATOM   7942 C C   . PHE A 1 1130 ? 134.328 160.399 208.362 1.00 146.17 ? 1252 PHE A C   1 
ATOM   7943 O O   . PHE A 1 1130 ? 134.226 160.044 207.184 1.00 146.10 ? 1252 PHE A O   1 
ATOM   7944 C CB  . PHE A 1 1130 ? 132.803 162.095 209.465 1.00 145.58 ? 1252 PHE A CB  1 
ATOM   7945 C CG  . PHE A 1 1130 ? 131.597 162.118 208.541 1.00 146.62 ? 1252 PHE A CG  1 
ATOM   7946 C CD1 . PHE A 1 1130 ? 131.113 163.332 208.030 1.00 146.02 ? 1252 PHE A CD1 1 
ATOM   7947 C CD2 . PHE A 1 1130 ? 130.914 160.935 208.226 1.00 145.42 ? 1252 PHE A CD2 1 
ATOM   7948 C CE1 . PHE A 1 1130 ? 130.000 163.362 207.187 1.00 142.52 ? 1252 PHE A CE1 1 
ATOM   7949 C CE2 . PHE A 1 1130 ? 129.800 160.951 207.386 1.00 144.18 ? 1252 PHE A CE2 1 
ATOM   7950 C CZ  . PHE A 1 1130 ? 129.343 162.168 206.870 1.00 142.59 ? 1252 PHE A CZ  1 
ATOM   7951 N N   . ALA A 1 1131 ? 134.587 159.553 209.352 1.00 150.75 ? 1253 ALA A N   1 
ATOM   7952 C CA  . ALA A 1 1131 ? 134.736 158.120 209.131 1.00 152.51 ? 1253 ALA A CA  1 
ATOM   7953 C C   . ALA A 1 1131 ? 133.754 157.377 210.022 1.00 162.89 ? 1253 ALA A C   1 
ATOM   7954 O O   . ALA A 1 1131 ? 133.903 157.377 211.248 1.00 163.03 ? 1253 ALA A O   1 
ATOM   7955 C CB  . ALA A 1 1131 ? 136.167 157.664 209.413 1.00 149.24 ? 1253 ALA A CB  1 
ATOM   7956 N N   . ARG A 1 1132 ? 132.752 156.754 209.407 1.00 168.05 ? 1254 ARG A N   1 
ATOM   7957 C CA  . ARG A 1 1132 ? 131.851 155.873 210.134 1.00 171.23 ? 1254 ARG A CA  1 
ATOM   7958 C C   . ARG A 1 1132 ? 132.573 154.567 210.430 1.00 173.63 ? 1254 ARG A C   1 
ATOM   7959 O O   . ARG A 1 1132 ? 132.707 153.709 209.553 1.00 171.11 ? 1254 ARG A O   1 
ATOM   7960 C CB  . ARG A 1 1132 ? 130.580 155.616 209.327 1.00 165.17 ? 1254 ARG A CB  1 
ATOM   7961 N N   . LEU A 1 1133 ? 133.032 154.417 211.668 1.00 174.06 ? 1255 LEU A N   1 
ATOM   7962 C CA  . LEU A 1 1133 ? 133.955 153.356 212.046 1.00 172.68 ? 1255 LEU A CA  1 
ATOM   7963 C C   . LEU A 1 1133 ? 133.231 152.334 212.911 1.00 178.36 ? 1255 LEU A C   1 
ATOM   7964 O O   . LEU A 1 1133 ? 132.568 152.699 213.889 1.00 179.10 ? 1255 LEU A O   1 
ATOM   7965 C CB  . LEU A 1 1133 ? 135.162 153.930 212.787 1.00 169.63 ? 1255 LEU A CB  1 
ATOM   7966 C CG  . LEU A 1 1133 ? 136.194 152.947 213.339 1.00 171.91 ? 1255 LEU A CG  1 
ATOM   7967 C CD1 . LEU A 1 1133 ? 136.786 152.096 212.225 1.00 167.18 ? 1255 LEU A CD1 1 
ATOM   7968 C CD2 . LEU A 1 1133 ? 137.286 153.688 214.090 1.00 169.81 ? 1255 LEU A CD2 1 
ATOM   7969 N N   . THR A 1 1134 ? 133.361 151.061 212.547 1.00 180.06 ? 1256 THR A N   1 
ATOM   7970 C CA  . THR A 1 1134 ? 132.854 149.954 213.340 1.00 179.09 ? 1256 THR A CA  1 
ATOM   7971 C C   . THR A 1 1134 ? 133.968 148.936 213.538 1.00 179.90 ? 1256 THR A C   1 
ATOM   7972 O O   . THR A 1 1134 ? 135.120 149.169 213.156 1.00 176.23 ? 1256 THR A O   1 
ATOM   7973 C CB  . THR A 1 1134 ? 131.641 149.284 212.678 1.00 174.49 ? 1256 THR A CB  1 
ATOM   7974 N N   . GLN A 1 1135 ? 133.601 147.813 214.160 1.00 179.57 ? 1257 GLN A N   1 
ATOM   7975 C CA  . GLN A 1 1135 ? 134.387 146.603 214.435 1.00 180.51 ? 1257 GLN A CA  1 
ATOM   7976 C C   . GLN A 1 1135 ? 135.642 146.854 215.272 1.00 182.12 ? 1257 GLN A C   1 
ATOM   7977 O O   . GLN A 1 1135 ? 136.620 146.110 215.117 1.00 179.33 ? 1257 GLN A O   1 
ATOM   7978 C CB  . GLN A 1 1135 ? 134.793 145.849 213.156 1.00 174.16 ? 1257 GLN A CB  1 
ATOM   7979 N N   . LEU A 1 1136 ? 135.661 147.864 216.136 1.00 182.12 ? 1258 LEU A N   1 
ATOM   7980 C CA  . LEU A 1 1136 ? 136.755 147.996 217.086 1.00 182.41 ? 1258 LEU A CA  1 
ATOM   7981 C C   . LEU A 1 1136 ? 136.571 146.978 218.212 1.00 184.21 ? 1258 LEU A C   1 
ATOM   7982 O O   . LEU A 1 1136 ? 135.431 146.703 218.607 1.00 181.30 ? 1258 LEU A O   1 
ATOM   7983 C CB  . LEU A 1 1136 ? 136.816 149.418 217.646 1.00 181.08 ? 1258 LEU A CB  1 
ATOM   7984 C CG  . LEU A 1 1136 ? 137.281 150.532 216.698 1.00 178.11 ? 1258 LEU A CG  1 
ATOM   7985 C CD1 . LEU A 1 1136 ? 137.504 151.824 217.468 1.00 177.45 ? 1258 LEU A CD1 1 
ATOM   7986 C CD2 . LEU A 1 1136 ? 138.545 150.149 215.933 1.00 171.66 ? 1258 LEU A CD2 1 
ATOM   7987 N N   . PRO A 1 1137 ? 137.657 146.360 218.710 1.00 186.95 ? 1259 PRO A N   1 
ATOM   7988 C CA  . PRO A 1 1137 ? 137.488 145.301 219.730 1.00 186.58 ? 1259 PRO A CA  1 
ATOM   7989 C C   . PRO A 1 1137 ? 137.091 145.790 221.120 1.00 186.02 ? 1259 PRO A C   1 
ATOM   7990 O O   . PRO A 1 1137 ? 136.114 145.280 221.686 1.00 184.96 ? 1259 PRO A O   1 
ATOM   7991 C CB  . PRO A 1 1137 ? 138.860 144.607 219.736 1.00 182.95 ? 1259 PRO A CB  1 
ATOM   7992 C CG  . PRO A 1 1137 ? 139.813 145.603 219.168 1.00 180.36 ? 1259 PRO A CG  1 
ATOM   7993 C CD  . PRO A 1 1137 ? 139.033 146.396 218.176 1.00 181.74 ? 1259 PRO A CD  1 
ATOM   7994 N N   . GLN A 1 1138 ? 137.790 146.786 221.670 1.00 185.06 ? 1260 GLN A N   1 
ATOM   7995 C CA  . GLN A 1 1138 ? 137.579 147.202 223.054 1.00 183.10 ? 1260 GLN A CA  1 
ATOM   7996 C C   . GLN A 1 1138 ? 138.065 148.625 223.294 1.00 182.04 ? 1260 GLN A C   1 
ATOM   7997 O O   . GLN A 1 1138 ? 138.398 149.347 222.349 1.00 179.14 ? 1260 GLN A O   1 
ATOM   7998 C CB  . GLN A 1 1138 ? 138.298 146.253 224.020 1.00 180.18 ? 1260 GLN A CB  1 
ATOM   7999 N N   . ALA A 1 1139 ? 138.105 149.031 224.560 1.00 183.55 ? 1261 ALA A N   1 
ATOM   8000 C CA  . ALA A 1 1139 ? 138.682 150.308 224.943 1.00 182.09 ? 1261 ALA A CA  1 
ATOM   8001 C C   . ALA A 1 1139 ? 140.173 150.146 225.229 1.00 179.81 ? 1261 ALA A C   1 
ATOM   8002 O O   . ALA A 1 1139 ? 140.738 149.054 225.081 1.00 178.52 ? 1261 ALA A O   1 
ATOM   8003 C CB  . ALA A 1 1139 ? 137.960 150.879 226.161 1.00 177.94 ? 1261 ALA A CB  1 
ATOM   8004 N N   . GLN A 1 1140 ? 140.782 151.269 225.669 1.00 178.19 ? 1262 GLN A N   1 
ATOM   8005 C CA  . GLN A 1 1140 ? 142.227 151.460 225.916 1.00 174.86 ? 1262 GLN A CA  1 
ATOM   8006 C C   . GLN A 1 1140 ? 143.073 151.105 224.694 1.00 176.59 ? 1262 GLN A C   1 
ATOM   8007 O O   . GLN A 1 1140 ? 144.104 150.435 224.798 1.00 175.90 ? 1262 GLN A O   1 
ATOM   8008 C CB  . GLN A 1 1140 ? 142.710 150.703 227.162 1.00 171.73 ? 1262 GLN A CB  1 
ATOM   8009 N N   . LEU A 1 1141 ? 142.629 151.557 223.527 1.00 176.53 ? 1263 LEU A N   1 
ATOM   8010 C CA  . LEU A 1 1141 ? 143.232 151.203 222.250 1.00 172.87 ? 1263 LEU A CA  1 
ATOM   8011 C C   . LEU A 1 1141 ? 144.005 152.401 221.714 1.00 168.01 ? 1263 LEU A C   1 
ATOM   8012 O O   . LEU A 1 1141 ? 143.436 153.485 221.546 1.00 169.25 ? 1263 LEU A O   1 
ATOM   8013 C CB  . LEU A 1 1141 ? 142.158 150.765 221.256 1.00 171.16 ? 1263 LEU A CB  1 
ATOM   8014 C CG  . LEU A 1 1141 ? 142.610 150.193 219.914 1.00 169.68 ? 1263 LEU A CG  1 
ATOM   8015 C CD1 . LEU A 1 1141 ? 143.392 148.907 220.112 1.00 164.11 ? 1263 LEU A CD1 1 
ATOM   8016 C CD2 . LEU A 1 1141 ? 141.400 149.961 219.027 1.00 171.81 ? 1263 LEU A CD2 1 
ATOM   8017 N N   . GLN A 1 1142 ? 145.292 152.202 221.448 1.00 162.41 ? 1264 GLN A N   1 
ATOM   8018 C CA  . GLN A 1 1142 ? 146.132 153.238 220.863 1.00 161.37 ? 1264 GLN A CA  1 
ATOM   8019 C C   . GLN A 1 1142 ? 146.004 153.152 219.346 1.00 161.31 ? 1264 GLN A C   1 
ATOM   8020 O O   . GLN A 1 1142 ? 146.294 152.108 218.753 1.00 162.38 ? 1264 GLN A O   1 
ATOM   8021 C CB  . GLN A 1 1142 ? 147.582 153.069 221.317 1.00 159.38 ? 1264 GLN A CB  1 
ATOM   8022 C CG  . GLN A 1 1142 ? 148.455 154.294 221.096 1.00 159.51 ? 1264 GLN A CG  1 
ATOM   8023 C CD  . GLN A 1 1142 ? 149.889 154.101 221.566 1.00 161.40 ? 1264 GLN A CD  1 
ATOM   8024 O OE1 . GLN A 1 1142 ? 150.676 155.048 221.586 1.00 162.65 ? 1264 GLN A OE1 1 
ATOM   8025 N NE2 . GLN A 1 1142 ? 150.235 152.875 221.950 1.00 161.78 ? 1264 GLN A NE2 1 
ATOM   8026 N N   . LEU A 1 1143 ? 145.576 154.246 218.725 1.00 156.79 ? 1265 LEU A N   1 
ATOM   8027 C CA  . LEU A 1 1143 ? 145.017 154.223 217.381 1.00 152.32 ? 1265 LEU A CA  1 
ATOM   8028 C C   . LEU A 1 1143 ? 145.751 155.219 216.491 1.00 147.90 ? 1265 LEU A C   1 
ATOM   8029 O O   . LEU A 1 1143 ? 145.744 156.421 216.768 1.00 150.50 ? 1265 LEU A O   1 
ATOM   8030 C CB  . LEU A 1 1143 ? 143.526 154.560 217.444 1.00 154.09 ? 1265 LEU A CB  1 
ATOM   8031 C CG  . LEU A 1 1143 ? 142.691 154.535 216.175 1.00 151.08 ? 1265 LEU A CG  1 
ATOM   8032 C CD1 . LEU A 1 1143 ? 142.708 153.129 215.660 1.00 150.07 ? 1265 LEU A CD1 1 
ATOM   8033 C CD2 . LEU A 1 1143 ? 141.273 154.983 216.465 1.00 152.68 ? 1265 LEU A CD2 1 
ATOM   8034 N N   . LYS A 1 1144 ? 146.353 154.731 215.409 1.00 144.99 ? 1266 LYS A N   1 
ATOM   8035 C CA  . LYS A 1 1144 ? 147.172 155.571 214.543 1.00 144.22 ? 1266 LYS A CA  1 
ATOM   8036 C C   . LYS A 1 1144 ? 146.412 155.867 213.254 1.00 141.21 ? 1266 LYS A C   1 
ATOM   8037 O O   . LYS A 1 1144 ? 145.880 154.954 212.616 1.00 143.01 ? 1266 LYS A O   1 
ATOM   8038 C CB  . LYS A 1 1144 ? 148.519 154.912 214.248 1.00 144.47 ? 1266 LYS A CB  1 
ATOM   8039 C CG  . LYS A 1 1144 ? 149.538 155.877 213.667 1.00 144.68 ? 1266 LYS A CG  1 
ATOM   8040 C CD  . LYS A 1 1144 ? 150.806 155.172 213.224 1.00 147.09 ? 1266 LYS A CD  1 
ATOM   8041 C CE  . LYS A 1 1144 ? 151.718 156.118 212.458 1.00 147.09 ? 1266 LYS A CE  1 
ATOM   8042 N NZ  . LYS A 1 1144 ? 152.954 155.436 211.983 1.00 145.70 ? 1266 LYS A NZ  1 
ATOM   8043 N N   . ILE A 1 1145 ? 146.372 157.146 212.880 1.00 135.62 ? 1267 ILE A N   1 
ATOM   8044 C CA  . ILE A 1 1145 ? 145.479 157.664 211.850 1.00 132.38 ? 1267 ILE A CA  1 
ATOM   8045 C C   . ILE A 1 1145 ? 146.325 158.252 210.727 1.00 133.04 ? 1267 ILE A C   1 
ATOM   8046 O O   . ILE A 1 1145 ? 147.234 159.051 210.980 1.00 136.87 ? 1267 ILE A O   1 
ATOM   8047 C CB  . ILE A 1 1145 ? 144.530 158.729 212.447 1.00 137.16 ? 1267 ILE A CB  1 
ATOM   8048 C CG1 . ILE A 1 1145 ? 143.690 158.152 213.590 1.00 141.08 ? 1267 ILE A CG1 1 
ATOM   8049 C CG2 . ILE A 1 1145 ? 143.605 159.322 211.397 1.00 131.89 ? 1267 ILE A CG2 1 
ATOM   8050 C CD1 . ILE A 1 1145 ? 142.794 157.009 213.186 1.00 139.64 ? 1267 ILE A CD1 1 
ATOM   8051 N N   . SER A 1 1146 ? 146.044 157.846 209.487 1.00 129.37 ? 1268 SER A N   1 
ATOM   8052 C CA  . SER A 1 1146 ? 146.682 158.429 208.312 1.00 123.91 ? 1268 SER A CA  1 
ATOM   8053 C C   . SER A 1 1146 ? 145.626 158.998 207.376 1.00 120.08 ? 1268 SER A C   1 
ATOM   8054 O O   . SER A 1 1146 ? 144.699 158.287 206.979 1.00 122.42 ? 1268 SER A O   1 
ATOM   8055 C CB  . SER A 1 1146 ? 147.538 157.399 207.576 1.00 124.01 ? 1268 SER A CB  1 
ATOM   8056 O OG  . SER A 1 1146 ? 148.462 156.785 208.455 1.00 130.91 ? 1268 SER A OG  1 
ATOM   8057 N N   . ILE A 1 1147 ? 145.774 160.272 207.018 1.00 118.24 ? 1269 ILE A N   1 
ATOM   8058 C CA  . ILE A 1 1147 ? 144.870 160.956 206.097 1.00 117.24 ? 1269 ILE A CA  1 
ATOM   8059 C C   . ILE A 1 1147 ? 145.641 161.259 204.825 1.00 116.06 ? 1269 ILE A C   1 
ATOM   8060 O O   . ILE A 1 1147 ? 146.628 162.002 204.862 1.00 119.15 ? 1269 ILE A O   1 
ATOM   8061 C CB  . ILE A 1 1147 ? 144.313 162.265 206.680 1.00 121.34 ? 1269 ILE A CB  1 
ATOM   8062 C CG1 . ILE A 1 1147 ? 143.726 162.093 208.081 1.00 121.73 ? 1269 ILE A CG1 1 
ATOM   8063 C CG2 . ILE A 1 1147 ? 143.250 162.825 205.750 1.00 117.72 ? 1269 ILE A CG2 1 
ATOM   8064 C CD1 . ILE A 1 1147 ? 142.643 161.081 208.170 1.00 121.22 ? 1269 ILE A CD1 1 
ATOM   8065 N N   . THR A 1 1148 ? 145.183 160.725 203.703 1.00 108.86 ? 1270 THR A N   1 
ATOM   8066 C CA  . THR A 1 1148 ? 145.735 161.118 202.409 1.00 105.35 ? 1270 THR A CA  1 
ATOM   8067 C C   . THR A 1 1148 ? 144.623 161.763 201.597 1.00 104.41 ? 1270 THR A C   1 
ATOM   8068 O O   . THR A 1 1148 ? 143.758 161.046 201.057 1.00 107.26 ? 1270 THR A O   1 
ATOM   8069 C CB  . THR A 1 1148 ? 146.336 159.926 201.665 1.00 100.99 ? 1270 THR A CB  1 
ATOM   8070 O OG1 . THR A 1 1148 ? 147.361 159.338 202.472 1.00 109.39 ? 1270 THR A OG1 1 
ATOM   8071 C CG2 . THR A 1 1148 ? 146.981 160.383 200.359 1.00 97.31  ? 1270 THR A CG2 1 
ATOM   8072 N N   . PRO A 1 1149 ? 144.557 163.093 201.524 1.00 100.88 ? 1271 PRO A N   1 
ATOM   8073 C CA  . PRO A 1 1149 ? 143.592 163.728 200.622 1.00 96.91  ? 1271 PRO A CA  1 
ATOM   8074 C C   . PRO A 1 1149 ? 144.049 163.620 199.178 1.00 97.97  ? 1271 PRO A C   1 
ATOM   8075 O O   . PRO A 1 1149 ? 145.247 163.578 198.887 1.00 102.88 ? 1271 PRO A O   1 
ATOM   8076 C CB  . PRO A 1 1149 ? 143.570 165.183 201.098 1.00 103.33 ? 1271 PRO A CB  1 
ATOM   8077 C CG  . PRO A 1 1149 ? 144.907 165.388 201.708 1.00 101.42 ? 1271 PRO A CG  1 
ATOM   8078 C CD  . PRO A 1 1149 ? 145.258 164.085 202.357 1.00 101.80 ? 1271 PRO A CD  1 
ATOM   8079 N N   . ARG A 1 1150 ? 143.084 163.571 198.265 1.00 94.42  ? 1272 ARG A N   1 
ATOM   8080 C CA  . ARG A 1 1150 ? 143.395 163.451 196.852 1.00 91.34  ? 1272 ARG A CA  1 
ATOM   8081 C C   . ARG A 1 1150 ? 142.321 164.146 196.035 1.00 95.57  ? 1272 ARG A C   1 
ATOM   8082 O O   . ARG A 1 1150 ? 141.210 164.385 196.511 1.00 105.25 ? 1272 ARG A O   1 
ATOM   8083 C CB  . ARG A 1 1150 ? 143.503 161.986 196.411 1.00 92.70  ? 1272 ARG A CB  1 
ATOM   8084 C CG  . ARG A 1 1150 ? 142.233 161.194 196.617 1.00 98.49  ? 1272 ARG A CG  1 
ATOM   8085 C CD  . ARG A 1 1150 ? 142.382 159.750 196.217 1.00 103.72 ? 1272 ARG A CD  1 
ATOM   8086 N NE  . ARG A 1 1150 ? 141.155 159.012 196.483 1.00 112.83 ? 1272 ARG A NE  1 
ATOM   8087 C CZ  . ARG A 1 1150 ? 140.216 158.768 195.580 1.00 115.89 ? 1272 ARG A CZ  1 
ATOM   8088 N NH1 . ARG A 1 1150 ? 140.333 159.188 194.332 1.00 113.60 ? 1272 ARG A NH1 1 
ATOM   8089 N NH2 . ARG A 1 1150 ? 139.134 158.084 195.939 1.00 115.58 ? 1272 ARG A NH2 1 
ATOM   8090 N N   . THR A 1 1151 ? 142.672 164.477 194.800 1.00 89.27  ? 1273 THR A N   1 
ATOM   8091 C CA  . THR A 1 1151 ? 141.753 165.024 193.820 1.00 84.72  ? 1273 THR A CA  1 
ATOM   8092 C C   . THR A 1 1151 ? 141.920 164.058 192.635 1.00 86.89  ? 1273 THR A C   1 
ATOM   8093 O O   . THR A 1 1151 ? 142.640 163.062 192.759 1.00 94.45  ? 1273 THR A O   1 
ATOM   8094 C CB  . THR A 1 1151 ? 142.109 166.527 193.608 1.00 84.42  ? 1273 THR A CB  1 
ATOM   8095 O OG1 . THR A 1 1151 ? 141.999 167.166 194.880 1.00 91.06  ? 1273 THR A OG1 1 
ATOM   8096 C CG2 . THR A 1 1151 ? 141.078 167.359 192.812 1.00 91.99  ? 1273 THR A CG2 1 
ATOM   8097 N N   . ALA A 1 1152 ? 141.247 164.284 191.498 1.00 81.71  ? 1274 ALA A N   1 
ATOM   8098 C CA  . ALA A 1 1152 ? 141.378 163.391 190.349 1.00 78.82  ? 1274 ALA A CA  1 
ATOM   8099 C C   . ALA A 1 1152 ? 142.713 163.571 189.629 1.00 80.52  ? 1274 ALA A C   1 
ATOM   8100 O O   . ALA A 1 1152 ? 143.145 162.685 188.883 1.00 84.51  ? 1274 ALA A O   1 
ATOM   8101 C CB  . ALA A 1 1152 ? 140.219 163.618 189.383 1.00 72.77  ? 1274 ALA A CB  1 
ATOM   8102 N N   . TRP A 1 1153 ? 143.384 164.707 189.836 1.00 77.15  ? 1275 TRP A N   1 
ATOM   8103 C CA  . TRP A 1 1153 ? 144.669 164.940 189.188 1.00 75.86  ? 1275 TRP A CA  1 
ATOM   8104 C C   . TRP A 1 1153 ? 145.837 164.557 190.091 1.00 84.44  ? 1275 TRP A C   1 
ATOM   8105 O O   . TRP A 1 1153 ? 146.833 163.996 189.621 1.00 92.74  ? 1275 TRP A O   1 
ATOM   8106 C CB  . TRP A 1 1153 ? 144.782 166.402 188.758 1.00 79.60  ? 1275 TRP A CB  1 
ATOM   8107 C CG  . TRP A 1 1153 ? 143.750 166.814 187.767 1.00 76.42  ? 1275 TRP A CG  1 
ATOM   8108 C CD1 . TRP A 1 1153 ? 143.836 166.720 186.414 1.00 78.16  ? 1275 TRP A CD1 1 
ATOM   8109 C CD2 . TRP A 1 1153 ? 142.470 167.378 188.048 1.00 78.18  ? 1275 TRP A CD2 1 
ATOM   8110 N NE1 . TRP A 1 1153 ? 142.691 167.194 185.831 1.00 81.34  ? 1275 TRP A NE1 1 
ATOM   8111 C CE2 . TRP A 1 1153 ? 141.833 167.604 186.815 1.00 81.55  ? 1275 TRP A CE2 1 
ATOM   8112 C CE3 . TRP A 1 1153 ? 141.797 167.712 189.226 1.00 80.97  ? 1275 TRP A CE3 1 
ATOM   8113 C CZ2 . TRP A 1 1153 ? 140.555 168.152 186.726 1.00 83.47  ? 1275 TRP A CZ2 1 
ATOM   8114 C CZ3 . TRP A 1 1153 ? 140.528 168.258 189.139 1.00 84.40  ? 1275 TRP A CZ3 1 
ATOM   8115 C CH2 . TRP A 1 1153 ? 139.921 168.472 187.897 1.00 86.46  ? 1275 TRP A CH2 1 
ATOM   8116 N N   . ARG A 1 1154 ? 145.744 164.853 191.385 1.00 82.20  ? 1276 ARG A N   1 
ATOM   8117 C CA  . ARG A 1 1154 ? 146.919 164.794 192.242 1.00 78.03  ? 1276 ARG A CA  1 
ATOM   8118 C C   . ARG A 1 1154 ? 146.520 164.507 193.684 1.00 87.30  ? 1276 ARG A C   1 
ATOM   8119 O O   . ARG A 1 1154 ? 145.589 165.113 194.218 1.00 98.80  ? 1276 ARG A O   1 
ATOM   8120 C CB  . ARG A 1 1154 ? 147.706 166.110 192.142 1.00 76.93  ? 1276 ARG A CB  1 
ATOM   8121 C CG  . ARG A 1 1154 ? 149.001 166.153 192.917 1.00 80.45  ? 1276 ARG A CG  1 
ATOM   8122 C CD  . ARG A 1 1154 ? 149.749 167.444 192.688 1.00 81.70  ? 1276 ARG A CD  1 
ATOM   8123 N NE  . ARG A 1 1154 ? 150.976 167.487 193.470 1.00 88.98  ? 1276 ARG A NE  1 
ATOM   8124 C CZ  . ARG A 1 1154 ? 151.843 168.489 193.451 1.00 97.63  ? 1276 ARG A CZ  1 
ATOM   8125 N NH1 . ARG A 1 1154 ? 151.688 169.519 192.638 1.00 95.93  ? 1276 ARG A NH1 1 
ATOM   8126 N NH2 . ARG A 1 1154 ? 152.903 168.445 194.252 1.00 101.19 ? 1276 ARG A NH2 1 
ATOM   8127 N N   . SER A 1 1155 ? 147.236 163.573 194.309 1.00 83.43  ? 1277 SER A N   1 
ATOM   8128 C CA  . SER A 1 1155 ? 147.105 163.297 195.730 1.00 86.87  ? 1277 SER A CA  1 
ATOM   8129 C C   . SER A 1 1155 ? 147.921 164.294 196.549 1.00 91.18  ? 1277 SER A C   1 
ATOM   8130 O O   . SER A 1 1155 ? 148.878 164.898 196.064 1.00 96.22  ? 1277 SER A O   1 
ATOM   8131 C CB  . SER A 1 1155 ? 147.561 161.874 196.050 1.00 87.84  ? 1277 SER A CB  1 
ATOM   8132 O OG  . SER A 1 1155 ? 146.746 160.917 195.401 1.00 95.65  ? 1277 SER A OG  1 
ATOM   8133 N N   . GLY A 1 1156 ? 147.532 164.455 197.814 1.00 92.38  ? 1278 GLY A N   1 
ATOM   8134 C CA  . GLY A 1 1156 ? 148.187 165.370 198.719 1.00 93.90  ? 1278 GLY A CA  1 
ATOM   8135 C C   . GLY A 1 1156 ? 149.122 164.657 199.682 1.00 98.75  ? 1278 GLY A C   1 
ATOM   8136 O O   . GLY A 1 1156 ? 149.344 163.448 199.597 1.00 105.37 ? 1278 GLY A O   1 
ATOM   8137 N N   . ASP A 1 1157 ? 149.671 165.444 200.605 1.00 103.52 ? 1279 ASP A N   1 
ATOM   8138 C CA  . ASP A 1 1157 ? 150.578 164.910 201.611 1.00 109.01 ? 1279 ASP A CA  1 
ATOM   8139 C C   . ASP A 1 1157 ? 149.806 164.165 202.695 1.00 108.73 ? 1279 ASP A C   1 
ATOM   8140 O O   . ASP A 1 1157 ? 148.592 164.313 202.850 1.00 107.02 ? 1279 ASP A O   1 
ATOM   8141 C CB  . ASP A 1 1157 ? 151.410 166.028 202.236 1.00 110.07 ? 1279 ASP A CB  1 
ATOM   8142 C CG  . ASP A 1 1157 ? 152.449 166.584 201.283 1.00 113.45 ? 1279 ASP A CG  1 
ATOM   8143 O OD1 . ASP A 1 1157 ? 152.645 165.996 200.199 1.00 110.83 ? 1279 ASP A OD1 1 
ATOM   8144 O OD2 . ASP A 1 1157 ? 153.075 167.609 201.621 1.00 118.08 ? 1279 ASP A OD2 1 
ATOM   8145 N N   . THR A 1 1158 ? 150.536 163.361 203.461 1.00 112.17 ? 1280 THR A N   1 
ATOM   8146 C CA  . THR A 1 1158 ? 149.947 162.448 204.430 1.00 116.50 ? 1280 THR A CA  1 
ATOM   8147 C C   . THR A 1 1158 ? 150.023 163.040 205.832 1.00 120.87 ? 1280 THR A C   1 
ATOM   8148 O O   . THR A 1 1158 ? 151.095 163.468 206.274 1.00 126.02 ? 1280 THR A O   1 
ATOM   8149 C CB  . THR A 1 1158 ? 150.654 161.093 204.386 1.00 116.42 ? 1280 THR A CB  1 
ATOM   8150 O OG1 . THR A 1 1158 ? 150.832 160.696 203.021 1.00 114.81 ? 1280 THR A OG1 1 
ATOM   8151 C CG2 . THR A 1 1158 ? 149.833 160.035 205.102 1.00 113.26 ? 1280 THR A CG2 1 
ATOM   8152 N N   . THR A 1 1159 ? 148.886 163.060 206.526 1.00 117.98 ? 1281 THR A N   1 
ATOM   8153 C CA  . THR A 1 1159 ? 148.810 163.543 207.898 1.00 122.69 ? 1281 THR A CA  1 
ATOM   8154 C C   . THR A 1 1159 ? 148.788 162.354 208.851 1.00 124.81 ? 1281 THR A C   1 
ATOM   8155 O O   . THR A 1 1159 ? 147.823 161.584 208.866 1.00 123.30 ? 1281 THR A O   1 
ATOM   8156 C CB  . THR A 1 1159 ? 147.564 164.404 208.100 1.00 121.85 ? 1281 THR A CB  1 
ATOM   8157 O OG1 . THR A 1 1159 ? 147.587 165.503 207.181 1.00 122.52 ? 1281 THR A OG1 1 
ATOM   8158 C CG2 . THR A 1 1159 ? 147.509 164.936 209.520 1.00 127.18 ? 1281 THR A CG2 1 
ATOM   8159 N N   . ARG A 1 1160 ? 149.840 162.212 209.654 1.00 125.78 ? 1282 ARG A N   1 
ATOM   8160 C CA  . ARG A 1 1160 ? 149.998 161.077 210.557 1.00 130.08 ? 1282 ARG A CA  1 
ATOM   8161 C C   . ARG A 1 1160 ? 149.940 161.583 211.994 1.00 133.52 ? 1282 ARG A C   1 
ATOM   8162 O O   . ARG A 1 1160 ? 150.877 162.236 212.464 1.00 131.55 ? 1282 ARG A O   1 
ATOM   8163 C CB  . ARG A 1 1160 ? 151.315 160.354 210.283 1.00 126.76 ? 1282 ARG A CB  1 
ATOM   8164 C CG  . ARG A 1 1160 ? 151.418 159.767 208.888 1.00 123.85 ? 1282 ARG A CG  1 
ATOM   8165 C CD  . ARG A 1 1160 ? 152.818 159.254 208.615 1.00 123.37 ? 1282 ARG A CD  1 
ATOM   8166 N NE  . ARG A 1 1160 ? 152.986 158.827 207.232 1.00 128.08 ? 1282 ARG A NE  1 
ATOM   8167 C CZ  . ARG A 1 1160 ? 153.426 159.611 206.258 1.00 122.48 ? 1282 ARG A CZ  1 
ATOM   8168 N NH1 . ARG A 1 1160 ? 153.755 160.873 206.481 1.00 115.91 ? 1282 ARG A NH1 1 
ATOM   8169 N NH2 . ARG A 1 1160 ? 153.543 159.115 205.029 1.00 117.52 ? 1282 ARG A NH2 1 
ATOM   8170 N N   . VAL A 1 1161 ? 148.843 161.277 212.690 1.00 133.65 ? 1283 VAL A N   1 
ATOM   8171 C CA  . VAL A 1 1161 ? 148.641 161.687 214.078 1.00 136.31 ? 1283 VAL A CA  1 
ATOM   8172 C C   . VAL A 1 1161 ? 148.536 160.438 214.945 1.00 137.61 ? 1283 VAL A C   1 
ATOM   8173 O O   . VAL A 1 1161 ? 148.420 159.322 214.425 1.00 137.10 ? 1283 VAL A O   1 
ATOM   8174 C CB  . VAL A 1 1161 ? 147.390 162.579 214.257 1.00 138.58 ? 1283 VAL A CB  1 
ATOM   8175 C CG1 . VAL A 1 1161 ? 147.359 163.721 213.249 1.00 135.79 ? 1283 VAL A CG1 1 
ATOM   8176 C CG2 . VAL A 1 1161 ? 146.108 161.768 214.153 1.00 135.14 ? 1283 VAL A CG2 1 
ATOM   8177 N N   . GLN A 1 1162 ? 148.608 160.627 216.263 1.00 143.71 ? 1284 GLN A N   1 
ATOM   8178 C CA  . GLN A 1 1162 ? 148.435 159.554 217.238 1.00 148.30 ? 1284 GLN A CA  1 
ATOM   8179 C C   . GLN A 1 1162 ? 147.319 159.959 218.197 1.00 149.19 ? 1284 GLN A C   1 
ATOM   8180 O O   . GLN A 1 1162 ? 147.418 160.985 218.878 1.00 149.09 ? 1284 GLN A O   1 
ATOM   8181 C CB  . GLN A 1 1162 ? 149.739 159.278 217.983 1.00 147.41 ? 1284 GLN A CB  1 
ATOM   8182 C CG  . GLN A 1 1162 ? 149.664 158.126 218.968 1.00 148.51 ? 1284 GLN A CG  1 
ATOM   8183 C CD  . GLN A 1 1162 ? 149.349 156.807 218.297 1.00 152.34 ? 1284 GLN A CD  1 
ATOM   8184 O OE1 . GLN A 1 1162 ? 148.229 156.308 218.385 1.00 153.93 ? 1284 GLN A OE1 1 
ATOM   8185 N NE2 . GLN A 1 1162 ? 150.334 156.239 217.612 1.00 152.26 ? 1284 GLN A NE2 1 
ATOM   8186 N N   . LEU A 1 1163 ? 146.258 159.157 218.242 1.00 149.89 ? 1285 LEU A N   1 
ATOM   8187 C CA  . LEU A 1 1163 ? 145.036 159.491 218.961 1.00 154.00 ? 1285 LEU A CA  1 
ATOM   8188 C C   . LEU A 1 1163 ? 144.626 158.311 219.832 1.00 160.36 ? 1285 LEU A C   1 
ATOM   8189 O O   . LEU A 1 1163 ? 144.493 157.189 219.337 1.00 162.20 ? 1285 LEU A O   1 
ATOM   8190 C CB  . LEU A 1 1163 ? 143.935 159.865 217.956 1.00 152.78 ? 1285 LEU A CB  1 
ATOM   8191 C CG  . LEU A 1 1163 ? 142.545 160.439 218.266 1.00 157.28 ? 1285 LEU A CG  1 
ATOM   8192 C CD1 . LEU A 1 1163 ? 142.113 161.242 217.057 1.00 155.06 ? 1285 LEU A CD1 1 
ATOM   8193 C CD2 . LEU A 1 1163 ? 141.473 159.389 218.559 1.00 158.87 ? 1285 LEU A CD2 1 
ATOM   8194 N N   . THR A 1 1164 ? 144.400 158.566 221.119 1.00 163.14 ? 1286 THR A N   1 
ATOM   8195 C CA  . THR A 1 1164 ? 143.941 157.541 222.048 1.00 164.34 ? 1286 THR A CA  1 
ATOM   8196 C C   . THR A 1 1164 ? 142.433 157.649 222.229 1.00 167.20 ? 1286 THR A C   1 
ATOM   8197 O O   . THR A 1 1164 ? 141.900 158.753 222.386 1.00 168.49 ? 1286 THR A O   1 
ATOM   8198 C CB  . THR A 1 1164 ? 144.642 157.668 223.401 1.00 161.66 ? 1286 THR A CB  1 
ATOM   8199 O OG1 . THR A 1 1164 ? 144.395 158.968 223.949 1.00 166.45 ? 1286 THR A OG1 1 
ATOM   8200 C CG2 . THR A 1 1164 ? 146.141 157.460 223.247 1.00 152.44 ? 1286 THR A CG2 1 
ATOM   8201 N N   . THR A 1 1165 ? 141.750 156.509 222.210 1.00 168.11 ? 1287 THR A N   1 
ATOM   8202 C CA  . THR A 1 1165 ? 140.300 156.485 222.373 1.00 170.77 ? 1287 THR A CA  1 
ATOM   8203 C C   . THR A 1 1165 ? 139.904 156.663 223.836 1.00 165.35 ? 1287 THR A C   1 
ATOM   8204 O O   . THR A 1 1165 ? 138.733 156.523 224.193 1.00 163.72 ? 1287 THR A O   1 
ATOM   8205 C CB  . THR A 1 1165 ? 139.691 155.175 221.844 1.00 171.92 ? 1287 THR A CB  1 
ATOM   8206 O OG1 . THR A 1 1165 ? 139.941 154.116 222.777 1.00 172.77 ? 1287 THR A OG1 1 
ATOM   8207 C CG2 . THR A 1 1165 ? 140.297 154.812 220.501 1.00 166.74 ? 1287 THR A CG2 1 
HETATM 8208 C C1  . NAG B 2 .    ? 161.875 171.898 183.286 1.00 103.52 ? 1    NAG B C1  1 
HETATM 8209 C C2  . NAG B 2 .    ? 162.498 173.139 183.961 1.00 114.17 ? 1    NAG B C2  1 
HETATM 8210 C C3  . NAG B 2 .    ? 163.482 172.796 185.114 1.00 123.74 ? 1    NAG B C3  1 
HETATM 8211 C C4  . NAG B 2 .    ? 163.220 171.541 185.975 1.00 123.08 ? 1    NAG B C4  1 
HETATM 8212 C C5  . NAG B 2 .    ? 162.655 170.400 185.114 1.00 110.70 ? 1    NAG B C5  1 
HETATM 8213 C C6  . NAG B 2 .    ? 162.102 169.236 185.910 1.00 108.72 ? 1    NAG B C6  1 
HETATM 8214 C C7  . NAG B 2 .    ? 162.678 175.208 182.624 1.00 116.14 ? 1    NAG B C7  1 
HETATM 8215 C C8  . NAG B 2 .    ? 163.550 175.923 181.623 1.00 115.29 ? 1    NAG B C8  1 
HETATM 8216 N N2  . NAG B 2 .    ? 163.144 174.004 183.006 1.00 113.36 ? 1    NAG B N2  1 
HETATM 8217 O O3  . NAG B 2 .    ? 163.577 173.929 185.946 1.00 127.60 ? 1    NAG B O3  1 
HETATM 8218 O O4  . NAG B 2 .    ? 164.464 171.207 186.575 1.00 129.25 ? 1    NAG B O4  1 
HETATM 8219 O O5  . NAG B 2 .    ? 161.607 170.985 184.354 1.00 107.55 ? 1    NAG B O5  1 
HETATM 8220 O O6  . NAG B 2 .    ? 161.442 168.294 185.095 1.00 105.90 ? 1    NAG B O6  1 
HETATM 8221 O O7  . NAG B 2 .    ? 161.637 175.697 183.040 1.00 113.38 ? 1    NAG B O7  1 
HETATM 8222 C C1  . NAG B 2 .    ? 164.447 171.292 188.014 1.00 139.60 ? 2    NAG B C1  1 
HETATM 8223 C C2  . NAG B 2 .    ? 165.419 170.195 188.490 1.00 136.63 ? 2    NAG B C2  1 
HETATM 8224 C C3  . NAG B 2 .    ? 166.156 170.585 189.785 1.00 142.98 ? 2    NAG B C3  1 
HETATM 8225 C C4  . NAG B 2 .    ? 166.694 172.014 189.827 1.00 147.74 ? 2    NAG B C4  1 
HETATM 8226 C C5  . NAG B 2 .    ? 165.481 172.941 189.655 1.00 150.93 ? 2    NAG B C5  1 
HETATM 8227 C C6  . NAG B 2 .    ? 165.846 174.412 189.627 1.00 147.98 ? 2    NAG B C6  1 
HETATM 8228 C C7  . NAG B 2 .    ? 165.106 167.746 188.353 1.00 122.78 ? 2    NAG B C7  1 
HETATM 8229 C C8  . NAG B 2 .    ? 164.170 166.613 188.681 1.00 109.59 ? 2    NAG B C8  1 
HETATM 8230 N N2  . NAG B 2 .    ? 164.690 168.977 188.707 1.00 127.09 ? 2    NAG B N2  1 
HETATM 8231 O O3  . NAG B 2 .    ? 167.188 169.649 189.935 1.00 143.55 ? 2    NAG B O3  1 
HETATM 8232 O O4  . NAG B 2 .    ? 167.373 172.232 191.050 1.00 152.41 ? 2    NAG B O4  1 
HETATM 8233 O O5  . NAG B 2 .    ? 164.799 172.612 188.436 1.00 152.18 ? 2    NAG B O5  1 
HETATM 8234 O O6  . NAG B 2 .    ? 167.188 174.580 189.198 1.00 145.60 ? 2    NAG B O6  1 
HETATM 8235 O O7  . NAG B 2 .    ? 166.170 167.526 187.798 1.00 123.43 ? 2    NAG B O7  1 
HETATM 8236 C C1  . NAG C 3 .    ? 128.115 154.537 126.848 1.00 98.99  ? 2601 NAG A C1  1 
HETATM 8237 C C2  . NAG C 3 .    ? 128.396 155.981 127.365 1.00 103.25 ? 2601 NAG A C2  1 
HETATM 8238 C C3  . NAG C 3 .    ? 128.380 155.942 128.902 1.00 103.71 ? 2601 NAG A C3  1 
HETATM 8239 C C4  . NAG C 3 .    ? 127.054 155.445 129.485 1.00 103.73 ? 2601 NAG A C4  1 
HETATM 8240 C C5  . NAG C 3 .    ? 126.705 154.078 128.870 1.00 103.29 ? 2601 NAG A C5  1 
HETATM 8241 C C6  . NAG C 3 .    ? 125.297 153.636 129.178 1.00 100.32 ? 2601 NAG A C6  1 
HETATM 8242 C C7  . NAG C 3 .    ? 129.808 157.751 126.256 1.00 109.41 ? 2601 NAG A C7  1 
HETATM 8243 C C8  . NAG C 3 .    ? 128.598 158.594 125.904 1.00 104.40 ? 2601 NAG A C8  1 
HETATM 8244 N N2  . NAG C 3 .    ? 129.628 156.583 126.919 1.00 106.25 ? 2601 NAG A N2  1 
HETATM 8245 O O3  . NAG C 3 .    ? 128.700 157.227 129.370 1.00 102.80 ? 2601 NAG A O3  1 
HETATM 8246 O O4  . NAG C 3 .    ? 127.210 155.373 130.888 1.00 102.53 ? 2601 NAG A O4  1 
HETATM 8247 O O5  . NAG C 3 .    ? 126.882 154.123 127.443 1.00 102.79 ? 2601 NAG A O5  1 
HETATM 8248 O O6  . NAG C 3 .    ? 125.105 152.310 128.751 1.00 98.84  ? 2601 NAG A O6  1 
HETATM 8249 O O7  . NAG C 3 .    ? 130.926 158.129 125.945 1.00 111.01 ? 2601 NAG A O7  1 
HETATM 8250 C C1  . NAG D 3 .    ? 135.537 178.385 195.754 1.00 153.57 ? 2602 NAG A C1  1 
HETATM 8251 C C2  . NAG D 3 .    ? 135.573 179.519 194.704 1.00 153.90 ? 2602 NAG A C2  1 
HETATM 8252 C C3  . NAG D 3 .    ? 135.807 180.868 195.419 1.00 159.37 ? 2602 NAG A C3  1 
HETATM 8253 C C4  . NAG D 3 .    ? 134.887 181.153 196.622 1.00 162.57 ? 2602 NAG A C4  1 
HETATM 8254 C C5  . NAG D 3 .    ? 134.888 179.931 197.565 1.00 161.35 ? 2602 NAG A C5  1 
HETATM 8255 C C6  . NAG D 3 .    ? 133.886 180.026 198.693 1.00 157.37 ? 2602 NAG A C6  1 
HETATM 8256 C C7  . NAG D 3 .    ? 136.327 178.829 192.464 1.00 145.49 ? 2602 NAG A C7  1 
HETATM 8257 C C8  . NAG D 3 .    ? 137.539 178.673 191.581 1.00 134.64 ? 2602 NAG A C8  1 
HETATM 8258 N N2  . NAG D 3 .    ? 136.580 179.291 193.703 1.00 149.08 ? 2602 NAG A N2  1 
HETATM 8259 O O3  . NAG D 3 .    ? 135.710 181.880 194.450 1.00 158.27 ? 2602 NAG A O3  1 
HETATM 8260 O O4  . NAG D 3 .    ? 135.362 182.315 197.261 1.00 158.05 ? 2602 NAG A O4  1 
HETATM 8261 O O5  . NAG D 3 .    ? 134.631 178.748 196.798 1.00 158.53 ? 2602 NAG A O5  1 
HETATM 8262 O O6  . NAG D 3 .    ? 132.614 180.329 198.171 1.00 152.69 ? 2602 NAG A O6  1 
HETATM 8263 O O7  . NAG D 3 .    ? 135.207 178.547 192.066 1.00 142.25 ? 2602 NAG A O7  1 
# 
