data_9BFK
# 
_entry.id   9BFK 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BFK         pdb_00009bfk 10.2210/pdb9bfk/pdb 
WWPDB D_1000283312 ?            ?                   
EMDB  EMD-44499    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-06 
2 'Structure model' 1 1 2025-01-15 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
12 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BFK 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-18 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        'Cryo-EM structure of human CHT1 in the ML352 bound state' 
_pdbx_database_related.db_id          EMD-44499 
_pdbx_database_related.content_type   'associated EM volume' 
# 
loop_
_pdbx_contact_author.id 
_pdbx_contact_author.email 
_pdbx_contact_author.name_first 
_pdbx_contact_author.name_last 
_pdbx_contact_author.name_mi 
_pdbx_contact_author.role 
_pdbx_contact_author.identifier_ORCID 
2 jxue1990@outlook.com             Jing    Xue   ? 'principal investigator/group leader' 0000-0002-7331-1382 
3 Youxing.Jiang@UTSouthwestern.edu Youxing Jiang ? 'principal investigator/group leader' 0000-0002-1874-0504 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Xue, J.'   1 0000-0002-7331-1382 
'Jiang, Y.' 2 0000-0002-1874-0504 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Cell Discov' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2056-5968 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            10 
_citation.language                  ? 
_citation.page_first                116 
_citation.page_last                 116 
_citation.title                     'Structural mechanisms of human sodium-coupled high-affinity choline transporter CHT1.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41421-024-00731-7 
_citation.pdbx_database_id_PubMed   39587078 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Xue, J.'   1 0000-0002-7331-1382 
primary 'Chen, H.'  2 ?                   
primary 'Wang, Y.'  3 0000-0001-9156-0377 
primary 'Jiang, Y.' 4 0000-0002-1874-0504 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'High affinity choline transporter 1'                                                            66526.625 1 ? ? 
? ? 
2 non-polymer syn '4-methoxy-3-[(1-methylpiperidin-4-yl)oxy]-N-{[3-(propan-2-yl)-1,2-oxazol-5-yl]methyl}benzamide' 387.473   1 ? ? 
? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'hCHT1,Hemicholinium-3-sensitive choline transporter,CHT,Solute carrier family 5 member 7' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGY
GLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVD
MHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMIL
PIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTK
TVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNK
EAFLDVDSSPEGSGTEDNLQAAAGGSWSHPQFEKGGGSGGGSGGSAWSHPQFEK
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGY
GLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVD
MHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMIL
PIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTK
TVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNK
EAFLDVDSSPEGSGTEDNLQAAAGGSWSHPQFEKGGGSGGGSGGSAWSHPQFEK
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
_pdbx_entity_nonpoly.entity_id   2 
_pdbx_entity_nonpoly.name        '4-methoxy-3-[(1-methylpiperidin-4-yl)oxy]-N-{[3-(propan-2-yl)-1,2-oxazol-5-yl]methyl}benzamide' 
_pdbx_entity_nonpoly.comp_id     A1AOW 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   ALA n 
1 3   PHE n 
1 4   HIS n 
1 5   VAL n 
1 6   GLU n 
1 7   GLY n 
1 8   LEU n 
1 9   ILE n 
1 10  ALA n 
1 11  ILE n 
1 12  ILE n 
1 13  VAL n 
1 14  PHE n 
1 15  TYR n 
1 16  LEU n 
1 17  LEU n 
1 18  ILE n 
1 19  LEU n 
1 20  LEU n 
1 21  VAL n 
1 22  GLY n 
1 23  ILE n 
1 24  TRP n 
1 25  ALA n 
1 26  ALA n 
1 27  TRP n 
1 28  ARG n 
1 29  THR n 
1 30  LYS n 
1 31  ASN n 
1 32  SER n 
1 33  GLY n 
1 34  SER n 
1 35  ALA n 
1 36  GLU n 
1 37  GLU n 
1 38  ARG n 
1 39  SER n 
1 40  GLU n 
1 41  ALA n 
1 42  ILE n 
1 43  ILE n 
1 44  VAL n 
1 45  GLY n 
1 46  GLY n 
1 47  ARG n 
1 48  ASP n 
1 49  ILE n 
1 50  GLY n 
1 51  LEU n 
1 52  LEU n 
1 53  VAL n 
1 54  GLY n 
1 55  GLY n 
1 56  PHE n 
1 57  THR n 
1 58  MET n 
1 59  THR n 
1 60  ALA n 
1 61  THR n 
1 62  TRP n 
1 63  VAL n 
1 64  GLY n 
1 65  GLY n 
1 66  GLY n 
1 67  TYR n 
1 68  ILE n 
1 69  ASN n 
1 70  GLY n 
1 71  THR n 
1 72  ALA n 
1 73  GLU n 
1 74  ALA n 
1 75  VAL n 
1 76  TYR n 
1 77  VAL n 
1 78  PRO n 
1 79  GLY n 
1 80  TYR n 
1 81  GLY n 
1 82  LEU n 
1 83  ALA n 
1 84  TRP n 
1 85  ALA n 
1 86  GLN n 
1 87  ALA n 
1 88  PRO n 
1 89  ILE n 
1 90  GLY n 
1 91  TYR n 
1 92  SER n 
1 93  LEU n 
1 94  SER n 
1 95  LEU n 
1 96  ILE n 
1 97  LEU n 
1 98  GLY n 
1 99  GLY n 
1 100 LEU n 
1 101 PHE n 
1 102 PHE n 
1 103 ALA n 
1 104 LYS n 
1 105 PRO n 
1 106 MET n 
1 107 ARG n 
1 108 SER n 
1 109 LYS n 
1 110 GLY n 
1 111 TYR n 
1 112 VAL n 
1 113 THR n 
1 114 MET n 
1 115 LEU n 
1 116 ASP n 
1 117 PRO n 
1 118 PHE n 
1 119 GLN n 
1 120 GLN n 
1 121 ILE n 
1 122 TYR n 
1 123 GLY n 
1 124 LYS n 
1 125 ARG n 
1 126 MET n 
1 127 GLY n 
1 128 GLY n 
1 129 LEU n 
1 130 LEU n 
1 131 PHE n 
1 132 ILE n 
1 133 PRO n 
1 134 ALA n 
1 135 LEU n 
1 136 MET n 
1 137 GLY n 
1 138 GLU n 
1 139 MET n 
1 140 PHE n 
1 141 TRP n 
1 142 ALA n 
1 143 ALA n 
1 144 ALA n 
1 145 ILE n 
1 146 PHE n 
1 147 SER n 
1 148 ALA n 
1 149 LEU n 
1 150 GLY n 
1 151 ALA n 
1 152 THR n 
1 153 ILE n 
1 154 SER n 
1 155 VAL n 
1 156 ILE n 
1 157 ILE n 
1 158 ASP n 
1 159 VAL n 
1 160 ASP n 
1 161 MET n 
1 162 HIS n 
1 163 ILE n 
1 164 SER n 
1 165 VAL n 
1 166 ILE n 
1 167 ILE n 
1 168 SER n 
1 169 ALA n 
1 170 LEU n 
1 171 ILE n 
1 172 ALA n 
1 173 THR n 
1 174 LEU n 
1 175 TYR n 
1 176 THR n 
1 177 LEU n 
1 178 VAL n 
1 179 GLY n 
1 180 GLY n 
1 181 LEU n 
1 182 TYR n 
1 183 SER n 
1 184 VAL n 
1 185 ALA n 
1 186 TYR n 
1 187 THR n 
1 188 ASP n 
1 189 VAL n 
1 190 VAL n 
1 191 GLN n 
1 192 LEU n 
1 193 PHE n 
1 194 CYS n 
1 195 ILE n 
1 196 PHE n 
1 197 VAL n 
1 198 GLY n 
1 199 LEU n 
1 200 TRP n 
1 201 ILE n 
1 202 SER n 
1 203 VAL n 
1 204 PRO n 
1 205 PHE n 
1 206 ALA n 
1 207 LEU n 
1 208 SER n 
1 209 HIS n 
1 210 PRO n 
1 211 ALA n 
1 212 VAL n 
1 213 ALA n 
1 214 ASP n 
1 215 ILE n 
1 216 GLY n 
1 217 PHE n 
1 218 THR n 
1 219 ALA n 
1 220 VAL n 
1 221 HIS n 
1 222 ALA n 
1 223 LYS n 
1 224 TYR n 
1 225 GLN n 
1 226 LYS n 
1 227 PRO n 
1 228 TRP n 
1 229 LEU n 
1 230 GLY n 
1 231 THR n 
1 232 VAL n 
1 233 ASP n 
1 234 SER n 
1 235 SER n 
1 236 GLU n 
1 237 VAL n 
1 238 TYR n 
1 239 SER n 
1 240 TRP n 
1 241 LEU n 
1 242 ASP n 
1 243 SER n 
1 244 PHE n 
1 245 LEU n 
1 246 LEU n 
1 247 LEU n 
1 248 MET n 
1 249 LEU n 
1 250 GLY n 
1 251 GLY n 
1 252 ILE n 
1 253 PRO n 
1 254 TRP n 
1 255 GLN n 
1 256 ALA n 
1 257 TYR n 
1 258 PHE n 
1 259 GLN n 
1 260 ARG n 
1 261 VAL n 
1 262 LEU n 
1 263 SER n 
1 264 SER n 
1 265 SER n 
1 266 SER n 
1 267 ALA n 
1 268 THR n 
1 269 TYR n 
1 270 ALA n 
1 271 GLN n 
1 272 VAL n 
1 273 LEU n 
1 274 SER n 
1 275 PHE n 
1 276 LEU n 
1 277 ALA n 
1 278 ALA n 
1 279 PHE n 
1 280 GLY n 
1 281 CYS n 
1 282 LEU n 
1 283 VAL n 
1 284 MET n 
1 285 ALA n 
1 286 ILE n 
1 287 PRO n 
1 288 ALA n 
1 289 ILE n 
1 290 LEU n 
1 291 ILE n 
1 292 GLY n 
1 293 ALA n 
1 294 ILE n 
1 295 GLY n 
1 296 ALA n 
1 297 SER n 
1 298 THR n 
1 299 ASP n 
1 300 TRP n 
1 301 ASN n 
1 302 GLN n 
1 303 THR n 
1 304 ALA n 
1 305 TYR n 
1 306 GLY n 
1 307 LEU n 
1 308 PRO n 
1 309 ASP n 
1 310 PRO n 
1 311 LYS n 
1 312 THR n 
1 313 THR n 
1 314 GLU n 
1 315 GLU n 
1 316 ALA n 
1 317 ASP n 
1 318 MET n 
1 319 ILE n 
1 320 LEU n 
1 321 PRO n 
1 322 ILE n 
1 323 VAL n 
1 324 LEU n 
1 325 GLN n 
1 326 TYR n 
1 327 LEU n 
1 328 CYS n 
1 329 PRO n 
1 330 VAL n 
1 331 TYR n 
1 332 ILE n 
1 333 SER n 
1 334 PHE n 
1 335 PHE n 
1 336 GLY n 
1 337 LEU n 
1 338 GLY n 
1 339 ALA n 
1 340 VAL n 
1 341 SER n 
1 342 ALA n 
1 343 ALA n 
1 344 VAL n 
1 345 MET n 
1 346 SER n 
1 347 SER n 
1 348 ALA n 
1 349 ASP n 
1 350 SER n 
1 351 SER n 
1 352 ILE n 
1 353 LEU n 
1 354 SER n 
1 355 ALA n 
1 356 SER n 
1 357 SER n 
1 358 MET n 
1 359 PHE n 
1 360 ALA n 
1 361 ARG n 
1 362 ASN n 
1 363 ILE n 
1 364 TYR n 
1 365 GLN n 
1 366 LEU n 
1 367 SER n 
1 368 PHE n 
1 369 ARG n 
1 370 GLN n 
1 371 ASN n 
1 372 ALA n 
1 373 SER n 
1 374 ASP n 
1 375 LYS n 
1 376 GLU n 
1 377 ILE n 
1 378 VAL n 
1 379 TRP n 
1 380 VAL n 
1 381 MET n 
1 382 ARG n 
1 383 ILE n 
1 384 THR n 
1 385 VAL n 
1 386 PHE n 
1 387 VAL n 
1 388 PHE n 
1 389 GLY n 
1 390 ALA n 
1 391 SER n 
1 392 ALA n 
1 393 THR n 
1 394 ALA n 
1 395 MET n 
1 396 ALA n 
1 397 LEU n 
1 398 LEU n 
1 399 THR n 
1 400 LYS n 
1 401 THR n 
1 402 VAL n 
1 403 TYR n 
1 404 GLY n 
1 405 LEU n 
1 406 TRP n 
1 407 TYR n 
1 408 LEU n 
1 409 SER n 
1 410 SER n 
1 411 ASP n 
1 412 LEU n 
1 413 VAL n 
1 414 TYR n 
1 415 ILE n 
1 416 VAL n 
1 417 ILE n 
1 418 PHE n 
1 419 PRO n 
1 420 GLN n 
1 421 LEU n 
1 422 LEU n 
1 423 CYS n 
1 424 VAL n 
1 425 LEU n 
1 426 PHE n 
1 427 VAL n 
1 428 LYS n 
1 429 GLY n 
1 430 THR n 
1 431 ASN n 
1 432 THR n 
1 433 TYR n 
1 434 GLY n 
1 435 ALA n 
1 436 VAL n 
1 437 ALA n 
1 438 GLY n 
1 439 TYR n 
1 440 VAL n 
1 441 SER n 
1 442 GLY n 
1 443 LEU n 
1 444 PHE n 
1 445 LEU n 
1 446 ARG n 
1 447 ILE n 
1 448 THR n 
1 449 GLY n 
1 450 GLY n 
1 451 GLU n 
1 452 PRO n 
1 453 TYR n 
1 454 LEU n 
1 455 TYR n 
1 456 LEU n 
1 457 GLN n 
1 458 PRO n 
1 459 LEU n 
1 460 ILE n 
1 461 PHE n 
1 462 TYR n 
1 463 PRO n 
1 464 GLY n 
1 465 TYR n 
1 466 TYR n 
1 467 PRO n 
1 468 ASP n 
1 469 ASP n 
1 470 ASN n 
1 471 GLY n 
1 472 ILE n 
1 473 TYR n 
1 474 ASN n 
1 475 GLN n 
1 476 LYS n 
1 477 PHE n 
1 478 PRO n 
1 479 PHE n 
1 480 LYS n 
1 481 THR n 
1 482 LEU n 
1 483 ALA n 
1 484 MET n 
1 485 VAL n 
1 486 THR n 
1 487 SER n 
1 488 PHE n 
1 489 LEU n 
1 490 THR n 
1 491 ASN n 
1 492 ILE n 
1 493 CYS n 
1 494 ILE n 
1 495 SER n 
1 496 TYR n 
1 497 LEU n 
1 498 ALA n 
1 499 LYS n 
1 500 TYR n 
1 501 LEU n 
1 502 PHE n 
1 503 GLU n 
1 504 SER n 
1 505 GLY n 
1 506 THR n 
1 507 LEU n 
1 508 PRO n 
1 509 PRO n 
1 510 LYS n 
1 511 LEU n 
1 512 ASP n 
1 513 VAL n 
1 514 PHE n 
1 515 ASP n 
1 516 ALA n 
1 517 VAL n 
1 518 VAL n 
1 519 ALA n 
1 520 ARG n 
1 521 HIS n 
1 522 SER n 
1 523 GLU n 
1 524 GLU n 
1 525 ASN n 
1 526 MET n 
1 527 ASP n 
1 528 LYS n 
1 529 THR n 
1 530 ILE n 
1 531 LEU n 
1 532 VAL n 
1 533 LYS n 
1 534 ASN n 
1 535 GLU n 
1 536 ASN n 
1 537 ILE n 
1 538 LYS n 
1 539 LEU n 
1 540 ASP n 
1 541 GLU n 
1 542 LEU n 
1 543 ALA n 
1 544 LEU n 
1 545 VAL n 
1 546 LYS n 
1 547 PRO n 
1 548 ARG n 
1 549 GLN n 
1 550 SER n 
1 551 MET n 
1 552 THR n 
1 553 LEU n 
1 554 SER n 
1 555 SER n 
1 556 THR n 
1 557 PHE n 
1 558 THR n 
1 559 ASN n 
1 560 LYS n 
1 561 GLU n 
1 562 ALA n 
1 563 PHE n 
1 564 LEU n 
1 565 ASP n 
1 566 VAL n 
1 567 ASP n 
1 568 SER n 
1 569 SER n 
1 570 PRO n 
1 571 GLU n 
1 572 GLY n 
1 573 SER n 
1 574 GLY n 
1 575 THR n 
1 576 GLU n 
1 577 ASP n 
1 578 ASN n 
1 579 LEU n 
1 580 GLN n 
1 581 ALA n 
1 582 ALA n 
1 583 ALA n 
1 584 GLY n 
1 585 GLY n 
1 586 SER n 
1 587 TRP n 
1 588 SER n 
1 589 HIS n 
1 590 PRO n 
1 591 GLN n 
1 592 PHE n 
1 593 GLU n 
1 594 LYS n 
1 595 GLY n 
1 596 GLY n 
1 597 GLY n 
1 598 SER n 
1 599 GLY n 
1 600 GLY n 
1 601 GLY n 
1 602 SER n 
1 603 GLY n 
1 604 GLY n 
1 605 SER n 
1 606 ALA n 
1 607 TRP n 
1 608 SER n 
1 609 HIS n 
1 610 PRO n 
1 611 GLN n 
1 612 PHE n 
1 613 GLU n 
1 614 LYS n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   614 
_entity_src_gen.gene_src_common_name               human 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'SLC5A7, CHT1' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     9606 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Homo sapiens' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     9606 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AOW non-polymer         . '4-methoxy-3-[(1-methylpiperidin-4-yl)oxy]-N-{[3-(propan-2-yl)-1,2-oxazol-5-yl]methyl}benzamide' ? 
'C21 H29 N3 O4'  387.473 
ALA   'L-peptide linking' y ALANINE                                                                                          ? 
'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                                                                         ? 
'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                                                                       ? 
'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                                                                                  ? 
'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                                                                         ? 
'C3 H7 N O2 S'   121.158 
GLN   'L-peptide linking' y GLUTAMINE                                                                                        ? 
'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                                                                                  ? 
'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                                                                          ? 
'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                                                                        ? 
'C6 H10 N3 O2 1' 156.162 
ILE   'L-peptide linking' y ISOLEUCINE                                                                                       ? 
'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                                                                          ? 
'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                                                                           ? 
'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                                                                       ? 
'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                                                                    ? 
'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                                                                          ? 
'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                                                                           ? 
'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                                                                        ? 
'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                                                                       ? 
'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                                                                         ? 
'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                                                                           ? 
'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   ALA 2   2   2   ALA ALA A . n 
A 1 3   PHE 3   3   3   PHE PHE A . n 
A 1 4   HIS 4   4   4   HIS HIS A . n 
A 1 5   VAL 5   5   5   VAL VAL A . n 
A 1 6   GLU 6   6   6   GLU GLU A . n 
A 1 7   GLY 7   7   7   GLY GLY A . n 
A 1 8   LEU 8   8   8   LEU LEU A . n 
A 1 9   ILE 9   9   9   ILE ILE A . n 
A 1 10  ALA 10  10  10  ALA ALA A . n 
A 1 11  ILE 11  11  11  ILE ILE A . n 
A 1 12  ILE 12  12  12  ILE ILE A . n 
A 1 13  VAL 13  13  13  VAL VAL A . n 
A 1 14  PHE 14  14  14  PHE PHE A . n 
A 1 15  TYR 15  15  15  TYR TYR A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  LEU 17  17  17  LEU LEU A . n 
A 1 18  ILE 18  18  18  ILE ILE A . n 
A 1 19  LEU 19  19  19  LEU LEU A . n 
A 1 20  LEU 20  20  20  LEU LEU A . n 
A 1 21  VAL 21  21  21  VAL VAL A . n 
A 1 22  GLY 22  22  22  GLY GLY A . n 
A 1 23  ILE 23  23  23  ILE ILE A . n 
A 1 24  TRP 24  24  24  TRP TRP A . n 
A 1 25  ALA 25  25  25  ALA ALA A . n 
A 1 26  ALA 26  26  26  ALA ALA A . n 
A 1 27  TRP 27  27  27  TRP TRP A . n 
A 1 28  ARG 28  28  28  ARG ARG A . n 
A 1 29  THR 29  29  29  THR THR A . n 
A 1 30  LYS 30  30  ?   ?   ?   A . n 
A 1 31  ASN 31  31  ?   ?   ?   A . n 
A 1 32  SER 32  32  ?   ?   ?   A . n 
A 1 33  GLY 33  33  ?   ?   ?   A . n 
A 1 34  SER 34  34  ?   ?   ?   A . n 
A 1 35  ALA 35  35  ?   ?   ?   A . n 
A 1 36  GLU 36  36  ?   ?   ?   A . n 
A 1 37  GLU 37  37  ?   ?   ?   A . n 
A 1 38  ARG 38  38  ?   ?   ?   A . n 
A 1 39  SER 39  39  ?   ?   ?   A . n 
A 1 40  GLU 40  40  ?   ?   ?   A . n 
A 1 41  ALA 41  41  ?   ?   ?   A . n 
A 1 42  ILE 42  42  ?   ?   ?   A . n 
A 1 43  ILE 43  43  ?   ?   ?   A . n 
A 1 44  VAL 44  44  ?   ?   ?   A . n 
A 1 45  GLY 45  45  ?   ?   ?   A . n 
A 1 46  GLY 46  46  ?   ?   ?   A . n 
A 1 47  ARG 47  47  47  ARG ARG A . n 
A 1 48  ASP 48  48  48  ASP ASP A . n 
A 1 49  ILE 49  49  49  ILE ILE A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  LEU 51  51  51  LEU LEU A . n 
A 1 52  LEU 52  52  52  LEU LEU A . n 
A 1 53  VAL 53  53  53  VAL VAL A . n 
A 1 54  GLY 54  54  54  GLY GLY A . n 
A 1 55  GLY 55  55  55  GLY GLY A . n 
A 1 56  PHE 56  56  56  PHE PHE A . n 
A 1 57  THR 57  57  57  THR THR A . n 
A 1 58  MET 58  58  58  MET MET A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  ALA 60  60  60  ALA ALA A . n 
A 1 61  THR 61  61  61  THR THR A . n 
A 1 62  TRP 62  62  62  TRP TRP A . n 
A 1 63  VAL 63  63  63  VAL VAL A . n 
A 1 64  GLY 64  64  64  GLY GLY A . n 
A 1 65  GLY 65  65  65  GLY GLY A . n 
A 1 66  GLY 66  66  66  GLY GLY A . n 
A 1 67  TYR 67  67  67  TYR TYR A . n 
A 1 68  ILE 68  68  68  ILE ILE A . n 
A 1 69  ASN 69  69  69  ASN ASN A . n 
A 1 70  GLY 70  70  70  GLY GLY A . n 
A 1 71  THR 71  71  71  THR THR A . n 
A 1 72  ALA 72  72  72  ALA ALA A . n 
A 1 73  GLU 73  73  73  GLU GLU A . n 
A 1 74  ALA 74  74  74  ALA ALA A . n 
A 1 75  VAL 75  75  75  VAL VAL A . n 
A 1 76  TYR 76  76  76  TYR TYR A . n 
A 1 77  VAL 77  77  77  VAL VAL A . n 
A 1 78  PRO 78  78  78  PRO PRO A . n 
A 1 79  GLY 79  79  79  GLY GLY A . n 
A 1 80  TYR 80  80  80  TYR TYR A . n 
A 1 81  GLY 81  81  81  GLY GLY A . n 
A 1 82  LEU 82  82  82  LEU LEU A . n 
A 1 83  ALA 83  83  83  ALA ALA A . n 
A 1 84  TRP 84  84  84  TRP TRP A . n 
A 1 85  ALA 85  85  85  ALA ALA A . n 
A 1 86  GLN 86  86  86  GLN GLN A . n 
A 1 87  ALA 87  87  87  ALA ALA A . n 
A 1 88  PRO 88  88  88  PRO PRO A . n 
A 1 89  ILE 89  89  89  ILE ILE A . n 
A 1 90  GLY 90  90  90  GLY GLY A . n 
A 1 91  TYR 91  91  91  TYR TYR A . n 
A 1 92  SER 92  92  92  SER SER A . n 
A 1 93  LEU 93  93  93  LEU LEU A . n 
A 1 94  SER 94  94  94  SER SER A . n 
A 1 95  LEU 95  95  95  LEU LEU A . n 
A 1 96  ILE 96  96  96  ILE ILE A . n 
A 1 97  LEU 97  97  97  LEU LEU A . n 
A 1 98  GLY 98  98  98  GLY GLY A . n 
A 1 99  GLY 99  99  99  GLY GLY A . n 
A 1 100 LEU 100 100 100 LEU LEU A . n 
A 1 101 PHE 101 101 101 PHE PHE A . n 
A 1 102 PHE 102 102 102 PHE PHE A . n 
A 1 103 ALA 103 103 103 ALA ALA A . n 
A 1 104 LYS 104 104 104 LYS LYS A . n 
A 1 105 PRO 105 105 105 PRO PRO A . n 
A 1 106 MET 106 106 106 MET MET A . n 
A 1 107 ARG 107 107 107 ARG ARG A . n 
A 1 108 SER 108 108 108 SER SER A . n 
A 1 109 LYS 109 109 109 LYS LYS A . n 
A 1 110 GLY 110 110 110 GLY GLY A . n 
A 1 111 TYR 111 111 111 TYR TYR A . n 
A 1 112 VAL 112 112 112 VAL VAL A . n 
A 1 113 THR 113 113 113 THR THR A . n 
A 1 114 MET 114 114 114 MET MET A . n 
A 1 115 LEU 115 115 115 LEU LEU A . n 
A 1 116 ASP 116 116 116 ASP ASP A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 PHE 118 118 118 PHE PHE A . n 
A 1 119 GLN 119 119 119 GLN GLN A . n 
A 1 120 GLN 120 120 120 GLN GLN A . n 
A 1 121 ILE 121 121 121 ILE ILE A . n 
A 1 122 TYR 122 122 122 TYR TYR A . n 
A 1 123 GLY 123 123 123 GLY GLY A . n 
A 1 124 LYS 124 124 124 LYS LYS A . n 
A 1 125 ARG 125 125 125 ARG ARG A . n 
A 1 126 MET 126 126 126 MET MET A . n 
A 1 127 GLY 127 127 127 GLY GLY A . n 
A 1 128 GLY 128 128 128 GLY GLY A . n 
A 1 129 LEU 129 129 129 LEU LEU A . n 
A 1 130 LEU 130 130 130 LEU LEU A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 ILE 132 132 132 ILE ILE A . n 
A 1 133 PRO 133 133 133 PRO PRO A . n 
A 1 134 ALA 134 134 134 ALA ALA A . n 
A 1 135 LEU 135 135 135 LEU LEU A . n 
A 1 136 MET 136 136 136 MET MET A . n 
A 1 137 GLY 137 137 137 GLY GLY A . n 
A 1 138 GLU 138 138 138 GLU GLU A . n 
A 1 139 MET 139 139 139 MET MET A . n 
A 1 140 PHE 140 140 140 PHE PHE A . n 
A 1 141 TRP 141 141 141 TRP TRP A . n 
A 1 142 ALA 142 142 142 ALA ALA A . n 
A 1 143 ALA 143 143 143 ALA ALA A . n 
A 1 144 ALA 144 144 144 ALA ALA A . n 
A 1 145 ILE 145 145 145 ILE ILE A . n 
A 1 146 PHE 146 146 146 PHE PHE A . n 
A 1 147 SER 147 147 147 SER SER A . n 
A 1 148 ALA 148 148 148 ALA ALA A . n 
A 1 149 LEU 149 149 149 LEU LEU A . n 
A 1 150 GLY 150 150 150 GLY GLY A . n 
A 1 151 ALA 151 151 151 ALA ALA A . n 
A 1 152 THR 152 152 152 THR THR A . n 
A 1 153 ILE 153 153 153 ILE ILE A . n 
A 1 154 SER 154 154 154 SER SER A . n 
A 1 155 VAL 155 155 155 VAL VAL A . n 
A 1 156 ILE 156 156 156 ILE ILE A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 ASP 158 158 158 ASP ASP A . n 
A 1 159 VAL 159 159 159 VAL VAL A . n 
A 1 160 ASP 160 160 160 ASP ASP A . n 
A 1 161 MET 161 161 161 MET MET A . n 
A 1 162 HIS 162 162 162 HIS HIS A . n 
A 1 163 ILE 163 163 163 ILE ILE A . n 
A 1 164 SER 164 164 164 SER SER A . n 
A 1 165 VAL 165 165 165 VAL VAL A . n 
A 1 166 ILE 166 166 166 ILE ILE A . n 
A 1 167 ILE 167 167 167 ILE ILE A . n 
A 1 168 SER 168 168 168 SER SER A . n 
A 1 169 ALA 169 169 169 ALA ALA A . n 
A 1 170 LEU 170 170 170 LEU LEU A . n 
A 1 171 ILE 171 171 171 ILE ILE A . n 
A 1 172 ALA 172 172 172 ALA ALA A . n 
A 1 173 THR 173 173 173 THR THR A . n 
A 1 174 LEU 174 174 174 LEU LEU A . n 
A 1 175 TYR 175 175 175 TYR TYR A . n 
A 1 176 THR 176 176 176 THR THR A . n 
A 1 177 LEU 177 177 177 LEU LEU A . n 
A 1 178 VAL 178 178 178 VAL VAL A . n 
A 1 179 GLY 179 179 179 GLY GLY A . n 
A 1 180 GLY 180 180 ?   ?   ?   A . n 
A 1 181 LEU 181 181 ?   ?   ?   A . n 
A 1 182 TYR 182 182 ?   ?   ?   A . n 
A 1 183 SER 183 183 183 SER SER A . n 
A 1 184 VAL 184 184 184 VAL VAL A . n 
A 1 185 ALA 185 185 185 ALA ALA A . n 
A 1 186 TYR 186 186 186 TYR TYR A . n 
A 1 187 THR 187 187 187 THR THR A . n 
A 1 188 ASP 188 188 188 ASP ASP A . n 
A 1 189 VAL 189 189 189 VAL VAL A . n 
A 1 190 VAL 190 190 190 VAL VAL A . n 
A 1 191 GLN 191 191 191 GLN GLN A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 PHE 193 193 193 PHE PHE A . n 
A 1 194 CYS 194 194 194 CYS CYS A . n 
A 1 195 ILE 195 195 195 ILE ILE A . n 
A 1 196 PHE 196 196 196 PHE PHE A . n 
A 1 197 VAL 197 197 197 VAL VAL A . n 
A 1 198 GLY 198 198 198 GLY GLY A . n 
A 1 199 LEU 199 199 199 LEU LEU A . n 
A 1 200 TRP 200 200 200 TRP TRP A . n 
A 1 201 ILE 201 201 201 ILE ILE A . n 
A 1 202 SER 202 202 202 SER SER A . n 
A 1 203 VAL 203 203 203 VAL VAL A . n 
A 1 204 PRO 204 204 204 PRO PRO A . n 
A 1 205 PHE 205 205 205 PHE PHE A . n 
A 1 206 ALA 206 206 206 ALA ALA A . n 
A 1 207 LEU 207 207 207 LEU LEU A . n 
A 1 208 SER 208 208 208 SER SER A . n 
A 1 209 HIS 209 209 209 HIS HIS A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ALA 211 211 211 ALA ALA A . n 
A 1 212 VAL 212 212 212 VAL VAL A . n 
A 1 213 ALA 213 213 213 ALA ALA A . n 
A 1 214 ASP 214 214 214 ASP ASP A . n 
A 1 215 ILE 215 215 215 ILE ILE A . n 
A 1 216 GLY 216 216 216 GLY GLY A . n 
A 1 217 PHE 217 217 217 PHE PHE A . n 
A 1 218 THR 218 218 218 THR THR A . n 
A 1 219 ALA 219 219 219 ALA ALA A . n 
A 1 220 VAL 220 220 220 VAL VAL A . n 
A 1 221 HIS 221 221 221 HIS HIS A . n 
A 1 222 ALA 222 222 222 ALA ALA A . n 
A 1 223 LYS 223 223 223 LYS LYS A . n 
A 1 224 TYR 224 224 224 TYR TYR A . n 
A 1 225 GLN 225 225 225 GLN GLN A . n 
A 1 226 LYS 226 226 226 LYS LYS A . n 
A 1 227 PRO 227 227 227 PRO PRO A . n 
A 1 228 TRP 228 228 228 TRP TRP A . n 
A 1 229 LEU 229 229 229 LEU LEU A . n 
A 1 230 GLY 230 230 230 GLY GLY A . n 
A 1 231 THR 231 231 231 THR THR A . n 
A 1 232 VAL 232 232 232 VAL VAL A . n 
A 1 233 ASP 233 233 233 ASP ASP A . n 
A 1 234 SER 234 234 234 SER SER A . n 
A 1 235 SER 235 235 235 SER SER A . n 
A 1 236 GLU 236 236 236 GLU GLU A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 TYR 238 238 238 TYR TYR A . n 
A 1 239 SER 239 239 239 SER SER A . n 
A 1 240 TRP 240 240 240 TRP TRP A . n 
A 1 241 LEU 241 241 241 LEU LEU A . n 
A 1 242 ASP 242 242 242 ASP ASP A . n 
A 1 243 SER 243 243 243 SER SER A . n 
A 1 244 PHE 244 244 244 PHE PHE A . n 
A 1 245 LEU 245 245 245 LEU LEU A . n 
A 1 246 LEU 246 246 246 LEU LEU A . n 
A 1 247 LEU 247 247 247 LEU LEU A . n 
A 1 248 MET 248 248 248 MET MET A . n 
A 1 249 LEU 249 249 249 LEU LEU A . n 
A 1 250 GLY 250 250 250 GLY GLY A . n 
A 1 251 GLY 251 251 251 GLY GLY A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 PRO 253 253 253 PRO PRO A . n 
A 1 254 TRP 254 254 254 TRP TRP A . n 
A 1 255 GLN 255 255 255 GLN GLN A . n 
A 1 256 ALA 256 256 256 ALA ALA A . n 
A 1 257 TYR 257 257 257 TYR TYR A . n 
A 1 258 PHE 258 258 258 PHE PHE A . n 
A 1 259 GLN 259 259 259 GLN GLN A . n 
A 1 260 ARG 260 260 260 ARG ARG A . n 
A 1 261 VAL 261 261 261 VAL VAL A . n 
A 1 262 LEU 262 262 262 LEU LEU A . n 
A 1 263 SER 263 263 263 SER SER A . n 
A 1 264 SER 264 264 264 SER SER A . n 
A 1 265 SER 265 265 265 SER SER A . n 
A 1 266 SER 266 266 266 SER SER A . n 
A 1 267 ALA 267 267 267 ALA ALA A . n 
A 1 268 THR 268 268 268 THR THR A . n 
A 1 269 TYR 269 269 269 TYR TYR A . n 
A 1 270 ALA 270 270 270 ALA ALA A . n 
A 1 271 GLN 271 271 271 GLN GLN A . n 
A 1 272 VAL 272 272 272 VAL VAL A . n 
A 1 273 LEU 273 273 273 LEU LEU A . n 
A 1 274 SER 274 274 274 SER SER A . n 
A 1 275 PHE 275 275 275 PHE PHE A . n 
A 1 276 LEU 276 276 276 LEU LEU A . n 
A 1 277 ALA 277 277 277 ALA ALA A . n 
A 1 278 ALA 278 278 278 ALA ALA A . n 
A 1 279 PHE 279 279 279 PHE PHE A . n 
A 1 280 GLY 280 280 280 GLY GLY A . n 
A 1 281 CYS 281 281 281 CYS CYS A . n 
A 1 282 LEU 282 282 282 LEU LEU A . n 
A 1 283 VAL 283 283 283 VAL VAL A . n 
A 1 284 MET 284 284 284 MET MET A . n 
A 1 285 ALA 285 285 285 ALA ALA A . n 
A 1 286 ILE 286 286 286 ILE ILE A . n 
A 1 287 PRO 287 287 287 PRO PRO A . n 
A 1 288 ALA 288 288 288 ALA ALA A . n 
A 1 289 ILE 289 289 289 ILE ILE A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 ILE 291 291 291 ILE ILE A . n 
A 1 292 GLY 292 292 292 GLY GLY A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 ILE 294 294 294 ILE ILE A . n 
A 1 295 GLY 295 295 295 GLY GLY A . n 
A 1 296 ALA 296 296 296 ALA ALA A . n 
A 1 297 SER 297 297 297 SER SER A . n 
A 1 298 THR 298 298 298 THR THR A . n 
A 1 299 ASP 299 299 299 ASP ASP A . n 
A 1 300 TRP 300 300 300 TRP TRP A . n 
A 1 301 ASN 301 301 301 ASN ASN A . n 
A 1 302 GLN 302 302 302 GLN GLN A . n 
A 1 303 THR 303 303 303 THR THR A . n 
A 1 304 ALA 304 304 304 ALA ALA A . n 
A 1 305 TYR 305 305 305 TYR TYR A . n 
A 1 306 GLY 306 306 306 GLY GLY A . n 
A 1 307 LEU 307 307 307 LEU LEU A . n 
A 1 308 PRO 308 308 308 PRO PRO A . n 
A 1 309 ASP 309 309 309 ASP ASP A . n 
A 1 310 PRO 310 310 310 PRO PRO A . n 
A 1 311 LYS 311 311 311 LYS LYS A . n 
A 1 312 THR 312 312 312 THR THR A . n 
A 1 313 THR 313 313 313 THR THR A . n 
A 1 314 GLU 314 314 314 GLU GLU A . n 
A 1 315 GLU 315 315 315 GLU GLU A . n 
A 1 316 ALA 316 316 316 ALA ALA A . n 
A 1 317 ASP 317 317 317 ASP ASP A . n 
A 1 318 MET 318 318 318 MET MET A . n 
A 1 319 ILE 319 319 319 ILE ILE A . n 
A 1 320 LEU 320 320 320 LEU LEU A . n 
A 1 321 PRO 321 321 321 PRO PRO A . n 
A 1 322 ILE 322 322 322 ILE ILE A . n 
A 1 323 VAL 323 323 323 VAL VAL A . n 
A 1 324 LEU 324 324 324 LEU LEU A . n 
A 1 325 GLN 325 325 325 GLN GLN A . n 
A 1 326 TYR 326 326 326 TYR TYR A . n 
A 1 327 LEU 327 327 327 LEU LEU A . n 
A 1 328 CYS 328 328 328 CYS CYS A . n 
A 1 329 PRO 329 329 329 PRO PRO A . n 
A 1 330 VAL 330 330 330 VAL VAL A . n 
A 1 331 TYR 331 331 331 TYR TYR A . n 
A 1 332 ILE 332 332 332 ILE ILE A . n 
A 1 333 SER 333 333 333 SER SER A . n 
A 1 334 PHE 334 334 334 PHE PHE A . n 
A 1 335 PHE 335 335 335 PHE PHE A . n 
A 1 336 GLY 336 336 336 GLY GLY A . n 
A 1 337 LEU 337 337 337 LEU LEU A . n 
A 1 338 GLY 338 338 338 GLY GLY A . n 
A 1 339 ALA 339 339 339 ALA ALA A . n 
A 1 340 VAL 340 340 340 VAL VAL A . n 
A 1 341 SER 341 341 341 SER SER A . n 
A 1 342 ALA 342 342 342 ALA ALA A . n 
A 1 343 ALA 343 343 343 ALA ALA A . n 
A 1 344 VAL 344 344 344 VAL VAL A . n 
A 1 345 MET 345 345 345 MET MET A . n 
A 1 346 SER 346 346 346 SER SER A . n 
A 1 347 SER 347 347 347 SER SER A . n 
A 1 348 ALA 348 348 348 ALA ALA A . n 
A 1 349 ASP 349 349 349 ASP ASP A . n 
A 1 350 SER 350 350 350 SER SER A . n 
A 1 351 SER 351 351 351 SER SER A . n 
A 1 352 ILE 352 352 352 ILE ILE A . n 
A 1 353 LEU 353 353 353 LEU LEU A . n 
A 1 354 SER 354 354 354 SER SER A . n 
A 1 355 ALA 355 355 355 ALA ALA A . n 
A 1 356 SER 356 356 356 SER SER A . n 
A 1 357 SER 357 357 357 SER SER A . n 
A 1 358 MET 358 358 358 MET MET A . n 
A 1 359 PHE 359 359 359 PHE PHE A . n 
A 1 360 ALA 360 360 360 ALA ALA A . n 
A 1 361 ARG 361 361 361 ARG ARG A . n 
A 1 362 ASN 362 362 362 ASN ASN A . n 
A 1 363 ILE 363 363 363 ILE ILE A . n 
A 1 364 TYR 364 364 364 TYR TYR A . n 
A 1 365 GLN 365 365 365 GLN GLN A . n 
A 1 366 LEU 366 366 366 LEU LEU A . n 
A 1 367 SER 367 367 367 SER SER A . n 
A 1 368 PHE 368 368 368 PHE PHE A . n 
A 1 369 ARG 369 369 ?   ?   ?   A . n 
A 1 370 GLN 370 370 ?   ?   ?   A . n 
A 1 371 ASN 371 371 ?   ?   ?   A . n 
A 1 372 ALA 372 372 ?   ?   ?   A . n 
A 1 373 SER 373 373 373 SER SER A . n 
A 1 374 ASP 374 374 374 ASP ASP A . n 
A 1 375 LYS 375 375 375 LYS LYS A . n 
A 1 376 GLU 376 376 376 GLU GLU A . n 
A 1 377 ILE 377 377 377 ILE ILE A . n 
A 1 378 VAL 378 378 378 VAL VAL A . n 
A 1 379 TRP 379 379 379 TRP TRP A . n 
A 1 380 VAL 380 380 380 VAL VAL A . n 
A 1 381 MET 381 381 381 MET MET A . n 
A 1 382 ARG 382 382 382 ARG ARG A . n 
A 1 383 ILE 383 383 383 ILE ILE A . n 
A 1 384 THR 384 384 384 THR THR A . n 
A 1 385 VAL 385 385 385 VAL VAL A . n 
A 1 386 PHE 386 386 386 PHE PHE A . n 
A 1 387 VAL 387 387 387 VAL VAL A . n 
A 1 388 PHE 388 388 388 PHE PHE A . n 
A 1 389 GLY 389 389 389 GLY GLY A . n 
A 1 390 ALA 390 390 390 ALA ALA A . n 
A 1 391 SER 391 391 391 SER SER A . n 
A 1 392 ALA 392 392 392 ALA ALA A . n 
A 1 393 THR 393 393 393 THR THR A . n 
A 1 394 ALA 394 394 394 ALA ALA A . n 
A 1 395 MET 395 395 395 MET MET A . n 
A 1 396 ALA 396 396 396 ALA ALA A . n 
A 1 397 LEU 397 397 397 LEU LEU A . n 
A 1 398 LEU 398 398 398 LEU LEU A . n 
A 1 399 THR 399 399 399 THR THR A . n 
A 1 400 LYS 400 400 400 LYS LYS A . n 
A 1 401 THR 401 401 401 THR THR A . n 
A 1 402 VAL 402 402 402 VAL VAL A . n 
A 1 403 TYR 403 403 403 TYR TYR A . n 
A 1 404 GLY 404 404 404 GLY GLY A . n 
A 1 405 LEU 405 405 405 LEU LEU A . n 
A 1 406 TRP 406 406 406 TRP TRP A . n 
A 1 407 TYR 407 407 407 TYR TYR A . n 
A 1 408 LEU 408 408 408 LEU LEU A . n 
A 1 409 SER 409 409 409 SER SER A . n 
A 1 410 SER 410 410 410 SER SER A . n 
A 1 411 ASP 411 411 411 ASP ASP A . n 
A 1 412 LEU 412 412 412 LEU LEU A . n 
A 1 413 VAL 413 413 413 VAL VAL A . n 
A 1 414 TYR 414 414 414 TYR TYR A . n 
A 1 415 ILE 415 415 415 ILE ILE A . n 
A 1 416 VAL 416 416 416 VAL VAL A . n 
A 1 417 ILE 417 417 417 ILE ILE A . n 
A 1 418 PHE 418 418 418 PHE PHE A . n 
A 1 419 PRO 419 419 419 PRO PRO A . n 
A 1 420 GLN 420 420 420 GLN GLN A . n 
A 1 421 LEU 421 421 421 LEU LEU A . n 
A 1 422 LEU 422 422 422 LEU LEU A . n 
A 1 423 CYS 423 423 423 CYS CYS A . n 
A 1 424 VAL 424 424 424 VAL VAL A . n 
A 1 425 LEU 425 425 425 LEU LEU A . n 
A 1 426 PHE 426 426 426 PHE PHE A . n 
A 1 427 VAL 427 427 427 VAL VAL A . n 
A 1 428 LYS 428 428 428 LYS LYS A . n 
A 1 429 GLY 429 429 429 GLY GLY A . n 
A 1 430 THR 430 430 430 THR THR A . n 
A 1 431 ASN 431 431 431 ASN ASN A . n 
A 1 432 THR 432 432 432 THR THR A . n 
A 1 433 TYR 433 433 433 TYR TYR A . n 
A 1 434 GLY 434 434 434 GLY GLY A . n 
A 1 435 ALA 435 435 435 ALA ALA A . n 
A 1 436 VAL 436 436 436 VAL VAL A . n 
A 1 437 ALA 437 437 437 ALA ALA A . n 
A 1 438 GLY 438 438 438 GLY GLY A . n 
A 1 439 TYR 439 439 439 TYR TYR A . n 
A 1 440 VAL 440 440 440 VAL VAL A . n 
A 1 441 SER 441 441 441 SER SER A . n 
A 1 442 GLY 442 442 442 GLY GLY A . n 
A 1 443 LEU 443 443 443 LEU LEU A . n 
A 1 444 PHE 444 444 444 PHE PHE A . n 
A 1 445 LEU 445 445 445 LEU LEU A . n 
A 1 446 ARG 446 446 446 ARG ARG A . n 
A 1 447 ILE 447 447 447 ILE ILE A . n 
A 1 448 THR 448 448 448 THR THR A . n 
A 1 449 GLY 449 449 449 GLY GLY A . n 
A 1 450 GLY 450 450 450 GLY GLY A . n 
A 1 451 GLU 451 451 451 GLU GLU A . n 
A 1 452 PRO 452 452 452 PRO PRO A . n 
A 1 453 TYR 453 453 453 TYR TYR A . n 
A 1 454 LEU 454 454 454 LEU LEU A . n 
A 1 455 TYR 455 455 455 TYR TYR A . n 
A 1 456 LEU 456 456 456 LEU LEU A . n 
A 1 457 GLN 457 457 457 GLN GLN A . n 
A 1 458 PRO 458 458 458 PRO PRO A . n 
A 1 459 LEU 459 459 459 LEU LEU A . n 
A 1 460 ILE 460 460 460 ILE ILE A . n 
A 1 461 PHE 461 461 461 PHE PHE A . n 
A 1 462 TYR 462 462 462 TYR TYR A . n 
A 1 463 PRO 463 463 463 PRO PRO A . n 
A 1 464 GLY 464 464 464 GLY GLY A . n 
A 1 465 TYR 465 465 465 TYR TYR A . n 
A 1 466 TYR 466 466 466 TYR TYR A . n 
A 1 467 PRO 467 467 467 PRO PRO A . n 
A 1 468 ASP 468 468 468 ASP ASP A . n 
A 1 469 ASP 469 469 469 ASP ASP A . n 
A 1 470 ASN 470 470 470 ASN ASN A . n 
A 1 471 GLY 471 471 471 GLY GLY A . n 
A 1 472 ILE 472 472 472 ILE ILE A . n 
A 1 473 TYR 473 473 473 TYR TYR A . n 
A 1 474 ASN 474 474 474 ASN ASN A . n 
A 1 475 GLN 475 475 475 GLN GLN A . n 
A 1 476 LYS 476 476 476 LYS LYS A . n 
A 1 477 PHE 477 477 477 PHE PHE A . n 
A 1 478 PRO 478 478 478 PRO PRO A . n 
A 1 479 PHE 479 479 479 PHE PHE A . n 
A 1 480 LYS 480 480 480 LYS LYS A . n 
A 1 481 THR 481 481 481 THR THR A . n 
A 1 482 LEU 482 482 482 LEU LEU A . n 
A 1 483 ALA 483 483 483 ALA ALA A . n 
A 1 484 MET 484 484 484 MET MET A . n 
A 1 485 VAL 485 485 485 VAL VAL A . n 
A 1 486 THR 486 486 486 THR THR A . n 
A 1 487 SER 487 487 487 SER SER A . n 
A 1 488 PHE 488 488 488 PHE PHE A . n 
A 1 489 LEU 489 489 489 LEU LEU A . n 
A 1 490 THR 490 490 490 THR THR A . n 
A 1 491 ASN 491 491 491 ASN ASN A . n 
A 1 492 ILE 492 492 492 ILE ILE A . n 
A 1 493 CYS 493 493 493 CYS CYS A . n 
A 1 494 ILE 494 494 494 ILE ILE A . n 
A 1 495 SER 495 495 495 SER SER A . n 
A 1 496 TYR 496 496 496 TYR TYR A . n 
A 1 497 LEU 497 497 497 LEU LEU A . n 
A 1 498 ALA 498 498 498 ALA ALA A . n 
A 1 499 LYS 499 499 499 LYS LYS A . n 
A 1 500 TYR 500 500 500 TYR TYR A . n 
A 1 501 LEU 501 501 501 LEU LEU A . n 
A 1 502 PHE 502 502 502 PHE PHE A . n 
A 1 503 GLU 503 503 503 GLU GLU A . n 
A 1 504 SER 504 504 504 SER SER A . n 
A 1 505 GLY 505 505 505 GLY GLY A . n 
A 1 506 THR 506 506 506 THR THR A . n 
A 1 507 LEU 507 507 507 LEU LEU A . n 
A 1 508 PRO 508 508 508 PRO PRO A . n 
A 1 509 PRO 509 509 509 PRO PRO A . n 
A 1 510 LYS 510 510 510 LYS LYS A . n 
A 1 511 LEU 511 511 511 LEU LEU A . n 
A 1 512 ASP 512 512 512 ASP ASP A . n 
A 1 513 VAL 513 513 513 VAL VAL A . n 
A 1 514 PHE 514 514 514 PHE PHE A . n 
A 1 515 ASP 515 515 515 ASP ASP A . n 
A 1 516 ALA 516 516 516 ALA ALA A . n 
A 1 517 VAL 517 517 517 VAL VAL A . n 
A 1 518 VAL 518 518 518 VAL VAL A . n 
A 1 519 ALA 519 519 519 ALA ALA A . n 
A 1 520 ARG 520 520 ?   ?   ?   A . n 
A 1 521 HIS 521 521 ?   ?   ?   A . n 
A 1 522 SER 522 522 ?   ?   ?   A . n 
A 1 523 GLU 523 523 ?   ?   ?   A . n 
A 1 524 GLU 524 524 ?   ?   ?   A . n 
A 1 525 ASN 525 525 ?   ?   ?   A . n 
A 1 526 MET 526 526 ?   ?   ?   A . n 
A 1 527 ASP 527 527 ?   ?   ?   A . n 
A 1 528 LYS 528 528 ?   ?   ?   A . n 
A 1 529 THR 529 529 ?   ?   ?   A . n 
A 1 530 ILE 530 530 ?   ?   ?   A . n 
A 1 531 LEU 531 531 ?   ?   ?   A . n 
A 1 532 VAL 532 532 ?   ?   ?   A . n 
A 1 533 LYS 533 533 ?   ?   ?   A . n 
A 1 534 ASN 534 534 ?   ?   ?   A . n 
A 1 535 GLU 535 535 ?   ?   ?   A . n 
A 1 536 ASN 536 536 ?   ?   ?   A . n 
A 1 537 ILE 537 537 ?   ?   ?   A . n 
A 1 538 LYS 538 538 ?   ?   ?   A . n 
A 1 539 LEU 539 539 ?   ?   ?   A . n 
A 1 540 ASP 540 540 ?   ?   ?   A . n 
A 1 541 GLU 541 541 ?   ?   ?   A . n 
A 1 542 LEU 542 542 ?   ?   ?   A . n 
A 1 543 ALA 543 543 ?   ?   ?   A . n 
A 1 544 LEU 544 544 ?   ?   ?   A . n 
A 1 545 VAL 545 545 ?   ?   ?   A . n 
A 1 546 LYS 546 546 ?   ?   ?   A . n 
A 1 547 PRO 547 547 ?   ?   ?   A . n 
A 1 548 ARG 548 548 ?   ?   ?   A . n 
A 1 549 GLN 549 549 ?   ?   ?   A . n 
A 1 550 SER 550 550 ?   ?   ?   A . n 
A 1 551 MET 551 551 ?   ?   ?   A . n 
A 1 552 THR 552 552 ?   ?   ?   A . n 
A 1 553 LEU 553 553 ?   ?   ?   A . n 
A 1 554 SER 554 554 ?   ?   ?   A . n 
A 1 555 SER 555 555 ?   ?   ?   A . n 
A 1 556 THR 556 556 ?   ?   ?   A . n 
A 1 557 PHE 557 557 ?   ?   ?   A . n 
A 1 558 THR 558 558 ?   ?   ?   A . n 
A 1 559 ASN 559 559 ?   ?   ?   A . n 
A 1 560 LYS 560 560 ?   ?   ?   A . n 
A 1 561 GLU 561 561 ?   ?   ?   A . n 
A 1 562 ALA 562 562 ?   ?   ?   A . n 
A 1 563 PHE 563 563 ?   ?   ?   A . n 
A 1 564 LEU 564 564 ?   ?   ?   A . n 
A 1 565 ASP 565 565 ?   ?   ?   A . n 
A 1 566 VAL 566 566 ?   ?   ?   A . n 
A 1 567 ASP 567 567 ?   ?   ?   A . n 
A 1 568 SER 568 568 ?   ?   ?   A . n 
A 1 569 SER 569 569 ?   ?   ?   A . n 
A 1 570 PRO 570 570 ?   ?   ?   A . n 
A 1 571 GLU 571 571 ?   ?   ?   A . n 
A 1 572 GLY 572 572 ?   ?   ?   A . n 
A 1 573 SER 573 573 ?   ?   ?   A . n 
A 1 574 GLY 574 574 ?   ?   ?   A . n 
A 1 575 THR 575 575 ?   ?   ?   A . n 
A 1 576 GLU 576 576 ?   ?   ?   A . n 
A 1 577 ASP 577 577 ?   ?   ?   A . n 
A 1 578 ASN 578 578 ?   ?   ?   A . n 
A 1 579 LEU 579 579 ?   ?   ?   A . n 
A 1 580 GLN 580 580 ?   ?   ?   A . n 
A 1 581 ALA 581 581 ?   ?   ?   A . n 
A 1 582 ALA 582 582 ?   ?   ?   A . n 
A 1 583 ALA 583 583 ?   ?   ?   A . n 
A 1 584 GLY 584 584 ?   ?   ?   A . n 
A 1 585 GLY 585 585 ?   ?   ?   A . n 
A 1 586 SER 586 586 ?   ?   ?   A . n 
A 1 587 TRP 587 587 ?   ?   ?   A . n 
A 1 588 SER 588 588 ?   ?   ?   A . n 
A 1 589 HIS 589 589 ?   ?   ?   A . n 
A 1 590 PRO 590 590 ?   ?   ?   A . n 
A 1 591 GLN 591 591 ?   ?   ?   A . n 
A 1 592 PHE 592 592 ?   ?   ?   A . n 
A 1 593 GLU 593 593 ?   ?   ?   A . n 
A 1 594 LYS 594 594 ?   ?   ?   A . n 
A 1 595 GLY 595 595 ?   ?   ?   A . n 
A 1 596 GLY 596 596 ?   ?   ?   A . n 
A 1 597 GLY 597 597 ?   ?   ?   A . n 
A 1 598 SER 598 598 ?   ?   ?   A . n 
A 1 599 GLY 599 599 ?   ?   ?   A . n 
A 1 600 GLY 600 600 ?   ?   ?   A . n 
A 1 601 GLY 601 601 ?   ?   ?   A . n 
A 1 602 SER 602 602 ?   ?   ?   A . n 
A 1 603 GLY 603 603 ?   ?   ?   A . n 
A 1 604 GLY 604 604 ?   ?   ?   A . n 
A 1 605 SER 605 605 ?   ?   ?   A . n 
A 1 606 ALA 606 606 ?   ?   ?   A . n 
A 1 607 TRP 607 607 ?   ?   ?   A . n 
A 1 608 SER 608 608 ?   ?   ?   A . n 
A 1 609 HIS 609 609 ?   ?   ?   A . n 
A 1 610 PRO 610 610 ?   ?   ?   A . n 
A 1 611 GLN 611 611 ?   ?   ?   A . n 
A 1 612 PHE 612 612 ?   ?   ?   A . n 
A 1 613 GLU 613 613 ?   ?   ?   A . n 
A 1 614 LYS 614 614 ?   ?   ?   A . n 
# 
_pdbx_nonpoly_scheme.asym_id         B 
_pdbx_nonpoly_scheme.entity_id       2 
_pdbx_nonpoly_scheme.mon_id          A1AOW 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     801 
_pdbx_nonpoly_scheme.auth_seq_num    801 
_pdbx_nonpoly_scheme.pdb_mon_id      A1AOW 
_pdbx_nonpoly_scheme.auth_mon_id     LIG 
_pdbx_nonpoly_scheme.pdb_strand_id   A 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BFK 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BFK 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BFK 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BFK 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.003 ? 3939 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.661 ? 5381 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.341 ? 537  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.042 ? 624  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.005 ? 649  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9BFK 
_struct.title                        'Cryo-EM structure of human CHT1 in the ML352 bound state' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BFK 
_struct_keywords.text            'Choline transporter, TRANSPORT PROTEIN' 
_struct_keywords.pdbx_keywords   'TRANSPORT PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    SC5A7_HUMAN 
_struct_ref.pdbx_db_accession          Q9GZV3 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MAFHVEGLIAIIVFYLLILLVGIWAAWRTKNSGSAEERSEAIIVGGRDIGLLVGGFTMTATWVGGGYINGTAEAVYVPGY
GLAWAQAPIGYSLSLILGGLFFAKPMRSKGYVTMLDPFQQIYGKRMGGLLFIPALMGEMFWAAAIFSALGATISVIIDVD
MHISVIISALIATLYTLVGGLYSVAYTDVVQLFCIFVGLWISVPFALSHPAVADIGFTAVHAKYQKPWLGTVDSSEVYSW
LDSFLLLMLGGIPWQAYFQRVLSSSSATYAQVLSFLAAFGCLVMAIPAILIGAIGASTDWNQTAYGLPDPKTTEEADMIL
PIVLQYLCPVYISFFGLGAVSAAVMSSADSSILSASSMFARNIYQLSFRQNASDKEIVWVMRITVFVFGASATAMALLTK
TVYGLWYLSSDLVYIVIFPQLLCVLFVKGTNTYGAVAGYVSGLFLRITGGEPYLYLQPLIFYPGYYPDDNGIYNQKFPFK
TLAMVTSFLTNICISYLAKYLFESGTLPPKLDVFDAVVARHSEENMDKTILVKNENIKLDELALVKPRQSMTLSSTFTNK
EAFLDVDSSPEGSGTEDNLQ
;
_struct_ref.pdbx_align_begin           1 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9BFK 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 1 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 580 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             Q9GZV3 
_struct_ref_seq.db_align_beg                  1 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  580 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       1 
_struct_ref_seq.pdbx_auth_seq_align_end       580 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BFK ALA A 581 ? UNP Q9GZV3 ? ? 'expression tag' 581 1  
1 9BFK ALA A 582 ? UNP Q9GZV3 ? ? 'expression tag' 582 2  
1 9BFK ALA A 583 ? UNP Q9GZV3 ? ? 'expression tag' 583 3  
1 9BFK GLY A 584 ? UNP Q9GZV3 ? ? 'expression tag' 584 4  
1 9BFK GLY A 585 ? UNP Q9GZV3 ? ? 'expression tag' 585 5  
1 9BFK SER A 586 ? UNP Q9GZV3 ? ? 'expression tag' 586 6  
1 9BFK TRP A 587 ? UNP Q9GZV3 ? ? 'expression tag' 587 7  
1 9BFK SER A 588 ? UNP Q9GZV3 ? ? 'expression tag' 588 8  
1 9BFK HIS A 589 ? UNP Q9GZV3 ? ? 'expression tag' 589 9  
1 9BFK PRO A 590 ? UNP Q9GZV3 ? ? 'expression tag' 590 10 
1 9BFK GLN A 591 ? UNP Q9GZV3 ? ? 'expression tag' 591 11 
1 9BFK PHE A 592 ? UNP Q9GZV3 ? ? 'expression tag' 592 12 
1 9BFK GLU A 593 ? UNP Q9GZV3 ? ? 'expression tag' 593 13 
1 9BFK LYS A 594 ? UNP Q9GZV3 ? ? 'expression tag' 594 14 
1 9BFK GLY A 595 ? UNP Q9GZV3 ? ? 'expression tag' 595 15 
1 9BFK GLY A 596 ? UNP Q9GZV3 ? ? 'expression tag' 596 16 
1 9BFK GLY A 597 ? UNP Q9GZV3 ? ? 'expression tag' 597 17 
1 9BFK SER A 598 ? UNP Q9GZV3 ? ? 'expression tag' 598 18 
1 9BFK GLY A 599 ? UNP Q9GZV3 ? ? 'expression tag' 599 19 
1 9BFK GLY A 600 ? UNP Q9GZV3 ? ? 'expression tag' 600 20 
1 9BFK GLY A 601 ? UNP Q9GZV3 ? ? 'expression tag' 601 21 
1 9BFK SER A 602 ? UNP Q9GZV3 ? ? 'expression tag' 602 22 
1 9BFK GLY A 603 ? UNP Q9GZV3 ? ? 'expression tag' 603 23 
1 9BFK GLY A 604 ? UNP Q9GZV3 ? ? 'expression tag' 604 24 
1 9BFK SER A 605 ? UNP Q9GZV3 ? ? 'expression tag' 605 25 
1 9BFK ALA A 606 ? UNP Q9GZV3 ? ? 'expression tag' 606 26 
1 9BFK TRP A 607 ? UNP Q9GZV3 ? ? 'expression tag' 607 27 
1 9BFK SER A 608 ? UNP Q9GZV3 ? ? 'expression tag' 608 28 
1 9BFK HIS A 609 ? UNP Q9GZV3 ? ? 'expression tag' 609 29 
1 9BFK PRO A 610 ? UNP Q9GZV3 ? ? 'expression tag' 610 30 
1 9BFK GLN A 611 ? UNP Q9GZV3 ? ? 'expression tag' 611 31 
1 9BFK PHE A 612 ? UNP Q9GZV3 ? ? 'expression tag' 612 32 
1 9BFK GLU A 613 ? UNP Q9GZV3 ? ? 'expression tag' 613 33 
1 9BFK LYS A 614 ? UNP Q9GZV3 ? ? 'expression tag' 614 34 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0 
_pdbx_struct_oper_list.matrix[1][2]         0.0 
_pdbx_struct_oper_list.matrix[1][3]         0.0 
_pdbx_struct_oper_list.vector[1]            0.0 
_pdbx_struct_oper_list.matrix[2][1]         0.0 
_pdbx_struct_oper_list.matrix[2][2]         1.0 
_pdbx_struct_oper_list.matrix[2][3]         0.0 
_pdbx_struct_oper_list.vector[2]            0.0 
_pdbx_struct_oper_list.matrix[3][1]         0.0 
_pdbx_struct_oper_list.matrix[3][2]         0.0 
_pdbx_struct_oper_list.matrix[3][3]         1.0 
_pdbx_struct_oper_list.vector[3]            0.0 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 HIS A 4   ? THR A 29  ? HIS A 4   THR A 29  1 ? 26 
HELX_P HELX_P2  AA2 ILE A 49  ? VAL A 63  ? ILE A 49  VAL A 63  1 ? 15 
HELX_P HELX_P3  AA3 GLY A 64  ? VAL A 77  ? GLY A 64  VAL A 77  1 ? 14 
HELX_P HELX_P4  AA4 GLY A 81  ? ALA A 85  ? GLY A 81  ALA A 85  5 ? 5  
HELX_P HELX_P5  AA5 GLN A 86  ? PHE A 102 ? GLN A 86  PHE A 102 1 ? 17 
HELX_P HELX_P6  AA6 PHE A 102 ? LYS A 109 ? PHE A 102 LYS A 109 1 ? 8  
HELX_P HELX_P7  AA7 LEU A 115 ? ASP A 158 ? LEU A 115 ASP A 158 1 ? 44 
HELX_P HELX_P8  AA8 ASP A 160 ? VAL A 178 ? ASP A 160 VAL A 178 1 ? 19 
HELX_P HELX_P9  AA9 TYR A 186 ? SER A 208 ? TYR A 186 SER A 208 1 ? 23 
HELX_P HELX_P10 AB1 GLY A 216 ? HIS A 221 ? GLY A 216 HIS A 221 1 ? 6  
HELX_P HELX_P11 AB2 GLU A 236 ? GLY A 251 ? GLU A 236 GLY A 251 1 ? 16 
HELX_P HELX_P12 AB3 TRP A 254 ? SER A 264 ? TRP A 254 SER A 264 1 ? 11 
HELX_P HELX_P13 AB4 SER A 266 ? THR A 298 ? SER A 266 THR A 298 1 ? 33 
HELX_P HELX_P14 AB5 GLU A 315 ? ASP A 317 ? GLU A 315 ASP A 317 5 ? 3  
HELX_P HELX_P15 AB6 MET A 318 ? LEU A 327 ? MET A 318 LEU A 327 1 ? 10 
HELX_P HELX_P16 AB7 PRO A 329 ? SER A 347 ? PRO A 329 SER A 347 1 ? 19 
HELX_P HELX_P17 AB8 ASP A 349 ? ASN A 362 ? ASP A 349 ASN A 362 1 ? 14 
HELX_P HELX_P18 AB9 ASP A 374 ? THR A 399 ? ASP A 374 THR A 399 1 ? 26 
HELX_P HELX_P19 AC1 VAL A 402 ? VAL A 416 ? VAL A 402 VAL A 416 1 ? 15 
HELX_P HELX_P20 AC2 VAL A 416 ? VAL A 427 ? VAL A 416 VAL A 427 1 ? 12 
HELX_P HELX_P21 AC3 ASN A 431 ? THR A 448 ? ASN A 431 THR A 448 1 ? 18 
HELX_P HELX_P22 AC4 PRO A 478 ? SER A 504 ? PRO A 478 SER A 504 1 ? 27 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LEU 
_struct_mon_prot_cis.label_seq_id           307 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LEU 
_struct_mon_prot_cis.auth_seq_id            307 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    308 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     308 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       1.57 
# 
_struct_sheet.id               AA1 
_struct_sheet.type             ? 
_struct_sheet.number_strands   2 
_struct_sheet.details          ? 
# 
_struct_sheet_order.sheet_id     AA1 
_struct_sheet_order.range_id_1   1 
_struct_sheet_order.range_id_2   2 
_struct_sheet_order.offset       ? 
_struct_sheet_order.sense        anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 TYR A 466 ? PRO A 467 ? TYR A 466 PRO A 467 
AA1 2 TYR A 473 ? ASN A 474 ? TYR A 473 ASN A 474 
# 
_pdbx_struct_sheet_hbond.sheet_id                AA1 
_pdbx_struct_sheet_hbond.range_id_1              1 
_pdbx_struct_sheet_hbond.range_id_2              2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id   N 
_pdbx_struct_sheet_hbond.range_1_label_comp_id   TYR 
_pdbx_struct_sheet_hbond.range_1_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_1_label_seq_id    466 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id    N 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id    TYR 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id     466 
_pdbx_struct_sheet_hbond.range_2_label_atom_id   O 
_pdbx_struct_sheet_hbond.range_2_label_comp_id   ASN 
_pdbx_struct_sheet_hbond.range_2_label_asym_id   A 
_pdbx_struct_sheet_hbond.range_2_label_seq_id    474 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code    ? 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id    O 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id    ASN 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id    A 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id     474 
# 
_pdbx_entry_details.entry_id                   9BFK 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   N 
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9BFK 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9BFK 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  2.85 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               317376 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.4 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 'ORGANELLE OR CELLULAR COMPONENT' 
_em_entity_assembly.name                 'human CHT1 in the ML352 bound state' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9BFK 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             800 
_em_imaging.nominal_defocus_max             1800 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9BFK 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9BFK 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 1   ? A MET 1   
2   1 Y 1 A LYS 30  ? A LYS 30  
3   1 Y 1 A ASN 31  ? A ASN 31  
4   1 Y 1 A SER 32  ? A SER 32  
5   1 Y 1 A GLY 33  ? A GLY 33  
6   1 Y 1 A SER 34  ? A SER 34  
7   1 Y 1 A ALA 35  ? A ALA 35  
8   1 Y 1 A GLU 36  ? A GLU 36  
9   1 Y 1 A GLU 37  ? A GLU 37  
10  1 Y 1 A ARG 38  ? A ARG 38  
11  1 Y 1 A SER 39  ? A SER 39  
12  1 Y 1 A GLU 40  ? A GLU 40  
13  1 Y 1 A ALA 41  ? A ALA 41  
14  1 Y 1 A ILE 42  ? A ILE 42  
15  1 Y 1 A ILE 43  ? A ILE 43  
16  1 Y 1 A VAL 44  ? A VAL 44  
17  1 Y 1 A GLY 45  ? A GLY 45  
18  1 Y 1 A GLY 46  ? A GLY 46  
19  1 Y 1 A GLY 180 ? A GLY 180 
20  1 Y 1 A LEU 181 ? A LEU 181 
21  1 Y 1 A TYR 182 ? A TYR 182 
22  1 Y 1 A ARG 369 ? A ARG 369 
23  1 Y 1 A GLN 370 ? A GLN 370 
24  1 Y 1 A ASN 371 ? A ASN 371 
25  1 Y 1 A ALA 372 ? A ALA 372 
26  1 Y 1 A ARG 520 ? A ARG 520 
27  1 Y 1 A HIS 521 ? A HIS 521 
28  1 Y 1 A SER 522 ? A SER 522 
29  1 Y 1 A GLU 523 ? A GLU 523 
30  1 Y 1 A GLU 524 ? A GLU 524 
31  1 Y 1 A ASN 525 ? A ASN 525 
32  1 Y 1 A MET 526 ? A MET 526 
33  1 Y 1 A ASP 527 ? A ASP 527 
34  1 Y 1 A LYS 528 ? A LYS 528 
35  1 Y 1 A THR 529 ? A THR 529 
36  1 Y 1 A ILE 530 ? A ILE 530 
37  1 Y 1 A LEU 531 ? A LEU 531 
38  1 Y 1 A VAL 532 ? A VAL 532 
39  1 Y 1 A LYS 533 ? A LYS 533 
40  1 Y 1 A ASN 534 ? A ASN 534 
41  1 Y 1 A GLU 535 ? A GLU 535 
42  1 Y 1 A ASN 536 ? A ASN 536 
43  1 Y 1 A ILE 537 ? A ILE 537 
44  1 Y 1 A LYS 538 ? A LYS 538 
45  1 Y 1 A LEU 539 ? A LEU 539 
46  1 Y 1 A ASP 540 ? A ASP 540 
47  1 Y 1 A GLU 541 ? A GLU 541 
48  1 Y 1 A LEU 542 ? A LEU 542 
49  1 Y 1 A ALA 543 ? A ALA 543 
50  1 Y 1 A LEU 544 ? A LEU 544 
51  1 Y 1 A VAL 545 ? A VAL 545 
52  1 Y 1 A LYS 546 ? A LYS 546 
53  1 Y 1 A PRO 547 ? A PRO 547 
54  1 Y 1 A ARG 548 ? A ARG 548 
55  1 Y 1 A GLN 549 ? A GLN 549 
56  1 Y 1 A SER 550 ? A SER 550 
57  1 Y 1 A MET 551 ? A MET 551 
58  1 Y 1 A THR 552 ? A THR 552 
59  1 Y 1 A LEU 553 ? A LEU 553 
60  1 Y 1 A SER 554 ? A SER 554 
61  1 Y 1 A SER 555 ? A SER 555 
62  1 Y 1 A THR 556 ? A THR 556 
63  1 Y 1 A PHE 557 ? A PHE 557 
64  1 Y 1 A THR 558 ? A THR 558 
65  1 Y 1 A ASN 559 ? A ASN 559 
66  1 Y 1 A LYS 560 ? A LYS 560 
67  1 Y 1 A GLU 561 ? A GLU 561 
68  1 Y 1 A ALA 562 ? A ALA 562 
69  1 Y 1 A PHE 563 ? A PHE 563 
70  1 Y 1 A LEU 564 ? A LEU 564 
71  1 Y 1 A ASP 565 ? A ASP 565 
72  1 Y 1 A VAL 566 ? A VAL 566 
73  1 Y 1 A ASP 567 ? A ASP 567 
74  1 Y 1 A SER 568 ? A SER 568 
75  1 Y 1 A SER 569 ? A SER 569 
76  1 Y 1 A PRO 570 ? A PRO 570 
77  1 Y 1 A GLU 571 ? A GLU 571 
78  1 Y 1 A GLY 572 ? A GLY 572 
79  1 Y 1 A SER 573 ? A SER 573 
80  1 Y 1 A GLY 574 ? A GLY 574 
81  1 Y 1 A THR 575 ? A THR 575 
82  1 Y 1 A GLU 576 ? A GLU 576 
83  1 Y 1 A ASP 577 ? A ASP 577 
84  1 Y 1 A ASN 578 ? A ASN 578 
85  1 Y 1 A LEU 579 ? A LEU 579 
86  1 Y 1 A GLN 580 ? A GLN 580 
87  1 Y 1 A ALA 581 ? A ALA 581 
88  1 Y 1 A ALA 582 ? A ALA 582 
89  1 Y 1 A ALA 583 ? A ALA 583 
90  1 Y 1 A GLY 584 ? A GLY 584 
91  1 Y 1 A GLY 585 ? A GLY 585 
92  1 Y 1 A SER 586 ? A SER 586 
93  1 Y 1 A TRP 587 ? A TRP 587 
94  1 Y 1 A SER 588 ? A SER 588 
95  1 Y 1 A HIS 589 ? A HIS 589 
96  1 Y 1 A PRO 590 ? A PRO 590 
97  1 Y 1 A GLN 591 ? A GLN 591 
98  1 Y 1 A PHE 592 ? A PHE 592 
99  1 Y 1 A GLU 593 ? A GLU 593 
100 1 Y 1 A LYS 594 ? A LYS 594 
101 1 Y 1 A GLY 595 ? A GLY 595 
102 1 Y 1 A GLY 596 ? A GLY 596 
103 1 Y 1 A GLY 597 ? A GLY 597 
104 1 Y 1 A SER 598 ? A SER 598 
105 1 Y 1 A GLY 599 ? A GLY 599 
106 1 Y 1 A GLY 600 ? A GLY 600 
107 1 Y 1 A GLY 601 ? A GLY 601 
108 1 Y 1 A SER 602 ? A SER 602 
109 1 Y 1 A GLY 603 ? A GLY 603 
110 1 Y 1 A GLY 604 ? A GLY 604 
111 1 Y 1 A SER 605 ? A SER 605 
112 1 Y 1 A ALA 606 ? A ALA 606 
113 1 Y 1 A TRP 607 ? A TRP 607 
114 1 Y 1 A SER 608 ? A SER 608 
115 1 Y 1 A HIS 609 ? A HIS 609 
116 1 Y 1 A PRO 610 ? A PRO 610 
117 1 Y 1 A GLN 611 ? A GLN 611 
118 1 Y 1 A PHE 612 ? A PHE 612 
119 1 Y 1 A GLU 613 ? A GLU 613 
120 1 Y 1 A LYS 614 ? A LYS 614 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AOW C10  C N N 1   
A1AOW C13  C N N 2   
A1AOW C15  C Y N 3   
A1AOW C17  C Y N 4   
A1AOW C20  C N N 5   
A1AOW C21  C N N 6   
A1AOW C22  C Y N 7   
A1AOW C24  C Y N 8   
A1AOW C26  C N N 9   
A1AOW C28  C N N 10  
A1AOW C08  C N N 11  
A1AOW C09  C N N 12  
A1AOW C11  C N N 13  
A1AOW C12  C N N 14  
A1AOW C14  C Y N 15  
A1AOW C16  C Y N 16  
A1AOW C18  C Y N 17  
A1AOW C19  C Y N 18  
A1AOW C23  C N N 19  
A1AOW C25  C Y N 20  
A1AOW C27  C N N 21  
A1AOW N05  N N N 22  
A1AOW N06  N N N 23  
A1AOW N07  N Y N 24  
A1AOW O01  O N N 25  
A1AOW O02  O N N 26  
A1AOW O03  O Y N 27  
A1AOW O04  O N N 28  
A1AOW H1   H N N 29  
A1AOW H2   H N N 30  
A1AOW H3   H N N 31  
A1AOW H4   H N N 32  
A1AOW H5   H N N 33  
A1AOW H6   H N N 34  
A1AOW H7   H N N 35  
A1AOW H8   H N N 36  
A1AOW H9   H N N 37  
A1AOW H10  H N N 38  
A1AOW H11  H N N 39  
A1AOW H12  H N N 40  
A1AOW H13  H N N 41  
A1AOW H14  H N N 42  
A1AOW H15  H N N 43  
A1AOW H16  H N N 44  
A1AOW H17  H N N 45  
A1AOW H18  H N N 46  
A1AOW H19  H N N 47  
A1AOW H20  H N N 48  
A1AOW H21  H N N 49  
A1AOW H22  H N N 50  
A1AOW H23  H N N 51  
A1AOW H24  H N N 52  
A1AOW H25  H N N 53  
A1AOW H26  H N N 54  
A1AOW H27  H N N 55  
A1AOW H28  H N N 56  
A1AOW H30  H N N 57  
ALA   N    N N N 58  
ALA   CA   C N S 59  
ALA   C    C N N 60  
ALA   O    O N N 61  
ALA   CB   C N N 62  
ALA   OXT  O N N 63  
ALA   H    H N N 64  
ALA   H2   H N N 65  
ALA   HA   H N N 66  
ALA   HB1  H N N 67  
ALA   HB2  H N N 68  
ALA   HB3  H N N 69  
ALA   HXT  H N N 70  
ARG   N    N N N 71  
ARG   CA   C N S 72  
ARG   C    C N N 73  
ARG   O    O N N 74  
ARG   CB   C N N 75  
ARG   CG   C N N 76  
ARG   CD   C N N 77  
ARG   NE   N N N 78  
ARG   CZ   C N N 79  
ARG   NH1  N N N 80  
ARG   NH2  N N N 81  
ARG   OXT  O N N 82  
ARG   H    H N N 83  
ARG   H2   H N N 84  
ARG   HA   H N N 85  
ARG   HB2  H N N 86  
ARG   HB3  H N N 87  
ARG   HG2  H N N 88  
ARG   HG3  H N N 89  
ARG   HD2  H N N 90  
ARG   HD3  H N N 91  
ARG   HE   H N N 92  
ARG   HH11 H N N 93  
ARG   HH12 H N N 94  
ARG   HH21 H N N 95  
ARG   HH22 H N N 96  
ARG   HXT  H N N 97  
ASN   N    N N N 98  
ASN   CA   C N S 99  
ASN   C    C N N 100 
ASN   O    O N N 101 
ASN   CB   C N N 102 
ASN   CG   C N N 103 
ASN   OD1  O N N 104 
ASN   ND2  N N N 105 
ASN   OXT  O N N 106 
ASN   H    H N N 107 
ASN   H2   H N N 108 
ASN   HA   H N N 109 
ASN   HB2  H N N 110 
ASN   HB3  H N N 111 
ASN   HD21 H N N 112 
ASN   HD22 H N N 113 
ASN   HXT  H N N 114 
ASP   N    N N N 115 
ASP   CA   C N S 116 
ASP   C    C N N 117 
ASP   O    O N N 118 
ASP   CB   C N N 119 
ASP   CG   C N N 120 
ASP   OD1  O N N 121 
ASP   OD2  O N N 122 
ASP   OXT  O N N 123 
ASP   H    H N N 124 
ASP   H2   H N N 125 
ASP   HA   H N N 126 
ASP   HB2  H N N 127 
ASP   HB3  H N N 128 
ASP   HD2  H N N 129 
ASP   HXT  H N N 130 
CYS   N    N N N 131 
CYS   CA   C N R 132 
CYS   C    C N N 133 
CYS   O    O N N 134 
CYS   CB   C N N 135 
CYS   SG   S N N 136 
CYS   OXT  O N N 137 
CYS   H    H N N 138 
CYS   H2   H N N 139 
CYS   HA   H N N 140 
CYS   HB2  H N N 141 
CYS   HB3  H N N 142 
CYS   HG   H N N 143 
CYS   HXT  H N N 144 
GLN   N    N N N 145 
GLN   CA   C N S 146 
GLN   C    C N N 147 
GLN   O    O N N 148 
GLN   CB   C N N 149 
GLN   CG   C N N 150 
GLN   CD   C N N 151 
GLN   OE1  O N N 152 
GLN   NE2  N N N 153 
GLN   OXT  O N N 154 
GLN   H    H N N 155 
GLN   H2   H N N 156 
GLN   HA   H N N 157 
GLN   HB2  H N N 158 
GLN   HB3  H N N 159 
GLN   HG2  H N N 160 
GLN   HG3  H N N 161 
GLN   HE21 H N N 162 
GLN   HE22 H N N 163 
GLN   HXT  H N N 164 
GLU   N    N N N 165 
GLU   CA   C N S 166 
GLU   C    C N N 167 
GLU   O    O N N 168 
GLU   CB   C N N 169 
GLU   CG   C N N 170 
GLU   CD   C N N 171 
GLU   OE1  O N N 172 
GLU   OE2  O N N 173 
GLU   OXT  O N N 174 
GLU   H    H N N 175 
GLU   H2   H N N 176 
GLU   HA   H N N 177 
GLU   HB2  H N N 178 
GLU   HB3  H N N 179 
GLU   HG2  H N N 180 
GLU   HG3  H N N 181 
GLU   HE2  H N N 182 
GLU   HXT  H N N 183 
GLY   N    N N N 184 
GLY   CA   C N N 185 
GLY   C    C N N 186 
GLY   O    O N N 187 
GLY   OXT  O N N 188 
GLY   H    H N N 189 
GLY   H2   H N N 190 
GLY   HA2  H N N 191 
GLY   HA3  H N N 192 
GLY   HXT  H N N 193 
HIS   N    N N N 194 
HIS   CA   C N S 195 
HIS   C    C N N 196 
HIS   O    O N N 197 
HIS   CB   C N N 198 
HIS   CG   C Y N 199 
HIS   ND1  N Y N 200 
HIS   CD2  C Y N 201 
HIS   CE1  C Y N 202 
HIS   NE2  N Y N 203 
HIS   OXT  O N N 204 
HIS   H    H N N 205 
HIS   H2   H N N 206 
HIS   HA   H N N 207 
HIS   HB2  H N N 208 
HIS   HB3  H N N 209 
HIS   HD1  H N N 210 
HIS   HD2  H N N 211 
HIS   HE1  H N N 212 
HIS   HE2  H N N 213 
HIS   HXT  H N N 214 
ILE   N    N N N 215 
ILE   CA   C N S 216 
ILE   C    C N N 217 
ILE   O    O N N 218 
ILE   CB   C N S 219 
ILE   CG1  C N N 220 
ILE   CG2  C N N 221 
ILE   CD1  C N N 222 
ILE   OXT  O N N 223 
ILE   H    H N N 224 
ILE   H2   H N N 225 
ILE   HA   H N N 226 
ILE   HB   H N N 227 
ILE   HG12 H N N 228 
ILE   HG13 H N N 229 
ILE   HG21 H N N 230 
ILE   HG22 H N N 231 
ILE   HG23 H N N 232 
ILE   HD11 H N N 233 
ILE   HD12 H N N 234 
ILE   HD13 H N N 235 
ILE   HXT  H N N 236 
LEU   N    N N N 237 
LEU   CA   C N S 238 
LEU   C    C N N 239 
LEU   O    O N N 240 
LEU   CB   C N N 241 
LEU   CG   C N N 242 
LEU   CD1  C N N 243 
LEU   CD2  C N N 244 
LEU   OXT  O N N 245 
LEU   H    H N N 246 
LEU   H2   H N N 247 
LEU   HA   H N N 248 
LEU   HB2  H N N 249 
LEU   HB3  H N N 250 
LEU   HG   H N N 251 
LEU   HD11 H N N 252 
LEU   HD12 H N N 253 
LEU   HD13 H N N 254 
LEU   HD21 H N N 255 
LEU   HD22 H N N 256 
LEU   HD23 H N N 257 
LEU   HXT  H N N 258 
LYS   N    N N N 259 
LYS   CA   C N S 260 
LYS   C    C N N 261 
LYS   O    O N N 262 
LYS   CB   C N N 263 
LYS   CG   C N N 264 
LYS   CD   C N N 265 
LYS   CE   C N N 266 
LYS   NZ   N N N 267 
LYS   OXT  O N N 268 
LYS   H    H N N 269 
LYS   H2   H N N 270 
LYS   HA   H N N 271 
LYS   HB2  H N N 272 
LYS   HB3  H N N 273 
LYS   HG2  H N N 274 
LYS   HG3  H N N 275 
LYS   HD2  H N N 276 
LYS   HD3  H N N 277 
LYS   HE2  H N N 278 
LYS   HE3  H N N 279 
LYS   HZ1  H N N 280 
LYS   HZ2  H N N 281 
LYS   HZ3  H N N 282 
LYS   HXT  H N N 283 
MET   N    N N N 284 
MET   CA   C N S 285 
MET   C    C N N 286 
MET   O    O N N 287 
MET   CB   C N N 288 
MET   CG   C N N 289 
MET   SD   S N N 290 
MET   CE   C N N 291 
MET   OXT  O N N 292 
MET   H    H N N 293 
MET   H2   H N N 294 
MET   HA   H N N 295 
MET   HB2  H N N 296 
MET   HB3  H N N 297 
MET   HG2  H N N 298 
MET   HG3  H N N 299 
MET   HE1  H N N 300 
MET   HE2  H N N 301 
MET   HE3  H N N 302 
MET   HXT  H N N 303 
PHE   N    N N N 304 
PHE   CA   C N S 305 
PHE   C    C N N 306 
PHE   O    O N N 307 
PHE   CB   C N N 308 
PHE   CG   C Y N 309 
PHE   CD1  C Y N 310 
PHE   CD2  C Y N 311 
PHE   CE1  C Y N 312 
PHE   CE2  C Y N 313 
PHE   CZ   C Y N 314 
PHE   OXT  O N N 315 
PHE   H    H N N 316 
PHE   H2   H N N 317 
PHE   HA   H N N 318 
PHE   HB2  H N N 319 
PHE   HB3  H N N 320 
PHE   HD1  H N N 321 
PHE   HD2  H N N 322 
PHE   HE1  H N N 323 
PHE   HE2  H N N 324 
PHE   HZ   H N N 325 
PHE   HXT  H N N 326 
PRO   N    N N N 327 
PRO   CA   C N S 328 
PRO   C    C N N 329 
PRO   O    O N N 330 
PRO   CB   C N N 331 
PRO   CG   C N N 332 
PRO   CD   C N N 333 
PRO   OXT  O N N 334 
PRO   H    H N N 335 
PRO   HA   H N N 336 
PRO   HB2  H N N 337 
PRO   HB3  H N N 338 
PRO   HG2  H N N 339 
PRO   HG3  H N N 340 
PRO   HD2  H N N 341 
PRO   HD3  H N N 342 
PRO   HXT  H N N 343 
SER   N    N N N 344 
SER   CA   C N S 345 
SER   C    C N N 346 
SER   O    O N N 347 
SER   CB   C N N 348 
SER   OG   O N N 349 
SER   OXT  O N N 350 
SER   H    H N N 351 
SER   H2   H N N 352 
SER   HA   H N N 353 
SER   HB2  H N N 354 
SER   HB3  H N N 355 
SER   HG   H N N 356 
SER   HXT  H N N 357 
THR   N    N N N 358 
THR   CA   C N S 359 
THR   C    C N N 360 
THR   O    O N N 361 
THR   CB   C N R 362 
THR   OG1  O N N 363 
THR   CG2  C N N 364 
THR   OXT  O N N 365 
THR   H    H N N 366 
THR   H2   H N N 367 
THR   HA   H N N 368 
THR   HB   H N N 369 
THR   HG1  H N N 370 
THR   HG21 H N N 371 
THR   HG22 H N N 372 
THR   HG23 H N N 373 
THR   HXT  H N N 374 
TRP   N    N N N 375 
TRP   CA   C N S 376 
TRP   C    C N N 377 
TRP   O    O N N 378 
TRP   CB   C N N 379 
TRP   CG   C Y N 380 
TRP   CD1  C Y N 381 
TRP   CD2  C Y N 382 
TRP   NE1  N Y N 383 
TRP   CE2  C Y N 384 
TRP   CE3  C Y N 385 
TRP   CZ2  C Y N 386 
TRP   CZ3  C Y N 387 
TRP   CH2  C Y N 388 
TRP   OXT  O N N 389 
TRP   H    H N N 390 
TRP   H2   H N N 391 
TRP   HA   H N N 392 
TRP   HB2  H N N 393 
TRP   HB3  H N N 394 
TRP   HD1  H N N 395 
TRP   HE1  H N N 396 
TRP   HE3  H N N 397 
TRP   HZ2  H N N 398 
TRP   HZ3  H N N 399 
TRP   HH2  H N N 400 
TRP   HXT  H N N 401 
TYR   N    N N N 402 
TYR   CA   C N S 403 
TYR   C    C N N 404 
TYR   O    O N N 405 
TYR   CB   C N N 406 
TYR   CG   C Y N 407 
TYR   CD1  C Y N 408 
TYR   CD2  C Y N 409 
TYR   CE1  C Y N 410 
TYR   CE2  C Y N 411 
TYR   CZ   C Y N 412 
TYR   OH   O N N 413 
TYR   OXT  O N N 414 
TYR   H    H N N 415 
TYR   H2   H N N 416 
TYR   HA   H N N 417 
TYR   HB2  H N N 418 
TYR   HB3  H N N 419 
TYR   HD1  H N N 420 
TYR   HD2  H N N 421 
TYR   HE1  H N N 422 
TYR   HE2  H N N 423 
TYR   HH   H N N 424 
TYR   HXT  H N N 425 
VAL   N    N N N 426 
VAL   CA   C N S 427 
VAL   C    C N N 428 
VAL   O    O N N 429 
VAL   CB   C N N 430 
VAL   CG1  C N N 431 
VAL   CG2  C N N 432 
VAL   OXT  O N N 433 
VAL   H    H N N 434 
VAL   H2   H N N 435 
VAL   HA   H N N 436 
VAL   HB   H N N 437 
VAL   HG11 H N N 438 
VAL   HG12 H N N 439 
VAL   HG13 H N N 440 
VAL   HG21 H N N 441 
VAL   HG22 H N N 442 
VAL   HG23 H N N 443 
VAL   HXT  H N N 444 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AOW C19 C18  doub Y N 1   
A1AOW C19 C17  sing Y N 2   
A1AOW C23 N06  sing N N 3   
A1AOW C23 C24  sing N N 4   
A1AOW C18 C16  sing Y N 5   
A1AOW N06 C21  sing N N 6   
A1AOW O04 C21  doub N N 7   
A1AOW C21 C17  sing N N 8   
A1AOW C17 C15  doub Y N 9   
A1AOW C28 O02  sing N N 10  
A1AOW C11 C09  sing N N 11  
A1AOW C11 N05  sing N N 12  
A1AOW C16 O02  sing N N 13  
A1AOW C16 C14  doub Y N 14  
A1AOW C09 C08  sing N N 15  
A1AOW C24 O03  sing Y N 16  
A1AOW C24 C25  doub Y N 17  
A1AOW C15 C14  sing Y N 18  
A1AOW C14 O01  sing N N 19  
A1AOW O03 N07  sing Y N 20  
A1AOW N05 C13  sing N N 21  
A1AOW N05 C12  sing N N 22  
A1AOW C25 C22  sing Y N 23  
A1AOW C08 O01  sing N N 24  
A1AOW C08 C10  sing N N 25  
A1AOW N07 C22  doub Y N 26  
A1AOW C22 C20  sing N N 27  
A1AOW C12 C10  sing N N 28  
A1AOW C20 C26  sing N N 29  
A1AOW C20 C27  sing N N 30  
A1AOW C10 H1   sing N N 31  
A1AOW C10 H2   sing N N 32  
A1AOW C13 H3   sing N N 33  
A1AOW C13 H4   sing N N 34  
A1AOW C13 H5   sing N N 35  
A1AOW C15 H6   sing N N 36  
A1AOW C20 H7   sing N N 37  
A1AOW C26 H8   sing N N 38  
A1AOW C26 H9   sing N N 39  
A1AOW C26 H10  sing N N 40  
A1AOW C28 H11  sing N N 41  
A1AOW C28 H12  sing N N 42  
A1AOW C28 H13  sing N N 43  
A1AOW C08 H14  sing N N 44  
A1AOW C09 H15  sing N N 45  
A1AOW C09 H16  sing N N 46  
A1AOW C11 H17  sing N N 47  
A1AOW C11 H18  sing N N 48  
A1AOW C12 H19  sing N N 49  
A1AOW C12 H20  sing N N 50  
A1AOW C18 H21  sing N N 51  
A1AOW C19 H22  sing N N 52  
A1AOW C23 H23  sing N N 53  
A1AOW C23 H24  sing N N 54  
A1AOW C25 H25  sing N N 55  
A1AOW C27 H26  sing N N 56  
A1AOW C27 H27  sing N N 57  
A1AOW C27 H28  sing N N 58  
A1AOW N06 H30  sing N N 59  
ALA   N   CA   sing N N 60  
ALA   N   H    sing N N 61  
ALA   N   H2   sing N N 62  
ALA   CA  C    sing N N 63  
ALA   CA  CB   sing N N 64  
ALA   CA  HA   sing N N 65  
ALA   C   O    doub N N 66  
ALA   C   OXT  sing N N 67  
ALA   CB  HB1  sing N N 68  
ALA   CB  HB2  sing N N 69  
ALA   CB  HB3  sing N N 70  
ALA   OXT HXT  sing N N 71  
ARG   N   CA   sing N N 72  
ARG   N   H    sing N N 73  
ARG   N   H2   sing N N 74  
ARG   CA  C    sing N N 75  
ARG   CA  CB   sing N N 76  
ARG   CA  HA   sing N N 77  
ARG   C   O    doub N N 78  
ARG   C   OXT  sing N N 79  
ARG   CB  CG   sing N N 80  
ARG   CB  HB2  sing N N 81  
ARG   CB  HB3  sing N N 82  
ARG   CG  CD   sing N N 83  
ARG   CG  HG2  sing N N 84  
ARG   CG  HG3  sing N N 85  
ARG   CD  NE   sing N N 86  
ARG   CD  HD2  sing N N 87  
ARG   CD  HD3  sing N N 88  
ARG   NE  CZ   sing N N 89  
ARG   NE  HE   sing N N 90  
ARG   CZ  NH1  sing N N 91  
ARG   CZ  NH2  doub N N 92  
ARG   NH1 HH11 sing N N 93  
ARG   NH1 HH12 sing N N 94  
ARG   NH2 HH21 sing N N 95  
ARG   NH2 HH22 sing N N 96  
ARG   OXT HXT  sing N N 97  
ASN   N   CA   sing N N 98  
ASN   N   H    sing N N 99  
ASN   N   H2   sing N N 100 
ASN   CA  C    sing N N 101 
ASN   CA  CB   sing N N 102 
ASN   CA  HA   sing N N 103 
ASN   C   O    doub N N 104 
ASN   C   OXT  sing N N 105 
ASN   CB  CG   sing N N 106 
ASN   CB  HB2  sing N N 107 
ASN   CB  HB3  sing N N 108 
ASN   CG  OD1  doub N N 109 
ASN   CG  ND2  sing N N 110 
ASN   ND2 HD21 sing N N 111 
ASN   ND2 HD22 sing N N 112 
ASN   OXT HXT  sing N N 113 
ASP   N   CA   sing N N 114 
ASP   N   H    sing N N 115 
ASP   N   H2   sing N N 116 
ASP   CA  C    sing N N 117 
ASP   CA  CB   sing N N 118 
ASP   CA  HA   sing N N 119 
ASP   C   O    doub N N 120 
ASP   C   OXT  sing N N 121 
ASP   CB  CG   sing N N 122 
ASP   CB  HB2  sing N N 123 
ASP   CB  HB3  sing N N 124 
ASP   CG  OD1  doub N N 125 
ASP   CG  OD2  sing N N 126 
ASP   OD2 HD2  sing N N 127 
ASP   OXT HXT  sing N N 128 
CYS   N   CA   sing N N 129 
CYS   N   H    sing N N 130 
CYS   N   H2   sing N N 131 
CYS   CA  C    sing N N 132 
CYS   CA  CB   sing N N 133 
CYS   CA  HA   sing N N 134 
CYS   C   O    doub N N 135 
CYS   C   OXT  sing N N 136 
CYS   CB  SG   sing N N 137 
CYS   CB  HB2  sing N N 138 
CYS   CB  HB3  sing N N 139 
CYS   SG  HG   sing N N 140 
CYS   OXT HXT  sing N N 141 
GLN   N   CA   sing N N 142 
GLN   N   H    sing N N 143 
GLN   N   H2   sing N N 144 
GLN   CA  C    sing N N 145 
GLN   CA  CB   sing N N 146 
GLN   CA  HA   sing N N 147 
GLN   C   O    doub N N 148 
GLN   C   OXT  sing N N 149 
GLN   CB  CG   sing N N 150 
GLN   CB  HB2  sing N N 151 
GLN   CB  HB3  sing N N 152 
GLN   CG  CD   sing N N 153 
GLN   CG  HG2  sing N N 154 
GLN   CG  HG3  sing N N 155 
GLN   CD  OE1  doub N N 156 
GLN   CD  NE2  sing N N 157 
GLN   NE2 HE21 sing N N 158 
GLN   NE2 HE22 sing N N 159 
GLN   OXT HXT  sing N N 160 
GLU   N   CA   sing N N 161 
GLU   N   H    sing N N 162 
GLU   N   H2   sing N N 163 
GLU   CA  C    sing N N 164 
GLU   CA  CB   sing N N 165 
GLU   CA  HA   sing N N 166 
GLU   C   O    doub N N 167 
GLU   C   OXT  sing N N 168 
GLU   CB  CG   sing N N 169 
GLU   CB  HB2  sing N N 170 
GLU   CB  HB3  sing N N 171 
GLU   CG  CD   sing N N 172 
GLU   CG  HG2  sing N N 173 
GLU   CG  HG3  sing N N 174 
GLU   CD  OE1  doub N N 175 
GLU   CD  OE2  sing N N 176 
GLU   OE2 HE2  sing N N 177 
GLU   OXT HXT  sing N N 178 
GLY   N   CA   sing N N 179 
GLY   N   H    sing N N 180 
GLY   N   H2   sing N N 181 
GLY   CA  C    sing N N 182 
GLY   CA  HA2  sing N N 183 
GLY   CA  HA3  sing N N 184 
GLY   C   O    doub N N 185 
GLY   C   OXT  sing N N 186 
GLY   OXT HXT  sing N N 187 
HIS   N   CA   sing N N 188 
HIS   N   H    sing N N 189 
HIS   N   H2   sing N N 190 
HIS   CA  C    sing N N 191 
HIS   CA  CB   sing N N 192 
HIS   CA  HA   sing N N 193 
HIS   C   O    doub N N 194 
HIS   C   OXT  sing N N 195 
HIS   CB  CG   sing N N 196 
HIS   CB  HB2  sing N N 197 
HIS   CB  HB3  sing N N 198 
HIS   CG  ND1  sing Y N 199 
HIS   CG  CD2  doub Y N 200 
HIS   ND1 CE1  doub Y N 201 
HIS   ND1 HD1  sing N N 202 
HIS   CD2 NE2  sing Y N 203 
HIS   CD2 HD2  sing N N 204 
HIS   CE1 NE2  sing Y N 205 
HIS   CE1 HE1  sing N N 206 
HIS   NE2 HE2  sing N N 207 
HIS   OXT HXT  sing N N 208 
ILE   N   CA   sing N N 209 
ILE   N   H    sing N N 210 
ILE   N   H2   sing N N 211 
ILE   CA  C    sing N N 212 
ILE   CA  CB   sing N N 213 
ILE   CA  HA   sing N N 214 
ILE   C   O    doub N N 215 
ILE   C   OXT  sing N N 216 
ILE   CB  CG1  sing N N 217 
ILE   CB  CG2  sing N N 218 
ILE   CB  HB   sing N N 219 
ILE   CG1 CD1  sing N N 220 
ILE   CG1 HG12 sing N N 221 
ILE   CG1 HG13 sing N N 222 
ILE   CG2 HG21 sing N N 223 
ILE   CG2 HG22 sing N N 224 
ILE   CG2 HG23 sing N N 225 
ILE   CD1 HD11 sing N N 226 
ILE   CD1 HD12 sing N N 227 
ILE   CD1 HD13 sing N N 228 
ILE   OXT HXT  sing N N 229 
LEU   N   CA   sing N N 230 
LEU   N   H    sing N N 231 
LEU   N   H2   sing N N 232 
LEU   CA  C    sing N N 233 
LEU   CA  CB   sing N N 234 
LEU   CA  HA   sing N N 235 
LEU   C   O    doub N N 236 
LEU   C   OXT  sing N N 237 
LEU   CB  CG   sing N N 238 
LEU   CB  HB2  sing N N 239 
LEU   CB  HB3  sing N N 240 
LEU   CG  CD1  sing N N 241 
LEU   CG  CD2  sing N N 242 
LEU   CG  HG   sing N N 243 
LEU   CD1 HD11 sing N N 244 
LEU   CD1 HD12 sing N N 245 
LEU   CD1 HD13 sing N N 246 
LEU   CD2 HD21 sing N N 247 
LEU   CD2 HD22 sing N N 248 
LEU   CD2 HD23 sing N N 249 
LEU   OXT HXT  sing N N 250 
LYS   N   CA   sing N N 251 
LYS   N   H    sing N N 252 
LYS   N   H2   sing N N 253 
LYS   CA  C    sing N N 254 
LYS   CA  CB   sing N N 255 
LYS   CA  HA   sing N N 256 
LYS   C   O    doub N N 257 
LYS   C   OXT  sing N N 258 
LYS   CB  CG   sing N N 259 
LYS   CB  HB2  sing N N 260 
LYS   CB  HB3  sing N N 261 
LYS   CG  CD   sing N N 262 
LYS   CG  HG2  sing N N 263 
LYS   CG  HG3  sing N N 264 
LYS   CD  CE   sing N N 265 
LYS   CD  HD2  sing N N 266 
LYS   CD  HD3  sing N N 267 
LYS   CE  NZ   sing N N 268 
LYS   CE  HE2  sing N N 269 
LYS   CE  HE3  sing N N 270 
LYS   NZ  HZ1  sing N N 271 
LYS   NZ  HZ2  sing N N 272 
LYS   NZ  HZ3  sing N N 273 
LYS   OXT HXT  sing N N 274 
MET   N   CA   sing N N 275 
MET   N   H    sing N N 276 
MET   N   H2   sing N N 277 
MET   CA  C    sing N N 278 
MET   CA  CB   sing N N 279 
MET   CA  HA   sing N N 280 
MET   C   O    doub N N 281 
MET   C   OXT  sing N N 282 
MET   CB  CG   sing N N 283 
MET   CB  HB2  sing N N 284 
MET   CB  HB3  sing N N 285 
MET   CG  SD   sing N N 286 
MET   CG  HG2  sing N N 287 
MET   CG  HG3  sing N N 288 
MET   SD  CE   sing N N 289 
MET   CE  HE1  sing N N 290 
MET   CE  HE2  sing N N 291 
MET   CE  HE3  sing N N 292 
MET   OXT HXT  sing N N 293 
PHE   N   CA   sing N N 294 
PHE   N   H    sing N N 295 
PHE   N   H2   sing N N 296 
PHE   CA  C    sing N N 297 
PHE   CA  CB   sing N N 298 
PHE   CA  HA   sing N N 299 
PHE   C   O    doub N N 300 
PHE   C   OXT  sing N N 301 
PHE   CB  CG   sing N N 302 
PHE   CB  HB2  sing N N 303 
PHE   CB  HB3  sing N N 304 
PHE   CG  CD1  doub Y N 305 
PHE   CG  CD2  sing Y N 306 
PHE   CD1 CE1  sing Y N 307 
PHE   CD1 HD1  sing N N 308 
PHE   CD2 CE2  doub Y N 309 
PHE   CD2 HD2  sing N N 310 
PHE   CE1 CZ   doub Y N 311 
PHE   CE1 HE1  sing N N 312 
PHE   CE2 CZ   sing Y N 313 
PHE   CE2 HE2  sing N N 314 
PHE   CZ  HZ   sing N N 315 
PHE   OXT HXT  sing N N 316 
PRO   N   CA   sing N N 317 
PRO   N   CD   sing N N 318 
PRO   N   H    sing N N 319 
PRO   CA  C    sing N N 320 
PRO   CA  CB   sing N N 321 
PRO   CA  HA   sing N N 322 
PRO   C   O    doub N N 323 
PRO   C   OXT  sing N N 324 
PRO   CB  CG   sing N N 325 
PRO   CB  HB2  sing N N 326 
PRO   CB  HB3  sing N N 327 
PRO   CG  CD   sing N N 328 
PRO   CG  HG2  sing N N 329 
PRO   CG  HG3  sing N N 330 
PRO   CD  HD2  sing N N 331 
PRO   CD  HD3  sing N N 332 
PRO   OXT HXT  sing N N 333 
SER   N   CA   sing N N 334 
SER   N   H    sing N N 335 
SER   N   H2   sing N N 336 
SER   CA  C    sing N N 337 
SER   CA  CB   sing N N 338 
SER   CA  HA   sing N N 339 
SER   C   O    doub N N 340 
SER   C   OXT  sing N N 341 
SER   CB  OG   sing N N 342 
SER   CB  HB2  sing N N 343 
SER   CB  HB3  sing N N 344 
SER   OG  HG   sing N N 345 
SER   OXT HXT  sing N N 346 
THR   N   CA   sing N N 347 
THR   N   H    sing N N 348 
THR   N   H2   sing N N 349 
THR   CA  C    sing N N 350 
THR   CA  CB   sing N N 351 
THR   CA  HA   sing N N 352 
THR   C   O    doub N N 353 
THR   C   OXT  sing N N 354 
THR   CB  OG1  sing N N 355 
THR   CB  CG2  sing N N 356 
THR   CB  HB   sing N N 357 
THR   OG1 HG1  sing N N 358 
THR   CG2 HG21 sing N N 359 
THR   CG2 HG22 sing N N 360 
THR   CG2 HG23 sing N N 361 
THR   OXT HXT  sing N N 362 
TRP   N   CA   sing N N 363 
TRP   N   H    sing N N 364 
TRP   N   H2   sing N N 365 
TRP   CA  C    sing N N 366 
TRP   CA  CB   sing N N 367 
TRP   CA  HA   sing N N 368 
TRP   C   O    doub N N 369 
TRP   C   OXT  sing N N 370 
TRP   CB  CG   sing N N 371 
TRP   CB  HB2  sing N N 372 
TRP   CB  HB3  sing N N 373 
TRP   CG  CD1  doub Y N 374 
TRP   CG  CD2  sing Y N 375 
TRP   CD1 NE1  sing Y N 376 
TRP   CD1 HD1  sing N N 377 
TRP   CD2 CE2  doub Y N 378 
TRP   CD2 CE3  sing Y N 379 
TRP   NE1 CE2  sing Y N 380 
TRP   NE1 HE1  sing N N 381 
TRP   CE2 CZ2  sing Y N 382 
TRP   CE3 CZ3  doub Y N 383 
TRP   CE3 HE3  sing N N 384 
TRP   CZ2 CH2  doub Y N 385 
TRP   CZ2 HZ2  sing N N 386 
TRP   CZ3 CH2  sing Y N 387 
TRP   CZ3 HZ3  sing N N 388 
TRP   CH2 HH2  sing N N 389 
TRP   OXT HXT  sing N N 390 
TYR   N   CA   sing N N 391 
TYR   N   H    sing N N 392 
TYR   N   H2   sing N N 393 
TYR   CA  C    sing N N 394 
TYR   CA  CB   sing N N 395 
TYR   CA  HA   sing N N 396 
TYR   C   O    doub N N 397 
TYR   C   OXT  sing N N 398 
TYR   CB  CG   sing N N 399 
TYR   CB  HB2  sing N N 400 
TYR   CB  HB3  sing N N 401 
TYR   CG  CD1  doub Y N 402 
TYR   CG  CD2  sing Y N 403 
TYR   CD1 CE1  sing Y N 404 
TYR   CD1 HD1  sing N N 405 
TYR   CD2 CE2  doub Y N 406 
TYR   CD2 HD2  sing N N 407 
TYR   CE1 CZ   doub Y N 408 
TYR   CE1 HE1  sing N N 409 
TYR   CE2 CZ   sing Y N 410 
TYR   CE2 HE2  sing N N 411 
TYR   CZ  OH   sing N N 412 
TYR   OH  HH   sing N N 413 
TYR   OXT HXT  sing N N 414 
VAL   N   CA   sing N N 415 
VAL   N   H    sing N N 416 
VAL   N   H2   sing N N 417 
VAL   CA  C    sing N N 418 
VAL   CA  CB   sing N N 419 
VAL   CA  HA   sing N N 420 
VAL   C   O    doub N N 421 
VAL   C   OXT  sing N N 422 
VAL   CB  CG1  sing N N 423 
VAL   CB  CG2  sing N N 424 
VAL   CB  HB   sing N N 425 
VAL   CG1 HG11 sing N N 426 
VAL   CG1 HG12 sing N N 427 
VAL   CG1 HG13 sing N N 428 
VAL   CG2 HG21 sing N N 429 
VAL   CG2 HG22 sing N N 430 
VAL   CG2 HG23 sing N N 431 
VAL   OXT HXT  sing N N 432 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-18 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9BFK 
_em_admin.last_update        2025-01-15 
_em_admin.map_release_date   2024-11-06 
_em_admin.title              'Cryo-EM structure of human CHT1 in the ML352 bound state' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          9606 
_em_entity_assembly_recombinant.organism             'Homo sapiens' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         60 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'FEI FALCON IV (4k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ? ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ? ? 
MASKING                         ? 3  ? ? ? ? ? 
'CTF CORRECTION'                ? 4  1 ? ? ? ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ? ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ? ? 
'MODEL FITTING'                 ? 7  ? ? ? ? ? 
'MODEL REFINEMENT'              ? 8  ? ? ? ? ? 
OTHER                           ? 9  ? ? ? ? ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ? ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ? ? 
CLASSIFICATION                  ? 12 1 ? ? ? ? 
RECONSTRUCTION                  ? 13 1 ? ? ? ? 
'VOLUME SELECTION'              ? 14 1 1 1 ? ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ? ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ? ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ? ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ? ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ? ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R35GM140892 1 
'Welch Foundation'                                                                         'United States' I-1578      2 
'Howard Hughes Medical Institute (HHMI)'                                                   'United States' ?           3 
# 
_atom_sites.entry_id                    9BFK 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . ALA   A 1 2   ? 79.486  64.149  72.299  1.00 75.44  ? 2   ALA   A N   1 
ATOM   2    C CA  . ALA   A 1 2   ? 80.840  63.640  72.479  1.00 75.44  ? 2   ALA   A CA  1 
ATOM   3    C C   . ALA   A 1 2   ? 81.369  63.977  73.869  1.00 75.44  ? 2   ALA   A C   1 
ATOM   4    O O   . ALA   A 1 2   ? 82.185  64.884  74.026  1.00 75.44  ? 2   ALA   A O   1 
ATOM   5    C CB  . ALA   A 1 2   ? 81.764  64.199  71.408  1.00 75.44  ? 2   ALA   A CB  1 
ATOM   6    N N   . PHE   A 1 3   ? 80.894  63.239  74.870  1.00 77.57  ? 3   PHE   A N   1 
ATOM   7    C CA  . PHE   A 1 3   ? 81.315  63.462  76.246  1.00 77.57  ? 3   PHE   A CA  1 
ATOM   8    C C   . PHE   A 1 3   ? 82.792  63.122  76.409  1.00 77.57  ? 3   PHE   A C   1 
ATOM   9    O O   . PHE   A 1 3   ? 83.253  62.073  75.948  1.00 77.57  ? 3   PHE   A O   1 
ATOM   10   C CB  . PHE   A 1 3   ? 80.469  62.613  77.193  1.00 77.57  ? 3   PHE   A CB  1 
ATOM   11   C CG  . PHE   A 1 3   ? 80.560  63.028  78.632  1.00 77.57  ? 3   PHE   A CG  1 
ATOM   12   C CD1 . PHE   A 1 3   ? 79.745  64.031  79.129  1.00 77.57  ? 3   PHE   A CD1 1 
ATOM   13   C CD2 . PHE   A 1 3   ? 81.455  62.412  79.491  1.00 77.57  ? 3   PHE   A CD2 1 
ATOM   14   C CE1 . PHE   A 1 3   ? 79.819  64.413  80.454  1.00 77.57  ? 3   PHE   A CE1 1 
ATOM   15   C CE2 . PHE   A 1 3   ? 81.537  62.792  80.817  1.00 77.57  ? 3   PHE   A CE2 1 
ATOM   16   C CZ  . PHE   A 1 3   ? 80.718  63.793  81.299  1.00 77.57  ? 3   PHE   A CZ  1 
ATOM   17   N N   . HIS   A 1 4   ? 83.535  64.011  77.065  1.00 76.04  ? 4   HIS   A N   1 
ATOM   18   C CA  . HIS   A 1 4   ? 84.967  63.840  77.285  1.00 76.04  ? 4   HIS   A CA  1 
ATOM   19   C C   . HIS   A 1 4   ? 85.198  63.473  78.746  1.00 76.04  ? 4   HIS   A C   1 
ATOM   20   O O   . HIS   A 1 4   ? 85.084  64.327  79.632  1.00 76.04  ? 4   HIS   A O   1 
ATOM   21   C CB  . HIS   A 1 4   ? 85.736  65.104  76.909  1.00 76.04  ? 4   HIS   A CB  1 
ATOM   22   C CG  . HIS   A 1 4   ? 85.779  65.371  75.437  1.00 76.04  ? 4   HIS   A CG  1 
ATOM   23   N ND1 . HIS   A 1 4   ? 86.030  66.621  74.914  1.00 76.04  ? 4   HIS   A ND1 1 
ATOM   24   C CD2 . HIS   A 1 4   ? 85.604  64.548  74.376  1.00 76.04  ? 4   HIS   A CD2 1 
ATOM   25   C CE1 . HIS   A 1 4   ? 86.008  66.557  73.595  1.00 76.04  ? 4   HIS   A CE1 1 
ATOM   26   N NE2 . HIS   A 1 4   ? 85.751  65.310  73.243  1.00 76.04  ? 4   HIS   A NE2 1 
ATOM   27   N N   . VAL   A 1 5   ? 85.522  62.202  78.991  1.00 78.31  ? 5   VAL   A N   1 
ATOM   28   C CA  . VAL   A 1 5   ? 85.821  61.754  80.347  1.00 78.31  ? 5   VAL   A CA  1 
ATOM   29   C C   . VAL   A 1 5   ? 87.158  62.320  80.814  1.00 78.31  ? 5   VAL   A C   1 
ATOM   30   O O   . VAL   A 1 5   ? 87.307  62.719  81.977  1.00 78.31  ? 5   VAL   A O   1 
ATOM   31   C CB  . VAL   A 1 5   ? 85.796  60.215  80.409  1.00 78.31  ? 5   VAL   A CB  1 
ATOM   32   C CG1 . VAL   A 1 5   ? 86.192  59.717  81.793  1.00 78.31  ? 5   VAL   A CG1 1 
ATOM   33   C CG2 . VAL   A 1 5   ? 84.421  59.692  80.022  1.00 78.31  ? 5   VAL   A CG2 1 
ATOM   34   N N   . GLU   A 1 6   ? 88.144  62.375  79.912  1.00 80.48  ? 6   GLU   A N   1 
ATOM   35   C CA  . GLU   A 1 6   ? 89.491  62.796  80.285  1.00 80.48  ? 6   GLU   A CA  1 
ATOM   36   C C   . GLU   A 1 6   ? 89.534  64.243  80.764  1.00 80.48  ? 6   GLU   A C   1 
ATOM   37   O O   . GLU   A 1 6   ? 90.311  64.569  81.667  1.00 80.48  ? 6   GLU   A O   1 
ATOM   38   C CB  . GLU   A 1 6   ? 90.450  62.583  79.110  1.00 80.48  ? 6   GLU   A CB  1 
ATOM   39   C CG  . GLU   A 1 6   ? 90.091  63.347  77.844  1.00 80.48  ? 6   GLU   A CG  1 
ATOM   40   C CD  . GLU   A 1 6   ? 91.016  63.028  76.687  1.00 80.48  ? 6   GLU   A CD  1 
ATOM   41   O OE1 . GLU   A 1 6   ? 92.128  62.518  76.936  1.00 80.48  ? 6   GLU   A OE1 1 
ATOM   42   O OE2 . GLU   A 1 6   ? 90.629  63.287  75.528  1.00 80.48  ? 6   GLU   A OE2 1 
ATOM   43   N N   . GLY   A 1 7   ? 88.706  65.120  80.193  1.00 72.00  ? 7   GLY   A N   1 
ATOM   44   C CA  . GLY   A 1 7   ? 88.654  66.490  80.678  1.00 72.00  ? 7   GLY   A CA  1 
ATOM   45   C C   . GLY   A 1 7   ? 88.097  66.586  82.086  1.00 72.00  ? 7   GLY   A C   1 
ATOM   46   O O   . GLY   A 1 7   ? 88.579  67.377  82.905  1.00 72.00  ? 7   GLY   A O   1 
ATOM   47   N N   . LEU   A 1 8   ? 87.073  65.783  82.385  1.00 69.57  ? 8   LEU   A N   1 
ATOM   48   C CA  . LEU   A 1 8   ? 86.530  65.745  83.738  1.00 69.57  ? 8   LEU   A CA  1 
ATOM   49   C C   . LEU   A 1 8   ? 87.558  65.202  84.723  1.00 69.57  ? 8   LEU   A C   1 
ATOM   50   O O   . LEU   A 1 8   ? 87.693  65.718  85.840  1.00 69.57  ? 8   LEU   A O   1 
ATOM   51   C CB  . LEU   A 1 8   ? 85.253  64.907  83.766  1.00 69.57  ? 8   LEU   A CB  1 
ATOM   52   C CG  . LEU   A 1 8   ? 84.482  64.887  85.085  1.00 69.57  ? 8   LEU   A CG  1 
ATOM   53   C CD1 . LEU   A 1 8   ? 84.059  66.294  85.472  1.00 69.57  ? 8   LEU   A CD1 1 
ATOM   54   C CD2 . LEU   A 1 8   ? 83.271  63.977  84.978  1.00 69.57  ? 8   LEU   A CD2 1 
ATOM   55   N N   . ILE   A 1 9   ? 88.304  64.171  84.318  1.00 68.42  ? 9   ILE   A N   1 
ATOM   56   C CA  . ILE   A 1 9   ? 89.381  63.656  85.160  1.00 68.42  ? 9   ILE   A CA  1 
ATOM   57   C C   . ILE   A 1 9   ? 90.434  64.731  85.400  1.00 68.42  ? 9   ILE   A C   1 
ATOM   58   O O   . ILE   A 1 9   ? 90.923  64.895  86.522  1.00 68.42  ? 9   ILE   A O   1 
ATOM   59   C CB  . ILE   A 1 9   ? 89.995  62.387  84.538  1.00 68.42  ? 9   ILE   A CB  1 
ATOM   60   C CG1 . ILE   A 1 9   ? 88.931  61.301  84.373  1.00 68.42  ? 9   ILE   A CG1 1 
ATOM   61   C CG2 . ILE   A 1 9   ? 91.144  61.868  85.389  1.00 68.42  ? 9   ILE   A CG2 1 
ATOM   62   C CD1 . ILE   A 1 9   ? 88.304  60.860  85.677  1.00 68.42  ? 9   ILE   A CD1 1 
ATOM   63   N N   . ALA   A 1 10  ? 90.785  65.488  84.357  1.00 65.71  ? 10  ALA   A N   1 
ATOM   64   C CA  . ALA   A 1 10  ? 91.793  66.537  84.493  1.00 65.71  ? 10  ALA   A CA  1 
ATOM   65   C C   . ALA   A 1 10  ? 91.345  67.622  85.464  1.00 65.71  ? 10  ALA   A C   1 
ATOM   66   O O   . ALA   A 1 10  ? 92.112  68.038  86.343  1.00 65.71  ? 10  ALA   A O   1 
ATOM   67   C CB  . ALA   A 1 10  ? 92.102  67.147  83.127  1.00 65.71  ? 10  ALA   A CB  1 
ATOM   68   N N   . ILE   A 1 11  ? 90.103  68.094  85.324  1.00 62.74  ? 11  ILE   A N   1 
ATOM   69   C CA  . ILE   A 1 11  ? 89.640  69.173  86.193  1.00 62.74  ? 11  ILE   A CA  1 
ATOM   70   C C   . ILE   A 1 11  ? 89.494  68.680  87.631  1.00 62.74  ? 11  ILE   A C   1 
ATOM   71   O O   . ILE   A 1 11  ? 89.825  69.405  88.577  1.00 62.74  ? 11  ILE   A O   1 
ATOM   72   C CB  . ILE   A 1 11  ? 88.344  69.813  85.649  1.00 62.74  ? 11  ILE   A CB  1 
ATOM   73   C CG1 . ILE   A 1 11  ? 87.953  71.030  86.488  1.00 62.74  ? 11  ILE   A CG1 1 
ATOM   74   C CG2 . ILE   A 1 11  ? 87.191  68.839  85.593  1.00 62.74  ? 11  ILE   A CG2 1 
ATOM   75   C CD1 . ILE   A 1 11  ? 86.801  71.816  85.910  1.00 62.74  ? 11  ILE   A CD1 1 
ATOM   76   N N   . ILE   A 1 12  ? 89.053  67.430  87.824  1.00 64.92  ? 12  ILE   A N   1 
ATOM   77   C CA  . ILE   A 1 12  ? 88.954  66.878  89.173  1.00 64.92  ? 12  ILE   A CA  1 
ATOM   78   C C   . ILE   A 1 12  ? 90.336  66.741  89.805  1.00 64.92  ? 12  ILE   A C   1 
ATOM   79   O O   . ILE   A 1 12  ? 90.545  67.117  90.965  1.00 64.92  ? 12  ILE   A O   1 
ATOM   80   C CB  . ILE   A 1 12  ? 88.205  65.532  89.147  1.00 64.92  ? 12  ILE   A CB  1 
ATOM   81   C CG1 . ILE   A 1 12  ? 86.712  65.757  88.903  1.00 64.92  ? 12  ILE   A CG1 1 
ATOM   82   C CG2 . ILE   A 1 12  ? 88.420  64.760  90.439  1.00 64.92  ? 12  ILE   A CG2 1 
ATOM   83   C CD1 . ILE   A 1 12  ? 85.962  64.498  88.536  1.00 64.92  ? 12  ILE   A CD1 1 
ATOM   84   N N   . VAL   A 1 13  ? 91.302  66.214  89.046  1.00 63.56  ? 13  VAL   A N   1 
ATOM   85   C CA  . VAL   A 1 13  ? 92.650  66.012  89.571  1.00 63.56  ? 13  VAL   A CA  1 
ATOM   86   C C   . VAL   A 1 13  ? 93.288  67.344  89.939  1.00 63.56  ? 13  VAL   A C   1 
ATOM   87   O O   . VAL   A 1 13  ? 93.900  67.477  91.003  1.00 63.56  ? 13  VAL   A O   1 
ATOM   88   C CB  . VAL   A 1 13  ? 93.505  65.222  88.560  1.00 63.56  ? 13  VAL   A CB  1 
ATOM   89   C CG1 . VAL   A 1 13  ? 94.985  65.366  88.866  1.00 63.56  ? 13  VAL   A CG1 1 
ATOM   90   C CG2 . VAL   A 1 13  ? 93.120  63.754  88.586  1.00 63.56  ? 13  VAL   A CG2 1 
ATOM   91   N N   . PHE   A 1 14  ? 93.130  68.360  89.088  1.00 62.92  ? 14  PHE   A N   1 
ATOM   92   C CA  . PHE   A 1 14  ? 93.736  69.654  89.389  1.00 62.92  ? 14  PHE   A CA  1 
ATOM   93   C C   . PHE   A 1 14  ? 93.032  70.354  90.549  1.00 62.92  ? 14  PHE   A C   1 
ATOM   94   O O   . PHE   A 1 14  ? 93.688  71.016  91.365  1.00 62.92  ? 14  PHE   A O   1 
ATOM   95   C CB  . PHE   A 1 14  ? 93.745  70.532  88.142  1.00 62.92  ? 14  PHE   A CB  1 
ATOM   96   C CG  . PHE   A 1 14  ? 94.976  70.370  87.303  1.00 62.92  ? 14  PHE   A CG  1 
ATOM   97   C CD1 . PHE   A 1 14  ? 96.186  70.897  87.722  1.00 62.92  ? 14  PHE   A CD1 1 
ATOM   98   C CD2 . PHE   A 1 14  ? 94.928  69.685  86.102  1.00 62.92  ? 14  PHE   A CD2 1 
ATOM   99   C CE1 . PHE   A 1 14  ? 97.323  70.747  86.956  1.00 62.92  ? 14  PHE   A CE1 1 
ATOM   100  C CE2 . PHE   A 1 14  ? 96.062  69.533  85.330  1.00 62.92  ? 14  PHE   A CE2 1 
ATOM   101  C CZ  . PHE   A 1 14  ? 97.261  70.064  85.758  1.00 62.92  ? 14  PHE   A CZ  1 
ATOM   102  N N   . TYR   A 1 15  ? 91.705  70.215  90.653  1.00 65.03  ? 15  TYR   A N   1 
ATOM   103  C CA  . TYR   A 1 15  ? 90.985  70.803  91.779  1.00 65.03  ? 15  TYR   A CA  1 
ATOM   104  C C   . TYR   A 1 15  ? 91.426  70.176  93.097  1.00 65.03  ? 15  TYR   A C   1 
ATOM   105  O O   . TYR   A 1 15  ? 91.697  70.884  94.076  1.00 65.03  ? 15  TYR   A O   1 
ATOM   106  C CB  . TYR   A 1 15  ? 89.478  70.635  91.575  1.00 65.03  ? 15  TYR   A CB  1 
ATOM   107  C CG  . TYR   A 1 15  ? 88.617  71.500  92.472  1.00 65.03  ? 15  TYR   A CG  1 
ATOM   108  C CD1 . TYR   A 1 15  ? 88.316  71.110  93.772  1.00 65.03  ? 15  TYR   A CD1 1 
ATOM   109  C CD2 . TYR   A 1 15  ? 88.099  72.703  92.015  1.00 65.03  ? 15  TYR   A CD2 1 
ATOM   110  C CE1 . TYR   A 1 15  ? 87.529  71.898  94.589  1.00 65.03  ? 15  TYR   A CE1 1 
ATOM   111  C CE2 . TYR   A 1 15  ? 87.310  73.495  92.825  1.00 65.03  ? 15  TYR   A CE2 1 
ATOM   112  C CZ  . TYR   A 1 15  ? 87.029  73.089  94.110  1.00 65.03  ? 15  TYR   A CZ  1 
ATOM   113  O OH  . TYR   A 1 15  ? 86.245  73.877  94.919  1.00 65.03  ? 15  TYR   A OH  1 
ATOM   114  N N   . LEU   A 1 16  ? 91.525  68.845  93.135  1.00 69.14  ? 16  LEU   A N   1 
ATOM   115  C CA  . LEU   A 1 16  ? 92.006  68.190  94.348  1.00 69.14  ? 16  LEU   A CA  1 
ATOM   116  C C   . LEU   A 1 16  ? 93.476  68.489  94.613  1.00 69.14  ? 16  LEU   A C   1 
ATOM   117  O O   . LEU   A 1 16  ? 93.883  68.565  95.774  1.00 69.14  ? 16  LEU   A O   1 
ATOM   118  C CB  . LEU   A 1 16  ? 91.765  66.679  94.287  1.00 69.14  ? 16  LEU   A CB  1 
ATOM   119  C CG  . LEU   A 1 16  ? 90.390  66.116  94.680  1.00 69.14  ? 16  LEU   A CG  1 
ATOM   120  C CD1 . LEU   A 1 16  ? 90.122  66.400  96.151  1.00 69.14  ? 16  LEU   A CD1 1 
ATOM   121  C CD2 . LEU   A 1 16  ? 89.231  66.619  93.831  1.00 69.14  ? 16  LEU   A CD2 1 
ATOM   122  N N   . LEU   A 1 17  ? 94.287  68.666  93.569  1.00 69.81  ? 17  LEU   A N   1 
ATOM   123  C CA  . LEU   A 1 17  ? 95.680  69.040  93.782  1.00 69.81  ? 17  LEU   A CA  1 
ATOM   124  C C   . LEU   A 1 17  ? 95.783  70.408  94.442  1.00 69.81  ? 17  LEU   A C   1 
ATOM   125  O O   . LEU   A 1 17  ? 96.555  70.589  95.390  1.00 69.81  ? 17  LEU   A O   1 
ATOM   126  C CB  . LEU   A 1 17  ? 96.437  69.022  92.455  1.00 69.81  ? 17  LEU   A CB  1 
ATOM   127  C CG  . LEU   A 1 17  ? 97.920  69.389  92.513  1.00 69.81  ? 17  LEU   A CG  1 
ATOM   128  C CD1 . LEU   A 1 17  ? 98.673  68.420  93.408  1.00 69.81  ? 17  LEU   A CD1 1 
ATOM   129  C CD2 . LEU   A 1 17  ? 98.519  69.408  91.118  1.00 69.81  ? 17  LEU   A CD2 1 
ATOM   130  N N   . ILE   A 1 18  ? 94.984  71.372  93.976  1.00 67.38  ? 18  ILE   A N   1 
ATOM   131  C CA  . ILE   A 1 18  ? 94.942  72.691  94.607  1.00 67.38  ? 18  ILE   A CA  1 
ATOM   132  C C   . ILE   A 1 18  ? 94.460  72.575  96.050  1.00 67.38  ? 18  ILE   A C   1 
ATOM   133  O O   . ILE   A 1 18  ? 95.002  73.220  96.959  1.00 67.38  ? 18  ILE   A O   1 
ATOM   134  C CB  . ILE   A 1 18  ? 94.054  73.642  93.781  1.00 67.38  ? 18  ILE   A CB  1 
ATOM   135  C CG1 . ILE   A 1 18  ? 94.755  74.030  92.479  1.00 67.38  ? 18  ILE   A CG1 1 
ATOM   136  C CG2 . ILE   A 1 18  ? 93.702  74.892  94.571  1.00 67.38  ? 18  ILE   A CG2 1 
ATOM   137  C CD1 . ILE   A 1 18  ? 93.926  74.923  91.588  1.00 67.38  ? 18  ILE   A CD1 1 
ATOM   138  N N   . LEU   A 1 19  ? 93.447  71.734  96.283  1.00 73.26  ? 19  LEU   A N   1 
ATOM   139  C CA  . LEU   A 1 19  ? 92.893  71.575  97.625  1.00 73.26  ? 19  LEU   A CA  1 
ATOM   140  C C   . LEU   A 1 19  ? 93.915  70.992  98.600  1.00 73.26  ? 19  LEU   A C   1 
ATOM   141  O O   . LEU   A 1 19  ? 94.070  71.492  99.721  1.00 73.26  ? 19  LEU   A O   1 
ATOM   142  C CB  . LEU   A 1 19  ? 91.638  70.705  97.551  1.00 73.26  ? 19  LEU   A CB  1 
ATOM   143  C CG  . LEU   A 1 19  ? 90.748  70.539  98.780  1.00 73.26  ? 19  LEU   A CG  1 
ATOM   144  C CD1 . LEU   A 1 19  ? 89.291  70.630  98.370  1.00 73.26  ? 19  LEU   A CD1 1 
ATOM   145  C CD2 . LEU   A 1 19  ? 91.015  69.199  99.433  1.00 73.26  ? 19  LEU   A CD2 1 
ATOM   146  N N   . LEU   A 1 20  ? 94.642  69.948  98.189  1.00 76.35  ? 20  LEU   A N   1 
ATOM   147  C CA  . LEU   A 1 20  ? 95.661  69.382  99.072  1.00 76.35  ? 20  LEU   A CA  1 
ATOM   148  C C   . LEU   A 1 20  ? 96.893  70.273  99.200  1.00 76.35  ? 20  LEU   A C   1 
ATOM   149  O O   . LEU   A 1 20  ? 97.560  70.233  100.238 1.00 76.35  ? 20  LEU   A O   1 
ATOM   150  C CB  . LEU   A 1 20  ? 96.061  67.970  98.634  1.00 76.35  ? 20  LEU   A CB  1 
ATOM   151  C CG  . LEU   A 1 20  ? 95.159  66.780  99.004  1.00 76.35  ? 20  LEU   A CG  1 
ATOM   152  C CD1 . LEU   A 1 20  ? 93.837  66.698  98.266  1.00 76.35  ? 20  LEU   A CD1 1 
ATOM   153  C CD2 . LEU   A 1 20  ? 95.940  65.483  98.825  1.00 76.35  ? 20  LEU   A CD2 1 
ATOM   154  N N   . VAL   A 1 21  ? 97.214  71.088  98.191  1.00 78.81  ? 21  VAL   A N   1 
ATOM   155  C CA  . VAL   A 1 21  ? 98.278  72.074  98.382  1.00 78.81  ? 21  VAL   A CA  1 
ATOM   156  C C   . VAL   A 1 21  ? 97.866  73.103  99.431  1.00 78.81  ? 21  VAL   A C   1 
ATOM   157  O O   . VAL   A 1 21  ? 98.672  73.493  100.287 1.00 78.81  ? 21  VAL   A O   1 
ATOM   158  C CB  . VAL   A 1 21  ? 98.665  72.733  97.044  1.00 78.81  ? 21  VAL   A CB  1 
ATOM   159  C CG1 . VAL   A 1 21  ? 99.569  73.929  97.277  1.00 78.81  ? 21  VAL   A CG1 1 
ATOM   160  C CG2 . VAL   A 1 21  ? 99.399  71.736  96.167  1.00 78.81  ? 21  VAL   A CG2 1 
ATOM   161  N N   . GLY   A 1 22  ? 96.605  73.539  99.401  1.00 83.30  ? 22  GLY   A N   1 
ATOM   162  C CA  . GLY   A 1 22  ? 96.117  74.427  100.448 1.00 83.30  ? 22  GLY   A CA  1 
ATOM   163  C C   . GLY   A 1 22  ? 96.125  73.779  101.822 1.00 83.30  ? 22  GLY   A C   1 
ATOM   164  O O   . GLY   A 1 22  ? 96.460  74.422  102.823 1.00 83.30  ? 22  GLY   A O   1 
ATOM   165  N N   . ILE   A 1 23  ? 95.761  72.494  101.886 1.00 84.43  ? 23  ILE   A N   1 
ATOM   166  C CA  . ILE   A 1 23  ? 95.801  71.764  103.154 1.00 84.43  ? 23  ILE   A CA  1 
ATOM   167  C C   . ILE   A 1 23  ? 97.230  71.667  103.677 1.00 84.43  ? 23  ILE   A C   1 
ATOM   168  O O   . ILE   A 1 23  ? 97.477  71.848  104.873 1.00 84.43  ? 23  ILE   A O   1 
ATOM   169  C CB  . ILE   A 1 23  ? 95.157  70.373  102.996 1.00 84.43  ? 23  ILE   A CB  1 
ATOM   170  C CG1 . ILE   A 1 23  ? 93.646  70.500  102.811 1.00 84.43  ? 23  ILE   A CG1 1 
ATOM   171  C CG2 . ILE   A 1 23  ? 95.462  69.484  104.193 1.00 84.43  ? 23  ILE   A CG2 1 
ATOM   172  C CD1 . ILE   A 1 23  ? 92.968  69.186  102.515 1.00 84.43  ? 23  ILE   A CD1 1 
ATOM   173  N N   . TRP   A 1 24  ? 98.190  71.386  102.794 1.00 91.17  ? 24  TRP   A N   1 
ATOM   174  C CA  . TRP   A 1 24  ? 99.591  71.321  103.204 1.00 91.17  ? 24  TRP   A CA  1 
ATOM   175  C C   . TRP   A 1 24  ? 100.101 72.681  103.670 1.00 91.17  ? 24  TRP   A C   1 
ATOM   176  O O   . TRP   A 1 24  ? 100.880 72.763  104.629 1.00 91.17  ? 24  TRP   A O   1 
ATOM   177  C CB  . TRP   A 1 24  ? 100.445 70.794  102.053 1.00 91.17  ? 24  TRP   A CB  1 
ATOM   178  C CG  . TRP   A 1 24  ? 101.900 70.703  102.376 1.00 91.17  ? 24  TRP   A CG  1 
ATOM   179  C CD1 . TRP   A 1 24  ? 102.482 69.907  103.318 1.00 91.17  ? 24  TRP   A CD1 1 
ATOM   180  C CD2 . TRP   A 1 24  ? 102.963 71.436  101.758 1.00 91.17  ? 24  TRP   A CD2 1 
ATOM   181  N NE1 . TRP   A 1 24  ? 103.843 70.098  103.324 1.00 91.17  ? 24  TRP   A NE1 1 
ATOM   182  C CE2 . TRP   A 1 24  ? 104.163 71.033  102.375 1.00 91.17  ? 24  TRP   A CE2 1 
ATOM   183  C CE3 . TRP   A 1 24  ? 103.017 72.395  100.742 1.00 91.17  ? 24  TRP   A CE3 1 
ATOM   184  C CZ2 . TRP   A 1 24  ? 105.402 71.555  102.010 1.00 91.17  ? 24  TRP   A CZ2 1 
ATOM   185  C CZ3 . TRP   A 1 24  ? 104.247 72.912  100.381 1.00 91.17  ? 24  TRP   A CZ3 1 
ATOM   186  C CH2 . TRP   A 1 24  ? 105.423 72.491  101.013 1.00 91.17  ? 24  TRP   A CH2 1 
ATOM   187  N N   . ALA   A 1 25  ? 99.685  73.755  102.994 1.00 91.42  ? 25  ALA   A N   1 
ATOM   188  C CA  . ALA   A 1 25  ? 100.078 75.097  103.411 1.00 91.42  ? 25  ALA   A CA  1 
ATOM   189  C C   . ALA   A 1 25  ? 99.524  75.431  104.790 1.00 91.42  ? 25  ALA   A C   1 
ATOM   190  O O   . ALA   A 1 25  ? 100.214 76.047  105.611 1.00 91.42  ? 25  ALA   A O   1 
ATOM   191  C CB  . ALA   A 1 25  ? 99.616  76.126  102.380 1.00 91.42  ? 25  ALA   A CB  1 
ATOM   192  N N   . ALA   A 1 26  ? 98.276  75.040  105.060 1.00 96.07  ? 26  ALA   A N   1 
ATOM   193  C CA  . ALA   A 1 26  ? 97.729  75.215  106.403 1.00 96.07  ? 26  ALA   A CA  1 
ATOM   194  C C   . ALA   A 1 26  ? 98.433  74.321  107.419 1.00 96.07  ? 26  ALA   A C   1 
ATOM   195  O O   . ALA   A 1 26  ? 98.573  74.701  108.587 1.00 96.07  ? 26  ALA   A O   1 
ATOM   196  C CB  . ALA   A 1 26  ? 96.227  74.938  106.401 1.00 96.07  ? 26  ALA   A CB  1 
ATOM   197  N N   . TRP   A 1 27  ? 98.868  73.133  106.993 1.00 100.80 ? 27  TRP   A N   1 
ATOM   198  C CA  . TRP   A 1 27  ? 99.581  72.214  107.875 1.00 100.80 ? 27  TRP   A CA  1 
ATOM   199  C C   . TRP   A 1 27  ? 100.928 72.784  108.299 1.00 100.80 ? 27  TRP   A C   1 
ATOM   200  O O   . TRP   A 1 27  ? 101.346 72.611  109.450 1.00 100.80 ? 27  TRP   A O   1 
ATOM   201  C CB  . TRP   A 1 27  ? 99.762  70.866  107.175 1.00 100.80 ? 27  TRP   A CB  1 
ATOM   202  C CG  . TRP   A 1 27  ? 100.607 69.881  107.926 1.00 100.80 ? 27  TRP   A CG  1 
ATOM   203  C CD1 . TRP   A 1 27  ? 101.912 69.567  107.679 1.00 100.80 ? 27  TRP   A CD1 1 
ATOM   204  C CD2 . TRP   A 1 27  ? 100.199 69.063  109.029 1.00 100.80 ? 27  TRP   A CD2 1 
ATOM   205  N NE1 . TRP   A 1 27  ? 102.346 68.614  108.568 1.00 100.80 ? 27  TRP   A NE1 1 
ATOM   206  C CE2 . TRP   A 1 27  ? 101.313 68.287  109.406 1.00 100.80 ? 27  TRP   A CE2 1 
ATOM   207  C CE3 . TRP   A 1 27  ? 99.003  68.915  109.738 1.00 100.80 ? 27  TRP   A CE3 1 
ATOM   208  C CZ2 . TRP   A 1 27  ? 101.266 67.377  110.460 1.00 100.80 ? 27  TRP   A CZ2 1 
ATOM   209  C CZ3 . TRP   A 1 27  ? 98.958  68.011  110.784 1.00 100.80 ? 27  TRP   A CZ3 1 
ATOM   210  C CH2 . TRP   A 1 27  ? 100.083 67.254  111.135 1.00 100.80 ? 27  TRP   A CH2 1 
ATOM   211  N N   . ARG   A 1 28  ? 101.630 73.448  107.377 1.00 103.60 ? 28  ARG   A N   1 
ATOM   212  C CA  . ARG   A 1 28  ? 102.889 74.096  107.734 1.00 103.60 ? 28  ARG   A CA  1 
ATOM   213  C C   . ARG   A 1 28  ? 102.668 75.229  108.730 1.00 103.60 ? 28  ARG   A C   1 
ATOM   214  O O   . ARG   A 1 28  ? 103.430 75.377  109.693 1.00 103.60 ? 28  ARG   A O   1 
ATOM   215  C CB  . ARG   A 1 28  ? 103.594 74.613  106.481 1.00 103.60 ? 28  ARG   A CB  1 
ATOM   216  C CG  . ARG   A 1 28  ? 104.916 75.306  106.768 1.00 103.60 ? 28  ARG   A CG  1 
ATOM   217  C CD  . ARG   A 1 28  ? 105.600 75.768  105.493 1.00 103.60 ? 28  ARG   A CD  1 
ATOM   218  N NE  . ARG   A 1 28  ? 106.140 74.651  104.727 1.00 103.60 ? 28  ARG   A NE  1 
ATOM   219  C CZ  . ARG   A 1 28  ? 107.291 74.048  104.991 1.00 103.60 ? 28  ARG   A CZ  1 
ATOM   220  N NH1 . ARG   A 1 28  ? 108.059 74.432  105.998 1.00 103.60 ? 28  ARG   A NH1 1 
ATOM   221  N NH2 . ARG   A 1 28  ? 107.684 73.035  104.223 1.00 103.60 ? 28  ARG   A NH2 1 
ATOM   222  N N   . THR   A 1 29  ? 101.631 76.034  108.520 1.00 102.30 ? 29  THR   A N   1 
ATOM   223  C CA  . THR   A 1 29  ? 101.335 77.146  109.416 1.00 102.30 ? 29  THR   A CA  1 
ATOM   224  C C   . THR   A 1 29  ? 100.730 76.650  110.726 1.00 102.30 ? 29  THR   A C   1 
ATOM   225  O O   . THR   A 1 29  ? 99.524  76.424  110.820 1.00 102.30 ? 29  THR   A O   1 
ATOM   226  C CB  . THR   A 1 29  ? 100.370 78.155  108.765 1.00 102.30 ? 29  THR   A CB  1 
ATOM   227  O OG1 . THR   A 1 29  ? 100.836 78.486  107.452 1.00 102.30 ? 29  THR   A OG1 1 
ATOM   228  C CG2 . THR   A 1 29  ? 100.284 79.424  109.600 1.00 102.30 ? 29  THR   A CG2 1 
ATOM   229  N N   . ARG   A 1 47  ? 112.655 84.707  104.836 1.00 113.48 ? 47  ARG   A N   1 
ATOM   230  C CA  . ARG   A 1 47  ? 113.363 85.803  104.184 1.00 113.48 ? 47  ARG   A CA  1 
ATOM   231  C C   . ARG   A 1 47  ? 112.468 87.031  104.059 1.00 113.48 ? 47  ARG   A C   1 
ATOM   232  O O   . ARG   A 1 47  ? 112.816 87.990  103.368 1.00 113.48 ? 47  ARG   A O   1 
ATOM   233  C CB  . ARG   A 1 47  ? 113.864 85.372  102.804 1.00 113.48 ? 47  ARG   A CB  1 
ATOM   234  C CG  . ARG   A 1 47  ? 114.937 84.294  102.841 1.00 113.48 ? 47  ARG   A CG  1 
ATOM   235  C CD  . ARG   A 1 47  ? 115.376 83.906  101.437 1.00 113.48 ? 47  ARG   A CD  1 
ATOM   236  N NE  . ARG   A 1 47  ? 116.416 82.884  101.447 1.00 113.48 ? 47  ARG   A NE  1 
ATOM   237  C CZ  . ARG   A 1 47  ? 117.706 83.126  101.643 1.00 113.48 ? 47  ARG   A CZ  1 
ATOM   238  N NH1 . ARG   A 1 47  ? 118.156 84.354  101.845 1.00 113.48 ? 47  ARG   A NH1 1 
ATOM   239  N NH2 . ARG   A 1 47  ? 118.565 82.111  101.634 1.00 113.48 ? 47  ARG   A NH2 1 
ATOM   240  N N   . ASP   A 1 48  ? 111.321 86.979  104.741 1.00 105.07 ? 48  ASP   A N   1 
ATOM   241  C CA  . ASP   A 1 48  ? 110.306 88.035  104.728 1.00 105.07 ? 48  ASP   A CA  1 
ATOM   242  C C   . ASP   A 1 48  ? 109.843 88.339  103.301 1.00 105.07 ? 48  ASP   A C   1 
ATOM   243  O O   . ASP   A 1 48  ? 109.924 89.468  102.813 1.00 105.07 ? 48  ASP   A O   1 
ATOM   244  C CB  . ASP   A 1 48  ? 110.810 89.301  105.431 1.00 105.07 ? 48  ASP   A CB  1 
ATOM   245  C CG  . ASP   A 1 48  ? 109.679 90.201  105.891 1.00 105.07 ? 48  ASP   A CG  1 
ATOM   246  O OD1 . ASP   A 1 48  ? 108.510 89.765  105.833 1.00 105.07 ? 48  ASP   A OD1 1 
ATOM   247  O OD2 . ASP   A 1 48  ? 109.957 91.344  106.311 1.00 105.07 ? 48  ASP   A OD2 1 
ATOM   248  N N   . ILE   A 1 49  ? 109.354 87.297  102.636 1.00 90.79  ? 49  ILE   A N   1 
ATOM   249  C CA  . ILE   A 1 49  ? 108.798 87.423  101.298 1.00 90.79  ? 49  ILE   A CA  1 
ATOM   250  C C   . ILE   A 1 49  ? 107.274 87.549  101.339 1.00 90.79  ? 49  ILE   A C   1 
ATOM   251  O O   . ILE   A 1 49  ? 106.608 87.323  100.330 1.00 90.79  ? 49  ILE   A O   1 
ATOM   252  C CB  . ILE   A 1 49  ? 109.235 86.261  100.394 1.00 90.79  ? 49  ILE   A CB  1 
ATOM   253  C CG1 . ILE   A 1 49  ? 108.723 84.930  100.948 1.00 90.79  ? 49  ILE   A CG1 1 
ATOM   254  C CG2 . ILE   A 1 49  ? 110.747 86.238  100.253 1.00 90.79  ? 49  ILE   A CG2 1 
ATOM   255  C CD1 . ILE   A 1 49  ? 108.907 83.766  100.002 1.00 90.79  ? 49  ILE   A CD1 1 
ATOM   256  N N   . GLY   A 1 50  ? 106.713 87.910  102.494 1.00 79.03  ? 50  GLY   A N   1 
ATOM   257  C CA  . GLY   A 1 50  ? 105.274 88.052  102.616 1.00 79.03  ? 50  GLY   A CA  1 
ATOM   258  C C   . GLY   A 1 50  ? 104.694 89.198  101.817 1.00 79.03  ? 50  GLY   A C   1 
ATOM   259  O O   . GLY   A 1 50  ? 103.495 89.188  101.525 1.00 79.03  ? 50  GLY   A O   1 
ATOM   260  N N   . LEU   A 1 51  ? 105.517 90.186  101.460 1.00 74.08  ? 51  LEU   A N   1 
ATOM   261  C CA  . LEU   A 1 51  ? 105.050 91.272  100.603 1.00 74.08  ? 51  LEU   A CA  1 
ATOM   262  C C   . LEU   A 1 51  ? 104.684 90.758  99.216  1.00 74.08  ? 51  LEU   A C   1 
ATOM   263  O O   . LEU   A 1 51  ? 103.637 91.115  98.663  1.00 74.08  ? 51  LEU   A O   1 
ATOM   264  C CB  . LEU   A 1 51  ? 106.123 92.357  100.514 1.00 74.08  ? 51  LEU   A CB  1 
ATOM   265  C CG  . LEU   A 1 51  ? 105.845 93.535  99.583  1.00 74.08  ? 51  LEU   A CG  1 
ATOM   266  C CD1 . LEU   A 1 51  ? 104.631 94.306  100.055 1.00 74.08  ? 51  LEU   A CD1 1 
ATOM   267  C CD2 . LEU   A 1 51  ? 107.062 94.441  99.502  1.00 74.08  ? 51  LEU   A CD2 1 
ATOM   268  N N   . LEU   A 1 52  ? 105.534 89.903  98.643  1.00 71.85  ? 52  LEU   A N   1 
ATOM   269  C CA  . LEU   A 1 52  ? 105.248 89.336  97.330  1.00 71.85  ? 52  LEU   A CA  1 
ATOM   270  C C   . LEU   A 1 52  ? 104.044 88.402  97.380  1.00 71.85  ? 52  LEU   A C   1 
ATOM   271  O O   . LEU   A 1 52  ? 103.234 88.372  96.446  1.00 71.85  ? 52  LEU   A O   1 
ATOM   272  C CB  . LEU   A 1 52  ? 106.479 88.603  96.800  1.00 71.85  ? 52  LEU   A CB  1 
ATOM   273  C CG  . LEU   A 1 52  ? 106.386 88.013  95.394  1.00 71.85  ? 52  LEU   A CG  1 
ATOM   274  C CD1 . LEU   A 1 52  ? 106.001 89.088  94.391  1.00 71.85  ? 52  LEU   A CD1 1 
ATOM   275  C CD2 . LEU   A 1 52  ? 107.701 87.358  95.004  1.00 71.85  ? 52  LEU   A CD2 1 
ATOM   276  N N   . VAL   A 1 53  ? 103.910 87.636  98.466  1.00 66.33  ? 53  VAL   A N   1 
ATOM   277  C CA  . VAL   A 1 53  ? 102.758 86.754  98.626  1.00 66.33  ? 53  VAL   A CA  1 
ATOM   278  C C   . VAL   A 1 53  ? 101.474 87.567  98.743  1.00 66.33  ? 53  VAL   A C   1 
ATOM   279  O O   . VAL   A 1 53  ? 100.444 87.213  98.157  1.00 66.33  ? 53  VAL   A O   1 
ATOM   280  C CB  . VAL   A 1 53  ? 102.966 85.830  99.840  1.00 66.33  ? 53  VAL   A CB  1 
ATOM   281  C CG1 . VAL   A 1 53  ? 101.736 84.975  100.088 1.00 66.33  ? 53  VAL   A CG1 1 
ATOM   282  C CG2 . VAL   A 1 53  ? 104.188 84.954  99.627  1.00 66.33  ? 53  VAL   A CG2 1 
ATOM   283  N N   . GLY   A 1 54  ? 101.516 88.672  99.489  1.00 63.28  ? 54  GLY   A N   1 
ATOM   284  C CA  . GLY   A 1 54  ? 100.354 89.541  99.575  1.00 63.28  ? 54  GLY   A CA  1 
ATOM   285  C C   . GLY   A 1 54  ? 100.007 90.188  98.249  1.00 63.28  ? 54  GLY   A C   1 
ATOM   286  O O   . GLY   A 1 54  ? 98.829  90.340  97.914  1.00 63.28  ? 54  GLY   A O   1 
ATOM   287  N N   . GLY   A 1 55  ? 101.024 90.581  97.478  1.00 58.27  ? 55  GLY   A N   1 
ATOM   288  C CA  . GLY   A 1 55  ? 100.768 91.118  96.150  1.00 58.27  ? 55  GLY   A CA  1 
ATOM   289  C C   . GLY   A 1 55  ? 100.129 90.102  95.222  1.00 58.27  ? 55  GLY   A C   1 
ATOM   290  O O   . GLY   A 1 55  ? 99.195  90.423  94.483  1.00 58.27  ? 55  GLY   A O   1 
ATOM   291  N N   . PHE   A 1 56  ? 100.618 88.859  95.258  1.00 61.55  ? 56  PHE   A N   1 
ATOM   292  C CA  . PHE   A 1 56  ? 100.004 87.785  94.480  1.00 61.55  ? 56  PHE   A CA  1 
ATOM   293  C C   . PHE   A 1 56  ? 98.563  87.544  94.910  1.00 61.55  ? 56  PHE   A C   1 
ATOM   294  O O   . PHE   A 1 56  ? 97.675  87.358  94.068  1.00 61.55  ? 56  PHE   A O   1 
ATOM   295  C CB  . PHE   A 1 56  ? 100.817 86.501  94.636  1.00 61.55  ? 56  PHE   A CB  1 
ATOM   296  C CG  . PHE   A 1 56  ? 101.833 86.285  93.555  1.00 61.55  ? 56  PHE   A CG  1 
ATOM   297  C CD1 . PHE   A 1 56  ? 102.857 87.196  93.355  1.00 61.55  ? 56  PHE   A CD1 1 
ATOM   298  C CD2 . PHE   A 1 56  ? 101.770 85.163  92.746  1.00 61.55  ? 56  PHE   A CD2 1 
ATOM   299  C CE1 . PHE   A 1 56  ? 103.796 86.995  92.361  1.00 61.55  ? 56  PHE   A CE1 1 
ATOM   300  C CE2 . PHE   A 1 56  ? 102.704 84.956  91.752  1.00 61.55  ? 56  PHE   A CE2 1 
ATOM   301  C CZ  . PHE   A 1 56  ? 103.719 85.873  91.558  1.00 61.55  ? 56  PHE   A CZ  1 
ATOM   302  N N   . THR   A 1 57  ? 98.313  87.549  96.220  1.00 58.56  ? 57  THR   A N   1 
ATOM   303  C CA  . THR   A 1 57  ? 96.976  87.261  96.725  1.00 58.56  ? 57  THR   A CA  1 
ATOM   304  C C   . THR   A 1 57  ? 96.005  88.384  96.378  1.00 58.56  ? 57  THR   A C   1 
ATOM   305  O O   . THR   A 1 57  ? 94.825  88.132  96.109  1.00 58.56  ? 57  THR   A O   1 
ATOM   306  C CB  . THR   A 1 57  ? 97.040  87.029  98.236  1.00 58.56  ? 57  THR   A CB  1 
ATOM   307  O OG1 . THR   A 1 57  ? 97.992  85.996  98.512  1.00 58.56  ? 57  THR   A OG1 1 
ATOM   308  C CG2 . THR   A 1 57  ? 95.700  86.566  98.767  1.00 58.56  ? 57  THR   A CG2 1 
ATOM   309  N N   . MET   A 1 58  ? 96.483  89.633  96.367  1.00 56.47  ? 58  MET   A N   1 
ATOM   310  C CA  . MET   A 1 58  ? 95.629  90.742  95.956  1.00 56.47  ? 58  MET   A CA  1 
ATOM   311  C C   . MET   A 1 58  ? 95.402  90.744  94.450  1.00 56.47  ? 58  MET   A C   1 
ATOM   312  O O   . MET   A 1 58  ? 94.325  91.138  93.988  1.00 56.47  ? 58  MET   A O   1 
ATOM   313  C CB  . MET   A 1 58  ? 96.232  92.073  96.406  1.00 56.47  ? 58  MET   A CB  1 
ATOM   314  C CG  . MET   A 1 58  ? 95.346  93.281  96.129  1.00 56.47  ? 58  MET   A CG  1 
ATOM   315  S SD  . MET   A 1 58  ? 96.064  94.839  96.672  1.00 56.47  ? 58  MET   A SD  1 
ATOM   316  C CE  . MET   A 1 58  ? 95.920  94.680  98.446  1.00 56.47  ? 58  MET   A CE  1 
ATOM   317  N N   . THR   A 1 59  ? 96.399  90.313  93.671  1.00 50.87  ? 59  THR   A N   1 
ATOM   318  C CA  . THR   A 1 59  ? 96.205  90.161  92.233  1.00 50.87  ? 59  THR   A CA  1 
ATOM   319  C C   . THR   A 1 59  ? 95.155  89.101  91.935  1.00 50.87  ? 59  THR   A C   1 
ATOM   320  O O   . THR   A 1 59  ? 94.334  89.265  91.026  1.00 50.87  ? 59  THR   A O   1 
ATOM   321  C CB  . THR   A 1 59  ? 97.528  89.795  91.560  1.00 50.87  ? 59  THR   A CB  1 
ATOM   322  O OG1 . THR   A 1 59  ? 98.535  90.742  91.929  1.00 50.87  ? 59  THR   A OG1 1 
ATOM   323  C CG2 . THR   A 1 59  ? 97.381  89.792  90.048  1.00 50.87  ? 59  THR   A CG2 1 
ATOM   324  N N   . ALA   A 1 60  ? 95.159  88.009  92.704  1.00 50.77  ? 60  ALA   A N   1 
ATOM   325  C CA  . ALA   A 1 60  ? 94.243  86.902  92.455  1.00 50.77  ? 60  ALA   A CA  1 
ATOM   326  C C   . ALA   A 1 60  ? 92.783  87.262  92.709  1.00 50.77  ? 60  ALA   A C   1 
ATOM   327  O O   . ALA   A 1 60  ? 91.897  86.509  92.293  1.00 50.77  ? 60  ALA   A O   1 
ATOM   328  C CB  . ALA   A 1 60  ? 94.631  85.698  93.312  1.00 50.77  ? 60  ALA   A CB  1 
ATOM   329  N N   . THR   A 1 61  ? 92.508  88.378  93.387  1.00 50.84  ? 61  THR   A N   1 
ATOM   330  C CA  . THR   A 1 61  ? 91.122  88.790  93.592  1.00 50.84  ? 61  THR   A CA  1 
ATOM   331  C C   . THR   A 1 61  ? 90.485  89.255  92.287  1.00 50.84  ? 61  THR   A C   1 
ATOM   332  O O   . THR   A 1 61  ? 89.356  88.868  91.965  1.00 50.84  ? 61  THR   A O   1 
ATOM   333  C CB  . THR   A 1 61  ? 91.046  89.896  94.646  1.00 50.84  ? 61  THR   A CB  1 
ATOM   334  O OG1 . THR   A 1 61  ? 91.791  91.037  94.203  1.00 50.84  ? 61  THR   A OG1 1 
ATOM   335  C CG2 . THR   A 1 61  ? 91.604  89.411  95.976  1.00 50.84  ? 61  THR   A CG2 1 
ATOM   336  N N   . TRP   A 1 62  ? 91.195  90.085  91.521  1.00 50.11  ? 62  TRP   A N   1 
ATOM   337  C CA  . TRP   A 1 62  ? 90.645  90.593  90.268  1.00 50.11  ? 62  TRP   A CA  1 
ATOM   338  C C   . TRP   A 1 62  ? 90.824  89.603  89.125  1.00 50.11  ? 62  TRP   A C   1 
ATOM   339  O O   . TRP   A 1 62  ? 89.916  89.427  88.307  1.00 50.11  ? 62  TRP   A O   1 
ATOM   340  C CB  . TRP   A 1 62  ? 91.293  91.932  89.907  1.00 50.11  ? 62  TRP   A CB  1 
ATOM   341  C CG  . TRP   A 1 62  ? 90.542  93.157  90.374  1.00 50.11  ? 62  TRP   A CG  1 
ATOM   342  C CD1 . TRP   A 1 62  ? 91.059  94.211  91.068  1.00 50.11  ? 62  TRP   A CD1 1 
ATOM   343  C CD2 . TRP   A 1 62  ? 89.158  93.475  90.141  1.00 50.11  ? 62  TRP   A CD2 1 
ATOM   344  N NE1 . TRP   A 1 62  ? 90.086  95.150  91.304  1.00 50.11  ? 62  TRP   A NE1 1 
ATOM   345  C CE2 . TRP   A 1 62  ? 88.911  94.724  90.744  1.00 50.11  ? 62  TRP   A CE2 1 
ATOM   346  C CE3 . TRP   A 1 62  ? 88.104  92.822  89.489  1.00 50.11  ? 62  TRP   A CE3 1 
ATOM   347  C CZ2 . TRP   A 1 62  ? 87.657  95.331  90.718  1.00 50.11  ? 62  TRP   A CZ2 1 
ATOM   348  C CZ3 . TRP   A 1 62  ? 86.861  93.427  89.467  1.00 50.11  ? 62  TRP   A CZ3 1 
ATOM   349  C CH2 . TRP   A 1 62  ? 86.648  94.667  90.076  1.00 50.11  ? 62  TRP   A CH2 1 
ATOM   350  N N   . VAL   A 1 63  ? 91.979  88.951  89.051  1.00 42.29  ? 63  VAL   A N   1 
ATOM   351  C CA  . VAL   A 1 63  ? 92.281  88.061  87.936  1.00 42.29  ? 63  VAL   A CA  1 
ATOM   352  C C   . VAL   A 1 63  ? 91.560  86.736  88.140  1.00 42.29  ? 63  VAL   A C   1 
ATOM   353  O O   . VAL   A 1 63  ? 91.634  86.129  89.214  1.00 42.29  ? 63  VAL   A O   1 
ATOM   354  C CB  . VAL   A 1 63  ? 93.797  87.857  87.798  1.00 42.29  ? 63  VAL   A CB  1 
ATOM   355  C CG1 . VAL   A 1 63  ? 94.110  87.010  86.581  1.00 42.29  ? 63  VAL   A CG1 1 
ATOM   356  C CG2 . VAL   A 1 63  ? 94.494  89.198  87.698  1.00 42.29  ? 63  VAL   A CG2 1 
ATOM   357  N N   . GLY   A 1 64  ? 90.863  86.290  87.108  1.00 41.53  ? 64  GLY   A N   1 
ATOM   358  C CA  . GLY   A 1 64  ? 90.115  85.057  87.186  1.00 41.53  ? 64  GLY   A CA  1 
ATOM   359  C C   . GLY   A 1 64  ? 89.596  84.674  85.823  1.00 41.53  ? 64  GLY   A C   1 
ATOM   360  O O   . GLY   A 1 64  ? 90.145  85.083  84.799  1.00 41.53  ? 64  GLY   A O   1 
ATOM   361  N N   . GLY   A 1 65  ? 88.530  83.874  85.818  1.00 37.65  ? 65  GLY   A N   1 
ATOM   362  C CA  . GLY   A 1 65  ? 87.920  83.486  84.556  1.00 37.65  ? 65  GLY   A CA  1 
ATOM   363  C C   . GLY   A 1 65  ? 87.299  84.659  83.823  1.00 37.65  ? 65  GLY   A C   1 
ATOM   364  O O   . GLY   A 1 65  ? 87.470  84.803  82.607  1.00 37.65  ? 65  GLY   A O   1 
ATOM   365  N N   . GLY   A 1 66  ? 86.580  85.515  84.553  1.00 36.75  ? 66  GLY   A N   1 
ATOM   366  C CA  . GLY   A 1 66  ? 85.952  86.667  83.930  1.00 36.75  ? 66  GLY   A CA  1 
ATOM   367  C C   . GLY   A 1 66  ? 86.955  87.633  83.332  1.00 36.75  ? 66  GLY   A C   1 
ATOM   368  O O   . GLY   A 1 66  ? 86.760  88.126  82.223  1.00 36.75  ? 66  GLY   A O   1 
ATOM   369  N N   . TYR   A 1 67  ? 88.056  87.883  84.045  1.00 35.97  ? 67  TYR   A N   1 
ATOM   370  C CA  . TYR   A 1 67  ? 89.081  88.815  83.581  1.00 35.97  ? 67  TYR   A CA  1 
ATOM   371  C C   . TYR   A 1 67  ? 89.682  88.369  82.251  1.00 35.97  ? 67  TYR   A C   1 
ATOM   372  O O   . TYR   A 1 67  ? 89.651  89.109  81.257  1.00 35.97  ? 67  TYR   A O   1 
ATOM   373  C CB  . TYR   A 1 67  ? 90.161  88.937  84.662  1.00 35.97  ? 67  TYR   A CB  1 
ATOM   374  C CG  . TYR   A 1 67  ? 91.243  89.972  84.430  1.00 35.97  ? 67  TYR   A CG  1 
ATOM   375  C CD1 . TYR   A 1 67  ? 92.355  89.684  83.648  1.00 35.97  ? 67  TYR   A CD1 1 
ATOM   376  C CD2 . TYR   A 1 67  ? 91.169  91.225  85.022  1.00 35.97  ? 67  TYR   A CD2 1 
ATOM   377  C CE1 . TYR   A 1 67  ? 93.347  90.617  83.445  1.00 35.97  ? 67  TYR   A CE1 1 
ATOM   378  C CE2 . TYR   A 1 67  ? 92.158  92.165  84.824  1.00 35.97  ? 67  TYR   A CE2 1 
ATOM   379  C CZ  . TYR   A 1 67  ? 93.244  91.855  84.035  1.00 35.97  ? 67  TYR   A CZ  1 
ATOM   380  O OH  . TYR   A 1 67  ? 94.234  92.785  83.834  1.00 35.97  ? 67  TYR   A OH  1 
ATOM   381  N N   . ILE   A 1 68  ? 90.207  87.144  82.205  1.00 35.31  ? 68  ILE   A N   1 
ATOM   382  C CA  . ILE   A 1 68  ? 90.904  86.685  81.008  1.00 35.31  ? 68  ILE   A CA  1 
ATOM   383  C C   . ILE   A 1 68  ? 89.920  86.431  79.869  1.00 35.31  ? 68  ILE   A C   1 
ATOM   384  O O   . ILE   A 1 68  ? 90.212  86.739  78.705  1.00 35.31  ? 68  ILE   A O   1 
ATOM   385  C CB  . ILE   A 1 68  ? 91.779  85.455  81.328  1.00 35.31  ? 68  ILE   A CB  1 
ATOM   386  C CG1 . ILE   A 1 68  ? 90.948  84.263  81.804  1.00 35.31  ? 68  ILE   A CG1 1 
ATOM   387  C CG2 . ILE   A 1 68  ? 92.821  85.805  82.377  1.00 35.31  ? 68  ILE   A CG2 1 
ATOM   388  C CD1 . ILE   A 1 68  ? 91.718  82.963  81.851  1.00 35.31  ? 68  ILE   A CD1 1 
ATOM   389  N N   . ASN   A 1 69  ? 88.733  85.895  80.179  1.00 36.16  ? 69  ASN   A N   1 
ATOM   390  C CA  . ASN   A 1 69  ? 87.742  85.656  79.134  1.00 36.16  ? 69  ASN   A CA  1 
ATOM   391  C C   . ASN   A 1 69  ? 87.236  86.964  78.538  1.00 36.16  ? 69  ASN   A C   1 
ATOM   392  O O   . ASN   A 1 69  ? 87.081  87.071  77.316  1.00 36.16  ? 69  ASN   A O   1 
ATOM   393  C CB  . ASN   A 1 69  ? 86.586  84.825  79.686  1.00 36.16  ? 69  ASN   A CB  1 
ATOM   394  C CG  . ASN   A 1 69  ? 86.831  83.334  79.566  1.00 36.16  ? 69  ASN   A CG  1 
ATOM   395  O OD1 . ASN   A 1 69  ? 87.918  82.845  79.866  1.00 36.16  ? 69  ASN   A OD1 1 
ATOM   396  N ND2 . ASN   A 1 69  ? 85.818  82.604  79.121  1.00 36.16  ? 69  ASN   A ND2 1 
ATOM   397  N N   . GLY   A 1 70  ? 86.993  87.976  79.375  1.00 33.74  ? 70  GLY   A N   1 
ATOM   398  C CA  . GLY   A 1 70  ? 86.569  89.265  78.863  1.00 33.74  ? 70  GLY   A CA  1 
ATOM   399  C C   . GLY   A 1 70  ? 87.642  89.957  78.048  1.00 33.74  ? 70  GLY   A C   1 
ATOM   400  O O   . GLY   A 1 70  ? 87.344  90.576  77.025  1.00 33.74  ? 70  GLY   A O   1 
ATOM   401  N N   . THR   A 1 71  ? 88.901  89.867  78.486  1.00 32.60  ? 71  THR   A N   1 
ATOM   402  C CA  . THR   A 1 71  ? 89.990  90.465  77.717  1.00 32.60  ? 71  THR   A CA  1 
ATOM   403  C C   . THR   A 1 71  ? 90.123  89.804  76.349  1.00 32.60  ? 71  THR   A C   1 
ATOM   404  O O   . THR   A 1 71  ? 90.249  90.487  75.322  1.00 32.60  ? 71  THR   A O   1 
ATOM   405  C CB  . THR   A 1 71  ? 91.300  90.360  78.496  1.00 32.60  ? 71  THR   A CB  1 
ATOM   406  O OG1 . THR   A 1 71  ? 91.135  90.950  79.791  1.00 32.60  ? 71  THR   A OG1 1 
ATOM   407  C CG2 . THR   A 1 71  ? 92.410  91.084  77.763  1.00 32.60  ? 71  THR   A CG2 1 
ATOM   408  N N   . ALA   A 1 72  ? 90.072  88.468  76.314  1.00 33.72  ? 72  ALA   A N   1 
ATOM   409  C CA  . ALA   A 1 72  ? 90.174  87.756  75.044  1.00 33.72  ? 72  ALA   A CA  1 
ATOM   410  C C   . ALA   A 1 72  ? 88.988  88.064  74.138  1.00 33.72  ? 72  ALA   A C   1 
ATOM   411  O O   . ALA   A 1 72  ? 89.153  88.223  72.923  1.00 33.72  ? 72  ALA   A O   1 
ATOM   412  C CB  . ALA   A 1 72  ? 90.288  86.254  75.294  1.00 33.72  ? 72  ALA   A CB  1 
ATOM   413  N N   . GLU   A 1 73  ? 87.784  88.157  74.711  1.00 38.56  ? 73  GLU   A N   1 
ATOM   414  C CA  . GLU   A 1 73  ? 86.606  88.497  73.920  1.00 38.56  ? 73  GLU   A CA  1 
ATOM   415  C C   . GLU   A 1 73  ? 86.699  89.908  73.356  1.00 38.56  ? 73  GLU   A C   1 
ATOM   416  O O   . GLU   A 1 73  ? 86.346  90.143  72.195  1.00 38.56  ? 73  GLU   A O   1 
ATOM   417  C CB  . GLU   A 1 73  ? 85.347  88.346  74.771  1.00 38.56  ? 73  GLU   A CB  1 
ATOM   418  C CG  . GLU   A 1 73  ? 84.060  88.628  74.028  1.00 38.56  ? 73  GLU   A CG  1 
ATOM   419  C CD  . GLU   A 1 73  ? 82.939  89.038  74.955  1.00 38.56  ? 73  GLU   A CD  1 
ATOM   420  O OE1 . GLU   A 1 73  ? 83.135  88.973  76.185  1.00 38.56  ? 73  GLU   A OE1 1 
ATOM   421  O OE2 . GLU   A 1 73  ? 81.862  89.424  74.457  1.00 38.56  ? 73  GLU   A OE2 1 
ATOM   422  N N   . ALA   A 1 74  ? 87.166  90.863  74.165  1.00 35.64  ? 74  ALA   A N   1 
ATOM   423  C CA  . ALA   A 1 74  ? 87.277  92.243  73.705  1.00 35.64  ? 74  ALA   A CA  1 
ATOM   424  C C   . ALA   A 1 74  ? 88.295  92.375  72.583  1.00 35.64  ? 74  ALA   A C   1 
ATOM   425  O O   . ALA   A 1 74  ? 88.074  93.119  71.622  1.00 35.64  ? 74  ALA   A O   1 
ATOM   426  C CB  . ALA   A 1 74  ? 87.647  93.157  74.869  1.00 35.64  ? 74  ALA   A CB  1 
ATOM   427  N N   . VAL   A 1 75  ? 89.424  91.669  72.689  1.00 32.17  ? 75  VAL   A N   1 
ATOM   428  C CA  . VAL   A 1 75  ? 90.391  91.708  71.596  1.00 32.17  ? 75  VAL   A CA  1 
ATOM   429  C C   . VAL   A 1 75  ? 89.855  90.967  70.370  1.00 32.17  ? 75  VAL   A C   1 
ATOM   430  O O   . VAL   A 1 75  ? 90.148  91.346  69.229  1.00 32.17  ? 75  VAL   A O   1 
ATOM   431  C CB  . VAL   A 1 75  ? 91.749  91.155  72.069  1.00 32.17  ? 75  VAL   A CB  1 
ATOM   432  C CG1 . VAL   A 1 75  ? 92.781  91.203  70.955  1.00 32.17  ? 75  VAL   A CG1 1 
ATOM   433  C CG2 . VAL   A 1 75  ? 92.249  91.949  73.258  1.00 32.17  ? 75  VAL   A CG2 1 
ATOM   434  N N   . TYR   A 1 76  ? 89.034  89.934  70.576  1.00 38.90  ? 76  TYR   A N   1 
ATOM   435  C CA  . TYR   A 1 76  ? 88.617  89.080  69.466  1.00 38.90  ? 76  TYR   A CA  1 
ATOM   436  C C   . TYR   A 1 76  ? 87.577  89.750  68.571  1.00 38.90  ? 76  TYR   A C   1 
ATOM   437  O O   . TYR   A 1 76  ? 87.600  89.563  67.349  1.00 38.90  ? 76  TYR   A O   1 
ATOM   438  C CB  . TYR   A 1 76  ? 88.077  87.756  70.003  1.00 38.90  ? 76  TYR   A CB  1 
ATOM   439  C CG  . TYR   A 1 76  ? 87.524  86.851  68.930  1.00 38.90  ? 76  TYR   A CG  1 
ATOM   440  C CD1 . TYR   A 1 76  ? 88.322  86.422  67.882  1.00 38.90  ? 76  TYR   A CD1 1 
ATOM   441  C CD2 . TYR   A 1 76  ? 86.203  86.431  68.962  1.00 38.90  ? 76  TYR   A CD2 1 
ATOM   442  C CE1 . TYR   A 1 76  ? 87.823  85.601  66.898  1.00 38.90  ? 76  TYR   A CE1 1 
ATOM   443  C CE2 . TYR   A 1 76  ? 85.695  85.607  67.981  1.00 38.90  ? 76  TYR   A CE2 1 
ATOM   444  C CZ  . TYR   A 1 76  ? 86.511  85.195  66.952  1.00 38.90  ? 76  TYR   A CZ  1 
ATOM   445  O OH  . TYR   A 1 76  ? 86.016  84.375  65.968  1.00 38.90  ? 76  TYR   A OH  1 
ATOM   446  N N   . VAL   A 1 77  ? 86.653  90.509  69.153  1.00 42.91  ? 77  VAL   A N   1 
ATOM   447  C CA  . VAL   A 1 77  ? 85.507  91.046  68.400  1.00 42.91  ? 77  VAL   A CA  1 
ATOM   448  C C   . VAL   A 1 77  ? 86.002  92.042  67.354  1.00 42.91  ? 77  VAL   A C   1 
ATOM   449  O O   . VAL   A 1 77  ? 86.766  92.963  67.694  1.00 42.91  ? 77  VAL   A O   1 
ATOM   450  C CB  . VAL   A 1 77  ? 84.502  91.693  69.353  1.00 42.91  ? 77  VAL   A CB  1 
ATOM   451  C CG1 . VAL   A 1 77  ? 83.443  92.456  68.582  1.00 42.91  ? 77  VAL   A CG1 1 
ATOM   452  C CG2 . VAL   A 1 77  ? 83.844  90.634  70.215  1.00 42.91  ? 77  VAL   A CG2 1 
ATOM   453  N N   . PRO   A 1 78  ? 85.610  91.892  66.082  1.00 48.23  ? 78  PRO   A N   1 
ATOM   454  C CA  . PRO   A 1 78  ? 86.206  92.714  65.012  1.00 48.23  ? 78  PRO   A CA  1 
ATOM   455  C C   . PRO   A 1 78  ? 85.952  94.207  65.137  1.00 48.23  ? 78  PRO   A C   1 
ATOM   456  O O   . PRO   A 1 78  ? 86.821  95.004  64.763  1.00 48.23  ? 78  PRO   A O   1 
ATOM   457  C CB  . PRO   A 1 78  ? 85.552  92.147  63.743  1.00 48.23  ? 78  PRO   A CB  1 
ATOM   458  C CG  . PRO   A 1 78  ? 85.139  90.766  64.120  1.00 48.23  ? 78  PRO   A CG  1 
ATOM   459  C CD  . PRO   A 1 78  ? 84.684  90.886  65.537  1.00 48.23  ? 78  PRO   A CD  1 
ATOM   460  N N   . GLY   A 1 79  ? 84.788  94.615  65.642  1.00 49.83  ? 79  GLY   A N   1 
ATOM   461  C CA  . GLY   A 1 79  ? 84.477  96.031  65.710  1.00 49.83  ? 79  GLY   A CA  1 
ATOM   462  C C   . GLY   A 1 79  ? 85.212  96.778  66.800  1.00 49.83  ? 79  GLY   A C   1 
ATOM   463  O O   . GLY   A 1 79  ? 85.239  98.012  66.780  1.00 49.83  ? 79  GLY   A O   1 
ATOM   464  N N   . TYR   A 1 80  ? 85.804  96.061  67.753  1.00 50.58  ? 80  TYR   A N   1 
ATOM   465  C CA  . TYR   A 1 80  ? 86.358  96.668  68.955  1.00 50.58  ? 80  TYR   A CA  1 
ATOM   466  C C   . TYR   A 1 80  ? 87.872  96.526  69.047  1.00 50.58  ? 80  TYR   A C   1 
ATOM   467  O O   . TYR   A 1 80  ? 88.579  97.533  69.135  1.00 50.58  ? 80  TYR   A O   1 
ATOM   468  C CB  . TYR   A 1 80  ? 85.652  96.045  70.164  1.00 50.58  ? 80  TYR   A CB  1 
ATOM   469  C CG  . TYR   A 1 80  ? 84.194  96.442  70.225  1.00 50.58  ? 80  TYR   A CG  1 
ATOM   470  C CD1 . TYR   A 1 80  ? 83.791  97.716  69.850  1.00 50.58  ? 80  TYR   A CD1 1 
ATOM   471  C CD2 . TYR   A 1 80  ? 83.213  95.524  70.572  1.00 50.58  ? 80  TYR   A CD2 1 
ATOM   472  C CE1 . TYR   A 1 80  ? 82.461  98.084  69.885  1.00 50.58  ? 80  TYR   A CE1 1 
ATOM   473  C CE2 . TYR   A 1 80  ? 81.880  95.882  70.610  1.00 50.58  ? 80  TYR   A CE2 1 
ATOM   474  C CZ  . TYR   A 1 80  ? 81.509  97.161  70.262  1.00 50.58  ? 80  TYR   A CZ  1 
ATOM   475  O OH  . TYR   A 1 80  ? 80.182  97.522  70.291  1.00 50.58  ? 80  TYR   A OH  1 
ATOM   476  N N   . GLY   A 1 81  ? 88.397  95.304  69.014  1.00 39.57  ? 81  GLY   A N   1 
ATOM   477  C CA  . GLY   A 1 81  ? 89.835  95.114  69.018  1.00 39.57  ? 81  GLY   A CA  1 
ATOM   478  C C   . GLY   A 1 81  ? 90.496  95.442  70.350  1.00 39.57  ? 81  GLY   A C   1 
ATOM   479  O O   . GLY   A 1 81  ? 89.855  95.583  71.390  1.00 39.57  ? 81  GLY   A O   1 
ATOM   480  N N   . LEU   A 1 82  ? 91.825  95.568  70.290  1.00 37.39  ? 82  LEU   A N   1 
ATOM   481  C CA  . LEU   A 1 82  ? 92.608  95.844  71.492  1.00 37.39  ? 82  LEU   A CA  1 
ATOM   482  C C   . LEU   A 1 82  ? 92.409  97.273  71.988  1.00 37.39  ? 82  LEU   A C   1 
ATOM   483  O O   . LEU   A 1 82  ? 92.439  97.512  73.201  1.00 37.39  ? 82  LEU   A O   1 
ATOM   484  C CB  . LEU   A 1 82  ? 94.091  95.570  71.228  1.00 37.39  ? 82  LEU   A CB  1 
ATOM   485  C CG  . LEU   A 1 82  ? 95.132  96.042  72.250  1.00 37.39  ? 82  LEU   A CG  1 
ATOM   486  C CD1 . LEU   A 1 82  ? 94.911  95.398  73.608  1.00 37.39  ? 82  LEU   A CD1 1 
ATOM   487  C CD2 . LEU   A 1 82  ? 96.540  95.766  71.757  1.00 37.39  ? 82  LEU   A CD2 1 
ATOM   488  N N   . ALA   A 1 83  ? 92.197  98.227  71.076  1.00 38.36  ? 83  ALA   A N   1 
ATOM   489  C CA  . ALA   A 1 83  ? 92.048  99.625  71.475  1.00 38.36  ? 83  ALA   A CA  1 
ATOM   490  C C   . ALA   A 1 83  ? 90.820  99.845  72.347  1.00 38.36  ? 83  ALA   A C   1 
ATOM   491  O O   . ALA   A 1 83  ? 90.775  100.806 73.122  1.00 38.36  ? 83  ALA   A O   1 
ATOM   492  C CB  . ALA   A 1 83  ? 91.979  100.523 70.240  1.00 38.36  ? 83  ALA   A CB  1 
ATOM   493  N N   . TRP   A 1 84  ? 89.819  98.976  72.236  1.00 42.10  ? 84  TRP   A N   1 
ATOM   494  C CA  . TRP   A 1 84  ? 88.625  99.053  73.063  1.00 42.10  ? 84  TRP   A CA  1 
ATOM   495  C C   . TRP   A 1 84  ? 88.633  98.055  74.212  1.00 42.10  ? 84  TRP   A C   1 
ATOM   496  O O   . TRP   A 1 84  ? 87.677  98.023  74.992  1.00 42.10  ? 84  TRP   A O   1 
ATOM   497  C CB  . TRP   A 1 84  ? 87.378  98.854  72.199  1.00 42.10  ? 84  TRP   A CB  1 
ATOM   498  C CG  . TRP   A 1 84  ? 87.064  100.053 71.364  1.00 42.10  ? 84  TRP   A CG  1 
ATOM   499  C CD1 . TRP   A 1 84  ? 87.408  100.258 70.062  1.00 42.10  ? 84  TRP   A CD1 1 
ATOM   500  C CD2 . TRP   A 1 84  ? 86.354  101.222 71.780  1.00 42.10  ? 84  TRP   A CD2 1 
ATOM   501  N NE1 . TRP   A 1 84  ? 86.950  101.480 69.638  1.00 42.10  ? 84  TRP   A NE1 1 
ATOM   502  C CE2 . TRP   A 1 84  ? 86.300  102.092 70.676  1.00 42.10  ? 84  TRP   A CE2 1 
ATOM   503  C CE3 . TRP   A 1 84  ? 85.756  101.616 72.979  1.00 42.10  ? 84  TRP   A CE3 1 
ATOM   504  C CZ2 . TRP   A 1 84  ? 85.671  103.332 70.734  1.00 42.10  ? 84  TRP   A CZ2 1 
ATOM   505  C CZ3 . TRP   A 1 84  ? 85.133  102.847 73.036  1.00 42.10  ? 84  TRP   A CZ3 1 
ATOM   506  C CH2 . TRP   A 1 84  ? 85.095  103.690 71.920  1.00 42.10  ? 84  TRP   A CH2 1 
ATOM   507  N N   . ALA   A 1 85  ? 89.685  97.244  74.337  1.00 39.23  ? 85  ALA   A N   1 
ATOM   508  C CA  . ALA   A 1 85  ? 89.856  96.349  75.482  1.00 39.23  ? 85  ALA   A CA  1 
ATOM   509  C C   . ALA   A 1 85  ? 90.451  97.143  76.645  1.00 39.23  ? 85  ALA   A C   1 
ATOM   510  O O   . ALA   A 1 85  ? 91.619  97.003  77.014  1.00 39.23  ? 85  ALA   A O   1 
ATOM   511  C CB  . ALA   A 1 85  ? 90.731  95.162  75.110  1.00 39.23  ? 85  ALA   A CB  1 
ATOM   512  N N   . GLN   A 1 86  ? 89.613  97.995  77.229  1.00 40.15  ? 86  GLN   A N   1 
ATOM   513  C CA  . GLN   A 1 86  ? 90.073  98.940  78.236  1.00 40.15  ? 86  GLN   A CA  1 
ATOM   514  C C   . GLN   A 1 86  ? 89.937  98.429  79.660  1.00 40.15  ? 86  GLN   A C   1 
ATOM   515  O O   . GLN   A 1 86  ? 90.530  99.021  80.568  1.00 40.15  ? 86  GLN   A O   1 
ATOM   516  C CB  . GLN   A 1 86  ? 89.302  100.255 78.122  1.00 40.15  ? 86  GLN   A CB  1 
ATOM   517  C CG  . GLN   A 1 86  ? 88.868  100.623 76.724  1.00 40.15  ? 86  GLN   A CG  1 
ATOM   518  C CD  . GLN   A 1 86  ? 87.950  101.822 76.721  1.00 40.15  ? 86  GLN   A CD  1 
ATOM   519  O OE1 . GLN   A 1 86  ? 87.189  102.031 77.662  1.00 40.15  ? 86  GLN   A OE1 1 
ATOM   520  N NE2 . GLN   A 1 86  ? 88.015  102.616 75.665  1.00 40.15  ? 86  GLN   A NE2 1 
ATOM   521  N N   . ALA   A 1 87  ? 89.162  97.369  79.881  1.00 36.42  ? 87  ALA   A N   1 
ATOM   522  C CA  . ALA   A 1 87  ? 88.916  96.904  81.245  1.00 36.42  ? 87  ALA   A CA  1 
ATOM   523  C C   . ALA   A 1 87  ? 90.167  96.401  81.962  1.00 36.42  ? 87  ALA   A C   1 
ATOM   524  O O   . ALA   A 1 87  ? 90.348  96.763  83.136  1.00 36.42  ? 87  ALA   A O   1 
ATOM   525  C CB  . ALA   A 1 87  ? 87.794  95.859  81.241  1.00 36.42  ? 87  ALA   A CB  1 
ATOM   526  N N   . PRO   A 1 88  ? 91.054  95.584  81.364  1.00 34.82  ? 88  PRO   A N   1 
ATOM   527  C CA  . PRO   A 1 88  ? 92.282  95.218  82.104  1.00 34.82  ? 88  PRO   A CA  1 
ATOM   528  C C   . PRO   A 1 88  ? 93.171  96.406  82.446  1.00 34.82  ? 88  PRO   A C   1 
ATOM   529  O O   . PRO   A 1 88  ? 93.594  96.554  83.604  1.00 34.82  ? 88  PRO   A O   1 
ATOM   530  C CB  . PRO   A 1 88  ? 92.989  94.236  81.157  1.00 34.82  ? 88  PRO   A CB  1 
ATOM   531  C CG  . PRO   A 1 88  ? 92.312  94.360  79.856  1.00 34.82  ? 88  PRO   A CG  1 
ATOM   532  C CD  . PRO   A 1 88  ? 90.924  94.778  80.135  1.00 34.82  ? 88  PRO   A CD  1 
ATOM   533  N N   . ILE   A 1 89  ? 93.462  97.261  81.463  1.00 38.79  ? 89  ILE   A N   1 
ATOM   534  C CA  . ILE   A 1 89  ? 94.285  98.442  81.709  1.00 38.79  ? 89  ILE   A CA  1 
ATOM   535  C C   . ILE   A 1 89  ? 93.572  99.395  82.658  1.00 38.79  ? 89  ILE   A C   1 
ATOM   536  O O   . ILE   A 1 89  ? 94.195  100.002 83.541  1.00 38.79  ? 89  ILE   A O   1 
ATOM   537  C CB  . ILE   A 1 89  ? 94.638  99.132  80.377  1.00 38.79  ? 89  ILE   A CB  1 
ATOM   538  C CG1 . ILE   A 1 89  ? 95.199  98.122  79.372  1.00 38.79  ? 89  ILE   A CG1 1 
ATOM   539  C CG2 . ILE   A 1 89  ? 95.632  100.257 80.605  1.00 38.79  ? 89  ILE   A CG2 1 
ATOM   540  C CD1 . ILE   A 1 89  ? 96.376  97.318  79.884  1.00 38.79  ? 89  ILE   A CD1 1 
ATOM   541  N N   . GLY   A 1 90  ? 92.255  99.535  82.495  1.00 36.62  ? 90  GLY   A N   1 
ATOM   542  C CA  . GLY   A 1 90  ? 91.492  100.401 83.377  1.00 36.62  ? 90  GLY   A CA  1 
ATOM   543  C C   . GLY   A 1 90  ? 91.511  99.936  84.819  1.00 36.62  ? 90  GLY   A C   1 
ATOM   544  O O   . GLY   A 1 90  ? 91.621  100.747 85.736  1.00 36.62  ? 90  GLY   A O   1 
ATOM   545  N N   . TYR   A 1 91  ? 91.434  98.625  85.040  1.00 42.75  ? 91  TYR   A N   1 
ATOM   546  C CA  . TYR   A 1 91  ? 91.458  98.112  86.406  1.00 42.75  ? 91  TYR   A CA  1 
ATOM   547  C C   . TYR   A 1 91  ? 92.860  98.132  87.004  1.00 42.75  ? 91  TYR   A C   1 
ATOM   548  O O   . TYR   A 1 91  ? 93.005  98.319  88.217  1.00 42.75  ? 91  TYR   A O   1 
ATOM   549  C CB  . TYR   A 1 91  ? 90.868  96.703  86.448  1.00 42.75  ? 91  TYR   A CB  1 
ATOM   550  C CG  . TYR   A 1 91  ? 89.359  96.709  86.388  1.00 42.75  ? 91  TYR   A CG  1 
ATOM   551  C CD1 . TYR   A 1 91  ? 88.618  97.558  87.194  1.00 42.75  ? 91  TYR   A CD1 1 
ATOM   552  C CD2 . TYR   A 1 91  ? 88.674  95.875  85.521  1.00 42.75  ? 91  TYR   A CD2 1 
ATOM   553  C CE1 . TYR   A 1 91  ? 87.240  97.572  87.136  1.00 42.75  ? 91  TYR   A CE1 1 
ATOM   554  C CE2 . TYR   A 1 91  ? 87.301  95.893  85.455  1.00 42.75  ? 91  TYR   A CE2 1 
ATOM   555  C CZ  . TYR   A 1 91  ? 86.588  96.736  86.268  1.00 42.75  ? 91  TYR   A CZ  1 
ATOM   556  O OH  . TYR   A 1 91  ? 85.215  96.744  86.207  1.00 42.75  ? 91  TYR   A OH  1 
ATOM   557  N N   . SER   A 1 92  ? 93.898  97.964  86.181  1.00 40.34  ? 92  SER   A N   1 
ATOM   558  C CA  . SER   A 1 92  ? 95.260  98.156  86.672  1.00 40.34  ? 92  SER   A CA  1 
ATOM   559  C C   . SER   A 1 92  ? 95.484  99.599  87.114  1.00 40.34  ? 92  SER   A C   1 
ATOM   560  O O   . SER   A 1 92  ? 96.051  99.858  88.186  1.00 40.34  ? 92  SER   A O   1 
ATOM   561  C CB  . SER   A 1 92  ? 96.263  97.758  85.592  1.00 40.34  ? 92  SER   A CB  1 
ATOM   562  O OG  . SER   A 1 92  ? 96.164  96.377  85.293  1.00 40.34  ? 92  SER   A OG  1 
ATOM   563  N N   . LEU   A 1 93  ? 95.022  100.558 86.307  1.00 37.09  ? 93  LEU   A N   1 
ATOM   564  C CA  . LEU   A 1 93  ? 95.119  101.956 86.712  1.00 37.09  ? 93  LEU   A CA  1 
ATOM   565  C C   . LEU   A 1 93  ? 94.209  102.263 87.894  1.00 37.09  ? 93  LEU   A C   1 
ATOM   566  O O   . LEU   A 1 93  ? 94.515  103.156 88.688  1.00 37.09  ? 93  LEU   A O   1 
ATOM   567  C CB  . LEU   A 1 93  ? 94.797  102.875 85.537  1.00 37.09  ? 93  LEU   A CB  1 
ATOM   568  C CG  . LEU   A 1 93  ? 95.800  102.823 84.387  1.00 37.09  ? 93  LEU   A CG  1 
ATOM   569  C CD1 . LEU   A 1 93  ? 95.320  103.660 83.218  1.00 37.09  ? 93  LEU   A CD1 1 
ATOM   570  C CD2 . LEU   A 1 93  ? 97.160  103.295 84.864  1.00 37.09  ? 93  LEU   A CD2 1 
ATOM   571  N N   . SER   A 1 94  ? 93.101  101.534 88.034  1.00 40.33  ? 94  SER   A N   1 
ATOM   572  C CA  . SER   A 1 94  ? 92.259  101.677 89.215  1.00 40.33  ? 94  SER   A CA  1 
ATOM   573  C C   . SER   A 1 94  ? 92.996  101.238 90.470  1.00 40.33  ? 94  SER   A C   1 
ATOM   574  O O   . SER   A 1 94  ? 92.897  101.888 91.515  1.00 40.33  ? 94  SER   A O   1 
ATOM   575  C CB  . SER   A 1 94  ? 90.976  100.867 89.045  1.00 40.33  ? 94  SER   A CB  1 
ATOM   576  O OG  . SER   A 1 94  ? 91.186  99.511  89.392  1.00 40.33  ? 94  SER   A OG  1 
ATOM   577  N N   . LEU   A 1 95  ? 93.738  100.132 90.384  1.00 42.07  ? 95  LEU   A N   1 
ATOM   578  C CA  . LEU   A 1 95  ? 94.549  99.686  91.515  1.00 42.07  ? 95  LEU   A CA  1 
ATOM   579  C C   . LEU   A 1 95  ? 95.640  100.699 91.847  1.00 42.07  ? 95  LEU   A C   1 
ATOM   580  O O   . LEU   A 1 95  ? 95.889  100.993 93.025  1.00 42.07  ? 95  LEU   A O   1 
ATOM   581  C CB  . LEU   A 1 95  ? 95.158  98.317  91.214  1.00 42.07  ? 95  LEU   A CB  1 
ATOM   582  C CG  . LEU   A 1 95  ? 94.246  97.113  91.450  1.00 42.07  ? 95  LEU   A CG  1 
ATOM   583  C CD1 . LEU   A 1 95  ? 94.790  95.880  90.756  1.00 42.07  ? 95  LEU   A CD1 1 
ATOM   584  C CD2 . LEU   A 1 95  ? 94.082  96.854  92.932  1.00 42.07  ? 95  LEU   A CD2 1 
ATOM   585  N N   . ILE   A 1 96  ? 96.294  101.250 90.819  1.00 41.18  ? 96  ILE   A N   1 
ATOM   586  C CA  . ILE   A 1 96  ? 97.332  102.258 91.042  1.00 41.18  ? 96  ILE   A CA  1 
ATOM   587  C C   . ILE   A 1 96  ? 96.742  103.499 91.707  1.00 41.18  ? 96  ILE   A C   1 
ATOM   588  O O   . ILE   A 1 96  ? 97.301  104.033 92.673  1.00 41.18  ? 96  ILE   A O   1 
ATOM   589  C CB  . ILE   A 1 96  ? 98.040  102.605 89.719  1.00 41.18  ? 96  ILE   A CB  1 
ATOM   590  C CG1 . ILE   A 1 96  ? 99.069  101.533 89.370  1.00 41.18  ? 96  ILE   A CG1 1 
ATOM   591  C CG2 . ILE   A 1 96  ? 98.725  103.957 89.801  1.00 41.18  ? 96  ILE   A CG2 1 
ATOM   592  C CD1 . ILE   A 1 96  ? 99.514  101.559 87.930  1.00 41.18  ? 96  ILE   A CD1 1 
ATOM   593  N N   . LEU   A 1 97  ? 95.596  103.969 91.206  1.00 44.82  ? 97  LEU   A N   1 
ATOM   594  C CA  . LEU   A 1 97  ? 94.954  105.151 91.772  1.00 44.82  ? 97  LEU   A CA  1 
ATOM   595  C C   . LEU   A 1 97  ? 94.473  104.899 93.192  1.00 44.82  ? 97  LEU   A C   1 
ATOM   596  O O   . LEU   A 1 97  ? 94.549  105.792 94.043  1.00 44.82  ? 97  LEU   A O   1 
ATOM   597  C CB  . LEU   A 1 97  ? 93.786  105.591 90.895  1.00 44.82  ? 97  LEU   A CB  1 
ATOM   598  C CG  . LEU   A 1 97  ? 94.120  106.493 89.713  1.00 44.82  ? 97  LEU   A CG  1 
ATOM   599  C CD1 . LEU   A 1 97  ? 92.873  106.723 88.895  1.00 44.82  ? 97  LEU   A CD1 1 
ATOM   600  C CD2 . LEU   A 1 97  ? 94.708  107.807 90.184  1.00 44.82  ? 97  LEU   A CD2 1 
ATOM   601  N N   . GLY   A 1 98  ? 93.951  103.699 93.459  1.00 49.65  ? 98  GLY   A N   1 
ATOM   602  C CA  . GLY   A 1 98  ? 93.561  103.361 94.815  1.00 49.65  ? 98  GLY   A CA  1 
ATOM   603  C C   . GLY   A 1 98  ? 94.734  103.410 95.770  1.00 49.65  ? 98  GLY   A C   1 
ATOM   604  O O   . GLY   A 1 98  ? 94.678  104.090 96.795  1.00 49.65  ? 98  GLY   A O   1 
ATOM   605  N N   . GLY   A 1 99  ? 95.843  102.767 95.393  1.00 49.35  ? 99  GLY   A N   1 
ATOM   606  C CA  . GLY   A 1 99  ? 97.036  102.811 96.221  1.00 49.35  ? 99  GLY   A CA  1 
ATOM   607  C C   . GLY   A 1 99  ? 97.588  104.210 96.411  1.00 49.35  ? 99  GLY   A C   1 
ATOM   608  O O   . GLY   A 1 99  ? 98.117  104.532 97.476  1.00 49.35  ? 99  GLY   A O   1 
ATOM   609  N N   . LEU   A 1 100 ? 97.473  105.060 95.389  1.00 49.37  ? 100 LEU   A N   1 
ATOM   610  C CA  . LEU   A 1 100 ? 98.002  106.415 95.507  1.00 49.37  ? 100 LEU   A CA  1 
ATOM   611  C C   . LEU   A 1 100 ? 97.126  107.298 96.389  1.00 49.37  ? 100 LEU   A C   1 
ATOM   612  O O   . LEU   A 1 100 ? 97.645  108.063 97.209  1.00 49.37  ? 100 LEU   A O   1 
ATOM   613  C CB  . LEU   A 1 100 ? 98.161  107.044 94.124  1.00 49.37  ? 100 LEU   A CB  1 
ATOM   614  C CG  . LEU   A 1 100 ? 99.478  106.779 93.397  1.00 49.37  ? 100 LEU   A CG  1 
ATOM   615  C CD1 . LEU   A 1 100 ? 99.313  106.985 91.902  1.00 49.37  ? 100 LEU   A CD1 1 
ATOM   616  C CD2 . LEU   A 1 100 ? 100.578 107.670 93.946  1.00 49.37  ? 100 LEU   A CD2 1 
ATOM   617  N N   . PHE   A 1 101 ? 95.802  107.217 96.243  1.00 51.66  ? 101 PHE   A N   1 
ATOM   618  C CA  . PHE   A 1 101 ? 94.937  108.253 96.794  1.00 51.66  ? 101 PHE   A CA  1 
ATOM   619  C C   . PHE   A 1 101 ? 93.886  107.776 97.787  1.00 51.66  ? 101 PHE   A C   1 
ATOM   620  O O   . PHE   A 1 101 ? 93.459  108.577 98.617  1.00 51.66  ? 101 PHE   A O   1 
ATOM   621  C CB  . PHE   A 1 101 ? 94.223  109.004 95.659  1.00 51.66  ? 101 PHE   A CB  1 
ATOM   622  C CG  . PHE   A 1 101 ? 95.154  109.751 94.749  1.00 51.66  ? 101 PHE   A CG  1 
ATOM   623  C CD1 . PHE   A 1 101 ? 95.967  110.755 95.245  1.00 51.66  ? 101 PHE   A CD1 1 
ATOM   624  C CD2 . PHE   A 1 101 ? 95.215  109.451 93.400  1.00 51.66  ? 101 PHE   A CD2 1 
ATOM   625  C CE1 . PHE   A 1 101 ? 96.825  111.444 94.414  1.00 51.66  ? 101 PHE   A CE1 1 
ATOM   626  C CE2 . PHE   A 1 101 ? 96.073  110.138 92.563  1.00 51.66  ? 101 PHE   A CE2 1 
ATOM   627  C CZ  . PHE   A 1 101 ? 96.878  111.136 93.071  1.00 51.66  ? 101 PHE   A CZ  1 
ATOM   628  N N   . PHE   A 1 102 ? 93.433  106.523 97.722  1.00 56.91  ? 102 PHE   A N   1 
ATOM   629  C CA  . PHE   A 1 102 ? 92.328  106.076 98.558  1.00 56.91  ? 102 PHE   A CA  1 
ATOM   630  C C   . PHE   A 1 102 ? 92.749  105.158 99.693  1.00 56.91  ? 102 PHE   A C   1 
ATOM   631  O O   . PHE   A 1 102 ? 92.055  105.105 100.708 1.00 56.91  ? 102 PHE   A O   1 
ATOM   632  C CB  . PHE   A 1 102 ? 91.277  105.353 97.706  1.00 56.91  ? 102 PHE   A CB  1 
ATOM   633  C CG  . PHE   A 1 102 ? 90.563  106.248 96.735  1.00 56.91  ? 102 PHE   A CG  1 
ATOM   634  C CD1 . PHE   A 1 102 ? 89.427  106.938 97.115  1.00 56.91  ? 102 PHE   A CD1 1 
ATOM   635  C CD2 . PHE   A 1 102 ? 91.030  106.401 95.441  1.00 56.91  ? 102 PHE   A CD2 1 
ATOM   636  C CE1 . PHE   A 1 102 ? 88.770  107.762 96.226  1.00 56.91  ? 102 PHE   A CE1 1 
ATOM   637  C CE2 . PHE   A 1 102 ? 90.377  107.225 94.547  1.00 56.91  ? 102 PHE   A CE2 1 
ATOM   638  C CZ  . PHE   A 1 102 ? 89.246  107.905 94.940  1.00 56.91  ? 102 PHE   A CZ  1 
ATOM   639  N N   . ALA   A 1 103 ? 93.863  104.436 99.546  1.00 62.11  ? 103 ALA   A N   1 
ATOM   640  C CA  . ALA   A 1 103 ? 94.283  103.494 100.579 1.00 62.11  ? 103 ALA   A CA  1 
ATOM   641  C C   . ALA   A 1 103 ? 94.661  104.205 101.873 1.00 62.11  ? 103 ALA   A C   1 
ATOM   642  O O   . ALA   A 1 103 ? 94.337  103.728 102.966 1.00 62.11  ? 103 ALA   A O   1 
ATOM   643  C CB  . ALA   A 1 103 ? 95.451  102.650 100.073 1.00 62.11  ? 103 ALA   A CB  1 
ATOM   644  N N   . LYS   A 1 104 ? 95.360  105.339 101.770 1.00 69.98  ? 104 LYS   A N   1 
ATOM   645  C CA  . LYS   A 1 104 ? 95.760  106.067 102.975 1.00 69.98  ? 104 LYS   A CA  1 
ATOM   646  C C   . LYS   A 1 104 ? 94.581  106.667 103.743 1.00 69.98  ? 104 LYS   A C   1 
ATOM   647  O O   . LYS   A 1 104 ? 94.531  106.490 104.974 1.00 69.98  ? 104 LYS   A O   1 
ATOM   648  C CB  . LYS   A 1 104 ? 96.815  107.119 102.616 1.00 69.98  ? 104 LYS   A CB  1 
ATOM   649  C CG  . LYS   A 1 104 ? 97.357  107.898 103.799 1.00 69.98  ? 104 LYS   A CG  1 
ATOM   650  C CD  . LYS   A 1 104 ? 98.411  108.895 103.349 1.00 69.98  ? 104 LYS   A CD  1 
ATOM   651  C CE  . LYS   A 1 104 ? 99.000  109.652 104.526 1.00 69.98  ? 104 LYS   A CE  1 
ATOM   652  N NZ  . LYS   A 1 104 ? 100.034 110.628 104.088 1.00 69.98  ? 104 LYS   A NZ  1 
ATOM   653  N N   . PRO   A 1 105 ? 93.627  107.388 103.125 1.00 69.95  ? 105 PRO   A N   1 
ATOM   654  C CA  . PRO   A 1 105 ? 92.520  107.934 103.933 1.00 69.95  ? 105 PRO   A CA  1 
ATOM   655  C C   . PRO   A 1 105 ? 91.591  106.879 104.512 1.00 69.95  ? 105 PRO   A C   1 
ATOM   656  O O   . PRO   A 1 105 ? 91.043  107.095 105.600 1.00 69.95  ? 105 PRO   A O   1 
ATOM   657  C CB  . PRO   A 1 105 ? 91.780  108.853 102.950 1.00 69.95  ? 105 PRO   A CB  1 
ATOM   658  C CG  . PRO   A 1 105 ? 92.762  109.144 101.887 1.00 69.95  ? 105 PRO   A CG  1 
ATOM   659  C CD  . PRO   A 1 105 ? 93.537  107.883 101.739 1.00 69.95  ? 105 PRO   A CD  1 
ATOM   660  N N   . MET   A 1 106 ? 91.380  105.756 103.820 1.00 73.53  ? 106 MET   A N   1 
ATOM   661  C CA  . MET   A 1 106 ? 90.568  104.684 104.390 1.00 73.53  ? 106 MET   A CA  1 
ATOM   662  C C   . MET   A 1 106 ? 91.236  104.066 105.611 1.00 73.53  ? 106 MET   A C   1 
ATOM   663  O O   . MET   A 1 106 ? 90.570  103.790 106.615 1.00 73.53  ? 106 MET   A O   1 
ATOM   664  C CB  . MET   A 1 106 ? 90.289  103.614 103.337 1.00 73.53  ? 106 MET   A CB  1 
ATOM   665  C CG  . MET   A 1 106 ? 89.424  104.081 102.187 1.00 73.53  ? 106 MET   A CG  1 
ATOM   666  S SD  . MET   A 1 106 ? 87.785  104.616 102.697 1.00 73.53  ? 106 MET   A SD  1 
ATOM   667  C CE  . MET   A 1 106 ? 87.060  103.053 103.184 1.00 73.53  ? 106 MET   A CE  1 
ATOM   668  N N   . ARG   A 1 107 ? 92.550  103.845 105.547 1.00 75.67  ? 107 ARG   A N   1 
ATOM   669  C CA  . ARG   A 1 107 ? 93.254  103.272 106.686 1.00 75.67  ? 107 ARG   A CA  1 
ATOM   670  C C   . ARG   A 1 107 ? 93.469  104.285 107.801 1.00 75.67  ? 107 ARG   A C   1 
ATOM   671  O O   . ARG   A 1 107 ? 93.711  103.884 108.944 1.00 75.67  ? 107 ARG   A O   1 
ATOM   672  C CB  . ARG   A 1 107 ? 94.599  102.697 106.245 1.00 75.67  ? 107 ARG   A CB  1 
ATOM   673  C CG  . ARG   A 1 107 ? 94.528  101.265 105.751 1.00 75.67  ? 107 ARG   A CG  1 
ATOM   674  C CD  . ARG   A 1 107 ? 95.916  100.672 105.602 1.00 75.67  ? 107 ARG   A CD  1 
ATOM   675  N NE  . ARG   A 1 107 ? 96.717  100.892 106.799 1.00 75.67  ? 107 ARG   A NE  1 
ATOM   676  C CZ  . ARG   A 1 107 ? 96.656  100.137 107.888 1.00 75.67  ? 107 ARG   A CZ  1 
ATOM   677  N NH1 . ARG   A 1 107 ? 95.859  99.084  107.955 1.00 75.67  ? 107 ARG   A NH1 1 
ATOM   678  N NH2 . ARG   A 1 107 ? 97.413  100.448 108.936 1.00 75.67  ? 107 ARG   A NH2 1 
ATOM   679  N N   . SER   A 1 108 ? 93.402  105.584 107.492 1.00 80.42  ? 108 SER   A N   1 
ATOM   680  C CA  . SER   A 1 108 ? 93.599  106.604 108.518 1.00 80.42  ? 108 SER   A CA  1 
ATOM   681  C C   . SER   A 1 108 ? 92.493  106.567 109.567 1.00 80.42  ? 108 SER   A C   1 
ATOM   682  O O   . SER   A 1 108 ? 92.763  106.691 110.768 1.00 80.42  ? 108 SER   A O   1 
ATOM   683  C CB  . SER   A 1 108 ? 93.677  107.987 107.872 1.00 80.42  ? 108 SER   A CB  1 
ATOM   684  O OG  . SER   A 1 108 ? 93.941  108.987 108.840 1.00 80.42  ? 108 SER   A OG  1 
ATOM   685  N N   . LYS   A 1 109 ? 91.246  106.397 109.137 1.00 80.81  ? 109 LYS   A N   1 
ATOM   686  C CA  . LYS   A 1 109 ? 90.106  106.412 110.045 1.00 80.81  ? 109 LYS   A CA  1 
ATOM   687  C C   . LYS   A 1 109 ? 89.720  105.028 110.551 1.00 80.81  ? 109 LYS   A C   1 
ATOM   688  O O   . LYS   A 1 109 ? 88.784  104.918 111.349 1.00 80.81  ? 109 LYS   A O   1 
ATOM   689  C CB  . LYS   A 1 109 ? 88.903  107.073 109.366 1.00 80.81  ? 109 LYS   A CB  1 
ATOM   690  C CG  . LYS   A 1 109 ? 89.091  108.562 109.115 1.00 80.81  ? 109 LYS   A CG  1 
ATOM   691  C CD  . LYS   A 1 109 ? 87.865  109.183 108.469 1.00 80.81  ? 109 LYS   A CD  1 
ATOM   692  C CE  . LYS   A 1 109 ? 88.077  110.664 108.203 1.00 80.81  ? 109 LYS   A CE  1 
ATOM   693  N NZ  . LYS   A 1 109 ? 86.890  111.291 107.558 1.00 80.81  ? 109 LYS   A NZ  1 
ATOM   694  N N   . GLY   A 1 110 ? 90.415  103.979 110.116 1.00 80.70  ? 110 GLY   A N   1 
ATOM   695  C CA  . GLY   A 1 110 ? 90.194  102.642 110.636 1.00 80.70  ? 110 GLY   A CA  1 
ATOM   696  C C   . GLY   A 1 110 ? 88.836  102.036 110.344 1.00 80.70  ? 110 GLY   A C   1 
ATOM   697  O O   . GLY   A 1 110 ? 88.199  101.474 111.240 1.00 80.70  ? 110 GLY   A O   1 
ATOM   698  N N   . TYR   A 1 111 ? 88.379  102.146 109.101 1.00 79.25  ? 111 TYR   A N   1 
ATOM   699  C CA  . TYR   A 1 111 ? 87.126  101.519 108.706 1.00 79.25  ? 111 TYR   A CA  1 
ATOM   700  C C   . TYR   A 1 111 ? 87.269  100.001 108.673 1.00 79.25  ? 111 TYR   A C   1 
ATOM   701  O O   . TYR   A 1 111 ? 88.375  99.459  108.613 1.00 79.25  ? 111 TYR   A O   1 
ATOM   702  C CB  . TYR   A 1 111 ? 86.679  102.034 107.338 1.00 79.25  ? 111 TYR   A CB  1 
ATOM   703  C CG  . TYR   A 1 111 ? 86.280  103.492 107.331 1.00 79.25  ? 111 TYR   A CG  1 
ATOM   704  C CD1 . TYR   A 1 111 ? 85.207  103.941 108.090 1.00 79.25  ? 111 TYR   A CD1 1 
ATOM   705  C CD2 . TYR   A 1 111 ? 86.974  104.419 106.565 1.00 79.25  ? 111 TYR   A CD2 1 
ATOM   706  C CE1 . TYR   A 1 111 ? 84.837  105.272 108.086 1.00 79.25  ? 111 TYR   A CE1 1 
ATOM   707  C CE2 . TYR   A 1 111 ? 86.610  105.753 106.555 1.00 79.25  ? 111 TYR   A CE2 1 
ATOM   708  C CZ  . TYR   A 1 111 ? 85.541  106.173 107.317 1.00 79.25  ? 111 TYR   A CZ  1 
ATOM   709  O OH  . TYR   A 1 111 ? 85.176  107.498 107.311 1.00 79.25  ? 111 TYR   A OH  1 
ATOM   710  N N   . VAL   A 1 112 ? 86.135  99.313  108.751 1.00 80.54  ? 112 VAL   A N   1 
ATOM   711  C CA  . VAL   A 1 112 ? 86.119  97.857  108.636 1.00 80.54  ? 112 VAL   A CA  1 
ATOM   712  C C   . VAL   A 1 112 ? 85.743  97.416  107.227 1.00 80.54  ? 112 VAL   A C   1 
ATOM   713  O O   . VAL   A 1 112 ? 86.450  96.619  106.604 1.00 80.54  ? 112 VAL   A O   1 
ATOM   714  C CB  . VAL   A 1 112 ? 85.169  97.250  109.691 1.00 80.54  ? 112 VAL   A CB  1 
ATOM   715  C CG1 . VAL   A 1 112 ? 85.009  95.755  109.468 1.00 80.54  ? 112 VAL   A CG1 1 
ATOM   716  C CG2 . VAL   A 1 112 ? 85.684  97.530  111.093 1.00 80.54  ? 112 VAL   A CG2 1 
ATOM   717  N N   . THR   A 1 113 ? 84.634  97.925  106.697 1.00 80.04  ? 113 THR   A N   1 
ATOM   718  C CA  . THR   A 1 113 ? 84.164  97.578  105.363 1.00 80.04  ? 113 THR   A CA  1 
ATOM   719  C C   . THR   A 1 113 ? 84.016  98.838  104.519 1.00 80.04  ? 113 THR   A C   1 
ATOM   720  O O   . THR   A 1 113 ? 84.216  99.960  104.989 1.00 80.04  ? 113 THR   A O   1 
ATOM   721  C CB  . THR   A 1 113 ? 82.831  96.817  105.417 1.00 80.04  ? 113 THR   A CB  1 
ATOM   722  O OG1 . THR   A 1 113 ? 81.828  97.642  106.018 1.00 80.04  ? 113 THR   A OG1 1 
ATOM   723  C CG2 . THR   A 1 113 ? 82.976  95.536  106.224 1.00 80.04  ? 113 THR   A CG2 1 
ATOM   724  N N   . MET   A 1 114 ? 83.662  98.635  103.246 1.00 73.23  ? 114 MET   A N   1 
ATOM   725  C CA  . MET   A 1 114 ? 83.598  99.749  102.304 1.00 73.23  ? 114 MET   A CA  1 
ATOM   726  C C   . MET   A 1 114 ? 82.396  100.647 102.573 1.00 73.23  ? 114 MET   A C   1 
ATOM   727  O O   . MET   A 1 114 ? 82.483  101.864 102.381 1.00 73.23  ? 114 MET   A O   1 
ATOM   728  C CB  . MET   A 1 114 ? 83.590  99.208  100.869 1.00 73.23  ? 114 MET   A CB  1 
ATOM   729  C CG  . MET   A 1 114 ? 83.598  100.250 99.742  1.00 73.23  ? 114 MET   A CG  1 
ATOM   730  S SD  . MET   A 1 114 ? 82.020  100.996 99.278  1.00 73.23  ? 114 MET   A SD  1 
ATOM   731  C CE  . MET   A 1 114 ? 81.233  99.626  98.436  1.00 73.23  ? 114 MET   A CE  1 
ATOM   732  N N   . LEU   A 1 115 ? 81.274  100.078 103.019 1.00 77.36  ? 115 LEU   A N   1 
ATOM   733  C CA  . LEU   A 1 115 ? 80.087  100.876 103.303 1.00 77.36  ? 115 LEU   A CA  1 
ATOM   734  C C   . LEU   A 1 115 ? 80.153  101.607 104.636 1.00 77.36  ? 115 LEU   A C   1 
ATOM   735  O O   . LEU   A 1 115 ? 79.261  102.414 104.915 1.00 77.36  ? 115 LEU   A O   1 
ATOM   736  C CB  . LEU   A 1 115 ? 78.827  100.006 103.285 1.00 77.36  ? 115 LEU   A CB  1 
ATOM   737  C CG  . LEU   A 1 115 ? 78.069  99.868  101.963 1.00 77.36  ? 115 LEU   A CG  1 
ATOM   738  C CD1 . LEU   A 1 115 ? 78.772  98.919  101.023 1.00 77.36  ? 115 LEU   A CD1 1 
ATOM   739  C CD2 . LEU   A 1 115 ? 76.639  99.418  102.216 1.00 77.36  ? 115 LEU   A CD2 1 
ATOM   740  N N   . ASP   A 1 116 ? 81.165  101.341 105.461 1.00 79.32  ? 116 ASP   A N   1 
ATOM   741  C CA  . ASP   A 1 116 ? 81.244  101.988 106.769 1.00 79.32  ? 116 ASP   A CA  1 
ATOM   742  C C   . ASP   A 1 116 ? 81.341  103.513 106.721 1.00 79.32  ? 116 ASP   A C   1 
ATOM   743  O O   . ASP   A 1 116 ? 80.695  104.157 107.566 1.00 79.32  ? 116 ASP   A O   1 
ATOM   744  C CB  . ASP   A 1 116 ? 82.402  101.389 107.576 1.00 79.32  ? 116 ASP   A CB  1 
ATOM   745  C CG  . ASP   A 1 116 ? 82.136  99.960  107.989 1.00 79.32  ? 116 ASP   A CG  1 
ATOM   746  O OD1 . ASP   A 1 116 ? 80.954  99.601  108.169 1.00 79.32  ? 116 ASP   A OD1 1 
ATOM   747  O OD2 . ASP   A 1 116 ? 83.107  99.191  108.124 1.00 79.32  ? 116 ASP   A OD2 1 
ATOM   748  N N   . PRO   A 1 117 ? 82.122  104.151 105.831 1.00 75.23  ? 117 PRO   A N   1 
ATOM   749  C CA  . PRO   A 1 117 ? 82.001  105.617 105.718 1.00 75.23  ? 117 PRO   A CA  1 
ATOM   750  C C   . PRO   A 1 117 ? 80.602  106.075 105.348 1.00 75.23  ? 117 PRO   A C   1 
ATOM   751  O O   . PRO   A 1 117 ? 80.120  107.080 105.885 1.00 75.23  ? 117 PRO   A O   1 
ATOM   752  C CB  . PRO   A 1 117 ? 83.027  105.976 104.631 1.00 75.23  ? 117 PRO   A CB  1 
ATOM   753  C CG  . PRO   A 1 117 ? 83.357  104.695 103.953 1.00 75.23  ? 117 PRO   A CG  1 
ATOM   754  C CD  . PRO   A 1 117 ? 83.243  103.657 105.010 1.00 75.23  ? 117 PRO   A CD  1 
ATOM   755  N N   . PHE   A 1 118 ? 79.926  105.342 104.460 1.00 69.09  ? 118 PHE   A N   1 
ATOM   756  C CA  . PHE   A 1 118 ? 78.550  105.680 104.110 1.00 69.09  ? 118 PHE   A CA  1 
ATOM   757  C C   . PHE   A 1 118 ? 77.624  105.519 105.308 1.00 69.09  ? 118 PHE   A C   1 
ATOM   758  O O   . PHE   A 1 118 ? 76.759  106.369 105.550 1.00 69.09  ? 118 PHE   A O   1 
ATOM   759  C CB  . PHE   A 1 118 ? 78.079  104.810 102.946 1.00 69.09  ? 118 PHE   A CB  1 
ATOM   760  C CG  . PHE   A 1 118 ? 78.896  104.973 101.699 1.00 69.09  ? 118 PHE   A CG  1 
ATOM   761  C CD1 . PHE   A 1 118 ? 79.221  106.231 101.227 1.00 69.09  ? 118 PHE   A CD1 1 
ATOM   762  C CD2 . PHE   A 1 118 ? 79.338  103.865 100.998 1.00 69.09  ? 118 PHE   A CD2 1 
ATOM   763  C CE1 . PHE   A 1 118 ? 79.973  106.381 100.081 1.00 69.09  ? 118 PHE   A CE1 1 
ATOM   764  C CE2 . PHE   A 1 118 ? 80.090  104.009 99.849  1.00 69.09  ? 118 PHE   A CE2 1 
ATOM   765  C CZ  . PHE   A 1 118 ? 80.407  105.268 99.391  1.00 69.09  ? 118 PHE   A CZ  1 
ATOM   766  N N   . GLN   A 1 119 ? 77.804  104.441 106.078 1.00 80.15  ? 119 GLN   A N   1 
ATOM   767  C CA  . GLN   A 1 119 ? 76.987  104.219 107.268 1.00 80.15  ? 119 GLN   A CA  1 
ATOM   768  C C   . GLN   A 1 119 ? 77.201  105.317 108.303 1.00 80.15  ? 119 GLN   A C   1 
ATOM   769  O O   . GLN   A 1 119 ? 76.245  105.775 108.939 1.00 80.15  ? 119 GLN   A O   1 
ATOM   770  C CB  . GLN   A 1 119 ? 77.308  102.854 107.879 1.00 80.15  ? 119 GLN   A CB  1 
ATOM   771  C CG  . GLN   A 1 119 ? 76.946  101.655 107.016 1.00 80.15  ? 119 GLN   A CG  1 
ATOM   772  C CD  . GLN   A 1 119 ? 75.462  101.550 106.743 1.00 80.15  ? 119 GLN   A CD  1 
ATOM   773  O OE1 . GLN   A 1 119 ? 75.007  101.774 105.623 1.00 80.15  ? 119 GLN   A OE1 1 
ATOM   774  N NE2 . GLN   A 1 119 ? 74.697  101.196 107.768 1.00 80.15  ? 119 GLN   A NE2 1 
ATOM   775  N N   . GLN   A 1 120 ? 78.449  105.746 108.492 1.00 82.79  ? 120 GLN   A N   1 
ATOM   776  C CA  . GLN   A 1 120 ? 78.740  106.728 109.531 1.00 82.79  ? 120 GLN   A CA  1 
ATOM   777  C C   . GLN   A 1 120 ? 78.327  108.138 109.124 1.00 82.79  ? 120 GLN   A C   1 
ATOM   778  O O   . GLN   A 1 120 ? 77.864  108.913 109.968 1.00 82.79  ? 120 GLN   A O   1 
ATOM   779  C CB  . GLN   A 1 120 ? 80.226  106.688 109.889 1.00 82.79  ? 120 GLN   A CB  1 
ATOM   780  C CG  . GLN   A 1 120 ? 80.651  105.411 110.595 1.00 82.79  ? 120 GLN   A CG  1 
ATOM   781  C CD  . GLN   A 1 120 ? 82.139  105.361 110.865 1.00 82.79  ? 120 GLN   A CD  1 
ATOM   782  O OE1 . GLN   A 1 120 ? 82.881  106.267 110.485 1.00 82.79  ? 120 GLN   A OE1 1 
ATOM   783  N NE2 . GLN   A 1 120 ? 82.586  104.297 111.522 1.00 82.79  ? 120 GLN   A NE2 1 
ATOM   784  N N   . ILE   A 1 121 ? 78.480  108.497 107.852 1.00 77.89  ? 121 ILE   A N   1 
ATOM   785  C CA  . ILE   A 1 121 ? 78.169  109.857 107.418 1.00 77.89  ? 121 ILE   A CA  1 
ATOM   786  C C   . ILE   A 1 121 ? 76.702  110.004 107.036 1.00 77.89  ? 121 ILE   A C   1 
ATOM   787  O O   . ILE   A 1 121 ? 76.004  110.884 107.546 1.00 77.89  ? 121 ILE   A O   1 
ATOM   788  C CB  . ILE   A 1 121 ? 79.096  110.272 106.257 1.00 77.89  ? 121 ILE   A CB  1 
ATOM   789  C CG1 . ILE   A 1 121 ? 80.563  110.183 106.686 1.00 77.89  ? 121 ILE   A CG1 1 
ATOM   790  C CG2 . ILE   A 1 121 ? 78.757  111.675 105.784 1.00 77.89  ? 121 ILE   A CG2 1 
ATOM   791  C CD1 . ILE   A 1 121 ? 80.981  111.253 107.669 1.00 77.89  ? 121 ILE   A CD1 1 
ATOM   792  N N   . TYR   A 1 122 ? 76.204  109.157 106.137 1.00 73.01  ? 122 TYR   A N   1 
ATOM   793  C CA  . TYR   A 1 122 ? 74.854  109.301 105.612 1.00 73.01  ? 122 TYR   A CA  1 
ATOM   794  C C   . TYR   A 1 122 ? 73.806  108.545 106.419 1.00 73.01  ? 122 TYR   A C   1 
ATOM   795  O O   . TYR   A 1 122 ? 72.612  108.684 106.136 1.00 73.01  ? 122 TYR   A O   1 
ATOM   796  C CB  . TYR   A 1 122 ? 74.800  108.829 104.157 1.00 73.01  ? 122 TYR   A CB  1 
ATOM   797  C CG  . TYR   A 1 122 ? 75.734  109.561 103.225 1.00 73.01  ? 122 TYR   A CG  1 
ATOM   798  C CD1 . TYR   A 1 122 ? 75.899  110.935 103.314 1.00 73.01  ? 122 TYR   A CD1 1 
ATOM   799  C CD2 . TYR   A 1 122 ? 76.436  108.879 102.240 1.00 73.01  ? 122 TYR   A CD2 1 
ATOM   800  C CE1 . TYR   A 1 122 ? 76.749  111.608 102.459 1.00 73.01  ? 122 TYR   A CE1 1 
ATOM   801  C CE2 . TYR   A 1 122 ? 77.284  109.544 101.379 1.00 73.01  ? 122 TYR   A CE2 1 
ATOM   802  C CZ  . TYR   A 1 122 ? 77.437  110.908 101.494 1.00 73.01  ? 122 TYR   A CZ  1 
ATOM   803  O OH  . TYR   A 1 122 ? 78.281  111.577 100.641 1.00 73.01  ? 122 TYR   A OH  1 
ATOM   804  N N   . GLY   A 1 123 ? 74.211  107.757 107.408 1.00 78.60  ? 123 GLY   A N   1 
ATOM   805  C CA  . GLY   A 1 123 ? 73.272  106.935 108.141 1.00 78.60  ? 123 GLY   A CA  1 
ATOM   806  C C   . GLY   A 1 123 ? 73.110  105.558 107.530 1.00 78.60  ? 123 GLY   A C   1 
ATOM   807  O O   . GLY   A 1 123 ? 73.688  105.216 106.495 1.00 78.60  ? 123 GLY   A O   1 
ATOM   808  N N   . LYS   A 1 124 ? 72.295  104.743 108.201 1.00 84.90  ? 124 LYS   A N   1 
ATOM   809  C CA  . LYS   A 1 124 ? 72.099  103.366 107.763 1.00 84.90  ? 124 LYS   A CA  1 
ATOM   810  C C   . LYS   A 1 124 ? 71.183  103.262 106.549 1.00 84.90  ? 124 LYS   A C   1 
ATOM   811  O O   . LYS   A 1 124 ? 71.399  102.398 105.693 1.00 84.90  ? 124 LYS   A O   1 
ATOM   812  C CB  . LYS   A 1 124 ? 71.539  102.523 108.909 1.00 84.90  ? 124 LYS   A CB  1 
ATOM   813  C CG  . LYS   A 1 124 ? 72.477  102.391 110.097 1.00 84.90  ? 124 LYS   A CG  1 
ATOM   814  C CD  . LYS   A 1 124 ? 71.887  101.488 111.166 1.00 84.90  ? 124 LYS   A CD  1 
ATOM   815  C CE  . LYS   A 1 124 ? 70.709  102.152 111.857 1.00 84.90  ? 124 LYS   A CE  1 
ATOM   816  N NZ  . LYS   A 1 124 ? 71.127  103.347 112.639 1.00 84.90  ? 124 LYS   A NZ  1 
ATOM   817  N N   . ARG   A 1 125 ? 70.166  104.121 106.454 1.00 85.40  ? 125 ARG   A N   1 
ATOM   818  C CA  . ARG   A 1 125 ? 69.203  104.011 105.362 1.00 85.40  ? 125 ARG   A CA  1 
ATOM   819  C C   . ARG   A 1 125 ? 69.826  104.397 104.025 1.00 85.40  ? 125 ARG   A C   1 
ATOM   820  O O   . ARG   A 1 125 ? 69.681  103.676 103.030 1.00 85.40  ? 125 ARG   A O   1 
ATOM   821  C CB  . ARG   A 1 125 ? 67.978  104.877 105.655 1.00 85.40  ? 125 ARG   A CB  1 
ATOM   822  C CG  . ARG   A 1 125 ? 66.937  104.201 106.533 1.00 85.40  ? 125 ARG   A CG  1 
ATOM   823  C CD  . ARG   A 1 125 ? 65.733  105.102 106.757 1.00 85.40  ? 125 ARG   A CD  1 
ATOM   824  N NE  . ARG   A 1 125 ? 66.029  106.191 107.680 1.00 85.40  ? 125 ARG   A NE  1 
ATOM   825  C CZ  . ARG   A 1 125 ? 65.337  107.321 107.752 1.00 85.40  ? 125 ARG   A CZ  1 
ATOM   826  N NH1 . ARG   A 1 125 ? 64.298  107.546 106.965 1.00 85.40  ? 125 ARG   A NH1 1 
ATOM   827  N NH2 . ARG   A 1 125 ? 65.697  108.247 108.636 1.00 85.40  ? 125 ARG   A NH2 1 
ATOM   828  N N   . MET   A 1 126 ? 70.526  105.533 103.980 1.00 77.68  ? 126 MET   A N   1 
ATOM   829  C CA  . MET   A 1 126 ? 71.109  105.975 102.719 1.00 77.68  ? 126 MET   A CA  1 
ATOM   830  C C   . MET   A 1 126 ? 72.242  105.045 102.299 1.00 77.68  ? 126 MET   A C   1 
ATOM   831  O O   . MET   A 1 126 ? 72.445  104.807 101.104 1.00 77.68  ? 126 MET   A O   1 
ATOM   832  C CB  . MET   A 1 126 ? 71.598  107.418 102.850 1.00 77.68  ? 126 MET   A CB  1 
ATOM   833  C CG  . MET   A 1 126 ? 72.334  107.970 101.639 1.00 77.68  ? 126 MET   A CG  1 
ATOM   834  S SD  . MET   A 1 126 ? 71.293  107.893 100.165 1.00 77.68  ? 126 MET   A SD  1 
ATOM   835  C CE  . MET   A 1 126 ? 72.455  107.353 98.921  1.00 77.68  ? 126 MET   A CE  1 
ATOM   836  N N   . GLY   A 1 127 ? 72.965  104.484 103.272 1.00 76.39  ? 127 GLY   A N   1 
ATOM   837  C CA  . GLY   A 1 127 ? 73.905  103.419 102.965 1.00 76.39  ? 127 GLY   A CA  1 
ATOM   838  C C   . GLY   A 1 127 ? 73.222  102.175 102.428 1.00 76.39  ? 127 GLY   A C   1 
ATOM   839  O O   . GLY   A 1 127 ? 73.774  101.467 101.585 1.00 76.39  ? 127 GLY   A O   1 
ATOM   840  N N   . GLY   A 1 128 ? 72.010  101.891 102.911 1.00 76.50  ? 128 GLY   A N   1 
ATOM   841  C CA  . GLY   A 1 128 ? 71.245  100.789 102.350 1.00 76.50  ? 128 GLY   A CA  1 
ATOM   842  C C   . GLY   A 1 128 ? 70.862  101.023 100.901 1.00 76.50  ? 128 GLY   A C   1 
ATOM   843  O O   . GLY   A 1 128 ? 70.893  100.100 100.083 1.00 76.50  ? 128 GLY   A O   1 
ATOM   844  N N   . LEU   A 1 129 ? 70.482  102.259 100.568 1.00 72.39  ? 129 LEU   A N   1 
ATOM   845  C CA  . LEU   A 1 129 ? 70.260  102.604 99.162  1.00 72.39  ? 129 LEU   A CA  1 
ATOM   846  C C   . LEU   A 1 129 ? 71.547  102.509 98.348  1.00 72.39  ? 129 LEU   A C   1 
ATOM   847  O O   . LEU   A 1 129 ? 71.521  102.092 97.186  1.00 72.39  ? 129 LEU   A O   1 
ATOM   848  C CB  . LEU   A 1 129 ? 69.641  103.998 99.015  1.00 72.39  ? 129 LEU   A CB  1 
ATOM   849  C CG  . LEU   A 1 129 ? 68.145  104.257 99.246  1.00 72.39  ? 129 LEU   A CG  1 
ATOM   850  C CD1 . LEU   A 1 129 ? 67.680  104.090 100.674 1.00 72.39  ? 129 LEU   A CD1 1 
ATOM   851  C CD2 . LEU   A 1 129 ? 67.787  105.649 98.736  1.00 72.39  ? 129 LEU   A CD2 1 
ATOM   852  N N   . LEU   A 1 130 ? 72.680  102.904 98.933  1.00 69.61  ? 130 LEU   A N   1 
ATOM   853  C CA  . LEU   A 1 130 ? 73.962  102.777 98.242  1.00 69.61  ? 130 LEU   A CA  1 
ATOM   854  C C   . LEU   A 1 130 ? 74.384  101.327 98.057  1.00 69.61  ? 130 LEU   A C   1 
ATOM   855  O O   . LEU   A 1 130 ? 75.185  101.035 97.164  1.00 69.61  ? 130 LEU   A O   1 
ATOM   856  C CB  . LEU   A 1 130 ? 75.054  103.527 99.003  1.00 69.61  ? 130 LEU   A CB  1 
ATOM   857  C CG  . LEU   A 1 130 ? 75.216  105.010 98.681  1.00 69.61  ? 130 LEU   A CG  1 
ATOM   858  C CD1 . LEU   A 1 130 ? 75.906  105.732 99.822  1.00 69.61  ? 130 LEU   A CD1 1 
ATOM   859  C CD2 . LEU   A 1 130 ? 75.983  105.192 97.388  1.00 69.61  ? 130 LEU   A CD2 1 
ATOM   860  N N   . PHE   A 1 131 ? 73.887  100.423 98.900  1.00 72.01  ? 131 PHE   A N   1 
ATOM   861  C CA  . PHE   A 1 131 ? 74.239  99.012  98.786  1.00 72.01  ? 131 PHE   A CA  1 
ATOM   862  C C   . PHE   A 1 131 ? 73.685  98.389  97.508  1.00 72.01  ? 131 PHE   A C   1 
ATOM   863  O O   . PHE   A 1 131 ? 74.279  97.444  96.976  1.00 72.01  ? 131 PHE   A O   1 
ATOM   864  C CB  . PHE   A 1 131 ? 73.736  98.263  100.022 1.00 72.01  ? 131 PHE   A CB  1 
ATOM   865  C CG  . PHE   A 1 131 ? 73.729  96.770  99.876  1.00 72.01  ? 131 PHE   A CG  1 
ATOM   866  C CD1 . PHE   A 1 131 ? 74.916  96.058  99.844  1.00 72.01  ? 131 PHE   A CD1 1 
ATOM   867  C CD2 . PHE   A 1 131 ? 72.534  96.076  99.786  1.00 72.01  ? 131 PHE   A CD2 1 
ATOM   868  C CE1 . PHE   A 1 131 ? 74.912  94.683  99.714  1.00 72.01  ? 131 PHE   A CE1 1 
ATOM   869  C CE2 . PHE   A 1 131 ? 72.523  94.702  99.656  1.00 72.01  ? 131 PHE   A CE2 1 
ATOM   870  C CZ  . PHE   A 1 131 ? 73.714  94.006  99.621  1.00 72.01  ? 131 PHE   A CZ  1 
ATOM   871  N N   . ILE   A 1 132 ? 72.561  98.907  97.000  1.00 65.82  ? 132 ILE   A N   1 
ATOM   872  C CA  . ILE   A 1 132 ? 71.929  98.304  95.822  1.00 65.82  ? 132 ILE   A CA  1 
ATOM   873  C C   . ILE   A 1 132 ? 72.799  98.393  94.568  1.00 65.82  ? 132 ILE   A C   1 
ATOM   874  O O   . ILE   A 1 132 ? 72.914  97.380  93.858  1.00 65.82  ? 132 ILE   A O   1 
ATOM   875  C CB  . ILE   A 1 132 ? 70.520  98.888  95.621  1.00 65.82  ? 132 ILE   A CB  1 
ATOM   876  C CG1 . ILE   A 1 132 ? 69.743  98.869  96.938  1.00 65.82  ? 132 ILE   A CG1 1 
ATOM   877  C CG2 . ILE   A 1 132 ? 69.770  98.119  94.549  1.00 65.82  ? 132 ILE   A CG2 1 
ATOM   878  C CD1 . ILE   A 1 132 ? 68.419  99.591  96.874  1.00 65.82  ? 132 ILE   A CD1 1 
ATOM   879  N N   . PRO   A 1 133 ? 73.408  99.543  94.217  1.00 60.53  ? 133 PRO   A N   1 
ATOM   880  C CA  . PRO   A 1 133 ? 74.360  99.511  93.090  1.00 60.53  ? 133 PRO   A CA  1 
ATOM   881  C C   . PRO   A 1 133 ? 75.551  98.599  93.325  1.00 60.53  ? 133 PRO   A C   1 
ATOM   882  O O   . PRO   A 1 133 ? 76.018  97.949  92.383  1.00 60.53  ? 133 PRO   A O   1 
ATOM   883  C CB  . PRO   A 1 133 ? 74.790  100.977 92.949  1.00 60.53  ? 133 PRO   A CB  1 
ATOM   884  C CG  . PRO   A 1 133 ? 73.682  101.747 93.501  1.00 60.53  ? 133 PRO   A CG  1 
ATOM   885  C CD  . PRO   A 1 133 ? 73.146  100.935 94.633  1.00 60.53  ? 133 PRO   A CD  1 
ATOM   886  N N   . ALA   A 1 134 ? 76.049  98.524  94.562  1.00 60.64  ? 134 ALA   A N   1 
ATOM   887  C CA  . ALA   A 1 134 ? 77.161  97.627  94.861  1.00 60.64  ? 134 ALA   A CA  1 
ATOM   888  C C   . ALA   A 1 134 ? 76.753  96.168  94.704  1.00 60.64  ? 134 ALA   A C   1 
ATOM   889  O O   . ALA   A 1 134 ? 77.503  95.366  94.134  1.00 60.64  ? 134 ALA   A O   1 
ATOM   890  C CB  . ALA   A 1 134 ? 77.683  97.891  96.272  1.00 60.64  ? 134 ALA   A CB  1 
ATOM   891  N N   . LEU   A 1 135 ? 75.565  95.810  95.201  1.00 61.40  ? 135 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 135 ? 75.068  94.447  95.041  1.00 61.40  ? 135 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 135 ? 74.843  94.109  93.574  1.00 61.40  ? 135 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 135 ? 75.159  93.000  93.132  1.00 61.40  ? 135 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 135 ? 73.778  94.263  95.839  1.00 61.40  ? 135 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 135 ? 73.093  92.900  95.723  1.00 61.40  ? 135 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 135 ? 73.685  91.907  96.708  1.00 61.40  ? 135 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 135 ? 71.594  93.040  95.932  1.00 61.40  ? 135 LEU   A CD2 1 
ATOM   899  N N   . MET   A 1 136 ? 74.306  95.057  92.802  1.00 58.03  ? 136 MET   A N   1 
ATOM   900  C CA  . MET   A 1 136 ? 74.106  94.830  91.374  1.00 58.03  ? 136 MET   A CA  1 
ATOM   901  C C   . MET   A 1 136 ? 75.434  94.649  90.650  1.00 58.03  ? 136 MET   A C   1 
ATOM   902  O O   . MET   A 1 136 ? 75.553  93.795  89.764  1.00 58.03  ? 136 MET   A O   1 
ATOM   903  C CB  . MET   A 1 136 ? 73.314  95.987  90.768  1.00 58.03  ? 136 MET   A CB  1 
ATOM   904  C CG  . MET   A 1 136 ? 71.809  95.785  90.787  1.00 58.03  ? 136 MET   A CG  1 
ATOM   905  S SD  . MET   A 1 136 ? 70.910  97.170  90.066  1.00 58.03  ? 136 MET   A SD  1 
ATOM   906  C CE  . MET   A 1 136 ? 71.826  97.413  88.548  1.00 58.03  ? 136 MET   A CE  1 
ATOM   907  N N   . GLY   A 1 137 ? 76.445  95.441  91.012  1.00 53.03  ? 137 GLY   A N   1 
ATOM   908  C CA  . GLY   A 1 137 ? 77.755  95.280  90.402  1.00 53.03  ? 137 GLY   A CA  1 
ATOM   909  C C   . GLY   A 1 137 ? 78.400  93.949  90.735  1.00 53.03  ? 137 GLY   A C   1 
ATOM   910  O O   . GLY   A 1 137 ? 78.986  93.299  89.863  1.00 53.03  ? 137 GLY   A O   1 
ATOM   911  N N   . GLU   A 1 138 ? 78.301  93.523  91.998  1.00 58.04  ? 138 GLU   A N   1 
ATOM   912  C CA  . GLU   A 1 138 ? 78.812  92.207  92.373  1.00 58.04  ? 138 GLU   A CA  1 
ATOM   913  C C   . GLU   A 1 138 ? 78.056  91.096  91.657  1.00 58.04  ? 138 GLU   A C   1 
ATOM   914  O O   . GLU   A 1 138 ? 78.646  90.078  91.283  1.00 58.04  ? 138 GLU   A O   1 
ATOM   915  C CB  . GLU   A 1 138 ? 78.737  92.012  93.887  1.00 58.04  ? 138 GLU   A CB  1 
ATOM   916  C CG  . GLU   A 1 138 ? 79.569  92.993  94.688  1.00 58.04  ? 138 GLU   A CG  1 
ATOM   917  C CD  . GLU   A 1 138 ? 80.941  92.450  95.028  1.00 58.04  ? 138 GLU   A CD  1 
ATOM   918  O OE1 . GLU   A 1 138 ? 81.595  93.009  95.933  1.00 58.04  ? 138 GLU   A OE1 1 
ATOM   919  O OE2 . GLU   A 1 138 ? 81.367  91.464  94.391  1.00 58.04  ? 138 GLU   A OE2 1 
ATOM   920  N N   . MET   A 1 139 ? 76.751  91.279  91.447  1.00 55.19  ? 139 MET   A N   1 
ATOM   921  C CA  . MET   A 1 139 ? 75.963  90.275  90.740  1.00 55.19  ? 139 MET   A CA  1 
ATOM   922  C C   . MET   A 1 139 ? 76.357  90.192  89.270  1.00 55.19  ? 139 MET   A C   1 
ATOM   923  O O   . MET   A 1 139 ? 76.453  89.095  88.712  1.00 55.19  ? 139 MET   A O   1 
ATOM   924  C CB  . MET   A 1 139 ? 74.477  90.592  90.890  1.00 55.19  ? 139 MET   A CB  1 
ATOM   925  C CG  . MET   A 1 139 ? 73.543  89.558  90.305  1.00 55.19  ? 139 MET   A CG  1 
ATOM   926  S SD  . MET   A 1 139 ? 71.828  90.041  90.561  1.00 55.19  ? 139 MET   A SD  1 
ATOM   927  C CE  . MET   A 1 139 ? 71.670  89.771  92.325  1.00 55.19  ? 139 MET   A CE  1 
ATOM   928  N N   . PHE   A 1 140 ? 76.597  91.340  88.629  1.00 44.42  ? 140 PHE   A N   1 
ATOM   929  C CA  . PHE   A 1 140 ? 77.076  91.343  87.247  1.00 44.42  ? 140 PHE   A CA  1 
ATOM   930  C C   . PHE   A 1 140 ? 78.452  90.695  87.135  1.00 44.42  ? 140 PHE   A C   1 
ATOM   931  O O   . PHE   A 1 140 ? 78.713  89.921  86.204  1.00 44.42  ? 140 PHE   A O   1 
ATOM   932  C CB  . PHE   A 1 140 ? 77.123  92.774  86.710  1.00 44.42  ? 140 PHE   A CB  1 
ATOM   933  C CG  . PHE   A 1 140 ? 75.798  93.295  86.232  1.00 44.42  ? 140 PHE   A CG  1 
ATOM   934  C CD1 . PHE   A 1 140 ? 75.096  92.634  85.245  1.00 44.42  ? 140 PHE   A CD1 1 
ATOM   935  C CD2 . PHE   A 1 140 ? 75.264  94.456  86.761  1.00 44.42  ? 140 PHE   A CD2 1 
ATOM   936  C CE1 . PHE   A 1 140 ? 73.879  93.111  84.804  1.00 44.42  ? 140 PHE   A CE1 1 
ATOM   937  C CE2 . PHE   A 1 140 ? 74.048  94.938  86.326  1.00 44.42  ? 140 PHE   A CE2 1 
ATOM   938  C CZ  . PHE   A 1 140 ? 73.356  94.265  85.345  1.00 44.42  ? 140 PHE   A CZ  1 
ATOM   939  N N   . TRP   A 1 141 ? 79.346  91.003  88.079  1.00 43.70  ? 141 TRP   A N   1 
ATOM   940  C CA  . TRP   A 1 141 ? 80.680  90.411  88.077  1.00 43.70  ? 141 TRP   A CA  1 
ATOM   941  C C   . TRP   A 1 141 ? 80.621  88.901  88.285  1.00 43.70  ? 141 TRP   A C   1 
ATOM   942  O O   . TRP   A 1 141 ? 81.321  88.143  87.603  1.00 43.70  ? 141 TRP   A O   1 
ATOM   943  C CB  . TRP   A 1 141 ? 81.532  91.087  89.153  1.00 43.70  ? 141 TRP   A CB  1 
ATOM   944  C CG  . TRP   A 1 141 ? 82.954  90.601  89.303  1.00 43.70  ? 141 TRP   A CG  1 
ATOM   945  C CD1 . TRP   A 1 141 ? 83.585  90.308  90.476  1.00 43.70  ? 141 TRP   A CD1 1 
ATOM   946  C CD2 . TRP   A 1 141 ? 83.929  90.396  88.266  1.00 43.70  ? 141 TRP   A CD2 1 
ATOM   947  N NE1 . TRP   A 1 141 ? 84.876  89.914  90.238  1.00 43.70  ? 141 TRP   A NE1 1 
ATOM   948  C CE2 . TRP   A 1 141 ? 85.113  89.960  88.891  1.00 43.70  ? 141 TRP   A CE2 1 
ATOM   949  C CE3 . TRP   A 1 141 ? 83.914  90.528  86.874  1.00 43.70  ? 141 TRP   A CE3 1 
ATOM   950  C CZ2 . TRP   A 1 141 ? 86.267  89.656  88.175  1.00 43.70  ? 141 TRP   A CZ2 1 
ATOM   951  C CZ3 . TRP   A 1 141 ? 85.058  90.220  86.167  1.00 43.70  ? 141 TRP   A CZ3 1 
ATOM   952  C CH2 . TRP   A 1 141 ? 86.219  89.793  86.817  1.00 43.70  ? 141 TRP   A CH2 1 
ATOM   953  N N   . ALA   A 1 142 ? 79.774  88.444  89.211  1.00 42.80  ? 142 ALA   A N   1 
ATOM   954  C CA  . ALA   A 1 142 ? 79.608  87.013  89.431  1.00 42.80  ? 142 ALA   A CA  1 
ATOM   955  C C   . ALA   A 1 142 ? 78.965  86.330  88.235  1.00 42.80  ? 142 ALA   A C   1 
ATOM   956  O O   . ALA   A 1 142 ? 79.295  85.181  87.936  1.00 42.80  ? 142 ALA   A O   1 
ATOM   957  C CB  . ALA   A 1 142 ? 78.780  86.767  90.690  1.00 42.80  ? 142 ALA   A CB  1 
ATOM   958  N N   . ALA   A 1 143 ? 78.048  87.012  87.544  1.00 40.07  ? 143 ALA   A N   1 
ATOM   959  C CA  . ALA   A 1 143 ? 77.467  86.452  86.329  1.00 40.07  ? 143 ALA   A CA  1 
ATOM   960  C C   . ALA   A 1 143 ? 78.517  86.290  85.240  1.00 40.07  ? 143 ALA   A C   1 
ATOM   961  O O   . ALA   A 1 143 ? 78.531  85.279  84.531  1.00 40.07  ? 143 ALA   A O   1 
ATOM   962  C CB  . ALA   A 1 143 ? 76.320  87.335  85.840  1.00 40.07  ? 143 ALA   A CB  1 
ATOM   963  N N   . ALA   A 1 144 ? 79.406  87.276  85.093  1.00 39.69  ? 144 ALA   A N   1 
ATOM   964  C CA  . ALA   A 1 144 ? 80.497  87.153  84.128  1.00 39.69  ? 144 ALA   A CA  1 
ATOM   965  C C   . ALA   A 1 144 ? 81.437  86.009  84.494  1.00 39.69  ? 144 ALA   A C   1 
ATOM   966  O O   . ALA   A 1 144 ? 81.867  85.240  83.622  1.00 39.69  ? 144 ALA   A O   1 
ATOM   967  C CB  . ALA   A 1 144 ? 81.267  88.469  84.036  1.00 39.69  ? 144 ALA   A CB  1 
ATOM   968  N N   . ILE   A 1 145 ? 81.760  85.879  85.785  1.00 39.52  ? 145 ILE   A N   1 
ATOM   969  C CA  . ILE   A 1 145 ? 82.630  84.797  86.243  1.00 39.52  ? 145 ILE   A CA  1 
ATOM   970  C C   . ILE   A 1 145 ? 81.986  83.439  85.982  1.00 39.52  ? 145 ILE   A C   1 
ATOM   971  O O   . ILE   A 1 145 ? 82.643  82.506  85.504  1.00 39.52  ? 145 ILE   A O   1 
ATOM   972  C CB  . ILE   A 1 145 ? 82.971  84.986  87.733  1.00 39.52  ? 145 ILE   A CB  1 
ATOM   973  C CG1 . ILE   A 1 145 ? 83.906  86.178  87.923  1.00 39.52  ? 145 ILE   A CG1 1 
ATOM   974  C CG2 . ILE   A 1 145 ? 83.603  83.734  88.307  1.00 39.52  ? 145 ILE   A CG2 1 
ATOM   975  C CD1 . ILE   A 1 145 ? 84.230  86.465  89.367  1.00 39.52  ? 145 ILE   A CD1 1 
ATOM   976  N N   . PHE   A 1 146 ? 80.690  83.311  86.282  1.00 39.80  ? 146 PHE   A N   1 
ATOM   977  C CA  . PHE   A 1 146 ? 79.984  82.054  86.056  1.00 39.80  ? 146 PHE   A CA  1 
ATOM   978  C C   . PHE   A 1 146 ? 79.875  81.735  84.573  1.00 39.80  ? 146 PHE   A C   1 
ATOM   979  O O   . PHE   A 1 146 ? 79.964  80.568  84.183  1.00 39.80  ? 146 PHE   A O   1 
ATOM   980  C CB  . PHE   A 1 146 ? 78.596  82.104  86.687  1.00 39.80  ? 146 PHE   A CB  1 
ATOM   981  C CG  . PHE   A 1 146 ? 78.593  81.843  88.161  1.00 39.80  ? 146 PHE   A CG  1 
ATOM   982  C CD1 . PHE   A 1 146 ? 79.610  81.114  88.749  1.00 39.80  ? 146 PHE   A CD1 1 
ATOM   983  C CD2 . PHE   A 1 146 ? 77.569  82.318  88.958  1.00 39.80  ? 146 PHE   A CD2 1 
ATOM   984  C CE1 . PHE   A 1 146 ? 79.610  80.872  90.102  1.00 39.80  ? 146 PHE   A CE1 1 
ATOM   985  C CE2 . PHE   A 1 146 ? 77.563  82.078  90.312  1.00 39.80  ? 146 PHE   A CE2 1 
ATOM   986  C CZ  . PHE   A 1 146 ? 78.584  81.354  90.884  1.00 39.80  ? 146 PHE   A CZ  1 
ATOM   987  N N   . SER   A 1 147 ? 79.672  82.753  83.734  1.00 39.70  ? 147 SER   A N   1 
ATOM   988  C CA  . SER   A 1 147 ? 79.631  82.526  82.294  1.00 39.70  ? 147 SER   A CA  1 
ATOM   989  C C   . SER   A 1 147 ? 80.972  82.023  81.777  1.00 39.70  ? 147 SER   A C   1 
ATOM   990  O O   . SER   A 1 147 ? 81.022  81.074  80.986  1.00 39.70  ? 147 SER   A O   1 
ATOM   991  C CB  . SER   A 1 147 ? 79.222  83.809  81.575  1.00 39.70  ? 147 SER   A CB  1 
ATOM   992  O OG  . SER   A 1 147 ? 79.003  83.571  80.197  1.00 39.70  ? 147 SER   A OG  1 
ATOM   993  N N   . ALA   A 1 148 ? 82.072  82.628  82.234  1.00 38.33  ? 148 ALA   A N   1 
ATOM   994  C CA  . ALA   A 1 148 ? 83.395  82.172  81.813  1.00 38.33  ? 148 ALA   A CA  1 
ATOM   995  C C   . ALA   A 1 148 ? 83.685  80.758  82.309  1.00 38.33  ? 148 ALA   A C   1 
ATOM   996  O O   . ALA   A 1 148 ? 84.229  79.929  81.567  1.00 38.33  ? 148 ALA   A O   1 
ATOM   997  C CB  . ALA   A 1 148 ? 84.464  83.143  82.307  1.00 38.33  ? 148 ALA   A CB  1 
ATOM   998  N N   . LEU   A 1 149 ? 83.328  80.466  83.563  1.00 43.23  ? 149 LEU   A N   1 
ATOM   999  C CA  . LEU   A 1 149 ? 83.562  79.137  84.120  1.00 43.23  ? 149 LEU   A CA  1 
ATOM   1000 C C   . LEU   A 1 149 ? 82.739  78.078  83.397  1.00 43.23  ? 149 LEU   A C   1 
ATOM   1001 O O   . LEU   A 1 149 ? 83.248  76.994  83.081  1.00 43.23  ? 149 LEU   A O   1 
ATOM   1002 C CB  . LEU   A 1 149 ? 83.243  79.138  85.614  1.00 43.23  ? 149 LEU   A CB  1 
ATOM   1003 C CG  . LEU   A 1 149 ? 83.262  77.789  86.328  1.00 43.23  ? 149 LEU   A CG  1 
ATOM   1004 C CD1 . LEU   A 1 149 ? 84.632  77.141  86.218  1.00 43.23  ? 149 LEU   A CD1 1 
ATOM   1005 C CD2 . LEU   A 1 149 ? 82.855  77.957  87.782  1.00 43.23  ? 149 LEU   A CD2 1 
ATOM   1006 N N   . GLY   A 1 150 ? 81.467  78.372  83.128  1.00 40.39  ? 150 GLY   A N   1 
ATOM   1007 C CA  . GLY   A 1 150 ? 80.641  77.440  82.386  1.00 40.39  ? 150 GLY   A CA  1 
ATOM   1008 C C   . GLY   A 1 150 ? 81.129  77.239  80.968  1.00 40.39  ? 150 GLY   A C   1 
ATOM   1009 O O   . GLY   A 1 150 ? 81.066  76.130  80.439  1.00 40.39  ? 150 GLY   A O   1 
ATOM   1010 N N   . ALA   A 1 151 ? 81.637  78.302  80.339  1.00 42.25  ? 151 ALA   A N   1 
ATOM   1011 C CA  . ALA   A 1 151 ? 82.211  78.169  79.005  1.00 42.25  ? 151 ALA   A CA  1 
ATOM   1012 C C   . ALA   A 1 151 ? 83.427  77.256  79.016  1.00 42.25  ? 151 ALA   A C   1 
ATOM   1013 O O   . ALA   A 1 151 ? 83.555  76.369  78.163  1.00 42.25  ? 151 ALA   A O   1 
ATOM   1014 C CB  . ALA   A 1 151 ? 82.584  79.545  78.463  1.00 42.25  ? 151 ALA   A CB  1 
ATOM   1015 N N   . THR   A 1 152 ? 84.320  77.444  79.990  1.00 43.14  ? 152 THR   A N   1 
ATOM   1016 C CA  . THR   A 1 152 ? 85.520  76.617  80.062  1.00 43.14  ? 152 THR   A CA  1 
ATOM   1017 C C   . THR   A 1 152 ? 85.169  75.156  80.329  1.00 43.14  ? 152 THR   A C   1 
ATOM   1018 O O   . THR   A 1 152 ? 85.735  74.247  79.707  1.00 43.14  ? 152 THR   A O   1 
ATOM   1019 C CB  . THR   A 1 152 ? 86.456  77.154  81.143  1.00 43.14  ? 152 THR   A CB  1 
ATOM   1020 O OG1 . THR   A 1 152 ? 86.512  78.583  81.058  1.00 43.14  ? 152 THR   A OG1 1 
ATOM   1021 C CG2 . THR   A 1 152 ? 87.852  76.621  80.931  1.00 43.14  ? 152 THR   A CG2 1 
ATOM   1022 N N   . ILE   A 1 153 ? 84.215  74.913  81.232  1.00 44.83  ? 153 ILE   A N   1 
ATOM   1023 C CA  . ILE   A 1 153 ? 83.827  73.544  81.563  1.00 44.83  ? 153 ILE   A CA  1 
ATOM   1024 C C   . ILE   A 1 153 ? 83.105  72.886  80.389  1.00 44.83  ? 153 ILE   A C   1 
ATOM   1025 O O   . ILE   A 1 153 ? 83.343  71.711  80.073  1.00 44.83  ? 153 ILE   A O   1 
ATOM   1026 C CB  . ILE   A 1 153 ? 82.978  73.542  82.848  1.00 44.83  ? 153 ILE   A CB  1 
ATOM   1027 C CG1 . ILE   A 1 153 ? 83.856  73.882  84.052  1.00 44.83  ? 153 ILE   A CG1 1 
ATOM   1028 C CG2 . ILE   A 1 153 ? 82.318  72.201  83.071  1.00 44.83  ? 153 ILE   A CG2 1 
ATOM   1029 C CD1 . ILE   A 1 153 ? 83.129  73.843  85.370  1.00 44.83  ? 153 ILE   A CD1 1 
ATOM   1030 N N   . SER   A 1 154 ? 82.235  73.634  79.706  1.00 46.32  ? 154 SER   A N   1 
ATOM   1031 C CA  . SER   A 1 154 ? 81.541  73.106  78.540  1.00 46.32  ? 154 SER   A CA  1 
ATOM   1032 C C   . SER   A 1 154 ? 82.495  72.848  77.386  1.00 46.32  ? 154 SER   A C   1 
ATOM   1033 O O   . SER   A 1 154 ? 82.196  72.028  76.514  1.00 46.32  ? 154 SER   A O   1 
ATOM   1034 C CB  . SER   A 1 154 ? 80.440  74.069  78.102  1.00 46.32  ? 154 SER   A CB  1 
ATOM   1035 O OG  . SER   A 1 154 ? 79.999  73.773  76.790  1.00 46.32  ? 154 SER   A OG  1 
ATOM   1036 N N   . VAL   A 1 155 ? 83.622  73.555  77.336  1.00 46.20  ? 155 VAL   A N   1 
ATOM   1037 C CA  . VAL   A 1 155 ? 84.614  73.257  76.310  1.00 46.20  ? 155 VAL   A CA  1 
ATOM   1038 C C   . VAL   A 1 155 ? 85.412  72.007  76.673  1.00 46.20  ? 155 VAL   A C   1 
ATOM   1039 O O   . VAL   A 1 155 ? 85.648  71.142  75.820  1.00 46.20  ? 155 VAL   A O   1 
ATOM   1040 C CB  . VAL   A 1 155 ? 85.518  74.480  76.074  1.00 46.20  ? 155 VAL   A CB  1 
ATOM   1041 C CG1 . VAL   A 1 155 ? 86.775  74.085  75.333  1.00 46.20  ? 155 VAL   A CG1 1 
ATOM   1042 C CG2 . VAL   A 1 155 ? 84.765  75.525  75.272  1.00 46.20  ? 155 VAL   A CG2 1 
ATOM   1043 N N   . ILE   A 1 156 ? 85.830  71.878  77.939  1.00 53.40  ? 156 ILE   A N   1 
ATOM   1044 C CA  . ILE   A 1 156 ? 86.686  70.747  78.303  1.00 53.40  ? 156 ILE   A CA  1 
ATOM   1045 C C   . ILE   A 1 156 ? 85.909  69.433  78.270  1.00 53.40  ? 156 ILE   A C   1 
ATOM   1046 O O   . ILE   A 1 156 ? 86.454  68.392  77.886  1.00 53.40  ? 156 ILE   A O   1 
ATOM   1047 C CB  . ILE   A 1 156 ? 87.375  70.965  79.667  1.00 53.40  ? 156 ILE   A CB  1 
ATOM   1048 C CG1 . ILE   A 1 156 ? 86.378  71.091  80.813  1.00 53.40  ? 156 ILE   A CG1 1 
ATOM   1049 C CG2 . ILE   A 1 156 ? 88.222  72.195  79.646  1.00 53.40  ? 156 ILE   A CG2 1 
ATOM   1050 C CD1 . ILE   A 1 156 ? 87.024  71.064  82.181  1.00 53.40  ? 156 ILE   A CD1 1 
ATOM   1051 N N   . ILE   A 1 157 ? 84.631  69.448  78.662  1.00 59.45  ? 157 ILE   A N   1 
ATOM   1052 C CA  . ILE   A 1 157 ? 83.858  68.211  78.741  1.00 59.45  ? 157 ILE   A CA  1 
ATOM   1053 C C   . ILE   A 1 157 ? 82.966  68.006  77.516  1.00 59.45  ? 157 ILE   A C   1 
ATOM   1054 O O   . ILE   A 1 157 ? 82.499  66.880  77.276  1.00 59.45  ? 157 ILE   A O   1 
ATOM   1055 C CB  . ILE   A 1 157 ? 83.046  68.179  80.057  1.00 59.45  ? 157 ILE   A CB  1 
ATOM   1056 C CG1 . ILE   A 1 157 ? 83.968  68.442  81.243  1.00 59.45  ? 157 ILE   A CG1 1 
ATOM   1057 C CG2 . ILE   A 1 157 ? 82.429  66.828  80.326  1.00 59.45  ? 157 ILE   A CG2 1 
ATOM   1058 C CD1 . ILE   A 1 157 ? 83.241  68.738  82.526  1.00 59.45  ? 157 ILE   A CD1 1 
ATOM   1059 N N   . ASP   A 1 158 ? 82.785  69.071  76.735  1.00 62.37  ? 158 ASP   A N   1 
ATOM   1060 C CA  . ASP   A 1 158 ? 81.944  69.085  75.531  1.00 62.37  ? 158 ASP   A CA  1 
ATOM   1061 C C   . ASP   A 1 158 ? 80.473  68.759  75.847  1.00 62.37  ? 158 ASP   A C   1 
ATOM   1062 O O   . ASP   A 1 158 ? 79.888  67.818  75.313  1.00 62.37  ? 158 ASP   A O   1 
ATOM   1063 C CB  . ASP   A 1 158 ? 82.527  68.236  74.376  1.00 62.37  ? 158 ASP   A CB  1 
ATOM   1064 C CG  . ASP   A 1 158 ? 81.795  68.445  73.057  1.00 62.37  ? 158 ASP   A CG  1 
ATOM   1065 O OD1 . ASP   A 1 158 ? 80.605  68.823  73.078  1.00 62.37  ? 158 ASP   A OD1 1 
ATOM   1066 O OD2 . ASP   A 1 158 ? 82.413  68.224  71.993  1.00 62.37  ? 158 ASP   A OD2 1 
ATOM   1067 N N   . VAL   A 1 159 ? 79.905  69.562  76.743  1.00 58.01  ? 159 VAL   A N   1 
ATOM   1068 C CA  . VAL   A 1 159 ? 78.515  69.469  77.159  1.00 58.01  ? 159 VAL   A CA  1 
ATOM   1069 C C   . VAL   A 1 159 ? 77.822  70.772  76.776  1.00 58.01  ? 159 VAL   A C   1 
ATOM   1070 O O   . VAL   A 1 159 ? 78.451  71.723  76.312  1.00 58.01  ? 159 VAL   A O   1 
ATOM   1071 C CB  . VAL   A 1 159 ? 78.363  69.181  78.666  1.00 58.01  ? 159 VAL   A CB  1 
ATOM   1072 C CG1 . VAL   A 1 159 ? 79.008  67.851  79.024  1.00 58.01  ? 159 VAL   A CG1 1 
ATOM   1073 C CG2 . VAL   A 1 159 ? 78.979  70.298  79.485  1.00 58.01  ? 159 VAL   A CG2 1 
ATOM   1074 N N   . ASP   A 1 160 ? 76.503  70.791  76.952  1.00 60.66  ? 160 ASP   A N   1 
ATOM   1075 C CA  . ASP   A 1 160 ? 75.728  71.986  76.647  1.00 60.66  ? 160 ASP   A CA  1 
ATOM   1076 C C   . ASP   A 1 160 ? 76.119  73.137  77.566  1.00 60.66  ? 160 ASP   A C   1 
ATOM   1077 O O   . ASP   A 1 160 ? 76.473  72.934  78.730  1.00 60.66  ? 160 ASP   A O   1 
ATOM   1078 C CB  . ASP   A 1 160 ? 74.234  71.698  76.766  1.00 60.66  ? 160 ASP   A CB  1 
ATOM   1079 C CG  . ASP   A 1 160 ? 73.388  72.742  76.068  1.00 60.66  ? 160 ASP   A CG  1 
ATOM   1080 O OD1 . ASP   A 1 160 ? 73.842  73.285  75.038  1.00 60.66  ? 160 ASP   A OD1 1 
ATOM   1081 O OD2 . ASP   A 1 160 ? 72.273  73.026  76.551  1.00 60.66  ? 160 ASP   A OD2 1 
ATOM   1082 N N   . MET   A 1 161 ? 76.067  74.353  77.015  1.00 55.24  ? 161 MET   A N   1 
ATOM   1083 C CA  . MET   A 1 161 ? 76.479  75.550  77.745  1.00 55.24  ? 161 MET   A CA  1 
ATOM   1084 C C   . MET   A 1 161 ? 75.627  75.784  78.988  1.00 55.24  ? 161 MET   A C   1 
ATOM   1085 O O   . MET   A 1 161 ? 76.154  76.110  80.060  1.00 55.24  ? 161 MET   A O   1 
ATOM   1086 C CB  . MET   A 1 161 ? 76.400  76.754  76.807  1.00 55.24  ? 161 MET   A CB  1 
ATOM   1087 C CG  . MET   A 1 161 ? 76.931  78.064  77.348  1.00 55.24  ? 161 MET   A CG  1 
ATOM   1088 S SD  . MET   A 1 161 ? 78.699  78.097  77.662  1.00 55.24  ? 161 MET   A SD  1 
ATOM   1089 C CE  . MET   A 1 161 ? 78.764  79.407  78.876  1.00 55.24  ? 161 MET   A CE  1 
ATOM   1090 N N   . HIS   A 1 162 ? 74.309  75.611  78.867  1.00 57.85  ? 162 HIS   A N   1 
ATOM   1091 C CA  . HIS   A 1 162 ? 73.404  75.959  79.959  1.00 57.85  ? 162 HIS   A CA  1 
ATOM   1092 C C   . HIS   A 1 162 ? 73.538  74.991  81.129  1.00 57.85  ? 162 HIS   A C   1 
ATOM   1093 O O   . HIS   A 1 162 ? 73.621  75.413  82.290  1.00 57.85  ? 162 HIS   A O   1 
ATOM   1094 C CB  . HIS   A 1 162 ? 71.965  75.995  79.446  1.00 57.85  ? 162 HIS   A CB  1 
ATOM   1095 C CG  . HIS   A 1 162 ? 71.776  76.859  78.238  1.00 57.85  ? 162 HIS   A CG  1 
ATOM   1096 N ND1 . HIS   A 1 162 ? 71.492  78.204  78.323  1.00 57.85  ? 162 HIS   A ND1 1 
ATOM   1097 C CD2 . HIS   A 1 162 ? 71.836  76.570  76.916  1.00 57.85  ? 162 HIS   A CD2 1 
ATOM   1098 C CE1 . HIS   A 1 162 ? 71.381  78.707  77.106  1.00 57.85  ? 162 HIS   A CE1 1 
ATOM   1099 N NE2 . HIS   A 1 162 ? 71.586  77.736  76.235  1.00 57.85  ? 162 HIS   A NE2 1 
ATOM   1100 N N   . ILE   A 1 163 ? 73.553  73.687  80.842  1.00 53.28  ? 163 ILE   A N   1 
ATOM   1101 C CA  . ILE   A 1 163 ? 73.702  72.692  81.900  1.00 53.28  ? 163 ILE   A CA  1 
ATOM   1102 C C   . ILE   A 1 163 ? 75.070  72.819  82.558  1.00 53.28  ? 163 ILE   A C   1 
ATOM   1103 O O   . ILE   A 1 163 ? 75.200  72.679  83.778  1.00 53.28  ? 163 ILE   A O   1 
ATOM   1104 C CB  . ILE   A 1 163 ? 73.449  71.267  81.359  1.00 53.28  ? 163 ILE   A CB  1 
ATOM   1105 C CG1 . ILE   A 1 163 ? 72.002  71.096  80.868  1.00 53.28  ? 163 ILE   A CG1 1 
ATOM   1106 C CG2 . ILE   A 1 163 ? 73.760  70.213  82.411  1.00 53.28  ? 163 ILE   A CG2 1 
ATOM   1107 C CD1 . ILE   A 1 163 ? 71.746  71.443  79.416  1.00 53.28  ? 163 ILE   A CD1 1 
ATOM   1108 N N   . SER   A 1 164 ? 76.106  73.112  81.767  1.00 47.67  ? 164 SER   A N   1 
ATOM   1109 C CA  . SER   A 1 164 ? 77.437  73.321  82.331  1.00 47.67  ? 164 SER   A CA  1 
ATOM   1110 C C   . SER   A 1 164 ? 77.464  74.516  83.276  1.00 47.67  ? 164 SER   A C   1 
ATOM   1111 O O   . SER   A 1 164 ? 78.044  74.438  84.366  1.00 47.67  ? 164 SER   A O   1 
ATOM   1112 C CB  . SER   A 1 164 ? 78.456  73.510  81.212  1.00 47.67  ? 164 SER   A CB  1 
ATOM   1113 O OG  . SER   A 1 164 ? 79.757  73.668  81.738  1.00 47.67  ? 164 SER   A OG  1 
ATOM   1114 N N   . VAL   A 1 165 ? 76.833  75.626  82.880  1.00 47.59  ? 165 VAL   A N   1 
ATOM   1115 C CA  . VAL   A 1 165 ? 76.781  76.806  83.741  1.00 47.59  ? 165 VAL   A CA  1 
ATOM   1116 C C   . VAL   A 1 165 ? 76.028  76.498  85.028  1.00 47.59  ? 165 VAL   A C   1 
ATOM   1117 O O   . VAL   A 1 165 ? 76.478  76.852  86.126  1.00 47.59  ? 165 VAL   A O   1 
ATOM   1118 C CB  . VAL   A 1 165 ? 76.151  77.991  82.985  1.00 47.59  ? 165 VAL   A CB  1 
ATOM   1119 C CG1 . VAL   A 1 165 ? 75.660  79.054  83.953  1.00 47.59  ? 165 VAL   A CG1 1 
ATOM   1120 C CG2 . VAL   A 1 165 ? 77.147  78.588  82.027  1.00 47.59  ? 165 VAL   A CG2 1 
ATOM   1121 N N   . ILE   A 1 166 ? 74.884  75.817  84.915  1.00 50.73  ? 166 ILE   A N   1 
ATOM   1122 C CA  . ILE   A 1 166 ? 74.076  75.507  86.093  1.00 50.73  ? 166 ILE   A CA  1 
ATOM   1123 C C   . ILE   A 1 166 ? 74.833  74.584  87.042  1.00 50.73  ? 166 ILE   A C   1 
ATOM   1124 O O   . ILE   A 1 166 ? 74.860  74.812  88.257  1.00 50.73  ? 166 ILE   A O   1 
ATOM   1125 C CB  . ILE   A 1 166 ? 72.723  74.906  85.668  1.00 50.73  ? 166 ILE   A CB  1 
ATOM   1126 C CG1 . ILE   A 1 166 ? 71.866  75.964  84.974  1.00 50.73  ? 166 ILE   A CG1 1 
ATOM   1127 C CG2 . ILE   A 1 166 ? 71.980  74.341  86.867  1.00 50.73  ? 166 ILE   A CG2 1 
ATOM   1128 C CD1 . ILE   A 1 166 ? 70.534  75.445  84.486  1.00 50.73  ? 166 ILE   A CD1 1 
ATOM   1129 N N   . ILE   A 1 167 ? 75.482  73.547  86.503  1.00 50.81  ? 167 ILE   A N   1 
ATOM   1130 C CA  . ILE   A 1 167 ? 76.220  72.605  87.341  1.00 50.81  ? 167 ILE   A CA  1 
ATOM   1131 C C   . ILE   A 1 167 ? 77.412  73.283  88.008  1.00 50.81  ? 167 ILE   A C   1 
ATOM   1132 O O   . ILE   A 1 167 ? 77.655  73.085  89.203  1.00 50.81  ? 167 ILE   A O   1 
ATOM   1133 C CB  . ILE   A 1 167 ? 76.646  71.373  86.519  1.00 50.81  ? 167 ILE   A CB  1 
ATOM   1134 C CG1 . ILE   A 1 167 ? 75.424  70.537  86.136  1.00 50.81  ? 167 ILE   A CG1 1 
ATOM   1135 C CG2 . ILE   A 1 167 ? 77.634  70.517  87.290  1.00 50.81  ? 167 ILE   A CG2 1 
ATOM   1136 C CD1 . ILE   A 1 167 ? 74.637  70.027  87.321  1.00 50.81  ? 167 ILE   A CD1 1 
ATOM   1137 N N   . SER   A 1 168 ? 78.173  74.093  87.262  1.00 49.67  ? 168 SER   A N   1 
ATOM   1138 C CA  . SER   A 1 168 ? 79.329  74.764  87.852  1.00 49.67  ? 168 SER   A CA  1 
ATOM   1139 C C   . SER   A 1 168 ? 78.908  75.748  88.937  1.00 49.67  ? 168 SER   A C   1 
ATOM   1140 O O   . SER   A 1 168 ? 79.542  75.823  89.999  1.00 49.67  ? 168 SER   A O   1 
ATOM   1141 C CB  . SER   A 1 168 ? 80.135  75.476  86.768  1.00 49.67  ? 168 SER   A CB  1 
ATOM   1142 O OG  . SER   A 1 168 ? 79.393  76.538  86.198  1.00 49.67  ? 168 SER   A OG  1 
ATOM   1143 N N   . ALA   A 1 169 ? 77.832  76.503  88.696  1.00 52.38  ? 169 ALA   A N   1 
ATOM   1144 C CA  . ALA   A 1 169 ? 77.329  77.422  89.710  1.00 52.38  ? 169 ALA   A CA  1 
ATOM   1145 C C   . ALA   A 1 169 ? 76.827  76.670  90.935  1.00 52.38  ? 169 ALA   A C   1 
ATOM   1146 O O   . ALA   A 1 169 ? 77.015  77.125  92.068  1.00 52.38  ? 169 ALA   A O   1 
ATOM   1147 C CB  . ALA   A 1 169 ? 76.220  78.292  89.125  1.00 52.38  ? 169 ALA   A CB  1 
ATOM   1148 N N   . LEU   A 1 170 ? 76.193  75.513  90.727  1.00 56.83  ? 170 LEU   A N   1 
ATOM   1149 C CA  . LEU   A 1 170 ? 75.718  74.708  91.847  1.00 56.83  ? 170 LEU   A CA  1 
ATOM   1150 C C   . LEU   A 1 170 ? 76.879  74.173  92.679  1.00 56.83  ? 170 LEU   A C   1 
ATOM   1151 O O   . LEU   A 1 170 ? 76.822  74.190  93.914  1.00 56.83  ? 170 LEU   A O   1 
ATOM   1152 C CB  . LEU   A 1 170 ? 74.851  73.564  91.325  1.00 56.83  ? 170 LEU   A CB  1 
ATOM   1153 C CG  . LEU   A 1 170 ? 74.101  72.711  92.344  1.00 56.83  ? 170 LEU   A CG  1 
ATOM   1154 C CD1 . LEU   A 1 170 ? 73.109  73.567  93.108  1.00 56.83  ? 170 LEU   A CD1 1 
ATOM   1155 C CD2 . LEU   A 1 170 ? 73.395  71.559  91.652  1.00 56.83  ? 170 LEU   A CD2 1 
ATOM   1156 N N   . ILE   A 1 171 ? 77.940  73.698  92.022  1.00 55.55  ? 171 ILE   A N   1 
ATOM   1157 C CA  . ILE   A 1 171 ? 79.107  73.202  92.751  1.00 55.55  ? 171 ILE   A CA  1 
ATOM   1158 C C   . ILE   A 1 171 ? 79.776  74.329  93.527  1.00 55.55  ? 171 ILE   A C   1 
ATOM   1159 O O   . ILE   A 1 171 ? 80.175  74.147  94.683  1.00 55.55  ? 171 ILE   A O   1 
ATOM   1160 C CB  . ILE   A 1 171 ? 80.094  72.501  91.797  1.00 55.55  ? 171 ILE   A CB  1 
ATOM   1161 C CG1 . ILE   A 1 171 ? 79.418  71.323  91.096  1.00 55.55  ? 171 ILE   A CG1 1 
ATOM   1162 C CG2 . ILE   A 1 171 ? 81.327  72.029  92.546  1.00 55.55  ? 171 ILE   A CG2 1 
ATOM   1163 C CD1 . ILE   A 1 171 ? 78.927  70.251  92.041  1.00 55.55  ? 171 ILE   A CD1 1 
ATOM   1164 N N   . ALA   A 1 172 ? 79.905  75.510  92.914  1.00 59.73  ? 172 ALA   A N   1 
ATOM   1165 C CA  . ALA   A 1 172 ? 80.484  76.646  93.628  1.00 59.73  ? 172 ALA   A CA  1 
ATOM   1166 C C   . ALA   A 1 172 ? 79.621  77.058  94.817  1.00 59.73  ? 172 ALA   A C   1 
ATOM   1167 O O   . ALA   A 1 172 ? 80.144  77.379  95.893  1.00 59.73  ? 172 ALA   A O   1 
ATOM   1168 C CB  . ALA   A 1 172 ? 80.680  77.822  92.673  1.00 59.73  ? 172 ALA   A CB  1 
ATOM   1169 N N   . THR   A 1 173 ? 78.296  77.041  94.646  1.00 65.09  ? 173 THR   A N   1 
ATOM   1170 C CA  . THR   A 1 173 ? 77.393  77.413  95.731  1.00 65.09  ? 173 THR   A CA  1 
ATOM   1171 C C   . THR   A 1 173 ? 77.471  76.426  96.891  1.00 65.09  ? 173 THR   A C   1 
ATOM   1172 O O   . THR   A 1 173 ? 77.495  76.837  98.055  1.00 65.09  ? 173 THR   A O   1 
ATOM   1173 C CB  . THR   A 1 173 ? 75.961  77.511  95.205  1.00 65.09  ? 173 THR   A CB  1 
ATOM   1174 O OG1 . THR   A 1 173 ? 75.918  78.437  94.112  1.00 65.09  ? 173 THR   A OG1 1 
ATOM   1175 C CG2 . THR   A 1 173 ? 75.021  77.992  96.297  1.00 65.09  ? 173 THR   A CG2 1 
ATOM   1176 N N   . LEU   A 1 174 ? 77.514  75.123  96.600  1.00 67.16  ? 174 LEU   A N   1 
ATOM   1177 C CA  . LEU   A 1 174 ? 77.645  74.142  97.676  1.00 67.16  ? 174 LEU   A CA  1 
ATOM   1178 C C   . LEU   A 1 174 ? 79.030  74.160  98.313  1.00 67.16  ? 174 LEU   A C   1 
ATOM   1179 O O   . LEU   A 1 174 ? 79.155  73.877  99.510  1.00 67.16  ? 174 LEU   A O   1 
ATOM   1180 C CB  . LEU   A 1 174 ? 77.302  72.733  97.184  1.00 67.16  ? 174 LEU   A CB  1 
ATOM   1181 C CG  . LEU   A 1 174 ? 75.835  72.280  97.136  1.00 67.16  ? 174 LEU   A CG  1 
ATOM   1182 C CD1 . LEU   A 1 174 ? 75.276  72.246  98.549  1.00 67.16  ? 174 LEU   A CD1 1 
ATOM   1183 C CD2 . LEU   A 1 174 ? 74.944  73.137  96.260  1.00 67.16  ? 174 LEU   A CD2 1 
ATOM   1184 N N   . TYR   A 1 175 ? 80.077  74.471  97.544  1.00 70.33  ? 175 TYR   A N   1 
ATOM   1185 C CA  . TYR   A 1 175 ? 81.404  74.611  98.137  1.00 70.33  ? 175 TYR   A CA  1 
ATOM   1186 C C   . TYR   A 1 175 ? 81.460  75.799  99.087  1.00 70.33  ? 175 TYR   A C   1 
ATOM   1187 O O   . TYR   A 1 175 ? 82.091  75.725  100.148 1.00 70.33  ? 175 TYR   A O   1 
ATOM   1188 C CB  . TYR   A 1 175 ? 82.460  74.747  97.042  1.00 70.33  ? 175 TYR   A CB  1 
ATOM   1189 C CG  . TYR   A 1 175 ? 83.869  74.857  97.573  1.00 70.33  ? 175 TYR   A CG  1 
ATOM   1190 C CD1 . TYR   A 1 175 ? 84.538  73.741  98.057  1.00 70.33  ? 175 TYR   A CD1 1 
ATOM   1191 C CD2 . TYR   A 1 175 ? 84.531  76.078  97.592  1.00 70.33  ? 175 TYR   A CD2 1 
ATOM   1192 C CE1 . TYR   A 1 175 ? 85.827  73.837  98.545  1.00 70.33  ? 175 TYR   A CE1 1 
ATOM   1193 C CE2 . TYR   A 1 175 ? 85.819  76.184  98.078  1.00 70.33  ? 175 TYR   A CE2 1 
ATOM   1194 C CZ  . TYR   A 1 175 ? 86.462  75.061  98.553  1.00 70.33  ? 175 TYR   A CZ  1 
ATOM   1195 O OH  . TYR   A 1 175 ? 87.746  75.164  99.038  1.00 70.33  ? 175 TYR   A OH  1 
ATOM   1196 N N   . THR   A 1 176 ? 80.818  76.909  98.717  1.00 72.86  ? 176 THR   A N   1 
ATOM   1197 C CA  . THR   A 1 176 ? 80.695  78.035  99.636  1.00 72.86  ? 176 THR   A CA  1 
ATOM   1198 C C   . THR   A 1 176 ? 79.836  77.673  100.843 1.00 72.86  ? 176 THR   A C   1 
ATOM   1199 O O   . THR   A 1 176 ? 80.141  78.072  101.974 1.00 72.86  ? 176 THR   A O   1 
ATOM   1200 C CB  . THR   A 1 176 ? 80.110  79.242  98.901  1.00 72.86  ? 176 THR   A CB  1 
ATOM   1201 O OG1 . THR   A 1 176 ? 80.979  79.612  97.823  1.00 72.86  ? 176 THR   A OG1 1 
ATOM   1202 C CG2 . THR   A 1 176 ? 79.938  80.422  99.842  1.00 72.86  ? 176 THR   A CG2 1 
ATOM   1203 N N   . LEU   A 1 177 ? 78.767  76.905  100.618 1.00 76.17  ? 177 LEU   A N   1 
ATOM   1204 C CA  . LEU   A 1 177 ? 77.797  76.609  101.668 1.00 76.17  ? 177 LEU   A CA  1 
ATOM   1205 C C   . LEU   A 1 177 ? 78.417  75.793  102.796 1.00 76.17  ? 177 LEU   A C   1 
ATOM   1206 O O   . LEU   A 1 177 ? 78.191  76.085  103.976 1.00 76.17  ? 177 LEU   A O   1 
ATOM   1207 C CB  . LEU   A 1 177 ? 76.604  75.870  101.063 1.00 76.17  ? 177 LEU   A CB  1 
ATOM   1208 C CG  . LEU   A 1 177 ? 75.425  75.553  101.978 1.00 76.17  ? 177 LEU   A CG  1 
ATOM   1209 C CD1 . LEU   A 1 177 ? 74.805  76.841  102.468 1.00 76.17  ? 177 LEU   A CD1 1 
ATOM   1210 C CD2 . LEU   A 1 177 ? 74.394  74.704  101.252 1.00 76.17  ? 177 LEU   A CD2 1 
ATOM   1211 N N   . VAL   A 1 178 ? 79.198  74.772  102.457 1.00 76.09  ? 178 VAL   A N   1 
ATOM   1212 C CA  . VAL   A 1 178 ? 79.878  73.933  103.436 1.00 76.09  ? 178 VAL   A CA  1 
ATOM   1213 C C   . VAL   A 1 178 ? 81.368  73.985  103.137 1.00 76.09  ? 178 VAL   A C   1 
ATOM   1214 O O   . VAL   A 1 178 ? 81.810  73.523  102.078 1.00 76.09  ? 178 VAL   A O   1 
ATOM   1215 C CB  . VAL   A 1 178 ? 79.364  72.486  103.409 1.00 76.09  ? 178 VAL   A CB  1 
ATOM   1216 C CG1 . VAL   A 1 178 ? 80.152  71.627  104.384 1.00 76.09  ? 178 VAL   A CG1 1 
ATOM   1217 C CG2 . VAL   A 1 178 ? 77.879  72.443  103.735 1.00 76.09  ? 178 VAL   A CG2 1 
ATOM   1218 N N   . GLY   A 1 179 ? 82.139  74.537  104.068 1.00 76.55  ? 179 GLY   A N   1 
ATOM   1219 C CA  . GLY   A 1 179 ? 83.573  74.663  103.891 1.00 76.55  ? 179 GLY   A CA  1 
ATOM   1220 C C   . GLY   A 1 179 ? 83.973  75.914  103.134 1.00 76.55  ? 179 GLY   A C   1 
ATOM   1221 O O   . GLY   A 1 179 ? 83.392  76.981  103.330 1.00 76.55  ? 179 GLY   A O   1 
ATOM   1222 N N   . SER   A 1 183 ? 91.668  74.583  106.965 1.00 91.90  ? 183 SER   A N   1 
ATOM   1223 C CA  . SER   A 1 183 ? 92.441  74.447  105.736 1.00 91.90  ? 183 SER   A CA  1 
ATOM   1224 C C   . SER   A 1 183 ? 92.206  75.636  104.811 1.00 91.90  ? 183 SER   A C   1 
ATOM   1225 O O   . SER   A 1 183 ? 91.760  76.695  105.261 1.00 91.90  ? 183 SER   A O   1 
ATOM   1226 C CB  . SER   A 1 183 ? 92.087  73.141  105.020 1.00 91.90  ? 183 SER   A CB  1 
ATOM   1227 O OG  . SER   A 1 183 ? 90.708  73.090  104.697 1.00 91.90  ? 183 SER   A OG  1 
ATOM   1228 N N   . VAL   A 1 184 ? 92.512  75.436  103.525 1.00 89.49  ? 184 VAL   A N   1 
ATOM   1229 C CA  . VAL   A 1 184 ? 92.360  76.434  102.468 1.00 89.49  ? 184 VAL   A CA  1 
ATOM   1230 C C   . VAL   A 1 184 ? 93.215  77.641  102.861 1.00 89.49  ? 184 VAL   A C   1 
ATOM   1231 O O   . VAL   A 1 184 ? 92.705  78.698  103.250 1.00 89.49  ? 184 VAL   A O   1 
ATOM   1232 C CB  . VAL   A 1 184 ? 90.871  76.777  102.223 1.00 89.49  ? 184 VAL   A CB  1 
ATOM   1233 C CG1 . VAL   A 1 184 ? 90.681  77.872  101.156 1.00 89.49  ? 184 VAL   A CG1 1 
ATOM   1234 C CG2 . VAL   A 1 184 ? 90.097  75.523  101.844 1.00 89.49  ? 184 VAL   A CG2 1 
ATOM   1235 N N   . ALA   A 1 185 ? 94.530  77.444  102.870 1.00 87.80  ? 185 ALA   A N   1 
ATOM   1236 C CA  . ALA   A 1 185 ? 95.491  78.500  103.159 1.00 87.80  ? 185 ALA   A CA  1 
ATOM   1237 C C   . ALA   A 1 185 ? 96.382  78.705  101.944 1.00 87.80  ? 185 ALA   A C   1 
ATOM   1238 O O   . ALA   A 1 185 ? 96.876  77.730  101.366 1.00 87.80  ? 185 ALA   A O   1 
ATOM   1239 C CB  . ALA   A 1 185 ? 96.335  78.161  104.390 1.00 87.80  ? 185 ALA   A CB  1 
ATOM   1240 N N   . TYR   A 1 186 ? 96.576  79.971  101.561 1.00 82.47  ? 186 TYR   A N   1 
ATOM   1241 C CA  . TYR   A 1 186 ? 97.375  80.359  100.393 1.00 82.47  ? 186 TYR   A CA  1 
ATOM   1242 C C   . TYR   A 1 186 ? 96.865  79.710  99.109  1.00 82.47  ? 186 TYR   A C   1 
ATOM   1243 O O   . TYR   A 1 186 ? 97.649  79.367  98.222  1.00 82.47  ? 186 TYR   A O   1 
ATOM   1244 C CB  . TYR   A 1 186 ? 98.865  80.042  100.586 1.00 82.47  ? 186 TYR   A CB  1 
ATOM   1245 C CG  . TYR   A 1 186 ? 99.548  80.797  101.707 1.00 82.47  ? 186 TYR   A CG  1 
ATOM   1246 C CD1 . TYR   A 1 186 ? 98.949  81.900  102.304 1.00 82.47  ? 186 TYR   A CD1 1 
ATOM   1247 C CD2 . TYR   A 1 186 ? 100.798 80.404  102.166 1.00 82.47  ? 186 TYR   A CD2 1 
ATOM   1248 C CE1 . TYR   A 1 186 ? 99.575  82.587  103.325 1.00 82.47  ? 186 TYR   A CE1 1 
ATOM   1249 C CE2 . TYR   A 1 186 ? 101.431 81.085  103.186 1.00 82.47  ? 186 TYR   A CE2 1 
ATOM   1250 C CZ  . TYR   A 1 186 ? 100.814 82.175  103.762 1.00 82.47  ? 186 TYR   A CZ  1 
ATOM   1251 O OH  . TYR   A 1 186 ? 101.440 82.858  104.779 1.00 82.47  ? 186 TYR   A OH  1 
ATOM   1252 N N   . THR   A 1 187 ? 95.548  79.534  98.998  1.00 75.74  ? 187 THR   A N   1 
ATOM   1253 C CA  . THR   A 1 187 ? 94.982  78.940  97.794  1.00 75.74  ? 187 THR   A CA  1 
ATOM   1254 C C   . THR   A 1 187 ? 94.958  79.916  96.627  1.00 75.74  ? 187 THR   A C   1 
ATOM   1255 O O   . THR   A 1 187 ? 95.066  79.489  95.473  1.00 75.74  ? 187 THR   A O   1 
ATOM   1256 C CB  . THR   A 1 187 ? 93.569  78.423  98.068  1.00 75.74  ? 187 THR   A CB  1 
ATOM   1257 O OG1 . THR   A 1 187 ? 92.799  79.445  98.712  1.00 75.74  ? 187 THR   A OG1 1 
ATOM   1258 C CG2 . THR   A 1 187 ? 93.618  77.192  98.954  1.00 75.74  ? 187 THR   A CG2 1 
ATOM   1259 N N   . ASP   A 1 188 ? 94.816  81.217  96.904  1.00 72.93  ? 188 ASP   A N   1 
ATOM   1260 C CA  . ASP   A 1 188 ? 94.777  82.211  95.834  1.00 72.93  ? 188 ASP   A CA  1 
ATOM   1261 C C   . ASP   A 1 188 ? 96.093  82.259  95.069  1.00 72.93  ? 188 ASP   A C   1 
ATOM   1262 O O   . ASP   A 1 188 ? 96.101  82.429  93.843  1.00 72.93  ? 188 ASP   A O   1 
ATOM   1263 C CB  . ASP   A 1 188 ? 94.443  83.587  96.409  1.00 72.93  ? 188 ASP   A CB  1 
ATOM   1264 C CG  . ASP   A 1 188 ? 93.010  83.685  96.890  1.00 72.93  ? 188 ASP   A CG  1 
ATOM   1265 O OD1 . ASP   A 1 188 ? 92.158  82.930  96.379  1.00 72.93  ? 188 ASP   A OD1 1 
ATOM   1266 O OD2 . ASP   A 1 188 ? 92.735  84.520  97.777  1.00 72.93  ? 188 ASP   A OD2 1 
ATOM   1267 N N   . VAL   A 1 189 ? 97.215  82.115  95.778  1.00 66.59  ? 189 VAL   A N   1 
ATOM   1268 C CA  . VAL   A 1 189 ? 98.521  82.092  95.126  1.00 66.59  ? 189 VAL   A CA  1 
ATOM   1269 C C   . VAL   A 1 189 ? 98.622  80.903  94.179  1.00 66.59  ? 189 VAL   A C   1 
ATOM   1270 O O   . VAL   A 1 189 ? 99.102  81.032  93.046  1.00 66.59  ? 189 VAL   A O   1 
ATOM   1271 C CB  . VAL   A 1 189 ? 99.641  82.073  96.183  1.00 66.59  ? 189 VAL   A CB  1 
ATOM   1272 C CG1 . VAL   A 1 189 ? 101.002 81.913  95.524  1.00 66.59  ? 189 VAL   A CG1 1 
ATOM   1273 C CG2 . VAL   A 1 189 ? 99.595  83.336  97.025  1.00 66.59  ? 189 VAL   A CG2 1 
ATOM   1274 N N   . VAL   A 1 190 ? 98.151  79.734  94.618  1.00 63.77  ? 190 VAL   A N   1 
ATOM   1275 C CA  . VAL   A 1 190 ? 98.203  78.542  93.775  1.00 63.77  ? 190 VAL   A CA  1 
ATOM   1276 C C   . VAL   A 1 190 ? 97.275  78.689  92.574  1.00 63.77  ? 190 VAL   A C   1 
ATOM   1277 O O   . VAL   A 1 190 ? 97.610  78.260  91.465  1.00 63.77  ? 190 VAL   A O   1 
ATOM   1278 C CB  . VAL   A 1 190 ? 97.869  77.288  94.602  1.00 63.77  ? 190 VAL   A CB  1 
ATOM   1279 C CG1 . VAL   A 1 190 ? 98.133  76.030  93.792  1.00 63.77  ? 190 VAL   A CG1 1 
ATOM   1280 C CG2 . VAL   A 1 190 ? 98.680  77.273  95.883  1.00 63.77  ? 190 VAL   A CG2 1 
ATOM   1281 N N   . GLN   A 1 191 ? 96.100  79.294  92.772  1.00 64.21  ? 191 GLN   A N   1 
ATOM   1282 C CA  . GLN   A 1 191 ? 95.175  79.514  91.661  1.00 64.21  ? 191 GLN   A CA  1 
ATOM   1283 C C   . GLN   A 1 191 ? 95.781  80.442  90.616  1.00 64.21  ? 191 GLN   A C   1 
ATOM   1284 O O   . GLN   A 1 191 ? 95.712  80.172  89.409  1.00 64.21  ? 191 GLN   A O   1 
ATOM   1285 C CB  . GLN   A 1 191 ? 93.862  80.097  92.181  1.00 64.21  ? 191 GLN   A CB  1 
ATOM   1286 C CG  . GLN   A 1 191 ? 93.041  79.160  93.038  1.00 64.21  ? 191 GLN   A CG  1 
ATOM   1287 C CD  . GLN   A 1 191 ? 92.114  79.915  93.969  1.00 64.21  ? 191 GLN   A CD  1 
ATOM   1288 O OE1 . GLN   A 1 191 ? 92.060  81.144  93.941  1.00 64.21  ? 191 GLN   A OE1 1 
ATOM   1289 N NE2 . GLN   A 1 191 ? 91.400  79.187  94.817  1.00 64.21  ? 191 GLN   A NE2 1 
ATOM   1290 N N   . LEU   A 1 192 ? 96.385  81.545  91.067  1.00 55.66  ? 192 LEU   A N   1 
ATOM   1291 C CA  . LEU   A 1 192 ? 96.999  82.487  90.139  1.00 55.66  ? 192 LEU   A CA  1 
ATOM   1292 C C   . LEU   A 1 192 ? 98.194  81.862  89.430  1.00 55.66  ? 192 LEU   A C   1 
ATOM   1293 O O   . LEU   A 1 192 ? 98.401  82.092  88.233  1.00 55.66  ? 192 LEU   A O   1 
ATOM   1294 C CB  . LEU   A 1 192 ? 97.411  83.758  90.880  1.00 55.66  ? 192 LEU   A CB  1 
ATOM   1295 C CG  . LEU   A 1 192 ? 98.035  84.866  90.035  1.00 55.66  ? 192 LEU   A CG  1 
ATOM   1296 C CD1 . LEU   A 1 192 ? 97.054  85.337  88.978  1.00 55.66  ? 192 LEU   A CD1 1 
ATOM   1297 C CD2 . LEU   A 1 192 ? 98.471  86.023  90.913  1.00 55.66  ? 192 LEU   A CD2 1 
ATOM   1298 N N   . PHE   A 1 193 ? 98.981  81.058  90.149  1.00 56.70  ? 193 PHE   A N   1 
ATOM   1299 C CA  . PHE   A 1 193 ? 100.107 80.367  89.531  1.00 56.70  ? 193 PHE   A CA  1 
ATOM   1300 C C   . PHE   A 1 193 ? 99.635  79.364  88.486  1.00 56.70  ? 193 PHE   A C   1 
ATOM   1301 O O   . PHE   A 1 193 ? 100.244 79.241  87.418  1.00 56.70  ? 193 PHE   A O   1 
ATOM   1302 C CB  . PHE   A 1 193 ? 100.941 79.673  90.606  1.00 56.70  ? 193 PHE   A CB  1 
ATOM   1303 C CG  . PHE   A 1 193 ? 102.249 79.137  90.109  1.00 56.70  ? 193 PHE   A CG  1 
ATOM   1304 C CD1 . PHE   A 1 193 ? 103.285 79.995  89.785  1.00 56.70  ? 193 PHE   A CD1 1 
ATOM   1305 C CD2 . PHE   A 1 193 ? 102.447 77.773  89.975  1.00 56.70  ? 193 PHE   A CD2 1 
ATOM   1306 C CE1 . PHE   A 1 193 ? 104.494 79.503  89.329  1.00 56.70  ? 193 PHE   A CE1 1 
ATOM   1307 C CE2 . PHE   A 1 193 ? 103.653 77.274  89.520  1.00 56.70  ? 193 PHE   A CE2 1 
ATOM   1308 C CZ  . PHE   A 1 193 ? 104.678 78.141  89.197  1.00 56.70  ? 193 PHE   A CZ  1 
ATOM   1309 N N   . CYS   A 1 194 ? 98.552  78.636  88.775  1.00 58.70  ? 194 CYS   A N   1 
ATOM   1310 C CA  . CYS   A 1 194 ? 98.012  77.688  87.806  1.00 58.70  ? 194 CYS   A CA  1 
ATOM   1311 C C   . CYS   A 1 194 ? 97.492  78.399  86.564  1.00 58.70  ? 194 CYS   A C   1 
ATOM   1312 O O   . CYS   A 1 194 ? 97.724  77.939  85.440  1.00 58.70  ? 194 CYS   A O   1 
ATOM   1313 C CB  . CYS   A 1 194 ? 96.906  76.849  88.446  1.00 58.70  ? 194 CYS   A CB  1 
ATOM   1314 S SG  . CYS   A 1 194 ? 97.491  75.605  89.616  1.00 58.70  ? 194 CYS   A SG  1 
ATOM   1315 N N   . ILE   A 1 195 ? 96.795  79.526  86.746  1.00 50.34  ? 195 ILE   A N   1 
ATOM   1316 C CA  . ILE   A 1 195 ? 96.308  80.298  85.602  1.00 50.34  ? 195 ILE   A CA  1 
ATOM   1317 C C   . ILE   A 1 195 ? 97.479  80.792  84.760  1.00 50.34  ? 195 ILE   A C   1 
ATOM   1318 O O   . ILE   A 1 195 ? 97.482  80.659  83.528  1.00 50.34  ? 195 ILE   A O   1 
ATOM   1319 C CB  . ILE   A 1 195 ? 95.426  81.467  86.075  1.00 50.34  ? 195 ILE   A CB  1 
ATOM   1320 C CG1 . ILE   A 1 195 ? 94.086  80.958  86.598  1.00 50.34  ? 195 ILE   A CG1 1 
ATOM   1321 C CG2 . ILE   A 1 195 ? 95.166  82.431  84.936  1.00 50.34  ? 195 ILE   A CG2 1 
ATOM   1322 C CD1 . ILE   A 1 195 ? 93.159  82.059  87.075  1.00 50.34  ? 195 ILE   A CD1 1 
ATOM   1323 N N   . PHE   A 1 196 ? 98.502  81.348  85.420  1.00 49.26  ? 196 PHE   A N   1 
ATOM   1324 C CA  . PHE   A 1 196 ? 99.671  81.873  84.721  1.00 49.26  ? 196 PHE   A CA  1 
ATOM   1325 C C   . PHE   A 1 196 ? 100.382 80.778  83.936  1.00 49.26  ? 196 PHE   A C   1 
ATOM   1326 O O   . PHE   A 1 196 ? 100.695 80.953  82.752  1.00 49.26  ? 196 PHE   A O   1 
ATOM   1327 C CB  . PHE   A 1 196 ? 100.611 82.528  85.741  1.00 49.26  ? 196 PHE   A CB  1 
ATOM   1328 C CG  . PHE   A 1 196 ? 101.922 83.020  85.169  1.00 49.26  ? 196 PHE   A CG  1 
ATOM   1329 C CD1 . PHE   A 1 196 ? 103.037 82.194  85.117  1.00 49.26  ? 196 PHE   A CD1 1 
ATOM   1330 C CD2 . PHE   A 1 196 ? 102.044 84.322  84.717  1.00 49.26  ? 196 PHE   A CD2 1 
ATOM   1331 C CE1 . PHE   A 1 196 ? 104.233 82.654  84.604  1.00 49.26  ? 196 PHE   A CE1 1 
ATOM   1332 C CE2 . PHE   A 1 196 ? 103.242 84.787  84.208  1.00 49.26  ? 196 PHE   A CE2 1 
ATOM   1333 C CZ  . PHE   A 1 196 ? 104.336 83.952  84.149  1.00 49.26  ? 196 PHE   A CZ  1 
ATOM   1334 N N   . VAL   A 1 197 ? 100.625 79.632  84.577  1.00 48.54  ? 197 VAL   A N   1 
ATOM   1335 C CA  . VAL   A 1 197 ? 101.355 78.549  83.927  1.00 48.54  ? 197 VAL   A CA  1 
ATOM   1336 C C   . VAL   A 1 197 ? 100.548 77.970  82.772  1.00 48.54  ? 197 VAL   A C   1 
ATOM   1337 O O   . VAL   A 1 197 ? 101.088 77.735  81.685  1.00 48.54  ? 197 VAL   A O   1 
ATOM   1338 C CB  . VAL   A 1 197 ? 101.738 77.473  84.960  1.00 48.54  ? 197 VAL   A CB  1 
ATOM   1339 C CG1 . VAL   A 1 197 ? 102.198 76.200  84.273  1.00 48.54  ? 197 VAL   A CG1 1 
ATOM   1340 C CG2 . VAL   A 1 197 ? 102.833 77.994  85.872  1.00 48.54  ? 197 VAL   A CG2 1 
ATOM   1341 N N   . GLY   A 1 198 ? 99.243  77.759  82.970  1.00 47.09  ? 198 GLY   A N   1 
ATOM   1342 C CA  . GLY   A 1 198 ? 98.423  77.215  81.899  1.00 47.09  ? 198 GLY   A CA  1 
ATOM   1343 C C   . GLY   A 1 198 ? 98.357  78.128  80.690  1.00 47.09  ? 198 GLY   A C   1 
ATOM   1344 O O   . GLY   A 1 198 ? 98.532  77.684  79.552  1.00 47.09  ? 198 GLY   A O   1 
ATOM   1345 N N   . LEU   A 1 199 ? 98.135  79.427  80.924  1.00 44.58  ? 199 LEU   A N   1 
ATOM   1346 C CA  . LEU   A 1 199 ? 98.060  80.367  79.811  1.00 44.58  ? 199 LEU   A CA  1 
ATOM   1347 C C   . LEU   A 1 199 ? 99.399  80.499  79.095  1.00 44.58  ? 199 LEU   A C   1 
ATOM   1348 O O   . LEU   A 1 199 ? 99.449  80.481  77.859  1.00 44.58  ? 199 LEU   A O   1 
ATOM   1349 C CB  . LEU   A 1 199 ? 97.580  81.730  80.306  1.00 44.58  ? 199 LEU   A CB  1 
ATOM   1350 C CG  . LEU   A 1 199 ? 96.125  81.809  80.771  1.00 44.58  ? 199 LEU   A CG  1 
ATOM   1351 C CD1 . LEU   A 1 199 ? 95.710  83.251  80.992  1.00 44.58  ? 199 LEU   A CD1 1 
ATOM   1352 C CD2 . LEU   A 1 199 ? 95.199  81.125  79.783  1.00 44.58  ? 199 LEU   A CD2 1 
ATOM   1353 N N   . TRP   A 1 200 ? 100.499 80.608  79.844  1.00 44.08  ? 200 TRP   A N   1 
ATOM   1354 C CA  . TRP   A 1 200 ? 101.790 80.834  79.213  1.00 44.08  ? 200 TRP   A CA  1 
ATOM   1355 C C   . TRP   A 1 200 ? 102.423 79.559  78.678  1.00 44.08  ? 200 TRP   A C   1 
ATOM   1356 O O   . TRP   A 1 200 ? 103.461 79.638  78.014  1.00 44.08  ? 200 TRP   A O   1 
ATOM   1357 C CB  . TRP   A 1 200 ? 102.742 81.518  80.194  1.00 44.08  ? 200 TRP   A CB  1 
ATOM   1358 C CG  . TRP   A 1 200 ? 102.662 83.013  80.141  1.00 44.08  ? 200 TRP   A CG  1 
ATOM   1359 C CD1 . TRP   A 1 200 ? 102.288 83.843  81.152  1.00 44.08  ? 200 TRP   A CD1 1 
ATOM   1360 C CD2 . TRP   A 1 200 ? 102.950 83.856  79.017  1.00 44.08  ? 200 TRP   A CD2 1 
ATOM   1361 N NE1 . TRP   A 1 200 ? 102.332 85.149  80.735  1.00 44.08  ? 200 TRP   A NE1 1 
ATOM   1362 C CE2 . TRP   A 1 200 ? 102.734 85.184  79.427  1.00 44.08  ? 200 TRP   A CE2 1 
ATOM   1363 C CE3 . TRP   A 1 200 ? 103.372 83.616  77.706  1.00 44.08  ? 200 TRP   A CE3 1 
ATOM   1364 C CZ2 . TRP   A 1 200 ? 102.925 86.268  78.575  1.00 44.08  ? 200 TRP   A CZ2 1 
ATOM   1365 C CZ3 . TRP   A 1 200 ? 103.560 84.693  76.863  1.00 44.08  ? 200 TRP   A CZ3 1 
ATOM   1366 C CH2 . TRP   A 1 200 ? 103.337 86.001  77.300  1.00 44.08  ? 200 TRP   A CH2 1 
ATOM   1367 N N   . ILE   A 1 201 ? 101.847 78.395  78.966  1.00 46.43  ? 201 ILE   A N   1 
ATOM   1368 C CA  . ILE   A 1 201 ? 102.218 77.184  78.249  1.00 46.43  ? 201 ILE   A CA  1 
ATOM   1369 C C   . ILE   A 1 201 ? 101.351 76.997  77.005  1.00 46.43  ? 201 ILE   A C   1 
ATOM   1370 O O   . ILE   A 1 201 ? 101.845 76.544  75.967  1.00 46.43  ? 201 ILE   A O   1 
ATOM   1371 C CB  . ILE   A 1 201 ? 102.140 75.968  79.193  1.00 46.43  ? 201 ILE   A CB  1 
ATOM   1372 C CG1 . ILE   A 1 201 ? 103.309 75.992  80.180  1.00 46.43  ? 201 ILE   A CG1 1 
ATOM   1373 C CG2 . ILE   A 1 201 ? 102.129 74.651  78.426  1.00 46.43  ? 201 ILE   A CG2 1 
ATOM   1374 C CD1 . ILE   A 1 201 ? 103.439 74.735  81.015  1.00 46.43  ? 201 ILE   A CD1 1 
ATOM   1375 N N   . SER   A 1 202 ? 100.073 77.384  77.067  1.00 46.61  ? 202 SER   A N   1 
ATOM   1376 C CA  . SER   A 1 202 ? 99.207  77.241  75.902  1.00 46.61  ? 202 SER   A CA  1 
ATOM   1377 C C   . SER   A 1 202 ? 99.538  78.250  74.809  1.00 46.61  ? 202 SER   A C   1 
ATOM   1378 O O   . SER   A 1 202 ? 99.310  77.968  73.627  1.00 46.61  ? 202 SER   A O   1 
ATOM   1379 C CB  . SER   A 1 202 ? 97.746  77.375  76.322  1.00 46.61  ? 202 SER   A CB  1 
ATOM   1380 O OG  . SER   A 1 202 ? 97.359  76.301  77.159  1.00 46.61  ? 202 SER   A OG  1 
ATOM   1381 N N   . VAL   A 1 203 ? 100.053 79.429  75.176  1.00 45.20  ? 203 VAL   A N   1 
ATOM   1382 C CA  . VAL   A 1 203 ? 100.328 80.466  74.172  1.00 45.20  ? 203 VAL   A CA  1 
ATOM   1383 C C   . VAL   A 1 203 ? 101.370 80.046  73.133  1.00 45.20  ? 203 VAL   A C   1 
ATOM   1384 O O   . VAL   A 1 203 ? 101.112 80.229  71.932  1.00 45.20  ? 203 VAL   A O   1 
ATOM   1385 C CB  . VAL   A 1 203 ? 100.672 81.796  74.866  1.00 45.20  ? 203 VAL   A CB  1 
ATOM   1386 C CG1 . VAL   A 1 203 ? 101.437 82.715  73.930  1.00 45.20  ? 203 VAL   A CG1 1 
ATOM   1387 C CG2 . VAL   A 1 203 ? 99.404  82.487  75.332  1.00 45.20  ? 203 VAL   A CG2 1 
ATOM   1388 N N   . PRO   A 1 204 ? 102.550 79.510  73.500  1.00 45.77  ? 204 PRO   A N   1 
ATOM   1389 C CA  . PRO   A 1 204 ? 103.511 79.126  72.447  1.00 45.77  ? 204 PRO   A CA  1 
ATOM   1390 C C   . PRO   A 1 204 ? 103.018 78.028  71.519  1.00 45.77  ? 204 PRO   A C   1 
ATOM   1391 O O   . PRO   A 1 204 ? 103.369 78.034  70.332  1.00 45.77  ? 204 PRO   A O   1 
ATOM   1392 C CB  . PRO   A 1 204 ? 104.742 78.671  73.243  1.00 45.77  ? 204 PRO   A CB  1 
ATOM   1393 C CG  . PRO   A 1 204 ? 104.613 79.333  74.542  1.00 45.77  ? 204 PRO   A CG  1 
ATOM   1394 C CD  . PRO   A 1 204 ? 103.154 79.318  74.831  1.00 45.77  ? 204 PRO   A CD  1 
ATOM   1395 N N   . PHE   A 1 205 ? 102.224 77.081  72.019  1.00 49.10  ? 205 PHE   A N   1 
ATOM   1396 C CA  . PHE   A 1 205 ? 101.679 76.048  71.144  1.00 49.10  ? 205 PHE   A CA  1 
ATOM   1397 C C   . PHE   A 1 205 ? 100.565 76.593  70.261  1.00 49.10  ? 205 PHE   A C   1 
ATOM   1398 O O   . PHE   A 1 205 ? 100.409 76.146  69.119  1.00 49.10  ? 205 PHE   A O   1 
ATOM   1399 C CB  . PHE   A 1 205 ? 101.178 74.868  71.973  1.00 49.10  ? 205 PHE   A CB  1 
ATOM   1400 C CG  . PHE   A 1 205 ? 102.276 74.062  72.601  1.00 49.10  ? 205 PHE   A CG  1 
ATOM   1401 C CD1 . PHE   A 1 205 ? 102.834 72.988  71.929  1.00 49.10  ? 205 PHE   A CD1 1 
ATOM   1402 C CD2 . PHE   A 1 205 ? 102.757 74.383  73.857  1.00 49.10  ? 205 PHE   A CD2 1 
ATOM   1403 C CE1 . PHE   A 1 205 ? 103.846 72.246  72.503  1.00 49.10  ? 205 PHE   A CE1 1 
ATOM   1404 C CE2 . PHE   A 1 205 ? 103.769 73.646  74.436  1.00 49.10  ? 205 PHE   A CE2 1 
ATOM   1405 C CZ  . PHE   A 1 205 ? 104.314 72.576  73.758  1.00 49.10  ? 205 PHE   A CZ  1 
ATOM   1406 N N   . ALA   A 1 206 ? 99.778  77.542  70.772  1.00 47.48  ? 206 ALA   A N   1 
ATOM   1407 C CA  . ALA   A 1 206 ? 98.749  78.173  69.952  1.00 47.48  ? 206 ALA   A CA  1 
ATOM   1408 C C   . ALA   A 1 206 ? 99.365  79.013  68.841  1.00 47.48  ? 206 ALA   A C   1 
ATOM   1409 O O   . ALA   A 1 206 ? 98.849  79.039  67.718  1.00 47.48  ? 206 ALA   A O   1 
ATOM   1410 C CB  . ALA   A 1 206 ? 97.832  79.026  70.826  1.00 47.48  ? 206 ALA   A CB  1 
ATOM   1411 N N   . LEU   A 1 207 ? 100.466 79.709  69.137  1.00 47.49  ? 207 LEU   A N   1 
ATOM   1412 C CA  . LEU   A 1 207 ? 101.118 80.541  68.130  1.00 47.49  ? 207 LEU   A CA  1 
ATOM   1413 C C   . LEU   A 1 207 ? 101.731 79.709  67.012  1.00 47.49  ? 207 LEU   A C   1 
ATOM   1414 O O   . LEU   A 1 207 ? 101.840 80.187  65.878  1.00 47.49  ? 207 LEU   A O   1 
ATOM   1415 C CB  . LEU   A 1 207 ? 102.191 81.412  68.781  1.00 47.49  ? 207 LEU   A CB  1 
ATOM   1416 C CG  . LEU   A 1 207 ? 101.735 82.739  69.384  1.00 47.49  ? 207 LEU   A CG  1 
ATOM   1417 C CD1 . LEU   A 1 207 ? 102.894 83.438  70.067  1.00 47.49  ? 207 LEU   A CD1 1 
ATOM   1418 C CD2 . LEU   A 1 207 ? 101.143 83.624  68.307  1.00 47.49  ? 207 LEU   A CD2 1 
ATOM   1419 N N   . SER   A 1 208 ? 102.137 78.477  67.305  1.00 50.47  ? 208 SER   A N   1 
ATOM   1420 C CA  . SER   A 1 208 ? 102.768 77.612  66.317  1.00 50.47  ? 208 SER   A CA  1 
ATOM   1421 C C   . SER   A 1 208 ? 101.771 76.758  65.546  1.00 50.47  ? 208 SER   A C   1 
ATOM   1422 O O   . SER   A 1 208 ? 102.190 75.948  64.712  1.00 50.47  ? 208 SER   A O   1 
ATOM   1423 C CB  . SER   A 1 208 ? 103.802 76.709  66.993  1.00 50.47  ? 208 SER   A CB  1 
ATOM   1424 O OG  . SER   A 1 208 ? 104.840 77.476  67.576  1.00 50.47  ? 208 SER   A OG  1 
ATOM   1425 N N   . HIS   A 1 209 ? 100.476 76.904  65.811  1.00 54.42  ? 209 HIS   A N   1 
ATOM   1426 C CA  . HIS   A 1 209 ? 99.474  76.162  65.061  1.00 54.42  ? 209 HIS   A CA  1 
ATOM   1427 C C   . HIS   A 1 209 ? 99.439  76.654  63.615  1.00 54.42  ? 209 HIS   A C   1 
ATOM   1428 O O   . HIS   A 1 209 ? 99.464  77.864  63.371  1.00 54.42  ? 209 HIS   A O   1 
ATOM   1429 C CB  . HIS   A 1 209 ? 98.099  76.323  65.709  1.00 54.42  ? 209 HIS   A CB  1 
ATOM   1430 C CG  . HIS   A 1 209 ? 97.119  75.258  65.329  1.00 54.42  ? 209 HIS   A CG  1 
ATOM   1431 N ND1 . HIS   A 1 209 ? 96.386  75.301  64.163  1.00 54.42  ? 209 HIS   A ND1 1 
ATOM   1432 C CD2 . HIS   A 1 209 ? 96.753  74.117  65.960  1.00 54.42  ? 209 HIS   A CD2 1 
ATOM   1433 C CE1 . HIS   A 1 209 ? 95.610  74.235  64.093  1.00 54.42  ? 209 HIS   A CE1 1 
ATOM   1434 N NE2 . HIS   A 1 209 ? 95.813  73.500  65.171  1.00 54.42  ? 209 HIS   A NE2 1 
ATOM   1435 N N   . PRO   A 1 210 ? 99.396  75.744  62.635  1.00 56.97  ? 210 PRO   A N   1 
ATOM   1436 C CA  . PRO   A 1 210 ? 99.429  76.182  61.227  1.00 56.97  ? 210 PRO   A CA  1 
ATOM   1437 C C   . PRO   A 1 210 ? 98.200  76.962  60.790  1.00 56.97  ? 210 PRO   A C   1 
ATOM   1438 O O   . PRO   A 1 210 ? 98.266  77.657  59.769  1.00 56.97  ? 210 PRO   A O   1 
ATOM   1439 C CB  . PRO   A 1 210 ? 99.566  74.872  60.437  1.00 56.97  ? 210 PRO   A CB  1 
ATOM   1440 C CG  . PRO   A 1 210 ? 99.381  73.764  61.397  1.00 56.97  ? 210 PRO   A CG  1 
ATOM   1441 C CD  . PRO   A 1 210 ? 99.268  74.286  62.787  1.00 56.97  ? 210 PRO   A CD  1 
ATOM   1442 N N   . ALA   A 1 211 ? 97.084  76.866  61.516  1.00 55.83  ? 211 ALA   A N   1 
ATOM   1443 C CA  . ALA   A 1 211 ? 95.909  77.656  61.166  1.00 55.83  ? 211 ALA   A CA  1 
ATOM   1444 C C   . ALA   A 1 211 ? 96.117  79.131  61.486  1.00 55.83  ? 211 ALA   A C   1 
ATOM   1445 O O   . ALA   A 1 211 ? 95.629  80.004  60.759  1.00 55.83  ? 211 ALA   A O   1 
ATOM   1446 C CB  . ALA   A 1 211 ? 94.679  77.123  61.895  1.00 55.83  ? 211 ALA   A CB  1 
ATOM   1447 N N   . VAL   A 1 212 ? 96.833  79.426  62.570  1.00 52.35  ? 212 VAL   A N   1 
ATOM   1448 C CA  . VAL   A 1 212 ? 97.031  80.806  62.993  1.00 52.35  ? 212 VAL   A CA  1 
ATOM   1449 C C   . VAL   A 1 212 ? 98.011  81.494  62.053  1.00 52.35  ? 212 VAL   A C   1 
ATOM   1450 O O   . VAL   A 1 212 ? 99.085  80.959  61.747  1.00 52.35  ? 212 VAL   A O   1 
ATOM   1451 C CB  . VAL   A 1 212 ? 97.525  80.854  64.446  1.00 52.35  ? 212 VAL   A CB  1 
ATOM   1452 C CG1 . VAL   A 1 212 ? 97.616  82.288  64.934  1.00 52.35  ? 212 VAL   A CG1 1 
ATOM   1453 C CG2 . VAL   A 1 212 ? 96.608  80.042  65.339  1.00 52.35  ? 212 VAL   A CG2 1 
ATOM   1454 N N   . ALA   A 1 213 ? 97.642  82.683  61.585  1.00 57.00  ? 213 ALA   A N   1 
ATOM   1455 C CA  . ALA   A 1 213 ? 98.516  83.487  60.746  1.00 57.00  ? 213 ALA   A CA  1 
ATOM   1456 C C   . ALA   A 1 213 ? 99.518  84.249  61.612  1.00 57.00  ? 213 ALA   A C   1 
ATOM   1457 O O   . ALA   A 1 213 ? 99.605  84.056  62.828  1.00 57.00  ? 213 ALA   A O   1 
ATOM   1458 C CB  . ALA   A 1 213 ? 97.695  84.441  59.883  1.00 57.00  ? 213 ALA   A CB  1 
ATOM   1459 N N   . ASP   A 1 214 ? 100.290 85.126  60.975  1.00 56.75  ? 214 ASP   A N   1 
ATOM   1460 C CA  . ASP   A 1 214 ? 101.267 85.937  61.693  1.00 56.75  ? 214 ASP   A CA  1 
ATOM   1461 C C   . ASP   A 1 214 ? 100.542 86.930  62.593  1.00 56.75  ? 214 ASP   A C   1 
ATOM   1462 O O   . ASP   A 1 214 ? 99.716  87.718  62.121  1.00 56.75  ? 214 ASP   A O   1 
ATOM   1463 C CB  . ASP   A 1 214 ? 102.176 86.663  60.705  1.00 56.75  ? 214 ASP   A CB  1 
ATOM   1464 C CG  . ASP   A 1 214 ? 103.317 87.396  61.387  1.00 56.75  ? 214 ASP   A CG  1 
ATOM   1465 O OD1 . ASP   A 1 214 ? 103.584 87.124  62.575  1.00 56.75  ? 214 ASP   A OD1 1 
ATOM   1466 O OD2 . ASP   A 1 214 ? 103.950 88.248  60.730  1.00 56.75  ? 214 ASP   A OD2 1 
ATOM   1467 N N   . ILE   A 1 215 ? 100.851 86.890  63.891  1.00 50.42  ? 215 ILE   A N   1 
ATOM   1468 C CA  . ILE   A 1 215 ? 100.138 87.720  64.856  1.00 50.42  ? 215 ILE   A CA  1 
ATOM   1469 C C   . ILE   A 1 215 ? 100.477 89.197  64.671  1.00 50.42  ? 215 ILE   A C   1 
ATOM   1470 O O   . ILE   A 1 215 ? 99.635  90.068  64.921  1.00 50.42  ? 215 ILE   A O   1 
ATOM   1471 C CB  . ILE   A 1 215 ? 100.424 87.220  66.288  1.00 50.42  ? 215 ILE   A CB  1 
ATOM   1472 C CG1 . ILE   A 1 215 ? 99.502  87.897  67.303  1.00 50.42  ? 215 ILE   A CG1 1 
ATOM   1473 C CG2 . ILE   A 1 215 ? 101.890 87.397  66.669  1.00 50.42  ? 215 ILE   A CG2 1 
ATOM   1474 C CD1 . ILE   A 1 215 ? 99.511  87.228  68.651  1.00 50.42  ? 215 ILE   A CD1 1 
ATOM   1475 N N   . GLY   A 1 216 ? 101.696 89.509  64.230  1.00 51.03  ? 216 GLY   A N   1 
ATOM   1476 C CA  . GLY   A 1 216 ? 102.054 90.899  64.001  1.00 51.03  ? 216 GLY   A CA  1 
ATOM   1477 C C   . GLY   A 1 216 ? 101.415 91.478  62.753  1.00 51.03  ? 216 GLY   A C   1 
ATOM   1478 O O   . GLY   A 1 216 ? 101.087 92.667  62.709  1.00 51.03  ? 216 GLY   A O   1 
ATOM   1479 N N   . PHE   A 1 217 ? 101.246 90.652  61.718  1.00 54.17  ? 217 PHE   A N   1 
ATOM   1480 C CA  . PHE   A 1 217 ? 100.684 91.134  60.460  1.00 54.17  ? 217 PHE   A CA  1 
ATOM   1481 C C   . PHE   A 1 217 ? 99.215  91.507  60.613  1.00 54.17  ? 217 PHE   A C   1 
ATOM   1482 O O   . PHE   A 1 217 ? 98.781  92.550  60.114  1.00 54.17  ? 217 PHE   A O   1 
ATOM   1483 C CB  . PHE   A 1 217 ? 100.870 90.075  59.372  1.00 54.17  ? 217 PHE   A CB  1 
ATOM   1484 C CG  . PHE   A 1 217 ? 100.249 90.434  58.047  1.00 54.17  ? 217 PHE   A CG  1 
ATOM   1485 C CD1 . PHE   A 1 217 ? 100.961 91.169  57.114  1.00 54.17  ? 217 PHE   A CD1 1 
ATOM   1486 C CD2 . PHE   A 1 217 ? 98.975  89.998  57.714  1.00 54.17  ? 217 PHE   A CD2 1 
ATOM   1487 C CE1 . PHE   A 1 217 ? 100.404 91.492  55.892  1.00 54.17  ? 217 PHE   A CE1 1 
ATOM   1488 C CE2 . PHE   A 1 217 ? 98.413  90.319  56.494  1.00 54.17  ? 217 PHE   A CE2 1 
ATOM   1489 C CZ  . PHE   A 1 217 ? 99.130  91.065  55.581  1.00 54.17  ? 217 PHE   A CZ  1 
ATOM   1490 N N   . THR   A 1 218 ? 98.435  90.672  61.302  1.00 50.27  ? 218 THR   A N   1 
ATOM   1491 C CA  . THR   A 1 218 ? 97.007  90.924  61.450  1.00 50.27  ? 218 THR   A CA  1 
ATOM   1492 C C   . THR   A 1 218 ? 96.698  92.035  62.443  1.00 50.27  ? 218 THR   A C   1 
ATOM   1493 O O   . THR   A 1 218 ? 95.536  92.439  62.545  1.00 50.27  ? 218 THR   A O   1 
ATOM   1494 C CB  . THR   A 1 218 ? 96.280  89.647  61.874  1.00 50.27  ? 218 THR   A CB  1 
ATOM   1495 O OG1 . THR   A 1 218 ? 96.577  89.360  63.245  1.00 50.27  ? 218 THR   A OG1 1 
ATOM   1496 C CG2 . THR   A 1 218 ? 96.704  88.476  61.006  1.00 50.27  ? 218 THR   A CG2 1 
ATOM   1497 N N   . ALA   A 1 219 ? 97.695  92.523  63.181  1.00 49.38  ? 219 ALA   A N   1 
ATOM   1498 C CA  . ALA   A 1 219 ? 97.465  93.647  64.081  1.00 49.38  ? 219 ALA   A CA  1 
ATOM   1499 C C   . ALA   A 1 219 ? 97.152  94.922  63.307  1.00 49.38  ? 219 ALA   A C   1 
ATOM   1500 O O   . ALA   A 1 219 ? 96.331  95.735  63.745  1.00 49.38  ? 219 ALA   A O   1 
ATOM   1501 C CB  . ALA   A 1 219 ? 98.679  93.851  64.985  1.00 49.38  ? 219 ALA   A CB  1 
ATOM   1502 N N   . VAL   A 1 220 ? 97.793  95.113  62.155  1.00 53.62  ? 220 VAL   A N   1 
ATOM   1503 C CA  . VAL   A 1 220 ? 97.609  96.307  61.341  1.00 53.62  ? 220 VAL   A CA  1 
ATOM   1504 C C   . VAL   A 1 220 ? 96.998  96.006  59.982  1.00 53.62  ? 220 VAL   A C   1 
ATOM   1505 O O   . VAL   A 1 220 ? 96.762  96.936  59.206  1.00 53.62  ? 220 VAL   A O   1 
ATOM   1506 C CB  . VAL   A 1 220 ? 98.936  97.072  61.165  1.00 53.62  ? 220 VAL   A CB  1 
ATOM   1507 C CG1 . VAL   A 1 220 ? 99.405  97.629  62.496  1.00 53.62  ? 220 VAL   A CG1 1 
ATOM   1508 C CG2 . VAL   A 1 220 ? 99.992  96.164  60.560  1.00 53.62  ? 220 VAL   A CG2 1 
ATOM   1509 N N   . HIS   A 1 221 ? 96.734  94.741  59.667  1.00 59.11  ? 221 HIS   A N   1 
ATOM   1510 C CA  . HIS   A 1 221 ? 96.173  94.360  58.381  1.00 59.11  ? 221 HIS   A CA  1 
ATOM   1511 C C   . HIS   A 1 221 ? 94.989  93.430  58.601  1.00 59.11  ? 221 HIS   A C   1 
ATOM   1512 O O   . HIS   A 1 221 ? 94.865  92.785  59.645  1.00 59.11  ? 221 HIS   A O   1 
ATOM   1513 C CB  . HIS   A 1 221 ? 97.220  93.685  57.487  1.00 59.11  ? 221 HIS   A CB  1 
ATOM   1514 C CG  . HIS   A 1 221 ? 98.123  94.649  56.782  1.00 59.11  ? 221 HIS   A CG  1 
ATOM   1515 N ND1 . HIS   A 1 221 ? 99.495  94.520  56.784  1.00 59.11  ? 221 HIS   A ND1 1 
ATOM   1516 C CD2 . HIS   A 1 221 ? 97.850  95.758  56.056  1.00 59.11  ? 221 HIS   A CD2 1 
ATOM   1517 C CE1 . HIS   A 1 221 ? 100.029 95.507  56.088  1.00 59.11  ? 221 HIS   A CE1 1 
ATOM   1518 N NE2 . HIS   A 1 221 ? 99.052  96.273  55.635  1.00 59.11  ? 221 HIS   A NE2 1 
ATOM   1519 N N   . ALA   A 1 222 ? 94.112  93.370  57.603  1.00 60.12  ? 222 ALA   A N   1 
ATOM   1520 C CA  . ALA   A 1 222 ? 92.874  92.606  57.686  1.00 60.12  ? 222 ALA   A CA  1 
ATOM   1521 C C   . ALA   A 1 222 ? 92.894  91.494  56.648  1.00 60.12  ? 222 ALA   A C   1 
ATOM   1522 O O   . ALA   A 1 222 ? 92.928  91.768  55.444  1.00 60.12  ? 222 ALA   A O   1 
ATOM   1523 C CB  . ALA   A 1 222 ? 91.660  93.513  57.474  1.00 60.12  ? 222 ALA   A CB  1 
ATOM   1524 N N   . LYS   A 1 223 ? 92.875  90.246  57.113  1.00 60.28  ? 223 LYS   A N   1 
ATOM   1525 C CA  . LYS   A 1 223 ? 92.757  89.093  56.228  1.00 60.28  ? 223 LYS   A CA  1 
ATOM   1526 C C   . LYS   A 1 223 ? 91.536  88.238  56.534  1.00 60.28  ? 223 LYS   A C   1 
ATOM   1527 O O   . LYS   A 1 223 ? 90.814  87.848  55.609  1.00 60.28  ? 223 LYS   A O   1 
ATOM   1528 C CB  . LYS   A 1 223 ? 94.042  88.245  56.277  1.00 60.28  ? 223 LYS   A CB  1 
ATOM   1529 C CG  . LYS   A 1 223 ? 94.512  87.836  57.664  1.00 60.28  ? 223 LYS   A CG  1 
ATOM   1530 C CD  . LYS   A 1 223 ? 95.821  87.059  57.596  1.00 60.28  ? 223 LYS   A CD  1 
ATOM   1531 C CE  . LYS   A 1 223 ? 95.803  86.019  56.485  1.00 60.28  ? 223 LYS   A CE  1 
ATOM   1532 N NZ  . LYS   A 1 223 ? 97.056  85.217  56.454  1.00 60.28  ? 223 LYS   A NZ  1 
ATOM   1533 N N   . TYR   A 1 224 ? 91.280  87.931  57.806  1.00 57.40  ? 224 TYR   A N   1 
ATOM   1534 C CA  . TYR   A 1 224 ? 90.097  87.174  58.197  1.00 57.40  ? 224 TYR   A CA  1 
ATOM   1535 C C   . TYR   A 1 224 ? 89.013  88.045  58.810  1.00 57.40  ? 224 TYR   A C   1 
ATOM   1536 O O   . TYR   A 1 224 ? 87.826  87.767  58.618  1.00 57.40  ? 224 TYR   A O   1 
ATOM   1537 C CB  . TYR   A 1 224 ? 90.474  86.070  59.191  1.00 57.40  ? 224 TYR   A CB  1 
ATOM   1538 C CG  . TYR   A 1 224 ? 91.507  85.100  58.667  1.00 57.40  ? 224 TYR   A CG  1 
ATOM   1539 C CD1 . TYR   A 1 224 ? 91.274  84.363  57.514  1.00 57.40  ? 224 TYR   A CD1 1 
ATOM   1540 C CD2 . TYR   A 1 224 ? 92.716  84.924  59.325  1.00 57.40  ? 224 TYR   A CD2 1 
ATOM   1541 C CE1 . TYR   A 1 224 ? 92.217  83.477  57.032  1.00 57.40  ? 224 TYR   A CE1 1 
ATOM   1542 C CE2 . TYR   A 1 224 ? 93.664  84.041  58.850  1.00 57.40  ? 224 TYR   A CE2 1 
ATOM   1543 C CZ  . TYR   A 1 224 ? 93.410  83.322  57.704  1.00 57.40  ? 224 TYR   A CZ  1 
ATOM   1544 O OH  . TYR   A 1 224 ? 94.354  82.441  57.231  1.00 57.40  ? 224 TYR   A OH  1 
ATOM   1545 N N   . GLN   A 1 225 ? 89.397  89.085  59.541  1.00 54.07  ? 225 GLN   A N   1 
ATOM   1546 C CA  . GLN   A 1 225 ? 88.460  90.045  60.103  1.00 54.07  ? 225 GLN   A CA  1 
ATOM   1547 C C   . GLN   A 1 225 ? 89.180  91.384  60.217  1.00 54.07  ? 225 GLN   A C   1 
ATOM   1548 O O   . GLN   A 1 225 ? 90.288  91.553  59.699  1.00 54.07  ? 225 GLN   A O   1 
ATOM   1549 C CB  . GLN   A 1 225 ? 87.909  89.537  61.442  1.00 54.07  ? 225 GLN   A CB  1 
ATOM   1550 C CG  . GLN   A 1 225 ? 88.897  89.574  62.596  1.00 54.07  ? 225 GLN   A CG  1 
ATOM   1551 C CD  . GLN   A 1 225 ? 88.348  88.923  63.847  1.00 54.07  ? 225 GLN   A CD  1 
ATOM   1552 O OE1 . GLN   A 1 225 ? 87.822  87.813  63.802  1.00 54.07  ? 225 GLN   A OE1 1 
ATOM   1553 N NE2 . GLN   A 1 225 ? 88.463  89.615  64.973  1.00 54.07  ? 225 GLN   A NE2 1 
ATOM   1554 N N   . LYS   A 1 226 ? 88.545  92.343  60.887  1.00 54.85  ? 226 LYS   A N   1 
ATOM   1555 C CA  . LYS   A 1 226 ? 89.173  93.634  61.113  1.00 54.85  ? 226 LYS   A CA  1 
ATOM   1556 C C   . LYS   A 1 226 ? 90.418  93.462  61.984  1.00 54.85  ? 226 LYS   A C   1 
ATOM   1557 O O   . LYS   A 1 226 ? 90.491  92.529  62.790  1.00 54.85  ? 226 LYS   A O   1 
ATOM   1558 C CB  . LYS   A 1 226 ? 88.192  94.596  61.779  1.00 54.85  ? 226 LYS   A CB  1 
ATOM   1559 C CG  . LYS   A 1 226 ? 86.965  94.918  60.944  1.00 54.85  ? 226 LYS   A CG  1 
ATOM   1560 C CD  . LYS   A 1 226 ? 86.355  96.246  61.361  1.00 54.85  ? 226 LYS   A CD  1 
ATOM   1561 C CE  . LYS   A 1 226 ? 84.923  96.382  60.872  1.00 54.85  ? 226 LYS   A CE  1 
ATOM   1562 N NZ  . LYS   A 1 226 ? 83.939  95.918  61.888  1.00 54.85  ? 226 LYS   A NZ  1 
ATOM   1563 N N   . PRO   A 1 227 ? 91.426  94.323  61.810  1.00 48.27  ? 227 PRO   A N   1 
ATOM   1564 C CA  . PRO   A 1 227 ? 92.652  94.204  62.612  1.00 48.27  ? 227 PRO   A CA  1 
ATOM   1565 C C   . PRO   A 1 227 ? 92.370  94.295  64.105  1.00 48.27  ? 227 PRO   A C   1 
ATOM   1566 O O   . PRO   A 1 227 ? 91.571  95.116  64.559  1.00 48.27  ? 227 PRO   A O   1 
ATOM   1567 C CB  . PRO   A 1 227 ? 93.500  95.383  62.127  1.00 48.27  ? 227 PRO   A CB  1 
ATOM   1568 C CG  . PRO   A 1 227 ? 93.038  95.609  60.732  1.00 48.27  ? 227 PRO   A CG  1 
ATOM   1569 C CD  . PRO   A 1 227 ? 91.561  95.349  60.762  1.00 48.27  ? 227 PRO   A CD  1 
ATOM   1570 N N   . TRP   A 1 228 ? 93.042  93.435  64.870  1.00 40.66  ? 228 TRP   A N   1 
ATOM   1571 C CA  . TRP   A 1 228 ? 92.727  93.278  66.283  1.00 40.66  ? 228 TRP   A CA  1 
ATOM   1572 C C   . TRP   A 1 228 ? 93.310  94.377  67.159  1.00 40.66  ? 228 TRP   A C   1 
ATOM   1573 O O   . TRP   A 1 228 ? 92.988  94.421  68.351  1.00 40.66  ? 228 TRP   A O   1 
ATOM   1574 C CB  . TRP   A 1 228 ? 93.184  91.901  66.778  1.00 40.66  ? 228 TRP   A CB  1 
ATOM   1575 C CG  . TRP   A 1 228 ? 94.653  91.631  66.675  1.00 40.66  ? 228 TRP   A CG  1 
ATOM   1576 C CD1 . TRP   A 1 228 ? 95.294  90.989  65.658  1.00 40.66  ? 228 TRP   A CD1 1 
ATOM   1577 C CD2 . TRP   A 1 228 ? 95.661  91.959  67.639  1.00 40.66  ? 228 TRP   A CD2 1 
ATOM   1578 N NE1 . TRP   A 1 228 ? 96.638  90.913  65.919  1.00 40.66  ? 228 TRP   A NE1 1 
ATOM   1579 C CE2 . TRP   A 1 228 ? 96.890  91.502  67.129  1.00 40.66  ? 228 TRP   A CE2 1 
ATOM   1580 C CE3 . TRP   A 1 228 ? 95.644  92.603  68.879  1.00 40.66  ? 228 TRP   A CE3 1 
ATOM   1581 C CZ2 . TRP   A 1 228 ? 98.088  91.666  67.816  1.00 40.66  ? 228 TRP   A CZ2 1 
ATOM   1582 C CZ3 . TRP   A 1 228 ? 96.836  92.766  69.557  1.00 40.66  ? 228 TRP   A CZ3 1 
ATOM   1583 C CH2 . TRP   A 1 228 ? 98.040  92.300  69.025  1.00 40.66  ? 228 TRP   A CH2 1 
ATOM   1584 N N   . LEU   A 1 229 ? 94.158  95.252  66.616  1.00 44.01  ? 229 LEU   A N   1 
ATOM   1585 C CA  . LEU   A 1 229 ? 94.534  96.450  67.361  1.00 44.01  ? 229 LEU   A CA  1 
ATOM   1586 C C   . LEU   A 1 229 ? 93.337  97.369  67.557  1.00 44.01  ? 229 LEU   A C   1 
ATOM   1587 O O   . LEU   A 1 229 ? 93.160  97.947  68.635  1.00 44.01  ? 229 LEU   A O   1 
ATOM   1588 C CB  . LEU   A 1 229 ? 95.664  97.193  66.653  1.00 44.01  ? 229 LEU   A CB  1 
ATOM   1589 C CG  . LEU   A 1 229 ? 97.081  96.669  66.868  1.00 44.01  ? 229 LEU   A CG  1 
ATOM   1590 C CD1 . LEU   A 1 229 ? 98.062  97.416  65.983  1.00 44.01  ? 229 LEU   A CD1 1 
ATOM   1591 C CD2 . LEU   A 1 229 ? 97.467  96.812  68.326  1.00 44.01  ? 229 LEU   A CD2 1 
ATOM   1592 N N   . GLY   A 1 230 ? 92.508  97.512  66.532  1.00 50.45  ? 230 GLY   A N   1 
ATOM   1593 C CA  . GLY   A 1 230 ? 91.355  98.382  66.587  1.00 50.45  ? 230 GLY   A CA  1 
ATOM   1594 C C   . GLY   A 1 230 ? 91.678  99.801  66.152  1.00 50.45  ? 230 GLY   A C   1 
ATOM   1595 O O   . GLY   A 1 230 ? 92.828  100.235 66.131  1.00 50.45  ? 230 GLY   A O   1 
ATOM   1596 N N   . THR   A 1 231 ? 90.626  100.531 65.790  1.00 62.18  ? 231 THR   A N   1 
ATOM   1597 C CA  . THR   A 1 231 ? 90.747  101.921 65.376  1.00 62.18  ? 231 THR   A CA  1 
ATOM   1598 C C   . THR   A 1 231 ? 89.727  102.757 66.132  1.00 62.18  ? 231 THR   A C   1 
ATOM   1599 O O   . THR   A 1 231 ? 88.619  102.300 66.423  1.00 62.18  ? 231 THR   A O   1 
ATOM   1600 C CB  . THR   A 1 231 ? 90.535  102.109 63.860  1.00 62.18  ? 231 THR   A CB  1 
ATOM   1601 O OG1 . THR   A 1 231 ? 89.158  101.887 63.532  1.00 62.18  ? 231 THR   A OG1 1 
ATOM   1602 C CG2 . THR   A 1 231 ? 91.416  101.166 63.046  1.00 62.18  ? 231 THR   A CG2 1 
ATOM   1603 N N   . VAL   A 1 232 ? 90.115  103.988 66.450  1.00 62.28  ? 232 VAL   A N   1 
ATOM   1604 C CA  . VAL   A 1 232 ? 89.241  104.954 67.105  1.00 62.28  ? 232 VAL   A CA  1 
ATOM   1605 C C   . VAL   A 1 232 ? 89.081  106.142 66.169  1.00 62.28  ? 232 VAL   A C   1 
ATOM   1606 O O   . VAL   A 1 232 ? 90.071  106.784 65.797  1.00 62.28  ? 232 VAL   A O   1 
ATOM   1607 C CB  . VAL   A 1 232 ? 89.793  105.400 68.469  1.00 62.28  ? 232 VAL   A CB  1 
ATOM   1608 C CG1 . VAL   A 1 232 ? 88.763  106.233 69.210  1.00 62.28  ? 232 VAL   A CG1 1 
ATOM   1609 C CG2 . VAL   A 1 232 ? 90.194  104.195 69.298  1.00 62.28  ? 232 VAL   A CG2 1 
ATOM   1610 N N   . ASP   A 1 233 ? 87.840  106.434 65.790  1.00 70.74  ? 233 ASP   A N   1 
ATOM   1611 C CA  . ASP   A 1 233 ? 87.567  107.561 64.915  1.00 70.74  ? 233 ASP   A CA  1 
ATOM   1612 C C   . ASP   A 1 233 ? 87.718  108.874 65.678  1.00 70.74  ? 233 ASP   A C   1 
ATOM   1613 O O   . ASP   A 1 233 ? 87.846  108.905 66.905  1.00 70.74  ? 233 ASP   A O   1 
ATOM   1614 C CB  . ASP   A 1 233 ? 86.165  107.451 64.319  1.00 70.74  ? 233 ASP   A CB  1 
ATOM   1615 C CG  . ASP   A 1 233 ? 86.040  106.309 63.333  1.00 70.74  ? 233 ASP   A CG  1 
ATOM   1616 O OD1 . ASP   A 1 233 ? 87.054  105.962 62.694  1.00 70.74  ? 233 ASP   A OD1 1 
ATOM   1617 O OD2 . ASP   A 1 233 ? 84.927  105.760 63.197  1.00 70.74  ? 233 ASP   A OD2 1 
ATOM   1618 N N   . SER   A 1 234 ? 87.709  109.976 64.924  1.00 71.43  ? 234 SER   A N   1 
ATOM   1619 C CA  . SER   A 1 234 ? 87.842  111.296 65.532  1.00 71.43  ? 234 SER   A CA  1 
ATOM   1620 C C   . SER   A 1 234 ? 86.637  111.633 66.403  1.00 71.43  ? 234 SER   A C   1 
ATOM   1621 O O   . SER   A 1 234 ? 86.777  112.303 67.432  1.00 71.43  ? 234 SER   A O   1 
ATOM   1622 C CB  . SER   A 1 234 ? 88.032  112.354 64.444  1.00 71.43  ? 234 SER   A CB  1 
ATOM   1623 O OG  . SER   A 1 234 ? 89.202  112.102 63.686  1.00 71.43  ? 234 SER   A OG  1 
ATOM   1624 N N   . SER   A 1 235 ? 85.446  111.181 66.004  1.00 68.29  ? 235 SER   A N   1 
ATOM   1625 C CA  . SER   A 1 235 ? 84.244  111.480 66.774  1.00 68.29  ? 235 SER   A CA  1 
ATOM   1626 C C   . SER   A 1 235 ? 84.156  110.645 68.045  1.00 68.29  ? 235 SER   A C   1 
ATOM   1627 O O   . SER   A 1 235 ? 83.573  111.093 69.039  1.00 68.29  ? 235 SER   A O   1 
ATOM   1628 C CB  . SER   A 1 235 ? 83.003  111.257 65.911  1.00 68.29  ? 235 SER   A CB  1 
ATOM   1629 O OG  . SER   A 1 235 ? 83.019  109.969 65.323  1.00 68.29  ? 235 SER   A OG  1 
ATOM   1630 N N   . GLU   A 1 236 ? 84.722  109.438 68.036  1.00 63.90  ? 236 GLU   A N   1 
ATOM   1631 C CA  . GLU   A 1 236 ? 84.590  108.514 69.155  1.00 63.90  ? 236 GLU   A CA  1 
ATOM   1632 C C   . GLU   A 1 236 ? 85.521  108.831 70.319  1.00 63.90  ? 236 GLU   A C   1 
ATOM   1633 O O   . GLU   A 1 236 ? 85.391  108.198 71.373  1.00 63.90  ? 236 GLU   A O   1 
ATOM   1634 C CB  . GLU   A 1 236 ? 84.845  107.084 68.676  1.00 63.90  ? 236 GLU   A CB  1 
ATOM   1635 C CG  . GLU   A 1 236 ? 83.755  106.534 67.776  1.00 63.90  ? 236 GLU   A CG  1 
ATOM   1636 C CD  . GLU   A 1 236 ? 84.145  105.222 67.129  1.00 63.90  ? 236 GLU   A CD  1 
ATOM   1637 O OE1 . GLU   A 1 236 ? 85.318  104.817 67.265  1.00 63.90  ? 236 GLU   A OE1 1 
ATOM   1638 O OE2 . GLU   A 1 236 ? 83.279  104.595 66.485  1.00 63.90  ? 236 GLU   A OE2 1 
ATOM   1639 N N   . VAL   A 1 237 ? 86.437  109.791 70.156  1.00 57.69  ? 237 VAL   A N   1 
ATOM   1640 C CA  . VAL   A 1 237 ? 87.443  110.073 71.179  1.00 57.69  ? 237 VAL   A CA  1 
ATOM   1641 C C   . VAL   A 1 237 ? 86.783  110.503 72.483  1.00 57.69  ? 237 VAL   A C   1 
ATOM   1642 O O   . VAL   A 1 237 ? 87.216  110.113 73.574  1.00 57.69  ? 237 VAL   A O   1 
ATOM   1643 C CB  . VAL   A 1 237 ? 88.434  111.135 70.666  1.00 57.69  ? 237 VAL   A CB  1 
ATOM   1644 C CG1 . VAL   A 1 237 ? 89.469  111.469 71.727  1.00 57.69  ? 237 VAL   A CG1 1 
ATOM   1645 C CG2 . VAL   A 1 237 ? 89.111  110.655 69.397  1.00 57.69  ? 237 VAL   A CG2 1 
ATOM   1646 N N   . TYR   A 1 238 ? 85.719  111.303 72.394  1.00 59.40  ? 238 TYR   A N   1 
ATOM   1647 C CA  . TYR   A 1 238 ? 84.988  111.685 73.596  1.00 59.40  ? 238 TYR   A CA  1 
ATOM   1648 C C   . TYR   A 1 238 ? 84.269  110.497 74.220  1.00 59.40  ? 238 TYR   A C   1 
ATOM   1649 O O   . TYR   A 1 238 ? 84.148  110.425 75.448  1.00 59.40  ? 238 TYR   A O   1 
ATOM   1650 C CB  . TYR   A 1 238 ? 83.996  112.802 73.276  1.00 59.40  ? 238 TYR   A CB  1 
ATOM   1651 C CG  . TYR   A 1 238 ? 84.658  114.114 72.927  1.00 59.40  ? 238 TYR   A CG  1 
ATOM   1652 C CD1 . TYR   A 1 238 ? 85.594  114.687 73.778  1.00 59.40  ? 238 TYR   A CD1 1 
ATOM   1653 C CD2 . TYR   A 1 238 ? 84.350  114.778 71.748  1.00 59.40  ? 238 TYR   A CD2 1 
ATOM   1654 C CE1 . TYR   A 1 238 ? 86.205  115.884 73.463  1.00 59.40  ? 238 TYR   A CE1 1 
ATOM   1655 C CE2 . TYR   A 1 238 ? 84.954  115.976 71.426  1.00 59.40  ? 238 TYR   A CE2 1 
ATOM   1656 C CZ  . TYR   A 1 238 ? 85.881  116.525 72.286  1.00 59.40  ? 238 TYR   A CZ  1 
ATOM   1657 O OH  . TYR   A 1 238 ? 86.485  117.719 71.969  1.00 59.40  ? 238 TYR   A OH  1 
ATOM   1658 N N   . SER   A 1 239 ? 83.778  109.562 73.401  1.00 54.10  ? 239 SER   A N   1 
ATOM   1659 C CA  . SER   A 1 239 ? 83.114  108.386 73.955  1.00 54.10  ? 239 SER   A CA  1 
ATOM   1660 C C   . SER   A 1 239 ? 84.125  107.414 74.548  1.00 54.10  ? 239 SER   A C   1 
ATOM   1661 O O   . SER   A 1 239 ? 83.901  106.870 75.637  1.00 54.10  ? 239 SER   A O   1 
ATOM   1662 C CB  . SER   A 1 239 ? 82.275  107.698 72.880  1.00 54.10  ? 239 SER   A CB  1 
ATOM   1663 O OG  . SER   A 1 239 ? 83.098  107.022 71.947  1.00 54.10  ? 239 SER   A OG  1 
ATOM   1664 N N   . TRP   A 1 240 ? 85.244  107.199 73.846  1.00 45.18  ? 240 TRP   A N   1 
ATOM   1665 C CA  . TRP   A 1 240 ? 86.288  106.286 74.308  1.00 45.18  ? 240 TRP   A CA  1 
ATOM   1666 C C   . TRP   A 1 240 ? 86.772  106.667 75.700  1.00 45.18  ? 240 TRP   A C   1 
ATOM   1667 O O   . TRP   A 1 240 ? 86.768  105.839 76.620  1.00 45.18  ? 240 TRP   A O   1 
ATOM   1668 C CB  . TRP   A 1 240 ? 87.442  106.292 73.301  1.00 45.18  ? 240 TRP   A CB  1 
ATOM   1669 C CG  . TRP   A 1 240 ? 88.539  105.291 73.544  1.00 45.18  ? 240 TRP   A CG  1 
ATOM   1670 C CD1 . TRP   A 1 240 ? 88.701  104.092 72.915  1.00 45.18  ? 240 TRP   A CD1 1 
ATOM   1671 C CD2 . TRP   A 1 240 ? 89.654  105.427 74.435  1.00 45.18  ? 240 TRP   A CD2 1 
ATOM   1672 N NE1 . TRP   A 1 240 ? 89.828  103.461 73.378  1.00 45.18  ? 240 TRP   A NE1 1 
ATOM   1673 C CE2 . TRP   A 1 240 ? 90.432  104.261 74.311  1.00 45.18  ? 240 TRP   A CE2 1 
ATOM   1674 C CE3 . TRP   A 1 240 ? 90.065  106.416 75.334  1.00 45.18  ? 240 TRP   A CE3 1 
ATOM   1675 C CZ2 . TRP   A 1 240 ? 91.592  104.055 75.051  1.00 45.18  ? 240 TRP   A CZ2 1 
ATOM   1676 C CZ3 . TRP   A 1 240 ? 91.215  106.209 76.069  1.00 45.18  ? 240 TRP   A CZ3 1 
ATOM   1677 C CH2 . TRP   A 1 240 ? 91.965  105.039 75.923  1.00 45.18  ? 240 TRP   A CH2 1 
ATOM   1678 N N   . LEU   A 1 241 ? 87.149  107.938 75.881  1.00 45.33  ? 241 LEU   A N   1 
ATOM   1679 C CA  . LEU   A 1 241 ? 87.516  108.435 77.202  1.00 45.33  ? 241 LEU   A CA  1 
ATOM   1680 C C   . LEU   A 1 241 ? 86.376  108.249 78.191  1.00 45.33  ? 241 LEU   A C   1 
ATOM   1681 O O   . LEU   A 1 241 ? 86.601  107.842 79.338  1.00 45.33  ? 241 LEU   A O   1 
ATOM   1682 C CB  . LEU   A 1 241 ? 87.906  109.911 77.117  1.00 45.33  ? 241 LEU   A CB  1 
ATOM   1683 C CG  . LEU   A 1 241 ? 89.161  110.280 76.328  1.00 45.33  ? 241 LEU   A CG  1 
ATOM   1684 C CD1 . LEU   A 1 241 ? 89.298  111.787 76.238  1.00 45.33  ? 241 LEU   A CD1 1 
ATOM   1685 C CD2 . LEU   A 1 241 ? 90.391  109.675 76.973  1.00 45.33  ? 241 LEU   A CD2 1 
ATOM   1686 N N   . ASP   A 1 242 ? 85.140  108.507 77.749  1.00 49.96  ? 242 ASP   A N   1 
ATOM   1687 C CA  . ASP   A 1 242 ? 83.979  108.310 78.609  1.00 49.96  ? 242 ASP   A CA  1 
ATOM   1688 C C   . ASP   A 1 242 ? 83.873  106.862 79.058  1.00 49.96  ? 242 ASP   A C   1 
ATOM   1689 O O   . ASP   A 1 242 ? 83.463  106.581 80.190  1.00 49.96  ? 242 ASP   A O   1 
ATOM   1690 C CB  . ASP   A 1 242 ? 82.708  108.737 77.877  1.00 49.96  ? 242 ASP   A CB  1 
ATOM   1691 C CG  . ASP   A 1 242 ? 81.450  108.421 78.658  1.00 49.96  ? 242 ASP   A CG  1 
ATOM   1692 O OD1 . ASP   A 1 242 ? 81.435  108.660 79.883  1.00 49.96  ? 242 ASP   A OD1 1 
ATOM   1693 O OD2 . ASP   A 1 242 ? 80.478  107.931 78.047  1.00 49.96  ? 242 ASP   A OD2 1 
ATOM   1694 N N   . SER   A 1 243 ? 84.247  105.925 78.185  1.00 44.02  ? 243 SER   A N   1 
ATOM   1695 C CA  . SER   A 1 243 ? 84.309  104.534 78.608  1.00 44.02  ? 243 SER   A CA  1 
ATOM   1696 C C   . SER   A 1 243 ? 85.492  104.301 79.536  1.00 44.02  ? 243 SER   A C   1 
ATOM   1697 O O   . SER   A 1 243 ? 85.356  103.630 80.566  1.00 44.02  ? 243 SER   A O   1 
ATOM   1698 C CB  . SER   A 1 243 ? 84.384  103.621 77.387  1.00 44.02  ? 243 SER   A CB  1 
ATOM   1699 O OG  . SER   A 1 243 ? 84.664  102.287 77.767  1.00 44.02  ? 243 SER   A OG  1 
ATOM   1700 N N   . PHE   A 1 244 ? 86.650  104.884 79.207  1.00 42.09  ? 244 PHE   A N   1 
ATOM   1701 C CA  . PHE   A 1 244 ? 87.881  104.564 79.925  1.00 42.09  ? 244 PHE   A CA  1 
ATOM   1702 C C   . PHE   A 1 244 ? 87.822  105.067 81.362  1.00 42.09  ? 244 PHE   A C   1 
ATOM   1703 O O   . PHE   A 1 244 ? 88.135  104.328 82.303  1.00 42.09  ? 244 PHE   A O   1 
ATOM   1704 C CB  . PHE   A 1 244 ? 89.080  105.153 79.183  1.00 42.09  ? 244 PHE   A CB  1 
ATOM   1705 C CG  . PHE   A 1 244 ? 90.395  104.545 79.570  1.00 42.09  ? 244 PHE   A CG  1 
ATOM   1706 C CD1 . PHE   A 1 244 ? 90.773  103.315 79.061  1.00 42.09  ? 244 PHE   A CD1 1 
ATOM   1707 C CD2 . PHE   A 1 244 ? 91.262  105.204 80.419  1.00 42.09  ? 244 PHE   A CD2 1 
ATOM   1708 C CE1 . PHE   A 1 244 ? 91.980  102.744 79.404  1.00 42.09  ? 244 PHE   A CE1 1 
ATOM   1709 C CE2 . PHE   A 1 244 ? 92.476  104.637 80.763  1.00 42.09  ? 244 PHE   A CE2 1 
ATOM   1710 C CZ  . PHE   A 1 244 ? 92.832  103.407 80.256  1.00 42.09  ? 244 PHE   A CZ  1 
ATOM   1711 N N   . LEU   A 1 245 ? 87.378  106.312 81.550  1.00 40.39  ? 245 LEU   A N   1 
ATOM   1712 C CA  . LEU   A 1 245 ? 87.155  106.837 82.890  1.00 40.39  ? 245 LEU   A CA  1 
ATOM   1713 C C   . LEU   A 1 245 ? 86.081  106.062 83.638  1.00 40.39  ? 245 LEU   A C   1 
ATOM   1714 O O   . LEU   A 1 245 ? 86.059  106.093 84.872  1.00 40.39  ? 245 LEU   A O   1 
ATOM   1715 C CB  . LEU   A 1 245 ? 86.766  108.313 82.822  1.00 40.39  ? 245 LEU   A CB  1 
ATOM   1716 C CG  . LEU   A 1 245 ? 87.837  109.299 82.363  1.00 40.39  ? 245 LEU   A CG  1 
ATOM   1717 C CD1 . LEU   A 1 245 ? 87.253  110.695 82.278  1.00 40.39  ? 245 LEU   A CD1 1 
ATOM   1718 C CD2 . LEU   A 1 245 ? 89.025  109.272 83.305  1.00 40.39  ? 245 LEU   A CD2 1 
ATOM   1719 N N   . LEU   A 1 246 ? 85.183  105.380 82.921  1.00 42.03  ? 246 LEU   A N   1 
ATOM   1720 C CA  . LEU   A 1 246 ? 84.227  104.508 83.591  1.00 42.03  ? 246 LEU   A CA  1 
ATOM   1721 C C   . LEU   A 1 246 ? 84.930  103.317 84.224  1.00 42.03  ? 246 LEU   A C   1 
ATOM   1722 O O   . LEU   A 1 246 ? 84.549  102.871 85.312  1.00 42.03  ? 246 LEU   A O   1 
ATOM   1723 C CB  . LEU   A 1 246 ? 83.154  104.044 82.605  1.00 42.03  ? 246 LEU   A CB  1 
ATOM   1724 C CG  . LEU   A 1 246 ? 81.985  103.232 83.170  1.00 42.03  ? 246 LEU   A CG  1 
ATOM   1725 C CD1 . LEU   A 1 246 ? 80.676  103.724 82.592  1.00 42.03  ? 246 LEU   A CD1 1 
ATOM   1726 C CD2 . LEU   A 1 246 ? 82.157  101.751 82.884  1.00 42.03  ? 246 LEU   A CD2 1 
ATOM   1727 N N   . LEU   A 1 247 ? 85.956  102.789 83.560  1.00 39.08  ? 247 LEU   A N   1 
ATOM   1728 C CA  . LEU   A 1 247 ? 86.643  101.606 84.060  1.00 39.08  ? 247 LEU   A CA  1 
ATOM   1729 C C   . LEU   A 1 247 ? 87.762  101.959 85.030  1.00 39.08  ? 247 LEU   A C   1 
ATOM   1730 O O   . LEU   A 1 247 ? 87.978  101.240 86.011  1.00 39.08  ? 247 LEU   A O   1 
ATOM   1731 C CB  . LEU   A 1 247 ? 87.192  100.793 82.889  1.00 39.08  ? 247 LEU   A CB  1 
ATOM   1732 C CG  . LEU   A 1 247 ? 86.111  100.087 82.068  1.00 39.08  ? 247 LEU   A CG  1 
ATOM   1733 C CD1 . LEU   A 1 247 ? 86.605  99.800  80.665  1.00 39.08  ? 247 LEU   A CD1 1 
ATOM   1734 C CD2 . LEU   A 1 247 ? 85.655  98.813  82.752  1.00 39.08  ? 247 LEU   A CD2 1 
ATOM   1735 N N   . MET   A 1 248 ? 88.482  103.052 84.768  1.00 38.56  ? 248 MET   A N   1 
ATOM   1736 C CA  . MET   A 1 248 ? 89.544  103.482 85.671  1.00 38.56  ? 248 MET   A CA  1 
ATOM   1737 C C   . MET   A 1 248 ? 88.987  103.914 87.022  1.00 38.56  ? 248 MET   A C   1 
ATOM   1738 O O   . MET   A 1 248 ? 89.556  103.585 88.067  1.00 38.56  ? 248 MET   A O   1 
ATOM   1739 C CB  . MET   A 1 248 ? 90.337  104.626 85.041  1.00 38.56  ? 248 MET   A CB  1 
ATOM   1740 C CG  . MET   A 1 248 ? 91.584  105.009 85.813  1.00 38.56  ? 248 MET   A CG  1 
ATOM   1741 S SD  . MET   A 1 248 ? 92.209  106.646 85.393  1.00 38.56  ? 248 MET   A SD  1 
ATOM   1742 C CE  . MET   A 1 248 ? 92.120  106.618 83.614  1.00 38.56  ? 248 MET   A CE  1 
ATOM   1743 N N   . LEU   A 1 249 ? 87.884  104.659 87.023  1.00 39.50  ? 249 LEU   A N   1 
ATOM   1744 C CA  . LEU   A 1 249 ? 87.337  105.193 88.262  1.00 39.50  ? 249 LEU   A CA  1 
ATOM   1745 C C   . LEU   A 1 249 ? 86.263  104.304 88.871  1.00 39.50  ? 249 LEU   A C   1 
ATOM   1746 O O   . LEU   A 1 249 ? 86.036  104.365 90.084  1.00 39.50  ? 249 LEU   A O   1 
ATOM   1747 C CB  . LEU   A 1 249 ? 86.770  106.594 88.024  1.00 39.50  ? 249 LEU   A CB  1 
ATOM   1748 C CG  . LEU   A 1 249 ? 87.777  107.660 87.589  1.00 39.50  ? 249 LEU   A CG  1 
ATOM   1749 C CD1 . LEU   A 1 249 ? 87.094  109.005 87.425  1.00 39.50  ? 249 LEU   A CD1 1 
ATOM   1750 C CD2 . LEU   A 1 249 ? 88.918  107.756 88.584  1.00 39.50  ? 249 LEU   A CD2 1 
ATOM   1751 N N   . GLY   A 1 250 ? 85.592  103.482 88.062  1.00 40.91  ? 250 GLY   A N   1 
ATOM   1752 C CA  . GLY   A 1 250 ? 84.564  102.604 88.589  1.00 40.91  ? 250 GLY   A CA  1 
ATOM   1753 C C   . GLY   A 1 250 ? 85.086  101.377 89.302  1.00 40.91  ? 250 GLY   A C   1 
ATOM   1754 O O   . GLY   A 1 250 ? 84.341  100.757 90.066  1.00 40.91  ? 250 GLY   A O   1 
ATOM   1755 N N   . GLY   A 1 251 ? 86.346  101.010 89.070  1.00 40.90  ? 251 GLY   A N   1 
ATOM   1756 C CA  . GLY   A 1 251 ? 86.918  99.837  89.702  1.00 40.90  ? 251 GLY   A CA  1 
ATOM   1757 C C   . GLY   A 1 251 ? 87.480  100.047 91.087  1.00 40.90  ? 251 GLY   A C   1 
ATOM   1758 O O   . GLY   A 1 251 ? 87.811  99.067  91.761  1.00 40.90  ? 251 GLY   A O   1 
ATOM   1759 N N   . ILE   A 1 252 ? 87.604  101.293 91.526  1.00 43.19  ? 252 ILE   A N   1 
ATOM   1760 C CA  . ILE   A 1 252 ? 88.128  101.608 92.853  1.00 43.19  ? 252 ILE   A CA  1 
ATOM   1761 C C   . ILE   A 1 252 ? 87.172  101.206 93.978  1.00 43.19  ? 252 ILE   A C   1 
ATOM   1762 O O   . ILE   A 1 252 ? 87.606  100.490 94.890  1.00 43.19  ? 252 ILE   A O   1 
ATOM   1763 C CB  . ILE   A 1 252 ? 88.500  103.098 92.954  1.00 43.19  ? 252 ILE   A CB  1 
ATOM   1764 C CG1 . ILE   A 1 252 ? 89.433  103.489 91.809  1.00 43.19  ? 252 ILE   A CG1 1 
ATOM   1765 C CG2 . ILE   A 1 252 ? 89.145  103.395 94.295  1.00 43.19  ? 252 ILE   A CG2 1 
ATOM   1766 C CD1 . ILE   A 1 252 ? 89.852  104.936 91.833  1.00 43.19  ? 252 ILE   A CD1 1 
ATOM   1767 N N   . PRO   A 1 253 ? 85.861  101.601 93.979  1.00 48.08  ? 253 PRO   A N   1 
ATOM   1768 C CA  . PRO   A 1 253 ? 85.085  101.486 95.225  1.00 48.08  ? 253 PRO   A CA  1 
ATOM   1769 C C   . PRO   A 1 253 ? 84.635  100.080 95.603  1.00 48.08  ? 253 PRO   A C   1 
ATOM   1770 O O   . PRO   A 1 253 ? 83.735  99.937  96.434  1.00 48.08  ? 253 PRO   A O   1 
ATOM   1771 C CB  . PRO   A 1 253 ? 83.863  102.378 94.957  1.00 48.08  ? 253 PRO   A CB  1 
ATOM   1772 C CG  . PRO   A 1 253 ? 84.223  103.205 93.781  1.00 48.08  ? 253 PRO   A CG  1 
ATOM   1773 C CD  . PRO   A 1 253 ? 85.057  102.297 92.958  1.00 48.08  ? 253 PRO   A CD  1 
ATOM   1774 N N   . TRP   A 1 254 ? 85.221  99.044  95.011  1.00 50.00  ? 254 TRP   A N   1 
ATOM   1775 C CA  . TRP   A 1 254 ? 84.797  97.682  95.305  1.00 50.00  ? 254 TRP   A CA  1 
ATOM   1776 C C   . TRP   A 1 254 ? 85.189  97.249  96.716  1.00 50.00  ? 254 TRP   A C   1 
ATOM   1777 O O   . TRP   A 1 254 ? 86.223  97.650  97.254  1.00 50.00  ? 254 TRP   A O   1 
ATOM   1778 C CB  . TRP   A 1 254 ? 85.378  96.714  94.282  1.00 50.00  ? 254 TRP   A CB  1 
ATOM   1779 C CG  . TRP   A 1 254 ? 84.745  96.852  92.948  1.00 50.00  ? 254 TRP   A CG  1 
ATOM   1780 C CD1 . TRP   A 1 254 ? 84.887  97.883  92.070  1.00 50.00  ? 254 TRP   A CD1 1 
ATOM   1781 C CD2 . TRP   A 1 254 ? 83.835  95.933  92.346  1.00 50.00  ? 254 TRP   A CD2 1 
ATOM   1782 N NE1 . TRP   A 1 254 ? 84.130  97.655  90.948  1.00 50.00  ? 254 TRP   A NE1 1 
ATOM   1783 C CE2 . TRP   A 1 254 ? 83.473  96.462  91.094  1.00 50.00  ? 254 TRP   A CE2 1 
ATOM   1784 C CE3 . TRP   A 1 254 ? 83.295  94.707  92.742  1.00 50.00  ? 254 TRP   A CE3 1 
ATOM   1785 C CZ2 . TRP   A 1 254 ? 82.599  95.808  90.238  1.00 50.00  ? 254 TRP   A CZ2 1 
ATOM   1786 C CZ3 . TRP   A 1 254 ? 82.430  94.062  91.892  1.00 50.00  ? 254 TRP   A CZ3 1 
ATOM   1787 C CH2 . TRP   A 1 254 ? 82.090  94.611  90.656  1.00 50.00  ? 254 TRP   A CH2 1 
ATOM   1788 N N   . GLN   A 1 255 ? 84.335  96.410  97.309  1.00 63.74  ? 255 GLN   A N   1 
ATOM   1789 C CA  . GLN   A 1 255 ? 84.539  95.948  98.680  1.00 63.74  ? 255 GLN   A CA  1 
ATOM   1790 C C   . GLN   A 1 255 ? 85.737  95.013  98.790  1.00 63.74  ? 255 GLN   A C   1 
ATOM   1791 O O   . GLN   A 1 255 ? 86.456  95.037  99.796  1.00 63.74  ? 255 GLN   A O   1 
ATOM   1792 C CB  . GLN   A 1 255 ? 83.270  95.259  99.186  1.00 63.74  ? 255 GLN   A CB  1 
ATOM   1793 C CG  . GLN   A 1 255 ? 83.399  94.579  100.543 1.00 63.74  ? 255 GLN   A CG  1 
ATOM   1794 C CD  . GLN   A 1 255 ? 83.511  95.562  101.690 1.00 63.74  ? 255 GLN   A CD  1 
ATOM   1795 O OE1 . GLN   A 1 255 ? 82.546  96.242  102.037 1.00 63.74  ? 255 GLN   A OE1 1 
ATOM   1796 N NE2 . GLN   A 1 255 ? 84.692  95.639  102.291 1.00 63.74  ? 255 GLN   A NE2 1 
ATOM   1797 N N   . ALA   A 1 256 ? 85.962  94.179  97.771  1.00 59.54  ? 256 ALA   A N   1 
ATOM   1798 C CA  . ALA   A 1 256 ? 87.033  93.188  97.837  1.00 59.54  ? 256 ALA   A CA  1 
ATOM   1799 C C   . ALA   A 1 256 ? 88.404  93.847  97.926  1.00 59.54  ? 256 ALA   A C   1 
ATOM   1800 O O   . ALA   A 1 256 ? 89.300  93.343  98.612  1.00 59.54  ? 256 ALA   A O   1 
ATOM   1801 C CB  . ALA   A 1 256 ? 86.963  92.260  96.625  1.00 59.54  ? 256 ALA   A CB  1 
ATOM   1802 N N   . TYR   A 1 257 ? 88.589  94.971  97.233  1.00 56.78  ? 257 TYR   A N   1 
ATOM   1803 C CA  . TYR   A 1 257 ? 89.866  95.675  97.286  1.00 56.78  ? 257 TYR   A CA  1 
ATOM   1804 C C   . TYR   A 1 257 ? 90.061  96.368  98.631  1.00 56.78  ? 257 TYR   A C   1 
ATOM   1805 O O   . TYR   A 1 257 ? 91.142  96.297  99.229  1.00 56.78  ? 257 TYR   A O   1 
ATOM   1806 C CB  . TYR   A 1 257 ? 89.948  96.680  96.137  1.00 56.78  ? 257 TYR   A CB  1 
ATOM   1807 C CG  . TYR   A 1 257 ? 91.062  97.691  96.271  1.00 56.78  ? 257 TYR   A CG  1 
ATOM   1808 C CD1 . TYR   A 1 257 ? 92.386  97.318  96.094  1.00 56.78  ? 257 TYR   A CD1 1 
ATOM   1809 C CD2 . TYR   A 1 257 ? 90.789  99.020  96.563  1.00 56.78  ? 257 TYR   A CD2 1 
ATOM   1810 C CE1 . TYR   A 1 257 ? 93.407  98.237  96.211  1.00 56.78  ? 257 TYR   A CE1 1 
ATOM   1811 C CE2 . TYR   A 1 257 ? 91.804  99.945  96.682  1.00 56.78  ? 257 TYR   A CE2 1 
ATOM   1812 C CZ  . TYR   A 1 257 ? 93.110  99.548  96.502  1.00 56.78  ? 257 TYR   A CZ  1 
ATOM   1813 O OH  . TYR   A 1 257 ? 94.127  100.465 96.622  1.00 56.78  ? 257 TYR   A OH  1 
ATOM   1814 N N   . PHE   A 1 258 ? 89.020  97.039  99.129  1.00 58.95  ? 258 PHE   A N   1 
ATOM   1815 C CA  . PHE   A 1 258 ? 89.175  97.788  100.370 1.00 58.95  ? 258 PHE   A CA  1 
ATOM   1816 C C   . PHE   A 1 258 ? 89.285  96.866  101.575 1.00 58.95  ? 258 PHE   A C   1 
ATOM   1817 O O   . PHE   A 1 258 ? 89.899  97.241  102.578 1.00 58.95  ? 258 PHE   A O   1 
ATOM   1818 C CB  . PHE   A 1 258 ? 88.022  98.773  100.551 1.00 58.95  ? 258 PHE   A CB  1 
ATOM   1819 C CG  . PHE   A 1 258 ? 88.172  100.023 99.737  1.00 58.95  ? 258 PHE   A CG  1 
ATOM   1820 C CD1 . PHE   A 1 258 ? 89.092  100.991 100.096 1.00 58.95  ? 258 PHE   A CD1 1 
ATOM   1821 C CD2 . PHE   A 1 258 ? 87.386  100.237 98.622  1.00 58.95  ? 258 PHE   A CD2 1 
ATOM   1822 C CE1 . PHE   A 1 258 ? 89.235  102.138 99.343  1.00 58.95  ? 258 PHE   A CE1 1 
ATOM   1823 C CE2 . PHE   A 1 258 ? 87.521  101.387 97.875  1.00 58.95  ? 258 PHE   A CE2 1 
ATOM   1824 C CZ  . PHE   A 1 258 ? 88.446  102.338 98.237  1.00 58.95  ? 258 PHE   A CZ  1 
ATOM   1825 N N   . GLN   A 1 259 ? 88.722  95.659  101.493 1.00 65.78  ? 259 GLN   A N   1 
ATOM   1826 C CA  . GLN   A 1 259 ? 88.932  94.672  102.547 1.00 65.78  ? 259 GLN   A CA  1 
ATOM   1827 C C   . GLN   A 1 259 ? 90.412  94.349  102.697 1.00 65.78  ? 259 GLN   A C   1 
ATOM   1828 O O   . GLN   A 1 259 ? 90.946  94.311  103.812 1.00 65.78  ? 259 GLN   A O   1 
ATOM   1829 C CB  . GLN   A 1 259 ? 88.134  93.405  102.239 1.00 65.78  ? 259 GLN   A CB  1 
ATOM   1830 C CG  . GLN   A 1 259 ? 88.235  92.333  103.305 1.00 65.78  ? 259 GLN   A CG  1 
ATOM   1831 C CD  . GLN   A 1 259 ? 88.289  90.937  102.718 1.00 65.78  ? 259 GLN   A CD  1 
ATOM   1832 O OE1 . GLN   A 1 259 ? 87.721  90.675  101.657 1.00 65.78  ? 259 GLN   A OE1 1 
ATOM   1833 N NE2 . GLN   A 1 259 ? 88.979  90.033  103.402 1.00 65.78  ? 259 GLN   A NE2 1 
ATOM   1834 N N   . ARG   A 1 260 ? 91.098  94.146  101.572 1.00 65.34  ? 260 ARG   A N   1 
ATOM   1835 C CA  . ARG   A 1 260 ? 92.529  93.873  101.608 1.00 65.34  ? 260 ARG   A CA  1 
ATOM   1836 C C   . ARG   A 1 260 ? 93.322  95.103  102.026 1.00 65.34  ? 260 ARG   A C   1 
ATOM   1837 O O   . ARG   A 1 260 ? 94.365  94.981  102.678 1.00 65.34  ? 260 ARG   A O   1 
ATOM   1838 C CB  . ARG   A 1 260 ? 92.991  93.380  100.242 1.00 65.34  ? 260 ARG   A CB  1 
ATOM   1839 C CG  . ARG   A 1 260 ? 92.362  92.073  99.835  1.00 65.34  ? 260 ARG   A CG  1 
ATOM   1840 C CD  . ARG   A 1 260 ? 92.852  90.959  100.728 1.00 65.34  ? 260 ARG   A CD  1 
ATOM   1841 N NE  . ARG   A 1 260 ? 94.297  90.814  100.628 1.00 65.34  ? 260 ARG   A NE  1 
ATOM   1842 C CZ  . ARG   A 1 260 ? 94.902  90.084  99.705  1.00 65.34  ? 260 ARG   A CZ  1 
ATOM   1843 N NH1 . ARG   A 1 260 ? 94.215  89.460  98.763  1.00 65.34  ? 260 ARG   A NH1 1 
ATOM   1844 N NH2 . ARG   A 1 260 ? 96.229  89.990  99.718  1.00 65.34  ? 260 ARG   A NH2 1 
ATOM   1845 N N   . VAL   A 1 261 ? 92.857  96.293  101.639 1.00 63.36  ? 261 VAL   A N   1 
ATOM   1846 C CA  . VAL   A 1 261 ? 93.556  97.523  102.014 1.00 63.36  ? 261 VAL   A CA  1 
ATOM   1847 C C   . VAL   A 1 261 ? 93.519  97.725  103.525 1.00 63.36  ? 261 VAL   A C   1 
ATOM   1848 O O   . VAL   A 1 261 ? 94.547  97.993  104.158 1.00 63.36  ? 261 VAL   A O   1 
ATOM   1849 C CB  . VAL   A 1 261 ? 92.958  98.728  101.268 1.00 63.36  ? 261 VAL   A CB  1 
ATOM   1850 C CG1 . VAL   A 1 261 ? 93.469  100.026 101.862 1.00 63.36  ? 261 VAL   A CG1 1 
ATOM   1851 C CG2 . VAL   A 1 261 ? 93.320  98.657  99.809  1.00 63.36  ? 261 VAL   A CG2 1 
ATOM   1852 N N   . LEU   A 1 262 ? 92.338  97.589  104.128 1.00 70.84  ? 262 LEU   A N   1 
ATOM   1853 C CA  . LEU   A 1 262 ? 92.220  97.747  105.573 1.00 70.84  ? 262 LEU   A CA  1 
ATOM   1854 C C   . LEU   A 1 262 ? 92.754  96.549  106.347 1.00 70.84  ? 262 LEU   A C   1 
ATOM   1855 O O   . LEU   A 1 262 ? 93.051  96.686  107.539 1.00 70.84  ? 262 LEU   A O   1 
ATOM   1856 C CB  . LEU   A 1 262 ? 90.765  98.022  105.960 1.00 70.84  ? 262 LEU   A CB  1 
ATOM   1857 C CG  . LEU   A 1 262 ? 90.069  99.088  105.110 1.00 70.84  ? 262 LEU   A CG  1 
ATOM   1858 C CD1 . LEU   A 1 262 ? 88.585  99.168  105.416 1.00 70.84  ? 262 LEU   A CD1 1 
ATOM   1859 C CD2 . LEU   A 1 262 ? 90.734  100.440 105.311 1.00 70.84  ? 262 LEU   A CD2 1 
ATOM   1860 N N   . SER   A 1 263 ? 92.887  95.385  105.707 1.00 70.92  ? 263 SER   A N   1 
ATOM   1861 C CA  . SER   A 1 263 ? 93.507  94.244  106.371 1.00 70.92  ? 263 SER   A CA  1 
ATOM   1862 C C   . SER   A 1 263 ? 95.015  94.407  106.520 1.00 70.92  ? 263 SER   A C   1 
ATOM   1863 O O   . SER   A 1 263 ? 95.618  93.720  107.351 1.00 70.92  ? 263 SER   A O   1 
ATOM   1864 C CB  . SER   A 1 263 ? 93.199  92.957  105.606 1.00 70.92  ? 263 SER   A CB  1 
ATOM   1865 O OG  . SER   A 1 263 ? 91.809  92.683  105.602 1.00 70.92  ? 263 SER   A OG  1 
ATOM   1866 N N   . SER   A 1 264 ? 95.631  95.286  105.734 1.00 72.14  ? 264 SER   A N   1 
ATOM   1867 C CA  . SER   A 1 264 ? 97.076  95.463  105.771 1.00 72.14  ? 264 SER   A CA  1 
ATOM   1868 C C   . SER   A 1 264 ? 97.520  96.102  107.083 1.00 72.14  ? 264 SER   A C   1 
ATOM   1869 O O   . SER   A 1 264 ? 96.760  96.814  107.745 1.00 72.14  ? 264 SER   A O   1 
ATOM   1870 C CB  . SER   A 1 264 ? 97.537  96.319  104.595 1.00 72.14  ? 264 SER   A CB  1 
ATOM   1871 O OG  . SER   A 1 264 ? 97.366  95.627  103.372 1.00 72.14  ? 264 SER   A OG  1 
ATOM   1872 N N   . SER   A 1 265 ? 98.773  95.830  107.456 1.00 76.59  ? 265 SER   A N   1 
ATOM   1873 C CA  . SER   A 1 265 ? 99.301  96.313  108.728 1.00 76.59  ? 265 SER   A CA  1 
ATOM   1874 C C   . SER   A 1 265 ? 99.493  97.825  108.719 1.00 76.59  ? 265 SER   A C   1 
ATOM   1875 O O   . SER   A 1 265 ? 99.069  98.520  109.650 1.00 76.59  ? 265 SER   A O   1 
ATOM   1876 C CB  . SER   A 1 265 ? 100.619 95.607  109.046 1.00 76.59  ? 265 SER   A CB  1 
ATOM   1877 O OG  . SER   A 1 265 ? 101.591 95.878  108.052 1.00 76.59  ? 265 SER   A OG  1 
ATOM   1878 N N   . SER   A 1 266 ? 100.129 98.354  107.676 1.00 76.92  ? 266 SER   A N   1 
ATOM   1879 C CA  . SER   A 1 266 ? 100.426 99.776  107.585 1.00 76.92  ? 266 SER   A CA  1 
ATOM   1880 C C   . SER   A 1 266 ? 99.950  100.317 106.245 1.00 76.92  ? 266 SER   A C   1 
ATOM   1881 O O   . SER   A 1 266 ? 99.741  99.568  105.287 1.00 76.92  ? 266 SER   A O   1 
ATOM   1882 C CB  . SER   A 1 266 ? 101.925 100.053 107.768 1.00 76.92  ? 266 SER   A CB  1 
ATOM   1883 O OG  . SER   A 1 266 ? 102.666 99.635  106.637 1.00 76.92  ? 266 SER   A OG  1 
ATOM   1884 N N   . ALA   A 1 267 ? 99.767  101.641 106.199 1.00 73.03  ? 267 ALA   A N   1 
ATOM   1885 C CA  . ALA   A 1 267 ? 99.286  102.291 104.983 1.00 73.03  ? 267 ALA   A CA  1 
ATOM   1886 C C   . ALA   A 1 267 ? 100.278 102.141 103.836 1.00 73.03  ? 267 ALA   A C   1 
ATOM   1887 O O   . ALA   A 1 267 ? 99.880  101.879 102.694 1.00 73.03  ? 267 ALA   A O   1 
ATOM   1888 C CB  . ALA   A 1 267 ? 99.002  103.767 105.256 1.00 73.03  ? 267 ALA   A CB  1 
ATOM   1889 N N   . THR   A 1 268 ? 101.573 102.305 104.121 1.00 71.85  ? 268 THR   A N   1 
ATOM   1890 C CA  . THR   A 1 268 ? 102.594 102.135 103.090 1.00 71.85  ? 268 THR   A CA  1 
ATOM   1891 C C   . THR   A 1 268 ? 102.610 100.704 102.567 1.00 71.85  ? 268 THR   A C   1 
ATOM   1892 O O   . THR   A 1 268 ? 102.782 100.474 101.364 1.00 71.85  ? 268 THR   A O   1 
ATOM   1893 C CB  . THR   A 1 268 ? 103.966 102.522 103.645 1.00 71.85  ? 268 THR   A CB  1 
ATOM   1894 O OG1 . THR   A 1 268 ? 103.906 103.847 104.187 1.00 71.85  ? 268 THR   A OG1 1 
ATOM   1895 C CG2 . THR   A 1 268 ? 105.022 102.482 102.551 1.00 71.85  ? 268 THR   A CG2 1 
ATOM   1896 N N   . TYR   A 1 269 ? 102.421 99.732  103.462 1.00 69.27  ? 269 TYR   A N   1 
ATOM   1897 C CA  . TYR   A 1 269 ? 102.321 98.336  103.049 1.00 69.27  ? 269 TYR   A CA  1 
ATOM   1898 C C   . TYR   A 1 269 ? 101.138 98.129  102.112 1.00 69.27  ? 269 TYR   A C   1 
ATOM   1899 O O   . TYR   A 1 269 ? 101.248 97.413  101.109 1.00 69.27  ? 269 TYR   A O   1 
ATOM   1900 C CB  . TYR   A 1 269 ? 102.197 97.449  104.288 1.00 69.27  ? 269 TYR   A CB  1 
ATOM   1901 C CG  . TYR   A 1 269 ? 102.253 95.962  104.032 1.00 69.27  ? 269 TYR   A CG  1 
ATOM   1902 C CD1 . TYR   A 1 269 ? 103.421 95.353  103.598 1.00 69.27  ? 269 TYR   A CD1 1 
ATOM   1903 C CD2 . TYR   A 1 269 ? 101.140 95.162  104.249 1.00 69.27  ? 269 TYR   A CD2 1 
ATOM   1904 C CE1 . TYR   A 1 269 ? 103.475 93.992  103.378 1.00 69.27  ? 269 TYR   A CE1 1 
ATOM   1905 C CE2 . TYR   A 1 269 ? 101.184 93.801  104.031 1.00 69.27  ? 269 TYR   A CE2 1 
ATOM   1906 C CZ  . TYR   A 1 269 ? 102.352 93.222  103.593 1.00 69.27  ? 269 TYR   A CZ  1 
ATOM   1907 O OH  . TYR   A 1 269 ? 102.396 91.865  103.374 1.00 69.27  ? 269 TYR   A OH  1 
ATOM   1908 N N   . ALA   A 1 270 ? 100.002 98.766  102.415 1.00 65.11  ? 270 ALA   A N   1 
ATOM   1909 C CA  . ALA   A 1 270 ? 98.835  98.682  101.543 1.00 65.11  ? 270 ALA   A CA  1 
ATOM   1910 C C   . ALA   A 1 270 ? 99.110  99.302  100.178 1.00 65.11  ? 270 ALA   A C   1 
ATOM   1911 O O   . ALA   A 1 270 ? 98.687  98.762  99.149  1.00 65.11  ? 270 ALA   A O   1 
ATOM   1912 C CB  . ALA   A 1 270 ? 97.637  99.360  102.206 1.00 65.11  ? 270 ALA   A CB  1 
ATOM   1913 N N   . GLN   A 1 271 ? 99.816  100.437 100.150 1.00 58.74  ? 271 GLN   A N   1 
ATOM   1914 C CA  . GLN   A 1 271 ? 100.159 101.065 98.875  1.00 58.74  ? 271 GLN   A CA  1 
ATOM   1915 C C   . GLN   A 1 271 ? 101.064 100.169 98.039  1.00 58.74  ? 271 GLN   A C   1 
ATOM   1916 O O   . GLN   A 1 271 ? 100.877 100.043 96.821  1.00 58.74  ? 271 GLN   A O   1 
ATOM   1917 C CB  . GLN   A 1 271 ? 100.830 102.417 99.115  1.00 58.74  ? 271 GLN   A CB  1 
ATOM   1918 C CG  . GLN   A 1 271 ? 99.985  103.408 99.891  1.00 58.74  ? 271 GLN   A CG  1 
ATOM   1919 C CD  . GLN   A 1 271 ? 100.548 104.812 99.849  1.00 58.74  ? 271 GLN   A CD  1 
ATOM   1920 O OE1 . GLN   A 1 271 ? 101.428 105.116 99.045  1.00 58.74  ? 271 GLN   A OE1 1 
ATOM   1921 N NE2 . GLN   A 1 271 ? 100.044 105.677 100.720 1.00 58.74  ? 271 GLN   A NE2 1 
ATOM   1922 N N   . VAL   A 1 272 ? 102.050 99.534  98.677  1.00 56.58  ? 272 VAL   A N   1 
ATOM   1923 C CA  . VAL   A 1 272 ? 102.962 98.661  97.943  1.00 56.58  ? 272 VAL   A CA  1 
ATOM   1924 C C   . VAL   A 1 272 ? 102.229 97.425  97.433  1.00 56.58  ? 272 VAL   A C   1 
ATOM   1925 O O   . VAL   A 1 272 ? 102.470 96.968  96.308  1.00 56.58  ? 272 VAL   A O   1 
ATOM   1926 C CB  . VAL   A 1 272 ? 104.179 98.296  98.814  1.00 56.58  ? 272 VAL   A CB  1 
ATOM   1927 C CG1 . VAL   A 1 272 ? 105.115 97.368  98.064  1.00 56.58  ? 272 VAL   A CG1 1 
ATOM   1928 C CG2 . VAL   A 1 272 ? 104.931 99.551  99.206  1.00 56.58  ? 272 VAL   A CG2 1 
ATOM   1929 N N   . LEU   A 1 273 ? 101.311 96.873  98.237  1.00 57.14  ? 273 LEU   A N   1 
ATOM   1930 C CA  . LEU   A 1 273 ? 100.501 95.754  97.759  1.00 57.14  ? 273 LEU   A CA  1 
ATOM   1931 C C   . LEU   A 1 273 ? 99.626  96.164  96.583  1.00 57.14  ? 273 LEU   A C   1 
ATOM   1932 O O   . LEU   A 1 273 ? 99.439  95.384  95.645  1.00 57.14  ? 273 LEU   A O   1 
ATOM   1933 C CB  . LEU   A 1 273 ? 99.631  95.186  98.878  1.00 57.14  ? 273 LEU   A CB  1 
ATOM   1934 C CG  . LEU   A 1 273 ? 100.289 94.502  100.071 1.00 57.14  ? 273 LEU   A CG  1 
ATOM   1935 C CD1 . LEU   A 1 273 ? 99.225  94.154  101.093 1.00 57.14  ? 273 LEU   A CD1 1 
ATOM   1936 C CD2 . LEU   A 1 273 ? 101.040 93.265  99.629  1.00 57.14  ? 273 LEU   A CD2 1 
ATOM   1937 N N   . SER   A 1 274 ? 99.076  97.380  96.620  1.00 50.30  ? 274 SER   A N   1 
ATOM   1938 C CA  . SER   A 1 274 ? 98.256  97.861  95.511  1.00 50.30  ? 274 SER   A CA  1 
ATOM   1939 C C   . SER   A 1 274 ? 99.076  98.001  94.234  1.00 50.30  ? 274 SER   A C   1 
ATOM   1940 O O   . SER   A 1 274 ? 98.628  97.608  93.149  1.00 50.30  ? 274 SER   A O   1 
ATOM   1941 C CB  . SER   A 1 274 ? 97.607  99.190  95.885  1.00 50.30  ? 274 SER   A CB  1 
ATOM   1942 O OG  . SER   A 1 274 ? 96.721  99.029  96.976  1.00 50.30  ? 274 SER   A OG  1 
ATOM   1943 N N   . PHE   A 1 275 ? 100.285 98.561  94.342  1.00 48.62  ? 275 PHE   A N   1 
ATOM   1944 C CA  . PHE   A 1 275 ? 101.141 98.695  93.164  1.00 48.62  ? 275 PHE   A CA  1 
ATOM   1945 C C   . PHE   A 1 275 ? 101.562 97.334  92.619  1.00 48.62  ? 275 PHE   A C   1 
ATOM   1946 O O   . PHE   A 1 275 ? 101.587 97.128  91.398  1.00 48.62  ? 275 PHE   A O   1 
ATOM   1947 C CB  . PHE   A 1 275 ? 102.369 99.545  93.486  1.00 48.62  ? 275 PHE   A CB  1 
ATOM   1948 C CG  . PHE   A 1 275 ? 102.044 100.956 93.877  1.00 48.62  ? 275 PHE   A CG  1 
ATOM   1949 C CD1 . PHE   A 1 275 ? 101.018 101.641 93.252  1.00 48.62  ? 275 PHE   A CD1 1 
ATOM   1950 C CD2 . PHE   A 1 275 ? 102.774 101.604 94.859  1.00 48.62  ? 275 PHE   A CD2 1 
ATOM   1951 C CE1 . PHE   A 1 275 ? 100.717 102.941 93.608  1.00 48.62  ? 275 PHE   A CE1 1 
ATOM   1952 C CE2 . PHE   A 1 275 ? 102.477 102.905 95.219  1.00 48.62  ? 275 PHE   A CE2 1 
ATOM   1953 C CZ  . PHE   A 1 275 ? 101.447 103.574 94.590  1.00 48.62  ? 275 PHE   A CZ  1 
ATOM   1954 N N   . LEU   A 1 276 ? 101.889 96.389  93.507  1.00 48.50  ? 276 LEU   A N   1 
ATOM   1955 C CA  . LEU   A 1 276 ? 102.256 95.050  93.057  1.00 48.50  ? 276 LEU   A CA  1 
ATOM   1956 C C   . LEU   A 1 276 ? 101.071 94.335  92.419  1.00 48.50  ? 276 LEU   A C   1 
ATOM   1957 O O   . LEU   A 1 276 ? 101.241 93.593  91.447  1.00 48.50  ? 276 LEU   A O   1 
ATOM   1958 C CB  . LEU   A 1 276 ? 102.811 94.233  94.223  1.00 48.50  ? 276 LEU   A CB  1 
ATOM   1959 C CG  . LEU   A 1 276 ? 104.200 94.621  94.733  1.00 48.50  ? 276 LEU   A CG  1 
ATOM   1960 C CD1 . LEU   A 1 276 ? 104.556 93.824  95.975  1.00 48.50  ? 276 LEU   A CD1 1 
ATOM   1961 C CD2 . LEU   A 1 276 ? 105.247 94.423  93.651  1.00 48.50  ? 276 LEU   A CD2 1 
ATOM   1962 N N   . ALA   A 1 277 ? 99.864  94.547  92.948  1.00 45.09  ? 277 ALA   A N   1 
ATOM   1963 C CA  . ALA   A 1 277 ? 98.673  93.955  92.351  1.00 45.09  ? 277 ALA   A CA  1 
ATOM   1964 C C   . ALA   A 1 277 ? 98.391  94.543  90.977  1.00 45.09  ? 277 ALA   A C   1 
ATOM   1965 O O   . ALA   A 1 277 ? 97.980  93.822  90.062  1.00 45.09  ? 277 ALA   A O   1 
ATOM   1966 C CB  . ALA   A 1 277 ? 97.472  94.152  93.273  1.00 45.09  ? 277 ALA   A CB  1 
ATOM   1967 N N   . ALA   A 1 278 ? 98.594  95.853  90.816  1.00 41.14  ? 278 ALA   A N   1 
ATOM   1968 C CA  . ALA   A 1 278 ? 98.428  96.470  89.504  1.00 41.14  ? 278 ALA   A CA  1 
ATOM   1969 C C   . ALA   A 1 278 ? 99.446  95.933  88.507  1.00 41.14  ? 278 ALA   A C   1 
ATOM   1970 O O   . ALA   A 1 278 ? 99.111  95.666  87.346  1.00 41.14  ? 278 ALA   A O   1 
ATOM   1971 C CB  . ALA   A 1 278 ? 98.542  97.985  89.621  1.00 41.14  ? 278 ALA   A CB  1 
ATOM   1972 N N   . PHE   A 1 279 ? 100.696 95.762  88.946  1.00 42.47  ? 279 PHE   A N   1 
ATOM   1973 C CA  . PHE   A 1 279 ? 101.711 95.177  88.074  1.00 42.47  ? 279 PHE   A CA  1 
ATOM   1974 C C   . PHE   A 1 279 ? 101.356 93.743  87.701  1.00 42.47  ? 279 PHE   A C   1 
ATOM   1975 O O   . PHE   A 1 279 ? 101.530 93.332  86.548  1.00 42.47  ? 279 PHE   A O   1 
ATOM   1976 C CB  . PHE   A 1 279 ? 103.080 95.234  88.749  1.00 42.47  ? 279 PHE   A CB  1 
ATOM   1977 C CG  . PHE   A 1 279 ? 104.165 94.550  87.972  1.00 42.47  ? 279 PHE   A CG  1 
ATOM   1978 C CD1 . PHE   A 1 279 ? 104.674 95.123  86.820  1.00 42.47  ? 279 PHE   A CD1 1 
ATOM   1979 C CD2 . PHE   A 1 279 ? 104.677 93.333  88.391  1.00 42.47  ? 279 PHE   A CD2 1 
ATOM   1980 C CE1 . PHE   A 1 279 ? 105.671 94.497  86.100  1.00 42.47  ? 279 PHE   A CE1 1 
ATOM   1981 C CE2 . PHE   A 1 279 ? 105.675 92.702  87.675  1.00 42.47  ? 279 PHE   A CE2 1 
ATOM   1982 C CZ  . PHE   A 1 279 ? 106.173 93.285  86.529  1.00 42.47  ? 279 PHE   A CZ  1 
ATOM   1983 N N   . GLY   A 1 280 ? 100.852 92.969  88.663  1.00 44.09  ? 280 GLY   A N   1 
ATOM   1984 C CA  . GLY   A 1 280 ? 100.446 91.605  88.371  1.00 44.09  ? 280 GLY   A CA  1 
ATOM   1985 C C   . GLY   A 1 280 ? 99.279  91.534  87.406  1.00 44.09  ? 280 GLY   A C   1 
ATOM   1986 O O   . GLY   A 1 280 ? 99.244  90.669  86.530  1.00 44.09  ? 280 GLY   A O   1 
ATOM   1987 N N   . CYS   A 1 281 ? 98.311  92.441  87.554  1.00 42.16  ? 281 CYS   A N   1 
ATOM   1988 C CA  . CYS   A 1 281 ? 97.199  92.506  86.610  1.00 42.16  ? 281 CYS   A CA  1 
ATOM   1989 C C   . CYS   A 1 281 ? 97.686  92.859  85.211  1.00 42.16  ? 281 CYS   A C   1 
ATOM   1990 O O   . CYS   A 1 281 ? 97.221  92.283  84.219  1.00 42.16  ? 281 CYS   A O   1 
ATOM   1991 C CB  . CYS   A 1 281 ? 96.164  93.523  87.089  1.00 42.16  ? 281 CYS   A CB  1 
ATOM   1992 S SG  . CYS   A 1 281 ? 95.167  92.977  88.489  1.00 42.16  ? 281 CYS   A SG  1 
ATOM   1993 N N   . LEU   A 1 282 ? 98.632  93.799  85.114  1.00 40.81  ? 282 LEU   A N   1 
ATOM   1994 C CA  . LEU   A 1 282 ? 99.192  94.155  83.813  1.00 40.81  ? 282 LEU   A CA  1 
ATOM   1995 C C   . LEU   A 1 282 ? 99.927  92.980  83.180  1.00 40.81  ? 282 LEU   A C   1 
ATOM   1996 O O   . LEU   A 1 282 ? 99.834  92.766  81.966  1.00 40.81  ? 282 LEU   A O   1 
ATOM   1997 C CB  . LEU   A 1 282 ? 100.125 95.357  83.950  1.00 40.81  ? 282 LEU   A CB  1 
ATOM   1998 C CG  . LEU   A 1 282 ? 99.446  96.725  83.986  1.00 40.81  ? 282 LEU   A CG  1 
ATOM   1999 C CD1 . LEU   A 1 282 ? 100.373 97.776  84.577  1.00 40.81  ? 282 LEU   A CD1 1 
ATOM   2000 C CD2 . LEU   A 1 282 ? 98.988  97.123  82.594  1.00 40.81  ? 282 LEU   A CD2 1 
ATOM   2001 N N   . VAL   A 1 283 ? 100.675 92.216  83.981  1.00 41.61  ? 283 VAL   A N   1 
ATOM   2002 C CA  . VAL   A 1 283 ? 101.375 91.048  83.448  1.00 41.61  ? 283 VAL   A CA  1 
ATOM   2003 C C   . VAL   A 1 283 ? 100.383 89.977  83.007  1.00 41.61  ? 283 VAL   A C   1 
ATOM   2004 O O   . VAL   A 1 283 ? 100.533 89.380  81.935  1.00 41.61  ? 283 VAL   A O   1 
ATOM   2005 C CB  . VAL   A 1 283 ? 102.383 90.498  84.475  1.00 41.61  ? 283 VAL   A CB  1 
ATOM   2006 C CG1 . VAL   A 1 283 ? 103.022 89.224  83.958  1.00 41.61  ? 283 VAL   A CG1 1 
ATOM   2007 C CG2 . VAL   A 1 283 ? 103.464 91.522  84.751  1.00 41.61  ? 283 VAL   A CG2 1 
ATOM   2008 N N   . MET   A 1 284 ? 99.347  89.726  83.810  1.00 43.81  ? 284 MET   A N   1 
ATOM   2009 C CA  . MET   A 1 284 ? 98.385  88.679  83.486  1.00 43.81  ? 284 MET   A CA  1 
ATOM   2010 C C   . MET   A 1 284 ? 97.457  89.057  82.343  1.00 43.81  ? 284 MET   A C   1 
ATOM   2011 O O   . MET   A 1 284 ? 96.828  88.170  81.758  1.00 43.81  ? 284 MET   A O   1 
ATOM   2012 C CB  . MET   A 1 284 ? 97.548  88.320  84.715  1.00 43.81  ? 284 MET   A CB  1 
ATOM   2013 C CG  . MET   A 1 284 ? 98.336  87.685  85.841  1.00 43.81  ? 284 MET   A CG  1 
ATOM   2014 S SD  . MET   A 1 284 ? 99.106  86.140  85.336  1.00 43.81  ? 284 MET   A SD  1 
ATOM   2015 C CE  . MET   A 1 284 ? 97.669  85.099  85.142  1.00 43.81  ? 284 MET   A CE  1 
ATOM   2016 N N   . ALA   A 1 285 ? 97.341  90.346  82.021  1.00 39.80  ? 285 ALA   A N   1 
ATOM   2017 C CA  . ALA   A 1 285 ? 96.545  90.738  80.866  1.00 39.80  ? 285 ALA   A CA  1 
ATOM   2018 C C   . ALA   A 1 285 ? 97.210  90.375  79.544  1.00 39.80  ? 285 ALA   A C   1 
ATOM   2019 O O   . ALA   A 1 285 ? 96.510  90.234  78.538  1.00 39.80  ? 285 ALA   A O   1 
ATOM   2020 C CB  . ALA   A 1 285 ? 96.262  92.239  80.905  1.00 39.80  ? 285 ALA   A CB  1 
ATOM   2021 N N   . ILE   A 1 286 ? 98.532  90.226  79.521  1.00 37.94  ? 286 ILE   A N   1 
ATOM   2022 C CA  . ILE   A 1 286 ? 99.278  89.957  78.291  1.00 37.94  ? 286 ILE   A CA  1 
ATOM   2023 C C   . ILE   A 1 286 ? 98.924  88.601  77.674  1.00 37.94  ? 286 ILE   A C   1 
ATOM   2024 O O   . ILE   A 1 286 ? 98.672  88.557  76.459  1.00 37.94  ? 286 ILE   A O   1 
ATOM   2025 C CB  . ILE   A 1 286 ? 100.795 90.097  78.526  1.00 37.94  ? 286 ILE   A CB  1 
ATOM   2026 C CG1 . ILE   A 1 286 ? 101.155 91.552  78.822  1.00 37.94  ? 286 ILE   A CG1 1 
ATOM   2027 C CG2 . ILE   A 1 286 ? 101.581 89.597  77.325  1.00 37.94  ? 286 ILE   A CG2 1 
ATOM   2028 C CD1 . ILE   A 1 286 ? 102.638 91.795  78.962  1.00 37.94  ? 286 ILE   A CD1 1 
ATOM   2029 N N   . PRO   A 1 287 ? 98.895  87.474  78.413  1.00 37.43  ? 287 PRO   A N   1 
ATOM   2030 C CA  . PRO   A 1 287 ? 98.467  86.222  77.761  1.00 37.43  ? 287 PRO   A CA  1 
ATOM   2031 C C   . PRO   A 1 287 ? 97.034  86.249  77.261  1.00 37.43  ? 287 PRO   A C   1 
ATOM   2032 O O   . PRO   A 1 287 ? 96.745  85.642  76.225  1.00 37.43  ? 287 PRO   A O   1 
ATOM   2033 C CB  . PRO   A 1 287 ? 98.657  85.161  78.855  1.00 37.43  ? 287 PRO   A CB  1 
ATOM   2034 C CG  . PRO   A 1 287 ? 98.745  85.900  80.113  1.00 37.43  ? 287 PRO   A CG  1 
ATOM   2035 C CD  . PRO   A 1 287 ? 99.363  87.206  79.787  1.00 37.43  ? 287 PRO   A CD  1 
ATOM   2036 N N   . ALA   A 1 288 ? 96.127  86.940  77.957  1.00 36.33  ? 288 ALA   A N   1 
ATOM   2037 C CA  . ALA   A 1 288 ? 94.750  87.042  77.480  1.00 36.33  ? 288 ALA   A CA  1 
ATOM   2038 C C   . ALA   A 1 288 ? 94.669  87.835  76.181  1.00 36.33  ? 288 ALA   A C   1 
ATOM   2039 O O   . ALA   A 1 288 ? 93.929  87.462  75.262  1.00 36.33  ? 288 ALA   A O   1 
ATOM   2040 C CB  . ALA   A 1 288 ? 93.872  87.675  78.556  1.00 36.33  ? 288 ALA   A CB  1 
ATOM   2041 N N   . ILE   A 1 289 ? 95.432  88.928  76.086  1.00 34.02  ? 289 ILE   A N   1 
ATOM   2042 C CA  . ILE   A 1 289 ? 95.497  89.702  74.849  1.00 34.02  ? 289 ILE   A CA  1 
ATOM   2043 C C   . ILE   A 1 289 ? 96.084  88.857  73.726  1.00 34.02  ? 289 ILE   A C   1 
ATOM   2044 O O   . ILE   A 1 289 ? 95.613  88.903  72.583  1.00 34.02  ? 289 ILE   A O   1 
ATOM   2045 C CB  . ILE   A 1 289 ? 96.303  90.996  75.076  1.00 34.02  ? 289 ILE   A CB  1 
ATOM   2046 C CG1 . ILE   A 1 289 ? 95.515  91.967  75.952  1.00 34.02  ? 289 ILE   A CG1 1 
ATOM   2047 C CG2 . ILE   A 1 289 ? 96.657  91.665  73.758  1.00 34.02  ? 289 ILE   A CG2 1 
ATOM   2048 C CD1 . ILE   A 1 289 ? 96.349  93.089  76.512  1.00 34.02  ? 289 ILE   A CD1 1 
ATOM   2049 N N   . LEU   A 1 290 ? 97.110  88.061  74.036  1.00 34.46  ? 290 LEU   A N   1 
ATOM   2050 C CA  . LEU   A 1 290 ? 97.710  87.198  73.023  1.00 34.46  ? 290 LEU   A CA  1 
ATOM   2051 C C   . LEU   A 1 290 ? 96.728  86.138  72.536  1.00 34.46  ? 290 LEU   A C   1 
ATOM   2052 O O   . LEU   A 1 290 ? 96.670  85.846  71.338  1.00 34.46  ? 290 LEU   A O   1 
ATOM   2053 C CB  . LEU   A 1 290 ? 98.977  86.545  73.571  1.00 34.46  ? 290 LEU   A CB  1 
ATOM   2054 C CG  . LEU   A 1 290 ? 100.227 87.424  73.567  1.00 34.46  ? 290 LEU   A CG  1 
ATOM   2055 C CD1 . LEU   A 1 290 ? 101.422 86.657  74.102  1.00 34.46  ? 290 LEU   A CD1 1 
ATOM   2056 C CD2 . LEU   A 1 290 ? 100.504 87.953  72.171  1.00 34.46  ? 290 LEU   A CD2 1 
ATOM   2057 N N   . ILE   A 1 291 ? 95.948  85.552  73.447  1.00 38.02  ? 291 ILE   A N   1 
ATOM   2058 C CA  . ILE   A 1 291 ? 94.959  84.551  73.052  1.00 38.02  ? 291 ILE   A CA  1 
ATOM   2059 C C   . ILE   A 1 291 ? 93.854  85.183  72.210  1.00 38.02  ? 291 ILE   A C   1 
ATOM   2060 O O   . ILE   A 1 291 ? 93.401  84.596  71.218  1.00 38.02  ? 291 ILE   A O   1 
ATOM   2061 C CB  . ILE   A 1 291 ? 94.398  83.833  74.294  1.00 38.02  ? 291 ILE   A CB  1 
ATOM   2062 C CG1 . ILE   A 1 291 ? 95.493  83.005  74.965  1.00 38.02  ? 291 ILE   A CG1 1 
ATOM   2063 C CG2 . ILE   A 1 291 ? 93.228  82.938  73.930  1.00 38.02  ? 291 ILE   A CG2 1 
ATOM   2064 C CD1 . ILE   A 1 291 ? 95.206  82.678  76.406  1.00 38.02  ? 291 ILE   A CD1 1 
ATOM   2065 N N   . GLY   A 1 292 ? 93.405  86.385  72.584  1.00 35.26  ? 292 GLY   A N   1 
ATOM   2066 C CA  . GLY   A 1 292 ? 92.428  87.085  71.762  1.00 35.26  ? 292 GLY   A CA  1 
ATOM   2067 C C   . GLY   A 1 292 ? 92.951  87.400  70.372  1.00 35.26  ? 292 GLY   A C   1 
ATOM   2068 O O   . GLY   A 1 292 ? 92.235  87.248  69.379  1.00 35.26  ? 292 GLY   A O   1 
ATOM   2069 N N   . ALA   A 1 293 ? 94.214  87.823  70.284  1.00 38.28  ? 293 ALA   A N   1 
ATOM   2070 C CA  . ALA   A 1 293 ? 94.829  88.093  68.988  1.00 38.28  ? 293 ALA   A CA  1 
ATOM   2071 C C   . ALA   A 1 293 ? 94.982  86.822  68.160  1.00 38.28  ? 293 ALA   A C   1 
ATOM   2072 O O   . ALA   A 1 293 ? 94.812  86.850  66.936  1.00 38.28  ? 293 ALA   A O   1 
ATOM   2073 C CB  . ALA   A 1 293 ? 96.183  88.766  69.190  1.00 38.28  ? 293 ALA   A CB  1 
ATOM   2074 N N   . ILE   A 1 294 ? 95.319  85.703  68.806  1.00 40.37  ? 294 ILE   A N   1 
ATOM   2075 C CA  . ILE   A 1 294 ? 95.430  84.430  68.101  1.00 40.37  ? 294 ILE   A CA  1 
ATOM   2076 C C   . ILE   A 1 294 ? 94.072  84.000  67.561  1.00 40.37  ? 294 ILE   A C   1 
ATOM   2077 O O   . ILE   A 1 294 ? 93.960  83.539  66.419  1.00 40.37  ? 294 ILE   A O   1 
ATOM   2078 C CB  . ILE   A 1 294 ? 96.045  83.361  69.025  1.00 40.37  ? 294 ILE   A CB  1 
ATOM   2079 C CG1 . ILE   A 1 294 ? 97.545  83.596  69.196  1.00 40.37  ? 294 ILE   A CG1 1 
ATOM   2080 C CG2 . ILE   A 1 294 ? 95.817  81.965  68.479  1.00 40.37  ? 294 ILE   A CG2 1 
ATOM   2081 C CD1 . ILE   A 1 294 ? 98.107  83.018  70.475  1.00 40.37  ? 294 ILE   A CD1 1 
ATOM   2082 N N   . GLY   A 1 295 ? 93.020  84.152  68.369  1.00 42.06  ? 295 GLY   A N   1 
ATOM   2083 C CA  . GLY   A 1 295 ? 91.681  83.844  67.892  1.00 42.06  ? 295 GLY   A CA  1 
ATOM   2084 C C   . GLY   A 1 295 ? 91.246  84.742  66.750  1.00 42.06  ? 295 GLY   A C   1 
ATOM   2085 O O   . GLY   A 1 295 ? 90.565  84.297  65.824  1.00 42.06  ? 295 GLY   A O   1 
ATOM   2086 N N   . ALA   A 1 296 ? 91.633  86.018  66.802  1.00 42.80  ? 296 ALA   A N   1 
ATOM   2087 C CA  . ALA   A 1 296 ? 91.351  86.927  65.695  1.00 42.80  ? 296 ALA   A CA  1 
ATOM   2088 C C   . ALA   A 1 296 ? 92.108  86.523  64.435  1.00 42.80  ? 296 ALA   A C   1 
ATOM   2089 O O   . ALA   A 1 296 ? 91.595  86.676  63.321  1.00 42.80  ? 296 ALA   A O   1 
ATOM   2090 C CB  . ALA   A 1 296 ? 91.698  88.360  66.092  1.00 42.80  ? 296 ALA   A CB  1 
ATOM   2091 N N   . SER   A 1 297 ? 93.327  86.011  64.589  1.00 46.24  ? 297 SER   A N   1 
ATOM   2092 C CA  . SER   A 1 297 ? 94.157  85.625  63.456  1.00 46.24  ? 297 SER   A CA  1 
ATOM   2093 C C   . SER   A 1 297 ? 93.921  84.195  62.987  1.00 46.24  ? 297 SER   A C   1 
ATOM   2094 O O   . SER   A 1 297 ? 94.493  83.797  61.967  1.00 46.24  ? 297 SER   A O   1 
ATOM   2095 C CB  . SER   A 1 297 ? 95.636  85.796  63.812  1.00 46.24  ? 297 SER   A CB  1 
ATOM   2096 O OG  . SER   A 1 297 ? 95.942  87.152  64.075  1.00 46.24  ? 297 SER   A OG  1 
ATOM   2097 N N   . THR   A 1 298 ? 93.106  83.420  63.695  1.00 49.19  ? 298 THR   A N   1 
ATOM   2098 C CA  . THR   A 1 298 ? 92.946  82.006  63.381  1.00 49.19  ? 298 THR   A CA  1 
ATOM   2099 C C   . THR   A 1 298 ? 92.087  81.808  62.136  1.00 49.19  ? 298 THR   A C   1 
ATOM   2100 O O   . THR   A 1 298 ? 91.073  82.483  61.946  1.00 49.19  ? 298 THR   A O   1 
ATOM   2101 C CB  . THR   A 1 298 ? 92.318  81.274  64.569  1.00 49.19  ? 298 THR   A CB  1 
ATOM   2102 O OG1 . THR   A 1 298 ? 93.063  81.565  65.757  1.00 49.19  ? 298 THR   A OG1 1 
ATOM   2103 C CG2 . THR   A 1 298 ? 92.318  79.771  64.346  1.00 49.19  ? 298 THR   A CG2 1 
ATOM   2104 N N   . ASP   A 1 299 ? 92.505  80.874  61.284  1.00 57.21  ? 299 ASP   A N   1 
ATOM   2105 C CA  . ASP   A 1 299 ? 91.701  80.400  60.159  1.00 57.21  ? 299 ASP   A CA  1 
ATOM   2106 C C   . ASP   A 1 299 ? 91.012  79.119  60.614  1.00 57.21  ? 299 ASP   A C   1 
ATOM   2107 O O   . ASP   A 1 299 ? 91.635  78.056  60.678  1.00 57.21  ? 299 ASP   A O   1 
ATOM   2108 C CB  . ASP   A 1 299 ? 92.571  80.168  58.929  1.00 57.21  ? 299 ASP   A CB  1 
ATOM   2109 C CG  . ASP   A 1 299 ? 91.815  79.517  57.792  1.00 57.21  ? 299 ASP   A CG  1 
ATOM   2110 O OD1 . ASP   A 1 299 ? 90.629  79.853  57.593  1.00 57.21  ? 299 ASP   A OD1 1 
ATOM   2111 O OD2 . ASP   A 1 299 ? 92.408  78.670  57.093  1.00 57.21  ? 299 ASP   A OD2 1 
ATOM   2112 N N   . TRP   A 1 300 ? 89.719  79.218  60.922  1.00 53.55  ? 300 TRP   A N   1 
ATOM   2113 C CA  . TRP   A 1 300 ? 89.017  78.130  61.591  1.00 53.55  ? 300 TRP   A CA  1 
ATOM   2114 C C   . TRP   A 1 300 ? 88.659  76.974  60.667  1.00 53.55  ? 300 TRP   A C   1 
ATOM   2115 O O   . TRP   A 1 300 ? 88.197  75.939  61.159  1.00 53.55  ? 300 TRP   A O   1 
ATOM   2116 C CB  . TRP   A 1 300 ? 87.755  78.663  62.268  1.00 53.55  ? 300 TRP   A CB  1 
ATOM   2117 C CG  . TRP   A 1 300 ? 88.051  79.640  63.360  1.00 53.55  ? 300 TRP   A CG  1 
ATOM   2118 C CD1 . TRP   A 1 300 ? 87.935  80.994  63.297  1.00 53.55  ? 300 TRP   A CD1 1 
ATOM   2119 C CD2 . TRP   A 1 300 ? 88.543  79.339  64.670  1.00 53.55  ? 300 TRP   A CD2 1 
ATOM   2120 N NE1 . TRP   A 1 300 ? 88.307  81.558  64.492  1.00 53.55  ? 300 TRP   A NE1 1 
ATOM   2121 C CE2 . TRP   A 1 300 ? 88.687  80.562  65.352  1.00 53.55  ? 300 TRP   A CE2 1 
ATOM   2122 C CE3 . TRP   A 1 300 ? 88.868  78.154  65.335  1.00 53.55  ? 300 TRP   A CE3 1 
ATOM   2123 C CZ2 . TRP   A 1 300 ? 89.142  80.635  66.665  1.00 53.55  ? 300 TRP   A CZ2 1 
ATOM   2124 C CZ3 . TRP   A 1 300 ? 89.320  78.229  66.638  1.00 53.55  ? 300 TRP   A CZ3 1 
ATOM   2125 C CH2 . TRP   A 1 300 ? 89.454  79.461  67.289  1.00 53.55  ? 300 TRP   A CH2 1 
ATOM   2126 N N   . ASN   A 1 301 ? 88.848  77.119  59.354  1.00 66.59  ? 301 ASN   A N   1 
ATOM   2127 C CA  . ASN   A 1 301 ? 88.632  75.991  58.453  1.00 66.59  ? 301 ASN   A CA  1 
ATOM   2128 C C   . ASN   A 1 301 ? 89.674  74.902  58.676  1.00 66.59  ? 301 ASN   A C   1 
ATOM   2129 O O   . ASN   A 1 301 ? 89.364  73.709  58.582  1.00 66.59  ? 301 ASN   A O   1 
ATOM   2130 C CB  . ASN   A 1 301 ? 88.655  76.464  57.000  1.00 66.59  ? 301 ASN   A CB  1 
ATOM   2131 C CG  . ASN   A 1 301 ? 87.984  75.482  56.059  1.00 66.59  ? 301 ASN   A CG  1 
ATOM   2132 O OD1 . ASN   A 1 301 ? 86.902  74.972  56.346  1.00 66.59  ? 301 ASN   A OD1 1 
ATOM   2133 N ND2 . ASN   A 1 301 ? 88.628  75.208  54.930  1.00 66.59  ? 301 ASN   A ND2 1 
ATOM   2134 N N   . GLN   A 1 302 ? 90.918  75.297  58.961  1.00 70.20  ? 302 GLN   A N   1 
ATOM   2135 C CA  . GLN   A 1 302 ? 91.983  74.324  59.177  1.00 70.20  ? 302 GLN   A CA  1 
ATOM   2136 C C   . GLN   A 1 302 ? 91.783  73.540  60.467  1.00 70.20  ? 302 GLN   A C   1 
ATOM   2137 O O   . GLN   A 1 302 ? 92.204  72.381  60.557  1.00 70.20  ? 302 GLN   A O   1 
ATOM   2138 C CB  . GLN   A 1 302 ? 93.337  75.032  59.199  1.00 70.20  ? 302 GLN   A CB  1 
ATOM   2139 C CG  . GLN   A 1 302 ? 93.739  75.654  57.874  1.00 70.20  ? 302 GLN   A CG  1 
ATOM   2140 C CD  . GLN   A 1 302 ? 93.845  74.636  56.759  1.00 70.20  ? 302 GLN   A CD  1 
ATOM   2141 O OE1 . GLN   A 1 302 ? 94.336  73.525  56.961  1.00 70.20  ? 302 GLN   A OE1 1 
ATOM   2142 N NE2 . GLN   A 1 302 ? 93.375  75.006  55.573  1.00 70.20  ? 302 GLN   A NE2 1 
ATOM   2143 N N   . THR   A 1 303 ? 91.150  74.145  61.468  1.00 62.02  ? 303 THR   A N   1 
ATOM   2144 C CA  . THR   A 1 303 ? 91.011  73.523  62.774  1.00 62.02  ? 303 THR   A CA  1 
ATOM   2145 C C   . THR   A 1 303 ? 89.872  72.506  62.767  1.00 62.02  ? 303 THR   A C   1 
ATOM   2146 O O   . THR   A 1 303 ? 89.206  72.276  61.754  1.00 62.02  ? 303 THR   A O   1 
ATOM   2147 C CB  . THR   A 1 303 ? 90.769  74.584  63.842  1.00 62.02  ? 303 THR   A CB  1 
ATOM   2148 O OG1 . THR   A 1 303 ? 89.551  75.279  63.557  1.00 62.02  ? 303 THR   A OG1 1 
ATOM   2149 C CG2 . THR   A 1 303 ? 91.896  75.582  63.838  1.00 62.02  ? 303 THR   A CG2 1 
ATOM   2150 N N   . ALA   A 1 304 ? 89.650  71.882  63.921  1.00 60.47  ? 304 ALA   A N   1 
ATOM   2151 C CA  . ALA   A 1 304 ? 88.530  70.972  64.101  1.00 60.47  ? 304 ALA   A CA  1 
ATOM   2152 C C   . ALA   A 1 304 ? 87.244  71.690  64.482  1.00 60.47  ? 304 ALA   A C   1 
ATOM   2153 O O   . ALA   A 1 304 ? 86.180  71.060  64.491  1.00 60.47  ? 304 ALA   A O   1 
ATOM   2154 C CB  . ALA   A 1 304 ? 88.866  69.923  65.165  1.00 60.47  ? 304 ALA   A CB  1 
ATOM   2155 N N   . TYR   A 1 305 ? 87.320  72.983  64.806  1.00 56.89  ? 305 TYR   A N   1 
ATOM   2156 C CA  . TYR   A 1 305 ? 86.121  73.748  65.132  1.00 56.89  ? 305 TYR   A CA  1 
ATOM   2157 C C   . TYR   A 1 305 ? 85.217  73.893  63.914  1.00 56.89  ? 305 TYR   A C   1 
ATOM   2158 O O   . TYR   A 1 305 ? 84.001  73.691  63.999  1.00 56.89  ? 305 TYR   A O   1 
ATOM   2159 C CB  . TYR   A 1 305 ? 86.519  75.117  65.683  1.00 56.89  ? 305 TYR   A CB  1 
ATOM   2160 C CG  . TYR   A 1 305 ? 85.418  75.838  66.420  1.00 56.89  ? 305 TYR   A CG  1 
ATOM   2161 C CD1 . TYR   A 1 305 ? 85.170  75.577  67.760  1.00 56.89  ? 305 TYR   A CD1 1 
ATOM   2162 C CD2 . TYR   A 1 305 ? 84.632  76.781  65.781  1.00 56.89  ? 305 TYR   A CD2 1 
ATOM   2163 C CE1 . TYR   A 1 305 ? 84.167  76.236  68.441  1.00 56.89  ? 305 TYR   A CE1 1 
ATOM   2164 C CE2 . TYR   A 1 305 ? 83.627  77.444  66.452  1.00 56.89  ? 305 TYR   A CE2 1 
ATOM   2165 C CZ  . TYR   A 1 305 ? 83.399  77.167  67.781  1.00 56.89  ? 305 TYR   A CZ  1 
ATOM   2166 O OH  . TYR   A 1 305 ? 82.398  77.826  68.453  1.00 56.89  ? 305 TYR   A OH  1 
ATOM   2167 N N   . GLY   A 1 306 ? 85.794  74.251  62.774  1.00 66.01  ? 306 GLY   A N   1 
ATOM   2168 C CA  . GLY   A 1 306 ? 85.057  74.317  61.533  1.00 66.01  ? 306 GLY   A CA  1 
ATOM   2169 C C   . GLY   A 1 306 ? 84.236  75.588  61.400  1.00 66.01  ? 306 GLY   A C   1 
ATOM   2170 O O   . GLY   A 1 306 ? 83.970  76.304  62.364  1.00 66.01  ? 306 GLY   A O   1 
ATOM   2171 N N   . LEU   A 1 307 ? 83.825  75.863  60.165  1.00 72.39  ? 307 LEU   A N   1 
ATOM   2172 C CA  . LEU   A 1 307 ? 82.925  76.979  59.920  1.00 72.39  ? 307 LEU   A CA  1 
ATOM   2173 C C   . LEU   A 1 307 ? 81.516  76.639  60.403  1.00 72.39  ? 307 LEU   A C   1 
ATOM   2174 O O   . LEU   A 1 307 ? 81.076  75.491  60.293  1.00 72.39  ? 307 LEU   A O   1 
ATOM   2175 C CB  . LEU   A 1 307 ? 82.891  77.340  58.435  1.00 72.39  ? 307 LEU   A CB  1 
ATOM   2176 C CG  . LEU   A 1 307 ? 83.972  78.251  57.839  1.00 72.39  ? 307 LEU   A CG  1 
ATOM   2177 C CD1 . LEU   A 1 307 ? 83.892  79.633  58.468  1.00 72.39  ? 307 LEU   A CD1 1 
ATOM   2178 C CD2 . LEU   A 1 307 ? 85.373  77.692  57.983  1.00 72.39  ? 307 LEU   A CD2 1 
ATOM   2179 N N   . PRO   A 1 308 ? 80.778  77.624  60.942  1.00 69.24  ? 308 PRO   A N   1 
ATOM   2180 C CA  . PRO   A 1 308 ? 81.125  79.040  61.116  1.00 69.24  ? 308 PRO   A CA  1 
ATOM   2181 C C   . PRO   A 1 308 ? 82.100  79.307  62.265  1.00 69.24  ? 308 PRO   A C   1 
ATOM   2182 O O   . PRO   A 1 308 ? 82.223  78.483  63.171  1.00 69.24  ? 308 PRO   A O   1 
ATOM   2183 C CB  . PRO   A 1 308 ? 79.769  79.683  61.398  1.00 69.24  ? 308 PRO   A CB  1 
ATOM   2184 C CG  . PRO   A 1 308 ? 79.027  78.623  62.123  1.00 69.24  ? 308 PRO   A CG  1 
ATOM   2185 C CD  . PRO   A 1 308 ? 79.426  77.335  61.451  1.00 69.24  ? 308 PRO   A CD  1 
ATOM   2186 N N   . ASP   A 1 309 ? 82.788  80.447  62.209  1.00 60.86  ? 309 ASP   A N   1 
ATOM   2187 C CA  . ASP   A 1 309 ? 83.720  80.842  63.249  1.00 60.86  ? 309 ASP   A CA  1 
ATOM   2188 C C   . ASP   A 1 309 ? 82.938  81.247  64.500  1.00 60.86  ? 309 ASP   A C   1 
ATOM   2189 O O   . ASP   A 1 309 ? 81.725  81.461  64.431  1.00 60.86  ? 309 ASP   A O   1 
ATOM   2190 C CB  . ASP   A 1 309 ? 84.631  81.959  62.726  1.00 60.86  ? 309 ASP   A CB  1 
ATOM   2191 C CG  . ASP   A 1 309 ? 83.869  83.100  62.088  1.00 60.86  ? 309 ASP   A CG  1 
ATOM   2192 O OD1 . ASP   A 1 309 ? 82.626  83.100  62.130  1.00 60.86  ? 309 ASP   A OD1 1 
ATOM   2193 O OD2 . ASP   A 1 309 ? 84.528  84.006  61.539  1.00 60.86  ? 309 ASP   A OD2 1 
ATOM   2194 N N   . PRO   A 1 310 ? 83.599  81.328  65.671  1.00 53.00  ? 310 PRO   A N   1 
ATOM   2195 C CA  . PRO   A 1 310 ? 82.850  81.606  66.915  1.00 53.00  ? 310 PRO   A CA  1 
ATOM   2196 C C   . PRO   A 1 310 ? 82.050  82.899  66.911  1.00 53.00  ? 310 PRO   A C   1 
ATOM   2197 O O   . PRO   A 1 310 ? 81.034  82.984  67.611  1.00 53.00  ? 310 PRO   A O   1 
ATOM   2198 C CB  . PRO   A 1 310 ? 83.952  81.631  67.981  1.00 53.00  ? 310 PRO   A CB  1 
ATOM   2199 C CG  . PRO   A 1 310 ? 84.989  80.745  67.452  1.00 53.00  ? 310 PRO   A CG  1 
ATOM   2200 C CD  . PRO   A 1 310 ? 84.989  80.933  65.970  1.00 53.00  ? 310 PRO   A CD  1 
ATOM   2201 N N   . LYS   A 1 311 ? 82.481  83.916  66.166  1.00 54.15  ? 311 LYS   A N   1 
ATOM   2202 C CA  . LYS   A 1 311 ? 81.716  85.158  66.127  1.00 54.15  ? 311 LYS   A CA  1 
ATOM   2203 C C   . LYS   A 1 311 ? 80.406  85.004  65.354  1.00 54.15  ? 311 LYS   A C   1 
ATOM   2204 O O   . LYS   A 1 311 ? 79.406  85.636  65.712  1.00 54.15  ? 311 LYS   A O   1 
ATOM   2205 C CB  . LYS   A 1 311 ? 82.588  86.284  65.566  1.00 54.15  ? 311 LYS   A CB  1 
ATOM   2206 C CG  . LYS   A 1 311 ? 82.972  86.150  64.108  1.00 54.15  ? 311 LYS   A CG  1 
ATOM   2207 C CD  . LYS   A 1 311 ? 83.852  87.308  63.676  1.00 54.15  ? 311 LYS   A CD  1 
ATOM   2208 C CE  . LYS   A 1 311 ? 84.279  87.162  62.229  1.00 54.15  ? 311 LYS   A CE  1 
ATOM   2209 N NZ  . LYS   A 1 311 ? 83.125  87.286  61.301  1.00 54.15  ? 311 LYS   A NZ  1 
ATOM   2210 N N   . THR   A 1 312 ? 80.378  84.173  64.307  1.00 56.46  ? 312 THR   A N   1 
ATOM   2211 C CA  . THR   A 1 312 ? 79.126  83.877  63.618  1.00 56.46  ? 312 THR   A CA  1 
ATOM   2212 C C   . THR   A 1 312 ? 78.263  82.886  64.391  1.00 56.46  ? 312 THR   A C   1 
ATOM   2213 O O   . THR   A 1 312 ? 77.037  82.883  64.229  1.00 56.46  ? 312 THR   A O   1 
ATOM   2214 C CB  . THR   A 1 312 ? 79.417  83.339  62.213  1.00 56.46  ? 312 THR   A CB  1 
ATOM   2215 O OG1 . THR   A 1 312 ? 80.458  84.120  61.614  1.00 56.46  ? 312 THR   A OG1 1 
ATOM   2216 C CG2 . THR   A 1 312 ? 78.182  83.419  61.326  1.00 56.46  ? 312 THR   A CG2 1 
ATOM   2217 N N   . THR   A 1 313 ? 78.875  82.072  65.249  1.00 58.54  ? 313 THR   A N   1 
ATOM   2218 C CA  . THR   A 1 313 ? 78.170  81.116  66.091  1.00 58.54  ? 313 THR   A CA  1 
ATOM   2219 C C   . THR   A 1 313 ? 77.587  81.791  67.332  1.00 58.54  ? 313 THR   A C   1 
ATOM   2220 O O   . THR   A 1 313 ? 76.839  81.158  68.087  1.00 58.54  ? 313 THR   A O   1 
ATOM   2221 C CB  . THR   A 1 313 ? 79.149  79.982  66.453  1.00 58.54  ? 313 THR   A CB  1 
ATOM   2222 O OG1 . THR   A 1 313 ? 79.739  79.483  65.248  1.00 58.54  ? 313 THR   A OG1 1 
ATOM   2223 C CG2 . THR   A 1 313 ? 78.458  78.793  67.118  1.00 58.54  ? 313 THR   A CG2 1 
ATOM   2224 N N   . GLU   A 1 314 ? 77.853  83.091  67.505  1.00 59.37  ? 314 GLU   A N   1 
ATOM   2225 C CA  . GLU   A 1 314 ? 77.559  83.828  68.736  1.00 59.37  ? 314 GLU   A CA  1 
ATOM   2226 C C   . GLU   A 1 314 ? 78.180  83.141  69.948  1.00 59.37  ? 314 GLU   A C   1 
ATOM   2227 O O   . GLU   A 1 314 ? 77.559  83.016  71.005  1.00 59.37  ? 314 GLU   A O   1 
ATOM   2228 C CB  . GLU   A 1 314 ? 76.056  84.067  68.944  1.00 59.37  ? 314 GLU   A CB  1 
ATOM   2229 C CG  . GLU   A 1 314 ? 75.385  85.019  67.940  1.00 59.37  ? 314 GLU   A CG  1 
ATOM   2230 C CD  . GLU   A 1 314 ? 74.969  84.378  66.626  1.00 59.37  ? 314 GLU   A CD  1 
ATOM   2231 O OE1 . GLU   A 1 314 ? 75.123  83.153  66.462  1.00 59.37  ? 314 GLU   A OE1 1 
ATOM   2232 O OE2 . GLU   A 1 314 ? 74.477  85.114  65.744  1.00 59.37  ? 314 GLU   A OE2 1 
ATOM   2233 N N   . GLU   A 1 315 ? 79.421  82.693  69.787  1.00 56.05  ? 315 GLU   A N   1 
ATOM   2234 C CA  . GLU   A 1 315 ? 80.227  82.124  70.858  1.00 56.05  ? 315 GLU   A CA  1 
ATOM   2235 C C   . GLU   A 1 315 ? 81.564  82.847  70.962  1.00 56.05  ? 315 GLU   A C   1 
ATOM   2236 O O   . GLU   A 1 315 ? 82.602  82.237  71.223  1.00 56.05  ? 315 GLU   A O   1 
ATOM   2237 C CB  . GLU   A 1 315 ? 80.437  80.627  70.649  1.00 56.05  ? 315 GLU   A CB  1 
ATOM   2238 C CG  . GLU   A 1 315 ? 79.196  79.790  70.892  1.00 56.05  ? 315 GLU   A CG  1 
ATOM   2239 C CD  . GLU   A 1 315 ? 79.517  78.332  71.142  1.00 56.05  ? 315 GLU   A CD  1 
ATOM   2240 O OE1 . GLU   A 1 315 ? 80.704  77.959  71.042  1.00 56.05  ? 315 GLU   A OE1 1 
ATOM   2241 O OE2 . GLU   A 1 315 ? 78.583  77.559  71.443  1.00 56.05  ? 315 GLU   A OE2 1 
ATOM   2242 N N   . ALA   A 1 316 ? 81.553  84.163  70.734  1.00 47.66  ? 316 ALA   A N   1 
ATOM   2243 C CA  . ALA   A 1 316 ? 82.785  84.941  70.819  1.00 47.66  ? 316 ALA   A CA  1 
ATOM   2244 C C   . ALA   A 1 316 ? 83.297  85.014  72.251  1.00 47.66  ? 316 ALA   A C   1 
ATOM   2245 O O   . ALA   A 1 316 ? 84.509  84.935  72.488  1.00 47.66  ? 316 ALA   A O   1 
ATOM   2246 C CB  . ALA   A 1 316 ? 82.562  86.342  70.254  1.00 47.66  ? 316 ALA   A CB  1 
ATOM   2247 N N   . ASP   A 1 317 ? 82.389  85.119  73.224  1.00 46.01  ? 317 ASP   A N   1 
ATOM   2248 C CA  . ASP   A 1 317 ? 82.770  85.196  74.629  1.00 46.01  ? 317 ASP   A CA  1 
ATOM   2249 C C   . ASP   A 1 317 ? 83.435  83.922  75.131  1.00 46.01  ? 317 ASP   A C   1 
ATOM   2250 O O   . ASP   A 1 317 ? 84.015  83.933  76.222  1.00 46.01  ? 317 ASP   A O   1 
ATOM   2251 C CB  . ASP   A 1 317 ? 81.544  85.519  75.484  1.00 46.01  ? 317 ASP   A CB  1 
ATOM   2252 C CG  . ASP   A 1 317 ? 80.557  84.371  75.548  1.00 46.01  ? 317 ASP   A CG  1 
ATOM   2253 O OD1 . ASP   A 1 317 ? 80.035  83.975  74.486  1.00 46.01  ? 317 ASP   A OD1 1 
ATOM   2254 O OD2 . ASP   A 1 317 ? 80.296  83.869  76.662  1.00 46.01  ? 317 ASP   A OD2 1 
ATOM   2255 N N   . MET   A 1 318 ? 83.362  82.834  74.368  1.00 46.99  ? 318 MET   A N   1 
ATOM   2256 C CA  . MET   A 1 318 ? 84.046  81.589  74.675  1.00 46.99  ? 318 MET   A CA  1 
ATOM   2257 C C   . MET   A 1 318 ? 85.358  81.448  73.912  1.00 46.99  ? 318 MET   A C   1 
ATOM   2258 O O   . MET   A 1 318 ? 85.826  80.323  73.711  1.00 46.99  ? 318 MET   A O   1 
ATOM   2259 C CB  . MET   A 1 318 ? 83.133  80.405  74.353  1.00 46.99  ? 318 MET   A CB  1 
ATOM   2260 C CG  . MET   A 1 318 ? 81.805  80.422  75.080  1.00 46.99  ? 318 MET   A CG  1 
ATOM   2261 S SD  . MET   A 1 318 ? 80.671  79.156  74.487  1.00 46.99  ? 318 MET   A SD  1 
ATOM   2262 C CE  . MET   A 1 318 ? 81.744  77.724  74.476  1.00 46.99  ? 318 MET   A CE  1 
ATOM   2263 N N   . ILE   A 1 319 ? 85.955  82.561  73.473  1.00 38.58  ? 319 ILE   A N   1 
ATOM   2264 C CA  . ILE   A 1 319 ? 87.111  82.474  72.581  1.00 38.58  ? 319 ILE   A CA  1 
ATOM   2265 C C   . ILE   A 1 319 ? 88.335  81.914  73.306  1.00 38.58  ? 319 ILE   A C   1 
ATOM   2266 O O   . ILE   A 1 319 ? 89.121  81.161  72.720  1.00 38.58  ? 319 ILE   A O   1 
ATOM   2267 C CB  . ILE   A 1 319 ? 87.397  83.842  71.927  1.00 38.58  ? 319 ILE   A CB  1 
ATOM   2268 C CG1 . ILE   A 1 319 ? 88.516  83.719  70.891  1.00 38.58  ? 319 ILE   A CG1 1 
ATOM   2269 C CG2 . ILE   A 1 319 ? 87.724  84.913  72.961  1.00 38.58  ? 319 ILE   A CG2 1 
ATOM   2270 C CD1 . ILE   A 1 319 ? 88.233  82.711  69.805  1.00 38.58  ? 319 ILE   A CD1 1 
ATOM   2271 N N   . LEU   A 1 320 ? 88.524  82.269  74.586  1.00 39.45  ? 320 LEU   A N   1 
ATOM   2272 C CA  . LEU   A 1 320 ? 89.691  81.768  75.312  1.00 39.45  ? 320 LEU   A CA  1 
ATOM   2273 C C   . LEU   A 1 320 ? 89.653  80.256  75.523  1.00 39.45  ? 320 LEU   A C   1 
ATOM   2274 O O   . LEU   A 1 320 ? 90.679  79.602  75.269  1.00 39.45  ? 320 LEU   A O   1 
ATOM   2275 C CB  . LEU   A 1 320 ? 89.868  82.541  76.625  1.00 39.45  ? 320 LEU   A CB  1 
ATOM   2276 C CG  . LEU   A 1 320 ? 91.217  82.437  77.349  1.00 39.45  ? 320 LEU   A CG  1 
ATOM   2277 C CD1 . LEU   A 1 320 ? 91.519  83.734  78.061  1.00 39.45  ? 320 LEU   A CD1 1 
ATOM   2278 C CD2 . LEU   A 1 320 ? 91.243  81.290  78.348  1.00 39.45  ? 320 LEU   A CD2 1 
ATOM   2279 N N   . PRO   A 1 321 ? 88.557  79.636  75.993  1.00 39.74  ? 321 PRO   A N   1 
ATOM   2280 C CA  . PRO   A 1 321 ? 88.555  78.166  76.065  1.00 39.74  ? 321 PRO   A CA  1 
ATOM   2281 C C   . PRO   A 1 321 ? 88.682  77.481  74.716  1.00 39.74  ? 321 PRO   A C   1 
ATOM   2282 O O   . PRO   A 1 321 ? 89.235  76.378  74.650  1.00 39.74  ? 321 PRO   A O   1 
ATOM   2283 C CB  . PRO   A 1 321 ? 87.210  77.854  76.731  1.00 39.74  ? 321 PRO   A CB  1 
ATOM   2284 C CG  . PRO   A 1 321 ? 86.916  79.052  77.524  1.00 39.74  ? 321 PRO   A CG  1 
ATOM   2285 C CD  . PRO   A 1 321 ? 87.346  80.175  76.645  1.00 39.74  ? 321 PRO   A CD  1 
ATOM   2286 N N   . ILE   A 1 322 ? 88.181  78.092  73.641  1.00 42.67  ? 322 ILE   A N   1 
ATOM   2287 C CA  . ILE   A 1 322 ? 88.258  77.464  72.324  1.00 42.67  ? 322 ILE   A CA  1 
ATOM   2288 C C   . ILE   A 1 322 ? 89.701  77.420  71.832  1.00 42.67  ? 322 ILE   A C   1 
ATOM   2289 O O   . ILE   A 1 322 ? 90.187  76.376  71.378  1.00 42.67  ? 322 ILE   A O   1 
ATOM   2290 C CB  . ILE   A 1 322 ? 87.339  78.196  71.329  1.00 42.67  ? 322 ILE   A CB  1 
ATOM   2291 C CG1 . ILE   A 1 322 ? 85.875  77.871  71.619  1.00 42.67  ? 322 ILE   A CG1 1 
ATOM   2292 C CG2 . ILE   A 1 322 ? 87.674  77.813  69.904  1.00 42.67  ? 322 ILE   A CG2 1 
ATOM   2293 C CD1 . ILE   A 1 322 ? 84.901  78.810  70.949  1.00 42.67  ? 322 ILE   A CD1 1 
ATOM   2294 N N   . VAL   A 1 323 ? 90.413  78.546  71.944  1.00 42.63  ? 323 VAL   A N   1 
ATOM   2295 C CA  . VAL   A 1 323 ? 91.792  78.631  71.464  1.00 42.63  ? 323 VAL   A CA  1 
ATOM   2296 C C   . VAL   A 1 323 ? 92.686  77.657  72.221  1.00 42.63  ? 323 VAL   A C   1 
ATOM   2297 O O   . VAL   A 1 323 ? 93.519  76.963  71.625  1.00 42.63  ? 323 VAL   A O   1 
ATOM   2298 C CB  . VAL   A 1 323 ? 92.298  80.082  71.576  1.00 42.63  ? 323 VAL   A CB  1 
ATOM   2299 C CG1 . VAL   A 1 323 ? 93.814  80.145  71.483  1.00 42.63  ? 323 VAL   A CG1 1 
ATOM   2300 C CG2 . VAL   A 1 323 ? 91.665  80.944  70.498  1.00 42.63  ? 323 VAL   A CG2 1 
ATOM   2301 N N   . LEU   A 1 324 ? 92.513  77.574  73.542  1.00 44.78  ? 324 LEU   A N   1 
ATOM   2302 C CA  . LEU   A 1 324 ? 93.273  76.612  74.333  1.00 44.78  ? 324 LEU   A CA  1 
ATOM   2303 C C   . LEU   A 1 324 ? 92.908  75.173  73.992  1.00 44.78  ? 324 LEU   A C   1 
ATOM   2304 O O   . LEU   A 1 324 ? 93.708  74.262  74.233  1.00 44.78  ? 324 LEU   A O   1 
ATOM   2305 C CB  . LEU   A 1 324 ? 93.060  76.869  75.825  1.00 44.78  ? 324 LEU   A CB  1 
ATOM   2306 C CG  . LEU   A 1 324 ? 94.059  77.796  76.519  1.00 44.78  ? 324 LEU   A CG  1 
ATOM   2307 C CD1 . LEU   A 1 324 ? 93.836  79.239  76.127  1.00 44.78  ? 324 LEU   A CD1 1 
ATOM   2308 C CD2 . LEU   A 1 324 ? 93.973  77.637  78.024  1.00 44.78  ? 324 LEU   A CD2 1 
ATOM   2309 N N   . GLN   A 1 325 ? 91.718  74.941  73.440  1.00 47.64  ? 325 GLN   A N   1 
ATOM   2310 C CA  . GLN   A 1 325 ? 91.288  73.578  73.157  1.00 47.64  ? 325 GLN   A CA  1 
ATOM   2311 C C   . GLN   A 1 325 ? 91.615  73.148  71.731  1.00 47.64  ? 325 GLN   A C   1 
ATOM   2312 O O   . GLN   A 1 325 ? 92.141  72.052  71.517  1.00 47.64  ? 325 GLN   A O   1 
ATOM   2313 C CB  . GLN   A 1 325 ? 89.787  73.440  73.414  1.00 47.64  ? 325 GLN   A CB  1 
ATOM   2314 C CG  . GLN   A 1 325 ? 89.190  72.116  72.969  1.00 47.64  ? 325 GLN   A CG  1 
ATOM   2315 C CD  . GLN   A 1 325 ? 89.554  70.973  73.891  1.00 47.64  ? 325 GLN   A CD  1 
ATOM   2316 O OE1 . GLN   A 1 325 ? 89.402  71.069  75.108  1.00 47.64  ? 325 GLN   A OE1 1 
ATOM   2317 N NE2 . GLN   A 1 325 ? 90.037  69.879  73.315  1.00 47.64  ? 325 GLN   A NE2 1 
ATOM   2318 N N   . TYR   A 1 326 ? 91.313  73.995  70.749  1.00 49.06  ? 326 TYR   A N   1 
ATOM   2319 C CA  . TYR   A 1 326 ? 91.376  73.601  69.348  1.00 49.06  ? 326 TYR   A CA  1 
ATOM   2320 C C   . TYR   A 1 326 ? 92.675  73.991  68.656  1.00 49.06  ? 326 TYR   A C   1 
ATOM   2321 O O   . TYR   A 1 326 ? 92.902  73.559  67.521  1.00 49.06  ? 326 TYR   A O   1 
ATOM   2322 C CB  . TYR   A 1 326 ? 90.191  74.202  68.583  1.00 49.06  ? 326 TYR   A CB  1 
ATOM   2323 C CG  . TYR   A 1 326 ? 88.852  73.634  69.000  1.00 49.06  ? 326 TYR   A CG  1 
ATOM   2324 C CD1 . TYR   A 1 326 ? 88.144  74.183  70.061  1.00 49.06  ? 326 TYR   A CD1 1 
ATOM   2325 C CD2 . TYR   A 1 326 ? 88.301  72.544  68.339  1.00 49.06  ? 326 TYR   A CD2 1 
ATOM   2326 C CE1 . TYR   A 1 326 ? 86.924  73.667  70.450  1.00 49.06  ? 326 TYR   A CE1 1 
ATOM   2327 C CE2 . TYR   A 1 326 ? 87.081  72.021  68.720  1.00 49.06  ? 326 TYR   A CE2 1 
ATOM   2328 C CZ  . TYR   A 1 326 ? 86.397  72.587  69.776  1.00 49.06  ? 326 TYR   A CZ  1 
ATOM   2329 O OH  . TYR   A 1 326 ? 85.182  72.071  70.161  1.00 49.06  ? 326 TYR   A OH  1 
ATOM   2330 N N   . LEU   A 1 327 ? 93.529  74.787  69.296  1.00 51.31  ? 327 LEU   A N   1 
ATOM   2331 C CA  . LEU   A 1 327 ? 94.782  75.228  68.695  1.00 51.31  ? 327 LEU   A CA  1 
ATOM   2332 C C   . LEU   A 1 327 ? 96.009  74.682  69.413  1.00 51.31  ? 327 LEU   A C   1 
ATOM   2333 O O   . LEU   A 1 327 ? 97.133  75.075  69.084  1.00 51.31  ? 327 LEU   A O   1 
ATOM   2334 C CB  . LEU   A 1 327 ? 94.839  76.756  68.653  1.00 51.31  ? 327 LEU   A CB  1 
ATOM   2335 C CG  . LEU   A 1 327 ? 93.754  77.425  67.813  1.00 51.31  ? 327 LEU   A CG  1 
ATOM   2336 C CD1 . LEU   A 1 327 ? 93.759  78.923  68.006  1.00 51.31  ? 327 LEU   A CD1 1 
ATOM   2337 C CD2 . LEU   A 1 327 ? 93.986  77.089  66.364  1.00 51.31  ? 327 LEU   A CD2 1 
ATOM   2338 N N   . CYS   A 1 328 ? 95.826  73.785  70.372  1.00 53.77  ? 328 CYS   A N   1 
ATOM   2339 C CA  . CYS   A 1 328 ? 96.904  73.228  71.169  1.00 53.77  ? 328 CYS   A CA  1 
ATOM   2340 C C   . CYS   A 1 328 ? 96.889  71.708  71.075  1.00 53.77  ? 328 CYS   A C   1 
ATOM   2341 O O   . CYS   A 1 328 ? 95.846  71.107  70.790  1.00 53.77  ? 328 CYS   A O   1 
ATOM   2342 C CB  . CYS   A 1 328 ? 96.769  73.663  72.636  1.00 53.77  ? 328 CYS   A CB  1 
ATOM   2343 S SG  . CYS   A 1 328 ? 96.894  75.443  72.901  1.00 53.77  ? 328 CYS   A SG  1 
ATOM   2344 N N   . PRO   A 1 329 ? 98.031  71.053  71.286  1.00 57.60  ? 329 PRO   A N   1 
ATOM   2345 C CA  . PRO   A 1 329 ? 98.049  69.587  71.304  1.00 57.60  ? 329 PRO   A CA  1 
ATOM   2346 C C   . PRO   A 1 329 ? 97.240  69.036  72.468  1.00 57.60  ? 329 PRO   A C   1 
ATOM   2347 O O   . PRO   A 1 329 ? 96.960  69.728  73.448  1.00 57.60  ? 329 PRO   A O   1 
ATOM   2348 C CB  . PRO   A 1 329 ? 99.536  69.246  71.450  1.00 57.60  ? 329 PRO   A CB  1 
ATOM   2349 C CG  . PRO   A 1 329 ? 100.255 70.461  70.984  1.00 57.60  ? 329 PRO   A CG  1 
ATOM   2350 C CD  . PRO   A 1 329 ? 99.390  71.617  71.365  1.00 57.60  ? 329 PRO   A CD  1 
ATOM   2351 N N   . VAL   A 1 330 ? 96.861  67.761  72.336  1.00 59.33  ? 330 VAL   A N   1 
ATOM   2352 C CA  . VAL   A 1 330 ? 95.901  67.157  73.258  1.00 59.33  ? 330 VAL   A CA  1 
ATOM   2353 C C   . VAL   A 1 330 ? 96.456  67.104  74.677  1.00 59.33  ? 330 VAL   A C   1 
ATOM   2354 O O   . VAL   A 1 330 ? 95.721  67.318  75.647  1.00 59.33  ? 330 VAL   A O   1 
ATOM   2355 C CB  . VAL   A 1 330 ? 95.482  65.762  72.755  1.00 59.33  ? 330 VAL   A CB  1 
ATOM   2356 C CG1 . VAL   A 1 330 ? 94.521  65.891  71.587  1.00 59.33  ? 330 VAL   A CG1 1 
ATOM   2357 C CG2 . VAL   A 1 330 ? 96.701  64.950  72.344  1.00 59.33  ? 330 VAL   A CG2 1 
ATOM   2358 N N   . TYR   A 1 331 ? 97.754  66.840  74.827  1.00 61.22  ? 331 TYR   A N   1 
ATOM   2359 C CA  . TYR   A 1 331 ? 98.343  66.813  76.162  1.00 61.22  ? 331 TYR   A CA  1 
ATOM   2360 C C   . TYR   A 1 331 ? 98.515  68.218  76.731  1.00 61.22  ? 331 TYR   A C   1 
ATOM   2361 O O   . TYR   A 1 331 ? 98.255  68.442  77.920  1.00 61.22  ? 331 TYR   A O   1 
ATOM   2362 C CB  . TYR   A 1 331 ? 99.673  66.051  76.139  1.00 61.22  ? 331 TYR   A CB  1 
ATOM   2363 C CG  . TYR   A 1 331 ? 100.733 66.605  75.210  1.00 61.22  ? 331 TYR   A CG  1 
ATOM   2364 C CD1 . TYR   A 1 331 ? 100.728 66.298  73.854  1.00 61.22  ? 331 TYR   A CD1 1 
ATOM   2365 C CD2 . TYR   A 1 331 ? 101.764 67.398  75.696  1.00 61.22  ? 331 TYR   A CD2 1 
ATOM   2366 C CE1 . TYR   A 1 331 ? 101.700 66.791  73.005  1.00 61.22  ? 331 TYR   A CE1 1 
ATOM   2367 C CE2 . TYR   A 1 331 ? 102.745 67.889  74.854  1.00 61.22  ? 331 TYR   A CE2 1 
ATOM   2368 C CZ  . TYR   A 1 331 ? 102.705 67.586  73.511  1.00 61.22  ? 331 TYR   A CZ  1 
ATOM   2369 O OH  . TYR   A 1 331 ? 103.677 68.076  72.670  1.00 61.22  ? 331 TYR   A OH  1 
ATOM   2370 N N   . ILE   A 1 332 ? 98.930  69.178  75.898  1.00 57.59  ? 332 ILE   A N   1 
ATOM   2371 C CA  . ILE   A 1 332 ? 99.013  70.567  76.344  1.00 57.59  ? 332 ILE   A CA  1 
ATOM   2372 C C   . ILE   A 1 332 ? 97.629  71.104  76.680  1.00 57.59  ? 332 ILE   A C   1 
ATOM   2373 O O   . ILE   A 1 332 ? 97.442  71.776  77.703  1.00 57.59  ? 332 ILE   A O   1 
ATOM   2374 C CB  . ILE   A 1 332 ? 99.713  71.436  75.283  1.00 57.59  ? 332 ILE   A CB  1 
ATOM   2375 C CG1 . ILE   A 1 332 ? 101.158 70.987  75.098  1.00 57.59  ? 332 ILE   A CG1 1 
ATOM   2376 C CG2 . ILE   A 1 332 ? 99.670  72.904  75.674  1.00 57.59  ? 332 ILE   A CG2 1 
ATOM   2377 C CD1 . ILE   A 1 332 ? 101.993 71.111  76.351  1.00 57.59  ? 332 ILE   A CD1 1 
ATOM   2378 N N   . SER   A 1 333 ? 96.639  70.821  75.825  1.00 57.74  ? 333 SER   A N   1 
ATOM   2379 C CA  . SER   A 1 333 ? 95.267  71.232  76.109  1.00 57.74  ? 333 SER   A CA  1 
ATOM   2380 C C   . SER   A 1 333 ? 94.787  70.634  77.421  1.00 57.74  ? 333 SER   A C   1 
ATOM   2381 O O   . SER   A 1 333 ? 94.304  71.356  78.299  1.00 57.74  ? 333 SER   A O   1 
ATOM   2382 C CB  . SER   A 1 333 ? 94.338  70.819  74.967  1.00 57.74  ? 333 SER   A CB  1 
ATOM   2383 O OG  . SER   A 1 333 ? 94.802  71.304  73.721  1.00 57.74  ? 333 SER   A OG  1 
ATOM   2384 N N   . PHE   A 1 334 ? 94.981  69.322  77.587  1.00 61.72  ? 334 PHE   A N   1 
ATOM   2385 C CA  . PHE   A 1 334 ? 94.626  68.608  78.810  1.00 61.72  ? 334 PHE   A CA  1 
ATOM   2386 C C   . PHE   A 1 334 ? 95.206  69.309  80.034  1.00 61.72  ? 334 PHE   A C   1 
ATOM   2387 O O   . PHE   A 1 334 ? 94.465  69.864  80.853  1.00 61.72  ? 334 PHE   A O   1 
ATOM   2388 C CB  . PHE   A 1 334 ? 95.120  67.157  78.676  1.00 61.72  ? 334 PHE   A CB  1 
ATOM   2389 C CG  . PHE   A 1 334 ? 95.032  66.325  79.934  1.00 61.72  ? 334 PHE   A CG  1 
ATOM   2390 C CD1 . PHE   A 1 334 ? 96.071  66.295  80.856  1.00 61.72  ? 334 PHE   A CD1 1 
ATOM   2391 C CD2 . PHE   A 1 334 ? 93.931  65.516  80.157  1.00 61.72  ? 334 PHE   A CD2 1 
ATOM   2392 C CE1 . PHE   A 1 334 ? 95.989  65.514  81.993  1.00 61.72  ? 334 PHE   A CE1 1 
ATOM   2393 C CE2 . PHE   A 1 334 ? 93.848  64.727  81.288  1.00 61.72  ? 334 PHE   A CE2 1 
ATOM   2394 C CZ  . PHE   A 1 334 ? 94.877  64.729  82.209  1.00 61.72  ? 334 PHE   A CZ  1 
ATOM   2395 N N   . PHE   A 1 335 ? 96.539  69.392  80.102  1.00 64.05  ? 335 PHE   A N   1 
ATOM   2396 C CA  . PHE   A 1 335 ? 97.215  69.949  81.272  1.00 64.05  ? 335 PHE   A CA  1 
ATOM   2397 C C   . PHE   A 1 335 ? 96.825  71.404  81.511  1.00 64.05  ? 335 PHE   A C   1 
ATOM   2398 O O   . PHE   A 1 335 ? 96.255  71.744  82.557  1.00 64.05  ? 335 PHE   A O   1 
ATOM   2399 C CB  . PHE   A 1 335 ? 98.731  69.828  81.104  1.00 64.05  ? 335 PHE   A CB  1 
ATOM   2400 C CG  . PHE   A 1 335 ? 99.300  68.534  81.609  1.00 64.05  ? 335 PHE   A CG  1 
ATOM   2401 C CD1 . PHE   A 1 335 ? 99.341  67.414  80.794  1.00 64.05  ? 335 PHE   A CD1 1 
ATOM   2402 C CD2 . PHE   A 1 335 ? 99.801  68.439  82.896  1.00 64.05  ? 335 PHE   A CD2 1 
ATOM   2403 C CE1 . PHE   A 1 335 ? 99.866  66.222  81.255  1.00 64.05  ? 335 PHE   A CE1 1 
ATOM   2404 C CE2 . PHE   A 1 335 ? 100.329 67.250  83.364  1.00 64.05  ? 335 PHE   A CE2 1 
ATOM   2405 C CZ  . PHE   A 1 335 ? 100.362 66.139  82.541  1.00 64.05  ? 335 PHE   A CZ  1 
ATOM   2406 N N   . GLY   A 1 336 ? 97.130  72.279  80.549  1.00 57.72  ? 336 GLY   A N   1 
ATOM   2407 C CA  . GLY   A 1 336 ? 96.952  73.705  80.770  1.00 57.72  ? 336 GLY   A CA  1 
ATOM   2408 C C   . GLY   A 1 336 ? 95.503  74.106  80.958  1.00 57.72  ? 336 GLY   A C   1 
ATOM   2409 O O   . GLY   A 1 336 ? 95.172  74.862  81.874  1.00 57.72  ? 336 GLY   A O   1 
ATOM   2410 N N   . LEU   A 1 337 ? 94.613  73.609  80.094  1.00 52.04  ? 337 LEU   A N   1 
ATOM   2411 C CA  . LEU   A 1 337 ? 93.225  74.030  80.174  1.00 52.04  ? 337 LEU   A CA  1 
ATOM   2412 C C   . LEU   A 1 337 ? 92.514  73.398  81.365  1.00 52.04  ? 337 LEU   A C   1 
ATOM   2413 O O   . LEU   A 1 337 ? 91.627  74.030  81.943  1.00 52.04  ? 337 LEU   A O   1 
ATOM   2414 C CB  . LEU   A 1 337 ? 92.524  73.713  78.853  1.00 52.04  ? 337 LEU   A CB  1 
ATOM   2415 C CG  . LEU   A 1 337 ? 91.068  74.124  78.657  1.00 52.04  ? 337 LEU   A CG  1 
ATOM   2416 C CD1 . LEU   A 1 337 ? 90.911  75.626  78.735  1.00 52.04  ? 337 LEU   A CD1 1 
ATOM   2417 C CD2 . LEU   A 1 337 ? 90.597  73.626  77.305  1.00 52.04  ? 337 LEU   A CD2 1 
ATOM   2418 N N   . GLY   A 1 338 ? 92.907  72.190  81.790  1.00 54.90  ? 338 GLY   A N   1 
ATOM   2419 C CA  . GLY   A 1 338 ? 92.374  71.660  83.032  1.00 54.90  ? 338 GLY   A CA  1 
ATOM   2420 C C   . GLY   A 1 338 ? 92.840  72.440  84.246  1.00 54.90  ? 338 GLY   A C   1 
ATOM   2421 O O   . GLY   A 1 338 ? 92.067  72.666  85.182  1.00 54.90  ? 338 GLY   A O   1 
ATOM   2422 N N   . ALA   A 1 339 ? 94.109  72.865  84.249  1.00 54.80  ? 339 ALA   A N   1 
ATOM   2423 C CA  . ALA   A 1 339 ? 94.605  73.697  85.341  1.00 54.80  ? 339 ALA   A CA  1 
ATOM   2424 C C   . ALA   A 1 339 ? 93.870  75.030  85.395  1.00 54.80  ? 339 ALA   A C   1 
ATOM   2425 O O   . ALA   A 1 339 ? 93.492  75.496  86.478  1.00 54.80  ? 339 ALA   A O   1 
ATOM   2426 C CB  . ALA   A 1 339 ? 96.108  73.919  85.190  1.00 54.80  ? 339 ALA   A CB  1 
ATOM   2427 N N   . VAL   A 1 340 ? 93.647  75.648  84.232  1.00 53.00  ? 340 VAL   A N   1 
ATOM   2428 C CA  . VAL   A 1 340 ? 92.895  76.899  84.175  1.00 53.00  ? 340 VAL   A CA  1 
ATOM   2429 C C   . VAL   A 1 340 ? 91.463  76.685  84.651  1.00 53.00  ? 340 VAL   A C   1 
ATOM   2430 O O   . VAL   A 1 340 ? 90.921  77.499  85.408  1.00 53.00  ? 340 VAL   A O   1 
ATOM   2431 C CB  . VAL   A 1 340 ? 92.942  77.489  82.752  1.00 53.00  ? 340 VAL   A CB  1 
ATOM   2432 C CG1 . VAL   A 1 340 ? 91.973  78.651  82.616  1.00 53.00  ? 340 VAL   A CG1 1 
ATOM   2433 C CG2 . VAL   A 1 340 ? 94.348  77.947  82.420  1.00 53.00  ? 340 VAL   A CG2 1 
ATOM   2434 N N   . SER   A 1 341 ? 90.834  75.583  84.229  1.00 52.36  ? 341 SER   A N   1 
ATOM   2435 C CA  . SER   A 1 341 ? 89.462  75.290  84.634  1.00 52.36  ? 341 SER   A CA  1 
ATOM   2436 C C   . SER   A 1 341 ? 89.354  75.128  86.144  1.00 52.36  ? 341 SER   A C   1 
ATOM   2437 O O   . SER   A 1 341 ? 88.452  75.688  86.776  1.00 52.36  ? 341 SER   A O   1 
ATOM   2438 C CB  . SER   A 1 341 ? 88.976  74.023  83.934  1.00 52.36  ? 341 SER   A CB  1 
ATOM   2439 O OG  . SER   A 1 341 ? 89.054  74.142  82.528  1.00 52.36  ? 341 SER   A OG  1 
ATOM   2440 N N   . ALA   A 1 342 ? 90.277  74.369  86.740  1.00 54.61  ? 342 ALA   A N   1 
ATOM   2441 C CA  . ALA   A 1 342 ? 90.243  74.154  88.183  1.00 54.61  ? 342 ALA   A CA  1 
ATOM   2442 C C   . ALA   A 1 342 ? 90.519  75.441  88.949  1.00 54.61  ? 342 ALA   A C   1 
ATOM   2443 O O   . ALA   A 1 342 ? 89.873  75.709  89.969  1.00 54.61  ? 342 ALA   A O   1 
ATOM   2444 C CB  . ALA   A 1 342 ? 91.246  73.076  88.577  1.00 54.61  ? 342 ALA   A CB  1 
ATOM   2445 N N   . ALA   A 1 343 ? 91.473  76.249  88.479  1.00 55.12  ? 343 ALA   A N   1 
ATOM   2446 C CA  . ALA   A 1 343 ? 91.775  77.502  89.162  1.00 55.12  ? 343 ALA   A CA  1 
ATOM   2447 C C   . ALA   A 1 343 ? 90.607  78.478  89.082  1.00 55.12  ? 343 ALA   A C   1 
ATOM   2448 O O   . ALA   A 1 343 ? 90.288  79.155  90.067  1.00 55.12  ? 343 ALA   A O   1 
ATOM   2449 C CB  . ALA   A 1 343 ? 93.039  78.122  88.575  1.00 55.12  ? 343 ALA   A CB  1 
ATOM   2450 N N   . VAL   A 1 344 ? 89.954  78.559  87.920  1.00 53.91  ? 344 VAL   A N   1 
ATOM   2451 C CA  . VAL   A 1 344 ? 88.788  79.422  87.769  1.00 53.91  ? 344 VAL   A CA  1 
ATOM   2452 C C   . VAL   A 1 344 ? 87.639  78.929  88.641  1.00 53.91  ? 344 VAL   A C   1 
ATOM   2453 O O   . VAL   A 1 344 ? 86.945  79.726  89.284  1.00 53.91  ? 344 VAL   A O   1 
ATOM   2454 C CB  . VAL   A 1 344 ? 88.390  79.512  86.284  1.00 53.91  ? 344 VAL   A CB  1 
ATOM   2455 C CG1 . VAL   A 1 344 ? 87.011  80.129  86.121  1.00 53.91  ? 344 VAL   A CG1 1 
ATOM   2456 C CG2 . VAL   A 1 344 ? 89.419  80.318  85.517  1.00 53.91  ? 344 VAL   A CG2 1 
ATOM   2457 N N   . MET   A 1 345 ? 87.431  77.609  88.691  1.00 58.04  ? 345 MET   A N   1 
ATOM   2458 C CA  . MET   A 1 345 ? 86.374  77.043  89.524  1.00 58.04  ? 345 MET   A CA  1 
ATOM   2459 C C   . MET   A 1 345 ? 86.621  77.322  91.001  1.00 58.04  ? 345 MET   A C   1 
ATOM   2460 O O   . MET   A 1 345 ? 85.683  77.623  91.748  1.00 58.04  ? 345 MET   A O   1 
ATOM   2461 C CB  . MET   A 1 345 ? 86.272  75.540  89.272  1.00 58.04  ? 345 MET   A CB  1 
ATOM   2462 C CG  . MET   A 1 345 ? 85.120  74.855  89.978  1.00 58.04  ? 345 MET   A CG  1 
ATOM   2463 S SD  . MET   A 1 345 ? 84.881  73.174  89.378  1.00 58.04  ? 345 MET   A SD  1 
ATOM   2464 C CE  . MET   A 1 345 ? 83.095  73.070  89.359  1.00 58.04  ? 345 MET   A CE  1 
ATOM   2465 N N   . SER   A 1 346 ? 87.876  77.222  91.440  1.00 62.20  ? 346 SER   A N   1 
ATOM   2466 C CA  . SER   A 1 346 ? 88.198  77.505  92.834  1.00 62.20  ? 346 SER   A CA  1 
ATOM   2467 C C   . SER   A 1 346 ? 88.066  78.991  93.147  1.00 62.20  ? 346 SER   A C   1 
ATOM   2468 O O   . SER   A 1 346 ? 87.656  79.362  94.253  1.00 62.20  ? 346 SER   A O   1 
ATOM   2469 C CB  . SER   A 1 346 ? 89.607  77.011  93.154  1.00 62.20  ? 346 SER   A CB  1 
ATOM   2470 O OG  . SER   A 1 346 ? 89.686  75.600  93.076  1.00 62.20  ? 346 SER   A OG  1 
ATOM   2471 N N   . SER   A 1 347 ? 88.406  79.856  92.193  1.00 65.42  ? 347 SER   A N   1 
ATOM   2472 C CA  . SER   A 1 347 ? 88.349  81.297  92.395  1.00 65.42  ? 347 SER   A CA  1 
ATOM   2473 C C   . SER   A 1 347 ? 87.022  81.909  91.959  1.00 65.42  ? 347 SER   A C   1 
ATOM   2474 O O   . SER   A 1 347 ? 86.901  83.138  91.933  1.00 65.42  ? 347 SER   A O   1 
ATOM   2475 C CB  . SER   A 1 347 ? 89.500  81.980  91.653  1.00 65.42  ? 347 SER   A CB  1 
ATOM   2476 O OG  . SER   A 1 347 ? 89.337  81.875  90.250  1.00 65.42  ? 347 SER   A OG  1 
ATOM   2477 N N   . ALA   A 1 348 ? 86.033  81.086  91.608  1.00 67.33  ? 348 ALA   A N   1 
ATOM   2478 C CA  . ALA   A 1 348 ? 84.768  81.618  91.112  1.00 67.33  ? 348 ALA   A CA  1 
ATOM   2479 C C   . ALA   A 1 348 ? 83.918  82.222  92.222  1.00 67.33  ? 348 ALA   A C   1 
ATOM   2480 O O   . ALA   A 1 348 ? 83.118  83.128  91.963  1.00 67.33  ? 348 ALA   A O   1 
ATOM   2481 C CB  . ALA   A 1 348 ? 83.983  80.522  90.392  1.00 67.33  ? 348 ALA   A CB  1 
ATOM   2482 N N   . ASP   A 1 349 ? 84.068  81.742  93.452  1.00 78.25  ? 349 ASP   A N   1 
ATOM   2483 C CA  . ASP   A 1 349 ? 83.135  82.059  94.523  1.00 78.25  ? 349 ASP   A CA  1 
ATOM   2484 C C   . ASP   A 1 349 ? 83.557  83.239  95.394  1.00 78.25  ? 349 ASP   A C   1 
ATOM   2485 O O   . ASP   A 1 349 ? 82.838  83.563  96.342  1.00 78.25  ? 349 ASP   A O   1 
ATOM   2486 C CB  . ASP   A 1 349 ? 82.919  80.821  95.402  1.00 78.25  ? 349 ASP   A CB  1 
ATOM   2487 C CG  . ASP   A 1 349 ? 84.220  80.239  95.925  1.00 78.25  ? 349 ASP   A CG  1 
ATOM   2488 O OD1 . ASP   A 1 349 ? 85.301  80.735  95.543  1.00 78.25  ? 349 ASP   A OD1 1 
ATOM   2489 O OD2 . ASP   A 1 349 ? 84.162  79.275  96.717  1.00 78.25  ? 349 ASP   A OD2 1 
ATOM   2490 N N   . SER   A 1 350 ? 84.687  83.890  95.100  1.00 79.22  ? 350 SER   A N   1 
ATOM   2491 C CA  . SER   A 1 350 ? 85.178  84.958  95.971  1.00 79.22  ? 350 SER   A CA  1 
ATOM   2492 C C   . SER   A 1 350 ? 84.209  86.136  96.024  1.00 79.22  ? 350 SER   A C   1 
ATOM   2493 O O   . SER   A 1 350 ? 83.962  86.703  97.099  1.00 79.22  ? 350 SER   A O   1 
ATOM   2494 C CB  . SER   A 1 350 ? 86.556  85.422  95.501  1.00 79.22  ? 350 SER   A CB  1 
ATOM   2495 O OG  . SER   A 1 350 ? 87.491  84.358  95.540  1.00 79.22  ? 350 SER   A OG  1 
ATOM   2496 N N   . SER   A 1 351 ? 83.646  86.513  94.872  1.00 73.42  ? 351 SER   A N   1 
ATOM   2497 C CA  . SER   A 1 351 ? 82.656  87.585  94.844  1.00 73.42  ? 351 SER   A CA  1 
ATOM   2498 C C   . SER   A 1 351 ? 81.406  87.211  95.626  1.00 73.42  ? 351 SER   A C   1 
ATOM   2499 O O   . SER   A 1 351 ? 80.778  88.080  96.243  1.00 73.42  ? 351 SER   A O   1 
ATOM   2500 C CB  . SER   A 1 351 ? 82.297  87.931  93.399  1.00 73.42  ? 351 SER   A CB  1 
ATOM   2501 O OG  . SER   A 1 351 ? 81.466  89.076  93.341  1.00 73.42  ? 351 SER   A OG  1 
ATOM   2502 N N   . ILE   A 1 352 ? 81.038  85.925  95.620  1.00 77.04  ? 352 ILE   A N   1 
ATOM   2503 C CA  . ILE   A 1 352 ? 79.888  85.465  96.395  1.00 77.04  ? 352 ILE   A CA  1 
ATOM   2504 C C   . ILE   A 1 352 ? 80.120  85.706  97.880  1.00 77.04  ? 352 ILE   A C   1 
ATOM   2505 O O   . ILE   A 1 352 ? 79.262  86.262  98.576  1.00 77.04  ? 352 ILE   A O   1 
ATOM   2506 C CB  . ILE   A 1 352 ? 79.608  83.979  96.110  1.00 77.04  ? 352 ILE   A CB  1 
ATOM   2507 C CG1 . ILE   A 1 352 ? 79.268  83.760  94.638  1.00 77.04  ? 352 ILE   A CG1 1 
ATOM   2508 C CG2 . ILE   A 1 352 ? 78.480  83.472  96.993  1.00 77.04  ? 352 ILE   A CG2 1 
ATOM   2509 C CD1 . ILE   A 1 352 ? 79.248  82.304  94.245  1.00 77.04  ? 352 ILE   A CD1 1 
ATOM   2510 N N   . LEU   A 1 353 ? 81.292  85.300  98.383  1.00 81.63  ? 353 LEU   A N   1 
ATOM   2511 C CA  . LEU   A 1 353 ? 81.609  85.513  99.793  1.00 81.63  ? 353 LEU   A CA  1 
ATOM   2512 C C   . LEU   A 1 353 ? 81.659  86.994  100.135 1.00 81.63  ? 353 LEU   A C   1 
ATOM   2513 O O   . LEU   A 1 353 ? 81.143  87.407  101.178 1.00 81.63  ? 353 LEU   A O   1 
ATOM   2514 C CB  . LEU   A 1 353 ? 82.934  84.846  100.169 1.00 81.63  ? 353 LEU   A CB  1 
ATOM   2515 C CG  . LEU   A 1 353 ? 82.990  83.355  100.520 1.00 81.63  ? 353 LEU   A CG  1 
ATOM   2516 C CD1 . LEU   A 1 353 ? 82.866  82.466  99.305  1.00 81.63  ? 353 LEU   A CD1 1 
ATOM   2517 C CD2 . LEU   A 1 353 ? 84.268  83.041  101.285 1.00 81.63  ? 353 LEU   A CD2 1 
ATOM   2518 N N   . SER   A 1 354 ? 82.265  87.811  99.268  1.00 82.48  ? 354 SER   A N   1 
ATOM   2519 C CA  . SER   A 1 354 ? 82.372  89.239  99.563  1.00 82.48  ? 354 SER   A CA  1 
ATOM   2520 C C   . SER   A 1 354 ? 80.996  89.897  99.626  1.00 82.48  ? 354 SER   A C   1 
ATOM   2521 O O   . SER   A 1 354 ? 80.675  90.601  100.593 1.00 82.48  ? 354 SER   A O   1 
ATOM   2522 C CB  . SER   A 1 354 ? 83.251  89.928  98.520  1.00 82.48  ? 354 SER   A CB  1 
ATOM   2523 O OG  . SER   A 1 354 ? 82.681  89.833  97.228  1.00 82.48  ? 354 SER   A OG  1 
ATOM   2524 N N   . ALA   A 1 355 ? 80.157  89.652  98.613  1.00 84.37  ? 355 ALA   A N   1 
ATOM   2525 C CA  . ALA   A 1 355 ? 78.829  90.258  98.579  1.00 84.37  ? 355 ALA   A CA  1 
ATOM   2526 C C   . ALA   A 1 355 ? 77.954  89.754  99.720  1.00 84.37  ? 355 ALA   A C   1 
ATOM   2527 O O   . ALA   A 1 355 ? 77.216  90.533  100.333 1.00 84.37  ? 355 ALA   A O   1 
ATOM   2528 C CB  . ALA   A 1 355 ? 78.160  89.983  97.233  1.00 84.37  ? 355 ALA   A CB  1 
ATOM   2529 N N   . SER   A 1 356 ? 78.028  88.457  100.029 1.00 87.45  ? 356 SER   A N   1 
ATOM   2530 C CA  . SER   A 1 356 ? 77.187  87.903  101.083 1.00 87.45  ? 356 SER   A CA  1 
ATOM   2531 C C   . SER   A 1 356 ? 77.629  88.378  102.462 1.00 87.45  ? 356 SER   A C   1 
ATOM   2532 O O   . SER   A 1 356 ? 76.788  88.647  103.327 1.00 87.45  ? 356 SER   A O   1 
ATOM   2533 C CB  . SER   A 1 356 ? 77.201  86.381  101.000 1.00 87.45  ? 356 SER   A CB  1 
ATOM   2534 O OG  . SER   A 1 356 ? 76.798  85.941  99.715  1.00 87.45  ? 356 SER   A OG  1 
ATOM   2535 N N   . SER   A 1 357 ? 78.942  88.488  102.689 1.00 90.91  ? 357 SER   A N   1 
ATOM   2536 C CA  . SER   A 1 357 ? 79.431  89.039  103.947 1.00 90.91  ? 357 SER   A CA  1 
ATOM   2537 C C   . SER   A 1 357 ? 79.041  90.503  104.092 1.00 90.91  ? 357 SER   A C   1 
ATOM   2538 O O   . SER   A 1 357 ? 78.687  90.948  105.190 1.00 90.91  ? 357 SER   A O   1 
ATOM   2539 C CB  . SER   A 1 357 ? 80.948  88.874  104.037 1.00 90.91  ? 357 SER   A CB  1 
ATOM   2540 O OG  . SER   A 1 357 ? 81.445  89.380  105.264 1.00 90.91  ? 357 SER   A OG  1 
ATOM   2541 N N   . MET   A 1 358 ? 79.095  91.264  102.994 1.00 92.65  ? 358 MET   A N   1 
ATOM   2542 C CA  . MET   A 1 358 ? 78.649  92.654  103.031 1.00 92.65  ? 358 MET   A CA  1 
ATOM   2543 C C   . MET   A 1 358 ? 77.159  92.746  103.345 1.00 92.65  ? 358 MET   A C   1 
ATOM   2544 O O   . MET   A 1 358 ? 76.733  93.602  104.131 1.00 92.65  ? 358 MET   A O   1 
ATOM   2545 C CB  . MET   A 1 358 ? 78.967  93.324  101.695 1.00 92.65  ? 358 MET   A CB  1 
ATOM   2546 C CG  . MET   A 1 358 ? 78.879  94.835  101.694 1.00 92.65  ? 358 MET   A CG  1 
ATOM   2547 S SD  . MET   A 1 358 ? 79.597  95.516  100.189 1.00 92.65  ? 358 MET   A SD  1 
ATOM   2548 C CE  . MET   A 1 358 ? 78.781  94.523  98.942  1.00 92.65  ? 358 MET   A CE  1 
ATOM   2549 N N   . PHE   A 1 359 ? 76.359  91.856  102.750 1.00 96.38  ? 359 PHE   A N   1 
ATOM   2550 C CA  . PHE   A 1 359 ? 74.924  91.817  103.017 1.00 96.38  ? 359 PHE   A CA  1 
ATOM   2551 C C   . PHE   A 1 359 ? 74.637  91.478  104.475 1.00 96.38  ? 359 PHE   A C   1 
ATOM   2552 O O   . PHE   A 1 359 ? 73.749  92.072  105.097 1.00 96.38  ? 359 PHE   A O   1 
ATOM   2553 C CB  . PHE   A 1 359 ? 74.257  90.796  102.095 1.00 96.38  ? 359 PHE   A CB  1 
ATOM   2554 C CG  . PHE   A 1 359 ? 72.767  90.704  102.260 1.00 96.38  ? 359 PHE   A CG  1 
ATOM   2555 C CD1 . PHE   A 1 359 ? 71.937  91.679  101.741 1.00 96.38  ? 359 PHE   A CD1 1 
ATOM   2556 C CD2 . PHE   A 1 359 ? 72.198  89.641  102.943 1.00 96.38  ? 359 PHE   A CD2 1 
ATOM   2557 C CE1 . PHE   A 1 359 ? 70.566  91.597  101.895 1.00 96.38  ? 359 PHE   A CE1 1 
ATOM   2558 C CE2 . PHE   A 1 359 ? 70.828  89.553  103.101 1.00 96.38  ? 359 PHE   A CE2 1 
ATOM   2559 C CZ  . PHE   A 1 359 ? 70.012  90.532  102.576 1.00 96.38  ? 359 PHE   A CZ  1 
ATOM   2560 N N   . ALA   A 1 360 ? 75.370  90.512  105.031 1.00 99.66  ? 360 ALA   A N   1 
ATOM   2561 C CA  . ALA   A 1 360 ? 75.142  90.111  106.415 1.00 99.66  ? 360 ALA   A CA  1 
ATOM   2562 C C   . ALA   A 1 360 ? 75.582  91.195  107.392 1.00 99.66  ? 360 ALA   A C   1 
ATOM   2563 O O   . ALA   A 1 360 ? 74.891  91.461  108.382 1.00 99.66  ? 360 ALA   A O   1 
ATOM   2564 C CB  . ALA   A 1 360 ? 75.868  88.799  106.706 1.00 99.66  ? 360 ALA   A CB  1 
ATOM   2565 N N   . ARG   A 1 361 ? 76.726  91.831  107.134 1.00 102.74 ? 361 ARG   A N   1 
ATOM   2566 C CA  . ARG   A 1 361 ? 77.269  92.796  108.084 1.00 102.74 ? 361 ARG   A CA  1 
ATOM   2567 C C   . ARG   A 1 361 ? 76.519  94.122  108.024 1.00 102.74 ? 361 ARG   A C   1 
ATOM   2568 O O   . ARG   A 1 361 ? 76.094  94.651  109.058 1.00 102.74 ? 361 ARG   A O   1 
ATOM   2569 C CB  . ARG   A 1 361 ? 78.761  93.002  107.812 1.00 102.74 ? 361 ARG   A CB  1 
ATOM   2570 C CG  . ARG   A 1 361 ? 79.349  94.313  108.333 1.00 102.74 ? 361 ARG   A CG  1 
ATOM   2571 C CD  . ARG   A 1 361 ? 79.385  94.368  109.856 1.00 102.74 ? 361 ARG   A CD  1 
ATOM   2572 N NE  . ARG   A 1 361 ? 79.652  95.717  110.342 1.00 102.74 ? 361 ARG   A NE  1 
ATOM   2573 C CZ  . ARG   A 1 361 ? 80.820  96.126  110.817 1.00 102.74 ? 361 ARG   A CZ  1 
ATOM   2574 N NH1 . ARG   A 1 361 ? 81.863  95.313  110.882 1.00 102.74 ? 361 ARG   A NH1 1 
ATOM   2575 N NH2 . ARG   A 1 361 ? 80.947  97.382  111.235 1.00 102.74 ? 361 ARG   A NH2 1 
ATOM   2576 N N   . ASN   A 1 362 ? 76.341  94.677  106.824 1.00 102.95 ? 362 ASN   A N   1 
ATOM   2577 C CA  . ASN   A 1 362 ? 75.910  96.067  106.719 1.00 102.95 ? 362 ASN   A CA  1 
ATOM   2578 C C   . ASN   A 1 362 ? 74.401  96.220  106.881 1.00 102.95 ? 362 ASN   A C   1 
ATOM   2579 O O   . ASN   A 1 362 ? 73.930  96.881  107.812 1.00 102.95 ? 362 ASN   A O   1 
ATOM   2580 C CB  . ASN   A 1 362 ? 76.370  96.654  105.382 1.00 102.95 ? 362 ASN   A CB  1 
ATOM   2581 C CG  . ASN   A 1 362 ? 77.852  96.970  105.366 1.00 102.95 ? 362 ASN   A CG  1 
ATOM   2582 O OD1 . ASN   A 1 362 ? 78.618  96.376  104.608 1.00 102.95 ? 362 ASN   A OD1 1 
ATOM   2583 N ND2 . ASN   A 1 362 ? 78.264  97.912  106.206 1.00 102.95 ? 362 ASN   A ND2 1 
ATOM   2584 N N   . ILE   A 1 363 ? 73.627  95.613  105.986 1.00 106.87 ? 363 ILE   A N   1 
ATOM   2585 C CA  . ILE   A 1 363 ? 72.208  95.939  105.901 1.00 106.87 ? 363 ILE   A CA  1 
ATOM   2586 C C   . ILE   A 1 363 ? 71.332  95.045  106.783 1.00 106.87 ? 363 ILE   A C   1 
ATOM   2587 O O   . ILE   A 1 363 ? 70.337  95.519  107.340 1.00 106.87 ? 363 ILE   A O   1 
ATOM   2588 C CB  . ILE   A 1 363 ? 71.759  95.902  104.425 1.00 106.87 ? 363 ILE   A CB  1 
ATOM   2589 C CG1 . ILE   A 1 363 ? 70.314  96.384  104.266 1.00 106.87 ? 363 ILE   A CG1 1 
ATOM   2590 C CG2 . ILE   A 1 363 ? 71.961  94.526  103.814 1.00 106.87 ? 363 ILE   A CG2 1 
ATOM   2591 C CD1 . ILE   A 1 363 ? 70.148  97.877  104.390 1.00 106.87 ? 363 ILE   A CD1 1 
ATOM   2592 N N   . TYR   A 1 364 ? 71.682  93.768  106.954 1.00 109.35 ? 364 TYR   A N   1 
ATOM   2593 C CA  . TYR   A 1 364 ? 70.779  92.866  107.662 1.00 109.35 ? 364 TYR   A CA  1 
ATOM   2594 C C   . TYR   A 1 364 ? 70.958  92.961  109.173 1.00 109.35 ? 364 TYR   A C   1 
ATOM   2595 O O   . TYR   A 1 364 ? 69.973  93.051  109.914 1.00 109.35 ? 364 TYR   A O   1 
ATOM   2596 C CB  . TYR   A 1 364 ? 70.986  91.425  107.185 1.00 109.35 ? 364 TYR   A CB  1 
ATOM   2597 C CG  . TYR   A 1 364 ? 69.858  90.488  107.575 1.00 109.35 ? 364 TYR   A CG  1 
ATOM   2598 C CD1 . TYR   A 1 364 ? 69.799  89.919  108.843 1.00 109.35 ? 364 TYR   A CD1 1 
ATOM   2599 C CD2 . TYR   A 1 364 ? 68.845  90.184  106.675 1.00 109.35 ? 364 TYR   A CD2 1 
ATOM   2600 C CE1 . TYR   A 1 364 ? 68.766  89.074  109.201 1.00 109.35 ? 364 TYR   A CE1 1 
ATOM   2601 C CE2 . TYR   A 1 364 ? 67.809  89.337  107.023 1.00 109.35 ? 364 TYR   A CE2 1 
ATOM   2602 C CZ  . TYR   A 1 364 ? 67.775  88.786  108.287 1.00 109.35 ? 364 TYR   A CZ  1 
ATOM   2603 O OH  . TYR   A 1 364 ? 66.747  87.941  108.637 1.00 109.35 ? 364 TYR   A OH  1 
ATOM   2604 N N   . GLN   A 1 365 ? 72.205  92.922  109.648 1.00 110.47 ? 365 GLN   A N   1 
ATOM   2605 C CA  . GLN   A 1 365 ? 72.449  92.875  111.087 1.00 110.47 ? 365 GLN   A CA  1 
ATOM   2606 C C   . GLN   A 1 365 ? 72.050  94.178  111.771 1.00 110.47 ? 365 GLN   A C   1 
ATOM   2607 O O   . GLN   A 1 365 ? 71.493  94.159  112.875 1.00 110.47 ? 365 GLN   A O   1 
ATOM   2608 C CB  . GLN   A 1 365 ? 73.918  92.557  111.361 1.00 110.47 ? 365 GLN   A CB  1 
ATOM   2609 C CG  . GLN   A 1 365 ? 74.238  92.332  112.830 1.00 110.47 ? 365 GLN   A CG  1 
ATOM   2610 C CD  . GLN   A 1 365 ? 75.671  91.897  113.054 1.00 110.47 ? 365 GLN   A CD  1 
ATOM   2611 O OE1 . GLN   A 1 365 ? 76.444  91.755  112.107 1.00 110.47 ? 365 GLN   A OE1 1 
ATOM   2612 N NE2 . GLN   A 1 365 ? 76.034  91.681  114.313 1.00 110.47 ? 365 GLN   A NE2 1 
ATOM   2613 N N   . LEU   A 1 366 ? 72.314  95.317  111.132 1.00 110.83 ? 366 LEU   A N   1 
ATOM   2614 C CA  . LEU   A 1 366 ? 72.107  96.619  111.757 1.00 110.83 ? 366 LEU   A CA  1 
ATOM   2615 C C   . LEU   A 1 366 ? 70.855  97.321  111.239 1.00 110.83 ? 366 LEU   A C   1 
ATOM   2616 O O   . LEU   A 1 366 ? 69.979  97.692  112.026 1.00 110.83 ? 366 LEU   A O   1 
ATOM   2617 C CB  . LEU   A 1 366 ? 73.344  97.500  111.539 1.00 110.83 ? 366 LEU   A CB  1 
ATOM   2618 C CG  . LEU   A 1 366 ? 74.625  97.008  112.214 1.00 110.83 ? 366 LEU   A CG  1 
ATOM   2619 C CD1 . LEU   A 1 366 ? 75.803  97.900  111.854 1.00 110.83 ? 366 LEU   A CD1 1 
ATOM   2620 C CD2 . LEU   A 1 366 ? 74.440  96.934  113.723 1.00 110.83 ? 366 LEU   A CD2 1 
ATOM   2621 N N   . SER   A 1 367 ? 70.756  97.513  109.922 1.00 112.71 ? 367 SER   A N   1 
ATOM   2622 C CA  . SER   A 1 367 ? 69.620  98.246  109.372 1.00 112.71 ? 367 SER   A CA  1 
ATOM   2623 C C   . SER   A 1 367 ? 68.345  97.412  109.410 1.00 112.71 ? 367 SER   A C   1 
ATOM   2624 O O   . SER   A 1 367 ? 67.271  97.927  109.744 1.00 112.71 ? 367 SER   A O   1 
ATOM   2625 C CB  . SER   A 1 367 ? 69.927  98.696  107.945 1.00 112.71 ? 367 SER   A CB  1 
ATOM   2626 O OG  . SER   A 1 367 ? 68.841  99.421  107.394 1.00 112.71 ? 367 SER   A OG  1 
ATOM   2627 N N   . PHE   A 1 368 ? 68.438  96.130  109.073 1.00 112.62 ? 368 PHE   A N   1 
ATOM   2628 C CA  . PHE   A 1 368 ? 67.267  95.260  109.070 1.00 112.62 ? 368 PHE   A CA  1 
ATOM   2629 C C   . PHE   A 1 368 ? 67.181  94.458  110.364 1.00 112.62 ? 368 PHE   A C   1 
ATOM   2630 O O   . PHE   A 1 368 ? 66.091  94.136  110.834 1.00 112.62 ? 368 PHE   A O   1 
ATOM   2631 C CB  . PHE   A 1 368 ? 67.296  94.315  107.866 1.00 112.62 ? 368 PHE   A CB  1 
ATOM   2632 C CG  . PHE   A 1 368 ? 67.008  94.990  106.552 1.00 112.62 ? 368 PHE   A CG  1 
ATOM   2633 C CD1 . PHE   A 1 368 ? 66.475  96.269  106.511 1.00 112.62 ? 368 PHE   A CD1 1 
ATOM   2634 C CD2 . PHE   A 1 368 ? 67.269  94.341  105.356 1.00 112.62 ? 368 PHE   A CD2 1 
ATOM   2635 C CE1 . PHE   A 1 368 ? 66.211  96.888  105.303 1.00 112.62 ? 368 PHE   A CE1 1 
ATOM   2636 C CE2 . PHE   A 1 368 ? 67.005  94.953  104.144 1.00 112.62 ? 368 PHE   A CE2 1 
ATOM   2637 C CZ  . PHE   A 1 368 ? 66.476  96.229  104.118 1.00 112.62 ? 368 PHE   A CZ  1 
ATOM   2638 N N   . SER   A 1 373 ? 71.803  87.576  116.799 1.00 117.05 ? 373 SER   A N   1 
ATOM   2639 C CA  . SER   A 1 373 ? 72.148  86.175  117.013 1.00 117.05 ? 373 SER   A CA  1 
ATOM   2640 C C   . SER   A 1 373 ? 73.097  85.679  115.928 1.00 117.05 ? 373 SER   A C   1 
ATOM   2641 O O   . SER   A 1 373 ? 72.854  85.888  114.741 1.00 117.05 ? 373 SER   A O   1 
ATOM   2642 C CB  . SER   A 1 373 ? 70.887  85.311  117.048 1.00 117.05 ? 373 SER   A CB  1 
ATOM   2643 O OG  . SER   A 1 373 ? 69.982  85.769  118.037 1.00 117.05 ? 373 SER   A OG  1 
ATOM   2644 N N   . ASP   A 1 374 ? 74.180  85.018  116.347 1.00 115.41 ? 374 ASP   A N   1 
ATOM   2645 C CA  . ASP   A 1 374 ? 75.164  84.520  115.391 1.00 115.41 ? 374 ASP   A CA  1 
ATOM   2646 C C   . ASP   A 1 374 ? 74.605  83.380  114.547 1.00 115.41 ? 374 ASP   A C   1 
ATOM   2647 O O   . ASP   A 1 374 ? 74.967  83.248  113.371 1.00 115.41 ? 374 ASP   A O   1 
ATOM   2648 C CB  . ASP   A 1 374 ? 76.427  84.070  116.125 1.00 115.41 ? 374 ASP   A CB  1 
ATOM   2649 C CG  . ASP   A 1 374 ? 77.604  83.873  115.191 1.00 115.41 ? 374 ASP   A CG  1 
ATOM   2650 O OD1 . ASP   A 1 374 ? 77.683  84.593  114.173 1.00 115.41 ? 374 ASP   A OD1 1 
ATOM   2651 O OD2 . ASP   A 1 374 ? 78.451  83.000  115.474 1.00 115.41 ? 374 ASP   A OD2 1 
ATOM   2652 N N   . LYS   A 1 375 ? 73.738  82.546  115.128 1.00 113.63 ? 375 LYS   A N   1 
ATOM   2653 C CA  . LYS   A 1 375 ? 73.091  81.487  114.358 1.00 113.63 ? 375 LYS   A CA  1 
ATOM   2654 C C   . LYS   A 1 375 ? 72.212  82.070  113.259 1.00 113.63 ? 375 LYS   A C   1 
ATOM   2655 O O   . LYS   A 1 375 ? 72.176  81.549  112.136 1.00 113.63 ? 375 LYS   A O   1 
ATOM   2656 C CB  . LYS   A 1 375 ? 72.268  80.595  115.287 1.00 113.63 ? 375 LYS   A CB  1 
ATOM   2657 C CG  . LYS   A 1 375 ? 73.076  79.941  116.396 1.00 113.63 ? 375 LYS   A CG  1 
ATOM   2658 C CD  . LYS   A 1 375 ? 72.306  78.803  117.044 1.00 113.63 ? 375 LYS   A CD  1 
ATOM   2659 C CE  . LYS   A 1 375 ? 73.193  78.000  117.981 1.00 113.63 ? 375 LYS   A CE  1 
ATOM   2660 N NZ  . LYS   A 1 375 ? 72.464  76.852  118.586 1.00 113.63 ? 375 LYS   A NZ  1 
ATOM   2661 N N   . GLU   A 1 376 ? 71.497  83.156  113.566 1.00 113.17 ? 376 GLU   A N   1 
ATOM   2662 C CA  . GLU   A 1 376 ? 70.728  83.856  112.544 1.00 113.17 ? 376 GLU   A CA  1 
ATOM   2663 C C   . GLU   A 1 376 ? 71.641  84.425  111.467 1.00 113.17 ? 376 GLU   A C   1 
ATOM   2664 O O   . GLU   A 1 376 ? 71.291  84.417  110.281 1.00 113.17 ? 376 GLU   A O   1 
ATOM   2665 C CB  . GLU   A 1 376 ? 69.893  84.967  113.180 1.00 113.17 ? 376 GLU   A CB  1 
ATOM   2666 C CG  . GLU   A 1 376 ? 68.908  85.624  112.226 1.00 113.17 ? 376 GLU   A CG  1 
ATOM   2667 C CD  . GLU   A 1 376 ? 68.173  86.789  112.857 1.00 113.17 ? 376 GLU   A CD  1 
ATOM   2668 O OE1 . GLU   A 1 376 ? 68.461  87.113  114.028 1.00 113.17 ? 376 GLU   A OE1 1 
ATOM   2669 O OE2 . GLU   A 1 376 ? 67.307  87.384  112.180 1.00 113.17 ? 376 GLU   A OE2 1 
ATOM   2670 N N   . ILE   A 1 377 ? 72.818  84.921  111.861 1.00 109.93 ? 377 ILE   A N   1 
ATOM   2671 C CA  . ILE   A 1 377 ? 73.777  85.439  110.889 1.00 109.93 ? 377 ILE   A CA  1 
ATOM   2672 C C   . ILE   A 1 377 ? 74.234  84.334  109.946 1.00 109.93 ? 377 ILE   A C   1 
ATOM   2673 O O   . ILE   A 1 377 ? 74.307  84.532  108.729 1.00 109.93 ? 377 ILE   A O   1 
ATOM   2674 C CB  . ILE   A 1 377 ? 74.967  86.102  111.609 1.00 109.93 ? 377 ILE   A CB  1 
ATOM   2675 C CG1 . ILE   A 1 377 ? 74.509  87.356  112.354 1.00 109.93 ? 377 ILE   A CG1 1 
ATOM   2676 C CG2 . ILE   A 1 377 ? 76.071  86.454  110.624 1.00 109.93 ? 377 ILE   A CG2 1 
ATOM   2677 C CD1 . ILE   A 1 377 ? 73.899  88.410  111.455 1.00 109.93 ? 377 ILE   A CD1 1 
ATOM   2678 N N   . VAL   A 1 378 ? 74.521  83.147  110.487 1.00 107.28 ? 378 VAL   A N   1 
ATOM   2679 C CA  . VAL   A 1 378 ? 74.940  82.022  109.652 1.00 107.28 ? 378 VAL   A CA  1 
ATOM   2680 C C   . VAL   A 1 378 ? 73.811  81.585  108.720 1.00 107.28 ? 378 VAL   A C   1 
ATOM   2681 O O   . VAL   A 1 378 ? 74.038  81.296  107.537 1.00 107.28 ? 378 VAL   A O   1 
ATOM   2682 C CB  . VAL   A 1 378 ? 75.432  80.862  110.537 1.00 107.28 ? 378 VAL   A CB  1 
ATOM   2683 C CG1 . VAL   A 1 378 ? 75.758  79.637  109.693 1.00 107.28 ? 378 VAL   A CG1 1 
ATOM   2684 C CG2 . VAL   A 1 378 ? 76.648  81.291  111.343 1.00 107.28 ? 378 VAL   A CG2 1 
ATOM   2685 N N   . TRP   A 1 379 ? 72.580  81.528  109.237 1.00 104.81 ? 379 TRP   A N   1 
ATOM   2686 C CA  . TRP   A 1 379 ? 71.442  81.111  108.419 1.00 104.81 ? 379 TRP   A CA  1 
ATOM   2687 C C   . TRP   A 1 379 ? 71.185  82.093  107.277 1.00 104.81 ? 379 TRP   A C   1 
ATOM   2688 O O   . TRP   A 1 379 ? 70.960  81.683  106.129 1.00 104.81 ? 379 TRP   A O   1 
ATOM   2689 C CB  . TRP   A 1 379 ? 70.206  80.967  109.307 1.00 104.81 ? 379 TRP   A CB  1 
ATOM   2690 C CG  . TRP   A 1 379 ? 68.980  80.478  108.607 1.00 104.81 ? 379 TRP   A CG  1 
ATOM   2691 C CD1 . TRP   A 1 379 ? 68.912  79.512  107.647 1.00 104.81 ? 379 TRP   A CD1 1 
ATOM   2692 C CD2 . TRP   A 1 379 ? 67.635  80.918  108.830 1.00 104.81 ? 379 TRP   A CD2 1 
ATOM   2693 N NE1 . TRP   A 1 379 ? 67.609  79.329  107.251 1.00 104.81 ? 379 TRP   A NE1 1 
ATOM   2694 C CE2 . TRP   A 1 379 ? 66.805  80.180  107.964 1.00 104.81 ? 379 TRP   A CE2 1 
ATOM   2695 C CE3 . TRP   A 1 379 ? 67.053  81.867  109.676 1.00 104.81 ? 379 TRP   A CE3 1 
ATOM   2696 C CZ2 . TRP   A 1 379 ? 65.425  80.364  107.917 1.00 104.81 ? 379 TRP   A CZ2 1 
ATOM   2697 C CZ3 . TRP   A 1 379 ? 65.683  82.047  109.629 1.00 104.81 ? 379 TRP   A CZ3 1 
ATOM   2698 C CH2 . TRP   A 1 379 ? 64.885  81.299  108.756 1.00 104.81 ? 379 TRP   A CH2 1 
ATOM   2699 N N   . VAL   A 1 380 ? 71.231  83.395  107.572 1.00 100.11 ? 380 VAL   A N   1 
ATOM   2700 C CA  . VAL   A 1 380 ? 71.042  84.411  106.541 1.00 100.11 ? 380 VAL   A CA  1 
ATOM   2701 C C   . VAL   A 1 380 ? 72.205  84.395  105.556 1.00 100.11 ? 380 VAL   A C   1 
ATOM   2702 O O   . VAL   A 1 380 ? 72.016  84.618  104.356 1.00 100.11 ? 380 VAL   A O   1 
ATOM   2703 C CB  . VAL   A 1 380 ? 70.848  85.792  107.197 1.00 100.11 ? 380 VAL   A CB  1 
ATOM   2704 C CG1 . VAL   A 1 380 ? 70.863  86.909  106.163 1.00 100.11 ? 380 VAL   A CG1 1 
ATOM   2705 C CG2 . VAL   A 1 380 ? 69.540  85.813  107.964 1.00 100.11 ? 380 VAL   A CG2 1 
ATOM   2706 N N   . MET   A 1 381 ? 73.418  84.122  106.044 1.00 97.14  ? 381 MET   A N   1 
ATOM   2707 C CA  . MET   A 1 381 ? 74.573  83.920  105.173 1.00 97.14  ? 381 MET   A CA  1 
ATOM   2708 C C   . MET   A 1 381 ? 74.310  82.816  104.158 1.00 97.14  ? 381 MET   A C   1 
ATOM   2709 O O   . MET   A 1 381 ? 74.518  83.002  102.954 1.00 97.14  ? 381 MET   A O   1 
ATOM   2710 C CB  . MET   A 1 381 ? 75.791  83.585  106.037 1.00 97.14  ? 381 MET   A CB  1 
ATOM   2711 C CG  . MET   A 1 381 ? 77.135  83.479  105.336 1.00 97.14  ? 381 MET   A CG  1 
ATOM   2712 S SD  . MET   A 1 381 ? 77.783  84.995  104.622 1.00 97.14  ? 381 MET   A SD  1 
ATOM   2713 C CE  . MET   A 1 381 ? 78.876  84.302  103.384 1.00 97.14  ? 381 MET   A CE  1 
ATOM   2714 N N   . ARG   A 1 382 ? 73.824  81.666  104.631 1.00 96.75  ? 382 ARG   A N   1 
ATOM   2715 C CA  . ARG   A 1 382 ? 73.528  80.546  103.739 1.00 96.75  ? 382 ARG   A CA  1 
ATOM   2716 C C   . ARG   A 1 382 ? 72.451  80.916  102.721 1.00 96.75  ? 382 ARG   A C   1 
ATOM   2717 O O   . ARG   A 1 382 ? 72.595  80.655  101.515 1.00 96.75  ? 382 ARG   A O   1 
ATOM   2718 C CB  . ARG   A 1 382 ? 73.092  79.335  104.566 1.00 96.75  ? 382 ARG   A CB  1 
ATOM   2719 C CG  . ARG   A 1 382 ? 74.173  78.780  105.483 1.00 96.75  ? 382 ARG   A CG  1 
ATOM   2720 C CD  . ARG   A 1 382 ? 73.694  77.539  106.222 1.00 96.75  ? 382 ARG   A CD  1 
ATOM   2721 N NE  . ARG   A 1 382 ? 72.722  77.864  107.259 1.00 96.75  ? 382 ARG   A NE  1 
ATOM   2722 C CZ  . ARG   A 1 382 ? 72.060  76.965  107.975 1.00 96.75  ? 382 ARG   A CZ  1 
ATOM   2723 N NH1 . ARG   A 1 382 ? 72.243  75.667  107.796 1.00 96.75  ? 382 ARG   A NH1 1 
ATOM   2724 N NH2 . ARG   A 1 382 ? 71.192  77.379  108.895 1.00 96.75  ? 382 ARG   A NH2 1 
ATOM   2725 N N   . ILE   A 1 383 ? 71.371  81.547  103.195 1.00 88.70  ? 383 ILE   A N   1 
ATOM   2726 C CA  . ILE   A 1 383 ? 70.260  81.905  102.314 1.00 88.70  ? 383 ILE   A CA  1 
ATOM   2727 C C   . ILE   A 1 383 ? 70.709  82.899  101.250 1.00 88.70  ? 383 ILE   A C   1 
ATOM   2728 O O   . ILE   A 1 383 ? 70.382  82.751  100.065 1.00 88.70  ? 383 ILE   A O   1 
ATOM   2729 C CB  . ILE   A 1 383 ? 69.080  82.455  103.137 1.00 88.70  ? 383 ILE   A CB  1 
ATOM   2730 C CG1 . ILE   A 1 383 ? 68.465  81.354  103.998 1.00 88.70  ? 383 ILE   A CG1 1 
ATOM   2731 C CG2 . ILE   A 1 383 ? 68.022  83.068  102.231 1.00 88.70  ? 383 ILE   A CG2 1 
ATOM   2732 C CD1 . ILE   A 1 383 ? 67.439  81.865  104.976 1.00 88.70  ? 383 ILE   A CD1 1 
ATOM   2733 N N   . THR   A 1 384 ? 71.473  83.921  101.646 1.00 81.29  ? 384 THR   A N   1 
ATOM   2734 C CA  . THR   A 1 384 ? 71.872  84.942  100.687 1.00 81.29  ? 384 THR   A CA  1 
ATOM   2735 C C   . THR   A 1 384 ? 72.938  84.428  99.728  1.00 81.29  ? 384 THR   A C   1 
ATOM   2736 O O   . THR   A 1 384 ? 72.969  84.861  98.573  1.00 81.29  ? 384 THR   A O   1 
ATOM   2737 C CB  . THR   A 1 384 ? 72.331  86.216  101.412 1.00 81.29  ? 384 THR   A CB  1 
ATOM   2738 O OG1 . THR   A 1 384 ? 72.350  87.312  100.488 1.00 81.29  ? 384 THR   A OG1 1 
ATOM   2739 C CG2 . THR   A 1 384 ? 73.711  86.063  102.028 1.00 81.29  ? 384 THR   A CG2 1 
ATOM   2740 N N   . VAL   A 1 385 ? 73.780  83.476  100.153 1.00 77.25  ? 385 VAL   A N   1 
ATOM   2741 C CA  . VAL   A 1 385 ? 74.680  82.824  99.205  1.00 77.25  ? 385 VAL   A CA  1 
ATOM   2742 C C   . VAL   A 1 385 ? 73.884  82.062  98.157  1.00 77.25  ? 385 VAL   A C   1 
ATOM   2743 O O   . VAL   A 1 385 ? 74.168  82.157  96.955  1.00 77.25  ? 385 VAL   A O   1 
ATOM   2744 C CB  . VAL   A 1 385 ? 75.679  81.907  99.937  1.00 77.25  ? 385 VAL   A CB  1 
ATOM   2745 C CG1 . VAL   A 1 385 ? 76.417  81.035  98.943  1.00 77.25  ? 385 VAL   A CG1 1 
ATOM   2746 C CG2 . VAL   A 1 385 ? 76.695  82.739  100.691 1.00 77.25  ? 385 VAL   A CG2 1 
ATOM   2747 N N   . PHE   A 1 386 ? 72.858  81.318  98.586  1.00 75.50  ? 386 PHE   A N   1 
ATOM   2748 C CA  . PHE   A 1 386 ? 72.054  80.569  97.622  1.00 75.50  ? 386 PHE   A CA  1 
ATOM   2749 C C   . PHE   A 1 386 ? 71.325  81.498  96.653  1.00 75.50  ? 386 PHE   A C   1 
ATOM   2750 O O   . PHE   A 1 386 ? 71.322  81.259  95.438  1.00 75.50  ? 386 PHE   A O   1 
ATOM   2751 C CB  . PHE   A 1 386 ? 71.057  79.667  98.347  1.00 75.50  ? 386 PHE   A CB  1 
ATOM   2752 C CG  . PHE   A 1 386 ? 70.228  78.823  97.422  1.00 75.50  ? 386 PHE   A CG  1 
ATOM   2753 C CD1 . PHE   A 1 386 ? 70.758  77.679  96.848  1.00 75.50  ? 386 PHE   A CD1 1 
ATOM   2754 C CD2 . PHE   A 1 386 ? 68.921  79.173  97.124  1.00 75.50  ? 386 PHE   A CD2 1 
ATOM   2755 C CE1 . PHE   A 1 386 ? 70.001  76.902  95.994  1.00 75.50  ? 386 PHE   A CE1 1 
ATOM   2756 C CE2 . PHE   A 1 386 ? 68.159  78.399  96.271  1.00 75.50  ? 386 PHE   A CE2 1 
ATOM   2757 C CZ  . PHE   A 1 386 ? 68.700  77.262  95.705  1.00 75.50  ? 386 PHE   A CZ  1 
ATOM   2758 N N   . VAL   A 1 387 ? 70.716  82.569  97.170  1.00 69.10  ? 387 VAL   A N   1 
ATOM   2759 C CA  . VAL   A 1 387 ? 69.961  83.486  96.317  1.00 69.10  ? 387 VAL   A CA  1 
ATOM   2760 C C   . VAL   A 1 387 ? 70.889  84.225  95.359  1.00 69.10  ? 387 VAL   A C   1 
ATOM   2761 O O   . VAL   A 1 387 ? 70.572  84.391  94.173  1.00 69.10  ? 387 VAL   A O   1 
ATOM   2762 C CB  . VAL   A 1 387 ? 69.132  84.460  97.175  1.00 69.10  ? 387 VAL   A CB  1 
ATOM   2763 C CG1 . VAL   A 1 387 ? 68.432  85.484  96.299  1.00 69.10  ? 387 VAL   A CG1 1 
ATOM   2764 C CG2 . VAL   A 1 387 ? 68.101  83.695  97.987  1.00 69.10  ? 387 VAL   A CG2 1 
ATOM   2765 N N   . PHE   A 1 388 ? 72.047  84.679  95.851  1.00 65.56  ? 388 PHE   A N   1 
ATOM   2766 C CA  . PHE   A 1 388 ? 73.013  85.360  94.999  1.00 65.56  ? 388 PHE   A CA  1 
ATOM   2767 C C   . PHE   A 1 388 ? 73.528  84.440  93.902  1.00 65.56  ? 388 PHE   A C   1 
ATOM   2768 O O   . PHE   A 1 388 ? 73.648  84.856  92.745  1.00 65.56  ? 388 PHE   A O   1 
ATOM   2769 C CB  . PHE   A 1 388 ? 74.167  85.883  95.853  1.00 65.56  ? 388 PHE   A CB  1 
ATOM   2770 C CG  . PHE   A 1 388 ? 75.163  86.708  95.095  1.00 65.56  ? 388 PHE   A CG  1 
ATOM   2771 C CD1 . PHE   A 1 388 ? 74.904  88.037  94.808  1.00 65.56  ? 388 PHE   A CD1 1 
ATOM   2772 C CD2 . PHE   A 1 388 ? 76.362  86.157  94.676  1.00 65.56  ? 388 PHE   A CD2 1 
ATOM   2773 C CE1 . PHE   A 1 388 ? 75.820  88.799  94.115  1.00 65.56  ? 388 PHE   A CE1 1 
ATOM   2774 C CE2 . PHE   A 1 388 ? 77.281  86.913  93.982  1.00 65.56  ? 388 PHE   A CE2 1 
ATOM   2775 C CZ  . PHE   A 1 388 ? 77.010  88.236  93.702  1.00 65.56  ? 388 PHE   A CZ  1 
ATOM   2776 N N   . GLY   A 1 389 ? 73.824  83.182  94.242  1.00 58.51  ? 389 GLY   A N   1 
ATOM   2777 C CA  . GLY   A 1 389 ? 74.272  82.240  93.230  1.00 58.51  ? 389 GLY   A CA  1 
ATOM   2778 C C   . GLY   A 1 389 ? 73.213  81.953  92.183  1.00 58.51  ? 389 GLY   A C   1 
ATOM   2779 O O   . GLY   A 1 389 ? 73.514  81.886  90.988  1.00 58.51  ? 389 GLY   A O   1 
ATOM   2780 N N   . ALA   A 1 390 ? 71.957  81.790  92.614  1.00 58.68  ? 390 ALA   A N   1 
ATOM   2781 C CA  . ALA   A 1 390 ? 70.876  81.532  91.666  1.00 58.68  ? 390 ALA   A CA  1 
ATOM   2782 C C   . ALA   A 1 390 ? 70.648  82.721  90.738  1.00 58.68  ? 390 ALA   A C   1 
ATOM   2783 O O   . ALA   A 1 390 ? 70.476  82.546  89.524  1.00 58.68  ? 390 ALA   A O   1 
ATOM   2784 C CB  . ALA   A 1 390 ? 69.592  81.183  92.416  1.00 58.68  ? 390 ALA   A CB  1 
ATOM   2785 N N   . SER   A 1 391 ? 70.651  83.938  91.286  1.00 54.30  ? 391 SER   A N   1 
ATOM   2786 C CA  . SER   A 1 391 ? 70.473  85.120  90.448  1.00 54.30  ? 391 SER   A CA  1 
ATOM   2787 C C   . SER   A 1 391 ? 71.641  85.299  89.486  1.00 54.30  ? 391 SER   A C   1 
ATOM   2788 O O   . SER   A 1 391 ? 71.438  85.636  88.312  1.00 54.30  ? 391 SER   A O   1 
ATOM   2789 C CB  . SER   A 1 391 ? 70.299  86.361  91.319  1.00 54.30  ? 391 SER   A CB  1 
ATOM   2790 O OG  . SER   A 1 391 ? 70.140  87.516  90.517  1.00 54.30  ? 391 SER   A OG  1 
ATOM   2791 N N   . ALA   A 1 392 ? 72.869  85.063  89.960  1.00 49.35  ? 392 ALA   A N   1 
ATOM   2792 C CA  . ALA   A 1 392 ? 74.039  85.196  89.102  1.00 49.35  ? 392 ALA   A CA  1 
ATOM   2793 C C   . ALA   A 1 392 ? 74.031  84.168  87.979  1.00 49.35  ? 392 ALA   A C   1 
ATOM   2794 O O   . ALA   A 1 392 ? 74.374  84.494  86.839  1.00 49.35  ? 392 ALA   A O   1 
ATOM   2795 C CB  . ALA   A 1 392 ? 75.314  85.073  89.932  1.00 49.35  ? 392 ALA   A CB  1 
ATOM   2796 N N   . THR   A 1 393 ? 73.630  82.925  88.266  1.00 50.41  ? 393 THR   A N   1 
ATOM   2797 C CA  . THR   A 1 393 ? 73.620  81.936  87.194  1.00 50.41  ? 393 THR   A CA  1 
ATOM   2798 C C   . THR   A 1 393 ? 72.461  82.151  86.227  1.00 50.41  ? 393 THR   A C   1 
ATOM   2799 O O   . THR   A 1 393 ? 72.617  81.891  85.030  1.00 50.41  ? 393 THR   A O   1 
ATOM   2800 C CB  . THR   A 1 393 ? 73.612  80.507  87.756  1.00 50.41  ? 393 THR   A CB  1 
ATOM   2801 O OG1 . THR   A 1 393 ? 73.777  79.574  86.682  1.00 50.41  ? 393 THR   A OG1 1 
ATOM   2802 C CG2 . THR   A 1 393 ? 72.327  80.182  88.483  1.00 50.41  ? 393 THR   A CG2 1 
ATOM   2803 N N   . ALA   A 1 394 ? 71.317  82.665  86.696  1.00 50.29  ? 394 ALA   A N   1 
ATOM   2804 C CA  . ALA   A 1 394 ? 70.258  83.031  85.760  1.00 50.29  ? 394 ALA   A CA  1 
ATOM   2805 C C   . ALA   A 1 394 ? 70.703  84.168  84.849  1.00 50.29  ? 394 ALA   A C   1 
ATOM   2806 O O   . ALA   A 1 394 ? 70.494  84.117  83.629  1.00 50.29  ? 394 ALA   A O   1 
ATOM   2807 C CB  . ALA   A 1 394 ? 68.991  83.413  86.521  1.00 50.29  ? 394 ALA   A CB  1 
ATOM   2808 N N   . MET   A 1 395 ? 71.353  85.183  85.422  1.00 51.36  ? 395 MET   A N   1 
ATOM   2809 C CA  . MET   A 1 395 ? 71.844  86.303  84.629  1.00 51.36  ? 395 MET   A CA  1 
ATOM   2810 C C   . MET   A 1 395 ? 72.931  85.860  83.656  1.00 51.36  ? 395 MET   A C   1 
ATOM   2811 O O   . MET   A 1 395 ? 73.031  86.393  82.548  1.00 51.36  ? 395 MET   A O   1 
ATOM   2812 C CB  . MET   A 1 395 ? 72.353  87.397  85.562  1.00 51.36  ? 395 MET   A CB  1 
ATOM   2813 C CG  . MET   A 1 395 ? 72.785  88.674  84.889  1.00 51.36  ? 395 MET   A CG  1 
ATOM   2814 S SD  . MET   A 1 395 ? 73.334  89.834  86.145  1.00 51.36  ? 395 MET   A SD  1 
ATOM   2815 C CE  . MET   A 1 395 ? 71.771  90.275  86.896  1.00 51.36  ? 395 MET   A CE  1 
ATOM   2816 N N   . ALA   A 1 396 ? 73.750  84.882  84.051  1.00 47.08  ? 396 ALA   A N   1 
ATOM   2817 C CA  . ALA   A 1 396 ? 74.721  84.309  83.125  1.00 47.08  ? 396 ALA   A CA  1 
ATOM   2818 C C   . ALA   A 1 396 ? 74.034  83.536  82.007  1.00 47.08  ? 396 ALA   A C   1 
ATOM   2819 O O   . ALA   A 1 396 ? 74.525  83.510  80.873  1.00 47.08  ? 396 ALA   A O   1 
ATOM   2820 C CB  . ALA   A 1 396 ? 75.695  83.405  83.879  1.00 47.08  ? 396 ALA   A CB  1 
ATOM   2821 N N   . LEU   A 1 397 ? 72.911  82.881  82.313  1.00 48.38  ? 397 LEU   A N   1 
ATOM   2822 C CA  . LEU   A 1 397 ? 72.180  82.145  81.284  1.00 48.38  ? 397 LEU   A CA  1 
ATOM   2823 C C   . LEU   A 1 397 ? 71.563  83.081  80.251  1.00 48.38  ? 397 LEU   A C   1 
ATOM   2824 O O   . LEU   A 1 397 ? 71.584  82.784  79.051  1.00 48.38  ? 397 LEU   A O   1 
ATOM   2825 C CB  . LEU   A 1 397 ? 71.098  81.273  81.920  1.00 48.38  ? 397 LEU   A CB  1 
ATOM   2826 C CG  . LEU   A 1 397 ? 71.563  80.001  82.627  1.00 48.38  ? 397 LEU   A CG  1 
ATOM   2827 C CD1 . LEU   A 1 397 ? 70.442  79.419  83.471  1.00 48.38  ? 397 LEU   A CD1 1 
ATOM   2828 C CD2 . LEU   A 1 397 ? 72.071  78.986  81.626  1.00 48.38  ? 397 LEU   A CD2 1 
ATOM   2829 N N   . LEU   A 1 398 ? 70.998  84.210  80.692  1.00 47.90  ? 398 LEU   A N   1 
ATOM   2830 C CA  . LEU   A 1 398 ? 70.344  85.110  79.741  1.00 47.90  ? 398 LEU   A CA  1 
ATOM   2831 C C   . LEU   A 1 398 ? 71.341  85.819  78.825  1.00 47.90  ? 398 LEU   A C   1 
ATOM   2832 O O   . LEU   A 1 398 ? 71.074  85.981  77.629  1.00 47.90  ? 398 LEU   A O   1 
ATOM   2833 C CB  . LEU   A 1 398 ? 69.465  86.132  80.467  1.00 47.90  ? 398 LEU   A CB  1 
ATOM   2834 C CG  . LEU   A 1 398 ? 68.032  85.761  80.884  1.00 47.90  ? 398 LEU   A CG  1 
ATOM   2835 C CD1 . LEU   A 1 398 ? 67.197  85.494  79.643  1.00 47.90  ? 398 LEU   A CD1 1 
ATOM   2836 C CD2 . LEU   A 1 398 ? 67.929  84.580  81.826  1.00 47.90  ? 398 LEU   A CD2 1 
ATOM   2837 N N   . THR   A 1 399 ? 72.483  86.252  79.352  1.00 48.83  ? 399 THR   A N   1 
ATOM   2838 C CA  . THR   A 1 399 ? 73.390  87.057  78.545  1.00 48.83  ? 399 THR   A CA  1 
ATOM   2839 C C   . THR   A 1 399 ? 74.215  86.189  77.595  1.00 48.83  ? 399 THR   A C   1 
ATOM   2840 O O   . THR   A 1 399 ? 74.275  84.963  77.711  1.00 48.83  ? 399 THR   A O   1 
ATOM   2841 C CB  . THR   A 1 399 ? 74.322  87.883  79.428  1.00 48.83  ? 399 THR   A CB  1 
ATOM   2842 O OG1 . THR   A 1 399 ? 75.211  87.009  80.133  1.00 48.83  ? 399 THR   A OG1 1 
ATOM   2843 C CG2 . THR   A 1 399 ? 73.526  88.725  80.410  1.00 48.83  ? 399 THR   A CG2 1 
ATOM   2844 N N   . LYS   A 1 400 ? 74.865  86.861  76.640  1.00 49.80  ? 400 LYS   A N   1 
ATOM   2845 C CA  . LYS   A 1 400 ? 75.667  86.205  75.615  1.00 49.80  ? 400 LYS   A CA  1 
ATOM   2846 C C   . LYS   A 1 400 ? 77.094  86.737  75.552  1.00 49.80  ? 400 LYS   A C   1 
ATOM   2847 O O   . LYS   A 1 400 ? 77.794  86.473  74.568  1.00 49.80  ? 400 LYS   A O   1 
ATOM   2848 C CB  . LYS   A 1 400 ? 75.007  86.357  74.238  1.00 49.80  ? 400 LYS   A CB  1 
ATOM   2849 C CG  . LYS   A 1 400 ? 73.640  85.706  74.115  1.00 49.80  ? 400 LYS   A CG  1 
ATOM   2850 C CD  . LYS   A 1 400 ? 73.728  84.195  74.246  1.00 49.80  ? 400 LYS   A CD  1 
ATOM   2851 C CE  . LYS   A 1 400 ? 74.384  83.574  73.024  1.00 49.80  ? 400 LYS   A CE  1 
ATOM   2852 N NZ  . LYS   A 1 400 ? 74.408  82.088  73.104  1.00 49.80  ? 400 LYS   A NZ  1 
ATOM   2853 N N   . THR   A 1 401 ? 77.545  87.477  76.563  1.00 45.01  ? 401 THR   A N   1 
ATOM   2854 C CA  . THR   A 1 401 ? 78.872  88.073  76.544  1.00 45.01  ? 401 THR   A CA  1 
ATOM   2855 C C   . THR   A 1 401 ? 79.459  88.093  77.947  1.00 45.01  ? 401 THR   A C   1 
ATOM   2856 O O   . THR   A 1 401 ? 78.734  88.090  78.945  1.00 45.01  ? 401 THR   A O   1 
ATOM   2857 C CB  . THR   A 1 401 ? 78.840  89.497  75.973  1.00 45.01  ? 401 THR   A CB  1 
ATOM   2858 O OG1 . THR   A 1 401 ? 80.163  90.044  75.970  1.00 45.01  ? 401 THR   A OG1 1 
ATOM   2859 C CG2 . THR   A 1 401 ? 77.924  90.385  76.795  1.00 45.01  ? 401 THR   A CG2 1 
ATOM   2860 N N   . VAL   A 1 402 ? 80.787  88.099  78.009  1.00 39.49  ? 402 VAL   A N   1 
ATOM   2861 C CA  . VAL   A 1 402 ? 81.511  88.210  79.267  1.00 39.49  ? 402 VAL   A CA  1 
ATOM   2862 C C   . VAL   A 1 402 ? 82.025  89.627  79.491  1.00 39.49  ? 402 VAL   A C   1 
ATOM   2863 O O   . VAL   A 1 402 ? 81.881  90.176  80.584  1.00 39.49  ? 402 VAL   A O   1 
ATOM   2864 C CB  . VAL   A 1 402 ? 82.665  87.185  79.309  1.00 39.49  ? 402 VAL   A CB  1 
ATOM   2865 C CG1 . VAL   A 1 402 ? 83.477  87.340  80.582  1.00 39.49  ? 402 VAL   A CG1 1 
ATOM   2866 C CG2 . VAL   A 1 402 ? 82.123  85.773  79.190  1.00 39.49  ? 402 VAL   A CG2 1 
ATOM   2867 N N   . TYR   A 1 403 ? 82.616  90.235  78.458  1.00 38.25  ? 403 TYR   A N   1 
ATOM   2868 C CA  . TYR   A 1 403 ? 83.101  91.605  78.585  1.00 38.25  ? 403 TYR   A CA  1 
ATOM   2869 C C   . TYR   A 1 403 ? 81.955  92.594  78.745  1.00 38.25  ? 403 TYR   A C   1 
ATOM   2870 O O   . TYR   A 1 403 ? 82.128  93.628  79.395  1.00 38.25  ? 403 TYR   A O   1 
ATOM   2871 C CB  . TYR   A 1 403 ? 83.961  91.982  77.378  1.00 38.25  ? 403 TYR   A CB  1 
ATOM   2872 C CG  . TYR   A 1 403 ? 84.719  93.287  77.540  1.00 38.25  ? 403 TYR   A CG  1 
ATOM   2873 C CD1 . TYR   A 1 403 ? 84.132  94.506  77.228  1.00 38.25  ? 403 TYR   A CD1 1 
ATOM   2874 C CD2 . TYR   A 1 403 ? 86.023  93.296  78.007  1.00 38.25  ? 403 TYR   A CD2 1 
ATOM   2875 C CE1 . TYR   A 1 403 ? 84.817  95.689  77.377  1.00 38.25  ? 403 TYR   A CE1 1 
ATOM   2876 C CE2 . TYR   A 1 403 ? 86.719  94.476  78.153  1.00 38.25  ? 403 TYR   A CE2 1 
ATOM   2877 C CZ  . TYR   A 1 403 ? 86.109  95.669  77.839  1.00 38.25  ? 403 TYR   A CZ  1 
ATOM   2878 O OH  . TYR   A 1 403 ? 86.793  96.850  77.985  1.00 38.25  ? 403 TYR   A OH  1 
ATOM   2879 N N   . GLY   A 1 404 ? 80.792  92.311  78.158  1.00 42.53  ? 404 GLY   A N   1 
ATOM   2880 C CA  . GLY   A 1 404 ? 79.655  93.199  78.343  1.00 42.53  ? 404 GLY   A CA  1 
ATOM   2881 C C   . GLY   A 1 404 ? 79.203  93.260  79.788  1.00 42.53  ? 404 GLY   A C   1 
ATOM   2882 O O   . GLY   A 1 404 ? 78.966  94.340  80.334  1.00 42.53  ? 404 GLY   A O   1 
ATOM   2883 N N   . LEU   A 1 405 ? 79.095  92.097  80.433  1.00 40.48  ? 405 LEU   A N   1 
ATOM   2884 C CA  . LEU   A 1 405 ? 78.783  92.057  81.857  1.00 40.48  ? 405 LEU   A CA  1 
ATOM   2885 C C   . LEU   A 1 405 ? 79.904  92.676  82.679  1.00 40.48  ? 405 LEU   A C   1 
ATOM   2886 O O   . LEU   A 1 405 ? 79.649  93.355  83.678  1.00 40.48  ? 405 LEU   A O   1 
ATOM   2887 C CB  . LEU   A 1 405 ? 78.534  90.617  82.298  1.00 40.48  ? 405 LEU   A CB  1 
ATOM   2888 C CG  . LEU   A 1 405 ? 77.245  89.958  81.816  1.00 40.48  ? 405 LEU   A CG  1 
ATOM   2889 C CD1 . LEU   A 1 405 ? 77.236  88.495  82.209  1.00 40.48  ? 405 LEU   A CD1 1 
ATOM   2890 C CD2 . LEU   A 1 405 ? 76.035  90.677  82.376  1.00 40.48  ? 405 LEU   A CD2 1 
ATOM   2891 N N   . TRP   A 1 406 ? 81.152  92.456  82.257  1.00 40.22  ? 406 TRP   A N   1 
ATOM   2892 C CA  . TRP   A 1 406 ? 82.306  93.026  82.946  1.00 40.22  ? 406 TRP   A CA  1 
ATOM   2893 C C   . TRP   A 1 406 ? 82.268  94.551  82.932  1.00 40.22  ? 406 TRP   A C   1 
ATOM   2894 O O   . TRP   A 1 406 ? 82.561  95.198  83.944  1.00 40.22  ? 406 TRP   A O   1 
ATOM   2895 C CB  . TRP   A 1 406 ? 83.582  92.510  82.282  1.00 40.22  ? 406 TRP   A CB  1 
ATOM   2896 C CG  . TRP   A 1 406 ? 84.814  92.702  83.077  1.00 40.22  ? 406 TRP   A CG  1 
ATOM   2897 C CD1 . TRP   A 1 406 ? 84.893  93.012  84.395  1.00 40.22  ? 406 TRP   A CD1 1 
ATOM   2898 C CD2 . TRP   A 1 406 ? 86.161  92.579  82.610  1.00 40.22  ? 406 TRP   A CD2 1 
ATOM   2899 N NE1 . TRP   A 1 406 ? 86.204  93.089  84.785  1.00 40.22  ? 406 TRP   A NE1 1 
ATOM   2900 C CE2 . TRP   A 1 406 ? 87.005  92.836  83.704  1.00 40.22  ? 406 TRP   A CE2 1 
ATOM   2901 C CE3 . TRP   A 1 406 ? 86.735  92.282  81.372  1.00 40.22  ? 406 TRP   A CE3 1 
ATOM   2902 C CZ2 . TRP   A 1 406 ? 88.390  92.804  83.600  1.00 40.22  ? 406 TRP   A CZ2 1 
ATOM   2903 C CZ3 . TRP   A 1 406 ? 88.111  92.250  81.270  1.00 40.22  ? 406 TRP   A CZ3 1 
ATOM   2904 C CH2 . TRP   A 1 406 ? 88.923  92.509  82.377  1.00 40.22  ? 406 TRP   A CH2 1 
ATOM   2905 N N   . TYR   A 1 407 ? 81.910  95.138  81.790  1.00 42.31  ? 407 TYR   A N   1 
ATOM   2906 C CA  . TYR   A 1 407 ? 81.820  96.589  81.675  1.00 42.31  ? 407 TYR   A CA  1 
ATOM   2907 C C   . TYR   A 1 407 ? 80.601  97.126  82.412  1.00 42.31  ? 407 TYR   A C   1 
ATOM   2908 O O   . TYR   A 1 407 ? 80.686  98.152  83.095  1.00 42.31  ? 407 TYR   A O   1 
ATOM   2909 C CB  . TYR   A 1 407 ? 81.791  96.983  80.194  1.00 42.31  ? 407 TYR   A CB  1 
ATOM   2910 C CG  . TYR   A 1 407 ? 81.560  98.454  79.904  1.00 42.31  ? 407 TYR   A CG  1 
ATOM   2911 C CD1 . TYR   A 1 407 ? 80.275  98.974  79.782  1.00 42.31  ? 407 TYR   A CD1 1 
ATOM   2912 C CD2 . TYR   A 1 407 ? 82.631  99.320  79.737  1.00 42.31  ? 407 TYR   A CD2 1 
ATOM   2913 C CE1 . TYR   A 1 407 ? 80.067  100.311 79.516  1.00 42.31  ? 407 TYR   A CE1 1 
ATOM   2914 C CE2 . TYR   A 1 407 ? 82.431  100.658 79.467  1.00 42.31  ? 407 TYR   A CE2 1 
ATOM   2915 C CZ  . TYR   A 1 407 ? 81.147  101.148 79.358  1.00 42.31  ? 407 TYR   A CZ  1 
ATOM   2916 O OH  . TYR   A 1 407 ? 80.943  102.480 79.090  1.00 42.31  ? 407 TYR   A OH  1 
ATOM   2917 N N   . LEU   A 1 408 ? 79.455  96.452  82.280  1.00 42.84  ? 408 LEU   A N   1 
ATOM   2918 C CA  . LEU   A 1 408 ? 78.229  96.908  82.922  1.00 42.84  ? 408 LEU   A CA  1 
ATOM   2919 C C   . LEU   A 1 408 ? 78.287  96.765  84.438  1.00 42.84  ? 408 LEU   A C   1 
ATOM   2920 O O   . LEU   A 1 408 ? 77.532  97.441  85.144  1.00 42.84  ? 408 LEU   A O   1 
ATOM   2921 C CB  . LEU   A 1 408 ? 77.040  96.134  82.346  1.00 42.84  ? 408 LEU   A CB  1 
ATOM   2922 C CG  . LEU   A 1 408 ? 75.614  96.459  82.787  1.00 42.84  ? 408 LEU   A CG  1 
ATOM   2923 C CD1 . LEU   A 1 408 ? 75.275  97.903  82.468  1.00 42.84  ? 408 LEU   A CD1 1 
ATOM   2924 C CD2 . LEU   A 1 408 ? 74.636  95.518  82.112  1.00 42.84  ? 408 LEU   A CD2 1 
ATOM   2925 N N   . SER   A 1 409 ? 79.175  95.910  84.948  1.00 43.36  ? 409 SER   A N   1 
ATOM   2926 C CA  . SER   A 1 409 ? 79.335  95.768  86.390  1.00 43.36  ? 409 SER   A CA  1 
ATOM   2927 C C   . SER   A 1 409 ? 79.857  97.051  87.022  1.00 43.36  ? 409 SER   A C   1 
ATOM   2928 O O   . SER   A 1 409 ? 79.438  97.425  88.123  1.00 43.36  ? 409 SER   A O   1 
ATOM   2929 C CB  . SER   A 1 409 ? 80.276  94.603  86.685  1.00 43.36  ? 409 SER   A CB  1 
ATOM   2930 O OG  . SER   A 1 409 ? 80.486  94.470  88.073  1.00 43.36  ? 409 SER   A OG  1 
ATOM   2931 N N   . SER   A 1 410 ? 80.778  97.736  86.346  1.00 44.98  ? 410 SER   A N   1 
ATOM   2932 C CA  . SER   A 1 410 ? 81.351  98.967  86.870  1.00 44.98  ? 410 SER   A CA  1 
ATOM   2933 C C   . SER   A 1 410 ? 80.515  100.200 86.559  1.00 44.98  ? 410 SER   A C   1 
ATOM   2934 O O   . SER   A 1 410 ? 80.826  101.276 87.075  1.00 44.98  ? 410 SER   A O   1 
ATOM   2935 C CB  . SER   A 1 410 ? 82.764  99.164  86.318  1.00 44.98  ? 410 SER   A CB  1 
ATOM   2936 O OG  . SER   A 1 410 ? 83.668  98.241  86.894  1.00 44.98  ? 410 SER   A OG  1 
ATOM   2937 N N   . ASP   A 1 411 ? 79.458  100.065 85.753  1.00 46.89  ? 411 ASP   A N   1 
ATOM   2938 C CA  . ASP   A 1 411 ? 78.690  101.223 85.302  1.00 46.89  ? 411 ASP   A CA  1 
ATOM   2939 C C   . ASP   A 1 411 ? 77.986  101.914 86.466  1.00 46.89  ? 411 ASP   A C   1 
ATOM   2940 O O   . ASP   A 1 411 ? 78.199  103.106 86.718  1.00 46.89  ? 411 ASP   A O   1 
ATOM   2941 C CB  . ASP   A 1 411 ? 77.679  100.785 84.240  1.00 46.89  ? 411 ASP   A CB  1 
ATOM   2942 C CG  . ASP   A 1 411 ? 77.182  101.938 83.386  1.00 46.89  ? 411 ASP   A CG  1 
ATOM   2943 O OD1 . ASP   A 1 411 ? 77.383  103.109 83.768  1.00 46.89  ? 411 ASP   A OD1 1 
ATOM   2944 O OD2 . ASP   A 1 411 ? 76.585  101.668 82.324  1.00 46.89  ? 411 ASP   A OD2 1 
ATOM   2945 N N   . LEU   A 1 412 ? 77.137  101.177 87.187  1.00 47.93  ? 412 LEU   A N   1 
ATOM   2946 C CA  . LEU   A 1 412 ? 76.390  101.776 88.289  1.00 47.93  ? 412 LEU   A CA  1 
ATOM   2947 C C   . LEU   A 1 412 ? 77.303  102.162 89.445  1.00 47.93  ? 412 LEU   A C   1 
ATOM   2948 O O   . LEU   A 1 412 ? 76.979  103.080 90.205  1.00 47.93  ? 412 LEU   A O   1 
ATOM   2949 C CB  . LEU   A 1 412 ? 75.296  100.822 88.774  1.00 47.93  ? 412 LEU   A CB  1 
ATOM   2950 C CG  . LEU   A 1 412 ? 73.919  100.878 88.101  1.00 47.93  ? 412 LEU   A CG  1 
ATOM   2951 C CD1 . LEU   A 1 412 ? 73.301  102.258 88.259  1.00 47.93  ? 412 LEU   A CD1 1 
ATOM   2952 C CD2 . LEU   A 1 412 ? 73.965  100.467 86.634  1.00 47.93  ? 412 LEU   A CD2 1 
ATOM   2953 N N   . VAL   A 1 413 ? 78.434  101.473 89.601  1.00 46.52  ? 413 VAL   A N   1 
ATOM   2954 C CA  . VAL   A 1 413 ? 79.407  101.862 90.616  1.00 46.52  ? 413 VAL   A CA  1 
ATOM   2955 C C   . VAL   A 1 413 ? 80.039  103.203 90.259  1.00 46.52  ? 413 VAL   A C   1 
ATOM   2956 O O   . VAL   A 1 413 ? 80.224  104.068 91.123  1.00 46.52  ? 413 VAL   A O   1 
ATOM   2957 C CB  . VAL   A 1 413 ? 80.464  100.756 90.783  1.00 46.52  ? 413 VAL   A CB  1 
ATOM   2958 C CG1 . VAL   A 1 413 ? 81.519  101.168 91.794  1.00 46.52  ? 413 VAL   A CG1 1 
ATOM   2959 C CG2 . VAL   A 1 413 ? 79.803  99.453  91.194  1.00 46.52  ? 413 VAL   A CG2 1 
ATOM   2960 N N   . TYR   A 1 414 ? 80.376  103.396 88.982  1.00 43.89  ? 414 TYR   A N   1 
ATOM   2961 C CA  . TYR   A 1 414 ? 80.952  104.657 88.531  1.00 43.89  ? 414 TYR   A CA  1 
ATOM   2962 C C   . TYR   A 1 414 ? 79.958  105.803 88.647  1.00 43.89  ? 414 TYR   A C   1 
ATOM   2963 O O   . TYR   A 1 414 ? 80.320  106.900 89.086  1.00 43.89  ? 414 TYR   A O   1 
ATOM   2964 C CB  . TYR   A 1 414 ? 81.429  104.507 87.088  1.00 43.89  ? 414 TYR   A CB  1 
ATOM   2965 C CG  . TYR   A 1 414 ? 81.929  105.777 86.443  1.00 43.89  ? 414 TYR   A CG  1 
ATOM   2966 C CD1 . TYR   A 1 414 ? 82.872  106.579 87.069  1.00 43.89  ? 414 TYR   A CD1 1 
ATOM   2967 C CD2 . TYR   A 1 414 ? 81.459  106.169 85.200  1.00 43.89  ? 414 TYR   A CD2 1 
ATOM   2968 C CE1 . TYR   A 1 414 ? 83.330  107.734 86.472  1.00 43.89  ? 414 TYR   A CE1 1 
ATOM   2969 C CE2 . TYR   A 1 414 ? 81.910  107.317 84.597  1.00 43.89  ? 414 TYR   A CE2 1 
ATOM   2970 C CZ  . TYR   A 1 414 ? 82.843  108.097 85.235  1.00 43.89  ? 414 TYR   A CZ  1 
ATOM   2971 O OH  . TYR   A 1 414 ? 83.289  109.243 84.624  1.00 43.89  ? 414 TYR   A OH  1 
ATOM   2972 N N   . ILE   A 1 415 ? 78.705  105.573 88.251  1.00 46.01  ? 415 ILE   A N   1 
ATOM   2973 C CA  . ILE   A 1 415 ? 77.719  106.650 88.276  1.00 46.01  ? 415 ILE   A CA  1 
ATOM   2974 C C   . ILE   A 1 415 ? 77.342  107.009 89.709  1.00 46.01  ? 415 ILE   A C   1 
ATOM   2975 O O   . ILE   A 1 415 ? 77.198  108.189 90.050  1.00 46.01  ? 415 ILE   A O   1 
ATOM   2976 C CB  . ILE   A 1 415 ? 76.485  106.266 87.440  1.00 46.01  ? 415 ILE   A CB  1 
ATOM   2977 C CG1 . ILE   A 1 415 ? 76.892  105.962 85.998  1.00 46.01  ? 415 ILE   A CG1 1 
ATOM   2978 C CG2 . ILE   A 1 415 ? 75.448  107.373 87.467  1.00 46.01  ? 415 ILE   A CG2 1 
ATOM   2979 C CD1 . ILE   A 1 415 ? 77.421  107.157 85.247  1.00 46.01  ? 415 ILE   A CD1 1 
ATOM   2980 N N   . VAL   A 1 416 ? 77.191  106.008 90.575  1.00 49.07  ? 416 VAL   A N   1 
ATOM   2981 C CA  . VAL   A 1 416 ? 76.631  106.234 91.903  1.00 49.07  ? 416 VAL   A CA  1 
ATOM   2982 C C   . VAL   A 1 416 ? 77.706  106.218 92.982  1.00 49.07  ? 416 VAL   A C   1 
ATOM   2983 O O   . VAL   A 1 416 ? 77.883  107.202 93.706  1.00 49.07  ? 416 VAL   A O   1 
ATOM   2984 C CB  . VAL   A 1 416 ? 75.546  105.192 92.223  1.00 49.07  ? 416 VAL   A CB  1 
ATOM   2985 C CG1 . VAL   A 1 416 ? 75.149  105.272 93.687  1.00 49.07  ? 416 VAL   A CG1 1 
ATOM   2986 C CG2 . VAL   A 1 416 ? 74.347  105.383 91.320  1.00 49.07  ? 416 VAL   A CG2 1 
ATOM   2987 N N   . ILE   A 1 417 ? 78.424  105.098 93.101  1.00 49.30  ? 417 ILE   A N   1 
ATOM   2988 C CA  . ILE   A 1 417 ? 79.248  104.860 94.284  1.00 49.30  ? 417 ILE   A CA  1 
ATOM   2989 C C   . ILE   A 1 417 ? 80.462  105.783 94.306  1.00 49.30  ? 417 ILE   A C   1 
ATOM   2990 O O   . ILE   A 1 417 ? 80.845  106.291 95.365  1.00 49.30  ? 417 ILE   A O   1 
ATOM   2991 C CB  . ILE   A 1 417 ? 79.661  103.379 94.355  1.00 49.30  ? 417 ILE   A CB  1 
ATOM   2992 C CG1 . ILE   A 1 417 ? 78.440  102.476 94.190  1.00 49.30  ? 417 ILE   A CG1 1 
ATOM   2993 C CG2 . ILE   A 1 417 ? 80.342  103.080 95.679  1.00 49.30  ? 417 ILE   A CG2 1 
ATOM   2994 C CD1 . ILE   A 1 417 ? 77.519  102.478 95.378  1.00 49.30  ? 417 ILE   A CD1 1 
ATOM   2995 N N   . PHE   A 1 418 ? 81.094  105.998 93.152  1.00 47.25  ? 418 PHE   A N   1 
ATOM   2996 C CA  . PHE   A 1 418 ? 82.339  106.766 93.114  1.00 47.25  ? 418 PHE   A CA  1 
ATOM   2997 C C   . PHE   A 1 418 ? 82.181  108.232 93.520  1.00 47.25  ? 418 PHE   A C   1 
ATOM   2998 O O   . PHE   A 1 418 ? 83.035  108.723 94.280  1.00 47.25  ? 418 PHE   A O   1 
ATOM   2999 C CB  . PHE   A 1 418 ? 82.984  106.618 91.731  1.00 47.25  ? 418 PHE   A CB  1 
ATOM   3000 C CG  . PHE   A 1 418 ? 84.279  107.361 91.583  1.00 47.25  ? 418 PHE   A CG  1 
ATOM   3001 C CD1 . PHE   A 1 418 ? 85.454  106.830 92.083  1.00 47.25  ? 418 PHE   A CD1 1 
ATOM   3002 C CD2 . PHE   A 1 418 ? 84.326  108.577 90.925  1.00 47.25  ? 418 PHE   A CD2 1 
ATOM   3003 C CE1 . PHE   A 1 418 ? 86.648  107.504 91.945  1.00 47.25  ? 418 PHE   A CE1 1 
ATOM   3004 C CE2 . PHE   A 1 418 ? 85.518  109.255 90.782  1.00 47.25  ? 418 PHE   A CE2 1 
ATOM   3005 C CZ  . PHE   A 1 418 ? 86.679  108.719 91.294  1.00 47.25  ? 418 PHE   A CZ  1 
ATOM   3006 N N   . PRO   A 1 419 ? 81.177  108.995 93.046  1.00 49.24  ? 419 PRO   A N   1 
ATOM   3007 C CA  . PRO   A 1 419 ? 81.020  110.363 93.577  1.00 49.24  ? 419 PRO   A CA  1 
ATOM   3008 C C   . PRO   A 1 419 ? 80.758  110.411 95.072  1.00 49.24  ? 419 PRO   A C   1 
ATOM   3009 O O   . PRO   A 1 419 ? 81.266  111.306 95.759  1.00 49.24  ? 419 PRO   A O   1 
ATOM   3010 C CB  . PRO   A 1 419 ? 79.829  110.908 92.781  1.00 49.24  ? 419 PRO   A CB  1 
ATOM   3011 C CG  . PRO   A 1 419 ? 79.859  110.161 91.528  1.00 49.24  ? 419 PRO   A CG  1 
ATOM   3012 C CD  . PRO   A 1 419 ? 80.253  108.775 91.916  1.00 49.24  ? 419 PRO   A CD  1 
ATOM   3013 N N   . GLN   A 1 420 ? 79.988  109.456 95.600  1.00 56.92  ? 420 GLN   A N   1 
ATOM   3014 C CA  . GLN   A 1 420 ? 79.735  109.417 97.036  1.00 56.92  ? 420 GLN   A CA  1 
ATOM   3015 C C   . GLN   A 1 420 ? 81.008  109.100 97.809  1.00 56.92  ? 420 GLN   A C   1 
ATOM   3016 O O   . GLN   A 1 420 ? 81.237  109.652 98.890  1.00 56.92  ? 420 GLN   A O   1 
ATOM   3017 C CB  . GLN   A 1 420 ? 78.649  108.391 97.348  1.00 56.92  ? 420 GLN   A CB  1 
ATOM   3018 C CG  . GLN   A 1 420 ? 77.365  108.559 96.549  1.00 56.92  ? 420 GLN   A CG  1 
ATOM   3019 C CD  . GLN   A 1 420 ? 76.555  109.774 96.949  1.00 56.92  ? 420 GLN   A CD  1 
ATOM   3020 O OE1 . GLN   A 1 420 ? 76.917  110.911 96.649  1.00 56.92  ? 420 GLN   A OE1 1 
ATOM   3021 N NE2 . GLN   A 1 420 ? 75.440  109.535 97.624  1.00 56.92  ? 420 GLN   A NE2 1 
ATOM   3022 N N   . LEU   A 1 421 ? 81.840  108.204 97.271  1.00 52.38  ? 421 LEU   A N   1 
ATOM   3023 C CA  . LEU   A 1 421 ? 83.121  107.895 97.898  1.00 52.38  ? 421 LEU   A CA  1 
ATOM   3024 C C   . LEU   A 1 421 ? 84.034  109.114 97.908  1.00 52.38  ? 421 LEU   A C   1 
ATOM   3025 O O   . LEU   A 1 421 ? 84.681  109.408 98.923  1.00 52.38  ? 421 LEU   A O   1 
ATOM   3026 C CB  . LEU   A 1 421 ? 83.787  106.730 97.167  1.00 52.38  ? 421 LEU   A CB  1 
ATOM   3027 C CG  . LEU   A 1 421 ? 85.094  106.191 97.744  1.00 52.38  ? 421 LEU   A CG  1 
ATOM   3028 C CD1 . LEU   A 1 421 ? 84.873  105.646 99.144  1.00 52.38  ? 421 LEU   A CD1 1 
ATOM   3029 C CD2 . LEU   A 1 421 ? 85.671  105.124 96.834  1.00 52.38  ? 421 LEU   A CD2 1 
ATOM   3030 N N   . LEU   A 1 422 ? 84.083  109.843 96.789  1.00 51.20  ? 422 LEU   A N   1 
ATOM   3031 C CA  . LEU   A 1 422 ? 84.864  111.075 96.736  1.00 51.20  ? 422 LEU   A CA  1 
ATOM   3032 C C   . LEU   A 1 422 ? 84.357  112.088 97.751  1.00 51.20  ? 422 LEU   A C   1 
ATOM   3033 O O   . LEU   A 1 422 ? 85.151  112.760 98.420  1.00 51.20  ? 422 LEU   A O   1 
ATOM   3034 C CB  . LEU   A 1 422 ? 84.813  111.675 95.332  1.00 51.20  ? 422 LEU   A CB  1 
ATOM   3035 C CG  . LEU   A 1 422 ? 85.687  111.087 94.228  1.00 51.20  ? 422 LEU   A CG  1 
ATOM   3036 C CD1 . LEU   A 1 422 ? 85.663  112.010 93.026  1.00 51.20  ? 422 LEU   A CD1 1 
ATOM   3037 C CD2 . LEU   A 1 422 ? 87.105  110.870 94.711  1.00 51.20  ? 422 LEU   A CD2 1 
ATOM   3038 N N   . CYS   A 1 423 ? 83.035  112.203 97.887  1.00 60.15  ? 423 CYS   A N   1 
ATOM   3039 C CA  . CYS   A 1 423 ? 82.469  113.169 98.821  1.00 60.15  ? 423 CYS   A CA  1 
ATOM   3040 C C   . CYS   A 1 423 ? 82.755  112.792 100.271 1.00 60.15  ? 423 CYS   A C   1 
ATOM   3041 O O   . CYS   A 1 423 ? 83.075  113.662 101.086 1.00 60.15  ? 423 CYS   A O   1 
ATOM   3042 C CB  . CYS   A 1 423 ? 80.966  113.306 98.586  1.00 60.15  ? 423 CYS   A CB  1 
ATOM   3043 S SG  . CYS   A 1 423 ? 80.539  114.367 97.191  1.00 60.15  ? 423 CYS   A SG  1 
ATOM   3044 N N   . VAL   A 1 424 ? 82.641  111.508 100.621 1.00 58.70  ? 424 VAL   A N   1 
ATOM   3045 C CA  . VAL   A 1 424 ? 82.868  111.137 102.016 1.00 58.70  ? 424 VAL   A CA  1 
ATOM   3046 C C   . VAL   A 1 424 ? 84.350  111.183 102.365 1.00 58.70  ? 424 VAL   A C   1 
ATOM   3047 O O   . VAL   A 1 424 ? 84.709  111.459 103.516 1.00 58.70  ? 424 VAL   A O   1 
ATOM   3048 C CB  . VAL   A 1 424 ? 82.257  109.760 102.349 1.00 58.70  ? 424 VAL   A CB  1 
ATOM   3049 C CG1 . VAL   A 1 424 ? 80.749  109.801 102.207 1.00 58.70  ? 424 VAL   A CG1 1 
ATOM   3050 C CG2 . VAL   A 1 424 ? 82.859  108.656 101.501 1.00 58.70  ? 424 VAL   A CG2 1 
ATOM   3051 N N   . LEU   A 1 425 ? 85.240  110.922 101.402 1.00 57.82  ? 425 LEU   A N   1 
ATOM   3052 C CA  . LEU   A 1 425 ? 86.657  110.879 101.746 1.00 57.82  ? 425 LEU   A CA  1 
ATOM   3053 C C   . LEU   A 1 425 ? 87.310  112.254 101.679 1.00 57.82  ? 425 LEU   A C   1 
ATOM   3054 O O   . LEU   A 1 425 ? 88.076  112.624 102.575 1.00 57.82  ? 425 LEU   A O   1 
ATOM   3055 C CB  . LEU   A 1 425 ? 87.390  109.891 100.838 1.00 57.82  ? 425 LEU   A CB  1 
ATOM   3056 C CG  . LEU   A 1 425 ? 87.027  108.425 101.064 1.00 57.82  ? 425 LEU   A CG  1 
ATOM   3057 C CD1 . LEU   A 1 425 ? 88.007  107.517 100.354 1.00 57.82  ? 425 LEU   A CD1 1 
ATOM   3058 C CD2 . LEU   A 1 425 ? 86.985  108.115 102.548 1.00 57.82  ? 425 LEU   A CD2 1 
ATOM   3059 N N   . PHE   A 1 426 ? 87.029  113.029 100.628 1.00 57.77  ? 426 PHE   A N   1 
ATOM   3060 C CA  . PHE   A 1 426 ? 87.787  114.244 100.371 1.00 57.77  ? 426 PHE   A CA  1 
ATOM   3061 C C   . PHE   A 1 426 ? 87.002  115.533 100.557 1.00 57.77  ? 426 PHE   A C   1 
ATOM   3062 O O   . PHE   A 1 426 ? 87.621  116.591 100.704 1.00 57.77  ? 426 PHE   A O   1 
ATOM   3063 C CB  . PHE   A 1 426 ? 88.360  114.210 98.947  1.00 57.77  ? 426 PHE   A CB  1 
ATOM   3064 C CG  . PHE   A 1 426 ? 89.178  112.986 98.661  1.00 57.77  ? 426 PHE   A CG  1 
ATOM   3065 C CD1 . PHE   A 1 426 ? 90.272  112.671 99.448  1.00 57.77  ? 426 PHE   A CD1 1 
ATOM   3066 C CD2 . PHE   A 1 426 ? 88.849  112.144 97.615  1.00 57.77  ? 426 PHE   A CD2 1 
ATOM   3067 C CE1 . PHE   A 1 426 ? 91.025  111.544 99.191  1.00 57.77  ? 426 PHE   A CE1 1 
ATOM   3068 C CE2 . PHE   A 1 426 ? 89.599  111.014 97.354  1.00 57.77  ? 426 PHE   A CE2 1 
ATOM   3069 C CZ  . PHE   A 1 426 ? 90.687  110.714 98.143  1.00 57.77  ? 426 PHE   A CZ  1 
ATOM   3070 N N   . VAL   A 1 427 ? 85.674  115.483 100.556 1.00 64.91  ? 427 VAL   A N   1 
ATOM   3071 C CA  . VAL   A 1 427 ? 84.847  116.678 100.670 1.00 64.91  ? 427 VAL   A CA  1 
ATOM   3072 C C   . VAL   A 1 427 ? 84.351  116.791 102.105 1.00 64.91  ? 427 VAL   A C   1 
ATOM   3073 O O   . VAL   A 1 427 ? 83.628  115.915 102.593 1.00 64.91  ? 427 VAL   A O   1 
ATOM   3074 C CB  . VAL   A 1 427 ? 83.673  116.643 99.680  1.00 64.91  ? 427 VAL   A CB  1 
ATOM   3075 C CG1 . VAL   A 1 427 ? 82.745  117.821 99.918  1.00 64.91  ? 427 VAL   A CG1 1 
ATOM   3076 C CG2 . VAL   A 1 427 ? 84.187  116.643 98.251  1.00 64.91  ? 427 VAL   A CG2 1 
ATOM   3077 N N   . LYS   A 1 428 ? 84.734  117.866 102.784 1.00 79.92  ? 428 LYS   A N   1 
ATOM   3078 C CA  . LYS   A 1 428 ? 84.264  118.102 104.141 1.00 79.92  ? 428 LYS   A CA  1 
ATOM   3079 C C   . LYS   A 1 428 ? 82.889  118.756 104.115 1.00 79.92  ? 428 LYS   A C   1 
ATOM   3080 O O   . LYS   A 1 428 ? 82.624  119.646 103.302 1.00 79.92  ? 428 LYS   A O   1 
ATOM   3081 C CB  . LYS   A 1 428 ? 85.253  118.982 104.907 1.00 79.92  ? 428 LYS   A CB  1 
ATOM   3082 C CG  . LYS   A 1 428 ? 84.939  119.121 106.389 1.00 79.92  ? 428 LYS   A CG  1 
ATOM   3083 C CD  . LYS   A 1 428 ? 86.015  119.906 107.122 1.00 79.92  ? 428 LYS   A CD  1 
ATOM   3084 C CE  . LYS   A 1 428 ? 85.959  121.384 106.772 1.00 79.92  ? 428 LYS   A CE  1 
ATOM   3085 N NZ  . LYS   A 1 428 ? 86.935  122.177 107.570 1.00 79.92  ? 428 LYS   A NZ  1 
ATOM   3086 N N   . GLY   A 1 429 ? 82.014  118.310 105.011 1.00 83.55  ? 429 GLY   A N   1 
ATOM   3087 C CA  . GLY   A 1 429 ? 80.695  118.895 105.134 1.00 83.55  ? 429 GLY   A CA  1 
ATOM   3088 C C   . GLY   A 1 429 ? 79.622  118.301 104.252 1.00 83.55  ? 429 GLY   A C   1 
ATOM   3089 O O   . GLY   A 1 429 ? 78.592  118.951 104.041 1.00 83.55  ? 429 GLY   A O   1 
ATOM   3090 N N   . THR   A 1 430 ? 79.824  117.097 103.726 1.00 77.07  ? 430 THR   A N   1 
ATOM   3091 C CA  . THR   A 1 430 ? 78.785  116.445 102.941 1.00 77.07  ? 430 THR   A CA  1 
ATOM   3092 C C   . THR   A 1 430 ? 77.639  115.998 103.845 1.00 77.07  ? 430 THR   A C   1 
ATOM   3093 O O   . THR   A 1 430 ? 77.808  115.795 105.051 1.00 77.07  ? 430 THR   A O   1 
ATOM   3094 C CB  . THR   A 1 430 ? 79.361  115.256 102.168 1.00 77.07  ? 430 THR   A CB  1 
ATOM   3095 O OG1 . THR   A 1 430 ? 78.388  114.769 101.237 1.00 77.07  ? 430 THR   A OG1 1 
ATOM   3096 C CG2 . THR   A 1 430 ? 79.765  114.134 103.109 1.00 77.07  ? 430 THR   A CG2 1 
ATOM   3097 N N   . ASN   A 1 431 ? 76.452  115.871 103.255 1.00 81.66  ? 431 ASN   A N   1 
ATOM   3098 C CA  . ASN   A 1 431 ? 75.239  115.575 104.002 1.00 81.66  ? 431 ASN   A CA  1 
ATOM   3099 C C   . ASN   A 1 431 ? 74.443  114.484 103.299 1.00 81.66  ? 431 ASN   A C   1 
ATOM   3100 O O   . ASN   A 1 431 ? 74.764  114.063 102.185 1.00 81.66  ? 431 ASN   A O   1 
ATOM   3101 C CB  . ASN   A 1 431 ? 74.364  116.825 104.170 1.00 81.66  ? 431 ASN   A CB  1 
ATOM   3102 C CG  . ASN   A 1 431 ? 75.038  117.904 104.986 1.00 81.66  ? 431 ASN   A CG  1 
ATOM   3103 O OD1 . ASN   A 1 431 ? 75.341  118.982 104.476 1.00 81.66  ? 431 ASN   A OD1 1 
ATOM   3104 N ND2 . ASN   A 1 431 ? 75.273  117.624 106.262 1.00 81.66  ? 431 ASN   A ND2 1 
ATOM   3105 N N   . THR   A 1 432 ? 73.386  114.030 103.977 1.00 81.37  ? 432 THR   A N   1 
ATOM   3106 C CA  . THR   A 1 432 ? 72.464  113.078 103.369 1.00 81.37  ? 432 THR   A CA  1 
ATOM   3107 C C   . THR   A 1 432 ? 71.637  113.733 102.267 1.00 81.37  ? 432 THR   A C   1 
ATOM   3108 O O   . THR   A 1 432 ? 71.232  113.058 101.314 1.00 81.37  ? 432 THR   A O   1 
ATOM   3109 C CB  . THR   A 1 432 ? 71.554  112.476 104.442 1.00 81.37  ? 432 THR   A CB  1 
ATOM   3110 O OG1 . THR   A 1 432 ? 72.342  112.095 105.575 1.00 81.37  ? 432 THR   A OG1 1 
ATOM   3111 C CG2 . THR   A 1 432 ? 70.836  111.243 103.915 1.00 81.37  ? 432 THR   A CG2 1 
ATOM   3112 N N   . TYR   A 1 433 ? 71.380  115.039 102.382 1.00 84.31  ? 433 TYR   A N   1 
ATOM   3113 C CA  . TYR   A 1 433 ? 70.674  115.766 101.330 1.00 84.31  ? 433 TYR   A CA  1 
ATOM   3114 C C   . TYR   A 1 433 ? 71.449  115.733 100.021 1.00 84.31  ? 433 TYR   A C   1 
ATOM   3115 O O   . TYR   A 1 433 ? 70.891  115.420 98.962  1.00 84.31  ? 433 TYR   A O   1 
ATOM   3116 C CB  . TYR   A 1 433 ? 70.440  117.209 101.767 1.00 84.31  ? 433 TYR   A CB  1 
ATOM   3117 C CG  . TYR   A 1 433 ? 69.582  117.337 102.993 1.00 84.31  ? 433 TYR   A CG  1 
ATOM   3118 C CD1 . TYR   A 1 433 ? 68.406  116.616 103.113 1.00 84.31  ? 433 TYR   A CD1 1 
ATOM   3119 C CD2 . TYR   A 1 433 ? 69.961  118.154 104.045 1.00 84.31  ? 433 TYR   A CD2 1 
ATOM   3120 C CE1 . TYR   A 1 433 ? 67.620  116.728 104.231 1.00 84.31  ? 433 TYR   A CE1 1 
ATOM   3121 C CE2 . TYR   A 1 433 ? 69.183  118.270 105.169 1.00 84.31  ? 433 TYR   A CE2 1 
ATOM   3122 C CZ  . TYR   A 1 433 ? 68.015  117.552 105.255 1.00 84.31  ? 433 TYR   A CZ  1 
ATOM   3123 O OH  . TYR   A 1 433 ? 67.232  117.658 106.371 1.00 84.31  ? 433 TYR   A OH  1 
ATOM   3124 N N   . GLY   A 1 434 ? 72.739  116.066 100.076 1.00 72.92  ? 434 GLY   A N   1 
ATOM   3125 C CA  . GLY   A 1 434 ? 73.568  115.983 98.890  1.00 72.92  ? 434 GLY   A CA  1 
ATOM   3126 C C   . GLY   A 1 434 ? 73.696  114.569 98.367  1.00 72.92  ? 434 GLY   A C   1 
ATOM   3127 O O   . GLY   A 1 434 ? 73.739  114.358 97.155  1.00 72.92  ? 434 GLY   A O   1 
ATOM   3128 N N   . ALA   A 1 435 ? 73.734  113.586 99.269  1.00 70.46  ? 435 ALA   A N   1 
ATOM   3129 C CA  . ALA   A 1 435 ? 73.800  112.189 98.852  1.00 70.46  ? 435 ALA   A CA  1 
ATOM   3130 C C   . ALA   A 1 435 ? 72.559  111.790 98.064  1.00 70.46  ? 435 ALA   A C   1 
ATOM   3131 O O   . ALA   A 1 435 ? 72.660  111.201 96.982  1.00 70.46  ? 435 ALA   A O   1 
ATOM   3132 C CB  . ALA   A 1 435 ? 73.971  111.291 100.077 1.00 70.46  ? 435 ALA   A CB  1 
ATOM   3133 N N   . VAL   A 1 436 ? 71.377  112.125 98.587  1.00 68.18  ? 436 VAL   A N   1 
ATOM   3134 C CA  . VAL   A 1 436 ? 70.124  111.782 97.920  1.00 68.18  ? 436 VAL   A CA  1 
ATOM   3135 C C   . VAL   A 1 436 ? 69.999  112.524 96.594  1.00 68.18  ? 436 VAL   A C   1 
ATOM   3136 O O   . VAL   A 1 436 ? 69.597  111.942 95.577  1.00 68.18  ? 436 VAL   A O   1 
ATOM   3137 C CB  . VAL   A 1 436 ? 68.935  112.075 98.856  1.00 68.18  ? 436 VAL   A CB  1 
ATOM   3138 C CG1 . VAL   A 1 436 ? 67.622  112.081 98.090  1.00 68.18  ? 436 VAL   A CG1 1 
ATOM   3139 C CG2 . VAL   A 1 436 ? 68.890  111.061 99.986  1.00 68.18  ? 436 VAL   A CG2 1 
ATOM   3140 N N   . ALA   A 1 437 ? 70.347  113.815 96.579  1.00 66.00  ? 437 ALA   A N   1 
ATOM   3141 C CA  . ALA   A 1 437 ? 70.245  114.598 95.352  1.00 66.00  ? 437 ALA   A CA  1 
ATOM   3142 C C   . ALA   A 1 437 ? 71.202  114.088 94.281  1.00 66.00  ? 437 ALA   A C   1 
ATOM   3143 O O   . ALA   A 1 437 ? 70.825  113.976 93.109  1.00 66.00  ? 437 ALA   A O   1 
ATOM   3144 C CB  . ALA   A 1 437 ? 70.506  116.072 95.650  1.00 66.00  ? 437 ALA   A CB  1 
ATOM   3145 N N   . GLY   A 1 438 ? 72.440  113.768 94.663  1.00 62.70  ? 438 GLY   A N   1 
ATOM   3146 C CA  . GLY   A 1 438 ? 73.381  113.213 93.706  1.00 62.70  ? 438 GLY   A CA  1 
ATOM   3147 C C   . GLY   A 1 438 ? 72.969  111.841 93.216  1.00 62.70  ? 438 GLY   A C   1 
ATOM   3148 O O   . GLY   A 1 438 ? 73.163  111.512 92.045  1.00 62.70  ? 438 GLY   A O   1 
ATOM   3149 N N   . TYR   A 1 439 ? 72.386  111.027 94.101  1.00 61.83  ? 439 TYR   A N   1 
ATOM   3150 C CA  . TYR   A 1 439 ? 71.856  109.728 93.699  1.00 61.83  ? 439 TYR   A CA  1 
ATOM   3151 C C   . TYR   A 1 439 ? 70.771  109.886 92.640  1.00 61.83  ? 439 TYR   A C   1 
ATOM   3152 O O   . TYR   A 1 439 ? 70.822  109.250 91.579  1.00 61.83  ? 439 TYR   A O   1 
ATOM   3153 C CB  . TYR   A 1 439 ? 71.310  109.005 94.931  1.00 61.83  ? 439 TYR   A CB  1 
ATOM   3154 C CG  . TYR   A 1 439 ? 71.048  107.529 94.750  1.00 61.83  ? 439 TYR   A CG  1 
ATOM   3155 C CD1 . TYR   A 1 439 ? 72.040  106.595 95.005  1.00 61.83  ? 439 TYR   A CD1 1 
ATOM   3156 C CD2 . TYR   A 1 439 ? 69.806  107.068 94.341  1.00 61.83  ? 439 TYR   A CD2 1 
ATOM   3157 C CE1 . TYR   A 1 439 ? 71.806  105.245 94.850  1.00 61.83  ? 439 TYR   A CE1 1 
ATOM   3158 C CE2 . TYR   A 1 439 ? 69.564  105.718 94.180  1.00 61.83  ? 439 TYR   A CE2 1 
ATOM   3159 C CZ  . TYR   A 1 439 ? 70.569  104.812 94.436  1.00 61.83  ? 439 TYR   A CZ  1 
ATOM   3160 O OH  . TYR   A 1 439 ? 70.338  103.466 94.279  1.00 61.83  ? 439 TYR   A OH  1 
ATOM   3161 N N   . VAL   A 1 440 ? 69.793  110.754 92.908  1.00 59.36  ? 440 VAL   A N   1 
ATOM   3162 C CA  . VAL   A 1 440 ? 68.684  110.951 91.979  1.00 59.36  ? 440 VAL   A CA  1 
ATOM   3163 C C   . VAL   A 1 440 ? 69.181  111.531 90.659  1.00 59.36  ? 440 VAL   A C   1 
ATOM   3164 O O   . VAL   A 1 440 ? 68.762  111.092 89.582  1.00 59.36  ? 440 VAL   A O   1 
ATOM   3165 C CB  . VAL   A 1 440 ? 67.603  111.835 92.627  1.00 59.36  ? 440 VAL   A CB  1 
ATOM   3166 C CG1 . VAL   A 1 440 ? 66.539  112.219 91.614  1.00 59.36  ? 440 VAL   A CG1 1 
ATOM   3167 C CG2 . VAL   A 1 440 ? 66.970  111.113 93.804  1.00 59.36  ? 440 VAL   A CG2 1 
ATOM   3168 N N   . SER   A 1 441 ? 70.094  112.506 90.718  1.00 56.73  ? 441 SER   A N   1 
ATOM   3169 C CA  . SER   A 1 441 ? 70.629  113.107 89.499  1.00 56.73  ? 441 SER   A CA  1 
ATOM   3170 C C   . SER   A 1 441 ? 71.426  112.102 88.674  1.00 56.73  ? 441 SER   A C   1 
ATOM   3171 O O   . SER   A 1 441 ? 71.307  112.072 87.442  1.00 56.73  ? 441 SER   A O   1 
ATOM   3172 C CB  . SER   A 1 441 ? 71.495  114.314 89.852  1.00 56.73  ? 441 SER   A CB  1 
ATOM   3173 O OG  . SER   A 1 441 ? 72.121  114.842 88.698  1.00 56.73  ? 441 SER   A OG  1 
ATOM   3174 N N   . GLY   A 1 442 ? 72.246  111.278 89.332  1.00 55.59  ? 442 GLY   A N   1 
ATOM   3175 C CA  . GLY   A 1 442 ? 73.006  110.272 88.611  1.00 55.59  ? 442 GLY   A CA  1 
ATOM   3176 C C   . GLY   A 1 442 ? 72.122  109.237 87.946  1.00 55.59  ? 442 GLY   A C   1 
ATOM   3177 O O   . GLY   A 1 442 ? 72.328  108.898 86.778  1.00 55.59  ? 442 GLY   A O   1 
ATOM   3178 N N   . LEU   A 1 443 ? 71.108  108.742 88.667  1.00 58.84  ? 443 LEU   A N   1 
ATOM   3179 C CA  . LEU   A 1 443 ? 70.175  107.801 88.048  1.00 58.84  ? 443 LEU   A CA  1 
ATOM   3180 C C   . LEU   A 1 443 ? 69.391  108.444 86.910  1.00 58.84  ? 443 LEU   A C   1 
ATOM   3181 O O   . LEU   A 1 443 ? 69.156  107.800 85.883  1.00 58.84  ? 443 LEU   A O   1 
ATOM   3182 C CB  . LEU   A 1 443 ? 69.217  107.202 89.082  1.00 58.84  ? 443 LEU   A CB  1 
ATOM   3183 C CG  . LEU   A 1 443 ? 69.625  105.994 89.937  1.00 58.84  ? 443 LEU   A CG  1 
ATOM   3184 C CD1 . LEU   A 1 443 ? 69.848  104.791 89.031  1.00 58.84  ? 443 LEU   A CD1 1 
ATOM   3185 C CD2 . LEU   A 1 443 ? 70.842  106.219 90.798  1.00 58.84  ? 443 LEU   A CD2 1 
ATOM   3186 N N   . PHE   A 1 444 ? 68.992  109.710 87.060  1.00 58.33  ? 444 PHE   A N   1 
ATOM   3187 C CA  . PHE   A 1 444 ? 68.215  110.363 86.011  1.00 58.33  ? 444 PHE   A CA  1 
ATOM   3188 C C   . PHE   A 1 444 ? 69.049  110.543 84.748  1.00 58.33  ? 444 PHE   A C   1 
ATOM   3189 O O   . PHE   A 1 444 ? 68.605  110.194 83.647  1.00 58.33  ? 444 PHE   A O   1 
ATOM   3190 C CB  . PHE   A 1 444 ? 67.679  111.705 86.525  1.00 58.33  ? 444 PHE   A CB  1 
ATOM   3191 C CG  . PHE   A 1 444 ? 66.754  112.416 85.566  1.00 58.33  ? 444 PHE   A CG  1 
ATOM   3192 C CD1 . PHE   A 1 444 ? 67.246  113.196 84.527  1.00 58.33  ? 444 PHE   A CD1 1 
ATOM   3193 C CD2 . PHE   A 1 444 ? 65.381  112.298 85.708  1.00 58.33  ? 444 PHE   A CD2 1 
ATOM   3194 C CE1 . PHE   A 1 444 ? 66.389  113.839 83.656  1.00 58.33  ? 444 PHE   A CE1 1 
ATOM   3195 C CE2 . PHE   A 1 444 ? 64.520  112.940 84.840  1.00 58.33  ? 444 PHE   A CE2 1 
ATOM   3196 C CZ  . PHE   A 1 444 ? 65.025  113.711 83.813  1.00 58.33  ? 444 PHE   A CZ  1 
ATOM   3197 N N   . LEU   A 1 445 ? 70.269  111.068 84.885  1.00 56.32  ? 445 LEU   A N   1 
ATOM   3198 C CA  . LEU   A 1 445 ? 71.112  111.262 83.711  1.00 56.32  ? 445 LEU   A CA  1 
ATOM   3199 C C   . LEU   A 1 445 ? 71.626  109.948 83.136  1.00 56.32  ? 445 LEU   A C   1 
ATOM   3200 O O   . LEU   A 1 445 ? 71.976  109.904 81.953  1.00 56.32  ? 445 LEU   A O   1 
ATOM   3201 C CB  . LEU   A 1 445 ? 72.286  112.186 84.038  1.00 56.32  ? 445 LEU   A CB  1 
ATOM   3202 C CG  . LEU   A 1 445 ? 72.060  113.686 83.832  1.00 56.32  ? 445 LEU   A CG  1 
ATOM   3203 C CD1 . LEU   A 1 445 ? 71.196  114.282 84.930  1.00 56.32  ? 445 LEU   A CD1 1 
ATOM   3204 C CD2 . LEU   A 1 445 ? 73.389  114.417 83.738  1.00 56.32  ? 445 LEU   A CD2 1 
ATOM   3205 N N   . ARG   A 1 446 ? 71.690  108.883 83.938  1.00 56.03  ? 446 ARG   A N   1 
ATOM   3206 C CA  . ARG   A 1 446 ? 72.083  107.586 83.402  1.00 56.03  ? 446 ARG   A CA  1 
ATOM   3207 C C   . ARG   A 1 446 ? 70.940  106.924 82.639  1.00 56.03  ? 446 ARG   A C   1 
ATOM   3208 O O   . ARG   A 1 446 ? 71.164  106.324 81.582  1.00 56.03  ? 446 ARG   A O   1 
ATOM   3209 C CB  . ARG   A 1 446 ? 72.566  106.685 84.537  1.00 56.03  ? 446 ARG   A CB  1 
ATOM   3210 C CG  . ARG   A 1 446 ? 73.099  105.340 84.089  1.00 56.03  ? 446 ARG   A CG  1 
ATOM   3211 C CD  . ARG   A 1 446 ? 74.257  105.512 83.125  1.00 56.03  ? 446 ARG   A CD  1 
ATOM   3212 N NE  . ARG   A 1 446 ? 74.627  104.257 82.486  1.00 56.03  ? 446 ARG   A NE  1 
ATOM   3213 C CZ  . ARG   A 1 446 ? 73.976  103.714 81.467  1.00 56.03  ? 446 ARG   A CZ  1 
ATOM   3214 N NH1 . ARG   A 1 446 ? 72.912  104.294 80.938  1.00 56.03  ? 446 ARG   A NH1 1 
ATOM   3215 N NH2 . ARG   A 1 446 ? 74.406  102.561 80.965  1.00 56.03  ? 446 ARG   A NH2 1 
ATOM   3216 N N   . ILE   A 1 447 ? 69.715  107.013 83.162  1.00 61.47  ? 447 ILE   A N   1 
ATOM   3217 C CA  . ILE   A 1 447 ? 68.576  106.359 82.524  1.00 61.47  ? 447 ILE   A CA  1 
ATOM   3218 C C   . ILE   A 1 447 ? 68.146  107.121 81.275  1.00 61.47  ? 447 ILE   A C   1 
ATOM   3219 O O   . ILE   A 1 447 ? 67.902  106.524 80.220  1.00 61.47  ? 447 ILE   A O   1 
ATOM   3220 C CB  . ILE   A 1 447 ? 67.419  106.209 83.529  1.00 61.47  ? 447 ILE   A CB  1 
ATOM   3221 C CG1 . ILE   A 1 447 ? 67.776  105.171 84.594  1.00 61.47  ? 447 ILE   A CG1 1 
ATOM   3222 C CG2 . ILE   A 1 447 ? 66.132  105.816 82.824  1.00 61.47  ? 447 ILE   A CG2 1 
ATOM   3223 C CD1 . ILE   A 1 447 ? 66.862  105.193 85.794  1.00 61.47  ? 447 ILE   A CD1 1 
ATOM   3224 N N   . THR   A 1 448 ? 68.058  108.452 81.369  1.00 65.76  ? 448 THR   A N   1 
ATOM   3225 C CA  . THR   A 1 448 ? 67.639  109.249 80.220  1.00 65.76  ? 448 THR   A CA  1 
ATOM   3226 C C   . THR   A 1 448 ? 68.655  109.223 79.086  1.00 65.76  ? 448 THR   A C   1 
ATOM   3227 O O   . THR   A 1 448 ? 68.309  109.575 77.954  1.00 65.76  ? 448 THR   A O   1 
ATOM   3228 C CB  . THR   A 1 448 ? 67.372  110.695 80.639  1.00 65.76  ? 448 THR   A CB  1 
ATOM   3229 O OG1 . THR   A 1 448 ? 68.529  111.229 81.294  1.00 65.76  ? 448 THR   A OG1 1 
ATOM   3230 C CG2 . THR   A 1 448 ? 66.173  110.769 81.571  1.00 65.76  ? 448 THR   A CG2 1 
ATOM   3231 N N   . GLY   A 1 449 ? 69.898  108.823 79.360  1.00 66.28  ? 449 GLY   A N   1 
ATOM   3232 C CA  . GLY   A 1 449 ? 70.850  108.590 78.291  1.00 66.28  ? 449 GLY   A CA  1 
ATOM   3233 C C   . GLY   A 1 449 ? 70.573  107.333 77.496  1.00 66.28  ? 449 GLY   A C   1 
ATOM   3234 O O   . GLY   A 1 449 ? 71.088  107.188 76.384  1.00 66.28  ? 449 GLY   A O   1 
ATOM   3235 N N   . GLY   A 1 450 ? 69.782  106.417 78.046  1.00 72.80  ? 450 GLY   A N   1 
ATOM   3236 C CA  . GLY   A 1 450 ? 69.383  105.227 77.325  1.00 72.80  ? 450 GLY   A CA  1 
ATOM   3237 C C   . GLY   A 1 450 ? 70.367  104.083 77.430  1.00 72.80  ? 450 GLY   A C   1 
ATOM   3238 O O   . GLY   A 1 450 ? 71.583  104.294 77.409  1.00 72.80  ? 450 GLY   A O   1 
ATOM   3239 N N   . GLU   A 1 451 ? 69.850  102.867 77.545  1.00 81.25  ? 451 GLU   A N   1 
ATOM   3240 C CA  . GLU   A 1 451 ? 70.674  101.659 77.569  1.00 81.25  ? 451 GLU   A CA  1 
ATOM   3241 C C   . GLU   A 1 451 ? 70.349  100.810 76.350  1.00 81.25  ? 451 GLU   A C   1 
ATOM   3242 O O   . GLU   A 1 451 ? 69.206  100.331 76.222  1.00 81.25  ? 451 GLU   A O   1 
ATOM   3243 C CB  . GLU   A 1 451 ? 70.442  100.865 78.854  1.00 81.25  ? 451 GLU   A CB  1 
ATOM   3244 C CG  . GLU   A 1 451 ? 71.347  99.648  79.013  1.00 81.25  ? 451 GLU   A CG  1 
ATOM   3245 C CD  . GLU   A 1 451 ? 72.824  100.000 79.026  1.00 81.25  ? 451 GLU   A CD  1 
ATOM   3246 O OE1 . GLU   A 1 451 ? 73.182  101.077 79.545  1.00 81.25  ? 451 GLU   A OE1 1 
ATOM   3247 O OE2 . GLU   A 1 451 ? 73.630  99.196  78.514  1.00 81.25  ? 451 GLU   A OE2 1 
ATOM   3248 N N   . PRO   A 1 452 ? 71.292  100.619 75.424  1.00 85.30  ? 452 PRO   A N   1 
ATOM   3249 C CA  . PRO   A 1 452 ? 71.014  99.769  74.253  1.00 85.30  ? 452 PRO   A CA  1 
ATOM   3250 C C   . PRO   A 1 452 ? 70.711  98.322  74.602  1.00 85.30  ? 452 PRO   A C   1 
ATOM   3251 O O   . PRO   A 1 452 ? 69.961  97.661  73.872  1.00 85.30  ? 452 PRO   A O   1 
ATOM   3252 C CB  . PRO   A 1 452 ? 72.303  99.889  73.427  1.00 85.30  ? 452 PRO   A CB  1 
ATOM   3253 C CG  . PRO   A 1 452 ? 72.905  101.186 73.860  1.00 85.30  ? 452 PRO   A CG  1 
ATOM   3254 C CD  . PRO   A 1 452 ? 72.603  101.279 75.324  1.00 85.30  ? 452 PRO   A CD  1 
ATOM   3255 N N   . TYR   A 1 453 ? 71.282  97.807  75.693  1.00 75.82  ? 453 TYR   A N   1 
ATOM   3256 C CA  . TYR   A 1 453 ? 71.084  96.405  76.052  1.00 75.82  ? 453 TYR   A CA  1 
ATOM   3257 C C   . TYR   A 1 453 ? 69.655  96.141  76.510  1.00 75.82  ? 453 TYR   A C   1 
ATOM   3258 O O   . TYR   A 1 453 ? 69.081  95.092  76.196  1.00 75.82  ? 453 TYR   A O   1 
ATOM   3259 C CB  . TYR   A 1 453 ? 72.081  96.003  77.138  1.00 75.82  ? 453 TYR   A CB  1 
ATOM   3260 C CG  . TYR   A 1 453 ? 73.515  95.911  76.660  1.00 75.82  ? 453 TYR   A CG  1 
ATOM   3261 C CD1 . TYR   A 1 453 ? 73.823  95.950  75.305  1.00 75.82  ? 453 TYR   A CD1 1 
ATOM   3262 C CD2 . TYR   A 1 453 ? 74.561  95.799  77.566  1.00 75.82  ? 453 TYR   A CD2 1 
ATOM   3263 C CE1 . TYR   A 1 453 ? 75.129  95.870  74.866  1.00 75.82  ? 453 TYR   A CE1 1 
ATOM   3264 C CE2 . TYR   A 1 453 ? 75.872  95.717  77.136  1.00 75.82  ? 453 TYR   A CE2 1 
ATOM   3265 C CZ  . TYR   A 1 453 ? 76.149  95.754  75.785  1.00 75.82  ? 453 TYR   A CZ  1 
ATOM   3266 O OH  . TYR   A 1 453 ? 77.451  95.674  75.351  1.00 75.82  ? 453 TYR   A OH  1 
ATOM   3267 N N   . LEU   A 1 454 ? 69.065  97.075  77.249  1.00 80.35  ? 454 LEU   A N   1 
ATOM   3268 C CA  . LEU   A 1 454 ? 67.717  96.920  77.778  1.00 80.35  ? 454 LEU   A CA  1 
ATOM   3269 C C   . LEU   A 1 454 ? 66.650  97.476  76.846  1.00 80.35  ? 454 LEU   A C   1 
ATOM   3270 O O   . LEU   A 1 454 ? 65.482  97.549  77.245  1.00 80.35  ? 454 LEU   A O   1 
ATOM   3271 C CB  . LEU   A 1 454 ? 67.607  97.591  79.148  1.00 80.35  ? 454 LEU   A CB  1 
ATOM   3272 C CG  . LEU   A 1 454 ? 67.678  96.672  80.368  1.00 80.35  ? 454 LEU   A CG  1 
ATOM   3273 C CD1 . LEU   A 1 454 ? 69.069  96.074  80.516  1.00 80.35  ? 454 LEU   A CD1 1 
ATOM   3274 C CD2 . LEU   A 1 454 ? 67.276  97.424  81.626  1.00 80.35  ? 454 LEU   A CD2 1 
ATOM   3275 N N   . TYR   A 1 455 ? 67.030  97.869  75.626  1.00 87.38  ? 455 TYR   A N   1 
ATOM   3276 C CA  . TYR   A 1 455 ? 66.124  98.473  74.643  1.00 87.38  ? 455 TYR   A CA  1 
ATOM   3277 C C   . TYR   A 1 455 ? 65.447  99.722  75.206  1.00 87.38  ? 455 TYR   A C   1 
ATOM   3278 O O   . TYR   A 1 455 ? 64.255  99.954  74.997  1.00 87.38  ? 455 TYR   A O   1 
ATOM   3279 C CB  . TYR   A 1 455 ? 65.083  97.466  74.143  1.00 87.38  ? 455 TYR   A CB  1 
ATOM   3280 C CG  . TYR   A 1 455 ? 65.650  96.345  73.298  1.00 87.38  ? 455 TYR   A CG  1 
ATOM   3281 C CD1 . TYR   A 1 455 ? 66.933  96.422  72.770  1.00 87.38  ? 455 TYR   A CD1 1 
ATOM   3282 C CD2 . TYR   A 1 455 ? 64.900  95.208  73.029  1.00 87.38  ? 455 TYR   A CD2 1 
ATOM   3283 C CE1 . TYR   A 1 455 ? 67.452  95.398  72.000  1.00 87.38  ? 455 TYR   A CE1 1 
ATOM   3284 C CE2 . TYR   A 1 455 ? 65.410  94.180  72.259  1.00 87.38  ? 455 TYR   A CE2 1 
ATOM   3285 C CZ  . TYR   A 1 455 ? 66.686  94.281  71.748  1.00 87.38  ? 455 TYR   A CZ  1 
ATOM   3286 O OH  . TYR   A 1 455 ? 67.196  93.258  70.981  1.00 87.38  ? 455 TYR   A OH  1 
ATOM   3287 N N   . LEU   A 1 456 ? 66.217  100.535 75.925  1.00 83.11  ? 456 LEU   A N   1 
ATOM   3288 C CA  . LEU   A 1 456 ? 65.709  101.739 76.569  1.00 83.11  ? 456 LEU   A CA  1 
ATOM   3289 C C   . LEU   A 1 456 ? 65.989  102.944 75.679  1.00 83.11  ? 456 LEU   A C   1 
ATOM   3290 O O   . LEU   A 1 456 ? 67.152  103.284 75.434  1.00 83.11  ? 456 LEU   A O   1 
ATOM   3291 C CB  . LEU   A 1 456 ? 66.346  101.927 77.945  1.00 83.11  ? 456 LEU   A CB  1 
ATOM   3292 C CG  . LEU   A 1 456 ? 65.705  102.974 78.858  1.00 83.11  ? 456 LEU   A CG  1 
ATOM   3293 C CD1 . LEU   A 1 456 ? 64.206  102.752 78.963  1.00 83.11  ? 456 LEU   A CD1 1 
ATOM   3294 C CD2 . LEU   A 1 456 ? 66.351  102.949 80.232  1.00 83.11  ? 456 LEU   A CD2 1 
ATOM   3295 N N   . GLN   A 1 457 ? 64.928  103.583 75.205  1.00 83.24  ? 457 GLN   A N   1 
ATOM   3296 C CA  . GLN   A 1 457 ? 65.081  104.751 74.347  1.00 83.24  ? 457 GLN   A CA  1 
ATOM   3297 C C   . GLN   A 1 457 ? 65.585  105.937 75.161  1.00 83.24  ? 457 GLN   A C   1 
ATOM   3298 O O   . GLN   A 1 457 ? 65.056  106.208 76.246  1.00 83.24  ? 457 GLN   A O   1 
ATOM   3299 C CB  . GLN   A 1 457 ? 63.754  105.094 73.676  1.00 83.24  ? 457 GLN   A CB  1 
ATOM   3300 C CG  . GLN   A 1 457 ? 63.541  104.407 72.338  1.00 83.24  ? 457 GLN   A CG  1 
ATOM   3301 C CD  . GLN   A 1 457 ? 64.605  104.769 71.323  1.00 83.24  ? 457 GLN   A CD  1 
ATOM   3302 O OE1 . GLN   A 1 457 ? 65.136  103.903 70.628  1.00 83.24  ? 457 GLN   A OE1 1 
ATOM   3303 N NE2 . GLN   A 1 457 ? 64.924  106.054 71.231  1.00 83.24  ? 457 GLN   A NE2 1 
ATOM   3304 N N   . PRO   A 1 458 ? 66.605  106.655 74.689  1.00 78.26  ? 458 PRO   A N   1 
ATOM   3305 C CA  . PRO   A 1 458 ? 67.103  107.815 75.441  1.00 78.26  ? 458 PRO   A CA  1 
ATOM   3306 C C   . PRO   A 1 458 ? 66.094  108.954 75.433  1.00 78.26  ? 458 PRO   A C   1 
ATOM   3307 O O   . PRO   A 1 458 ? 65.626  109.381 74.375  1.00 78.26  ? 458 PRO   A O   1 
ATOM   3308 C CB  . PRO   A 1 458 ? 68.388  108.199 74.699  1.00 78.26  ? 458 PRO   A CB  1 
ATOM   3309 C CG  . PRO   A 1 458 ? 68.264  107.578 73.352  1.00 78.26  ? 458 PRO   A CG  1 
ATOM   3310 C CD  . PRO   A 1 458 ? 67.448  106.339 73.525  1.00 78.26  ? 458 PRO   A CD  1 
ATOM   3311 N N   . LEU   A 1 459 ? 65.759  109.442 76.629  1.00 77.07  ? 459 LEU   A N   1 
ATOM   3312 C CA  . LEU   A 1 459 ? 64.867  110.592 76.733  1.00 77.07  ? 459 LEU   A CA  1 
ATOM   3313 C C   . LEU   A 1 459 ? 65.568  111.873 76.300  1.00 77.07  ? 459 LEU   A C   1 
ATOM   3314 O O   . LEU   A 1 459 ? 64.995  112.681 75.559  1.00 77.07  ? 459 LEU   A O   1 
ATOM   3315 C CB  . LEU   A 1 459 ? 64.344  110.726 78.163  1.00 77.07  ? 459 LEU   A CB  1 
ATOM   3316 C CG  . LEU   A 1 459 ? 62.943  110.188 78.464  1.00 77.07  ? 459 LEU   A CG  1 
ATOM   3317 C CD1 . LEU   A 1 459 ? 62.778  108.756 77.979  1.00 77.07  ? 459 LEU   A CD1 1 
ATOM   3318 C CD2 . LEU   A 1 459 ? 62.647  110.288 79.952  1.00 77.07  ? 459 LEU   A CD2 1 
ATOM   3319 N N   . ILE   A 1 460 ? 66.805  112.074 76.746  1.00 74.51  ? 460 ILE   A N   1 
ATOM   3320 C CA  . ILE   A 1 460 ? 67.590  113.256 76.407  1.00 74.51  ? 460 ILE   A CA  1 
ATOM   3321 C C   . ILE   A 1 460 ? 68.481  112.918 75.223  1.00 74.51  ? 460 ILE   A C   1 
ATOM   3322 O O   . ILE   A 1 460 ? 69.217  111.924 75.252  1.00 74.51  ? 460 ILE   A O   1 
ATOM   3323 C CB  . ILE   A 1 460 ? 68.425  113.736 77.606  1.00 74.51  ? 460 ILE   A CB  1 
ATOM   3324 C CG1 . ILE   A 1 460 ? 67.525  113.975 78.819  1.00 74.51  ? 460 ILE   A CG1 1 
ATOM   3325 C CG2 . ILE   A 1 460 ? 69.193  114.996 77.248  1.00 74.51  ? 460 ILE   A CG2 1 
ATOM   3326 C CD1 . ILE   A 1 460 ? 68.251  114.543 80.015  1.00 74.51  ? 460 ILE   A CD1 1 
ATOM   3327 N N   . PHE   A 1 461 ? 68.414  113.741 74.180  1.00 80.69  ? 461 PHE   A N   1 
ATOM   3328 C CA  . PHE   A 1 461 ? 69.130  113.488 72.932  1.00 80.69  ? 461 PHE   A CA  1 
ATOM   3329 C C   . PHE   A 1 461 ? 70.347  114.404 72.877  1.00 80.69  ? 461 PHE   A C   1 
ATOM   3330 O O   . PHE   A 1 461 ? 70.277  115.541 72.410  1.00 80.69  ? 461 PHE   A O   1 
ATOM   3331 C CB  . PHE   A 1 461 ? 68.208  113.691 71.738  1.00 80.69  ? 461 PHE   A CB  1 
ATOM   3332 C CG  . PHE   A 1 461 ? 67.330  112.512 71.455  1.00 80.69  ? 461 PHE   A CG  1 
ATOM   3333 C CD1 . PHE   A 1 461 ? 66.040  112.456 71.956  1.00 80.69  ? 461 PHE   A CD1 1 
ATOM   3334 C CD2 . PHE   A 1 461 ? 67.799  111.449 70.704  1.00 80.69  ? 461 PHE   A CD2 1 
ATOM   3335 C CE1 . PHE   A 1 461 ? 65.232  111.366 71.702  1.00 80.69  ? 461 PHE   A CE1 1 
ATOM   3336 C CE2 . PHE   A 1 461 ? 66.997  110.360 70.449  1.00 80.69  ? 461 PHE   A CE2 1 
ATOM   3337 C CZ  . PHE   A 1 461 ? 65.712  110.317 70.947  1.00 80.69  ? 461 PHE   A CZ  1 
ATOM   3338 N N   . TYR   A 1 462 ? 71.473  113.893 73.365  1.00 77.31  ? 462 TYR   A N   1 
ATOM   3339 C CA  . TYR   A 1 462 ? 72.723  114.625 73.296  1.00 77.31  ? 462 TYR   A CA  1 
ATOM   3340 C C   . TYR   A 1 462 ? 73.216  114.677 71.849  1.00 77.31  ? 462 TYR   A C   1 
ATOM   3341 O O   . TYR   A 1 462 ? 72.853  113.824 71.035  1.00 77.31  ? 462 TYR   A O   1 
ATOM   3342 C CB  . TYR   A 1 462 ? 73.769  113.961 74.188  1.00 77.31  ? 462 TYR   A CB  1 
ATOM   3343 C CG  . TYR   A 1 462 ? 73.380  113.895 75.648  1.00 77.31  ? 462 TYR   A CG  1 
ATOM   3344 C CD1 . TYR   A 1 462 ? 73.589  114.977 76.492  1.00 77.31  ? 462 TYR   A CD1 1 
ATOM   3345 C CD2 . TYR   A 1 462 ? 72.811  112.747 76.183  1.00 77.31  ? 462 TYR   A CD2 1 
ATOM   3346 C CE1 . TYR   A 1 462 ? 73.237  114.919 77.825  1.00 77.31  ? 462 TYR   A CE1 1 
ATOM   3347 C CE2 . TYR   A 1 462 ? 72.457  112.680 77.514  1.00 77.31  ? 462 TYR   A CE2 1 
ATOM   3348 C CZ  . TYR   A 1 462 ? 72.672  113.768 78.330  1.00 77.31  ? 462 TYR   A CZ  1 
ATOM   3349 O OH  . TYR   A 1 462 ? 72.320  113.704 79.657  1.00 77.31  ? 462 TYR   A OH  1 
ATOM   3350 N N   . PRO   A 1 463 ? 74.018  115.686 71.496  1.00 80.69  ? 463 PRO   A N   1 
ATOM   3351 C CA  . PRO   A 1 463 ? 74.533  115.768 70.123  1.00 80.69  ? 463 PRO   A CA  1 
ATOM   3352 C C   . PRO   A 1 463 ? 75.426  114.587 69.774  1.00 80.69  ? 463 PRO   A C   1 
ATOM   3353 O O   . PRO   A 1 463 ? 76.139  114.044 70.619  1.00 80.69  ? 463 PRO   A O   1 
ATOM   3354 C CB  . PRO   A 1 463 ? 75.321  117.085 70.112  1.00 80.69  ? 463 PRO   A CB  1 
ATOM   3355 C CG  . PRO   A 1 463 ? 75.532  117.434 71.547  1.00 80.69  ? 463 PRO   A CG  1 
ATOM   3356 C CD  . PRO   A 1 463 ? 74.354  116.889 72.276  1.00 80.69  ? 463 PRO   A CD  1 
ATOM   3357 N N   . GLY   A 1 464 ? 75.377  114.194 68.504  1.00 87.39  ? 464 GLY   A N   1 
ATOM   3358 C CA  . GLY   A 1 464 ? 76.159  113.079 68.015  1.00 87.39  ? 464 GLY   A CA  1 
ATOM   3359 C C   . GLY   A 1 464 ? 75.478  111.731 68.069  1.00 87.39  ? 464 GLY   A C   1 
ATOM   3360 O O   . GLY   A 1 464 ? 76.126  110.721 67.772  1.00 87.39  ? 464 GLY   A O   1 
ATOM   3361 N N   . TYR   A 1 465 ? 74.199  111.680 68.436  1.00 89.62  ? 465 TYR   A N   1 
ATOM   3362 C CA  . TYR   A 1 465 ? 73.491  110.411 68.534  1.00 89.62  ? 465 TYR   A CA  1 
ATOM   3363 C C   . TYR   A 1 465 ? 73.312  109.778 67.158  1.00 89.62  ? 465 TYR   A C   1 
ATOM   3364 O O   . TYR   A 1 465 ? 73.086  110.469 66.161  1.00 89.62  ? 465 TYR   A O   1 
ATOM   3365 C CB  . TYR   A 1 465 ? 72.137  110.616 69.218  1.00 89.62  ? 465 TYR   A CB  1 
ATOM   3366 C CG  . TYR   A 1 465 ? 71.116  111.400 68.415  1.00 89.62  ? 465 TYR   A CG  1 
ATOM   3367 C CD1 . TYR   A 1 465 ? 71.026  112.781 68.538  1.00 89.62  ? 465 TYR   A CD1 1 
ATOM   3368 C CD2 . TYR   A 1 465 ? 70.213  110.759 67.572  1.00 89.62  ? 465 TYR   A CD2 1 
ATOM   3369 C CE1 . TYR   A 1 465 ? 70.093  113.504 67.820  1.00 89.62  ? 465 TYR   A CE1 1 
ATOM   3370 C CE2 . TYR   A 1 465 ? 69.277  111.475 66.850  1.00 89.62  ? 465 TYR   A CE2 1 
ATOM   3371 C CZ  . TYR   A 1 465 ? 69.220  112.846 66.980  1.00 89.62  ? 465 TYR   A CZ  1 
ATOM   3372 O OH  . TYR   A 1 465 ? 68.288  113.563 66.267  1.00 89.62  ? 465 TYR   A OH  1 
ATOM   3373 N N   . TYR   A 1 466 ? 73.422  108.455 67.110  1.00 97.43  ? 466 TYR   A N   1 
ATOM   3374 C CA  . TYR   A 1 466 ? 73.287  107.694 65.878  1.00 97.43  ? 466 TYR   A CA  1 
ATOM   3375 C C   . TYR   A 1 466 ? 72.458  106.447 66.147  1.00 97.43  ? 466 TYR   A C   1 
ATOM   3376 O O   . TYR   A 1 466 ? 72.482  105.913 67.262  1.00 97.43  ? 466 TYR   A O   1 
ATOM   3377 C CB  . TYR   A 1 466 ? 74.659  107.294 65.308  1.00 97.43  ? 466 TYR   A CB  1 
ATOM   3378 C CG  . TYR   A 1 466 ? 75.379  106.225 66.102  1.00 97.43  ? 466 TYR   A CG  1 
ATOM   3379 C CD1 . TYR   A 1 466 ? 76.017  106.530 67.297  1.00 97.43  ? 466 TYR   A CD1 1 
ATOM   3380 C CD2 . TYR   A 1 466 ? 75.429  104.913 65.649  1.00 97.43  ? 466 TYR   A CD2 1 
ATOM   3381 C CE1 . TYR   A 1 466 ? 76.676  105.557 68.023  1.00 97.43  ? 466 TYR   A CE1 1 
ATOM   3382 C CE2 . TYR   A 1 466 ? 76.086  103.933 66.369  1.00 97.43  ? 466 TYR   A CE2 1 
ATOM   3383 C CZ  . TYR   A 1 466 ? 76.708  104.261 67.555  1.00 97.43  ? 466 TYR   A CZ  1 
ATOM   3384 O OH  . TYR   A 1 466 ? 77.364  103.290 68.275  1.00 97.43  ? 466 TYR   A OH  1 
ATOM   3385 N N   . PRO   A 1 467 ? 71.712  105.966 65.151  1.00 102.26 ? 467 PRO   A N   1 
ATOM   3386 C CA  . PRO   A 1 467 ? 70.972  104.710 65.321  1.00 102.26 ? 467 PRO   A CA  1 
ATOM   3387 C C   . PRO   A 1 467 ? 71.787  103.497 64.901  1.00 102.26 ? 467 PRO   A C   1 
ATOM   3388 O O   . PRO   A 1 467 ? 72.489  103.500 63.887  1.00 102.26 ? 467 PRO   A O   1 
ATOM   3389 C CB  . PRO   A 1 467 ? 69.758  104.902 64.403  1.00 102.26 ? 467 PRO   A CB  1 
ATOM   3390 C CG  . PRO   A 1 467 ? 70.231  105.837 63.334  1.00 102.26 ? 467 PRO   A CG  1 
ATOM   3391 C CD  . PRO   A 1 467 ? 71.414  106.614 63.861  1.00 102.26 ? 467 PRO   A CD  1 
ATOM   3392 N N   . ASP   A 1 468 ? 71.691  102.442 65.705  1.00 106.42 ? 468 ASP   A N   1 
ATOM   3393 C CA  . ASP   A 1 468 ? 72.410  101.206 65.439  1.00 106.42 ? 468 ASP   A CA  1 
ATOM   3394 C C   . ASP   A 1 468 ? 71.568  100.293 64.546  1.00 106.42 ? 468 ASP   A C   1 
ATOM   3395 O O   . ASP   A 1 468 ? 70.558  100.705 63.970  1.00 106.42 ? 468 ASP   A O   1 
ATOM   3396 C CB  . ASP   A 1 468 ? 72.814  100.535 66.754  1.00 106.42 ? 468 ASP   A CB  1 
ATOM   3397 C CG  . ASP   A 1 468 ? 71.623  100.071 67.583  1.00 106.42 ? 468 ASP   A CG  1 
ATOM   3398 O OD1 . ASP   A 1 468 ? 70.468  100.424 67.261  1.00 106.42 ? 468 ASP   A OD1 1 
ATOM   3399 O OD2 . ASP   A 1 468 ? 71.848  99.340  68.570  1.00 106.42 ? 468 ASP   A OD2 1 
ATOM   3400 N N   . ASP   A 1 469 ? 71.988  99.031  64.420  1.00 110.93 ? 469 ASP   A N   1 
ATOM   3401 C CA  . ASP   A 1 469 ? 71.237  98.076  63.612  1.00 110.93 ? 469 ASP   A CA  1 
ATOM   3402 C C   . ASP   A 1 469 ? 69.919  97.689  64.271  1.00 110.93 ? 469 ASP   A C   1 
ATOM   3403 O O   . ASP   A 1 469 ? 68.939  97.408  63.572  1.00 110.93 ? 469 ASP   A O   1 
ATOM   3404 C CB  . ASP   A 1 469 ? 72.085  96.831  63.351  1.00 110.93 ? 469 ASP   A CB  1 
ATOM   3405 C CG  . ASP   A 1 469 ? 73.350  97.142  62.575  1.00 110.93 ? 469 ASP   A CG  1 
ATOM   3406 O OD1 . ASP   A 1 469 ? 73.407  98.211  61.931  1.00 110.93 ? 469 ASP   A OD1 1 
ATOM   3407 O OD2 . ASP   A 1 469 ? 74.288  96.318  62.611  1.00 110.93 ? 469 ASP   A OD2 1 
ATOM   3408 N N   . ASN   A 1 470 ? 69.874  97.666  65.606  1.00 109.12 ? 470 ASN   A N   1 
ATOM   3409 C CA  . ASN   A 1 470 ? 68.650  97.300  66.310  1.00 109.12 ? 470 ASN   A CA  1 
ATOM   3410 C C   . ASN   A 1 470 ? 67.578  98.378  66.223  1.00 109.12 ? 470 ASN   A C   1 
ATOM   3411 O O   . ASN   A 1 470 ? 66.417  98.104  66.545  1.00 109.12 ? 470 ASN   A O   1 
ATOM   3412 C CB  . ASN   A 1 470 ? 68.956  97.000  67.779  1.00 109.12 ? 470 ASN   A CB  1 
ATOM   3413 C CG  . ASN   A 1 470 ? 69.520  95.609  67.985  1.00 109.12 ? 470 ASN   A CG  1 
ATOM   3414 O OD1 . ASN   A 1 470 ? 69.872  94.921  67.027  1.00 109.12 ? 470 ASN   A OD1 1 
ATOM   3415 N ND2 . ASN   A 1 470 ? 69.608  95.187  69.240  1.00 109.12 ? 470 ASN   A ND2 1 
ATOM   3416 N N   . GLY   A 1 471 ? 67.933  99.588  65.803  1.00 104.04 ? 471 GLY   A N   1 
ATOM   3417 C CA  . GLY   A 1 471 ? 66.983  100.676 65.729  1.00 104.04 ? 471 GLY   A CA  1 
ATOM   3418 C C   . GLY   A 1 471 ? 66.899  101.543 66.963  1.00 104.04 ? 471 GLY   A C   1 
ATOM   3419 O O   . GLY   A 1 471 ? 66.017  102.407 67.032  1.00 104.04 ? 471 GLY   A O   1 
ATOM   3420 N N   . ILE   A 1 472 ? 67.783  101.344 67.937  1.00 99.30  ? 472 ILE   A N   1 
ATOM   3421 C CA  . ILE   A 1 472 ? 67.804  102.134 69.162  1.00 99.30  ? 472 ILE   A CA  1 
ATOM   3422 C C   . ILE   A 1 472 ? 68.927  103.160 69.062  1.00 99.30  ? 472 ILE   A C   1 
ATOM   3423 O O   . ILE   A 1 472 ? 70.043  102.840 68.635  1.00 99.30  ? 472 ILE   A O   1 
ATOM   3424 C CB  . ILE   A 1 472 ? 67.957  101.235 70.404  1.00 99.30  ? 472 ILE   A CB  1 
ATOM   3425 C CG1 . ILE   A 1 472 ? 68.005  102.076 71.682  1.00 99.30  ? 472 ILE   A CG1 1 
ATOM   3426 C CG2 . ILE   A 1 472 ? 69.157  100.296 70.284  1.00 99.30  ? 472 ILE   A CG2 1 
ATOM   3427 C CD1 . ILE   A 1 472 ? 67.843  101.271 72.939  1.00 99.30  ? 472 ILE   A CD1 1 
ATOM   3428 N N   . TYR   A 1 473 ? 68.620  104.403 69.421  1.00 97.05  ? 473 TYR   A N   1 
ATOM   3429 C CA  . TYR   A 1 473 ? 69.588  105.482 69.291  1.00 97.05  ? 473 TYR   A CA  1 
ATOM   3430 C C   . TYR   A 1 473 ? 70.678  105.351 70.348  1.00 97.05  ? 473 TYR   A C   1 
ATOM   3431 O O   . TYR   A 1 473 ? 70.389  105.181 71.536  1.00 97.05  ? 473 TYR   A O   1 
ATOM   3432 C CB  . TYR   A 1 473 ? 68.879  106.829 69.410  1.00 97.05  ? 473 TYR   A CB  1 
ATOM   3433 C CG  . TYR   A 1 473 ? 67.845  107.049 68.329  1.00 97.05  ? 473 TYR   A CG  1 
ATOM   3434 C CD1 . TYR   A 1 473 ? 68.133  106.767 67.001  1.00 97.05  ? 473 TYR   A CD1 1 
ATOM   3435 C CD2 . TYR   A 1 473 ? 66.573  107.509 68.640  1.00 97.05  ? 473 TYR   A CD2 1 
ATOM   3436 C CE1 . TYR   A 1 473 ? 67.191  106.959 66.009  1.00 97.05  ? 473 TYR   A CE1 1 
ATOM   3437 C CE2 . TYR   A 1 473 ? 65.623  107.705 67.655  1.00 97.05  ? 473 TYR   A CE2 1 
ATOM   3438 C CZ  . TYR   A 1 473 ? 65.937  107.427 66.342  1.00 97.05  ? 473 TYR   A CZ  1 
ATOM   3439 O OH  . TYR   A 1 473 ? 64.995  107.617 65.358  1.00 97.05  ? 473 TYR   A OH  1 
ATOM   3440 N N   . ASN   A 1 474 ? 71.931  105.431 69.911  1.00 91.73  ? 474 ASN   A N   1 
ATOM   3441 C CA  . ASN   A 1 474 ? 73.090  105.290 70.782  1.00 91.73  ? 474 ASN   A CA  1 
ATOM   3442 C C   . ASN   A 1 474 ? 73.781  106.636 70.933  1.00 91.73  ? 474 ASN   A C   1 
ATOM   3443 O O   . ASN   A 1 474 ? 73.998  107.342 69.943  1.00 91.73  ? 474 ASN   A O   1 
ATOM   3444 C CB  . ASN   A 1 474 ? 74.068  104.252 70.229  1.00 91.73  ? 474 ASN   A CB  1 
ATOM   3445 C CG  . ASN   A 1 474 ? 73.609  102.831 70.479  1.00 91.73  ? 474 ASN   A CG  1 
ATOM   3446 O OD1 . ASN   A 1 474 ? 72.422  102.523 70.378  1.00 91.73  ? 474 ASN   A OD1 1 
ATOM   3447 N ND2 . ASN   A 1 474 ? 74.550  101.955 70.811  1.00 91.73  ? 474 ASN   A ND2 1 
ATOM   3448 N N   . GLN   A 1 475 ? 74.124  106.986 72.170  1.00 75.41  ? 475 GLN   A N   1 
ATOM   3449 C CA  . GLN   A 1 475 ? 74.752  108.267 72.455  1.00 75.41  ? 475 GLN   A CA  1 
ATOM   3450 C C   . GLN   A 1 475 ? 76.254  108.193 72.215  1.00 75.41  ? 475 GLN   A C   1 
ATOM   3451 O O   . GLN   A 1 475 ? 76.929  107.287 72.713  1.00 75.41  ? 475 GLN   A O   1 
ATOM   3452 C CB  . GLN   A 1 475 ? 74.472  108.685 73.897  1.00 75.41  ? 475 GLN   A CB  1 
ATOM   3453 C CG  . GLN   A 1 475 ? 72.998  108.764 74.254  1.00 75.41  ? 475 GLN   A CG  1 
ATOM   3454 C CD  . GLN   A 1 475 ? 72.344  110.055 73.800  1.00 75.41  ? 475 GLN   A CD  1 
ATOM   3455 O OE1 . GLN   A 1 475 ? 72.965  110.885 73.138  1.00 75.41  ? 475 GLN   A OE1 1 
ATOM   3456 N NE2 . GLN   A 1 475 ? 71.078  110.229 74.158  1.00 75.41  ? 475 GLN   A NE2 1 
ATOM   3457 N N   . LYS   A 1 476 ? 76.775  109.152 71.450  1.00 71.79  ? 476 LYS   A N   1 
ATOM   3458 C CA  . LYS   A 1 476 ? 78.210  109.298 71.253  1.00 71.79  ? 476 LYS   A CA  1 
ATOM   3459 C C   . LYS   A 1 476 ? 78.813  110.353 72.174  1.00 71.79  ? 476 LYS   A C   1 
ATOM   3460 O O   . LYS   A 1 476 ? 80.018  110.311 72.445  1.00 71.79  ? 476 LYS   A O   1 
ATOM   3461 C CB  . LYS   A 1 476 ? 78.495  109.643 69.784  1.00 71.79  ? 476 LYS   A CB  1 
ATOM   3462 C CG  . LYS   A 1 476 ? 79.960  109.698 69.383  1.00 71.79  ? 476 LYS   A CG  1 
ATOM   3463 C CD  . LYS   A 1 476 ? 80.106  110.109 67.929  1.00 71.79  ? 476 LYS   A CD  1 
ATOM   3464 C CE  . LYS   A 1 476 ? 79.705  108.977 66.998  1.00 71.79  ? 476 LYS   A CE  1 
ATOM   3465 N NZ  . LYS   A 1 476 ? 79.950  109.315 65.570  1.00 71.79  ? 476 LYS   A NZ  1 
ATOM   3466 N N   . PHE   A 1 477 ? 77.993  111.271 72.675  1.00 64.82  ? 477 PHE   A N   1 
ATOM   3467 C CA  . PHE   A 1 477 ? 78.428  112.249 73.657  1.00 64.82  ? 477 PHE   A CA  1 
ATOM   3468 C C   . PHE   A 1 477 ? 78.797  111.553 74.968  1.00 64.82  ? 477 PHE   A C   1 
ATOM   3469 O O   . PHE   A 1 477 ? 78.173  110.559 75.348  1.00 64.82  ? 477 PHE   A O   1 
ATOM   3470 C CB  . PHE   A 1 477 ? 77.307  113.262 73.892  1.00 64.82  ? 477 PHE   A CB  1 
ATOM   3471 C CG  . PHE   A 1 477 ? 77.698  114.436 74.740  1.00 64.82  ? 477 PHE   A CG  1 
ATOM   3472 C CD1 . PHE   A 1 477 ? 78.393  115.501 74.195  1.00 64.82  ? 477 PHE   A CD1 1 
ATOM   3473 C CD2 . PHE   A 1 477 ? 77.352  114.483 76.080  1.00 64.82  ? 477 PHE   A CD2 1 
ATOM   3474 C CE1 . PHE   A 1 477 ? 78.747  116.585 74.974  1.00 64.82  ? 477 PHE   A CE1 1 
ATOM   3475 C CE2 . PHE   A 1 477 ? 77.703  115.563 76.864  1.00 64.82  ? 477 PHE   A CE2 1 
ATOM   3476 C CZ  . PHE   A 1 477 ? 78.400  116.616 76.311  1.00 64.82  ? 477 PHE   A CZ  1 
ATOM   3477 N N   . PRO   A 1 478 ? 79.818  112.049 75.677  1.00 56.97  ? 478 PRO   A N   1 
ATOM   3478 C CA  . PRO   A 1 478 ? 80.169  111.454 76.974  1.00 56.97  ? 478 PRO   A CA  1 
ATOM   3479 C C   . PRO   A 1 478 ? 79.144  111.742 78.060  1.00 56.97  ? 478 PRO   A C   1 
ATOM   3480 O O   . PRO   A 1 478 ? 79.396  112.545 78.964  1.00 56.97  ? 478 PRO   A O   1 
ATOM   3481 C CB  . PRO   A 1 478 ? 81.520  112.105 77.292  1.00 56.97  ? 478 PRO   A CB  1 
ATOM   3482 C CG  . PRO   A 1 478 ? 81.475  113.406 76.576  1.00 56.97  ? 478 PRO   A CG  1 
ATOM   3483 C CD  . PRO   A 1 478 ? 80.778  113.095 75.284  1.00 56.97  ? 478 PRO   A CD  1 
ATOM   3484 N N   . PHE   A 1 479 ? 77.987  111.083 77.987  1.00 54.36  ? 479 PHE   A N   1 
ATOM   3485 C CA  . PHE   A 1 479 ? 76.914  111.358 78.936  1.00 54.36  ? 479 PHE   A CA  1 
ATOM   3486 C C   . PHE   A 1 479 ? 77.124  110.660 80.274  1.00 54.36  ? 479 PHE   A C   1 
ATOM   3487 O O   . PHE   A 1 479 ? 76.584  111.113 81.286  1.00 54.36  ? 479 PHE   A O   1 
ATOM   3488 C CB  . PHE   A 1 479 ? 75.561  110.965 78.333  1.00 54.36  ? 479 PHE   A CB  1 
ATOM   3489 C CG  . PHE   A 1 479 ? 75.315  109.482 78.282  1.00 54.36  ? 479 PHE   A CG  1 
ATOM   3490 C CD1 . PHE   A 1 479 ? 75.906  108.700 77.305  1.00 54.36  ? 479 PHE   A CD1 1 
ATOM   3491 C CD2 . PHE   A 1 479 ? 74.474  108.875 79.200  1.00 54.36  ? 479 PHE   A CD2 1 
ATOM   3492 C CE1 . PHE   A 1 479 ? 75.676  107.340 77.254  1.00 54.36  ? 479 PHE   A CE1 1 
ATOM   3493 C CE2 . PHE   A 1 479 ? 74.241  107.517 79.153  1.00 54.36  ? 479 PHE   A CE2 1 
ATOM   3494 C CZ  . PHE   A 1 479 ? 74.842  106.749 78.179  1.00 54.36  ? 479 PHE   A CZ  1 
ATOM   3495 N N   . LYS   A 1 480 ? 77.891  109.568 80.308  1.00 50.95  ? 480 LYS   A N   1 
ATOM   3496 C CA  . LYS   A 1 480 ? 78.126  108.867 81.568  1.00 50.95  ? 480 LYS   A CA  1 
ATOM   3497 C C   . LYS   A 1 480 ? 79.074  109.651 82.470  1.00 50.95  ? 480 LYS   A C   1 
ATOM   3498 O O   . LYS   A 1 480 ? 78.833  109.790 83.676  1.00 50.95  ? 480 LYS   A O   1 
ATOM   3499 C CB  . LYS   A 1 480 ? 78.677  107.469 81.288  1.00 50.95  ? 480 LYS   A CB  1 
ATOM   3500 C CG  . LYS   A 1 480 ? 77.626  106.469 80.848  1.00 50.95  ? 480 LYS   A CG  1 
ATOM   3501 C CD  . LYS   A 1 480 ? 78.267  105.240 80.232  1.00 50.95  ? 480 LYS   A CD  1 
ATOM   3502 C CE  . LYS   A 1 480 ? 77.222  104.267 79.718  1.00 50.95  ? 480 LYS   A CE  1 
ATOM   3503 N NZ  . LYS   A 1 480 ? 77.841  103.144 78.966  1.00 50.95  ? 480 LYS   A NZ  1 
ATOM   3504 N N   . THR   A 1 481 ? 80.165  110.168 81.899  1.00 49.57  ? 481 THR   A N   1 
ATOM   3505 C CA  . THR   A 1 481 ? 81.071  111.023 82.660  1.00 49.57  ? 481 THR   A CA  1 
ATOM   3506 C C   . THR   A 1 481 ? 80.375  112.314 83.074  1.00 49.57  ? 481 THR   A C   1 
ATOM   3507 O O   . THR   A 1 481 ? 80.587  112.816 84.186  1.00 49.57  ? 481 THR   A O   1 
ATOM   3508 C CB  . THR   A 1 481 ? 82.325  111.312 81.833  1.00 49.57  ? 481 THR   A CB  1 
ATOM   3509 O OG1 . THR   A 1 481 ? 83.039  110.090 81.613  1.00 49.57  ? 481 THR   A OG1 1 
ATOM   3510 C CG2 . THR   A 1 481 ? 83.243  112.291 82.548  1.00 49.57  ? 481 THR   A CG2 1 
ATOM   3511 N N   . LEU   A 1 482 ? 79.522  112.849 82.195  1.00 50.41  ? 482 LEU   A N   1 
ATOM   3512 C CA  . LEU   A 1 482 ? 78.710  114.008 82.550  1.00 50.41  ? 482 LEU   A CA  1 
ATOM   3513 C C   . LEU   A 1 482 ? 77.776  113.691 83.710  1.00 50.41  ? 482 LEU   A C   1 
ATOM   3514 O O   . LEU   A 1 482 ? 77.580  114.522 84.599  1.00 50.41  ? 482 LEU   A O   1 
ATOM   3515 C CB  . LEU   A 1 482 ? 77.916  114.484 81.334  1.00 50.41  ? 482 LEU   A CB  1 
ATOM   3516 C CG  . LEU   A 1 482 ? 76.887  115.593 81.568  1.00 50.41  ? 482 LEU   A CG  1 
ATOM   3517 C CD1 . LEU   A 1 482 ? 77.573  116.893 81.946  1.00 50.41  ? 482 LEU   A CD1 1 
ATOM   3518 C CD2 . LEU   A 1 482 ? 76.014  115.783 80.342  1.00 50.41  ? 482 LEU   A CD2 1 
ATOM   3519 N N   . ALA   A 1 483 ? 77.198  112.487 83.721  1.00 50.89  ? 483 ALA   A N   1 
ATOM   3520 C CA  . ALA   A 1 483 ? 76.338  112.078 84.827  1.00 50.89  ? 483 ALA   A CA  1 
ATOM   3521 C C   . ALA   A 1 483 ? 77.120  111.970 86.129  1.00 50.89  ? 483 ALA   A C   1 
ATOM   3522 O O   . ALA   A 1 483 ? 76.631  112.377 87.188  1.00 50.89  ? 483 ALA   A O   1 
ATOM   3523 C CB  . ALA   A 1 483 ? 75.662  110.748 84.500  1.00 50.89  ? 483 ALA   A CB  1 
ATOM   3524 N N   . MET   A 1 484 ? 78.337  111.423 86.068  1.00 50.30  ? 484 MET   A N   1 
ATOM   3525 C CA  . MET   A 1 484 ? 79.171  111.322 87.266  1.00 50.30  ? 484 MET   A CA  1 
ATOM   3526 C C   . MET   A 1 484 ? 79.517  112.704 87.813  1.00 50.30  ? 484 MET   A C   1 
ATOM   3527 O O   . MET   A 1 484 ? 79.405  112.957 89.021  1.00 50.30  ? 484 MET   A O   1 
ATOM   3528 C CB  . MET   A 1 484 ? 80.452  110.549 86.958  1.00 50.30  ? 484 MET   A CB  1 
ATOM   3529 C CG  . MET   A 1 484 ? 81.279  110.222 88.192  1.00 50.30  ? 484 MET   A CG  1 
ATOM   3530 S SD  . MET   A 1 484 ? 82.609  111.387 88.564  1.00 50.30  ? 484 MET   A SD  1 
ATOM   3531 C CE  . MET   A 1 484 ? 83.616  111.282 87.093  1.00 50.30  ? 484 MET   A CE  1 
ATOM   3532 N N   . VAL   A 1 485 ? 79.940  113.612 86.930  1.00 51.93  ? 485 VAL   A N   1 
ATOM   3533 C CA  . VAL   A 1 485 ? 80.318  114.956 87.357  1.00 51.93  ? 485 VAL   A CA  1 
ATOM   3534 C C   . VAL   A 1 485 ? 79.101  115.713 87.876  1.00 51.93  ? 485 VAL   A C   1 
ATOM   3535 O O   . VAL   A 1 485 ? 79.190  116.460 88.859  1.00 51.93  ? 485 VAL   A O   1 
ATOM   3536 C CB  . VAL   A 1 485 ? 81.014  115.700 86.201  1.00 51.93  ? 485 VAL   A CB  1 
ATOM   3537 C CG1 . VAL   A 1 485 ? 81.240  117.161 86.547  1.00 51.93  ? 485 VAL   A CG1 1 
ATOM   3538 C CG2 . VAL   A 1 485 ? 82.336  115.034 85.873  1.00 51.93  ? 485 VAL   A CG2 1 
ATOM   3539 N N   . THR   A 1 486 ? 77.942  115.515 87.243  1.00 54.65  ? 486 THR   A N   1 
ATOM   3540 C CA  . THR   A 1 486 ? 76.713  116.145 87.708  1.00 54.65  ? 486 THR   A CA  1 
ATOM   3541 C C   . THR   A 1 486 ? 76.316  115.628 89.082  1.00 54.65  ? 486 THR   A C   1 
ATOM   3542 O O   . THR   A 1 486 ? 75.883  116.403 89.937  1.00 54.65  ? 486 THR   A O   1 
ATOM   3543 C CB  . THR   A 1 486 ? 75.590  115.907 86.699  1.00 54.65  ? 486 THR   A CB  1 
ATOM   3544 O OG1 . THR   A 1 486 ? 76.024  116.319 85.398  1.00 54.65  ? 486 THR   A OG1 1 
ATOM   3545 C CG2 . THR   A 1 486 ? 74.351  116.699 87.080  1.00 54.65  ? 486 THR   A CG2 1 
ATOM   3546 N N   . SER   A 1 487 ? 76.464  114.321 89.317  1.00 57.74  ? 487 SER   A N   1 
ATOM   3547 C CA  . SER   A 1 487 ? 76.166  113.763 90.632  1.00 57.74  ? 487 SER   A CA  1 
ATOM   3548 C C   . SER   A 1 487 ? 77.098  114.327 91.697  1.00 57.74  ? 487 SER   A C   1 
ATOM   3549 O O   . SER   A 1 487 ? 76.653  114.690 92.792  1.00 57.74  ? 487 SER   A O   1 
ATOM   3550 C CB  . SER   A 1 487 ? 76.265  112.239 90.587  1.00 57.74  ? 487 SER   A CB  1 
ATOM   3551 O OG  . SER   A 1 487 ? 76.147  111.680 91.882  1.00 57.74  ? 487 SER   A OG  1 
ATOM   3552 N N   . PHE   A 1 488 ? 78.393  114.427 91.384  1.00 60.59  ? 488 PHE   A N   1 
ATOM   3553 C CA  . PHE   A 1 488 ? 79.362  114.964 92.338  1.00 60.59  ? 488 PHE   A CA  1 
ATOM   3554 C C   . PHE   A 1 488 ? 79.065  116.427 92.667  1.00 60.59  ? 488 PHE   A C   1 
ATOM   3555 O O   . PHE   A 1 488 ? 79.011  116.821 93.845  1.00 60.59  ? 488 PHE   A O   1 
ATOM   3556 C CB  . PHE   A 1 488 ? 80.770  114.804 91.762  1.00 60.59  ? 488 PHE   A CB  1 
ATOM   3557 C CG  . PHE   A 1 488 ? 81.868  115.258 92.678  1.00 60.59  ? 488 PHE   A CG  1 
ATOM   3558 C CD1 . PHE   A 1 488 ? 82.027  114.689 93.929  1.00 60.59  ? 488 PHE   A CD1 1 
ATOM   3559 C CD2 . PHE   A 1 488 ? 82.761  116.236 92.274  1.00 60.59  ? 488 PHE   A CD2 1 
ATOM   3560 C CE1 . PHE   A 1 488 ? 83.046  115.100 94.768  1.00 60.59  ? 488 PHE   A CE1 1 
ATOM   3561 C CE2 . PHE   A 1 488 ? 83.781  116.650 93.107  1.00 60.59  ? 488 PHE   A CE2 1 
ATOM   3562 C CZ  . PHE   A 1 488 ? 83.924  116.079 94.355  1.00 60.59  ? 488 PHE   A CZ  1 
ATOM   3563 N N   . LEU   A 1 489 ? 78.845  117.242 91.632  1.00 61.13  ? 489 LEU   A N   1 
ATOM   3564 C CA  . LEU   A 1 489 ? 78.572  118.660 91.838  1.00 61.13  ? 489 LEU   A CA  1 
ATOM   3565 C C   . LEU   A 1 489 ? 77.234  118.876 92.532  1.00 61.13  ? 489 LEU   A C   1 
ATOM   3566 O O   . LEU   A 1 489 ? 77.103  119.784 93.357  1.00 61.13  ? 489 LEU   A O   1 
ATOM   3567 C CB  . LEU   A 1 489 ? 78.613  119.402 90.504  1.00 61.13  ? 489 LEU   A CB  1 
ATOM   3568 C CG  . LEU   A 1 489 ? 80.002  119.571 89.891  1.00 61.13  ? 489 LEU   A CG  1 
ATOM   3569 C CD1 . LEU   A 1 489 ? 79.916  120.299 88.562  1.00 61.13  ? 489 LEU   A CD1 1 
ATOM   3570 C CD2 . LEU   A 1 489 ? 80.916  120.310 90.852  1.00 61.13  ? 489 LEU   A CD2 1 
ATOM   3571 N N   . THR   A 1 490 ? 76.229  118.057 92.210  1.00 66.46  ? 490 THR   A N   1 
ATOM   3572 C CA  . THR   A 1 490 ? 74.942  118.145 92.886  1.00 66.46  ? 490 THR   A CA  1 
ATOM   3573 C C   . THR   A 1 490 ? 75.072  117.786 94.357  1.00 66.46  ? 490 THR   A C   1 
ATOM   3574 O O   . THR   A 1 490 ? 74.469  118.440 95.212  1.00 66.46  ? 490 THR   A O   1 
ATOM   3575 C CB  . THR   A 1 490 ? 73.927  117.232 92.198  1.00 66.46  ? 490 THR   A CB  1 
ATOM   3576 O OG1 . THR   A 1 490 ? 73.864  117.550 90.803  1.00 66.46  ? 490 THR   A OG1 1 
ATOM   3577 C CG2 . THR   A 1 490 ? 72.547  117.410 92.807  1.00 66.46  ? 490 THR   A CG2 1 
ATOM   3578 N N   . ASN   A 1 491 ? 75.866  116.757 94.668  1.00 66.91  ? 491 ASN   A N   1 
ATOM   3579 C CA  . ASN   A 1 491 ? 76.126  116.401 96.059  1.00 66.91  ? 491 ASN   A CA  1 
ATOM   3580 C C   . ASN   A 1 491 ? 76.722  117.580 96.815  1.00 66.91  ? 491 ASN   A C   1 
ATOM   3581 O O   . ASN   A 1 491 ? 76.199  117.988 97.861  1.00 66.91  ? 491 ASN   A O   1 
ATOM   3582 C CB  . ASN   A 1 491 ? 77.059  115.188 96.108  1.00 66.91  ? 491 ASN   A CB  1 
ATOM   3583 C CG  . ASN   A 1 491 ? 77.089  114.513 97.469  1.00 66.91  ? 491 ASN   A CG  1 
ATOM   3584 O OD1 . ASN   A 1 491 ? 76.761  115.112 98.491  1.00 66.91  ? 491 ASN   A OD1 1 
ATOM   3585 N ND2 . ASN   A 1 491 ? 77.490  113.248 97.483  1.00 66.91  ? 491 ASN   A ND2 1 
ATOM   3586 N N   . ILE   A 1 492 ? 77.787  118.174 96.266  1.00 71.91  ? 492 ILE   A N   1 
ATOM   3587 C CA  . ILE   A 1 492 ? 78.450  119.295 96.937  1.00 71.91  ? 492 ILE   A CA  1 
ATOM   3588 C C   . ILE   A 1 492 ? 77.498  120.480 97.085  1.00 71.91  ? 492 ILE   A C   1 
ATOM   3589 O O   . ILE   A 1 492 ? 77.368  121.068 98.170  1.00 71.91  ? 492 ILE   A O   1 
ATOM   3590 C CB  . ILE   A 1 492 ? 79.726  119.697 96.176  1.00 71.91  ? 492 ILE   A CB  1 
ATOM   3591 C CG1 . ILE   A 1 492 ? 80.703  118.527 96.100  1.00 71.91  ? 492 ILE   A CG1 1 
ATOM   3592 C CG2 . ILE   A 1 492 ? 80.385  120.899 96.829  1.00 71.91  ? 492 ILE   A CG2 1 
ATOM   3593 C CD1 . ILE   A 1 492 ? 81.965  118.860 95.351  1.00 71.91  ? 492 ILE   A CD1 1 
ATOM   3594 N N   . CYS   A 1 493 ? 76.802  120.831 96.000  1.00 78.68  ? 493 CYS   A N   1 
ATOM   3595 C CA  . CYS   A 1 493 ? 75.968  122.026 95.988  1.00 78.68  ? 493 CYS   A CA  1 
ATOM   3596 C C   . CYS   A 1 493 ? 74.782  121.888 96.932  1.00 78.68  ? 493 CYS   A C   1 
ATOM   3597 O O   . CYS   A 1 493 ? 74.495  122.801 97.710  1.00 78.68  ? 493 CYS   A O   1 
ATOM   3598 C CB  . CYS   A 1 493 ? 75.491  122.315 94.565  1.00 78.68  ? 493 CYS   A CB  1 
ATOM   3599 S SG  . CYS   A 1 493 ? 76.664  123.254 93.563  1.00 78.68  ? 493 CYS   A SG  1 
ATOM   3600 N N   . ILE   A 1 494 ? 74.084  120.751 96.884  1.00 79.99  ? 494 ILE   A N   1 
ATOM   3601 C CA  . ILE   A 1 494 ? 72.927  120.554 97.749  1.00 79.99  ? 494 ILE   A CA  1 
ATOM   3602 C C   . ILE   A 1 494 ? 73.358  120.437 99.205  1.00 79.99  ? 494 ILE   A C   1 
ATOM   3603 O O   . ILE   A 1 494 ? 72.678  120.952 100.101 1.00 79.99  ? 494 ILE   A O   1 
ATOM   3604 C CB  . ILE   A 1 494 ? 72.111  119.333 97.281  1.00 79.99  ? 494 ILE   A CB  1 
ATOM   3605 C CG1 . ILE   A 1 494 ? 71.563  119.567 95.870  1.00 79.99  ? 494 ILE   A CG1 1 
ATOM   3606 C CG2 . ILE   A 1 494 ? 70.964  119.040 98.232  1.00 79.99  ? 494 ILE   A CG2 1 
ATOM   3607 C CD1 . ILE   A 1 494 ? 70.930  120.928 95.663  1.00 79.99  ? 494 ILE   A CD1 1 
ATOM   3608 N N   . SER   A 1 495 ? 74.507  119.801 99.469  1.00 83.10  ? 495 SER   A N   1 
ATOM   3609 C CA  . SER   A 1 495 ? 74.999  119.708 100.840 1.00 83.10  ? 495 SER   A CA  1 
ATOM   3610 C C   . SER   A 1 495 ? 75.267  121.089 101.427 1.00 83.10  ? 495 SER   A C   1 
ATOM   3611 O O   . SER   A 1 495 ? 74.753  121.430 102.501 1.00 83.10  ? 495 SER   A O   1 
ATOM   3612 C CB  . SER   A 1 495 ? 76.265  118.853 100.880 1.00 83.10  ? 495 SER   A CB  1 
ATOM   3613 O OG  . SER   A 1 495 ? 75.983  117.507 100.545 1.00 83.10  ? 495 SER   A OG  1 
ATOM   3614 N N   . TYR   A 1 496 ? 76.045  121.914 100.719 1.00 88.93  ? 496 TYR   A N   1 
ATOM   3615 C CA  . TYR   A 1 496 ? 76.361  123.234 101.260 1.00 88.93  ? 496 TYR   A CA  1 
ATOM   3616 C C   . TYR   A 1 496 ? 75.152  124.165 101.255 1.00 88.93  ? 496 TYR   A C   1 
ATOM   3617 O O   . TYR   A 1 496 ? 75.019  125.003 102.156 1.00 88.93  ? 496 TYR   A O   1 
ATOM   3618 C CB  . TYR   A 1 496 ? 77.535  123.852 100.502 1.00 88.93  ? 496 TYR   A CB  1 
ATOM   3619 C CG  . TYR   A 1 496 ? 78.863  123.228 100.869 1.00 88.93  ? 496 TYR   A CG  1 
ATOM   3620 C CD1 . TYR   A 1 496 ? 79.432  123.454 102.116 1.00 88.93  ? 496 TYR   A CD1 1 
ATOM   3621 C CD2 . TYR   A 1 496 ? 79.545  122.413 99.978  1.00 88.93  ? 496 TYR   A CD2 1 
ATOM   3622 C CE1 . TYR   A 1 496 ? 80.643  122.887 102.463 1.00 88.93  ? 496 TYR   A CE1 1 
ATOM   3623 C CE2 . TYR   A 1 496 ? 80.758  121.841 100.316 1.00 88.93  ? 496 TYR   A CE2 1 
ATOM   3624 C CZ  . TYR   A 1 496 ? 81.301  122.082 101.559 1.00 88.93  ? 496 TYR   A CZ  1 
ATOM   3625 O OH  . TYR   A 1 496 ? 82.507  121.517 101.901 1.00 88.93  ? 496 TYR   A OH  1 
ATOM   3626 N N   . LEU   A 1 497 ? 74.253  124.024 100.277 1.00 95.97  ? 497 LEU   A N   1 
ATOM   3627 C CA  . LEU   A 1 497 ? 73.038  124.830 100.268 1.00 95.97  ? 497 LEU   A CA  1 
ATOM   3628 C C   . LEU   A 1 497 ? 72.151  124.498 101.458 1.00 95.97  ? 497 LEU   A C   1 
ATOM   3629 O O   . LEU   A 1 497 ? 71.607  125.400 102.102 1.00 95.97  ? 497 LEU   A O   1 
ATOM   3630 C CB  . LEU   A 1 497 ? 72.279  124.619 98.959  1.00 95.97  ? 497 LEU   A CB  1 
ATOM   3631 C CG  . LEU   A 1 497 ? 70.982  125.412 98.791  1.00 95.97  ? 497 LEU   A CG  1 
ATOM   3632 C CD1 . LEU   A 1 497 ? 71.269  126.905 98.766  1.00 95.97  ? 497 LEU   A CD1 1 
ATOM   3633 C CD2 . LEU   A 1 497 ? 70.247  124.982 97.532  1.00 95.97  ? 497 LEU   A CD2 1 
ATOM   3634 N N   . ALA   A 1 498 ? 72.000  123.209 101.773 1.00 99.13  ? 498 ALA   A N   1 
ATOM   3635 C CA  . ALA   A 1 498 ? 71.214  122.817 102.936 1.00 99.13  ? 498 ALA   A CA  1 
ATOM   3636 C C   . ALA   A 1 498 ? 71.877  123.273 104.227 1.00 99.13  ? 498 ALA   A C   1 
ATOM   3637 O O   . ALA   A 1 498 ? 71.189  123.676 105.173 1.00 99.13  ? 498 ALA   A O   1 
ATOM   3638 C CB  . ALA   A 1 498 ? 71.008  121.306 102.940 1.00 99.13  ? 498 ALA   A CB  1 
ATOM   3639 N N   . LYS   A 1 499 ? 73.213  123.218 104.283 1.00 101.34 ? 499 LYS   A N   1 
ATOM   3640 C CA  . LYS   A 1 499 ? 73.921  123.750 105.444 1.00 101.34 ? 499 LYS   A CA  1 
ATOM   3641 C C   . LYS   A 1 499 ? 73.631  125.233 105.633 1.00 101.34 ? 499 LYS   A C   1 
ATOM   3642 O O   . LYS   A 1 499 ? 73.354  125.679 106.753 1.00 101.34 ? 499 LYS   A O   1 
ATOM   3643 C CB  . LYS   A 1 499 ? 75.425  123.515 105.302 1.00 101.34 ? 499 LYS   A CB  1 
ATOM   3644 C CG  . LYS   A 1 499 ? 75.852  122.067 105.458 1.00 101.34 ? 499 LYS   A CG  1 
ATOM   3645 C CD  . LYS   A 1 499 ? 77.345  121.908 105.225 1.00 101.34 ? 499 LYS   A CD  1 
ATOM   3646 C CE  . LYS   A 1 499 ? 78.151  122.530 106.353 1.00 101.34 ? 499 LYS   A CE  1 
ATOM   3647 N NZ  . LYS   A 1 499 ? 77.984  121.786 107.632 1.00 101.34 ? 499 LYS   A NZ  1 
ATOM   3648 N N   . TYR   A 1 500 ? 73.663  126.008 104.545 1.00 113.98 ? 500 TYR   A N   1 
ATOM   3649 C CA  . TYR   A 1 500 ? 73.378  127.437 104.646 1.00 113.98 ? 500 TYR   A CA  1 
ATOM   3650 C C   . TYR   A 1 500 ? 71.926  127.699 105.034 1.00 113.98 ? 500 TYR   A C   1 
ATOM   3651 O O   . TYR   A 1 500 ? 71.647  128.607 105.826 1.00 113.98 ? 500 TYR   A O   1 
ATOM   3652 C CB  . TYR   A 1 500 ? 73.712  128.139 103.331 1.00 113.98 ? 500 TYR   A CB  1 
ATOM   3653 C CG  . TYR   A 1 500 ? 73.689  129.646 103.437 1.00 113.98 ? 500 TYR   A CG  1 
ATOM   3654 C CD1 . TYR   A 1 500 ? 74.614  130.319 104.226 1.00 113.98 ? 500 TYR   A CD1 1 
ATOM   3655 C CD2 . TYR   A 1 500 ? 72.741  130.397 102.753 1.00 113.98 ? 500 TYR   A CD2 1 
ATOM   3656 C CE1 . TYR   A 1 500 ? 74.597  131.697 104.329 1.00 113.98 ? 500 TYR   A CE1 1 
ATOM   3657 C CE2 . TYR   A 1 500 ? 72.717  131.776 102.849 1.00 113.98 ? 500 TYR   A CE2 1 
ATOM   3658 C CZ  . TYR   A 1 500 ? 73.647  132.420 103.639 1.00 113.98 ? 500 TYR   A CZ  1 
ATOM   3659 O OH  . TYR   A 1 500 ? 73.627  133.793 103.739 1.00 113.98 ? 500 TYR   A OH  1 
ATOM   3660 N N   . LEU   A 1 501 ? 70.988  126.923 104.479 1.00 114.63 ? 501 LEU   A N   1 
ATOM   3661 C CA  . LEU   A 1 501 ? 69.577  127.115 104.806 1.00 114.63 ? 501 LEU   A CA  1 
ATOM   3662 C C   . LEU   A 1 501 ? 69.294  126.808 106.271 1.00 114.63 ? 501 LEU   A C   1 
ATOM   3663 O O   . LEU   A 1 501 ? 68.546  127.539 106.930 1.00 114.63 ? 501 LEU   A O   1 
ATOM   3664 C CB  . LEU   A 1 501 ? 68.693  126.252 103.903 1.00 114.63 ? 501 LEU   A CB  1 
ATOM   3665 C CG  . LEU   A 1 501 ? 68.666  126.581 102.409 1.00 114.63 ? 501 LEU   A CG  1 
ATOM   3666 C CD1 . LEU   A 1 501 ? 67.855  125.545 101.648 1.00 114.63 ? 501 LEU   A CD1 1 
ATOM   3667 C CD2 . LEU   A 1 501 ? 68.113  127.978 102.175 1.00 114.63 ? 501 LEU   A CD2 1 
ATOM   3668 N N   . PHE   A 1 502 ? 69.876  125.731 106.800 1.00 117.69 ? 502 PHE   A N   1 
ATOM   3669 C CA  . PHE   A 1 502 ? 69.650  125.407 108.204 1.00 117.69 ? 502 PHE   A CA  1 
ATOM   3670 C C   . PHE   A 1 502 ? 70.434  126.316 109.144 1.00 117.69 ? 502 PHE   A C   1 
ATOM   3671 O O   . PHE   A 1 502 ? 70.015  126.514 110.290 1.00 117.69 ? 502 PHE   A O   1 
ATOM   3672 C CB  . PHE   A 1 502 ? 69.986  123.940 108.472 1.00 117.69 ? 502 PHE   A CB  1 
ATOM   3673 C CG  . PHE   A 1 502 ? 68.894  122.986 108.069 1.00 117.69 ? 502 PHE   A CG  1 
ATOM   3674 C CD1 . PHE   A 1 502 ? 67.825  122.742 108.916 1.00 117.69 ? 502 PHE   A CD1 1 
ATOM   3675 C CD2 . PHE   A 1 502 ? 68.937  122.332 106.849 1.00 117.69 ? 502 PHE   A CD2 1 
ATOM   3676 C CE1 . PHE   A 1 502 ? 66.818  121.866 108.551 1.00 117.69 ? 502 PHE   A CE1 1 
ATOM   3677 C CE2 . PHE   A 1 502 ? 67.934  121.456 106.479 1.00 117.69 ? 502 PHE   A CE2 1 
ATOM   3678 C CZ  . PHE   A 1 502 ? 66.873  121.222 107.331 1.00 117.69 ? 502 PHE   A CZ  1 
ATOM   3679 N N   . GLU   A 1 503 ? 71.563  126.873 108.695 1.00 120.11 ? 503 GLU   A N   1 
ATOM   3680 C CA  . GLU   A 1 503 ? 72.293  127.818 109.535 1.00 120.11 ? 503 GLU   A CA  1 
ATOM   3681 C C   . GLU   A 1 503 ? 71.581  129.163 109.609 1.00 120.11 ? 503 GLU   A C   1 
ATOM   3682 O O   . GLU   A 1 503 ? 71.463  129.749 110.692 1.00 120.11 ? 503 GLU   A O   1 
ATOM   3683 C CB  . GLU   A 1 503 ? 73.717  127.996 109.010 1.00 120.11 ? 503 GLU   A CB  1 
ATOM   3684 C CG  . GLU   A 1 503 ? 74.704  126.957 109.514 1.00 120.11 ? 503 GLU   A CG  1 
ATOM   3685 C CD  . GLU   A 1 503 ? 76.122  127.236 109.058 1.00 120.11 ? 503 GLU   A CD  1 
ATOM   3686 O OE1 . GLU   A 1 503 ? 76.302  127.658 107.896 1.00 120.11 ? 503 GLU   A OE1 1 
ATOM   3687 O OE2 . GLU   A 1 503 ? 77.057  127.036 109.862 1.00 120.11 ? 503 GLU   A OE2 1 
ATOM   3688 N N   . SER   A 1 504 ? 71.100  129.668 108.470 1.00 124.09 ? 504 SER   A N   1 
ATOM   3689 C CA  . SER   A 1 504 ? 70.470  130.983 108.440 1.00 124.09 ? 504 SER   A CA  1 
ATOM   3690 C C   . SER   A 1 504 ? 69.104  130.995 109.112 1.00 124.09 ? 504 SER   A C   1 
ATOM   3691 O O   . SER   A 1 504 ? 68.628  132.068 109.496 1.00 124.09 ? 504 SER   A O   1 
ATOM   3692 C CB  . SER   A 1 504 ? 70.340  131.470 106.996 1.00 124.09 ? 504 SER   A CB  1 
ATOM   3693 O OG  . SER   A 1 504 ? 70.023  132.850 106.949 1.00 124.09 ? 504 SER   A OG  1 
ATOM   3694 N N   . GLY   A 1 505 ? 68.468  129.839 109.263 1.00 124.93 ? 505 GLY   A N   1 
ATOM   3695 C CA  . GLY   A 1 505 ? 67.168  129.759 109.891 1.00 124.93 ? 505 GLY   A CA  1 
ATOM   3696 C C   . GLY   A 1 505 ? 65.988  129.753 108.948 1.00 124.93 ? 505 GLY   A C   1 
ATOM   3697 O O   . GLY   A 1 505 ? 64.851  129.900 109.412 1.00 124.93 ? 505 GLY   A O   1 
ATOM   3698 N N   . THR   A 1 506 ? 66.219  129.604 107.640 1.00 126.00 ? 506 THR   A N   1 
ATOM   3699 C CA  . THR   A 1 506 ? 65.111  129.526 106.693 1.00 126.00 ? 506 THR   A CA  1 
ATOM   3700 C C   . THR   A 1 506 ? 64.270  128.277 106.931 1.00 126.00 ? 506 THR   A C   1 
ATOM   3701 O O   . THR   A 1 506 ? 63.036  128.327 106.864 1.00 126.00 ? 506 THR   A O   1 
ATOM   3702 C CB  . THR   A 1 506 ? 65.642  129.548 105.260 1.00 126.00 ? 506 THR   A CB  1 
ATOM   3703 O OG1 . THR   A 1 506 ? 66.654  130.556 105.139 1.00 126.00 ? 506 THR   A OG1 1 
ATOM   3704 C CG2 . THR   A 1 506 ? 64.518  129.851 104.280 1.00 126.00 ? 506 THR   A CG2 1 
ATOM   3705 N N   . LEU   A 1 507 ? 64.920  127.150 107.214 1.00 127.93 ? 507 LEU   A N   1 
ATOM   3706 C CA  . LEU   A 1 507 ? 64.234  125.902 107.500 1.00 127.93 ? 507 LEU   A CA  1 
ATOM   3707 C C   . LEU   A 1 507 ? 64.414  125.537 108.964 1.00 127.93 ? 507 LEU   A C   1 
ATOM   3708 O O   . LEU   A 1 507 ? 65.553  125.484 109.447 1.00 127.93 ? 507 LEU   A O   1 
ATOM   3709 C CB  . LEU   A 1 507 ? 64.767  124.776 106.609 1.00 127.93 ? 507 LEU   A CB  1 
ATOM   3710 C CG  . LEU   A 1 507 ? 64.745  125.050 105.103 1.00 127.93 ? 507 LEU   A CG  1 
ATOM   3711 C CD1 . LEU   A 1 507 ? 65.201  123.827 104.323 1.00 127.93 ? 507 LEU   A CD1 1 
ATOM   3712 C CD2 . LEU   A 1 507 ? 63.360  125.487 104.653 1.00 127.93 ? 507 LEU   A CD2 1 
ATOM   3713 N N   . PRO   A 1 508 ? 63.332  125.291 109.697 1.00 133.06 ? 508 PRO   A N   1 
ATOM   3714 C CA  . PRO   A 1 508 ? 63.447  124.986 111.129 1.00 133.06 ? 508 PRO   A CA  1 
ATOM   3715 C C   . PRO   A 1 508 ? 64.062  123.617 111.354 1.00 133.06 ? 508 PRO   A C   1 
ATOM   3716 O O   . PRO   A 1 508 ? 64.013  122.750 110.468 1.00 133.06 ? 508 PRO   A O   1 
ATOM   3717 C CB  . PRO   A 1 508 ? 61.991  125.031 111.617 1.00 133.06 ? 508 PRO   A CB  1 
ATOM   3718 C CG  . PRO   A 1 508 ? 61.182  124.720 110.409 1.00 133.06 ? 508 PRO   A CG  1 
ATOM   3719 C CD  . PRO   A 1 508 ? 61.932  125.292 109.239 1.00 133.06 ? 508 PRO   A CD  1 
ATOM   3720 N N   . PRO   A 1 509 ? 64.659  123.385 112.529 1.00 133.91 ? 509 PRO   A N   1 
ATOM   3721 C CA  . PRO   A 1 509 ? 65.231  122.060 112.825 1.00 133.91 ? 509 PRO   A CA  1 
ATOM   3722 C C   . PRO   A 1 509 ? 64.200  120.945 112.934 1.00 133.91 ? 509 PRO   A C   1 
ATOM   3723 O O   . PRO   A 1 509 ? 64.590  119.772 112.958 1.00 133.91 ? 509 PRO   A O   1 
ATOM   3724 C CB  . PRO   A 1 509 ? 65.947  122.277 114.165 1.00 133.91 ? 509 PRO   A CB  1 
ATOM   3725 C CG  . PRO   A 1 509 ? 66.195  123.750 114.231 1.00 133.91 ? 509 PRO   A CG  1 
ATOM   3726 C CD  . PRO   A 1 509 ? 65.014  124.378 113.557 1.00 133.91 ? 509 PRO   A CD  1 
ATOM   3727 N N   . LYS   A 1 510 ? 62.911  121.261 113.040 1.00 135.05 ? 510 LYS   A N   1 
ATOM   3728 C CA  . LYS   A 1 510 ? 61.886  120.226 113.021 1.00 135.05 ? 510 LYS   A CA  1 
ATOM   3729 C C   . LYS   A 1 510 ? 61.512  119.790 111.610 1.00 135.05 ? 510 LYS   A C   1 
ATOM   3730 O O   . LYS   A 1 510 ? 60.858  118.754 111.453 1.00 135.05 ? 510 LYS   A O   1 
ATOM   3731 C CB  . LYS   A 1 510 ? 60.638  120.715 113.760 1.00 135.05 ? 510 LYS   A CB  1 
ATOM   3732 C CG  . LYS   A 1 510 ? 60.862  120.962 115.244 1.00 135.05 ? 510 LYS   A CG  1 
ATOM   3733 C CD  . LYS   A 1 510 ? 59.636  121.577 115.897 1.00 135.05 ? 510 LYS   A CD  1 
ATOM   3734 C CE  . LYS   A 1 510 ? 59.350  122.959 115.336 1.00 135.05 ? 510 LYS   A CE  1 
ATOM   3735 N NZ  . LYS   A 1 510 ? 58.187  123.601 116.009 1.00 135.05 ? 510 LYS   A NZ  1 
ATOM   3736 N N   . LEU   A 1 511 ? 61.913  120.548 110.588 1.00 131.38 ? 511 LEU   A N   1 
ATOM   3737 C CA  . LEU   A 1 511 ? 61.528  120.237 109.216 1.00 131.38 ? 511 LEU   A CA  1 
ATOM   3738 C C   . LEU   A 1 511 ? 62.345  119.091 108.631 1.00 131.38 ? 511 LEU   A C   1 
ATOM   3739 O O   . LEU   A 1 511 ? 61.870  118.411 107.714 1.00 131.38 ? 511 LEU   A O   1 
ATOM   3740 C CB  . LEU   A 1 511 ? 61.650  121.500 108.351 1.00 131.38 ? 511 LEU   A CB  1 
ATOM   3741 C CG  . LEU   A 1 511 ? 61.158  121.565 106.897 1.00 131.38 ? 511 LEU   A CG  1 
ATOM   3742 C CD1 . LEU   A 1 511 ? 60.791  122.997 106.557 1.00 131.38 ? 511 LEU   A CD1 1 
ATOM   3743 C CD2 . LEU   A 1 511 ? 62.201  121.076 105.900 1.00 131.38 ? 511 LEU   A CD2 1 
ATOM   3744 N N   . ASP   A 1 512 ? 63.554  118.859 109.140 1.00 126.31 ? 512 ASP   A N   1 
ATOM   3745 C CA  . ASP   A 1 512 ? 64.460  117.898 108.523 1.00 126.31 ? 512 ASP   A CA  1 
ATOM   3746 C C   . ASP   A 1 512 ? 63.931  116.470 108.621 1.00 126.31 ? 512 ASP   A C   1 
ATOM   3747 O O   . ASP   A 1 512 ? 63.213  116.105 109.556 1.00 126.31 ? 512 ASP   A O   1 
ATOM   3748 C CB  . ASP   A 1 512 ? 65.855  117.986 109.150 1.00 126.31 ? 512 ASP   A CB  1 
ATOM   3749 C CG  . ASP   A 1 512 ? 65.829  118.062 110.661 1.00 126.31 ? 512 ASP   A CG  1 
ATOM   3750 O OD1 . ASP   A 1 512 ? 65.111  117.272 111.308 1.00 126.31 ? 512 ASP   A OD1 1 
ATOM   3751 O OD2 . ASP   A 1 512 ? 66.564  118.912 111.204 1.00 126.31 ? 512 ASP   A OD2 1 
ATOM   3752 N N   . VAL   A 1 513 ? 64.285  115.666 107.621 1.00 119.04 ? 513 VAL   A N   1 
ATOM   3753 C CA  . VAL   A 1 513 ? 63.879  114.273 107.551 1.00 119.04 ? 513 VAL   A CA  1 
ATOM   3754 C C   . VAL   A 1 513 ? 65.043  113.334 107.843 1.00 119.04 ? 513 VAL   A C   1 
ATOM   3755 O O   . VAL   A 1 513 ? 64.899  112.385 108.617 1.00 119.04 ? 513 VAL   A O   1 
ATOM   3756 C CB  . VAL   A 1 513 ? 63.250  113.959 106.176 1.00 119.04 ? 513 VAL   A CB  1 
ATOM   3757 C CG1 . VAL   A 1 513 ? 62.800  112.506 106.109 1.00 119.04 ? 513 VAL   A CG1 1 
ATOM   3758 C CG2 . VAL   A 1 513 ? 62.089  114.900 105.895 1.00 119.04 ? 513 VAL   A CG2 1 
ATOM   3759 N N   . PHE   A 1 514 ? 66.207  113.587 107.246 1.00 109.12 ? 514 PHE   A N   1 
ATOM   3760 C CA  . PHE   A 1 514 ? 67.375  112.742 107.457 1.00 109.12 ? 514 PHE   A CA  1 
ATOM   3761 C C   . PHE   A 1 514 ? 68.257  113.212 108.605 1.00 109.12 ? 514 PHE   A C   1 
ATOM   3762 O O   . PHE   A 1 514 ? 69.193  112.492 108.972 1.00 109.12 ? 514 PHE   A O   1 
ATOM   3763 C CB  . PHE   A 1 514 ? 68.205  112.654 106.172 1.00 109.12 ? 514 PHE   A CB  1 
ATOM   3764 C CG  . PHE   A 1 514 ? 67.383  112.474 104.928 1.00 109.12 ? 514 PHE   A CG  1 
ATOM   3765 C CD1 . PHE   A 1 514 ? 66.465  111.441 104.831 1.00 109.12 ? 514 PHE   A CD1 1 
ATOM   3766 C CD2 . PHE   A 1 514 ? 67.535  113.328 103.852 1.00 109.12 ? 514 PHE   A CD2 1 
ATOM   3767 C CE1 . PHE   A 1 514 ? 65.709  111.272 103.687 1.00 109.12 ? 514 PHE   A CE1 1 
ATOM   3768 C CE2 . PHE   A 1 514 ? 66.782  113.166 102.706 1.00 109.12 ? 514 PHE   A CE2 1 
ATOM   3769 C CZ  . PHE   A 1 514 ? 65.868  112.136 102.624 1.00 109.12 ? 514 PHE   A CZ  1 
ATOM   3770 N N   . ASP   A 1 515 ? 67.980  114.393 109.170 1.00 120.02 ? 515 ASP   A N   1 
ATOM   3771 C CA  . ASP   A 1 515 ? 68.639  114.894 110.383 1.00 120.02 ? 515 ASP   A CA  1 
ATOM   3772 C C   . ASP   A 1 515 ? 70.156  114.993 110.208 1.00 120.02 ? 515 ASP   A C   1 
ATOM   3773 O O   . ASP   A 1 515 ? 70.928  114.716 111.128 1.00 120.02 ? 515 ASP   A O   1 
ATOM   3774 C CB  . ASP   A 1 515 ? 68.279  114.029 111.595 1.00 120.02 ? 515 ASP   A CB  1 
ATOM   3775 C CG  . ASP   A 1 515 ? 68.486  114.749 112.911 1.00 120.02 ? 515 ASP   A CG  1 
ATOM   3776 O OD1 . ASP   A 1 515 ? 68.068  115.921 113.019 1.00 120.02 ? 515 ASP   A OD1 1 
ATOM   3777 O OD2 . ASP   A 1 515 ? 69.066  114.144 113.837 1.00 120.02 ? 515 ASP   A OD2 1 
ATOM   3778 N N   . ALA   A 1 516 ? 70.589  115.383 109.008 1.00 116.54 ? 516 ALA   A N   1 
ATOM   3779 C CA  . ALA   A 1 516 ? 72.018  115.463 108.726 1.00 116.54 ? 516 ALA   A CA  1 
ATOM   3780 C C   . ALA   A 1 516 ? 72.665  116.676 109.387 1.00 116.54 ? 516 ALA   A C   1 
ATOM   3781 O O   . ALA   A 1 516 ? 73.777  116.576 109.916 1.00 116.54 ? 516 ALA   A O   1 
ATOM   3782 C CB  . ALA   A 1 516 ? 72.253  115.493 107.216 1.00 116.54 ? 516 ALA   A CB  1 
ATOM   3783 N N   . VAL   A 1 517 ? 71.991  117.828 109.356 1.00 117.70 ? 517 VAL   A N   1 
ATOM   3784 C CA  . VAL   A 1 517 ? 72.590  119.058 109.870 1.00 117.70 ? 517 VAL   A CA  1 
ATOM   3785 C C   . VAL   A 1 517 ? 72.683  119.025 111.392 1.00 117.70 ? 517 VAL   A C   1 
ATOM   3786 O O   . VAL   A 1 517 ? 73.715  119.391 111.970 1.00 117.70 ? 517 VAL   A O   1 
ATOM   3787 C CB  . VAL   A 1 517 ? 71.795  120.279 109.372 1.00 117.70 ? 517 VAL   A CB  1 
ATOM   3788 C CG1 . VAL   A 1 517 ? 72.137  121.518 110.187 1.00 117.70 ? 517 VAL   A CG1 1 
ATOM   3789 C CG2 . VAL   A 1 517 ? 72.067  120.518 107.895 1.00 117.70 ? 517 VAL   A CG2 1 
ATOM   3790 N N   . VAL   A 1 518 ? 71.616  118.583 112.063 1.00 121.72 ? 518 VAL   A N   1 
ATOM   3791 C CA  . VAL   A 1 518 ? 71.570  118.628 113.524 1.00 121.72 ? 518 VAL   A CA  1 
ATOM   3792 C C   . VAL   A 1 518 ? 72.609  117.692 114.133 1.00 121.72 ? 518 VAL   A C   1 
ATOM   3793 O O   . VAL   A 1 518 ? 73.281  118.042 115.110 1.00 121.72 ? 518 VAL   A O   1 
ATOM   3794 C CB  . VAL   A 1 518 ? 70.151  118.300 114.023 1.00 121.72 ? 518 VAL   A CB  1 
ATOM   3795 C CG1 . VAL   A 1 518 ? 70.033  118.582 115.512 1.00 121.72 ? 518 VAL   A CG1 1 
ATOM   3796 C CG2 . VAL   A 1 518 ? 69.123  119.102 113.246 1.00 121.72 ? 518 VAL   A CG2 1 
ATOM   3797 N N   . ALA   A 1 519 ? 72.757  116.496 113.573 1.00 120.08 ? 519 ALA   A N   1 
ATOM   3798 C CA  . ALA   A 1 519 ? 73.737  115.539 114.076 1.00 120.08 ? 519 ALA   A CA  1 
ATOM   3799 C C   . ALA   A 1 519 ? 75.147  115.924 113.640 1.00 120.08 ? 519 ALA   A C   1 
ATOM   3800 O O   . ALA   A 1 519 ? 75.770  116.809 114.227 1.00 120.08 ? 519 ALA   A O   1 
ATOM   3801 C CB  . ALA   A 1 519 ? 73.399  114.135 113.603 1.00 120.08 ? 519 ALA   A CB  1 
HETATM 3802 C C10 . A1AOW B 2 .   ? 80.744  97.445  76.323  1.00 56.21  ? 801 A1AOW A C10 1 
HETATM 3803 C C13 . A1AOW B 2 .   ? 81.557  100.159 75.215  1.00 56.21  ? 801 A1AOW A C13 1 
HETATM 3804 C C15 . A1AOW B 2 .   ? 80.005  94.070  74.281  1.00 56.21  ? 801 A1AOW A C15 1 
HETATM 3805 C C17 . A1AOW B 2 .   ? 79.670  92.889  73.400  1.00 56.21  ? 801 A1AOW A C17 1 
HETATM 3806 C C20 . A1AOW B 2 .   ? 73.945  92.224  77.354  1.00 56.21  ? 801 A1AOW A C20 1 
HETATM 3807 C C21 . A1AOW B 2 .   ? 78.178  92.606  73.200  1.00 56.21  ? 801 A1AOW A C21 1 
HETATM 3808 C C22 . A1AOW B 2 .   ? 74.400  91.441  76.125  1.00 56.21  ? 801 A1AOW A C22 1 
HETATM 3809 C C24 . A1AOW B 2 .   ? 75.372  90.956  74.193  1.00 56.21  ? 801 A1AOW A C24 1 
HETATM 3810 C C26 . A1AOW B 2 .   ? 72.784  91.515  78.037  1.00 56.21  ? 801 A1AOW A C26 1 
HETATM 3811 C C28 . A1AOW B 2 .   ? 84.395  95.208  73.774  1.00 56.21  ? 801 A1AOW A C28 1 
HETATM 3812 C C08 . A1AOW B 2 .   ? 80.727  96.651  75.133  1.00 56.21  ? 801 A1AOW A C08 1 
HETATM 3813 C C09 . A1AOW B 2 .   ? 81.186  97.399  73.967  1.00 56.21  ? 801 A1AOW A C09 1 
HETATM 3814 C C11 . A1AOW B 2 .   ? 80.552  98.775  73.823  1.00 56.21  ? 801 A1AOW A C11 1 
HETATM 3815 C C12 . A1AOW B 2 .   ? 80.083  98.812  76.169  1.00 56.21  ? 801 A1AOW A C12 1 
HETATM 3816 C C14 . A1AOW B 2 .   ? 81.437  94.448  74.554  1.00 56.21  ? 801 A1AOW A C14 1 
HETATM 3817 C C16 . A1AOW B 2 .   ? 82.569  93.652  73.947  1.00 56.21  ? 801 A1AOW A C16 1 
HETATM 3818 C C18 . A1AOW B 2 .   ? 82.256  92.457  73.067  1.00 56.21  ? 801 A1AOW A C18 1 
HETATM 3819 C C19 . A1AOW B 2 .   ? 80.805  92.072  72.787  1.00 56.21  ? 801 A1AOW A C19 1 
HETATM 3820 C C23 . A1AOW B 2 .   ? 76.180  91.079  72.899  1.00 56.21  ? 801 A1AOW A C23 1 
HETATM 3821 C C25 . A1AOW B 2 .   ? 75.169  91.928  75.110  1.00 56.21  ? 801 A1AOW A C25 1 
HETATM 3822 C C27 . A1AOW B 2 .   ? 75.091  92.299  78.348  1.00 56.21  ? 801 A1AOW A C27 1 
HETATM 3823 N N05 . A1AOW B 2 .   ? 80.537  99.562  75.020  1.00 56.21  ? 801 A1AOW A N05 1 
HETATM 3824 N N06 . A1AOW B 2 .   ? 77.607  91.273  73.081  1.00 56.21  ? 801 A1AOW A N06 1 
HETATM 3825 N N07 . A1AOW B 2 .   ? 74.125  90.179  75.841  1.00 56.21  ? 801 A1AOW A N07 1 
HETATM 3826 O O01 . A1AOW B 2 .   ? 81.682  95.539  75.369  1.00 56.21  ? 801 A1AOW A O01 1 
HETATM 3827 O O02 . A1AOW B 2 .   ? 83.908  93.961  74.188  1.00 56.21  ? 801 A1AOW A O02 1 
HETATM 3828 O O03 . A1AOW B 2 .   ? 74.730  89.876  74.641  1.00 56.21  ? 801 A1AOW A O03 1 
HETATM 3829 O O04 . A1AOW B 2 .   ? 77.457  93.529  73.150  1.00 56.21  ? 801 A1AOW A O04 1 
# 
