data_9BD5
# 
_entry.id   9BD5 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.399 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BD5         pdb_00009bd5 10.2210/pdb9bd5/pdb 
WWPDB D_1000283097 ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-20 
2 'Structure model' 1 1 2024-12-18 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_audit_revision_group.ordinal             1 
_pdbx_audit_revision_group.revision_ordinal    2 
_pdbx_audit_revision_group.data_content_type   'Structure model' 
_pdbx_audit_revision_group.group               'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 2 'Structure model' '_citation.journal_volume'          
2 2 'Structure model' '_citation.page_first'              
3 2 'Structure model' '_citation.page_last'               
4 2 'Structure model' '_citation.pdbx_database_id_PubMed' 
5 2 'Structure model' '_citation.title'                   
6 2 'Structure model' '_citation_author.name'             
# 
loop_
_database_PDB_caveat.id 
_database_PDB_caveat.text 
1 
;Residues PRO A 327 and THR A 328 are linked together in the model; however, there are residues between them in the deposited polymeric sequence.
;
2 
;Residues PRO B 327 and THR B 328 are linked together in the model; however, there are residues between them in the deposited polymeric sequence.
;
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BD5 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-11 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           Y 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              thosmith@utmb.edu 
_pdbx_contact_author.name_first         Thomas 
_pdbx_contact_author.name_last          Smith 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-0978-1494 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Habib, M.H.' 1 ?                   
'Smith, T.J.' 2 0000-0002-0978-1494 
# 
loop_
_citation.abstract 
_citation.abstract_id_CAS 
_citation.book_id_ISBN 
_citation.book_publisher 
_citation.book_publisher_city 
_citation.book_title 
_citation.coordinate_linkage 
_citation.country 
_citation.database_id_Medline 
_citation.details 
_citation.id 
_citation.journal_abbrev 
_citation.journal_id_ASTM 
_citation.journal_id_CSD 
_citation.journal_id_ISSN 
_citation.journal_full 
_citation.journal_issue 
_citation.journal_volume 
_citation.language 
_citation.page_first 
_citation.page_last 
_citation.title 
_citation.year 
_citation.database_id_CSD 
_citation.pdbx_database_id_DOI 
_citation.pdbx_database_id_PubMed 
_citation.pdbx_database_id_patent 
_citation.unpublished_flag 
? ? ? ? ? ? ? CH ? ? primary 'Front Microbiol'                                ?      ?    1664-302X ? ? 15 ? 1501112 1501112 
;Polymerization potential of a bacterial CotA-laccase for beta-naphthol: enzyme structure and comprehensive polymer characterization.
;
2024 ? 10.3389/fmicb.2024.1501112 39640860 ? ? 
? ? ? ? ? ? ? DK ? ? 1       'Acta Crystallogr., Sect. D: Biol. Crystallogr.' ABCRE6 0766 0907-4449 ? ? 75 ? 861     877     
'Macromolecular structure determination using X-rays, neutrons and electrons: recent developments in Phenix' 2019 ? 
10.1107/S2059798319011471  31588918 ? ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Refaat, M.'             1  ?                   
primary 'ElRakaiby, M.T.'        2  ?                   
primary 'El Hariri El Nokab, M.' 3  ?                   
primary 'Es Sayed, J.'           4  ?                   
primary 'Elshewy, A.'            5  ?                   
primary 'Sebakhy, K.O.'          6  ?                   
primary 'Moneib, N.'             7  ?                   
primary 'Wang, T.'               8  ?                   
primary 'Smith, T.J.'            9  ?                   
primary 'Habib, M.H.'            10 ?                   
1       'Liebschner, D.'         11 0000-0003-3921-3209 
1       'Afonine, P.V.'          12 0000-0002-5052-991X 
1       'Baker, M.L.'            13 ?                   
1       'Bunkoczi, G.'           14 ?                   
1       'Chen, V.B.'             15 0000-0003-2492-979X 
1       'Croll, T.I.'            16 ?                   
1       'Hintze, B.'             17 0000-0002-4871-2096 
1       'Hung, L.W.'             18 0000-0001-6690-8458 
1       'Jain, S.'               19 ?                   
1       'McCoy, A.J.'            20 ?                   
1       'Moriarty, N.W.'         21 0000-0001-8857-9464 
1       'Oeffner, R.D.'          22 0000-0003-3107-2202 
1       'Poon, B.K.'             23 0000-0001-9633-6067 
1       'Prisant, M.G.'          24 ?                   
1       'Read, R.J.'             25 0000-0001-8273-0047 
1       'Richardson, J.S.'       26 0000-0002-3311-2944 
1       'Richardson, D.C.'       27 ?                   
1       'Sammito, M.D.'          28 0000-0002-8346-9247 
1       'Sobolev, O.V.'          29 0000-0002-0623-3214 
1       'Stockwell, D.H.'        30 ?                   
1       'Terwilliger, T.C.'      31 0000-0001-6384-0320 
1       'Urzhumtsev, A.G.'       32 ?                   
1       'Videau, L.L.'           33 ?                   
1       'Williams, C.J.'         34 ?                   
1       'Adams, P.D.'            35 0000-0001-9333-8219 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man 'Spore coat protein A' 61477.648 2   ? ? ? ? 
2 non-polymer syn 'SULFATE ION'          96.063    23  ? ? ? ? 
3 non-polymer syn 'COPPER (II) ION'      63.546    8   ? ? ? ? 
4 water       nat water                  18.015    555 ? ? ? ? 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MKLEKFVDKLPIPKVLKPHSKSKEMTYYEVTMKEFQQQLHRDLPPTRLFGYNGVYPGPTFEVQKHEKVAVKWLNKLPDHH
FLPVDHTIHDDGHHEHEVKTVVHLHGGRTPPDSDGYPEAWYTKDFQVKGPFFEREVYEYPNEQDATALWYHDHAMAITRL
NVYAGLVGLYFIRDREERSLNLPKGEYEIPLLIQDKSFHEDGSLFYPRQPDNPSPDLPDPSIVPAFCGDTILVNGKVWPY
DELEPRKYRFRILNASNTRIFELYFDHDITFHQIGTDGGLLQHPVKVNELVIAPAERCDIIVDFSRAEGKTVTLKNRIGC
SGQDADPDTDANIMQFRISKPLKQKDTSSLPRILRKRPFYRRHKINTLRNLSLGASLDQYGRPVLLLNNTKWHEPVTETP
ALGSTEIWSIINAGRAIHPIHLHLVQFLILDHRPFDIERYQENGELVFTGPAAPPAQNEKGLKDTVKVPPGSVTRIIATF
APYSGRYVWHCHILEHEDYDMMRPLEVTDIRHQEFEAWARTKTHLRRGSE
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MKLEKFVDKLPIPKVLKPHSKSKEMTYYEVTMKEFQQQLHRDLPPTRLFGYNGVYPGPTFEVQKHEKVAVKWLNKLPDHH
FLPVDHTIHDDGHHEHEVKTVVHLHGGRTPPDSDGYPEAWYTKDFQVKGPFFEREVYEYPNEQDATALWYHDHAMAITRL
NVYAGLVGLYFIRDREERSLNLPKGEYEIPLLIQDKSFHEDGSLFYPRQPDNPSPDLPDPSIVPAFCGDTILVNGKVWPY
DELEPRKYRFRILNASNTRIFELYFDHDITFHQIGTDGGLLQHPVKVNELVIAPAERCDIIVDFSRAEGKTVTLKNRIGC
SGQDADPDTDANIMQFRISKPLKQKDTSSLPRILRKRPFYRRHKINTLRNLSLGASLDQYGRPVLLLNNTKWHEPVTETP
ALGSTEIWSIINAGRAIHPIHLHLVQFLILDHRPFDIERYQENGELVFTGPAAPPAQNEKGLKDTVKVPPGSVTRIIATF
APYSGRYVWHCHILEHEDYDMMRPLEVTDIRHQEFEAWARTKTHLRRGSE
;
_entity_poly.pdbx_strand_id                 A,B 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_pdbx_entity_nonpoly.entity_id 
_pdbx_entity_nonpoly.name 
_pdbx_entity_nonpoly.comp_id 
2 'SULFATE ION'     SO4 
3 'COPPER (II) ION' CU  
4 water             HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   MET n 
1 2   LYS n 
1 3   LEU n 
1 4   GLU n 
1 5   LYS n 
1 6   PHE n 
1 7   VAL n 
1 8   ASP n 
1 9   LYS n 
1 10  LEU n 
1 11  PRO n 
1 12  ILE n 
1 13  PRO n 
1 14  LYS n 
1 15  VAL n 
1 16  LEU n 
1 17  LYS n 
1 18  PRO n 
1 19  HIS n 
1 20  SER n 
1 21  LYS n 
1 22  SER n 
1 23  LYS n 
1 24  GLU n 
1 25  MET n 
1 26  THR n 
1 27  TYR n 
1 28  TYR n 
1 29  GLU n 
1 30  VAL n 
1 31  THR n 
1 32  MET n 
1 33  LYS n 
1 34  GLU n 
1 35  PHE n 
1 36  GLN n 
1 37  GLN n 
1 38  GLN n 
1 39  LEU n 
1 40  HIS n 
1 41  ARG n 
1 42  ASP n 
1 43  LEU n 
1 44  PRO n 
1 45  PRO n 
1 46  THR n 
1 47  ARG n 
1 48  LEU n 
1 49  PHE n 
1 50  GLY n 
1 51  TYR n 
1 52  ASN n 
1 53  GLY n 
1 54  VAL n 
1 55  TYR n 
1 56  PRO n 
1 57  GLY n 
1 58  PRO n 
1 59  THR n 
1 60  PHE n 
1 61  GLU n 
1 62  VAL n 
1 63  GLN n 
1 64  LYS n 
1 65  HIS n 
1 66  GLU n 
1 67  LYS n 
1 68  VAL n 
1 69  ALA n 
1 70  VAL n 
1 71  LYS n 
1 72  TRP n 
1 73  LEU n 
1 74  ASN n 
1 75  LYS n 
1 76  LEU n 
1 77  PRO n 
1 78  ASP n 
1 79  HIS n 
1 80  HIS n 
1 81  PHE n 
1 82  LEU n 
1 83  PRO n 
1 84  VAL n 
1 85  ASP n 
1 86  HIS n 
1 87  THR n 
1 88  ILE n 
1 89  HIS n 
1 90  ASP n 
1 91  ASP n 
1 92  GLY n 
1 93  HIS n 
1 94  HIS n 
1 95  GLU n 
1 96  HIS n 
1 97  GLU n 
1 98  VAL n 
1 99  LYS n 
1 100 THR n 
1 101 VAL n 
1 102 VAL n 
1 103 HIS n 
1 104 LEU n 
1 105 HIS n 
1 106 GLY n 
1 107 GLY n 
1 108 ARG n 
1 109 THR n 
1 110 PRO n 
1 111 PRO n 
1 112 ASP n 
1 113 SER n 
1 114 ASP n 
1 115 GLY n 
1 116 TYR n 
1 117 PRO n 
1 118 GLU n 
1 119 ALA n 
1 120 TRP n 
1 121 TYR n 
1 122 THR n 
1 123 LYS n 
1 124 ASP n 
1 125 PHE n 
1 126 GLN n 
1 127 VAL n 
1 128 LYS n 
1 129 GLY n 
1 130 PRO n 
1 131 PHE n 
1 132 PHE n 
1 133 GLU n 
1 134 ARG n 
1 135 GLU n 
1 136 VAL n 
1 137 TYR n 
1 138 GLU n 
1 139 TYR n 
1 140 PRO n 
1 141 ASN n 
1 142 GLU n 
1 143 GLN n 
1 144 ASP n 
1 145 ALA n 
1 146 THR n 
1 147 ALA n 
1 148 LEU n 
1 149 TRP n 
1 150 TYR n 
1 151 HIS n 
1 152 ASP n 
1 153 HIS n 
1 154 ALA n 
1 155 MET n 
1 156 ALA n 
1 157 ILE n 
1 158 THR n 
1 159 ARG n 
1 160 LEU n 
1 161 ASN n 
1 162 VAL n 
1 163 TYR n 
1 164 ALA n 
1 165 GLY n 
1 166 LEU n 
1 167 VAL n 
1 168 GLY n 
1 169 LEU n 
1 170 TYR n 
1 171 PHE n 
1 172 ILE n 
1 173 ARG n 
1 174 ASP n 
1 175 ARG n 
1 176 GLU n 
1 177 GLU n 
1 178 ARG n 
1 179 SER n 
1 180 LEU n 
1 181 ASN n 
1 182 LEU n 
1 183 PRO n 
1 184 LYS n 
1 185 GLY n 
1 186 GLU n 
1 187 TYR n 
1 188 GLU n 
1 189 ILE n 
1 190 PRO n 
1 191 LEU n 
1 192 LEU n 
1 193 ILE n 
1 194 GLN n 
1 195 ASP n 
1 196 LYS n 
1 197 SER n 
1 198 PHE n 
1 199 HIS n 
1 200 GLU n 
1 201 ASP n 
1 202 GLY n 
1 203 SER n 
1 204 LEU n 
1 205 PHE n 
1 206 TYR n 
1 207 PRO n 
1 208 ARG n 
1 209 GLN n 
1 210 PRO n 
1 211 ASP n 
1 212 ASN n 
1 213 PRO n 
1 214 SER n 
1 215 PRO n 
1 216 ASP n 
1 217 LEU n 
1 218 PRO n 
1 219 ASP n 
1 220 PRO n 
1 221 SER n 
1 222 ILE n 
1 223 VAL n 
1 224 PRO n 
1 225 ALA n 
1 226 PHE n 
1 227 CYS n 
1 228 GLY n 
1 229 ASP n 
1 230 THR n 
1 231 ILE n 
1 232 LEU n 
1 233 VAL n 
1 234 ASN n 
1 235 GLY n 
1 236 LYS n 
1 237 VAL n 
1 238 TRP n 
1 239 PRO n 
1 240 TYR n 
1 241 ASP n 
1 242 GLU n 
1 243 LEU n 
1 244 GLU n 
1 245 PRO n 
1 246 ARG n 
1 247 LYS n 
1 248 TYR n 
1 249 ARG n 
1 250 PHE n 
1 251 ARG n 
1 252 ILE n 
1 253 LEU n 
1 254 ASN n 
1 255 ALA n 
1 256 SER n 
1 257 ASN n 
1 258 THR n 
1 259 ARG n 
1 260 ILE n 
1 261 PHE n 
1 262 GLU n 
1 263 LEU n 
1 264 TYR n 
1 265 PHE n 
1 266 ASP n 
1 267 HIS n 
1 268 ASP n 
1 269 ILE n 
1 270 THR n 
1 271 PHE n 
1 272 HIS n 
1 273 GLN n 
1 274 ILE n 
1 275 GLY n 
1 276 THR n 
1 277 ASP n 
1 278 GLY n 
1 279 GLY n 
1 280 LEU n 
1 281 LEU n 
1 282 GLN n 
1 283 HIS n 
1 284 PRO n 
1 285 VAL n 
1 286 LYS n 
1 287 VAL n 
1 288 ASN n 
1 289 GLU n 
1 290 LEU n 
1 291 VAL n 
1 292 ILE n 
1 293 ALA n 
1 294 PRO n 
1 295 ALA n 
1 296 GLU n 
1 297 ARG n 
1 298 CYS n 
1 299 ASP n 
1 300 ILE n 
1 301 ILE n 
1 302 VAL n 
1 303 ASP n 
1 304 PHE n 
1 305 SER n 
1 306 ARG n 
1 307 ALA n 
1 308 GLU n 
1 309 GLY n 
1 310 LYS n 
1 311 THR n 
1 312 VAL n 
1 313 THR n 
1 314 LEU n 
1 315 LYS n 
1 316 ASN n 
1 317 ARG n 
1 318 ILE n 
1 319 GLY n 
1 320 CYS n 
1 321 SER n 
1 322 GLY n 
1 323 GLN n 
1 324 ASP n 
1 325 ALA n 
1 326 ASP n 
1 327 PRO n 
1 328 ASP n 
1 329 THR n 
1 330 ASP n 
1 331 ALA n 
1 332 ASN n 
1 333 ILE n 
1 334 MET n 
1 335 GLN n 
1 336 PHE n 
1 337 ARG n 
1 338 ILE n 
1 339 SER n 
1 340 LYS n 
1 341 PRO n 
1 342 LEU n 
1 343 LYS n 
1 344 GLN n 
1 345 LYS n 
1 346 ASP n 
1 347 THR n 
1 348 SER n 
1 349 SER n 
1 350 LEU n 
1 351 PRO n 
1 352 ARG n 
1 353 ILE n 
1 354 LEU n 
1 355 ARG n 
1 356 LYS n 
1 357 ARG n 
1 358 PRO n 
1 359 PHE n 
1 360 TYR n 
1 361 ARG n 
1 362 ARG n 
1 363 HIS n 
1 364 LYS n 
1 365 ILE n 
1 366 ASN n 
1 367 THR n 
1 368 LEU n 
1 369 ARG n 
1 370 ASN n 
1 371 LEU n 
1 372 SER n 
1 373 LEU n 
1 374 GLY n 
1 375 ALA n 
1 376 SER n 
1 377 LEU n 
1 378 ASP n 
1 379 GLN n 
1 380 TYR n 
1 381 GLY n 
1 382 ARG n 
1 383 PRO n 
1 384 VAL n 
1 385 LEU n 
1 386 LEU n 
1 387 LEU n 
1 388 ASN n 
1 389 ASN n 
1 390 THR n 
1 391 LYS n 
1 392 TRP n 
1 393 HIS n 
1 394 GLU n 
1 395 PRO n 
1 396 VAL n 
1 397 THR n 
1 398 GLU n 
1 399 THR n 
1 400 PRO n 
1 401 ALA n 
1 402 LEU n 
1 403 GLY n 
1 404 SER n 
1 405 THR n 
1 406 GLU n 
1 407 ILE n 
1 408 TRP n 
1 409 SER n 
1 410 ILE n 
1 411 ILE n 
1 412 ASN n 
1 413 ALA n 
1 414 GLY n 
1 415 ARG n 
1 416 ALA n 
1 417 ILE n 
1 418 HIS n 
1 419 PRO n 
1 420 ILE n 
1 421 HIS n 
1 422 LEU n 
1 423 HIS n 
1 424 LEU n 
1 425 VAL n 
1 426 GLN n 
1 427 PHE n 
1 428 LEU n 
1 429 ILE n 
1 430 LEU n 
1 431 ASP n 
1 432 HIS n 
1 433 ARG n 
1 434 PRO n 
1 435 PHE n 
1 436 ASP n 
1 437 ILE n 
1 438 GLU n 
1 439 ARG n 
1 440 TYR n 
1 441 GLN n 
1 442 GLU n 
1 443 ASN n 
1 444 GLY n 
1 445 GLU n 
1 446 LEU n 
1 447 VAL n 
1 448 PHE n 
1 449 THR n 
1 450 GLY n 
1 451 PRO n 
1 452 ALA n 
1 453 ALA n 
1 454 PRO n 
1 455 PRO n 
1 456 ALA n 
1 457 GLN n 
1 458 ASN n 
1 459 GLU n 
1 460 LYS n 
1 461 GLY n 
1 462 LEU n 
1 463 LYS n 
1 464 ASP n 
1 465 THR n 
1 466 VAL n 
1 467 LYS n 
1 468 VAL n 
1 469 PRO n 
1 470 PRO n 
1 471 GLY n 
1 472 SER n 
1 473 VAL n 
1 474 THR n 
1 475 ARG n 
1 476 ILE n 
1 477 ILE n 
1 478 ALA n 
1 479 THR n 
1 480 PHE n 
1 481 ALA n 
1 482 PRO n 
1 483 TYR n 
1 484 SER n 
1 485 GLY n 
1 486 ARG n 
1 487 TYR n 
1 488 VAL n 
1 489 TRP n 
1 490 HIS n 
1 491 CYS n 
1 492 HIS n 
1 493 ILE n 
1 494 LEU n 
1 495 GLU n 
1 496 HIS n 
1 497 GLU n 
1 498 ASP n 
1 499 TYR n 
1 500 ASP n 
1 501 MET n 
1 502 MET n 
1 503 ARG n 
1 504 PRO n 
1 505 LEU n 
1 506 GLU n 
1 507 VAL n 
1 508 THR n 
1 509 ASP n 
1 510 ILE n 
1 511 ARG n 
1 512 HIS n 
1 513 GLN n 
1 514 GLU n 
1 515 PHE n 
1 516 GLU n 
1 517 ALA n 
1 518 TRP n 
1 519 ALA n 
1 520 ARG n 
1 521 THR n 
1 522 LYS n 
1 523 THR n 
1 524 HIS n 
1 525 LEU n 
1 526 ARG n 
1 527 ARG n 
1 528 GLY n 
1 529 SER n 
1 530 GLU n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   530 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 B4121_2419 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Bacillus paralicheniformis ATCC 9945a' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     766760 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking' y ALANINE           ? 'C3 H7 N O2'     89.093  
ARG 'L-peptide linking' y ARGININE          ? 'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking' y ASPARAGINE        ? 'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking' y 'ASPARTIC ACID'   ? 'C4 H7 N O4'     133.103 
CU  non-polymer         . 'COPPER (II) ION' ? 'Cu 2'           63.546  
CYS 'L-peptide linking' y CYSTEINE          ? 'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking' y GLUTAMINE         ? 'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking' y 'GLUTAMIC ACID'   ? 'C5 H9 N O4'     147.129 
GLY 'peptide linking'   y GLYCINE           ? 'C2 H5 N O2'     75.067  
HIS 'L-peptide linking' y HISTIDINE         ? 'C6 H10 N3 O2 1' 156.162 
HOH non-polymer         . WATER             ? 'H2 O'           18.015  
ILE 'L-peptide linking' y ISOLEUCINE        ? 'C6 H13 N O2'    131.173 
LEU 'L-peptide linking' y LEUCINE           ? 'C6 H13 N O2'    131.173 
LYS 'L-peptide linking' y LYSINE            ? 'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking' y METHIONINE        ? 'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking' y PHENYLALANINE     ? 'C9 H11 N O2'    165.189 
PRO 'L-peptide linking' y PROLINE           ? 'C5 H9 N O2'     115.130 
SER 'L-peptide linking' y SERINE            ? 'C3 H7 N O3'     105.093 
SO4 non-polymer         . 'SULFATE ION'     ? 'O4 S -2'        96.063  
THR 'L-peptide linking' y THREONINE         ? 'C4 H9 N O3'     119.119 
TRP 'L-peptide linking' y TRYPTOPHAN        ? 'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking' y TYROSINE          ? 'C9 H11 N O3'    181.189 
VAL 'L-peptide linking' y VALINE            ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   MET 1   1   ?   ?   ?   A . n 
A 1 2   LYS 2   2   2   LYS LYS A . n 
A 1 3   LEU 3   3   3   LEU LEU A . n 
A 1 4   GLU 4   4   4   GLU GLU A . n 
A 1 5   LYS 5   5   5   LYS LYS A . n 
A 1 6   PHE 6   6   6   PHE PHE A . n 
A 1 7   VAL 7   7   7   VAL VAL A . n 
A 1 8   ASP 8   8   8   ASP ASP A . n 
A 1 9   LYS 9   9   9   LYS LYS A . n 
A 1 10  LEU 10  10  10  LEU LEU A . n 
A 1 11  PRO 11  11  11  PRO PRO A . n 
A 1 12  ILE 12  12  12  ILE ILE A . n 
A 1 13  PRO 13  13  13  PRO PRO A . n 
A 1 14  LYS 14  14  14  LYS LYS A . n 
A 1 15  VAL 15  15  15  VAL VAL A . n 
A 1 16  LEU 16  16  16  LEU LEU A . n 
A 1 17  LYS 17  17  17  LYS LYS A . n 
A 1 18  PRO 18  18  18  PRO PRO A . n 
A 1 19  HIS 19  19  19  HIS HIS A . n 
A 1 20  SER 20  20  20  SER SER A . n 
A 1 21  LYS 21  21  21  LYS LYS A . n 
A 1 22  SER 22  22  22  SER SER A . n 
A 1 23  LYS 23  23  23  LYS LYS A . n 
A 1 24  GLU 24  24  24  GLU GLU A . n 
A 1 25  MET 25  25  25  MET MET A . n 
A 1 26  THR 26  26  26  THR THR A . n 
A 1 27  TYR 27  27  27  TYR TYR A . n 
A 1 28  TYR 28  28  28  TYR TYR A . n 
A 1 29  GLU 29  29  29  GLU GLU A . n 
A 1 30  VAL 30  30  30  VAL VAL A . n 
A 1 31  THR 31  31  31  THR THR A . n 
A 1 32  MET 32  32  32  MET MET A . n 
A 1 33  LYS 33  33  33  LYS LYS A . n 
A 1 34  GLU 34  34  34  GLU GLU A . n 
A 1 35  PHE 35  35  35  PHE PHE A . n 
A 1 36  GLN 36  36  36  GLN GLN A . n 
A 1 37  GLN 37  37  37  GLN GLN A . n 
A 1 38  GLN 38  38  38  GLN GLN A . n 
A 1 39  LEU 39  39  39  LEU LEU A . n 
A 1 40  HIS 40  40  40  HIS HIS A . n 
A 1 41  ARG 41  41  41  ARG ARG A . n 
A 1 42  ASP 42  42  42  ASP ASP A . n 
A 1 43  LEU 43  43  43  LEU LEU A . n 
A 1 44  PRO 44  44  44  PRO PRO A . n 
A 1 45  PRO 45  45  45  PRO PRO A . n 
A 1 46  THR 46  46  46  THR THR A . n 
A 1 47  ARG 47  47  47  ARG ARG A . n 
A 1 48  LEU 48  48  48  LEU LEU A . n 
A 1 49  PHE 49  49  49  PHE PHE A . n 
A 1 50  GLY 50  50  50  GLY GLY A . n 
A 1 51  TYR 51  51  51  TYR TYR A . n 
A 1 52  ASN 52  52  52  ASN ASN A . n 
A 1 53  GLY 53  53  53  GLY GLY A . n 
A 1 54  VAL 54  54  54  VAL VAL A . n 
A 1 55  TYR 55  55  55  TYR TYR A . n 
A 1 56  PRO 56  56  56  PRO PRO A . n 
A 1 57  GLY 57  57  57  GLY GLY A . n 
A 1 58  PRO 58  58  58  PRO PRO A . n 
A 1 59  THR 59  59  59  THR THR A . n 
A 1 60  PHE 60  60  60  PHE PHE A . n 
A 1 61  GLU 61  61  61  GLU GLU A . n 
A 1 62  VAL 62  62  62  VAL VAL A . n 
A 1 63  GLN 63  63  63  GLN GLN A . n 
A 1 64  LYS 64  64  64  LYS LYS A . n 
A 1 65  HIS 65  65  65  HIS HIS A . n 
A 1 66  GLU 66  66  66  GLU GLU A . n 
A 1 67  LYS 67  67  67  LYS LYS A . n 
A 1 68  VAL 68  68  68  VAL VAL A . n 
A 1 69  ALA 69  69  69  ALA ALA A . n 
A 1 70  VAL 70  70  70  VAL VAL A . n 
A 1 71  LYS 71  71  71  LYS LYS A . n 
A 1 72  TRP 72  72  72  TRP TRP A . n 
A 1 73  LEU 73  73  73  LEU LEU A . n 
A 1 74  ASN 74  74  74  ASN ASN A . n 
A 1 75  LYS 75  75  75  LYS LYS A . n 
A 1 76  LEU 76  76  76  LEU LEU A . n 
A 1 77  PRO 77  77  77  PRO PRO A . n 
A 1 78  ASP 78  78  78  ASP ASP A . n 
A 1 79  HIS 79  79  79  HIS HIS A . n 
A 1 80  HIS 80  80  80  HIS HIS A . n 
A 1 81  PHE 81  81  81  PHE PHE A . n 
A 1 82  LEU 82  82  82  LEU LEU A . n 
A 1 83  PRO 83  83  83  PRO PRO A . n 
A 1 84  VAL 84  84  84  VAL VAL A . n 
A 1 85  ASP 85  85  85  ASP ASP A . n 
A 1 86  HIS 86  86  86  HIS HIS A . n 
A 1 87  THR 87  87  87  THR THR A . n 
A 1 88  ILE 88  88  88  ILE ILE A . n 
A 1 89  HIS 89  89  89  HIS HIS A . n 
A 1 90  ASP 90  90  ?   ?   ?   A . n 
A 1 91  ASP 91  91  ?   ?   ?   A . n 
A 1 92  GLY 92  92  ?   ?   ?   A . n 
A 1 93  HIS 93  93  ?   ?   ?   A . n 
A 1 94  HIS 94  94  ?   ?   ?   A . n 
A 1 95  GLU 95  95  ?   ?   ?   A . n 
A 1 96  HIS 96  96  ?   ?   ?   A . n 
A 1 97  GLU 97  97  97  GLU GLU A . n 
A 1 98  VAL 98  98  98  VAL VAL A . n 
A 1 99  LYS 99  99  99  LYS LYS A . n 
A 1 100 THR 100 100 100 THR THR A . n 
A 1 101 VAL 101 101 101 VAL VAL A . n 
A 1 102 VAL 102 102 102 VAL VAL A . n 
A 1 103 HIS 103 103 103 HIS HIS A . n 
A 1 104 LEU 104 104 104 LEU LEU A . n 
A 1 105 HIS 105 105 105 HIS HIS A . n 
A 1 106 GLY 106 106 106 GLY GLY A . n 
A 1 107 GLY 107 107 107 GLY GLY A . n 
A 1 108 ARG 108 108 108 ARG ARG A . n 
A 1 109 THR 109 109 109 THR THR A . n 
A 1 110 PRO 110 110 110 PRO PRO A . n 
A 1 111 PRO 111 111 111 PRO PRO A . n 
A 1 112 ASP 112 112 112 ASP ASP A . n 
A 1 113 SER 113 113 113 SER SER A . n 
A 1 114 ASP 114 114 114 ASP ASP A . n 
A 1 115 GLY 115 115 115 GLY GLY A . n 
A 1 116 TYR 116 116 116 TYR TYR A . n 
A 1 117 PRO 117 117 117 PRO PRO A . n 
A 1 118 GLU 118 118 118 GLU GLU A . n 
A 1 119 ALA 119 119 119 ALA ALA A . n 
A 1 120 TRP 120 120 120 TRP TRP A . n 
A 1 121 TYR 121 121 121 TYR TYR A . n 
A 1 122 THR 122 122 122 THR THR A . n 
A 1 123 LYS 123 123 123 LYS LYS A . n 
A 1 124 ASP 124 124 124 ASP ASP A . n 
A 1 125 PHE 125 125 125 PHE PHE A . n 
A 1 126 GLN 126 126 126 GLN GLN A . n 
A 1 127 VAL 127 127 127 VAL VAL A . n 
A 1 128 LYS 128 128 128 LYS LYS A . n 
A 1 129 GLY 129 129 129 GLY GLY A . n 
A 1 130 PRO 130 130 130 PRO PRO A . n 
A 1 131 PHE 131 131 131 PHE PHE A . n 
A 1 132 PHE 132 132 132 PHE PHE A . n 
A 1 133 GLU 133 133 133 GLU GLU A . n 
A 1 134 ARG 134 134 134 ARG ARG A . n 
A 1 135 GLU 135 135 135 GLU GLU A . n 
A 1 136 VAL 136 136 136 VAL VAL A . n 
A 1 137 TYR 137 137 137 TYR TYR A . n 
A 1 138 GLU 138 138 138 GLU GLU A . n 
A 1 139 TYR 139 139 139 TYR TYR A . n 
A 1 140 PRO 140 140 140 PRO PRO A . n 
A 1 141 ASN 141 141 141 ASN ASN A . n 
A 1 142 GLU 142 142 142 GLU GLU A . n 
A 1 143 GLN 143 143 143 GLN GLN A . n 
A 1 144 ASP 144 144 144 ASP ASP A . n 
A 1 145 ALA 145 145 145 ALA ALA A . n 
A 1 146 THR 146 146 146 THR THR A . n 
A 1 147 ALA 147 147 147 ALA ALA A . n 
A 1 148 LEU 148 148 148 LEU LEU A . n 
A 1 149 TRP 149 149 149 TRP TRP A . n 
A 1 150 TYR 150 150 150 TYR TYR A . n 
A 1 151 HIS 151 151 151 HIS HIS A . n 
A 1 152 ASP 152 152 152 ASP ASP A . n 
A 1 153 HIS 153 153 153 HIS HIS A . n 
A 1 154 ALA 154 154 154 ALA ALA A . n 
A 1 155 MET 155 155 155 MET MET A . n 
A 1 156 ALA 156 156 156 ALA ALA A . n 
A 1 157 ILE 157 157 157 ILE ILE A . n 
A 1 158 THR 158 158 158 THR THR A . n 
A 1 159 ARG 159 159 159 ARG ARG A . n 
A 1 160 LEU 160 160 160 LEU LEU A . n 
A 1 161 ASN 161 161 161 ASN ASN A . n 
A 1 162 VAL 162 162 162 VAL VAL A . n 
A 1 163 TYR 163 163 163 TYR TYR A . n 
A 1 164 ALA 164 164 164 ALA ALA A . n 
A 1 165 GLY 165 165 165 GLY GLY A . n 
A 1 166 LEU 166 166 166 LEU LEU A . n 
A 1 167 VAL 167 167 167 VAL VAL A . n 
A 1 168 GLY 168 168 168 GLY GLY A . n 
A 1 169 LEU 169 169 169 LEU LEU A . n 
A 1 170 TYR 170 170 170 TYR TYR A . n 
A 1 171 PHE 171 171 171 PHE PHE A . n 
A 1 172 ILE 172 172 172 ILE ILE A . n 
A 1 173 ARG 173 173 173 ARG ARG A . n 
A 1 174 ASP 174 174 174 ASP ASP A . n 
A 1 175 ARG 175 175 175 ARG ARG A . n 
A 1 176 GLU 176 176 176 GLU GLU A . n 
A 1 177 GLU 177 177 177 GLU GLU A . n 
A 1 178 ARG 178 178 178 ARG ARG A . n 
A 1 179 SER 179 179 179 SER SER A . n 
A 1 180 LEU 180 180 180 LEU LEU A . n 
A 1 181 ASN 181 181 181 ASN ASN A . n 
A 1 182 LEU 182 182 182 LEU LEU A . n 
A 1 183 PRO 183 183 183 PRO PRO A . n 
A 1 184 LYS 184 184 184 LYS LYS A . n 
A 1 185 GLY 185 185 185 GLY GLY A . n 
A 1 186 GLU 186 186 186 GLU GLU A . n 
A 1 187 TYR 187 187 187 TYR TYR A . n 
A 1 188 GLU 188 188 188 GLU GLU A . n 
A 1 189 ILE 189 189 189 ILE ILE A . n 
A 1 190 PRO 190 190 190 PRO PRO A . n 
A 1 191 LEU 191 191 191 LEU LEU A . n 
A 1 192 LEU 192 192 192 LEU LEU A . n 
A 1 193 ILE 193 193 193 ILE ILE A . n 
A 1 194 GLN 194 194 194 GLN GLN A . n 
A 1 195 ASP 195 195 195 ASP ASP A . n 
A 1 196 LYS 196 196 196 LYS LYS A . n 
A 1 197 SER 197 197 197 SER SER A . n 
A 1 198 PHE 198 198 198 PHE PHE A . n 
A 1 199 HIS 199 199 199 HIS HIS A . n 
A 1 200 GLU 200 200 200 GLU GLU A . n 
A 1 201 ASP 201 201 201 ASP ASP A . n 
A 1 202 GLY 202 202 202 GLY GLY A . n 
A 1 203 SER 203 203 203 SER SER A . n 
A 1 204 LEU 204 204 204 LEU LEU A . n 
A 1 205 PHE 205 205 205 PHE PHE A . n 
A 1 206 TYR 206 206 206 TYR TYR A . n 
A 1 207 PRO 207 207 207 PRO PRO A . n 
A 1 208 ARG 208 208 208 ARG ARG A . n 
A 1 209 GLN 209 209 209 GLN GLN A . n 
A 1 210 PRO 210 210 210 PRO PRO A . n 
A 1 211 ASP 211 211 211 ASP ASP A . n 
A 1 212 ASN 212 212 212 ASN ASN A . n 
A 1 213 PRO 213 213 213 PRO PRO A . n 
A 1 214 SER 214 214 214 SER SER A . n 
A 1 215 PRO 215 215 215 PRO PRO A . n 
A 1 216 ASP 216 216 216 ASP ASP A . n 
A 1 217 LEU 217 217 217 LEU LEU A . n 
A 1 218 PRO 218 218 218 PRO PRO A . n 
A 1 219 ASP 219 219 219 ASP ASP A . n 
A 1 220 PRO 220 220 220 PRO PRO A . n 
A 1 221 SER 221 221 221 SER SER A . n 
A 1 222 ILE 222 222 222 ILE ILE A . n 
A 1 223 VAL 223 223 223 VAL VAL A . n 
A 1 224 PRO 224 224 224 PRO PRO A . n 
A 1 225 ALA 225 225 225 ALA ALA A . n 
A 1 226 PHE 226 226 226 PHE PHE A . n 
A 1 227 CYS 227 227 227 CYS CYS A . n 
A 1 228 GLY 228 228 228 GLY GLY A . n 
A 1 229 ASP 229 229 229 ASP ASP A . n 
A 1 230 THR 230 230 230 THR THR A . n 
A 1 231 ILE 231 231 231 ILE ILE A . n 
A 1 232 LEU 232 232 232 LEU LEU A . n 
A 1 233 VAL 233 233 233 VAL VAL A . n 
A 1 234 ASN 234 234 234 ASN ASN A . n 
A 1 235 GLY 235 235 235 GLY GLY A . n 
A 1 236 LYS 236 236 236 LYS LYS A . n 
A 1 237 VAL 237 237 237 VAL VAL A . n 
A 1 238 TRP 238 238 238 TRP TRP A . n 
A 1 239 PRO 239 239 239 PRO PRO A . n 
A 1 240 TYR 240 240 240 TYR TYR A . n 
A 1 241 ASP 241 241 241 ASP ASP A . n 
A 1 242 GLU 242 242 242 GLU GLU A . n 
A 1 243 LEU 243 243 243 LEU LEU A . n 
A 1 244 GLU 244 244 244 GLU GLU A . n 
A 1 245 PRO 245 245 245 PRO PRO A . n 
A 1 246 ARG 246 246 246 ARG ARG A . n 
A 1 247 LYS 247 247 247 LYS LYS A . n 
A 1 248 TYR 248 248 248 TYR TYR A . n 
A 1 249 ARG 249 249 249 ARG ARG A . n 
A 1 250 PHE 250 250 250 PHE PHE A . n 
A 1 251 ARG 251 251 251 ARG ARG A . n 
A 1 252 ILE 252 252 252 ILE ILE A . n 
A 1 253 LEU 253 253 253 LEU LEU A . n 
A 1 254 ASN 254 254 254 ASN ASN A . n 
A 1 255 ALA 255 255 255 ALA ALA A . n 
A 1 256 SER 256 256 256 SER SER A . n 
A 1 257 ASN 257 257 257 ASN ASN A . n 
A 1 258 THR 258 258 258 THR THR A . n 
A 1 259 ARG 259 259 259 ARG ARG A . n 
A 1 260 ILE 260 260 260 ILE ILE A . n 
A 1 261 PHE 261 261 261 PHE PHE A . n 
A 1 262 GLU 262 262 262 GLU GLU A . n 
A 1 263 LEU 263 263 263 LEU LEU A . n 
A 1 264 TYR 264 264 264 TYR TYR A . n 
A 1 265 PHE 265 265 265 PHE PHE A . n 
A 1 266 ASP 266 266 266 ASP ASP A . n 
A 1 267 HIS 267 267 267 HIS HIS A . n 
A 1 268 ASP 268 268 268 ASP ASP A . n 
A 1 269 ILE 269 269 269 ILE ILE A . n 
A 1 270 THR 270 270 270 THR THR A . n 
A 1 271 PHE 271 271 271 PHE PHE A . n 
A 1 272 HIS 272 272 272 HIS HIS A . n 
A 1 273 GLN 273 273 273 GLN GLN A . n 
A 1 274 ILE 274 274 274 ILE ILE A . n 
A 1 275 GLY 275 275 275 GLY GLY A . n 
A 1 276 THR 276 276 276 THR THR A . n 
A 1 277 ASP 277 277 277 ASP ASP A . n 
A 1 278 GLY 278 278 278 GLY GLY A . n 
A 1 279 GLY 279 279 279 GLY GLY A . n 
A 1 280 LEU 280 280 280 LEU LEU A . n 
A 1 281 LEU 281 281 281 LEU LEU A . n 
A 1 282 GLN 282 282 282 GLN GLN A . n 
A 1 283 HIS 283 283 283 HIS HIS A . n 
A 1 284 PRO 284 284 284 PRO PRO A . n 
A 1 285 VAL 285 285 285 VAL VAL A . n 
A 1 286 LYS 286 286 286 LYS LYS A . n 
A 1 287 VAL 287 287 287 VAL VAL A . n 
A 1 288 ASN 288 288 288 ASN ASN A . n 
A 1 289 GLU 289 289 289 GLU GLU A . n 
A 1 290 LEU 290 290 290 LEU LEU A . n 
A 1 291 VAL 291 291 291 VAL VAL A . n 
A 1 292 ILE 292 292 292 ILE ILE A . n 
A 1 293 ALA 293 293 293 ALA ALA A . n 
A 1 294 PRO 294 294 294 PRO PRO A . n 
A 1 295 ALA 295 295 295 ALA ALA A . n 
A 1 296 GLU 296 296 296 GLU GLU A . n 
A 1 297 ARG 297 297 297 ARG ARG A . n 
A 1 298 CYS 298 298 298 CYS CYS A . n 
A 1 299 ASP 299 299 299 ASP ASP A . n 
A 1 300 ILE 300 300 300 ILE ILE A . n 
A 1 301 ILE 301 301 301 ILE ILE A . n 
A 1 302 VAL 302 302 302 VAL VAL A . n 
A 1 303 ASP 303 303 303 ASP ASP A . n 
A 1 304 PHE 304 304 304 PHE PHE A . n 
A 1 305 SER 305 305 305 SER SER A . n 
A 1 306 ARG 306 306 306 ARG ARG A . n 
A 1 307 ALA 307 307 307 ALA ALA A . n 
A 1 308 GLU 308 308 308 GLU GLU A . n 
A 1 309 GLY 309 309 309 GLY GLY A . n 
A 1 310 LYS 310 310 310 LYS LYS A . n 
A 1 311 THR 311 311 311 THR THR A . n 
A 1 312 VAL 312 312 312 VAL VAL A . n 
A 1 313 THR 313 313 313 THR THR A . n 
A 1 314 LEU 314 314 314 LEU LEU A . n 
A 1 315 LYS 315 315 315 LYS LYS A . n 
A 1 316 ASN 316 316 316 ASN ASN A . n 
A 1 317 ARG 317 317 317 ARG ARG A . n 
A 1 318 ILE 318 318 318 ILE ILE A . n 
A 1 319 GLY 319 319 319 GLY GLY A . n 
A 1 320 CYS 320 320 320 CYS CYS A . n 
A 1 321 SER 321 321 321 SER SER A . n 
A 1 322 GLY 322 322 322 GLY GLY A . n 
A 1 323 GLN 323 323 323 GLN GLN A . n 
A 1 324 ASP 324 324 324 ASP ASP A . n 
A 1 325 ALA 325 325 325 ALA ALA A . n 
A 1 326 ASP 326 326 326 ASP ASP A . n 
A 1 327 PRO 327 327 327 PRO PRO A . n 
A 1 328 ASP 328 327 ?   ?   ?   A A n 
A 1 329 THR 329 328 328 THR THR A . n 
A 1 330 ASP 330 329 329 ASP ASP A . n 
A 1 331 ALA 331 330 330 ALA ALA A . n 
A 1 332 ASN 332 331 331 ASN ASN A . n 
A 1 333 ILE 333 332 332 ILE ILE A . n 
A 1 334 MET 334 333 333 MET MET A . n 
A 1 335 GLN 335 334 334 GLN GLN A . n 
A 1 336 PHE 336 335 335 PHE PHE A . n 
A 1 337 ARG 337 336 336 ARG ARG A . n 
A 1 338 ILE 338 337 337 ILE ILE A . n 
A 1 339 SER 339 338 338 SER SER A . n 
A 1 340 LYS 340 339 339 LYS LYS A . n 
A 1 341 PRO 341 340 340 PRO PRO A . n 
A 1 342 LEU 342 341 341 LEU LEU A . n 
A 1 343 LYS 343 342 342 LYS LYS A . n 
A 1 344 GLN 344 343 343 GLN GLN A . n 
A 1 345 LYS 345 344 344 LYS LYS A . n 
A 1 346 ASP 346 345 345 ASP ASP A . n 
A 1 347 THR 347 346 346 THR THR A . n 
A 1 348 SER 348 347 347 SER SER A . n 
A 1 349 SER 349 348 348 SER SER A . n 
A 1 350 LEU 350 349 349 LEU LEU A . n 
A 1 351 PRO 351 350 350 PRO PRO A . n 
A 1 352 ARG 352 351 351 ARG ARG A . n 
A 1 353 ILE 353 352 352 ILE ILE A . n 
A 1 354 LEU 354 353 353 LEU LEU A . n 
A 1 355 ARG 355 354 354 ARG ARG A . n 
A 1 356 LYS 356 355 355 LYS LYS A . n 
A 1 357 ARG 357 356 356 ARG ARG A . n 
A 1 358 PRO 358 357 357 PRO PRO A . n 
A 1 359 PHE 359 358 358 PHE PHE A . n 
A 1 360 TYR 360 359 ?   ?   ?   A . n 
A 1 361 ARG 361 360 ?   ?   ?   A . n 
A 1 362 ARG 362 361 ?   ?   ?   A . n 
A 1 363 HIS 363 362 362 HIS HIS A . n 
A 1 364 LYS 364 363 363 LYS LYS A . n 
A 1 365 ILE 365 364 364 ILE ILE A . n 
A 1 366 ASN 366 365 365 ASN ASN A . n 
A 1 367 THR 367 366 366 THR THR A . n 
A 1 368 LEU 368 367 367 LEU LEU A . n 
A 1 369 ARG 369 368 368 ARG ARG A . n 
A 1 370 ASN 370 369 369 ASN ASN A . n 
A 1 371 LEU 371 370 370 LEU LEU A . n 
A 1 372 SER 372 371 371 SER SER A . n 
A 1 373 LEU 373 372 372 LEU LEU A . n 
A 1 374 GLY 374 373 373 GLY GLY A . n 
A 1 375 ALA 375 374 374 ALA ALA A . n 
A 1 376 SER 376 375 375 SER SER A . n 
A 1 377 LEU 377 376 376 LEU LEU A . n 
A 1 378 ASP 378 377 377 ASP ASP A . n 
A 1 379 GLN 379 378 378 GLN GLN A . n 
A 1 380 TYR 380 379 379 TYR TYR A . n 
A 1 381 GLY 381 380 380 GLY GLY A . n 
A 1 382 ARG 382 381 381 ARG ARG A . n 
A 1 383 PRO 383 382 382 PRO PRO A . n 
A 1 384 VAL 384 383 383 VAL VAL A . n 
A 1 385 LEU 385 384 384 LEU LEU A . n 
A 1 386 LEU 386 385 385 LEU LEU A . n 
A 1 387 LEU 387 386 386 LEU LEU A . n 
A 1 388 ASN 388 387 387 ASN ASN A . n 
A 1 389 ASN 389 388 388 ASN ASN A . n 
A 1 390 THR 390 389 389 THR THR A . n 
A 1 391 LYS 391 390 390 LYS LYS A . n 
A 1 392 TRP 392 391 391 TRP TRP A . n 
A 1 393 HIS 393 392 392 HIS HIS A . n 
A 1 394 GLU 394 393 393 GLU GLU A . n 
A 1 395 PRO 395 394 394 PRO PRO A . n 
A 1 396 VAL 396 395 395 VAL VAL A . n 
A 1 397 THR 397 396 396 THR THR A . n 
A 1 398 GLU 398 397 397 GLU GLU A . n 
A 1 399 THR 399 398 398 THR THR A . n 
A 1 400 PRO 400 399 399 PRO PRO A . n 
A 1 401 ALA 401 400 400 ALA ALA A . n 
A 1 402 LEU 402 401 401 LEU LEU A . n 
A 1 403 GLY 403 402 402 GLY GLY A . n 
A 1 404 SER 404 403 403 SER SER A . n 
A 1 405 THR 405 404 404 THR THR A . n 
A 1 406 GLU 406 405 405 GLU GLU A . n 
A 1 407 ILE 407 406 406 ILE ILE A . n 
A 1 408 TRP 408 407 407 TRP TRP A . n 
A 1 409 SER 409 408 408 SER SER A . n 
A 1 410 ILE 410 409 409 ILE ILE A . n 
A 1 411 ILE 411 410 410 ILE ILE A . n 
A 1 412 ASN 412 411 411 ASN ASN A . n 
A 1 413 ALA 413 412 412 ALA ALA A . n 
A 1 414 GLY 414 413 413 GLY GLY A . n 
A 1 415 ARG 415 414 414 ARG ARG A . n 
A 1 416 ALA 416 415 415 ALA ALA A . n 
A 1 417 ILE 417 416 416 ILE ILE A . n 
A 1 418 HIS 418 417 417 HIS HIS A . n 
A 1 419 PRO 419 418 418 PRO PRO A . n 
A 1 420 ILE 420 419 419 ILE ILE A . n 
A 1 421 HIS 421 420 420 HIS HIS A . n 
A 1 422 LEU 422 421 421 LEU LEU A . n 
A 1 423 HIS 423 422 422 HIS HIS A . n 
A 1 424 LEU 424 423 423 LEU LEU A . n 
A 1 425 VAL 425 424 424 VAL VAL A . n 
A 1 426 GLN 426 425 425 GLN GLN A . n 
A 1 427 PHE 427 426 426 PHE PHE A . n 
A 1 428 LEU 428 427 427 LEU LEU A . n 
A 1 429 ILE 429 428 428 ILE ILE A . n 
A 1 430 LEU 430 429 429 LEU LEU A . n 
A 1 431 ASP 431 430 430 ASP ASP A . n 
A 1 432 HIS 432 431 431 HIS HIS A . n 
A 1 433 ARG 433 432 432 ARG ARG A . n 
A 1 434 PRO 434 433 433 PRO PRO A . n 
A 1 435 PHE 435 434 434 PHE PHE A . n 
A 1 436 ASP 436 435 435 ASP ASP A . n 
A 1 437 ILE 437 436 436 ILE ILE A . n 
A 1 438 GLU 438 437 437 GLU GLU A . n 
A 1 439 ARG 439 438 438 ARG ARG A . n 
A 1 440 TYR 440 439 439 TYR TYR A . n 
A 1 441 GLN 441 440 440 GLN GLN A . n 
A 1 442 GLU 442 441 441 GLU GLU A . n 
A 1 443 ASN 443 442 442 ASN ASN A . n 
A 1 444 GLY 444 443 443 GLY GLY A . n 
A 1 445 GLU 445 444 444 GLU GLU A . n 
A 1 446 LEU 446 445 445 LEU LEU A . n 
A 1 447 VAL 447 446 446 VAL VAL A . n 
A 1 448 PHE 448 447 447 PHE PHE A . n 
A 1 449 THR 449 448 448 THR THR A . n 
A 1 450 GLY 450 449 449 GLY GLY A . n 
A 1 451 PRO 451 450 450 PRO PRO A . n 
A 1 452 ALA 452 451 451 ALA ALA A . n 
A 1 453 ALA 453 452 452 ALA ALA A . n 
A 1 454 PRO 454 453 453 PRO PRO A . n 
A 1 455 PRO 455 454 454 PRO PRO A . n 
A 1 456 ALA 456 455 455 ALA ALA A . n 
A 1 457 GLN 457 456 456 GLN GLN A . n 
A 1 458 ASN 458 457 457 ASN ASN A . n 
A 1 459 GLU 459 458 458 GLU GLU A . n 
A 1 460 LYS 460 459 459 LYS LYS A . n 
A 1 461 GLY 461 460 460 GLY GLY A . n 
A 1 462 LEU 462 461 461 LEU LEU A . n 
A 1 463 LYS 463 462 462 LYS LYS A . n 
A 1 464 ASP 464 463 463 ASP ASP A . n 
A 1 465 THR 465 464 464 THR THR A . n 
A 1 466 VAL 466 465 465 VAL VAL A . n 
A 1 467 LYS 467 466 466 LYS LYS A . n 
A 1 468 VAL 468 467 467 VAL VAL A . n 
A 1 469 PRO 469 468 468 PRO PRO A . n 
A 1 470 PRO 470 469 469 PRO PRO A . n 
A 1 471 GLY 471 470 470 GLY GLY A . n 
A 1 472 SER 472 471 471 SER SER A . n 
A 1 473 VAL 473 472 472 VAL VAL A . n 
A 1 474 THR 474 473 473 THR THR A . n 
A 1 475 ARG 475 474 474 ARG ARG A . n 
A 1 476 ILE 476 475 475 ILE ILE A . n 
A 1 477 ILE 477 476 476 ILE ILE A . n 
A 1 478 ALA 478 477 477 ALA ALA A . n 
A 1 479 THR 479 478 478 THR THR A . n 
A 1 480 PHE 480 479 479 PHE PHE A . n 
A 1 481 ALA 481 480 480 ALA ALA A . n 
A 1 482 PRO 482 481 481 PRO PRO A . n 
A 1 483 TYR 483 482 482 TYR TYR A . n 
A 1 484 SER 484 483 483 SER SER A . n 
A 1 485 GLY 485 484 484 GLY GLY A . n 
A 1 486 ARG 486 485 485 ARG ARG A . n 
A 1 487 TYR 487 486 486 TYR TYR A . n 
A 1 488 VAL 488 487 487 VAL VAL A . n 
A 1 489 TRP 489 488 488 TRP TRP A . n 
A 1 490 HIS 490 489 489 HIS HIS A . n 
A 1 491 CYS 491 490 490 CYS CYS A . n 
A 1 492 HIS 492 491 491 HIS HIS A . n 
A 1 493 ILE 493 492 492 ILE ILE A . n 
A 1 494 LEU 494 493 493 LEU LEU A . n 
A 1 495 GLU 495 494 494 GLU GLU A . n 
A 1 496 HIS 496 495 495 HIS HIS A . n 
A 1 497 GLU 497 496 496 GLU GLU A . n 
A 1 498 ASP 498 497 497 ASP ASP A . n 
A 1 499 TYR 499 498 498 TYR TYR A . n 
A 1 500 ASP 500 499 499 ASP ASP A . n 
A 1 501 MET 501 500 500 MET MET A . n 
A 1 502 MET 502 501 501 MET MET A . n 
A 1 503 ARG 503 502 502 ARG ARG A . n 
A 1 504 PRO 504 503 503 PRO PRO A . n 
A 1 505 LEU 505 504 504 LEU LEU A . n 
A 1 506 GLU 506 505 505 GLU GLU A . n 
A 1 507 VAL 507 506 506 VAL VAL A . n 
A 1 508 THR 508 507 507 THR THR A . n 
A 1 509 ASP 509 508 508 ASP ASP A . n 
A 1 510 ILE 510 509 509 ILE ILE A . n 
A 1 511 ARG 511 510 510 ARG ARG A . n 
A 1 512 HIS 512 511 511 HIS HIS A . n 
A 1 513 GLN 513 512 512 GLN GLN A . n 
A 1 514 GLU 514 513 ?   ?   ?   A . n 
A 1 515 PHE 515 514 ?   ?   ?   A . n 
A 1 516 GLU 516 515 ?   ?   ?   A . n 
A 1 517 ALA 517 516 ?   ?   ?   A . n 
A 1 518 TRP 518 517 ?   ?   ?   A . n 
A 1 519 ALA 519 518 ?   ?   ?   A . n 
A 1 520 ARG 520 519 ?   ?   ?   A . n 
A 1 521 THR 521 520 ?   ?   ?   A . n 
A 1 522 LYS 522 521 ?   ?   ?   A . n 
A 1 523 THR 523 522 ?   ?   ?   A . n 
A 1 524 HIS 524 523 ?   ?   ?   A . n 
A 1 525 LEU 525 524 ?   ?   ?   A . n 
A 1 526 ARG 526 525 ?   ?   ?   A . n 
A 1 527 ARG 527 526 ?   ?   ?   A . n 
A 1 528 GLY 528 527 ?   ?   ?   A . n 
A 1 529 SER 529 528 ?   ?   ?   A . n 
A 1 530 GLU 530 529 ?   ?   ?   A . n 
B 1 1   MET 1   1   ?   ?   ?   B . n 
B 1 2   LYS 2   2   2   LYS LYS B . n 
B 1 3   LEU 3   3   3   LEU LEU B . n 
B 1 4   GLU 4   4   4   GLU GLU B . n 
B 1 5   LYS 5   5   5   LYS LYS B . n 
B 1 6   PHE 6   6   6   PHE PHE B . n 
B 1 7   VAL 7   7   7   VAL VAL B . n 
B 1 8   ASP 8   8   8   ASP ASP B . n 
B 1 9   LYS 9   9   9   LYS LYS B . n 
B 1 10  LEU 10  10  10  LEU LEU B . n 
B 1 11  PRO 11  11  11  PRO PRO B . n 
B 1 12  ILE 12  12  12  ILE ILE B . n 
B 1 13  PRO 13  13  13  PRO PRO B . n 
B 1 14  LYS 14  14  14  LYS LYS B . n 
B 1 15  VAL 15  15  15  VAL VAL B . n 
B 1 16  LEU 16  16  16  LEU LEU B . n 
B 1 17  LYS 17  17  17  LYS LYS B . n 
B 1 18  PRO 18  18  18  PRO PRO B . n 
B 1 19  HIS 19  19  19  HIS HIS B . n 
B 1 20  SER 20  20  20  SER SER B . n 
B 1 21  LYS 21  21  21  LYS LYS B . n 
B 1 22  SER 22  22  22  SER SER B . n 
B 1 23  LYS 23  23  23  LYS LYS B . n 
B 1 24  GLU 24  24  24  GLU GLU B . n 
B 1 25  MET 25  25  25  MET MET B . n 
B 1 26  THR 26  26  26  THR THR B . n 
B 1 27  TYR 27  27  27  TYR TYR B . n 
B 1 28  TYR 28  28  28  TYR TYR B . n 
B 1 29  GLU 29  29  29  GLU GLU B . n 
B 1 30  VAL 30  30  30  VAL VAL B . n 
B 1 31  THR 31  31  31  THR THR B . n 
B 1 32  MET 32  32  32  MET MET B . n 
B 1 33  LYS 33  33  33  LYS LYS B . n 
B 1 34  GLU 34  34  34  GLU GLU B . n 
B 1 35  PHE 35  35  35  PHE PHE B . n 
B 1 36  GLN 36  36  36  GLN GLN B . n 
B 1 37  GLN 37  37  37  GLN GLN B . n 
B 1 38  GLN 38  38  38  GLN GLN B . n 
B 1 39  LEU 39  39  39  LEU LEU B . n 
B 1 40  HIS 40  40  40  HIS HIS B . n 
B 1 41  ARG 41  41  41  ARG ARG B . n 
B 1 42  ASP 42  42  42  ASP ASP B . n 
B 1 43  LEU 43  43  43  LEU LEU B . n 
B 1 44  PRO 44  44  44  PRO PRO B . n 
B 1 45  PRO 45  45  45  PRO PRO B . n 
B 1 46  THR 46  46  46  THR THR B . n 
B 1 47  ARG 47  47  47  ARG ARG B . n 
B 1 48  LEU 48  48  48  LEU LEU B . n 
B 1 49  PHE 49  49  49  PHE PHE B . n 
B 1 50  GLY 50  50  50  GLY GLY B . n 
B 1 51  TYR 51  51  51  TYR TYR B . n 
B 1 52  ASN 52  52  52  ASN ASN B . n 
B 1 53  GLY 53  53  53  GLY GLY B . n 
B 1 54  VAL 54  54  54  VAL VAL B . n 
B 1 55  TYR 55  55  55  TYR TYR B . n 
B 1 56  PRO 56  56  56  PRO PRO B . n 
B 1 57  GLY 57  57  57  GLY GLY B . n 
B 1 58  PRO 58  58  58  PRO PRO B . n 
B 1 59  THR 59  59  59  THR THR B . n 
B 1 60  PHE 60  60  60  PHE PHE B . n 
B 1 61  GLU 61  61  61  GLU GLU B . n 
B 1 62  VAL 62  62  62  VAL VAL B . n 
B 1 63  GLN 63  63  63  GLN GLN B . n 
B 1 64  LYS 64  64  64  LYS LYS B . n 
B 1 65  HIS 65  65  65  HIS HIS B . n 
B 1 66  GLU 66  66  66  GLU GLU B . n 
B 1 67  LYS 67  67  67  LYS LYS B . n 
B 1 68  VAL 68  68  68  VAL VAL B . n 
B 1 69  ALA 69  69  69  ALA ALA B . n 
B 1 70  VAL 70  70  70  VAL VAL B . n 
B 1 71  LYS 71  71  71  LYS LYS B . n 
B 1 72  TRP 72  72  72  TRP TRP B . n 
B 1 73  LEU 73  73  73  LEU LEU B . n 
B 1 74  ASN 74  74  74  ASN ASN B . n 
B 1 75  LYS 75  75  75  LYS LYS B . n 
B 1 76  LEU 76  76  76  LEU LEU B . n 
B 1 77  PRO 77  77  77  PRO PRO B . n 
B 1 78  ASP 78  78  78  ASP ASP B . n 
B 1 79  HIS 79  79  79  HIS HIS B . n 
B 1 80  HIS 80  80  80  HIS HIS B . n 
B 1 81  PHE 81  81  81  PHE PHE B . n 
B 1 82  LEU 82  82  82  LEU LEU B . n 
B 1 83  PRO 83  83  83  PRO PRO B . n 
B 1 84  VAL 84  84  84  VAL VAL B . n 
B 1 85  ASP 85  85  85  ASP ASP B . n 
B 1 86  HIS 86  86  86  HIS HIS B . n 
B 1 87  THR 87  87  87  THR THR B . n 
B 1 88  ILE 88  88  88  ILE ILE B . n 
B 1 89  HIS 89  89  89  HIS HIS B . n 
B 1 90  ASP 90  90  ?   ?   ?   B . n 
B 1 91  ASP 91  91  ?   ?   ?   B . n 
B 1 92  GLY 92  92  ?   ?   ?   B . n 
B 1 93  HIS 93  93  ?   ?   ?   B . n 
B 1 94  HIS 94  94  ?   ?   ?   B . n 
B 1 95  GLU 95  95  ?   ?   ?   B . n 
B 1 96  HIS 96  96  ?   ?   ?   B . n 
B 1 97  GLU 97  97  97  GLU GLU B . n 
B 1 98  VAL 98  98  98  VAL VAL B . n 
B 1 99  LYS 99  99  99  LYS LYS B . n 
B 1 100 THR 100 100 100 THR THR B . n 
B 1 101 VAL 101 101 101 VAL VAL B . n 
B 1 102 VAL 102 102 102 VAL VAL B . n 
B 1 103 HIS 103 103 103 HIS HIS B . n 
B 1 104 LEU 104 104 104 LEU LEU B . n 
B 1 105 HIS 105 105 105 HIS HIS B . n 
B 1 106 GLY 106 106 106 GLY GLY B . n 
B 1 107 GLY 107 107 107 GLY GLY B . n 
B 1 108 ARG 108 108 108 ARG ARG B . n 
B 1 109 THR 109 109 109 THR THR B . n 
B 1 110 PRO 110 110 110 PRO PRO B . n 
B 1 111 PRO 111 111 111 PRO PRO B . n 
B 1 112 ASP 112 112 112 ASP ASP B . n 
B 1 113 SER 113 113 113 SER SER B . n 
B 1 114 ASP 114 114 114 ASP ASP B . n 
B 1 115 GLY 115 115 115 GLY GLY B . n 
B 1 116 TYR 116 116 116 TYR TYR B . n 
B 1 117 PRO 117 117 117 PRO PRO B . n 
B 1 118 GLU 118 118 118 GLU GLU B . n 
B 1 119 ALA 119 119 119 ALA ALA B . n 
B 1 120 TRP 120 120 120 TRP TRP B . n 
B 1 121 TYR 121 121 121 TYR TYR B . n 
B 1 122 THR 122 122 122 THR THR B . n 
B 1 123 LYS 123 123 123 LYS LYS B . n 
B 1 124 ASP 124 124 124 ASP ASP B . n 
B 1 125 PHE 125 125 125 PHE PHE B . n 
B 1 126 GLN 126 126 126 GLN GLN B . n 
B 1 127 VAL 127 127 127 VAL VAL B . n 
B 1 128 LYS 128 128 128 LYS LYS B . n 
B 1 129 GLY 129 129 129 GLY GLY B . n 
B 1 130 PRO 130 130 130 PRO PRO B . n 
B 1 131 PHE 131 131 131 PHE PHE B . n 
B 1 132 PHE 132 132 132 PHE PHE B . n 
B 1 133 GLU 133 133 133 GLU GLU B . n 
B 1 134 ARG 134 134 134 ARG ARG B . n 
B 1 135 GLU 135 135 135 GLU GLU B . n 
B 1 136 VAL 136 136 136 VAL VAL B . n 
B 1 137 TYR 137 137 137 TYR TYR B . n 
B 1 138 GLU 138 138 138 GLU GLU B . n 
B 1 139 TYR 139 139 139 TYR TYR B . n 
B 1 140 PRO 140 140 140 PRO PRO B . n 
B 1 141 ASN 141 141 141 ASN ASN B . n 
B 1 142 GLU 142 142 142 GLU GLU B . n 
B 1 143 GLN 143 143 143 GLN GLN B . n 
B 1 144 ASP 144 144 144 ASP ASP B . n 
B 1 145 ALA 145 145 145 ALA ALA B . n 
B 1 146 THR 146 146 146 THR THR B . n 
B 1 147 ALA 147 147 147 ALA ALA B . n 
B 1 148 LEU 148 148 148 LEU LEU B . n 
B 1 149 TRP 149 149 149 TRP TRP B . n 
B 1 150 TYR 150 150 150 TYR TYR B . n 
B 1 151 HIS 151 151 151 HIS HIS B . n 
B 1 152 ASP 152 152 152 ASP ASP B . n 
B 1 153 HIS 153 153 153 HIS HIS B . n 
B 1 154 ALA 154 154 154 ALA ALA B . n 
B 1 155 MET 155 155 155 MET MET B . n 
B 1 156 ALA 156 156 156 ALA ALA B . n 
B 1 157 ILE 157 157 157 ILE ILE B . n 
B 1 158 THR 158 158 158 THR THR B . n 
B 1 159 ARG 159 159 159 ARG ARG B . n 
B 1 160 LEU 160 160 160 LEU LEU B . n 
B 1 161 ASN 161 161 161 ASN ASN B . n 
B 1 162 VAL 162 162 162 VAL VAL B . n 
B 1 163 TYR 163 163 163 TYR TYR B . n 
B 1 164 ALA 164 164 164 ALA ALA B . n 
B 1 165 GLY 165 165 165 GLY GLY B . n 
B 1 166 LEU 166 166 166 LEU LEU B . n 
B 1 167 VAL 167 167 167 VAL VAL B . n 
B 1 168 GLY 168 168 168 GLY GLY B . n 
B 1 169 LEU 169 169 169 LEU LEU B . n 
B 1 170 TYR 170 170 170 TYR TYR B . n 
B 1 171 PHE 171 171 171 PHE PHE B . n 
B 1 172 ILE 172 172 172 ILE ILE B . n 
B 1 173 ARG 173 173 173 ARG ARG B . n 
B 1 174 ASP 174 174 174 ASP ASP B . n 
B 1 175 ARG 175 175 175 ARG ARG B . n 
B 1 176 GLU 176 176 176 GLU GLU B . n 
B 1 177 GLU 177 177 177 GLU GLU B . n 
B 1 178 ARG 178 178 178 ARG ARG B . n 
B 1 179 SER 179 179 179 SER SER B . n 
B 1 180 LEU 180 180 180 LEU LEU B . n 
B 1 181 ASN 181 181 181 ASN ASN B . n 
B 1 182 LEU 182 182 182 LEU LEU B . n 
B 1 183 PRO 183 183 183 PRO PRO B . n 
B 1 184 LYS 184 184 184 LYS LYS B . n 
B 1 185 GLY 185 185 185 GLY GLY B . n 
B 1 186 GLU 186 186 186 GLU GLU B . n 
B 1 187 TYR 187 187 187 TYR TYR B . n 
B 1 188 GLU 188 188 188 GLU GLU B . n 
B 1 189 ILE 189 189 189 ILE ILE B . n 
B 1 190 PRO 190 190 190 PRO PRO B . n 
B 1 191 LEU 191 191 191 LEU LEU B . n 
B 1 192 LEU 192 192 192 LEU LEU B . n 
B 1 193 ILE 193 193 193 ILE ILE B . n 
B 1 194 GLN 194 194 194 GLN GLN B . n 
B 1 195 ASP 195 195 195 ASP ASP B . n 
B 1 196 LYS 196 196 196 LYS LYS B . n 
B 1 197 SER 197 197 197 SER SER B . n 
B 1 198 PHE 198 198 198 PHE PHE B . n 
B 1 199 HIS 199 199 199 HIS HIS B . n 
B 1 200 GLU 200 200 200 GLU GLU B . n 
B 1 201 ASP 201 201 201 ASP ASP B . n 
B 1 202 GLY 202 202 202 GLY GLY B . n 
B 1 203 SER 203 203 203 SER SER B . n 
B 1 204 LEU 204 204 204 LEU LEU B . n 
B 1 205 PHE 205 205 205 PHE PHE B . n 
B 1 206 TYR 206 206 206 TYR TYR B . n 
B 1 207 PRO 207 207 207 PRO PRO B . n 
B 1 208 ARG 208 208 208 ARG ARG B . n 
B 1 209 GLN 209 209 209 GLN GLN B . n 
B 1 210 PRO 210 210 210 PRO PRO B . n 
B 1 211 ASP 211 211 211 ASP ASP B . n 
B 1 212 ASN 212 212 212 ASN ASN B . n 
B 1 213 PRO 213 213 213 PRO PRO B . n 
B 1 214 SER 214 214 214 SER SER B . n 
B 1 215 PRO 215 215 215 PRO PRO B . n 
B 1 216 ASP 216 216 216 ASP ASP B . n 
B 1 217 LEU 217 217 217 LEU LEU B . n 
B 1 218 PRO 218 218 218 PRO PRO B . n 
B 1 219 ASP 219 219 219 ASP ASP B . n 
B 1 220 PRO 220 220 220 PRO PRO B . n 
B 1 221 SER 221 221 221 SER SER B . n 
B 1 222 ILE 222 222 222 ILE ILE B . n 
B 1 223 VAL 223 223 223 VAL VAL B . n 
B 1 224 PRO 224 224 224 PRO PRO B . n 
B 1 225 ALA 225 225 225 ALA ALA B . n 
B 1 226 PHE 226 226 226 PHE PHE B . n 
B 1 227 CYS 227 227 227 CYS CYS B . n 
B 1 228 GLY 228 228 228 GLY GLY B . n 
B 1 229 ASP 229 229 229 ASP ASP B . n 
B 1 230 THR 230 230 230 THR THR B . n 
B 1 231 ILE 231 231 231 ILE ILE B . n 
B 1 232 LEU 232 232 232 LEU LEU B . n 
B 1 233 VAL 233 233 233 VAL VAL B . n 
B 1 234 ASN 234 234 234 ASN ASN B . n 
B 1 235 GLY 235 235 235 GLY GLY B . n 
B 1 236 LYS 236 236 236 LYS LYS B . n 
B 1 237 VAL 237 237 237 VAL VAL B . n 
B 1 238 TRP 238 238 238 TRP TRP B . n 
B 1 239 PRO 239 239 239 PRO PRO B . n 
B 1 240 TYR 240 240 240 TYR TYR B . n 
B 1 241 ASP 241 241 241 ASP ASP B . n 
B 1 242 GLU 242 242 242 GLU GLU B . n 
B 1 243 LEU 243 243 243 LEU LEU B . n 
B 1 244 GLU 244 244 244 GLU GLU B . n 
B 1 245 PRO 245 245 245 PRO PRO B . n 
B 1 246 ARG 246 246 246 ARG ARG B . n 
B 1 247 LYS 247 247 247 LYS LYS B . n 
B 1 248 TYR 248 248 248 TYR TYR B . n 
B 1 249 ARG 249 249 249 ARG ARG B . n 
B 1 250 PHE 250 250 250 PHE PHE B . n 
B 1 251 ARG 251 251 251 ARG ARG B . n 
B 1 252 ILE 252 252 252 ILE ILE B . n 
B 1 253 LEU 253 253 253 LEU LEU B . n 
B 1 254 ASN 254 254 254 ASN ASN B . n 
B 1 255 ALA 255 255 255 ALA ALA B . n 
B 1 256 SER 256 256 256 SER SER B . n 
B 1 257 ASN 257 257 257 ASN ASN B . n 
B 1 258 THR 258 258 258 THR THR B . n 
B 1 259 ARG 259 259 259 ARG ARG B . n 
B 1 260 ILE 260 260 260 ILE ILE B . n 
B 1 261 PHE 261 261 261 PHE PHE B . n 
B 1 262 GLU 262 262 262 GLU GLU B . n 
B 1 263 LEU 263 263 263 LEU LEU B . n 
B 1 264 TYR 264 264 264 TYR TYR B . n 
B 1 265 PHE 265 265 265 PHE PHE B . n 
B 1 266 ASP 266 266 266 ASP ASP B . n 
B 1 267 HIS 267 267 267 HIS HIS B . n 
B 1 268 ASP 268 268 268 ASP ASP B . n 
B 1 269 ILE 269 269 269 ILE ILE B . n 
B 1 270 THR 270 270 270 THR THR B . n 
B 1 271 PHE 271 271 271 PHE PHE B . n 
B 1 272 HIS 272 272 272 HIS HIS B . n 
B 1 273 GLN 273 273 273 GLN GLN B . n 
B 1 274 ILE 274 274 274 ILE ILE B . n 
B 1 275 GLY 275 275 275 GLY GLY B . n 
B 1 276 THR 276 276 276 THR THR B . n 
B 1 277 ASP 277 277 277 ASP ASP B . n 
B 1 278 GLY 278 278 278 GLY GLY B . n 
B 1 279 GLY 279 279 279 GLY GLY B . n 
B 1 280 LEU 280 280 280 LEU LEU B . n 
B 1 281 LEU 281 281 281 LEU LEU B . n 
B 1 282 GLN 282 282 282 GLN GLN B . n 
B 1 283 HIS 283 283 283 HIS HIS B . n 
B 1 284 PRO 284 284 284 PRO PRO B . n 
B 1 285 VAL 285 285 285 VAL VAL B . n 
B 1 286 LYS 286 286 286 LYS LYS B . n 
B 1 287 VAL 287 287 287 VAL VAL B . n 
B 1 288 ASN 288 288 288 ASN ASN B . n 
B 1 289 GLU 289 289 289 GLU GLU B . n 
B 1 290 LEU 290 290 290 LEU LEU B . n 
B 1 291 VAL 291 291 291 VAL VAL B . n 
B 1 292 ILE 292 292 292 ILE ILE B . n 
B 1 293 ALA 293 293 293 ALA ALA B . n 
B 1 294 PRO 294 294 294 PRO PRO B . n 
B 1 295 ALA 295 295 295 ALA ALA B . n 
B 1 296 GLU 296 296 296 GLU GLU B . n 
B 1 297 ARG 297 297 297 ARG ARG B . n 
B 1 298 CYS 298 298 298 CYS CYS B . n 
B 1 299 ASP 299 299 299 ASP ASP B . n 
B 1 300 ILE 300 300 300 ILE ILE B . n 
B 1 301 ILE 301 301 301 ILE ILE B . n 
B 1 302 VAL 302 302 302 VAL VAL B . n 
B 1 303 ASP 303 303 303 ASP ASP B . n 
B 1 304 PHE 304 304 304 PHE PHE B . n 
B 1 305 SER 305 305 305 SER SER B . n 
B 1 306 ARG 306 306 306 ARG ARG B . n 
B 1 307 ALA 307 307 307 ALA ALA B . n 
B 1 308 GLU 308 308 308 GLU GLU B . n 
B 1 309 GLY 309 309 309 GLY GLY B . n 
B 1 310 LYS 310 310 310 LYS LYS B . n 
B 1 311 THR 311 311 311 THR THR B . n 
B 1 312 VAL 312 312 312 VAL VAL B . n 
B 1 313 THR 313 313 313 THR THR B . n 
B 1 314 LEU 314 314 314 LEU LEU B . n 
B 1 315 LYS 315 315 315 LYS LYS B . n 
B 1 316 ASN 316 316 316 ASN ASN B . n 
B 1 317 ARG 317 317 317 ARG ARG B . n 
B 1 318 ILE 318 318 318 ILE ILE B . n 
B 1 319 GLY 319 319 319 GLY GLY B . n 
B 1 320 CYS 320 320 320 CYS CYS B . n 
B 1 321 SER 321 321 321 SER SER B . n 
B 1 322 GLY 322 322 322 GLY GLY B . n 
B 1 323 GLN 323 323 323 GLN GLN B . n 
B 1 324 ASP 324 324 324 ASP ASP B . n 
B 1 325 ALA 325 325 325 ALA ALA B . n 
B 1 326 ASP 326 326 326 ASP ASP B . n 
B 1 327 PRO 327 327 327 PRO PRO B . n 
B 1 328 ASP 328 327 ?   ?   ?   B A n 
B 1 329 THR 329 328 328 THR THR B . n 
B 1 330 ASP 330 329 329 ASP ASP B . n 
B 1 331 ALA 331 330 330 ALA ALA B . n 
B 1 332 ASN 332 331 331 ASN ASN B . n 
B 1 333 ILE 333 332 332 ILE ILE B . n 
B 1 334 MET 334 333 333 MET MET B . n 
B 1 335 GLN 335 334 334 GLN GLN B . n 
B 1 336 PHE 336 335 335 PHE PHE B . n 
B 1 337 ARG 337 336 336 ARG ARG B . n 
B 1 338 ILE 338 337 337 ILE ILE B . n 
B 1 339 SER 339 338 338 SER SER B . n 
B 1 340 LYS 340 339 339 LYS LYS B . n 
B 1 341 PRO 341 340 340 PRO PRO B . n 
B 1 342 LEU 342 341 341 LEU LEU B . n 
B 1 343 LYS 343 342 342 LYS LYS B . n 
B 1 344 GLN 344 343 343 GLN GLN B . n 
B 1 345 LYS 345 344 344 LYS LYS B . n 
B 1 346 ASP 346 345 345 ASP ASP B . n 
B 1 347 THR 347 346 346 THR THR B . n 
B 1 348 SER 348 347 347 SER SER B . n 
B 1 349 SER 349 348 348 SER SER B . n 
B 1 350 LEU 350 349 349 LEU LEU B . n 
B 1 351 PRO 351 350 350 PRO PRO B . n 
B 1 352 ARG 352 351 351 ARG ARG B . n 
B 1 353 ILE 353 352 352 ILE ILE B . n 
B 1 354 LEU 354 353 353 LEU LEU B . n 
B 1 355 ARG 355 354 354 ARG ARG B . n 
B 1 356 LYS 356 355 355 LYS LYS B . n 
B 1 357 ARG 357 356 356 ARG ARG B . n 
B 1 358 PRO 358 357 357 PRO PRO B . n 
B 1 359 PHE 359 358 358 PHE PHE B . n 
B 1 360 TYR 360 359 ?   ?   ?   B . n 
B 1 361 ARG 361 360 ?   ?   ?   B . n 
B 1 362 ARG 362 361 ?   ?   ?   B . n 
B 1 363 HIS 363 362 362 HIS HIS B . n 
B 1 364 LYS 364 363 363 LYS LYS B . n 
B 1 365 ILE 365 364 364 ILE ILE B . n 
B 1 366 ASN 366 365 365 ASN ASN B . n 
B 1 367 THR 367 366 366 THR THR B . n 
B 1 368 LEU 368 367 367 LEU LEU B . n 
B 1 369 ARG 369 368 368 ARG ARG B . n 
B 1 370 ASN 370 369 369 ASN ASN B . n 
B 1 371 LEU 371 370 370 LEU LEU B . n 
B 1 372 SER 372 371 371 SER SER B . n 
B 1 373 LEU 373 372 372 LEU LEU B . n 
B 1 374 GLY 374 373 373 GLY GLY B . n 
B 1 375 ALA 375 374 374 ALA ALA B . n 
B 1 376 SER 376 375 375 SER SER B . n 
B 1 377 LEU 377 376 376 LEU LEU B . n 
B 1 378 ASP 378 377 377 ASP ASP B . n 
B 1 379 GLN 379 378 378 GLN GLN B . n 
B 1 380 TYR 380 379 379 TYR TYR B . n 
B 1 381 GLY 381 380 380 GLY GLY B . n 
B 1 382 ARG 382 381 381 ARG ARG B . n 
B 1 383 PRO 383 382 382 PRO PRO B . n 
B 1 384 VAL 384 383 383 VAL VAL B . n 
B 1 385 LEU 385 384 384 LEU LEU B . n 
B 1 386 LEU 386 385 385 LEU LEU B . n 
B 1 387 LEU 387 386 386 LEU LEU B . n 
B 1 388 ASN 388 387 387 ASN ASN B . n 
B 1 389 ASN 389 388 388 ASN ASN B . n 
B 1 390 THR 390 389 389 THR THR B . n 
B 1 391 LYS 391 390 390 LYS LYS B . n 
B 1 392 TRP 392 391 391 TRP TRP B . n 
B 1 393 HIS 393 392 392 HIS HIS B . n 
B 1 394 GLU 394 393 393 GLU GLU B . n 
B 1 395 PRO 395 394 394 PRO PRO B . n 
B 1 396 VAL 396 395 395 VAL VAL B . n 
B 1 397 THR 397 396 396 THR THR B . n 
B 1 398 GLU 398 397 397 GLU GLU B . n 
B 1 399 THR 399 398 398 THR THR B . n 
B 1 400 PRO 400 399 399 PRO PRO B . n 
B 1 401 ALA 401 400 400 ALA ALA B . n 
B 1 402 LEU 402 401 401 LEU LEU B . n 
B 1 403 GLY 403 402 402 GLY GLY B . n 
B 1 404 SER 404 403 403 SER SER B . n 
B 1 405 THR 405 404 404 THR THR B . n 
B 1 406 GLU 406 405 405 GLU GLU B . n 
B 1 407 ILE 407 406 406 ILE ILE B . n 
B 1 408 TRP 408 407 407 TRP TRP B . n 
B 1 409 SER 409 408 408 SER SER B . n 
B 1 410 ILE 410 409 409 ILE ILE B . n 
B 1 411 ILE 411 410 410 ILE ILE B . n 
B 1 412 ASN 412 411 411 ASN ASN B . n 
B 1 413 ALA 413 412 412 ALA ALA B . n 
B 1 414 GLY 414 413 413 GLY GLY B . n 
B 1 415 ARG 415 414 414 ARG ARG B . n 
B 1 416 ALA 416 415 415 ALA ALA B . n 
B 1 417 ILE 417 416 416 ILE ILE B . n 
B 1 418 HIS 418 417 417 HIS HIS B . n 
B 1 419 PRO 419 418 418 PRO PRO B . n 
B 1 420 ILE 420 419 419 ILE ILE B . n 
B 1 421 HIS 421 420 420 HIS HIS B . n 
B 1 422 LEU 422 421 421 LEU LEU B . n 
B 1 423 HIS 423 422 422 HIS HIS B . n 
B 1 424 LEU 424 423 423 LEU LEU B . n 
B 1 425 VAL 425 424 424 VAL VAL B . n 
B 1 426 GLN 426 425 425 GLN GLN B . n 
B 1 427 PHE 427 426 426 PHE PHE B . n 
B 1 428 LEU 428 427 427 LEU LEU B . n 
B 1 429 ILE 429 428 428 ILE ILE B . n 
B 1 430 LEU 430 429 429 LEU LEU B . n 
B 1 431 ASP 431 430 430 ASP ASP B . n 
B 1 432 HIS 432 431 431 HIS HIS B . n 
B 1 433 ARG 433 432 432 ARG ARG B . n 
B 1 434 PRO 434 433 433 PRO PRO B . n 
B 1 435 PHE 435 434 434 PHE PHE B . n 
B 1 436 ASP 436 435 435 ASP ASP B . n 
B 1 437 ILE 437 436 436 ILE ILE B . n 
B 1 438 GLU 438 437 437 GLU GLU B . n 
B 1 439 ARG 439 438 438 ARG ARG B . n 
B 1 440 TYR 440 439 439 TYR TYR B . n 
B 1 441 GLN 441 440 440 GLN GLN B . n 
B 1 442 GLU 442 441 441 GLU GLU B . n 
B 1 443 ASN 443 442 442 ASN ASN B . n 
B 1 444 GLY 444 443 443 GLY GLY B . n 
B 1 445 GLU 445 444 444 GLU GLU B . n 
B 1 446 LEU 446 445 445 LEU LEU B . n 
B 1 447 VAL 447 446 446 VAL VAL B . n 
B 1 448 PHE 448 447 447 PHE PHE B . n 
B 1 449 THR 449 448 448 THR THR B . n 
B 1 450 GLY 450 449 449 GLY GLY B . n 
B 1 451 PRO 451 450 450 PRO PRO B . n 
B 1 452 ALA 452 451 451 ALA ALA B . n 
B 1 453 ALA 453 452 452 ALA ALA B . n 
B 1 454 PRO 454 453 453 PRO PRO B . n 
B 1 455 PRO 455 454 454 PRO PRO B . n 
B 1 456 ALA 456 455 455 ALA ALA B . n 
B 1 457 GLN 457 456 456 GLN GLN B . n 
B 1 458 ASN 458 457 457 ASN ASN B . n 
B 1 459 GLU 459 458 458 GLU GLU B . n 
B 1 460 LYS 460 459 459 LYS LYS B . n 
B 1 461 GLY 461 460 460 GLY GLY B . n 
B 1 462 LEU 462 461 461 LEU LEU B . n 
B 1 463 LYS 463 462 462 LYS LYS B . n 
B 1 464 ASP 464 463 463 ASP ASP B . n 
B 1 465 THR 465 464 464 THR THR B . n 
B 1 466 VAL 466 465 465 VAL VAL B . n 
B 1 467 LYS 467 466 466 LYS LYS B . n 
B 1 468 VAL 468 467 467 VAL VAL B . n 
B 1 469 PRO 469 468 468 PRO PRO B . n 
B 1 470 PRO 470 469 469 PRO PRO B . n 
B 1 471 GLY 471 470 470 GLY GLY B . n 
B 1 472 SER 472 471 471 SER SER B . n 
B 1 473 VAL 473 472 472 VAL VAL B . n 
B 1 474 THR 474 473 473 THR THR B . n 
B 1 475 ARG 475 474 474 ARG ARG B . n 
B 1 476 ILE 476 475 475 ILE ILE B . n 
B 1 477 ILE 477 476 476 ILE ILE B . n 
B 1 478 ALA 478 477 477 ALA ALA B . n 
B 1 479 THR 479 478 478 THR THR B . n 
B 1 480 PHE 480 479 479 PHE PHE B . n 
B 1 481 ALA 481 480 480 ALA ALA B . n 
B 1 482 PRO 482 481 481 PRO PRO B . n 
B 1 483 TYR 483 482 482 TYR TYR B . n 
B 1 484 SER 484 483 483 SER SER B . n 
B 1 485 GLY 485 484 484 GLY GLY B . n 
B 1 486 ARG 486 485 485 ARG ARG B . n 
B 1 487 TYR 487 486 486 TYR TYR B . n 
B 1 488 VAL 488 487 487 VAL VAL B . n 
B 1 489 TRP 489 488 488 TRP TRP B . n 
B 1 490 HIS 490 489 489 HIS HIS B . n 
B 1 491 CYS 491 490 490 CYS CYS B . n 
B 1 492 HIS 492 491 491 HIS HIS B . n 
B 1 493 ILE 493 492 492 ILE ILE B . n 
B 1 494 LEU 494 493 493 LEU LEU B . n 
B 1 495 GLU 495 494 494 GLU GLU B . n 
B 1 496 HIS 496 495 495 HIS HIS B . n 
B 1 497 GLU 497 496 496 GLU GLU B . n 
B 1 498 ASP 498 497 497 ASP ASP B . n 
B 1 499 TYR 499 498 498 TYR TYR B . n 
B 1 500 ASP 500 499 499 ASP ASP B . n 
B 1 501 MET 501 500 500 MET MET B . n 
B 1 502 MET 502 501 501 MET MET B . n 
B 1 503 ARG 503 502 502 ARG ARG B . n 
B 1 504 PRO 504 503 503 PRO PRO B . n 
B 1 505 LEU 505 504 504 LEU LEU B . n 
B 1 506 GLU 506 505 505 GLU GLU B . n 
B 1 507 VAL 507 506 506 VAL VAL B . n 
B 1 508 THR 508 507 507 THR THR B . n 
B 1 509 ASP 509 508 508 ASP ASP B . n 
B 1 510 ILE 510 509 509 ILE ILE B . n 
B 1 511 ARG 511 510 510 ARG ARG B . n 
B 1 512 HIS 512 511 511 HIS HIS B . n 
B 1 513 GLN 513 512 512 GLN GLN B . n 
B 1 514 GLU 514 513 ?   ?   ?   B . n 
B 1 515 PHE 515 514 ?   ?   ?   B . n 
B 1 516 GLU 516 515 ?   ?   ?   B . n 
B 1 517 ALA 517 516 ?   ?   ?   B . n 
B 1 518 TRP 518 517 ?   ?   ?   B . n 
B 1 519 ALA 519 518 ?   ?   ?   B . n 
B 1 520 ARG 520 519 ?   ?   ?   B . n 
B 1 521 THR 521 520 ?   ?   ?   B . n 
B 1 522 LYS 522 521 ?   ?   ?   B . n 
B 1 523 THR 523 522 ?   ?   ?   B . n 
B 1 524 HIS 524 523 ?   ?   ?   B . n 
B 1 525 LEU 525 524 ?   ?   ?   B . n 
B 1 526 ARG 526 525 ?   ?   ?   B . n 
B 1 527 ARG 527 526 ?   ?   ?   B . n 
B 1 528 GLY 528 527 ?   ?   ?   B . n 
B 1 529 SER 529 528 ?   ?   ?   B . n 
B 1 530 GLU 530 529 ?   ?   ?   B . n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        CU 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   CU 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
C  2 SO4 1   601 514  SO4 SO4 A . 
D  2 SO4 1   602 516  SO4 SO4 A . 
E  2 SO4 1   603 517  SO4 SO4 A . 
F  2 SO4 1   604 518  SO4 SO4 A . 
G  2 SO4 1   605 519  SO4 SO4 A . 
H  2 SO4 1   606 520  SO4 SO4 A . 
I  3 CU  1   607 524  CU  CU  A . 
J  2 SO4 1   608 525  SO4 SO4 A . 
K  2 SO4 1   609 526  SO4 SO4 A . 
L  2 SO4 1   610 528  SO4 SO4 A . 
M  2 SO4 1   611 529  SO4 SO4 A . 
N  2 SO4 1   612 530  SO4 SO4 A . 
O  3 CU  1   613 611  CU  CU  A . 
P  3 CU  1   614 612  CU  CU  A . 
Q  3 CU  1   615 613  CU  CU  A . 
R  2 SO4 1   616 518  SO4 SO4 A . 
S  2 SO4 1   601 514  SO4 SO4 B . 
T  2 SO4 1   602 516  SO4 SO4 B . 
U  2 SO4 1   603 517  SO4 SO4 B . 
V  2 SO4 1   604 519  SO4 SO4 B . 
W  2 SO4 1   605 520  SO4 SO4 B . 
X  3 CU  1   606 524  CU  CU  B . 
Y  2 SO4 1   607 525  SO4 SO4 B . 
Z  2 SO4 1   608 526  SO4 SO4 B . 
AA 2 SO4 1   609 527  SO4 SO4 B . 
BA 2 SO4 1   610 528  SO4 SO4 B . 
CA 2 SO4 1   611 529  SO4 SO4 B . 
DA 2 SO4 1   612 530  SO4 SO4 B . 
EA 3 CU  1   613 611  CU  CU  B . 
FA 3 CU  1   614 612  CU  CU  B . 
GA 3 CU  1   615 613  CU  CU  B . 
HA 4 HOH 1   701 682  HOH HOH A . 
HA 4 HOH 2   702 1909 HOH HOH A . 
HA 4 HOH 3   703 2127 HOH HOH A . 
HA 4 HOH 4   704 807  HOH HOH A . 
HA 4 HOH 5   705 747  HOH HOH A . 
HA 4 HOH 6   706 2609 HOH HOH A . 
HA 4 HOH 7   707 1048 HOH HOH A . 
HA 4 HOH 8   708 2084 HOH HOH A . 
HA 4 HOH 9   709 1714 HOH HOH A . 
HA 4 HOH 10  710 3384 HOH HOH A . 
HA 4 HOH 11  711 3710 HOH HOH A . 
HA 4 HOH 12  712 3543 HOH HOH A . 
HA 4 HOH 13  713 3679 HOH HOH A . 
HA 4 HOH 14  714 772  HOH HOH A . 
HA 4 HOH 15  715 2078 HOH HOH A . 
HA 4 HOH 16  716 888  HOH HOH A . 
HA 4 HOH 17  717 686  HOH HOH A . 
HA 4 HOH 18  718 566  HOH HOH A . 
HA 4 HOH 19  719 573  HOH HOH A . 
HA 4 HOH 20  720 762  HOH HOH A . 
HA 4 HOH 21  721 1675 HOH HOH A . 
HA 4 HOH 22  722 957  HOH HOH A . 
HA 4 HOH 23  723 932  HOH HOH A . 
HA 4 HOH 24  724 592  HOH HOH A . 
HA 4 HOH 25  725 597  HOH HOH A . 
HA 4 HOH 26  726 3440 HOH HOH A . 
HA 4 HOH 27  727 3635 HOH HOH A . 
HA 4 HOH 28  728 652  HOH HOH A . 
HA 4 HOH 29  729 1516 HOH HOH A . 
HA 4 HOH 30  730 852  HOH HOH A . 
HA 4 HOH 31  731 557  HOH HOH A . 
HA 4 HOH 32  732 882  HOH HOH A . 
HA 4 HOH 33  733 612  HOH HOH A . 
HA 4 HOH 34  734 3072 HOH HOH A . 
HA 4 HOH 35  735 2311 HOH HOH A . 
HA 4 HOH 36  736 1107 HOH HOH A . 
HA 4 HOH 37  737 728  HOH HOH A . 
HA 4 HOH 38  738 670  HOH HOH A . 
HA 4 HOH 39  739 879  HOH HOH A . 
HA 4 HOH 40  740 2788 HOH HOH A . 
HA 4 HOH 41  741 663  HOH HOH A . 
HA 4 HOH 42  742 732  HOH HOH A . 
HA 4 HOH 43  743 795  HOH HOH A . 
HA 4 HOH 44  744 3725 HOH HOH A . 
HA 4 HOH 45  745 1503 HOH HOH A . 
HA 4 HOH 46  746 1179 HOH HOH A . 
HA 4 HOH 47  747 1010 HOH HOH A . 
HA 4 HOH 48  748 643  HOH HOH A . 
HA 4 HOH 49  749 539  HOH HOH A . 
HA 4 HOH 50  750 621  HOH HOH A . 
HA 4 HOH 51  751 570  HOH HOH A . 
HA 4 HOH 52  752 1300 HOH HOH A . 
HA 4 HOH 53  753 959  HOH HOH A . 
HA 4 HOH 54  754 742  HOH HOH A . 
HA 4 HOH 55  755 547  HOH HOH A . 
HA 4 HOH 56  756 666  HOH HOH A . 
HA 4 HOH 57  757 1449 HOH HOH A . 
HA 4 HOH 58  758 1786 HOH HOH A . 
HA 4 HOH 59  759 3451 HOH HOH A . 
HA 4 HOH 60  760 604  HOH HOH A . 
HA 4 HOH 61  761 877  HOH HOH A . 
HA 4 HOH 62  762 1695 HOH HOH A . 
HA 4 HOH 63  763 660  HOH HOH A . 
HA 4 HOH 64  764 1021 HOH HOH A . 
HA 4 HOH 65  765 1596 HOH HOH A . 
HA 4 HOH 66  766 538  HOH HOH A . 
HA 4 HOH 67  767 783  HOH HOH A . 
HA 4 HOH 68  768 620  HOH HOH A . 
HA 4 HOH 69  769 656  HOH HOH A . 
HA 4 HOH 70  770 608  HOH HOH A . 
HA 4 HOH 71  771 1380 HOH HOH A . 
HA 4 HOH 72  772 531  HOH HOH A . 
HA 4 HOH 73  773 540  HOH HOH A . 
HA 4 HOH 74  774 899  HOH HOH A . 
HA 4 HOH 75  775 609  HOH HOH A . 
HA 4 HOH 76  776 565  HOH HOH A . 
HA 4 HOH 77  777 1828 HOH HOH A . 
HA 4 HOH 78  778 942  HOH HOH A . 
HA 4 HOH 79  779 579  HOH HOH A . 
HA 4 HOH 80  780 1304 HOH HOH A . 
HA 4 HOH 81  781 954  HOH HOH A . 
HA 4 HOH 82  782 2079 HOH HOH A . 
HA 4 HOH 83  783 640  HOH HOH A . 
HA 4 HOH 84  784 2775 HOH HOH A . 
HA 4 HOH 85  785 3424 HOH HOH A . 
HA 4 HOH 86  786 563  HOH HOH A . 
HA 4 HOH 87  787 1110 HOH HOH A . 
HA 4 HOH 88  788 827  HOH HOH A . 
HA 4 HOH 89  789 787  HOH HOH A . 
HA 4 HOH 90  790 605  HOH HOH A . 
HA 4 HOH 91  791 2699 HOH HOH A . 
HA 4 HOH 92  792 606  HOH HOH A . 
HA 4 HOH 93  793 556  HOH HOH A . 
HA 4 HOH 94  794 2900 HOH HOH A . 
HA 4 HOH 95  795 1210 HOH HOH A . 
HA 4 HOH 96  796 590  HOH HOH A . 
HA 4 HOH 97  797 2731 HOH HOH A . 
HA 4 HOH 98  798 840  HOH HOH A . 
HA 4 HOH 99  799 1752 HOH HOH A . 
HA 4 HOH 100 800 669  HOH HOH A . 
HA 4 HOH 101 801 1395 HOH HOH A . 
HA 4 HOH 102 802 832  HOH HOH A . 
HA 4 HOH 103 803 1375 HOH HOH A . 
HA 4 HOH 104 804 809  HOH HOH A . 
HA 4 HOH 105 805 1309 HOH HOH A . 
HA 4 HOH 106 806 947  HOH HOH A . 
HA 4 HOH 107 807 1046 HOH HOH A . 
HA 4 HOH 108 808 1003 HOH HOH A . 
HA 4 HOH 109 809 1710 HOH HOH A . 
HA 4 HOH 110 810 1123 HOH HOH A . 
HA 4 HOH 111 811 596  HOH HOH A . 
HA 4 HOH 112 812 642  HOH HOH A . 
HA 4 HOH 113 813 2668 HOH HOH A . 
HA 4 HOH 114 814 869  HOH HOH A . 
HA 4 HOH 115 815 2643 HOH HOH A . 
HA 4 HOH 116 816 785  HOH HOH A . 
HA 4 HOH 117 817 844  HOH HOH A . 
HA 4 HOH 118 818 778  HOH HOH A . 
HA 4 HOH 119 819 701  HOH HOH A . 
HA 4 HOH 120 820 2859 HOH HOH A . 
HA 4 HOH 121 821 1970 HOH HOH A . 
HA 4 HOH 122 822 3651 HOH HOH A . 
HA 4 HOH 123 823 886  HOH HOH A . 
HA 4 HOH 124 824 560  HOH HOH A . 
HA 4 HOH 125 825 766  HOH HOH A . 
HA 4 HOH 126 826 1313 HOH HOH A . 
HA 4 HOH 127 827 737  HOH HOH A . 
HA 4 HOH 128 828 759  HOH HOH A . 
HA 4 HOH 129 829 1170 HOH HOH A . 
HA 4 HOH 130 830 1278 HOH HOH A . 
HA 4 HOH 131 831 650  HOH HOH A . 
HA 4 HOH 132 832 2584 HOH HOH A . 
HA 4 HOH 133 833 901  HOH HOH A . 
HA 4 HOH 134 834 699  HOH HOH A . 
HA 4 HOH 135 835 1735 HOH HOH A . 
HA 4 HOH 136 836 1103 HOH HOH A . 
HA 4 HOH 137 837 706  HOH HOH A . 
HA 4 HOH 138 838 2570 HOH HOH A . 
HA 4 HOH 139 839 1116 HOH HOH A . 
HA 4 HOH 140 840 1347 HOH HOH A . 
HA 4 HOH 141 841 3722 HOH HOH A . 
HA 4 HOH 142 842 585  HOH HOH A . 
HA 4 HOH 143 843 1230 HOH HOH A . 
HA 4 HOH 144 844 1052 HOH HOH A . 
HA 4 HOH 145 845 3600 HOH HOH A . 
HA 4 HOH 146 846 1205 HOH HOH A . 
HA 4 HOH 147 847 639  HOH HOH A . 
HA 4 HOH 148 848 2938 HOH HOH A . 
HA 4 HOH 149 849 773  HOH HOH A . 
HA 4 HOH 150 850 2581 HOH HOH A . 
HA 4 HOH 151 851 3158 HOH HOH A . 
HA 4 HOH 152 852 971  HOH HOH A . 
HA 4 HOH 153 853 949  HOH HOH A . 
HA 4 HOH 154 854 1090 HOH HOH A . 
HA 4 HOH 155 855 1901 HOH HOH A . 
HA 4 HOH 156 856 868  HOH HOH A . 
HA 4 HOH 157 857 3707 HOH HOH A . 
HA 4 HOH 158 858 2517 HOH HOH A . 
HA 4 HOH 159 859 655  HOH HOH A . 
HA 4 HOH 160 860 2857 HOH HOH A . 
HA 4 HOH 161 861 1483 HOH HOH A . 
HA 4 HOH 162 862 589  HOH HOH A . 
HA 4 HOH 163 863 963  HOH HOH A . 
HA 4 HOH 164 864 854  HOH HOH A . 
HA 4 HOH 165 865 891  HOH HOH A . 
HA 4 HOH 166 866 677  HOH HOH A . 
HA 4 HOH 167 867 1745 HOH HOH A . 
HA 4 HOH 168 868 3477 HOH HOH A . 
HA 4 HOH 169 869 860  HOH HOH A . 
HA 4 HOH 170 870 1363 HOH HOH A . 
HA 4 HOH 171 871 2058 HOH HOH A . 
HA 4 HOH 172 872 683  HOH HOH A . 
HA 4 HOH 173 873 1232 HOH HOH A . 
HA 4 HOH 174 874 839  HOH HOH A . 
HA 4 HOH 175 875 1894 HOH HOH A . 
HA 4 HOH 176 876 849  HOH HOH A . 
HA 4 HOH 177 877 3916 HOH HOH A . 
HA 4 HOH 178 878 3145 HOH HOH A . 
HA 4 HOH 179 879 707  HOH HOH A . 
HA 4 HOH 180 880 824  HOH HOH A . 
HA 4 HOH 181 881 1132 HOH HOH A . 
HA 4 HOH 182 882 1195 HOH HOH A . 
HA 4 HOH 183 883 3167 HOH HOH A . 
HA 4 HOH 184 884 2052 HOH HOH A . 
HA 4 HOH 185 885 965  HOH HOH A . 
HA 4 HOH 186 886 687  HOH HOH A . 
HA 4 HOH 187 887 3697 HOH HOH A . 
HA 4 HOH 188 888 842  HOH HOH A . 
HA 4 HOH 189 889 3369 HOH HOH A . 
HA 4 HOH 190 890 1840 HOH HOH A . 
HA 4 HOH 191 891 3482 HOH HOH A . 
HA 4 HOH 192 892 2712 HOH HOH A . 
HA 4 HOH 193 893 616  HOH HOH A . 
HA 4 HOH 194 894 1167 HOH HOH A . 
HA 4 HOH 195 895 618  HOH HOH A . 
HA 4 HOH 196 896 1803 HOH HOH A . 
HA 4 HOH 197 897 1385 HOH HOH A . 
HA 4 HOH 198 898 3448 HOH HOH A . 
HA 4 HOH 199 899 1191 HOH HOH A . 
HA 4 HOH 200 900 1408 HOH HOH A . 
HA 4 HOH 201 901 1328 HOH HOH A . 
HA 4 HOH 202 902 1093 HOH HOH A . 
HA 4 HOH 203 903 702  HOH HOH A . 
HA 4 HOH 204 904 812  HOH HOH A . 
HA 4 HOH 205 905 4192 HOH HOH A . 
HA 4 HOH 206 906 2642 HOH HOH A . 
HA 4 HOH 207 907 1541 HOH HOH A . 
HA 4 HOH 208 908 3063 HOH HOH A . 
HA 4 HOH 209 909 3625 HOH HOH A . 
HA 4 HOH 210 910 3511 HOH HOH A . 
HA 4 HOH 211 911 1022 HOH HOH A . 
HA 4 HOH 212 912 1806 HOH HOH A . 
HA 4 HOH 213 913 2716 HOH HOH A . 
HA 4 HOH 214 914 4199 HOH HOH A . 
HA 4 HOH 215 915 2649 HOH HOH A . 
HA 4 HOH 216 916 1320 HOH HOH A . 
HA 4 HOH 217 917 2904 HOH HOH A . 
HA 4 HOH 218 918 1204 HOH HOH A . 
HA 4 HOH 219 919 1354 HOH HOH A . 
HA 4 HOH 220 920 1532 HOH HOH A . 
HA 4 HOH 221 921 1049 HOH HOH A . 
HA 4 HOH 222 922 3715 HOH HOH A . 
HA 4 HOH 223 923 2433 HOH HOH A . 
HA 4 HOH 224 924 799  HOH HOH A . 
HA 4 HOH 225 925 1125 HOH HOH A . 
HA 4 HOH 226 926 1578 HOH HOH A . 
HA 4 HOH 227 927 1368 HOH HOH A . 
HA 4 HOH 228 928 2864 HOH HOH A . 
HA 4 HOH 229 929 1085 HOH HOH A . 
HA 4 HOH 230 930 1247 HOH HOH A . 
HA 4 HOH 231 931 3449 HOH HOH A . 
HA 4 HOH 232 932 1336 HOH HOH A . 
HA 4 HOH 233 933 3168 HOH HOH A . 
HA 4 HOH 234 934 1409 HOH HOH A . 
HA 4 HOH 235 935 1859 HOH HOH A . 
HA 4 HOH 236 936 2549 HOH HOH A . 
HA 4 HOH 237 937 2852 HOH HOH A . 
HA 4 HOH 238 938 1340 HOH HOH A . 
HA 4 HOH 239 939 2343 HOH HOH A . 
HA 4 HOH 240 940 3629 HOH HOH A . 
HA 4 HOH 241 941 2913 HOH HOH A . 
HA 4 HOH 242 942 1667 HOH HOH A . 
HA 4 HOH 243 943 1973 HOH HOH A . 
HA 4 HOH 244 944 1007 HOH HOH A . 
HA 4 HOH 245 945 3068 HOH HOH A . 
HA 4 HOH 246 946 4168 HOH HOH A . 
HA 4 HOH 247 947 2348 HOH HOH A . 
HA 4 HOH 248 948 3540 HOH HOH A . 
HA 4 HOH 249 949 1876 HOH HOH A . 
HA 4 HOH 250 950 1704 HOH HOH A . 
HA 4 HOH 251 951 1914 HOH HOH A . 
HA 4 HOH 252 952 3575 HOH HOH A . 
HA 4 HOH 253 953 1177 HOH HOH A . 
HA 4 HOH 254 954 3165 HOH HOH A . 
HA 4 HOH 255 955 1574 HOH HOH A . 
HA 4 HOH 256 956 1196 HOH HOH A . 
HA 4 HOH 257 957 2521 HOH HOH A . 
HA 4 HOH 258 958 1276 HOH HOH A . 
HA 4 HOH 259 959 1092 HOH HOH A . 
HA 4 HOH 260 960 2981 HOH HOH A . 
HA 4 HOH 261 961 1158 HOH HOH A . 
HA 4 HOH 262 962 4190 HOH HOH A . 
HA 4 HOH 263 963 1820 HOH HOH A . 
HA 4 HOH 264 964 1011 HOH HOH A . 
HA 4 HOH 265 965 1993 HOH HOH A . 
HA 4 HOH 266 966 3520 HOH HOH A . 
HA 4 HOH 267 967 3431 HOH HOH A . 
HA 4 HOH 268 968 1419 HOH HOH A . 
HA 4 HOH 269 969 1153 HOH HOH A . 
HA 4 HOH 270 970 3601 HOH HOH A . 
HA 4 HOH 271 971 2305 HOH HOH A . 
HA 4 HOH 272 972 2672 HOH HOH A . 
HA 4 HOH 273 973 3281 HOH HOH A . 
HA 4 HOH 274 974 1680 HOH HOH A . 
HA 4 HOH 275 975 2183 HOH HOH A . 
HA 4 HOH 276 976 727  HOH HOH A . 
HA 4 HOH 277 977 3196 HOH HOH A . 
HA 4 HOH 278 978 3997 HOH HOH A . 
HA 4 HOH 279 979 1552 HOH HOH A . 
HA 4 HOH 280 980 2294 HOH HOH A . 
HA 4 HOH 281 981 2861 HOH HOH A . 
HA 4 HOH 282 982 1725 HOH HOH A . 
HA 4 HOH 283 983 3695 HOH HOH A . 
HA 4 HOH 284 984 1716 HOH HOH A . 
HA 4 HOH 285 985 1269 HOH HOH A . 
HA 4 HOH 286 986 3473 HOH HOH A . 
HA 4 HOH 287 987 986  HOH HOH A . 
HA 4 HOH 288 988 3557 HOH HOH A . 
IA 4 HOH 1   701 2540 HOH HOH B . 
IA 4 HOH 2   702 3908 HOH HOH B . 
IA 4 HOH 3   703 644  HOH HOH B . 
IA 4 HOH 4   704 1506 HOH HOH B . 
IA 4 HOH 5   705 1415 HOH HOH B . 
IA 4 HOH 6   706 859  HOH HOH B . 
IA 4 HOH 7   707 1731 HOH HOH B . 
IA 4 HOH 8   708 924  HOH HOH B . 
IA 4 HOH 9   709 1203 HOH HOH B . 
IA 4 HOH 10  710 637  HOH HOH B . 
IA 4 HOH 11  711 1665 HOH HOH B . 
IA 4 HOH 12  712 679  HOH HOH B . 
IA 4 HOH 13  713 1390 HOH HOH B . 
IA 4 HOH 14  714 1991 HOH HOH B . 
IA 4 HOH 15  715 3691 HOH HOH B . 
IA 4 HOH 16  716 1323 HOH HOH B . 
IA 4 HOH 17  717 813  HOH HOH B . 
IA 4 HOH 18  718 902  HOH HOH B . 
IA 4 HOH 19  719 1145 HOH HOH B . 
IA 4 HOH 20  720 676  HOH HOH B . 
IA 4 HOH 21  721 685  HOH HOH B . 
IA 4 HOH 22  722 847  HOH HOH B . 
IA 4 HOH 23  723 580  HOH HOH B . 
IA 4 HOH 24  724 624  HOH HOH B . 
IA 4 HOH 25  725 1365 HOH HOH B . 
IA 4 HOH 26  726 1254 HOH HOH B . 
IA 4 HOH 27  727 723  HOH HOH B . 
IA 4 HOH 28  728 1679 HOH HOH B . 
IA 4 HOH 29  729 922  HOH HOH B . 
IA 4 HOH 30  730 1155 HOH HOH B . 
IA 4 HOH 31  731 716  HOH HOH B . 
IA 4 HOH 32  732 2871 HOH HOH B . 
IA 4 HOH 33  733 1242 HOH HOH B . 
IA 4 HOH 34  734 619  HOH HOH B . 
IA 4 HOH 35  735 567  HOH HOH B . 
IA 4 HOH 36  736 3959 HOH HOH B . 
IA 4 HOH 37  737 562  HOH HOH B . 
IA 4 HOH 38  738 1262 HOH HOH B . 
IA 4 HOH 39  739 3325 HOH HOH B . 
IA 4 HOH 40  740 1026 HOH HOH B . 
IA 4 HOH 41  741 696  HOH HOH B . 
IA 4 HOH 42  742 541  HOH HOH B . 
IA 4 HOH 43  743 598  HOH HOH B . 
IA 4 HOH 44  744 720  HOH HOH B . 
IA 4 HOH 45  745 3925 HOH HOH B . 
IA 4 HOH 46  746 2916 HOH HOH B . 
IA 4 HOH 47  747 1295 HOH HOH B . 
IA 4 HOH 48  748 1294 HOH HOH B . 
IA 4 HOH 49  749 710  HOH HOH B . 
IA 4 HOH 50  750 632  HOH HOH B . 
IA 4 HOH 51  751 1615 HOH HOH B . 
IA 4 HOH 52  752 1235 HOH HOH B . 
IA 4 HOH 53  753 2335 HOH HOH B . 
IA 4 HOH 54  754 843  HOH HOH B . 
IA 4 HOH 55  755 1905 HOH HOH B . 
IA 4 HOH 56  756 881  HOH HOH B . 
IA 4 HOH 57  757 587  HOH HOH B . 
IA 4 HOH 58  758 724  HOH HOH B . 
IA 4 HOH 59  759 1604 HOH HOH B . 
IA 4 HOH 60  760 979  HOH HOH B . 
IA 4 HOH 61  761 941  HOH HOH B . 
IA 4 HOH 62  762 1339 HOH HOH B . 
IA 4 HOH 63  763 542  HOH HOH B . 
IA 4 HOH 64  764 614  HOH HOH B . 
IA 4 HOH 65  765 1316 HOH HOH B . 
IA 4 HOH 66  766 610  HOH HOH B . 
IA 4 HOH 67  767 581  HOH HOH B . 
IA 4 HOH 68  768 1575 HOH HOH B . 
IA 4 HOH 69  769 622  HOH HOH B . 
IA 4 HOH 70  770 602  HOH HOH B . 
IA 4 HOH 71  771 1394 HOH HOH B . 
IA 4 HOH 72  772 623  HOH HOH B . 
IA 4 HOH 73  773 1240 HOH HOH B . 
IA 4 HOH 74  774 2785 HOH HOH B . 
IA 4 HOH 75  775 1942 HOH HOH B . 
IA 4 HOH 76  776 698  HOH HOH B . 
IA 4 HOH 77  777 545  HOH HOH B . 
IA 4 HOH 78  778 648  HOH HOH B . 
IA 4 HOH 79  779 866  HOH HOH B . 
IA 4 HOH 80  780 625  HOH HOH B . 
IA 4 HOH 81  781 2088 HOH HOH B . 
IA 4 HOH 82  782 3046 HOH HOH B . 
IA 4 HOH 83  783 559  HOH HOH B . 
IA 4 HOH 84  784 1112 HOH HOH B . 
IA 4 HOH 85  785 591  HOH HOH B . 
IA 4 HOH 86  786 575  HOH HOH B . 
IA 4 HOH 87  787 576  HOH HOH B . 
IA 4 HOH 88  788 718  HOH HOH B . 
IA 4 HOH 89  789 1131 HOH HOH B . 
IA 4 HOH 90  790 601  HOH HOH B . 
IA 4 HOH 91  791 1130 HOH HOH B . 
IA 4 HOH 92  792 779  HOH HOH B . 
IA 4 HOH 93  793 2143 HOH HOH B . 
IA 4 HOH 94  794 1239 HOH HOH B . 
IA 4 HOH 95  795 1388 HOH HOH B . 
IA 4 HOH 96  796 554  HOH HOH B . 
IA 4 HOH 97  797 703  HOH HOH B . 
IA 4 HOH 98  798 611  HOH HOH B . 
IA 4 HOH 99  799 2243 HOH HOH B . 
IA 4 HOH 100 800 553  HOH HOH B . 
IA 4 HOH 101 801 733  HOH HOH B . 
IA 4 HOH 102 802 583  HOH HOH B . 
IA 4 HOH 103 803 1126 HOH HOH B . 
IA 4 HOH 104 804 3499 HOH HOH B . 
IA 4 HOH 105 805 1801 HOH HOH B . 
IA 4 HOH 106 806 1070 HOH HOH B . 
IA 4 HOH 107 807 964  HOH HOH B . 
IA 4 HOH 108 808 1219 HOH HOH B . 
IA 4 HOH 109 809 2860 HOH HOH B . 
IA 4 HOH 110 810 1000 HOH HOH B . 
IA 4 HOH 111 811 878  HOH HOH B . 
IA 4 HOH 112 812 1917 HOH HOH B . 
IA 4 HOH 113 813 709  HOH HOH B . 
IA 4 HOH 114 814 729  HOH HOH B . 
IA 4 HOH 115 815 975  HOH HOH B . 
IA 4 HOH 116 816 1163 HOH HOH B . 
IA 4 HOH 117 817 1297 HOH HOH B . 
IA 4 HOH 118 818 987  HOH HOH B . 
IA 4 HOH 119 819 599  HOH HOH B . 
IA 4 HOH 120 820 721  HOH HOH B . 
IA 4 HOH 121 821 1808 HOH HOH B . 
IA 4 HOH 122 822 994  HOH HOH B . 
IA 4 HOH 123 823 4008 HOH HOH B . 
IA 4 HOH 124 824 952  HOH HOH B . 
IA 4 HOH 125 825 3659 HOH HOH B . 
IA 4 HOH 126 826 760  HOH HOH B . 
IA 4 HOH 127 827 1188 HOH HOH B . 
IA 4 HOH 128 828 1053 HOH HOH B . 
IA 4 HOH 129 829 784  HOH HOH B . 
IA 4 HOH 130 830 821  HOH HOH B . 
IA 4 HOH 131 831 1144 HOH HOH B . 
IA 4 HOH 132 832 1350 HOH HOH B . 
IA 4 HOH 133 833 978  HOH HOH B . 
IA 4 HOH 134 834 1729 HOH HOH B . 
IA 4 HOH 135 835 1558 HOH HOH B . 
IA 4 HOH 136 836 3510 HOH HOH B . 
IA 4 HOH 137 837 582  HOH HOH B . 
IA 4 HOH 138 838 775  HOH HOH B . 
IA 4 HOH 139 839 1737 HOH HOH B . 
IA 4 HOH 140 840 2010 HOH HOH B . 
IA 4 HOH 141 841 770  HOH HOH B . 
IA 4 HOH 142 842 749  HOH HOH B . 
IA 4 HOH 143 843 823  HOH HOH B . 
IA 4 HOH 144 844 646  HOH HOH B . 
IA 4 HOH 145 845 1301 HOH HOH B . 
IA 4 HOH 146 846 3151 HOH HOH B . 
IA 4 HOH 147 847 665  HOH HOH B . 
IA 4 HOH 148 848 863  HOH HOH B . 
IA 4 HOH 149 849 1250 HOH HOH B . 
IA 4 HOH 150 850 792  HOH HOH B . 
IA 4 HOH 151 851 830  HOH HOH B . 
IA 4 HOH 152 852 837  HOH HOH B . 
IA 4 HOH 153 853 960  HOH HOH B . 
IA 4 HOH 154 854 806  HOH HOH B . 
IA 4 HOH 155 855 1367 HOH HOH B . 
IA 4 HOH 156 856 1226 HOH HOH B . 
IA 4 HOH 157 857 3650 HOH HOH B . 
IA 4 HOH 158 858 1141 HOH HOH B . 
IA 4 HOH 159 859 1420 HOH HOH B . 
IA 4 HOH 160 860 2912 HOH HOH B . 
IA 4 HOH 161 861 3964 HOH HOH B . 
IA 4 HOH 162 862 763  HOH HOH B . 
IA 4 HOH 163 863 1268 HOH HOH B . 
IA 4 HOH 164 864 1895 HOH HOH B . 
IA 4 HOH 165 865 1568 HOH HOH B . 
IA 4 HOH 166 866 3944 HOH HOH B . 
IA 4 HOH 167 867 1008 HOH HOH B . 
IA 4 HOH 168 868 671  HOH HOH B . 
IA 4 HOH 169 869 1228 HOH HOH B . 
IA 4 HOH 170 870 1096 HOH HOH B . 
IA 4 HOH 171 871 805  HOH HOH B . 
IA 4 HOH 172 872 834  HOH HOH B . 
IA 4 HOH 173 873 1233 HOH HOH B . 
IA 4 HOH 174 874 1274 HOH HOH B . 
IA 4 HOH 175 875 948  HOH HOH B . 
IA 4 HOH 176 876 588  HOH HOH B . 
IA 4 HOH 177 877 629  HOH HOH B . 
IA 4 HOH 178 878 1209 HOH HOH B . 
IA 4 HOH 179 879 704  HOH HOH B . 
IA 4 HOH 180 880 1621 HOH HOH B . 
IA 4 HOH 181 881 1524 HOH HOH B . 
IA 4 HOH 182 882 2729 HOH HOH B . 
IA 4 HOH 183 883 2841 HOH HOH B . 
IA 4 HOH 184 884 634  HOH HOH B . 
IA 4 HOH 185 885 755  HOH HOH B . 
IA 4 HOH 186 886 1439 HOH HOH B . 
IA 4 HOH 187 887 2853 HOH HOH B . 
IA 4 HOH 188 888 3497 HOH HOH B . 
IA 4 HOH 189 889 1893 HOH HOH B . 
IA 4 HOH 190 890 814  HOH HOH B . 
IA 4 HOH 191 891 1266 HOH HOH B . 
IA 4 HOH 192 892 3996 HOH HOH B . 
IA 4 HOH 193 893 2708 HOH HOH B . 
IA 4 HOH 194 894 1397 HOH HOH B . 
IA 4 HOH 195 895 750  HOH HOH B . 
IA 4 HOH 196 896 1979 HOH HOH B . 
IA 4 HOH 197 897 1639 HOH HOH B . 
IA 4 HOH 198 898 1732 HOH HOH B . 
IA 4 HOH 199 899 2656 HOH HOH B . 
IA 4 HOH 200 900 1694 HOH HOH B . 
IA 4 HOH 201 901 3454 HOH HOH B . 
IA 4 HOH 202 902 3094 HOH HOH B . 
IA 4 HOH 203 903 1224 HOH HOH B . 
IA 4 HOH 204 904 905  HOH HOH B . 
IA 4 HOH 205 905 2049 HOH HOH B . 
IA 4 HOH 206 906 925  HOH HOH B . 
IA 4 HOH 207 907 1083 HOH HOH B . 
IA 4 HOH 208 908 2244 HOH HOH B . 
IA 4 HOH 209 909 874  HOH HOH B . 
IA 4 HOH 210 910 2167 HOH HOH B . 
IA 4 HOH 211 911 3809 HOH HOH B . 
IA 4 HOH 212 912 1088 HOH HOH B . 
IA 4 HOH 213 913 1466 HOH HOH B . 
IA 4 HOH 214 914 3169 HOH HOH B . 
IA 4 HOH 215 915 2820 HOH HOH B . 
IA 4 HOH 216 916 1860 HOH HOH B . 
IA 4 HOH 217 917 2273 HOH HOH B . 
IA 4 HOH 218 918 3926 HOH HOH B . 
IA 4 HOH 219 919 1087 HOH HOH B . 
IA 4 HOH 220 920 2709 HOH HOH B . 
IA 4 HOH 221 921 1104 HOH HOH B . 
IA 4 HOH 222 922 3991 HOH HOH B . 
IA 4 HOH 223 923 1004 HOH HOH B . 
IA 4 HOH 224 924 2816 HOH HOH B . 
IA 4 HOH 225 925 1427 HOH HOH B . 
IA 4 HOH 226 926 985  HOH HOH B . 
IA 4 HOH 227 927 1599 HOH HOH B . 
IA 4 HOH 228 928 3956 HOH HOH B . 
IA 4 HOH 229 929 1357 HOH HOH B . 
IA 4 HOH 230 930 3531 HOH HOH B . 
IA 4 HOH 231 931 2735 HOH HOH B . 
IA 4 HOH 232 932 1095 HOH HOH B . 
IA 4 HOH 233 933 1674 HOH HOH B . 
IA 4 HOH 234 934 1482 HOH HOH B . 
IA 4 HOH 235 935 861  HOH HOH B . 
IA 4 HOH 236 936 2152 HOH HOH B . 
IA 4 HOH 237 937 1748 HOH HOH B . 
IA 4 HOH 238 938 3755 HOH HOH B . 
IA 4 HOH 239 939 1238 HOH HOH B . 
IA 4 HOH 240 940 1148 HOH HOH B . 
IA 4 HOH 241 941 2693 HOH HOH B . 
IA 4 HOH 242 942 1101 HOH HOH B . 
IA 4 HOH 243 943 3328 HOH HOH B . 
IA 4 HOH 244 944 2601 HOH HOH B . 
IA 4 HOH 245 945 551  HOH HOH B . 
IA 4 HOH 246 946 1115 HOH HOH B . 
IA 4 HOH 247 947 2901 HOH HOH B . 
IA 4 HOH 248 948 1446 HOH HOH B . 
IA 4 HOH 249 949 2568 HOH HOH B . 
IA 4 HOH 250 950 1623 HOH HOH B . 
IA 4 HOH 251 951 1192 HOH HOH B . 
IA 4 HOH 252 952 1120 HOH HOH B . 
IA 4 HOH 253 953 1658 HOH HOH B . 
IA 4 HOH 254 954 1933 HOH HOH B . 
IA 4 HOH 255 955 945  HOH HOH B . 
IA 4 HOH 256 956 836  HOH HOH B . 
IA 4 HOH 257 957 2331 HOH HOH B . 
IA 4 HOH 258 958 810  HOH HOH B . 
IA 4 HOH 259 959 4151 HOH HOH B . 
IA 4 HOH 260 960 1972 HOH HOH B . 
IA 4 HOH 261 961 999  HOH HOH B . 
IA 4 HOH 262 962 2168 HOH HOH B . 
IA 4 HOH 263 963 3516 HOH HOH B . 
IA 4 HOH 264 964 2608 HOH HOH B . 
IA 4 HOH 265 965 3336 HOH HOH B . 
IA 4 HOH 266 966 2342 HOH HOH B . 
IA 4 HOH 267 967 2095 HOH HOH B . 
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX         ? ? ? 1.21rc1_5134 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? 'PROTEUM PLUS' ? ? ? .            2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? 'PROTEUM PLUS' ? ? ? .            3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER         ? ? ? .            4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.000 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  120.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BD5 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     94.800 
_cell.length_a_esd                 ? 
_cell.length_b                     94.800 
_cell.length_b_esd                 ? 
_cell.length_c                     271.658 
_cell.length_c_esd                 ? 
_cell.volume                       2114315.557 
_cell.volume_esd                   ? 
_cell.Z_PDB                        12 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BD5 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                170 
_symmetry.space_group_name_Hall            'P 65' 
_symmetry.space_group_name_H-M             'P 65' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BD5 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.87 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          57.08 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              ? 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'2 M ammonium sulfate as the reservoir and the drop was composed of a 3:1 ratio of protein (5 mg mL-1): reservoir solution' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            293 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     CMOS 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'BRUKER PHOTON 100' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2023-10-17 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   1.5406 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      'ROTATING ANODE' 
_diffrn_source.target                      ? 
_diffrn_source.type                        'BRUKER X8 PROTEUM' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        1.5406 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   ? 
_diffrn_source.pdbx_synchrotron_site       ? 
# 
_reflns.B_iso_Wilson_estimate                          22.45 
_reflns.entry_id                                       9BD5 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              2.7 
_reflns.d_resolution_low                               33.2 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     36830 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           97.67 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                3.75 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          9.1 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                ? 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   ? 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              ? 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                .112 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    2.7 
_reflns_shell.d_res_low                                     2.8 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           ? 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3808 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               ? 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  ? 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  .35 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               23.47 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BD5 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            2.70 
_refine.ls_d_res_low                             23.70 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     36830 
_refine.ls_number_reflns_R_free                  1846 
_refine.ls_number_reflns_R_work                  34984 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    97.67 
_refine.ls_percent_reflns_R_free                 5.01 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1915 
_refine.ls_R_factor_R_free                       0.2322 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1894 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.34 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 23.4790 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2608 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       2.70 
_refine_hist.d_res_low                        23.70 
_refine_hist.number_atoms_solvent             555 
_refine_hist.number_atoms_total               8858 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        8180 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         123 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0021  ? 8518  ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 0.5139  ? 11600 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0436  ? 1222  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0049  ? 1498  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.2836 ? 3168  ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 2.70 2.77  . . 140 2612 95.89 . . . . 0.2459 . . . . . . . . . . . 0.3100 
'X-RAY DIFFRACTION' 2.77 2.85  . . 134 2701 97.42 . . . . 0.2282 . . . . . . . . . . . 0.2894 
'X-RAY DIFFRACTION' 2.85 2.95  . . 148 2689 97.86 . . . . 0.2242 . . . . . . . . . . . 0.2651 
'X-RAY DIFFRACTION' 2.95 3.05  . . 146 2709 98.18 . . . . 0.2096 . . . . . . . . . . . 0.2702 
'X-RAY DIFFRACTION' 3.05 3.17  . . 139 2717 99.03 . . . . 0.1998 . . . . . . . . . . . 0.2515 
'X-RAY DIFFRACTION' 3.17 3.32  . . 141 2707 98.99 . . . . 0.1975 . . . . . . . . . . . 0.1941 
'X-RAY DIFFRACTION' 3.32 3.49  . . 150 2738 98.77 . . . . 0.1934 . . . . . . . . . . . 0.2327 
'X-RAY DIFFRACTION' 3.49 3.71  . . 140 2668 97.94 . . . . 0.1792 . . . . . . . . . . . 0.2154 
'X-RAY DIFFRACTION' 3.71 3.99  . . 142 2722 98.08 . . . . 0.1699 . . . . . . . . . . . 0.2357 
'X-RAY DIFFRACTION' 3.99 4.39  . . 144 2700 98.17 . . . . 0.1576 . . . . . . . . . . . 0.1865 
'X-RAY DIFFRACTION' 4.39 5.02  . . 145 2711 97.67 . . . . 0.1542 . . . . . . . . . . . 0.2003 
'X-RAY DIFFRACTION' 5.03 6.31  . . 142 2679 97.14 . . . . 0.1805 . . . . . . . . . . . 0.2328 
'X-RAY DIFFRACTION' 6.31 23.70 . . 135 2631 94.56 . . . . 0.2173 . . . . . . . . . . . 0.2570 
# 
_struct.entry_id                     9BD5 
_struct.title                        'Laccase from Bacillus licheniformis' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BD5 
_struct_keywords.text            OXIDOREDUCTASE 
_struct_keywords.pdbx_keywords   OXIDOREDUCTASE 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A  N N 1 ? 
B  N N 1 ? 
C  N N 2 ? 
D  N N 2 ? 
E  N N 2 ? 
F  N N 2 ? 
G  N N 2 ? 
H  N N 2 ? 
I  N N 3 ? 
J  N N 2 ? 
K  N N 2 ? 
L  N N 2 ? 
M  N N 2 ? 
N  N N 2 ? 
O  N N 3 ? 
P  N N 3 ? 
Q  N N 3 ? 
R  N N 2 ? 
S  N N 2 ? 
T  N N 2 ? 
U  N N 2 ? 
V  N N 2 ? 
W  N N 2 ? 
X  N N 3 ? 
Y  N N 2 ? 
Z  N N 2 ? 
AA N N 2 ? 
BA N N 2 ? 
CA N N 2 ? 
DA N N 2 ? 
EA N N 3 ? 
FA N N 3 ? 
GA N N 3 ? 
HA N N 4 ? 
IA N N 4 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    A0A6N2GR66_9BACI 
_struct_ref.pdbx_db_accession          A0A6N2GR66 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;MKLEKFVDKLPIPKVLKPHSKSKEMTYYEVTMKEFQQQLHRDLPPTRLFGYNGVYPGPTFEVQKHEKVAVKWLNKLPDHH
FLPVDHTIHDDGHHEHEVKTVVHLHGGRTPPDSDGYPEAWYTKDFQVKGPFFEREVYEYPNEQDATALWYHDHAMAITRL
NVYAGLVGLYFIRDREERSLNLPKGEYEIPLLIQDKSFHEDGSLFYPRQPDNPSPDLPDPSIVPAFCGDTILVNGKVWPY
DELEPRKYRFRILNASNTRIFELYFDHDITFHQIGTDGGLLQHPVKVNELVIAPAERCDIIVDFSRAEGKTVTLKNRIGC
SGQDADPDTDANIMQFRISKPLKQKDTSSLPRILRKRPFYRRHKINTLRNLSLGASLDQYGRPVLLLNNTKWHEPVTETP
ALGSTEIWSIINAGRAIHPIHLHLVQFLILDHRPFDIERYQENGELVFTGPAAPPAQNEKGLKDTVKVPPGSVTRIIATF
APYSGRYVWHCHILEHEDYDMMRPLEVTDIRHQ
;
_struct_ref.pdbx_align_begin           1 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BD5 A 1 ? 513 ? A0A6N2GR66 1 ? 513 ? 1 512 
2 1 9BD5 B 1 ? 513 ? A0A6N2GR66 1 ? 513 ? 1 512 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9BD5 GLU A 514 ? UNP A0A6N2GR66 ? ? 'expression tag' 513 1  
1 9BD5 PHE A 515 ? UNP A0A6N2GR66 ? ? 'expression tag' 514 2  
1 9BD5 GLU A 516 ? UNP A0A6N2GR66 ? ? 'expression tag' 515 3  
1 9BD5 ALA A 517 ? UNP A0A6N2GR66 ? ? 'expression tag' 516 4  
1 9BD5 TRP A 518 ? UNP A0A6N2GR66 ? ? 'expression tag' 517 5  
1 9BD5 ALA A 519 ? UNP A0A6N2GR66 ? ? 'expression tag' 518 6  
1 9BD5 ARG A 520 ? UNP A0A6N2GR66 ? ? 'expression tag' 519 7  
1 9BD5 THR A 521 ? UNP A0A6N2GR66 ? ? 'expression tag' 520 8  
1 9BD5 LYS A 522 ? UNP A0A6N2GR66 ? ? 'expression tag' 521 9  
1 9BD5 THR A 523 ? UNP A0A6N2GR66 ? ? 'expression tag' 522 10 
1 9BD5 HIS A 524 ? UNP A0A6N2GR66 ? ? 'expression tag' 523 11 
1 9BD5 LEU A 525 ? UNP A0A6N2GR66 ? ? 'expression tag' 524 12 
1 9BD5 ARG A 526 ? UNP A0A6N2GR66 ? ? 'expression tag' 525 13 
1 9BD5 ARG A 527 ? UNP A0A6N2GR66 ? ? 'expression tag' 526 14 
1 9BD5 GLY A 528 ? UNP A0A6N2GR66 ? ? 'expression tag' 527 15 
1 9BD5 SER A 529 ? UNP A0A6N2GR66 ? ? 'expression tag' 528 16 
1 9BD5 GLU A 530 ? UNP A0A6N2GR66 ? ? 'expression tag' 529 17 
2 9BD5 GLU B 514 ? UNP A0A6N2GR66 ? ? 'expression tag' 513 18 
2 9BD5 PHE B 515 ? UNP A0A6N2GR66 ? ? 'expression tag' 514 19 
2 9BD5 GLU B 516 ? UNP A0A6N2GR66 ? ? 'expression tag' 515 20 
2 9BD5 ALA B 517 ? UNP A0A6N2GR66 ? ? 'expression tag' 516 21 
2 9BD5 TRP B 518 ? UNP A0A6N2GR66 ? ? 'expression tag' 517 22 
2 9BD5 ALA B 519 ? UNP A0A6N2GR66 ? ? 'expression tag' 518 23 
2 9BD5 ARG B 520 ? UNP A0A6N2GR66 ? ? 'expression tag' 519 24 
2 9BD5 THR B 521 ? UNP A0A6N2GR66 ? ? 'expression tag' 520 25 
2 9BD5 LYS B 522 ? UNP A0A6N2GR66 ? ? 'expression tag' 521 26 
2 9BD5 THR B 523 ? UNP A0A6N2GR66 ? ? 'expression tag' 522 27 
2 9BD5 HIS B 524 ? UNP A0A6N2GR66 ? ? 'expression tag' 523 28 
2 9BD5 LEU B 525 ? UNP A0A6N2GR66 ? ? 'expression tag' 524 29 
2 9BD5 ARG B 526 ? UNP A0A6N2GR66 ? ? 'expression tag' 525 30 
2 9BD5 ARG B 527 ? UNP A0A6N2GR66 ? ? 'expression tag' 526 31 
2 9BD5 GLY B 528 ? UNP A0A6N2GR66 ? ? 'expression tag' 527 32 
2 9BD5 SER B 529 ? UNP A0A6N2GR66 ? ? 'expression tag' 528 33 
2 9BD5 GLU B 530 ? UNP A0A6N2GR66 ? ? 'expression tag' 529 34 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 6470  ? 
1 MORE         -382  ? 
1 'SSA (A^2)'  39950 ? 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C,D,E,F,G,H,I,J,K,L,M,N,O,P,Q,R,S,T,U,V,W,X,Y,Z,AA,BA,CA,DA,EA,FA,GA,HA,IA 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   none 
_pdbx_struct_assembly_auth_evidence.details                ? 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   x,y,z 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 PRO A 110 ? ASP A 114 ? PRO A 110 ASP A 114 5 ? 5 
HELX_P HELX_P2  AA2 THR A 122 ? GLN A 126 ? THR A 122 GLN A 126 5 ? 5 
HELX_P HELX_P3  AA3 ILE A 157 ? ALA A 164 ? ILE A 157 ALA A 164 1 ? 8 
HELX_P HELX_P4  AA4 ASP A 174 ? LEU A 180 ? ASP A 174 LEU A 180 1 ? 7 
HELX_P HELX_P5  AA5 LYS A 184 ? GLU A 186 ? LYS A 184 GLU A 186 5 ? 3 
HELX_P HELX_P6  AA6 SER A 305 ? GLU A 308 ? SER A 305 GLU A 308 5 ? 4 
HELX_P HELX_P7  AA7 ASP A 436 ? GLY A 444 ? ASP A 435 GLY A 443 1 ? 9 
HELX_P HELX_P8  AA8 ALA A 456 ? LYS A 460 ? ALA A 455 LYS A 459 5 ? 5 
HELX_P HELX_P9  AA9 ILE A 493 ? ASP A 498 ? ILE A 492 ASP A 497 1 ? 6 
HELX_P HELX_P10 AB1 PRO B 110 ? ASP B 114 ? PRO B 110 ASP B 114 5 ? 5 
HELX_P HELX_P11 AB2 THR B 122 ? GLN B 126 ? THR B 122 GLN B 126 5 ? 5 
HELX_P HELX_P12 AB3 ILE B 157 ? ALA B 164 ? ILE B 157 ALA B 164 1 ? 8 
HELX_P HELX_P13 AB4 ASP B 174 ? LEU B 180 ? ASP B 174 LEU B 180 1 ? 7 
HELX_P HELX_P14 AB5 LYS B 184 ? GLU B 186 ? LYS B 184 GLU B 186 5 ? 3 
HELX_P HELX_P15 AB6 ASP B 436 ? GLN B 441 ? ASP B 435 GLN B 440 1 ? 6 
HELX_P HELX_P16 AB7 ALA B 456 ? LYS B 460 ? ALA B 455 LYS B 459 5 ? 5 
HELX_P HELX_P17 AB8 ILE B 493 ? ASP B 498 ? ILE B 492 ASP B 497 1 ? 6 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1  disulf ? ? A CYS 227 SG  ? ? ? 1_555 A  CYS 320 SG ? ? A CYS 227 A CYS 320 1_555 ? ? ? ? ? ? ? 2.022 ? ? 
disulf2  disulf ? ? B CYS 227 SG  ? ? ? 1_555 B  CYS 320 SG ? ? B CYS 227 B CYS 320 1_555 ? ? ? ? ? ? ? 2.020 ? ? 
metalc1  metalc ? ? A HIS 103 NE2 ? ? ? 1_555 P  CU  .   CU ? ? A HIS 103 A CU  614 1_555 ? ? ? ? ? ? ? 2.115 ? ? 
metalc2  metalc ? ? A HIS 105 ND1 ? ? ? 1_555 Q  CU  .   CU ? ? A HIS 105 A CU  615 1_555 ? ? ? ? ? ? ? 2.053 ? ? 
metalc3  metalc ? ? A HIS 151 NE2 ? ? ? 1_555 Q  CU  .   CU ? ? A HIS 151 A CU  615 1_555 ? ? ? ? ? ? ? 2.143 ? ? 
metalc4  metalc ? ? A HIS 153 NE2 ? ? ? 1_555 O  CU  .   CU ? ? A HIS 153 A CU  613 1_555 ? ? ? ? ? ? ? 2.261 ? ? 
metalc5  metalc ? ? A HIS 418 ND1 ? ? ? 1_555 I  CU  .   CU ? ? A HIS 417 A CU  607 1_555 ? ? ? ? ? ? ? 2.212 ? ? 
metalc6  metalc ? ? A HIS 421 NE2 ? ? ? 1_555 P  CU  .   CU ? ? A HIS 420 A CU  614 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
metalc7  metalc ? ? A HIS 423 NE2 ? ? ? 1_555 O  CU  .   CU ? ? A HIS 422 A CU  613 1_555 ? ? ? ? ? ? ? 2.130 ? ? 
metalc8  metalc ? ? A HIS 490 NE2 ? ? ? 1_555 O  CU  .   CU ? ? A HIS 489 A CU  613 1_555 ? ? ? ? ? ? ? 2.062 ? ? 
metalc9  metalc ? ? A CYS 491 SG  ? ? ? 1_555 I  CU  .   CU ? ? A CYS 490 A CU  607 1_555 ? ? ? ? ? ? ? 2.327 ? ? 
metalc10 metalc ? ? A HIS 492 NE2 ? ? ? 1_555 Q  CU  .   CU ? ? A HIS 491 A CU  615 1_555 ? ? ? ? ? ? ? 2.147 ? ? 
metalc11 metalc ? ? A HIS 496 ND1 ? ? ? 1_555 I  CU  .   CU ? ? A HIS 495 A CU  607 1_555 ? ? ? ? ? ? ? 2.168 ? ? 
metalc12 metalc ? ? B HIS 103 NE2 ? ? ? 1_555 FA CU  .   CU ? ? B HIS 103 B CU  614 1_555 ? ? ? ? ? ? ? 2.114 ? ? 
metalc13 metalc ? ? B HIS 105 ND1 ? ? ? 1_555 GA CU  .   CU ? ? B HIS 105 B CU  615 1_555 ? ? ? ? ? ? ? 2.024 ? ? 
metalc14 metalc ? ? B HIS 151 NE2 ? ? ? 1_555 GA CU  .   CU ? ? B HIS 151 B CU  615 1_555 ? ? ? ? ? ? ? 2.113 ? ? 
metalc15 metalc ? ? B HIS 153 NE2 ? ? ? 1_555 EA CU  .   CU ? ? B HIS 153 B CU  613 1_555 ? ? ? ? ? ? ? 2.212 ? ? 
metalc16 metalc ? ? B HIS 418 ND1 ? ? ? 1_555 X  CU  .   CU ? ? B HIS 417 B CU  606 1_555 ? ? ? ? ? ? ? 2.219 ? ? 
metalc17 metalc ? ? B HIS 421 NE2 ? ? ? 1_555 FA CU  .   CU ? ? B HIS 420 B CU  614 1_555 ? ? ? ? ? ? ? 2.073 ? ? 
metalc18 metalc ? ? B HIS 423 NE2 ? ? ? 1_555 EA CU  .   CU ? ? B HIS 422 B CU  613 1_555 ? ? ? ? ? ? ? 2.085 ? ? 
metalc19 metalc ? ? B HIS 490 NE2 ? ? ? 1_555 EA CU  .   CU ? ? B HIS 489 B CU  613 1_555 ? ? ? ? ? ? ? 2.048 ? ? 
metalc20 metalc ? ? B CYS 491 SG  ? ? ? 1_555 X  CU  .   CU ? ? B CYS 490 B CU  606 1_555 ? ? ? ? ? ? ? 2.366 ? ? 
metalc21 metalc ? ? B HIS 492 NE2 ? ? ? 1_555 GA CU  .   CU ? ? B HIS 491 B CU  615 1_555 ? ? ? ? ? ? ? 2.167 ? ? 
metalc22 metalc ? ? B HIS 496 ND1 ? ? ? 1_555 X  CU  .   CU ? ? B HIS 495 B CU  606 1_555 ? ? ? ? ? ? ? 2.178 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
metalc ? ? 
# 
loop_
_pdbx_struct_conn_angle.id 
_pdbx_struct_conn_angle.ptnr1_label_atom_id 
_pdbx_struct_conn_angle.ptnr1_label_alt_id 
_pdbx_struct_conn_angle.ptnr1_label_asym_id 
_pdbx_struct_conn_angle.ptnr1_label_comp_id 
_pdbx_struct_conn_angle.ptnr1_label_seq_id 
_pdbx_struct_conn_angle.ptnr1_auth_atom_id 
_pdbx_struct_conn_angle.ptnr1_auth_asym_id 
_pdbx_struct_conn_angle.ptnr1_auth_comp_id 
_pdbx_struct_conn_angle.ptnr1_auth_seq_id 
_pdbx_struct_conn_angle.ptnr1_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr1_symmetry 
_pdbx_struct_conn_angle.ptnr2_label_atom_id 
_pdbx_struct_conn_angle.ptnr2_label_alt_id 
_pdbx_struct_conn_angle.ptnr2_label_asym_id 
_pdbx_struct_conn_angle.ptnr2_label_comp_id 
_pdbx_struct_conn_angle.ptnr2_label_seq_id 
_pdbx_struct_conn_angle.ptnr2_auth_atom_id 
_pdbx_struct_conn_angle.ptnr2_auth_asym_id 
_pdbx_struct_conn_angle.ptnr2_auth_comp_id 
_pdbx_struct_conn_angle.ptnr2_auth_seq_id 
_pdbx_struct_conn_angle.ptnr2_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr2_symmetry 
_pdbx_struct_conn_angle.ptnr3_label_atom_id 
_pdbx_struct_conn_angle.ptnr3_label_alt_id 
_pdbx_struct_conn_angle.ptnr3_label_asym_id 
_pdbx_struct_conn_angle.ptnr3_label_comp_id 
_pdbx_struct_conn_angle.ptnr3_label_seq_id 
_pdbx_struct_conn_angle.ptnr3_auth_atom_id 
_pdbx_struct_conn_angle.ptnr3_auth_asym_id 
_pdbx_struct_conn_angle.ptnr3_auth_comp_id 
_pdbx_struct_conn_angle.ptnr3_auth_seq_id 
_pdbx_struct_conn_angle.ptnr3_PDB_ins_code 
_pdbx_struct_conn_angle.ptnr3_symmetry 
_pdbx_struct_conn_angle.value 
_pdbx_struct_conn_angle.value_esd 
1  NE2 ? A HIS 103 ? A HIS 103 ? 1_555 CU ? P  CU . ? A CU 614 ? 1_555 NE2 ? A HIS 421 ? A HIS 420 ? 1_555 171.0 ? 
2  ND1 ? A HIS 105 ? A HIS 105 ? 1_555 CU ? Q  CU . ? A CU 615 ? 1_555 NE2 ? A HIS 151 ? A HIS 151 ? 1_555 141.2 ? 
3  ND1 ? A HIS 105 ? A HIS 105 ? 1_555 CU ? Q  CU . ? A CU 615 ? 1_555 NE2 ? A HIS 492 ? A HIS 491 ? 1_555 102.3 ? 
4  NE2 ? A HIS 151 ? A HIS 151 ? 1_555 CU ? Q  CU . ? A CU 615 ? 1_555 NE2 ? A HIS 492 ? A HIS 491 ? 1_555 115.0 ? 
5  NE2 ? A HIS 153 ? A HIS 153 ? 1_555 CU ? O  CU . ? A CU 613 ? 1_555 NE2 ? A HIS 423 ? A HIS 422 ? 1_555 106.9 ? 
6  NE2 ? A HIS 153 ? A HIS 153 ? 1_555 CU ? O  CU . ? A CU 613 ? 1_555 NE2 ? A HIS 490 ? A HIS 489 ? 1_555 110.3 ? 
7  NE2 ? A HIS 423 ? A HIS 422 ? 1_555 CU ? O  CU . ? A CU 613 ? 1_555 NE2 ? A HIS 490 ? A HIS 489 ? 1_555 112.1 ? 
8  ND1 ? A HIS 418 ? A HIS 417 ? 1_555 CU ? I  CU . ? A CU 607 ? 1_555 SG  ? A CYS 491 ? A CYS 490 ? 1_555 123.6 ? 
9  ND1 ? A HIS 418 ? A HIS 417 ? 1_555 CU ? I  CU . ? A CU 607 ? 1_555 ND1 ? A HIS 496 ? A HIS 495 ? 1_555 111.7 ? 
10 SG  ? A CYS 491 ? A CYS 490 ? 1_555 CU ? I  CU . ? A CU 607 ? 1_555 ND1 ? A HIS 496 ? A HIS 495 ? 1_555 124.1 ? 
11 NE2 ? B HIS 103 ? B HIS 103 ? 1_555 CU ? FA CU . ? B CU 614 ? 1_555 NE2 ? B HIS 421 ? B HIS 420 ? 1_555 164.9 ? 
12 ND1 ? B HIS 105 ? B HIS 105 ? 1_555 CU ? GA CU . ? B CU 615 ? 1_555 NE2 ? B HIS 151 ? B HIS 151 ? 1_555 133.5 ? 
13 ND1 ? B HIS 105 ? B HIS 105 ? 1_555 CU ? GA CU . ? B CU 615 ? 1_555 NE2 ? B HIS 492 ? B HIS 491 ? 1_555 102.3 ? 
14 NE2 ? B HIS 151 ? B HIS 151 ? 1_555 CU ? GA CU . ? B CU 615 ? 1_555 NE2 ? B HIS 492 ? B HIS 491 ? 1_555 115.8 ? 
15 NE2 ? B HIS 153 ? B HIS 153 ? 1_555 CU ? EA CU . ? B CU 613 ? 1_555 NE2 ? B HIS 423 ? B HIS 422 ? 1_555 110.7 ? 
16 NE2 ? B HIS 153 ? B HIS 153 ? 1_555 CU ? EA CU . ? B CU 613 ? 1_555 NE2 ? B HIS 490 ? B HIS 489 ? 1_555 107.9 ? 
17 NE2 ? B HIS 423 ? B HIS 422 ? 1_555 CU ? EA CU . ? B CU 613 ? 1_555 NE2 ? B HIS 490 ? B HIS 489 ? 1_555 109.1 ? 
18 ND1 ? B HIS 418 ? B HIS 417 ? 1_555 CU ? X  CU . ? B CU 606 ? 1_555 SG  ? B CYS 491 ? B CYS 490 ? 1_555 123.5 ? 
19 ND1 ? B HIS 418 ? B HIS 417 ? 1_555 CU ? X  CU . ? B CU 606 ? 1_555 ND1 ? B HIS 496 ? B HIS 495 ? 1_555 112.7 ? 
20 SG  ? B CYS 491 ? B CYS 490 ? 1_555 CU ? X  CU . ? B CU 606 ? 1_555 ND1 ? B HIS 496 ? B HIS 495 ? 1_555 118.9 ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 227 ? CYS A 320 ? CYS A 227 ? 1_555 CYS A 320 ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 227 ? CYS B 320 ? CYS B 227 ? 1_555 CYS B 320 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_mon_prot_cis.pdbx_id 
_struct_mon_prot_cis.label_comp_id 
_struct_mon_prot_cis.label_seq_id 
_struct_mon_prot_cis.label_asym_id 
_struct_mon_prot_cis.label_alt_id 
_struct_mon_prot_cis.pdbx_PDB_ins_code 
_struct_mon_prot_cis.auth_comp_id 
_struct_mon_prot_cis.auth_seq_id 
_struct_mon_prot_cis.auth_asym_id 
_struct_mon_prot_cis.pdbx_label_comp_id_2 
_struct_mon_prot_cis.pdbx_label_seq_id_2 
_struct_mon_prot_cis.pdbx_label_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2 
_struct_mon_prot_cis.pdbx_auth_comp_id_2 
_struct_mon_prot_cis.pdbx_auth_seq_id_2 
_struct_mon_prot_cis.pdbx_auth_asym_id_2 
_struct_mon_prot_cis.pdbx_PDB_model_num 
_struct_mon_prot_cis.pdbx_omega_angle 
1 TYR 55  A . ? TYR 55  A PRO 56  A ? PRO 56  A 1 -2.13 
2 ASP 219 A . ? ASP 219 A PRO 220 A ? PRO 220 A 1 -0.10 
3 ALA 481 A . ? ALA 480 A PRO 482 A ? PRO 481 A 1 -1.78 
4 TYR 499 A . ? TYR 498 A ASP 500 A ? ASP 499 A 1 -2.81 
5 TYR 55  B . ? TYR 55  B PRO 56  B ? PRO 56  B 1 -2.44 
6 ASP 219 B . ? ASP 219 B PRO 220 B ? PRO 220 B 1 -1.15 
7 ALA 481 B . ? ALA 480 B PRO 482 B ? PRO 481 B 1 -0.76 
8 TYR 499 B . ? TYR 498 B ASP 500 B ? ASP 499 B 1 -2.32 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 3 ? 
AA2 ? 4 ? 
AA3 ? 4 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 5 ? 
AA7 ? 4 ? 
AA8 ? 3 ? 
AA9 ? 4 ? 
AB1 ? 4 ? 
AB2 ? 7 ? 
AB3 ? 5 ? 
AB4 ? 5 ? 
AB5 ? 4 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA2 1 2 ? anti-parallel 
AA2 2 3 ? parallel      
AA2 3 4 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? parallel      
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? anti-parallel 
AA6 2 3 ? parallel      
AA6 3 4 ? anti-parallel 
AA6 4 5 ? anti-parallel 
AA7 1 2 ? anti-parallel 
AA7 2 3 ? anti-parallel 
AA7 3 4 ? anti-parallel 
AA8 1 2 ? anti-parallel 
AA8 2 3 ? anti-parallel 
AA9 1 2 ? anti-parallel 
AA9 2 3 ? parallel      
AA9 3 4 ? anti-parallel 
AB1 1 2 ? parallel      
AB1 2 3 ? anti-parallel 
AB1 3 4 ? anti-parallel 
AB2 1 2 ? anti-parallel 
AB2 2 3 ? anti-parallel 
AB2 3 4 ? parallel      
AB2 4 5 ? anti-parallel 
AB2 5 6 ? anti-parallel 
AB2 6 7 ? anti-parallel 
AB3 1 2 ? parallel      
AB3 2 3 ? anti-parallel 
AB3 3 4 ? anti-parallel 
AB3 4 5 ? anti-parallel 
AB4 1 2 ? anti-parallel 
AB4 2 3 ? parallel      
AB4 3 4 ? anti-parallel 
AB4 4 5 ? anti-parallel 
AB5 1 2 ? anti-parallel 
AB5 2 3 ? anti-parallel 
AB5 3 4 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 SER A 20  ? LYS A 21  ? SER A 20  LYS A 21  
AA1 2 THR A 26  ? GLN A 37  ? THR A 26  GLN A 37  
AA1 3 THR A 46  ? TYR A 51  ? THR A 46  TYR A 51  
AA2 1 SER A 20  ? LYS A 21  ? SER A 20  LYS A 21  
AA2 2 THR A 26  ? GLN A 37  ? THR A 26  GLN A 37  
AA2 3 VAL A 68  ? ASN A 74  ? VAL A 68  ASN A 74  
AA2 4 VAL A 136 ? TYR A 139 ? VAL A 136 TYR A 139 
AA3 1 PHE A 60  ? GLN A 63  ? PHE A 60  GLN A 63  
AA3 2 VAL A 167 ? ARG A 173 ? VAL A 167 ARG A 173 
AA3 3 ALA A 147 ? ASP A 152 ? ALA A 147 ASP A 152 
AA3 4 VAL A 102 ? HIS A 105 ? VAL A 102 HIS A 105 
AA4 1 LYS A 236 ? VAL A 237 ? LYS A 236 VAL A 237 
AA4 2 THR A 230 ? VAL A 233 ? THR A 230 VAL A 233 
AA4 3 GLU A 188 ? LYS A 196 ? GLU A 188 LYS A 196 
AA4 4 LYS A 247 ? ASN A 254 ? LYS A 247 ASN A 254 
AA4 5 ARG A 297 ? ASP A 303 ? ARG A 297 ASP A 303 
AA4 6 PHE A 271 ? GLY A 275 ? PHE A 271 GLY A 275 
AA4 7 LEU A 280 ? VAL A 287 ? LEU A 280 VAL A 287 
AA5 1 TYR A 240 ? GLU A 242 ? TYR A 240 GLU A 242 
AA5 2 ASN A 332 ? ARG A 337 ? ASN A 331 ARG A 336 
AA5 3 THR A 311 ? ASN A 316 ? THR A 311 ASN A 316 
AA5 4 PHE A 261 ? PHE A 265 ? PHE A 261 PHE A 265 
AA5 5 LEU A 290 ? ILE A 292 ? LEU A 290 ILE A 292 
AA6 1 PRO A 383 ? LEU A 387 ? PRO A 382 LEU A 386 
AA6 2 THR A 367 ? LEU A 377 ? THR A 366 LEU A 376 
AA6 3 THR A 405 ? ASN A 412 ? THR A 404 ASN A 411 
AA6 4 SER A 472 ? THR A 479 ? SER A 471 THR A 478 
AA6 5 LEU A 428 ? PRO A 434 ? LEU A 427 PRO A 433 
AA7 1 THR A 465 ? VAL A 468 ? THR A 464 VAL A 467 
AA7 2 HIS A 418 ? LEU A 422 ? HIS A 417 LEU A 421 
AA7 3 GLY A 485 ? CYS A 491 ? GLY A 484 CYS A 490 
AA7 4 MET A 502 ? VAL A 507 ? MET A 501 VAL A 506 
AA8 1 SER B 20  ? LYS B 21  ? SER B 20  LYS B 21  
AA8 2 THR B 26  ? GLN B 37  ? THR B 26  GLN B 37  
AA8 3 THR B 46  ? TYR B 51  ? THR B 46  TYR B 51  
AA9 1 SER B 20  ? LYS B 21  ? SER B 20  LYS B 21  
AA9 2 THR B 26  ? GLN B 37  ? THR B 26  GLN B 37  
AA9 3 VAL B 68  ? LYS B 75  ? VAL B 68  LYS B 75  
AA9 4 TYR B 137 ? TYR B 139 ? TYR B 137 TYR B 139 
AB1 1 PHE B 60  ? GLN B 63  ? PHE B 60  GLN B 63  
AB1 2 VAL B 167 ? ARG B 173 ? VAL B 167 ARG B 173 
AB1 3 THR B 146 ? ASP B 152 ? THR B 146 ASP B 152 
AB1 4 VAL B 102 ? HIS B 105 ? VAL B 102 HIS B 105 
AB2 1 LYS B 236 ? VAL B 237 ? LYS B 236 VAL B 237 
AB2 2 THR B 230 ? VAL B 233 ? THR B 230 VAL B 233 
AB2 3 GLU B 188 ? LYS B 196 ? GLU B 188 LYS B 196 
AB2 4 LYS B 247 ? ASN B 254 ? LYS B 247 ASN B 254 
AB2 5 ARG B 297 ? ASP B 303 ? ARG B 297 ASP B 303 
AB2 6 PHE B 271 ? GLY B 275 ? PHE B 271 GLY B 275 
AB2 7 LEU B 280 ? VAL B 287 ? LEU B 280 VAL B 287 
AB3 1 TYR B 240 ? GLU B 242 ? TYR B 240 GLU B 242 
AB3 2 ASN B 332 ? ARG B 337 ? ASN B 331 ARG B 336 
AB3 3 THR B 311 ? ASN B 316 ? THR B 311 ASN B 316 
AB3 4 PHE B 261 ? PHE B 265 ? PHE B 261 PHE B 265 
AB3 5 LEU B 290 ? ILE B 292 ? LEU B 290 ILE B 292 
AB4 1 PRO B 383 ? LEU B 387 ? PRO B 382 LEU B 386 
AB4 2 THR B 367 ? LEU B 377 ? THR B 366 LEU B 376 
AB4 3 THR B 405 ? ASN B 412 ? THR B 404 ASN B 411 
AB4 4 SER B 472 ? THR B 479 ? SER B 471 THR B 478 
AB4 5 LEU B 428 ? PRO B 434 ? LEU B 427 PRO B 433 
AB5 1 THR B 465 ? VAL B 468 ? THR B 464 VAL B 467 
AB5 2 HIS B 418 ? LEU B 422 ? HIS B 417 LEU B 421 
AB5 3 GLY B 485 ? CYS B 491 ? GLY B 484 CYS B 490 
AB5 4 MET B 502 ? VAL B 507 ? MET B 501 VAL B 506 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 20  ? N SER A 20  O TYR A 27  ? O TYR A 27  
AA1 2 3 N PHE A 35  ? N PHE A 35  O LEU A 48  ? O LEU A 48  
AA2 1 2 N SER A 20  ? N SER A 20  O TYR A 27  ? O TYR A 27  
AA2 2 3 N TYR A 28  ? N TYR A 28  O ALA A 69  ? O ALA A 69  
AA2 3 4 N VAL A 68  ? N VAL A 68  O TYR A 139 ? O TYR A 139 
AA3 1 2 N PHE A 60  ? N PHE A 60  O PHE A 171 ? O PHE A 171 
AA3 2 3 O TYR A 170 ? O TYR A 170 N LEU A 148 ? N LEU A 148 
AA3 3 4 O HIS A 151 ? O HIS A 151 N HIS A 103 ? N HIS A 103 
AA4 1 2 O LYS A 236 ? O LYS A 236 N VAL A 233 ? N VAL A 233 
AA4 2 3 O LEU A 232 ? O LEU A 232 N GLN A 194 ? N GLN A 194 
AA4 3 4 N LEU A 191 ? N LEU A 191 O LEU A 253 ? O LEU A 253 
AA4 4 5 N TYR A 248 ? N TYR A 248 O VAL A 302 ? O VAL A 302 
AA4 5 6 O ASP A 299 ? O ASP A 299 N ILE A 274 ? N ILE A 274 
AA4 6 7 N ILE A 274 ? N ILE A 274 O LEU A 281 ? O LEU A 281 
AA5 1 2 N ASP A 241 ? N ASP A 241 O ARG A 337 ? O ARG A 336 
AA5 2 3 O PHE A 336 ? O PHE A 335 N VAL A 312 ? N VAL A 312 
AA5 3 4 O LYS A 315 ? O LYS A 315 N TYR A 264 ? N TYR A 264 
AA5 4 5 N LEU A 263 ? N LEU A 263 O LEU A 290 ? O LEU A 290 
AA6 1 2 O VAL A 384 ? O VAL A 383 N SER A 376 ? N SER A 375 
AA6 2 3 N LEU A 371 ? N LEU A 370 O ILE A 411 ? O ILE A 410 
AA6 3 4 N ILE A 410 ? N ILE A 409 O THR A 474 ? O THR A 473 
AA6 4 5 O VAL A 473 ? O VAL A 472 N ARG A 433 ? N ARG A 432 
AA7 1 2 O VAL A 466 ? O VAL A 465 N ILE A 420 ? N ILE A 419 
AA7 2 3 N HIS A 421 ? N HIS A 420 O HIS A 490 ? O HIS A 489 
AA7 3 4 N TYR A 487 ? N TYR A 486 O LEU A 505 ? O LEU A 504 
AA8 1 2 N SER B 20  ? N SER B 20  O TYR B 27  ? O TYR B 27  
AA8 2 3 N PHE B 35  ? N PHE B 35  O LEU B 48  ? O LEU B 48  
AA9 1 2 N SER B 20  ? N SER B 20  O TYR B 27  ? O TYR B 27  
AA9 2 3 N VAL B 30  ? N VAL B 30  O LEU B 73  ? O LEU B 73  
AA9 3 4 N VAL B 68  ? N VAL B 68  O TYR B 139 ? O TYR B 139 
AB1 1 2 N PHE B 60  ? N PHE B 60  O PHE B 171 ? O PHE B 171 
AB1 2 3 O TYR B 170 ? O TYR B 170 N LEU B 148 ? N LEU B 148 
AB1 3 4 O HIS B 151 ? O HIS B 151 N HIS B 103 ? N HIS B 103 
AB2 1 2 O LYS B 236 ? O LYS B 236 N VAL B 233 ? N VAL B 233 
AB2 2 3 O LEU B 232 ? O LEU B 232 N GLN B 194 ? N GLN B 194 
AB2 3 4 N ILE B 193 ? N ILE B 193 O LEU B 253 ? O LEU B 253 
AB2 4 5 N PHE B 250 ? N PHE B 250 O ILE B 300 ? O ILE B 300 
AB2 5 6 O ASP B 299 ? O ASP B 299 N ILE B 274 ? N ILE B 274 
AB2 6 7 N PHE B 271 ? N PHE B 271 O VAL B 287 ? O VAL B 287 
AB3 1 2 N ASP B 241 ? N ASP B 241 O ARG B 337 ? O ARG B 336 
AB3 2 3 O PHE B 336 ? O PHE B 335 N VAL B 312 ? N VAL B 312 
AB3 3 4 O LYS B 315 ? O LYS B 315 N TYR B 264 ? N TYR B 264 
AB3 4 5 N LEU B 263 ? N LEU B 263 O LEU B 290 ? O LEU B 290 
AB4 1 2 O VAL B 384 ? O VAL B 383 N SER B 376 ? N SER B 375 
AB4 2 3 N LEU B 371 ? N LEU B 370 O ILE B 411 ? O ILE B 410 
AB4 3 4 N TRP B 408 ? N TRP B 407 O ILE B 476 ? O ILE B 475 
AB4 4 5 O VAL B 473 ? O VAL B 472 N ARG B 433 ? N ARG B 432 
AB5 1 2 O VAL B 466 ? O VAL B 465 N ILE B 420 ? N ILE B 419 
AB5 2 3 N HIS B 421 ? N HIS B 420 O HIS B 490 ? O HIS B 489 
AB5 3 4 N TYR B 487 ? N TYR B 486 O LEU B 505 ? O LEU B 504 
# 
_pdbx_entry_details.entry_id                   9BD5 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 LEU A 3   ? ? 65.35   104.67  
2  1 HIS A 65  ? ? 76.38   -9.50   
3  1 GLU A 133 ? ? -158.97 -13.04  
4  1 GLU A 142 ? ? -92.10  51.25   
5  1 HIS A 153 ? ? -141.06 18.52   
6  1 ALA A 156 ? ? 72.26   -10.15  
7  1 PRO A 210 ? ? -58.92  -177.86 
8  1 TRP A 238 ? ? 33.44   63.92   
9  1 THR A 258 ? ? -147.24 -38.52  
10 1 THR A 276 ? ? -122.76 -155.55 
11 1 ALA A 295 ? ? 78.30   -6.53   
12 1 PRO A 327 ? ? -61.20  41.54   
13 1 THR A 328 ? ? -127.79 -51.12  
14 1 ILE A 332 ? ? -100.56 -64.03  
15 1 LYS A 342 ? ? -60.08  -81.08  
16 1 ARG A 354 ? ? -157.75 -39.14  
17 1 LYS A 355 ? ? 60.37   -61.72  
18 1 ILE A 364 ? ? 60.94   102.34  
19 1 LEU A 423 ? ? 65.98   -60.53  
20 1 TYR A 486 ? ? -124.86 -169.91 
21 1 TYR A 498 ? ? -161.40 84.00   
22 1 ASP A 499 ? ? -143.60 44.02   
23 1 ARG A 510 ? ? -139.43 -43.73  
24 1 HIS A 511 ? ? -142.17 36.55   
25 1 LEU B 3   ? ? 60.26   84.35   
26 1 GLU B 133 ? ? -136.57 -45.11  
27 1 ALA B 156 ? ? 71.37   -14.84  
28 1 PRO B 210 ? ? -57.21  176.23  
29 1 TRP B 238 ? ? 32.88   64.13   
30 1 THR B 258 ? ? -141.61 -37.65  
31 1 THR B 276 ? ? -123.57 -156.13 
32 1 ALA B 295 ? ? 79.29   -9.95   
33 1 PRO B 327 ? ? -57.07  44.28   
34 1 THR B 328 ? ? -133.12 -54.32  
35 1 ILE B 332 ? ? -101.73 -67.76  
36 1 LYS B 342 ? ? -60.38  -83.12  
37 1 LEU B 349 ? ? -118.53 77.75   
38 1 LYS B 355 ? ? 57.23   -72.90  
39 1 ILE B 364 ? ? 60.76   96.89   
40 1 LEU B 423 ? ? 68.06   -52.33  
41 1 TYR B 498 ? ? -162.98 83.49   
42 1 ASP B 499 ? ? -147.13 43.38   
43 1 ARG B 510 ? ? -155.47 -29.72  
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z         
2 x-y,x,z+5/6   
3 y,-x+y,z+1/6  
4 -y,x-y,z+2/3  
5 -x+y,-x,z+1/3 
6 -x,-y,z+1/2   
# 
loop_
_pdbx_distant_solvent_atoms.id 
_pdbx_distant_solvent_atoms.PDB_model_num 
_pdbx_distant_solvent_atoms.auth_atom_id 
_pdbx_distant_solvent_atoms.label_alt_id 
_pdbx_distant_solvent_atoms.auth_asym_id 
_pdbx_distant_solvent_atoms.auth_comp_id 
_pdbx_distant_solvent_atoms.auth_seq_id 
_pdbx_distant_solvent_atoms.PDB_ins_code 
_pdbx_distant_solvent_atoms.neighbor_macromolecule_distance 
_pdbx_distant_solvent_atoms.neighbor_ligand_distance 
1 1 O ? A HOH 988 ? 6.52 . 
2 1 O ? B HOH 965 ? 6.04 . 
3 1 O ? B HOH 966 ? 6.45 . 
4 1 O ? B HOH 967 ? 7.31 . 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 A MET 1   ? A MET 1   
2  1 Y 1 A ASP 90  ? A ASP 90  
3  1 Y 1 A ASP 91  ? A ASP 91  
4  1 Y 1 A GLY 92  ? A GLY 92  
5  1 Y 1 A HIS 93  ? A HIS 93  
6  1 Y 1 A HIS 94  ? A HIS 94  
7  1 Y 1 A GLU 95  ? A GLU 95  
8  1 Y 1 A HIS 96  ? A HIS 96  
9  1 Y 1 A ASP 327 A A ASP 328 
10 1 Y 1 A TYR 359 ? A TYR 360 
11 1 Y 1 A ARG 360 ? A ARG 361 
12 1 Y 1 A ARG 361 ? A ARG 362 
13 1 Y 1 A GLU 513 ? A GLU 514 
14 1 Y 1 A PHE 514 ? A PHE 515 
15 1 Y 1 A GLU 515 ? A GLU 516 
16 1 Y 1 A ALA 516 ? A ALA 517 
17 1 Y 1 A TRP 517 ? A TRP 518 
18 1 Y 1 A ALA 518 ? A ALA 519 
19 1 Y 1 A ARG 519 ? A ARG 520 
20 1 Y 1 A THR 520 ? A THR 521 
21 1 Y 1 A LYS 521 ? A LYS 522 
22 1 Y 1 A THR 522 ? A THR 523 
23 1 Y 1 A HIS 523 ? A HIS 524 
24 1 Y 1 A LEU 524 ? A LEU 525 
25 1 Y 1 A ARG 525 ? A ARG 526 
26 1 Y 1 A ARG 526 ? A ARG 527 
27 1 Y 1 A GLY 527 ? A GLY 528 
28 1 Y 1 A SER 528 ? A SER 529 
29 1 Y 1 A GLU 529 ? A GLU 530 
30 1 Y 1 B MET 1   ? B MET 1   
31 1 Y 1 B ASP 90  ? B ASP 90  
32 1 Y 1 B ASP 91  ? B ASP 91  
33 1 Y 1 B GLY 92  ? B GLY 92  
34 1 Y 1 B HIS 93  ? B HIS 93  
35 1 Y 1 B HIS 94  ? B HIS 94  
36 1 Y 1 B GLU 95  ? B GLU 95  
37 1 Y 1 B HIS 96  ? B HIS 96  
38 1 Y 1 B ASP 327 A B ASP 328 
39 1 Y 1 B TYR 359 ? B TYR 360 
40 1 Y 1 B ARG 360 ? B ARG 361 
41 1 Y 1 B ARG 361 ? B ARG 362 
42 1 Y 1 B GLU 513 ? B GLU 514 
43 1 Y 1 B PHE 514 ? B PHE 515 
44 1 Y 1 B GLU 515 ? B GLU 516 
45 1 Y 1 B ALA 516 ? B ALA 517 
46 1 Y 1 B TRP 517 ? B TRP 518 
47 1 Y 1 B ALA 518 ? B ALA 519 
48 1 Y 1 B ARG 519 ? B ARG 520 
49 1 Y 1 B THR 520 ? B THR 521 
50 1 Y 1 B LYS 521 ? B LYS 522 
51 1 Y 1 B THR 522 ? B THR 523 
52 1 Y 1 B HIS 523 ? B HIS 524 
53 1 Y 1 B LEU 524 ? B LEU 525 
54 1 Y 1 B ARG 525 ? B ARG 526 
55 1 Y 1 B ARG 526 ? B ARG 527 
56 1 Y 1 B GLY 527 ? B GLY 528 
57 1 Y 1 B SER 528 ? B SER 529 
58 1 Y 1 B GLU 529 ? B GLU 530 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N  N N 1   
ALA CA   C  N S 2   
ALA C    C  N N 3   
ALA O    O  N N 4   
ALA CB   C  N N 5   
ALA OXT  O  N N 6   
ALA H    H  N N 7   
ALA H2   H  N N 8   
ALA HA   H  N N 9   
ALA HB1  H  N N 10  
ALA HB2  H  N N 11  
ALA HB3  H  N N 12  
ALA HXT  H  N N 13  
ARG N    N  N N 14  
ARG CA   C  N S 15  
ARG C    C  N N 16  
ARG O    O  N N 17  
ARG CB   C  N N 18  
ARG CG   C  N N 19  
ARG CD   C  N N 20  
ARG NE   N  N N 21  
ARG CZ   C  N N 22  
ARG NH1  N  N N 23  
ARG NH2  N  N N 24  
ARG OXT  O  N N 25  
ARG H    H  N N 26  
ARG H2   H  N N 27  
ARG HA   H  N N 28  
ARG HB2  H  N N 29  
ARG HB3  H  N N 30  
ARG HG2  H  N N 31  
ARG HG3  H  N N 32  
ARG HD2  H  N N 33  
ARG HD3  H  N N 34  
ARG HE   H  N N 35  
ARG HH11 H  N N 36  
ARG HH12 H  N N 37  
ARG HH21 H  N N 38  
ARG HH22 H  N N 39  
ARG HXT  H  N N 40  
ASN N    N  N N 41  
ASN CA   C  N S 42  
ASN C    C  N N 43  
ASN O    O  N N 44  
ASN CB   C  N N 45  
ASN CG   C  N N 46  
ASN OD1  O  N N 47  
ASN ND2  N  N N 48  
ASN OXT  O  N N 49  
ASN H    H  N N 50  
ASN H2   H  N N 51  
ASN HA   H  N N 52  
ASN HB2  H  N N 53  
ASN HB3  H  N N 54  
ASN HD21 H  N N 55  
ASN HD22 H  N N 56  
ASN HXT  H  N N 57  
ASP N    N  N N 58  
ASP CA   C  N S 59  
ASP C    C  N N 60  
ASP O    O  N N 61  
ASP CB   C  N N 62  
ASP CG   C  N N 63  
ASP OD1  O  N N 64  
ASP OD2  O  N N 65  
ASP OXT  O  N N 66  
ASP H    H  N N 67  
ASP H2   H  N N 68  
ASP HA   H  N N 69  
ASP HB2  H  N N 70  
ASP HB3  H  N N 71  
ASP HD2  H  N N 72  
ASP HXT  H  N N 73  
CU  CU   CU N N 74  
CYS N    N  N N 75  
CYS CA   C  N R 76  
CYS C    C  N N 77  
CYS O    O  N N 78  
CYS CB   C  N N 79  
CYS SG   S  N N 80  
CYS OXT  O  N N 81  
CYS H    H  N N 82  
CYS H2   H  N N 83  
CYS HA   H  N N 84  
CYS HB2  H  N N 85  
CYS HB3  H  N N 86  
CYS HG   H  N N 87  
CYS HXT  H  N N 88  
GLN N    N  N N 89  
GLN CA   C  N S 90  
GLN C    C  N N 91  
GLN O    O  N N 92  
GLN CB   C  N N 93  
GLN CG   C  N N 94  
GLN CD   C  N N 95  
GLN OE1  O  N N 96  
GLN NE2  N  N N 97  
GLN OXT  O  N N 98  
GLN H    H  N N 99  
GLN H2   H  N N 100 
GLN HA   H  N N 101 
GLN HB2  H  N N 102 
GLN HB3  H  N N 103 
GLN HG2  H  N N 104 
GLN HG3  H  N N 105 
GLN HE21 H  N N 106 
GLN HE22 H  N N 107 
GLN HXT  H  N N 108 
GLU N    N  N N 109 
GLU CA   C  N S 110 
GLU C    C  N N 111 
GLU O    O  N N 112 
GLU CB   C  N N 113 
GLU CG   C  N N 114 
GLU CD   C  N N 115 
GLU OE1  O  N N 116 
GLU OE2  O  N N 117 
GLU OXT  O  N N 118 
GLU H    H  N N 119 
GLU H2   H  N N 120 
GLU HA   H  N N 121 
GLU HB2  H  N N 122 
GLU HB3  H  N N 123 
GLU HG2  H  N N 124 
GLU HG3  H  N N 125 
GLU HE2  H  N N 126 
GLU HXT  H  N N 127 
GLY N    N  N N 128 
GLY CA   C  N N 129 
GLY C    C  N N 130 
GLY O    O  N N 131 
GLY OXT  O  N N 132 
GLY H    H  N N 133 
GLY H2   H  N N 134 
GLY HA2  H  N N 135 
GLY HA3  H  N N 136 
GLY HXT  H  N N 137 
HIS N    N  N N 138 
HIS CA   C  N S 139 
HIS C    C  N N 140 
HIS O    O  N N 141 
HIS CB   C  N N 142 
HIS CG   C  Y N 143 
HIS ND1  N  Y N 144 
HIS CD2  C  Y N 145 
HIS CE1  C  Y N 146 
HIS NE2  N  Y N 147 
HIS OXT  O  N N 148 
HIS H    H  N N 149 
HIS H2   H  N N 150 
HIS HA   H  N N 151 
HIS HB2  H  N N 152 
HIS HB3  H  N N 153 
HIS HD1  H  N N 154 
HIS HD2  H  N N 155 
HIS HE1  H  N N 156 
HIS HE2  H  N N 157 
HIS HXT  H  N N 158 
HOH O    O  N N 159 
HOH H1   H  N N 160 
HOH H2   H  N N 161 
ILE N    N  N N 162 
ILE CA   C  N S 163 
ILE C    C  N N 164 
ILE O    O  N N 165 
ILE CB   C  N S 166 
ILE CG1  C  N N 167 
ILE CG2  C  N N 168 
ILE CD1  C  N N 169 
ILE OXT  O  N N 170 
ILE H    H  N N 171 
ILE H2   H  N N 172 
ILE HA   H  N N 173 
ILE HB   H  N N 174 
ILE HG12 H  N N 175 
ILE HG13 H  N N 176 
ILE HG21 H  N N 177 
ILE HG22 H  N N 178 
ILE HG23 H  N N 179 
ILE HD11 H  N N 180 
ILE HD12 H  N N 181 
ILE HD13 H  N N 182 
ILE HXT  H  N N 183 
LEU N    N  N N 184 
LEU CA   C  N S 185 
LEU C    C  N N 186 
LEU O    O  N N 187 
LEU CB   C  N N 188 
LEU CG   C  N N 189 
LEU CD1  C  N N 190 
LEU CD2  C  N N 191 
LEU OXT  O  N N 192 
LEU H    H  N N 193 
LEU H2   H  N N 194 
LEU HA   H  N N 195 
LEU HB2  H  N N 196 
LEU HB3  H  N N 197 
LEU HG   H  N N 198 
LEU HD11 H  N N 199 
LEU HD12 H  N N 200 
LEU HD13 H  N N 201 
LEU HD21 H  N N 202 
LEU HD22 H  N N 203 
LEU HD23 H  N N 204 
LEU HXT  H  N N 205 
LYS N    N  N N 206 
LYS CA   C  N S 207 
LYS C    C  N N 208 
LYS O    O  N N 209 
LYS CB   C  N N 210 
LYS CG   C  N N 211 
LYS CD   C  N N 212 
LYS CE   C  N N 213 
LYS NZ   N  N N 214 
LYS OXT  O  N N 215 
LYS H    H  N N 216 
LYS H2   H  N N 217 
LYS HA   H  N N 218 
LYS HB2  H  N N 219 
LYS HB3  H  N N 220 
LYS HG2  H  N N 221 
LYS HG3  H  N N 222 
LYS HD2  H  N N 223 
LYS HD3  H  N N 224 
LYS HE2  H  N N 225 
LYS HE3  H  N N 226 
LYS HZ1  H  N N 227 
LYS HZ2  H  N N 228 
LYS HZ3  H  N N 229 
LYS HXT  H  N N 230 
MET N    N  N N 231 
MET CA   C  N S 232 
MET C    C  N N 233 
MET O    O  N N 234 
MET CB   C  N N 235 
MET CG   C  N N 236 
MET SD   S  N N 237 
MET CE   C  N N 238 
MET OXT  O  N N 239 
MET H    H  N N 240 
MET H2   H  N N 241 
MET HA   H  N N 242 
MET HB2  H  N N 243 
MET HB3  H  N N 244 
MET HG2  H  N N 245 
MET HG3  H  N N 246 
MET HE1  H  N N 247 
MET HE2  H  N N 248 
MET HE3  H  N N 249 
MET HXT  H  N N 250 
PHE N    N  N N 251 
PHE CA   C  N S 252 
PHE C    C  N N 253 
PHE O    O  N N 254 
PHE CB   C  N N 255 
PHE CG   C  Y N 256 
PHE CD1  C  Y N 257 
PHE CD2  C  Y N 258 
PHE CE1  C  Y N 259 
PHE CE2  C  Y N 260 
PHE CZ   C  Y N 261 
PHE OXT  O  N N 262 
PHE H    H  N N 263 
PHE H2   H  N N 264 
PHE HA   H  N N 265 
PHE HB2  H  N N 266 
PHE HB3  H  N N 267 
PHE HD1  H  N N 268 
PHE HD2  H  N N 269 
PHE HE1  H  N N 270 
PHE HE2  H  N N 271 
PHE HZ   H  N N 272 
PHE HXT  H  N N 273 
PRO N    N  N N 274 
PRO CA   C  N S 275 
PRO C    C  N N 276 
PRO O    O  N N 277 
PRO CB   C  N N 278 
PRO CG   C  N N 279 
PRO CD   C  N N 280 
PRO OXT  O  N N 281 
PRO H    H  N N 282 
PRO HA   H  N N 283 
PRO HB2  H  N N 284 
PRO HB3  H  N N 285 
PRO HG2  H  N N 286 
PRO HG3  H  N N 287 
PRO HD2  H  N N 288 
PRO HD3  H  N N 289 
PRO HXT  H  N N 290 
SER N    N  N N 291 
SER CA   C  N S 292 
SER C    C  N N 293 
SER O    O  N N 294 
SER CB   C  N N 295 
SER OG   O  N N 296 
SER OXT  O  N N 297 
SER H    H  N N 298 
SER H2   H  N N 299 
SER HA   H  N N 300 
SER HB2  H  N N 301 
SER HB3  H  N N 302 
SER HG   H  N N 303 
SER HXT  H  N N 304 
SO4 S    S  N N 305 
SO4 O1   O  N N 306 
SO4 O2   O  N N 307 
SO4 O3   O  N N 308 
SO4 O4   O  N N 309 
THR N    N  N N 310 
THR CA   C  N S 311 
THR C    C  N N 312 
THR O    O  N N 313 
THR CB   C  N R 314 
THR OG1  O  N N 315 
THR CG2  C  N N 316 
THR OXT  O  N N 317 
THR H    H  N N 318 
THR H2   H  N N 319 
THR HA   H  N N 320 
THR HB   H  N N 321 
THR HG1  H  N N 322 
THR HG21 H  N N 323 
THR HG22 H  N N 324 
THR HG23 H  N N 325 
THR HXT  H  N N 326 
TRP N    N  N N 327 
TRP CA   C  N S 328 
TRP C    C  N N 329 
TRP O    O  N N 330 
TRP CB   C  N N 331 
TRP CG   C  Y N 332 
TRP CD1  C  Y N 333 
TRP CD2  C  Y N 334 
TRP NE1  N  Y N 335 
TRP CE2  C  Y N 336 
TRP CE3  C  Y N 337 
TRP CZ2  C  Y N 338 
TRP CZ3  C  Y N 339 
TRP CH2  C  Y N 340 
TRP OXT  O  N N 341 
TRP H    H  N N 342 
TRP H2   H  N N 343 
TRP HA   H  N N 344 
TRP HB2  H  N N 345 
TRP HB3  H  N N 346 
TRP HD1  H  N N 347 
TRP HE1  H  N N 348 
TRP HE3  H  N N 349 
TRP HZ2  H  N N 350 
TRP HZ3  H  N N 351 
TRP HH2  H  N N 352 
TRP HXT  H  N N 353 
TYR N    N  N N 354 
TYR CA   C  N S 355 
TYR C    C  N N 356 
TYR O    O  N N 357 
TYR CB   C  N N 358 
TYR CG   C  Y N 359 
TYR CD1  C  Y N 360 
TYR CD2  C  Y N 361 
TYR CE1  C  Y N 362 
TYR CE2  C  Y N 363 
TYR CZ   C  Y N 364 
TYR OH   O  N N 365 
TYR OXT  O  N N 366 
TYR H    H  N N 367 
TYR H2   H  N N 368 
TYR HA   H  N N 369 
TYR HB2  H  N N 370 
TYR HB3  H  N N 371 
TYR HD1  H  N N 372 
TYR HD2  H  N N 373 
TYR HE1  H  N N 374 
TYR HE2  H  N N 375 
TYR HH   H  N N 376 
TYR HXT  H  N N 377 
VAL N    N  N N 378 
VAL CA   C  N S 379 
VAL C    C  N N 380 
VAL O    O  N N 381 
VAL CB   C  N N 382 
VAL CG1  C  N N 383 
VAL CG2  C  N N 384 
VAL OXT  O  N N 385 
VAL H    H  N N 386 
VAL H2   H  N N 387 
VAL HA   H  N N 388 
VAL HB   H  N N 389 
VAL HG11 H  N N 390 
VAL HG12 H  N N 391 
VAL HG13 H  N N 392 
VAL HG21 H  N N 393 
VAL HG22 H  N N 394 
VAL HG23 H  N N 395 
VAL HXT  H  N N 396 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
CYS N   CA   sing N N 70  
CYS N   H    sing N N 71  
CYS N   H2   sing N N 72  
CYS CA  C    sing N N 73  
CYS CA  CB   sing N N 74  
CYS CA  HA   sing N N 75  
CYS C   O    doub N N 76  
CYS C   OXT  sing N N 77  
CYS CB  SG   sing N N 78  
CYS CB  HB2  sing N N 79  
CYS CB  HB3  sing N N 80  
CYS SG  HG   sing N N 81  
CYS OXT HXT  sing N N 82  
GLN N   CA   sing N N 83  
GLN N   H    sing N N 84  
GLN N   H2   sing N N 85  
GLN CA  C    sing N N 86  
GLN CA  CB   sing N N 87  
GLN CA  HA   sing N N 88  
GLN C   O    doub N N 89  
GLN C   OXT  sing N N 90  
GLN CB  CG   sing N N 91  
GLN CB  HB2  sing N N 92  
GLN CB  HB3  sing N N 93  
GLN CG  CD   sing N N 94  
GLN CG  HG2  sing N N 95  
GLN CG  HG3  sing N N 96  
GLN CD  OE1  doub N N 97  
GLN CD  NE2  sing N N 98  
GLN NE2 HE21 sing N N 99  
GLN NE2 HE22 sing N N 100 
GLN OXT HXT  sing N N 101 
GLU N   CA   sing N N 102 
GLU N   H    sing N N 103 
GLU N   H2   sing N N 104 
GLU CA  C    sing N N 105 
GLU CA  CB   sing N N 106 
GLU CA  HA   sing N N 107 
GLU C   O    doub N N 108 
GLU C   OXT  sing N N 109 
GLU CB  CG   sing N N 110 
GLU CB  HB2  sing N N 111 
GLU CB  HB3  sing N N 112 
GLU CG  CD   sing N N 113 
GLU CG  HG2  sing N N 114 
GLU CG  HG3  sing N N 115 
GLU CD  OE1  doub N N 116 
GLU CD  OE2  sing N N 117 
GLU OE2 HE2  sing N N 118 
GLU OXT HXT  sing N N 119 
GLY N   CA   sing N N 120 
GLY N   H    sing N N 121 
GLY N   H2   sing N N 122 
GLY CA  C    sing N N 123 
GLY CA  HA2  sing N N 124 
GLY CA  HA3  sing N N 125 
GLY C   O    doub N N 126 
GLY C   OXT  sing N N 127 
GLY OXT HXT  sing N N 128 
HIS N   CA   sing N N 129 
HIS N   H    sing N N 130 
HIS N   H2   sing N N 131 
HIS CA  C    sing N N 132 
HIS CA  CB   sing N N 133 
HIS CA  HA   sing N N 134 
HIS C   O    doub N N 135 
HIS C   OXT  sing N N 136 
HIS CB  CG   sing N N 137 
HIS CB  HB2  sing N N 138 
HIS CB  HB3  sing N N 139 
HIS CG  ND1  sing Y N 140 
HIS CG  CD2  doub Y N 141 
HIS ND1 CE1  doub Y N 142 
HIS ND1 HD1  sing N N 143 
HIS CD2 NE2  sing Y N 144 
HIS CD2 HD2  sing N N 145 
HIS CE1 NE2  sing Y N 146 
HIS CE1 HE1  sing N N 147 
HIS NE2 HE2  sing N N 148 
HIS OXT HXT  sing N N 149 
HOH O   H1   sing N N 150 
HOH O   H2   sing N N 151 
ILE N   CA   sing N N 152 
ILE N   H    sing N N 153 
ILE N   H2   sing N N 154 
ILE CA  C    sing N N 155 
ILE CA  CB   sing N N 156 
ILE CA  HA   sing N N 157 
ILE C   O    doub N N 158 
ILE C   OXT  sing N N 159 
ILE CB  CG1  sing N N 160 
ILE CB  CG2  sing N N 161 
ILE CB  HB   sing N N 162 
ILE CG1 CD1  sing N N 163 
ILE CG1 HG12 sing N N 164 
ILE CG1 HG13 sing N N 165 
ILE CG2 HG21 sing N N 166 
ILE CG2 HG22 sing N N 167 
ILE CG2 HG23 sing N N 168 
ILE CD1 HD11 sing N N 169 
ILE CD1 HD12 sing N N 170 
ILE CD1 HD13 sing N N 171 
ILE OXT HXT  sing N N 172 
LEU N   CA   sing N N 173 
LEU N   H    sing N N 174 
LEU N   H2   sing N N 175 
LEU CA  C    sing N N 176 
LEU CA  CB   sing N N 177 
LEU CA  HA   sing N N 178 
LEU C   O    doub N N 179 
LEU C   OXT  sing N N 180 
LEU CB  CG   sing N N 181 
LEU CB  HB2  sing N N 182 
LEU CB  HB3  sing N N 183 
LEU CG  CD1  sing N N 184 
LEU CG  CD2  sing N N 185 
LEU CG  HG   sing N N 186 
LEU CD1 HD11 sing N N 187 
LEU CD1 HD12 sing N N 188 
LEU CD1 HD13 sing N N 189 
LEU CD2 HD21 sing N N 190 
LEU CD2 HD22 sing N N 191 
LEU CD2 HD23 sing N N 192 
LEU OXT HXT  sing N N 193 
LYS N   CA   sing N N 194 
LYS N   H    sing N N 195 
LYS N   H2   sing N N 196 
LYS CA  C    sing N N 197 
LYS CA  CB   sing N N 198 
LYS CA  HA   sing N N 199 
LYS C   O    doub N N 200 
LYS C   OXT  sing N N 201 
LYS CB  CG   sing N N 202 
LYS CB  HB2  sing N N 203 
LYS CB  HB3  sing N N 204 
LYS CG  CD   sing N N 205 
LYS CG  HG2  sing N N 206 
LYS CG  HG3  sing N N 207 
LYS CD  CE   sing N N 208 
LYS CD  HD2  sing N N 209 
LYS CD  HD3  sing N N 210 
LYS CE  NZ   sing N N 211 
LYS CE  HE2  sing N N 212 
LYS CE  HE3  sing N N 213 
LYS NZ  HZ1  sing N N 214 
LYS NZ  HZ2  sing N N 215 
LYS NZ  HZ3  sing N N 216 
LYS OXT HXT  sing N N 217 
MET N   CA   sing N N 218 
MET N   H    sing N N 219 
MET N   H2   sing N N 220 
MET CA  C    sing N N 221 
MET CA  CB   sing N N 222 
MET CA  HA   sing N N 223 
MET C   O    doub N N 224 
MET C   OXT  sing N N 225 
MET CB  CG   sing N N 226 
MET CB  HB2  sing N N 227 
MET CB  HB3  sing N N 228 
MET CG  SD   sing N N 229 
MET CG  HG2  sing N N 230 
MET CG  HG3  sing N N 231 
MET SD  CE   sing N N 232 
MET CE  HE1  sing N N 233 
MET CE  HE2  sing N N 234 
MET CE  HE3  sing N N 235 
MET OXT HXT  sing N N 236 
PHE N   CA   sing N N 237 
PHE N   H    sing N N 238 
PHE N   H2   sing N N 239 
PHE CA  C    sing N N 240 
PHE CA  CB   sing N N 241 
PHE CA  HA   sing N N 242 
PHE C   O    doub N N 243 
PHE C   OXT  sing N N 244 
PHE CB  CG   sing N N 245 
PHE CB  HB2  sing N N 246 
PHE CB  HB3  sing N N 247 
PHE CG  CD1  doub Y N 248 
PHE CG  CD2  sing Y N 249 
PHE CD1 CE1  sing Y N 250 
PHE CD1 HD1  sing N N 251 
PHE CD2 CE2  doub Y N 252 
PHE CD2 HD2  sing N N 253 
PHE CE1 CZ   doub Y N 254 
PHE CE1 HE1  sing N N 255 
PHE CE2 CZ   sing Y N 256 
PHE CE2 HE2  sing N N 257 
PHE CZ  HZ   sing N N 258 
PHE OXT HXT  sing N N 259 
PRO N   CA   sing N N 260 
PRO N   CD   sing N N 261 
PRO N   H    sing N N 262 
PRO CA  C    sing N N 263 
PRO CA  CB   sing N N 264 
PRO CA  HA   sing N N 265 
PRO C   O    doub N N 266 
PRO C   OXT  sing N N 267 
PRO CB  CG   sing N N 268 
PRO CB  HB2  sing N N 269 
PRO CB  HB3  sing N N 270 
PRO CG  CD   sing N N 271 
PRO CG  HG2  sing N N 272 
PRO CG  HG3  sing N N 273 
PRO CD  HD2  sing N N 274 
PRO CD  HD3  sing N N 275 
PRO OXT HXT  sing N N 276 
SER N   CA   sing N N 277 
SER N   H    sing N N 278 
SER N   H2   sing N N 279 
SER CA  C    sing N N 280 
SER CA  CB   sing N N 281 
SER CA  HA   sing N N 282 
SER C   O    doub N N 283 
SER C   OXT  sing N N 284 
SER CB  OG   sing N N 285 
SER CB  HB2  sing N N 286 
SER CB  HB3  sing N N 287 
SER OG  HG   sing N N 288 
SER OXT HXT  sing N N 289 
SO4 S   O1   doub N N 290 
SO4 S   O2   doub N N 291 
SO4 S   O3   sing N N 292 
SO4 S   O4   sing N N 293 
THR N   CA   sing N N 294 
THR N   H    sing N N 295 
THR N   H2   sing N N 296 
THR CA  C    sing N N 297 
THR CA  CB   sing N N 298 
THR CA  HA   sing N N 299 
THR C   O    doub N N 300 
THR C   OXT  sing N N 301 
THR CB  OG1  sing N N 302 
THR CB  CG2  sing N N 303 
THR CB  HB   sing N N 304 
THR OG1 HG1  sing N N 305 
THR CG2 HG21 sing N N 306 
THR CG2 HG22 sing N N 307 
THR CG2 HG23 sing N N 308 
THR OXT HXT  sing N N 309 
TRP N   CA   sing N N 310 
TRP N   H    sing N N 311 
TRP N   H2   sing N N 312 
TRP CA  C    sing N N 313 
TRP CA  CB   sing N N 314 
TRP CA  HA   sing N N 315 
TRP C   O    doub N N 316 
TRP C   OXT  sing N N 317 
TRP CB  CG   sing N N 318 
TRP CB  HB2  sing N N 319 
TRP CB  HB3  sing N N 320 
TRP CG  CD1  doub Y N 321 
TRP CG  CD2  sing Y N 322 
TRP CD1 NE1  sing Y N 323 
TRP CD1 HD1  sing N N 324 
TRP CD2 CE2  doub Y N 325 
TRP CD2 CE3  sing Y N 326 
TRP NE1 CE2  sing Y N 327 
TRP NE1 HE1  sing N N 328 
TRP CE2 CZ2  sing Y N 329 
TRP CE3 CZ3  doub Y N 330 
TRP CE3 HE3  sing N N 331 
TRP CZ2 CH2  doub Y N 332 
TRP CZ2 HZ2  sing N N 333 
TRP CZ3 CH2  sing Y N 334 
TRP CZ3 HZ3  sing N N 335 
TRP CH2 HH2  sing N N 336 
TRP OXT HXT  sing N N 337 
TYR N   CA   sing N N 338 
TYR N   H    sing N N 339 
TYR N   H2   sing N N 340 
TYR CA  C    sing N N 341 
TYR CA  CB   sing N N 342 
TYR CA  HA   sing N N 343 
TYR C   O    doub N N 344 
TYR C   OXT  sing N N 345 
TYR CB  CG   sing N N 346 
TYR CB  HB2  sing N N 347 
TYR CB  HB3  sing N N 348 
TYR CG  CD1  doub Y N 349 
TYR CG  CD2  sing Y N 350 
TYR CD1 CE1  sing Y N 351 
TYR CD1 HD1  sing N N 352 
TYR CD2 CE2  doub Y N 353 
TYR CD2 HD2  sing N N 354 
TYR CE1 CZ   doub Y N 355 
TYR CE1 HE1  sing N N 356 
TYR CE2 CZ   sing Y N 357 
TYR CE2 HE2  sing N N 358 
TYR CZ  OH   sing N N 359 
TYR OH  HH   sing N N 360 
TYR OXT HXT  sing N N 361 
VAL N   CA   sing N N 362 
VAL N   H    sing N N 363 
VAL N   H2   sing N N 364 
VAL CA  C    sing N N 365 
VAL CA  CB   sing N N 366 
VAL CA  HA   sing N N 367 
VAL C   O    doub N N 368 
VAL C   OXT  sing N N 369 
VAL CB  CG1  sing N N 370 
VAL CB  CG2  sing N N 371 
VAL CB  HB   sing N N 372 
VAL CG1 HG11 sing N N 373 
VAL CG1 HG12 sing N N 374 
VAL CG1 HG13 sing N N 375 
VAL CG2 HG21 sing N N 376 
VAL CG2 HG22 sing N N 377 
VAL CG2 HG23 sing N N 378 
VAL OXT HXT  sing N N 379 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute Of Allergy and Infectious Diseases (NIH/NIAID)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           1R01-AI141465 
_pdbx_audit_support.ordinal                1 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   2X87 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 65' 
_space_group.name_Hall        'P 65' 
_space_group.IT_number        170 
_space_group.crystal_system   hexagonal 
_space_group.id               1 
# 
_atom_sites.entry_id                    9BD5 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.010549 
_atom_sites.fract_transf_matrix[1][2]   0.006090 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.012180 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.003681 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C   ? ? 3.54356  2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
CU  ? ? 23.42449 5.47274 ? ? 2.18335  24.96234 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N   ? ? 4.01032  2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O   ? ? 7.96527  ?       ? ? 9.05267  ?        ? ? 0.0 
;1-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O1- ? ? 5.12366  3.84317 ? ? 3.49406  27.47979 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S   ? ? 9.55732  6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . LYS A  1 2   ? 5.98711  42.50084  -32.43602 1.000 61.66648 ? 2   LYS A N   1 
ATOM   2    C  CA  . LYS A  1 2   ? 6.05171  43.04059  -31.08293 1.000 53.99569 ? 2   LYS A CA  1 
ATOM   3    C  C   . LYS A  1 2   ? 7.50212  43.27176  -30.65640 1.000 53.87512 ? 2   LYS A C   1 
ATOM   4    O  O   . LYS A  1 2   ? 8.39937  42.52734  -31.05958 1.000 46.39941 ? 2   LYS A O   1 
ATOM   5    C  CB  . LYS A  1 2   ? 5.34122  42.10209  -30.10053 1.000 53.89267 ? 2   LYS A CB  1 
ATOM   6    C  CG  . LYS A  1 2   ? 5.40075  42.55120  -28.64778 1.000 57.02940 ? 2   LYS A CG  1 
ATOM   7    C  CD  . LYS A  1 2   ? 4.20019  42.06251  -27.85721 1.000 53.13309 ? 2   LYS A CD  1 
ATOM   8    C  CE  . LYS A  1 2   ? 4.32209  42.44460  -26.39104 1.000 46.46149 ? 2   LYS A CE  1 
ATOM   9    N  NZ  . LYS A  1 2   ? 5.47151  41.75708  -25.73697 1.000 30.98237 ? 2   LYS A NZ  1 
ATOM   10   N  N   . LEU A  1 3   ? 7.71038  44.32012  -29.85280 1.000 41.00662 ? 3   LEU A N   1 
ATOM   11   C  CA  . LEU A  1 3   ? 9.01517  44.70412  -29.31877 1.000 32.37182 ? 3   LEU A CA  1 
ATOM   12   C  C   . LEU A  1 3   ? 9.96787  45.14539  -30.42332 1.000 31.26361 ? 3   LEU A C   1 
ATOM   13   O  O   . LEU A  1 3   ? 10.50611 44.31439  -31.16202 1.000 31.68967 ? 3   LEU A O   1 
ATOM   14   C  CB  . LEU A  1 3   ? 9.63437  43.56248  -28.50597 1.000 28.88839 ? 3   LEU A CB  1 
ATOM   15   C  CG  . LEU A  1 3   ? 8.90367  43.17224  -27.21984 1.000 34.79043 ? 3   LEU A CG  1 
ATOM   16   C  CD1 . LEU A  1 3   ? 9.70402  42.14346  -26.43763 1.000 20.51069 ? 3   LEU A CD1 1 
ATOM   17   C  CD2 . LEU A  1 3   ? 8.62275  44.40051  -26.36831 1.000 29.61243 ? 3   LEU A CD2 1 
ATOM   18   N  N   . GLU A  1 4   ? 10.18695 46.45432  -30.53174 1.000 27.64734 ? 4   GLU A N   1 
ATOM   19   C  CA  . GLU A  1 4   ? 11.06924 46.99097  -31.55862 1.000 27.41630 ? 4   GLU A CA  1 
ATOM   20   C  C   . GLU A  1 4   ? 12.50896 46.57066  -31.29137 1.000 31.61188 ? 4   GLU A C   1 
ATOM   21   O  O   . GLU A  1 4   ? 13.01091 46.70756  -30.17141 1.000 27.57469 ? 4   GLU A O   1 
ATOM   22   C  CB  . GLU A  1 4   ? 10.95989 48.51365  -31.60479 1.000 33.39520 ? 4   GLU A CB  1 
ATOM   23   C  CG  . GLU A  1 4   ? 11.77725 49.16457  -32.70668 1.000 31.88187 ? 4   GLU A CG  1 
ATOM   24   C  CD  . GLU A  1 4   ? 11.64643 50.67472  -32.71042 1.000 42.41207 ? 4   GLU A CD  1 
ATOM   25   O  OE1 . GLU A  1 4   ? 11.10793 51.22795  -31.72793 1.000 34.35291 ? 4   GLU A OE1 1 
ATOM   26   O  OE2 . GLU A  1 4   ? 12.07911 51.30885  -33.69626 1.000 49.14181 ? 4   GLU A OE2 1 
ATOM   27   N  N   . LYS A  1 5   ? 13.17371 46.06306  -32.32442 1.000 25.69980 ? 5   LYS A N   1 
ATOM   28   C  CA  . LYS A  1 5   ? 14.52763 45.55652  -32.17489 1.000 22.06112 ? 5   LYS A CA  1 
ATOM   29   C  C   . LYS A  1 5   ? 15.53779 46.69457  -32.09912 1.000 24.81214 ? 5   LYS A C   1 
ATOM   30   O  O   . LYS A  1 5   ? 15.35294 47.76250  -32.69055 1.000 28.58627 ? 5   LYS A O   1 
ATOM   31   C  CB  . LYS A  1 5   ? 14.89091 44.63088  -33.33807 1.000 20.13412 ? 5   LYS A CB  1 
ATOM   32   C  CG  . LYS A  1 5   ? 14.04913 43.36871  -33.42913 1.000 20.94749 ? 5   LYS A CG  1 
ATOM   33   C  CD  . LYS A  1 5   ? 14.53507 42.46065  -34.55138 1.000 23.26002 ? 5   LYS A CD  1 
ATOM   34   C  CE  . LYS A  1 5   ? 14.24006 43.04906  -35.92376 1.000 21.52172 ? 5   LYS A CE  1 
ATOM   35   N  NZ  . LYS A  1 5   ? 12.77841 43.10233  -36.19805 1.000 21.57358 ? 5   LYS A NZ  1 
ATOM   36   N  N   . PHE A  1 6   ? 16.61069 46.45196  -31.34080 1.000 22.30704 ? 6   PHE A N   1 
ATOM   37   C  CA  . PHE A  1 6   ? 17.82782 47.26675  -31.37983 1.000 22.08135 ? 6   PHE A CA  1 
ATOM   38   C  C   . PHE A  1 6   ? 17.58229 48.67772  -30.84030 1.000 24.24952 ? 6   PHE A C   1 
ATOM   39   O  O   . PHE A  1 6   ? 17.98542 49.67427  -31.44206 1.000 25.20469 ? 6   PHE A O   1 
ATOM   40   C  CB  . PHE A  1 6   ? 18.40734 47.30599  -32.79766 1.000 19.74535 ? 6   PHE A CB  1 
ATOM   41   C  CG  . PHE A  1 6   ? 18.40443 45.96828  -33.48750 1.000 21.52586 ? 6   PHE A CG  1 
ATOM   42   C  CD1 . PHE A  1 6   ? 18.79616 44.82147  -32.81238 1.000 21.32065 ? 6   PHE A CD1 1 
ATOM   43   C  CD2 . PHE A  1 6   ? 17.98892 45.85391  -34.80311 1.000 24.22329 ? 6   PHE A CD2 1 
ATOM   44   C  CE1 . PHE A  1 6   ? 18.78604 43.59096  -33.44090 1.000 18.51946 ? 6   PHE A CE1 1 
ATOM   45   C  CE2 . PHE A  1 6   ? 17.97703 44.62390  -35.43846 1.000 22.90510 ? 6   PHE A CE2 1 
ATOM   46   C  CZ  . PHE A  1 6   ? 18.37567 43.49227  -34.75638 1.000 20.55503 ? 6   PHE A CZ  1 
ATOM   47   N  N   . VAL A  1 7   ? 16.92279 48.75318  -29.68725 1.000 19.20064 ? 7   VAL A N   1 
ATOM   48   C  CA  . VAL A  1 7   ? 16.70769 50.02692  -29.01443 1.000 18.58082 ? 7   VAL A CA  1 
ATOM   49   C  C   . VAL A  1 7   ? 17.38626 50.10525  -27.65392 1.000 20.70352 ? 7   VAL A C   1 
ATOM   50   O  O   . VAL A  1 7   ? 17.59239 51.22055  -27.14788 1.000 20.49850 ? 7   VAL A O   1 
ATOM   51   C  CB  . VAL A  1 7   ? 15.20312 50.33858  -28.87542 1.000 17.54809 ? 7   VAL A CB  1 
ATOM   52   C  CG1 . VAL A  1 7   ? 14.58819 50.58631  -30.24351 1.000 21.15413 ? 7   VAL A CG1 1 
ATOM   53   C  CG2 . VAL A  1 7   ? 14.48887 49.20447  -28.16029 1.000 23.93796 ? 7   VAL A CG2 1 
ATOM   54   N  N   . ASP A  1 8   ? 17.74400 48.98304  -27.03779 1.000 23.16645 ? 8   ASP A N   1 
ATOM   55   C  CA  . ASP A  1 8   ? 18.47123 48.97707  -25.77776 1.000 20.54437 ? 8   ASP A CA  1 
ATOM   56   C  C   . ASP A  1 8   ? 19.93871 48.64892  -26.02201 1.000 20.96435 ? 8   ASP A C   1 
ATOM   57   O  O   . ASP A  1 8   ? 20.27833 47.87120  -26.91644 1.000 25.74164 ? 8   ASP A O   1 
ATOM   58   C  CB  . ASP A  1 8   ? 17.87342 47.96281  -24.80132 1.000 19.23315 ? 8   ASP A CB  1 
ATOM   59   C  CG  . ASP A  1 8   ? 16.42162 48.24573  -24.47887 1.000 22.53841 ? 8   ASP A CG  1 
ATOM   60   O  OD1 . ASP A  1 8   ? 15.55134 47.92587  -25.31521 1.000 22.58896 ? 8   ASP A OD1 1 
ATOM   61   O  OD2 . ASP A  1 8   ? 16.15019 48.78436  -23.38546 1.000 28.24747 ? 8   ASP A OD2 1 
ATOM   62   N  N   . LYS A  1 9   ? 20.80906 49.24678  -25.21453 1.000 19.68326 ? 9   LYS A N   1 
ATOM   63   C  CA  . LYS A  1 9   ? 22.23668 49.00139  -25.34722 1.000 19.12920 ? 9   LYS A CA  1 
ATOM   64   C  C   . LYS A  1 9   ? 22.62263 47.69952  -24.65526 1.000 21.04603 ? 9   LYS A C   1 
ATOM   65   O  O   . LYS A  1 9   ? 22.02659 47.30306  -23.64963 1.000 18.92925 ? 9   LYS A O   1 
ATOM   66   C  CB  . LYS A  1 9   ? 23.04243 50.16806  -24.77385 1.000 22.17298 ? 9   LYS A CB  1 
ATOM   67   C  CG  . LYS A  1 9   ? 22.69810 51.50237  -25.41472 1.000 32.17808 ? 9   LYS A CG  1 
ATOM   68   C  CD  . LYS A  1 9   ? 23.82643 52.51660  -25.30831 1.000 38.33307 ? 9   LYS A CD  1 
ATOM   69   C  CE  . LYS A  1 9   ? 23.96860 53.05590  -23.89689 1.000 44.31766 ? 9   LYS A CE  1 
ATOM   70   N  NZ  . LYS A  1 9   ? 24.65335 54.38054  -23.88793 1.000 46.66391 ? 9   LYS A NZ  1 
ATOM   71   N  N   . LEU A  1 10  ? 23.62704 47.03473  -25.21147 1.000 21.10946 ? 10  LEU A N   1 
ATOM   72   C  CA  . LEU A  1 10  ? 24.05794 45.73372  -24.70947 1.000 16.77978 ? 10  LEU A CA  1 
ATOM   73   C  C   . LEU A  1 10  ? 24.63774 45.86383  -23.30755 1.000 16.40688 ? 10  LEU A C   1 
ATOM   74   O  O   . LEU A  1 10  ? 25.65766 46.54252  -23.13017 1.000 22.55850 ? 10  LEU A O   1 
ATOM   75   C  CB  . LEU A  1 10  ? 25.09300 45.12407  -25.64860 1.000 16.38034 ? 10  LEU A CB  1 
ATOM   76   C  CG  . LEU A  1 10  ? 25.68096 43.79033  -25.18658 1.000 19.88363 ? 10  LEU A CG  1 
ATOM   77   C  CD1 . LEU A  1 10  ? 24.59283 42.73035  -25.11713 1.000 18.72505 ? 10  LEU A CD1 1 
ATOM   78   C  CD2 . LEU A  1 10  ? 26.81215 43.34852  -26.10013 1.000 18.48743 ? 10  LEU A CD2 1 
ATOM   79   N  N   . PRO A  1 11  ? 24.03998 45.24037  -22.29493 1.000 16.49185 ? 11  PRO A N   1 
ATOM   80   C  CA  . PRO A  1 11  ? 24.60259 45.32462  -20.94369 1.000 15.31814 ? 11  PRO A CA  1 
ATOM   81   C  C   . PRO A  1 11  ? 25.80913 44.41312  -20.79129 1.000 20.02891 ? 11  PRO A C   1 
ATOM   82   O  O   . PRO A  1 11  ? 25.87239 43.32466  -21.36770 1.000 18.67122 ? 11  PRO A O   1 
ATOM   83   C  CB  . PRO A  1 11  ? 23.44618 44.86228  -20.04350 1.000 11.13663 ? 11  PRO A CB  1 
ATOM   84   C  CG  . PRO A  1 11  ? 22.23460 44.75031  -20.94828 1.000 13.76933 ? 11  PRO A CG  1 
ATOM   85   C  CD  . PRO A  1 11  ? 22.77656 44.49041  -22.31348 1.000 16.40575 ? 11  PRO A CD  1 
ATOM   86   N  N   . ILE A  1 12  ? 26.77570 44.87197  -20.01066 1.000 17.92438 ? 12  ILE A N   1 
ATOM   87   C  CA  . ILE A  1 12  ? 27.93530 44.07316  -19.63119 1.000 16.88648 ? 12  ILE A CA  1 
ATOM   88   C  C   . ILE A  1 12  ? 27.79966 43.74546  -18.14875 1.000 18.47591 ? 12  ILE A C   1 
ATOM   89   O  O   . ILE A  1 12  ? 27.77599 44.66512  -17.32022 1.000 18.44669 ? 12  ILE A O   1 
ATOM   90   C  CB  . ILE A  1 12  ? 29.25527 44.80669  -19.91651 1.000 26.64799 ? 12  ILE A CB  1 
ATOM   91   C  CG1 . ILE A  1 12  ? 29.33002 45.22129  -21.38777 1.000 20.75992 ? 12  ILE A CG1 1 
ATOM   92   C  CG2 . ILE A  1 12  ? 30.44169 43.92518  -19.54812 1.000 17.73710 ? 12  ILE A CG2 1 
ATOM   93   C  CD1 . ILE A  1 12  ? 29.29674 44.05897  -22.35616 1.000 13.81461 ? 12  ILE A CD1 1 
ATOM   94   N  N   . PRO A  1 13  ? 27.68298 42.47376  -17.77098 1.000 25.59185 ? 13  PRO A N   1 
ATOM   95   C  CA  . PRO A  1 13  ? 27.58794 42.13474  -16.34440 1.000 18.70436 ? 13  PRO A CA  1 
ATOM   96   C  C   . PRO A  1 13  ? 28.83717 42.57564  -15.59524 1.000 20.08441 ? 13  PRO A C   1 
ATOM   97   O  O   . PRO A  1 13  ? 29.96303 42.35542  -16.04794 1.000 23.99994 ? 13  PRO A O   1 
ATOM   98   C  CB  . PRO A  1 13  ? 27.43921 40.60866  -16.35158 1.000 17.52437 ? 13  PRO A CB  1 
ATOM   99   C  CG  . PRO A  1 13  ? 26.92921 40.27845  -17.72192 1.000 20.60757 ? 13  PRO A CG  1 
ATOM   100  C  CD  . PRO A  1 13  ? 27.54742 41.28972  -18.63609 1.000 18.39418 ? 13  PRO A CD  1 
ATOM   101  N  N   . LYS A  1 14  ? 28.63040 43.21651  -14.44737 1.000 21.61835 ? 14  LYS A N   1 
ATOM   102  C  CA  . LYS A  1 14  ? 29.75358 43.67226  -13.64203 1.000 19.49020 ? 14  LYS A CA  1 
ATOM   103  C  C   . LYS A  1 14  ? 30.54132 42.48785  -13.09809 1.000 16.92431 ? 14  LYS A C   1 
ATOM   104  O  O   . LYS A  1 14  ? 29.98948 41.42478  -12.79930 1.000 18.01762 ? 14  LYS A O   1 
ATOM   105  C  CB  . LYS A  1 14  ? 29.27586 44.54706  -12.48291 1.000 19.96713 ? 14  LYS A CB  1 
ATOM   106  C  CG  . LYS A  1 14  ? 28.81639 45.94170  -12.88805 1.000 25.14641 ? 14  LYS A CG  1 
ATOM   107  C  CD  . LYS A  1 14  ? 28.27017 46.70838  -11.69150 1.000 26.26003 ? 14  LYS A CD  1 
ATOM   108  C  CE  . LYS A  1 14  ? 27.49351 45.77787  -10.76744 1.000 45.45940 ? 14  LYS A CE  1 
ATOM   109  N  NZ  . LYS A  1 14  ? 26.51042 46.49082  -9.89811  1.000 43.92002 ? 14  LYS A NZ  1 
ATOM   110  N  N   . VAL A  1 15  ? 31.85258 42.68370  -12.97428 1.000 19.29082 ? 15  VAL A N   1 
ATOM   111  C  CA  . VAL A  1 15  ? 32.71088 41.65657  -12.40184 1.000 16.69413 ? 15  VAL A CA  1 
ATOM   112  C  C   . VAL A  1 15  ? 32.49404 41.60636  -10.89652 1.000 19.44471 ? 15  VAL A C   1 
ATOM   113  O  O   . VAL A  1 15  ? 32.57743 42.62999  -10.20486 1.000 19.37631 ? 15  VAL A O   1 
ATOM   114  C  CB  . VAL A  1 15  ? 34.18041 41.92822  -12.75041 1.000 15.17822 ? 15  VAL A CB  1 
ATOM   115  C  CG1 . VAL A  1 15  ? 35.08079 40.92102  -12.05476 1.000 16.72131 ? 15  VAL A CG1 1 
ATOM   116  C  CG2 . VAL A  1 15  ? 34.37901 41.87955  -14.25728 1.000 17.40954 ? 15  VAL A CG2 1 
ATOM   117  N  N   . LEU A  1 16  ? 32.20692 40.41372  -10.38363 1.000 17.13171 ? 16  LEU A N   1 
ATOM   118  C  CA  . LEU A  1 16  ? 31.89947 40.25989  -8.96928  1.000 17.75199 ? 16  LEU A CA  1 
ATOM   119  C  C   . LEU A  1 16  ? 33.13537 40.50343  -8.11362  1.000 15.67135 ? 16  LEU A C   1 
ATOM   120  O  O   . LEU A  1 16  ? 34.23896 40.06199  -8.44391  1.000 18.47008 ? 16  LEU A O   1 
ATOM   121  C  CB  . LEU A  1 16  ? 31.34830 38.86226  -8.69728  1.000 24.29714 ? 16  LEU A CB  1 
ATOM   122  C  CG  . LEU A  1 16  ? 30.87601 38.60559  -7.26581  1.000 21.12370 ? 16  LEU A CG  1 
ATOM   123  C  CD1 . LEU A  1 16  ? 29.75824 39.56580  -6.89509  1.000 17.52033 ? 16  LEU A CD1 1 
ATOM   124  C  CD2 . LEU A  1 16  ? 30.42412 37.16943  -7.10260  1.000 21.03835 ? 16  LEU A CD2 1 
ATOM   125  N  N   . LYS A  1 17  ? 32.94211 41.21041  -7.00577  1.000 23.00569 ? 17  LYS A N   1 
ATOM   126  C  CA  . LYS A  1 17  ? 34.01373 41.46425  -6.05614  1.000 22.53017 ? 17  LYS A CA  1 
ATOM   127  C  C   . LYS A  1 17  ? 33.89832 40.52693  -4.86207  1.000 22.21664 ? 17  LYS A C   1 
ATOM   128  O  O   . LYS A  1 17  ? 32.79800 40.32266  -4.33748  1.000 26.89202 ? 17  LYS A O   1 
ATOM   129  C  CB  . LYS A  1 17  ? 33.97744 42.91375  -5.57002  1.000 18.89511 ? 17  LYS A CB  1 
ATOM   130  C  CG  . LYS A  1 17  ? 34.49469 43.91295  -6.58836  1.000 26.26259 ? 17  LYS A CG  1 
ATOM   131  C  CD  . LYS A  1 17  ? 34.48368 45.32671  -6.03623  1.000 28.15229 ? 17  LYS A CD  1 
ATOM   132  C  CE  . LYS A  1 17  ? 35.36268 46.24724  -6.86727  1.000 29.79434 ? 17  LYS A CE  1 
ATOM   133  N  NZ  . LYS A  1 17  ? 36.79135 45.82149  -6.82535  1.000 37.02288 ? 17  LYS A NZ  1 
ATOM   134  N  N   . PRO A  1 18  ? 35.00522 39.93750  -4.42363  1.000 20.74167 ? 18  PRO A N   1 
ATOM   135  C  CA  . PRO A  1 18  ? 34.95102 38.99757  -3.30154  1.000 21.00375 ? 18  PRO A CA  1 
ATOM   136  C  C   . PRO A  1 18  ? 34.81218 39.71332  -1.96628  1.000 22.31054 ? 18  PRO A C   1 
ATOM   137  O  O   . PRO A  1 18  ? 35.16100 40.88488  -1.81178  1.000 23.22650 ? 18  PRO A O   1 
ATOM   138  C  CB  . PRO A  1 18  ? 36.29320 38.26364  -3.39448  1.000 20.36449 ? 18  PRO A CB  1 
ATOM   139  C  CG  . PRO A  1 18  ? 37.20737 39.26397  -4.01728  1.000 21.17339 ? 18  PRO A CG  1 
ATOM   140  C  CD  . PRO A  1 18  ? 36.36363 40.05964  -4.98201  1.000 19.00070 ? 18  PRO A CD  1 
ATOM   141  N  N   . HIS A  1 19  ? 34.27947 38.97510  -0.98939  1.000 19.16965 ? 19  HIS A N   1 
ATOM   142  C  CA  . HIS A  1 19  ? 34.18364 39.51205  0.36398   1.000 19.66289 ? 19  HIS A CA  1 
ATOM   143  C  C   . HIS A  1 19  ? 35.55068 39.55573  1.03552   1.000 19.86042 ? 19  HIS A C   1 
ATOM   144  O  O   . HIS A  1 19  ? 35.84905 40.48989  1.78795   1.000 26.21578 ? 19  HIS A O   1 
ATOM   145  C  CB  . HIS A  1 19  ? 33.20184 38.68488  1.19533   1.000 20.20932 ? 19  HIS A CB  1 
ATOM   146  C  CG  . HIS A  1 19  ? 31.76404 38.92530  0.85212   1.000 21.99176 ? 19  HIS A CG  1 
ATOM   147  N  ND1 . HIS A  1 19  ? 31.36664 39.49043  -0.34059  1.000 23.48814 ? 19  HIS A ND1 1 
ATOM   148  C  CD2 . HIS A  1 19  ? 30.62866 38.68115  1.54852   1.000 19.75880 ? 19  HIS A CD2 1 
ATOM   149  C  CE1 . HIS A  1 19  ? 30.04874 39.58065  -0.36571  1.000 18.59752 ? 19  HIS A CE1 1 
ATOM   150  N  NE2 . HIS A  1 19  ? 29.57675 39.09746  0.76915   1.000 22.42184 ? 19  HIS A NE2 1 
ATOM   151  N  N   . SER A  1 20  ? 36.39410 38.56000  0.77318   1.000 17.76806 ? 20  SER A N   1 
ATOM   152  C  CA  . SER A  1 20  ? 37.72663 38.50257  1.35447   1.000 17.59015 ? 20  SER A CA  1 
ATOM   153  C  C   . SER A  1 20  ? 38.65518 37.77519  0.39335   1.000 23.50952 ? 20  SER A C   1 
ATOM   154  O  O   . SER A  1 20  ? 38.26178 36.78685  -0.23199  1.000 24.24230 ? 20  SER A O   1 
ATOM   155  C  CB  . SER A  1 20  ? 37.71393 37.80040  2.71693   1.000 24.54902 ? 20  SER A CB  1 
ATOM   156  O  OG  . SER A  1 20  ? 38.99661 37.83156  3.31993   1.000 31.73422 ? 20  SER A OG  1 
ATOM   157  N  N   . LYS A  1 21  ? 39.88717 38.26895  0.28358   1.000 28.62325 ? 21  LYS A N   1 
ATOM   158  C  CA  . LYS A  1 21  ? 40.87302 37.71272  -0.63649  1.000 23.91908 ? 21  LYS A CA  1 
ATOM   159  C  C   . LYS A  1 21  ? 42.21425 37.64017  0.07391   1.000 24.96056 ? 21  LYS A C   1 
ATOM   160  O  O   . LYS A  1 21  ? 42.74926 38.66898  0.49739   1.000 28.66025 ? 21  LYS A O   1 
ATOM   161  C  CB  . LYS A  1 21  ? 40.98344 38.56341  -1.90648  1.000 23.39373 ? 21  LYS A CB  1 
ATOM   162  C  CG  . LYS A  1 21  ? 41.72750 37.89815  -3.05744  1.000 19.05720 ? 21  LYS A CG  1 
ATOM   163  C  CD  . LYS A  1 21  ? 41.90268 38.86781  -4.21841  1.000 22.64238 ? 21  LYS A CD  1 
ATOM   164  C  CE  . LYS A  1 21  ? 42.15773 38.14298  -5.53202  1.000 18.22767 ? 21  LYS A CE  1 
ATOM   165  N  NZ  . LYS A  1 21  ? 43.38960 37.30930  -5.49759  1.000 24.64206 ? 21  LYS A NZ  1 
ATOM   166  N  N   . SER A  1 22  ? 42.75276 36.43165  0.20475   1.000 31.88526 ? 22  SER A N   1 
ATOM   167  C  CA  . SER A  1 22  ? 44.05922 36.20764  0.80656   1.000 38.42164 ? 22  SER A CA  1 
ATOM   168  C  C   . SER A  1 22  ? 44.89233 35.34779  -0.13470  1.000 37.27543 ? 22  SER A C   1 
ATOM   169  O  O   . SER A  1 22  ? 44.43002 34.92563  -1.19866  1.000 43.79573 ? 22  SER A O   1 
ATOM   170  C  CB  . SER A  1 22  ? 43.93413 35.54136  2.18307   1.000 37.30014 ? 22  SER A CB  1 
ATOM   171  O  OG  . SER A  1 22  ? 43.51737 34.19236  2.05908   1.000 38.99819 ? 22  SER A OG  1 
ATOM   172  N  N   . LYS A  1 23  ? 46.14075 35.08998  0.25973   1.000 43.69734 ? 23  LYS A N   1 
ATOM   173  C  CA  . LYS A  1 23  ? 46.96560 34.15734  -0.49751  1.000 42.98968 ? 23  LYS A CA  1 
ATOM   174  C  C   . LYS A  1 23  ? 46.49089 32.72051  -0.33614  1.000 44.92304 ? 23  LYS A C   1 
ATOM   175  O  O   . LYS A  1 23  ? 46.75161 31.89231  -1.21509  1.000 40.04181 ? 23  LYS A O   1 
ATOM   176  C  CB  . LYS A  1 23  ? 48.43161 34.28879  -0.08111  1.000 43.14275 ? 23  LYS A CB  1 
ATOM   177  C  CG  . LYS A  1 23  ? 49.18437 35.35813  -0.85678  1.000 52.26877 ? 23  LYS A CG  1 
ATOM   178  C  CD  . LYS A  1 23  ? 50.50438 35.72243  -0.19724  1.000 62.59762 ? 23  LYS A CD  1 
ATOM   179  C  CE  . LYS A  1 23  ? 50.28295 36.56372  1.05039   1.000 58.65770 ? 23  LYS A CE  1 
ATOM   180  N  NZ  . LYS A  1 23  ? 49.35492 37.70769  0.79622   1.000 37.54219 ? 23  LYS A NZ  1 
ATOM   181  N  N   . GLU A  1 24  ? 45.79327 32.41117  0.75819   1.000 49.17130 ? 24  GLU A N   1 
ATOM   182  C  CA  . GLU A  1 24  ? 45.19401 31.08994  0.90837   1.000 47.23233 ? 24  GLU A CA  1 
ATOM   183  C  C   . GLU A  1 24  ? 43.99189 30.92506  -0.01289  1.000 50.09066 ? 24  GLU A C   1 
ATOM   184  O  O   . GLU A  1 24  ? 43.92356 29.97448  -0.80132  1.000 44.93449 ? 24  GLU A O   1 
ATOM   185  C  CB  . GLU A  1 24  ? 44.77286 30.86498  2.36117   1.000 48.47187 ? 24  GLU A CB  1 
ATOM   186  C  CG  . GLU A  1 24  ? 45.90446 30.85269  3.36875   1.000 59.12261 ? 24  GLU A CG  1 
ATOM   187  C  CD  . GLU A  1 24  ? 45.41900 31.14986  4.77534   1.000 70.20986 ? 24  GLU A CD  1 
ATOM   188  O  OE1 . GLU A  1 24  ? 44.47272 31.95407  4.91951   1.000 62.67400 ? 24  GLU A OE1 1 
ATOM   189  O  OE2 . GLU A  1 24  ? 45.97742 30.57772  5.73494   1.000 65.66817 ? 24  GLU A OE2 1 
ATOM   190  N  N   . MET A  1 25  ? 43.03663 31.84968  0.06660   1.000 44.54322 ? 25  MET A N   1 
ATOM   191  C  CA  . MET A  1 25  ? 41.72638 31.63604  -0.52527  1.000 35.63198 ? 25  MET A CA  1 
ATOM   192  C  C   . MET A  1 25  ? 41.12992 32.96737  -0.95818  1.000 29.24022 ? 25  MET A C   1 
ATOM   193  O  O   . MET A  1 25  ? 41.46343 34.02223  -0.41202  1.000 27.55022 ? 25  MET A O   1 
ATOM   194  C  CB  . MET A  1 25  ? 40.80033 30.93421  0.47597   1.000 32.00016 ? 25  MET A CB  1 
ATOM   195  C  CG  . MET A  1 25  ? 39.59351 30.24393  -0.12567  1.000 35.76100 ? 25  MET A CG  1 
ATOM   196  S  SD  . MET A  1 25  ? 38.65333 29.38776  1.15309   1.000 64.21536 ? 25  MET A SD  1 
ATOM   197  C  CE  . MET A  1 25  ? 38.19130 30.76472  2.20424   1.000 28.04922 ? 25  MET A CE  1 
ATOM   198  N  N   . THR A  1 26  ? 40.24502 32.90432  -1.95230  1.000 26.98490 ? 26  THR A N   1 
ATOM   199  C  CA  . THR A  1 26  ? 39.44017 34.04305  -2.38565  1.000 21.26914 ? 26  THR A CA  1 
ATOM   200  C  C   . THR A  1 26  ? 37.98049 33.67766  -2.14977  1.000 25.22526 ? 26  THR A C   1 
ATOM   201  O  O   . THR A  1 26  ? 37.44809 32.77714  -2.80782  1.000 22.39917 ? 26  THR A O   1 
ATOM   202  C  CB  . THR A  1 26  ? 39.69577 34.38588  -3.85325  1.000 19.46755 ? 26  THR A CB  1 
ATOM   203  O  OG1 . THR A  1 26  ? 41.08522 34.67772  -4.04343  1.000 20.34643 ? 26  THR A OG1 1 
ATOM   204  C  CG2 . THR A  1 26  ? 38.87466 35.59736  -4.26697  1.000 20.08337 ? 26  THR A CG2 1 
ATOM   205  N  N   . TYR A  1 27  ? 37.33797 34.36955  -1.21312  1.000 19.41449 ? 27  TYR A N   1 
ATOM   206  C  CA  . TYR A  1 27  ? 36.01979 33.98938  -0.72384  1.000 17.57092 ? 27  TYR A CA  1 
ATOM   207  C  C   . TYR A  1 27  ? 34.94791 34.90908  -1.29459  1.000 18.55278 ? 27  TYR A C   1 
ATOM   208  O  O   . TYR A  1 27  ? 35.05264 36.13575  -1.18894  1.000 17.48535 ? 27  TYR A O   1 
ATOM   209  C  CB  . TYR A  1 27  ? 35.98947 34.02270  0.80434   1.000 20.00605 ? 27  TYR A CB  1 
ATOM   210  C  CG  . TYR A  1 27  ? 34.64337 33.69310  1.40157   1.000 21.72674 ? 27  TYR A CG  1 
ATOM   211  C  CD1 . TYR A  1 27  ? 34.14271 32.39801  1.36328   1.000 21.12206 ? 27  TYR A CD1 1 
ATOM   212  C  CD2 . TYR A  1 27  ? 33.87650 34.67518  2.01336   1.000 21.13883 ? 27  TYR A CD2 1 
ATOM   213  C  CE1 . TYR A  1 27  ? 32.91120 32.09227  1.91191   1.000 19.68353 ? 27  TYR A CE1 1 
ATOM   214  C  CE2 . TYR A  1 27  ? 32.64654 34.37915  2.56575   1.000 18.49928 ? 27  TYR A CE2 1 
ATOM   215  C  CZ  . TYR A  1 27  ? 32.16854 33.08701  2.51190   1.000 20.08682 ? 27  TYR A CZ  1 
ATOM   216  O  OH  . TYR A  1 27  ? 30.94381 32.78862  3.06081   1.000 22.12293 ? 27  TYR A OH  1 
ATOM   217  N  N   . TYR A  1 28  ? 33.91799 34.30908  -1.88916  1.000 19.69004 ? 28  TYR A N   1 
ATOM   218  C  CA  . TYR A  1 28  ? 32.78266 35.02442  -2.45019  1.000 16.69611 ? 28  TYR A CA  1 
ATOM   219  C  C   . TYR A  1 28  ? 31.50415 34.63568  -1.71803  1.000 18.13828 ? 28  TYR A C   1 
ATOM   220  O  O   . TYR A  1 28  ? 31.40603 33.56137  -1.11832  1.000 19.07450 ? 28  TYR A O   1 
ATOM   221  C  CB  . TYR A  1 28  ? 32.60832 34.72557  -3.94639  1.000 15.53058 ? 28  TYR A CB  1 
ATOM   222  C  CG  . TYR A  1 28  ? 33.67286 35.29803  -4.85339  1.000 15.83478 ? 28  TYR A CG  1 
ATOM   223  C  CD1 . TYR A  1 28  ? 34.81650 34.57232  -5.16017  1.000 16.54831 ? 28  TYR A CD1 1 
ATOM   224  C  CD2 . TYR A  1 28  ? 33.52057 36.55369  -5.42592  1.000 15.92617 ? 28  TYR A CD2 1 
ATOM   225  C  CE1 . TYR A  1 28  ? 35.78541 35.08876  -5.99958  1.000 19.79497 ? 28  TYR A CE1 1 
ATOM   226  C  CE2 . TYR A  1 28  ? 34.48373 37.07859  -6.26609  1.000 17.63357 ? 28  TYR A CE2 1 
ATOM   227  C  CZ  . TYR A  1 28  ? 35.61408 36.34332  -6.54929  1.000 19.67123 ? 28  TYR A CZ  1 
ATOM   228  O  OH  . TYR A  1 28  ? 36.57536 36.86432  -7.38567  1.000 16.06086 ? 28  TYR A OH  1 
ATOM   229  N  N   . GLU A  1 29  ? 30.51552 35.52575  -1.78438  1.000 17.77291 ? 29  GLU A N   1 
ATOM   230  C  CA  . GLU A  1 29  ? 29.16977 35.24256  -1.29722  1.000 16.04618 ? 29  GLU A CA  1 
ATOM   231  C  C   . GLU A  1 29  ? 28.17151 35.76095  -2.31760  1.000 18.61694 ? 29  GLU A C   1 
ATOM   232  O  O   . GLU A  1 29  ? 28.19290 36.94631  -2.66319  1.000 19.47577 ? 29  GLU A O   1 
ATOM   233  C  CB  . GLU A  1 29  ? 28.91448 35.87694  0.07147   1.000 15.76105 ? 29  GLU A CB  1 
ATOM   234  C  CG  . GLU A  1 29  ? 29.54412 35.11911  1.21523   1.000 22.72580 ? 29  GLU A CG  1 
ATOM   235  C  CD  . GLU A  1 29  ? 29.00320 35.53934  2.56405   1.000 24.21229 ? 29  GLU A CD  1 
ATOM   236  O  OE1 . GLU A  1 29  ? 27.98801 36.26800  2.60399   1.000 26.09987 ? 29  GLU A OE1 1 
ATOM   237  O  OE2 . GLU A  1 29  ? 29.59686 35.13679  3.58508   1.000 20.98519 ? 29  GLU A OE2 1 
ATOM   238  N  N   . VAL A  1 30  ? 27.30701 34.87333  -2.80075  1.000 16.63209 ? 30  VAL A N   1 
ATOM   239  C  CA  . VAL A  1 30  ? 26.29923 35.20566  -3.79867  1.000 16.27928 ? 30  VAL A CA  1 
ATOM   240  C  C   . VAL A  1 30  ? 24.94533 34.76031  -3.26788  1.000 19.96535 ? 30  VAL A C   1 
ATOM   241  O  O   . VAL A  1 30  ? 24.81210 33.64227  -2.75674  1.000 19.29889 ? 30  VAL A O   1 
ATOM   242  C  CB  . VAL A  1 30  ? 26.59872 34.54066  -5.15592  1.000 13.06279 ? 30  VAL A CB  1 
ATOM   243  C  CG1 . VAL A  1 30  ? 25.55768 34.93772  -6.18200  1.000 13.33929 ? 30  VAL A CG1 1 
ATOM   244  C  CG2 . VAL A  1 30  ? 27.99186 34.91554  -5.63435  1.000 12.14128 ? 30  VAL A CG2 1 
ATOM   245  N  N   . THR A  1 31  ? 23.94666 35.63167  -3.38425  1.000 17.03139 ? 31  THR A N   1 
ATOM   246  C  CA  . THR A  1 31  ? 22.60761 35.36319  -2.88194  1.000 23.46327 ? 31  THR A CA  1 
ATOM   247  C  C   . THR A  1 31  ? 21.62365 35.29800  -4.04115  1.000 23.97581 ? 31  THR A C   1 
ATOM   248  O  O   . THR A  1 31  ? 21.68404 36.11344  -4.96678  1.000 23.42240 ? 31  THR A O   1 
ATOM   249  C  CB  . THR A  1 31  ? 22.15951 36.43828  -1.88557  1.000 26.36712 ? 31  THR A CB  1 
ATOM   250  O  OG1 . THR A  1 31  ? 21.77265 37.61862  -2.59892  1.000 32.84827 ? 31  THR A OG1 1 
ATOM   251  C  CG2 . THR A  1 31  ? 23.29377 36.78539  -0.93125  1.000 18.74578 ? 31  THR A CG2 1 
ATOM   252  N  N   . MET A  1 32  ? 20.71944 34.32326  -3.98399  1.000 20.88500 ? 32  MET A N   1 
ATOM   253  C  CA  . MET A  1 32  ? 19.66477 34.17031  -4.98047  1.000 21.02722 ? 32  MET A CA  1 
ATOM   254  C  C   . MET A  1 32  ? 18.43141 34.91926  -4.49133  1.000 24.69921 ? 32  MET A C   1 
ATOM   255  O  O   . MET A  1 32  ? 17.80045 34.51661  -3.50845  1.000 22.56073 ? 32  MET A O   1 
ATOM   256  C  CB  . MET A  1 32  ? 19.35860 32.69439  -5.21703  1.000 18.13833 ? 32  MET A CB  1 
ATOM   257  C  CG  . MET A  1 32  ? 20.47855 31.93714  -5.90253  1.000 21.29324 ? 32  MET A CG  1 
ATOM   258  S  SD  . MET A  1 32  ? 20.59465 30.22477  -5.35311  1.000 20.91819 ? 32  MET A SD  1 
ATOM   259  C  CE  . MET A  1 32  ? 20.64329 29.37443  -6.93183  1.000 24.20574 ? 32  MET A CE  1 
ATOM   260  N  N   . LYS A  1 33  ? 18.08759 36.00705  -5.17374  1.000 24.11731 ? 33  LYS A N   1 
ATOM   261  C  CA  . LYS A  1 33  ? 16.99515 36.87153  -4.75925  1.000 23.73906 ? 33  LYS A CA  1 
ATOM   262  C  C   . LYS A  1 33  ? 15.97737 37.01495  -5.88223  1.000 22.41312 ? 33  LYS A C   1 
ATOM   263  O  O   . LYS A  1 33  ? 16.31938 36.95195  -7.06739  1.000 17.70562 ? 33  LYS A O   1 
ATOM   264  C  CB  . LYS A  1 33  ? 17.51566 38.25663  -4.34469  1.000 23.85165 ? 33  LYS A CB  1 
ATOM   265  C  CG  . LYS A  1 33  ? 18.72527 38.20089  -3.42316  1.000 27.11340 ? 33  LYS A CG  1 
ATOM   266  C  CD  . LYS A  1 33  ? 18.84459 39.44668  -2.55352  1.000 28.50323 ? 33  LYS A CD  1 
ATOM   267  C  CE  . LYS A  1 33  ? 19.42233 40.62682  -3.32123  1.000 37.89792 ? 33  LYS A CE  1 
ATOM   268  N  NZ  . LYS A  1 33  ? 20.73414 41.07011  -2.76446  1.000 34.29285 ? 33  LYS A NZ  1 
ATOM   269  N  N   . GLU A  1 34  ? 14.71782 37.19527  -5.49388  1.000 22.56061 ? 34  GLU A N   1 
ATOM   270  C  CA  . GLU A  1 34  ? 13.65516 37.51613  -6.43420  1.000 20.76940 ? 34  GLU A CA  1 
ATOM   271  C  C   . GLU A  1 34  ? 13.55265 39.02797  -6.58031  1.000 23.59221 ? 34  GLU A C   1 
ATOM   272  O  O   . GLU A  1 34  ? 13.66072 39.76646  -5.59729  1.000 25.62208 ? 34  GLU A O   1 
ATOM   273  C  CB  . GLU A  1 34  ? 12.31973 36.94036  -5.96360  1.000 18.91561 ? 34  GLU A CB  1 
ATOM   274  C  CG  . GLU A  1 34  ? 11.18218 37.10753  -6.95865  1.000 25.30952 ? 34  GLU A CG  1 
ATOM   275  C  CD  . GLU A  1 34  ? 9.83466  36.74543  -6.36629  1.000 29.67741 ? 34  GLU A CD  1 
ATOM   276  O  OE1 . GLU A  1 34  ? 9.61828  37.02146  -5.16792  1.000 36.42539 ? 34  GLU A OE1 1 
ATOM   277  O  OE2 . GLU A  1 34  ? 8.99361  36.18106  -7.09544  1.000 33.68856 ? 34  GLU A OE2 1 
ATOM   278  N  N   . PHE A  1 35  ? 13.34446 39.48424  -7.81112  1.000 22.70826 ? 35  PHE A N   1 
ATOM   279  C  CA  . PHE A  1 35  ? 13.35519 40.91058  -8.10706  1.000 24.94300 ? 35  PHE A CA  1 
ATOM   280  C  C   . PHE A  1 35  ? 12.70551 41.13097  -9.46629  1.000 25.66967 ? 35  PHE A C   1 
ATOM   281  O  O   . PHE A  1 35  ? 12.35055 40.18201  -10.17061 1.000 23.36330 ? 35  PHE A O   1 
ATOM   282  C  CB  . PHE A  1 35  ? 14.78278 41.46330  -8.08205  1.000 20.79105 ? 35  PHE A CB  1 
ATOM   283  C  CG  . PHE A  1 35  ? 15.69348 40.82186  -9.08978  1.000 24.42766 ? 35  PHE A CG  1 
ATOM   284  C  CD1 . PHE A  1 35  ? 16.32263 39.62131  -8.80859  1.000 24.24200 ? 35  PHE A CD1 1 
ATOM   285  C  CD2 . PHE A  1 35  ? 15.91508 41.41491  -10.32097 1.000 25.25751 ? 35  PHE A CD2 1 
ATOM   286  C  CE1 . PHE A  1 35  ? 17.15501 39.02623  -9.73454  1.000 22.28256 ? 35  PHE A CE1 1 
ATOM   287  C  CE2 . PHE A  1 35  ? 16.74850 40.82415  -11.24982 1.000 22.08107 ? 35  PHE A CE2 1 
ATOM   288  C  CZ  . PHE A  1 35  ? 17.36812 39.62842  -10.95587 1.000 20.19566 ? 35  PHE A CZ  1 
ATOM   289  N  N   . GLN A  1 36  ? 12.55385 42.40048  -9.82921  1.000 31.17228 ? 36  GLN A N   1 
ATOM   290  C  CA  . GLN A  1 36  ? 12.11169 42.79568  -11.15627 1.000 27.22988 ? 36  GLN A CA  1 
ATOM   291  C  C   . GLN A  1 36  ? 13.24362 43.50845  -11.88405 1.000 22.61614 ? 36  GLN A C   1 
ATOM   292  O  O   . GLN A  1 36  ? 14.05121 44.21468  -11.27349 1.000 21.76155 ? 36  GLN A O   1 
ATOM   293  C  CB  . GLN A  1 36  ? 10.88138 43.70675  -11.09317 1.000 27.68996 ? 36  GLN A CB  1 
ATOM   294  C  CG  . GLN A  1 36  ? 9.55473  42.97049  -10.97735 1.000 30.77093 ? 36  GLN A CG  1 
ATOM   295  C  CD  . GLN A  1 36  ? 9.18816  42.64207  -9.54496  1.000 43.21334 ? 36  GLN A CD  1 
ATOM   296  O  OE1 . GLN A  1 36  ? 9.68055  43.26936  -8.60703  1.000 52.58969 ? 36  GLN A OE1 1 
ATOM   297  N  NE2 . GLN A  1 36  ? 8.31656  41.65443  -9.36802  1.000 38.35671 ? 36  GLN A NE2 1 
ATOM   298  N  N   . GLN A  1 37  ? 13.29821 43.31006  -13.19833 1.000 22.55940 ? 37  GLN A N   1 
ATOM   299  C  CA  . GLN A  1 37  ? 14.31242 43.94316  -14.03039 1.000 24.77813 ? 37  GLN A CA  1 
ATOM   300  C  C   . GLN A  1 37  ? 13.73529 44.14965  -15.42119 1.000 22.32552 ? 37  GLN A C   1 
ATOM   301  O  O   . GLN A  1 37  ? 13.12786 43.23403  -15.98335 1.000 21.62561 ? 37  GLN A O   1 
ATOM   302  C  CB  . GLN A  1 37  ? 15.58839 43.09472  -14.09448 1.000 26.01050 ? 37  GLN A CB  1 
ATOM   303  C  CG  . GLN A  1 37  ? 16.68540 43.67660  -14.97255 1.000 22.58278 ? 37  GLN A CG  1 
ATOM   304  C  CD  . GLN A  1 37  ? 17.95345 42.84238  -14.95018 1.000 23.70509 ? 37  GLN A CD  1 
ATOM   305  O  OE1 . GLN A  1 37  ? 18.44803 42.47092  -13.88611 1.000 20.70185 ? 37  GLN A OE1 1 
ATOM   306  N  NE2 . GLN A  1 37  ? 18.48181 42.53757  -16.12939 1.000 27.29292 ? 37  GLN A NE2 1 
ATOM   307  N  N   . GLN A  1 38  ? 13.91656 45.34970  -15.96497 1.000 24.97438 ? 38  GLN A N   1 
ATOM   308  C  CA  . GLN A  1 38  ? 13.38563 45.67560  -17.28172 1.000 22.91562 ? 38  GLN A CA  1 
ATOM   309  C  C   . GLN A  1 38  ? 14.28719 45.07493  -18.35262 1.000 25.78773 ? 38  GLN A C   1 
ATOM   310  O  O   . GLN A  1 38  ? 15.47807 45.39963  -18.42286 1.000 25.41650 ? 38  GLN A O   1 
ATOM   311  C  CB  . GLN A  1 38  ? 13.27475 47.18767  -17.45272 1.000 20.94604 ? 38  GLN A CB  1 
ATOM   312  C  CG  . GLN A  1 38  ? 12.45848 47.60572  -18.66016 1.000 23.33520 ? 38  GLN A CG  1 
ATOM   313  C  CD  . GLN A  1 38  ? 12.46808 49.10231  -18.88334 1.000 23.13398 ? 38  GLN A CD  1 
ATOM   314  O  OE1 . GLN A  1 38  ? 13.42414 49.78951  -18.52394 1.000 35.73300 ? 38  GLN A OE1 1 
ATOM   315  N  NE2 . GLN A  1 38  ? 11.39940 49.61745  -19.47782 1.000 22.51385 ? 38  GLN A NE2 1 
ATOM   316  N  N   . LEU A  1 39  ? 13.72314 44.20054  -19.18620 1.000 20.49244 ? 39  LEU A N   1 
ATOM   317  C  CA  . LEU A  1 39  ? 14.50308 43.50891  -20.20322 1.000 25.78792 ? 39  LEU A CA  1 
ATOM   318  C  C   . LEU A  1 39  ? 14.38058 44.12950  -21.58764 1.000 22.38652 ? 39  LEU A C   1 
ATOM   319  O  O   . LEU A  1 39  ? 15.18740 43.80547  -22.46572 1.000 23.29808 ? 39  LEU A O   1 
ATOM   320  C  CB  . LEU A  1 39  ? 14.09334 42.03230  -20.26966 1.000 24.78064 ? 39  LEU A CB  1 
ATOM   321  C  CG  . LEU A  1 39  ? 14.18319 41.28993  -18.93388 1.000 21.26323 ? 39  LEU A CG  1 
ATOM   322  C  CD1 . LEU A  1 39  ? 13.88004 39.81034  -19.10539 1.000 20.80713 ? 39  LEU A CD1 1 
ATOM   323  C  CD2 . LEU A  1 39  ? 15.55011 41.49396  -18.29749 1.000 23.95232 ? 39  LEU A CD2 1 
ATOM   324  N  N   . HIS A  1 40  ? 13.39901 45.00072  -21.80649 1.000 24.31468 ? 40  HIS A N   1 
ATOM   325  C  CA  . HIS A  1 40  ? 13.26935 45.71989  -23.06427 1.000 26.98448 ? 40  HIS A CA  1 
ATOM   326  C  C   . HIS A  1 40  ? 12.73905 47.11683  -22.78319 1.000 27.58434 ? 40  HIS A C   1 
ATOM   327  O  O   . HIS A  1 40  ? 12.05858 47.34736  -21.78028 1.000 26.90384 ? 40  HIS A O   1 
ATOM   328  C  CB  . HIS A  1 40  ? 12.34527 44.99553  -24.05362 1.000 23.87261 ? 40  HIS A CB  1 
ATOM   329  C  CG  . HIS A  1 40  ? 12.35659 45.58624  -25.42953 1.000 27.19883 ? 40  HIS A CG  1 
ATOM   330  N  ND1 . HIS A  1 40  ? 11.33118 46.37028  -25.91275 1.000 29.61656 ? 40  HIS A ND1 1 
ATOM   331  C  CD2 . HIS A  1 40  ? 13.27627 45.51797  -26.42088 1.000 22.69776 ? 40  HIS A CD2 1 
ATOM   332  C  CE1 . HIS A  1 40  ? 11.61481 46.75261  -27.14508 1.000 24.29360 ? 40  HIS A CE1 1 
ATOM   333  N  NE2 . HIS A  1 40  ? 12.78924 46.24845  -27.47748 1.000 24.84777 ? 40  HIS A NE2 1 
ATOM   334  N  N   . ARG A  1 41  ? 13.05851 48.04703  -23.68828 1.000 26.20702 ? 41  ARG A N   1 
ATOM   335  C  CA  . ARG A  1 41  ? 12.66571 49.44146  -23.50607 1.000 30.27093 ? 41  ARG A CA  1 
ATOM   336  C  C   . ARG A  1 41  ? 11.15737 49.59534  -23.35373 1.000 25.85420 ? 41  ARG A C   1 
ATOM   337  O  O   . ARG A  1 41  ? 10.69570 50.48100  -22.62429 1.000 21.57925 ? 41  ARG A O   1 
ATOM   338  C  CB  . ARG A  1 41  ? 13.16417 50.27896  -24.68456 1.000 28.06083 ? 41  ARG A CB  1 
ATOM   339  C  CG  . ARG A  1 41  ? 12.84873 51.76165  -24.58266 1.000 22.42683 ? 41  ARG A CG  1 
ATOM   340  C  CD  . ARG A  1 41  ? 12.87180 52.41246  -25.95276 1.000 17.33029 ? 41  ARG A CD  1 
ATOM   341  N  NE  . ARG A  1 41  ? 11.86685 51.82967  -26.83309 1.000 22.82566 ? 41  ARG A NE  1 
ATOM   342  C  CZ  . ARG A  1 41  ? 11.76655 52.08584  -28.12984 1.000 26.96634 ? 41  ARG A CZ  1 
ATOM   343  N  NH1 . ARG A  1 41  ? 12.60384 52.91060  -28.73826 1.000 23.72776 ? 41  ARG A NH1 1 
ATOM   344  N  NH2 . ARG A  1 41  ? 10.80427 51.49696  -28.83451 1.000 23.89895 ? 41  ARG A NH2 1 
ATOM   345  N  N   . ASP A  1 42  ? 10.37690 48.74602  -24.02167 1.000 23.21110 ? 42  ASP A N   1 
ATOM   346  C  CA  . ASP A  1 42  ? 8.92297  48.83890  -24.00447 1.000 25.53942 ? 42  ASP A CA  1 
ATOM   347  C  C   . ASP A  1 42  ? 8.27060  47.72874  -23.19011 1.000 28.89305 ? 42  ASP A C   1 
ATOM   348  O  O   . ASP A  1 42  ? 7.05634  47.52859  -23.29542 1.000 33.03274 ? 42  ASP A O   1 
ATOM   349  C  CB  . ASP A  1 42  ? 8.37905  48.82756  -25.43430 1.000 23.69834 ? 42  ASP A CB  1 
ATOM   350  C  CG  . ASP A  1 42  ? 9.09241  49.81533  -26.33557 1.000 23.82677 ? 42  ASP A CG  1 
ATOM   351  O  OD1 . ASP A  1 42  ? 9.47071  50.90213  -25.84928 1.000 26.76858 ? 42  ASP A OD1 1 
ATOM   352  O  OD2 . ASP A  1 42  ? 9.28172  49.50081  -27.52947 1.000 21.62161 ? 42  ASP A OD2 1 
ATOM   353  N  N   . LEU A  1 43  ? 9.04188  46.99975  -22.38846 1.000 28.25256 ? 43  LEU A N   1 
ATOM   354  C  CA  . LEU A  1 43  ? 8.41091  45.97598  -21.56739 1.000 26.77209 ? 43  LEU A CA  1 
ATOM   355  C  C   . LEU A  1 43  ? 8.33669  46.42086  -20.11378 1.000 30.36996 ? 43  LEU A C   1 
ATOM   356  O  O   . LEU A  1 43  ? 9.25474  47.08633  -19.61953 1.000 25.68722 ? 43  LEU A O   1 
ATOM   357  C  CB  . LEU A  1 43  ? 9.18341  44.65773  -21.64123 1.000 25.02385 ? 43  LEU A CB  1 
ATOM   358  C  CG  . LEU A  1 43  ? 8.83803  43.66958  -22.75526 1.000 30.33641 ? 43  LEU A CG  1 
ATOM   359  C  CD1 . LEU A  1 43  ? 9.72744  42.43949  -22.65925 1.000 31.48713 ? 43  LEU A CD1 1 
ATOM   360  C  CD2 . LEU A  1 43  ? 7.37110  43.27572  -22.69005 1.000 26.71562 ? 43  LEU A CD2 1 
ATOM   361  N  N   . PRO A  1 44  ? 7.26073  46.07685  -19.41274 1.000 26.71608 ? 44  PRO A N   1 
ATOM   362  C  CA  . PRO A  1 44  ? 7.23180  46.26251  -17.96081 1.000 25.08665 ? 44  PRO A CA  1 
ATOM   363  C  C   . PRO A  1 44  ? 8.27212  45.37578  -17.30257 1.000 27.40302 ? 44  PRO A C   1 
ATOM   364  O  O   . PRO A  1 44  ? 8.72209  44.39095  -17.90702 1.000 31.19877 ? 44  PRO A O   1 
ATOM   365  C  CB  . PRO A  1 44  ? 5.80480  45.83860  -17.57496 1.000 28.43553 ? 44  PRO A CB  1 
ATOM   366  C  CG  . PRO A  1 44  ? 5.01928  45.91819  -18.84499 1.000 26.29373 ? 44  PRO A CG  1 
ATOM   367  C  CD  . PRO A  1 44  ? 5.98302  45.56192  -19.93133 1.000 25.67832 ? 44  PRO A CD  1 
ATOM   368  N  N   . PRO A  1 45  ? 8.69054  45.69115  -16.07728 1.000 30.30560 ? 45  PRO A N   1 
ATOM   369  C  CA  . PRO A  1 45  ? 9.73021  44.88247  -15.42566 1.000 27.49466 ? 45  PRO A CA  1 
ATOM   370  C  C   . PRO A  1 45  ? 9.32511  43.41872  -15.31889 1.000 25.67799 ? 45  PRO A C   1 
ATOM   371  O  O   . PRO A  1 45  ? 8.14123  43.07790  -15.26378 1.000 26.40063 ? 45  PRO A O   1 
ATOM   372  C  CB  . PRO A  1 45  ? 9.87012  45.52957  -14.04255 1.000 25.77653 ? 45  PRO A CB  1 
ATOM   373  C  CG  . PRO A  1 45  ? 9.40471  46.93392  -14.24420 1.000 27.16755 ? 45  PRO A CG  1 
ATOM   374  C  CD  . PRO A  1 45  ? 8.29878  46.85364  -15.26395 1.000 23.81591 ? 45  PRO A CD  1 
ATOM   375  N  N   . THR A  1 46  ? 10.33094 42.54889  -15.30520 1.000 25.76769 ? 46  THR A N   1 
ATOM   376  C  CA  . THR A  1 46  ? 10.13082 41.10590  -15.35391 1.000 23.21358 ? 46  THR A CA  1 
ATOM   377  C  C   . THR A  1 46  ? 10.53674 40.48992  -14.02146 1.000 27.03283 ? 46  THR A C   1 
ATOM   378  O  O   . THR A  1 46  ? 11.67861 40.65755  -13.57792 1.000 22.47305 ? 46  THR A O   1 
ATOM   379  C  CB  . THR A  1 46  ? 10.93669 40.48232  -16.49399 1.000 23.74298 ? 46  THR A CB  1 
ATOM   380  O  OG1 . THR A  1 46  ? 10.63282 41.15497  -17.72252 1.000 22.07352 ? 46  THR A OG1 1 
ATOM   381  C  CG2 . THR A  1 46  ? 10.60058 39.00558  -16.63526 1.000 22.66678 ? 46  THR A CG2 1 
ATOM   382  N  N   . ARG A  1 47  ? 9.60459  39.77664  -13.39299 1.000 20.37924 ? 47  ARG A N   1 
ATOM   383  C  CA  . ARG A  1 47  ? 9.91219  39.04480  -12.17181 1.000 23.85504 ? 47  ARG A CA  1 
ATOM   384  C  C   . ARG A  1 47  ? 10.88608 37.91283  -12.47955 1.000 22.54972 ? 47  ARG A C   1 
ATOM   385  O  O   . ARG A  1 47  ? 10.62972 37.07896  -13.35352 1.000 24.32013 ? 47  ARG A O   1 
ATOM   386  C  CB  . ARG A  1 47  ? 8.62790  38.49897  -11.54821 1.000 26.93346 ? 47  ARG A CB  1 
ATOM   387  C  CG  . ARG A  1 47  ? 8.84408  37.59360  -10.34798 1.000 28.03587 ? 47  ARG A CG  1 
ATOM   388  C  CD  . ARG A  1 47  ? 7.51944  37.16238  -9.72969  1.000 34.42947 ? 47  ARG A CD  1 
ATOM   389  N  NE  . ARG A  1 47  ? 6.87591  38.24153  -8.98841  1.000 41.07410 ? 47  ARG A NE  1 
ATOM   390  C  CZ  . ARG A  1 47  ? 5.86453  38.96881  -9.44381  1.000 44.03974 ? 47  ARG A CZ  1 
ATOM   391  N  NH1 . ARG A  1 47  ? 5.34304  38.75545  -10.64102 1.000 42.49860 ? 47  ARG A NH1 1 
ATOM   392  N  NH2 . ARG A  1 47  ? 5.36120  39.93237  -8.67700  1.000 39.25449 ? 47  ARG A NH2 1 
ATOM   393  N  N   . LEU A  1 48  ? 12.00876 37.88546  -11.76388 1.000 22.04399 ? 48  LEU A N   1 
ATOM   394  C  CA  . LEU A  1 48  ? 13.09332 36.96527  -12.07152 1.000 20.33384 ? 48  LEU A CA  1 
ATOM   395  C  C   . LEU A  1 48  ? 13.69856 36.40905  -10.79140 1.000 18.41990 ? 48  LEU A C   1 
ATOM   396  O  O   . LEU A  1 48  ? 13.64942 37.04133  -9.73282  1.000 19.90274 ? 48  LEU A O   1 
ATOM   397  C  CB  . LEU A  1 48  ? 14.19722 37.65388  -12.88882 1.000 15.74934 ? 48  LEU A CB  1 
ATOM   398  C  CG  . LEU A  1 48  ? 13.84251 38.21902  -14.26426 1.000 20.47312 ? 48  LEU A CG  1 
ATOM   399  C  CD1 . LEU A  1 48  ? 14.81629 39.32224  -14.64562 1.000 20.32023 ? 48  LEU A CD1 1 
ATOM   400  C  CD2 . LEU A  1 48  ? 13.84997 37.11737  -15.31126 1.000 21.32781 ? 48  LEU A CD2 1 
ATOM   401  N  N   . PHE A  1 49  ? 14.26622 35.21137  -10.90389 1.000 17.92176 ? 49  PHE A N   1 
ATOM   402  C  CA  . PHE A  1 49  ? 15.18118 34.67025  -9.90782  1.000 19.51333 ? 49  PHE A CA  1 
ATOM   403  C  C   . PHE A  1 49  ? 16.60062 34.90521  -10.40379 1.000 15.93827 ? 49  PHE A C   1 
ATOM   404  O  O   . PHE A  1 49  ? 16.93474 34.52600  -11.53019 1.000 18.79099 ? 49  PHE A O   1 
ATOM   405  C  CB  . PHE A  1 49  ? 14.94552 33.17566  -9.67740  1.000 15.21215 ? 49  PHE A CB  1 
ATOM   406  C  CG  . PHE A  1 49  ? 13.65807 32.85789  -8.97109  1.000 17.73079 ? 49  PHE A CG  1 
ATOM   407  C  CD1 . PHE A  1 49  ? 12.92622 33.85155  -8.34215  1.000 20.25659 ? 49  PHE A CD1 1 
ATOM   408  C  CD2 . PHE A  1 49  ? 13.18622 31.55578  -8.92703  1.000 18.93498 ? 49  PHE A CD2 1 
ATOM   409  C  CE1 . PHE A  1 49  ? 11.74304 33.55276  -7.68899  1.000 21.85391 ? 49  PHE A CE1 1 
ATOM   410  C  CE2 . PHE A  1 49  ? 12.00533 31.25068  -8.27597  1.000 21.46625 ? 49  PHE A CE2 1 
ATOM   411  C  CZ  . PHE A  1 49  ? 11.28286 32.25068  -7.65598  1.000 19.99911 ? 49  PHE A CZ  1 
ATOM   412  N  N   . GLY A  1 50  ? 17.42976 35.53422  -9.57723  1.000 16.42976 ? 50  GLY A N   1 
ATOM   413  C  CA  . GLY A  1 50  ? 18.75067 35.92150  -10.03349 1.000 17.36784 ? 50  GLY A CA  1 
ATOM   414  C  C   . GLY A  1 50  ? 19.78082 35.94392  -8.92691  1.000 19.81119 ? 50  GLY A C   1 
ATOM   415  O  O   . GLY A  1 50  ? 19.45883 36.06462  -7.73969  1.000 19.44030 ? 50  GLY A O   1 
ATOM   416  N  N   . TYR A  1 51  ? 21.03958 35.82715  -9.34361  1.000 17.75255 ? 51  TYR A N   1 
ATOM   417  C  CA  . TYR A  1 51  ? 22.16666 35.93033  -8.42920  1.000 20.07041 ? 51  TYR A CA  1 
ATOM   418  C  C   . TYR A  1 51  ? 22.47382 37.39638  -8.15324  1.000 20.89563 ? 51  TYR A C   1 
ATOM   419  O  O   . TYR A  1 51  ? 22.62880 38.19130  -9.08632  1.000 20.80335 ? 51  TYR A O   1 
ATOM   420  C  CB  . TYR A  1 51  ? 23.39599 35.23685  -9.01534  1.000 20.63804 ? 51  TYR A CB  1 
ATOM   421  C  CG  . TYR A  1 51  ? 23.21545 33.75848  -9.27949  1.000 18.04052 ? 51  TYR A CG  1 
ATOM   422  C  CD1 . TYR A  1 51  ? 23.22749 32.84036  -8.23772  1.000 18.76302 ? 51  TYR A CD1 1 
ATOM   423  C  CD2 . TYR A  1 51  ? 23.04486 33.28037  -10.57159 1.000 15.98027 ? 51  TYR A CD2 1 
ATOM   424  C  CE1 . TYR A  1 51  ? 23.06904 31.48987  -8.47477  1.000 17.69180 ? 51  TYR A CE1 1 
ATOM   425  C  CE2 . TYR A  1 51  ? 22.88747 31.93113  -10.81807 1.000 14.95600 ? 51  TYR A CE2 1 
ATOM   426  C  CZ  . TYR A  1 51  ? 22.89935 31.04062  -9.76699  1.000 16.63723 ? 51  TYR A CZ  1 
ATOM   427  O  OH  . TYR A  1 51  ? 22.74046 29.69488  -10.00786 1.000 20.36381 ? 51  TYR A OH  1 
ATOM   428  N  N   . ASN A  1 52  ? 22.56070 37.74831  -6.86873  1.000 23.70402 ? 52  ASN A N   1 
ATOM   429  C  CA  . ASN A  1 52  ? 22.83668 39.12029  -6.43677  1.000 15.37795 ? 52  ASN A CA  1 
ATOM   430  C  C   . ASN A  1 52  ? 21.85826 40.10961  -7.06553  1.000 15.40339 ? 52  ASN A C   1 
ATOM   431  O  O   . ASN A  1 52  ? 22.22034 41.22982  -7.43034  1.000 19.67324 ? 52  ASN A O   1 
ATOM   432  C  CB  . ASN A  1 52  ? 24.28449 39.51273  -6.73706  1.000 13.75940 ? 52  ASN A CB  1 
ATOM   433  C  CG  . ASN A  1 52  ? 25.26652 38.92066  -5.74357  1.000 13.20282 ? 52  ASN A CG  1 
ATOM   434  O  OD1 . ASN A  1 52  ? 24.92202 38.02821  -4.97012  1.000 18.26347 ? 52  ASN A OD1 1 
ATOM   435  N  ND2 . ASN A  1 52  ? 26.49757 39.41779  -5.75914  1.000 11.28177 ? 52  ASN A ND2 1 
ATOM   436  N  N   . GLY A  1 53  ? 20.60606 39.68294  -7.19837  1.000 19.17477 ? 53  GLY A N   1 
ATOM   437  C  CA  . GLY A  1 53  ? 19.54736 40.55897  -7.67703  1.000 15.78672 ? 53  GLY A CA  1 
ATOM   438  C  C   . GLY A  1 53  ? 19.79297 41.16964  -9.03923  1.000 19.86238 ? 53  GLY A C   1 
ATOM   439  O  O   . GLY A  1 53  ? 19.44532 42.33571  -9.26384  1.000 21.69252 ? 53  GLY A O   1 
ATOM   440  N  N   . VAL A  1 54  ? 20.38267 40.40990  -9.96098  1.000 20.61051 ? 54  VAL A N   1 
ATOM   441  C  CA  . VAL A  1 54  ? 20.69008 40.92842  -11.28736 1.000 19.35851 ? 54  VAL A CA  1 
ATOM   442  C  C   . VAL A  1 54  ? 20.64598 39.77755  -12.28383 1.000 20.18932 ? 54  VAL A C   1 
ATOM   443  O  O   . VAL A  1 54  ? 20.93288 38.62631  -11.94476 1.000 21.30642 ? 54  VAL A O   1 
ATOM   444  C  CB  . VAL A  1 54  ? 22.05616 41.65890  -11.30088 1.000 17.83545 ? 54  VAL A CB  1 
ATOM   445  C  CG1 . VAL A  1 54  ? 23.21097 40.67047  -11.36515 1.000 25.28186 ? 54  VAL A CG1 1 
ATOM   446  C  CG2 . VAL A  1 54  ? 22.11820 42.64504  -12.44684 1.000 24.29977 ? 54  VAL A CG2 1 
ATOM   447  N  N   . TYR A  1 55  ? 20.25508 40.09288  -13.51817 1.000 21.54450 ? 55  TYR A N   1 
ATOM   448  C  CA  . TYR A  1 55  ? 20.12424 39.09826  -14.58020 1.000 20.90544 ? 55  TYR A CA  1 
ATOM   449  C  C   . TYR A  1 55  ? 20.84342 39.60310  -15.82364 1.000 21.46961 ? 55  TYR A C   1 
ATOM   450  O  O   . TYR A  1 55  ? 20.45730 40.65408  -16.37620 1.000 23.61487 ? 55  TYR A O   1 
ATOM   451  C  CB  . TYR A  1 55  ? 18.65382 38.80092  -14.88278 1.000 19.13571 ? 55  TYR A CB  1 
ATOM   452  C  CG  . TYR A  1 55  ? 18.43237 38.00067  -16.14949 1.000 19.89902 ? 55  TYR A CG  1 
ATOM   453  C  CD1 . TYR A  1 55  ? 18.97008 36.72797  -16.29577 1.000 21.69523 ? 55  TYR A CD1 1 
ATOM   454  C  CD2 . TYR A  1 55  ? 17.67320 38.51386  -17.19372 1.000 22.99223 ? 55  TYR A CD2 1 
ATOM   455  C  CE1 . TYR A  1 55  ? 18.76546 35.99198  -17.45133 1.000 20.83619 ? 55  TYR A CE1 1 
ATOM   456  C  CE2 . TYR A  1 55  ? 17.46295 37.78624  -18.35180 1.000 23.11638 ? 55  TYR A CE2 1 
ATOM   457  C  CZ  . TYR A  1 55  ? 18.01038 36.52646  -18.47520 1.000 20.95595 ? 55  TYR A CZ  1 
ATOM   458  O  OH  . TYR A  1 55  ? 17.80075 35.80093  -19.62559 1.000 17.58646 ? 55  TYR A OH  1 
ATOM   459  N  N   . PRO A  1 56  ? 21.88367 38.90795  -16.30194 1.000 18.93721 ? 56  PRO A N   1 
ATOM   460  C  CA  . PRO A  1 56  ? 22.47829 37.68663  -15.73665 1.000 17.58996 ? 56  PRO A CA  1 
ATOM   461  C  C   . PRO A  1 56  ? 23.24988 37.98989  -14.45934 1.000 21.70071 ? 56  PRO A C   1 
ATOM   462  O  O   . PRO A  1 56  ? 23.46105 39.15381  -14.13083 1.000 20.98586 ? 56  PRO A O   1 
ATOM   463  C  CB  . PRO A  1 56  ? 23.39235 37.19413  -16.86725 1.000 17.20808 ? 56  PRO A CB  1 
ATOM   464  C  CG  . PRO A  1 56  ? 23.79021 38.44671  -17.58894 1.000 21.04885 ? 56  PRO A CG  1 
ATOM   465  C  CD  . PRO A  1 56  ? 22.56717 39.32803  -17.53848 1.000 23.60751 ? 56  PRO A CD  1 
ATOM   466  N  N   . GLY A  1 57  ? 23.67782 36.97037  -13.71987 1.000 16.02327 ? 57  GLY A N   1 
ATOM   467  C  CA  . GLY A  1 57  ? 24.37892 37.17653  -12.47638 1.000 17.34589 ? 57  GLY A CA  1 
ATOM   468  C  C   . GLY A  1 57  ? 25.72187 37.84901  -12.67095 1.000 17.90064 ? 57  GLY A C   1 
ATOM   469  O  O   . GLY A  1 57  ? 26.17883 38.06413  -13.79817 1.000 14.92125 ? 57  GLY A O   1 
ATOM   470  N  N   . PRO A  1 58  ? 26.37745 38.20503  -11.56699 1.000 20.22088 ? 58  PRO A N   1 
ATOM   471  C  CA  . PRO A  1 58  ? 27.71208 38.80602  -11.66627 1.000 18.30523 ? 58  PRO A CA  1 
ATOM   472  C  C   . PRO A  1 58  ? 28.69349 37.85887  -12.33976 1.000 18.17009 ? 58  PRO A C   1 
ATOM   473  O  O   . PRO A  1 58  ? 28.53312 36.63646  -12.31106 1.000 21.94027 ? 58  PRO A O   1 
ATOM   474  C  CB  . PRO A  1 58  ? 28.09697 39.06287  -10.20448 1.000 14.40863 ? 58  PRO A CB  1 
ATOM   475  C  CG  . PRO A  1 58  ? 26.80017 39.09910  -9.46643  1.000 14.13380 ? 58  PRO A CG  1 
ATOM   476  C  CD  . PRO A  1 58  ? 25.90159 38.13390  -10.17608 1.000 14.91342 ? 58  PRO A CD  1 
ATOM   477  N  N   . THR A  1 59  ? 29.71927 38.43984  -12.95198 1.000 15.97139 ? 59  THR A N   1 
ATOM   478  C  CA  . THR A  1 59  ? 30.72382 37.68271  -13.68531 1.000 17.01538 ? 59  THR A CA  1 
ATOM   479  C  C   . THR A  1 59  ? 31.93559 37.43406  -12.79734 1.000 18.80801 ? 59  THR A C   1 
ATOM   480  O  O   . THR A  1 59  ? 32.51411 38.37815  -12.24923 1.000 21.61757 ? 59  THR A O   1 
ATOM   481  C  CB  . THR A  1 59  ? 31.14284 38.42298  -14.95652 1.000 18.11905 ? 59  THR A CB  1 
ATOM   482  O  OG1 . THR A  1 59  ? 30.04491 38.44744  -15.87753 1.000 17.29446 ? 59  THR A OG1 1 
ATOM   483  C  CG2 . THR A  1 59  ? 32.33489 37.73522  -15.60737 1.000 12.83762 ? 59  THR A CG2 1 
ATOM   484  N  N   . PHE A  1 60  ? 32.30900 36.16559  -12.65425 1.000 18.72707 ? 60  PHE A N   1 
ATOM   485  C  CA  . PHE A  1 60  ? 33.50755 35.80195  -11.91308 1.000 14.95446 ? 60  PHE A CA  1 
ATOM   486  C  C   . PHE A  1 60  ? 34.74212 35.94546  -12.79186 1.000 17.00527 ? 60  PHE A C   1 
ATOM   487  O  O   . PHE A  1 60  ? 34.74287 35.54158  -13.95791 1.000 19.67845 ? 60  PHE A O   1 
ATOM   488  C  CB  . PHE A  1 60  ? 33.41720 34.36216  -11.41001 1.000 11.61267 ? 60  PHE A CB  1 
ATOM   489  C  CG  . PHE A  1 60  ? 32.55038 34.18350  -10.19699 1.000 13.72297 ? 60  PHE A CG  1 
ATOM   490  C  CD1 . PHE A  1 60  ? 31.17095 34.15303  -10.30919 1.000 12.42651 ? 60  PHE A CD1 1 
ATOM   491  C  CD2 . PHE A  1 60  ? 33.11978 34.01092  -8.94573  1.000 14.50940 ? 60  PHE A CD2 1 
ATOM   492  C  CE1 . PHE A  1 60  ? 30.37548 33.97578  -9.19258  1.000 16.41370 ? 60  PHE A CE1 1 
ATOM   493  C  CE2 . PHE A  1 60  ? 32.32933 33.83039  -7.82585  1.000 13.03251 ? 60  PHE A CE2 1 
ATOM   494  C  CZ  . PHE A  1 60  ? 30.95623 33.81231  -7.94963  1.000 12.80665 ? 60  PHE A CZ  1 
ATOM   495  N  N   . GLU A  1 61  ? 35.79920 36.51698  -12.22207 1.000 20.09433 ? 61  GLU A N   1 
ATOM   496  C  CA  . GLU A  1 61  ? 37.11277 36.56992  -12.85555 1.000 15.83796 ? 61  GLU A CA  1 
ATOM   497  C  C   . GLU A  1 61  ? 38.10485 35.90331  -11.91377 1.000 17.92446 ? 61  GLU A C   1 
ATOM   498  O  O   . GLU A  1 61  ? 38.46687 36.47504  -10.87939 1.000 21.69198 ? 61  GLU A O   1 
ATOM   499  C  CB  . GLU A  1 61  ? 37.52579 38.00742  -13.16893 1.000 14.24291 ? 61  GLU A CB  1 
ATOM   500  C  CG  . GLU A  1 61  ? 36.81567 38.61560  -14.36838 1.000 21.10533 ? 61  GLU A CG  1 
ATOM   501  C  CD  . GLU A  1 61  ? 37.33100 38.08237  -15.69512 1.000 21.36431 ? 61  GLU A CD  1 
ATOM   502  O  OE1 . GLU A  1 61  ? 38.34579 37.35300  -15.69897 1.000 20.61242 ? 61  GLU A OE1 1 
ATOM   503  O  OE2 . GLU A  1 61  ? 36.72175 38.39952  -16.73815 1.000 23.54988 ? 61  GLU A OE2 1 
ATOM   504  N  N   . VAL A  1 62  ? 38.53290 34.69298  -12.26480 1.000 18.77110 ? 62  VAL A N   1 
ATOM   505  C  CA  . VAL A  1 62  ? 39.44909 33.91562  -11.44516 1.000 17.94709 ? 62  VAL A CA  1 
ATOM   506  C  C   . VAL A  1 62  ? 40.68541 33.58481  -12.27490 1.000 18.28484 ? 62  VAL A C   1 
ATOM   507  O  O   . VAL A  1 62  ? 40.70462 33.74006  -13.49583 1.000 18.47295 ? 62  VAL A O   1 
ATOM   508  C  CB  . VAL A  1 62  ? 38.79788 32.63017  -10.89562 1.000 20.14016 ? 62  VAL A CB  1 
ATOM   509  C  CG1 . VAL A  1 62  ? 37.44716 32.94060  -10.26658 1.000 13.04670 ? 62  VAL A CG1 1 
ATOM   510  C  CG2 . VAL A  1 62  ? 38.65412 31.59203  -11.99516 1.000 14.99797 ? 62  VAL A CG2 1 
ATOM   511  N  N   . GLN A  1 63  ? 41.72619 33.12692  -11.58656 1.000 20.97944 ? 63  GLN A N   1 
ATOM   512  C  CA  . GLN A  1 63  ? 42.97609 32.71990  -12.20825 1.000 18.46343 ? 63  GLN A CA  1 
ATOM   513  C  C   . GLN A  1 63  ? 43.18190 31.22174  -12.03240 1.000 24.07124 ? 63  GLN A C   1 
ATOM   514  O  O   . GLN A  1 63  ? 42.58912 30.58944  -11.15421 1.000 20.99244 ? 63  GLN A O   1 
ATOM   515  C  CB  . GLN A  1 63  ? 44.16992 33.46588  -11.60111 1.000 18.73047 ? 63  GLN A CB  1 
ATOM   516  C  CG  . GLN A  1 63  ? 43.98304 34.96186  -11.46341 1.000 27.67448 ? 63  GLN A CG  1 
ATOM   517  C  CD  . GLN A  1 63  ? 43.88296 35.66010  -12.80047 1.000 39.54380 ? 63  GLN A CD  1 
ATOM   518  O  OE1 . GLN A  1 63  ? 44.69827 35.43463  -13.69674 1.000 42.13580 ? 63  GLN A OE1 1 
ATOM   519  N  NE2 . GLN A  1 63  ? 42.87538 36.51318  -12.94558 1.000 38.45648 ? 63  GLN A NE2 1 
ATOM   520  N  N   . LYS A  1 64  ? 44.04345 30.65931  -12.87591 1.000 23.80719 ? 64  LYS A N   1 
ATOM   521  C  CA  . LYS A  1 64  ? 44.45513 29.27729  -12.69543 1.000 20.57000 ? 64  LYS A CA  1 
ATOM   522  C  C   . LYS A  1 64  ? 45.18498 29.13379  -11.36806 1.000 21.17937 ? 64  LYS A C   1 
ATOM   523  O  O   . LYS A  1 64  ? 45.97971 30.00033  -10.98694 1.000 23.82357 ? 64  LYS A O   1 
ATOM   524  C  CB  . LYS A  1 64  ? 45.35118 28.83776  -13.85425 1.000 18.24439 ? 64  LYS A CB  1 
ATOM   525  C  CG  . LYS A  1 64  ? 45.75442 27.37360  -13.82034 1.000 20.09048 ? 64  LYS A CG  1 
ATOM   526  C  CD  . LYS A  1 64  ? 46.70948 27.04146  -14.95672 1.000 22.01035 ? 64  LYS A CD  1 
ATOM   527  C  CE  . LYS A  1 64  ? 47.05709 25.56367  -14.99908 1.000 19.10991 ? 64  LYS A CE  1 
ATOM   528  N  NZ  . LYS A  1 64  ? 47.92955 25.25038  -16.16429 1.000 22.55357 ? 64  LYS A NZ  1 
ATOM   529  N  N   . HIS A  1 65  ? 44.88216 28.04419  -10.65146 1.000 24.66156 ? 65  HIS A N   1 
ATOM   530  C  CA  . HIS A  1 65  ? 45.44451 27.70998  -9.34386  1.000 21.90946 ? 65  HIS A CA  1 
ATOM   531  C  C   . HIS A  1 65  ? 44.82972 28.54309  -8.22422  1.000 22.21895 ? 65  HIS A C   1 
ATOM   532  O  O   . HIS A  1 65  ? 45.07396 28.25973  -7.04811  1.000 26.70834 ? 65  HIS A O   1 
ATOM   533  C  CB  . HIS A  1 65  ? 46.97144 27.87732  -9.30997  1.000 18.04386 ? 65  HIS A CB  1 
ATOM   534  C  CG  . HIS A  1 65  ? 47.68183 27.28618  -10.48888 1.000 19.87011 ? 65  HIS A CG  1 
ATOM   535  N  ND1 . HIS A  1 65  ? 47.79319 25.92692  -10.68010 1.000 15.78675 ? 65  HIS A ND1 1 
ATOM   536  C  CD2 . HIS A  1 65  ? 48.32512 27.86679  -11.53083 1.000 20.23717 ? 65  HIS A CD2 1 
ATOM   537  C  CE1 . HIS A  1 65  ? 48.47670 25.69367  -11.78569 1.000 17.67319 ? 65  HIS A CE1 1 
ATOM   538  N  NE2 . HIS A  1 65  ? 48.81148 26.85383  -12.32144 1.000 21.26983 ? 65  HIS A NE2 1 
ATOM   539  N  N   . GLU A  1 66  ? 44.04260 29.56460  -8.55865  1.000 21.70850 ? 66  GLU A N   1 
ATOM   540  C  CA  . GLU A  1 66  ? 43.41621 30.38477  -7.52876  1.000 18.16130 ? 66  GLU A CA  1 
ATOM   541  C  C   . GLU A  1 66  ? 42.32251 29.58659  -6.83039  1.000 19.31690 ? 66  GLU A C   1 
ATOM   542  O  O   . GLU A  1 66  ? 41.34413 29.18031  -7.46477  1.000 21.25652 ? 66  GLU A O   1 
ATOM   543  C  CB  . GLU A  1 66  ? 42.84105 31.66067  -8.13653  1.000 14.70989 ? 66  GLU A CB  1 
ATOM   544  C  CG  . GLU A  1 66  ? 42.14029 32.55592  -7.12731  1.000 14.63088 ? 66  GLU A CG  1 
ATOM   545  C  CD  . GLU A  1 66  ? 41.55717 33.81806  -7.74217  1.000 22.46412 ? 66  GLU A CD  1 
ATOM   546  O  OE1 . GLU A  1 66  ? 41.80886 34.06549  -8.93717  1.000 21.59661 ? 66  GLU A OE1 1 
ATOM   547  O  OE2 . GLU A  1 66  ? 40.84617 34.56355  -7.02970  1.000 20.63704 ? 66  GLU A OE2 1 
ATOM   548  N  N   . LYS A  1 67  ? 42.49623 29.34723  -5.53375  1.000 21.11520 ? 67  LYS A N   1 
ATOM   549  C  CA  . LYS A  1 67  ? 41.50942 28.62331  -4.74195  1.000 21.98914 ? 67  LYS A CA  1 
ATOM   550  C  C   . LYS A  1 67  ? 40.35256 29.56609  -4.43291  1.000 26.04122 ? 67  LYS A C   1 
ATOM   551  O  O   . LYS A  1 67  ? 40.49559 30.49178  -3.62713  1.000 27.37427 ? 67  LYS A O   1 
ATOM   552  C  CB  . LYS A  1 67  ? 42.14773 28.08666  -3.46368  1.000 29.65910 ? 67  LYS A CB  1 
ATOM   553  C  CG  . LYS A  1 67  ? 41.60362 26.73674  -3.00634  1.000 51.23334 ? 67  LYS A CG  1 
ATOM   554  C  CD  . LYS A  1 67  ? 42.13199 26.36557  -1.62336  1.000 57.72204 ? 67  LYS A CD  1 
ATOM   555  C  CE  . LYS A  1 67  ? 41.78383 24.93074  -1.24713  1.000 68.16610 ? 67  LYS A CE  1 
ATOM   556  N  NZ  . LYS A  1 67  ? 42.56584 23.93851  -2.03901  1.000 68.02751 ? 67  LYS A NZ  1 
ATOM   557  N  N   . VAL A  1 68  ? 39.20484 29.33063  -5.06493  1.000 17.51241 ? 68  VAL A N   1 
ATOM   558  C  CA  . VAL A  1 68  ? 38.04351 30.20671  -4.96095  1.000 15.68818 ? 68  VAL A CA  1 
ATOM   559  C  C   . VAL A  1 68  ? 36.97011 29.50746  -4.14038  1.000 18.02947 ? 68  VAL A C   1 
ATOM   560  O  O   . VAL A  1 68  ? 36.64207 28.34257  -4.39620  1.000 21.96269 ? 68  VAL A O   1 
ATOM   561  C  CB  . VAL A  1 68  ? 37.50901 30.59749  -6.34977  1.000 20.91270 ? 68  VAL A CB  1 
ATOM   562  C  CG1 . VAL A  1 68  ? 36.10936 31.18908  -6.24062  1.000 16.44136 ? 68  VAL A CG1 1 
ATOM   563  C  CG2 . VAL A  1 68  ? 38.45139 31.58753  -7.01446  1.000 19.33573 ? 68  VAL A CG2 1 
ATOM   564  N  N   . ALA A  1 69  ? 36.42255 30.22079  -3.15893  1.000 21.02225 ? 69  ALA A N   1 
ATOM   565  C  CA  . ALA A  1 69  ? 35.34615 29.72092  -2.31612  1.000 16.13140 ? 69  ALA A CA  1 
ATOM   566  C  C   . ALA A  1 69  ? 34.11891 30.59934  -2.50041  1.000 18.36330 ? 69  ALA A C   1 
ATOM   567  O  O   . ALA A  1 69  ? 34.20521 31.82587  -2.38080  1.000 20.47521 ? 69  ALA A O   1 
ATOM   568  C  CB  . ALA A  1 69  ? 35.75885 29.69380  -0.84379  1.000 14.90361 ? 69  ALA A CB  1 
ATOM   569  N  N   . VAL A  1 70  ? 32.98183 29.97410  -2.79464  1.000 18.89859 ? 70  VAL A N   1 
ATOM   570  C  CA  . VAL A  1 70  ? 31.72211 30.68200  -2.98284  1.000 18.09988 ? 70  VAL A CA  1 
ATOM   571  C  C   . VAL A  1 70  ? 30.68536 30.07617  -2.05071  1.000 17.92363 ? 70  VAL A C   1 
ATOM   572  O  O   . VAL A  1 70  ? 30.51930 28.85216  -2.01152  1.000 16.37301 ? 70  VAL A O   1 
ATOM   573  C  CB  . VAL A  1 70  ? 31.22736 30.61550  -4.44048  1.000 13.05138 ? 70  VAL A CB  1 
ATOM   574  C  CG1 . VAL A  1 70  ? 30.08993 31.60127  -4.64746  1.000 12.04702 ? 70  VAL A CG1 1 
ATOM   575  C  CG2 . VAL A  1 70  ? 32.36579 30.88461  -5.41197  1.000 13.98416 ? 70  VAL A CG2 1 
ATOM   576  N  N   . LYS A  1 71  ? 29.99100 30.93001  -1.30534  1.000 21.08607 ? 71  LYS A N   1 
ATOM   577  C  CA  . LYS A  1 71  ? 28.87323 30.51557  -0.46330  1.000 18.05062 ? 71  LYS A CA  1 
ATOM   578  C  C   . LYS A  1 71  ? 27.59498 30.95120  -1.16938  1.000 17.50488 ? 71  LYS A C   1 
ATOM   579  O  O   . LYS A  1 71  ? 27.22793 32.12822  -1.14197  1.000 20.72561 ? 71  LYS A O   1 
ATOM   580  C  CB  . LYS A  1 71  ? 28.98483 31.11791  0.93322   1.000 20.69361 ? 71  LYS A CB  1 
ATOM   581  C  CG  . LYS A  1 71  ? 27.92385 30.62466  1.90427   1.000 20.97405 ? 71  LYS A CG  1 
ATOM   582  C  CD  . LYS A  1 71  ? 28.20348 31.10425  3.31767   1.000 18.56535 ? 71  LYS A CD  1 
ATOM   583  C  CE  . LYS A  1 71  ? 27.22833 30.49549  4.31041   1.000 18.94631 ? 71  LYS A CE  1 
ATOM   584  N  NZ  . LYS A  1 71  ? 27.53888 30.90143  5.70804   1.000 18.89817 ? 71  LYS A NZ  1 
ATOM   585  N  N   . TRP A  1 72  ? 26.92575 29.99922  -1.81606  1.000 20.11617 ? 72  TRP A N   1 
ATOM   586  C  CA  . TRP A  1 72  ? 25.70794 30.28446  -2.56780  1.000 17.82669 ? 72  TRP A CA  1 
ATOM   587  C  C   . TRP A  1 72  ? 24.53060 30.31762  -1.60099  1.000 19.81702 ? 72  TRP A C   1 
ATOM   588  O  O   . TRP A  1 72  ? 24.13338 29.28172  -1.05889  1.000 21.40809 ? 72  TRP A O   1 
ATOM   589  C  CB  . TRP A  1 72  ? 25.49276 29.23850  -3.65764  1.000 16.51840 ? 72  TRP A CB  1 
ATOM   590  C  CG  . TRP A  1 72  ? 26.69009 28.99258  -4.52983  1.000 12.97756 ? 72  TRP A CG  1 
ATOM   591  C  CD1 . TRP A  1 72  ? 27.60404 27.98777  -4.40047  1.000 13.62230 ? 72  TRP A CD1 1 
ATOM   592  C  CD2 . TRP A  1 72  ? 27.09606 29.75876  -5.67139  1.000 13.16615 ? 72  TRP A CD2 1 
ATOM   593  N  NE1 . TRP A  1 72  ? 28.55473 28.08114  -5.38822  1.000 13.53496 ? 72  TRP A NE1 1 
ATOM   594  C  CE2 . TRP A  1 72  ? 28.26567 29.15988  -6.18171  1.000 13.84872 ? 72  TRP A CE2 1 
ATOM   595  C  CE3 . TRP A  1 72  ? 26.58489 30.89291  -6.31084  1.000 13.37122 ? 72  TRP A CE3 1 
ATOM   596  C  CZ2 . TRP A  1 72  ? 28.93303 29.65775  -7.30021  1.000 11.72999 ? 72  TRP A CZ2 1 
ATOM   597  C  CZ3 . TRP A  1 72  ? 27.24820 31.38500  -7.42088  1.000 12.00784 ? 72  TRP A CZ3 1 
ATOM   598  C  CH2 . TRP A  1 72  ? 28.40937 30.76799  -7.90403  1.000 11.45537 ? 72  TRP A CH2 1 
ATOM   599  N  N   . LEU A  1 73  ? 23.96665 31.50181  -1.38982  1.000 20.09065 ? 73  LEU A N   1 
ATOM   600  C  CA  . LEU A  1 73  ? 22.89207 31.69846  -0.42896  1.000 16.75371 ? 73  LEU A CA  1 
ATOM   601  C  C   . LEU A  1 73  ? 21.54578 31.75514  -1.13840  1.000 22.04309 ? 73  LEU A C   1 
ATOM   602  O  O   . LEU A  1 73  ? 21.40146 32.41466  -2.17192  1.000 22.66893 ? 73  LEU A O   1 
ATOM   603  C  CB  . LEU A  1 73  ? 23.11600 32.98188  0.37218   1.000 25.67709 ? 73  LEU A CB  1 
ATOM   604  C  CG  . LEU A  1 73  ? 24.44273 33.05127  1.13152   1.000 28.18579 ? 73  LEU A CG  1 
ATOM   605  C  CD1 . LEU A  1 73  ? 24.66551 34.44119  1.70864   1.000 21.18281 ? 73  LEU A CD1 1 
ATOM   606  C  CD2 . LEU A  1 73  ? 24.48331 31.99463  2.22794   1.000 22.59654 ? 73  LEU A CD2 1 
ATOM   607  N  N   . ASN A  1 74  ? 20.56248 31.05996  -0.57363  1.000 24.27986 ? 74  ASN A N   1 
ATOM   608  C  CA  . ASN A  1 74  ? 19.20491 31.03403  -1.10151  1.000 22.41678 ? 74  ASN A CA  1 
ATOM   609  C  C   . ASN A  1 74  ? 18.35221 32.01505  -0.30592  1.000 24.11125 ? 74  ASN A C   1 
ATOM   610  O  O   . ASN A  1 74  ? 18.15439 31.83508  0.90057   1.000 28.58053 ? 74  ASN A O   1 
ATOM   611  C  CB  . ASN A  1 74  ? 18.62268 29.62044  -1.02862  1.000 22.88563 ? 74  ASN A CB  1 
ATOM   612  C  CG  . ASN A  1 74  ? 17.25908 29.49954  -1.70309  1.000 20.19808 ? 74  ASN A CG  1 
ATOM   613  O  OD1 . ASN A  1 74  ? 16.43145 30.40934  -1.64612  1.000 23.98129 ? 74  ASN A OD1 1 
ATOM   614  N  ND2 . ASN A  1 74  ? 17.02059 28.35984  -2.33907  1.000 17.03135 ? 74  ASN A ND2 1 
ATOM   615  N  N   . LYS A  1 75  ? 17.85074 33.04876  -0.98426  1.000 20.55633 ? 75  LYS A N   1 
ATOM   616  C  CA  . LYS A  1 75  ? 16.93047 34.01340  -0.39269  1.000 23.75575 ? 75  LYS A CA  1 
ATOM   617  C  C   . LYS A  1 75  ? 15.65423 34.11866  -1.21815  1.000 23.61715 ? 75  LYS A C   1 
ATOM   618  O  O   . LYS A  1 75  ? 15.01110 35.17122  -1.24955  1.000 22.64861 ? 75  LYS A O   1 
ATOM   619  C  CB  . LYS A  1 75  ? 17.58779 35.38569  -0.24831  1.000 21.07657 ? 75  LYS A CB  1 
ATOM   620  C  CG  . LYS A  1 75  ? 18.70053 35.44106  0.78350   1.000 21.36554 ? 75  LYS A CG  1 
ATOM   621  C  CD  . LYS A  1 75  ? 18.17352 35.15611  2.17871   1.000 28.12810 ? 75  LYS A CD  1 
ATOM   622  C  CE  . LYS A  1 75  ? 19.25739 35.35075  3.22561   1.000 36.05378 ? 75  LYS A CE  1 
ATOM   623  N  NZ  . LYS A  1 75  ? 18.75573 35.08320  4.60158   1.000 39.34036 ? 75  LYS A NZ  1 
ATOM   624  N  N   . LEU A  1 76  ? 15.28077 33.03581  -1.89160  1.000 21.24592 ? 76  LEU A N   1 
ATOM   625  C  CA  . LEU A  1 76  ? 14.12546 32.98653  -2.77146  1.000 18.44443 ? 76  LEU A CA  1 
ATOM   626  C  C   . LEU A  1 76  ? 12.86444 32.64883  -1.98804  1.000 29.18003 ? 76  LEU A C   1 
ATOM   627  O  O   . LEU A  1 76  ? 12.93096 32.07223  -0.89741  1.000 33.70648 ? 76  LEU A O   1 
ATOM   628  C  CB  . LEU A  1 76  ? 14.35641 31.95281  -3.87255  1.000 22.94271 ? 76  LEU A CB  1 
ATOM   629  C  CG  . LEU A  1 76  ? 15.49216 32.27975  -4.84394  1.000 25.34952 ? 76  LEU A CG  1 
ATOM   630  C  CD1 . LEU A  1 76  ? 15.65124 31.18564  -5.88759  1.000 19.31900 ? 76  LEU A CD1 1 
ATOM   631  C  CD2 . LEU A  1 76  ? 15.24825 33.62560  -5.50778  1.000 18.06846 ? 76  LEU A CD2 1 
ATOM   632  N  N   . PRO A  1 77  ? 11.68424 33.00536  -2.51894  1.000 23.68413 ? 77  PRO A N   1 
ATOM   633  C  CA  . PRO A  1 77  ? 10.43228 32.69159  -1.81416  1.000 23.42632 ? 77  PRO A CA  1 
ATOM   634  C  C   . PRO A  1 77  ? 10.18686 31.19788  -1.66713  1.000 27.84343 ? 77  PRO A C   1 
ATOM   635  O  O   . PRO A  1 77  ? 10.94989 30.37445  -2.18239  1.000 20.41530 ? 77  PRO A O   1 
ATOM   636  C  CB  . PRO A  1 77  ? 9.35882  33.34263  -2.69673  1.000 22.59931 ? 77  PRO A CB  1 
ATOM   637  C  CG  . PRO A  1 77  ? 10.08166 34.38260  -3.47587  1.000 26.75454 ? 77  PRO A CG  1 
ATOM   638  C  CD  . PRO A  1 77  ? 11.45047 33.83479  -3.71333  1.000 19.92810 ? 77  PRO A CD  1 
ATOM   639  N  N   . ASP A  1 78  ? 9.11091  30.84128  -0.96454  1.000 27.26078 ? 78  ASP A N   1 
ATOM   640  C  CA  . ASP A  1 78  ? 8.77541  29.43967  -0.75389  1.000 31.09305 ? 78  ASP A CA  1 
ATOM   641  C  C   . ASP A  1 78  ? 8.06002  28.81772  -1.94550  1.000 31.48129 ? 78  ASP A C   1 
ATOM   642  O  O   . ASP A  1 78  ? 8.05281  27.58873  -2.07252  1.000 39.61492 ? 78  ASP A O   1 
ATOM   643  C  CB  . ASP A  1 78  ? 7.91437  29.29038  0.50362   1.000 46.37317 ? 78  ASP A CB  1 
ATOM   644  C  CG  . ASP A  1 78  ? 6.79572  30.31448  0.57097   1.000 49.75947 ? 78  ASP A CG  1 
ATOM   645  O  OD1 . ASP A  1 78  ? 6.74377  31.20186  -0.30749  1.000 44.84408 ? 78  ASP A OD1 1 
ATOM   646  O  OD2 . ASP A  1 78  ? 5.96946  30.23311  1.50454   1.000 48.32880 ? 78  ASP A OD2 1 
ATOM   647  N  N   . HIS A  1 79  ? 7.46596  29.62794  -2.81669  1.000 29.68043 ? 79  HIS A N   1 
ATOM   648  C  CA  . HIS A  1 79  ? 6.75894  29.13813  -3.98908  1.000 29.81656 ? 79  HIS A CA  1 
ATOM   649  C  C   . HIS A  1 79  ? 7.38334  29.71521  -5.25191  1.000 30.56939 ? 79  HIS A C   1 
ATOM   650  O  O   . HIS A  1 79  ? 7.89207  30.84042  -5.25636  1.000 27.22783 ? 79  HIS A O   1 
ATOM   651  C  CB  . HIS A  1 79  ? 5.26661  29.49615  -3.93289  1.000 38.71874 ? 79  HIS A CB  1 
ATOM   652  C  CG  . HIS A  1 79  ? 4.50511  28.75218  -2.87902  1.000 50.29989 ? 79  HIS A CG  1 
ATOM   653  N  ND1 . HIS A  1 79  ? 3.82834  27.57948  -3.13819  1.000 41.81684 ? 79  HIS A ND1 1 
ATOM   654  C  CD2 . HIS A  1 79  ? 4.31348  29.01371  -1.56402  1.000 44.23778 ? 79  HIS A CD2 1 
ATOM   655  C  CE1 . HIS A  1 79  ? 3.25235  27.15107  -2.02924  1.000 36.62722 ? 79  HIS A CE1 1 
ATOM   656  N  NE2 . HIS A  1 79  ? 3.53150  28.00297  -1.05914  1.000 45.30403 ? 79  HIS A NE2 1 
ATOM   657  N  N   . HIS A  1 80  ? 7.34249  28.92866  -6.32259  1.000 26.93802 ? 80  HIS A N   1 
ATOM   658  C  CA  . HIS A  1 80  ? 7.89293  29.32951  -7.60747  1.000 18.99884 ? 80  HIS A CA  1 
ATOM   659  C  C   . HIS A  1 80  ? 6.83430  30.05740  -8.42651  1.000 19.94994 ? 80  HIS A C   1 
ATOM   660  O  O   . HIS A  1 80  ? 5.63794  29.77684  -8.31868  1.000 29.56598 ? 80  HIS A O   1 
ATOM   661  C  CB  . HIS A  1 80  ? 8.39991  28.10654  -8.37551  1.000 25.58290 ? 80  HIS A CB  1 
ATOM   662  C  CG  . HIS A  1 80  ? 9.58168  28.38442  -9.25176  1.000 20.56603 ? 80  HIS A CG  1 
ATOM   663  N  ND1 . HIS A  1 80  ? 9.54616  29.29462  -10.28578 1.000 20.78552 ? 80  HIS A ND1 1 
ATOM   664  C  CD2 . HIS A  1 80  ? 10.83130 27.86259  -9.25310  1.000 18.04690 ? 80  HIS A CD2 1 
ATOM   665  C  CE1 . HIS A  1 80  ? 10.72468 29.32694  -10.88199 1.000 21.51739 ? 80  HIS A CE1 1 
ATOM   666  N  NE2 . HIS A  1 80  ? 11.52220 28.46648  -10.27528 1.000 19.91244 ? 80  HIS A NE2 1 
ATOM   667  N  N   . PHE A  1 81  ? 7.28381  31.00157  -9.24949  1.000 20.19980 ? 81  PHE A N   1 
ATOM   668  C  CA  . PHE A  1 81  ? 6.38079  31.73703  -10.12478 1.000 19.73168 ? 81  PHE A CA  1 
ATOM   669  C  C   . PHE A  1 81  ? 6.23401  31.09310  -11.49766 1.000 22.76230 ? 81  PHE A C   1 
ATOM   670  O  O   . PHE A  1 81  ? 5.46173  31.59351  -12.32216 1.000 20.33074 ? 81  PHE A O   1 
ATOM   671  C  CB  . PHE A  1 81  ? 6.84617  33.19266  -10.27382 1.000 18.09120 ? 81  PHE A CB  1 
ATOM   672  C  CG  . PHE A  1 81  ? 8.13507  33.35373  -11.03151 1.000 19.45789 ? 81  PHE A CG  1 
ATOM   673  C  CD1 . PHE A  1 81  ? 9.35508  33.21385  -10.39048 1.000 16.80615 ? 81  PHE A CD1 1 
ATOM   674  C  CD2 . PHE A  1 81  ? 8.12553  33.67108  -12.38117 1.000 18.21384 ? 81  PHE A CD2 1 
ATOM   675  C  CE1 . PHE A  1 81  ? 10.54210 33.37234  -11.08406 1.000 15.88993 ? 81  PHE A CE1 1 
ATOM   676  C  CE2 . PHE A  1 81  ? 9.30779  33.83058  -13.08014 1.000 18.74001 ? 81  PHE A CE2 1 
ATOM   677  C  CZ  . PHE A  1 81  ? 10.51801 33.68106  -12.43053 1.000 18.61131 ? 81  PHE A CZ  1 
ATOM   678  N  N   . LEU A  1 82  ? 6.95070  29.99958  -11.75998 1.000 23.63527 ? 82  LEU A N   1 
ATOM   679  C  CA  . LEU A  1 82  ? 6.86245  29.24788  -12.99981 1.000 20.92472 ? 82  LEU A CA  1 
ATOM   680  C  C   . LEU A  1 82  ? 6.15148  27.91662  -12.76431 1.000 18.34985 ? 82  LEU A C   1 
ATOM   681  O  O   . LEU A  1 82  ? 6.19110  27.37645  -11.65427 1.000 19.33491 ? 82  LEU A O   1 
ATOM   682  C  CB  . LEU A  1 82  ? 8.25622  28.99020  -13.58613 1.000 20.71642 ? 82  LEU A CB  1 
ATOM   683  C  CG  . LEU A  1 82  ? 9.01207  30.22730  -14.07554 1.000 19.79533 ? 82  LEU A CG  1 
ATOM   684  C  CD1 . LEU A  1 82  ? 10.35321 29.83375  -14.67386 1.000 20.07420 ? 82  LEU A CD1 1 
ATOM   685  C  CD2 . LEU A  1 82  ? 8.18030  31.00249  -15.08514 1.000 16.80340 ? 82  LEU A CD2 1 
ATOM   686  N  N   . PRO A  1 83  ? 5.48929  27.36559  -13.78248 1.000 17.58469 ? 83  PRO A N   1 
ATOM   687  C  CA  . PRO A  1 83  ? 4.70467  26.13523  -13.58081 1.000 19.68582 ? 83  PRO A CA  1 
ATOM   688  C  C   . PRO A  1 83  ? 5.58988  24.96148  -13.18975 1.000 23.68181 ? 83  PRO A C   1 
ATOM   689  O  O   . PRO A  1 83  ? 6.46841  24.54216  -13.94678 1.000 27.29391 ? 83  PRO A O   1 
ATOM   690  C  CB  . PRO A  1 83  ? 4.04108  25.91258  -14.94573 1.000 24.44305 ? 83  PRO A CB  1 
ATOM   691  C  CG  . PRO A  1 83  ? 4.11465  27.23419  -15.63990 1.000 21.12230 ? 83  PRO A CG  1 
ATOM   692  C  CD  . PRO A  1 83  ? 5.37047  27.87519  -15.15848 1.000 20.34324 ? 83  PRO A CD  1 
ATOM   693  N  N   . VAL A  1 84  ? 5.34393  24.42452  -11.99816 1.000 18.66031 ? 84  VAL A N   1 
ATOM   694  C  CA  . VAL A  1 84  ? 6.11029  23.30737  -11.45758 1.000 21.08065 ? 84  VAL A CA  1 
ATOM   695  C  C   . VAL A  1 84  ? 5.32191  22.02377  -11.68113 1.000 27.12498 ? 84  VAL A C   1 
ATOM   696  O  O   . VAL A  1 84  ? 4.16991  21.90804  -11.24535 1.000 26.04162 ? 84  VAL A O   1 
ATOM   697  C  CB  . VAL A  1 84  ? 6.41922  23.50816  -9.96549  1.000 21.22385 ? 84  VAL A CB  1 
ATOM   698  C  CG1 . VAL A  1 84  ? 6.94313  22.21702  -9.35380  1.000 18.35491 ? 84  VAL A CG1 1 
ATOM   699  C  CG2 . VAL A  1 84  ? 7.42240  24.63289  -9.77726  1.000 22.01378 ? 84  VAL A CG2 1 
ATOM   700  N  N   . ASP A  1 85  ? 5.94021  21.05938  -12.35950 1.000 22.13645 ? 85  ASP A N   1 
ATOM   701  C  CA  . ASP A  1 85  ? 5.35563  19.73283  -12.52668 1.000 21.18813 ? 85  ASP A CA  1 
ATOM   702  C  C   . ASP A  1 85  ? 5.68934  18.90537  -11.29092 1.000 27.89052 ? 85  ASP A C   1 
ATOM   703  O  O   . ASP A  1 85  ? 6.84536  18.52057  -11.08480 1.000 28.55967 ? 85  ASP A O   1 
ATOM   704  C  CB  . ASP A  1 85  ? 5.88232  19.07516  -13.80020 1.000 25.02527 ? 85  ASP A CB  1 
ATOM   705  C  CG  . ASP A  1 85  ? 5.17819  17.76368  -14.12766 1.000 29.44431 ? 85  ASP A CG  1 
ATOM   706  O  OD1 . ASP A  1 85  ? 4.94294  16.94731  -13.21108 1.000 26.81748 ? 85  ASP A OD1 1 
ATOM   707  O  OD2 . ASP A  1 85  ? 4.86364  17.54503  -15.31624 1.000 27.23494 ? 85  ASP A OD2 1 
ATOM   708  N  N   . HIS A  1 86  ? 4.67756  18.62381  -10.47094 1.000 29.48845 ? 86  HIS A N   1 
ATOM   709  C  CA  . HIS A  1 86  ? 4.85607  17.88728  -9.22782  1.000 34.02425 ? 86  HIS A CA  1 
ATOM   710  C  C   . HIS A  1 86  ? 4.78315  16.37454  -9.41749  1.000 29.66836 ? 86  HIS A C   1 
ATOM   711  O  O   . HIS A  1 86  ? 4.61487  15.64644  -8.43236  1.000 32.89083 ? 86  HIS A O   1 
ATOM   712  C  CB  . HIS A  1 86  ? 3.80917  18.32607  -8.19958  1.000 32.37140 ? 86  HIS A CB  1 
ATOM   713  C  CG  . HIS A  1 86  ? 3.67169  19.81114  -8.06620  1.000 34.26146 ? 86  HIS A CG  1 
ATOM   714  N  ND1 . HIS A  1 86  ? 4.42029  20.55220  -7.17704  1.000 29.53117 ? 86  HIS A ND1 1 
ATOM   715  C  CD2 . HIS A  1 86  ? 2.86376  20.69199  -8.70292  1.000 31.91047 ? 86  HIS A CD2 1 
ATOM   716  C  CE1 . HIS A  1 86  ? 4.08307  21.82594  -7.27539  1.000 33.83093 ? 86  HIS A CE1 1 
ATOM   717  N  NE2 . HIS A  1 86  ? 3.14039  21.93777  -8.19390  1.000 30.55706 ? 86  HIS A NE2 1 
ATOM   718  N  N   . THR A  1 87  ? 4.90047  15.88398  -10.65350 1.000 27.27862 ? 87  THR A N   1 
ATOM   719  C  CA  . THR A  1 87  ? 4.70926  14.46748  -10.93496 1.000 25.95575 ? 87  THR A CA  1 
ATOM   720  C  C   . THR A  1 87  ? 5.91276  13.79065  -11.57679 1.000 28.54704 ? 87  THR A C   1 
ATOM   721  O  O   . THR A  1 87  ? 5.83254  12.59550  -11.88274 1.000 30.70293 ? 87  THR A O   1 
ATOM   722  C  CB  . THR A  1 87  ? 3.49040  14.25775  -11.84731 1.000 29.84574 ? 87  THR A CB  1 
ATOM   723  O  OG1 . THR A  1 87  ? 3.89538  14.35790  -13.21854 1.000 36.75416 ? 87  THR A OG1 1 
ATOM   724  C  CG2 . THR A  1 87  ? 2.41903  15.30136  -11.56990 1.000 32.57406 ? 87  THR A CG2 1 
ATOM   725  N  N   . ILE A  1 88  ? 7.01875  14.50051  -11.79527 1.000 29.83713 ? 88  ILE A N   1 
ATOM   726  C  CA  . ILE A  1 88  ? 8.14614  13.91078  -12.51093 1.000 33.26007 ? 88  ILE A CA  1 
ATOM   727  C  C   . ILE A  1 88  ? 9.15989  13.33828  -11.52862 1.000 29.82492 ? 88  ILE A C   1 
ATOM   728  O  O   . ILE A  1 88  ? 9.81650  12.33258  -11.81974 1.000 45.42448 ? 88  ILE A O   1 
ATOM   729  C  CB  . ILE A  1 88  ? 8.80467  14.92835  -13.46233 1.000 28.64741 ? 88  ILE A CB  1 
ATOM   730  C  CG1 . ILE A  1 88  ? 9.20985  16.19976  -12.71551 1.000 29.78356 ? 88  ILE A CG1 1 
ATOM   731  C  CG2 . ILE A  1 88  ? 7.86589  15.25832  -14.61544 1.000 25.30929 ? 88  ILE A CG2 1 
ATOM   732  C  CD1 . ILE A  1 88  ? 9.93463  17.20670  -13.58614 1.000 17.72970 ? 88  ILE A CD1 1 
ATOM   733  N  N   . HIS A  1 89  ? 9.29315  13.96368  -10.36344 1.000 30.54286 ? 89  HIS A N   1 
ATOM   734  C  CA  . HIS A  1 89  ? 10.20712 13.47305  -9.33500  1.000 31.41923 ? 89  HIS A CA  1 
ATOM   735  C  C   . HIS A  1 89  ? 9.68677  13.79512  -7.93759  1.000 41.52462 ? 89  HIS A C   1 
ATOM   736  O  O   . HIS A  1 89  ? 9.04902  12.96100  -7.29339  1.000 43.44588 ? 89  HIS A O   1 
ATOM   737  C  CB  . HIS A  1 89  ? 11.60671 14.06676  -9.52274  1.000 34.24703 ? 89  HIS A CB  1 
ATOM   738  C  CG  . HIS A  1 89  ? 12.35253 13.50459  -10.69356 1.000 37.33278 ? 89  HIS A CG  1 
ATOM   739  N  ND1 . HIS A  1 89  ? 12.95488 12.26485  -10.66696 1.000 39.47691 ? 89  HIS A ND1 1 
ATOM   740  C  CD2 . HIS A  1 89  ? 12.59632 14.01455  -11.92426 1.000 34.08030 ? 89  HIS A CD2 1 
ATOM   741  C  CE1 . HIS A  1 89  ? 13.53521 12.03451  -11.83143 1.000 39.95682 ? 89  HIS A CE1 1 
ATOM   742  N  NE2 . HIS A  1 89  ? 13.33276 13.08061  -12.61213 1.000 29.93333 ? 89  HIS A NE2 1 
ATOM   743  N  N   . GLU A  1 97  ? 8.02498  23.70741  -4.12778  1.000 41.83068 ? 97  GLU A N   1 
ATOM   744  C  CA  . GLU A  1 97  ? 8.98920  24.56053  -3.44210  1.000 44.49565 ? 97  GLU A CA  1 
ATOM   745  C  C   . GLU A  1 97  ? 10.03669 25.10243  -4.40885  1.000 41.05992 ? 97  GLU A C   1 
ATOM   746  O  O   . GLU A  1 97  ? 10.09241 24.70091  -5.57211  1.000 25.15967 ? 97  GLU A O   1 
ATOM   747  C  CB  . GLU A  1 97  ? 9.67792  23.79720  -2.30460  1.000 37.16921 ? 97  GLU A CB  1 
ATOM   748  C  CG  . GLU A  1 97  ? 8.78636  23.51101  -1.10390  1.000 46.72810 ? 97  GLU A CG  1 
ATOM   749  C  CD  . GLU A  1 97  ? 7.91762  22.28059  -1.29098  1.000 55.38448 ? 97  GLU A CD  1 
ATOM   750  O  OE1 . GLU A  1 97  ? 8.42508  21.26301  -1.80877  1.000 53.40394 ? 97  GLU A OE1 1 
ATOM   751  O  OE2 . GLU A  1 97  ? 6.72551  22.33153  -0.92020  1.000 55.83077 ? 97  GLU A OE2 1 
ATOM   752  N  N   . VAL A  1 98  ? 10.86720 26.02052  -3.91689  1.000 42.75516 ? 98  VAL A N   1 
ATOM   753  C  CA  . VAL A  1 98  ? 11.96891 26.56026  -4.70466  1.000 33.15992 ? 98  VAL A CA  1 
ATOM   754  C  C   . VAL A  1 98  ? 13.27651 25.97105  -4.19419  1.000 29.11641 ? 98  VAL A C   1 
ATOM   755  O  O   . VAL A  1 98  ? 13.87793 26.48649  -3.24502  1.000 25.91302 ? 98  VAL A O   1 
ATOM   756  C  CB  . VAL A  1 98  ? 11.99799 28.09832  -4.65896  1.000 28.31677 ? 98  VAL A CB  1 
ATOM   757  C  CG1 . VAL A  1 98  ? 13.13268 28.62721  -5.51756  1.000 22.21994 ? 98  VAL A CG1 1 
ATOM   758  C  CG2 . VAL A  1 98  ? 10.67042 28.66438  -5.12904  1.000 29.13935 ? 98  VAL A CG2 1 
ATOM   759  N  N   . LYS A  1 99  ? 13.71473 24.88011  -4.81414  1.000 30.87159 ? 99  LYS A N   1 
ATOM   760  C  CA  . LYS A  1 99  ? 14.97966 24.24595  -4.47709  1.000 23.75129 ? 99  LYS A CA  1 
ATOM   761  C  C   . LYS A  1 99  ? 16.07788 24.79374  -5.37769  1.000 21.38675 ? 99  LYS A C   1 
ATOM   762  O  O   . LYS A  1 99  ? 15.84348 25.07858  -6.55562  1.000 19.00377 ? 99  LYS A O   1 
ATOM   763  C  CB  . LYS A  1 99  ? 14.87125 22.72920  -4.63171  1.000 24.81012 ? 99  LYS A CB  1 
ATOM   764  C  CG  . LYS A  1 99  ? 13.65211 22.13711  -3.94476  1.000 28.23728 ? 99  LYS A CG  1 
ATOM   765  C  CD  . LYS A  1 99  ? 13.42103 20.69410  -4.35530  1.000 25.54708 ? 99  LYS A CD  1 
ATOM   766  C  CE  . LYS A  1 99  ? 12.23408 20.10188  -3.61445  1.000 39.97702 ? 99  LYS A CE  1 
ATOM   767  N  NZ  . LYS A  1 99  ? 11.00361 20.92168  -3.79679  1.000 44.69414 ? 99  LYS A NZ  1 
ATOM   768  N  N   . THR A  1 100 ? 17.27653 24.95148  -4.81668  1.000 19.85838 ? 100 THR A N   1 
ATOM   769  C  CA  . THR A  1 100 ? 18.38046 25.56900  -5.53815  1.000 16.77163 ? 100 THR A CA  1 
ATOM   770  C  C   . THR A  1 100 ? 19.68847 24.85466  -5.23648  1.000 19.07058 ? 100 THR A C   1 
ATOM   771  O  O   . THR A  1 100 ? 19.92816 24.42447  -4.10465  1.000 19.00734 ? 100 THR A O   1 
ATOM   772  C  CB  . THR A  1 100 ? 18.53573 27.05408  -5.17885  1.000 14.74823 ? 100 THR A CB  1 
ATOM   773  O  OG1 . THR A  1 100 ? 18.63197 27.19556  -3.75656  1.000 18.61137 ? 100 THR A OG1 1 
ATOM   774  C  CG2 . THR A  1 100 ? 17.36132 27.87334  -5.70079  1.000 15.78307 ? 100 THR A CG2 1 
ATOM   775  N  N   . VAL A  1 101 ? 20.53048 24.74450  -6.26036  1.000 14.57927 ? 101 VAL A N   1 
ATOM   776  C  CA  . VAL A  1 101 ? 21.91048 24.29697  -6.10778  1.000 14.16824 ? 101 VAL A CA  1 
ATOM   777  C  C   . VAL A  1 101 ? 22.68551 24.80386  -7.31599  1.000 13.04627 ? 101 VAL A C   1 
ATOM   778  O  O   . VAL A  1 101 ? 22.19330 24.76297  -8.44711  1.000 15.42667 ? 101 VAL A O   1 
ATOM   779  C  CB  . VAL A  1 101 ? 21.99982 22.75865  -5.94961  1.000 16.69903 ? 101 VAL A CB  1 
ATOM   780  C  CG1 . VAL A  1 101 ? 21.46014 22.04588  -7.17880  1.000 12.75909 ? 101 VAL A CG1 1 
ATOM   781  C  CG2 . VAL A  1 101 ? 23.43042 22.33264  -5.65778  1.000 14.97846 ? 101 VAL A CG2 1 
ATOM   782  N  N   . VAL A  1 102 ? 23.89150 25.30838  -7.06807  1.000 10.33592 ? 102 VAL A N   1 
ATOM   783  C  CA  . VAL A  1 102 ? 24.66845 26.01547  -8.08082  1.000 14.09361 ? 102 VAL A CA  1 
ATOM   784  C  C   . VAL A  1 102 ? 25.74238 25.08911  -8.63093  1.000 11.40973 ? 102 VAL A C   1 
ATOM   785  O  O   . VAL A  1 102 ? 26.52623 24.50952  -7.86947  1.000 11.67915 ? 102 VAL A O   1 
ATOM   786  C  CB  . VAL A  1 102 ? 25.29164 27.29951  -7.50878  1.000 15.52922 ? 102 VAL A CB  1 
ATOM   787  C  CG1 . VAL A  1 102 ? 26.08776 28.02109  -8.58450  1.000 13.33420 ? 102 VAL A CG1 1 
ATOM   788  C  CG2 . VAL A  1 102 ? 24.20722 28.20509  -6.94451  1.000 13.81676 ? 102 VAL A CG2 1 
ATOM   789  N  N   . HIS A  1 103 ? 25.78651 24.96095  -9.95483  1.000 10.90360 ? 103 HIS A N   1 
ATOM   790  C  CA  . HIS A  1 103 ? 26.76334 24.12999  -10.64338 1.000 12.18880 ? 103 HIS A CA  1 
ATOM   791  C  C   . HIS A  1 103 ? 27.62224 24.99763  -11.55026 1.000 12.63114 ? 103 HIS A C   1 
ATOM   792  O  O   . HIS A  1 103 ? 27.09609 25.79915  -12.32951 1.000 15.25962 ? 103 HIS A O   1 
ATOM   793  C  CB  . HIS A  1 103 ? 26.07810 23.03719  -11.46628 1.000 17.10540 ? 103 HIS A CB  1 
ATOM   794  C  CG  . HIS A  1 103 ? 26.99270 22.35032  -12.43199 1.000 20.00660 ? 103 HIS A CG  1 
ATOM   795  N  ND1 . HIS A  1 103 ? 28.09326 21.62529  -12.02771 1.000 17.54219 ? 103 HIS A ND1 1 
ATOM   796  C  CD2 . HIS A  1 103 ? 26.97576 22.28573  -13.78435 1.000 15.59364 ? 103 HIS A CD2 1 
ATOM   797  C  CE1 . HIS A  1 103 ? 28.71199 21.13995  -13.08917 1.000 15.54773 ? 103 HIS A CE1 1 
ATOM   798  N  NE2 . HIS A  1 103 ? 28.05352 21.52508  -14.16743 1.000 14.96737 ? 103 HIS A NE2 1 
ATOM   799  N  N   . LEU A  1 104 ? 28.93919 24.83409  -11.44873 1.000 14.13040 ? 104 LEU A N   1 
ATOM   800  C  CA  . LEU A  1 104 ? 29.88291 25.51578  -12.33266 1.000 12.79126 ? 104 LEU A CA  1 
ATOM   801  C  C   . LEU A  1 104 ? 30.07425 24.64064  -13.56493 1.000 13.34626 ? 104 LEU A C   1 
ATOM   802  O  O   . LEU A  1 104 ? 30.80548 23.64768  -13.53004 1.000 11.83592 ? 104 LEU A O   1 
ATOM   803  C  CB  . LEU A  1 104 ? 31.20266 25.78176  -11.61729 1.000 12.10580 ? 104 LEU A CB  1 
ATOM   804  C  CG  . LEU A  1 104 ? 32.28619 26.49370  -12.42996 1.000 12.73801 ? 104 LEU A CG  1 
ATOM   805  C  CD1 . LEU A  1 104 ? 31.79197 27.84334  -12.91976 1.000 10.74298 ? 104 LEU A CD1 1 
ATOM   806  C  CD2 . LEU A  1 104 ? 33.55510 26.65233  -11.60937 1.000 10.55541 ? 104 LEU A CD2 1 
ATOM   807  N  N   . HIS A  1 105 ? 29.40748 25.00731  -14.65688 1.000 15.09139 ? 105 HIS A N   1 
ATOM   808  C  CA  . HIS A  1 105 ? 29.44323 24.20926  -15.87590 1.000 10.66223 ? 105 HIS A CA  1 
ATOM   809  C  C   . HIS A  1 105 ? 30.84775 24.21690  -16.46826 1.000 13.59905 ? 105 HIS A C   1 
ATOM   810  O  O   . HIS A  1 105 ? 31.41044 25.28310  -16.74021 1.000 10.43808 ? 105 HIS A O   1 
ATOM   811  C  CB  . HIS A  1 105 ? 28.43219 24.74658  -16.88460 1.000 9.15906  ? 105 HIS A CB  1 
ATOM   812  C  CG  . HIS A  1 105 ? 28.32269 23.92033  -18.12732 1.000 12.41877 ? 105 HIS A CG  1 
ATOM   813  N  ND1 . HIS A  1 105 ? 27.25198 23.08980  -18.37583 1.000 12.05433 ? 105 HIS A ND1 1 
ATOM   814  C  CD2 . HIS A  1 105 ? 29.15287 23.79138  -19.18909 1.000 12.41515 ? 105 HIS A CD2 1 
ATOM   815  C  CE1 . HIS A  1 105 ? 27.42408 22.48839  -19.53898 1.000 14.39393 ? 105 HIS A CE1 1 
ATOM   816  N  NE2 . HIS A  1 105 ? 28.57033 22.89630  -20.05300 1.000 17.82090 ? 105 HIS A NE2 1 
ATOM   817  N  N   . GLY A  1 106 ? 31.40872 23.02617  -16.67432 1.000 15.49187 ? 106 GLY A N   1 
ATOM   818  C  CA  . GLY A  1 106 ? 32.74428 22.88563  -17.21133 1.000 10.13239 ? 106 GLY A CA  1 
ATOM   819  C  C   . GLY A  1 106 ? 33.85980 22.99184  -16.19644 1.000 11.37403 ? 106 GLY A C   1 
ATOM   820  O  O   . GLY A  1 106 ? 35.02867 22.82135  -16.56631 1.000 14.14592 ? 106 GLY A O   1 
ATOM   821  N  N   . GLY A  1 107 ? 33.54425 23.26026  -14.93200 1.000 11.41624 ? 107 GLY A N   1 
ATOM   822  C  CA  . GLY A  1 107 ? 34.58135 23.43732  -13.93153 1.000 13.50981 ? 107 GLY A CA  1 
ATOM   823  C  C   . GLY A  1 107 ? 35.15713 22.10901  -13.46531 1.000 14.38875 ? 107 GLY A C   1 
ATOM   824  O  O   . GLY A  1 107 ? 34.43827 21.13518  -13.24138 1.000 16.38751 ? 107 GLY A O   1 
ATOM   825  N  N   . ARG A  1 108 ? 36.48062 22.07953  -13.32961 1.000 12.47497 ? 108 ARG A N   1 
ATOM   826  C  CA  . ARG A  1 108 ? 37.18011 20.92849  -12.76327 1.000 15.79483 ? 108 ARG A CA  1 
ATOM   827  C  C   . ARG A  1 108 ? 37.02463 21.00837  -11.25057 1.000 14.18694 ? 108 ARG A C   1 
ATOM   828  O  O   . ARG A  1 108 ? 37.86203 21.56734  -10.54142 1.000 22.02109 ? 108 ARG A O   1 
ATOM   829  C  CB  . ARG A  1 108 ? 38.64278 20.91963  -13.18923 1.000 18.09171 ? 108 ARG A CB  1 
ATOM   830  C  CG  . ARG A  1 108 ? 39.41445 19.70614  -12.70768 1.000 22.25068 ? 108 ARG A CG  1 
ATOM   831  C  CD  . ARG A  1 108 ? 40.82473 19.67067  -13.27295 1.000 28.39262 ? 108 ARG A CD  1 
ATOM   832  N  NE  . ARG A  1 108 ? 40.83727 19.45553  -14.71472 1.000 28.22465 ? 108 ARG A NE  1 
ATOM   833  C  CZ  . ARG A  1 108 ? 41.80241 18.81985  -15.36525 1.000 39.36521 ? 108 ARG A CZ  1 
ATOM   834  N  NH1 . ARG A  1 108 ? 42.83602 18.29396  -14.72699 1.000 35.90592 ? 108 ARG A NH1 1 
ATOM   835  N  NH2 . ARG A  1 108 ? 41.72443 18.70063  -16.68783 1.000 37.29223 ? 108 ARG A NH2 1 
ATOM   836  N  N   . THR A  1 109 ? 35.92869 20.44142  -10.75120 1.000 15.99542 ? 109 THR A N   1 
ATOM   837  C  CA  . THR A  1 109 ? 35.51041 20.63162  -9.37580  1.000 15.27613 ? 109 THR A CA  1 
ATOM   838  C  C   . THR A  1 109 ? 35.36981 19.29587  -8.65780  1.000 17.38818 ? 109 THR A C   1 
ATOM   839  O  O   . THR A  1 109 ? 34.86423 18.33122  -9.24178  1.000 18.75661 ? 109 THR A O   1 
ATOM   840  C  CB  . THR A  1 109 ? 34.16574 21.37269  -9.32178  1.000 13.63384 ? 109 THR A CB  1 
ATOM   841  O  OG1 . THR A  1 109 ? 34.16904 22.43833  -10.27917 1.000 12.25468 ? 109 THR A OG1 1 
ATOM   842  C  CG2 . THR A  1 109 ? 33.91773 21.94445  -7.93436  1.000 15.44055 ? 109 THR A CG2 1 
ATOM   843  N  N   . PRO A  1 110 ? 35.81283 19.20362  -7.40486  1.000 22.55079 ? 110 PRO A N   1 
ATOM   844  C  CA  . PRO A  1 110 ? 35.50318 18.01885  -6.61287  1.000 17.59832 ? 110 PRO A CA  1 
ATOM   845  C  C   . PRO A  1 110 ? 34.00501 17.84714  -6.48414  1.000 15.93927 ? 110 PRO A C   1 
ATOM   846  O  O   . PRO A  1 110 ? 33.24059 18.82846  -6.55461  1.000 16.05654 ? 110 PRO A O   1 
ATOM   847  C  CB  . PRO A  1 110 ? 36.15825 18.32125  -5.25751  1.000 15.88129 ? 110 PRO A CB  1 
ATOM   848  C  CG  . PRO A  1 110 ? 37.27054 19.25494  -5.58736  1.000 12.62335 ? 110 PRO A CG  1 
ATOM   849  C  CD  . PRO A  1 110 ? 36.75311 20.10321  -6.71424  1.000 14.50644 ? 110 PRO A CD  1 
ATOM   850  N  N   . PRO A  1 111 ? 33.53230 16.61192  -6.29244  1.000 20.77460 ? 111 PRO A N   1 
ATOM   851  C  CA  . PRO A  1 111 ? 32.07833 16.37263  -6.31958  1.000 17.86921 ? 111 PRO A CA  1 
ATOM   852  C  C   . PRO A  1 111 ? 31.30982 17.10010  -5.22930  1.000 18.22585 ? 111 PRO A C   1 
ATOM   853  O  O   . PRO A  1 111 ? 30.11945 17.38706  -5.41209  1.000 15.67943 ? 111 PRO A O   1 
ATOM   854  C  CB  . PRO A  1 111 ? 31.97472 14.84879  -6.16159  1.000 16.46184 ? 111 PRO A CB  1 
ATOM   855  C  CG  . PRO A  1 111 ? 33.24840 14.44844  -5.49116  1.000 15.91485 ? 111 PRO A CG  1 
ATOM   856  C  CD  . PRO A  1 111 ? 34.29361 15.37896  -6.02754  1.000 15.12596 ? 111 PRO A CD  1 
ATOM   857  N  N   . ASP A  1 112 ? 31.95179 17.41551  -4.10257  1.000 17.82077 ? 112 ASP A N   1 
ATOM   858  C  CA  . ASP A  1 112 ? 31.25478 18.08237  -3.00846  1.000 23.69148 ? 112 ASP A CA  1 
ATOM   859  C  C   . ASP A  1 112 ? 30.91360 19.53315  -3.32518  1.000 24.29446 ? 112 ASP A C   1 
ATOM   860  O  O   . ASP A  1 112 ? 30.08320 20.12515  -2.62673  1.000 20.98460 ? 112 ASP A O   1 
ATOM   861  C  CB  . ASP A  1 112 ? 32.09458 18.00462  -1.73282  1.000 24.51415 ? 112 ASP A CB  1 
ATOM   862  C  CG  . ASP A  1 112 ? 33.55071 18.35178  -1.97010  1.000 38.56288 ? 112 ASP A CG  1 
ATOM   863  O  OD1 . ASP A  1 112 ? 34.00268 19.40960  -1.48113  1.000 41.00889 ? 112 ASP A OD1 1 
ATOM   864  O  OD2 . ASP A  1 112 ? 34.24114 17.56771  -2.65676  1.000 39.57427 ? 112 ASP A OD2 1 
ATOM   865  N  N   . SER A  1 113 ? 31.52918 20.11663  -4.35480  1.000 16.71065 ? 113 SER A N   1 
ATOM   866  C  CA  . SER A  1 113 ? 31.24242 21.48695  -4.76277  1.000 19.96791 ? 113 SER A CA  1 
ATOM   867  C  C   . SER A  1 113 ? 30.75447 21.57578  -6.20297  1.000 20.17113 ? 113 SER A C   1 
ATOM   868  O  O   . SER A  1 113 ? 30.68862 22.67955  -6.75747  1.000 19.05346 ? 113 SER A O   1 
ATOM   869  C  CB  . SER A  1 113 ? 32.48015 22.37152  -4.57936  1.000 16.39365 ? 113 SER A CB  1 
ATOM   870  O  OG  . SER A  1 113 ? 32.81358 22.51450  -3.21097  1.000 18.90359 ? 113 SER A OG  1 
ATOM   871  N  N   . ASP A  1 114 ? 30.40758 20.44701  -6.82214  1.000 15.95096 ? 114 ASP A N   1 
ATOM   872  C  CA  . ASP A  1 114 ? 30.01327 20.44458  -8.22450  1.000 15.71260 ? 114 ASP A CA  1 
ATOM   873  C  C   . ASP A  1 114 ? 28.55574 20.83881  -8.42841  1.000 19.55558 ? 114 ASP A C   1 
ATOM   874  O  O   . ASP A  1 114 ? 28.16812 21.17021  -9.55513  1.000 14.38870 ? 114 ASP A O   1 
ATOM   875  C  CB  . ASP A  1 114 ? 30.27310 19.06307  -8.83264  1.000 14.47162 ? 114 ASP A CB  1 
ATOM   876  C  CG  . ASP A  1 114 ? 30.09480 19.04400  -10.33635 1.000 14.19174 ? 114 ASP A CG  1 
ATOM   877  O  OD1 . ASP A  1 114 ? 30.71355 19.88720  -11.01836 1.000 14.25950 ? 114 ASP A OD1 1 
ATOM   878  O  OD2 . ASP A  1 114 ? 29.34121 18.18298  -10.83639 1.000 17.02738 ? 114 ASP A OD2 1 
ATOM   879  N  N   . GLY A  1 115 ? 27.74547 20.81929  -7.37333  1.000 16.81925 ? 115 GLY A N   1 
ATOM   880  C  CA  . GLY A  1 115 ? 26.34481 21.16884  -7.49910  1.000 15.80239 ? 115 GLY A CA  1 
ATOM   881  C  C   . GLY A  1 115 ? 25.47860 19.99701  -7.91125  1.000 19.11062 ? 115 GLY A C   1 
ATOM   882  O  O   . GLY A  1 115 ? 24.79701 20.04968  -8.94038  1.000 18.63154 ? 115 GLY A O   1 
ATOM   883  N  N   . TYR A  1 116 ? 25.50465 18.93337  -7.11452  1.000 17.16507 ? 116 TYR A N   1 
ATOM   884  C  CA  . TYR A  1 116 ? 24.71178 17.75233  -7.41748  1.000 16.42462 ? 116 TYR A CA  1 
ATOM   885  C  C   . TYR A  1 116 ? 23.22635 18.11046  -7.41637  1.000 17.12713 ? 116 TYR A C   1 
ATOM   886  O  O   . TYR A  1 116 ? 22.78344 18.91435  -6.58663  1.000 18.91625 ? 116 TYR A O   1 
ATOM   887  C  CB  . TYR A  1 116 ? 24.99818 16.65001  -6.39559  1.000 15.85643 ? 116 TYR A CB  1 
ATOM   888  C  CG  . TYR A  1 116 ? 24.55235 15.27077  -6.82425  1.000 17.62883 ? 116 TYR A CG  1 
ATOM   889  C  CD1 . TYR A  1 116 ? 25.17019 14.62079  -7.88364  1.000 18.16925 ? 116 TYR A CD1 1 
ATOM   890  C  CD2 . TYR A  1 116 ? 23.52410 14.61279  -6.16210  1.000 15.17300 ? 116 TYR A CD2 1 
ATOM   891  C  CE1 . TYR A  1 116 ? 24.76781 13.36250  -8.28088  1.000 16.91736 ? 116 TYR A CE1 1 
ATOM   892  C  CE2 . TYR A  1 116 ? 23.11777 13.35017  -6.55065  1.000 17.32330 ? 116 TYR A CE2 1 
ATOM   893  C  CZ  . TYR A  1 116 ? 23.74523 12.72963  -7.61056  1.000 17.45897 ? 116 TYR A CZ  1 
ATOM   894  O  OH  . TYR A  1 116 ? 23.34995 11.47310  -8.00520  1.000 15.70986 ? 116 TYR A OH  1 
ATOM   895  N  N   . PRO A  1 117 ? 22.43392 17.55116  -8.33660  1.000 11.57863 ? 117 PRO A N   1 
ATOM   896  C  CA  . PRO A  1 117 ? 21.01373 17.93407  -8.40791  1.000 14.65408 ? 117 PRO A CA  1 
ATOM   897  C  C   . PRO A  1 117 ? 20.24062 17.66464  -7.13037  1.000 18.84639 ? 117 PRO A C   1 
ATOM   898  O  O   . PRO A  1 117 ? 19.32592 18.42984  -6.79976  1.000 16.66724 ? 117 PRO A O   1 
ATOM   899  C  CB  . PRO A  1 117 ? 20.48472 17.08971  -9.57608  1.000 12.23376 ? 117 PRO A CB  1 
ATOM   900  C  CG  . PRO A  1 117 ? 21.68502 16.80634  -10.40743 1.000 14.21428 ? 117 PRO A CG  1 
ATOM   901  C  CD  . PRO A  1 117 ? 22.81515 16.64771  -9.43414  1.000 14.63420 ? 117 PRO A CD  1 
ATOM   902  N  N   . GLU A  1 118 ? 20.57514 16.60527  -6.39932  1.000 18.55088 ? 118 GLU A N   1 
ATOM   903  C  CA  . GLU A  1 118 ? 19.89479 16.28451  -5.15424  1.000 18.59199 ? 118 GLU A CA  1 
ATOM   904  C  C   . GLU A  1 118 ? 20.59728 16.86422  -3.93232  1.000 22.00635 ? 118 GLU A C   1 
ATOM   905  O  O   . GLU A  1 118 ? 20.21481 16.54566  -2.80149  1.000 21.05330 ? 118 GLU A O   1 
ATOM   906  C  CB  . GLU A  1 118 ? 19.73826 14.76750  -5.01785  1.000 17.81912 ? 118 GLU A CB  1 
ATOM   907  C  CG  . GLU A  1 118 ? 18.57970 14.21672  -5.83793  1.000 23.73490 ? 118 GLU A CG  1 
ATOM   908  C  CD  . GLU A  1 118 ? 18.56415 12.70504  -5.90152  1.000 28.25576 ? 118 GLU A CD  1 
ATOM   909  O  OE1 . GLU A  1 118 ? 19.54784 12.07833  -5.45743  1.000 32.97490 ? 118 GLU A OE1 1 
ATOM   910  O  OE2 . GLU A  1 118 ? 17.56772 12.14294  -6.40182  1.000 30.24067 ? 118 GLU A OE2 1 
ATOM   911  N  N   . ALA A  1 119 ? 21.61406 17.70597  -4.13349  1.000 21.67129 ? 119 ALA A N   1 
ATOM   912  C  CA  . ALA A  1 119 ? 22.20823 18.49106  -3.05837  1.000 20.05931 ? 119 ALA A CA  1 
ATOM   913  C  C   . ALA A  1 119 ? 21.57275 19.87059  -2.93302  1.000 18.45504 ? 119 ALA A C   1 
ATOM   914  O  O   . ALA A  1 119 ? 22.22634 20.81628  -2.46919  1.000 16.96045 ? 119 ALA A O   1 
ATOM   915  C  CB  . ALA A  1 119 ? 23.71829 18.61452  -3.26612  1.000 17.98165 ? 119 ALA A CB  1 
ATOM   916  N  N   . TRP A  1 120 ? 20.31241 20.00743  -3.33852  1.000 17.21430 ? 120 TRP A N   1 
ATOM   917  C  CA  . TRP A  1 120 ? 19.63680 21.29417  -3.33405  1.000 17.18385 ? 120 TRP A CA  1 
ATOM   918  C  C   . TRP A  1 120 ? 19.32184 21.72968  -1.90488  1.000 19.25965 ? 120 TRP A C   1 
ATOM   919  O  O   . TRP A  1 120 ? 19.53533 21.00003  -0.93230  1.000 20.90879 ? 120 TRP A O   1 
ATOM   920  C  CB  . TRP A  1 120 ? 18.35990 21.22643  -4.16862  1.000 21.65251 ? 120 TRP A CB  1 
ATOM   921  C  CG  . TRP A  1 120 ? 17.43640 20.11308  -3.76673  1.000 18.96333 ? 120 TRP A CG  1 
ATOM   922  C  CD1 . TRP A  1 120 ? 17.32466 18.89098  -4.36004  1.000 19.54067 ? 120 TRP A CD1 1 
ATOM   923  C  CD2 . TRP A  1 120 ? 16.49922 20.11824  -2.68069  1.000 24.64377 ? 120 TRP A CD2 1 
ATOM   924  N  NE1 . TRP A  1 120 ? 16.37624 18.13543  -3.71535  1.000 25.04757 ? 120 TRP A NE1 1 
ATOM   925  C  CE2 . TRP A  1 120 ? 15.85495 18.86567  -2.68032  1.000 23.20589 ? 120 TRP A CE2 1 
ATOM   926  C  CE3 . TRP A  1 120 ? 16.14137 21.06046  -1.71033  1.000 26.04224 ? 120 TRP A CE3 1 
ATOM   927  C  CZ2 . TRP A  1 120 ? 14.87470 18.53070  -1.74896  1.000 21.41260 ? 120 TRP A CZ2 1 
ATOM   928  C  CZ3 . TRP A  1 120 ? 15.16828 20.72582  -0.78641  1.000 22.52750 ? 120 TRP A CZ3 1 
ATOM   929  C  CH2 . TRP A  1 120 ? 14.54609 19.47205  -0.81274  1.000 22.49788 ? 120 TRP A CH2 1 
ATOM   930  N  N   . TYR A  1 121 ? 18.78831 22.94199  -1.78836  1.000 23.71746 ? 121 TYR A N   1 
ATOM   931  C  CA  . TYR A  1 121 ? 18.42811 23.51401  -0.50084  1.000 21.24966 ? 121 TYR A CA  1 
ATOM   932  C  C   . TYR A  1 121 ? 17.45860 24.66101  -0.73662  1.000 18.77688 ? 121 TYR A C   1 
ATOM   933  O  O   . TYR A  1 121 ? 17.49367 25.31367  -1.78299  1.000 18.76357 ? 121 TYR A O   1 
ATOM   934  C  CB  . TYR A  1 121 ? 19.66381 24.00003  0.26550   1.000 16.98607 ? 121 TYR A CB  1 
ATOM   935  C  CG  . TYR A  1 121 ? 20.59049 24.86573  -0.55753  1.000 16.64297 ? 121 TYR A CG  1 
ATOM   936  C  CD1 . TYR A  1 121 ? 20.42754 26.24399  -0.60358  1.000 19.89283 ? 121 TYR A CD1 1 
ATOM   937  C  CD2 . TYR A  1 121 ? 21.62810 24.30391  -1.28989  1.000 16.52857 ? 121 TYR A CD2 1 
ATOM   938  C  CE1 . TYR A  1 121 ? 21.27185 27.03752  -1.35413  1.000 17.54134 ? 121 TYR A CE1 1 
ATOM   939  C  CE2 . TYR A  1 121 ? 22.47620 25.08847  -2.04417  1.000 14.59639 ? 121 TYR A CE2 1 
ATOM   940  C  CZ  . TYR A  1 121 ? 22.29431 26.45396  -2.07198  1.000 19.33690 ? 121 TYR A CZ  1 
ATOM   941  O  OH  . TYR A  1 121 ? 23.13816 27.23943  -2.82134  1.000 21.73190 ? 121 TYR A OH  1 
ATOM   942  N  N   . THR A  1 122 ? 16.59192 24.89358  0.24236   1.000 22.93731 ? 122 THR A N   1 
ATOM   943  C  CA  . THR A  1 122 ? 15.64064 25.99322  0.17695   1.000 24.29036 ? 122 THR A CA  1 
ATOM   944  C  C   . THR A  1 122 ? 16.27078 27.23441  0.81399   1.000 23.87082 ? 122 THR A C   1 
ATOM   945  O  O   . THR A  1 122 ? 17.48996 27.30463  0.99191   1.000 21.54187 ? 122 THR A O   1 
ATOM   946  C  CB  . THR A  1 122 ? 14.32271 25.58891  0.84556   1.000 26.91862 ? 122 THR A CB  1 
ATOM   947  O  OG1 . THR A  1 122 ? 14.57118 25.20402  2.20348   1.000 31.09359 ? 122 THR A OG1 1 
ATOM   948  C  CG2 . THR A  1 122 ? 13.67947 24.42877  0.09998   1.000 18.15307 ? 122 THR A CG2 1 
ATOM   949  N  N   . LYS A  1 123 ? 15.44980 28.22040  1.16822   1.000 24.04797 ? 123 LYS A N   1 
ATOM   950  C  CA  . LYS A  1 123 ? 15.96314 29.46484  1.72570   1.000 26.92056 ? 123 LYS A CA  1 
ATOM   951  C  C   . LYS A  1 123 ? 16.65976 29.21972  3.05901   1.000 27.54261 ? 123 LYS A C   1 
ATOM   952  O  O   . LYS A  1 123 ? 16.14709 28.49803  3.91961   1.000 30.18832 ? 123 LYS A O   1 
ATOM   953  C  CB  . LYS A  1 123 ? 14.82391 30.46757  1.90133   1.000 29.62011 ? 123 LYS A CB  1 
ATOM   954  C  CG  . LYS A  1 123 ? 15.23355 31.75707  2.58858   1.000 25.81372 ? 123 LYS A CG  1 
ATOM   955  C  CD  . LYS A  1 123 ? 14.03026 32.64800  2.83595   1.000 30.97792 ? 123 LYS A CD  1 
ATOM   956  C  CE  . LYS A  1 123 ? 14.40972 33.87053  3.65174   1.000 36.86837 ? 123 LYS A CE  1 
ATOM   957  N  NZ  . LYS A  1 123 ? 13.22815 34.72304  3.95507   1.000 46.91191 ? 123 LYS A NZ  1 
ATOM   958  N  N   . ASP A  1 124 ? 17.84004 29.82370  3.21744   1.000 27.86592 ? 124 ASP A N   1 
ATOM   959  C  CA  . ASP A  1 124 ? 18.63110 29.74551  4.44734   1.000 28.58487 ? 124 ASP A CA  1 
ATOM   960  C  C   . ASP A  1 124 ? 18.94580 28.30455  4.84080   1.000 27.26657 ? 124 ASP A C   1 
ATOM   961  O  O   . ASP A  1 124 ? 19.09856 27.99862  6.02589   1.000 30.33188 ? 124 ASP A O   1 
ATOM   962  C  CB  . ASP A  1 124 ? 17.93864 30.47243  5.60375   1.000 26.31373 ? 124 ASP A CB  1 
ATOM   963  C  CG  . ASP A  1 124 ? 17.83219 31.96653  5.37635   1.000 34.99830 ? 124 ASP A CG  1 
ATOM   964  O  OD1 . ASP A  1 124 ? 18.70886 32.53061  4.68887   1.000 41.37720 ? 124 ASP A OD1 1 
ATOM   965  O  OD2 . ASP A  1 124 ? 16.87003 32.57841  5.88667   1.000 34.45138 ? 124 ASP A OD2 1 
ATOM   966  N  N   . PHE A  1 125 ? 19.04296 27.41582  3.84817   1.000 27.20104 ? 125 PHE A N   1 
ATOM   967  C  CA  . PHE A  1 125 ? 19.40517 26.01138  4.05707   1.000 21.29987 ? 125 PHE A CA  1 
ATOM   968  C  C   . PHE A  1 125 ? 18.46134 25.30933  5.03022   1.000 23.49987 ? 125 PHE A C   1 
ATOM   969  O  O   . PHE A  1 125 ? 18.86074 24.37323  5.72611   1.000 26.08094 ? 125 PHE A O   1 
ATOM   970  C  CB  . PHE A  1 125 ? 20.85175 25.87206  4.54417   1.000 19.87358 ? 125 PHE A CB  1 
ATOM   971  C  CG  . PHE A  1 125 ? 21.86297 26.54115  3.65788   1.000 26.34692 ? 125 PHE A CG  1 
ATOM   972  C  CD1 . PHE A  1 125 ? 22.23863 25.96633  2.45421   1.000 25.97415 ? 125 PHE A CD1 1 
ATOM   973  C  CD2 . PHE A  1 125 ? 22.45176 27.73704  4.03661   1.000 20.26471 ? 125 PHE A CD2 1 
ATOM   974  C  CE1 . PHE A  1 125 ? 23.17467 26.57865  1.63819   1.000 22.36716 ? 125 PHE A CE1 1 
ATOM   975  C  CE2 . PHE A  1 125 ? 23.38853 28.35322  3.22688   1.000 19.30359 ? 125 PHE A CE2 1 
ATOM   976  C  CZ  . PHE A  1 125 ? 23.74996 27.77310  2.02596   1.000 23.57107 ? 125 PHE A CZ  1 
ATOM   977  N  N   . GLN A  1 126 ? 17.20083 25.74558  5.09111   1.000 23.70082 ? 126 GLN A N   1 
ATOM   978  C  CA  . GLN A  1 126 ? 16.28076 25.17074  6.06801   1.000 30.25027 ? 126 GLN A CA  1 
ATOM   979  C  C   . GLN A  1 126 ? 15.83856 23.76991  5.66205   1.000 32.22759 ? 126 GLN A C   1 
ATOM   980  O  O   . GLN A  1 126 ? 15.75822 22.87084  6.50720   1.000 34.45747 ? 126 GLN A O   1 
ATOM   981  C  CB  . GLN A  1 126 ? 15.07484 26.08666  6.26347   1.000 30.28480 ? 126 GLN A CB  1 
ATOM   982  C  CG  . GLN A  1 126 ? 15.03479 26.75149  7.63317   1.000 46.64301 ? 126 GLN A CG  1 
ATOM   983  C  CD  . GLN A  1 126 ? 16.21942 27.67009  7.87525   1.000 46.30727 ? 126 GLN A CD  1 
ATOM   984  O  OE1 . GLN A  1 126 ? 16.23438 28.81295  7.41880   1.000 55.42725 ? 126 GLN A OE1 1 
ATOM   985  N  NE2 . GLN A  1 126 ? 17.21928 27.17312  8.59693   1.000 37.42619 ? 126 GLN A NE2 1 
ATOM   986  N  N   . VAL A  1 127 ? 15.54431 23.56348  4.38185   1.000 28.19352 ? 127 VAL A N   1 
ATOM   987  C  CA  . VAL A  1 127 ? 15.23846 22.24432  3.84037   1.000 31.89393 ? 127 VAL A CA  1 
ATOM   988  C  C   . VAL A  1 127 ? 16.35404 21.86567  2.87849   1.000 31.44504 ? 127 VAL A C   1 
ATOM   989  O  O   . VAL A  1 127 ? 16.67679 22.63152  1.96265   1.000 29.95513 ? 127 VAL A O   1 
ATOM   990  C  CB  . VAL A  1 127 ? 13.86959 22.21801  3.13936   1.000 29.91336 ? 127 VAL A CB  1 
ATOM   991  C  CG1 . VAL A  1 127 ? 13.55736 20.81682  2.64640   1.000 18.21753 ? 127 VAL A CG1 1 
ATOM   992  C  CG2 . VAL A  1 127 ? 12.78216 22.71799  4.08022   1.000 21.03686 ? 127 VAL A CG2 1 
ATOM   993  N  N   . LYS A  1 128 ? 16.94327 20.69149  3.08807   1.000 28.60248 ? 128 LYS A N   1 
ATOM   994  C  CA  . LYS A  1 128 ? 18.10775 20.24667  2.33713   1.000 22.88564 ? 128 LYS A CA  1 
ATOM   995  C  C   . LYS A  1 128 ? 17.79395 18.95938  1.58809   1.000 25.80510 ? 128 LYS A C   1 
ATOM   996  O  O   . LYS A  1 128 ? 17.05531 18.10263  2.08493   1.000 27.79714 ? 128 LYS A O   1 
ATOM   997  C  CB  . LYS A  1 128 ? 19.30315 20.02227  3.26717   1.000 25.19303 ? 128 LYS A CB  1 
ATOM   998  C  CG  . LYS A  1 128 ? 19.65881 21.21973  4.13160   1.000 25.24227 ? 128 LYS A CG  1 
ATOM   999  C  CD  . LYS A  1 128 ? 20.67063 20.83257  5.19685   1.000 28.38526 ? 128 LYS A CD  1 
ATOM   1000 C  CE  . LYS A  1 128 ? 21.15268 22.04106  5.97838   1.000 31.93876 ? 128 LYS A CE  1 
ATOM   1001 N  NZ  . LYS A  1 128 ? 22.22184 21.67294  6.94691   1.000 35.55687 ? 128 LYS A NZ  1 
ATOM   1002 N  N   . GLY A  1 129 ? 18.36370 18.82733  0.39306   1.000 22.97640 ? 129 GLY A N   1 
ATOM   1003 C  CA  . GLY A  1 129 ? 18.24288 17.61457  -0.37774  1.000 18.52610 ? 129 GLY A CA  1 
ATOM   1004 C  C   . GLY A  1 129 ? 19.03884 16.48539  0.24346   1.000 26.11277 ? 129 GLY A C   1 
ATOM   1005 O  O   . GLY A  1 129 ? 19.90758 16.70399  1.09451   1.000 26.15200 ? 129 GLY A O   1 
ATOM   1006 N  N   . PRO A  1 130 ? 18.76228 15.24935  -0.17971  1.000 22.33617 ? 130 PRO A N   1 
ATOM   1007 C  CA  . PRO A  1 130 ? 19.41506 14.09147  0.45546   1.000 20.01061 ? 130 PRO A CA  1 
ATOM   1008 C  C   . PRO A  1 130 ? 20.92469 14.05611  0.28623   1.000 22.49830 ? 130 PRO A C   1 
ATOM   1009 O  O   . PRO A  1 130 ? 21.59427 13.32782  1.02923   1.000 23.76984 ? 130 PRO A O   1 
ATOM   1010 C  CB  . PRO A  1 130 ? 18.74814 12.89209  -0.23321  1.000 17.91129 ? 130 PRO A CB  1 
ATOM   1011 C  CG  . PRO A  1 130 ? 18.23575 13.43275  -1.52934  1.000 20.78821 ? 130 PRO A CG  1 
ATOM   1012 C  CD  . PRO A  1 130 ? 17.82384 14.84517  -1.23951  1.000 21.48711 ? 130 PRO A CD  1 
ATOM   1013 N  N   . PHE A  1 131 ? 21.48595 14.81318  -0.65559  1.000 22.12213 ? 131 PHE A N   1 
ATOM   1014 C  CA  . PHE A  1 131 ? 22.92390 14.81848  -0.89417  1.000 20.94900 ? 131 PHE A CA  1 
ATOM   1015 C  C   . PHE A  1 131 ? 23.59535 16.10940  -0.44253  1.000 23.96009 ? 131 PHE A C   1 
ATOM   1016 O  O   . PHE A  1 131 ? 24.76868 16.33011  -0.76277  1.000 26.54533 ? 131 PHE A O   1 
ATOM   1017 C  CB  . PHE A  1 131 ? 23.21378 14.56595  -2.37558  1.000 24.50422 ? 131 PHE A CB  1 
ATOM   1018 C  CG  . PHE A  1 131 ? 23.06587 13.12716  -2.78510  1.000 25.63258 ? 131 PHE A CG  1 
ATOM   1019 C  CD1 . PHE A  1 131 ? 21.81679 12.59214  -3.05412  1.000 25.16190 ? 131 PHE A CD1 1 
ATOM   1020 C  CD2 . PHE A  1 131 ? 24.17796 12.30972  -2.90194  1.000 24.48131 ? 131 PHE A CD2 1 
ATOM   1021 C  CE1 . PHE A  1 131 ? 21.68092 11.26724  -3.42893  1.000 24.64606 ? 131 PHE A CE1 1 
ATOM   1022 C  CE2 . PHE A  1 131 ? 24.04754 10.98602  -3.27785  1.000 24.74646 ? 131 PHE A CE2 1 
ATOM   1023 C  CZ  . PHE A  1 131 ? 22.79720 10.46471  -3.54196  1.000 21.09908 ? 131 PHE A CZ  1 
ATOM   1024 N  N   . PHE A  1 132 ? 22.88673 16.96536  0.28922   1.000 22.97098 ? 132 PHE A N   1 
ATOM   1025 C  CA  . PHE A  1 132 ? 23.48415 18.19739  0.78502   1.000 21.41773 ? 132 PHE A CA  1 
ATOM   1026 C  C   . PHE A  1 132 ? 24.54959 17.88656  1.82913   1.000 23.19488 ? 132 PHE A C   1 
ATOM   1027 O  O   . PHE A  1 132 ? 24.41788 16.94094  2.60929   1.000 31.72504 ? 132 PHE A O   1 
ATOM   1028 C  CB  . PHE A  1 132 ? 22.40864 19.10151  1.38454   1.000 23.84738 ? 132 PHE A CB  1 
ATOM   1029 C  CG  . PHE A  1 132 ? 22.92345 20.43403  1.84297   1.000 26.46171 ? 132 PHE A CG  1 
ATOM   1030 C  CD1 . PHE A  1 132 ? 23.40436 20.60242  3.13155   1.000 26.19192 ? 132 PHE A CD1 1 
ATOM   1031 C  CD2 . PHE A  1 132 ? 22.92137 21.52117  0.98642   1.000 22.99126 ? 132 PHE A CD2 1 
ATOM   1032 C  CE1 . PHE A  1 132 ? 23.87879 21.82743  3.55496   1.000 30.55553 ? 132 PHE A CE1 1 
ATOM   1033 C  CE2 . PHE A  1 132 ? 23.39357 22.74975  1.40449   1.000 25.15459 ? 132 PHE A CE2 1 
ATOM   1034 C  CZ  . PHE A  1 132 ? 23.87324 22.90324  2.69062   1.000 28.78253 ? 132 PHE A CZ  1 
ATOM   1035 N  N   . GLU A  1 133 ? 25.61403 18.69247  1.84432   1.000 27.93111 ? 133 GLU A N   1 
ATOM   1036 C  CA  . GLU A  1 133 ? 26.67040 18.48985  2.82925   1.000 31.63328 ? 133 GLU A CA  1 
ATOM   1037 C  C   . GLU A  1 133 ? 27.51801 19.73784  3.05143   1.000 28.58103 ? 133 GLU A C   1 
ATOM   1038 O  O   . GLU A  1 133 ? 28.28820 19.79974  4.01559   1.000 33.92144 ? 133 GLU A O   1 
ATOM   1039 C  CB  . GLU A  1 133 ? 27.56876 17.32284  2.41093   1.000 30.59998 ? 133 GLU A CB  1 
ATOM   1040 C  CG  . GLU A  1 133 ? 28.55977 17.65606  1.31097   1.000 27.58936 ? 133 GLU A CG  1 
ATOM   1041 C  CD  . GLU A  1 133 ? 29.30413 16.43248  0.81529   1.000 46.79765 ? 133 GLU A CD  1 
ATOM   1042 O  OE1 . GLU A  1 133 ? 28.67108 15.36322  0.68559   1.000 42.89345 ? 133 GLU A OE1 1 
ATOM   1043 O  OE2 . GLU A  1 133 ? 30.52313 16.53573  0.56491   1.000 54.09420 ? 133 GLU A OE2 1 
ATOM   1044 N  N   . ARG A  1 134 ? 27.39303 20.73465  2.17704   1.000 34.50248 ? 134 ARG A N   1 
ATOM   1045 C  CA  . ARG A  1 134 ? 28.22789 21.92533  2.25744   1.000 27.14043 ? 134 ARG A CA  1 
ATOM   1046 C  C   . ARG A  1 134 ? 27.41936 23.16977  1.92825   1.000 26.01682 ? 134 ARG A C   1 
ATOM   1047 O  O   . ARG A  1 134 ? 26.55831 23.14845  1.04455   1.000 27.83082 ? 134 ARG A O   1 
ATOM   1048 C  CB  . ARG A  1 134 ? 29.42709 21.83628  1.30403   1.000 22.65706 ? 134 ARG A CB  1 
ATOM   1049 C  CG  . ARG A  1 134 ? 30.52724 20.89719  1.75787   1.000 33.84317 ? 134 ARG A CG  1 
ATOM   1050 C  CD  . ARG A  1 134 ? 31.55187 20.69343  0.65430   1.000 38.92971 ? 134 ARG A CD  1 
ATOM   1051 N  NE  . ARG A  1 134 ? 32.27203 21.91926  0.33180   1.000 34.28243 ? 134 ARG A NE  1 
ATOM   1052 C  CZ  . ARG A  1 134 ? 33.54105 22.14541  0.64258   1.000 35.19851 ? 134 ARG A CZ  1 
ATOM   1053 N  NH1 . ARG A  1 134 ? 34.27023 21.23989  1.27363   1.000 34.76757 ? 134 ARG A NH1 1 
ATOM   1054 N  NH2 . ARG A  1 134 ? 34.09402 23.30713  0.30692   1.000 38.13909 ? 134 ARG A NH2 1 
ATOM   1055 N  N   . GLU A  1 135 ? 27.71219 24.25576  2.64426   1.000 29.44258 ? 135 GLU A N   1 
ATOM   1056 C  CA  . GLU A  1 135 ? 27.17537 25.57027  2.32242   1.000 22.21755 ? 135 GLU A CA  1 
ATOM   1057 C  C   . GLU A  1 135 ? 28.15461 26.43416  1.54309   1.000 17.31383 ? 135 GLU A C   1 
ATOM   1058 O  O   . GLU A  1 135 ? 27.72582 27.37600  0.86762   1.000 19.39821 ? 135 GLU A O   1 
ATOM   1059 C  CB  . GLU A  1 135 ? 26.77433 26.31473  3.60202   1.000 22.87490 ? 135 GLU A CB  1 
ATOM   1060 C  CG  . GLU A  1 135 ? 25.71024 25.62128  4.42943   1.000 21.76680 ? 135 GLU A CG  1 
ATOM   1061 C  CD  . GLU A  1 135 ? 25.33508 26.41735  5.66232   1.000 27.97931 ? 135 GLU A CD  1 
ATOM   1062 O  OE1 . GLU A  1 135 ? 25.95222 27.47833  5.89113   1.000 31.49092 ? 135 GLU A OE1 1 
ATOM   1063 O  OE2 . GLU A  1 135 ? 24.42450 25.98604  6.40121   1.000 33.60290 ? 135 GLU A OE2 1 
ATOM   1064 N  N   . VAL A  1 136 ? 29.44832 26.13754  1.62203   1.000 19.70980 ? 136 VAL A N   1 
ATOM   1065 C  CA  . VAL A  1 136 ? 30.49192 26.92479  0.97783   1.000 16.57513 ? 136 VAL A CA  1 
ATOM   1066 C  C   . VAL A  1 136 ? 31.21016 26.01536  -0.00787  1.000 17.29805 ? 136 VAL A C   1 
ATOM   1067 O  O   . VAL A  1 136 ? 31.91354 25.08093  0.39743   1.000 19.51544 ? 136 VAL A O   1 
ATOM   1068 C  CB  . VAL A  1 136 ? 31.47457 27.51888  1.99574   1.000 14.21262 ? 136 VAL A CB  1 
ATOM   1069 C  CG1 . VAL A  1 136 ? 32.59086 28.26547  1.28350   1.000 16.79492 ? 136 VAL A CG1 1 
ATOM   1070 C  CG2 . VAL A  1 136 ? 30.74515 28.43644  2.96259   1.000 15.59974 ? 136 VAL A CG2 1 
ATOM   1071 N  N   . TYR A  1 137 ? 31.03070 26.27968  -1.29818  1.000 21.74710 ? 137 TYR A N   1 
ATOM   1072 C  CA  . TYR A  1 137 ? 31.73319 25.53126  -2.32798  1.000 21.32911 ? 137 TYR A CA  1 
ATOM   1073 C  C   . TYR A  1 137 ? 33.15531 26.05316  -2.48229  1.000 19.22144 ? 137 TYR A C   1 
ATOM   1074 O  O   . TYR A  1 137 ? 33.44141 27.22367  -2.21787  1.000 17.04388 ? 137 TYR A O   1 
ATOM   1075 C  CB  . TYR A  1 137 ? 31.00266 25.62836  -3.66833  1.000 18.31634 ? 137 TYR A CB  1 
ATOM   1076 C  CG  . TYR A  1 137 ? 29.76455 24.76611  -3.78085  1.000 17.96342 ? 137 TYR A CG  1 
ATOM   1077 C  CD1 . TYR A  1 137 ? 29.31619 24.00574  -2.70753  1.000 16.85610 ? 137 TYR A CD1 1 
ATOM   1078 C  CD2 . TYR A  1 137 ? 29.05155 24.70301  -4.97037  1.000 17.12562 ? 137 TYR A CD2 1 
ATOM   1079 C  CE1 . TYR A  1 137 ? 28.18575 23.21575  -2.81470  1.000 15.38207 ? 137 TYR A CE1 1 
ATOM   1080 C  CE2 . TYR A  1 137 ? 27.92375 23.91625  -5.08735  1.000 17.31172 ? 137 TYR A CE2 1 
ATOM   1081 C  CZ  . TYR A  1 137 ? 27.49450 23.17448  -4.00872  1.000 18.84286 ? 137 TYR A CZ  1 
ATOM   1082 O  OH  . TYR A  1 137 ? 26.36950 22.39045  -4.12945  1.000 16.07783 ? 137 TYR A OH  1 
ATOM   1083 N  N   . GLU A  1 138 ? 34.05044 25.16875  -2.91639  1.000 17.65401 ? 138 GLU A N   1 
ATOM   1084 C  CA  . GLU A  1 138 ? 35.44306 25.51969  -3.15894  1.000 19.32556 ? 138 GLU A CA  1 
ATOM   1085 C  C   . GLU A  1 138 ? 35.85265 25.01854  -4.53496  1.000 19.89368 ? 138 GLU A C   1 
ATOM   1086 O  O   . GLU A  1 138 ? 35.70417 23.82978  -4.83703  1.000 15.32482 ? 138 GLU A O   1 
ATOM   1087 C  CB  . GLU A  1 138 ? 36.36309 24.93585  -2.08111  1.000 21.39325 ? 138 GLU A CB  1 
ATOM   1088 C  CG  . GLU A  1 138 ? 36.20491 25.58572  -0.71523  1.000 31.49533 ? 138 GLU A CG  1 
ATOM   1089 C  CD  . GLU A  1 138 ? 37.21260 25.07399  0.29657   1.000 46.62908 ? 138 GLU A CD  1 
ATOM   1090 O  OE1 . GLU A  1 138 ? 37.91888 24.09023  -0.01029  1.000 56.12574 ? 138 GLU A OE1 1 
ATOM   1091 O  OE2 . GLU A  1 138 ? 37.30131 25.65859  1.39753   1.000 43.84976 ? 138 GLU A OE2 1 
ATOM   1092 N  N   . TYR A  1 139 ? 36.36275 25.92584  -5.36352  1.000 13.28582 ? 139 TYR A N   1 
ATOM   1093 C  CA  . TYR A  1 139 ? 36.79796 25.58538  -6.71188  1.000 16.11687 ? 139 TYR A CA  1 
ATOM   1094 C  C   . TYR A  1 139 ? 38.31092 25.71393  -6.80236  1.000 16.44984 ? 139 TYR A C   1 
ATOM   1095 O  O   . TYR A  1 139 ? 38.83340 26.83916  -6.76719  1.000 19.62263 ? 139 TYR A O   1 
ATOM   1096 C  CB  . TYR A  1 139 ? 36.12097 26.49085  -7.74186  1.000 17.36788 ? 139 TYR A CB  1 
ATOM   1097 C  CG  . TYR A  1 139 ? 34.61225 26.49397  -7.65065  1.000 15.11314 ? 139 TYR A CG  1 
ATOM   1098 C  CD1 . TYR A  1 139 ? 33.85741 25.50804  -8.27061  1.000 15.38171 ? 139 TYR A CD1 1 
ATOM   1099 C  CD2 . TYR A  1 139 ? 33.94230 27.48383  -6.94416  1.000 16.65223 ? 139 TYR A CD2 1 
ATOM   1100 C  CE1 . TYR A  1 139 ? 32.47558 25.50782  -8.18896  1.000 15.88033 ? 139 TYR A CE1 1 
ATOM   1101 C  CE2 . TYR A  1 139 ? 32.56310 27.49168  -6.85669  1.000 14.67713 ? 139 TYR A CE2 1 
ATOM   1102 C  CZ  . TYR A  1 139 ? 31.83476 26.50190  -7.47997  1.000 12.21039 ? 139 TYR A CZ  1 
ATOM   1103 O  OH  . TYR A  1 139 ? 30.46111 26.50790  -7.39441  1.000 8.31406  ? 139 TYR A OH  1 
ATOM   1104 N  N   . PRO A  1 140 ? 39.05355 24.60884  -6.91287  1.000 17.21413 ? 140 PRO A N   1 
ATOM   1105 C  CA  . PRO A  1 140 ? 40.52127 24.71289  -6.96776  1.000 13.26063 ? 140 PRO A CA  1 
ATOM   1106 C  C   . PRO A  1 140 ? 41.03878 25.43245  -8.20111  1.000 19.42310 ? 140 PRO A C   1 
ATOM   1107 O  O   . PRO A  1 140 ? 42.16113 25.95445  -8.16144  1.000 22.25929 ? 140 PRO A O   1 
ATOM   1108 C  CB  . PRO A  1 140 ? 40.97974 23.24705  -6.94773  1.000 10.37241 ? 140 PRO A CB  1 
ATOM   1109 C  CG  . PRO A  1 140 ? 39.81721 22.48550  -6.38849  1.000 10.63748 ? 140 PRO A CG  1 
ATOM   1110 C  CD  . PRO A  1 140 ? 38.59862 23.21060  -6.86736  1.000 9.97808  ? 140 PRO A CD  1 
ATOM   1111 N  N   . ASN A  1 141 ? 40.26396 25.47069  -9.28913  1.000 17.46056 ? 141 ASN A N   1 
ATOM   1112 C  CA  . ASN A  1 141 ? 40.65771 26.15168  -10.52472 1.000 14.58310 ? 141 ASN A CA  1 
ATOM   1113 C  C   . ASN A  1 141 ? 41.99211 25.63026  -11.05333 1.000 17.79795 ? 141 ASN A C   1 
ATOM   1114 O  O   . ASN A  1 141 ? 42.84532 26.39740  -11.50391 1.000 21.97390 ? 141 ASN A O   1 
ATOM   1115 C  CB  . ASN A  1 141 ? 40.70779 27.66919  -10.33181 1.000 14.55624 ? 141 ASN A CB  1 
ATOM   1116 C  CG  . ASN A  1 141 ? 39.33560 28.27500  -10.11454 1.000 21.33277 ? 141 ASN A CG  1 
ATOM   1117 O  OD1 . ASN A  1 141 ? 38.35677 27.87008  -10.74287 1.000 21.18049 ? 141 ASN A OD1 1 
ATOM   1118 N  ND2 . ASN A  1 141 ? 39.25692 29.25107  -9.21894  1.000 21.39414 ? 141 ASN A ND2 1 
ATOM   1119 N  N   . GLU A  1 142 ? 42.17841 24.31539  -10.99429 1.000 20.88622 ? 142 GLU A N   1 
ATOM   1120 C  CA  . GLU A  1 142 ? 43.36913 23.68296  -11.56180 1.000 19.58643 ? 142 GLU A CA  1 
ATOM   1121 C  C   . GLU A  1 142 ? 43.12701 23.24697  -13.00341 1.000 17.99561 ? 142 GLU A C   1 
ATOM   1122 O  O   . GLU A  1 142 ? 43.36962 22.10211  -13.38198 1.000 26.81792 ? 142 GLU A O   1 
ATOM   1123 C  CB  . GLU A  1 142 ? 43.80489 22.50501  -10.69727 1.000 15.35905 ? 142 GLU A CB  1 
ATOM   1124 C  CG  . GLU A  1 142 ? 44.25098 22.88263  -9.29089  1.000 16.68020 ? 142 GLU A CG  1 
ATOM   1125 C  CD  . GLU A  1 142 ? 45.52465 23.71350  -9.26902  1.000 20.77219 ? 142 GLU A CD  1 
ATOM   1126 O  OE1 . GLU A  1 142 ? 46.24235 23.74913  -10.29072 1.000 27.22988 ? 142 GLU A OE1 1 
ATOM   1127 O  OE2 . GLU A  1 142 ? 45.81006 24.33303  -8.22279  1.000 25.19063 ? 142 GLU A OE2 1 
ATOM   1128 N  N   . GLN A  1 143 ? 42.63252 24.17462  -13.82002 1.000 16.11229 ? 143 GLN A N   1 
ATOM   1129 C  CA  . GLN A  1 143 ? 42.39456 23.92088  -15.23214 1.000 21.31374 ? 143 GLN A CA  1 
ATOM   1130 C  C   . GLN A  1 143 ? 42.84202 25.13206  -16.03648 1.000 18.12526 ? 143 GLN A C   1 
ATOM   1131 O  O   . GLN A  1 143 ? 43.02816 26.22666  -15.49918 1.000 17.74482 ? 143 GLN A O   1 
ATOM   1132 C  CB  . GLN A  1 143 ? 40.91941 23.60156  -15.51162 1.000 20.19653 ? 143 GLN A CB  1 
ATOM   1133 C  CG  . GLN A  1 143 ? 39.94815 24.64297  -14.99015 1.000 17.26647 ? 143 GLN A CG  1 
ATOM   1134 C  CD  . GLN A  1 143 ? 38.50058 24.21967  -15.14816 1.000 18.27435 ? 143 GLN A CD  1 
ATOM   1135 O  OE1 . GLN A  1 143 ? 37.76297 24.11798  -14.16832 1.000 21.76434 ? 143 GLN A OE1 1 
ATOM   1136 N  NE2 . GLN A  1 143 ? 38.08538 23.97357  -16.38557 1.000 13.32459 ? 143 GLN A NE2 1 
ATOM   1137 N  N   . ASP A  1 144 ? 43.01482 24.92038  -17.33853 1.000 18.70794 ? 144 ASP A N   1 
ATOM   1138 C  CA  . ASP A  1 144 ? 43.52518 25.96640  -18.20911 1.000 19.90401 ? 144 ASP A CA  1 
ATOM   1139 C  C   . ASP A  1 144 ? 42.46664 27.04571  -18.43827 1.000 18.64289 ? 144 ASP A C   1 
ATOM   1140 O  O   . ASP A  1 144 ? 41.28031 26.87241  -18.14388 1.000 20.60798 ? 144 ASP A O   1 
ATOM   1141 C  CB  . ASP A  1 144 ? 43.98785 25.37367  -19.53963 1.000 27.62967 ? 144 ASP A CB  1 
ATOM   1142 C  CG  . ASP A  1 144 ? 45.25049 24.53996  -19.39903 1.000 32.08314 ? 144 ASP A CG  1 
ATOM   1143 O  OD1 . ASP A  1 144 ? 45.84282 24.53388  -18.29845 1.000 22.39090 ? 144 ASP A OD1 1 
ATOM   1144 O  OD2 . ASP A  1 144 ? 45.65041 23.89090  -20.38908 1.000 30.88363 ? 144 ASP A OD2 1 
ATOM   1145 N  N   . ALA A  1 145 ? 42.91861 28.17740  -18.97616 1.000 17.18268 ? 145 ALA A N   1 
ATOM   1146 C  CA  . ALA A  1 145 ? 42.03886 29.32035  -19.18294 1.000 17.58842 ? 145 ALA A CA  1 
ATOM   1147 C  C   . ALA A  1 145 ? 40.94263 28.98780  -20.18401 1.000 17.26175 ? 145 ALA A C   1 
ATOM   1148 O  O   . ALA A  1 145 ? 41.21379 28.48665  -21.27886 1.000 23.61257 ? 145 ALA A O   1 
ATOM   1149 C  CB  . ALA A  1 145 ? 42.84043 30.52514  -19.67164 1.000 12.68411 ? 145 ALA A CB  1 
ATOM   1150 N  N   . THR A  1 146 ? 39.70256 29.28066  -19.80731 1.000 13.13458 ? 146 THR A N   1 
ATOM   1151 C  CA  . THR A  1 146 ? 38.55575 29.06287  -20.67756 1.000 15.42270 ? 146 THR A CA  1 
ATOM   1152 C  C   . THR A  1 146 ? 37.40438 29.91971  -20.16966 1.000 15.11122 ? 146 THR A C   1 
ATOM   1153 O  O   . THR A  1 146 ? 37.54762 30.68363  -19.21086 1.000 12.86072 ? 146 THR A O   1 
ATOM   1154 C  CB  . THR A  1 146 ? 38.16374 27.58437  -20.72822 1.000 13.36372 ? 146 THR A CB  1 
ATOM   1155 O  OG1 . THR A  1 146 ? 37.10399 27.40422  -21.67468 1.000 16.32464 ? 146 THR A OG1 1 
ATOM   1156 C  CG2 . THR A  1 146 ? 37.69800 27.11031  -19.35997 1.000 12.38936 ? 146 THR A CG2 1 
ATOM   1157 N  N   . ALA A  1 147 ? 36.25367 29.78096  -20.82292 1.000 12.74097 ? 147 ALA A N   1 
ATOM   1158 C  CA  . ALA A  1 147 ? 35.03445 30.48969  -20.45201 1.000 14.34773 ? 147 ALA A CA  1 
ATOM   1159 C  C   . ALA A  1 147 ? 34.04190 29.47567  -19.89781 1.000 16.93754 ? 147 ALA A C   1 
ATOM   1160 O  O   . ALA A  1 147 ? 33.55888 28.60555  -20.63047 1.000 15.68175 ? 147 ALA A O   1 
ATOM   1161 C  CB  . ALA A  1 147 ? 34.44736 31.23759  -21.64692 1.000 11.76539 ? 147 ALA A CB  1 
ATOM   1162 N  N   . LEU A  1 148 ? 33.74786 29.58396  -18.60853 1.000 13.71410 ? 148 LEU A N   1 
ATOM   1163 C  CA  . LEU A  1 148 ? 32.75409 28.75708  -17.94465 1.000 13.27592 ? 148 LEU A CA  1 
ATOM   1164 C  C   . LEU A  1 148 ? 31.52512 29.60248  -17.62860 1.000 14.16221 ? 148 LEU A C   1 
ATOM   1165 O  O   . LEU A  1 148 ? 31.45891 30.79227  -17.94973 1.000 13.98444 ? 148 LEU A O   1 
ATOM   1166 C  CB  . LEU A  1 148 ? 33.33235 28.13289  -16.67249 1.000 12.50051 ? 148 LEU A CB  1 
ATOM   1167 C  CG  . LEU A  1 148 ? 34.60817 27.30301  -16.80919 1.000 10.30765 ? 148 LEU A CG  1 
ATOM   1168 C  CD1 . LEU A  1 148 ? 35.01123 26.73649  -15.45938 1.000 10.16734 ? 148 LEU A CD1 1 
ATOM   1169 C  CD2 . LEU A  1 148 ? 34.42347 26.18868  -17.82869 1.000 13.31922 ? 148 LEU A CD2 1 
ATOM   1170 N  N   . TRP A  1 149 ? 30.54408 28.97264  -16.98781 1.000 11.78994 ? 149 TRP A N   1 
ATOM   1171 C  CA  . TRP A  1 149 ? 29.35607 29.68001  -16.53548 1.000 10.95304 ? 149 TRP A CA  1 
ATOM   1172 C  C   . TRP A  1 149 ? 28.67869 28.84591  -15.45951 1.000 13.90239 ? 149 TRP A C   1 
ATOM   1173 O  O   . TRP A  1 149 ? 28.79066 27.61755  -15.44743 1.000 14.90967 ? 149 TRP A O   1 
ATOM   1174 C  CB  . TRP A  1 149 ? 28.39237 29.97674  -17.69463 1.000 9.42873  ? 149 TRP A CB  1 
ATOM   1175 C  CG  . TRP A  1 149 ? 27.77403 28.77030  -18.33951 1.000 10.35188 ? 149 TRP A CG  1 
ATOM   1176 C  CD1 . TRP A  1 149 ? 28.42669 27.74044  -18.95275 1.000 11.64230 ? 149 TRP A CD1 1 
ATOM   1177 C  CD2 . TRP A  1 149 ? 26.37450 28.48783  -18.46409 1.000 10.02941 ? 149 TRP A CD2 1 
ATOM   1178 N  NE1 . TRP A  1 149 ? 27.52170 26.82712  -19.43768 1.000 9.93280  ? 149 TRP A NE1 1 
ATOM   1179 C  CE2 . TRP A  1 149 ? 26.25481 27.26356  -19.15178 1.000 10.77132 ? 149 TRP A CE2 1 
ATOM   1180 C  CE3 . TRP A  1 149 ? 25.21122 29.14870  -18.05576 1.000 12.98075 ? 149 TRP A CE3 1 
ATOM   1181 C  CZ2 . TRP A  1 149 ? 25.01906 26.68635  -19.43972 1.000 8.85985  ? 149 TRP A CZ2 1 
ATOM   1182 C  CZ3 . TRP A  1 149 ? 23.98545 28.57405  -18.34165 1.000 9.83038  ? 149 TRP A CZ3 1 
ATOM   1183 C  CH2 . TRP A  1 149 ? 23.89929 27.35537  -19.02767 1.000 11.46181 ? 149 TRP A CH2 1 
ATOM   1184 N  N   . TYR A  1 150 ? 27.98951 29.52771  -14.54849 1.000 13.52205 ? 150 TYR A N   1 
ATOM   1185 C  CA  . TYR A  1 150 ? 27.31233 28.88149  -13.43472 1.000 13.30965 ? 150 TYR A CA  1 
ATOM   1186 C  C   . TYR A  1 150 ? 25.80957 29.08513  -13.55752 1.000 14.68577 ? 150 TYR A C   1 
ATOM   1187 O  O   . TYR A  1 150 ? 25.34888 30.13325  -14.02177 1.000 11.88535 ? 150 TYR A O   1 
ATOM   1188 C  CB  . TYR A  1 150 ? 27.81708 29.41587  -12.08539 1.000 14.04911 ? 150 TYR A CB  1 
ATOM   1189 C  CG  . TYR A  1 150 ? 27.59956 30.89756  -11.86093 1.000 13.34730 ? 150 TYR A CG  1 
ATOM   1190 C  CD1 . TYR A  1 150 ? 28.47089 31.83828  -12.39476 1.000 13.42664 ? 150 TYR A CD1 1 
ATOM   1191 C  CD2 . TYR A  1 150 ? 26.53491 31.35372  -11.09502 1.000 13.68799 ? 150 TYR A CD2 1 
ATOM   1192 C  CE1 . TYR A  1 150 ? 28.27931 33.19213  -12.18322 1.000 12.88453 ? 150 TYR A CE1 1 
ATOM   1193 C  CE2 . TYR A  1 150 ? 26.33652 32.70356  -10.87943 1.000 17.74703 ? 150 TYR A CE2 1 
ATOM   1194 C  CZ  . TYR A  1 150 ? 27.21005 33.61873  -11.42651 1.000 15.66691 ? 150 TYR A CZ  1 
ATOM   1195 O  OH  . TYR A  1 150 ? 27.01236 34.96431  -11.21234 1.000 12.99119 ? 150 TYR A OH  1 
ATOM   1196 N  N   . HIS A  1 151 ? 25.05178 28.07301  -13.14511 1.000 12.41154 ? 151 HIS A N   1 
ATOM   1197 C  CA  . HIS A  1 151 ? 23.60033 28.10750  -13.24695 1.000 10.74964 ? 151 HIS A CA  1 
ATOM   1198 C  C   . HIS A  1 151 ? 23.02322 27.12059  -12.24384 1.000 12.83042 ? 151 HIS A C   1 
ATOM   1199 O  O   . HIS A  1 151 ? 23.74022 26.30044  -11.66531 1.000 11.14069 ? 151 HIS A O   1 
ATOM   1200 C  CB  . HIS A  1 151 ? 23.13133 27.78646  -14.67002 1.000 10.06984 ? 151 HIS A CB  1 
ATOM   1201 C  CG  . HIS A  1 151 ? 23.52870 26.42352  -15.14595 1.000 11.73575 ? 151 HIS A CG  1 
ATOM   1202 N  ND1 . HIS A  1 151 ? 22.90389 25.27244  -14.71681 1.000 12.04235 ? 151 HIS A ND1 1 
ATOM   1203 C  CD2 . HIS A  1 151 ? 24.48786 26.02803  -16.01583 1.000 10.71239 ? 151 HIS A CD2 1 
ATOM   1204 C  CE1 . HIS A  1 151 ? 23.46009 24.22730  -15.30249 1.000 9.45795  ? 151 HIS A CE1 1 
ATOM   1205 N  NE2 . HIS A  1 151 ? 24.42331 24.65856  -16.09623 1.000 7.97492  ? 151 HIS A NE2 1 
ATOM   1206 N  N   . ASP A  1 152 ? 21.71056 27.20877  -12.04804 1.000 10.64231 ? 152 ASP A N   1 
ATOM   1207 C  CA  . ASP A  1 152 ? 21.04059 26.32564  -11.10678 1.000 13.66284 ? 152 ASP A CA  1 
ATOM   1208 C  C   . ASP A  1 152 ? 20.98460 24.90255  -11.65164 1.000 14.11295 ? 152 ASP A C   1 
ATOM   1209 O  O   . ASP A  1 152 ? 20.98899 24.67344  -12.86428 1.000 12.65733 ? 152 ASP A O   1 
ATOM   1210 C  CB  . ASP A  1 152 ? 19.63171 26.83474  -10.80620 1.000 13.57340 ? 152 ASP A CB  1 
ATOM   1211 C  CG  . ASP A  1 152 ? 18.99159 26.11777  -9.63326  1.000 14.48958 ? 152 ASP A CG  1 
ATOM   1212 O  OD1 . ASP A  1 152 ? 18.57976 24.94994  -9.79492  1.000 15.01024 ? 152 ASP A OD1 1 
ATOM   1213 O  OD2 . ASP A  1 152 ? 18.91706 26.71848  -8.54132  1.000 18.11528 ? 152 ASP A OD2 1 
ATOM   1214 N  N   . HIS A  1 153 ? 20.93331 23.93519  -10.73165 1.000 12.49488 ? 153 HIS A N   1 
ATOM   1215 C  CA  . HIS A  1 153 ? 20.93812 22.53200  -11.12470 1.000 13.64266 ? 153 HIS A CA  1 
ATOM   1216 C  C   . HIS A  1 153 ? 20.00263 21.68462  -10.26627 1.000 13.95271 ? 153 HIS A C   1 
ATOM   1217 O  O   . HIS A  1 153 ? 20.15200 20.45708  -10.23543 1.000 13.43722 ? 153 HIS A O   1 
ATOM   1218 C  CB  . HIS A  1 153 ? 22.35935 21.96312  -11.05493 1.000 11.51230 ? 153 HIS A CB  1 
ATOM   1219 C  CG  . HIS A  1 153 ? 22.63391 20.89573  -12.06789 1.000 16.11591 ? 153 HIS A CG  1 
ATOM   1220 N  ND1 . HIS A  1 153 ? 21.82001 19.79549  -12.23057 1.000 14.61680 ? 153 HIS A ND1 1 
ATOM   1221 C  CD2 . HIS A  1 153 ? 23.63569 20.75908  -12.96883 1.000 14.58248 ? 153 HIS A CD2 1 
ATOM   1222 C  CE1 . HIS A  1 153 ? 22.30754 19.02812  -13.18928 1.000 18.06620 ? 153 HIS A CE1 1 
ATOM   1223 N  NE2 . HIS A  1 153 ? 23.40894 19.59007  -13.65364 1.000 13.92295 ? 153 HIS A NE2 1 
ATOM   1224 N  N   . ALA A  1 154 ? 19.05172 22.30254  -9.56681  1.000 11.63678 ? 154 ALA A N   1 
ATOM   1225 C  CA  . ALA A  1 154 ? 18.14463 21.55073  -8.70905  1.000 15.31044 ? 154 ALA A CA  1 
ATOM   1226 C  C   . ALA A  1 154 ? 17.32769 20.56248  -9.53127  1.000 14.36516 ? 154 ALA A C   1 
ATOM   1227 O  O   . ALA A  1 154 ? 16.88821 20.86701  -10.64364 1.000 16.96931 ? 154 ALA A O   1 
ATOM   1228 C  CB  . ALA A  1 154 ? 17.21823 22.50197  -7.95253  1.000 14.87633 ? 154 ALA A CB  1 
ATOM   1229 N  N   . MET A  1 155 ? 17.12470 19.37064  -8.97736  1.000 10.43814 ? 155 MET A N   1 
ATOM   1230 C  CA  . MET A  1 155 ? 16.48787 18.30631  -9.73853  1.000 21.60505 ? 155 MET A CA  1 
ATOM   1231 C  C   . MET A  1 155 ? 15.02584 18.63102  -10.02053 1.000 21.02290 ? 155 MET A C   1 
ATOM   1232 O  O   . MET A  1 155 ? 14.33798 19.24399  -9.19859  1.000 23.63783 ? 155 MET A O   1 
ATOM   1233 C  CB  . MET A  1 155 ? 16.59332 16.97203  -9.00031  1.000 18.55517 ? 155 MET A CB  1 
ATOM   1234 C  CG  . MET A  1 155 ? 16.11304 15.80317  -9.84731  1.000 18.39564 ? 155 MET A CG  1 
ATOM   1235 S  SD  . MET A  1 155 ? 16.63282 14.18602  -9.26766  1.000 37.99604 ? 155 MET A SD  1 
ATOM   1236 C  CE  . MET A  1 155 ? 15.38135 13.85100  -8.03135  1.000 32.23544 ? 155 MET A CE  1 
ATOM   1237 N  N   . ALA A  1 156 ? 14.57252 18.23924  -11.21561 1.000 18.84621 ? 156 ALA A N   1 
ATOM   1238 C  CA  . ALA A  1 156 ? 13.17904 18.30780  -11.64806 1.000 21.49414 ? 156 ALA A CA  1 
ATOM   1239 C  C   . ALA A  1 156 ? 12.70720 19.73024  -11.93006 1.000 14.48275 ? 156 ALA A C   1 
ATOM   1240 O  O   . ALA A  1 156 ? 11.62019 19.91927  -12.48403 1.000 17.54399 ? 156 ALA A O   1 
ATOM   1241 C  CB  . ALA A  1 156 ? 12.25828 17.64616  -10.61659 1.000 22.80573 ? 156 ALA A CB  1 
ATOM   1242 N  N   . ILE A  1 157 ? 13.50171 20.73690  -11.56703 1.000 17.37214 ? 157 ILE A N   1 
ATOM   1243 C  CA  . ILE A  1 157 ? 13.10973 22.12466  -11.79809 1.000 18.51687 ? 157 ILE A CA  1 
ATOM   1244 C  C   . ILE A  1 157 ? 14.27733 22.92434  -12.36196 1.000 15.51528 ? 157 ILE A C   1 
ATOM   1245 O  O   . ILE A  1 157 ? 14.29085 24.15817  -12.28270 1.000 17.05713 ? 157 ILE A O   1 
ATOM   1246 C  CB  . ILE A  1 157 ? 12.57792 22.78304  -10.51072 1.000 16.02504 ? 157 ILE A CB  1 
ATOM   1247 C  CG1 . ILE A  1 157 ? 13.62794 22.71873  -9.40027  1.000 13.01416 ? 157 ILE A CG1 1 
ATOM   1248 C  CG2 . ILE A  1 157 ? 11.26943 22.13700  -10.07225 1.000 14.10458 ? 157 ILE A CG2 1 
ATOM   1249 C  CD1 . ILE A  1 157 ? 13.27207 23.54022  -8.18370  1.000 14.72258 ? 157 ILE A CD1 1 
ATOM   1250 N  N   . THR A  1 158 ? 15.26416 22.23222  -12.93666 1.000 14.71234 ? 158 THR A N   1 
ATOM   1251 C  CA  . THR A  1 158 ? 16.38971 22.93320  -13.54692 1.000 15.65305 ? 158 THR A CA  1 
ATOM   1252 C  C   . THR A  1 158 ? 15.94147 23.77695  -14.73510 1.000 20.28301 ? 158 THR A C   1 
ATOM   1253 O  O   . THR A  1 158 ? 16.48517 24.86424  -14.96637 1.000 15.48201 ? 158 THR A O   1 
ATOM   1254 C  CB  . THR A  1 158 ? 17.46707 21.93108  -13.97043 1.000 14.99720 ? 158 THR A CB  1 
ATOM   1255 O  OG1 . THR A  1 158 ? 17.93023 21.21469  -12.81941 1.000 12.42738 ? 158 THR A OG1 1 
ATOM   1256 C  CG2 . THR A  1 158 ? 18.64874 22.64345  -14.61728 1.000 12.34967 ? 158 THR A CG2 1 
ATOM   1257 N  N   . ARG A  1 159 ? 14.94214 23.30584  -15.48636 1.000 15.86984 ? 159 ARG A N   1 
ATOM   1258 C  CA  . ARG A  1 159 ? 14.42852 24.08808  -16.60550 1.000 15.02501 ? 159 ARG A CA  1 
ATOM   1259 C  C   . ARG A  1 159 ? 13.78081 25.38218  -16.13323 1.000 16.57348 ? 159 ARG A C   1 
ATOM   1260 O  O   . ARG A  1 159 ? 13.79121 26.38151  -16.85985 1.000 14.97717 ? 159 ARG A O   1 
ATOM   1261 C  CB  . ARG A  1 159 ? 13.42864 23.25805  -17.41451 1.000 19.82343 ? 159 ARG A CB  1 
ATOM   1262 C  CG  . ARG A  1 159 ? 12.09875 23.02205  -16.71223 1.000 17.94391 ? 159 ARG A CG  1 
ATOM   1263 C  CD  . ARG A  1 159 ? 11.31565 21.88500  -17.34531 1.000 18.66274 ? 159 ARG A CD  1 
ATOM   1264 N  NE  . ARG A  1 159 ? 9.99438  21.74484  -16.74495 1.000 17.10164 ? 159 ARG A NE  1 
ATOM   1265 C  CZ  . ARG A  1 159 ? 9.75481  21.12434  -15.59781 1.000 17.31713 ? 159 ARG A CZ  1 
ATOM   1266 N  NH1 . ARG A  1 159 ? 10.72908 20.56980  -14.89500 1.000 20.36009 ? 159 ARG A NH1 1 
ATOM   1267 N  NH2 . ARG A  1 159 ? 8.50696  21.06160  -15.14247 1.000 15.48928 ? 159 ARG A NH2 1 
ATOM   1268 N  N   . LEU A  1 160 ? 13.22617 25.39021  -14.92014 1.000 18.59366 ? 160 LEU A N   1 
ATOM   1269 C  CA  . LEU A  1 160 ? 12.53241 26.57369  -14.42492 1.000 23.09977 ? 160 LEU A CA  1 
ATOM   1270 C  C   . LEU A  1 160 ? 13.50528 27.57437  -13.81285 1.000 20.34655 ? 160 LEU A C   1 
ATOM   1271 O  O   . LEU A  1 160 ? 13.45233 28.77019  -14.12065 1.000 16.78218 ? 160 LEU A O   1 
ATOM   1272 C  CB  . LEU A  1 160 ? 11.46875 26.16506  -13.40408 1.000 18.33190 ? 160 LEU A CB  1 
ATOM   1273 C  CG  . LEU A  1 160 ? 10.44345 25.14341  -13.89822 1.000 17.63648 ? 160 LEU A CG  1 
ATOM   1274 C  CD1 . LEU A  1 160 ? 9.48002  24.76769  -12.78788 1.000 12.05561 ? 160 LEU A CD1 1 
ATOM   1275 C  CD2 . LEU A  1 160 ? 9.69224  25.68123  -15.10555 1.000 19.00253 ? 160 LEU A CD2 1 
ATOM   1276 N  N   . ASN A  1 161 ? 14.40329 27.09918  -12.94584 1.000 19.33974 ? 161 ASN A N   1 
ATOM   1277 C  CA  . ASN A  1 161 ? 15.31692 28.00196  -12.25282 1.000 15.38688 ? 161 ASN A CA  1 
ATOM   1278 C  C   . ASN A  1 161 ? 16.27606 28.68005  -13.22379 1.000 14.10247 ? 161 ASN A C   1 
ATOM   1279 O  O   . ASN A  1 161 ? 16.58101 29.86896  -13.07644 1.000 17.09078 ? 161 ASN A O   1 
ATOM   1280 C  CB  . ASN A  1 161 ? 16.08654 27.23696  -11.17732 1.000 20.55142 ? 161 ASN A CB  1 
ATOM   1281 C  CG  . ASN A  1 161 ? 15.23770 26.93398  -9.95893  1.000 16.46716 ? 161 ASN A CG  1 
ATOM   1282 O  OD1 . ASN A  1 161 ? 14.06504 27.30290  -9.89767  1.000 16.61720 ? 161 ASN A OD1 1 
ATOM   1283 N  ND2 . ASN A  1 161 ? 15.82716 26.25721  -8.98098  1.000 18.32205 ? 161 ASN A ND2 1 
ATOM   1284 N  N   . VAL A  1 162 ? 16.76589 27.94178  -14.22075 1.000 13.76983 ? 162 VAL A N   1 
ATOM   1285 C  CA  . VAL A  1 162 ? 17.64319 28.54335  -15.21971 1.000 12.87272 ? 162 VAL A CA  1 
ATOM   1286 C  C   . VAL A  1 162 ? 16.87148 29.54142  -16.07338 1.000 14.63490 ? 162 VAL A C   1 
ATOM   1287 O  O   . VAL A  1 162 ? 17.35213 30.64715  -16.35053 1.000 14.75347 ? 162 VAL A O   1 
ATOM   1288 C  CB  . VAL A  1 162 ? 18.30011 27.44813  -16.07868 1.000 13.33841 ? 162 VAL A CB  1 
ATOM   1289 C  CG1 . VAL A  1 162 ? 19.04278 28.06219  -17.25211 1.000 7.88399  ? 162 VAL A CG1 1 
ATOM   1290 C  CG2 . VAL A  1 162 ? 19.23682 26.59768  -15.23169 1.000 13.80652 ? 162 VAL A CG2 1 
ATOM   1291 N  N   . TYR A  1 163 ? 15.66174 29.17094  -16.49850 1.000 15.70580 ? 163 TYR A N   1 
ATOM   1292 C  CA  . TYR A  1 163 ? 14.82967 30.08736  -17.26975 1.000 15.08173 ? 163 TYR A CA  1 
ATOM   1293 C  C   . TYR A  1 163 ? 14.42401 31.30221  -16.44663 1.000 15.31735 ? 163 TYR A C   1 
ATOM   1294 O  O   . TYR A  1 163 ? 14.24805 32.39323  -17.00041 1.000 15.90821 ? 163 TYR A O   1 
ATOM   1295 C  CB  . TYR A  1 163 ? 13.59487 29.34958  -17.78652 1.000 15.30259 ? 163 TYR A CB  1 
ATOM   1296 C  CG  . TYR A  1 163 ? 12.70850 30.15630  -18.70304 1.000 19.00608 ? 163 TYR A CG  1 
ATOM   1297 C  CD1 . TYR A  1 163 ? 13.11186 30.46316  -19.99502 1.000 21.91611 ? 163 TYR A CD1 1 
ATOM   1298 C  CD2 . TYR A  1 163 ? 11.45596 30.59052  -18.28577 1.000 15.21712 ? 163 TYR A CD2 1 
ATOM   1299 C  CE1 . TYR A  1 163 ? 12.30103 31.19434  -20.84020 1.000 21.11781 ? 163 TYR A CE1 1 
ATOM   1300 C  CE2 . TYR A  1 163 ? 10.63737 31.32078  -19.12594 1.000 14.26973 ? 163 TYR A CE2 1 
ATOM   1301 C  CZ  . TYR A  1 163 ? 11.06508 31.61935  -20.40228 1.000 18.36617 ? 163 TYR A CZ  1 
ATOM   1302 O  OH  . TYR A  1 163 ? 10.25611 32.34716  -21.24526 1.000 22.83373 ? 163 TYR A OH  1 
ATOM   1303 N  N   . ALA A  1 164 ? 14.28175 31.13788  -15.12831 1.000 15.16412 ? 164 ALA A N   1 
ATOM   1304 C  CA  . ALA A  1 164 ? 13.93651 32.24977  -14.25113 1.000 16.47892 ? 164 ALA A CA  1 
ATOM   1305 C  C   . ALA A  1 164 ? 15.03078 33.30578  -14.17081 1.000 15.24444 ? 164 ALA A C   1 
ATOM   1306 O  O   . ALA A  1 164 ? 14.76716 34.40302  -13.66816 1.000 15.88474 ? 164 ALA A O   1 
ATOM   1307 C  CB  . ALA A  1 164 ? 13.61820 31.73471  -12.84728 1.000 17.49249 ? 164 ALA A CB  1 
ATOM   1308 N  N   . GLY A  1 165 ? 16.24097 33.00566  -14.63866 1.000 17.98866 ? 165 GLY A N   1 
ATOM   1309 C  CA  . GLY A  1 165 ? 17.29765 33.99679  -14.69796 1.000 18.32296 ? 165 GLY A CA  1 
ATOM   1310 C  C   . GLY A  1 165 ? 18.53928 33.64103  -13.90629 1.000 16.08983 ? 165 GLY A C   1 
ATOM   1311 O  O   . GLY A  1 165 ? 19.44294 34.46944  -13.75865 1.000 13.44897 ? 165 GLY A O   1 
ATOM   1312 N  N   . LEU A  1 166 ? 18.60043 32.41287  -13.39240 1.000 13.68952 ? 166 LEU A N   1 
ATOM   1313 C  CA  . LEU A  1 166 ? 19.73013 31.97436  -12.57034 1.000 13.53577 ? 166 LEU A CA  1 
ATOM   1314 C  C   . LEU A  1 166 ? 20.85116 31.44240  -13.46568 1.000 12.37104 ? 166 LEU A C   1 
ATOM   1315 O  O   . LEU A  1 166 ? 21.13290 30.24549  -13.53780 1.000 8.86950  ? 166 LEU A O   1 
ATOM   1316 C  CB  . LEU A  1 166 ? 19.27471 30.93440  -11.55579 1.000 14.35202 ? 166 LEU A CB  1 
ATOM   1317 C  CG  . LEU A  1 166 ? 18.47403 31.48433  -10.37521 1.000 15.45452 ? 166 LEU A CG  1 
ATOM   1318 C  CD1 . LEU A  1 166 ? 17.75623 30.36634  -9.63587  1.000 14.48370 ? 166 LEU A CD1 1 
ATOM   1319 C  CD2 . LEU A  1 166 ? 19.39259 32.24825  -9.43388  1.000 14.59372 ? 166 LEU A CD2 1 
ATOM   1320 N  N   . VAL A  1 167 ? 21.49320 32.37789  -14.16543 1.000 14.51489 ? 167 VAL A N   1 
ATOM   1321 C  CA  . VAL A  1 167 ? 22.65910 32.09272  -14.99182 1.000 10.10352 ? 167 VAL A CA  1 
ATOM   1322 C  C   . VAL A  1 167 ? 23.67114 33.21228  -14.79766 1.000 15.27487 ? 167 VAL A C   1 
ATOM   1323 O  O   . VAL A  1 167 ? 23.31299 34.35554  -14.49965 1.000 18.82408 ? 167 VAL A O   1 
ATOM   1324 C  CB  . VAL A  1 167 ? 22.30662 31.94492  -16.49030 1.000 10.74514 ? 167 VAL A CB  1 
ATOM   1325 C  CG1 . VAL A  1 167 ? 21.40667 30.74309  -16.71763 1.000 14.34125 ? 167 VAL A CG1 1 
ATOM   1326 C  CG2 . VAL A  1 167 ? 21.65885 33.21469  -17.01697 1.000 14.02302 ? 167 VAL A CG2 1 
ATOM   1327 N  N   . GLY A  1 168 ? 24.94383 32.87553  -14.96837 1.000 11.13398 ? 168 GLY A N   1 
ATOM   1328 C  CA  . GLY A  1 168 ? 26.00396 33.85321  -14.82629 1.000 12.93824 ? 168 GLY A CA  1 
ATOM   1329 C  C   . GLY A  1 168 ? 27.28954 33.32289  -15.41338 1.000 13.92380 ? 168 GLY A C   1 
ATOM   1330 O  O   . GLY A  1 168 ? 27.44921 32.11495  -15.61490 1.000 14.64376 ? 168 GLY A O   1 
ATOM   1331 N  N   . LEU A  1 169 ? 28.21123 34.24439  -15.67379 1.000 10.43400 ? 169 LEU A N   1 
ATOM   1332 C  CA  . LEU A  1 169 ? 29.46673 33.92812  -16.33689 1.000 11.88765 ? 169 LEU A CA  1 
ATOM   1333 C  C   . LEU A  1 169 ? 30.58695 33.70274  -15.32606 1.000 17.26513 ? 169 LEU A C   1 
ATOM   1334 O  O   . LEU A  1 169 ? 30.51415 34.12494  -14.16988 1.000 18.52167 ? 169 LEU A O   1 
ATOM   1335 C  CB  . LEU A  1 169 ? 29.85389 35.04319  -17.30966 1.000 16.99419 ? 169 LEU A CB  1 
ATOM   1336 C  CG  . LEU A  1 169 ? 28.85749 35.28276  -18.44440 1.000 17.37060 ? 169 LEU A CG  1 
ATOM   1337 C  CD1 . LEU A  1 169 ? 29.28320 36.47669  -19.27388 1.000 11.40837 ? 169 LEU A CD1 1 
ATOM   1338 C  CD2 . LEU A  1 169 ? 28.72021 34.04115  -19.31134 1.000 8.93246  ? 169 LEU A CD2 1 
ATOM   1339 N  N   . TYR A  1 170 ? 31.64156 33.03552  -15.79422 1.000 15.39326 ? 170 TYR A N   1 
ATOM   1340 C  CA  . TYR A  1 170 ? 32.75746 32.63512  -14.93931 1.000 14.03829 ? 170 TYR A CA  1 
ATOM   1341 C  C   . TYR A  1 170 ? 33.95189 32.39688  -15.85319 1.000 13.36769 ? 170 TYR A C   1 
ATOM   1342 O  O   . TYR A  1 170 ? 33.95576 31.42744  -16.61728 1.000 13.03185 ? 170 TYR A O   1 
ATOM   1343 C  CB  . TYR A  1 170 ? 32.39748 31.37992  -14.14641 1.000 13.53178 ? 170 TYR A CB  1 
ATOM   1344 C  CG  . TYR A  1 170 ? 33.44593 30.87709  -13.16883 1.000 11.94393 ? 170 TYR A CG  1 
ATOM   1345 C  CD1 . TYR A  1 170 ? 34.59195 30.22781  -13.61319 1.000 10.93862 ? 170 TYR A CD1 1 
ATOM   1346 C  CD2 . TYR A  1 170 ? 33.26081 31.00615  -11.79813 1.000 10.13575 ? 170 TYR A CD2 1 
ATOM   1347 C  CE1 . TYR A  1 170 ? 35.53835 29.75456  -12.72284 1.000 13.28257 ? 170 TYR A CE1 1 
ATOM   1348 C  CE2 . TYR A  1 170 ? 34.20104 30.53640  -10.89931 1.000 10.19835 ? 170 TYR A CE2 1 
ATOM   1349 C  CZ  . TYR A  1 170 ? 35.33736 29.90930  -11.36654 1.000 17.48183 ? 170 TYR A CZ  1 
ATOM   1350 O  OH  . TYR A  1 170 ? 36.27600 29.43522  -10.47577 1.000 13.29599 ? 170 TYR A OH  1 
ATOM   1351 N  N   . PHE A  1 171 ? 34.95251 33.27016  -15.78020 1.000 13.29053 ? 171 PHE A N   1 
ATOM   1352 C  CA  . PHE A  1 171 ? 36.12056 33.19522  -16.64704 1.000 12.19479 ? 171 PHE A CA  1 
ATOM   1353 C  C   . PHE A  1 171 ? 37.34819 32.75895  -15.85921 1.000 14.16659 ? 171 PHE A C   1 
ATOM   1354 O  O   . PHE A  1 171 ? 37.54517 33.17367  -14.71193 1.000 11.61258 ? 171 PHE A O   1 
ATOM   1355 C  CB  . PHE A  1 171 ? 36.39692 34.54204  -17.32039 1.000 14.85008 ? 171 PHE A CB  1 
ATOM   1356 C  CG  . PHE A  1 171 ? 35.33953 34.96086  -18.29939 1.000 14.49866 ? 171 PHE A CG  1 
ATOM   1357 C  CD1 . PHE A  1 171 ? 35.34403 34.47326  -19.59579 1.000 14.76374 ? 171 PHE A CD1 1 
ATOM   1358 C  CD2 . PHE A  1 171 ? 34.34667 35.84820  -17.92652 1.000 14.53075 ? 171 PHE A CD2 1 
ATOM   1359 C  CE1 . PHE A  1 171 ? 34.37478 34.85979  -20.49876 1.000 13.13933 ? 171 PHE A CE1 1 
ATOM   1360 C  CE2 . PHE A  1 171 ? 33.37346 36.23819  -18.82548 1.000 19.01375 ? 171 PHE A CE2 1 
ATOM   1361 C  CZ  . PHE A  1 171 ? 33.38811 35.74341  -20.11279 1.000 16.68375 ? 171 PHE A CZ  1 
ATOM   1362 N  N   . ILE A  1 172 ? 38.16816 31.91923  -16.48623 1.000 10.22490 ? 172 ILE A N   1 
ATOM   1363 C  CA  . ILE A  1 172 ? 39.45397 31.49640  -15.94647 1.000 13.18621 ? 172 ILE A CA  1 
ATOM   1364 C  C   . ILE A  1 172 ? 40.54398 32.01944  -16.87072 1.000 16.02485 ? 172 ILE A C   1 
ATOM   1365 O  O   . ILE A  1 172 ? 40.40378 31.96836  -18.09756 1.000 15.90744 ? 172 ILE A O   1 
ATOM   1366 C  CB  . ILE A  1 172 ? 39.53785 29.96188  -15.80669 1.000 11.48628 ? 172 ILE A CB  1 
ATOM   1367 C  CG1 . ILE A  1 172 ? 38.40587 29.44554  -14.91719 1.000 10.01171 ? 172 ILE A CG1 1 
ATOM   1368 C  CG2 . ILE A  1 172 ? 40.89032 29.54023  -15.25314 1.000 10.27866 ? 172 ILE A CG2 1 
ATOM   1369 C  CD1 . ILE A  1 172 ? 38.40740 27.94405  -14.73831 1.000 10.25228 ? 172 ILE A CD1 1 
ATOM   1370 N  N   . ARG A  1 173 ? 41.62315 32.53076  -16.28329 1.000 19.87442 ? 173 ARG A N   1 
ATOM   1371 C  CA  . ARG A  1 173 ? 42.71525 33.12551  -17.03804 1.000 23.66956 ? 173 ARG A CA  1 
ATOM   1372 C  C   . ARG A  1 173 ? 44.00187 32.34173  -16.81498 1.000 22.32992 ? 173 ARG A C   1 
ATOM   1373 O  O   . ARG A  1 173 ? 44.20904 31.74203  -15.75562 1.000 24.81163 ? 173 ARG A O   1 
ATOM   1374 C  CB  . ARG A  1 173 ? 42.93131 34.59107  -16.64290 1.000 24.09703 ? 173 ARG A CB  1 
ATOM   1375 C  CG  . ARG A  1 173 ? 41.66987 35.44142  -16.65753 1.000 23.35358 ? 173 ARG A CG  1 
ATOM   1376 C  CD  . ARG A  1 173 ? 41.11356 35.60330  -18.06053 1.000 17.97174 ? 173 ARG A CD  1 
ATOM   1377 N  NE  . ARG A  1 173 ? 39.95120 36.48420  -18.08666 1.000 17.56291 ? 173 ARG A NE  1 
ATOM   1378 C  CZ  . ARG A  1 173 ? 39.31590 36.85277  -19.19106 1.000 19.81607 ? 173 ARG A CZ  1 
ATOM   1379 N  NH1 . ARG A  1 173 ? 39.70751 36.43754  -20.38520 1.000 15.18519 ? 173 ARG A NH1 1 
ATOM   1380 N  NH2 . ARG A  1 173 ? 38.26268 37.65994  -19.09557 1.000 18.01419 ? 173 ARG A NH2 1 
ATOM   1381 N  N   . ASP A  1 174 ? 44.86277 32.35623  -17.83048 1.000 26.20173 ? 174 ASP A N   1 
ATOM   1382 C  CA  . ASP A  1 174 ? 46.16314 31.70759  -17.79576 1.000 21.54807 ? 174 ASP A CA  1 
ATOM   1383 C  C   . ASP A  1 174 ? 47.25291 32.71949  -18.10920 1.000 25.66326 ? 174 ASP A C   1 
ATOM   1384 O  O   . ASP A  1 174 ? 46.99347 33.79908  -18.64689 1.000 28.57666 ? 174 ASP A O   1 
ATOM   1385 C  CB  . ASP A  1 174 ? 46.25773 30.55809  -18.80888 1.000 20.02695 ? 174 ASP A CB  1 
ATOM   1386 C  CG  . ASP A  1 174 ? 45.77768 29.24708  -18.24994 1.000 24.74937 ? 174 ASP A CG  1 
ATOM   1387 O  OD1 . ASP A  1 174 ? 45.68267 29.13367  -17.01332 1.000 36.88092 ? 174 ASP A OD1 1 
ATOM   1388 O  OD2 . ASP A  1 174 ? 45.51341 28.32462  -19.04817 1.000 31.37221 ? 174 ASP A OD2 1 
ATOM   1389 N  N   . ARG A  1 175 ? 48.48786 32.35153  -17.76813 1.000 22.79724 ? 175 ARG A N   1 
ATOM   1390 C  CA  . ARG A  1 175 ? 49.62890 33.08959  -18.29155 1.000 28.38346 ? 175 ARG A CA  1 
ATOM   1391 C  C   . ARG A  1 175 ? 49.81821 32.81385  -19.77746 1.000 25.02700 ? 175 ARG A C   1 
ATOM   1392 O  O   . ARG A  1 175 ? 50.29999 33.68175  -20.51403 1.000 24.79126 ? 175 ARG A O   1 
ATOM   1393 C  CB  . ARG A  1 175 ? 50.88703 32.73967  -17.49577 1.000 27.34633 ? 175 ARG A CB  1 
ATOM   1394 C  CG  . ARG A  1 175 ? 50.81982 33.22624  -16.05252 1.000 40.68703 ? 175 ARG A CG  1 
ATOM   1395 C  CD  . ARG A  1 175 ? 51.98571 32.74360  -15.19605 1.000 37.11598 ? 175 ARG A CD  1 
ATOM   1396 N  NE  . ARG A  1 175 ? 51.87112 33.24862  -13.83147 1.000 50.59974 ? 175 ARG A NE  1 
ATOM   1397 C  CZ  . ARG A  1 175 ? 51.68530 32.49443  -12.75573 1.000 43.88268 ? 175 ARG A CZ  1 
ATOM   1398 N  NH1 . ARG A  1 175 ? 51.65161 31.17380  -12.83298 1.000 38.44177 ? 175 ARG A NH1 1 
ATOM   1399 N  NH2 . ARG A  1 175 ? 51.53763 33.08084  -11.57038 1.000 39.56819 ? 175 ARG A NH2 1 
ATOM   1400 N  N   . GLU A  1 176 ? 49.42799 31.62242  -20.23563 1.000 23.70051 ? 176 GLU A N   1 
ATOM   1401 C  CA  . GLU A  1 176 ? 49.46176 31.32839  -21.66366 1.000 25.41434 ? 176 GLU A CA  1 
ATOM   1402 C  C   . GLU A  1 176 ? 48.45486 32.17887  -22.42721 1.000 26.69503 ? 176 GLU A C   1 
ATOM   1403 O  O   . GLU A  1 176 ? 48.77337 32.72190  -23.49169 1.000 22.35290 ? 176 GLU A O   1 
ATOM   1404 C  CB  . GLU A  1 176 ? 49.18832 29.84462  -21.89976 1.000 17.98309 ? 176 GLU A CB  1 
ATOM   1405 C  CG  . GLU A  1 176 ? 49.01801 29.48535  -23.36153 1.000 24.80965 ? 176 GLU A CG  1 
ATOM   1406 C  CD  . GLU A  1 176 ? 48.72350 28.01748  -23.56731 1.000 36.77986 ? 176 GLU A CD  1 
ATOM   1407 O  OE1 . GLU A  1 176 ? 47.76496 27.50477  -22.95112 1.000 30.96045 ? 176 GLU A OE1 1 
ATOM   1408 O  OE2 . GLU A  1 176 ? 49.46162 27.37136  -24.33838 1.000 34.59328 ? 176 GLU A OE2 1 
ATOM   1409 N  N   . GLU A  1 177 ? 47.23214 32.30076  -21.90367 1.000 24.27438 ? 177 GLU A N   1 
ATOM   1410 C  CA  . GLU A  1 177 ? 46.21781 33.09684  -22.58566 1.000 21.93767 ? 177 GLU A CA  1 
ATOM   1411 C  C   . GLU A  1 177 ? 46.59557 34.57235  -22.60355 1.000 26.25205 ? 177 GLU A C   1 
ATOM   1412 O  O   . GLU A  1 177 ? 46.38998 35.25892  -23.61143 1.000 26.81227 ? 177 GLU A O   1 
ATOM   1413 C  CB  . GLU A  1 177 ? 44.85667 32.90322  -21.91943 1.000 22.28241 ? 177 GLU A CB  1 
ATOM   1414 C  CG  . GLU A  1 177 ? 43.69092 33.40056  -22.75699 1.000 18.99078 ? 177 GLU A CG  1 
ATOM   1415 C  CD  . GLU A  1 177 ? 42.44063 33.64210  -21.93635 1.000 22.00193 ? 177 GLU A CD  1 
ATOM   1416 O  OE1 . GLU A  1 177 ? 42.46834 34.53213  -21.06108 1.000 24.37127 ? 177 GLU A OE1 1 
ATOM   1417 O  OE2 . GLU A  1 177 ? 41.43177 32.94142  -22.16389 1.000 17.87856 ? 177 GLU A OE2 1 
ATOM   1418 N  N   . ARG A  1 178 ? 47.14987 35.07861  -21.49837 1.000 27.50737 ? 178 ARG A N   1 
ATOM   1419 C  CA  . ARG A  1 178 ? 47.55500 36.47900  -21.45777 1.000 24.78436 ? 178 ARG A CA  1 
ATOM   1420 C  C   . ARG A  1 178 ? 48.77448 36.73851  -22.33201 1.000 19.25305 ? 178 ARG A C   1 
ATOM   1421 O  O   . ARG A  1 178 ? 48.91722 37.83899  -22.87604 1.000 21.49215 ? 178 ARG A O   1 
ATOM   1422 C  CB  . ARG A  1 178 ? 47.83458 36.91104  -20.01960 1.000 26.78990 ? 178 ARG A CB  1 
ATOM   1423 C  CG  . ARG A  1 178 ? 46.61628 36.90993  -19.11399 1.000 29.52514 ? 178 ARG A CG  1 
ATOM   1424 C  CD  . ARG A  1 178 ? 46.94265 37.57412  -17.78718 1.000 33.45362 ? 178 ARG A CD  1 
ATOM   1425 N  NE  . ARG A  1 178 ? 46.01579 37.19727  -16.72744 1.000 28.63155 ? 178 ARG A NE  1 
ATOM   1426 C  CZ  . ARG A  1 178 ? 45.04211 37.97118  -16.26807 1.000 33.43228 ? 178 ARG A CZ  1 
ATOM   1427 N  NH1 . ARG A  1 178 ? 44.82496 39.17893  -16.76221 1.000 30.18896 ? 178 ARG A NH1 1 
ATOM   1428 N  NH2 . ARG A  1 178 ? 44.27113 37.52480  -15.28243 1.000 32.44937 ? 178 ARG A NH2 1 
ATOM   1429 N  N   . SER A  1 179 ? 49.66183 35.74890  -22.47870 1.000 20.28272 ? 179 SER A N   1 
ATOM   1430 C  CA  . SER A  1 179 ? 50.79234 35.90859  -23.38874 1.000 22.01731 ? 179 SER A CA  1 
ATOM   1431 C  C   . SER A  1 179 ? 50.32011 36.18757  -24.80807 1.000 23.41167 ? 179 SER A C   1 
ATOM   1432 O  O   . SER A  1 179 ? 51.01307 36.86870  -25.57214 1.000 28.29223 ? 179 SER A O   1 
ATOM   1433 C  CB  . SER A  1 179 ? 51.68234 34.66601  -23.35880 1.000 16.09628 ? 179 SER A CB  1 
ATOM   1434 O  OG  . SER A  1 179 ? 51.03320 33.55543  -23.95152 1.000 28.33925 ? 179 SER A OG  1 
ATOM   1435 N  N   . LEU A  1 180 ? 49.14987 35.67297  -25.17551 1.000 23.78685 ? 180 LEU A N   1 
ATOM   1436 C  CA  . LEU A  1 180 ? 48.51465 36.05341  -26.42847 1.000 23.84735 ? 180 LEU A CA  1 
ATOM   1437 C  C   . LEU A  1 180 ? 47.92948 37.45153  -26.28178 1.000 30.33782 ? 180 LEU A C   1 
ATOM   1438 O  O   . LEU A  1 180 ? 47.04967 37.67843  -25.44374 1.000 43.49403 ? 180 LEU A O   1 
ATOM   1439 C  CB  . LEU A  1 180 ? 47.42447 35.05018  -26.79646 1.000 24.55553 ? 180 LEU A CB  1 
ATOM   1440 C  CG  . LEU A  1 180 ? 47.77020 33.56499  -26.66555 1.000 23.06456 ? 180 LEU A CG  1 
ATOM   1441 C  CD1 . LEU A  1 180 ? 46.54915 32.70855  -26.95721 1.000 22.30975 ? 180 LEU A CD1 1 
ATOM   1442 C  CD2 . LEU A  1 180 ? 48.92147 33.19066  -27.58404 1.000 17.01542 ? 180 LEU A CD2 1 
ATOM   1443 N  N   . ASN A  1 181 ? 48.41838 38.39096  -27.08827 1.000 31.15147 ? 181 ASN A N   1 
ATOM   1444 C  CA  . ASN A  1 181 ? 47.95537 39.77145  -27.01279 1.000 29.90076 ? 181 ASN A CA  1 
ATOM   1445 C  C   . ASN A  1 181 ? 46.53580 39.88659  -27.55933 1.000 26.48047 ? 181 ASN A C   1 
ATOM   1446 O  O   . ASN A  1 181 ? 46.29815 40.57550  -28.55686 1.000 31.06841 ? 181 ASN A O   1 
ATOM   1447 C  CB  . ASN A  1 181 ? 48.91332 40.69172  -27.77584 1.000 26.59946 ? 181 ASN A CB  1 
ATOM   1448 C  CG  . ASN A  1 181 ? 48.60896 42.16054  -27.56454 1.000 26.87389 ? 181 ASN A CG  1 
ATOM   1449 O  OD1 . ASN A  1 181 ? 48.19897 42.57385  -26.48036 1.000 35.13510 ? 181 ASN A OD1 1 
ATOM   1450 N  ND2 . ASN A  1 181 ? 48.80211 42.95765  -28.60707 1.000 28.22950 ? 181 ASN A ND2 1 
ATOM   1451 N  N   . LEU A  1 182 ? 45.58742 39.21683  -26.91191 1.000 21.01001 ? 182 LEU A N   1 
ATOM   1452 C  CA  . LEU A  1 182 ? 44.21648 39.17470  -27.38842 1.000 20.58789 ? 182 LEU A CA  1 
ATOM   1453 C  C   . LEU A  1 182 ? 43.48392 40.46754  -27.04877 1.000 21.43523 ? 182 LEU A C   1 
ATOM   1454 O  O   . LEU A  1 182 ? 43.86980 41.18650  -26.12393 1.000 24.01994 ? 182 LEU A O   1 
ATOM   1455 C  CB  . LEU A  1 182 ? 43.48524 37.98621  -26.77253 1.000 21.06725 ? 182 LEU A CB  1 
ATOM   1456 C  CG  . LEU A  1 182 ? 44.00472 36.59133  -27.12570 1.000 21.99369 ? 182 LEU A CG  1 
ATOM   1457 C  CD1 . LEU A  1 182 ? 43.23525 35.52700  -26.35882 1.000 17.93739 ? 182 LEU A CD1 1 
ATOM   1458 C  CD2 . LEU A  1 182 ? 43.91432 36.34875  -28.62233 1.000 17.33466 ? 182 LEU A CD2 1 
ATOM   1459 N  N   . PRO A  1 183 ? 42.43265 40.79723  -27.80019 1.000 17.79154 ? 183 PRO A N   1 
ATOM   1460 C  CA  . PRO A  1 183 ? 41.57267 41.92744  -27.41651 1.000 14.48522 ? 183 PRO A CA  1 
ATOM   1461 C  C   . PRO A  1 183 ? 41.04725 41.75097  -26.00037 1.000 17.71279 ? 183 PRO A C   1 
ATOM   1462 O  O   . PRO A  1 183 ? 40.37243 40.76803  -25.68632 1.000 16.86563 ? 183 PRO A O   1 
ATOM   1463 C  CB  . PRO A  1 183 ? 40.44611 41.87664  -28.45404 1.000 15.45509 ? 183 PRO A CB  1 
ATOM   1464 C  CG  . PRO A  1 183 ? 41.07872 41.25117  -29.64923 1.000 17.46728 ? 183 PRO A CG  1 
ATOM   1465 C  CD  . PRO A  1 183 ? 42.05559 40.23700  -29.11043 1.000 14.58250 ? 183 PRO A CD  1 
ATOM   1466 N  N   . LYS A  1 184 ? 41.36327 42.71576  -25.14121 1.000 22.19797 ? 184 LYS A N   1 
ATOM   1467 C  CA  . LYS A  1 184 ? 41.06335 42.63571  -23.71827 1.000 21.04626 ? 184 LYS A CA  1 
ATOM   1468 C  C   . LYS A  1 184 ? 40.28581 43.87420  -23.28855 1.000 20.64085 ? 184 LYS A C   1 
ATOM   1469 O  O   . LYS A  1 184 ? 39.97328 44.75149  -24.09879 1.000 17.53267 ? 184 LYS A O   1 
ATOM   1470 C  CB  . LYS A  1 184 ? 42.35178 42.49308  -22.90074 1.000 21.88467 ? 184 LYS A CB  1 
ATOM   1471 C  CG  . LYS A  1 184 ? 43.46501 43.42001  -23.37482 1.000 31.79033 ? 184 LYS A CG  1 
ATOM   1472 C  CD  . LYS A  1 184 ? 44.62433 43.44774  -22.39558 1.000 32.67055 ? 184 LYS A CD  1 
ATOM   1473 C  CE  . LYS A  1 184 ? 45.19483 42.05665  -22.18280 1.000 34.99178 ? 184 LYS A CE  1 
ATOM   1474 N  NZ  . LYS A  1 184 ? 45.86892 41.53740  -23.40329 1.000 29.83228 ? 184 LYS A NZ  1 
ATOM   1475 N  N   . GLY A  1 185 ? 39.97326 43.93705  -21.99630 1.000 16.76867 ? 185 GLY A N   1 
ATOM   1476 C  CA  . GLY A  1 185 ? 39.30111 45.10911  -21.45586 1.000 16.21501 ? 185 GLY A CA  1 
ATOM   1477 C  C   . GLY A  1 185 ? 37.91462 45.26330  -22.04294 1.000 17.73222 ? 185 GLY A C   1 
ATOM   1478 O  O   . GLY A  1 185 ? 37.14381 44.30184  -22.13813 1.000 23.57600 ? 185 GLY A O   1 
ATOM   1479 N  N   . GLU A  1 186 ? 37.58848 46.49239  -22.44694 1.000 28.36138 ? 186 GLU A N   1 
ATOM   1480 C  CA  . GLU A  1 186 ? 36.30241 46.77374  -23.07075 1.000 24.27067 ? 186 GLU A CA  1 
ATOM   1481 C  C   . GLU A  1 186 ? 36.17620 46.15321  -24.45390 1.000 24.08682 ? 186 GLU A C   1 
ATOM   1482 O  O   . GLU A  1 186 ? 35.06832 46.11949  -24.99997 1.000 24.88135 ? 186 GLU A O   1 
ATOM   1483 C  CB  . GLU A  1 186 ? 36.08759 48.28493  -23.16571 1.000 18.93062 ? 186 GLU A CB  1 
ATOM   1484 C  CG  . GLU A  1 186 ? 36.88747 48.94906  -24.27615 1.000 29.04342 ? 186 GLU A CG  1 
ATOM   1485 C  CD  . GLU A  1 186 ? 36.98217 50.45263  -24.11017 1.000 44.14946 ? 186 GLU A CD  1 
ATOM   1486 O  OE1 . GLU A  1 186 ? 37.76576 50.90742  -23.24930 1.000 53.74814 ? 186 GLU A OE1 1 
ATOM   1487 O  OE2 . GLU A  1 186 ? 36.26908 51.17899  -24.83492 1.000 44.15304 ? 186 GLU A OE2 1 
ATOM   1488 N  N   . TYR A  1 187 ? 37.27404 45.67053  -25.02924 1.000 21.80535 ? 187 TYR A N   1 
ATOM   1489 C  CA  . TYR A  1 187 ? 37.26382 45.06153  -26.35040 1.000 24.00275 ? 187 TYR A CA  1 
ATOM   1490 C  C   . TYR A  1 187 ? 37.08659 43.55139  -26.29695 1.000 19.07013 ? 187 TYR A C   1 
ATOM   1491 O  O   . TYR A  1 187 ? 37.11164 42.89878  -27.34560 1.000 20.18970 ? 187 TYR A O   1 
ATOM   1492 C  CB  . TYR A  1 187 ? 38.54849 45.43173  -27.09500 1.000 19.59783 ? 187 TYR A CB  1 
ATOM   1493 C  CG  . TYR A  1 187 ? 38.81534 46.91616  -27.04091 1.000 25.85776 ? 187 TYR A CG  1 
ATOM   1494 C  CD1 . TYR A  1 187 ? 38.04950 47.80362  -27.78638 1.000 28.53567 ? 187 TYR A CD1 1 
ATOM   1495 C  CD2 . TYR A  1 187 ? 39.80976 47.43541  -26.22198 1.000 27.71259 ? 187 TYR A CD2 1 
ATOM   1496 C  CE1 . TYR A  1 187 ? 38.27659 49.16448  -27.73088 1.000 27.34667 ? 187 TYR A CE1 1 
ATOM   1497 C  CE2 . TYR A  1 187 ? 40.04531 48.79536  -26.16124 1.000 25.94728 ? 187 TYR A CE2 1 
ATOM   1498 C  CZ  . TYR A  1 187 ? 39.27516 49.65511  -26.91776 1.000 29.74333 ? 187 TYR A CZ  1 
ATOM   1499 O  OH  . TYR A  1 187 ? 39.50234 51.01128  -26.86238 1.000 37.11521 ? 187 TYR A OH  1 
ATOM   1500 N  N   . GLU A  1 188 ? 36.91440 42.98813  -25.10399 1.000 21.22531 ? 188 GLU A N   1 
ATOM   1501 C  CA  . GLU A  1 188 ? 36.47213 41.61111  -24.91915 1.000 19.04081 ? 188 GLU A CA  1 
ATOM   1502 C  C   . GLU A  1 188 ? 35.04957 41.67364  -24.37765 1.000 19.44142 ? 188 GLU A C   1 
ATOM   1503 O  O   . GLU A  1 188 ? 34.83098 42.11634  -23.24521 1.000 21.11247 ? 188 GLU A O   1 
ATOM   1504 C  CB  . GLU A  1 188 ? 37.39512 40.84946  -23.97125 1.000 14.71908 ? 188 GLU A CB  1 
ATOM   1505 C  CG  . GLU A  1 188 ? 36.92301 39.43737  -23.66387 1.000 16.63253 ? 188 GLU A CG  1 
ATOM   1506 C  CD  . GLU A  1 188 ? 37.74295 38.76772  -22.58025 1.000 18.40148 ? 188 GLU A CD  1 
ATOM   1507 O  OE1 . GLU A  1 188 ? 38.84949 39.26096  -22.27357 1.000 27.91983 ? 188 GLU A OE1 1 
ATOM   1508 O  OE2 . GLU A  1 188 ? 37.27679 37.74938  -22.03040 1.000 16.76694 ? 188 GLU A OE2 1 
ATOM   1509 N  N   . ILE A  1 189 ? 34.08692 41.24363  -25.18624 1.000 21.17306 ? 189 ILE A N   1 
ATOM   1510 C  CA  . ILE A  1 189 ? 32.66831 41.38211  -24.88409 1.000 20.03208 ? 189 ILE A CA  1 
ATOM   1511 C  C   . ILE A  1 189 ? 32.06832 39.98835  -24.76997 1.000 20.06446 ? 189 ILE A C   1 
ATOM   1512 O  O   . ILE A  1 189 ? 32.20662 39.18996  -25.69794 1.000 20.67744 ? 189 ILE A O   1 
ATOM   1513 C  CB  . ILE A  1 189 ? 31.91806 42.19588  -25.95388 1.000 21.58845 ? 189 ILE A CB  1 
ATOM   1514 C  CG1 . ILE A  1 189 ? 32.44434 43.63118  -25.99633 1.000 18.80684 ? 189 ILE A CG1 1 
ATOM   1515 C  CG2 . ILE A  1 189 ? 30.41897 42.16597  -25.69412 1.000 15.07358 ? 189 ILE A CG2 1 
ATOM   1516 C  CD1 . ILE A  1 189 ? 31.91432 44.43502  -27.15958 1.000 21.51910 ? 189 ILE A CD1 1 
ATOM   1517 N  N   . PRO A  1 190 ? 31.40373 39.65200  -23.66542 1.000 18.78319 ? 190 PRO A N   1 
ATOM   1518 C  CA  . PRO A  1 190 ? 30.70412 38.36616  -23.58167 1.000 16.45516 ? 190 PRO A CA  1 
ATOM   1519 C  C   . PRO A  1 190 ? 29.28588 38.45664  -24.12350 1.000 15.80149 ? 190 PRO A C   1 
ATOM   1520 O  O   . PRO A  1 190 ? 28.57870 39.44951  -23.93848 1.000 17.94597 ? 190 PRO A O   1 
ATOM   1521 C  CB  . PRO A  1 190 ? 30.70207 38.08448  -22.07448 1.000 15.30456 ? 190 PRO A CB  1 
ATOM   1522 C  CG  . PRO A  1 190 ? 30.62750 39.44345  -21.46241 1.000 21.22027 ? 190 PRO A CG  1 
ATOM   1523 C  CD  . PRO A  1 190 ? 31.39563 40.37120  -22.37924 1.000 18.45142 ? 190 PRO A CD  1 
ATOM   1524 N  N   . LEU A  1 191 ? 28.86682 37.39432  -24.80627 1.000 15.49809 ? 191 LEU A N   1 
ATOM   1525 C  CA  . LEU A  1 191 ? 27.54756 37.32340  -25.43290 1.000 13.50875 ? 191 LEU A CA  1 
ATOM   1526 C  C   . LEU A  1 191 ? 26.79973 36.12629  -24.85325 1.000 15.32231 ? 191 LEU A C   1 
ATOM   1527 O  O   . LEU A  1 191 ? 26.89521 35.01066  -25.37049 1.000 18.34186 ? 191 LEU A O   1 
ATOM   1528 C  CB  . LEU A  1 191 ? 27.66705 37.22644  -26.95426 1.000 12.04692 ? 191 LEU A CB  1 
ATOM   1529 C  CG  . LEU A  1 191 ? 28.32787 38.41351  -27.65598 1.000 14.52295 ? 191 LEU A CG  1 
ATOM   1530 C  CD1 . LEU A  1 191 ? 28.36801 38.19347  -29.15850 1.000 14.86161 ? 191 LEU A CD1 1 
ATOM   1531 C  CD2 . LEU A  1 191 ? 27.60103 39.70543  -27.31884 1.000 17.71930 ? 191 LEU A CD2 1 
ATOM   1532 N  N   . LEU A  1 192 ? 26.05356 36.36312  -23.77467 1.000 16.73348 ? 192 LEU A N   1 
ATOM   1533 C  CA  . LEU A  1 192 ? 25.20916 35.33505  -23.16693 1.000 12.13659 ? 192 LEU A CA  1 
ATOM   1534 C  C   . LEU A  1 192 ? 23.85856 35.39215  -23.86966 1.000 16.35809 ? 192 LEU A C   1 
ATOM   1535 O  O   . LEU A  1 192 ? 22.96840 36.15762  -23.49662 1.000 15.56883 ? 192 LEU A O   1 
ATOM   1536 C  CB  . LEU A  1 192 ? 25.09057 35.55138  -21.66275 1.000 11.45688 ? 192 LEU A CB  1 
ATOM   1537 C  CG  . LEU A  1 192 ? 24.59473 34.38775  -20.79615 1.000 13.83021 ? 192 LEU A CG  1 
ATOM   1538 C  CD1 . LEU A  1 192 ? 25.05861 34.56454  -19.36031 1.000 14.20965 ? 192 LEU A CD1 1 
ATOM   1539 C  CD2 . LEU A  1 192 ? 23.08139 34.25957  -20.84119 1.000 14.75454 ? 192 LEU A CD2 1 
ATOM   1540 N  N   . ILE A  1 193 ? 23.70637 34.56567  -24.90005 1.000 18.49310 ? 193 ILE A N   1 
ATOM   1541 C  CA  . ILE A  1 193 ? 22.53239 34.59440  -25.76527 1.000 21.94836 ? 193 ILE A CA  1 
ATOM   1542 C  C   . ILE A  1 193 ? 21.47461 33.64727  -25.21336 1.000 20.35508 ? 193 ILE A C   1 
ATOM   1543 O  O   . ILE A  1 193 ? 21.77156 32.49361  -24.87972 1.000 20.29188 ? 193 ILE A O   1 
ATOM   1544 C  CB  . ILE A  1 193 ? 22.91049 34.21950  -27.20748 1.000 15.86769 ? 193 ILE A CB  1 
ATOM   1545 C  CG1 . ILE A  1 193 ? 24.07122 35.09068  -27.69139 1.000 12.85962 ? 193 ILE A CG1 1 
ATOM   1546 C  CG2 . ILE A  1 193 ? 21.71063 34.36336  -28.12903 1.000 16.03292 ? 193 ILE A CG2 1 
ATOM   1547 C  CD1 . ILE A  1 193 ? 24.52569 34.77755  -29.09744 1.000 15.71066 ? 193 ILE A CD1 1 
ATOM   1548 N  N   . GLN A  1 194 ? 20.23686 34.13322  -25.12339 1.000 19.17182 ? 194 GLN A N   1 
ATOM   1549 C  CA  . GLN A  1 194 ? 19.12369 33.34336  -24.61583 1.000 23.74108 ? 194 GLN A CA  1 
ATOM   1550 C  C   . GLN A  1 194 ? 17.85424 33.72483  -25.36203 1.000 22.71053 ? 194 GLN A C   1 
ATOM   1551 O  O   . GLN A  1 194 ? 17.74592 34.81612  -25.92695 1.000 21.09468 ? 194 GLN A O   1 
ATOM   1552 C  CB  . GLN A  1 194 ? 18.91681 33.54891  -23.11037 1.000 22.02362 ? 194 GLN A CB  1 
ATOM   1553 C  CG  . GLN A  1 194 ? 19.95235 32.88906  -22.22501 1.000 16.11581 ? 194 GLN A CG  1 
ATOM   1554 C  CD  . GLN A  1 194 ? 19.72956 33.19907  -20.76046 1.000 19.99745 ? 194 GLN A CD  1 
ATOM   1555 O  OE1 . GLN A  1 194 ? 19.42460 34.33405  -20.39610 1.000 27.58053 ? 194 GLN A OE1 1 
ATOM   1556 N  NE2 . GLN A  1 194 ? 19.87118 32.18864  -19.91189 1.000 20.54996 ? 194 GLN A NE2 1 
ATOM   1557 N  N   . ASP A  1 195 ? 16.88416 32.81450  -25.34421 1.000 19.62111 ? 195 ASP A N   1 
ATOM   1558 C  CA  . ASP A  1 195 ? 15.57473 33.05403  -25.93198 1.000 22.65445 ? 195 ASP A CA  1 
ATOM   1559 C  C   . ASP A  1 195 ? 14.50679 32.97325  -24.84950 1.000 21.80698 ? 195 ASP A C   1 
ATOM   1560 O  O   . ASP A  1 195 ? 14.60153 32.15424  -23.92959 1.000 20.78978 ? 195 ASP A O   1 
ATOM   1561 C  CB  . ASP A  1 195 ? 15.27184 32.05498  -27.05622 1.000 22.26331 ? 195 ASP A CB  1 
ATOM   1562 C  CG  . ASP A  1 195 ? 15.11891 30.63515  -26.55448 1.000 21.74698 ? 195 ASP A CG  1 
ATOM   1563 O  OD1 . ASP A  1 195 ? 15.79009 30.27060  -25.56756 1.000 24.14169 ? 195 ASP A OD1 1 
ATOM   1564 O  OD2 . ASP A  1 195 ? 14.32407 29.88221  -27.15291 1.000 16.97258 ? 195 ASP A OD2 1 
ATOM   1565 N  N   . LYS A  1 196 ? 13.49248 33.82894  -24.96251 1.000 22.05183 ? 196 LYS A N   1 
ATOM   1566 C  CA  . LYS A  1 196 ? 12.44452 33.91813  -23.95614 1.000 19.20785 ? 196 LYS A CA  1 
ATOM   1567 C  C   . LYS A  1 196 ? 11.14429 34.35836  -24.61363 1.000 21.35547 ? 196 LYS A C   1 
ATOM   1568 O  O   . LYS A  1 196 ? 11.11978 34.79856  -25.76577 1.000 19.25225 ? 196 LYS A O   1 
ATOM   1569 C  CB  . LYS A  1 196 ? 12.82764 34.88893  -22.83268 1.000 18.88801 ? 196 LYS A CB  1 
ATOM   1570 C  CG  . LYS A  1 196 ? 13.67697 34.27826  -21.73228 1.000 23.65719 ? 196 LYS A CG  1 
ATOM   1571 C  CD  . LYS A  1 196 ? 14.07909 35.31727  -20.69931 1.000 17.91492 ? 196 LYS A CD  1 
ATOM   1572 C  CE  . LYS A  1 196 ? 14.54008 34.65811  -19.40696 1.000 16.07213 ? 196 LYS A CE  1 
ATOM   1573 N  NZ  . LYS A  1 196 ? 15.64051 33.68433  -19.63234 1.000 16.72157 ? 196 LYS A NZ  1 
ATOM   1574 N  N   . SER A  1 197 ? 10.05528 34.22759  -23.85798 1.000 23.31131 ? 197 SER A N   1 
ATOM   1575 C  CA  . SER A  1 197 ? 8.74641  34.72787  -24.25045 1.000 21.33446 ? 197 SER A CA  1 
ATOM   1576 C  C   . SER A  1 197 ? 8.14050  35.49642  -23.08566 1.000 24.12365 ? 197 SER A C   1 
ATOM   1577 O  O   . SER A  1 197 ? 8.37666  35.17363  -21.91817 1.000 22.02445 ? 197 SER A O   1 
ATOM   1578 C  CB  . SER A  1 197 ? 7.80494  33.59625  -24.67845 1.000 20.29152 ? 197 SER A CB  1 
ATOM   1579 O  OG  . SER A  1 197 ? 8.19899  33.05191  -25.92492 1.000 19.21576 ? 197 SER A OG  1 
ATOM   1580 N  N   . PHE A  1 198 ? 7.35405  36.51786  -23.41176 1.000 23.25645 ? 198 PHE A N   1 
ATOM   1581 C  CA  . PHE A  1 198 ? 6.82743  37.43303  -22.41306 1.000 18.71661 ? 198 PHE A CA  1 
ATOM   1582 C  C   . PHE A  1 198 ? 5.32096  37.57469  -22.55952 1.000 17.50280 ? 198 PHE A C   1 
ATOM   1583 O  O   . PHE A  1 198 ? 4.77993  37.54227  -23.66822 1.000 16.27044 ? 198 PHE A O   1 
ATOM   1584 C  CB  . PHE A  1 198 ? 7.47513  38.82015  -22.52697 1.000 18.29155 ? 198 PHE A CB  1 
ATOM   1585 C  CG  . PHE A  1 198 ? 8.96652  38.81136  -22.36234 1.000 24.43354 ? 198 PHE A CG  1 
ATOM   1586 C  CD1 . PHE A  1 198 ? 9.79601  38.58502  -23.44889 1.000 20.09656 ? 198 PHE A CD1 1 
ATOM   1587 C  CD2 . PHE A  1 198 ? 9.54048  39.03879  -21.12206 1.000 22.72898 ? 198 PHE A CD2 1 
ATOM   1588 C  CE1 . PHE A  1 198 ? 11.16967 38.57932  -23.30035 1.000 18.21356 ? 198 PHE A CE1 1 
ATOM   1589 C  CE2 . PHE A  1 198 ? 10.91308 39.03453  -20.96734 1.000 21.88792 ? 198 PHE A CE2 1 
ATOM   1590 C  CZ  . PHE A  1 198 ? 11.72900 38.80459  -22.05928 1.000 18.28862 ? 198 PHE A CZ  1 
ATOM   1591 N  N   . HIS A  1 199 ? 4.64987  37.73019  -21.42201 1.000 19.35604 ? 199 HIS A N   1 
ATOM   1592 C  CA  . HIS A  1 199 ? 3.27258  38.18864  -21.41939 1.000 22.77130 ? 199 HIS A CA  1 
ATOM   1593 C  C   . HIS A  1 199 ? 3.23112  39.69314  -21.67342 1.000 23.88123 ? 199 HIS A C   1 
ATOM   1594 O  O   . HIS A  1 199 ? 4.25665  40.37966  -21.67189 1.000 25.33048 ? 199 HIS A O   1 
ATOM   1595 C  CB  . HIS A  1 199 ? 2.59303  37.87559  -20.08551 1.000 22.88389 ? 199 HIS A CB  1 
ATOM   1596 C  CG  . HIS A  1 199 ? 2.55182  36.41864  -19.74432 1.000 27.06845 ? 199 HIS A CG  1 
ATOM   1597 N  ND1 . HIS A  1 199 ? 1.63150  35.55095  -20.29207 1.000 25.11515 ? 199 HIS A ND1 1 
ATOM   1598 C  CD2 . HIS A  1 199 ? 3.30349  35.68116  -18.89275 1.000 27.11229 ? 199 HIS A CD2 1 
ATOM   1599 C  CE1 . HIS A  1 199 ? 1.82502  34.33971  -19.80111 1.000 22.53050 ? 199 HIS A CE1 1 
ATOM   1600 N  NE2 . HIS A  1 199 ? 2.83370  34.39143  -18.94975 1.000 22.72252 ? 199 HIS A NE2 1 
ATOM   1601 N  N   . GLU A  1 200 ? 2.02016  40.21257  -21.88920 1.000 29.20963 ? 200 GLU A N   1 
ATOM   1602 C  CA  . GLU A  1 200 ? 1.84079  41.66021  -21.86200 1.000 28.47719 ? 200 GLU A CA  1 
ATOM   1603 C  C   . GLU A  1 200 ? 2.20490  42.22055  -20.49514 1.000 26.14610 ? 200 GLU A C   1 
ATOM   1604 O  O   . GLU A  1 200 ? 2.57623  43.39471  -20.37803 1.000 26.96343 ? 200 GLU A O   1 
ATOM   1605 C  CB  . GLU A  1 200 ? 0.39959  42.01928  -22.22136 1.000 30.39276 ? 200 GLU A CB  1 
ATOM   1606 C  CG  . GLU A  1 200 ? -0.07201 41.45262  -23.55057 1.000 31.21097 ? 200 GLU A CG  1 
ATOM   1607 C  CD  . GLU A  1 200 ? 0.51350  42.18663  -24.73947 1.000 41.63925 ? 200 GLU A CD  1 
ATOM   1608 O  OE1 . GLU A  1 200 ? 1.00391  43.32048  -24.55615 1.000 41.41493 ? 200 GLU A OE1 1 
ATOM   1609 O  OE2 . GLU A  1 200 ? 0.48161  41.63078  -25.85798 1.000 48.40721 ? 200 GLU A OE2 1 
ATOM   1610 N  N   . ASP A  1 201 ? 2.10457  41.38318  -19.45742 1.000 33.39932 ? 201 ASP A N   1 
ATOM   1611 C  CA  . ASP A  1 201 ? 2.53103  41.74608  -18.11098 1.000 28.36263 ? 201 ASP A CA  1 
ATOM   1612 C  C   . ASP A  1 201 ? 3.98805  42.18993  -18.07307 1.000 29.58086 ? 201 ASP A C   1 
ATOM   1613 O  O   . ASP A  1 201 ? 4.38006  42.95806  -17.18707 1.000 29.08710 ? 201 ASP A O   1 
ATOM   1614 C  CB  . ASP A  1 201 ? 2.32645  40.54806  -17.18056 1.000 23.22590 ? 201 ASP A CB  1 
ATOM   1615 C  CG  . ASP A  1 201 ? 1.78697  40.94390  -15.82835 1.000 42.06748 ? 201 ASP A CG  1 
ATOM   1616 O  OD1 . ASP A  1 201 ? 1.33116  42.09474  -15.68015 1.000 51.10451 ? 201 ASP A OD1 1 
ATOM   1617 O  OD2 . ASP A  1 201 ? 1.84821  40.10929  -14.90289 1.000 51.20318 ? 201 ASP A OD2 1 
ATOM   1618 N  N   . GLY A  1 202 ? 4.79737  41.73171  -19.02738 1.000 23.01053 ? 202 GLY A N   1 
ATOM   1619 C  CA  . GLY A  1 202 ? 6.23343  41.84356  -18.94220 1.000 21.17567 ? 202 GLY A CA  1 
ATOM   1620 C  C   . GLY A  1 202 ? 6.89608  40.68130  -18.23929 1.000 25.35324 ? 202 GLY A C   1 
ATOM   1621 O  O   . GLY A  1 202 ? 8.12958  40.58088  -18.26203 1.000 25.66841 ? 202 GLY A O   1 
ATOM   1622 N  N   . SER A  1 203 ? 6.11484  39.80131  -17.62097 1.000 20.14064 ? 203 SER A N   1 
ATOM   1623 C  CA  . SER A  1 203 ? 6.64455  38.65064  -16.91511 1.000 21.42223 ? 203 SER A CA  1 
ATOM   1624 C  C   . SER A  1 203 ? 6.97704  37.53054  -17.89860 1.000 24.29966 ? 203 SER A C   1 
ATOM   1625 O  O   . SER A  1 203 ? 6.55664  37.53616  -19.05875 1.000 22.99605 ? 203 SER A O   1 
ATOM   1626 C  CB  . SER A  1 203 ? 5.64649  38.16771  -15.86325 1.000 23.12134 ? 203 SER A CB  1 
ATOM   1627 O  OG  . SER A  1 203 ? 4.40535  37.81908  -16.45390 1.000 22.84705 ? 203 SER A OG  1 
ATOM   1628 N  N   . LEU A  1 204 ? 7.75177  36.56191  -17.41960 1.000 19.02863 ? 204 LEU A N   1 
ATOM   1629 C  CA  . LEU A  1 204 ? 8.13614  35.43181  -18.25251 1.000 17.68297 ? 204 LEU A CA  1 
ATOM   1630 C  C   . LEU A  1 204 ? 6.94518  34.51807  -18.50240 1.000 24.21814 ? 204 LEU A C   1 
ATOM   1631 O  O   . LEU A  1 204 ? 6.14783  34.24550  -17.60053 1.000 27.26735 ? 204 LEU A O   1 
ATOM   1632 C  CB  . LEU A  1 204 ? 9.25984  34.63462  -17.59259 1.000 17.52097 ? 204 LEU A CB  1 
ATOM   1633 C  CG  . LEU A  1 204 ? 10.58484 35.35070  -17.35282 1.000 15.65464 ? 204 LEU A CG  1 
ATOM   1634 C  CD1 . LEU A  1 204 ? 11.58384 34.39709  -16.72126 1.000 13.68685 ? 204 LEU A CD1 1 
ATOM   1635 C  CD2 . LEU A  1 204 ? 11.11985 35.91635  -18.65653 1.000 17.60344 ? 204 LEU A CD2 1 
ATOM   1636 N  N   . PHE A  1 205 ? 6.83037  34.04021  -19.73608 1.000 25.71539 ? 205 PHE A N   1 
ATOM   1637 C  CA  . PHE A  1 205 ? 5.85561  33.01936  -20.08792 1.000 24.62203 ? 205 PHE A CA  1 
ATOM   1638 C  C   . PHE A  1 205 ? 6.55724  31.67511  -20.21247 1.000 23.73507 ? 205 PHE A C   1 
ATOM   1639 O  O   . PHE A  1 205 ? 7.53687  31.54677  -20.95384 1.000 24.43771 ? 205 PHE A O   1 
ATOM   1640 C  CB  . PHE A  1 205 ? 5.13808  33.35318  -21.39532 1.000 20.88653 ? 205 PHE A CB  1 
ATOM   1641 C  CG  . PHE A  1 205 ? 4.45379  32.17181  -22.01805 1.000 23.03296 ? 205 PHE A CG  1 
ATOM   1642 C  CD1 . PHE A  1 205 ? 3.27527  31.67769  -21.48413 1.000 22.17772 ? 205 PHE A CD1 1 
ATOM   1643 C  CD2 . PHE A  1 205 ? 4.99563  31.54578  -23.12920 1.000 24.12356 ? 205 PHE A CD2 1 
ATOM   1644 C  CE1 . PHE A  1 205 ? 2.64661  30.58464  -22.04965 1.000 26.09081 ? 205 PHE A CE1 1 
ATOM   1645 C  CE2 . PHE A  1 205 ? 4.37093  30.45330  -23.69954 1.000 23.72525 ? 205 PHE A CE2 1 
ATOM   1646 C  CZ  . PHE A  1 205 ? 3.19496  29.97218  -23.15909 1.000 25.74044 ? 205 PHE A CZ  1 
ATOM   1647 N  N   . TYR A  1 206 ? 6.05572  30.67938  -19.48182 1.000 22.25314 ? 206 TYR A N   1 
ATOM   1648 C  CA  . TYR A  1 206 ? 6.53369  29.31636  -19.59168 1.000 21.60007 ? 206 TYR A CA  1 
ATOM   1649 C  C   . TYR A  1 206 ? 5.28538  28.44118  -19.56389 1.000 21.89226 ? 206 TYR A C   1 
ATOM   1650 O  O   . TYR A  1 206 ? 4.42531  28.62234  -18.68261 1.000 25.83201 ? 206 TYR A O   1 
ATOM   1651 C  CB  . TYR A  1 206 ? 7.50009  28.92951  -18.46898 1.000 18.51831 ? 206 TYR A CB  1 
ATOM   1652 C  CG  . TYR A  1 206 ? 8.23815  27.63767  -18.73258 1.000 19.46294 ? 206 TYR A CG  1 
ATOM   1653 C  CD1 . TYR A  1 206 ? 9.36934  27.61533  -19.53753 1.000 20.40727 ? 206 TYR A CD1 1 
ATOM   1654 C  CD2 . TYR A  1 206 ? 7.80031  26.44056  -18.18528 1.000 18.31861 ? 206 TYR A CD2 1 
ATOM   1655 C  CE1 . TYR A  1 206 ? 10.04486 26.43879  -19.78746 1.000 15.97238 ? 206 TYR A CE1 1 
ATOM   1656 C  CE2 . TYR A  1 206 ? 8.46969  25.25831  -18.42928 1.000 20.90384 ? 206 TYR A CE2 1 
ATOM   1657 C  CZ  . TYR A  1 206 ? 9.59156  25.26343  -19.23080 1.000 18.82905 ? 206 TYR A CZ  1 
ATOM   1658 O  OH  . TYR A  1 206 ? 10.26333 24.08860  -19.47642 1.000 17.95650 ? 206 TYR A OH  1 
ATOM   1659 N  N   . PRO A  1 207 ? 5.14876  27.50116  -20.49697 1.000 24.21494 ? 207 PRO A N   1 
ATOM   1660 C  CA  . PRO A  1 207 ? 3.88391  26.76588  -20.62015 1.000 29.67202 ? 207 PRO A CA  1 
ATOM   1661 C  C   . PRO A  1 207 ? 3.62454  25.86454  -19.42286 1.000 30.73120 ? 207 PRO A C   1 
ATOM   1662 O  O   . PRO A  1 207 ? 4.53407  25.22276  -18.89181 1.000 31.54175 ? 207 PRO A O   1 
ATOM   1663 C  CB  . PRO A  1 207 ? 4.07492  25.94845  -21.90267 1.000 25.33623 ? 207 PRO A CB  1 
ATOM   1664 C  CG  . PRO A  1 207 ? 5.55524  25.78723  -22.02211 1.000 20.83148 ? 207 PRO A CG  1 
ATOM   1665 C  CD  . PRO A  1 207 ? 6.14788  27.05882  -21.48416 1.000 19.99870 ? 207 PRO A CD  1 
ATOM   1666 N  N   . ARG A  1 208 ? 2.35969  25.82833  -18.99780 1.000 28.59978 ? 208 ARG A N   1 
ATOM   1667 C  CA  . ARG A  1 208 ? 1.95527  24.92826  -17.92502 1.000 24.63247 ? 208 ARG A CA  1 
ATOM   1668 C  C   . ARG A  1 208 ? 1.78896  23.49850  -18.41712 1.000 29.74793 ? 208 ARG A C   1 
ATOM   1669 O  O   . ARG A  1 208 ? 2.04605  22.55422  -17.66245 1.000 31.13117 ? 208 ARG A O   1 
ATOM   1670 C  CB  . ARG A  1 208 ? 0.64502  25.40465  -17.29502 1.000 34.28758 ? 208 ARG A CB  1 
ATOM   1671 C  CG  . ARG A  1 208 ? 0.70914  26.77501  -16.64670 1.000 33.32755 ? 208 ARG A CG  1 
ATOM   1672 C  CD  . ARG A  1 208 ? -0.61982 27.12835  -15.99958 1.000 35.15879 ? 208 ARG A CD  1 
ATOM   1673 N  NE  . ARG A  1 208 ? -1.04609 26.11567  -15.04064 1.000 32.94465 ? 208 ARG A NE  1 
ATOM   1674 C  CZ  . ARG A  1 208 ? -0.72240 26.11916  -13.75479 1.000 34.28813 ? 208 ARG A CZ  1 
ATOM   1675 N  NH1 . ARG A  1 208 ? 0.03744  27.07023  -13.23603 1.000 28.87783 ? 208 ARG A NH1 1 
ATOM   1676 N  NH2 . ARG A  1 208 ? -1.17271 25.14448  -12.96958 1.000 30.86266 ? 208 ARG A NH2 1 
ATOM   1677 N  N   . GLN A  1 209 ? 1.36174  23.32355  -19.66129 1.000 28.41781 ? 209 GLN A N   1 
ATOM   1678 C  CA  . GLN A  1 209 ? 1.08430  22.00760  -20.21766 1.000 29.14004 ? 209 GLN A CA  1 
ATOM   1679 C  C   . GLN A  1 209 ? 1.41008  22.04287  -21.69980 1.000 33.31022 ? 209 GLN A C   1 
ATOM   1680 O  O   . GLN A  1 209 ? 1.61569  23.11928  -22.27498 1.000 33.11768 ? 209 GLN A O   1 
ATOM   1681 C  CB  . GLN A  1 209 ? -0.38007 21.60644  -19.99769 1.000 30.19818 ? 209 GLN A CB  1 
ATOM   1682 C  CG  . GLN A  1 209 ? -0.72927 21.22788  -18.57078 1.000 30.63269 ? 209 GLN A CG  1 
ATOM   1683 C  CD  . GLN A  1 209 ? -2.21818 21.03214  -18.37547 1.000 40.72861 ? 209 GLN A CD  1 
ATOM   1684 O  OE1 . GLN A  1 209 ? -3.02908 21.79959  -18.89457 1.000 42.60538 ? 209 GLN A OE1 1 
ATOM   1685 N  NE2 . GLN A  1 209 ? -2.58708 19.99647  -17.63018 1.000 42.60414 ? 209 GLN A NE2 1 
ATOM   1686 N  N   . PRO A  1 210 ? 1.47758  20.87136  -22.35463 1.000 32.25151 ? 210 PRO A N   1 
ATOM   1687 C  CA  . PRO A  1 210 ? 1.58660  20.85150  -23.82177 1.000 34.68305 ? 210 PRO A CA  1 
ATOM   1688 C  C   . PRO A  1 210 ? 0.42542  21.54608  -24.52351 1.000 37.86285 ? 210 PRO A C   1 
ATOM   1689 O  O   . PRO A  1 210 ? -0.48345 22.07088  -23.87238 1.000 41.73126 ? 210 PRO A O   1 
ATOM   1690 C  CB  . PRO A  1 210 ? 1.62167  19.35335  -24.14508 1.000 33.59237 ? 210 PRO A CB  1 
ATOM   1691 C  CG  . PRO A  1 210 ? 2.23062  18.73704  -22.93683 1.000 26.88136 ? 210 PRO A CG  1 
ATOM   1692 C  CD  . PRO A  1 210 ? 1.72894  19.54192  -21.76809 1.000 27.12752 ? 210 PRO A CD  1 
ATOM   1693 N  N   . ASP A  1 211 ? 0.43770  21.52693  -25.85888 1.000 47.16029 ? 211 ASP A N   1 
ATOM   1694 C  CA  . ASP A  1 211 ? -0.45637 22.38265  -26.63705 1.000 53.01671 ? 211 ASP A CA  1 
ATOM   1695 C  C   . ASP A  1 211 ? -1.92534 22.06737  -26.36556 1.000 53.85747 ? 211 ASP A C   1 
ATOM   1696 O  O   . ASP A  1 211 ? -2.69458 22.94240  -25.95233 1.000 56.68187 ? 211 ASP A O   1 
ATOM   1697 C  CB  . ASP A  1 211 ? -0.13908 22.24758  -28.12617 1.000 49.12681 ? 211 ASP A CB  1 
ATOM   1698 C  CG  . ASP A  1 211 ? 0.37402  23.54040  -28.72646 1.000 53.69727 ? 211 ASP A CG  1 
ATOM   1699 O  OD1 . ASP A  1 211 ? 0.62921  24.49019  -27.95598 1.000 50.60749 ? 211 ASP A OD1 1 
ATOM   1700 O  OD2 . ASP A  1 211 ? 0.51419  23.61262  -29.96605 1.000 68.35345 ? 211 ASP A OD2 1 
ATOM   1701 N  N   . ASN A  1 212 ? -2.33957 20.82380  -26.61327 1.000 47.35349 ? 212 ASN A N   1 
ATOM   1702 C  CA  . ASN A  1 212 ? -3.71436 20.38897  -26.37788 1.000 50.14183 ? 212 ASN A CA  1 
ATOM   1703 C  C   . ASN A  1 212 ? -3.73262 19.45194  -25.17889 1.000 42.08725 ? 212 ASN A C   1 
ATOM   1704 O  O   . ASN A  1 212 ? -3.69084 18.22418  -25.34135 1.000 39.51157 ? 212 ASN A O   1 
ATOM   1705 C  CB  . ASN A  1 212 ? -4.29691 19.69765  -27.61296 1.000 54.26573 ? 212 ASN A CB  1 
ATOM   1706 C  CG  . ASN A  1 212 ? -5.80236 19.49617  -27.51223 1.000 72.31865 ? 212 ASN A CG  1 
ATOM   1707 O  OD1 . ASN A  1 212 ? -6.28927 18.37390  -27.35782 1.000 71.50447 ? 212 ASN A OD1 1 
ATOM   1708 N  ND2 . ASN A  1 212 ? -6.54733 20.59282  -27.59689 1.000 65.77399 ? 212 ASN A ND2 1 
ATOM   1709 N  N   . PRO A  1 213 ? -3.80500 19.97584  -23.95570 1.000 48.37675 ? 213 PRO A N   1 
ATOM   1710 C  CA  . PRO A  1 213 ? -3.67546 19.12094  -22.76822 1.000 47.20072 ? 213 PRO A CA  1 
ATOM   1711 C  C   . PRO A  1 213 ? -4.92466 18.27803  -22.56356 1.000 53.74410 ? 213 PRO A C   1 
ATOM   1712 O  O   . PRO A  1 213 ? -6.03350 18.80377  -22.43897 1.000 49.56007 ? 213 PRO A O   1 
ATOM   1713 C  CB  . PRO A  1 213 ? -3.47478 20.12697  -21.62993 1.000 47.54963 ? 213 PRO A CB  1 
ATOM   1714 C  CG  . PRO A  1 213 ? -4.17631 21.35799  -22.10205 1.000 51.55964 ? 213 PRO A CG  1 
ATOM   1715 C  CD  . PRO A  1 213 ? -4.02023 21.38952  -23.60089 1.000 45.79974 ? 213 PRO A CD  1 
ATOM   1716 N  N   . SER A  1 214 ? -4.73605 16.95957  -22.53713 1.000 58.44929 ? 214 SER A N   1 
ATOM   1717 C  CA  . SER A  1 214 ? -5.82127 16.05203  -22.21742 1.000 56.27821 ? 214 SER A CA  1 
ATOM   1718 C  C   . SER A  1 214 ? -6.29162 16.29993  -20.78341 1.000 58.94103 ? 214 SER A C   1 
ATOM   1719 O  O   . SER A  1 214 ? -5.53888 16.82421  -19.95859 1.000 66.07913 ? 214 SER A O   1 
ATOM   1720 C  CB  . SER A  1 214 ? -5.36304 14.60530  -22.39988 1.000 57.95312 ? 214 SER A CB  1 
ATOM   1721 O  OG  . SER A  1 214 ? -4.80829 14.41046  -23.69140 1.000 56.97342 ? 214 SER A OG  1 
ATOM   1722 N  N   . PRO A  1 215 ? -7.54201 15.94316  -20.46571 1.000 63.30793 ? 215 PRO A N   1 
ATOM   1723 C  CA  . PRO A  1 215 ? -8.06185 16.25498  -19.11798 1.000 58.07237 ? 215 PRO A CA  1 
ATOM   1724 C  C   . PRO A  1 215 ? -7.25397 15.64149  -17.98417 1.000 59.22968 ? 215 PRO A C   1 
ATOM   1725 O  O   . PRO A  1 215 ? -6.82864 16.36482  -17.07353 1.000 61.20773 ? 215 PRO A O   1 
ATOM   1726 C  CB  . PRO A  1 215 ? -9.49957 15.71099  -19.16470 1.000 59.57475 ? 215 PRO A CB  1 
ATOM   1727 C  CG  . PRO A  1 215 ? -9.53040 14.76438  -20.32249 1.000 68.23577 ? 215 PRO A CG  1 
ATOM   1728 C  CD  . PRO A  1 215 ? -8.56387 15.31379  -21.31841 1.000 68.68006 ? 215 PRO A CD  1 
ATOM   1729 N  N   . ASP A  1 216 ? -7.02449 14.32858  -18.00785 1.000 57.89008 ? 216 ASP A N   1 
ATOM   1730 C  CA  . ASP A  1 216 ? -6.30483 13.67490  -16.92008 1.000 62.73178 ? 216 ASP A CA  1 
ATOM   1731 C  C   . ASP A  1 216 ? -4.79927 13.90673  -16.97094 1.000 57.13197 ? 216 ASP A C   1 
ATOM   1732 O  O   . ASP A  1 216 ? -4.08370 13.39121  -16.10493 1.000 51.16236 ? 216 ASP A O   1 
ATOM   1733 C  CB  . ASP A  1 216 ? -6.59304 12.17048  -16.91555 1.000 67.34146 ? 216 ASP A CB  1 
ATOM   1734 C  CG  . ASP A  1 216 ? -6.22555 11.50184  -18.22268 1.000 73.53268 ? 216 ASP A CG  1 
ATOM   1735 O  OD1 . ASP A  1 216 ? -6.85223 11.82314  -19.25431 1.000 68.74583 ? 216 ASP A OD1 1 
ATOM   1736 O  OD2 . ASP A  1 216 ? -5.30065 10.66234  -18.21927 1.000 82.66039 ? 216 ASP A OD2 1 
ATOM   1737 N  N   . LEU A  1 217 ? -4.30453 14.65081  -17.95499 1.000 59.26869 ? 217 LEU A N   1 
ATOM   1738 C  CA  . LEU A  1 217 ? -2.89962 15.02818  -17.96492 1.000 40.56830 ? 217 LEU A CA  1 
ATOM   1739 C  C   . LEU A  1 217 ? -2.59455 15.88256  -16.73649 1.000 40.57095 ? 217 LEU A C   1 
ATOM   1740 O  O   . LEU A  1 217 ? -3.41198 16.72896  -16.35384 1.000 43.41906 ? 217 LEU A O   1 
ATOM   1741 C  CB  . LEU A  1 217 ? -2.56562 15.80032  -19.24410 1.000 41.97737 ? 217 LEU A CB  1 
ATOM   1742 C  CG  . LEU A  1 217 ? -1.11702 16.21820  -19.51494 1.000 35.65322 ? 217 LEU A CG  1 
ATOM   1743 C  CD1 . LEU A  1 217 ? -0.27604 15.02774  -19.95132 1.000 27.31574 ? 217 LEU A CD1 1 
ATOM   1744 C  CD2 . LEU A  1 217 ? -1.06274 17.32812  -20.55464 1.000 35.89490 ? 217 LEU A CD2 1 
ATOM   1745 N  N   . PRO A  1 218 ? -1.44753 15.68215  -16.08615 1.000 38.20946 ? 218 PRO A N   1 
ATOM   1746 C  CA  . PRO A  1 218 ? -1.13473 16.47913  -14.89452 1.000 35.48558 ? 218 PRO A CA  1 
ATOM   1747 C  C   . PRO A  1 218 ? -1.08958 17.96748  -15.20780 1.000 36.01298 ? 218 PRO A C   1 
ATOM   1748 O  O   . PRO A  1 218 ? -0.79694 18.38408  -16.33050 1.000 31.30316 ? 218 PRO A O   1 
ATOM   1749 C  CB  . PRO A  1 218 ? 0.24111  15.95537  -14.46199 1.000 27.62993 ? 218 PRO A CB  1 
ATOM   1750 C  CG  . PRO A  1 218 ? 0.78596  15.24652  -15.65769 1.000 35.26436 ? 218 PRO A CG  1 
ATOM   1751 C  CD  . PRO A  1 218 ? -0.40479 14.68335  -16.36593 1.000 35.55046 ? 218 PRO A CD  1 
ATOM   1752 N  N   . ASP A  1 219 ? -1.39392 18.76984  -14.19257 1.000 38.81228 ? 219 ASP A N   1 
ATOM   1753 C  CA  . ASP A  1 219 ? -1.43307 20.21551  -14.33330 1.000 32.39273 ? 219 ASP A CA  1 
ATOM   1754 C  C   . ASP A  1 219 ? -0.72070 20.84844  -13.14708 1.000 33.48589 ? 219 ASP A C   1 
ATOM   1755 O  O   . ASP A  1 219 ? -1.20625 20.75109  -12.01027 1.000 35.34355 ? 219 ASP A O   1 
ATOM   1756 C  CB  . ASP A  1 219 ? -2.87839 20.70719  -14.43337 1.000 37.04403 ? 219 ASP A CB  1 
ATOM   1757 C  CG  . ASP A  1 219 ? -2.99567 22.05017  -15.12144 1.000 38.92891 ? 219 ASP A CG  1 
ATOM   1758 O  OD1 . ASP A  1 219 ? -1.95164 22.68377  -15.38517 1.000 38.52577 ? 219 ASP A OD1 1 
ATOM   1759 O  OD2 . ASP A  1 219 ? -4.13639 22.47018  -15.40204 1.000 46.98297 ? 219 ASP A OD2 1 
ATOM   1760 N  N   . PRO A  1 220 ? 0.43584  21.49581  -13.35471 1.000 31.91450 ? 220 PRO A N   1 
ATOM   1761 C  CA  . PRO A  1 220 ? 1.15700  21.69368  -14.62610 1.000 32.91125 ? 220 PRO A CA  1 
ATOM   1762 C  C   . PRO A  1 220 ? 1.77441  20.40964  -15.17364 1.000 35.27026 ? 220 PRO A C   1 
ATOM   1763 O  O   . PRO A  1 220 ? 1.84737  19.39166  -14.48713 1.000 32.14726 ? 220 PRO A O   1 
ATOM   1764 C  CB  . PRO A  1 220 ? 2.24763  22.71815  -14.25827 1.000 30.26614 ? 220 PRO A CB  1 
ATOM   1765 C  CG  . PRO A  1 220 ? 1.79534  23.33947  -12.96281 1.000 33.15104 ? 220 PRO A CG  1 
ATOM   1766 C  CD  . PRO A  1 220 ? 1.07387  22.23687  -12.25682 1.000 29.65377 ? 220 PRO A CD  1 
ATOM   1767 N  N   . SER A  1 221 ? 2.22925  20.44500  -16.42353 1.000 34.62750 ? 221 SER A N   1 
ATOM   1768 C  CA  . SER A  1 221 ? 2.86669  19.30214  -17.05703 1.000 31.79231 ? 221 SER A CA  1 
ATOM   1769 C  C   . SER A  1 221 ? 4.10742  19.77051  -17.79935 1.000 30.41441 ? 221 SER A C   1 
ATOM   1770 O  O   . SER A  1 221 ? 4.08972  20.81606  -18.45506 1.000 24.57223 ? 221 SER A O   1 
ATOM   1771 C  CB  . SER A  1 221 ? 1.91473  18.59126  -18.02576 1.000 32.99023 ? 221 SER A CB  1 
ATOM   1772 O  OG  . SER A  1 221 ? 2.57103  17.52753  -18.69111 1.000 28.39627 ? 221 SER A OG  1 
ATOM   1773 N  N   . ILE A  1 222 ? 5.18340  18.99017  -17.69302 1.000 29.23748 ? 222 ILE A N   1 
ATOM   1774 C  CA  . ILE A  1 222 ? 6.42044  19.32969  -18.38226 1.000 24.21986 ? 222 ILE A CA  1 
ATOM   1775 C  C   . ILE A  1 222 ? 6.23614  19.14516  -19.88274 1.000 21.10060 ? 222 ILE A C   1 
ATOM   1776 O  O   . ILE A  1 222 ? 5.54886  18.21967  -20.33703 1.000 21.73552 ? 222 ILE A O   1 
ATOM   1777 C  CB  . ILE A  1 222 ? 7.58628  18.47941  -17.84609 1.000 22.43529 ? 222 ILE A CB  1 
ATOM   1778 C  CG1 . ILE A  1 222 ? 8.86603  18.75819  -18.63874 1.000 18.86730 ? 222 ILE A CG1 1 
ATOM   1779 C  CG2 . ILE A  1 222 ? 7.23510  16.99962  -17.88250 1.000 21.53261 ? 222 ILE A CG2 1 
ATOM   1780 C  CD1 . ILE A  1 222 ? 10.11736 18.23262  -17.98929 1.000 21.30852 ? 222 ILE A CD1 1 
ATOM   1781 N  N   . VAL A  1 223 ? 6.83366  20.04255  -20.66056 1.000 18.64975 ? 223 VAL A N   1 
ATOM   1782 C  CA  . VAL A  1 223 ? 6.79791  19.96017  -22.11792 1.000 22.99594 ? 223 VAL A CA  1 
ATOM   1783 C  C   . VAL A  1 223 ? 8.09904  19.32429  -22.59657 1.000 23.70420 ? 223 VAL A C   1 
ATOM   1784 O  O   . VAL A  1 223 ? 9.13665  19.45837  -21.93023 1.000 21.77966 ? 223 VAL A O   1 
ATOM   1785 C  CB  . VAL A  1 223 ? 6.57670  21.34468  -22.75007 1.000 21.43625 ? 223 VAL A CB  1 
ATOM   1786 C  CG1 . VAL A  1 223 ? 5.31150  21.98288  -22.19601 1.000 17.50277 ? 223 VAL A CG1 1 
ATOM   1787 C  CG2 . VAL A  1 223 ? 7.77916  22.24546  -22.50944 1.000 16.75751 ? 223 VAL A CG2 1 
ATOM   1788 N  N   . PRO A  1 224 ? 8.09316  18.60746  -23.72338 1.000 21.68771 ? 224 PRO A N   1 
ATOM   1789 C  CA  . PRO A  1 224 ? 9.34805  18.01069  -24.20478 1.000 20.02646 ? 224 PRO A CA  1 
ATOM   1790 C  C   . PRO A  1 224 ? 10.34801 19.04022  -24.68890 1.000 19.82795 ? 224 PRO A C   1 
ATOM   1791 O  O   . PRO A  1 224 ? 11.55404 18.77040  -24.66974 1.000 24.52999 ? 224 PRO A O   1 
ATOM   1792 C  CB  . PRO A  1 224 ? 8.89153  17.09339  -25.34913 1.000 21.05716 ? 224 PRO A CB  1 
ATOM   1793 C  CG  . PRO A  1 224 ? 7.41036  16.94250  -25.17119 1.000 19.59132 ? 224 PRO A CG  1 
ATOM   1794 C  CD  . PRO A  1 224 ? 6.94215  18.21449  -24.54972 1.000 21.72221 ? 224 PRO A CD  1 
ATOM   1795 N  N   . ALA A  1 225 ? 9.88804  20.20882  -25.12696 1.000 19.90224 ? 225 ALA A N   1 
ATOM   1796 C  CA  . ALA A  1 225 ? 10.78469 21.24510  -25.61457 1.000 24.11810 ? 225 ALA A CA  1 
ATOM   1797 C  C   . ALA A  1 225 ? 10.09429 22.59487  -25.50531 1.000 21.95848 ? 225 ALA A C   1 
ATOM   1798 O  O   . ALA A  1 225 ? 8.89231  22.70183  -25.75557 1.000 32.55399 ? 225 ALA A O   1 
ATOM   1799 C  CB  . ALA A  1 225 ? 11.19754 20.98330  -27.06615 1.000 24.19131 ? 225 ALA A CB  1 
ATOM   1800 N  N   . PHE A  1 226 ? 10.86376 23.62007  -25.14826 1.000 24.02969 ? 226 PHE A N   1 
ATOM   1801 C  CA  . PHE A  1 226 ? 10.37271 24.98808  -25.10774 1.000 23.71336 ? 226 PHE A CA  1 
ATOM   1802 C  C   . PHE A  1 226 ? 11.40834 25.91826  -25.71333 1.000 28.77275 ? 226 PHE A C   1 
ATOM   1803 O  O   . PHE A  1 226 ? 12.61270 25.74041  -25.50728 1.000 31.34525 ? 226 PHE A O   1 
ATOM   1804 C  CB  . PHE A  1 226 ? 10.06298 25.43966  -23.67871 1.000 23.64243 ? 226 PHE A CB  1 
ATOM   1805 C  CG  . PHE A  1 226 ? 9.94203  26.92841  -23.53097 1.000 26.14359 ? 226 PHE A CG  1 
ATOM   1806 C  CD1 . PHE A  1 226 ? 8.74110  27.56141  -23.78467 1.000 21.11429 ? 226 PHE A CD1 1 
ATOM   1807 C  CD2 . PHE A  1 226 ? 11.03102 27.69618  -23.14298 1.000 27.17266 ? 226 PHE A CD2 1 
ATOM   1808 C  CE1 . PHE A  1 226 ? 8.61904  28.93119  -23.64765 1.000 23.48446 ? 226 PHE A CE1 1 
ATOM   1809 C  CE2 . PHE A  1 226 ? 10.91715 29.06751  -23.01100 1.000 28.99511 ? 226 PHE A CE2 1 
ATOM   1810 C  CZ  . PHE A  1 226 ? 9.70758  29.68599  -23.26019 1.000 26.87704 ? 226 PHE A CZ  1 
ATOM   1811 N  N   . CYS A  1 227 ? 10.92662 26.92742  -26.43424 1.000 22.66823 ? 227 CYS A N   1 
ATOM   1812 C  CA  . CYS A  1 227 ? 11.78827 27.96394  -26.97854 1.000 34.38246 ? 227 CYS A CA  1 
ATOM   1813 C  C   . CYS A  1 227 ? 10.96909 29.22638  -27.16229 1.000 24.73714 ? 227 CYS A C   1 
ATOM   1814 O  O   . CYS A  1 227 ? 9.83795  29.17353  -27.64985 1.000 23.41703 ? 227 CYS A O   1 
ATOM   1815 C  CB  . CYS A  1 227 ? 12.41085 27.52800  -28.30369 1.000 42.86560 ? 227 CYS A CB  1 
ATOM   1816 S  SG  . CYS A  1 227 ? 11.27561 26.62817  -29.38867 1.000 79.83868 ? 227 CYS A SG  1 
ATOM   1817 N  N   . GLY A  1 228 ? 11.53823 30.35232  -26.75513 1.000 23.06186 ? 228 GLY A N   1 
ATOM   1818 C  CA  . GLY A  1 228 ? 10.81114 31.59662  -26.81213 1.000 22.91917 ? 228 GLY A CA  1 
ATOM   1819 C  C   . GLY A  1 228 ? 10.89365 32.26443  -28.16914 1.000 24.88948 ? 228 GLY A C   1 
ATOM   1820 O  O   . GLY A  1 228 ? 11.73720 31.94376  -29.00589 1.000 33.04245 ? 228 GLY A O   1 
ATOM   1821 N  N   . ASP A  1 229 ? 9.99217  33.22004  -28.38080 1.000 20.43336 ? 229 ASP A N   1 
ATOM   1822 C  CA  . ASP A  1 229 ? 9.93000  33.97424  -29.62513 1.000 18.95855 ? 229 ASP A CA  1 
ATOM   1823 C  C   . ASP A  1 229 ? 10.84549 35.19118  -29.62894 1.000 19.48584 ? 229 ASP A C   1 
ATOM   1824 O  O   . ASP A  1 229 ? 10.95722 35.86086  -30.66089 1.000 24.03717 ? 229 ASP A O   1 
ATOM   1825 C  CB  . ASP A  1 229 ? 8.48447  34.40830  -29.90523 1.000 17.04840 ? 229 ASP A CB  1 
ATOM   1826 C  CG  . ASP A  1 229 ? 7.81759  35.06160  -28.70101 1.000 20.17067 ? 229 ASP A CG  1 
ATOM   1827 O  OD1 . ASP A  1 229 ? 8.52796  35.62484  -27.84075 1.000 18.26332 ? 229 ASP A OD1 1 
ATOM   1828 O  OD2 . ASP A  1 229 ? 6.57241  35.00631  -28.61225 1.000 25.08721 ? 229 ASP A OD2 1 
ATOM   1829 N  N   . THR A  1 230 ? 11.50888 35.48306  -28.51252 1.000 15.76936 ? 230 THR A N   1 
ATOM   1830 C  CA  . THR A  1 230 ? 12.30977 36.68996  -28.36093 1.000 22.76581 ? 230 THR A CA  1 
ATOM   1831 C  C   . THR A  1 230 ? 13.72521 36.30869  -27.95586 1.000 15.53295 ? 230 THR A C   1 
ATOM   1832 O  O   . THR A  1 230 ? 13.91322 35.46733  -27.07308 1.000 15.92406 ? 230 THR A O   1 
ATOM   1833 C  CB  . THR A  1 230 ? 11.69173 37.62347  -27.31536 1.000 20.30344 ? 230 THR A CB  1 
ATOM   1834 O  OG1 . THR A  1 230 ? 10.34607 37.94091  -27.69201 1.000 15.49642 ? 230 THR A OG1 1 
ATOM   1835 C  CG2 . THR A  1 230 ? 12.49173 38.89672  -27.20514 1.000 17.00480 ? 230 THR A CG2 1 
ATOM   1836 N  N   . ILE A  1 231 ? 14.71403 36.92881  -28.59516 1.000 15.78285 ? 231 ILE A N   1 
ATOM   1837 C  CA  . ILE A  1 231 ? 16.12178 36.63662  -28.34971 1.000 16.17211 ? 231 ILE A CA  1 
ATOM   1838 C  C   . ILE A  1 231 ? 16.70575 37.72456  -27.46050 1.000 16.88672 ? 231 ILE A C   1 
ATOM   1839 O  O   . ILE A  1 231 ? 16.50803 38.91997  -27.71356 1.000 18.09201 ? 231 ILE A O   1 
ATOM   1840 C  CB  . ILE A  1 231 ? 16.90599 36.52611  -29.66801 1.000 16.11500 ? 231 ILE A CB  1 
ATOM   1841 C  CG1 . ILE A  1 231 ? 16.31516 35.42218  -30.54648 1.000 19.08882 ? 231 ILE A CG1 1 
ATOM   1842 C  CG2 . ILE A  1 231 ? 18.37699 36.25581  -29.39018 1.000 15.31024 ? 231 ILE A CG2 1 
ATOM   1843 C  CD1 . ILE A  1 231 ? 16.33854 34.05702  -29.90029 1.000 14.84730 ? 231 ILE A CD1 1 
ATOM   1844 N  N   . LEU A  1 232 ? 17.42925 37.31189  -26.42274 1.000 20.72324 ? 232 LEU A N   1 
ATOM   1845 C  CA  . LEU A  1 232 ? 18.09106 38.22340  -25.50335 1.000 17.46733 ? 232 LEU A CA  1 
ATOM   1846 C  C   . LEU A  1 232 ? 19.59337 37.98047  -25.52848 1.000 20.24797 ? 232 LEU A C   1 
ATOM   1847 O  O   . LEU A  1 232 ? 20.05390 36.86209  -25.77712 1.000 24.56388 ? 232 LEU A O   1 
ATOM   1848 C  CB  . LEU A  1 232 ? 17.57317 38.05737  -24.06476 1.000 16.45614 ? 232 LEU A CB  1 
ATOM   1849 C  CG  . LEU A  1 232 ? 16.16291 38.53338  -23.70078 1.000 17.75055 ? 232 LEU A CG  1 
ATOM   1850 C  CD1 . LEU A  1 232 ? 15.08559 37.61686  -24.26427 1.000 15.59340 ? 232 LEU A CD1 1 
ATOM   1851 C  CD2 . LEU A  1 232 ? 16.02449 38.65332  -22.19129 1.000 16.26016 ? 232 LEU A CD2 1 
ATOM   1852 N  N   . VAL A  1 233 ? 20.35571 39.04245  -25.27715 1.000 20.29326 ? 233 VAL A N   1 
ATOM   1853 C  CA  . VAL A  1 233 ? 21.80229 38.95894  -25.10530 1.000 17.57886 ? 233 VAL A CA  1 
ATOM   1854 C  C   . VAL A  1 233 ? 22.15871 39.72989  -23.84393 1.000 17.43140 ? 233 VAL A C   1 
ATOM   1855 O  O   . VAL A  1 233 ? 21.86271 40.92698  -23.74313 1.000 12.93424 ? 233 VAL A O   1 
ATOM   1856 C  CB  . VAL A  1 233 ? 22.57497 39.51670  -26.31216 1.000 14.14058 ? 233 VAL A CB  1 
ATOM   1857 C  CG1 . VAL A  1 233 ? 24.06584 39.26723  -26.14034 1.000 14.63497 ? 233 VAL A CG1 1 
ATOM   1858 C  CG2 . VAL A  1 233 ? 22.07527 38.89973  -27.60236 1.000 14.06990 ? 233 VAL A CG2 1 
ATOM   1859 N  N   . ASN A  1 234 ? 22.79051 39.04630  -22.88738 1.000 21.51901 ? 234 ASN A N   1 
ATOM   1860 C  CA  . ASN A  1 234 ? 23.14934 39.63706  -21.59640 1.000 18.51596 ? 234 ASN A CA  1 
ATOM   1861 C  C   . ASN A  1 234 ? 21.92746 40.23677  -20.90503 1.000 18.72421 ? 234 ASN A C   1 
ATOM   1862 O  O   . ASN A  1 234 ? 21.99625 41.29538  -20.27714 1.000 19.23045 ? 234 ASN A O   1 
ATOM   1863 C  CB  . ASN A  1 234 ? 24.25504 40.68191  -21.75205 1.000 12.69574 ? 234 ASN A CB  1 
ATOM   1864 C  CG  . ASN A  1 234 ? 25.55717 40.08548  -22.25173 1.000 14.93807 ? 234 ASN A CG  1 
ATOM   1865 O  OD1 . ASN A  1 234 ? 25.74349 38.86960  -22.23350 1.000 19.60737 ? 234 ASN A OD1 1 
ATOM   1866 N  ND2 . ASN A  1 234 ? 26.47070 40.94279  -22.69235 1.000 12.67183 ? 234 ASN A ND2 1 
ATOM   1867 N  N   . GLY A  1 235 ? 20.79362 39.55199  -21.03025 1.000 20.13247 ? 235 GLY A N   1 
ATOM   1868 C  CA  . GLY A  1 235 ? 19.58121 39.97667  -20.35773 1.000 19.18866 ? 235 GLY A CA  1 
ATOM   1869 C  C   . GLY A  1 235 ? 18.88631 41.16550  -20.98043 1.000 19.50023 ? 235 GLY A C   1 
ATOM   1870 O  O   . GLY A  1 235 ? 18.16257 41.88392  -20.28403 1.000 24.52449 ? 235 GLY A O   1 
ATOM   1871 N  N   . LYS A  1 236 ? 19.07967 41.39611  -22.27685 1.000 19.35723 ? 236 LYS A N   1 
ATOM   1872 C  CA  . LYS A  1 236 ? 18.44763 42.51093  -22.96759 1.000 14.00301 ? 236 LYS A CA  1 
ATOM   1873 C  C   . LYS A  1 236 ? 17.86629 42.02659  -24.28622 1.000 12.87246 ? 236 LYS A C   1 
ATOM   1874 O  O   . LYS A  1 236 ? 18.55502 41.36345  -25.06752 1.000 15.17368 ? 236 LYS A O   1 
ATOM   1875 C  CB  . LYS A  1 236 ? 19.44178 43.64750  -23.21142 1.000 14.04348 ? 236 LYS A CB  1 
ATOM   1876 C  CG  . LYS A  1 236 ? 18.84029 45.02853  -23.02881 1.000 19.40040 ? 236 LYS A CG  1 
ATOM   1877 C  CD  . LYS A  1 236 ? 18.26066 45.18803  -21.63032 1.000 23.53533 ? 236 LYS A CD  1 
ATOM   1878 C  CE  . LYS A  1 236 ? 17.67729 46.57450  -21.41974 1.000 23.52946 ? 236 LYS A CE  1 
ATOM   1879 N  NZ  . LYS A  1 236 ? 17.12215 46.73895  -20.04672 1.000 24.89871 ? 236 LYS A NZ  1 
ATOM   1880 N  N   . VAL A  1 237 ? 16.60404 42.37094  -24.53094 1.000 13.77220 ? 237 VAL A N   1 
ATOM   1881 C  CA  . VAL A  1 237 ? 15.90855 41.94456  -25.74035 1.000 18.67171 ? 237 VAL A CA  1 
ATOM   1882 C  C   . VAL A  1 237 ? 16.50371 42.66090  -26.94634 1.000 17.35881 ? 237 VAL A C   1 
ATOM   1883 O  O   . VAL A  1 237 ? 16.52330 43.89652  -26.99892 1.000 16.01247 ? 237 VAL A O   1 
ATOM   1884 C  CB  . VAL A  1 237 ? 14.40440 42.21652  -25.62365 1.000 19.46136 ? 237 VAL A CB  1 
ATOM   1885 C  CG1 . VAL A  1 237 ? 13.75277 42.16257  -26.98897 1.000 17.46697 ? 237 VAL A CG1 1 
ATOM   1886 C  CG2 . VAL A  1 237 ? 13.75682 41.21945  -24.67593 1.000 20.16063 ? 237 VAL A CG2 1 
ATOM   1887 N  N   . TRP A  1 238 ? 16.97489 41.87630  -27.93125 1.000 17.09233 ? 238 TRP A N   1 
ATOM   1888 C  CA  . TRP A  1 238 ? 17.58285 42.32668  -29.18416 1.000 17.94529 ? 238 TRP A CA  1 
ATOM   1889 C  C   . TRP A  1 238 ? 18.36793 43.62016  -29.00208 1.000 17.57982 ? 238 TRP A C   1 
ATOM   1890 O  O   . TRP A  1 238 ? 18.00706 44.64789  -29.58835 1.000 15.27415 ? 238 TRP A O   1 
ATOM   1891 C  CB  . TRP A  1 238 ? 16.51699 42.52276  -30.26660 1.000 13.54757 ? 238 TRP A CB  1 
ATOM   1892 C  CG  . TRP A  1 238 ? 15.86252 41.25367  -30.72521 1.000 19.12915 ? 238 TRP A CG  1 
ATOM   1893 C  CD1 . TRP A  1 238 ? 16.48207 40.14901  -31.23620 1.000 20.34678 ? 238 TRP A CD1 1 
ATOM   1894 C  CD2 . TRP A  1 238 ? 14.45766 40.96681  -30.73805 1.000 20.15402 ? 238 TRP A CD2 1 
ATOM   1895 N  NE1 . TRP A  1 238 ? 15.55148 39.18827  -31.55346 1.000 20.26905 ? 238 TRP A NE1 1 
ATOM   1896 C  CE2 . TRP A  1 238 ? 14.30134 39.66627  -31.25886 1.000 22.05321 ? 238 TRP A CE2 1 
ATOM   1897 C  CE3 . TRP A  1 238 ? 13.31791 41.68175  -30.35718 1.000 18.70239 ? 238 TRP A CE3 1 
ATOM   1898 C  CZ2 . TRP A  1 238 ? 13.05089 39.06598  -31.40603 1.000 20.76281 ? 238 TRP A CZ2 1 
ATOM   1899 C  CZ3 . TRP A  1 238 ? 12.07854 41.08341  -30.50167 1.000 20.48743 ? 238 TRP A CZ3 1 
ATOM   1900 C  CH2 . TRP A  1 238 ? 11.95498 39.78928  -31.02312 1.000 21.93636 ? 238 TRP A CH2 1 
ATOM   1901 N  N   . PRO A  1 239 ? 19.43287 43.61806  -28.21232 1.000 18.88953 ? 239 PRO A N   1 
ATOM   1902 C  CA  . PRO A  1 239 ? 20.11858 44.86673  -27.87390 1.000 17.38653 ? 239 PRO A CA  1 
ATOM   1903 C  C   . PRO A  1 239 ? 20.97751 45.34964  -29.03727 1.000 17.26510 ? 239 PRO A C   1 
ATOM   1904 O  O   . PRO A  1 239 ? 21.01596 44.75038  -30.10964 1.000 20.49899 ? 239 PRO A O   1 
ATOM   1905 C  CB  . PRO A  1 239 ? 20.97280 44.47146  -26.67013 1.000 15.92208 ? 239 PRO A CB  1 
ATOM   1906 C  CG  . PRO A  1 239 ? 21.31102 43.04264  -26.93299 1.000 16.76803 ? 239 PRO A CG  1 
ATOM   1907 C  CD  . PRO A  1 239 ? 20.11646 42.44411  -27.63965 1.000 15.57710 ? 239 PRO A CD  1 
ATOM   1908 N  N   . TYR A  1 240 ? 21.66748 46.46394  -28.80621 1.000 18.64137 ? 240 TYR A N   1 
ATOM   1909 C  CA  . TYR A  1 240 ? 22.64069 46.97349  -29.75835 1.000 22.07694 ? 240 TYR A CA  1 
ATOM   1910 C  C   . TYR A  1 240 ? 23.87869 47.42985  -29.00112 1.000 24.47765 ? 240 TYR A C   1 
ATOM   1911 O  O   . TYR A  1 240 ? 23.84832 47.64092  -27.78635 1.000 21.49622 ? 240 TYR A O   1 
ATOM   1912 C  CB  . TYR A  1 240 ? 22.07257 48.11891  -30.61384 1.000 22.17310 ? 240 TYR A CB  1 
ATOM   1913 C  CG  . TYR A  1 240 ? 22.00089 49.46009  -29.91827 1.000 22.01055 ? 240 TYR A CG  1 
ATOM   1914 C  CD1 . TYR A  1 240 ? 20.87499 49.82968  -29.19543 1.000 24.26708 ? 240 TYR A CD1 1 
ATOM   1915 C  CD2 . TYR A  1 240 ? 23.05290 50.36533  -30.00060 1.000 22.94617 ? 240 TYR A CD2 1 
ATOM   1916 C  CE1 . TYR A  1 240 ? 20.80358 51.05577  -28.56199 1.000 20.26327 ? 240 TYR A CE1 1 
ATOM   1917 C  CE2 . TYR A  1 240 ? 22.99161 51.59145  -29.36946 1.000 24.17682 ? 240 TYR A CE2 1 
ATOM   1918 C  CZ  . TYR A  1 240 ? 21.86350 51.93304  -28.65499 1.000 22.99927 ? 240 TYR A CZ  1 
ATOM   1919 O  OH  . TYR A  1 240 ? 21.79750 53.15536  -28.02604 1.000 28.75298 ? 240 TYR A OH  1 
ATOM   1920 N  N   . ASP A  1 241 ? 24.97579 47.57964  -29.73794 1.000 20.32178 ? 241 ASP A N   1 
ATOM   1921 C  CA  . ASP A  1 241 ? 26.24337 47.97308  -29.14474 1.000 15.84621 ? 241 ASP A CA  1 
ATOM   1922 C  C   . ASP A  1 241 ? 27.01412 48.81247  -30.15148 1.000 24.16360 ? 241 ASP A C   1 
ATOM   1923 O  O   . ASP A  1 241 ? 27.04287 48.49374  -31.34344 1.000 23.49044 ? 241 ASP A O   1 
ATOM   1924 C  CB  . ASP A  1 241 ? 27.06360 46.74707  -28.72497 1.000 20.93878 ? 241 ASP A CB  1 
ATOM   1925 C  CG  . ASP A  1 241 ? 28.14245 47.08198  -27.71291 1.000 18.05142 ? 241 ASP A CG  1 
ATOM   1926 O  OD1 . ASP A  1 241 ? 28.19606 48.24278  -27.25771 1.000 22.29102 ? 241 ASP A OD1 1 
ATOM   1927 O  OD2 . ASP A  1 241 ? 28.93602 46.18078  -27.36941 1.000 19.04553 ? 241 ASP A OD2 1 
ATOM   1928 N  N   . GLU A  1 242 ? 27.62869 49.88660  -29.66623 1.000 24.04489 ? 242 GLU A N   1 
ATOM   1929 C  CA  . GLU A  1 242 ? 28.42702 50.77839  -30.49617 1.000 22.79600 ? 242 GLU A CA  1 
ATOM   1930 C  C   . GLU A  1 242 ? 29.90029 50.44295  -30.30326 1.000 22.57246 ? 242 GLU A C   1 
ATOM   1931 O  O   . GLU A  1 242 ? 30.42957 50.56831  -29.19358 1.000 26.10187 ? 242 GLU A O   1 
ATOM   1932 C  CB  . GLU A  1 242 ? 28.14616 52.23975  -30.14841 1.000 28.24187 ? 242 GLU A CB  1 
ATOM   1933 C  CG  . GLU A  1 242 ? 26.75008 52.69974  -30.54261 1.000 32.80852 ? 242 GLU A CG  1 
ATOM   1934 C  CD  . GLU A  1 242 ? 26.40444 54.06837  -29.99183 1.000 40.20398 ? 242 GLU A CD  1 
ATOM   1935 O  OE1 . GLU A  1 242 ? 26.85332 54.39095  -28.87170 1.000 41.91291 ? 242 GLU A OE1 1 
ATOM   1936 O  OE2 . GLU A  1 242 ? 25.68518 54.82235  -30.68093 1.000 41.72710 ? 242 GLU A OE2 1 
ATOM   1937 N  N   . LEU A  1 243 ? 30.55460 50.01592  -31.37873 1.000 22.44517 ? 243 LEU A N   1 
ATOM   1938 C  CA  . LEU A  1 243 ? 31.93508 49.56207  -31.33346 1.000 21.60804 ? 243 LEU A CA  1 
ATOM   1939 C  C   . LEU A  1 243 ? 32.82186 50.47539  -32.16914 1.000 24.54006 ? 243 LEU A C   1 
ATOM   1940 O  O   . LEU A  1 243 ? 32.34940 51.33071  -32.92221 1.000 27.87437 ? 243 LEU A O   1 
ATOM   1941 C  CB  . LEU A  1 243 ? 32.05720 48.11732  -31.83332 1.000 21.50925 ? 243 LEU A CB  1 
ATOM   1942 C  CG  . LEU A  1 243 ? 31.17430 47.06848  -31.15920 1.000 22.45076 ? 243 LEU A CG  1 
ATOM   1943 C  CD1 . LEU A  1 243 ? 31.53403 45.67993  -31.66459 1.000 26.88778 ? 243 LEU A CD1 1 
ATOM   1944 C  CD2 . LEU A  1 243 ? 31.30271 47.14706  -29.64570 1.000 23.15252 ? 243 LEU A CD2 1 
ATOM   1945 N  N   . GLU A  1 244 ? 34.12937 50.27451  -32.02403 1.000 26.24118 ? 244 GLU A N   1 
ATOM   1946 C  CA  . GLU A  1 244 ? 35.20165 50.92921  -32.75027 1.000 24.50087 ? 244 GLU A CA  1 
ATOM   1947 C  C   . GLU A  1 244 ? 35.68447 50.04041  -33.89066 1.000 31.91898 ? 244 GLU A C   1 
ATOM   1948 O  O   . GLU A  1 244 ? 35.66003 48.81023  -33.77979 1.000 27.91611 ? 244 GLU A O   1 
ATOM   1949 C  CB  . GLU A  1 244 ? 36.37499 51.24036  -31.81598 1.000 24.88395 ? 244 GLU A CB  1 
ATOM   1950 C  CG  . GLU A  1 244 ? 35.98349 51.99104  -30.55348 1.000 21.75281 ? 244 GLU A CG  1 
ATOM   1951 C  CD  . GLU A  1 244 ? 37.13235 52.11630  -29.57207 1.000 30.79515 ? 244 GLU A CD  1 
ATOM   1952 O  OE1 . GLU A  1 244 ? 38.30085 51.99082  -29.99991 1.000 25.74973 ? 244 GLU A OE1 1 
ATOM   1953 O  OE2 . GLU A  1 244 ? 36.86608 52.33336  -28.37041 1.000 33.24590 ? 244 GLU A OE2 1 
ATOM   1954 N  N   . PRO A  1 245 ? 36.12380 50.62845  -35.00652 1.000 30.18626 ? 245 PRO A N   1 
ATOM   1955 C  CA  . PRO A  1 245 ? 36.59098 49.80809  -36.13300 1.000 25.61512 ? 245 PRO A CA  1 
ATOM   1956 C  C   . PRO A  1 245 ? 37.91381 49.11772  -35.84131 1.000 24.26315 ? 245 PRO A C   1 
ATOM   1957 O  O   . PRO A  1 245 ? 38.96951 49.56374  -36.30155 1.000 26.26268 ? 245 PRO A O   1 
ATOM   1958 C  CB  . PRO A  1 245 ? 36.72485 50.82538  -37.27269 1.000 27.30828 ? 245 PRO A CB  1 
ATOM   1959 C  CG  . PRO A  1 245 ? 36.97576 52.12248  -36.58200 1.000 26.66367 ? 245 PRO A CG  1 
ATOM   1960 C  CD  . PRO A  1 245 ? 36.18000 52.06953  -35.30742 1.000 25.80341 ? 245 PRO A CD  1 
ATOM   1961 N  N   . ARG A  1 246 ? 37.86779 48.02650  -35.08267 1.000 23.47054 ? 246 ARG A N   1 
ATOM   1962 C  CA  . ARG A  1 246 ? 39.07142 47.29903  -34.70185 1.000 22.47736 ? 246 ARG A CA  1 
ATOM   1963 C  C   . ARG A  1 246 ? 38.69630 45.84865  -34.41495 1.000 25.80950 ? 246 ARG A C   1 
ATOM   1964 O  O   . ARG A  1 246 ? 37.59288 45.39718  -34.73712 1.000 23.68973 ? 246 ARG A O   1 
ATOM   1965 C  CB  . ARG A  1 246 ? 39.74622 47.96590  -33.49765 1.000 20.97890 ? 246 ARG A CB  1 
ATOM   1966 C  CG  . ARG A  1 246 ? 38.81513 48.21261  -32.32514 1.000 19.37247 ? 246 ARG A CG  1 
ATOM   1967 C  CD  . ARG A  1 246 ? 39.59703 48.32628  -31.03351 1.000 22.97101 ? 246 ARG A CD  1 
ATOM   1968 N  NE  . ARG A  1 246 ? 40.21349 47.05608  -30.66962 1.000 26.60129 ? 246 ARG A NE  1 
ATOM   1969 C  CZ  . ARG A  1 246 ? 41.09943 46.90443  -29.69468 1.000 29.63284 ? 246 ARG A CZ  1 
ATOM   1970 N  NH1 . ARG A  1 246 ? 41.51560 47.93258  -28.97294 1.000 27.17866 ? 246 ARG A NH1 1 
ATOM   1971 N  NH2 . ARG A  1 246 ? 41.58283 45.69132  -29.44001 1.000 21.71729 ? 246 ARG A NH2 1 
ATOM   1972 N  N   . LYS A  1 247 ? 39.62384 45.11647  -33.80176 1.000 25.90126 ? 247 LYS A N   1 
ATOM   1973 C  CA  . LYS A  1 247 ? 39.41133 43.71633  -33.46132 1.000 25.09043 ? 247 LYS A CA  1 
ATOM   1974 C  C   . LYS A  1 247 ? 38.77557 43.60305  -32.08135 1.000 25.73265 ? 247 LYS A C   1 
ATOM   1975 O  O   . LYS A  1 247 ? 39.21358 44.25965  -31.13072 1.000 25.39588 ? 247 LYS A O   1 
ATOM   1976 C  CB  . LYS A  1 247 ? 40.73022 42.94172  -33.49661 1.000 26.37229 ? 247 LYS A CB  1 
ATOM   1977 C  CG  . LYS A  1 247 ? 41.27425 42.68241  -34.89336 1.000 21.16747 ? 247 LYS A CG  1 
ATOM   1978 C  CD  . LYS A  1 247 ? 42.54455 41.84414  -34.83910 1.000 25.43918 ? 247 LYS A CD  1 
ATOM   1979 C  CE  . LYS A  1 247 ? 43.74034 42.65905  -34.36294 1.000 30.74070 ? 247 LYS A CE  1 
ATOM   1980 N  NZ  . LYS A  1 247 ? 44.26253 43.56335  -35.42780 1.000 31.49484 ? 247 LYS A NZ  1 
ATOM   1981 N  N   . TYR A  1 248 ? 37.74399 42.77037  -31.97960 1.000 18.02716 ? 248 TYR A N   1 
ATOM   1982 C  CA  . TYR A  1 248 ? 37.07688 42.47949  -30.72202 1.000 16.47984 ? 248 TYR A CA  1 
ATOM   1983 C  C   . TYR A  1 248 ? 37.17368 40.98953  -30.42372 1.000 18.78673 ? 248 TYR A C   1 
ATOM   1984 O  O   . TYR A  1 248 ? 37.43354 40.17081  -31.30981 1.000 18.40239 ? 248 TYR A O   1 
ATOM   1985 C  CB  . TYR A  1 248 ? 35.60259 42.90721  -30.75520 1.000 18.14876 ? 248 TYR A CB  1 
ATOM   1986 C  CG  . TYR A  1 248 ? 35.37094 44.37571  -30.48202 1.000 22.01317 ? 248 TYR A CG  1 
ATOM   1987 C  CD1 . TYR A  1 248 ? 35.56897 45.32743  -31.47336 1.000 20.54710 ? 248 TYR A CD1 1 
ATOM   1988 C  CD2 . TYR A  1 248 ? 34.94473 44.80908  -29.23259 1.000 18.87309 ? 248 TYR A CD2 1 
ATOM   1989 C  CE1 . TYR A  1 248 ? 35.35580 46.67064  -31.22629 1.000 24.80651 ? 248 TYR A CE1 1 
ATOM   1990 C  CE2 . TYR A  1 248 ? 34.72926 46.14783  -28.97604 1.000 19.75042 ? 248 TYR A CE2 1 
ATOM   1991 C  CZ  . TYR A  1 248 ? 34.93553 47.07519  -29.97637 1.000 28.00038 ? 248 TYR A CZ  1 
ATOM   1992 O  OH  . TYR A  1 248 ? 34.72065 48.41163  -29.72586 1.000 25.49432 ? 248 TYR A OH  1 
ATOM   1993 N  N   . ARG A  1 249 ? 36.96321 40.64651  -29.15610 1.000 19.89523 ? 249 ARG A N   1 
ATOM   1994 C  CA  . ARG A  1 249 ? 36.91940 39.26146  -28.70452 1.000 17.78007 ? 249 ARG A CA  1 
ATOM   1995 C  C   . ARG A  1 249 ? 35.55449 39.00691  -28.08584 1.000 17.99318 ? 249 ARG A C   1 
ATOM   1996 O  O   . ARG A  1 249 ? 35.20137 39.63182  -27.08014 1.000 19.22083 ? 249 ARG A O   1 
ATOM   1997 C  CB  . ARG A  1 249 ? 38.03046 38.96882  -27.69413 1.000 16.96188 ? 249 ARG A CB  1 
ATOM   1998 C  CG  . ARG A  1 249 ? 38.05851 37.52705  -27.21194 1.000 16.21222 ? 249 ARG A CG  1 
ATOM   1999 C  CD  . ARG A  1 249 ? 39.07969 37.33129  -26.10410 1.000 16.28727 ? 249 ARG A CD  1 
ATOM   2000 N  NE  . ARG A  1 249 ? 39.24172 35.92660  -25.74713 1.000 14.39921 ? 249 ARG A NE  1 
ATOM   2001 C  CZ  . ARG A  1 249 ? 39.94827 35.49467  -24.71126 1.000 18.21615 ? 249 ARG A CZ  1 
ATOM   2002 N  NH1 . ARG A  1 249 ? 40.56055 36.33529  -23.89320 1.000 21.74913 ? 249 ARG A NH1 1 
ATOM   2003 N  NH2 . ARG A  1 249 ? 40.04016 34.18688  -24.48808 1.000 14.18941 ? 249 ARG A NH2 1 
ATOM   2004 N  N   . PHE A  1 250 ? 34.78923 38.10055  -28.68611 1.000 17.49052 ? 250 PHE A N   1 
ATOM   2005 C  CA  . PHE A  1 250 ? 33.45352 37.76300  -28.21136 1.000 15.63005 ? 250 PHE A CA  1 
ATOM   2006 C  C   . PHE A  1 250 ? 33.49312 36.40412  -27.52652 1.000 15.23185 ? 250 PHE A C   1 
ATOM   2007 O  O   . PHE A  1 250 ? 33.88831 35.40661  -28.13912 1.000 18.34922 ? 250 PHE A O   1 
ATOM   2008 C  CB  . PHE A  1 250 ? 32.44268 37.75734  -29.35792 1.000 17.57713 ? 250 PHE A CB  1 
ATOM   2009 C  CG  . PHE A  1 250 ? 32.23612 39.10247  -29.99179 1.000 17.51966 ? 250 PHE A CG  1 
ATOM   2010 C  CD1 . PHE A  1 250 ? 31.43901 40.05547  -29.38086 1.000 23.10510 ? 250 PHE A CD1 1 
ATOM   2011 C  CD2 . PHE A  1 250 ? 32.83366 39.41223  -31.20181 1.000 22.70944 ? 250 PHE A CD2 1 
ATOM   2012 C  CE1 . PHE A  1 250 ? 31.24482 41.29569  -29.96317 1.000 23.02241 ? 250 PHE A CE1 1 
ATOM   2013 C  CE2 . PHE A  1 250 ? 32.64381 40.65051  -31.78984 1.000 22.61543 ? 250 PHE A CE2 1 
ATOM   2014 C  CZ  . PHE A  1 250 ? 31.84765 41.59247  -31.16942 1.000 22.45148 ? 250 PHE A CZ  1 
ATOM   2015 N  N   . ARG A  1 251 ? 33.09109 36.37196  -26.25845 1.000 16.98446 ? 251 ARG A N   1 
ATOM   2016 C  CA  . ARG A  1 251 ? 32.94721 35.13046  -25.50046 1.000 15.42727 ? 251 ARG A CA  1 
ATOM   2017 C  C   . ARG A  1 251 ? 31.46932 34.75902  -25.55452 1.000 15.86343 ? 251 ARG A C   1 
ATOM   2018 O  O   . ARG A  1 251 ? 30.66909 35.19494  -24.72603 1.000 14.26540 ? 251 ARG A O   1 
ATOM   2019 C  CB  . ARG A  1 251 ? 33.44049 35.30273  -24.06869 1.000 21.11785 ? 251 ARG A CB  1 
ATOM   2020 C  CG  . ARG A  1 251 ? 34.74904 36.06813  -23.95012 1.000 17.94394 ? 251 ARG A CG  1 
ATOM   2021 C  CD  . ARG A  1 251 ? 35.89150 35.33426  -24.63196 1.000 14.07940 ? 251 ARG A CD  1 
ATOM   2022 N  NE  . ARG A  1 251 ? 36.24596 34.10218  -23.93747 1.000 15.55219 ? 251 ARG A NE  1 
ATOM   2023 C  CZ  . ARG A  1 251 ? 37.10931 34.03039  -22.93352 1.000 13.90708 ? 251 ARG A CZ  1 
ATOM   2024 N  NH1 . ARG A  1 251 ? 37.72269 35.10713  -22.47088 1.000 14.38882 ? 251 ARG A NH1 1 
ATOM   2025 N  NH2 . ARG A  1 251 ? 37.36313 32.84870  -22.37928 1.000 13.47695 ? 251 ARG A NH2 1 
ATOM   2026 N  N   . ILE A  1 252 ? 31.10654 33.95150  -26.54828 1.000 17.45785 ? 252 ILE A N   1 
ATOM   2027 C  CA  . ILE A  1 252 ? 29.71045 33.64012  -26.83456 1.000 14.35995 ? 252 ILE A CA  1 
ATOM   2028 C  C   . ILE A  1 252 ? 29.28124 32.42101  -26.03254 1.000 14.40724 ? 252 ILE A C   1 
ATOM   2029 O  O   . ILE A  1 252 ? 30.00512 31.42179  -25.95193 1.000 14.98535 ? 252 ILE A O   1 
ATOM   2030 C  CB  . ILE A  1 252 ? 29.50105 33.41405  -28.34324 1.000 13.84909 ? 252 ILE A CB  1 
ATOM   2031 C  CG1 . ILE A  1 252 ? 29.96174 34.63972  -29.13443 1.000 17.65668 ? 252 ILE A CG1 1 
ATOM   2032 C  CG2 . ILE A  1 252 ? 28.04151 33.11205  -28.64078 1.000 11.10182 ? 252 ILE A CG2 1 
ATOM   2033 C  CD1 . ILE A  1 252 ? 29.64924 34.56186  -30.61141 1.000 10.52690 ? 252 ILE A CD1 1 
ATOM   2034 N  N   . LEU A  1 253 ? 28.09107 32.50208  -25.44021 1.000 13.91886 ? 253 LEU A N   1 
ATOM   2035 C  CA  . LEU A  1 253 ? 27.50850 31.39854  -24.68922 1.000 12.96979 ? 253 LEU A CA  1 
ATOM   2036 C  C   . LEU A  1 253 ? 26.03479 31.28081  -25.03935 1.000 14.77181 ? 253 LEU A C   1 
ATOM   2037 O  O   . LEU A  1 253 ? 25.31878 32.28594  -25.05802 1.000 17.73380 ? 253 LEU A O   1 
ATOM   2038 C  CB  . LEU A  1 253 ? 27.67047 31.60284  -23.17822 1.000 12.66641 ? 253 LEU A CB  1 
ATOM   2039 C  CG  . LEU A  1 253 ? 26.75993 30.74743  -22.29132 1.000 12.84604 ? 253 LEU A CG  1 
ATOM   2040 C  CD1 . LEU A  1 253 ? 27.13021 29.27133  -22.37981 1.000 11.13211 ? 253 LEU A CD1 1 
ATOM   2041 C  CD2 . LEU A  1 253 ? 26.78841 31.23111  -20.84910 1.000 11.39597 ? 253 LEU A CD2 1 
ATOM   2042 N  N   . ASN A  1 254 ? 25.58641 30.05831  -25.31647 1.000 18.77225 ? 254 ASN A N   1 
ATOM   2043 C  CA  . ASN A  1 254 ? 24.17163 29.76702  -25.52053 1.000 17.04737 ? 254 ASN A CA  1 
ATOM   2044 C  C   . ASN A  1 254 ? 23.61719 29.19612  -24.22065 1.000 16.55273 ? 254 ASN A C   1 
ATOM   2045 O  O   . ASN A  1 254 ? 23.88437 28.03959  -23.87802 1.000 14.36371 ? 254 ASN A O   1 
ATOM   2046 C  CB  . ASN A  1 254 ? 23.96691 28.79694  -26.68218 1.000 15.84575 ? 254 ASN A CB  1 
ATOM   2047 C  CG  . ASN A  1 254 ? 22.50059 28.47581  -26.92472 1.000 15.99332 ? 254 ASN A CG  1 
ATOM   2048 O  OD1 . ASN A  1 254 ? 21.61129 29.08385  -26.32797 1.000 20.28736 ? 254 ASN A OD1 1 
ATOM   2049 N  ND2 . ASN A  1 254 ? 22.24286 27.52175  -27.81114 1.000 9.73823  ? 254 ASN A ND2 1 
ATOM   2050 N  N   . ALA A  1 255 ? 22.84805 30.01021  -23.49842 1.000 19.25440 ? 255 ALA A N   1 
ATOM   2051 C  CA  . ALA A  1 255 ? 22.24420 29.61061  -22.23404 1.000 16.65066 ? 255 ALA A CA  1 
ATOM   2052 C  C   . ALA A  1 255 ? 20.73193 29.44316  -22.35550 1.000 17.56589 ? 255 ALA A C   1 
ATOM   2053 O  O   . ALA A  1 255 ? 19.99552 29.66564  -21.39158 1.000 15.29269 ? 255 ALA A O   1 
ATOM   2054 C  CB  . ALA A  1 255 ? 22.58717 30.61503  -21.13576 1.000 12.69016 ? 255 ALA A CB  1 
ATOM   2055 N  N   . SER A  1 256 ? 20.25902 29.05833  -23.53843 1.000 17.86075 ? 256 SER A N   1 
ATOM   2056 C  CA  . SER A  1 256 ? 18.85073 28.75785  -23.73073 1.000 11.18493 ? 256 SER A CA  1 
ATOM   2057 C  C   . SER A  1 256 ? 18.50212 27.41667  -23.08919 1.000 15.28933 ? 256 SER A C   1 
ATOM   2058 O  O   . SER A  1 256 ? 19.37245 26.62059  -22.72418 1.000 15.09795 ? 256 SER A O   1 
ATOM   2059 C  CB  . SER A  1 256 ? 18.50610 28.72660  -25.21945 1.000 13.57564 ? 256 SER A CB  1 
ATOM   2060 O  OG  . SER A  1 256 ? 18.71838 29.98895  -25.82608 1.000 22.42013 ? 256 SER A OG  1 
ATOM   2061 N  N   . ASN A  1 257 ? 17.19891 27.16632  -22.95894 1.000 15.25014 ? 257 ASN A N   1 
ATOM   2062 C  CA  . ASN A  1 257 ? 16.74752 25.87171  -22.46645 1.000 14.09515 ? 257 ASN A CA  1 
ATOM   2063 C  C   . ASN A  1 257 ? 16.81865 24.79439  -23.54154 1.000 17.77759 ? 257 ASN A C   1 
ATOM   2064 O  O   . ASN A  1 257 ? 17.03478 23.62090  -23.21951 1.000 18.42550 ? 257 ASN A O   1 
ATOM   2065 C  CB  . ASN A  1 257 ? 15.31786 25.97618  -21.93075 1.000 18.10198 ? 257 ASN A CB  1 
ATOM   2066 C  CG  . ASN A  1 257 ? 15.23401 26.75679  -20.63199 1.000 21.84653 ? 257 ASN A CG  1 
ATOM   2067 O  OD1 . ASN A  1 257 ? 16.11799 27.55247  -20.31274 1.000 21.69119 ? 257 ASN A OD1 1 
ATOM   2068 N  ND2 . ASN A  1 257 ? 14.16610 26.52949  -19.87336 1.000 16.39223 ? 257 ASN A ND2 1 
ATOM   2069 N  N   . THR A  1 258 ? 16.65731 25.16745  -24.81237 1.000 15.30080 ? 258 THR A N   1 
ATOM   2070 C  CA  . THR A  1 258 ? 16.51407 24.18635  -25.88198 1.000 14.46888 ? 258 THR A CA  1 
ATOM   2071 C  C   . THR A  1 258 ? 17.11749 24.67151  -27.19474 1.000 17.22895 ? 258 THR A C   1 
ATOM   2072 O  O   . THR A  1 258 ? 17.73514 23.89340  -27.92895 1.000 15.97768 ? 258 THR A O   1 
ATOM   2073 C  CB  . THR A  1 258 ? 15.03299 23.85826  -26.09156 1.000 15.61310 ? 258 THR A CB  1 
ATOM   2074 O  OG1 . THR A  1 258 ? 14.49768 23.25480  -24.90668 1.000 26.55755 ? 258 THR A OG1 1 
ATOM   2075 C  CG2 . THR A  1 258 ? 14.83945 22.91983  -27.27671 1.000 24.08148 ? 258 THR A CG2 1 
ATOM   2076 N  N   . ARG A  1 259 ? 16.95163 25.95849  -27.48546 1.000 18.57751 ? 259 ARG A N   1 
ATOM   2077 C  CA  . ARG A  1 259 ? 17.19615 26.47949  -28.82425 1.000 13.60719 ? 259 ARG A CA  1 
ATOM   2078 C  C   . ARG A  1 259 ? 18.66565 26.36231  -29.22025 1.000 14.70938 ? 259 ARG A C   1 
ATOM   2079 O  O   . ARG A  1 259 ? 19.56028 26.77090  -28.47401 1.000 14.32044 ? 259 ARG A O   1 
ATOM   2080 C  CB  . ARG A  1 259 ? 16.74209 27.93593  -28.89614 1.000 14.82179 ? 259 ARG A CB  1 
ATOM   2081 C  CG  . ARG A  1 259 ? 17.00995 28.61124  -30.22285 1.000 18.70806 ? 259 ARG A CG  1 
ATOM   2082 C  CD  . ARG A  1 259 ? 16.59897 30.07445  -30.18079 1.000 18.07612 ? 259 ARG A CD  1 
ATOM   2083 N  NE  . ARG A  1 259 ? 15.15222 30.25215  -30.17389 1.000 17.57310 ? 259 ARG A NE  1 
ATOM   2084 C  CZ  . ARG A  1 259 ? 14.42613 30.50651  -31.25375 1.000 17.78346 ? 259 ARG A CZ  1 
ATOM   2085 N  NH1 . ARG A  1 259 ? 14.98188 30.62039  -32.44891 1.000 15.05972 ? 259 ARG A NH1 1 
ATOM   2086 N  NH2 . ARG A  1 259 ? 13.11074 30.65945  -31.13011 1.000 20.75451 ? 259 ARG A NH2 1 
ATOM   2087 N  N   . ILE A  1 260 ? 18.90846 25.79979  -30.40285 1.000 12.84347 ? 260 ILE A N   1 
ATOM   2088 C  CA  . ILE A  1 260 ? 20.23115 25.76663  -31.01651 1.000 10.92776 ? 260 ILE A CA  1 
ATOM   2089 C  C   . ILE A  1 260 ? 20.32444 26.92739  -31.99602 1.000 14.19317 ? 260 ILE A C   1 
ATOM   2090 O  O   . ILE A  1 260 ? 19.40138 27.15654  -32.78754 1.000 17.41373 ? 260 ILE A O   1 
ATOM   2091 C  CB  . ILE A  1 260 ? 20.48757 24.42639  -31.72810 1.000 14.23584 ? 260 ILE A CB  1 
ATOM   2092 C  CG1 . ILE A  1 260 ? 20.39199 23.26225  -30.74087 1.000 15.90052 ? 260 ILE A CG1 1 
ATOM   2093 C  CG2 . ILE A  1 260 ? 21.84616 24.43298  -32.41733 1.000 7.82345  ? 260 ILE A CG2 1 
ATOM   2094 C  CD1 . ILE A  1 260 ? 20.55780 21.90433  -31.38794 1.000 10.35820 ? 260 ILE A CD1 1 
ATOM   2095 N  N   . PHE A  1 261 ? 21.42988 27.66165  -31.94417 1.000 12.96470 ? 261 PHE A N   1 
ATOM   2096 C  CA  . PHE A  1 261 ? 21.63649 28.81655  -32.80272 1.000 13.01141 ? 261 PHE A CA  1 
ATOM   2097 C  C   . PHE A  1 261 ? 22.56895 28.47321  -33.95669 1.000 15.12025 ? 261 PHE A C   1 
ATOM   2098 O  O   . PHE A  1 261 ? 23.40645 27.57248  -33.86057 1.000 13.92153 ? 261 PHE A O   1 
ATOM   2099 C  CB  . PHE A  1 261 ? 22.22231 29.99038  -32.01498 1.000 15.58970 ? 261 PHE A CB  1 
ATOM   2100 C  CG  . PHE A  1 261 ? 21.27874 30.58464  -31.01397 1.000 12.37349 ? 261 PHE A CG  1 
ATOM   2101 C  CD1 . PHE A  1 261 ? 20.26955 31.44018  -31.41997 1.000 15.64633 ? 261 PHE A CD1 1 
ATOM   2102 C  CD2 . PHE A  1 261 ? 21.40991 30.30105  -29.66493 1.000 11.81420 ? 261 PHE A CD2 1 
ATOM   2103 C  CE1 . PHE A  1 261 ? 19.40313 31.99641  -30.50146 1.000 13.86783 ? 261 PHE A CE1 1 
ATOM   2104 C  CE2 . PHE A  1 261 ? 20.54569 30.85257  -28.74073 1.000 13.93293 ? 261 PHE A CE2 1 
ATOM   2105 C  CZ  . PHE A  1 261 ? 19.54016 31.70130  -29.15983 1.000 19.90954 ? 261 PHE A CZ  1 
ATOM   2106 N  N   . GLU A  1 262 ? 22.41257 29.20982  -35.05555 1.000 13.15287 ? 262 GLU A N   1 
ATOM   2107 C  CA  . GLU A  1 262 ? 23.34998 29.18733  -36.17749 1.000 13.06547 ? 262 GLU A CA  1 
ATOM   2108 C  C   . GLU A  1 262 ? 23.66052 30.64816  -36.48653 1.000 11.27142 ? 262 GLU A C   1 
ATOM   2109 O  O   . GLU A  1 262 ? 23.01101 31.26761  -37.33286 1.000 11.32329 ? 262 GLU A O   1 
ATOM   2110 C  CB  . GLU A  1 262 ? 22.78196 28.44936  -37.38250 1.000 14.56484 ? 262 GLU A CB  1 
ATOM   2111 C  CG  . GLU A  1 262 ? 23.79273 28.25998  -38.50403 1.000 20.48735 ? 262 GLU A CG  1 
ATOM   2112 C  CD  . GLU A  1 262 ? 23.27445 27.37530  -39.61734 1.000 21.07623 ? 262 GLU A CD  1 
ATOM   2113 O  OE1 . GLU A  1 262 ? 22.18116 26.79703  -39.46148 1.000 25.91658 ? 262 GLU A OE1 1 
ATOM   2114 O  OE2 . GLU A  1 262 ? 23.96148 27.25727  -40.64999 1.000 21.97558 ? 262 GLU A OE2 1 
ATOM   2115 N  N   . LEU A  1 263 ? 24.65144 31.19429  -35.78763 1.000 11.84635 ? 263 LEU A N   1 
ATOM   2116 C  CA  . LEU A  1 263 ? 24.94332 32.61849  -35.85732 1.000 16.36121 ? 263 LEU A CA  1 
ATOM   2117 C  C   . LEU A  1 263 ? 25.74548 32.95726  -37.10691 1.000 17.75484 ? 263 LEU A C   1 
ATOM   2118 O  O   . LEU A  1 263 ? 26.59602 32.18020  -37.54880 1.000 19.01205 ? 263 LEU A O   1 
ATOM   2119 C  CB  . LEU A  1 263 ? 25.71457 33.06079  -34.61399 1.000 14.86463 ? 263 LEU A CB  1 
ATOM   2120 C  CG  . LEU A  1 263 ? 25.12427 32.64441  -33.26706 1.000 12.78639 ? 263 LEU A CG  1 
ATOM   2121 C  CD1 . LEU A  1 263 ? 25.97520 33.17366  -32.12343 1.000 8.40081  ? 263 LEU A CD1 1 
ATOM   2122 C  CD2 . LEU A  1 263 ? 23.68884 33.12306  -33.14214 1.000 13.86905 ? 263 LEU A CD2 1 
ATOM   2123 N  N   . TYR A  1 264 ? 25.47305 34.13153  -37.67045 1.000 17.54032 ? 264 TYR A N   1 
ATOM   2124 C  CA  . TYR A  1 264 ? 26.23753 34.63164  -38.80391 1.000 24.45053 ? 264 TYR A CA  1 
ATOM   2125 C  C   . TYR A  1 264 ? 26.04708 36.13807  -38.89421 1.000 19.38594 ? 264 TYR A C   1 
ATOM   2126 O  O   . TYR A  1 264 ? 25.04259 36.67886  -38.42479 1.000 17.87746 ? 264 TYR A O   1 
ATOM   2127 C  CB  . TYR A  1 264 ? 25.82128 33.95564  -40.11821 1.000 19.18646 ? 264 TYR A CB  1 
ATOM   2128 C  CG  . TYR A  1 264 ? 24.44943 34.34656  -40.62545 1.000 21.78102 ? 264 TYR A CG  1 
ATOM   2129 C  CD1 . TYR A  1 264 ? 23.30957 33.67996  -40.19341 1.000 21.18631 ? 264 TYR A CD1 1 
ATOM   2130 C  CD2 . TYR A  1 264 ? 24.29601 35.37445  -41.54876 1.000 25.43226 ? 264 TYR A CD2 1 
ATOM   2131 C  CE1 . TYR A  1 264 ? 22.05445 34.03264  -40.66005 1.000 19.39244 ? 264 TYR A CE1 1 
ATOM   2132 C  CE2 . TYR A  1 264 ? 23.04727 35.73429  -42.01915 1.000 24.79384 ? 264 TYR A CE2 1 
ATOM   2133 C  CZ  . TYR A  1 264 ? 21.93077 35.06020  -41.57390 1.000 24.14465 ? 264 TYR A CZ  1 
ATOM   2134 O  OH  . TYR A  1 264 ? 20.68778 35.41987  -42.04301 1.000 22.60435 ? 264 TYR A OH  1 
ATOM   2135 N  N   . PHE A  1 265 ? 27.02550 36.80617  -39.49730 1.000 17.98666 ? 265 PHE A N   1 
ATOM   2136 C  CA  . PHE A  1 265 ? 26.95045 38.24032  -39.73281 1.000 20.67917 ? 265 PHE A CA  1 
ATOM   2137 C  C   . PHE A  1 265 ? 26.29596 38.51522  -41.08000 1.000 23.00344 ? 265 PHE A C   1 
ATOM   2138 O  O   . PHE A  1 265 ? 26.51494 37.78535  -42.05077 1.000 22.99712 ? 265 PHE A O   1 
ATOM   2139 C  CB  . PHE A  1 265 ? 28.34418 38.86923  -39.68815 1.000 21.62977 ? 265 PHE A CB  1 
ATOM   2140 C  CG  . PHE A  1 265 ? 28.84661 39.13439  -38.29800 1.000 18.33520 ? 265 PHE A CG  1 
ATOM   2141 C  CD1 . PHE A  1 265 ? 28.00499 39.66100  -37.33235 1.000 17.86867 ? 265 PHE A CD1 1 
ATOM   2142 C  CD2 . PHE A  1 265 ? 30.15812 38.85312  -37.95517 1.000 17.91215 ? 265 PHE A CD2 1 
ATOM   2143 C  CE1 . PHE A  1 265 ? 28.46289 39.90840  -36.05263 1.000 16.87458 ? 265 PHE A CE1 1 
ATOM   2144 C  CE2 . PHE A  1 265 ? 30.62137 39.09574  -36.67523 1.000 24.15004 ? 265 PHE A CE2 1 
ATOM   2145 C  CZ  . PHE A  1 265 ? 29.77200 39.62400  -35.72290 1.000 21.04974 ? 265 PHE A CZ  1 
ATOM   2146 N  N   . ASP A  1 266 ? 25.48484 39.57329  -41.13219 1.000 27.07574 ? 266 ASP A N   1 
ATOM   2147 C  CA  . ASP A  1 266 ? 24.82298 39.95265  -42.37440 1.000 29.76563 ? 266 ASP A CA  1 
ATOM   2148 C  C   . ASP A  1 266 ? 25.75985 40.64631  -43.35432 1.000 27.02336 ? 266 ASP A C   1 
ATOM   2149 O  O   . ASP A  1 266 ? 25.35186 40.91840  -44.48817 1.000 34.69504 ? 266 ASP A O   1 
ATOM   2150 C  CB  . ASP A  1 266 ? 23.61635 40.85145  -42.08387 1.000 22.44757 ? 266 ASP A CB  1 
ATOM   2151 C  CG  . ASP A  1 266 ? 24.01208 42.20212  -41.52028 1.000 28.43682 ? 266 ASP A CG  1 
ATOM   2152 O  OD1 . ASP A  1 266 ? 25.10792 42.31166  -40.92981 1.000 29.19510 ? 266 ASP A OD1 1 
ATOM   2153 O  OD2 . ASP A  1 266 ? 23.21907 43.15635  -41.66361 1.000 27.07612 ? 266 ASP A OD2 1 
ATOM   2154 N  N   . HIS A  1 267 ? 26.98829 40.94364  -42.94670 1.000 19.94412 ? 267 HIS A N   1 
ATOM   2155 C  CA  . HIS A  1 267 ? 28.03222 41.42346  -43.83793 1.000 28.37436 ? 267 HIS A CA  1 
ATOM   2156 C  C   . HIS A  1 267 ? 29.07950 40.33316  -44.02179 1.000 31.41670 ? 267 HIS A C   1 
ATOM   2157 O  O   . HIS A  1 267 ? 29.11829 39.34439  -43.28485 1.000 34.36140 ? 267 HIS A O   1 
ATOM   2158 C  CB  . HIS A  1 267 ? 28.67705 42.70387  -43.29235 1.000 27.81736 ? 267 HIS A CB  1 
ATOM   2159 C  CG  . HIS A  1 267 ? 27.78623 43.90560  -43.35700 1.000 23.46566 ? 267 HIS A CG  1 
ATOM   2160 N  ND1 . HIS A  1 267 ? 26.63801 44.02347  -42.60377 1.000 27.94489 ? 267 HIS A ND1 1 
ATOM   2161 C  CD2 . HIS A  1 267 ? 27.87493 45.04247  -44.08738 1.000 24.89688 ? 267 HIS A CD2 1 
ATOM   2162 C  CE1 . HIS A  1 267 ? 26.05826 45.18106  -42.86680 1.000 26.47566 ? 267 HIS A CE1 1 
ATOM   2163 N  NE2 . HIS A  1 267 ? 26.78872 45.81866  -43.76373 1.000 23.74437 ? 267 HIS A NE2 1 
ATOM   2164 N  N   . ASP A  1 268 ? 29.94123 40.52265  -45.02022 1.000 30.52691 ? 268 ASP A N   1 
ATOM   2165 C  CA  . ASP A  1 268 ? 30.99900 39.55533  -45.28924 1.000 27.62912 ? 268 ASP A CA  1 
ATOM   2166 C  C   . ASP A  1 268 ? 32.08372 39.64277  -44.22169 1.000 29.56400 ? 268 ASP A C   1 
ATOM   2167 O  O   . ASP A  1 268 ? 33.24696 39.92694  -44.52641 1.000 26.78814 ? 268 ASP A O   1 
ATOM   2168 C  CB  . ASP A  1 268 ? 31.59362 39.77981  -46.68159 1.000 33.92030 ? 268 ASP A CB  1 
ATOM   2169 C  CG  . ASP A  1 268 ? 32.48426 38.63555  -47.12776 1.000 39.60815 ? 268 ASP A CG  1 
ATOM   2170 O  OD1 . ASP A  1 268 ? 32.51057 37.59495  -46.43641 1.000 32.73496 ? 268 ASP A OD1 1 
ATOM   2171 O  OD2 . ASP A  1 268 ? 33.16115 38.77908  -48.16812 1.000 44.44659 ? 268 ASP A OD2 1 
ATOM   2172 N  N   . ILE A  1 269 ? 31.70789 39.40450  -42.96762 1.000 31.32003 ? 269 ILE A N   1 
ATOM   2173 C  CA  . ILE A  1 269 ? 32.62237 39.44842  -41.83508 1.000 29.40911 ? 269 ILE A CA  1 
ATOM   2174 C  C   . ILE A  1 269 ? 32.69491 38.05455  -41.23136 1.000 28.88538 ? 269 ILE A C   1 
ATOM   2175 O  O   . ILE A  1 269 ? 31.66704 37.39398  -41.04509 1.000 24.81606 ? 269 ILE A O   1 
ATOM   2176 C  CB  . ILE A  1 269 ? 32.17904 40.48726  -40.78443 1.000 26.98577 ? 269 ILE A CB  1 
ATOM   2177 C  CG1 . ILE A  1 269 ? 32.11241 41.87991  -41.41482 1.000 23.63939 ? 269 ILE A CG1 1 
ATOM   2178 C  CG2 . ILE A  1 269 ? 33.12657 40.48704  -39.59785 1.000 23.31128 ? 269 ILE A CG2 1 
ATOM   2179 C  CD1 . ILE A  1 269 ? 31.76814 42.97981  -40.43747 1.000 16.14590 ? 269 ILE A CD1 1 
ATOM   2180 N  N   . THR A  1 270 ? 33.90997 37.61008  -40.92864 1.000 27.45105 ? 270 THR A N   1 
ATOM   2181 C  CA  . THR A  1 270 ? 34.16996 36.23147  -40.54585 1.000 27.63021 ? 270 THR A CA  1 
ATOM   2182 C  C   . THR A  1 270 ? 34.47242 36.13063  -39.05718 1.000 29.04722 ? 270 THR A C   1 
ATOM   2183 O  O   . THR A  1 270 ? 35.13425 37.00301  -38.48601 1.000 31.48191 ? 270 THR A O   1 
ATOM   2184 C  CB  . THR A  1 270 ? 35.34430 35.66059  -41.34547 1.000 33.39510 ? 270 THR A CB  1 
ATOM   2185 O  OG1 . THR A  1 270 ? 35.18725 35.98920  -42.73155 1.000 40.85444 ? 270 THR A OG1 1 
ATOM   2186 C  CG2 . THR A  1 270 ? 35.39306 34.15671  -41.20293 1.000 38.06051 ? 270 THR A CG2 1 
ATOM   2187 N  N   . PHE A  1 271 ? 33.97833 35.06343  -38.43358 1.000 30.04894 ? 271 PHE A N   1 
ATOM   2188 C  CA  . PHE A  1 271 ? 34.39604 34.71337  -37.08489 1.000 18.65694 ? 271 PHE A CA  1 
ATOM   2189 C  C   . PHE A  1 271 ? 35.74913 34.01561  -37.14475 1.000 22.61002 ? 271 PHE A C   1 
ATOM   2190 O  O   . PHE A  1 271 ? 35.96649 33.13665  -37.98503 1.000 25.74542 ? 271 PHE A O   1 
ATOM   2191 C  CB  . PHE A  1 271 ? 33.37324 33.79556  -36.41283 1.000 19.98755 ? 271 PHE A CB  1 
ATOM   2192 C  CG  . PHE A  1 271 ? 31.94917 34.26212  -36.53321 1.000 27.41602 ? 271 PHE A CG  1 
ATOM   2193 C  CD1 . PHE A  1 271 ? 31.49786 35.35636  -35.81412 1.000 26.33590 ? 271 PHE A CD1 1 
ATOM   2194 C  CD2 . PHE A  1 271 ? 31.05321 33.58550  -37.34518 1.000 21.21078 ? 271 PHE A CD2 1 
ATOM   2195 C  CE1 . PHE A  1 271 ? 30.18490 35.77805  -35.91404 1.000 24.40259 ? 271 PHE A CE1 1 
ATOM   2196 C  CE2 . PHE A  1 271 ? 29.73900 34.00209  -37.44997 1.000 23.90689 ? 271 PHE A CE2 1 
ATOM   2197 C  CZ  . PHE A  1 271 ? 29.30432 35.10034  -36.73384 1.000 23.78557 ? 271 PHE A CZ  1 
ATOM   2198 N  N   . HIS A  1 272 ? 36.65851 34.40949  -36.26219 1.000 18.84957 ? 272 HIS A N   1 
ATOM   2199 C  CA  . HIS A  1 272 ? 37.93495 33.72258  -36.08265 1.000 17.43959 ? 272 HIS A CA  1 
ATOM   2200 C  C   . HIS A  1 272 ? 37.89558 33.07463  -34.70311 1.000 19.29757 ? 272 HIS A C   1 
ATOM   2201 O  O   . HIS A  1 272 ? 38.16220 33.72987  -33.69130 1.000 21.89676 ? 272 HIS A O   1 
ATOM   2202 C  CB  . HIS A  1 272 ? 39.11239 34.68367  -36.22220 1.000 23.23986 ? 272 HIS A CB  1 
ATOM   2203 C  CG  . HIS A  1 272 ? 39.22962 35.30645  -37.57846 1.000 25.23090 ? 272 HIS A CG  1 
ATOM   2204 N  ND1 . HIS A  1 272 ? 38.62021 36.49888  -37.90558 1.000 25.41745 ? 272 HIS A ND1 1 
ATOM   2205 C  CD2 . HIS A  1 272 ? 39.88709 34.90247  -38.69124 1.000 25.65855 ? 272 HIS A CD2 1 
ATOM   2206 C  CE1 . HIS A  1 272 ? 38.89640 36.80230  -39.16135 1.000 24.80281 ? 272 HIS A CE1 1 
ATOM   2207 N  NE2 . HIS A  1 272 ? 39.66315 35.84964  -39.66088 1.000 29.14253 ? 272 HIS A NE2 1 
ATOM   2208 N  N   . GLN A  1 273 ? 37.55340 31.79001  -34.66365 1.000 16.98501 ? 273 GLN A N   1 
ATOM   2209 C  CA  . GLN A  1 273 ? 37.37945 31.09606  -33.39525 1.000 18.06134 ? 273 GLN A CA  1 
ATOM   2210 C  C   . GLN A  1 273 ? 38.72760 30.66026  -32.83723 1.000 14.24079 ? 273 GLN A C   1 
ATOM   2211 O  O   . GLN A  1 273 ? 39.51388 30.00029  -33.52414 1.000 14.73175 ? 273 GLN A O   1 
ATOM   2212 C  CB  . GLN A  1 273 ? 36.45824 29.88889  -33.56500 1.000 18.23903 ? 273 GLN A CB  1 
ATOM   2213 C  CG  . GLN A  1 273 ? 36.23413 29.11167  -32.28122 1.000 12.98796 ? 273 GLN A CG  1 
ATOM   2214 C  CD  . GLN A  1 273 ? 34.91392 28.37485  -32.26893 1.000 12.74352 ? 273 GLN A CD  1 
ATOM   2215 O  OE1 . GLN A  1 273 ? 34.19796 28.34428  -33.26934 1.000 12.78820 ? 273 GLN A OE1 1 
ATOM   2216 N  NE2 . GLN A  1 273 ? 34.57764 27.78316  -31.12799 1.000 12.32883 ? 273 GLN A NE2 1 
ATOM   2217 N  N   . ILE A  1 274 ? 38.98689 31.02737  -31.58405 1.000 15.01468 ? 274 ILE A N   1 
ATOM   2218 C  CA  . ILE A  1 274 ? 40.25370 30.72174  -30.92816 1.000 13.77702 ? 274 ILE A CA  1 
ATOM   2219 C  C   . ILE A  1 274 ? 40.10058 29.75892  -29.76296 1.000 13.40729 ? 274 ILE A C   1 
ATOM   2220 O  O   . ILE A  1 274 ? 41.12145 29.29451  -29.22919 1.000 14.74717 ? 274 ILE A O   1 
ATOM   2221 C  CB  . ILE A  1 274 ? 40.96306 32.00573  -30.44974 1.000 13.77802 ? 274 ILE A CB  1 
ATOM   2222 C  CG1 . ILE A  1 274 ? 40.07654 32.75706  -29.45351 1.000 13.52056 ? 274 ILE A CG1 1 
ATOM   2223 C  CG2 . ILE A  1 274 ? 41.32247 32.89005  -31.63447 1.000 9.47226  ? 274 ILE A CG2 1 
ATOM   2224 C  CD1 . ILE A  1 274 ? 40.75624 33.93601  -28.79384 1.000 14.06965 ? 274 ILE A CD1 1 
ATOM   2225 N  N   . GLY A  1 275 ? 38.87821 29.44507  -29.34509 1.000 14.15595 ? 275 GLY A N   1 
ATOM   2226 C  CA  . GLY A  1 275 ? 38.69377 28.58035  -28.19648 1.000 13.82924 ? 275 GLY A CA  1 
ATOM   2227 C  C   . GLY A  1 275 ? 37.31772 27.96049  -28.16979 1.000 13.18870 ? 275 GLY A C   1 
ATOM   2228 O  O   . GLY A  1 275 ? 36.37888 28.44516  -28.80993 1.000 12.01904 ? 275 GLY A O   1 
ATOM   2229 N  N   . THR A  1 276 ? 37.21001 26.86887  -27.41216 1.000 14.45549 ? 276 THR A N   1 
ATOM   2230 C  CA  . THR A  1 276 ? 35.94417 26.16569  -27.24628 1.000 14.69257 ? 276 THR A CA  1 
ATOM   2231 C  C   . THR A  1 276 ? 35.57083 26.08122  -25.77167 1.000 14.62506 ? 276 THR A C   1 
ATOM   2232 O  O   . THR A  1 276 ? 36.01556 26.90661  -24.96742 1.000 18.36984 ? 276 THR A O   1 
ATOM   2233 C  CB  . THR A  1 276 ? 36.02000 24.76522  -27.85788 1.000 14.39507 ? 276 THR A CB  1 
ATOM   2234 O  OG1 . THR A  1 276 ? 37.14538 24.06501  -27.31353 1.000 12.11978 ? 276 THR A OG1 1 
ATOM   2235 C  CG2 . THR A  1 276 ? 36.16402 24.85126  -29.37067 1.000 15.76552 ? 276 THR A CG2 1 
ATOM   2236 N  N   . ASP A  1 277 ? 34.75883 25.08399  -25.40908 1.000 13.90865 ? 277 ASP A N   1 
ATOM   2237 C  CA  . ASP A  1 277 ? 34.31504 24.95330  -24.02428 1.000 12.37625 ? 277 ASP A CA  1 
ATOM   2238 C  C   . ASP A  1 277 ? 35.49480 24.78031  -23.07563 1.000 15.09195 ? 277 ASP A C   1 
ATOM   2239 O  O   . ASP A  1 277 ? 35.53471 25.39483  -22.00330 1.000 14.39068 ? 277 ASP A O   1 
ATOM   2240 C  CB  . ASP A  1 277 ? 33.35411 23.77129  -23.88666 1.000 14.47756 ? 277 ASP A CB  1 
ATOM   2241 C  CG  . ASP A  1 277 ? 32.22773 23.80841  -24.90019 1.000 13.64180 ? 277 ASP A CG  1 
ATOM   2242 O  OD1 . ASP A  1 277 ? 31.94371 24.89695  -25.44375 1.000 15.65002 ? 277 ASP A OD1 1 
ATOM   2243 O  OD2 . ASP A  1 277 ? 31.62327 22.74403  -25.14866 1.000 11.29806 ? 277 ASP A OD2 1 
ATOM   2244 N  N   . GLY A  1 278 ? 36.46799 23.95693  -23.45723 1.000 16.34356 ? 278 GLY A N   1 
ATOM   2245 C  CA  . GLY A  1 278 ? 37.55731 23.60022  -22.57051 1.000 14.01119 ? 278 GLY A CA  1 
ATOM   2246 C  C   . GLY A  1 278 ? 38.72057 24.57081  -22.53524 1.000 13.27749 ? 278 GLY A C   1 
ATOM   2247 O  O   . GLY A  1 278 ? 39.50042 24.56593  -21.57872 1.000 19.26002 ? 278 GLY A O   1 
ATOM   2248 N  N   . GLY A  1 279 ? 38.85822 25.39284  -23.56532 1.000 15.50679 ? 279 GLY A N   1 
ATOM   2249 C  CA  . GLY A  1 279 ? 39.90555 26.39337  -23.59926 1.000 18.08446 ? 279 GLY A CA  1 
ATOM   2250 C  C   . GLY A  1 279 ? 40.31476 26.71251  -25.02621 1.000 16.01604 ? 279 GLY A C   1 
ATOM   2251 O  O   . GLY A  1 279 ? 39.54078 26.53745  -25.96023 1.000 19.84418 ? 279 GLY A O   1 
ATOM   2252 N  N   . LEU A  1 280 ? 41.55486 27.17275  -25.15608 1.000 15.61596 ? 280 LEU A N   1 
ATOM   2253 C  CA  . LEU A  1 280 ? 42.06582 27.64911  -26.43408 1.000 17.44612 ? 280 LEU A CA  1 
ATOM   2254 C  C   . LEU A  1 280 ? 42.25053 26.50348  -27.42176 1.000 17.96789 ? 280 LEU A C   1 
ATOM   2255 O  O   . LEU A  1 280 ? 42.60875 25.38146  -27.05288 1.000 23.52620 ? 280 LEU A O   1 
ATOM   2256 C  CB  . LEU A  1 280 ? 43.40008 28.37060  -26.23775 1.000 17.80379 ? 280 LEU A CB  1 
ATOM   2257 C  CG  . LEU A  1 280 ? 43.39133 29.62274  -25.36204 1.000 20.15286 ? 280 LEU A CG  1 
ATOM   2258 C  CD1 . LEU A  1 280 ? 44.81271 30.05165  -25.04422 1.000 19.75904 ? 280 LEU A CD1 1 
ATOM   2259 C  CD2 . LEU A  1 280 ? 42.63383 30.74506  -26.04883 1.000 13.72628 ? 280 LEU A CD2 1 
ATOM   2260 N  N   . LEU A  1 281 ? 41.99792 26.80146  -28.69237 1.000 15.82575 ? 281 LEU A N   1 
ATOM   2261 C  CA  . LEU A  1 281 ? 42.36134 25.90298  -29.77344 1.000 15.65509 ? 281 LEU A CA  1 
ATOM   2262 C  C   . LEU A  1 281 ? 43.86790 25.97935  -30.01035 1.000 18.38858 ? 281 LEU A C   1 
ATOM   2263 O  O   . LEU A  1 281 ? 44.58457 26.76136  -29.38034 1.000 22.58495 ? 281 LEU A O   1 
ATOM   2264 C  CB  . LEU A  1 281 ? 41.58215 26.25248  -31.03884 1.000 12.56640 ? 281 LEU A CB  1 
ATOM   2265 C  CG  . LEU A  1 281 ? 40.06426 26.08469  -30.97909 1.000 17.37225 ? 281 LEU A CG  1 
ATOM   2266 C  CD1 . LEU A  1 281 ? 39.41711 26.61261  -32.24765 1.000 17.10247 ? 281 LEU A CD1 1 
ATOM   2267 C  CD2 . LEU A  1 281 ? 39.70184 24.62754  -30.76301 1.000 14.95933 ? 281 LEU A CD2 1 
ATOM   2268 N  N   . GLN A  1 282 ? 44.36390 25.15458  -30.93094 1.000 22.54246 ? 282 GLN A N   1 
ATOM   2269 C  CA  . GLN A  1 282 ? 45.78104 25.21930  -31.26708 1.000 26.42996 ? 282 GLN A CA  1 
ATOM   2270 C  C   . GLN A  1 282 ? 46.06973 26.36243  -32.23257 1.000 26.21200 ? 282 GLN A C   1 
ATOM   2271 O  O   . GLN A  1 282 ? 47.08996 27.04797  -32.10027 1.000 25.78954 ? 282 GLN A O   1 
ATOM   2272 C  CB  . GLN A  1 282 ? 46.24580 23.88428  -31.84957 1.000 25.03982 ? 282 GLN A CB  1 
ATOM   2273 C  CG  . GLN A  1 282 ? 46.23318 22.74470  -30.84246 1.000 29.93471 ? 282 GLN A CG  1 
ATOM   2274 C  CD  . GLN A  1 282 ? 46.87505 21.48135  -31.37773 1.000 44.30020 ? 282 GLN A CD  1 
ATOM   2275 O  OE1 . GLN A  1 282 ? 46.97829 21.28749  -32.58947 1.000 52.42775 ? 282 GLN A OE1 1 
ATOM   2276 N  NE2 . GLN A  1 282 ? 47.31775 20.61499  -30.47327 1.000 47.10840 ? 282 GLN A NE2 1 
ATOM   2277 N  N   . HIS A  1 283 ? 45.18292 26.58529  -33.19688 1.000 21.44049 ? 283 HIS A N   1 
ATOM   2278 C  CA  . HIS A  1 283 ? 45.29726 27.66200  -34.16659 1.000 23.13810 ? 283 HIS A CA  1 
ATOM   2279 C  C   . HIS A  1 283 ? 43.91424 28.25376  -34.38801 1.000 20.40828 ? 283 HIS A C   1 
ATOM   2280 O  O   . HIS A  1 283 ? 42.90665 27.56446  -34.18846 1.000 18.93189 ? 283 HIS A O   1 
ATOM   2281 C  CB  . HIS A  1 283 ? 45.87028 27.16572  -35.50501 1.000 17.51726 ? 283 HIS A CB  1 
ATOM   2282 C  CG  . HIS A  1 283 ? 47.02539 26.22364  -35.35898 1.000 35.30245 ? 283 HIS A CG  1 
ATOM   2283 N  ND1 . HIS A  1 283 ? 48.33471 26.61295  -35.54556 1.000 41.96173 ? 283 HIS A ND1 1 
ATOM   2284 C  CD2 . HIS A  1 283 ? 47.06636 24.90644  -35.04657 1.000 43.30472 ? 283 HIS A CD2 1 
ATOM   2285 C  CE1 . HIS A  1 283 ? 49.13197 25.57688  -35.35329 1.000 34.33185 ? 283 HIS A CE1 1 
ATOM   2286 N  NE2 . HIS A  1 283 ? 48.38748 24.52939  -35.04792 1.000 39.43553 ? 283 HIS A NE2 1 
ATOM   2287 N  N   . PRO A  1 284 ? 43.83022 29.52537  -34.78138 1.000 16.41639 ? 284 PRO A N   1 
ATOM   2288 C  CA  . PRO A  1 284 ? 42.51837 30.11071  -35.07793 1.000 17.11618 ? 284 PRO A CA  1 
ATOM   2289 C  C   . PRO A  1 284 ? 41.84829 29.39468  -36.23945 1.000 17.57040 ? 284 PRO A C   1 
ATOM   2290 O  O   . PRO A  1 284 ? 42.50804 28.85987  -37.13270 1.000 20.23706 ? 284 PRO A O   1 
ATOM   2291 C  CB  . PRO A  1 284 ? 42.84728 31.56511  -35.43305 1.000 16.69235 ? 284 PRO A CB  1 
ATOM   2292 C  CG  . PRO A  1 284 ? 44.15759 31.82498  -34.78337 1.000 23.22437 ? 284 PRO A CG  1 
ATOM   2293 C  CD  . PRO A  1 284 ? 44.90608 30.52824  -34.84939 1.000 21.12082 ? 284 PRO A CD  1 
ATOM   2294 N  N   . VAL A  1 285 ? 40.51807 29.38496  -36.21525 1.000 15.82628 ? 285 VAL A N   1 
ATOM   2295 C  CA  . VAL A  1 285 ? 39.71172 28.73251  -37.24067 1.000 18.98691 ? 285 VAL A CA  1 
ATOM   2296 C  C   . VAL A  1 285 ? 38.80728 29.78234  -37.87232 1.000 21.23973 ? 285 VAL A C   1 
ATOM   2297 O  O   . VAL A  1 285 ? 38.00108 30.41586  -37.17937 1.000 22.34579 ? 285 VAL A O   1 
ATOM   2298 C  CB  . VAL A  1 285 ? 38.88869 27.56741  -36.66891 1.000 15.43153 ? 285 VAL A CB  1 
ATOM   2299 C  CG1 . VAL A  1 285 ? 38.16186 26.83779  -37.78344 1.000 14.05012 ? 285 VAL A CG1 1 
ATOM   2300 C  CG2 . VAL A  1 285 ? 39.78785 26.60912  -35.90614 1.000 18.59345 ? 285 VAL A CG2 1 
ATOM   2301 N  N   . LYS A  1 286 ? 38.94280 29.96215  -39.18377 1.000 21.02323 ? 286 LYS A N   1 
ATOM   2302 C  CA  . LYS A  1 286 ? 38.15050 30.92946  -39.93614 1.000 21.27267 ? 286 LYS A CA  1 
ATOM   2303 C  C   . LYS A  1 286 ? 36.79661 30.30459  -40.26026 1.000 27.63834 ? 286 LYS A C   1 
ATOM   2304 O  O   . LYS A  1 286 ? 36.70217 29.42601  -41.12345 1.000 29.26486 ? 286 LYS A O   1 
ATOM   2305 C  CB  . LYS A  1 286 ? 38.90316 31.33341  -41.20210 1.000 21.06103 ? 286 LYS A CB  1 
ATOM   2306 C  CG  . LYS A  1 286 ? 38.43607 32.61710  -41.86920 1.000 31.79964 ? 286 LYS A CG  1 
ATOM   2307 C  CD  . LYS A  1 286 ? 39.61661 33.55328  -42.11647 1.000 46.08699 ? 286 LYS A CD  1 
ATOM   2308 C  CE  . LYS A  1 286 ? 39.35890 34.52721  -43.26467 1.000 52.17718 ? 286 LYS A CE  1 
ATOM   2309 N  NZ  . LYS A  1 286 ? 38.49816 35.68450  -42.88552 1.000 47.16090 ? 286 LYS A NZ  1 
ATOM   2310 N  N   . VAL A  1 287 ? 35.74728 30.74171  -39.56295 1.000 23.15988 ? 287 VAL A N   1 
ATOM   2311 C  CA  . VAL A  1 287 ? 34.41174 30.17332  -39.71113 1.000 25.98588 ? 287 VAL A CA  1 
ATOM   2312 C  C   . VAL A  1 287 ? 33.42369 31.28752  -40.02594 1.000 25.55856 ? 287 VAL A C   1 
ATOM   2313 O  O   . VAL A  1 287 ? 33.48281 32.36980  -39.43228 1.000 25.46684 ? 287 VAL A O   1 
ATOM   2314 C  CB  . VAL A  1 287 ? 33.96249 29.41172  -38.44546 1.000 27.92933 ? 287 VAL A CB  1 
ATOM   2315 C  CG1 . VAL A  1 287 ? 32.87085 28.41324  -38.79243 1.000 27.89409 ? 287 VAL A CG1 1 
ATOM   2316 C  CG2 . VAL A  1 287 ? 35.13545 28.71741  -37.78475 1.000 33.41288 ? 287 VAL A CG2 1 
ATOM   2317 N  N   . ASN A  1 288 ? 32.49928 31.01144  -40.94715 1.000 24.84315 ? 288 ASN A N   1 
ATOM   2318 C  CA  . ASN A  1 288 ? 31.46637 31.97151  -41.31400 1.000 27.33509 ? 288 ASN A CA  1 
ATOM   2319 C  C   . ASN A  1 288 ? 30.19382 31.83332  -40.49072 1.000 22.00589 ? 288 ASN A C   1 
ATOM   2320 O  O   . ASN A  1 288 ? 29.43084 32.80076  -40.39209 1.000 22.18036 ? 288 ASN A O   1 
ATOM   2321 C  CB  . ASN A  1 288 ? 31.11697 31.83432  -42.79928 1.000 22.90326 ? 288 ASN A CB  1 
ATOM   2322 C  CG  . ASN A  1 288 ? 32.04444 32.63217  -43.68997 1.000 33.09998 ? 288 ASN A CG  1 
ATOM   2323 O  OD1 . ASN A  1 288 ? 32.38977 33.77236  -43.37991 1.000 43.18870 ? 288 ASN A OD1 1 
ATOM   2324 N  ND2 . ASN A  1 288 ? 32.45699 32.03614  -44.80238 1.000 32.88831 ? 288 ASN A ND2 1 
ATOM   2325 N  N   . GLU A  1 289 ? 29.94053 30.66457  -39.90666 1.000 22.72402 ? 289 GLU A N   1 
ATOM   2326 C  CA  . GLU A  1 289 ? 28.73355 30.43998  -39.12545 1.000 19.96535 ? 289 GLU A CA  1 
ATOM   2327 C  C   . GLU A  1 289 ? 29.05584 29.58781  -37.90900 1.000 19.39762 ? 289 GLU A C   1 
ATOM   2328 O  O   . GLU A  1 289 ? 29.83426 28.63475  -37.99624 1.000 23.91859 ? 289 GLU A O   1 
ATOM   2329 C  CB  . GLU A  1 289 ? 27.64088 29.76290  -39.95972 1.000 15.26038 ? 289 GLU A CB  1 
ATOM   2330 C  CG  . GLU A  1 289 ? 27.00349 30.67067  -40.99200 1.000 26.00187 ? 289 GLU A CG  1 
ATOM   2331 C  CD  . GLU A  1 289 ? 25.90605 29.98133  -41.76810 1.000 25.68899 ? 289 GLU A CD  1 
ATOM   2332 O  OE1 . GLU A  1 289 ? 25.93919 28.73721  -41.85561 1.000 26.95362 ? 289 GLU A OE1 1 
ATOM   2333 O  OE2 . GLU A  1 289 ? 25.01066 30.68152  -42.28594 1.000 27.84937 ? 289 GLU A OE2 1 
ATOM   2334 N  N   . LEU A  1 290 ? 28.44754 29.93508  -36.77902 1.000 15.50607 ? 290 LEU A N   1 
ATOM   2335 C  CA  . LEU A  1 290 ? 28.63061 29.21894  -35.52373 1.000 17.18895 ? 290 LEU A CA  1 
ATOM   2336 C  C   . LEU A  1 290 ? 27.34411 28.48523  -35.17626 1.000 12.26040 ? 290 LEU A C   1 
ATOM   2337 O  O   . LEU A  1 290 ? 26.31178 29.11925  -34.93492 1.000 14.16350 ? 290 LEU A O   1 
ATOM   2338 C  CB  . LEU A  1 290 ? 29.01003 30.17658  -34.39455 1.000 18.98115 ? 290 LEU A CB  1 
ATOM   2339 C  CG  . LEU A  1 290 ? 30.38698 30.83241  -34.44336 1.000 15.99788 ? 290 LEU A CG  1 
ATOM   2340 C  CD1 . LEU A  1 290 ? 30.51536 31.84392  -33.31663 1.000 19.76708 ? 290 LEU A CD1 1 
ATOM   2341 C  CD2 . LEU A  1 290 ? 31.47646 29.78006  -34.35015 1.000 14.62606 ? 290 LEU A CD2 1 
ATOM   2342 N  N   . VAL A  1 291 ? 27.40619 27.15858  -35.14957 1.000 12.29622 ? 291 VAL A N   1 
ATOM   2343 C  CA  . VAL A  1 291 ? 26.30894 26.34358  -34.64246 1.000 12.85123 ? 291 VAL A CA  1 
ATOM   2344 C  C   . VAL A  1 291 ? 26.59162 26.08753  -33.16736 1.000 12.80748 ? 291 VAL A C   1 
ATOM   2345 O  O   . VAL A  1 291 ? 27.51877 25.35094  -32.82214 1.000 12.93633 ? 291 VAL A O   1 
ATOM   2346 C  CB  . VAL A  1 291 ? 26.16051 25.03325  -35.42362 1.000 12.35804 ? 291 VAL A CB  1 
ATOM   2347 C  CG1 . VAL A  1 291 ? 24.98610 24.22810  -34.88321 1.000 9.10681  ? 291 VAL A CG1 1 
ATOM   2348 C  CG2 . VAL A  1 291 ? 25.97807 25.31858  -36.90658 1.000 8.43533  ? 291 VAL A CG2 1 
ATOM   2349 N  N   . ILE A  1 292 ? 25.79991 26.70643  -32.29629 1.000 11.94295 ? 292 ILE A N   1 
ATOM   2350 C  CA  . ILE A  1 292 ? 26.03139 26.68662  -30.85673 1.000 12.14242 ? 292 ILE A CA  1 
ATOM   2351 C  C   . ILE A  1 292 ? 24.78353 26.12684  -30.18787 1.000 11.63079 ? 292 ILE A C   1 
ATOM   2352 O  O   . ILE A  1 292 ? 23.73010 26.77700  -30.17680 1.000 12.93529 ? 292 ILE A O   1 
ATOM   2353 C  CB  . ILE A  1 292 ? 26.36830 28.08181  -30.31375 1.000 13.54649 ? 292 ILE A CB  1 
ATOM   2354 C  CG1 . ILE A  1 292 ? 27.45931 28.73348  -31.16617 1.000 13.32039 ? 292 ILE A CG1 1 
ATOM   2355 C  CG2 . ILE A  1 292 ? 26.80987 27.99883  -28.86119 1.000 11.30192 ? 292 ILE A CG2 1 
ATOM   2356 C  CD1 . ILE A  1 292 ? 27.80233 30.13975  -30.74260 1.000 17.18707 ? 292 ILE A CD1 1 
ATOM   2357 N  N   . ALA A  1 293 ? 24.89966 24.92802  -29.63083 1.000 11.44768 ? 293 ALA A N   1 
ATOM   2358 C  CA  . ALA A  1 293 ? 23.81816 24.30975  -28.88052 1.000 10.13380 ? 293 ALA A CA  1 
ATOM   2359 C  C   . ALA A  1 293 ? 23.80235 24.85560  -27.45817 1.000 13.99238 ? 293 ALA A C   1 
ATOM   2360 O  O   . ALA A  1 293 ? 24.72816 25.55653  -27.04204 1.000 14.85829 ? 293 ALA A O   1 
ATOM   2361 C  CB  . ALA A  1 293 ? 23.98992 22.79291  -28.89248 1.000 12.27843 ? 293 ALA A CB  1 
ATOM   2362 N  N   . PRO A  1 294 ? 22.74524 24.57964  -26.69230 1.000 11.85329 ? 294 PRO A N   1 
ATOM   2363 C  CA  . PRO A  1 294 ? 22.73659 24.98474  -25.28153 1.000 11.90252 ? 294 PRO A CA  1 
ATOM   2364 C  C   . PRO A  1 294 ? 23.97675 24.50289  -24.54245 1.000 13.54337 ? 294 PRO A C   1 
ATOM   2365 O  O   . PRO A  1 294 ? 24.40515 23.35543  -24.69229 1.000 15.89686 ? 294 PRO A O   1 
ATOM   2366 C  CB  . PRO A  1 294 ? 21.46402 24.32771  -24.74072 1.000 9.13062  ? 294 PRO A CB  1 
ATOM   2367 C  CG  . PRO A  1 294 ? 20.55134 24.30973  -25.90836 1.000 8.90642  ? 294 PRO A CG  1 
ATOM   2368 C  CD  . PRO A  1 294 ? 21.42069 24.08965  -27.12167 1.000 10.47962 ? 294 PRO A CD  1 
ATOM   2369 N  N   . ALA A  1 295 ? 24.56218 25.40712  -23.75517 1.000 11.62479 ? 295 ALA A N   1 
ATOM   2370 C  CA  . ALA A  1 295 ? 25.72366 25.24456  -22.88715 1.000 11.61278 ? 295 ALA A CA  1 
ATOM   2371 C  C   . ALA A  1 295 ? 27.04705 25.27336  -23.65160 1.000 14.17683 ? 295 ALA A C   1 
ATOM   2372 O  O   . ALA A  1 295 ? 28.10230 25.26733  -23.01545 1.000 13.65319 ? 295 ALA A O   1 
ATOM   2373 C  CB  . ALA A  1 295 ? 25.67509 23.96234  -22.03420 1.000 10.65229 ? 295 ALA A CB  1 
ATOM   2374 N  N   . GLU A  1 296 ? 27.04003 25.30357  -24.98029 1.000 13.21662 ? 296 GLU A N   1 
ATOM   2375 C  CA  . GLU A  1 296 ? 28.28391 25.40111  -25.72979 1.000 14.78771 ? 296 GLU A CA  1 
ATOM   2376 C  C   . GLU A  1 296 ? 28.80057 26.83355  -25.71910 1.000 11.53184 ? 296 GLU A C   1 
ATOM   2377 O  O   . GLU A  1 296 ? 28.02279 27.79121  -25.77003 1.000 11.54260 ? 296 GLU A O   1 
ATOM   2378 C  CB  . GLU A  1 296 ? 28.08585 24.92597  -27.16839 1.000 11.46277 ? 296 GLU A CB  1 
ATOM   2379 C  CG  . GLU A  1 296 ? 27.99360 23.41955  -27.31236 1.000 10.67379 ? 296 GLU A CG  1 
ATOM   2380 C  CD  . GLU A  1 296 ? 27.98573 22.97716  -28.75965 1.000 17.28957 ? 296 GLU A CD  1 
ATOM   2381 O  OE1 . GLU A  1 296 ? 27.14832 23.48553  -29.53610 1.000 14.45873 ? 296 GLU A OE1 1 
ATOM   2382 O  OE2 . GLU A  1 296 ? 28.82758 22.12927  -29.12381 1.000 17.57462 ? 296 GLU A OE2 1 
ATOM   2383 N  N   . ARG A  1 297 ? 30.12176 26.97465  -25.64598 1.000 7.82746  ? 297 ARG A N   1 
ATOM   2384 C  CA  . ARG A  1 297 ? 30.77500 28.27382  -25.66527 1.000 11.57681 ? 297 ARG A CA  1 
ATOM   2385 C  C   . ARG A  1 297 ? 31.68053 28.37411  -26.88431 1.000 12.74221 ? 297 ARG A C   1 
ATOM   2386 O  O   . ARG A  1 297 ? 32.21838 27.37124  -27.36261 1.000 13.42273 ? 297 ARG A O   1 
ATOM   2387 C  CB  . ARG A  1 297 ? 31.59507 28.52141  -24.38682 1.000 15.16713 ? 297 ARG A CB  1 
ATOM   2388 C  CG  . ARG A  1 297 ? 30.76275 28.73972  -23.12653 1.000 10.64885 ? 297 ARG A CG  1 
ATOM   2389 C  CD  . ARG A  1 297 ? 30.41154 27.42504  -22.45482 1.000 12.87392 ? 297 ARG A CD  1 
ATOM   2390 N  NE  . ARG A  1 297 ? 31.56519 26.81414  -21.80591 1.000 10.99643 ? 297 ARG A NE  1 
ATOM   2391 C  CZ  . ARG A  1 297 ? 31.63821 25.53675  -21.45775 1.000 11.63442 ? 297 ARG A CZ  1 
ATOM   2392 N  NH1 . ARG A  1 297 ? 30.65326 24.69243  -21.71669 1.000 13.21526 ? 297 ARG A NH1 1 
ATOM   2393 N  NH2 . ARG A  1 297 ? 32.73060 25.09304  -20.84252 1.000 13.39257 ? 297 ARG A NH2 1 
ATOM   2394 N  N   . CYS A  1 298 ? 31.84201 29.59688  -27.38637 1.000 13.10068 ? 298 CYS A N   1 
ATOM   2395 C  CA  . CYS A  1 298 ? 32.68865 29.85558  -28.54588 1.000 13.44655 ? 298 CYS A CA  1 
ATOM   2396 C  C   . CYS A  1 298 ? 33.47042 31.13645  -28.30742 1.000 15.73683 ? 298 CYS A C   1 
ATOM   2397 O  O   . CYS A  1 298 ? 32.87697 32.20368  -28.12339 1.000 14.46155 ? 298 CYS A O   1 
ATOM   2398 C  CB  . CYS A  1 298 ? 31.85982 29.96131  -29.82957 1.000 12.53802 ? 298 CYS A CB  1 
ATOM   2399 S  SG  . CYS A  1 298 ? 30.98176 28.44364  -30.26660 1.000 19.46604 ? 298 CYS A SG  1 
ATOM   2400 N  N   . ASP A  1 299 ? 34.79660 31.02383  -28.31035 1.000 16.64974 ? 299 ASP A N   1 
ATOM   2401 C  CA  . ASP A  1 299 ? 35.69892 32.15635  -28.13698 1.000 12.00073 ? 299 ASP A CA  1 
ATOM   2402 C  C   . ASP A  1 299 ? 36.16267 32.59738  -29.52133 1.000 16.30363 ? 299 ASP A C   1 
ATOM   2403 O  O   . ASP A  1 299 ? 36.94641 31.89777  -30.17162 1.000 18.27653 ? 299 ASP A O   1 
ATOM   2404 C  CB  . ASP A  1 299 ? 36.87738 31.76390  -27.24785 1.000 15.82952 ? 299 ASP A CB  1 
ATOM   2405 C  CG  . ASP A  1 299 ? 37.76566 32.93961  -26.89173 1.000 19.90344 ? 299 ASP A CG  1 
ATOM   2406 O  OD1 . ASP A  1 299 ? 37.41543 34.08974  -27.23338 1.000 21.14056 ? 299 ASP A OD1 1 
ATOM   2407 O  OD2 . ASP A  1 299 ? 38.82264 32.70761  -26.26745 1.000 18.43077 ? 299 ASP A OD2 1 
ATOM   2408 N  N   . ILE A  1 300 ? 35.67801 33.75493  -29.97326 1.000 15.14169 ? 300 ILE A N   1 
ATOM   2409 C  CA  . ILE A  1 300 ? 35.89798 34.20275  -31.34176 1.000 18.46569 ? 300 ILE A CA  1 
ATOM   2410 C  C   . ILE A  1 300 ? 36.52408 35.59196  -31.34656 1.000 16.74770 ? 300 ILE A C   1 
ATOM   2411 O  O   . ILE A  1 300 ? 36.37440 36.37680  -30.40698 1.000 13.29140 ? 300 ILE A O   1 
ATOM   2412 C  CB  . ILE A  1 300 ? 34.59142 34.21458  -32.16427 1.000 16.90275 ? 300 ILE A CB  1 
ATOM   2413 C  CG1 . ILE A  1 300 ? 33.65619 35.30482  -31.64577 1.000 17.56459 ? 300 ILE A CG1 1 
ATOM   2414 C  CG2 . ILE A  1 300 ? 33.90674 32.86016  -32.10393 1.000 14.28989 ? 300 ILE A CG2 1 
ATOM   2415 C  CD1 . ILE A  1 300 ? 32.48528 35.58340  -32.54515 1.000 23.67540 ? 300 ILE A CD1 1 
ATOM   2416 N  N   . ILE A  1 301 ? 37.22674 35.88686  -32.43761 1.000 19.93539 ? 301 ILE A N   1 
ATOM   2417 C  CA  . ILE A  1 301 ? 37.78449 37.20633  -32.70904 1.000 14.61969 ? 301 ILE A CA  1 
ATOM   2418 C  C   . ILE A  1 301 ? 37.14031 37.72370  -33.98653 1.000 17.26119 ? 301 ILE A C   1 
ATOM   2419 O  O   . ILE A  1 301 ? 37.07255 37.00061  -34.98715 1.000 16.52588 ? 301 ILE A O   1 
ATOM   2420 C  CB  . ILE A  1 301 ? 39.31764 37.16378  -32.85296 1.000 19.50532 ? 301 ILE A CB  1 
ATOM   2421 C  CG1 . ILE A  1 301 ? 39.95709 36.47818  -31.64389 1.000 18.52493 ? 301 ILE A CG1 1 
ATOM   2422 C  CG2 . ILE A  1 301 ? 39.87422 38.56684  -33.02871 1.000 14.72789 ? 301 ILE A CG2 1 
ATOM   2423 C  CD1 . ILE A  1 301 ? 39.81595 37.25141  -30.35852 1.000 14.82934 ? 301 ILE A CD1 1 
ATOM   2424 N  N   . VAL A  1 302 ? 36.66102 38.96487  -33.95095 1.000 16.99668 ? 302 VAL A N   1 
ATOM   2425 C  CA  . VAL A  1 302 ? 36.00649 39.59013  -35.09386 1.000 16.59893 ? 302 VAL A CA  1 
ATOM   2426 C  C   . VAL A  1 302 ? 36.71080 40.90596  -35.39377 1.000 18.64343 ? 302 VAL A C   1 
ATOM   2427 O  O   . VAL A  1 302 ? 36.95938 41.70427  -34.48329 1.000 22.81186 ? 302 VAL A O   1 
ATOM   2428 C  CB  . VAL A  1 302 ? 34.50450 39.82093  -34.83869 1.000 20.47640 ? 302 VAL A CB  1 
ATOM   2429 C  CG1 . VAL A  1 302 ? 33.86366 40.49188  -36.03688 1.000 17.52364 ? 302 VAL A CG1 1 
ATOM   2430 C  CG2 . VAL A  1 302 ? 33.80987 38.50292  -34.53349 1.000 17.09445 ? 302 VAL A CG2 1 
ATOM   2431 N  N   . ASP A  1 303 ? 37.02542 41.13111  -36.66837 1.000 23.72606 ? 303 ASP A N   1 
ATOM   2432 C  CA  . ASP A  1 303 ? 37.75475 42.31430  -37.11296 1.000 19.95515 ? 303 ASP A CA  1 
ATOM   2433 C  C   . ASP A  1 303 ? 36.77386 43.27395  -37.77994 1.000 21.50574 ? 303 ASP A C   1 
ATOM   2434 O  O   . ASP A  1 303 ? 36.23766 42.97851  -38.85304 1.000 20.57557 ? 303 ASP A O   1 
ATOM   2435 C  CB  . ASP A  1 303 ? 38.87945 41.91941  -38.06903 1.000 16.14965 ? 303 ASP A CB  1 
ATOM   2436 C  CG  . ASP A  1 303 ? 39.83087 43.06540  -38.36528 1.000 24.44465 ? 303 ASP A CG  1 
ATOM   2437 O  OD1 . ASP A  1 303 ? 39.58183 44.19505  -37.89539 1.000 26.28237 ? 303 ASP A OD1 1 
ATOM   2438 O  OD2 . ASP A  1 303 ? 40.83696 42.83251  -39.06749 1.000 27.13529 ? 303 ASP A OD2 1 
ATOM   2439 N  N   . PHE A  1 304 ? 36.54593 44.42396  -37.14683 1.000 25.46124 ? 304 PHE A N   1 
ATOM   2440 C  CA  . PHE A  1 304 ? 35.66738 45.45526  -37.68247 1.000 27.81806 ? 304 PHE A CA  1 
ATOM   2441 C  C   . PHE A  1 304 ? 36.43131 46.61855  -38.30481 1.000 26.52572 ? 304 PHE A C   1 
ATOM   2442 O  O   . PHE A  1 304 ? 35.82995 47.66204  -38.57706 1.000 29.08606 ? 304 PHE A O   1 
ATOM   2443 C  CB  . PHE A  1 304 ? 34.73533 45.98280  -36.58819 1.000 20.14677 ? 304 PHE A CB  1 
ATOM   2444 C  CG  . PHE A  1 304 ? 33.69202 44.99725  -36.14642 1.000 20.91601 ? 304 PHE A CG  1 
ATOM   2445 C  CD1 . PHE A  1 304 ? 32.71241 44.56414  -37.02526 1.000 21.92451 ? 304 PHE A CD1 1 
ATOM   2446 C  CD2 . PHE A  1 304 ? 33.67782 44.51964  -34.84662 1.000 19.16789 ? 304 PHE A CD2 1 
ATOM   2447 C  CE1 . PHE A  1 304 ? 31.74597 43.66153  -36.61992 1.000 22.69938 ? 304 PHE A CE1 1 
ATOM   2448 C  CE2 . PHE A  1 304 ? 32.71283 43.61792  -34.43407 1.000 24.91153 ? 304 PHE A CE2 1 
ATOM   2449 C  CZ  . PHE A  1 304 ? 31.74562 43.18932  -35.32168 1.000 25.09184 ? 304 PHE A CZ  1 
ATOM   2450 N  N   . SER A  1 305 ? 37.73638 46.46076  -38.54391 1.000 24.94213 ? 305 SER A N   1 
ATOM   2451 C  CA  . SER A  1 305 ? 38.54865 47.57947  -39.01762 1.000 29.82767 ? 305 SER A CA  1 
ATOM   2452 C  C   . SER A  1 305 ? 38.09827 48.06089  -40.39206 1.000 29.55723 ? 305 SER A C   1 
ATOM   2453 O  O   . SER A  1 305 ? 38.14477 49.26226  -40.68364 1.000 25.88636 ? 305 SER A O   1 
ATOM   2454 C  CB  . SER A  1 305 ? 40.02299 47.17726  -39.04766 1.000 26.32075 ? 305 SER A CB  1 
ATOM   2455 O  OG  . SER A  1 305 ? 40.20722 45.98116  -39.78595 1.000 29.36855 ? 305 SER A OG  1 
ATOM   2456 N  N   . ARG A  1 306 ? 37.66773 47.13986  -41.25283 1.000 31.69836 ? 306 ARG A N   1 
ATOM   2457 C  CA  . ARG A  1 306 ? 37.18345 47.47493  -42.58420 1.000 28.65250 ? 306 ARG A CA  1 
ATOM   2458 C  C   . ARG A  1 306 ? 35.69451 47.80019  -42.60200 1.000 26.94864 ? 306 ARG A C   1 
ATOM   2459 O  O   . ARG A  1 306 ? 35.06841 47.72503  -43.66534 1.000 29.24608 ? 306 ARG A O   1 
ATOM   2460 C  CB  . ARG A  1 306 ? 37.47506 46.33030  -43.55792 1.000 33.82709 ? 306 ARG A CB  1 
ATOM   2461 C  CG  . ARG A  1 306 ? 38.73034 46.50928  -44.39535 1.000 37.94976 ? 306 ARG A CG  1 
ATOM   2462 C  CD  . ARG A  1 306 ? 39.99769 46.28242  -43.58960 1.000 47.81508 ? 306 ARG A CD  1 
ATOM   2463 N  NE  . ARG A  1 306 ? 41.17545 46.26894  -44.44951 1.000 59.38741 ? 306 ARG A NE  1 
ATOM   2464 C  CZ  . ARG A  1 306 ? 42.42644 46.23738  -44.01113 1.000 60.77554 ? 306 ARG A CZ  1 
ATOM   2465 N  NH1 . ARG A  1 306 ? 42.70592 46.22521  -42.71804 1.000 59.49320 ? 306 ARG A NH1 1 
ATOM   2466 N  NH2 . ARG A  1 306 ? 43.42237 46.22073  -44.89256 1.000 54.26620 ? 306 ARG A NH2 1 
ATOM   2467 N  N   . ALA A  1 307 ? 35.11429 48.16414  -41.45270 1.000 30.77028 ? 307 ALA A N   1 
ATOM   2468 C  CA  . ALA A  1 307 ? 33.67239 48.37153  -41.38227 1.000 30.13342 ? 307 ALA A CA  1 
ATOM   2469 C  C   . ALA A  1 307 ? 33.28148 49.64733  -40.64340 1.000 27.58266 ? 307 ALA A C   1 
ATOM   2470 O  O   . ALA A  1 307 ? 32.16869 49.72208  -40.11198 1.000 28.18603 ? 307 ALA A O   1 
ATOM   2471 C  CB  . ALA A  1 307 ? 32.98691 47.17502  -40.71321 1.000 21.27545 ? 307 ALA A CB  1 
ATOM   2472 N  N   . GLU A  1 308 ? 34.15264 50.65592  -40.60458 1.000 26.86948 ? 308 GLU A N   1 
ATOM   2473 C  CA  . GLU A  1 308 ? 33.83144 51.89585  -39.90762 1.000 25.54583 ? 308 GLU A CA  1 
ATOM   2474 C  C   . GLU A  1 308 ? 32.61754 52.56762  -40.53805 1.000 25.67719 ? 308 GLU A C   1 
ATOM   2475 O  O   . GLU A  1 308 ? 32.61716 52.87697  -41.73325 1.000 28.17498 ? 308 GLU A O   1 
ATOM   2476 C  CB  . GLU A  1 308 ? 35.03418 52.83908  -39.93292 1.000 34.26443 ? 308 GLU A CB  1 
ATOM   2477 C  CG  . GLU A  1 308 ? 34.75900 54.21093  -39.33201 1.000 37.14863 ? 308 GLU A CG  1 
ATOM   2478 C  CD  . GLU A  1 308 ? 35.99533 55.08901  -39.28865 1.000 45.42676 ? 308 GLU A CD  1 
ATOM   2479 O  OE1 . GLU A  1 308 ? 37.07305 54.63385  -39.72975 1.000 49.32200 ? 308 GLU A OE1 1 
ATOM   2480 O  OE2 . GLU A  1 308 ? 35.88788 56.23676  -38.80999 1.000 44.97624 ? 308 GLU A OE2 1 
ATOM   2481 N  N   . GLY A  1 309 ? 31.57915 52.78972  -39.73170 1.000 26.90477 ? 309 GLY A N   1 
ATOM   2482 C  CA  . GLY A  1 309 ? 30.36487 53.43222  -40.18668 1.000 20.89468 ? 309 GLY A CA  1 
ATOM   2483 C  C   . GLY A  1 309 ? 29.25302 52.48859  -40.59327 1.000 24.24714 ? 309 GLY A C   1 
ATOM   2484 O  O   . GLY A  1 309 ? 28.13332 52.95212  -40.84437 1.000 26.19600 ? 309 GLY A O   1 
ATOM   2485 N  N   . LYS A  1 310 ? 29.52000 51.18897  -40.66215 1.000 25.27914 ? 310 LYS A N   1 
ATOM   2486 C  CA  . LYS A  1 310 ? 28.51432 50.22510  -41.07922 1.000 22.84560 ? 310 LYS A CA  1 
ATOM   2487 C  C   . LYS A  1 310 ? 27.71000 49.72242  -39.88333 1.000 23.99095 ? 310 LYS A C   1 
ATOM   2488 O  O   . LYS A  1 310 ? 28.10929 49.86227  -38.72484 1.000 22.21898 ? 310 LYS A O   1 
ATOM   2489 C  CB  . LYS A  1 310 ? 29.16299 49.04474  -41.80424 1.000 19.85066 ? 310 LYS A CB  1 
ATOM   2490 C  CG  . LYS A  1 310 ? 29.86459 49.41626  -43.09985 1.000 28.46211 ? 310 LYS A CG  1 
ATOM   2491 C  CD  . LYS A  1 310 ? 30.39233 48.18051  -43.81253 1.000 34.19088 ? 310 LYS A CD  1 
ATOM   2492 C  CE  . LYS A  1 310 ? 31.13703 48.54823  -45.08584 1.000 31.46500 ? 310 LYS A CE  1 
ATOM   2493 N  NZ  . LYS A  1 310 ? 31.68293 47.34689  -45.77852 1.000 37.04246 ? 310 LYS A NZ  1 
ATOM   2494 N  N   . THR A  1 311 ? 26.55938 49.12946  -40.18576 1.000 22.57209 ? 311 THR A N   1 
ATOM   2495 C  CA  . THR A  1 311 ? 25.67258 48.53842  -39.18739 1.000 26.57729 ? 311 THR A CA  1 
ATOM   2496 C  C   . THR A  1 311 ? 25.65445 47.03160  -39.42722 1.000 30.32950 ? 311 THR A C   1 
ATOM   2497 O  O   . THR A  1 311 ? 25.00591 46.54915  -40.36049 1.000 30.23322 ? 311 THR A O   1 
ATOM   2498 C  CB  . THR A  1 311 ? 24.27155 49.13965  -39.27302 1.000 26.27136 ? 311 THR A CB  1 
ATOM   2499 O  OG1 . THR A  1 311 ? 24.32314 50.53078  -38.93084 1.000 25.30324 ? 311 THR A OG1 1 
ATOM   2500 C  CG2 . THR A  1 311 ? 23.32601 48.42580  -38.32311 1.000 23.18716 ? 311 THR A CG2 1 
ATOM   2501 N  N   . VAL A  1 312 ? 26.37007 46.29304  -38.58457 1.000 24.27298 ? 312 VAL A N   1 
ATOM   2502 C  CA  . VAL A  1 312 ? 26.52209 44.84983  -38.72926 1.000 26.02117 ? 312 VAL A CA  1 
ATOM   2503 C  C   . VAL A  1 312 ? 25.61641 44.16549  -37.71572 1.000 24.17781 ? 312 VAL A C   1 
ATOM   2504 O  O   . VAL A  1 312 ? 25.81044 44.30535  -36.50210 1.000 26.03030 ? 312 VAL A O   1 
ATOM   2505 C  CB  . VAL A  1 312 ? 27.98477 44.41891  -38.54135 1.000 22.08300 ? 312 VAL A CB  1 
ATOM   2506 C  CG1 . VAL A  1 312 ? 28.12238 42.92057  -38.73660 1.000 22.09896 ? 312 VAL A CG1 1 
ATOM   2507 C  CG2 . VAL A  1 312 ? 28.88655 45.17417  -39.50594 1.000 22.34158 ? 312 VAL A CG2 1 
ATOM   2508 N  N   . THR A  1 313 ? 24.63354 43.41922  -38.20975 1.000 22.80479 ? 313 THR A N   1 
ATOM   2509 C  CA  . THR A  1 313 ? 23.68903 42.70513  -37.36262 1.000 20.44704 ? 313 THR A CA  1 
ATOM   2510 C  C   . THR A  1 313 ? 24.12040 41.25150  -37.22362 1.000 19.62268 ? 313 THR A C   1 
ATOM   2511 O  O   . THR A  1 313 ? 24.37367 40.57516  -38.22620 1.000 20.05192 ? 313 THR A O   1 
ATOM   2512 C  CB  . THR A  1 313 ? 22.27353 42.77593  -37.93808 1.000 20.36563 ? 313 THR A CB  1 
ATOM   2513 O  OG1 . THR A  1 313 ? 21.91432 44.14462  -38.16406 1.000 27.27606 ? 313 THR A OG1 1 
ATOM   2514 C  CG2 . THR A  1 313 ? 21.27597 42.15119  -36.97330 1.000 17.17847 ? 313 THR A CG2 1 
ATOM   2515 N  N   . LEU A  1 314 ? 24.21098 40.77917  -35.98310 1.000 16.14622 ? 314 LEU A N   1 
ATOM   2516 C  CA  . LEU A  1 314 ? 24.44713 39.36534  -35.72427 1.000 14.21974 ? 314 LEU A CA  1 
ATOM   2517 C  C   . LEU A  1 314 ? 23.14452 38.60943  -35.94723 1.000 13.20954 ? 314 LEU A C   1 
ATOM   2518 O  O   . LEU A  1 314 ? 22.15295 38.85339  -35.25130 1.000 17.50016 ? 314 LEU A O   1 
ATOM   2519 C  CB  . LEU A  1 314 ? 24.96678 39.15506  -34.30407 1.000 14.72172 ? 314 LEU A CB  1 
ATOM   2520 C  CG  . LEU A  1 314 ? 25.35803 37.72231  -33.93437 1.000 16.44293 ? 314 LEU A CG  1 
ATOM   2521 C  CD1 . LEU A  1 314 ? 26.42254 37.19645  -34.88235 1.000 17.93196 ? 314 LEU A CD1 1 
ATOM   2522 C  CD2 . LEU A  1 314 ? 25.83887 37.64742  -32.49349 1.000 13.57727 ? 314 LEU A CD2 1 
ATOM   2523 N  N   . LYS A  1 315 ? 23.14163 37.70281  -36.91805 1.000 15.53059 ? 315 LYS A N   1 
ATOM   2524 C  CA  . LYS A  1 315 ? 21.92632 37.03968  -37.36164 1.000 18.48198 ? 315 LYS A CA  1 
ATOM   2525 C  C   . LYS A  1 315 ? 21.91627 35.57514  -36.94208 1.000 19.73647 ? 315 LYS A C   1 
ATOM   2526 O  O   . LYS A  1 315 ? 22.95056 34.98478  -36.61959 1.000 17.98540 ? 315 LYS A O   1 
ATOM   2527 C  CB  . LYS A  1 315 ? 21.77412 37.14556  -38.88317 1.000 19.82056 ? 315 LYS A CB  1 
ATOM   2528 C  CG  . LYS A  1 315 ? 21.73616 38.57211  -39.40823 1.000 21.99543 ? 315 LYS A CG  1 
ATOM   2529 C  CD  . LYS A  1 315 ? 20.44302 39.27683  -39.02767 1.000 21.00622 ? 315 LYS A CD  1 
ATOM   2530 C  CE  . LYS A  1 315 ? 19.25835 38.70868  -39.79138 1.000 23.74927 ? 315 LYS A CE  1 
ATOM   2531 N  NZ  . LYS A  1 315 ? 19.44120 38.83520  -41.26237 1.000 22.53324 ? 315 LYS A NZ  1 
ATOM   2532 N  N   . ASN A  1 316 ? 20.71674 34.99935  -36.94880 1.000 19.12036 ? 316 ASN A N   1 
ATOM   2533 C  CA  . ASN A  1 316 ? 20.49536 33.58836  -36.67117 1.000 14.92555 ? 316 ASN A CA  1 
ATOM   2534 C  C   . ASN A  1 316 ? 19.77201 32.96908  -37.85813 1.000 17.89491 ? 316 ASN A C   1 
ATOM   2535 O  O   . ASN A  1 316 ? 18.83120 33.55890  -38.39811 1.000 16.84852 ? 316 ASN A O   1 
ATOM   2536 C  CB  . ASN A  1 316 ? 19.67858 33.39950  -35.38738 1.000 17.72416 ? 316 ASN A CB  1 
ATOM   2537 C  CG  . ASN A  1 316 ? 19.50290 31.93954  -35.01095 1.000 17.45936 ? 316 ASN A CG  1 
ATOM   2538 O  OD1 . ASN A  1 316 ? 20.36557 31.10414  -35.28532 1.000 15.58521 ? 316 ASN A OD1 1 
ATOM   2539 N  ND2 . ASN A  1 316 ? 18.37727 31.62534  -34.37803 1.000 15.08776 ? 316 ASN A ND2 1 
ATOM   2540 N  N   . ARG A  1 317 ? 20.21097 31.78030  -38.26532 1.000 17.44667 ? 317 ARG A N   1 
ATOM   2541 C  CA  . ARG A  1 317 ? 19.72223 31.19441  -39.50703 1.000 16.17158 ? 317 ARG A CA  1 
ATOM   2542 C  C   . ARG A  1 317 ? 18.56384 30.22884  -39.30266 1.000 18.93962 ? 317 ARG A C   1 
ATOM   2543 O  O   . ARG A  1 317 ? 17.67386 30.15028  -40.15995 1.000 18.78056 ? 317 ARG A O   1 
ATOM   2544 C  CB  . ARG A  1 317 ? 20.86827 30.47836  -40.22762 1.000 19.47215 ? 317 ARG A CB  1 
ATOM   2545 C  CG  . ARG A  1 317 ? 20.49221 29.84720  -41.55846 1.000 21.07214 ? 317 ARG A CG  1 
ATOM   2546 C  CD  . ARG A  1 317 ? 21.71792 29.68907  -42.44515 1.000 28.22031 ? 317 ARG A CD  1 
ATOM   2547 N  NE  . ARG A  1 317 ? 21.51642 28.70502  -43.50216 1.000 40.38488 ? 317 ARG A NE  1 
ATOM   2548 C  CZ  . ARG A  1 317 ? 22.42580 28.39400  -44.41617 1.000 41.84108 ? 317 ARG A CZ  1 
ATOM   2549 N  NH1 . ARG A  1 317 ? 23.60437 28.99485  -44.45043 1.000 45.78774 ? 317 ARG A NH1 1 
ATOM   2550 N  NH2 . ARG A  1 317 ? 22.14692 27.45555  -45.31722 1.000 29.11598 ? 317 ARG A NH2 1 
ATOM   2551 N  N   . ILE A  1 318 ? 18.53754 29.50150  -38.18938 1.000 16.25776 ? 318 ILE A N   1 
ATOM   2552 C  CA  . ILE A  1 318 ? 17.56643 28.43241  -37.99544 1.000 13.87674 ? 318 ILE A CA  1 
ATOM   2553 C  C   . ILE A  1 318 ? 16.59034 28.80059  -36.88775 1.000 15.30416 ? 318 ILE A C   1 
ATOM   2554 O  O   . ILE A  1 318 ? 16.90885 29.55593  -35.96284 1.000 16.24746 ? 318 ILE A O   1 
ATOM   2555 C  CB  . ILE A  1 318 ? 18.25618 27.08721  -37.68145 1.000 15.02568 ? 318 ILE A CB  1 
ATOM   2556 C  CG1 . ILE A  1 318 ? 19.11025 27.20447  -36.41888 1.000 13.63999 ? 318 ILE A CG1 1 
ATOM   2557 C  CG2 . ILE A  1 318 ? 19.07722 26.62560  -38.86465 1.000 18.80869 ? 318 ILE A CG2 1 
ATOM   2558 C  CD1 . ILE A  1 318 ? 19.77836 25.92070  -36.00918 1.000 14.60604 ? 318 ILE A CD1 1 
ATOM   2559 N  N   . GLY A  1 319 ? 15.38925 28.24870  -36.98770 1.000 17.05552 ? 319 GLY A N   1 
ATOM   2560 C  CA  . GLY A  1 319 ? 14.39460 28.34938  -35.94406 1.000 15.97450 ? 319 GLY A CA  1 
ATOM   2561 C  C   . GLY A  1 319 ? 14.62452 27.31475  -34.86787 1.000 19.05758 ? 319 GLY A C   1 
ATOM   2562 O  O   . GLY A  1 319 ? 15.74680 26.84118  -34.65291 1.000 23.26216 ? 319 GLY A O   1 
ATOM   2563 N  N   . CYS A  1 320 ? 13.53397 26.94873  -34.19060 1.000 26.21096 ? 320 CYS A N   1 
ATOM   2564 C  CA  . CYS A  1 320 ? 13.57496 26.01176  -33.06898 1.000 24.26762 ? 320 CYS A CA  1 
ATOM   2565 C  C   . CYS A  1 320 ? 13.59231 24.54395  -33.49210 1.000 22.64373 ? 320 CYS A C   1 
ATOM   2566 O  O   . CYS A  1 320 ? 14.09927 23.69573  -32.74328 1.000 18.57957 ? 320 CYS A O   1 
ATOM   2567 C  CB  . CYS A  1 320 ? 12.37464 26.25165  -32.14994 1.000 21.15777 ? 320 CYS A CB  1 
ATOM   2568 S  SG  . CYS A  1 320 ? 12.51286 25.50185  -30.52356 1.000 65.55393 ? 320 CYS A SG  1 
ATOM   2569 N  N   . SER A  1 321 ? 13.02029 24.22112  -34.65296 1.000 26.96016 ? 321 SER A N   1 
ATOM   2570 C  CA  . SER A  1 321 ? 13.05193 22.86852  -35.19523 1.000 20.03749 ? 321 SER A CA  1 
ATOM   2571 C  C   . SER A  1 321 ? 14.00624 22.74541  -36.37344 1.000 19.22467 ? 321 SER A C   1 
ATOM   2572 O  O   . SER A  1 321 ? 13.86040 21.83268  -37.19609 1.000 17.44155 ? 321 SER A O   1 
ATOM   2573 C  CB  . SER A  1 321 ? 11.65400 22.42169  -35.62295 1.000 19.34145 ? 321 SER A CB  1 
ATOM   2574 O  OG  . SER A  1 321 ? 10.71472 22.52253  -34.56955 1.000 26.82959 ? 321 SER A OG  1 
ATOM   2575 N  N   . GLY A  1 322 ? 14.96580 23.65827  -36.48021 1.000 16.52379 ? 322 GLY A N   1 
ATOM   2576 C  CA  . GLY A  1 322 ? 15.89545 23.65992  -37.58240 1.000 17.08295 ? 322 GLY A CA  1 
ATOM   2577 C  C   . GLY A  1 322 ? 15.39480 24.30821  -38.85426 1.000 17.14484 ? 322 GLY A C   1 
ATOM   2578 O  O   . GLY A  1 322 ? 16.16712 24.41431  -39.81469 1.000 19.48865 ? 322 GLY A O   1 
ATOM   2579 N  N   . GLN A  1 323 ? 14.13544 24.73858  -38.90116 1.000 16.87585 ? 323 GLN A N   1 
ATOM   2580 C  CA  . GLN A  1 323 ? 13.60621 25.40754  -40.07872 1.000 17.41922 ? 323 GLN A CA  1 
ATOM   2581 C  C   . GLN A  1 323 ? 14.23197 26.79284  -40.22190 1.000 15.43624 ? 323 GLN A C   1 
ATOM   2582 O  O   . GLN A  1 323 ? 14.95476 27.27086  -39.34500 1.000 18.02868 ? 323 GLN A O   1 
ATOM   2583 C  CB  . GLN A  1 323 ? 12.08260 25.51676  -39.99290 1.000 19.04848 ? 323 GLN A CB  1 
ATOM   2584 C  CG  . GLN A  1 323 ? 11.56884 26.60401  -39.04183 1.000 17.15940 ? 323 GLN A CG  1 
ATOM   2585 C  CD  . GLN A  1 323 ? 11.62402 26.20591  -37.57426 1.000 22.85403 ? 323 GLN A CD  1 
ATOM   2586 O  OE1 . GLN A  1 323 ? 12.62627 25.67445  -37.09639 1.000 28.41854 ? 323 GLN A OE1 1 
ATOM   2587 N  NE2 . GLN A  1 323 ? 10.53910 26.46520  -36.85149 1.000 19.09310 ? 323 GLN A NE2 1 
ATOM   2588 N  N   . ASP A  1 324 ? 13.94783 27.44132  -41.34978 1.000 15.14183 ? 324 ASP A N   1 
ATOM   2589 C  CA  . ASP A  1 324 ? 14.43386 28.79798  -41.56417 1.000 17.97019 ? 324 ASP A CA  1 
ATOM   2590 C  C   . ASP A  1 324 ? 13.88544 29.72892  -40.49271 1.000 17.60210 ? 324 ASP A C   1 
ATOM   2591 O  O   . ASP A  1 324 ? 12.67461 29.78288  -40.25810 1.000 22.18211 ? 324 ASP A O   1 
ATOM   2592 C  CB  . ASP A  1 324 ? 14.03716 29.29650  -42.95314 1.000 15.24400 ? 324 ASP A CB  1 
ATOM   2593 C  CG  . ASP A  1 324 ? 15.05259 28.92628  -44.01348 1.000 17.08921 ? 324 ASP A CG  1 
ATOM   2594 O  OD1 . ASP A  1 324 ? 16.09698 28.34469  -43.65337 1.000 15.21422 ? 324 ASP A OD1 1 
ATOM   2595 O  OD2 . ASP A  1 324 ? 14.81080 29.21787  -45.20373 1.000 19.28022 ? 324 ASP A OD2 1 
ATOM   2596 N  N   . ALA A  1 325 ? 14.78655 30.45372  -39.83591 1.000 16.19730 ? 325 ALA A N   1 
ATOM   2597 C  CA  . ALA A  1 325 ? 14.38105 31.36602  -38.77852 1.000 17.01189 ? 325 ALA A CA  1 
ATOM   2598 C  C   . ALA A  1 325 ? 13.48197 32.46170  -39.33271 1.000 21.03857 ? 325 ALA A C   1 
ATOM   2599 O  O   . ALA A  1 325 ? 13.73746 33.01926  -40.40382 1.000 18.59701 ? 325 ALA A O   1 
ATOM   2600 C  CB  . ALA A  1 325 ? 15.60943 31.98355  -38.11084 1.000 17.41670 ? 325 ALA A CB  1 
ATOM   2601 N  N   . ASP A  1 326 ? 12.41102 32.75241  -38.60612 1.000 23.72971 ? 326 ASP A N   1 
ATOM   2602 C  CA  . ASP A  1 326 ? 11.59261 33.90261  -38.94385 1.000 26.72394 ? 326 ASP A CA  1 
ATOM   2603 C  C   . ASP A  1 326 ? 12.41070 35.17381  -38.73859 1.000 24.86114 ? 326 ASP A C   1 
ATOM   2604 O  O   . ASP A  1 326 ? 13.18379 35.26471  -37.78098 1.000 32.63481 ? 326 ASP A O   1 
ATOM   2605 C  CB  . ASP A  1 326 ? 10.33089 33.93478  -38.07727 1.000 27.56031 ? 326 ASP A CB  1 
ATOM   2606 C  CG  . ASP A  1 326 ? 9.36154  35.04024  -38.47761 1.000 36.21116 ? 326 ASP A CG  1 
ATOM   2607 O  OD1 . ASP A  1 326 ? 9.71592  36.23321  -38.37080 1.000 36.40051 ? 326 ASP A OD1 1 
ATOM   2608 O  OD2 . ASP A  1 326 ? 8.23372  34.71194  -38.90166 1.000 52.36517 ? 326 ASP A OD2 1 
ATOM   2609 N  N   . PRO A  1 327 ? 12.27817 36.16550  -39.61662 1.000 28.50207 ? 327 PRO A N   1 
ATOM   2610 C  CA  . PRO A  1 327 ? 12.96883 37.44379  -39.38432 1.000 25.28870 ? 327 PRO A CA  1 
ATOM   2611 C  C   . PRO A  1 327 ? 12.53990 38.14745  -38.09974 1.000 37.72577 ? 327 PRO A C   1 
ATOM   2612 O  O   . PRO A  1 327 ? 12.35077 39.36808  -38.08711 1.000 33.51525 ? 327 PRO A O   1 
ATOM   2613 C  CB  . PRO A  1 327 ? 12.60332 38.26381  -40.62718 1.000 27.52484 ? 327 PRO A CB  1 
ATOM   2614 C  CG  . PRO A  1 327 ? 12.36923 37.23058  -41.68929 1.000 18.78634 ? 327 PRO A CG  1 
ATOM   2615 C  CD  . PRO A  1 327 ? 11.71492 36.07815  -40.97594 1.000 27.08614 ? 327 PRO A CD  1 
ATOM   2616 N  N   . THR A  1 329 ? 12.37120 37.38103  -37.01806 1.000 41.04599 ? 328 THR A N   1 
ATOM   2617 C  CA  . THR A  1 329 ? 12.23350 37.91793  -35.66959 1.000 28.39234 ? 328 THR A CA  1 
ATOM   2618 C  C   . THR A  1 329 ? 13.24105 37.22060  -34.75981 1.000 23.93546 ? 328 THR A C   1 
ATOM   2619 O  O   . THR A  1 329 ? 14.01461 37.88472  -34.06386 1.000 27.88676 ? 328 THR A O   1 
ATOM   2620 C  CB  . THR A  1 329 ? 10.79679 37.76652  -35.14328 1.000 32.30862 ? 328 THR A CB  1 
ATOM   2621 O  OG1 . THR A  1 329 ? 10.74276 38.15996  -33.76676 1.000 33.83220 ? 328 THR A OG1 1 
ATOM   2622 C  CG2 . THR A  1 329 ? 10.28391 36.33492  -35.27842 1.000 29.29634 ? 328 THR A CG2 1 
ATOM   2623 N  N   . ASP A  1 330 ? 13.26276 35.88784  -34.77409 1.000 25.40329 ? 329 ASP A N   1 
ATOM   2624 C  CA  . ASP A  1 330 ? 14.31155 35.12858  -34.10800 1.000 18.19474 ? 329 ASP A CA  1 
ATOM   2625 C  C   . ASP A  1 330 ? 15.52714 34.91971  -34.99983 1.000 18.34638 ? 329 ASP A C   1 
ATOM   2626 O  O   . ASP A  1 330 ? 16.48166 34.25654  -34.58029 1.000 19.97179 ? 329 ASP A O   1 
ATOM   2627 C  CB  . ASP A  1 330 ? 13.77516 33.77412  -33.62064 1.000 21.45098 ? 329 ASP A CB  1 
ATOM   2628 C  CG  . ASP A  1 330 ? 13.35614 32.85780  -34.75741 1.000 23.33942 ? 329 ASP A CG  1 
ATOM   2629 O  OD1 . ASP A  1 330 ? 12.94364 33.36665  -35.81908 1.000 22.47325 ? 329 ASP A OD1 1 
ATOM   2630 O  OD2 . ASP A  1 330 ? 13.43221 31.62149  -34.58312 1.000 18.90737 ? 329 ASP A OD2 1 
ATOM   2631 N  N   . ALA A  1 331 ? 15.50771 35.46121  -36.21893 1.000 21.59674 ? 330 ALA A N   1 
ATOM   2632 C  CA  . ALA A  1 331 ? 16.68243 35.50787  -37.07940 1.000 19.84075 ? 330 ALA A CA  1 
ATOM   2633 C  C   . ALA A  1 331 ? 17.64590 36.60814  -36.67530 1.000 21.87749 ? 330 ALA A C   1 
ATOM   2634 O  O   . ALA A  1 331 ? 18.71641 36.73327  -37.28175 1.000 21.42400 ? 330 ALA A O   1 
ATOM   2635 C  CB  . ALA A  1 331 ? 16.26762 35.70500  -38.53910 1.000 14.58638 ? 330 ALA A CB  1 
ATOM   2636 N  N   . ASN A  1 332 ? 17.28491 37.40842  -35.68064 1.000 17.78005 ? 331 ASN A N   1 
ATOM   2637 C  CA  . ASN A  1 332 ? 18.13331 38.47353  -35.17212 1.000 15.66787 ? 331 ASN A CA  1 
ATOM   2638 C  C   . ASN A  1 332 ? 18.58870 38.15146  -33.75393 1.000 16.47842 ? 331 ASN A C   1 
ATOM   2639 O  O   . ASN A  1 332 ? 17.79251 37.75595  -32.90171 1.000 17.90520 ? 331 ASN A O   1 
ATOM   2640 C  CB  . ASN A  1 332 ? 17.39625 39.80880  -35.18171 1.000 16.59926 ? 331 ASN A CB  1 
ATOM   2641 C  CG  . ASN A  1 332 ? 16.66520 40.05628  -36.48590 1.000 17.23431 ? 331 ASN A CG  1 
ATOM   2642 O  OD1 . ASN A  1 332 ? 17.25237 40.51569  -37.46539 1.000 19.80979 ? 331 ASN A OD1 1 
ATOM   2643 N  ND2 . ASN A  1 332 ? 15.37233 39.75508  -36.50373 1.000 18.38054 ? 331 ASN A ND2 1 
ATOM   2644 N  N   . ILE A  1 333 ? 19.88420 38.34750  -33.51816 1.000 13.63038 ? 332 ILE A N   1 
ATOM   2645 C  CA  . ILE A  1 333 ? 20.48517 38.25450  -32.18888 1.000 18.60579 ? 332 ILE A CA  1 
ATOM   2646 C  C   . ILE A  1 333 ? 20.70171 39.64157  -31.58321 1.000 20.81865 ? 332 ILE A C   1 
ATOM   2647 O  O   . ILE A  1 333 ? 20.11970 39.97096  -30.55202 1.000 17.30141 ? 332 ILE A O   1 
ATOM   2648 C  CB  . ILE A  1 333 ? 21.80321 37.44940  -32.22922 1.000 16.59944 ? 332 ILE A CB  1 
ATOM   2649 C  CG1 . ILE A  1 333 ? 21.59174 36.09207  -32.87609 1.000 12.73288 ? 332 ILE A CG1 1 
ATOM   2650 C  CG2 . ILE A  1 333 ? 22.36869 37.28528  -30.81523 1.000 15.38532 ? 332 ILE A CG2 1 
ATOM   2651 C  CD1 . ILE A  1 333 ? 20.61068 35.20246  -32.11325 1.000 11.30127 ? 332 ILE A CD1 1 
ATOM   2652 N  N   . MET A  1 334 ? 21.55806 40.45698  -32.19975 1.000 20.79936 ? 333 MET A N   1 
ATOM   2653 C  CA  . MET A  1 334 ? 21.77918 41.82922  -31.76450 1.000 19.71934 ? 333 MET A CA  1 
ATOM   2654 C  C   . MET A  1 334 ? 22.43526 42.58740  -32.90684 1.000 20.83518 ? 333 MET A C   1 
ATOM   2655 O  O   . MET A  1 334 ? 22.79898 42.00619  -33.92908 1.000 19.81836 ? 333 MET A O   1 
ATOM   2656 C  CB  . MET A  1 334 ? 22.64135 41.90349  -30.50112 1.000 16.81867 ? 333 MET A CB  1 
ATOM   2657 C  CG  . MET A  1 334 ? 23.93807 41.15006  -30.60032 1.000 15.62275 ? 333 MET A CG  1 
ATOM   2658 S  SD  . MET A  1 334 ? 25.06771 41.61985  -29.28961 1.000 22.78460 ? 333 MET A SD  1 
ATOM   2659 C  CE  . MET A  1 334 ? 24.99443 43.39488  -29.46955 1.000 16.33171 ? 333 MET A CE  1 
ATOM   2660 N  N   . GLN A  1 335 ? 22.58600 43.89702  -32.72815 1.000 17.03823 ? 334 GLN A N   1 
ATOM   2661 C  CA  . GLN A  1 335 ? 23.04956 44.75435  -33.81007 1.000 23.15248 ? 334 GLN A CA  1 
ATOM   2662 C  C   . GLN A  1 335 ? 24.26812 45.53992  -33.35452 1.000 24.01637 ? 334 GLN A C   1 
ATOM   2663 O  O   . GLN A  1 335 ? 24.23806 46.17310  -32.29670 1.000 22.36228 ? 334 GLN A O   1 
ATOM   2664 C  CB  . GLN A  1 335 ? 21.93479 45.70298  -34.26743 1.000 21.60591 ? 334 GLN A CB  1 
ATOM   2665 C  CG  . GLN A  1 335 ? 22.36721 46.76428  -35.24535 1.000 26.09501 ? 334 GLN A CG  1 
ATOM   2666 C  CD  . GLN A  1 335 ? 21.19138 47.54431  -35.78944 1.000 31.65388 ? 334 GLN A CD  1 
ATOM   2667 O  OE1 . GLN A  1 335 ? 21.00943 48.71936  -35.47062 1.000 28.99133 ? 334 GLN A OE1 1 
ATOM   2668 N  NE2 . GLN A  1 335 ? 20.38690 46.89460  -36.62296 1.000 31.31041 ? 334 GLN A NE2 1 
ATOM   2669 N  N   . PHE A  1 336 ? 25.34421 45.48086  -34.13373 1.000 19.48877 ? 335 PHE A N   1 
ATOM   2670 C  CA  . PHE A  1 336 ? 26.56092 46.22415  -33.83353 1.000 20.63924 ? 335 PHE A CA  1 
ATOM   2671 C  C   . PHE A  1 336 ? 26.65213 47.43371  -34.75271 1.000 23.68045 ? 335 PHE A C   1 
ATOM   2672 O  O   . PHE A  1 336 ? 26.47382 47.30973  -35.96874 1.000 25.10535 ? 335 PHE A O   1 
ATOM   2673 C  CB  . PHE A  1 336 ? 27.79940 45.34197  -33.99089 1.000 20.79322 ? 335 PHE A CB  1 
ATOM   2674 C  CG  . PHE A  1 336 ? 27.86756 44.21188  -33.00446 1.000 25.96248 ? 335 PHE A CG  1 
ATOM   2675 C  CD1 . PHE A  1 336 ? 28.27566 44.43813  -31.70060 1.000 23.74019 ? 335 PHE A CD1 1 
ATOM   2676 C  CD2 . PHE A  1 336 ? 27.53194 42.92287  -33.38218 1.000 21.48817 ? 335 PHE A CD2 1 
ATOM   2677 C  CE1 . PHE A  1 336 ? 28.34590 43.40222  -30.79160 1.000 17.81595 ? 335 PHE A CE1 1 
ATOM   2678 C  CE2 . PHE A  1 336 ? 27.59934 41.88302  -32.47808 1.000 20.93937 ? 335 PHE A CE2 1 
ATOM   2679 C  CZ  . PHE A  1 336 ? 28.00781 42.12310  -31.18066 1.000 23.38549 ? 335 PHE A CZ  1 
ATOM   2680 N  N   . ARG A  1 337 ? 26.92266 48.59864  -34.16971 1.000 22.08724 ? 336 ARG A N   1 
ATOM   2681 C  CA  . ARG A  1 337 ? 27.04410 49.84864  -34.91263 1.000 18.88280 ? 336 ARG A CA  1 
ATOM   2682 C  C   . ARG A  1 337 ? 28.47683 50.34377  -34.77412 1.000 21.66508 ? 336 ARG A C   1 
ATOM   2683 O  O   . ARG A  1 337 ? 28.87723 50.80947  -33.70179 1.000 22.77463 ? 336 ARG A O   1 
ATOM   2684 C  CB  . ARG A  1 337 ? 26.04220 50.88362  -34.40417 1.000 20.55714 ? 336 ARG A CB  1 
ATOM   2685 C  CG  . ARG A  1 337 ? 24.59715 50.42545  -34.51833 1.000 20.64000 ? 336 ARG A CG  1 
ATOM   2686 C  CD  . ARG A  1 337 ? 23.65466 51.29959  -33.71014 1.000 29.84046 ? 336 ARG A CD  1 
ATOM   2687 N  NE  . ARG A  1 337 ? 22.31006 50.73623  -33.67097 1.000 30.05429 ? 336 ARG A NE  1 
ATOM   2688 C  CZ  . ARG A  1 337 ? 21.31144 51.22238  -32.94664 1.000 27.88806 ? 336 ARG A CZ  1 
ATOM   2689 N  NH1 . ARG A  1 337 ? 21.46742 52.29191  -32.18273 1.000 21.80117 ? 336 ARG A NH1 1 
ATOM   2690 N  NH2 . ARG A  1 337 ? 20.12678 50.61852  -32.98796 1.000 28.76623 ? 336 ARG A NH2 1 
ATOM   2691 N  N   . ILE A  1 338 ? 29.24478 50.24513  -35.85797 1.000 22.32745 ? 337 ILE A N   1 
ATOM   2692 C  CA  . ILE A  1 338 ? 30.65960 50.60048  -35.84260 1.000 23.11736 ? 337 ILE A CA  1 
ATOM   2693 C  C   . ILE A  1 338 ? 30.80044 52.11303  -35.95800 1.000 25.24231 ? 337 ILE A C   1 
ATOM   2694 O  O   . ILE A  1 338 ? 31.37016 52.62490  -36.92853 1.000 22.05983 ? 337 ILE A O   1 
ATOM   2695 C  CB  . ILE A  1 338 ? 31.42211 49.88301  -36.97152 1.000 23.09819 ? 337 ILE A CB  1 
ATOM   2696 C  CG1 . ILE A  1 338 ? 30.89236 48.45902  -37.15258 1.000 18.88601 ? 337 ILE A CG1 1 
ATOM   2697 C  CG2 . ILE A  1 338 ? 32.91411 49.84953  -36.67375 1.000 24.11386 ? 337 ILE A CG2 1 
ATOM   2698 C  CD1 . ILE A  1 338 ? 31.11989 47.56287  -35.95546 1.000 20.59306 ? 337 ILE A CD1 1 
ATOM   2699 N  N   . SER A  1 339 ? 30.28575 52.83930  -34.96331 1.000 28.36247 ? 338 SER A N   1 
ATOM   2700 C  CA  . SER A  1 339 ? 30.29059 54.29389  -34.98627 1.000 26.92627 ? 338 SER A CA  1 
ATOM   2701 C  C   . SER A  1 339 ? 31.18127 54.92613  -33.92769 1.000 34.79428 ? 338 SER A C   1 
ATOM   2702 O  O   . SER A  1 339 ? 31.49831 56.11400  -34.04691 1.000 31.75188 ? 338 SER A O   1 
ATOM   2703 C  CB  . SER A  1 339 ? 28.86251 54.83324  -34.81761 1.000 23.44868 ? 338 SER A CB  1 
ATOM   2704 O  OG  . SER A  1 339 ? 28.27722 54.35808  -33.61814 1.000 26.81454 ? 338 SER A OG  1 
ATOM   2705 N  N   . LYS A  1 340 ? 31.58354 54.18003  -32.90472 1.000 30.19612 ? 339 LYS A N   1 
ATOM   2706 C  CA  . LYS A  1 340 ? 32.48440 54.73155  -31.90002 1.000 32.30926 ? 339 LYS A CA  1 
ATOM   2707 C  C   . LYS A  1 340 ? 33.83900 55.02448  -32.53389 1.000 32.25245 ? 339 LYS A C   1 
ATOM   2708 O  O   . LYS A  1 340 ? 34.39056 54.16441  -33.23070 1.000 31.60282 ? 339 LYS A O   1 
ATOM   2709 C  CB  . LYS A  1 340 ? 32.65031 53.77004  -30.72476 1.000 31.54229 ? 339 LYS A CB  1 
ATOM   2710 C  CG  . LYS A  1 340 ? 31.86352 54.16299  -29.48250 1.000 34.90407 ? 339 LYS A CG  1 
ATOM   2711 C  CD  . LYS A  1 340 ? 32.21931 53.28028  -28.29381 1.000 29.63286 ? 339 LYS A CD  1 
ATOM   2712 C  CE  . LYS A  1 340 ? 33.68670 53.42143  -27.91607 1.000 43.04846 ? 339 LYS A CE  1 
ATOM   2713 N  NZ  . LYS A  1 340 ? 34.05574 52.54926  -26.76440 1.000 38.10755 ? 339 LYS A NZ  1 
ATOM   2714 N  N   . PRO A  1 341 ? 34.39937 56.21320  -32.32993 1.000 36.34075 ? 340 PRO A N   1 
ATOM   2715 C  CA  . PRO A  1 341 ? 35.70620 56.51673  -32.91831 1.000 33.85088 ? 340 PRO A CA  1 
ATOM   2716 C  C   . PRO A  1 341 ? 36.80273 55.67451  -32.28896 1.000 39.53230 ? 340 PRO A C   1 
ATOM   2717 O  O   . PRO A  1 341 ? 36.75269 55.32251  -31.10743 1.000 34.86811 ? 340 PRO A O   1 
ATOM   2718 C  CB  . PRO A  1 341 ? 35.89817 58.00519  -32.60814 1.000 29.16199 ? 340 PRO A CB  1 
ATOM   2719 C  CG  . PRO A  1 341 ? 35.07151 58.23609  -31.38555 1.000 29.60226 ? 340 PRO A CG  1 
ATOM   2720 C  CD  . PRO A  1 341 ? 33.87779 57.33173  -31.52556 1.000 35.68030 ? 340 PRO A CD  1 
ATOM   2721 N  N   . LEU A  1 342 ? 37.79944 55.34367  -33.10442 1.000 30.90964 ? 341 LEU A N   1 
ATOM   2722 C  CA  . LEU A  1 342 ? 38.92638 54.53962  -32.64652 1.000 27.89566 ? 341 LEU A CA  1 
ATOM   2723 C  C   . LEU A  1 342 ? 39.73740 55.33982  -31.63426 1.000 36.43793 ? 341 LEU A C   1 
ATOM   2724 O  O   . LEU A  1 342 ? 40.43445 56.29081  -32.00179 1.000 41.77032 ? 341 LEU A O   1 
ATOM   2725 C  CB  . LEU A  1 342 ? 39.78502 54.12340  -33.83634 1.000 25.63497 ? 341 LEU A CB  1 
ATOM   2726 C  CG  . LEU A  1 342 ? 40.94791 53.17178  -33.56060 1.000 28.61007 ? 341 LEU A CG  1 
ATOM   2727 C  CD1 . LEU A  1 342 ? 40.43983 51.84049  -33.02355 1.000 26.73104 ? 341 LEU A CD1 1 
ATOM   2728 C  CD2 . LEU A  1 342 ? 41.77260 52.96744  -34.82010 1.000 25.77898 ? 341 LEU A CD2 1 
ATOM   2729 N  N   . LYS A  1 343 ? 39.63797 54.96607  -30.35662 1.000 38.17785 ? 342 LYS A N   1 
ATOM   2730 C  CA  . LYS A  1 343 ? 40.38281 55.63864  -29.29749 1.000 39.26607 ? 342 LYS A CA  1 
ATOM   2731 C  C   . LYS A  1 343 ? 41.88144 55.53439  -29.54684 1.000 37.18156 ? 342 LYS A C   1 
ATOM   2732 O  O   . LYS A  1 343 ? 42.50219 56.47331  -30.05608 1.000 43.47626 ? 342 LYS A O   1 
ATOM   2733 C  CB  . LYS A  1 343 ? 40.03888 55.04751  -27.92667 1.000 32.88481 ? 342 LYS A CB  1 
ATOM   2734 C  CG  . LYS A  1 343 ? 38.59922 55.25158  -27.48697 1.000 35.92112 ? 342 LYS A CG  1 
ATOM   2735 C  CD  . LYS A  1 343 ? 38.38422 54.73962  -26.06979 1.000 47.95091 ? 342 LYS A CD  1 
ATOM   2736 C  CE  . LYS A  1 343 ? 36.91551 54.78288  -25.68501 1.000 43.69275 ? 342 LYS A CE  1 
ATOM   2737 N  NZ  . LYS A  1 343 ? 36.72601 54.67188  -24.21109 1.000 33.00303 ? 342 LYS A NZ  1 
ATOM   2738 N  N   . GLN A  1 344 ? 42.46739 54.39967  -29.18674 1.000 32.16760 ? 343 GLN A N   1 
ATOM   2739 C  CA  . GLN A  1 344 ? 43.87268 54.12668  -29.43747 1.000 33.16305 ? 343 GLN A CA  1 
ATOM   2740 C  C   . GLN A  1 344 ? 44.01412 53.19156  -30.63309 1.000 31.43034 ? 343 GLN A C   1 
ATOM   2741 O  O   . GLN A  1 344 ? 43.04215 52.61268  -31.12214 1.000 34.71488 ? 343 GLN A O   1 
ATOM   2742 C  CB  . GLN A  1 344 ? 44.52990 53.51455  -28.19710 1.000 34.12036 ? 343 GLN A CB  1 
ATOM   2743 C  CG  . GLN A  1 344 ? 44.15611 54.20348  -26.89584 1.000 33.77326 ? 343 GLN A CG  1 
ATOM   2744 C  CD  . GLN A  1 344 ? 44.77070 53.53267  -25.68362 1.000 38.51560 ? 343 GLN A CD  1 
ATOM   2745 O  OE1 . GLN A  1 344 ? 45.75213 52.79774  -25.79694 1.000 44.24249 ? 343 GLN A OE1 1 
ATOM   2746 N  NE2 . GLN A  1 344 ? 44.19206 53.77981  -24.51357 1.000 33.88452 ? 343 GLN A NE2 1 
ATOM   2747 N  N   . LYS A  1 345 ? 45.24790 53.05176  -31.10775 1.000 31.73160 ? 344 LYS A N   1 
ATOM   2748 C  CA  . LYS A  1 345 ? 45.52278 52.10650  -32.18016 1.000 33.54799 ? 344 LYS A CA  1 
ATOM   2749 C  C   . LYS A  1 345 ? 45.30857 50.68121  -31.68573 1.000 36.90404 ? 344 LYS A C   1 
ATOM   2750 O  O   . LYS A  1 345 ? 45.74611 50.32020  -30.58857 1.000 41.72513 ? 344 LYS A O   1 
ATOM   2751 C  CB  . LYS A  1 345 ? 46.95005 52.28118  -32.69708 1.000 31.01188 ? 344 LYS A CB  1 
ATOM   2752 C  CG  . LYS A  1 345 ? 47.54699 51.00569  -33.26493 1.000 29.47816 ? 344 LYS A CG  1 
ATOM   2753 C  CD  . LYS A  1 345 ? 48.40721 51.26681  -34.48338 1.000 33.77583 ? 344 LYS A CD  1 
ATOM   2754 C  CE  . LYS A  1 345 ? 48.85037 49.95547  -35.11007 1.000 41.91588 ? 344 LYS A CE  1 
ATOM   2755 N  NZ  . LYS A  1 345 ? 49.54901 50.16890  -36.40313 1.000 42.21249 ? 344 LYS A NZ  1 
ATOM   2756 N  N   . ASP A  1 346 ? 44.62486 49.87365  -32.49187 1.000 35.72391 ? 345 ASP A N   1 
ATOM   2757 C  CA  . ASP A  1 346 ? 44.38325 48.47410  -32.15069 1.000 34.51884 ? 345 ASP A CA  1 
ATOM   2758 C  C   . ASP A  1 346 ? 45.68435 47.69840  -32.30059 1.000 30.23935 ? 345 ASP A C   1 
ATOM   2759 O  O   . ASP A  1 346 ? 46.08978 47.34533  -33.40990 1.000 25.51602 ? 345 ASP A O   1 
ATOM   2760 C  CB  . ASP A  1 346 ? 43.29113 47.88660  -33.03606 1.000 25.80553 ? 345 ASP A CB  1 
ATOM   2761 C  CG  . ASP A  1 346 ? 42.99691 46.43297  -32.71295 1.000 27.21433 ? 345 ASP A CG  1 
ATOM   2762 O  OD1 . ASP A  1 346 ? 43.39233 45.96786  -31.62256 1.000 22.40838 ? 345 ASP A OD1 1 
ATOM   2763 O  OD2 . ASP A  1 346 ? 42.37511 45.75161  -33.55532 1.000 30.23309 ? 345 ASP A OD2 1 
ATOM   2764 N  N   . THR A  1 347 ? 46.34482 47.42814  -31.17746 1.000 32.21437 ? 346 THR A N   1 
ATOM   2765 C  CA  . THR A  1 347 ? 47.55272 46.61756  -31.15695 1.000 30.61443 ? 346 THR A CA  1 
ATOM   2766 C  C   . THR A  1 347 ? 47.29482 45.19965  -30.66326 1.000 30.47654 ? 346 THR A C   1 
ATOM   2767 O  O   . THR A  1 347 ? 48.25050 44.46089  -30.40657 1.000 31.68878 ? 346 THR A O   1 
ATOM   2768 C  CB  . THR A  1 347 ? 48.62765 47.28725  -30.29723 1.000 32.84914 ? 346 THR A CB  1 
ATOM   2769 O  OG1 . THR A  1 347 ? 48.03125 47.82525  -29.10996 1.000 29.84350 ? 346 THR A OG1 1 
ATOM   2770 C  CG2 . THR A  1 347 ? 49.30916 48.40413  -31.07337 1.000 33.09819 ? 346 THR A CG2 1 
ATOM   2771 N  N   . SER A  1 348 ? 46.03070 44.80562  -30.52291 1.000 31.30697 ? 347 SER A N   1 
ATOM   2772 C  CA  . SER A  1 348 ? 45.70899 43.43423  -30.16154 1.000 26.75851 ? 347 SER A CA  1 
ATOM   2773 C  C   . SER A  1 348 ? 46.14229 42.48143  -31.27310 1.000 25.86903 ? 347 SER A C   1 
ATOM   2774 O  O   . SER A  1 348 ? 46.37418 42.88186  -32.41757 1.000 23.55182 ? 347 SER A O   1 
ATOM   2775 C  CB  . SER A  1 348 ? 44.21258 43.28676  -29.88312 1.000 25.26575 ? 347 SER A CB  1 
ATOM   2776 O  OG  . SER A  1 348 ? 43.43917 43.69837  -30.99630 1.000 24.56252 ? 347 SER A OG  1 
ATOM   2777 N  N   . SER A  1 349 ? 46.24922 41.20211  -30.92506 1.000 21.80070 ? 348 SER A N   1 
ATOM   2778 C  CA  . SER A  1 349 ? 46.84986 40.21405  -31.80688 1.000 27.06342 ? 348 SER A CA  1 
ATOM   2779 C  C   . SER A  1 349 ? 45.88174 39.08059  -32.11719 1.000 24.13469 ? 348 SER A C   1 
ATOM   2780 O  O   . SER A  1 349 ? 45.00121 38.74928  -31.31777 1.000 26.19368 ? 348 SER A O   1 
ATOM   2781 C  CB  . SER A  1 349 ? 48.12798 39.63618  -31.19077 1.000 26.53610 ? 348 SER A CB  1 
ATOM   2782 O  OG  . SER A  1 349 ? 49.07648 40.65804  -30.94182 1.000 25.22663 ? 348 SER A OG  1 
ATOM   2783 N  N   . LEU A  1 350 ? 46.06328 38.49192  -33.30207 1.000 25.75358 ? 349 LEU A N   1 
ATOM   2784 C  CA  . LEU A  1 350 ? 45.39655 37.26071  -33.72047 1.000 22.45719 ? 349 LEU A CA  1 
ATOM   2785 C  C   . LEU A  1 350 ? 46.50830 36.27943  -34.07788 1.000 21.01980 ? 349 LEU A C   1 
ATOM   2786 O  O   . LEU A  1 350 ? 46.79952 36.05749  -35.26260 1.000 27.13306 ? 349 LEU A O   1 
ATOM   2787 C  CB  . LEU A  1 350 ? 44.44754 37.50827  -34.89401 1.000 24.42582 ? 349 LEU A CB  1 
ATOM   2788 C  CG  . LEU A  1 350 ? 43.36250 36.47802  -35.23698 1.000 22.54776 ? 349 LEU A CG  1 
ATOM   2789 C  CD1 . LEU A  1 350 ? 43.87739 35.38488  -36.16387 1.000 33.03943 ? 349 LEU A CD1 1 
ATOM   2790 C  CD2 . LEU A  1 350 ? 42.77940 35.87142  -33.97050 1.000 22.69286 ? 349 LEU A CD2 1 
ATOM   2791 N  N   . PRO A  1 351 ? 47.16712 35.69171  -33.08080 1.000 28.84794 ? 350 PRO A N   1 
ATOM   2792 C  CA  . PRO A  1 351 ? 48.35959 34.88467  -33.36230 1.000 30.89869 ? 350 PRO A CA  1 
ATOM   2793 C  C   . PRO A  1 351 ? 48.02488 33.57967  -34.06634 1.000 27.79294 ? 350 PRO A C   1 
ATOM   2794 O  O   . PRO A  1 351 ? 46.93642 33.02013  -33.91548 1.000 22.85201 ? 350 PRO A O   1 
ATOM   2795 C  CB  . PRO A  1 351 ? 48.95182 34.62883  -31.97124 1.000 22.88106 ? 350 PRO A CB  1 
ATOM   2796 C  CG  . PRO A  1 351 ? 47.80163 34.75951  -31.04150 1.000 18.03158 ? 350 PRO A CG  1 
ATOM   2797 C  CD  . PRO A  1 351 ? 46.88933 35.79027  -31.63727 1.000 20.71180 ? 350 PRO A CD  1 
ATOM   2798 N  N   . ARG A  1 352 ? 48.99468 33.09650  -34.84748 1.000 33.15127 ? 351 ARG A N   1 
ATOM   2799 C  CA  . ARG A  1 352 ? 48.81091 31.84853  -35.58183 1.000 34.91147 ? 351 ARG A CA  1 
ATOM   2800 C  C   . ARG A  1 352 ? 48.76998 30.65131  -34.63945 1.000 27.93497 ? 351 ARG A C   1 
ATOM   2801 O  O   . ARG A  1 352 ? 48.00185 29.70743  -34.85854 1.000 29.50354 ? 351 ARG A O   1 
ATOM   2802 C  CB  . ARG A  1 352 ? 49.92602 31.68429  -36.61526 1.000 37.83388 ? 351 ARG A CB  1 
ATOM   2803 C  CG  . ARG A  1 352 ? 49.86482 30.38944  -37.41372 1.000 47.05886 ? 351 ARG A CG  1 
ATOM   2804 C  CD  . ARG A  1 352 ? 51.06050 30.24654  -38.35301 1.000 56.20633 ? 351 ARG A CD  1 
ATOM   2805 N  NE  . ARG A  1 352 ? 52.31676 30.05483  -37.63598 1.000 47.62052 ? 351 ARG A NE  1 
ATOM   2806 C  CZ  . ARG A  1 352 ? 53.19388 31.01699  -37.38166 1.000 52.01239 ? 351 ARG A CZ  1 
ATOM   2807 N  NH1 . ARG A  1 352 ? 52.99154 32.26171  -37.78317 1.000 52.27729 ? 351 ARG A NH1 1 
ATOM   2808 N  NH2 . ARG A  1 352 ? 54.30280 30.72263  -36.70836 1.000 56.75051 ? 351 ARG A NH2 1 
ATOM   2809 N  N   . ILE A  1 353 ? 49.58838 30.66786  -33.59140 1.000 22.62529 ? 352 ILE A N   1 
ATOM   2810 C  CA  . ILE A  1 353 ? 49.61764 29.60904  -32.58980 1.000 26.76159 ? 352 ILE A CA  1 
ATOM   2811 C  C   . ILE A  1 353 ? 48.96092 30.13307  -31.32208 1.000 21.61468 ? 352 ILE A C   1 
ATOM   2812 O  O   . ILE A  1 353 ? 49.20182 31.27432  -30.91189 1.000 24.83894 ? 352 ILE A O   1 
ATOM   2813 C  CB  . ILE A  1 353 ? 51.05376 29.12044  -32.30842 1.000 31.50508 ? 352 ILE A CB  1 
ATOM   2814 C  CG1 . ILE A  1 353 ? 51.58510 28.29765  -33.48378 1.000 31.06615 ? 352 ILE A CG1 1 
ATOM   2815 C  CG2 . ILE A  1 353 ? 51.10883 28.29895  -31.03055 1.000 22.82645 ? 352 ILE A CG2 1 
ATOM   2816 C  CD1 . ILE A  1 353 ? 52.33824 29.10732  -34.50795 1.000 32.31824 ? 352 ILE A CD1 1 
ATOM   2817 N  N   . LEU A  1 354 ? 48.12265 29.29970  -30.70689 1.000 28.62217 ? 353 LEU A N   1 
ATOM   2818 C  CA  . LEU A  1 354 ? 47.38869 29.68219  -29.51181 1.000 28.71970 ? 353 LEU A CA  1 
ATOM   2819 C  C   . LEU A  1 354 ? 47.62663 28.76059  -28.32552 1.000 27.76514 ? 353 LEU A C   1 
ATOM   2820 O  O   . LEU A  1 354 ? 47.00717 28.96705  -27.27587 1.000 38.76767 ? 353 LEU A O   1 
ATOM   2821 C  CB  . LEU A  1 354 ? 45.88258 29.72336  -29.80424 1.000 23.28626 ? 353 LEU A CB  1 
ATOM   2822 C  CG  . LEU A  1 354 ? 45.39644 30.53947  -30.99847 1.000 20.39549 ? 353 LEU A CG  1 
ATOM   2823 C  CD1 . LEU A  1 354 ? 43.96470 30.16087  -31.32824 1.000 15.85609 ? 353 LEU A CD1 1 
ATOM   2824 C  CD2 . LEU A  1 354 ? 45.50237 32.02142  -30.70420 1.000 19.35332 ? 353 LEU A CD2 1 
ATOM   2825 N  N   . ARG A  1 355 ? 48.49105 27.75300  -28.44742 1.000 28.90074 ? 354 ARG A N   1 
ATOM   2826 C  CA  . ARG A  1 355 ? 48.55522 26.74824  -27.39376 1.000 28.39940 ? 354 ARG A CA  1 
ATOM   2827 C  C   . ARG A  1 355 ? 49.87392 25.98399  -27.34672 1.000 35.91361 ? 354 ARG A C   1 
ATOM   2828 O  O   . ARG A  1 355 ? 50.36849 25.67451  -26.25741 1.000 42.80329 ? 354 ARG A O   1 
ATOM   2829 C  CB  . ARG A  1 355 ? 47.39718 25.76393  -27.55853 1.000 28.29525 ? 354 ARG A CB  1 
ATOM   2830 C  CG  . ARG A  1 355 ? 47.21623 24.82308  -26.38851 1.000 35.11367 ? 354 ARG A CG  1 
ATOM   2831 C  CD  . ARG A  1 355 ? 46.09078 23.84334  -26.64804 1.000 28.79700 ? 354 ARG A CD  1 
ATOM   2832 N  NE  . ARG A  1 355 ? 45.77210 23.07047  -25.45509 1.000 33.68657 ? 354 ARG A NE  1 
ATOM   2833 C  CZ  . ARG A  1 355 ? 44.95047 23.48174  -24.49947 1.000 37.88219 ? 354 ARG A CZ  1 
ATOM   2834 N  NH1 . ARG A  1 355 ? 44.34348 24.65639  -24.56813 1.000 24.63948 ? 354 ARG A NH1 1 
ATOM   2835 N  NH2 . ARG A  1 355 ? 44.73209 22.69542  -23.44908 1.000 42.55909 ? 354 ARG A NH2 1 
ATOM   2836 N  N   . LYS A  1 356 ? 50.43686 25.65307  -28.51158 1.000 41.44632 ? 355 LYS A N   1 
ATOM   2837 C  CA  . LYS A  1 356 ? 51.63071 24.81303  -28.60710 1.000 46.92331 ? 355 LYS A CA  1 
ATOM   2838 C  C   . LYS A  1 356 ? 51.38980 23.43331  -28.00191 1.000 45.42511 ? 355 LYS A C   1 
ATOM   2839 O  O   . LYS A  1 356 ? 51.48089 22.41698  -28.69846 1.000 46.55672 ? 355 LYS A O   1 
ATOM   2840 C  CB  . LYS A  1 356 ? 52.83408 25.46628  -27.91580 1.000 44.75635 ? 355 LYS A CB  1 
ATOM   2841 C  CG  . LYS A  1 356 ? 53.02566 26.94450  -28.19816 1.000 45.85682 ? 355 LYS A CG  1 
ATOM   2842 C  CD  . LYS A  1 356 ? 53.93691 27.56680  -27.15131 1.000 52.38650 ? 355 LYS A CD  1 
ATOM   2843 C  CE  . LYS A  1 356 ? 53.40516 27.30881  -25.74613 1.000 52.34681 ? 355 LYS A CE  1 
ATOM   2844 N  NZ  . LYS A  1 356 ? 54.29613 27.86033  -24.68804 1.000 57.70573 ? 355 LYS A NZ  1 
ATOM   2845 N  N   . ARG A  1 357 ? 51.08946 23.39512  -26.70591 1.000 35.74842 ? 356 ARG A N   1 
ATOM   2846 C  CA  . ARG A  1 357 ? 50.94725 22.13385  -25.99452 1.000 44.51562 ? 356 ARG A CA  1 
ATOM   2847 C  C   . ARG A  1 357 ? 49.75676 21.34433  -26.53686 1.000 47.21604 ? 356 ARG A C   1 
ATOM   2848 O  O   . ARG A  1 357 ? 48.70905 21.92451  -26.83851 1.000 45.23442 ? 356 ARG A O   1 
ATOM   2849 C  CB  . ARG A  1 357 ? 50.76796 22.39586  -24.49972 1.000 48.36584 ? 356 ARG A CB  1 
ATOM   2850 C  CG  . ARG A  1 357 ? 51.31790 21.31691  -23.58863 1.000 52.14951 ? 356 ARG A CG  1 
ATOM   2851 C  CD  . ARG A  1 357 ? 51.58186 21.87222  -22.19658 1.000 58.68299 ? 356 ARG A CD  1 
ATOM   2852 N  NE  . ARG A  1 357 ? 52.58474 22.93125  -22.21581 1.000 56.56512 ? 356 ARG A NE  1 
ATOM   2853 C  CZ  . ARG A  1 357 ? 53.89212 22.72531  -22.13170 1.000 52.38398 ? 356 ARG A CZ  1 
ATOM   2854 N  NH1 . ARG A  1 357 ? 54.39373 21.50609  -22.02391 1.000 51.31521 ? 356 ARG A NH1 1 
ATOM   2855 N  NH2 . ARG A  1 357 ? 54.71694 23.76865  -22.15703 1.000 57.99214 ? 356 ARG A NH2 1 
ATOM   2856 N  N   . PRO A  1 358 ? 49.88767 20.02835  -26.68030 1.000 50.96354 ? 357 PRO A N   1 
ATOM   2857 C  CA  . PRO A  1 358 ? 48.76887 19.22017  -27.17839 1.000 41.62194 ? 357 PRO A CA  1 
ATOM   2858 C  C   . PRO A  1 358 ? 47.64562 19.13556  -26.15496 1.000 45.10334 ? 357 PRO A C   1 
ATOM   2859 O  O   . PRO A  1 358 ? 47.76865 19.56032  -25.00442 1.000 44.74703 ? 357 PRO A O   1 
ATOM   2860 C  CB  . PRO A  1 358 ? 49.39934 17.84551  -27.42828 1.000 42.90580 ? 357 PRO A CB  1 
ATOM   2861 C  CG  . PRO A  1 358 ? 50.88163 18.09364  -27.46973 1.000 40.93394 ? 357 PRO A CG  1 
ATOM   2862 C  CD  . PRO A  1 358 ? 51.11929 19.23649  -26.53720 1.000 44.06257 ? 357 PRO A CD  1 
ATOM   2863 N  N   . PHE A  1 359 ? 46.52735 18.56906  -26.59841 1.000 48.30909 ? 358 PHE A N   1 
ATOM   2864 C  CA  . PHE A  1 359 ? 45.36727 18.39201  -25.73137 1.000 42.90345 ? 358 PHE A CA  1 
ATOM   2865 C  C   . PHE A  1 359 ? 45.53259 17.16482  -24.83971 1.000 36.48531 ? 358 PHE A C   1 
ATOM   2866 O  O   . PHE A  1 359 ? 45.61973 16.03768  -25.32749 1.000 37.09375 ? 358 PHE A O   1 
ATOM   2867 C  CB  . PHE A  1 359 ? 44.08461 18.27130  -26.55847 1.000 33.44942 ? 358 PHE A CB  1 
ATOM   2868 C  CG  . PHE A  1 359 ? 43.72464 19.52240  -27.30818 1.000 29.97666 ? 358 PHE A CG  1 
ATOM   2869 C  CD1 . PHE A  1 359 ? 43.51184 20.71215  -26.63288 1.000 24.61531 ? 358 PHE A CD1 1 
ATOM   2870 C  CD2 . PHE A  1 359 ? 43.58284 19.50524  -28.68627 1.000 29.47129 ? 358 PHE A CD2 1 
ATOM   2871 C  CE1 . PHE A  1 359 ? 43.17674 21.86437  -27.31906 1.000 25.24427 ? 358 PHE A CE1 1 
ATOM   2872 C  CE2 . PHE A  1 359 ? 43.24604 20.65434  -29.37758 1.000 20.46004 ? 358 PHE A CE2 1 
ATOM   2873 C  CZ  . PHE A  1 359 ? 43.04382 21.83485  -28.69318 1.000 19.02015 ? 358 PHE A CZ  1 
ATOM   2874 N  N   . HIS A  1 363 ? 45.88068 8.00816   -25.56434 1.000 53.13571 ? 362 HIS A N   1 
ATOM   2875 C  CA  . HIS A  1 363 ? 46.44358 7.19356   -24.49425 1.000 51.59367 ? 362 HIS A CA  1 
ATOM   2876 C  C   . HIS A  1 363 ? 46.08913 5.71952   -24.68754 1.000 55.76802 ? 362 HIS A C   1 
ATOM   2877 O  O   . HIS A  1 363 ? 45.92645 5.25914   -25.81808 1.000 59.29166 ? 362 HIS A O   1 
ATOM   2878 C  CB  . HIS A  1 363 ? 45.96244 7.69852   -23.13267 1.000 52.20004 ? 362 HIS A CB  1 
ATOM   2879 C  CG  . HIS A  1 363 ? 46.40173 9.09672   -22.82322 1.000 67.69636 ? 362 HIS A CG  1 
ATOM   2880 N  ND1 . HIS A  1 363 ? 45.88352 9.82824   -21.77594 1.000 61.28998 ? 362 HIS A ND1 1 
ATOM   2881 C  CD2 . HIS A  1 363 ? 47.31342 9.89706   -23.42560 1.000 63.89992 ? 362 HIS A CD2 1 
ATOM   2882 C  CE1 . HIS A  1 363 ? 46.45552 11.01900  -21.74761 1.000 59.87720 ? 362 HIS A CE1 1 
ATOM   2883 N  NE2 . HIS A  1 363 ? 47.32703 11.08632  -22.73806 1.000 68.12580 ? 362 HIS A NE2 1 
ATOM   2884 N  N   . LYS A  1 364 ? 45.96457 4.97926   -23.58462 1.000 48.27487 ? 363 LYS A N   1 
ATOM   2885 C  CA  . LYS A  1 364 ? 45.84812 3.52925   -23.67934 1.000 53.37152 ? 363 LYS A CA  1 
ATOM   2886 C  C   . LYS A  1 364 ? 44.43706 3.05041   -23.99516 1.000 54.79045 ? 363 LYS A C   1 
ATOM   2887 O  O   . LYS A  1 364 ? 44.29155 1.96042   -24.56097 1.000 57.46653 ? 363 LYS A O   1 
ATOM   2888 C  CB  . LYS A  1 364 ? 46.33069 2.87340   -22.38419 1.000 50.37153 ? 363 LYS A CB  1 
ATOM   2889 C  CG  . LYS A  1 364 ? 47.57785 2.02950   -22.57072 1.000 56.21054 ? 363 LYS A CG  1 
ATOM   2890 C  CD  . LYS A  1 364 ? 47.88567 1.19464   -21.34361 1.000 66.94106 ? 363 LYS A CD  1 
ATOM   2891 C  CE  . LYS A  1 364 ? 49.10973 0.32263   -21.57852 1.000 67.68602 ? 363 LYS A CE  1 
ATOM   2892 N  NZ  . LYS A  1 364 ? 48.94279 -0.56916  -22.76194 1.000 59.75677 ? 363 LYS A NZ  1 
ATOM   2893 N  N   . ILE A  1 365 ? 43.41021 3.83479   -23.65607 1.000 42.66164 ? 364 ILE A N   1 
ATOM   2894 C  CA  . ILE A  1 365 ? 42.00915 3.44584   -23.81241 1.000 36.15998 ? 364 ILE A CA  1 
ATOM   2895 C  C   . ILE A  1 365 ? 41.73209 2.20677   -22.97319 1.000 32.01500 ? 364 ILE A C   1 
ATOM   2896 O  O   . ILE A  1 365 ? 42.08651 1.08611   -23.35622 1.000 33.63070 ? 364 ILE A O   1 
ATOM   2897 C  CB  . ILE A  1 365 ? 41.63353 3.20823   -25.28650 1.000 28.23344 ? 364 ILE A CB  1 
ATOM   2898 C  CG1 . ILE A  1 365 ? 41.45657 4.54188   -26.00087 1.000 22.39067 ? 364 ILE A CG1 1 
ATOM   2899 C  CG2 . ILE A  1 365 ? 40.34700 2.39743   -25.38569 1.000 31.12645 ? 364 ILE A CG2 1 
ATOM   2900 C  CD1 . ILE A  1 365 ? 40.32791 5.36231   -25.42605 1.000 36.55955 ? 364 ILE A CD1 1 
ATOM   2901 N  N   . ASN A  1 366 ? 41.09278 2.40268   -21.82073 1.000 25.50259 ? 365 ASN A N   1 
ATOM   2902 C  CA  . ASN A  1 366 ? 40.81985 1.31651   -20.89153 1.000 32.11149 ? 365 ASN A CA  1 
ATOM   2903 C  C   . ASN A  1 366 ? 39.38943 0.80007   -20.96368 1.000 33.29696 ? 365 ASN A C   1 
ATOM   2904 O  O   . ASN A  1 366 ? 39.13583 -0.33343  -20.53931 1.000 30.80179 ? 365 ASN A O   1 
ATOM   2905 C  CB  . ASN A  1 366 ? 41.11422 1.77003   -19.45492 1.000 37.00783 ? 365 ASN A CB  1 
ATOM   2906 C  CG  . ASN A  1 366 ? 42.52904 2.29293   -19.28676 1.000 41.21224 ? 365 ASN A CG  1 
ATOM   2907 O  OD1 . ASN A  1 366 ? 42.79834 3.47611   -19.50272 1.000 33.52382 ? 365 ASN A OD1 1 
ATOM   2908 N  ND2 . ASN A  1 366 ? 43.44257 1.40991   -18.89997 1.000 46.40145 ? 365 ASN A ND2 1 
ATOM   2909 N  N   . THR A  1 367 ? 38.45589 1.59041   -21.49008 1.000 22.80708 ? 366 THR A N   1 
ATOM   2910 C  CA  . THR A  1 367 ? 37.04498 1.24288   -21.41982 1.000 19.62317 ? 366 THR A CA  1 
ATOM   2911 C  C   . THR A  1 367 ? 36.31345 1.79041   -22.63829 1.000 16.64596 ? 366 THR A C   1 
ATOM   2912 O  O   . THR A  1 367 ? 36.63533 2.87430   -23.13237 1.000 13.10172 ? 366 THR A O   1 
ATOM   2913 C  CB  . THR A  1 367 ? 36.41496 1.78898   -20.13083 1.000 14.16880 ? 366 THR A CB  1 
ATOM   2914 O  OG1 . THR A  1 367 ? 37.18586 1.36223   -19.00057 1.000 23.02406 ? 366 THR A OG1 1 
ATOM   2915 C  CG2 . THR A  1 367 ? 34.98407 1.30136   -19.96990 1.000 16.35063 ? 366 THR A CG2 1 
ATOM   2916 N  N   . LEU A  1 368 ? 35.33607 1.02474   -23.11880 1.000 11.75048 ? 367 LEU A N   1 
ATOM   2917 C  CA  . LEU A  1 368 ? 34.42706 1.44434   -24.17448 1.000 12.76089 ? 367 LEU A CA  1 
ATOM   2918 C  C   . LEU A  1 368 ? 33.00398 1.42812   -23.63645 1.000 11.29711 ? 367 LEU A C   1 
ATOM   2919 O  O   . LEU A  1 368 ? 32.63874 0.54333   -22.85640 1.000 15.77639 ? 367 LEU A O   1 
ATOM   2920 C  CB  . LEU A  1 368 ? 34.52849 0.52726   -25.39624 1.000 16.25335 ? 367 LEU A CB  1 
ATOM   2921 C  CG  . LEU A  1 368 ? 35.90315 0.36303   -26.04346 1.000 17.08690 ? 367 LEU A CG  1 
ATOM   2922 C  CD1 . LEU A  1 368 ? 35.82625 -0.63854  -27.18268 1.000 17.45237 ? 367 LEU A CD1 1 
ATOM   2923 C  CD2 . LEU A  1 368 ? 36.42656 1.70014   -26.53774 1.000 17.99527 ? 367 LEU A CD2 1 
ATOM   2924 N  N   . ARG A  1 369 ? 32.20089 2.40694   -24.04938 1.000 11.75258 ? 368 ARG A N   1 
ATOM   2925 C  CA  . ARG A  1 369 ? 30.82117 2.50516   -23.59043 1.000 11.69325 ? 368 ARG A CA  1 
ATOM   2926 C  C   . ARG A  1 369 ? 29.90738 2.84825   -24.75455 1.000 12.88490 ? 368 ARG A C   1 
ATOM   2927 O  O   . ARG A  1 369 ? 30.21869 3.73596   -25.55359 1.000 13.15587 ? 368 ARG A O   1 
ATOM   2928 C  CB  . ARG A  1 369 ? 30.67059 3.55910   -22.48801 1.000 11.20430 ? 368 ARG A CB  1 
ATOM   2929 C  CG  . ARG A  1 369 ? 31.44406 3.24840   -21.22367 1.000 17.93807 ? 368 ARG A CG  1 
ATOM   2930 C  CD  . ARG A  1 369 ? 31.15026 4.25890   -20.12969 1.000 16.55605 ? 368 ARG A CD  1 
ATOM   2931 N  NE  . ARG A  1 369 ? 32.08476 4.11752   -19.02090 1.000 19.62803 ? 368 ARG A NE  1 
ATOM   2932 C  CZ  . ARG A  1 369 ? 31.93607 3.26088   -18.02033 1.000 19.89579 ? 368 ARG A CZ  1 
ATOM   2933 N  NH1 . ARG A  1 369 ? 30.88020 2.46669   -17.94130 1.000 18.50244 ? 368 ARG A NH1 1 
ATOM   2934 N  NH2 . ARG A  1 369 ? 32.87227 3.19682   -17.07756 1.000 19.34488 ? 368 ARG A NH2 1 
ATOM   2935 N  N   . ASN A  1 370 ? 28.78509 2.14178   -24.84358 1.000 17.67322 ? 369 ASN A N   1 
ATOM   2936 C  CA  . ASN A  1 370 ? 27.71576 2.45682   -25.78100 1.000 17.25600 ? 369 ASN A CA  1 
ATOM   2937 C  C   . ASN A  1 370 ? 26.55246 3.03560   -24.99028 1.000 17.61327 ? 369 ASN A C   1 
ATOM   2938 O  O   . ASN A  1 370 ? 26.07375 2.41022   -24.03799 1.000 21.99096 ? 369 ASN A O   1 
ATOM   2939 C  CB  . ASN A  1 370 ? 27.27633 1.21884   -26.56139 1.000 17.41075 ? 369 ASN A CB  1 
ATOM   2940 C  CG  . ASN A  1 370 ? 28.35101 0.71027   -27.49684 1.000 25.57594 ? 369 ASN A CG  1 
ATOM   2941 O  OD1 . ASN A  1 370 ? 29.29851 1.42851   -27.82052 1.000 24.87013 ? 369 ASN A OD1 1 
ATOM   2942 N  ND2 . ASN A  1 370 ? 28.20690 -0.53322  -27.94436 1.000 24.58316 ? 369 ASN A ND2 1 
ATOM   2943 N  N   . LEU A  1 371 ? 26.11260 4.23133   -25.37203 1.000 15.21661 ? 370 LEU A N   1 
ATOM   2944 C  CA  . LEU A  1 371 ? 25.04548 4.92999   -24.67026 1.000 18.24323 ? 370 LEU A CA  1 
ATOM   2945 C  C   . LEU A  1 371 ? 24.02471 5.41937   -25.68529 1.000 21.22595 ? 370 LEU A C   1 
ATOM   2946 O  O   . LEU A  1 371 ? 24.38470 6.08352   -26.66271 1.000 19.93220 ? 370 LEU A O   1 
ATOM   2947 C  CB  . LEU A  1 371 ? 25.60394 6.09513   -23.84553 1.000 18.64332 ? 370 LEU A CB  1 
ATOM   2948 C  CG  . LEU A  1 371 ? 26.79665 5.70093   -22.96434 1.000 14.38295 ? 370 LEU A CG  1 
ATOM   2949 C  CD1 . LEU A  1 371 ? 28.09542 6.28623   -23.49358 1.000 11.11389 ? 370 LEU A CD1 1 
ATOM   2950 C  CD2 . LEU A  1 371 ? 26.58061 6.08830   -21.51449 1.000 15.32813 ? 370 LEU A CD2 1 
ATOM   2951 N  N   . SER A  1 372 ? 22.75837 5.08609   -25.45460 1.000 18.34976 ? 371 SER A N   1 
ATOM   2952 C  CA  . SER A  1 372 ? 21.68863 5.37516   -26.39715 1.000 16.12735 ? 371 SER A CA  1 
ATOM   2953 C  C   . SER A  1 372 ? 20.89019 6.59127   -25.94997 1.000 18.31760 ? 371 SER A C   1 
ATOM   2954 O  O   . SER A  1 372 ? 20.66521 6.79887   -24.75392 1.000 18.59405 ? 371 SER A O   1 
ATOM   2955 C  CB  . SER A  1 372 ? 20.75159 4.17490   -26.54399 1.000 17.27824 ? 371 SER A CB  1 
ATOM   2956 O  OG  . SER A  1 372 ? 19.99294 3.96877   -25.36489 1.000 21.89111 ? 371 SER A OG  1 
ATOM   2957 N  N   . LEU A  1 373 ? 20.46170 7.38867   -26.92209 1.000 18.06524 ? 372 LEU A N   1 
ATOM   2958 C  CA  . LEU A  1 373 ? 19.55530 8.50551   -26.69732 1.000 15.73256 ? 372 LEU A CA  1 
ATOM   2959 C  C   . LEU A  1 373 ? 18.19227 8.11742   -27.25177 1.000 19.30989 ? 372 LEU A C   1 
ATOM   2960 O  O   . LEU A  1 373 ? 18.05653 7.87604   -28.45608 1.000 23.91760 ? 372 LEU A O   1 
ATOM   2961 C  CB  . LEU A  1 373 ? 20.07145 9.77844   -27.36855 1.000 20.04579 ? 372 LEU A CB  1 
ATOM   2962 C  CG  . LEU A  1 373 ? 21.55764 10.09486  -27.18622 1.000 15.15607 ? 372 LEU A CG  1 
ATOM   2963 C  CD1 . LEU A  1 373 ? 21.93054 11.37514  -27.91146 1.000 11.36112 ? 372 LEU A CD1 1 
ATOM   2964 C  CD2 . LEU A  1 373 ? 21.91526 10.18828  -25.71573 1.000 12.76907 ? 372 LEU A CD2 1 
ATOM   2965 N  N   . GLY A  1 374 ? 17.19292 8.04548   -26.37714 1.000 26.29900 ? 373 GLY A N   1 
ATOM   2966 C  CA  . GLY A  1 374 ? 15.86703 7.63571   -26.79486 1.000 20.47712 ? 373 GLY A CA  1 
ATOM   2967 C  C   . GLY A  1 374 ? 14.75541 8.26218   -25.98128 1.000 22.47811 ? 373 GLY A C   1 
ATOM   2968 O  O   . GLY A  1 374 ? 14.96371 9.27729   -25.30933 1.000 20.86339 ? 373 GLY A O   1 
ATOM   2969 N  N   . ALA A  1 375 ? 13.56789 7.66223   -26.03192 1.000 26.82065 ? 374 ALA A N   1 
ATOM   2970 C  CA  . ALA A  1 375 ? 12.41696 8.19634   -25.32078 1.000 27.01561 ? 374 ALA A CA  1 
ATOM   2971 C  C   . ALA A  1 375 ? 11.39637 7.08866   -25.10957 1.000 24.41807 ? 374 ALA A C   1 
ATOM   2972 O  O   . ALA A  1 375 ? 11.21842 6.22606   -25.97354 1.000 30.31245 ? 374 ALA A O   1 
ATOM   2973 C  CB  . ALA A  1 375 ? 11.78105 9.36458   -26.08412 1.000 24.16246 ? 374 ALA A CB  1 
ATOM   2974 N  N   . SER A  1 376 ? 10.73632 7.12205   -23.95478 1.000 24.76743 ? 375 SER A N   1 
ATOM   2975 C  CA  . SER A  1 376 ? 9.63066  6.22883   -23.64900 1.000 28.38800 ? 375 SER A CA  1 
ATOM   2976 C  C   . SER A  1 376 ? 8.42274  7.05806   -23.23783 1.000 32.06104 ? 375 SER A C   1 
ATOM   2977 O  O   . SER A  1 376 ? 8.53467  8.24796   -22.93455 1.000 30.58958 ? 375 SER A O   1 
ATOM   2978 C  CB  . SER A  1 376 ? 9.98878  5.23238   -22.53674 1.000 21.82178 ? 375 SER A CB  1 
ATOM   2979 O  OG  . SER A  1 376 ? 10.97397 4.31349   -22.97218 1.000 35.82581 ? 375 SER A OG  1 
ATOM   2980 N  N   . LEU A  1 377 ? 7.26048  6.41530   -23.23085 1.000 30.56099 ? 376 LEU A N   1 
ATOM   2981 C  CA  . LEU A  1 377 ? 6.01456  7.06316   -22.85057 1.000 27.08990 ? 376 LEU A CA  1 
ATOM   2982 C  C   . LEU A  1 377 ? 5.63370  6.66889   -21.43077 1.000 29.54689 ? 376 LEU A C   1 
ATOM   2983 O  O   . LEU A  1 377 ? 5.73734  5.49901   -21.05112 1.000 30.38293 ? 376 LEU A O   1 
ATOM   2984 C  CB  . LEU A  1 377 ? 4.88827  6.69029   -23.81575 1.000 25.36939 ? 376 LEU A CB  1 
ATOM   2985 C  CG  . LEU A  1 377 ? 5.05111  7.17544   -25.25667 1.000 25.74196 ? 376 LEU A CG  1 
ATOM   2986 C  CD1 . LEU A  1 377 ? 3.94211  6.62432   -26.13676 1.000 17.70692 ? 376 LEU A CD1 1 
ATOM   2987 C  CD2 . LEU A  1 377 ? 5.07511  8.69631   -25.31058 1.000 26.04832 ? 376 LEU A CD2 1 
ATOM   2988 N  N   . ASP A  1 378 ? 5.19832  7.65192   -20.64839 1.000 29.84675 ? 377 ASP A N   1 
ATOM   2989 C  CA  . ASP A  1 378 ? 4.73428  7.40118   -19.29354 1.000 32.66832 ? 377 ASP A CA  1 
ATOM   2990 C  C   . ASP A  1 378 ? 3.23388  7.10617   -19.32019 1.000 35.86152 ? 377 ASP A C   1 
ATOM   2991 O  O   . ASP A  1 378 ? 2.62158  6.97862   -20.38387 1.000 36.70371 ? 377 ASP A O   1 
ATOM   2992 C  CB  . ASP A  1 378 ? 5.08270  8.57924   -18.38308 1.000 30.06655 ? 377 ASP A CB  1 
ATOM   2993 C  CG  . ASP A  1 378 ? 4.49293  9.89370   -18.86599 1.000 33.37804 ? 377 ASP A CG  1 
ATOM   2994 O  OD1 . ASP A  1 378 ? 3.83656  9.90889   -19.92785 1.000 34.65898 ? 377 ASP A OD1 1 
ATOM   2995 O  OD2 . ASP A  1 378 ? 4.68893  10.91806  -18.17911 1.000 35.45466 ? 377 ASP A OD2 1 
ATOM   2996 N  N   . GLN A  1 379 ? 2.62165  7.00111   -18.13947 1.000 36.57329 ? 378 GLN A N   1 
ATOM   2997 C  CA  . GLN A  1 379 ? 1.21130  6.64016   -18.06125 1.000 38.07682 ? 378 GLN A CA  1 
ATOM   2998 C  C   . GLN A  1 379 ? 0.30045  7.71314   -18.64188 1.000 41.19647 ? 378 GLN A C   1 
ATOM   2999 O  O   . GLN A  1 379 ? -0.81422 7.39492   -19.07008 1.000 40.67049 ? 378 GLN A O   1 
ATOM   3000 C  CB  . GLN A  1 379 ? 0.82591  6.35578   -16.60975 1.000 36.45529 ? 378 GLN A CB  1 
ATOM   3001 C  CG  . GLN A  1 379 ? 0.95097  7.56093   -15.69172 1.000 38.25046 ? 378 GLN A CG  1 
ATOM   3002 C  CD  . GLN A  1 379 ? 0.85010  7.19164   -14.22677 1.000 38.74283 ? 378 GLN A CD  1 
ATOM   3003 O  OE1 . GLN A  1 379 ? -0.15059 7.47670   -13.57017 1.000 47.33118 ? 378 GLN A OE1 1 
ATOM   3004 N  NE2 . GLN A  1 379 ? 1.89293  6.55803   -13.70396 1.000 37.40228 ? 378 GLN A NE2 1 
ATOM   3005 N  N   . TYR A  1 380 ? 0.74710  8.96501   -18.67712 1.000 34.86108 ? 379 TYR A N   1 
ATOM   3006 C  CA  . TYR A  1 380 ? -0.05055 10.05187  -19.22302 1.000 36.63393 ? 379 TYR A CA  1 
ATOM   3007 C  C   . TYR A  1 380 ? 0.17176  10.25715  -20.71430 1.000 33.65423 ? 379 TYR A C   1 
ATOM   3008 O  O   . TYR A  1 380 ? -0.41486 11.17887  -21.29022 1.000 27.74271 ? 379 TYR A O   1 
ATOM   3009 C  CB  . TYR A  1 380 ? 0.25406  11.35454  -18.47902 1.000 36.97236 ? 379 TYR A CB  1 
ATOM   3010 C  CG  . TYR A  1 380 ? 0.20721  11.23268  -16.97415 1.000 36.09823 ? 379 TYR A CG  1 
ATOM   3011 C  CD1 . TYR A  1 380 ? -1.00526 11.18944  -16.29861 1.000 35.58263 ? 379 TYR A CD1 1 
ATOM   3012 C  CD2 . TYR A  1 380 ? 1.37666  11.17204  -16.22756 1.000 33.89401 ? 379 TYR A CD2 1 
ATOM   3013 C  CE1 . TYR A  1 380 ? -1.05158 11.08326  -14.92218 1.000 35.04296 ? 379 TYR A CE1 1 
ATOM   3014 C  CE2 . TYR A  1 380 ? 1.34026  11.06617  -14.85116 1.000 34.71718 ? 379 TYR A CE2 1 
ATOM   3015 C  CZ  . TYR A  1 380 ? 0.12401  11.02183  -14.20380 1.000 36.93373 ? 379 TYR A CZ  1 
ATOM   3016 O  OH  . TYR A  1 380 ? 0.08463  10.91585  -12.83264 1.000 37.93892 ? 379 TYR A OH  1 
ATOM   3017 N  N   . GLY A  1 381 ? 0.99811  9.42931   -21.34999 1.000 33.46463 ? 380 GLY A N   1 
ATOM   3018 C  CA  . GLY A  1 381 ? 1.30418  9.60139   -22.75453 1.000 30.79572 ? 380 GLY A CA  1 
ATOM   3019 C  C   . GLY A  1 381 ? 2.39518  10.60279  -23.05481 1.000 29.77739 ? 380 GLY A C   1 
ATOM   3020 O  O   . GLY A  1 381 ? 2.60998  10.92734  -24.22901 1.000 26.32408 ? 380 GLY A O   1 
ATOM   3021 N  N   . ARG A  1 382 ? 3.09199  11.10514  -22.03414 1.000 26.08756 ? 381 ARG A N   1 
ATOM   3022 C  CA  . ARG A  1 382 ? 4.15642  12.07442  -22.25363 1.000 27.68399 ? 381 ARG A CA  1 
ATOM   3023 C  C   . ARG A  1 382 ? 5.45555  11.35929  -22.61908 1.000 29.66258 ? 381 ARG A C   1 
ATOM   3024 O  O   . ARG A  1 382 ? 5.74232  10.28165  -22.09029 1.000 27.27465 ? 381 ARG A O   1 
ATOM   3025 C  CB  . ARG A  1 382 ? 4.37664  12.92559  -21.00579 1.000 27.08727 ? 381 ARG A CB  1 
ATOM   3026 C  CG  . ARG A  1 382 ? 3.15666  13.70122  -20.55410 1.000 25.57803 ? 381 ARG A CG  1 
ATOM   3027 C  CD  . ARG A  1 382 ? 3.46726  14.53858  -19.32448 1.000 31.25476 ? 381 ARG A CD  1 
ATOM   3028 N  NE  . ARG A  1 382 ? 3.79039  13.71953  -18.16239 1.000 26.54715 ? 381 ARG A NE  1 
ATOM   3029 C  CZ  . ARG A  1 382 ? 3.99905  14.19989  -16.94423 1.000 23.98539 ? 381 ARG A CZ  1 
ATOM   3030 N  NH1 . ARG A  1 382 ? 3.93181  15.49683  -16.69196 1.000 26.34006 ? 381 ARG A NH1 1 
ATOM   3031 N  NH2 . ARG A  1 382 ? 4.28028  13.35787  -15.95391 1.000 26.61870 ? 381 ARG A NH2 1 
ATOM   3032 N  N   . PRO A  1 383 ? 6.25553  11.93284  -23.51649 1.000 26.20785 ? 382 PRO A N   1 
ATOM   3033 C  CA  . PRO A  1 383 ? 7.55706  11.33030  -23.83037 1.000 24.45201 ? 382 PRO A CA  1 
ATOM   3034 C  C   . PRO A  1 383 ? 8.53948  11.53436  -22.68613 1.000 20.42463 ? 382 PRO A C   1 
ATOM   3035 O  O   . PRO A  1 383 ? 8.70980  12.64752  -22.18414 1.000 25.65244 ? 382 PRO A O   1 
ATOM   3036 C  CB  . PRO A  1 383 ? 7.99731  12.07473  -25.09539 1.000 22.79857 ? 382 PRO A CB  1 
ATOM   3037 C  CG  . PRO A  1 383 ? 7.30197  13.38717  -25.00990 1.000 22.80192 ? 382 PRO A CG  1 
ATOM   3038 C  CD  . PRO A  1 383 ? 5.97888  13.11868  -24.34471 1.000 26.58916 ? 382 PRO A CD  1 
ATOM   3039 N  N   . VAL A  1 384 ? 9.17819  10.44596  -22.27329 1.000 22.71468 ? 383 VAL A N   1 
ATOM   3040 C  CA  . VAL A  1 384 ? 10.19467 10.46084  -21.22873 1.000 21.18852 ? 383 VAL A CA  1 
ATOM   3041 C  C   . VAL A  1 384 ? 11.53149 10.22958  -21.91971 1.000 25.08312 ? 383 VAL A C   1 
ATOM   3042 O  O   . VAL A  1 384 ? 11.87535 9.09347   -22.26370 1.000 25.41867 ? 383 VAL A O   1 
ATOM   3043 C  CB  . VAL A  1 384 ? 9.93142  9.40039   -20.15362 1.000 19.83570 ? 383 VAL A CB  1 
ATOM   3044 C  CG1 . VAL A  1 384 ? 10.94859 9.51896   -19.02878 1.000 19.41213 ? 383 VAL A CG1 1 
ATOM   3045 C  CG2 . VAL A  1 384 ? 8.51394  9.51999   -19.62175 1.000 25.00075 ? 383 VAL A CG2 1 
ATOM   3046 N  N   . LEU A  1 385 ? 12.28927 11.30109  -22.13519 1.000 23.70780 ? 384 LEU A N   1 
ATOM   3047 C  CA  . LEU A  1 385 ? 13.59152 11.16616  -22.77263 1.000 21.35527 ? 384 LEU A CA  1 
ATOM   3048 C  C   . LEU A  1 385 ? 14.58410 10.55128  -21.79556 1.000 18.07500 ? 384 LEU A C   1 
ATOM   3049 O  O   . LEU A  1 385 ? 14.64306 10.94071  -20.62545 1.000 15.75254 ? 384 LEU A O   1 
ATOM   3050 C  CB  . LEU A  1 385 ? 14.08344 12.52149  -23.27269 1.000 21.34162 ? 384 LEU A CB  1 
ATOM   3051 C  CG  . LEU A  1 385 ? 13.24804 13.06246  -24.43618 1.000 22.71785 ? 384 LEU A CG  1 
ATOM   3052 C  CD1 . LEU A  1 385 ? 12.18838 14.04371  -23.94911 1.000 22.84329 ? 384 LEU A CD1 1 
ATOM   3053 C  CD2 . LEU A  1 385 ? 14.13259 13.68430  -25.50444 1.000 25.52146 ? 384 LEU A CD2 1 
ATOM   3054 N  N   . LEU A  1 386 ? 15.35809 9.57934   -22.27523 1.000 21.95108 ? 385 LEU A N   1 
ATOM   3055 C  CA  . LEU A  1 386 ? 16.16018 8.73920   -21.40046 1.000 21.74410 ? 385 LEU A CA  1 
ATOM   3056 C  C   . LEU A  1 386 ? 17.54498 8.51957   -21.98861 1.000 16.34332 ? 385 LEU A C   1 
ATOM   3057 O  O   . LEU A  1 386 ? 17.73923 8.56288   -23.20616 1.000 15.99819 ? 385 LEU A O   1 
ATOM   3058 C  CB  . LEU A  1 386 ? 15.48596 7.38023   -21.16632 1.000 21.49763 ? 385 LEU A CB  1 
ATOM   3059 C  CG  . LEU A  1 386 ? 14.12897 7.39465   -20.46359 1.000 18.18656 ? 385 LEU A CG  1 
ATOM   3060 C  CD1 . LEU A  1 386 ? 13.47294 6.02534   -20.54123 1.000 21.21908 ? 385 LEU A CD1 1 
ATOM   3061 C  CD2 . LEU A  1 386 ? 14.29092 7.83403   -19.01869 1.000 18.08984 ? 385 LEU A CD2 1 
ATOM   3062 N  N   . LEU A  1 387 ? 18.50414 8.28029   -21.09862 1.000 19.61380 ? 386 LEU A N   1 
ATOM   3063 C  CA  . LEU A  1 387 ? 19.84234 7.83413   -21.46250 1.000 16.57025 ? 386 LEU A CA  1 
ATOM   3064 C  C   . LEU A  1 387 ? 19.92606 6.33652   -21.19889 1.000 20.54413 ? 386 LEU A C   1 
ATOM   3065 O  O   . LEU A  1 387 ? 19.70932 5.89221   -20.06536 1.000 17.24380 ? 386 LEU A O   1 
ATOM   3066 C  CB  . LEU A  1 387 ? 20.90803 8.58054   -20.66056 1.000 13.81558 ? 386 LEU A CB  1 
ATOM   3067 C  CG  . LEU A  1 387 ? 20.94165 10.10111  -20.80923 1.000 15.42863 ? 386 LEU A CG  1 
ATOM   3068 C  CD1 . LEU A  1 387 ? 21.87041 10.72503  -19.77952 1.000 13.95334 ? 386 LEU A CD1 1 
ATOM   3069 C  CD2 . LEU A  1 387 ? 21.37247 10.47486  -22.21194 1.000 15.66670 ? 386 LEU A CD2 1 
ATOM   3070 N  N   . ASN A  1 388 ? 20.22771 5.56394   -22.24448 1.000 23.89525 ? 387 ASN A N   1 
ATOM   3071 C  CA  . ASN A  1 388 ? 20.27203 4.10329   -22.16134 1.000 16.25496 ? 387 ASN A CA  1 
ATOM   3072 C  C   . ASN A  1 388 ? 18.95589 3.52264   -21.65127 1.000 19.40217 ? 387 ASN A C   1 
ATOM   3073 O  O   . ASN A  1 388 ? 18.95074 2.51902   -20.93392 1.000 18.84701 ? 387 ASN A O   1 
ATOM   3074 C  CB  . ASN A  1 388 ? 21.43587 3.62757   -21.28646 1.000 18.61218 ? 387 ASN A CB  1 
ATOM   3075 C  CG  . ASN A  1 388 ? 22.73994 3.54172   -22.04888 1.000 24.04251 ? 387 ASN A CG  1 
ATOM   3076 O  OD1 . ASN A  1 388 ? 22.76301 3.16103   -23.22042 1.000 30.37356 ? 387 ASN A OD1 1 
ATOM   3077 N  ND2 . ASN A  1 388 ? 23.83644 3.89317   -21.38773 1.000 21.33997 ? 387 ASN A ND2 1 
ATOM   3078 N  N   . ASN A  1 389 ? 17.83573 4.15705   -22.01277 1.000 19.52667 ? 388 ASN A N   1 
ATOM   3079 C  CA  . ASN A  1 389 ? 16.49988 3.69943   -21.62007 1.000 20.24614 ? 388 ASN A CA  1 
ATOM   3080 C  C   . ASN A  1 389 ? 16.40812 3.48158   -20.11059 1.000 21.60288 ? 388 ASN A C   1 
ATOM   3081 O  O   . ASN A  1 389 ? 15.71553 2.57950   -19.63474 1.000 23.51880 ? 388 ASN A O   1 
ATOM   3082 C  CB  . ASN A  1 389 ? 16.11487 2.42586   -22.37895 1.000 26.15975 ? 388 ASN A CB  1 
ATOM   3083 C  CG  . ASN A  1 389 ? 14.62165 2.16123   -22.36157 1.000 27.26611 ? 388 ASN A CG  1 
ATOM   3084 O  OD1 . ASN A  1 389 ? 13.81286 3.08758   -22.42214 1.000 25.69459 ? 388 ASN A OD1 1 
ATOM   3085 N  ND2 . ASN A  1 389 ? 14.24913 0.89028   -22.27257 1.000 19.77956 ? 388 ASN A ND2 1 
ATOM   3086 N  N   . THR A  1 390 ? 17.11084 4.31442   -19.34737 1.000 20.94931 ? 389 THR A N   1 
ATOM   3087 C  CA  . THR A  1 390 ? 17.29197 4.11451   -17.91715 1.000 18.03473 ? 389 THR A CA  1 
ATOM   3088 C  C   . THR A  1 390 ? 16.94428 5.40085   -17.18396 1.000 19.14731 ? 389 THR A C   1 
ATOM   3089 O  O   . THR A  1 390 ? 17.45428 6.47087   -17.53052 1.000 22.16516 ? 389 THR A O   1 
ATOM   3090 C  CB  . THR A  1 390 ? 18.73523 3.69156   -17.61491 1.000 19.09223 ? 389 THR A CB  1 
ATOM   3091 O  OG1 . THR A  1 390 ? 19.03782 2.48389   -18.32408 1.000 17.72149 ? 389 THR A OG1 1 
ATOM   3092 C  CG2 . THR A  1 390 ? 18.93066 3.45492   -16.13872 1.000 16.46103 ? 389 THR A CG2 1 
ATOM   3093 N  N   . LYS A  1 391 ? 16.07570 5.29881   -16.17953 1.000 26.56576 ? 390 LYS A N   1 
ATOM   3094 C  CA  . LYS A  1 391 ? 15.65212 6.48232   -15.44729 1.000 26.54480 ? 390 LYS A CA  1 
ATOM   3095 C  C   . LYS A  1 391 ? 16.75436 6.95783   -14.50264 1.000 25.02002 ? 390 LYS A C   1 
ATOM   3096 O  O   . LYS A  1 391 ? 17.75387 6.27362   -14.26129 1.000 27.32700 ? 390 LYS A O   1 
ATOM   3097 C  CB  . LYS A  1 391 ? 14.36971 6.21102   -14.65765 1.000 25.68425 ? 390 LYS A CB  1 
ATOM   3098 C  CG  . LYS A  1 391 ? 13.08790 6.30656   -15.47315 1.000 29.44833 ? 390 LYS A CG  1 
ATOM   3099 C  CD  . LYS A  1 391 ? 11.92459 6.82923   -14.63247 1.000 49.07958 ? 390 LYS A CD  1 
ATOM   3100 C  CE  . LYS A  1 391 ? 11.81556 8.34930   -14.72722 1.000 42.76013 ? 390 LYS A CE  1 
ATOM   3101 N  NZ  . LYS A  1 391 ? 10.66562 8.91403   -13.96320 1.000 42.31417 ? 390 LYS A NZ  1 
ATOM   3102 N  N   . TRP A  1 392 ? 16.55084 8.16029   -13.96189 1.000 23.67567 ? 391 TRP A N   1 
ATOM   3103 C  CA  . TRP A  1 392 ? 17.51251 8.74202   -13.03297 1.000 18.44709 ? 391 TRP A CA  1 
ATOM   3104 C  C   . TRP A  1 392 ? 17.54437 7.99307   -11.70620 1.000 28.72176 ? 391 TRP A C   1 
ATOM   3105 O  O   . TRP A  1 392 ? 18.60822 7.88323   -11.08584 1.000 27.93265 ? 391 TRP A O   1 
ATOM   3106 C  CB  . TRP A  1 392 ? 17.17954 10.21805  -12.81771 1.000 19.37664 ? 391 TRP A CB  1 
ATOM   3107 C  CG  . TRP A  1 392 ? 17.76735 10.82411  -11.58393 1.000 21.22622 ? 391 TRP A CG  1 
ATOM   3108 C  CD1 . TRP A  1 392 ? 17.14158 11.00976  -10.38708 1.000 23.58014 ? 391 TRP A CD1 1 
ATOM   3109 C  CD2 . TRP A  1 392 ? 19.09365 11.34342  -11.42824 1.000 17.48820 ? 391 TRP A CD2 1 
ATOM   3110 N  NE1 . TRP A  1 392 ? 17.99716 11.60708  -9.49253  1.000 22.13046 ? 391 TRP A NE1 1 
ATOM   3111 C  CE2 . TRP A  1 392 ? 19.20196 11.82226  -10.10767 1.000 15.90609 ? 391 TRP A CE2 1 
ATOM   3112 C  CE3 . TRP A  1 392 ? 20.19997 11.44735  -12.27603 1.000 17.30965 ? 391 TRP A CE3 1 
ATOM   3113 C  CZ2 . TRP A  1 392 ? 20.37084 12.39427  -9.61504  1.000 14.97178 ? 391 TRP A CZ2 1 
ATOM   3114 C  CZ3 . TRP A  1 392 ? 21.36001 12.01565  -11.78462 1.000 18.69598 ? 391 TRP A CZ3 1 
ATOM   3115 C  CH2 . TRP A  1 392 ? 21.43647 12.48163  -10.46633 1.000 15.95735 ? 391 TRP A CH2 1 
ATOM   3116 N  N   . HIS A  1 393 ? 16.39848 7.46758   -11.26122 1.000 38.04227 ? 392 HIS A N   1 
ATOM   3117 C  CA  . HIS A  1 393 ? 16.33800 6.73894   -9.99773  1.000 32.33599 ? 392 HIS A CA  1 
ATOM   3118 C  C   . HIS A  1 393 ? 17.18451 5.47189   -10.01685 1.000 30.53859 ? 392 HIS A C   1 
ATOM   3119 O  O   . HIS A  1 393 ? 17.60112 5.00168   -8.95360  1.000 24.25807 ? 392 HIS A O   1 
ATOM   3120 C  CB  . HIS A  1 393 ? 14.88983 6.35845   -9.66410  1.000 44.82489 ? 392 HIS A CB  1 
ATOM   3121 C  CG  . HIS A  1 393 ? 13.90831 7.48441   -9.79135  1.000 62.12215 ? 392 HIS A CG  1 
ATOM   3122 N  ND1 . HIS A  1 393 ? 13.60196 8.07692   -10.99831 1.000 50.22815 ? 392 HIS A ND1 1 
ATOM   3123 C  CD2 . HIS A  1 393 ? 13.14183 8.10600   -8.86324  1.000 54.27353 ? 392 HIS A CD2 1 
ATOM   3124 C  CE1 . HIS A  1 393 ? 12.70195 9.02483   -10.80569 1.000 52.77126 ? 392 HIS A CE1 1 
ATOM   3125 N  NE2 . HIS A  1 393 ? 12.40532 9.06261   -9.51899  1.000 47.21889 ? 392 HIS A NE2 1 
ATOM   3126 N  N   . GLU A  1 394 ? 17.44443 4.91324   -11.19669 1.000 29.65093 ? 393 GLU A N   1 
ATOM   3127 C  CA  . GLU A  1 394 ? 18.06929 3.60651   -11.31140 1.000 26.30484 ? 393 GLU A CA  1 
ATOM   3128 C  C   . GLU A  1 394 ? 19.51622 3.63954   -10.81628 1.000 22.86496 ? 393 GLU A C   1 
ATOM   3129 O  O   . GLU A  1 394 ? 20.13240 4.70488   -10.73588 1.000 27.59307 ? 393 GLU A O   1 
ATOM   3130 C  CB  . GLU A  1 394 ? 18.01925 3.13869   -12.76306 1.000 28.18475 ? 393 GLU A CB  1 
ATOM   3131 C  CG  . GLU A  1 394 ? 16.66121 3.31195   -13.42549 1.000 31.91929 ? 393 GLU A CG  1 
ATOM   3132 C  CD  . GLU A  1 394 ? 15.71300 2.16797   -13.13657 1.000 37.97543 ? 393 GLU A CD  1 
ATOM   3133 O  OE1 . GLU A  1 394 ? 16.17494 1.12239   -12.63362 1.000 38.85104 ? 393 GLU A OE1 1 
ATOM   3134 O  OE2 . GLU A  1 394 ? 14.50417 2.31510   -13.41583 1.000 38.28472 ? 393 GLU A OE2 1 
ATOM   3135 N  N   . PRO A  1 395 ? 20.07613 2.47786   -10.47060 1.000 21.04285 ? 394 PRO A N   1 
ATOM   3136 C  CA  . PRO A  1 395 ? 21.46935 2.43318   -10.00957 1.000 19.44330 ? 394 PRO A CA  1 
ATOM   3137 C  C   . PRO A  1 395 ? 22.43748 2.95028   -11.06342 1.000 18.49707 ? 394 PRO A C   1 
ATOM   3138 O  O   . PRO A  1 395 ? 22.14418 2.98150   -12.26040 1.000 21.77418 ? 394 PRO A O   1 
ATOM   3139 C  CB  . PRO A  1 395 ? 21.70278 0.94464   -9.72763  1.000 12.92033 ? 394 PRO A CB  1 
ATOM   3140 C  CG  . PRO A  1 395 ? 20.34559 0.40187   -9.46232  1.000 19.40831 ? 394 PRO A CG  1 
ATOM   3141 C  CD  . PRO A  1 395 ? 19.41224 1.16842   -10.34111 1.000 23.29087 ? 394 PRO A CD  1 
ATOM   3142 N  N   . VAL A  1 396 ? 23.61851 3.35633   -10.59399 1.000 13.36565 ? 395 VAL A N   1 
ATOM   3143 C  CA  . VAL A  1 396 ? 24.60710 3.96117   -11.47621 1.000 14.97116 ? 395 VAL A CA  1 
ATOM   3144 C  C   . VAL A  1 396 ? 25.25554 2.88553   -12.33735 1.000 18.82760 ? 395 VAL A C   1 
ATOM   3145 O  O   . VAL A  1 396 ? 25.51934 1.76500   -11.87942 1.000 24.11346 ? 395 VAL A O   1 
ATOM   3146 C  CB  . VAL A  1 396 ? 25.65175 4.74361   -10.65866 1.000 14.32068 ? 395 VAL A CB  1 
ATOM   3147 C  CG1 . VAL A  1 396 ? 26.46574 3.81221   -9.76971  1.000 17.87787 ? 395 VAL A CG1 1 
ATOM   3148 C  CG2 . VAL A  1 396 ? 26.55878 5.55073   -11.57486 1.000 15.71394 ? 395 VAL A CG2 1 
ATOM   3149 N  N   . THR A  1 397 ? 25.49387 3.21674   -13.60404 1.000 21.56938 ? 396 THR A N   1 
ATOM   3150 C  CA  . THR A  1 397 ? 26.13087 2.31063   -14.54869 1.000 19.59309 ? 396 THR A CA  1 
ATOM   3151 C  C   . THR A  1 397 ? 27.38634 2.88102   -15.18467 1.000 19.16042 ? 396 THR A C   1 
ATOM   3152 O  O   . THR A  1 397 ? 28.28816 2.11363   -15.52771 1.000 27.96786 ? 396 THR A O   1 
ATOM   3153 C  CB  . THR A  1 397 ? 25.15199 1.91951   -15.66772 1.000 18.78529 ? 396 THR A CB  1 
ATOM   3154 O  OG1 . THR A  1 397 ? 24.74578 3.09472   -16.37982 1.000 23.13130 ? 396 THR A OG1 1 
ATOM   3155 C  CG2 . THR A  1 397 ? 23.92490 1.23029   -15.08913 1.000 11.63944 ? 396 THR A CG2 1 
ATOM   3156 N  N   . GLU A  1 398 ? 27.46768 4.19756   -15.35776 1.000 17.78341 ? 397 GLU A N   1 
ATOM   3157 C  CA  . GLU A  1 398 ? 28.66383 4.84048   -15.89647 1.000 17.86089 ? 397 GLU A CA  1 
ATOM   3158 C  C   . GLU A  1 398 ? 29.64890 5.01613   -14.74932 1.000 18.31848 ? 397 GLU A C   1 
ATOM   3159 O  O   . GLU A  1 398 ? 29.64030 6.02079   -14.03601 1.000 19.26473 ? 397 GLU A O   1 
ATOM   3160 C  CB  . GLU A  1 398 ? 28.31683 6.16913   -16.55692 1.000 12.94861 ? 397 GLU A CB  1 
ATOM   3161 C  CG  . GLU A  1 398 ? 27.67675 6.03784   -17.93532 1.000 13.20112 ? 397 GLU A CG  1 
ATOM   3162 C  CD  . GLU A  1 398 ? 26.30676 5.38365   -17.89347 1.000 17.05602 ? 397 GLU A CD  1 
ATOM   3163 O  OE1 . GLU A  1 398 ? 25.34636 6.03544   -17.43159 1.000 15.35645 ? 397 GLU A OE1 1 
ATOM   3164 O  OE2 . GLU A  1 398 ? 26.19374 4.21165   -18.31180 1.000 13.71154 ? 397 GLU A OE2 1 
ATOM   3165 N  N   . THR A  1 399 ? 30.51521 4.01592   -14.56817 1.000 17.61502 ? 398 THR A N   1 
ATOM   3166 C  CA  . THR A  1 399 ? 31.46337 3.96749   -13.45644 1.000 18.30294 ? 398 THR A CA  1 
ATOM   3167 C  C   . THR A  1 399 ? 32.88588 3.86508   -13.99967 1.000 15.67476 ? 398 THR A C   1 
ATOM   3168 O  O   . THR A  1 399 ? 33.49600 2.78723   -13.96470 1.000 18.43564 ? 398 THR A O   1 
ATOM   3169 C  CB  . THR A  1 399 ? 31.16053 2.79827   -12.51942 1.000 15.75024 ? 398 THR A CB  1 
ATOM   3170 O  OG1 . THR A  1 399 ? 31.06797 1.58874   -13.28219 1.000 18.47191 ? 398 THR A OG1 1 
ATOM   3171 C  CG2 . THR A  1 399 ? 29.85072 3.02819   -11.78677 1.000 18.33690 ? 398 THR A CG2 1 
ATOM   3172 N  N   . PRO A  1 400 ? 33.44903 4.95864   -14.50425 1.000 15.71281 ? 399 PRO A N   1 
ATOM   3173 C  CA  . PRO A  1 400 ? 34.85881 4.94240   -14.90029 1.000 14.45902 ? 399 PRO A CA  1 
ATOM   3174 C  C   . PRO A  1 400 ? 35.78038 5.02142   -13.69498 1.000 18.68644 ? 399 PRO A C   1 
ATOM   3175 O  O   . PRO A  1 400 ? 35.42909 5.55454   -12.64010 1.000 18.89358 ? 399 PRO A O   1 
ATOM   3176 C  CB  . PRO A  1 400 ? 34.99439 6.19466   -15.77448 1.000 17.50039 ? 399 PRO A CB  1 
ATOM   3177 C  CG  . PRO A  1 400 ? 33.94885 7.11495   -15.25832 1.000 16.54139 ? 399 PRO A CG  1 
ATOM   3178 C  CD  . PRO A  1 400 ? 32.80047 6.24101   -14.82341 1.000 21.31482 ? 399 PRO A CD  1 
ATOM   3179 N  N   . ALA A  1 401 ? 36.97862 4.47498   -13.86660 1.000 21.89131 ? 400 ALA A N   1 
ATOM   3180 C  CA  . ALA A  1 401 ? 37.98316 4.49247   -12.81642 1.000 17.24750 ? 400 ALA A CA  1 
ATOM   3181 C  C   . ALA A  1 401 ? 38.79306 5.78095   -12.87874 1.000 17.46577 ? 400 ALA A C   1 
ATOM   3182 O  O   . ALA A  1 401 ? 38.99438 6.36030   -13.94923 1.000 14.60901 ? 400 ALA A O   1 
ATOM   3183 C  CB  . ALA A  1 401 ? 38.91175 3.28269   -12.93102 1.000 14.42238 ? 400 ALA A CB  1 
ATOM   3184 N  N   . LEU A  1 402 ? 39.25180 6.22920   -11.70955 1.000 19.27679 ? 401 LEU A N   1 
ATOM   3185 C  CA  . LEU A  1 402 ? 40.03233 7.45652   -11.60653 1.000 17.69781 ? 401 LEU A CA  1 
ATOM   3186 C  C   . LEU A  1 402 ? 41.29701 7.36557   -12.45068 1.000 17.12325 ? 401 LEU A C   1 
ATOM   3187 O  O   . LEU A  1 402 ? 42.18394 6.55328   -12.16972 1.000 17.86136 ? 401 LEU A O   1 
ATOM   3188 C  CB  . LEU A  1 402 ? 40.38437 7.74447   -10.14537 1.000 22.55513 ? 401 LEU A CB  1 
ATOM   3189 C  CG  . LEU A  1 402 ? 41.20583 9.00611   -9.86807  1.000 20.71486 ? 401 LEU A CG  1 
ATOM   3190 C  CD1 . LEU A  1 402 ? 40.42576 10.25811  -10.24465 1.000 14.39535 ? 401 LEU A CD1 1 
ATOM   3191 C  CD2 . LEU A  1 402 ? 41.63443 9.05458   -8.41069  1.000 17.73773 ? 401 LEU A CD2 1 
ATOM   3192 N  N   . GLY A  1 403 ? 41.38493 8.19340   -13.48847 1.000 17.50144 ? 402 GLY A N   1 
ATOM   3193 C  CA  . GLY A  1 403 ? 42.50982 8.17491   -14.39759 1.000 15.61093 ? 402 GLY A CA  1 
ATOM   3194 C  C   . GLY A  1 403 ? 42.29354 7.38178   -15.66652 1.000 14.42023 ? 402 GLY A C   1 
ATOM   3195 O  O   . GLY A  1 403 ? 43.18754 7.35982   -16.52036 1.000 16.57714 ? 402 GLY A O   1 
ATOM   3196 N  N   . SER A  1 404 ? 41.14163 6.73437   -15.82002 1.000 18.32841 ? 403 SER A N   1 
ATOM   3197 C  CA  . SER A  1 404 ? 40.86574 5.94749   -17.01240 1.000 17.75607 ? 403 SER A CA  1 
ATOM   3198 C  C   . SER A  1 404 ? 40.54165 6.84955   -18.19410 1.000 18.72740 ? 403 SER A C   1 
ATOM   3199 O  O   . SER A  1 404 ? 39.89344 7.88934   -18.04560 1.000 16.76447 ? 403 SER A O   1 
ATOM   3200 C  CB  . SER A  1 404 ? 39.70175 4.98653   -16.76714 1.000 16.64726 ? 403 SER A CB  1 
ATOM   3201 O  OG  . SER A  1 404 ? 40.05922 3.97142   -15.84692 1.000 26.17102 ? 403 SER A OG  1 
ATOM   3202 N  N   . THR A  1 405 ? 41.00169 6.44247   -19.37177 1.000 19.87645 ? 404 THR A N   1 
ATOM   3203 C  CA  . THR A  1 405 ? 40.63919 7.08423   -20.62651 1.000 17.27231 ? 404 THR A CA  1 
ATOM   3204 C  C   . THR A  1 405 ? 39.64566 6.18385   -21.34857 1.000 17.21388 ? 404 THR A C   1 
ATOM   3205 O  O   . THR A  1 405 ? 39.94063 5.01193   -21.60833 1.000 22.04661 ? 404 THR A O   1 
ATOM   3206 C  CB  . THR A  1 405 ? 41.87255 7.33880   -21.49222 1.000 24.04535 ? 404 THR A CB  1 
ATOM   3207 O  OG1 . THR A  1 405 ? 42.72160 8.29543   -20.84552 1.000 21.39664 ? 404 THR A OG1 1 
ATOM   3208 C  CG2 . THR A  1 405 ? 41.46676 7.86622   -22.85772 1.000 21.23870 ? 404 THR A CG2 1 
ATOM   3209 N  N   . GLU A  1 406 ? 38.47090 6.72561   -21.65788 1.000 13.08210 ? 405 GLU A N   1 
ATOM   3210 C  CA  . GLU A  1 406 ? 37.38899 5.96243   -22.25867 1.000 12.72641 ? 405 GLU A CA  1 
ATOM   3211 C  C   . GLU A  1 406 ? 36.93373 6.61583   -23.55570 1.000 14.10120 ? 405 GLU A C   1 
ATOM   3212 O  O   . GLU A  1 406 ? 37.09128 7.82374   -23.75221 1.000 15.75285 ? 405 GLU A O   1 
ATOM   3213 C  CB  . GLU A  1 406 ? 36.19016 5.84601   -21.30481 1.000 14.29290 ? 405 GLU A CB  1 
ATOM   3214 C  CG  . GLU A  1 406 ? 36.52999 5.35408   -19.91144 1.000 16.51185 ? 405 GLU A CG  1 
ATOM   3215 C  CD  . GLU A  1 406 ? 35.29327 5.03178   -19.09437 1.000 14.82192 ? 405 GLU A CD  1 
ATOM   3216 O  OE1 . GLU A  1 406 ? 34.22674 5.62203   -19.36723 1.000 18.71628 ? 405 GLU A OE1 1 
ATOM   3217 O  OE2 . GLU A  1 406 ? 35.38432 4.18130   -18.18396 1.000 16.05563 ? 405 GLU A OE2 1 
ATOM   3218 N  N   . ILE A  1 407 ? 36.36945 5.79762   -24.44156 1.000 15.40365 ? 406 ILE A N   1 
ATOM   3219 C  CA  . ILE A  1 407 ? 35.66498 6.27042   -25.62824 1.000 15.51894 ? 406 ILE A CA  1 
ATOM   3220 C  C   . ILE A  1 407 ? 34.18181 5.97865   -25.43653 1.000 16.93686 ? 406 ILE A C   1 
ATOM   3221 O  O   . ILE A  1 407 ? 33.77719 4.81453   -25.31211 1.000 13.27499 ? 406 ILE A O   1 
ATOM   3222 C  CB  . ILE A  1 407 ? 36.19045 5.61893   -26.91658 1.000 15.66875 ? 406 ILE A CB  1 
ATOM   3223 C  CG1 . ILE A  1 407 ? 37.53537 6.21985   -27.31448 1.000 18.33498 ? 406 ILE A CG1 1 
ATOM   3224 C  CG2 . ILE A  1 407 ? 35.18969 5.81740   -28.04833 1.000 16.48155 ? 406 ILE A CG2 1 
ATOM   3225 C  CD1 . ILE A  1 407 ? 38.21528 5.49966   -28.45281 1.000 16.92068 ? 406 ILE A CD1 1 
ATOM   3226 N  N   . TRP A  1 408 ? 33.37184 7.03152   -25.40868 1.000 13.49335 ? 407 TRP A N   1 
ATOM   3227 C  CA  . TRP A  1 408 ? 31.92500 6.89793   -25.30836 1.000 13.24697 ? 407 TRP A CA  1 
ATOM   3228 C  C   . TRP A  1 408 ? 31.32404 6.96736   -26.70517 1.000 14.75441 ? 407 TRP A C   1 
ATOM   3229 O  O   . TRP A  1 408 ? 31.56492 7.93067   -27.44050 1.000 17.17930 ? 407 TRP A O   1 
ATOM   3230 C  CB  . TRP A  1 408 ? 31.32260 7.98790   -24.42339 1.000 13.35428 ? 407 TRP A CB  1 
ATOM   3231 C  CG  . TRP A  1 408 ? 31.60708 7.83372   -22.96616 1.000 10.17075 ? 407 TRP A CG  1 
ATOM   3232 C  CD1 . TRP A  1 408 ? 32.66158 7.18268   -22.39661 1.000 11.59462 ? 407 TRP A CD1 1 
ATOM   3233 C  CD2 . TRP A  1 408 ? 30.81540 8.33946   -21.88564 1.000 10.57482 ? 407 TRP A CD2 1 
ATOM   3234 N  NE1 . TRP A  1 408 ? 32.57837 7.25688   -21.02676 1.000 13.27842 ? 407 TRP A NE1 1 
ATOM   3235 C  CE2 . TRP A  1 408 ? 31.45242 7.96118   -20.68836 1.000 13.54107 ? 407 TRP A CE2 1 
ATOM   3236 C  CE3 . TRP A  1 408 ? 29.62907 9.07636   -21.81520 1.000 8.04326  ? 407 TRP A CE3 1 
ATOM   3237 C  CZ2 . TRP A  1 408 ? 30.94399 8.29588   -19.43552 1.000 9.64752  ? 407 TRP A CZ2 1 
ATOM   3238 C  CZ3 . TRP A  1 408 ? 29.12495 9.40458   -20.57219 1.000 9.94147  ? 407 TRP A CZ3 1 
ATOM   3239 C  CH2 . TRP A  1 408 ? 29.78197 9.01547   -19.39867 1.000 10.08894 ? 407 TRP A CH2 1 
ATOM   3240 N  N   . SER A  1 409 ? 30.54755 5.95046   -27.06789 1.000 16.18886 ? 408 SER A N   1 
ATOM   3241 C  CA  . SER A  1 409 ? 29.78041 5.95231   -28.30830 1.000 16.51203 ? 408 SER A CA  1 
ATOM   3242 C  C   . SER A  1 409 ? 28.34679 6.34203   -27.96685 1.000 16.58477 ? 408 SER A C   1 
ATOM   3243 O  O   . SER A  1 409 ? 27.61506 5.56372   -27.34605 1.000 13.81722 ? 408 SER A O   1 
ATOM   3244 C  CB  . SER A  1 409 ? 29.84104 4.59098   -28.99724 1.000 13.81178 ? 408 SER A CB  1 
ATOM   3245 O  OG  . SER A  1 409 ? 31.15786 4.30475   -29.43695 1.000 13.03841 ? 408 SER A OG  1 
ATOM   3246 N  N   . ILE A  1 410 ? 27.95388 7.54859   -28.36062 1.000 12.61287 ? 409 ILE A N   1 
ATOM   3247 C  CA  . ILE A  1 410 ? 26.64499 8.09965   -28.03269 1.000 16.73580 ? 409 ILE A CA  1 
ATOM   3248 C  C   . ILE A  1 410 ? 25.73786 7.88542   -29.23752 1.000 14.74561 ? 409 ILE A C   1 
ATOM   3249 O  O   . ILE A  1 410 ? 25.95701 8.46383   -30.30688 1.000 11.84026 ? 409 ILE A O   1 
ATOM   3250 C  CB  . ILE A  1 410 ? 26.73988 9.58068   -27.64657 1.000 17.65311 ? 409 ILE A CB  1 
ATOM   3251 C  CG1 . ILE A  1 410 ? 27.85399 9.77851   -26.61574 1.000 16.14844 ? 409 ILE A CG1 1 
ATOM   3252 C  CG2 . ILE A  1 410 ? 25.41204 10.07095  -27.08983 1.000 11.94633 ? 409 ILE A CG2 1 
ATOM   3253 C  CD1 . ILE A  1 410 ? 28.03981 11.21371  -26.17358 1.000 12.56542 ? 409 ILE A CD1 1 
ATOM   3254 N  N   . ILE A  1 411 ? 24.71156 7.06144   -29.05962 1.000 15.64715 ? 410 ILE A N   1 
ATOM   3255 C  CA  . ILE A  1 411 ? 23.86494 6.59035   -30.14871 1.000 11.18069 ? 410 ILE A CA  1 
ATOM   3256 C  C   . ILE A  1 411 ? 22.53919 7.33835   -30.08513 1.000 16.13826 ? 410 ILE A C   1 
ATOM   3257 O  O   . ILE A  1 411 ? 21.71598 7.08981   -29.19747 1.000 15.80874 ? 410 ILE A O   1 
ATOM   3258 C  CB  . ILE A  1 411 ? 23.65303 5.07544   -30.06341 1.000 13.43483 ? 410 ILE A CB  1 
ATOM   3259 C  CG1 . ILE A  1 411 ? 25.00091 4.35417   -30.11116 1.000 18.11020 ? 410 ILE A CG1 1 
ATOM   3260 C  CG2 . ILE A  1 411 ? 22.74457 4.61001   -31.17511 1.000 19.36278 ? 410 ILE A CG2 1 
ATOM   3261 C  CD1 . ILE A  1 411 ? 24.96274 2.96094   -29.54367 1.000 18.14143 ? 410 ILE A CD1 1 
ATOM   3262 N  N   . ASN A  1 412 ? 22.31916 8.24458   -31.03606 1.000 14.84400 ? 411 ASN A N   1 
ATOM   3263 C  CA  . ASN A  1 412 ? 21.11661 9.07505   -31.07394 1.000 16.68330 ? 411 ASN A CA  1 
ATOM   3264 C  C   . ASN A  1 412 ? 20.13147 8.45682   -32.05945 1.000 18.69211 ? 411 ASN A C   1 
ATOM   3265 O  O   . ASN A  1 412 ? 20.26973 8.61327   -33.27487 1.000 18.49617 ? 411 ASN A O   1 
ATOM   3266 C  CB  . ASN A  1 412 ? 21.46070 10.51069  -31.45665 1.000 13.09102 ? 411 ASN A CB  1 
ATOM   3267 C  CG  . ASN A  1 412 ? 20.25302 11.43282  -31.42534 1.000 18.07641 ? 411 ASN A CG  1 
ATOM   3268 O  OD1 . ASN A  1 412 ? 19.16619 11.04254  -30.99749 1.000 20.67543 ? 411 ASN A OD1 1 
ATOM   3269 N  ND2 . ASN A  1 412 ? 20.44312 12.66927  -31.87238 1.000 15.81459 ? 411 ASN A ND2 1 
ATOM   3270 N  N   . ALA A  1 413 ? 19.12858 7.75854   -31.52827 1.000 16.34144 ? 412 ALA A N   1 
ATOM   3271 C  CA  . ALA A  1 413 ? 18.05222 7.19514   -32.32910 1.000 21.51658 ? 412 ALA A CA  1 
ATOM   3272 C  C   . ALA A  1 413 ? 16.82951 8.10466   -32.37277 1.000 29.48994 ? 412 ALA A C   1 
ATOM   3273 O  O   . ALA A  1 413 ? 15.72837 7.64034   -32.68678 1.000 34.33567 ? 412 ALA A O   1 
ATOM   3274 C  CB  . ALA A  1 413 ? 17.66778 5.81284   -31.80081 1.000 26.58777 ? 412 ALA A CB  1 
ATOM   3275 N  N   . GLY A  1 414 ? 17.00278 9.39142   -32.06375 1.000 29.05289 ? 413 GLY A N   1 
ATOM   3276 C  CA  . GLY A  1 414 ? 15.91417 10.34075  -32.06149 1.000 24.97122 ? 413 GLY A CA  1 
ATOM   3277 C  C   . GLY A  1 414 ? 15.82955 11.14350  -33.35319 1.000 29.47056 ? 413 GLY A C   1 
ATOM   3278 O  O   . GLY A  1 414 ? 16.57740 10.94389  -34.30779 1.000 15.55172 ? 413 GLY A O   1 
ATOM   3279 N  N   . ARG A  1 415 ? 14.88533 12.08364  -33.35716 1.000 34.44066 ? 414 ARG A N   1 
ATOM   3280 C  CA  . ARG A  1 415 ? 14.60200 12.87840  -34.54452 1.000 25.04323 ? 414 ARG A CA  1 
ATOM   3281 C  C   . ARG A  1 415 ? 15.48904 14.11030  -34.66022 1.000 26.46646 ? 414 ARG A C   1 
ATOM   3282 O  O   . ARG A  1 415 ? 15.72304 14.59001  -35.77593 1.000 28.10745 ? 414 ARG A O   1 
ATOM   3283 C  CB  . ARG A  1 415 ? 13.12852 13.30405  -34.54887 1.000 34.10747 ? 414 ARG A CB  1 
ATOM   3284 C  CG  . ARG A  1 415 ? 12.20682 12.32427  -33.82609 1.000 48.37110 ? 414 ARG A CG  1 
ATOM   3285 C  CD  . ARG A  1 415 ? 10.77938 12.34059  -34.36794 1.000 57.86479 ? 414 ARG A CD  1 
ATOM   3286 N  NE  . ARG A  1 415 ? 9.92941  13.35142  -33.74705 1.000 59.10146 ? 414 ARG A NE  1 
ATOM   3287 C  CZ  . ARG A  1 415 ? 9.20788  13.15634  -32.65063 1.000 59.70499 ? 414 ARG A CZ  1 
ATOM   3288 N  NH1 . ARG A  1 415 ? 9.25678  12.01404  -31.98440 1.000 49.88175 ? 414 ARG A NH1 1 
ATOM   3289 N  NH2 . ARG A  1 415 ? 8.41636  14.13182  -32.21197 1.000 61.04221 ? 414 ARG A NH2 1 
ATOM   3290 N  N   . ALA A  1 416 ? 15.99896 14.62753  -33.54321 1.000 23.74160 ? 415 ALA A N   1 
ATOM   3291 C  CA  . ALA A  1 416 ? 16.72111 15.89067  -33.54333 1.000 19.51699 ? 415 ALA A CA  1 
ATOM   3292 C  C   . ALA A  1 416 ? 17.99216 15.76744  -32.71407 1.000 18.13974 ? 415 ALA A C   1 
ATOM   3293 O  O   . ALA A  1 416 ? 18.24991 14.74797  -32.06851 1.000 19.93733 ? 415 ALA A O   1 
ATOM   3294 C  CB  . ALA A  1 416 ? 15.84596 17.03278  -33.01332 1.000 13.65714 ? 415 ALA A CB  1 
ATOM   3295 N  N   . ILE A  1 417 ? 18.78419 16.84139  -32.73514 1.000 19.22618 ? 416 ILE A N   1 
ATOM   3296 C  CA  . ILE A  1 417 ? 20.07009 16.86428  -32.04907 1.000 18.03230 ? 416 ILE A CA  1 
ATOM   3297 C  C   . ILE A  1 417 ? 19.86148 16.81900  -30.54099 1.000 13.46796 ? 416 ILE A C   1 
ATOM   3298 O  O   . ILE A  1 417 ? 18.90098 17.38960  -30.00692 1.000 17.47695 ? 416 ILE A O   1 
ATOM   3299 C  CB  . ILE A  1 417 ? 20.86350 18.11741  -32.46314 1.000 14.12582 ? 416 ILE A CB  1 
ATOM   3300 C  CG1 . ILE A  1 417 ? 21.10367 18.12687  -33.97381 1.000 9.74798  ? 416 ILE A CG1 1 
ATOM   3301 C  CG2 . ILE A  1 417 ? 22.18925 18.20586  -31.71830 1.000 12.75270 ? 416 ILE A CG2 1 
ATOM   3302 C  CD1 . ILE A  1 417 ? 21.83160 19.36018  -34.46374 1.000 7.02996  ? 416 ILE A CD1 1 
ATOM   3303 N  N   . HIS A  1 418 ? 20.75993 16.12522  -29.84678 1.000 15.32948 ? 417 HIS A N   1 
ATOM   3304 C  CA  . HIS A  1 418 ? 20.83529 16.15781  -28.39239 1.000 14.92495 ? 417 HIS A CA  1 
ATOM   3305 C  C   . HIS A  1 418 ? 22.19218 16.71751  -27.98665 1.000 14.79136 ? 417 HIS A C   1 
ATOM   3306 O  O   . HIS A  1 418 ? 23.22710 16.11176  -28.31575 1.000 15.52999 ? 417 HIS A O   1 
ATOM   3307 C  CB  . HIS A  1 418 ? 20.63717 14.76393  -27.79277 1.000 12.18303 ? 417 HIS A CB  1 
ATOM   3308 C  CG  . HIS A  1 418 ? 19.24995 14.22437  -27.94865 1.000 16.05177 ? 417 HIS A CG  1 
ATOM   3309 N  ND1 . HIS A  1 418 ? 18.22113 14.55799  -27.09434 1.000 16.43058 ? 417 HIS A ND1 1 
ATOM   3310 C  CD2 . HIS A  1 418 ? 18.72500 13.36152  -28.85049 1.000 18.08573 ? 417 HIS A CD2 1 
ATOM   3311 C  CE1 . HIS A  1 418 ? 17.12032 13.93032  -27.46783 1.000 17.31126 ? 417 HIS A CE1 1 
ATOM   3312 N  NE2 . HIS A  1 418 ? 17.39906 13.19760  -28.53096 1.000 18.25939 ? 417 HIS A NE2 1 
ATOM   3313 N  N   . PRO A  1 419 ? 22.25439 17.86109  -27.30203 1.000 12.23843 ? 418 PRO A N   1 
ATOM   3314 C  CA  . PRO A  1 419 ? 23.54397 18.34064  -26.78629 1.000 14.38354 ? 418 PRO A CA  1 
ATOM   3315 C  C   . PRO A  1 419 ? 23.91676 17.65391  -25.48134 1.000 14.60534 ? 418 PRO A C   1 
ATOM   3316 O  O   . PRO A  1 419 ? 23.49323 18.07705  -24.40059 1.000 11.89524 ? 418 PRO A O   1 
ATOM   3317 C  CB  . PRO A  1 419 ? 23.30421 19.84180  -26.59230 1.000 12.98245 ? 418 PRO A CB  1 
ATOM   3318 C  CG  . PRO A  1 419 ? 21.84068 19.94123  -26.30615 1.000 11.52793 ? 418 PRO A CG  1 
ATOM   3319 C  CD  . PRO A  1 419 ? 21.17495 18.84247  -27.10122 1.000 11.90000 ? 418 PRO A CD  1 
ATOM   3320 N  N   . ILE A  1 420 ? 24.70255 16.58545  -25.57086 1.000 12.94469 ? 419 ILE A N   1 
ATOM   3321 C  CA  . ILE A  1 420 ? 25.04329 15.78849  -24.39749 1.000 13.37196 ? 419 ILE A CA  1 
ATOM   3322 C  C   . ILE A  1 420 ? 26.20362 16.44311  -23.65962 1.000 10.84351 ? 419 ILE A C   1 
ATOM   3323 O  O   . ILE A  1 420 ? 27.19684 16.85436  -24.27028 1.000 12.65622 ? 419 ILE A O   1 
ATOM   3324 C  CB  . ILE A  1 420 ? 25.38282 14.34479  -24.80318 1.000 11.25374 ? 419 ILE A CB  1 
ATOM   3325 C  CG1 . ILE A  1 420 ? 24.24589 13.74876  -25.63753 1.000 13.03254 ? 419 ILE A CG1 1 
ATOM   3326 C  CG2 . ILE A  1 420 ? 25.64508 13.49327  -23.57222 1.000 9.01035  ? 419 ILE A CG2 1 
ATOM   3327 C  CD1 . ILE A  1 420 ? 22.90540 13.75852  -24.93687 1.000 8.32090  ? 419 ILE A CD1 1 
ATOM   3328 N  N   . HIS A  1 421 ? 26.08443 16.53048  -22.33880 1.000 8.49434  ? 420 HIS A N   1 
ATOM   3329 C  CA  . HIS A  1 421 ? 27.07093 17.18598  -21.49471 1.000 8.21366  ? 420 HIS A CA  1 
ATOM   3330 C  C   . HIS A  1 421 ? 27.55871 16.22863  -20.41573 1.000 10.39263 ? 420 HIS A C   1 
ATOM   3331 O  O   . HIS A  1 421 ? 26.76226 15.51292  -19.79885 1.000 12.40548 ? 420 HIS A O   1 
ATOM   3332 C  CB  . HIS A  1 421 ? 26.48016 18.44565  -20.85054 1.000 13.96001 ? 420 HIS A CB  1 
ATOM   3333 C  CG  . HIS A  1 421 ? 27.34097 19.03918  -19.77900 1.000 15.20138 ? 420 HIS A CG  1 
ATOM   3334 N  ND1 . HIS A  1 421 ? 28.64196 19.43671  -20.00270 1.000 15.26223 ? 420 HIS A ND1 1 
ATOM   3335 C  CD2 . HIS A  1 421 ? 27.08585 19.30391  -18.47618 1.000 10.12500 ? 420 HIS A CD2 1 
ATOM   3336 C  CE1 . HIS A  1 421 ? 29.15102 19.92029  -18.88383 1.000 12.57640 ? 420 HIS A CE1 1 
ATOM   3337 N  NE2 . HIS A  1 421 ? 28.22714 19.85169  -17.94279 1.000 14.18513 ? 420 HIS A NE2 1 
ATOM   3338 N  N   . LEU A  1 422 ? 28.87112 16.22028  -20.19428 1.000 10.57805 ? 421 LEU A N   1 
ATOM   3339 C  CA  . LEU A  1 422 ? 29.49544 15.45710  -19.12177 1.000 10.51642 ? 421 LEU A CA  1 
ATOM   3340 C  C   . LEU A  1 422 ? 30.11701 16.41193  -18.11251 1.000 9.40886  ? 421 LEU A C   1 
ATOM   3341 O  O   . LEU A  1 422 ? 30.73213 17.41286  -18.49101 1.000 16.16963 ? 421 LEU A O   1 
ATOM   3342 C  CB  . LEU A  1 422 ? 30.57247 14.50793  -19.65963 1.000 8.36082  ? 421 LEU A CB  1 
ATOM   3343 C  CG  . LEU A  1 422 ? 30.17581 13.08668  -20.07255 1.000 9.86435  ? 421 LEU A CG  1 
ATOM   3344 C  CD1 . LEU A  1 422 ? 29.28481 13.08813  -21.30728 1.000 9.78746  ? 421 LEU A CD1 1 
ATOM   3345 C  CD2 . LEU A  1 422 ? 31.42008 12.24242  -20.30816 1.000 6.90761  ? 421 LEU A CD2 1 
ATOM   3346 N  N   . HIS A  1 423 ? 29.95674 16.10122  -16.82999 1.000 9.46326  ? 422 HIS A N   1 
ATOM   3347 C  CA  . HIS A  1 423 ? 30.54388 16.92637  -15.78762 1.000 13.60923 ? 422 HIS A CA  1 
ATOM   3348 C  C   . HIS A  1 423 ? 32.02140 16.58562  -15.59979 1.000 12.26560 ? 422 HIS A C   1 
ATOM   3349 O  O   . HIS A  1 423 ? 32.55218 15.63976  -16.18881 1.000 14.92815 ? 422 HIS A O   1 
ATOM   3350 C  CB  . HIS A  1 423 ? 29.78918 16.75363  -14.46899 1.000 14.30194 ? 422 HIS A CB  1 
ATOM   3351 C  CG  . HIS A  1 423 ? 28.46150 17.44528  -14.43461 1.000 13.93209 ? 422 HIS A CG  1 
ATOM   3352 N  ND1 . HIS A  1 423 ? 27.96978 18.05354  -13.29952 1.000 14.59938 ? 422 HIS A ND1 1 
ATOM   3353 C  CD2 . HIS A  1 423 ? 27.52233 17.62431  -15.39380 1.000 14.17300 ? 422 HIS A CD2 1 
ATOM   3354 C  CE1 . HIS A  1 423 ? 26.78761 18.58208  -13.56224 1.000 16.07166 ? 422 HIS A CE1 1 
ATOM   3355 N  NE2 . HIS A  1 423 ? 26.49099 18.33201  -14.82506 1.000 13.65569 ? 422 HIS A NE2 1 
ATOM   3356 N  N   . LEU A  1 424 ? 32.68817 17.39561  -14.77442 1.000 10.34739 ? 423 LEU A N   1 
ATOM   3357 C  CA  . LEU A  1 424 ? 34.07802 17.19129  -14.37362 1.000 14.64457 ? 423 LEU A CA  1 
ATOM   3358 C  C   . LEU A  1 424 ? 35.06590 17.33202  -15.52687 1.000 14.71010 ? 423 LEU A C   1 
ATOM   3359 O  O   . LEU A  1 424 ? 35.94984 18.19396  -15.48735 1.000 16.75602 ? 423 LEU A O   1 
ATOM   3360 C  CB  . LEU A  1 424 ? 34.25391 15.81896  -13.71459 1.000 14.63037 ? 423 LEU A CB  1 
ATOM   3361 C  CG  . LEU A  1 424 ? 35.70019 15.39786  -13.44074 1.000 15.61199 ? 423 LEU A CG  1 
ATOM   3362 C  CD1 . LEU A  1 424 ? 36.33561 16.29461  -12.38915 1.000 15.48690 ? 423 LEU A CD1 1 
ATOM   3363 C  CD2 . LEU A  1 424 ? 35.77393 13.93646  -13.02432 1.000 17.10442 ? 423 LEU A CD2 1 
ATOM   3364 N  N   . VAL A  1 425 ? 34.93213 16.49456  -16.55331 1.000 14.32582 ? 424 VAL A N   1 
ATOM   3365 C  CA  . VAL A  1 425 ? 35.98524 16.33795  -17.55117 1.000 16.20105 ? 424 VAL A CA  1 
ATOM   3366 C  C   . VAL A  1 425 ? 35.78978 17.26819  -18.74073 1.000 19.51681 ? 424 VAL A C   1 
ATOM   3367 O  O   . VAL A  1 425 ? 34.72080 17.86217  -18.92136 1.000 19.98792 ? 424 VAL A O   1 
ATOM   3368 C  CB  . VAL A  1 425 ? 36.06538 14.87759  -18.03119 1.000 19.70577 ? 424 VAL A CB  1 
ATOM   3369 C  CG1 . VAL A  1 425 ? 36.33833 13.94801  -16.86086 1.000 20.71397 ? 424 VAL A CG1 1 
ATOM   3370 C  CG2 . VAL A  1 425 ? 34.78026 14.48660  -18.74774 1.000 12.50869 ? 424 VAL A CG2 1 
ATOM   3371 N  N   . GLN A  1 426 ? 36.84054 17.40422  -19.54704 1.000 18.68547 ? 425 GLN A N   1 
ATOM   3372 C  CA  . GLN A  1 426 ? 36.77768 17.99276  -20.87836 1.000 13.80940 ? 425 GLN A CA  1 
ATOM   3373 C  C   . GLN A  1 426 ? 37.22049 16.91997  -21.86172 1.000 12.92940 ? 425 GLN A C   1 
ATOM   3374 O  O   . GLN A  1 426 ? 38.30797 16.35384  -21.71254 1.000 16.65025 ? 425 GLN A O   1 
ATOM   3375 C  CB  . GLN A  1 426 ? 37.67172 19.23067  -20.98646 1.000 17.20235 ? 425 GLN A CB  1 
ATOM   3376 C  CG  . GLN A  1 426 ? 37.24264 20.39750  -20.11505 1.000 16.05799 ? 425 GLN A CG  1 
ATOM   3377 C  CD  . GLN A  1 426 ? 35.99485 21.08420  -20.63294 1.000 17.01159 ? 425 GLN A CD  1 
ATOM   3378 O  OE1 . GLN A  1 426 ? 35.71404 21.06412  -21.83098 1.000 13.69460 ? 425 GLN A OE1 1 
ATOM   3379 N  NE2 . GLN A  1 426 ? 35.23692 21.69604  -19.72979 1.000 15.90066 ? 425 GLN A NE2 1 
ATOM   3380 N  N   . PHE A  1 427 ? 36.38321 16.63004  -22.85053 1.000 15.10743 ? 426 PHE A N   1 
ATOM   3381 C  CA  . PHE A  1 427 ? 36.63414 15.53282  -23.77335 1.000 11.23331 ? 426 PHE A CA  1 
ATOM   3382 C  C   . PHE A  1 427 ? 36.98876 16.06704  -25.15897 1.000 9.91186  ? 426 PHE A C   1 
ATOM   3383 O  O   . PHE A  1 427 ? 36.97007 17.27271  -25.41597 1.000 13.20947 ? 426 PHE A O   1 
ATOM   3384 C  CB  . PHE A  1 427 ? 35.42536 14.59187  -23.83270 1.000 10.30689 ? 426 PHE A CB  1 
ATOM   3385 C  CG  . PHE A  1 427 ? 34.13514 15.26561  -24.21720 1.000 12.62307 ? 426 PHE A CG  1 
ATOM   3386 C  CD1 . PHE A  1 427 ? 33.88495 15.63135  -25.53216 1.000 8.70514  ? 426 PHE A CD1 1 
ATOM   3387 C  CD2 . PHE A  1 427 ? 33.15880 15.50446  -23.26661 1.000 10.37852 ? 426 PHE A CD2 1 
ATOM   3388 C  CE1 . PHE A  1 427 ? 32.69775 16.24195  -25.88370 1.000 9.38242  ? 426 PHE A CE1 1 
ATOM   3389 C  CE2 . PHE A  1 427 ? 31.96661 16.10956  -23.61553 1.000 12.09941 ? 426 PHE A CE2 1 
ATOM   3390 C  CZ  . PHE A  1 427 ? 31.73685 16.47963  -24.92513 1.000 8.34379  ? 426 PHE A CZ  1 
ATOM   3391 N  N   . LEU A  1 428 ? 37.31349 15.14192  -26.05869 1.000 13.27192 ? 427 LEU A N   1 
ATOM   3392 C  CA  . LEU A  1 428 ? 37.56844 15.44109  -27.46010 1.000 11.29409 ? 427 LEU A CA  1 
ATOM   3393 C  C   . LEU A  1 428 ? 36.57035 14.68553  -28.32455 1.000 14.33152 ? 427 LEU A C   1 
ATOM   3394 O  O   . LEU A  1 428 ? 36.25468 13.52210  -28.04926 1.000 12.00178 ? 427 LEU A O   1 
ATOM   3395 C  CB  . LEU A  1 428 ? 38.99585 15.05707  -27.86389 1.000 10.20965 ? 427 LEU A CB  1 
ATOM   3396 C  CG  . LEU A  1 428 ? 40.14270 15.75674  -27.13243 1.000 16.19452 ? 427 LEU A CG  1 
ATOM   3397 C  CD1 . LEU A  1 428 ? 41.47463 15.15095  -27.53742 1.000 13.10778 ? 427 LEU A CD1 1 
ATOM   3398 C  CD2 . LEU A  1 428 ? 40.12573 17.25257  -27.40784 1.000 15.64213 ? 427 LEU A CD2 1 
ATOM   3399 N  N   . ILE A  1 429 ? 36.07773 15.34459  -29.36870 1.000 11.95704 ? 428 ILE A N   1 
ATOM   3400 C  CA  . ILE A  1 429 ? 35.13106 14.71907  -30.28558 1.000 11.49142 ? 428 ILE A CA  1 
ATOM   3401 C  C   . ILE A  1 429 ? 35.91255 13.94780  -31.34160 1.000 12.49909 ? 428 ILE A C   1 
ATOM   3402 O  O   . ILE A  1 429 ? 36.78104 14.50826  -32.01817 1.000 12.45518 ? 428 ILE A O   1 
ATOM   3403 C  CB  . ILE A  1 429 ? 34.21024 15.76455  -30.93128 1.000 13.71716 ? 428 ILE A CB  1 
ATOM   3404 C  CG1 . ILE A  1 429 ? 33.53665 16.61396  -29.85264 1.000 8.17937  ? 428 ILE A CG1 1 
ATOM   3405 C  CG2 . ILE A  1 429 ? 33.17086 15.08277  -31.80653 1.000 9.58899  ? 428 ILE A CG2 1 
ATOM   3406 C  CD1 . ILE A  1 429 ? 32.72010 17.76100  -30.40721 1.000 10.41860 ? 428 ILE A CD1 1 
ATOM   3407 N  N   . LEU A  1 430 ? 35.60595 12.65808  -31.48341 1.000 13.84072 ? 429 LEU A N   1 
ATOM   3408 C  CA  . LEU A  1 430 ? 36.31766 11.79350  -32.42162 1.000 10.68079 ? 429 LEU A CA  1 
ATOM   3409 C  C   . LEU A  1 430 ? 35.70976 11.85015  -33.82080 1.000 12.95194 ? 429 LEU A C   1 
ATOM   3410 O  O   . LEU A  1 430 ? 36.38031 12.25643  -34.77462 1.000 23.20459 ? 429 LEU A O   1 
ATOM   3411 C  CB  . LEU A  1 430 ? 36.33476 10.35223  -31.90160 1.000 16.87186 ? 429 LEU A CB  1 
ATOM   3412 C  CG  . LEU A  1 430 ? 37.57316 9.92392   -31.11199 1.000 18.89343 ? 429 LEU A CG  1 
ATOM   3413 C  CD1 . LEU A  1 430 ? 37.84228 10.87828  -29.96437 1.000 20.60855 ? 429 LEU A CD1 1 
ATOM   3414 C  CD2 . LEU A  1 430 ? 37.41142 8.50270   -30.59874 1.000 25.05213 ? 429 LEU A CD2 1 
ATOM   3415 N  N   . ASP A  1 431 ? 34.44983 11.44296  -33.95910 1.000 8.92230  ? 430 ASP A N   1 
ATOM   3416 C  CA  . ASP A  1 431 ? 33.80275 11.41028  -35.26606 1.000 16.30286 ? 430 ASP A CA  1 
ATOM   3417 C  C   . ASP A  1 431 ? 32.30573 11.20063  -35.07894 1.000 16.90774 ? 430 ASP A C   1 
ATOM   3418 O  O   . ASP A  1 431 ? 31.83844 10.83147  -33.99824 1.000 18.30942 ? 430 ASP A O   1 
ATOM   3419 C  CB  . ASP A  1 431 ? 34.39914 10.31632  -36.16182 1.000 16.76223 ? 430 ASP A CB  1 
ATOM   3420 C  CG  . ASP A  1 431 ? 34.55824 8.98420   -35.44149 1.000 22.31770 ? 430 ASP A CG  1 
ATOM   3421 O  OD1 . ASP A  1 431 ? 33.88625 8.76518   -34.41133 1.000 19.62012 ? 430 ASP A OD1 1 
ATOM   3422 O  OD2 . ASP A  1 431 ? 35.36904 8.15460   -35.90477 1.000 25.83629 ? 430 ASP A OD2 1 
ATOM   3423 N  N   . HIS A  1 432 ? 31.55995 11.45467  -36.15340 1.000 14.15470 ? 431 HIS A N   1 
ATOM   3424 C  CA  . HIS A  1 432 ? 30.14332 11.13597  -36.24556 1.000 14.99852 ? 431 HIS A CA  1 
ATOM   3425 C  C   . HIS A  1 432 ? 29.93470 10.14625  -37.38330 1.000 13.72233 ? 431 HIS A C   1 
ATOM   3426 O  O   . HIS A  1 432 ? 30.62303 10.20241  -38.40633 1.000 14.61139 ? 431 HIS A O   1 
ATOM   3427 C  CB  . HIS A  1 432 ? 29.28659 12.38681  -36.49622 1.000 14.94504 ? 431 HIS A CB  1 
ATOM   3428 C  CG  . HIS A  1 432 ? 29.57583 13.52259  -35.56508 1.000 19.93538 ? 431 HIS A CG  1 
ATOM   3429 N  ND1 . HIS A  1 432 ? 28.96291 13.65450  -34.33759 1.000 21.03914 ? 431 HIS A ND1 1 
ATOM   3430 C  CD2 . HIS A  1 432 ? 30.40308 14.58773  -35.68872 1.000 17.97868 ? 431 HIS A CD2 1 
ATOM   3431 C  CE1 . HIS A  1 432 ? 29.40572 14.74765  -33.74189 1.000 18.32860 ? 431 HIS A CE1 1 
ATOM   3432 N  NE2 . HIS A  1 432 ? 30.28058 15.33212  -34.54052 1.000 15.18704 ? 431 HIS A NE2 1 
ATOM   3433 N  N   . ARG A  1 433 ? 28.97276 9.23961   -37.20645 1.000 12.37873 ? 432 ARG A N   1 
ATOM   3434 C  CA  . ARG A  1 433 ? 28.74067 8.22273   -38.21510 1.000 11.09503 ? 432 ARG A CA  1 
ATOM   3435 C  C   . ARG A  1 433 ? 27.29061 7.75625   -38.17195 1.000 10.41951 ? 432 ARG A C   1 
ATOM   3436 O  O   . ARG A  1 433 ? 26.78214 7.45636   -37.08000 1.000 10.16058 ? 432 ARG A O   1 
ATOM   3437 C  CB  . ARG A  1 433 ? 29.68146 7.03225   -38.01796 1.000 14.95501 ? 432 ARG A CB  1 
ATOM   3438 C  CG  . ARG A  1 433 ? 29.68545 6.05232   -39.17616 1.000 15.37678 ? 432 ARG A CG  1 
ATOM   3439 C  CD  . ARG A  1 433 ? 30.69425 4.94061   -38.96956 1.000 13.39927 ? 432 ARG A CD  1 
ATOM   3440 N  NE  . ARG A  1 433 ? 30.62587 3.95999   -40.04593 1.000 17.71846 ? 432 ARG A NE  1 
ATOM   3441 C  CZ  . ARG A  1 433 ? 31.29262 2.81416   -40.06351 1.000 19.11525 ? 432 ARG A CZ  1 
ATOM   3442 N  NH1 . ARG A  1 433 ? 32.09826 2.46703   -39.07254 1.000 15.55973 ? 432 ARG A NH1 1 
ATOM   3443 N  NH2 . ARG A  1 433 ? 31.14430 1.99429   -41.10013 1.000 16.83501 ? 432 ARG A NH2 1 
ATOM   3444 N  N   . PRO A  1 434 ? 26.61097 7.68609   -39.31305 1.000 11.66317 ? 433 PRO A N   1 
ATOM   3445 C  CA  . PRO A  1 434 ? 25.20763 7.26534   -39.31949 1.000 10.30288 ? 433 PRO A CA  1 
ATOM   3446 C  C   . PRO A  1 434 ? 25.06648 5.75471   -39.20326 1.000 11.57023 ? 433 PRO A C   1 
ATOM   3447 O  O   . PRO A  1 434 ? 25.96222 4.98484   -39.55585 1.000 12.50960 ? 433 PRO A O   1 
ATOM   3448 C  CB  . PRO A  1 434 ? 24.70324 7.75977   -40.67843 1.000 12.88545 ? 433 PRO A CB  1 
ATOM   3449 C  CG  . PRO A  1 434 ? 25.91572 7.71043   -41.54696 1.000 10.86552 ? 433 PRO A CG  1 
ATOM   3450 C  CD  . PRO A  1 434 ? 27.07951 8.06990   -40.65695 1.000 10.01935 ? 433 PRO A CD  1 
ATOM   3451 N  N   . PHE A  1 435 ? 23.90433 5.33820   -38.70085 1.000 12.35627 ? 434 PHE A N   1 
ATOM   3452 C  CA  . PHE A  1 435 ? 23.61826 3.92579   -38.49374 1.000 18.74803 ? 434 PHE A CA  1 
ATOM   3453 C  C   . PHE A  1 435 ? 22.17333 3.63327   -38.87595 1.000 15.89471 ? 434 PHE A C   1 
ATOM   3454 O  O   . PHE A  1 435 ? 21.38030 4.53773   -39.14868 1.000 22.85613 ? 434 PHE A O   1 
ATOM   3455 C  CB  . PHE A  1 435 ? 23.89356 3.49934   -37.04394 1.000 20.26750 ? 434 PHE A CB  1 
ATOM   3456 C  CG  . PHE A  1 435 ? 22.93888 4.08469   -36.04141 1.000 14.74196 ? 434 PHE A CG  1 
ATOM   3457 C  CD1 . PHE A  1 435 ? 23.11630 5.37280   -35.56377 1.000 15.27413 ? 434 PHE A CD1 1 
ATOM   3458 C  CD2 . PHE A  1 435 ? 21.87318 3.33915   -35.56421 1.000 14.47751 ? 434 PHE A CD2 1 
ATOM   3459 C  CE1 . PHE A  1 435 ? 22.24137 5.91097   -34.63737 1.000 15.59609 ? 434 PHE A CE1 1 
ATOM   3460 C  CE2 . PHE A  1 435 ? 20.99687 3.86989   -34.63808 1.000 17.17810 ? 434 PHE A CE2 1 
ATOM   3461 C  CZ  . PHE A  1 435 ? 21.18090 5.15801   -34.17482 1.000 18.87207 ? 434 PHE A CZ  1 
ATOM   3462 N  N   . ASP A  1 436 ? 21.83878 2.34462   -38.88824 1.000 15.72673 ? 435 ASP A N   1 
ATOM   3463 C  CA  . ASP A  1 436 ? 20.51907 1.87897   -39.30382 1.000 19.22997 ? 435 ASP A CA  1 
ATOM   3464 C  C   . ASP A  1 436 ? 19.54402 2.03721   -38.14218 1.000 22.92354 ? 435 ASP A C   1 
ATOM   3465 O  O   . ASP A  1 436 ? 19.63759 1.32065   -37.13971 1.000 23.74936 ? 435 ASP A O   1 
ATOM   3466 C  CB  . ASP A  1 436 ? 20.59886 0.42650   -39.76685 1.000 22.12931 ? 435 ASP A CB  1 
ATOM   3467 C  CG  . ASP A  1 436 ? 19.39023 -0.00044  -40.57871 1.000 24.11114 ? 435 ASP A CG  1 
ATOM   3468 O  OD1 . ASP A  1 436 ? 18.27853 0.50940   -40.32497 1.000 27.29961 ? 435 ASP A OD1 1 
ATOM   3469 O  OD2 . ASP A  1 436 ? 19.55526 -0.85359  -41.47541 1.000 29.80989 ? 435 ASP A OD2 1 
ATOM   3470 N  N   . ILE A  1 437 ? 18.59874 2.96916   -38.28274 1.000 24.37142 ? 436 ILE A N   1 
ATOM   3471 C  CA  . ILE A  1 437 ? 17.63573 3.22687   -37.21589 1.000 28.03831 ? 436 ILE A CA  1 
ATOM   3472 C  C   . ILE A  1 437 ? 16.69344 2.04251   -37.03936 1.000 34.82504 ? 436 ILE A C   1 
ATOM   3473 O  O   . ILE A  1 437 ? 16.41001 1.62092   -35.91096 1.000 25.11662 ? 436 ILE A O   1 
ATOM   3474 C  CB  . ILE A  1 437 ? 16.86056 4.52495   -37.50357 1.000 31.74426 ? 436 ILE A CB  1 
ATOM   3475 C  CG1 . ILE A  1 437 ? 17.80810 5.72277   -37.49327 1.000 28.74895 ? 436 ILE A CG1 1 
ATOM   3476 C  CG2 . ILE A  1 437 ? 15.74752 4.71899   -36.48623 1.000 43.12210 ? 436 ILE A CG2 1 
ATOM   3477 C  CD1 . ILE A  1 437 ? 18.46310 5.95092   -36.15911 1.000 23.89704 ? 436 ILE A CD1 1 
ATOM   3478 N  N   . GLU A  1 438 ? 16.19008 1.49051   -38.14628 1.000 36.70908 ? 437 GLU A N   1 
ATOM   3479 C  CA  . GLU A  1 438 ? 15.23447 0.39043   -38.05953 1.000 31.82409 ? 437 GLU A CA  1 
ATOM   3480 C  C   . GLU A  1 438 ? 15.86427 -0.83870  -37.41735 1.000 32.65523 ? 437 GLU A C   1 
ATOM   3481 O  O   . GLU A  1 438 ? 15.26311 -1.47177  -36.54235 1.000 39.65162 ? 437 GLU A O   1 
ATOM   3482 C  CB  . GLU A  1 438 ? 14.69010 0.05516   -39.44766 1.000 44.87719 ? 437 GLU A CB  1 
ATOM   3483 C  CG  . GLU A  1 438 ? 13.30545 0.61534   -39.71588 1.000 50.16415 ? 437 GLU A CG  1 
ATOM   3484 C  CD  . GLU A  1 438 ? 12.66819 0.01449   -40.95094 1.000 61.08343 ? 437 GLU A CD  1 
ATOM   3485 O  OE1 . GLU A  1 438 ? 12.86779 0.56551   -42.05428 1.000 56.08588 ? 437 GLU A OE1 1 
ATOM   3486 O  OE2 . GLU A  1 438 ? 11.97646 -1.01794  -40.81768 1.000 70.71002 ? 437 GLU A OE2 1 
ATOM   3487 N  N   . ARG A  1 439 ? 17.07971 -1.19356  -37.84176 1.000 33.40656 ? 438 ARG A N   1 
ATOM   3488 C  CA  . ARG A  1 439 ? 17.76593 -2.32943  -37.23623 1.000 27.66710 ? 438 ARG A CA  1 
ATOM   3489 C  C   . ARG A  1 439 ? 18.03210 -2.08894  -35.75672 1.000 29.97879 ? 438 ARG A C   1 
ATOM   3490 O  O   . ARG A  1 439 ? 18.07604 -3.03990  -34.96923 1.000 41.00831 ? 438 ARG A O   1 
ATOM   3491 C  CB  . ARG A  1 439 ? 19.07836 -2.60441  -37.97201 1.000 22.69869 ? 438 ARG A CB  1 
ATOM   3492 C  CG  . ARG A  1 439 ? 19.58111 -4.03099  -37.84565 1.000 28.78416 ? 438 ARG A CG  1 
ATOM   3493 C  CD  . ARG A  1 439 ? 19.05958 -4.89332  -38.98509 1.000 46.33074 ? 438 ARG A CD  1 
ATOM   3494 N  NE  . ARG A  1 439 ? 19.68583 -4.54316  -40.25500 1.000 49.88322 ? 438 ARG A NE  1 
ATOM   3495 C  CZ  . ARG A  1 439 ? 20.76690 -5.13510  -40.74565 1.000 52.08266 ? 438 ARG A CZ  1 
ATOM   3496 N  NH1 . ARG A  1 439 ? 21.35907 -6.13220  -40.10798 1.000 39.74893 ? 438 ARG A NH1 1 
ATOM   3497 N  NH2 . ARG A  1 439 ? 21.26809 -4.71475  -41.90413 1.000 48.04486 ? 438 ARG A NH2 1 
ATOM   3498 N  N   . TYR A  1 440 ? 18.19504 -0.82584  -35.36165 1.000 26.43720 ? 439 TYR A N   1 
ATOM   3499 C  CA  . TYR A  1 440 ? 18.51543 -0.49584  -33.97806 1.000 25.06352 ? 439 TYR A CA  1 
ATOM   3500 C  C   . TYR A  1 440 ? 17.30886 -0.65753  -33.06035 1.000 34.15684 ? 439 TYR A C   1 
ATOM   3501 O  O   . TYR A  1 440 ? 17.45620 -1.08709  -31.91052 1.000 33.23634 ? 439 TYR A O   1 
ATOM   3502 C  CB  . TYR A  1 440 ? 19.05404 0.93311   -33.90614 1.000 21.48242 ? 439 TYR A CB  1 
ATOM   3503 C  CG  . TYR A  1 440 ? 19.66850 1.30541   -32.57941 1.000 24.06171 ? 439 TYR A CG  1 
ATOM   3504 C  CD1 . TYR A  1 440 ? 20.83548 0.69505   -32.14326 1.000 24.15353 ? 439 TYR A CD1 1 
ATOM   3505 C  CD2 . TYR A  1 440 ? 19.09518 2.28271   -31.77292 1.000 24.71531 ? 439 TYR A CD2 1 
ATOM   3506 C  CE1 . TYR A  1 440 ? 21.41040 1.03427   -30.93936 1.000 20.10542 ? 439 TYR A CE1 1 
ATOM   3507 C  CE2 . TYR A  1 440 ? 19.66317 2.62898   -30.56239 1.000 25.53519 ? 439 TYR A CE2 1 
ATOM   3508 C  CZ  . TYR A  1 440 ? 20.82192 1.99870   -30.15219 1.000 23.72034 ? 439 TYR A CZ  1 
ATOM   3509 O  OH  . TYR A  1 440 ? 21.40361 2.33098   -28.95155 1.000 27.70177 ? 439 TYR A OH  1 
ATOM   3510 N  N   . GLN A  1 441 ? 16.11183 -0.31315  -33.54223 1.000 31.83284 ? 440 GLN A N   1 
ATOM   3511 C  CA  . GLN A  1 441 ? 14.91908 -0.38419  -32.70709 1.000 30.33074 ? 440 GLN A CA  1 
ATOM   3512 C  C   . GLN A  1 441 ? 14.34328 -1.79140  -32.60984 1.000 37.98474 ? 440 GLN A C   1 
ATOM   3513 O  O   . GLN A  1 441 ? 13.63004 -2.08758  -31.64507 1.000 52.44494 ? 440 GLN A O   1 
ATOM   3514 C  CB  . GLN A  1 441 ? 13.84879 0.58061   -33.23069 1.000 39.58260 ? 440 GLN A CB  1 
ATOM   3515 C  CG  . GLN A  1 441 ? 13.50775 0.42349   -34.70895 1.000 42.61639 ? 440 GLN A CG  1 
ATOM   3516 C  CD  . GLN A  1 441 ? 12.52308 -0.70153  -34.97895 1.000 50.34917 ? 440 GLN A CD  1 
ATOM   3517 O  OE1 . GLN A  1 441 ? 11.75842 -1.09808  -34.09888 1.000 57.75403 ? 440 GLN A OE1 1 
ATOM   3518 N  NE2 . GLN A  1 441 ? 12.53985 -1.22282  -36.20116 1.000 46.71255 ? 440 GLN A NE2 1 
ATOM   3519 N  N   . GLU A  1 442 ? 14.63018 -2.66097  -33.57817 1.000 38.48875 ? 441 GLU A N   1 
ATOM   3520 C  CA  . GLU A  1 442 ? 14.09260 -4.01442  -33.57713 1.000 37.66393 ? 441 GLU A CA  1 
ATOM   3521 C  C   . GLU A  1 442 ? 15.06201 -5.04852  -33.02331 1.000 40.48877 ? 441 GLU A C   1 
ATOM   3522 O  O   . GLU A  1 442 ? 14.61648 -6.09315  -32.53601 1.000 49.06948 ? 441 GLU A O   1 
ATOM   3523 C  CB  . GLU A  1 442 ? 13.68487 -4.42183  -34.99918 1.000 34.98817 ? 441 GLU A CB  1 
ATOM   3524 C  CG  . GLU A  1 442 ? 14.85398 -4.58001  -35.95954 1.000 44.10529 ? 441 GLU A CG  1 
ATOM   3525 C  CD  . GLU A  1 442 ? 14.43136 -4.52001  -37.41655 1.000 58.19337 ? 441 GLU A CD  1 
ATOM   3526 O  OE1 . GLU A  1 442 ? 15.31813 -4.55680  -38.29696 1.000 53.11333 ? 441 GLU A OE1 1 
ATOM   3527 O  OE2 . GLU A  1 442 ? 13.21287 -4.44276  -37.68217 1.000 61.50515 ? 441 GLU A OE2 1 
ATOM   3528 N  N   . ASN A  1 443 ? 16.36498 -4.78062  -33.07508 1.000 40.04624 ? 442 ASN A N   1 
ATOM   3529 C  CA  . ASN A  1 443 ? 17.37791 -5.75219  -32.68359 1.000 39.14311 ? 442 ASN A CA  1 
ATOM   3530 C  C   . ASN A  1 443 ? 18.36617 -5.23161  -31.65277 1.000 30.85576 ? 442 ASN A C   1 
ATOM   3531 O  O   . ASN A  1 443 ? 19.03504 -6.04639  -31.00497 1.000 28.03605 ? 442 ASN A O   1 
ATOM   3532 C  CB  . ASN A  1 443 ? 18.16343 -6.22311  -33.91998 1.000 37.95168 ? 442 ASN A CB  1 
ATOM   3533 C  CG  . ASN A  1 443 ? 18.71035 -7.63060  -33.77292 1.000 45.33933 ? 442 ASN A CG  1 
ATOM   3534 O  OD1 . ASN A  1 443 ? 18.80276 -8.16625  -32.66858 1.000 51.61650 ? 442 ASN A OD1 1 
ATOM   3535 N  ND2 . ASN A  1 443 ? 19.08050 -8.23759  -34.89587 1.000 38.51261 ? 442 ASN A ND2 1 
ATOM   3536 N  N   . GLY A  1 444 ? 18.47784 -3.91883  -31.46731 1.000 24.41394 ? 443 GLY A N   1 
ATOM   3537 C  CA  . GLY A  1 444 ? 19.55335 -3.36237  -30.67893 1.000 24.03353 ? 443 GLY A CA  1 
ATOM   3538 C  C   . GLY A  1 444 ? 20.89860 -3.36580  -31.36543 1.000 23.39384 ? 443 GLY A C   1 
ATOM   3539 O  O   . GLY A  1 444 ? 21.88527 -2.93136  -30.76040 1.000 23.13831 ? 443 GLY A O   1 
ATOM   3540 N  N   . GLU A  1 445 ? 20.97036 -3.83791  -32.60756 1.000 25.74610 ? 444 GLU A N   1 
ATOM   3541 C  CA  . GLU A  1 445 ? 22.23087 -3.90599  -33.32834 1.000 26.48605 ? 444 GLU A CA  1 
ATOM   3542 C  C   . GLU A  1 445 ? 22.60072 -2.54482  -33.89485 1.000 23.50606 ? 444 GLU A C   1 
ATOM   3543 O  O   . GLU A  1 445 ? 21.74519 -1.80232  -34.38536 1.000 19.88552 ? 444 GLU A O   1 
ATOM   3544 C  CB  . GLU A  1 445 ? 22.15023 -4.93484  -34.45568 1.000 33.32054 ? 444 GLU A CB  1 
ATOM   3545 C  CG  . GLU A  1 445 ? 22.02759 -6.35353  -33.95479 1.000 30.16190 ? 444 GLU A CG  1 
ATOM   3546 C  CD  . GLU A  1 445 ? 23.03571 -6.65458  -32.86622 1.000 41.16773 ? 444 GLU A CD  1 
ATOM   3547 O  OE1 . GLU A  1 445 ? 24.25057 -6.64697  -33.15867 1.000 36.86937 ? 444 GLU A OE1 1 
ATOM   3548 O  OE2 . GLU A  1 445 ? 22.61289 -6.87853  -31.71149 1.000 42.96134 ? 444 GLU A OE2 1 
ATOM   3549 N  N   . LEU A  1 446 ? 23.88853 -2.22524  -33.82512 1.000 21.93776 ? 445 LEU A N   1 
ATOM   3550 C  CA  . LEU A  1 446 ? 24.41880 -0.96702  -34.33798 1.000 17.70876 ? 445 LEU A CA  1 
ATOM   3551 C  C   . LEU A  1 446 ? 25.09382 -1.27081  -35.67100 1.000 23.27386 ? 445 LEU A C   1 
ATOM   3552 O  O   . LEU A  1 446 ? 26.27361 -1.61949  -35.72856 1.000 26.90694 ? 445 LEU A O   1 
ATOM   3553 C  CB  . LEU A  1 446 ? 25.38185 -0.33688  -33.34024 1.000 19.90159 ? 445 LEU A CB  1 
ATOM   3554 C  CG  . LEU A  1 446 ? 25.44517 1.18820   -33.38419 1.000 24.51688 ? 445 LEU A CG  1 
ATOM   3555 C  CD1 . LEU A  1 446 ? 24.10542 1.75980   -32.96077 1.000 22.57923 ? 445 LEU A CD1 1 
ATOM   3556 C  CD2 . LEU A  1 446 ? 26.55546 1.70940   -32.49241 1.000 26.20916 ? 445 LEU A CD2 1 
ATOM   3557 N  N   . VAL A  1 447 ? 24.32624 -1.15121  -36.74942 1.000 21.09353 ? 446 VAL A N   1 
ATOM   3558 C  CA  . VAL A  1 447 ? 24.82462 -1.34243  -38.10589 1.000 17.04212 ? 446 VAL A CA  1 
ATOM   3559 C  C   . VAL A  1 447 ? 24.98427 0.02966   -38.74369 1.000 14.08933 ? 446 VAL A C   1 
ATOM   3560 O  O   . VAL A  1 447 ? 24.00941 0.77962   -38.87216 1.000 12.66762 ? 446 VAL A O   1 
ATOM   3561 C  CB  . VAL A  1 447 ? 23.88032 -2.22888  -38.93245 1.000 28.63149 ? 446 VAL A CB  1 
ATOM   3562 C  CG1 . VAL A  1 447 ? 24.35520 -2.30672  -40.37719 1.000 16.83713 ? 446 VAL A CG1 1 
ATOM   3563 C  CG2 . VAL A  1 447 ? 23.78200 -3.61681  -38.31865 1.000 23.80894 ? 446 VAL A CG2 1 
ATOM   3564 N  N   . PHE A  1 448 ? 26.20897 0.36363   -39.13735 1.000 13.68653 ? 447 PHE A N   1 
ATOM   3565 C  CA  . PHE A  1 448 ? 26.47479 1.65996   -39.73782 1.000 14.95855 ? 447 PHE A CA  1 
ATOM   3566 C  C   . PHE A  1 448 ? 26.05341 1.66984   -41.20239 1.000 15.68241 ? 447 PHE A C   1 
ATOM   3567 O  O   . PHE A  1 448 ? 26.07265 0.64266   -41.88759 1.000 16.41297 ? 447 PHE A O   1 
ATOM   3568 C  CB  . PHE A  1 448 ? 27.95347 2.01727   -39.60080 1.000 13.30795 ? 447 PHE A CB  1 
ATOM   3569 C  CG  . PHE A  1 448 ? 28.40653 2.16529   -38.17501 1.000 15.94223 ? 447 PHE A CG  1 
ATOM   3570 C  CD1 . PHE A  1 448 ? 28.04400 3.27782   -37.43311 1.000 12.91589 ? 447 PHE A CD1 1 
ATOM   3571 C  CD2 . PHE A  1 448 ? 29.19234 1.19359   -37.57648 1.000 17.33581 ? 447 PHE A CD2 1 
ATOM   3572 C  CE1 . PHE A  1 448 ? 28.45745 3.41981   -36.12318 1.000 17.47414 ? 447 PHE A CE1 1 
ATOM   3573 C  CE2 . PHE A  1 448 ? 29.60913 1.32981   -36.26587 1.000 14.11205 ? 447 PHE A CE2 1 
ATOM   3574 C  CZ  . PHE A  1 448 ? 29.24082 2.44413   -35.53861 1.000 16.93790 ? 447 PHE A CZ  1 
ATOM   3575 N  N   . THR A  1 449 ? 25.65364 2.85314   -41.67715 1.000 15.30663 ? 448 THR A N   1 
ATOM   3576 C  CA  . THR A  1 449 ? 25.11034 3.00215   -43.02233 1.000 14.39122 ? 448 THR A CA  1 
ATOM   3577 C  C   . THR A  1 449 ? 25.84164 4.06998   -43.82954 1.000 15.58223 ? 448 THR A C   1 
ATOM   3578 O  O   . THR A  1 449 ? 25.33899 4.49829   -44.87299 1.000 13.03151 ? 448 THR A O   1 
ATOM   3579 C  CB  . THR A  1 449 ? 23.61465 3.32394   -42.96649 1.000 12.28026 ? 448 THR A CB  1 
ATOM   3580 O  OG1 . THR A  1 449 ? 23.40678 4.49232   -42.16135 1.000 12.81888 ? 448 THR A OG1 1 
ATOM   3581 C  CG2 . THR A  1 449 ? 22.83690 2.15703   -42.36942 1.000 11.99217 ? 448 THR A CG2 1 
ATOM   3582 N  N   . GLY A  1 450 ? 27.01294 4.51099   -43.37521 1.000 13.40179 ? 449 GLY A N   1 
ATOM   3583 C  CA  . GLY A  1 450 ? 27.74407 5.54969   -44.05826 1.000 15.81202 ? 449 GLY A CA  1 
ATOM   3584 C  C   . GLY A  1 450 ? 29.11714 5.78978   -43.46692 1.000 16.26061 ? 449 GLY A C   1 
ATOM   3585 O  O   . GLY A  1 450 ? 29.46999 5.25862   -42.40868 1.000 15.21586 ? 449 GLY A O   1 
ATOM   3586 N  N   . PRO A  1 451 ? 29.91864 6.60809   -44.14426 1.000 16.87613 ? 450 PRO A N   1 
ATOM   3587 C  CA  . PRO A  1 451 ? 31.28484 6.85207   -43.67641 1.000 13.38060 ? 450 PRO A CA  1 
ATOM   3588 C  C   . PRO A  1 451 ? 31.30787 7.72968   -42.43718 1.000 15.61475 ? 450 PRO A C   1 
ATOM   3589 O  O   . PRO A  1 451 ? 30.39244 8.51640   -42.18060 1.000 19.72398 ? 450 PRO A O   1 
ATOM   3590 C  CB  . PRO A  1 451 ? 31.94340 7.55592   -44.86730 1.000 14.91851 ? 450 PRO A CB  1 
ATOM   3591 C  CG  . PRO A  1 451 ? 30.81415 8.24914   -45.54879 1.000 11.63484 ? 450 PRO A CG  1 
ATOM   3592 C  CD  . PRO A  1 451 ? 29.61537 7.34827   -45.38235 1.000 13.73872 ? 450 PRO A CD  1 
ATOM   3593 N  N   . ALA A  1 452 ? 32.37451 7.57544   -41.65819 1.000 16.75079 ? 451 ALA A N   1 
ATOM   3594 C  CA  . ALA A  1 452 ? 32.57287 8.39615   -40.47333 1.000 14.15368 ? 451 ALA A CA  1 
ATOM   3595 C  C   . ALA A  1 452 ? 33.05312 9.78323   -40.87412 1.000 11.94207 ? 451 ALA A C   1 
ATOM   3596 O  O   . ALA A  1 452 ? 33.80397 9.94318   -41.83946 1.000 15.29681 ? 451 ALA A O   1 
ATOM   3597 C  CB  . ALA A  1 452 ? 33.57957 7.74316   -39.52583 1.000 14.50707 ? 451 ALA A CB  1 
ATOM   3598 N  N   . ALA A  1 453 ? 32.60526 10.79246  -40.12854 1.000 14.90877 ? 452 ALA A N   1 
ATOM   3599 C  CA  . ALA A  1 453 ? 32.95618 12.17397  -40.41206 1.000 14.13341 ? 452 ALA A CA  1 
ATOM   3600 C  C   . ALA A  1 453 ? 33.55795 12.80199  -39.16117 1.000 19.23798 ? 452 ALA A C   1 
ATOM   3601 O  O   . ALA A  1 453 ? 32.95300 12.72533  -38.07719 1.000 19.88457 ? 452 ALA A O   1 
ATOM   3602 C  CB  . ALA A  1 453 ? 31.73402 12.97566  -40.87787 1.000 10.76769 ? 452 ALA A CB  1 
ATOM   3603 N  N   . PRO A  1 454 ? 34.72799 13.42553  -39.25934 1.000 20.63933 ? 453 PRO A N   1 
ATOM   3604 C  CA  . PRO A  1 454 ? 35.30806 14.10219  -38.09783 1.000 25.81652 ? 453 PRO A CA  1 
ATOM   3605 C  C   . PRO A  1 454 ? 34.51166 15.34643  -37.75465 1.000 26.86779 ? 453 PRO A C   1 
ATOM   3606 O  O   . PRO A  1 454 ? 33.75974 15.86059  -38.59697 1.000 28.56355 ? 453 PRO A O   1 
ATOM   3607 C  CB  . PRO A  1 454 ? 36.72397 14.45971  -38.57214 1.000 20.52617 ? 453 PRO A CB  1 
ATOM   3608 C  CG  . PRO A  1 454 ? 36.57765 14.61427  -40.04563 1.000 23.27901 ? 453 PRO A CG  1 
ATOM   3609 C  CD  . PRO A  1 454 ? 35.56063 13.58473  -40.46464 1.000 16.51950 ? 453 PRO A CD  1 
ATOM   3610 N  N   . PRO A  1 455 ? 34.63676 15.85733  -36.53283 1.000 23.88300 ? 454 PRO A N   1 
ATOM   3611 C  CA  . PRO A  1 455 ? 33.97264 17.11977  -36.19825 1.000 17.81606 ? 454 PRO A CA  1 
ATOM   3612 C  C   . PRO A  1 455 ? 34.55053 18.26818  -37.00966 1.000 20.90760 ? 454 PRO A C   1 
ATOM   3613 O  O   . PRO A  1 455 ? 35.66196 18.19668  -37.53864 1.000 24.32531 ? 454 PRO A O   1 
ATOM   3614 C  CB  . PRO A  1 455 ? 34.26431 17.29336  -34.70372 1.000 18.86644 ? 454 PRO A CB  1 
ATOM   3615 C  CG  . PRO A  1 455 ? 35.51267 16.50184  -34.47266 1.000 18.86961 ? 454 PRO A CG  1 
ATOM   3616 C  CD  . PRO A  1 455 ? 35.40956 15.32176  -35.39809 1.000 18.57928 ? 454 PRO A CD  1 
ATOM   3617 N  N   . ALA A  1 456 ? 33.76685 19.33889  -37.10970 1.000 24.13221 ? 455 ALA A N   1 
ATOM   3618 C  CA  . ALA A  1 456 ? 34.24039 20.54008  -37.77593 1.000 16.73263 ? 455 ALA A CA  1 
ATOM   3619 C  C   . ALA A  1 456 ? 35.49987 21.05545  -37.08829 1.000 19.46508 ? 455 ALA A C   1 
ATOM   3620 O  O   . ALA A  1 456 ? 35.74680 20.79151  -35.90758 1.000 20.08417 ? 455 ALA A O   1 
ATOM   3621 C  CB  . ALA A  1 456 ? 33.15646 21.61538  -37.77921 1.000 16.17127 ? 455 ALA A CB  1 
ATOM   3622 N  N   . GLN A  1 457 ? 36.30829 21.79615  -37.85004 1.000 23.21330 ? 456 GLN A N   1 
ATOM   3623 C  CA  . GLN A  1 457 ? 37.61015 22.22620  -37.34908 1.000 19.90168 ? 456 GLN A CA  1 
ATOM   3624 C  C   . GLN A  1 457 ? 37.48038 23.07756  -36.09191 1.000 22.53136 ? 456 GLN A C   1 
ATOM   3625 O  O   . GLN A  1 457 ? 38.34052 23.00903  -35.20599 1.000 20.69360 ? 456 GLN A O   1 
ATOM   3626 C  CB  . GLN A  1 457 ? 38.36493 22.98992  -38.43738 1.000 26.17592 ? 456 GLN A CB  1 
ATOM   3627 C  CG  . GLN A  1 457 ? 39.85402 22.69159  -38.47565 1.000 36.54682 ? 456 GLN A CG  1 
ATOM   3628 C  CD  . GLN A  1 457 ? 40.14975 21.26049  -38.88826 1.000 40.78215 ? 456 GLN A CD  1 
ATOM   3629 O  OE1 . GLN A  1 457 ? 40.92619 20.55985  -38.23638 1.000 35.26613 ? 456 GLN A OE1 1 
ATOM   3630 N  NE2 . GLN A  1 457 ? 39.53419 20.82141  -39.98087 1.000 44.59550 ? 456 GLN A NE2 1 
ATOM   3631 N  N   . ASN A  1 458 ? 36.41140 23.86616  -35.98184 1.000 20.40851 ? 457 ASN A N   1 
ATOM   3632 C  CA  . ASN A  1 458 ? 36.20722 24.69499  -34.80008 1.000 20.98335 ? 457 ASN A CA  1 
ATOM   3633 C  C   . ASN A  1 458 ? 35.63584 23.91827  -33.61999 1.000 17.08634 ? 457 ASN A C   1 
ATOM   3634 O  O   . ASN A  1 458 ? 35.32077 24.52861  -32.59273 1.000 13.66181 ? 457 ASN A O   1 
ATOM   3635 C  CB  . ASN A  1 458 ? 35.29280 25.87888  -35.13100 1.000 20.33961 ? 457 ASN A CB  1 
ATOM   3636 C  CG  . ASN A  1 458 ? 33.84316 25.47211  -35.28775 1.000 20.71426 ? 457 ASN A CG  1 
ATOM   3637 O  OD1 . ASN A  1 458 ? 33.53924 24.38626  -35.78182 1.000 27.49299 ? 457 ASN A OD1 1 
ATOM   3638 N  ND2 . ASN A  1 458 ? 32.93676 26.34523  -34.86483 1.000 19.49161 ? 457 ASN A ND2 1 
ATOM   3639 N  N   . GLU A  1 459 ? 35.48226 22.59841  -33.74184 1.000 16.00860 ? 458 GLU A N   1 
ATOM   3640 C  CA  . GLU A  1 459 ? 35.09166 21.74888  -32.62244 1.000 15.69526 ? 458 GLU A CA  1 
ATOM   3641 C  C   . GLU A  1 459 ? 36.12586 20.66042  -32.35472 1.000 14.38559 ? 458 GLU A C   1 
ATOM   3642 O  O   . GLU A  1 459 ? 35.80479 19.63625  -31.74410 1.000 14.87757 ? 458 GLU A O   1 
ATOM   3643 C  CB  . GLU A  1 459 ? 33.70996 21.13656  -32.86375 1.000 13.53601 ? 458 GLU A CB  1 
ATOM   3644 C  CG  . GLU A  1 459 ? 32.58601 22.16574  -32.88015 1.000 16.31379 ? 458 GLU A CG  1 
ATOM   3645 C  CD  . GLU A  1 459 ? 31.20533 21.54338  -32.79567 1.000 13.26936 ? 458 GLU A CD  1 
ATOM   3646 O  OE1 . GLU A  1 459 ? 31.10847 20.32179  -32.55192 1.000 14.87943 ? 458 GLU A OE1 1 
ATOM   3647 O  OE2 . GLU A  1 459 ? 30.21370 22.28108  -32.97266 1.000 15.14280 ? 458 GLU A OE2 1 
ATOM   3648 N  N   . LYS A  1 460 ? 37.36464 20.86696  -32.80317 1.000 14.51498 ? 459 LYS A N   1 
ATOM   3649 C  CA  . LYS A  1 460 ? 38.45486 19.93231  -32.56151 1.000 18.27196 ? 459 LYS A CA  1 
ATOM   3650 C  C   . LYS A  1 460 ? 39.09234 20.10240  -31.18843 1.000 19.86261 ? 459 LYS A C   1 
ATOM   3651 O  O   . LYS A  1 460 ? 39.94174 19.28667  -30.81438 1.000 23.40817 ? 459 LYS A O   1 
ATOM   3652 C  CB  . LYS A  1 460 ? 39.53093 20.09378  -33.64045 1.000 23.43482 ? 459 LYS A CB  1 
ATOM   3653 C  CG  . LYS A  1 460 ? 39.21240 19.43445  -34.97422 1.000 18.31954 ? 459 LYS A CG  1 
ATOM   3654 C  CD  . LYS A  1 460 ? 39.68345 17.98709  -34.99876 1.000 37.40666 ? 459 LYS A CD  1 
ATOM   3655 C  CE  . LYS A  1 460 ? 39.60285 17.39224  -36.39979 1.000 49.29893 ? 459 LYS A CE  1 
ATOM   3656 N  NZ  . LYS A  1 460 ? 40.95059 17.15007  -36.99203 1.000 48.50070 ? 459 LYS A NZ  1 
ATOM   3657 N  N   . GLY A  1 461 ? 38.70951 21.12949  -30.43250 1.000 14.02915 ? 460 GLY A N   1 
ATOM   3658 C  CA  . GLY A  1 461 ? 39.31795 21.41308  -29.15131 1.000 13.86067 ? 460 GLY A CA  1 
ATOM   3659 C  C   . GLY A  1 461 ? 38.58830 20.76053  -27.99257 1.000 12.97186 ? 460 GLY A C   1 
ATOM   3660 O  O   . GLY A  1 461 ? 37.67920 19.94554  -28.16016 1.000 12.88844 ? 460 GLY A O   1 
ATOM   3661 N  N   . LEU A  1 462 ? 39.01043 21.13708  -26.78815 1.000 12.57861 ? 461 LEU A N   1 
ATOM   3662 C  CA  . LEU A  1 462 ? 38.41834 20.59535  -25.57318 1.000 10.31433 ? 461 LEU A CA  1 
ATOM   3663 C  C   . LEU A  1 462 ? 36.98570 21.08933  -25.41323 1.000 10.39724 ? 461 LEU A C   1 
ATOM   3664 O  O   . LEU A  1 462 ? 36.72104 22.29393  -25.47232 1.000 9.72649  ? 461 LEU A O   1 
ATOM   3665 C  CB  . LEU A  1 462 ? 39.25506 20.99619  -24.36034 1.000 11.65220 ? 461 LEU A CB  1 
ATOM   3666 C  CG  . LEU A  1 462 ? 40.70885 20.52449  -24.34735 1.000 13.93889 ? 461 LEU A CG  1 
ATOM   3667 C  CD1 . LEU A  1 462 ? 41.48523 21.20322  -23.22936 1.000 19.67168 ? 461 LEU A CD1 1 
ATOM   3668 C  CD2 . LEU A  1 462 ? 40.77085 19.01318  -24.20019 1.000 17.70478 ? 461 LEU A CD2 1 
ATOM   3669 N  N   . LYS A  1 463 ? 36.05885 20.15595  -25.20895 1.000 11.29630 ? 462 LYS A N   1 
ATOM   3670 C  CA  . LYS A  1 463 ? 34.64992 20.48544  -25.05696 1.000 10.28404 ? 462 LYS A CA  1 
ATOM   3671 C  C   . LYS A  1 463 ? 34.03527 19.61061  -23.97437 1.000 10.48807 ? 462 LYS A C   1 
ATOM   3672 O  O   . LYS A  1 463 ? 34.51147 18.50525  -23.70189 1.000 12.37978 ? 462 LYS A O   1 
ATOM   3673 C  CB  . LYS A  1 463 ? 33.88586 20.30981  -26.37905 1.000 10.80097 ? 462 LYS A CB  1 
ATOM   3674 C  CG  . LYS A  1 463 ? 34.32487 21.27142  -27.47910 1.000 14.17844 ? 462 LYS A CG  1 
ATOM   3675 C  CD  . LYS A  1 463 ? 33.55125 21.05756  -28.76901 1.000 11.90889 ? 462 LYS A CD  1 
ATOM   3676 C  CE  . LYS A  1 463 ? 32.05973 21.23578  -28.55296 1.000 12.80333 ? 462 LYS A CE  1 
ATOM   3677 N  NZ  . LYS A  1 463 ? 31.73972 22.52611  -27.88410 1.000 13.39349 ? 462 LYS A NZ  1 
ATOM   3678 N  N   . ASP A  1 464 ? 32.97811 20.12580  -23.34580 1.000 9.24946  ? 463 ASP A N   1 
ATOM   3679 C  CA  . ASP A  1 464 ? 32.20018 19.35827  -22.38319 1.000 12.15775 ? 463 ASP A CA  1 
ATOM   3680 C  C   . ASP A  1 464 ? 30.76022 19.14325  -22.82891 1.000 12.69761 ? 463 ASP A C   1 
ATOM   3681 O  O   . ASP A  1 464 ? 30.00533 18.45885  -22.12846 1.000 11.57654 ? 463 ASP A O   1 
ATOM   3682 C  CB  . ASP A  1 464 ? 32.22185 20.03206  -21.00034 1.000 9.69566  ? 463 ASP A CB  1 
ATOM   3683 C  CG  . ASP A  1 464 ? 31.72578 21.46940  -21.03291 1.000 12.54230 ? 463 ASP A CG  1 
ATOM   3684 O  OD1 . ASP A  1 464 ? 30.55944 21.69928  -21.41845 1.000 12.54471 ? 463 ASP A OD1 1 
ATOM   3685 O  OD2 . ASP A  1 464 ? 32.50105 22.37228  -20.65287 1.000 13.83059 ? 463 ASP A OD2 1 
ATOM   3686 N  N   . THR A  1 465 ? 30.36017 19.70541  -23.96780 1.000 11.45876 ? 464 THR A N   1 
ATOM   3687 C  CA  . THR A  1 465 ? 29.02294 19.52679  -24.51547 1.000 8.35427  ? 464 THR A CA  1 
ATOM   3688 C  C   . THR A  1 465 ? 29.14654 19.32983  -26.01736 1.000 10.15298 ? 464 THR A C   1 
ATOM   3689 O  O   . THR A  1 465 ? 29.78901 20.13587  -26.69572 1.000 12.21113 ? 464 THR A O   1 
ATOM   3690 C  CB  . THR A  1 465 ? 28.12845 20.73305  -24.20634 1.000 11.30593 ? 464 THR A CB  1 
ATOM   3691 O  OG1 . THR A  1 465 ? 28.15121 20.99628  -22.79711 1.000 15.91454 ? 464 THR A OG1 1 
ATOM   3692 C  CG2 . THR A  1 465 ? 26.69617 20.46249  -24.64353 1.000 7.96087  ? 464 THR A CG2 1 
ATOM   3693 N  N   . VAL A  1 466 ? 28.53772 18.26493  -26.53465 1.000 10.15624 ? 465 VAL A N   1 
ATOM   3694 C  CA  . VAL A  1 466 ? 28.67605 17.88933  -27.93647 1.000 9.78060  ? 465 VAL A CA  1 
ATOM   3695 C  C   . VAL A  1 466 ? 27.29514 17.70717  -28.55308 1.000 10.91444 ? 465 VAL A C   1 
ATOM   3696 O  O   . VAL A  1 466 ? 26.40284 17.10503  -27.94500 1.000 10.23638 ? 465 VAL A O   1 
ATOM   3697 C  CB  . VAL A  1 466 ? 29.52432 16.60705  -28.09645 1.000 8.56986  ? 465 VAL A CB  1 
ATOM   3698 C  CG1 . VAL A  1 466 ? 28.99904 15.49727  -27.19776 1.000 9.54064  ? 465 VAL A CG1 1 
ATOM   3699 C  CG2 . VAL A  1 466 ? 29.55459 16.15559  -29.55138 1.000 8.50807  ? 465 VAL A CG2 1 
ATOM   3700 N  N   . LYS A  1 467 ? 27.12029 18.23948  -29.76121 1.000 11.90138 ? 466 LYS A N   1 
ATOM   3701 C  CA  . LYS A  1 467 ? 25.90061 18.03347  -30.53467 1.000 10.87060 ? 466 LYS A CA  1 
ATOM   3702 C  C   . LYS A  1 467 ? 25.94594 16.64441  -31.15899 1.000 12.95576 ? 466 LYS A C   1 
ATOM   3703 O  O   . LYS A  1 467 ? 26.79184 16.36921  -32.01648 1.000 15.57032 ? 466 LYS A O   1 
ATOM   3704 C  CB  . LYS A  1 467 ? 25.75992 19.10989  -31.60757 1.000 9.60709  ? 466 LYS A CB  1 
ATOM   3705 C  CG  . LYS A  1 467 ? 25.58653 20.51472  -31.06297 1.000 9.09977  ? 466 LYS A CG  1 
ATOM   3706 C  CD  . LYS A  1 467 ? 25.44525 21.53406  -32.18128 1.000 11.69240 ? 466 LYS A CD  1 
ATOM   3707 C  CE  . LYS A  1 467 ? 26.76038 21.74030  -32.91663 1.000 12.39262 ? 466 LYS A CE  1 
ATOM   3708 N  NZ  . LYS A  1 467 ? 27.78845 22.38280  -32.05154 1.000 11.62737 ? 466 LYS A NZ  1 
ATOM   3709 N  N   . VAL A  1 468 ? 25.04188 15.76714  -30.73298 1.000 12.81739 ? 467 VAL A N   1 
ATOM   3710 C  CA  . VAL A  1 468 ? 24.94912 14.40992  -31.26288 1.000 11.96622 ? 467 VAL A CA  1 
ATOM   3711 C  C   . VAL A  1 468 ? 23.88690 14.41325  -32.36055 1.000 11.58280 ? 467 VAL A C   1 
ATOM   3712 O  O   . VAL A  1 468 ? 22.69476 14.57762  -32.05195 1.000 11.11642 ? 467 VAL A O   1 
ATOM   3713 C  CB  . VAL A  1 468 ? 24.61395 13.39527  -30.16332 1.000 11.37761 ? 467 VAL A CB  1 
ATOM   3714 C  CG1 . VAL A  1 468 ? 24.59222 11.98918  -30.73324 1.000 9.94260  ? 467 VAL A CG1 1 
ATOM   3715 C  CG2 . VAL A  1 468 ? 25.62636 13.49440  -29.03319 1.000 12.14994 ? 467 VAL A CG2 1 
ATOM   3716 N  N   . PRO A  1 469 ? 24.25815 14.23896  -33.62568 1.000 11.40758 ? 468 PRO A N   1 
ATOM   3717 C  CA  . PRO A  1 469 ? 23.28802 14.37072  -34.72113 1.000 14.75266 ? 468 PRO A CA  1 
ATOM   3718 C  C   . PRO A  1 469 ? 22.24211 13.27227  -34.67062 1.000 14.17098 ? 468 PRO A C   1 
ATOM   3719 O  O   . PRO A  1 469 ? 22.48210 12.19514  -34.10397 1.000 13.52779 ? 468 PRO A O   1 
ATOM   3720 C  CB  . PRO A  1 469 ? 24.15998 14.24983  -35.98225 1.000 16.43286 ? 468 PRO A CB  1 
ATOM   3721 C  CG  . PRO A  1 469 ? 25.55842 14.52339  -35.52001 1.000 11.11333 ? 468 PRO A CG  1 
ATOM   3722 C  CD  . PRO A  1 469 ? 25.62211 14.00021  -34.12220 1.000 13.40848 ? 468 PRO A CD  1 
ATOM   3723 N  N   . PRO A  1 470 ? 21.06700 13.50535  -35.25333 1.000 15.16952 ? 469 PRO A N   1 
ATOM   3724 C  CA  . PRO A  1 470 ? 20.03404 12.46388  -35.26309 1.000 13.68768 ? 469 PRO A CA  1 
ATOM   3725 C  C   . PRO A  1 470 ? 20.39117 11.33947  -36.22188 1.000 11.31293 ? 469 PRO A C   1 
ATOM   3726 O  O   . PRO A  1 470 ? 20.90255 11.57065  -37.31967 1.000 15.06012 ? 469 PRO A O   1 
ATOM   3727 C  CB  . PRO A  1 470 ? 18.77898 13.21492  -35.72069 1.000 17.01603 ? 469 PRO A CB  1 
ATOM   3728 C  CG  . PRO A  1 470 ? 19.30358 14.34941  -36.53152 1.000 13.17079 ? 469 PRO A CG  1 
ATOM   3729 C  CD  . PRO A  1 470 ? 20.60595 14.75131  -35.89054 1.000 17.05859 ? 469 PRO A CD  1 
ATOM   3730 N  N   . GLY A  1 471 ? 20.11573 10.11037  -35.79260 1.000 13.60554 ? 470 GLY A N   1 
ATOM   3731 C  CA  . GLY A  1 471 ? 20.43951 8.95320   -36.60025 1.000 9.78754  ? 470 GLY A CA  1 
ATOM   3732 C  C   . GLY A  1 471 ? 21.91702 8.68504   -36.75497 1.000 14.86814 ? 470 GLY A C   1 
ATOM   3733 O  O   . GLY A  1 471 ? 22.31394 7.97837   -37.68541 1.000 15.14249 ? 470 GLY A O   1 
ATOM   3734 N  N   . SER A  1 472 ? 22.74727 9.22928   -35.86813 1.000 13.99843 ? 471 SER A N   1 
ATOM   3735 C  CA  . SER A  1 472 ? 24.18912 9.06209   -35.94129 1.000 12.92087 ? 471 SER A CA  1 
ATOM   3736 C  C   . SER A  1 472 ? 24.73633 8.69968   -34.56844 1.000 15.86310 ? 471 SER A C   1 
ATOM   3737 O  O   . SER A  1 472 ? 24.08709 8.90749   -33.54006 1.000 12.50171 ? 471 SER A O   1 
ATOM   3738 C  CB  . SER A  1 472 ? 24.87903 10.33322  -36.45486 1.000 11.37535 ? 471 SER A CB  1 
ATOM   3739 O  OG  . SER A  1 472 ? 24.33764 10.74057  -37.69724 1.000 23.35117 ? 471 SER A OG  1 
ATOM   3740 N  N   . VAL A  1 473 ? 25.94934 8.15324   -34.56871 1.000 13.96290 ? 472 VAL A N   1 
ATOM   3741 C  CA  . VAL A  1 473 ? 26.68363 7.83299   -33.35135 1.000 8.79076  ? 472 VAL A CA  1 
ATOM   3742 C  C   . VAL A  1 473 ? 27.82887 8.82540   -33.21733 1.000 12.46180 ? 472 VAL A C   1 
ATOM   3743 O  O   . VAL A  1 473 ? 28.62237 8.99565   -34.15080 1.000 17.29643 ? 472 VAL A O   1 
ATOM   3744 C  CB  . VAL A  1 473 ? 27.20792 6.38682   -33.36938 1.000 11.77142 ? 472 VAL A CB  1 
ATOM   3745 C  CG1 . VAL A  1 473 ? 27.99884 6.09171   -32.10295 1.000 11.90383 ? 472 VAL A CG1 1 
ATOM   3746 C  CG2 . VAL A  1 473 ? 26.05605 5.40697   -33.52339 1.000 16.55498 ? 472 VAL A CG2 1 
ATOM   3747 N  N   . THR A  1 474 ? 27.91074 9.48358   -32.06473 1.000 12.24091 ? 473 THR A N   1 
ATOM   3748 C  CA  . THR A  1 474 ? 28.96989 10.44171  -31.77352 1.000 11.71579 ? 473 THR A CA  1 
ATOM   3749 C  C   . THR A  1 474 ? 29.94335 9.81461   -30.78591 1.000 15.21949 ? 473 THR A C   1 
ATOM   3750 O  O   . THR A  1 474 ? 29.54321 9.39833   -29.69288 1.000 18.20344 ? 473 THR A O   1 
ATOM   3751 C  CB  . THR A  1 474 ? 28.40205 11.74471  -31.20990 1.000 14.90011 ? 473 THR A CB  1 
ATOM   3752 O  OG1 . THR A  1 474 ? 27.79852 12.50337  -32.26497 1.000 11.21261 ? 473 THR A OG1 1 
ATOM   3753 C  CG2 . THR A  1 474 ? 29.50518 12.57212  -30.56315 1.000 14.63767 ? 473 THR A CG2 1 
ATOM   3754 N  N   . ARG A  1 475 ? 31.21337 9.74946   -31.17229 1.000 16.18056 ? 474 ARG A N   1 
ATOM   3755 C  CA  . ARG A  1 475 ? 32.26779 9.20191   -30.33086 1.000 13.73356 ? 474 ARG A CA  1 
ATOM   3756 C  C   . ARG A  1 475 ? 33.04931 10.33506  -29.68236 1.000 10.63253 ? 474 ARG A C   1 
ATOM   3757 O  O   . ARG A  1 475 ? 33.44139 11.29229  -30.35673 1.000 12.95255 ? 474 ARG A O   1 
ATOM   3758 C  CB  . ARG A  1 475 ? 33.20736 8.31174   -31.14509 1.000 14.72080 ? 474 ARG A CB  1 
ATOM   3759 C  CG  . ARG A  1 475 ? 32.81344 6.84712   -31.15905 1.000 16.88782 ? 474 ARG A CG  1 
ATOM   3760 C  CD  . ARG A  1 475 ? 33.11539 6.20709   -32.50008 1.000 19.40897 ? 474 ARG A CD  1 
ATOM   3761 N  NE  . ARG A  1 475 ? 34.44040 6.55660   -32.99707 1.000 24.37874 ? 474 ARG A NE  1 
ATOM   3762 C  CZ  . ARG A  1 475 ? 35.54906 5.88981   -32.70790 1.000 27.16372 ? 474 ARG A CZ  1 
ATOM   3763 N  NH1 . ARG A  1 475 ? 35.53367 4.83773   -31.90623 1.000 26.63461 ? 474 ARG A NH1 1 
ATOM   3764 N  NH2 . ARG A  1 475 ? 36.70232 6.29004   -33.23482 1.000 29.02093 ? 474 ARG A NH2 1 
ATOM   3765 N  N   . ILE A  1 476 ? 33.26216 10.22783  -28.37458 1.000 12.15658 ? 475 ILE A N   1 
ATOM   3766 C  CA  . ILE A  1 476 ? 34.09411 11.16231  -27.63087 1.000 12.65578 ? 475 ILE A CA  1 
ATOM   3767 C  C   . ILE A  1 476 ? 35.08609 10.35618  -26.80659 1.000 12.22386 ? 475 ILE A C   1 
ATOM   3768 O  O   . ILE A  1 476 ? 34.78941 9.24338   -26.36124 1.000 14.69499 ? 475 ILE A O   1 
ATOM   3769 C  CB  . ILE A  1 476 ? 33.26343 12.09828  -26.72024 1.000 10.27800 ? 475 ILE A CB  1 
ATOM   3770 C  CG1 . ILE A  1 476 ? 32.54690 11.29655  -25.63005 1.000 11.46032 ? 475 ILE A CG1 1 
ATOM   3771 C  CG2 . ILE A  1 476 ? 32.25925 12.89368  -27.53669 1.000 6.87743  ? 475 ILE A CG2 1 
ATOM   3772 C  CD1 . ILE A  1 476 ? 31.83348 12.15399  -24.60717 1.000 9.49031  ? 475 ILE A CD1 1 
ATOM   3773 N  N   . ILE A  1 477 ? 36.27795 10.91562  -26.61590 1.000 13.21441 ? 476 ILE A N   1 
ATOM   3774 C  CA  . ILE A  1 477 ? 37.29365 10.32313  -25.75412 1.000 10.86744 ? 476 ILE A CA  1 
ATOM   3775 C  C   . ILE A  1 477 ? 37.45071 11.21350  -24.52909 1.000 12.51085 ? 476 ILE A C   1 
ATOM   3776 O  O   . ILE A  1 477 ? 37.48583 12.44480  -24.64126 1.000 10.64306 ? 476 ILE A O   1 
ATOM   3777 C  CB  . ILE A  1 477 ? 38.63683 10.11867  -26.48828 1.000 13.74242 ? 476 ILE A CB  1 
ATOM   3778 C  CG1 . ILE A  1 477 ? 39.53734 9.17171   -25.69414 1.000 16.39672 ? 476 ILE A CG1 1 
ATOM   3779 C  CG2 . ILE A  1 477 ? 39.35577 11.44244  -26.74529 1.000 15.43110 ? 476 ILE A CG2 1 
ATOM   3780 C  CD1 . ILE A  1 477 ? 40.94926 9.08326   -26.23427 1.000 23.84549 ? 476 ILE A CD1 1 
ATOM   3781 N  N   . ALA A  1 478 ? 37.51197 10.59137  -23.35412 1.000 12.11701 ? 477 ALA A N   1 
ATOM   3782 C  CA  . ALA A  1 478 ? 37.51800 11.32966  -22.10089 1.000 10.78586 ? 477 ALA A CA  1 
ATOM   3783 C  C   . ALA A  1 478 ? 38.42066 10.63915  -21.09224 1.000 14.73105 ? 477 ALA A C   1 
ATOM   3784 O  O   . ALA A  1 478 ? 38.44142 9.40865   -21.00442 1.000 14.21016 ? 477 ALA A O   1 
ATOM   3785 C  CB  . ALA A  1 478 ? 36.10165 11.46199  -21.52552 1.000 8.26278  ? 477 ALA A CB  1 
ATOM   3786 N  N   . THR A  1 479 ? 39.16355 11.44140  -20.33381 1.000 11.73277 ? 478 THR A N   1 
ATOM   3787 C  CA  . THR A  1 479 ? 40.00156 10.95971  -19.24179 1.000 12.37559 ? 478 THR A CA  1 
ATOM   3788 C  C   . THR A  1 479 ? 39.40024 11.47208  -17.93942 1.000 14.83409 ? 478 THR A C   1 
ATOM   3789 O  O   . THR A  1 479 ? 39.40968 12.67932  -17.67707 1.000 16.97573 ? 478 THR A O   1 
ATOM   3790 C  CB  . THR A  1 479 ? 41.44569 11.42662  -19.40318 1.000 14.56865 ? 478 THR A CB  1 
ATOM   3791 O  OG1 . THR A  1 479 ? 41.93272 11.03916  -20.69345 1.000 15.25720 ? 478 THR A OG1 1 
ATOM   3792 C  CG2 . THR A  1 479 ? 42.32465 10.80383  -18.32880 1.000 14.19045 ? 478 THR A CG2 1 
ATOM   3793 N  N   . PHE A  1 480 ? 38.87861 10.55736  -17.12789 1.000 17.54282 ? 479 PHE A N   1 
ATOM   3794 C  CA  . PHE A  1 480 ? 38.15016 10.92656  -15.91677 1.000 14.31155 ? 479 PHE A CA  1 
ATOM   3795 C  C   . PHE A  1 480 ? 39.15164 11.18594  -14.80075 1.000 14.28444 ? 479 PHE A C   1 
ATOM   3796 O  O   . PHE A  1 480 ? 39.62662 10.26032  -14.13871 1.000 19.30602 ? 479 PHE A O   1 
ATOM   3797 C  CB  . PHE A  1 480 ? 37.14329 9.84216   -15.55795 1.000 11.58899 ? 479 PHE A CB  1 
ATOM   3798 C  CG  . PHE A  1 480 ? 36.05039 9.69637   -16.57324 1.000 12.52315 ? 479 PHE A CG  1 
ATOM   3799 C  CD1 . PHE A  1 480 ? 36.21162 8.86736   -17.66944 1.000 12.89178 ? 479 PHE A CD1 1 
ATOM   3800 C  CD2 . PHE A  1 480 ? 34.87633 10.41983  -16.45300 1.000 15.86319 ? 479 PHE A CD2 1 
ATOM   3801 C  CE1 . PHE A  1 480 ? 35.21289 8.74484   -18.61428 1.000 16.18285 ? 479 PHE A CE1 1 
ATOM   3802 C  CE2 . PHE A  1 480 ? 33.87388 10.30146  -17.39492 1.000 12.15710 ? 479 PHE A CE2 1 
ATOM   3803 C  CZ  . PHE A  1 480 ? 34.04243 9.46314   -18.47648 1.000 10.82612 ? 479 PHE A CZ  1 
ATOM   3804 N  N   . ALA A  1 481 ? 39.46534 12.46057  -14.59425 1.000 15.36781 ? 480 ALA A N   1 
ATOM   3805 C  CA  . ALA A  1 481 ? 40.50275 12.89029  -13.66956 1.000 17.68048 ? 480 ALA A CA  1 
ATOM   3806 C  C   . ALA A  1 481 ? 40.25996 14.35666  -13.33839 1.000 18.40698 ? 480 ALA A C   1 
ATOM   3807 O  O   . ALA A  1 481 ? 39.54452 15.04845  -14.07360 1.000 13.28433 ? 480 ALA A O   1 
ATOM   3808 C  CB  . ALA A  1 481 ? 41.90167 12.68873  -14.27840 1.000 11.88115 ? 480 ALA A CB  1 
ATOM   3809 N  N   . PRO A  1 482 ? 40.83631 14.86526  -12.23547 1.000 20.66796 ? 481 PRO A N   1 
ATOM   3810 C  CA  . PRO A  1 482 ? 41.67304 14.19328  -11.23617 1.000 15.10218 ? 481 PRO A CA  1 
ATOM   3811 C  C   . PRO A  1 482 ? 40.91037 13.86653  -9.95932  1.000 15.66055 ? 481 PRO A C   1 
ATOM   3812 O  O   . PRO A  1 482 ? 41.48957 13.37095  -8.99662  1.000 15.55644 ? 481 PRO A O   1 
ATOM   3813 C  CB  . PRO A  1 482 ? 42.77063 15.22935  -10.99264 1.000 9.05039  ? 481 PRO A CB  1 
ATOM   3814 C  CG  . PRO A  1 482 ? 42.00956 16.53555  -11.04555 1.000 18.42100 ? 481 PRO A CG  1 
ATOM   3815 C  CD  . PRO A  1 482 ? 40.87741 16.32658  -12.04591 1.000 17.96292 ? 481 PRO A CD  1 
ATOM   3816 N  N   . TYR A  1 483 ? 39.61060 14.13994  -9.91759  1.000 12.52705 ? 482 TYR A N   1 
ATOM   3817 C  CA  . TYR A  1 483 ? 38.79803 13.90510  -8.73449  1.000 17.48327 ? 482 TYR A CA  1 
ATOM   3818 C  C   . TYR A  1 483 ? 37.91686 12.68225  -8.94179  1.000 19.13186 ? 482 TYR A C   1 
ATOM   3819 O  O   . TYR A  1 483 ? 37.44880 12.42099  -10.05445 1.000 20.99097 ? 482 TYR A O   1 
ATOM   3820 C  CB  . TYR A  1 483 ? 37.92514 15.12063  -8.40957  1.000 17.16495 ? 482 TYR A CB  1 
ATOM   3821 C  CG  . TYR A  1 483 ? 38.67679 16.43023  -8.39647  1.000 20.46229 ? 482 TYR A CG  1 
ATOM   3822 C  CD1 . TYR A  1 483 ? 39.70585 16.65419  -7.49072  1.000 17.60939 ? 482 TYR A CD1 1 
ATOM   3823 C  CD2 . TYR A  1 483 ? 38.35126 17.44757  -9.28432  1.000 18.23725 ? 482 TYR A CD2 1 
ATOM   3824 C  CE1 . TYR A  1 483 ? 40.39639 17.85240  -7.47627  1.000 15.65062 ? 482 TYR A CE1 1 
ATOM   3825 C  CE2 . TYR A  1 483 ? 39.03483 18.64878  -9.27579  1.000 19.44785 ? 482 TYR A CE2 1 
ATOM   3826 C  CZ  . TYR A  1 483 ? 40.05519 18.84537  -8.37011  1.000 17.12766 ? 482 TYR A CZ  1 
ATOM   3827 O  OH  . TYR A  1 483 ? 40.73681 20.03955  -8.36019  1.000 20.38344 ? 482 TYR A OH  1 
ATOM   3828 N  N   . SER A  1 484 ? 37.70058 11.93574  -7.86608  1.000 17.18973 ? 483 SER A N   1 
ATOM   3829 C  CA  . SER A  1 484 ? 36.79187 10.80254  -7.85693  1.000 22.37725 ? 483 SER A CA  1 
ATOM   3830 C  C   . SER A  1 484 ? 35.55425 11.14806  -7.03978  1.000 19.96090 ? 483 SER A C   1 
ATOM   3831 O  O   . SER A  1 484 ? 35.57181 12.04618  -6.19359  1.000 19.28584 ? 483 SER A O   1 
ATOM   3832 C  CB  . SER A  1 484 ? 37.47352 9.55557   -7.28291  1.000 19.85101 ? 483 SER A CB  1 
ATOM   3833 O  OG  . SER A  1 484 ? 37.89846 9.77887   -5.94951  1.000 20.04729 ? 483 SER A OG  1 
ATOM   3834 N  N   . GLY A  1 485 ? 34.46779 10.42724  -7.30694  1.000 17.21838 ? 484 GLY A N   1 
ATOM   3835 C  CA  . GLY A  1 485 ? 33.24329 10.63352  -6.57137  1.000 14.20027 ? 484 GLY A CA  1 
ATOM   3836 C  C   . GLY A  1 485 ? 32.05112 10.68384  -7.49807  1.000 16.97985 ? 484 GLY A C   1 
ATOM   3837 O  O   . GLY A  1 485 ? 32.08199 10.15813  -8.61639  1.000 21.92218 ? 484 GLY A O   1 
ATOM   3838 N  N   . ARG A  1 486 ? 30.99495 11.33918  -7.02639  1.000 16.10901 ? 485 ARG A N   1 
ATOM   3839 C  CA  . ARG A  1 486 ? 29.69358 11.31798  -7.67972  1.000 18.96056 ? 485 ARG A CA  1 
ATOM   3840 C  C   . ARG A  1 486 ? 29.51074 12.56971  -8.53081  1.000 18.40884 ? 485 ARG A C   1 
ATOM   3841 O  O   . ARG A  1 486 ? 29.49260 13.68834  -8.00578  1.000 21.33271 ? 485 ARG A O   1 
ATOM   3842 C  CB  . ARG A  1 486 ? 28.57894 11.20603  -6.63963  1.000 18.95791 ? 485 ARG A CB  1 
ATOM   3843 C  CG  . ARG A  1 486 ? 27.17920 11.25550  -7.21807  1.000 20.82711 ? 485 ARG A CG  1 
ATOM   3844 C  CD  . ARG A  1 486 ? 26.93715 10.13191  -8.21533  1.000 18.63526 ? 485 ARG A CD  1 
ATOM   3845 N  NE  . ARG A  1 486 ? 26.93997 8.82203   -7.57593  1.000 28.65774 ? 485 ARG A NE  1 
ATOM   3846 C  CZ  . ARG A  1 486 ? 25.88175 8.27044   -6.99726  1.000 34.75417 ? 485 ARG A CZ  1 
ATOM   3847 N  NH1 . ARG A  1 486 ? 24.71588 8.89498   -6.94918  1.000 23.87500 ? 485 ARG A NH1 1 
ATOM   3848 N  NH2 . ARG A  1 486 ? 25.99573 7.06229   -6.45229  1.000 31.15736 ? 485 ARG A NH2 1 
ATOM   3849 N  N   . TYR A  1 487 ? 29.37815 12.37383  -9.84184  1.000 16.52469 ? 486 TYR A N   1 
ATOM   3850 C  CA  . TYR A  1 487 ? 29.01197 13.44002  -10.76628 1.000 15.11480 ? 486 TYR A CA  1 
ATOM   3851 C  C   . TYR A  1 487 ? 27.78110 13.01384  -11.55435 1.000 13.70489 ? 486 TYR A C   1 
ATOM   3852 O  O   . TYR A  1 487 ? 27.15697 11.99789  -11.23227 1.000 15.58276 ? 486 TYR A O   1 
ATOM   3853 C  CB  . TYR A  1 487 ? 30.16386 13.76449  -11.71939 1.000 12.29309 ? 486 TYR A CB  1 
ATOM   3854 C  CG  . TYR A  1 487 ? 31.40112 14.30923  -11.04755 1.000 16.16085 ? 486 TYR A CG  1 
ATOM   3855 C  CD1 . TYR A  1 487 ? 32.36937 13.45584  -10.53356 1.000 19.42163 ? 486 TYR A CD1 1 
ATOM   3856 C  CD2 . TYR A  1 487 ? 31.60958 15.67823  -10.93944 1.000 19.10534 ? 486 TYR A CD2 1 
ATOM   3857 C  CE1 . TYR A  1 487 ? 33.50724 13.95077  -9.92246  1.000 19.07998 ? 486 TYR A CE1 1 
ATOM   3858 C  CE2 . TYR A  1 487 ? 32.74511 16.18254  -10.33006 1.000 19.31070 ? 486 TYR A CE2 1 
ATOM   3859 C  CZ  . TYR A  1 487 ? 33.68901 15.31437  -9.82308  1.000 16.33503 ? 486 TYR A CZ  1 
ATOM   3860 O  OH  . TYR A  1 487 ? 34.81812 15.81132  -9.21573  1.000 18.67775 ? 486 TYR A OH  1 
ATOM   3861 N  N   . VAL A  1 488 ? 27.42320 13.77340  -12.59089 1.000 14.76613 ? 487 VAL A N   1 
ATOM   3862 C  CA  . VAL A  1 488 ? 26.31517 13.42064  -13.46944 1.000 15.32305 ? 487 VAL A CA  1 
ATOM   3863 C  C   . VAL A  1 488 ? 26.69257 13.74463  -14.90752 1.000 14.49725 ? 487 VAL A C   1 
ATOM   3864 O  O   . VAL A  1 488 ? 27.59892 14.53451  -15.17905 1.000 14.17851 ? 487 VAL A O   1 
ATOM   3865 C  CB  . VAL A  1 488 ? 24.99734 14.14722  -13.10609 1.000 10.09850 ? 487 VAL A CB  1 
ATOM   3866 C  CG1 . VAL A  1 488 ? 24.50172 13.72590  -11.73436 1.000 14.08269 ? 487 VAL A CG1 1 
ATOM   3867 C  CG2 . VAL A  1 488 ? 25.18225 15.64719  -13.17210 1.000 7.27584  ? 487 VAL A CG2 1 
ATOM   3868 N  N   . TRP A  1 489 ? 25.97975 13.10859  -15.83194 1.000 14.31634 ? 488 TRP A N   1 
ATOM   3869 C  CA  . TRP A  1 489 ? 26.02667 13.45087  -17.24362 1.000 10.97993 ? 488 TRP A CA  1 
ATOM   3870 C  C   . TRP A  1 489 ? 24.59973 13.43269  -17.76798 1.000 14.26658 ? 488 TRP A C   1 
ATOM   3871 O  O   . TRP A  1 489 ? 23.75809 12.67342  -17.27871 1.000 15.77602 ? 488 TRP A O   1 
ATOM   3872 C  CB  . TRP A  1 489 ? 26.91214 12.48372  -18.03921 1.000 11.22802 ? 488 TRP A CB  1 
ATOM   3873 C  CG  . TRP A  1 489 ? 26.29094 11.14218  -18.24024 1.000 13.22531 ? 488 TRP A CG  1 
ATOM   3874 C  CD1 . TRP A  1 489 ? 26.13388 10.16283  -17.30440 1.000 15.22711 ? 488 TRP A CD1 1 
ATOM   3875 C  CD2 . TRP A  1 489 ? 25.74006 10.62738  -19.45723 1.000 12.10488 ? 488 TRP A CD2 1 
ATOM   3876 N  NE1 . TRP A  1 489 ? 25.51696 9.06954   -17.86259 1.000 13.57241 ? 488 TRP A NE1 1 
ATOM   3877 C  CE2 . TRP A  1 489 ? 25.26452 9.32964   -19.18376 1.000 11.17657 ? 488 TRP A CE2 1 
ATOM   3878 C  CE3 . TRP A  1 489 ? 25.60172 11.13857  -20.75146 1.000 12.33757 ? 488 TRP A CE3 1 
ATOM   3879 C  CZ2 . TRP A  1 489 ? 24.66252 8.53557   -20.15568 1.000 10.50992 ? 488 TRP A CZ2 1 
ATOM   3880 C  CZ3 . TRP A  1 489 ? 25.00317 10.34919  -21.71529 1.000 12.96388 ? 488 TRP A CZ3 1 
ATOM   3881 C  CH2 . TRP A  1 489 ? 24.54256 9.06026   -21.41280 1.000 12.30449 ? 488 TRP A CH2 1 
ATOM   3882 N  N   . HIS A  1 490 ? 24.32543 14.27824  -18.75678 1.000 12.72248 ? 489 HIS A N   1 
ATOM   3883 C  CA  . HIS A  1 490 ? 22.95063 14.45923  -19.20496 1.000 12.95156 ? 489 HIS A CA  1 
ATOM   3884 C  C   . HIS A  1 490 ? 22.94168 15.23875  -20.51020 1.000 11.89707 ? 489 HIS A C   1 
ATOM   3885 O  O   . HIS A  1 490 ? 23.96408 15.76902  -20.95204 1.000 11.04318 ? 489 HIS A O   1 
ATOM   3886 C  CB  . HIS A  1 490 ? 22.12061 15.19281  -18.15081 1.000 14.15813 ? 489 HIS A CB  1 
ATOM   3887 C  CG  . HIS A  1 490 ? 22.67098 16.53451  -17.78273 1.000 13.93972 ? 489 HIS A CG  1 
ATOM   3888 N  ND1 . HIS A  1 490 ? 22.32186 17.69053  -18.44690 1.000 10.90975 ? 489 HIS A ND1 1 
ATOM   3889 C  CD2 . HIS A  1 490 ? 23.55975 16.90150  -16.82958 1.000 12.39925 ? 489 HIS A CD2 1 
ATOM   3890 C  CE1 . HIS A  1 490 ? 22.96491 18.71328  -17.91248 1.000 12.16004 ? 489 HIS A CE1 1 
ATOM   3891 N  NE2 . HIS A  1 490 ? 23.72257 18.26138  -16.92937 1.000 13.87549 ? 489 HIS A NE2 1 
ATOM   3892 N  N   . CYS A  1 491 ? 21.76128 15.29742  -21.11972 1.000 11.05260 ? 490 CYS A N   1 
ATOM   3893 C  CA  . CYS A  1 491 ? 21.50581 16.22915  -22.20532 1.000 15.37245 ? 490 CYS A CA  1 
ATOM   3894 C  C   . CYS A  1 491 ? 21.20668 17.60557  -21.62849 1.000 15.32125 ? 490 CYS A C   1 
ATOM   3895 O  O   . CYS A  1 491 ? 20.49506 17.73224  -20.62771 1.000 14.78925 ? 490 CYS A O   1 
ATOM   3896 C  CB  . CYS A  1 491 ? 20.33310 15.74748  -23.05821 1.000 11.75941 ? 490 CYS A CB  1 
ATOM   3897 S  SG  . CYS A  1 491 ? 19.75981 16.94499  -24.27742 1.000 19.57279 ? 490 CYS A SG  1 
ATOM   3898 N  N   . HIS A  1 492 ? 21.75563 18.64070  -22.25782 1.000 14.61267 ? 491 HIS A N   1 
ATOM   3899 C  CA  . HIS A  1 492 ? 21.63487 19.98904  -21.72421 1.000 13.80036 ? 491 HIS A CA  1 
ATOM   3900 C  C   . HIS A  1 492 ? 20.41216 20.73328  -22.24686 1.000 14.79261 ? 491 HIS A C   1 
ATOM   3901 O  O   . HIS A  1 492 ? 20.30383 21.94563  -22.03424 1.000 13.76805 ? 491 HIS A O   1 
ATOM   3902 C  CB  . HIS A  1 492 ? 22.90094 20.79509  -22.01192 1.000 11.66276 ? 491 HIS A CB  1 
ATOM   3903 C  CG  . HIS A  1 492 ? 23.25696 21.75220  -20.91769 1.000 13.97032 ? 491 HIS A CG  1 
ATOM   3904 N  ND1 . HIS A  1 492 ? 22.57398 22.93110  -20.70809 1.000 15.54656 ? 491 HIS A ND1 1 
ATOM   3905 C  CD2 . HIS A  1 492 ? 24.21338 21.69663  -19.96105 1.000 11.94819 ? 491 HIS A CD2 1 
ATOM   3906 C  CE1 . HIS A  1 492 ? 23.10011 23.56476  -19.67529 1.000 11.50028 ? 491 HIS A CE1 1 
ATOM   3907 N  NE2 . HIS A  1 492 ? 24.09806 22.83816  -19.20560 1.000 13.05774 ? 491 HIS A NE2 1 
ATOM   3908 N  N   . ILE A  1 493 ? 19.49938 20.04772  -22.92883 1.000 14.14889 ? 492 ILE A N   1 
ATOM   3909 C  CA  . ILE A  1 493 ? 18.16163 20.58492  -23.15081 1.000 16.05724 ? 492 ILE A CA  1 
ATOM   3910 C  C   . ILE A  1 493 ? 17.39083 20.37517  -21.85279 1.000 16.70355 ? 492 ILE A C   1 
ATOM   3911 O  O   . ILE A  1 493 ? 17.02284 19.24783  -21.51568 1.000 18.84882 ? 492 ILE A O   1 
ATOM   3912 C  CB  . ILE A  1 493 ? 17.45930 19.91155  -24.33396 1.000 16.76872 ? 492 ILE A CB  1 
ATOM   3913 C  CG1 . ILE A  1 493 ? 18.21810 20.18366  -25.63139 1.000 15.40510 ? 492 ILE A CG1 1 
ATOM   3914 C  CG2 . ILE A  1 493 ? 16.02513 20.40777  -24.44920 1.000 13.23340 ? 492 ILE A CG2 1 
ATOM   3915 C  CD1 . ILE A  1 493 ? 17.61161 19.50842  -26.84340 1.000 18.00916 ? 492 ILE A CD1 1 
ATOM   3916 N  N   . LEU A  1 494 ? 17.16071 21.46185  -21.11328 1.000 15.03310 ? 493 LEU A N   1 
ATOM   3917 C  CA  . LEU A  1 494 ? 16.66442 21.33509  -19.74669 1.000 17.34243 ? 493 LEU A CA  1 
ATOM   3918 C  C   . LEU A  1 494 ? 15.30017 20.66212  -19.69242 1.000 19.49601 ? 493 LEU A C   1 
ATOM   3919 O  O   . LEU A  1 494 ? 14.98829 19.97623  -18.71159 1.000 19.70433 ? 493 LEU A O   1 
ATOM   3920 C  CB  . LEU A  1 494 ? 16.61318 22.70907  -19.08552 1.000 16.42275 ? 493 LEU A CB  1 
ATOM   3921 C  CG  . LEU A  1 494 ? 17.93535 23.47527  -19.12888 1.000 14.01627 ? 493 LEU A CG  1 
ATOM   3922 C  CD1 . LEU A  1 494 ? 17.83165 24.74956  -18.32158 1.000 12.95302 ? 493 LEU A CD1 1 
ATOM   3923 C  CD2 . LEU A  1 494 ? 19.08865 22.61107  -18.63826 1.000 10.79543 ? 493 LEU A CD2 1 
ATOM   3924 N  N   . GLU A  1 495 ? 14.47765 20.83855  -20.72916 1.000 17.77443 ? 494 GLU A N   1 
ATOM   3925 C  CA  . GLU A  1 495 ? 13.20663 20.12546  -20.78222 1.000 18.26993 ? 494 GLU A CA  1 
ATOM   3926 C  C   . GLU A  1 495 ? 13.41691 18.62195  -20.91604 1.000 21.98012 ? 494 GLU A C   1 
ATOM   3927 O  O   . GLU A  1 495 ? 12.56309 17.83813  -20.48507 1.000 24.90097 ? 494 GLU A O   1 
ATOM   3928 C  CB  . GLU A  1 495 ? 12.35074 20.65507  -21.93354 1.000 20.36821 ? 494 GLU A CB  1 
ATOM   3929 C  CG  . GLU A  1 495 ? 11.67127 21.99142  -21.65091 1.000 20.44217 ? 494 GLU A CG  1 
ATOM   3930 C  CD  . GLU A  1 495 ? 12.64729 23.15196  -21.56480 1.000 27.55999 ? 494 GLU A CD  1 
ATOM   3931 O  OE1 . GLU A  1 495 ? 13.76156 23.04189  -22.12121 1.000 26.10059 ? 494 GLU A OE1 1 
ATOM   3932 O  OE2 . GLU A  1 495 ? 12.29961 24.17572  -20.93742 1.000 26.71316 ? 494 GLU A OE2 1 
ATOM   3933 N  N   . HIS A  1 496 ? 14.54140 18.20306  -21.50533 1.000 19.51883 ? 495 HIS A N   1 
ATOM   3934 C  CA  . HIS A  1 496 ? 14.88823 16.78583  -21.54757 1.000 17.43837 ? 495 HIS A CA  1 
ATOM   3935 C  C   . HIS A  1 496 ? 15.55083 16.33610  -20.25211 1.000 15.71582 ? 495 HIS A C   1 
ATOM   3936 O  O   . HIS A  1 496 ? 15.25341 15.24913  -19.74414 1.000 16.79797 ? 495 HIS A O   1 
ATOM   3937 C  CB  . HIS A  1 496 ? 15.82087 16.49851  -22.72599 1.000 21.49413 ? 495 HIS A CB  1 
ATOM   3938 C  CG  . HIS A  1 496 ? 15.19801 16.72390  -24.06742 1.000 19.70127 ? 495 HIS A CG  1 
ATOM   3939 N  ND1 . HIS A  1 496 ? 15.91829 16.65720  -25.24054 1.000 16.46006 ? 495 HIS A ND1 1 
ATOM   3940 C  CD2 . HIS A  1 496 ? 13.92425 17.01011  -24.42398 1.000 21.76786 ? 495 HIS A CD2 1 
ATOM   3941 C  CE1 . HIS A  1 496 ? 15.11574 16.89606  -26.26205 1.000 18.77333 ? 495 HIS A CE1 1 
ATOM   3942 N  NE2 . HIS A  1 496 ? 13.89985 17.11258  -25.79392 1.000 22.85261 ? 495 HIS A NE2 1 
ATOM   3943 N  N   . GLU A  1 497 ? 16.45427 17.16007  -19.71379 1.000 18.12000 ? 496 GLU A N   1 
ATOM   3944 C  CA  . GLU A  1 497 ? 17.20712 16.78051  -18.52207 1.000 14.60161 ? 496 GLU A CA  1 
ATOM   3945 C  C   . GLU A  1 497 ? 16.28743 16.51893  -17.33689 1.000 15.42881 ? 496 GLU A C   1 
ATOM   3946 O  O   . GLU A  1 497 ? 16.46247 15.53210  -16.61281 1.000 21.43892 ? 496 GLU A O   1 
ATOM   3947 C  CB  . GLU A  1 497 ? 18.22019 17.87282  -18.18031 1.000 15.41694 ? 496 GLU A CB  1 
ATOM   3948 C  CG  . GLU A  1 497 ? 18.83182 17.74750  -16.79647 1.000 14.32706 ? 496 GLU A CG  1 
ATOM   3949 C  CD  . GLU A  1 497 ? 19.72024 18.92401  -16.44625 1.000 18.47250 ? 496 GLU A CD  1 
ATOM   3950 O  OE1 . GLU A  1 497 ? 20.07756 19.69484  -17.36254 1.000 16.38319 ? 496 GLU A OE1 1 
ATOM   3951 O  OE2 . GLU A  1 497 ? 20.05752 19.08154  -15.25370 1.000 21.85755 ? 496 GLU A OE2 1 
ATOM   3952 N  N   . ASP A  1 498 ? 15.29765 17.38833  -17.12467 1.000 16.48039 ? 497 ASP A N   1 
ATOM   3953 C  CA  . ASP A  1 498 ? 14.42152 17.24788  -15.96842 1.000 15.73913 ? 497 ASP A CA  1 
ATOM   3954 C  C   . ASP A  1 498 ? 13.50896 16.03271  -16.06240 1.000 18.34636 ? 497 ASP A C   1 
ATOM   3955 O  O   . ASP A  1 498 ? 12.97768 15.59772  -15.03566 1.000 24.42863 ? 497 ASP A O   1 
ATOM   3956 C  CB  . ASP A  1 498 ? 13.57912 18.51101  -15.78738 1.000 17.50873 ? 497 ASP A CB  1 
ATOM   3957 C  CG  . ASP A  1 498 ? 14.36591 19.65230  -15.17734 1.000 18.71237 ? 497 ASP A CG  1 
ATOM   3958 O  OD1 . ASP A  1 498 ? 15.33626 19.38010  -14.44018 1.000 15.87498 ? 497 ASP A OD1 1 
ATOM   3959 O  OD2 . ASP A  1 498 ? 14.01134 20.82155  -15.42892 1.000 18.95236 ? 497 ASP A OD2 1 
ATOM   3960 N  N   . TYR A  1 499 ? 13.31639 15.47173  -17.25584 1.000 18.95527 ? 498 TYR A N   1 
ATOM   3961 C  CA  . TYR A  1 499 ? 12.40306 14.34478  -17.40483 1.000 23.83134 ? 498 TYR A CA  1 
ATOM   3962 C  C   . TYR A  1 499 ? 12.65734 13.57518  -18.69634 1.000 19.24778 ? 498 TYR A C   1 
ATOM   3963 O  O   . TYR A  1 499 ? 11.98782 13.81771  -19.70577 1.000 17.46084 ? 498 TYR A O   1 
ATOM   3964 C  CB  . TYR A  1 499 ? 10.95529 14.83906  -17.35850 1.000 16.97641 ? 498 TYR A CB  1 
ATOM   3965 C  CG  . TYR A  1 499 ? 9.91756  13.74796  -17.24775 1.000 19.91659 ? 498 TYR A CG  1 
ATOM   3966 C  CD1 . TYR A  1 499 ? 9.94391  12.84164  -16.19582 1.000 21.94034 ? 498 TYR A CD1 1 
ATOM   3967 C  CD2 . TYR A  1 499 ? 8.89549  13.63927  -18.18145 1.000 24.79589 ? 498 TYR A CD2 1 
ATOM   3968 C  CE1 . TYR A  1 499 ? 8.99078  11.84678  -16.08514 1.000 22.07829 ? 498 TYR A CE1 1 
ATOM   3969 C  CE2 . TYR A  1 499 ? 7.93646  12.64925  -18.07858 1.000 28.90066 ? 498 TYR A CE2 1 
ATOM   3970 C  CZ  . TYR A  1 499 ? 7.98873  11.75593  -17.02805 1.000 25.43707 ? 498 TYR A CZ  1 
ATOM   3971 O  OH  . TYR A  1 499 ? 7.03580  10.76897  -16.92086 1.000 25.67412 ? 498 TYR A OH  1 
ATOM   3972 N  N   . ASP A  1 500 ? 13.61393 12.64916  -18.68547 1.000 16.69664 ? 499 ASP A N   1 
ATOM   3973 C  CA  . ASP A  1 500 ? 14.46355 12.37737  -17.52841 1.000 17.64731 ? 499 ASP A CA  1 
ATOM   3974 C  C   . ASP A  1 500 ? 15.86626 12.04032  -18.02559 1.000 17.29619 ? 499 ASP A C   1 
ATOM   3975 O  O   . ASP A  1 500 ? 16.50304 11.09800  -17.55277 1.000 16.34788 ? 499 ASP A O   1 
ATOM   3976 C  CB  . ASP A  1 500 ? 13.90105 11.22722  -16.68558 1.000 20.11282 ? 499 ASP A CB  1 
ATOM   3977 C  CG  . ASP A  1 500 ? 14.60652 11.08285  -15.34767 1.000 25.61805 ? 499 ASP A CG  1 
ATOM   3978 O  OD1 . ASP A  1 500 ? 15.30440 12.03315  -14.93697 1.000 30.23138 ? 499 ASP A OD1 1 
ATOM   3979 O  OD2 . ASP A  1 500 ? 14.47673 10.01577  -14.71326 1.000 32.28655 ? 499 ASP A OD2 1 
ATOM   3980 N  N   . MET A  1 501 ? 16.34400 12.82255  -18.99089 1.000 14.14749 ? 500 MET A N   1 
ATOM   3981 C  CA  . MET A  1 501 ? 17.57771 12.49889  -19.69592 1.000 16.87387 ? 500 MET A CA  1 
ATOM   3982 C  C   . MET A  1 501 ? 18.80997 12.86483  -18.87593 1.000 18.54817 ? 500 MET A C   1 
ATOM   3983 O  O   . MET A  1 501 ? 19.70238 13.56275  -19.36754 1.000 17.85722 ? 500 MET A O   1 
ATOM   3984 C  CB  . MET A  1 501 ? 17.60194 13.20955  -21.05145 1.000 14.20890 ? 500 MET A CB  1 
ATOM   3985 C  CG  . MET A  1 501 ? 18.42897 12.50672  -22.11226 1.000 18.08758 ? 500 MET A CG  1 
ATOM   3986 S  SD  . MET A  1 501 ? 18.09047 13.11412  -23.77775 1.000 23.89326 ? 500 MET A SD  1 
ATOM   3987 C  CE  . MET A  1 501 ? 17.66004 11.58697  -24.60923 1.000 21.57118 ? 500 MET A CE  1 
ATOM   3988 N  N   . MET A  1 502 ? 18.87271 12.39486  -17.63029 1.000 14.83310 ? 501 MET A N   1 
ATOM   3989 C  CA  . MET A  1 502 ? 20.00880 12.65130  -16.75687 1.000 16.10391 ? 501 MET A CA  1 
ATOM   3990 C  C   . MET A  1 502 ? 20.35906 11.37890  -16.00160 1.000 15.18459 ? 501 MET A C   1 
ATOM   3991 O  O   . MET A  1 502 ? 19.46944 10.64522  -15.56237 1.000 18.52380 ? 501 MET A O   1 
ATOM   3992 C  CB  . MET A  1 502 ? 19.71705 13.78903  -15.76747 1.000 15.69631 ? 501 MET A CB  1 
ATOM   3993 C  CG  . MET A  1 502 ? 20.92701 14.20994  -14.94412 1.000 17.33846 ? 501 MET A CG  1 
ATOM   3994 S  SD  . MET A  1 502 ? 20.60938 15.61779  -13.86723 1.000 18.70987 ? 501 MET A SD  1 
ATOM   3995 C  CE  . MET A  1 502 ? 19.48973 14.88881  -12.67517 1.000 17.04806 ? 501 MET A CE  1 
ATOM   3996 N  N   . ARG A  1 503 ? 21.65503 11.12481  -15.84950 1.000 15.85914 ? 502 ARG A N   1 
ATOM   3997 C  CA  . ARG A  1 503 ? 22.14611 9.90633   -15.22549 1.000 16.48709 ? 502 ARG A CA  1 
ATOM   3998 C  C   . ARG A  1 503 ? 23.34234 10.22036  -14.33947 1.000 18.42499 ? 502 ARG A C   1 
ATOM   3999 O  O   . ARG A  1 503 ? 24.09908 11.15844  -14.61996 1.000 13.87128 ? 502 ARG A O   1 
ATOM   4000 C  CB  . ARG A  1 503 ? 22.54038 8.86332   -16.28316 1.000 12.41094 ? 502 ARG A CB  1 
ATOM   4001 C  CG  . ARG A  1 503 ? 21.35111 8.20428   -16.96537 1.000 18.89907 ? 502 ARG A CG  1 
ATOM   4002 C  CD  . ARG A  1 503 ? 20.66708 7.23479   -16.02046 1.000 14.11821 ? 502 ARG A CD  1 
ATOM   4003 N  NE  . ARG A  1 503 ? 21.54703 6.12245   -15.68540 1.000 11.61651 ? 502 ARG A NE  1 
ATOM   4004 C  CZ  . ARG A  1 503 ? 21.40408 5.34428   -14.62209 1.000 16.77064 ? 502 ARG A CZ  1 
ATOM   4005 N  NH1 . ARG A  1 503 ? 20.42591 5.53629   -13.75146 1.000 19.38447 ? 502 ARG A NH1 1 
ATOM   4006 N  NH2 . ARG A  1 503 ? 22.26681 4.35045   -14.42554 1.000 15.84619 ? 502 ARG A NH2 1 
ATOM   4007 N  N   . PRO A  1 504 ? 23.53414 9.45920   -13.26441 1.000 17.86885 ? 503 PRO A N   1 
ATOM   4008 C  CA  . PRO A  1 504 ? 24.68509 9.69078   -12.38661 1.000 14.96786 ? 503 PRO A CA  1 
ATOM   4009 C  C   . PRO A  1 504 ? 25.97877 9.16156   -12.98449 1.000 11.83076 ? 503 PRO A C   1 
ATOM   4010 O  O   . PRO A  1 504 ? 25.99622 8.18374   -13.73454 1.000 16.32200 ? 503 PRO A O   1 
ATOM   4011 C  CB  . PRO A  1 504 ? 24.31388 8.91891   -11.11493 1.000 15.88017 ? 503 PRO A CB  1 
ATOM   4012 C  CG  . PRO A  1 504 ? 23.43840 7.81520   -11.60666 1.000 15.91812 ? 503 PRO A CG  1 
ATOM   4013 C  CD  . PRO A  1 504 ? 22.64983 8.39782   -12.75010 1.000 15.80816 ? 503 PRO A CD  1 
ATOM   4014 N  N   . LEU A  1 505 ? 27.07711 9.82804   -12.63110 1.000 13.23494 ? 504 LEU A N   1 
ATOM   4015 C  CA  . LEU A  1 505 ? 28.41078 9.47728   -13.11328 1.000 15.75131 ? 504 LEU A CA  1 
ATOM   4016 C  C   . LEU A  1 505 ? 29.32692 9.31206   -11.90852 1.000 18.43288 ? 504 LEU A C   1 
ATOM   4017 O  O   . LEU A  1 505 ? 29.63058 10.28966  -11.21846 1.000 21.21685 ? 504 LEU A O   1 
ATOM   4018 C  CB  . LEU A  1 505 ? 28.95047 10.54394  -14.06909 1.000 16.39185 ? 504 LEU A CB  1 
ATOM   4019 C  CG  . LEU A  1 505 ? 30.35143 10.32190  -14.64521 1.000 15.63548 ? 504 LEU A CG  1 
ATOM   4020 C  CD1 . LEU A  1 505 ? 30.40935 9.02197   -15.42590 1.000 13.73930 ? 504 LEU A CD1 1 
ATOM   4021 C  CD2 . LEU A  1 505 ? 30.76831 11.49287  -15.52311 1.000 12.22012 ? 504 LEU A CD2 1 
ATOM   4022 N  N   . GLU A  1 506 ? 29.77192 8.08327   -11.65754 1.000 19.10070 ? 505 GLU A N   1 
ATOM   4023 C  CA  . GLU A  1 506 ? 30.58765 7.75988   -10.49081 1.000 18.63620 ? 505 GLU A CA  1 
ATOM   4024 C  C   . GLU A  1 506 ? 32.00885 7.45069   -10.94525 1.000 16.64840 ? 505 GLU A C   1 
ATOM   4025 O  O   . GLU A  1 506 ? 32.23954 6.46162   -11.64773 1.000 20.39819 ? 505 GLU A O   1 
ATOM   4026 C  CB  . GLU A  1 506 ? 29.99318 6.58100   -9.72401  1.000 18.04847 ? 505 GLU A CB  1 
ATOM   4027 C  CG  . GLU A  1 506 ? 30.78007 6.18019   -8.48348  1.000 21.46869 ? 505 GLU A CG  1 
ATOM   4028 C  CD  . GLU A  1 506 ? 30.68898 7.20845   -7.37071  1.000 20.61458 ? 505 GLU A CD  1 
ATOM   4029 O  OE1 . GLU A  1 506 ? 29.73970 8.01898   -7.38134  1.000 24.20237 ? 505 GLU A OE1 1 
ATOM   4030 O  OE2 . GLU A  1 506 ? 31.56677 7.20576   -6.48308  1.000 23.47525 ? 505 GLU A OE2 1 
ATOM   4031 N  N   . VAL A  1 507 ? 32.95610 8.29174   -10.54207 1.000 18.81764 ? 506 VAL A N   1 
ATOM   4032 C  CA  . VAL A  1 507 ? 34.37455 8.06924   -10.79937 1.000 19.81620 ? 506 VAL A CA  1 
ATOM   4033 C  C   . VAL A  1 507 ? 34.96944 7.41190   -9.56142  1.000 20.23931 ? 506 VAL A C   1 
ATOM   4034 O  O   . VAL A  1 507 ? 34.88721 7.96202   -8.45628  1.000 19.86176 ? 506 VAL A O   1 
ATOM   4035 C  CB  . VAL A  1 507 ? 35.09874 9.38070   -11.14113 1.000 18.21892 ? 506 VAL A CB  1 
ATOM   4036 C  CG1 . VAL A  1 507 ? 36.55694 9.10875   -11.48447 1.000 16.06873 ? 506 VAL A CG1 1 
ATOM   4037 C  CG2 . VAL A  1 507 ? 34.39822 10.08764  -12.29353 1.000 13.08448 ? 506 VAL A CG2 1 
ATOM   4038 N  N   . THR A  1 508 ? 35.56237 6.23494   -9.73976  1.000 20.79123 ? 507 THR A N   1 
ATOM   4039 C  CA  . THR A  1 508 ? 36.00314 5.39807   -8.63152  1.000 18.23667 ? 507 THR A CA  1 
ATOM   4040 C  C   . THR A  1 508 ? 37.52291 5.31150   -8.60250  1.000 20.91300 ? 507 THR A C   1 
ATOM   4041 O  O   . THR A  1 508 ? 38.15148 4.99656   -9.61799  1.000 22.44804 ? 507 THR A O   1 
ATOM   4042 C  CB  . THR A  1 508 ? 35.40498 3.99355   -8.74036  1.000 23.18620 ? 507 THR A CB  1 
ATOM   4043 O  OG1 . THR A  1 508 ? 33.98012 4.08516   -8.86999  1.000 19.74560 ? 507 THR A OG1 1 
ATOM   4044 C  CG2 . THR A  1 508 ? 35.74505 3.17432   -7.50610  1.000 17.50071 ? 507 THR A CG2 1 
ATOM   4045 N  N   . ASP A  1 509 ? 38.10515 5.58671   -7.43768  1.000 31.62629 ? 508 ASP A N   1 
ATOM   4046 C  CA  . ASP A  1 509 ? 39.53436 5.39934   -7.23336  1.000 29.95530 ? 508 ASP A CA  1 
ATOM   4047 C  C   . ASP A  1 509 ? 39.81862 3.94723   -6.87171  1.000 30.48754 ? 508 ASP A C   1 
ATOM   4048 O  O   . ASP A  1 509 ? 39.10296 3.33835   -6.07085  1.000 26.70371 ? 508 ASP A O   1 
ATOM   4049 C  CB  . ASP A  1 509 ? 40.04224 6.32830   -6.12761  1.000 39.24051 ? 508 ASP A CB  1 
ATOM   4050 C  CG  . ASP A  1 509 ? 41.56326 6.38592   -6.04921  1.000 41.41578 ? 508 ASP A CG  1 
ATOM   4051 O  OD1 . ASP A  1 509 ? 42.23771 5.42887   -6.48633  1.000 40.78094 ? 508 ASP A OD1 1 
ATOM   4052 O  OD2 . ASP A  1 509 ? 42.08663 7.39978   -5.53892  1.000 36.35893 ? 508 ASP A OD2 1 
ATOM   4053 N  N   . ILE A  1 510 ? 40.87565 3.39662   -7.46281  1.000 43.87724 ? 509 ILE A N   1 
ATOM   4054 C  CA  . ILE A  1 510 ? 41.27501 2.00967   -7.24910  1.000 39.61745 ? 509 ILE A CA  1 
ATOM   4055 C  C   . ILE A  1 510 ? 42.57610 2.00140   -6.45906  1.000 46.06584 ? 509 ILE A C   1 
ATOM   4056 O  O   . ILE A  1 510 ? 43.54494 2.66956   -6.84112  1.000 43.05184 ? 509 ILE A O   1 
ATOM   4057 C  CB  . ILE A  1 510 ? 41.43027 1.25451   -8.58204  1.000 35.20521 ? 509 ILE A CB  1 
ATOM   4058 C  CG1 . ILE A  1 510 ? 40.08939 1.17983   -9.32426  1.000 32.97511 ? 509 ILE A CG1 1 
ATOM   4059 C  CG2 . ILE A  1 510 ? 42.01896 -0.12986  -8.35301  1.000 53.23741 ? 509 ILE A CG2 1 
ATOM   4060 C  CD1 . ILE A  1 510 ? 38.88825 0.98396   -8.41278  1.000 31.06623 ? 509 ILE A CD1 1 
ATOM   4061 N  N   . ARG A  1 511 ? 42.60131 1.24437   -5.36047  1.000 57.62692 ? 510 ARG A N   1 
ATOM   4062 C  CA  . ARG A  1 511 ? 43.78278 1.22124   -4.50697  1.000 55.71873 ? 510 ARG A CA  1 
ATOM   4063 C  C   . ARG A  1 511 ? 44.11946 -0.17538  -3.99315  1.000 59.14541 ? 510 ARG A C   1 
ATOM   4064 O  O   . ARG A  1 511 ? 45.29162 -0.56458  -3.99765  1.000 64.41102 ? 510 ARG A O   1 
ATOM   4065 C  CB  . ARG A  1 511 ? 43.60579 2.18418   -3.32936  1.000 53.75512 ? 510 ARG A CB  1 
ATOM   4066 C  CG  . ARG A  1 511 ? 42.28393 2.05270   -2.58554  1.000 56.34982 ? 510 ARG A CG  1 
ATOM   4067 C  CD  . ARG A  1 511 ? 42.32494 2.82252   -1.27146  1.000 60.27955 ? 510 ARG A CD  1 
ATOM   4068 N  NE  . ARG A  1 511 ? 43.23005 2.20481   -0.30796  1.000 62.98631 ? 510 ARG A NE  1 
ATOM   4069 C  CZ  . ARG A  1 511 ? 42.83880 1.48070   0.73224   1.000 38.52004 ? 510 ARG A CZ  1 
ATOM   4070 N  NH1 . ARG A  1 511 ? 41.55744 1.29175   1.00050   1.000 48.35161 ? 510 ARG A NH1 1 
ATOM   4071 N  NH2 . ARG A  1 511 ? 43.75611 0.93340   1.52390   1.000 20.94959 ? 510 ARG A NH2 1 
ATOM   4072 N  N   . HIS A  1 512 ? 43.12245 -0.94178  -3.54757  1.000 48.72439 ? 511 HIS A N   1 
ATOM   4073 C  CA  . HIS A  1 512 ? 43.40985 -2.21347  -2.88653  1.000 55.36137 ? 511 HIS A CA  1 
ATOM   4074 C  C   . HIS A  1 512 ? 42.39080 -3.28232  -3.26503  1.000 60.96143 ? 511 HIS A C   1 
ATOM   4075 O  O   . HIS A  1 512 ? 42.01694 -4.12442  -2.44109  1.000 51.88021 ? 511 HIS A O   1 
ATOM   4076 C  CB  . HIS A  1 512 ? 43.46816 -2.04171  -1.36874  1.000 52.17149 ? 511 HIS A CB  1 
ATOM   4077 C  CG  . HIS A  1 512 ? 44.35311 -3.03653  -0.68386  1.000 43.87301 ? 511 HIS A CG  1 
ATOM   4078 N  ND1 . HIS A  1 512 ? 45.55918 -3.44481  -1.21203  1.000 46.66514 ? 511 HIS A ND1 1 
ATOM   4079 C  CD2 . HIS A  1 512 ? 44.21210 -3.70024  0.48796   1.000 42.43537 ? 511 HIS A CD2 1 
ATOM   4080 C  CE1 . HIS A  1 512 ? 46.12133 -4.31981  -0.39761  1.000 38.19656 ? 511 HIS A CE1 1 
ATOM   4081 N  NE2 . HIS A  1 512 ? 45.32458 -4.49205  0.64191   1.000 50.53005 ? 511 HIS A NE2 1 
ATOM   4082 N  N   . GLN A  1 513 ? 41.93991 -3.26996  -4.51747  1.000 67.12396 ? 512 GLN A N   1 
ATOM   4083 C  CA  . GLN A  1 513 ? 41.10279 -4.34042  -5.06289  1.000 58.61154 ? 512 GLN A CA  1 
ATOM   4084 C  C   . GLN A  1 513 ? 40.92628 -4.16873  -6.56700  1.000 54.45341 ? 512 GLN A C   1 
ATOM   4085 O  O   . GLN A  1 513 ? 41.87754 -3.84504  -7.27772  1.000 48.23673 ? 512 GLN A O   1 
ATOM   4086 C  CB  . GLN A  1 513 ? 39.73547 -4.38247  -4.37632  1.000 46.21741 ? 512 GLN A CB  1 
ATOM   4087 C  CG  . GLN A  1 513 ? 38.98645 -3.06725  -4.39339  1.000 62.27057 ? 512 GLN A CG  1 
ATOM   4088 C  CD  . GLN A  1 513 ? 38.30204 -2.78517  -3.07317  1.000 52.58636 ? 512 GLN A CD  1 
ATOM   4089 O  OE1 . GLN A  1 513 ? 38.65746 -3.36041  -2.04360  1.000 54.43654 ? 512 GLN A OE1 1 
ATOM   4090 N  NE2 . GLN A  1 513 ? 37.31379 -1.89843  -3.09448  1.000 39.66053 ? 512 GLN A NE2 1 
ATOM   4091 N  N   . LYS B  1 2   ? 40.06284 -17.23535 -51.21898 1.000 39.40739 ? 2   LYS B N   1 
ATOM   4092 C  CA  . LYS B  1 2   ? 41.32734 -17.30728 -51.94168 1.000 41.41359 ? 2   LYS B CA  1 
ATOM   4093 C  C   . LYS B  1 2   ? 41.89349 -15.91399 -52.20231 1.000 41.99346 ? 2   LYS B C   1 
ATOM   4094 O  O   . LYS B  1 2   ? 41.51865 -14.94966 -51.53272 1.000 42.19092 ? 2   LYS B O   1 
ATOM   4095 C  CB  . LYS B  1 2   ? 41.14960 -18.05785 -53.26368 1.000 40.18152 ? 2   LYS B CB  1 
ATOM   4096 C  CG  . LYS B  1 2   ? 40.13514 -17.43032 -54.20934 1.000 43.39617 ? 2   LYS B CG  1 
ATOM   4097 C  CD  . LYS B  1 2   ? 40.16654 -18.10615 -55.57128 1.000 45.03858 ? 2   LYS B CD  1 
ATOM   4098 C  CE  . LYS B  1 2   ? 39.09923 -17.54558 -56.50003 1.000 48.85253 ? 2   LYS B CE  1 
ATOM   4099 N  NZ  . LYS B  1 2   ? 39.33565 -16.11918 -56.85943 1.000 34.10129 ? 2   LYS B NZ  1 
ATOM   4100 N  N   . LEU B  1 3   ? 42.79751 -15.82665 -53.18150 1.000 43.62843 ? 3   LEU B N   1 
ATOM   4101 C  CA  . LEU B  1 3   ? 43.45242 -14.57794 -53.56067 1.000 31.64873 ? 3   LEU B CA  1 
ATOM   4102 C  C   . LEU B  1 3   ? 44.23817 -13.98822 -52.39716 1.000 31.60547 ? 3   LEU B C   1 
ATOM   4103 O  O   . LEU B  1 3   ? 43.73598 -13.12159 -51.67373 1.000 32.10858 ? 3   LEU B O   1 
ATOM   4104 C  CB  . LEU B  1 3   ? 42.43141 -13.56345 -54.08354 1.000 27.87436 ? 3   LEU B CB  1 
ATOM   4105 C  CG  . LEU B  1 3   ? 42.40662 -13.36683 -55.59951 1.000 28.16167 ? 3   LEU B CG  1 
ATOM   4106 C  CD1 . LEU B  1 3   ? 42.30095 -14.70672 -56.30284 1.000 31.28720 ? 3   LEU B CD1 1 
ATOM   4107 C  CD2 . LEU B  1 3   ? 41.26091 -12.45727 -56.00333 1.000 19.59724 ? 3   LEU B CD2 1 
ATOM   4108 N  N   . GLU B  1 4   ? 45.47155 -14.45309 -52.21413 1.000 30.43341 ? 4   GLU B N   1 
ATOM   4109 C  CA  . GLU B  1 4   ? 46.31821 -13.93776 -51.14809 1.000 27.54675 ? 4   GLU B CA  1 
ATOM   4110 C  C   . GLU B  1 4   ? 46.64241 -12.47106 -51.39905 1.000 27.38400 ? 4   GLU B C   1 
ATOM   4111 O  O   . GLU B  1 4   ? 47.00186 -12.08397 -52.51480 1.000 26.27419 ? 4   GLU B O   1 
ATOM   4112 C  CB  . GLU B  1 4   ? 47.60319 -14.75645 -51.04980 1.000 28.75200 ? 4   GLU B CB  1 
ATOM   4113 C  CG  . GLU B  1 4   ? 48.55623 -14.28406 -49.96825 1.000 28.15306 ? 4   GLU B CG  1 
ATOM   4114 C  CD  . GLU B  1 4   ? 49.83046 -15.10103 -49.92257 1.000 37.69372 ? 4   GLU B CD  1 
ATOM   4115 O  OE1 . GLU B  1 4   ? 49.98390 -16.01068 -50.76652 1.000 30.71957 ? 4   GLU B OE1 1 
ATOM   4116 O  OE2 . GLU B  1 4   ? 50.67851 -14.83473 -49.04359 1.000 36.98171 ? 4   GLU B OE2 1 
ATOM   4117 N  N   . LYS B  1 5   ? 46.51373 -11.65572 -50.35839 1.000 26.58528 ? 5   LYS B N   1 
ATOM   4118 C  CA  . LYS B  1 5   ? 46.74802 -10.22804 -50.49640 1.000 21.54184 ? 5   LYS B CA  1 
ATOM   4119 C  C   . LYS B  1 5   ? 48.23830 -9.92377  -50.59645 1.000 22.51822 ? 5   LYS B C   1 
ATOM   4120 O  O   . LYS B  1 5   ? 49.08266 -10.64287 -50.05503 1.000 30.37201 ? 5   LYS B O   1 
ATOM   4121 C  CB  . LYS B  1 5   ? 46.14729 -9.46993  -49.31107 1.000 23.06519 ? 5   LYS B CB  1 
ATOM   4122 C  CG  . LYS B  1 5   ? 44.63363 -9.55459  -49.20906 1.000 18.85434 ? 5   LYS B CG  1 
ATOM   4123 C  CD  . LYS B  1 5   ? 44.11126 -8.69801  -48.06486 1.000 23.72788 ? 5   LYS B CD  1 
ATOM   4124 C  CE  . LYS B  1 5   ? 44.46813 -9.28853  -46.71033 1.000 22.01659 ? 5   LYS B CE  1 
ATOM   4125 N  NZ  . LYS B  1 5   ? 43.77770 -10.58715 -46.48027 1.000 26.50014 ? 5   LYS B NZ  1 
ATOM   4126 N  N   . PHE B  1 6   ? 48.55136 -8.84501  -51.31933 1.000 21.09085 ? 6   PHE B N   1 
ATOM   4127 C  CA  . PHE B  1 6   ? 49.87578 -8.21796  -51.30098 1.000 21.14446 ? 6   PHE B CA  1 
ATOM   4128 C  C   . PHE B  1 6   ? 50.95014 -9.14599  -51.87203 1.000 24.64564 ? 6   PHE B C   1 
ATOM   4129 O  O   . PHE B  1 6   ? 52.03385 -9.29499  -51.30603 1.000 26.99973 ? 6   PHE B O   1 
ATOM   4130 C  CB  . PHE B  1 6   ? 50.24119 -7.75971  -49.88545 1.000 21.40457 ? 6   PHE B CB  1 
ATOM   4131 C  CG  . PHE B  1 6   ? 49.09709 -7.13301  -49.13730 1.000 23.33673 ? 6   PHE B CG  1 
ATOM   4132 C  CD1 . PHE B  1 6   ? 48.26731 -6.20634  -49.75265 1.000 23.51019 ? 6   PHE B CD1 1 
ATOM   4133 C  CD2 . PHE B  1 6   ? 48.84030 -7.48465  -47.82341 1.000 21.04437 ? 6   PHE B CD2 1 
ATOM   4134 C  CE1 . PHE B  1 6   ? 47.21037 -5.63690  -49.06753 1.000 18.27069 ? 6   PHE B CE1 1 
ATOM   4135 C  CE2 . PHE B  1 6   ? 47.78505 -6.91730  -47.13238 1.000 27.81244 ? 6   PHE B CE2 1 
ATOM   4136 C  CZ  . PHE B  1 6   ? 46.96959 -5.99244  -47.75535 1.000 22.11046 ? 6   PHE B CZ  1 
ATOM   4137 N  N   . VAL B  1 7   ? 50.64427 -9.76469  -53.00973 1.000 16.62079 ? 7   VAL B N   1 
ATOM   4138 C  CA  . VAL B  1 7   ? 51.59354 -10.63762 -53.69118 1.000 19.18405 ? 7   VAL B CA  1 
ATOM   4139 C  C   . VAL B  1 7   ? 51.97324 -10.13758 -55.07599 1.000 26.44227 ? 7   VAL B C   1 
ATOM   4140 O  O   . VAL B  1 7   ? 52.88264 -10.71245 -55.69359 1.000 27.16618 ? 7   VAL B O   1 
ATOM   4141 C  CB  . VAL B  1 7   ? 51.06744 -12.08654 -53.78040 1.000 19.49593 ? 7   VAL B CB  1 
ATOM   4142 C  CG1 . VAL B  1 7   ? 50.89601 -12.67190 -52.38777 1.000 23.48638 ? 7   VAL B CG1 1 
ATOM   4143 C  CG2 . VAL B  1 7   ? 49.75835 -12.13237 -54.54853 1.000 21.23818 ? 7   VAL B CG2 1 
ATOM   4144 N  N   . ASP B  1 8   ? 51.32158 -9.09544  -55.58737 1.000 26.12632 ? 8   ASP B N   1 
ATOM   4145 C  CA  . ASP B  1 8   ? 51.64682 -8.51514  -56.88230 1.000 19.87117 ? 8   ASP B CA  1 
ATOM   4146 C  C   . ASP B  1 8   ? 52.11687 -7.07949  -56.69828 1.000 22.73924 ? 8   ASP B C   1 
ATOM   4147 O  O   . ASP B  1 8   ? 51.57551 -6.34037  -55.87083 1.000 26.11394 ? 8   ASP B O   1 
ATOM   4148 C  CB  . ASP B  1 8   ? 50.44272 -8.54293  -57.82924 1.000 21.23090 ? 8   ASP B CB  1 
ATOM   4149 C  CG  . ASP B  1 8   ? 49.99906 -9.94896  -58.17156 1.000 27.87483 ? 8   ASP B CG  1 
ATOM   4150 O  OD1 . ASP B  1 8   ? 49.26827 -10.55806 -57.36260 1.000 25.48600 ? 8   ASP B OD1 1 
ATOM   4151 O  OD2 . ASP B  1 8   ? 50.37927 -10.44435 -59.25319 1.000 31.65405 ? 8   ASP B OD2 1 
ATOM   4152 N  N   . LYS B  1 9   ? 53.12244 -6.68798  -57.47495 1.000 22.83329 ? 9   LYS B N   1 
ATOM   4153 C  CA  . LYS B  1 9   ? 53.62105 -5.32264  -57.41589 1.000 22.09436 ? 9   LYS B CA  1 
ATOM   4154 C  C   . LYS B  1 9   ? 52.61958 -4.35189  -58.03220 1.000 23.90543 ? 9   LYS B C   1 
ATOM   4155 O  O   . LYS B  1 9   ? 51.84731 -4.70343  -58.92818 1.000 19.41359 ? 9   LYS B O   1 
ATOM   4156 C  CB  . LYS B  1 9   ? 54.96124 -5.20960  -58.13617 1.000 26.62294 ? 9   LYS B CB  1 
ATOM   4157 C  CG  . LYS B  1 9   ? 56.15530 -5.65781  -57.31560 1.000 34.93661 ? 9   LYS B CG  1 
ATOM   4158 C  CD  . LYS B  1 9   ? 57.43308 -5.12446  -57.93234 1.000 41.43911 ? 9   LYS B CD  1 
ATOM   4159 C  CE  . LYS B  1 9   ? 57.25236 -3.66662  -58.34126 1.000 48.06848 ? 9   LYS B CE  1 
ATOM   4160 N  NZ  . LYS B  1 9   ? 58.45662 -3.10771  -59.01726 1.000 59.71432 ? 9   LYS B NZ  1 
ATOM   4161 N  N   . LEU B  1 10  ? 52.64643 -3.11751  -57.54490 1.000 19.29076 ? 10  LEU B N   1 
ATOM   4162 C  CA  . LEU B  1 10  ? 51.70461 -2.09686  -57.99647 1.000 18.00021 ? 10  LEU B CA  1 
ATOM   4163 C  C   . LEU B  1 10  ? 52.05994 -1.61851  -59.39847 1.000 15.58672 ? 10  LEU B C   1 
ATOM   4164 O  O   . LEU B  1 10  ? 53.13442 -1.03449  -59.58923 1.000 22.69918 ? 10  LEU B O   1 
ATOM   4165 C  CB  . LEU B  1 10  ? 51.69904 -0.91843  -57.02767 1.000 18.52163 ? 10  LEU B CB  1 
ATOM   4166 C  CG  . LEU B  1 10  ? 50.84965 0.27803   -57.46241 1.000 20.15866 ? 10  LEU B CG  1 
ATOM   4167 C  CD1 . LEU B  1 10  ? 49.37581 -0.09964  -57.49502 1.000 17.60834 ? 10  LEU B CD1 1 
ATOM   4168 C  CD2 . LEU B  1 10  ? 51.08550 1.48268   -56.56014 1.000 21.54902 ? 10  LEU B CD2 1 
ATOM   4169 N  N   . PRO B  1 11  ? 51.20251 -1.82532  -60.39434 1.000 15.33497 ? 11  PRO B N   1 
ATOM   4170 C  CA  . PRO B  1 11  ? 51.52238 -1.35922  -61.74642 1.000 11.89860 ? 11  PRO B CA  1 
ATOM   4171 C  C   . PRO B  1 11  ? 51.38586 0.14966   -61.86102 1.000 17.97366 ? 11  PRO B C   1 
ATOM   4172 O  O   . PRO B  1 11  ? 50.53366 0.77421   -61.22516 1.000 23.84670 ? 11  PRO B O   1 
ATOM   4173 C  CB  . PRO B  1 11  ? 50.48742 -2.07271  -62.62911 1.000 12.15846 ? 11  PRO B CB  1 
ATOM   4174 C  CG  . PRO B  1 11  ? 49.81264 -3.08895  -61.73700 1.000 15.32972 ? 11  PRO B CG  1 
ATOM   4175 C  CD  . PRO B  1 11  ? 49.92105 -2.54383  -60.35109 1.000 17.22949 ? 11  PRO B CD  1 
ATOM   4176 N  N   . ILE B  1 12  ? 52.24370 0.73360   -62.68423 1.000 14.16465 ? 12  ILE B N   1 
ATOM   4177 C  CA  . ILE B  1 12  ? 52.16926 2.14476   -63.04509 1.000 15.99046 ? 12  ILE B CA  1 
ATOM   4178 C  C   . ILE B  1 12  ? 51.80497 2.22059   -64.52338 1.000 17.89301 ? 12  ILE B C   1 
ATOM   4179 O  O   . ILE B  1 12  ? 52.57342 1.73947   -65.36681 1.000 15.33442 ? 12  ILE B O   1 
ATOM   4180 C  CB  . ILE B  1 12  ? 53.48988 2.87875   -62.76429 1.000 22.19119 ? 12  ILE B CB  1 
ATOM   4181 C  CG1 . ILE B  1 12  ? 53.90789 2.69066   -61.30430 1.000 21.36911 ? 12  ILE B CG1 1 
ATOM   4182 C  CG2 . ILE B  1 12  ? 53.35434 4.35831   -63.09636 1.000 17.07564 ? 12  ILE B CG2 1 
ATOM   4183 C  CD1 . ILE B  1 12  ? 52.92846 3.26753   -60.30525 1.000 23.13816 ? 12  ILE B CD1 1 
ATOM   4184 N  N   . PRO B  1 13  ? 50.65178 2.78208   -64.88156 1.000 21.87128 ? 13  PRO B N   1 
ATOM   4185 C  CA  . PRO B  1 13  ? 50.29410 2.88925   -66.30251 1.000 17.57393 ? 13  PRO B CA  1 
ATOM   4186 C  C   . PRO B  1 13  ? 51.30630 3.73143   -67.06611 1.000 17.71728 ? 13  PRO B C   1 
ATOM   4187 O  O   . PRO B  1 13  ? 51.69854 4.81507   -66.62735 1.000 20.71949 ? 13  PRO B O   1 
ATOM   4188 C  CB  . PRO B  1 13  ? 48.91224 3.55241   -66.27120 1.000 17.62322 ? 13  PRO B CB  1 
ATOM   4189 C  CG  . PRO B  1 13  ? 48.37133 3.23892   -64.91072 1.000 20.58042 ? 13  PRO B CG  1 
ATOM   4190 C  CD  . PRO B  1 13  ? 49.56096 3.22619   -63.99716 1.000 17.39053 ? 13  PRO B CD  1 
ATOM   4191 N  N   . LYS B  1 14  ? 51.73667 3.21291   -68.21342 1.000 19.72492 ? 14  LYS B N   1 
ATOM   4192 C  CA  . LYS B  1 14  ? 52.68207 3.93246   -69.05438 1.000 17.46298 ? 14  LYS B CA  1 
ATOM   4193 C  C   . LYS B  1 14  ? 52.05821 5.21630   -69.58451 1.000 18.03336 ? 14  LYS B C   1 
ATOM   4194 O  O   . LYS B  1 14  ? 50.86934 5.26100   -69.91439 1.000 18.67640 ? 14  LYS B O   1 
ATOM   4195 C  CB  . LYS B  1 14  ? 53.12906 3.05015   -70.22176 1.000 26.99516 ? 14  LYS B CB  1 
ATOM   4196 C  CG  . LYS B  1 14  ? 54.39888 2.25152   -69.97304 1.000 26.86054 ? 14  LYS B CG  1 
ATOM   4197 C  CD  . LYS B  1 14  ? 54.67241 1.30390   -71.13344 1.000 38.10873 ? 14  LYS B CD  1 
ATOM   4198 C  CE  . LYS B  1 14  ? 56.15131 0.96300   -71.25165 1.000 61.31228 ? 14  LYS B CE  1 
ATOM   4199 N  NZ  . LYS B  1 14  ? 56.79535 1.68203   -72.38971 1.000 55.57104 ? 14  LYS B NZ  1 
ATOM   4200 N  N   . VAL B  1 15  ? 52.86988 6.27142   -69.65836 1.000 17.27224 ? 15  VAL B N   1 
ATOM   4201 C  CA  . VAL B  1 15  ? 52.42345 7.50518   -70.28964 1.000 18.26117 ? 15  VAL B CA  1 
ATOM   4202 C  C   . VAL B  1 15  ? 52.23126 7.25679   -71.77924 1.000 21.33433 ? 15  VAL B C   1 
ATOM   4203 O  O   . VAL B  1 15  ? 53.01103 6.53362   -72.41349 1.000 23.16409 ? 15  VAL B O   1 
ATOM   4204 C  CB  . VAL B  1 15  ? 53.42960 8.63889   -70.02733 1.000 18.97540 ? 15  VAL B CB  1 
ATOM   4205 C  CG1 . VAL B  1 15  ? 52.95247 9.94259   -70.65353 1.000 15.87664 ? 15  VAL B CG1 1 
ATOM   4206 C  CG2 . VAL B  1 15  ? 53.64509 8.81399   -68.53140 1.000 22.92850 ? 15  VAL B CG2 1 
ATOM   4207 N  N   . LEU B  1 16  ? 51.17458 7.83336   -72.34311 1.000 17.82456 ? 16  LEU B N   1 
ATOM   4208 C  CA  . LEU B  1 16  ? 50.84972 7.59871   -73.74234 1.000 18.76038 ? 16  LEU B CA  1 
ATOM   4209 C  C   . LEU B  1 16  ? 51.66926 8.51672   -74.63937 1.000 17.09272 ? 16  LEU B C   1 
ATOM   4210 O  O   . LEU B  1 16  ? 51.78379 9.71758   -74.37688 1.000 23.55960 ? 16  LEU B O   1 
ATOM   4211 C  CB  . LEU B  1 16  ? 49.35825 7.81533   -73.98705 1.000 22.57694 ? 16  LEU B CB  1 
ATOM   4212 C  CG  . LEU B  1 16  ? 48.87120 7.47641   -75.39588 1.000 23.95093 ? 16  LEU B CG  1 
ATOM   4213 C  CD1 . LEU B  1 16  ? 49.15715 6.02085   -75.72548 1.000 19.75210 ? 16  LEU B CD1 1 
ATOM   4214 C  CD2 . LEU B  1 16  ? 47.39374 7.77033   -75.52230 1.000 22.01015 ? 16  LEU B CD2 1 
ATOM   4215 N  N   . LYS B  1 17  ? 52.24122 7.94736   -75.69710 1.000 24.66424 ? 17  LYS B N   1 
ATOM   4216 C  CA  . LYS B  1 17  ? 52.98367 8.76256   -76.64989 1.000 21.20783 ? 17  LYS B CA  1 
ATOM   4217 C  C   . LYS B  1 17  ? 52.07064 9.19538   -77.79387 1.000 20.87975 ? 17  LYS B C   1 
ATOM   4218 O  O   . LYS B  1 17  ? 51.26943 8.39467   -78.28614 1.000 20.14882 ? 17  LYS B O   1 
ATOM   4219 C  CB  . LYS B  1 17  ? 54.17360 7.99205   -77.21421 1.000 18.24140 ? 17  LYS B CB  1 
ATOM   4220 C  CG  . LYS B  1 17  ? 55.05822 7.34970   -76.16095 1.000 30.49274 ? 17  LYS B CG  1 
ATOM   4221 C  CD  . LYS B  1 17  ? 55.62488 8.37686   -75.19213 1.000 38.24009 ? 17  LYS B CD  1 
ATOM   4222 C  CE  . LYS B  1 17  ? 55.39727 7.92836   -73.75330 1.000 38.50557 ? 17  LYS B CE  1 
ATOM   4223 N  NZ  . LYS B  1 17  ? 56.17706 8.71048   -72.75120 1.000 28.00920 ? 17  LYS B NZ  1 
ATOM   4224 N  N   . PRO B  1 18  ? 52.15935 10.44835  -78.22859 1.000 18.13603 ? 18  PRO B N   1 
ATOM   4225 C  CA  . PRO B  1 18  ? 51.31437 10.89693  -79.33840 1.000 18.42453 ? 18  PRO B CA  1 
ATOM   4226 C  C   . PRO B  1 18  ? 51.79930 10.34916  -80.67005 1.000 18.94842 ? 18  PRO B C   1 
ATOM   4227 O  O   . PRO B  1 18  ? 52.98412 10.06493  -80.86150 1.000 18.85328 ? 18  PRO B O   1 
ATOM   4228 C  CB  . PRO B  1 18  ? 51.44118 12.42294  -79.28518 1.000 18.03310 ? 18  PRO B CB  1 
ATOM   4229 C  CG  . PRO B  1 18  ? 52.77213 12.65953  -78.65300 1.000 17.43059 ? 18  PRO B CG  1 
ATOM   4230 C  CD  . PRO B  1 18  ? 52.96678 11.54366  -77.66386 1.000 18.27645 ? 18  PRO B CD  1 
ATOM   4231 N  N   . HIS B  1 19  ? 50.85234 10.19043  -81.59756 1.000 20.21054 ? 19  HIS B N   1 
ATOM   4232 C  CA  . HIS B  1 19  ? 51.21455 9.81428   -82.95922 1.000 18.70911 ? 19  HIS B CA  1 
ATOM   4233 C  C   . HIS B  1 19  ? 51.92515 10.95230  -83.68046 1.000 19.48195 ? 19  HIS B C   1 
ATOM   4234 O  O   . HIS B  1 19  ? 52.80926 10.70467  -84.50788 1.000 22.35163 ? 19  HIS B O   1 
ATOM   4235 C  CB  . HIS B  1 19  ? 49.96998 9.38775   -83.73885 1.000 17.29894 ? 19  HIS B CB  1 
ATOM   4236 C  CG  . HIS B  1 19  ? 49.53581 7.98081   -83.46691 1.000 19.06538 ? 19  HIS B CG  1 
ATOM   4237 N  ND1 . HIS B  1 19  ? 49.61710 7.40340   -82.21800 1.000 20.67096 ? 19  HIS B ND1 1 
ATOM   4238 C  CD2 . HIS B  1 19  ? 49.01222 7.03639   -84.28408 1.000 13.32402 ? 19  HIS B CD2 1 
ATOM   4239 C  CE1 . HIS B  1 19  ? 49.16413 6.16360   -82.27821 1.000 18.94058 ? 19  HIS B CE1 1 
ATOM   4240 N  NE2 . HIS B  1 19  ? 48.79085 5.91630   -83.52083 1.000 17.03980 ? 19  HIS B NE2 1 
ATOM   4241 N  N   . SER B  1 20  ? 51.55888 12.19578  -83.37900 1.000 16.14565 ? 20  SER B N   1 
ATOM   4242 C  CA  . SER B  1 20  ? 52.17161 13.36087  -83.99853 1.000 17.95975 ? 20  SER B CA  1 
ATOM   4243 C  C   . SER B  1 20  ? 51.98356 14.55476  -83.07265 1.000 22.51304 ? 20  SER B C   1 
ATOM   4244 O  O   . SER B  1 20  ? 50.91314 14.72683  -82.48416 1.000 21.17970 ? 20  SER B O   1 
ATOM   4245 C  CB  . SER B  1 20  ? 51.56190 13.64410  -85.37658 1.000 18.36872 ? 20  SER B CB  1 
ATOM   4246 O  OG  . SER B  1 20  ? 52.21108 14.73268  -86.00896 1.000 27.88895 ? 20  SER B OG  1 
ATOM   4247 N  N   . LYS B  1 21  ? 53.02646 15.37249  -82.94837 1.000 22.35223 ? 21  LYS B N   1 
ATOM   4248 C  CA  . LYS B  1 21  ? 53.01279 16.51419  -82.04073 1.000 24.08850 ? 21  LYS B CA  1 
ATOM   4249 C  C   . LYS B  1 21  ? 53.65728 17.70151  -82.73602 1.000 27.42570 ? 21  LYS B C   1 
ATOM   4250 O  O   . LYS B  1 21  ? 54.82383 17.63111  -83.13450 1.000 32.21399 ? 21  LYS B O   1 
ATOM   4251 C  CB  . LYS B  1 21  ? 53.74358 16.18480  -80.73448 1.000 23.39198 ? 21  LYS B CB  1 
ATOM   4252 C  CG  . LYS B  1 21  ? 53.81989 17.33178  -79.73892 1.000 18.94212 ? 21  LYS B CG  1 
ATOM   4253 C  CD  . LYS B  1 21  ? 54.13669 16.81119  -78.34426 1.000 24.38895 ? 21  LYS B CD  1 
ATOM   4254 C  CE  . LYS B  1 21  ? 54.59935 17.92289  -77.41564 1.000 16.18007 ? 21  LYS B CE  1 
ATOM   4255 N  NZ  . LYS B  1 21  ? 53.61261 19.03227  -77.32466 1.000 23.66177 ? 21  LYS B NZ  1 
ATOM   4256 N  N   . SER B  1 22  ? 52.89987 18.78550  -82.88159 1.000 29.07309 ? 22  SER B N   1 
ATOM   4257 C  CA  . SER B  1 22  ? 53.37401 20.00005  -83.52772 1.000 33.72314 ? 22  SER B CA  1 
ATOM   4258 C  C   . SER B  1 22  ? 53.06518 21.19682  -82.63622 1.000 37.18103 ? 22  SER B C   1 
ATOM   4259 O  O   . SER B  1 22  ? 52.51638 21.06081  -81.53873 1.000 37.43015 ? 22  SER B O   1 
ATOM   4260 C  CB  . SER B  1 22  ? 52.73747 20.17917  -84.91204 1.000 41.73776 ? 22  SER B CB  1 
ATOM   4261 O  OG  . SER B  1 22  ? 51.36027 20.49744  -84.80293 1.000 41.87183 ? 22  SER B OG  1 
ATOM   4262 N  N   . LYS B  1 23  ? 53.42888 22.38504  -83.12384 1.000 49.54321 ? 23  LYS B N   1 
ATOM   4263 C  CA  . LYS B  1 23  ? 53.11654 23.61498  -82.40383 1.000 47.52333 ? 23  LYS B CA  1 
ATOM   4264 C  C   . LYS B  1 23  ? 51.61426 23.84793  -82.32983 1.000 39.61480 ? 23  LYS B C   1 
ATOM   4265 O  O   . LYS B  1 23  ? 51.11902 24.40171  -81.34159 1.000 37.82408 ? 23  LYS B O   1 
ATOM   4266 C  CB  . LYS B  1 23  ? 53.80299 24.81020  -83.07351 1.000 48.14753 ? 23  LYS B CB  1 
ATOM   4267 C  CG  . LYS B  1 23  ? 55.27627 25.01161  -82.71265 1.000 54.14373 ? 23  LYS B CG  1 
ATOM   4268 C  CD  . LYS B  1 23  ? 56.16350 23.87509  -83.21079 1.000 58.60246 ? 23  LYS B CD  1 
ATOM   4269 C  CE  . LYS B  1 23  ? 56.01245 23.65848  -84.70943 1.000 41.47152 ? 23  LYS B CE  1 
ATOM   4270 N  NZ  . LYS B  1 23  ? 56.62664 22.37229  -85.14056 1.000 31.79903 ? 23  LYS B NZ  1 
ATOM   4271 N  N   . GLU B  1 24  ? 50.87727 23.42630  -83.35781 1.000 43.63845 ? 24  GLU B N   1 
ATOM   4272 C  CA  . GLU B  1 24  ? 49.43557 23.63560  -83.39206 1.000 47.34425 ? 24  GLU B CA  1 
ATOM   4273 C  C   . GLU B  1 24  ? 48.70460 22.64037  -82.49897 1.000 50.67227 ? 24  GLU B C   1 
ATOM   4274 O  O   . GLU B  1 24  ? 47.84734 23.02646  -81.69603 1.000 41.17131 ? 24  GLU B O   1 
ATOM   4275 C  CB  . GLU B  1 24  ? 48.92509 23.51683  -84.82976 1.000 52.60474 ? 24  GLU B CB  1 
ATOM   4276 C  CG  . GLU B  1 24  ? 49.79102 24.20130  -85.87251 1.000 59.92508 ? 24  GLU B CG  1 
ATOM   4277 C  CD  . GLU B  1 24  ? 49.70797 23.51998  -87.22767 1.000 68.46342 ? 24  GLU B CD  1 
ATOM   4278 O  OE1 . GLU B  1 24  ? 49.67042 22.27116  -87.26327 1.000 53.04864 ? 24  GLU B OE1 1 
ATOM   4279 O  OE2 . GLU B  1 24  ? 49.67434 24.23008  -88.25534 1.000 61.82940 ? 24  GLU B OE2 1 
ATOM   4280 N  N   . MET B  1 25  ? 49.03598 21.35661  -82.62130 1.000 39.33959 ? 25  MET B N   1 
ATOM   4281 C  CA  . MET B  1 25  ? 48.19666 20.30240  -82.07666 1.000 29.24899 ? 25  MET B CA  1 
ATOM   4282 C  C   . MET B  1 25  ? 49.05789 19.11310  -81.67586 1.000 26.20569 ? 25  MET B C   1 
ATOM   4283 O  O   . MET B  1 25  ? 50.13898 18.89566  -82.22937 1.000 29.58711 ? 25  MET B O   1 
ATOM   4284 C  CB  . MET B  1 25  ? 47.14198 19.88510  -83.10972 1.000 30.62563 ? 25  MET B CB  1 
ATOM   4285 C  CG  . MET B  1 25  ? 46.01772 19.01562  -82.58772 1.000 31.35247 ? 25  MET B CG  1 
ATOM   4286 S  SD  . MET B  1 25  ? 44.91054 18.54228  -83.93015 1.000 72.52680 ? 25  MET B SD  1 
ATOM   4287 C  CE  . MET B  1 25  ? 46.02616 17.60420  -84.97333 1.000 17.78870 ? 25  MET B CE  1 
ATOM   4288 N  N   . THR B  1 26  ? 48.56779 18.34911  -80.70017 1.000 20.94015 ? 26  THR B N   1 
ATOM   4289 C  CA  . THR B  1 26  ? 49.17280 17.08498  -80.28957 1.000 21.10315 ? 26  THR B CA  1 
ATOM   4290 C  C   . THR B  1 26  ? 48.14972 15.98477  -80.54177 1.000 21.90118 ? 26  THR B C   1 
ATOM   4291 O  O   . THR B  1 26  ? 47.12721 15.91160  -79.85129 1.000 22.35978 ? 26  THR B O   1 
ATOM   4292 C  CB  . THR B  1 26  ? 49.59748 17.11643  -78.82179 1.000 20.53038 ? 26  THR B CB  1 
ATOM   4293 O  OG1 . THR B  1 26  ? 50.51886 18.19292  -78.61032 1.000 19.88279 ? 26  THR B OG1 1 
ATOM   4294 C  CG2 . THR B  1 26  ? 50.26887 15.80731  -78.43806 1.000 18.63546 ? 26  THR B CG2 1 
ATOM   4295 N  N   . TYR B  1 27  ? 48.42618 15.13150  -81.52333 1.000 18.10574 ? 27  TYR B N   1 
ATOM   4296 C  CA  . TYR B  1 27  ? 47.46005 14.16038  -82.01836 1.000 17.27289 ? 27  TYR B CA  1 
ATOM   4297 C  C   . TYR B  1 27  ? 47.72389 12.78620  -81.41579 1.000 16.49246 ? 27  TYR B C   1 
ATOM   4298 O  O   . TYR B  1 27  ? 48.85000 12.28115  -81.47377 1.000 17.40008 ? 27  TYR B O   1 
ATOM   4299 C  CB  . TYR B  1 27  ? 47.51225 14.09030  -83.54527 1.000 19.29727 ? 27  TYR B CB  1 
ATOM   4300 C  CG  . TYR B  1 27  ? 46.53548 13.11328  -84.15357 1.000 21.26036 ? 27  TYR B CG  1 
ATOM   4301 C  CD1 . TYR B  1 27  ? 45.17049 13.37138  -84.14797 1.000 21.94974 ? 27  TYR B CD1 1 
ATOM   4302 C  CD2 . TYR B  1 27  ? 46.97853 11.93737  -84.74338 1.000 17.91719 ? 27  TYR B CD2 1 
ATOM   4303 C  CE1 . TYR B  1 27  ? 44.27277 12.48046  -84.70593 1.000 18.93478 ? 27  TYR B CE1 1 
ATOM   4304 C  CE2 . TYR B  1 27  ? 46.09023 11.04201  -85.30469 1.000 19.29906 ? 27  TYR B CE2 1 
ATOM   4305 C  CZ  . TYR B  1 27  ? 44.73827 11.31776  -85.28354 1.000 23.35921 ? 27  TYR B CZ  1 
ATOM   4306 O  OH  . TYR B  1 27  ? 43.85024 10.42689  -85.84236 1.000 21.19671 ? 27  TYR B OH  1 
ATOM   4307 N  N   . TYR B  1 28  ? 46.68100 12.18545  -80.84717 1.000 18.13592 ? 28  TYR B N   1 
ATOM   4308 C  CA  . TYR B  1 28  ? 46.74069 10.84919  -80.27583 1.000 18.73904 ? 28  TYR B CA  1 
ATOM   4309 C  C   . TYR B  1 28  ? 45.79248 9.91731   -81.02039 1.000 18.35799 ? 28  TYR B C   1 
ATOM   4310 O  O   . TYR B  1 28  ? 44.83892 10.35264  -81.67158 1.000 19.73986 ? 28  TYR B O   1 
ATOM   4311 C  CB  . TYR B  1 28  ? 46.37004 10.85390  -78.78530 1.000 17.70158 ? 28  TYR B CB  1 
ATOM   4312 C  CG  . TYR B  1 28  ? 47.40516 11.45892  -77.86535 1.000 15.12983 ? 28  TYR B CG  1 
ATOM   4313 C  CD1 . TYR B  1 28  ? 48.38719 10.67090  -77.28230 1.000 15.44796 ? 28  TYR B CD1 1 
ATOM   4314 C  CD2 . TYR B  1 28  ? 47.38633 12.81327  -77.56154 1.000 17.16600 ? 28  TYR B CD2 1 
ATOM   4315 C  CE1 . TYR B  1 28  ? 49.33052 11.21641  -76.43199 1.000 20.85967 ? 28  TYR B CE1 1 
ATOM   4316 C  CE2 . TYR B  1 28  ? 48.32534 13.36785  -76.71388 1.000 19.62725 ? 28  TYR B CE2 1 
ATOM   4317 C  CZ  . TYR B  1 28  ? 49.29643 12.56575  -76.15262 1.000 20.57565 ? 28  TYR B CZ  1 
ATOM   4318 O  OH  . TYR B  1 28  ? 50.23328 13.11479  -75.30559 1.000 18.16844 ? 28  TYR B OH  1 
ATOM   4319 N  N   . GLU B  1 29  ? 46.06502 8.61895   -80.90954 1.000 17.05856 ? 29  GLU B N   1 
ATOM   4320 C  CA  . GLU B  1 29  ? 45.16153 7.58364   -81.39910 1.000 15.05050 ? 29  GLU B CA  1 
ATOM   4321 C  C   . GLU B  1 29  ? 45.11214 6.46664   -80.37102 1.000 19.71600 ? 29  GLU B C   1 
ATOM   4322 O  O   . GLU B  1 29  ? 46.14951 5.89207   -80.02540 1.000 21.28665 ? 29  GLU B O   1 
ATOM   4323 C  CB  . GLU B  1 29  ? 45.60201 7.04085   -82.76044 1.000 15.54787 ? 29  GLU B CB  1 
ATOM   4324 C  CG  . GLU B  1 29  ? 45.27014 7.95904   -83.91695 1.000 24.19147 ? 29  GLU B CG  1 
ATOM   4325 C  CD  . GLU B  1 29  ? 45.25680 7.24042   -85.24830 1.000 18.93726 ? 29  GLU B CD  1 
ATOM   4326 O  OE1 . GLU B  1 29  ? 45.41762 6.00126   -85.26235 1.000 17.37443 ? 29  GLU B OE1 1 
ATOM   4327 O  OE2 . GLU B  1 29  ? 45.08183 7.91828   -86.28101 1.000 20.93382 ? 29  GLU B OE2 1 
ATOM   4328 N  N   . VAL B  1 30  ? 43.91166 6.16951   -79.88034 1.000 15.05421 ? 30  VAL B N   1 
ATOM   4329 C  CA  . VAL B  1 30  ? 43.69316 5.13645   -78.87634 1.000 13.00551 ? 30  VAL B CA  1 
ATOM   4330 C  C   . VAL B  1 30  ? 42.60800 4.20310   -79.38966 1.000 14.62059 ? 30  VAL B C   1 
ATOM   4331 O  O   . VAL B  1 30  ? 41.56536 4.66357   -79.86829 1.000 15.90084 ? 30  VAL B O   1 
ATOM   4332 C  CB  . VAL B  1 30  ? 43.29208 5.73725   -77.51533 1.000 13.66744 ? 30  VAL B CB  1 
ATOM   4333 C  CG1 . VAL B  1 30  ? 43.16054 4.64812   -76.47678 1.000 14.31940 ? 30  VAL B CG1 1 
ATOM   4334 C  CG2 . VAL B  1 30  ? 44.30658 6.77847   -77.07177 1.000 12.87348 ? 30  VAL B CG2 1 
ATOM   4335 N  N   . THR B  1 31  ? 42.85151 2.89814   -79.29373 1.000 14.42065 ? 31  THR B N   1 
ATOM   4336 C  CA  . THR B  1 31  ? 41.92187 1.88790   -79.77801 1.000 19.60930 ? 31  THR B CA  1 
ATOM   4337 C  C   . THR B  1 31  ? 41.39056 1.07006   -78.60990 1.000 20.49976 ? 31  THR B C   1 
ATOM   4338 O  O   . THR B  1 31  ? 42.13723 0.72821   -77.68733 1.000 22.53173 ? 31  THR B O   1 
ATOM   4339 C  CB  . THR B  1 31  ? 42.58669 0.95257   -80.79745 1.000 18.58543 ? 31  THR B CB  1 
ATOM   4340 O  OG1 . THR B  1 31  ? 43.51186 0.09083   -80.12451 1.000 28.43949 ? 31  THR B OG1 1 
ATOM   4341 C  CG2 . THR B  1 31  ? 43.33199 1.75301   -81.85138 1.000 10.93319 ? 31  THR B CG2 1 
ATOM   4342 N  N   . MET B  1 32  ? 40.09757 0.75932   -78.65644 1.000 18.52501 ? 32  MET B N   1 
ATOM   4343 C  CA  . MET B  1 32  ? 39.45807 -0.08918  -77.65675 1.000 18.71160 ? 32  MET B CA  1 
ATOM   4344 C  C   . MET B  1 32  ? 39.46406 -1.51974  -78.18007 1.000 24.33098 ? 32  MET B C   1 
ATOM   4345 O  O   . MET B  1 32  ? 38.81359 -1.82228  -79.18591 1.000 20.12234 ? 32  MET B O   1 
ATOM   4346 C  CB  . MET B  1 32  ? 38.03610 0.38639   -77.37336 1.000 16.61127 ? 32  MET B CB  1 
ATOM   4347 C  CG  . MET B  1 32  ? 37.92334 1.87398   -77.11829 1.000 20.93320 ? 32  MET B CG  1 
ATOM   4348 S  SD  . MET B  1 32  ? 36.21420 2.43435   -77.10955 1.000 23.78364 ? 32  MET B SD  1 
ATOM   4349 C  CE  . MET B  1 32  ? 36.24302 3.61971   -78.45196 1.000 17.59126 ? 32  MET B CE  1 
ATOM   4350 N  N   . LYS B  1 33  ? 40.19649 -2.39977  -77.50291 1.000 25.92282 ? 33  LYS B N   1 
ATOM   4351 C  CA  . LYS B  1 33  ? 40.37782 -3.76731  -77.96294 1.000 22.70640 ? 33  LYS B CA  1 
ATOM   4352 C  C   . LYS B  1 33  ? 40.01961 -4.74567  -76.85464 1.000 20.26331 ? 33  LYS B C   1 
ATOM   4353 O  O   . LYS B  1 33  ? 40.19512 -4.45944  -75.66750 1.000 20.86175 ? 33  LYS B O   1 
ATOM   4354 C  CB  . LYS B  1 33  ? 41.82271 -4.01027  -78.43023 1.000 19.06430 ? 33  LYS B CB  1 
ATOM   4355 C  CG  . LYS B  1 33  ? 42.36625 -2.89748  -79.31386 1.000 29.56168 ? 33  LYS B CG  1 
ATOM   4356 C  CD  . LYS B  1 33  ? 43.59896 -3.32363  -80.09262 1.000 29.59165 ? 33  LYS B CD  1 
ATOM   4357 C  CE  . LYS B  1 33  ? 44.74347 -3.69206  -79.16687 1.000 39.73902 ? 33  LYS B CE  1 
ATOM   4358 N  NZ  . LYS B  1 33  ? 46.06243 -3.43411  -79.80996 1.000 36.27704 ? 33  LYS B NZ  1 
ATOM   4359 N  N   . GLU B  1 34  ? 39.50305 -5.90253  -77.25742 1.000 23.24701 ? 34  GLU B N   1 
ATOM   4360 C  CA  . GLU B  1 34  ? 39.26946 -6.99196  -76.32336 1.000 22.91029 ? 34  GLU B CA  1 
ATOM   4361 C  C   . GLU B  1 34  ? 40.55184 -7.79043  -76.14000 1.000 22.77205 ? 34  GLU B C   1 
ATOM   4362 O  O   . GLU B  1 34  ? 41.25573 -8.09275  -77.10772 1.000 26.24359 ? 34  GLU B O   1 
ATOM   4363 C  CB  . GLU B  1 34  ? 38.15000 -7.90348  -76.82443 1.000 22.58610 ? 34  GLU B CB  1 
ATOM   4364 C  CG  . GLU B  1 34  ? 37.74573 -8.98600  -75.83668 1.000 26.90681 ? 34  GLU B CG  1 
ATOM   4365 C  CD  . GLU B  1 34  ? 36.77209 -9.98227  -76.43157 1.000 34.96097 ? 34  GLU B CD  1 
ATOM   4366 O  OE1 . GLU B  1 34  ? 36.99961 -10.42545 -77.57738 1.000 41.64995 ? 34  GLU B OE1 1 
ATOM   4367 O  OE2 . GLU B  1 34  ? 35.77516 -10.31666 -75.75802 1.000 36.71712 ? 34  GLU B OE2 1 
ATOM   4368 N  N   . PHE B  1 35  ? 40.85568 -8.12701  -74.89093 1.000 23.16438 ? 35  PHE B N   1 
ATOM   4369 C  CA  . PHE B  1 35  ? 42.09395 -8.82311  -74.57320 1.000 20.57262 ? 35  PHE B CA  1 
ATOM   4370 C  C   . PHE B  1 35  ? 41.95700 -9.45663  -73.19773 1.000 23.47861 ? 35  PHE B C   1 
ATOM   4371 O  O   . PHE B  1 35  ? 40.96877 -9.25077  -72.48879 1.000 19.83739 ? 35  PHE B O   1 
ATOM   4372 C  CB  . PHE B  1 35  ? 43.29439 -7.87337  -74.61735 1.000 16.72036 ? 35  PHE B CB  1 
ATOM   4373 C  CG  . PHE B  1 35  ? 43.23864 -6.78363  -73.58626 1.000 21.73603 ? 35  PHE B CG  1 
ATOM   4374 C  CD1 . PHE B  1 35  ? 42.46059 -5.65767  -73.79176 1.000 21.50560 ? 35  PHE B CD1 1 
ATOM   4375 C  CD2 . PHE B  1 35  ? 43.96179 -6.88573  -72.40981 1.000 24.93316 ? 35  PHE B CD2 1 
ATOM   4376 C  CE1 . PHE B  1 35  ? 42.40257 -4.65651  -72.84457 1.000 20.70226 ? 35  PHE B CE1 1 
ATOM   4377 C  CE2 . PHE B  1 35  ? 43.90872 -5.88500  -71.45905 1.000 20.67420 ? 35  PHE B CE2 1 
ATOM   4378 C  CZ  . PHE B  1 35  ? 43.12704 -4.76963  -71.67745 1.000 18.09160 ? 35  PHE B CZ  1 
ATOM   4379 N  N   . GLN B  1 36  ? 42.97195 -10.22953 -72.82802 1.000 27.49475 ? 36  GLN B N   1 
ATOM   4380 C  CA  . GLN B  1 36  ? 43.03960 -10.87113 -71.52537 1.000 24.72689 ? 36  GLN B CA  1 
ATOM   4381 C  C   . GLN B  1 36  ? 44.26474 -10.36782 -70.77870 1.000 20.97445 ? 36  GLN B C   1 
ATOM   4382 O  O   . GLN B  1 36  ? 45.33146 -10.17555 -71.37124 1.000 24.29405 ? 36  GLN B O   1 
ATOM   4383 C  CB  . GLN B  1 36  ? 43.07286 -12.39472 -71.66405 1.000 22.86668 ? 36  GLN B CB  1 
ATOM   4384 C  CG  . GLN B  1 36  ? 41.71517 -12.98172 -72.02227 1.000 30.80140 ? 36  GLN B CG  1 
ATOM   4385 C  CD  . GLN B  1 36  ? 41.81181 -14.29090 -72.77557 1.000 35.21557 ? 36  GLN B CD  1 
ATOM   4386 O  OE1 . GLN B  1 36  ? 42.66913 -15.12712 -72.49042 1.000 33.58295 ? 36  GLN B OE1 1 
ATOM   4387 N  NE2 . GLN B  1 36  ? 40.93017 -14.47318 -73.75201 1.000 51.54829 ? 36  GLN B NE2 1 
ATOM   4388 N  N   . GLN B  1 37  ? 44.09741 -10.13833 -69.47898 1.000 19.54101 ? 37  GLN B N   1 
ATOM   4389 C  CA  . GLN B  1 37  ? 45.15929 -9.59042  -68.64720 1.000 21.58906 ? 37  GLN B CA  1 
ATOM   4390 C  C   . GLN B  1 37  ? 45.05588 -10.20903 -67.26327 1.000 19.13495 ? 37  GLN B C   1 
ATOM   4391 O  O   . GLN B  1 37  ? 43.96145 -10.28505 -66.69754 1.000 21.12155 ? 37  GLN B O   1 
ATOM   4392 C  CB  . GLN B  1 37  ? 45.06157 -8.06212  -68.56756 1.000 21.71279 ? 37  GLN B CB  1 
ATOM   4393 C  CG  . GLN B  1 37  ? 46.12364 -7.40217  -67.70448 1.000 20.03277 ? 37  GLN B CG  1 
ATOM   4394 C  CD  . GLN B  1 37  ? 46.03507 -5.88758  -67.73617 1.000 18.86672 ? 37  GLN B CD  1 
ATOM   4395 O  OE1 . GLN B  1 37  ? 45.99217 -5.27828  -68.80587 1.000 16.10036 ? 37  GLN B OE1 1 
ATOM   4396 N  NE2 . GLN B  1 37  ? 45.99771 -5.27229  -66.56004 1.000 18.23481 ? 37  GLN B NE2 1 
ATOM   4397 N  N   . GLN B  1 38  ? 46.18890 -10.65639 -66.73007 1.000 20.23342 ? 38  GLN B N   1 
ATOM   4398 C  CA  . GLN B  1 38  ? 46.21449 -11.28909 -65.41824 1.000 21.65703 ? 38  GLN B CA  1 
ATOM   4399 C  C   . GLN B  1 38  ? 46.16014 -10.21474 -64.33958 1.000 24.67827 ? 38  GLN B C   1 
ATOM   4400 O  O   . GLN B  1 38  ? 47.04384 -9.35321  -64.26807 1.000 31.55715 ? 38  GLN B O   1 
ATOM   4401 C  CB  . GLN B  1 38  ? 47.46547 -12.14947 -65.26506 1.000 21.89976 ? 38  GLN B CB  1 
ATOM   4402 C  CG  . GLN B  1 38  ? 47.42836 -13.07552 -64.06662 1.000 23.18825 ? 38  GLN B CG  1 
ATOM   4403 C  CD  . GLN B  1 38  ? 48.73898 -13.80026 -63.84860 1.000 25.14049 ? 38  GLN B CD  1 
ATOM   4404 O  OE1 . GLN B  1 38  ? 49.80936 -13.28589 -64.17671 1.000 32.13177 ? 38  GLN B OE1 1 
ATOM   4405 N  NE2 . GLN B  1 38  ? 48.66273 -15.00400 -63.29398 1.000 22.69329 ? 38  GLN B NE2 1 
ATOM   4406 N  N   . LEU B  1 39  ? 45.12493 -10.26563 -63.50036 1.000 21.07104 ? 39  LEU B N   1 
ATOM   4407 C  CA  . LEU B  1 39  ? 44.91863 -9.24868  -62.47828 1.000 23.25455 ? 39  LEU B CA  1 
ATOM   4408 C  C   . LEU B  1 39  ? 45.40935 -9.66270  -61.09787 1.000 22.07230 ? 39  LEU B C   1 
ATOM   4409 O  O   . LEU B  1 39  ? 45.56246 -8.79617  -60.22946 1.000 23.86394 ? 39  LEU B O   1 
ATOM   4410 C  CB  . LEU B  1 39  ? 43.43360 -8.87578  -62.39855 1.000 22.33111 ? 39  LEU B CB  1 
ATOM   4411 C  CG  . LEU B  1 39  ? 42.82556 -8.40414  -63.72229 1.000 22.80284 ? 39  LEU B CG  1 
ATOM   4412 C  CD1 . LEU B  1 39  ? 41.40380 -7.90493  -63.52433 1.000 23.75214 ? 39  LEU B CD1 1 
ATOM   4413 C  CD2 . LEU B  1 39  ? 43.69239 -7.32887  -64.36138 1.000 20.43735 ? 39  LEU B CD2 1 
ATOM   4414 N  N   . HIS B  1 40  ? 45.65511 -10.95168 -60.87174 1.000 22.16585 ? 40  HIS B N   1 
ATOM   4415 C  CA  . HIS B  1 40  ? 46.23443 -11.42085 -59.62217 1.000 27.70106 ? 40  HIS B CA  1 
ATOM   4416 C  C   . HIS B  1 40  ? 47.18646 -12.56866 -59.91809 1.000 28.48008 ? 40  HIS B C   1 
ATOM   4417 O  O   . HIS B  1 40  ? 47.05964 -13.25580 -60.93446 1.000 26.23804 ? 40  HIS B O   1 
ATOM   4418 C  CB  . HIS B  1 40  ? 45.16119 -11.87171 -58.61965 1.000 26.81993 ? 40  HIS B CB  1 
ATOM   4419 C  CG  . HIS B  1 40  ? 45.70150 -12.18169 -57.25755 1.000 25.50761 ? 40  HIS B CG  1 
ATOM   4420 N  ND1 . HIS B  1 40  ? 46.10054 -13.44683 -56.88394 1.000 28.19296 ? 40  HIS B ND1 1 
ATOM   4421 C  CD2 . HIS B  1 40  ? 45.92055 -11.38694 -56.18361 1.000 25.80762 ? 40  HIS B CD2 1 
ATOM   4422 C  CE1 . HIS B  1 40  ? 46.53504 -13.41947 -55.63681 1.000 23.58745 ? 40  HIS B CE1 1 
ATOM   4423 N  NE2 . HIS B  1 40  ? 46.43457 -12.18171 -55.18819 1.000 22.03207 ? 40  HIS B NE2 1 
ATOM   4424 N  N   . ARG B  1 41  ? 48.14614 -12.76521 -59.00873 1.000 27.79044 ? 41  ARG B N   1 
ATOM   4425 C  CA  . ARG B  1 41  ? 49.15584 -13.80218 -59.19529 1.000 28.94865 ? 41  ARG B CA  1 
ATOM   4426 C  C   . ARG B  1 41  ? 48.52193 -15.17893 -59.35608 1.000 25.84608 ? 41  ARG B C   1 
ATOM   4427 O  O   . ARG B  1 41  ? 49.01819 -16.01283 -60.12261 1.000 21.40460 ? 41  ARG B O   1 
ATOM   4428 C  CB  . ARG B  1 41  ? 50.12521 -13.79641 -58.01496 1.000 25.21988 ? 41  ARG B CB  1 
ATOM   4429 C  CG  . ARG B  1 41  ? 51.21504 -14.85207 -58.08152 1.000 18.94659 ? 41  ARG B CG  1 
ATOM   4430 C  CD  . ARG B  1 41  ? 51.76592 -15.13360 -56.69317 1.000 19.81380 ? 41  ARG B CD  1 
ATOM   4431 N  NE  . ARG B  1 41  ? 50.75241 -15.72603 -55.82866 1.000 21.36008 ? 41  ARG B NE  1 
ATOM   4432 C  CZ  . ARG B  1 41  ? 50.89544 -15.90907 -54.52379 1.000 22.92235 ? 41  ARG B CZ  1 
ATOM   4433 N  NH1 . ARG B  1 41  ? 51.99713 -15.54028 -53.89106 1.000 28.05842 ? 41  ARG B NH1 1 
ATOM   4434 N  NH2 . ARG B  1 41  ? 49.90759 -16.47406 -53.83613 1.000 23.93969 ? 41  ARG B NH2 1 
ATOM   4435 N  N   . ASP B  1 42  ? 47.42028 -15.43343 -58.65140 1.000 23.59115 ? 42  ASP B N   1 
ATOM   4436 C  CA  . ASP B  1 42  ? 46.77447 -16.73923 -58.65283 1.000 25.60712 ? 42  ASP B CA  1 
ATOM   4437 C  C   . ASP B  1 42  ? 45.46996 -16.74281 -59.44155 1.000 25.95837 ? 42  ASP B C   1 
ATOM   4438 O  O   . ASP B  1 42  ? 44.63838 -17.63588 -59.25327 1.000 34.00348 ? 42  ASP B O   1 
ATOM   4439 C  CB  . ASP B  1 42  ? 46.53072 -17.20055 -57.21670 1.000 21.42563 ? 42  ASP B CB  1 
ATOM   4440 C  CG  . ASP B  1 42  ? 47.77029 -17.07768 -56.35100 1.000 27.97278 ? 42  ASP B CG  1 
ATOM   4441 O  OD1 . ASP B  1 42  ? 48.87945 -17.38137 -56.84448 1.000 25.17562 ? 42  ASP B OD1 1 
ATOM   4442 O  OD2 . ASP B  1 42  ? 47.63613 -16.67108 -55.17760 1.000 24.52688 ? 42  ASP B OD2 1 
ATOM   4443 N  N   . LEU B  1 43  ? 45.26975 -15.75655 -60.31829 1.000 26.50316 ? 43  LEU B N   1 
ATOM   4444 C  CA  . LEU B  1 43  ? 44.06877 -15.73437 -61.13551 1.000 25.24187 ? 43  LEU B CA  1 
ATOM   4445 C  C   . LEU B  1 43  ? 44.40502 -15.98084 -62.59918 1.000 25.60737 ? 43  LEU B C   1 
ATOM   4446 O  O   . LEU B  1 43  ? 45.41165 -15.46617 -63.09880 1.000 22.43767 ? 43  LEU B O   1 
ATOM   4447 C  CB  . LEU B  1 43  ? 43.32836 -14.39634 -61.01953 1.000 23.43286 ? 43  LEU B CB  1 
ATOM   4448 C  CG  . LEU B  1 43  ? 42.24528 -14.28329 -59.94805 1.000 28.41744 ? 43  LEU B CG  1 
ATOM   4449 C  CD1 . LEU B  1 43  ? 41.24965 -13.20169 -60.32928 1.000 26.89140 ? 43  LEU B CD1 1 
ATOM   4450 C  CD2 . LEU B  1 43  ? 41.54212 -15.61659 -59.74067 1.000 29.85056 ? 43  LEU B CD2 1 
ATOM   4451 N  N   . PRO B  1 44  ? 43.59199 -16.75935 -63.30567 1.000 23.94621 ? 44  PRO B N   1 
ATOM   4452 C  CA  . PRO B  1 44  ? 43.74907 -16.87154 -64.75566 1.000 21.16686 ? 44  PRO B CA  1 
ATOM   4453 C  C   . PRO B  1 44  ? 43.46983 -15.53538 -65.41719 1.000 23.63454 ? 44  PRO B C   1 
ATOM   4454 O  O   . PRO B  1 44  ? 42.78589 -14.68194 -64.83154 1.000 28.33585 ? 44  PRO B O   1 
ATOM   4455 C  CB  . PRO B  1 44  ? 42.69841 -17.92269 -65.14827 1.000 24.80546 ? 44  PRO B CB  1 
ATOM   4456 C  CG  . PRO B  1 44  ? 42.36944 -18.64244 -63.87444 1.000 24.89869 ? 44  PRO B CG  1 
ATOM   4457 C  CD  . PRO B  1 44  ? 42.51150 -17.61903 -62.79584 1.000 24.42357 ? 44  PRO B CD  1 
ATOM   4458 N  N   . PRO B  1 45  ? 43.99093 -15.30762 -66.62379 1.000 30.61463 ? 45  PRO B N   1 
ATOM   4459 C  CA  . PRO B  1 45  ? 43.78038 -14.01305 -67.28475 1.000 23.43060 ? 45  PRO B CA  1 
ATOM   4460 C  C   . PRO B  1 45  ? 42.30171 -13.68018 -67.42472 1.000 22.22531 ? 45  PRO B C   1 
ATOM   4461 O  O   . PRO B  1 45  ? 41.44981 -14.56153 -67.55920 1.000 24.88105 ? 45  PRO B O   1 
ATOM   4462 C  CB  . PRO B  1 45  ? 44.44663 -14.20238 -68.65153 1.000 25.77748 ? 45  PRO B CB  1 
ATOM   4463 C  CG  . PRO B  1 45  ? 45.49365 -15.24237 -68.40486 1.000 20.76939 ? 45  PRO B CG  1 
ATOM   4464 C  CD  . PRO B  1 45  ? 44.89356 -16.18138 -67.39382 1.000 21.24612 ? 45  PRO B CD  1 
ATOM   4465 N  N   . THR B  1 46  ? 42.00497 -12.38463 -67.38357 1.000 23.38746 ? 46  THR B N   1 
ATOM   4466 C  CA  . THR B  1 46  ? 40.63793 -11.88273 -67.34837 1.000 22.82900 ? 46  THR B CA  1 
ATOM   4467 C  C   . THR B  1 46  ? 40.30420 -11.18024 -68.65764 1.000 22.80939 ? 46  THR B C   1 
ATOM   4468 O  O   . THR B  1 46  ? 41.03300 -10.27916 -69.08700 1.000 17.88677 ? 46  THR B O   1 
ATOM   4469 C  CB  . THR B  1 46  ? 40.44654 -10.91912 -66.17450 1.000 20.75580 ? 46  THR B CB  1 
ATOM   4470 O  OG1 . THR B  1 46  ? 40.76348 -11.58851 -64.94756 1.000 22.68665 ? 46  THR B OG1 1 
ATOM   4471 C  CG2 . THR B  1 46  ? 39.01276 -10.42505 -66.11826 1.000 20.48663 ? 46  THR B CG2 1 
ATOM   4472 N  N   . ARG B  1 47  ? 39.20347 -11.59134 -69.28424 1.000 19.72949 ? 47  ARG B N   1 
ATOM   4473 C  CA  . ARG B  1 47  ? 38.72943 -10.91822 -70.48644 1.000 27.15592 ? 47  ARG B CA  1 
ATOM   4474 C  C   . ARG B  1 47  ? 38.28738 -9.49913  -70.14624 1.000 25.26344 ? 47  ARG B C   1 
ATOM   4475 O  O   . ARG B  1 47  ? 37.50955 -9.28713  -69.21108 1.000 23.14862 ? 47  ARG B O   1 
ATOM   4476 C  CB  . ARG B  1 47  ? 37.57844 -11.70324 -71.11573 1.000 24.35308 ? 47  ARG B CB  1 
ATOM   4477 C  CG  . ARG B  1 47  ? 36.92495 -11.00631 -72.29895 1.000 29.51847 ? 47  ARG B CG  1 
ATOM   4478 C  CD  . ARG B  1 47  ? 35.90607 -11.90153 -72.99339 1.000 36.24078 ? 47  ARG B CD  1 
ATOM   4479 N  NE  . ARG B  1 47  ? 36.53389 -13.03640 -73.66090 1.000 46.88226 ? 47  ARG B NE  1 
ATOM   4480 C  CZ  . ARG B  1 47  ? 36.49053 -14.28615 -73.21901 1.000 50.39022 ? 47  ARG B CZ  1 
ATOM   4481 N  NH1 . ARG B  1 47  ? 35.82942 -14.60819 -72.11886 1.000 47.01426 ? 47  ARG B NH1 1 
ATOM   4482 N  NH2 . ARG B  1 47  ? 37.12350 -15.23756 -73.90014 1.000 49.65829 ? 47  ARG B NH2 1 
ATOM   4483 N  N   . LEU B  1 48  ? 38.78937 -8.52408  -70.90214 1.000 25.30064 ? 48  LEU B N   1 
ATOM   4484 C  CA  . LEU B  1 48  ? 38.55117 -7.12034  -70.60254 1.000 16.81932 ? 48  LEU B CA  1 
ATOM   4485 C  C   . LEU B  1 48  ? 38.34081 -6.33869  -71.89150 1.000 20.98585 ? 48  LEU B C   1 
ATOM   4486 O  O   . LEU B  1 48  ? 38.79117 -6.73684  -72.96898 1.000 19.50126 ? 48  LEU B O   1 
ATOM   4487 C  CB  . LEU B  1 48  ? 39.72196 -6.50313  -69.82195 1.000 16.68355 ? 48  LEU B CB  1 
ATOM   4488 C  CG  . LEU B  1 48  ? 40.18177 -7.16936  -68.52449 1.000 17.53209 ? 48  LEU B CG  1 
ATOM   4489 C  CD1 . LEU B  1 48  ? 41.56596 -6.67567  -68.13942 1.000 17.03254 ? 48  LEU B CD1 1 
ATOM   4490 C  CD2 . LEU B  1 48  ? 39.19084 -6.90838  -67.40318 1.000 19.76507 ? 48  LEU B CD2 1 
ATOM   4491 N  N   . PHE B  1 49  ? 37.63763 -5.21599  -71.76232 1.000 22.96296 ? 49  PHE B N   1 
ATOM   4492 C  CA  . PHE B  1 49  ? 37.60772 -4.17348  -72.78036 1.000 18.78547 ? 49  PHE B CA  1 
ATOM   4493 C  C   . PHE B  1 49  ? 38.51818 -3.04974  -72.30459 1.000 20.07944 ? 49  PHE B C   1 
ATOM   4494 O  O   . PHE B  1 49  ? 38.30700 -2.49908  -71.21958 1.000 21.54251 ? 49  PHE B O   1 
ATOM   4495 C  CB  . PHE B  1 49  ? 36.19107 -3.64500  -73.01009 1.000 17.48999 ? 49  PHE B CB  1 
ATOM   4496 C  CG  . PHE B  1 49  ? 35.27947 -4.60782  -73.71704 1.000 18.61524 ? 49  PHE B CG  1 
ATOM   4497 C  CD1 . PHE B  1 49  ? 35.76500 -5.78779  -74.25467 1.000 21.43067 ? 49  PHE B CD1 1 
ATOM   4498 C  CD2 . PHE B  1 49  ? 33.93093 -4.31961  -73.85437 1.000 17.87050 ? 49  PHE B CD2 1 
ATOM   4499 C  CE1 . PHE B  1 49  ? 34.92017 -6.66682  -74.90797 1.000 22.82333 ? 49  PHE B CE1 1 
ATOM   4500 C  CE2 . PHE B  1 49  ? 33.08147 -5.19262  -74.50560 1.000 21.41215 ? 49  PHE B CE2 1 
ATOM   4501 C  CZ  . PHE B  1 49  ? 33.57628 -6.36819  -75.03330 1.000 24.54123 ? 49  PHE B CZ  1 
ATOM   4502 N  N   . GLY B  1 50  ? 39.52637 -2.71219  -73.10183 1.000 19.47904 ? 50  GLY B N   1 
ATOM   4503 C  CA  . GLY B  1 50  ? 40.51161 -1.74645  -72.65605 1.000 15.19929 ? 50  GLY B CA  1 
ATOM   4504 C  C   . GLY B  1 50  ? 41.04183 -0.88371  -73.77865 1.000 20.51252 ? 50  GLY B C   1 
ATOM   4505 O  O   . GLY B  1 50  ? 41.00296 -1.25333  -74.95748 1.000 18.78966 ? 50  GLY B O   1 
ATOM   4506 N  N   . TYR B  1 51  ? 41.54416 0.28481   -73.38644 1.000 18.44427 ? 51  TYR B N   1 
ATOM   4507 C  CA  . TYR B  1 51  ? 42.20131 1.18990   -74.31658 1.000 18.72925 ? 51  TYR B CA  1 
ATOM   4508 C  C   . TYR B  1 51  ? 43.61910 0.70538   -74.58939 1.000 17.98583 ? 51  TYR B C   1 
ATOM   4509 O  O   . TYR B  1 51  ? 44.36563 0.39465   -73.65600 1.000 17.38819 ? 51  TYR B O   1 
ATOM   4510 C  CB  . TYR B  1 51  ? 42.22844 2.60864   -73.75083 1.000 18.06126 ? 51  TYR B CB  1 
ATOM   4511 C  CG  . TYR B  1 51  ? 40.86307 3.18738   -73.45496 1.000 21.26656 ? 51  TYR B CG  1 
ATOM   4512 C  CD1 . TYR B  1 51  ? 40.02872 3.61181   -74.48170 1.000 16.34055 ? 51  TYR B CD1 1 
ATOM   4513 C  CD2 . TYR B  1 51  ? 40.41319 3.31924   -72.14803 1.000 16.99578 ? 51  TYR B CD2 1 
ATOM   4514 C  CE1 . TYR B  1 51  ? 38.78209 4.14449   -74.21454 1.000 17.51905 ? 51  TYR B CE1 1 
ATOM   4515 C  CE2 . TYR B  1 51  ? 39.17033 3.85242   -71.87140 1.000 16.83608 ? 51  TYR B CE2 1 
ATOM   4516 C  CZ  . TYR B  1 51  ? 38.35868 4.26280   -72.90699 1.000 20.27028 ? 51  TYR B CZ  1 
ATOM   4517 O  OH  . TYR B  1 51  ? 37.11885 4.79293   -72.63299 1.000 20.14997 ? 51  TYR B OH  1 
ATOM   4518 N  N   . ASN B  1 52  ? 43.98347 0.63654   -75.87206 1.000 19.28942 ? 52  ASN B N   1 
ATOM   4519 C  CA  . ASN B  1 52  ? 45.31236 0.18752   -76.29849 1.000 16.12455 ? 52  ASN B CA  1 
ATOM   4520 C  C   . ASN B  1 52  ? 45.67154 -1.17081  -75.70046 1.000 16.89554 ? 52  ASN B C   1 
ATOM   4521 O  O   . ASN B  1 52  ? 46.84052 -1.45830  -75.43413 1.000 21.23590 ? 52  ASN B O   1 
ATOM   4522 C  CB  . ASN B  1 52  ? 46.38340 1.22740   -75.95965 1.000 13.10411 ? 52  ASN B CB  1 
ATOM   4523 C  CG  . ASN B  1 52  ? 46.39559 2.39096   -76.93429 1.000 14.31470 ? 52  ASN B CG  1 
ATOM   4524 O  OD1 . ASN B  1 52  ? 45.49895 2.52996   -77.76645 1.000 15.37510 ? 52  ASN B OD1 1 
ATOM   4525 N  ND2 . ASN B  1 52  ? 47.41489 3.23506   -76.83396 1.000 12.08660 ? 52  ASN B ND2 1 
ATOM   4526 N  N   . GLY B  1 53  ? 44.66428 -2.01096  -75.48313 1.000 18.59872 ? 53  GLY B N   1 
ATOM   4527 C  CA  . GLY B  1 53  ? 44.89446 -3.35467  -74.97528 1.000 16.07858 ? 53  GLY B CA  1 
ATOM   4528 C  C   . GLY B  1 53  ? 45.59001 -3.41524  -73.63270 1.000 17.12237 ? 53  GLY B C   1 
ATOM   4529 O  O   . GLY B  1 53  ? 46.43506 -4.29252  -73.41484 1.000 20.76204 ? 53  GLY B O   1 
ATOM   4530 N  N   . VAL B  1 54  ? 45.25474 -2.50513  -72.72250 1.000 17.36382 ? 54  VAL B N   1 
ATOM   4531 C  CA  . VAL B  1 54  ? 45.86316 -2.48825  -71.39588 1.000 20.40943 ? 54  VAL B CA  1 
ATOM   4532 C  C   . VAL B  1 54  ? 44.83663 -1.96697  -70.39930 1.000 16.81087 ? 54  VAL B C   1 
ATOM   4533 O  O   . VAL B  1 54  ? 44.05610 -1.06152  -70.70672 1.000 17.72500 ? 54  VAL B O   1 
ATOM   4534 C  CB  . VAL B  1 54  ? 47.16139 -1.64757  -71.38062 1.000 17.05692 ? 54  VAL B CB  1 
ATOM   4535 C  CG1 . VAL B  1 54  ? 46.87904 -0.20006  -71.75605 1.000 20.54812 ? 54  VAL B CG1 1 
ATOM   4536 C  CG2 . VAL B  1 54  ? 47.84586 -1.73389  -70.02452 1.000 21.41996 ? 54  VAL B CG2 1 
ATOM   4537 N  N   . TYR B  1 55  ? 44.82885 -2.55984  -69.20678 1.000 16.23424 ? 55  TYR B N   1 
ATOM   4538 C  CA  . TYR B  1 55  ? 43.93213 -2.16051  -68.12857 1.000 19.04341 ? 55  TYR B CA  1 
ATOM   4539 C  C   . TYR B  1 55  ? 44.74842 -1.80948  -66.89170 1.000 18.00000 ? 55  TYR B C   1 
ATOM   4540 O  O   . TYR B  1 55  ? 45.44108 -2.68583  -66.34517 1.000 17.41974 ? 55  TYR B O   1 
ATOM   4541 C  CB  . TYR B  1 55  ? 42.93009 -3.27133  -67.81038 1.000 21.23954 ? 55  TYR B CB  1 
ATOM   4542 C  CG  . TYR B  1 55  ? 42.13065 -3.03578  -66.54774 1.000 21.37188 ? 55  TYR B CG  1 
ATOM   4543 C  CD1 . TYR B  1 55  ? 41.31807 -1.91734  -66.41457 1.000 22.49010 ? 55  TYR B CD1 1 
ATOM   4544 C  CD2 . TYR B  1 55  ? 42.17734 -3.94002  -65.49541 1.000 21.58511 ? 55  TYR B CD2 1 
ATOM   4545 C  CE1 . TYR B  1 55  ? 40.58196 -1.70097  -65.26383 1.000 20.83469 ? 55  TYR B CE1 1 
ATOM   4546 C  CE2 . TYR B  1 55  ? 41.44480 -3.73252  -64.34138 1.000 24.67935 ? 55  TYR B CE2 1 
ATOM   4547 C  CZ  . TYR B  1 55  ? 40.64896 -2.61251  -64.23118 1.000 21.19511 ? 55  TYR B CZ  1 
ATOM   4548 O  OH  . TYR B  1 55  ? 39.91876 -2.40430  -63.08380 1.000 18.92855 ? 55  TYR B OH  1 
ATOM   4549 N  N   . PRO B  1 56  ? 44.71310 -0.55961  -66.41146 1.000 16.05031 ? 56  PRO B N   1 
ATOM   4550 C  CA  . PRO B  1 56  ? 43.99398 0.59949   -66.96689 1.000 15.77693 ? 56  PRO B CA  1 
ATOM   4551 C  C   . PRO B  1 56  ? 44.59752 1.06782   -68.28590 1.000 17.69885 ? 56  PRO B C   1 
ATOM   4552 O  O   . PRO B  1 56  ? 45.65047 0.58593   -68.69918 1.000 16.19704 ? 56  PRO B O   1 
ATOM   4553 C  CB  . PRO B  1 56  ? 44.14370 1.66761   -65.86757 1.000 16.26021 ? 56  PRO B CB  1 
ATOM   4554 C  CG  . PRO B  1 56  ? 44.50150 0.91019   -64.61669 1.000 17.94266 ? 56  PRO B CG  1 
ATOM   4555 C  CD  . PRO B  1 56  ? 45.31928 -0.24670  -65.10744 1.000 21.15001 ? 56  PRO B CD  1 
ATOM   4556 N  N   . GLY B  1 57  ? 43.94698 2.00343   -68.97088 1.000 12.18994 ? 57  GLY B N   1 
ATOM   4557 C  CA  . GLY B  1 57  ? 44.46024 2.52503   -70.21265 1.000 14.02357 ? 57  GLY B CA  1 
ATOM   4558 C  C   . GLY B  1 57  ? 45.69435 3.37717   -70.00149 1.000 16.41794 ? 57  GLY B C   1 
ATOM   4559 O  O   . GLY B  1 57  ? 46.08547 3.67713   -68.86883 1.000 13.82748 ? 57  GLY B O   1 
ATOM   4560 N  N   . PRO B  1 58  ? 46.33846 3.77792   -71.09606 1.000 18.46586 ? 58  PRO B N   1 
ATOM   4561 C  CA  . PRO B  1 58  ? 47.51635 4.64427   -70.98375 1.000 18.10591 ? 58  PRO B CA  1 
ATOM   4562 C  C   . PRO B  1 58  ? 47.17241 5.97195   -70.32379 1.000 18.81530 ? 58  PRO B C   1 
ATOM   4563 O  O   . PRO B  1 58  ? 46.02454 6.42239   -70.32241 1.000 21.98418 ? 58  PRO B O   1 
ATOM   4564 C  CB  . PRO B  1 58  ? 47.95370 4.84209   -72.44023 1.000 19.73964 ? 58  PRO B CB  1 
ATOM   4565 C  CG  . PRO B  1 58  ? 47.36759 3.67737   -73.17530 1.000 16.29178 ? 58  PRO B CG  1 
ATOM   4566 C  CD  . PRO B  1 58  ? 46.07046 3.38080   -72.48822 1.000 14.63748 ? 58  PRO B CD  1 
ATOM   4567 N  N   . THR B  1 59  ? 48.19599 6.60226   -69.75562 1.000 16.38474 ? 59  THR B N   1 
ATOM   4568 C  CA  . THR B  1 59  ? 48.04164 7.85304   -69.02462 1.000 14.22086 ? 59  THR B CA  1 
ATOM   4569 C  C   . THR B  1 59  ? 48.43232 9.02059   -69.92290 1.000 17.96583 ? 59  THR B C   1 
ATOM   4570 O  O   . THR B  1 59  ? 49.54872 9.05693   -70.45141 1.000 21.50691 ? 59  THR B O   1 
ATOM   4571 C  CB  . THR B  1 59  ? 48.89193 7.84859   -67.75406 1.000 16.84052 ? 59  THR B CB  1 
ATOM   4572 O  OG1 . THR B  1 59  ? 48.35816 6.89890   -66.82255 1.000 18.77723 ? 59  THR B OG1 1 
ATOM   4573 C  CG2 . THR B  1 59  ? 48.90653 9.22799   -67.11545 1.000 12.13652 ? 59  THR B CG2 1 
ATOM   4574 N  N   . PHE B  1 60  ? 47.51284 9.96637   -70.09463 1.000 16.89328 ? 60  PHE B N   1 
ATOM   4575 C  CA  . PHE B  1 60  ? 47.80383 11.18901  -70.82820 1.000 12.87576 ? 60  PHE B CA  1 
ATOM   4576 C  C   . PHE B  1 60  ? 48.54657 12.17609  -69.93908 1.000 16.49474 ? 60  PHE B C   1 
ATOM   4577 O  O   . PHE B  1 60  ? 48.21333 12.34777  -68.76329 1.000 17.37924 ? 60  PHE B O   1 
ATOM   4578 C  CB  . PHE B  1 60  ? 46.51571 11.84007  -71.33033 1.000 11.82394 ? 60  PHE B CB  1 
ATOM   4579 C  CG  . PHE B  1 60  ? 45.93887 11.20426  -72.56220 1.000 12.88982 ? 60  PHE B CG  1 
ATOM   4580 C  CD1 . PHE B  1 60  ? 45.27717 9.99034   -72.49132 1.000 15.21645 ? 60  PHE B CD1 1 
ATOM   4581 C  CD2 . PHE B  1 60  ? 46.02820 11.84184  -73.78825 1.000 15.12170 ? 60  PHE B CD2 1 
ATOM   4582 C  CE1 . PHE B  1 60  ? 44.73632 9.41354   -73.62543 1.000 16.48101 ? 60  PHE B CE1 1 
ATOM   4583 C  CE2 . PHE B  1 60  ? 45.48681 11.27190  -74.92496 1.000 14.36601 ? 60  PHE B CE2 1 
ATOM   4584 C  CZ  . PHE B  1 60  ? 44.83976 10.05739  -74.84365 1.000 13.10637 ? 60  PHE B CZ  1 
ATOM   4585 N  N   . GLU B  1 61  ? 49.55232 12.83177  -70.50989 1.000 16.43618 ? 61  GLU B N   1 
ATOM   4586 C  CA  . GLU B  1 61  ? 50.25527 13.93437  -69.85770 1.000 14.51418 ? 61  GLU B CA  1 
ATOM   4587 C  C   . GLU B  1 61  ? 50.15284 15.13850  -70.78520 1.000 20.71764 ? 61  GLU B C   1 
ATOM   4588 O  O   . GLU B  1 61  ? 50.88180 15.23148  -71.77820 1.000 24.58495 ? 61  GLU B O   1 
ATOM   4589 C  CB  . GLU B  1 61  ? 51.70829 13.57716  -69.55527 1.000 13.58986 ? 61  GLU B CB  1 
ATOM   4590 C  CG  . GLU B  1 61  ? 51.89272 12.68566  -68.33746 1.000 16.36934 ? 61  GLU B CG  1 
ATOM   4591 C  CD  . GLU B  1 61  ? 51.62817 13.41039  -67.02720 1.000 19.16180 ? 61  GLU B CD  1 
ATOM   4592 O  OE1 . GLU B  1 61  ? 51.53951 14.65790  -67.03470 1.000 20.43578 ? 61  GLU B OE1 1 
ATOM   4593 O  OE2 . GLU B  1 61  ? 51.51328 12.73019  -65.98568 1.000 15.16603 ? 61  GLU B OE2 1 
ATOM   4594 N  N   . VAL B  1 62  ? 49.24190 16.05434  -70.46502 1.000 18.04239 ? 62  VAL B N   1 
ATOM   4595 C  CA  . VAL B  1 62  ? 48.98988 17.22121  -71.29538 1.000 15.97443 ? 62  VAL B CA  1 
ATOM   4596 C  C   . VAL B  1 62  ? 49.34210 18.47416  -70.50467 1.000 19.54809 ? 62  VAL B C   1 
ATOM   4597 O  O   . VAL B  1 62  ? 49.46488 18.45606  -69.27777 1.000 19.44145 ? 62  VAL B O   1 
ATOM   4598 C  CB  . VAL B  1 62  ? 47.52926 17.27793  -71.79018 1.000 17.75471 ? 62  VAL B CB  1 
ATOM   4599 C  CG1 . VAL B  1 62  ? 47.11602 15.93720  -72.37709 1.000 11.85825 ? 62  VAL B CG1 1 
ATOM   4600 C  CG2 . VAL B  1 62  ? 46.59799 17.68134  -70.66206 1.000 14.46755 ? 62  VAL B CG2 1 
ATOM   4601 N  N   . GLN B  1 63  ? 49.51026 19.57196  -71.23180 1.000 21.30427 ? 63  GLN B N   1 
ATOM   4602 C  CA  . GLN B  1 63  ? 49.85359 20.86285  -70.65994 1.000 17.88873 ? 63  GLN B CA  1 
ATOM   4603 C  C   . GLN B  1 63  ? 48.65815 21.80115  -70.75158 1.000 26.38733 ? 63  GLN B C   1 
ATOM   4604 O  O   . GLN B  1 63  ? 47.77384 21.63320  -71.59608 1.000 23.78672 ? 63  GLN B O   1 
ATOM   4605 C  CB  . GLN B  1 63  ? 51.05285 21.48114  -71.38862 1.000 18.86365 ? 63  GLN B CB  1 
ATOM   4606 C  CG  . GLN B  1 63  ? 52.14605 22.00395  -70.47539 1.000 29.85724 ? 63  GLN B CG  1 
ATOM   4607 C  CD  . GLN B  1 63  ? 52.97872 20.89029  -69.86838 1.000 38.09346 ? 63  GLN B CD  1 
ATOM   4608 O  OE1 . GLN B  1 63  ? 53.03199 19.77938  -70.39900 1.000 26.08463 ? 63  GLN B OE1 1 
ATOM   4609 N  NE2 . GLN B  1 63  ? 53.63406 21.18250  -68.74837 1.000 38.22775 ? 63  GLN B NE2 1 
ATOM   4610 N  N   . LYS B  1 64  ? 48.63511 22.79538  -69.86691 1.000 26.55496 ? 64  LYS B N   1 
ATOM   4611 C  CA  . LYS B  1 64  ? 47.65645 23.86370  -70.00104 1.000 21.02950 ? 64  LYS B CA  1 
ATOM   4612 C  C   . LYS B  1 64  ? 47.89813 24.60482  -71.30832 1.000 20.13797 ? 64  LYS B C   1 
ATOM   4613 O  O   . LYS B  1 64  ? 49.04063 24.91011  -71.66207 1.000 23.45115 ? 64  LYS B O   1 
ATOM   4614 C  CB  . LYS B  1 64  ? 47.74004 24.83078  -68.81872 1.000 18.19285 ? 64  LYS B CB  1 
ATOM   4615 C  CG  . LYS B  1 64  ? 46.63972 25.88536  -68.80313 1.000 22.95611 ? 64  LYS B CG  1 
ATOM   4616 C  CD  . LYS B  1 64  ? 46.87345 26.92164  -67.71288 1.000 23.61629 ? 64  LYS B CD  1 
ATOM   4617 C  CE  . LYS B  1 64  ? 45.69109 27.86844  -67.56137 1.000 22.22153 ? 64  LYS B CE  1 
ATOM   4618 N  NZ  . LYS B  1 64  ? 45.89985 28.83145  -66.44127 1.000 20.13351 ? 64  LYS B NZ  1 
ATOM   4619 N  N   . HIS B  1 65  ? 46.81217 24.87197  -72.03309 1.000 21.92280 ? 65  HIS B N   1 
ATOM   4620 C  CA  . HIS B  1 65  ? 46.77305 25.49618  -73.35444 1.000 21.81844 ? 65  HIS B CA  1 
ATOM   4621 C  C   . HIS B  1 65  ? 47.26148 24.56717  -74.45859 1.000 22.76760 ? 65  HIS B C   1 
ATOM   4622 O  O   . HIS B  1 65  ? 47.36856 25.00437  -75.60843 1.000 24.89483 ? 65  HIS B O   1 
ATOM   4623 C  CB  . HIS B  1 65  ? 47.57671 26.80509  -73.42454 1.000 20.33274 ? 65  HIS B CB  1 
ATOM   4624 C  CG  . HIS B  1 65  ? 47.38033 27.70350  -72.24203 1.000 22.74349 ? 65  HIS B CG  1 
ATOM   4625 N  ND1 . HIS B  1 65  ? 46.23413 28.44493  -72.04901 1.000 20.67590 ? 65  HIS B ND1 1 
ATOM   4626 C  CD2 . HIS B  1 65  ? 48.19067 27.98487  -71.19421 1.000 16.71877 ? 65  HIS B CD2 1 
ATOM   4627 C  CE1 . HIS B  1 65  ? 46.34432 29.13873  -70.92997 1.000 18.91194 ? 65  HIS B CE1 1 
ATOM   4628 N  NE2 . HIS B  1 65  ? 47.52239 28.87790  -70.39252 1.000 18.86333 ? 65  HIS B NE2 1 
ATOM   4629 N  N   . GLU B  1 66  ? 47.56237 23.30604  -74.15680 1.000 20.38373 ? 66  GLU B N   1 
ATOM   4630 C  CA  . GLU B  1 66  ? 47.99955 22.35836  -75.17723 1.000 15.43509 ? 66  GLU B CA  1 
ATOM   4631 C  C   . GLU B  1 66  ? 46.77265 21.80073  -75.88931 1.000 17.18160 ? 66  GLU B C   1 
ATOM   4632 O  O   . GLU B  1 66  ? 45.95892 21.09580  -75.28336 1.000 21.71534 ? 66  GLU B O   1 
ATOM   4633 C  CB  . GLU B  1 66  ? 48.83292 21.23770  -74.55920 1.000 13.69694 ? 66  GLU B CB  1 
ATOM   4634 C  CG  . GLU B  1 66  ? 49.31467 20.20215  -75.56536 1.000 12.81515 ? 66  GLU B CG  1 
ATOM   4635 C  CD  . GLU B  1 66  ? 50.10430 19.07467  -74.92615 1.000 19.19363 ? 66  GLU B CD  1 
ATOM   4636 O  OE1 . GLU B  1 66  ? 50.37773 19.14447  -73.70925 1.000 15.56564 ? 66  GLU B OE1 1 
ATOM   4637 O  OE2 . GLU B  1 66  ? 50.45124 18.11427  -75.64563 1.000 19.73820 ? 66  GLU B OE2 1 
ATOM   4638 N  N   . LYS B  1 67  ? 46.63600 22.11737  -77.17351 1.000 17.25220 ? 67  LYS B N   1 
ATOM   4639 C  CA  . LYS B  1 67  ? 45.52767 21.62016  -77.98588 1.000 16.96966 ? 67  LYS B CA  1 
ATOM   4640 C  C   . LYS B  1 67  ? 45.76146 20.14276  -78.27834 1.000 21.37985 ? 67  LYS B C   1 
ATOM   4641 O  O   . LYS B  1 67  ? 46.56976 19.78718  -79.13845 1.000 24.72174 ? 67  LYS B O   1 
ATOM   4642 C  CB  . LYS B  1 67  ? 45.41420 22.42659  -79.27452 1.000 22.48844 ? 67  LYS B CB  1 
ATOM   4643 C  CG  . LYS B  1 67  ? 43.99215 22.80703  -79.65624 1.000 39.91249 ? 67  LYS B CG  1 
ATOM   4644 C  CD  . LYS B  1 67  ? 43.88174 23.07157  -81.15206 1.000 47.89425 ? 67  LYS B CD  1 
ATOM   4645 C  CE  . LYS B  1 67  ? 42.47762 23.50844  -81.54634 1.000 55.08640 ? 67  LYS B CE  1 
ATOM   4646 N  NZ  . LYS B  1 67  ? 42.19947 24.91978  -81.15625 1.000 51.26762 ? 67  LYS B NZ  1 
ATOM   4647 N  N   . VAL B  1 68  ? 45.05195 19.27185  -77.56410 1.000 14.58778 ? 68  VAL B N   1 
ATOM   4648 C  CA  . VAL B  1 68  ? 45.23404 17.82820  -77.66869 1.000 14.96009 ? 68  VAL B CA  1 
ATOM   4649 C  C   . VAL B  1 68  ? 44.08016 17.23666  -78.46492 1.000 18.53309 ? 68  VAL B C   1 
ATOM   4650 O  O   . VAL B  1 68  ? 42.90853 17.51980  -78.18279 1.000 19.60127 ? 68  VAL B O   1 
ATOM   4651 C  CB  . VAL B  1 68  ? 45.33315 17.17946  -76.27763 1.000 18.47037 ? 68  VAL B CB  1 
ATOM   4652 C  CG1 . VAL B  1 68  ? 45.29786 15.66317  -76.39210 1.000 15.75143 ? 68  VAL B CG1 1 
ATOM   4653 C  CG2 . VAL B  1 68  ? 46.60421 17.63229  -75.57744 1.000 15.94836 ? 68  VAL B CG2 1 
ATOM   4654 N  N   . ALA B  1 69  ? 44.40921 16.41139  -79.45660 1.000 18.91015 ? 69  ALA B N   1 
ATOM   4655 C  CA  . ALA B  1 69  ? 43.42267 15.73305  -80.28525 1.000 16.79467 ? 69  ALA B CA  1 
ATOM   4656 C  C   . ALA B  1 69  ? 43.57903 14.22926  -80.12369 1.000 16.44926 ? 69  ALA B C   1 
ATOM   4657 O  O   . ALA B  1 69  ? 44.69556 13.70551  -80.19785 1.000 21.45525 ? 69  ALA B O   1 
ATOM   4658 C  CB  . ALA B  1 69  ? 43.56808 16.12400  -81.75713 1.000 16.72926 ? 69  ALA B CB  1 
ATOM   4659 N  N   . VAL B  1 70  ? 42.46269 13.54021  -79.89894 1.000 17.44114 ? 70  VAL B N   1 
ATOM   4660 C  CA  . VAL B  1 70  ? 42.44655 12.09282  -79.72587 1.000 14.71488 ? 70  VAL B CA  1 
ATOM   4661 C  C   . VAL B  1 70  ? 41.39888 11.51139  -80.66144 1.000 15.79983 ? 70  VAL B C   1 
ATOM   4662 O  O   . VAL B  1 70  ? 40.27939 12.02830  -80.74246 1.000 19.50565 ? 70  VAL B O   1 
ATOM   4663 C  CB  . VAL B  1 70  ? 42.14313 11.68468  -78.27107 1.000 13.76685 ? 70  VAL B CB  1 
ATOM   4664 C  CG1 . VAL B  1 70  ? 42.36961 10.19145  -78.08848 1.000 15.75294 ? 70  VAL B CG1 1 
ATOM   4665 C  CG2 . VAL B  1 70  ? 42.99085 12.48662  -77.29258 1.000 14.15471 ? 70  VAL B CG2 1 
ATOM   4666 N  N   . LYS B  1 71  ? 41.75844 10.44116  -81.36176 1.000 17.19187 ? 71  LYS B N   1 
ATOM   4667 C  CA  . LYS B  1 71  ? 40.83750 9.71313   -82.22981 1.000 17.04433 ? 71  LYS B CA  1 
ATOM   4668 C  C   . LYS B  1 71  ? 40.56401 8.36560   -81.56737 1.000 16.14583 ? 71  LYS B C   1 
ATOM   4669 O  O   . LYS B  1 71  ? 41.31409 7.40463   -81.74511 1.000 19.50810 ? 71  LYS B O   1 
ATOM   4670 C  CB  . LYS B  1 71  ? 41.40887 9.54742   -83.63580 1.000 19.33086 ? 71  LYS B CB  1 
ATOM   4671 C  CG  . LYS B  1 71  ? 40.45017 8.88078   -84.61089 1.000 17.30040 ? 71  LYS B CG  1 
ATOM   4672 C  CD  . LYS B  1 71  ? 40.98593 8.92082   -86.03020 1.000 18.22746 ? 71  LYS B CD  1 
ATOM   4673 C  CE  . LYS B  1 71  ? 39.97605 8.36108   -87.01611 1.000 15.11959 ? 71  LYS B CE  1 
ATOM   4674 N  NZ  . LYS B  1 71  ? 40.47434 8.43227   -88.41647 1.000 16.59133 ? 71  LYS B NZ  1 
ATOM   4675 N  N   . TRP B  1 72  ? 39.48287 8.30543   -80.79367 1.000 18.98551 ? 72  TRP B N   1 
ATOM   4676 C  CA  . TRP B  1 72  ? 39.11350 7.08217   -80.08923 1.000 18.49004 ? 72  TRP B CA  1 
ATOM   4677 C  C   . TRP B  1 72  ? 38.55443 6.07719   -81.08825 1.000 18.37425 ? 72  TRP B C   1 
ATOM   4678 O  O   . TRP B  1 72  ? 37.49673 6.30379   -81.68337 1.000 23.12948 ? 72  TRP B O   1 
ATOM   4679 C  CB  . TRP B  1 72  ? 38.09633 7.38829   -78.99469 1.000 13.14415 ? 72  TRP B CB  1 
ATOM   4680 C  CG  . TRP B  1 72  ? 38.45130 8.56858   -78.14214 1.000 11.59563 ? 72  TRP B CG  1 
ATOM   4681 C  CD1 . TRP B  1 72  ? 38.01207 9.85014   -78.29698 1.000 12.50530 ? 72  TRP B CD1 1 
ATOM   4682 C  CD2 . TRP B  1 72  ? 39.31558 8.57631   -76.99909 1.000 12.19526 ? 72  TRP B CD2 1 
ATOM   4683 N  NE1 . TRP B  1 72  ? 38.54704 10.65550  -77.32200 1.000 13.45380 ? 72  TRP B NE1 1 
ATOM   4684 C  CE2 . TRP B  1 72  ? 39.35061 9.89748   -76.51184 1.000 13.34235 ? 72  TRP B CE2 1 
ATOM   4685 C  CE3 . TRP B  1 72  ? 40.06149 7.59423   -76.33949 1.000 12.93384 ? 72  TRP B CE3 1 
ATOM   4686 C  CZ2 . TRP B  1 72  ? 40.10482 10.26291  -75.39831 1.000 13.98927 ? 72  TRP B CZ2 1 
ATOM   4687 C  CZ3 . TRP B  1 72  ? 40.80814 7.95857   -75.23394 1.000 11.09937 ? 72  TRP B CZ3 1 
ATOM   4688 C  CH2 . TRP B  1 72  ? 40.82429 9.28086   -74.77465 1.000 12.24893 ? 72  TRP B CH2 1 
ATOM   4689 N  N   . LEU B  1 73  ? 39.25885 4.96659   -81.27263 1.000 18.55858 ? 73  LEU B N   1 
ATOM   4690 C  CA  . LEU B  1 73  ? 38.88275 3.95131   -82.24407 1.000 17.46984 ? 73  LEU B CA  1 
ATOM   4691 C  C   . LEU B  1 73  ? 38.25438 2.75602   -81.54158 1.000 22.08297 ? 73  LEU B C   1 
ATOM   4692 O  O   . LEU B  1 73  ? 38.74864 2.29863   -80.50655 1.000 21.08234 ? 73  LEU B O   1 
ATOM   4693 C  CB  . LEU B  1 73  ? 40.10058 3.50213   -83.05318 1.000 23.59636 ? 73  LEU B CB  1 
ATOM   4694 C  CG  . LEU B  1 73  ? 40.83207 4.61404   -83.80818 1.000 22.96271 ? 73  LEU B CG  1 
ATOM   4695 C  CD1 . LEU B  1 73  ? 42.14374 4.10612   -84.38816 1.000 18.86108 ? 73  LEU B CD1 1 
ATOM   4696 C  CD2 . LEU B  1 73  ? 39.94300 5.18512   -84.90253 1.000 21.60645 ? 73  LEU B CD2 1 
ATOM   4697 N  N   . ASN B  1 74  ? 37.16046 2.25535   -82.11168 1.000 19.53397 ? 74  ASN B N   1 
ATOM   4698 C  CA  . ASN B  1 74  ? 36.45287 1.09478   -81.58393 1.000 16.68862 ? 74  ASN B CA  1 
ATOM   4699 C  C   . ASN B  1 74  ? 36.88942 -0.13111  -82.37881 1.000 21.03247 ? 74  ASN B C   1 
ATOM   4700 O  O   . ASN B  1 74  ? 36.59004 -0.24644  -83.57159 1.000 22.92659 ? 74  ASN B O   1 
ATOM   4701 C  CB  . ASN B  1 74  ? 34.93980 1.29987   -81.66088 1.000 17.36470 ? 74  ASN B CB  1 
ATOM   4702 C  CG  . ASN B  1 74  ? 34.15169 0.19042   -80.96863 1.000 21.14561 ? 74  ASN B CG  1 
ATOM   4703 O  OD1 . ASN B  1 74  ? 34.53108 -0.98074  -81.00227 1.000 21.92685 ? 74  ASN B OD1 1 
ATOM   4704 N  ND2 . ASN B  1 74  ? 33.04150 0.56203   -80.34107 1.000 13.48172 ? 74  ASN B ND2 1 
ATOM   4705 N  N   . LYS B  1 75  ? 37.60268 -1.04026  -81.71618 1.000 20.51042 ? 75  LYS B N   1 
ATOM   4706 C  CA  . LYS B  1 75  ? 37.97133 -2.33127  -82.28407 1.000 21.00876 ? 75  LYS B CA  1 
ATOM   4707 C  C   . LYS B  1 75  ? 37.39436 -3.47084  -81.45221 1.000 19.38095 ? 75  LYS B C   1 
ATOM   4708 O  O   . LYS B  1 75  ? 37.95041 -4.56984  -81.41420 1.000 21.81589 ? 75  LYS B O   1 
ATOM   4709 C  CB  . LYS B  1 75  ? 39.48936 -2.46400  -82.39896 1.000 22.01841 ? 75  LYS B CB  1 
ATOM   4710 C  CG  . LYS B  1 75  ? 40.12095 -1.54050  -83.42572 1.000 22.05028 ? 75  LYS B CG  1 
ATOM   4711 C  CD  . LYS B  1 75  ? 39.63726 -1.86524  -84.82910 1.000 28.22110 ? 75  LYS B CD  1 
ATOM   4712 C  CE  . LYS B  1 75  ? 40.35121 -1.01778  -85.86934 1.000 30.03753 ? 75  LYS B CE  1 
ATOM   4713 N  NZ  . LYS B  1 75  ? 39.93137 -1.36920  -87.25376 1.000 33.84619 ? 75  LYS B NZ  1 
ATOM   4714 N  N   . LEU B  1 76  ? 36.27738 -3.21320  -80.78141 1.000 19.91146 ? 76  LEU B N   1 
ATOM   4715 C  CA  . LEU B  1 76  ? 35.67964 -4.16914  -79.86769 1.000 16.86224 ? 76  LEU B CA  1 
ATOM   4716 C  C   . LEU B  1 76  ? 34.81845 -5.17758  -80.62154 1.000 21.37942 ? 76  LEU B C   1 
ATOM   4717 O  O   . LEU B  1 76  ? 34.38021 -4.91942  -81.74537 1.000 28.85931 ? 76  LEU B O   1 
ATOM   4718 C  CB  . LEU B  1 76  ? 34.85142 -3.43060  -78.82009 1.000 21.55124 ? 76  LEU B CB  1 
ATOM   4719 C  CG  . LEU B  1 76  ? 35.69124 -2.60106  -77.84681 1.000 26.93856 ? 76  LEU B CG  1 
ATOM   4720 C  CD1 . LEU B  1 76  ? 34.81770 -1.90252  -76.81924 1.000 23.23088 ? 76  LEU B CD1 1 
ATOM   4721 C  CD2 . LEU B  1 76  ? 36.72703 -3.48330  -77.16430 1.000 18.81398 ? 76  LEU B CD2 1 
ATOM   4722 N  N   . PRO B  1 77  ? 34.56760 -6.35060  -80.02279 1.000 23.04561 ? 77  PRO B N   1 
ATOM   4723 C  CA  . PRO B  1 77  ? 33.77513 -7.37714  -80.71434 1.000 22.44967 ? 77  PRO B CA  1 
ATOM   4724 C  C   . PRO B  1 77  ? 32.33981 -6.95788  -80.98855 1.000 27.86077 ? 77  PRO B C   1 
ATOM   4725 O  O   . PRO B  1 77  ? 31.89595 -5.87789  -80.58544 1.000 17.68884 ? 77  PRO B O   1 
ATOM   4726 C  CB  . PRO B  1 77  ? 33.82083 -8.56752  -79.74633 1.000 19.16757 ? 77  PRO B CB  1 
ATOM   4727 C  CG  . PRO B  1 77  ? 35.01426 -8.32834  -78.89828 1.000 24.33550 ? 77  PRO B CG  1 
ATOM   4728 C  CD  . PRO B  1 77  ? 35.11683 -6.84792  -78.74970 1.000 24.82802 ? 77  PRO B CD  1 
ATOM   4729 N  N   . ASP B  1 78  ? 31.60716 -7.82917  -81.68086 1.000 28.65593 ? 78  ASP B N   1 
ATOM   4730 C  CA  . ASP B  1 78  ? 30.19986 -7.59892  -81.97323 1.000 32.46690 ? 78  ASP B CA  1 
ATOM   4731 C  C   . ASP B  1 78  ? 29.30100 -7.84417  -80.76921 1.000 33.21534 ? 78  ASP B C   1 
ATOM   4732 O  O   . ASP B  1 78  ? 28.15106 -7.39219  -80.76769 1.000 35.09661 ? 78  ASP B O   1 
ATOM   4733 C  CB  . ASP B  1 78  ? 29.76451 -8.50277  -83.12866 1.000 48.40364 ? 78  ASP B CB  1 
ATOM   4734 C  CG  . ASP B  1 78  ? 30.14220 -9.95921  -82.90033 1.000 48.45223 ? 78  ASP B CG  1 
ATOM   4735 O  OD1 . ASP B  1 78  ? 29.42493 -10.65200 -82.14764 1.000 41.49976 ? 78  ASP B OD1 1 
ATOM   4736 O  OD2 . ASP B  1 78  ? 31.16379 -10.40819 -83.46356 1.000 48.59083 ? 78  ASP B OD2 1 
ATOM   4737 N  N   . HIS B  1 79  ? 29.80002 -8.53778  -79.74961 1.000 34.01830 ? 79  HIS B N   1 
ATOM   4738 C  CA  . HIS B  1 79  ? 28.99680 -9.00099  -78.62844 1.000 31.85998 ? 79  HIS B CA  1 
ATOM   4739 C  C   . HIS B  1 79  ? 29.69875 -8.64863  -77.32502 1.000 33.92610 ? 79  HIS B C   1 
ATOM   4740 O  O   . HIS B  1 79  ? 30.92098 -8.78486  -77.21273 1.000 34.59265 ? 79  HIS B O   1 
ATOM   4741 C  CB  . HIS B  1 79  ? 28.76569 -10.51941 -78.73040 1.000 34.15950 ? 79  HIS B CB  1 
ATOM   4742 C  CG  . HIS B  1 79  ? 28.00819 -11.10573 -77.57963 1.000 43.51574 ? 79  HIS B CG  1 
ATOM   4743 N  ND1 . HIS B  1 79  ? 26.65704 -11.37367 -77.63603 1.000 43.65787 ? 79  HIS B ND1 1 
ATOM   4744 C  CD2 . HIS B  1 79  ? 28.41761 -11.49604 -76.34925 1.000 40.04706 ? 79  HIS B CD2 1 
ATOM   4745 C  CE1 . HIS B  1 79  ? 26.26490 -11.89381 -76.48654 1.000 38.66428 ? 79  HIS B CE1 1 
ATOM   4746 N  NE2 . HIS B  1 79  ? 27.31375 -11.97748 -75.68782 1.000 38.68857 ? 79  HIS B NE2 1 
ATOM   4747 N  N   . HIS B  1 80  ? 28.92283 -8.19174  -76.34458 1.000 24.91038 ? 80  HIS B N   1 
ATOM   4748 C  CA  . HIS B  1 80  ? 29.45881 -7.80185  -75.04691 1.000 23.21077 ? 80  HIS B CA  1 
ATOM   4749 C  C   . HIS B  1 80  ? 29.45171 -9.00201  -74.10835 1.000 19.96672 ? 80  HIS B C   1 
ATOM   4750 O  O   . HIS B  1 80  ? 28.44511 -9.70913  -74.00435 1.000 27.12351 ? 80  HIS B O   1 
ATOM   4751 C  CB  . HIS B  1 80  ? 28.64024 -6.65582  -74.44963 1.000 24.08779 ? 80  HIS B CB  1 
ATOM   4752 C  CG  . HIS B  1 80  ? 29.41543 -5.77846  -73.51575 1.000 21.30157 ? 80  HIS B CG  1 
ATOM   4753 N  ND1 . HIS B  1 80  ? 30.20422 -6.28028  -72.50309 1.000 20.79364 ? 80  HIS B ND1 1 
ATOM   4754 C  CD2 . HIS B  1 80  ? 29.51756 -4.43005  -73.43862 1.000 16.56831 ? 80  HIS B CD2 1 
ATOM   4755 C  CE1 . HIS B  1 80  ? 30.76189 -5.27950  -71.84480 1.000 19.74853 ? 80  HIS B CE1 1 
ATOM   4756 N  NE2 . HIS B  1 80  ? 30.36093 -4.14605  -72.39189 1.000 15.57686 ? 80  HIS B NE2 1 
ATOM   4757 N  N   . PHE B  1 81  ? 30.57201 -9.22493  -73.42017 1.000 19.06403 ? 81  PHE B N   1 
ATOM   4758 C  CA  . PHE B  1 81  ? 30.68731 -10.37198 -72.52815 1.000 18.46095 ? 81  PHE B CA  1 
ATOM   4759 C  C   . PHE B  1 81  ? 30.00416 -10.15869 -71.18247 1.000 22.63732 ? 81  PHE B C   1 
ATOM   4760 O  O   . PHE B  1 81  ? 29.86612 -11.12094 -70.41962 1.000 20.04880 ? 81  PHE B O   1 
ATOM   4761 C  CB  . PHE B  1 81  ? 32.16167 -10.72851 -72.31107 1.000 19.27152 ? 81  PHE B CB  1 
ATOM   4762 C  CG  . PHE B  1 81  ? 32.95265 -9.66715  -71.59914 1.000 20.13519 ? 81  PHE B CG  1 
ATOM   4763 C  CD1 . PHE B  1 81  ? 33.48276 -8.59272  -72.29449 1.000 18.52452 ? 81  PHE B CD1 1 
ATOM   4764 C  CD2 . PHE B  1 81  ? 33.18579 -9.75707  -70.23596 1.000 21.89808 ? 81  PHE B CD2 1 
ATOM   4765 C  CE1 . PHE B  1 81  ? 34.21957 -7.62037  -71.64083 1.000 20.24531 ? 81  PHE B CE1 1 
ATOM   4766 C  CE2 . PHE B  1 81  ? 33.92091 -8.78931  -69.57786 1.000 20.54238 ? 81  PHE B CE2 1 
ATOM   4767 C  CZ  . PHE B  1 81  ? 34.43890 -7.71987  -70.28135 1.000 19.89236 ? 81  PHE B CZ  1 
ATOM   4768 N  N   . LEU B  1 82  ? 29.57763 -8.93036  -70.86948 1.000 21.34602 ? 82  LEU B N   1 
ATOM   4769 C  CA  . LEU B  1 82  ? 28.83371 -8.66576  -69.64976 1.000 19.47607 ? 82  LEU B CA  1 
ATOM   4770 C  C   . LEU B  1 82  ? 27.33690 -8.62779  -69.94066 1.000 18.66273 ? 82  LEU B C   1 
ATOM   4771 O  O   . LEU B  1 82  ? 26.92459 -8.26657  -71.04700 1.000 22.71889 ? 82  LEU B O   1 
ATOM   4772 C  CB  . LEU B  1 82  ? 29.27469 -7.33752  -69.02554 1.000 23.88595 ? 82  LEU B CB  1 
ATOM   4773 C  CG  . LEU B  1 82  ? 30.71676 -7.29048  -68.51137 1.000 18.83531 ? 82  LEU B CG  1 
ATOM   4774 C  CD1 . LEU B  1 82  ? 31.03823 -5.92386  -67.93028 1.000 18.32006 ? 82  LEU B CD1 1 
ATOM   4775 C  CD2 . LEU B  1 82  ? 30.95619 -8.37971  -67.47737 1.000 15.02397 ? 82  LEU B CD2 1 
ATOM   4776 N  N   . PRO B  1 83  ? 26.49556 -9.00228  -68.97435 1.000 16.77751 ? 83  PRO B N   1 
ATOM   4777 C  CA  . PRO B  1 83  ? 25.04892 -9.09732  -69.23820 1.000 15.94824 ? 83  PRO B CA  1 
ATOM   4778 C  C   . PRO B  1 83  ? 24.44901 -7.73277  -69.54708 1.000 21.60549 ? 83  PRO B C   1 
ATOM   4779 O  O   . PRO B  1 83  ? 24.55765 -6.79622  -68.75284 1.000 23.37195 ? 83  PRO B O   1 
ATOM   4780 C  CB  . PRO B  1 83  ? 24.48869 -9.68320  -67.93687 1.000 22.57280 ? 83  PRO B CB  1 
ATOM   4781 C  CG  . PRO B  1 83  ? 25.50567 -9.34290  -66.89758 1.000 21.90984 ? 83  PRO B CG  1 
ATOM   4782 C  CD  . PRO B  1 83  ? 26.83113 -9.39385  -67.59468 1.000 19.01716 ? 83  PRO B CD  1 
ATOM   4783 N  N   . VAL B  1 84  ? 23.80408 -7.63124  -70.70698 1.000 19.21128 ? 84  VAL B N   1 
ATOM   4784 C  CA  . VAL B  1 84  ? 23.23286 -6.38196  -71.19670 1.000 17.85698 ? 84  VAL B CA  1 
ATOM   4785 C  C   . VAL B  1 84  ? 21.72349 -6.41717  -71.00179 1.000 26.30530 ? 84  VAL B C   1 
ATOM   4786 O  O   . VAL B  1 84  ? 21.05533 -7.36793  -71.42833 1.000 27.04604 ? 84  VAL B O   1 
ATOM   4787 C  CB  . VAL B  1 84  ? 23.58842 -6.15480  -72.67607 1.000 17.68553 ? 84  VAL B CB  1 
ATOM   4788 C  CG1 . VAL B  1 84  ? 22.86578 -4.92960  -73.21817 1.000 19.92488 ? 84  VAL B CG1 1 
ATOM   4789 C  CG2 . VAL B  1 84  ? 25.09203 -6.01467  -72.84343 1.000 14.95570 ? 84  VAL B CG2 1 
ATOM   4790 N  N   . ASP B  1 85  ? 21.18482 -5.38207  -70.36046 1.000 24.30394 ? 85  ASP B N   1 
ATOM   4791 C  CA  . ASP B  1 85  ? 19.74326 -5.22964  -70.19179 1.000 23.48251 ? 85  ASP B CA  1 
ATOM   4792 C  C   . ASP B  1 85  ? 19.19434 -4.52285  -71.42609 1.000 26.34842 ? 85  ASP B C   1 
ATOM   4793 O  O   . ASP B  1 85  ? 19.50178 -3.35105  -71.66794 1.000 28.34928 ? 85  ASP B O   1 
ATOM   4794 C  CB  . ASP B  1 85  ? 19.42734 -4.45010  -68.91660 1.000 24.25474 ? 85  ASP B CB  1 
ATOM   4795 C  CG  . ASP B  1 85  ? 17.94256 -4.45860  -68.56772 1.000 30.38624 ? 85  ASP B CG  1 
ATOM   4796 O  OD1 . ASP B  1 85  ? 17.09556 -4.38726  -69.48454 1.000 27.25638 ? 85  ASP B OD1 1 
ATOM   4797 O  OD2 . ASP B  1 85  ? 17.62059 -4.53303  -67.36356 1.000 26.81254 ? 85  ASP B OD2 1 
ATOM   4798 N  N   . HIS B  1 86  ? 18.37664 -5.23118  -72.20084 1.000 29.52275 ? 86  HIS B N   1 
ATOM   4799 C  CA  . HIS B  1 86  ? 17.80203 -4.69744  -73.42794 1.000 33.59084 ? 86  HIS B CA  1 
ATOM   4800 C  C   . HIS B  1 86  ? 16.46772 -3.99538  -73.20309 1.000 34.51561 ? 86  HIS B C   1 
ATOM   4801 O  O   . HIS B  1 86  ? 15.76996 -3.69497  -74.17728 1.000 36.89178 ? 86  HIS B O   1 
ATOM   4802 C  CB  . HIS B  1 86  ? 17.62234 -5.81815  -74.45680 1.000 26.54340 ? 86  HIS B CB  1 
ATOM   4803 C  CG  . HIS B  1 86  ? 18.85317 -6.64144  -74.67864 1.000 29.96330 ? 86  HIS B CG  1 
ATOM   4804 N  ND1 . HIS B  1 86  ? 19.81254 -6.31116  -75.61174 1.000 21.94814 ? 86  HIS B ND1 1 
ATOM   4805 C  CD2 . HIS B  1 86  ? 19.27778 -7.78574  -74.09168 1.000 26.75194 ? 86  HIS B CD2 1 
ATOM   4806 C  CE1 . HIS B  1 86  ? 20.77630 -7.21452  -75.58803 1.000 22.94851 ? 86  HIS B CE1 1 
ATOM   4807 N  NE2 . HIS B  1 86  ? 20.47621 -8.12010  -74.67435 1.000 27.24597 ? 86  HIS B NE2 1 
ATOM   4808 N  N   . THR B  1 87  ? 16.09660 -3.72628  -71.95061 1.000 32.63419 ? 87  THR B N   1 
ATOM   4809 C  CA  . THR B  1 87  ? 14.79139 -3.16099  -71.64019 1.000 31.22588 ? 87  THR B CA  1 
ATOM   4810 C  C   . THR B  1 87  ? 14.85444 -1.77574  -71.01297 1.000 34.84417 ? 87  THR B C   1 
ATOM   4811 O  O   . THR B  1 87  ? 13.80019 -1.16625  -70.79846 1.000 34.72020 ? 87  THR B O   1 
ATOM   4812 C  CB  . THR B  1 87  ? 14.01308 -4.09396  -70.70032 1.000 28.80389 ? 87  THR B CB  1 
ATOM   4813 O  OG1 . THR B  1 87  ? 14.55107 -3.99781  -69.37519 1.000 32.96782 ? 87  THR B OG1 1 
ATOM   4814 C  CG2 . THR B  1 87  ? 14.11153 -5.53580  -71.17503 1.000 29.19319 ? 87  THR B CG2 1 
ATOM   4815 N  N   . ILE B  1 88  ? 16.04299 -1.25840  -70.71090 1.000 35.16919 ? 88  ILE B N   1 
ATOM   4816 C  CA  . ILE B  1 88  ? 16.12807 0.02024   -70.01418 1.000 36.81191 ? 88  ILE B CA  1 
ATOM   4817 C  C   . ILE B  1 88  ? 16.14475 1.20626   -70.97670 1.000 37.85073 ? 88  ILE B C   1 
ATOM   4818 O  O   . ILE B  1 88  ? 15.66296 2.28841   -70.62618 1.000 47.76994 ? 88  ILE B O   1 
ATOM   4819 C  CB  . ILE B  1 88  ? 17.35232 0.04565   -69.08255 1.000 31.23029 ? 88  ILE B CB  1 
ATOM   4820 C  CG1 . ILE B  1 88  ? 18.63835 -0.23292  -69.86120 1.000 28.43075 ? 88  ILE B CG1 1 
ATOM   4821 C  CG2 . ILE B  1 88  ? 17.18007 -0.96265  -67.95582 1.000 30.04744 ? 88  ILE B CG2 1 
ATOM   4822 C  CD1 . ILE B  1 88  ? 19.88586 -0.17982  -69.00371 1.000 20.05234 ? 88  ILE B CD1 1 
ATOM   4823 N  N   . HIS B  1 89  ? 16.68156 1.03263   -72.18015 1.000 33.88541 ? 89  HIS B N   1 
ATOM   4824 C  CA  . HIS B  1 89  ? 16.67970 2.10102   -73.17500 1.000 36.36764 ? 89  HIS B CA  1 
ATOM   4825 C  C   . HIS B  1 89  ? 16.58663 1.54109   -74.58971 1.000 43.27178 ? 89  HIS B C   1 
ATOM   4826 O  O   . HIS B  1 89  ? 15.60968 1.78367   -75.29959 1.000 39.14256 ? 89  HIS B O   1 
ATOM   4827 C  CB  . HIS B  1 89  ? 17.93007 2.97314   -73.03693 1.000 35.71056 ? 89  HIS B CB  1 
ATOM   4828 C  CG  . HIS B  1 89  ? 17.79714 4.06405   -72.01995 1.000 42.13532 ? 89  HIS B CG  1 
ATOM   4829 N  ND1 . HIS B  1 89  ? 16.84259 5.05407   -72.11292 1.000 49.80962 ? 89  HIS B ND1 1 
ATOM   4830 C  CD2 . HIS B  1 89  ? 18.50216 4.32614   -70.89370 1.000 39.85779 ? 89  HIS B CD2 1 
ATOM   4831 C  CE1 . HIS B  1 89  ? 16.96116 5.87547   -71.08496 1.000 51.12993 ? 89  HIS B CE1 1 
ATOM   4832 N  NE2 . HIS B  1 89  ? 17.96148 5.45675   -70.33054 1.000 42.18666 ? 89  HIS B NE2 1 
ATOM   4833 N  N   . GLU B  1 97  ? 24.47877 -4.76016  -78.19049 1.000 35.96061 ? 97  GLU B N   1 
ATOM   4834 C  CA  . GLU B  1 97  ? 25.70125 -4.51888  -78.94830 1.000 40.30392 ? 97  GLU B CA  1 
ATOM   4835 C  C   . GLU B  1 97  ? 26.72557 -3.76599  -78.10666 1.000 39.43221 ? 97  GLU B C   1 
ATOM   4836 O  O   . GLU B  1 97  ? 26.43942 -3.36409  -76.97840 1.000 28.32832 ? 97  GLU B O   1 
ATOM   4837 C  CB  . GLU B  1 97  ? 25.39217 -3.74446  -80.23334 1.000 40.61517 ? 97  GLU B CB  1 
ATOM   4838 C  CG  . GLU B  1 97  ? 24.68632 -4.57718  -81.29523 1.000 51.48117 ? 97  GLU B CG  1 
ATOM   4839 C  CD  . GLU B  1 97  ? 23.37442 -3.96523  -81.75100 1.000 55.11265 ? 97  GLU B CD  1 
ATOM   4840 O  OE1 . GLU B  1 97  ? 23.23575 -2.72590  -81.68237 1.000 51.09611 ? 97  GLU B OE1 1 
ATOM   4841 O  OE2 . GLU B  1 97  ? 22.47891 -4.72686  -82.17455 1.000 50.11710 ? 97  GLU B OE2 1 
ATOM   4842 N  N   . VAL B  1 98  ? 27.91918 -3.57937  -78.66008 1.000 40.90218 ? 98  VAL B N   1 
ATOM   4843 C  CA  . VAL B  1 98  ? 29.01147 -2.90535  -77.96126 1.000 33.88248 ? 98  VAL B CA  1 
ATOM   4844 C  C   . VAL B  1 98  ? 29.09551 -1.49380  -78.53365 1.000 28.90170 ? 98  VAL B C   1 
ATOM   4845 O  O   . VAL B  1 98  ? 29.75681 -1.24023  -79.54175 1.000 25.56095 ? 98  VAL B O   1 
ATOM   4846 C  CB  . VAL B  1 98  ? 30.32997 -3.66455  -78.09279 1.000 28.52008 ? 98  VAL B CB  1 
ATOM   4847 C  CG1 . VAL B  1 98  ? 31.43121 -2.93467  -77.34398 1.000 22.84873 ? 98  VAL B CG1 1 
ATOM   4848 C  CG2 . VAL B  1 98  ? 30.17793 -5.08255  -77.56412 1.000 23.97770 ? 98  VAL B CG2 1 
ATOM   4849 N  N   . LYS B  1 99  ? 28.41091 -0.56283  -77.87836 1.000 30.01803 ? 99  LYS B N   1 
ATOM   4850 C  CA  . LYS B  1 99  ? 28.46244 0.84957   -78.22390 1.000 24.68120 ? 99  LYS B CA  1 
ATOM   4851 C  C   . LYS B  1 99  ? 29.46490 1.54946   -77.31684 1.000 23.98481 ? 99  LYS B C   1 
ATOM   4852 O  O   . LYS B  1 99  ? 29.56591 1.23082   -76.12815 1.000 24.77059 ? 99  LYS B O   1 
ATOM   4853 C  CB  . LYS B  1 99  ? 27.08088 1.48942   -78.08304 1.000 25.46838 ? 99  LYS B CB  1 
ATOM   4854 C  CG  . LYS B  1 99  ? 25.98393 0.72856   -78.80999 1.000 28.77558 ? 99  LYS B CG  1 
ATOM   4855 C  CD  . LYS B  1 99  ? 24.60235 1.20304   -78.39688 1.000 23.52308 ? 99  LYS B CD  1 
ATOM   4856 C  CE  . LYS B  1 99  ? 23.52198 0.48618   -79.18988 1.000 33.85867 ? 99  LYS B CE  1 
ATOM   4857 N  NZ  . LYS B  1 99  ? 23.67720 -0.99308  -79.12265 1.000 42.31597 ? 99  LYS B NZ  1 
ATOM   4858 N  N   . THR B  1 100 ? 30.21526 2.49541   -77.88053 1.000 20.70854 ? 100 THR B N   1 
ATOM   4859 C  CA  . THR B  1 100 ? 31.28390 3.15065   -77.13993 1.000 18.99456 ? 100 THR B CA  1 
ATOM   4860 C  C   . THR B  1 100 ? 31.33504 4.63677   -77.45541 1.000 22.30338 ? 100 THR B C   1 
ATOM   4861 O  O   . THR B  1 100 ? 31.09037 5.05255   -78.59134 1.000 25.31638 ? 100 THR B O   1 
ATOM   4862 C  CB  . THR B  1 100 ? 32.65497 2.53495   -77.45213 1.000 19.21522 ? 100 THR B CB  1 
ATOM   4863 O  OG1 . THR B  1 100 ? 32.85025 2.49115   -78.87060 1.000 17.45364 ? 100 THR B OG1 1 
ATOM   4864 C  CG2 . THR B  1 100 ? 32.77005 1.13204   -76.87217 1.000 21.53935 ? 100 THR B CG2 1 
ATOM   4865 N  N   . VAL B  1 101 ? 31.66529 5.42466   -76.43602 1.000 17.75439 ? 101 VAL B N   1 
ATOM   4866 C  CA  . VAL B  1 101 ? 31.99169 6.83695   -76.59489 1.000 15.62521 ? 101 VAL B CA  1 
ATOM   4867 C  C   . VAL B  1 101 ? 32.80857 7.24786   -75.37789 1.000 15.53790 ? 101 VAL B C   1 
ATOM   4868 O  O   . VAL B  1 101 ? 32.48521 6.88146   -74.24443 1.000 17.99497 ? 101 VAL B O   1 
ATOM   4869 C  CB  . VAL B  1 101 ? 30.71978 7.70273   -76.77603 1.000 16.38163 ? 101 VAL B CB  1 
ATOM   4870 C  CG1 . VAL B  1 101 ? 29.82517 7.63666   -75.54733 1.000 13.72136 ? 101 VAL B CG1 1 
ATOM   4871 C  CG2 . VAL B  1 101 ? 31.09261 9.14067   -77.10214 1.000 15.17242 ? 101 VAL B CG2 1 
ATOM   4872 N  N   . VAL B  1 102 ? 33.88998 7.98374   -75.62059 1.000 12.97363 ? 102 VAL B N   1 
ATOM   4873 C  CA  . VAL B  1 102 ? 34.86502 8.30791   -74.58489 1.000 15.42858 ? 102 VAL B CA  1 
ATOM   4874 C  C   . VAL B  1 102 ? 34.57731 9.70090   -74.04637 1.000 12.69408 ? 102 VAL B C   1 
ATOM   4875 O  O   . VAL B  1 102 ? 34.41111 10.65412  -74.81781 1.000 11.80962 ? 102 VAL B O   1 
ATOM   4876 C  CB  . VAL B  1 102 ? 36.30300 8.20959   -75.12154 1.000 15.58441 ? 102 VAL B CB  1 
ATOM   4877 C  CG1 . VAL B  1 102 ? 37.30159 8.56020   -74.02774 1.000 11.25129 ? 102 VAL B CG1 1 
ATOM   4878 C  CG2 . VAL B  1 102 ? 36.56872 6.81185   -75.66019 1.000 14.34849 ? 102 VAL B CG2 1 
ATOM   4879 N  N   . HIS B  1 103 ? 34.52448 9.81868   -72.72189 1.000 12.13186 ? 103 HIS B N   1 
ATOM   4880 C  CA  . HIS B  1 103 ? 34.28457 11.08261  -72.04130 1.000 11.29083 ? 103 HIS B CA  1 
ATOM   4881 C  C   . HIS B  1 103 ? 35.46941 11.40800  -71.14457 1.000 12.63517 ? 103 HIS B C   1 
ATOM   4882 O  O   . HIS B  1 103 ? 35.88996 10.57321  -70.33668 1.000 15.23345 ? 103 HIS B O   1 
ATOM   4883 C  CB  . HIS B  1 103 ? 32.99972 11.02929  -71.21230 1.000 13.16555 ? 103 HIS B CB  1 
ATOM   4884 C  CG  . HIS B  1 103 ? 32.85343 12.17161  -70.25616 1.000 17.23065 ? 103 HIS B CG  1 
ATOM   4885 N  ND1 . HIS B  1 103 ? 32.77520 13.48382  -70.67058 1.000 16.81063 ? 103 HIS B ND1 1 
ATOM   4886 C  CD2 . HIS B  1 103 ? 32.77793 12.19890  -68.90449 1.000 15.50209 ? 103 HIS B CD2 1 
ATOM   4887 C  CE1 . HIS B  1 103 ? 32.65381 14.26973  -69.61575 1.000 16.09695 ? 103 HIS B CE1 1 
ATOM   4888 N  NE2 . HIS B  1 103 ? 32.65207 13.51495  -68.53188 1.000 13.42635 ? 103 HIS B NE2 1 
ATOM   4889 N  N   . LEU B  1 104 ? 36.00472 12.61747  -71.29048 1.000 13.68413 ? 104 LEU B N   1 
ATOM   4890 C  CA  . LEU B  1 104 ? 37.07613 13.10951  -70.42682 1.000 12.47239 ? 104 LEU B CA  1 
ATOM   4891 C  C   . LEU B  1 104 ? 36.42698 13.71400  -69.18880 1.000 13.58578 ? 104 LEU B C   1 
ATOM   4892 O  O   . LEU B  1 104 ? 35.93795 14.84640  -69.21743 1.000 14.36862 ? 104 LEU B O   1 
ATOM   4893 C  CB  . LEU B  1 104 ? 37.94301 14.12385  -71.16451 1.000 12.21299 ? 104 LEU B CB  1 
ATOM   4894 C  CG  . LEU B  1 104 ? 39.09218 14.73971  -70.36569 1.000 12.97591 ? 104 LEU B CG  1 
ATOM   4895 C  CD1 . LEU B  1 104 ? 40.02500 13.65865  -69.84837 1.000 9.78510  ? 104 LEU B CD1 1 
ATOM   4896 C  CD2 . LEU B  1 104 ? 39.85250 15.74964  -71.21109 1.000 11.76868 ? 104 LEU B CD2 1 
ATOM   4897 N  N   . HIS B  1 105 ? 36.41534 12.94968  -68.09904 1.000 13.43364 ? 105 HIS B N   1 
ATOM   4898 C  CA  . HIS B  1 105 ? 35.72602 13.36170  -66.88285 1.000 11.00744 ? 105 HIS B CA  1 
ATOM   4899 C  C   . HIS B  1 105 ? 36.39675 14.59372  -66.28896 1.000 15.20150 ? 105 HIS B C   1 
ATOM   4900 O  O   . HIS B  1 105 ? 37.58520 14.56072  -65.95085 1.000 12.45024 ? 105 HIS B O   1 
ATOM   4901 C  CB  . HIS B  1 105 ? 35.71781 12.21697  -65.87307 1.000 10.73047 ? 105 HIS B CB  1 
ATOM   4902 C  CG  . HIS B  1 105 ? 34.93119 12.50844  -64.63407 1.000 12.67923 ? 105 HIS B CG  1 
ATOM   4903 N  ND1 . HIS B  1 105 ? 33.68652 11.96647  -64.40007 1.000 12.72000 ? 105 HIS B ND1 1 
ATOM   4904 C  CD2 . HIS B  1 105 ? 35.20944 13.28761  -63.56232 1.000 11.73247 ? 105 HIS B CD2 1 
ATOM   4905 C  CE1 . HIS B  1 105 ? 33.23297 12.39541  -63.23633 1.000 13.18848 ? 105 HIS B CE1 1 
ATOM   4906 N  NE2 . HIS B  1 105 ? 34.13765 13.19930  -62.70766 1.000 13.95606 ? 105 HIS B NE2 1 
ATOM   4907 N  N   . GLY B  1 106 ? 35.63158 15.67700  -66.15584 1.000 16.33227 ? 106 GLY B N   1 
ATOM   4908 C  CA  . GLY B  1 106 ? 36.13038 16.90864  -65.58345 1.000 10.97349 ? 106 GLY B CA  1 
ATOM   4909 C  C   . GLY B  1 106 ? 36.84700 17.82745  -66.54701 1.000 10.82366 ? 106 GLY B C   1 
ATOM   4910 O  O   . GLY B  1 106 ? 37.33602 18.88177  -66.12191 1.000 14.51285 ? 106 GLY B O   1 
ATOM   4911 N  N   . GLY B  1 107 ? 36.92436 17.47257  -67.82783 1.000 13.10256 ? 107 GLY B N   1 
ATOM   4912 C  CA  . GLY B  1 107 ? 37.64375 18.29482  -68.78527 1.000 14.16114 ? 107 GLY B CA  1 
ATOM   4913 C  C   . GLY B  1 107 ? 36.78531 19.43751  -69.29209 1.000 15.08279 ? 107 GLY B C   1 
ATOM   4914 O  O   . GLY B  1 107 ? 35.61456 19.24707  -69.63775 1.000 15.89589 ? 107 GLY B O   1 
ATOM   4915 N  N   . ARG B  1 108 ? 37.36674 20.63685  -69.32795 1.000 17.35230 ? 108 ARG B N   1 
ATOM   4916 C  CA  . ARG B  1 108 ? 36.70609 21.80097  -69.91500 1.000 15.82635 ? 108 ARG B CA  1 
ATOM   4917 C  C   . ARG B  1 108 ? 36.68924 21.60191  -71.42798 1.000 15.83492 ? 108 ARG B C   1 
ATOM   4918 O  O   . ARG B  1 108 ? 37.54977 22.08267  -72.16864 1.000 20.31374 ? 108 ARG B O   1 
ATOM   4919 C  CB  . ARG B  1 108 ? 37.41757 23.08813  -69.51477 1.000 20.38904 ? 108 ARG B CB  1 
ATOM   4920 C  CG  . ARG B  1 108 ? 36.76885 24.34488  -70.06711 1.000 26.14969 ? 108 ARG B CG  1 
ATOM   4921 C  CD  . ARG B  1 108 ? 37.41788 25.60767  -69.52496 1.000 27.05292 ? 108 ARG B CD  1 
ATOM   4922 N  NE  . ARG B  1 108 ? 37.15232 25.79658  -68.10400 1.000 33.38066 ? 108 ARG B NE  1 
ATOM   4923 C  CZ  . ARG B  1 108 ? 37.21843 26.96563  -67.48119 1.000 40.55809 ? 108 ARG B CZ  1 
ATOM   4924 N  NH1 . ARG B  1 108 ? 37.51891 28.07894  -68.13094 1.000 34.24719 ? 108 ARG B NH1 1 
ATOM   4925 N  NH2 . ARG B  1 108 ? 36.96897 27.02064  -66.17565 1.000 30.58596 ? 108 ARG B NH2 1 
ATOM   4926 N  N   . THR B  1 109 ? 35.68300 20.86412  -71.89172 1.000 16.84048 ? 109 THR B N   1 
ATOM   4927 C  CA  . THR B  1 109 ? 35.63192 20.37765  -73.25758 1.000 16.40099 ? 109 THR B CA  1 
ATOM   4928 C  C   . THR B  1 109 ? 34.40169 20.91279  -73.97586 1.000 17.89085 ? 109 THR B C   1 
ATOM   4929 O  O   . THR B  1 109 ? 33.31342 20.93410  -73.39029 1.000 18.35293 ? 109 THR B O   1 
ATOM   4930 C  CB  . THR B  1 109 ? 35.59460 18.84290  -73.28546 1.000 15.49114 ? 109 THR B CB  1 
ATOM   4931 O  OG1 . THR B  1 109 ? 36.62004 18.32473  -72.43122 1.000 14.11300 ? 109 THR B OG1 1 
ATOM   4932 C  CG2 . THR B  1 109 ? 35.81473 18.32323  -74.70064 1.000 18.66810 ? 109 THR B CG2 1 
ATOM   4933 N  N   . PRO B  1 110 ? 34.53843 21.35899  -75.22485 1.000 22.47451 ? 110 PRO B N   1 
ATOM   4934 C  CA  . PRO B  1 110 ? 33.35484 21.69881  -76.00686 1.000 17.68589 ? 110 PRO B CA  1 
ATOM   4935 C  C   . PRO B  1 110 ? 32.46643 20.48447  -76.17156 1.000 16.30600 ? 110 PRO B C   1 
ATOM   4936 O  O   . PRO B  1 110 ? 32.93265 19.33370  -76.07868 1.000 17.52537 ? 110 PRO B O   1 
ATOM   4937 C  CB  . PRO B  1 110 ? 33.93830 22.16564  -77.34856 1.000 14.92731 ? 110 PRO B CB  1 
ATOM   4938 C  CG  . PRO B  1 110 ? 35.30014 22.63805  -77.01116 1.000 11.02437 ? 110 PRO B CG  1 
ATOM   4939 C  CD  . PRO B  1 110 ? 35.78467 21.73823  -75.90888 1.000 15.74830 ? 110 PRO B CD  1 
ATOM   4940 N  N   . PRO B  1 111 ? 31.16750 20.69134  -76.39261 1.000 16.33132 ? 111 PRO B N   1 
ATOM   4941 C  CA  . PRO B  1 111 ? 30.23436 19.55353  -76.39283 1.000 16.15605 ? 111 PRO B CA  1 
ATOM   4942 C  C   . PRO B  1 111 ? 30.50507 18.53393  -77.48696 1.000 16.40668 ? 111 PRO B C   1 
ATOM   4943 O  O   . PRO B  1 111 ? 30.23106 17.34424  -77.28835 1.000 18.88569 ? 111 PRO B O   1 
ATOM   4944 C  CB  . PRO B  1 111 ? 28.86817 20.22671  -76.57027 1.000 19.16124 ? 111 PRO B CB  1 
ATOM   4945 C  CG  . PRO B  1 111 ? 29.18171 21.53612  -77.22743 1.000 13.14248 ? 111 PRO B CG  1 
ATOM   4946 C  CD  . PRO B  1 111 ? 30.48759 21.97202  -76.66462 1.000 18.92483 ? 111 PRO B CD  1 
ATOM   4947 N  N   . ASP B  1 112 ? 31.04513 18.95476  -78.63332 1.000 17.92518 ? 112 ASP B N   1 
ATOM   4948 C  CA  . ASP B  1 112 ? 31.28873 18.01647  -79.72428 1.000 23.21854 ? 112 ASP B CA  1 
ATOM   4949 C  C   . ASP B  1 112 ? 32.38892 17.01093  -79.40300 1.000 20.74313 ? 112 ASP B C   1 
ATOM   4950 O  O   . ASP B  1 112 ? 32.50687 16.00091  -80.10482 1.000 22.78395 ? 112 ASP B O   1 
ATOM   4951 C  CB  . ASP B  1 112 ? 31.63771 18.77411  -81.00655 1.000 28.30110 ? 112 ASP B CB  1 
ATOM   4952 C  CG  . ASP B  1 112 ? 32.53017 19.97216  -80.75006 1.000 44.28311 ? 112 ASP B CG  1 
ATOM   4953 O  OD1 . ASP B  1 112 ? 32.12178 20.86098  -79.97068 1.000 33.26051 ? 112 ASP B OD1 1 
ATOM   4954 O  OD2 . ASP B  1 112 ? 33.64328 20.01992  -81.31685 1.000 45.04495 ? 112 ASP B OD2 1 
ATOM   4955 N  N   . SER B  1 113 ? 33.19216 17.26014  -78.36740 1.000 16.09645 ? 113 SER B N   1 
ATOM   4956 C  CA  . SER B  1 113 ? 34.25310 16.34596  -77.96087 1.000 18.35437 ? 113 SER B CA  1 
ATOM   4957 C  C   . SER B  1 113 ? 34.10149 15.88054  -76.51875 1.000 17.76952 ? 113 SER B C   1 
ATOM   4958 O  O   . SER B  1 113 ? 35.04285 15.30469  -75.96350 1.000 17.87310 ? 113 SER B O   1 
ATOM   4959 C  CB  . SER B  1 113 ? 35.62780 16.99735  -78.14835 1.000 17.86719 ? 113 SER B CB  1 
ATOM   4960 O  OG  . SER B  1 113 ? 35.89733 17.24858  -79.51597 1.000 23.74752 ? 113 SER B OG  1 
ATOM   4961 N  N   . ASP B  1 114 ? 32.94568 16.11147  -75.89925 1.000 18.06173 ? 114 ASP B N   1 
ATOM   4962 C  CA  . ASP B  1 114 ? 32.73387 15.77603  -74.49732 1.000 17.71576 ? 114 ASP B CA  1 
ATOM   4963 C  C   . ASP B  1 114 ? 32.31925 14.32427  -74.28335 1.000 20.18987 ? 114 ASP B C   1 
ATOM   4964 O  O   . ASP B  1 114 ? 32.38436 13.83771  -73.14808 1.000 15.91264 ? 114 ASP B O   1 
ATOM   4965 C  CB  . ASP B  1 114 ? 31.67756 16.71186  -73.89090 1.000 12.58594 ? 114 ASP B CB  1 
ATOM   4966 C  CG  . ASP B  1 114 ? 31.55873 16.56163  -72.39015 1.000 15.61880 ? 114 ASP B CG  1 
ATOM   4967 O  OD1 . ASP B  1 114 ? 32.58819 16.69459  -71.69659 1.000 16.31207 ? 114 ASP B OD1 1 
ATOM   4968 O  OD2 . ASP B  1 114 ? 30.43699 16.31236  -71.90359 1.000 22.68970 ? 114 ASP B OD2 1 
ATOM   4969 N  N   . GLY B  1 115 ? 31.89967 13.62271  -75.33228 1.000 16.95672 ? 115 GLY B N   1 
ATOM   4970 C  CA  . GLY B  1 115 ? 31.50529 12.23457  -75.19106 1.000 14.30240 ? 115 GLY B CA  1 
ATOM   4971 C  C   . GLY B  1 115 ? 30.05542 12.06055  -74.78801 1.000 17.82715 ? 115 GLY B C   1 
ATOM   4972 O  O   . GLY B  1 115 ? 29.75424 11.39444  -73.79184 1.000 18.30573 ? 115 GLY B O   1 
ATOM   4973 N  N   . TYR B  1 116 ? 29.15291 12.66448  -75.55470 1.000 15.16668 ? 116 TYR B N   1 
ATOM   4974 C  CA  . TYR B  1 116 ? 27.73201 12.56341  -75.26134 1.000 14.76083 ? 116 TYR B CA  1 
ATOM   4975 C  C   . TYR B  1 116 ? 27.30071 11.09820  -75.29211 1.000 17.65866 ? 116 TYR B C   1 
ATOM   4976 O  O   . TYR B  1 116 ? 27.75563 10.33668  -76.15439 1.000 18.44142 ? 116 TYR B O   1 
ATOM   4977 C  CB  . TYR B  1 116 ? 26.92644 13.38112  -76.27376 1.000 16.77263 ? 116 TYR B CB  1 
ATOM   4978 C  CG  . TYR B  1 116 ? 25.49140 13.64529  -75.87359 1.000 15.95405 ? 116 TYR B CG  1 
ATOM   4979 C  CD1 . TYR B  1 116 ? 25.19228 14.45134  -74.78333 1.000 17.99351 ? 116 TYR B CD1 1 
ATOM   4980 C  CD2 . TYR B  1 116 ? 24.43625 13.10615  -76.59790 1.000 13.43283 ? 116 TYR B CD2 1 
ATOM   4981 C  CE1 . TYR B  1 116 ? 23.88463 14.69736  -74.41426 1.000 16.32516 ? 116 TYR B CE1 1 
ATOM   4982 C  CE2 . TYR B  1 116 ? 23.12424 13.35227  -76.23932 1.000 16.41857 ? 116 TYR B CE2 1 
ATOM   4983 C  CZ  . TYR B  1 116 ? 22.85509 14.15006  -75.14624 1.000 16.67587 ? 116 TYR B CZ  1 
ATOM   4984 O  OH  . TYR B  1 116 ? 21.55311 14.40031  -74.78142 1.000 17.43158 ? 116 TYR B OH  1 
ATOM   4985 N  N   . PRO B  1 117 ? 26.44391 10.66557  -74.36178 1.000 14.42371 ? 117 PRO B N   1 
ATOM   4986 C  CA  . PRO B  1 117 ? 26.08060 9.23940   -74.30888 1.000 15.89782 ? 117 PRO B CA  1 
ATOM   4987 C  C   . PRO B  1 117 ? 25.46321 8.71543   -75.59186 1.000 19.02567 ? 117 PRO B C   1 
ATOM   4988 O  O   . PRO B  1 117 ? 25.66013 7.54087   -75.92665 1.000 16.20546 ? 117 PRO B O   1 
ATOM   4989 C  CB  . PRO B  1 117 ? 25.08620 9.17723   -73.14073 1.000 17.81778 ? 117 PRO B CB  1 
ATOM   4990 C  CG  . PRO B  1 117 ? 25.41949 10.35804  -72.29690 1.000 16.33179 ? 117 PRO B CG  1 
ATOM   4991 C  CD  . PRO B  1 117 ? 25.84472 11.42942  -73.25512 1.000 15.55651 ? 117 PRO B CD  1 
ATOM   4992 N  N   . GLU B  1 118 ? 24.72441 9.54558   -76.32339 1.000 19.07754 ? 118 GLU B N   1 
ATOM   4993 C  CA  . GLU B  1 118 ? 24.09449 9.12910   -77.56666 1.000 17.93817 ? 118 GLU B CA  1 
ATOM   4994 C  C   . GLU B  1 118 ? 24.93349 9.46936   -78.79095 1.000 21.41748 ? 118 GLU B C   1 
ATOM   4995 O  O   . GLU B  1 118 ? 24.45787 9.31519   -79.92012 1.000 23.23232 ? 118 GLU B O   1 
ATOM   4996 C  CB  . GLU B  1 118 ? 22.69869 9.74378   -77.67729 1.000 17.50478 ? 118 GLU B CB  1 
ATOM   4997 C  CG  . GLU B  1 118 ? 21.71024 9.11530   -76.71031 1.000 19.66782 ? 118 GLU B CG  1 
ATOM   4998 C  CD  . GLU B  1 118 ? 20.34574 9.76361   -76.74668 1.000 24.31153 ? 118 GLU B CD  1 
ATOM   4999 O  OE1 . GLU B  1 118 ? 20.23566 10.89995  -77.25166 1.000 31.43008 ? 118 GLU B OE1 1 
ATOM   5000 O  OE2 . GLU B  1 118 ? 19.38094 9.13403   -76.26498 1.000 27.84358 ? 118 GLU B OE2 1 
ATOM   5001 N  N   . ALA B  1 119 ? 26.16972 9.93081   -78.59261 1.000 24.53997 ? 119 ALA B N   1 
ATOM   5002 C  CA  . ALA B  1 119 ? 27.14485 10.05220  -79.66891 1.000 22.72493 ? 119 ALA B CA  1 
ATOM   5003 C  C   . ALA B  1 119 ? 28.02933 8.81714   -79.78362 1.000 24.02279 ? 119 ALA B C   1 
ATOM   5004 O  O   . ALA B  1 119 ? 29.17898 8.91579   -80.23671 1.000 18.98918 ? 119 ALA B O   1 
ATOM   5005 C  CB  . ALA B  1 119 ? 27.99777 11.30612  -79.47123 1.000 18.80107 ? 119 ALA B CB  1 
ATOM   5006 N  N   . TRP B  1 120 ? 27.51935 7.65494   -79.38059 1.000 21.26825 ? 120 TRP B N   1 
ATOM   5007 C  CA  . TRP B  1 120 ? 28.30577 6.43385   -79.38359 1.000 20.24659 ? 120 TRP B CA  1 
ATOM   5008 C  C   . TRP B  1 120 ? 28.52301 5.93032   -80.80872 1.000 23.61594 ? 120 TRP B C   1 
ATOM   5009 O  O   . TRP B  1 120 ? 27.98391 6.46130   -81.78431 1.000 24.17404 ? 120 TRP B O   1 
ATOM   5010 C  CB  . TRP B  1 120 ? 27.62605 5.35229   -78.54319 1.000 23.24827 ? 120 TRP B CB  1 
ATOM   5011 C  CG  . TRP B  1 120 ? 26.19883 5.08211   -78.92969 1.000 21.75223 ? 120 TRP B CG  1 
ATOM   5012 C  CD1 . TRP B  1 120 ? 25.08149 5.58063   -78.32748 1.000 21.17424 ? 120 TRP B CD1 1 
ATOM   5013 C  CD2 . TRP B  1 120 ? 25.73684 4.24795   -80.00205 1.000 26.93335 ? 120 TRP B CD2 1 
ATOM   5014 N  NE1 . TRP B  1 120 ? 23.95370 5.11118   -78.95568 1.000 20.91578 ? 120 TRP B NE1 1 
ATOM   5015 C  CE2 . TRP B  1 120 ? 24.32843 4.29133   -79.98703 1.000 22.27151 ? 120 TRP B CE2 1 
ATOM   5016 C  CE3 . TRP B  1 120 ? 26.37672 3.46932   -80.97245 1.000 27.38374 ? 120 TRP B CE3 1 
ATOM   5017 C  CZ2 . TRP B  1 120 ? 23.54984 3.58789   -80.90364 1.000 18.79337 ? 120 TRP B CZ2 1 
ATOM   5018 C  CZ3 . TRP B  1 120 ? 25.60161 2.77109   -81.88135 1.000 22.92123 ? 120 TRP B CZ3 1 
ATOM   5019 C  CH2 . TRP B  1 120 ? 24.20343 2.83535   -81.84017 1.000 22.61837 ? 120 TRP B CH2 1 
ATOM   5020 N  N   . TYR B  1 121 ? 29.32271 4.87301   -80.91263 1.000 24.38446 ? 121 TYR B N   1 
ATOM   5021 C  CA  . TYR B  1 121 ? 29.65009 4.26548   -82.19248 1.000 21.68423 ? 121 TYR B CA  1 
ATOM   5022 C  C   . TYR B  1 121 ? 30.12666 2.84478   -81.94100 1.000 19.53828 ? 121 TYR B C   1 
ATOM   5023 O  O   . TYR B  1 121 ? 30.68538 2.54358   -80.88301 1.000 18.66035 ? 121 TYR B O   1 
ATOM   5024 C  CB  . TYR B  1 121 ? 30.72119 5.06867   -82.94012 1.000 18.43320 ? 121 TYR B CB  1 
ATOM   5025 C  CG  . TYR B  1 121 ? 31.90902 5.43987   -82.08150 1.000 17.16002 ? 121 TYR B CG  1 
ATOM   5026 C  CD1 . TYR B  1 121 ? 33.00778 4.59696   -81.97749 1.000 18.98793 ? 121 TYR B CD1 1 
ATOM   5027 C  CD2 . TYR B  1 121 ? 31.92925 6.63311   -81.37144 1.000 17.79084 ? 121 TYR B CD2 1 
ATOM   5028 C  CE1 . TYR B  1 121 ? 34.09340 4.93383   -81.19198 1.000 17.94240 ? 121 TYR B CE1 1 
ATOM   5029 C  CE2 . TYR B  1 121 ? 33.00756 6.97755   -80.58428 1.000 14.71778 ? 121 TYR B CE2 1 
ATOM   5030 C  CZ  . TYR B  1 121 ? 34.08625 6.12596   -80.49853 1.000 19.82530 ? 121 TYR B CZ  1 
ATOM   5031 O  OH  . TYR B  1 121 ? 35.16119 6.47000   -79.71470 1.000 23.38901 ? 121 TYR B OH  1 
ATOM   5032 N  N   . THR B  1 122 ? 29.89554 1.97759   -82.91964 1.000 20.09089 ? 122 THR B N   1 
ATOM   5033 C  CA  . THR B  1 122 ? 30.35447 0.59887   -82.84140 1.000 21.57414 ? 122 THR B CA  1 
ATOM   5034 C  C   . THR B  1 122 ? 31.73599 0.49969   -83.49389 1.000 19.45482 ? 122 THR B C   1 
ATOM   5035 O  O   . THR B  1 122 ? 32.40871 1.51237   -83.70444 1.000 22.32213 ? 122 THR B O   1 
ATOM   5036 C  CB  . THR B  1 122 ? 29.31965 -0.33413  -83.47818 1.000 22.21242 ? 122 THR B CB  1 
ATOM   5037 O  OG1 . THR B  1 122 ? 28.99950 0.12871   -84.79636 1.000 27.72455 ? 122 THR B OG1 1 
ATOM   5038 C  CG2 . THR B  1 122 ? 28.05368 -0.37844  -82.63659 1.000 15.85169 ? 122 THR B CG2 1 
ATOM   5039 N  N   . LYS B  1 123 ? 32.17263 -0.71409  -83.82112 1.000 17.57337 ? 123 LYS B N   1 
ATOM   5040 C  CA  . LYS B  1 123 ? 33.50979 -0.90930  -84.36647 1.000 22.74025 ? 123 LYS B CA  1 
ATOM   5041 C  C   . LYS B  1 123 ? 33.65684 -0.21776  -85.71662 1.000 26.74032 ? 123 LYS B C   1 
ATOM   5042 O  O   . LYS B  1 123 ? 32.78456 -0.32669  -86.58388 1.000 28.98148 ? 123 LYS B O   1 
ATOM   5043 C  CB  . LYS B  1 123 ? 33.80758 -2.40146  -84.50304 1.000 26.79044 ? 123 LYS B CB  1 
ATOM   5044 C  CG  . LYS B  1 123 ? 35.09971 -2.70613  -85.23653 1.000 25.10162 ? 123 LYS B CG  1 
ATOM   5045 C  CD  . LYS B  1 123 ? 35.30690 -4.20099  -85.39003 1.000 29.98461 ? 123 LYS B CD  1 
ATOM   5046 C  CE  . LYS B  1 123 ? 36.51293 -4.49649  -86.26273 1.000 28.19896 ? 123 LYS B CE  1 
ATOM   5047 N  NZ  . LYS B  1 123 ? 36.76179 -5.95765  -86.38951 1.000 43.74155 ? 123 LYS B NZ  1 
ATOM   5048 N  N   . ASP B  1 124 ? 34.76985 0.50137   -85.88387 1.000 25.41520 ? 124 ASP B N   1 
ATOM   5049 C  CA  . ASP B  1 124 ? 35.09586 1.20465   -87.12661 1.000 25.81909 ? 124 ASP B CA  1 
ATOM   5050 C  C   . ASP B  1 124 ? 34.00176 2.18793   -87.53019 1.000 23.69567 ? 124 ASP B C   1 
ATOM   5051 O  O   . ASP B  1 124 ? 33.82305 2.47744   -88.71579 1.000 25.04389 ? 124 ASP B O   1 
ATOM   5052 C  CB  . ASP B  1 124 ? 35.37668 0.22214   -88.26775 1.000 20.39382 ? 124 ASP B CB  1 
ATOM   5053 C  CG  . ASP B  1 124 ? 36.58433 -0.65320  -87.99837 1.000 31.49585 ? 124 ASP B CG  1 
ATOM   5054 O  OD1 . ASP B  1 124 ? 37.44346 -0.24897  -87.18652 1.000 36.87172 ? 124 ASP B OD1 1 
ATOM   5055 O  OD2 . ASP B  1 124 ? 36.67681 -1.74395  -88.60040 1.000 37.47340 ? 124 ASP B OD2 1 
ATOM   5056 N  N   . PHE B  1 125 ? 33.26837 2.70554   -86.54293 1.000 23.32369 ? 125 PHE B N   1 
ATOM   5057 C  CA  . PHE B  1 125 ? 32.18020 3.65731   -86.76720 1.000 21.86905 ? 125 PHE B CA  1 
ATOM   5058 C  C   . PHE B  1 125 ? 31.11850 3.09876   -87.71169 1.000 21.38258 ? 125 PHE B C   1 
ATOM   5059 O  O   . PHE B  1 125 ? 30.49091 3.84917   -88.46305 1.000 21.04749 ? 125 PHE B O   1 
ATOM   5060 C  CB  . PHE B  1 125 ? 32.70847 4.99693   -87.29201 1.000 21.21633 ? 125 PHE B CB  1 
ATOM   5061 C  CG  . PHE B  1 125 ? 33.77380 5.61015   -86.42776 1.000 24.38045 ? 125 PHE B CG  1 
ATOM   5062 C  CD1 . PHE B  1 125 ? 33.43599 6.33645   -85.29703 1.000 23.54836 ? 125 PHE B CD1 1 
ATOM   5063 C  CD2 . PHE B  1 125 ? 35.11334 5.46502   -86.74884 1.000 23.33601 ? 125 PHE B CD2 1 
ATOM   5064 C  CE1 . PHE B  1 125 ? 34.41530 6.90268   -84.49892 1.000 22.36260 ? 125 PHE B CE1 1 
ATOM   5065 C  CE2 . PHE B  1 125 ? 36.09806 6.03026   -85.95612 1.000 23.75331 ? 125 PHE B CE2 1 
ATOM   5066 C  CZ  . PHE B  1 125 ? 35.74781 6.74884   -84.82934 1.000 23.28185 ? 125 PHE B CZ  1 
ATOM   5067 N  N   . GLN B  1 126 ? 30.91481 1.77898   -87.68629 1.000 19.85970 ? 126 GLN B N   1 
ATOM   5068 C  CA  . GLN B  1 126 ? 29.87493 1.14672   -88.49147 1.000 23.02554 ? 126 GLN B CA  1 
ATOM   5069 C  C   . GLN B  1 126 ? 28.51266 1.74561   -88.17288 1.000 27.82203 ? 126 GLN B C   1 
ATOM   5070 O  O   . GLN B  1 126 ? 27.89719 2.39967   -89.02067 1.000 34.37244 ? 126 GLN B O   1 
ATOM   5071 C  CB  . GLN B  1 126 ? 29.84004 -0.36460  -88.25575 1.000 31.09474 ? 126 GLN B CB  1 
ATOM   5072 C  CG  . GLN B  1 126 ? 30.72248 -1.17961  -89.18219 1.000 34.00099 ? 126 GLN B CG  1 
ATOM   5073 C  CD  . GLN B  1 126 ? 30.32855 -2.64542  -89.20309 1.000 53.65910 ? 126 GLN B CD  1 
ATOM   5074 O  OE1 . GLN B  1 126 ? 29.14331 -2.98120  -89.18200 1.000 52.07153 ? 126 GLN B OE1 1 
ATOM   5075 N  NE2 . GLN B  1 126 ? 31.32198 -3.52644  -89.23722 1.000 56.87950 ? 126 GLN B NE2 1 
ATOM   5076 N  N   . VAL B  1 127 ? 28.03619 1.52145   -86.95325 1.000 26.42303 ? 127 VAL B N   1 
ATOM   5077 C  CA  . VAL B  1 127 ? 26.78725 2.09618   -86.47169 1.000 32.19049 ? 127 VAL B CA  1 
ATOM   5078 C  C   . VAL B  1 127 ? 27.12760 3.27320   -85.57027 1.000 27.50950 ? 127 VAL B C   1 
ATOM   5079 O  O   . VAL B  1 127 ? 28.01292 3.17018   -84.71214 1.000 29.52175 ? 127 VAL B O   1 
ATOM   5080 C  CB  . VAL B  1 127 ? 25.94448 1.04946   -85.72351 1.000 27.48306 ? 127 VAL B CB  1 
ATOM   5081 C  CG1 . VAL B  1 127 ? 24.56465 1.60454   -85.40895 1.000 22.45124 ? 127 VAL B CG1 1 
ATOM   5082 C  CG2 . VAL B  1 127 ? 25.84556 -0.23201  -86.53927 1.000 20.70678 ? 127 VAL B CG2 1 
ATOM   5083 N  N   . LYS B  1 128 ? 26.43573 4.39229   -85.76663 1.000 23.85971 ? 128 LYS B N   1 
ATOM   5084 C  CA  . LYS B  1 128 ? 26.68077 5.61199   -85.01193 1.000 21.19620 ? 128 LYS B CA  1 
ATOM   5085 C  C   . LYS B  1 128 ? 25.41266 6.02893   -84.28138 1.000 26.46033 ? 128 LYS B C   1 
ATOM   5086 O  O   . LYS B  1 128 ? 24.30605 5.89864   -84.81468 1.000 26.91636 ? 128 LYS B O   1 
ATOM   5087 C  CB  . LYS B  1 128 ? 27.14625 6.74837   -85.92977 1.000 24.54051 ? 128 LYS B CB  1 
ATOM   5088 C  CG  . LYS B  1 128 ? 28.10284 6.31585   -87.02980 1.000 28.04778 ? 128 LYS B CG  1 
ATOM   5089 C  CD  . LYS B  1 128 ? 28.51138 7.49844   -87.89392 1.000 29.71419 ? 128 LYS B CD  1 
ATOM   5090 C  CE  . LYS B  1 128 ? 29.04001 7.04902   -89.24559 1.000 36.41504 ? 128 LYS B CE  1 
ATOM   5091 N  NZ  . LYS B  1 128 ? 27.97343 6.40204   -90.06121 1.000 45.32129 ? 128 LYS B NZ  1 
ATOM   5092 N  N   . GLY B  1 129 ? 25.57930 6.53203   -83.06043 1.000 25.75160 ? 129 GLY B N   1 
ATOM   5093 C  CA  . GLY B  1 129 ? 24.47006 7.03351   -82.28617 1.000 18.66580 ? 129 GLY B CA  1 
ATOM   5094 C  C   . GLY B  1 129 ? 23.85843 8.26816   -82.91607 1.000 19.94604 ? 129 GLY B C   1 
ATOM   5095 O  O   . GLY B  1 129 ? 24.46953 8.92758   -83.76325 1.000 20.37070 ? 129 GLY B O   1 
ATOM   5096 N  N   . PRO B  1 130 ? 22.63345 8.61070   -82.50587 1.000 16.26669 ? 130 PRO B N   1 
ATOM   5097 C  CA  . PRO B  1 130 ? 21.93109 9.74033   -83.13920 1.000 14.57361 ? 130 PRO B CA  1 
ATOM   5098 C  C   . PRO B  1 130 ? 22.60268 11.08897  -82.93104 1.000 19.09096 ? 130 PRO B C   1 
ATOM   5099 O  O   . PRO B  1 130 ? 22.24668 12.04612  -83.63033 1.000 24.66851 ? 130 PRO B O   1 
ATOM   5100 C  CB  . PRO B  1 130 ? 20.54295 9.70510   -82.48415 1.000 14.54075 ? 130 PRO B CB  1 
ATOM   5101 C  CG  . PRO B  1 130 ? 20.74702 8.97518   -81.19444 1.000 19.21452 ? 130 PRO B CG  1 
ATOM   5102 C  CD  . PRO B  1 130 ? 21.81756 7.96016   -81.46663 1.000 20.30517 ? 130 PRO B CD  1 
ATOM   5103 N  N   . PHE B  1 131 ? 23.55743 11.20065  -82.00778 1.000 17.88465 ? 131 PHE B N   1 
ATOM   5104 C  CA  . PHE B  1 131 ? 24.25446 12.45524  -81.75362 1.000 17.28504 ? 131 PHE B CA  1 
ATOM   5105 C  C   . PHE B  1 131 ? 25.71148 12.40988  -82.19992 1.000 18.66665 ? 131 PHE B C   1 
ATOM   5106 O  O   . PHE B  1 131 ? 26.50999 13.25491  -81.78292 1.000 23.36405 ? 131 PHE B O   1 
ATOM   5107 C  CB  . PHE B  1 131 ? 24.16442 12.82088  -80.27148 1.000 20.54756 ? 131 PHE B CB  1 
ATOM   5108 C  CG  . PHE B  1 131 ? 22.83340 13.38994  -79.86678 1.000 27.18141 ? 131 PHE B CG  1 
ATOM   5109 C  CD1 . PHE B  1 131 ? 21.70610 12.58540  -79.81088 1.000 21.93847 ? 131 PHE B CD1 1 
ATOM   5110 C  CD2 . PHE B  1 131 ? 22.71177 14.72912  -79.53388 1.000 27.67376 ? 131 PHE B CD2 1 
ATOM   5111 C  CE1 . PHE B  1 131 ? 20.48264 13.10858  -79.43619 1.000 24.90544 ? 131 PHE B CE1 1 
ATOM   5112 C  CE2 . PHE B  1 131 ? 21.49185 15.25658  -79.15735 1.000 28.48400 ? 131 PHE B CE2 1 
ATOM   5113 C  CZ  . PHE B  1 131 ? 20.37567 14.44485  -79.10934 1.000 25.13765 ? 131 PHE B CZ  1 
ATOM   5114 N  N   . PHE B  1 132 ? 26.07418 11.44105  -83.03669 1.000 16.98839 ? 132 PHE B N   1 
ATOM   5115 C  CA  . PHE B  1 132 ? 27.44794 11.33808  -83.50647 1.000 17.39449 ? 132 PHE B CA  1 
ATOM   5116 C  C   . PHE B  1 132 ? 27.77040 12.47399  -84.46836 1.000 20.31600 ? 132 PHE B C   1 
ATOM   5117 O  O   . PHE B  1 132 ? 26.92768 12.89179  -85.26692 1.000 21.24874 ? 132 PHE B O   1 
ATOM   5118 C  CB  . PHE B  1 132 ? 27.67774 9.99280   -84.19071 1.000 17.01316 ? 132 PHE B CB  1 
ATOM   5119 C  CG  . PHE B  1 132 ? 29.09626 9.77362   -84.62550 1.000 23.45493 ? 132 PHE B CG  1 
ATOM   5120 C  CD1 . PHE B  1 132 ? 30.01984 9.21554   -83.75803 1.000 18.43109 ? 132 PHE B CD1 1 
ATOM   5121 C  CD2 . PHE B  1 132 ? 29.50996 10.13156  -85.89890 1.000 25.02161 ? 132 PHE B CD2 1 
ATOM   5122 C  CE1 . PHE B  1 132 ? 31.32802 9.01547   -84.15252 1.000 20.59157 ? 132 PHE B CE1 1 
ATOM   5123 C  CE2 . PHE B  1 132 ? 30.81713 9.93451   -86.29894 1.000 26.05707 ? 132 PHE B CE2 1 
ATOM   5124 C  CZ  . PHE B  1 132 ? 31.72761 9.37535   -85.42460 1.000 23.66031 ? 132 PHE B CZ  1 
ATOM   5125 N  N   . GLU B  1 133 ? 29.00537 12.97035  -84.39523 1.000 21.17724 ? 133 GLU B N   1 
ATOM   5126 C  CA  . GLU B  1 133 ? 29.42116 14.06697  -85.26107 1.000 27.55932 ? 133 GLU B CA  1 
ATOM   5127 C  C   . GLU B  1 133 ? 30.81155 13.85339  -85.84599 1.000 25.23540 ? 133 GLU B C   1 
ATOM   5128 O  O   . GLU B  1 133 ? 31.02427 14.07448  -87.04237 1.000 27.43547 ? 133 GLU B O   1 
ATOM   5129 C  CB  . GLU B  1 133 ? 29.38666 15.39397  -84.49992 1.000 28.09467 ? 133 GLU B CB  1 
ATOM   5130 C  CG  . GLU B  1 133 ? 27.99554 15.96439  -84.29640 1.000 35.32857 ? 133 GLU B CG  1 
ATOM   5131 C  CD  . GLU B  1 133 ? 28.02634 17.36230  -83.71130 1.000 49.21861 ? 133 GLU B CD  1 
ATOM   5132 O  OE1 . GLU B  1 133 ? 29.10265 17.99734  -83.74350 1.000 49.98570 ? 133 GLU B OE1 1 
ATOM   5133 O  OE2 . GLU B  1 133 ? 26.97638 17.82503  -83.21741 1.000 57.39011 ? 133 GLU B OE2 1 
ATOM   5134 N  N   . ARG B  1 134 ? 31.76509 13.43193  -85.01849 1.000 32.02732 ? 134 ARG B N   1 
ATOM   5135 C  CA  . ARG B  1 134 ? 33.16581 13.43488  -85.41250 1.000 28.52200 ? 134 ARG B CA  1 
ATOM   5136 C  C   . ARG B  1 134 ? 33.87687 12.21080  -84.85602 1.000 24.79289 ? 134 ARG B C   1 
ATOM   5137 O  O   . ARG B  1 134 ? 33.46462 11.62689  -83.85165 1.000 26.27643 ? 134 ARG B O   1 
ATOM   5138 C  CB  . ARG B  1 134 ? 33.86572 14.71028  -84.93202 1.000 26.50704 ? 134 ARG B CB  1 
ATOM   5139 C  CG  . ARG B  1 134 ? 33.60075 15.02771  -83.47121 1.000 23.97791 ? 134 ARG B CG  1 
ATOM   5140 C  CD  . ARG B  1 134 ? 33.68073 16.51961  -83.22445 1.000 27.26464 ? 134 ARG B CD  1 
ATOM   5141 N  NE  . ARG B  1 134 ? 34.99298 16.94008  -82.74996 1.000 34.40596 ? 134 ARG B NE  1 
ATOM   5142 C  CZ  . ARG B  1 134 ? 35.58023 18.07730  -83.09584 1.000 30.85798 ? 134 ARG B CZ  1 
ATOM   5143 N  NH1 . ARG B  1 134 ? 35.02785 18.90102  -83.97102 1.000 28.80447 ? 134 ARG B NH1 1 
ATOM   5144 N  NH2 . ARG B  1 134 ? 36.75409 18.39254  -82.55630 1.000 29.56622 ? 134 ARG B NH2 1 
ATOM   5145 N  N   . GLU B  1 135 ? 34.96721 11.83647  -85.52660 1.000 29.13837 ? 135 GLU B N   1 
ATOM   5146 C  CA  . GLU B  1 135 ? 35.81124 10.73296  -85.08948 1.000 23.60915 ? 135 GLU B CA  1 
ATOM   5147 C  C   . GLU B  1 135 ? 36.98770 11.18547  -84.23798 1.000 17.67778 ? 135 GLU B C   1 
ATOM   5148 O  O   . GLU B  1 135 ? 37.50858 10.38855  -83.44903 1.000 18.35171 ? 135 GLU B O   1 
ATOM   5149 C  CB  . GLU B  1 135 ? 36.34512 9.96224   -86.30147 1.000 23.02637 ? 135 GLU B CB  1 
ATOM   5150 C  CG  . GLU B  1 135 ? 35.27260 9.42310   -87.22515 1.000 24.53074 ? 135 GLU B CG  1 
ATOM   5151 C  CD  . GLU B  1 135 ? 35.85421 8.69289   -88.41617 1.000 25.57020 ? 135 GLU B CD  1 
ATOM   5152 O  OE1 . GLU B  1 135 ? 37.08155 8.78188   -88.62615 1.000 30.40885 ? 135 GLU B OE1 1 
ATOM   5153 O  OE2 . GLU B  1 135 ? 35.08569 8.02768   -89.14119 1.000 40.66326 ? 135 GLU B OE2 1 
ATOM   5154 N  N   . VAL B  1 136 ? 37.42191 12.43394  -84.38150 1.000 20.15492 ? 136 VAL B N   1 
ATOM   5155 C  CA  . VAL B  1 136 ? 38.57165 12.96204  -83.65787 1.000 20.36615 ? 136 VAL B CA  1 
ATOM   5156 C  C   . VAL B  1 136 ? 38.07227 14.01596  -82.68018 1.000 19.16176 ? 136 VAL B C   1 
ATOM   5157 O  O   . VAL B  1 136 ? 37.48318 15.02432  -83.08926 1.000 19.17317 ? 136 VAL B O   1 
ATOM   5158 C  CB  . VAL B  1 136 ? 39.62267 13.54919  -84.61293 1.000 17.07203 ? 136 VAL B CB  1 
ATOM   5159 C  CG1 . VAL B  1 136 ? 40.84359 14.02485  -83.83356 1.000 19.10157 ? 136 VAL B CG1 1 
ATOM   5160 C  CG2 . VAL B  1 136 ? 40.01983 12.52662  -85.66428 1.000 13.38344 ? 136 VAL B CG2 1 
ATOM   5161 N  N   . TYR B  1 137 ? 38.30218 13.78210  -81.39198 1.000 20.17915 ? 137 TYR B N   1 
ATOM   5162 C  CA  . TYR B  1 137 ? 37.97433 14.75416  -80.36075 1.000 23.08548 ? 137 TYR B CA  1 
ATOM   5163 C  C   . TYR B  1 137 ? 39.14036 15.71328  -80.16478 1.000 20.69059 ? 137 TYR B C   1 
ATOM   5164 O  O   . TYR B  1 137 ? 40.30281 15.35265  -80.36370 1.000 22.42997 ? 137 TYR B O   1 
ATOM   5165 C  CB  . TYR B  1 137 ? 37.64726 14.06412  -79.03389 1.000 19.05858 ? 137 TYR B CB  1 
ATOM   5166 C  CG  . TYR B  1 137 ? 36.29408 13.38756  -78.98146 1.000 17.46142 ? 137 TYR B CG  1 
ATOM   5167 C  CD1 . TYR B  1 137 ? 35.47876 13.31918  -80.10415 1.000 18.48667 ? 137 TYR B CD1 1 
ATOM   5168 C  CD2 . TYR B  1 137 ? 35.82705 12.82882  -77.79890 1.000 15.07702 ? 137 TYR B CD2 1 
ATOM   5169 C  CE1 . TYR B  1 137 ? 34.24125 12.70264  -80.05193 1.000 22.49896 ? 137 TYR B CE1 1 
ATOM   5170 C  CE2 . TYR B  1 137 ? 34.59301 12.21407  -77.73638 1.000 16.88363 ? 137 TYR B CE2 1 
ATOM   5171 C  CZ  . TYR B  1 137 ? 33.80331 12.15311  -78.86412 1.000 22.60894 ? 137 TYR B CZ  1 
ATOM   5172 O  OH  . TYR B  1 137 ? 32.57198 11.53965  -78.80190 1.000 24.00632 ? 137 TYR B OH  1 
ATOM   5173 N  N   . GLU B  1 138 ? 38.81930 16.94422  -79.77121 1.000 16.82024 ? 138 GLU B N   1 
ATOM   5174 C  CA  . GLU B  1 138 ? 39.82420 17.96422  -79.50078 1.000 18.58213 ? 138 GLU B CA  1 
ATOM   5175 C  C   . GLU B  1 138 ? 39.59310 18.54596  -78.11536 1.000 21.42387 ? 138 GLU B C   1 
ATOM   5176 O  O   . GLU B  1 138 ? 38.47334 18.95073  -77.78637 1.000 17.10167 ? 138 GLU B O   1 
ATOM   5177 C  CB  . GLU B  1 138 ? 39.79416 19.07615  -80.55445 1.000 19.32949 ? 138 GLU B CB  1 
ATOM   5178 C  CG  . GLU B  1 138 ? 40.52114 18.72754  -81.84301 1.000 37.55045 ? 138 GLU B CG  1 
ATOM   5179 C  CD  . GLU B  1 138 ? 40.58878 19.89481  -82.80824 1.000 54.45273 ? 138 GLU B CD  1 
ATOM   5180 O  OE1 . GLU B  1 138 ? 41.26853 19.76912  -83.84927 1.000 59.61275 ? 138 GLU B OE1 1 
ATOM   5181 O  OE2 . GLU B  1 138 ? 39.96001 20.93737  -82.52662 1.000 69.86226 ? 138 GLU B OE2 1 
ATOM   5182 N  N   . TYR B  1 139 ? 40.64963 18.58691  -77.31276 1.000 15.31731 ? 139 TYR B N   1 
ATOM   5183 C  CA  . TYR B  1 139 ? 40.58258 19.12084  -75.95381 1.000 16.34936 ? 139 TYR B CA  1 
ATOM   5184 C  C   . TYR B  1 139 ? 41.45211 20.36431  -75.85411 1.000 18.31213 ? 139 TYR B C   1 
ATOM   5185 O  O   . TYR B  1 139 ? 42.69266 20.25372  -75.89170 1.000 17.97170 ? 139 TYR B O   1 
ATOM   5186 C  CB  . TYR B  1 139 ? 41.02718 18.06899  -74.93819 1.000 15.26256 ? 139 TYR B CB  1 
ATOM   5187 C  CG  . TYR B  1 139 ? 40.25921 16.77137  -75.04292 1.000 15.52461 ? 139 TYR B CG  1 
ATOM   5188 C  CD1 . TYR B  1 139 ? 38.97552 16.65943  -74.52819 1.000 16.04630 ? 139 TYR B CD1 1 
ATOM   5189 C  CD2 . TYR B  1 139 ? 40.81673 15.65906  -75.65960 1.000 13.66247 ? 139 TYR B CD2 1 
ATOM   5190 C  CE1 . TYR B  1 139 ? 38.26784 15.47467  -74.62311 1.000 15.98250 ? 139 TYR B CE1 1 
ATOM   5191 C  CE2 . TYR B  1 139 ? 40.11767 14.47235  -75.76025 1.000 13.47503 ? 139 TYR B CE2 1 
ATOM   5192 C  CZ  . TYR B  1 139 ? 38.84345 14.38522  -75.24073 1.000 11.49626 ? 139 TYR B CZ  1 
ATOM   5193 O  OH  . TYR B  1 139 ? 38.14320 13.20440  -75.33821 1.000 8.16577  ? 139 TYR B OH  1 
ATOM   5194 N  N   . PRO B  1 140 ? 40.86458 21.55892  -75.73976 1.000 18.59327 ? 140 PRO B N   1 
ATOM   5195 C  CA  . PRO B  1 140 ? 41.68670 22.77725  -75.65615 1.000 13.79479 ? 140 PRO B CA  1 
ATOM   5196 C  C   . PRO B  1 140 ? 42.53602 22.85720  -74.40086 1.000 19.19158 ? 140 PRO B C   1 
ATOM   5197 O  O   . PRO B  1 140 ? 43.55217 23.56356  -74.41270 1.000 18.86257 ? 140 PRO B O   1 
ATOM   5198 C  CB  . PRO B  1 140 ? 40.64793 23.90695  -75.69489 1.000 14.78488 ? 140 PRO B CB  1 
ATOM   5199 C  CG  . PRO B  1 140 ? 39.42723 23.28603  -76.30434 1.000 14.95405 ? 140 PRO B CG  1 
ATOM   5200 C  CD  . PRO B  1 140 ? 39.42883 21.86398  -75.84098 1.000 12.56137 ? 140 PRO B CD  1 
ATOM   5201 N  N   . ASN B  1 141 ? 42.15161 22.16592  -73.32512 1.000 17.00181 ? 141 ASN B N   1 
ATOM   5202 C  CA  . ASN B  1 141 ? 42.91739 22.14479  -72.07681 1.000 17.38954 ? 141 ASN B CA  1 
ATOM   5203 C  C   . ASN B  1 141 ? 43.15459 23.55376  -71.53764 1.000 19.81317 ? 141 ASN B C   1 
ATOM   5204 O  O   . ASN B  1 141 ? 44.22803 23.86888  -71.01991 1.000 24.35150 ? 141 ASN B O   1 
ATOM   5205 C  CB  . ASN B  1 141 ? 44.24258 21.40154  -72.25260 1.000 18.43555 ? 141 ASN B CB  1 
ATOM   5206 C  CG  . ASN B  1 141 ? 44.04913 19.91611  -72.48209 1.000 22.12860 ? 141 ASN B CG  1 
ATOM   5207 O  OD1 . ASN B  1 141 ? 43.30908 19.25206  -71.75409 1.000 16.62529 ? 141 ASN B OD1 1 
ATOM   5208 N  ND2 . ASN B  1 141 ? 44.71071 19.38692  -73.50284 1.000 20.30847 ? 141 ASN B ND2 1 
ATOM   5209 N  N   . GLU B  1 142 ? 42.14406 24.40942  -71.65877 1.000 24.69468 ? 142 GLU B N   1 
ATOM   5210 C  CA  . GLU B  1 142 ? 42.20691 25.75559  -71.09461 1.000 20.12699 ? 142 GLU B CA  1 
ATOM   5211 C  C   . GLU B  1 142 ? 41.69201 25.77269  -69.65585 1.000 19.63256 ? 142 GLU B C   1 
ATOM   5212 O  O   . GLU B  1 142 ? 40.78972 26.52651  -69.30128 1.000 25.57928 ? 142 GLU B O   1 
ATOM   5213 C  CB  . GLU B  1 142 ? 41.42995 26.73180  -71.97092 1.000 17.60497 ? 142 GLU B CB  1 
ATOM   5214 C  CG  . GLU B  1 142 ? 41.94766 26.83943  -73.39577 1.000 16.96218 ? 142 GLU B CG  1 
ATOM   5215 C  CD  . GLU B  1 142 ? 43.32919 27.47132  -73.47789 1.000 25.87983 ? 142 GLU B CD  1 
ATOM   5216 O  OE1 . GLU B  1 142 ? 43.76274 28.11405  -72.49714 1.000 23.22347 ? 142 GLU B OE1 1 
ATOM   5217 O  OE2 . GLU B  1 142 ? 43.98568 27.32797  -74.53058 1.000 27.88651 ? 142 GLU B OE2 1 
ATOM   5218 N  N   . GLN B  1 143 ? 42.27620 24.91912  -68.81844 1.000 21.48879 ? 143 GLN B N   1 
ATOM   5219 C  CA  . GLN B  1 143 ? 41.92110 24.83064  -67.40790 1.000 21.17872 ? 143 GLN B CA  1 
ATOM   5220 C  C   . GLN B  1 143 ? 43.18316 24.57321  -66.59776 1.000 17.79959 ? 143 GLN B C   1 
ATOM   5221 O  O   . GLN B  1 143 ? 44.20330 24.12836  -67.12840 1.000 14.54031 ? 143 GLN B O   1 
ATOM   5222 C  CB  . GLN B  1 143 ? 40.88568 23.72715  -67.14595 1.000 19.92918 ? 143 GLN B CB  1 
ATOM   5223 C  CG  . GLN B  1 143 ? 41.30846 22.34953  -67.62703 1.000 18.10685 ? 143 GLN B CG  1 
ATOM   5224 C  CD  . GLN B  1 143 ? 40.22783 21.30322  -67.42900 1.000 18.52325 ? 143 GLN B CD  1 
ATOM   5225 O  OE1 . GLN B  1 143 ? 39.69466 20.75645  -68.39296 1.000 16.62346 ? 143 GLN B OE1 1 
ATOM   5226 N  NE2 . GLN B  1 143 ? 39.90024 21.01926  -66.17444 1.000 19.84540 ? 143 GLN B NE2 1 
ATOM   5227 N  N   . ASP B  1 144 ? 43.10337 24.86044  -65.30051 1.000 20.10322 ? 144 ASP B N   1 
ATOM   5228 C  CA  . ASP B  1 144 ? 44.26204 24.73353  -64.42900 1.000 18.64161 ? 144 ASP B CA  1 
ATOM   5229 C  C   . ASP B  1 144 ? 44.65349 23.26814  -64.24984 1.000 18.98980 ? 144 ASP B C   1 
ATOM   5230 O  O   . ASP B  1 144 ? 43.89259 22.34753  -64.56171 1.000 19.85268 ? 144 ASP B O   1 
ATOM   5231 C  CB  . ASP B  1 144 ? 43.98220 25.37146  -63.06836 1.000 24.09804 ? 144 ASP B CB  1 
ATOM   5232 C  CG  . ASP B  1 144 ? 43.68418 26.85680  -63.16952 1.000 30.35746 ? 144 ASP B CG  1 
ATOM   5233 O  OD1 . ASP B  1 144 ? 44.17252 27.50216  -64.12252 1.000 18.03593 ? 144 ASP B OD1 1 
ATOM   5234 O  OD2 . ASP B  1 144 ? 42.96377 27.37972  -62.29248 1.000 28.15497 ? 144 ASP B OD2 1 
ATOM   5235 N  N   . ALA B  1 145 ? 45.86488 23.06252  -63.73529 1.000 20.37810 ? 145 ALA B N   1 
ATOM   5236 C  CA  . ALA B  1 145 ? 46.37618 21.71316  -63.53602 1.000 21.47566 ? 145 ALA B CA  1 
ATOM   5237 C  C   . ALA B  1 145 ? 45.50815 20.94455  -62.55036 1.000 16.05183 ? 145 ALA B C   1 
ATOM   5238 O  O   . ALA B  1 145 ? 45.11267 21.46697  -61.50484 1.000 20.00785 ? 145 ALA B O   1 
ATOM   5239 C  CB  . ALA B  1 145 ? 47.81602 21.75768  -63.02897 1.000 14.60107 ? 145 ALA B CB  1 
ATOM   5240 N  N   . THR B  1 146 ? 45.22201 19.69186  -62.88885 1.000 14.00546 ? 146 THR B N   1 
ATOM   5241 C  CA  . THR B  1 146 ? 44.42504 18.81715  -62.04041 1.000 14.43266 ? 146 THR B CA  1 
ATOM   5242 C  C   . THR B  1 146 ? 44.60414 17.38898  -62.53527 1.000 15.17743 ? 146 THR B C   1 
ATOM   5243 O  O   . THR B  1 146 ? 45.31533 17.13246  -63.51022 1.000 14.52820 ? 146 THR B O   1 
ATOM   5244 C  CB  . THR B  1 146 ? 42.94748 19.22128  -62.04532 1.000 12.66864 ? 146 THR B CB  1 
ATOM   5245 O  OG1 . THR B  1 146 ? 42.23009 18.41949  -61.09988 1.000 18.22408 ? 146 THR B OG1 1 
ATOM   5246 C  CG2 . THR B  1 146 ? 42.34538 19.02040  -63.42788 1.000 10.80612 ? 146 THR B CG2 1 
ATOM   5247 N  N   . ALA B  1 147 ? 43.94751 16.45764  -61.85231 1.000 16.11976 ? 147 ALA B N   1 
ATOM   5248 C  CA  . ALA B  1 147 ? 43.94868 15.04856  -62.22615 1.000 15.08255 ? 147 ALA B CA  1 
ATOM   5249 C  C   . ALA B  1 147 ? 42.57144 14.70412  -62.78025 1.000 17.41904 ? 147 ALA B C   1 
ATOM   5250 O  O   . ALA B  1 147 ? 41.58636 14.67475  -62.03493 1.000 21.00923 ? 147 ALA B O   1 
ATOM   5251 C  CB  . ALA B  1 147 ? 44.30191 14.16357  -61.03269 1.000 15.02466 ? 147 ALA B CB  1 
ATOM   5252 N  N   . LEU B  1 148 ? 42.50154 14.45830  -64.08434 1.000 12.60289 ? 148 LEU B N   1 
ATOM   5253 C  CA  . LEU B  1 148 ? 41.28131 14.00443  -64.72729 1.000 11.94074 ? 148 LEU B CA  1 
ATOM   5254 C  C   . LEU B  1 148 ? 41.38662 12.51463  -65.02954 1.000 13.19107 ? 148 LEU B C   1 
ATOM   5255 O  O   . LEU B  1 148 ? 42.35999 11.84556  -64.66997 1.000 12.63299 ? 148 LEU B O   1 
ATOM   5256 C  CB  . LEU B  1 148 ? 41.01504 14.79858  -66.00865 1.000 12.14455 ? 148 LEU B CB  1 
ATOM   5257 C  CG  . LEU B  1 148 ? 40.92620 16.31963  -65.89062 1.000 9.17475  ? 148 LEU B CG  1 
ATOM   5258 C  CD1 . LEU B  1 148 ? 40.68218 16.94852  -67.24947 1.000 14.25226 ? 148 LEU B CD1 1 
ATOM   5259 C  CD2 . LEU B  1 148 ? 39.84340 16.72838  -64.90436 1.000 14.68422 ? 148 LEU B CD2 1 
ATOM   5260 N  N   . TRP B  1 149 ? 40.37275 11.99075  -65.71195 1.000 11.12070 ? 149 TRP B N   1 
ATOM   5261 C  CA  . TRP B  1 149 ? 40.39599 10.60932  -66.16393 1.000 9.87197  ? 149 TRP B CA  1 
ATOM   5262 C  C   . TRP B  1 149 ? 39.33375 10.43636  -67.23650 1.000 10.39660 ? 149 TRP B C   1 
ATOM   5263 O  O   . TRP B  1 149 ? 38.33680 11.16178  -67.26229 1.000 12.00261 ? 149 TRP B O   1 
ATOM   5264 C  CB  . TRP B  1 149 ? 40.17768 9.62687   -65.00431 1.000 9.51348  ? 149 TRP B CB  1 
ATOM   5265 C  CG  . TRP B  1 149 ? 38.81970 9.67157   -64.37007 1.000 8.61176  ? 149 TRP B CG  1 
ATOM   5266 C  CD1 . TRP B  1 149 ? 38.23040 10.74260  -63.76397 1.000 10.03933 ? 149 TRP B CD1 1 
ATOM   5267 C  CD2 . TRP B  1 149 ? 37.89548 8.58290   -64.24591 1.000 9.80610  ? 149 TRP B CD2 1 
ATOM   5268 N  NE1 . TRP B  1 149 ? 36.99067 10.39423  -63.28588 1.000 8.88480  ? 149 TRP B NE1 1 
ATOM   5269 C  CE2 . TRP B  1 149 ? 36.76171 9.07314   -63.56727 1.000 10.55894 ? 149 TRP B CE2 1 
ATOM   5270 C  CE3 . TRP B  1 149 ? 37.91360 7.24320   -64.64862 1.000 11.02599 ? 149 TRP B CE3 1 
ATOM   5271 C  CZ2 . TRP B  1 149 ? 35.65668 8.27192   -63.28232 1.000 10.02255 ? 149 TRP B CZ2 1 
ATOM   5272 C  CZ3 . TRP B  1 149 ? 36.81386 6.44898   -64.36515 1.000 8.92617  ? 149 TRP B CZ3 1 
ATOM   5273 C  CH2 . TRP B  1 149 ? 35.70219 6.96621   -63.68813 1.000 10.56386 ? 149 TRP B CH2 1 
ATOM   5274 N  N   . TYR B  1 150 ? 39.56696 9.47930   -68.12904 1.000 10.60500 ? 150 TYR B N   1 
ATOM   5275 C  CA  . TYR B  1 150 ? 38.66370 9.21335   -69.23597 1.000 11.13213 ? 150 TYR B CA  1 
ATOM   5276 C  C   . TYR B  1 150 ? 38.09596 7.80628   -69.11774 1.000 11.97843 ? 150 TYR B C   1 
ATOM   5277 O  O   . TYR B  1 150 ? 38.76899 6.88042   -68.65390 1.000 10.92358 ? 150 TYR B O   1 
ATOM   5278 C  CB  . TYR B  1 150 ? 39.36746 9.39228   -70.59033 1.000 13.06085 ? 150 TYR B CB  1 
ATOM   5279 C  CG  . TYR B  1 150 ? 40.55165 8.47655   -70.82102 1.000 12.70039 ? 150 TYR B CG  1 
ATOM   5280 C  CD1 . TYR B  1 150 ? 41.79699 8.76908   -70.28269 1.000 11.93042 ? 150 TYR B CD1 1 
ATOM   5281 C  CD2 . TYR B  1 150 ? 40.42697 7.33087   -71.59512 1.000 14.08755 ? 150 TYR B CD2 1 
ATOM   5282 C  CE1 . TYR B  1 150 ? 42.88192 7.94112   -70.49901 1.000 15.47034 ? 150 TYR B CE1 1 
ATOM   5283 C  CE2 . TYR B  1 150 ? 41.50529 6.49777   -71.81675 1.000 18.07720 ? 150 TYR B CE2 1 
ATOM   5284 C  CZ  . TYR B  1 150 ? 42.73064 6.80658   -71.26590 1.000 19.01544 ? 150 TYR B CZ  1 
ATOM   5285 O  OH  . TYR B  1 150 ? 43.80820 5.97742   -71.48349 1.000 16.26006 ? 150 TYR B OH  1 
ATOM   5286 N  N   . HIS B  1 151 ? 36.84454 7.65835   -69.54062 1.000 10.19444 ? 151 HIS B N   1 
ATOM   5287 C  CA  . HIS B  1 151 ? 36.14839 6.38407   -69.44551 1.000 12.62343 ? 151 HIS B CA  1 
ATOM   5288 C  C   . HIS B  1 151 ? 35.00491 6.38378   -70.44749 1.000 14.38001 ? 151 HIS B C   1 
ATOM   5289 O  O   . HIS B  1 151 ? 34.62370 7.42546   -70.98655 1.000 12.52832 ? 151 HIS B O   1 
ATOM   5290 C  CB  . HIS B  1 151 ? 35.63340 6.13197   -68.02515 1.000 12.19120 ? 151 HIS B CB  1 
ATOM   5291 C  CG  . HIS B  1 151 ? 34.67521 7.17349   -67.53719 1.000 14.66834 ? 151 HIS B CG  1 
ATOM   5292 N  ND1 . HIS B  1 151 ? 33.36722 7.24258   -67.96627 1.000 15.21906 ? 151 HIS B ND1 1 
ATOM   5293 C  CD2 . HIS B  1 151 ? 34.83723 8.19221   -66.66024 1.000 12.31161 ? 151 HIS B CD2 1 
ATOM   5294 C  CE1 . HIS B  1 151 ? 32.76421 8.25679   -67.37239 1.000 12.87942 ? 151 HIS B CE1 1 
ATOM   5295 N  NE2 . HIS B  1 151 ? 33.63382 8.84850   -66.57378 1.000 11.87211 ? 151 HIS B NE2 1 
ATOM   5296 N  N   . ASP B  1 152 ? 34.45784 5.19551   -70.68638 1.000 15.93020 ? 152 ASP B N   1 
ATOM   5297 C  CA  . ASP B  1 152 ? 33.35380 5.06407   -71.62287 1.000 17.51807 ? 152 ASP B CA  1 
ATOM   5298 C  C   . ASP B  1 152 ? 32.09524 5.71666   -71.06379 1.000 17.26849 ? 152 ASP B C   1 
ATOM   5299 O  O   . ASP B  1 152 ? 31.88462 5.77894   -69.84945 1.000 15.66522 ? 152 ASP B O   1 
ATOM   5300 C  CB  . ASP B  1 152 ? 33.08253 3.59503   -71.93295 1.000 18.15566 ? 152 ASP B CB  1 
ATOM   5301 C  CG  . ASP B  1 152 ? 32.10765 3.41860   -73.07458 1.000 15.54509 ? 152 ASP B CG  1 
ATOM   5302 O  OD1 . ASP B  1 152 ? 32.54735 3.48308   -74.24083 1.000 15.81215 ? 152 ASP B OD1 1 
ATOM   5303 O  OD2 . ASP B  1 152 ? 30.90208 3.23278   -72.80690 1.000 17.21405 ? 152 ASP B OD2 1 
ATOM   5304 N  N   . HIS B  1 153 ? 31.24649 6.20381   -71.97351 1.000 18.02150 ? 153 HIS B N   1 
ATOM   5305 C  CA  . HIS B  1 153 ? 30.04510 6.92075   -71.56586 1.000 15.64473 ? 153 HIS B CA  1 
ATOM   5306 C  C   . HIS B  1 153 ? 28.82909 6.53938   -72.40498 1.000 13.91719 ? 153 HIS B C   1 
ATOM   5307 O  O   . HIS B  1 153 ? 27.84374 7.28624   -72.41993 1.000 12.38919 ? 153 HIS B O   1 
ATOM   5308 C  CB  . HIS B  1 153 ? 30.27411 8.43358   -71.64737 1.000 11.62474 ? 153 HIS B CB  1 
ATOM   5309 C  CG  . HIS B  1 153 ? 29.48728 9.21919   -70.64543 1.000 16.94746 ? 153 HIS B CG  1 
ATOM   5310 N  ND1 . HIS B  1 153 ? 28.11927 9.10779   -70.51934 1.000 16.49922 ? 153 HIS B ND1 1 
ATOM   5311 C  CD2 . HIS B  1 153 ? 29.87709 10.13129  -69.72362 1.000 12.26011 ? 153 HIS B CD2 1 
ATOM   5312 C  CE1 . HIS B  1 153 ? 27.70070 9.91652   -69.56224 1.000 17.71265 ? 153 HIS B CE1 1 
ATOM   5313 N  NE2 . HIS B  1 153 ? 28.74740 10.54928  -69.06356 1.000 12.45069 ? 153 HIS B NE2 1 
ATOM   5314 N  N   . ALA B  1 154 ? 28.87230 5.40502   -73.10265 1.000 15.54945 ? 154 ALA B N   1 
ATOM   5315 C  CA  . ALA B  1 154 ? 27.76523 5.01321   -73.96552 1.000 15.91654 ? 154 ALA B CA  1 
ATOM   5316 C  C   . ALA B  1 154 ? 26.49443 4.81401   -73.15032 1.000 14.22667 ? 154 ALA B C   1 
ATOM   5317 O  O   . ALA B  1 154 ? 26.53127 4.31577   -72.02195 1.000 16.56672 ? 154 ALA B O   1 
ATOM   5318 C  CB  . ALA B  1 154 ? 28.11171 3.73372   -74.72602 1.000 13.66801 ? 154 ALA B CB  1 
ATOM   5319 N  N   . MET B  1 155 ? 25.36376 5.20750   -73.72949 1.000 10.68613 ? 155 MET B N   1 
ATOM   5320 C  CA  . MET B  1 155 ? 24.11156 5.18805   -72.99054 1.000 19.28356 ? 155 MET B CA  1 
ATOM   5321 C  C   . MET B  1 155 ? 23.65949 3.75811   -72.71888 1.000 20.65597 ? 155 MET B C   1 
ATOM   5322 O  O   . MET B  1 155 ? 23.89665 2.84421   -73.51403 1.000 26.95239 ? 155 MET B O   1 
ATOM   5323 C  CB  . MET B  1 155 ? 23.02166 5.94388   -73.75091 1.000 22.67586 ? 155 MET B CB  1 
ATOM   5324 C  CG  . MET B  1 155 ? 21.84160 6.33624   -72.87336 1.000 14.98299 ? 155 MET B CG  1 
ATOM   5325 S  SD  . MET B  1 155 ? 20.64874 7.40508   -73.69166 1.000 46.08135 ? 155 MET B SD  1 
ATOM   5326 C  CE  . MET B  1 155 ? 19.81090 6.23948   -74.76313 1.000 32.73993 ? 155 MET B CE  1 
ATOM   5327 N  N   . ALA B  1 156 ? 23.02936 3.57576   -71.55515 1.000 20.17439 ? 156 ALA B N   1 
ATOM   5328 C  CA  . ALA B  1 156 ? 22.39715 2.32838   -71.13414 1.000 20.67599 ? 156 ALA B CA  1 
ATOM   5329 C  C   . ALA B  1 156 ? 23.39855 1.22982   -70.78879 1.000 16.24839 ? 156 ALA B C   1 
ATOM   5330 O  O   . ALA B  1 156 ? 23.02451 0.23427   -70.16145 1.000 14.96007 ? 156 ALA B O   1 
ATOM   5331 C  CB  . ALA B  1 156 ? 21.42136 1.82996   -72.20559 1.000 15.72432 ? 156 ALA B CB  1 
ATOM   5332 N  N   . ILE B  1 157 ? 24.66467 1.38683   -71.17838 1.000 15.43121 ? 157 ILE B N   1 
ATOM   5333 C  CA  . ILE B  1 157 ? 25.66808 0.36213   -70.90125 1.000 17.39993 ? 157 ILE B CA  1 
ATOM   5334 C  C   . ILE B  1 157 ? 26.94982 0.98842   -70.36340 1.000 19.61876 ? 157 ILE B C   1 
ATOM   5335 O  O   . ILE B  1 157 ? 28.03651 0.41265   -70.49758 1.000 18.71265 ? 157 ILE B O   1 
ATOM   5336 C  CB  . ILE B  1 157 ? 25.96738 -0.48563  -72.15271 1.000 15.21561 ? 157 ILE B CB  1 
ATOM   5337 C  CG1 . ILE B  1 157 ? 26.47107 0.39741   -73.29629 1.000 14.74649 ? 157 ILE B CG1 1 
ATOM   5338 C  CG2 . ILE B  1 157 ? 24.74015 -1.28403  -72.57236 1.000 14.00959 ? 157 ILE B CG2 1 
ATOM   5339 C  CD1 . ILE B  1 157 ? 27.04289 -0.38472  -74.45692 1.000 16.39726 ? 157 ILE B CD1 1 
ATOM   5340 N  N   . THR B  1 158 ? 26.83689 2.16670   -69.74546 1.000 15.51372 ? 158 THR B N   1 
ATOM   5341 C  CA  . THR B  1 158 ? 28.01411 2.79076   -69.14893 1.000 17.58477 ? 158 THR B CA  1 
ATOM   5342 C  C   . THR B  1 158 ? 28.53634 1.98070   -67.96685 1.000 23.20919 ? 158 THR B C   1 
ATOM   5343 O  O   . THR B  1 158 ? 29.75317 1.91221   -67.75105 1.000 16.62641 ? 158 THR B O   1 
ATOM   5344 C  CB  . THR B  1 158 ? 27.69223 4.22569   -68.72222 1.000 16.03085 ? 158 THR B CB  1 
ATOM   5345 O  OG1 . THR B  1 158 ? 27.32565 4.99488   -69.87414 1.000 15.36094 ? 158 THR B OG1 1 
ATOM   5346 C  CG2 . THR B  1 158 ? 28.89631 4.87938   -68.05830 1.000 13.69833 ? 158 THR B CG2 1 
ATOM   5347 N  N   . ARG B  1 159 ? 27.64033 1.34508   -67.20641 1.000 16.97923 ? 159 ARG B N   1 
ATOM   5348 C  CA  . ARG B  1 159 ? 28.07767 0.52657   -66.08102 1.000 15.96266 ? 159 ARG B CA  1 
ATOM   5349 C  C   . ARG B  1 159 ? 28.86287 -0.69289  -66.54452 1.000 17.14464 ? 159 ARG B C   1 
ATOM   5350 O  O   . ARG B  1 159 ? 29.71829 -1.19362  -65.80643 1.000 15.43250 ? 159 ARG B O   1 
ATOM   5351 C  CB  . ARG B  1 159 ? 26.87251 0.09462   -65.24287 1.000 17.21955 ? 159 ARG B CB  1 
ATOM   5352 C  CG  . ARG B  1 159 ? 26.04580 -1.01395  -65.86895 1.000 18.12897 ? 159 ARG B CG  1 
ATOM   5353 C  CD  . ARG B  1 159 ? 24.64899 -1.08014  -65.28307 1.000 18.55849 ? 159 ARG B CD  1 
ATOM   5354 N  NE  . ARG B  1 159 ? 23.88428 -2.17624  -65.86499 1.000 20.74517 ? 159 ARG B NE  1 
ATOM   5355 C  CZ  . ARG B  1 159 ? 23.23741 -2.10505  -67.01972 1.000 14.72252 ? 159 ARG B CZ  1 
ATOM   5356 N  NH1 . ARG B  1 159 ? 23.23219 -0.99644  -67.74096 1.000 17.35744 ? 159 ARG B NH1 1 
ATOM   5357 N  NH2 . ARG B  1 159 ? 22.58181 -3.17348  -67.46299 1.000 13.63528 ? 159 ARG B NH2 1 
ATOM   5358 N  N   . LEU B  1 160 ? 28.59802 -1.17567  -67.75804 1.000 22.52600 ? 160 LEU B N   1 
ATOM   5359 C  CA  . LEU B  1 160 ? 29.25242 -2.37312  -68.26961 1.000 22.39699 ? 160 LEU B CA  1 
ATOM   5360 C  C   . LEU B  1 160 ? 30.59889 -2.06913  -68.91287 1.000 17.29619 ? 160 LEU B C   1 
ATOM   5361 O  O   . LEU B  1 160 ? 31.57765 -2.77892  -68.65947 1.000 16.68385 ? 160 LEU B O   1 
ATOM   5362 C  CB  . LEU B  1 160 ? 28.34205 -3.07705  -69.27945 1.000 18.47375 ? 160 LEU B CB  1 
ATOM   5363 C  CG  . LEU B  1 160 ? 26.95972 -3.47538  -68.76098 1.000 16.15913 ? 160 LEU B CG  1 
ATOM   5364 C  CD1 . LEU B  1 160 ? 26.13793 -4.12074  -69.86186 1.000 12.22118 ? 160 LEU B CD1 1 
ATOM   5365 C  CD2 . LEU B  1 160 ? 27.08662 -4.40558  -67.56675 1.000 16.72199 ? 160 LEU B CD2 1 
ATOM   5366 N  N   . ASN B  1 161 ? 30.66890 -1.02452  -69.74147 1.000 19.26547 ? 161 ASN B N   1 
ATOM   5367 C  CA  . ASN B  1 161 ? 31.91702 -0.71377  -70.43085 1.000 17.80123 ? 161 ASN B CA  1 
ATOM   5368 C  C   . ASN B  1 161 ? 32.98900 -0.24297  -69.45661 1.000 14.56194 ? 161 ASN B C   1 
ATOM   5369 O  O   . ASN B  1 161 ? 34.16283 -0.60254  -69.59835 1.000 18.33776 ? 161 ASN B O   1 
ATOM   5370 C  CB  . ASN B  1 161 ? 31.67186 0.33624   -71.51357 1.000 17.64546 ? 161 ASN B CB  1 
ATOM   5371 C  CG  . ASN B  1 161 ? 30.88903 -0.21225  -72.68791 1.000 15.60509 ? 161 ASN B CG  1 
ATOM   5372 O  OD1 . ASN B  1 161 ? 30.80855 -1.42509  -72.88022 1.000 17.99894 ? 161 ASN B OD1 1 
ATOM   5373 N  ND2 . ASN B  1 161 ? 30.31418 0.67909   -73.48616 1.000 18.75146 ? 161 ASN B ND2 1 
ATOM   5374 N  N   . VAL B  1 162 ? 32.60936 0.56536   -68.46581 1.000 16.79685 ? 162 VAL B N   1 
ATOM   5375 C  CA  . VAL B  1 162 ? 33.57158 0.99401   -67.45598 1.000 14.95932 ? 162 VAL B CA  1 
ATOM   5376 C  C   . VAL B  1 162 ? 34.03193 -0.19513  -66.62393 1.000 13.44151 ? 162 VAL B C   1 
ATOM   5377 O  O   . VAL B  1 162 ? 35.22677 -0.35172  -66.34405 1.000 18.74879 ? 162 VAL B O   1 
ATOM   5378 C  CB  . VAL B  1 162 ? 32.96377 2.10098   -66.57574 1.000 13.99923 ? 162 VAL B CB  1 
ATOM   5379 C  CG1 . VAL B  1 162 ? 33.89033 2.43140   -65.41638 1.000 8.84213  ? 162 VAL B CG1 1 
ATOM   5380 C  CG2 . VAL B  1 162 ? 32.67491 3.34261   -67.40506 1.000 15.78965 ? 162 VAL B CG2 1 
ATOM   5381 N  N   . TYR B  1 163 ? 33.09351 -1.05289  -66.21842 1.000 15.70480 ? 163 TYR B N   1 
ATOM   5382 C  CA  . TYR B  1 163 ? 33.45469 -2.24364  -65.45843 1.000 13.40638 ? 163 TYR B CA  1 
ATOM   5383 C  C   . TYR B  1 163 ? 34.31409 -3.19094  -66.28312 1.000 14.99029 ? 163 TYR B C   1 
ATOM   5384 O  O   . TYR B  1 163 ? 35.16977 -3.89212  -65.73103 1.000 15.86764 ? 163 TYR B O   1 
ATOM   5385 C  CB  . TYR B  1 163 ? 32.18934 -2.94929  -64.97305 1.000 13.99511 ? 163 TYR B CB  1 
ATOM   5386 C  CG  . TYR B  1 163 ? 32.43773 -4.09839  -64.02745 1.000 17.82041 ? 163 TYR B CG  1 
ATOM   5387 C  CD1 . TYR B  1 163 ? 32.91005 -3.87256  -62.74293 1.000 17.80306 ? 163 TYR B CD1 1 
ATOM   5388 C  CD2 . TYR B  1 163 ? 32.18185 -5.40861  -64.41214 1.000 15.59883 ? 163 TYR B CD2 1 
ATOM   5389 C  CE1 . TYR B  1 163 ? 33.13494 -4.91743  -61.87363 1.000 18.57037 ? 163 TYR B CE1 1 
ATOM   5390 C  CE2 . TYR B  1 163 ? 32.40147 -6.46108  -63.54630 1.000 17.61554 ? 163 TYR B CE2 1 
ATOM   5391 C  CZ  . TYR B  1 163 ? 32.87786 -6.20906  -62.27777 1.000 19.16055 ? 163 TYR B CZ  1 
ATOM   5392 O  OH  . TYR B  1 163 ? 33.10107 -7.25255  -61.40924 1.000 25.72820 ? 163 TYR B OH  1 
ATOM   5393 N  N   . ALA B  1 164 ? 34.11219 -3.21601  -67.60367 1.000 13.65629 ? 164 ALA B N   1 
ATOM   5394 C  CA  . ALA B  1 164 ? 34.91005 -4.07331  -68.47178 1.000 15.79104 ? 164 ALA B CA  1 
ATOM   5395 C  C   . ALA B  1 164 ? 36.37509 -3.66016  -68.51339 1.000 13.79815 ? 164 ALA B C   1 
ATOM   5396 O  O   . ALA B  1 164 ? 37.21412 -4.45334  -68.95042 1.000 16.90373 ? 164 ALA B O   1 
ATOM   5397 C  CB  . ALA B  1 164 ? 34.33190 -4.07485  -69.88642 1.000 18.53500 ? 164 ALA B CB  1 
ATOM   5398 N  N   . GLY B  1 165 ? 36.70007 -2.44496  -68.07791 1.000 16.71667 ? 165 GLY B N   1 
ATOM   5399 C  CA  . GLY B  1 165 ? 38.08158 -2.01309  -67.99740 1.000 19.35630 ? 165 GLY B CA  1 
ATOM   5400 C  C   . GLY B  1 165 ? 38.39528 -0.78134  -68.82093 1.000 18.24937 ? 165 GLY B C   1 
ATOM   5401 O  O   . GLY B  1 165 ? 39.56695 -0.46038  -69.04400 1.000 14.52758 ? 165 GLY B O   1 
ATOM   5402 N  N   . LEU B  1 166 ? 37.35852 -0.08251  -69.28238 1.000 15.00020 ? 166 LEU B N   1 
ATOM   5403 C  CA  . LEU B  1 166 ? 37.53945 1.10426   -70.12028 1.000 16.06926 ? 166 LEU B CA  1 
ATOM   5404 C  C   . LEU B  1 166 ? 37.67726 2.34623   -69.23698 1.000 17.68744 ? 166 LEU B C   1 
ATOM   5405 O  O   . LEU B  1 166 ? 36.80379 3.21286   -69.16715 1.000 10.35478 ? 166 LEU B O   1 
ATOM   5406 C  CB  . LEU B  1 166 ? 36.38896 1.23487   -71.10944 1.000 15.90138 ? 166 LEU B CB  1 
ATOM   5407 C  CG  . LEU B  1 166 ? 36.39346 0.21391   -72.24957 1.000 17.65831 ? 166 LEU B CG  1 
ATOM   5408 C  CD1 . LEU B  1 166 ? 35.08021 0.24171   -73.01309 1.000 15.10240 ? 166 LEU B CD1 1 
ATOM   5409 C  CD2 . LEU B  1 166 ? 37.56309 0.47313   -73.18605 1.000 14.55085 ? 166 LEU B CD2 1 
ATOM   5410 N  N   . VAL B  1 167 ? 38.81595 2.41091   -68.54523 1.000 18.13699 ? 167 VAL B N   1 
ATOM   5411 C  CA  . VAL B  1 167 ? 39.17672 3.55325   -67.71507 1.000 13.25640 ? 167 VAL B CA  1 
ATOM   5412 C  C   . VAL B  1 167 ? 40.65177 3.86194   -67.92771 1.000 14.99592 ? 167 VAL B C   1 
ATOM   5413 O  O   . VAL B  1 167 ? 41.45470 2.97675   -68.23861 1.000 18.60017 ? 167 VAL B O   1 
ATOM   5414 C  CB  . VAL B  1 167 ? 38.89280 3.31150   -66.21391 1.000 11.15793 ? 167 VAL B CB  1 
ATOM   5415 C  CG1 . VAL B  1 167 ? 37.40146 3.15541   -65.96359 1.000 12.86201 ? 167 VAL B CG1 1 
ATOM   5416 C  CG2 . VAL B  1 167 ? 39.65623 2.09536   -65.71377 1.000 13.96021 ? 167 VAL B CG2 1 
ATOM   5417 N  N   . GLY B  1 168 ? 41.00371 5.13307   -67.75549 1.000 10.68350 ? 168 GLY B N   1 
ATOM   5418 C  CA  . GLY B  1 168 ? 42.37811 5.57581   -67.89888 1.000 11.22009 ? 168 GLY B CA  1 
ATOM   5419 C  C   . GLY B  1 168 ? 42.54584 6.92776   -67.24664 1.000 12.56076 ? 168 GLY B C   1 
ATOM   5420 O  O   . GLY B  1 168 ? 41.57109 7.60353   -66.91140 1.000 10.83196 ? 168 GLY B O   1 
ATOM   5421 N  N   . LEU B  1 169 ? 43.80353 7.32141   -67.07489 1.000 9.83726  ? 169 LEU B N   1 
ATOM   5422 C  CA  . LEU B  1 169 ? 44.13825 8.55876   -66.38727 1.000 11.50482 ? 169 LEU B CA  1 
ATOM   5423 C  C   . LEU B  1 169 ? 44.52788 9.65111   -67.37739 1.000 15.01323 ? 169 LEU B C   1 
ATOM   5424 O  O   . LEU B  1 169 ? 44.92277 9.38655   -68.51524 1.000 17.82450 ? 169 LEU B O   1 
ATOM   5425 C  CB  . LEU B  1 169 ? 45.26759 8.32813   -65.38121 1.000 16.12160 ? 169 LEU B CB  1 
ATOM   5426 C  CG  . LEU B  1 169 ? 44.90488 7.37881   -64.23718 1.000 14.49445 ? 169 LEU B CG  1 
ATOM   5427 C  CD1 . LEU B  1 169 ? 46.08274 7.18385   -63.30444 1.000 13.49500 ? 169 LEU B CD1 1 
ATOM   5428 C  CD2 . LEU B  1 169 ? 43.69830 7.89882   -63.47848 1.000 9.72869  ? 169 LEU B CD2 1 
ATOM   5429 N  N   . TYR B  1 170 ? 44.41468 10.89580  -66.91494 1.000 15.01337 ? 170 TYR B N   1 
ATOM   5430 C  CA  . TYR B  1 170 ? 44.62280 12.06696  -67.76462 1.000 15.51654 ? 170 TYR B CA  1 
ATOM   5431 C  C   . TYR B  1 170 ? 45.01797 13.21790  -66.84901 1.000 14.13021 ? 170 TYR B C   1 
ATOM   5432 O  O   . TYR B  1 170 ? 44.17277 13.73562  -66.11362 1.000 15.58546 ? 170 TYR B O   1 
ATOM   5433 C  CB  . TYR B  1 170 ? 43.35292 12.38560  -68.55096 1.000 13.41214 ? 170 TYR B CB  1 
ATOM   5434 C  CG  . TYR B  1 170 ? 43.44813 13.52608  -69.54874 1.000 15.92468 ? 170 TYR B CG  1 
ATOM   5435 C  CD1 . TYR B  1 170 ? 43.45024 14.85117  -69.12842 1.000 14.13715 ? 170 TYR B CD1 1 
ATOM   5436 C  CD2 . TYR B  1 170 ? 43.48137 13.27606  -70.91533 1.000 12.10064 ? 170 TYR B CD2 1 
ATOM   5437 C  CE1 . TYR B  1 170 ? 43.51849 15.89201  -70.03794 1.000 13.42888 ? 170 TYR B CE1 1 
ATOM   5438 C  CE2 . TYR B  1 170 ? 43.55041 14.31004  -71.83279 1.000 12.44173 ? 170 TYR B CE2 1 
ATOM   5439 C  CZ  . TYR B  1 170 ? 43.56664 15.61645  -71.38882 1.000 18.46558 ? 170 TYR B CZ  1 
ATOM   5440 O  OH  . TYR B  1 170 ? 43.63096 16.65065  -72.29785 1.000 14.08906 ? 170 TYR B OH  1 
ATOM   5441 N  N   . PHE B  1 171 ? 46.28769 13.61031  -66.88687 1.000 14.90339 ? 171 PHE B N   1 
ATOM   5442 C  CA  . PHE B  1 171 ? 46.81131 14.65314  -66.01637 1.000 12.61171 ? 171 PHE B CA  1 
ATOM   5443 C  C   . PHE B  1 171 ? 47.05986 15.93216  -66.80432 1.000 15.07791 ? 171 PHE B C   1 
ATOM   5444 O  O   . PHE B  1 171 ? 47.57555 15.89311  -67.92606 1.000 15.96655 ? 171 PHE B O   1 
ATOM   5445 C  CB  . PHE B  1 171 ? 48.11023 14.20652  -65.34097 1.000 14.33753 ? 171 PHE B CB  1 
ATOM   5446 C  CG  . PHE B  1 171 ? 47.93309 13.07495  -64.37023 1.000 16.09029 ? 171 PHE B CG  1 
ATOM   5447 C  CD1 . PHE B  1 171 ? 47.61433 13.32407  -63.04537 1.000 15.44508 ? 171 PHE B CD1 1 
ATOM   5448 C  CD2 . PHE B  1 171 ? 48.09266 11.76327  -64.77997 1.000 14.02781 ? 171 PHE B CD2 1 
ATOM   5449 C  CE1 . PHE B  1 171 ? 47.45431 12.28554  -62.15012 1.000 14.09602 ? 171 PHE B CE1 1 
ATOM   5450 C  CE2 . PHE B  1 171 ? 47.93291 10.71985  -63.88917 1.000 16.82121 ? 171 PHE B CE2 1 
ATOM   5451 C  CZ  . PHE B  1 171 ? 47.61327 10.98181  -62.57271 1.000 17.00076 ? 171 PHE B CZ  1 
ATOM   5452 N  N   . ILE B  1 172 ? 46.68967 17.06295  -66.20794 1.000 12.23869 ? 172 ILE B N   1 
ATOM   5453 C  CA  . ILE B  1 172 ? 46.97023 18.38660  -66.75045 1.000 15.19935 ? 172 ILE B CA  1 
ATOM   5454 C  C   . ILE B  1 172 ? 47.98044 19.06547  -65.83591 1.000 17.34158 ? 172 ILE B C   1 
ATOM   5455 O  O   . ILE B  1 172 ? 47.88779 18.95538  -64.60770 1.000 14.88186 ? 172 ILE B O   1 
ATOM   5456 C  CB  . ILE B  1 172 ? 45.68440 19.22780  -66.88086 1.000 14.55873 ? 172 ILE B CB  1 
ATOM   5457 C  CG1 . ILE B  1 172 ? 44.65507 18.49941  -67.74772 1.000 12.56375 ? 172 ILE B CG1 1 
ATOM   5458 C  CG2 . ILE B  1 172 ? 45.99066 20.60275  -67.45516 1.000 12.71875 ? 172 ILE B CG2 1 
ATOM   5459 C  CD1 . ILE B  1 172 ? 43.37901 19.28138  -67.97146 1.000 9.84109  ? 172 ILE B CD1 1 
ATOM   5460 N  N   . ARG B  1 173 ? 48.94898 19.75956  -66.43286 1.000 20.52252 ? 173 ARG B N   1 
ATOM   5461 C  CA  . ARG B  1 173 ? 50.02155 20.40843  -65.69313 1.000 23.07323 ? 173 ARG B CA  1 
ATOM   5462 C  C   . ARG B  1 173 ? 49.96901 21.91891  -65.89671 1.000 21.63878 ? 173 ARG B C   1 
ATOM   5463 O  O   . ARG B  1 173 ? 49.50824 22.40739  -66.93335 1.000 25.15758 ? 173 ARG B O   1 
ATOM   5464 C  CB  . ARG B  1 173 ? 51.39184 19.86665  -66.12296 1.000 21.69638 ? 173 ARG B CB  1 
ATOM   5465 C  CG  . ARG B  1 173 ? 51.50702 18.34652  -66.07906 1.000 21.24716 ? 173 ARG B CG  1 
ATOM   5466 C  CD  . ARG B  1 173 ? 51.39589 17.81157  -64.66020 1.000 22.10804 ? 173 ARG B CD  1 
ATOM   5467 N  NE  . ARG B  1 173 ? 51.55522 16.36230  -64.60921 1.000 20.63902 ? 173 ARG B NE  1 
ATOM   5468 C  CZ  . ARG B  1 173 ? 51.60667 15.65294  -63.48961 1.000 18.55175 ? 173 ARG B CZ  1 
ATOM   5469 N  NH1 . ARG B  1 173 ? 51.52033 16.22946  -62.30117 1.000 12.73107 ? 173 ARG B NH1 1 
ATOM   5470 N  NH2 . ARG B  1 173 ? 51.75122 14.33240  -63.56398 1.000 13.69716 ? 173 ARG B NH2 1 
ATOM   5471 N  N   . ASP B  1 174 ? 50.44893 22.64905  -64.88813 1.000 24.37065 ? 174 ASP B N   1 
ATOM   5472 C  CA  . ASP B  1 174 ? 50.46880 24.10529  -64.86826 1.000 19.68740 ? 174 ASP B CA  1 
ATOM   5473 C  C   . ASP B  1 174 ? 51.87128 24.59212  -64.54698 1.000 24.70075 ? 174 ASP B C   1 
ATOM   5474 O  O   . ASP B  1 174 ? 52.68980 23.85737  -63.99256 1.000 27.60950 ? 174 ASP B O   1 
ATOM   5475 C  CB  . ASP B  1 174 ? 49.51224 24.67889  -63.81454 1.000 20.17106 ? 174 ASP B CB  1 
ATOM   5476 C  CG  . ASP B  1 174 ? 48.26589 25.25255  -64.41581 1.000 29.85548 ? 174 ASP B CG  1 
ATOM   5477 O  OD1 . ASP B  1 174 ? 48.04726 25.01814  -65.62027 1.000 35.60608 ? 174 ASP B OD1 1 
ATOM   5478 O  OD2 . ASP B  1 174 ? 47.51886 25.94267  -63.68824 1.000 29.80272 ? 174 ASP B OD2 1 
ATOM   5479 N  N   . ARG B  1 175 ? 52.14007 25.85740  -64.87212 1.000 24.37096 ? 175 ARG B N   1 
ATOM   5480 C  CA  . ARG B  1 175 ? 53.34702 26.47921  -64.33978 1.000 28.68627 ? 175 ARG B CA  1 
ATOM   5481 C  C   . ARG B  1 175 ? 53.19572 26.77726  -62.85723 1.000 27.27452 ? 175 ARG B C   1 
ATOM   5482 O  O   . ARG B  1 175 ? 54.19133 26.79733  -62.12683 1.000 23.55597 ? 175 ARG B O   1 
ATOM   5483 C  CB  . ARG B  1 175 ? 53.69310 27.75030  -65.11485 1.000 29.88875 ? 175 ARG B CB  1 
ATOM   5484 C  CG  . ARG B  1 175 ? 54.52267 27.46340  -66.34901 1.000 38.79066 ? 175 ARG B CG  1 
ATOM   5485 C  CD  . ARG B  1 175 ? 54.55080 28.62563  -67.32038 1.000 38.94088 ? 175 ARG B CD  1 
ATOM   5486 N  NE  . ARG B  1 175 ? 54.55538 28.13736  -68.69411 1.000 51.94918 ? 175 ARG B NE  1 
ATOM   5487 C  CZ  . ARG B  1 175 ? 53.73438 28.56063  -69.64497 1.000 46.59720 ? 175 ARG B CZ  1 
ATOM   5488 N  NH1 . ARG B  1 175 ? 52.88449 29.55200  -69.43281 1.000 47.43212 ? 175 ARG B NH1 1 
ATOM   5489 N  NH2 . ARG B  1 175 ? 53.77126 27.97828  -70.84051 1.000 41.70990 ? 175 ARG B NH2 1 
ATOM   5490 N  N   . GLU B  1 176 ? 51.96287 26.99458  -62.39704 1.000 25.68229 ? 176 GLU B N   1 
ATOM   5491 C  CA  . GLU B  1 176 ? 51.71498 27.17567  -60.97163 1.000 24.83365 ? 176 GLU B CA  1 
ATOM   5492 C  C   . GLU B  1 176 ? 51.98242 25.88883  -60.20093 1.000 24.49920 ? 176 GLU B C   1 
ATOM   5493 O  O   . GLU B  1 176 ? 52.66939 25.89985  -59.17276 1.000 22.21968 ? 176 GLU B O   1 
ATOM   5494 C  CB  . GLU B  1 176 ? 50.27736 27.64373  -60.75712 1.000 27.48681 ? 176 GLU B CB  1 
ATOM   5495 C  CG  . GLU B  1 176 ? 49.84957 27.70993  -59.30816 1.000 26.52611 ? 176 GLU B CG  1 
ATOM   5496 C  CD  . GLU B  1 176 ? 48.38006 28.03695  -59.16293 1.000 35.48043 ? 176 GLU B CD  1 
ATOM   5497 O  OE1 . GLU B  1 176 ? 47.55161 27.36375  -59.81247 1.000 32.15728 ? 176 GLU B OE1 1 
ATOM   5498 O  OE2 . GLU B  1 176 ? 48.05429 28.97638  -58.41044 1.000 38.93745 ? 176 GLU B OE2 1 
ATOM   5499 N  N   . GLU B  1 177 ? 51.43906 24.76673  -60.68142 1.000 26.50136 ? 177 GLU B N   1 
ATOM   5500 C  CA  . GLU B  1 177 ? 51.67046 23.49124  -60.01152 1.000 24.24184 ? 177 GLU B CA  1 
ATOM   5501 C  C   . GLU B  1 177 ? 53.14307 23.10872  -60.05410 1.000 22.13106 ? 177 GLU B C   1 
ATOM   5502 O  O   . GLU B  1 177 ? 53.67270 22.53948  -59.09286 1.000 27.00315 ? 177 GLU B O   1 
ATOM   5503 C  CB  . GLU B  1 177 ? 50.82010 22.39259  -60.64925 1.000 21.17180 ? 177 GLU B CB  1 
ATOM   5504 C  CG  . GLU B  1 177 ? 50.80307 21.09853  -59.84972 1.000 18.77348 ? 177 GLU B CG  1 
ATOM   5505 C  CD  . GLU B  1 177 ? 50.31977 19.91205  -60.65776 1.000 22.58258 ? 177 GLU B CD  1 
ATOM   5506 O  OE1 . GLU B  1 177 ? 51.03388 19.50177  -61.59656 1.000 24.39668 ? 177 GLU B OE1 1 
ATOM   5507 O  OE2 . GLU B  1 177 ? 49.22452 19.39133  -60.35652 1.000 18.55566 ? 177 GLU B OE2 1 
ATOM   5508 N  N   . ARG B  1 178 ? 53.82134 23.41149  -61.16358 1.000 26.57373 ? 178 ARG B N   1 
ATOM   5509 C  CA  . ARG B  1 178 ? 55.24215 23.10008  -61.26574 1.000 25.59955 ? 178 ARG B CA  1 
ATOM   5510 C  C   . ARG B  1 178 ? 56.08131 23.99532  -60.36452 1.000 25.67058 ? 178 ARG B C   1 
ATOM   5511 O  O   . ARG B  1 178 ? 57.08428 23.53815  -59.80732 1.000 19.64544 ? 178 ARG B O   1 
ATOM   5512 C  CB  . ARG B  1 178 ? 55.69843 23.21057  -62.71988 1.000 29.73386 ? 178 ARG B CB  1 
ATOM   5513 C  CG  . ARG B  1 178 ? 55.18023 22.07259  -63.58385 1.000 30.85323 ? 178 ARG B CG  1 
ATOM   5514 C  CD  . ARG B  1 178 ? 55.54786 22.23696  -65.05109 1.000 23.46752 ? 178 ARG B CD  1 
ATOM   5515 N  NE  . ARG B  1 178 ? 55.15106 21.06255  -65.81858 1.000 30.32483 ? 178 ARG B NE  1 
ATOM   5516 C  CZ  . ARG B  1 178 ? 55.83307 19.92589  -65.84125 1.000 30.86889 ? 178 ARG B CZ  1 
ATOM   5517 N  NH1 . ARG B  1 178 ? 56.95490 19.78047  -65.15480 1.000 36.77956 ? 178 ARG B NH1 1 
ATOM   5518 N  NH2 . ARG B  1 178 ? 55.37700 18.90878  -66.56675 1.000 31.79445 ? 178 ARG B NH2 1 
ATOM   5519 N  N   . SER B  1 179 ? 55.68316 25.25975  -60.19268 1.000 26.19870 ? 179 SER B N   1 
ATOM   5520 C  CA  . SER B  1 179 ? 56.40919 26.14281  -59.28528 1.000 19.54850 ? 179 SER B CA  1 
ATOM   5521 C  C   . SER B  1 179 ? 56.46082 25.56990  -57.87608 1.000 27.42073 ? 179 SER B C   1 
ATOM   5522 O  O   . SER B  1 179 ? 57.40478 25.84610  -57.12696 1.000 31.58170 ? 179 SER B O   1 
ATOM   5523 C  CB  . SER B  1 179 ? 55.76762 27.52867  -59.27072 1.000 17.11907 ? 179 SER B CB  1 
ATOM   5524 O  OG  . SER B  1 179 ? 54.49146 27.48892  -58.65914 1.000 31.13982 ? 179 SER B OG  1 
ATOM   5525 N  N   . LEU B  1 180 ? 55.46123 24.77610  -57.49990 1.000 27.05691 ? 180 LEU B N   1 
ATOM   5526 C  CA  . LEU B  1 180 ? 55.49750 24.03149  -56.24913 1.000 23.72140 ? 180 LEU B CA  1 
ATOM   5527 C  C   . LEU B  1 180 ? 56.41690 22.82943  -56.42182 1.000 30.58949 ? 180 LEU B C   1 
ATOM   5528 O  O   . LEU B  1 180 ? 56.21748 22.01529  -57.33080 1.000 41.35126 ? 180 LEU B O   1 
ATOM   5529 C  CB  . LEU B  1 180 ? 54.09261 23.58244  -55.85399 1.000 25.16488 ? 180 LEU B CB  1 
ATOM   5530 C  CG  . LEU B  1 180 ? 52.97915 24.62884  -55.94020 1.000 23.30231 ? 180 LEU B CG  1 
ATOM   5531 C  CD1 . LEU B  1 180 ? 51.62115 23.97099  -55.77135 1.000 17.85747 ? 180 LEU B CD1 1 
ATOM   5532 C  CD2 . LEU B  1 180 ? 53.18030 25.71813  -54.90111 1.000 20.61323 ? 180 LEU B CD2 1 
ATOM   5533 N  N   . ASN B  1 181 ? 57.42067 22.71401  -55.55216 1.000 25.51247 ? 181 ASN B N   1 
ATOM   5534 C  CA  . ASN B  1 181 ? 58.39765 21.62784  -55.63094 1.000 26.79663 ? 181 ASN B CA  1 
ATOM   5535 C  C   . ASN B  1 181 ? 57.79736 20.32680  -55.08679 1.000 25.56229 ? 181 ASN B C   1 
ATOM   5536 O  O   . ASN B  1 181 ? 58.29902 19.70799  -54.14834 1.000 29.00138 ? 181 ASN B O   1 
ATOM   5537 C  CB  . ASN B  1 181 ? 59.66800 22.01462  -54.88404 1.000 31.44997 ? 181 ASN B CB  1 
ATOM   5538 C  CG  . ASN B  1 181 ? 60.83261 21.09965  -55.19973 1.000 28.87530 ? 181 ASN B CG  1 
ATOM   5539 O  OD1 . ASN B  1 181 ? 60.99499 20.64866  -56.33419 1.000 27.87114 ? 181 ASN B OD1 1 
ATOM   5540 N  ND2 . ASN B  1 181 ? 61.65153 20.81915  -54.19357 1.000 31.19227 ? 181 ASN B ND2 1 
ATOM   5541 N  N   . LEU B  1 182 ? 56.69538 19.91518  -55.70956 1.000 19.91663 ? 182 LEU B N   1 
ATOM   5542 C  CA  . LEU B  1 182 ? 55.98201 18.72695  -55.27939 1.000 20.36145 ? 182 LEU B CA  1 
ATOM   5543 C  C   . LEU B  1 182 ? 56.75898 17.46636  -55.64981 1.000 18.37999 ? 182 LEU B C   1 
ATOM   5544 O  O   . LEU B  1 182 ? 57.56510 17.47318  -56.58332 1.000 23.60902 ? 182 LEU B O   1 
ATOM   5545 C  CB  . LEU B  1 182 ? 54.59411 18.68049  -55.91358 1.000 17.92197 ? 182 LEU B CB  1 
ATOM   5546 C  CG  . LEU B  1 182 ? 53.60381 19.77525  -55.51745 1.000 20.29629 ? 182 LEU B CG  1 
ATOM   5547 C  CD1 . LEU B  1 182 ? 52.29858 19.60662  -56.27896 1.000 17.72744 ? 182 LEU B CD1 1 
ATOM   5548 C  CD2 . LEU B  1 182 ? 53.35847 19.76603  -54.01560 1.000 18.35554 ? 182 LEU B CD2 1 
ATOM   5549 N  N   . PRO B  1 183 ? 56.54692 16.37605  -54.91356 1.000 16.07546 ? 183 PRO B N   1 
ATOM   5550 C  CA  . PRO B  1 183 ? 57.11136 15.08512  -55.32648 1.000 14.52025 ? 183 PRO B CA  1 
ATOM   5551 C  C   . PRO B  1 183 ? 56.68445 14.73432  -56.74421 1.000 17.54296 ? 183 PRO B C   1 
ATOM   5552 O  O   . PRO B  1 183 ? 55.49508 14.71627  -57.06855 1.000 16.85490 ? 183 PRO B O   1 
ATOM   5553 C  CB  . PRO B  1 183 ? 56.53570 14.10586  -54.29792 1.000 11.95430 ? 183 PRO B CB  1 
ATOM   5554 C  CG  . PRO B  1 183 ? 56.31774 14.94544  -53.08304 1.000 15.04363 ? 183 PRO B CG  1 
ATOM   5555 C  CD  . PRO B  1 183 ? 55.90971 16.30410  -53.58639 1.000 14.51252 ? 183 PRO B CD  1 
ATOM   5556 N  N   . LYS B  1 184 ? 57.67122 14.46660  -57.59424 1.000 20.51448 ? 184 LYS B N   1 
ATOM   5557 C  CA  . LYS B  1 184 ? 57.44508 14.21325  -59.00888 1.000 23.02193 ? 184 LYS B CA  1 
ATOM   5558 C  C   . LYS B  1 184 ? 58.16618 12.93429  -59.41751 1.000 18.12154 ? 184 LYS B C   1 
ATOM   5559 O  O   . LYS B  1 184 ? 58.84012 12.28740  -58.61091 1.000 22.65152 ? 184 LYS B O   1 
ATOM   5560 C  CB  . LYS B  1 184 ? 57.91038 15.40170  -59.85996 1.000 22.21880 ? 184 LYS B CB  1 
ATOM   5561 C  CG  . LYS B  1 184 ? 59.31036 15.89314  -59.52165 1.000 28.58821 ? 184 LYS B CG  1 
ATOM   5562 C  CD  . LYS B  1 184 ? 59.79219 16.93373  -60.52209 1.000 23.78038 ? 184 LYS B CD  1 
ATOM   5563 C  CE  . LYS B  1 184 ? 58.82611 18.10334  -60.61957 1.000 28.65060 ? 184 LYS B CE  1 
ATOM   5564 N  NZ  . LYS B  1 184 ? 58.69248 18.83419  -59.32875 1.000 31.71807 ? 184 LYS B NZ  1 
ATOM   5565 N  N   . GLY B  1 185 ? 58.01153 12.57005  -60.68880 1.000 16.17261 ? 185 GLY B N   1 
ATOM   5566 C  CA  . GLY B  1 185 ? 58.68933 11.39445  -61.20986 1.000 18.45498 ? 185 GLY B CA  1 
ATOM   5567 C  C   . GLY B  1 185 ? 58.13670 10.11578  -60.61283 1.000 20.57916 ? 185 GLY B C   1 
ATOM   5568 O  O   . GLY B  1 185 ? 56.92071 9.92028   -60.50880 1.000 27.24366 ? 185 GLY B O   1 
ATOM   5569 N  N   . GLU B  1 186 ? 59.04738 9.22400   -60.21548 1.000 26.83443 ? 186 GLU B N   1 
ATOM   5570 C  CA  . GLU B  1 186 ? 58.65531 7.98294   -59.55919 1.000 24.44791 ? 186 GLU B CA  1 
ATOM   5571 C  C   . GLU B  1 186 ? 58.07520 8.21310   -58.17179 1.000 22.29771 ? 186 GLU B C   1 
ATOM   5572 O  O   . GLU B  1 186 ? 57.52858 7.27397   -57.58365 1.000 20.33626 ? 186 GLU B O   1 
ATOM   5573 C  CB  . GLU B  1 186 ? 59.85223 7.03593   -59.45917 1.000 20.37037 ? 186 GLU B CB  1 
ATOM   5574 C  CG  . GLU B  1 186 ? 61.00309 7.58340   -58.62932 1.000 29.50831 ? 186 GLU B CG  1 
ATOM   5575 C  CD  . GLU B  1 186 ? 62.11767 6.57292   -58.43212 1.000 39.53333 ? 186 GLU B CD  1 
ATOM   5576 O  OE1 . GLU B  1 186 ? 61.84373 5.47443   -57.90330 1.000 40.24818 ? 186 GLU B OE1 1 
ATOM   5577 O  OE2 . GLU B  1 186 ? 63.26820 6.87578   -58.81276 1.000 45.79050 ? 186 GLU B OE2 1 
ATOM   5578 N  N   . TYR B  1 187 ? 58.18373 9.42528   -57.63747 1.000 20.29485 ? 187 TYR B N   1 
ATOM   5579 C  CA  . TYR B  1 187 ? 57.65354 9.74619   -56.32174 1.000 25.75734 ? 187 TYR B CA  1 
ATOM   5580 C  C   . TYR B  1 187 ? 56.25283 10.33775  -56.38416 1.000 22.30232 ? 187 TYR B C   1 
ATOM   5581 O  O   . TYR B  1 187 ? 55.68467 10.66684  -55.33701 1.000 20.50063 ? 187 TYR B O   1 
ATOM   5582 C  CB  . TYR B  1 187 ? 58.61528 10.69122  -55.59803 1.000 21.96029 ? 187 TYR B CB  1 
ATOM   5583 C  CG  . TYR B  1 187 ? 60.02850 10.15851  -55.61040 1.000 27.62044 ? 187 TYR B CG  1 
ATOM   5584 C  CD1 . TYR B  1 187 ? 60.36970 9.03335   -54.86978 1.000 28.83939 ? 187 TYR B CD1 1 
ATOM   5585 C  CD2 . TYR B  1 187 ? 61.01352 10.75756  -56.38440 1.000 25.72251 ? 187 TYR B CD2 1 
ATOM   5586 C  CE1 . TYR B  1 187 ? 61.65512 8.52907   -54.88636 1.000 25.04026 ? 187 TYR B CE1 1 
ATOM   5587 C  CE2 . TYR B  1 187 ? 62.30353 10.26114  -56.40577 1.000 28.49308 ? 187 TYR B CE2 1 
ATOM   5588 C  CZ  . TYR B  1 187 ? 62.61798 9.14656   -55.65511 1.000 29.12182 ? 187 TYR B CZ  1 
ATOM   5589 O  OH  . TYR B  1 187 ? 63.89944 8.64582   -55.67273 1.000 34.95742 ? 187 TYR B OH  1 
ATOM   5590 N  N   . GLU B  1 188 ? 55.69036 10.47972  -57.58135 1.000 20.01440 ? 188 GLU B N   1 
ATOM   5591 C  CA  . GLU B  1 188 ? 54.26697 10.72368  -57.76943 1.000 19.86944 ? 188 GLU B CA  1 
ATOM   5592 C  C   . GLU B  1 188 ? 53.64295 9.43578   -58.28744 1.000 18.87895 ? 188 GLU B C   1 
ATOM   5593 O  O   . GLU B  1 188 ? 53.96821 8.98651   -59.39171 1.000 21.51281 ? 188 GLU B O   1 
ATOM   5594 C  CB  . GLU B  1 188 ? 54.01235 11.87588  -58.74012 1.000 14.14790 ? 188 GLU B CB  1 
ATOM   5595 C  CG  . GLU B  1 188 ? 52.53891 12.05961  -59.07584 1.000 13.59368 ? 188 GLU B CG  1 
ATOM   5596 C  CD  . GLU B  1 188 ? 52.30157 13.11651  -60.13330 1.000 14.64703 ? 188 GLU B CD  1 
ATOM   5597 O  OE1 . GLU B  1 188 ? 53.04766 14.11716  -60.15861 1.000 23.54290 ? 188 GLU B OE1 1 
ATOM   5598 O  OE2 . GLU B  1 188 ? 51.37013 12.94227  -60.94473 1.000 18.95403 ? 188 GLU B OE2 1 
ATOM   5599 N  N   . ILE B  1 189 ? 52.76185 8.84266   -57.49091 1.000 18.75579 ? 189 ILE B N   1 
ATOM   5600 C  CA  . ILE B  1 189 ? 52.17247 7.54366   -57.78318 1.000 20.38691 ? 189 ILE B CA  1 
ATOM   5601 C  C   . ILE B  1 189 ? 50.66210 7.71346   -57.89106 1.000 21.68761 ? 189 ILE B C   1 
ATOM   5602 O  O   . ILE B  1 189 ? 50.01898 8.14013   -56.92827 1.000 25.10508 ? 189 ILE B O   1 
ATOM   5603 C  CB  . ILE B  1 189 ? 52.52109 6.49981   -56.70912 1.000 22.69740 ? 189 ILE B CB  1 
ATOM   5604 C  CG1 . ILE B  1 189 ? 54.02715 6.23214   -56.69504 1.000 20.92810 ? 189 ILE B CG1 1 
ATOM   5605 C  CG2 . ILE B  1 189 ? 51.73800 5.21700   -56.93872 1.000 16.74393 ? 189 ILE B CG2 1 
ATOM   5606 C  CD1 . ILE B  1 189 ? 54.47235 5.33264   -55.56621 1.000 20.60437 ? 189 ILE B CD1 1 
ATOM   5607 N  N   . PRO B  1 190 ? 50.05063 7.40070   -59.03043 1.000 19.99428 ? 190 PRO B N   1 
ATOM   5608 C  CA  . PRO B  1 190 ? 48.58869 7.45828   -59.12007 1.000 16.43469 ? 190 PRO B CA  1 
ATOM   5609 C  C   . PRO B  1 190 ? 47.95401 6.17159   -58.61522 1.000 16.66516 ? 190 PRO B C   1 
ATOM   5610 O  O   . PRO B  1 190 ? 48.42314 5.06685   -58.90042 1.000 21.97371 ? 190 PRO B O   1 
ATOM   5611 C  CB  . PRO B  1 190 ? 48.34157 7.65316   -60.61896 1.000 16.75040 ? 190 PRO B CB  1 
ATOM   5612 C  CG  . PRO B  1 190 ? 49.49249 6.95234   -61.26344 1.000 20.40623 ? 190 PRO B CG  1 
ATOM   5613 C  CD  . PRO B  1 190 ? 50.67551 7.11080   -60.33292 1.000 18.35806 ? 190 PRO B CD  1 
ATOM   5614 N  N   . LEU B  1 191 ? 46.87468 6.32345   -57.85264 1.000 18.51556 ? 191 LEU B N   1 
ATOM   5615 C  CA  . LEU B  1 191 ? 46.16999 5.19680   -57.24183 1.000 16.70744 ? 191 LEU B CA  1 
ATOM   5616 C  C   . LEU B  1 191 ? 44.75264 5.14376   -57.80656 1.000 16.95460 ? 191 LEU B C   1 
ATOM   5617 O  O   . LEU B  1 191 ? 43.82331 5.72234   -57.23734 1.000 15.93360 ? 191 LEU B O   1 
ATOM   5618 C  CB  . LEU B  1 191 ? 46.16113 5.31769   -55.71524 1.000 11.29749 ? 191 LEU B CB  1 
ATOM   5619 C  CG  . LEU B  1 191 ? 47.52516 5.31373   -55.02312 1.000 14.95609 ? 191 LEU B CG  1 
ATOM   5620 C  CD1 . LEU B  1 191 ? 47.36411 5.43582   -53.51582 1.000 15.06745 ? 191 LEU B CD1 1 
ATOM   5621 C  CD2 . LEU B  1 191 ? 48.30641 4.05912   -55.38273 1.000 18.64171 ? 191 LEU B CD2 1 
ATOM   5622 N  N   . LEU B  1 192 ? 44.59134 4.44657   -58.92966 1.000 15.66978 ? 192 LEU B N   1 
ATOM   5623 C  CA  . LEU B  1 192 ? 43.27344 4.21510   -59.51822 1.000 12.31490 ? 192 LEU B CA  1 
ATOM   5624 C  C   . LEU B  1 192 ? 42.66714 3.00346   -58.82159 1.000 14.65743 ? 192 LEU B C   1 
ATOM   5625 O  O   . LEU B  1 192 ? 43.00550 1.85848   -59.13054 1.000 17.87438 ? 192 LEU B O   1 
ATOM   5626 C  CB  . LEU B  1 192 ? 43.38428 4.00979   -61.02557 1.000 9.54990  ? 192 LEU B CB  1 
ATOM   5627 C  CG  . LEU B  1 192 ? 42.11368 4.10592   -61.87889 1.000 13.33209 ? 192 LEU B CG  1 
ATOM   5628 C  CD1 . LEU B  1 192 ? 42.47164 4.43230   -63.31841 1.000 15.10956 ? 192 LEU B CD1 1 
ATOM   5629 C  CD2 . LEU B  1 192 ? 41.29230 2.82580   -61.82516 1.000 12.68599 ? 192 LEU B CD2 1 
ATOM   5630 N  N   . ILE B  1 193 ? 41.76370 3.25408   -57.87739 1.000 15.75197 ? 193 ILE B N   1 
ATOM   5631 C  CA  . ILE B  1 193 ? 41.20459 2.21659   -57.01775 1.000 18.62554 ? 193 ILE B CA  1 
ATOM   5632 C  C   . ILE B  1 193 ? 39.85065 1.79017   -57.56736 1.000 16.07082 ? 193 ILE B C   1 
ATOM   5633 O  O   . ILE B  1 193 ? 39.02591 2.63545   -57.93601 1.000 17.11509 ? 193 ILE B O   1 
ATOM   5634 C  CB  . ILE B  1 193 ? 41.07873 2.71068   -55.56684 1.000 17.65709 ? 193 ILE B CB  1 
ATOM   5635 C  CG1 . ILE B  1 193 ? 42.40164 3.31842   -55.09766 1.000 12.93144 ? 193 ILE B CG1 1 
ATOM   5636 C  CG2 . ILE B  1 193 ? 40.66084 1.57292   -54.64965 1.000 19.11414 ? 193 ILE B CG2 1 
ATOM   5637 C  CD1 . ILE B  1 193 ? 42.36535 3.83121   -53.67534 1.000 15.77632 ? 193 ILE B CD1 1 
ATOM   5638 N  N   . GLN B  1 194 ? 39.62047 0.47900   -57.61907 1.000 19.72466 ? 194 GLN B N   1 
ATOM   5639 C  CA  . GLN B  1 194 ? 38.36442 -0.08649  -58.09029 1.000 20.50867 ? 194 GLN B CA  1 
ATOM   5640 C  C   . GLN B  1 194 ? 38.05292 -1.34521  -57.29331 1.000 23.62402 ? 194 GLN B C   1 
ATOM   5641 O  O   . GLN B  1 194 ? 38.89473 -1.86638  -56.55691 1.000 21.03376 ? 194 GLN B O   1 
ATOM   5642 C  CB  . GLN B  1 194 ? 38.41525 -0.41813  -59.58662 1.000 18.09710 ? 194 GLN B CB  1 
ATOM   5643 C  CG  . GLN B  1 194 ? 38.43196 0.78430   -60.50556 1.000 15.49134 ? 194 GLN B CG  1 
ATOM   5644 C  CD  . GLN B  1 194 ? 38.68331 0.39771   -61.94627 1.000 19.69611 ? 194 GLN B CD  1 
ATOM   5645 O  OE1 . GLN B  1 194 ? 39.72138 -0.17838  -62.27201 1.000 23.29277 ? 194 GLN B OE1 1 
ATOM   5646 N  NE2 . GLN B  1 194 ? 37.72905 0.70280   -62.81785 1.000 19.56553 ? 194 GLN B NE2 1 
ATOM   5647 N  N   . ASP B  1 195 ? 36.82609 -1.83917  -57.45308 1.000 25.24820 ? 195 ASP B N   1 
ATOM   5648 C  CA  . ASP B  1 195 ? 36.40874 -3.09862  -56.85437 1.000 25.99539 ? 195 ASP B CA  1 
ATOM   5649 C  C   . ASP B  1 195 ? 35.76549 -3.97567  -57.91820 1.000 25.05460 ? 195 ASP B C   1 
ATOM   5650 O  O   . ASP B  1 195 ? 35.08616 -3.47668  -58.82081 1.000 23.19465 ? 195 ASP B O   1 
ATOM   5651 C  CB  . ASP B  1 195 ? 35.43695 -2.88138  -55.68473 1.000 27.56295 ? 195 ASP B CB  1 
ATOM   5652 C  CG  . ASP B  1 195 ? 34.11038 -2.29753  -56.12362 1.000 24.66290 ? 195 ASP B CG  1 
ATOM   5653 O  OD1 . ASP B  1 195 ? 34.09842 -1.47941  -57.06574 1.000 25.02734 ? 195 ASP B OD1 1 
ATOM   5654 O  OD2 . ASP B  1 195 ? 33.07813 -2.65801  -55.52059 1.000 17.64257 ? 195 ASP B OD2 1 
ATOM   5655 N  N   . LYS B  1 196 ? 35.98803 -5.28400  -57.80752 1.000 29.24327 ? 196 LYS B N   1 
ATOM   5656 C  CA  . LYS B  1 196 ? 35.51411 -6.23717  -58.80012 1.000 21.00119 ? 196 LYS B CA  1 
ATOM   5657 C  C   . LYS B  1 196 ? 35.25474 -7.57836  -58.12817 1.000 23.31984 ? 196 LYS B C   1 
ATOM   5658 O  O   . LYS B  1 196 ? 35.66486 -7.82080  -56.99017 1.000 24.04890 ? 196 LYS B O   1 
ATOM   5659 C  CB  . LYS B  1 196 ? 36.52392 -6.40114  -59.94245 1.000 23.18375 ? 196 LYS B CB  1 
ATOM   5660 C  CG  . LYS B  1 196 ? 36.42982 -5.35769  -61.04332 1.000 27.93087 ? 196 LYS B CG  1 
ATOM   5661 C  CD  . LYS B  1 196 ? 37.77927 -5.16485  -61.72206 1.000 19.76261 ? 196 LYS B CD  1 
ATOM   5662 C  CE  . LYS B  1 196 ? 37.64598 -5.01555  -63.23654 1.000 20.60125 ? 196 LYS B CE  1 
ATOM   5663 N  NZ  . LYS B  1 196 ? 36.71024 -3.92833  -63.65152 1.000 14.44939 ? 196 LYS B NZ  1 
ATOM   5664 N  N   . SER B  1 197 ? 34.55714 -8.44957  -58.85342 1.000 23.24214 ? 197 SER B N   1 
ATOM   5665 C  CA  . SER B  1 197 ? 34.35451 -9.83504  -58.45884 1.000 21.06895 ? 197 SER B CA  1 
ATOM   5666 C  C   . SER B  1 197 ? 34.79038 -10.73708 -59.60358 1.000 22.86367 ? 197 SER B C   1 
ATOM   5667 O  O   . SER B  1 197 ? 34.67797 -10.37283 -60.77737 1.000 19.13980 ? 197 SER B O   1 
ATOM   5668 C  CB  . SER B  1 197 ? 32.89131 -10.11909 -58.09235 1.000 22.23807 ? 197 SER B CB  1 
ATOM   5669 O  OG  . SER B  1 197 ? 32.51466 -9.42136  -56.91865 1.000 21.63813 ? 197 SER B OG  1 
ATOM   5670 N  N   . PHE B  1 198 ? 35.28920 -11.91986 -59.25598 1.000 19.62113 ? 198 PHE B N   1 
ATOM   5671 C  CA  . PHE B  1 198 ? 35.87825 -12.81963 -60.23488 1.000 15.76238 ? 198 PHE B CA  1 
ATOM   5672 C  C   . PHE B  1 198 ? 35.25763 -14.20335 -60.13656 1.000 17.98471 ? 198 PHE B C   1 
ATOM   5673 O  O   . PHE B  1 198 ? 35.04280 -14.72306 -59.03752 1.000 16.54849 ? 198 PHE B O   1 
ATOM   5674 C  CB  . PHE B  1 198 ? 37.39624 -12.92638 -60.04423 1.000 18.01337 ? 198 PHE B CB  1 
ATOM   5675 C  CG  . PHE B  1 198 ? 38.12806 -11.63625 -60.27199 1.000 22.79743 ? 198 PHE B CG  1 
ATOM   5676 C  CD1 . PHE B  1 198 ? 38.51720 -11.26265 -61.54838 1.000 23.38733 ? 198 PHE B CD1 1 
ATOM   5677 C  CD2 . PHE B  1 198 ? 38.43066 -10.79822 -59.21126 1.000 17.33537 ? 198 PHE B CD2 1 
ATOM   5678 C  CE1 . PHE B  1 198 ? 39.19180 -10.07681 -61.76279 1.000 19.57154 ? 198 PHE B CE1 1 
ATOM   5679 C  CE2 . PHE B  1 198 ? 39.10590 -9.61113  -59.41937 1.000 18.93592 ? 198 PHE B CE2 1 
ATOM   5680 C  CZ  . PHE B  1 198 ? 39.48681 -9.24998  -60.69638 1.000 18.64332 ? 198 PHE B CZ  1 
ATOM   5681 N  N   . HIS B  1 199 ? 34.96696 -14.79139 -61.29479 1.000 21.61034 ? 199 HIS B N   1 
ATOM   5682 C  CA  . HIS B  1 199 ? 34.67356 -16.21215 -61.35453 1.000 21.20801 ? 199 HIS B CA  1 
ATOM   5683 C  C   . HIS B  1 199 ? 35.95647 -17.01135 -61.14103 1.000 23.72956 ? 199 HIS B C   1 
ATOM   5684 O  O   . HIS B  1 199 ? 37.06948 -16.47860 -61.18838 1.000 26.34430 ? 199 HIS B O   1 
ATOM   5685 C  CB  . HIS B  1 199 ? 34.05317 -16.58704 -62.70138 1.000 25.01058 ? 199 HIS B CB  1 
ATOM   5686 C  CG  . HIS B  1 199 ? 32.66549 -16.06292 -62.90522 1.000 21.45783 ? 199 HIS B CG  1 
ATOM   5687 N  ND1 . HIS B  1 199 ? 32.37978 -15.03101 -63.77334 1.000 24.24555 ? 199 HIS B ND1 1 
ATOM   5688 C  CD2 . HIS B  1 199 ? 31.48189 -16.43835 -62.36520 1.000 18.10446 ? 199 HIS B CD2 1 
ATOM   5689 C  CE1 . HIS B  1 199 ? 31.08113 -14.78879 -63.75425 1.000 21.03422 ? 199 HIS B CE1 1 
ATOM   5690 N  NE2 . HIS B  1 199 ? 30.51333 -15.62909 -62.90791 1.000 18.34288 ? 199 HIS B NE2 1 
ATOM   5691 N  N   . GLU B  1 200 ? 35.79481 -18.31523 -60.90615 1.000 28.15401 ? 200 GLU B N   1 
ATOM   5692 C  CA  . GLU B  1 200 ? 36.95561 -19.19744 -60.89880 1.000 30.74774 ? 200 GLU B CA  1 
ATOM   5693 C  C   . GLU B  1 200 ? 37.65076 -19.21420 -62.25370 1.000 31.23332 ? 200 GLU B C   1 
ATOM   5694 O  O   . GLU B  1 200 ? 38.84577 -19.52129 -62.32508 1.000 27.11027 ? 200 GLU B O   1 
ATOM   5695 C  CB  . GLU B  1 200 ? 36.53969 -20.61030 -60.48863 1.000 33.26045 ? 200 GLU B CB  1 
ATOM   5696 C  CG  . GLU B  1 200 ? 36.09195 -20.72390 -59.03719 1.000 30.62300 ? 200 GLU B CG  1 
ATOM   5697 C  CD  . GLU B  1 200 ? 37.24231 -20.57987 -58.05805 1.000 40.59322 ? 200 GLU B CD  1 
ATOM   5698 O  OE1 . GLU B  1 200 ? 38.38387 -20.93328 -58.42310 1.000 43.14893 ? 200 GLU B OE1 1 
ATOM   5699 O  OE2 . GLU B  1 200 ? 37.00639 -20.11152 -56.92416 1.000 45.92164 ? 200 GLU B OE2 1 
ATOM   5700 N  N   . ASP B  1 201 ? 36.92185 -18.88117 -63.32417 1.000 38.49211 ? 201 ASP B N   1 
ATOM   5701 C  CA  . ASP B  1 201 ? 37.52581 -18.66928 -64.63587 1.000 30.00616 ? 201 ASP B CA  1 
ATOM   5702 C  C   . ASP B  1 201 ? 38.63938 -17.63487 -64.59537 1.000 26.49148 ? 201 ASP B C   1 
ATOM   5703 O  O   . ASP B  1 201 ? 39.55311 -17.67127 -65.42671 1.000 27.47185 ? 201 ASP B O   1 
ATOM   5704 C  CB  . ASP B  1 201 ? 36.46065 -18.19523 -65.62652 1.000 25.41736 ? 201 ASP B CB  1 
ATOM   5705 C  CG  . ASP B  1 201 ? 36.01280 -19.27852 -66.57375 1.000 43.82746 ? 201 ASP B CG  1 
ATOM   5706 O  OD1 . ASP B  1 201 ? 36.77054 -20.24775 -66.78388 1.000 47.27199 ? 201 ASP B OD1 1 
ATOM   5707 O  OD2 . ASP B  1 201 ? 34.89894 -19.14580 -67.12091 1.000 45.25579 ? 201 ASP B OD2 1 
ATOM   5708 N  N   . GLY B  1 202 ? 38.57235 -16.69886 -63.65325 1.000 22.69801 ? 202 GLY B N   1 
ATOM   5709 C  CA  . GLY B  1 202 ? 39.34003 -15.48044 -63.72840 1.000 21.86202 ? 202 GLY B CA  1 
ATOM   5710 C  C   . GLY B  1 202 ? 38.63256 -14.35867 -64.45363 1.000 23.79595 ? 202 GLY B C   1 
ATOM   5711 O  O   . GLY B  1 202 ? 39.07127 -13.20538 -64.36115 1.000 24.43279 ? 202 GLY B O   1 
ATOM   5712 N  N   . SER B  1 203 ? 37.55007 -14.66132 -65.16553 1.000 20.42190 ? 203 SER B N   1 
ATOM   5713 C  CA  . SER B  1 203 ? 36.77832 -13.64482 -65.85753 1.000 20.47225 ? 203 SER B CA  1 
ATOM   5714 C  C   . SER B  1 203 ? 35.99447 -12.79590 -64.86139 1.000 25.70251 ? 203 SER B C   1 
ATOM   5715 O  O   . SER B  1 203 ? 35.78149 -13.17560 -63.70600 1.000 25.30485 ? 203 SER B O   1 
ATOM   5716 C  CB  . SER B  1 203 ? 35.82116 -14.29032 -66.86050 1.000 24.59619 ? 203 SER B CB  1 
ATOM   5717 O  OG  . SER B  1 203 ? 34.93786 -15.19303 -66.21578 1.000 20.62882 ? 203 SER B OG  1 
ATOM   5718 N  N   . LEU B  1 204 ? 35.56131 -11.62919 -65.32903 1.000 22.17223 ? 204 LEU B N   1 
ATOM   5719 C  CA  . LEU B  1 204 ? 34.78478 -10.73023 -64.48966 1.000 17.79737 ? 204 LEU B CA  1 
ATOM   5720 C  C   . LEU B  1 204 ? 33.40903 -11.31562 -64.20713 1.000 22.76748 ? 204 LEU B C   1 
ATOM   5721 O  O   . LEU B  1 204 ? 32.77484 -11.90898 -65.08370 1.000 22.54056 ? 204 LEU B O   1 
ATOM   5722 C  CB  . LEU B  1 204 ? 34.63051 -9.36889  -65.16479 1.000 19.43548 ? 204 LEU B CB  1 
ATOM   5723 C  CG  . LEU B  1 204 ? 35.90470 -8.58846  -65.46965 1.000 18.25559 ? 204 LEU B CG  1 
ATOM   5724 C  CD1 . LEU B  1 204 ? 35.57283 -7.29367  -66.19546 1.000 15.85295 ? 204 LEU B CD1 1 
ATOM   5725 C  CD2 . LEU B  1 204 ? 36.65260 -8.31098  -64.17849 1.000 19.69687 ? 204 LEU B CD2 1 
ATOM   5726 N  N   . PHE B  1 205 ? 32.94723 -11.14378 -62.97482 1.000 23.23305 ? 205 PHE B N   1 
ATOM   5727 C  CA  . PHE B  1 205 ? 31.57387 -11.45408 -62.61377 1.000 21.26455 ? 205 PHE B CA  1 
ATOM   5728 C  C   . PHE B  1 205 ? 30.76658 -10.16653 -62.53343 1.000 22.73564 ? 205 PHE B C   1 
ATOM   5729 O  O   . PHE B  1 205 ? 31.22722 -9.16450  -61.97899 1.000 24.29318 ? 205 PHE B O   1 
ATOM   5730 C  CB  . PHE B  1 205 ? 31.49629 -12.19811 -61.28003 1.000 16.69264 ? 205 PHE B CB  1 
ATOM   5731 C  CG  . PHE B  1 205 ? 30.12139 -12.20280 -60.67675 1.000 19.79845 ? 205 PHE B CG  1 
ATOM   5732 C  CD1 . PHE B  1 205 ? 29.11375 -12.98037 -61.22340 1.000 22.38998 ? 205 PHE B CD1 1 
ATOM   5733 C  CD2 . PHE B  1 205 ? 29.83239 -11.42045 -59.57046 1.000 22.60780 ? 205 PHE B CD2 1 
ATOM   5734 C  CE1 . PHE B  1 205 ? 27.84465 -12.98149 -60.67549 1.000 23.59695 ? 205 PHE B CE1 1 
ATOM   5735 C  CE2 . PHE B  1 205 ? 28.56589 -11.41799 -59.01760 1.000 24.06850 ? 205 PHE B CE2 1 
ATOM   5736 C  CZ  . PHE B  1 205 ? 27.57079 -12.19990 -59.57098 1.000 27.69805 ? 205 PHE B CZ  1 
ATOM   5737 N  N   . TYR B  1 206 ? 29.56154 -10.19841 -63.10088 1.000 20.34993 ? 206 TYR B N   1 
ATOM   5738 C  CA  . TYR B  1 206 ? 28.64472 -9.08490  -63.03056 1.000 24.03610 ? 206 TYR B CA  1 
ATOM   5739 C  C   . TYR B  1 206 ? 27.25181 -9.69602  -63.08680 1.000 23.12973 ? 206 TYR B C   1 
ATOM   5740 O  O   . TYR B  1 206 ? 26.97704 -10.49248 -63.99865 1.000 23.76329 ? 206 TYR B O   1 
ATOM   5741 C  CB  . TYR B  1 206 ? 28.83310 -8.07518  -64.16306 1.000 21.06794 ? 206 TYR B CB  1 
ATOM   5742 C  CG  . TYR B  1 206 ? 28.08119 -6.78224  -63.94590 1.000 21.44936 ? 206 TYR B CG  1 
ATOM   5743 C  CD1 . TYR B  1 206 ? 28.61820 -5.76848  -63.16430 1.000 21.15168 ? 206 TYR B CD1 1 
ATOM   5744 C  CD2 . TYR B  1 206 ? 26.83247 -6.57831  -64.51523 1.000 21.75471 ? 206 TYR B CD2 1 
ATOM   5745 C  CE1 . TYR B  1 206 ? 27.93453 -4.58727  -62.95814 1.000 15.72101 ? 206 TYR B CE1 1 
ATOM   5746 C  CE2 . TYR B  1 206 ? 26.14040 -5.40053  -64.31378 1.000 22.07542 ? 206 TYR B CE2 1 
ATOM   5747 C  CZ  . TYR B  1 206 ? 26.69679 -4.40883  -63.53510 1.000 18.40553 ? 206 TYR B CZ  1 
ATOM   5748 O  OH  . TYR B  1 206 ? 26.01239 -3.23382  -63.33293 1.000 19.69032 ? 206 TYR B OH  1 
ATOM   5749 N  N   . PRO B  1 207 ? 26.36767 -9.35327  -62.15185 1.000 23.36662 ? 207 PRO B N   1 
ATOM   5750 C  CA  . PRO B  1 207 ? 25.09107 -10.06998 -62.05040 1.000 24.76823 ? 207 PRO B CA  1 
ATOM   5751 C  C   . PRO B  1 207 ? 24.20399 -9.82978  -63.26202 1.000 35.39051 ? 207 PRO B C   1 
ATOM   5752 O  O   . PRO B  1 207 ? 24.11241 -8.71466  -63.78193 1.000 33.61032 ? 207 PRO B O   1 
ATOM   5753 C  CB  . PRO B  1 207 ? 24.46393 -9.49445  -60.77582 1.000 20.03745 ? 207 PRO B CB  1 
ATOM   5754 C  CG  . PRO B  1 207 ? 25.06208 -8.13189  -60.65443 1.000 23.68113 ? 207 PRO B CG  1 
ATOM   5755 C  CD  . PRO B  1 207 ? 26.46837 -8.25578  -61.17476 1.000 22.96816 ? 207 PRO B CD  1 
ATOM   5756 N  N   . ARG B  1 208 ? 23.55279 -10.90285 -63.71520 1.000 28.22310 ? 208 ARG B N   1 
ATOM   5757 C  CA  . ARG B  1 208 ? 22.58230 -10.78399 -64.79549 1.000 24.69249 ? 208 ARG B CA  1 
ATOM   5758 C  C   . ARG B  1 208 ? 21.26203 -10.20740 -64.30664 1.000 32.09141 ? 208 ARG B C   1 
ATOM   5759 O  O   . ARG B  1 208 ? 20.58402 -9.49799  -65.05767 1.000 33.41585 ? 208 ARG B O   1 
ATOM   5760 C  CB  . ARG B  1 208 ? 22.34084 -12.14829 -65.44337 1.000 32.35665 ? 208 ARG B CB  1 
ATOM   5761 C  CG  . ARG B  1 208 ? 23.55483 -12.74244 -66.13330 1.000 35.90310 ? 208 ARG B CG  1 
ATOM   5762 C  CD  . ARG B  1 208 ? 23.23550 -14.11014 -66.71099 1.000 37.28086 ? 208 ARG B CD  1 
ATOM   5763 N  NE  . ARG B  1 208 ? 22.03752 -14.08474 -67.54183 1.000 34.37056 ? 208 ARG B NE  1 
ATOM   5764 C  CZ  . ARG B  1 208 ? 22.02997 -13.80791 -68.83860 1.000 38.97737 ? 208 ARG B CZ  1 
ATOM   5765 N  NH1 . ARG B  1 208 ? 23.14512 -13.52076 -69.49089 1.000 30.97100 ? 208 ARG B NH1 1 
ATOM   5766 N  NH2 . ARG B  1 208 ? 20.87447 -13.81940 -69.49770 1.000 36.27473 ? 208 ARG B NH2 1 
ATOM   5767 N  N   . GLN B  1 209 ? 20.88708 -10.49684 -63.06721 1.000 28.97541 ? 209 GLN B N   1 
ATOM   5768 C  CA  . GLN B  1 209 ? 19.61903 -10.05076 -62.50956 1.000 28.38330 ? 209 GLN B CA  1 
ATOM   5769 C  C   . GLN B  1 209 ? 19.82252 -9.77293  -61.03179 1.000 29.85993 ? 209 GLN B C   1 
ATOM   5770 O  O   . GLN B  1 209 ? 20.84569 -10.15828 -60.45196 1.000 30.80859 ? 209 GLN B O   1 
ATOM   5771 C  CB  . GLN B  1 209 ? 18.51893 -11.10116 -62.70707 1.000 28.20438 ? 209 GLN B CB  1 
ATOM   5772 C  CG  . GLN B  1 209 ? 18.04104 -11.27009 -64.13519 1.000 34.43407 ? 209 GLN B CG  1 
ATOM   5773 C  CD  . GLN B  1 209 ? 17.04086 -12.39870 -64.27274 1.000 37.33868 ? 209 GLN B CD  1 
ATOM   5774 O  OE1 . GLN B  1 209 ? 17.18476 -13.44924 -63.64709 1.000 41.77445 ? 209 GLN B OE1 1 
ATOM   5775 N  NE2 . GLN B  1 209 ? 16.01449 -12.18467 -65.08652 1.000 33.73260 ? 209 GLN B NE2 1 
ATOM   5776 N  N   . PRO B  1 210 ? 18.86530 -9.09071  -60.38768 1.000 27.51993 ? 210 PRO B N   1 
ATOM   5777 C  CA  . PRO B  1 210 ? 18.86572 -9.02672  -58.91864 1.000 31.41450 ? 210 PRO B CA  1 
ATOM   5778 C  C   . PRO B  1 210 ? 18.82855 -10.40262 -58.26455 1.000 33.54227 ? 210 PRO B C   1 
ATOM   5779 O  O   . PRO B  1 210 ? 18.71352 -11.42424 -58.94967 1.000 33.27705 ? 210 PRO B O   1 
ATOM   5780 C  CB  . PRO B  1 210 ? 17.59959 -8.22007  -58.60781 1.000 24.47044 ? 210 PRO B CB  1 
ATOM   5781 C  CG  . PRO B  1 210 ? 17.43501 -7.33641  -59.79503 1.000 21.49591 ? 210 PRO B CG  1 
ATOM   5782 C  CD  . PRO B  1 210 ? 17.91255 -8.13499  -60.98073 1.000 21.60725 ? 210 PRO B CD  1 
ATOM   5783 N  N   . ASP B  1 211 ? 18.90545 -10.42915 -56.93127 1.000 41.07245 ? 211 ASP B N   1 
ATOM   5784 C  CA  . ASP B  1 211 ? 19.12766 -11.67684 -56.20216 1.000 49.35957 ? 211 ASP B CA  1 
ATOM   5785 C  C   . ASP B  1 211 ? 18.02912 -12.70009 -56.47391 1.000 52.64561 ? 211 ASP B C   1 
ATOM   5786 O  O   . ASP B  1 211 ? 18.29581 -13.79854 -56.97542 1.000 54.25219 ? 211 ASP B O   1 
ATOM   5787 C  CB  . ASP B  1 211 ? 19.23658 -11.38695 -54.70488 1.000 41.50471 ? 211 ASP B CB  1 
ATOM   5788 C  CG  . ASP B  1 211 ? 20.61218 -10.89709 -54.30787 1.000 52.14253 ? 211 ASP B CG  1 
ATOM   5789 O  OD1 . ASP B  1 211 ? 21.58210 -11.67185 -54.45190 1.000 55.29392 ? 211 ASP B OD1 1 
ATOM   5790 O  OD2 . ASP B  1 211 ? 20.72650 -9.73413  -53.86601 1.000 60.15921 ? 211 ASP B OD2 1 
ATOM   5791 N  N   . ASN B  1 212 ? 16.78481 -12.36464 -56.12975 1.000 42.60714 ? 212 ASN B N   1 
ATOM   5792 C  CA  . ASN B  1 212 ? 15.65571 -13.28205 -56.26127 1.000 46.78799 ? 212 ASN B CA  1 
ATOM   5793 C  C   . ASN B  1 212 ? 14.73256 -12.77857 -57.36218 1.000 41.84818 ? 212 ASN B C   1 
ATOM   5794 O  O   . ASN B  1 212 ? 13.76767 -12.05038 -57.08711 1.000 49.51672 ? 212 ASN B O   1 
ATOM   5795 C  CB  . ASN B  1 212 ? 14.90174 -13.40794 -54.93512 1.000 44.76922 ? 212 ASN B CB  1 
ATOM   5796 C  CG  . ASN B  1 212 ? 15.82909 -13.39902 -53.73467 1.000 54.60881 ? 212 ASN B CG  1 
ATOM   5797 O  OD1 . ASN B  1 212 ? 15.69899 -12.55930 -52.84320 1.000 58.12033 ? 212 ASN B OD1 1 
ATOM   5798 N  ND2 . ASN B  1 212 ? 16.77524 -14.33158 -53.70812 1.000 50.81800 ? 212 ASN B ND2 1 
ATOM   5799 N  N   . PRO B  1 213 ? 14.97742 -13.13526 -58.62181 1.000 38.87804 ? 213 PRO B N   1 
ATOM   5800 C  CA  . PRO B  1 213 ? 14.16987 -12.57702 -59.71134 1.000 39.86163 ? 213 PRO B CA  1 
ATOM   5801 C  C   . PRO B  1 213 ? 12.90119 -13.36892 -59.98077 1.000 51.52399 ? 213 PRO B C   1 
ATOM   5802 O  O   . PRO B  1 213 ? 12.94257 -14.59150 -60.15255 1.000 56.23972 ? 213 PRO B O   1 
ATOM   5803 C  CB  . PRO B  1 213 ? 15.12758 -12.63407 -60.90540 1.000 42.92739 ? 213 PRO B CB  1 
ATOM   5804 C  CG  . PRO B  1 213 ? 15.96433 -13.84467 -60.63210 1.000 39.54640 ? 213 PRO B CG  1 
ATOM   5805 C  CD  . PRO B  1 213 ? 16.07169 -13.98329 -59.12697 1.000 39.22759 ? 213 PRO B CD  1 
ATOM   5806 N  N   . SER B  1 214 ? 11.76571 -12.67906 -60.01264 1.000 52.35673 ? 214 SER B N   1 
ATOM   5807 C  CA  . SER B  1 214 ? 10.53893 -13.30434 -60.46801 1.000 48.78749 ? 214 SER B CA  1 
ATOM   5808 C  C   . SER B  1 214 ? 10.64843 -13.61228 -61.96052 1.000 50.58733 ? 214 SER B C   1 
ATOM   5809 O  O   . SER B  1 214 ? 11.41274 -12.96269 -62.67894 1.000 60.31157 ? 214 SER B O   1 
ATOM   5810 C  CB  . SER B  1 214 ? 9.34390  -12.39077 -60.20744 1.000 63.52028 ? 214 SER B CB  1 
ATOM   5811 O  OG  . SER B  1 214 ? 9.47125  -11.16971 -60.91571 1.000 65.71196 ? 214 SER B OG  1 
ATOM   5812 N  N   . PRO B  1 215 ? 9.90570  -14.60725 -62.45319 1.000 60.39305 ? 215 PRO B N   1 
ATOM   5813 C  CA  . PRO B  1 215 ? 9.93200  -14.88278 -63.89944 1.000 57.03959 ? 215 PRO B CA  1 
ATOM   5814 C  C   . PRO B  1 215 ? 9.44833  -13.71585 -64.74033 1.000 56.51058 ? 215 PRO B C   1 
ATOM   5815 O  O   . PRO B  1 215 ? 9.71495  -13.68755 -65.94835 1.000 55.72591 ? 215 PRO B O   1 
ATOM   5816 C  CB  . PRO B  1 215 ? 9.01270  -16.10409 -64.04489 1.000 53.78378 ? 215 PRO B CB  1 
ATOM   5817 C  CG  . PRO B  1 215 ? 8.15473  -16.08739 -62.82085 1.000 58.14589 ? 215 PRO B CG  1 
ATOM   5818 C  CD  . PRO B  1 215 ? 9.02452  -15.53995 -61.73077 1.000 60.01393 ? 215 PRO B CD  1 
ATOM   5819 N  N   . ASP B  1 216 ? 8.75113  -12.75050 -64.14039 1.000 54.77572 ? 216 ASP B N   1 
ATOM   5820 C  CA  . ASP B  1 216 ? 8.32934  -11.54887 -64.84560 1.000 58.34559 ? 216 ASP B CA  1 
ATOM   5821 C  C   . ASP B  1 216 ? 9.46397  -10.55383 -65.04897 1.000 54.39442 ? 216 ASP B C   1 
ATOM   5822 O  O   . ASP B  1 216 ? 9.29504  -9.59479  -65.80902 1.000 58.27447 ? 216 ASP B O   1 
ATOM   5823 C  CB  . ASP B  1 216 ? 7.18602  -10.87225 -64.08530 1.000 65.08101 ? 216 ASP B CB  1 
ATOM   5824 C  CG  . ASP B  1 216 ? 6.08470  -11.84249 -63.70669 1.000 69.06558 ? 216 ASP B CG  1 
ATOM   5825 O  OD1 . ASP B  1 216 ? 6.24227  -13.05392 -63.96888 1.000 64.01787 ? 216 ASP B OD1 1 
ATOM   5826 O  OD2 . ASP B  1 216 ? 5.06220  -11.39445 -63.14597 1.000 64.32850 ? 216 ASP B OD2 1 
ATOM   5827 N  N   . LEU B  1 217 ? 10.60552 -10.75640 -64.39667 1.000 48.49960 ? 217 LEU B N   1 
ATOM   5828 C  CA  . LEU B  1 217 ? 11.73176 -9.84309  -64.52258 1.000 35.68326 ? 217 LEU B CA  1 
ATOM   5829 C  C   . LEU B  1 217 ? 12.48277 -10.10870 -65.82650 1.000 37.52374 ? 217 LEU B C   1 
ATOM   5830 O  O   . LEU B  1 217 ? 12.65270 -11.26661 -66.21935 1.000 40.13247 ? 217 LEU B O   1 
ATOM   5831 C  CB  . LEU B  1 217 ? 12.68182 -10.00234 -63.33754 1.000 39.14815 ? 217 LEU B CB  1 
ATOM   5832 C  CG  . LEU B  1 217 ? 13.63630 -8.84269  -63.05775 1.000 31.82086 ? 217 LEU B CG  1 
ATOM   5833 C  CD1 . LEU B  1 217 ? 12.85669 -7.63698  -62.57372 1.000 24.72330 ? 217 LEU B CD1 1 
ATOM   5834 C  CD2 . LEU B  1 217 ? 14.68712 -9.24553  -62.04421 1.000 33.95549 ? 217 LEU B CD2 1 
ATOM   5835 N  N   . PRO B  1 218 ? 12.93018 -9.06115  -66.51903 1.000 35.96396 ? 218 PRO B N   1 
ATOM   5836 C  CA  . PRO B  1 218 ? 13.73692 -9.26821  -67.72622 1.000 30.23781 ? 218 PRO B CA  1 
ATOM   5837 C  C   . PRO B  1 218 ? 15.03188 -10.00111 -67.40978 1.000 31.19013 ? 218 PRO B C   1 
ATOM   5838 O  O   . PRO B  1 218 ? 15.52940 -9.99142  -66.28159 1.000 29.48451 ? 218 PRO B O   1 
ATOM   5839 C  CB  . PRO B  1 218 ? 14.01166 -7.84309  -68.22294 1.000 23.12530 ? 218 PRO B CB  1 
ATOM   5840 C  CG  . PRO B  1 218 ? 12.91243 -7.02266  -67.64154 1.000 30.48551 ? 218 PRO B CG  1 
ATOM   5841 C  CD  . PRO B  1 218 ? 12.61171 -7.63929  -66.30531 1.000 33.30602 ? 218 PRO B CD  1 
ATOM   5842 N  N   . ASP B  1 219 ? 15.57658 -10.64893 -68.43198 1.000 30.76847 ? 219 ASP B N   1 
ATOM   5843 C  CA  . ASP B  1 219 ? 16.82387 -11.39959 -68.30874 1.000 26.99991 ? 219 ASP B CA  1 
ATOM   5844 C  C   . ASP B  1 219 ? 17.71771 -11.05317 -69.48985 1.000 33.33836 ? 219 ASP B C   1 
ATOM   5845 O  O   . ASP B  1 219 ? 17.38738 -11.41798 -70.63770 1.000 38.47742 ? 219 ASP B O   1 
ATOM   5846 C  CB  . ASP B  1 219 ? 16.55409 -12.90031 -68.24916 1.000 36.40977 ? 219 ASP B CB  1 
ATOM   5847 C  CG  . ASP B  1 219 ? 17.75760 -13.69250 -67.77601 1.000 44.24272 ? 219 ASP B CG  1 
ATOM   5848 O  OD1 . ASP B  1 219 ? 18.65640 -13.09969 -67.14120 1.000 41.23893 ? 219 ASP B OD1 1 
ATOM   5849 O  OD2 . ASP B  1 219 ? 17.80610 -14.91141 -68.04342 1.000 50.98317 ? 219 ASP B OD2 1 
ATOM   5850 N  N   . PRO B  1 220 ? 18.84432 -10.36013 -69.27396 1.000 33.97545 ? 220 PRO B N   1 
ATOM   5851 C  CA  . PRO B  1 220 ? 19.35844 -9.83932  -67.99653 1.000 32.35479 ? 220 PRO B CA  1 
ATOM   5852 C  C   . PRO B  1 220 ? 18.54001 -8.67331  -67.44906 1.000 32.41175 ? 220 PRO B C   1 
ATOM   5853 O  O   . PRO B  1 220 ? 17.65524 -8.14384  -68.11870 1.000 27.49054 ? 220 PRO B O   1 
ATOM   5854 C  CB  . PRO B  1 220 ? 20.78872 -9.39070  -68.35232 1.000 30.01905 ? 220 PRO B CB  1 
ATOM   5855 C  CG  . PRO B  1 220 ? 21.12895 -10.11138 -69.62719 1.000 30.08321 ? 220 PRO B CG  1 
ATOM   5856 C  CD  . PRO B  1 220 ? 19.82588 -10.19500 -70.35730 1.000 32.34686 ? 220 PRO B CD  1 
ATOM   5857 N  N   . SER B  1 221 ? 18.82655 -8.25828  -66.21758 1.000 32.42273 ? 221 SER B N   1 
ATOM   5858 C  CA  . SER B  1 221 ? 18.15516 -7.12827  -65.59509 1.000 30.04336 ? 221 SER B CA  1 
ATOM   5859 C  C   . SER B  1 221 ? 19.18011 -6.28117  -64.85945 1.000 28.31705 ? 221 SER B C   1 
ATOM   5860 O  O   . SER B  1 221 ? 20.07790 -6.81327  -64.20063 1.000 25.37795 ? 221 SER B O   1 
ATOM   5861 C  CB  . SER B  1 221 ? 17.06250 -7.58380  -64.62139 1.000 28.41855 ? 221 SER B CB  1 
ATOM   5862 O  OG  . SER B  1 221 ? 16.56295 -6.48550  -63.87990 1.000 24.49287 ? 221 SER B OG  1 
ATOM   5863 N  N   . ILE B  1 222 ? 19.04219 -4.96008  -64.97731 1.000 27.07684 ? 222 ILE B N   1 
ATOM   5864 C  CA  . ILE B  1 222 ? 19.94610 -4.05721  -64.27962 1.000 22.52201 ? 222 ILE B CA  1 
ATOM   5865 C  C   . ILE B  1 222 ? 19.68077 -4.12897  -62.77958 1.000 20.64026 ? 222 ILE B C   1 
ATOM   5866 O  O   . ILE B  1 222 ? 18.54297 -4.32808  -62.33075 1.000 20.79394 ? 222 ILE B O   1 
ATOM   5867 C  CB  . ILE B  1 222 ? 19.79675 -2.61906  -64.81264 1.000 20.15138 ? 222 ILE B CB  1 
ATOM   5868 C  CG1 . ILE B  1 222 ? 20.79706 -1.68132  -64.13065 1.000 20.94804 ? 222 ILE B CG1 1 
ATOM   5869 C  CG2 . ILE B  1 222 ? 18.37153 -2.11992  -64.62770 1.000 20.57014 ? 222 ILE B CG2 1 
ATOM   5870 C  CD1 . ILE B  1 222 ? 20.85329 -0.30007  -64.72983 1.000 16.47182 ? 222 ILE B CD1 1 
ATOM   5871 N  N   . VAL B  1 223 ? 20.74531 -3.99107  -61.99515 1.000 19.23543 ? 223 VAL B N   1 
ATOM   5872 C  CA  . VAL B  1 223 ? 20.64393 -3.98766  -60.53809 1.000 24.20277 ? 223 VAL B CA  1 
ATOM   5873 C  C   . VAL B  1 223 ? 20.80135 -2.55392  -60.04228 1.000 22.82595 ? 223 VAL B C   1 
ATOM   5874 O  O   . VAL B  1 223 ? 21.45827 -1.73682  -60.70502 1.000 20.17237 ? 223 VAL B O   1 
ATOM   5875 C  CB  . VAL B  1 223 ? 21.68713 -4.92229  -59.90344 1.000 22.80001 ? 223 VAL B CB  1 
ATOM   5876 C  CG1 . VAL B  1 223 ? 21.52014 -6.33954  -60.43341 1.000 20.54179 ? 223 VAL B CG1 1 
ATOM   5877 C  CG2 . VAL B  1 223 ? 23.09509 -4.41120  -60.16866 1.000 19.42697 ? 223 VAL B CG2 1 
ATOM   5878 N  N   . PRO B  1 224 ? 20.20425 -2.19399  -58.90266 1.000 22.60275 ? 224 PRO B N   1 
ATOM   5879 C  CA  . PRO B  1 224 ? 20.37033 -0.82366  -58.39394 1.000 22.47228 ? 224 PRO B CA  1 
ATOM   5880 C  C   . PRO B  1 224 ? 21.76091 -0.54087  -57.86883 1.000 20.05065 ? 224 PRO B C   1 
ATOM   5881 O  O   . PRO B  1 224 ? 22.13043 0.63309   -57.75194 1.000 23.43441 ? 224 PRO B O   1 
ATOM   5882 C  CB  . PRO B  1 224 ? 19.32832 -0.73073  -57.26930 1.000 24.08786 ? 224 PRO B CB  1 
ATOM   5883 C  CG  . PRO B  1 224 ? 18.41724 -1.90601  -57.47267 1.000 22.92723 ? 224 PRO B CG  1 
ATOM   5884 C  CD  . PRO B  1 224 ? 19.25822 -2.97074  -58.08878 1.000 21.56743 ? 224 PRO B CD  1 
ATOM   5885 N  N   . ALA B  1 225 ? 22.53887 -1.56950  -57.54282 1.000 19.94462 ? 225 ALA B N   1 
ATOM   5886 C  CA  . ALA B  1 225 ? 23.88507 -1.36924  -57.03181 1.000 20.44036 ? 225 ALA B CA  1 
ATOM   5887 C  C   . ALA B  1 225 ? 24.68010 -2.65618  -57.17735 1.000 19.61191 ? 225 ALA B C   1 
ATOM   5888 O  O   . ALA B  1 225 ? 24.14809 -3.74936  -56.96330 1.000 26.42431 ? 225 ALA B O   1 
ATOM   5889 C  CB  . ALA B  1 225 ? 23.86326 -0.93461  -55.56443 1.000 18.71187 ? 225 ALA B CB  1 
ATOM   5890 N  N   . PHE B  1 226 ? 25.95588 -2.50946  -57.53199 1.000 19.16948 ? 226 PHE B N   1 
ATOM   5891 C  CA  . PHE B  1 226 ? 26.91472 -3.60489  -57.53971 1.000 21.67666 ? 226 PHE B CA  1 
ATOM   5892 C  C   . PHE B  1 226 ? 28.20571 -3.13984  -56.89283 1.000 24.95381 ? 226 PHE B C   1 
ATOM   5893 O  O   . PHE B  1 226 ? 28.68720 -2.03714  -57.17808 1.000 29.77570 ? 226 PHE B O   1 
ATOM   5894 C  CB  . PHE B  1 226 ? 27.20151 -4.10253  -58.96037 1.000 23.42523 ? 226 PHE B CB  1 
ATOM   5895 C  CG  . PHE B  1 226 ? 28.44230 -4.94407  -59.07054 1.000 24.31072 ? 226 PHE B CG  1 
ATOM   5896 C  CD1 . PHE B  1 226 ? 28.38655 -6.30931  -58.85919 1.000 19.73178 ? 226 PHE B CD1 1 
ATOM   5897 C  CD2 . PHE B  1 226 ? 29.66538 -4.36775  -59.38316 1.000 22.25027 ? 226 PHE B CD2 1 
ATOM   5898 C  CE1 . PHE B  1 226 ? 29.52643 -7.09025  -58.96125 1.000 27.26397 ? 226 PHE B CE1 1 
ATOM   5899 C  CE2 . PHE B  1 226 ? 30.81003 -5.14133  -59.47991 1.000 24.11878 ? 226 PHE B CE2 1 
ATOM   5900 C  CZ  . PHE B  1 226 ? 30.74054 -6.50557  -59.27312 1.000 24.19377 ? 226 PHE B CZ  1 
ATOM   5901 N  N   . CYS B  1 227 ? 28.75835 -3.98715  -56.02960 1.000 16.48597 ? 227 CYS B N   1 
ATOM   5902 C  CA  . CYS B  1 227 ? 30.09438 -3.79471  -55.49437 1.000 31.51057 ? 227 CYS B CA  1 
ATOM   5903 C  C   . CYS B  1 227 ? 30.77098 -5.15104  -55.41616 1.000 19.53399 ? 227 CYS B C   1 
ATOM   5904 O  O   . CYS B  1 227 ? 30.16745 -6.13196  -54.97351 1.000 21.71621 ? 227 CYS B O   1 
ATOM   5905 C  CB  . CYS B  1 227 ? 30.07113 -3.11421  -54.11891 1.000 43.12692 ? 227 CYS B CB  1 
ATOM   5906 S  SG  . CYS B  1 227 ? 29.53804 -4.16038  -52.76313 1.000 58.16358 ? 227 CYS B SG  1 
ATOM   5907 N  N   . GLY B  1 228 ? 32.01378 -5.20584  -55.87965 1.000 21.85337 ? 228 GLY B N   1 
ATOM   5908 C  CA  . GLY B  1 228 ? 32.73958 -6.45188  -55.87708 1.000 25.72789 ? 228 GLY B CA  1 
ATOM   5909 C  C   . GLY B  1 228 ? 33.38815 -6.73158  -54.54265 1.000 25.45685 ? 228 GLY B C   1 
ATOM   5910 O  O   . GLY B  1 228 ? 33.56080 -5.84635  -53.70509 1.000 30.14773 ? 228 GLY B O   1 
ATOM   5911 N  N   . ASP B  1 229 ? 33.75172 -7.99551  -54.34998 1.000 24.43421 ? 229 ASP B N   1 
ATOM   5912 C  CA  . ASP B  1 229 ? 34.37402 -8.43349  -53.11096 1.000 23.41090 ? 229 ASP B CA  1 
ATOM   5913 C  C   . ASP B  1 229 ? 35.88257 -8.22987  -53.09639 1.000 21.47567 ? 229 ASP B C   1 
ATOM   5914 O  O   . ASP B  1 229 ? 36.50937 -8.44855  -52.05536 1.000 24.29653 ? 229 ASP B O   1 
ATOM   5915 C  CB  . ASP B  1 229 ? 34.04678 -9.91107  -52.85423 1.000 20.10288 ? 229 ASP B CB  1 
ATOM   5916 C  CG  . ASP B  1 229 ? 34.29634 -10.79294 -54.07091 1.000 24.19638 ? 229 ASP B CG  1 
ATOM   5917 O  OD1 . ASP B  1 229 ? 35.12650 -10.42664 -54.93098 1.000 21.82113 ? 229 ASP B OD1 1 
ATOM   5918 O  OD2 . ASP B  1 229 ? 33.65176 -11.85898 -54.16727 1.000 29.86937 ? 229 ASP B OD2 1 
ATOM   5919 N  N   . THR B  1 230 ? 36.47561 -7.81398  -54.21236 1.000 21.14153 ? 230 THR B N   1 
ATOM   5920 C  CA  . THR B  1 230 ? 37.92114 -7.71277  -54.35179 1.000 24.09803 ? 230 THR B CA  1 
ATOM   5921 C  C   . THR B  1 230 ? 38.30555 -6.29307  -54.74480 1.000 19.41781 ? 230 THR B C   1 
ATOM   5922 O  O   . THR B  1 230 ? 37.67466 -5.69159  -55.61812 1.000 19.89178 ? 230 THR B O   1 
ATOM   5923 C  CB  . THR B  1 230 ? 38.43451 -8.70454  -55.40036 1.000 23.51521 ? 230 THR B CB  1 
ATOM   5924 O  OG1 . THR B  1 230 ? 37.99032 -10.02548 -55.06694 1.000 20.17194 ? 230 THR B OG1 1 
ATOM   5925 C  CG2 . THR B  1 230 ? 39.94260 -8.68748  -55.45270 1.000 18.99246 ? 230 THR B CG2 1 
ATOM   5926 N  N   . ILE B  1 231 ? 39.34344 -5.76256  -54.10026 1.000 14.57652 ? 231 ILE B N   1 
ATOM   5927 C  CA  . ILE B  1 231 ? 39.79783 -4.39367  -54.32036 1.000 16.62266 ? 231 ILE B CA  1 
ATOM   5928 C  C   . ILE B  1 231 ? 41.02863 -4.41722  -55.21530 1.000 19.99716 ? 231 ILE B C   1 
ATOM   5929 O  O   . ILE B  1 231 ? 41.97372 -5.17742  -54.96836 1.000 20.61351 ? 231 ILE B O   1 
ATOM   5930 C  CB  . ILE B  1 231 ? 40.10074 -3.68601  -52.98872 1.000 15.27316 ? 231 ILE B CB  1 
ATOM   5931 C  CG1 . ILE B  1 231 ? 38.83384 -3.59129  -52.13764 1.000 19.19191 ? 231 ILE B CG1 1 
ATOM   5932 C  CG2 . ILE B  1 231 ? 40.67890 -2.30095  -53.24075 1.000 16.12646 ? 231 ILE B CG2 1 
ATOM   5933 C  CD1 . ILE B  1 231 ? 37.71428 -2.81302  -52.79760 1.000 16.57406 ? 231 ILE B CD1 1 
ATOM   5934 N  N   . LEU B  1 232 ? 41.02085 -3.58115  -56.25069 1.000 21.08981 ? 232 LEU B N   1 
ATOM   5935 C  CA  . LEU B  1 232 ? 42.13031 -3.46264  -57.18279 1.000 17.97193 ? 232 LEU B CA  1 
ATOM   5936 C  C   . LEU B  1 232 ? 42.67141 -2.03985  -57.16644 1.000 19.77753 ? 232 LEU B C   1 
ATOM   5937 O  O   . LEU B  1 232 ? 41.93266 -1.07889  -56.92826 1.000 20.93546 ? 232 LEU B O   1 
ATOM   5938 C  CB  . LEU B  1 232 ? 41.71024 -3.83195  -58.61481 1.000 18.21239 ? 232 LEU B CB  1 
ATOM   5939 C  CG  . LEU B  1 232 ? 41.44768 -5.29830  -58.97226 1.000 21.13155 ? 232 LEU B CG  1 
ATOM   5940 C  CD1 . LEU B  1 232 ? 40.14905 -5.81019  -58.36351 1.000 20.74272 ? 232 LEU B CD1 1 
ATOM   5941 C  CD2 . LEU B  1 232 ? 41.43909 -5.47984  -60.48527 1.000 14.84178 ? 232 LEU B CD2 1 
ATOM   5942 N  N   . VAL B  1 233 ? 43.97339 -1.91493  -57.41536 1.000 17.41071 ? 233 VAL B N   1 
ATOM   5943 C  CA  . VAL B  1 233 ? 44.63489 -0.62347  -57.57195 1.000 17.72352 ? 233 VAL B CA  1 
ATOM   5944 C  C   . VAL B  1 233 ? 45.49037 -0.69647  -58.82792 1.000 17.49041 ? 233 VAL B C   1 
ATOM   5945 O  O   . VAL B  1 233 ? 46.37468 -1.55549  -58.92794 1.000 15.80415 ? 233 VAL B O   1 
ATOM   5946 C  CB  . VAL B  1 233 ? 45.49710 -0.25100  -56.35339 1.000 13.51897 ? 233 VAL B CB  1 
ATOM   5947 C  CG1 . VAL B  1 233 ? 46.06642 1.14991   -56.51742 1.000 12.83306 ? 233 VAL B CG1 1 
ATOM   5948 C  CG2 . VAL B  1 233 ? 44.69037 -0.35176  -55.07283 1.000 13.06597 ? 233 VAL B CG2 1 
ATOM   5949 N  N   . ASN B  1 234 ? 45.22569 0.19868   -59.78241 1.000 18.27368 ? 234 ASN B N   1 
ATOM   5950 C  CA  . ASN B  1 234 ? 45.93128 0.22292   -61.06559 1.000 15.25393 ? 234 ASN B CA  1 
ATOM   5951 C  C   . ASN B  1 234 ? 45.83510 -1.12427  -61.77889 1.000 20.67233 ? 234 ASN B C   1 
ATOM   5952 O  O   . ASN B  1 234 ? 46.78062 -1.57203  -62.43093 1.000 25.34776 ? 234 ASN B O   1 
ATOM   5953 C  CB  . ASN B  1 234 ? 47.39295 0.64099   -60.89224 1.000 14.67209 ? 234 ASN B CB  1 
ATOM   5954 C  CG  . ASN B  1 234 ? 47.53772 2.06834   -60.40334 1.000 17.57433 ? 234 ASN B CG  1 
ATOM   5955 O  OD1 . ASN B  1 234 ? 46.60543 2.86606   -60.49770 1.000 18.67538 ? 234 ASN B OD1 1 
ATOM   5956 N  ND2 . ASN B  1 234 ? 48.71443 2.40013   -59.88409 1.000 12.70915 ? 234 ASN B ND2 1 
ATOM   5957 N  N   . GLY B  1 235 ? 44.68286 -1.77802  -61.64943 1.000 22.32678 ? 235 GLY B N   1 
ATOM   5958 C  CA  . GLY B  1 235 ? 44.44823 -3.03348  -62.33319 1.000 20.97229 ? 235 GLY B CA  1 
ATOM   5959 C  C   . GLY B  1 235 ? 45.07011 -4.25285  -61.69374 1.000 20.29007 ? 235 GLY B C   1 
ATOM   5960 O  O   . GLY B  1 235 ? 45.18415 -5.28963  -62.35369 1.000 22.57374 ? 235 GLY B O   1 
ATOM   5961 N  N   . LYS B  1 236 ? 45.47427 -4.17136  -60.42809 1.000 17.55511 ? 236 LYS B N   1 
ATOM   5962 C  CA  . LYS B  1 236 ? 46.08493 -5.29861  -59.73642 1.000 17.46705 ? 236 LYS B CA  1 
ATOM   5963 C  C   . LYS B  1 236 ? 45.35901 -5.54561  -58.42299 1.000 16.15735 ? 236 LYS B C   1 
ATOM   5964 O  O   . LYS B  1 236 ? 45.14860 -4.61415  -57.64001 1.000 15.75741 ? 236 LYS B O   1 
ATOM   5965 C  CB  . LYS B  1 236 ? 47.57247 -5.05153  -59.47844 1.000 17.27462 ? 236 LYS B CB  1 
ATOM   5966 C  CG  . LYS B  1 236 ? 48.44773 -6.26331  -59.74182 1.000 18.35089 ? 236 LYS B CG  1 
ATOM   5967 C  CD  . LYS B  1 236 ? 48.35126 -6.69201  -61.19536 1.000 21.68721 ? 236 LYS B CD  1 
ATOM   5968 C  CE  . LYS B  1 236 ? 49.24609 -7.88024  -61.48906 1.000 23.17321 ? 236 LYS B CE  1 
ATOM   5969 N  NZ  . LYS B  1 236 ? 49.14935 -8.30614  -62.91290 1.000 21.37298 ? 236 LYS B NZ  1 
ATOM   5970 N  N   . VAL B  1 237 ? 44.98930 -6.80350  -58.18527 1.000 18.33886 ? 237 VAL B N   1 
ATOM   5971 C  CA  . VAL B  1 237 ? 44.27690 -7.17593  -56.96877 1.000 21.92305 ? 237 VAL B CA  1 
ATOM   5972 C  C   . VAL B  1 237 ? 45.19568 -7.02362  -55.76402 1.000 17.26138 ? 237 VAL B C   1 
ATOM   5973 O  O   . VAL B  1 237 ? 46.28712 -7.60693  -55.72305 1.000 15.33906 ? 237 VAL B O   1 
ATOM   5974 C  CB  . VAL B  1 237 ? 43.75094 -8.61390  -57.08171 1.000 21.97237 ? 237 VAL B CB  1 
ATOM   5975 C  CG1 . VAL B  1 237 ? 43.40020 -9.15468  -55.71186 1.000 21.46484 ? 237 VAL B CG1 1 
ATOM   5976 C  CG2 . VAL B  1 237 ? 42.54792 -8.67060  -58.01175 1.000 19.84058 ? 237 VAL B CG2 1 
ATOM   5977 N  N   . TRP B  1 238 ? 44.74052 -6.24636  -54.76530 1.000 16.66362 ? 238 TRP B N   1 
ATOM   5978 C  CA  . TRP B  1 238 ? 45.42270 -5.96161  -53.50136 1.000 19.83689 ? 238 TRP B CA  1 
ATOM   5979 C  C   . TRP B  1 238 ? 46.93746 -5.92328  -53.66337 1.000 17.88076 ? 238 TRP B C   1 
ATOM   5980 O  O   . TRP B  1 238 ? 47.64240 -6.75605  -53.07949 1.000 16.30914 ? 238 TRP B O   1 
ATOM   5981 C  CB  . TRP B  1 238 ? 45.04877 -6.99727  -52.43654 1.000 17.96428 ? 238 TRP B CB  1 
ATOM   5982 C  CG  . TRP B  1 238 ? 43.62740 -6.90820  -51.96685 1.000 21.64923 ? 238 TRP B CG  1 
ATOM   5983 C  CD1 . TRP B  1 238 ? 43.00512 -5.81311  -51.44123 1.000 19.98571 ? 238 TRP B CD1 1 
ATOM   5984 C  CD2 . TRP B  1 238 ? 42.65655 -7.96342  -51.95883 1.000 24.07947 ? 238 TRP B CD2 1 
ATOM   5985 N  NE1 . TRP B  1 238 ? 41.70419 -6.11697  -51.11861 1.000 22.30016 ? 238 TRP B NE1 1 
ATOM   5986 C  CE2 . TRP B  1 238 ? 41.46581 -7.43121  -51.42464 1.000 23.26953 ? 238 TRP B CE2 1 
ATOM   5987 C  CE3 . TRP B  1 238 ? 42.67799 -9.30487  -52.35361 1.000 20.74633 ? 238 TRP B CE3 1 
ATOM   5988 C  CZ2 . TRP B  1 238 ? 40.30733 -8.19305  -51.27730 1.000 22.42534 ? 238 TRP B CZ2 1 
ATOM   5989 C  CZ3 . TRP B  1 238 ? 41.52657 -10.05863 -52.20919 1.000 21.78775 ? 238 TRP B CZ3 1 
ATOM   5990 C  CH2 . TRP B  1 238 ? 40.35787 -9.50097  -51.67480 1.000 21.63826 ? 238 TRP B CH2 1 
ATOM   5991 N  N   . PRO B  1 239 ? 47.47445 -4.98494  -54.43001 1.000 16.52834 ? 239 PRO B N   1 
ATOM   5992 C  CA  . PRO B  1 239 ? 48.90018 -5.01037  -54.76051 1.000 16.15883 ? 239 PRO B CA  1 
ATOM   5993 C  C   . PRO B  1 239 ? 49.74276 -4.49438  -53.59910 1.000 19.68193 ? 239 PRO B C   1 
ATOM   5994 O  O   . PRO B  1 239 ? 49.23799 -4.12554  -52.54055 1.000 25.56600 ? 239 PRO B O   1 
ATOM   5995 C  CB  . PRO B  1 239 ? 48.98359 -4.08096  -55.97007 1.000 16.58754 ? 239 PRO B CB  1 
ATOM   5996 C  CG  . PRO B  1 239 ? 47.91739 -3.06827  -55.70496 1.000 16.68668 ? 239 PRO B CG  1 
ATOM   5997 C  CD  . PRO B  1 239 ? 46.80362 -3.79637  -54.98766 1.000 13.73632 ? 239 PRO B CD  1 
ATOM   5998 N  N   . TYR B  1 240 ? 51.05503 -4.48347  -53.81800 1.000 20.81350 ? 240 TYR B N   1 
ATOM   5999 C  CA  . TYR B  1 240 ? 51.99152 -3.88039  -52.88418 1.000 21.15554 ? 240 TYR B CA  1 
ATOM   6000 C  C   . TYR B  1 240 ? 52.99110 -3.04596  -53.67014 1.000 23.46979 ? 240 TYR B C   1 
ATOM   6001 O  O   . TYR B  1 240 ? 53.12947 -3.18916  -54.88741 1.000 24.07502 ? 240 TYR B O   1 
ATOM   6002 C  CB  . TYR B  1 240 ? 52.72069 -4.93231  -52.03381 1.000 21.49982 ? 240 TYR B CB  1 
ATOM   6003 C  CG  . TYR B  1 240 ? 53.77708 -5.71070  -52.78418 1.000 26.31242 ? 240 TYR B CG  1 
ATOM   6004 C  CD1 . TYR B  1 240 ? 53.45056 -6.86553  -53.48263 1.000 26.78281 ? 240 TYR B CD1 1 
ATOM   6005 C  CD2 . TYR B  1 240 ? 55.10388 -5.29442  -52.78871 1.000 21.43748 ? 240 TYR B CD2 1 
ATOM   6006 C  CE1 . TYR B  1 240 ? 54.41290 -7.57974  -54.17058 1.000 23.07307 ? 240 TYR B CE1 1 
ATOM   6007 C  CE2 . TYR B  1 240 ? 56.07110 -6.00013  -53.47407 1.000 22.99081 ? 240 TYR B CE2 1 
ATOM   6008 C  CZ  . TYR B  1 240 ? 55.72154 -7.14266  -54.16175 1.000 26.42290 ? 240 TYR B CZ  1 
ATOM   6009 O  OH  . TYR B  1 240 ? 56.68535 -7.84924  -54.84477 1.000 36.01858 ? 240 TYR B OH  1 
ATOM   6010 N  N   . ASP B  1 241 ? 53.69348 -2.16976  -52.95689 1.000 22.75861 ? 241 ASP B N   1 
ATOM   6011 C  CA  . ASP B  1 241 ? 54.68675 -1.30550  -53.57877 1.000 17.31234 ? 241 ASP B CA  1 
ATOM   6012 C  C   . ASP B  1 241 ? 55.78997 -1.02687  -52.57057 1.000 22.82707 ? 241 ASP B C   1 
ATOM   6013 O  O   . ASP B  1 241 ? 55.50747 -0.71727  -51.40926 1.000 24.61094 ? 241 ASP B O   1 
ATOM   6014 C  CB  . ASP B  1 241 ? 54.05379 0.00417   -54.06223 1.000 19.71568 ? 241 ASP B CB  1 
ATOM   6015 C  CG  . ASP B  1 241 ? 54.93771 0.75442   -55.03860 1.000 19.68476 ? 241 ASP B CG  1 
ATOM   6016 O  OD1 . ASP B  1 241 ? 55.99952 0.21766   -55.41593 1.000 25.77861 ? 241 ASP B OD1 1 
ATOM   6017 O  OD2 . ASP B  1 241 ? 54.56940 1.88119   -55.43100 1.000 20.08305 ? 241 ASP B OD2 1 
ATOM   6018 N  N   . GLU B  1 242 ? 57.03869 -1.14509  -53.01417 1.000 25.33106 ? 242 GLU B N   1 
ATOM   6019 C  CA  . GLU B  1 242 ? 58.20253 -0.90271  -52.16919 1.000 22.73651 ? 242 GLU B CA  1 
ATOM   6020 C  C   . GLU B  1 242 ? 58.66245 0.53394   -52.38624 1.000 20.48182 ? 242 GLU B C   1 
ATOM   6021 O  O   . GLU B  1 242 ? 59.09579 0.89483   -53.48488 1.000 25.44474 ? 242 GLU B O   1 
ATOM   6022 C  CB  . GLU B  1 242 ? 59.31621 -1.90076  -52.47907 1.000 26.78973 ? 242 GLU B CB  1 
ATOM   6023 C  CG  . GLU B  1 242 ? 59.00112 -3.32239  -52.03235 1.000 30.14114 ? 242 GLU B CG  1 
ATOM   6024 C  CD  . GLU B  1 242 ? 60.06474 -4.32030  -52.44606 1.000 40.88662 ? 242 GLU B CD  1 
ATOM   6025 O  OE1 . GLU B  1 242 ? 60.80422 -4.03939  -53.41297 1.000 38.59974 ? 242 GLU B OE1 1 
ATOM   6026 O  OE2 . GLU B  1 242 ? 60.16184 -5.38654  -51.80188 1.000 42.35760 ? 242 GLU B OE2 1 
ATOM   6027 N  N   . LEU B  1 243 ? 58.56609 1.34912   -51.34019 1.000 24.86678 ? 243 LEU B N   1 
ATOM   6028 C  CA  . LEU B  1 243 ? 58.86379 2.77026   -51.41515 1.000 22.30822 ? 243 LEU B CA  1 
ATOM   6029 C  C   . LEU B  1 243 ? 60.08899 3.11516   -50.57924 1.000 25.76159 ? 243 LEU B C   1 
ATOM   6030 O  O   . LEU B  1 243 ? 60.53597 2.33832   -49.73071 1.000 27.29194 ? 243 LEU B O   1 
ATOM   6031 C  CB  . LEU B  1 243 ? 57.67223 3.60662   -50.93767 1.000 23.48856 ? 243 LEU B CB  1 
ATOM   6032 C  CG  . LEU B  1 243 ? 56.33751 3.40433   -51.65145 1.000 22.16988 ? 243 LEU B CG  1 
ATOM   6033 C  CD1 . LEU B  1 243 ? 55.32652 4.43086   -51.16369 1.000 23.29107 ? 243 LEU B CD1 1 
ATOM   6034 C  CD2 . LEU B  1 243 ? 56.51802 3.49022   -53.15733 1.000 20.72112 ? 243 LEU B CD2 1 
ATOM   6035 N  N   . GLU B  1 244 ? 60.62668 4.31442   -50.83421 1.000 25.70578 ? 244 GLU B N   1 
ATOM   6036 C  CA  . GLU B  1 244 ? 61.72005 4.95328   -50.12136 1.000 24.82716 ? 244 GLU B CA  1 
ATOM   6037 C  C   . GLU B  1 244 ? 61.17616 5.78485   -48.96344 1.000 29.05877 ? 244 GLU B C   1 
ATOM   6038 O  O   . GLU B  1 244 ? 60.04625 6.28142   -49.02490 1.000 27.66861 ? 244 GLU B O   1 
ATOM   6039 C  CB  . GLU B  1 244 ? 62.51938 5.84971   -51.06436 1.000 21.93373 ? 244 GLU B CB  1 
ATOM   6040 C  CG  . GLU B  1 244 ? 63.03727 5.14708   -52.30771 1.000 21.15788 ? 244 GLU B CG  1 
ATOM   6041 C  CD  . GLU B  1 244 ? 63.73514 6.09790   -53.26214 1.000 32.94508 ? 244 GLU B CD  1 
ATOM   6042 O  OE1 . GLU B  1 244 ? 64.17168 7.17970   -52.81286 1.000 26.55320 ? 244 GLU B OE1 1 
ATOM   6043 O  OE2 . GLU B  1 244 ? 63.84178 5.76686   -54.46301 1.000 33.14691 ? 244 GLU B OE2 1 
ATOM   6044 N  N   . PRO B  1 245 ? 61.94982 5.95050   -47.88723 1.000 29.32890 ? 245 PRO B N   1 
ATOM   6045 C  CA  . PRO B  1 245 ? 61.46734 6.74238   -46.73302 1.000 25.29643 ? 245 PRO B CA  1 
ATOM   6046 C  C   . PRO B  1 245 ? 61.53751 8.24935   -46.97330 1.000 25.64129 ? 245 PRO B C   1 
ATOM   6047 O  O   . PRO B  1 245 ? 62.41874 8.96516   -46.49803 1.000 29.16596 ? 245 PRO B O   1 
ATOM   6048 C  CB  . PRO B  1 245 ? 62.40370 6.29545   -45.60864 1.000 24.52995 ? 245 PRO B CB  1 
ATOM   6049 C  CG  . PRO B  1 245 ? 63.67464 5.95410   -46.31021 1.000 29.58167 ? 245 PRO B CG  1 
ATOM   6050 C  CD  . PRO B  1 245 ? 63.27595 5.35876   -47.63582 1.000 24.12020 ? 245 PRO B CD  1 
ATOM   6051 N  N   . ARG B  1 246 ? 60.57324 8.75371   -47.73386 1.000 25.33540 ? 246 ARG B N   1 
ATOM   6052 C  CA  . ARG B  1 246 ? 60.52039 10.17253  -48.07014 1.000 24.96789 ? 246 ARG B CA  1 
ATOM   6053 C  C   . ARG B  1 246 ? 59.06645 10.54971  -48.33801 1.000 25.93544 ? 246 ARG B C   1 
ATOM   6054 O  O   . ARG B  1 246 ? 58.14415 9.80211   -47.99629 1.000 23.94798 ? 246 ARG B O   1 
ATOM   6055 C  CB  . ARG B  1 246 ? 61.44069 10.47569  -49.26418 1.000 19.62471 ? 246 ARG B CB  1 
ATOM   6056 C  CG  . ARG B  1 246 ? 61.20802 9.57990   -50.46632 1.000 20.44593 ? 246 ARG B CG  1 
ATOM   6057 C  CD  . ARG B  1 246 ? 61.71530 10.23645  -51.73314 1.000 22.49880 ? 246 ARG B CD  1 
ATOM   6058 N  NE  . ARG B  1 246 ? 60.89299 11.38046  -52.10709 1.000 29.20428 ? 246 ARG B NE  1 
ATOM   6059 C  CZ  . ARG B  1 246 ? 61.20981 12.25466  -53.05222 1.000 32.86755 ? 246 ARG B CZ  1 
ATOM   6060 N  NH1 . ARG B  1 246 ? 62.34222 12.15909  -53.73027 1.000 27.86099 ? 246 ARG B NH1 1 
ATOM   6061 N  NH2 . ARG B  1 246 ? 60.37197 13.25322  -53.31963 1.000 25.54638 ? 246 ARG B NH2 1 
ATOM   6062 N  N   . LYS B  1 247 ? 58.86078 11.71147  -48.95414 1.000 25.81297 ? 247 LYS B N   1 
ATOM   6063 C  CA  . LYS B  1 247 ? 57.52504 12.19735  -49.27025 1.000 25.88033 ? 247 LYS B CA  1 
ATOM   6064 C  C   . LYS B  1 247 ? 57.11407 11.73072  -50.66050 1.000 24.63538 ? 247 LYS B C   1 
ATOM   6065 O  O   . LYS B  1 247 ? 57.88519 11.85182  -51.61805 1.000 23.65604 ? 247 LYS B O   1 
ATOM   6066 C  CB  . LYS B  1 247 ? 57.46662 13.72394  -49.19079 1.000 20.80196 ? 247 LYS B CB  1 
ATOM   6067 C  CG  . LYS B  1 247 ? 57.61170 14.28396  -47.78588 1.000 19.78652 ? 247 LYS B CG  1 
ATOM   6068 C  CD  . LYS B  1 247 ? 57.33234 15.77803  -47.75935 1.000 22.32427 ? 247 LYS B CD  1 
ATOM   6069 C  CE  . LYS B  1 247 ? 58.31052 16.54391  -48.63736 1.000 33.31891 ? 247 LYS B CE  1 
ATOM   6070 N  NZ  . LYS B  1 247 ? 59.71525 16.40163  -48.16267 1.000 30.74064 ? 247 LYS B NZ  1 
ATOM   6071 N  N   . TYR B  1 248 ? 55.89956 11.19912  -50.76277 1.000 18.32365 ? 248 TYR B N   1 
ATOM   6072 C  CA  . TYR B  1 248 ? 55.31681 10.77881  -52.02554 1.000 17.60745 ? 248 TYR B CA  1 
ATOM   6073 C  C   . TYR B  1 248 ? 54.07243 11.60506  -52.31683 1.000 18.18193 ? 248 TYR B C   1 
ATOM   6074 O  O   . TYR B  1 248 ? 53.44318 12.16311  -51.41374 1.000 17.97224 ? 248 TYR B O   1 
ATOM   6075 C  CB  . TYR B  1 248 ? 54.95269 9.28736   -52.00954 1.000 20.25500 ? 248 TYR B CB  1 
ATOM   6076 C  CG  . TYR B  1 248 ? 56.12187 8.35984   -52.23679 1.000 21.24230 ? 248 TYR B CG  1 
ATOM   6077 C  CD1 . TYR B  1 248 ? 56.99409 8.04408   -51.20402 1.000 18.63916 ? 248 TYR B CD1 1 
ATOM   6078 C  CD2 . TYR B  1 248 ? 56.34931 7.79387   -53.48474 1.000 17.10555 ? 248 TYR B CD2 1 
ATOM   6079 C  CE1 . TYR B  1 248 ? 58.06355 7.19525   -51.40827 1.000 20.73011 ? 248 TYR B CE1 1 
ATOM   6080 C  CE2 . TYR B  1 248 ? 57.41498 6.94493   -53.69850 1.000 22.40762 ? 248 TYR B CE2 1 
ATOM   6081 C  CZ  . TYR B  1 248 ? 58.26902 6.64834   -52.65642 1.000 25.99075 ? 248 TYR B CZ  1 
ATOM   6082 O  OH  . TYR B  1 248 ? 59.33318 5.80225   -52.86424 1.000 28.67208 ? 248 TYR B OH  1 
ATOM   6083 N  N   . ARG B  1 249 ? 53.72295 11.67620  -53.59620 1.000 21.67125 ? 249 ARG B N   1 
ATOM   6084 C  CA  . ARG B  1 249 ? 52.50595 12.33662  -54.04812 1.000 19.21822 ? 249 ARG B CA  1 
ATOM   6085 C  C   . ARG B  1 249 ? 51.58787 11.28546  -54.65243 1.000 17.56649 ? 249 ARG B C   1 
ATOM   6086 O  O   . ARG B  1 249 ? 51.93900 10.65343  -55.65382 1.000 18.11867 ? 249 ARG B O   1 
ATOM   6087 C  CB  . ARG B  1 249 ? 52.81488 13.43096  -55.06890 1.000 17.89786 ? 249 ARG B CB  1 
ATOM   6088 C  CG  . ARG B  1 249 ? 51.59013 14.20191  -55.52838 1.000 16.93167 ? 249 ARG B CG  1 
ATOM   6089 C  CD  . ARG B  1 249 ? 51.94564 15.20643  -56.60745 1.000 16.89104 ? 249 ARG B CD  1 
ATOM   6090 N  NE  . ARG B  1 249 ? 50.80682 16.03715  -56.97874 1.000 12.88454 ? 249 ARG B NE  1 
ATOM   6091 C  CZ  . ARG B  1 249 ? 50.79934 16.87898  -58.00302 1.000 18.02013 ? 249 ARG B CZ  1 
ATOM   6092 N  NH1 . ARG B  1 249 ? 51.85193 17.01539  -58.79314 1.000 16.46141 ? 249 ARG B NH1 1 
ATOM   6093 N  NH2 . ARG B  1 249 ? 49.70733 17.59914  -58.24319 1.000 19.56524 ? 249 ARG B NH2 1 
ATOM   6094 N  N   . PHE B  1 250 ? 50.42371 11.09309  -54.04369 1.000 18.75496 ? 250 PHE B N   1 
ATOM   6095 C  CA  . PHE B  1 250 ? 49.44610 10.13176  -54.53158 1.000 18.71107 ? 250 PHE B CA  1 
ATOM   6096 C  C   . PHE B  1 250 ? 48.30098 10.86519  -55.21543 1.000 16.94916 ? 250 PHE B C   1 
ATOM   6097 O  O   . PHE B  1 250 ? 47.71612 11.78952  -54.64114 1.000 15.81171 ? 250 PHE B O   1 
ATOM   6098 C  CB  . PHE B  1 250 ? 48.91410 9.25946   -53.39425 1.000 17.44514 ? 250 PHE B CB  1 
ATOM   6099 C  CG  . PHE B  1 250 ? 49.95426 8.37120   -52.77397 1.000 17.92863 ? 250 PHE B CG  1 
ATOM   6100 C  CD1 . PHE B  1 250 ? 50.43063 7.26271   -53.45327 1.000 22.01894 ? 250 PHE B CD1 1 
ATOM   6101 C  CD2 . PHE B  1 250 ? 50.44953 8.63904   -51.50848 1.000 20.09609 ? 250 PHE B CD2 1 
ATOM   6102 C  CE1 . PHE B  1 250 ? 51.38686 6.44034   -52.88466 1.000 24.68610 ? 250 PHE B CE1 1 
ATOM   6103 C  CE2 . PHE B  1 250 ? 51.40540 7.82033   -50.93352 1.000 22.83331 ? 250 PHE B CE2 1 
ATOM   6104 C  CZ  . PHE B  1 250 ? 51.87397 6.71937   -51.62262 1.000 21.68137 ? 250 PHE B CZ  1 
ATOM   6105 N  N   . ARG B  1 251 ? 47.99717 10.45915  -56.44559 1.000 17.40219 ? 251 ARG B N   1 
ATOM   6106 C  CA  . ARG B  1 251 ? 46.85068 10.97327  -57.19224 1.000 14.30481 ? 251 ARG B CA  1 
ATOM   6107 C  C   . ARG B  1 251 ? 45.77903 9.88978   -57.13449 1.000 15.38832 ? 251 ARG B C   1 
ATOM   6108 O  O   . ARG B  1 251 ? 45.69824 9.02025   -58.00299 1.000 15.11637 ? 251 ARG B O   1 
ATOM   6109 C  CB  . ARG B  1 251 ? 47.23965 11.32148  -58.62496 1.000 17.43739 ? 251 ARG B CB  1 
ATOM   6110 C  CG  . ARG B  1 251 ? 48.56085 12.06689  -58.74828 1.000 14.08857 ? 251 ARG B CG  1 
ATOM   6111 C  CD  . ARG B  1 251 ? 48.52465 13.40523  -58.02960 1.000 12.15811 ? 251 ARG B CD  1 
ATOM   6112 N  NE  . ARG B  1 251 ? 47.62537 14.35311  -58.67707 1.000 19.27275 ? 251 ARG B NE  1 
ATOM   6113 C  CZ  . ARG B  1 251 ? 47.97687 15.16347  -59.66638 1.000 15.87144 ? 251 ARG B CZ  1 
ATOM   6114 N  NH1 . ARG B  1 251 ? 49.20496 15.16224  -60.15790 1.000 14.10270 ? 251 ARG B NH1 1 
ATOM   6115 N  NH2 . ARG B  1 251 ? 47.07295 15.99450  -60.17677 1.000 15.00259 ? 251 ARG B NH2 1 
ATOM   6116 N  N   . ILE B  1 252 ? 44.95692 9.94058   -56.09091 1.000 16.66046 ? 252 ILE B N   1 
ATOM   6117 C  CA  . ILE B  1 252 ? 43.99026 8.88235   -55.82220 1.000 12.04074 ? 252 ILE B CA  1 
ATOM   6118 C  C   . ILE B  1 252 ? 42.73330 9.11153   -56.64932 1.000 12.14333 ? 252 ILE B C   1 
ATOM   6119 O  O   . ILE B  1 252 ? 42.27617 10.24832  -56.81734 1.000 14.68218 ? 252 ILE B O   1 
ATOM   6120 C  CB  . ILE B  1 252 ? 43.66994 8.82153   -54.31857 1.000 12.81911 ? 252 ILE B CB  1 
ATOM   6121 C  CG1 . ILE B  1 252 ? 44.96439 8.79115   -53.50253 1.000 12.51292 ? 252 ILE B CG1 1 
ATOM   6122 C  CG2 . ILE B  1 252 ? 42.81948 7.60249   -54.00072 1.000 12.13724 ? 252 ILE B CG2 1 
ATOM   6123 C  CD1 . ILE B  1 252 ? 44.74567 8.64924   -52.01208 1.000 10.45524 ? 252 ILE B CD1 1 
ATOM   6124 N  N   . LEU B  1 253 ? 42.16953 8.02412   -57.17318 1.000 17.66245 ? 253 LEU B N   1 
ATOM   6125 C  CA  . LEU B  1 253 ? 40.93559 8.07480   -57.94588 1.000 13.80472 ? 253 LEU B CA  1 
ATOM   6126 C  C   . LEU B  1 253 ? 40.07577 6.87201   -57.59589 1.000 13.11971 ? 253 LEU B C   1 
ATOM   6127 O  O   . LEU B  1 253 ? 40.57708 5.74702   -57.53025 1.000 16.42967 ? 253 LEU B O   1 
ATOM   6128 C  CB  . LEU B  1 253 ? 41.21829 8.09430   -59.45400 1.000 10.07376 ? 253 LEU B CB  1 
ATOM   6129 C  CG  . LEU B  1 253 ? 40.01671 7.81325   -60.36442 1.000 11.57700 ? 253 LEU B CG  1 
ATOM   6130 C  CD1 . LEU B  1 253 ? 38.94260 8.88017   -60.21126 1.000 9.67704  ? 253 LEU B CD1 1 
ATOM   6131 C  CD2 . LEU B  1 253 ? 40.44646 7.68875   -61.81761 1.000 13.09670 ? 253 LEU B CD2 1 
ATOM   6132 N  N   . ASN B  1 254 ? 38.78577 7.11209   -57.37257 1.000 15.60431 ? 254 ASN B N   1 
ATOM   6133 C  CA  . ASN B  1 254 ? 37.80374 6.04888   -57.16893 1.000 13.44136 ? 254 ASN B CA  1 
ATOM   6134 C  C   . ASN B  1 254 ? 37.07932 5.83929   -58.49404 1.000 12.76304 ? 254 ASN B C   1 
ATOM   6135 O  O   . ASN B  1 254 ? 36.23313 6.64742   -58.88617 1.000 11.84261 ? 254 ASN B O   1 
ATOM   6136 C  CB  . ASN B  1 254 ? 36.83223 6.40717   -56.04910 1.000 14.60885 ? 254 ASN B CB  1 
ATOM   6137 C  CG  . ASN B  1 254 ? 35.85985 5.27973   -55.72779 1.000 15.84702 ? 254 ASN B CG  1 
ATOM   6138 O  OD1 . ASN B  1 254 ? 35.81017 4.26515   -56.42389 1.000 17.50842 ? 254 ASN B OD1 1 
ATOM   6139 N  ND2 . ASN B  1 254 ? 35.07226 5.46167   -54.67333 1.000 11.94107 ? 254 ASN B ND2 1 
ATOM   6140 N  N   . ALA B  1 255 ? 37.41671 4.75329   -59.18629 1.000 14.08916 ? 255 ALA B N   1 
ATOM   6141 C  CA  . ALA B  1 255 ? 36.79269 4.40375   -60.45648 1.000 15.93481 ? 255 ALA B CA  1 
ATOM   6142 C  C   . ALA B  1 255 ? 35.87806 3.19000   -60.31915 1.000 12.74904 ? 255 ALA B C   1 
ATOM   6143 O  O   . ALA B  1 255 ? 35.67120 2.44725   -61.28115 1.000 13.13756 ? 255 ALA B O   1 
ATOM   6144 C  CB  . ALA B  1 255 ? 37.85127 4.16038   -61.53131 1.000 12.21694 ? 255 ALA B CB  1 
ATOM   6145 N  N   . SER B  1 256 ? 35.32877 2.97837   -59.12548 1.000 13.45641 ? 256 SER B N   1 
ATOM   6146 C  CA  . SER B  1 256 ? 34.35610 1.91751   -58.91896 1.000 12.75204 ? 256 SER B CA  1 
ATOM   6147 C  C   . SER B  1 256 ? 33.01243 2.29651   -59.53547 1.000 14.04267 ? 256 SER B C   1 
ATOM   6148 O  O   . SER B  1 256 ? 32.74595 3.45959   -59.85215 1.000 13.33947 ? 256 SER B O   1 
ATOM   6149 C  CB  . SER B  1 256 ? 34.17638 1.63334   -57.42730 1.000 17.10197 ? 256 SER B CB  1 
ATOM   6150 O  OG  . SER B  1 256 ? 35.38595 1.18953   -56.83694 1.000 24.47848 ? 256 SER B OG  1 
ATOM   6151 N  N   . ASN B  1 257 ? 32.15395 1.28851   -59.70023 1.000 15.38281 ? 257 ASN B N   1 
ATOM   6152 C  CA  . ASN B  1 257 ? 30.81114 1.54855   -60.20746 1.000 14.80865 ? 257 ASN B CA  1 
ATOM   6153 C  C   . ASN B  1 257 ? 29.92771 2.18501   -59.14091 1.000 15.65002 ? 257 ASN B C   1 
ATOM   6154 O  O   . ASN B  1 257 ? 29.10171 3.05114   -59.45035 1.000 16.95047 ? 257 ASN B O   1 
ATOM   6155 C  CB  . ASN B  1 257 ? 30.17703 0.25402   -60.71878 1.000 17.43616 ? 257 ASN B CB  1 
ATOM   6156 C  CG  . ASN B  1 257 ? 30.71407 -0.16618  -62.07269 1.000 18.85047 ? 257 ASN B CG  1 
ATOM   6157 O  OD1 . ASN B  1 257 ? 31.82093 0.20923   -62.45848 1.000 20.54280 ? 257 ASN B OD1 1 
ATOM   6158 N  ND2 . ASN B  1 257 ? 29.92625 -0.94736  -62.80540 1.000 14.88947 ? 257 ASN B ND2 1 
ATOM   6159 N  N   . THR B  1 258 ? 30.09267 1.77940   -57.88071 1.000 14.42793 ? 258 THR B N   1 
ATOM   6160 C  CA  . THR B  1 258 ? 29.16550 2.17318   -56.82540 1.000 14.93140 ? 258 THR B CA  1 
ATOM   6161 C  C   . THR B  1 258 ? 29.87843 2.46034   -55.50884 1.000 15.91530 ? 258 THR B C   1 
ATOM   6162 O  O   . THR B  1 258 ? 29.51114 3.39082   -54.78352 1.000 15.25975 ? 258 THR B O   1 
ATOM   6163 C  CB  . THR B  1 258 ? 28.12047 1.07281   -56.61552 1.000 15.78124 ? 258 THR B CB  1 
ATOM   6164 O  OG1 . THR B  1 258 ? 27.35023 0.90405   -57.81279 1.000 21.12510 ? 258 THR B OG1 1 
ATOM   6165 C  CG2 . THR B  1 258 ? 27.19261 1.41116   -55.45546 1.000 22.25221 ? 258 THR B CG2 1 
ATOM   6166 N  N   . ARG B  1 259 ? 30.90707 1.67353   -55.20623 1.000 16.34582 ? 259 ARG B N   1 
ATOM   6167 C  CA  . ARG B  1 259 ? 31.48563 1.65456   -53.86932 1.000 13.67042 ? 259 ARG B CA  1 
ATOM   6168 C  C   . ARG B  1 259 ? 32.11859 2.99400   -53.50178 1.000 13.92621 ? 259 ARG B C   1 
ATOM   6169 O  O   . ARG B  1 259 ? 32.83660 3.60472   -54.29751 1.000 15.16956 ? 259 ARG B O   1 
ATOM   6170 C  CB  . ARG B  1 259 ? 32.52408 0.53633   -53.78047 1.000 13.58401 ? 259 ARG B CB  1 
ATOM   6171 C  CG  . ARG B  1 259 ? 33.27813 0.48492   -52.47188 1.000 17.88340 ? 259 ARG B CG  1 
ATOM   6172 C  CD  . ARG B  1 259 ? 34.35592 -0.58516  -52.50421 1.000 16.73763 ? 259 ARG B CD  1 
ATOM   6173 N  NE  . ARG B  1 259 ? 33.80320 -1.93257  -52.55467 1.000 16.88988 ? 259 ARG B NE  1 
ATOM   6174 C  CZ  . ARG B  1 259 ? 33.59405 -2.69426  -51.48987 1.000 17.72209 ? 259 ARG B CZ  1 
ATOM   6175 N  NH1 . ARG B  1 259 ? 33.87690 -2.26872  -50.26953 1.000 14.78419 ? 259 ARG B NH1 1 
ATOM   6176 N  NH2 . ARG B  1 259 ? 33.08934 -3.91367  -51.65358 1.000 22.74939 ? 259 ARG B NH2 1 
ATOM   6177 N  N   . ILE B  1 260 ? 31.83951 3.44947   -52.28115 1.000 12.76983 ? 260 ILE B N   1 
ATOM   6178 C  CA  . ILE B  1 260 ? 32.48380 4.62010   -51.69521 1.000 11.52904 ? 260 ILE B CA  1 
ATOM   6179 C  C   . ILE B  1 260 ? 33.52466 4.13500   -50.69695 1.000 14.44953 ? 260 ILE B C   1 
ATOM   6180 O  O   . ILE B  1 260 ? 33.24437 3.24964   -49.87877 1.000 15.71288 ? 260 ILE B O   1 
ATOM   6181 C  CB  . ILE B  1 260 ? 31.46031 5.54335   -51.01140 1.000 12.51075 ? 260 ILE B CB  1 
ATOM   6182 C  CG1 . ILE B  1 260 ? 30.39452 6.00338   -52.00625 1.000 14.38763 ? 260 ILE B CG1 1 
ATOM   6183 C  CG2 . ILE B  1 260 ? 32.15768 6.74405   -50.38338 1.000 10.72325 ? 260 ILE B CG2 1 
ATOM   6184 C  CD1 . ILE B  1 260 ? 29.31377 6.85812   -51.38285 1.000 6.67228  ? 260 ILE B CD1 1 
ATOM   6185 N  N   . PHE B  1 261 ? 34.72075 4.71069   -50.75732 1.000 13.20717 ? 261 PHE B N   1 
ATOM   6186 C  CA  . PHE B  1 261 ? 35.82384 4.30341   -49.90103 1.000 14.59725 ? 261 PHE B CA  1 
ATOM   6187 C  C   . PHE B  1 261 ? 36.00230 5.27099   -48.73765 1.000 13.22691 ? 261 PHE B C   1 
ATOM   6188 O  O   . PHE B  1 261 ? 35.65131 6.45047   -48.82250 1.000 14.34149 ? 261 PHE B O   1 
ATOM   6189 C  CB  . PHE B  1 261 ? 37.13024 4.22262   -50.69292 1.000 13.71556 ? 261 PHE B CB  1 
ATOM   6190 C  CG  . PHE B  1 261 ? 37.16354 3.11434   -51.70145 1.000 13.79649 ? 261 PHE B CG  1 
ATOM   6191 C  CD1 . PHE B  1 261 ? 37.45048 1.81699   -51.31274 1.000 17.54657 ? 261 PHE B CD1 1 
ATOM   6192 C  CD2 . PHE B  1 261 ? 36.92352 3.37079   -53.04065 1.000 14.71620 ? 261 PHE B CD2 1 
ATOM   6193 C  CE1 . PHE B  1 261 ? 37.49090 0.79505   -52.23913 1.000 17.32881 ? 261 PHE B CE1 1 
ATOM   6194 C  CE2 . PHE B  1 261 ? 36.95934 2.35236   -53.97244 1.000 17.30311 ? 261 PHE B CE2 1 
ATOM   6195 C  CZ  . PHE B  1 261 ? 37.24423 1.06270   -53.57111 1.000 21.93125 ? 261 PHE B CZ  1 
ATOM   6196 N  N   . GLU B  1 262 ? 36.55723 4.75214   -47.64266 1.000 13.39187 ? 262 GLU B N   1 
ATOM   6197 C  CA  . GLU B  1 262 ? 37.02697 5.56164   -46.51771 1.000 16.62283 ? 262 GLU B CA  1 
ATOM   6198 C  C   . GLU B  1 262 ? 38.45546 5.10552   -46.23954 1.000 13.14792 ? 262 GLU B C   1 
ATOM   6199 O  O   . GLU B  1 262 ? 38.68206 4.17400   -45.46331 1.000 13.90597 ? 262 GLU B O   1 
ATOM   6200 C  CB  . GLU B  1 262 ? 36.13088 5.42180   -45.29229 1.000 15.22060 ? 262 GLU B CB  1 
ATOM   6201 C  CG  . GLU B  1 262 ? 36.58881 6.27829   -44.11945 1.000 22.51502 ? 262 GLU B CG  1 
ATOM   6202 C  CD  . GLU B  1 262 ? 35.51431 6.46632   -43.06814 1.000 23.37604 ? 262 GLU B CD  1 
ATOM   6203 O  OE1 . GLU B  1 262 ? 34.53928 5.68751   -43.06213 1.000 26.10573 ? 262 GLU B OE1 1 
ATOM   6204 O  OE2 . GLU B  1 262 ? 35.64308 7.39993   -42.24976 1.000 22.31614 ? 262 GLU B OE2 1 
ATOM   6205 N  N   . LEU B  1 263 ? 39.41578 5.76368   -46.88150 1.000 13.92179 ? 263 LEU B N   1 
ATOM   6206 C  CA  . LEU B  1 263 ? 40.80127 5.32169   -46.83496 1.000 19.73212 ? 263 LEU B CA  1 
ATOM   6207 C  C   . LEU B  1 263 ? 41.50163 5.83350   -45.58292 1.000 21.58681 ? 263 LEU B C   1 
ATOM   6208 O  O   . LEU B  1 263 ? 41.26569 6.95894   -45.13486 1.000 17.00841 ? 263 LEU B O   1 
ATOM   6209 C  CB  . LEU B  1 263 ? 41.55070 5.79721   -48.07958 1.000 15.43679 ? 263 LEU B CB  1 
ATOM   6210 C  CG  . LEU B  1 263 ? 40.90515 5.46057   -49.42454 1.000 15.29885 ? 263 LEU B CG  1 
ATOM   6211 C  CD1 . LEU B  1 263 ? 41.80012 5.89540   -50.57509 1.000 7.89611  ? 263 LEU B CD1 1 
ATOM   6212 C  CD2 . LEU B  1 263 ? 40.59021 3.97665   -49.51324 1.000 17.28240 ? 263 LEU B CD2 1 
ATOM   6213 N  N   . TYR B  1 264 ? 42.37016 4.99503   -45.02228 1.000 21.97458 ? 264 TYR B N   1 
ATOM   6214 C  CA  . TYR B  1 264 ? 43.21295 5.38990   -43.90230 1.000 23.03321 ? 264 TYR B CA  1 
ATOM   6215 C  C   . TYR B  1 264 ? 44.40583 4.44853   -43.84163 1.000 19.52293 ? 264 TYR B C   1 
ATOM   6216 O  O   . TYR B  1 264 ? 44.39308 3.36176   -44.42521 1.000 20.63895 ? 264 TYR B O   1 
ATOM   6217 C  CB  . TYR B  1 264 ? 42.44303 5.38006   -42.57499 1.000 20.43680 ? 264 TYR B CB  1 
ATOM   6218 C  CG  . TYR B  1 264 ? 42.04500 4.00333   -42.08854 1.000 21.75037 ? 264 TYR B CG  1 
ATOM   6219 C  CD1 . TYR B  1 264 ? 40.86742 3.40610   -42.51945 1.000 18.48867 ? 264 TYR B CD1 1 
ATOM   6220 C  CD2 . TYR B  1 264 ? 42.84231 3.30508   -41.18794 1.000 26.71900 ? 264 TYR B CD2 1 
ATOM   6221 C  CE1 . TYR B  1 264 ? 40.49852 2.14861   -42.07466 1.000 17.54149 ? 264 TYR B CE1 1 
ATOM   6222 C  CE2 . TYR B  1 264 ? 42.48192 2.04742   -40.73770 1.000 21.22714 ? 264 TYR B CE2 1 
ATOM   6223 C  CZ  . TYR B  1 264 ? 41.30890 1.47522   -41.18261 1.000 21.04851 ? 264 TYR B CZ  1 
ATOM   6224 O  OH  . TYR B  1 264 ? 40.94808 0.22368   -40.73820 1.000 15.99640 ? 264 TYR B OH  1 
ATOM   6225 N  N   . PHE B  1 265 ? 45.43911 4.88438   -43.13004 1.000 20.70563 ? 265 PHE B N   1 
ATOM   6226 C  CA  . PHE B  1 265 ? 46.63568 4.08532   -42.91249 1.000 21.10052 ? 265 PHE B CA  1 
ATOM   6227 C  C   . PHE B  1 265 ? 46.55558 3.39474   -41.55814 1.000 23.20093 ? 265 PHE B C   1 
ATOM   6228 O  O   . PHE B  1 265 ? 46.10974 3.98989   -40.57271 1.000 25.05801 ? 265 PHE B O   1 
ATOM   6229 C  CB  . PHE B  1 265 ? 47.89313 4.95459   -42.98301 1.000 22.66078 ? 265 PHE B CB  1 
ATOM   6230 C  CG  . PHE B  1 265 ? 48.29761 5.32659   -44.38122 1.000 19.28349 ? 265 PHE B CG  1 
ATOM   6231 C  CD1 . PHE B  1 265 ? 48.28280 4.38310   -45.39591 1.000 20.53752 ? 265 PHE B CD1 1 
ATOM   6232 C  CD2 . PHE B  1 265 ? 48.68921 6.61900   -44.68144 1.000 16.59236 ? 265 PHE B CD2 1 
ATOM   6233 C  CE1 . PHE B  1 265 ? 48.65571 4.72057   -46.68222 1.000 16.63903 ? 265 PHE B CE1 1 
ATOM   6234 C  CE2 . PHE B  1 265 ? 49.06260 6.96350   -45.96698 1.000 26.60262 ? 265 PHE B CE2 1 
ATOM   6235 C  CZ  . PHE B  1 265 ? 49.04448 6.01300   -46.96879 1.000 21.24997 ? 265 PHE B CZ  1 
ATOM   6236 N  N   . ASP B  1 266 ? 46.98774 2.13242   -41.51411 1.000 25.58374 ? 266 ASP B N   1 
ATOM   6237 C  CA  . ASP B  1 266 ? 46.99903 1.39428   -40.25558 1.000 26.74879 ? 266 ASP B CA  1 
ATOM   6238 C  C   . ASP B  1 266 ? 48.11844 1.83805   -39.32224 1.000 28.53676 ? 266 ASP B C   1 
ATOM   6239 O  O   . ASP B  1 266 ? 48.25333 1.26899   -38.23300 1.000 37.17072 ? 266 ASP B O   1 
ATOM   6240 C  CB  . ASP B  1 266 ? 47.09845 -0.11057  -40.52241 1.000 21.55192 ? 266 ASP B CB  1 
ATOM   6241 C  CG  . ASP B  1 266 ? 48.41178 -0.50842  -41.16402 1.000 27.18244 ? 266 ASP B CG  1 
ATOM   6242 O  OD1 . ASP B  1 266 ? 49.05075 0.35023   -41.80773 1.000 28.79868 ? 266 ASP B OD1 1 
ATOM   6243 O  OD2 . ASP B  1 266 ? 48.80256 -1.68707  -41.02892 1.000 27.06432 ? 266 ASP B OD2 1 
ATOM   6244 N  N   . HIS B  1 267 ? 48.91809 2.82107   -39.72276 1.000 19.87673 ? 267 HIS B N   1 
ATOM   6245 C  CA  . HIS B  1 267 ? 49.86763 3.49973   -38.85688 1.000 30.11571 ? 267 HIS B CA  1 
ATOM   6246 C  C   . HIS B  1 267 ? 49.44431 4.95559   -38.68884 1.000 33.21310 ? 267 HIS B C   1 
ATOM   6247 O  O   . HIS B  1 267 ? 48.55984 5.45778   -39.38154 1.000 36.97321 ? 267 HIS B O   1 
ATOM   6248 C  CB  . HIS B  1 267 ? 51.28987 3.41489   -39.42740 1.000 26.81793 ? 267 HIS B CB  1 
ATOM   6249 C  CG  . HIS B  1 267 ? 51.85766 2.02907   -39.44026 1.000 26.84136 ? 267 HIS B CG  1 
ATOM   6250 N  ND1 . HIS B  1 267 ? 52.75858 1.58707   -38.49564 1.000 27.59455 ? 267 HIS B ND1 1 
ATOM   6251 C  CD2 . HIS B  1 267 ? 51.65831 0.98939   -40.28504 1.000 29.04995 ? 267 HIS B CD2 1 
ATOM   6252 C  CE1 . HIS B  1 267 ? 53.08827 0.33485   -38.75628 1.000 24.62750 ? 267 HIS B CE1 1 
ATOM   6253 N  NE2 . HIS B  1 267 ? 52.43445 -0.05166  -39.83682 1.000 23.30208 ? 267 HIS B NE2 1 
ATOM   6254 N  N   . ASP B  1 268 ? 50.09143 5.64227   -37.74714 1.000 35.95941 ? 268 ASP B N   1 
ATOM   6255 C  CA  . ASP B  1 268 ? 49.80981 7.05325   -37.48579 1.000 32.47500 ? 268 ASP B CA  1 
ATOM   6256 C  C   . ASP B  1 268 ? 50.48696 7.90053   -38.56247 1.000 33.70071 ? 268 ASP B C   1 
ATOM   6257 O  O   . ASP B  1 268 ? 51.47281 8.60186   -38.32568 1.000 33.89503 ? 268 ASP B O   1 
ATOM   6258 C  CB  . ASP B  1 268 ? 50.28576 7.44772   -36.09676 1.000 32.16239 ? 268 ASP B CB  1 
ATOM   6259 C  CG  . ASP B  1 268 ? 49.95316 8.88944   -35.74480 1.000 41.51707 ? 268 ASP B CG  1 
ATOM   6260 O  OD1 . ASP B  1 268 ? 50.50218 9.39762   -34.74104 1.000 58.03396 ? 268 ASP B OD1 1 
ATOM   6261 O  OD2 . ASP B  1 268 ? 49.14776 9.51291   -36.47084 1.000 48.70055 ? 268 ASP B OD2 1 
ATOM   6262 N  N   . ILE B  1 269 ? 49.93281 7.82218   -39.76750 1.000 31.30161 ? 269 ILE B N   1 
ATOM   6263 C  CA  . ILE B  1 269 ? 50.42838 8.56489   -40.91893 1.000 29.06012 ? 269 ILE B CA  1 
ATOM   6264 C  C   . ILE B  1 269 ? 49.26758 9.34682   -41.51193 1.000 27.29244 ? 269 ILE B C   1 
ATOM   6265 O  O   . ILE B  1 269 ? 48.19376 8.78494   -41.75390 1.000 30.97410 ? 269 ILE B O   1 
ATOM   6266 C  CB  . ILE B  1 269 ? 51.06249 7.63808   -41.97057 1.000 31.72620 ? 269 ILE B CB  1 
ATOM   6267 C  CG1 . ILE B  1 269 ? 52.29068 6.94622   -41.37627 1.000 26.18980 ? 269 ILE B CG1 1 
ATOM   6268 C  CG2 . ILE B  1 269 ? 51.42997 8.42095   -43.18832 1.000 25.89692 ? 269 ILE B CG2 1 
ATOM   6269 C  CD1 . ILE B  1 269 ? 53.06214 6.10851   -42.37462 1.000 22.20520 ? 269 ILE B CD1 1 
ATOM   6270 N  N   . THR B  1 270 ? 49.48362 10.64012  -41.73182 1.000 25.35035 ? 270 THR B N   1 
ATOM   6271 C  CA  . THR B  1 270 ? 48.43511 11.57373  -42.10906 1.000 26.31952 ? 270 THR B CA  1 
ATOM   6272 C  C   . THR B  1 270 ? 48.49099 11.88396  -43.59989 1.000 27.11667 ? 270 THR B C   1 
ATOM   6273 O  O   . THR B  1 270 ? 49.57278 12.00556  -44.18408 1.000 25.93884 ? 270 THR B O   1 
ATOM   6274 C  CB  . THR B  1 270 ? 48.57085 12.87036  -41.30674 1.000 27.58744 ? 270 THR B CB  1 
ATOM   6275 O  OG1 . THR B  1 270 ? 48.70667 12.56140  -39.91272 1.000 36.58478 ? 270 THR B OG1 1 
ATOM   6276 C  CG2 . THR B  1 270 ? 47.34756 13.74565  -41.50087 1.000 33.61929 ? 270 THR B CG2 1 
ATOM   6277 N  N   . PHE B  1 271 ? 47.31457 12.01309  -44.20795 1.000 28.16233 ? 271 PHE B N   1 
ATOM   6278 C  CA  . PHE B  1 271 ? 47.21058 12.52948  -45.56398 1.000 18.86960 ? 271 PHE B CA  1 
ATOM   6279 C  C   . PHE B  1 271 ? 47.25844 14.05194  -45.53267 1.000 22.24149 ? 271 PHE B C   1 
ATOM   6280 O  O   . PHE B  1 271 ? 46.52935 14.68842  -44.76463 1.000 26.85855 ? 271 PHE B O   1 
ATOM   6281 C  CB  . PHE B  1 271 ? 45.91044 12.07226  -46.22690 1.000 15.22686 ? 271 PHE B CB  1 
ATOM   6282 C  CG  . PHE B  1 271 ? 45.68244 10.58964  -46.18045 1.000 20.11167 ? 271 PHE B CG  1 
ATOM   6283 C  CD1 . PHE B  1 271 ? 46.37364 9.74005   -47.02740 1.000 21.85247 ? 271 PHE B CD1 1 
ATOM   6284 C  CD2 . PHE B  1 271 ? 44.75525 10.04796  -45.30582 1.000 21.84483 ? 271 PHE B CD2 1 
ATOM   6285 C  CE1 . PHE B  1 271 ? 46.15711 8.37653   -46.99148 1.000 21.88874 ? 271 PHE B CE1 1 
ATOM   6286 C  CE2 . PHE B  1 271 ? 44.53400 8.68514   -45.26397 1.000 22.88910 ? 271 PHE B CE2 1 
ATOM   6287 C  CZ  . PHE B  1 271 ? 45.23589 7.84809   -46.10796 1.000 27.98481 ? 271 PHE B CZ  1 
ATOM   6288 N  N   . HIS B  1 272 ? 48.11541 14.63476  -46.36292 1.000 17.14689 ? 272 HIS B N   1 
ATOM   6289 C  CA  . HIS B  1 272 ? 48.16313 16.08111  -46.56385 1.000 16.36298 ? 272 HIS B CA  1 
ATOM   6290 C  C   . HIS B  1 272 ? 47.57180 16.34742  -47.94606 1.000 16.15616 ? 272 HIS B C   1 
ATOM   6291 O  O   . HIS B  1 272 ? 48.26709 16.28152  -48.96093 1.000 17.97805 ? 272 HIS B O   1 
ATOM   6292 C  CB  . HIS B  1 272 ? 49.58699 16.62209  -46.44071 1.000 21.68846 ? 272 HIS B CB  1 
ATOM   6293 C  CG  . HIS B  1 272 ? 50.21014 16.38923  -45.09971 1.000 21.20807 ? 272 HIS B CG  1 
ATOM   6294 N  ND1 . HIS B  1 272 ? 50.89269 15.23334  -44.78636 1.000 23.99784 ? 272 HIS B ND1 1 
ATOM   6295 C  CD2 . HIS B  1 272 ? 50.25477 17.16474  -43.99059 1.000 19.59810 ? 272 HIS B CD2 1 
ATOM   6296 C  CE1 . HIS B  1 272 ? 51.33070 15.30650  -43.54216 1.000 22.53990 ? 272 HIS B CE1 1 
ATOM   6297 N  NE2 . HIS B  1 272 ? 50.95604 16.46796  -43.03661 1.000 24.88956 ? 272 HIS B NE2 1 
ATOM   6298 N  N   . GLN B  1 273 ? 46.27462 16.64081  -47.98053 1.000 13.92467 ? 273 GLN B N   1 
ATOM   6299 C  CA  . GLN B  1 273 ? 45.57451 16.82882  -49.24408 1.000 16.40798 ? 273 GLN B CA  1 
ATOM   6300 C  C   . GLN B  1 273 ? 45.90113 18.20195  -49.81708 1.000 14.16125 ? 273 GLN B C   1 
ATOM   6301 O  O   . GLN B  1 273 ? 45.70640 19.22626  -49.15332 1.000 14.77900 ? 273 GLN B O   1 
ATOM   6302 C  CB  . GLN B  1 273 ? 44.06932 16.66150  -49.05587 1.000 15.56720 ? 273 GLN B CB  1 
ATOM   6303 C  CG  . GLN B  1 273 ? 43.27802 16.82389  -50.34043 1.000 12.50087 ? 273 GLN B CG  1 
ATOM   6304 C  CD  . GLN B  1 273 ? 41.97809 16.04844  -50.32739 1.000 12.96420 ? 273 GLN B CD  1 
ATOM   6305 O  OE1 . GLN B  1 273 ? 41.56718 15.51431  -49.29604 1.000 9.40858  ? 273 GLN B OE1 1 
ATOM   6306 N  NE2 . GLN B  1 273 ? 41.32578 15.97436  -51.48099 1.000 16.22966 ? 273 GLN B NE2 1 
ATOM   6307 N  N   . ILE B  1 274 ? 46.39719 18.21843  -51.05261 1.000 13.35792 ? 274 ILE B N   1 
ATOM   6308 C  CA  . ILE B  1 274 ? 46.78135 19.45646  -51.72131 1.000 12.89101 ? 274 ILE B CA  1 
ATOM   6309 C  C   . ILE B  1 274 ? 45.86763 19.81043  -52.88212 1.000 14.53845 ? 274 ILE B C   1 
ATOM   6310 O  O   . ILE B  1 274 ? 45.95831 20.93817  -53.39448 1.000 15.81566 ? 274 ILE B O   1 
ATOM   6311 C  CB  . ILE B  1 274 ? 48.24364 19.40107  -52.21022 1.000 11.99785 ? 274 ILE B CB  1 
ATOM   6312 C  CG1 . ILE B  1 274 ? 48.42683 18.23587  -53.18422 1.000 12.24757 ? 274 ILE B CG1 1 
ATOM   6313 C  CG2 . ILE B  1 274 ? 49.19778 19.27620  -51.03311 1.000 10.65477 ? 274 ILE B CG2 1 
ATOM   6314 C  CD1 . ILE B  1 274 ? 49.80265 18.15672  -53.80499 1.000 14.80996 ? 274 ILE B CD1 1 
ATOM   6315 N  N   . GLY B  1 275 ? 44.99996 18.90061  -53.31884 1.000 12.67677 ? 275 GLY B N   1 
ATOM   6316 C  CA  . GLY B  1 275 ? 44.16174 19.17341  -54.46972 1.000 13.87342 ? 275 GLY B CA  1 
ATOM   6317 C  C   . GLY B  1 275 ? 42.93495 18.29473  -54.50117 1.000 13.80684 ? 275 GLY B C   1 
ATOM   6318 O  O   . GLY B  1 275 ? 42.87440 17.24414  -53.85329 1.000 10.36083 ? 275 GLY B O   1 
ATOM   6319 N  N   . THR B  1 276 ? 41.94498 18.74851  -55.26951 1.000 16.18430 ? 276 THR B N   1 
ATOM   6320 C  CA  . THR B  1 276 ? 40.69693 18.01697  -55.43344 1.000 13.28353 ? 276 THR B CA  1 
ATOM   6321 C  C   . THR B  1 276 ? 40.43797 17.74162  -56.90806 1.000 11.74814 ? 276 THR B C   1 
ATOM   6322 O  O   . THR B  1 276 ? 41.37472 17.71874  -57.71399 1.000 15.79286 ? 276 THR B O   1 
ATOM   6323 C  CB  . THR B  1 276 ? 39.53176 18.79515  -54.81356 1.000 13.80941 ? 276 THR B CB  1 
ATOM   6324 O  OG1 . THR B  1 276 ? 39.45125 20.09962  -55.40099 1.000 11.98657 ? 276 THR B OG1 1 
ATOM   6325 C  CG2 . THR B  1 276 ? 39.71754 18.93614  -53.30173 1.000 16.64576 ? 276 THR B CG2 1 
ATOM   6326 N  N   . ASP B  1 277 ? 39.16850 17.53912  -57.26643 1.000 10.74613 ? 277 ASP B N   1 
ATOM   6327 C  CA  . ASP B  1 277 ? 38.82498 17.22484  -58.64886 1.000 11.13857 ? 277 ASP B CA  1 
ATOM   6328 C  C   . ASP B  1 277 ? 39.25166 18.33433  -59.60143 1.000 12.80773 ? 277 ASP B C   1 
ATOM   6329 O  O   . ASP B  1 277 ? 39.77976 18.06141  -60.68598 1.000 12.63949 ? 277 ASP B O   1 
ATOM   6330 C  CB  . ASP B  1 277 ? 37.32121 16.98152  -58.76887 1.000 13.65927 ? 277 ASP B CB  1 
ATOM   6331 C  CG  . ASP B  1 277 ? 36.79821 16.01292  -57.72384 1.000 12.72210 ? 277 ASP B CG  1 
ATOM   6332 O  OD1 . ASP B  1 277 ? 37.62076 15.37680  -57.03015 1.000 12.89923 ? 277 ASP B OD1 1 
ATOM   6333 O  OD2 . ASP B  1 277 ? 35.56022 15.89558  -57.59099 1.000 10.90493 ? 277 ASP B OD2 1 
ATOM   6334 N  N   . GLY B  1 278 ? 39.02112 19.59365  -59.22498 1.000 13.46878 ? 278 GLY B N   1 
ATOM   6335 C  CA  . GLY B  1 278 ? 39.27130 20.68206  -60.15194 1.000 11.87018 ? 278 GLY B CA  1 
ATOM   6336 C  C   . GLY B  1 278 ? 40.68236 21.22138  -60.13256 1.000 12.60013 ? 278 GLY B C   1 
ATOM   6337 O  O   . GLY B  1 278 ? 41.05910 21.96835  -61.04026 1.000 16.47125 ? 278 GLY B O   1 
ATOM   6338 N  N   . GLY B  1 279 ? 41.46521 20.88134  -59.12006 1.000 13.19948 ? 279 GLY B N   1 
ATOM   6339 C  CA  . GLY B  1 279 ? 42.84762 21.29933  -59.07647 1.000 17.06296 ? 279 GLY B CA  1 
ATOM   6340 C  C   . GLY B  1 279 ? 43.31011 21.51072  -57.64996 1.000 15.75177 ? 279 GLY B C   1 
ATOM   6341 O  O   . GLY B  1 279 ? 42.76474 20.93690  -56.71210 1.000 15.49041 ? 279 GLY B O   1 
ATOM   6342 N  N   . LEU B  1 280 ? 44.33472 22.34934  -57.52881 1.000 13.49335 ? 280 LEU B N   1 
ATOM   6343 C  CA  . LEU B  1 280 ? 45.00388 22.55758  -56.25394 1.000 14.35725 ? 280 LEU B CA  1 
ATOM   6344 C  C   . LEU B  1 280 ? 44.10953 23.30526  -55.27496 1.000 16.27148 ? 280 LEU B C   1 
ATOM   6345 O  O   . LEU B  1 280 ? 43.33226 24.18382  -55.65929 1.000 22.74057 ? 280 LEU B O   1 
ATOM   6346 C  CB  . LEU B  1 280 ? 46.30051 23.34330  -56.45841 1.000 17.96386 ? 280 LEU B CB  1 
ATOM   6347 C  CG  . LEU B  1 280 ? 47.38541 22.73445  -57.34694 1.000 18.47201 ? 280 LEU B CG  1 
ATOM   6348 C  CD1 . LEU B  1 280 ? 48.44944 23.76976  -57.66527 1.000 20.78080 ? 280 LEU B CD1 1 
ATOM   6349 C  CD2 . LEU B  1 280 ? 48.00362 21.52012  -56.67880 1.000 14.28961 ? 280 LEU B CD2 1 
ATOM   6350 N  N   . LEU B  1 281 ? 44.22872 22.95074  -53.99813 1.000 13.71346 ? 281 LEU B N   1 
ATOM   6351 C  CA  . LEU B  1 281 ? 43.64753 23.75293  -52.93489 1.000 15.38070 ? 281 LEU B CA  1 
ATOM   6352 C  C   . LEU B  1 281 ? 44.47403 25.02318  -52.74272 1.000 18.17408 ? 281 LEU B C   1 
ATOM   6353 O  O   . LEU B  1 281 ? 45.48198 25.25368  -53.41592 1.000 21.81463 ? 281 LEU B O   1 
ATOM   6354 C  CB  . LEU B  1 281 ? 43.58178 22.95441  -51.63442 1.000 16.31942 ? 281 LEU B CB  1 
ATOM   6355 C  CG  . LEU B  1 281 ? 42.73973 21.67970  -51.60386 1.000 17.79482 ? 281 LEU B CG  1 
ATOM   6356 C  CD1 . LEU B  1 281 ? 42.82420 21.02529  -50.23547 1.000 13.01915 ? 281 LEU B CD1 1 
ATOM   6357 C  CD2 . LEU B  1 281 ? 41.30068 21.98985  -51.95745 1.000 18.31184 ? 281 LEU B CD2 1 
ATOM   6358 N  N   . GLN B  1 282 ? 44.04399 25.86244  -51.80205 1.000 19.12314 ? 282 GLN B N   1 
ATOM   6359 C  CA  . GLN B  1 282 ? 44.84464 27.03106  -51.45835 1.000 24.49894 ? 282 GLN B CA  1 
ATOM   6360 C  C   . GLN B  1 282 ? 45.92615 26.67944  -50.44475 1.000 24.69934 ? 282 GLN B C   1 
ATOM   6361 O  O   . GLN B  1 282 ? 47.04710 27.19404  -50.52479 1.000 24.89270 ? 282 GLN B O   1 
ATOM   6362 C  CB  . GLN B  1 282 ? 43.94662 28.14824  -50.92620 1.000 27.24992 ? 282 GLN B CB  1 
ATOM   6363 C  CG  . GLN B  1 282 ? 43.01598 28.73466  -51.97554 1.000 27.61145 ? 282 GLN B CG  1 
ATOM   6364 C  CD  . GLN B  1 282 ? 42.09428 29.79781  -51.41499 1.000 36.62773 ? 282 GLN B CD  1 
ATOM   6365 O  OE1 . GLN B  1 282 ? 42.28869 30.28180  -50.29956 1.000 51.69172 ? 282 GLN B OE1 1 
ATOM   6366 N  NE2 . GLN B  1 282 ? 41.07955 30.16601  -52.18829 1.000 45.75849 ? 282 GLN B NE2 1 
ATOM   6367 N  N   . HIS B  1 283 ? 45.61301 25.79929  -49.49955 1.000 22.42134 ? 283 HIS B N   1 
ATOM   6368 C  CA  . HIS B  1 283 ? 46.53626 25.37322  -48.46148 1.000 20.03512 ? 283 HIS B CA  1 
ATOM   6369 C  C   . HIS B  1 283 ? 46.35875 23.88158  -48.22704 1.000 18.77774 ? 283 HIS B C   1 
ATOM   6370 O  O   . HIS B  1 283 ? 45.24997 23.35559  -48.38146 1.000 19.51370 ? 283 HIS B O   1 
ATOM   6371 C  CB  . HIS B  1 283 ? 46.29820 26.13456  -47.14758 1.000 18.22498 ? 283 HIS B CB  1 
ATOM   6372 C  CG  . HIS B  1 283 ? 46.07739 27.60379  -47.33222 1.000 33.36349 ? 283 HIS B CG  1 
ATOM   6373 N  ND1 . HIS B  1 283 ? 47.11386 28.50188  -47.47160 1.000 37.47531 ? 283 HIS B ND1 1 
ATOM   6374 C  CD2 . HIS B  1 283 ? 44.93741 28.33151  -47.40331 1.000 43.23507 ? 283 HIS B CD2 1 
ATOM   6375 C  CE1 . HIS B  1 283 ? 46.62212 29.71931  -47.61945 1.000 37.57365 ? 283 HIS B CE1 1 
ATOM   6376 N  NE2 . HIS B  1 283 ? 45.30384 29.64357  -47.58188 1.000 41.50732 ? 283 HIS B NE2 1 
ATOM   6377 N  N   . PRO B  1 284 ? 47.42928 23.17407  -47.86715 1.000 17.90403 ? 284 PRO B N   1 
ATOM   6378 C  CA  . PRO B  1 284 ? 47.29478 21.74368  -47.56993 1.000 19.09332 ? 284 PRO B CA  1 
ATOM   6379 C  C   . PRO B  1 284 ? 46.39771 21.51340  -46.36432 1.000 18.22326 ? 284 PRO B C   1 
ATOM   6380 O  O   . PRO B  1 284 ? 46.34743 22.32123  -45.43461 1.000 22.79514 ? 284 PRO B O   1 
ATOM   6381 C  CB  . PRO B  1 284 ? 48.73495 21.29962  -47.28703 1.000 19.53418 ? 284 PRO B CB  1 
ATOM   6382 C  CG  . PRO B  1 284 ? 49.58603 22.32096  -47.95567 1.000 24.17528 ? 284 PRO B CG  1 
ATOM   6383 C  CD  . PRO B  1 284 ? 48.83388 23.61281  -47.84182 1.000 20.90578 ? 284 PRO B CD  1 
ATOM   6384 N  N   . VAL B  1 285 ? 45.68334 20.39194  -46.39007 1.000 15.65652 ? 285 VAL B N   1 
ATOM   6385 C  CA  . VAL B  1 285 ? 44.74345 20.02497  -45.33754 1.000 18.17232 ? 285 VAL B CA  1 
ATOM   6386 C  C   . VAL B  1 285 ? 45.18896 18.69627  -44.74421 1.000 20.70013 ? 285 VAL B C   1 
ATOM   6387 O  O   . VAL B  1 285 ? 45.25149 17.68342  -45.45250 1.000 20.30338 ? 285 VAL B O   1 
ATOM   6388 C  CB  . VAL B  1 285 ? 43.30209 19.93246  -45.86364 1.000 21.19021 ? 285 VAL B CB  1 
ATOM   6389 C  CG1 . VAL B  1 285 ? 42.35126 19.55044  -44.73970 1.000 17.83987 ? 285 VAL B CG1 1 
ATOM   6390 C  CG2 . VAL B  1 285 ? 42.88149 21.25015  -46.50009 1.000 15.42416 ? 285 VAL B CG2 1 
ATOM   6391 N  N   . LYS B  1 286 ? 45.50042 18.70188  -43.45040 1.000 22.98912 ? 286 LYS B N   1 
ATOM   6392 C  CA  . LYS B  1 286 ? 45.81769 17.46933  -42.74082 1.000 22.14800 ? 286 LYS B CA  1 
ATOM   6393 C  C   . LYS B  1 286 ? 44.53914 16.67292  -42.50850 1.000 24.41370 ? 286 LYS B C   1 
ATOM   6394 O  O   . LYS B  1 286 ? 43.64086 17.12610  -41.79162 1.000 26.15439 ? 286 LYS B O   1 
ATOM   6395 C  CB  . LYS B  1 286 ? 46.50074 17.78441  -41.41189 1.000 21.64131 ? 286 LYS B CB  1 
ATOM   6396 C  CG  . LYS B  1 286 ? 47.92923 17.27890  -41.30032 1.000 26.17142 ? 286 LYS B CG  1 
ATOM   6397 C  CD  . LYS B  1 286 ? 48.41084 17.30663  -39.85665 1.000 43.70300 ? 286 LYS B CD  1 
ATOM   6398 C  CE  . LYS B  1 286 ? 49.74760 16.59387  -39.70244 1.000 54.77258 ? 286 LYS B CE  1 
ATOM   6399 N  NZ  . LYS B  1 286 ? 50.19144 16.53308  -38.28082 1.000 45.07149 ? 286 LYS B NZ  1 
ATOM   6400 N  N   . VAL B  1 287 ? 44.44661 15.49451  -43.12250 1.000 23.99229 ? 287 VAL B N   1 
ATOM   6401 C  CA  . VAL B  1 287 ? 43.28293 14.62680  -42.98466 1.000 31.34937 ? 287 VAL B CA  1 
ATOM   6402 C  C   . VAL B  1 287 ? 43.75432 13.23184  -42.59966 1.000 26.50272 ? 287 VAL B C   1 
ATOM   6403 O  O   . VAL B  1 287 ? 44.74287 12.72788  -43.14417 1.000 22.41889 ? 287 VAL B O   1 
ATOM   6404 C  CB  . VAL B  1 287 ? 42.44230 14.56768  -44.27954 1.000 27.23318 ? 287 VAL B CB  1 
ATOM   6405 C  CG1 . VAL B  1 287 ? 40.99444 14.23742  -43.95256 1.000 26.96788 ? 287 VAL B CG1 1 
ATOM   6406 C  CG2 . VAL B  1 287 ? 42.53644 15.87046  -45.05481 1.000 26.65861 ? 287 VAL B CG2 1 
ATOM   6407 N  N   . ASN B  1 288 ? 43.04115 12.60616  -41.66245 1.000 24.19338 ? 288 ASN B N   1 
ATOM   6408 C  CA  . ASN B  1 288 ? 43.33720 11.23670  -41.26305 1.000 23.87018 ? 288 ASN B CA  1 
ATOM   6409 C  C   . ASN B  1 288 ? 42.61028 10.19718  -42.10377 1.000 21.75664 ? 288 ASN B C   1 
ATOM   6410 O  O   . ASN B  1 288 ? 43.07380 9.05399   -42.18527 1.000 20.53417 ? 288 ASN B O   1 
ATOM   6411 C  CB  . ASN B  1 288 ? 42.98118 11.02047  -39.78854 1.000 22.70715 ? 288 ASN B CB  1 
ATOM   6412 C  CG  . ASN B  1 288 ? 44.04739 11.54210  -38.84890 1.000 32.86233 ? 288 ASN B CG  1 
ATOM   6413 O  OD1 . ASN B  1 288 ? 45.00135 10.83582  -38.52366 1.000 42.27076 ? 288 ASN B OD1 1 
ATOM   6414 N  ND2 . ASN B  1 288 ? 43.89007 12.78281  -38.40331 1.000 42.19861 ? 288 ASN B ND2 1 
ATOM   6415 N  N   . GLU B  1 289 ? 41.48832 10.55758  -42.72290 1.000 20.56625 ? 289 GLU B N   1 
ATOM   6416 C  CA  . GLU B  1 289 ? 40.70609 9.61796   -43.51137 1.000 22.28271 ? 289 GLU B CA  1 
ATOM   6417 C  C   . GLU B  1 289 ? 40.13074 10.31959  -44.73091 1.000 22.51359 ? 289 GLU B C   1 
ATOM   6418 O  O   . GLU B  1 289 ? 39.62632 11.44143  -44.63298 1.000 26.24753 ? 289 GLU B O   1 
ATOM   6419 C  CB  . GLU B  1 289 ? 39.57498 8.99498   -42.68335 1.000 18.04496 ? 289 GLU B CB  1 
ATOM   6420 C  CG  . GLU B  1 289 ? 40.04452 7.94173   -41.69695 1.000 23.54499 ? 289 GLU B CG  1 
ATOM   6421 C  CD  . GLU B  1 289 ? 38.90844 7.34931   -40.89327 1.000 28.39598 ? 289 GLU B CD  1 
ATOM   6422 O  OE1 . GLU B  1 289 ? 37.88579 8.04210   -40.71367 1.000 29.31252 ? 289 GLU B OE1 1 
ATOM   6423 O  OE2 . GLU B  1 289 ? 39.03676 6.19075   -40.44432 1.000 29.31855 ? 289 GLU B OE2 1 
ATOM   6424 N  N   . LEU B  1 290 ? 40.20631 9.64828   -45.87617 1.000 17.16308 ? 290 LEU B N   1 
ATOM   6425 C  CA  . LEU B  1 290 ? 39.69400 10.16614  -47.13784 1.000 19.67596 ? 290 LEU B CA  1 
ATOM   6426 C  C   . LEU B  1 290 ? 38.41685 9.42311   -47.50181 1.000 13.60745 ? 290 LEU B C   1 
ATOM   6427 O  O   . LEU B  1 290 ? 38.44479 8.20813   -47.72518 1.000 12.80588 ? 290 LEU B O   1 
ATOM   6428 C  CB  . LEU B  1 290 ? 40.72752 10.01614  -48.25383 1.000 16.54363 ? 290 LEU B CB  1 
ATOM   6429 C  CG  . LEU B  1 290 ? 41.96369 10.90927  -48.19710 1.000 15.51031 ? 290 LEU B CG  1 
ATOM   6430 C  CD1 . LEU B  1 290 ? 42.89218 10.58047  -49.35421 1.000 22.62664 ? 290 LEU B CD1 1 
ATOM   6431 C  CD2 . LEU B  1 290 ? 41.56293 12.37405  -48.22726 1.000 15.60871 ? 290 LEU B CD2 1 
ATOM   6432 N  N   . VAL B  1 291 ? 37.30614 10.14979  -47.56147 1.000 11.19031 ? 291 VAL B N   1 
ATOM   6433 C  CA  . VAL B  1 291 ? 36.05074 9.61028   -48.07063 1.000 13.06244 ? 291 VAL B CA  1 
ATOM   6434 C  C   . VAL B  1 291 ? 35.97888 9.96852   -49.55006 1.000 10.09945 ? 291 VAL B C   1 
ATOM   6435 O  O   . VAL B  1 291 ? 35.83439 11.14016  -49.90749 1.000 10.83500 ? 291 VAL B O   1 
ATOM   6436 C  CB  . VAL B  1 291 ? 34.84252 10.15553  -47.30049 1.000 13.11087 ? 291 VAL B CB  1 
ATOM   6437 C  CG1 . VAL B  1 291 ? 33.55481 9.55511   -47.84412 1.000 7.13255  ? 291 VAL B CG1 1 
ATOM   6438 C  CG2 . VAL B  1 291 ? 34.98594 9.86355   -45.81297 1.000 9.81603  ? 291 VAL B CG2 1 
ATOM   6439 N  N   . ILE B  1 292 ? 36.09469 8.96197   -50.41202 1.000 9.87915  ? 292 ILE B N   1 
ATOM   6440 C  CA  . ILE B  1 292 ? 36.18286 9.15870   -51.85496 1.000 11.60719 ? 292 ILE B CA  1 
ATOM   6441 C  C   . ILE B  1 292 ? 35.07050 8.35175   -52.51042 1.000 11.18619 ? 292 ILE B C   1 
ATOM   6442 O  O   . ILE B  1 292 ? 35.12259 7.11515   -52.53693 1.000 13.93099 ? 292 ILE B O   1 
ATOM   6443 C  CB  . ILE B  1 292 ? 37.55473 8.74839   -52.40635 1.000 15.73405 ? 292 ILE B CB  1 
ATOM   6444 C  CG1 . ILE B  1 292 ? 38.67428 9.34598   -51.55318 1.000 11.63338 ? 292 ILE B CG1 1 
ATOM   6445 C  CG2 . ILE B  1 292 ? 37.70216 9.19248   -53.85442 1.000 13.91288 ? 292 ILE B CG2 1 
ATOM   6446 C  CD1 . ILE B  1 292 ? 40.05594 8.89530   -51.96331 1.000 15.97817 ? 292 ILE B CD1 1 
ATOM   6447 N  N   . ALA B  1 293 ? 34.06999 9.04561   -53.03872 1.000 9.99918  ? 293 ALA B N   1 
ATOM   6448 C  CA  . ALA B  1 293 ? 32.99459 8.41673   -53.78960 1.000 10.96509 ? 293 ALA B CA  1 
ATOM   6449 C  C   . ALA B  1 293 ? 33.45097 8.16101   -55.22137 1.000 15.13183 ? 293 ALA B C   1 
ATOM   6450 O  O   . ALA B  1 293 ? 34.50993 8.63609   -55.63858 1.000 14.89857 ? 293 ALA B O   1 
ATOM   6451 C  CB  . ALA B  1 293 ? 31.75550 9.30740   -53.74873 1.000 13.66397 ? 293 ALA B CB  1 
ATOM   6452 N  N   . PRO B  1 294 ? 32.68665 7.38725   -55.99755 1.000 13.55308 ? 294 PRO B N   1 
ATOM   6453 C  CA  . PRO B  1 294 ? 33.04817 7.17892   -57.40505 1.000 16.02747 ? 294 PRO B CA  1 
ATOM   6454 C  C   . PRO B  1 294 ? 33.22859 8.49575   -58.14923 1.000 14.79657 ? 294 PRO B C   1 
ATOM   6455 O  O   . PRO B  1 294 ? 32.43854 9.43069   -57.99721 1.000 14.60119 ? 294 PRO B O   1 
ATOM   6456 C  CB  . PRO B  1 294 ? 31.86428 6.37808   -57.95497 1.000 12.02481 ? 294 PRO B CB  1 
ATOM   6457 C  CG  . PRO B  1 294 ? 31.37749 5.61042   -56.78553 1.000 10.52143 ? 294 PRO B CG  1 
ATOM   6458 C  CD  . PRO B  1 294 ? 31.58365 6.49700   -55.58522 1.000 10.01785 ? 294 PRO B CD  1 
ATOM   6459 N  N   . ALA B  1 295 ? 34.29618 8.55763   -58.94764 1.000 11.99664 ? 295 ALA B N   1 
ATOM   6460 C  CA  . ALA B  1 295 ? 34.72158 9.64643   -59.82088 1.000 11.87343 ? 295 ALA B CA  1 
ATOM   6461 C  C   . ALA B  1 295 ? 35.43014 10.77016  -59.06606 1.000 14.73289 ? 295 ALA B C   1 
ATOM   6462 O  O   . ALA B  1 295 ? 35.99584 11.65460  -59.71058 1.000 15.30603 ? 295 ALA B O   1 
ATOM   6463 C  CB  . ALA B  1 295 ? 33.57165 10.25536  -60.64632 1.000 12.05463 ? 295 ALA B CB  1 
ATOM   6464 N  N   . GLU B  1 296 ? 35.42311 10.77770  -57.73627 1.000 12.43475 ? 296 GLU B N   1 
ATOM   6465 C  CA  . GLU B  1 296 ? 36.15942 11.79615  -57.00204 1.000 13.15845 ? 296 GLU B CA  1 
ATOM   6466 C  C   . GLU B  1 296 ? 37.65882 11.52504  -57.06320 1.000 12.04268 ? 296 GLU B C   1 
ATOM   6467 O  O   . GLU B  1 296 ? 38.10431 10.37708  -57.14829 1.000 12.43290 ? 296 GLU B O   1 
ATOM   6468 C  CB  . GLU B  1 296 ? 35.70054 11.84937  -55.54591 1.000 11.19148 ? 296 GLU B CB  1 
ATOM   6469 C  CG  . GLU B  1 296 ? 34.34952 12.50394  -55.34191 1.000 11.04699 ? 296 GLU B CG  1 
ATOM   6470 C  CD  . GLU B  1 296 ? 34.01762 12.69525  -53.87683 1.000 14.48016 ? 296 GLU B CD  1 
ATOM   6471 O  OE1 . GLU B  1 296 ? 33.92415 11.68413  -53.14845 1.000 12.87318 ? 296 GLU B OE1 1 
ATOM   6472 O  OE2 . GLU B  1 296 ? 33.86385 13.86005  -53.45070 1.000 13.79485 ? 296 GLU B OE2 1 
ATOM   6473 N  N   . ARG B  1 297 ? 38.43956 12.60197  -57.02351 1.000 9.12692  ? 297 ARG B N   1 
ATOM   6474 C  CA  . ARG B  1 297 ? 39.89234 12.52257  -57.01453 1.000 11.10290 ? 297 ARG B CA  1 
ATOM   6475 C  C   . ARG B  1 297 ? 40.43776 13.25464  -55.79604 1.000 11.07233 ? 297 ARG B C   1 
ATOM   6476 O  O   . ARG B  1 297 ? 39.84118 14.22275  -55.31491 1.000 11.56291 ? 297 ARG B O   1 
ATOM   6477 C  CB  . ARG B  1 297 ? 40.50529 13.11612  -58.29548 1.000 12.87653 ? 297 ARG B CB  1 
ATOM   6478 C  CG  . ARG B  1 297 ? 40.26352 12.29550  -59.55894 1.000 9.13365  ? 297 ARG B CG  1 
ATOM   6479 C  CD  . ARG B  1 297 ? 38.95895 12.67680  -60.23492 1.000 13.44654 ? 297 ARG B CD  1 
ATOM   6480 N  NE  . ARG B  1 297 ? 39.04050 13.96885  -60.90586 1.000 10.85220 ? 297 ARG B NE  1 
ATOM   6481 C  CZ  . ARG B  1 297 ? 37.98940 14.67337  -61.30236 1.000 10.69775 ? 297 ARG B CZ  1 
ATOM   6482 N  NH1 . ARG B  1 297 ? 36.75409 14.25408  -61.08362 1.000 9.43369  ? 297 ARG B NH1 1 
ATOM   6483 N  NH2 . ARG B  1 297 ? 38.18238 15.83128  -61.92761 1.000 14.93526 ? 297 ARG B NH2 1 
ATOM   6484 N  N   . CYS B  1 298 ? 41.57908 12.78191  -55.29785 1.000 8.75723  ? 298 CYS B N   1 
ATOM   6485 C  CA  . CYS B  1 298 ? 42.22173 13.37484  -54.12990 1.000 8.60967  ? 298 CYS B CA  1 
ATOM   6486 C  C   . CYS B  1 298 ? 43.72286 13.42212  -54.36148 1.000 11.65275 ? 298 CYS B C   1 
ATOM   6487 O  O   . CYS B  1 298 ? 44.36851 12.37593  -54.47704 1.000 11.47035 ? 298 CYS B O   1 
ATOM   6488 C  CB  . CYS B  1 298 ? 41.90162 12.58588  -52.85643 1.000 10.95124 ? 298 CYS B CB  1 
ATOM   6489 S  SG  . CYS B  1 298 ? 40.15109 12.54643  -52.42511 1.000 15.13051 ? 298 CYS B SG  1 
ATOM   6490 N  N   . ASP B  1 299 ? 44.26945 14.63365  -54.42627 1.000 13.21925 ? 299 ASP B N   1 
ATOM   6491 C  CA  . ASP B  1 299 ? 45.70472 14.85334  -54.57010 1.000 10.91063 ? 299 ASP B CA  1 
ATOM   6492 C  C   . ASP B  1 299 ? 46.29559 15.03358  -53.17540 1.000 15.81928 ? 299 ASP B C   1 
ATOM   6493 O  O   . ASP B  1 299 ? 46.07211 16.06216  -52.52847 1.000 16.42031 ? 299 ASP B O   1 
ATOM   6494 C  CB  . ASP B  1 299 ? 45.96170 16.07355  -55.45113 1.000 14.12306 ? 299 ASP B CB  1 
ATOM   6495 C  CG  . ASP B  1 299 ? 47.42566 16.25580  -55.79855 1.000 16.30649 ? 299 ASP B CG  1 
ATOM   6496 O  OD1 . ASP B  1 299 ? 48.25087 15.39433  -55.42691 1.000 21.16162 ? 299 ASP B OD1 1 
ATOM   6497 O  OD2 . ASP B  1 299 ? 47.74963 17.27126  -56.44972 1.000 16.96283 ? 299 ASP B OD2 1 
ATOM   6498 N  N   . ILE B  1 300 ? 47.04447 14.03537  -52.70653 1.000 15.71124 ? 300 ILE B N   1 
ATOM   6499 C  CA  . ILE B  1 300 ? 47.51922 14.00840  -51.32907 1.000 17.50412 ? 300 ILE B CA  1 
ATOM   6500 C  C   . ILE B  1 300 ? 49.01648 13.73009  -51.29469 1.000 15.41775 ? 300 ILE B C   1 
ATOM   6501 O  O   . ILE B  1 300 ? 49.56749 13.05655  -52.17086 1.000 15.71040 ? 300 ILE B O   1 
ATOM   6502 C  CB  . ILE B  1 300 ? 46.75223 12.96280  -50.48627 1.000 14.95611 ? 300 ILE B CB  1 
ATOM   6503 C  CG1 . ILE B  1 300 ? 46.90655 11.56960  -51.08831 1.000 17.38595 ? 300 ILE B CG1 1 
ATOM   6504 C  CG2 . ILE B  1 300 ? 45.27824 13.32102  -50.39126 1.000 17.19440 ? 300 ILE B CG2 1 
ATOM   6505 C  CD1 . ILE B  1 300 ? 47.79398 10.66246  -50.28169 1.000 23.11485 ? 300 ILE B CD1 1 
ATOM   6506 N  N   . ILE B  1 301 ? 49.67389 14.26084  -50.26512 1.000 19.64702 ? 301 ILE B N   1 
ATOM   6507 C  CA  . ILE B  1 301 ? 51.09306 14.03798  -50.00903 1.000 14.38184 ? 301 ILE B CA  1 
ATOM   6508 C  C   . ILE B  1 301 ? 51.21924 13.24234  -48.71704 1.000 16.70883 ? 301 ILE B C   1 
ATOM   6509 O  O   . ILE B  1 301 ? 50.57501 13.57238  -47.71365 1.000 15.71730 ? 301 ILE B O   1 
ATOM   6510 C  CB  . ILE B  1 301 ? 51.86713 15.36454  -49.90604 1.000 18.72111 ? 301 ILE B CB  1 
ATOM   6511 C  CG1 . ILE B  1 301 ? 51.61275 16.24322  -51.13214 1.000 15.97706 ? 301 ILE B CG1 1 
ATOM   6512 C  CG2 . ILE B  1 301 ? 53.35935 15.10146  -49.73914 1.000 10.85523 ? 301 ILE B CG2 1 
ATOM   6513 C  CD1 . ILE B  1 301 ? 52.32521 15.77849  -52.37385 1.000 14.32726 ? 301 ILE B CD1 1 
ATOM   6514 N  N   . VAL B  1 302 ? 52.04667 12.19988  -48.73826 1.000 17.36529 ? 302 VAL B N   1 
ATOM   6515 C  CA  . VAL B  1 302 ? 52.28743 11.35503  -47.57403 1.000 15.02085 ? 302 VAL B CA  1 
ATOM   6516 C  C   . VAL B  1 302 ? 53.78014 11.35410  -47.27760 1.000 18.97399 ? 302 VAL B C   1 
ATOM   6517 O  O   . VAL B  1 302 ? 54.59799 11.13686  -48.17934 1.000 19.53766 ? 302 VAL B O   1 
ATOM   6518 C  CB  . VAL B  1 302 ? 51.77208 9.92033   -47.79030 1.000 16.86035 ? 302 VAL B CB  1 
ATOM   6519 C  CG1 . VAL B  1 302 ? 52.21757 9.02693   -46.65225 1.000 17.26458 ? 302 VAL B CG1 1 
ATOM   6520 C  CG2 . VAL B  1 302 ? 50.26366 9.91391   -47.88725 1.000 12.93013 ? 302 VAL B CG2 1 
ATOM   6521 N  N   . ASP B  1 303 ? 54.12987 11.59151  -46.01496 1.000 22.00641 ? 303 ASP B N   1 
ATOM   6522 C  CA  . ASP B  1 303 ? 55.51763 11.63549  -45.56872 1.000 18.37358 ? 303 ASP B CA  1 
ATOM   6523 C  C   . ASP B  1 303 ? 55.86020 10.30317  -44.90881 1.000 22.03565 ? 303 ASP B C   1 
ATOM   6524 O  O   . ASP B  1 303 ? 55.42724 10.03026  -43.78399 1.000 23.76301 ? 303 ASP B O   1 
ATOM   6525 C  CB  . ASP B  1 303 ? 55.73278 12.80170  -44.60606 1.000 17.16704 ? 303 ASP B CB  1 
ATOM   6526 C  CG  . ASP B  1 303 ? 57.19551 13.02542  -44.27257 1.000 20.89425 ? 303 ASP B CG  1 
ATOM   6527 O  OD1 . ASP B  1 303 ? 58.05312 12.30174  -44.81841 1.000 24.62929 ? 303 ASP B OD1 1 
ATOM   6528 O  OD2 . ASP B  1 303 ? 57.48833 13.93041  -43.46355 1.000 25.97628 ? 303 ASP B OD2 1 
ATOM   6529 N  N   . PHE B  1 304 ? 56.63709 9.47696   -45.60906 1.000 21.53729 ? 304 PHE B N   1 
ATOM   6530 C  CA  . PHE B  1 304 ? 57.09393 8.19450   -45.09005 1.000 23.75765 ? 304 PHE B CA  1 
ATOM   6531 C  C   . PHE B  1 304 ? 58.47977 8.27294   -44.46241 1.000 25.78828 ? 304 PHE B C   1 
ATOM   6532 O  O   . PHE B  1 304 ? 59.06191 7.23092   -44.14624 1.000 22.43045 ? 304 PHE B O   1 
ATOM   6533 C  CB  . PHE B  1 304 ? 57.09996 7.13984   -46.19916 1.000 17.83765 ? 304 PHE B CB  1 
ATOM   6534 C  CG  . PHE B  1 304 ? 55.73329 6.67992   -46.61502 1.000 20.38223 ? 304 PHE B CG  1 
ATOM   6535 C  CD1 . PHE B  1 304 ? 54.90271 6.02933   -45.71682 1.000 25.18802 ? 304 PHE B CD1 1 
ATOM   6536 C  CD2 . PHE B  1 304 ? 55.28832 6.87505   -47.91175 1.000 13.95562 ? 304 PHE B CD2 1 
ATOM   6537 C  CE1 . PHE B  1 304 ? 53.64622 5.59504   -46.10050 1.000 21.76917 ? 304 PHE B CE1 1 
ATOM   6538 C  CE2 . PHE B  1 304 ? 54.03450 6.44239   -48.30280 1.000 20.81064 ? 304 PHE B CE2 1 
ATOM   6539 C  CZ  . PHE B  1 304 ? 53.21300 5.80005   -47.39628 1.000 26.64731 ? 304 PHE B CZ  1 
ATOM   6540 N  N   . SER B  1 305 ? 59.01651 9.48148   -44.26912 1.000 26.95900 ? 305 SER B N   1 
ATOM   6541 C  CA  . SER B  1 305 ? 60.40072 9.62077   -43.82375 1.000 29.72286 ? 305 SER B CA  1 
ATOM   6542 C  C   . SER B  1 305 ? 60.63715 8.98004   -42.46075 1.000 33.03925 ? 305 SER B C   1 
ATOM   6543 O  O   . SER B  1 305 ? 61.74197 8.49652   -42.18869 1.000 38.96158 ? 305 SER B O   1 
ATOM   6544 C  CB  . SER B  1 305 ? 60.79296 11.09709  -43.78771 1.000 25.42013 ? 305 SER B CB  1 
ATOM   6545 O  OG  . SER B  1 305 ? 59.91915 11.83471  -42.95274 1.000 21.36451 ? 305 SER B OG  1 
ATOM   6546 N  N   . ARG B  1 306 ? 59.62516 8.96294   -41.59315 1.000 32.02517 ? 306 ARG B N   1 
ATOM   6547 C  CA  . ARG B  1 306 ? 59.74683 8.35780   -40.27295 1.000 29.55153 ? 306 ARG B CA  1 
ATOM   6548 C  C   . ARG B  1 306 ? 59.17209 6.94682   -40.22521 1.000 29.49751 ? 306 ARG B C   1 
ATOM   6549 O  O   . ARG B  1 306 ? 58.78552 6.46997   -39.15308 1.000 31.65519 ? 306 ARG B O   1 
ATOM   6550 C  CB  . ARG B  1 306 ? 59.07960 9.23516   -39.21272 1.000 27.33393 ? 306 ARG B CB  1 
ATOM   6551 C  CG  . ARG B  1 306 ? 59.62688 10.66454  -39.09671 1.000 35.87482 ? 306 ARG B CG  1 
ATOM   6552 C  CD  . ARG B  1 306 ? 61.15576 10.72223  -39.05268 1.000 50.94030 ? 306 ARG B CD  1 
ATOM   6553 N  NE  . ARG B  1 306 ? 61.75017 9.63656   -38.28004 1.000 61.63733 ? 306 ARG B NE  1 
ATOM   6554 C  CZ  . ARG B  1 306 ? 63.05313 9.40590   -38.19284 1.000 57.35653 ? 306 ARG B CZ  1 
ATOM   6555 N  NH1 . ARG B  1 306 ? 63.93673 10.21033  -38.76123 1.000 53.66441 ? 306 ARG B NH1 1 
ATOM   6556 N  NH2 . ARG B  1 306 ? 63.48000 8.33763   -37.52447 1.000 49.43675 ? 306 ARG B NH2 1 
ATOM   6557 N  N   . ALA B  1 307 ? 59.11461 6.26346   -41.36972 1.000 30.28533 ? 307 ALA B N   1 
ATOM   6558 C  CA  . ALA B  1 307 ? 58.56583 4.91457   -41.43211 1.000 26.64213 ? 307 ALA B CA  1 
ATOM   6559 C  C   . ALA B  1 307 ? 59.52796 3.93527   -42.09505 1.000 25.35420 ? 307 ALA B C   1 
ATOM   6560 O  O   . ALA B  1 307 ? 59.08720 2.91268   -42.62668 1.000 28.69576 ? 307 ALA B O   1 
ATOM   6561 C  CB  . ALA B  1 307 ? 57.22239 4.91244   -42.16525 1.000 19.84159 ? 307 ALA B CB  1 
ATOM   6562 N  N   . GLU B  1 308 ? 60.82836 4.22256   -42.07019 1.000 27.52687 ? 308 GLU B N   1 
ATOM   6563 C  CA  . GLU B  1 308 ? 61.81012 3.34923   -42.70256 1.000 24.16084 ? 308 GLU B CA  1 
ATOM   6564 C  C   . GLU B  1 308 ? 61.77115 1.96160   -42.07545 1.000 27.12614 ? 308 GLU B C   1 
ATOM   6565 O  O   . GLU B  1 308 ? 61.93016 1.81306   -40.85981 1.000 28.57175 ? 308 GLU B O   1 
ATOM   6566 C  CB  . GLU B  1 308 ? 63.20633 3.95605   -42.57657 1.000 29.47816 ? 308 GLU B CB  1 
ATOM   6567 C  CG  . GLU B  1 308 ? 64.29713 3.16316   -43.27528 1.000 39.65726 ? 308 GLU B CG  1 
ATOM   6568 C  CD  . GLU B  1 308 ? 65.62630 3.89356   -43.28569 1.000 49.23079 ? 308 GLU B CD  1 
ATOM   6569 O  OE1 . GLU B  1 308 ? 65.75156 4.90962   -42.56899 1.000 44.07641 ? 308 GLU B OE1 1 
ATOM   6570 O  OE2 . GLU B  1 308 ? 66.54294 3.45577   -44.01359 1.000 46.61183 ? 308 GLU B OE2 1 
ATOM   6571 N  N   . GLY B  1 309 ? 61.55178 0.94551   -42.90953 1.000 25.47824 ? 309 GLY B N   1 
ATOM   6572 C  CA  . GLY B  1 309 ? 61.42868 -0.41827  -42.44813 1.000 19.99837 ? 309 GLY B CA  1 
ATOM   6573 C  C   . GLY B  1 309 ? 60.03231 -0.83029  -42.03706 1.000 28.30475 ? 309 GLY B C   1 
ATOM   6574 O  O   . GLY B  1 309 ? 59.80321 -2.02237  -41.79234 1.000 29.80060 ? 309 GLY B O   1 
ATOM   6575 N  N   . LYS B  1 310 ? 59.09431 0.10937   -41.95340 1.000 24.27976 ? 310 LYS B N   1 
ATOM   6576 C  CA  . LYS B  1 310 ? 57.73286 -0.21262  -41.56171 1.000 23.88453 ? 310 LYS B CA  1 
ATOM   6577 C  C   . LYS B  1 310 ? 56.93119 -0.71227  -42.76065 1.000 22.29510 ? 310 LYS B C   1 
ATOM   6578 O  O   . LYS B  1 310 ? 57.24605 -0.42734  -43.91906 1.000 21.14630 ? 310 LYS B O   1 
ATOM   6579 C  CB  . LYS B  1 310 ? 57.04135 1.00732   -40.95061 1.000 25.03081 ? 310 LYS B CB  1 
ATOM   6580 C  CG  . LYS B  1 310 ? 57.77773 1.63957   -39.77924 1.000 29.50106 ? 310 LYS B CG  1 
ATOM   6581 C  CD  . LYS B  1 310 ? 56.94591 1.57277   -38.50665 1.000 33.62601 ? 310 LYS B CD  1 
ATOM   6582 C  CE  . LYS B  1 310 ? 57.47176 2.52336   -37.44248 1.000 33.92394 ? 310 LYS B CE  1 
ATOM   6583 N  NZ  . LYS B  1 310 ? 57.27216 3.95074   -37.82228 1.000 42.60389 ? 310 LYS B NZ  1 
ATOM   6584 N  N   . THR B  1 311 ? 55.87841 -1.46893  -42.46365 1.000 23.02398 ? 311 THR B N   1 
ATOM   6585 C  CA  . THR B  1 311 ? 54.93674 -1.95934  -43.46448 1.000 23.62014 ? 311 THR B CA  1 
ATOM   6586 C  C   . THR B  1 311 ? 53.61575 -1.22700  -43.25711 1.000 25.51693 ? 311 THR B C   1 
ATOM   6587 O  O   . THR B  1 311 ? 52.88119 -1.51720  -42.30682 1.000 26.87865 ? 311 THR B O   1 
ATOM   6588 C  CB  . THR B  1 311 ? 54.75693 -3.47278  -43.35448 1.000 24.71468 ? 311 THR B CB  1 
ATOM   6589 O  OG1 . THR B  1 311 ? 55.99868 -4.12584  -43.64743 1.000 30.88241 ? 311 THR B OG1 1 
ATOM   6590 C  CG2 . THR B  1 311 ? 53.69626 -3.95860  -44.32863 1.000 23.39750 ? 311 THR B CG2 1 
ATOM   6591 N  N   . VAL B  1 312 ? 53.31915 -0.27829  -44.14047 1.000 24.25366 ? 312 VAL B N   1 
ATOM   6592 C  CA  . VAL B  1 312 ? 52.15182 0.58712   -44.01143 1.000 23.77628 ? 312 VAL B CA  1 
ATOM   6593 C  C   . VAL B  1 312 ? 51.09488 0.12461   -45.00439 1.000 23.27314 ? 312 VAL B C   1 
ATOM   6594 O  O   . VAL B  1 312 ? 51.32036 0.14855   -46.21989 1.000 29.61433 ? 312 VAL B O   1 
ATOM   6595 C  CB  . VAL B  1 312 ? 52.51964 2.06002   -44.24238 1.000 20.58925 ? 312 VAL B CB  1 
ATOM   6596 C  CG1 . VAL B  1 312 ? 51.30170 2.94525   -44.04552 1.000 24.77204 ? 312 VAL B CG1 1 
ATOM   6597 C  CG2 . VAL B  1 312 ? 53.64780 2.47608   -43.30625 1.000 20.77074 ? 312 VAL B CG2 1 
ATOM   6598 N  N   . THR B  1 313 ? 49.94099 -0.28968  -44.49193 1.000 22.63722 ? 313 THR B N   1 
ATOM   6599 C  CA  . THR B  1 313 ? 48.84546 -0.77532  -45.31885 1.000 19.78820 ? 313 THR B CA  1 
ATOM   6600 C  C   . THR B  1 313 ? 47.77599 0.30155   -45.44853 1.000 21.05030 ? 313 THR B C   1 
ATOM   6601 O  O   . THR B  1 313 ? 47.29508 0.83194   -44.44133 1.000 19.65509 ? 313 THR B O   1 
ATOM   6602 C  CB  . THR B  1 313 ? 48.23521 -2.04648  -44.72663 1.000 18.40842 ? 313 THR B CB  1 
ATOM   6603 O  OG1 . THR B  1 313 ? 49.26698 -3.01503  -44.50335 1.000 29.38816 ? 313 THR B OG1 1 
ATOM   6604 C  CG2 . THR B  1 313 ? 47.20056 -2.63075  -45.67812 1.000 20.85589 ? 313 THR B CG2 1 
ATOM   6605 N  N   . LEU B  1 314 ? 47.41190 0.62441   -46.68643 1.000 17.03286 ? 314 LEU B N   1 
ATOM   6606 C  CA  . LEU B  1 314 ? 46.29394 1.52368   -46.94116 1.000 16.27670 ? 314 LEU B CA  1 
ATOM   6607 C  C   . LEU B  1 314 ? 44.99403 0.75335   -46.74729 1.000 15.68353 ? 314 LEU B C   1 
ATOM   6608 O  O   . LEU B  1 314 ? 44.73079 -0.22043  -47.46183 1.000 15.75296 ? 314 LEU B O   1 
ATOM   6609 C  CB  . LEU B  1 314 ? 46.38119 2.10495   -48.35064 1.000 16.44066 ? 314 LEU B CB  1 
ATOM   6610 C  CG  . LEU B  1 314 ? 45.28219 3.08959   -48.75588 1.000 19.55558 ? 314 LEU B CG  1 
ATOM   6611 C  CD1 . LEU B  1 314 ? 45.20384 4.24467   -47.77101 1.000 19.70799 ? 314 LEU B CD1 1 
ATOM   6612 C  CD2 . LEU B  1 314 ? 45.52011 3.60325   -50.16722 1.000 18.56423 ? 314 LEU B CD2 1 
ATOM   6613 N  N   . LYS B  1 315 ? 44.18861 1.18024   -45.78143 1.000 15.38352 ? 315 LYS B N   1 
ATOM   6614 C  CA  . LYS B  1 315 ? 43.00163 0.44718   -45.36993 1.000 16.87057 ? 315 LYS B CA  1 
ATOM   6615 C  C   . LYS B  1 315 ? 41.73492 1.17298   -45.80741 1.000 20.87312 ? 315 LYS B C   1 
ATOM   6616 O  O   . LYS B  1 315 ? 41.75470 2.34246   -46.20011 1.000 17.21283 ? 315 LYS B O   1 
ATOM   6617 C  CB  . LYS B  1 315 ? 42.99616 0.23811   -43.85116 1.000 20.01369 ? 315 LYS B CB  1 
ATOM   6618 C  CG  . LYS B  1 315 ? 44.22181 -0.48473  -43.31685 1.000 21.37787 ? 315 LYS B CG  1 
ATOM   6619 C  CD  . LYS B  1 315 ? 44.23294 -1.94738  -43.72951 1.000 21.71137 ? 315 LYS B CD  1 
ATOM   6620 C  CE  . LYS B  1 315 ? 43.14246 -2.73376  -43.01813 1.000 22.48470 ? 315 LYS B CE  1 
ATOM   6621 N  NZ  . LYS B  1 315 ? 43.31567 -2.71152  -41.54062 1.000 24.30126 ? 315 LYS B NZ  1 
ATOM   6622 N  N   . ASN B  1 316 ? 40.62092 0.44577   -45.73446 1.000 23.33266 ? 316 ASN B N   1 
ATOM   6623 C  CA  . ASN B  1 316 ? 39.29690 0.96606   -46.04843 1.000 17.94803 ? 316 ASN B CA  1 
ATOM   6624 C  C   . ASN B  1 316 ? 38.37463 0.65457   -44.88024 1.000 16.09095 ? 316 ASN B C   1 
ATOM   6625 O  O   . ASN B  1 316 ? 38.30136 -0.49437  -44.43602 1.000 17.82093 ? 316 ASN B O   1 
ATOM   6626 C  CB  . ASN B  1 316 ? 38.75251 0.35254   -47.34376 1.000 19.54313 ? 316 ASN B CB  1 
ATOM   6627 C  CG  . ASN B  1 316 ? 37.39162 0.90409   -47.72678 1.000 19.40660 ? 316 ASN B CG  1 
ATOM   6628 O  OD1 . ASN B  1 316 ? 37.07360 2.05852   -47.44117 1.000 17.42622 ? 316 ASN B OD1 1 
ATOM   6629 N  ND2 . ASN B  1 316 ? 36.57735 0.07545   -48.37344 1.000 19.15419 ? 316 ASN B ND2 1 
ATOM   6630 N  N   . ARG B  1 317 ? 37.67237 1.67125   -44.38565 1.000 16.16949 ? 317 ARG B N   1 
ATOM   6631 C  CA  . ARG B  1 317 ? 36.90190 1.52372   -43.15677 1.000 17.11624 ? 317 ARG B CA  1 
ATOM   6632 C  C   . ARG B  1 317 ? 35.50025 0.98126   -43.38687 1.000 19.52728 ? 317 ARG B C   1 
ATOM   6633 O  O   . ARG B  1 317 ? 34.98688 0.23424   -42.54337 1.000 21.16196 ? 317 ARG B O   1 
ATOM   6634 C  CB  . ARG B  1 317 ? 36.82474 2.87098   -42.42836 1.000 17.81129 ? 317 ARG B CB  1 
ATOM   6635 C  CG  . ARG B  1 317 ? 36.04180 2.84291   -41.12496 1.000 18.45282 ? 317 ARG B CG  1 
ATOM   6636 C  CD  . ARG B  1 317 ? 36.36049 4.05235   -40.25432 1.000 25.67614 ? 317 ARG B CD  1 
ATOM   6637 N  NE  . ARG B  1 317 ? 35.47750 4.13963   -39.09577 1.000 42.29303 ? 317 ARG B NE  1 
ATOM   6638 C  CZ  . ARG B  1 317 ? 35.54207 5.08697   -38.16860 1.000 39.82674 ? 317 ARG B CZ  1 
ATOM   6639 N  NH1 . ARG B  1 317 ? 36.45588 6.04287   -38.21835 1.000 39.76023 ? 317 ARG B NH1 1 
ATOM   6640 N  NH2 . ARG B  1 317 ? 34.66626 5.07586   -37.16668 1.000 28.65715 ? 317 ARG B NH2 1 
ATOM   6641 N  N   . ILE B  1 318 ? 34.87557 1.32136   -44.51063 1.000 18.68867 ? 318 ILE B N   1 
ATOM   6642 C  CA  . ILE B  1 318 ? 33.47174 1.01679   -44.73836 1.000 15.23553 ? 318 ILE B CA  1 
ATOM   6643 C  C   . ILE B  1 318 ? 33.33400 0.02402   -45.88278 1.000 16.50729 ? 318 ILE B C   1 
ATOM   6644 O  O   . ILE B  1 318 ? 34.23360 -0.17405  -46.70273 1.000 19.31043 ? 318 ILE B O   1 
ATOM   6645 C  CB  . ILE B  1 318 ? 32.64306 2.28202   -45.02614 1.000 17.46939 ? 318 ILE B CB  1 
ATOM   6646 C  CG1 . ILE B  1 318 ? 33.19692 2.99241   -46.26055 1.000 13.97664 ? 318 ILE B CG1 1 
ATOM   6647 C  CG2 . ILE B  1 318 ? 32.64701 3.19030   -43.81584 1.000 20.05527 ? 318 ILE B CG2 1 
ATOM   6648 C  CD1 . ILE B  1 318 ? 32.45569 4.24387   -46.63172 1.000 15.08285 ? 318 ILE B CD1 1 
ATOM   6649 N  N   . GLY B  1 319 ? 32.16828 -0.59919  -45.92883 1.000 18.47427 ? 319 GLY B N   1 
ATOM   6650 C  CA  . GLY B  1 319 ? 31.84239 -1.61666  -46.90253 1.000 19.10007 ? 319 GLY B CA  1 
ATOM   6651 C  C   . GLY B  1 319 ? 30.91084 -1.11189  -47.98498 1.000 24.18864 ? 319 GLY B C   1 
ATOM   6652 O  O   . GLY B  1 319 ? 31.02383 0.03016   -48.44672 1.000 27.18891 ? 319 GLY B O   1 
ATOM   6653 N  N   . CYS B  1 320 ? 29.98659 -1.97375  -48.39299 1.000 30.56258 ? 320 CYS B N   1 
ATOM   6654 C  CA  . CYS B  1 320 ? 29.10425 -1.70470  -49.52121 1.000 27.64563 ? 320 CYS B CA  1 
ATOM   6655 C  C   . CYS B  1 320 ? 27.88132 -0.86914  -49.15339 1.000 28.27638 ? 320 CYS B C   1 
ATOM   6656 O  O   . CYS B  1 320 ? 27.41901 -0.06771  -49.97378 1.000 30.75024 ? 320 CYS B O   1 
ATOM   6657 C  CB  . CYS B  1 320 ? 28.64898 -3.03051  -50.12138 1.000 39.23976 ? 320 CYS B CB  1 
ATOM   6658 S  SG  . CYS B  1 320 ? 28.15750 -3.01504  -51.83421 1.000 62.39448 ? 320 CYS B SG  1 
ATOM   6659 N  N   . SER B  1 321 ? 27.32617 -1.05847  -47.95643 1.000 34.77624 ? 321 SER B N   1 
ATOM   6660 C  CA  . SER B  1 321 ? 26.20383 -0.25860  -47.48390 1.000 26.05483 ? 321 SER B CA  1 
ATOM   6661 C  C   . SER B  1 321 ? 26.60971 0.67416   -46.35314 1.000 19.14446 ? 321 SER B C   1 
ATOM   6662 O  O   . SER B  1 321 ? 25.76242 1.08013   -45.55306 1.000 21.69832 ? 321 SER B O   1 
ATOM   6663 C  CB  . SER B  1 321 ? 25.05172 -1.15405  -47.02376 1.000 24.29690 ? 321 SER B CB  1 
ATOM   6664 O  OG  . SER B  1 321 ? 24.58556 -2.00046  -48.06000 1.000 33.58043 ? 321 SER B OG  1 
ATOM   6665 N  N   . GLY B  1 322 ? 27.89425 1.00972   -46.26842 1.000 17.40581 ? 322 GLY B N   1 
ATOM   6666 C  CA  . GLY B  1 322 ? 28.39527 1.85633   -45.21156 1.000 18.41326 ? 322 GLY B CA  1 
ATOM   6667 C  C   . GLY B  1 322 ? 28.71914 1.15158   -43.91253 1.000 17.59017 ? 322 GLY B C   1 
ATOM   6668 O  O   . GLY B  1 322 ? 29.15997 1.81454   -42.96487 1.000 16.66488 ? 322 GLY B O   1 
ATOM   6669 N  N   . GLN B  1 323 ? 28.51681 -0.16160  -43.83149 1.000 16.20615 ? 323 GLN B N   1 
ATOM   6670 C  CA  . GLN B  1 323 ? 28.81297 -0.90633  -42.61769 1.000 15.07601 ? 323 GLN B CA  1 
ATOM   6671 C  C   . GLN B  1 323 ? 30.32425 -1.03161  -42.43810 1.000 14.90443 ? 323 GLN B C   1 
ATOM   6672 O  O   . GLN B  1 323 ? 31.11731 -0.61989  -43.28860 1.000 19.10560 ? 323 GLN B O   1 
ATOM   6673 C  CB  . GLN B  1 323 ? 28.15086 -2.28283  -42.66688 1.000 16.65283 ? 323 GLN B CB  1 
ATOM   6674 C  CG  . GLN B  1 323 ? 28.78967 -3.27776  -43.64633 1.000 12.43795 ? 323 GLN B CG  1 
ATOM   6675 C  CD  . GLN B  1 323 ? 28.41304 -3.02698  -45.09906 1.000 21.71737 ? 323 GLN B CD  1 
ATOM   6676 O  OE1 . GLN B  1 323 ? 28.50392 -1.90288  -45.59384 1.000 28.20724 ? 323 GLN B OE1 1 
ATOM   6677 N  NE2 . GLN B  1 323 ? 27.98850 -4.08041  -45.79021 1.000 18.87861 ? 323 GLN B NE2 1 
ATOM   6678 N  N   . ASP B  1 324 ? 30.72837 -1.60903  -41.30919 1.000 13.07004 ? 324 ASP B N   1 
ATOM   6679 C  CA  . ASP B  1 324 ? 32.14240 -1.86827  -41.07739 1.000 17.51867 ? 324 ASP B CA  1 
ATOM   6680 C  C   . ASP B  1 324 ? 32.67186 -2.83720  -42.12416 1.000 17.78456 ? 324 ASP B C   1 
ATOM   6681 O  O   . ASP B  1 324 ? 32.06393 -3.87794  -42.39110 1.000 19.53165 ? 324 ASP B O   1 
ATOM   6682 C  CB  . ASP B  1 324 ? 32.36105 -2.42621  -39.67096 1.000 17.72774 ? 324 ASP B CB  1 
ATOM   6683 C  CG  . ASP B  1 324 ? 32.53012 -1.33333  -38.63231 1.000 21.12511 ? 324 ASP B CG  1 
ATOM   6684 O  OD1 . ASP B  1 324 ? 32.67583 -0.15701  -39.02734 1.000 21.78461 ? 324 ASP B OD1 1 
ATOM   6685 O  OD2 . ASP B  1 324 ? 32.51741 -1.64670  -37.42343 1.000 23.23314 ? 324 ASP B OD2 1 
ATOM   6686 N  N   . ALA B  1 325 ? 33.80430 -2.48358  -42.72317 1.000 21.30065 ? 325 ALA B N   1 
ATOM   6687 C  CA  . ALA B  1 325 ? 34.35949 -3.28230  -43.80440 1.000 18.52513 ? 325 ALA B CA  1 
ATOM   6688 C  C   . ALA B  1 325 ? 34.81970 -4.64167  -43.29562 1.000 21.05730 ? 325 ALA B C   1 
ATOM   6689 O  O   . ALA B  1 325 ? 35.33482 -4.76846  -42.18088 1.000 22.11979 ? 325 ALA B O   1 
ATOM   6690 C  CB  . ALA B  1 325 ? 35.52599 -2.54680  -44.46162 1.000 15.65484 ? 325 ALA B CB  1 
ATOM   6691 N  N   . ASP B  1 326 ? 34.61197 -5.66082  -44.11482 1.000 22.09182 ? 326 ASP B N   1 
ATOM   6692 C  CA  . ASP B  1 326 ? 35.17609 -6.97210  -43.83167 1.000 27.58740 ? 326 ASP B CA  1 
ATOM   6693 C  C   . ASP B  1 326 ? 36.69176 -6.89198  -43.96658 1.000 24.73681 ? 326 ASP B C   1 
ATOM   6694 O  O   . ASP B  1 326 ? 37.18856 -6.32002  -44.94301 1.000 31.00742 ? 326 ASP B O   1 
ATOM   6695 C  CB  . ASP B  1 326 ? 34.60017 -8.00873  -44.80055 1.000 26.96954 ? 326 ASP B CB  1 
ATOM   6696 C  CG  . ASP B  1 326 ? 35.04352 -9.43299  -44.48864 1.000 31.83000 ? 326 ASP B CG  1 
ATOM   6697 O  OD1 . ASP B  1 326 ? 35.69078 -9.66245  -43.44905 1.000 39.12827 ? 326 ASP B OD1 1 
ATOM   6698 O  OD2 . ASP B  1 326 ? 34.73508 -10.33566 -45.29479 1.000 34.59366 ? 326 ASP B OD2 1 
ATOM   6699 N  N   . PRO B  1 327 ? 37.46105 -7.42449  -43.01350 1.000 26.27995 ? 327 PRO B N   1 
ATOM   6700 C  CA  . PRO B  1 327 ? 38.92147 -7.47614  -43.19349 1.000 26.64564 ? 327 PRO B CA  1 
ATOM   6701 C  C   . PRO B  1 327 ? 39.38228 -8.21271  -44.45023 1.000 38.52340 ? 327 PRO B C   1 
ATOM   6702 O  O   . PRO B  1 327 ? 40.31865 -9.01663  -44.39745 1.000 34.67795 ? 327 PRO B O   1 
ATOM   6703 C  CB  . PRO B  1 327 ? 39.39376 -8.18800  -41.92163 1.000 26.51286 ? 327 PRO B CB  1 
ATOM   6704 C  CG  . PRO B  1 327 ? 38.39358 -7.76925  -40.89069 1.000 16.09660 ? 327 PRO B CG  1 
ATOM   6705 C  CD  . PRO B  1 327 ? 37.07029 -7.67216  -41.61235 1.000 19.01811 ? 327 PRO B CD  1 
ATOM   6706 N  N   . THR B  1 329 ? 38.72453 -7.94714  -45.58259 1.000 45.86040 ? 328 THR B N   1 
ATOM   6707 C  CA  . THR B  1 329 ? 39.21844 -8.30980  -46.90604 1.000 29.69677 ? 328 THR B CA  1 
ATOM   6708 C  C   . THR B  1 329 ? 39.07412 -7.10452  -47.83022 1.000 25.65927 ? 328 THR B C   1 
ATOM   6709 O  O   . THR B  1 329 ? 40.05515 -6.66546  -48.43871 1.000 27.07998 ? 328 THR B O   1 
ATOM   6710 C  CB  . THR B  1 329 ? 38.48607 -9.53408  -47.47298 1.000 36.42415 ? 328 THR B CB  1 
ATOM   6711 O  OG1 . THR B  1 329 ? 38.79806 -9.67747  -48.86422 1.000 43.16758 ? 328 THR B OG1 1 
ATOM   6712 C  CG2 . THR B  1 329 ? 36.97837 -9.41528  -47.30896 1.000 28.69542 ? 328 THR B CG2 1 
ATOM   6713 N  N   . ASP B  1 330 ? 37.86380 -6.54893  -47.92924 1.000 28.07828 ? 329 ASP B N   1 
ATOM   6714 C  CA  . ASP B  1 330 ? 37.66245 -5.28099  -48.61809 1.000 22.01038 ? 329 ASP B CA  1 
ATOM   6715 C  C   . ASP B  1 330 ? 38.03743 -4.09105  -47.74800 1.000 18.12543 ? 329 ASP B C   1 
ATOM   6716 O  O   . ASP B  1 330 ? 37.91761 -2.94666  -48.19863 1.000 21.94010 ? 329 ASP B O   1 
ATOM   6717 C  CB  . ASP B  1 330 ? 36.21094 -5.14980  -49.09862 1.000 19.43192 ? 329 ASP B CB  1 
ATOM   6718 C  CG  . ASP B  1 330 ? 35.22644 -4.92547  -47.96245 1.000 20.77195 ? 329 ASP B CG  1 
ATOM   6719 O  OD1 . ASP B  1 330 ? 35.49035 -5.38451  -46.83282 1.000 18.52407 ? 329 ASP B OD1 1 
ATOM   6720 O  OD2 . ASP B  1 330 ? 34.17518 -4.29364  -48.20579 1.000 17.60189 ? 329 ASP B OD2 1 
ATOM   6721 N  N   . ALA B  1 331 ? 38.47809 -4.33728  -46.51561 1.000 21.74098 ? 330 ALA B N   1 
ATOM   6722 C  CA  . ALA B  1 331 ? 39.08077 -3.30900  -45.68129 1.000 22.45504 ? 330 ALA B CA  1 
ATOM   6723 C  C   . ALA B  1 331 ? 40.52293 -3.01787  -46.06877 1.000 20.39036 ? 330 ALA B C   1 
ATOM   6724 O  O   . ALA B  1 331 ? 41.14145 -2.13237  -45.47057 1.000 21.52728 ? 330 ALA B O   1 
ATOM   6725 C  CB  . ALA B  1 331 ? 39.01608 -3.71841  -44.20716 1.000 13.25641 ? 330 ALA B CB  1 
ATOM   6726 N  N   . ASN B  1 332 ? 41.06755 -3.73729  -47.04553 1.000 18.71070 ? 331 ASN B N   1 
ATOM   6727 C  CA  . ASN B  1 332 ? 42.43746 -3.55556  -47.50139 1.000 17.47157 ? 331 ASN B CA  1 
ATOM   6728 C  C   . ASN B  1 332 ? 42.43146 -2.99804  -48.91666 1.000 18.52405 ? 331 ASN B C   1 
ATOM   6729 O  O   . ASN B  1 332 ? 41.69586 -3.48896  -49.78060 1.000 16.87323 ? 331 ASN B O   1 
ATOM   6730 C  CB  . ASN B  1 332 ? 43.20873 -4.87610  -47.46476 1.000 18.86870 ? 331 ASN B CB  1 
ATOM   6731 C  CG  . ASN B  1 332 ? 43.10642 -5.57123  -46.12766 1.000 16.30190 ? 331 ASN B CG  1 
ATOM   6732 O  OD1 . ASN B  1 332 ? 43.85551 -5.26933  -45.19938 1.000 18.99163 ? 331 ASN B OD1 1 
ATOM   6733 N  ND2 . ASN B  1 332 ? 42.17576 -6.51161  -46.02096 1.000 19.29568 ? 331 ASN B ND2 1 
ATOM   6734 N  N   . ILE B  1 333 ? 43.25173 -1.97654  -49.14836 1.000 15.15667 ? 332 ILE B N   1 
ATOM   6735 C  CA  . ILE B  1 333 ? 43.41383 -1.40504  -50.47865 1.000 15.39392 ? 332 ILE B CA  1 
ATOM   6736 C  C   . ILE B  1 333 ? 44.71498 -1.93080  -51.06710 1.000 18.51632 ? 332 ILE B C   1 
ATOM   6737 O  O   . ILE B  1 333 ? 44.70631 -2.70777  -52.02847 1.000 18.26360 ? 332 ILE B O   1 
ATOM   6738 C  CB  . ILE B  1 333 ? 43.39601 0.13312   -50.43295 1.000 14.17068 ? 332 ILE B CB  1 
ATOM   6739 C  CG1 . ILE B  1 333 ? 42.09282 0.62868   -49.80258 1.000 12.93971 ? 332 ILE B CG1 1 
ATOM   6740 C  CG2 . ILE B  1 333 ? 43.56769 0.70935   -51.82505 1.000 12.51219 ? 332 ILE B CG2 1 
ATOM   6741 C  CD1 . ILE B  1 333 ? 40.85123 0.22869   -50.57073 1.000 12.43770 ? 332 ILE B CD1 1 
ATOM   6742 N  N   . MET B  1 334 ? 45.83912 -1.51792  -50.48766 1.000 19.47542 ? 333 MET B N   1 
ATOM   6743 C  CA  . MET B  1 334 ? 47.14490 -2.01963  -50.89256 1.000 17.61815 ? 333 MET B CA  1 
ATOM   6744 C  C   . MET B  1 334 ? 48.12065 -1.79766  -49.74526 1.000 21.12294 ? 333 MET B C   1 
ATOM   6745 O  O   . MET B  1 334 ? 47.80567 -1.13829  -48.75172 1.000 18.98718 ? 333 MET B O   1 
ATOM   6746 C  CB  . MET B  1 334 ? 47.63744 -1.34693  -52.17836 1.000 17.19401 ? 333 MET B CB  1 
ATOM   6747 C  CG  . MET B  1 334 ? 48.00001 0.11636   -52.02093 1.000 17.63267 ? 333 MET B CG  1 
ATOM   6748 S  SD  . MET B  1 334 ? 48.83661 0.75672   -53.48023 1.000 23.59360 ? 333 MET B SD  1 
ATOM   6749 C  CE  . MET B  1 334 ? 50.23351 -0.35971  -53.57149 1.000 20.61342 ? 333 MET B CE  1 
ATOM   6750 N  N   . GLN B  1 335 ? 49.31800 -2.35444  -49.90019 1.000 18.33207 ? 334 GLN B N   1 
ATOM   6751 C  CA  . GLN B  1 335 ? 50.32605 -2.36702  -48.85019 1.000 19.68351 ? 334 GLN B CA  1 
ATOM   6752 C  C   . GLN B  1 335 ? 51.58206 -1.65676  -49.33277 1.000 25.33575 ? 334 GLN B C   1 
ATOM   6753 O  O   . GLN B  1 335 ? 52.11498 -1.98412  -50.39788 1.000 24.34857 ? 334 GLN B O   1 
ATOM   6754 C  CB  . GLN B  1 335 ? 50.64918 -3.80547  -48.43553 1.000 24.60629 ? 334 GLN B CB  1 
ATOM   6755 C  CG  . GLN B  1 335 ? 51.82294 -3.94386  -47.48525 1.000 30.72536 ? 334 GLN B CG  1 
ATOM   6756 C  CD  . GLN B  1 335 ? 52.02741 -5.37539  -47.02869 1.000 31.88855 ? 334 GLN B CD  1 
ATOM   6757 O  OE1 . GLN B  1 335 ? 53.00151 -6.02760  -47.40548 1.000 29.73678 ? 334 GLN B OE1 1 
ATOM   6758 N  NE2 . GLN B  1 335 ? 51.10673 -5.87145  -46.21072 1.000 30.71145 ? 334 GLN B NE2 1 
ATOM   6759 N  N   . PHE B  1 336 ? 52.05107 -0.68865  -48.55034 1.000 19.75196 ? 335 PHE B N   1 
ATOM   6760 C  CA  . PHE B  1 336 ? 53.28609 0.02777   -48.84142 1.000 20.12021 ? 335 PHE B CA  1 
ATOM   6761 C  C   . PHE B  1 336 ? 54.38147 -0.47727  -47.91074 1.000 22.34353 ? 335 PHE B C   1 
ATOM   6762 O  O   . PHE B  1 336 ? 54.23146 -0.42804  -46.68508 1.000 26.64050 ? 335 PHE B O   1 
ATOM   6763 C  CB  . PHE B  1 336 ? 53.10071 1.53633   -48.68124 1.000 21.33820 ? 335 PHE B CB  1 
ATOM   6764 C  CG  . PHE B  1 336 ? 52.18096 2.14836   -49.69911 1.000 26.84488 ? 335 PHE B CG  1 
ATOM   6765 C  CD1 . PHE B  1 336 ? 52.58379 2.29466   -51.01595 1.000 21.60081 ? 335 PHE B CD1 1 
ATOM   6766 C  CD2 . PHE B  1 336 ? 50.91844 2.58858   -49.33697 1.000 22.22554 ? 335 PHE B CD2 1 
ATOM   6767 C  CE1 . PHE B  1 336 ? 51.74422 2.86350   -51.95342 1.000 19.18146 ? 335 PHE B CE1 1 
ATOM   6768 C  CE2 . PHE B  1 336 ? 50.07388 3.15599   -50.27019 1.000 21.11153 ? 335 PHE B CE2 1 
ATOM   6769 C  CZ  . PHE B  1 336 ? 50.48778 3.29405   -51.58037 1.000 22.02884 ? 335 PHE B CZ  1 
ATOM   6770 N  N   . ARG B  1 337 ? 55.47577 -0.96117  -48.49247 1.000 20.68976 ? 336 ARG B N   1 
ATOM   6771 C  CA  . ARG B  1 337 ? 56.62233 -1.46362  -47.74272 1.000 17.77550 ? 336 ARG B CA  1 
ATOM   6772 C  C   . ARG B  1 337 ? 57.76601 -0.47164  -47.90738 1.000 19.95580 ? 336 ARG B C   1 
ATOM   6773 O  O   . ARG B  1 337 ? 58.33754 -0.34955  -48.99581 1.000 21.38875 ? 336 ARG B O   1 
ATOM   6774 C  CB  . ARG B  1 337 ? 57.02188 -2.85468  -48.22738 1.000 17.50440 ? 336 ARG B CB  1 
ATOM   6775 C  CG  . ARG B  1 337 ? 55.90978 -3.87958  -48.11830 1.000 21.55577 ? 336 ARG B CG  1 
ATOM   6776 C  CD  . ARG B  1 337 ? 56.21819 -5.12055  -48.93555 1.000 24.22422 ? 336 ARG B CD  1 
ATOM   6777 N  NE  . ARG B  1 337 ? 55.08211 -6.03295  -48.97391 1.000 24.83126 ? 336 ARG B NE  1 
ATOM   6778 C  CZ  . ARG B  1 337 ? 55.02466 -7.12811  -49.71868 1.000 26.90246 ? 336 ARG B CZ  1 
ATOM   6779 N  NH1 . ARG B  1 337 ? 56.02686 -7.48123  -50.50782 1.000 20.10146 ? 336 ARG B NH1 1 
ATOM   6780 N  NH2 . ARG B  1 337 ? 53.93293 -7.88654  -49.67274 1.000 32.60541 ? 336 ARG B NH2 1 
ATOM   6781 N  N   . ILE B  1 338 ? 58.09919 0.23339   -46.82897 1.000 19.42099 ? 337 ILE B N   1 
ATOM   6782 C  CA  . ILE B  1 338 ? 59.13362 1.26065   -46.87445 1.000 25.23920 ? 337 ILE B CA  1 
ATOM   6783 C  C   . ILE B  1 338 ? 60.50097 0.59631   -46.76714 1.000 26.02286 ? 337 ILE B C   1 
ATOM   6784 O  O   . ILE B  1 338 ? 61.22291 0.78757   -45.78171 1.000 17.29451 ? 337 ILE B O   1 
ATOM   6785 C  CB  . ILE B  1 338 ? 58.93043 2.30254   -45.75931 1.000 18.10957 ? 337 ILE B CB  1 
ATOM   6786 C  CG1 . ILE B  1 338 ? 57.43915 2.55390   -45.52616 1.000 17.29825 ? 337 ILE B CG1 1 
ATOM   6787 C  CG2 . ILE B  1 338 ? 59.62809 3.60490   -46.11296 1.000 19.59449 ? 337 ILE B CG2 1 
ATOM   6788 C  CD1 . ILE B  1 338 ? 56.72805 3.18328   -46.70375 1.000 17.93604 ? 337 ILE B CD1 1 
ATOM   6789 N  N   . SER B  1 339 ? 60.86881 -0.18629  -47.78513 1.000 27.47958 ? 338 SER B N   1 
ATOM   6790 C  CA  . SER B  1 339 ? 62.10801 -0.94921  -47.76260 1.000 24.51161 ? 338 SER B CA  1 
ATOM   6791 C  C   . SER B  1 339 ? 63.13995 -0.49510  -48.78503 1.000 31.20559 ? 338 SER B C   1 
ATOM   6792 O  O   . SER B  1 339 ? 64.31759 -0.83337  -48.63175 1.000 30.10956 ? 338 SER B O   1 
ATOM   6793 C  CB  . SER B  1 339 ? 61.81874 -2.44204  -47.98289 1.000 20.56365 ? 338 SER B CB  1 
ATOM   6794 O  OG  . SER B  1 339 ? 61.14701 -2.66027  -49.21163 1.000 23.49823 ? 338 SER B OG  1 
ATOM   6795 N  N   . LYS B  1 340 ? 62.74059 0.24254   -49.81638 1.000 30.38626 ? 339 LYS B N   1 
ATOM   6796 C  CA  . LYS B  1 340 ? 63.71504 0.74865   -50.77742 1.000 32.09716 ? 339 LYS B CA  1 
ATOM   6797 C  C   . LYS B  1 340 ? 64.61398 1.77484   -50.09801 1.000 28.54961 ? 339 LYS B C   1 
ATOM   6798 O  O   . LYS B  1 340 ? 64.11319 2.66271   -49.39794 1.000 26.94876 ? 339 LYS B O   1 
ATOM   6799 C  CB  . LYS B  1 340 ? 63.02585 1.37657   -51.98944 1.000 30.67267 ? 339 LYS B CB  1 
ATOM   6800 C  CG  . LYS B  1 340 ? 62.95204 0.47245   -53.21632 1.000 29.70672 ? 339 LYS B CG  1 
ATOM   6801 C  CD  . LYS B  1 340 ? 62.48027 1.24332   -54.44760 1.000 34.66117 ? 339 LYS B CD  1 
ATOM   6802 C  CE  . LYS B  1 340 ? 63.64135 1.65739   -55.34907 1.000 41.44547 ? 339 LYS B CE  1 
ATOM   6803 N  NZ  . LYS B  1 340 ? 64.09069 0.54875   -56.24460 1.000 39.52721 ? 339 LYS B NZ  1 
ATOM   6804 N  N   . PRO B  1 341 ? 65.93172 1.68572   -50.26479 1.000 37.78959 ? 340 PRO B N   1 
ATOM   6805 C  CA  . PRO B  1 341 ? 66.81453 2.68178   -49.64907 1.000 33.84801 ? 340 PRO B CA  1 
ATOM   6806 C  C   . PRO B  1 341 ? 66.64658 4.03963   -50.31006 1.000 34.16203 ? 340 PRO B C   1 
ATOM   6807 O  O   . PRO B  1 341 ? 66.40626 4.13988   -51.51582 1.000 35.85958 ? 340 PRO B O   1 
ATOM   6808 C  CB  . PRO B  1 341 ? 68.21601 2.10927   -49.88656 1.000 28.30458 ? 340 PRO B CB  1 
ATOM   6809 C  CG  . PRO B  1 341 ? 68.06505 1.26430   -51.10937 1.000 31.78406 ? 340 PRO B CG  1 
ATOM   6810 C  CD  . PRO B  1 341 ? 66.68105 0.67836   -51.03573 1.000 32.09629 ? 340 PRO B CD  1 
ATOM   6811 N  N   . LEU B  1 342 ? 66.76476 5.09039   -49.50089 1.000 30.02136 ? 341 LEU B N   1 
ATOM   6812 C  CA  . LEU B  1 342 ? 66.63460 6.45282   -50.00062 1.000 32.13983 ? 341 LEU B CA  1 
ATOM   6813 C  C   . LEU B  1 342 ? 67.73593 6.75761   -51.00762 1.000 34.53380 ? 341 LEU B C   1 
ATOM   6814 O  O   . LEU B  1 342 ? 68.90600 6.88435   -50.63309 1.000 43.65036 ? 341 LEU B O   1 
ATOM   6815 C  CB  . LEU B  1 342 ? 66.67634 7.45095   -48.84254 1.000 25.23387 ? 341 LEU B CB  1 
ATOM   6816 C  CG  . LEU B  1 342 ? 66.48624 8.92648   -49.19048 1.000 29.11334 ? 341 LEU B CG  1 
ATOM   6817 C  CD1 . LEU B  1 342 ? 65.06561 9.18899   -49.67626 1.000 23.14037 ? 341 LEU B CD1 1 
ATOM   6818 C  CD2 . LEU B  1 342 ? 66.82285 9.80107   -47.99223 1.000 28.80497 ? 341 LEU B CD2 1 
ATOM   6819 N  N   . LYS B  1 343 ? 67.37373 6.86182   -52.28691 1.000 35.55667 ? 342 LYS B N   1 
ATOM   6820 C  CA  . LYS B  1 343 ? 68.33999 7.16402   -53.33696 1.000 39.48391 ? 342 LYS B CA  1 
ATOM   6821 C  C   . LYS B  1 343 ? 69.00123 8.51178   -53.08447 1.000 37.56498 ? 342 LYS B C   1 
ATOM   6822 O  O   . LYS B  1 343 ? 70.10244 8.58093   -52.52865 1.000 44.41687 ? 342 LYS B O   1 
ATOM   6823 C  CB  . LYS B  1 343 ? 67.66721 7.16204   -54.71275 1.000 29.39579 ? 342 LYS B CB  1 
ATOM   6824 C  CG  . LYS B  1 343 ? 67.11138 5.81670   -55.14976 1.000 31.95177 ? 342 LYS B CG  1 
ATOM   6825 C  CD  . LYS B  1 343 ? 66.52073 5.90789   -56.54883 1.000 36.92498 ? 342 LYS B CD  1 
ATOM   6826 C  CE  . LYS B  1 343 ? 65.94948 4.57576   -57.00360 1.000 38.73609 ? 342 LYS B CE  1 
ATOM   6827 N  NZ  . LYS B  1 343 ? 65.40217 4.65425   -58.38734 1.000 34.45156 ? 342 LYS B NZ  1 
ATOM   6828 N  N   . GLN B  1 344 ? 68.33587 9.58352   -53.49288 1.000 30.51486 ? 343 GLN B N   1 
ATOM   6829 C  CA  . GLN B  1 344 ? 68.80336 10.93904  -53.25955 1.000 33.13703 ? 343 GLN B CA  1 
ATOM   6830 C  C   . GLN B  1 344 ? 68.04985 11.55158  -52.08500 1.000 35.05472 ? 343 GLN B C   1 
ATOM   6831 O  O   . GLN B  1 344 ? 67.00962 11.04898  -51.65371 1.000 34.92794 ? 343 GLN B O   1 
ATOM   6832 C  CB  . GLN B  1 344 ? 68.61639 11.79520  -54.51487 1.000 36.94936 ? 343 GLN B CB  1 
ATOM   6833 C  CG  . GLN B  1 344 ? 68.99799 11.08223  -55.80347 1.000 31.70381 ? 343 GLN B CG  1 
ATOM   6834 C  CD  . GLN B  1 344 ? 68.75617 11.92965  -57.03705 1.000 40.61370 ? 343 GLN B CD  1 
ATOM   6835 O  OE1 . GLN B  1 344 ? 68.62578 13.15104  -56.95070 1.000 42.66738 ? 343 GLN B OE1 1 
ATOM   6836 N  NE2 . GLN B  1 344 ? 68.69257 11.28263  -58.19559 1.000 34.32241 ? 343 GLN B NE2 1 
ATOM   6837 N  N   . LYS B  1 345 ? 68.59657 12.64521  -51.56189 1.000 32.12400 ? 344 LYS B N   1 
ATOM   6838 C  CA  . LYS B  1 345 ? 67.92538 13.36342  -50.48843 1.000 31.96914 ? 344 LYS B CA  1 
ATOM   6839 C  C   . LYS B  1 345 ? 66.58747 13.90451  -50.97727 1.000 40.11080 ? 344 LYS B C   1 
ATOM   6840 O  O   . LYS B  1 345 ? 66.48132 14.43779  -52.08533 1.000 43.22604 ? 344 LYS B O   1 
ATOM   6841 C  CB  . LYS B  1 345 ? 68.81073 14.50268  -49.97980 1.000 27.00770 ? 344 LYS B CB  1 
ATOM   6842 C  CG  . LYS B  1 345 ? 68.12482 15.45526  -49.01245 1.000 27.83010 ? 344 LYS B CG  1 
ATOM   6843 C  CD  . LYS B  1 345 ? 69.09932 16.50076  -48.48952 1.000 36.56475 ? 344 LYS B CD  1 
ATOM   6844 C  CE  . LYS B  1 345 ? 68.37571 17.66060  -47.82027 1.000 34.28869 ? 344 LYS B CE  1 
ATOM   6845 N  NZ  . LYS B  1 345 ? 67.54124 17.22328  -46.66717 1.000 39.39704 ? 344 LYS B NZ  1 
ATOM   6846 N  N   . ASP B  1 346 ? 65.55686 13.74781  -50.15006 1.000 36.21702 ? 345 ASP B N   1 
ATOM   6847 C  CA  . ASP B  1 346 ? 64.21720 14.21777  -50.49536 1.000 32.65023 ? 345 ASP B CA  1 
ATOM   6848 C  C   . ASP B  1 346 ? 64.20146 15.73886  -50.43890 1.000 31.88506 ? 345 ASP B C   1 
ATOM   6849 O  O   . ASP B  1 346 ? 64.14788 16.33474  -49.36113 1.000 32.81727 ? 345 ASP B O   1 
ATOM   6850 C  CB  . ASP B  1 346 ? 63.17938 13.62038  -49.55272 1.000 27.06526 ? 345 ASP B CB  1 
ATOM   6851 C  CG  . ASP B  1 346 ? 61.75750 13.98965  -49.93824 1.000 28.09922 ? 345 ASP B CG  1 
ATOM   6852 O  OD1 . ASP B  1 346 ? 61.55808 14.55144  -51.03687 1.000 23.18170 ? 345 ASP B OD1 1 
ATOM   6853 O  OD2 . ASP B  1 346 ? 60.83672 13.72041  -49.13777 1.000 29.87343 ? 345 ASP B OD2 1 
ATOM   6854 N  N   . THR B  1 347 ? 64.24687 16.37346  -51.60749 1.000 32.04591 ? 346 THR B N   1 
ATOM   6855 C  CA  . THR B  1 347 ? 64.21158 17.82428  -51.71340 1.000 32.48370 ? 346 THR B CA  1 
ATOM   6856 C  C   . THR B  1 347 ? 62.83491 18.35440  -52.08866 1.000 31.11705 ? 346 THR B C   1 
ATOM   6857 O  O   . THR B  1 347 ? 62.67585 19.56938  -52.24071 1.000 30.84082 ? 346 THR B O   1 
ATOM   6858 C  CB  . THR B  1 347 ? 65.24491 18.30533  -52.73890 1.000 36.79482 ? 346 THR B CB  1 
ATOM   6859 O  OG1 . THR B  1 347 ? 64.90203 17.80649  -54.03814 1.000 37.56588 ? 346 THR B OG1 1 
ATOM   6860 C  CG2 . THR B  1 347 ? 66.63241 17.80849  -52.36631 1.000 29.06323 ? 346 THR B CG2 1 
ATOM   6861 N  N   . SER B  1 348 ? 61.84349 17.47921  -52.24307 1.000 28.21053 ? 347 SER B N   1 
ATOM   6862 C  CA  . SER B  1 348 ? 60.50082 17.91490  -52.59318 1.000 27.71118 ? 347 SER B CA  1 
ATOM   6863 C  C   . SER B  1 348 ? 59.88871 18.73066  -51.45690 1.000 27.94715 ? 347 SER B C   1 
ATOM   6864 O  O   . SER B  1 348 ? 60.26779 18.60586  -50.28894 1.000 29.15148 ? 347 SER B O   1 
ATOM   6865 C  CB  . SER B  1 348 ? 59.61487 16.71315  -52.92212 1.000 24.00182 ? 347 SER B CB  1 
ATOM   6866 O  OG  . SER B  1 348 ? 59.60889 15.77538  -51.86080 1.000 23.97971 ? 347 SER B OG  1 
ATOM   6867 N  N   . SER B  1 349 ? 58.92417 19.57469  -51.81406 1.000 20.88962 ? 348 SER B N   1 
ATOM   6868 C  CA  . SER B  1 349 ? 58.34938 20.53599  -50.88657 1.000 27.98875 ? 348 SER B CA  1 
ATOM   6869 C  C   . SER B  1 349 ? 56.87763 20.24071  -50.63066 1.000 29.22132 ? 348 SER B C   1 
ATOM   6870 O  O   . SER B  1 349 ? 56.16648 19.71960  -51.49546 1.000 23.73688 ? 348 SER B O   1 
ATOM   6871 C  CB  . SER B  1 349 ? 58.49473 21.96931  -51.41495 1.000 30.17992 ? 348 SER B CB  1 
ATOM   6872 O  OG  . SER B  1 349 ? 59.85713 22.31204  -51.59956 1.000 38.21908 ? 348 SER B OG  1 
ATOM   6873 N  N   . LEU B  1 350 ? 56.43292 20.58461  -49.41931 1.000 31.81946 ? 349 LEU B N   1 
ATOM   6874 C  CA  . LEU B  1 350 ? 55.02332 20.59028  -49.03418 1.000 20.96427 ? 349 LEU B CA  1 
ATOM   6875 C  C   . LEU B  1 350 ? 54.69464 22.03322  -48.66585 1.000 21.57533 ? 349 LEU B C   1 
ATOM   6876 O  O   . LEU B  1 350 ? 54.63209 22.38612  -47.47843 1.000 21.38712 ? 349 LEU B O   1 
ATOM   6877 C  CB  . LEU B  1 350 ? 54.75232 19.62202  -47.88205 1.000 21.57984 ? 349 LEU B CB  1 
ATOM   6878 C  CG  . LEU B  1 350 ? 53.31228 19.28143  -47.47474 1.000 20.27973 ? 349 LEU B CG  1 
ATOM   6879 C  CD1 . LEU B  1 350 ? 52.89672 20.03757  -46.22102 1.000 19.22003 ? 349 LEU B CD1 1 
ATOM   6880 C  CD2 . LEU B  1 350 ? 52.33086 19.54261  -48.61089 1.000 24.01271 ? 349 LEU B CD2 1 
ATOM   6881 N  N   . PRO B  1 351 ? 54.49847 22.89939  -49.65786 1.000 28.69301 ? 350 PRO B N   1 
ATOM   6882 C  CA  . PRO B  1 351 ? 54.37406 24.33224  -49.37028 1.000 29.31706 ? 350 PRO B CA  1 
ATOM   6883 C  C   . PRO B  1 351 ? 53.06167 24.67191  -48.68355 1.000 25.72494 ? 350 PRO B C   1 
ATOM   6884 O  O   . PRO B  1 351 ? 52.02900 24.03549  -48.90456 1.000 23.60505 ? 350 PRO B O   1 
ATOM   6885 C  CB  . PRO B  1 351 ? 54.45880 24.98018  -50.75711 1.000 26.01040 ? 350 PRO B CB  1 
ATOM   6886 C  CG  . PRO B  1 351 ? 53.99473 23.92399  -51.69223 1.000 23.16990 ? 350 PRO B CG  1 
ATOM   6887 C  CD  . PRO B  1 351 ? 54.42156 22.61106  -51.10087 1.000 20.35104 ? 350 PRO B CD  1 
ATOM   6888 N  N   . ARG B  1 352 ? 53.11797 25.70590  -47.84016 1.000 30.06626 ? 351 ARG B N   1 
ATOM   6889 C  CA  . ARG B  1 352 ? 51.93464 26.13471  -47.10195 1.000 33.44630 ? 351 ARG B CA  1 
ATOM   6890 C  C   . ARG B  1 352 ? 50.92568 26.82959  -48.00836 1.000 30.49203 ? 351 ARG B C   1 
ATOM   6891 O  O   . ARG B  1 352 ? 49.71926 26.78835  -47.73872 1.000 28.55570 ? 351 ARG B O   1 
ATOM   6892 C  CB  . ARG B  1 352 ? 52.34872 27.05374  -45.95217 1.000 30.87272 ? 351 ARG B CB  1 
ATOM   6893 C  CG  . ARG B  1 352 ? 51.23491 27.38919  -44.97393 1.000 43.67296 ? 351 ARG B CG  1 
ATOM   6894 C  CD  . ARG B  1 352 ? 51.02041 28.89037  -44.89795 1.000 49.36905 ? 351 ARG B CD  1 
ATOM   6895 N  NE  . ARG B  1 352 ? 52.28485 29.61593  -44.92669 1.000 53.15421 ? 351 ARG B NE  1 
ATOM   6896 C  CZ  . ARG B  1 352 ? 52.39040 30.93744  -44.92363 1.000 54.04873 ? 351 ARG B CZ  1 
ATOM   6897 N  NH1 . ARG B  1 352 ? 51.32149 31.71573  -44.87500 1.000 56.25121 ? 351 ARG B NH1 1 
ATOM   6898 N  NH2 . ARG B  1 352 ? 53.59842 31.49184  -44.97322 1.000 44.90773 ? 351 ARG B NH2 1 
ATOM   6899 N  N   . ILE B  1 353 ? 51.39313 27.46586  -49.07872 1.000 25.96055 ? 352 ILE B N   1 
ATOM   6900 C  CA  . ILE B  1 353 ? 50.53581 28.13166  -50.05120 1.000 23.40085 ? 352 ILE B CA  1 
ATOM   6901 C  C   . ILE B  1 353 ? 50.64140 27.37197  -51.36301 1.000 24.63808 ? 352 ILE B C   1 
ATOM   6902 O  O   . ILE B  1 353 ? 51.74609 27.02591  -51.80160 1.000 31.39573 ? 352 ILE B O   1 
ATOM   6903 C  CB  . ILE B  1 353 ? 50.92625 29.60761  -50.23135 1.000 29.91651 ? 352 ILE B CB  1 
ATOM   6904 C  CG1 . ILE B  1 353 ? 50.97766 30.30150  -48.86993 1.000 33.54924 ? 352 ILE B CG1 1 
ATOM   6905 C  CG2 . ILE B  1 353 ? 49.94101 30.30575  -51.15108 1.000 27.59687 ? 352 ILE B CG2 1 
ATOM   6906 C  CD1 . ILE B  1 353 ? 52.03707 31.37528  -48.77173 1.000 37.07549 ? 352 ILE B CD1 1 
ATOM   6907 N  N   . LEU B  1 354 ? 49.49497 27.10531  -51.98267 1.000 25.06648 ? 353 LEU B N   1 
ATOM   6908 C  CA  . LEU B  1 354 ? 49.45079 26.29025  -53.18596 1.000 26.02548 ? 353 LEU B CA  1 
ATOM   6909 C  C   . LEU B  1 354 ? 48.86159 26.98926  -54.40072 1.000 21.80850 ? 353 LEU B C   1 
ATOM   6910 O  O   . LEU B  1 354 ? 49.17534 26.59945  -55.52201 1.000 32.20432 ? 353 LEU B O   1 
ATOM   6911 C  CB  . LEU B  1 354 ? 48.64780 25.00436  -52.93140 1.000 19.79878 ? 353 LEU B CB  1 
ATOM   6912 C  CG  . LEU B  1 354 ? 49.12411 24.09835  -51.79004 1.000 20.14423 ? 353 LEU B CG  1 
ATOM   6913 C  CD1 . LEU B  1 354 ? 48.10867 23.00312  -51.48928 1.000 18.09944 ? 353 LEU B CD1 1 
ATOM   6914 C  CD2 . LEU B  1 354 ? 50.47678 23.49269  -52.11162 1.000 16.55491 ? 353 LEU B CD2 1 
ATOM   6915 N  N   . ARG B  1 355 ? 48.03313 28.01189  -54.21858 1.000 25.88793 ? 354 ARG B N   1 
ATOM   6916 C  CA  . ARG B  1 355 ? 47.24637 28.55270  -55.31919 1.000 31.39454 ? 354 ARG B CA  1 
ATOM   6917 C  C   . ARG B  1 355 ? 47.22738 30.07109  -55.39117 1.000 37.67884 ? 354 ARG B C   1 
ATOM   6918 O  O   . ARG B  1 355 ? 47.04216 30.60865  -56.49153 1.000 48.36122 ? 354 ARG B O   1 
ATOM   6919 C  CB  . ARG B  1 355 ? 45.79932 28.04455  -55.23339 1.000 31.39612 ? 354 ARG B CB  1 
ATOM   6920 C  CG  . ARG B  1 355 ? 44.95897 28.33028  -56.45636 1.000 33.11387 ? 354 ARG B CG  1 
ATOM   6921 C  CD  . ARG B  1 355 ? 43.50142 27.95720  -56.23253 1.000 33.96800 ? 354 ARG B CD  1 
ATOM   6922 N  NE  . ARG B  1 355 ? 42.65290 28.34739  -57.35313 1.000 37.41741 ? 354 ARG B NE  1 
ATOM   6923 C  CZ  . ARG B  1 355 ? 42.47461 27.61503  -58.44366 1.000 38.92282 ? 354 ARG B CZ  1 
ATOM   6924 N  NH1 . ARG B  1 355 ? 43.09131 26.45496  -58.60389 1.000 26.84879 ? 354 ARG B NH1 1 
ATOM   6925 N  NH2 . ARG B  1 355 ? 41.66145 28.05930  -59.39879 1.000 40.51019 ? 354 ARG B NH2 1 
ATOM   6926 N  N   . LYS B  1 356 ? 47.42708 30.77968  -54.27937 1.000 41.57578 ? 355 LYS B N   1 
ATOM   6927 C  CA  . LYS B  1 356 ? 47.37486 32.23756  -54.24167 1.000 49.10520 ? 355 LYS B CA  1 
ATOM   6928 C  C   . LYS B  1 356 ? 46.03118 32.75236  -54.73961 1.000 45.82961 ? 355 LYS B C   1 
ATOM   6929 O  O   . LYS B  1 356 ? 45.21057 33.22301  -53.94627 1.000 44.00164 ? 355 LYS B O   1 
ATOM   6930 C  CB  . LYS B  1 356 ? 48.51593 32.84713  -55.06295 1.000 46.53972 ? 355 LYS B CB  1 
ATOM   6931 C  CG  . LYS B  1 356 ? 49.62563 33.48499  -54.23696 1.000 51.77649 ? 355 LYS B CG  1 
ATOM   6932 C  CD  . LYS B  1 356 ? 50.74392 34.00283  -55.13923 1.000 55.37715 ? 355 LYS B CD  1 
ATOM   6933 C  CE  . LYS B  1 356 ? 50.48317 35.43166  -55.60580 1.000 60.46054 ? 355 LYS B CE  1 
ATOM   6934 N  NZ  . LYS B  1 356 ? 51.16045 35.73799  -56.90443 1.000 56.96553 ? 355 LYS B NZ  1 
ATOM   6935 N  N   . ARG B  1 357 ? 45.80219 32.66980  -56.04653 1.000 44.74102 ? 356 ARG B N   1 
ATOM   6936 C  CA  . ARG B  1 357 ? 44.57916 33.20907  -56.62108 1.000 48.39394 ? 356 ARG B CA  1 
ATOM   6937 C  C   . ARG B  1 357 ? 43.37131 32.40249  -56.14610 1.000 47.08380 ? 356 ARG B C   1 
ATOM   6938 O  O   . ARG B  1 357 ? 43.44549 31.17326  -56.03701 1.000 40.66111 ? 356 ARG B O   1 
ATOM   6939 C  CB  . ARG B  1 357 ? 44.65979 33.20090  -58.14996 1.000 48.48789 ? 356 ARG B CB  1 
ATOM   6940 C  CG  . ARG B  1 357 ? 45.96798 33.77232  -58.69119 1.000 54.54659 ? 356 ARG B CG  1 
ATOM   6941 C  CD  . ARG B  1 357 ? 45.83853 34.26000  -60.12757 1.000 46.56888 ? 356 ARG B CD  1 
ATOM   6942 N  NE  . ARG B  1 357 ? 46.81920 35.29960  -60.42082 1.000 52.04132 ? 356 ARG B NE  1 
ATOM   6943 C  CZ  . ARG B  1 357 ? 47.95447 35.10510  -61.07861 1.000 67.16195 ? 356 ARG B CZ  1 
ATOM   6944 N  NH1 . ARG B  1 357 ? 48.27629 33.91899  -61.56871 1.000 73.40133 ? 356 ARG B NH1 1 
ATOM   6945 N  NH2 . ARG B  1 357 ? 48.78535 36.12892  -61.25459 1.000 63.01128 ? 356 ARG B NH2 1 
ATOM   6946 N  N   . PRO B  1 358 ? 42.24661 33.05782  -55.84867 1.000 48.50498 ? 357 PRO B N   1 
ATOM   6947 C  CA  . PRO B  1 358 ? 41.08242 32.32907  -55.32505 1.000 46.44888 ? 357 PRO B CA  1 
ATOM   6948 C  C   . PRO B  1 358 ? 40.41223 31.44884  -56.36851 1.000 48.21405 ? 357 PRO B C   1 
ATOM   6949 O  O   . PRO B  1 358 ? 40.88504 31.34068  -57.50484 1.000 43.94190 ? 357 PRO B O   1 
ATOM   6950 C  CB  . PRO B  1 358 ? 40.14178 33.45150  -54.86155 1.000 42.54942 ? 357 PRO B CB  1 
ATOM   6951 C  CG  . PRO B  1 358 ? 40.99695 34.68363  -54.78018 1.000 42.22826 ? 357 PRO B CG  1 
ATOM   6952 C  CD  . PRO B  1 358 ? 42.03363 34.51318  -55.84176 1.000 36.04845 ? 357 PRO B CD  1 
ATOM   6953 N  N   . PHE B  1 359 ? 39.30690 30.81512  -55.98802 1.000 47.03969 ? 358 PHE B N   1 
ATOM   6954 C  CA  . PHE B  1 359 ? 38.55018 29.97852  -56.91214 1.000 44.11773 ? 358 PHE B CA  1 
ATOM   6955 C  C   . PHE B  1 359 ? 37.52931 30.81514  -57.67781 1.000 37.96936 ? 358 PHE B C   1 
ATOM   6956 O  O   . PHE B  1 359 ? 37.19050 30.50725  -58.82028 1.000 49.02963 ? 358 PHE B O   1 
ATOM   6957 C  CB  . PHE B  1 359 ? 37.84569 28.84112  -56.16683 1.000 37.42347 ? 358 PHE B CB  1 
ATOM   6958 C  CG  . PHE B  1 359 ? 38.76385 28.00866  -55.31744 1.000 28.52492 ? 358 PHE B CG  1 
ATOM   6959 C  CD1 . PHE B  1 359 ? 39.64815 27.11594  -55.89807 1.000 22.70346 ? 358 PHE B CD1 1 
ATOM   6960 C  CD2 . PHE B  1 359 ? 38.73446 28.11216  -53.93637 1.000 32.62902 ? 358 PHE B CD2 1 
ATOM   6961 C  CE1 . PHE B  1 359 ? 40.49306 26.34769  -55.11725 1.000 23.09932 ? 358 PHE B CE1 1 
ATOM   6962 C  CE2 . PHE B  1 359 ? 39.57540 27.34511  -53.15045 1.000 26.66331 ? 358 PHE B CE2 1 
ATOM   6963 C  CZ  . PHE B  1 359 ? 40.45601 26.46288  -53.74185 1.000 18.37835 ? 358 PHE B CZ  1 
ATOM   6964 N  N   . HIS B  1 363 ? 29.98612 35.98314  -57.48344 1.000 50.28913 ? 362 HIS B N   1 
ATOM   6965 C  CA  . HIS B  1 363 ? 29.52721 36.68743  -58.67457 1.000 44.99861 ? 362 HIS B CA  1 
ATOM   6966 C  C   . HIS B  1 363 ? 28.07679 37.13577  -58.50565 1.000 49.65667 ? 362 HIS B C   1 
ATOM   6967 O  O   . HIS B  1 363 ? 27.58651 37.26109  -57.38316 1.000 49.31531 ? 362 HIS B O   1 
ATOM   6968 C  CB  . HIS B  1 363 ? 29.68150 35.80224  -59.91429 1.000 42.65399 ? 362 HIS B CB  1 
ATOM   6969 C  CG  . HIS B  1 363 ? 31.08880 35.35115  -60.16216 1.000 59.56904 ? 362 HIS B CG  1 
ATOM   6970 N  ND1 . HIS B  1 363 ? 32.16772 35.86750  -59.47645 1.000 60.48274 ? 362 HIS B ND1 1 
ATOM   6971 C  CD2 . HIS B  1 363 ? 31.59343 34.42913  -61.01655 1.000 51.38494 ? 362 HIS B CD2 1 
ATOM   6972 C  CE1 . HIS B  1 363 ? 33.27572 35.28471  -59.89841 1.000 58.62863 ? 362 HIS B CE1 1 
ATOM   6973 N  NE2 . HIS B  1 363 ? 32.95505 34.40802  -60.83312 1.000 58.26947 ? 362 HIS B NE2 1 
ATOM   6974 N  N   . LYS B  1 364 ? 27.38920 37.36980  -59.62586 1.000 44.88552 ? 363 LYS B N   1 
ATOM   6975 C  CA  . LYS B  1 364 ? 26.05007 37.94580  -59.55823 1.000 43.68250 ? 363 LYS B CA  1 
ATOM   6976 C  C   . LYS B  1 364 ? 25.01319 36.93352  -59.08483 1.000 45.94391 ? 363 LYS B C   1 
ATOM   6977 O  O   . LYS B  1 364 ? 24.06273 37.30967  -58.38857 1.000 58.26211 ? 363 LYS B O   1 
ATOM   6978 C  CB  . LYS B  1 364 ? 25.65465 38.50869  -60.92247 1.000 50.06512 ? 363 LYS B CB  1 
ATOM   6979 C  CG  . LYS B  1 364 ? 24.49423 39.49129  -60.88411 1.000 51.02329 ? 363 LYS B CG  1 
ATOM   6980 C  CD  . LYS B  1 364 ? 24.02872 39.82994  -62.29065 1.000 57.93603 ? 363 LYS B CD  1 
ATOM   6981 C  CE  . LYS B  1 364 ? 25.19667 40.25348  -63.16805 1.000 55.21786 ? 363 LYS B CE  1 
ATOM   6982 N  NZ  . LYS B  1 364 ? 24.82994 40.25934  -64.60954 1.000 62.72497 ? 363 LYS B NZ  1 
ATOM   6983 N  N   . ILE B  1 365 ? 25.18131 35.65897  -59.44452 1.000 32.82222 ? 364 ILE B N   1 
ATOM   6984 C  CA  . ILE B  1 365 ? 24.22354 34.59370  -59.14903 1.000 35.49720 ? 364 ILE B CA  1 
ATOM   6985 C  C   . ILE B  1 365 ? 22.88605 34.91210  -59.80479 1.000 31.59519 ? 364 ILE B C   1 
ATOM   6986 O  O   . ILE B  1 365 ? 22.06737 35.65589  -59.25291 1.000 29.40463 ? 364 ILE B O   1 
ATOM   6987 C  CB  . ILE B  1 365 ? 24.06031 34.36802  -57.63454 1.000 25.69771 ? 364 ILE B CB  1 
ATOM   6988 C  CG1 . ILE B  1 365 ? 25.40814 34.01427  -57.00604 1.000 34.26768 ? 364 ILE B CG1 1 
ATOM   6989 C  CG2 . ILE B  1 365 ? 23.04855 33.26267  -57.36980 1.000 23.98274 ? 364 ILE B CG2 1 
ATOM   6990 C  CD1 . ILE B  1 365 ? 25.33344 33.71652  -55.53011 1.000 34.90270 ? 364 ILE B CD1 1 
ATOM   6991 N  N   . ASN B  1 366 ? 22.65393 34.33603  -60.98375 1.000 22.45062 ? 365 ASN B N   1 
ATOM   6992 C  CA  . ASN B  1 366 ? 21.47336 34.63946  -61.78187 1.000 27.66680 ? 365 ASN B CA  1 
ATOM   6993 C  C   . ASN B  1 366 ? 20.31059 33.69456  -61.50407 1.000 26.73842 ? 365 ASN B C   1 
ATOM   6994 O  O   . ASN B  1 366 ? 19.15431 34.12930  -61.47663 1.000 25.76500 ? 365 ASN B O   1 
ATOM   6995 C  CB  . ASN B  1 366 ? 21.82401 34.58400  -63.27204 1.000 33.37721 ? 365 ASN B CB  1 
ATOM   6996 C  CG  . ASN B  1 366 ? 23.05799 35.39583  -63.61274 1.000 36.06829 ? 365 ASN B CG  1 
ATOM   6997 O  OD1 . ASN B  1 366 ? 24.18133 34.99877  -63.30197 1.000 33.30943 ? 365 ASN B OD1 1 
ATOM   6998 N  ND2 . ASN B  1 366 ? 22.85619 36.53485  -64.26443 1.000 40.71056 ? 365 ASN B ND2 1 
ATOM   6999 N  N   . THR B  1 367 ? 20.59044 32.41090  -61.29637 1.000 20.99713 ? 366 THR B N   1 
ATOM   7000 C  CA  . THR B  1 367 ? 19.56193 31.38384  -61.29278 1.000 16.12942 ? 366 THR B CA  1 
ATOM   7001 C  C   . THR B  1 367 ? 19.67997 30.51506  -60.04785 1.000 14.45163 ? 366 THR B C   1 
ATOM   7002 O  O   . THR B  1 367 ? 20.77628 30.28011  -59.53304 1.000 12.68697 ? 366 THR B O   1 
ATOM   7003 C  CB  . THR B  1 367 ? 19.66635 30.51400  -62.55800 1.000 13.55295 ? 366 THR B CB  1 
ATOM   7004 O  OG1 . THR B  1 367 ? 19.70154 31.35938  -63.71448 1.000 22.27277 ? 366 THR B OG1 1 
ATOM   7005 C  CG2 . THR B  1 367 ? 18.48806 29.55959  -62.67431 1.000 17.04567 ? 366 THR B CG2 1 
ATOM   7006 N  N   . LEU B  1 368 ? 18.52956 30.05309  -59.56331 1.000 13.88610 ? 367 LEU B N   1 
ATOM   7007 C  CA  . LEU B  1 368 ? 18.44270 29.06538  -58.49895 1.000 14.52748 ? 367 LEU B CA  1 
ATOM   7008 C  C   . LEU B  1 368 ? 17.70078 27.84533  -59.02286 1.000 12.79553 ? 367 LEU B C   1 
ATOM   7009 O  O   . LEU B  1 368 ? 16.71313 27.97801  -59.75233 1.000 16.53899 ? 367 LEU B O   1 
ATOM   7010 C  CB  . LEU B  1 368 ? 17.71941 29.62630  -57.27269 1.000 16.30337 ? 367 LEU B CB  1 
ATOM   7011 C  CG  . LEU B  1 368 ? 18.26707 30.91679  -56.66282 1.000 16.26776 ? 367 LEU B CG  1 
ATOM   7012 C  CD1 . LEU B  1 368 ? 17.38495 31.35054  -55.50789 1.000 16.32700 ? 367 LEU B CD1 1 
ATOM   7013 C  CD2 . LEU B  1 368 ? 19.70484 30.73307  -56.20247 1.000 15.73095 ? 367 LEU B CD2 1 
ATOM   7014 N  N   . ARG B  1 369 ? 18.17636 26.65723  -58.65523 1.000 11.97195 ? 368 ARG B N   1 
ATOM   7015 C  CA  . ARG B  1 369 ? 17.57929 25.41159  -59.11747 1.000 12.00685 ? 368 ARG B CA  1 
ATOM   7016 C  C   . ARG B  1 369 ? 17.42943 24.44430  -57.95552 1.000 14.27272 ? 368 ARG B C   1 
ATOM   7017 O  O   . ARG B  1 369 ? 18.36431 24.25825  -57.17036 1.000 16.98499 ? 368 ARG B O   1 
ATOM   7018 C  CB  . ARG B  1 369 ? 18.41534 24.76885  -60.22894 1.000 12.78576 ? 368 ARG B CB  1 
ATOM   7019 C  CG  . ARG B  1 369 ? 18.51574 25.61440  -61.48213 1.000 15.50526 ? 368 ARG B CG  1 
ATOM   7020 C  CD  . ARG B  1 369 ? 19.29006 24.90935  -62.57893 1.000 14.95368 ? 368 ARG B CD  1 
ATOM   7021 N  NE  . ARG B  1 369 ? 19.62188 25.83361  -63.65544 1.000 17.12306 ? 368 ARG B NE  1 
ATOM   7022 C  CZ  . ARG B  1 369 ? 18.83437 26.09583  -64.68899 1.000 16.38744 ? 368 ARG B CZ  1 
ATOM   7023 N  NH1 . ARG B  1 369 ? 17.66912 25.48760  -64.84277 1.000 13.26687 ? 368 ARG B NH1 1 
ATOM   7024 N  NH2 . ARG B  1 369 ? 19.22445 26.99373  -65.58917 1.000 19.71093 ? 368 ARG B NH2 1 
ATOM   7025 N  N   . ASN B  1 370 ? 16.25033 23.84038  -57.84863 1.000 19.60658 ? 369 ASN B N   1 
ATOM   7026 C  CA  . ASN B  1 370 ? 15.99283 22.74941  -56.92048 1.000 18.17925 ? 369 ASN B CA  1 
ATOM   7027 C  C   . ASN B  1 370 ? 15.91352 21.45312  -57.71141 1.000 19.10305 ? 369 ASN B C   1 
ATOM   7028 O  O   . ASN B  1 370 ? 15.13734 21.35180  -58.66727 1.000 26.18071 ? 369 ASN B O   1 
ATOM   7029 C  CB  . ASN B  1 370 ? 14.69759 22.97625  -56.13940 1.000 16.50676 ? 369 ASN B CB  1 
ATOM   7030 C  CG  . ASN B  1 370 ? 14.78692 24.15445  -55.19696 1.000 19.20959 ? 369 ASN B CG  1 
ATOM   7031 O  OD1 . ASN B  1 370 ? 15.87810 24.63436  -54.89023 1.000 22.67218 ? 369 ASN B OD1 1 
ATOM   7032 N  ND2 . ASN B  1 370 ? 13.63749 24.62294  -54.72231 1.000 23.14676 ? 369 ASN B ND2 1 
ATOM   7033 N  N   . LEU B  1 371 ? 16.72619 20.47284  -57.32445 1.000 16.37682 ? 370 LEU B N   1 
ATOM   7034 C  CA  . LEU B  1 371 ? 16.82798 19.21000  -58.04528 1.000 15.68651 ? 370 LEU B CA  1 
ATOM   7035 C  C   . LEU B  1 371 ? 16.76058 18.07137  -57.03953 1.000 18.07663 ? 370 LEU B C   1 
ATOM   7036 O  O   . LEU B  1 371 ? 17.57446 18.01058  -56.11267 1.000 18.97749 ? 370 LEU B O   1 
ATOM   7037 C  CB  . LEU B  1 371 ? 18.12243 19.14934  -58.86359 1.000 16.89396 ? 370 LEU B CB  1 
ATOM   7038 C  CG  . LEU B  1 371 ? 18.43292 20.42859  -59.65268 1.000 15.08823 ? 370 LEU B CG  1 
ATOM   7039 C  CD1 . LEU B  1 371 ? 19.50628 21.25700  -58.96018 1.000 13.36018 ? 370 LEU B CD1 1 
ATOM   7040 C  CD2 . LEU B  1 371 ? 18.81789 20.13703  -61.08989 1.000 13.82227 ? 370 LEU B CD2 1 
ATOM   7041 N  N   . SER B  1 372 ? 15.79340 17.17768  -57.21957 1.000 18.42792 ? 371 SER B N   1 
ATOM   7042 C  CA  . SER B  1 372 ? 15.53741 16.10017  -56.27718 1.000 16.10374 ? 371 SER B CA  1 
ATOM   7043 C  C   . SER B  1 372 ? 16.20168 14.80624  -56.73037 1.000 19.41884 ? 371 SER B C   1 
ATOM   7044 O  O   . SER B  1 372 ? 16.36523 14.55053  -57.92631 1.000 15.05003 ? 371 SER B O   1 
ATOM   7045 C  CB  . SER B  1 372 ? 14.03437 15.86790  -56.10939 1.000 17.34989 ? 371 SER B CB  1 
ATOM   7046 O  OG  . SER B  1 372 ? 13.46199 15.34667  -57.29676 1.000 21.04734 ? 371 SER B OG  1 
ATOM   7047 N  N   . LEU B  1 373 ? 16.58037 13.98984  -55.75252 1.000 15.29801 ? 372 LEU B N   1 
ATOM   7048 C  CA  . LEU B  1 373 ? 17.09602 12.64794  -55.98442 1.000 13.17168 ? 372 LEU B CA  1 
ATOM   7049 C  C   . LEU B  1 373 ? 16.08304 11.65692  -55.42996 1.000 18.40079 ? 372 LEU B C   1 
ATOM   7050 O  O   . LEU B  1 373 ? 15.75032 11.70682  -54.24067 1.000 24.85661 ? 372 LEU B O   1 
ATOM   7051 C  CB  . LEU B  1 373 ? 18.45862 12.45751  -55.31858 1.000 17.29485 ? 372 LEU B CB  1 
ATOM   7052 C  CG  . LEU B  1 373 ? 19.49019 13.56656  -55.53145 1.000 15.00474 ? 372 LEU B CG  1 
ATOM   7053 C  CD1 . LEU B  1 373 ? 20.75967 13.27145  -54.75261 1.000 11.01729 ? 372 LEU B CD1 1 
ATOM   7054 C  CD2 . LEU B  1 373 ? 19.79376 13.74313  -57.00653 1.000 14.18099 ? 372 LEU B CD2 1 
ATOM   7055 N  N   . GLY B  1 374 ? 15.59114 10.77436  -56.28221 1.000 18.98043 ? 373 GLY B N   1 
ATOM   7056 C  CA  . GLY B  1 374 ? 14.58751 9.82523   -55.86641 1.000 20.96360 ? 373 GLY B CA  1 
ATOM   7057 C  C   . GLY B  1 374 ? 14.58170 8.58988   -56.73149 1.000 20.25771 ? 373 GLY B C   1 
ATOM   7058 O  O   . GLY B  1 374 ? 15.53339 8.31542   -57.46400 1.000 20.19053 ? 373 GLY B O   1 
ATOM   7059 N  N   . ALA B  1 375 ? 13.48592 7.84037   -56.63998 1.000 22.42619 ? 374 ALA B N   1 
ATOM   7060 C  CA  . ALA B  1 375 ? 13.35086 6.60229   -57.39068 1.000 28.27883 ? 374 ALA B CA  1 
ATOM   7061 C  C   . ALA B  1 375 ? 11.87479 6.28270   -57.56755 1.000 25.17337 ? 374 ALA B C   1 
ATOM   7062 O  O   . ALA B  1 375 ? 11.06482 6.54778   -56.67621 1.000 26.22924 ? 374 ALA B O   1 
ATOM   7063 C  CB  . ALA B  1 375 ? 14.06573 5.44124   -56.68817 1.000 21.47728 ? 374 ALA B CB  1 
ATOM   7064 N  N   . SER B  1 376 ? 11.53871 5.72207   -58.72199 1.000 23.43033 ? 375 SER B N   1 
ATOM   7065 C  CA  . SER B  1 376 ? 10.20891 5.20942   -59.01713 1.000 27.73246 ? 375 SER B CA  1 
ATOM   7066 C  C   . SER B  1 376 ? 10.31246 3.72253   -59.33976 1.000 30.78488 ? 375 SER B C   1 
ATOM   7067 O  O   . SER B  1 376 ? 11.40282 3.15161   -59.39636 1.000 35.21076 ? 375 SER B O   1 
ATOM   7068 C  CB  . SER B  1 376 ? 9.56425  5.97956   -60.17386 1.000 21.28177 ? 375 SER B CB  1 
ATOM   7069 O  OG  . SER B  1 376 ? 9.30759  7.32478   -59.81367 1.000 33.17359 ? 375 SER B OG  1 
ATOM   7070 N  N   . LEU B  1 377 ? 9.16224  3.09317   -59.55155 1.000 31.58804 ? 376 LEU B N   1 
ATOM   7071 C  CA  . LEU B  1 377 ? 9.09162  1.68219   -59.90237 1.000 26.75923 ? 376 LEU B CA  1 
ATOM   7072 C  C   . LEU B  1 377 ? 8.58110  1.54328   -61.32824 1.000 29.19960 ? 376 LEU B C   1 
ATOM   7073 O  O   . LEU B  1 377 ? 7.60454  2.19789   -61.70757 1.000 30.60855 ? 376 LEU B O   1 
ATOM   7074 C  CB  . LEU B  1 377 ? 8.18148  0.92014   -58.93683 1.000 25.29779 ? 376 LEU B CB  1 
ATOM   7075 C  CG  . LEU B  1 377 ? 8.68308  0.77337   -57.49948 1.000 24.87574 ? 376 LEU B CG  1 
ATOM   7076 C  CD1 . LEU B  1 377 ? 7.62891  0.10786   -56.63097 1.000 16.18966 ? 376 LEU B CD1 1 
ATOM   7077 C  CD2 . LEU B  1 377 ? 9.98462  -0.01457  -57.46387 1.000 23.00710 ? 376 LEU B CD2 1 
ATOM   7078 N  N   . ASP B  1 378 ? 9.24383  0.69951   -62.11373 1.000 27.91592 ? 377 ASP B N   1 
ATOM   7079 C  CA  . ASP B  1 378 ? 8.80057  0.41218   -63.46797 1.000 33.04052 ? 377 ASP B CA  1 
ATOM   7080 C  C   . ASP B  1 378 ? 7.76907  -0.71660  -63.42892 1.000 36.66748 ? 377 ASP B C   1 
ATOM   7081 O  O   . ASP B  1 378 ? 7.33341  -1.15136  -62.35938 1.000 34.98720 ? 377 ASP B O   1 
ATOM   7082 C  CB  . ASP B  1 378 ? 9.99777  0.08787   -64.36243 1.000 30.74826 ? 377 ASP B CB  1 
ATOM   7083 C  CG  . ASP B  1 378 ? 10.79805 -1.10547  -63.87112 1.000 31.11182 ? 377 ASP B CG  1 
ATOM   7084 O  OD1 . ASP B  1 378 ? 10.44426 -1.68213  -62.82233 1.000 32.57159 ? 377 ASP B OD1 1 
ATOM   7085 O  OD2 . ASP B  1 378 ? 11.78819 -1.46840  -64.54089 1.000 32.81983 ? 377 ASP B OD2 1 
ATOM   7086 N  N   . GLN B  1 379 ? 7.37047  -1.20985  -64.60416 1.000 37.01190 ? 378 GLN B N   1 
ATOM   7087 C  CA  . GLN B  1 379 ? 6.34173  -2.24386  -64.65905 1.000 36.47162 ? 378 GLN B CA  1 
ATOM   7088 C  C   . GLN B  1 379 ? 6.81466  -3.55143  -64.03556 1.000 39.52584 ? 378 GLN B C   1 
ATOM   7089 O  O   . GLN B  1 379 ? 6.00103  -4.30378  -63.48792 1.000 43.19531 ? 378 GLN B O   1 
ATOM   7090 C  CB  . GLN B  1 379 ? 5.90638  -2.47405  -66.10576 1.000 32.81959 ? 378 GLN B CB  1 
ATOM   7091 C  CG  . GLN B  1 379 ? 7.02534  -2.93962  -67.01997 1.000 35.26739 ? 378 GLN B CG  1 
ATOM   7092 C  CD  . GLN B  1 379 ? 6.58285  -3.07375  -68.45984 1.000 31.71872 ? 378 GLN B CD  1 
ATOM   7093 O  OE1 . GLN B  1 379 ? 6.25875  -4.16789  -68.92275 1.000 41.21244 ? 378 GLN B OE1 1 
ATOM   7094 N  NE2 . GLN B  1 379 ? 6.56833  -1.95813  -69.17969 1.000 30.42248 ? 378 GLN B NE2 1 
ATOM   7095 N  N   . TYR B  1 380 ? 8.11309  -3.83768  -64.10031 1.000 33.37967 ? 379 TYR B N   1 
ATOM   7096 C  CA  . TYR B  1 380 ? 8.64925  -5.07770  -63.55632 1.000 29.10087 ? 379 TYR B CA  1 
ATOM   7097 C  C   . TYR B  1 380 ? 8.92962  -4.99922  -62.06168 1.000 31.00219 ? 379 TYR B C   1 
ATOM   7098 O  O   . TYR B  1 380 ? 9.43156  -5.97431  -61.49128 1.000 27.37799 ? 379 TYR B O   1 
ATOM   7099 C  CB  . TYR B  1 380 ? 9.93017  -5.46418  -64.30008 1.000 30.40031 ? 379 TYR B CB  1 
ATOM   7100 C  CG  . TYR B  1 380 ? 9.78857  -5.45975  -65.80498 1.000 30.59074 ? 379 TYR B CG  1 
ATOM   7101 C  CD1 . TYR B  1 380 ? 9.15118  -6.50166  -66.46472 1.000 34.32452 ? 379 TYR B CD1 1 
ATOM   7102 C  CD2 . TYR B  1 380 ? 10.29634 -4.41596  -66.56627 1.000 29.55247 ? 379 TYR B CD2 1 
ATOM   7103 C  CE1 . TYR B  1 380 ? 9.02007  -6.50335  -67.83997 1.000 30.94238 ? 379 TYR B CE1 1 
ATOM   7104 C  CE2 . TYR B  1 380 ? 10.17083 -4.40866  -67.94297 1.000 34.91598 ? 379 TYR B CE2 1 
ATOM   7105 C  CZ  . TYR B  1 380 ? 9.53173  -5.45503  -68.57433 1.000 36.88340 ? 379 TYR B CZ  1 
ATOM   7106 O  OH  . TYR B  1 380 ? 9.40384  -5.45352  -69.94476 1.000 39.06346 ? 379 TYR B OH  1 
ATOM   7107 N  N   . GLY B  1 381 ? 8.62122  -3.87565  -61.41774 1.000 34.39067 ? 380 GLY B N   1 
ATOM   7108 C  CA  . GLY B  1 381 ? 8.90012  -3.70929  -60.00690 1.000 28.79822 ? 380 GLY B CA  1 
ATOM   7109 C  C   . GLY B  1 381 ? 10.30967 -3.27612  -59.67718 1.000 29.07682 ? 380 GLY B C   1 
ATOM   7110 O  O   . GLY B  1 381 ? 10.69461 -3.32153  -58.50252 1.000 22.87347 ? 380 GLY B O   1 
ATOM   7111 N  N   . ARG B  1 382 ? 11.09316 -2.85782  -60.67189 1.000 22.98265 ? 381 ARG B N   1 
ATOM   7112 C  CA  . ARG B  1 382 ? 12.47077 -2.43199  -60.45638 1.000 26.31874 ? 381 ARG B CA  1 
ATOM   7113 C  C   . ARG B  1 382 ? 12.52185 -0.94855  -60.10549 1.000 25.37012 ? 381 ARG B C   1 
ATOM   7114 O  O   . ARG B  1 382 ? 11.75230 -0.15344  -60.65399 1.000 24.39591 ? 381 ARG B O   1 
ATOM   7115 C  CB  . ARG B  1 382 ? 13.31680 -2.68111  -61.70035 1.000 27.41545 ? 381 ARG B CB  1 
ATOM   7116 C  CG  . ARG B  1 382 ? 13.34577 -4.12349  -62.15525 1.000 24.49631 ? 381 ARG B CG  1 
ATOM   7117 C  CD  . ARG B  1 382 ? 14.20441 -4.29018  -63.39742 1.000 29.24082 ? 381 ARG B CD  1 
ATOM   7118 N  NE  . ARG B  1 382 ? 13.70476 -3.50887  -64.52212 1.000 21.76628 ? 381 ARG B NE  1 
ATOM   7119 C  CZ  . ARG B  1 382 ? 14.20063 -3.56552  -65.75051 1.000 26.09442 ? 381 ARG B CZ  1 
ATOM   7120 N  NH1 . ARG B  1 382 ? 15.21218 -4.36334  -66.05125 1.000 27.51573 ? 381 ARG B NH1 1 
ATOM   7121 N  NH2 . ARG B  1 382 ? 13.66677 -2.80440  -66.70171 1.000 29.64631 ? 381 ARG B NH2 1 
ATOM   7122 N  N   . PRO B  1 383 ? 13.41683 -0.55662  -59.20033 1.000 24.06005 ? 382 PRO B N   1 
ATOM   7123 C  CA  . PRO B  1 383 ? 13.56897 0.87020   -58.88860 1.000 21.19788 ? 382 PRO B CA  1 
ATOM   7124 C  C   . PRO B  1 383 ? 14.22600 1.61075   -60.04418 1.000 18.07870 ? 382 PRO B C   1 
ATOM   7125 O  O   . PRO B  1 383 ? 15.22000 1.15217   -60.61122 1.000 23.00925 ? 382 PRO B O   1 
ATOM   7126 C  CB  . PRO B  1 383 ? 14.45526 0.86942   -57.63821 1.000 20.28957 ? 382 PRO B CB  1 
ATOM   7127 C  CG  . PRO B  1 383 ? 15.21286 -0.40816  -57.72277 1.000 20.22158 ? 382 PRO B CG  1 
ATOM   7128 C  CD  . PRO B  1 383 ? 14.28948 -1.40320  -58.36998 1.000 20.03458 ? 382 PRO B CD  1 
ATOM   7129 N  N   . VAL B  1 384 ? 13.65622 2.75783   -60.39239 1.000 20.76690 ? 383 VAL B N   1 
ATOM   7130 C  CA  . VAL B  1 384 ? 14.17709 3.62413   -61.44214 1.000 19.81478 ? 383 VAL B CA  1 
ATOM   7131 C  C   . VAL B  1 384 ? 14.64870 4.90093   -60.75965 1.000 22.95700 ? 383 VAL B C   1 
ATOM   7132 O  O   . VAL B  1 384 ? 13.84218 5.78532   -60.45064 1.000 24.59516 ? 383 VAL B O   1 
ATOM   7133 C  CB  . VAL B  1 384 ? 13.12625 3.92276   -62.51734 1.000 18.83741 ? 383 VAL B CB  1 
ATOM   7134 C  CG1 . VAL B  1 384 ? 13.75581 4.67689   -63.67937 1.000 20.96800 ? 383 VAL B CG1 1 
ATOM   7135 C  CG2 . VAL B  1 384 ? 12.46506 2.63950   -62.99253 1.000 25.43798 ? 383 VAL B CG2 1 
ATOM   7136 N  N   . LEU B  1 385 ? 15.95185 5.00542   -60.51369 1.000 20.22604 ? 384 LEU B N   1 
ATOM   7137 C  CA  . LEU B  1 385 ? 16.48830 6.20762   -59.89021 1.000 21.56305 ? 384 LEU B CA  1 
ATOM   7138 C  C   . LEU B  1 385 ? 16.46156 7.36112   -60.88329 1.000 16.03193 ? 384 LEU B C   1 
ATOM   7139 O  O   . LEU B  1 385 ? 16.89339 7.21758   -62.03073 1.000 15.19694 ? 384 LEU B O   1 
ATOM   7140 C  CB  . LEU B  1 385 ? 17.90609 5.96122   -59.38122 1.000 18.52680 ? 384 LEU B CB  1 
ATOM   7141 C  CG  . LEU B  1 385 ? 17.96664 5.00281   -58.18979 1.000 20.33943 ? 384 LEU B CG  1 
ATOM   7142 C  CD1 . LEU B  1 385 ? 18.25332 3.57653   -58.64353 1.000 25.78774 ? 384 LEU B CD1 1 
ATOM   7143 C  CD2 . LEU B  1 385 ? 18.98268 5.47061   -57.16394 1.000 24.25356 ? 384 LEU B CD2 1 
ATOM   7144 N  N   . LEU B  1 386 ? 15.94369 8.50524   -60.44321 1.000 18.77872 ? 385 LEU B N   1 
ATOM   7145 C  CA  . LEU B  1 386 ? 15.66052 9.61802   -61.33472 1.000 21.11689 ? 385 LEU B CA  1 
ATOM   7146 C  C   . LEU B  1 386 ? 16.15879 10.92776  -60.74268 1.000 18.05618 ? 385 LEU B C   1 
ATOM   7147 O  O   . LEU B  1 386 ? 16.26587 11.08184  -59.52252 1.000 14.18556 ? 385 LEU B O   1 
ATOM   7148 C  CB  . LEU B  1 386 ? 14.15654 9.72968   -61.61946 1.000 15.83330 ? 385 LEU B CB  1 
ATOM   7149 C  CG  . LEU B  1 386 ? 13.50173 8.53693   -62.31353 1.000 15.64833 ? 385 LEU B CG  1 
ATOM   7150 C  CD1 . LEU B  1 386 ? 11.99647 8.73068   -62.40011 1.000 16.45210 ? 385 LEU B CD1 1 
ATOM   7151 C  CD2 . LEU B  1 386 ? 14.10270 8.33985   -63.69557 1.000 18.81346 ? 385 LEU B CD2 1 
ATOM   7152 N  N   . LEU B  1 387 ? 16.46530 11.86802  -61.63282 1.000 15.05756 ? 386 LEU B N   1 
ATOM   7153 C  CA  . LEU B  1 387 ? 16.73723 13.25252  -61.27227 1.000 12.92329 ? 386 LEU B CA  1 
ATOM   7154 C  C   . LEU B  1 387 ? 15.48564 14.06692  -61.57123 1.000 17.96819 ? 386 LEU B C   1 
ATOM   7155 O  O   . LEU B  1 387 ? 14.98197 14.03884  -62.69993 1.000 17.49991 ? 386 LEU B O   1 
ATOM   7156 C  CB  . LEU B  1 387 ? 17.93261 13.80117  -62.05082 1.000 15.98615 ? 386 LEU B CB  1 
ATOM   7157 C  CG  . LEU B  1 387 ? 19.25427 13.03718  -61.95424 1.000 19.09565 ? 386 LEU B CG  1 
ATOM   7158 C  CD1 . LEU B  1 387 ? 20.28134 13.62684  -62.90791 1.000 13.14263 ? 386 LEU B CD1 1 
ATOM   7159 C  CD2 . LEU B  1 387 ? 19.77436 13.05408  -60.53006 1.000 15.59982 ? 386 LEU B CD2 1 
ATOM   7160 N  N   . ASN B  1 388 ? 14.98148 14.77826  -60.56066 1.000 21.06665 ? 387 ASN B N   1 
ATOM   7161 C  CA  . ASN B  1 388 ? 13.74511 15.55340  -60.67843 1.000 15.23022 ? 387 ASN B CA  1 
ATOM   7162 C  C   . ASN B  1 388 ? 12.57180 14.68695  -61.12584 1.000 15.37188 ? 387 ASN B C   1 
ATOM   7163 O  O   . ASN B  1 388 ? 11.66390 15.16708  -61.80868 1.000 14.41768 ? 387 ASN B O   1 
ATOM   7164 C  CB  . ASN B  1 388 ? 13.91573 16.74169  -61.63025 1.000 19.51168 ? 387 ASN B CB  1 
ATOM   7165 C  CG  . ASN B  1 388 ? 14.52549 17.94802  -60.95203 1.000 23.56303 ? 387 ASN B CG  1 
ATOM   7166 O  OD1 . ASN B  1 388 ? 14.30706 18.18007  -59.76301 1.000 28.96708 ? 387 ASN B OD1 1 
ATOM   7167 N  ND2 . ASN B  1 388 ? 15.29151 18.72817  -61.70593 1.000 23.37292 ? 387 ASN B ND2 1 
ATOM   7168 N  N   . ASN B  1 389 ? 12.59067 13.40388  -60.75187 1.000 15.35591 ? 388 ASN B N   1 
ATOM   7169 C  CA  . ASN B  1 389 ? 11.52950 12.45739  -61.10672 1.000 16.97893 ? 388 ASN B CA  1 
ATOM   7170 C  C   . ASN B  1 389 ? 11.27147 12.44950  -62.61269 1.000 21.75706 ? 388 ASN B C   1 
ATOM   7171 O  O   . ASN B  1 389 ? 10.15324 12.20129  -63.06869 1.000 20.39503 ? 388 ASN B O   1 
ATOM   7172 C  CB  . ASN B  1 389 ? 10.24218 12.76515  -60.33572 1.000 21.83276 ? 388 ASN B CB  1 
ATOM   7173 C  CG  . ASN B  1 389 ? 9.26975  11.60150  -60.32964 1.000 27.29143 ? 388 ASN B CG  1 
ATOM   7174 O  OD1 . ASN B  1 389 ? 9.67376  10.43845  -60.31178 1.000 28.98494 ? 388 ASN B OD1 1 
ATOM   7175 N  ND2 . ASN B  1 389 ? 7.97886  11.91096  -60.35094 1.000 19.62439 ? 388 ASN B ND2 1 
ATOM   7176 N  N   . THR B  1 390 ? 12.31140 12.72198  -63.39650 1.000 19.91699 ? 389 THR B N   1 
ATOM   7177 C  CA  . THR B  1 390 ? 12.19004 12.92467  -64.83250 1.000 16.80301 ? 389 THR B CA  1 
ATOM   7178 C  C   . THR B  1 390 ? 13.11957 11.96435  -65.55960 1.000 21.66334 ? 389 THR B C   1 
ATOM   7179 O  O   . THR B  1 390 ? 14.29353 11.83635  -65.19630 1.000 22.77307 ? 389 THR B O   1 
ATOM   7180 C  CB  . THR B  1 390 ? 12.51824 14.37509  -65.20205 1.000 20.73104 ? 389 THR B CB  1 
ATOM   7181 O  OG1 . THR B  1 390 ? 11.66189 15.25994  -64.46963 1.000 15.33877 ? 389 THR B OG1 1 
ATOM   7182 C  CG2 . THR B  1 390 ? 12.31657 14.61003  -66.68234 1.000 21.82579 ? 389 THR B CG2 1 
ATOM   7183 N  N   . LYS B  1 391 ? 12.59176 11.29125  -66.57949 1.000 31.12416 ? 390 LYS B N   1 
ATOM   7184 C  CA  . LYS B  1 391 ? 13.37700 10.33092  -67.33915 1.000 27.75649 ? 390 LYS B CA  1 
ATOM   7185 C  C   . LYS B  1 391 ? 14.36178 11.04410  -68.26224 1.000 24.33930 ? 390 LYS B C   1 
ATOM   7186 O  O   . LYS B  1 391 ? 14.25169 12.24292  -68.53491 1.000 27.19515 ? 390 LYS B O   1 
ATOM   7187 C  CB  . LYS B  1 391 ? 12.46366 9.41431   -68.15790 1.000 25.40428 ? 390 LYS B CB  1 
ATOM   7188 C  CG  . LYS B  1 391 ? 11.90921 8.21904   -67.38990 1.000 25.36473 ? 390 LYS B CG  1 
ATOM   7189 C  CD  . LYS B  1 391 ? 12.91559 7.07311   -67.32803 1.000 43.83877 ? 390 LYS B CD  1 
ATOM   7190 C  CE  . LYS B  1 391 ? 12.55970 5.96520   -68.31833 1.000 50.82815 ? 390 LYS B CE  1 
ATOM   7191 N  NZ  . LYS B  1 391 ? 13.61968 4.91610   -68.39892 1.000 37.94167 ? 390 LYS B NZ  1 
ATOM   7192 N  N   . TRP B  1 392 ? 15.34085 10.27672  -68.74593 1.000 24.41095 ? 391 TRP B N   1 
ATOM   7193 C  CA  . TRP B  1 392 ? 16.31733 10.81200  -69.68832 1.000 23.72278 ? 391 TRP B CA  1 
ATOM   7194 C  C   . TRP B  1 392 ? 15.67965 11.14870  -71.03054 1.000 34.40166 ? 391 TRP B C   1 
ATOM   7195 O  O   . TRP B  1 392 ? 16.11274 12.09415  -71.70003 1.000 31.99596 ? 391 TRP B O   1 
ATOM   7196 C  CB  . TRP B  1 392 ? 17.45957 9.81051   -69.86533 1.000 22.74245 ? 391 TRP B CB  1 
ATOM   7197 C  CG  . TRP B  1 392 ? 18.25365 9.98286   -71.12388 1.000 25.19503 ? 391 TRP B CG  1 
ATOM   7198 C  CD1 . TRP B  1 392 ? 18.07483 9.31752   -72.30156 1.000 21.94467 ? 391 TRP B CD1 1 
ATOM   7199 C  CD2 . TRP B  1 392 ? 19.36225 10.86792  -71.32791 1.000 21.78202 ? 391 TRP B CD2 1 
ATOM   7200 N  NE1 . TRP B  1 392 ? 18.99855 9.73718   -73.22773 1.000 21.53050 ? 391 TRP B NE1 1 
ATOM   7201 C  CE2 . TRP B  1 392 ? 19.80100 10.68816  -72.65462 1.000 19.11550 ? 391 TRP B CE2 1 
ATOM   7202 C  CE3 . TRP B  1 392 ? 20.02378 11.79647  -70.51903 1.000 22.38991 ? 391 TRP B CE3 1 
ATOM   7203 C  CZ2 . TRP B  1 392 ? 20.86970 11.40158  -73.19016 1.000 15.75485 ? 391 TRP B CZ2 1 
ATOM   7204 C  CZ3 . TRP B  1 392 ? 21.08504 12.50433  -71.05308 1.000 21.08097 ? 391 TRP B CZ3 1 
ATOM   7205 C  CH2 . TRP B  1 392 ? 21.49712 12.30323  -72.37574 1.000 20.23510 ? 391 TRP B CH2 1 
ATOM   7206 N  N   . HIS B  1 393 ? 14.64992 10.39601  -71.43370 1.000 40.90771 ? 392 HIS B N   1 
ATOM   7207 C  CA  . HIS B  1 393 ? 13.96945 10.66197  -72.69923 1.000 34.95692 ? 392 HIS B CA  1 
ATOM   7208 C  C   . HIS B  1 393 ? 13.36942 12.06200  -72.73765 1.000 31.00496 ? 392 HIS B C   1 
ATOM   7209 O  O   . HIS B  1 393 ? 13.20125 12.63724  -73.81973 1.000 30.75304 ? 392 HIS B O   1 
ATOM   7210 C  CB  . HIS B  1 393 ? 12.85547 9.63445   -72.93160 1.000 52.05422 ? 392 HIS B CB  1 
ATOM   7211 C  CG  . HIS B  1 393 ? 13.31619 8.20794   -72.93173 1.000 61.43172 ? 392 HIS B CG  1 
ATOM   7212 N  ND1 . HIS B  1 393 ? 13.10762 7.36072   -73.99973 1.000 56.38038 ? 392 HIS B ND1 1 
ATOM   7213 C  CD2 . HIS B  1 393 ? 13.95117 7.47256   -71.98808 1.000 50.82646 ? 392 HIS B CD2 1 
ATOM   7214 C  CE1 . HIS B  1 393 ? 13.60430 6.16932   -73.71861 1.000 43.54208 ? 392 HIS B CE1 1 
ATOM   7215 N  NE2 . HIS B  1 393 ? 14.12254 6.21073   -72.50434 1.000 56.13479 ? 392 HIS B NE2 1 
ATOM   7216 N  N   . GLU B  1 394 ? 13.04449 12.62246  -71.57706 1.000 31.71907 ? 393 GLU B N   1 
ATOM   7217 C  CA  . GLU B  1 394 ? 12.20133 13.80039  -71.50795 1.000 27.58275 ? 393 GLU B CA  1 
ATOM   7218 C  C   . GLU B  1 394 ? 12.96536 15.05794  -71.92376 1.000 23.74625 ? 393 GLU B C   1 
ATOM   7219 O  O   . GLU B  1 394 ? 14.19787 15.07461  -71.93412 1.000 23.36358 ? 393 GLU B O   1 
ATOM   7220 C  CB  . GLU B  1 394 ? 11.65058 13.94736  -70.09309 1.000 30.24321 ? 393 GLU B CB  1 
ATOM   7221 C  CG  . GLU B  1 394 ? 11.17276 12.63826  -69.48901 1.000 34.38151 ? 393 GLU B CG  1 
ATOM   7222 C  CD  . GLU B  1 394 ? 9.78873  12.74593  -68.88681 1.000 38.22804 ? 393 GLU B CD  1 
ATOM   7223 O  OE1 . GLU B  1 394 ? 8.95408  13.48996  -69.44588 1.000 35.66186 ? 393 GLU B OE1 1 
ATOM   7224 O  OE2 . GLU B  1 394 ? 9.53744  12.08768  -67.85441 1.000 36.18719 ? 393 GLU B OE2 1 
ATOM   7225 N  N   . PRO B  1 395 ? 12.24722 16.12554  -72.27790 1.000 25.99047 ? 394 PRO B N   1 
ATOM   7226 C  CA  . PRO B  1 395 ? 12.91362 17.34696  -72.74452 1.000 21.54928 ? 394 PRO B CA  1 
ATOM   7227 C  C   . PRO B  1 395 ? 13.81266 17.95631  -71.68025 1.000 21.88393 ? 394 PRO B C   1 
ATOM   7228 O  O   . PRO B  1 395 ? 13.61705 17.77217  -70.47676 1.000 31.73048 ? 394 PRO B O   1 
ATOM   7229 C  CB  . PRO B  1 395 ? 11.74571 18.28148  -73.07855 1.000 20.75825 ? 394 PRO B CB  1 
ATOM   7230 C  CG  . PRO B  1 395 ? 10.59427 17.37386  -73.30902 1.000 21.72542 ? 394 PRO B CG  1 
ATOM   7231 C  CD  . PRO B  1 395 ? 10.78181 16.22374  -72.39174 1.000 26.01643 ? 394 PRO B CD  1 
ATOM   7232 N  N   . VAL B  1 396 ? 14.80528 18.71337  -72.14936 1.000 18.61005 ? 395 VAL B N   1 
ATOM   7233 C  CA  . VAL B  1 396 ? 15.80911 19.27781  -71.25653 1.000 17.94903 ? 395 VAL B CA  1 
ATOM   7234 C  C   . VAL B  1 396 ? 15.18691 20.37951  -70.40820 1.000 19.65423 ? 395 VAL B C   1 
ATOM   7235 O  O   . VAL B  1 396 ? 14.36397 21.17368  -70.88461 1.000 19.71904 ? 395 VAL B O   1 
ATOM   7236 C  CB  . VAL B  1 396 ? 17.01563 19.79180  -72.06457 1.000 11.80770 ? 395 VAL B CB  1 
ATOM   7237 C  CG1 . VAL B  1 396 ? 16.60002 20.90139  -73.02131 1.000 16.12509 ? 395 VAL B CG1 1 
ATOM   7238 C  CG2 . VAL B  1 396 ? 18.12767 20.25647  -71.13926 1.000 13.46837 ? 395 VAL B CG2 1 
ATOM   7239 N  N   . THR B  1 397 ? 15.55951 20.41316  -69.13167 1.000 21.12644 ? 396 THR B N   1 
ATOM   7240 C  CA  . THR B  1 397 ? 15.08086 21.41958  -68.19574 1.000 15.15115 ? 396 THR B CA  1 
ATOM   7241 C  C   . THR B  1 397 ? 16.19442 22.22709  -67.55291 1.000 15.65855 ? 396 THR B C   1 
ATOM   7242 O  O   . THR B  1 397 ? 15.97047 23.38775  -67.20352 1.000 20.14557 ? 396 THR B O   1 
ATOM   7243 C  CB  . THR B  1 397 ? 14.24626 20.76759  -67.08250 1.000 13.87069 ? 396 THR B CB  1 
ATOM   7244 O  OG1 . THR B  1 397 ? 15.05650 19.82627  -66.36603 1.000 17.88234 ? 396 THR B OG1 1 
ATOM   7245 C  CG2 . THR B  1 397 ? 13.03885 20.05166  -67.66927 1.000 12.39474 ? 396 THR B CG2 1 
ATOM   7246 N  N   . GLU B  1 398 ? 17.37972 21.64713  -67.38074 1.000 17.96330 ? 397 GLU B N   1 
ATOM   7247 C  CA  . GLU B  1 398 ? 18.52910 22.36371  -66.83212 1.000 14.83329 ? 397 GLU B CA  1 
ATOM   7248 C  C   . GLU B  1 398 ? 19.18867 23.11958  -67.97622 1.000 20.37579 ? 397 GLU B C   1 
ATOM   7249 O  O   . GLU B  1 398 ? 20.06622 22.60420  -68.67206 1.000 17.64512 ? 397 GLU B O   1 
ATOM   7250 C  CB  . GLU B  1 398 ? 19.49717 21.40316  -66.15245 1.000 10.72208 ? 397 GLU B CB  1 
ATOM   7251 C  CG  . GLU B  1 398 ? 19.03690 20.92033  -64.78364 1.000 12.72837 ? 397 GLU B CG  1 
ATOM   7252 C  CD  . GLU B  1 398 ? 17.76862 20.08847  -64.84736 1.000 16.88772 ? 397 GLU B CD  1 
ATOM   7253 O  OE1 . GLU B  1 398 ? 17.81780 18.96667  -65.39247 1.000 17.14159 ? 397 GLU B OE1 1 
ATOM   7254 O  OE2 . GLU B  1 398 ? 16.71881 20.56500  -64.36642 1.000 14.97552 ? 397 GLU B OE2 1 
ATOM   7255 N  N   . THR B  1 399 ? 18.75164 24.36649  -68.17635 1.000 21.01152 ? 398 THR B N   1 
ATOM   7256 C  CA  . THR B  1 399 ? 19.20540 25.20883  -69.28105 1.000 19.11935 ? 398 THR B CA  1 
ATOM   7257 C  C   . THR B  1 399 ? 19.81436 26.49168  -68.72527 1.000 18.59720 ? 398 THR B C   1 
ATOM   7258 O  O   . THR B  1 399 ? 19.19285 27.56275  -68.78685 1.000 20.08728 ? 398 THR B O   1 
ATOM   7259 C  CB  . THR B  1 399 ? 18.06162 25.52916  -70.24245 1.000 16.21871 ? 398 THR B CB  1 
ATOM   7260 O  OG1 . THR B  1 399 ? 16.97208 26.10087  -69.51003 1.000 20.90092 ? 398 THR B OG1 1 
ATOM   7261 C  CG2 . THR B  1 399 ? 17.58630 24.26937  -70.94438 1.000 19.81955 ? 398 THR B CG2 1 
ATOM   7262 N  N   . PRO B  1 400 ? 21.02891 26.42742  -68.18751 1.000 14.95917 ? 399 PRO B N   1 
ATOM   7263 C  CA  . PRO B  1 400 ? 21.71373 27.65125  -67.76691 1.000 15.19765 ? 399 PRO B CA  1 
ATOM   7264 C  C   . PRO B  1 400 ? 22.23702 28.43515  -68.95744 1.000 21.37569 ? 399 PRO B C   1 
ATOM   7265 O  O   . PRO B  1 400 ? 22.51330 27.88606  -70.02699 1.000 19.57778 ? 399 PRO B O   1 
ATOM   7266 C  CB  . PRO B  1 400 ? 22.86856 27.13064  -66.90426 1.000 16.75818 ? 399 PRO B CB  1 
ATOM   7267 C  CG  . PRO B  1 400 ? 23.14601 25.77866  -67.44245 1.000 19.56642 ? 399 PRO B CG  1 
ATOM   7268 C  CD  . PRO B  1 400 ? 21.81876 25.22250  -67.88295 1.000 21.72149 ? 399 PRO B CD  1 
ATOM   7269 N  N   . ALA B  1 401 ? 22.37089 29.74059  -68.75418 1.000 20.06519 ? 400 ALA B N   1 
ATOM   7270 C  CA  . ALA B  1 401 ? 22.88563 30.62782  -69.78299 1.000 17.48498 ? 400 ALA B CA  1 
ATOM   7271 C  C   . ALA B  1 401 ? 24.40605 30.67747  -69.72677 1.000 20.02790 ? 400 ALA B C   1 
ATOM   7272 O  O   . ALA B  1 401 ? 25.01346 30.54231  -68.66099 1.000 17.01062 ? 400 ALA B O   1 
ATOM   7273 C  CB  . ALA B  1 401 ? 22.30869 32.03398  -69.62406 1.000 15.40207 ? 400 ALA B CB  1 
ATOM   7274 N  N   . LEU B  1 402 ? 25.01487 30.86841  -70.89454 1.000 23.58201 ? 401 LEU B N   1 
ATOM   7275 C  CA  . LEU B  1 402 ? 26.46702 30.91925  -70.99613 1.000 18.93445 ? 401 LEU B CA  1 
ATOM   7276 C  C   . LEU B  1 402 ? 27.01796 32.05886  -70.14936 1.000 18.12902 ? 401 LEU B C   1 
ATOM   7277 O  O   . LEU B  1 402 ? 26.67098 33.22533  -70.35802 1.000 21.05329 ? 401 LEU B O   1 
ATOM   7278 C  CB  . LEU B  1 402 ? 26.87795 31.08797  -72.45836 1.000 24.12006 ? 401 LEU B CB  1 
ATOM   7279 C  CG  . LEU B  1 402 ? 28.37521 31.13307  -72.77192 1.000 25.70564 ? 401 LEU B CG  1 
ATOM   7280 C  CD1 . LEU B  1 402 ? 29.04820 29.81955  -72.40120 1.000 19.21324 ? 401 LEU B CD1 1 
ATOM   7281 C  CD2 . LEU B  1 402 ? 28.60130 31.45791  -74.24065 1.000 18.21838 ? 401 LEU B CD2 1 
ATOM   7282 N  N   . GLY B  1 403 ? 27.87039 31.71702  -69.18680 1.000 18.27895 ? 402 GLY B N   1 
ATOM   7283 C  CA  . GLY B  1 403 ? 28.49087 32.69962  -68.32605 1.000 18.37858 ? 402 GLY B CA  1 
ATOM   7284 C  C   . GLY B  1 403 ? 27.72634 33.03367  -67.06462 1.000 15.05727 ? 402 GLY B C   1 
ATOM   7285 O  O   . GLY B  1 403 ? 28.20541 33.85391  -66.27081 1.000 17.58714 ? 402 GLY B O   1 
ATOM   7286 N  N   . SER B  1 404 ? 26.56245 32.42809  -66.84770 1.000 16.11050 ? 403 SER B N   1 
ATOM   7287 C  CA  . SER B  1 404 ? 25.75554 32.71122  -65.67021 1.000 20.29046 ? 403 SER B CA  1 
ATOM   7288 C  C   . SER B  1 404 ? 26.20813 31.85681  -64.49466 1.000 19.86108 ? 403 SER B C   1 
ATOM   7289 O  O   . SER B  1 404 ? 26.62270 30.70696  -64.66665 1.000 17.00104 ? 403 SER B O   1 
ATOM   7290 C  CB  . SER B  1 404 ? 24.27405 32.45927  -65.95569 1.000 19.61535 ? 403 SER B CB  1 
ATOM   7291 O  OG  . SER B  1 404 ? 24.03791 31.09458  -66.24959 1.000 21.61881 ? 403 SER B OG  1 
ATOM   7292 N  N   . THR B  1 405 ? 26.12922 32.43164  -63.29929 1.000 20.41788 ? 404 THR B N   1 
ATOM   7293 C  CA  . THR B  1 405 ? 26.42777 31.72499  -62.06252 1.000 17.93075 ? 404 THR B CA  1 
ATOM   7294 C  C   . THR B  1 405 ? 25.12181 31.28829  -61.41339 1.000 19.14922 ? 404 THR B C   1 
ATOM   7295 O  O   . THR B  1 405 ? 24.19791 32.09494  -61.26322 1.000 20.78244 ? 404 THR B O   1 
ATOM   7296 C  CB  . THR B  1 405 ? 27.22837 32.61031  -61.10621 1.000 20.85922 ? 404 THR B CB  1 
ATOM   7297 O  OG1 . THR B  1 405 ? 28.50242 32.91263  -61.68815 1.000 21.23902 ? 404 THR B OG1 1 
ATOM   7298 C  CG2 . THR B  1 405 ? 27.43947 31.90807  -59.77386 1.000 18.39912 ? 404 THR B CG2 1 
ATOM   7299 N  N   . GLU B  1 406 ? 25.04527 30.01438  -61.03789 1.000 11.82972 ? 405 GLU B N   1 
ATOM   7300 C  CA  . GLU B  1 406 ? 23.83926 29.44956  -60.45530 1.000 12.04788 ? 405 GLU B CA  1 
ATOM   7301 C  C   . GLU B  1 406 ? 24.17122 28.77228  -59.13471 1.000 11.65473 ? 405 GLU B C   1 
ATOM   7302 O  O   . GLU B  1 406 ? 25.31503 28.39300  -58.87791 1.000 15.11040 ? 405 GLU B O   1 
ATOM   7303 C  CB  . GLU B  1 406 ? 23.17648 28.43894  -61.40033 1.000 12.84486 ? 405 GLU B CB  1 
ATOM   7304 C  CG  . GLU B  1 406 ? 22.91989 28.97022  -62.79660 1.000 13.77180 ? 405 GLU B CG  1 
ATOM   7305 C  CD  . GLU B  1 406 ? 21.99691 28.07632  -63.59678 1.000 15.46330 ? 405 GLU B CD  1 
ATOM   7306 O  OE1 . GLU B  1 406 ? 21.88722 26.87825  -63.25963 1.000 17.56949 ? 405 GLU B OE1 1 
ATOM   7307 O  OE2 . GLU B  1 406 ? 21.37358 28.57491  -64.55769 1.000 15.78517 ? 405 GLU B OE2 1 
ATOM   7308 N  N   . ILE B  1 407 ? 23.15045 28.62921  -58.29438 1.000 13.18092 ? 406 ILE B N   1 
ATOM   7309 C  CA  . ILE B  1 407 ? 23.23573 27.85420  -57.06171 1.000 13.45012 ? 406 ILE B CA  1 
ATOM   7310 C  C   . ILE B  1 407 ? 22.24658 26.70534  -57.18749 1.000 15.23405 ? 406 ILE B C   1 
ATOM   7311 O  O   . ILE B  1 407 ? 21.02784 26.92275  -57.17319 1.000 16.05641 ? 406 ILE B O   1 
ATOM   7312 C  CB  . ILE B  1 407 ? 22.94006 28.69773  -55.81479 1.000 13.85930 ? 406 ILE B CB  1 
ATOM   7313 C  CG1 . ILE B  1 407 ? 24.02717 29.75092  -55.60255 1.000 16.23434 ? 406 ILE B CG1 1 
ATOM   7314 C  CG2 . ILE B  1 407 ? 22.82838 27.80571  -54.58717 1.000 14.38421 ? 406 ILE B CG2 1 
ATOM   7315 C  CD1 . ILE B  1 407 ? 23.82178 30.58568  -54.35535 1.000 11.66385 ? 406 ILE B CD1 1 
ATOM   7316 N  N   . TRP B  1 408 ? 22.76297 25.48687  -57.32101 1.000 12.36537 ? 407 TRP B N   1 
ATOM   7317 C  CA  . TRP B  1 408 ? 21.92449 24.29884  -57.39027 1.000 12.46917 ? 407 TRP B CA  1 
ATOM   7318 C  C   . TRP B  1 408 ? 21.70761 23.74068  -55.99102 1.000 13.71086 ? 407 TRP B C   1 
ATOM   7319 O  O   . TRP B  1 408 ? 22.66992 23.51041  -55.25159 1.000 15.14369 ? 407 TRP B O   1 
ATOM   7320 C  CB  . TRP B  1 408 ? 22.55626 23.22519  -58.27620 1.000 12.22681 ? 407 TRP B CB  1 
ATOM   7321 C  CG  . TRP B  1 408 ? 22.56640 23.53200  -59.73746 1.000 11.72319 ? 407 TRP B CG  1 
ATOM   7322 C  CD1 . TRP B  1 408 ? 22.53617 24.76334  -60.32266 1.000 12.02511 ? 407 TRP B CD1 1 
ATOM   7323 C  CD2 . TRP B  1 408 ? 22.60506 22.57941  -60.80658 1.000 10.71690 ? 407 TRP B CD2 1 
ATOM   7324 N  NE1 . TRP B  1 408 ? 22.55789 24.63647  -61.69157 1.000 11.89291 ? 407 TRP B NE1 1 
ATOM   7325 C  CE2 . TRP B  1 408 ? 22.59908 23.30494  -62.01320 1.000 11.14335 ? 407 TRP B CE2 1 
ATOM   7326 C  CE3 . TRP B  1 408 ? 22.64476 21.18258  -60.85923 1.000 8.17510  ? 407 TRP B CE3 1 
ATOM   7327 C  CZ2 . TRP B  1 408 ? 22.63152 22.68126  -63.25838 1.000 9.28474  ? 407 TRP B CZ2 1 
ATOM   7328 C  CZ3 . TRP B  1 408 ? 22.67519 20.56599  -62.09456 1.000 9.75269  ? 407 TRP B CZ3 1 
ATOM   7329 C  CH2 . TRP B  1 408 ? 22.66847 21.31432  -63.27772 1.000 9.74945  ? 407 TRP B CH2 1 
ATOM   7330 N  N   . SER B  1 409 ? 20.44632 23.52431  -55.63303 1.000 15.45582 ? 408 SER B N   1 
ATOM   7331 C  CA  . SER B  1 409 ? 20.08657 22.83082  -54.40193 1.000 18.71206 ? 408 SER B CA  1 
ATOM   7332 C  C   . SER B  1 409 ? 19.71449 21.39973  -54.77080 1.000 17.16861 ? 408 SER B C   1 
ATOM   7333 O  O   . SER B  1 409 ? 18.69283 21.16555  -55.42474 1.000 14.19370 ? 408 SER B O   1 
ATOM   7334 C  CB  . SER B  1 409 ? 18.93974 23.53847  -53.68375 1.000 15.89706 ? 408 SER B CB  1 
ATOM   7335 O  OG  . SER B  1 409 ? 19.33627 24.82589  -53.24211 1.000 15.24441 ? 408 SER B OG  1 
ATOM   7336 N  N   . ILE B  1 410 ? 20.55086 20.44980  -54.36722 1.000 15.37501 ? 409 ILE B N   1 
ATOM   7337 C  CA  . ILE B  1 410 ? 20.35857 19.04028  -54.68405 1.000 16.76597 ? 409 ILE B CA  1 
ATOM   7338 C  C   . ILE B  1 410 ? 19.70670 18.38345  -53.47400 1.000 14.63222 ? 409 ILE B C   1 
ATOM   7339 O  O   . ILE B  1 410 ? 20.31867 18.27680  -52.40626 1.000 15.74210 ? 409 ILE B O   1 
ATOM   7340 C  CB  . ILE B  1 410 ? 21.68276 18.36227  -55.05585 1.000 18.10426 ? 409 ILE B CB  1 
ATOM   7341 C  CG1 . ILE B  1 410 ? 22.42560 19.20346  -56.09662 1.000 15.83581 ? 409 ILE B CG1 1 
ATOM   7342 C  CG2 . ILE B  1 410 ? 21.43152 16.96076  -55.59045 1.000 14.70633 ? 409 ILE B CG2 1 
ATOM   7343 C  CD1 . ILE B  1 410 ? 23.77971 18.64773  -56.48568 1.000 14.70491 ? 409 ILE B CD1 1 
ATOM   7344 N  N   . ILE B  1 411 ? 18.46575 17.93914  -53.64133 1.000 13.25059 ? 410 ILE B N   1 
ATOM   7345 C  CA  . ILE B  1 411 ? 17.63755 17.44887  -52.54574 1.000 14.49431 ? 410 ILE B CA  1 
ATOM   7346 C  C   . ILE B  1 411 ? 17.62291 15.92604  -52.60157 1.000 16.72382 ? 410 ILE B C   1 
ATOM   7347 O  O   . ILE B  1 411 ? 17.00991 15.33365  -53.49607 1.000 16.67138 ? 410 ILE B O   1 
ATOM   7348 C  CB  . ILE B  1 411 ? 16.21792 18.02290  -52.62553 1.000 14.85185 ? 410 ILE B CB  1 
ATOM   7349 C  CG1 . ILE B  1 411 ? 16.26778 19.55148  -52.68212 1.000 17.67531 ? 410 ILE B CG1 1 
ATOM   7350 C  CG2 . ILE B  1 411 ? 15.39300 17.56035  -51.44559 1.000 18.30354 ? 410 ILE B CG2 1 
ATOM   7351 C  CD1 . ILE B  1 411 ? 14.92361 20.19905  -52.92790 1.000 16.67049 ? 410 ILE B CD1 1 
ATOM   7352 N  N   . ASN B  1 412 ? 18.28471 15.28461  -51.63939 1.000 13.49474 ? 411 ASN B N   1 
ATOM   7353 C  CA  . ASN B  1 412 ? 18.38808 13.82667  -51.59150 1.000 17.08963 ? 411 ASN B CA  1 
ATOM   7354 C  C   . ASN B  1 412 ? 17.37061 13.29672  -50.58782 1.000 22.62167 ? 411 ASN B C   1 
ATOM   7355 O  O   . ASN B  1 412 ? 17.58744 13.35657  -49.37489 1.000 16.99903 ? 411 ASN B O   1 
ATOM   7356 C  CB  . ASN B  1 412 ? 19.80267 13.38937  -51.22550 1.000 13.37510 ? 411 ASN B CB  1 
ATOM   7357 C  CG  . ASN B  1 412 ? 19.98082 11.88044  -51.27961 1.000 18.78727 ? 411 ASN B CG  1 
ATOM   7358 O  OD1 . ASN B  1 412 ? 19.08828 11.15207  -51.71537 1.000 23.65701 ? 411 ASN B OD1 1 
ATOM   7359 N  ND2 . ASN B  1 412 ? 21.14266 11.40548  -50.84503 1.000 15.41048 ? 411 ASN B ND2 1 
ATOM   7360 N  N   . ALA B  1 413 ? 16.26201 12.76859  -51.09975 1.000 23.95929 ? 412 ALA B N   1 
ATOM   7361 C  CA  . ALA B  1 413 ? 15.26498 12.09811  -50.27932 1.000 25.67499 ? 412 ALA B CA  1 
ATOM   7362 C  C   . ALA B  1 413 ? 15.51235 10.59881  -50.17205 1.000 30.01782 ? 412 ALA B C   1 
ATOM   7363 O  O   . ALA B  1 413 ? 14.67399 9.88195   -49.61628 1.000 36.64799 ? 412 ALA B O   1 
ATOM   7364 C  CB  . ALA B  1 413 ? 13.86222 12.35708  -50.83457 1.000 27.80242 ? 412 ALA B CB  1 
ATOM   7365 N  N   . GLY B  1 414 ? 16.64131 10.11344  -50.68755 1.000 30.49473 ? 413 GLY B N   1 
ATOM   7366 C  CA  . GLY B  1 414 ? 16.95025 8.70150   -50.65973 1.000 30.81690 ? 413 GLY B CA  1 
ATOM   7367 C  C   . GLY B  1 414 ? 17.59761 8.26145   -49.35940 1.000 27.97569 ? 413 GLY B C   1 
ATOM   7368 O  O   . GLY B  1 414 ? 17.77701 9.02919   -48.41404 1.000 17.70629 ? 413 GLY B O   1 
ATOM   7369 N  N   . ARG B  1 415 ? 17.96536 6.98089   -49.32813 1.000 29.89376 ? 414 ARG B N   1 
ATOM   7370 C  CA  . ARG B  1 415 ? 18.49998 6.36063   -48.12447 1.000 25.50355 ? 414 ARG B CA  1 
ATOM   7371 C  C   . ARG B  1 415 ? 20.01720 6.42819   -48.02777 1.000 23.96837 ? 414 ARG B C   1 
ATOM   7372 O  O   . ARG B  1 415 ? 20.55443 6.33179   -46.91936 1.000 22.73724 ? 414 ARG B O   1 
ATOM   7373 C  CB  . ARG B  1 415 ? 18.05620 4.89639   -48.05023 1.000 31.45121 ? 414 ARG B CB  1 
ATOM   7374 C  CG  . ARG B  1 415 ? 16.61560 4.71383   -47.61113 1.000 42.82259 ? 414 ARG B CG  1 
ATOM   7375 C  CD  . ARG B  1 415 ? 15.95077 3.55261   -48.33328 1.000 49.82912 ? 414 ARG B CD  1 
ATOM   7376 N  NE  . ARG B  1 415 ? 14.63023 3.26339   -47.78655 1.000 62.08329 ? 414 ARG B NE  1 
ATOM   7377 C  CZ  . ARG B  1 415 ? 13.54152 3.97976   -48.03326 1.000 60.57964 ? 414 ARG B CZ  1 
ATOM   7378 N  NH1 . ARG B  1 415 ? 13.57814 5.04847   -48.81302 1.000 50.28892 ? 414 ARG B NH1 1 
ATOM   7379 N  NH2 . ARG B  1 415 ? 12.38756 3.61766   -47.47954 1.000 55.49479 ? 414 ARG B NH2 1 
ATOM   7380 N  N   . ALA B  1 416 ? 20.71874 6.59478   -49.14622 1.000 19.47415 ? 415 ALA B N   1 
ATOM   7381 C  CA  . ALA B  1 416 ? 22.17306 6.56184   -49.16012 1.000 19.12171 ? 415 ALA B CA  1 
ATOM   7382 C  C   . ALA B  1 416 ? 22.71728 7.72355   -49.98106 1.000 19.05111 ? 415 ALA B C   1 
ATOM   7383 O  O   . ALA B  1 416 ? 21.97360 8.47466   -50.61847 1.000 20.12616 ? 415 ALA B O   1 
ATOM   7384 C  CB  . ALA B  1 416 ? 22.69837 5.22920   -49.71349 1.000 16.18373 ? 415 ALA B CB  1 
ATOM   7385 N  N   . ILE B  1 417 ? 24.04551 7.85200   -49.95975 1.000 18.17405 ? 416 ILE B N   1 
ATOM   7386 C  CA  . ILE B  1 417 ? 24.72281 8.94688   -50.64298 1.000 17.54539 ? 416 ILE B CA  1 
ATOM   7387 C  C   . ILE B  1 417 ? 24.56217 8.80273   -52.15082 1.000 14.86504 ? 416 ILE B C   1 
ATOM   7388 O  O   . ILE B  1 417 ? 24.58461 7.69121   -52.69626 1.000 18.37093 ? 416 ILE B O   1 
ATOM   7389 C  CB  . ILE B  1 417 ? 26.20745 8.97839   -50.23679 1.000 11.77273 ? 416 ILE B CB  1 
ATOM   7390 C  CG1 . ILE B  1 417 ? 26.34244 9.25749   -48.73790 1.000 14.15954 ? 416 ILE B CG1 1 
ATOM   7391 C  CG2 . ILE B  1 417 ? 26.97808 10.01260  -51.04138 1.000 9.29584  ? 416 ILE B CG2 1 
ATOM   7392 C  CD1 . ILE B  1 417 ? 27.77335 9.28396   -48.24525 1.000 9.52228  ? 416 ILE B CD1 1 
ATOM   7393 N  N   . HIS B  1 418 ? 24.37958 9.92973   -52.82940 1.000 15.74774 ? 417 HIS B N   1 
ATOM   7394 C  CA  . HIS B  1 418 ? 24.40392 9.98558   -54.29056 1.000 13.67634 ? 417 HIS B CA  1 
ATOM   7395 C  C   . HIS B  1 418 ? 25.54727 10.88696  -54.73352 1.000 14.56128 ? 417 HIS B C   1 
ATOM   7396 O  O   . HIS B  1 418 ? 25.50704 12.10459  -54.47188 1.000 15.75476 ? 417 HIS B O   1 
ATOM   7397 C  CB  . HIS B  1 418 ? 23.07832 10.50380  -54.84741 1.000 12.26051 ? 417 HIS B CB  1 
ATOM   7398 C  CG  . HIS B  1 418 ? 21.93725 9.54763   -54.69526 1.000 15.73400 ? 417 HIS B CG  1 
ATOM   7399 N  ND1 . HIS B  1 418 ? 21.81325 8.40871   -55.46117 1.000 20.33905 ? 417 HIS B ND1 1 
ATOM   7400 C  CD2 . HIS B  1 418 ? 20.85914 9.56932   -53.87651 1.000 18.29174 ? 417 HIS B CD2 1 
ATOM   7401 C  CE1 . HIS B  1 418 ? 20.71273 7.76525   -55.11460 1.000 18.67592 ? 417 HIS B CE1 1 
ATOM   7402 N  NE2 . HIS B  1 418 ? 20.11529 8.44869   -54.15524 1.000 17.63445 ? 417 HIS B NE2 1 
ATOM   7403 N  N   . PRO B  1 419 ? 26.58534 10.35806  -55.38362 1.000 12.35302 ? 418 PRO B N   1 
ATOM   7404 C  CA  . PRO B  1 419 ? 27.64489 11.22950  -55.91000 1.000 15.62202 ? 418 PRO B CA  1 
ATOM   7405 C  C   . PRO B  1 419 ? 27.23137 11.91172  -57.20503 1.000 14.51544 ? 418 PRO B C   1 
ATOM   7406 O  O   . PRO B  1 419 ? 27.40520 11.35617  -58.29433 1.000 12.93265 ? 418 PRO B O   1 
ATOM   7407 C  CB  . PRO B  1 419 ? 28.81495 10.26299  -56.12635 1.000 17.00802 ? 418 PRO B CB  1 
ATOM   7408 C  CG  . PRO B  1 419 ? 28.15912 8.94835   -56.38495 1.000 16.00106 ? 418 PRO B CG  1 
ATOM   7409 C  CD  . PRO B  1 419 ? 26.90693 8.93052   -55.54616 1.000 14.87713 ? 418 PRO B CD  1 
ATOM   7410 N  N   . ILE B  1 420 ? 26.68263 13.11726  -57.09673 1.000 15.80962 ? 419 ILE B N   1 
ATOM   7411 C  CA  . ILE B  1 420 ? 26.16938 13.83212  -58.26018 1.000 13.33980 ? 419 ILE B CA  1 
ATOM   7412 C  C   . ILE B  1 420 ? 27.32524 14.51037  -58.98232 1.000 12.25261 ? 419 ILE B C   1 
ATOM   7413 O  O   . ILE B  1 420 ? 28.15391 15.18633  -58.36071 1.000 12.67760 ? 419 ILE B O   1 
ATOM   7414 C  CB  . ILE B  1 420 ? 25.09677 14.84985  -57.84246 1.000 9.54712  ? 419 ILE B CB  1 
ATOM   7415 C  CG1 . ILE B  1 420 ? 23.96478 14.14481  -57.09254 1.000 9.42323  ? 419 ILE B CG1 1 
ATOM   7416 C  CG2 . ILE B  1 420 ? 24.55809 15.58817  -59.05829 1.000 10.03656 ? 419 ILE B CG2 1 
ATOM   7417 C  CD1 . ILE B  1 420 ? 23.34087 13.00102  -57.86279 1.000 8.25018  ? 419 ILE B CD1 1 
ATOM   7418 N  N   . HIS B  1 421 ? 27.37784 14.33717  -60.30019 1.000 10.45703 ? 420 HIS B N   1 
ATOM   7419 C  CA  . HIS B  1 421 ? 28.45525 14.85740  -61.12921 1.000 9.00178  ? 420 HIS B CA  1 
ATOM   7420 C  C   . HIS B  1 421 ? 27.87947 15.74040  -62.22708 1.000 11.98305 ? 420 HIS B C   1 
ATOM   7421 O  O   . HIS B  1 421 ? 26.88968 15.37392  -62.87003 1.000 15.08793 ? 420 HIS B O   1 
ATOM   7422 C  CB  . HIS B  1 421 ? 29.27035 13.71196  -61.73918 1.000 12.92349 ? 420 HIS B CB  1 
ATOM   7423 C  CG  . HIS B  1 421 ? 30.15248 14.13324  -62.87265 1.000 14.07487 ? 420 HIS B CG  1 
ATOM   7424 N  ND1 . HIS B  1 421 ? 31.26982 14.92091  -62.69531 1.000 13.14651 ? 420 HIS B ND1 1 
ATOM   7425 C  CD2 . HIS B  1 421 ? 30.07839 13.87884  -64.20030 1.000 11.34933 ? 420 HIS B CD2 1 
ATOM   7426 C  CE1 . HIS B  1 421 ? 31.84622 15.13297  -63.86499 1.000 14.08920 ? 420 HIS B CE1 1 
ATOM   7427 N  NE2 . HIS B  1 421 ? 31.14437 14.50965  -64.79406 1.000 15.56265 ? 420 HIS B NE2 1 
ATOM   7428 N  N   . LEU B  1 422 ? 28.49789 16.89986  -62.43446 1.000 10.54451 ? 421 LEU B N   1 
ATOM   7429 C  CA  . LEU B  1 422 ? 28.14838 17.80867  -63.51720 1.000 10.39525 ? 421 LEU B CA  1 
ATOM   7430 C  C   . LEU B  1 422 ? 29.27896 17.84194  -64.53589 1.000 11.52875 ? 421 LEU B C   1 
ATOM   7431 O  O   . LEU B  1 422 ? 30.45619 17.76037  -64.17165 1.000 11.95291 ? 421 LEU B O   1 
ATOM   7432 C  CB  . LEU B  1 422 ? 27.88284 19.22582  -62.99555 1.000 10.23552 ? 421 LEU B CB  1 
ATOM   7433 C  CG  . LEU B  1 422 ? 26.47762 19.60184  -62.51354 1.000 11.98704 ? 421 LEU B CG  1 
ATOM   7434 C  CD1 . LEU B  1 422 ? 26.04238 18.75682  -61.32313 1.000 9.85941  ? 421 LEU B CD1 1 
ATOM   7435 C  CD2 . LEU B  1 422 ? 26.42102 21.08295  -62.16774 1.000 6.49956  ? 421 LEU B CD2 1 
ATOM   7436 N  N   . HIS B  1 423 ? 28.92131 17.96027  -65.80977 1.000 11.94420 ? 422 HIS B N   1 
ATOM   7437 C  CA  . HIS B  1 423 ? 29.91737 18.04852  -66.86474 1.000 13.44822 ? 422 HIS B CA  1 
ATOM   7438 C  C   . HIS B  1 423 ? 30.35671 19.49649  -67.07117 1.000 13.64264 ? 422 HIS B C   1 
ATOM   7439 O  O   . HIS B  1 423 ? 29.78363 20.43562  -66.51460 1.000 21.35851 ? 422 HIS B O   1 
ATOM   7440 C  CB  . HIS B  1 423 ? 29.37695 17.46537  -68.17089 1.000 13.91140 ? 422 HIS B CB  1 
ATOM   7441 C  CG  . HIS B  1 423 ? 29.33184 15.96908  -68.19339 1.000 15.02732 ? 422 HIS B CG  1 
ATOM   7442 N  ND1 . HIS B  1 423 ? 29.59194 15.23443  -69.33043 1.000 15.82154 ? 422 HIS B ND1 1 
ATOM   7443 C  CD2 . HIS B  1 423 ? 29.05597 15.06944  -67.21966 1.000 16.02938 ? 422 HIS B CD2 1 
ATOM   7444 C  CE1 . HIS B  1 423 ? 29.48269 13.94679  -69.05524 1.000 15.67943 ? 422 HIS B CE1 1 
ATOM   7445 N  NE2 . HIS B  1 423 ? 29.15456 13.81968  -67.78211 1.000 15.90108 ? 422 HIS B NE2 1 
ATOM   7446 N  N   . LEU B  1 424 ? 31.41189 19.65914  -67.87210 1.000 13.58846 ? 423 LEU B N   1 
ATOM   7447 C  CA  . LEU B  1 424 ? 31.93039 20.95727  -68.29733 1.000 16.39017 ? 423 LEU B CA  1 
ATOM   7448 C  C   . LEU B  1 424 ? 32.55412 21.76432  -67.16431 1.000 12.70890 ? 423 LEU B C   1 
ATOM   7449 O  O   . LEU B  1 424 ? 33.69450 22.22351  -67.28304 1.000 17.60913 ? 423 LEU B O   1 
ATOM   7450 C  CB  . LEU B  1 424 ? 30.83009 21.79114  -68.96246 1.000 15.77298 ? 423 LEU B CB  1 
ATOM   7451 C  CG  . LEU B  1 424 ? 31.24097 23.22356  -69.31495 1.000 13.85292 ? 423 LEU B CG  1 
ATOM   7452 C  CD1 . LEU B  1 424 ? 32.24788 23.22152  -70.45478 1.000 17.83123 ? 423 LEU B CD1 1 
ATOM   7453 C  CD2 . LEU B  1 424 ? 30.03289 24.07908  -69.65845 1.000 14.12271 ? 423 LEU B CD2 1 
ATOM   7454 N  N   . VAL B  1 425 ? 31.82567 21.94515  -66.07070 1.000 12.61249 ? 424 VAL B N   1 
ATOM   7455 C  CA  . VAL B  1 425 ? 32.15121 22.95844  -65.08908 1.000 13.21473 ? 424 VAL B CA  1 
ATOM   7456 C  C   . VAL B  1 425 ? 32.88138 22.34077  -63.90204 1.000 18.13792 ? 424 VAL B C   1 
ATOM   7457 O  O   . VAL B  1 425 ? 32.97580 21.12371  -63.75914 1.000 14.77251 ? 424 VAL B O   1 
ATOM   7458 C  CB  . VAL B  1 425 ? 30.88868 23.71621  -64.61721 1.000 13.52280 ? 424 VAL B CB  1 
ATOM   7459 C  CG1 . VAL B  1 425 ? 30.17144 24.34528  -65.80149 1.000 15.56065 ? 424 VAL B CG1 1 
ATOM   7460 C  CG2 . VAL B  1 425 ? 29.96349 22.77578  -63.86139 1.000 9.69847  ? 424 VAL B CG2 1 
ATOM   7461 N  N   . GLN B  1 426 ? 33.42415 23.20410  -63.04553 1.000 13.96332 ? 425 GLN B N   1 
ATOM   7462 C  CA  . GLN B  1 426 ? 33.89831 22.84916  -61.71605 1.000 12.44670 ? 425 GLN B CA  1 
ATOM   7463 C  C   . GLN B  1 426 ? 33.20696 23.78079  -60.73326 1.000 12.84540 ? 425 GLN B C   1 
ATOM   7464 O  O   . GLN B  1 426 ? 33.19225 24.99802  -60.94051 1.000 12.49523 ? 425 GLN B O   1 
ATOM   7465 C  CB  . GLN B  1 426 ? 35.42191 22.97946  -61.60323 1.000 15.07542 ? 425 GLN B CB  1 
ATOM   7466 C  CG  . GLN B  1 426 ? 36.20502 22.06446  -62.53099 1.000 11.13151 ? 425 GLN B CG  1 
ATOM   7467 C  CD  . GLN B  1 426 ? 36.21523 20.62098  -62.06321 1.000 13.71831 ? 425 GLN B CD  1 
ATOM   7468 O  OE1 . GLN B  1 426 ? 36.09405 20.34034  -60.87021 1.000 11.64587 ? 425 GLN B OE1 1 
ATOM   7469 N  NE2 . GLN B  1 426 ? 36.36042 19.69576  -63.00464 1.000 12.70644 ? 425 GLN B NE2 1 
ATOM   7470 N  N   . PHE B  1 427 ? 32.62257 23.21940  -59.68276 1.000 12.16056 ? 426 PHE B N   1 
ATOM   7471 C  CA  . PHE B  1 427 ? 31.80546 23.99233  -58.75730 1.000 12.18750 ? 426 PHE B CA  1 
ATOM   7472 C  C   . PHE B  1 427 ? 32.45368 24.02741  -57.37524 1.000 12.96093 ? 426 PHE B C   1 
ATOM   7473 O  O   . PHE B  1 427 ? 33.48741 23.40400  -57.12656 1.000 13.82282 ? 426 PHE B O   1 
ATOM   7474 C  CB  . PHE B  1 427 ? 30.38326 23.42542  -58.68114 1.000 11.80302 ? 426 PHE B CB  1 
ATOM   7475 C  CG  . PHE B  1 427 ? 30.32269 21.95655  -58.35608 1.000 12.78142 ? 426 PHE B CG  1 
ATOM   7476 C  CD1 . PHE B  1 427 ? 30.49646 21.50716  -57.05578 1.000 9.37708  ? 426 PHE B CD1 1 
ATOM   7477 C  CD2 . PHE B  1 427 ? 30.07073 21.02651  -59.35029 1.000 12.58190 ? 426 PHE B CD2 1 
ATOM   7478 C  CE1 . PHE B  1 427 ? 30.43695 20.15891  -56.75899 1.000 10.30134 ? 426 PHE B CE1 1 
ATOM   7479 C  CE2 . PHE B  1 427 ? 30.00538 19.67706  -59.05669 1.000 9.21679  ? 426 PHE B CE2 1 
ATOM   7480 C  CZ  . PHE B  1 427 ? 30.18952 19.24354  -57.76083 1.000 7.14026  ? 426 PHE B CZ  1 
ATOM   7481 N  N   . LEU B  1 428 ? 31.82022 24.77395  -56.47363 1.000 11.82499 ? 427 LEU B N   1 
ATOM   7482 C  CA  . LEU B  1 428 ? 32.22686 24.86725  -55.07788 1.000 14.37223 ? 427 LEU B CA  1 
ATOM   7483 C  C   . LEU B  1 428 ? 31.05784 24.44867  -54.19804 1.000 16.15786 ? 427 LEU B C   1 
ATOM   7484 O  O   . LEU B  1 428 ? 29.94017 24.95026  -54.36423 1.000 15.88233 ? 427 LEU B O   1 
ATOM   7485 C  CB  . LEU B  1 428 ? 32.67682 26.28916  -54.72184 1.000 10.22167 ? 427 LEU B CB  1 
ATOM   7486 C  CG  . LEU B  1 428 ? 33.86517 26.85336  -55.50259 1.000 13.77320 ? 427 LEU B CG  1 
ATOM   7487 C  CD1 . LEU B  1 428 ? 34.09629 28.31041  -55.13490 1.000 15.82235 ? 427 LEU B CD1 1 
ATOM   7488 C  CD2 . LEU B  1 428 ? 35.11741 26.02716  -55.25061 1.000 13.74071 ? 427 LEU B CD2 1 
ATOM   7489 N  N   . ILE B  1 429 ? 31.31641 23.53391  -53.26565 1.000 11.83874 ? 428 ILE B N   1 
ATOM   7490 C  CA  . ILE B  1 429 ? 30.27271 23.06094  -52.36223 1.000 15.23574 ? 428 ILE B CA  1 
ATOM   7491 C  C   . ILE B  1 429 ? 29.99732 24.13507  -51.31745 1.000 13.96539 ? 428 ILE B C   1 
ATOM   7492 O  O   . ILE B  1 429 ? 30.89402 24.53595  -50.56652 1.000 14.30857 ? 428 ILE B O   1 
ATOM   7493 C  CB  . ILE B  1 429 ? 30.67599 21.73587  -51.70382 1.000 16.33126 ? 428 ILE B CB  1 
ATOM   7494 C  CG1 . ILE B  1 429 ? 31.03937 20.69989  -52.76848 1.000 8.48836  ? 428 ILE B CG1 1 
ATOM   7495 C  CG2 . ILE B  1 429 ? 29.55121 21.22017  -50.82085 1.000 12.04549 ? 428 ILE B CG2 1 
ATOM   7496 C  CD1 . ILE B  1 429 ? 31.58134 19.40775  -52.19806 1.000 11.21878 ? 428 ILE B CD1 1 
ATOM   7497 N  N   . LEU B  1 430 ? 28.74977 24.60513  -51.26363 1.000 17.91275 ? 429 LEU B N   1 
ATOM   7498 C  CA  . LEU B  1 430 ? 28.38155 25.64459  -50.30688 1.000 15.06191 ? 429 LEU B CA  1 
ATOM   7499 C  C   . LEU B  1 430 ? 28.14767 25.06491  -48.91532 1.000 17.00473 ? 429 LEU B C   1 
ATOM   7500 O  O   . LEU B  1 430 ? 28.87868 25.38098  -47.97045 1.000 23.29770 ? 429 LEU B O   1 
ATOM   7501 C  CB  . LEU B  1 430 ? 27.13897 26.39454  -50.79355 1.000 14.16855 ? 429 LEU B CB  1 
ATOM   7502 C  CG  . LEU B  1 430 ? 27.32755 27.33143  -51.98727 1.000 20.85276 ? 429 LEU B CG  1 
ATOM   7503 C  CD1 . LEU B  1 430 ? 26.02405 28.04433  -52.31296 1.000 23.10510 ? 429 LEU B CD1 1 
ATOM   7504 C  CD2 . LEU B  1 430 ? 28.43589 28.33631  -51.71375 1.000 20.47520 ? 429 LEU B CD2 1 
ATOM   7505 N  N   . ASP B  1 431 ? 27.13250 24.21520  -48.77003 1.000 11.67608 ? 430 ASP B N   1 
ATOM   7506 C  CA  . ASP B  1 431 ? 26.80292 23.64508  -47.47013 1.000 18.52087 ? 430 ASP B CA  1 
ATOM   7507 C  C   . ASP B  1 431 ? 25.87936 22.44894  -47.65928 1.000 20.84154 ? 430 ASP B C   1 
ATOM   7508 O  O   . ASP B  1 431 ? 25.33392 22.22038  -48.74162 1.000 17.21390 ? 430 ASP B O   1 
ATOM   7509 C  CB  . ASP B  1 431 ? 26.15570 24.68834  -46.54924 1.000 17.65617 ? 430 ASP B CB  1 
ATOM   7510 C  CG  . ASP B  1 431 ? 25.09291 25.51866  -47.25538 1.000 25.05715 ? 430 ASP B CG  1 
ATOM   7511 O  OD1 . ASP B  1 431 ? 24.22060 24.93468  -47.93362 1.000 21.47674 ? 430 ASP B OD1 1 
ATOM   7512 O  OD2 . ASP B  1 431 ? 25.12221 26.76055  -47.12121 1.000 25.15002 ? 430 ASP B OD2 1 
ATOM   7513 N  N   . HIS B  1 432 ? 25.71892 21.68365  -46.58024 1.000 18.72268 ? 431 HIS B N   1 
ATOM   7514 C  CA  . HIS B  1 432 ? 24.73728 20.61348  -46.48847 1.000 15.97778 ? 431 HIS B CA  1 
ATOM   7515 C  C   . HIS B  1 432 ? 23.76669 20.93104  -45.35985 1.000 15.29423 ? 431 HIS B C   1 
ATOM   7516 O  O   . HIS B  1 432 ? 24.13457 21.56803  -44.36819 1.000 18.64422 ? 431 HIS B O   1 
ATOM   7517 C  CB  . HIS B  1 432 ? 25.39471 19.24958  -46.22430 1.000 15.98321 ? 431 HIS B CB  1 
ATOM   7518 C  CG  . HIS B  1 432 ? 26.51334 18.91850  -47.16224 1.000 22.95050 ? 431 HIS B CG  1 
ATOM   7519 N  ND1 . HIS B  1 432 ? 26.30221 18.37793  -48.41259 1.000 26.65693 ? 431 HIS B ND1 1 
ATOM   7520 C  CD2 . HIS B  1 432 ? 27.85548 19.03793  -47.02591 1.000 17.30918 ? 431 HIS B CD2 1 
ATOM   7521 C  CE1 . HIS B  1 432 ? 27.46546 18.18591  -49.00912 1.000 21.85283 ? 431 HIS B CE1 1 
ATOM   7522 N  NE2 . HIS B  1 432 ? 28.42386 18.57877  -48.18927 1.000 20.18939 ? 431 HIS B NE2 1 
ATOM   7523 N  N   . ARG B  1 433 ? 22.52553 20.47638  -45.50782 1.000 13.67674 ? 432 ARG B N   1 
ATOM   7524 C  CA  . ARG B  1 433 ? 21.52105 20.76793  -44.49214 1.000 17.98607 ? 432 ARG B CA  1 
ATOM   7525 C  C   . ARG B  1 433 ? 20.38922 19.74690  -44.52706 1.000 15.89968 ? 432 ARG B C   1 
ATOM   7526 O  O   . ARG B  1 433 ? 19.83700 19.46254  -45.59753 1.000 13.94149 ? 432 ARG B O   1 
ATOM   7527 C  CB  . ARG B  1 433 ? 20.96921 22.18200  -44.68370 1.000 18.36744 ? 432 ARG B CB  1 
ATOM   7528 C  CG  . ARG B  1 433 ? 20.09817 22.66478  -43.54062 1.000 15.56845 ? 432 ARG B CG  1 
ATOM   7529 C  CD  . ARG B  1 433 ? 19.65365 24.09612  -43.75574 1.000 15.01100 ? 432 ARG B CD  1 
ATOM   7530 N  NE  . ARG B  1 433 ? 18.79038 24.55631  -42.67569 1.000 17.13948 ? 432 ARG B NE  1 
ATOM   7531 C  CZ  . ARG B  1 433 ? 18.10369 25.68970  -42.69870 1.000 17.53353 ? 432 ARG B CZ  1 
ATOM   7532 N  NH1 . ARG B  1 433 ? 18.14983 26.50437  -43.74082 1.000 14.74491 ? 432 ARG B NH1 1 
ATOM   7533 N  NH2 . ARG B  1 433 ? 17.34762 26.01087  -41.65267 1.000 14.24852 ? 432 ARG B NH2 1 
ATOM   7534 N  N   . PRO B  1 434 ? 20.01261 19.18226  -43.38430 1.000 16.11944 ? 433 PRO B N   1 
ATOM   7535 C  CA  . PRO B  1 434 ? 18.93265 18.19318  -43.36494 1.000 15.76149 ? 433 PRO B CA  1 
ATOM   7536 C  C   . PRO B  1 434 ? 17.56835 18.84331  -43.53728 1.000 15.76111 ? 433 PRO B C   1 
ATOM   7537 O  O   . PRO B  1 434 ? 17.35993 20.01874  -43.23020 1.000 16.30838 ? 433 PRO B O   1 
ATOM   7538 C  CB  . PRO B  1 434 ? 19.06449 17.55871  -41.97688 1.000 15.76219 ? 433 PRO B CB  1 
ATOM   7539 C  CG  . PRO B  1 434 ? 19.63615 18.65157  -41.13789 1.000 13.75715 ? 433 PRO B CG  1 
ATOM   7540 C  CD  . PRO B  1 434 ? 20.57044 19.41831  -42.04044 1.000 12.36109 ? 433 PRO B CD  1 
ATOM   7541 N  N   . PHE B  1 435 ? 16.62763 18.04352  -44.03531 1.000 17.36284 ? 434 PHE B N   1 
ATOM   7542 C  CA  . PHE B  1 435 ? 15.26168 18.49813  -44.24493 1.000 19.71595 ? 434 PHE B CA  1 
ATOM   7543 C  C   . PHE B  1 435 ? 14.29565 17.39193  -43.84341 1.000 15.94151 ? 434 PHE B C   1 
ATOM   7544 O  O   . PHE B  1 435 ? 14.69431 16.26505  -43.53925 1.000 21.47704 ? 434 PHE B O   1 
ATOM   7545 C  CB  . PHE B  1 435 ? 15.02612 18.93247  -45.69979 1.000 20.53238 ? 434 PHE B CB  1 
ATOM   7546 C  CG  . PHE B  1 435 ? 15.04757 17.80074  -46.68946 1.000 16.06586 ? 434 PHE B CG  1 
ATOM   7547 C  CD1 . PHE B  1 435 ? 16.24526 17.33314  -47.20329 1.000 14.74682 ? 434 PHE B CD1 1 
ATOM   7548 C  CD2 . PHE B  1 435 ? 13.86583 17.21762  -47.12033 1.000 16.33827 ? 434 PHE B CD2 1 
ATOM   7549 C  CE1 . PHE B  1 435 ? 16.26567 16.29549  -48.11906 1.000 18.30907 ? 434 PHE B CE1 1 
ATOM   7550 C  CE2 . PHE B  1 435 ? 13.87913 16.18191  -48.03424 1.000 16.88860 ? 434 PHE B CE2 1 
ATOM   7551 C  CZ  . PHE B  1 435 ? 15.08057 15.71999  -48.53426 1.000 19.97625 ? 434 PHE B CZ  1 
ATOM   7552 N  N   . ASP B  1 436 ? 13.00894 17.73188  -43.84158 1.000 19.00871 ? 435 ASP B N   1 
ATOM   7553 C  CA  . ASP B  1 436 ? 11.95521 16.79982  -43.45387 1.000 20.18813 ? 435 ASP B CA  1 
ATOM   7554 C  C   . ASP B  1 436 ? 11.65783 15.87583  -44.62858 1.000 23.13494 ? 435 ASP B C   1 
ATOM   7555 O  O   . ASP B  1 436 ? 11.10872 16.30994  -45.64670 1.000 23.23199 ? 435 ASP B O   1 
ATOM   7556 C  CB  . ASP B  1 436 ? 10.70721 17.56557  -43.02102 1.000 22.13215 ? 435 ASP B CB  1 
ATOM   7557 C  CG  . ASP B  1 436 ? 9.68885  16.68565  -42.31233 1.000 26.36296 ? 435 ASP B CG  1 
ATOM   7558 O  OD1 . ASP B  1 436 ? 9.60504  15.47802  -42.62199 1.000 27.85494 ? 435 ASP B OD1 1 
ATOM   7559 O  OD2 . ASP B  1 436 ? 8.96322  17.20904  -41.44087 1.000 25.03028 ? 435 ASP B OD2 1 
ATOM   7560 N  N   . ILE B  1 437 ? 12.01729 14.59859  -44.48622 1.000 22.78095 ? 436 ILE B N   1 
ATOM   7561 C  CA  . ILE B  1 437 ? 11.73608 13.62407  -45.53568 1.000 24.94286 ? 436 ILE B CA  1 
ATOM   7562 C  C   . ILE B  1 437 ? 10.23727 13.38340  -45.65544 1.000 30.51671 ? 436 ILE B C   1 
ATOM   7563 O  O   . ILE B  1 437 ? 9.68704  13.33700  -46.76277 1.000 22.92381 ? 436 ILE B O   1 
ATOM   7564 C  CB  . ILE B  1 437 ? 12.49295 12.31278  -45.25951 1.000 25.40624 ? 436 ILE B CB  1 
ATOM   7565 C  CG1 . ILE B  1 437 ? 14.00103 12.54950  -45.28530 1.000 24.47559 ? 436 ILE B CG1 1 
ATOM   7566 C  CG2 . ILE B  1 437 ? 12.10780 11.25130  -46.27872 1.000 38.77210 ? 436 ILE B CG2 1 
ATOM   7567 C  CD1 . ILE B  1 437 ? 14.53015 12.85732  -46.65879 1.000 22.34091 ? 436 ILE B CD1 1 
ATOM   7568 N  N   . GLU B  1 438 ? 9.55493  13.22803  -44.51838 1.000 34.72375 ? 437 GLU B N   1 
ATOM   7569 C  CA  . GLU B  1 438 ? 8.13593  12.89004  -44.53703 1.000 34.79827 ? 437 GLU B CA  1 
ATOM   7570 C  C   . GLU B  1 438 ? 7.30824  14.00566  -45.16325 1.000 34.30155 ? 437 GLU B C   1 
ATOM   7571 O  O   . GLU B  1 438 ? 6.41750  13.74454  -45.97977 1.000 38.85901 ? 437 GLU B O   1 
ATOM   7572 C  CB  . GLU B  1 438 ? 7.66275  12.58947  -43.11491 1.000 45.50918 ? 437 GLU B CB  1 
ATOM   7573 C  CG  . GLU B  1 438 ? 6.75559  11.37930  -42.99951 1.000 49.35705 ? 437 GLU B CG  1 
ATOM   7574 C  CD  . GLU B  1 438 ? 5.29309  11.75662  -43.03563 1.000 59.92883 ? 437 GLU B CD  1 
ATOM   7575 O  OE1 . GLU B  1 438 ? 4.98697  12.94509  -42.80371 1.000 53.18726 ? 437 GLU B OE1 1 
ATOM   7576 O  OE2 . GLU B  1 438 ? 4.45050  10.87174  -43.29549 1.000 58.59238 ? 437 GLU B OE2 1 
ATOM   7577 N  N   . ARG B  1 439 ? 7.58918  15.25744  -44.79718 1.000 32.03719 ? 438 ARG B N   1 
ATOM   7578 C  CA  . ARG B  1 439 ? 6.88911  16.38223  -45.40363 1.000 27.56711 ? 438 ARG B CA  1 
ATOM   7579 C  C   . ARG B  1 439 ? 7.23241  16.53755  -46.87836 1.000 27.07584 ? 438 ARG B C   1 
ATOM   7580 O  O   . ARG B  1 439 ? 6.43070  17.09339  -47.63663 1.000 31.54801 ? 438 ARG B O   1 
ATOM   7581 C  CB  . ARG B  1 439 ? 7.22148  17.67134  -44.64923 1.000 24.84887 ? 438 ARG B CB  1 
ATOM   7582 C  CG  . ARG B  1 439 ? 6.26276  18.82001  -44.90788 1.000 31.58544 ? 438 ARG B CG  1 
ATOM   7583 C  CD  . ARG B  1 439 ? 5.22209  18.92299  -43.80425 1.000 51.32085 ? 438 ARG B CD  1 
ATOM   7584 N  NE  . ARG B  1 439 ? 5.80687  19.38319  -42.55005 1.000 48.66351 ? 438 ARG B NE  1 
ATOM   7585 C  CZ  . ARG B  1 439 ? 5.84279  20.65115  -42.16292 1.000 49.24398 ? 438 ARG B CZ  1 
ATOM   7586 N  NH1 . ARG B  1 439 ? 5.32303  21.61521  -42.90549 1.000 39.58164 ? 438 ARG B NH1 1 
ATOM   7587 N  NH2 . ARG B  1 439 ? 6.41349  20.95971  -41.00136 1.000 48.76947 ? 438 ARG B NH2 1 
ATOM   7588 N  N   . TYR B  1 440 ? 8.39564  16.04074  -47.29990 1.000 27.53346 ? 439 TYR B N   1 
ATOM   7589 C  CA  . TYR B  1 440 ? 8.83758  16.20014  -48.67899 1.000 26.02261 ? 439 TYR B CA  1 
ATOM   7590 C  C   . TYR B  1 440 ? 8.10875  15.26067  -49.63094 1.000 27.83027 ? 439 TYR B C   1 
ATOM   7591 O  O   . TYR B  1 440 ? 7.96454  15.57902  -50.81604 1.000 32.23746 ? 439 TYR B O   1 
ATOM   7592 C  CB  . TYR B  1 440 ? 10.34640 15.96960  -48.76046 1.000 23.02909 ? 439 TYR B CB  1 
ATOM   7593 C  CG  . TYR B  1 440 ? 10.98046 16.35540  -50.07649 1.000 19.91835 ? 439 TYR B CG  1 
ATOM   7594 C  CD1 . TYR B  1 440 ? 11.20402 17.68773  -50.39592 1.000 24.58749 ? 439 TYR B CD1 1 
ATOM   7595 C  CD2 . TYR B  1 440 ? 11.37965 15.38716  -50.98790 1.000 20.81044 ? 439 TYR B CD2 1 
ATOM   7596 C  CE1 . TYR B  1 440 ? 11.79228 18.04743  -51.59258 1.000 19.51463 ? 439 TYR B CE1 1 
ATOM   7597 C  CE2 . TYR B  1 440 ? 11.97022 15.73636  -52.18828 1.000 23.95413 ? 439 TYR B CE2 1 
ATOM   7598 C  CZ  . TYR B  1 440 ? 12.17420 17.06811  -52.48335 1.000 23.68205 ? 439 TYR B CZ  1 
ATOM   7599 O  OH  . TYR B  1 440 ? 12.76196 17.42732  -53.67281 1.000 24.84012 ? 439 TYR B OH  1 
ATOM   7600 N  N   . GLN B  1 441 ? 7.64796  14.10899  -49.14251 1.000 28.17121 ? 440 GLN B N   1 
ATOM   7601 C  CA  . GLN B  1 441 ? 6.94599  13.13413  -49.96537 1.000 27.16450 ? 440 GLN B CA  1 
ATOM   7602 C  C   . GLN B  1 441 ? 5.43024  13.28524  -49.88465 1.000 36.53009 ? 440 GLN B C   1 
ATOM   7603 O  O   . GLN B  1 441 ? 4.69983  12.36835  -50.27343 1.000 45.78173 ? 440 GLN B O   1 
ATOM   7604 C  CB  . GLN B  1 441 ? 7.36482  11.71507  -49.57357 1.000 36.55675 ? 440 GLN B CB  1 
ATOM   7605 C  CG  . GLN B  1 441 ? 7.28100  11.41796  -48.08211 1.000 39.77485 ? 440 GLN B CG  1 
ATOM   7606 C  CD  . GLN B  1 441 ? 5.90036  10.96406  -47.64150 1.000 48.79343 ? 440 GLN B CD  1 
ATOM   7607 O  OE1 . GLN B  1 441 ? 5.16173  10.34503  -48.40810 1.000 54.13381 ? 440 GLN B OE1 1 
ATOM   7608 N  NE2 . GLN B  1 441 ? 5.54698  11.26929  -46.39807 1.000 49.67179 ? 440 GLN B NE2 1 
ATOM   7609 N  N   . GLU B  1 442 ? 4.94250  14.42441  -49.39452 1.000 36.63573 ? 441 GLU B N   1 
ATOM   7610 C  CA  . GLU B  1 442 ? 3.50825  14.66651  -49.27846 1.000 34.57513 ? 441 GLU B CA  1 
ATOM   7611 C  C   . GLU B  1 442 ? 3.06395  15.86016  -50.11105 1.000 40.31861 ? 441 GLU B C   1 
ATOM   7612 O  O   . GLU B  1 442 ? 2.16855  15.71944  -50.95063 1.000 46.79397 ? 441 GLU B O   1 
ATOM   7613 C  CB  . GLU B  1 442 ? 3.12951  14.86145  -47.80660 1.000 32.82286 ? 441 GLU B CB  1 
ATOM   7614 C  CG  . GLU B  1 442 ? 3.32888  13.61794  -46.97045 1.000 45.96111 ? 441 GLU B CG  1 
ATOM   7615 C  CD  . GLU B  1 442 ? 3.15670  13.87328  -45.48811 1.000 61.22279 ? 441 GLU B CD  1 
ATOM   7616 O  OE1 . GLU B  1 442 ? 3.15147  15.05510  -45.08013 1.000 58.03567 ? 441 GLU B OE1 1 
ATOM   7617 O  OE2 . GLU B  1 442 ? 3.02798  12.88733  -44.73262 1.000 57.65573 ? 441 GLU B OE2 1 
ATOM   7618 N  N   . ASN B  1 443 ? 3.65582  17.03568  -49.90076 1.000 31.92371 ? 442 ASN B N   1 
ATOM   7619 C  CA  . ASN B  1 443 ? 3.34971  18.21148  -50.70535 1.000 28.74689 ? 442 ASN B CA  1 
ATOM   7620 C  C   . ASN B  1 443 ? 4.57952  18.76693  -51.41014 1.000 25.72152 ? 442 ASN B C   1 
ATOM   7621 O  O   . ASN B  1 443 ? 4.50376  19.84659  -52.00836 1.000 29.81094 ? 442 ASN B O   1 
ATOM   7622 C  CB  . ASN B  1 443 ? 2.69672  19.29994  -49.84493 1.000 37.49447 ? 442 ASN B CB  1 
ATOM   7623 C  CG  . ASN B  1 443 ? 3.51640  19.65310  -48.61278 1.000 36.07077 ? 442 ASN B CG  1 
ATOM   7624 O  OD1 . ASN B  1 443 ? 4.71245  19.36786  -48.53723 1.000 32.14702 ? 442 ASN B OD1 1 
ATOM   7625 N  ND2 . ASN B  1 443 ? 2.86950  20.28439  -47.63921 1.000 30.54874 ? 442 ASN B ND2 1 
ATOM   7626 N  N   . GLY B  1 444 ? 5.70713  18.06110  -51.35786 1.000 23.85135 ? 443 GLY B N   1 
ATOM   7627 C  CA  . GLY B  1 444 ? 6.92008  18.51565  -52.00118 1.000 20.97793 ? 443 GLY B CA  1 
ATOM   7628 C  C   . GLY B  1 444 ? 7.55805  19.74224  -51.39086 1.000 25.30252 ? 443 GLY B C   1 
ATOM   7629 O  O   . GLY B  1 444 ? 8.54861  20.23877  -51.93972 1.000 25.22006 ? 443 GLY B O   1 
ATOM   7630 N  N   . GLU B  1 445 ? 7.02876  20.25386  -50.28287 1.000 25.66807 ? 444 GLU B N   1 
ATOM   7631 C  CA  . GLU B  1 445 ? 7.61565  21.41847  -49.63902 1.000 27.94483 ? 444 GLU B CA  1 
ATOM   7632 C  C   . GLU B  1 445 ? 8.89114  21.02929  -48.90426 1.000 23.41353 ? 444 GLU B C   1 
ATOM   7633 O  O   . GLU B  1 445 ? 8.98539  19.94750  -48.31701 1.000 19.32662 ? 444 GLU B O   1 
ATOM   7634 C  CB  . GLU B  1 445 ? 6.62024  22.06224  -48.67342 1.000 23.05777 ? 444 GLU B CB  1 
ATOM   7635 C  CG  . GLU B  1 445 ? 5.94093  23.30549  -49.23226 1.000 28.17714 ? 444 GLU B CG  1 
ATOM   7636 C  CD  . GLU B  1 445 ? 5.06803  23.00809  -50.43870 1.000 39.02988 ? 444 GLU B CD  1 
ATOM   7637 O  OE1 . GLU B  1 445 ? 4.22678  22.08974  -50.35343 1.000 30.76457 ? 444 GLU B OE1 1 
ATOM   7638 O  OE2 . GLU B  1 445 ? 5.22514  23.68926  -51.47463 1.000 33.76589 ? 444 GLU B OE2 1 
ATOM   7639 N  N   . LEU B  1 446 ? 9.87693  21.92008  -48.94774 1.000 22.41516 ? 445 LEU B N   1 
ATOM   7640 C  CA  . LEU B  1 446 ? 11.19601 21.67293  -48.37373 1.000 17.21876 ? 445 LEU B CA  1 
ATOM   7641 C  C   . LEU B  1 446 ? 11.26727 22.38331  -47.02650 1.000 18.15144 ? 445 LEU B C   1 
ATOM   7642 O  O   . LEU B  1 446 ? 11.41470 23.60659  -46.96229 1.000 20.24011 ? 445 LEU B O   1 
ATOM   7643 C  CB  . LEU B  1 446 ? 12.29054 22.15035  -49.32218 1.000 17.18593 ? 445 LEU B CB  1 
ATOM   7644 C  CG  . LEU B  1 446 ? 13.71601 21.69507  -49.01102 1.000 21.88617 ? 445 LEU B CG  1 
ATOM   7645 C  CD1 . LEU B  1 446 ? 13.83398 20.18748  -49.15732 1.000 20.64715 ? 445 LEU B CD1 1 
ATOM   7646 C  CD2 . LEU B  1 446 ? 14.71502 22.40606  -49.91064 1.000 22.28075 ? 445 LEU B CD2 1 
ATOM   7647 N  N   . VAL B  1 447 ? 11.15702 21.61145  -45.94963 1.000 18.76053 ? 446 VAL B N   1 
ATOM   7648 C  CA  . VAL B  1 447 ? 11.23988 22.12544  -44.58737 1.000 17.41415 ? 446 VAL B CA  1 
ATOM   7649 C  C   . VAL B  1 447 ? 12.52583 21.60003  -43.96812 1.000 14.50170 ? 446 VAL B C   1 
ATOM   7650 O  O   . VAL B  1 447 ? 12.70389 20.38376  -43.82919 1.000 13.77107 ? 446 VAL B O   1 
ATOM   7651 C  CB  . VAL B  1 447 ? 10.01953 21.71578  -43.74970 1.000 22.42981 ? 446 VAL B CB  1 
ATOM   7652 C  CG1 . VAL B  1 447 ? 10.17264 22.20538  -42.31611 1.000 16.23341 ? 446 VAL B CG1 1 
ATOM   7653 C  CG2 . VAL B  1 447 ? 8.74196  22.25346  -44.37521 1.000 20.55336 ? 446 VAL B CG2 1 
ATOM   7654 N  N   . PHE B  1 448 ? 13.42120 22.50988  -43.59886 1.000 14.78493 ? 447 PHE B N   1 
ATOM   7655 C  CA  . PHE B  1 448 ? 14.67880 22.11252  -42.98590 1.000 17.35834 ? 447 PHE B CA  1 
ATOM   7656 C  C   . PHE B  1 448 ? 14.46775 21.74984  -41.52096 1.000 15.95100 ? 447 PHE B C   1 
ATOM   7657 O  O   . PHE B  1 448 ? 13.62080 22.32327  -40.83028 1.000 17.58423 ? 447 PHE B O   1 
ATOM   7658 C  CB  . PHE B  1 448 ? 15.71576 23.22760  -43.11526 1.000 13.37956 ? 447 PHE B CB  1 
ATOM   7659 C  CG  . PHE B  1 448 ? 16.09563 23.53461  -44.53560 1.000 13.29800 ? 447 PHE B CG  1 
ATOM   7660 C  CD1 . PHE B  1 448 ? 16.86971 22.64708  -45.26520 1.000 13.17541 ? 447 PHE B CD1 1 
ATOM   7661 C  CD2 . PHE B  1 448 ? 15.67649 24.70722  -45.14298 1.000 17.30727 ? 447 PHE B CD2 1 
ATOM   7662 C  CE1 . PHE B  1 448 ? 17.22160 22.92381  -46.57281 1.000 16.46152 ? 447 PHE B CE1 1 
ATOM   7663 C  CE2 . PHE B  1 448 ? 16.02364 24.99014  -46.45142 1.000 12.04215 ? 447 PHE B CE2 1 
ATOM   7664 C  CZ  . PHE B  1 448 ? 16.79757 24.09749  -47.16678 1.000 18.11044 ? 447 PHE B CZ  1 
ATOM   7665 N  N   . THR B  1 449 ? 15.24622 20.77330  -41.05137 1.000 16.34983 ? 448 THR B N   1 
ATOM   7666 C  CA  . THR B  1 449 ? 15.09796 20.24060  -39.70162 1.000 15.15800 ? 448 THR B CA  1 
ATOM   7667 C  C   . THR B  1 449 ? 16.39160 20.32461  -38.89874 1.000 17.52597 ? 448 THR B C   1 
ATOM   7668 O  O   . THR B  1 449 ? 16.51311 19.66806  -37.86024 1.000 16.46497 ? 448 THR B O   1 
ATOM   7669 C  CB  . THR B  1 449 ? 14.60867 18.79256  -39.74949 1.000 13.22157 ? 448 THR B CB  1 
ATOM   7670 O  OG1 . THR B  1 449 ? 15.57231 17.98755  -40.44050 1.000 16.47220 ? 448 THR B OG1 1 
ATOM   7671 C  CG2 . THR B  1 449 ? 13.27019 18.70536  -40.46891 1.000 14.32876 ? 448 THR B CG2 1 
ATOM   7672 N  N   . GLY B  1 450 ? 17.36132 21.11367  -39.35440 1.000 16.45521 ? 449 GLY B N   1 
ATOM   7673 C  CA  . GLY B  1 450 ? 18.62865 21.21988  -38.67324 1.000 16.20558 ? 449 GLY B CA  1 
ATOM   7674 C  C   . GLY B  1 450 ? 19.49756 22.33061  -39.22464 1.000 14.86049 ? 449 GLY B C   1 
ATOM   7675 O  O   . GLY B  1 450 ? 19.16423 22.97674  -40.22267 1.000 14.46278 ? 449 GLY B O   1 
ATOM   7676 N  N   . PRO B  1 451 ? 20.63321 22.57624  -38.57745 1.000 14.03228 ? 450 PRO B N   1 
ATOM   7677 C  CA  . PRO B  1 451 ? 21.52102 23.64982  -39.02953 1.000 16.96847 ? 450 PRO B CA  1 
ATOM   7678 C  C   . PRO B  1 451 ? 22.28527 23.25297  -40.28311 1.000 17.54705 ? 450 PRO B C   1 
ATOM   7679 O  O   . PRO B  1 451 ? 22.44761 22.07487  -40.60558 1.000 18.64694 ? 450 PRO B O   1 
ATOM   7680 C  CB  . PRO B  1 451 ? 22.46747 23.84700  -37.84192 1.000 13.96580 ? 450 PRO B CB  1 
ATOM   7681 C  CG  . PRO B  1 451 ? 22.52077 22.50252  -37.19998 1.000 11.74795 ? 450 PRO B CG  1 
ATOM   7682 C  CD  . PRO B  1 451 ? 21.14377 21.90898  -37.36684 1.000 13.95739 ? 450 PRO B CD  1 
ATOM   7683 N  N   . ALA B  1 452 ? 22.75174 24.27073  -40.99976 1.000 20.12258 ? 451 ALA B N   1 
ATOM   7684 C  CA  . ALA B  1 452 ? 23.57177 24.04610  -42.17886 1.000 17.27027 ? 451 ALA B CA  1 
ATOM   7685 C  C   . ALA B  1 452 ? 25.00500 23.73185  -41.77266 1.000 15.37819 ? 451 ALA B C   1 
ATOM   7686 O  O   . ALA B  1 452 ? 25.50406 24.20889  -40.74947 1.000 18.47277 ? 451 ALA B O   1 
ATOM   7687 C  CB  . ALA B  1 452 ? 23.54571 25.26567  -43.10090 1.000 17.18669 ? 451 ALA B CB  1 
ATOM   7688 N  N   . ALA B  1 453 ? 25.66698 22.91424  -42.58789 1.000 18.86997 ? 452 ALA B N   1 
ATOM   7689 C  CA  . ALA B  1 453 ? 27.03494 22.50215  -42.32420 1.000 16.18490 ? 452 ALA B CA  1 
ATOM   7690 C  C   . ALA B  1 453 ? 27.87024 22.71486  -43.58025 1.000 22.60972 ? 452 ALA B C   1 
ATOM   7691 O  O   . ALA B  1 453 ? 27.49430 22.23319  -44.66355 1.000 22.02853 ? 452 ALA B O   1 
ATOM   7692 C  CB  . ALA B  1 453 ? 27.09763 21.03478  -41.88293 1.000 14.53473 ? 452 ALA B CB  1 
ATOM   7693 N  N   . PRO B  1 454 ? 28.99089 23.42318  -43.48788 1.000 23.46180 ? 453 PRO B N   1 
ATOM   7694 C  CA  . PRO B  1 454 ? 29.87516 23.56852  -44.64430 1.000 26.05944 ? 453 PRO B CA  1 
ATOM   7695 C  C   . PRO B  1 454 ? 30.55271 22.24886  -44.96126 1.000 25.28799 ? 453 PRO B C   1 
ATOM   7696 O  O   . PRO B  1 454 ? 30.60735 21.35268  -44.10516 1.000 30.64323 ? 453 PRO B O   1 
ATOM   7697 C  CB  . PRO B  1 454 ? 30.89083 24.62129  -44.17702 1.000 24.75265 ? 453 PRO B CB  1 
ATOM   7698 C  CG  . PRO B  1 454 ? 30.93604 24.44484  -42.69935 1.000 23.77638 ? 453 PRO B CG  1 
ATOM   7699 C  CD  . PRO B  1 454 ? 29.53142 24.08794  -42.28979 1.000 20.06697 ? 453 PRO B CD  1 
ATOM   7700 N  N   . PRO B  1 455 ? 31.07387 22.08144  -46.17405 1.000 24.52111 ? 454 PRO B N   1 
ATOM   7701 C  CA  . PRO B  1 455 ? 31.79863 20.84856  -46.49294 1.000 18.89813 ? 454 PRO B CA  1 
ATOM   7702 C  C   . PRO B  1 455 ? 33.06431 20.72995  -45.65991 1.000 17.51123 ? 454 PRO B C   1 
ATOM   7703 O  O   . PRO B  1 455 ? 33.54963 21.69837  -45.07094 1.000 17.51701 ? 454 PRO B O   1 
ATOM   7704 C  CB  . PRO B  1 455 ? 32.12470 20.99863  -47.98295 1.000 18.57054 ? 454 PRO B CB  1 
ATOM   7705 C  CG  . PRO B  1 455 ? 32.11489 22.46994  -48.22098 1.000 17.21648 ? 454 PRO B CG  1 
ATOM   7706 C  CD  . PRO B  1 455 ? 31.05533 23.01979  -47.31007 1.000 20.49106 ? 454 PRO B CD  1 
ATOM   7707 N  N   . ALA B  1 456 ? 33.59219 19.50927  -45.60687 1.000 22.54021 ? 455 ALA B N   1 
ATOM   7708 C  CA  . ALA B  1 456 ? 34.85180 19.28022  -44.91486 1.000 17.07918 ? 455 ALA B CA  1 
ATOM   7709 C  C   . ALA B  1 456 ? 35.94398 20.15767  -45.51476 1.000 17.61500 ? 455 ALA B C   1 
ATOM   7710 O  O   . ALA B  1 456 ? 35.87268 20.56903  -46.67625 1.000 18.50726 ? 455 ALA B O   1 
ATOM   7711 C  CB  . ALA B  1 456 ? 35.24823 17.80648  -44.99558 1.000 13.93861 ? 455 ALA B CB  1 
ATOM   7712 N  N   . GLN B  1 457 ? 36.96073 20.45350  -44.70145 1.000 20.42036 ? 456 GLN B N   1 
ATOM   7713 C  CA  . GLN B  1 457 ? 38.00224 21.38226  -45.12895 1.000 23.62341 ? 456 GLN B CA  1 
ATOM   7714 C  C   . GLN B  1 457 ? 38.69243 20.91114  -46.40409 1.000 26.11870 ? 456 GLN B C   1 
ATOM   7715 O  O   . GLN B  1 457 ? 39.06494 21.73494  -47.24754 1.000 21.46584 ? 456 GLN B O   1 
ATOM   7716 C  CB  . GLN B  1 457 ? 39.02439 21.57437  -44.00777 1.000 26.20650 ? 456 GLN B CB  1 
ATOM   7717 C  CG  . GLN B  1 457 ? 39.68063 22.94453  -43.99869 1.000 35.60284 ? 456 GLN B CG  1 
ATOM   7718 C  CD  . GLN B  1 457 ? 38.71060 24.04951  -43.62191 1.000 42.46805 ? 456 GLN B CD  1 
ATOM   7719 O  OE1 . GLN B  1 457 ? 37.86141 23.87370  -42.74729 1.000 46.02090 ? 456 GLN B OE1 1 
ATOM   7720 N  NE2 . GLN B  1 457 ? 38.82931 25.19502  -44.28547 1.000 38.57197 ? 456 GLN B NE2 1 
ATOM   7721 N  N   . ASN B  1 458 ? 38.85293 19.59891  -46.57468 1.000 21.04945 ? 457 ASN B N   1 
ATOM   7722 C  CA  . ASN B  1 458 ? 39.51461 19.05551  -47.75426 1.000 19.61453 ? 457 ASN B CA  1 
ATOM   7723 C  C   . ASN B  1 458 ? 38.57968 18.89271  -48.94651 1.000 18.03152 ? 457 ASN B C   1 
ATOM   7724 O  O   . ASN B  1 458 ? 38.99935 18.34218  -49.97025 1.000 14.41626 ? 457 ASN B O   1 
ATOM   7725 C  CB  . ASN B  1 458 ? 40.15639 17.70639  -47.42398 1.000 25.74438 ? 457 ASN B CB  1 
ATOM   7726 C  CG  . ASN B  1 458 ? 39.13959 16.58668  -47.32034 1.000 22.48061 ? 457 ASN B CG  1 
ATOM   7727 O  OD1 . ASN B  1 458 ? 38.01583 16.78936  -46.85684 1.000 26.54690 ? 457 ASN B OD1 1 
ATOM   7728 N  ND2 . ASN B  1 458 ? 39.53013 15.39518  -47.75519 1.000 15.85897 ? 457 ASN B ND2 1 
ATOM   7729 N  N   . GLU B  1 459 ? 37.32804 19.33127  -48.84107 1.000 18.13951 ? 458 GLU B N   1 
ATOM   7730 C  CA  . GLU B  1 459 ? 36.41369 19.34540  -49.97559 1.000 18.02488 ? 458 GLU B CA  1 
ATOM   7731 C  C   . GLU B  1 459 ? 35.99410 20.76961  -50.31885 1.000 15.95444 ? 458 GLU B C   1 
ATOM   7732 O  O   . GLU B  1 459 ? 34.88765 21.00253  -50.80788 1.000 15.51923 ? 458 GLU B O   1 
ATOM   7733 C  CB  . GLU B  1 459 ? 35.19204 18.46877  -49.70581 1.000 14.94249 ? 458 GLU B CB  1 
ATOM   7734 C  CG  . GLU B  1 459 ? 35.51418 16.98358  -49.68023 1.000 14.50765 ? 458 GLU B CG  1 
ATOM   7735 C  CD  . GLU B  1 459 ? 34.29689 16.11031  -49.88472 1.000 13.37287 ? 458 GLU B CD  1 
ATOM   7736 O  OE1 . GLU B  1 459 ? 33.21031 16.65337  -50.17711 1.000 16.12498 ? 458 GLU B OE1 1 
ATOM   7737 O  OE2 . GLU B  1 459 ? 34.42944 14.87542  -49.75409 1.000 17.78225 ? 458 GLU B OE2 1 
ATOM   7738 N  N   . LYS B  1 460 ? 36.87347 21.73361  -50.05825 1.000 16.93379 ? 459 LYS B N   1 
ATOM   7739 C  CA  . LYS B  1 460 ? 36.58365 23.13021  -50.33568 1.000 17.31437 ? 459 LYS B CA  1 
ATOM   7740 C  C   . LYS B  1 460 ? 37.13686 23.60831  -51.67036 1.000 16.30862 ? 459 LYS B C   1 
ATOM   7741 O  O   . LYS B  1 460 ? 36.87086 24.75126  -52.05546 1.000 19.87491 ? 459 LYS B O   1 
ATOM   7742 C  CB  . LYS B  1 460 ? 37.12833 24.02755  -49.21541 1.000 16.97150 ? 459 LYS B CB  1 
ATOM   7743 C  CG  . LYS B  1 460 ? 36.09666 24.40773  -48.15552 1.000 16.65090 ? 459 LYS B CG  1 
ATOM   7744 C  CD  . LYS B  1 460 ? 34.76099 24.84193  -48.77319 1.000 39.18647 ? 459 LYS B CD  1 
ATOM   7745 C  CE  . LYS B  1 460 ? 34.87861 26.08093  -49.66683 1.000 43.70910 ? 459 LYS B CE  1 
ATOM   7746 N  NZ  . LYS B  1 460 ? 33.66416 26.21260  -50.56597 1.000 20.74769 ? 459 LYS B NZ  1 
ATOM   7747 N  N   . GLY B  1 461 ? 37.89317 22.78204  -52.38007 1.000 13.91307 ? 460 GLY B N   1 
ATOM   7748 C  CA  . GLY B  1 461 ? 38.41788 23.16241  -53.67094 1.000 13.61763 ? 460 GLY B CA  1 
ATOM   7749 C  C   . GLY B  1 461 ? 37.40154 22.97197  -54.77965 1.000 14.11134 ? 460 GLY B C   1 
ATOM   7750 O  O   . GLY B  1 461 ? 36.22530 22.68054  -54.55701 1.000 13.90051 ? 460 GLY B O   1 
ATOM   7751 N  N   . LEU B  1 462 ? 37.88251 23.14432  -56.00706 1.000 14.25578 ? 461 LEU B N   1 
ATOM   7752 C  CA  . LEU B  1 462 ? 37.04239 22.94773  -57.17876 1.000 12.86511 ? 461 LEU B CA  1 
ATOM   7753 C  C   . LEU B  1 462 ? 36.67382 21.47537  -57.32003 1.000 10.78731 ? 461 LEU B C   1 
ATOM   7754 O  O   . LEU B  1 462 ? 37.54518 20.60135  -57.30834 1.000 9.73220  ? 461 LEU B O   1 
ATOM   7755 C  CB  . LEU B  1 462 ? 37.76666 23.44409  -58.42817 1.000 16.66695 ? 461 LEU B CB  1 
ATOM   7756 C  CG  . LEU B  1 462 ? 38.13297 24.92993  -58.42565 1.000 15.45681 ? 461 LEU B CG  1 
ATOM   7757 C  CD1 . LEU B  1 462 ? 39.12762 25.24336  -59.53061 1.000 19.96763 ? 461 LEU B CD1 1 
ATOM   7758 C  CD2 . LEU B  1 462 ? 36.88179 25.78319  -58.57279 1.000 12.73583 ? 461 LEU B CD2 1 
ATOM   7759 N  N   . LYS B  1 463 ? 35.37715 21.20295  -57.44785 1.000 13.73128 ? 462 LYS B N   1 
ATOM   7760 C  CA  . LYS B  1 463 ? 34.85926 19.84671  -57.53812 1.000 9.38309  ? 462 LYS B CA  1 
ATOM   7761 C  C   . LYS B  1 463 ? 33.94650 19.72270  -58.74966 1.000 10.70797 ? 462 LYS B C   1 
ATOM   7762 O  O   . LYS B  1 463 ? 33.32094 20.69685  -59.17780 1.000 11.92046 ? 462 LYS B O   1 
ATOM   7763 C  CB  . LYS B  1 463 ? 34.08267 19.46202  -56.26874 1.000 10.03527 ? 462 LYS B CB  1 
ATOM   7764 C  CG  . LYS B  1 463 ? 34.89525 19.53010  -54.98295 1.000 12.52491 ? 462 LYS B CG  1 
ATOM   7765 C  CD  . LYS B  1 463 ? 35.66565 18.24269  -54.75032 1.000 12.57536 ? 462 LYS B CD  1 
ATOM   7766 C  CE  . LYS B  1 463 ? 34.71729 17.08235  -54.49924 1.000 9.79937  ? 462 LYS B CE  1 
ATOM   7767 N  NZ  . LYS B  1 463 ? 35.40997 15.76661  -54.53991 1.000 11.74582 ? 462 LYS B NZ  1 
ATOM   7768 N  N   . ASP B  1 464 ? 33.88169 18.51242  -59.30624 1.000 10.14548 ? 463 ASP B N   1 
ATOM   7769 C  CA  . ASP B  1 464 ? 32.88803 18.18207  -60.31893 1.000 10.85713 ? 463 ASP B CA  1 
ATOM   7770 C  C   . ASP B  1 464 ? 32.01210 17.00358  -59.91413 1.000 12.55212 ? 463 ASP B C   1 
ATOM   7771 O  O   . ASP B  1 464 ? 31.12090 16.61929  -60.68061 1.000 10.92672 ? 463 ASP B O   1 
ATOM   7772 C  CB  . ASP B  1 464 ? 33.55552 17.90085  -61.67705 1.000 9.41314  ? 463 ASP B CB  1 
ATOM   7773 C  CG  . ASP B  1 464 ? 34.54996 16.75296  -61.62659 1.000 10.16819 ? 463 ASP B CG  1 
ATOM   7774 O  OD1 . ASP B  1 464 ? 34.14301 15.61124  -61.32798 1.000 12.08283 ? 463 ASP B OD1 1 
ATOM   7775 O  OD2 . ASP B  1 464 ? 35.74215 16.99020  -61.91051 1.000 14.10516 ? 463 ASP B OD2 1 
ATOM   7776 N  N   . THR B  1 465 ? 32.24214 16.42133  -58.73822 1.000 8.25654  ? 464 THR B N   1 
ATOM   7777 C  CA  . THR B  1 465 ? 31.41211 15.35580  -58.19369 1.000 8.07697  ? 464 THR B CA  1 
ATOM   7778 C  C   . THR B  1 465 ? 31.28816 15.58201  -56.69578 1.000 11.76993 ? 464 THR B C   1 
ATOM   7779 O  O   . THR B  1 465 ? 32.29892 15.78475  -56.01711 1.000 12.76429 ? 464 THR B O   1 
ATOM   7780 C  CB  . THR B  1 465 ? 32.01389 13.97280  -58.47643 1.000 13.62171 ? 464 THR B CB  1 
ATOM   7781 O  OG1 . THR B  1 465 ? 32.23437 13.82202  -59.88505 1.000 17.16989 ? 464 THR B OG1 1 
ATOM   7782 C  CG2 . THR B  1 465 ? 31.07973 12.87119  -57.99172 1.000 7.91366  ? 464 THR B CG2 1 
ATOM   7783 N  N   . VAL B  1 466 ? 30.06026 15.55191  -56.18094 1.000 9.30413  ? 465 VAL B N   1 
ATOM   7784 C  CA  . VAL B  1 466 ? 29.79011 15.88737  -54.78728 1.000 8.68446  ? 465 VAL B CA  1 
ATOM   7785 C  C   . VAL B  1 466 ? 28.94916 14.78367  -54.15689 1.000 13.36963 ? 465 VAL B C   1 
ATOM   7786 O  O   . VAL B  1 466 ? 27.97352 14.31666  -54.75546 1.000 12.77664 ? 465 VAL B O   1 
ATOM   7787 C  CB  . VAL B  1 466 ? 29.08528 17.25333  -54.65925 1.000 10.44940 ? 465 VAL B CB  1 
ATOM   7788 C  CG1 . VAL B  1 466 ? 27.89798 17.34065  -55.61253 1.000 7.12855  ? 465 VAL B CG1 1 
ATOM   7789 C  CG2 . VAL B  1 466 ? 28.64462 17.49803  -53.22131 1.000 9.01706  ? 465 VAL B CG2 1 
ATOM   7790 N  N   . LYS B  1 467 ? 29.33246 14.36532  -52.95240 1.000 13.01185 ? 466 LYS B N   1 
ATOM   7791 C  CA  . LYS B  1 467 ? 28.55881 13.39959  -52.17908 1.000 11.26373 ? 466 LYS B CA  1 
ATOM   7792 C  C   . LYS B  1 467 ? 27.37591 14.11644  -51.54245 1.000 14.66965 ? 466 LYS B C   1 
ATOM   7793 O  O   . LYS B  1 467 ? 27.55581 14.94625  -50.64533 1.000 19.69996 ? 466 LYS B O   1 
ATOM   7794 C  CB  . LYS B  1 467 ? 29.43742 12.74775  -51.11482 1.000 9.76241  ? 466 LYS B CB  1 
ATOM   7795 C  CG  . LYS B  1 467 ? 30.55968 11.89225  -51.67022 1.000 12.35885 ? 466 LYS B CG  1 
ATOM   7796 C  CD  . LYS B  1 467 ? 31.38863 11.26225  -50.56314 1.000 9.98909  ? 466 LYS B CD  1 
ATOM   7797 C  CE  . LYS B  1 467 ? 32.19164 12.30756  -49.80555 1.000 12.18004 ? 466 LYS B CE  1 
ATOM   7798 N  NZ  . LYS B  1 467 ? 33.28227 12.89492  -50.63338 1.000 8.03532  ? 466 LYS B NZ  1 
ATOM   7799 N  N   . VAL B  1 468 ? 26.16563 13.81388  -52.00204 1.000 15.72649 ? 467 VAL B N   1 
ATOM   7800 C  CA  . VAL B  1 468 ? 24.94981 14.41465  -51.46107 1.000 12.82994 ? 467 VAL B CA  1 
ATOM   7801 C  C   . VAL B  1 468 ? 24.43151 13.48491  -50.36567 1.000 13.18186 ? 467 VAL B C   1 
ATOM   7802 O  O   . VAL B  1 468 ? 23.98027 12.37033  -50.68310 1.000 10.18037 ? 467 VAL B O   1 
ATOM   7803 C  CB  . VAL B  1 468 ? 23.89252 14.62867  -52.55108 1.000 11.79669 ? 467 VAL B CB  1 
ATOM   7804 C  CG1 . VAL B  1 468 ? 22.67939 15.31536  -51.97136 1.000 14.43719 ? 467 VAL B CG1 1 
ATOM   7805 C  CG2 . VAL B  1 468 ? 24.46484 15.43138  -53.69471 1.000 12.15633 ? 467 VAL B CG2 1 
ATOM   7806 N  N   . PRO B  1 469 ? 24.50252 13.87557  -49.08875 1.000 13.08571 ? 468 PRO B N   1 
ATOM   7807 C  CA  . PRO B  1 469 ? 24.14187 12.94336  -48.02048 1.000 13.43172 ? 468 PRO B CA  1 
ATOM   7808 C  C   . PRO B  1 469 ? 22.65949 12.64059  -48.03691 1.000 11.43040 ? 468 PRO B C   1 
ATOM   7809 O  O   . PRO B  1 469 ? 21.85088 13.43425  -48.55016 1.000 12.73219 ? 468 PRO B O   1 
ATOM   7810 C  CB  . PRO B  1 469 ? 24.55274 13.69603  -46.73915 1.000 14.71543 ? 468 PRO B CB  1 
ATOM   7811 C  CG  . PRO B  1 469 ? 25.49744 14.74310  -47.18301 1.000 14.79646 ? 468 PRO B CG  1 
ATOM   7812 C  CD  . PRO B  1 469 ? 25.04510 15.13689  -48.55982 1.000 14.13850 ? 468 PRO B CD  1 
ATOM   7813 N  N   . PRO B  1 470 ? 22.24896 11.48851  -47.51205 1.000 14.36231 ? 469 PRO B N   1 
ATOM   7814 C  CA  . PRO B  1 470 ? 20.82407 11.15757  -47.48176 1.000 14.43914 ? 469 PRO B CA  1 
ATOM   7815 C  C   . PRO B  1 470 ? 20.07033 12.06340  -46.52289 1.000 10.69718 ? 469 PRO B C   1 
ATOM   7816 O  O   . PRO B  1 470 ? 20.58938 12.47914  -45.48408 1.000 14.91923 ? 469 PRO B O   1 
ATOM   7817 C  CB  . PRO B  1 470 ? 20.80531 9.70313   -47.00365 1.000 17.60248 ? 469 PRO B CB  1 
ATOM   7818 C  CG  . PRO B  1 470 ? 22.05307 9.56861   -46.20307 1.000 11.04494 ? 469 PRO B CG  1 
ATOM   7819 C  CD  . PRO B  1 470 ? 23.07277 10.43229  -46.89497 1.000 15.78815 ? 469 PRO B CD  1 
ATOM   7820 N  N   . GLY B  1 471 ? 18.82949 12.36967  -46.88973 1.000 12.41382 ? 470 GLY B N   1 
ATOM   7821 C  CA  . GLY B  1 471 ? 18.00431 13.23448  -46.07091 1.000 12.14701 ? 470 GLY B CA  1 
ATOM   7822 C  C   . GLY B  1 471 ? 18.52516 14.64332  -45.91921 1.000 13.28808 ? 470 GLY B C   1 
ATOM   7823 O  O   . GLY B  1 471 ? 18.16662 15.32641  -44.95724 1.000 14.06723 ? 470 GLY B O   1 
ATOM   7824 N  N   . SER B  1 472 ? 19.36451 15.10198  -46.84518 1.000 11.33240 ? 471 SER B N   1 
ATOM   7825 C  CA  . SER B  1 472 ? 19.97153 16.41964  -46.75475 1.000 12.72265 ? 471 SER B CA  1 
ATOM   7826 C  C   . SER B  1 472 ? 19.91425 17.09972  -48.11347 1.000 14.21249 ? 471 SER B C   1 
ATOM   7827 O  O   . SER B  1 472 ? 19.76636 16.45188  -49.15233 1.000 12.63581 ? 471 SER B O   1 
ATOM   7828 C  CB  . SER B  1 472 ? 21.42578 16.34160  -46.27080 1.000 10.72846 ? 471 SER B CB  1 
ATOM   7829 O  OG  . SER B  1 472 ? 21.51160 15.68618  -45.01840 1.000 19.18508 ? 471 SER B OG  1 
ATOM   7830 N  N   . VAL B  1 473 ? 20.03646 18.42333  -48.09022 1.000 13.00245 ? 472 VAL B N   1 
ATOM   7831 C  CA  . VAL B  1 473 ? 20.09926 19.23968  -49.29562 1.000 10.63238 ? 472 VAL B CA  1 
ATOM   7832 C  C   . VAL B  1 473 ? 21.52463 19.75125  -49.43463 1.000 12.88025 ? 472 VAL B C   1 
ATOM   7833 O  O   . VAL B  1 473 ? 22.02335 20.46568  -48.55639 1.000 21.93482 ? 472 VAL B O   1 
ATOM   7834 C  CB  . VAL B  1 473 ? 19.09858 20.40408  -49.24993 1.000 15.65752 ? 472 VAL B CB  1 
ATOM   7835 C  CG1 . VAL B  1 473 ? 19.31972 21.33672  -50.43068 1.000 13.43939 ? 472 VAL B CG1 1 
ATOM   7836 C  CG2 . VAL B  1 473 ? 17.67203 19.87812  -49.24453 1.000 17.66906 ? 472 VAL B CG2 1 
ATOM   7837 N  N   . THR B  1 474 ? 22.18086 19.38390  -50.53057 1.000 14.06196 ? 473 THR B N   1 
ATOM   7838 C  CA  . THR B  1 474 ? 23.52897 19.84582  -50.83182 1.000 12.70607 ? 473 THR B CA  1 
ATOM   7839 C  C   . THR B  1 474 ? 23.44985 20.99413  -51.82947 1.000 16.91406 ? 473 THR B C   1 
ATOM   7840 O  O   . THR B  1 474 ? 22.98022 20.81097  -52.95854 1.000 19.33019 ? 473 THR B O   1 
ATOM   7841 C  CB  . THR B  1 474 ? 24.38921 18.71353  -51.39057 1.000 15.74137 ? 473 THR B CB  1 
ATOM   7842 O  OG1 . THR B  1 474 ? 24.67194 17.76901  -50.35182 1.000 15.08609 ? 473 THR B OG1 1 
ATOM   7843 C  CG2 . THR B  1 474 ? 25.69659 19.26294  -51.94168 1.000 16.19968 ? 473 THR B CG2 1 
ATOM   7844 N  N   . ARG B  1 475 ? 23.90536 22.17088  -51.40943 1.000 14.58101 ? 474 ARG B N   1 
ATOM   7845 C  CA  . ARG B  1 475 ? 23.94033 23.34672  -52.26741 1.000 14.23766 ? 474 ARG B CA  1 
ATOM   7846 C  C   . ARG B  1 475 ? 25.29370 23.43992  -52.96003 1.000 12.88591 ? 474 ARG B C   1 
ATOM   7847 O  O   . ARG B  1 475 ? 26.33869 23.36470  -52.30697 1.000 10.98692 ? 474 ARG B O   1 
ATOM   7848 C  CB  . ARG B  1 475 ? 23.67372 24.61400  -51.45351 1.000 13.69025 ? 474 ARG B CB  1 
ATOM   7849 C  CG  . ARG B  1 475 ? 22.23621 25.10106  -51.50438 1.000 17.13634 ? 474 ARG B CG  1 
ATOM   7850 C  CD  . ARG B  1 475 ? 21.80519 25.71635  -50.18081 1.000 17.52851 ? 474 ARG B CD  1 
ATOM   7851 N  NE  . ARG B  1 475 ? 22.79982 26.63079  -49.63182 1.000 22.39835 ? 474 ARG B NE  1 
ATOM   7852 C  CZ  . ARG B  1 475 ? 22.86150 27.92692  -49.90594 1.000 27.24864 ? 474 ARG B CZ  1 
ATOM   7853 N  NH1 . ARG B  1 475 ? 22.01577 28.49665  -50.74909 1.000 23.31516 ? 474 ARG B NH1 1 
ATOM   7854 N  NH2 . ARG B  1 475 ? 23.79490 28.67050  -49.31853 1.000 29.72416 ? 474 ARG B NH2 1 
ATOM   7855 N  N   . ILE B  1 476 ? 25.27180 23.59207  -54.28214 1.000 15.87592 ? 475 ILE B N   1 
ATOM   7856 C  CA  . ILE B  1 476 ? 26.48180 23.80800  -55.06365 1.000 12.64707 ? 475 ILE B CA  1 
ATOM   7857 C  C   . ILE B  1 476 ? 26.29271 25.06492  -55.89880 1.000 12.91855 ? 475 ILE B C   1 
ATOM   7858 O  O   . ILE B  1 476 ? 25.17295 25.41498  -56.28506 1.000 17.92087 ? 475 ILE B O   1 
ATOM   7859 C  CB  . ILE B  1 476 ? 26.82994 22.60128  -55.96730 1.000 10.99497 ? 475 ILE B CB  1 
ATOM   7860 C  CG1 . ILE B  1 476 ? 25.79897 22.44603  -57.08663 1.000 11.14234 ? 475 ILE B CG1 1 
ATOM   7861 C  CG2 . ILE B  1 476 ? 26.92284 21.32333  -55.14707 1.000 8.05852  ? 475 ILE B CG2 1 
ATOM   7862 C  CD1 . ILE B  1 476 ? 26.14126 21.36579  -58.08871 1.000 9.45688  ? 475 ILE B CD1 1 
ATOM   7863 N  N   . ILE B  1 477 ? 27.39827 25.75278  -56.16949 1.000 11.45924 ? 476 ILE B N   1 
ATOM   7864 C  CA  . ILE B  1 477 ? 27.39476 26.96839  -56.97438 1.000 12.76054 ? 476 ILE B CA  1 
ATOM   7865 C  C   . ILE B  1 477 ? 28.35444 26.77401  -58.14085 1.000 13.56656 ? 476 ILE B C   1 
ATOM   7866 O  O   . ILE B  1 477 ? 29.50269 26.35836  -57.94672 1.000 11.89982 ? 476 ILE B O   1 
ATOM   7867 C  CB  . ILE B  1 477 ? 27.76477 28.21060  -56.13914 1.000 16.32364 ? 476 ILE B CB  1 
ATOM   7868 C  CG1 . ILE B  1 477 ? 27.79989 29.46027  -57.02153 1.000 11.74447 ? 476 ILE B CG1 1 
ATOM   7869 C  CG2 . ILE B  1 477 ? 29.08821 28.01326  -55.40205 1.000 13.17356 ? 476 ILE B CG2 1 
ATOM   7870 C  CD1 . ILE B  1 477 ? 27.80906 30.75393  -56.24053 1.000 20.75319 ? 476 ILE B CD1 1 
ATOM   7871 N  N   . ALA B  1 478 ? 27.87997 27.06054  -59.35167 1.000 15.81701 ? 477 ALA B N   1 
ATOM   7872 C  CA  . ALA B  1 478 ? 28.65397 26.80006  -60.55507 1.000 17.28618 ? 477 ALA B CA  1 
ATOM   7873 C  C   . ALA B  1 478 ? 28.45445 27.92366  -61.56041 1.000 16.57589 ? 477 ALA B C   1 
ATOM   7874 O  O   . ALA B  1 478 ? 27.38478 28.53482  -61.63281 1.000 14.98370 ? 477 ALA B O   1 
ATOM   7875 C  CB  . ALA B  1 478 ? 28.26742 25.45753  -61.19274 1.000 10.72437 ? 477 ALA B CB  1 
ATOM   7876 N  N   . THR B  1 479 ? 29.50328 28.18497  -62.33654 1.000 14.04687 ? 478 THR B N   1 
ATOM   7877 C  CA  . THR B  1 479 ? 29.47105 29.13656  -63.43977 1.000 12.09770 ? 478 THR B CA  1 
ATOM   7878 C  C   . THR B  1 479 ? 29.63476 28.36077  -64.73957 1.000 15.20688 ? 478 THR B C   1 
ATOM   7879 O  O   . THR B  1 479 ? 30.66917 27.72101  -64.95747 1.000 18.75549 ? 478 THR B O   1 
ATOM   7880 C  CB  . THR B  1 479 ? 30.57376 30.18516  -63.29863 1.000 14.55016 ? 478 THR B CB  1 
ATOM   7881 O  OG1 . THR B  1 479 ? 30.49485 30.79287  -62.00408 1.000 20.45387 ? 478 THR B OG1 1 
ATOM   7882 C  CG2 . THR B  1 479 ? 30.42656 31.25791  -64.36767 1.000 13.17174 ? 478 THR B CG2 1 
ATOM   7883 N  N   . PHE B  1 480 ? 28.62044 28.41828  -65.59778 1.000 16.27449 ? 479 PHE B N   1 
ATOM   7884 C  CA  . PHE B  1 480 ? 28.58538 27.60802  -66.81401 1.000 14.76023 ? 479 PHE B CA  1 
ATOM   7885 C  C   . PHE B  1 480 ? 29.30423 28.35944  -67.92689 1.000 13.76162 ? 479 PHE B C   1 
ATOM   7886 O  O   . PHE B  1 480 ? 28.71820 29.20391  -68.60875 1.000 17.33319 ? 479 PHE B O   1 
ATOM   7887 C  CB  . PHE B  1 480 ? 27.14665 27.26420  -67.17798 1.000 12.94765 ? 479 PHE B CB  1 
ATOM   7888 C  CG  . PHE B  1 480 ? 26.48586 26.36080  -66.18115 1.000 11.44823 ? 479 PHE B CG  1 
ATOM   7889 C  CD1 . PHE B  1 480 ? 25.86304 26.88234  -65.06075 1.000 10.90292 ? 479 PHE B CD1 1 
ATOM   7890 C  CD2 . PHE B  1 480 ? 26.51762 24.98632  -66.34629 1.000 15.47659 ? 479 PHE B CD2 1 
ATOM   7891 C  CE1 . PHE B  1 480 ? 25.26695 26.05154  -64.13332 1.000 14.41352 ? 479 PHE B CE1 1 
ATOM   7892 C  CE2 . PHE B  1 480 ? 25.92288 24.14906  -65.42187 1.000 11.93439 ? 479 PHE B CE2 1 
ATOM   7893 C  CZ  . PHE B  1 480 ? 25.29704 24.68239  -64.31424 1.000 11.59416 ? 479 PHE B CZ  1 
ATOM   7894 N  N   . ALA B  1 481 ? 30.58094 28.03862  -68.11004 1.000 15.29328 ? 480 ALA B N   1 
ATOM   7895 C  CA  . ALA B  1 481 ? 31.44353 28.70711  -69.07221 1.000 20.90122 ? 480 ALA B CA  1 
ATOM   7896 C  C   . ALA B  1 481 ? 32.56734 27.74937  -69.44298 1.000 19.03751 ? 480 ALA B C   1 
ATOM   7897 O  O   . ALA B  1 481 ? 32.85100 26.80629  -68.69428 1.000 13.64901 ? 480 ALA B O   1 
ATOM   7898 C  CB  . ALA B  1 481 ? 32.00751 30.01655  -68.49312 1.000 14.40736 ? 480 ALA B CB  1 
ATOM   7899 N  N   . PRO B  1 482 ? 33.22994 27.95952  -70.59349 1.000 22.08446 ? 481 PRO B N   1 
ATOM   7900 C  CA  . PRO B  1 482 ? 33.02873 29.00066  -71.60400 1.000 20.27106 ? 481 PRO B CA  1 
ATOM   7901 C  C   . PRO B  1 482 ? 32.39857 28.46599  -72.88387 1.000 21.72463 ? 481 PRO B C   1 
ATOM   7902 O  O   . PRO B  1 482 ? 32.32554 29.16983  -73.88857 1.000 18.15768 ? 481 PRO B O   1 
ATOM   7903 C  CB  . PRO B  1 482 ? 34.45979 29.49539  -71.84211 1.000 13.22918 ? 481 PRO B CB  1 
ATOM   7904 C  CG  . PRO B  1 482 ? 35.34186 28.25606  -71.58265 1.000 17.33670 ? 481 PRO B CG  1 
ATOM   7905 C  CD  . PRO B  1 482 ? 34.47462 27.22643  -70.86986 1.000 17.49334 ? 481 PRO B CD  1 
ATOM   7906 N  N   . TYR B  1 483 ? 31.93861 27.21965  -72.87711 1.000 15.75070 ? 482 TYR B N   1 
ATOM   7907 C  CA  . TYR B  1 483 ? 31.38447 26.57665  -74.05881 1.000 18.68678 ? 482 TYR B CA  1 
ATOM   7908 C  C   . TYR B  1 483 ? 29.88523 26.39544  -73.88084 1.000 16.02834 ? 482 TYR B C   1 
ATOM   7909 O  O   . TYR B  1 483 ? 29.43569 25.87541  -72.85442 1.000 19.11098 ? 482 TYR B O   1 
ATOM   7910 C  CB  . TYR B  1 483 ? 32.04995 25.22094  -74.30788 1.000 21.74763 ? 482 TYR B CB  1 
ATOM   7911 C  CG  . TYR B  1 483 ? 33.55964 25.27152  -74.35736 1.000 19.72717 ? 482 TYR B CG  1 
ATOM   7912 C  CD1 . TYR B  1 483 ? 34.21937 26.18582  -75.16932 1.000 16.32807 ? 482 TYR B CD1 1 
ATOM   7913 C  CD2 . TYR B  1 483 ? 34.32605 24.40943  -73.58318 1.000 17.97787 ? 482 TYR B CD2 1 
ATOM   7914 C  CE1 . TYR B  1 483 ? 35.60237 26.23548  -75.21351 1.000 13.59381 ? 482 TYR B CE1 1 
ATOM   7915 C  CE2 . TYR B  1 483 ? 35.70817 24.45275  -73.61956 1.000 21.96750 ? 482 TYR B CE2 1 
ATOM   7916 C  CZ  . TYR B  1 483 ? 36.34023 25.36673  -74.43620 1.000 17.49956 ? 482 TYR B CZ  1 
ATOM   7917 O  OH  . TYR B  1 483 ? 37.71416 25.41009  -74.47325 1.000 19.13089 ? 482 TYR B OH  1 
ATOM   7918 N  N   . SER B  1 484 ? 29.11941 26.82959  -74.87247 1.000 17.76606 ? 483 SER B N   1 
ATOM   7919 C  CA  . SER B  1 484 ? 27.69302 26.55849  -74.90515 1.000 20.57530 ? 483 SER B CA  1 
ATOM   7920 C  C   . SER B  1 484 ? 27.43154 25.26977  -75.67615 1.000 19.40184 ? 483 SER B C   1 
ATOM   7921 O  O   . SER B  1 484 ? 28.25221 24.81932  -76.47923 1.000 21.62852 ? 483 SER B O   1 
ATOM   7922 C  CB  . SER B  1 484 ? 26.93180 27.72245  -75.54063 1.000 17.03251 ? 483 SER B CB  1 
ATOM   7923 O  OG  . SER B  1 484 ? 27.34285 27.92923  -76.87955 1.000 23.28393 ? 483 SER B OG  1 
ATOM   7924 N  N   . GLY B  1 485 ? 26.27544 24.66906  -75.41336 1.000 17.35322 ? 484 GLY B N   1 
ATOM   7925 C  CA  . GLY B  1 485 ? 25.91490 23.44643  -76.10058 1.000 14.66851 ? 484 GLY B CA  1 
ATOM   7926 C  C   . GLY B  1 485 ? 25.25220 22.41064  -75.21834 1.000 17.16627 ? 484 GLY B C   1 
ATOM   7927 O  O   . GLY B  1 485 ? 24.63043 22.74620  -74.20565 1.000 16.41824 ? 484 GLY B O   1 
ATOM   7928 N  N   . ARG B  1 486 ? 25.38933 21.14240  -75.59216 1.000 14.32937 ? 485 ARG B N   1 
ATOM   7929 C  CA  . ARG B  1 486 ? 24.69437 20.04169  -74.93886 1.000 18.47973 ? 485 ARG B CA  1 
ATOM   7930 C  C   . ARG B  1 486 ? 25.68116 19.23716  -74.10260 1.000 20.99416 ? 485 ARG B C   1 
ATOM   7931 O  O   . ARG B  1 486 ? 26.62332 18.64565  -74.64162 1.000 23.07081 ? 485 ARG B O   1 
ATOM   7932 C  CB  . ARG B  1 486 ? 24.00790 19.14963  -75.97380 1.000 22.15589 ? 485 ARG B CB  1 
ATOM   7933 C  CG  . ARG B  1 486 ? 23.36442 17.89928  -75.40161 1.000 20.67716 ? 485 ARG B CG  1 
ATOM   7934 C  CD  . ARG B  1 486 ? 22.25755 18.22469  -74.40787 1.000 22.37308 ? 485 ARG B CD  1 
ATOM   7935 N  NE  . ARG B  1 486 ? 21.11491 18.87397  -75.04002 1.000 26.29498 ? 485 ARG B NE  1 
ATOM   7936 C  CZ  . ARG B  1 486 ? 20.10863 18.22894  -75.61569 1.000 33.10548 ? 485 ARG B CZ  1 
ATOM   7937 N  NH1 . ARG B  1 486 ? 20.07855 16.90707  -75.67812 1.000 26.07289 ? 485 ARG B NH1 1 
ATOM   7938 N  NH2 . ARG B  1 486 ? 19.10731 18.92761  -76.14289 1.000 31.77960 ? 485 ARG B NH2 1 
ATOM   7939 N  N   . TYR B  1 487 ? 25.46499 19.22558  -72.79315 1.000 17.04743 ? 486 TYR B N   1 
ATOM   7940 C  CA  . TYR B  1 487 ? 26.18572 18.37712  -71.85521 1.000 15.96828 ? 486 TYR B CA  1 
ATOM   7941 C  C   . TYR B  1 487 ? 25.16944 17.53676  -71.08270 1.000 15.36222 ? 486 TYR B C   1 
ATOM   7942 O  O   . TYR B  1 487 ? 23.97877 17.50986  -71.40818 1.000 14.41647 ? 486 TYR B O   1 
ATOM   7943 C  CB  . TYR B  1 487 ? 27.05279 19.21674  -70.91431 1.000 14.68189 ? 486 TYR B CB  1 
ATOM   7944 C  CG  . TYR B  1 487 ? 28.13449 20.01321  -71.60544 1.000 17.35335 ? 486 TYR B CG  1 
ATOM   7945 C  CD1 . TYR B  1 487 ? 27.88252 21.29109  -72.08884 1.000 16.93892 ? 486 TYR B CD1 1 
ATOM   7946 C  CD2 . TYR B  1 487 ? 29.41151 19.49170  -71.76564 1.000 18.87635 ? 486 TYR B CD2 1 
ATOM   7947 C  CE1 . TYR B  1 487 ? 28.87007 22.02487  -72.71832 1.000 16.29860 ? 486 TYR B CE1 1 
ATOM   7948 C  CE2 . TYR B  1 487 ? 30.40622 20.21805  -72.39428 1.000 19.43236 ? 486 TYR B CE2 1 
ATOM   7949 C  CZ  . TYR B  1 487 ? 30.12983 21.48327  -72.86826 1.000 19.60799 ? 486 TYR B CZ  1 
ATOM   7950 O  OH  . TYR B  1 487 ? 31.11697 22.20807  -73.49354 1.000 19.25784 ? 486 TYR B OH  1 
ATOM   7951 N  N   . VAL B  1 488 ? 25.64672 16.84321  -70.04792 1.000 15.30721 ? 487 VAL B N   1 
ATOM   7952 C  CA  . VAL B  1 488 ? 24.78397 16.06393  -69.16975 1.000 17.36291 ? 487 VAL B CA  1 
ATOM   7953 C  C   . VAL B  1 488 ? 25.24444 16.24722  -67.73119 1.000 14.84106 ? 487 VAL B C   1 
ATOM   7954 O  O   . VAL B  1 488 ? 26.35031 16.71739  -67.45828 1.000 17.40970 ? 487 VAL B O   1 
ATOM   7955 C  CB  . VAL B  1 488 ? 24.76305 14.55541  -69.51956 1.000 12.73711 ? 487 VAL B CB  1 
ATOM   7956 C  CG1 . VAL B  1 488 ? 24.24114 14.32299  -70.92969 1.000 14.26968 ? 487 VAL B CG1 1 
ATOM   7957 C  CG2 . VAL B  1 488 ? 26.13919 13.95281  -69.35011 1.000 10.41723 ? 487 VAL B CG2 1 
ATOM   7958 N  N   . TRP B  1 489 ? 24.36443 15.87400  -66.80790 1.000 17.26000 ? 488 TRP B N   1 
ATOM   7959 C  CA  . TRP B  1 489 ? 24.69048 15.77377  -65.39487 1.000 16.92234 ? 488 TRP B CA  1 
ATOM   7960 C  C   . TRP B  1 489 ? 23.95415 14.56537  -64.84075 1.000 17.09259 ? 488 TRP B C   1 
ATOM   7961 O  O   . TRP B  1 489 ? 22.84346 14.24977  -65.27623 1.000 19.76280 ? 488 TRP B O   1 
ATOM   7962 C  CB  . TRP B  1 489 ? 24.31021 17.04471  -64.62214 1.000 11.76027 ? 488 TRP B CB  1 
ATOM   7963 C  CG  . TRP B  1 489 ? 22.83785 17.21002  -64.43630 1.000 12.61951 ? 488 TRP B CG  1 
ATOM   7964 C  CD1 . TRP B  1 489 ? 21.92760 17.57555  -65.38439 1.000 16.14872 ? 488 TRP B CD1 1 
ATOM   7965 C  CD2 . TRP B  1 489 ? 22.10032 17.01840  -63.22424 1.000 12.91684 ? 488 TRP B CD2 1 
ATOM   7966 N  NE1 . TRP B  1 489 ? 20.66793 17.62081  -64.83876 1.000 16.68898 ? 488 TRP B NE1 1 
ATOM   7967 C  CE2 . TRP B  1 489 ? 20.74704 17.28311  -63.51325 1.000 13.70027 ? 488 TRP B CE2 1 
ATOM   7968 C  CE3 . TRP B  1 489 ? 22.45252 16.64675  -61.92309 1.000 13.60157 ? 488 TRP B CE3 1 
ATOM   7969 C  CZ2 . TRP B  1 489 ? 19.74620 17.18661  -62.55099 1.000 12.52853 ? 488 TRP B CZ2 1 
ATOM   7970 C  CZ3 . TRP B  1 489 ? 21.45695 16.55340  -60.96759 1.000 16.99205 ? 488 TRP B CZ3 1 
ATOM   7971 C  CH2 . TRP B  1 489 ? 20.11984 16.82392  -61.28627 1.000 15.91916 ? 488 TRP B CH2 1 
ATOM   7972 N  N   . HIS B  1 490 ? 24.57894 13.88358  -63.88642 1.000 16.17141 ? 489 HIS B N   1 
ATOM   7973 C  CA  . HIS B  1 490 ? 24.05318 12.59927  -63.44381 1.000 15.48155 ? 489 HIS B CA  1 
ATOM   7974 C  C   . HIS B  1 490 ? 24.74837 12.18408  -62.15701 1.000 14.57416 ? 489 HIS B C   1 
ATOM   7975 O  O   . HIS B  1 490 ? 25.77429 12.74793  -61.76734 1.000 14.59594 ? 489 HIS B O   1 
ATOM   7976 C  CB  . HIS B  1 490 ? 24.24730 11.52961  -64.51992 1.000 14.22458 ? 489 HIS B CB  1 
ATOM   7977 C  CG  . HIS B  1 490 ? 25.66872 11.37248  -64.95930 1.000 17.17610 ? 489 HIS B CG  1 
ATOM   7978 N  ND1 . HIS B  1 490 ? 26.56492 10.55471  -64.30528 1.000 13.98805 ? 489 HIS B ND1 1 
ATOM   7979 C  CD2 . HIS B  1 490 ? 26.35321 11.94078  -65.97991 1.000 18.75849 ? 489 HIS B CD2 1 
ATOM   7980 C  CE1 . HIS B  1 490 ? 27.73779 10.61909  -64.90983 1.000 14.15529 ? 489 HIS B CE1 1 
ATOM   7981 N  NE2 . HIS B  1 490 ? 27.63621 11.45360  -65.92860 1.000 14.36477 ? 489 HIS B NE2 1 
ATOM   7982 N  N   . CYS B  1 491 ? 24.16673 11.18323  -61.50267 1.000 12.57170 ? 490 CYS B N   1 
ATOM   7983 C  CA  . CYS B  1 491 ? 24.84069 10.48267  -60.42192 1.000 16.60008 ? 490 CYS B CA  1 
ATOM   7984 C  C   . CYS B  1 491 ? 25.87613 9.53065   -61.00393 1.000 15.42373 ? 490 CYS B C   1 
ATOM   7985 O  O   . CYS B  1 491 ? 25.61813 8.84320   -61.99625 1.000 16.98146 ? 490 CYS B O   1 
ATOM   7986 C  CB  . CYS B  1 491 ? 23.82998 9.71068   -59.57483 1.000 13.16138 ? 490 CYS B CB  1 
ATOM   7987 S  SG  . CYS B  1 491 ? 24.56291 8.53888   -58.41724 1.000 19.30508 ? 490 CYS B SG  1 
ATOM   7988 N  N   . HIS B  1 492 ? 27.05504 9.49410   -60.38961 1.000 14.50371 ? 491 HIS B N   1 
ATOM   7989 C  CA  . HIS B  1 492 ? 28.15333 8.70583   -60.92829 1.000 15.02335 ? 491 HIS B CA  1 
ATOM   7990 C  C   . HIS B  1 492 ? 28.17863 7.27626   -60.40136 1.000 16.90390 ? 491 HIS B C   1 
ATOM   7991 O  O   . HIS B  1 492 ? 29.16076 6.56239   -60.63094 1.000 16.57033 ? 491 HIS B O   1 
ATOM   7992 C  CB  . HIS B  1 492 ? 29.49111 9.39030   -60.65180 1.000 11.92119 ? 491 HIS B CB  1 
ATOM   7993 C  CG  . HIS B  1 492 ? 30.47419 9.24492   -61.77021 1.000 11.88775 ? 491 HIS B CG  1 
ATOM   7994 N  ND1 . HIS B  1 492 ? 31.18116 8.08326   -61.99321 1.000 13.14246 ? 491 HIS B ND1 1 
ATOM   7995 C  CD2 . HIS B  1 492 ? 30.85564 10.10942  -62.73984 1.000 12.16662 ? 491 HIS B CD2 1 
ATOM   7996 C  CE1 . HIS B  1 492 ? 31.96280 8.24123   -63.04645 1.000 12.87646 ? 491 HIS B CE1 1 
ATOM   7997 N  NE2 . HIS B  1 492 ? 31.78557 9.46245   -63.51690 1.000 14.70931 ? 491 HIS B NE2 1 
ATOM   7998 N  N   . ILE B  1 493 ? 27.13704 6.84556   -59.69588 1.000 17.23931 ? 492 ILE B N   1 
ATOM   7999 C  CA  . ILE B  1 493 ? 26.90788 5.42134   -59.48193 1.000 15.76400 ? 492 ILE B CA  1 
ATOM   8000 C  C   . ILE B  1 493 ? 26.36820 4.87190   -60.79659 1.000 16.08726 ? 492 ILE B C   1 
ATOM   8001 O  O   . ILE B  1 493 ? 25.22393 5.14194   -61.16709 1.000 16.10519 ? 492 ILE B O   1 
ATOM   8002 C  CB  . ILE B  1 493 ? 25.93777 5.16104   -58.32541 1.000 15.21017 ? 492 ILE B CB  1 
ATOM   8003 C  CG1 . ILE B  1 493 ? 26.51594 5.69264   -57.01427 1.000 15.68453 ? 492 ILE B CG1 1 
ATOM   8004 C  CG2 . ILE B  1 493 ? 25.64481 3.67390   -58.20619 1.000 13.12083 ? 492 ILE B CG2 1 
ATOM   8005 C  CD1 . ILE B  1 493 ? 25.58787 5.52962   -55.82887 1.000 17.12929 ? 492 ILE B CD1 1 
ATOM   8006 N  N   . LEU B  1 494 ? 27.20223 4.11706   -61.51515 1.000 17.64808 ? 493 LEU B N   1 
ATOM   8007 C  CA  . LEU B  1 494 ? 26.87593 3.75854   -62.89169 1.000 16.37824 ? 493 LEU B CA  1 
ATOM   8008 C  C   . LEU B  1 494 ? 25.58832 2.95135   -62.98399 1.000 17.61152 ? 493 LEU B C   1 
ATOM   8009 O  O   . LEU B  1 494 ? 24.82813 3.10807   -63.94707 1.000 15.80852 ? 493 LEU B O   1 
ATOM   8010 C  CB  . LEU B  1 494 ? 28.03848 2.99296   -63.51425 1.000 12.09383 ? 493 LEU B CB  1 
ATOM   8011 C  CG  . LEU B  1 494 ? 29.36359 3.75322   -63.49643 1.000 14.60835 ? 493 LEU B CG  1 
ATOM   8012 C  CD1 . LEU B  1 494 ? 30.44379 2.95720   -64.19960 1.000 12.73602 ? 493 LEU B CD1 1 
ATOM   8013 C  CD2 . LEU B  1 494 ? 29.20704 5.13285   -64.11895 1.000 11.17469 ? 493 LEU B CD2 1 
ATOM   8014 N  N   . GLU B  1 495 ? 25.31904 2.09549   -61.99575 1.000 14.87656 ? 494 GLU B N   1 
ATOM   8015 C  CA  . GLU B  1 495 ? 24.06122 1.35808   -61.98959 1.000 15.21573 ? 494 GLU B CA  1 
ATOM   8016 C  C   . GLU B  1 495 ? 22.86859 2.29194   -61.82573 1.000 18.66291 ? 494 GLU B C   1 
ATOM   8017 O  O   . GLU B  1 495 ? 21.75932 1.95845   -62.25758 1.000 19.44152 ? 494 GLU B O   1 
ATOM   8018 C  CB  . GLU B  1 495 ? 24.07458 0.29996   -60.88558 1.000 20.15774 ? 494 GLU B CB  1 
ATOM   8019 C  CG  . GLU B  1 495 ? 24.91998 -0.93030  -61.20385 1.000 17.59608 ? 494 GLU B CG  1 
ATOM   8020 C  CD  . GLU B  1 495 ? 26.41291 -0.64467  -61.21116 1.000 22.35775 ? 494 GLU B CD  1 
ATOM   8021 O  OE1 . GLU B  1 495 ? 26.84315 0.31977   -60.54253 1.000 19.26941 ? 494 GLU B OE1 1 
ATOM   8022 O  OE2 . GLU B  1 495 ? 27.15717 -1.38479  -61.88963 1.000 22.89639 ? 494 GLU B OE2 1 
ATOM   8023 N  N   . HIS B  1 496 ? 23.07479 3.45912   -61.20889 1.000 17.69818 ? 495 HIS B N   1 
ATOM   8024 C  CA  . HIS B  1 496 ? 22.02861 4.47561   -61.15574 1.000 16.53598 ? 495 HIS B CA  1 
ATOM   8025 C  C   . HIS B  1 496 ? 21.96848 5.28153   -62.44699 1.000 14.85563 ? 495 HIS B C   1 
ATOM   8026 O  O   . HIS B  1 496 ? 20.87764 5.59660   -62.93565 1.000 16.03301 ? 495 HIS B O   1 
ATOM   8027 C  CB  . HIS B  1 496 ? 22.25970 5.41670   -59.97189 1.000 19.30313 ? 495 HIS B CB  1 
ATOM   8028 C  CG  . HIS B  1 496 ? 22.11468 4.76117   -58.63466 1.000 18.48341 ? 495 HIS B CG  1 
ATOM   8029 N  ND1 . HIS B  1 496 ? 22.42900 5.40191   -57.45566 1.000 14.01807 ? 495 HIS B ND1 1 
ATOM   8030 C  CD2 . HIS B  1 496 ? 21.68393 3.52589   -58.28813 1.000 17.68280 ? 495 HIS B CD2 1 
ATOM   8031 C  CE1 . HIS B  1 496 ? 22.20354 4.58759   -56.44050 1.000 17.06318 ? 495 HIS B CE1 1 
ATOM   8032 N  NE2 . HIS B  1 496 ? 21.74924 3.44322   -56.91832 1.000 21.65511 ? 495 HIS B NE2 1 
ATOM   8033 N  N   . GLU B  1 497 ? 23.13255 5.62582   -63.00445 1.000 17.62648 ? 496 GLU B N   1 
ATOM   8034 C  CA  . GLU B  1 497 ? 23.17403 6.47300   -64.19157 1.000 14.51338 ? 496 GLU B CA  1 
ATOM   8035 C  C   . GLU B  1 497 ? 22.47088 5.81719   -65.37167 1.000 15.82637 ? 496 GLU B C   1 
ATOM   8036 O  O   . GLU B  1 497 ? 21.74196 6.48289   -66.11558 1.000 16.96551 ? 496 GLU B O   1 
ATOM   8037 C  CB  . GLU B  1 497 ? 24.62423 6.80293   -64.54487 1.000 14.64464 ? 496 GLU B CB  1 
ATOM   8038 C  CG  . GLU B  1 497 ? 24.79810 7.49097   -65.88745 1.000 13.34481 ? 496 GLU B CG  1 
ATOM   8039 C  CD  . GLU B  1 497 ? 26.25387 7.72134   -66.23842 1.000 16.84449 ? 496 GLU B CD  1 
ATOM   8040 O  OE1 . GLU B  1 497 ? 27.11635 7.54802   -65.35178 1.000 17.05188 ? 496 GLU B OE1 1 
ATOM   8041 O  OE2 . GLU B  1 497 ? 26.53698 8.07262   -67.40259 1.000 21.07487 ? 496 GLU B OE2 1 
ATOM   8042 N  N   . ASP B  1 498 ? 22.66407 4.51079   -65.55580 1.000 18.12877 ? 497 ASP B N   1 
ATOM   8043 C  CA  . ASP B  1 498 ? 22.06899 3.84038   -66.70505 1.000 13.96357 ? 497 ASP B CA  1 
ATOM   8044 C  C   . ASP B  1 498 ? 20.55800 3.69717   -66.58896 1.000 18.36631 ? 497 ASP B C   1 
ATOM   8045 O  O   . ASP B  1 498 ? 19.89072 3.47249   -67.60574 1.000 25.29363 ? 497 ASP B O   1 
ATOM   8046 C  CB  . ASP B  1 498 ? 22.71417 2.46388   -66.89628 1.000 16.40699 ? 497 ASP B CB  1 
ATOM   8047 C  CG  . ASP B  1 498 ? 24.12317 2.54707   -67.47525 1.000 19.43058 ? 497 ASP B CG  1 
ATOM   8048 O  OD1 . ASP B  1 498 ? 24.45716 3.57290   -68.10539 1.000 16.70888 ? 497 ASP B OD1 1 
ATOM   8049 O  OD2 . ASP B  1 498 ? 24.89904 1.58147   -67.30613 1.000 18.40774 ? 497 ASP B OD2 1 
ATOM   8050 N  N   . TYR B  1 499 ? 19.99097 3.82432   -65.38976 1.000 19.98252 ? 498 TYR B N   1 
ATOM   8051 C  CA  . TYR B  1 499 ? 18.55926 3.56796   -65.22569 1.000 19.36043 ? 498 TYR B CA  1 
ATOM   8052 C  C   . TYR B  1 499 ? 18.11942 4.19164   -63.89523 1.000 19.51926 ? 498 TYR B C   1 
ATOM   8053 O  O   . TYR B  1 499 ? 18.05959 3.50187   -62.87881 1.000 19.50274 ? 498 TYR B O   1 
ATOM   8054 C  CB  . TYR B  1 499 ? 18.26823 2.07893   -65.27147 1.000 18.29050 ? 498 TYR B CB  1 
ATOM   8055 C  CG  . TYR B  1 499 ? 16.80338 1.72300   -65.42287 1.000 22.69581 ? 498 TYR B CG  1 
ATOM   8056 C  CD1 . TYR B  1 499 ? 16.07026 2.17514   -66.51423 1.000 21.86273 ? 498 TYR B CD1 1 
ATOM   8057 C  CD2 . TYR B  1 499 ? 16.15350 0.93460   -64.47916 1.000 26.42084 ? 498 TYR B CD2 1 
ATOM   8058 C  CE1 . TYR B  1 499 ? 14.73127 1.86147   -66.65547 1.000 22.38339 ? 498 TYR B CE1 1 
ATOM   8059 C  CE2 . TYR B  1 499 ? 14.81546 0.61573   -64.61489 1.000 24.52854 ? 498 TYR B CE2 1 
ATOM   8060 C  CZ  . TYR B  1 499 ? 14.11070 1.08300   -65.70593 1.000 23.98021 ? 498 TYR B CZ  1 
ATOM   8061 O  OH  . TYR B  1 499 ? 12.77946 0.77535   -65.85728 1.000 28.45422 ? 498 TYR B OH  1 
ATOM   8062 N  N   . ASP B  1 500 ? 17.82868 5.49454   -63.91424 1.000 16.75065 ? 499 ASP B N   1 
ATOM   8063 C  CA  . ASP B  1 500 ? 17.95459 6.34460   -65.10250 1.000 19.00721 ? 499 ASP B CA  1 
ATOM   8064 C  C   . ASP B  1 500 ? 18.34631 7.74037   -64.64341 1.000 19.30073 ? 499 ASP B C   1 
ATOM   8065 O  O   . ASP B  1 500 ? 17.80274 8.74131   -65.10902 1.000 17.22530 ? 499 ASP B O   1 
ATOM   8066 C  CB  . ASP B  1 500 ? 16.64499 6.38407   -65.90518 1.000 22.69109 ? 499 ASP B CB  1 
ATOM   8067 C  CG  . ASP B  1 500 ? 16.78685 7.12147   -67.23868 1.000 27.28777 ? 499 ASP B CG  1 
ATOM   8068 O  OD1 . ASP B  1 500 ? 17.75584 6.83059   -67.97387 1.000 30.95054 ? 499 ASP B OD1 1 
ATOM   8069 O  OD2 . ASP B  1 500 ? 15.93463 7.98620   -67.55143 1.000 28.76397 ? 499 ASP B OD2 1 
ATOM   8070 N  N   . MET B  1 501 ? 19.28571 7.79194   -63.70139 1.000 13.79660 ? 500 MET B N   1 
ATOM   8071 C  CA  . MET B  1 501 ? 19.64085 9.04225   -63.04462 1.000 16.18951 ? 500 MET B CA  1 
ATOM   8072 C  C   . MET B  1 501 ? 20.56699 9.89631   -63.89770 1.000 17.69146 ? 500 MET B C   1 
ATOM   8073 O  O   . MET B  1 501 ? 21.63518 10.30165  -63.43197 1.000 20.37519 ? 500 MET B O   1 
ATOM   8074 C  CB  . MET B  1 501 ? 20.30390 8.76235   -61.69599 1.000 17.55445 ? 500 MET B CB  1 
ATOM   8075 C  CG  . MET B  1 501 ? 19.50396 9.22272   -60.49634 1.000 18.74691 ? 500 MET B CG  1 
ATOM   8076 S  SD  . MET B  1 501 ? 20.42681 9.05614   -58.95776 1.000 20.70018 ? 500 MET B SD  1 
ATOM   8077 C  CE  . MET B  1 501 ? 19.10115 9.19191   -57.76158 1.000 23.94235 ? 500 MET B CE  1 
ATOM   8078 N  N   . MET B  1 502 ? 20.17192 10.18560  -65.13530 1.000 16.24335 ? 501 MET B N   1 
ATOM   8079 C  CA  . MET B  1 502 ? 20.97200 11.02130  -66.01998 1.000 17.11364 ? 501 MET B CA  1 
ATOM   8080 C  C   . MET B  1 502 ? 20.04811 11.92236  -66.82318 1.000 18.35412 ? 501 MET B C   1 
ATOM   8081 O  O   . MET B  1 502 ? 19.07035 11.44913  -67.40954 1.000 18.57991 ? 501 MET B O   1 
ATOM   8082 C  CB  . MET B  1 502 ? 21.84016 10.17095  -66.95670 1.000 14.56179 ? 501 MET B CB  1 
ATOM   8083 C  CG  . MET B  1 502 ? 22.83057 10.97833  -67.78756 1.000 15.57918 ? 501 MET B CG  1 
ATOM   8084 S  SD  . MET B  1 502 ? 23.88136 9.93671   -68.81710 1.000 16.40516 ? 501 MET B SD  1 
ATOM   8085 C  CE  . MET B  1 502 ? 22.63888 9.11572   -69.81280 1.000 20.31964 ? 501 MET B CE  1 
ATOM   8086 N  N   . ARG B  1 503 ? 20.36000 13.21370  -66.84722 1.000 18.01516 ? 502 ARG B N   1 
ATOM   8087 C  CA  . ARG B  1 503 ? 19.55646 14.20928  -67.53539 1.000 16.20074 ? 502 ARG B CA  1 
ATOM   8088 C  C   . ARG B  1 503 ? 20.44637 15.10717  -68.38146 1.000 19.17342 ? 502 ARG B C   1 
ATOM   8089 O  O   . ARG B  1 503 ? 21.63321 15.27507  -68.08004 1.000 13.72727 ? 502 ARG B O   1 
ATOM   8090 C  CB  . ARG B  1 503 ? 18.76416 15.06276  -66.53398 1.000 16.78553 ? 502 ARG B CB  1 
ATOM   8091 C  CG  . ARG B  1 503 ? 17.63056 14.32105  -65.84353 1.000 22.83578 ? 502 ARG B CG  1 
ATOM   8092 C  CD  . ARG B  1 503 ? 16.29766 14.97829  -66.15088 1.000 19.97313 ? 502 ARG B CD  1 
ATOM   8093 N  NE  . ARG B  1 503 ? 15.93830 14.84656  -67.55682 1.000 18.59452 ? 502 ARG B NE  1 
ATOM   8094 C  CZ  . ARG B  1 503 ? 15.23565 15.74193  -68.23672 1.000 22.96598 ? 502 ARG B CZ  1 
ATOM   8095 N  NH1 . ARG B  1 503 ? 14.82951 16.87094  -67.67838 1.000 17.07186 ? 502 ARG B NH1 1 
ATOM   8096 N  NH2 . ARG B  1 503 ? 14.94093 15.50284  -69.51161 1.000 26.28296 ? 502 ARG B NH2 1 
ATOM   8097 N  N   . PRO B  1 504 ? 19.90492 15.69101  -69.44821 1.000 16.44163 ? 503 PRO B N   1 
ATOM   8098 C  CA  . PRO B  1 504 ? 20.70959 16.58127  -70.28911 1.000 16.00375 ? 503 PRO B CA  1 
ATOM   8099 C  C   . PRO B  1 504 ? 20.92073 17.94126  -69.64358 1.000 13.28522 ? 503 PRO B C   1 
ATOM   8100 O  O   . PRO B  1 504 ? 20.12159 18.40567  -68.82826 1.000 16.04649 ? 503 PRO B O   1 
ATOM   8101 C  CB  . PRO B  1 504 ? 19.87326 16.70373  -71.56816 1.000 15.25938 ? 503 PRO B CB  1 
ATOM   8102 C  CG  . PRO B  1 504 ? 18.47219 16.51504  -71.10005 1.000 17.16873 ? 503 PRO B CG  1 
ATOM   8103 C  CD  . PRO B  1 504 ? 18.54512 15.50459  -69.98629 1.000 15.21799 ? 503 PRO B CD  1 
ATOM   8104 N  N   . LEU B  1 505 ? 22.02431 18.58028  -70.02845 1.000 14.26081 ? 504 LEU B N   1 
ATOM   8105 C  CA  . LEU B  1 505 ? 22.40021 19.89932  -69.52716 1.000 14.31079 ? 504 LEU B CA  1 
ATOM   8106 C  C   . LEU B  1 505 ? 22.73187 20.78053  -70.72363 1.000 20.50351 ? 504 LEU B C   1 
ATOM   8107 O  O   . LEU B  1 505 ? 23.73389 20.54965  -71.40828 1.000 23.99149 ? 504 LEU B O   1 
ATOM   8108 C  CB  . LEU B  1 505 ? 23.58729 19.80584  -68.56772 1.000 14.53878 ? 504 LEU B CB  1 
ATOM   8109 C  CG  . LEU B  1 505 ? 24.14805 21.11956  -68.02004 1.000 14.17004 ? 504 LEU B CG  1 
ATOM   8110 C  CD1 . LEU B  1 505 ? 23.08288 21.87101  -67.24573 1.000 13.47322 ? 504 LEU B CD1 1 
ATOM   8111 C  CD2 . LEU B  1 505 ? 25.36545 20.86099  -67.14544 1.000 11.45730 ? 504 LEU B CD2 1 
ATOM   8112 N  N   . GLU B  1 506 ? 21.89908 21.78859  -70.97446 1.000 17.89709 ? 505 GLU B N   1 
ATOM   8113 C  CA  . GLU B  1 506 ? 22.01937 22.63747  -72.15584 1.000 19.02087 ? 505 GLU B CA  1 
ATOM   8114 C  C   . GLU B  1 506 ? 22.47791 24.02802  -71.73197 1.000 16.77997 ? 505 GLU B C   1 
ATOM   8115 O  O   . GLU B  1 506 ? 21.74037 24.75133  -71.05591 1.000 18.08079 ? 505 GLU B O   1 
ATOM   8116 C  CB  . GLU B  1 506 ? 20.69224 22.70621  -72.90917 1.000 15.83701 ? 505 GLU B CB  1 
ATOM   8117 C  CG  . GLU B  1 506 ? 20.76478 23.46338  -74.22563 1.000 22.08831 ? 505 GLU B CG  1 
ATOM   8118 C  CD  . GLU B  1 506 ? 21.58692 22.73641  -75.27348 1.000 21.27096 ? 505 GLU B CD  1 
ATOM   8119 O  OE1 . GLU B  1 506 ? 21.70271 21.49587  -75.18612 1.000 29.48666 ? 505 GLU B OE1 1 
ATOM   8120 O  OE2 . GLU B  1 506 ? 22.11976 23.40444  -76.18399 1.000 18.49116 ? 505 GLU B OE2 1 
ATOM   8121 N  N   . VAL B  1 507 ? 23.68830 24.40103  -72.13417 1.000 19.77200 ? 506 VAL B N   1 
ATOM   8122 C  CA  . VAL B  1 507 ? 24.20305 25.74864  -71.91548 1.000 17.62360 ? 506 VAL B CA  1 
ATOM   8123 C  C   . VAL B  1 507 ? 23.89873 26.57359  -73.15947 1.000 17.56476 ? 506 VAL B C   1 
ATOM   8124 O  O   . VAL B  1 507 ? 24.30017 26.20824  -74.26952 1.000 21.40514 ? 506 VAL B O   1 
ATOM   8125 C  CB  . VAL B  1 507 ? 25.70903 25.72999  -71.61460 1.000 17.59969 ? 506 VAL B CB  1 
ATOM   8126 C  CG1 . VAL B  1 507 ? 26.21740 27.14071  -71.35753 1.000 17.95505 ? 506 VAL B CG1 1 
ATOM   8127 C  CG2 . VAL B  1 507 ? 26.00051 24.82762  -70.42366 1.000 16.09884 ? 506 VAL B CG2 1 
ATOM   8128 N  N   . THR B  1 508 ? 23.18777 27.68397  -72.97879 1.000 21.94170 ? 507 THR B N   1 
ATOM   8129 C  CA  . THR B  1 508 ? 22.67002 28.47541  -74.08724 1.000 21.69163 ? 507 THR B CA  1 
ATOM   8130 C  C   . THR B  1 508 ? 23.32267 29.85026  -74.09777 1.000 23.17176 ? 507 THR B C   1 
ATOM   8131 O  O   . THR B  1 508 ? 23.39881 30.51447  -73.05903 1.000 27.97606 ? 507 THR B O   1 
ATOM   8132 C  CB  . THR B  1 508 ? 21.14809 28.61993  -73.99182 1.000 25.73767 ? 507 THR B CB  1 
ATOM   8133 O  OG1 . THR B  1 508 ? 20.56416 27.35393  -73.65842 1.000 22.37473 ? 507 THR B OG1 1 
ATOM   8134 C  CG2 . THR B  1 508 ? 20.57738 29.09602  -75.31655 1.000 26.00209 ? 507 THR B CG2 1 
ATOM   8135 N  N   . ASP B  1 509 ? 23.78363 30.27320  -75.27140 1.000 32.74537 ? 508 ASP B N   1 
ATOM   8136 C  CA  . ASP B  1 509 ? 24.36091 31.59653  -75.45533 1.000 36.72739 ? 508 ASP B CA  1 
ATOM   8137 C  C   . ASP B  1 509 ? 23.26173 32.60991  -75.75344 1.000 38.09493 ? 508 ASP B C   1 
ATOM   8138 O  O   . ASP B  1 509 ? 22.26347 32.29944  -76.40874 1.000 36.85324 ? 508 ASP B O   1 
ATOM   8139 C  CB  . ASP B  1 509 ? 25.38721 31.58259  -76.59357 1.000 37.71089 ? 508 ASP B CB  1 
ATOM   8140 C  CG  . ASP B  1 509 ? 26.25043 32.83886  -76.63413 1.000 40.03043 ? 508 ASP B CG  1 
ATOM   8141 O  OD1 . ASP B  1 509 ? 25.77978 33.92128  -76.22570 1.000 46.15186 ? 508 ASP B OD1 1 
ATOM   8142 O  OD2 . ASP B  1 509 ? 27.41104 32.74176  -77.08576 1.000 41.08019 ? 508 ASP B OD2 1 
ATOM   8143 N  N   . ILE B  1 510 ? 23.45811 33.83235  -75.26208 1.000 44.55401 ? 509 ILE B N   1 
ATOM   8144 C  CA  . ILE B  1 510 ? 22.53242 34.93784  -75.47887 1.000 44.35533 ? 509 ILE B CA  1 
ATOM   8145 C  C   . ILE B  1 510 ? 23.31678 36.12317  -76.02436 1.000 48.34404 ? 509 ILE B C   1 
ATOM   8146 O  O   . ILE B  1 510 ? 24.41771 36.42051  -75.54724 1.000 52.20810 ? 509 ILE B O   1 
ATOM   8147 C  CB  . ILE B  1 510 ? 21.79496 35.33115  -74.18056 1.000 40.93387 ? 509 ILE B CB  1 
ATOM   8148 C  CG1 . ILE B  1 510 ? 21.19047 34.09980  -73.50344 1.000 27.16388 ? 509 ILE B CG1 1 
ATOM   8149 C  CG2 . ILE B  1 510 ? 20.71074 36.35715  -74.47275 1.000 51.20700 ? 509 ILE B CG2 1 
ATOM   8150 C  CD1 . ILE B  1 510 ? 20.09413 33.44016  -74.30275 1.000 32.91922 ? 509 ILE B CD1 1 
ATOM   8151 N  N   . ARG B  1 511 ? 22.75212 36.80176  -77.02491 1.000 63.50433 ? 510 ARG B N   1 
ATOM   8152 C  CA  . ARG B  1 511 ? 23.40056 37.98551  -77.57921 1.000 68.35730 ? 510 ARG B CA  1 
ATOM   8153 C  C   . ARG B  1 511 ? 22.39193 38.92298  -78.23772 1.000 67.67355 ? 510 ARG B C   1 
ATOM   8154 O  O   . ARG B  1 511 ? 22.59235 40.14209  -78.25594 1.000 65.41062 ? 510 ARG B O   1 
ATOM   8155 C  CB  . ARG B  1 511 ? 24.49846 37.57981  -78.57296 1.000 53.75053 ? 510 ARG B CB  1 
ATOM   8156 C  CG  . ARG B  1 511 ? 24.05315 37.37631  -80.02130 1.000 64.21618 ? 510 ARG B CG  1 
ATOM   8157 C  CD  . ARG B  1 511 ? 23.10167 36.19769  -80.18465 1.000 57.55444 ? 510 ARG B CD  1 
ATOM   8158 N  NE  . ARG B  1 511 ? 23.64694 34.96160  -79.63899 1.000 59.70040 ? 510 ARG B NE  1 
ATOM   8159 C  CZ  . ARG B  1 511 ? 24.36893 34.09212  -80.33199 1.000 46.38185 ? 510 ARG B CZ  1 
ATOM   8160 N  NH1 . ARG B  1 511 ? 24.66554 34.29864  -81.60421 1.000 46.89013 ? 510 ARG B NH1 1 
ATOM   8161 N  NH2 . ARG B  1 511 ? 24.80377 32.98731  -79.73357 1.000 46.62276 ? 510 ARG B NH2 1 
ATOM   8162 N  N   . HIS B  1 512 ? 21.30056 38.37005  -78.76775 1.000 57.80477 ? 511 HIS B N   1 
ATOM   8163 C  CA  . HIS B  1 512 ? 20.27844 39.15463  -79.46163 1.000 64.18979 ? 511 HIS B CA  1 
ATOM   8164 C  C   . HIS B  1 512 ? 18.92759 38.55677  -79.08333 1.000 68.40382 ? 511 HIS B C   1 
ATOM   8165 O  O   . HIS B  1 512 ? 18.54407 37.50611  -79.60706 1.000 67.05169 ? 511 HIS B O   1 
ATOM   8166 C  CB  . HIS B  1 512 ? 20.49707 39.14378  -80.97129 1.000 59.77322 ? 511 HIS B CB  1 
ATOM   8167 C  CG  . HIS B  1 512 ? 19.80274 40.25758  -81.69337 1.000 60.46761 ? 511 HIS B CG  1 
ATOM   8168 N  ND1 . HIS B  1 512 ? 18.75380 40.04342  -82.56165 1.000 57.04641 ? 511 HIS B ND1 1 
ATOM   8169 C  CD2 . HIS B  1 512 ? 20.01011 41.59607  -81.67764 1.000 53.92902 ? 511 HIS B CD2 1 
ATOM   8170 C  CE1 . HIS B  1 512 ? 18.34434 41.20143  -83.04880 1.000 54.63124 ? 511 HIS B CE1 1 
ATOM   8171 N  NE2 . HIS B  1 512 ? 19.08959 42.15960  -82.52774 1.000 49.01713 ? 511 HIS B NE2 1 
ATOM   8172 N  N   . GLN B  1 513 ? 18.22626 39.22407  -78.16731 1.000 78.72664 ? 512 GLN B N   1 
ATOM   8173 C  CA  . GLN B  1 513 ? 16.95321 38.75136  -77.61852 1.000 70.79261 ? 512 GLN B CA  1 
ATOM   8174 C  C   . GLN B  1 513 ? 17.11266 37.43045  -76.86600 1.000 51.09561 ? 512 GLN B C   1 
ATOM   8175 O  O   . GLN B  1 513 ? 18.22693 36.95890  -76.63718 1.000 49.53941 ? 512 GLN B O   1 
ATOM   8176 C  CB  . GLN B  1 513 ? 15.90109 38.60889  -78.72666 1.000 58.17970 ? 512 GLN B CB  1 
ATOM   8177 C  CG  . GLN B  1 513 ? 15.11917 37.30127  -78.69545 1.000 49.04360 ? 512 GLN B CG  1 
ATOM   8178 C  CD  . GLN B  1 513 ? 15.76519 36.20161  -79.52513 1.000 51.85099 ? 512 GLN B CD  1 
ATOM   8179 O  OE1 . GLN B  1 513 ? 16.66821 35.50313  -79.06297 1.000 49.65267 ? 512 GLN B OE1 1 
ATOM   8180 N  NE2 . GLN B  1 513 ? 15.29846 36.04195  -80.75759 1.000 51.61560 ? 512 GLN B NE2 1 
HETATM 8181 S  S   . SO4 C  2 .   ? 11.18901 46.18894  -35.65371 1.000 68.24486 ? 601 SO4 A S   1 
HETATM 8182 O  O1  . SO4 C  2 .   ? 11.28665 47.63497  -36.03497 1.000 45.71385 ? 601 SO4 A O1  1 
HETATM 8183 O  O2  . SO4 C  2 .   ? 10.78570 45.37742  -36.84776 1.000 47.95568 ? 601 SO4 A O2  1 
HETATM 8184 O  O3  . SO4 C  2 .   ? 12.52391 45.72227  -35.15947 1.000 39.25131 ? 601 SO4 A O3  1 
HETATM 8185 O  O4  . SO4 C  2 .   ? 10.16965 46.02095  -34.56646 1.000 57.61283 ? 601 SO4 A O4  1 
HETATM 8186 S  S   . SO4 D  2 .   ? 50.98369 27.50693  -15.51995 1.000 46.43008 ? 602 SO4 A S   1 
HETATM 8187 O  O1  . SO4 D  2 .   ? 51.87002 28.59756  -15.00021 1.000 42.88704 ? 602 SO4 A O1  1 
HETATM 8188 O  O2  . SO4 D  2 .   ? 51.82326 26.43270  -16.14058 1.000 39.52235 ? 602 SO4 A O2  1 
HETATM 8189 O  O3  . SO4 D  2 .   ? 50.18837 26.93166  -14.38605 1.000 28.86809 ? 602 SO4 A O3  1 
HETATM 8190 O  O4  . SO4 D  2 .   ? 50.05132 28.06814  -16.55144 1.000 39.03934 ? 602 SO4 A O4  1 
HETATM 8191 S  S   . SO4 E  2 .   ? -0.34676 27.31989  -21.33372 1.000 54.03484 ? 603 SO4 A S   1 
HETATM 8192 O  O1  . SO4 E  2 .   ? 0.41523  27.55965  -22.60149 1.000 44.49819 ? 603 SO4 A O1  1 
HETATM 8193 O  O2  . SO4 E  2 .   ? -1.75861 27.79128  -21.50523 1.000 71.98530 ? 603 SO4 A O2  1 
HETATM 8194 O  O3  . SO4 E  2 .   ? -0.34283 25.85255  -21.02449 1.000 43.16666 ? 603 SO4 A O3  1 
HETATM 8195 O  O4  . SO4 E  2 .   ? 0.29825  28.07395  -20.20795 1.000 38.66397 ? 603 SO4 A O4  1 
HETATM 8196 S  S   . SO4 F  2 .   ? 32.76292 27.99927  -43.26544 1.000 67.98853 ? 604 SO4 A S   1 
HETATM 8197 O  O1  . SO4 F  2 .   ? 32.28479 27.96086  -44.68622 1.000 52.76730 ? 604 SO4 A O1  1 
HETATM 8198 O  O2  . SO4 F  2 .   ? 33.34603 26.66890  -42.89752 1.000 52.74689 ? 604 SO4 A O2  1 
HETATM 8199 O  O3  . SO4 F  2 .   ? 33.81354 29.05975  -43.12317 1.000 44.78200 ? 604 SO4 A O3  1 
HETATM 8200 O  O4  . SO4 F  2 .   ? 31.60994 28.31005  -42.35723 1.000 37.96342 ? 604 SO4 A O4  1 
HETATM 8201 S  S   . SO4 G  2 .   ? 52.24777 34.83173  -34.43323 1.000 80.29072 ? 605 SO4 A S   1 
HETATM 8202 O  O1  . SO4 G  2 .   ? 51.91229 33.53320  -33.76396 1.000 52.65437 ? 605 SO4 A O1  1 
HETATM 8203 O  O2  . SO4 G  2 .   ? 51.82749 34.77877  -35.87101 1.000 52.69607 ? 605 SO4 A O2  1 
HETATM 8204 O  O3  . SO4 G  2 .   ? 51.52505 35.94900  -33.74124 1.000 55.50044 ? 605 SO4 A O3  1 
HETATM 8205 O  O4  . SO4 G  2 .   ? 53.72673 35.06624  -34.35417 1.000 79.36255 ? 605 SO4 A O4  1 
HETATM 8206 S  S   . SO4 H  2 .   ? 13.96000 13.47756  -29.81191 1.000 59.00000 ? 606 SO4 A S   1 
HETATM 8207 O  O1  . SO4 H  2 .   ? 15.19329 14.20857  -30.25351 1.000 36.94277 ? 606 SO4 A O1  1 
HETATM 8208 O  O2  . SO4 H  2 .   ? 13.36722 12.74998  -30.97764 1.000 41.42678 ? 606 SO4 A O2  1 
HETATM 8209 O  O3  . SO4 H  2 .   ? 14.31838 12.47929  -28.74935 1.000 36.63686 ? 606 SO4 A O3  1 
HETATM 8210 O  O4  . SO4 H  2 .   ? 12.95805 14.45759  -29.27457 1.000 38.60854 ? 606 SO4 A O4  1 
HETATM 8211 CU CU  . CU  I  3 .   ? 17.97577 16.00172  -25.43616 1.000 22.25617 ? 607 CU  A CU  1 
HETATM 8212 S  S   . SO4 J  2 .   ? 43.70536 46.39570  -26.13631 1.000 73.47376 ? 608 SO4 A S   1 
HETATM 8213 O  O1  . SO4 J  2 .   ? 42.90516 47.17034  -25.13201 1.000 51.47547 ? 608 SO4 A O1  1 
HETATM 8214 O  O2  . SO4 J  2 .   ? 42.91727 45.20682  -26.59561 1.000 27.00918 ? 608 SO4 A O2  1 
HETATM 8215 O  O3  . SO4 J  2 .   ? 44.01479 47.27687  -27.31005 1.000 53.11837 ? 608 SO4 A O3  1 
HETATM 8216 O  O4  . SO4 J  2 .   ? 44.98571 45.93259  -25.50687 1.000 67.25618 ? 608 SO4 A O4  1 
HETATM 8217 S  S   . SO4 K  2 .   ? 34.08905 41.22571  -18.61069 1.000 84.36627 ? 609 SO4 A S   1 
HETATM 8218 O  O1  . SO4 K  2 .   ? 34.33725 42.70349  -18.55901 1.000 56.97201 ? 609 SO4 A O1  1 
HETATM 8219 O  O2  . SO4 K  2 .   ? 34.32375 40.72931  -20.00608 1.000 42.69199 ? 609 SO4 A O2  1 
HETATM 8220 O  O3  . SO4 K  2 .   ? 35.02432 40.53123  -17.66333 1.000 35.37116 ? 609 SO4 A O3  1 
HETATM 8221 O  O4  . SO4 K  2 .   ? 32.67025 40.94217  -18.21311 1.000 50.34373 ? 609 SO4 A O4  1 
HETATM 8222 S  S   . SO4 L  2 .   ? 4.99014  5.62321   -15.57884 1.000 69.86225 ? 610 SO4 A S   1 
HETATM 8223 O  O1  . SO4 L  2 .   ? 5.28312  5.17153   -16.97752 1.000 46.94094 ? 610 SO4 A O1  1 
HETATM 8224 O  O2  . SO4 L  2 .   ? 4.18223  4.57339   -14.87770 1.000 61.59996 ? 610 SO4 A O2  1 
HETATM 8225 O  O3  . SO4 L  2 .   ? 6.28130  5.83704   -14.84679 1.000 49.16937 ? 610 SO4 A O3  1 
HETATM 8226 O  O4  . SO4 L  2 .   ? 4.21649  6.90776   -15.61382 1.000 45.21025 ? 610 SO4 A O4  1 
HETATM 8227 S  S   . SO4 M  2 .   ? 15.84407 37.60375  5.06027   1.000 84.74528 ? 611 SO4 A S   1 
HETATM 8228 O  O1  . SO4 M  2 .   ? 16.89380 37.97497  4.05682   1.000 54.95295 ? 611 SO4 A O1  1 
HETATM 8229 O  O2  . SO4 M  2 .   ? 14.66936 36.99909  4.35494   1.000 72.56755 ? 611 SO4 A O2  1 
HETATM 8230 O  O3  . SO4 M  2 .   ? 16.41223 36.61125  6.03003   1.000 80.09790 ? 611 SO4 A O3  1 
HETATM 8231 O  O4  . SO4 M  2 .   ? 15.40061 38.82937  5.80097   1.000 85.43841 ? 611 SO4 A O4  1 
HETATM 8232 S  S   . SO4 N  2 .   ? 30.33589 24.25735  5.19511   1.000 44.97912 ? 612 SO4 A S   1 
HETATM 8233 O  O1  . SO4 N  2 .   ? 30.16926 24.45507  3.71978   1.000 36.04995 ? 612 SO4 A O1  1 
HETATM 8234 O  O2  . SO4 N  2 .   ? 29.01927 23.87565  5.80154   1.000 36.66482 ? 612 SO4 A O2  1 
HETATM 8235 O  O3  . SO4 N  2 .   ? 31.33657 23.16692  5.43781   1.000 40.08564 ? 612 SO4 A O3  1 
HETATM 8236 O  O4  . SO4 N  2 .   ? 30.82308 25.53302  5.81602   1.000 53.19261 ? 612 SO4 A O4  1 
HETATM 8237 CU CU  . CU  O  3 .   ? 24.72321 19.32705  -15.47494 1.000 19.11341 ? 613 CU  A CU  1 
HETATM 8238 CU CU  . CU  P  3 .   ? 28.03006 20.77731  -16.14588 1.000 18.48084 ? 614 CU  A CU  1 
HETATM 8239 CU CU  . CU  Q  3 .   ? 25.38782 23.50848  -17.62546 1.000 23.24527 ? 615 CU  A CU  1 
HETATM 8240 S  S   . SO4 R  2 .   ? 40.90503 14.61785  -39.26767 1.000 78.11500 ? 616 SO4 A S   1 
HETATM 8241 O  O1  . SO4 R  2 .   ? 40.19736 15.80371  -39.85082 1.000 55.29179 ? 616 SO4 A O1  1 
HETATM 8242 O  O2  . SO4 R  2 .   ? 42.33165 14.97793  -38.97950 1.000 56.82811 ? 616 SO4 A O2  1 
HETATM 8243 O  O3  . SO4 R  2 .   ? 40.22637 14.21120  -37.99308 1.000 63.74493 ? 616 SO4 A O3  1 
HETATM 8244 O  O4  . SO4 R  2 .   ? 40.85927 13.47981  -40.24385 1.000 34.09577 ? 616 SO4 A O4  1 
HETATM 8245 S  S   . SO4 S  2 .   ? 45.59958 -13.58179 -47.11260 1.000 68.48466 ? 601 SO4 B S   1 
HETATM 8246 O  O1  . SO4 S  2 .   ? 46.92455 -14.27530 -47.01316 1.000 57.87654 ? 601 SO4 B O1  1 
HETATM 8247 O  O2  . SO4 S  2 .   ? 44.88634 -13.67287 -45.79781 1.000 53.07518 ? 601 SO4 B O2  1 
HETATM 8248 O  O3  . SO4 S  2 .   ? 45.82292 -12.14274 -47.46519 1.000 44.15829 ? 601 SO4 B O3  1 
HETATM 8249 O  O4  . SO4 S  2 .   ? 44.76905 -14.23205 -48.17864 1.000 65.35372 ? 601 SO4 B O4  1 
HETATM 8250 S  S   . SO4 T  2 .   ? 49.31508 30.43229  -67.19804 1.000 42.12338 ? 602 SO4 B S   1 
HETATM 8251 O  O1  . SO4 T  2 .   ? 50.61285 30.49128  -67.94407 1.000 43.21219 ? 602 SO4 B O1  1 
HETATM 8252 O  O2  . SO4 T  2 .   ? 49.03699 31.76480  -66.57263 1.000 39.89781 ? 602 SO4 B O2  1 
HETATM 8253 O  O3  . SO4 T  2 .   ? 48.21090 30.08497  -68.15102 1.000 32.53658 ? 602 SO4 B O3  1 
HETATM 8254 O  O4  . SO4 T  2 .   ? 49.39975 29.38599  -66.12756 1.000 41.89061 ? 602 SO4 B O4  1 
HETATM 8255 S  S   . SO4 U  2 .   ? 23.51698 -13.97248 -61.50721 1.000 65.67078 ? 603 SO4 B S   1 
HETATM 8256 O  O1  . SO4 U  2 .   ? 23.59654 -12.72756 -60.67776 1.000 44.56987 ? 603 SO4 B O1  1 
HETATM 8257 O  O2  . SO4 U  2 .   ? 23.90340 -15.15391 -60.67011 1.000 71.83343 ? 603 SO4 B O2  1 
HETATM 8258 O  O3  . SO4 U  2 .   ? 22.11126 -14.14651 -62.00111 1.000 46.88401 ? 603 SO4 B O3  1 
HETATM 8259 O  O4  . SO4 U  2 .   ? 24.45305 -13.86116 -62.67488 1.000 38.77182 ? 603 SO4 B O4  1 
HETATM 8260 S  S   . SO4 V  2 .   ? 56.50217 27.57303  -48.01553 1.000 83.11023 ? 604 SO4 B S   1 
HETATM 8261 O  O1  . SO4 V  2 .   ? 55.45016 27.55301  -49.08256 1.000 44.69363 ? 604 SO4 B O1  1 
HETATM 8262 O  O2  . SO4 V  2 .   ? 55.85372 27.45427  -46.66946 1.000 53.98974 ? 604 SO4 B O2  1 
HETATM 8263 O  O3  . SO4 V  2 .   ? 57.44611 26.42492  -48.21976 1.000 59.16094 ? 604 SO4 B O3  1 
HETATM 8264 O  O4  . SO4 V  2 .   ? 57.26003 28.86427  -48.09288 1.000 84.74963 ? 604 SO4 B O4  1 
HETATM 8265 S  S   . SO4 W  2 .   ? 18.53936 5.44005   -52.53457 1.000 49.57683 ? 605 SO4 B S   1 
HETATM 8266 O  O1  . SO4 W  2 .   ? 19.53549 6.39914   -51.95486 1.000 36.01824 ? 605 SO4 B O1  1 
HETATM 8267 O  O2  . SO4 W  2 .   ? 17.66460 4.90484   -51.44110 1.000 41.70541 ? 605 SO4 B O2  1 
HETATM 8268 O  O3  . SO4 W  2 .   ? 17.69433 6.15534   -53.54654 1.000 40.75866 ? 605 SO4 B O3  1 
HETATM 8269 O  O4  . SO4 W  2 .   ? 19.26286 4.30663   -53.19818 1.000 33.32752 ? 605 SO4 B O4  1 
HETATM 8270 CU CU  . CU  X  3 .   ? 22.73004 7.55257   -57.29152 1.000 24.78632 ? 606 CU  B CU  1 
HETATM 8271 S  S   . SO4 Y  2 .   ? 61.86699 14.77733  -56.41240 1.000 63.37840 ? 607 SO4 B S   1 
HETATM 8272 O  O1  . SO4 Y  2 .   ? 62.41437 13.62884  -57.20666 1.000 38.75673 ? 607 SO4 B O1  1 
HETATM 8273 O  O2  . SO4 Y  2 .   ? 60.39447 14.58977  -56.20617 1.000 28.00212 ? 607 SO4 B O2  1 
HETATM 8274 O  O3  . SO4 Y  2 .   ? 62.55993 14.83447  -55.08352 1.000 41.79742 ? 607 SO4 B O3  1 
HETATM 8275 O  O4  . SO4 Y  2 .   ? 62.10443 16.05873  -57.15490 1.000 62.85566 ? 607 SO4 B O4  1 
HETATM 8276 S  S   . SO4 Z  2 .   ? 52.48124 9.02096   -64.02272 1.000 85.62627 ? 608 SO4 B S   1 
HETATM 8277 O  O1  . SO4 Z  2 .   ? 53.83154 8.37422   -63.93353 1.000 46.97415 ? 608 SO4 B O1  1 
HETATM 8278 O  O2  . SO4 Z  2 .   ? 52.11219 9.60523   -62.69004 1.000 37.57491 ? 608 SO4 B O2  1 
HETATM 8279 O  O3  . SO4 Z  2 .   ? 52.51566 10.10530  -65.06100 1.000 37.71078 ? 608 SO4 B O3  1 
HETATM 8280 O  O4  . SO4 Z  2 .   ? 51.46358 7.99185   -64.41436 1.000 37.25408 ? 608 SO4 B O4  1 
HETATM 8281 S  S   . SO4 AA 2 .   ? 26.41947 -5.60588  -48.91804 1.000 52.52400 ? 609 SO4 B S   1 
HETATM 8282 O  O1  . SO4 AA 2 .   ? 27.88142 -5.83784  -48.68599 1.000 45.05236 ? 609 SO4 B O1  1 
HETATM 8283 O  O2  . SO4 AA 2 .   ? 25.62387 -6.53830  -48.05608 1.000 42.55833 ? 609 SO4 B O2  1 
HETATM 8284 O  O3  . SO4 AA 2 .   ? 26.07714 -4.18923  -48.56770 1.000 38.56277 ? 609 SO4 B O3  1 
HETATM 8285 O  O4  . SO4 AA 2 .   ? 26.09570 -5.85662  -50.36060 1.000 48.62586 ? 609 SO4 B O4  1 
HETATM 8286 S  S   . SO4 BA 2 .   ? 7.56458  1.74773   -67.04875 1.000 67.82151 ? 610 SO4 B S   1 
HETATM 8287 O  O1  . SO4 BA 2 .   ? 6.69056  2.14711   -65.89813 1.000 48.82903 ? 610 SO4 B O1  1 
HETATM 8288 O  O2  . SO4 BA 2 .   ? 7.15537  2.50133   -68.27695 1.000 57.60629 ? 610 SO4 B O2  1 
HETATM 8289 O  O3  . SO4 BA 2 .   ? 8.99298  2.06874   -66.72456 1.000 56.54646 ? 610 SO4 B O3  1 
HETATM 8290 O  O4  . SO4 BA 2 .   ? 7.42379  0.27559   -67.29614 1.000 44.66227 ? 610 SO4 B O4  1 
HETATM 8291 S  S   . SO4 CA 2 .   ? 40.86717 -5.36538  -87.42073 1.000 95.28502 ? 611 SO4 B S   1 
HETATM 8292 O  O1  . SO4 CA 2 .   ? 41.52076 -4.03105  -87.22337 1.000 64.15575 ? 611 SO4 B O1  1 
HETATM 8293 O  O2  . SO4 CA 2 .   ? 39.52424 -5.36404  -86.75909 1.000 68.85560 ? 611 SO4 B O2  1 
HETATM 8294 O  O3  . SO4 CA 2 .   ? 40.69934 -5.63122  -88.88700 1.000 62.40795 ? 611 SO4 B O3  1 
HETATM 8295 O  O4  . SO4 CA 2 .   ? 41.72076 -6.43669  -86.81061 1.000 94.54088 ? 611 SO4 B O4  1 
HETATM 8296 S  S   . SO4 DA 2 .   ? 36.36226 14.08950  -87.95826 1.000 50.91128 ? 612 SO4 B S   1 
HETATM 8297 O  O1  . SO4 DA 2 .   ? 36.72483 14.07163  -86.50338 1.000 32.20189 ? 612 SO4 B O1  1 
HETATM 8298 O  O2  . SO4 DA 2 .   ? 35.18773 13.18888  -88.19825 1.000 33.20130 ? 612 SO4 B O2  1 
HETATM 8299 O  O3  . SO4 DA 2 .   ? 36.00948 15.49006  -88.36069 1.000 36.41628 ? 612 SO4 B O3  1 
HETATM 8300 O  O4  . SO4 DA 2 .   ? 37.53156 13.61263  -88.76831 1.000 44.87889 ? 612 SO4 B O4  1 
HETATM 8301 CU CU  . CU  EA 3 .   ? 29.13789 11.79620  -67.27847 1.000 21.75916 ? 613 CU  B CU  1 
HETATM 8302 CU CU  . CU  FA 3 .   ? 32.01762 13.79958  -66.53525 1.000 19.54016 ? 614 CU  B CU  1 
HETATM 8303 CU CU  . CU  GA 3 .   ? 32.91517 10.26636  -65.18212 1.000 23.61401 ? 615 CU  B CU  1 
HETATM 8304 O  O   . HOH HA 4 .   ? 5.71465  32.38048  -1.88805  1.000 27.70697 ? 701 HOH A O   1 
HETATM 8305 O  O   . HOH HA 4 .   ? 35.05236 38.89394  -21.06057 1.000 29.84960 ? 702 HOH A O   1 
HETATM 8306 O  O   . HOH HA 4 .   ? 16.75934 -0.90980  -11.84008 1.000 30.61055 ? 703 HOH A O   1 
HETATM 8307 O  O   . HOH HA 4 .   ? 2.61016  38.86919  -13.16158 1.000 31.51970 ? 704 HOH A O   1 
HETATM 8308 O  O   . HOH HA 4 .   ? 46.62070 34.94491  -14.84587 1.000 28.27059 ? 705 HOH A O   1 
HETATM 8309 O  O   . HOH HA 4 .   ? 50.75796 41.20101  -32.40561 1.000 35.18383 ? 706 HOH A O   1 
HETATM 8310 O  O   . HOH HA 4 .   ? 14.06656 47.35935  -35.62002 1.000 33.92796 ? 707 HOH A O   1 
HETATM 8311 O  O   . HOH HA 4 .   ? 49.51733 25.15153  -23.72650 1.000 35.39931 ? 708 HOH A O   1 
HETATM 8312 O  O   . HOH HA 4 .   ? 9.29526  22.62241  -6.20207  1.000 35.65270 ? 709 HOH A O   1 
HETATM 8313 O  O   . HOH HA 4 .   ? 50.55653 48.48275  -37.64699 1.000 32.90797 ? 710 HOH A O   1 
HETATM 8314 O  O   . HOH HA 4 .   ? 24.03021 42.60714  -7.95152  1.000 29.19724 ? 711 HOH A O   1 
HETATM 8315 O  O   . HOH HA 4 .   ? 45.36505 15.33069  -27.53913 1.000 42.26286 ? 712 HOH A O   1 
HETATM 8316 O  O   . HOH HA 4 .   ? 6.24988  21.03331  0.96491   1.000 54.21930 ? 713 HOH A O   1 
HETATM 8317 O  O   . HOH HA 4 .   ? 47.34146 14.47319  -25.09037 1.000 34.68964 ? 714 HOH A O   1 
HETATM 8318 O  O   . HOH HA 4 .   ? 10.09888 39.84451  -37.62769 1.000 28.90262 ? 715 HOH A O   1 
HETATM 8319 O  O   . HOH HA 4 .   ? 20.04857 26.74828  -46.09723 1.000 26.17968 ? 716 HOH A O   1 
HETATM 8320 O  O   . HOH HA 4 .   ? 17.55169 32.21663  -18.09583 1.000 21.38834 ? 717 HOH A O   1 
HETATM 8321 O  O   . HOH HA 4 .   ? 40.70210 21.59901  -10.13108 1.000 15.79147 ? 718 HOH A O   1 
HETATM 8322 O  O   . HOH HA 4 .   ? 32.56607 25.23764  -28.31308 1.000 12.40899 ? 719 HOH A O   1 
HETATM 8323 O  O   . HOH HA 4 .   ? 43.61499 33.90115  -3.16562  1.000 25.53869 ? 720 HOH A O   1 
HETATM 8324 O  O   . HOH HA 4 .   ? 43.25267 44.26996  -37.44405 1.000 27.96746 ? 721 HOH A O   1 
HETATM 8325 O  O   . HOH HA 4 .   ? 28.46500 55.69496  -31.67542 1.000 30.82259 ? 722 HOH A O   1 
HETATM 8326 O  O   . HOH HA 4 .   ? 31.97157 32.65532  -19.32409 1.000 17.38202 ? 723 HOH A O   1 
HETATM 8327 O  O   . HOH HA 4 .   ? 34.71031 1.33686   -15.40995 1.000 14.11435 ? 724 HOH A O   1 
HETATM 8328 O  O   . HOH HA 4 .   ? 39.66159 33.00300  -20.55175 1.000 15.58158 ? 725 HOH A O   1 
HETATM 8329 O  O   . HOH HA 4 .   ? 5.32057  22.84209  -18.90949 1.000 24.17395 ? 726 HOH A O   1 
HETATM 8330 O  O   . HOH HA 4 .   ? 52.09829 32.48232  -9.29486  1.000 32.29200 ? 727 HOH A O   1 
HETATM 8331 O  O   . HOH HA 4 .   ? 33.06009 46.20543  -23.64471 1.000 20.37806 ? 728 HOH A O   1 
HETATM 8332 O  O   . HOH HA 4 .   ? 15.92480 31.93645  -21.90495 1.000 22.83649 ? 729 HOH A O   1 
HETATM 8333 O  O   . HOH HA 4 .   ? 46.15089 43.25524  -25.36381 1.000 32.58932 ? 730 HOH A O   1 
HETATM 8334 O  O   . HOH HA 4 .   ? 38.43788 35.52391  -8.19672  1.000 12.94287 ? 731 HOH A O   1 
HETATM 8335 O  O   . HOH HA 4 .   ? 6.30495  22.79686  -15.63544 1.000 22.25154 ? 732 HOH A O   1 
HETATM 8336 O  O   . HOH HA 4 .   ? 28.68197 15.63827  -6.79332  1.000 14.29183 ? 733 HOH A O   1 
HETATM 8337 O  O   . HOH HA 4 .   ? 18.65500 34.40276  -41.16472 1.000 26.58814 ? 734 HOH A O   1 
HETATM 8338 O  O   . HOH HA 4 .   ? 36.58259 50.75281  -41.82566 1.000 33.48630 ? 735 HOH A O   1 
HETATM 8339 O  O   . HOH HA 4 .   ? 22.42935 45.09158  -40.36514 1.000 23.79081 ? 736 HOH A O   1 
HETATM 8340 O  O   . HOH HA 4 .   ? 18.16755 43.70938  -18.64628 1.000 24.03990 ? 737 HOH A O   1 
HETATM 8341 O  O   . HOH HA 4 .   ? 25.18327 24.74548  -0.23684  1.000 19.30912 ? 738 HOH A O   1 
HETATM 8342 O  O   . HOH HA 4 .   ? 16.14261 16.73990  -36.91781 1.000 24.92202 ? 739 HOH A O   1 
HETATM 8343 O  O   . HOH HA 4 .   ? -0.76902 18.90112  -26.60643 1.000 40.40876 ? 740 HOH A O   1 
HETATM 8344 O  O   . HOH HA 4 .   ? 25.12381 6.09653   -14.77163 1.000 17.26514 ? 741 HOH A O   1 
HETATM 8345 O  O   . HOH HA 4 .   ? 24.97034 22.47201  -2.06568  1.000 17.90535 ? 742 HOH A O   1 
HETATM 8346 O  O   . HOH HA 4 .   ? 49.65216 29.38710  -18.63312 1.000 27.99465 ? 743 HOH A O   1 
HETATM 8347 O  O   . HOH HA 4 .   ? 47.47109 37.31464  2.39282   1.000 25.35964 ? 744 HOH A O   1 
HETATM 8348 O  O   . HOH HA 4 .   ? 10.89484 26.70798  -1.51227  1.000 30.73272 ? 745 HOH A O   1 
HETATM 8349 O  O   . HOH HA 4 .   ? 5.70314  24.44001  -1.79938  1.000 34.86447 ? 746 HOH A O   1 
HETATM 8350 O  O   . HOH HA 4 .   ? 38.79980 17.02441  -15.43464 1.000 25.09622 ? 747 HOH A O   1 
HETATM 8351 O  O   . HOH HA 4 .   ? 30.41256 46.67961  -25.39797 1.000 16.19374 ? 748 HOH A O   1 
HETATM 8352 O  O   . HOH HA 4 .   ? 29.05057 20.11397  -30.61596 1.000 8.79767  ? 749 HOH A O   1 
HETATM 8353 O  O   . HOH HA 4 .   ? 40.74634 30.33636  -22.92513 1.000 14.65048 ? 750 HOH A O   1 
HETATM 8354 O  O   . HOH HA 4 .   ? 40.89717 39.14731  -23.75590 1.000 17.08806 ? 751 HOH A O   1 
HETATM 8355 O  O   . HOH HA 4 .   ? 26.02080 36.32945  4.20356   1.000 30.42214 ? 752 HOH A O   1 
HETATM 8356 O  O   . HOH HA 4 .   ? 42.20950 46.62808  -35.92959 1.000 24.44513 ? 753 HOH A O   1 
HETATM 8357 O  O   . HOH HA 4 .   ? 21.00657 35.82220  -12.28867 1.000 16.55792 ? 754 HOH A O   1 
HETATM 8358 O  O   . HOH HA 4 .   ? 37.00435 18.09760  -29.76253 1.000 10.47302 ? 755 HOH A O   1 
HETATM 8359 O  O   . HOH HA 4 .   ? 10.91099 43.52780  -18.91343 1.000 23.63769 ? 756 HOH A O   1 
HETATM 8360 O  O   . HOH HA 4 .   ? 17.48220 31.36918  -42.40611 1.000 24.88849 ? 757 HOH A O   1 
HETATM 8361 O  O   . HOH HA 4 .   ? 17.15488 22.14313  -29.71437 1.000 24.02916 ? 758 HOH A O   1 
HETATM 8362 O  O   . HOH HA 4 .   ? 3.43692  32.02474  -18.15343 1.000 29.76717 ? 759 HOH A O   1 
HETATM 8363 O  O   . HOH HA 4 .   ? 20.88729 36.85359  -22.15798 1.000 15.25493 ? 760 HOH A O   1 
HETATM 8364 O  O   . HOH HA 4 .   ? 25.46192 30.41474  -45.53651 1.000 29.51402 ? 761 HOH A O   1 
HETATM 8365 O  O   . HOH HA 4 .   ? 16.31340 45.39321  -10.79055 1.000 23.45539 ? 762 HOH A O   1 
HETATM 8366 O  O   . HOH HA 4 .   ? 18.13520 9.02244   -18.63835 1.000 15.34523 ? 763 HOH A O   1 
HETATM 8367 O  O   . HOH HA 4 .   ? 2.37463  30.01513  -17.90669 1.000 28.58075 ? 764 HOH A O   1 
HETATM 8368 O  O   . HOH HA 4 .   ? 25.41117 18.17469  -10.65100 1.000 17.43222 ? 765 HOH A O   1 
HETATM 8369 O  O   . HOH HA 4 .   ? 29.37366 24.43337  -8.55154  1.000 9.91358  ? 766 HOH A O   1 
HETATM 8370 O  O   . HOH HA 4 .   ? 42.99180 27.08993  -22.59250 1.000 15.57029 ? 767 HOH A O   1 
HETATM 8371 O  O   . HOH HA 4 .   ? 25.68208 27.17143  -1.11432  1.000 17.61159 ? 768 HOH A O   1 
HETATM 8372 O  O   . HOH HA 4 .   ? 8.50023  36.84359  -14.92537 1.000 21.35495 ? 769 HOH A O   1 
HETATM 8373 O  O   . HOH HA 4 .   ? 18.92267 18.77620  -12.88231 1.000 14.16653 ? 770 HOH A O   1 
HETATM 8374 O  O   . HOH HA 4 .   ? 9.93945  42.46369  -33.19675 1.000 29.02504 ? 771 HOH A O   1 
HETATM 8375 O  O   . HOH HA 4 .   ? 7.07091  33.80192  -0.02291  1.000 34.84805 ? 772 HOH A O   1 
HETATM 8376 O  O   . HOH HA 4 .   ? 31.66076 22.36152  -11.09303 1.000 9.84146  ? 773 HOH A O   1 
HETATM 8377 O  O   . HOH HA 4 .   ? 33.17544 25.28748  -31.24736 1.000 17.28400 ? 774 HOH A O   1 
HETATM 8378 O  O   . HOH HA 4 .   ? 27.85603 2.34803   -19.18095 1.000 15.01953 ? 775 HOH A O   1 
HETATM 8379 O  O   . HOH HA 4 .   ? 37.16737 2.93057   -16.67217 1.000 15.18339 ? 776 HOH A O   1 
HETATM 8380 O  O   . HOH HA 4 .   ? 39.76065 20.44591  -17.05614 1.000 24.64906 ? 777 HOH A O   1 
HETATM 8381 O  O   . HOH HA 4 .   ? 15.38341 29.29592  -23.12910 1.000 17.23476 ? 778 HOH A O   1 
HETATM 8382 O  O   . HOH HA 4 .   ? 20.19511 24.46646  -21.19956 1.000 17.90044 ? 779 HOH A O   1 
HETATM 8383 O  O   . HOH HA 4 .   ? 15.23006 41.46007  -4.28075  1.000 18.68112 ? 780 HOH A O   1 
HETATM 8384 O  O   . HOH HA 4 .   ? 35.41597 37.98792  -9.62461  1.000 17.44987 ? 781 HOH A O   1 
HETATM 8385 O  O   . HOH HA 4 .   ? 14.77883 2.97954   -16.02389 1.000 27.05018 ? 782 HOH A O   1 
HETATM 8386 O  O   . HOH HA 4 .   ? 27.67933 37.01927  -15.74166 1.000 16.35729 ? 783 HOH A O   1 
HETATM 8387 O  O   . HOH HA 4 .   ? 24.24815 41.61939  -14.79679 1.000 23.61965 ? 784 HOH A O   1 
HETATM 8388 O  O   . HOH HA 4 .   ? 14.23269 37.23648  -2.86330  1.000 24.45139 ? 785 HOH A O   1 
HETATM 8389 O  O   . HOH HA 4 .   ? 17.22580 28.71334  -33.43535 1.000 16.30847 ? 786 HOH A O   1 
HETATM 8390 O  O   . HOH HA 4 .   ? 23.90298 2.91015   -46.48609 1.000 21.04276 ? 787 HOH A O   1 
HETATM 8391 O  O   . HOH HA 4 .   ? 16.52012 17.48065  -12.89639 1.000 16.50380 ? 788 HOH A O   1 
HETATM 8392 O  O   . HOH HA 4 .   ? 33.91403 49.27310  -27.31478 1.000 22.11871 ? 789 HOH A O   1 
HETATM 8393 O  O   . HOH HA 4 .   ? 18.44314 43.60234  -11.41743 1.000 17.47183 ? 790 HOH A O   1 
HETATM 8394 O  O   . HOH HA 4 .   ? 37.49328 41.44585  -17.08634 1.000 31.07337 ? 791 HOH A O   1 
HETATM 8395 O  O   . HOH HA 4 .   ? 32.14831 19.71627  -13.37242 1.000 10.37056 ? 792 HOH A O   1 
HETATM 8396 O  O   . HOH HA 4 .   ? 40.11012 23.59732  -26.64985 1.000 10.26394 ? 793 HOH A O   1 
HETATM 8397 O  O   . HOH HA 4 .   ? 4.94929  41.70295  -6.68027  1.000 36.15545 ? 794 HOH A O   1 
HETATM 8398 O  O   . HOH HA 4 .   ? 16.15259 16.61036  -29.47300 1.000 19.49715 ? 795 HOH A O   1 
HETATM 8399 O  O   . HOH HA 4 .   ? 17.70220 25.14775  -33.40505 1.000 14.13541 ? 796 HOH A O   1 
HETATM 8400 O  O   . HOH HA 4 .   ? 46.49774 18.25673  -29.28428 1.000 42.27001 ? 797 HOH A O   1 
HETATM 8401 O  O   . HOH HA 4 .   ? 28.82896 -1.65505  -30.33871 1.000 23.97545 ? 798 HOH A O   1 
HETATM 8402 O  O   . HOH HA 4 .   ? 30.22904 45.12741  -46.39149 1.000 28.75873 ? 799 HOH A O   1 
HETATM 8403 O  O   . HOH HA 4 .   ? 16.46601 46.64063  -27.58916 1.000 20.71712 ? 800 HOH A O   1 
HETATM 8404 O  O   . HOH HA 4 .   ? 16.48854 24.12098  -31.48833 1.000 18.00215 ? 801 HOH A O   1 
HETATM 8405 O  O   . HOH HA 4 .   ? 7.11483  37.18596  -26.05069 1.000 20.73908 ? 802 HOH A O   1 
HETATM 8406 O  O   . HOH HA 4 .   ? 42.77713 20.95594  -36.26005 1.000 42.20106 ? 803 HOH A O   1 
HETATM 8407 O  O   . HOH HA 4 .   ? 36.59531 20.59564  -16.90241 1.000 13.91989 ? 804 HOH A O   1 
HETATM 8408 O  O   . HOH HA 4 .   ? 27.39613 16.80488  -9.47318  1.000 17.48272 ? 805 HOH A O   1 
HETATM 8409 O  O   . HOH HA 4 .   ? 20.72608 29.70018  1.80958   1.000 22.00456 ? 806 HOH A O   1 
HETATM 8410 O  O   . HOH HA 4 .   ? 45.09858 24.84251  -1.36797  1.000 54.39889 ? 807 HOH A O   1 
HETATM 8411 O  O   . HOH HA 4 .   ? 23.31192 6.61490   -43.94492 1.000 16.20405 ? 808 HOH A O   1 
HETATM 8412 O  O   . HOH HA 4 .   ? 11.17438 30.63505  -35.86361 1.000 25.62764 ? 809 HOH A O   1 
HETATM 8413 O  O   . HOH HA 4 .   ? 47.31570 24.81037  -22.45077 1.000 32.03989 ? 810 HOH A O   1 
HETATM 8414 O  O   . HOH HA 4 .   ? 10.52530 14.17776  -27.96314 1.000 19.96091 ? 811 HOH A O   1 
HETATM 8415 O  O   . HOH HA 4 .   ? 8.70060  20.31140  -12.47250 1.000 16.17702 ? 812 HOH A O   1 
HETATM 8416 O  O   . HOH HA 4 .   ? 47.60534 8.39569   -20.12077 1.000 64.06791 ? 813 HOH A O   1 
HETATM 8417 O  O   . HOH HA 4 .   ? 2.66971  35.78832  -15.62340 1.000 32.60432 ? 814 HOH A O   1 
HETATM 8418 O  O   . HOH HA 4 .   ? -4.62126 24.46703  -24.60780 1.000 35.11159 ? 815 HOH A O   1 
HETATM 8419 O  O   . HOH HA 4 .   ? 17.72116 19.83470  -30.71060 1.000 11.22637 ? 816 HOH A O   1 
HETATM 8420 O  O   . HOH HA 4 .   ? 5.36761  10.93536  -14.09690 1.000 22.26217 ? 817 HOH A O   1 
HETATM 8421 O  O   . HOH HA 4 .   ? 39.59221 41.07509  -20.26549 1.000 18.45364 ? 818 HOH A O   1 
HETATM 8422 O  O   . HOH HA 4 .   ? 25.21244 45.28120  -16.35893 1.000 15.17168 ? 819 HOH A O   1 
HETATM 8423 O  O   . HOH HA 4 .   ? 42.32836 4.74351   -10.02841 1.000 24.60476 ? 820 HOH A O   1 
HETATM 8424 O  O   . HOH HA 4 .   ? 7.57778  21.15215  -5.21669  1.000 28.66094 ? 821 HOH A O   1 
HETATM 8425 O  O   . HOH HA 4 .   ? 35.371   25.973    3.421     1.000 35.66508 ? 822 HOH A O   1 
HETATM 8426 O  O   . HOH HA 4 .   ? 29.52392 35.62394  -40.60420 1.000 21.19455 ? 823 HOH A O   1 
HETATM 8427 O  O   . HOH HA 4 .   ? 24.84798 25.53488  -4.42425  1.000 14.43365 ? 824 HOH A O   1 
HETATM 8428 O  O   . HOH HA 4 .   ? 31.10886 7.72170   -34.59567 1.000 15.63206 ? 825 HOH A O   1 
HETATM 8429 O  O   . HOH HA 4 .   ? 20.90761 31.78845  3.06520   1.000 28.37804 ? 826 HOH A O   1 
HETATM 8430 O  O   . HOH HA 4 .   ? 28.24405 -1.61883  -39.01197 1.000 20.01830 ? 827 HOH A O   1 
HETATM 8431 O  O   . HOH HA 4 .   ? 26.57845 1.42510   -21.40881 1.000 14.99649 ? 828 HOH A O   1 
HETATM 8432 O  O   . HOH HA 4 .   ? 39.32526 16.96526  -18.20213 1.000 30.84052 ? 829 HOH A O   1 
HETATM 8433 O  O   . HOH HA 4 .   ? 20.63233 8.91264   -9.34808  1.000 20.38925 ? 830 HOH A O   1 
HETATM 8434 O  O   . HOH HA 4 .   ? 24.53313 -0.84453  -43.78535 1.000 20.68005 ? 831 HOH A O   1 
HETATM 8435 O  O   . HOH HA 4 .   ? 4.16099  14.17474  -6.01608  1.000 35.76544 ? 832 HOH A O   1 
HETATM 8436 O  O   . HOH HA 4 .   ? 33.11677 2.99127   -27.80525 1.000 18.03129 ? 833 HOH A O   1 
HETATM 8437 O  O   . HOH HA 4 .   ? 27.59456 19.08016  -1.63266  1.000 23.41986 ? 834 HOH A O   1 
HETATM 8438 O  O   . HOH HA 4 .   ? 33.13927 44.09555  -22.01494 1.000 21.64809 ? 835 HOH A O   1 
HETATM 8439 O  O   . HOH HA 4 .   ? 42.31049 24.48969  -22.22297 1.000 21.26661 ? 836 HOH A O   1 
HETATM 8440 O  O   . HOH HA 4 .   ? 30.99859 20.34589  -15.68333 1.000 15.78086 ? 837 HOH A O   1 
HETATM 8441 O  O   . HOH HA 4 .   ? 44.17315 21.55555  -33.26984 1.000 33.43432 ? 838 HOH A O   1 
HETATM 8442 O  O   . HOH HA 4 .   ? 5.06277  20.19833  -1.97327  1.000 33.09997 ? 839 HOH A O   1 
HETATM 8443 O  O   . HOH HA 4 .   ? 40.40671 10.03175  -4.50177  1.000 34.10096 ? 840 HOH A O   1 
HETATM 8444 O  O   . HOH HA 4 .   ? 10.83382 28.85427  -30.94024 1.000 30.80203 ? 841 HOH A O   1 
HETATM 8445 O  O   . HOH HA 4 .   ? 31.02831 3.36096   -32.19041 1.000 12.14125 ? 842 HOH A O   1 
HETATM 8446 O  O   . HOH HA 4 .   ? 30.70397 42.96471  -6.36247  1.000 23.36072 ? 843 HOH A O   1 
HETATM 8447 O  O   . HOH HA 4 .   ? 36.82020 41.41559  -8.64114  1.000 24.07777 ? 844 HOH A O   1 
HETATM 8448 O  O   . HOH HA 4 .   ? 23.54549 1.47133   -27.14348 1.000 31.65209 ? 845 HOH A O   1 
HETATM 8449 O  O   . HOH HA 4 .   ? 32.26544 44.14676  -16.34322 1.000 23.91656 ? 846 HOH A O   1 
HETATM 8450 O  O   . HOH HA 4 .   ? 8.09864  22.09945  -18.96499 1.000 19.08865 ? 847 HOH A O   1 
HETATM 8451 O  O   . HOH HA 4 .   ? 50.33035 31.05215  -9.80269  1.000 27.29118 ? 848 HOH A O   1 
HETATM 8452 O  O   . HOH HA 4 .   ? 43.59601 22.04337  -17.66118 1.000 29.58603 ? 849 HOH A O   1 
HETATM 8453 O  O   . HOH HA 4 .   ? 1.91585  18.79025  -11.51531 1.000 29.03264 ? 850 HOH A O   1 
HETATM 8454 O  O   . HOH HA 4 .   ? 13.22450 28.70565  -1.27703  1.000 25.81434 ? 851 HOH A O   1 
HETATM 8455 O  O   . HOH HA 4 .   ? 10.73408 53.29997  -35.43646 1.000 23.23138 ? 852 HOH A O   1 
HETATM 8456 O  O   . HOH HA 4 .   ? 25.94161 43.13856  -13.19176 1.000 20.95627 ? 853 HOH A O   1 
HETATM 8457 O  O   . HOH HA 4 .   ? 41.93805 49.65134  -36.33108 1.000 24.10951 ? 854 HOH A O   1 
HETATM 8458 O  O   . HOH HA 4 .   ? 10.65802 30.13946  -38.10620 1.000 28.36325 ? 855 HOH A O   1 
HETATM 8459 O  O   . HOH HA 4 .   ? 30.77066 38.15528  -3.53870  1.000 23.07528 ? 856 HOH A O   1 
HETATM 8460 O  O   . HOH HA 4 .   ? 22.28508 26.97015  8.22544   1.000 32.14936 ? 857 HOH A O   1 
HETATM 8461 O  O   . HOH HA 4 .   ? 31.14787 43.23714  -45.32919 1.000 35.56029 ? 858 HOH A O   1 
HETATM 8462 O  O   . HOH HA 4 .   ? 41.59614 36.85045  -9.99768  1.000 27.24108 ? 859 HOH A O   1 
HETATM 8463 O  O   . HOH HA 4 .   ? 25.34244 -7.11298  -35.90057 1.000 30.26617 ? 860 HOH A O   1 
HETATM 8464 O  O   . HOH HA 4 .   ? 39.17344 16.46900  -31.47950 1.000 22.57596 ? 861 HOH A O   1 
HETATM 8465 O  O   . HOH HA 4 .   ? 29.98341 25.80876  -35.86793 1.000 13.80926 ? 862 HOH A O   1 
HETATM 8466 O  O   . HOH HA 4 .   ? -4.50614 25.27460  -16.40328 1.000 31.94072 ? 863 HOH A O   1 
HETATM 8467 O  O   . HOH HA 4 .   ? 10.50340 31.51151  -32.35295 1.000 21.96141 ? 864 HOH A O   1 
HETATM 8468 O  O   . HOH HA 4 .   ? 42.87010 23.88192  -33.20614 1.000 25.21477 ? 865 HOH A O   1 
HETATM 8469 O  O   . HOH HA 4 .   ? 27.90307 17.83147  -34.39604 1.000 17.55678 ? 866 HOH A O   1 
HETATM 8470 O  O   . HOH HA 4 .   ? 3.97236  41.80795  -13.59720 1.000 29.41491 ? 867 HOH A O   1 
HETATM 8471 O  O   . HOH HA 4 .   ? 17.27906 5.55202   -24.67920 1.000 22.51293 ? 868 HOH A O   1 
HETATM 8472 O  O   . HOH HA 4 .   ? 12.03683 17.26269  -28.16351 1.000 22.15019 ? 869 HOH A O   1 
HETATM 8473 O  O   . HOH HA 4 .   ? 16.10992 2.22534   -41.53403 1.000 35.52681 ? 870 HOH A O   1 
HETATM 8474 O  O   . HOH HA 4 .   ? 41.78742 17.01953  -31.57876 1.000 30.32574 ? 871 HOH A O   1 
HETATM 8475 O  O   . HOH HA 4 .   ? 16.96678 9.31995   -7.29891  1.000 29.63005 ? 872 HOH A O   1 
HETATM 8476 O  O   . HOH HA 4 .   ? 15.47435 15.30753  -4.29748  1.000 24.11911 ? 873 HOH A O   1 
HETATM 8477 O  O   . HOH HA 4 .   ? 38.61915 29.96194  -24.99520 1.000 18.47241 ? 874 HOH A O   1 
HETATM 8478 O  O   . HOH HA 4 .   ? 19.85431 51.72965  -23.75512 1.000 27.19911 ? 875 HOH A O   1 
HETATM 8479 O  O   . HOH HA 4 .   ? 25.27096 54.71774  -33.94300 1.000 29.17766 ? 876 HOH A O   1 
HETATM 8480 O  O   . HOH HA 4 .   ? 34.02836 17.98738  -40.76124 1.000 29.34508 ? 877 HOH A O   1 
HETATM 8481 O  O   . HOH HA 4 .   ? 16.01209 18.94000  5.40939   1.000 36.74519 ? 878 HOH A O   1 
HETATM 8482 O  O   . HOH HA 4 .   ? 34.35052 31.95909  -25.00701 1.000 20.78878 ? 879 HOH A O   1 
HETATM 8483 O  O   . HOH HA 4 .   ? 27.49582 19.15056  -4.80852  1.000 20.95943 ? 880 HOH A O   1 
HETATM 8484 O  O   . HOH HA 4 .   ? 10.27620 33.88228  -32.88755 1.000 22.43149 ? 881 HOH A O   1 
HETATM 8485 O  O   . HOH HA 4 .   ? 41.94080 39.99279  -38.72840 1.000 19.08055 ? 882 HOH A O   1 
HETATM 8486 O  O   . HOH HA 4 .   ? 13.77571 52.05216  -20.56957 1.000 40.79146 ? 883 HOH A O   1 
HETATM 8487 O  O   . HOH HA 4 .   ? 46.39178 50.76896  -23.56355 1.000 30.62739 ? 884 HOH A O   1 
HETATM 8488 O  O   . HOH HA 4 .   ? 21.66401 49.10391  -21.16538 1.000 16.84759 ? 885 HOH A O   1 
HETATM 8489 O  O   . HOH HA 4 .   ? 6.64181  40.65884  -13.83637 1.000 25.47219 ? 886 HOH A O   1 
HETATM 8490 O  O   . HOH HA 4 .   ? 34.35725 45.06870  -11.00655 1.000 31.03732 ? 887 HOH A O   1 
HETATM 8491 O  O   . HOH HA 4 .   ? 10.34853 28.95366  -42.20688 1.000 15.13346 ? 888 HOH A O   1 
HETATM 8492 O  O   . HOH HA 4 .   ? 35.84516 58.62618  -40.85864 1.000 38.52506 ? 889 HOH A O   1 
HETATM 8493 O  O   . HOH HA 4 .   ? 28.12360 15.53496  -2.41087  1.000 26.68063 ? 890 HOH A O   1 
HETATM 8494 O  O   . HOH HA 4 .   ? 46.18421 22.52245  -15.89935 1.000 31.66117 ? 891 HOH A O   1 
HETATM 8495 O  O   . HOH HA 4 .   ? 33.15999 48.13684  -48.44592 1.000 31.13759 ? 892 HOH A O   1 
HETATM 8496 O  O   . HOH HA 4 .   ? 18.20257 4.31653   -41.10211 1.000 21.97102 ? 893 HOH A O   1 
HETATM 8497 O  O   . HOH HA 4 .   ? 13.13063 44.75841  -7.80956  1.000 29.13072 ? 894 HOH A O   1 
HETATM 8498 O  O   . HOH HA 4 .   ? 25.91835 -3.94137  -32.11122 1.000 20.12856 ? 895 HOH A O   1 
HETATM 8499 O  O   . HOH HA 4 .   ? 6.05264  26.04219  -6.11003  1.000 28.12059 ? 896 HOH A O   1 
HETATM 8500 O  O   . HOH HA 4 .   ? 34.47999 2.63801   -29.87744 1.000 22.14001 ? 897 HOH A O   1 
HETATM 8501 O  O   . HOH HA 4 .   ? 1.76036  29.34792  -14.67877 1.000 25.60937 ? 898 HOH A O   1 
HETATM 8502 O  O   . HOH HA 4 .   ? 8.70996  13.74906  -4.19506  1.000 41.96988 ? 899 HOH A O   1 
HETATM 8503 O  O   . HOH HA 4 .   ? 17.02175 47.63822  -16.70616 1.000 32.03878 ? 900 HOH A O   1 
HETATM 8504 O  O   . HOH HA 4 .   ? 45.385   -7.225    2.337     1.000 30.63123 ? 901 HOH A O   1 
HETATM 8505 O  O   . HOH HA 4 .   ? 32.80205 45.52727  -14.15998 1.000 18.01634 ? 902 HOH A O   1 
HETATM 8506 O  O   . HOH HA 4 .   ? 15.62194 45.29221  -8.64445  1.000 20.97264 ? 903 HOH A O   1 
HETATM 8507 O  O   . HOH HA 4 .   ? 12.89453 9.61409   -29.34141 1.000 29.97772 ? 904 HOH A O   1 
HETATM 8508 O  O   . HOH HA 4 .   ? 6.50032  13.41916  -5.30905  1.000 49.31207 ? 905 HOH A O   1 
HETATM 8509 O  O   . HOH HA 4 .   ? 25.22994 49.74445  -43.10464 1.000 25.89397 ? 906 HOH A O   1 
HETATM 8510 O  O   . HOH HA 4 .   ? 45.62331 49.35007  -35.94691 1.000 35.87334 ? 907 HOH A O   1 
HETATM 8511 O  O   . HOH HA 4 .   ? 32.65822 44.71303  -44.10096 1.000 32.34650 ? 908 HOH A O   1 
HETATM 8512 O  O   . HOH HA 4 .   ? 47.220   55.487    -30.141   1.000 37.61990 ? 909 HOH A O   1 
HETATM 8513 O  O   . HOH HA 4 .   ? 14.64636 55.35465  -27.95550 1.000 31.95590 ? 910 HOH A O   1 
HETATM 8514 O  O   . HOH HA 4 .   ? 22.22535 1.65467   -18.30881 1.000 23.76094 ? 911 HOH A O   1 
HETATM 8515 O  O   . HOH HA 4 .   ? 33.925   24.149    3.642     1.000 25.29742 ? 912 HOH A O   1 
HETATM 8516 O  O   . HOH HA 4 .   ? 1.70807  14.13793  -7.82431  1.000 26.92960 ? 913 HOH A O   1 
HETATM 8517 O  O   . HOH HA 4 .   ? 17.18828 4.18394   -27.15077 1.000 31.62782 ? 914 HOH A O   1 
HETATM 8518 O  O   . HOH HA 4 .   ? 47.66399 31.83267  -13.20491 1.000 21.58731 ? 915 HOH A O   1 
HETATM 8519 O  O   . HOH HA 4 .   ? 5.40983  38.01173  -27.74455 1.000 39.59113 ? 916 HOH A O   1 
HETATM 8520 O  O   . HOH HA 4 .   ? 45.24024 -3.01670  -6.27014  1.000 54.39589 ? 917 HOH A O   1 
HETATM 8521 O  O   . HOH HA 4 .   ? 10.92208 29.03778  -34.16921 1.000 24.62200 ? 918 HOH A O   1 
HETATM 8522 O  O   . HOH HA 4 .   ? 44.18170 41.87311  -14.86578 1.000 38.05119 ? 919 HOH A O   1 
HETATM 8523 O  O   . HOH HA 4 .   ? 45.15859 34.45774  -5.77105  1.000 21.12197 ? 920 HOH A O   1 
HETATM 8524 O  O   . HOH HA 4 .   ? 42.64400 15.45675  -16.98401 1.000 34.69191 ? 921 HOH A O   1 
HETATM 8525 O  O   . HOH HA 4 .   ? 26.27808 39.25940  -1.05280  1.000 29.04567 ? 922 HOH A O   1 
HETATM 8526 O  O   . HOH HA 4 .   ? 38.92877 27.25026  -1.14650  1.000 39.60382 ? 923 HOH A O   1 
HETATM 8527 O  O   . HOH HA 4 .   ? 25.64041 7.84485   -45.55264 1.000 12.81549 ? 924 HOH A O   1 
HETATM 8528 O  O   . HOH HA 4 .   ? 39.82508 12.85274  -5.32692  1.000 15.86024 ? 925 HOH A O   1 
HETATM 8529 O  O   . HOH HA 4 .   ? 31.25523 32.67084  -22.41067 1.000 23.79642 ? 926 HOH A O   1 
HETATM 8530 O  O   . HOH HA 4 .   ? 32.727   0.858     -8.414    1.000 29.70131 ? 927 HOH A O   1 
HETATM 8531 O  O   . HOH HA 4 .   ? 51.422   40.118    -24.333   1.000 31.17959 ? 928 HOH A O   1 
HETATM 8532 O  O   . HOH HA 4 .   ? 17.73509 22.49608  -34.66304 1.000 17.81931 ? 929 HOH A O   1 
HETATM 8533 O  O   . HOH HA 4 .   ? 48.25949 5.76014   -21.04457 1.000 52.74849 ? 930 HOH A O   1 
HETATM 8534 O  O   . HOH HA 4 .   ? 27.05879 48.74808  -45.70811 1.000 25.26055 ? 931 HOH A O   1 
HETATM 8535 O  O   . HOH HA 4 .   ? 29.59178 28.07946  7.94984   1.000 31.41302 ? 932 HOH A O   1 
HETATM 8536 O  O   . HOH HA 4 .   ? 48.36665 34.33485  -12.62270 1.000 38.86149 ? 933 HOH A O   1 
HETATM 8537 O  O   . HOH HA 4 .   ? 20.50793 45.36298  -16.94085 1.000 24.89181 ? 934 HOH A O   1 
HETATM 8538 O  O   . HOH HA 4 .   ? 42.570   38.681    4.075     1.000 40.92143 ? 935 HOH A O   1 
HETATM 8539 O  O   . HOH HA 4 .   ? 27.60119 14.93283  -4.62845  1.000 26.52537 ? 936 HOH A O   1 
HETATM 8540 O  O   . HOH HA 4 .   ? 49.34654 39.02309  -34.71426 1.000 37.39294 ? 937 HOH A O   1 
HETATM 8541 O  O   . HOH HA 4 .   ? 35.572   19.666    4.289     1.000 34.22145 ? 938 HOH A O   1 
HETATM 8542 O  O   . HOH HA 4 .   ? -0.45397 37.57039  -22.51218 1.000 7.88048  ? 939 HOH A O   1 
HETATM 8543 O  O   . HOH HA 4 .   ? 4.22303  31.57742  -16.00752 1.000 28.35772 ? 940 HOH A O   1 
HETATM 8544 O  O   . HOH HA 4 .   ? 5.277    39.981    -5.013    1.000 35.43987 ? 941 HOH A O   1 
HETATM 8545 O  O   . HOH HA 4 .   ? 42.901   -6.984    1.808     1.000 31.65974 ? 942 HOH A O   1 
HETATM 8546 O  O   . HOH HA 4 .   ? 8.95862  23.57567  -38.46223 1.000 24.56191 ? 943 HOH A O   1 
HETATM 8547 O  O   . HOH HA 4 .   ? 31.84008 49.15709  -26.11255 1.000 20.82299 ? 944 HOH A O   1 
HETATM 8548 O  O   . HOH HA 4 .   ? 1.17479  16.39580  -7.37062  1.000 35.31907 ? 945 HOH A O   1 
HETATM 8549 O  O   . HOH HA 4 .   ? 20.24314 24.70342  9.11997   1.000 35.19212 ? 946 HOH A O   1 
HETATM 8550 O  O   . HOH HA 4 .   ? 9.60532  40.95931  -39.96571 1.000 18.92438 ? 947 HOH A O   1 
HETATM 8551 O  O   . HOH HA 4 .   ? 40.51456 40.11919  -16.84245 1.000 30.59355 ? 948 HOH A O   1 
HETATM 8552 O  O   . HOH HA 4 .   ? 40.00777 14.80548  -34.26396 1.000 37.91093 ? 949 HOH A O   1 
HETATM 8553 O  O   . HOH HA 4 .   ? 12.05487 44.24100  -5.89390  1.000 32.10843 ? 950 HOH A O   1 
HETATM 8554 O  O   . HOH HA 4 .   ? 42.23614 15.40152  -23.71613 1.000 31.12955 ? 951 HOH A O   1 
HETATM 8555 O  O   . HOH HA 4 .   ? 25.65675 39.11750  1.57866   1.000 33.76322 ? 952 HOH A O   1 
HETATM 8556 O  O   . HOH HA 4 .   ? 43.40541 38.50794  -22.47066 1.000 25.49471 ? 953 HOH A O   1 
HETATM 8557 O  O   . HOH HA 4 .   ? 24.39178 52.30796  -42.37952 1.000 38.51510 ? 954 HOH A O   1 
HETATM 8558 O  O   . HOH HA 4 .   ? 19.33765 46.15682  -15.02211 1.000 27.47593 ? 955 HOH A O   1 
HETATM 8559 O  O   . HOH HA 4 .   ? 14.38389 54.67647  -31.72056 1.000 35.21061 ? 956 HOH A O   1 
HETATM 8560 O  O   . HOH HA 4 .   ? 8.37781  30.18624  -31.14071 1.000 30.63512 ? 957 HOH A O   1 
HETATM 8561 O  O   . HOH HA 4 .   ? 50.53796 41.04778  -34.65961 1.000 28.78507 ? 958 HOH A O   1 
HETATM 8562 O  O   . HOH HA 4 .   ? 31.21269 4.69239   -34.57431 1.000 24.87893 ? 959 HOH A O   1 
HETATM 8563 O  O   . HOH HA 4 .   ? 21.47651 45.16890  -14.29842 1.000 29.64104 ? 960 HOH A O   1 
HETATM 8564 O  O   . HOH HA 4 .   ? 20.72113 12.27869  -41.33468 1.000 19.63818 ? 961 HOH A O   1 
HETATM 8565 O  O   . HOH HA 4 .   ? 23.72709 43.12622  -16.95906 1.000 35.32072 ? 962 HOH A O   1 
HETATM 8566 O  O   . HOH HA 4 .   ? 10.10482 26.51965  -42.47964 1.000 19.92618 ? 963 HOH A O   1 
HETATM 8567 O  O   . HOH HA 4 .   ? 5.51604  33.79851  -3.64454  1.000 21.34456 ? 964 HOH A O   1 
HETATM 8568 O  O   . HOH HA 4 .   ? 30.29357 26.81521  9.69815   1.000 28.25105 ? 965 HOH A O   1 
HETATM 8569 O  O   . HOH HA 4 .   ? 21.88712 52.50445  -21.45570 1.000 37.81010 ? 966 HOH A O   1 
HETATM 8570 O  O   . HOH HA 4 .   ? 28.13862 8.35689   -3.13896  1.000 32.98791 ? 967 HOH A O   1 
HETATM 8571 O  O   . HOH HA 4 .   ? 21.31336 8.03229   -42.95966 1.000 16.17317 ? 968 HOH A O   1 
HETATM 8572 O  O   . HOH HA 4 .   ? 25.11827 14.45870  -39.48094 1.000 32.10317 ? 969 HOH A O   1 
HETATM 8573 O  O   . HOH HA 4 .   ? 22.02641 15.11369  -39.29657 1.000 27.50149 ? 970 HOH A O   1 
HETATM 8574 O  O   . HOH HA 4 .   ? 28.85646 42.72572  -4.62033  1.000 24.88755 ? 971 HOH A O   1 
HETATM 8575 O  O   . HOH HA 4 .   ? 43.88772 19.09192  -21.25581 1.000 26.57282 ? 972 HOH A O   1 
HETATM 8576 O  O   . HOH HA 4 .   ? 7.01003  27.09058  -39.30568 1.000 34.61880 ? 973 HOH A O   1 
HETATM 8577 O  O   . HOH HA 4 .   ? 17.41709 42.18350  -5.34345  1.000 19.47424 ? 974 HOH A O   1 
HETATM 8578 O  O   . HOH HA 4 .   ? 45.24344 21.16391  -38.32873 1.000 29.24380 ? 975 HOH A O   1 
HETATM 8579 O  O   . HOH HA 4 .   ? 22.51815 10.50056  -41.68221 1.000 16.50392 ? 976 HOH A O   1 
HETATM 8580 O  O   . HOH HA 4 .   ? 42.715   -8.369    -7.393    1.000 23.30078 ? 977 HOH A O   1 
HETATM 8581 O  O   . HOH HA 4 .   ? 26.30820 20.99071  -36.20858 1.000 22.40750 ? 978 HOH A O   1 
HETATM 8582 O  O   . HOH HA 4 .   ? 35.63624 45.34810  -13.82754 1.000 22.47668 ? 979 HOH A O   1 
HETATM 8583 O  O   . HOH HA 4 .   ? -6.40924 25.24824  -28.58147 1.000 31.33619 ? 980 HOH A O   1 
HETATM 8584 O  O   . HOH HA 4 .   ? 11.32728 13.13572  -38.44144 1.000 35.07985 ? 981 HOH A O   1 
HETATM 8585 O  O   . HOH HA 4 .   ? 22.26031 17.40046  -38.03784 1.000 25.75071 ? 982 HOH A O   1 
HETATM 8586 O  O   . HOH HA 4 .   ? 34.48750 59.01689  -42.65197 1.000 44.18044 ? 983 HOH A O   1 
HETATM 8587 O  O   . HOH HA 4 .   ? 26.41841 10.16179  -44.86004 1.000 16.71607 ? 984 HOH A O   1 
HETATM 8588 O  O   . HOH HA 4 .   ? 25.25181 17.31325  -37.80080 1.000 37.87807 ? 985 HOH A O   1 
HETATM 8589 O  O   . HOH HA 4 .   ? 17.63891 7.68082   -41.25173 1.000 24.13344 ? 986 HOH A O   1 
HETATM 8590 O  O   . HOH HA 4 .   ? 49.79426 4.60987   -19.69708 1.000 49.85560 ? 987 HOH A O   1 
HETATM 8591 O  O   . HOH HA 4 .   ? 45.52452 13.08099  -31.14250 1.000 33.34894 ? 988 HOH A O   1 
HETATM 8592 O  O   . HOH IA 4 .   ? 50.61885 -15.68368 -61.65886 1.000 27.73585 ? 701 HOH B O   1 
HETATM 8593 O  O   . HOH IA 4 .   ? 27.66324 -3.73129  -87.62580 1.000 41.85230 ? 702 HOH B O   1 
HETATM 8594 O  O   . HOH IA 4 .   ? 22.35116 -6.91220  -63.94242 1.000 24.22436 ? 703 HOH B O   1 
HETATM 8595 O  O   . HOH IA 4 .   ? 26.16121 35.54379  -62.27645 1.000 36.38100 ? 704 HOH B O   1 
HETATM 8596 O  O   . HOH IA 4 .   ? 65.61262 10.14815  -56.09195 1.000 29.02951 ? 705 HOH B O   1 
HETATM 8597 O  O   . HOH IA 4 .   ? 16.51699 26.86758  -55.06140 1.000 17.02935 ? 706 HOH B O   1 
HETATM 8598 O  O   . HOH IA 4 .   ? 9.47690  -0.18643  -68.30515 1.000 38.98913 ? 707 HOH B O   1 
HETATM 8599 O  O   . HOH IA 4 .   ? 42.54972 -13.80358 -45.88935 1.000 38.56124 ? 708 HOH B O   1 
HETATM 8600 O  O   . HOH IA 4 .   ? 15.37358 5.29147   -51.10492 1.000 29.68857 ? 709 HOH B O   1 
HETATM 8601 O  O   . HOH IA 4 .   ? 19.87470 12.75320  -75.82773 1.000 18.08959 ? 710 HOH B O   1 
HETATM 8602 O  O   . HOH IA 4 .   ? 44.09682 11.19854  -63.17751 1.000 18.52557 ? 711 HOH B O   1 
HETATM 8603 O  O   . HOH IA 4 .   ? 36.32706 -10.90289 -67.91521 1.000 24.44791 ? 712 HOH B O   1 
HETATM 8604 O  O   . HOH IA 4 .   ? 32.28806 -12.23547 -67.40828 1.000 19.37112 ? 713 HOH B O   1 
HETATM 8605 O  O   . HOH IA 4 .   ? 13.82213 37.42454  -82.05031 1.000 34.85128 ? 714 HOH B O   1 
HETATM 8606 O  O   . HOH IA 4 .   ? 11.10118 3.17498   -67.08192 1.000 41.55180 ? 715 HOH B O   1 
HETATM 8607 O  O   . HOH IA 4 .   ? 27.05100 -11.09709 -82.07038 1.000 36.83817 ? 716 HOH B O   1 
HETATM 8608 O  O   . HOH IA 4 .   ? 33.96004 9.68136   -82.47551 1.000 20.40854 ? 717 HOH B O   1 
HETATM 8609 O  O   . HOH IA 4 .   ? 41.52879 -13.25020 -49.78863 1.000 35.01316 ? 718 HOH B O   1 
HETATM 8610 O  O   . HOH IA 4 .   ? 50.09875 28.23878  -64.09644 1.000 27.54038 ? 719 HOH B O   1 
HETATM 8611 O  O   . HOH IA 4 .   ? 32.48602 37.99844  -58.33219 1.000 41.74285 ? 720 HOH B O   1 
HETATM 8612 O  O   . HOH IA 4 .   ? 16.99413 11.23546  -63.93158 1.000 18.84531 ? 721 HOH B O   1 
HETATM 8613 O  O   . HOH IA 4 .   ? 52.32832 -16.71208 -50.76023 1.000 32.79625 ? 722 HOH B O   1 
HETATM 8614 O  O   . HOH IA 4 .   ? 21.10557 30.47146  -66.08801 1.000 11.60197 ? 723 HOH B O   1 
HETATM 8615 O  O   . HOH IA 4 .   ? 46.80263 -6.18075  -63.96844 1.000 19.82895 ? 724 HOH B O   1 
HETATM 8616 O  O   . HOH IA 4 .   ? 33.36161 -1.52559  -59.40861 1.000 26.22251 ? 725 HOH B O   1 
HETATM 8617 O  O   . HOH IA 4 .   ? 54.02723 5.57945   -66.43257 1.000 27.33448 ? 726 HOH B O   1 
HETATM 8618 O  O   . HOH IA 4 .   ? 56.67820 5.19798   -58.61980 1.000 20.62967 ? 727 HOH B O   1 
HETATM 8619 O  O   . HOH IA 4 .   ? 21.86458 -10.80170 -58.28816 1.000 35.74268 ? 728 HOH B O   1 
HETATM 8620 O  O   . HOH IA 4 .   ? 39.22660 -6.11359  -79.94670 1.000 19.23999 ? 729 HOH B O   1 
HETATM 8621 O  O   . HOH IA 4 .   ? 45.26070 28.24613  -60.20906 1.000 27.51638 ? 730 HOH B O   1 
HETATM 8622 O  O   . HOH IA 4 .   ? 22.96197 -6.00579  -66.99318 1.000 20.63012 ? 731 HOH B O   1 
HETATM 8623 O  O   . HOH IA 4 .   ? 47.00497 25.12369  -60.79954 1.000 28.28484 ? 732 HOH B O   1 
HETATM 8624 O  O   . HOH IA 4 .   ? 53.43803 23.43200  -67.64624 1.000 28.93726 ? 733 HOH B O   1 
HETATM 8625 O  O   . HOH IA 4 .   ? 25.93424 7.08717   -69.77223 1.000 13.79782 ? 734 HOH B O   1 
HETATM 8626 O  O   . HOH IA 4 .   ? 17.79381 18.78130  -67.91499 1.000 15.93858 ? 735 HOH B O   1 
HETATM 8627 O  O   . HOH IA 4 .   ? 49.02663 14.81847  -36.83197 1.000 44.74584 ? 736 HOH B O   1 
HETATM 8628 O  O   . HOH IA 4 .   ? 39.24938 24.38196  -72.72360 1.000 17.49538 ? 737 HOH B O   1 
HETATM 8629 O  O   . HOH IA 4 .   ? 20.56995 7.06446   -68.29874 1.000 26.27621 ? 738 HOH B O   1 
HETATM 8630 O  O   . HOH IA 4 .   ? 14.83152 -0.51138  -76.08344 1.000 48.00384 ? 739 HOH B O   1 
HETATM 8631 O  O   . HOH IA 4 .   ? 28.62144 12.64130  -71.87894 1.000 16.02245 ? 740 HOH B O   1 
HETATM 8632 O  O   . HOH IA 4 .   ? 55.63910 2.97553   -57.47319 1.000 14.64725 ? 741 HOH B O   1 
HETATM 8633 O  O   . HOH IA 4 .   ? 35.07833 16.13105  -71.58442 1.000 12.43913 ? 742 HOH B O   1 
HETATM 8634 O  O   . HOH IA 4 .   ? 54.41158 15.96842  -59.02024 1.000 16.09391 ? 743 HOH B O   1 
HETATM 8635 O  O   . HOH IA 4 .   ? 60.43676 18.42311  -57.47593 1.000 29.24317 ? 744 HOH B O   1 
HETATM 8636 O  O   . HOH IA 4 .   ? 39.39434 -14.01719 -50.42748 1.000 34.76232 ? 745 HOH B O   1 
HETATM 8637 O  O   . HOH IA 4 .   ? 37.97778 15.70263  -54.34337 1.000 9.31765  ? 746 HOH B O   1 
HETATM 8638 O  O   . HOH IA 4 .   ? 14.37979 25.01674  -59.16260 1.000 22.20665 ? 747 HOH B O   1 
HETATM 8639 O  O   . HOH IA 4 .   ? 19.31560 1.45923   -61.60169 1.000 23.24588 ? 748 HOH B O   1 
HETATM 8640 O  O   . HOH IA 4 .   ? 48.28328 17.83894  -62.20406 1.000 18.26890 ? 749 HOH B O   1 
HETATM 8641 O  O   . HOH IA 4 .   ? 36.28594 8.72829   -81.88110 1.000 19.60254 ? 750 HOH B O   1 
HETATM 8642 O  O   . HOH IA 4 .   ? 44.88517 23.67811  -60.17131 1.000 19.46533 ? 751 HOH B O   1 
HETATM 8643 O  O   . HOH IA 4 .   ? 13.10074 25.68091  -52.41256 1.000 19.16596 ? 752 HOH B O   1 
HETATM 8644 O  O   . HOH IA 4 .   ? 22.24031 -6.54655  -80.33097 1.000 46.73783 ? 753 HOH B O   1 
HETATM 8645 O  O   . HOH IA 4 .   ? 29.25709 15.16624  -48.67924 1.000 21.82063 ? 754 HOH B O   1 
HETATM 8646 O  O   . HOH IA 4 .   ? 17.26969 -0.45611  -60.76584 1.000 20.77508 ? 755 HOH B O   1 
HETATM 8647 O  O   . HOH IA 4 .   ? 22.70367 5.01672   -46.23512 1.000 18.73188 ? 756 HOH B O   1 
HETATM 8648 O  O   . HOH IA 4 .   ? 18.582   29.566    -67.224   1.000 11.17666 ? 757 HOH B O   1 
HETATM 8649 O  O   . HOH IA 4 .   ? 27.36907 16.91574  -76.45526 1.000 20.32731 ? 758 HOH B O   1 
HETATM 8650 O  O   . HOH IA 4 .   ? 30.78860 -5.39431  -90.98845 1.000 40.83219 ? 759 HOH B O   1 
HETATM 8651 O  O   . HOH IA 4 .   ? 39.802   14.770    -88.148   1.000 28.79002 ? 760 HOH B O   1 
HETATM 8652 O  O   . HOH IA 4 .   ? 23.17116 17.14432  -43.60015 1.000 15.32177 ? 761 HOH B O   1 
HETATM 8653 O  O   . HOH IA 4 .   ? 15.89973 15.41116  -73.90458 1.000 22.52479 ? 762 HOH B O   1 
HETATM 8654 O  O   . HOH IA 4 .   ? 35.83088 13.19634  -74.08782 1.000 10.97543 ? 763 HOH B O   1 
HETATM 8655 O  O   . HOH IA 4 .   ? 32.89038 17.91532  -69.17423 1.000 13.71760 ? 764 HOH B O   1 
HETATM 8656 O  O   . HOH IA 4 .   ? 48.22627 -11.24723 -46.85660 1.000 35.21450 ? 765 HOH B O   1 
HETATM 8657 O  O   . HOH IA 4 .   ? 10.79172 19.00791  -46.20046 1.000 19.61926 ? 766 HOH B O   1 
HETATM 8658 O  O   . HOH IA 4 .   ? 46.73257 20.09685  -59.82006 1.000 12.81963 ? 767 HOH B O   1 
HETATM 8659 O  O   . HOH IA 4 .   ? 40.78893 19.56139  -70.48851 1.000 16.47674 ? 768 HOH B O   1 
HETATM 8660 O  O   . HOH IA 4 .   ? 47.10770 -5.74504  -71.30030 1.000 12.87823 ? 769 HOH B O   1 
HETATM 8661 O  O   . HOH IA 4 .   ? 30.77781 2.61029   -49.01641 1.000 12.74844 ? 770 HOH B O   1 
HETATM 8662 O  O   . HOH IA 4 .   ? 39.00904 27.60790  -75.20503 1.000 31.31058 ? 771 HOH B O   1 
HETATM 8663 O  O   . HOH IA 4 .   ? 35.79885 -2.11029  -60.98530 1.000 21.23377 ? 772 HOH B O   1 
HETATM 8664 O  O   . HOH IA 4 .   ? 50.66475 27.20005  -66.95499 1.000 30.11148 ? 773 HOH B O   1 
HETATM 8665 O  O   . HOH IA 4 .   ? 16.92132 -3.04363  -60.66227 1.000 23.58052 ? 774 HOH B O   1 
HETATM 8666 O  O   . HOH IA 4 .   ? 38.11194 2.11916   -86.16955 1.000 28.99045 ? 775 HOH B O   1 
HETATM 8667 O  O   . HOH IA 4 .   ? 30.60647 12.51005  -82.31631 1.000 25.07993 ? 776 HOH B O   1 
HETATM 8668 O  O   . HOH IA 4 .   ? 31.76420 15.08298  -52.12387 1.000 8.70679  ? 777 HOH B O   1 
HETATM 8669 O  O   . HOH IA 4 .   ? 41.62723 0.36230   -70.53514 1.000 14.77194 ? 778 HOH B O   1 
HETATM 8670 O  O   . HOH IA 4 .   ? 50.48540 11.72846  -73.03312 1.000 20.04622 ? 779 HOH B O   1 
HETATM 8671 O  O   . HOH IA 4 .   ? 22.28158 23.08880  -48.08387 1.000 14.52962 ? 780 HOH B O   1 
HETATM 8672 O  O   . HOH IA 4 .   ? 15.63359 17.64166  -64.58346 1.000 23.72421 ? 781 HOH B O   1 
HETATM 8673 O  O   . HOH IA 4 .   ? 27.49998 15.54932  -80.79213 1.000 28.03172 ? 782 HOH B O   1 
HETATM 8674 O  O   . HOH IA 4 .   ? 40.56508 22.95402  -56.04607 1.000 9.53275  ? 783 HOH B O   1 
HETATM 8675 O  O   . HOH IA 4 .   ? 28.10612 15.39354  -72.89995 1.000 16.07240 ? 784 HOH B O   1 
HETATM 8676 O  O   . HOH IA 4 .   ? 21.74622 -2.45170  -70.46871 1.000 15.16984 ? 785 HOH B O   1 
HETATM 8677 O  O   . HOH IA 4 .   ? 33.74014 0.65577   -49.29510 1.000 16.96227 ? 786 HOH B O   1 
HETATM 8678 O  O   . HOH IA 4 .   ? 33.93452 22.99800  -52.84714 1.000 12.51020 ? 787 HOH B O   1 
HETATM 8679 O  O   . HOH IA 4 .   ? 45.89718 5.55185   -66.92337 1.000 15.97613 ? 788 HOH B O   1 
HETATM 8680 O  O   . HOH IA 4 .   ? 19.16562 26.87888  -55.00228 1.000 14.94730 ? 789 HOH B O   1 
HETATM 8681 O  O   . HOH IA 4 .   ? 32.86063 18.51472  -65.17935 1.000 9.96728  ? 790 HOH B O   1 
HETATM 8682 O  O   . HOH IA 4 .   ? 50.75197 -3.19625  -42.16447 1.000 21.10055 ? 791 HOH B O   1 
HETATM 8683 O  O   . HOH IA 4 .   ? 43.27203 -12.23188 -63.76521 1.000 20.01939 ? 792 HOH B O   1 
HETATM 8684 O  O   . HOH IA 4 .   ? 65.68825 15.24328  -46.80031 1.000 32.20724 ? 793 HOH B O   1 
HETATM 8685 O  O   . HOH IA 4 .   ? 36.17159 3.14908   -84.47808 1.000 25.46480 ? 794 HOH B O   1 
HETATM 8686 O  O   . HOH IA 4 .   ? 17.12933 14.56265  -42.56254 1.000 20.51050 ? 795 HOH B O   1 
HETATM 8687 O  O   . HOH IA 4 .   ? 35.22841 3.90118   -74.48318 1.000 12.35732 ? 796 HOH B O   1 
HETATM 8688 O  O   . HOH IA 4 .   ? 34.14340 24.92805  -67.13706 1.000 20.71624 ? 797 HOH B O   1 
HETATM 8689 O  O   . HOH IA 4 .   ? 48.62261 -9.06771  -55.06504 1.000 17.49561 ? 798 HOH B O   1 
HETATM 8690 O  O   . HOH IA 4 .   ? 4.31821  -5.24773  -67.29957 1.000 26.35927 ? 799 HOH B O   1 
HETATM 8691 O  O   . HOH IA 4 .   ? 34.52041 8.91550   -78.13319 1.000 12.48085 ? 800 HOH B O   1 
HETATM 8692 O  O   . HOH IA 4 .   ? 51.88278 -0.59173  -66.67806 1.000 12.62977 ? 801 HOH B O   1 
HETATM 8693 O  O   . HOH IA 4 .   ? 31.42145 5.28324   -61.58646 1.000 17.73753 ? 802 HOH B O   1 
HETATM 8694 O  O   . HOH IA 4 .   ? 45.43975 7.60551   -42.09322 1.000 20.01528 ? 803 HOH B O   1 
HETATM 8695 O  O   . HOH IA 4 .   ? 13.91492 12.79720  -58.30584 1.000 23.82909 ? 804 HOH B O   1 
HETATM 8696 O  O   . HOH IA 4 .   ? 42.37578 24.52043  -60.46851 1.000 22.18743 ? 805 HOH B O   1 
HETATM 8697 O  O   . HOH IA 4 .   ? 20.30158 -5.28792  -80.53748 1.000 26.00876 ? 806 HOH B O   1 
HETATM 8698 O  O   . HOH IA 4 .   ? 59.81460 -4.96968  -48.41874 1.000 25.68741 ? 807 HOH B O   1 
HETATM 8699 O  O   . HOH IA 4 .   ? 32.50147 -10.06577 -46.93452 1.000 28.68405 ? 808 HOH B O   1 
HETATM 8700 O  O   . HOH IA 4 .   ? 61.59840 9.81758   -61.16634 1.000 33.92564 ? 809 HOH B O   1 
HETATM 8701 O  O   . HOH IA 4 .   ? 52.34444 11.89780  -43.89347 1.000 19.89739 ? 810 HOH B O   1 
HETATM 8702 O  O   . HOH IA 4 .   ? 65.32388 1.88999   -58.76493 1.000 41.77594 ? 811 HOH B O   1 
HETATM 8703 O  O   . HOH IA 4 .   ? 6.76632  23.02680  -53.71708 1.000 33.82835 ? 812 HOH B O   1 
HETATM 8704 O  O   . HOH IA 4 .   ? 33.13410 16.55012  -67.08088 1.000 11.87119 ? 813 HOH B O   1 
HETATM 8705 O  O   . HOH IA 4 .   ? 52.11098 27.90861  -73.10119 1.000 29.62461 ? 814 HOH B O   1 
HETATM 8706 O  O   . HOH IA 4 .   ? 24.58713 -5.01865  -45.93358 1.000 27.34669 ? 815 HOH B O   1 
HETATM 8707 O  O   . HOH IA 4 .   ? 23.39637 5.65368   -69.69790 1.000 20.24327 ? 816 HOH B O   1 
HETATM 8708 O  O   . HOH IA 4 .   ? 11.940   18.066    -64.725   1.000 26.10048 ? 817 HOH B O   1 
HETATM 8709 O  O   . HOH IA 4 .   ? 0.28264  20.98681  -48.56659 1.000 31.54338 ? 818 HOH B O   1 
HETATM 8710 O  O   . HOH IA 4 .   ? 23.15982 -3.84812  -63.69108 1.000 17.36964 ? 819 HOH B O   1 
HETATM 8711 O  O   . HOH IA 4 .   ? 62.75852 -3.00542  -51.52919 1.000 23.35271 ? 820 HOH B O   1 
HETATM 8712 O  O   . HOH IA 4 .   ? 39.86809 20.48853  -72.94485 1.000 23.42993 ? 821 HOH B O   1 
HETATM 8713 O  O   . HOH IA 4 .   ? 11.90438 -1.13332  -68.62317 1.000 25.53964 ? 822 HOH B O   1 
HETATM 8714 O  O   . HOH IA 4 .   ? 30.09848 14.58306  -80.84914 1.000 22.34493 ? 823 HOH B O   1 
HETATM 8715 O  O   . HOH IA 4 .   ? 26.64076 -13.31304 -64.57435 1.000 28.26289 ? 824 HOH B O   1 
HETATM 8716 O  O   . HOH IA 4 .   ? 36.18036 -0.88028  -40.14409 1.000 28.35791 ? 825 HOH B O   1 
HETATM 8717 O  O   . HOH IA 4 .   ? 38.41513 15.98955  -51.56817 1.000 18.77960 ? 826 HOH B O   1 
HETATM 8718 O  O   . HOH IA 4 .   ? 42.07076 6.13205   -89.19407 1.000 20.76856 ? 827 HOH B O   1 
HETATM 8719 O  O   . HOH IA 4 .   ? 61.20848 13.59534  -46.25801 1.000 23.02451 ? 828 HOH B O   1 
HETATM 8720 O  O   . HOH IA 4 .   ? 48.95002 -10.42515 -67.62399 1.000 20.05663 ? 829 HOH B O   1 
HETATM 8721 O  O   . HOH IA 4 .   ? 27.85618 -16.81756 -62.84301 1.000 25.37613 ? 830 HOH B O   1 
HETATM 8722 O  O   . HOH IA 4 .   ? 10.50107 12.93499  -41.52135 1.000 29.27240 ? 831 HOH B O   1 
HETATM 8723 O  O   . HOH IA 4 .   ? 23.99589 19.70981  -39.90515 1.000 18.65133 ? 832 HOH B O   1 
HETATM 8724 O  O   . HOH IA 4 .   ? 47.00998 28.80188  -63.40951 1.000 33.06662 ? 833 HOH B O   1 
HETATM 8725 O  O   . HOH IA 4 .   ? 27.54686 3.65532   -52.63897 1.000 26.79459 ? 834 HOH B O   1 
HETATM 8726 O  O   . HOH IA 4 .   ? 43.89923 16.61487  -58.71598 1.000 19.36718 ? 835 HOH B O   1 
HETATM 8727 O  O   . HOH IA 4 .   ? 49.01529 -11.04076 -61.85358 1.000 30.01566 ? 836 HOH B O   1 
HETATM 8728 O  O   . HOH IA 4 .   ? 32.13147 27.69864  -60.48915 1.000 19.05980 ? 837 HOH B O   1 
HETATM 8729 O  O   . HOH IA 4 .   ? 25.49200 6.12210   -48.06750 1.000 23.98493 ? 838 HOH B O   1 
HETATM 8730 O  O   . HOH IA 4 .   ? 40.34086 -9.69690  -79.40641 1.000 29.82556 ? 839 HOH B O   1 
HETATM 8731 O  O   . HOH IA 4 .   ? 60.82895 -8.12781  -52.66212 1.000 46.30912 ? 840 HOH B O   1 
HETATM 8732 O  O   . HOH IA 4 .   ? 30.29353 14.35142  -77.70799 1.000 17.79391 ? 841 HOH B O   1 
HETATM 8733 O  O   . HOH IA 4 .   ? 30.70483 -4.99073  -48.40091 1.000 26.43202 ? 842 HOH B O   1 
HETATM 8734 O  O   . HOH IA 4 .   ? 58.56989 21.14606  -47.44182 1.000 20.00915 ? 843 HOH B O   1 
HETATM 8735 O  O   . HOH IA 4 .   ? 11.37873 21.64517  -39.00291 1.000 20.61751 ? 844 HOH B O   1 
HETATM 8736 O  O   . HOH IA 4 .   ? 54.18572 11.44714  -74.10853 1.000 35.31817 ? 845 HOH B O   1 
HETATM 8737 O  O   . HOH IA 4 .   ? 32.30485 -18.85805 -65.69703 1.000 31.60518 ? 846 HOH B O   1 
HETATM 8738 O  O   . HOH IA 4 .   ? 52.62926 17.46320  -72.68639 1.000 17.86464 ? 847 HOH B O   1 
HETATM 8739 O  O   . HOH IA 4 .   ? 19.49966 -16.87157 -66.57582 1.000 30.47704 ? 848 HOH B O   1 
HETATM 8740 O  O   . HOH IA 4 .   ? 29.17164 -2.72713  -85.64520 1.000 34.04598 ? 849 HOH B O   1 
HETATM 8741 O  O   . HOH IA 4 .   ? 48.50598 7.75649   -79.22694 1.000 22.18945 ? 850 HOH B O   1 
HETATM 8742 O  O   . HOH IA 4 .   ? 19.75940 28.62623  -52.70601 1.000 19.88481 ? 851 HOH B O   1 
HETATM 8743 O  O   . HOH IA 4 .   ? 9.37801  24.45786  -50.46282 1.000 19.85386 ? 852 HOH B O   1 
HETATM 8744 O  O   . HOH IA 4 .   ? 17.65040 16.57051  -38.80135 1.000 22.17373 ? 853 HOH B O   1 
HETATM 8745 O  O   . HOH IA 4 .   ? 53.15965 -6.00605  -61.29657 1.000 18.21694 ? 854 HOH B O   1 
HETATM 8746 O  O   . HOH IA 4 .   ? 41.11972 -19.98365 -59.22612 1.000 37.25085 ? 855 HOH B O   1 
HETATM 8747 O  O   . HOH IA 4 .   ? 60.98496 23.63350  -49.14616 1.000 36.51142 ? 856 HOH B O   1 
HETATM 8748 O  O   . HOH IA 4 .   ? 57.72224 25.21203  -50.96241 1.000 30.91579 ? 857 HOH B O   1 
HETATM 8749 O  O   . HOH IA 4 .   ? 25.30946 34.32716  -72.81712 1.000 20.18330 ? 858 HOH B O   1 
HETATM 8750 O  O   . HOH IA 4 .   ? 45.37794 18.38906  -57.94852 1.000 17.19522 ? 859 HOH B O   1 
HETATM 8751 O  O   . HOH IA 4 .   ? 56.91103 24.58466  -53.23172 1.000 34.49022 ? 860 HOH B O   1 
HETATM 8752 O  O   . HOH IA 4 .   ? 18.26118 25.30324  -50.45617 1.000 6.94692  ? 861 HOH B O   1 
HETATM 8753 O  O   . HOH IA 4 .   ? 57.09970 19.50940  -86.00093 1.000 37.90464 ? 862 HOH B O   1 
HETATM 8754 O  O   . HOH IA 4 .   ? 22.36468 5.74184   -53.35623 1.000 16.66847 ? 863 HOH B O   1 
HETATM 8755 O  O   . HOH IA 4 .   ? 34.73743 25.72712  -64.09279 1.000 32.04187 ? 864 HOH B O   1 
HETATM 8756 O  O   . HOH IA 4 .   ? 45.29195 -5.61687  -42.54569 1.000 31.67958 ? 865 HOH B O   1 
HETATM 8757 O  O   . HOH IA 4 .   ? 19.51364 7.13407   -44.16764 1.000 24.49752 ? 866 HOH B O   1 
HETATM 8758 O  O   . HOH IA 4 .   ? 24.45934 4.47859   -88.08900 1.000 28.82483 ? 867 HOH B O   1 
HETATM 8759 O  O   . HOH IA 4 .   ? 12.64747 25.46474  -43.68355 1.000 16.58477 ? 868 HOH B O   1 
HETATM 8760 O  O   . HOH IA 4 .   ? 17.12706 -7.84843  -71.23519 1.000 22.93116 ? 869 HOH B O   1 
HETATM 8761 O  O   . HOH IA 4 .   ? 54.47587 5.10089   -37.36932 1.000 41.43392 ? 870 HOH B O   1 
HETATM 8762 O  O   . HOH IA 4 .   ? 54.81275 6.40587   -60.79818 1.000 18.10565 ? 871 HOH B O   1 
HETATM 8763 O  O   . HOH IA 4 .   ? 18.09273 13.41163  -73.62734 1.000 17.16092 ? 872 HOH B O   1 
HETATM 8764 O  O   . HOH IA 4 .   ? 34.70164 -8.29589  -49.57989 1.000 20.95913 ? 873 HOH B O   1 
HETATM 8765 O  O   . HOH IA 4 .   ? 22.17571 -1.12906  -84.08069 1.000 31.94933 ? 874 HOH B O   1 
HETATM 8766 O  O   . HOH IA 4 .   ? 32.01736 -15.75866 -66.97863 1.000 24.82066 ? 875 HOH B O   1 
HETATM 8767 O  O   . HOH IA 4 .   ? 16.40812 9.66478   -75.64522 1.000 18.52755 ? 876 HOH B O   1 
HETATM 8768 O  O   . HOH IA 4 .   ? 12.97966 13.27230  -41.87106 1.000 20.23968 ? 877 HOH B O   1 
HETATM 8769 O  O   . HOH IA 4 .   ? 45.47096 -11.01267 -74.49847 1.000 27.28039 ? 878 HOH B O   1 
HETATM 8770 O  O   . HOH IA 4 .   ? 49.82722 -8.86752  -65.89378 1.000 19.11722 ? 879 HOH B O   1 
HETATM 8771 O  O   . HOH IA 4 .   ? 60.13086 15.45613  -45.20987 1.000 33.98265 ? 880 HOH B O   1 
HETATM 8772 O  O   . HOH IA 4 .   ? 20.74948 1.56071   -54.62103 1.000 25.47099 ? 881 HOH B O   1 
HETATM 8773 O  O   . HOH IA 4 .   ? 39.28273 12.87047  -91.26502 1.000 28.87074 ? 882 HOH B O   1 
HETATM 8774 O  O   . HOH IA 4 .   ? 31.73031 -5.51293  -45.35922 1.000 23.00937 ? 883 HOH B O   1 
HETATM 8775 O  O   . HOH IA 4 .   ? 37.35045 13.23130  -46.90357 1.000 17.73853 ? 884 HOH B O   1 
HETATM 8776 O  O   . HOH IA 4 .   ? 55.97152 -2.74382  -39.57507 1.000 23.57148 ? 885 HOH B O   1 
HETATM 8777 O  O   . HOH IA 4 .   ? 34.32124 28.66377  -65.58762 1.000 27.89639 ? 886 HOH B O   1 
HETATM 8778 O  O   . HOH IA 4 .   ? 26.11370 21.96295  -38.59482 1.000 18.82850 ? 887 HOH B O   1 
HETATM 8779 O  O   . HOH IA 4 .   ? 13.35878 -5.62829  -74.90795 1.000 31.74101 ? 888 HOH B O   1 
HETATM 8780 O  O   . HOH IA 4 .   ? 38.45571 -14.63091 -68.72040 1.000 29.49597 ? 889 HOH B O   1 
HETATM 8781 O  O   . HOH IA 4 .   ? 14.44391 22.26751  -61.63373 1.000 18.12692 ? 890 HOH B O   1 
HETATM 8782 O  O   . HOH IA 4 .   ? 51.42643 25.48896  -69.61754 1.000 27.10804 ? 891 HOH B O   1 
HETATM 8783 O  O   . HOH IA 4 .   ? 55.93859 10.76554  -64.16104 1.000 45.82145 ? 892 HOH B O   1 
HETATM 8784 O  O   . HOH IA 4 .   ? 14.91816 -9.70768  -51.62654 1.000 27.92063 ? 893 HOH B O   1 
HETATM 8785 O  O   . HOH IA 4 .   ? 46.86174 -4.10032  -41.84711 1.000 35.97008 ? 894 HOH B O   1 
HETATM 8786 O  O   . HOH IA 4 .   ? 52.99659 -8.71753  -60.02178 1.000 31.37299 ? 895 HOH B O   1 
HETATM 8787 O  O   . HOH IA 4 .   ? 41.39152 25.65731  -49.97249 1.000 28.59187 ? 896 HOH B O   1 
HETATM 8788 O  O   . HOH IA 4 .   ? 14.57121 6.76769   -52.99305 1.000 29.67183 ? 897 HOH B O   1 
HETATM 8789 O  O   . HOH IA 4 .   ? 51.11613 -17.04138 -46.71372 1.000 34.57200 ? 898 HOH B O   1 
HETATM 8790 O  O   . HOH IA 4 .   ? 43.93494 10.68917  -60.19554 1.000 24.22485 ? 899 HOH B O   1 
HETATM 8791 O  O   . HOH IA 4 .   ? 55.52541 6.78178   -38.90640 1.000 38.04423 ? 900 HOH B O   1 
HETATM 8792 O  O   . HOH IA 4 .   ? 55.05454 -14.83744 -54.88407 1.000 20.05325 ? 901 HOH B O   1 
HETATM 8793 O  O   . HOH IA 4 .   ? 42.61310 28.79869  -66.74478 1.000 34.13929 ? 902 HOH B O   1 
HETATM 8794 O  O   . HOH IA 4 .   ? 32.61413 -6.80173  -50.12330 1.000 18.90073 ? 903 HOH B O   1 
HETATM 8795 O  O   . HOH IA 4 .   ? 47.00065 -9.24556  -74.07200 1.000 20.52953 ? 904 HOH B O   1 
HETATM 8796 O  O   . HOH IA 4 .   ? 21.67101 -12.94224 -72.60412 1.000 32.08095 ? 905 HOH B O   1 
HETATM 8797 O  O   . HOH IA 4 .   ? 28.29406 35.92655  -75.37353 1.000 33.19540 ? 906 HOH B O   1 
HETATM 8798 O  O   . HOH IA 4 .   ? 56.05417 5.85408   -68.76607 1.000 23.61407 ? 907 HOH B O   1 
HETATM 8799 O  O   . HOH IA 4 .   ? 40.35932 28.52811  -66.43946 1.000 30.58977 ? 908 HOH B O   1 
HETATM 8800 O  O   . HOH IA 4 .   ? 13.59925 27.74283  -53.49033 1.000 17.13857 ? 909 HOH B O   1 
HETATM 8801 O  O   . HOH IA 4 .   ? 57.82742 9.00324   -63.61698 1.000 27.05890 ? 910 HOH B O   1 
HETATM 8802 O  O   . HOH IA 4 .   ? 12.008   12.669    -55.840   1.000 32.89178 ? 911 HOH B O   1 
HETATM 8803 O  O   . HOH IA 4 .   ? 17.361   26.416    -74.217   1.000 27.84897 ? 912 HOH B O   1 
HETATM 8804 O  O   . HOH IA 4 .   ? 40.45044 -12.10684 -42.96256 1.000 15.71894 ? 913 HOH B O   1 
HETATM 8805 O  O   . HOH IA 4 .   ? 27.50905 -8.46975  -52.05219 1.000 38.81421 ? 914 HOH B O   1 
HETATM 8806 O  O   . HOH IA 4 .   ? 28.88317 15.89793  -46.09903 1.000 29.17189 ? 915 HOH B O   1 
HETATM 8807 O  O   . HOH IA 4 .   ? 37.24316 23.63553  -65.44091 1.000 21.31249 ? 916 HOH B O   1 
HETATM 8808 O  O   . HOH IA 4 .   ? 31.34895 16.91002  -45.93732 1.000 26.61963 ? 917 HOH B O   1 
HETATM 8809 O  O   . HOH IA 4 .   ? 32.84337 19.97563  -41.84774 1.000 28.70264 ? 918 HOH B O   1 
HETATM 8810 O  O   . HOH IA 4 .   ? 58.92980 19.09058  -46.09303 1.000 38.30196 ? 919 HOH B O   1 
HETATM 8811 O  O   . HOH IA 4 .   ? 33.73890 -20.34762 -63.28409 1.000 29.13290 ? 920 HOH B O   1 
HETATM 8812 O  O   . HOH IA 4 .   ? 28.60214 4.20461   -47.57006 1.000 20.34694 ? 921 HOH B O   1 
HETATM 8813 O  O   . HOH IA 4 .   ? 36.28634 31.69207  -54.32135 1.000 26.58863 ? 922 HOH B O   1 
HETATM 8814 O  O   . HOH IA 4 .   ? 48.14908 -11.59715 -69.55028 1.000 16.96845 ? 923 HOH B O   1 
HETATM 8815 O  O   . HOH IA 4 .   ? 56.84961 6.59245   -63.28530 1.000 29.68798 ? 924 HOH B O   1 
HETATM 8816 O  O   . HOH IA 4 .   ? 56.08984 13.49573  -63.55482 1.000 32.00239 ? 925 HOH B O   1 
HETATM 8817 O  O   . HOH IA 4 .   ? 19.59508 17.99545  -37.13090 1.000 20.23084 ? 926 HOH B O   1 
HETATM 8818 O  O   . HOH IA 4 .   ? 24.38439 18.69820  -42.22799 1.000 24.60297 ? 927 HOH B O   1 
HETATM 8819 O  O   . HOH IA 4 .   ? 57.24891 -4.96559  -40.37683 1.000 35.79358 ? 928 HOH B O   1 
HETATM 8820 O  O   . HOH IA 4 .   ? 54.81406 16.07213  -42.25654 1.000 28.55212 ? 929 HOH B O   1 
HETATM 8821 O  O   . HOH IA 4 .   ? 56.36225 9.12315   -66.53579 1.000 27.61488 ? 930 HOH B O   1 
HETATM 8822 O  O   . HOH IA 4 .   ? 30.01635 -7.87812  -51.70665 1.000 36.38045 ? 931 HOH B O   1 
HETATM 8823 O  O   . HOH IA 4 .   ? 54.43328 -14.77450 -51.19953 1.000 25.28876 ? 932 HOH B O   1 
HETATM 8824 O  O   . HOH IA 4 .   ? 36.41071 -14.19045 -55.02335 1.000 42.55525 ? 933 HOH B O   1 
HETATM 8825 O  O   . HOH IA 4 .   ? 25.18231 2.93916   -48.85989 1.000 29.20289 ? 934 HOH B O   1 
HETATM 8826 O  O   . HOH IA 4 .   ? 23.62900 27.56832  -78.00184 1.000 32.70096 ? 935 HOH B O   1 
HETATM 8827 O  O   . HOH IA 4 .   ? 39.55351 24.11768  -63.92124 1.000 29.00162 ? 936 HOH B O   1 
HETATM 8828 O  O   . HOH IA 4 .   ? 51.58306 3.21579   -35.15973 1.000 36.39258 ? 937 HOH B O   1 
HETATM 8829 O  O   . HOH IA 4 .   ? 59.474   17.780    -67.299   1.000 41.11339 ? 938 HOH B O   1 
HETATM 8830 O  O   . HOH IA 4 .   ? 23.64624 6.87074   -88.50083 1.000 31.89567 ? 939 HOH B O   1 
HETATM 8831 O  O   . HOH IA 4 .   ? 33.45835 29.43193  -58.88632 1.000 37.72903 ? 940 HOH B O   1 
HETATM 8832 O  O   . HOH IA 4 .   ? 26.91751 17.16409  -79.30877 1.000 25.89651 ? 941 HOH B O   1 
HETATM 8833 O  O   . HOH IA 4 .   ? 19.82726 25.04307  -47.65598 1.000 19.63797 ? 942 HOH B O   1 
HETATM 8834 O  O   . HOH IA 4 .   ? 18.29902 32.40164  -76.83434 1.000 26.97181 ? 943 HOH B O   1 
HETATM 8835 O  O   . HOH IA 4 .   ? 19.35465 -7.30183  -79.53689 1.000 38.16814 ? 944 HOH B O   1 
HETATM 8836 O  O   . HOH IA 4 .   ? 55.60410 -1.00191  -37.08262 1.000 11.55433 ? 945 HOH B O   1 
HETATM 8837 O  O   . HOH IA 4 .   ? 20.68649 14.57222  -41.12546 1.000 22.03021 ? 946 HOH B O   1 
HETATM 8838 O  O   . HOH IA 4 .   ? 5.07512  -7.69534  -65.71783 1.000 33.68905 ? 947 HOH B O   1 
HETATM 8839 O  O   . HOH IA 4 .   ? 28.98157 40.09506  -62.44294 1.000 49.74146 ? 948 HOH B O   1 
HETATM 8840 O  O   . HOH IA 4 .   ? 55.07247 -5.02437  -39.54789 1.000 36.38157 ? 949 HOH B O   1 
HETATM 8841 O  O   . HOH IA 4 .   ? 23.39655 2.87776   -52.96828 1.000 21.08802 ? 950 HOH B O   1 
HETATM 8842 O  O   . HOH IA 4 .   ? 25.03428 14.25678  -42.95798 1.000 31.19319 ? 951 HOH B O   1 
HETATM 8843 O  O   . HOH IA 4 .   ? 29.85088 38.11555  -63.19395 1.000 35.54732 ? 952 HOH B O   1 
HETATM 8844 O  O   . HOH IA 4 .   ? 23.64381 25.69015  -79.68968 1.000 33.96941 ? 953 HOH B O   1 
HETATM 8845 O  O   . HOH IA 4 .   ? 8.25020  25.09310  -40.97787 1.000 19.15152 ? 954 HOH B O   1 
HETATM 8846 O  O   . HOH IA 4 .   ? 49.52924 -9.29203  -69.91786 1.000 21.94224 ? 955 HOH B O   1 
HETATM 8847 O  O   . HOH IA 4 .   ? 24.37389 11.43487  -43.13331 1.000 22.38872 ? 956 HOH B O   1 
HETATM 8848 O  O   . HOH IA 4 .   ? 25.79850 28.43863  -81.19372 1.000 34.64764 ? 957 HOH B O   1 
HETATM 8849 O  O   . HOH IA 4 .   ? 27.33232 -4.68843  -40.69732 1.000 20.51601 ? 958 HOH B O   1 
HETATM 8850 O  O   . HOH IA 4 .   ? 36.30840 31.06073  -51.68470 1.000 31.37235 ? 959 HOH B O   1 
HETATM 8851 O  O   . HOH IA 4 .   ? 27.71674 12.69537  -45.59366 1.000 23.94906 ? 960 HOH B O   1 
HETATM 8852 O  O   . HOH IA 4 .   ? 16.57749 1.44255   -80.16466 1.000 34.41297 ? 961 HOH B O   1 
HETATM 8853 O  O   . HOH IA 4 .   ? 21.05019 1.59515   -83.79904 1.000 27.13303 ? 962 HOH B O   1 
HETATM 8854 O  O   . HOH IA 4 .   ? 57.05373 -8.09529  -61.08650 1.000 35.60503 ? 963 HOH B O   1 
HETATM 8855 O  O   . HOH IA 4 .   ? 19.63553 2.61831   -81.72098 1.000 28.99006 ? 964 HOH B O   1 
HETATM 8856 O  O   . HOH IA 4 .   ? 31.13377 31.64679  -51.29157 1.000 36.27522 ? 965 HOH B O   1 
HETATM 8857 O  O   . HOH IA 4 .   ? 17.68396 -0.91135  -84.42818 1.000 33.57255 ? 966 HOH B O   1 
HETATM 8858 O  O   . HOH IA 4 .   ? 18.64977 -1.01628  -87.17518 1.000 23.64922 ? 967 HOH B O   1 
# 
