data_9BC1
# 
_entry.id   9BC1 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9BC1         pdb_00009bc1 10.2210/pdb9bc1/pdb 
WWPDB D_1000282309 ?            ?                   
# 
_pdbx_audit_revision_history.ordinal             1 
_pdbx_audit_revision_history.data_content_type   'Structure model' 
_pdbx_audit_revision_history.major_revision      1 
_pdbx_audit_revision_history.minor_revision      0 
_pdbx_audit_revision_history.revision_date       2025-04-23 
_pdbx_audit_revision_history.part_number         ? 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  REL 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9BC1 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-07 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_contact_author.id                 4 
_pdbx_contact_author.email              olsens@uthscsa.edu 
_pdbx_contact_author.name_first         Shaun 
_pdbx_contact_author.name_last          Olsen 
_pdbx_contact_author.name_mi            K 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-1265-7101 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Afsar, M.'    1 0000-0002-3062-9219 
'Priscila, B.' 2 0000-0003-3445-2649 
'Olsen, S.K.'  3 0000-0002-1265-7101 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   ? 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'To Be Published' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            0353 
_citation.journal_id_ISSN           ? 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            ? 
_citation.language                  ? 
_citation.page_first                ? 
_citation.page_last                 ? 
_citation.title                     'SARS-CoV-2 Mpro in complex with peptide mimetic inhibitor' 
_citation.year                      ? 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      ? 
_citation.pdbx_database_id_PubMed   ? 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Afsar, M.'    1 0000-0002-3062-9219 
primary 'Priscila, B.' 2 0000-0003-3445-2649 
primary 'Olsen, S.K.'  3 0000-0002-1265-7101 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer man '3C-like proteinase nsp5'   33825.547 2   3.4.22.69 ? ? ? 
2 polymer syn 'peptide mimetic inhibitor' 595.753   2   ?         ? ? ? 
3 water   nat water                       18.015    372 ?         ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        '3CL-PRO,3CLp,Main protease,Mpro,Non-structural protein 5,nsp5,SARS coronavirus main proteinase' 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no  
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
A,B ? 
2 'polypeptide(L)' no yes '(ACE)(ABA)(DTY)L(A1AMA)' XAYLX C,D ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        water 
_pdbx_entity_nonpoly.comp_id     HOH 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   SER   n 
1 2   GLY   n 
1 3   PHE   n 
1 4   ARG   n 
1 5   LYS   n 
1 6   MET   n 
1 7   ALA   n 
1 8   PHE   n 
1 9   PRO   n 
1 10  SER   n 
1 11  GLY   n 
1 12  LYS   n 
1 13  VAL   n 
1 14  GLU   n 
1 15  GLY   n 
1 16  CYS   n 
1 17  MET   n 
1 18  VAL   n 
1 19  GLN   n 
1 20  VAL   n 
1 21  THR   n 
1 22  CYS   n 
1 23  GLY   n 
1 24  THR   n 
1 25  THR   n 
1 26  THR   n 
1 27  LEU   n 
1 28  ASN   n 
1 29  GLY   n 
1 30  LEU   n 
1 31  TRP   n 
1 32  LEU   n 
1 33  ASP   n 
1 34  ASP   n 
1 35  VAL   n 
1 36  VAL   n 
1 37  TYR   n 
1 38  CYS   n 
1 39  PRO   n 
1 40  ARG   n 
1 41  HIS   n 
1 42  VAL   n 
1 43  ILE   n 
1 44  CYS   n 
1 45  THR   n 
1 46  SER   n 
1 47  GLU   n 
1 48  ASP   n 
1 49  MET   n 
1 50  LEU   n 
1 51  ASN   n 
1 52  PRO   n 
1 53  ASN   n 
1 54  TYR   n 
1 55  GLU   n 
1 56  ASP   n 
1 57  LEU   n 
1 58  LEU   n 
1 59  ILE   n 
1 60  ARG   n 
1 61  LYS   n 
1 62  SER   n 
1 63  ASN   n 
1 64  HIS   n 
1 65  ASN   n 
1 66  PHE   n 
1 67  LEU   n 
1 68  VAL   n 
1 69  GLN   n 
1 70  ALA   n 
1 71  GLY   n 
1 72  ASN   n 
1 73  VAL   n 
1 74  GLN   n 
1 75  LEU   n 
1 76  ARG   n 
1 77  VAL   n 
1 78  ILE   n 
1 79  GLY   n 
1 80  HIS   n 
1 81  SER   n 
1 82  MET   n 
1 83  GLN   n 
1 84  ASN   n 
1 85  CYS   n 
1 86  VAL   n 
1 87  LEU   n 
1 88  LYS   n 
1 89  LEU   n 
1 90  LYS   n 
1 91  VAL   n 
1 92  ASP   n 
1 93  THR   n 
1 94  ALA   n 
1 95  ASN   n 
1 96  PRO   n 
1 97  LYS   n 
1 98  THR   n 
1 99  PRO   n 
1 100 LYS   n 
1 101 TYR   n 
1 102 LYS   n 
1 103 PHE   n 
1 104 VAL   n 
1 105 ARG   n 
1 106 ILE   n 
1 107 GLN   n 
1 108 PRO   n 
1 109 GLY   n 
1 110 GLN   n 
1 111 THR   n 
1 112 PHE   n 
1 113 SER   n 
1 114 VAL   n 
1 115 LEU   n 
1 116 ALA   n 
1 117 CYS   n 
1 118 TYR   n 
1 119 ASN   n 
1 120 GLY   n 
1 121 SER   n 
1 122 PRO   n 
1 123 SER   n 
1 124 GLY   n 
1 125 VAL   n 
1 126 TYR   n 
1 127 GLN   n 
1 128 CYS   n 
1 129 ALA   n 
1 130 MET   n 
1 131 ARG   n 
1 132 PRO   n 
1 133 ASN   n 
1 134 PHE   n 
1 135 THR   n 
1 136 ILE   n 
1 137 LYS   n 
1 138 GLY   n 
1 139 SER   n 
1 140 PHE   n 
1 141 LEU   n 
1 142 ASN   n 
1 143 GLY   n 
1 144 SER   n 
1 145 CYS   n 
1 146 GLY   n 
1 147 SER   n 
1 148 VAL   n 
1 149 GLY   n 
1 150 PHE   n 
1 151 ASN   n 
1 152 ILE   n 
1 153 ASP   n 
1 154 TYR   n 
1 155 ASP   n 
1 156 CYS   n 
1 157 VAL   n 
1 158 SER   n 
1 159 PHE   n 
1 160 CYS   n 
1 161 TYR   n 
1 162 MET   n 
1 163 HIS   n 
1 164 HIS   n 
1 165 MET   n 
1 166 GLU   n 
1 167 LEU   n 
1 168 PRO   n 
1 169 THR   n 
1 170 GLY   n 
1 171 VAL   n 
1 172 HIS   n 
1 173 ALA   n 
1 174 GLY   n 
1 175 THR   n 
1 176 ASP   n 
1 177 LEU   n 
1 178 GLU   n 
1 179 GLY   n 
1 180 ASN   n 
1 181 PHE   n 
1 182 TYR   n 
1 183 GLY   n 
1 184 PRO   n 
1 185 PHE   n 
1 186 VAL   n 
1 187 ASP   n 
1 188 ARG   n 
1 189 GLN   n 
1 190 THR   n 
1 191 ALA   n 
1 192 GLN   n 
1 193 ALA   n 
1 194 ALA   n 
1 195 GLY   n 
1 196 THR   n 
1 197 ASP   n 
1 198 THR   n 
1 199 THR   n 
1 200 ILE   n 
1 201 THR   n 
1 202 VAL   n 
1 203 ASN   n 
1 204 VAL   n 
1 205 LEU   n 
1 206 ALA   n 
1 207 TRP   n 
1 208 LEU   n 
1 209 TYR   n 
1 210 ALA   n 
1 211 ALA   n 
1 212 VAL   n 
1 213 ILE   n 
1 214 ASN   n 
1 215 GLY   n 
1 216 ASP   n 
1 217 ARG   n 
1 218 TRP   n 
1 219 PHE   n 
1 220 LEU   n 
1 221 ASN   n 
1 222 ARG   n 
1 223 PHE   n 
1 224 THR   n 
1 225 THR   n 
1 226 THR   n 
1 227 LEU   n 
1 228 ASN   n 
1 229 ASP   n 
1 230 PHE   n 
1 231 ASN   n 
1 232 LEU   n 
1 233 VAL   n 
1 234 ALA   n 
1 235 MET   n 
1 236 LYS   n 
1 237 TYR   n 
1 238 ASN   n 
1 239 TYR   n 
1 240 GLU   n 
1 241 PRO   n 
1 242 LEU   n 
1 243 THR   n 
1 244 GLN   n 
1 245 ASP   n 
1 246 HIS   n 
1 247 VAL   n 
1 248 ASP   n 
1 249 ILE   n 
1 250 LEU   n 
1 251 GLY   n 
1 252 PRO   n 
1 253 LEU   n 
1 254 SER   n 
1 255 ALA   n 
1 256 GLN   n 
1 257 THR   n 
1 258 GLY   n 
1 259 ILE   n 
1 260 ALA   n 
1 261 VAL   n 
1 262 LEU   n 
1 263 ASP   n 
1 264 MET   n 
1 265 CYS   n 
1 266 ALA   n 
1 267 SER   n 
1 268 LEU   n 
1 269 LYS   n 
1 270 GLU   n 
1 271 LEU   n 
1 272 LEU   n 
1 273 GLN   n 
1 274 ASN   n 
1 275 GLY   n 
1 276 MET   n 
1 277 ASN   n 
1 278 GLY   n 
1 279 ARG   n 
1 280 THR   n 
1 281 ILE   n 
1 282 LEU   n 
1 283 GLY   n 
1 284 SER   n 
1 285 ALA   n 
1 286 LEU   n 
1 287 LEU   n 
1 288 GLU   n 
1 289 ASP   n 
1 290 GLU   n 
1 291 PHE   n 
1 292 THR   n 
1 293 PRO   n 
1 294 PHE   n 
1 295 ASP   n 
1 296 VAL   n 
1 297 VAL   n 
1 298 ARG   n 
1 299 GLN   n 
1 300 CYS   n 
1 301 SER   n 
1 302 GLY   n 
1 303 VAL   n 
1 304 THR   n 
1 305 PHE   n 
1 306 GLN   n 
2 1   ACE   n 
2 2   ABA   n 
2 3   DTY   n 
2 4   LEU   n 
2 5   A1AMA n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   306 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'rep, 1a-1b' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Severe acute respiratory syndrome coronavirus 2' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     2697049 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      
;Escherichia coli 'BL21-Gold(DE3)pLysS AG'
;
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     866768 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_src_syn.entity_id              2 
_pdbx_entity_src_syn.pdbx_src_id            1 
_pdbx_entity_src_syn.pdbx_alt_source_flag   sample 
_pdbx_entity_src_syn.pdbx_beg_seq_num       1 
_pdbx_entity_src_syn.pdbx_end_seq_num       5 
_pdbx_entity_src_syn.organism_scientific    'synthetic construct' 
_pdbx_entity_src_syn.organism_common_name   ? 
_pdbx_entity_src_syn.ncbi_taxonomy_id       32630 
_pdbx_entity_src_syn.details                ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AMA non-polymer         . '(4S)-4-amino-6-(methanesulfonyl)hexanamide' ? 'C7 H16 N2 O3 S' 208.279 
ABA   'L-peptide linking' n 'ALPHA-AMINOBUTYRIC ACID'                    ? 'C4 H9 N O2'     103.120 
ACE   non-polymer         . 'ACETYL GROUP'                               ? 'C2 H4 O'        44.053  
ALA   'L-peptide linking' y ALANINE                                      ? 'C3 H7 N O2'     89.093  
ARG   'L-peptide linking' y ARGININE                                     ? 'C6 H15 N4 O2 1' 175.209 
ASN   'L-peptide linking' y ASPARAGINE                                   ? 'C4 H8 N2 O3'    132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID'                              ? 'C4 H7 N O4'     133.103 
CYS   'L-peptide linking' y CYSTEINE                                     ? 'C3 H7 N O2 S'   121.158 
DTY   'D-peptide linking' . D-TYROSINE                                   ? 'C9 H11 N O3'    181.189 
GLN   'L-peptide linking' y GLUTAMINE                                    ? 'C5 H10 N2 O3'   146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID'                              ? 'C5 H9 N O4'     147.129 
GLY   'peptide linking'   y GLYCINE                                      ? 'C2 H5 N O2'     75.067  
HIS   'L-peptide linking' y HISTIDINE                                    ? 'C6 H10 N3 O2 1' 156.162 
HOH   non-polymer         . WATER                                        ? 'H2 O'           18.015  
ILE   'L-peptide linking' y ISOLEUCINE                                   ? 'C6 H13 N O2'    131.173 
LEU   'L-peptide linking' y LEUCINE                                      ? 'C6 H13 N O2'    131.173 
LYS   'L-peptide linking' y LYSINE                                       ? 'C6 H15 N2 O2 1' 147.195 
MET   'L-peptide linking' y METHIONINE                                   ? 'C5 H11 N O2 S'  149.211 
PHE   'L-peptide linking' y PHENYLALANINE                                ? 'C9 H11 N O2'    165.189 
PRO   'L-peptide linking' y PROLINE                                      ? 'C5 H9 N O2'     115.130 
SER   'L-peptide linking' y SERINE                                       ? 'C3 H7 N O3'     105.093 
THR   'L-peptide linking' y THREONINE                                    ? 'C4 H9 N O3'     119.119 
TRP   'L-peptide linking' y TRYPTOPHAN                                   ? 'C11 H12 N2 O2'  204.225 
TYR   'L-peptide linking' y TYROSINE                                     ? 'C9 H11 N O3'    181.189 
VAL   'L-peptide linking' y VALINE                                       ? 'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   SER   1   1   ?   ?     ?   A . n 
A 1 2   GLY   2   2   2   GLY   GLY A . n 
A 1 3   PHE   3   3   3   PHE   PHE A . n 
A 1 4   ARG   4   4   4   ARG   ARG A . n 
A 1 5   LYS   5   5   5   LYS   LYS A . n 
A 1 6   MET   6   6   6   MET   MET A . n 
A 1 7   ALA   7   7   7   ALA   ALA A . n 
A 1 8   PHE   8   8   8   PHE   PHE A . n 
A 1 9   PRO   9   9   9   PRO   PRO A . n 
A 1 10  SER   10  10  10  SER   SER A . n 
A 1 11  GLY   11  11  11  GLY   GLY A . n 
A 1 12  LYS   12  12  12  LYS   LYS A . n 
A 1 13  VAL   13  13  13  VAL   VAL A . n 
A 1 14  GLU   14  14  14  GLU   GLU A . n 
A 1 15  GLY   15  15  15  GLY   GLY A . n 
A 1 16  CYS   16  16  16  CYS   CYS A . n 
A 1 17  MET   17  17  17  MET   MET A . n 
A 1 18  VAL   18  18  18  VAL   VAL A . n 
A 1 19  GLN   19  19  19  GLN   GLN A . n 
A 1 20  VAL   20  20  20  VAL   VAL A . n 
A 1 21  THR   21  21  21  THR   THR A . n 
A 1 22  CYS   22  22  22  CYS   CYS A . n 
A 1 23  GLY   23  23  23  GLY   GLY A . n 
A 1 24  THR   24  24  24  THR   THR A . n 
A 1 25  THR   25  25  25  THR   THR A . n 
A 1 26  THR   26  26  26  THR   THR A . n 
A 1 27  LEU   27  27  27  LEU   LEU A . n 
A 1 28  ASN   28  28  28  ASN   ASN A . n 
A 1 29  GLY   29  29  29  GLY   GLY A . n 
A 1 30  LEU   30  30  30  LEU   LEU A . n 
A 1 31  TRP   31  31  31  TRP   TRP A . n 
A 1 32  LEU   32  32  32  LEU   LEU A . n 
A 1 33  ASP   33  33  33  ASP   ASP A . n 
A 1 34  ASP   34  34  34  ASP   ASP A . n 
A 1 35  VAL   35  35  35  VAL   VAL A . n 
A 1 36  VAL   36  36  36  VAL   VAL A . n 
A 1 37  TYR   37  37  37  TYR   TYR A . n 
A 1 38  CYS   38  38  38  CYS   CYS A . n 
A 1 39  PRO   39  39  39  PRO   PRO A . n 
A 1 40  ARG   40  40  40  ARG   ARG A . n 
A 1 41  HIS   41  41  41  HIS   HIS A . n 
A 1 42  VAL   42  42  42  VAL   VAL A . n 
A 1 43  ILE   43  43  43  ILE   ILE A . n 
A 1 44  CYS   44  44  44  CYS   CYS A . n 
A 1 45  THR   45  45  45  THR   THR A . n 
A 1 46  SER   46  46  46  SER   SER A . n 
A 1 47  GLU   47  47  47  GLU   GLU A . n 
A 1 48  ASP   48  48  48  ASP   ASP A . n 
A 1 49  MET   49  49  49  MET   MET A . n 
A 1 50  LEU   50  50  50  LEU   LEU A . n 
A 1 51  ASN   51  51  51  ASN   ASN A . n 
A 1 52  PRO   52  52  52  PRO   PRO A . n 
A 1 53  ASN   53  53  53  ASN   ASN A . n 
A 1 54  TYR   54  54  54  TYR   TYR A . n 
A 1 55  GLU   55  55  55  GLU   GLU A . n 
A 1 56  ASP   56  56  56  ASP   ASP A . n 
A 1 57  LEU   57  57  57  LEU   LEU A . n 
A 1 58  LEU   58  58  58  LEU   LEU A . n 
A 1 59  ILE   59  59  59  ILE   ILE A . n 
A 1 60  ARG   60  60  60  ARG   ARG A . n 
A 1 61  LYS   61  61  61  LYS   LYS A . n 
A 1 62  SER   62  62  62  SER   SER A . n 
A 1 63  ASN   63  63  63  ASN   ASN A . n 
A 1 64  HIS   64  64  64  HIS   HIS A . n 
A 1 65  ASN   65  65  65  ASN   ASN A . n 
A 1 66  PHE   66  66  66  PHE   PHE A . n 
A 1 67  LEU   67  67  67  LEU   LEU A . n 
A 1 68  VAL   68  68  68  VAL   VAL A . n 
A 1 69  GLN   69  69  69  GLN   GLN A . n 
A 1 70  ALA   70  70  70  ALA   ALA A . n 
A 1 71  GLY   71  71  71  GLY   GLY A . n 
A 1 72  ASN   72  72  72  ASN   ASN A . n 
A 1 73  VAL   73  73  73  VAL   VAL A . n 
A 1 74  GLN   74  74  74  GLN   GLN A . n 
A 1 75  LEU   75  75  75  LEU   LEU A . n 
A 1 76  ARG   76  76  76  ARG   ARG A . n 
A 1 77  VAL   77  77  77  VAL   VAL A . n 
A 1 78  ILE   78  78  78  ILE   ILE A . n 
A 1 79  GLY   79  79  79  GLY   GLY A . n 
A 1 80  HIS   80  80  80  HIS   HIS A . n 
A 1 81  SER   81  81  81  SER   SER A . n 
A 1 82  MET   82  82  82  MET   MET A . n 
A 1 83  GLN   83  83  83  GLN   GLN A . n 
A 1 84  ASN   84  84  84  ASN   ASN A . n 
A 1 85  CYS   85  85  85  CYS   CYS A . n 
A 1 86  VAL   86  86  86  VAL   VAL A . n 
A 1 87  LEU   87  87  87  LEU   LEU A . n 
A 1 88  LYS   88  88  88  LYS   LYS A . n 
A 1 89  LEU   89  89  89  LEU   LEU A . n 
A 1 90  LYS   90  90  90  LYS   LYS A . n 
A 1 91  VAL   91  91  91  VAL   VAL A . n 
A 1 92  ASP   92  92  92  ASP   ASP A . n 
A 1 93  THR   93  93  93  THR   THR A . n 
A 1 94  ALA   94  94  94  ALA   ALA A . n 
A 1 95  ASN   95  95  95  ASN   ASN A . n 
A 1 96  PRO   96  96  96  PRO   PRO A . n 
A 1 97  LYS   97  97  97  LYS   LYS A . n 
A 1 98  THR   98  98  98  THR   THR A . n 
A 1 99  PRO   99  99  99  PRO   PRO A . n 
A 1 100 LYS   100 100 100 LYS   LYS A . n 
A 1 101 TYR   101 101 101 TYR   TYR A . n 
A 1 102 LYS   102 102 102 LYS   LYS A . n 
A 1 103 PHE   103 103 103 PHE   PHE A . n 
A 1 104 VAL   104 104 104 VAL   VAL A . n 
A 1 105 ARG   105 105 105 ARG   ARG A . n 
A 1 106 ILE   106 106 106 ILE   ILE A . n 
A 1 107 GLN   107 107 107 GLN   GLN A . n 
A 1 108 PRO   108 108 108 PRO   PRO A . n 
A 1 109 GLY   109 109 109 GLY   GLY A . n 
A 1 110 GLN   110 110 110 GLN   GLN A . n 
A 1 111 THR   111 111 111 THR   THR A . n 
A 1 112 PHE   112 112 112 PHE   PHE A . n 
A 1 113 SER   113 113 113 SER   SER A . n 
A 1 114 VAL   114 114 114 VAL   VAL A . n 
A 1 115 LEU   115 115 115 LEU   LEU A . n 
A 1 116 ALA   116 116 116 ALA   ALA A . n 
A 1 117 CYS   117 117 117 CYS   CYS A . n 
A 1 118 TYR   118 118 118 TYR   TYR A . n 
A 1 119 ASN   119 119 119 ASN   ASN A . n 
A 1 120 GLY   120 120 120 GLY   GLY A . n 
A 1 121 SER   121 121 121 SER   SER A . n 
A 1 122 PRO   122 122 122 PRO   PRO A . n 
A 1 123 SER   123 123 123 SER   SER A . n 
A 1 124 GLY   124 124 124 GLY   GLY A . n 
A 1 125 VAL   125 125 125 VAL   VAL A . n 
A 1 126 TYR   126 126 126 TYR   TYR A . n 
A 1 127 GLN   127 127 127 GLN   GLN A . n 
A 1 128 CYS   128 128 128 CYS   CYS A . n 
A 1 129 ALA   129 129 129 ALA   ALA A . n 
A 1 130 MET   130 130 130 MET   MET A . n 
A 1 131 ARG   131 131 131 ARG   ARG A . n 
A 1 132 PRO   132 132 132 PRO   PRO A . n 
A 1 133 ASN   133 133 133 ASN   ASN A . n 
A 1 134 PHE   134 134 134 PHE   PHE A . n 
A 1 135 THR   135 135 135 THR   THR A . n 
A 1 136 ILE   136 136 136 ILE   ILE A . n 
A 1 137 LYS   137 137 137 LYS   LYS A . n 
A 1 138 GLY   138 138 138 GLY   GLY A . n 
A 1 139 SER   139 139 139 SER   SER A . n 
A 1 140 PHE   140 140 140 PHE   PHE A . n 
A 1 141 LEU   141 141 141 LEU   LEU A . n 
A 1 142 ASN   142 142 142 ASN   ASN A . n 
A 1 143 GLY   143 143 143 GLY   GLY A . n 
A 1 144 SER   144 144 144 SER   SER A . n 
A 1 145 CYS   145 145 145 CYS   CYS A . n 
A 1 146 GLY   146 146 146 GLY   GLY A . n 
A 1 147 SER   147 147 147 SER   SER A . n 
A 1 148 VAL   148 148 148 VAL   VAL A . n 
A 1 149 GLY   149 149 149 GLY   GLY A . n 
A 1 150 PHE   150 150 150 PHE   PHE A . n 
A 1 151 ASN   151 151 151 ASN   ASN A . n 
A 1 152 ILE   152 152 152 ILE   ILE A . n 
A 1 153 ASP   153 153 153 ASP   ASP A . n 
A 1 154 TYR   154 154 154 TYR   ALA A . n 
A 1 155 ASP   155 155 155 ASP   ASP A . n 
A 1 156 CYS   156 156 156 CYS   CYS A . n 
A 1 157 VAL   157 157 157 VAL   VAL A . n 
A 1 158 SER   158 158 158 SER   SER A . n 
A 1 159 PHE   159 159 159 PHE   PHE A . n 
A 1 160 CYS   160 160 160 CYS   CYS A . n 
A 1 161 TYR   161 161 161 TYR   TYR A . n 
A 1 162 MET   162 162 162 MET   MET A . n 
A 1 163 HIS   163 163 163 HIS   HIS A . n 
A 1 164 HIS   164 164 164 HIS   HIS A . n 
A 1 165 MET   165 165 165 MET   MET A . n 
A 1 166 GLU   166 166 166 GLU   GLU A . n 
A 1 167 LEU   167 167 167 LEU   LEU A . n 
A 1 168 PRO   168 168 168 PRO   PRO A . n 
A 1 169 THR   169 169 169 THR   THR A . n 
A 1 170 GLY   170 170 170 GLY   GLY A . n 
A 1 171 VAL   171 171 171 VAL   VAL A . n 
A 1 172 HIS   172 172 172 HIS   HIS A . n 
A 1 173 ALA   173 173 173 ALA   ALA A . n 
A 1 174 GLY   174 174 174 GLY   GLY A . n 
A 1 175 THR   175 175 175 THR   THR A . n 
A 1 176 ASP   176 176 176 ASP   ASP A . n 
A 1 177 LEU   177 177 177 LEU   LEU A . n 
A 1 178 GLU   178 178 178 GLU   GLU A . n 
A 1 179 GLY   179 179 179 GLY   GLY A . n 
A 1 180 ASN   180 180 180 ASN   ASN A . n 
A 1 181 PHE   181 181 181 PHE   PHE A . n 
A 1 182 TYR   182 182 182 TYR   TYR A . n 
A 1 183 GLY   183 183 183 GLY   GLY A . n 
A 1 184 PRO   184 184 184 PRO   PRO A . n 
A 1 185 PHE   185 185 185 PHE   PHE A . n 
A 1 186 VAL   186 186 186 VAL   VAL A . n 
A 1 187 ASP   187 187 187 ASP   ASP A . n 
A 1 188 ARG   188 188 188 ARG   ARG A . n 
A 1 189 GLN   189 189 189 GLN   GLN A . n 
A 1 190 THR   190 190 190 THR   THR A . n 
A 1 191 ALA   191 191 191 ALA   ALA A . n 
A 1 192 GLN   192 192 192 GLN   GLN A . n 
A 1 193 ALA   193 193 193 ALA   ALA A . n 
A 1 194 ALA   194 194 194 ALA   ALA A . n 
A 1 195 GLY   195 195 195 GLY   GLY A . n 
A 1 196 THR   196 196 196 THR   THR A . n 
A 1 197 ASP   197 197 197 ASP   ASP A . n 
A 1 198 THR   198 198 198 THR   THR A . n 
A 1 199 THR   199 199 199 THR   THR A . n 
A 1 200 ILE   200 200 200 ILE   ILE A . n 
A 1 201 THR   201 201 201 THR   THR A . n 
A 1 202 VAL   202 202 202 VAL   VAL A . n 
A 1 203 ASN   203 203 203 ASN   ASN A . n 
A 1 204 VAL   204 204 204 VAL   VAL A . n 
A 1 205 LEU   205 205 205 LEU   LEU A . n 
A 1 206 ALA   206 206 206 ALA   ALA A . n 
A 1 207 TRP   207 207 207 TRP   TRP A . n 
A 1 208 LEU   208 208 208 LEU   LEU A . n 
A 1 209 TYR   209 209 209 TYR   TYR A . n 
A 1 210 ALA   210 210 210 ALA   ALA A . n 
A 1 211 ALA   211 211 211 ALA   ALA A . n 
A 1 212 VAL   212 212 212 VAL   VAL A . n 
A 1 213 ILE   213 213 213 ILE   ILE A . n 
A 1 214 ASN   214 214 214 ASN   ASN A . n 
A 1 215 GLY   215 215 215 GLY   GLY A . n 
A 1 216 ASP   216 216 216 ASP   ASP A . n 
A 1 217 ARG   217 217 217 ARG   ARG A . n 
A 1 218 TRP   218 218 218 TRP   TRP A . n 
A 1 219 PHE   219 219 219 PHE   PHE A . n 
A 1 220 LEU   220 220 220 LEU   LEU A . n 
A 1 221 ASN   221 221 221 ASN   ASN A . n 
A 1 222 ARG   222 222 222 ARG   ALA A . n 
A 1 223 PHE   223 223 223 PHE   PHE A . n 
A 1 224 THR   224 224 224 THR   THR A . n 
A 1 225 THR   225 225 225 THR   THR A . n 
A 1 226 THR   226 226 226 THR   THR A . n 
A 1 227 LEU   227 227 227 LEU   LEU A . n 
A 1 228 ASN   228 228 228 ASN   ASN A . n 
A 1 229 ASP   229 229 229 ASP   ASP A . n 
A 1 230 PHE   230 230 230 PHE   PHE A . n 
A 1 231 ASN   231 231 231 ASN   ASN A . n 
A 1 232 LEU   232 232 232 LEU   LEU A . n 
A 1 233 VAL   233 233 233 VAL   VAL A . n 
A 1 234 ALA   234 234 234 ALA   ALA A . n 
A 1 235 MET   235 235 235 MET   MET A . n 
A 1 236 LYS   236 236 236 LYS   LYS A . n 
A 1 237 TYR   237 237 237 TYR   TYR A . n 
A 1 238 ASN   238 238 238 ASN   ASN A . n 
A 1 239 TYR   239 239 239 TYR   TYR A . n 
A 1 240 GLU   240 240 240 GLU   GLU A . n 
A 1 241 PRO   241 241 241 PRO   PRO A . n 
A 1 242 LEU   242 242 242 LEU   LEU A . n 
A 1 243 THR   243 243 243 THR   THR A . n 
A 1 244 GLN   244 244 244 GLN   GLN A . n 
A 1 245 ASP   245 245 245 ASP   ASP A . n 
A 1 246 HIS   246 246 246 HIS   HIS A . n 
A 1 247 VAL   247 247 247 VAL   VAL A . n 
A 1 248 ASP   248 248 248 ASP   ASP A . n 
A 1 249 ILE   249 249 249 ILE   ILE A . n 
A 1 250 LEU   250 250 250 LEU   LEU A . n 
A 1 251 GLY   251 251 251 GLY   GLY A . n 
A 1 252 PRO   252 252 252 PRO   PRO A . n 
A 1 253 LEU   253 253 253 LEU   LEU A . n 
A 1 254 SER   254 254 254 SER   SER A . n 
A 1 255 ALA   255 255 255 ALA   ALA A . n 
A 1 256 GLN   256 256 256 GLN   GLN A . n 
A 1 257 THR   257 257 257 THR   THR A . n 
A 1 258 GLY   258 258 258 GLY   GLY A . n 
A 1 259 ILE   259 259 259 ILE   ILE A . n 
A 1 260 ALA   260 260 260 ALA   ALA A . n 
A 1 261 VAL   261 261 261 VAL   VAL A . n 
A 1 262 LEU   262 262 262 LEU   LEU A . n 
A 1 263 ASP   263 263 263 ASP   ASP A . n 
A 1 264 MET   264 264 264 MET   MET A . n 
A 1 265 CYS   265 265 265 CYS   CYS A . n 
A 1 266 ALA   266 266 266 ALA   ALA A . n 
A 1 267 SER   267 267 267 SER   SER A . n 
A 1 268 LEU   268 268 268 LEU   LEU A . n 
A 1 269 LYS   269 269 269 LYS   LYS A . n 
A 1 270 GLU   270 270 270 GLU   GLU A . n 
A 1 271 LEU   271 271 271 LEU   LEU A . n 
A 1 272 LEU   272 272 272 LEU   LEU A . n 
A 1 273 GLN   273 273 273 GLN   GLN A . n 
A 1 274 ASN   274 274 274 ASN   ASN A . n 
A 1 275 GLY   275 275 275 GLY   GLY A . n 
A 1 276 MET   276 276 276 MET   MET A . n 
A 1 277 ASN   277 277 277 ASN   ASN A . n 
A 1 278 GLY   278 278 278 GLY   GLY A . n 
A 1 279 ARG   279 279 279 ARG   ARG A . n 
A 1 280 THR   280 280 280 THR   THR A . n 
A 1 281 ILE   281 281 281 ILE   ILE A . n 
A 1 282 LEU   282 282 282 LEU   LEU A . n 
A 1 283 GLY   283 283 283 GLY   GLY A . n 
A 1 284 SER   284 284 284 SER   SER A . n 
A 1 285 ALA   285 285 285 ALA   ALA A . n 
A 1 286 LEU   286 286 286 LEU   LEU A . n 
A 1 287 LEU   287 287 287 LEU   LEU A . n 
A 1 288 GLU   288 288 288 GLU   GLU A . n 
A 1 289 ASP   289 289 289 ASP   ASP A . n 
A 1 290 GLU   290 290 290 GLU   GLU A . n 
A 1 291 PHE   291 291 291 PHE   PHE A . n 
A 1 292 THR   292 292 292 THR   THR A . n 
A 1 293 PRO   293 293 293 PRO   PRO A . n 
A 1 294 PHE   294 294 294 PHE   ALA A . n 
A 1 295 ASP   295 295 295 ASP   ASP A . n 
A 1 296 VAL   296 296 296 VAL   VAL A . n 
A 1 297 VAL   297 297 297 VAL   VAL A . n 
A 1 298 ARG   298 298 298 ARG   ARG A . n 
A 1 299 GLN   299 299 299 GLN   GLN A . n 
A 1 300 CYS   300 300 300 CYS   CYS A . n 
A 1 301 SER   301 301 301 SER   SER A . n 
A 1 302 GLY   302 302 302 GLY   GLY A . n 
A 1 303 VAL   303 303 303 VAL   VAL A . n 
A 1 304 THR   304 304 ?   ?     ?   A . n 
A 1 305 PHE   305 305 ?   ?     ?   A . n 
A 1 306 GLN   306 306 ?   ?     ?   A . n 
B 1 1   SER   1   1   1   SER   SER B . n 
B 1 2   GLY   2   2   2   GLY   GLY B . n 
B 1 3   PHE   3   3   3   PHE   PHE B . n 
B 1 4   ARG   4   4   4   ARG   ARG B . n 
B 1 5   LYS   5   5   5   LYS   LYS B . n 
B 1 6   MET   6   6   6   MET   MET B . n 
B 1 7   ALA   7   7   7   ALA   ALA B . n 
B 1 8   PHE   8   8   8   PHE   PHE B . n 
B 1 9   PRO   9   9   9   PRO   PRO B . n 
B 1 10  SER   10  10  10  SER   SER B . n 
B 1 11  GLY   11  11  11  GLY   GLY B . n 
B 1 12  LYS   12  12  12  LYS   LYS B . n 
B 1 13  VAL   13  13  13  VAL   VAL B . n 
B 1 14  GLU   14  14  14  GLU   GLU B . n 
B 1 15  GLY   15  15  15  GLY   GLY B . n 
B 1 16  CYS   16  16  16  CYS   CYS B . n 
B 1 17  MET   17  17  17  MET   MET B . n 
B 1 18  VAL   18  18  18  VAL   VAL B . n 
B 1 19  GLN   19  19  19  GLN   GLN B . n 
B 1 20  VAL   20  20  20  VAL   VAL B . n 
B 1 21  THR   21  21  21  THR   THR B . n 
B 1 22  CYS   22  22  22  CYS   CYS B . n 
B 1 23  GLY   23  23  23  GLY   GLY B . n 
B 1 24  THR   24  24  24  THR   THR B . n 
B 1 25  THR   25  25  25  THR   THR B . n 
B 1 26  THR   26  26  26  THR   THR B . n 
B 1 27  LEU   27  27  27  LEU   LEU B . n 
B 1 28  ASN   28  28  28  ASN   ASN B . n 
B 1 29  GLY   29  29  29  GLY   GLY B . n 
B 1 30  LEU   30  30  30  LEU   LEU B . n 
B 1 31  TRP   31  31  31  TRP   TRP B . n 
B 1 32  LEU   32  32  32  LEU   LEU B . n 
B 1 33  ASP   33  33  33  ASP   ASP B . n 
B 1 34  ASP   34  34  34  ASP   ASP B . n 
B 1 35  VAL   35  35  35  VAL   VAL B . n 
B 1 36  VAL   36  36  36  VAL   VAL B . n 
B 1 37  TYR   37  37  37  TYR   TYR B . n 
B 1 38  CYS   38  38  38  CYS   CYS B . n 
B 1 39  PRO   39  39  39  PRO   PRO B . n 
B 1 40  ARG   40  40  40  ARG   ARG B . n 
B 1 41  HIS   41  41  41  HIS   HIS B . n 
B 1 42  VAL   42  42  42  VAL   VAL B . n 
B 1 43  ILE   43  43  43  ILE   ILE B . n 
B 1 44  CYS   44  44  44  CYS   CYS B . n 
B 1 45  THR   45  45  45  THR   THR B . n 
B 1 46  SER   46  46  46  SER   SER B . n 
B 1 47  GLU   47  47  47  GLU   GLU B . n 
B 1 48  ASP   48  48  48  ASP   ASP B . n 
B 1 49  MET   49  49  49  MET   MET B . n 
B 1 50  LEU   50  50  50  LEU   LEU B . n 
B 1 51  ASN   51  51  51  ASN   ASN B . n 
B 1 52  PRO   52  52  52  PRO   PRO B . n 
B 1 53  ASN   53  53  53  ASN   ASN B . n 
B 1 54  TYR   54  54  54  TYR   TYR B . n 
B 1 55  GLU   55  55  55  GLU   GLU B . n 
B 1 56  ASP   56  56  56  ASP   ASP B . n 
B 1 57  LEU   57  57  57  LEU   LEU B . n 
B 1 58  LEU   58  58  58  LEU   LEU B . n 
B 1 59  ILE   59  59  59  ILE   ILE B . n 
B 1 60  ARG   60  60  60  ARG   ARG B . n 
B 1 61  LYS   61  61  61  LYS   LYS B . n 
B 1 62  SER   62  62  62  SER   SER B . n 
B 1 63  ASN   63  63  63  ASN   ASN B . n 
B 1 64  HIS   64  64  64  HIS   HIS B . n 
B 1 65  ASN   65  65  65  ASN   ASN B . n 
B 1 66  PHE   66  66  66  PHE   PHE B . n 
B 1 67  LEU   67  67  67  LEU   LEU B . n 
B 1 68  VAL   68  68  68  VAL   VAL B . n 
B 1 69  GLN   69  69  69  GLN   GLN B . n 
B 1 70  ALA   70  70  70  ALA   ALA B . n 
B 1 71  GLY   71  71  71  GLY   GLY B . n 
B 1 72  ASN   72  72  72  ASN   ASN B . n 
B 1 73  VAL   73  73  73  VAL   VAL B . n 
B 1 74  GLN   74  74  74  GLN   GLN B . n 
B 1 75  LEU   75  75  75  LEU   LEU B . n 
B 1 76  ARG   76  76  76  ARG   ARG B . n 
B 1 77  VAL   77  77  77  VAL   VAL B . n 
B 1 78  ILE   78  78  78  ILE   ILE B . n 
B 1 79  GLY   79  79  79  GLY   GLY B . n 
B 1 80  HIS   80  80  80  HIS   HIS B . n 
B 1 81  SER   81  81  81  SER   SER B . n 
B 1 82  MET   82  82  82  MET   MET B . n 
B 1 83  GLN   83  83  83  GLN   GLN B . n 
B 1 84  ASN   84  84  84  ASN   ASN B . n 
B 1 85  CYS   85  85  85  CYS   CYS B . n 
B 1 86  VAL   86  86  86  VAL   VAL B . n 
B 1 87  LEU   87  87  87  LEU   LEU B . n 
B 1 88  LYS   88  88  88  LYS   LYS B . n 
B 1 89  LEU   89  89  89  LEU   LEU B . n 
B 1 90  LYS   90  90  90  LYS   LYS B . n 
B 1 91  VAL   91  91  91  VAL   VAL B . n 
B 1 92  ASP   92  92  92  ASP   ASP B . n 
B 1 93  THR   93  93  93  THR   THR B . n 
B 1 94  ALA   94  94  94  ALA   ALA B . n 
B 1 95  ASN   95  95  95  ASN   ASN B . n 
B 1 96  PRO   96  96  96  PRO   PRO B . n 
B 1 97  LYS   97  97  97  LYS   LYS B . n 
B 1 98  THR   98  98  98  THR   THR B . n 
B 1 99  PRO   99  99  99  PRO   PRO B . n 
B 1 100 LYS   100 100 100 LYS   LYS B . n 
B 1 101 TYR   101 101 101 TYR   TYR B . n 
B 1 102 LYS   102 102 102 LYS   LYS B . n 
B 1 103 PHE   103 103 103 PHE   PHE B . n 
B 1 104 VAL   104 104 104 VAL   VAL B . n 
B 1 105 ARG   105 105 105 ARG   ARG B . n 
B 1 106 ILE   106 106 106 ILE   ILE B . n 
B 1 107 GLN   107 107 107 GLN   GLN B . n 
B 1 108 PRO   108 108 108 PRO   PRO B . n 
B 1 109 GLY   109 109 109 GLY   GLY B . n 
B 1 110 GLN   110 110 110 GLN   GLN B . n 
B 1 111 THR   111 111 111 THR   THR B . n 
B 1 112 PHE   112 112 112 PHE   PHE B . n 
B 1 113 SER   113 113 113 SER   SER B . n 
B 1 114 VAL   114 114 114 VAL   VAL B . n 
B 1 115 LEU   115 115 115 LEU   LEU B . n 
B 1 116 ALA   116 116 116 ALA   ALA B . n 
B 1 117 CYS   117 117 117 CYS   CYS B . n 
B 1 118 TYR   118 118 118 TYR   TYR B . n 
B 1 119 ASN   119 119 119 ASN   ASN B . n 
B 1 120 GLY   120 120 120 GLY   GLY B . n 
B 1 121 SER   121 121 121 SER   SER B . n 
B 1 122 PRO   122 122 122 PRO   PRO B . n 
B 1 123 SER   123 123 123 SER   SER B . n 
B 1 124 GLY   124 124 124 GLY   GLY B . n 
B 1 125 VAL   125 125 125 VAL   VAL B . n 
B 1 126 TYR   126 126 126 TYR   TYR B . n 
B 1 127 GLN   127 127 127 GLN   GLN B . n 
B 1 128 CYS   128 128 128 CYS   CYS B . n 
B 1 129 ALA   129 129 129 ALA   ALA B . n 
B 1 130 MET   130 130 130 MET   MET B . n 
B 1 131 ARG   131 131 131 ARG   ARG B . n 
B 1 132 PRO   132 132 132 PRO   PRO B . n 
B 1 133 ASN   133 133 133 ASN   ASN B . n 
B 1 134 PHE   134 134 134 PHE   PHE B . n 
B 1 135 THR   135 135 135 THR   THR B . n 
B 1 136 ILE   136 136 136 ILE   ILE B . n 
B 1 137 LYS   137 137 137 LYS   LYS B . n 
B 1 138 GLY   138 138 138 GLY   GLY B . n 
B 1 139 SER   139 139 139 SER   SER B . n 
B 1 140 PHE   140 140 140 PHE   PHE B . n 
B 1 141 LEU   141 141 141 LEU   LEU B . n 
B 1 142 ASN   142 142 142 ASN   ASN B . n 
B 1 143 GLY   143 143 143 GLY   GLY B . n 
B 1 144 SER   144 144 144 SER   SER B . n 
B 1 145 CYS   145 145 145 CYS   CYS B . n 
B 1 146 GLY   146 146 146 GLY   GLY B . n 
B 1 147 SER   147 147 147 SER   SER B . n 
B 1 148 VAL   148 148 148 VAL   VAL B . n 
B 1 149 GLY   149 149 149 GLY   GLY B . n 
B 1 150 PHE   150 150 150 PHE   PHE B . n 
B 1 151 ASN   151 151 151 ASN   ASN B . n 
B 1 152 ILE   152 152 152 ILE   ILE B . n 
B 1 153 ASP   153 153 153 ASP   ASP B . n 
B 1 154 TYR   154 154 154 TYR   TYR B . n 
B 1 155 ASP   155 155 155 ASP   ASP B . n 
B 1 156 CYS   156 156 156 CYS   CYS B . n 
B 1 157 VAL   157 157 157 VAL   VAL B . n 
B 1 158 SER   158 158 158 SER   SER B . n 
B 1 159 PHE   159 159 159 PHE   PHE B . n 
B 1 160 CYS   160 160 160 CYS   CYS B . n 
B 1 161 TYR   161 161 161 TYR   TYR B . n 
B 1 162 MET   162 162 162 MET   MET B . n 
B 1 163 HIS   163 163 163 HIS   HIS B . n 
B 1 164 HIS   164 164 164 HIS   HIS B . n 
B 1 165 MET   165 165 165 MET   MET B . n 
B 1 166 GLU   166 166 166 GLU   GLU B . n 
B 1 167 LEU   167 167 167 LEU   LEU B . n 
B 1 168 PRO   168 168 168 PRO   PRO B . n 
B 1 169 THR   169 169 169 THR   THR B . n 
B 1 170 GLY   170 170 170 GLY   GLY B . n 
B 1 171 VAL   171 171 171 VAL   VAL B . n 
B 1 172 HIS   172 172 172 HIS   HIS B . n 
B 1 173 ALA   173 173 173 ALA   ALA B . n 
B 1 174 GLY   174 174 174 GLY   GLY B . n 
B 1 175 THR   175 175 175 THR   THR B . n 
B 1 176 ASP   176 176 176 ASP   ASP B . n 
B 1 177 LEU   177 177 177 LEU   LEU B . n 
B 1 178 GLU   178 178 178 GLU   GLU B . n 
B 1 179 GLY   179 179 179 GLY   GLY B . n 
B 1 180 ASN   180 180 180 ASN   ASN B . n 
B 1 181 PHE   181 181 181 PHE   PHE B . n 
B 1 182 TYR   182 182 182 TYR   TYR B . n 
B 1 183 GLY   183 183 183 GLY   GLY B . n 
B 1 184 PRO   184 184 184 PRO   PRO B . n 
B 1 185 PHE   185 185 185 PHE   PHE B . n 
B 1 186 VAL   186 186 186 VAL   VAL B . n 
B 1 187 ASP   187 187 187 ASP   ASP B . n 
B 1 188 ARG   188 188 188 ARG   ARG B . n 
B 1 189 GLN   189 189 189 GLN   GLN B . n 
B 1 190 THR   190 190 190 THR   THR B . n 
B 1 191 ALA   191 191 191 ALA   ALA B . n 
B 1 192 GLN   192 192 192 GLN   GLN B . n 
B 1 193 ALA   193 193 193 ALA   ALA B . n 
B 1 194 ALA   194 194 194 ALA   ALA B . n 
B 1 195 GLY   195 195 195 GLY   GLY B . n 
B 1 196 THR   196 196 196 THR   THR B . n 
B 1 197 ASP   197 197 197 ASP   ASP B . n 
B 1 198 THR   198 198 198 THR   THR B . n 
B 1 199 THR   199 199 199 THR   THR B . n 
B 1 200 ILE   200 200 200 ILE   ILE B . n 
B 1 201 THR   201 201 201 THR   THR B . n 
B 1 202 VAL   202 202 202 VAL   VAL B . n 
B 1 203 ASN   203 203 203 ASN   ASN B . n 
B 1 204 VAL   204 204 204 VAL   VAL B . n 
B 1 205 LEU   205 205 205 LEU   LEU B . n 
B 1 206 ALA   206 206 206 ALA   ALA B . n 
B 1 207 TRP   207 207 207 TRP   TRP B . n 
B 1 208 LEU   208 208 208 LEU   LEU B . n 
B 1 209 TYR   209 209 209 TYR   TYR B . n 
B 1 210 ALA   210 210 210 ALA   ALA B . n 
B 1 211 ALA   211 211 211 ALA   ALA B . n 
B 1 212 VAL   212 212 212 VAL   VAL B . n 
B 1 213 ILE   213 213 213 ILE   ILE B . n 
B 1 214 ASN   214 214 214 ASN   ASN B . n 
B 1 215 GLY   215 215 215 GLY   GLY B . n 
B 1 216 ASP   216 216 216 ASP   ASP B . n 
B 1 217 ARG   217 217 217 ARG   ARG B . n 
B 1 218 TRP   218 218 218 TRP   TRP B . n 
B 1 219 PHE   219 219 219 PHE   PHE B . n 
B 1 220 LEU   220 220 220 LEU   LEU B . n 
B 1 221 ASN   221 221 221 ASN   ASN B . n 
B 1 222 ARG   222 222 222 ARG   ARG B . n 
B 1 223 PHE   223 223 223 PHE   ALA B . n 
B 1 224 THR   224 224 224 THR   THR B . n 
B 1 225 THR   225 225 225 THR   THR B . n 
B 1 226 THR   226 226 226 THR   THR B . n 
B 1 227 LEU   227 227 227 LEU   LEU B . n 
B 1 228 ASN   228 228 228 ASN   ASN B . n 
B 1 229 ASP   229 229 229 ASP   ASP B . n 
B 1 230 PHE   230 230 230 PHE   PHE B . n 
B 1 231 ASN   231 231 231 ASN   ASN B . n 
B 1 232 LEU   232 232 232 LEU   LEU B . n 
B 1 233 VAL   233 233 233 VAL   VAL B . n 
B 1 234 ALA   234 234 234 ALA   ALA B . n 
B 1 235 MET   235 235 235 MET   MET B . n 
B 1 236 LYS   236 236 236 LYS   LYS B . n 
B 1 237 TYR   237 237 237 TYR   TYR B . n 
B 1 238 ASN   238 238 238 ASN   ASN B . n 
B 1 239 TYR   239 239 239 TYR   TYR B . n 
B 1 240 GLU   240 240 240 GLU   GLU B . n 
B 1 241 PRO   241 241 241 PRO   PRO B . n 
B 1 242 LEU   242 242 242 LEU   LEU B . n 
B 1 243 THR   243 243 243 THR   THR B . n 
B 1 244 GLN   244 244 244 GLN   GLN B . n 
B 1 245 ASP   245 245 245 ASP   ASP B . n 
B 1 246 HIS   246 246 246 HIS   HIS B . n 
B 1 247 VAL   247 247 247 VAL   VAL B . n 
B 1 248 ASP   248 248 248 ASP   ASP B . n 
B 1 249 ILE   249 249 249 ILE   ILE B . n 
B 1 250 LEU   250 250 250 LEU   LEU B . n 
B 1 251 GLY   251 251 251 GLY   GLY B . n 
B 1 252 PRO   252 252 252 PRO   PRO B . n 
B 1 253 LEU   253 253 253 LEU   LEU B . n 
B 1 254 SER   254 254 254 SER   SER B . n 
B 1 255 ALA   255 255 255 ALA   ALA B . n 
B 1 256 GLN   256 256 256 GLN   GLN B . n 
B 1 257 THR   257 257 257 THR   THR B . n 
B 1 258 GLY   258 258 258 GLY   GLY B . n 
B 1 259 ILE   259 259 259 ILE   ILE B . n 
B 1 260 ALA   260 260 260 ALA   ALA B . n 
B 1 261 VAL   261 261 261 VAL   VAL B . n 
B 1 262 LEU   262 262 262 LEU   LEU B . n 
B 1 263 ASP   263 263 263 ASP   ASP B . n 
B 1 264 MET   264 264 264 MET   MET B . n 
B 1 265 CYS   265 265 265 CYS   CYS B . n 
B 1 266 ALA   266 266 266 ALA   ALA B . n 
B 1 267 SER   267 267 267 SER   SER B . n 
B 1 268 LEU   268 268 268 LEU   LEU B . n 
B 1 269 LYS   269 269 269 LYS   LYS B . n 
B 1 270 GLU   270 270 270 GLU   GLU B . n 
B 1 271 LEU   271 271 271 LEU   LEU B . n 
B 1 272 LEU   272 272 272 LEU   LEU B . n 
B 1 273 GLN   273 273 273 GLN   GLN B . n 
B 1 274 ASN   274 274 274 ASN   ASN B . n 
B 1 275 GLY   275 275 275 GLY   GLY B . n 
B 1 276 MET   276 276 276 MET   MET B . n 
B 1 277 ASN   277 277 277 ASN   ASN B . n 
B 1 278 GLY   278 278 278 GLY   GLY B . n 
B 1 279 ARG   279 279 279 ARG   ARG B . n 
B 1 280 THR   280 280 280 THR   THR B . n 
B 1 281 ILE   281 281 281 ILE   ILE B . n 
B 1 282 LEU   282 282 282 LEU   LEU B . n 
B 1 283 GLY   283 283 283 GLY   GLY B . n 
B 1 284 SER   284 284 284 SER   SER B . n 
B 1 285 ALA   285 285 285 ALA   ALA B . n 
B 1 286 LEU   286 286 286 LEU   LEU B . n 
B 1 287 LEU   287 287 287 LEU   LEU B . n 
B 1 288 GLU   288 288 288 GLU   GLU B . n 
B 1 289 ASP   289 289 289 ASP   ASP B . n 
B 1 290 GLU   290 290 290 GLU   GLU B . n 
B 1 291 PHE   291 291 291 PHE   PHE B . n 
B 1 292 THR   292 292 292 THR   THR B . n 
B 1 293 PRO   293 293 293 PRO   PRO B . n 
B 1 294 PHE   294 294 294 PHE   PHE B . n 
B 1 295 ASP   295 295 295 ASP   ASP B . n 
B 1 296 VAL   296 296 296 VAL   VAL B . n 
B 1 297 VAL   297 297 297 VAL   VAL B . n 
B 1 298 ARG   298 298 298 ARG   ARG B . n 
B 1 299 GLN   299 299 299 GLN   GLN B . n 
B 1 300 CYS   300 300 300 CYS   CYS B . n 
B 1 301 SER   301 301 301 SER   SER B . n 
B 1 302 GLY   302 302 302 GLY   GLY B . n 
B 1 303 VAL   303 303 ?   ?     ?   B . n 
B 1 304 THR   304 304 ?   ?     ?   B . n 
B 1 305 PHE   305 305 ?   ?     ?   B . n 
B 1 306 GLN   306 306 ?   ?     ?   B . n 
C 2 1   ACE   1   1   401 ACE   LIG C . n 
C 2 2   ABA   2   2   401 ABA   LIG C . n 
C 2 3   DTY   3   3   401 DTY   LIG C . n 
C 2 4   LEU   4   4   401 LEU   LIG C . n 
C 2 5   A1AMA 5   5   401 A1AMA LIG C . n 
D 2 1   ACE   1   1   401 ACE   LIG D . n 
D 2 2   ABA   2   2   401 ABA   LIG D . n 
D 2 3   DTY   3   3   401 DTY   LIG D . n 
D 2 4   LEU   4   4   401 LEU   LIG D . n 
D 2 5   A1AMA 5   5   401 A1AMA LIG D . n 
# 
loop_
_pdbx_entity_instance_feature.ordinal 
_pdbx_entity_instance_feature.comp_id 
_pdbx_entity_instance_feature.asym_id 
_pdbx_entity_instance_feature.seq_num 
_pdbx_entity_instance_feature.auth_comp_id 
_pdbx_entity_instance_feature.auth_asym_id 
_pdbx_entity_instance_feature.auth_seq_num 
_pdbx_entity_instance_feature.feature_type 
_pdbx_entity_instance_feature.details 
1 DTY   ? ? DTY   ? ? 'SUBJECT OF INVESTIGATION' ? 
2 ABA   ? ? ABA   ? ? 'SUBJECT OF INVESTIGATION' ? 
3 ACE   ? ? ACE   ? ? 'SUBJECT OF INVESTIGATION' ? 
4 A1AMA ? ? A1AMA ? ? 'SUBJECT OF INVESTIGATION' ? 
# 
loop_
_pdbx_nonpoly_scheme.asym_id 
_pdbx_nonpoly_scheme.entity_id 
_pdbx_nonpoly_scheme.mon_id 
_pdbx_nonpoly_scheme.ndb_seq_num 
_pdbx_nonpoly_scheme.pdb_seq_num 
_pdbx_nonpoly_scheme.auth_seq_num 
_pdbx_nonpoly_scheme.pdb_mon_id 
_pdbx_nonpoly_scheme.auth_mon_id 
_pdbx_nonpoly_scheme.pdb_strand_id 
_pdbx_nonpoly_scheme.pdb_ins_code 
E 3 HOH 1   401 322 HOH HOH A . 
E 3 HOH 2   402 117 HOH HOH A . 
E 3 HOH 3   403 239 HOH HOH A . 
E 3 HOH 4   404 327 HOH HOH A . 
E 3 HOH 5   405 371 HOH HOH A . 
E 3 HOH 6   406 196 HOH HOH A . 
E 3 HOH 7   407 362 HOH HOH A . 
E 3 HOH 8   408 135 HOH HOH A . 
E 3 HOH 9   409 277 HOH HOH A . 
E 3 HOH 10  410 280 HOH HOH A . 
E 3 HOH 11  411 323 HOH HOH A . 
E 3 HOH 12  412 88  HOH HOH A . 
E 3 HOH 13  413 301 HOH HOH A . 
E 3 HOH 14  414 295 HOH HOH A . 
E 3 HOH 15  415 336 HOH HOH A . 
E 3 HOH 16  416 300 HOH HOH A . 
E 3 HOH 17  417 76  HOH HOH A . 
E 3 HOH 18  418 160 HOH HOH A . 
E 3 HOH 19  419 141 HOH HOH A . 
E 3 HOH 20  420 17  HOH HOH A . 
E 3 HOH 21  421 248 HOH HOH A . 
E 3 HOH 22  422 129 HOH HOH A . 
E 3 HOH 23  423 164 HOH HOH A . 
E 3 HOH 24  424 90  HOH HOH A . 
E 3 HOH 25  425 161 HOH HOH A . 
E 3 HOH 26  426 240 HOH HOH A . 
E 3 HOH 27  427 42  HOH HOH A . 
E 3 HOH 28  428 34  HOH HOH A . 
E 3 HOH 29  429 218 HOH HOH A . 
E 3 HOH 30  430 337 HOH HOH A . 
E 3 HOH 31  431 221 HOH HOH A . 
E 3 HOH 32  432 206 HOH HOH A . 
E 3 HOH 33  433 33  HOH HOH A . 
E 3 HOH 34  434 108 HOH HOH A . 
E 3 HOH 35  435 85  HOH HOH A . 
E 3 HOH 36  436 105 HOH HOH A . 
E 3 HOH 37  437 169 HOH HOH A . 
E 3 HOH 38  438 43  HOH HOH A . 
E 3 HOH 39  439 38  HOH HOH A . 
E 3 HOH 40  440 19  HOH HOH A . 
E 3 HOH 41  441 325 HOH HOH A . 
E 3 HOH 42  442 46  HOH HOH A . 
E 3 HOH 43  443 205 HOH HOH A . 
E 3 HOH 44  444 55  HOH HOH A . 
E 3 HOH 45  445 178 HOH HOH A . 
E 3 HOH 46  446 73  HOH HOH A . 
E 3 HOH 47  447 335 HOH HOH A . 
E 3 HOH 48  448 156 HOH HOH A . 
E 3 HOH 49  449 15  HOH HOH A . 
E 3 HOH 50  450 44  HOH HOH A . 
E 3 HOH 51  451 87  HOH HOH A . 
E 3 HOH 52  452 64  HOH HOH A . 
E 3 HOH 53  453 53  HOH HOH A . 
E 3 HOH 54  454 188 HOH HOH A . 
E 3 HOH 55  455 304 HOH HOH A . 
E 3 HOH 56  456 143 HOH HOH A . 
E 3 HOH 57  457 89  HOH HOH A . 
E 3 HOH 58  458 45  HOH HOH A . 
E 3 HOH 59  459 146 HOH HOH A . 
E 3 HOH 60  460 91  HOH HOH A . 
E 3 HOH 61  461 136 HOH HOH A . 
E 3 HOH 62  462 168 HOH HOH A . 
E 3 HOH 63  463 321 HOH HOH A . 
E 3 HOH 64  464 57  HOH HOH A . 
E 3 HOH 65  465 228 HOH HOH A . 
E 3 HOH 66  466 93  HOH HOH A . 
E 3 HOH 67  467 3   HOH HOH A . 
E 3 HOH 68  468 63  HOH HOH A . 
E 3 HOH 69  469 214 HOH HOH A . 
E 3 HOH 70  470 100 HOH HOH A . 
E 3 HOH 71  471 215 HOH HOH A . 
E 3 HOH 72  472 80  HOH HOH A . 
E 3 HOH 73  473 65  HOH HOH A . 
E 3 HOH 74  474 30  HOH HOH A . 
E 3 HOH 75  475 41  HOH HOH A . 
E 3 HOH 76  476 40  HOH HOH A . 
E 3 HOH 77  477 150 HOH HOH A . 
E 3 HOH 78  478 287 HOH HOH A . 
E 3 HOH 79  479 84  HOH HOH A . 
E 3 HOH 80  480 201 HOH HOH A . 
E 3 HOH 81  481 260 HOH HOH A . 
E 3 HOH 82  482 28  HOH HOH A . 
E 3 HOH 83  483 242 HOH HOH A . 
E 3 HOH 84  484 173 HOH HOH A . 
E 3 HOH 85  485 5   HOH HOH A . 
E 3 HOH 86  486 92  HOH HOH A . 
E 3 HOH 87  487 137 HOH HOH A . 
E 3 HOH 88  488 9   HOH HOH A . 
E 3 HOH 89  489 39  HOH HOH A . 
E 3 HOH 90  490 282 HOH HOH A . 
E 3 HOH 91  491 230 HOH HOH A . 
E 3 HOH 92  492 203 HOH HOH A . 
E 3 HOH 93  493 263 HOH HOH A . 
E 3 HOH 94  494 18  HOH HOH A . 
E 3 HOH 95  495 113 HOH HOH A . 
E 3 HOH 96  496 162 HOH HOH A . 
E 3 HOH 97  497 291 HOH HOH A . 
E 3 HOH 98  498 202 HOH HOH A . 
E 3 HOH 99  499 10  HOH HOH A . 
E 3 HOH 100 500 184 HOH HOH A . 
E 3 HOH 101 501 1   HOH HOH A . 
E 3 HOH 102 502 237 HOH HOH A . 
E 3 HOH 103 503 258 HOH HOH A . 
E 3 HOH 104 504 54  HOH HOH A . 
E 3 HOH 105 505 209 HOH HOH A . 
E 3 HOH 106 506 154 HOH HOH A . 
E 3 HOH 107 507 95  HOH HOH A . 
E 3 HOH 108 508 167 HOH HOH A . 
E 3 HOH 109 509 172 HOH HOH A . 
E 3 HOH 110 510 12  HOH HOH A . 
E 3 HOH 111 511 118 HOH HOH A . 
E 3 HOH 112 512 122 HOH HOH A . 
E 3 HOH 113 513 70  HOH HOH A . 
E 3 HOH 114 514 197 HOH HOH A . 
E 3 HOH 115 515 349 HOH HOH A . 
E 3 HOH 116 516 220 HOH HOH A . 
E 3 HOH 117 517 94  HOH HOH A . 
E 3 HOH 118 518 102 HOH HOH A . 
E 3 HOH 119 519 29  HOH HOH A . 
E 3 HOH 120 520 204 HOH HOH A . 
E 3 HOH 121 521 81  HOH HOH A . 
E 3 HOH 122 522 339 HOH HOH A . 
E 3 HOH 123 523 245 HOH HOH A . 
E 3 HOH 124 524 191 HOH HOH A . 
E 3 HOH 125 525 26  HOH HOH A . 
E 3 HOH 126 526 133 HOH HOH A . 
E 3 HOH 127 527 79  HOH HOH A . 
E 3 HOH 128 528 36  HOH HOH A . 
E 3 HOH 129 529 158 HOH HOH A . 
E 3 HOH 130 530 101 HOH HOH A . 
E 3 HOH 131 531 149 HOH HOH A . 
E 3 HOH 132 532 199 HOH HOH A . 
E 3 HOH 133 533 170 HOH HOH A . 
E 3 HOH 134 534 316 HOH HOH A . 
E 3 HOH 135 535 338 HOH HOH A . 
E 3 HOH 136 536 366 HOH HOH A . 
E 3 HOH 137 537 266 HOH HOH A . 
E 3 HOH 138 538 66  HOH HOH A . 
E 3 HOH 139 539 211 HOH HOH A . 
E 3 HOH 140 540 235 HOH HOH A . 
E 3 HOH 141 541 152 HOH HOH A . 
E 3 HOH 142 542 77  HOH HOH A . 
E 3 HOH 143 543 27  HOH HOH A . 
E 3 HOH 144 544 293 HOH HOH A . 
E 3 HOH 145 545 320 HOH HOH A . 
E 3 HOH 146 546 312 HOH HOH A . 
E 3 HOH 147 547 326 HOH HOH A . 
E 3 HOH 148 548 51  HOH HOH A . 
E 3 HOH 149 549 341 HOH HOH A . 
E 3 HOH 150 550 317 HOH HOH A . 
E 3 HOH 151 551 126 HOH HOH A . 
E 3 HOH 152 552 241 HOH HOH A . 
E 3 HOH 153 553 272 HOH HOH A . 
E 3 HOH 154 554 306 HOH HOH A . 
E 3 HOH 155 555 352 HOH HOH A . 
E 3 HOH 156 556 243 HOH HOH A . 
E 3 HOH 157 557 329 HOH HOH A . 
E 3 HOH 158 558 219 HOH HOH A . 
E 3 HOH 159 559 250 HOH HOH A . 
E 3 HOH 160 560 308 HOH HOH A . 
E 3 HOH 161 561 318 HOH HOH A . 
E 3 HOH 162 562 144 HOH HOH A . 
E 3 HOH 163 563 299 HOH HOH A . 
E 3 HOH 164 564 264 HOH HOH A . 
E 3 HOH 165 565 180 HOH HOH A . 
E 3 HOH 166 566 232 HOH HOH A . 
E 3 HOH 167 567 307 HOH HOH A . 
E 3 HOH 168 568 177 HOH HOH A . 
E 3 HOH 169 569 310 HOH HOH A . 
E 3 HOH 170 570 120 HOH HOH A . 
E 3 HOH 171 571 311 HOH HOH A . 
E 3 HOH 172 572 351 HOH HOH A . 
E 3 HOH 173 573 363 HOH HOH A . 
E 3 HOH 174 574 251 HOH HOH A . 
E 3 HOH 175 575 185 HOH HOH A . 
E 3 HOH 176 576 273 HOH HOH A . 
E 3 HOH 177 577 233 HOH HOH A . 
E 3 HOH 178 578 139 HOH HOH A . 
E 3 HOH 179 579 350 HOH HOH A . 
E 3 HOH 180 580 367 HOH HOH A . 
E 3 HOH 181 581 368 HOH HOH A . 
E 3 HOH 182 582 148 HOH HOH A . 
E 3 HOH 183 583 257 HOH HOH A . 
E 3 HOH 184 584 98  HOH HOH A . 
E 3 HOH 185 585 275 HOH HOH A . 
E 3 HOH 186 586 110 HOH HOH A . 
E 3 HOH 187 587 319 HOH HOH A . 
E 3 HOH 188 588 364 HOH HOH A . 
E 3 HOH 189 589 244 HOH HOH A . 
E 3 HOH 190 590 342 HOH HOH A . 
E 3 HOH 191 591 225 HOH HOH A . 
E 3 HOH 192 592 246 HOH HOH A . 
E 3 HOH 193 593 315 HOH HOH A . 
E 3 HOH 194 594 186 HOH HOH A . 
E 3 HOH 195 595 372 HOH HOH A . 
E 3 HOH 196 596 210 HOH HOH A . 
E 3 HOH 197 597 360 HOH HOH A . 
E 3 HOH 198 598 274 HOH HOH A . 
F 3 HOH 1   401 365 HOH HOH B . 
F 3 HOH 2   402 147 HOH HOH B . 
F 3 HOH 3   403 47  HOH HOH B . 
F 3 HOH 4   404 114 HOH HOH B . 
F 3 HOH 5   405 99  HOH HOH B . 
F 3 HOH 6   406 265 HOH HOH B . 
F 3 HOH 7   407 357 HOH HOH B . 
F 3 HOH 8   408 324 HOH HOH B . 
F 3 HOH 9   409 249 HOH HOH B . 
F 3 HOH 10  410 68  HOH HOH B . 
F 3 HOH 11  411 175 HOH HOH B . 
F 3 HOH 12  412 153 HOH HOH B . 
F 3 HOH 13  413 97  HOH HOH B . 
F 3 HOH 14  414 255 HOH HOH B . 
F 3 HOH 15  415 49  HOH HOH B . 
F 3 HOH 16  416 288 HOH HOH B . 
F 3 HOH 17  417 348 HOH HOH B . 
F 3 HOH 18  418 20  HOH HOH B . 
F 3 HOH 19  419 75  HOH HOH B . 
F 3 HOH 20  420 109 HOH HOH B . 
F 3 HOH 21  421 346 HOH HOH B . 
F 3 HOH 22  422 151 HOH HOH B . 
F 3 HOH 23  423 130 HOH HOH B . 
F 3 HOH 24  424 25  HOH HOH B . 
F 3 HOH 25  425 286 HOH HOH B . 
F 3 HOH 26  426 181 HOH HOH B . 
F 3 HOH 27  427 131 HOH HOH B . 
F 3 HOH 28  428 328 HOH HOH B . 
F 3 HOH 29  429 56  HOH HOH B . 
F 3 HOH 30  430 112 HOH HOH B . 
F 3 HOH 31  431 48  HOH HOH B . 
F 3 HOH 32  432 171 HOH HOH B . 
F 3 HOH 33  433 271 HOH HOH B . 
F 3 HOH 34  434 116 HOH HOH B . 
F 3 HOH 35  435 124 HOH HOH B . 
F 3 HOH 36  436 14  HOH HOH B . 
F 3 HOH 37  437 195 HOH HOH B . 
F 3 HOH 38  438 103 HOH HOH B . 
F 3 HOH 39  439 193 HOH HOH B . 
F 3 HOH 40  440 35  HOH HOH B . 
F 3 HOH 41  441 82  HOH HOH B . 
F 3 HOH 42  442 7   HOH HOH B . 
F 3 HOH 43  443 145 HOH HOH B . 
F 3 HOH 44  444 200 HOH HOH B . 
F 3 HOH 45  445 189 HOH HOH B . 
F 3 HOH 46  446 16  HOH HOH B . 
F 3 HOH 47  447 359 HOH HOH B . 
F 3 HOH 48  448 2   HOH HOH B . 
F 3 HOH 49  449 6   HOH HOH B . 
F 3 HOH 50  450 267 HOH HOH B . 
F 3 HOH 51  451 125 HOH HOH B . 
F 3 HOH 52  452 128 HOH HOH B . 
F 3 HOH 53  453 207 HOH HOH B . 
F 3 HOH 54  454 24  HOH HOH B . 
F 3 HOH 55  455 23  HOH HOH B . 
F 3 HOH 56  456 369 HOH HOH B . 
F 3 HOH 57  457 270 HOH HOH B . 
F 3 HOH 58  458 314 HOH HOH B . 
F 3 HOH 59  459 345 HOH HOH B . 
F 3 HOH 60  460 4   HOH HOH B . 
F 3 HOH 61  461 11  HOH HOH B . 
F 3 HOH 62  462 21  HOH HOH B . 
F 3 HOH 63  463 32  HOH HOH B . 
F 3 HOH 64  464 194 HOH HOH B . 
F 3 HOH 65  465 96  HOH HOH B . 
F 3 HOH 66  466 166 HOH HOH B . 
F 3 HOH 67  467 132 HOH HOH B . 
F 3 HOH 68  468 222 HOH HOH B . 
F 3 HOH 69  469 74  HOH HOH B . 
F 3 HOH 70  470 86  HOH HOH B . 
F 3 HOH 71  471 303 HOH HOH B . 
F 3 HOH 72  472 234 HOH HOH B . 
F 3 HOH 73  473 332 HOH HOH B . 
F 3 HOH 74  474 296 HOH HOH B . 
F 3 HOH 75  475 123 HOH HOH B . 
F 3 HOH 76  476 224 HOH HOH B . 
F 3 HOH 77  477 361 HOH HOH B . 
F 3 HOH 78  478 182 HOH HOH B . 
F 3 HOH 79  479 22  HOH HOH B . 
F 3 HOH 80  480 140 HOH HOH B . 
F 3 HOH 81  481 13  HOH HOH B . 
F 3 HOH 82  482 72  HOH HOH B . 
F 3 HOH 83  483 37  HOH HOH B . 
F 3 HOH 84  484 61  HOH HOH B . 
F 3 HOH 85  485 115 HOH HOH B . 
F 3 HOH 86  486 31  HOH HOH B . 
F 3 HOH 87  487 355 HOH HOH B . 
F 3 HOH 88  488 347 HOH HOH B . 
F 3 HOH 89  489 297 HOH HOH B . 
F 3 HOH 90  490 208 HOH HOH B . 
F 3 HOH 91  491 58  HOH HOH B . 
F 3 HOH 92  492 165 HOH HOH B . 
F 3 HOH 93  493 358 HOH HOH B . 
F 3 HOH 94  494 50  HOH HOH B . 
F 3 HOH 95  495 142 HOH HOH B . 
F 3 HOH 96  496 313 HOH HOH B . 
F 3 HOH 97  497 69  HOH HOH B . 
F 3 HOH 98  498 278 HOH HOH B . 
F 3 HOH 99  499 104 HOH HOH B . 
F 3 HOH 100 500 119 HOH HOH B . 
F 3 HOH 101 501 176 HOH HOH B . 
F 3 HOH 102 502 138 HOH HOH B . 
F 3 HOH 103 503 187 HOH HOH B . 
F 3 HOH 104 504 155 HOH HOH B . 
F 3 HOH 105 505 292 HOH HOH B . 
F 3 HOH 106 506 231 HOH HOH B . 
F 3 HOH 107 507 8   HOH HOH B . 
F 3 HOH 108 508 83  HOH HOH B . 
F 3 HOH 109 509 163 HOH HOH B . 
F 3 HOH 110 510 302 HOH HOH B . 
F 3 HOH 111 511 179 HOH HOH B . 
F 3 HOH 112 512 60  HOH HOH B . 
F 3 HOH 113 513 121 HOH HOH B . 
F 3 HOH 114 514 106 HOH HOH B . 
F 3 HOH 115 515 67  HOH HOH B . 
F 3 HOH 116 516 62  HOH HOH B . 
F 3 HOH 117 517 285 HOH HOH B . 
F 3 HOH 118 518 59  HOH HOH B . 
F 3 HOH 119 519 283 HOH HOH B . 
F 3 HOH 120 520 290 HOH HOH B . 
F 3 HOH 121 521 298 HOH HOH B . 
F 3 HOH 122 522 134 HOH HOH B . 
F 3 HOH 123 523 127 HOH HOH B . 
F 3 HOH 124 524 279 HOH HOH B . 
F 3 HOH 125 525 217 HOH HOH B . 
F 3 HOH 126 526 78  HOH HOH B . 
F 3 HOH 127 527 261 HOH HOH B . 
F 3 HOH 128 528 198 HOH HOH B . 
F 3 HOH 129 529 334 HOH HOH B . 
F 3 HOH 130 530 289 HOH HOH B . 
F 3 HOH 131 531 183 HOH HOH B . 
F 3 HOH 132 532 340 HOH HOH B . 
F 3 HOH 133 533 356 HOH HOH B . 
F 3 HOH 134 534 71  HOH HOH B . 
F 3 HOH 135 535 344 HOH HOH B . 
F 3 HOH 136 536 227 HOH HOH B . 
F 3 HOH 137 537 284 HOH HOH B . 
F 3 HOH 138 538 331 HOH HOH B . 
F 3 HOH 139 539 370 HOH HOH B . 
F 3 HOH 140 540 229 HOH HOH B . 
F 3 HOH 141 541 212 HOH HOH B . 
F 3 HOH 142 542 213 HOH HOH B . 
F 3 HOH 143 543 157 HOH HOH B . 
F 3 HOH 144 544 174 HOH HOH B . 
F 3 HOH 145 545 226 HOH HOH B . 
F 3 HOH 146 546 192 HOH HOH B . 
F 3 HOH 147 547 305 HOH HOH B . 
F 3 HOH 148 548 52  HOH HOH B . 
F 3 HOH 149 549 107 HOH HOH B . 
F 3 HOH 150 550 190 HOH HOH B . 
F 3 HOH 151 551 254 HOH HOH B . 
F 3 HOH 152 552 159 HOH HOH B . 
F 3 HOH 153 553 353 HOH HOH B . 
F 3 HOH 154 554 268 HOH HOH B . 
F 3 HOH 155 555 223 HOH HOH B . 
F 3 HOH 156 556 238 HOH HOH B . 
F 3 HOH 157 557 253 HOH HOH B . 
F 3 HOH 158 558 343 HOH HOH B . 
F 3 HOH 159 559 309 HOH HOH B . 
F 3 HOH 160 560 259 HOH HOH B . 
F 3 HOH 161 561 373 HOH HOH B . 
F 3 HOH 162 562 354 HOH HOH B . 
F 3 HOH 163 563 247 HOH HOH B . 
F 3 HOH 164 564 330 HOH HOH B . 
F 3 HOH 165 565 281 HOH HOH B . 
F 3 HOH 166 566 252 HOH HOH B . 
F 3 HOH 167 567 333 HOH HOH B . 
F 3 HOH 168 568 216 HOH HOH B . 
F 3 HOH 169 569 262 HOH HOH B . 
G 3 HOH 1   101 236 HOH HOH C . 
G 3 HOH 2   102 269 HOH HOH C . 
G 3 HOH 3   103 276 HOH HOH C . 
H 3 HOH 1   101 111 HOH HOH D . 
H 3 HOH 2   102 294 HOH HOH D . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 A TYR 154 ? CG  ? A TYR 154 CG  
2  1 Y 1 A TYR 154 ? CD1 ? A TYR 154 CD1 
3  1 Y 1 A TYR 154 ? CD2 ? A TYR 154 CD2 
4  1 Y 1 A TYR 154 ? CE1 ? A TYR 154 CE1 
5  1 Y 1 A TYR 154 ? CE2 ? A TYR 154 CE2 
6  1 Y 1 A TYR 154 ? CZ  ? A TYR 154 CZ  
7  1 Y 1 A TYR 154 ? OH  ? A TYR 154 OH  
8  1 Y 1 A ARG 222 ? CG  ? A ARG 222 CG  
9  1 Y 1 A ARG 222 ? CD  ? A ARG 222 CD  
10 1 Y 1 A ARG 222 ? NE  ? A ARG 222 NE  
11 1 Y 1 A ARG 222 ? CZ  ? A ARG 222 CZ  
12 1 Y 1 A ARG 222 ? NH1 ? A ARG 222 NH1 
13 1 Y 1 A ARG 222 ? NH2 ? A ARG 222 NH2 
14 1 Y 1 A PHE 294 ? CG  ? A PHE 294 CG  
15 1 Y 1 A PHE 294 ? CD1 ? A PHE 294 CD1 
16 1 Y 1 A PHE 294 ? CD2 ? A PHE 294 CD2 
17 1 Y 1 A PHE 294 ? CE1 ? A PHE 294 CE1 
18 1 Y 1 A PHE 294 ? CE2 ? A PHE 294 CE2 
19 1 Y 1 A PHE 294 ? CZ  ? A PHE 294 CZ  
20 1 Y 1 B PHE 223 ? CG  ? B PHE 223 CG  
21 1 Y 1 B PHE 223 ? CD1 ? B PHE 223 CD1 
22 1 Y 1 B PHE 223 ? CD2 ? B PHE 223 CD2 
23 1 Y 1 B PHE 223 ? CE1 ? B PHE 223 CE1 
24 1 Y 1 B PHE 223 ? CE2 ? B PHE 223 CE2 
25 1 Y 1 B PHE 223 ? CZ  ? B PHE 223 CZ  
# 
loop_
_software.citation_id 
_software.classification 
_software.compiler_name 
_software.compiler_version 
_software.contact_author 
_software.contact_author_email 
_software.date 
_software.description 
_software.dependencies 
_software.hardware 
_software.language 
_software.location 
_software.mods 
_software.name 
_software.os 
_software.os_version 
_software.type 
_software.version 
_software.pdbx_ordinal 
? refinement       ? ? ? ? ? ? ? ? ? ? ? PHENIX  ? ? ? 1.21_5207 1 
? 'data reduction' ? ? ? ? ? ? ? ? ? ? ? XDS     ? ? ? .         2 
? 'data scaling'   ? ? ? ? ? ? ? ? ? ? ? Aimless ? ? ? .         3 
? phasing          ? ? ? ? ? ? ? ? ? ? ? PHASER  ? ? ? .         4 
# 
_cell.angle_alpha                  90.000 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   107.821 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.000 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9BC1 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     55.210 
_cell.length_a_esd                 ? 
_cell.length_b                     98.637 
_cell.length_b_esd                 ? 
_cell.length_c                     59.136 
_cell.length_c_esd                 ? 
_cell.volume                       306587.456 
_cell.volume_esd                   ? 
_cell.Z_PDB                        4 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9BC1 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                4 
_symmetry.space_group_name_Hall            'P 2yb' 
_symmetry.space_group_name_H-M             'P 1 21 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9BC1 
_exptl.crystals_number            1 
_exptl.details                    ? 
_exptl.method                     'X-RAY DIFFRACTION' 
_exptl.method_details             ? 
# 
_exptl_crystal.colour                       ? 
_exptl_crystal.density_diffrn               ? 
_exptl_crystal.density_Matthews             2.27 
_exptl_crystal.density_method               ? 
_exptl_crystal.density_percent_sol          45.86 
_exptl_crystal.description                  ? 
_exptl_crystal.F_000                        ? 
_exptl_crystal.id                           1 
_exptl_crystal.preparation                  ? 
_exptl_crystal.size_max                     ? 
_exptl_crystal.size_mid                     ? 
_exptl_crystal.size_min                     ? 
_exptl_crystal.size_rad                     ? 
_exptl_crystal.colour_lustre                ? 
_exptl_crystal.colour_modifier              ? 
_exptl_crystal.colour_primary               ? 
_exptl_crystal.density_meas                 ? 
_exptl_crystal.density_meas_esd             ? 
_exptl_crystal.density_meas_gt              ? 
_exptl_crystal.density_meas_lt              ? 
_exptl_crystal.density_meas_temp            ? 
_exptl_crystal.density_meas_temp_esd        ? 
_exptl_crystal.density_meas_temp_gt         ? 
_exptl_crystal.density_meas_temp_lt         ? 
_exptl_crystal.pdbx_crystal_image_url       ? 
_exptl_crystal.pdbx_crystal_image_format    ? 
_exptl_crystal.pdbx_mosaicity               ? 
_exptl_crystal.pdbx_mosaicity_esd           ? 
_exptl_crystal.pdbx_mosaic_method           ? 
_exptl_crystal.pdbx_mosaic_block_size       ? 
_exptl_crystal.pdbx_mosaic_block_size_esd   ? 
# 
_exptl_crystal_grow.apparatus       ? 
_exptl_crystal_grow.atmosphere      ? 
_exptl_crystal_grow.crystal_id      1 
_exptl_crystal_grow.details         ? 
_exptl_crystal_grow.method          'VAPOR DIFFUSION, SITTING DROP' 
_exptl_crystal_grow.method_ref      ? 
_exptl_crystal_grow.pH              6.5 
_exptl_crystal_grow.pressure        ? 
_exptl_crystal_grow.pressure_esd    ? 
_exptl_crystal_grow.seeding         ? 
_exptl_crystal_grow.seeding_ref     ? 
_exptl_crystal_grow.temp_details    ? 
_exptl_crystal_grow.temp_esd        ? 
_exptl_crystal_grow.time            ? 
_exptl_crystal_grow.pdbx_details    
'15%(w/v) PEG 3K, 20%(v/v) 1,2,4-butanetriol, 1%(w/v) NDSB 256, 0.5 mM of each Divalent cation II, 0.1 M MOPSO/bis-tris' 
_exptl_crystal_grow.pdbx_pH_range   ? 
_exptl_crystal_grow.temp            291.15 
# 
_diffrn.ambient_environment              ? 
_diffrn.ambient_temp                     100 
_diffrn.ambient_temp_details             ? 
_diffrn.ambient_temp_esd                 ? 
_diffrn.crystal_id                       1 
_diffrn.crystal_support                  ? 
_diffrn.crystal_treatment                ? 
_diffrn.details                          ? 
_diffrn.id                               1 
_diffrn.ambient_pressure                 ? 
_diffrn.ambient_pressure_esd             ? 
_diffrn.ambient_pressure_gt              ? 
_diffrn.ambient_pressure_lt              ? 
_diffrn.ambient_temp_gt                  ? 
_diffrn.ambient_temp_lt                  ? 
_diffrn.pdbx_serial_crystal_experiment   N 
# 
_diffrn_detector.details                      ? 
_diffrn_detector.detector                     PIXEL 
_diffrn_detector.diffrn_id                    1 
_diffrn_detector.type                         'DECTRIS EIGER X 16M' 
_diffrn_detector.area_resol_mean              ? 
_diffrn_detector.dtime                        ? 
_diffrn_detector.pdbx_frames_total            ? 
_diffrn_detector.pdbx_collection_time_total   ? 
_diffrn_detector.pdbx_collection_date         2021-10-10 
_diffrn_detector.pdbx_frequency               ? 
_diffrn_detector.id                           ? 
_diffrn_detector.number_of_axes               ? 
# 
_diffrn_radiation.collimation                      ? 
_diffrn_radiation.diffrn_id                        1 
_diffrn_radiation.filter_edge                      ? 
_diffrn_radiation.inhomogeneity                    ? 
_diffrn_radiation.monochromator                    ? 
_diffrn_radiation.polarisn_norm                    ? 
_diffrn_radiation.polarisn_ratio                   ? 
_diffrn_radiation.probe                            ? 
_diffrn_radiation.type                             ? 
_diffrn_radiation.xray_symbol                      ? 
_diffrn_radiation.wavelength_id                    1 
_diffrn_radiation.pdbx_monochromatic_or_laue_m_l   M 
_diffrn_radiation.pdbx_wavelength_list             ? 
_diffrn_radiation.pdbx_wavelength                  ? 
_diffrn_radiation.pdbx_diffrn_protocol             'SINGLE WAVELENGTH' 
_diffrn_radiation.pdbx_analyzer                    ? 
_diffrn_radiation.pdbx_scattering_type             x-ray 
# 
_diffrn_radiation_wavelength.id           1 
_diffrn_radiation_wavelength.wavelength   0.979 
_diffrn_radiation_wavelength.wt           1.0 
# 
_diffrn_source.current                     ? 
_diffrn_source.details                     ? 
_diffrn_source.diffrn_id                   1 
_diffrn_source.power                       ? 
_diffrn_source.size                        ? 
_diffrn_source.source                      SYNCHROTRON 
_diffrn_source.target                      ? 
_diffrn_source.type                        'APS BEAMLINE 21-ID-E' 
_diffrn_source.voltage                     ? 
_diffrn_source.take-off_angle              ? 
_diffrn_source.pdbx_wavelength_list        0.979 
_diffrn_source.pdbx_wavelength             ? 
_diffrn_source.pdbx_synchrotron_beamline   21-ID-E 
_diffrn_source.pdbx_synchrotron_site       APS 
# 
_reflns.B_iso_Wilson_estimate                          28.60 
_reflns.entry_id                                       9BC1 
_reflns.data_reduction_details                         ? 
_reflns.data_reduction_method                          ? 
_reflns.d_resolution_high                              1.72 
_reflns.d_resolution_low                               98.64 
_reflns.details                                        ? 
_reflns.limit_h_max                                    ? 
_reflns.limit_h_min                                    ? 
_reflns.limit_k_max                                    ? 
_reflns.limit_k_min                                    ? 
_reflns.limit_l_max                                    ? 
_reflns.limit_l_min                                    ? 
_reflns.number_all                                     ? 
_reflns.number_obs                                     63943 
_reflns.observed_criterion                             ? 
_reflns.observed_criterion_F_max                       ? 
_reflns.observed_criterion_F_min                       ? 
_reflns.observed_criterion_I_max                       ? 
_reflns.observed_criterion_I_min                       ? 
_reflns.observed_criterion_sigma_F                     ? 
_reflns.observed_criterion_sigma_I                     ? 
_reflns.percent_possible_obs                           99.7 
_reflns.R_free_details                                 ? 
_reflns.Rmerge_F_all                                   ? 
_reflns.Rmerge_F_obs                                   ? 
_reflns.Friedel_coverage                               ? 
_reflns.number_gt                                      ? 
_reflns.threshold_expression                           ? 
_reflns.pdbx_redundancy                                10.2 
_reflns.pdbx_netI_over_av_sigmaI                       ? 
_reflns.pdbx_netI_over_sigmaI                          25.8 
_reflns.pdbx_res_netI_over_av_sigmaI_2                 ? 
_reflns.pdbx_res_netI_over_sigmaI_2                    ? 
_reflns.pdbx_chi_squared                               ? 
_reflns.pdbx_scaling_rejects                           ? 
_reflns.pdbx_d_res_high_opt                            ? 
_reflns.pdbx_d_res_low_opt                             ? 
_reflns.pdbx_d_res_opt_method                          ? 
_reflns.phase_calculation_details                      ? 
_reflns.pdbx_Rrim_I_all                                ? 
_reflns.pdbx_Rpim_I_all                                0.021 
_reflns.pdbx_d_opt                                     ? 
_reflns.pdbx_number_measured_all                       ? 
_reflns.pdbx_diffrn_id                                 1 
_reflns.pdbx_ordinal                                   1 
_reflns.pdbx_CC_half                                   1 
_reflns.pdbx_CC_star                                   ? 
_reflns.pdbx_R_split                                   ? 
_reflns.pdbx_Rmerge_I_obs                              0.044 
_reflns.pdbx_Rmerge_I_all                              ? 
_reflns.pdbx_Rsym_value                                ? 
_reflns.pdbx_CC_split_method                           ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_1_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_2_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[1]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[2]   ? 
_reflns.pdbx_aniso_diffraction_limit_axis_3_ortho[3]   ? 
_reflns.pdbx_aniso_diffraction_limit_1                 ? 
_reflns.pdbx_aniso_diffraction_limit_2                 ? 
_reflns.pdbx_aniso_diffraction_limit_3                 ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_1_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_2_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[1]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[2]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvector_3_ortho[3]     ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_1               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_2               ? 
_reflns.pdbx_aniso_B_tensor_eigenvalue_3               ? 
_reflns.pdbx_orthogonalization_convention              ? 
_reflns.pdbx_percent_possible_ellipsoidal              ? 
_reflns.pdbx_percent_possible_spherical                ? 
_reflns.pdbx_percent_possible_ellipsoidal_anomalous    ? 
_reflns.pdbx_percent_possible_spherical_anomalous      ? 
_reflns.pdbx_redundancy_anomalous                      ? 
_reflns.pdbx_CC_half_anomalous                         ? 
_reflns.pdbx_absDiff_over_sigma_anomalous              ? 
_reflns.pdbx_percent_possible_anomalous                ? 
_reflns.pdbx_observed_signal_threshold                 ? 
_reflns.pdbx_signal_type                               ? 
_reflns.pdbx_signal_details                            ? 
_reflns.pdbx_signal_software_id                        ? 
# 
_reflns_shell.d_res_high                                    1.72 
_reflns_shell.d_res_low                                     1.75 
_reflns_shell.meanI_over_sigI_all                           ? 
_reflns_shell.meanI_over_sigI_obs                           2.7 
_reflns_shell.number_measured_all                           ? 
_reflns_shell.number_measured_obs                           ? 
_reflns_shell.number_possible                               ? 
_reflns_shell.number_unique_all                             ? 
_reflns_shell.number_unique_obs                             3287 
_reflns_shell.percent_possible_obs                          ? 
_reflns_shell.Rmerge_F_all                                  ? 
_reflns_shell.Rmerge_F_obs                                  ? 
_reflns_shell.meanI_over_sigI_gt                            ? 
_reflns_shell.meanI_over_uI_all                             ? 
_reflns_shell.meanI_over_uI_gt                              ? 
_reflns_shell.number_measured_gt                            ? 
_reflns_shell.number_unique_gt                              ? 
_reflns_shell.percent_possible_gt                           ? 
_reflns_shell.Rmerge_F_gt                                   ? 
_reflns_shell.Rmerge_I_gt                                   ? 
_reflns_shell.pdbx_redundancy                               ? 
_reflns_shell.pdbx_chi_squared                              ? 
_reflns_shell.pdbx_netI_over_sigmaI_all                     ? 
_reflns_shell.pdbx_netI_over_sigmaI_obs                     ? 
_reflns_shell.pdbx_Rrim_I_all                               ? 
_reflns_shell.pdbx_Rpim_I_all                               0.350 
_reflns_shell.pdbx_rejects                                  ? 
_reflns_shell.pdbx_ordinal                                  1 
_reflns_shell.pdbx_diffrn_id                                1 
_reflns_shell.pdbx_CC_half                                  0.877 
_reflns_shell.pdbx_CC_star                                  ? 
_reflns_shell.pdbx_R_split                                  ? 
_reflns_shell.percent_possible_all                          ? 
_reflns_shell.Rmerge_I_all                                  ? 
_reflns_shell.Rmerge_I_obs                                  0.714 
_reflns_shell.pdbx_Rsym_value                               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal             ? 
_reflns_shell.pdbx_percent_possible_spherical               ? 
_reflns_shell.pdbx_percent_possible_ellipsoidal_anomalous   ? 
_reflns_shell.pdbx_percent_possible_spherical_anomalous     ? 
_reflns_shell.pdbx_redundancy_anomalous                     ? 
_reflns_shell.pdbx_CC_half_anomalous                        ? 
_reflns_shell.pdbx_absDiff_over_sigma_anomalous             ? 
_reflns_shell.pdbx_percent_possible_anomalous               ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               33.75 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9BC1 
_refine.pdbx_refine_id                           'X-RAY DIFFRACTION' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            1.72 
_refine.ls_d_res_low                             56.30 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     63732 
_refine.ls_number_reflns_R_free                  2000 
_refine.ls_number_reflns_R_work                  61732 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    99.37 
_refine.ls_percent_reflns_R_free                 3.14 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          0.1836 
_refine.ls_R_factor_R_free                       0.1996 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       0.1831 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    'FLAT BULK SOLVENT MODEL' 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          1.35 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               'FREE R-VALUE' 
_refine.pdbx_method_to_determine_struct          'MOLECULAR REPLACEMENT' 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       'GeoStd + Monomer Library + CDL v1.2' 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             1.1000 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             0.9000 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 21.6906 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           1 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            0.2147 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
_refine_hist.pdbx_refine_id                   'X-RAY DIFFRACTION' 
_refine_hist.cycle_id                         LAST 
_refine_hist.details                          ? 
_refine_hist.d_res_high                       1.72 
_refine_hist.d_res_low                        56.30 
_refine_hist.number_atoms_solvent             372 
_refine_hist.number_atoms_total               5098 
_refine_hist.number_reflns_all                ? 
_refine_hist.number_reflns_obs                ? 
_refine_hist.number_reflns_R_free             ? 
_refine_hist.number_reflns_R_work             ? 
_refine_hist.R_factor_all                     ? 
_refine_hist.R_factor_obs                     ? 
_refine_hist.R_factor_R_free                  ? 
_refine_hist.R_factor_R_work                  ? 
_refine_hist.pdbx_number_residues_total       ? 
_refine_hist.pdbx_B_iso_mean_ligand           ? 
_refine_hist.pdbx_B_iso_mean_solvent          ? 
_refine_hist.pdbx_number_atoms_protein        4642 
_refine_hist.pdbx_number_atoms_nucleic_acid   0 
_refine_hist.pdbx_number_atoms_ligand         84 
_refine_hist.pdbx_number_atoms_lipid          ? 
_refine_hist.pdbx_number_atoms_carb           ? 
_refine_hist.pdbx_pseudo_atom_details         ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'X-RAY DIFFRACTION' ? 0.0086  ? 4831 ? f_bond_d           ? ? 
'X-RAY DIFFRACTION' ? 1.0405  ? 6569 ? f_angle_d          ? ? 
'X-RAY DIFFRACTION' ? 0.0601  ? 740  ? f_chiral_restr     ? ? 
'X-RAY DIFFRACTION' ? 0.0082  ? 853  ? f_plane_restr      ? ? 
'X-RAY DIFFRACTION' ? 14.5072 ? 1729 ? f_dihedral_angle_d ? ? 
# 
loop_
_refine_ls_shell.pdbx_refine_id 
_refine_ls_shell.d_res_high 
_refine_ls_shell.d_res_low 
_refine_ls_shell.number_reflns_all 
_refine_ls_shell.number_reflns_obs 
_refine_ls_shell.number_reflns_R_free 
_refine_ls_shell.number_reflns_R_work 
_refine_ls_shell.percent_reflns_obs 
_refine_ls_shell.percent_reflns_R_free 
_refine_ls_shell.R_factor_all 
_refine_ls_shell.R_factor_obs 
_refine_ls_shell.R_factor_R_free_error 
_refine_ls_shell.R_factor_R_work 
_refine_ls_shell.redundancy_reflns_all 
_refine_ls_shell.redundancy_reflns_obs 
_refine_ls_shell.wR_factor_all 
_refine_ls_shell.wR_factor_obs 
_refine_ls_shell.wR_factor_R_free 
_refine_ls_shell.wR_factor_R_work 
_refine_ls_shell.pdbx_R_complete 
_refine_ls_shell.pdbx_total_number_of_bins_used 
_refine_ls_shell.pdbx_phase_error 
_refine_ls_shell.pdbx_fsc_work 
_refine_ls_shell.pdbx_fsc_free 
_refine_ls_shell.R_factor_R_free 
'X-RAY DIFFRACTION' 1.72 1.76  . . 136 4277 97.01 . . . . 0.2762 . . . . . . . . . . . 0.2929 
'X-RAY DIFFRACTION' 1.76 1.81  . . 132 4383 98.80 . . . . 0.2353 . . . . . . . . . . . 0.2519 
'X-RAY DIFFRACTION' 1.81 1.86  . . 159 4352 98.64 . . . . 0.2139 . . . . . . . . . . . 0.2310 
'X-RAY DIFFRACTION' 1.86 1.92  . . 137 4412 99.19 . . . . 0.2110 . . . . . . . . . . . 0.2496 
'X-RAY DIFFRACTION' 1.92 1.99  . . 139 4369 99.49 . . . . 0.2007 . . . . . . . . . . . 0.2308 
'X-RAY DIFFRACTION' 1.99 2.07  . . 149 4403 99.61 . . . . 0.2058 . . . . . . . . . . . 0.2365 
'X-RAY DIFFRACTION' 2.07 2.16  . . 140 4427 99.83 . . . . 0.2006 . . . . . . . . . . . 0.2158 
'X-RAY DIFFRACTION' 2.16 2.28  . . 142 4428 99.87 . . . . 0.1950 . . . . . . . . . . . 0.1926 
'X-RAY DIFFRACTION' 2.28 2.42  . . 146 4427 99.83 . . . . 0.2009 . . . . . . . . . . . 0.2350 
'X-RAY DIFFRACTION' 2.42 2.61  . . 148 4420 99.74 . . . . 0.1989 . . . . . . . . . . . 0.2270 
'X-RAY DIFFRACTION' 2.61 2.87  . . 140 4421 99.59 . . . . 0.2027 . . . . . . . . . . . 0.2228 
'X-RAY DIFFRACTION' 2.87 3.29  . . 145 4454 99.87 . . . . 0.1884 . . . . . . . . . . . 0.2108 
'X-RAY DIFFRACTION' 3.29 4.14  . . 138 4441 99.85 . . . . 0.1661 . . . . . . . . . . . 0.1676 
'X-RAY DIFFRACTION' 4.14 56.30 . . 149 4518 99.85 . . . . 0.1540 . . . . . . . . . . . 0.1685 
# 
_struct.entry_id                     9BC1 
_struct.title                        'SARS-CoV-2 Mpro in complex with peptide mimetic inhibitor' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9BC1 
_struct_keywords.text            'Protease, Inhibitor, VIRAL PROTEIN' 
_struct_keywords.pdbx_keywords   'VIRAL PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 1 ? 
C N N 2 ? 
D N N 2 ? 
E N N 3 ? 
F N N 3 ? 
G N N 3 ? 
H N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 UNP R1AB_SARS2 P0DTD1 ? 1 
;SGFRKMAFPSGKVEGCMVQVTCGTTTLNGLWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGH
SMQNCVLKLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSCGSVGFNIDYDCVSFC
YMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVNVLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYE
PLTQDHVDILGPLSAQTGIAVLDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQ
;
3264 
2 PDB 9BC1       9BC1   ? 2 ? 1    
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9BC1 A 1 ? 306 ? P0DTD1 3264 ? 3569 ? 1 306 
2 1 9BC1 B 1 ? 306 ? P0DTD1 3264 ? 3569 ? 1 306 
3 2 9BC1 C 1 ? 5   ? 9BC1   1    ? 5    ? 1 5   
4 2 9BC1 D 1 ? 5   ? 9BC1   1    ? 5    ? 1 5   
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       PISA 
_pdbx_struct_assembly.oligomeric_details   tetrameric 
_pdbx_struct_assembly.oligomeric_count     4 
# 
loop_
_pdbx_struct_assembly_prop.biol_id 
_pdbx_struct_assembly_prop.type 
_pdbx_struct_assembly_prop.value 
_pdbx_struct_assembly_prop.details 
1 'ABSA (A^2)' 5080  ? 
1 MORE         -27   ? 
1 'SSA (A^2)'  25160 ? 
# 
loop_
_pdbx_struct_assembly_gen.assembly_id 
_pdbx_struct_assembly_gen.oper_expression 
_pdbx_struct_assembly_gen.asym_id_list 
1 1 A,C,E,G 
1 2 B,D,F,H 
# 
loop_
_pdbx_struct_oper_list.id 
_pdbx_struct_oper_list.type 
_pdbx_struct_oper_list.name 
_pdbx_struct_oper_list.symmetry_operation 
_pdbx_struct_oper_list.matrix[1][1] 
_pdbx_struct_oper_list.matrix[1][2] 
_pdbx_struct_oper_list.matrix[1][3] 
_pdbx_struct_oper_list.vector[1] 
_pdbx_struct_oper_list.matrix[2][1] 
_pdbx_struct_oper_list.matrix[2][2] 
_pdbx_struct_oper_list.matrix[2][3] 
_pdbx_struct_oper_list.vector[2] 
_pdbx_struct_oper_list.matrix[3][1] 
_pdbx_struct_oper_list.matrix[3][2] 
_pdbx_struct_oper_list.matrix[3][3] 
_pdbx_struct_oper_list.vector[3] 
1 'identity operation'         1_555 x,y,z   1.0000000000 0.0000000000 0.0000000000 0.0000000000   0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
2 'crystal symmetry operation' 1_455 x-1,y,z 1.0000000000 0.0000000000 0.0000000000 -55.2100000000 0.0000000000 1.0000000000 
0.0000000000 0.0000000000 0.0000000000 0.0000000000 1.0000000000 0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 SER A 10  ? GLY A 15  ? SER A 10  GLY A 15  1 ? 6  
HELX_P HELX_P2  AA2 HIS A 41  ? CYS A 44  ? HIS A 41  CYS A 44  5 ? 4  
HELX_P HELX_P3  AA3 GLU A 47  ? ASN A 51  ? GLU A 47  ASN A 51  5 ? 5  
HELX_P HELX_P4  AA4 ASN A 53  ? ARG A 60  ? ASN A 53  ARG A 60  1 ? 8  
HELX_P HELX_P5  AA5 SER A 62  ? PHE A 66  ? SER A 62  PHE A 66  5 ? 5  
HELX_P HELX_P6  AA6 ILE A 200 ? ASN A 214 ? ILE A 200 ASN A 214 1 ? 15 
HELX_P HELX_P7  AA7 THR A 226 ? TYR A 237 ? THR A 226 TYR A 237 1 ? 12 
HELX_P HELX_P8  AA8 THR A 243 ? LEU A 250 ? THR A 243 LEU A 250 1 ? 8  
HELX_P HELX_P9  AA9 LEU A 250 ? GLY A 258 ? LEU A 250 GLY A 258 1 ? 9  
HELX_P HELX_P10 AB1 ALA A 260 ? GLY A 275 ? ALA A 260 GLY A 275 1 ? 16 
HELX_P HELX_P11 AB2 THR A 292 ? GLY A 302 ? THR A 292 GLY A 302 1 ? 11 
HELX_P HELX_P12 AB3 SER B 10  ? GLY B 15  ? SER B 10  GLY B 15  1 ? 6  
HELX_P HELX_P13 AB4 HIS B 41  ? CYS B 44  ? HIS B 41  CYS B 44  5 ? 4  
HELX_P HELX_P14 AB5 GLU B 47  ? ASN B 51  ? GLU B 47  ASN B 51  5 ? 5  
HELX_P HELX_P15 AB6 ASN B 53  ? ARG B 60  ? ASN B 53  ARG B 60  1 ? 8  
HELX_P HELX_P16 AB7 SER B 62  ? HIS B 64  ? SER B 62  HIS B 64  5 ? 3  
HELX_P HELX_P17 AB8 ILE B 200 ? ASN B 214 ? ILE B 200 ASN B 214 1 ? 15 
HELX_P HELX_P18 AB9 THR B 226 ? TYR B 237 ? THR B 226 TYR B 237 1 ? 12 
HELX_P HELX_P19 AC1 THR B 243 ? LEU B 250 ? THR B 243 LEU B 250 1 ? 8  
HELX_P HELX_P20 AC2 LEU B 250 ? GLY B 258 ? LEU B 250 GLY B 258 1 ? 9  
HELX_P HELX_P21 AC3 ALA B 260 ? GLY B 275 ? ALA B 260 GLY B 275 1 ? 16 
HELX_P HELX_P22 AC4 THR B 292 ? SER B 301 ? THR B 292 SER B 301 1 ? 10 
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
covale1 covale none ? B CYS 145 SG ? ? ? 1_555 D A1AMA 5 C36 ? ? B CYS 145 D A1AMA 5 1_555 ? ? ? ? ? ? ? 1.764 ? ? 
covale2 covale both ? C ACE 1   C  ? ? ? 1_555 C ABA   2 N   ? ? C ACE 1   C ABA   2 1_555 ? ? ? ? ? ? ? 1.434 ? ? 
covale3 covale both ? C ABA 2   C  ? ? ? 1_555 C DTY   3 N   ? ? C ABA 2   C DTY   3 1_555 ? ? ? ? ? ? ? 1.431 ? ? 
covale4 covale both ? C DTY 3   C  ? ? ? 1_555 C LEU   4 N   ? ? C DTY 3   C LEU   4 1_555 ? ? ? ? ? ? ? 1.437 ? ? 
covale5 covale both ? C LEU 4   C  ? ? ? 1_555 C A1AMA 5 N29 ? ? C LEU 4   C A1AMA 5 1_555 ? ? ? ? ? ? ? 1.435 ? ? 
covale6 covale both ? D ACE 1   C  ? ? ? 1_555 D ABA   2 N   ? ? D ACE 1   D ABA   2 1_555 ? ? ? ? ? ? ? 1.447 ? ? 
covale7 covale both ? D ABA 2   C  ? ? ? 1_555 D DTY   3 N   ? ? D ABA 2   D DTY   3 1_555 ? ? ? ? ? ? ? 1.448 ? ? 
covale8 covale both ? D DTY 3   C  ? ? ? 1_555 D LEU   4 N   ? ? D DTY 3   D LEU   4 1_555 ? ? ? ? ? ? ? 1.433 ? ? 
covale9 covale both ? D LEU 4   C  ? ? ? 1_555 D A1AMA 5 N29 ? ? D LEU 4   D A1AMA 5 1_555 ? ? ? ? ? ? ? 1.441 ? ? 
# 
_struct_conn_type.id          covale 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 ABA   C 2   ? .     . . . ABA   C 2   ? 1_555 .     . . . .     .  .   ?   1  ABA   None 'Non-standard residue' 
2 A1AMA C 5   ? .     . . . A1AMA C 5   ? 1_555 .     . . . .     .  .   ?   1  A1AMA None 'Non-standard residue' 
3 ABA   D 2   ? .     . . . ABA   D 2   ? 1_555 .     . . . .     .  .   ?   1  ABA   None 'Non-standard residue' 
4 A1AMA D 5   ? .     . . . A1AMA D 5   ? 1_555 .     . . . .     .  .   ?   1  A1AMA None 'Non-standard residue' 
5 ACE   C 1   ? ABA   C 2 ? ACE   C 1   ? 1_555 ABA   C 2 ? 1_555 .  .   ABA 42 ACE   None 'Terminal acetylation' 
6 ACE   D 1   ? ABA   D 2 ? ACE   D 1   ? 1_555 ABA   D 2 ? 1_555 .  .   ABA 42 ACE   None 'Terminal acetylation' 
7 CYS   B 145 ? A1AMA D 5 ? CYS   B 145 ? 1_555 A1AMA D 5 ? 1_555 SG C36 .   .  .     None 'Non-standard linkage' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 7 ? 
AA2 ? 5 ? 
AA3 ? 3 ? 
AA4 ? 7 ? 
AA5 ? 5 ? 
AA6 ? 3 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA1 4 5 ? anti-parallel 
AA1 5 6 ? anti-parallel 
AA1 6 7 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA4 1 2 ? anti-parallel 
AA4 2 3 ? anti-parallel 
AA4 3 4 ? anti-parallel 
AA4 4 5 ? anti-parallel 
AA4 5 6 ? anti-parallel 
AA4 6 7 ? anti-parallel 
AA5 1 2 ? parallel      
AA5 2 3 ? anti-parallel 
AA5 3 4 ? anti-parallel 
AA5 4 5 ? anti-parallel 
AA6 1 2 ? parallel      
AA6 2 3 ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 VAL A 73  ? LEU A 75  ? VAL A 73  LEU A 75  
AA1 2 LEU A 67  ? ALA A 70  ? LEU A 67  ALA A 70  
AA1 3 MET A 17  ? CYS A 22  ? MET A 17  CYS A 22  
AA1 4 THR A 25  ? LEU A 32  ? THR A 25  LEU A 32  
AA1 5 VAL A 35  ? PRO A 39  ? VAL A 35  PRO A 39  
AA1 6 VAL A 86  ? VAL A 91  ? VAL A 86  VAL A 91  
AA1 7 VAL A 77  ? GLN A 83  ? VAL A 77  GLN A 83  
AA2 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA2 2 CYS A 156 ? GLU A 166 ? CYS A 156 GLU A 166 
AA2 3 VAL A 148 ? ASP A 153 ? VAL A 148 ASP A 153 
AA2 4 THR A 111 ? TYR A 118 ? THR A 111 TYR A 118 
AA2 5 SER A 121 ? ALA A 129 ? SER A 121 ALA A 129 
AA3 1 LYS A 100 ? PHE A 103 ? LYS A 100 PHE A 103 
AA3 2 CYS A 156 ? GLU A 166 ? CYS A 156 GLU A 166 
AA3 3 HIS A 172 ? THR A 175 ? HIS A 172 THR A 175 
AA4 1 VAL B 73  ? LEU B 75  ? VAL B 73  LEU B 75  
AA4 2 PHE B 66  ? ALA B 70  ? PHE B 66  ALA B 70  
AA4 3 MET B 17  ? CYS B 22  ? MET B 17  CYS B 22  
AA4 4 THR B 25  ? LEU B 32  ? THR B 25  LEU B 32  
AA4 5 VAL B 35  ? PRO B 39  ? VAL B 35  PRO B 39  
AA4 6 VAL B 86  ? VAL B 91  ? VAL B 86  VAL B 91  
AA4 7 VAL B 77  ? GLN B 83  ? VAL B 77  GLN B 83  
AA5 1 LYS B 100 ? PHE B 103 ? LYS B 100 PHE B 103 
AA5 2 CYS B 156 ? GLU B 166 ? CYS B 156 GLU B 166 
AA5 3 VAL B 148 ? ASP B 153 ? VAL B 148 ASP B 153 
AA5 4 THR B 111 ? TYR B 118 ? THR B 111 TYR B 118 
AA5 5 SER B 121 ? ALA B 129 ? SER B 121 ALA B 129 
AA6 1 LYS B 100 ? PHE B 103 ? LYS B 100 PHE B 103 
AA6 2 CYS B 156 ? GLU B 166 ? CYS B 156 GLU B 166 
AA6 3 HIS B 172 ? THR B 175 ? HIS B 172 THR B 175 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 O LEU A 75  ? O LEU A 75  N VAL A 68  ? N VAL A 68  
AA1 2 3 O GLN A 69  ? O GLN A 69  N GLN A 19  ? N GLN A 19  
AA1 3 4 N VAL A 20  ? N VAL A 20  O LEU A 27  ? O LEU A 27  
AA1 4 5 N LEU A 30  ? N LEU A 30  O TYR A 37  ? O TYR A 37  
AA1 5 6 N CYS A 38  ? N CYS A 38  O LEU A 87  ? O LEU A 87  
AA1 6 7 O LYS A 90  ? O LYS A 90  N ILE A 78  ? N ILE A 78  
AA2 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA2 2 3 O SER A 158 ? O SER A 158 N ASN A 151 ? N ASN A 151 
AA2 3 4 O PHE A 150 ? O PHE A 150 N SER A 113 ? N SER A 113 
AA2 4 5 N ALA A 116 ? N ALA A 116 O SER A 123 ? O SER A 123 
AA3 1 2 N LYS A 100 ? N LYS A 100 O VAL A 157 ? O VAL A 157 
AA3 2 3 N MET A 165 ? N MET A 165 O ALA A 173 ? O ALA A 173 
AA4 1 2 O VAL B 73  ? O VAL B 73  N ALA B 70  ? N ALA B 70  
AA4 2 3 O GLN B 69  ? O GLN B 69  N GLN B 19  ? N GLN B 19  
AA4 3 4 N VAL B 20  ? N VAL B 20  O LEU B 27  ? O LEU B 27  
AA4 4 5 N LEU B 32  ? N LEU B 32  O VAL B 35  ? O VAL B 35  
AA4 5 6 N CYS B 38  ? N CYS B 38  O LEU B 87  ? O LEU B 87  
AA4 6 7 O VAL B 86  ? O VAL B 86  N GLN B 83  ? N GLN B 83  
AA5 1 2 N LYS B 100 ? N LYS B 100 O VAL B 157 ? O VAL B 157 
AA5 2 3 O SER B 158 ? O SER B 158 N ASN B 151 ? N ASN B 151 
AA5 3 4 O PHE B 150 ? O PHE B 150 N SER B 113 ? N SER B 113 
AA5 4 5 N ALA B 116 ? N ALA B 116 O SER B 123 ? O SER B 123 
AA6 1 2 N LYS B 100 ? N LYS B 100 O VAL B 157 ? O VAL B 157 
AA6 2 3 N MET B 165 ? N MET B 165 O ALA B 173 ? O ALA B 173 
# 
_pdbx_entry_details.entry_id                   9BC1 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_close_contact.id 
_pdbx_validate_close_contact.PDB_model_num 
_pdbx_validate_close_contact.auth_atom_id_1 
_pdbx_validate_close_contact.auth_asym_id_1 
_pdbx_validate_close_contact.auth_comp_id_1 
_pdbx_validate_close_contact.auth_seq_id_1 
_pdbx_validate_close_contact.PDB_ins_code_1 
_pdbx_validate_close_contact.label_alt_id_1 
_pdbx_validate_close_contact.auth_atom_id_2 
_pdbx_validate_close_contact.auth_asym_id_2 
_pdbx_validate_close_contact.auth_comp_id_2 
_pdbx_validate_close_contact.auth_seq_id_2 
_pdbx_validate_close_contact.PDB_ins_code_2 
_pdbx_validate_close_contact.label_alt_id_2 
_pdbx_validate_close_contact.dist 
1 1 OD2 A ASP 248 ? ? O A HOH 401 ? ? 1.92 
2 1 OD1 B ASP 248 ? ? O B HOH 401 ? ? 2.16 
3 1 NH1 B ARG 298 ? ? O B HOH 402 ? ? 2.18 
# 
loop_
_pdbx_validate_symm_contact.id 
_pdbx_validate_symm_contact.PDB_model_num 
_pdbx_validate_symm_contact.auth_atom_id_1 
_pdbx_validate_symm_contact.auth_asym_id_1 
_pdbx_validate_symm_contact.auth_comp_id_1 
_pdbx_validate_symm_contact.auth_seq_id_1 
_pdbx_validate_symm_contact.PDB_ins_code_1 
_pdbx_validate_symm_contact.label_alt_id_1 
_pdbx_validate_symm_contact.site_symmetry_1 
_pdbx_validate_symm_contact.auth_atom_id_2 
_pdbx_validate_symm_contact.auth_asym_id_2 
_pdbx_validate_symm_contact.auth_comp_id_2 
_pdbx_validate_symm_contact.auth_seq_id_2 
_pdbx_validate_symm_contact.PDB_ins_code_2 
_pdbx_validate_symm_contact.label_alt_id_2 
_pdbx_validate_symm_contact.site_symmetry_2 
_pdbx_validate_symm_contact.dist 
1 1 NH1 A ARG 4   ? ? 1_555 O B GLN 127 ? ? 1_455 2.16 
2 1 O   A HOH 577 ? ? 1_555 O B HOH 503 ? ? 1_455 2.18 
# 
_pdbx_validate_rmsd_bond.id                        1 
_pdbx_validate_rmsd_bond.PDB_model_num             1 
_pdbx_validate_rmsd_bond.auth_atom_id_1            CB 
_pdbx_validate_rmsd_bond.auth_asym_id_1            A 
_pdbx_validate_rmsd_bond.auth_comp_id_1            CYS 
_pdbx_validate_rmsd_bond.auth_seq_id_1             22 
_pdbx_validate_rmsd_bond.PDB_ins_code_1            ? 
_pdbx_validate_rmsd_bond.label_alt_id_1            B 
_pdbx_validate_rmsd_bond.auth_atom_id_2            SG 
_pdbx_validate_rmsd_bond.auth_asym_id_2            A 
_pdbx_validate_rmsd_bond.auth_comp_id_2            CYS 
_pdbx_validate_rmsd_bond.auth_seq_id_2             22 
_pdbx_validate_rmsd_bond.PDB_ins_code_2            ? 
_pdbx_validate_rmsd_bond.label_alt_id_2            B 
_pdbx_validate_rmsd_bond.bond_value                1.708 
_pdbx_validate_rmsd_bond.bond_target_value         1.812 
_pdbx_validate_rmsd_bond.bond_deviation            -0.104 
_pdbx_validate_rmsd_bond.bond_standard_deviation   0.016 
_pdbx_validate_rmsd_bond.linker_flag               N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 ASP A 33  ? ? 53.53   -127.70 
2 1 ASN A 51  ? ? -155.90 68.75   
3 1 ASN A 84  ? ? 57.46   -123.98 
4 1 TYR A 154 ? ? 57.48   -107.95 
5 1 ASP B 33  ? ? 50.65   -126.92 
6 1 ASN B 51  ? ? -153.09 75.00   
7 1 ASN B 84  ? ? 50.84   -122.31 
8 1 TYR B 154 ? ? 54.91   -106.94 
9 1 PRO B 184 ? ? -87.39  36.47   
# 
loop_
_space_group_symop.id 
_space_group_symop.operation_xyz 
1 x,y,z       
2 -x,y+1/2,-z 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1 1 Y 1 A SER 1   ? A SER 1   
2 1 Y 1 A THR 304 ? A THR 304 
3 1 Y 1 A PHE 305 ? A PHE 305 
4 1 Y 1 A GLN 306 ? A GLN 306 
5 1 Y 1 B VAL 303 ? B VAL 303 
6 1 Y 1 B THR 304 ? B THR 304 
7 1 Y 1 B PHE 305 ? B PHE 305 
8 1 Y 1 B GLN 306 ? B GLN 306 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AMA C30  C N S 1   
A1AMA C31  C N N 2   
A1AMA C32  C N N 3   
A1AMA C33  C N N 4   
A1AMA C36  C N N 5   
A1AMA C37  C N N 6   
A1AMA C39  C N N 7   
A1AMA N29  N N N 8   
A1AMA N34  N N N 9   
A1AMA O35  O N N 10  
A1AMA O40  O N N 11  
A1AMA O41  O N N 12  
A1AMA S38  S N N 13  
A1AMA H1   H N N 14  
A1AMA H2   H N N 15  
A1AMA H3   H N N 16  
A1AMA H4   H N N 17  
A1AMA H5   H N N 18  
A1AMA H6   H N N 19  
A1AMA H7   H N N 20  
A1AMA H8   H N N 21  
A1AMA H9   H N N 22  
A1AMA H10  H N N 23  
A1AMA H11  H N N 24  
A1AMA H12  H N N 25  
A1AMA H13  H N N 26  
A1AMA H14  H N N 27  
A1AMA H16  H N N 28  
A1AMA H17  H N N 29  
ABA   N    N N N 30  
ABA   CA   C N S 31  
ABA   C    C N N 32  
ABA   O    O N N 33  
ABA   CB   C N N 34  
ABA   CG   C N N 35  
ABA   OXT  O N N 36  
ABA   H    H N N 37  
ABA   H2   H N N 38  
ABA   HA   H N N 39  
ABA   HB3  H N N 40  
ABA   HB2  H N N 41  
ABA   HG1  H N N 42  
ABA   HG3  H N N 43  
ABA   HG2  H N N 44  
ABA   HXT  H N N 45  
ACE   C    C N N 46  
ACE   O    O N N 47  
ACE   CH3  C N N 48  
ACE   H    H N N 49  
ACE   H1   H N N 50  
ACE   H2   H N N 51  
ACE   H3   H N N 52  
ALA   N    N N N 53  
ALA   CA   C N S 54  
ALA   C    C N N 55  
ALA   O    O N N 56  
ALA   CB   C N N 57  
ALA   OXT  O N N 58  
ALA   H    H N N 59  
ALA   H2   H N N 60  
ALA   HA   H N N 61  
ALA   HB1  H N N 62  
ALA   HB2  H N N 63  
ALA   HB3  H N N 64  
ALA   HXT  H N N 65  
ARG   N    N N N 66  
ARG   CA   C N S 67  
ARG   C    C N N 68  
ARG   O    O N N 69  
ARG   CB   C N N 70  
ARG   CG   C N N 71  
ARG   CD   C N N 72  
ARG   NE   N N N 73  
ARG   CZ   C N N 74  
ARG   NH1  N N N 75  
ARG   NH2  N N N 76  
ARG   OXT  O N N 77  
ARG   H    H N N 78  
ARG   H2   H N N 79  
ARG   HA   H N N 80  
ARG   HB2  H N N 81  
ARG   HB3  H N N 82  
ARG   HG2  H N N 83  
ARG   HG3  H N N 84  
ARG   HD2  H N N 85  
ARG   HD3  H N N 86  
ARG   HE   H N N 87  
ARG   HH11 H N N 88  
ARG   HH12 H N N 89  
ARG   HH21 H N N 90  
ARG   HH22 H N N 91  
ARG   HXT  H N N 92  
ASN   N    N N N 93  
ASN   CA   C N S 94  
ASN   C    C N N 95  
ASN   O    O N N 96  
ASN   CB   C N N 97  
ASN   CG   C N N 98  
ASN   OD1  O N N 99  
ASN   ND2  N N N 100 
ASN   OXT  O N N 101 
ASN   H    H N N 102 
ASN   H2   H N N 103 
ASN   HA   H N N 104 
ASN   HB2  H N N 105 
ASN   HB3  H N N 106 
ASN   HD21 H N N 107 
ASN   HD22 H N N 108 
ASN   HXT  H N N 109 
ASP   N    N N N 110 
ASP   CA   C N S 111 
ASP   C    C N N 112 
ASP   O    O N N 113 
ASP   CB   C N N 114 
ASP   CG   C N N 115 
ASP   OD1  O N N 116 
ASP   OD2  O N N 117 
ASP   OXT  O N N 118 
ASP   H    H N N 119 
ASP   H2   H N N 120 
ASP   HA   H N N 121 
ASP   HB2  H N N 122 
ASP   HB3  H N N 123 
ASP   HD2  H N N 124 
ASP   HXT  H N N 125 
CYS   N    N N N 126 
CYS   CA   C N R 127 
CYS   C    C N N 128 
CYS   O    O N N 129 
CYS   CB   C N N 130 
CYS   SG   S N N 131 
CYS   OXT  O N N 132 
CYS   H    H N N 133 
CYS   H2   H N N 134 
CYS   HA   H N N 135 
CYS   HB2  H N N 136 
CYS   HB3  H N N 137 
CYS   HG   H N N 138 
CYS   HXT  H N N 139 
DTY   N    N N N 140 
DTY   CA   C N R 141 
DTY   C    C N N 142 
DTY   O    O N N 143 
DTY   CB   C N N 144 
DTY   CG   C Y N 145 
DTY   CD1  C Y N 146 
DTY   CD2  C Y N 147 
DTY   CE1  C Y N 148 
DTY   CE2  C Y N 149 
DTY   CZ   C Y N 150 
DTY   OH   O N N 151 
DTY   OXT  O N N 152 
DTY   H    H N N 153 
DTY   H2   H N N 154 
DTY   HA   H N N 155 
DTY   HB2  H N N 156 
DTY   HB3  H N N 157 
DTY   HD1  H N N 158 
DTY   HD2  H N N 159 
DTY   HE1  H N N 160 
DTY   HE2  H N N 161 
DTY   HH   H N N 162 
DTY   HXT  H N N 163 
GLN   N    N N N 164 
GLN   CA   C N S 165 
GLN   C    C N N 166 
GLN   O    O N N 167 
GLN   CB   C N N 168 
GLN   CG   C N N 169 
GLN   CD   C N N 170 
GLN   OE1  O N N 171 
GLN   NE2  N N N 172 
GLN   OXT  O N N 173 
GLN   H    H N N 174 
GLN   H2   H N N 175 
GLN   HA   H N N 176 
GLN   HB2  H N N 177 
GLN   HB3  H N N 178 
GLN   HG2  H N N 179 
GLN   HG3  H N N 180 
GLN   HE21 H N N 181 
GLN   HE22 H N N 182 
GLN   HXT  H N N 183 
GLU   N    N N N 184 
GLU   CA   C N S 185 
GLU   C    C N N 186 
GLU   O    O N N 187 
GLU   CB   C N N 188 
GLU   CG   C N N 189 
GLU   CD   C N N 190 
GLU   OE1  O N N 191 
GLU   OE2  O N N 192 
GLU   OXT  O N N 193 
GLU   H    H N N 194 
GLU   H2   H N N 195 
GLU   HA   H N N 196 
GLU   HB2  H N N 197 
GLU   HB3  H N N 198 
GLU   HG2  H N N 199 
GLU   HG3  H N N 200 
GLU   HE2  H N N 201 
GLU   HXT  H N N 202 
GLY   N    N N N 203 
GLY   CA   C N N 204 
GLY   C    C N N 205 
GLY   O    O N N 206 
GLY   OXT  O N N 207 
GLY   H    H N N 208 
GLY   H2   H N N 209 
GLY   HA2  H N N 210 
GLY   HA3  H N N 211 
GLY   HXT  H N N 212 
HIS   N    N N N 213 
HIS   CA   C N S 214 
HIS   C    C N N 215 
HIS   O    O N N 216 
HIS   CB   C N N 217 
HIS   CG   C Y N 218 
HIS   ND1  N Y N 219 
HIS   CD2  C Y N 220 
HIS   CE1  C Y N 221 
HIS   NE2  N Y N 222 
HIS   OXT  O N N 223 
HIS   H    H N N 224 
HIS   H2   H N N 225 
HIS   HA   H N N 226 
HIS   HB2  H N N 227 
HIS   HB3  H N N 228 
HIS   HD1  H N N 229 
HIS   HD2  H N N 230 
HIS   HE1  H N N 231 
HIS   HE2  H N N 232 
HIS   HXT  H N N 233 
HOH   O    O N N 234 
HOH   H1   H N N 235 
HOH   H2   H N N 236 
ILE   N    N N N 237 
ILE   CA   C N S 238 
ILE   C    C N N 239 
ILE   O    O N N 240 
ILE   CB   C N S 241 
ILE   CG1  C N N 242 
ILE   CG2  C N N 243 
ILE   CD1  C N N 244 
ILE   OXT  O N N 245 
ILE   H    H N N 246 
ILE   H2   H N N 247 
ILE   HA   H N N 248 
ILE   HB   H N N 249 
ILE   HG12 H N N 250 
ILE   HG13 H N N 251 
ILE   HG21 H N N 252 
ILE   HG22 H N N 253 
ILE   HG23 H N N 254 
ILE   HD11 H N N 255 
ILE   HD12 H N N 256 
ILE   HD13 H N N 257 
ILE   HXT  H N N 258 
LEU   N    N N N 259 
LEU   CA   C N S 260 
LEU   C    C N N 261 
LEU   O    O N N 262 
LEU   CB   C N N 263 
LEU   CG   C N N 264 
LEU   CD1  C N N 265 
LEU   CD2  C N N 266 
LEU   OXT  O N N 267 
LEU   H    H N N 268 
LEU   H2   H N N 269 
LEU   HA   H N N 270 
LEU   HB2  H N N 271 
LEU   HB3  H N N 272 
LEU   HG   H N N 273 
LEU   HD11 H N N 274 
LEU   HD12 H N N 275 
LEU   HD13 H N N 276 
LEU   HD21 H N N 277 
LEU   HD22 H N N 278 
LEU   HD23 H N N 279 
LEU   HXT  H N N 280 
LYS   N    N N N 281 
LYS   CA   C N S 282 
LYS   C    C N N 283 
LYS   O    O N N 284 
LYS   CB   C N N 285 
LYS   CG   C N N 286 
LYS   CD   C N N 287 
LYS   CE   C N N 288 
LYS   NZ   N N N 289 
LYS   OXT  O N N 290 
LYS   H    H N N 291 
LYS   H2   H N N 292 
LYS   HA   H N N 293 
LYS   HB2  H N N 294 
LYS   HB3  H N N 295 
LYS   HG2  H N N 296 
LYS   HG3  H N N 297 
LYS   HD2  H N N 298 
LYS   HD3  H N N 299 
LYS   HE2  H N N 300 
LYS   HE3  H N N 301 
LYS   HZ1  H N N 302 
LYS   HZ2  H N N 303 
LYS   HZ3  H N N 304 
LYS   HXT  H N N 305 
MET   N    N N N 306 
MET   CA   C N S 307 
MET   C    C N N 308 
MET   O    O N N 309 
MET   CB   C N N 310 
MET   CG   C N N 311 
MET   SD   S N N 312 
MET   CE   C N N 313 
MET   OXT  O N N 314 
MET   H    H N N 315 
MET   H2   H N N 316 
MET   HA   H N N 317 
MET   HB2  H N N 318 
MET   HB3  H N N 319 
MET   HG2  H N N 320 
MET   HG3  H N N 321 
MET   HE1  H N N 322 
MET   HE2  H N N 323 
MET   HE3  H N N 324 
MET   HXT  H N N 325 
PHE   N    N N N 326 
PHE   CA   C N S 327 
PHE   C    C N N 328 
PHE   O    O N N 329 
PHE   CB   C N N 330 
PHE   CG   C Y N 331 
PHE   CD1  C Y N 332 
PHE   CD2  C Y N 333 
PHE   CE1  C Y N 334 
PHE   CE2  C Y N 335 
PHE   CZ   C Y N 336 
PHE   OXT  O N N 337 
PHE   H    H N N 338 
PHE   H2   H N N 339 
PHE   HA   H N N 340 
PHE   HB2  H N N 341 
PHE   HB3  H N N 342 
PHE   HD1  H N N 343 
PHE   HD2  H N N 344 
PHE   HE1  H N N 345 
PHE   HE2  H N N 346 
PHE   HZ   H N N 347 
PHE   HXT  H N N 348 
PRO   N    N N N 349 
PRO   CA   C N S 350 
PRO   C    C N N 351 
PRO   O    O N N 352 
PRO   CB   C N N 353 
PRO   CG   C N N 354 
PRO   CD   C N N 355 
PRO   OXT  O N N 356 
PRO   H    H N N 357 
PRO   HA   H N N 358 
PRO   HB2  H N N 359 
PRO   HB3  H N N 360 
PRO   HG2  H N N 361 
PRO   HG3  H N N 362 
PRO   HD2  H N N 363 
PRO   HD3  H N N 364 
PRO   HXT  H N N 365 
SER   N    N N N 366 
SER   CA   C N S 367 
SER   C    C N N 368 
SER   O    O N N 369 
SER   CB   C N N 370 
SER   OG   O N N 371 
SER   OXT  O N N 372 
SER   H    H N N 373 
SER   H2   H N N 374 
SER   HA   H N N 375 
SER   HB2  H N N 376 
SER   HB3  H N N 377 
SER   HG   H N N 378 
SER   HXT  H N N 379 
THR   N    N N N 380 
THR   CA   C N S 381 
THR   C    C N N 382 
THR   O    O N N 383 
THR   CB   C N R 384 
THR   OG1  O N N 385 
THR   CG2  C N N 386 
THR   OXT  O N N 387 
THR   H    H N N 388 
THR   H2   H N N 389 
THR   HA   H N N 390 
THR   HB   H N N 391 
THR   HG1  H N N 392 
THR   HG21 H N N 393 
THR   HG22 H N N 394 
THR   HG23 H N N 395 
THR   HXT  H N N 396 
TRP   N    N N N 397 
TRP   CA   C N S 398 
TRP   C    C N N 399 
TRP   O    O N N 400 
TRP   CB   C N N 401 
TRP   CG   C Y N 402 
TRP   CD1  C Y N 403 
TRP   CD2  C Y N 404 
TRP   NE1  N Y N 405 
TRP   CE2  C Y N 406 
TRP   CE3  C Y N 407 
TRP   CZ2  C Y N 408 
TRP   CZ3  C Y N 409 
TRP   CH2  C Y N 410 
TRP   OXT  O N N 411 
TRP   H    H N N 412 
TRP   H2   H N N 413 
TRP   HA   H N N 414 
TRP   HB2  H N N 415 
TRP   HB3  H N N 416 
TRP   HD1  H N N 417 
TRP   HE1  H N N 418 
TRP   HE3  H N N 419 
TRP   HZ2  H N N 420 
TRP   HZ3  H N N 421 
TRP   HH2  H N N 422 
TRP   HXT  H N N 423 
TYR   N    N N N 424 
TYR   CA   C N S 425 
TYR   C    C N N 426 
TYR   O    O N N 427 
TYR   CB   C N N 428 
TYR   CG   C Y N 429 
TYR   CD1  C Y N 430 
TYR   CD2  C Y N 431 
TYR   CE1  C Y N 432 
TYR   CE2  C Y N 433 
TYR   CZ   C Y N 434 
TYR   OH   O N N 435 
TYR   OXT  O N N 436 
TYR   H    H N N 437 
TYR   H2   H N N 438 
TYR   HA   H N N 439 
TYR   HB2  H N N 440 
TYR   HB3  H N N 441 
TYR   HD1  H N N 442 
TYR   HD2  H N N 443 
TYR   HE1  H N N 444 
TYR   HE2  H N N 445 
TYR   HH   H N N 446 
TYR   HXT  H N N 447 
VAL   N    N N N 448 
VAL   CA   C N S 449 
VAL   C    C N N 450 
VAL   O    O N N 451 
VAL   CB   C N N 452 
VAL   CG1  C N N 453 
VAL   CG2  C N N 454 
VAL   OXT  O N N 455 
VAL   H    H N N 456 
VAL   H2   H N N 457 
VAL   HA   H N N 458 
VAL   HB   H N N 459 
VAL   HG11 H N N 460 
VAL   HG12 H N N 461 
VAL   HG13 H N N 462 
VAL   HG21 H N N 463 
VAL   HG22 H N N 464 
VAL   HG23 H N N 465 
VAL   HXT  H N N 466 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AMA C39 S38  sing N N 1   
A1AMA O41 S38  doub N N 2   
A1AMA S38 O40  doub N N 3   
A1AMA S38 C37  sing N N 4   
A1AMA C37 C36  sing N N 5   
A1AMA C36 C30  sing N N 6   
A1AMA C30 N29  sing N N 7   
A1AMA C30 C31  sing N N 8   
A1AMA C31 C32  sing N N 9   
A1AMA C32 C33  sing N N 10  
A1AMA N34 C33  sing N N 11  
A1AMA C33 O35  doub N N 12  
A1AMA C30 H1   sing N N 13  
A1AMA C31 H2   sing N N 14  
A1AMA C31 H3   sing N N 15  
A1AMA C32 H4   sing N N 16  
A1AMA C32 H5   sing N N 17  
A1AMA C36 H6   sing N N 18  
A1AMA C36 H7   sing N N 19  
A1AMA C37 H8   sing N N 20  
A1AMA C37 H9   sing N N 21  
A1AMA C39 H10  sing N N 22  
A1AMA C39 H11  sing N N 23  
A1AMA C39 H12  sing N N 24  
A1AMA N29 H13  sing N N 25  
A1AMA N29 H14  sing N N 26  
A1AMA N34 H16  sing N N 27  
A1AMA N34 H17  sing N N 28  
ABA   N   CA   sing N N 29  
ABA   N   H    sing N N 30  
ABA   N   H2   sing N N 31  
ABA   CA  C    sing N N 32  
ABA   CA  CB   sing N N 33  
ABA   CA  HA   sing N N 34  
ABA   C   O    doub N N 35  
ABA   C   OXT  sing N N 36  
ABA   CB  CG   sing N N 37  
ABA   CB  HB3  sing N N 38  
ABA   CB  HB2  sing N N 39  
ABA   CG  HG1  sing N N 40  
ABA   CG  HG3  sing N N 41  
ABA   CG  HG2  sing N N 42  
ABA   OXT HXT  sing N N 43  
ACE   C   O    doub N N 44  
ACE   C   CH3  sing N N 45  
ACE   C   H    sing N N 46  
ACE   CH3 H1   sing N N 47  
ACE   CH3 H2   sing N N 48  
ACE   CH3 H3   sing N N 49  
ALA   N   CA   sing N N 50  
ALA   N   H    sing N N 51  
ALA   N   H2   sing N N 52  
ALA   CA  C    sing N N 53  
ALA   CA  CB   sing N N 54  
ALA   CA  HA   sing N N 55  
ALA   C   O    doub N N 56  
ALA   C   OXT  sing N N 57  
ALA   CB  HB1  sing N N 58  
ALA   CB  HB2  sing N N 59  
ALA   CB  HB3  sing N N 60  
ALA   OXT HXT  sing N N 61  
ARG   N   CA   sing N N 62  
ARG   N   H    sing N N 63  
ARG   N   H2   sing N N 64  
ARG   CA  C    sing N N 65  
ARG   CA  CB   sing N N 66  
ARG   CA  HA   sing N N 67  
ARG   C   O    doub N N 68  
ARG   C   OXT  sing N N 69  
ARG   CB  CG   sing N N 70  
ARG   CB  HB2  sing N N 71  
ARG   CB  HB3  sing N N 72  
ARG   CG  CD   sing N N 73  
ARG   CG  HG2  sing N N 74  
ARG   CG  HG3  sing N N 75  
ARG   CD  NE   sing N N 76  
ARG   CD  HD2  sing N N 77  
ARG   CD  HD3  sing N N 78  
ARG   NE  CZ   sing N N 79  
ARG   NE  HE   sing N N 80  
ARG   CZ  NH1  sing N N 81  
ARG   CZ  NH2  doub N N 82  
ARG   NH1 HH11 sing N N 83  
ARG   NH1 HH12 sing N N 84  
ARG   NH2 HH21 sing N N 85  
ARG   NH2 HH22 sing N N 86  
ARG   OXT HXT  sing N N 87  
ASN   N   CA   sing N N 88  
ASN   N   H    sing N N 89  
ASN   N   H2   sing N N 90  
ASN   CA  C    sing N N 91  
ASN   CA  CB   sing N N 92  
ASN   CA  HA   sing N N 93  
ASN   C   O    doub N N 94  
ASN   C   OXT  sing N N 95  
ASN   CB  CG   sing N N 96  
ASN   CB  HB2  sing N N 97  
ASN   CB  HB3  sing N N 98  
ASN   CG  OD1  doub N N 99  
ASN   CG  ND2  sing N N 100 
ASN   ND2 HD21 sing N N 101 
ASN   ND2 HD22 sing N N 102 
ASN   OXT HXT  sing N N 103 
ASP   N   CA   sing N N 104 
ASP   N   H    sing N N 105 
ASP   N   H2   sing N N 106 
ASP   CA  C    sing N N 107 
ASP   CA  CB   sing N N 108 
ASP   CA  HA   sing N N 109 
ASP   C   O    doub N N 110 
ASP   C   OXT  sing N N 111 
ASP   CB  CG   sing N N 112 
ASP   CB  HB2  sing N N 113 
ASP   CB  HB3  sing N N 114 
ASP   CG  OD1  doub N N 115 
ASP   CG  OD2  sing N N 116 
ASP   OD2 HD2  sing N N 117 
ASP   OXT HXT  sing N N 118 
CYS   N   CA   sing N N 119 
CYS   N   H    sing N N 120 
CYS   N   H2   sing N N 121 
CYS   CA  C    sing N N 122 
CYS   CA  CB   sing N N 123 
CYS   CA  HA   sing N N 124 
CYS   C   O    doub N N 125 
CYS   C   OXT  sing N N 126 
CYS   CB  SG   sing N N 127 
CYS   CB  HB2  sing N N 128 
CYS   CB  HB3  sing N N 129 
CYS   SG  HG   sing N N 130 
CYS   OXT HXT  sing N N 131 
DTY   N   CA   sing N N 132 
DTY   N   H    sing N N 133 
DTY   N   H2   sing N N 134 
DTY   CA  C    sing N N 135 
DTY   CA  CB   sing N N 136 
DTY   CA  HA   sing N N 137 
DTY   C   O    doub N N 138 
DTY   C   OXT  sing N N 139 
DTY   CB  CG   sing N N 140 
DTY   CB  HB2  sing N N 141 
DTY   CB  HB3  sing N N 142 
DTY   CG  CD1  doub Y N 143 
DTY   CG  CD2  sing Y N 144 
DTY   CD1 CE1  sing Y N 145 
DTY   CD1 HD1  sing N N 146 
DTY   CD2 CE2  doub Y N 147 
DTY   CD2 HD2  sing N N 148 
DTY   CE1 CZ   doub Y N 149 
DTY   CE1 HE1  sing N N 150 
DTY   CE2 CZ   sing Y N 151 
DTY   CE2 HE2  sing N N 152 
DTY   CZ  OH   sing N N 153 
DTY   OH  HH   sing N N 154 
DTY   OXT HXT  sing N N 155 
GLN   N   CA   sing N N 156 
GLN   N   H    sing N N 157 
GLN   N   H2   sing N N 158 
GLN   CA  C    sing N N 159 
GLN   CA  CB   sing N N 160 
GLN   CA  HA   sing N N 161 
GLN   C   O    doub N N 162 
GLN   C   OXT  sing N N 163 
GLN   CB  CG   sing N N 164 
GLN   CB  HB2  sing N N 165 
GLN   CB  HB3  sing N N 166 
GLN   CG  CD   sing N N 167 
GLN   CG  HG2  sing N N 168 
GLN   CG  HG3  sing N N 169 
GLN   CD  OE1  doub N N 170 
GLN   CD  NE2  sing N N 171 
GLN   NE2 HE21 sing N N 172 
GLN   NE2 HE22 sing N N 173 
GLN   OXT HXT  sing N N 174 
GLU   N   CA   sing N N 175 
GLU   N   H    sing N N 176 
GLU   N   H2   sing N N 177 
GLU   CA  C    sing N N 178 
GLU   CA  CB   sing N N 179 
GLU   CA  HA   sing N N 180 
GLU   C   O    doub N N 181 
GLU   C   OXT  sing N N 182 
GLU   CB  CG   sing N N 183 
GLU   CB  HB2  sing N N 184 
GLU   CB  HB3  sing N N 185 
GLU   CG  CD   sing N N 186 
GLU   CG  HG2  sing N N 187 
GLU   CG  HG3  sing N N 188 
GLU   CD  OE1  doub N N 189 
GLU   CD  OE2  sing N N 190 
GLU   OE2 HE2  sing N N 191 
GLU   OXT HXT  sing N N 192 
GLY   N   CA   sing N N 193 
GLY   N   H    sing N N 194 
GLY   N   H2   sing N N 195 
GLY   CA  C    sing N N 196 
GLY   CA  HA2  sing N N 197 
GLY   CA  HA3  sing N N 198 
GLY   C   O    doub N N 199 
GLY   C   OXT  sing N N 200 
GLY   OXT HXT  sing N N 201 
HIS   N   CA   sing N N 202 
HIS   N   H    sing N N 203 
HIS   N   H2   sing N N 204 
HIS   CA  C    sing N N 205 
HIS   CA  CB   sing N N 206 
HIS   CA  HA   sing N N 207 
HIS   C   O    doub N N 208 
HIS   C   OXT  sing N N 209 
HIS   CB  CG   sing N N 210 
HIS   CB  HB2  sing N N 211 
HIS   CB  HB3  sing N N 212 
HIS   CG  ND1  sing Y N 213 
HIS   CG  CD2  doub Y N 214 
HIS   ND1 CE1  doub Y N 215 
HIS   ND1 HD1  sing N N 216 
HIS   CD2 NE2  sing Y N 217 
HIS   CD2 HD2  sing N N 218 
HIS   CE1 NE2  sing Y N 219 
HIS   CE1 HE1  sing N N 220 
HIS   NE2 HE2  sing N N 221 
HIS   OXT HXT  sing N N 222 
HOH   O   H1   sing N N 223 
HOH   O   H2   sing N N 224 
ILE   N   CA   sing N N 225 
ILE   N   H    sing N N 226 
ILE   N   H2   sing N N 227 
ILE   CA  C    sing N N 228 
ILE   CA  CB   sing N N 229 
ILE   CA  HA   sing N N 230 
ILE   C   O    doub N N 231 
ILE   C   OXT  sing N N 232 
ILE   CB  CG1  sing N N 233 
ILE   CB  CG2  sing N N 234 
ILE   CB  HB   sing N N 235 
ILE   CG1 CD1  sing N N 236 
ILE   CG1 HG12 sing N N 237 
ILE   CG1 HG13 sing N N 238 
ILE   CG2 HG21 sing N N 239 
ILE   CG2 HG22 sing N N 240 
ILE   CG2 HG23 sing N N 241 
ILE   CD1 HD11 sing N N 242 
ILE   CD1 HD12 sing N N 243 
ILE   CD1 HD13 sing N N 244 
ILE   OXT HXT  sing N N 245 
LEU   N   CA   sing N N 246 
LEU   N   H    sing N N 247 
LEU   N   H2   sing N N 248 
LEU   CA  C    sing N N 249 
LEU   CA  CB   sing N N 250 
LEU   CA  HA   sing N N 251 
LEU   C   O    doub N N 252 
LEU   C   OXT  sing N N 253 
LEU   CB  CG   sing N N 254 
LEU   CB  HB2  sing N N 255 
LEU   CB  HB3  sing N N 256 
LEU   CG  CD1  sing N N 257 
LEU   CG  CD2  sing N N 258 
LEU   CG  HG   sing N N 259 
LEU   CD1 HD11 sing N N 260 
LEU   CD1 HD12 sing N N 261 
LEU   CD1 HD13 sing N N 262 
LEU   CD2 HD21 sing N N 263 
LEU   CD2 HD22 sing N N 264 
LEU   CD2 HD23 sing N N 265 
LEU   OXT HXT  sing N N 266 
LYS   N   CA   sing N N 267 
LYS   N   H    sing N N 268 
LYS   N   H2   sing N N 269 
LYS   CA  C    sing N N 270 
LYS   CA  CB   sing N N 271 
LYS   CA  HA   sing N N 272 
LYS   C   O    doub N N 273 
LYS   C   OXT  sing N N 274 
LYS   CB  CG   sing N N 275 
LYS   CB  HB2  sing N N 276 
LYS   CB  HB3  sing N N 277 
LYS   CG  CD   sing N N 278 
LYS   CG  HG2  sing N N 279 
LYS   CG  HG3  sing N N 280 
LYS   CD  CE   sing N N 281 
LYS   CD  HD2  sing N N 282 
LYS   CD  HD3  sing N N 283 
LYS   CE  NZ   sing N N 284 
LYS   CE  HE2  sing N N 285 
LYS   CE  HE3  sing N N 286 
LYS   NZ  HZ1  sing N N 287 
LYS   NZ  HZ2  sing N N 288 
LYS   NZ  HZ3  sing N N 289 
LYS   OXT HXT  sing N N 290 
MET   N   CA   sing N N 291 
MET   N   H    sing N N 292 
MET   N   H2   sing N N 293 
MET   CA  C    sing N N 294 
MET   CA  CB   sing N N 295 
MET   CA  HA   sing N N 296 
MET   C   O    doub N N 297 
MET   C   OXT  sing N N 298 
MET   CB  CG   sing N N 299 
MET   CB  HB2  sing N N 300 
MET   CB  HB3  sing N N 301 
MET   CG  SD   sing N N 302 
MET   CG  HG2  sing N N 303 
MET   CG  HG3  sing N N 304 
MET   SD  CE   sing N N 305 
MET   CE  HE1  sing N N 306 
MET   CE  HE2  sing N N 307 
MET   CE  HE3  sing N N 308 
MET   OXT HXT  sing N N 309 
PHE   N   CA   sing N N 310 
PHE   N   H    sing N N 311 
PHE   N   H2   sing N N 312 
PHE   CA  C    sing N N 313 
PHE   CA  CB   sing N N 314 
PHE   CA  HA   sing N N 315 
PHE   C   O    doub N N 316 
PHE   C   OXT  sing N N 317 
PHE   CB  CG   sing N N 318 
PHE   CB  HB2  sing N N 319 
PHE   CB  HB3  sing N N 320 
PHE   CG  CD1  doub Y N 321 
PHE   CG  CD2  sing Y N 322 
PHE   CD1 CE1  sing Y N 323 
PHE   CD1 HD1  sing N N 324 
PHE   CD2 CE2  doub Y N 325 
PHE   CD2 HD2  sing N N 326 
PHE   CE1 CZ   doub Y N 327 
PHE   CE1 HE1  sing N N 328 
PHE   CE2 CZ   sing Y N 329 
PHE   CE2 HE2  sing N N 330 
PHE   CZ  HZ   sing N N 331 
PHE   OXT HXT  sing N N 332 
PRO   N   CA   sing N N 333 
PRO   N   CD   sing N N 334 
PRO   N   H    sing N N 335 
PRO   CA  C    sing N N 336 
PRO   CA  CB   sing N N 337 
PRO   CA  HA   sing N N 338 
PRO   C   O    doub N N 339 
PRO   C   OXT  sing N N 340 
PRO   CB  CG   sing N N 341 
PRO   CB  HB2  sing N N 342 
PRO   CB  HB3  sing N N 343 
PRO   CG  CD   sing N N 344 
PRO   CG  HG2  sing N N 345 
PRO   CG  HG3  sing N N 346 
PRO   CD  HD2  sing N N 347 
PRO   CD  HD3  sing N N 348 
PRO   OXT HXT  sing N N 349 
SER   N   CA   sing N N 350 
SER   N   H    sing N N 351 
SER   N   H2   sing N N 352 
SER   CA  C    sing N N 353 
SER   CA  CB   sing N N 354 
SER   CA  HA   sing N N 355 
SER   C   O    doub N N 356 
SER   C   OXT  sing N N 357 
SER   CB  OG   sing N N 358 
SER   CB  HB2  sing N N 359 
SER   CB  HB3  sing N N 360 
SER   OG  HG   sing N N 361 
SER   OXT HXT  sing N N 362 
THR   N   CA   sing N N 363 
THR   N   H    sing N N 364 
THR   N   H2   sing N N 365 
THR   CA  C    sing N N 366 
THR   CA  CB   sing N N 367 
THR   CA  HA   sing N N 368 
THR   C   O    doub N N 369 
THR   C   OXT  sing N N 370 
THR   CB  OG1  sing N N 371 
THR   CB  CG2  sing N N 372 
THR   CB  HB   sing N N 373 
THR   OG1 HG1  sing N N 374 
THR   CG2 HG21 sing N N 375 
THR   CG2 HG22 sing N N 376 
THR   CG2 HG23 sing N N 377 
THR   OXT HXT  sing N N 378 
TRP   N   CA   sing N N 379 
TRP   N   H    sing N N 380 
TRP   N   H2   sing N N 381 
TRP   CA  C    sing N N 382 
TRP   CA  CB   sing N N 383 
TRP   CA  HA   sing N N 384 
TRP   C   O    doub N N 385 
TRP   C   OXT  sing N N 386 
TRP   CB  CG   sing N N 387 
TRP   CB  HB2  sing N N 388 
TRP   CB  HB3  sing N N 389 
TRP   CG  CD1  doub Y N 390 
TRP   CG  CD2  sing Y N 391 
TRP   CD1 NE1  sing Y N 392 
TRP   CD1 HD1  sing N N 393 
TRP   CD2 CE2  doub Y N 394 
TRP   CD2 CE3  sing Y N 395 
TRP   NE1 CE2  sing Y N 396 
TRP   NE1 HE1  sing N N 397 
TRP   CE2 CZ2  sing Y N 398 
TRP   CE3 CZ3  doub Y N 399 
TRP   CE3 HE3  sing N N 400 
TRP   CZ2 CH2  doub Y N 401 
TRP   CZ2 HZ2  sing N N 402 
TRP   CZ3 CH2  sing Y N 403 
TRP   CZ3 HZ3  sing N N 404 
TRP   CH2 HH2  sing N N 405 
TRP   OXT HXT  sing N N 406 
TYR   N   CA   sing N N 407 
TYR   N   H    sing N N 408 
TYR   N   H2   sing N N 409 
TYR   CA  C    sing N N 410 
TYR   CA  CB   sing N N 411 
TYR   CA  HA   sing N N 412 
TYR   C   O    doub N N 413 
TYR   C   OXT  sing N N 414 
TYR   CB  CG   sing N N 415 
TYR   CB  HB2  sing N N 416 
TYR   CB  HB3  sing N N 417 
TYR   CG  CD1  doub Y N 418 
TYR   CG  CD2  sing Y N 419 
TYR   CD1 CE1  sing Y N 420 
TYR   CD1 HD1  sing N N 421 
TYR   CD2 CE2  doub Y N 422 
TYR   CD2 HD2  sing N N 423 
TYR   CE1 CZ   doub Y N 424 
TYR   CE1 HE1  sing N N 425 
TYR   CE2 CZ   sing Y N 426 
TYR   CE2 HE2  sing N N 427 
TYR   CZ  OH   sing N N 428 
TYR   OH  HH   sing N N 429 
TYR   OXT HXT  sing N N 430 
VAL   N   CA   sing N N 431 
VAL   N   H    sing N N 432 
VAL   N   H2   sing N N 433 
VAL   CA  C    sing N N 434 
VAL   CA  CB   sing N N 435 
VAL   CA  HA   sing N N 436 
VAL   C   O    doub N N 437 
VAL   C   OXT  sing N N 438 
VAL   CB  CG1  sing N N 439 
VAL   CB  CG2  sing N N 440 
VAL   CB  HB   sing N N 441 
VAL   CG1 HG11 sing N N 442 
VAL   CG1 HG12 sing N N 443 
VAL   CG1 HG13 sing N N 444 
VAL   CG2 HG21 sing N N 445 
VAL   CG2 HG22 sing N N 446 
VAL   CG2 HG23 sing N N 447 
VAL   OXT HXT  sing N N 448 
# 
loop_
_pdbx_audit_support.funding_organization 
_pdbx_audit_support.country 
_pdbx_audit_support.grant_number 
_pdbx_audit_support.ordinal 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R01GM115568 1 
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 'United States' R01GM128731 2 
'Cancer Prevention and Research Institute of Texas (CPRIT)'                                'United States' RR200030    3 
# 
_pdbx_initial_refinement_model.id               1 
_pdbx_initial_refinement_model.entity_id_list   ? 
_pdbx_initial_refinement_model.type             'experimental model' 
_pdbx_initial_refinement_model.source_name      PDB 
_pdbx_initial_refinement_model.accession_code   ? 
_pdbx_initial_refinement_model.details          ? 
# 
_space_group.name_H-M_alt     'P 1 21 1' 
_space_group.name_Hall        'P 2yb' 
_space_group.IT_number        4 
_space_group.crystal_system   monoclinic 
_space_group.id               1 
# 
_atom_sites.entry_id                    9BC1 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   0.018113 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.005823 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   0.010138 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   0.017762 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
_atom_type.scat_dispersion_real 
_atom_type.scat_dispersion_imag 
_atom_type.scat_Cromer_Mann_a1 
_atom_type.scat_Cromer_Mann_a2 
_atom_type.scat_Cromer_Mann_a3 
_atom_type.scat_Cromer_Mann_a4 
_atom_type.scat_Cromer_Mann_b1 
_atom_type.scat_Cromer_Mann_b2 
_atom_type.scat_Cromer_Mann_b3 
_atom_type.scat_Cromer_Mann_b4 
_atom_type.scat_Cromer_Mann_c 
_atom_type.scat_source 
_atom_type.scat_dispersion_source 
C   ? ? 3.54356 2.42580 ? ? 25.62398 1.50364  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
N   ? ? 4.01032 2.96436 ? ? 19.97189 1.75589  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O   ? ? 4.49882 3.47563 ? ? 15.80542 1.70748  ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
O1- ? ? 5.12366 3.84317 ? ? 3.49406  27.47979 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
S   ? ? 9.55732 6.39887 ? ? 1.23737  29.19336 ? ? 0.0 
;2-Gaussian fit: Grosse-Kunstleve RW, Sauter NK, Adams PD: Newsletter of the IUCr Commission on Crystallographic Computing 2004, 3, 22-31.
;
? 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . GLY   A 1 2   ? -27.41304 4.41716   -19.27563 1.000 45.95405 ?  2   GLY   A N   1 
ATOM   2    C CA  . GLY   A 1 2   ? -26.93997 3.87393   -18.02151 1.000 44.67636 ?  2   GLY   A CA  1 
ATOM   3    C C   . GLY   A 1 2   ? -25.59766 3.19092   -18.19377 1.000 52.76655 ?  2   GLY   A C   1 
ATOM   4    O O   . GLY   A 1 2   ? -25.28857 2.68889   -19.27918 1.000 52.32375 ?  2   GLY   A O   1 
ATOM   5    N N   . PHE   A 1 3   ? -24.80912 3.17686   -17.12029 1.000 49.02861 ?  3   PHE   A N   1 
ATOM   6    C CA  . PHE   A 1 3   ? -23.49284 2.55209   -17.08839 1.000 49.64767 ?  3   PHE   A CA  1 
ATOM   7    C C   . PHE   A 1 3   ? -23.52265 1.40429   -16.09331 1.000 48.79765 ?  3   PHE   A C   1 
ATOM   8    O O   . PHE   A 1 3   ? -23.71130 1.62769   -14.89202 1.000 50.10457 ?  3   PHE   A O   1 
ATOM   9    C CB  . PHE   A 1 3   ? -22.41654 3.56056   -16.69839 1.000 54.08250 ?  3   PHE   A CB  1 
ATOM   10   C CG  . PHE   A 1 3   ? -21.50754 3.92956   -17.82569 1.000 56.25009 ?  3   PHE   A CG  1 
ATOM   11   C CD1 . PHE   A 1 3   ? -20.90137 2.94571   -18.58967 1.000 54.29703 ?  3   PHE   A CD1 1 
ATOM   12   C CD2 . PHE   A 1 3   ? -21.27682 5.25850   -18.13385 1.000 53.91507 ?  3   PHE   A CD2 1 
ATOM   13   C CE1 . PHE   A 1 3   ? -20.07259 3.27978   -19.63097 1.000 54.51880 ?  3   PHE   A CE1 1 
ATOM   14   C CE2 . PHE   A 1 3   ? -20.45295 5.60164   -19.17361 1.000 54.34233 ?  3   PHE   A CE2 1 
ATOM   15   C CZ  . PHE   A 1 3   ? -19.84777 4.60796   -19.92356 1.000 55.92441 ?  3   PHE   A CZ  1 
ATOM   16   N N   . ARG   A 1 4   ? -23.33254 0.18277   -16.59161 1.000 45.34865 ?  4   ARG   A N   1 
ATOM   17   C CA  . ARG   A 1 4   ? -23.39662 -1.01562  -15.76888 1.000 43.85114 ?  4   ARG   A CA  1 
ATOM   18   C C   . ARG   A 1 4   ? -22.18205 -1.88529  -16.06065 1.000 37.39852 ?  4   ARG   A C   1 
ATOM   19   O O   . ARG   A 1 4   ? -21.70589 -1.93487  -17.19438 1.000 39.61059 ?  4   ARG   A O   1 
ATOM   20   C CB  . ARG   A 1 4   ? -24.67647 -1.81763  -16.05166 1.000 41.24179 ?  4   ARG   A CB  1 
ATOM   21   C CG  . ARG   A 1 4   ? -25.96609 -1.00796  -15.89537 1.000 43.06951 ?  4   ARG   A CG  1 
ATOM   22   C CD  . ARG   A 1 4   ? -26.97675 -1.80930  -15.12755 1.000 43.13482 ?  4   ARG   A CD  1 
ATOM   23   N NE  . ARG   A 1 4   ? -26.28964 -2.72351  -14.22637 1.000 43.09533 ?  4   ARG   A NE  1 
ATOM   24   C CZ  . ARG   A 1 4   ? -26.90643 -3.57407  -13.42115 1.000 42.08079 ?  4   ARG   A CZ  1 
ATOM   25   N NH1 . ARG   A 1 4   ? -28.22797 -3.64373  -13.38493 1.000 45.23489 ?  4   ARG   A NH1 1 
ATOM   26   N NH2 . ARG   A 1 4   ? -26.18185 -4.38932  -12.65197 1.000 37.56665 ?  4   ARG   A NH2 1 
ATOM   27   N N   . LYS   A 1 5   ? -21.68891 -2.57791  -15.04393 1.000 38.38495 ?  5   LYS   A N   1 
ATOM   28   C CA  . LYS   A 1 5   ? -20.75290 -3.66139  -15.32384 1.000 38.24871 ?  5   LYS   A CA  1 
ATOM   29   C C   . LYS   A 1 5   ? -21.52110 -4.77087  -16.02188 1.000 30.22968 ?  5   LYS   A C   1 
ATOM   30   O O   . LYS   A 1 5   ? -22.48483 -5.30358  -15.46942 1.000 34.15953 ?  5   LYS   A O   1 
ATOM   31   C CB  . LYS   A 1 5   ? -20.08940 -4.17177  -14.05299 1.000 39.75349 ?  5   LYS   A CB  1 
ATOM   32   C CG  . LYS   A 1 5   ? -18.98694 -3.24799  -13.52754 1.000 44.43692 ?  5   LYS   A CG  1 
ATOM   33   C CD  . LYS   A 1 5   ? -18.40670 -3.77307  -12.23218 1.000 48.26507 ?  5   LYS   A CD  1 
ATOM   34   C CE  . LYS   A 1 5   ? -17.33822 -4.81800  -12.48648 1.000 44.62944 ?  5   LYS   A CE  1 
ATOM   35   N NZ  . LYS   A 1 5   ? -16.00415 -4.43140  -11.88362 1.000 40.00556 ?  5   LYS   A NZ  1 
ATOM   36   N N   . MET   A 1 6   ? -21.12079 -5.08569  -17.24514 1.000 30.33071 ?  6   MET   A N   1 
ATOM   37   C CA  . MET   A 1 6   ? -21.84158 -6.01362  -18.10511 1.000 25.51244 ?  6   MET   A CA  1 
ATOM   38   C C   . MET   A 1 6   ? -20.95163 -7.19775  -18.46552 1.000 27.88089 ?  6   MET   A C   1 
ATOM   39   O O   . MET   A 1 6   ? -19.80647 -7.00157  -18.87311 1.000 33.37816 ?  6   MET   A O   1 
ATOM   40   C CB  . MET   A 1 6   ? -22.28163 -5.26107  -19.35800 1.000 32.39205 ?  6   MET   A CB  1 
ATOM   41   C CG  . MET   A 1 6   ? -23.04212 -6.00926  -20.35737 1.000 36.07094 ?  6   MET   A CG  1 
ATOM   42   S SD  . MET   A 1 6   ? -23.67403 -4.73775  -21.48173 1.000 41.28337 ?  6   MET   A SD  1 
ATOM   43   C CE  . MET   A 1 6   ? -24.46238 -3.58861  -20.36983 1.000 34.02153 ?  6   MET   A CE  1 
ATOM   44   N N   . ALA   A 1 7   ? -21.47265 -8.41905  -18.33572 1.000 25.22825 ?  7   ALA   A N   1 
ATOM   45   C CA  . ALA   A 1 7   ? -20.70847 -9.57979  -18.77380 1.000 22.57764 ?  7   ALA   A CA  1 
ATOM   46   C C   . ALA   A 1 7   ? -21.00049 -9.87663  -20.24174 1.000 25.69072 ?  7   ALA   A C   1 
ATOM   47   O O   . ALA   A 1 7   ? -22.00886 -9.43242  -20.79668 1.000 24.96557 ?  7   ALA   A O   1 
ATOM   48   C CB  . ALA   A 1 7   ? -21.04778 -10.80025 -17.90947 1.000 25.61328 ?  7   ALA   A CB  1 
ATOM   49   N N   . PHE   A 1 8   ? -20.11326 -10.64749 -20.87727 1.000 24.07798 ?  8   PHE   A N   1 
ATOM   50   C CA  . PHE   A 1 8   ? -20.45521 -11.18782 -22.18874 1.000 24.31276 ?  8   PHE   A CA  1 
ATOM   51   C C   . PHE   A 1 8   ? -21.53141 -12.25684 -22.05262 1.000 25.70345 ?  8   PHE   A C   1 
ATOM   52   O O   . PHE   A 1 8   ? -21.62015 -12.92374 -21.02744 1.000 24.21900 ?  8   PHE   A O   1 
ATOM   53   C CB  . PHE   A 1 8   ? -19.23419 -11.79546 -22.87416 1.000 25.05375 ?  8   PHE   A CB  1 
ATOM   54   C CG  . PHE   A 1 8   ? -18.26524 -10.77681 -23.38121 1.000 29.15892 ?  8   PHE   A CG  1 
ATOM   55   C CD1 . PHE   A 1 8   ? -18.50219 -10.13157 -24.57803 1.000 33.39324 ?  8   PHE   A CD1 1 
ATOM   56   C CD2 . PHE   A 1 8   ? -17.13257 -10.46100 -22.66306 1.000 30.38870 ?  8   PHE   A CD2 1 
ATOM   57   C CE1 . PHE   A 1 8   ? -17.61057 -9.17236  -25.05426 1.000 35.74700 ?  8   PHE   A CE1 1 
ATOM   58   C CE2 . PHE   A 1 8   ? -16.24460 -9.50436  -23.13853 1.000 33.84767 ?  8   PHE   A CE2 1 
ATOM   59   C CZ  . PHE   A 1 8   ? -16.48924 -8.87309  -24.33762 1.000 30.70862 ?  8   PHE   A CZ  1 
ATOM   60   N N   . PRO   A 1 9   ? -22.37139 -12.44058 -23.07895 1.000 23.21760 ?  9   PRO   A N   1 
ATOM   61   C CA  . PRO   A 1 9   ? -23.28907 -13.58573 -23.06680 1.000 24.24637 ?  9   PRO   A CA  1 
ATOM   62   C C   . PRO   A 1 9   ? -22.46362 -14.85663 -22.91299 1.000 22.68540 ?  9   PRO   A C   1 
ATOM   63   O O   . PRO   A 1 9   ? -21.43527 -15.01748 -23.56071 1.000 26.52036 ?  9   PRO   A O   1 
ATOM   64   C CB  . PRO   A 1 9   ? -23.99284 -13.49987 -24.43087 1.000 26.66079 ?  9   PRO   A CB  1 
ATOM   65   C CG  . PRO   A 1 9   ? -23.77892 -12.08394 -24.89616 1.000 27.80107 ?  9   PRO   A CG  1 
ATOM   66   C CD  . PRO   A 1 9   ? -22.47062 -11.62957 -24.30667 1.000 26.62227 ?  9   PRO   A CD  1 
ATOM   67   N N   . SER   A 1 10  ? -22.89240 -15.73085 -22.02246 1.000 23.99622 ?  10  SER   A N   1 
ATOM   68   C CA  . SER   A 1 10  ? -22.03777 -16.83452 -21.59289 1.000 24.55485 ?  10  SER   A CA  1 
ATOM   69   C C   . SER   A 1 10  ? -22.28882 -18.13410 -22.34889 1.000 24.71174 ?  10  SER   A C   1 
ATOM   70   O O   . SER   A 1 10  ? -21.59324 -19.11659 -22.08299 1.000 22.76141 ?  10  SER   A O   1 
ATOM   71   C CB  . SER   A 1 10  ? -22.20832 -17.07550 -20.09375 1.000 23.04415 ?  10  SER   A CB  1 
ATOM   72   O OG  . SER   A 1 10  ? -23.54615 -17.33444 -19.74162 1.000 25.31550 ?  10  SER   A OG  1 
ATOM   73   N N   . GLY   A 1 11  ? -23.23419 -18.16124 -23.28951 1.000 24.15276 ?  11  GLY   A N   1 
ATOM   74   C CA  . GLY   A 1 11  ? -23.67330 -19.44174 -23.84544 1.000 26.61463 ?  11  GLY   A CA  1 
ATOM   75   C C   . GLY   A 1 11  ? -22.55915 -20.23498 -24.51793 1.000 25.66390 ?  11  GLY   A C   1 
ATOM   76   O O   . GLY   A 1 11  ? -22.48029 -21.46793 -24.38172 1.000 26.39431 ?  11  GLY   A O   1 
ATOM   77   N N   . LYS   A 1 12  ? -21.70184 -19.54767 -25.27514 1.000 25.46008 ?  12  LYS   A N   1 
ATOM   78   C CA  . LYS   A 1 12  ? -20.62168 -20.24208 -25.96346 1.000 27.76101 ?  12  LYS   A CA  1 
ATOM   79   C C   . LYS   A 1 12  ? -19.69287 -20.93670 -24.97768 1.000 26.75864 ?  12  LYS   A C   1 
ATOM   80   O O   . LYS   A 1 12  ? -19.14783 -22.00429 -25.29033 1.000 27.32885 ?  12  LYS   A O   1 
ATOM   81   C CB  . LYS   A 1 12  ? -19.83059 -19.26994 -26.84434 1.000 27.64796 ?  12  LYS   A CB  1 
ATOM   82   C CG  . LYS   A 1 12  ? -20.56561 -18.74295 -28.04508 1.000 31.32271 ?  12  LYS   A CG  1 
ATOM   83   C CD  . LYS   A 1 12  ? -19.73124 -17.66516 -28.74299 1.000 37.57423 ?  12  LYS   A CD  1 
ATOM   84   C CE  . LYS   A 1 12  ? -20.15891 -17.46822 -30.19835 1.000 42.19994 ?  12  LYS   A CE  1 
ATOM   85   N NZ  . LYS   A 1 12  ? -21.62043 -17.18133 -30.35046 1.000 47.33661 ?  12  LYS   A NZ  1 
ATOM   86   N N   . VAL   A 1 13  ? -19.51603 -20.36901 -23.78184 1.000 22.68725 ?  13  VAL   A N   1 
ATOM   87   C CA  . VAL   A 1 13  ? -18.64673 -20.99338 -22.78291 1.000 23.67050 ?  13  VAL   A CA  1 
ATOM   88   C C   . VAL   A 1 13  ? -19.39907 -22.07014 -22.00631 1.000 23.13651 ?  13  VAL   A C   1 
ATOM   89   O O   . VAL   A 1 13  ? -18.83619 -23.13064 -21.69225 1.000 21.36957 ?  13  VAL   A O   1 
ATOM   90   C CB  . VAL   A 1 13  ? -18.06385 -19.92093 -21.84295 1.000 21.67917 ?  13  VAL   A CB  1 
ATOM   91   C CG1 . VAL   A 1 13  ? -17.09814 -20.55500 -20.80345 1.000 22.87122 ?  13  VAL   A CG1 1 
ATOM   92   C CG2 . VAL   A 1 13  ? -17.32668 -18.86730 -22.64686 1.000 24.13098 ?  13  VAL   A CG2 1 
ATOM   93   N N   . GLU   A 1 14  ? -20.66764 -21.80836 -21.66915 1.000 22.67252 ?  14  GLU   A N   1 
ATOM   94   C CA  . GLU   A 1 14  ? -21.49694 -22.82350 -21.01627 1.000 23.86936 ?  14  GLU   A CA  1 
ATOM   95   C C   . GLU   A 1 14  ? -21.43901 -24.15405 -21.74959 1.000 24.14334 ?  14  GLU   A C   1 
ATOM   96   O O   . GLU   A 1 14  ? -21.33216 -25.20978 -21.11596 1.000 23.49026 ?  14  GLU   A O   1 
ATOM   97   C CB  . GLU   A 1 14  ? -22.95417 -22.38164 -20.94125 1.000 25.70792 ?  14  GLU   A CB  1 
ATOM   98   C CG  . GLU   A 1 14  ? -23.24983 -21.28519 -19.94676 1.000 23.93081 ?  14  GLU   A CG  1 
ATOM   99   C CD  . GLU   A 1 14  ? -24.64389 -20.72801 -20.19844 1.000 26.66388 ?  14  GLU   A CD  1 
ATOM   100  O OE1 . GLU   A 1 14  ? -25.62485 -21.49373 -20.09506 1.000 30.12108 ?  14  GLU   A OE1 1 
ATOM   101  O OE2 . GLU   A 1 14  ? -24.74577 -19.54162 -20.55153 1.000 28.25076 -1 14  GLU   A OE2 1 
ATOM   102  N N   . GLY   A 1 15  ? -21.47922 -24.11591 -23.08425 1.000 24.62451 ?  15  GLY   A N   1 
ATOM   103  C CA  . GLY   A 1 15  ? -21.41226 -25.33904 -23.86333 1.000 25.94866 ?  15  GLY   A CA  1 
ATOM   104  C C   . GLY   A 1 15  ? -20.07480 -26.07236 -23.81470 1.000 25.52716 ?  15  GLY   A C   1 
ATOM   105  O O   . GLY   A 1 15  ? -19.95177 -27.14246 -24.41783 1.000 25.99073 ?  15  GLY   A O   1 
ATOM   106  N N   . CYS   A 1 16  ? -19.09203 -25.53451 -23.09745 1.000 21.33993 ?  16  CYS   A N   1 
ATOM   107  C CA  . CYS   A 1 16  ? -17.75736 -26.10755 -22.98185 1.000 19.70262 ?  16  CYS   A CA  1 
ATOM   108  C C   . CYS   A 1 16  ? -17.44154 -26.58742 -21.58193 1.000 21.89659 ?  16  CYS   A C   1 
ATOM   109  O O   . CYS   A 1 16  ? -16.36693 -27.14301 -21.36636 1.000 22.63420 ?  16  CYS   A O   1 
ATOM   110  C CB  . CYS   A 1 16  ? -16.69291 -25.08784 -23.39505 1.000 21.23061 ?  16  CYS   A CB  1 
ATOM   111  S SG  . CYS   A 1 16  ? -16.93890 -24.62115 -25.14457 1.000 27.10776 ?  16  CYS   A SG  1 
ATOM   112  N N   . MET   A 1 17  ? -18.32883 -26.39373 -20.61826 1.000 19.88742 ?  17  MET   A N   1 
ATOM   113  C CA  . MET   A 1 17  ? -17.96907 -26.71853 -19.23928 1.000 20.86506 ?  17  MET   A CA  1 
ATOM   114  C C   . MET   A 1 17  ? -18.25452 -28.18360 -18.94441 1.000 21.30753 ?  17  MET   A C   1 
ATOM   115  O O   . MET   A 1 17  ? -19.33020 -28.69439 -19.28447 1.000 23.52596 ?  17  MET   A O   1 
ATOM   116  C CB  . MET   A 1 17  ? -18.72728 -25.82283 -18.25892 1.000 21.47297 ?  17  MET   A CB  1 
ATOM   117  C CG  . MET   A 1 17  ? -18.34630 -24.34411 -18.38201 1.000 24.98154 ?  17  MET   A CG  1 
ATOM   118  S SD  . MET   A 1 17  ? -16.59541 -23.95792 -18.43990 1.000 24.56128 ?  17  MET   A SD  1 
ATOM   119  C CE  . MET   A 1 17  ? -15.98558 -24.69354 -16.90471 1.000 23.26294 ?  17  MET   A CE  1 
ATOM   120  N N   . VAL   A 1 18  ? -17.29951 -28.85018 -18.29877 1.000 21.30145 ?  18  VAL   A N   1 
ATOM   121  C CA  . VAL   A 1 18  ? -17.46397 -30.23507 -17.85610 1.000 20.48123 ?  18  VAL   A CA  1 
ATOM   122  C C   . VAL   A 1 18  ? -16.96032 -30.36418 -16.42405 1.000 21.95005 ?  18  VAL   A C   1 
ATOM   123  O O   . VAL   A 1 18  ? -16.40906 -29.42646 -15.84060 1.000 20.74238 ?  18  VAL   A O   1 
ATOM   124  C CB  . VAL   A 1 18  ? -16.73647 -31.23436 -18.79270 1.000 21.21671 ?  18  VAL   A CB  1 
ATOM   125  C CG1 . VAL   A 1 18  ? -17.37540 -31.19736 -20.19833 1.000 21.41175 ?  18  VAL   A CG1 1 
ATOM   126  C CG2 . VAL   A 1 18  ? -15.26275 -30.93115 -18.84600 1.000 21.55211 ?  18  VAL   A CG2 1 
ATOM   127  N N   . GLN   A 1 19  ? -17.14307 -31.55637 -15.86230 1.000 21.87061 ?  19  GLN   A N   1 
ATOM   128  C CA  . GLN   A 1 19  ? -16.67678 -31.90109 -14.52550 1.000 21.73771 ?  19  GLN   A CA  1 
ATOM   129  C C   . GLN   A 1 19  ? -15.51845 -32.87872 -14.66898 1.000 20.88315 ?  19  GLN   A C   1 
ATOM   130  O O   . GLN   A 1 19  ? -15.56582 -33.77967 -15.52065 1.000 23.98338 ?  19  GLN   A O   1 
ATOM   131  C CB  . GLN   A 1 19  ? -17.83933 -32.52911 -13.73322 1.000 26.45392 ?  19  GLN   A CB  1 
ATOM   132  C CG  . GLN   A 1 19  ? -17.71718 -32.56647 -12.22902 1.000 31.27855 ?  19  GLN   A CG  1 
ATOM   133  C CD  . GLN   A 1 19  ? -18.93554 -33.23020 -11.57300 1.000 28.10733 ?  19  GLN   A CD  1 
ATOM   134  O OE1 . GLN   A 1 19  ? -19.00606 -33.34074 -10.35614 1.000 41.01264 ?  19  GLN   A OE1 1 
ATOM   135  N NE2 . GLN   A 1 19  ? -19.88814 -33.66507 -12.38433 1.000 37.58659 ?  19  GLN   A NE2 1 
ATOM   136  N N   . VAL   A 1 20  ? -14.47353 -32.71214 -13.84748 1.000 20.84605 ?  20  VAL   A N   1 
ATOM   137  C CA  . VAL   A 1 20  ? -13.33214 -33.62440 -13.81325 1.000 21.84903 ?  20  VAL   A CA  1 
ATOM   138  C C   . VAL   A 1 20  ? -13.15528 -34.09420 -12.37395 1.000 20.73228 ?  20  VAL   A C   1 
ATOM   139  O O   . VAL   A 1 20  ? -13.07887 -33.27486 -11.45605 1.000 22.78767 ?  20  VAL   A O   1 
ATOM   140  C CB  . VAL   A 1 20  ? -12.03478 -32.94972 -14.31185 1.000 23.88085 ?  20  VAL   A CB  1 
ATOM   141  C CG1 . VAL   A 1 20  ? -10.87532 -33.94579 -14.36449 1.000 22.67720 ?  20  VAL   A CG1 1 
ATOM   142  C CG2 . VAL   A 1 20  ? -12.24583 -32.35618 -15.67396 1.000 20.56044 ?  20  VAL   A CG2 1 
ATOM   143  N N   . THR   A 1 21  ? -13.06419 -35.40668 -12.18808 1.000 22.40966 ?  21  THR   A N   1 
ATOM   144  C CA  . THR   A 1 21  ? -12.87276 -35.98753 -10.86987 1.000 25.82751 ?  21  THR   A CA  1 
ATOM   145  C C   . THR   A 1 21  ? -11.70879 -36.96137 -10.89718 1.000 24.19266 ?  21  THR   A C   1 
ATOM   146  O O   . THR   A 1 21  ? -11.53185 -37.72099 -11.85942 1.000 23.28164 ?  21  THR   A O   1 
ATOM   147  C CB  . THR   A 1 21  ? -14.15005 -36.72002 -10.39594 1.000 26.37948 ?  21  THR   A CB  1 
ATOM   148  O OG1 . THR   A 1 21  ? -15.22908 -35.79083 -10.31435 1.000 26.72721 ?  21  THR   A OG1 1 
ATOM   149  C CG2 . THR   A 1 21  ? -13.94990 -37.33125 -8.99315  1.000 27.74750 ?  21  THR   A CG2 1 
ATOM   150  N N   . CYS   A 1 22  ? -10.91999 -36.90458 -9.82790  1.000 23.12526 ?  22  CYS   A N   1 
ATOM   151  C CA  A CYS   A 1 22  ? -9.89559  -37.89561 -9.55757  0.648 27.94077 ?  22  CYS   A CA  1 
ATOM   152  C CA  B CYS   A 1 22  ? -9.85810  -37.85892 -9.52679  0.352 28.87026 ?  22  CYS   A CA  1 
ATOM   153  C C   . CYS   A 1 22  ? -10.04726 -38.29166 -8.09343  1.000 30.36484 ?  22  CYS   A C   1 
ATOM   154  O O   . CYS   A 1 22  ? -9.95862  -37.44585 -7.19537  1.000 30.05011 ?  22  CYS   A O   1 
ATOM   155  C CB  A CYS   A 1 22  ? -8.50417  -37.34379 -9.88744  0.648 30.04933 ?  22  CYS   A CB  1 
ATOM   156  C CB  B CYS   A 1 22  ? -8.48033  -37.22838 -9.64421  0.352 30.26170 ?  22  CYS   A CB  1 
ATOM   157  S SG  A CYS   A 1 22  ? -7.18566  -38.57666 -10.08235 0.648 32.28010 ?  22  CYS   A SG  1 
ATOM   158  S SG  B CYS   A 1 22  ? -7.87195  -37.14593 -11.23807 0.352 27.74444 ?  22  CYS   A SG  1 
ATOM   159  N N   . GLY   A 1 23  ? -10.31479 -39.57663 -7.86783  1.000 32.21626 ?  23  GLY   A N   1 
ATOM   160  C CA  . GLY   A 1 23  ? -10.61915 -40.01117 -6.50885  1.000 32.20373 ?  23  GLY   A CA  1 
ATOM   161  C C   . GLY   A 1 23  ? -11.88004 -39.33068 -6.02816  1.000 30.39345 ?  23  GLY   A C   1 
ATOM   162  O O   . GLY   A 1 23  ? -12.94993 -39.45707 -6.63503  1.000 33.39461 ?  23  GLY   A O   1 
ATOM   163  N N   . THR   A 1 24  ? -11.76935 -38.56696 -4.94030  1.000 33.15691 ?  24  THR   A N   1 
ATOM   164  C CA  . THR   A 1 24  ? -12.87698 -37.75107 -4.46009  1.000 34.10117 ?  24  THR   A CA  1 
ATOM   165  C C   . THR   A 1 24  ? -12.69460 -36.26515 -4.74915  1.000 35.45561 ?  24  THR   A C   1 
ATOM   166  O O   . THR   A 1 24  ? -13.53206 -35.45816 -4.32862  1.000 37.22734 ?  24  THR   A O   1 
ATOM   167  C CB  . THR   A 1 24  ? -13.08088 -37.96265 -2.95239  1.000 37.10856 ?  24  THR   A CB  1 
ATOM   168  O OG1 . THR   A 1 24  ? -11.90542 -37.55249 -2.24093  1.000 42.84462 ?  24  THR   A OG1 1 
ATOM   169  C CG2 . THR   A 1 24  ? -13.34565 -39.43253 -2.66997  1.000 36.93759 ?  24  THR   A CG2 1 
ATOM   170  N N   . THR   A 1 25  ? -11.63413 -35.87359 -5.45098  1.000 31.82242 ?  25  THR   A N   1 
ATOM   171  C CA  . THR   A 1 25  ? -11.40635 -34.46873 -5.77077  1.000 29.34570 ?  25  THR   A CA  1 
ATOM   172  C C   . THR   A 1 25  ? -12.12657 -34.14695 -7.07601  1.000 29.57361 ?  25  THR   A C   1 
ATOM   173  O O   . THR   A 1 25  ? -11.87186 -34.79218 -8.09288  1.000 27.65390 ?  25  THR   A O   1 
ATOM   174  C CB  . THR   A 1 25  ? -9.91137  -34.17152 -5.88702  1.000 31.92725 ?  25  THR   A CB  1 
ATOM   175  O OG1 . THR   A 1 25  ? -9.23718  -34.63510 -4.70443  1.000 34.45469 ?  25  THR   A OG1 1 
ATOM   176  C CG2 . THR   A 1 25  ? -9.65776  -32.66213 -6.04076  1.000 31.14682 ?  25  THR   A CG2 1 
ATOM   177  N N   . THR   A 1 26  ? -13.02175 -33.16121 -7.04479  1.000 26.47224 ?  26  THR   A N   1 
ATOM   178  C CA  . THR   A 1 26  ? -13.79190 -32.78770 -8.22402  1.000 26.15909 ?  26  THR   A CA  1 
ATOM   179  C C   . THR   A 1 26  ? -13.66374 -31.29298 -8.48715  1.000 24.83282 ?  26  THR   A C   1 
ATOM   180  O O   . THR   A 1 26  ? -13.74107 -30.47683 -7.56291  1.000 27.26510 ?  26  THR   A O   1 
ATOM   181  C CB  . THR   A 1 26  ? -15.28886 -33.15097 -8.06825  1.000 31.36855 ?  26  THR   A CB  1 
ATOM   182  O OG1 . THR   A 1 26  ? -15.44757 -34.57074 -8.01215  1.000 33.07374 ?  26  THR   A OG1 1 
ATOM   183  C CG2 . THR   A 1 26  ? -16.09252 -32.65516 -9.26189  1.000 30.25483 ?  26  THR   A CG2 1 
ATOM   184  N N   . LEU   A 1 27  ? -13.53222 -30.92964 -9.75622  1.000 24.33253 ?  27  LEU   A N   1 
ATOM   185  C CA  . LEU   A 1 27  ? -13.56381 -29.50751 -10.12621 1.000 20.69371 ?  27  LEU   A CA  1 
ATOM   186  C C   . LEU   A 1 27  ? -14.08479 -29.42064 -11.55109 1.000 21.96062 ?  27  LEU   A C   1 
ATOM   187  O O   . LEU   A 1 27  ? -14.59723 -30.40213 -12.09725 1.000 22.50910 ?  27  LEU   A O   1 
ATOM   188  C CB  . LEU   A 1 27  ? -12.18973 -28.85982 -9.93450  1.000 22.92006 ?  27  LEU   A CB  1 
ATOM   189  C CG  . LEU   A 1 27  ? -10.91169 -29.63420 -10.32135 1.000 22.63298 ?  27  LEU   A CG  1 
ATOM   190  C CD1 . LEU   A 1 27  ? -10.87720 -29.93157 -11.82313 1.000 22.93415 ?  27  LEU   A CD1 1 
ATOM   191  C CD2 . LEU   A 1 27  ? -9.70967  -28.83365 -9.94920  1.000 24.43892 ?  27  LEU   A CD2 1 
ATOM   192  N N   . ASN   A 1 28  ? -13.98878 -28.22203 -12.14743 1.000 20.35059 ?  28  ASN   A N   1 
ATOM   193  C CA  . ASN   A 1 28  ? -14.45635 -27.97281 -13.49955 1.000 19.97400 ?  28  ASN   A CA  1 
ATOM   194  C C   . ASN   A 1 28  ? -13.33036 -28.06646 -14.51712 1.000 19.71247 ?  28  ASN   A C   1 
ATOM   195  O O   . ASN   A 1 28  ? -12.16951 -27.75382 -14.22164 1.000 22.39935 ?  28  ASN   A O   1 
ATOM   196  C CB  . ASN   A 1 28  ? -15.07710 -26.57172 -13.56689 1.000 20.68495 ?  28  ASN   A CB  1 
ATOM   197  C CG  . ASN   A 1 28  ? -16.11886 -26.37909 -12.50588 1.000 22.65497 ?  28  ASN   A CG  1 
ATOM   198  O OD1 . ASN   A 1 28  ? -17.21229 -26.88865 -12.62931 1.000 24.48287 ?  28  ASN   A OD1 1 
ATOM   199  N ND2 . ASN   A 1 28  ? -15.79071 -25.61961 -11.46851 1.000 24.11268 ?  28  ASN   A ND2 1 
ATOM   200  N N   . GLY   A 1 29  ? -13.71535 -28.43864 -15.74048 1.000 20.49856 ?  29  GLY   A N   1 
ATOM   201  C CA  . GLY   A 1 29  ? -12.81759 -28.38732 -16.87639 1.000 19.40927 ?  29  GLY   A CA  1 
ATOM   202  C C   . GLY   A 1 29  ? -13.47790 -27.75315 -18.08252 1.000 20.59295 ?  29  GLY   A C   1 
ATOM   203  O O   . GLY   A 1 29  ? -14.69597 -27.61736 -18.16449 1.000 21.18595 ?  29  GLY   A O   1 
ATOM   204  N N   . LEU   A 1 30  ? -12.63352 -27.39758 -19.05353 1.000 20.10021 ?  30  LEU   A N   1 
ATOM   205  C CA  . LEU   A 1 30  ? -13.03720 -26.69746 -20.26709 1.000 21.25046 ?  30  LEU   A CA  1 
ATOM   206  C C   . LEU   A 1 30  ? -12.84047 -27.63947 -21.45266 1.000 20.82055 ?  30  LEU   A C   1 
ATOM   207  O O   . LEU   A 1 30  ? -11.70744 -28.00134 -21.76537 1.000 21.03170 ?  30  LEU   A O   1 
ATOM   208  C CB  . LEU   A 1 30  ? -12.21398 -25.41144 -20.43788 1.000 23.58579 ?  30  LEU   A CB  1 
ATOM   209  C CG  . LEU   A 1 30  ? -12.57273 -24.49010 -21.61078 1.000 20.63517 ?  30  LEU   A CG  1 
ATOM   210  C CD1 . LEU   A 1 30  ? -13.92019 -23.83294 -21.35516 1.000 22.02994 ?  30  LEU   A CD1 1 
ATOM   211  C CD2 . LEU   A 1 30  ? -11.47173 -23.45013 -21.72267 1.000 22.71834 ?  30  LEU   A CD2 1 
ATOM   212  N N   . TRP   A 1 31  ? -13.92493 -27.99313 -22.12697 1.000 20.50186 ?  31  TRP   A N   1 
ATOM   213  C CA  . TRP   A 1 31  ? -13.89757 -28.99949 -23.19307 1.000 21.43822 ?  31  TRP   A CA  1 
ATOM   214  C C   . TRP   A 1 31  ? -13.94579 -28.27862 -24.53943 1.000 21.03094 ?  31  TRP   A C   1 
ATOM   215  O O   . TRP   A 1 31  ? -14.98960 -27.75616 -24.93783 1.000 21.37511 ?  31  TRP   A O   1 
ATOM   216  C CB  . TRP   A 1 31  ? -15.07331 -29.95876 -23.01981 1.000 20.82299 ?  31  TRP   A CB  1 
ATOM   217  C CG  . TRP   A 1 31  ? -15.23851 -31.07652 -24.04143 1.000 20.65058 ?  31  TRP   A CG  1 
ATOM   218  C CD1 . TRP   A 1 31  ? -14.27885 -31.65381 -24.84882 1.000 21.48293 ?  31  TRP   A CD1 1 
ATOM   219  C CD2 . TRP   A 1 31  ? -16.46942 -31.72788 -24.35044 1.000 21.68275 ?  31  TRP   A CD2 1 
ATOM   220  N NE1 . TRP   A 1 31  ? -14.86428 -32.64550 -25.63159 1.000 22.54877 ?  31  TRP   A NE1 1 
ATOM   221  C CE2 . TRP   A 1 31  ? -16.20139 -32.71028 -25.33632 1.000 22.93645 ?  31  TRP   A CE2 1 
ATOM   222  C CE3 . TRP   A 1 31  ? -17.77263 -31.58834 -23.87471 1.000 23.80911 ?  31  TRP   A CE3 1 
ATOM   223  C CZ2 . TRP   A 1 31  ? -17.19750 -33.52579 -25.86432 1.000 24.68043 ?  31  TRP   A CZ2 1 
ATOM   224  C CZ3 . TRP   A 1 31  ? -18.75816 -32.40018 -24.39938 1.000 25.18873 ?  31  TRP   A CZ3 1 
ATOM   225  C CH2 . TRP   A 1 31  ? -18.46763 -33.35664 -25.38440 1.000 24.74200 ?  31  TRP   A CH2 1 
ATOM   226  N N   . LEU   A 1 32  ? -12.82197 -28.29366 -25.25554 1.000 22.17400 ?  32  LEU   A N   1 
ATOM   227  C CA  . LEU   A 1 32  ? -12.70538 -27.64658 -26.55196 1.000 21.53842 ?  32  LEU   A CA  1 
ATOM   228  C C   . LEU   A 1 32  ? -12.15190 -28.66511 -27.53660 1.000 23.61996 ?  32  LEU   A C   1 
ATOM   229  O O   . LEU   A 1 32  ? -11.09950 -29.25754 -27.28284 1.000 23.70697 ?  32  LEU   A O   1 
ATOM   230  C CB  . LEU   A 1 32  ? -11.78236 -26.41927 -26.46024 1.000 25.38869 ?  32  LEU   A CB  1 
ATOM   231  C CG  . LEU   A 1 32  ? -12.26909 -25.30236 -25.53250 1.000 24.31365 ?  32  LEU   A CG  1 
ATOM   232  C CD1 . LEU   A 1 32  ? -11.13553 -24.29656 -25.30837 1.000 23.47045 ?  32  LEU   A CD1 1 
ATOM   233  C CD2 . LEU   A 1 32  ? -13.43811 -24.58948 -26.17463 1.000 24.43714 ?  32  LEU   A CD2 1 
ATOM   234  N N   . ASP   A 1 33  ? -12.86648 -28.87231 -28.63839 1.000 24.34267 ?  33  ASP   A N   1 
ATOM   235  C CA  . ASP   A 1 33  ? -12.52177 -29.95474 -29.57049 1.000 25.68580 ?  33  ASP   A CA  1 
ATOM   236  C C   . ASP   A 1 33  ? -12.44978 -31.24684 -28.75880 1.000 24.45119 ?  33  ASP   A C   1 
ATOM   237  O O   . ASP   A 1 33  ? -13.39739 -31.55189 -28.00957 1.000 24.28164 ?  33  ASP   A O   1 
ATOM   238  C CB  . ASP   A 1 33  ? -11.24067 -29.54718 -30.30010 1.000 26.91188 ?  33  ASP   A CB  1 
ATOM   239  C CG  . ASP   A 1 33  ? -11.46354 -28.36059 -31.22931 1.000 30.15839 ?  33  ASP   A CG  1 
ATOM   240  O OD1 . ASP   A 1 33  ? -12.52482 -28.31344 -31.88765 1.000 31.74595 ?  33  ASP   A OD1 1 
ATOM   241  O OD2 . ASP   A 1 33  ? -10.59044 -27.46264 -31.28148 1.000 32.33633 -1 33  ASP   A OD2 1 
ATOM   242  N N   . ASP   A 1 34  ? -11.36254 -32.02237 -28.83591 1.000 25.11085 ?  34  ASP   A N   1 
ATOM   243  C CA  . ASP   A 1 34  ? -11.26502 -33.28600 -28.12070 1.000 24.94106 ?  34  ASP   A CA  1 
ATOM   244  C C   . ASP   A 1 34  ? -10.31321 -33.20780 -26.92717 1.000 23.35119 ?  34  ASP   A C   1 
ATOM   245  O O   . ASP   A 1 34  ? -9.71880  -34.21804 -26.52088 1.000 26.26853 ?  34  ASP   A O   1 
ATOM   246  C CB  . ASP   A 1 34  ? -10.85755 -34.40690 -29.08801 1.000 29.63883 ?  34  ASP   A CB  1 
ATOM   247  C CG  . ASP   A 1 34  ? -9.46342  -34.21291 -29.67547 1.000 34.65035 ?  34  ASP   A CG  1 
ATOM   248  O OD1 . ASP   A 1 34  ? -8.93040  -33.08141 -29.63088 1.000 34.44424 ?  34  ASP   A OD1 1 
ATOM   249  O OD2 . ASP   A 1 34  ? -8.89792  -35.20229 -30.21133 1.000 39.36570 -1 34  ASP   A OD2 1 
ATOM   250  N N   . VAL   A 1 35  ? -10.16866 -32.01902 -26.31815 1.000 23.26622 ?  35  VAL   A N   1 
ATOM   251  C CA  . VAL   A 1 35  ? -9.27997  -31.85237 -25.17417 1.000 23.65786 ?  35  VAL   A CA  1 
ATOM   252  C C   . VAL   A 1 35  ? -10.06013 -31.17368 -24.05943 1.000 22.96439 ?  35  VAL   A C   1 
ATOM   253  O O   . VAL   A 1 35  ? -10.83064 -30.24336 -24.31295 1.000 21.76015 ?  35  VAL   A O   1 
ATOM   254  C CB  . VAL   A 1 35  ? -8.02727  -31.01838 -25.52971 1.000 23.30602 ?  35  VAL   A CB  1 
ATOM   255  C CG1 . VAL   A 1 35  ? -7.13005  -30.81629 -24.29054 1.000 23.45445 ?  35  VAL   A CG1 1 
ATOM   256  C CG2 . VAL   A 1 35  ? -7.21776  -31.72588 -26.61515 1.000 27.49958 ?  35  VAL   A CG2 1 
ATOM   257  N N   . VAL   A 1 36  ? -9.83049  -31.61709 -22.82540 1.000 22.43713 ?  36  VAL   A N   1 
ATOM   258  C CA  . VAL   A 1 36  ? -10.41125 -31.01349 -21.63783 1.000 22.21638 ?  36  VAL   A CA  1 
ATOM   259  C C   . VAL   A 1 36  ? -9.26827  -30.41096 -20.83392 1.000 21.55907 ?  36  VAL   A C   1 
ATOM   260  O O   . VAL   A 1 36  ? -8.27498  -31.08271 -20.54758 1.000 22.62696 ?  36  VAL   A O   1 
ATOM   261  C CB  . VAL   A 1 36  ? -11.20362 -32.04396 -20.80634 1.000 20.74168 ?  36  VAL   A CB  1 
ATOM   262  C CG1 . VAL   A 1 36  ? -11.63257 -31.40687 -19.47841 1.000 22.22302 ?  36  VAL   A CG1 1 
ATOM   263  C CG2 . VAL   A 1 36  ? -12.42525 -32.50901 -21.58227 1.000 23.38792 ?  36  VAL   A CG2 1 
ATOM   264  N N   . TYR   A 1 37  ? -9.39583  -29.13381 -20.48357 1.000 22.33475 ?  37  TYR   A N   1 
ATOM   265  C CA  . TYR   A 1 37  ? -8.36910  -28.42414 -19.73098 1.000 20.26326 ?  37  TYR   A CA  1 
ATOM   266  C C   . TYR   A 1 37  ? -8.84610  -28.17050 -18.30249 1.000 23.73667 ?  37  TYR   A C   1 
ATOM   267  O O   . TYR   A 1 37  ? -9.97670  -27.73917 -18.11088 1.000 22.58999 ?  37  TYR   A O   1 
ATOM   268  C CB  . TYR   A 1 37  ? -8.05007  -27.06253 -20.39740 1.000 20.92107 ?  37  TYR   A CB  1 
ATOM   269  C CG  . TYR   A 1 37  ? -7.66664  -27.14262 -21.86647 1.000 20.34833 ?  37  TYR   A CG  1 
ATOM   270  C CD1 . TYR   A 1 37  ? -8.63230  -27.29051 -22.84778 1.000 22.47062 ?  37  TYR   A CD1 1 
ATOM   271  C CD2 . TYR   A 1 37  ? -6.33448  -27.07132 -22.26487 1.000 27.53334 ?  37  TYR   A CD2 1 
ATOM   272  C CE1 . TYR   A 1 37  ? -8.28113  -27.40214 -24.18536 1.000 24.67300 ?  37  TYR   A CE1 1 
ATOM   273  C CE2 . TYR   A 1 37  ? -5.97657  -27.15971 -23.59843 1.000 28.21568 ?  37  TYR   A CE2 1 
ATOM   274  C CZ  . TYR   A 1 37  ? -6.95349  -27.33123 -24.55263 1.000 25.85480 ?  37  TYR   A CZ  1 
ATOM   275  O OH  . TYR   A 1 37  ? -6.61815  -27.43695 -25.89790 1.000 27.17477 ?  37  TYR   A OH  1 
ATOM   276  N N   . CYS   A 1 38  ? -8.00620  -28.41541 -17.29374 1.000 23.03182 ?  38  CYS   A N   1 
ATOM   277  C CA  . CYS   A 1 38  ? -8.46924  -28.20846 -15.91907 1.000 21.56123 ?  38  CYS   A CA  1 
ATOM   278  C C   . CYS   A 1 38  ? -7.25924  -27.99325 -15.00450 1.000 23.91548 ?  38  CYS   A C   1 
ATOM   279  O O   . CYS   A 1 38  ? -6.12331  -28.26760 -15.40059 1.000 24.76708 ?  38  CYS   A O   1 
ATOM   280  C CB  . CYS   A 1 38  ? -9.31981  -29.39878 -15.42922 1.000 21.86140 ?  38  CYS   A CB  1 
ATOM   281  S SG  . CYS   A 1 38  ? -8.34805  -30.89301 -15.02237 1.000 25.66210 ?  38  CYS   A SG  1 
ATOM   282  N N   . PRO   A 1 39  ? -7.46979  -27.51055 -13.77308 1.000 22.49390 ?  39  PRO   A N   1 
ATOM   283  C CA  . PRO   A 1 39  ? -6.32082  -27.30087 -12.87082 1.000 19.31767 ?  39  PRO   A CA  1 
ATOM   284  C C   . PRO   A 1 39  ? -5.67030  -28.62666 -12.49068 1.000 23.54682 ?  39  PRO   A C   1 
ATOM   285  O O   . PRO   A 1 39  ? -6.35344  -29.61405 -12.23867 1.000 22.84491 ?  39  PRO   A O   1 
ATOM   286  C CB  . PRO   A 1 39  ? -6.94401  -26.62010 -11.64703 1.000 22.61928 ?  39  PRO   A CB  1 
ATOM   287  C CG  . PRO   A 1 39  ? -8.17529  -25.93870 -12.20075 1.000 20.14603 ?  39  PRO   A CG  1 
ATOM   288  C CD  . PRO   A 1 39  ? -8.71199  -26.95846 -13.18891 1.000 20.67504 ?  39  PRO   A CD  1 
ATOM   289  N N   . ARG   A 1 40  ? -4.33825  -28.64230 -12.42755 1.000 24.23692 ?  40  ARG   A N   1 
ATOM   290  C CA  . ARG   A 1 40  ? -3.68929  -29.92967 -12.15502 1.000 26.09832 ?  40  ARG   A CA  1 
ATOM   291  C C   . ARG   A 1 40  ? -3.91357  -30.43446 -10.72985 1.000 26.26337 ?  40  ARG   A C   1 
ATOM   292  O O   . ARG   A 1 40  ? -3.77464  -31.64597 -10.49199 1.000 26.79121 ?  40  ARG   A O   1 
ATOM   293  C CB  . ARG   A 1 40  ? -2.20418  -29.84395 -12.45026 1.000 26.98953 ?  40  ARG   A CB  1 
ATOM   294  C CG  . ARG   A 1 40  ? -1.47856  -28.86108 -11.55881 1.000 23.27256 ?  40  ARG   A CG  1 
ATOM   295  C CD  . ARG   A 1 40  ? -0.03069  -28.87107 -11.89838 1.000 27.59364 ?  40  ARG   A CD  1 
ATOM   296  N NE  . ARG   A 1 40  ? 0.71737   -27.95530 -11.04980 1.000 26.80004 ?  40  ARG   A NE  1 
ATOM   297  C CZ  . ARG   A 1 40  ? 2.03608   -27.87264 -11.05561 1.000 28.25486 ?  40  ARG   A CZ  1 
ATOM   298  N NH1 . ARG   A 1 40  ? 2.76262   -28.61922 -11.86842 1.000 28.28912 ?  40  ARG   A NH1 1 
ATOM   299  N NH2 . ARG   A 1 40  ? 2.63571   -27.04458 -10.20746 1.000 28.03748 ?  40  ARG   A NH2 1 
ATOM   300  N N   . HIS   A 1 41  ? -4.31737  -29.56926 -9.77964  1.000 25.40063 ?  41  HIS   A N   1 
ATOM   301  C CA  . HIS   A 1 41  ? -4.52038  -30.08168 -8.42298  1.000 27.70573 ?  41  HIS   A CA  1 
ATOM   302  C C   . HIS   A 1 41  ? -5.71220  -31.01962 -8.30655  1.000 27.33364 ?  41  HIS   A C   1 
ATOM   303  O O   . HIS   A 1 41  ? -5.92384  -31.59427 -7.22891  1.000 28.47628 ?  41  HIS   A O   1 
ATOM   304  C CB  . HIS   A 1 41  ? -4.61778  -28.94182 -7.38928  1.000 27.58368 ?  41  HIS   A CB  1 
ATOM   305  C CG  . HIS   A 1 41  ? -5.85065  -28.08640 -7.49269  1.000 25.43538 ?  41  HIS   A CG  1 
ATOM   306  N ND1 . HIS   A 1 41  ? -5.82335  -26.81561 -8.01799  1.000 25.66905 ?  41  HIS   A ND1 1 
ATOM   307  C CD2 . HIS   A 1 41  ? -7.12227  -28.29324 -7.07338  1.000 28.46149 ?  41  HIS   A CD2 1 
ATOM   308  C CE1 . HIS   A 1 41  ? -7.02586  -26.27218 -7.92540  1.000 27.76856 ?  41  HIS   A CE1 1 
ATOM   309  N NE2 . HIS   A 1 41  ? -7.83573  -27.14966 -7.36176  1.000 28.10643 ?  41  HIS   A NE2 1 
ATOM   310  N N   . VAL   A 1 42  ? -6.46008  -31.25906 -9.38680  1.000 24.07820 ?  42  VAL   A N   1 
ATOM   311  C CA  . VAL   A 1 42  ? -7.45333  -32.30928 -9.32793  1.000 23.26460 ?  42  VAL   A CA  1 
ATOM   312  C C   . VAL   A 1 42  ? -6.81058  -33.65198 -8.97471  1.000 25.94377 ?  42  VAL   A C   1 
ATOM   313  O O   . VAL   A 1 42  ? -7.49062  -34.51687 -8.42989  1.000 27.71782 ?  42  VAL   A O   1 
ATOM   314  C CB  . VAL   A 1 42  ? -8.25214  -32.40029 -10.64646 1.000 24.21354 ?  42  VAL   A CB  1 
ATOM   315  C CG1 . VAL   A 1 42  ? -7.38236  -32.96224 -11.76727 1.000 24.58418 ?  42  VAL   A CG1 1 
ATOM   316  C CG2 . VAL   A 1 42  ? -9.50898  -33.24222 -10.44163 1.000 24.87024 ?  42  VAL   A CG2 1 
ATOM   317  N N   . ILE   A 1 43  ? -5.50666  -33.83193 -9.22815  1.000 27.01617 ?  43  ILE   A N   1 
ATOM   318  C CA  . ILE   A 1 43  ? -4.89284  -35.13555 -8.92587  1.000 29.77686 ?  43  ILE   A CA  1 
ATOM   319  C C   . ILE   A 1 43  ? -4.49517  -35.29231 -7.46304  1.000 33.86772 ?  43  ILE   A C   1 
ATOM   320  O O   . ILE   A 1 43  ? -3.94470  -36.34804 -7.08971  1.000 35.97352 ?  43  ILE   A O   1 
ATOM   321  C CB  . ILE   A 1 43  ? -3.65718  -35.41843 -9.80767  1.000 27.27865 ?  43  ILE   A CB  1 
ATOM   322  C CG1 . ILE   A 1 43  ? -2.47729  -34.49737 -9.46653  1.000 33.26167 ?  43  ILE   A CG1 1 
ATOM   323  C CG2 . ILE   A 1 43  ? -4.00402  -35.34541 -11.30963 1.000 27.84687 ?  43  ILE   A CG2 1 
ATOM   324  C CD1 . ILE   A 1 43  ? -1.27882  -34.72726 -10.39550 1.000 33.08470 ?  43  ILE   A CD1 1 
ATOM   325  N N   . CYS   A 1 44  ? -4.82136  -34.32611 -6.60827  1.000 32.65862 ?  44  CYS   A N   1 
ATOM   326  C CA  . CYS   A 1 44  ? -4.41554  -34.30626 -5.20417  1.000 33.87904 ?  44  CYS   A CA  1 
ATOM   327  C C   . CYS   A 1 44  ? -5.55122  -34.69949 -4.26775  1.000 38.77447 ?  44  CYS   A C   1 
ATOM   328  O O   . CYS   A 1 44  ? -6.69730  -34.28242 -4.45807  1.000 34.16706 ?  44  CYS   A O   1 
ATOM   329  C CB  . CYS   A 1 44  ? -3.94485  -32.90720 -4.80340  1.000 32.57926 ?  44  CYS   A CB  1 
ATOM   330  S SG  . CYS   A 1 44  ? -2.51178  -32.31645 -5.66478  1.000 34.71070 ?  44  CYS   A SG  1 
ATOM   331  N N   . THR   A 1 45  ? -5.22465  -35.47864 -3.22718  1.000 36.58447 ?  45  THR   A N   1 
ATOM   332  C CA  . THR   A 1 45  ? -6.10692  -35.49375 -2.06954  1.000 37.96477 ?  45  THR   A CA  1 
ATOM   333  C C   . THR   A 1 45  ? -5.92264  -34.19945 -1.28313  1.000 36.60249 ?  45  THR   A C   1 
ATOM   334  O O   . THR   A 1 45  ? -4.98591  -33.43102 -1.52012  1.000 37.36019 ?  45  THR   A O   1 
ATOM   335  C CB  . THR   A 1 45  ? -5.81724  -36.68972 -1.16056  1.000 40.63470 ?  45  THR   A CB  1 
ATOM   336  O OG1 . THR   A 1 45  ? -4.51793  -36.53358 -0.56687  1.000 36.58600 ?  45  THR   A OG1 1 
ATOM   337  C CG2 . THR   A 1 45  ? -5.86534  -37.98853 -1.93973  1.000 39.65478 ?  45  THR   A CG2 1 
ATOM   338  N N   . SER   A 1 46  ? -6.81559  -33.96068 -0.31691  1.000 37.52121 ?  46  SER   A N   1 
ATOM   339  C CA  . SER   A 1 46  ? -6.69318  -32.74577 0.48469   1.000 36.47273 ?  46  SER   A CA  1 
ATOM   340  C C   . SER   A 1 46  ? -5.34934  -32.69784 1.20463   1.000 40.66981 ?  46  SER   A C   1 
ATOM   341  O O   . SER   A 1 46  ? -4.72846  -31.63180 1.31224   1.000 39.65142 ?  46  SER   A O   1 
ATOM   342  C CB  . SER   A 1 46  ? -7.85156  -32.64745 1.48004   1.000 45.40924 ?  46  SER   A CB  1 
ATOM   343  O OG  . SER   A 1 46  ? -7.91938  -33.78767 2.32460   1.000 46.62939 ?  46  SER   A OG  1 
ATOM   344  N N   . GLU   A 1 47  ? -4.87292  -33.84753 1.68639   1.000 35.92790 ?  47  GLU   A N   1 
ATOM   345  C CA  . GLU   A 1 47  ? -3.57096  -33.88251 2.35625   1.000 39.15310 ?  47  GLU   A CA  1 
ATOM   346  C C   . GLU   A 1 47  ? -2.42204  -33.69602 1.36031   1.000 37.96269 ?  47  GLU   A C   1 
ATOM   347  O O   . GLU   A 1 47  ? -1.38806  -33.09380 1.69788   1.000 35.56940 ?  47  GLU   A O   1 
ATOM   348  C CB  . GLU   A 1 47  ? -3.42775  -35.20126 3.12492   1.000 37.73155 ?  47  GLU   A CB  1 
ATOM   349  C CG  . GLU   A 1 47  ? -2.25164  -35.24091 4.08537   1.000 34.09364 ?  47  GLU   A CG  1 
ATOM   350  C CD  . GLU   A 1 47  ? -2.39241  -34.25435 5.24086   1.000 41.79693 ?  47  GLU   A CD  1 
ATOM   351  O OE1 . GLU   A 1 47  ? -3.52928  -33.80448 5.53793   1.000 42.44444 ?  47  GLU   A OE1 1 
ATOM   352  O OE2 . GLU   A 1 47  ? -1.35731  -33.91780 5.85391   1.000 38.99222 -1 47  GLU   A OE2 1 
ATOM   353  N N   . ASP   A 1 48  ? -2.59132  -34.20255 0.12887   1.000 34.31923 ?  48  ASP   A N   1 
ATOM   354  C CA  . ASP   A 1 48  ? -1.60754  -33.99509 -0.93617  1.000 35.48997 ?  48  ASP   A CA  1 
ATOM   355  C C   . ASP   A 1 48  ? -1.34898  -32.51295 -1.19049  1.000 37.99212 ?  48  ASP   A C   1 
ATOM   356  O O   . ASP   A 1 48  ? -0.22316  -32.12663 -1.52569  1.000 38.96955 ?  48  ASP   A O   1 
ATOM   357  C CB  . ASP   A 1 48  ? -2.08401  -34.62458 -2.25275  1.000 38.85609 ?  48  ASP   A CB  1 
ATOM   358  C CG  . ASP   A 1 48  ? -2.00123  -36.13768 -2.27181  1.000 41.98343 ?  48  ASP   A CG  1 
ATOM   359  O OD1 . ASP   A 1 48  ? -1.30657  -36.71874 -1.41345  1.000 41.37410 ?  48  ASP   A OD1 1 
ATOM   360  O OD2 . ASP   A 1 48  ? -2.61106  -36.73527 -3.19241  1.000 41.98510 -1 48  ASP   A OD2 1 
ATOM   361  N N   . MET   A 1 49  ? -2.39412  -31.67560 -1.08863  1.000 39.91313 ?  49  MET   A N   1 
ATOM   362  C CA  . MET   A 1 49  ? -2.28690  -30.27284 -1.49495  1.000 36.19505 ?  49  MET   A CA  1 
ATOM   363  C C   . MET   A 1 49  ? -1.38910  -29.46066 -0.57004  1.000 37.08907 ?  49  MET   A C   1 
ATOM   364  O O   . MET   A 1 49  ? -0.94757  -28.36553 -0.95089  1.000 36.02846 ?  49  MET   A O   1 
ATOM   365  C CB  . MET   A 1 49  ? -3.67719  -29.62607 -1.55682  1.000 36.63628 ?  49  MET   A CB  1 
ATOM   366  C CG  . MET   A 1 49  ? -4.60170  -30.21374 -2.62224  1.000 37.46784 ?  49  MET   A CG  1 
ATOM   367  S SD  . MET   A 1 49  ? -6.31159  -29.60053 -2.52753  1.000 39.60033 ?  49  MET   A SD  1 
ATOM   368  C CE  . MET   A 1 49  ? -7.15336  -30.75695 -3.61462  1.000 34.64766 ?  49  MET   A CE  1 
ATOM   369  N N   . LEU   A 1 50  ? -1.10745  -29.96355 0.63361   1.000 34.71150 ?  50  LEU   A N   1 
ATOM   370  C CA  . LEU   A 1 50  ? -0.21616  -29.23684 1.53306   1.000 36.85159 ?  50  LEU   A CA  1 
ATOM   371  C C   . LEU   A 1 50  ? 1.15748   -29.03383 0.90912   1.000 38.77154 ?  50  LEU   A C   1 
ATOM   372  O O   . LEU   A 1 50  ? 1.74725   -27.95540 1.02898   1.000 41.77508 ?  50  LEU   A O   1 
ATOM   373  C CB  . LEU   A 1 50  ? -0.08557  -29.98015 2.86385   1.000 38.35675 ?  50  LEU   A CB  1 
ATOM   374  C CG  . LEU   A 1 50  ? -1.37125  -30.09290 3.68460   1.000 44.11834 ?  50  LEU   A CG  1 
ATOM   375  C CD1 . LEU   A 1 50  ? -1.08345  -30.76419 5.02808   1.000 41.23420 ?  50  LEU   A CD1 1 
ATOM   376  C CD2 . LEU   A 1 50  ? -2.01220  -28.72270 3.88033   1.000 42.01443 ?  50  LEU   A CD2 1 
ATOM   377  N N   . ASN   A 1 51  ? 1.68789   -30.05943 0.24338   1.000 40.07581 ?  51  ASN   A N   1 
ATOM   378  C CA  . ASN   A 1 51  ? 3.06198   -30.03581 -0.26236  1.000 39.08472 ?  51  ASN   A CA  1 
ATOM   379  C C   . ASN   A 1 51  ? 3.18292   -31.00485 -1.43006  1.000 41.03190 ?  51  ASN   A C   1 
ATOM   380  O O   . ASN   A 1 51  ? 3.85077   -32.04480 -1.33601  1.000 39.58241 ?  51  ASN   A O   1 
ATOM   381  C CB  . ASN   A 1 51  ? 4.04195   -30.39682 0.85463   1.000 44.60154 ?  51  ASN   A CB  1 
ATOM   382  C CG  . ASN   A 1 51  ? 5.48941   -30.24884 0.43630   1.000 48.17391 ?  51  ASN   A CG  1 
ATOM   383  O OD1 . ASN   A 1 51  ? 5.80100   -29.53699 -0.52250  1.000 47.39170 ?  51  ASN   A OD1 1 
ATOM   384  N ND2 . ASN   A 1 51  ? 6.38818   -30.92802 1.15584   1.000 48.27619 ?  51  ASN   A ND2 1 
ATOM   385  N N   . PRO   A 1 52  ? 2.54698   -30.69382 -2.56226  1.000 36.49297 ?  52  PRO   A N   1 
ATOM   386  C CA  . PRO   A 1 52  ? 2.46687   -31.67768 -3.64835  1.000 35.45139 ?  52  PRO   A CA  1 
ATOM   387  C C   . PRO   A 1 52  ? 3.70318   -31.68647 -4.53015  1.000 37.06141 ?  52  PRO   A C   1 
ATOM   388  O O   . PRO   A 1 52  ? 4.29656   -30.64611 -4.82431  1.000 37.45029 ?  52  PRO   A O   1 
ATOM   389  C CB  . PRO   A 1 52  ? 1.24234   -31.21388 -4.44684  1.000 36.89911 ?  52  PRO   A CB  1 
ATOM   390  C CG  . PRO   A 1 52  ? 1.27005   -29.72212 -4.25895  1.000 37.35673 ?  52  PRO   A CG  1 
ATOM   391  C CD  . PRO   A 1 52  ? 1.79638   -29.46510 -2.88009  1.000 37.81686 ?  52  PRO   A CD  1 
ATOM   392  N N   . ASN   A 1 53  ? 4.07873   -32.88576 -4.96485  1.000 37.14847 ?  53  ASN   A N   1 
ATOM   393  C CA  . ASN   A 1 53  ? 5.03111   -33.08025 -6.05235  1.000 31.73649 ?  53  ASN   A CA  1 
ATOM   394  C C   . ASN   A 1 53  ? 4.21445   -33.55125 -7.25380  1.000 36.07578 ?  53  ASN   A C   1 
ATOM   395  O O   . ASN   A 1 53  ? 3.92672   -34.74102 -7.39941  1.000 36.63546 ?  53  ASN   A O   1 
ATOM   396  C CB  . ASN   A 1 53  ? 6.11204   -34.08631 -5.65716  1.000 42.21336 ?  53  ASN   A CB  1 
ATOM   397  C CG  . ASN   A 1 53  ? 7.21893   -34.18865 -6.67993  1.000 40.92501 ?  53  ASN   A CG  1 
ATOM   398  O OD1 . ASN   A 1 53  ? 6.97444   -34.34325 -7.87961  1.000 40.33354 ?  53  ASN   A OD1 1 
ATOM   399  N ND2 . ASN   A 1 53  ? 8.45417   -34.10064 -6.20909  1.000 49.70598 ?  53  ASN   A ND2 1 
ATOM   400  N N   . TYR   A 1 54  ? 3.81935   -32.60660 -8.10575  1.000 33.37432 ?  54  TYR   A N   1 
ATOM   401  C CA  . TYR   A 1 54  ? 2.86176   -32.92165 -9.16021  1.000 33.64503 ?  54  TYR   A CA  1 
ATOM   402  C C   . TYR   A 1 54  ? 3.40411   -33.95307 -10.14145 1.000 36.95930 ?  54  TYR   A C   1 
ATOM   403  O O   . TYR   A 1 54  ? 2.66084   -34.82543 -10.60035 1.000 36.48931 ?  54  TYR   A O   1 
ATOM   404  C CB  . TYR   A 1 54  ? 2.46571   -31.63797 -9.87893  1.000 31.88705 ?  54  TYR   A CB  1 
ATOM   405  C CG  . TYR   A 1 54  ? 1.48819   -30.83205 -9.07573  1.000 30.37237 ?  54  TYR   A CG  1 
ATOM   406  C CD1 . TYR   A 1 54  ? 0.16325   -31.22815 -8.98508  1.000 27.89735 ?  54  TYR   A CD1 1 
ATOM   407  C CD2 . TYR   A 1 54  ? 1.88049   -29.67431 -8.40354  1.000 28.64784 ?  54  TYR   A CD2 1 
ATOM   408  C CE1 . TYR   A 1 54  ? -0.74795  -30.52222 -8.25013  1.000 28.65671 ?  54  TYR   A CE1 1 
ATOM   409  C CE2 . TYR   A 1 54  ? 0.97091   -28.94492 -7.66894  1.000 31.39551 ?  54  TYR   A CE2 1 
ATOM   410  C CZ  . TYR   A 1 54  ? -0.35660  -29.36723 -7.60200  1.000 30.65754 ?  54  TYR   A CZ  1 
ATOM   411  O OH  . TYR   A 1 54  ? -1.29497  -28.64009 -6.88191  1.000 28.55746 ?  54  TYR   A OH  1 
ATOM   412  N N   . GLU   A 1 55  ? 4.68286   -33.85300 -10.50664 1.000 41.58424 ?  55  GLU   A N   1 
ATOM   413  C CA  . GLU   A 1 55  ? 5.25589   -34.84186 -11.41581 1.000 44.39368 ?  55  GLU   A CA  1 
ATOM   414  C C   . GLU   A 1 55  ? 5.14804   -36.24027 -10.82591 1.000 39.13848 ?  55  GLU   A C   1 
ATOM   415  O O   . GLU   A 1 55  ? 4.69404   -37.17795 -11.49789 1.000 38.09946 ?  55  GLU   A O   1 
ATOM   416  C CB  . GLU   A 1 55  ? 6.71446   -34.49331 -11.72487 1.000 44.77356 ?  55  GLU   A CB  1 
ATOM   417  C CG  . GLU   A 1 55  ? 6.87746   -33.25747 -12.59131 1.000 47.58749 ?  55  GLU   A CG  1 
ATOM   418  C CD  . GLU   A 1 55  ? 6.79620   -31.94985 -11.79825 1.000 48.37972 ?  55  GLU   A CD  1 
ATOM   419  O OE1 . GLU   A 1 55  ? 6.71400   -31.98630 -10.54461 1.000 48.06407 ?  55  GLU   A OE1 1 
ATOM   420  O OE2 . GLU   A 1 55  ? 6.82324   -30.87806 -12.43672 1.000 49.66664 -1 55  GLU   A OE2 1 
ATOM   421  N N   . ASP   A 1 56  ? 5.52967   -36.37947 -9.55221  1.000 40.74511 ?  56  ASP   A N   1 
ATOM   422  C CA  . ASP   A 1 56  ? 5.41540   -37.65071 -8.84383  1.000 43.97933 ?  56  ASP   A CA  1 
ATOM   423  C C   . ASP   A 1 56  ? 3.97089   -38.13054 -8.77923  1.000 43.50760 ?  56  ASP   A C   1 
ATOM   424  O O   . ASP   A 1 56  ? 3.68720   -39.31372 -9.00459  1.000 40.68724 ?  56  ASP   A O   1 
ATOM   425  C CB  . ASP   A 1 56  ? 5.98628   -37.49104 -7.43443  1.000 45.58178 ?  56  ASP   A CB  1 
ATOM   426  C CG  . ASP   A 1 56  ? 6.82235   -38.66488 -7.01069  1.000 55.32668 ?  56  ASP   A CG  1 
ATOM   427  O OD1 . ASP   A 1 56  ? 6.31576   -39.80881 -7.07346  1.000 58.95253 ?  56  ASP   A OD1 1 
ATOM   428  O OD2 . ASP   A 1 56  ? 7.99144   -38.44039 -6.62252  1.000 60.27365 -1 56  ASP   A OD2 1 
ATOM   429  N N   . LEU   A 1 57  ? 3.04068   -37.22846 -8.46224  1.000 39.80711 ?  57  LEU   A N   1 
ATOM   430  C CA  . LEU   A 1 57  ? 1.64475   -37.63143 -8.34582  1.000 35.61262 ?  57  LEU   A CA  1 
ATOM   431  C C   . LEU   A 1 57  ? 1.08209   -38.06813 -9.68985  1.000 37.15191 ?  57  LEU   A C   1 
ATOM   432  O O   . LEU   A 1 57  ? 0.28800   -39.01197 -9.75624  1.000 39.65031 ?  57  LEU   A O   1 
ATOM   433  C CB  . LEU   A 1 57  ? 0.81292   -36.48902 -7.76212  1.000 36.05543 ?  57  LEU   A CB  1 
ATOM   434  C CG  . LEU   A 1 57  ? 1.03416   -36.15619 -6.28759  1.000 35.71135 ?  57  LEU   A CG  1 
ATOM   435  C CD1 . LEU   A 1 57  ? 0.25846   -34.88993 -5.89953  1.000 42.01896 ?  57  LEU   A CD1 1 
ATOM   436  C CD2 . LEU   A 1 57  ? 0.60017   -37.32756 -5.42240  1.000 44.58950 ?  57  LEU   A CD2 1 
ATOM   437  N N   . LEU   A 1 58  ? 1.48875   -37.40290 -10.77258 1.000 34.54530 ?  58  LEU   A N   1 
ATOM   438  C CA  . LEU   A 1 58  ? 0.91457   -37.66435 -12.08550 1.000 35.95402 ?  58  LEU   A CA  1 
ATOM   439  C C   . LEU   A 1 58  ? 1.48174   -38.92494 -12.70731 1.000 36.94410 ?  58  LEU   A C   1 
ATOM   440  O O   . LEU   A 1 58  ? 0.77918   -39.60560 -13.46165 1.000 34.71636 ?  58  LEU   A O   1 
ATOM   441  C CB  . LEU   A 1 58  ? 1.14636   -36.47328 -13.02435 1.000 38.03785 ?  58  LEU   A CB  1 
ATOM   442  C CG  . LEU   A 1 58  ? 0.49695   -36.53898 -14.41472 1.000 40.77436 ?  58  LEU   A CG  1 
ATOM   443  C CD1 . LEU   A 1 58  ? -1.01594  -36.71045 -14.32003 1.000 38.26095 ?  58  LEU   A CD1 1 
ATOM   444  C CD2 . LEU   A 1 58  ? 0.82760   -35.29203 -15.24354 1.000 38.21556 ?  58  LEU   A CD2 1 
ATOM   445  N N   . ILE   A 1 59  ? 2.74087   -39.25657 -12.41152 1.000 38.28899 ?  59  ILE   A N   1 
ATOM   446  C CA  . ILE   A 1 59  ? 3.27829   -40.48462 -12.97420 1.000 38.81988 ?  59  ILE   A CA  1 
ATOM   447  C C   . ILE   A 1 59  ? 2.53721   -41.68934 -12.42356 1.000 36.94391 ?  59  ILE   A C   1 
ATOM   448  O O   . ILE   A 1 59  ? 2.53902   -42.75374 -13.04482 1.000 44.01528 ?  59  ILE   A O   1 
ATOM   449  C CB  . ILE   A 1 59  ? 4.80010   -40.58156 -12.72536 1.000 44.69225 ?  59  ILE   A CB  1 
ATOM   450  C CG1 . ILE   A 1 59  ? 5.46048   -41.31833 -13.89316 1.000 51.99519 ?  59  ILE   A CG1 1 
ATOM   451  C CG2 . ILE   A 1 59  ? 5.08783   -41.26743 -11.40850 1.000 45.93155 ?  59  ILE   A CG2 1 
ATOM   452  C CD1 . ILE   A 1 59  ? 6.93711   -41.56434 -13.71966 1.000 52.43537 ?  59  ILE   A CD1 1 
ATOM   453  N N   . ARG   A 1 60  ? 1.87466   -41.53921 -11.28182 1.000 37.52416 ?  60  ARG   A N   1 
ATOM   454  C CA  . ARG   A 1 60  ? 1.08840   -42.62431 -10.71970 1.000 41.80351 ?  60  ARG   A CA  1 
ATOM   455  C C   . ARG   A 1 60  ? -0.26723  -42.77325 -11.39895 1.000 42.45425 ?  60  ARG   A C   1 
ATOM   456  O O   . ARG   A 1 60  ? -0.90505  -43.82051 -11.24668 1.000 40.59860 ?  60  ARG   A O   1 
ATOM   457  C CB  . ARG   A 1 60  ? 0.88808   -42.40347 -9.21782  1.000 42.97114 ?  60  ARG   A CB  1 
ATOM   458  C CG  . ARG   A 1 60  ? 2.18075   -42.22809 -8.42360  1.000 49.58983 ?  60  ARG   A CG  1 
ATOM   459  C CD  . ARG   A 1 60  ? 2.01311   -42.70536 -6.98717  1.000 55.09244 ?  60  ARG   A CD  1 
ATOM   460  N NE  . ARG   A 1 60  ? 0.99484   -41.97155 -6.23631  1.000 62.18931 ?  60  ARG   A NE  1 
ATOM   461  C CZ  . ARG   A 1 60  ? 1.21409   -41.36381 -5.07582  1.000 65.59728 ?  60  ARG   A CZ  1 
ATOM   462  N NH1 . ARG   A 1 60  ? 2.41389   -41.35957 -4.51501  1.000 67.15715 ?  60  ARG   A NH1 1 
ATOM   463  N NH2 . ARG   A 1 60  ? 0.20152   -40.75853 -4.45444  1.000 65.33182 ?  60  ARG   A NH2 1 
ATOM   464  N N   . LYS   A 1 61  ? -0.71828  -41.75901 -12.13678 1.000 35.07613 ?  61  LYS   A N   1 
ATOM   465  C CA  . LYS   A 1 61  ? -2.04603  -41.76179 -12.74157 1.000 36.61177 ?  61  LYS   A CA  1 
ATOM   466  C C   . LYS   A 1 61  ? -1.98942  -42.28774 -14.16528 1.000 32.43972 ?  61  LYS   A C   1 
ATOM   467  O O   . LYS   A 1 61  ? -1.00585  -42.08421 -14.88182 1.000 35.10533 ?  61  LYS   A O   1 
ATOM   468  C CB  . LYS   A 1 61  ? -2.63980  -40.34484 -12.76247 1.000 35.10517 ?  61  LYS   A CB  1 
ATOM   469  C CG  . LYS   A 1 61  ? -2.83547  -39.67935 -11.40638 1.000 36.83655 ?  61  LYS   A CG  1 
ATOM   470  C CD  . LYS   A 1 61  ? -3.74452  -40.48831 -10.50864 1.000 37.43342 ?  61  LYS   A CD  1 
ATOM   471  C CE  . LYS   A 1 61  ? -3.96422  -39.76580 -9.19381  1.000 43.07874 ?  61  LYS   A CE  1 
ATOM   472  N NZ  . LYS   A 1 61  ? -4.68438  -40.61365 -8.20187  1.000 51.13265 ?  61  LYS   A NZ  1 
ATOM   473  N N   . SER   A 1 62  ? -3.07561  -42.93449 -14.59102 1.000 32.73346 ?  62  SER   A N   1 
ATOM   474  C CA  . SER   A 1 62  ? -3.25774  -43.28148 -15.99011 1.000 29.94206 ?  62  SER   A CA  1 
ATOM   475  C C   . SER   A 1 62  ? -4.58466  -42.71392 -16.46958 1.000 29.22125 ?  62  SER   A C   1 
ATOM   476  O O   . SER   A 1 62  ? -5.37515  -42.18861 -15.68313 1.000 30.70292 ?  62  SER   A O   1 
ATOM   477  C CB  . SER   A 1 62  ? -3.20162  -44.79832 -16.21945 1.000 40.21985 ?  62  SER   A CB  1 
ATOM   478  O OG  . SER   A 1 62  ? -3.58396  -45.50245 -15.05392 1.000 46.56756 ?  62  SER   A OG  1 
ATOM   479  N N   . ASN   A 1 63  ? -4.81220  -42.82731 -17.77516 1.000 28.32237 ?  63  ASN   A N   1 
ATOM   480  C CA  . ASN   A 1 63  ? -6.05099  -42.32084 -18.36396 1.000 27.93705 ?  63  ASN   A CA  1 
ATOM   481  C C   . ASN   A 1 63  ? -7.26516  -42.80849 -17.59266 1.000 30.21507 ?  63  ASN   A C   1 
ATOM   482  O O   . ASN   A 1 63  ? -8.24456  -42.06937 -17.42442 1.000 30.69480 ?  63  ASN   A O   1 
ATOM   483  C CB  . ASN   A 1 63  ? -6.16549  -42.75775 -19.81823 1.000 29.01555 ?  63  ASN   A CB  1 
ATOM   484  C CG  . ASN   A 1 63  ? -5.13467  -42.10693 -20.70543 1.000 32.75727 ?  63  ASN   A CG  1 
ATOM   485  O OD1 . ASN   A 1 63  ? -4.71817  -40.96101 -20.48145 1.000 30.93254 ?  63  ASN   A OD1 1 
ATOM   486  N ND2 . ASN   A 1 63  ? -4.70532  -42.83797 -21.72015 1.000 34.54095 ?  63  ASN   A ND2 1 
ATOM   487  N N   . HIS   A 1 64  ? -7.22523  -44.05264 -17.11115 1.000 31.22551 ?  64  HIS   A N   1 
ATOM   488  C CA  . HIS   A 1 64  ? -8.43482  -44.61768 -16.53583 1.000 31.68164 ?  64  HIS   A CA  1 
ATOM   489  C C   . HIS   A 1 64  ? -8.70972  -44.13192 -15.11993 1.000 32.62360 ?  64  HIS   A C   1 
ATOM   490  O O   . HIS   A 1 64  ? -9.76070  -44.47177 -14.56913 1.000 33.35597 ?  64  HIS   A O   1 
ATOM   491  C CB  . HIS   A 1 64  ? -8.38500  -46.15673 -16.57918 1.000 36.92023 ?  64  HIS   A CB  1 
ATOM   492  C CG  . HIS   A 1 64  ? -7.31112  -46.75208 -15.73058 1.000 37.23190 ?  64  HIS   A CG  1 
ATOM   493  N ND1 . HIS   A 1 64  ? -7.41261  -46.84288 -14.36084 1.000 42.05222 ?  64  HIS   A ND1 1 
ATOM   494  C CD2 . HIS   A 1 64  ? -6.12521  -47.31630 -16.05941 1.000 39.13838 ?  64  HIS   A CD2 1 
ATOM   495  C CE1 . HIS   A 1 64  ? -6.32517  -47.41844 -13.87718 1.000 42.88299 ?  64  HIS   A CE1 1 
ATOM   496  N NE2 . HIS   A 1 64  ? -5.52874  -47.71493 -14.88851 1.000 43.35940 ?  64  HIS   A NE2 1 
ATOM   497  N N   . ASN   A 1 65  ? -7.82867  -43.32258 -14.52770 1.000 28.56718 ?  65  ASN   A N   1 
ATOM   498  C CA  . ASN   A 1 65  ? -8.09215  -42.72224 -13.22773 1.000 27.60064 ?  65  ASN   A CA  1 
ATOM   499  C C   . ASN   A 1 65  ? -8.86761  -41.40691 -13.30071 1.000 25.17701 ?  65  ASN   A C   1 
ATOM   500  O O   . ASN   A 1 65  ? -9.19217  -40.85370 -12.24765 1.000 27.59114 ?  65  ASN   A O   1 
ATOM   501  C CB  . ASN   A 1 65  ? -6.78420  -42.47571 -12.48301 1.000 30.51170 ?  65  ASN   A CB  1 
ATOM   502  C CG  . ASN   A 1 65  ? -6.02111  -43.75793 -12.23083 1.000 35.01424 ?  65  ASN   A CG  1 
ATOM   503  O OD1 . ASN   A 1 65  ? -4.83368  -43.85872 -12.52752 1.000 34.67745 ?  65  ASN   A OD1 1 
ATOM   504  N ND2 . ASN   A 1 65  ? -6.72495  -44.76304 -11.71599 1.000 37.36795 ?  65  ASN   A ND2 1 
ATOM   505  N N   . PHE   A 1 66  ? -9.19283  -40.91496 -14.49281 1.000 27.08568 ?  66  PHE   A N   1 
ATOM   506  C CA  . PHE   A 1 66  ? -9.83043  -39.61034 -14.63519 1.000 26.10189 ?  66  PHE   A CA  1 
ATOM   507  C C   . PHE   A 1 66  ? -11.26629 -39.78299 -15.07372 1.000 22.80403 ?  66  PHE   A C   1 
ATOM   508  O O   . PHE   A 1 66  ? -11.52498 -40.41658 -16.09519 1.000 25.88148 ?  66  PHE   A O   1 
ATOM   509  C CB  . PHE   A 1 66  ? -9.10078  -38.73393 -15.65594 1.000 25.10718 ?  66  PHE   A CB  1 
ATOM   510  C CG  . PHE   A 1 66  ? -7.73774  -38.35095 -15.22702 1.000 25.26725 ?  66  PHE   A CG  1 
ATOM   511  C CD1 . PHE   A 1 66  ? -7.53827  -37.21895 -14.46400 1.000 27.97875 ?  66  PHE   A CD1 1 
ATOM   512  C CD2 . PHE   A 1 66  ? -6.64788  -39.12689 -15.57802 1.000 27.61566 ?  66  PHE   A CD2 1 
ATOM   513  C CE1 . PHE   A 1 66  ? -6.26780  -36.86366 -14.05259 1.000 32.24171 ?  66  PHE   A CE1 1 
ATOM   514  C CE2 . PHE   A 1 66  ? -5.37530  -38.77159 -15.18062 1.000 28.20451 ?  66  PHE   A CE2 1 
ATOM   515  C CZ  . PHE   A 1 66  ? -5.18172  -37.64794 -14.41965 1.000 30.94738 ?  66  PHE   A CZ  1 
ATOM   516  N N   . LEU   A 1 67  ? -12.18480 -39.17709 -14.32401 1.000 22.10549 ?  67  LEU   A N   1 
ATOM   517  C CA  . LEU   A 1 67  ? -13.60685 -39.19669 -14.63831 1.000 23.40884 ?  67  LEU   A CA  1 
ATOM   518  C C   . LEU   A 1 67  ? -13.99368 -37.82403 -15.17793 1.000 21.32452 ?  67  LEU   A C   1 
ATOM   519  O O   . LEU   A 1 67  ? -14.06263 -36.86812 -14.40865 1.000 23.67079 ?  67  LEU   A O   1 
ATOM   520  C CB  . LEU   A 1 67  ? -14.41852 -39.52369 -13.38858 1.000 23.95424 ?  67  LEU   A CB  1 
ATOM   521  C CG  . LEU   A 1 67  ? -15.93527 -39.50121 -13.57863 1.000 23.97565 ?  67  LEU   A CG  1 
ATOM   522  C CD1 . LEU   A 1 67  ? -16.40446 -40.48770 -14.64656 1.000 23.04266 ?  67  LEU   A CD1 1 
ATOM   523  C CD2 . LEU   A 1 67  ? -16.63399 -39.73885 -12.22977 1.000 24.84823 ?  67  LEU   A CD2 1 
ATOM   524  N N   . VAL   A 1 68  ? -14.29214 -37.74884 -16.46698 1.000 22.78193 ?  68  VAL   A N   1 
ATOM   525  C CA  . VAL   A 1 68  ? -14.75564 -36.51980 -17.11559 1.000 22.71893 ?  68  VAL   A CA  1 
ATOM   526  C C   . VAL   A 1 68  ? -16.21918 -36.69686 -17.46819 1.000 23.60371 ?  68  VAL   A C   1 
ATOM   527  O O   . VAL   A 1 68  ? -16.58939 -37.66560 -18.13344 1.000 25.12163 ?  68  VAL   A O   1 
ATOM   528  C CB  . VAL   A 1 68  ? -13.91567 -36.21295 -18.36567 1.000 22.71032 ?  68  VAL   A CB  1 
ATOM   529  C CG1 . VAL   A 1 68  ? -14.48170 -34.96198 -19.13558 1.000 25.39957 ?  68  VAL   A CG1 1 
ATOM   530  C CG2 . VAL   A 1 68  ? -12.46919 -36.03141 -17.97761 1.000 24.96178 ?  68  VAL   A CG2 1 
ATOM   531  N N   . GLN   A 1 69  ? -17.06567 -35.76830 -17.02845 1.000 21.68140 ?  69  GLN   A N   1 
ATOM   532  C CA  . GLN   A 1 69  ? -18.48997 -35.90431 -17.27541 1.000 21.99765 ?  69  GLN   A CA  1 
ATOM   533  C C   . GLN   A 1 69  ? -19.02305 -34.59447 -17.81523 1.000 22.02504 ?  69  GLN   A C   1 
ATOM   534  O O   . GLN   A 1 69  ? -18.70270 -33.53857 -17.28381 1.000 22.94969 ?  69  GLN   A O   1 
ATOM   535  C CB  . GLN   A 1 69  ? -19.25560 -36.28464 -15.99774 1.000 25.50250 ?  69  GLN   A CB  1 
ATOM   536  C CG  . GLN   A 1 69  ? -18.76035 -37.59497 -15.39164 1.000 26.41984 ?  69  GLN   A CG  1 
ATOM   537  C CD  . GLN   A 1 69  ? -19.25633 -37.81090 -13.98250 1.000 28.43344 ?  69  GLN   A CD  1 
ATOM   538  O OE1 . GLN   A 1 69  ? -18.89429 -37.07686 -13.05678 1.000 29.11793 ?  69  GLN   A OE1 1 
ATOM   539  N NE2 . GLN   A 1 69  ? -20.09502 -38.82860 -13.80994 1.000 30.22984 ?  69  GLN   A NE2 1 
ATOM   540  N N   . ALA   A 1 70  ? -19.83818 -34.67938 -18.86690 1.000 26.10773 ?  70  ALA   A N   1 
ATOM   541  C CA  . ALA   A 1 70  ? -20.65496 -33.56492 -19.35263 1.000 29.91954 ?  70  ALA   A CA  1 
ATOM   542  C C   . ALA   A 1 70  ? -22.05872 -33.88188 -18.86336 1.000 34.35655 ?  70  ALA   A C   1 
ATOM   543  O O   . ALA   A 1 70  ? -22.71753 -34.79059 -19.37999 1.000 30.29904 ?  70  ALA   A O   1 
ATOM   544  C CB  . ALA   A 1 70  ? -20.59086 -33.43700 -20.87147 1.000 32.49195 ?  70  ALA   A CB  1 
ATOM   545  N N   . GLY   A 1 71  ? -22.48771 -33.18748 -17.81860 1.000 34.06551 ?  71  GLY   A N   1 
ATOM   546  C CA  . GLY   A 1 71  ? -23.66048 -33.65768 -17.10458 1.000 35.78668 ?  71  GLY   A CA  1 
ATOM   547  C C   . GLY   A 1 71  ? -23.39188 -35.03505 -16.53720 1.000 35.28852 ?  71  GLY   A C   1 
ATOM   548  O O   . GLY   A 1 71  ? -22.36719 -35.27409 -15.88915 1.000 40.74859 ?  71  GLY   A O   1 
ATOM   549  N N   . ASN   A 1 72  ? -24.31281 -35.96326 -16.77906 1.000 41.95931 ?  72  ASN   A N   1 
ATOM   550  C CA  . ASN   A 1 72  ? -24.12481 -37.35379 -16.38461 1.000 42.28715 ?  72  ASN   A CA  1 
ATOM   551  C C   . ASN   A 1 72  ? -23.43378 -38.19059 -17.45463 1.000 38.77458 ?  72  ASN   A C   1 
ATOM   552  O O   . ASN   A 1 72  ? -23.25939 -39.39804 -17.25258 1.000 41.18217 ?  72  ASN   A O   1 
ATOM   553  C CB  . ASN   A 1 72  ? -25.46787 -38.00773 -16.04027 1.000 45.91135 ?  72  ASN   A CB  1 
ATOM   554  C CG  . ASN   A 1 72  ? -25.85688 -37.82684 -14.58157 1.000 48.84919 ?  72  ASN   A CG  1 
ATOM   555  O OD1 . ASN   A 1 72  ? -25.22516 -37.06887 -13.83501 1.000 47.79707 ?  72  ASN   A OD1 1 
ATOM   556  N ND2 . ASN   A 1 72  ? -26.91794 -38.51933 -14.17149 1.000 53.26059 ?  72  ASN   A ND2 1 
ATOM   557  N N   . VAL   A 1 73  ? -23.03698 -37.59678 -18.58013 1.000 32.79827 ?  73  VAL   A N   1 
ATOM   558  C CA  . VAL   A 1 73  ? -22.44860 -38.35817 -19.67579 1.000 33.67030 ?  73  VAL   A CA  1 
ATOM   559  C C   . VAL   A 1 73  ? -20.93512 -38.40952 -19.49196 1.000 31.50998 ?  73  VAL   A C   1 
ATOM   560  O O   . VAL   A 1 73  ? -20.26434 -37.37711 -19.51499 1.000 27.30072 ?  73  VAL   A O   1 
ATOM   561  C CB  . VAL   A 1 73  ? -22.82118 -37.74430 -21.03081 1.000 37.07855 ?  73  VAL   A CB  1 
ATOM   562  C CG1 . VAL   A 1 73  ? -22.20583 -38.55119 -22.15752 1.000 36.30602 ?  73  VAL   A CG1 1 
ATOM   563  C CG2 . VAL   A 1 73  ? -24.34836 -37.67093 -21.16896 1.000 36.46754 ?  73  VAL   A CG2 1 
ATOM   564  N N   . GLN   A 1 74  ? -20.38281 -39.60526 -19.31743 1.000 28.69062 ?  74  GLN   A N   1 
ATOM   565  C CA  . GLN   A 1 74  ? -18.93260 -39.71518 -19.18850 1.000 24.88907 ?  74  GLN   A CA  1 
ATOM   566  C C   . GLN   A 1 74  ? -18.25991 -39.57194 -20.54813 1.000 28.83756 ?  74  GLN   A C   1 
ATOM   567  O O   . GLN   A 1 74  ? -18.73200 -40.12065 -21.54546 1.000 31.11143 ?  74  GLN   A O   1 
ATOM   568  C CB  . GLN   A 1 74  ? -18.54268 -41.05976 -18.56336 1.000 27.55832 ?  74  GLN   A CB  1 
ATOM   569  C CG  . GLN   A 1 74  ? -17.05393 -41.32234 -18.57511 1.000 28.92595 ?  74  GLN   A CG  1 
ATOM   570  C CD  . GLN   A 1 74  ? -16.70247 -42.61540 -17.86506 1.000 31.63045 ?  74  GLN   A CD  1 
ATOM   571  O OE1 . GLN   A 1 74  ? -17.58234 -43.44084 -17.62623 1.000 33.24606 ?  74  GLN   A OE1 1 
ATOM   572  N NE2 . GLN   A 1 74  ? -15.43279 -42.79151 -17.51182 1.000 30.91015 ?  74  GLN   A NE2 1 
ATOM   573  N N   . LEU   A 1 75  ? -17.13229 -38.85990 -20.57463 1.000 24.62824 ?  75  LEU   A N   1 
ATOM   574  C CA  . LEU   A 1 75  ? -16.24981 -38.72936 -21.73136 1.000 25.98050 ?  75  LEU   A CA  1 
ATOM   575  C C   . LEU   A 1 75  ? -14.98633 -39.52320 -21.43776 1.000 26.97204 ?  75  LEU   A C   1 
ATOM   576  O O   . LEU   A 1 75  ? -14.23002 -39.17205 -20.52148 1.000 27.92781 ?  75  LEU   A O   1 
ATOM   577  C CB  . LEU   A 1 75  ? -15.88735 -37.26452 -21.99963 1.000 25.32391 ?  75  LEU   A CB  1 
ATOM   578  C CG  . LEU   A 1 75  ? -17.04568 -36.29486 -22.26404 1.000 26.72266 ?  75  LEU   A CG  1 
ATOM   579  C CD1 . LEU   A 1 75  ? -16.51759 -34.85290 -22.52786 1.000 27.98559 ?  75  LEU   A CD1 1 
ATOM   580  C CD2 . LEU   A 1 75  ? -17.88160 -36.78112 -23.41337 1.000 32.60625 ?  75  LEU   A CD2 1 
ATOM   581  N N   . ARG   A 1 76  ? -14.76789 -40.59070 -22.19770 1.000 29.18075 ?  76  ARG   A N   1 
ATOM   582  C CA  . ARG   A 1 76  ? -13.62666 -41.45742 -21.95083 1.000 27.91657 ?  76  ARG   A CA  1 
ATOM   583  C C   . ARG   A 1 76  ? -12.33242 -40.71225 -22.24953 1.000 27.18870 ?  76  ARG   A C   1 
ATOM   584  O O   . ARG   A 1 76  ? -12.19382 -40.10863 -23.31507 1.000 27.59565 ?  76  ARG   A O   1 
ATOM   585  C CB  . ARG   A 1 76  ? -13.72399 -42.71037 -22.81277 1.000 32.99370 ?  76  ARG   A CB  1 
ATOM   586  C CG  . ARG   A 1 76  ? -12.59470 -43.70290 -22.64942 1.000 41.61283 ?  76  ARG   A CG  1 
ATOM   587  C CD  . ARG   A 1 76  ? -12.90243 -44.96594 -23.45441 1.000 47.15317 ?  76  ARG   A CD  1 
ATOM   588  N NE  . ARG   A 1 76  ? -13.10019 -44.66711 -24.87121 1.000 48.96475 ?  76  ARG   A NE  1 
ATOM   589  C CZ  . ARG   A 1 76  ? -12.23209 -44.95616 -25.83355 1.000 51.22160 ?  76  ARG   A CZ  1 
ATOM   590  N NH1 . ARG   A 1 76  ? -11.10654 -45.61046 -25.57937 1.000 50.55025 ?  76  ARG   A NH1 1 
ATOM   591  N NH2 . ARG   A 1 76  ? -12.50230 -44.58707 -27.08457 1.000 44.72216 ?  76  ARG   A NH2 1 
ATOM   592  N N   . VAL   A 1 77  ? -11.37521 -40.78903 -21.32251 1.000 27.42305 ?  77  VAL   A N   1 
ATOM   593  C CA  . VAL   A 1 77  ? -10.07842 -40.12425 -21.46158 1.000 26.39239 ?  77  VAL   A CA  1 
ATOM   594  C C   . VAL   A 1 77  ? -9.13230  -41.06345 -22.19673 1.000 27.07092 ?  77  VAL   A C   1 
ATOM   595  O O   . VAL   A 1 77  ? -8.96454  -42.22045 -21.78828 1.000 28.24676 ?  77  VAL   A O   1 
ATOM   596  C CB  . VAL   A 1 77  ? -9.50501  -39.74700 -20.08180 1.000 28.36990 ?  77  VAL   A CB  1 
ATOM   597  C CG1 . VAL   A 1 77  ? -8.09564  -39.19838 -20.19301 1.000 25.74908 ?  77  VAL   A CG1 1 
ATOM   598  C CG2 . VAL   A 1 77  ? -10.40795 -38.70520 -19.38954 1.000 28.33992 ?  77  VAL   A CG2 1 
ATOM   599  N N   . ILE   A 1 78  ? -8.49080  -40.57112 -23.25678 1.000 27.54834 ?  78  ILE   A N   1 
ATOM   600  C CA  . ILE   A 1 78  ? -7.59191  -41.39595 -24.06208 1.000 27.77700 ?  78  ILE   A CA  1 
ATOM   601  C C   . ILE   A 1 78  ? -6.16602  -40.86402 -24.07335 1.000 31.61146 ?  78  ILE   A C   1 
ATOM   602  O O   . ILE   A 1 78  ? -5.29028  -41.46226 -24.72323 1.000 31.26464 ?  78  ILE   A O   1 
ATOM   603  C CB  . ILE   A 1 78  ? -8.10820  -41.56965 -25.50361 1.000 27.88990 ?  78  ILE   A CB  1 
ATOM   604  C CG1 . ILE   A 1 78  ? -8.09870  -40.23953 -26.25756 1.000 29.53096 ?  78  ILE   A CG1 1 
ATOM   605  C CG2 . ILE   A 1 78  ? -9.51450  -42.18995 -25.49957 1.000 31.69720 ?  78  ILE   A CG2 1 
ATOM   606  C CD1 . ILE   A 1 78  ? -8.63915  -40.34841 -27.67436 1.000 29.20333 ?  78  ILE   A CD1 1 
ATOM   607  N N   . GLY   A 1 79  ? -5.90813  -39.74526 -23.40454 1.000 28.60152 ?  79  GLY   A N   1 
ATOM   608  C CA  . GLY   A 1 79  ? -4.52748  -39.32979 -23.19646 1.000 29.86630 ?  79  GLY   A CA  1 
ATOM   609  C C   . GLY   A 1 79  ? -4.47541  -38.23754 -22.15319 1.000 27.11977 ?  79  GLY   A C   1 
ATOM   610  O O   . GLY   A 1 79  ? -5.48127  -37.60480 -21.85757 1.000 26.11181 ?  79  GLY   A O   1 
ATOM   611  N N   . HIS   A 1 80  ? -3.29654  -38.02100 -21.59440 1.000 27.12121 ?  80  HIS   A N   1 
ATOM   612  C CA  . HIS   A 1 80  ? -3.20787  -36.95627 -20.59718 1.000 30.49127 ?  80  HIS   A CA  1 
ATOM   613  C C   . HIS   A 1 80  ? -1.80339  -36.39381 -20.58140 1.000 33.46030 ?  80  HIS   A C   1 
ATOM   614  O O   . HIS   A 1 80  ? -0.83753  -37.10563 -20.85386 1.000 31.28121 ?  80  HIS   A O   1 
ATOM   615  C CB  . HIS   A 1 80  ? -3.57253  -37.42773 -19.18235 1.000 30.72345 ?  80  HIS   A CB  1 
ATOM   616  C CG  . HIS   A 1 80  ? -2.61712  -38.43036 -18.61098 1.000 33.91965 ?  80  HIS   A CG  1 
ATOM   617  N ND1 . HIS   A 1 80  ? -2.69699  -39.77613 -18.90217 1.000 34.01793 ?  80  HIS   A ND1 1 
ATOM   618  C CD2 . HIS   A 1 80  ? -1.56082  -38.28731 -17.77428 1.000 31.11000 ?  80  HIS   A CD2 1 
ATOM   619  C CE1 . HIS   A 1 80  ? -1.73518  -40.42102 -18.26237 1.000 34.49349 ?  80  HIS   A CE1 1 
ATOM   620  N NE2 . HIS   A 1 80  ? -1.02861  -39.54055 -17.57399 1.000 35.48576 ?  80  HIS   A NE2 1 
ATOM   621  N N   . SER   A 1 81  ? -1.70381  -35.09756 -20.27104 1.000 28.75559 ?  81  SER   A N   1 
ATOM   622  C CA  . SER   A 1 81  ? -0.40341  -34.45930 -20.10087 1.000 29.02509 ?  81  SER   A CA  1 
ATOM   623  C C   . SER   A 1 81  ? -0.56482  -33.24435 -19.20310 1.000 33.57613 ?  81  SER   A C   1 
ATOM   624  O O   . SER   A 1 81  ? -1.67645  -32.75397 -19.00569 1.000 27.18956 ?  81  SER   A O   1 
ATOM   625  C CB  . SER   A 1 81  ? 0.19764   -34.03959 -21.44444 1.000 31.82418 ?  81  SER   A CB  1 
ATOM   626  O OG  . SER   A 1 81  ? -0.60351  -33.08580 -22.09334 1.000 36.09331 ?  81  SER   A OG  1 
ATOM   627  N N   . MET   A 1 82  ? 0.55848   -32.78382 -18.64011 1.000 29.05758 ?  82  MET   A N   1 
ATOM   628  C CA  . MET   A 1 82  ? 0.59396   -31.60562 -17.77839 1.000 31.54067 ?  82  MET   A CA  1 
ATOM   629  C C   . MET   A 1 82  ? 1.34951   -30.48797 -18.48123 1.000 33.60322 ?  82  MET   A C   1 
ATOM   630  O O   . MET   A 1 82  ? 2.45901   -30.70922 -18.97202 1.000 30.24121 ?  82  MET   A O   1 
ATOM   631  C CB  . MET   A 1 82  ? 1.27487   -31.93247 -16.44670 1.000 28.42936 ?  82  MET   A CB  1 
ATOM   632  C CG  . MET   A 1 82  ? 1.27269   -30.79782 -15.46208 1.000 31.48702 ?  82  MET   A CG  1 
ATOM   633  S SD  . MET   A 1 82  ? 1.79744   -31.31391 -13.83929 1.000 35.45644 ?  82  MET   A SD  1 
ATOM   634  C CE  . MET   A 1 82  ? 3.47957   -31.76292 -14.24951 1.000 37.32603 ?  82  MET   A CE  1 
ATOM   635  N N   . GLN   A 1 83  ? 0.74553   -29.29458 -18.54600 1.000 29.23610 ?  83  GLN   A N   1 
ATOM   636  C CA  . GLN   A 1 83  ? 1.39428   -28.10098 -19.08119 1.000 29.89078 ?  83  GLN   A CA  1 
ATOM   637  C C   . GLN   A 1 83  ? 1.32079   -27.06708 -17.97080 1.000 28.57466 ?  83  GLN   A C   1 
ATOM   638  O O   . GLN   A 1 83  ? 0.23729   -26.54993 -17.67693 1.000 27.57225 ?  83  GLN   A O   1 
ATOM   639  C CB  . GLN   A 1 83  ? 0.71761   -27.60782 -20.36085 1.000 32.57479 ?  83  GLN   A CB  1 
ATOM   640  C CG  . GLN   A 1 83  ? 1.36995   -26.36638 -20.95645 1.000 34.10924 ?  83  GLN   A CG  1 
ATOM   641  C CD  . GLN   A 1 83  ? 0.67048   -25.83959 -22.18696 1.000 34.18069 ?  83  GLN   A CD  1 
ATOM   642  O OE1 . GLN   A 1 83  ? -0.44031  -26.26007 -22.53229 1.000 37.06022 ?  83  GLN   A OE1 1 
ATOM   643  N NE2 . GLN   A 1 83  ? 1.31333   -24.89207 -22.85899 1.000 37.28010 ?  83  GLN   A NE2 1 
ATOM   644  N N   . ASN   A 1 84  ? 2.45311   -26.83104 -17.30144 1.000 29.77578 ?  84  ASN   A N   1 
ATOM   645  C CA  . ASN   A 1 84  ? 2.53855   -25.87983 -16.19677 1.000 27.01206 ?  84  ASN   A CA  1 
ATOM   646  C C   . ASN   A 1 84  ? 1.52184   -26.30959 -15.13968 1.000 31.37371 ?  84  ASN   A C   1 
ATOM   647  O O   . ASN   A 1 84  ? 1.57930   -27.46432 -14.68081 1.000 28.05123 ?  84  ASN   A O   1 
ATOM   648  C CB  . ASN   A 1 84  ? 2.38272   -24.47272 -16.75140 1.000 28.60791 ?  84  ASN   A CB  1 
ATOM   649  C CG  . ASN   A 1 84  ? 3.46706   -24.12670 -17.76176 1.000 33.35378 ?  84  ASN   A CG  1 
ATOM   650  O OD1 . ASN   A 1 84  ? 4.65295   -24.27789 -17.47444 1.000 34.56525 ?  84  ASN   A OD1 1 
ATOM   651  N ND2 . ASN   A 1 84  ? 3.06623   -23.70875 -18.95868 1.000 29.44559 ?  84  ASN   A ND2 1 
ATOM   652  N N   . CYS   A 1 85  ? 0.58361   -25.44928 -14.72440 1.000 25.27657 ?  85  CYS   A N   1 
ATOM   653  C CA  . CYS   A 1 85  ? -0.37080  -25.82705 -13.69577 1.000 24.32561 ?  85  CYS   A CA  1 
ATOM   654  C C   . CYS   A 1 85  ? -1.69854  -26.33090 -14.26359 1.000 23.09488 ?  85  CYS   A C   1 
ATOM   655  O O   . CYS   A 1 85  ? -2.67504  -26.43678 -13.51363 1.000 25.87774 ?  85  CYS   A O   1 
ATOM   656  C CB  . CYS   A 1 85  ? -0.63803  -24.65736 -12.75827 1.000 24.46365 ?  85  CYS   A CB  1 
ATOM   657  S SG  . CYS   A 1 85  ? 0.86376   -24.04580 -11.91564 1.000 28.75738 ?  85  CYS   A SG  1 
ATOM   658  N N   . VAL   A 1 86  ? -1.75838  -26.66755 -15.54285 1.000 26.15294 ?  86  VAL   A N   1 
ATOM   659  C CA  . VAL   A 1 86  ? -2.98739  -27.17919 -16.13717 1.000 26.15662 ?  86  VAL   A CA  1 
ATOM   660  C C   . VAL   A 1 86  ? -2.76396  -28.61633 -16.58988 1.000 30.02418 ?  86  VAL   A C   1 
ATOM   661  O O   . VAL   A 1 86  ? -1.68851  -28.97270 -17.08019 1.000 28.11483 ?  86  VAL   A O   1 
ATOM   662  C CB  . VAL   A 1 86  ? -3.46285  -26.27710 -17.29925 1.000 26.78243 ?  86  VAL   A CB  1 
ATOM   663  C CG1 . VAL   A 1 86  ? -4.36120  -26.98360 -18.29198 1.000 34.87387 ?  86  VAL   A CG1 1 
ATOM   664  C CG2 . VAL   A 1 86  ? -4.19164  -25.04932 -16.71689 1.000 29.91198 ?  86  VAL   A CG2 1 
ATOM   665  N N   . LEU   A 1 87  ? -3.77778  -29.44330 -16.38175 1.000 26.43167 ?  87  LEU   A N   1 
ATOM   666  C CA  . LEU   A 1 87  ? -3.84964  -30.77994 -16.93081 1.000 23.07131 ?  87  LEU   A CA  1 
ATOM   667  C C   . LEU   A 1 87  ? -4.67850  -30.74254 -18.20714 1.000 27.78361 ?  87  LEU   A C   1 
ATOM   668  O O   . LEU   A 1 87  ? -5.71003  -30.05636 -18.27501 1.000 25.37828 ?  87  LEU   A O   1 
ATOM   669  C CB  . LEU   A 1 87  ? -4.46314  -31.70769 -15.88096 1.000 24.60865 ?  87  LEU   A CB  1 
ATOM   670  C CG  . LEU   A 1 87  ? -4.65924  -33.17121 -16.20635 1.000 31.18511 ?  87  LEU   A CG  1 
ATOM   671  C CD1 . LEU   A 1 87  ? -3.31022  -33.87875 -16.34406 1.000 34.21285 ?  87  LEU   A CD1 1 
ATOM   672  C CD2 . LEU   A 1 87  ? -5.45823  -33.72850 -15.05578 1.000 32.56057 ?  87  LEU   A CD2 1 
ATOM   673  N N   . LYS   A 1 88  ? -4.17511  -31.41716 -19.24179 1.000 24.18263 ?  88  LYS   A N   1 
ATOM   674  C CA  . LYS   A 1 88  ? -4.86939  -31.58521 -20.50720 1.000 25.23383 ?  88  LYS   A CA  1 
ATOM   675  C C   . LYS   A 1 88  ? -5.23382  -33.05173 -20.64522 1.000 27.30990 ?  88  LYS   A C   1 
ATOM   676  O O   . LYS   A 1 88  ? -4.35610  -33.91725 -20.58139 1.000 27.98870 ?  88  LYS   A O   1 
ATOM   677  C CB  . LYS   A 1 88  ? -3.99795  -31.16079 -21.67951 1.000 27.29341 ?  88  LYS   A CB  1 
ATOM   678  C CG  . LYS   A 1 88  ? -3.70219  -29.67299 -21.70562 1.000 28.66983 ?  88  LYS   A CG  1 
ATOM   679  C CD  . LYS   A 1 88  ? -2.89507  -29.30312 -22.93034 1.000 30.53834 ?  88  LYS   A CD  1 
ATOM   680  C CE  . LYS   A 1 88  ? -1.47101  -29.76800 -22.80005 1.000 35.76561 ?  88  LYS   A CE  1 
ATOM   681  N NZ  . LYS   A 1 88  ? -0.62091  -29.19194 -23.88361 1.000 39.12626 ?  88  LYS   A NZ  1 
ATOM   682  N N   . LEU   A 1 89  ? -6.51392  -33.32445 -20.85953 1.000 27.88912 ?  89  LEU   A N   1 
ATOM   683  C CA  . LEU   A 1 89  ? -7.00238  -34.68624 -20.98997 1.000 24.10050 ?  89  LEU   A CA  1 
ATOM   684  C C   . LEU   A 1 89  ? -7.59367  -34.81996 -22.37774 1.000 25.75970 ?  89  LEU   A C   1 
ATOM   685  O O   . LEU   A 1 89  ? -8.56797  -34.13566 -22.70535 1.000 25.77447 ?  89  LEU   A O   1 
ATOM   686  C CB  . LEU   A 1 89  ? -8.04727  -34.99822 -19.91266 1.000 25.15108 ?  89  LEU   A CB  1 
ATOM   687  C CG  . LEU   A 1 89  ? -7.66142  -34.72524 -18.46031 1.000 22.86766 ?  89  LEU   A CG  1 
ATOM   688  C CD1 . LEU   A 1 89  ? -8.84122  -34.88529 -17.50874 1.000 27.56320 ?  89  LEU   A CD1 1 
ATOM   689  C CD2 . LEU   A 1 89  ? -6.52830  -35.63521 -18.01177 1.000 29.49848 ?  89  LEU   A CD2 1 
ATOM   690  N N   . LYS   A 1 90  ? -6.97818  -35.64949 -23.21636 1.000 22.93917 ?  90  LYS   A N   1 
ATOM   691  C CA  . LYS   A 1 90  ? -7.57598  -35.94602 -24.50234 1.000 24.58836 ?  90  LYS   A CA  1 
ATOM   692  C C   . LYS   A 1 90  ? -8.73183  -36.90447 -24.26967 1.000 21.81451 ?  90  LYS   A C   1 
ATOM   693  O O   . LYS   A 1 90  ? -8.55795  -37.92671 -23.59685 1.000 26.83723 ?  90  LYS   A O   1 
ATOM   694  C CB  . LYS   A 1 90  ? -6.54413  -36.56381 -25.44737 1.000 29.99735 ?  90  LYS   A CB  1 
ATOM   695  C CG  . LYS   A 1 90  ? -6.98067  -36.60690 -26.91756 1.000 30.67065 ?  90  LYS   A CG  1 
ATOM   696  C CD  . LYS   A 1 90  ? -5.87115  -36.01732 -27.77665 1.000 40.93951 ?  90  LYS   A CD  1 
ATOM   697  C CE  . LYS   A 1 90  ? -5.93205  -36.48713 -29.21569 1.000 49.29328 ?  90  LYS   A CE  1 
ATOM   698  N NZ  . LYS   A 1 90  ? -4.57041  -36.94983 -29.63661 1.000 49.73728 ?  90  LYS   A NZ  1 
ATOM   699  N N   . VAL   A 1 91  ? -9.88856  -36.59084 -24.86409 1.000 27.51185 ?  91  VAL   A N   1 
ATOM   700  C CA  . VAL   A 1 91  ? -11.09036 -37.40389 -24.75289 1.000 24.47415 ?  91  VAL   A CA  1 
ATOM   701  C C   . VAL   A 1 91  ? -11.48005 -37.89217 -26.14605 1.000 24.97027 ?  91  VAL   A C   1 
ATOM   702  O O   . VAL   A 1 91  ? -10.96332 -37.43156 -27.15934 1.000 23.98857 ?  91  VAL   A O   1 
ATOM   703  C CB  . VAL   A 1 91  ? -12.25780 -36.65108 -24.07051 1.000 24.90621 ?  91  VAL   A CB  1 
ATOM   704  C CG1 . VAL   A 1 91  ? -11.89685 -36.36474 -22.60776 1.000 25.60697 ?  91  VAL   A CG1 1 
ATOM   705  C CG2 . VAL   A 1 91  ? -12.58449 -35.36290 -24.80063 1.000 21.56408 ?  91  VAL   A CG2 1 
ATOM   706  N N   . ASP   A 1 92  ? -12.36644 -38.88407 -26.18125 1.000 25.17221 ?  92  ASP   A N   1 
ATOM   707  C CA  . ASP   A 1 92  ? -12.65212 -39.53725 -27.45230 1.000 26.42937 ?  92  ASP   A CA  1 
ATOM   708  C C   . ASP   A 1 92  ? -13.79206 -38.89072 -28.22016 1.000 32.20017 ?  92  ASP   A C   1 
ATOM   709  O O   . ASP   A 1 92  ? -14.23914 -39.45083 -29.23462 1.000 30.60495 ?  92  ASP   A O   1 
ATOM   710  C CB  . ASP   A 1 92  ? -12.93939 -41.02696 -27.22070 1.000 31.64257 ?  92  ASP   A CB  1 
ATOM   711  C CG  . ASP   A 1 92  ? -14.27345 -41.28540 -26.52838 1.000 34.51240 ?  92  ASP   A CG  1 
ATOM   712  O OD1 . ASP   A 1 92  ? -14.97728 -40.33490 -26.11575 1.000 36.54722 ?  92  ASP   A OD1 1 
ATOM   713  O OD2 . ASP   A 1 92  ? -14.62351 -42.48530 -26.39343 1.000 39.38881 -1 92  ASP   A OD2 1 
ATOM   714  N N   . THR   A 1 93  ? -14.27513 -37.73896 -27.77101 1.000 27.03310 ?  93  THR   A N   1 
ATOM   715  C CA  . THR   A 1 93  ? -15.39532 -37.07462 -28.42451 1.000 27.07415 ?  93  THR   A CA  1 
ATOM   716  C C   . THR   A 1 93  ? -15.01533 -35.61843 -28.63273 1.000 27.08826 ?  93  THR   A C   1 
ATOM   717  O O   . THR   A 1 93  ? -14.53834 -34.97962 -27.69452 1.000 25.80153 ?  93  THR   A O   1 
ATOM   718  C CB  . THR   A 1 93  ? -16.65900 -37.16456 -27.55178 1.000 26.40352 ?  93  THR   A CB  1 
ATOM   719  O OG1 . THR   A 1 93  ? -16.93035 -38.53605 -27.25088 1.000 30.46001 ?  93  THR   A OG1 1 
ATOM   720  C CG2 . THR   A 1 93  ? -17.85593 -36.54023 -28.23960 1.000 27.97341 ?  93  THR   A CG2 1 
ATOM   721  N N   . ALA   A 1 94  ? -15.19837 -35.10148 -29.85084 1.000 26.31214 ?  94  ALA   A N   1 
ATOM   722  C CA  . ALA   A 1 94  ? -14.96300 -33.68359 -30.09270 1.000 26.74080 ?  94  ALA   A CA  1 
ATOM   723  C C   . ALA   A 1 94  ? -16.21602 -32.92052 -29.70734 1.000 26.80898 ?  94  ALA   A C   1 
ATOM   724  O O   . ALA   A 1 94  ? -17.32032 -33.31048 -30.09397 1.000 24.89081 ?  94  ALA   A O   1 
ATOM   725  C CB  . ALA   A 1 94  ? -14.60827 -33.42176 -31.56198 1.000 27.11868 ?  94  ALA   A CB  1 
ATOM   726  N N   . ASN   A 1 95  ? -16.05671 -31.85372 -28.92679 1.000 22.65726 ?  95  ASN   A N   1 
ATOM   727  C CA  . ASN   A 1 95  ? -17.22952 -31.13959 -28.44383 1.000 24.08232 ?  95  ASN   A CA  1 
ATOM   728  C C   . ASN   A 1 95  ? -17.95367 -30.46484 -29.59758 1.000 24.58740 ?  95  ASN   A C   1 
ATOM   729  O O   . ASN   A 1 95  ? -17.39909 -29.53530 -30.20230 1.000 24.75290 ?  95  ASN   A O   1 
ATOM   730  C CB  . ASN   A 1 95  ? -16.81547 -30.09362 -27.38346 1.000 22.87832 ?  95  ASN   A CB  1 
ATOM   731  C CG  . ASN   A 1 95  ? -17.99316 -29.35286 -26.80788 1.000 23.58094 ?  95  ASN   A CG  1 
ATOM   732  O OD1 . ASN   A 1 95  ? -19.14550 -29.59191 -27.18183 1.000 25.65456 ?  95  ASN   A OD1 1 
ATOM   733  N ND2 . ASN   A 1 95  ? -17.71729 -28.44761 -25.87657 1.000 24.24668 ?  95  ASN   A ND2 1 
ATOM   734  N N   . PRO   A 1 96  ? -19.18528 -30.86216 -29.91728 1.000 24.55618 ?  96  PRO   A N   1 
ATOM   735  C CA  . PRO   A 1 96  ? -19.88675 -30.23679 -31.04481 1.000 25.58417 ?  96  PRO   A CA  1 
ATOM   736  C C   . PRO   A 1 96  ? -20.24383 -28.77745 -30.80403 1.000 26.92065 ?  96  PRO   A C   1 
ATOM   737  O O   . PRO   A 1 96  ? -20.59963 -28.07863 -31.76880 1.000 26.76813 ?  96  PRO   A O   1 
ATOM   738  C CB  . PRO   A 1 96  ? -21.15454 -31.10067 -31.19648 1.000 26.43484 ?  96  PRO   A CB  1 
ATOM   739  C CG  . PRO   A 1 96  ? -20.87442 -32.37782 -30.41693 1.000 26.83462 ?  96  PRO   A CG  1 
ATOM   740  C CD  . PRO   A 1 96  ? -19.98537 -31.92068 -29.27668 1.000 26.03345 ?  96  PRO   A CD  1 
ATOM   741  N N   . LYS   A 1 97  ? -20.19121 -28.31128 -29.55798 1.000 24.54245 ?  97  LYS   A N   1 
ATOM   742  C CA  . LYS   A 1 97  ? -20.46790 -26.91607 -29.22861 1.000 26.19769 ?  97  LYS   A CA  1 
ATOM   743  C C   . LYS   A 1 97  ? -19.20072 -26.07290 -29.12516 1.000 26.57543 ?  97  LYS   A C   1 
ATOM   744  O O   . LYS   A 1 97  ? -19.26192 -24.93624 -28.64759 1.000 25.20263 ?  97  LYS   A O   1 
ATOM   745  C CB  . LYS   A 1 97  ? -21.24921 -26.83746 -27.91392 1.000 28.89879 ?  97  LYS   A CB  1 
ATOM   746  C CG  . LYS   A 1 97  ? -22.58093 -27.58447 -27.91339 1.000 33.36221 ?  97  LYS   A CG  1 
ATOM   747  C CD  . LYS   A 1 97  ? -23.29816 -27.37070 -26.58441 1.000 39.33804 ?  97  LYS   A CD  1 
ATOM   748  C CE  . LYS   A 1 97  ? -24.24424 -28.52096 -26.24901 1.000 45.67575 ?  97  LYS   A CE  1 
ATOM   749  N NZ  . LYS   A 1 97  ? -25.59986 -28.33432 -26.85115 1.000 50.98146 ?  97  LYS   A NZ  1 
ATOM   750  N N   . THR   A 1 98  ? -18.05365 -26.59897 -29.53095 1.000 26.23935 ?  98  THR   A N   1 
ATOM   751  C CA  . THR   A 1 98  ? -16.82788 -25.81365 -29.50955 1.000 26.04921 ?  98  THR   A CA  1 
ATOM   752  C C   . THR   A 1 98  ? -17.01477 -24.53497 -30.31345 1.000 30.40680 ?  98  THR   A C   1 
ATOM   753  O O   . THR   A 1 98  ? -17.39744 -24.60568 -31.49086 1.000 26.86417 ?  98  THR   A O   1 
ATOM   754  C CB  . THR   A 1 98  ? -15.66197 -26.60245 -30.08908 1.000 27.54352 ?  98  THR   A CB  1 
ATOM   755  O OG1 . THR   A 1 98  ? -15.54270 -27.84754 -29.39738 1.000 26.16302 ?  98  THR   A OG1 1 
ATOM   756  C CG2 . THR   A 1 98  ? -14.36137 -25.84087 -29.90029 1.000 28.01089 ?  98  THR   A CG2 1 
ATOM   757  N N   . PRO   A 1 99  ? -16.78344 -23.36621 -29.73255 1.000 24.42565 ?  99  PRO   A N   1 
ATOM   758  C CA  . PRO   A 1 99  ? -16.85034 -22.12861 -30.51084 1.000 27.15315 ?  99  PRO   A CA  1 
ATOM   759  C C   . PRO   A 1 99  ? -15.51023 -21.89353 -31.18141 1.000 26.79734 ?  99  PRO   A C   1 
ATOM   760  O O   . PRO   A 1 99  ? -14.52395 -22.58612 -30.92770 1.000 27.58898 ?  99  PRO   A O   1 
ATOM   761  C CB  . PRO   A 1 99  ? -17.13810 -21.06707 -29.44758 1.000 27.92908 ?  99  PRO   A CB  1 
ATOM   762  C CG  . PRO   A 1 99  ? -16.39114 -21.59242 -28.23136 1.000 25.92482 ?  99  PRO   A CG  1 
ATOM   763  C CD  . PRO   A 1 99  ? -16.50674 -23.10802 -28.30787 1.000 25.08021 ?  99  PRO   A CD  1 
ATOM   764  N N   . LYS   A 1 100 ? -15.46479 -20.88416 -32.04424 1.000 26.72014 ?  100 LYS   A N   1 
ATOM   765  C CA  . LYS   A 1 100 ? -14.14682 -20.42228 -32.43536 1.000 27.71842 ?  100 LYS   A CA  1 
ATOM   766  C C   . LYS   A 1 100 ? -13.49644 -19.81197 -31.20810 1.000 28.22984 ?  100 LYS   A C   1 
ATOM   767  O O   . LYS   A 1 100 ? -14.15476 -19.10141 -30.44260 1.000 29.42214 ?  100 LYS   A O   1 
ATOM   768  C CB  . LYS   A 1 100 ? -14.23360 -19.41196 -33.57272 1.000 33.89125 ?  100 LYS   A CB  1 
ATOM   769  C CG  . LYS   A 1 100 ? -14.83598 -20.06081 -34.81752 1.000 37.05307 ?  100 LYS   A CG  1 
ATOM   770  C CD  . LYS   A 1 100 ? -14.84963 -19.14608 -36.01718 1.000 45.75709 ?  100 LYS   A CD  1 
ATOM   771  C CE  . LYS   A 1 100 ? -16.15091 -18.40628 -36.07515 1.000 50.63638 ?  100 LYS   A CE  1 
ATOM   772  N NZ  . LYS   A 1 100 ? -16.44150 -17.80354 -34.75440 1.000 49.55511 ?  100 LYS   A NZ  1 
ATOM   773  N N   . TYR   A 1 101 ? -12.22637 -20.12213 -30.99236 1.000 26.71288 ?  101 TYR   A N   1 
ATOM   774  C CA  . TYR   A 1 101 ? -11.58840 -19.68558 -29.75425 1.000 30.21905 ?  101 TYR   A CA  1 
ATOM   775  C C   . TYR   A 1 101 ? -10.09074 -19.47752 -29.92212 1.000 29.98133 ?  101 TYR   A C   1 
ATOM   776  O O   . TYR   A 1 101 ? -9.45720  -19.93763 -30.87915 1.000 31.72952 ?  101 TYR   A O   1 
ATOM   777  C CB  . TYR   A 1 101 ? -11.82386 -20.68018 -28.60377 1.000 28.31986 ?  101 TYR   A CB  1 
ATOM   778  C CG  . TYR   A 1 101 ? -11.04304 -21.96576 -28.75640 1.000 28.00069 ?  101 TYR   A CG  1 
ATOM   779  C CD1 . TYR   A 1 101 ? -11.56700 -23.01584 -29.49905 1.000 31.88052 ?  101 TYR   A CD1 1 
ATOM   780  C CD2 . TYR   A 1 101 ? -9.79448  -22.13772 -28.17381 1.000 29.07224 ?  101 TYR   A CD2 1 
ATOM   781  C CE1 . TYR   A 1 101 ? -10.87518 -24.19612 -29.65906 1.000 32.45509 ?  101 TYR   A CE1 1 
ATOM   782  C CE2 . TYR   A 1 101 ? -9.09318  -23.34701 -28.33174 1.000 30.33297 ?  101 TYR   A CE2 1 
ATOM   783  C CZ  . TYR   A 1 101 ? -9.65430  -24.35599 -29.08059 1.000 34.32568 ?  101 TYR   A CZ  1 
ATOM   784  O OH  . TYR   A 1 101 ? -9.00821  -25.57042 -29.27785 1.000 44.63976 ?  101 TYR   A OH  1 
ATOM   785  N N   . LYS   A 1 102 ? -9.52520  -18.81940 -28.91762 1.000 27.70821 ?  102 LYS   A N   1 
ATOM   786  C CA  . LYS   A 1 102 ? -8.10941  -18.54012 -28.80938 1.000 28.10588 ?  102 LYS   A CA  1 
ATOM   787  C C   . LYS   A 1 102 ? -7.77291  -18.48618 -27.32498 1.000 28.88739 ?  102 LYS   A C   1 
ATOM   788  O O   . LYS   A 1 102 ? -8.64790  -18.19440 -26.50144 1.000 26.22012 ?  102 LYS   A O   1 
ATOM   789  C CB  . LYS   A 1 102 ? -7.80484  -17.22679 -29.54404 1.000 36.06295 ?  102 LYS   A CB  1 
ATOM   790  C CG  . LYS   A 1 102 ? -6.62373  -16.43129 -29.08257 1.000 39.30795 ?  102 LYS   A CG  1 
ATOM   791  C CD  . LYS   A 1 102 ? -6.79397  -14.98679 -29.60518 1.000 42.55125 ?  102 LYS   A CD  1 
ATOM   792  C CE  . LYS   A 1 102 ? -7.20909  -14.98332 -31.06665 1.000 44.16691 ?  102 LYS   A CE  1 
ATOM   793  N NZ  . LYS   A 1 102 ? -8.17383  -13.89129 -31.38900 1.000 52.70965 ?  102 LYS   A NZ  1 
ATOM   794  N N   . PHE   A 1 103 ? -6.53124  -18.83044 -26.98519 1.000 24.74362 ?  103 PHE   A N   1 
ATOM   795  C CA  . PHE   A 1 103 ? -5.99599  -18.67014 -25.63364 1.000 26.64002 ?  103 PHE   A CA  1 
ATOM   796  C C   . PHE   A 1 103 ? -5.15084  -17.40677 -25.56555 1.000 30.34923 ?  103 PHE   A C   1 
ATOM   797  O O   . PHE   A 1 103 ? -4.22281  -17.24518 -26.35818 1.000 30.85689 ?  103 PHE   A O   1 
ATOM   798  C CB  . PHE   A 1 103 ? -5.12016  -19.85709 -25.22464 1.000 27.93983 ?  103 PHE   A CB  1 
ATOM   799  C CG  . PHE   A 1 103 ? -5.87975  -21.13875 -24.98944 1.000 26.74895 ?  103 PHE   A CG  1 
ATOM   800  C CD1 . PHE   A 1 103 ? -7.26609  -21.15533 -24.96807 1.000 28.35732 ?  103 PHE   A CD1 1 
ATOM   801  C CD2 . PHE   A 1 103 ? -5.19116  -22.32449 -24.77969 1.000 28.72785 ?  103 PHE   A CD2 1 
ATOM   802  C CE1 . PHE   A 1 103 ? -7.95582  -22.33917 -24.74236 1.000 27.46183 ?  103 PHE   A CE1 1 
ATOM   803  C CE2 . PHE   A 1 103 ? -5.87599  -23.50704 -24.54985 1.000 28.55604 ?  103 PHE   A CE2 1 
ATOM   804  C CZ  . PHE   A 1 103 ? -7.25349  -23.50758 -24.52861 1.000 27.94331 ?  103 PHE   A CZ  1 
ATOM   805  N N   . VAL   A 1 104 ? -5.44348  -16.53045 -24.60467 1.000 27.90618 ?  104 VAL   A N   1 
ATOM   806  C CA  . VAL   A 1 104 ? -4.70682  -15.27787 -24.46919 1.000 26.78219 ?  104 VAL   A CA  1 
ATOM   807  C C   . VAL   A 1 104 ? -4.22674  -15.11485 -23.03843 1.000 30.23599 ?  104 VAL   A C   1 
ATOM   808  O O   . VAL   A 1 104 ? -4.83995  -15.60137 -22.08239 1.000 29.22409 ?  104 VAL   A O   1 
ATOM   809  C CB  . VAL   A 1 104 ? -5.54509  -14.04742 -24.87543 1.000 27.76109 ?  104 VAL   A CB  1 
ATOM   810  C CG1 . VAL   A 1 104 ? -6.14759  -14.20515 -26.25664 1.000 33.48150 ?  104 VAL   A CG1 1 
ATOM   811  C CG2 . VAL   A 1 104 ? -6.61662  -13.78575 -23.85436 1.000 33.86766 ?  104 VAL   A CG2 1 
ATOM   812  N N   . ARG   A 1 105 ? -3.11851  -14.41301 -22.88656 1.000 28.89262 ?  105 ARG   A N   1 
ATOM   813  C CA  . ARG   A 1 105 ? -2.65264  -14.00259 -21.57192 1.000 25.28056 ?  105 ARG   A CA  1 
ATOM   814  C C   . ARG   A 1 105 ? -2.90859  -12.50677 -21.47273 1.000 28.28467 ?  105 ARG   A C   1 
ATOM   815  O O   . ARG   A 1 105 ? -2.34051  -11.73727 -22.24849 1.000 28.73095 ?  105 ARG   A O   1 
ATOM   816  C CB  . ARG   A 1 105 ? -1.17442  -14.31915 -21.36995 1.000 29.71245 ?  105 ARG   A CB  1 
ATOM   817  C CG  . ARG   A 1 105 ? -0.69655  -14.11344 -19.94368 1.000 28.96882 ?  105 ARG   A CG  1 
ATOM   818  C CD  . ARG   A 1 105 ? 0.74432   -14.59830 -19.75364 1.000 31.47876 ?  105 ARG   A CD  1 
ATOM   819  N NE  . ARG   A 1 105 ? 1.26394   -14.29813 -18.42751 1.000 29.99932 ?  105 ARG   A NE  1 
ATOM   820  C CZ  . ARG   A 1 105 ? 0.95145   -14.97851 -17.33355 1.000 29.08475 ?  105 ARG   A CZ  1 
ATOM   821  N NH1 . ARG   A 1 105 ? 0.08462   -15.97887 -17.36954 1.000 28.90340 ?  105 ARG   A NH1 1 
ATOM   822  N NH2 . ARG   A 1 105 ? 1.52349   -14.65295 -16.17548 1.000 30.50493 ?  105 ARG   A NH2 1 
ATOM   823  N N   . ILE   A 1 106 ? -3.76121  -12.09368 -20.53005 1.000 26.15478 ?  106 ILE   A N   1 
ATOM   824  C CA  . ILE   A 1 106 ? -4.14320  -10.68256 -20.47862 1.000 27.50564 ?  106 ILE   A CA  1 
ATOM   825  C C   . ILE   A 1 106 ? -3.17282  -9.88745  -19.61865 1.000 27.71830 ?  106 ILE   A C   1 
ATOM   826  O O   . ILE   A 1 106 ? -2.37797  -10.45040 -18.86869 1.000 29.35017 ?  106 ILE   A O   1 
ATOM   827  C CB  . ILE   A 1 106 ? -5.57876  -10.50656 -19.96583 1.000 25.69474 ?  106 ILE   A CB  1 
ATOM   828  C CG1 . ILE   A 1 106 ? -5.73733  -11.18491 -18.61075 1.000 28.26073 ?  106 ILE   A CG1 1 
ATOM   829  C CG2 . ILE   A 1 106 ? -6.57697  -11.03447 -21.01962 1.000 27.16797 ?  106 ILE   A CG2 1 
ATOM   830  C CD1 . ILE   A 1 106 ? -7.02738  -10.79156 -17.88008 1.000 32.81592 ?  106 ILE   A CD1 1 
ATOM   831  N N   . GLN   A 1 107 ? -3.24393  -8.51228  -19.72219 1.000 28.24120 ?  107 GLN   A N   1 
ATOM   832  C CA  . GLN   A 1 107 ? -2.48838  -7.54068  -18.94807 1.000 28.08217 ?  107 GLN   A CA  1 
ATOM   833  C C   . GLN   A 1 107 ? -3.27695  -7.11813  -17.71327 1.000 25.79170 ?  107 GLN   A C   1 
ATOM   834  O O   . GLN   A 1 107 ? -4.50809  -7.15445  -17.72400 1.000 27.49235 ?  107 GLN   A O   1 
ATOM   835  C CB  . GLN   A 1 107 ? -2.20375  -6.29853  -19.79726 1.000 30.57861 ?  107 GLN   A CB  1 
ATOM   836  C CG  . GLN   A 1 107 ? -1.14575  -6.47601  -20.83454 1.000 35.11912 ?  107 GLN   A CG  1 
ATOM   837  C CD  . GLN   A 1 107 ? 0.19344   -6.83665  -20.21229 1.000 36.75970 ?  107 GLN   A CD  1 
ATOM   838  O OE1 . GLN   A 1 107 ? 0.55655   -8.00819  -20.19950 1.000 38.24852 ?  107 GLN   A OE1 1 
ATOM   839  N NE2 . GLN   A 1 107 ? 0.93627   -5.82851  -19.68885 1.000 34.37900 ?  107 GLN   A NE2 1 
ATOM   840  N N   . PRO   A 1 108 ? -2.62136  -6.70035  -16.63143 1.000 30.23029 ?  108 PRO   A N   1 
ATOM   841  C CA  . PRO   A 1 108 ? -3.35544  -6.01793  -15.56164 1.000 30.79508 ?  108 PRO   A CA  1 
ATOM   842  C C   . PRO   A 1 108 ? -4.15398  -4.87039  -16.14884 1.000 30.24062 ?  108 PRO   A C   1 
ATOM   843  O O   . PRO   A 1 108 ? -3.71590  -4.21491  -17.09602 1.000 31.35541 ?  108 PRO   A O   1 
ATOM   844  C CB  . PRO   A 1 108 ? -2.24715  -5.50012  -14.63469 1.000 32.13393 ?  108 PRO   A CB  1 
ATOM   845  C CG  . PRO   A 1 108 ? -1.07929  -6.28389  -14.95248 1.000 33.23555 ?  108 PRO   A CG  1 
ATOM   846  C CD  . PRO   A 1 108 ? -1.16791  -6.64949  -16.39892 1.000 32.28490 ?  108 PRO   A CD  1 
ATOM   847  N N   . GLY   A 1 109 ? -5.34159  -4.63481  -15.58344 1.000 27.82878 ?  109 GLY   A N   1 
ATOM   848  C CA  . GLY   A 1 109 ? -6.26851  -3.65189  -16.08067 1.000 27.48935 ?  109 GLY   A CA  1 
ATOM   849  C C   . GLY   A 1 109 ? -7.31480  -4.21983  -17.00156 1.000 31.69101 ?  109 GLY   A C   1 
ATOM   850  O O   . GLY   A 1 109 ? -8.42124  -3.68593  -17.07040 1.000 32.31822 ?  109 GLY   A O   1 
ATOM   851  N N   . GLN   A 1 110 ? -6.99202  -5.29207  -17.71966 1.000 25.67385 ?  110 GLN   A N   1 
ATOM   852  C CA  . GLN   A 1 110 ? -7.94218  -5.82349  -18.67236 1.000 27.49028 ?  110 GLN   A CA  1 
ATOM   853  C C   . GLN   A 1 110 ? -9.07190  -6.51034  -17.92848 1.000 27.06740 ?  110 GLN   A C   1 
ATOM   854  O O   . GLN   A 1 110 ? -8.86595  -7.14572  -16.89165 1.000 28.83497 ?  110 GLN   A O   1 
ATOM   855  C CB  . GLN   A 1 110 ? -7.24590  -6.79467  -19.61785 1.000 30.26633 ?  110 GLN   A CB  1 
ATOM   856  C CG  . GLN   A 1 110 ? -6.24902  -6.09888  -20.55456 1.000 32.21877 ?  110 GLN   A CG  1 
ATOM   857  C CD  . GLN   A 1 110 ? -5.92937  -6.94544  -21.78074 1.000 33.79791 ?  110 GLN   A CD  1 
ATOM   858  O OE1 . GLN   A 1 110 ? -4.87198  -7.54863  -21.87302 1.000 31.77556 ?  110 GLN   A OE1 1 
ATOM   859  N NE2 . GLN   A 1 110 ? -6.86817  -6.99762  -22.72322 1.000 46.82472 ?  110 GLN   A NE2 1 
ATOM   860  N N   . THR   A 1 111 ? -10.26859 -6.39439  -18.47760 1.000 26.88506 ?  111 THR   A N   1 
ATOM   861  C CA  . THR   A 1 111 ? -11.43412 -6.99634  -17.86011 1.000 28.27576 ?  111 THR   A CA  1 
ATOM   862  C C   . THR   A 1 111 ? -11.81043 -8.26489  -18.60356 1.000 26.27142 ?  111 THR   A C   1 
ATOM   863  O O   . THR   A 1 111 ? -11.38086 -8.50219  -19.73246 1.000 28.50419 ?  111 THR   A O   1 
ATOM   864  C CB  . THR   A 1 111 ? -12.61819 -6.04006  -17.84301 1.000 29.84054 ?  111 THR   A CB  1 
ATOM   865  O OG1 . THR   A 1 111 ? -12.90760 -5.58897  -19.18023 1.000 28.03498 ?  111 THR   A OG1 1 
ATOM   866  C CG2 . THR   A 1 111 ? -12.31305 -4.83753  -16.92029 1.000 28.43232 ?  111 THR   A CG2 1 
ATOM   867  N N   . PHE   A 1 112 ? -12.61455 -9.08110  -17.93916 1.000 24.70766 ?  112 PHE   A N   1 
ATOM   868  C CA  . PHE   A 1 112 ? -13.12040 -10.29545 -18.56234 1.000 25.91244 ?  112 PHE   A CA  1 
ATOM   869  C C   . PHE   A 1 112 ? -14.34150 -10.77414 -17.79549 1.000 25.45937 ?  112 PHE   A C   1 
ATOM   870  O O   . PHE   A 1 112 ? -14.56787 -10.38116 -16.64537 1.000 24.66038 ?  112 PHE   A O   1 
ATOM   871  C CB  . PHE   A 1 112 ? -12.04961 -11.39419 -18.62915 1.000 26.37876 ?  112 PHE   A CB  1 
ATOM   872  C CG  . PHE   A 1 112 ? -11.39397 -11.71453 -17.30201 1.000 26.60806 ?  112 PHE   A CG  1 
ATOM   873  C CD1 . PHE   A 1 112 ? -10.32509 -10.96333 -16.84589 1.000 27.02517 ?  112 PHE   A CD1 1 
ATOM   874  C CD2 . PHE   A 1 112 ? -11.83057 -12.78284 -16.52978 1.000 24.14322 ?  112 PHE   A CD2 1 
ATOM   875  C CE1 . PHE   A 1 112 ? -9.69456  -11.27645 -15.63897 1.000 27.56664 ?  112 PHE   A CE1 1 
ATOM   876  C CE2 . PHE   A 1 112 ? -11.21189 -13.08972 -15.31046 1.000 25.62324 ?  112 PHE   A CE2 1 
ATOM   877  C CZ  . PHE   A 1 112 ? -10.14432 -12.34549 -14.87507 1.000 26.56826 ?  112 PHE   A CZ  1 
ATOM   878  N N   . SER   A 1 113 ? -15.14242 -11.61825 -18.45634 1.000 22.57457 ?  113 SER   A N   1 
ATOM   879  C CA  . SER   A 1 113 ? -16.29546 -12.24916 -17.82447 1.000 19.69878 ?  113 SER   A CA  1 
ATOM   880  C C   . SER   A 1 113 ? -15.85519 -13.55792 -17.18169 1.000 22.99693 ?  113 SER   A C   1 
ATOM   881  O O   . SER   A 1 113 ? -15.07946 -14.30207 -17.76608 1.000 23.06365 ?  113 SER   A O   1 
ATOM   882  C CB  . SER   A 1 113 ? -17.38644 -12.53376 -18.85268 1.000 21.74426 ?  113 SER   A CB  1 
ATOM   883  O OG  . SER   A 1 113 ? -17.84610 -11.29010 -19.37077 1.000 24.79747 ?  113 SER   A OG  1 
ATOM   884  N N   . VAL   A 1 114 ? -16.35070 -13.83214 -15.98336 1.000 21.69806 ?  114 VAL   A N   1 
ATOM   885  C CA  . VAL   A 1 114 ? -16.11878 -15.11333 -15.31701 1.000 21.33935 ?  114 VAL   A CA  1 
ATOM   886  C C   . VAL   A 1 114 ? -17.41763 -15.89448 -15.31966 1.000 21.49520 ?  114 VAL   A C   1 
ATOM   887  O O   . VAL   A 1 114 ? -18.47537 -15.36573 -14.93239 1.000 21.91886 ?  114 VAL   A O   1 
ATOM   888  C CB  . VAL   A 1 114 ? -15.61687 -14.91527 -13.88113 1.000 23.52384 ?  114 VAL   A CB  1 
ATOM   889  C CG1 . VAL   A 1 114 ? -15.66854 -16.26016 -13.13802 1.000 23.78047 ?  114 VAL   A CG1 1 
ATOM   890  C CG2 . VAL   A 1 114 ? -14.22350 -14.34044 -13.91041 1.000 26.36634 ?  114 VAL   A CG2 1 
ATOM   891  N N   . LEU   A 1 115 ? -17.34500 -17.16172 -15.74981 1.000 20.54464 ?  115 LEU   A N   1 
ATOM   892  C CA  . LEU   A 1 115 ? -18.49248 -18.05465 -15.61998 1.000 20.45188 ?  115 LEU   A CA  1 
ATOM   893  C C   . LEU   A 1 115 ? -18.18919 -18.97324 -14.44854 1.000 22.08141 ?  115 LEU   A C   1 
ATOM   894  O O   . LEU   A 1 115 ? -17.41452 -19.93393 -14.57829 1.000 23.86663 ?  115 LEU   A O   1 
ATOM   895  C CB  . LEU   A 1 115 ? -18.76477 -18.82575 -16.90833 1.000 20.44990 ?  115 LEU   A CB  1 
ATOM   896  C CG  . LEU   A 1 115 ? -19.94714 -19.78807 -16.85081 1.000 21.67532 ?  115 LEU   A CG  1 
ATOM   897  C CD1 . LEU   A 1 115 ? -21.30895 -19.05838 -16.78337 1.000 22.95812 ?  115 LEU   A CD1 1 
ATOM   898  C CD2 . LEU   A 1 115 ? -19.91525 -20.70987 -18.07996 1.000 24.58788 ?  115 LEU   A CD2 1 
ATOM   899  N N   . ALA   A 1 116 ? -18.79410 -18.66253 -13.29287 1.000 21.09375 ?  116 ALA   A N   1 
ATOM   900  C CA  . ALA   A 1 116 ? -18.62172 -19.45501 -12.08110 1.000 21.27877 ?  116 ALA   A CA  1 
ATOM   901  C C   . ALA   A 1 116 ? -19.41939 -20.74650 -12.20046 1.000 23.10381 ?  116 ALA   A C   1 
ATOM   902  O O   . ALA   A 1 116 ? -20.63843 -20.70864 -12.44836 1.000 27.04308 ?  116 ALA   A O   1 
ATOM   903  C CB  . ALA   A 1 116 ? -19.09179 -18.66169 -10.86550 1.000 21.71354 ?  116 ALA   A CB  1 
ATOM   904  N N   . CYS   A 1 117 ? -18.72750 -21.88136 -12.02308 1.000 20.90650 ?  117 CYS   A N   1 
ATOM   905  C CA  . CYS   A 1 117 ? -19.28250 -23.21021 -12.22751 1.000 22.62414 ?  117 CYS   A CA  1 
ATOM   906  C C   . CYS   A 1 117 ? -18.99895 -24.10705 -11.02918 1.000 22.97749 ?  117 CYS   A C   1 
ATOM   907  O O   . CYS   A 1 117 ? -17.98798 -23.95057 -10.33594 1.000 23.80083 ?  117 CYS   A O   1 
ATOM   908  C CB  . CYS   A 1 117 ? -18.68609 -23.90577 -13.47026 1.000 24.67397 ?  117 CYS   A CB  1 
ATOM   909  S SG  . CYS   A 1 117 ? -19.08832 -23.11324 -14.99293 1.000 29.81444 ?  117 CYS   A SG  1 
ATOM   910  N N   . TYR   A 1 118 ? -19.92209 -25.04406 -10.80546 1.000 26.19978 ?  118 TYR   A N   1 
ATOM   911  C CA  . TYR   A 1 118 ? -19.83471 -26.03940 -9.73944  1.000 28.70672 ?  118 TYR   A CA  1 
ATOM   912  C C   . TYR   A 1 118 ? -20.26511 -27.37145 -10.32186 1.000 27.43738 ?  118 TYR   A C   1 
ATOM   913  O O   . TYR   A 1 118 ? -21.32175 -27.46579 -10.94609 1.000 27.98444 ?  118 TYR   A O   1 
ATOM   914  C CB  . TYR   A 1 118 ? -20.69900 -25.63417 -8.52761  1.000 30.14693 ?  118 TYR   A CB  1 
ATOM   915  C CG  . TYR   A 1 118 ? -20.19380 -24.33266 -7.97565  1.000 26.66176 ?  118 TYR   A CG  1 
ATOM   916  C CD1 . TYR   A 1 118 ? -19.17203 -24.30639 -7.03707  1.000 24.58849 ?  118 TYR   A CD1 1 
ATOM   917  C CD2 . TYR   A 1 118 ? -20.68514 -23.11286 -8.45609  1.000 25.16738 ?  118 TYR   A CD2 1 
ATOM   918  C CE1 . TYR   A 1 118 ? -18.66645 -23.12893 -6.57157  1.000 25.09254 ?  118 TYR   A CE1 1 
ATOM   919  C CE2 . TYR   A 1 118 ? -20.19236 -21.92439 -7.99945  1.000 27.63619 ?  118 TYR   A CE2 1 
ATOM   920  C CZ  . TYR   A 1 118 ? -19.18197 -21.92672 -7.05685  1.000 23.21284 ?  118 TYR   A CZ  1 
ATOM   921  O OH  . TYR   A 1 118 ? -18.66434 -20.74831 -6.60209  1.000 27.87428 ?  118 TYR   A OH  1 
ATOM   922  N N   . ASN   A 1 119 ? -19.41885 -28.39069 -10.15993 1.000 29.58232 ?  119 ASN   A N   1 
ATOM   923  C CA  . ASN   A 1 119 ? -19.70881 -29.72259 -10.68494 1.000 31.40346 ?  119 ASN   A CA  1 
ATOM   924  C C   . ASN   A 1 119 ? -19.96632 -29.70264 -12.18875 1.000 29.72489 ?  119 ASN   A C   1 
ATOM   925  O O   . ASN   A 1 119 ? -20.78145 -30.47727 -12.70706 1.000 32.63932 ?  119 ASN   A O   1 
ATOM   926  C CB  . ASN   A 1 119 ? -20.89100 -30.35718 -9.94574  1.000 31.56561 ?  119 ASN   A CB  1 
ATOM   927  C CG  . ASN   A 1 119 ? -20.68933 -30.39105 -8.46051  1.000 36.40237 ?  119 ASN   A CG  1 
ATOM   928  O OD1 . ASN   A 1 119 ? -19.73117 -30.98319 -7.95325  1.000 41.45455 ?  119 ASN   A OD1 1 
ATOM   929  N ND2 . ASN   A 1 119 ? -21.57499 -29.71819 -7.74112  1.000 41.39547 ?  119 ASN   A ND2 1 
ATOM   930  N N   . GLY   A 1 120 ? -19.27334 -28.81984 -12.91102 1.000 25.46769 ?  120 GLY   A N   1 
ATOM   931  C CA  . GLY   A 1 120 ? -19.45567 -28.70526 -14.33986 1.000 25.94799 ?  120 GLY   A CA  1 
ATOM   932  C C   . GLY   A 1 120 ? -20.69922 -27.96482 -14.76244 1.000 31.55433 ?  120 GLY   A C   1 
ATOM   933  O O   . GLY   A 1 120 ? -20.99807 -27.92432 -15.96087 1.000 29.78504 ?  120 GLY   A O   1 
ATOM   934  N N   . SER   A 1 121 ? -21.43987 -27.38344 -13.82013 1.000 29.86814 ?  121 SER   A N   1 
ATOM   935  C CA  . SER   A 1 121 ? -22.70116 -26.72192 -14.13150 1.000 29.66121 ?  121 SER   A CA  1 
ATOM   936  C C   . SER   A 1 121 ? -22.54247 -25.22530 -13.94537 1.000 27.88168 ?  121 SER   A C   1 
ATOM   937  O O   . SER   A 1 121 ? -22.17890 -24.78234 -12.84901 1.000 25.07395 ?  121 SER   A O   1 
ATOM   938  C CB  . SER   A 1 121 ? -23.82089 -27.23617 -13.23683 1.000 33.87831 ?  121 SER   A CB  1 
ATOM   939  O OG  . SER   A 1 121 ? -24.19646 -28.54137 -13.63349 1.000 46.71898 ?  121 SER   A OG  1 
ATOM   940  N N   . PRO   A 1 122 ? -22.79727 -24.42190 -14.96757 1.000 28.14069 ?  122 PRO   A N   1 
ATOM   941  C CA  . PRO   A 1 122 ? -22.69150 -22.96931 -14.80217 1.000 27.62284 ?  122 PRO   A CA  1 
ATOM   942  C C   . PRO   A 1 122 ? -23.68842 -22.43815 -13.78372 1.000 27.42666 ?  122 PRO   A C   1 
ATOM   943  O O   . PRO   A 1 122 ? -24.87652 -22.76839 -13.81523 1.000 30.82509 ?  122 PRO   A O   1 
ATOM   944  C CB  . PRO   A 1 122 ? -22.98043 -22.45027 -16.21304 1.000 31.02608 ?  122 PRO   A CB  1 
ATOM   945  C CG  . PRO   A 1 122 ? -22.40577 -23.52339 -17.08160 1.000 31.16049 ?  122 PRO   A CG  1 
ATOM   946  C CD  . PRO   A 1 122 ? -22.85061 -24.80410 -16.38969 1.000 29.99010 ?  122 PRO   A CD  1 
ATOM   947  N N   . SER   A 1 123 ? -23.19604 -21.58275 -12.89064 1.000 26.20362 ?  123 SER   A N   1 
ATOM   948  C CA  . SER   A 1 123 ? -24.00137 -21.00983 -11.82289 1.000 25.58721 ?  123 SER   A CA  1 
ATOM   949  C C   . SER   A 1 123 ? -24.22027 -19.52016 -11.99481 1.000 26.35405 ?  123 SER   A C   1 
ATOM   950  O O   . SER   A 1 123 ? -25.30545 -19.02094 -11.70042 1.000 28.38993 ?  123 SER   A O   1 
ATOM   951  C CB  . SER   A 1 123 ? -23.32617 -21.25939 -10.46468 1.000 33.50881 ?  123 SER   A CB  1 
ATOM   952  O OG  . SER   A 1 123 ? -24.01265 -20.58115 -9.42924  1.000 39.16717 ?  123 SER   A OG  1 
ATOM   953  N N   . GLY   A 1 124 ? -23.21520 -18.79511 -12.44099 1.000 24.00785 ?  124 GLY   A N   1 
ATOM   954  C CA  . GLY   A 1 124 ? -23.40161 -17.35933 -12.57040 1.000 24.83472 ?  124 GLY   A CA  1 
ATOM   955  C C   . GLY   A 1 124 ? -22.31506 -16.76049 -13.42233 1.000 25.33845 ?  124 GLY   A C   1 
ATOM   956  O O   . GLY   A 1 124 ? -21.29131 -17.39413 -13.67277 1.000 23.21771 ?  124 GLY   A O   1 
ATOM   957  N N   . VAL   A 1 125 ? -22.55902 -15.53283 -13.89337 1.000 21.59391 ?  125 VAL   A N   1 
ATOM   958  C CA  . VAL   A 1 125 ? -21.58427 -14.84010 -14.72466 1.000 21.56735 ?  125 VAL   A CA  1 
ATOM   959  C C   . VAL   A 1 125 ? -21.41986 -13.42691 -14.19999 1.000 23.91270 ?  125 VAL   A C   1 
ATOM   960  O O   . VAL   A 1 125 ? -22.39984 -12.77042 -13.81458 1.000 25.42691 ?  125 VAL   A O   1 
ATOM   961  C CB  . VAL   A 1 125 ? -21.97064 -14.87199 -16.22510 1.000 25.64796 ?  125 VAL   A CB  1 
ATOM   962  C CG1 . VAL   A 1 125 ? -23.24703 -14.09489 -16.49507 1.000 28.47209 ?  125 VAL   A CG1 1 
ATOM   963  C CG2 . VAL   A 1 125 ? -20.83954 -14.34991 -17.07969 1.000 24.34703 ?  125 VAL   A CG2 1 
ATOM   964  N N   . TYR   A 1 126 ? -20.17590 -12.97534 -14.14377 1.000 22.67097 ?  126 TYR   A N   1 
ATOM   965  C CA  . TYR   A 1 126 ? -19.93074 -11.61537 -13.67150 1.000 23.35018 ?  126 TYR   A CA  1 
ATOM   966  C C   . TYR   A 1 126 ? -18.64560 -11.08178 -14.27869 1.000 26.38236 ?  126 TYR   A C   1 
ATOM   967  O O   . TYR   A 1 126 ? -17.84724 -11.81526 -14.85553 1.000 25.85536 ?  126 TYR   A O   1 
ATOM   968  C CB  . TYR   A 1 126 ? -19.88513 -11.55428 -12.14111 1.000 24.23491 ?  126 TYR   A CB  1 
ATOM   969  C CG  . TYR   A 1 126 ? -18.84329 -12.44970 -11.51069 1.000 26.47985 ?  126 TYR   A CG  1 
ATOM   970  C CD1 . TYR   A 1 126 ? -19.16780 -13.72133 -11.09382 1.000 27.81231 ?  126 TYR   A CD1 1 
ATOM   971  C CD2 . TYR   A 1 126 ? -17.54734 -11.99339 -11.30389 1.000 27.15179 ?  126 TYR   A CD2 1 
ATOM   972  C CE1 . TYR   A 1 126 ? -18.20525 -14.54664 -10.49386 1.000 29.65167 ?  126 TYR   A CE1 1 
ATOM   973  C CE2 . TYR   A 1 126 ? -16.58626 -12.80204 -10.70553 1.000 29.66734 ?  126 TYR   A CE2 1 
ATOM   974  C CZ  . TYR   A 1 126 ? -16.93140 -14.07874 -10.31534 1.000 29.16781 ?  126 TYR   A CZ  1 
ATOM   975  O OH  . TYR   A 1 126 ? -15.97495 -14.86748 -9.71739  1.000 32.16982 ?  126 TYR   A OH  1 
ATOM   976  N N   . GLN   A 1 127 ? -18.45487 -9.77818  -14.17314 1.000 24.91056 ?  127 GLN   A N   1 
ATOM   977  C CA  . GLN   A 1 127 ? -17.31645 -9.12772  -14.78899 1.000 25.67003 ?  127 GLN   A CA  1 
ATOM   978  C C   . GLN   A 1 127 ? -16.23584 -8.88467  -13.73220 1.000 26.81362 ?  127 GLN   A C   1 
ATOM   979  O O   . GLN   A 1 127 ? -16.54957 -8.56174  -12.58438 1.000 28.94586 ?  127 GLN   A O   1 
ATOM   980  C CB  . GLN   A 1 127 ? -17.76335 -7.80651  -15.43754 1.000 28.33026 ?  127 GLN   A CB  1 
ATOM   981  C CG  . GLN   A 1 127 ? -16.78947 -7.25890  -16.44335 1.000 35.81855 ?  127 GLN   A CG  1 
ATOM   982  C CD  . GLN   A 1 127 ? -16.79225 -7.96124  -17.80193 1.000 36.29234 ?  127 GLN   A CD  1 
ATOM   983  O OE1 . GLN   A 1 127 ? -17.46066 -8.98761  -18.01655 1.000 36.08257 ?  127 GLN   A OE1 1 
ATOM   984  N NE2 . GLN   A 1 127 ? -16.01417 -7.40725  -18.73316 1.000 38.67307 ?  127 GLN   A NE2 1 
ATOM   985  N N   . CYS   A 1 128 ? -14.96709 -9.06599  -14.12539 1.000 26.16648 ?  128 CYS   A N   1 
ATOM   986  C CA  . CYS   A 1 128 ? -13.78678 -8.93533  -13.27333 1.000 27.85470 ?  128 CYS   A CA  1 
ATOM   987  C C   . CYS   A 1 128 ? -12.74683 -8.08935  -13.99502 1.000 29.15981 ?  128 CYS   A C   1 
ATOM   988  O O   . CYS   A 1 128 ? -12.73497 -8.01869  -15.22263 1.000 30.19926 ?  128 CYS   A O   1 
ATOM   989  C CB  . CYS   A 1 128 ? -13.12797 -10.33533 -12.96306 1.000 26.78227 ?  128 CYS   A CB  1 
ATOM   990  S SG  . CYS   A 1 128 ? -13.84604 -11.15535 -11.58337 1.000 43.29573 ?  128 CYS   A SG  1 
ATOM   991  N N   . ALA   A 1 129 ? -11.85133 -7.46876  -13.24089 1.000 28.64420 ?  129 ALA   A N   1 
ATOM   992  C CA  . ALA   A 1 129 ? -10.64411 -6.89959  -13.81808 1.000 26.81165 ?  129 ALA   A CA  1 
ATOM   993  C C   . ALA   A 1 129 ? -9.42888  -7.57069  -13.19399 1.000 25.00728 ?  129 ALA   A C   1 
ATOM   994  O O   . ALA   A 1 129 ? -9.42434  -7.85255  -12.00080 1.000 26.84387 ?  129 ALA   A O   1 
ATOM   995  C CB  . ALA   A 1 129 ? -10.55972 -5.39148  -13.58865 1.000 30.46158 ?  129 ALA   A CB  1 
ATOM   996  N N   . MET   A 1 130 ? -8.40193  -7.82229  -14.00013 1.000 26.50585 ?  130 MET   A N   1 
ATOM   997  C CA  . MET   A 1 130 ? -7.13344  -8.27889  -13.46255 1.000 26.03313 ?  130 MET   A CA  1 
ATOM   998  C C   . MET   A 1 130 ? -6.48773  -7.10573  -12.73534 1.000 24.92310 ?  130 MET   A C   1 
ATOM   999  O O   . MET   A 1 130 ? -6.20353  -6.07790  -13.35853 1.000 27.58603 ?  130 MET   A O   1 
ATOM   1000 C CB  . MET   A 1 130 ? -6.22505  -8.79008  -14.58063 1.000 28.12009 ?  130 MET   A CB  1 
ATOM   1001 C CG  . MET   A 1 130 ? -4.84435  -9.29991  -14.11678 1.000 30.23040 ?  130 MET   A CG  1 
ATOM   1002 S SD  . MET   A 1 130 ? -4.93667  -10.72630 -13.01638 1.000 28.87770 ?  130 MET   A SD  1 
ATOM   1003 C CE  . MET   A 1 130 ? -5.54268  -11.96941 -14.17147 1.000 27.51537 ?  130 MET   A CE  1 
ATOM   1004 N N   . ARG   A 1 131 ? -6.26881  -7.24035  -11.42788 1.000 25.89553 ?  131 ARG   A N   1 
ATOM   1005 C CA  . ARG   A 1 131 ? -5.67495  -6.13717  -10.69931 1.000 27.67931 ?  131 ARG   A CA  1 
ATOM   1006 C C   . ARG   A 1 131 ? -4.18905  -6.01789  -11.03874 1.000 26.60046 ?  131 ARG   A C   1 
ATOM   1007 O O   . ARG   A 1 131 ? -3.57289  -6.95651  -11.56282 1.000 24.58643 ?  131 ARG   A O   1 
ATOM   1008 C CB  . ARG   A 1 131 ? -5.87062  -6.30511  -9.19408  1.000 27.17950 ?  131 ARG   A CB  1 
ATOM   1009 C CG  . ARG   A 1 131 ? -7.34103  -6.39956  -8.72602  1.000 25.63905 ?  131 ARG   A CG  1 
ATOM   1010 C CD  . ARG   A 1 131 ? -8.20104  -5.20645  -9.19233  1.000 27.46679 ?  131 ARG   A CD  1 
ATOM   1011 N NE  . ARG   A 1 131 ? -7.60476  -3.93612  -8.78467  1.000 25.95978 ?  131 ARG   A NE  1 
ATOM   1012 C CZ  . ARG   A 1 131 ? -8.13367  -2.75901  -9.08226  1.000 28.23636 ?  131 ARG   A CZ  1 
ATOM   1013 N NH1 . ARG   A 1 131 ? -9.30036  -2.67243  -9.71438  1.000 24.02403 ?  131 ARG   A NH1 1 
ATOM   1014 N NH2 . ARG   A 1 131 ? -7.46570  -1.64910  -8.76182  1.000 24.12100 ?  131 ARG   A NH2 1 
ATOM   1015 N N   . PRO   A 1 132 ? -3.58726  -4.85688  -10.74464 1.000 25.21868 ?  132 PRO   A N   1 
ATOM   1016 C CA  . PRO   A 1 132 ? -2.14579  -4.70978  -10.96553 1.000 24.88308 ?  132 PRO   A CA  1 
ATOM   1017 C C   . PRO   A 1 132 ? -1.30560  -5.66663  -10.14495 1.000 26.25325 ?  132 PRO   A C   1 
ATOM   1018 O O   . PRO   A 1 132 ? -0.18190  -5.97186  -10.54888 1.000 29.17445 ?  132 PRO   A O   1 
ATOM   1019 C CB  . PRO   A 1 132 ? -1.89067  -3.24063  -10.57546 1.000 27.45086 ?  132 PRO   A CB  1 
ATOM   1020 C CG  . PRO   A 1 132 ? -3.18023  -2.55517  -10.99554 1.000 27.07986 ?  132 PRO   A CG  1 
ATOM   1021 C CD  . PRO   A 1 132 ? -4.24426  -3.54577  -10.52889 1.000 25.99892 ?  132 PRO   A CD  1 
ATOM   1022 N N   . ASN   A 1 133 ? -1.80442  -6.14304  -9.01277  1.000 23.51202 ?  133 ASN   A N   1 
ATOM   1023 C CA  . ASN   A 1 133 ? -1.09320  -7.16964  -8.25536  1.000 25.94753 ?  133 ASN   A CA  1 
ATOM   1024 C C   . ASN   A 1 133 ? -1.47823  -8.59381  -8.69065  1.000 26.83758 ?  133 ASN   A C   1 
ATOM   1025 O O   . ASN   A 1 133 ? -1.19532  -9.54942  -7.96027  1.000 27.56868 ?  133 ASN   A O   1 
ATOM   1026 C CB  . ASN   A 1 133 ? -1.32672  -6.97429  -6.74785  1.000 27.70751 ?  133 ASN   A CB  1 
ATOM   1027 C CG  . ASN   A 1 133 ? -2.75814  -7.26385  -6.30869  1.000 26.72224 ?  133 ASN   A CG  1 
ATOM   1028 O OD1 . ASN   A 1 133 ? -3.61997  -7.63138  -7.11236  1.000 27.24579 ?  133 ASN   A OD1 1 
ATOM   1029 N ND2 . ASN   A 1 133 ? -3.01274  -7.11117  -5.02333  1.000 28.21802 ?  133 ASN   A ND2 1 
ATOM   1030 N N   . PHE   A 1 134 ? -2.14927  -8.74095  -9.83431  1.000 26.99328 ?  134 PHE   A N   1 
ATOM   1031 C CA  . PHE   A 1 134 ? -2.45775  -10.04892 -10.42506 1.000 26.78041 ?  134 PHE   A CA  1 
ATOM   1032 C C   . PHE   A 1 134 ? -3.38497  -10.89528 -9.55899  1.000 28.70242 ?  134 PHE   A C   1 
ATOM   1033 O O   . PHE   A 1 134 ? -3.30857  -12.13510 -9.56019  1.000 27.91162 ?  134 PHE   A O   1 
ATOM   1034 C CB  . PHE   A 1 134 ? -1.17170  -10.81295 -10.74292 1.000 27.77342 ?  134 PHE   A CB  1 
ATOM   1035 C CG  . PHE   A 1 134 ? -0.31459  -10.12176 -11.75369 1.000 28.20778 ?  134 PHE   A CG  1 
ATOM   1036 C CD1 . PHE   A 1 134 ? -0.72962  -10.03573 -13.07530 1.000 31.92650 ?  134 PHE   A CD1 1 
ATOM   1037 C CD2 . PHE   A 1 134 ? 0.88820   -9.53713  -11.38217 1.000 34.17097 ?  134 PHE   A CD2 1 
ATOM   1038 C CE1 . PHE   A 1 134 ? 0.04832   -9.38516  -14.01522 1.000 34.78004 ?  134 PHE   A CE1 1 
ATOM   1039 C CE2 . PHE   A 1 134 ? 1.66897   -8.88540  -12.32107 1.000 33.56980 ?  134 PHE   A CE2 1 
ATOM   1040 C CZ  . PHE   A 1 134 ? 1.23925   -8.80518  -13.63893 1.000 35.13904 ?  134 PHE   A CZ  1 
ATOM   1041 N N   . THR   A 1 135 ? -4.27216  -10.25681 -8.82301  1.000 26.90105 ?  135 THR   A N   1 
ATOM   1042 C CA  . THR   A 1 135 ? -5.41141  -10.93044 -8.23133  1.000 24.31414 ?  135 THR   A CA  1 
ATOM   1043 C C   . THR   A 1 135 ? -6.66351  -10.40718 -8.91190  1.000 26.87453 ?  135 THR   A C   1 
ATOM   1044 O O   . THR   A 1 135 ? -6.62831  -9.37723  -9.59360  1.000 27.87174 ?  135 THR   A O   1 
ATOM   1045 C CB  . THR   A 1 135 ? -5.50821  -10.68709 -6.72251  1.000 26.17889 ?  135 THR   A CB  1 
ATOM   1046 O OG1 . THR   A 1 135 ? -5.72124  -9.28668  -6.47042  1.000 26.70711 ?  135 THR   A OG1 1 
ATOM   1047 C CG2 . THR   A 1 135 ? -4.22205  -11.12668 -6.03368  1.000 27.55780 ?  135 THR   A CG2 1 
ATOM   1048 N N   . ILE   A 1 136 ? -7.75883  -11.14290 -8.76006  1.000 26.62141 ?  136 ILE   A N   1 
ATOM   1049 C CA  . ILE   A 1 136 ? -9.05553  -10.64456 -9.19579  1.000 26.96244 ?  136 ILE   A CA  1 
ATOM   1050 C C   . ILE   A 1 136 ? -9.95447  -10.63310 -7.97250  1.000 29.39483 ?  136 ILE   A C   1 
ATOM   1051 O O   . ILE   A 1 136 ? -9.85610  -11.48817 -7.09293  1.000 26.37248 ?  136 ILE   A O   1 
ATOM   1052 C CB  . ILE   A 1 136 ? -9.69050  -11.46958 -10.35318 1.000 30.17622 ?  136 ILE   A CB  1 
ATOM   1053 C CG1 . ILE   A 1 136 ? -9.97730  -12.91626 -9.92962  1.000 25.27533 ?  136 ILE   A CG1 1 
ATOM   1054 C CG2 . ILE   A 1 136 ? -8.79400  -11.43799 -11.60301 1.000 28.22922 ?  136 ILE   A CG2 1 
ATOM   1055 C CD1 . ILE   A 1 136 ? -10.74897 -13.68953 -11.01577 1.000 23.25273 ?  136 ILE   A CD1 1 
ATOM   1056 N N   . LYS   A 1 137 ? -10.83770 -9.63874  -7.90824  1.000 29.72183 ?  137 LYS   A N   1 
ATOM   1057 C CA  . LYS   A 1 137 ? -11.85368 -9.60340  -6.85929  1.000 30.97783 ?  137 LYS   A CA  1 
ATOM   1058 C C   . LYS   A 1 137 ? -13.07129 -10.37037 -7.35085  1.000 31.46113 ?  137 LYS   A C   1 
ATOM   1059 O O   . LYS   A 1 137 ? -14.02258 -9.80905  -7.89095  1.000 29.74454 ?  137 LYS   A O   1 
ATOM   1060 C CB  . LYS   A 1 137 ? -12.18440 -8.15927  -6.50009  1.000 29.73291 ?  137 LYS   A CB  1 
ATOM   1061 C CG  . LYS   A 1 137 ? -10.96924 -7.38962  -6.07967  1.000 40.36181 ?  137 LYS   A CG  1 
ATOM   1062 C CD  . LYS   A 1 137 ? -11.29877 -5.93141  -5.79701  1.000 40.85459 ?  137 LYS   A CD  1 
ATOM   1063 C CE  . LYS   A 1 137 ? -10.28227 -5.32162  -4.85448  1.000 47.18943 ?  137 LYS   A CE  1 
ATOM   1064 N NZ  . LYS   A 1 137 ? -10.78583 -5.24884  -3.44292  1.000 56.33047 ?  137 LYS   A NZ  1 
ATOM   1065 N N   . GLY   A 1 138 ? -13.02069 -11.69567 -7.18078  1.000 29.61818 ?  138 GLY   A N   1 
ATOM   1066 C CA  . GLY   A 1 138 ? -14.04358 -12.58224 -7.67492  1.000 30.63123 ?  138 GLY   A CA  1 
ATOM   1067 C C   . GLY   A 1 138 ? -15.03549 -12.98007 -6.60535  1.000 31.07306 ?  138 GLY   A C   1 
ATOM   1068 O O   . GLY   A 1 138 ? -15.07640 -12.43306 -5.50360  1.000 30.33550 ?  138 GLY   A O   1 
ATOM   1069 N N   . SER   A 1 139 ? -15.85870 -13.95235 -6.95672  1.000 27.80387 ?  139 SER   A N   1 
ATOM   1070 C CA  . SER   A 1 139 ? -16.82525 -14.54113 -6.04181  1.000 29.55001 ?  139 SER   A CA  1 
ATOM   1071 C C   . SER   A 1 139 ? -16.84148 -16.03086 -6.33997  1.000 31.01064 ?  139 SER   A C   1 
ATOM   1072 O O   . SER   A 1 139 ? -17.36022 -16.44914 -7.37714  1.000 29.95776 ?  139 SER   A O   1 
ATOM   1073 C CB  . SER   A 1 139 ? -18.21301 -13.92646 -6.22280  1.000 32.79562 ?  139 SER   A CB  1 
ATOM   1074 O OG  . SER   A 1 139 ? -19.13021 -14.53097 -5.33920  1.000 34.84574 ?  139 SER   A OG  1 
ATOM   1075 N N   . PHE   A 1 140 ? -16.27343 -16.82550 -5.43434  1.000 27.12197 ?  140 PHE   A N   1 
ATOM   1076 C CA  . PHE   A 1 140 ? -16.00874 -18.23161 -5.69539  1.000 26.88243 ?  140 PHE   A CA  1 
ATOM   1077 C C   . PHE   A 1 140 ? -16.15948 -19.00557 -4.39274  1.000 28.68250 ?  140 PHE   A C   1 
ATOM   1078 O O   . PHE   A 1 140 ? -15.70636 -18.54723 -3.34068  1.000 30.69901 ?  140 PHE   A O   1 
ATOM   1079 C CB  . PHE   A 1 140 ? -14.58706 -18.45343 -6.21588  1.000 27.23458 ?  140 PHE   A CB  1 
ATOM   1080 C CG  . PHE   A 1 140 ? -14.31126 -17.95929 -7.61232  1.000 23.82435 ?  140 PHE   A CG  1 
ATOM   1081 C CD1 . PHE   A 1 140 ? -14.89998 -18.56872 -8.71725  1.000 26.29406 ?  140 PHE   A CD1 1 
ATOM   1082 C CD2 . PHE   A 1 140 ? -13.39594 -16.94064 -7.81991  1.000 25.48416 ?  140 PHE   A CD2 1 
ATOM   1083 C CE1 . PHE   A 1 140 ? -14.57262 -18.14036 -10.00952 1.000 22.99311 ?  140 PHE   A CE1 1 
ATOM   1084 C CE2 . PHE   A 1 140 ? -13.07848 -16.50196 -9.09845  1.000 26.83996 ?  140 PHE   A CE2 1 
ATOM   1085 C CZ  . PHE   A 1 140 ? -13.67471 -17.10035 -10.19102 1.000 24.57522 ?  140 PHE   A CZ  1 
ATOM   1086 N N   . LEU   A 1 141 ? -16.74430 -20.18783 -4.47321  1.000 28.72734 ?  141 LEU   A N   1 
ATOM   1087 C CA  . LEU   A 1 141 ? -16.87720 -21.05860 -3.31351  1.000 31.18257 ?  141 LEU   A CA  1 
ATOM   1088 C C   . LEU   A 1 141 ? -16.12870 -22.36721 -3.56573  1.000 33.51496 ?  141 LEU   A C   1 
ATOM   1089 O O   . LEU   A 1 141 ? -15.53426 -22.58612 -4.62658  1.000 27.76161 ?  141 LEU   A O   1 
ATOM   1090 C CB  . LEU   A 1 141 ? -18.35236 -21.30706 -2.99306  1.000 31.63362 ?  141 LEU   A CB  1 
ATOM   1091 C CG  . LEU   A 1 141 ? -19.22209 -20.06493 -2.79809  1.000 34.67794 ?  141 LEU   A CG  1 
ATOM   1092 C CD1 . LEU   A 1 141 ? -20.68310 -20.48210 -2.78239  1.000 38.15372 ?  141 LEU   A CD1 1 
ATOM   1093 C CD2 . LEU   A 1 141 ? -18.84834 -19.34139 -1.51657  1.000 39.78542 ?  141 LEU   A CD2 1 
ATOM   1094 N N   . ASN   A 1 142 ? -16.13488 -23.23975 -2.55897  1.000 35.80926 ?  142 ASN   A N   1 
ATOM   1095 C CA  . ASN   A 1 142 ? -15.56785 -24.56618 -2.74187  1.000 33.47455 ?  142 ASN   A CA  1 
ATOM   1096 C C   . ASN   A 1 142 ? -16.14697 -25.21898 -3.99532  1.000 30.73279 ?  142 ASN   A C   1 
ATOM   1097 O O   . ASN   A 1 142 ? -17.34797 -25.13632 -4.25589  1.000 27.52696 ?  142 ASN   A O   1 
ATOM   1098 C CB  . ASN   A 1 142 ? -15.85561 -25.41952 -1.50325  1.000 36.87095 ?  142 ASN   A CB  1 
ATOM   1099 C CG  . ASN   A 1 142 ? -15.13453 -26.74948 -1.53968  1.000 39.34319 ?  142 ASN   A CG  1 
ATOM   1100 O OD1 . ASN   A 1 142 ? -13.90030 -26.79164 -1.53590  1.000 42.92578 ?  142 ASN   A OD1 1 
ATOM   1101 N ND2 . ASN   A 1 142 ? -15.89714 -27.84608 -1.56867  1.000 43.33654 ?  142 ASN   A ND2 1 
ATOM   1102 N N   . GLY   A 1 143 ? -15.28377 -25.86261 -4.79638  1.000 28.62829 ?  143 GLY   A N   1 
ATOM   1103 C CA  . GLY   A 1 143 ? -15.75795 -26.53528 -5.99995  1.000 26.35092 ?  143 GLY   A CA  1 
ATOM   1104 C C   . GLY   A 1 143 ? -15.68904 -25.71195 -7.27581  1.000 25.43888 ?  143 GLY   A C   1 
ATOM   1105 O O   . GLY   A 1 143 ? -16.00474 -26.23797 -8.35596  1.000 25.55277 ?  143 GLY   A O   1 
ATOM   1106 N N   . SER   A 1 144 ? -15.26600 -24.46081 -7.18595  1.000 23.54648 ?  144 SER   A N   1 
ATOM   1107 C CA  . SER   A 1 144 ? -15.29598 -23.53605 -8.31563  1.000 22.66902 ?  144 SER   A CA  1 
ATOM   1108 C C   . SER   A 1 144 ? -14.04687 -23.59184 -9.18090  1.000 22.21969 ?  144 SER   A C   1 
ATOM   1109 O O   . SER   A 1 144 ? -14.01496 -22.93663 -10.23167 1.000 22.44220 ?  144 SER   A O   1 
ATOM   1110 C CB  . SER   A 1 144 ? -15.46592 -22.09072 -7.80155  1.000 21.81403 ?  144 SER   A CB  1 
ATOM   1111 O OG  . SER   A 1 144 ? -14.39501 -21.70511 -6.95584  1.000 23.63255 ?  144 SER   A OG  1 
ATOM   1112 N N   . CYS   A 1 145 ? -12.98517 -24.27296 -8.74605  1.000 21.13698 ?  145 CYS   A N   1 
ATOM   1113 C CA  . CYS   A 1 145 ? -11.75965 -24.23524 -9.53417  1.000 23.02668 ?  145 CYS   A CA  1 
ATOM   1114 C C   . CYS   A 1 145 ? -11.98248 -24.81889 -10.92438 1.000 19.54558 ?  145 CYS   A C   1 
ATOM   1115 O O   . CYS   A 1 145 ? -12.82897 -25.69339 -11.13458 1.000 22.11606 ?  145 CYS   A O   1 
ATOM   1116 C CB  . CYS   A 1 145 ? -10.63639 -24.96964 -8.80462  1.000 21.53332 ?  145 CYS   A CB  1 
ATOM   1117 S SG  . CYS   A 1 145 ? -9.98561  -23.93098 -7.50903  1.000 24.17351 ?  145 CYS   A SG  1 
ATOM   1118 N N   . GLY   A 1 146 ? -11.23109 -24.30547 -11.89939 1.000 17.57484 ?  146 GLY   A N   1 
ATOM   1119 C CA  . GLY   A 1 146 ? -11.49609 -24.63505 -13.29065 1.000 20.34337 ?  146 GLY   A CA  1 
ATOM   1120 C C   . GLY   A 1 146 ? -12.52107 -23.74243 -13.96727 1.000 20.24307 ?  146 GLY   A C   1 
ATOM   1121 O O   . GLY   A 1 146 ? -12.68612 -23.82090 -15.19202 1.000 20.10151 ?  146 GLY   A O   1 
ATOM   1122 N N   . SER   A 1 147 ? -13.28337 -22.95108 -13.20576 1.000 22.16315 ?  147 SER   A N   1 
ATOM   1123 C CA  . SER   A 1 147 ? -14.10651 -21.92884 -13.85089 1.000 20.05093 ?  147 SER   A CA  1 
ATOM   1124 C C   . SER   A 1 147 ? -13.19982 -21.00374 -14.64452 1.000 19.37483 ?  147 SER   A C   1 
ATOM   1125 O O   . SER   A 1 147 ? -12.06243 -20.74388 -14.24322 1.000 21.30763 ?  147 SER   A O   1 
ATOM   1126 C CB  . SER   A 1 147 ? -14.88363 -21.11033 -12.81764 1.000 21.46818 ?  147 SER   A CB  1 
ATOM   1127 O OG  . SER   A 1 147 ? -15.76085 -21.91327 -12.04076 1.000 23.43610 ?  147 SER   A OG  1 
ATOM   1128 N N   . VAL   A 1 148 ? -13.71400 -20.46615 -15.76490 1.000 20.72302 ?  148 VAL   A N   1 
ATOM   1129 C CA  . VAL   A 1 148 ? -12.84186 -19.70991 -16.65582 1.000 19.78812 ?  148 VAL   A CA  1 
ATOM   1130 C C   . VAL   A 1 148 ? -13.33187 -18.27986 -16.81292 1.000 23.16298 ?  148 VAL   A C   1 
ATOM   1131 O O   . VAL   A 1 148 ? -14.51603 -17.95947 -16.62945 1.000 22.15982 ?  148 VAL   A O   1 
ATOM   1132 C CB  . VAL   A 1 148 ? -12.67912 -20.36422 -18.04954 1.000 21.41407 ?  148 VAL   A CB  1 
ATOM   1133 C CG1 . VAL   A 1 148 ? -11.99339 -21.74850 -17.92144 1.000 21.79532 ?  148 VAL   A CG1 1 
ATOM   1134 C CG2 . VAL   A 1 148 ? -14.02480 -20.45138 -18.80803 1.000 22.92499 ?  148 VAL   A CG2 1 
ATOM   1135 N N   . GLY   A 1 149 ? -12.37802 -17.43256 -17.20557 1.000 21.06741 ?  149 GLY   A N   1 
ATOM   1136 C CA  . GLY   A 1 149 ? -12.64160 -16.05062 -17.60468 1.000 20.94740 ?  149 GLY   A CA  1 
ATOM   1137 C C   . GLY   A 1 149 ? -12.35882 -15.89576 -19.08582 1.000 20.69025 ?  149 GLY   A C   1 
ATOM   1138 O O   . GLY   A 1 149 ? -11.45478 -16.53506 -19.63287 1.000 22.07925 ?  149 GLY   A O   1 
ATOM   1139 N N   . PHE   A 1 150 ? -13.14885 -15.04091 -19.73935 1.000 20.82257 ?  150 PHE   A N   1 
ATOM   1140 C CA  . PHE   A 1 150 ? -13.10216 -14.94448 -21.18683 1.000 22.76144 ?  150 PHE   A CA  1 
ATOM   1141 C C   . PHE   A 1 150 ? -13.56562 -13.56656 -21.65303 1.000 24.04878 ?  150 PHE   A C   1 
ATOM   1142 O O   . PHE   A 1 150 ? -14.29072 -12.84514 -20.95864 1.000 22.38347 ?  150 PHE   A O   1 
ATOM   1143 C CB  . PHE   A 1 150 ? -13.98108 -16.01614 -21.85190 1.000 20.64178 ?  150 PHE   A CB  1 
ATOM   1144 C CG  . PHE   A 1 150 ? -15.40566 -15.90253 -21.50164 1.000 21.58104 ?  150 PHE   A CG  1 
ATOM   1145 C CD1 . PHE   A 1 150 ? -15.86676 -16.36112 -20.28206 1.000 23.55585 ?  150 PHE   A CD1 1 
ATOM   1146 C CD2 . PHE   A 1 150 ? -16.30407 -15.29411 -22.37271 1.000 24.00786 ?  150 PHE   A CD2 1 
ATOM   1147 C CE1 . PHE   A 1 150 ? -17.20344 -16.23277 -19.92946 1.000 22.86679 ?  150 PHE   A CE1 1 
ATOM   1148 C CE2 . PHE   A 1 150 ? -17.65036 -15.17746 -22.03738 1.000 26.44487 ?  150 PHE   A CE2 1 
ATOM   1149 C CZ  . PHE   A 1 150 ? -18.10216 -15.63932 -20.82007 1.000 25.52812 ?  150 PHE   A CZ  1 
ATOM   1150 N N   . ASN   A 1 151 ? -13.14173 -13.22828 -22.86124 1.000 23.71026 ?  151 ASN   A N   1 
ATOM   1151 C CA  . ASN   A 1 151 ? -13.75936 -12.17123 -23.65704 1.000 25.36960 ?  151 ASN   A CA  1 
ATOM   1152 C C   . ASN   A 1 151 ? -14.30929 -12.76147 -24.95293 1.000 28.84721 ?  151 ASN   A C   1 
ATOM   1153 O O   . ASN   A 1 151 ? -13.92111 -13.85947 -25.36764 1.000 28.14928 ?  151 ASN   A O   1 
ATOM   1154 C CB  . ASN   A 1 151 ? -12.74925 -11.06956 -23.95091 1.000 29.92879 ?  151 ASN   A CB  1 
ATOM   1155 C CG  . ASN   A 1 151 ? -12.53045 -10.16742 -22.76001 1.000 33.31268 ?  151 ASN   A CG  1 
ATOM   1156 O OD1 . ASN   A 1 151 ? -13.30337 -9.24250  -22.52975 1.000 35.26542 ?  151 ASN   A OD1 1 
ATOM   1157 N ND2 . ASN   A 1 151 ? -11.50255 -10.45080 -21.97264 1.000 28.35318 ?  151 ASN   A ND2 1 
ATOM   1158 N N   . ILE   A 1 152 ? -15.23603 -12.05496 -25.59617 1.000 30.36658 ?  152 ILE   A N   1 
ATOM   1159 C CA  . ILE   A 1 152 ? -15.78122 -12.51162 -26.87607 1.000 28.71746 ?  152 ILE   A CA  1 
ATOM   1160 C C   . ILE   A 1 152 ? -15.68479 -11.37351 -27.87292 1.000 36.56023 ?  152 ILE   A C   1 
ATOM   1161 O O   . ILE   A 1 152 ? -16.29988 -10.32165 -27.67089 1.000 37.51020 ?  152 ILE   A O   1 
ATOM   1162 C CB  . ILE   A 1 152 ? -17.23501 -12.99798 -26.78622 1.000 31.08762 ?  152 ILE   A CB  1 
ATOM   1163 C CG1 . ILE   A 1 152 ? -17.38927 -14.12784 -25.76666 1.000 30.27406 ?  152 ILE   A CG1 1 
ATOM   1164 C CG2 . ILE   A 1 152 ? -17.68447 -13.49445 -28.17918 1.000 36.86842 ?  152 ILE   A CG2 1 
ATOM   1165 C CD1 . ILE   A 1 152 ? -18.82387 -14.65890 -25.61589 1.000 30.70517 ?  152 ILE   A CD1 1 
ATOM   1166 N N   . ASP   A 1 153 ? -14.95248 -11.59959 -28.96318 1.000 40.57168 ?  153 ASP   A N   1 
ATOM   1167 C CA  . ASP   A 1 153 ? -14.75642 -10.61084 -30.02010 1.000 42.93722 ?  153 ASP   A CA  1 
ATOM   1168 C C   . ASP   A 1 153 ? -15.32467 -11.16675 -31.31518 1.000 45.93418 ?  153 ASP   A C   1 
ATOM   1169 O O   . ASP   A 1 153 ? -14.86238 -12.20360 -31.80040 1.000 43.72541 ?  153 ASP   A O   1 
ATOM   1170 C CB  . ASP   A 1 153 ? -13.27464 -10.27281 -30.17088 1.000 45.89427 ?  153 ASP   A CB  1 
ATOM   1171 C CG  . ASP   A 1 153 ? -12.69465 -9.66373  -28.91145 1.000 54.66142 ?  153 ASP   A CG  1 
ATOM   1172 O OD1 . ASP   A 1 153 ? -13.10663 -8.52592  -28.57497 1.000 58.81020 ?  153 ASP   A OD1 1 
ATOM   1173 O OD2 . ASP   A 1 153 ? -11.86040 -10.33253 -28.24177 1.000 54.38581 -1 153 ASP   A OD2 1 
ATOM   1174 N N   . TYR   A 1 154 ? -16.32095 -10.47176 -31.86935 1.000 48.88666 ?  154 TYR   A N   1 
ATOM   1175 C CA  . TYR   A 1 154 ? -17.13499 -10.98821 -32.96018 1.000 50.51135 ?  154 TYR   A CA  1 
ATOM   1176 C C   . TYR   A 1 154 ? -17.77596 -12.29449 -32.50891 1.000 54.27996 ?  154 TYR   A C   1 
ATOM   1177 O O   . TYR   A 1 154 ? -18.66922 -12.29958 -31.65272 1.000 56.10169 ?  154 TYR   A O   1 
ATOM   1178 C CB  . TYR   A 1 154 ? -16.29877 -11.17574 -34.22900 1.000 51.51694 ?  154 TYR   A CB  1 
ATOM   1179 N N   . ASP   A 1 155 ? -17.30683 -13.41434 -33.04574 1.000 49.51576 ?  155 ASP   A N   1 
ATOM   1180 C CA  . ASP   A 1 155 ? -17.80136 -14.71712 -32.62134 1.000 50.09609 ?  155 ASP   A CA  1 
ATOM   1181 C C   . ASP   A 1 155 ? -16.70611 -15.58839 -32.02161 1.000 46.33880 ?  155 ASP   A C   1 
ATOM   1182 O O   . ASP   A 1 155 ? -16.92907 -16.78751 -31.80802 1.000 46.08517 ?  155 ASP   A O   1 
ATOM   1183 C CB  . ASP   A 1 155 ? -18.46839 -15.43068 -33.79966 1.000 52.45856 ?  155 ASP   A CB  1 
ATOM   1184 C CG  . ASP   A 1 155 ? -17.67865 -15.28643 -35.09399 1.000 55.45502 ?  155 ASP   A CG  1 
ATOM   1185 O OD1 . ASP   A 1 155 ? -16.47769 -14.93698 -35.03581 1.000 58.06911 ?  155 ASP   A OD1 1 
ATOM   1186 O OD2 . ASP   A 1 155 ? -18.25679 -15.54324 -36.17527 1.000 64.74979 -1 155 ASP   A OD2 1 
ATOM   1187 N N   . CYS   A 1 156 ? -15.53985 -15.01750 -31.73361 1.000 42.60694 ?  156 CYS   A N   1 
ATOM   1188 C CA  . CYS   A 1 156 ? -14.39214 -15.76413 -31.24123 1.000 39.63690 ?  156 CYS   A CA  1 
ATOM   1189 C C   . CYS   A 1 156 ? -14.25781 -15.57454 -29.73350 1.000 36.20812 ?  156 CYS   A C   1 
ATOM   1190 O O   . CYS   A 1 156 ? -14.23620 -14.44009 -29.24060 1.000 33.70833 ?  156 CYS   A O   1 
ATOM   1191 C CB  . CYS   A 1 156 ? -13.11361 -15.30714 -31.94620 1.000 41.67903 ?  156 CYS   A CB  1 
ATOM   1192 S SG  . CYS   A 1 156 ? -11.60451 -16.10407 -31.33975 1.000 43.64178 ?  156 CYS   A SG  1 
ATOM   1193 N N   . VAL   A 1 157 ? -14.14819 -16.67662 -29.00394 1.000 30.77712 ?  157 VAL   A N   1 
ATOM   1194 C CA  . VAL   A 1 157 ? -13.99611 -16.60811 -27.55630 1.000 28.09224 ?  157 VAL   A CA  1 
ATOM   1195 C C   . VAL   A 1 157 ? -12.50897 -16.61245 -27.21492 1.000 27.91462 ?  157 VAL   A C   1 
ATOM   1196 O O   . VAL   A 1 157 ? -11.79000 -17.55641 -27.55684 1.000 29.49461 ?  157 VAL   A O   1 
ATOM   1197 C CB  . VAL   A 1 157 ? -14.72657 -17.76943 -26.86210 1.000 24.98567 ?  157 VAL   A CB  1 
ATOM   1198 C CG1 . VAL   A 1 157 ? -14.48588 -17.67260 -25.34118 1.000 25.42579 ?  157 VAL   A CG1 1 
ATOM   1199 C CG2 . VAL   A 1 157 ? -16.20616 -17.72280 -27.18618 1.000 28.83562 ?  157 VAL   A CG2 1 
ATOM   1200 N N   . SER   A 1 158 ? -12.03448 -15.56009 -26.52432 1.000 26.84737 ?  158 SER   A N   1 
ATOM   1201 C CA  . SER   A 1 158 ? -10.66499 -15.51023 -26.01999 1.000 27.80394 ?  158 SER   A CA  1 
ATOM   1202 C C   . SER   A 1 158 ? -10.66936 -15.90200 -24.55017 1.000 27.12741 ?  158 SER   A C   1 
ATOM   1203 O O   . SER   A 1 158 ? -11.12623 -15.12921 -23.70278 1.000 27.71501 ?  158 SER   A O   1 
ATOM   1204 C CB  . SER   A 1 158 ? -10.06067 -14.11321 -26.19585 1.000 34.06747 ?  158 SER   A CB  1 
ATOM   1205 O OG  . SER   A 1 158 ? -9.80079  -13.88199 -27.57473 1.000 39.69445 ?  158 SER   A OG  1 
ATOM   1206 N N   . PHE   A 1 159 ? -10.16855 -17.09836 -24.24493 1.000 25.83975 ?  159 PHE   A N   1 
ATOM   1207 C CA  . PHE   A 1 159 ? -10.07034 -17.54557 -22.86112 1.000 24.67446 ?  159 PHE   A CA  1 
ATOM   1208 C C   . PHE   A 1 159 ? -8.79546  -16.98868 -22.24779 1.000 24.49987 ?  159 PHE   A C   1 
ATOM   1209 O O   . PHE   A 1 159 ? -7.71562  -17.10829 -22.83366 1.000 26.35723 ?  159 PHE   A O   1 
ATOM   1210 C CB  . PHE   A 1 159 ? -10.05397 -19.08208 -22.78306 1.000 21.68621 ?  159 PHE   A CB  1 
ATOM   1211 C CG  . PHE   A 1 159 ? -11.32268 -19.72674 -23.24471 1.000 24.30839 ?  159 PHE   A CG  1 
ATOM   1212 C CD1 . PHE   A 1 159 ? -12.42494 -19.82675 -22.38814 1.000 20.69436 ?  159 PHE   A CD1 1 
ATOM   1213 C CD2 . PHE   A 1 159 ? -11.42754 -20.24994 -24.53044 1.000 22.91335 ?  159 PHE   A CD2 1 
ATOM   1214 C CE1 . PHE   A 1 159 ? -13.59177 -20.42195 -22.81336 1.000 22.17182 ?  159 PHE   A CE1 1 
ATOM   1215 C CE2 . PHE   A 1 159 ? -12.60426 -20.86059 -24.96006 1.000 23.68171 ?  159 PHE   A CE2 1 
ATOM   1216 C CZ  . PHE   A 1 159 ? -13.68965 -20.93411 -24.09651 1.000 23.42978 ?  159 PHE   A CZ  1 
ATOM   1217 N N   . CYS   A 1 160 ? -8.91109  -16.37055 -21.06877 1.000 23.18690 ?  160 CYS   A N   1 
ATOM   1218 C CA  . CYS   A 1 160 ? -7.76755  -15.72635 -20.45287 1.000 23.88291 ?  160 CYS   A CA  1 
ATOM   1219 C C   . CYS   A 1 160 ? -7.49847  -16.12845 -19.01838 1.000 24.28313 ?  160 CYS   A C   1 
ATOM   1220 O O   . CYS   A 1 160 ? -6.42322  -15.79356 -18.49372 1.000 25.34410 ?  160 CYS   A O   1 
ATOM   1221 C CB  . CYS   A 1 160 ? -7.94460  -14.19500 -20.49573 1.000 25.88337 ?  160 CYS   A CB  1 
ATOM   1222 S SG  . CYS   A 1 160 ? -9.41148  -13.62376 -19.66435 1.000 27.67664 ?  160 CYS   A SG  1 
ATOM   1223 N N   . TYR   A 1 161 ? -8.41479  -16.82953 -18.35568 1.000 21.18219 ?  161 TYR   A N   1 
ATOM   1224 C CA  . TYR   A 1 161 ? -8.26571  -17.07087 -16.93144 1.000 22.29048 ?  161 TYR   A CA  1 
ATOM   1225 C C   . TYR   A 1 161 ? -8.86716  -18.43321 -16.60561 1.000 21.78492 ?  161 TYR   A C   1 
ATOM   1226 O O   . TYR   A 1 161 ? -9.90837  -18.79935 -17.14784 1.000 22.16498 ?  161 TYR   A O   1 
ATOM   1227 C CB  . TYR   A 1 161 ? -8.96335  -15.98110 -16.08694 1.000 22.92379 ?  161 TYR   A CB  1 
ATOM   1228 C CG  . TYR   A 1 161 ? -8.86475  -16.19711 -14.57552 1.000 21.77459 ?  161 TYR   A CG  1 
ATOM   1229 C CD1 . TYR   A 1 161 ? -7.73100  -15.79902 -13.85866 1.000 20.82383 ?  161 TYR   A CD1 1 
ATOM   1230 C CD2 . TYR   A 1 161 ? -9.91343  -16.76784 -13.86952 1.000 20.53847 ?  161 TYR   A CD2 1 
ATOM   1231 C CE1 . TYR   A 1 161 ? -7.65092  -15.97752 -12.46188 1.000 22.12559 ?  161 TYR   A CE1 1 
ATOM   1232 C CE2 . TYR   A 1 161 ? -9.84660  -16.95004 -12.48743 1.000 19.90057 ?  161 TYR   A CE2 1 
ATOM   1233 C CZ  . TYR   A 1 161 ? -8.70928  -16.57225 -11.79323 1.000 20.73566 ?  161 TYR   A CZ  1 
ATOM   1234 O OH  . TYR   A 1 161 ? -8.61212  -16.75622 -10.42121 1.000 22.40321 ?  161 TYR   A OH  1 
ATOM   1235 N N   . MET   A 1 162 ? -8.17857  -19.19570 -15.76040 1.000 21.20785 ?  162 MET   A N   1 
ATOM   1236 C CA  . MET   A 1 162 ? -8.72150  -20.40072 -15.13185 1.000 20.36349 ?  162 MET   A CA  1 
ATOM   1237 C C   . MET   A 1 162 ? -8.48002  -20.33220 -13.62403 1.000 19.47601 ?  162 MET   A C   1 
ATOM   1238 O O   . MET   A 1 162 ? -7.38472  -19.97242 -13.16569 1.000 21.18603 ?  162 MET   A O   1 
ATOM   1239 C CB  . MET   A 1 162 ? -8.11125  -21.69915 -15.69718 1.000 22.82773 ?  162 MET   A CB  1 
ATOM   1240 C CG  . MET   A 1 162 ? -8.74511  -22.92625 -15.01206 1.000 21.45825 ?  162 MET   A CG  1 
ATOM   1241 S SD  . MET   A 1 162 ? -8.33563  -24.47188 -15.89898 1.000 28.08967 ?  162 MET   A SD  1 
ATOM   1242 C CE  . MET   A 1 162 ? -9.55805  -24.43876 -17.19574 1.000 24.24336 ?  162 MET   A CE  1 
ATOM   1243 N N   . HIS   A 1 163 ? -9.51427  -20.61759 -12.84538 1.000 21.13293 ?  163 HIS   A N   1 
ATOM   1244 C CA  . HIS   A 1 163 ? -9.47976  -20.27810 -11.43045 1.000 21.94193 ?  163 HIS   A CA  1 
ATOM   1245 C C   . HIS   A 1 163 ? -8.82526  -21.39249 -10.60666 1.000 20.17210 ?  163 HIS   A C   1 
ATOM   1246 O O   . HIS   A 1 163 ? -9.17207  -22.57192 -10.78433 1.000 21.25810 ?  163 HIS   A O   1 
ATOM   1247 C CB  . HIS   A 1 163 ? -10.88931 -20.02932 -10.90088 1.000 22.23135 ?  163 HIS   A CB  1 
ATOM   1248 C CG  . HIS   A 1 163 ? -10.88939 -19.67306 -9.45537  1.000 21.35881 ?  163 HIS   A CG  1 
ATOM   1249 N ND1 . HIS   A 1 163 ? -10.10053 -18.65786 -8.95837  1.000 21.64049 ?  163 HIS   A ND1 1 
ATOM   1250 C CD2 . HIS   A 1 163 ? -11.51532 -20.22670 -8.39190  1.000 22.79294 ?  163 HIS   A CD2 1 
ATOM   1251 C CE1 . HIS   A 1 163 ? -10.24150 -18.59912 -7.64518  1.000 23.46055 ?  163 HIS   A CE1 1 
ATOM   1252 N NE2 . HIS   A 1 163 ? -11.11151 -19.52361 -7.28084  1.000 23.21826 ?  163 HIS   A NE2 1 
ATOM   1253 N N   . HIS   A 1 164 ? -7.91031  -21.01797 -9.68867  1.000 19.07434 ?  164 HIS   A N   1 
ATOM   1254 C CA  . HIS   A 1 164 ? -7.24248  -22.00785 -8.83014  1.000 22.70992 ?  164 HIS   A CA  1 
ATOM   1255 C C   . HIS   A 1 164 ? -7.33474  -21.75363 -7.32310  1.000 25.13170 ?  164 HIS   A C   1 
ATOM   1256 O O   . HIS   A 1 164 ? -7.21255  -22.70447 -6.53449  1.000 25.29723 ?  164 HIS   A O   1 
ATOM   1257 C CB  . HIS   A 1 164 ? -5.74033  -22.10377 -9.15957  1.000 23.16377 ?  164 HIS   A CB  1 
ATOM   1258 C CG  . HIS   A 1 164 ? -5.42184  -22.64557 -10.51606 1.000 24.74101 ?  164 HIS   A CG  1 
ATOM   1259 N ND1 . HIS   A 1 164 ? -4.68538  -23.79924 -10.70084 1.000 27.37603 ?  164 HIS   A ND1 1 
ATOM   1260 C CD2 . HIS   A 1 164 ? -5.66775  -22.15709 -11.75195 1.000 23.42804 ?  164 HIS   A CD2 1 
ATOM   1261 C CE1 . HIS   A 1 164 ? -4.51029  -24.00781 -11.98957 1.000 22.63275 ?  164 HIS   A CE1 1 
ATOM   1262 N NE2 . HIS   A 1 164 ? -5.11709  -23.03367 -12.65336 1.000 27.52857 ?  164 HIS   A NE2 1 
ATOM   1263 N N   . MET   A 1 165 ? -7.44969  -20.49971 -6.87074  1.000 23.62767 ?  165 MET   A N   1 
ATOM   1264 C CA  . MET   A 1 165 ? -7.10030  -20.25671 -5.47142  1.000 25.38270 ?  165 MET   A CA  1 
ATOM   1265 C C   . MET   A 1 165 ? -7.76557  -19.00640 -4.90591  1.000 29.04488 ?  165 MET   A C   1 
ATOM   1266 O O   . MET   A 1 165 ? -7.94323  -18.00924 -5.61813  1.000 24.53619 ?  165 MET   A O   1 
ATOM   1267 C CB  . MET   A 1 165 ? -5.57139  -20.14632 -5.32184  1.000 29.39853 ?  165 MET   A CB  1 
ATOM   1268 C CG  . MET   A 1 165 ? -5.10586  -19.70819 -3.94276  1.000 30.67902 ?  165 MET   A CG  1 
ATOM   1269 S SD  . MET   A 1 165 ? -3.33063  -19.95839 -3.61493  1.000 35.87703 ?  165 MET   A SD  1 
ATOM   1270 C CE  . MET   A 1 165 ? -2.59930  -19.26645 -5.07884  1.000 32.00889 ?  165 MET   A CE  1 
ATOM   1271 N N   . GLU   A 1 166 ? -8.11465  -19.06477 -3.61543  1.000 26.10148 ?  166 GLU   A N   1 
ATOM   1272 C CA  . GLU   A 1 166 ? -8.55167  -17.89714 -2.85154  1.000 25.96416 ?  166 GLU   A CA  1 
ATOM   1273 C C   . GLU   A 1 166 ? -7.48060  -17.55183 -1.82491  1.000 31.03289 ?  166 GLU   A C   1 
ATOM   1274 O O   . GLU   A 1 166 ? -7.13149  -18.39465 -0.99286  1.000 32.03357 ?  166 GLU   A O   1 
ATOM   1275 C CB  . GLU   A 1 166 ? -9.88308  -18.15807 -2.15306  1.000 30.30430 ?  166 GLU   A CB  1 
ATOM   1276 C CG  . GLU   A 1 166 ? -10.36682 -16.98927 -1.31513  1.000 32.02666 ?  166 GLU   A CG  1 
ATOM   1277 C CD  . GLU   A 1 166 ? -11.82667 -17.11664 -0.90196  1.000 38.54480 ?  166 GLU   A CD  1 
ATOM   1278 O OE1 . GLU   A 1 166 ? -12.71145 -17.20246 -1.77180  1.000 34.70246 ?  166 GLU   A OE1 1 
ATOM   1279 O OE2 . GLU   A 1 166 ? -12.10192 -17.10903 0.31177   1.000 43.16491 -1 166 GLU   A OE2 1 
ATOM   1280 N N   . LEU   A 1 167 ? -6.96392  -16.32265 -1.88763  1.000 29.57800 ?  167 LEU   A N   1 
ATOM   1281 C CA  . LEU   A 1 167 ? -5.92642  -15.87028 -0.96170  1.000 31.02580 ?  167 LEU   A CA  1 
ATOM   1282 C C   . LEU   A 1 167 ? -6.50582  -15.60336 0.42425   1.000 33.64606 ?  167 LEU   A C   1 
ATOM   1283 O O   . LEU   A 1 167 ? -7.71350  -15.41434 0.57783   1.000 33.90995 ?  167 LEU   A O   1 
ATOM   1284 C CB  . LEU   A 1 167 ? -5.26521  -14.60481 -1.50189  1.000 30.43841 ?  167 LEU   A CB  1 
ATOM   1285 C CG  . LEU   A 1 167 ? -4.46504  -14.73870 -2.79757  1.000 30.21232 ?  167 LEU   A CG  1 
ATOM   1286 C CD1 . LEU   A 1 167 ? -3.58810  -13.51596 -2.96292  1.000 33.98159 ?  167 LEU   A CD1 1 
ATOM   1287 C CD2 . LEU   A 1 167 ? -3.60607  -16.00985 -2.81658  1.000 34.31760 ?  167 LEU   A CD2 1 
ATOM   1288 N N   . PRO   A 1 168 ? -5.65371  -15.58653 1.45858   1.000 39.22104 ?  168 PRO   A N   1 
ATOM   1289 C CA  . PRO   A 1 168 ? -6.11768  -15.18808 2.80034   1.000 40.96174 ?  168 PRO   A CA  1 
ATOM   1290 C C   . PRO   A 1 168 ? -6.96647  -13.92951 2.82006   1.000 35.06240 ?  168 PRO   A C   1 
ATOM   1291 O O   . PRO   A 1 168 ? -7.92510  -13.85896 3.59852   1.000 43.08193 ?  168 PRO   A O   1 
ATOM   1292 C CB  . PRO   A 1 168 ? -4.80359  -14.98982 3.56343   1.000 39.58322 ?  168 PRO   A CB  1 
ATOM   1293 C CG  . PRO   A 1 168 ? -3.88428  -15.98675 2.93901   1.000 42.30540 ?  168 PRO   A CG  1 
ATOM   1294 C CD  . PRO   A 1 168 ? -4.25783  -16.05432 1.47339   1.000 36.77402 ?  168 PRO   A CD  1 
ATOM   1295 N N   . THR   A 1 169 ? -6.66643  -12.94050 1.97512   1.000 37.91249 ?  169 THR   A N   1 
ATOM   1296 C CA  . THR   A 1 169 ? -7.41684  -11.69205 1.96601   1.000 34.59030 ?  169 THR   A CA  1 
ATOM   1297 C C   . THR   A 1 169 ? -8.78546  -11.80567 1.30185   1.000 37.41059 ?  169 THR   A C   1 
ATOM   1298 O O   . THR   A 1 169 ? -9.54736  -10.83969 1.32936   1.000 37.52927 ?  169 THR   A O   1 
ATOM   1299 C CB  . THR   A 1 169 ? -6.60300  -10.59599 1.26875   1.000 38.77339 ?  169 THR   A CB  1 
ATOM   1300 O OG1 . THR   A 1 169 ? -6.27714  -11.00965 -0.06006  1.000 36.93300 ?  169 THR   A OG1 1 
ATOM   1301 C CG2 . THR   A 1 169 ? -5.30842  -10.33814 2.01762   1.000 36.65412 ?  169 THR   A CG2 1 
ATOM   1302 N N   . GLY   A 1 170 ? -9.12579  -12.94262 0.71143   1.000 36.76548 ?  170 GLY   A N   1 
ATOM   1303 C CA  . GLY   A 1 170 ? -10.42024 -13.06852 0.07589   1.000 34.25550 ?  170 GLY   A CA  1 
ATOM   1304 C C   . GLY   A 1 170 ? -10.44467 -12.72849 -1.39928  1.000 32.19450 ?  170 GLY   A C   1 
ATOM   1305 O O   . GLY   A 1 170 ? -11.51619 -12.81452 -2.01948  1.000 34.96699 ?  170 GLY   A O   1 
ATOM   1306 N N   . VAL   A 1 171 ? -9.31002  -12.34278 -1.98475  1.000 29.74072 ?  171 VAL   A N   1 
ATOM   1307 C CA  . VAL   A 1 171 ? -9.21899  -12.19093 -3.43621  1.000 28.46005 ?  171 VAL   A CA  1 
ATOM   1308 C C   . VAL   A 1 171 ? -8.75422  -13.50520 -4.05524  1.000 27.22173 ?  171 VAL   A C   1 
ATOM   1309 O O   . VAL   A 1 171 ? -8.42978  -14.46430 -3.34478  1.000 28.14549 ?  171 VAL   A O   1 
ATOM   1310 C CB  . VAL   A 1 171 ? -8.29231  -11.02993 -3.82857  1.000 28.52906 ?  171 VAL   A CB  1 
ATOM   1311 C CG1 . VAL   A 1 171 ? -8.74995  -9.73343  -3.13867  1.000 34.04025 ?  171 VAL   A CG1 1 
ATOM   1312 C CG2 . VAL   A 1 171 ? -6.86663  -11.33677 -3.49507  1.000 30.09692 ?  171 VAL   A CG2 1 
ATOM   1313 N N   . HIS   A 1 172 ? -8.71849  -13.56024 -5.38262  1.000 25.87745 ?  172 HIS   A N   1 
ATOM   1314 C CA  . HIS   A 1 172 ? -8.60662  -14.81657 -6.11251  1.000 20.62315 ?  172 HIS   A CA  1 
ATOM   1315 C C   . HIS   A 1 172 ? -7.42759  -14.80549 -7.06593  1.000 24.91592 ?  172 HIS   A C   1 
ATOM   1316 O O   . HIS   A 1 172 ? -7.03590  -13.76574 -7.58562  1.000 24.95261 ?  172 HIS   A O   1 
ATOM   1317 C CB  . HIS   A 1 172 ? -9.92414  -15.08431 -6.85348  1.000 23.30798 ?  172 HIS   A CB  1 
ATOM   1318 C CG  . HIS   A 1 172 ? -11.06111 -15.23366 -5.90927  1.000 24.75622 ?  172 HIS   A CG  1 
ATOM   1319 N ND1 . HIS   A 1 172 ? -11.98261 -14.23099 -5.68435  1.000 26.30322 ?  172 HIS   A ND1 1 
ATOM   1320 C CD2 . HIS   A 1 172 ? -11.35339 -16.22550 -5.03609  1.000 25.39896 ?  172 HIS   A CD2 1 
ATOM   1321 C CE1 . HIS   A 1 172 ? -12.83649 -14.63151 -4.75923  1.000 27.68040 ?  172 HIS   A CE1 1 
ATOM   1322 N NE2 . HIS   A 1 172 ? -12.47909 -15.83840 -4.35158  1.000 27.88472 ?  172 HIS   A NE2 1 
ATOM   1323 N N   . ALA   A 1 173 ? -6.89150  -16.00145 -7.33183  1.000 22.08064 ?  173 ALA   A N   1 
ATOM   1324 C CA  . ALA   A 1 173 ? -5.70961  -16.15252 -8.15389  1.000 23.00975 ?  173 ALA   A CA  1 
ATOM   1325 C C   . ALA   A 1 173 ? -5.87740  -17.35891 -9.07340  1.000 23.20515 ?  173 ALA   A C   1 
ATOM   1326 O O   . ALA   A 1 173 ? -6.56389  -18.33777 -8.74454  1.000 23.78584 ?  173 ALA   A O   1 
ATOM   1327 C CB  . ALA   A 1 173 ? -4.44972  -16.29961 -7.27770  1.000 24.29239 ?  173 ALA   A CB  1 
ATOM   1328 N N   . GLY   A 1 174 ? -5.28635  -17.25090 -10.25446 1.000 22.18789 ?  174 GLY   A N   1 
ATOM   1329 C CA  . GLY   A 1 174 ? -5.40279  -18.32903 -11.22147 1.000 23.82932 ?  174 GLY   A CA  1 
ATOM   1330 C C   . GLY   A 1 174 ? -4.39341  -18.18814 -12.33394 1.000 24.23437 ?  174 GLY   A C   1 
ATOM   1331 O O   . GLY   A 1 174 ? -3.45838  -17.38627 -12.25500 1.000 25.13264 ?  174 GLY   A O   1 
ATOM   1332 N N   . THR   A 1 175 ? -4.60793  -18.96987 -13.39124 1.000 20.83691 ?  175 THR   A N   1 
ATOM   1333 C CA  . THR   A 1 175 ? -3.64807  -19.10392 -14.48002 1.000 23.06457 ?  175 THR   A CA  1 
ATOM   1334 C C   . THR   A 1 175 ? -4.27135  -18.68314 -15.80602 1.000 22.34288 ?  175 THR   A C   1 
ATOM   1335 O O   . THR   A 1 175 ? -5.48100  -18.47675 -15.91010 1.000 23.23541 ?  175 THR   A O   1 
ATOM   1336 C CB  . THR   A 1 175 ? -3.16813  -20.56139 -14.59205 1.000 24.05333 ?  175 THR   A CB  1 
ATOM   1337 O OG1 . THR   A 1 175 ? -4.27973  -21.37741 -15.02408 1.000 23.74566 ?  175 THR   A OG1 1 
ATOM   1338 C CG2 . THR   A 1 175 ? -2.60788  -21.06292 -13.26255 1.000 26.44296 ?  175 THR   A CG2 1 
ATOM   1339 N N   . ASP   A 1 176 ? -3.44102  -18.54411 -16.84911 1.000 22.35234 ?  176 ASP   A N   1 
ATOM   1340 C CA  . ASP   A 1 176 ? -3.97960  -18.53591 -18.20079 1.000 24.90984 ?  176 ASP   A CA  1 
ATOM   1341 C C   . ASP   A 1 176 ? -4.23380  -19.97851 -18.62554 1.000 22.45440 ?  176 ASP   A C   1 
ATOM   1342 O O   . ASP   A 1 176 ? -4.05586  -20.91740 -17.84319 1.000 26.22624 ?  176 ASP   A O   1 
ATOM   1343 C CB  . ASP   A 1 176 ? -3.04427  -17.80503 -19.17473 1.000 25.74562 ?  176 ASP   A CB  1 
ATOM   1344 C CG  . ASP   A 1 176 ? -1.65091  -18.44172 -19.27171 1.000 32.99719 ?  176 ASP   A CG  1 
ATOM   1345 O OD1 . ASP   A 1 176 ? -1.48281  -19.64070 -18.91833 1.000 28.50411 ?  176 ASP   A OD1 1 
ATOM   1346 O OD2 . ASP   A 1 176 ? -0.70400  -17.72328 -19.70812 1.000 29.16541 -1 176 ASP   A OD2 1 
ATOM   1347 N N   . LEU   A 1 177 ? -4.67444  -20.16540 -19.85481 1.000 25.49719 ?  177 LEU   A N   1 
ATOM   1348 C CA  . LEU   A 1 177 ? -5.06291  -21.51360 -20.25237 1.000 22.71090 ?  177 LEU   A CA  1 
ATOM   1349 C C   . LEU   A 1 177 ? -3.87478  -22.35327 -20.69002 1.000 29.42000 ?  177 LEU   A C   1 
ATOM   1350 O O   . LEU   A 1 177 ? -4.06606  -23.51105 -21.08289 1.000 28.48074 ?  177 LEU   A O   1 
ATOM   1351 C CB  . LEU   A 1 177 ? -6.11590  -21.47163 -21.35931 1.000 24.64002 ?  177 LEU   A CB  1 
ATOM   1352 C CG  . LEU   A 1 177 ? -7.55599  -21.51092 -20.83071 1.000 26.23784 ?  177 LEU   A CG  1 
ATOM   1353 C CD1 . LEU   A 1 177 ? -7.87490  -22.88611 -20.21792 1.000 27.08643 ?  177 LEU   A CD1 1 
ATOM   1354 C CD2 . LEU   A 1 177 ? -7.87069  -20.39723 -19.82997 1.000 25.76453 ?  177 LEU   A CD2 1 
ATOM   1355 N N   . GLU   A 1 178 ? -2.66936  -21.78678 -20.67048 1.000 28.48376 ?  178 GLU   A N   1 
ATOM   1356 C CA  . GLU   A 1 178 ? -1.44323  -22.57085 -20.73605 1.000 32.99165 ?  178 GLU   A CA  1 
ATOM   1357 C C   . GLU   A 1 178 ? -0.91146  -22.92137 -19.34497 1.000 28.58559 ?  178 GLU   A C   1 
ATOM   1358 O O   . GLU   A 1 178 ? 0.16180   -23.52052 -19.22784 1.000 29.20282 ?  178 GLU   A O   1 
ATOM   1359 C CB  . GLU   A 1 178 ? -0.38279  -21.82261 -21.56623 1.000 34.59381 ?  178 GLU   A CB  1 
ATOM   1360 C CG  . GLU   A 1 178 ? -0.83013  -21.45969 -22.97011 1.000 33.87770 ?  178 GLU   A CG  1 
ATOM   1361 C CD  . GLU   A 1 178 ? 0.28060   -20.85094 -23.82700 1.000 45.84619 ?  178 GLU   A CD  1 
ATOM   1362 O OE1 . GLU   A 1 178 ? 0.52373   -21.34476 -24.95081 1.000 43.52444 ?  178 GLU   A OE1 1 
ATOM   1363 O OE2 . GLU   A 1 178 ? 0.91732   -19.88156 -23.37558 1.000 41.09769 -1 178 GLU   A OE2 1 
ATOM   1364 N N   . GLY   A 1 179 ? -1.65826  -22.60588 -18.28425 1.000 25.70200 ?  179 GLY   A N   1 
ATOM   1365 C CA  . GLY   A 1 179 ? -1.30976  -23.05241 -16.96254 1.000 24.36313 ?  179 GLY   A CA  1 
ATOM   1366 C C   . GLY   A 1 179 ? -0.31595  -22.18960 -16.22227 1.000 24.35794 ?  179 GLY   A C   1 
ATOM   1367 O O   . GLY   A 1 179 ? 0.14724   -22.59290 -15.15655 1.000 24.67405 ?  179 GLY   A O   1 
ATOM   1368 N N   . ASN   A 1 180 ? 0.02200   -21.01565 -16.74029 1.000 28.86231 ?  180 ASN   A N   1 
ATOM   1369 C CA  . ASN   A 1 180 ? 0.98479   -20.14238 -16.08072 1.000 27.03091 ?  180 ASN   A CA  1 
ATOM   1370 C C   . ASN   A 1 180 ? 0.24416   -19.16550 -15.17610 1.000 27.61741 ?  180 ASN   A C   1 
ATOM   1371 O O   . ASN   A 1 180 ? -0.59290  -18.39653 -15.66368 1.000 26.34620 ?  180 ASN   A O   1 
ATOM   1372 C CB  . ASN   A 1 180 ? 1.80406   -19.36256 -17.11011 1.000 30.52678 ?  180 ASN   A CB  1 
ATOM   1373 C CG  . ASN   A 1 180 ? 2.72726   -20.25664 -17.93385 1.000 33.09210 ?  180 ASN   A CG  1 
ATOM   1374 O OD1 . ASN   A 1 180 ? 2.68023   -20.25105 -19.16353 1.000 39.41455 ?  180 ASN   A OD1 1 
ATOM   1375 N ND2 . ASN   A 1 180 ? 3.56411   -21.01564 -17.25809 1.000 33.57081 ?  180 ASN   A ND2 1 
ATOM   1376 N N   . PHE   A 1 181 ? 0.54557   -19.19118 -13.87988 1.000 27.04407 ?  181 PHE   A N   1 
ATOM   1377 C CA  . PHE   A 1 181 ? -0.16106  -18.30151 -12.96609 1.000 27.58134 ?  181 PHE   A CA  1 
ATOM   1378 C C   . PHE   A 1 181 ? -0.00378  -16.85720 -13.41036 1.000 28.18603 ?  181 PHE   A C   1 
ATOM   1379 O O   . PHE   A 1 181 ? 1.01342   -16.46364 -13.98844 1.000 30.22031 ?  181 PHE   A O   1 
ATOM   1380 C CB  . PHE   A 1 181 ? 0.34056   -18.42848 -11.52180 1.000 25.81898 ?  181 PHE   A CB  1 
ATOM   1381 C CG  . PHE   A 1 181 ? -0.49934  -19.34967 -10.67050 1.000 26.18374 ?  181 PHE   A CG  1 
ATOM   1382 C CD1 . PHE   A 1 181 ? -1.55474  -18.85827 -9.92212  1.000 24.09650 ?  181 PHE   A CD1 1 
ATOM   1383 C CD2 . PHE   A 1 181 ? -0.26741  -20.71812 -10.67521 1.000 27.85064 ?  181 PHE   A CD2 1 
ATOM   1384 C CE1 . PHE   A 1 181 ? -2.34812  -19.69103 -9.16276  1.000 26.73191 ?  181 PHE   A CE1 1 
ATOM   1385 C CE2 . PHE   A 1 181 ? -1.06919  -21.58176 -9.93273  1.000 27.37552 ?  181 PHE   A CE2 1 
ATOM   1386 C CZ  . PHE   A 1 181 ? -2.10908  -21.07253 -9.15616  1.000 27.21563 ?  181 PHE   A CZ  1 
ATOM   1387 N N   . TYR   A 1 182 ? -1.04449  -16.07294 -13.15912 1.000 25.25800 ?  182 TYR   A N   1 
ATOM   1388 C CA  . TYR   A 1 182 ? -0.88905  -14.62816 -13.08745 1.000 26.02211 ?  182 TYR   A CA  1 
ATOM   1389 C C   . TYR   A 1 182 ? -0.32825  -14.28568 -11.71381 1.000 25.40305 ?  182 TYR   A C   1 
ATOM   1390 O O   . TYR   A 1 182 ? -0.92551  -14.63153 -10.69142 1.000 26.68043 ?  182 TYR   A O   1 
ATOM   1391 C CB  . TYR   A 1 182 ? -2.22941  -13.94094 -13.31476 1.000 25.87225 ?  182 TYR   A CB  1 
ATOM   1392 C CG  . TYR   A 1 182 ? -2.76086  -14.06327 -14.72413 1.000 23.96524 ?  182 TYR   A CG  1 
ATOM   1393 C CD1 . TYR   A 1 182 ? -2.30013  -13.22062 -15.74081 1.000 27.39872 ?  182 TYR   A CD1 1 
ATOM   1394 C CD2 . TYR   A 1 182 ? -3.74820  -14.97909 -15.03931 1.000 23.45702 ?  182 TYR   A CD2 1 
ATOM   1395 C CE1 . TYR   A 1 182 ? -2.80748  -13.29721 -17.03267 1.000 27.20906 ?  182 TYR   A CE1 1 
ATOM   1396 C CE2 . TYR   A 1 182 ? -4.23367  -15.07897 -16.32346 1.000 25.35139 ?  182 TYR   A CE2 1 
ATOM   1397 C CZ  . TYR   A 1 182 ? -3.76287  -14.23367 -17.31647 1.000 25.15760 ?  182 TYR   A CZ  1 
ATOM   1398 O OH  . TYR   A 1 182 ? -4.26952  -14.31536 -18.59085 1.000 23.94279 ?  182 TYR   A OH  1 
ATOM   1399 N N   . GLY   A 1 183 ? 0.81601   -13.62819 -11.67442 1.000 27.97778 ?  183 GLY   A N   1 
ATOM   1400 C CA  . GLY   A 1 183 ? 1.35733   -13.21282 -10.39891 1.000 25.01433 ?  183 GLY   A CA  1 
ATOM   1401 C C   . GLY   A 1 183 ? 2.24339   -14.24940 -9.74098  1.000 33.71162 ?  183 GLY   A C   1 
ATOM   1402 O O   . GLY   A 1 183 ? 2.48888   -15.32989 -10.28062 1.000 31.15867 ?  183 GLY   A O   1 
ATOM   1403 N N   . PRO   A 1 184 ? 2.74417   -13.91930 -8.55834  1.000 32.99355 ?  184 PRO   A N   1 
ATOM   1404 C CA  . PRO   A 1 184 ? 3.71417   -14.77546 -7.84228  1.000 36.18053 ?  184 PRO   A CA  1 
ATOM   1405 C C   . PRO   A 1 184 ? 3.01933   -15.76111 -6.90714  1.000 35.78845 ?  184 PRO   A C   1 
ATOM   1406 O O   . PRO   A 1 184 ? 3.18747   -15.71603 -5.68509  1.000 41.58644 ?  184 PRO   A O   1 
ATOM   1407 C CB  . PRO   A 1 184 ? 4.54012   -13.74352 -7.06910  1.000 39.07834 ?  184 PRO   A CB  1 
ATOM   1408 C CG  . PRO   A 1 184 ? 3.51896   -12.67534 -6.72263  1.000 38.03427 ?  184 PRO   A CG  1 
ATOM   1409 C CD  . PRO   A 1 184 ? 2.53204   -12.62819 -7.87729  1.000 34.46484 ?  184 PRO   A CD  1 
ATOM   1410 N N   . PHE   A 1 185 ? 2.19168   -16.62567 -7.48665  1.000 30.85742 ?  185 PHE   A N   1 
ATOM   1411 C CA  . PHE   A 1 185 ? 1.41362   -17.59874 -6.73768  1.000 29.14953 ?  185 PHE   A CA  1 
ATOM   1412 C C   . PHE   A 1 185 ? 1.76840   -18.99415 -7.21599  1.000 27.47735 ?  185 PHE   A C   1 
ATOM   1413 O O   . PHE   A 1 185 ? 2.25270   -19.17064 -8.33476  1.000 29.76046 ?  185 PHE   A O   1 
ATOM   1414 C CB  . PHE   A 1 185 ? -0.09307  -17.32749 -6.89871  1.000 27.52246 ?  185 PHE   A CB  1 
ATOM   1415 C CG  . PHE   A 1 185 ? -0.46407  -15.93523 -6.51679  1.000 29.43193 ?  185 PHE   A CG  1 
ATOM   1416 C CD1 . PHE   A 1 185 ? -0.29255  -15.51979 -5.21244  1.000 26.20444 ?  185 PHE   A CD1 1 
ATOM   1417 C CD2 . PHE   A 1 185 ? -0.92832  -15.02928 -7.45758  1.000 27.88782 ?  185 PHE   A CD2 1 
ATOM   1418 C CE1 . PHE   A 1 185 ? -0.59582  -14.23389 -4.84353  1.000 29.00327 ?  185 PHE   A CE1 1 
ATOM   1419 C CE2 . PHE   A 1 185 ? -1.21569  -13.74007 -7.08922  1.000 28.59279 ?  185 PHE   A CE2 1 
ATOM   1420 C CZ  . PHE   A 1 185 ? -1.05501  -13.34368 -5.78220  1.000 28.97099 ?  185 PHE   A CZ  1 
ATOM   1421 N N   . VAL   A 1 186 ? 1.54079   -19.97619 -6.34307  1.000 31.41432 ?  186 VAL   A N   1 
ATOM   1422 C CA  . VAL   A 1 186 ? 1.76197   -21.37980 -6.66794  1.000 30.52561 ?  186 VAL   A CA  1 
ATOM   1423 C C   . VAL   A 1 186 ? 0.56232   -22.19165 -6.19395  1.000 28.29673 ?  186 VAL   A C   1 
ATOM   1424 O O   . VAL   A 1 186 ? -0.09829  -21.84568 -5.20477  1.000 29.95960 ?  186 VAL   A O   1 
ATOM   1425 C CB  . VAL   A 1 186 ? 3.07519   -21.91156 -6.02997  1.000 30.32897 ?  186 VAL   A CB  1 
ATOM   1426 C CG1 . VAL   A 1 186 ? 4.29175   -21.23471 -6.66160  1.000 29.55433 ?  186 VAL   A CG1 1 
ATOM   1427 C CG2 . VAL   A 1 186 ? 3.03663   -21.69609 -4.54789  1.000 33.94112 ?  186 VAL   A CG2 1 
ATOM   1428 N N   . ASP   A 1 187 ? 0.27751   -23.29735 -6.90479  1.000 29.61688 ?  187 ASP   A N   1 
ATOM   1429 C CA  . ASP   A 1 187 ? -0.87721  -24.12963 -6.55840  1.000 28.66322 ?  187 ASP   A CA  1 
ATOM   1430 C C   . ASP   A 1 187 ? -0.48689  -25.11441 -5.45306  1.000 32.29413 ?  187 ASP   A C   1 
ATOM   1431 O O   . ASP   A 1 187 ? -0.34190  -26.32050 -5.65715  1.000 30.73101 ?  187 ASP   A O   1 
ATOM   1432 C CB  . ASP   A 1 187 ? -1.46314  -24.83565 -7.78433  1.000 27.28093 ?  187 ASP   A CB  1 
ATOM   1433 C CG  . ASP   A 1 187 ? -0.41777  -25.50488 -8.69023  1.000 28.36849 ?  187 ASP   A CG  1 
ATOM   1434 O OD1 . ASP   A 1 187 ? 0.79776   -25.33528 -8.49676  1.000 32.69980 ?  187 ASP   A OD1 1 
ATOM   1435 O OD2 . ASP   A 1 187 ? -0.83166  -26.23629 -9.62300  1.000 26.92516 -1 187 ASP   A OD2 1 
ATOM   1436 N N   . ARG   A 1 188 ? -0.33061  -24.56288 -4.25276  1.000 31.84568 ?  188 ARG   A N   1 
ATOM   1437 C CA  . ARG   A 1 188 ? -0.01744  -25.31117 -3.04065  1.000 34.73723 ?  188 ARG   A CA  1 
ATOM   1438 C C   . ARG   A 1 188 ? -0.90931  -24.79724 -1.92288  1.000 34.90787 ?  188 ARG   A C   1 
ATOM   1439 O O   . ARG   A 1 188 ? -1.26361  -23.61542 -1.89871  1.000 34.02884 ?  188 ARG   A O   1 
ATOM   1440 C CB  . ARG   A 1 188 ? 1.47338   -25.14475 -2.65360  1.000 36.94373 ?  188 ARG   A CB  1 
ATOM   1441 C CG  . ARG   A 1 188 ? 1.89336   -25.82394 -1.36284  1.000 43.95797 ?  188 ARG   A CG  1 
ATOM   1442 C CD  . ARG   A 1 188 ? 3.31722   -25.39951 -0.96009  1.000 42.99441 ?  188 ARG   A CD  1 
ATOM   1443 N NE  . ARG   A 1 188 ? 4.12446   -25.06701 -2.13048  1.000 50.40906 ?  188 ARG   A NE  1 
ATOM   1444 C CZ  . ARG   A 1 188 ? 5.34186   -24.53896 -2.09145  1.000 52.06554 ?  188 ARG   A CZ  1 
ATOM   1445 N NH1 . ARG   A 1 188 ? 5.94390   -24.27026 -0.94382  1.000 52.31549 ?  188 ARG   A NH1 1 
ATOM   1446 N NH2 . ARG   A 1 188 ? 5.96730   -24.26767 -3.23619  1.000 49.51742 ?  188 ARG   A NH2 1 
ATOM   1447 N N   . GLN   A 1 189 ? -1.30355  -25.68566 -1.00816  1.000 30.52033 ?  189 GLN   A N   1 
ATOM   1448 C CA  . GLN   A 1 189 ? -2.20113  -25.29174 0.07499   1.000 33.86402 ?  189 GLN   A CA  1 
ATOM   1449 C C   . GLN   A 1 189 ? -1.38321  -24.58942 1.16297   1.000 40.20151 ?  189 GLN   A C   1 
ATOM   1450 O O   . GLN   A 1 189 ? -1.11199  -25.12275 2.24151   1.000 39.70965 ?  189 GLN   A O   1 
ATOM   1451 C CB  . GLN   A 1 189 ? -2.97543  -26.49812 0.59465   1.000 37.12825 ?  189 GLN   A CB  1 
ATOM   1452 C CG  . GLN   A 1 189 ? -4.10759  -26.19501 1.56796   1.000 39.45690 ?  189 GLN   A CG  1 
ATOM   1453 C CD  . GLN   A 1 189 ? -5.29483  -25.45800 0.94683   1.000 41.15193 ?  189 GLN   A CD  1 
ATOM   1454 O OE1 . GLN   A 1 189 ? -5.24906  -25.01100 -0.20134  1.000 37.79422 ?  189 GLN   A OE1 1 
ATOM   1455 N NE2 . GLN   A 1 189 ? -6.36104  -25.31336 1.72561   1.000 46.40929 ?  189 GLN   A NE2 1 
ATOM   1456 N N   . THR   A 1 190 ? -0.99692  -23.35020 0.84912   1.000 39.75310 ?  190 THR   A N   1 
ATOM   1457 C CA  . THR   A 1 190 ? -0.15527  -22.52101 1.70063   1.000 36.54077 ?  190 THR   A CA  1 
ATOM   1458 C C   . THR   A 1 190 ? -0.59362  -21.06187 1.57805   1.000 40.25949 ?  190 THR   A C   1 
ATOM   1459 O O   . THR   A 1 190 ? -1.14091  -20.63944 0.55293   1.000 39.91912 ?  190 THR   A O   1 
ATOM   1460 C CB  . THR   A 1 190 ? 1.31644   -22.70479 1.31042   1.000 41.01846 ?  190 THR   A CB  1 
ATOM   1461 O OG1 . THR   A 1 190 ? 2.16840   -22.31968 2.39174   1.000 53.21758 ?  190 THR   A OG1 1 
ATOM   1462 C CG2 . THR   A 1 190 ? 1.64915   -21.89481 0.07367   1.000 37.53054 ?  190 THR   A CG2 1 
ATOM   1463 N N   . ALA   A 1 191 ? -0.37180  -20.29694 2.64610   1.000 42.30593 ?  191 ALA   A N   1 
ATOM   1464 C CA  . ALA   A 1 191 ? -0.80374  -18.90332 2.67214   1.000 44.29179 ?  191 ALA   A CA  1 
ATOM   1465 C C   . ALA   A 1 191 ? 0.14462   -18.03905 1.85113   1.000 40.27596 ?  191 ALA   A C   1 
ATOM   1466 O O   . ALA   A 1 191 ? 1.35036   -18.01338 2.10128   1.000 38.59957 ?  191 ALA   A O   1 
ATOM   1467 C CB  . ALA   A 1 191 ? -0.87299  -18.40071 4.11177   1.000 43.27336 ?  191 ALA   A CB  1 
ATOM   1468 N N   . GLN   A 1 192 ? -0.39781  -17.33166 0.85974   1.000 36.29250 ?  192 GLN   A N   1 
ATOM   1469 C CA  . GLN   A 1 192 ? 0.40922   -16.53342 -0.04509  1.000 31.53398 ?  192 GLN   A CA  1 
ATOM   1470 C C   . GLN   A 1 192 ? -0.15566  -15.12255 -0.09651  1.000 35.16778 ?  192 GLN   A C   1 
ATOM   1471 O O   . GLN   A 1 192 ? -1.37285  -14.93432 -0.06624  1.000 37.88672 ?  192 GLN   A O   1 
ATOM   1472 C CB  . GLN   A 1 192 ? 0.43767   -17.16608 -1.44717  1.000 32.01180 ?  192 GLN   A CB  1 
ATOM   1473 C CG  . GLN   A 1 192 ? 0.96416   -18.59261 -1.41670  1.000 32.73474 ?  192 GLN   A CG  1 
ATOM   1474 C CD  . GLN   A 1 192 ? 0.69832   -19.34352 -2.68822  1.000 28.98502 ?  192 GLN   A CD  1 
ATOM   1475 O OE1 . GLN   A 1 192 ? 1.03819   -18.88185 -3.77184  1.000 33.10044 ?  192 GLN   A OE1 1 
ATOM   1476 N NE2 . GLN   A 1 192 ? 0.07949   -20.51400 -2.56534  1.000 32.48863 ?  192 GLN   A NE2 1 
ATOM   1477 N N   . ALA   A 1 193 ? 0.72245   -14.13377 -0.15606  1.000 35.39864 ?  193 ALA   A N   1 
ATOM   1478 C CA  . ALA   A 1 193 ? 0.30574   -12.73814 -0.13482  1.000 40.32028 ?  193 ALA   A CA  1 
ATOM   1479 C C   . ALA   A 1 193 ? 0.52128   -12.10551 -1.50184  1.000 34.14508 ?  193 ALA   A C   1 
ATOM   1480 O O   . ALA   A 1 193 ? 1.48851   -12.42066 -2.20007  1.000 34.70357 ?  193 ALA   A O   1 
ATOM   1481 C CB  . ALA   A 1 193 ? 1.07210   -11.95197 0.93427   1.000 44.79536 ?  193 ALA   A CB  1 
ATOM   1482 N N   . ALA   A 1 194 ? -0.37723  -11.21053 -1.89007  1.000 36.68111 ?  194 ALA   A N   1 
ATOM   1483 C CA  . ALA   A 1 194 ? -0.15100  -10.45910 -3.11290  1.000 32.98403 ?  194 ALA   A CA  1 
ATOM   1484 C C   . ALA   A 1 194 ? 0.57008   -9.14235  -2.80118  1.000 34.99869 ?  194 ALA   A C   1 
ATOM   1485 O O   . ALA   A 1 194 ? 0.61193   -8.68742  -1.66191  1.000 38.27750 ?  194 ALA   A O   1 
ATOM   1486 C CB  . ALA   A 1 194 ? -1.47577  -10.18411 -3.83384  1.000 33.06489 ?  194 ALA   A CB  1 
ATOM   1487 N N   . GLY   A 1 195 ? 1.18011   -8.55504  -3.82533  1.000 35.14142 ?  195 GLY   A N   1 
ATOM   1488 C CA  . GLY   A 1 195 ? 1.69600   -7.20379  -3.68175  1.000 39.13066 ?  195 GLY   A CA  1 
ATOM   1489 C C   . GLY   A 1 195 ? 0.60132   -6.20990  -3.33065  1.000 39.98403 ?  195 GLY   A C   1 
ATOM   1490 O O   . GLY   A 1 195 ? -0.59002  -6.45423  -3.50958  1.000 33.99819 ?  195 GLY   A O   1 
ATOM   1491 N N   . THR   A 1 196 ? 1.00767   -5.06726  -2.78401  1.000 40.44646 ?  196 THR   A N   1 
ATOM   1492 C CA  . THR   A 1 196 ? 0.02999   -4.01481  -2.53897  1.000 39.20186 ?  196 THR   A CA  1 
ATOM   1493 C C   . THR   A 1 196 ? -0.60546  -3.63072  -3.86262  1.000 33.19881 ?  196 THR   A C   1 
ATOM   1494 O O   . THR   A 1 196 ? 0.08779   -3.47586  -4.87041  1.000 39.82068 ?  196 THR   A O   1 
ATOM   1495 C CB  . THR   A 1 196 ? 0.69220   -2.79617  -1.91366  1.000 40.25371 ?  196 THR   A CB  1 
ATOM   1496 O OG1 . THR   A 1 196 ? 1.72976   -2.34864  -2.79251  1.000 43.71378 ?  196 THR   A OG1 1 
ATOM   1497 C CG2 . THR   A 1 196 ? 1.28666   -3.15011  -0.55259  1.000 38.28920 ?  196 THR   A CG2 1 
ATOM   1498 N N   . ASP   A 1 197 ? -1.91700  -3.47952  -3.86782  1.000 31.38569 ?  197 ASP   A N   1 
ATOM   1499 C CA  . ASP   A 1 197 ? -2.54537  -3.19743  -5.14466  1.000 34.07639 ?  197 ASP   A CA  1 
ATOM   1500 C C   . ASP   A 1 197 ? -2.48275  -1.70188  -5.44260  1.000 35.64674 ?  197 ASP   A C   1 
ATOM   1501 O O   . ASP   A 1 197 ? -2.21144  -0.87378  -4.56701  1.000 31.43570 ?  197 ASP   A O   1 
ATOM   1502 C CB  . ASP   A 1 197 ? -3.98417  -3.69034  -5.15682  1.000 30.53280 ?  197 ASP   A CB  1 
ATOM   1503 C CG  . ASP   A 1 197 ? -4.52604  -3.84199  -6.55775  1.000 32.18511 ?  197 ASP   A CG  1 
ATOM   1504 O OD1 . ASP   A 1 197 ? -3.73049  -3.97976  -7.51373  1.000 31.57565 ?  197 ASP   A OD1 1 
ATOM   1505 O OD2 . ASP   A 1 197 ? -5.74513  -3.80723  -6.69917  1.000 29.95491 ?  197 ASP   A OD2 1 
ATOM   1506 N N   . THR   A 1 198 ? -2.74753  -1.35857  -6.70279  1.000 30.38990 ?  198 THR   A N   1 
ATOM   1507 C CA  . THR   A 1 198 ? -2.74134  0.02476   -7.15125  1.000 24.94781 ?  198 THR   A CA  1 
ATOM   1508 C C   . THR   A 1 198 ? -3.97526  0.26301   -8.00449  1.000 27.41375 ?  198 THR   A C   1 
ATOM   1509 O O   . THR   A 1 198 ? -4.67411  -0.67149  -8.40039  1.000 24.41939 ?  198 THR   A O   1 
ATOM   1510 C CB  . THR   A 1 198 ? -1.47217  0.35991   -7.94309  1.000 27.87000 ?  198 THR   A CB  1 
ATOM   1511 O OG1 . THR   A 1 198 ? -1.28352  -0.59177  -8.99443  1.000 29.67709 ?  198 THR   A OG1 1 
ATOM   1512 C CG2 . THR   A 1 198 ? -0.24136  0.32001   -7.03734  1.000 30.65006 ?  198 THR   A CG2 1 
ATOM   1513 N N   . THR   A 1 199 ? -4.23895  1.52542   -8.29694  1.000 24.08642 ?  199 THR   A N   1 
ATOM   1514 C CA  . THR   A 1 199 ? -5.38393  1.88521   -9.12921  1.000 24.46823 ?  199 THR   A CA  1 
ATOM   1515 C C   . THR   A 1 199 ? -5.00842  1.81420   -10.60192 1.000 25.07377 ?  199 THR   A C   1 
ATOM   1516 O O   . THR   A 1 199 ? -3.91623  2.23747   -10.99353 1.000 24.61400 ?  199 THR   A O   1 
ATOM   1517 C CB  . THR   A 1 199 ? -5.87141  3.29986   -8.78459  1.000 26.43061 ?  199 THR   A CB  1 
ATOM   1518 O OG1 . THR   A 1 199 ? -6.19794  3.36098   -7.39740  1.000 27.14652 ?  199 THR   A OG1 1 
ATOM   1519 C CG2 . THR   A 1 199 ? -7.12897  3.67692   -9.57168  1.000 23.27761 ?  199 THR   A CG2 1 
ATOM   1520 N N   . ILE   A 1 200 ? -5.94632  1.33913   -11.42625 1.000 21.55467 ?  200 ILE   A N   1 
ATOM   1521 C CA  . ILE   A 1 200 ? -5.67775  1.09560   -12.84148 1.000 22.83104 ?  200 ILE   A CA  1 
ATOM   1522 C C   . ILE   A 1 200 ? -5.92323  2.40569   -13.58526 1.000 23.45771 ?  200 ILE   A C   1 
ATOM   1523 O O   . ILE   A 1 200 ? -7.05000  2.69141   -14.00879 1.000 22.64650 ?  200 ILE   A O   1 
ATOM   1524 C CB  . ILE   A 1 200 ? -6.54534  -0.01991  -13.41784 1.000 20.89094 ?  200 ILE   A CB  1 
ATOM   1525 C CG1 . ILE   A 1 200 ? -6.30789  -1.32920  -12.66636 1.000 23.48321 ?  200 ILE   A CG1 1 
ATOM   1526 C CG2 . ILE   A 1 200 ? -6.20067  -0.20180  -14.90328 1.000 22.23867 ?  200 ILE   A CG2 1 
ATOM   1527 C CD1 . ILE   A 1 200 ? -7.45283  -2.30494  -12.76711 1.000 24.74976 ?  200 ILE   A CD1 1 
ATOM   1528 N N   . THR   A 1 201 ? -4.83923  3.14523   -13.82286 1.000 22.95947 ?  201 THR   A N   1 
ATOM   1529 C CA  . THR   A 1 201 ? -4.93249  4.50493   -14.36259 1.000 21.96053 ?  201 THR   A CA  1 
ATOM   1530 C C   . THR   A 1 201 ? -5.60497  4.53919   -15.72786 1.000 20.16590 ?  201 THR   A C   1 
ATOM   1531 O O   . THR   A 1 201 ? -6.42672  5.42713   -15.99380 1.000 22.87574 ?  201 THR   A O   1 
ATOM   1532 C CB  . THR   A 1 201 ? -3.53135  5.08678   -14.45398 1.000 24.90679 ?  201 THR   A CB  1 
ATOM   1533 O OG1 . THR   A 1 201 ? -2.87955  4.91634   -13.18529 1.000 24.84067 ?  201 THR   A OG1 1 
ATOM   1534 C CG2 . THR   A 1 201 ? -3.57739  6.58199   -14.82658 1.000 25.12584 ?  201 THR   A CG2 1 
ATOM   1535 N N   . VAL   A 1 202 ? -5.25054  3.61539   -16.62522 1.000 21.63601 ?  202 VAL   A N   1 
ATOM   1536 C CA  . VAL   A 1 202 ? -5.82848  3.70780   -17.97261 1.000 21.63955 ?  202 VAL   A CA  1 
ATOM   1537 C C   . VAL   A 1 202 ? -7.34491  3.54020   -17.92905 1.000 24.50256 ?  202 VAL   A C   1 
ATOM   1538 O O   . VAL   A 1 202 ? -8.08334  4.16459   -18.72686 1.000 20.63643 ?  202 VAL   A O   1 
ATOM   1539 C CB  . VAL   A 1 202 ? -5.16985  2.69508   -18.93329 1.000 22.10570 ?  202 VAL   A CB  1 
ATOM   1540 C CG1 . VAL   A 1 202 ? -5.44976  1.26501   -18.49308 1.000 25.62273 ?  202 VAL   A CG1 1 
ATOM   1541 C CG2 . VAL   A 1 202 ? -5.66995  2.92893   -20.40189 1.000 22.53424 ?  202 VAL   A CG2 1 
ATOM   1542 N N   . ASN   A 1 203 ? -7.84801  2.74987   -16.98522 1.000 21.72639 ?  203 ASN   A N   1 
ATOM   1543 C CA  . ASN   A 1 203 ? -9.29314  2.59741   -16.84894 1.000 21.75078 ?  203 ASN   A CA  1 
ATOM   1544 C C   . ASN   A 1 203 ? -9.93952  3.82596   -16.22898 1.000 22.86946 ?  203 ASN   A C   1 
ATOM   1545 O O   . ASN   A 1 203 ? -11.05147 4.21144   -16.61941 1.000 23.72646 ?  203 ASN   A O   1 
ATOM   1546 C CB  . ASN   A 1 203 ? -9.61350  1.35716   -16.01882 1.000 22.00464 ?  203 ASN   A CB  1 
ATOM   1547 C CG  . ASN   A 1 203 ? -9.29531  0.09224   -16.74738 1.000 21.89857 ?  203 ASN   A CG  1 
ATOM   1548 O OD1 . ASN   A 1 203 ? -8.85852  0.12414   -17.89499 1.000 23.77683 ?  203 ASN   A OD1 1 
ATOM   1549 N ND2 . ASN   A 1 203 ? -9.48014  -1.04388  -16.08155 1.000 23.35983 ?  203 ASN   A ND2 1 
ATOM   1550 N N   . VAL   A 1 204 ? -9.27279  4.46255   -15.26928 1.000 20.79761 ?  204 VAL   A N   1 
ATOM   1551 C CA  . VAL   A 1 204 ? -9.82459  5.71092   -14.74411 1.000 21.14327 ?  204 VAL   A CA  1 
ATOM   1552 C C   . VAL   A 1 204 ? -9.92781  6.73169   -15.86396 1.000 23.21748 ?  204 VAL   A C   1 
ATOM   1553 O O   . VAL   A 1 204 ? -10.93185 7.45767   -15.98270 1.000 23.49183 ?  204 VAL   A O   1 
ATOM   1554 C CB  . VAL   A 1 204 ? -8.97681  6.23203   -13.56675 1.000 24.45481 ?  204 VAL   A CB  1 
ATOM   1555 C CG1 . VAL   A 1 204 ? -9.47210  7.60382   -13.12031 1.000 23.14618 ?  204 VAL   A CG1 1 
ATOM   1556 C CG2 . VAL   A 1 204 ? -9.03243  5.26799   -12.37138 1.000 24.57535 ?  204 VAL   A CG2 1 
ATOM   1557 N N   . LEU   A 1 205 ? -8.90614  6.79394   -16.72284 1.000 22.21172 ?  205 LEU   A N   1 
ATOM   1558 C CA  . LEU   A 1 205 ? -8.97752  7.72948   -17.84602 1.000 21.22734 ?  205 LEU   A CA  1 
ATOM   1559 C C   . LEU   A 1 205 ? -10.14053 7.38388   -18.77147 1.000 21.78804 ?  205 LEU   A C   1 
ATOM   1560 O O   . LEU   A 1 205 ? -10.84523 8.27666   -19.25630 1.000 22.85847 ?  205 LEU   A O   1 
ATOM   1561 C CB  . LEU   A 1 205 ? -7.65705  7.72774   -18.62056 1.000 18.85687 ?  205 LEU   A CB  1 
ATOM   1562 C CG  . LEU   A 1 205 ? -6.45661  8.30897   -17.85842 1.000 22.33690 ?  205 LEU   A CG  1 
ATOM   1563 C CD1 . LEU   A 1 205 ? -5.20239  7.99784   -18.65894 1.000 21.40544 ?  205 LEU   A CD1 1 
ATOM   1564 C CD2 . LEU   A 1 205 ? -6.63338  9.82420   -17.70475 1.000 23.97429 ?  205 LEU   A CD2 1 
ATOM   1565 N N   . ALA   A 1 206 ? -10.36585 6.09441   -19.00765 1.000 22.17468 ?  206 ALA   A N   1 
ATOM   1566 C CA  . ALA   A 1 206 ? -11.48428 5.69949   -19.87417 1.000 21.89570 ?  206 ALA   A CA  1 
ATOM   1567 C C   . ALA   A 1 206 ? -12.81768 6.15560   -19.29430 1.000 23.41468 ?  206 ALA   A C   1 
ATOM   1568 O O   . ALA   A 1 206 ? -13.72348 6.59691   -20.03108 1.000 23.85694 ?  206 ALA   A O   1 
ATOM   1569 C CB  . ALA   A 1 206 ? -11.45693 4.18456   -20.03180 1.000 21.56564 ?  206 ALA   A CB  1 
ATOM   1570 N N   . TRP   A 1 207 ? -12.95795 6.00716   -17.97979 1.000 24.27654 ?  207 TRP   A N   1 
ATOM   1571 C CA  . TRP   A 1 207 ? -14.12633 6.47167   -17.24408 1.000 27.87570 ?  207 TRP   A CA  1 
ATOM   1572 C C   . TRP   A 1 207 ? -14.30023 7.98726   -17.36358 1.000 27.72552 ?  207 TRP   A C   1 
ATOM   1573 O O   . TRP   A 1 207 ? -15.41742 8.47005   -17.58324 1.000 27.92944 ?  207 TRP   A O   1 
ATOM   1574 C CB  . TRP   A 1 207 ? -13.97390 6.03858   -15.77891 1.000 28.45088 ?  207 TRP   A CB  1 
ATOM   1575 C CG  . TRP   A 1 207 ? -15.08102 6.43052   -14.82614 1.000 31.62692 ?  207 TRP   A CG  1 
ATOM   1576 C CD1 . TRP   A 1 207 ? -15.03741 7.40173   -13.86926 1.000 31.27112 ?  207 TRP   A CD1 1 
ATOM   1577 C CD2 . TRP   A 1 207 ? -16.37887 5.83545   -14.74026 1.000 33.23666 ?  207 TRP   A CD2 1 
ATOM   1578 N NE1 . TRP   A 1 207 ? -16.24288 7.44834   -13.18797 1.000 34.81916 ?  207 TRP   A NE1 1 
ATOM   1579 C CE2 . TRP   A 1 207 ? -17.07824 6.49676   -13.70892 1.000 33.64482 ?  207 TRP   A CE2 1 
ATOM   1580 C CE3 . TRP   A 1 207 ? -17.01717 4.81341   -15.43950 1.000 34.53896 ?  207 TRP   A CE3 1 
ATOM   1581 C CZ2 . TRP   A 1 207 ? -18.38491 6.15819   -13.35673 1.000 40.54027 ?  207 TRP   A CZ2 1 
ATOM   1582 C CZ3 . TRP   A 1 207 ? -18.31516 4.47482   -15.09093 1.000 43.33313 ?  207 TRP   A CZ3 1 
ATOM   1583 C CH2 . TRP   A 1 207 ? -18.98639 5.14878   -14.05640 1.000 42.04983 ?  207 TRP   A CH2 1 
ATOM   1584 N N   . LEU   A 1 208 ? -13.21114 8.75633   -17.23560 1.000 24.72302 ?  208 LEU   A N   1 
ATOM   1585 C CA  . LEU   A 1 208 ? -13.32541 10.21416  -17.43895 1.000 24.43572 ?  208 LEU   A CA  1 
ATOM   1586 C C   . LEU   A 1 208 ? -13.76429 10.54729  -18.86612 1.000 24.23901 ?  208 LEU   A C   1 
ATOM   1587 O O   . LEU   A 1 208 ? -14.57464 11.46289  -19.08031 1.000 26.39505 ?  208 LEU   A O   1 
ATOM   1588 C CB  . LEU   A 1 208 ? -12.00178 10.91232  -17.12783 1.000 25.22108 ?  208 LEU   A CB  1 
ATOM   1589 C CG  . LEU   A 1 208 ? -11.54472 10.78128  -15.68368 1.000 29.96624 ?  208 LEU   A CG  1 
ATOM   1590 C CD1 . LEU   A 1 208 ? -10.21597 11.51144  -15.51812 1.000 27.12407 ?  208 LEU   A CD1 1 
ATOM   1591 C CD2 . LEU   A 1 208 ? -12.62262 11.34241  -14.74379 1.000 28.55990 ?  208 LEU   A CD2 1 
ATOM   1592 N N   . TYR   A 1 209 ? -13.23522 9.82573   -19.86096 1.000 23.59259 ?  209 TYR   A N   1 
ATOM   1593 C CA  . TYR   A 1 209 ? -13.70764 10.04218  -21.23296 1.000 22.84625 ?  209 TYR   A CA  1 
ATOM   1594 C C   . TYR   A 1 209 ? -15.19774 9.74592   -21.34911 1.000 25.11046 ?  209 TYR   A C   1 
ATOM   1595 O O   . TYR   A 1 209 ? -15.94348 10.50686  -21.98005 1.000 26.82407 ?  209 TYR   A O   1 
ATOM   1596 C CB  . TYR   A 1 209 ? -12.92074 9.18797   -22.22965 1.000 22.84373 ?  209 TYR   A CB  1 
ATOM   1597 C CG  . TYR   A 1 209 ? -11.62205 9.82824   -22.67845 1.000 25.05656 ?  209 TYR   A CG  1 
ATOM   1598 C CD1 . TYR   A 1 209 ? -11.61861 10.92595  -23.52908 1.000 25.40629 ?  209 TYR   A CD1 1 
ATOM   1599 C CD2 . TYR   A 1 209 ? -10.39458 9.32538   -22.25031 1.000 24.16044 ?  209 TYR   A CD2 1 
ATOM   1600 C CE1 . TYR   A 1 209 ? -10.43579 11.49733  -23.95302 1.000 24.35174 ?  209 TYR   A CE1 1 
ATOM   1601 C CE2 . TYR   A 1 209 ? -9.21003  9.88673   -22.65893 1.000 26.85279 ?  209 TYR   A CE2 1 
ATOM   1602 C CZ  . TYR   A 1 209 ? -9.22068  10.98282  -23.48964 1.000 26.66002 ?  209 TYR   A CZ  1 
ATOM   1603 O OH  . TYR   A 1 209 ? -8.01616  11.50788  -23.88563 1.000 25.58891 ?  209 TYR   A OH  1 
ATOM   1604 N N   . ALA   A 1 210 ? -15.64622 8.64380   -20.73720 1.000 25.40436 ?  210 ALA   A N   1 
ATOM   1605 C CA  . ALA   A 1 210 ? -17.06452 8.30886   -20.71534 1.000 29.13023 ?  210 ALA   A CA  1 
ATOM   1606 C C   . ALA   A 1 210 ? -17.88853 9.43076   -20.10191 1.000 27.61295 ?  210 ALA   A C   1 
ATOM   1607 O O   . ALA   A 1 210 ? -18.97645 9.75011   -20.59769 1.000 29.94229 ?  210 ALA   A O   1 
ATOM   1608 C CB  . ALA   A 1 210 ? -17.29642 7.01233   -19.93354 1.000 29.05968 ?  210 ALA   A CB  1 
ATOM   1609 N N   . ALA   A 1 211 ? -17.40925 10.00280  -18.99886 1.000 25.90168 ?  211 ALA   A N   1 
ATOM   1610 C CA  . ALA   A 1 211 ? -18.09701 11.14077  -18.39392 1.000 29.04993 ?  211 ALA   A CA  1 
ATOM   1611 C C   . ALA   A 1 211 ? -18.22911 12.29033  -19.39119 1.000 27.71867 ?  211 ALA   A C   1 
ATOM   1612 O O   . ALA   A 1 211 ? -19.31075 12.87065  -19.54684 1.000 30.71196 ?  211 ALA   A O   1 
ATOM   1613 C CB  . ALA   A 1 211 ? -17.34969 11.60830  -17.14521 1.000 28.74694 ?  211 ALA   A CB  1 
ATOM   1614 N N   . VAL   A 1 212 ? -17.12663 12.64189  -20.06477 1.000 27.17124 ?  212 VAL   A N   1 
ATOM   1615 C CA  . VAL   A 1 212 ? -17.16617 13.73056  -21.05329 1.000 25.67374 ?  212 VAL   A CA  1 
ATOM   1616 C C   . VAL   A 1 212 ? -18.18515 13.43490  -22.14498 1.000 27.29960 ?  212 VAL   A C   1 
ATOM   1617 O O   . VAL   A 1 212 ? -18.94458 14.32657  -22.56990 1.000 26.69207 ?  212 VAL   A O   1 
ATOM   1618 C CB  . VAL   A 1 212 ? -15.76838 13.98398  -21.65589 1.000 26.29006 ?  212 VAL   A CB  1 
ATOM   1619 C CG1 . VAL   A 1 212 ? -15.85936 15.04046  -22.75397 1.000 25.56897 ?  212 VAL   A CG1 1 
ATOM   1620 C CG2 . VAL   A 1 212 ? -14.79266 14.43340  -20.55382 1.000 27.37039 ?  212 VAL   A CG2 1 
ATOM   1621 N N   . ILE   A 1 213 ? -18.20850 12.19493  -22.63697 1.000 25.61927 ?  213 ILE   A N   1 
ATOM   1622 C CA  . ILE   A 1 213 ? -19.12727 11.84473  -23.72641 1.000 26.48200 ?  213 ILE   A CA  1 
ATOM   1623 C C   . ILE   A 1 213 ? -20.56702 12.10339  -23.31495 1.000 30.03174 ?  213 ILE   A C   1 
ATOM   1624 O O   . ILE   A 1 213 ? -21.41784 12.46113  -24.15224 1.000 26.98448 ?  213 ILE   A O   1 
ATOM   1625 C CB  . ILE   A 1 213 ? -18.90513 10.37249  -24.14193 1.000 25.26984 ?  213 ILE   A CB  1 
ATOM   1626 C CG1 . ILE   A 1 213 ? -17.53289 10.22463  -24.81929 1.000 27.41300 ?  213 ILE   A CG1 1 
ATOM   1627 C CG2 . ILE   A 1 213 ? -20.04591 9.84172   -25.02698 1.000 28.11829 ?  213 ILE   A CG2 1 
ATOM   1628 C CD1 . ILE   A 1 213 ? -17.04703 8.76037   -24.96787 1.000 29.40887 ?  213 ILE   A CD1 1 
ATOM   1629 N N   . ASN   A 1 214 ? -20.85411 11.96091  -22.02126 1.000 29.66520 ?  214 ASN   A N   1 
ATOM   1630 C CA  . ASN   A 1 214 ? -22.17352 12.14415  -21.43917 1.000 30.80990 ?  214 ASN   A CA  1 
ATOM   1631 C C   . ASN   A 1 214 ? -22.43216 13.55865  -20.95414 1.000 34.04645 ?  214 ASN   A C   1 
ATOM   1632 O O   . ASN   A 1 214 ? -23.44689 13.78599  -20.28291 1.000 37.02634 ?  214 ASN   A O   1 
ATOM   1633 C CB  . ASN   A 1 214 ? -22.36459 11.15939  -20.28291 1.000 35.47546 ?  214 ASN   A CB  1 
ATOM   1634 C CG  . ASN   A 1 214 ? -22.69827 9.78015   -20.77229 1.000 43.26510 ?  214 ASN   A CG  1 
ATOM   1635 O OD1 . ASN   A 1 214 ? -21.82260 9.03475   -21.23287 1.000 45.21729 ?  214 ASN   A OD1 1 
ATOM   1636 N ND2 . ASN   A 1 214 ? -23.98087 9.42981   -20.70403 1.000 50.04939 ?  214 ASN   A ND2 1 
ATOM   1637 N N   . GLY   A 1 215 ? -21.54364 14.50745  -21.25908 1.000 30.02699 ?  215 GLY   A N   1 
ATOM   1638 C CA  . GLY   A 1 215 ? -21.75031 15.90988  -20.93670 1.000 28.68116 ?  215 GLY   A CA  1 
ATOM   1639 C C   . GLY   A 1 215 ? -21.27578 16.32885  -19.56437 1.000 32.07918 ?  215 GLY   A C   1 
ATOM   1640 O O   . GLY   A 1 215 ? -21.54622 17.46218  -19.14770 1.000 35.26140 ?  215 GLY   A O   1 
ATOM   1641 N N   . ASP   A 1 216 ? -20.56424 15.46099  -18.86014 1.000 30.17536 ?  216 ASP   A N   1 
ATOM   1642 C CA  . ASP   A 1 216 ? -20.08981 15.72203  -17.50480 1.000 34.86549 ?  216 ASP   A CA  1 
ATOM   1643 C C   . ASP   A 1 216 ? -18.59865 16.03091  -17.61140 1.000 35.05090 ?  216 ASP   A C   1 
ATOM   1644 O O   . ASP   A 1 216 ? -17.76956 15.11592  -17.66666 1.000 34.51604 ?  216 ASP   A O   1 
ATOM   1645 C CB  . ASP   A 1 216 ? -20.36839 14.50456  -16.62830 1.000 33.87545 ?  216 ASP   A CB  1 
ATOM   1646 C CG  . ASP   A 1 216 ? -20.41840 14.83312  -15.14826 1.000 41.30780 ?  216 ASP   A CG  1 
ATOM   1647 O OD1 . ASP   A 1 216 ? -20.24306 16.01065  -14.79068 1.000 41.32563 ?  216 ASP   A OD1 1 
ATOM   1648 O OD2 . ASP   A 1 216 ? -20.64826 13.89837  -14.34495 1.000 44.35978 -1 216 ASP   A OD2 1 
ATOM   1649 N N   . ARG   A 1 217 ? -18.24860 17.32618  -17.65879 1.000 34.80837 ?  217 ARG   A N   1 
ATOM   1650 C CA  . ARG   A 1 217 ? -16.87777 17.67583  -18.01613 1.000 33.44256 ?  217 ARG   A CA  1 
ATOM   1651 C C   . ARG   A 1 217 ? -16.29742 18.81980  -17.18395 1.000 34.82307 ?  217 ARG   A C   1 
ATOM   1652 O O   . ARG   A 1 217 ? -15.36669 19.49458  -17.64198 1.000 35.00462 ?  217 ARG   A O   1 
ATOM   1653 C CB  . ARG   A 1 217 ? -16.80107 18.01642  -19.50484 1.000 35.48284 ?  217 ARG   A CB  1 
ATOM   1654 C CG  . ARG   A 1 217 ? -17.93922 18.85806  -19.97335 1.000 35.56175 ?  217 ARG   A CG  1 
ATOM   1655 C CD  . ARG   A 1 217 ? -17.76048 19.29537  -21.42044 1.000 31.65765 ?  217 ARG   A CD  1 
ATOM   1656 N NE  . ARG   A 1 217 ? -18.63329 20.42806  -21.68606 1.000 34.05454 ?  217 ARG   A NE  1 
ATOM   1657 C CZ  . ARG   A 1 217 ? -19.85887 20.32507  -22.18400 1.000 31.20110 ?  217 ARG   A CZ  1 
ATOM   1658 N NH1 . ARG   A 1 217 ? -20.35297 19.16217  -22.56562 1.000 28.55303 ?  217 ARG   A NH1 1 
ATOM   1659 N NH2 . ARG   A 1 217 ? -20.60640 21.42293  -22.30368 1.000 32.84532 ?  217 ARG   A NH2 1 
ATOM   1660 N N   . TRP   A 1 218 ? -16.78623 19.02200  -15.96037 1.000 34.16051 ?  218 TRP   A N   1 
ATOM   1661 C CA  . TRP   A 1 218 ? -16.30016 20.12372  -15.13260 1.000 39.75597 ?  218 TRP   A CA  1 
ATOM   1662 C C   . TRP   A 1 218 ? -14.81759 19.98621  -14.79774 1.000 41.17007 ?  218 TRP   A C   1 
ATOM   1663 O O   . TRP   A 1 218 ? -14.14443 20.99194  -14.53515 1.000 36.71540 ?  218 TRP   A O   1 
ATOM   1664 C CB  . TRP   A 1 218 ? -17.12555 20.19920  -13.84673 1.000 42.18053 ?  218 TRP   A CB  1 
ATOM   1665 C CG  . TRP   A 1 218 ? -17.03940 18.96782  -12.99043 1.000 41.62721 ?  218 TRP   A CG  1 
ATOM   1666 C CD1 . TRP   A 1 218 ? -17.91564 17.91931  -12.96452 1.000 39.50253 ?  218 TRP   A CD1 1 
ATOM   1667 C CD2 . TRP   A 1 218 ? -16.02508 18.66517  -12.01916 1.000 41.21231 ?  218 TRP   A CD2 1 
ATOM   1668 N NE1 . TRP   A 1 218 ? -17.50280 16.97740  -12.04439 1.000 42.60991 ?  218 TRP   A NE1 1 
ATOM   1669 C CE2 . TRP   A 1 218 ? -16.34701 17.41349  -11.45300 1.000 39.82596 ?  218 TRP   A CE2 1 
ATOM   1670 C CE3 . TRP   A 1 218 ? -14.87270 19.32606  -11.58449 1.000 43.16820 ?  218 TRP   A CE3 1 
ATOM   1671 C CZ2 . TRP   A 1 218 ? -15.55869 16.81134  -10.47450 1.000 46.59659 ?  218 TRP   A CZ2 1 
ATOM   1672 C CZ3 . TRP   A 1 218 ? -14.08932 18.72482  -10.61342 1.000 45.15992 ?  218 TRP   A CZ3 1 
ATOM   1673 C CH2 . TRP   A 1 218 ? -14.44002 17.48021  -10.06847 1.000 44.75231 ?  218 TRP   A CH2 1 
ATOM   1674 N N   . PHE   A 1 219 ? -14.29376 18.75671  -14.80283 1.000 37.08263 ?  219 PHE   A N   1 
ATOM   1675 C CA  . PHE   A 1 219 ? -12.93856 18.46107  -14.35219 1.000 36.58241 ?  219 PHE   A CA  1 
ATOM   1676 C C   . PHE   A 1 219 ? -11.88082 18.69108  -15.41936 1.000 36.93592 ?  219 PHE   A C   1 
ATOM   1677 O O   . PHE   A 1 219 ? -10.68879 18.53156  -15.12458 1.000 36.98747 ?  219 PHE   A O   1 
ATOM   1678 C CB  . PHE   A 1 219 ? -12.86117 17.00887  -13.86636 1.000 33.98345 ?  219 PHE   A CB  1 
ATOM   1679 C CG  . PHE   A 1 219 ? -13.45466 16.03601  -14.83854 1.000 32.53660 ?  219 PHE   A CG  1 
ATOM   1680 C CD1 . PHE   A 1 219 ? -12.69175 15.53412  -15.88201 1.000 32.53559 ?  219 PHE   A CD1 1 
ATOM   1681 C CD2 . PHE   A 1 219 ? -14.77940 15.64452  -14.72563 1.000 30.16809 ?  219 PHE   A CD2 1 
ATOM   1682 C CE1 . PHE   A 1 219 ? -13.24188 14.65807  -16.80006 1.000 29.30295 ?  219 PHE   A CE1 1 
ATOM   1683 C CE2 . PHE   A 1 219 ? -15.33699 14.76889  -15.64872 1.000 30.77567 ?  219 PHE   A CE2 1 
ATOM   1684 C CZ  . PHE   A 1 219 ? -14.56585 14.28392  -16.68121 1.000 29.36359 ?  219 PHE   A CZ  1 
ATOM   1685 N N   . LEU   A 1 220 ? -12.28116 19.01652  -16.64651 1.000 34.96336 ?  220 LEU   A N   1 
ATOM   1686 C CA  . LEU   A 1 220 ? -11.32838 19.31145  -17.70479 1.000 34.09215 ?  220 LEU   A CA  1 
ATOM   1687 C C   . LEU   A 1 220 ? -10.63861 20.63184  -17.40691 1.000 44.58863 ?  220 LEU   A C   1 
ATOM   1688 O O   . LEU   A 1 220 ? -11.29029 21.68316  -17.38482 1.000 43.80754 ?  220 LEU   A O   1 
ATOM   1689 C CB  . LEU   A 1 220 ? -12.03590 19.38416  -19.05331 1.000 34.24596 ?  220 LEU   A CB  1 
ATOM   1690 C CG  . LEU   A 1 220 ? -12.71421 18.12476  -19.58653 1.000 34.77044 ?  220 LEU   A CG  1 
ATOM   1691 C CD1 . LEU   A 1 220 ? -13.40741 18.42603  -20.90946 1.000 31.91801 ?  220 LEU   A CD1 1 
ATOM   1692 C CD2 . LEU   A 1 220 ? -11.68797 16.98749  -19.73353 1.000 33.93635 ?  220 LEU   A CD2 1 
ATOM   1693 N N   . ASN   A 1 221 ? -9.33037  20.58785  -17.17506 1.000 38.54974 ?  221 ASN   A N   1 
ATOM   1694 C CA  . ASN   A 1 221 ? -8.57492  21.81298  -16.95723 1.000 43.38915 ?  221 ASN   A CA  1 
ATOM   1695 C C   . ASN   A 1 221 ? -7.89626  22.22758  -18.25865 1.000 41.85089 ?  221 ASN   A C   1 
ATOM   1696 O O   . ASN   A 1 221 ? -7.98451  21.54073  -19.27387 1.000 42.02057 ?  221 ASN   A O   1 
ATOM   1697 C CB  . ASN   A 1 221 ? -7.57576  21.64720  -15.80196 1.000 45.20755 ?  221 ASN   A CB  1 
ATOM   1698 C CG  . ASN   A 1 221 ? -6.42040  20.69028  -16.11749 1.000 41.03352 ?  221 ASN   A CG  1 
ATOM   1699 O OD1 . ASN   A 1 221 ? -6.12784  20.37371  -17.27024 1.000 42.10050 ?  221 ASN   A OD1 1 
ATOM   1700 N ND2 . ASN   A 1 221 ? -5.73578  20.25656  -15.06767 1.000 45.75932 ?  221 ASN   A ND2 1 
ATOM   1701 N N   . ARG   A 1 222 ? -7.19174  23.36018  -18.22787 1.000 47.31789 ?  222 ARG   A N   1 
ATOM   1702 C CA  . ARG   A 1 222 ? -6.61151  23.93104  -19.43702 1.000 44.29175 ?  222 ARG   A CA  1 
ATOM   1703 C C   . ARG   A 1 222 ? -5.15453  23.53682  -19.64229 1.000 48.23643 ?  222 ARG   A C   1 
ATOM   1704 O O   . ARG   A 1 222 ? -4.44275  24.20972  -20.39602 1.000 45.75035 ?  222 ARG   A O   1 
ATOM   1705 C CB  . ARG   A 1 222 ? -6.73954  25.45705  -19.41555 1.000 54.50974 ?  222 ARG   A CB  1 
ATOM   1706 N N   . PHE   A 1 223 ? -4.70133  22.45551  -19.01129 1.000 43.40280 ?  223 PHE   A N   1 
ATOM   1707 C CA  . PHE   A 1 223 ? -3.28637  22.11350  -18.96875 1.000 44.05752 ?  223 PHE   A CA  1 
ATOM   1708 C C   . PHE   A 1 223 ? -3.00819  20.80716  -19.70324 1.000 41.98145 ?  223 PHE   A C   1 
ATOM   1709 O O   . PHE   A 1 223 ? -3.91125  20.03668  -20.04295 1.000 38.62983 ?  223 PHE   A O   1 
ATOM   1710 C CB  . PHE   A 1 223 ? -2.80287  22.01275  -17.52033 1.000 44.30220 ?  223 PHE   A CB  1 
ATOM   1711 C CG  . PHE   A 1 223 ? -2.65994  23.34498  -16.84083 1.000 52.92998 ?  223 PHE   A CG  1 
ATOM   1712 C CD1 . PHE   A 1 223 ? -2.09619  24.41930  -17.51234 1.000 54.02136 ?  223 PHE   A CD1 1 
ATOM   1713 C CD2 . PHE   A 1 223 ? -3.08878  23.52476  -15.53409 1.000 55.17694 ?  223 PHE   A CD2 1 
ATOM   1714 C CE1 . PHE   A 1 223 ? -1.95783  25.65107  -16.89044 1.000 55.85419 ?  223 PHE   A CE1 1 
ATOM   1715 C CE2 . PHE   A 1 223 ? -2.95305  24.75458  -14.90516 1.000 56.41553 ?  223 PHE   A CE2 1 
ATOM   1716 C CZ  . PHE   A 1 223 ? -2.38744  25.81624  -15.58383 1.000 58.03093 ?  223 PHE   A CZ  1 
ATOM   1717 N N   . THR   A 1 224 ? -1.72824  20.56505  -19.95694 1.000 38.79428 ?  224 THR   A N   1 
ATOM   1718 C CA  . THR   A 1 224 ? -1.28744  19.27092  -20.44232 1.000 35.03347 ?  224 THR   A CA  1 
ATOM   1719 C C   . THR   A 1 224 ? -0.07848  18.84756  -19.61471 1.000 33.17582 ?  224 THR   A C   1 
ATOM   1720 O O   . THR   A 1 224 ? 0.36335   19.55271  -18.70213 1.000 35.62564 ?  224 THR   A O   1 
ATOM   1721 C CB  . THR   A 1 224 ? -0.97841  19.30356  -21.94530 1.000 32.82246 ?  224 THR   A CB  1 
ATOM   1722 O OG1 . THR   A 1 224 ? -1.02495  17.97374  -22.48301 1.000 34.81829 ?  224 THR   A OG1 1 
ATOM   1723 C CG2 . THR   A 1 224 ? 0.38221   19.91774  -22.22770 1.000 37.11634 ?  224 THR   A CG2 1 
ATOM   1724 N N   . THR   A 1 225 ? 0.43337   17.66892  -19.91528 1.000 35.23558 ?  225 THR   A N   1 
ATOM   1725 C CA  . THR   A 1 225 ? 1.56862   17.13718  -19.18088 1.000 31.97267 ?  225 THR   A CA  1 
ATOM   1726 C C   . THR   A 1 225 ? 2.32209   16.21968  -20.12384 1.000 34.04506 ?  225 THR   A C   1 
ATOM   1727 O O   . THR   A 1 225 ? 1.82862   15.85524  -21.18991 1.000 34.41653 ?  225 THR   A O   1 
ATOM   1728 C CB  . THR   A 1 225 ? 1.12808   16.39891  -17.90948 1.000 35.53447 ?  225 THR   A CB  1 
ATOM   1729 O OG1 . THR   A 1 225 ? 2.27837   15.84988  -17.25195 1.000 34.62700 ?  225 THR   A OG1 1 
ATOM   1730 C CG2 . THR   A 1 225 ? 0.19185   15.25682  -18.24273 1.000 32.96787 ?  225 THR   A CG2 1 
ATOM   1731 N N   . THR   A 1 226 ? 3.54635   15.87572  -19.74106 1.000 32.28510 ?  226 THR   A N   1 
ATOM   1732 C CA  . THR   A 1 226 ? 4.22864   14.79941  -20.43637 1.000 34.44335 ?  226 THR   A CA  1 
ATOM   1733 C C   . THR   A 1 226 ? 3.81769   13.47279  -19.81341 1.000 28.50010 ?  226 THR   A C   1 
ATOM   1734 O O   . THR   A 1 226 ? 3.37922   13.40835  -18.66142 1.000 30.82064 ?  226 THR   A O   1 
ATOM   1735 C CB  . THR   A 1 226 ? 5.74762   14.95553  -20.34494 1.000 32.92955 ?  226 THR   A CB  1 
ATOM   1736 O OG1 . THR   A 1 226 ? 6.12604   14.84247  -18.97300 1.000 32.15784 ?  226 THR   A OG1 1 
ATOM   1737 C CG2 . THR   A 1 226 ? 6.18849   16.32018  -20.86195 1.000 33.14572 ?  226 THR   A CG2 1 
ATOM   1738 N N   . LEU   A 1 227 ? 3.97779   12.40360  -20.58837 1.000 28.91717 ?  227 LEU   A N   1 
ATOM   1739 C CA  . LEU   A 1 227 ? 3.67844   11.07653  -20.06180 1.000 26.07726 ?  227 LEU   A CA  1 
ATOM   1740 C C   . LEU   A 1 227 ? 4.58949   10.75098  -18.88572 1.000 28.98331 ?  227 LEU   A C   1 
ATOM   1741 O O   . LEU   A 1 227 ? 4.14246   10.21135  -17.86707 1.000 28.16595 ?  227 LEU   A O   1 
ATOM   1742 C CB  . LEU   A 1 227 ? 3.83240   10.04091  -21.16951 1.000 29.63448 ?  227 LEU   A CB  1 
ATOM   1743 C CG  . LEU   A 1 227 ? 3.21953   8.66041   -20.92147 1.000 32.93887 ?  227 LEU   A CG  1 
ATOM   1744 C CD1 . LEU   A 1 227 ? 1.72044   8.80059   -20.65382 1.000 34.01046 ?  227 LEU   A CD1 1 
ATOM   1745 C CD2 . LEU   A 1 227 ? 3.45976   7.77054   -22.13105 1.000 32.26362 ?  227 LEU   A CD2 1 
ATOM   1746 N N   . ASN   A 1 228 ? 5.86928   11.07996  -19.00143 1.000 27.15684 ?  228 ASN   A N   1 
ATOM   1747 C CA  . ASN   A 1 228 ? 6.80671   10.76952  -17.91654 1.000 29.10157 ?  228 ASN   A CA  1 
ATOM   1748 C C   . ASN   A 1 228 ? 6.48055   11.55346  -16.64008 1.000 28.61573 ?  228 ASN   A C   1 
ATOM   1749 O O   . ASN   A 1 228 ? 6.46817   10.99943  -15.52920 1.000 26.43315 ?  228 ASN   A O   1 
ATOM   1750 C CB  . ASN   A 1 228 ? 8.22645   11.04769  -18.39780 1.000 28.64078 ?  228 ASN   A CB  1 
ATOM   1751 C CG  . ASN   A 1 228 ? 9.27067   10.74511  -17.33680 1.000 28.57600 ?  228 ASN   A CG  1 
ATOM   1752 O OD1 . ASN   A 1 228 ? 9.95329   11.64699  -16.85164 1.000 31.63061 ?  228 ASN   A OD1 1 
ATOM   1753 N ND2 . ASN   A 1 228 ? 9.39746   9.47261   -16.97695 1.000 29.04760 ?  228 ASN   A ND2 1 
ATOM   1754 N N   . ASP   A 1 229 ? 6.21738   12.85469  -16.76917 1.000 27.99660 ?  229 ASP   A N   1 
ATOM   1755 C CA  . ASP   A 1 229 ? 5.83324   13.60545  -15.57975 1.000 30.13652 ?  229 ASP   A CA  1 
ATOM   1756 C C   . ASP   A 1 229 ? 4.57202   13.01811  -14.95813 1.000 29.47901 ?  229 ASP   A C   1 
ATOM   1757 O O   . ASP   A 1 229 ? 4.48879   12.85349  -13.72984 1.000 28.66061 ?  229 ASP   A O   1 
ATOM   1758 C CB  . ASP   A 1 229 ? 5.62773   15.08347  -15.92660 1.000 33.86722 ?  229 ASP   A CB  1 
ATOM   1759 C CG  . ASP   A 1 229 ? 5.07935   15.88833  -14.75722 1.000 41.01969 ?  229 ASP   A CG  1 
ATOM   1760 O OD1 . ASP   A 1 229 ? 3.83952   16.01034  -14.62905 1.000 45.78399 ?  229 ASP   A OD1 1 
ATOM   1761 O OD2 . ASP   A 1 229 ? 5.88908   16.38802  -13.94759 1.000 54.08362 -1 229 ASP   A OD2 1 
ATOM   1762 N N   . PHE   A 1 230 ? 3.57982   12.67830  -15.79556 1.000 25.92603 ?  230 PHE   A N   1 
ATOM   1763 C CA  . PHE   A 1 230 ? 2.35899   12.11411  -15.24673 1.000 27.32563 ?  230 PHE   A CA  1 
ATOM   1764 C C   . PHE   A 1 230 ? 2.64346   10.80380  -14.50814 1.000 26.62406 ?  230 PHE   A C   1 
ATOM   1765 O O   . PHE   A 1 230 ? 2.11379   10.56957  -13.42432 1.000 25.29307 ?  230 PHE   A O   1 
ATOM   1766 C CB  . PHE   A 1 230 ? 1.31545   11.89744  -16.34421 1.000 25.51342 ?  230 PHE   A CB  1 
ATOM   1767 C CG  . PHE   A 1 230 ? 0.09547   11.18184  -15.84432 1.000 29.74060 ?  230 PHE   A CG  1 
ATOM   1768 C CD1 . PHE   A 1 230 ? -0.89253  11.86525  -15.15511 1.000 28.49397 ?  230 PHE   A CD1 1 
ATOM   1769 C CD2 . PHE   A 1 230 ? -0.02630  9.80795   -15.99683 1.000 32.25889 ?  230 PHE   A CD2 1 
ATOM   1770 C CE1 . PHE   A 1 230 ? -1.99901  11.19632  -14.65270 1.000 27.44859 ?  230 PHE   A CE1 1 
ATOM   1771 C CE2 . PHE   A 1 230 ? -1.11647  9.13642   -15.49747 1.000 32.63211 ?  230 PHE   A CE2 1 
ATOM   1772 C CZ  . PHE   A 1 230 ? -2.11167  9.82930   -14.82911 1.000 32.77389 ?  230 PHE   A CZ  1 
ATOM   1773 N N   . ASN   A 1 231 ? 3.43563   9.91807   -15.10764 1.000 25.26502 ?  231 ASN   A N   1 
ATOM   1774 C CA  . ASN   A 1 231 ? 3.69650   8.62658   -14.47429 1.000 22.45787 ?  231 ASN   A CA  1 
ATOM   1775 C C   . ASN   A 1 231 ? 4.35858   8.80251   -13.11787 1.000 24.95331 ?  231 ASN   A C   1 
ATOM   1776 O O   . ASN   A 1 231 ? 3.96749   8.16072   -12.13374 1.000 26.16566 ?  231 ASN   A O   1 
ATOM   1777 C CB  . ASN   A 1 231 ? 4.57437   7.77190   -15.38315 1.000 24.57972 ?  231 ASN   A CB  1 
ATOM   1778 C CG  . ASN   A 1 231 ? 3.76077   7.12755   -16.48757 1.000 26.44834 ?  231 ASN   A CG  1 
ATOM   1779 O OD1 . ASN   A 1 231 ? 2.54110   7.25246   -16.48186 1.000 26.60389 ?  231 ASN   A OD1 1 
ATOM   1780 N ND2 . ASN   A 1 231 ? 4.41597   6.42965   -17.41425 1.000 24.69090 ?  231 ASN   A ND2 1 
ATOM   1781 N N   . LEU   A 1 232 ? 5.33527   9.70141   -13.04570 1.000 26.74250 ?  232 LEU   A N   1 
ATOM   1782 C CA  . LEU   A 1 232 ? 6.01811   9.92058   -11.77437 1.000 26.56385 ?  232 LEU   A CA  1 
ATOM   1783 C C   . LEU   A 1 232 ? 5.07088   10.47764  -10.72180 1.000 29.96514 ?  232 LEU   A C   1 
ATOM   1784 O O   . LEU   A 1 232 ? 5.14822   10.09544  -9.55107  1.000 31.07364 ?  232 LEU   A O   1 
ATOM   1785 C CB  . LEU   A 1 232 ? 7.20396   10.85776  -11.96727 1.000 28.43600 ?  232 LEU   A CB  1 
ATOM   1786 C CG  . LEU   A 1 232 ? 8.30457   10.30076  -12.85928 1.000 32.27415 ?  232 LEU   A CG  1 
ATOM   1787 C CD1 . LEU   A 1 232 ? 9.38150   11.34374  -13.09712 1.000 33.69045 ?  232 LEU   A CD1 1 
ATOM   1788 C CD2 . LEU   A 1 232 ? 8.89239   9.05109   -12.21515 1.000 29.64414 ?  232 LEU   A CD2 1 
ATOM   1789 N N   . VAL   A 1 233 ? 4.16349   11.38146  -11.10882 1.000 28.01256 ?  233 VAL   A N   1 
ATOM   1790 C CA  . VAL   A 1 233 ? 3.19983   11.87023  -10.12253 1.000 28.27789 ?  233 VAL   A CA  1 
ATOM   1791 C C   . VAL   A 1 233 ? 2.21228   10.77555  -9.73547  1.000 27.69744 ?  233 VAL   A C   1 
ATOM   1792 O O   . VAL   A 1 233 ? 1.89457   10.59190  -8.55499  1.000 29.56101 ?  233 VAL   A O   1 
ATOM   1793 C CB  . VAL   A 1 233 ? 2.45972   13.11327  -10.64051 1.000 29.71540 ?  233 VAL   A CB  1 
ATOM   1794 C CG1 . VAL   A 1 233 ? 1.41931   13.54350  -9.60553  1.000 31.96609 ?  233 VAL   A CG1 1 
ATOM   1795 C CG2 . VAL   A 1 233 ? 3.43117   14.23741  -10.91400 1.000 31.97306 ?  233 VAL   A CG2 1 
ATOM   1796 N N   . ALA   A 1 234 ? 1.66827   10.06334  -10.72830 1.000 27.90288 ?  234 ALA   A N   1 
ATOM   1797 C CA  . ALA   A 1 234 ? 0.60902   9.10093   -10.44826 1.000 28.50767 ?  234 ALA   A CA  1 
ATOM   1798 C C   . ALA   A 1 234 ? 1.08629   8.04401   -9.46536  1.000 27.09929 ?  234 ALA   A C   1 
ATOM   1799 O O   . ALA   A 1 234 ? 0.32932   7.62910   -8.57808  1.000 27.30326 ?  234 ALA   A O   1 
ATOM   1800 C CB  . ALA   A 1 234 ? 0.11800   8.45031   -11.74861 1.000 29.12499 ?  234 ALA   A CB  1 
ATOM   1801 N N   . MET   A 1 235 ? 2.35135   7.62873   -9.58181  1.000 27.15931 ?  235 MET   A N   1 
ATOM   1802 C CA  . MET   A 1 235 ? 2.84189   6.58153   -8.68467  1.000 30.01500 ?  235 MET   A CA  1 
ATOM   1803 C C   . MET   A 1 235 ? 2.81308   7.01662   -7.22040  1.000 31.97345 ?  235 MET   A C   1 
ATOM   1804 O O   . MET   A 1 235 ? 2.65045   6.17062   -6.33395  1.000 31.28419 ?  235 MET   A O   1 
ATOM   1805 C CB  . MET   A 1 235 ? 4.24410   6.14918   -9.10605  1.000 29.06382 ?  235 MET   A CB  1 
ATOM   1806 C CG  . MET   A 1 235 ? 4.22818   5.32221   -10.39023 1.000 35.44223 ?  235 MET   A CG  1 
ATOM   1807 S SD  . MET   A 1 235 ? 5.81620   4.65939   -10.90860 1.000 48.46116 ?  235 MET   A SD  1 
ATOM   1808 C CE  . MET   A 1 235 ? 6.83109   6.13240   -10.82912 1.000 38.27728 ?  235 MET   A CE  1 
ATOM   1809 N N   . LYS   A 1 236 ? 2.91330   8.32644   -6.94356  1.000 31.36039 ?  236 LYS   A N   1 
ATOM   1810 C CA  . LYS   A 1 236 ? 2.83982   8.78556   -5.55275  1.000 29.74146 ?  236 LYS   A CA  1 
ATOM   1811 C C   . LYS   A 1 236 ? 1.44120   8.64698   -4.96390  1.000 33.05506 ?  236 LYS   A C   1 
ATOM   1812 O O   . LYS   A 1 236 ? 1.28632   8.67289   -3.73431  1.000 33.95201 ?  236 LYS   A O   1 
ATOM   1813 C CB  . LYS   A 1 236 ? 3.30219   10.23894  -5.45349  1.000 34.46065 ?  236 LYS   A CB  1 
ATOM   1814 C CG  . LYS   A 1 236 ? 4.69974   10.47127  -6.01487  1.000 33.28353 ?  236 LYS   A CG  1 
ATOM   1815 C CD  . LYS   A 1 236 ? 5.12367   11.89449  -5.74781  1.000 42.05524 ?  236 LYS   A CD  1 
ATOM   1816 C CE  . LYS   A 1 236 ? 6.33356   12.28841  -6.58154  1.000 46.41006 ?  236 LYS   A CE  1 
ATOM   1817 N NZ  . LYS   A 1 236 ? 5.99094   13.53810  -7.35060  1.000 47.33524 ?  236 LYS   A NZ  1 
ATOM   1818 N N   . TYR   A 1 237 ? 0.42054   8.49868   -5.80870  1.000 28.04703 ?  237 TYR   A N   1 
ATOM   1819 C CA  . TYR   A 1 237 ? -0.95323  8.30425   -5.37318  1.000 28.30684 ?  237 TYR   A CA  1 
ATOM   1820 C C   . TYR   A 1 237 ? -1.39305  6.85676   -5.47441  1.000 30.56670 ?  237 TYR   A C   1 
ATOM   1821 O O   . TYR   A 1 237 ? -2.58951  6.57949   -5.35113  1.000 32.24189 ?  237 TYR   A O   1 
ATOM   1822 C CB  . TYR   A 1 237 ? -1.90356  9.18184   -6.19929  1.000 26.98046 ?  237 TYR   A CB  1 
ATOM   1823 C CG  . TYR   A 1 237 ? -1.69886  10.63444  -5.85533  1.000 29.79027 ?  237 TYR   A CG  1 
ATOM   1824 C CD1 . TYR   A 1 237 ? -0.71452  11.36954  -6.48247  1.000 29.64863 ?  237 TYR   A CD1 1 
ATOM   1825 C CD2 . TYR   A 1 237 ? -2.46157  11.24451  -4.87485  1.000 33.87115 ?  237 TYR   A CD2 1 
ATOM   1826 C CE1 . TYR   A 1 237 ? -0.49564  12.68498  -6.15581  1.000 32.13263 ?  237 TYR   A CE1 1 
ATOM   1827 C CE2 . TYR   A 1 237 ? -2.25323  12.56604  -4.53589  1.000 33.10983 ?  237 TYR   A CE2 1 
ATOM   1828 C CZ  . TYR   A 1 237 ? -1.26542  13.27589  -5.17403  1.000 33.55364 ?  237 TYR   A CZ  1 
ATOM   1829 O OH  . TYR   A 1 237 ? -1.04042  14.60001  -4.84840  1.000 34.11688 ?  237 TYR   A OH  1 
ATOM   1830 N N   . ASN   A 1 238 ? -0.44794  5.94048   -5.67878  1.000 29.19497 ?  238 ASN   A N   1 
ATOM   1831 C CA  . ASN   A 1 238 ? -0.72035  4.51598   -5.82517  1.000 29.13774 ?  238 ASN   A CA  1 
ATOM   1832 C C   . ASN   A 1 238 ? -1.51760  4.22611   -7.08191  1.000 28.39325 ?  238 ASN   A C   1 
ATOM   1833 O O   . ASN   A 1 238 ? -2.36451  3.33235   -7.07885  1.000 28.54316 ?  238 ASN   A O   1 
ATOM   1834 C CB  . ASN   A 1 238 ? -1.44998  3.93655   -4.61972  1.000 32.06440 ?  238 ASN   A CB  1 
ATOM   1835 C CG  . ASN   A 1 238 ? -0.50594  3.42264   -3.58970  1.000 45.33375 ?  238 ASN   A CG  1 
ATOM   1836 O OD1 . ASN   A 1 238 ? 0.17704   2.41504   -3.80652  1.000 49.51153 ?  238 ASN   A OD1 1 
ATOM   1837 N ND2 . ASN   A 1 238 ? -0.44255  4.10991   -2.45451  1.000 50.00439 ?  238 ASN   A ND2 1 
ATOM   1838 N N   . TYR   A 1 239 ? -1.25836  5.00196   -8.13078  1.000 27.34490 ?  239 TYR   A N   1 
ATOM   1839 C CA  . TYR   A 1 239 ? -1.78187  4.74904   -9.46255  1.000 26.17524 ?  239 TYR   A CA  1 
ATOM   1840 C C   . TYR   A 1 239 ? -0.69465  4.11196   -10.31364 1.000 26.78823 ?  239 TYR   A C   1 
ATOM   1841 O O   . TYR   A 1 239 ? 0.49387   4.39082   -10.15420 1.000 29.14529 ?  239 TYR   A O   1 
ATOM   1842 C CB  . TYR   A 1 239 ? -2.26050  6.05421   -10.12001 1.000 26.40541 ?  239 TYR   A CB  1 
ATOM   1843 C CG  . TYR   A 1 239 ? -3.68448  6.44326   -9.84120  1.000 28.62030 ?  239 TYR   A CG  1 
ATOM   1844 C CD1 . TYR   A 1 239 ? -4.14703  6.61982   -8.53716  1.000 29.69094 ?  239 TYR   A CD1 1 
ATOM   1845 C CD2 . TYR   A 1 239 ? -4.57487  6.66177   -10.89939 1.000 26.87340 ?  239 TYR   A CD2 1 
ATOM   1846 C CE1 . TYR   A 1 239 ? -5.46986  6.98593   -8.29669  1.000 28.04789 ?  239 TYR   A CE1 1 
ATOM   1847 C CE2 . TYR   A 1 239 ? -5.89942  7.03622   -10.66198 1.000 30.69582 ?  239 TYR   A CE2 1 
ATOM   1848 C CZ  . TYR   A 1 239 ? -6.33381  7.19259   -9.36861  1.000 32.53982 ?  239 TYR   A CZ  1 
ATOM   1849 O OH  . TYR   A 1 239 ? -7.64902  7.54776   -9.16102  1.000 34.29611 ?  239 TYR   A OH  1 
ATOM   1850 N N   . GLU   A 1 240 ? -1.11529  3.25373   -11.23058 1.000 23.07396 ?  240 GLU   A N   1 
ATOM   1851 C CA  . GLU   A 1 240 ? -0.19493  2.62822   -12.15952 1.000 24.06658 ?  240 GLU   A CA  1 
ATOM   1852 C C   . GLU   A 1 240 ? 0.33649   3.62594   -13.18317 1.000 26.02181 ?  240 GLU   A C   1 
ATOM   1853 O O   . GLU   A 1 240 ? -0.40228  4.49144   -13.66461 1.000 28.59814 ?  240 GLU   A O   1 
ATOM   1854 C CB  . GLU   A 1 240 ? -0.90263  1.50370   -12.91313 1.000 27.47095 ?  240 GLU   A CB  1 
ATOM   1855 C CG  . GLU   A 1 240 ? -1.06796  0.25477   -12.11322 1.000 32.28045 ?  240 GLU   A CG  1 
ATOM   1856 C CD  . GLU   A 1 240 ? 0.28140   -0.37803  -11.80893 1.000 35.55966 ?  240 GLU   A CD  1 
ATOM   1857 O OE1 . GLU   A 1 240 ? 1.00896   -0.72157  -12.77524 1.000 40.79782 ?  240 GLU   A OE1 1 
ATOM   1858 O OE2 . GLU   A 1 240 ? 0.63198   -0.50549  -10.61315 1.000 39.49321 -1 240 GLU   A OE2 1 
ATOM   1859 N N   . PRO   A 1 241 ? 1.57917   3.46238   -13.61798 1.000 24.36685 ?  241 PRO   A N   1 
ATOM   1860 C CA  . PRO   A 1 241 ? 2.06109   4.27124   -14.74068 1.000 23.96231 ?  241 PRO   A CA  1 
ATOM   1861 C C   . PRO   A 1 241 ? 1.39597   3.81877   -16.02850 1.000 26.49972 ?  241 PRO   A C   1 
ATOM   1862 O O   . PRO   A 1 241 ? 1.00528   2.65853   -16.18618 1.000 28.21510 ?  241 PRO   A O   1 
ATOM   1863 C CB  . PRO   A 1 241 ? 3.56442   4.00147   -14.77320 1.000 28.89334 ?  241 PRO   A CB  1 
ATOM   1864 C CG  . PRO   A 1 241 ? 3.71935   2.67424   -14.05394 1.000 30.25334 ?  241 PRO   A CG  1 
ATOM   1865 C CD  . PRO   A 1 241 ? 2.62369   2.59295   -13.04403 1.000 26.66365 ?  241 PRO   A CD  1 
ATOM   1866 N N   . LEU   A 1 242 ? 1.29072   4.74537   -16.96134 1.000 24.00093 ?  242 LEU   A N   1 
ATOM   1867 C CA  . LEU   A 1 242 ? 0.77294   4.37602   -18.27182 1.000 23.98911 ?  242 LEU   A CA  1 
ATOM   1868 C C   . LEU   A 1 242 ? 1.88766   3.83002   -19.15566 1.000 27.64730 ?  242 LEU   A C   1 
ATOM   1869 O O   . LEU   A 1 242 ? 3.04489   4.24599   -19.06030 1.000 26.98639 ?  242 LEU   A O   1 
ATOM   1870 C CB  . LEU   A 1 242 ? 0.14065   5.58270   -18.94422 1.000 25.48905 ?  242 LEU   A CB  1 
ATOM   1871 C CG  . LEU   A 1 242 ? -1.09204  6.12261   -18.22793 1.000 25.32300 ?  242 LEU   A CG  1 
ATOM   1872 C CD1 . LEU   A 1 242 ? -1.32566  7.56919   -18.65784 1.000 28.45455 ?  242 LEU   A CD1 1 
ATOM   1873 C CD2 . LEU   A 1 242 ? -2.34018  5.25742   -18.54888 1.000 24.74214 ?  242 LEU   A CD2 1 
ATOM   1874 N N   . THR   A 1 243 ? 1.52362   2.89105   -20.01955 1.000 24.92695 ?  243 THR   A N   1 
ATOM   1875 C CA  . THR   A 1 243 ? 2.38609   2.37661   -21.07605 1.000 26.37381 ?  243 THR   A CA  1 
ATOM   1876 C C   . THR   A 1 243 ? 2.01124   3.02297   -22.41028 1.000 27.59056 ?  243 THR   A C   1 
ATOM   1877 O O   . THR   A 1 243 ? 0.96716   3.67094   -22.54727 1.000 27.15787 ?  243 THR   A O   1 
ATOM   1878 C CB  . THR   A 1 243 ? 2.23640   0.85538   -21.20758 1.000 26.48953 ?  243 THR   A CB  1 
ATOM   1879 O OG1 . THR   A 1 243 ? 0.90713   0.57033   -21.65842 1.000 26.84317 ?  243 THR   A OG1 1 
ATOM   1880 C CG2 . THR   A 1 243 ? 2.46800   0.15984   -19.87094 1.000 29.50341 ?  243 THR   A CG2 1 
ATOM   1881 N N   . GLN   A 1 244 ? 2.86037   2.79824   -23.42086 1.000 25.18344 ?  244 GLN   A N   1 
ATOM   1882 C CA  . GLN   A 1 244 ? 2.53254   3.26288   -24.76924 1.000 27.44073 ?  244 GLN   A CA  1 
ATOM   1883 C C   . GLN   A 1 244 ? 1.26803   2.57550   -25.29633 1.000 28.03897 ?  244 GLN   A C   1 
ATOM   1884 O O   . GLN   A 1 244 ? 0.44616   3.20439   -25.98783 1.000 30.14715 ?  244 GLN   A O   1 
ATOM   1885 C CB  . GLN   A 1 244 ? 3.72175   3.02095   -25.69980 1.000 30.77836 ?  244 GLN   A CB  1 
ATOM   1886 C CG  . GLN   A 1 244 ? 3.55547   3.62938   -27.10812 1.000 33.52862 ?  244 GLN   A CG  1 
ATOM   1887 C CD  . GLN   A 1 244 ? 3.30583   5.12018   -27.07648 1.000 38.63359 ?  244 GLN   A CD  1 
ATOM   1888 O OE1 . GLN   A 1 244 ? 3.86922   5.84718   -26.25070 1.000 38.68528 ?  244 GLN   A OE1 1 
ATOM   1889 N NE2 . GLN   A 1 244 ? 2.44097   5.59154   -27.98342 1.000 45.57255 ?  244 GLN   A NE2 1 
ATOM   1890 N N   . ASP   A 1 245 ? 1.07995   1.29153   -24.95150 1.000 28.12882 ?  245 ASP   A N   1 
ATOM   1891 C CA  . ASP   A 1 245 ? -0.14121  0.58079   -25.33287 1.000 27.69914 ?  245 ASP   A CA  1 
ATOM   1892 C C   . ASP   A 1 245 ? -1.38073  1.21936   -24.69746 1.000 28.72261 ?  245 ASP   A C   1 
ATOM   1893 O O   . ASP   A 1 245 ? -2.44467  1.27571   -25.32249 1.000 27.38394 ?  245 ASP   A O   1 
ATOM   1894 C CB  . ASP   A 1 245 ? -0.03811  -0.90151  -24.94931 1.000 28.70277 ?  245 ASP   A CB  1 
ATOM   1895 C CG  . ASP   A 1 245 ? 0.89189   -1.69872  -25.86706 1.000 30.11109 ?  245 ASP   A CG  1 
ATOM   1896 O OD1 . ASP   A 1 245 ? 1.39251   -1.14588  -26.86280 1.000 28.52135 ?  245 ASP   A OD1 1 
ATOM   1897 O OD2 . ASP   A 1 245 ? 1.10716   -2.90944  -25.60331 1.000 34.12351 -1 245 ASP   A OD2 1 
ATOM   1898 N N   . HIS   A 1 246 ? -1.26511  1.70667   -23.46003 1.000 27.78743 ?  246 HIS   A N   1 
ATOM   1899 C CA  . HIS   A 1 246 ? -2.39095  2.37815   -22.81371 1.000 25.63304 ?  246 HIS   A CA  1 
ATOM   1900 C C   . HIS   A 1 246 ? -2.76492  3.64364   -23.56809 1.000 27.26438 ?  246 HIS   A C   1 
ATOM   1901 O O   . HIS   A 1 246 ? -3.95048  3.93434   -23.77468 1.000 27.74279 ?  246 HIS   A O   1 
ATOM   1902 C CB  . HIS   A 1 246 ? -2.04086  2.73889   -21.36399 1.000 27.20915 ?  246 HIS   A CB  1 
ATOM   1903 C CG  . HIS   A 1 246 ? -1.95699  1.56399   -20.44410 1.000 26.73070 ?  246 HIS   A CG  1 
ATOM   1904 N ND1 . HIS   A 1 246 ? -1.20209  1.57364   -19.28813 1.000 26.89208 ?  246 HIS   A ND1 1 
ATOM   1905 C CD2 . HIS   A 1 246 ? -2.55748  0.35332   -20.49397 1.000 26.25439 ?  246 HIS   A CD2 1 
ATOM   1906 C CE1 . HIS   A 1 246 ? -1.32217  0.40780   -18.68106 1.000 28.18288 ?  246 HIS   A CE1 1 
ATOM   1907 N NE2 . HIS   A 1 246 ? -2.14508  -0.34880  -19.38778 1.000 25.96635 ?  246 HIS   A NE2 1 
ATOM   1908 N N   . VAL   A 1 247 ? -1.75814  4.44709   -23.92459 1.000 26.21120 ?  247 VAL   A N   1 
ATOM   1909 C CA  . VAL   A 1 247 ? -2.01146  5.63789   -24.72416 1.000 29.16614 ?  247 VAL   A CA  1 
ATOM   1910 C C   . VAL   A 1 247 ? -2.72353  5.25687   -26.01364 1.000 28.21516 ?  247 VAL   A C   1 
ATOM   1911 O O   . VAL   A 1 247 ? -3.70425  5.89128   -26.41521 1.000 29.67072 ?  247 VAL   A O   1 
ATOM   1912 C CB  . VAL   A 1 247 ? -0.69229  6.37900   -25.00498 1.000 29.84693 ?  247 VAL   A CB  1 
ATOM   1913 C CG1 . VAL   A 1 247 ? -0.95339  7.54545   -25.95398 1.000 31.55752 ?  247 VAL   A CG1 1 
ATOM   1914 C CG2 . VAL   A 1 247 ? -0.04781  6.85427   -23.69577 1.000 28.82121 ?  247 VAL   A CG2 1 
ATOM   1915 N N   . ASP   A 1 248 ? -2.25796  4.19955   -26.67088 1.000 29.68793 ?  248 ASP   A N   1 
ATOM   1916 C CA  . ASP   A 1 248 ? -2.88131  3.80132   -27.92990 1.000 31.96536 ?  248 ASP   A CA  1 
ATOM   1917 C C   . ASP   A 1 248 ? -4.33493  3.34211   -27.75124 1.000 31.10907 ?  248 ASP   A C   1 
ATOM   1918 O O   . ASP   A 1 248 ? -5.19624  3.68966   -28.57664 1.000 31.60032 ?  248 ASP   A O   1 
ATOM   1919 C CB  . ASP   A 1 248 ? -2.02757  2.72112   -28.59358 1.000 32.51130 ?  248 ASP   A CB  1 
ATOM   1920 C CG  . ASP   A 1 248 ? -0.60895  3.22010   -28.90987 1.000 41.59665 ?  248 ASP   A CG  1 
ATOM   1921 O OD1 . ASP   A 1 248 ? -0.41765  4.44129   -29.10700 1.000 44.81267 ?  248 ASP   A OD1 1 
ATOM   1922 O OD2 . ASP   A 1 248 ? 0.32627   2.39061   -28.95540 1.000 47.18627 -1 248 ASP   A OD2 1 
ATOM   1923 N N   . ILE   A 1 249 ? -4.64380  2.56683   -26.70049 1.000 26.42736 ?  249 ILE   A N   1 
ATOM   1924 C CA  . ILE   A 1 249 ? -6.01616  2.05574   -26.58934 1.000 26.88440 ?  249 ILE   A CA  1 
ATOM   1925 C C   . ILE   A 1 249 ? -6.99422  3.14228   -26.16883 1.000 30.67378 ?  249 ILE   A C   1 
ATOM   1926 O O   . ILE   A 1 249 ? -8.20875  2.96158   -26.33048 1.000 31.61059 ?  249 ILE   A O   1 
ATOM   1927 C CB  . ILE   A 1 249 ? -6.18475  0.85811   -25.62793 1.000 29.24302 ?  249 ILE   A CB  1 
ATOM   1928 C CG1 . ILE   A 1 249 ? -5.76122  1.21185   -24.20519 1.000 28.02154 ?  249 ILE   A CG1 1 
ATOM   1929 C CG2 . ILE   A 1 249 ? -5.48394  -0.39005  -26.15889 1.000 30.03331 ?  249 ILE   A CG2 1 
ATOM   1930 C CD1 . ILE   A 1 249 ? -6.09547  0.12175   -23.21960 1.000 34.65298 ?  249 ILE   A CD1 1 
ATOM   1931 N N   . LEU   A 1 250 ? -6.50697  4.25270   -25.61433 1.000 26.25081 ?  250 LEU   A N   1 
ATOM   1932 C CA  . LEU   A 1 250 ? -7.33541  5.42062   -25.35399 1.000 25.63564 ?  250 LEU   A CA  1 
ATOM   1933 C C   . LEU   A 1 250 ? -7.56719  6.25644   -26.60881 1.000 30.80416 ?  250 LEU   A C   1 
ATOM   1934 O O   . LEU   A 1 250 ? -8.30466  7.24129   -26.54782 1.000 29.32939 ?  250 LEU   A O   1 
ATOM   1935 C CB  . LEU   A 1 250 ? -6.70287  6.29077   -24.26436 1.000 25.68630 ?  250 LEU   A CB  1 
ATOM   1936 C CG  . LEU   A 1 250 ? -6.78192  5.76203   -22.82835 1.000 25.96062 ?  250 LEU   A CG  1 
ATOM   1937 C CD1 . LEU   A 1 250 ? -5.76857  6.44981   -21.92939 1.000 23.62919 ?  250 LEU   A CD1 1 
ATOM   1938 C CD2 . LEU   A 1 250 ? -8.17841  5.92864   -22.22121 1.000 23.99756 ?  250 LEU   A CD2 1 
ATOM   1939 N N   . GLY   A 1 251 ? -6.96059  5.88923   -27.73739 1.000 29.82614 ?  251 GLY   A N   1 
ATOM   1940 C CA  . GLY   A 1 251 ? -7.04392  6.68980   -28.94295 1.000 30.02504 ?  251 GLY   A CA  1 
ATOM   1941 C C   . GLY   A 1 251 ? -8.45909  6.94914   -29.43472 1.000 31.38949 ?  251 GLY   A C   1 
ATOM   1942 O O   . GLY   A 1 251 ? -8.82378  8.09099   -29.73667 1.000 28.71094 ?  251 GLY   A O   1 
ATOM   1943 N N   . PRO   A 1 252 ? -9.27634  5.89691   -29.55636 1.000 31.73335 ?  252 PRO   A N   1 
ATOM   1944 C CA  . PRO   A 1 252 ? -10.66124 6.11692   -30.02105 1.000 31.32912 ?  252 PRO   A CA  1 
ATOM   1945 C C   . PRO   A 1 252 ? -11.45958 7.06912   -29.14320 1.000 31.13053 ?  252 PRO   A C   1 
ATOM   1946 O O   . PRO   A 1 252 ? -12.19301 7.90827   -29.67956 1.000 29.24382 ?  252 PRO   A O   1 
ATOM   1947 C CB  . PRO   A 1 252 ? -11.24730 4.70815   -30.01479 1.000 31.61439 ?  252 PRO   A CB  1 
ATOM   1948 C CG  . PRO   A 1 252 ? -10.06406 3.82427   -30.29826 1.000 35.73028 ?  252 PRO   A CG  1 
ATOM   1949 C CD  . PRO   A 1 252 ? -8.92589  4.46262   -29.55705 1.000 33.98451 ?  252 PRO   A CD  1 
ATOM   1950 N N   . LEU   A 1 253 ? -11.34283 6.98084   -27.80920 1.000 29.03553 ?  253 LEU   A N   1 
ATOM   1951 C CA  . LEU   A 1 253 ? -12.08678 7.90451   -26.94665 1.000 24.53496 ?  253 LEU   A CA  1 
ATOM   1952 C C   . LEU   A 1 253 ? -11.53240 9.31398   -27.04250 1.000 28.38693 ?  253 LEU   A C   1 
ATOM   1953 O O   . LEU   A 1 253 ? -12.29076 10.30399  -26.98134 1.000 27.46816 ?  253 LEU   A O   1 
ATOM   1954 C CB  . LEU   A 1 253 ? -12.06349 7.40766   -25.49465 1.000 26.38161 ?  253 LEU   A CB  1 
ATOM   1955 C CG  . LEU   A 1 253 ? -12.83051 6.10085   -25.23966 1.000 30.23966 ?  253 LEU   A CG  1 
ATOM   1956 C CD1 . LEU   A 1 253 ? -12.44239 5.49759   -23.87383 1.000 29.23369 ?  253 LEU   A CD1 1 
ATOM   1957 C CD2 . LEU   A 1 253 ? -14.35087 6.32030   -25.30645 1.000 30.55860 ?  253 LEU   A CD2 1 
ATOM   1958 N N   . SER   A 1 254 ? -10.20649 9.42852   -27.20506 1.000 26.77252 ?  254 SER   A N   1 
ATOM   1959 C CA  . SER   A 1 254 ? -9.60090  10.73502  -27.42995 1.000 26.65265 ?  254 SER   A CA  1 
ATOM   1960 C C   . SER   A 1 254 ? -10.14436 11.36317  -28.70168 1.000 26.88799 ?  254 SER   A C   1 
ATOM   1961 O O   . SER   A 1 254 ? -10.51331 12.53777  -28.72378 1.000 28.63041 ?  254 SER   A O   1 
ATOM   1962 C CB  . SER   A 1 254 ? -8.07950  10.60904  -27.52153 1.000 27.55175 ?  254 SER   A CB  1 
ATOM   1963 O OG  . SER   A 1 254 ? -7.46976  11.88937  -27.56278 1.000 32.51593 ?  254 SER   A OG  1 
ATOM   1964 N N   . ALA   A 1 255 ? -10.18607 10.59213  -29.77655 1.000 28.96422 ?  255 ALA   A N   1 
ATOM   1965 C CA  . ALA   A 1 255 ? -10.69446 11.12984  -31.04060 1.000 28.21239 ?  255 ALA   A CA  1 
ATOM   1966 C C   . ALA   A 1 255 ? -12.18348 11.45167  -30.95270 1.000 29.82842 ?  255 ALA   A C   1 
ATOM   1967 O O   . ALA   A 1 255 ? -12.63371 12.47270  -31.49411 1.000 31.00872 ?  255 ALA   A O   1 
ATOM   1968 C CB  . ALA   A 1 255 ? -10.41887 10.14000  -32.16673 1.000 31.89308 ?  255 ALA   A CB  1 
ATOM   1969 N N   . GLN   A 1 256 ? -12.95734 10.62041  -30.25302 1.000 28.50613 ?  256 GLN   A N   1 
ATOM   1970 C CA  . GLN   A 1 256 ? -14.39497 10.86707  -30.11787 1.000 29.12429 ?  256 GLN   A CA  1 
ATOM   1971 C C   . GLN   A 1 256 ? -14.67992 12.16977  -29.37276 1.000 32.60009 ?  256 GLN   A C   1 
ATOM   1972 O O   . GLN   A 1 256 ? -15.62334 12.89999  -29.71598 1.000 27.40656 ?  256 GLN   A O   1 
ATOM   1973 C CB  . GLN   A 1 256 ? -15.05358 9.68210   -29.40380 1.000 29.53286 ?  256 GLN   A CB  1 
ATOM   1974 C CG  . GLN   A 1 256 ? -16.58992 9.76556   -29.32330 1.000 32.58605 ?  256 GLN   A CG  1 
ATOM   1975 C CD  . GLN   A 1 256 ? -17.20799 8.56617   -28.62326 1.000 37.53322 ?  256 GLN   A CD  1 
ATOM   1976 O OE1 . GLN   A 1 256 ? -16.55045 7.53635   -28.43625 1.000 41.17444 ?  256 GLN   A OE1 1 
ATOM   1977 N NE2 . GLN   A 1 256 ? -18.47620 8.68887   -28.22631 1.000 33.54819 ?  256 GLN   A NE2 1 
ATOM   1978 N N   . THR   A 1 257 ? -13.89041 12.47773  -28.34031 1.000 26.83649 ?  257 THR   A N   1 
ATOM   1979 C CA  . THR   A 1 257 ? -14.10415 13.68480  -27.54915 1.000 26.68301 ?  257 THR   A CA  1 
ATOM   1980 C C   . THR   A 1 257 ? -13.27807 14.88317  -28.00351 1.000 27.37996 ?  257 THR   A C   1 
ATOM   1981 O O   . THR   A 1 257 ? -13.53949 15.99702  -27.54071 1.000 31.15921 ?  257 THR   A O   1 
ATOM   1982 C CB  . THR   A 1 257 ? -13.76974 13.42380  -26.07389 1.000 27.16471 ?  257 THR   A CB  1 
ATOM   1983 O OG1 . THR   A 1 257 ? -12.37603 13.06101  -25.96311 1.000 28.49959 ?  257 THR   A OG1 1 
ATOM   1984 C CG2 . THR   A 1 257 ? -14.66069 12.32249  -25.51196 1.000 27.13397 ?  257 THR   A CG2 1 
ATOM   1985 N N   . GLY   A 1 258 ? -12.27355 14.69186  -28.85901 1.000 29.98841 ?  258 GLY   A N   1 
ATOM   1986 C CA  . GLY   A 1 258 ? -11.37945 15.79160  -29.16910 1.000 30.17282 ?  258 GLY   A CA  1 
ATOM   1987 C C   . GLY   A 1 258 ? -10.43225 16.20319  -28.05614 1.000 32.46924 ?  258 GLY   A C   1 
ATOM   1988 O O   . GLY   A 1 258 ? -9.83015  17.28037  -28.13896 1.000 33.60774 ?  258 GLY   A O   1 
ATOM   1989 N N   . ILE   A 1 259 ? -10.28918 15.37927  -27.01702 1.000 29.72248 ?  259 ILE   A N   1 
ATOM   1990 C CA  . ILE   A 1 259 ? -9.44921  15.66553  -25.85631 1.000 31.58869 ?  259 ILE   A CA  1 
ATOM   1991 C C   . ILE   A 1 259 ? -8.21370  14.77503  -25.93824 1.000 32.26103 ?  259 ILE   A C   1 
ATOM   1992 O O   . ILE   A 1 259 ? -8.32641  13.54469  -25.88233 1.000 28.15823 ?  259 ILE   A O   1 
ATOM   1993 C CB  . ILE   A 1 259 ? -10.21282 15.42403  -24.54374 1.000 25.59010 ?  259 ILE   A CB  1 
ATOM   1994 C CG1 . ILE   A 1 259 ? -11.40847 16.37804  -24.44830 1.000 27.82077 ?  259 ILE   A CG1 1 
ATOM   1995 C CG2 . ILE   A 1 259 ? -9.29171  15.60990  -23.33352 1.000 28.05227 ?  259 ILE   A CG2 1 
ATOM   1996 C CD1 . ILE   A 1 259 ? -12.36518 16.03890  -23.37498 1.000 29.94936 ?  259 ILE   A CD1 1 
ATOM   1997 N N   . ALA   A 1 260 ? -7.04134  15.39955  -26.07852 1.000 30.78398 ?  260 ALA   A N   1 
ATOM   1998 C CA  . ALA   A 1 260 ? -5.79781  14.64814  -26.18198 1.000 32.73821 ?  260 ALA   A CA  1 
ATOM   1999 C C   . ALA   A 1 260 ? -5.60386  13.79337  -24.93888 1.000 27.11595 ?  260 ALA   A C   1 
ATOM   2000 O O   . ALA   A 1 260 ? -6.00311  14.16982  -23.83865 1.000 27.59266 ?  260 ALA   A O   1 
ATOM   2001 C CB  . ALA   A 1 260 ? -4.61321  15.60177  -26.34185 1.000 31.73446 ?  260 ALA   A CB  1 
ATOM   2002 N N   . VAL   A 1 261 ? -4.99002  12.62417  -25.12505 1.000 28.79405 ?  261 VAL   A N   1 
ATOM   2003 C CA  . VAL   A 1 261 ? -4.73944  11.74961  -23.97808 1.000 27.24503 ?  261 VAL   A CA  1 
ATOM   2004 C C   . VAL   A 1 261 ? -3.99245  12.49989  -22.88262 1.000 27.13693 ?  261 VAL   A C   1 
ATOM   2005 O O   . VAL   A 1 261 ? -4.37266  12.44799  -21.71070 1.000 27.04522 ?  261 VAL   A O   1 
ATOM   2006 C CB  . VAL   A 1 261 ? -3.97760  10.48855  -24.41246 1.000 24.94973 ?  261 VAL   A CB  1 
ATOM   2007 C CG1 . VAL   A 1 261 ? -3.46523  9.72673   -23.17129 1.000 25.75868 ?  261 VAL   A CG1 1 
ATOM   2008 C CG2 . VAL   A 1 261 ? -4.88228  9.60039   -25.22330 1.000 28.50171 ?  261 VAL   A CG2 1 
ATOM   2009 N N   . LEU   A 1 262 ? -2.92757  13.22546  -23.24779 1.000 29.01208 ?  262 LEU   A N   1 
ATOM   2010 C CA  . LEU   A 1 262 ? -2.12138  13.91932  -22.23588 1.000 29.68653 ?  262 LEU   A CA  1 
ATOM   2011 C C   . LEU   A 1 262 ? -2.86337  15.08408  -21.57727 1.000 29.62592 ?  262 LEU   A C   1 
ATOM   2012 O O   . LEU   A 1 262 ? -2.58962  15.41677  -20.41418 1.000 30.93710 ?  262 LEU   A O   1 
ATOM   2013 C CB  . LEU   A 1 262 ? -0.81256  14.39553  -22.86489 1.000 30.37083 ?  262 LEU   A CB  1 
ATOM   2014 C CG  . LEU   A 1 262 ? 0.16588   13.24542  -23.13706 1.000 33.21790 ?  262 LEU   A CG  1 
ATOM   2015 C CD1 . LEU   A 1 262 ? 1.39644   13.73741  -23.86060 1.000 35.69135 ?  262 LEU   A CD1 1 
ATOM   2016 C CD2 . LEU   A 1 262 ? 0.55853   12.53912  -21.84270 1.000 31.62984 ?  262 LEU   A CD2 1 
ATOM   2017 N N   . ASP   A 1 263 ? -3.82952  15.69571  -22.27163 1.000 28.49647 ?  263 ASP   A N   1 
ATOM   2018 C CA  . ASP   A 1 263 ? -4.68615  16.66362  -21.59547 1.000 28.28763 ?  263 ASP   A CA  1 
ATOM   2019 C C   . ASP   A 1 263 ? -5.55787  15.99260  -20.54085 1.000 28.05239 ?  263 ASP   A C   1 
ATOM   2020 O O   . ASP   A 1 263 ? -5.74344  16.53270  -19.44053 1.000 31.30684 ?  263 ASP   A O   1 
ATOM   2021 C CB  . ASP   A 1 263 ? -5.58238  17.39069  -22.60719 1.000 30.18514 ?  263 ASP   A CB  1 
ATOM   2022 C CG  . ASP   A 1 263 ? -4.80451  18.27238  -23.56328 1.000 39.05620 ?  263 ASP   A CG  1 
ATOM   2023 O OD1 . ASP   A 1 263 ? -3.55354  18.34439  -23.45143 1.000 40.10417 ?  263 ASP   A OD1 1 
ATOM   2024 O OD2 . ASP   A 1 263 ? -5.46075  18.90619  -24.43692 1.000 38.26006 -1 263 ASP   A OD2 1 
ATOM   2025 N N   . MET   A 1 264 ? -6.12635  14.82038  -20.86183 1.000 28.06002 ?  264 MET   A N   1 
ATOM   2026 C CA  . MET   A 1 264 ? -6.90733  14.12126  -19.84809 1.000 24.36760 ?  264 MET   A CA  1 
ATOM   2027 C C   . MET   A 1 264 ? -6.02576  13.69187  -18.68187 1.000 26.54192 ?  264 MET   A C   1 
ATOM   2028 O O   . MET   A 1 264 ? -6.46868  13.67902  -17.52563 1.000 28.40858 ?  264 MET   A O   1 
ATOM   2029 C CB  . MET   A 1 264 ? -7.62300  12.91856  -20.46200 1.000 26.08564 ?  264 MET   A CB  1 
ATOM   2030 C CG  . MET   A 1 264 ? -8.66653  12.33418  -19.54915 1.000 25.27362 ?  264 MET   A CG  1 
ATOM   2031 S SD  . MET   A 1 264 ? -10.07135 13.46036  -19.25987 1.000 28.15653 ?  264 MET   A SD  1 
ATOM   2032 C CE  . MET   A 1 264 ? -11.14416 12.92918  -20.63710 1.000 26.33848 ?  264 MET   A CE  1 
ATOM   2033 N N   . CYS   A 1 265 ? -4.77639  13.32416  -18.96160 1.000 27.13674 ?  265 CYS   A N   1 
ATOM   2034 C CA  . CYS   A 1 265 ? -3.86354  13.00679  -17.86485 1.000 24.77309 ?  265 CYS   A CA  1 
ATOM   2035 C C   . CYS   A 1 265 ? -3.65725  14.21796  -16.96429 1.000 29.22585 ?  265 CYS   A C   1 
ATOM   2036 O O   . CYS   A 1 265 ? -3.60076  14.08652  -15.74064 1.000 27.35067 ?  265 CYS   A O   1 
ATOM   2037 C CB  . CYS   A 1 265 ? -2.51517  12.53815  -18.40912 1.000 25.80661 ?  265 CYS   A CB  1 
ATOM   2038 S SG  . CYS   A 1 265 ? -2.51996  10.91745  -19.20778 1.000 27.58560 ?  265 CYS   A SG  1 
ATOM   2039 N N   . ALA   A 1 266 ? -3.49580  15.40482  -17.55579 1.000 30.90073 ?  266 ALA   A N   1 
ATOM   2040 C CA  . ALA   A 1 266 ? -3.36438  16.60545  -16.72954 1.000 32.02201 ?  266 ALA   A CA  1 
ATOM   2041 C C   . ALA   A 1 266 ? -4.62055  16.84656  -15.89123 1.000 29.49711 ?  266 ALA   A C   1 
ATOM   2042 O O   . ALA   A 1 266 ? -4.53506  17.24040  -14.71990 1.000 32.48629 ?  266 ALA   A O   1 
ATOM   2043 C CB  . ALA   A 1 266 ? -3.04929  17.81674  -17.61763 1.000 33.50685 ?  266 ALA   A CB  1 
ATOM   2044 N N   . SER   A 1 267 ? -5.80532  16.58604  -16.46247 1.000 26.84277 ?  267 SER   A N   1 
ATOM   2045 C CA  . SER   A 1 267 ? -7.02799  16.73333  -15.67454 1.000 26.84539 ?  267 SER   A CA  1 
ATOM   2046 C C   . SER   A 1 267 ? -7.08449  15.72325  -14.52730 1.000 30.22638 ?  267 SER   A C   1 
ATOM   2047 O O   . SER   A 1 267 ? -7.44372  16.07272  -13.39177 1.000 31.46132 ?  267 SER   A O   1 
ATOM   2048 C CB  . SER   A 1 267 ? -8.25895  16.59201  -16.57741 1.000 31.26239 ?  267 SER   A CB  1 
ATOM   2049 O OG  . SER   A 1 267 ? -8.29214  17.66717  -17.50150 1.000 31.83486 ?  267 SER   A OG  1 
ATOM   2050 N N   . LEU   A 1 268 ? -6.76220  14.45511  -14.81485 1.000 27.72051 ?  268 LEU   A N   1 
ATOM   2051 C CA  . LEU   A 1 268 ? -6.70929  13.45004  -13.75940 1.000 25.70740 ?  268 LEU   A CA  1 
ATOM   2052 C C   . LEU   A 1 268 ? -5.70213  13.84205  -12.68063 1.000 28.44547 ?  268 LEU   A C   1 
ATOM   2053 O O   . LEU   A 1 268 ? -5.95819  13.66510  -11.48258 1.000 29.83554 ?  268 LEU   A O   1 
ATOM   2054 C CB  . LEU   A 1 268 ? -6.34829  12.08076  -14.35083 1.000 26.22194 ?  268 LEU   A CB  1 
ATOM   2055 C CG  . LEU   A 1 268 ? -6.15700  10.97473  -13.30037 1.000 24.10531 ?  268 LEU   A CG  1 
ATOM   2056 C CD1 . LEU   A 1 268 ? -7.39693  10.79195  -12.41104 1.000 24.17403 ?  268 LEU   A CD1 1 
ATOM   2057 C CD2 . LEU   A 1 268 ? -5.77540  9.63700   -13.98559 1.000 25.99460 ?  268 LEU   A CD2 1 
ATOM   2058 N N   . LYS   A 1 269 ? -4.54379  14.35524  -13.08644 1.000 27.71501 ?  269 LYS   A N   1 
ATOM   2059 C CA  . LYS   A 1 269 ? -3.53202  14.72760  -12.10651 1.000 29.21243 ?  269 LYS   A CA  1 
ATOM   2060 C C   . LYS   A 1 269 ? -4.06272  15.79422  -11.16510 1.000 33.28260 ?  269 LYS   A C   1 
ATOM   2061 O O   . LYS   A 1 269 ? -3.86095  15.72448  -9.94315  1.000 34.62630 ?  269 LYS   A O   1 
ATOM   2062 C CB  . LYS   A 1 269 ? -2.26347  15.20932  -12.80820 1.000 30.85079 ?  269 LYS   A CB  1 
ATOM   2063 C CG  . LYS   A 1 269 ? -1.11568  15.53572  -11.83291 1.000 36.56970 ?  269 LYS   A CG  1 
ATOM   2064 C CD  . LYS   A 1 269 ? -0.28083  16.72482  -12.30593 1.000 39.31964 ?  269 LYS   A CD  1 
ATOM   2065 C CE  . LYS   A 1 269 ? 0.71560   16.36151  -13.40312 1.000 44.85748 ?  269 LYS   A CE  1 
ATOM   2066 N NZ  . LYS   A 1 269 ? 1.59076   17.54894  -13.74669 1.000 49.60902 ?  269 LYS   A NZ  1 
ATOM   2067 N N   . GLU   A 1 270 ? -4.75490  16.79076  -11.71735 1.000 33.15147 ?  270 GLU   A N   1 
ATOM   2068 C CA  . GLU   A 1 270 ? -5.36174  17.79568  -10.85344 1.000 34.80829 ?  270 GLU   A CA  1 
ATOM   2069 C C   . GLU   A 1 270 ? -6.38093  17.16753  -9.91161  1.000 37.77529 ?  270 GLU   A C   1 
ATOM   2070 O O   . GLU   A 1 270 ? -6.45484  17.53507  -8.73173  1.000 39.26360 ?  270 GLU   A O   1 
ATOM   2071 C CB  . GLU   A 1 270 ? -6.00856  18.89976  -11.69758 1.000 37.68928 ?  270 GLU   A CB  1 
ATOM   2072 C CG  . GLU   A 1 270 ? -6.03083  20.23654  -10.97488 1.000 47.12135 ?  270 GLU   A CG  1 
ATOM   2073 C CD  . GLU   A 1 270 ? -7.08464  21.18731  -11.50537 1.000 52.04872 ?  270 GLU   A CD  1 
ATOM   2074 O OE1 . GLU   A 1 270 ? -6.92962  21.67260  -12.64827 1.000 51.96263 ?  270 GLU   A OE1 1 
ATOM   2075 O OE2 . GLU   A 1 270 ? -8.06840  21.44684  -10.77320 1.000 53.65361 -1 270 GLU   A OE2 1 
ATOM   2076 N N   . LEU   A 1 271 ? -7.18621  16.21877  -10.41235 1.000 33.43492 ?  271 LEU   A N   1 
ATOM   2077 C CA  . LEU   A 1 271 ? -8.10889  15.50779  -9.52921  1.000 33.55787 ?  271 LEU   A CA  1 
ATOM   2078 C C   . LEU   A 1 271 ? -7.36592  14.83502  -8.37942  1.000 39.58827 ?  271 LEU   A C   1 
ATOM   2079 O O   . LEU   A 1 271 ? -7.84734  14.81340  -7.24032  1.000 42.26658 ?  271 LEU   A O   1 
ATOM   2080 C CB  . LEU   A 1 271 ? -8.89278  14.46249  -10.30954 1.000 35.10926 ?  271 LEU   A CB  1 
ATOM   2081 C CG  . LEU   A 1 271 ? -9.99378  15.03887  -11.19298 1.000 32.74385 ?  271 LEU   A CG  1 
ATOM   2082 C CD1 . LEU   A 1 271 ? -10.75982 13.91260  -11.88838 1.000 32.52413 ?  271 LEU   A CD1 1 
ATOM   2083 C CD2 . LEU   A 1 271 ? -10.92216 15.88264  -10.34366 1.000 38.95744 ?  271 LEU   A CD2 1 
ATOM   2084 N N   . LEU   A 1 272 ? -6.20587  14.25508  -8.67552  1.000 34.57902 ?  272 LEU   A N   1 
ATOM   2085 C CA  . LEU   A 1 272 ? -5.44179  13.53205  -7.66406  1.000 33.55329 ?  272 LEU   A CA  1 
ATOM   2086 C C   . LEU   A 1 272 ? -4.90943  14.47693  -6.59923  1.000 39.23382 ?  272 LEU   A C   1 
ATOM   2087 O O   . LEU   A 1 272 ? -4.98701  14.18819  -5.39757  1.000 38.40200 ?  272 LEU   A O   1 
ATOM   2088 C CB  . LEU   A 1 272 ? -4.28382  12.77694  -8.31656  1.000 32.33906 ?  272 LEU   A CB  1 
ATOM   2089 C CG  . LEU   A 1 272 ? -4.71480  11.56704  -9.15918  1.000 33.87809 ?  272 LEU   A CG  1 
ATOM   2090 C CD1 . LEU   A 1 272 ? -3.49708  10.78068  -9.62585  1.000 32.67570 ?  272 LEU   A CD1 1 
ATOM   2091 C CD2 . LEU   A 1 272 ? -5.63505  10.70951  -8.33998  1.000 35.36633 ?  272 LEU   A CD2 1 
ATOM   2092 N N   . GLN   A 1 273 ? -4.32841  15.59422  -7.01392  1.000 38.47378 ?  273 GLN   A N   1 
ATOM   2093 C CA  . GLN   A 1 273 ? -3.69821  16.40463  -5.97997  1.000 44.32626 ?  273 GLN   A CA  1 
ATOM   2094 C C   . GLN   A 1 273 ? -4.66292  17.36296  -5.29793  1.000 47.47843 ?  273 GLN   A C   1 
ATOM   2095 O O   . GLN   A 1 273 ? -4.40924  17.75103  -4.15095  1.000 48.05420 ?  273 GLN   A O   1 
ATOM   2096 C CB  . GLN   A 1 273 ? -2.47131  17.15687  -6.51119  1.000 43.53784 ?  273 GLN   A CB  1 
ATOM   2097 C CG  . GLN   A 1 273 ? -2.47776  17.57746  -7.93247  1.000 45.25706 ?  273 GLN   A CG  1 
ATOM   2098 C CD  . GLN   A 1 273 ? -1.06642  17.66802  -8.49228  1.000 44.41269 ?  273 GLN   A CD  1 
ATOM   2099 O OE1 . GLN   A 1 273 ? -0.16293  16.96249  -8.04214  1.000 46.16227 ?  273 GLN   A OE1 1 
ATOM   2100 N NE2 . GLN   A 1 273 ? -0.86645  18.54290  -9.46484  1.000 42.29522 ?  273 GLN   A NE2 1 
ATOM   2101 N N   . ASN   A 1 274 ? -5.78844  17.69659  -5.92843  1.000 45.32117 ?  274 ASN   A N   1 
ATOM   2102 C CA  . ASN   A 1 274 ? -6.74810  18.61718  -5.33444  1.000 48.32585 ?  274 ASN   A CA  1 
ATOM   2103 C C   . ASN   A 1 274 ? -7.98751  17.93646  -4.77008  1.000 50.15273 ?  274 ASN   A C   1 
ATOM   2104 O O   . ASN   A 1 274 ? -8.73800  18.57759  -4.02860  1.000 53.52204 ?  274 ASN   A O   1 
ATOM   2105 C CB  . ASN   A 1 274 ? -7.17572  19.66521  -6.36360  1.000 48.93240 ?  274 ASN   A CB  1 
ATOM   2106 C CG  . ASN   A 1 274 ? -6.02857  20.54117  -6.80714  1.000 51.69594 ?  274 ASN   A CG  1 
ATOM   2107 O OD1 . ASN   A 1 274 ? -5.94600  20.93058  -7.96891  1.000 58.25554 ?  274 ASN   A OD1 1 
ATOM   2108 N ND2 . ASN   A 1 274 ? -5.13380  20.86237  -5.88118  1.000 55.11680 ?  274 ASN   A ND2 1 
ATOM   2109 N N   . GLY   A 1 275 ? -8.22993  16.67202  -5.09815  1.000 50.16094 ?  275 GLY   A N   1 
ATOM   2110 C CA  . GLY   A 1 275 ? -9.43652  16.00609  -4.65609  1.000 50.24040 ?  275 GLY   A CA  1 
ATOM   2111 C C   . GLY   A 1 275 ? -10.64970 16.38461  -5.48490  1.000 58.22700 ?  275 GLY   A C   1 
ATOM   2112 O O   . GLY   A 1 275 ? -10.58946 17.16271  -6.43827  1.000 57.30694 ?  275 GLY   A O   1 
ATOM   2113 N N   . MET   A 1 276 ? -11.78633 15.81004  -5.09592  1.000 63.69473 ?  276 MET   A N   1 
ATOM   2114 C CA  . MET   A 1 276 ? -13.04424 16.02456  -5.79909  1.000 69.41784 ?  276 MET   A CA  1 
ATOM   2115 C C   . MET   A 1 276 ? -13.83573 17.20766  -5.26367  1.000 73.28054 ?  276 MET   A C   1 
ATOM   2116 O O   . MET   A 1 276 ? -14.72609 17.70418  -5.96419  1.000 69.87214 ?  276 MET   A O   1 
ATOM   2117 C CB  . MET   A 1 276 ? -13.90707 14.76407  -5.71774  1.000 67.21810 ?  276 MET   A CB  1 
ATOM   2118 C CG  . MET   A 1 276 ? -13.22752 13.53683  -6.28794  1.000 64.21432 ?  276 MET   A CG  1 
ATOM   2119 S SD  . MET   A 1 276 ? -13.42066 13.44641  -8.07657  1.000 62.07407 ?  276 MET   A SD  1 
ATOM   2120 C CE  . MET   A 1 276 ? -14.83839 12.35363  -8.19118  1.000 48.73954 ?  276 MET   A CE  1 
ATOM   2121 N N   . ASN   A 1 277 ? -13.53437 17.66106  -4.04485  1.000 76.29355 ?  277 ASN   A N   1 
ATOM   2122 C CA  . ASN   A 1 277 ? -14.21435 18.80018  -3.42551  1.000 79.26818 ?  277 ASN   A CA  1 
ATOM   2123 C C   . ASN   A 1 277 ? -15.72365 18.57413  -3.36614  1.000 77.55935 ?  277 ASN   A C   1 
ATOM   2124 O O   . ASN   A 1 277 ? -16.52203 19.44886  -3.70717  1.000 77.89965 ?  277 ASN   A O   1 
ATOM   2125 C CB  . ASN   A 1 277 ? -13.88348 20.10614  -4.15370  1.000 80.92979 ?  277 ASN   A CB  1 
ATOM   2126 C CG  . ASN   A 1 277 ? -12.39394 20.38713  -4.19941  1.000 84.78592 ?  277 ASN   A CG  1 
ATOM   2127 O OD1 . ASN   A 1 277 ? -11.60953 19.77339  -3.47250  1.000 85.92508 ?  277 ASN   A OD1 1 
ATOM   2128 N ND2 . ASN   A 1 277 ? -11.99606 21.32388  -5.05203  1.000 89.23240 ?  277 ASN   A ND2 1 
ATOM   2129 N N   . GLY   A 1 278 ? -16.11068 17.37686  -2.93315  1.000 77.23608 ?  278 GLY   A N   1 
ATOM   2130 C CA  . GLY   A 1 278 ? -17.51716 17.05655  -2.78996  1.000 75.77928 ?  278 GLY   A CA  1 
ATOM   2131 C C   . GLY   A 1 278 ? -18.30099 17.05456  -4.07962  1.000 73.47356 ?  278 GLY   A C   1 
ATOM   2132 O O   . GLY   A 1 278 ? -19.53096 17.13136  -4.04704  1.000 72.49392 ?  278 GLY   A O   1 
ATOM   2133 N N   . ARG   A 1 279 ? -17.62744 16.98292  -5.21980  1.000 69.51171 ?  279 ARG   A N   1 
ATOM   2134 C CA  . ARG   A 1 279 ? -18.29795 16.86782  -6.50285  1.000 63.10194 ?  279 ARG   A CA  1 
ATOM   2135 C C   . ARG   A 1 279 ? -18.36079 15.40433  -6.91712  1.000 59.18489 ?  279 ARG   A C   1 
ATOM   2136 O O   . ARG   A 1 279 ? -17.70031 14.53792  -6.34121  1.000 61.17879 ?  279 ARG   A O   1 
ATOM   2137 C CB  . ARG   A 1 279 ? -17.58061 17.69862  -7.56749  1.000 60.72757 ?  279 ARG   A CB  1 
ATOM   2138 C CG  . ARG   A 1 279 ? -17.39150 19.15389  -7.19570  1.000 62.73833 ?  279 ARG   A CG  1 
ATOM   2139 C CD  . ARG   A 1 279 ? -17.51094 20.02926  -8.42474  1.000 57.75436 ?  279 ARG   A CD  1 
ATOM   2140 N NE  . ARG   A 1 279 ? -18.71483 19.70077  -9.17920  1.000 59.63583 ?  279 ARG   A NE  1 
ATOM   2141 C CZ  . ARG   A 1 279 ? -19.16465 20.38727  -10.22130 1.000 56.96553 ?  279 ARG   A CZ  1 
ATOM   2142 N NH1 . ARG   A 1 279 ? -18.54660 21.47536  -10.65247 1.000 57.78953 ?  279 ARG   A NH1 1 
ATOM   2143 N NH2 . ARG   A 1 279 ? -20.26506 19.97356  -10.84360 1.000 56.24383 ?  279 ARG   A NH2 1 
ATOM   2144 N N   . THR   A 1 280 ? -19.17892 15.12927  -7.92436  1.000 54.73865 ?  280 THR   A N   1 
ATOM   2145 C CA  . THR   A 1 280 ? -19.29985 13.78385  -8.45663  1.000 49.94325 ?  280 THR   A CA  1 
ATOM   2146 C C   . THR   A 1 280 ? -18.98703 13.78649  -9.94546  1.000 49.48995 ?  280 THR   A C   1 
ATOM   2147 O O   . THR   A 1 280 ? -19.03122 14.82625  -10.61711 1.000 42.07260 ?  280 THR   A O   1 
ATOM   2148 C CB  . THR   A 1 280 ? -20.70149 13.19302  -8.23486  1.000 51.51638 ?  280 THR   A CB  1 
ATOM   2149 O OG1 . THR   A 1 280 ? -21.65661 13.90548  -9.03464  1.000 47.08528 ?  280 THR   A OG1 1 
ATOM   2150 C CG2 . THR   A 1 280 ? -21.09589 13.27648  -6.76778  1.000 51.89381 ?  280 THR   A CG2 1 
ATOM   2151 N N   . ILE   A 1 281 ? -18.65016 12.59617  -10.43639 1.000 42.49670 ?  281 ILE   A N   1 
ATOM   2152 C CA  . ILE   A 1 281 ? -18.42368 12.33394  -11.84848 1.000 38.25095 ?  281 ILE   A CA  1 
ATOM   2153 C C   . ILE   A 1 281 ? -19.24798 11.11001  -12.20668 1.000 43.66018 ?  281 ILE   A C   1 
ATOM   2154 O O   . ILE   A 1 281 ? -19.08392 10.04825  -11.59292 1.000 40.43897 ?  281 ILE   A O   1 
ATOM   2155 C CB  . ILE   A 1 281 ? -16.93667 12.11160  -12.16795 1.000 36.68760 ?  281 ILE   A CB  1 
ATOM   2156 C CG1 . ILE   A 1 281 ? -16.13724 13.37705  -11.84932 1.000 36.64758 ?  281 ILE   A CG1 1 
ATOM   2157 C CG2 . ILE   A 1 281 ? -16.76966 11.68937  -13.61239 1.000 32.99710 ?  281 ILE   A CG2 1 
ATOM   2158 C CD1 . ILE   A 1 281 ? -14.65123 13.24049  -12.05131 1.000 36.86403 ?  281 ILE   A CD1 1 
ATOM   2159 N N   . LEU   A 1 282 ? -20.16071 11.26713  -13.17023 1.000 38.25166 ?  282 LEU   A N   1 
ATOM   2160 C CA  . LEU   A 1 282 ? -21.07841 10.19349  -13.55166 1.000 34.60090 ?  282 LEU   A CA  1 
ATOM   2161 C C   . LEU   A 1 282 ? -21.82849 9.64755   -12.33701 1.000 38.70786 ?  282 LEU   A C   1 
ATOM   2162 O O   . LEU   A 1 282 ? -22.08229 8.44906   -12.21951 1.000 41.22271 ?  282 LEU   A O   1 
ATOM   2163 C CB  . LEU   A 1 282 ? -20.34088 9.07945   -14.28655 1.000 37.92560 ?  282 LEU   A CB  1 
ATOM   2164 C CG  . LEU   A 1 282 ? -19.98073 9.38655   -15.74218 1.000 39.21875 ?  282 LEU   A CG  1 
ATOM   2165 C CD1 . LEU   A 1 282 ? -19.01885 8.35301   -16.31397 1.000 39.46555 ?  282 LEU   A CD1 1 
ATOM   2166 C CD2 . LEU   A 1 282 ? -21.24671 9.45889   -16.60424 1.000 36.74502 ?  282 LEU   A CD2 1 
ATOM   2167 N N   . GLY   A 1 283 ? -22.19030 10.54425  -11.42171 1.000 44.81394 ?  283 GLY   A N   1 
ATOM   2168 C CA  . GLY   A 1 283 ? -22.99294 10.19288  -10.27188 1.000 44.50049 ?  283 GLY   A CA  1 
ATOM   2169 C C   . GLY   A 1 283 ? -22.22018 9.78824   -9.03383  1.000 52.03642 ?  283 GLY   A C   1 
ATOM   2170 O O   . GLY   A 1 283 ? -22.81956 9.69505   -7.95467  1.000 54.57811 ?  283 GLY   A O   1 
ATOM   2171 N N   . SER   A 1 284 ? -20.91171 9.56733   -9.14048  1.000 48.99195 ?  284 SER   A N   1 
ATOM   2172 C CA  . SER   A 1 284 ? -20.13587 8.95379   -8.07202  1.000 45.76960 ?  284 SER   A CA  1 
ATOM   2173 C C   . SER   A 1 284 ? -19.04058 9.88576   -7.57823  1.000 47.58885 ?  284 SER   A C   1 
ATOM   2174 O O   . SER   A 1 284 ? -18.44501 10.63802  -8.35949  1.000 46.36741 ?  284 SER   A O   1 
ATOM   2175 C CB  . SER   A 1 284 ? -19.51691 7.64468   -8.55025  1.000 49.11077 ?  284 SER   A CB  1 
ATOM   2176 O OG  . SER   A 1 284 ? -18.40961 7.29677   -7.74894  1.000 47.79811 ?  284 SER   A OG  1 
ATOM   2177 N N   . ALA   A 1 285 ? -18.77671 9.82914   -6.27044  1.000 45.50581 ?  285 ALA   A N   1 
ATOM   2178 C CA  . ALA   A 1 285 ? -17.63442 10.52560  -5.70308  1.000 45.06888 ?  285 ALA   A CA  1 
ATOM   2179 C C   . ALA   A 1 285 ? -16.35247 9.71880   -5.82344  1.000 46.88818 ?  285 ALA   A C   1 
ATOM   2180 O O   . ALA   A 1 285 ? -15.28016 10.24565  -5.51594  1.000 44.81675 ?  285 ALA   A O   1 
ATOM   2181 C CB  . ALA   A 1 285 ? -17.88890 10.86937  -4.23318  1.000 46.72157 ?  285 ALA   A CB  1 
ATOM   2182 N N   . LEU   A 1 286 ? -16.44066 8.46978   -6.27557  1.000 41.60483 ?  286 LEU   A N   1 
ATOM   2183 C CA  . LEU   A 1 286 ? -15.28161 7.60522   -6.45328  1.000 44.68038 ?  286 LEU   A CA  1 
ATOM   2184 C C   . LEU   A 1 286 ? -14.93722 7.49706   -7.93158  1.000 36.16298 ?  286 LEU   A C   1 
ATOM   2185 O O   . LEU   A 1 286 ? -15.82997 7.43008   -8.78310  1.000 38.48826 ?  286 LEU   A O   1 
ATOM   2186 C CB  . LEU   A 1 286 ? -15.54640 6.20566   -5.89302  1.000 43.54113 ?  286 LEU   A CB  1 
ATOM   2187 C CG  . LEU   A 1 286 ? -15.95657 6.09304   -4.42874  1.000 45.36703 ?  286 LEU   A CG  1 
ATOM   2188 C CD1 . LEU   A 1 286 ? -15.86275 4.63918   -3.98355  1.000 44.99119 ?  286 LEU   A CD1 1 
ATOM   2189 C CD2 . LEU   A 1 286 ? -15.09858 6.99500   -3.55537  1.000 46.69890 ?  286 LEU   A CD2 1 
ATOM   2190 N N   . LEU   A 1 287 ? -13.64421 7.49923   -8.23745  1.000 34.18972 ?  287 LEU   A N   1 
ATOM   2191 C CA  . LEU   A 1 287 ? -13.21466 7.24202   -9.60675  1.000 31.89204 ?  287 LEU   A CA  1 
ATOM   2192 C C   . LEU   A 1 287 ? -13.21057 5.74470   -9.84877  1.000 29.73347 ?  287 LEU   A C   1 
ATOM   2193 O O   . LEU   A 1 287 ? -12.63594 4.98632   -9.05962  1.000 33.29259 ?  287 LEU   A O   1 
ATOM   2194 C CB  . LEU   A 1 287 ? -11.82881 7.82420   -9.86316  1.000 34.92829 ?  287 LEU   A CB  1 
ATOM   2195 C CG  . LEU   A 1 287 ? -11.72601 9.34177   -9.72599  1.000 34.79544 ?  287 LEU   A CG  1 
ATOM   2196 C CD1 . LEU   A 1 287 ? -10.30640 9.78014   -9.91864  1.000 32.21400 ?  287 LEU   A CD1 1 
ATOM   2197 C CD2 . LEU   A 1 287 ? -12.64507 10.02139  -10.75188 1.000 33.76696 ?  287 LEU   A CD2 1 
ATOM   2198 N N   . GLU   A 1 288 ? -13.84668 5.31886   -10.92981 1.000 26.18115 ?  288 GLU   A N   1 
ATOM   2199 C CA  . GLU   A 1 288 ? -13.97942 3.89745   -11.22261 1.000 27.32696 ?  288 GLU   A CA  1 
ATOM   2200 C C   . GLU   A 1 288 ? -12.78059 3.41839   -12.03566 1.000 26.41169 ?  288 GLU   A C   1 
ATOM   2201 O O   . GLU   A 1 288 ? -12.36302 4.08918   -12.98230 1.000 25.86961 ?  288 GLU   A O   1 
ATOM   2202 C CB  . GLU   A 1 288 ? -15.28512 3.67684   -11.98229 1.000 27.46376 ?  288 GLU   A CB  1 
ATOM   2203 C CG  . GLU   A 1 288 ? -15.43295 2.32345   -12.60134 1.000 31.88785 ?  288 GLU   A CG  1 
ATOM   2204 C CD  . GLU   A 1 288 ? -15.69784 1.26852   -11.56672 1.000 40.96252 ?  288 GLU   A CD  1 
ATOM   2205 O OE1 . GLU   A 1 288 ? -16.47971 1.57743   -10.62341 1.000 38.18424 ?  288 GLU   A OE1 1 
ATOM   2206 O OE2 . GLU   A 1 288 ? -15.10531 0.16953   -11.68804 1.000 38.59836 -1 288 GLU   A OE2 1 
ATOM   2207 N N   . ASP   A 1 289 ? -12.22902 2.22813   -11.69067 1.000 24.70081 ?  289 ASP   A N   1 
ATOM   2208 C CA  . ASP   A 1 289 ? -11.06878 1.76037   -12.44436 1.000 22.90842 ?  289 ASP   A CA  1 
ATOM   2209 C C   . ASP   A 1 289 ? -11.23029 0.33956   -12.99625 1.000 23.49147 ?  289 ASP   A C   1 
ATOM   2210 O O   . ASP   A 1 289 ? -10.23342 -0.26208  -13.38610 1.000 22.74786 ?  289 ASP   A O   1 
ATOM   2211 C CB  . ASP   A 1 289 ? -9.76650  1.88515   -11.61823 1.000 24.87593 ?  289 ASP   A CB  1 
ATOM   2212 C CG  . ASP   A 1 289 ? -9.53852  0.74806   -10.62200 1.000 26.56301 ?  289 ASP   A CG  1 
ATOM   2213 O OD1 . ASP   A 1 289 ? -10.50685 0.05809   -10.24022 1.000 26.16427 ?  289 ASP   A OD1 1 
ATOM   2214 O OD2 . ASP   A 1 289 ? -8.36091  0.59121   -10.17369 1.000 25.00256 -1 289 ASP   A OD2 1 
ATOM   2215 N N   . GLU   A 1 290 ? -12.45220 -0.18567  -13.10355 1.000 24.27204 ?  290 GLU   A N   1 
ATOM   2216 C CA  . GLU   A 1 290 ? -12.64325 -1.50336  -13.71043 1.000 25.31412 ?  290 GLU   A CA  1 
ATOM   2217 C C   . GLU   A 1 290 ? -13.50200 -1.45606  -14.97660 1.000 28.46788 ?  290 GLU   A C   1 
ATOM   2218 O O   . GLU   A 1 290 ? -14.12039 -2.45220  -15.35879 1.000 27.28046 ?  290 GLU   A O   1 
ATOM   2219 C CB  . GLU   A 1 290 ? -13.20012 -2.49299  -12.67956 1.000 28.28948 ?  290 GLU   A CB  1 
ATOM   2220 C CG  . GLU   A 1 290 ? -12.19795 -2.72157  -11.51767 1.000 27.60646 ?  290 GLU   A CG  1 
ATOM   2221 C CD  . GLU   A 1 290 ? -12.30717 -4.10675  -10.87419 1.000 34.43583 ?  290 GLU   A CD  1 
ATOM   2222 O OE1 . GLU   A 1 290 ? -13.27661 -4.84313  -11.18536 1.000 34.72383 ?  290 GLU   A OE1 1 
ATOM   2223 O OE2 . GLU   A 1 290 ? -11.41737 -4.46456  -10.05909 1.000 33.08076 -1 290 GLU   A OE2 1 
ATOM   2224 N N   . PHE   A 1 291 ? -13.50166 -0.31816  -15.67176 1.000 24.42721 ?  291 PHE   A N   1 
ATOM   2225 C CA  . PHE   A 1 291 ? -14.01964 -0.20138  -17.03461 1.000 26.41037 ?  291 PHE   A CA  1 
ATOM   2226 C C   . PHE   A 1 291 ? -12.86538 0.14403   -17.96107 1.000 28.20595 ?  291 PHE   A C   1 
ATOM   2227 O O   . PHE   A 1 291 ? -12.28159 1.22614   -17.83152 1.000 25.53310 ?  291 PHE   A O   1 
ATOM   2228 C CB  . PHE   A 1 291 ? -15.08295 0.88963   -17.13917 1.000 31.49534 ?  291 PHE   A CB  1 
ATOM   2229 C CG  . PHE   A 1 291 ? -16.39229 0.50731   -16.56052 1.000 37.44819 ?  291 PHE   A CG  1 
ATOM   2230 C CD1 . PHE   A 1 291 ? -16.74572 0.91640   -15.29180 1.000 39.46714 ?  291 PHE   A CD1 1 
ATOM   2231 C CD2 . PHE   A 1 291 ? -17.27264 -0.28095  -17.28431 1.000 33.42668 ?  291 PHE   A CD2 1 
ATOM   2232 C CE1 . PHE   A 1 291 ? -17.97588 0.55415   -14.74557 1.000 44.72916 ?  291 PHE   A CE1 1 
ATOM   2233 C CE2 . PHE   A 1 291 ? -18.49095 -0.64865  -16.75164 1.000 43.71822 ?  291 PHE   A CE2 1 
ATOM   2234 C CZ  . PHE   A 1 291 ? -18.84269 -0.23365  -15.47690 1.000 42.64864 ?  291 PHE   A CZ  1 
ATOM   2235 N N   . THR   A 1 292 ? -12.55992 -0.74416  -18.91399 1.000 26.31869 ?  292 THR   A N   1 
ATOM   2236 C CA  . THR   A 1 292 ? -11.50812 -0.46929  -19.88210 1.000 25.32297 ?  292 THR   A CA  1 
ATOM   2237 C C   . THR   A 1 292 ? -12.00913 0.48067   -20.95552 1.000 26.16522 ?  292 THR   A C   1 
ATOM   2238 O O   . THR   A 1 292 ? -13.20961 0.73861   -21.08177 1.000 27.72009 ?  292 THR   A O   1 
ATOM   2239 C CB  . THR   A 1 292 ? -11.03072 -1.75652  -20.54511 1.000 27.27379 ?  292 THR   A CB  1 
ATOM   2240 O OG1 . THR   A 1 292 ? -12.07080 -2.26749  -21.38491 1.000 29.71577 ?  292 THR   A OG1 1 
ATOM   2241 C CG2 . THR   A 1 292 ? -10.63939 -2.80911  -19.49984 1.000 28.18655 ?  292 THR   A CG2 1 
ATOM   2242 N N   . PRO   A 1 293 ? -11.10607 1.02016   -21.77102 1.000 25.28316 ?  293 PRO   A N   1 
ATOM   2243 C CA  . PRO   A 1 293 ? -11.58764 1.81155   -22.90893 1.000 28.04795 ?  293 PRO   A CA  1 
ATOM   2244 C C   . PRO   A 1 293 ? -12.51036 1.00385   -23.81185 1.000 29.59951 ?  293 PRO   A C   1 
ATOM   2245 O O   . PRO   A 1 293 ? -13.52971 1.52697   -24.27596 1.000 31.28000 ?  293 PRO   A O   1 
ATOM   2246 C CB  . PRO   A 1 293 ? -10.28909 2.22605   -23.60507 1.000 28.21524 ?  293 PRO   A CB  1 
ATOM   2247 C CG  . PRO   A 1 293 ? -9.30451  2.29014   -22.49774 1.000 28.65608 ?  293 PRO   A CG  1 
ATOM   2248 C CD  . PRO   A 1 293 ? -9.64052  1.10081   -21.63880 1.000 29.44255 ?  293 PRO   A CD  1 
ATOM   2249 N N   . PHE   A 1 294 ? -12.20548 -0.28260  -24.02220 1.000 28.44482 ?  294 PHE   A N   1 
ATOM   2250 C CA  . PHE   A 1 294 ? -13.08024 -1.13752  -24.82543 1.000 30.23574 ?  294 PHE   A CA  1 
ATOM   2251 C C   . PHE   A 1 294 ? -14.43363 -1.34230  -24.15824 1.000 34.22756 ?  294 PHE   A C   1 
ATOM   2252 O O   . PHE   A 1 294 ? -15.45340 -1.44692  -24.84750 1.000 38.03800 ?  294 PHE   A O   1 
ATOM   2253 C CB  . PHE   A 1 294 ? -12.41586 -2.49665  -25.07682 1.000 33.15624 ?  294 PHE   A CB  1 
ATOM   2254 N N   . ASP   A 1 295 ? -14.47076 -1.42608  -22.82371 1.000 31.16949 ?  295 ASP   A N   1 
ATOM   2255 C CA  . ASP   A 1 295 ? -15.75503 -1.55251  -22.13897 1.000 32.01545 ?  295 ASP   A CA  1 
ATOM   2256 C C   . ASP   A 1 295 ? -16.59804 -0.30465  -22.32478 1.000 34.11008 ?  295 ASP   A C   1 
ATOM   2257 O O   . ASP   A 1 295 ? -17.81245 -0.39235  -22.53318 1.000 37.35857 ?  295 ASP   A O   1 
ATOM   2258 C CB  . ASP   A 1 295 ? -15.55712 -1.81813  -20.65006 1.000 33.28776 ?  295 ASP   A CB  1 
ATOM   2259 C CG  . ASP   A 1 295 ? -14.84918 -3.13190  -20.38025 1.000 37.63576 ?  295 ASP   A CG  1 
ATOM   2260 O OD1 . ASP   A 1 295 ? -15.01607 -4.06247  -21.20929 1.000 38.47825 ?  295 ASP   A OD1 1 
ATOM   2261 O OD2 . ASP   A 1 295 ? -14.15548 -3.23777  -19.34853 1.000 40.33541 -1 295 ASP   A OD2 1 
ATOM   2262 N N   . VAL   A 1 296 ? -15.97380 0.86955   -22.23495 1.000 32.47225 ?  296 VAL   A N   1 
ATOM   2263 C CA  . VAL   A 1 296 ? -16.69807 2.11256   -22.46993 1.000 31.28099 ?  296 VAL   A CA  1 
ATOM   2264 C C   . VAL   A 1 296 ? -17.28476 2.12373   -23.87640 1.000 40.56790 ?  296 VAL   A C   1 
ATOM   2265 O O   . VAL   A 1 296 ? -18.47934 2.39850   -24.06509 1.000 42.51462 ?  296 VAL   A O   1 
ATOM   2266 C CB  . VAL   A 1 296 ? -15.78034 3.32656   -22.21752 1.000 32.30148 ?  296 VAL   A CB  1 
ATOM   2267 C CG1 . VAL   A 1 296 ? -16.47496 4.60740   -22.62538 1.000 34.83653 ?  296 VAL   A CG1 1 
ATOM   2268 C CG2 . VAL   A 1 296 ? -15.41502 3.38915   -20.74908 1.000 31.41268 ?  296 VAL   A CG2 1 
ATOM   2269 N N   . VAL   A 1 297 ? -16.46287 1.80427   -24.88383 1.000 35.89137 ?  297 VAL   A N   1 
ATOM   2270 C CA  . VAL   A 1 297 ? -16.96094 1.83455   -26.26044 1.000 41.16169 ?  297 VAL   A CA  1 
ATOM   2271 C C   . VAL   A 1 297 ? -18.05196 0.78694   -26.46120 1.000 42.99226 ?  297 VAL   A C   1 
ATOM   2272 O O   . VAL   A 1 297 ? -19.09097 1.05817   -27.07834 1.000 51.68182 ?  297 VAL   A O   1 
ATOM   2273 C CB  . VAL   A 1 297 ? -15.80858 1.65633   -27.26585 1.000 39.78734 ?  297 VAL   A CB  1 
ATOM   2274 C CG1 . VAL   A 1 297 ? -16.35277 1.38703   -28.65542 1.000 48.60801 ?  297 VAL   A CG1 1 
ATOM   2275 C CG2 . VAL   A 1 297 ? -14.93879 2.90804   -27.27859 1.000 46.07031 ?  297 VAL   A CG2 1 
ATOM   2276 N N   . ARG   A 1 298 ? -17.83383 -0.42555  -25.94654 1.000 45.95290 ?  298 ARG   A N   1 
ATOM   2277 C CA  . ARG   A 1 298 ? -18.78973 -1.50885  -26.14241 1.000 48.09535 ?  298 ARG   A CA  1 
ATOM   2278 C C   . ARG   A 1 298 ? -20.12912 -1.18087  -25.50006 1.000 50.46248 ?  298 ARG   A C   1 
ATOM   2279 O O   . ARG   A 1 298 ? -21.18552 -1.40859  -26.09997 1.000 56.26329 ?  298 ARG   A O   1 
ATOM   2280 C CB  . ARG   A 1 298 ? -18.20452 -2.81706  -25.59555 1.000 51.28927 ?  298 ARG   A CB  1 
ATOM   2281 C CG  . ARG   A 1 298 ? -19.15667 -3.69580  -24.79040 1.000 50.63952 ?  298 ARG   A CG  1 
ATOM   2282 C CD  . ARG   A 1 298 ? -18.56081 -5.08616  -24.52554 1.000 48.68401 ?  298 ARG   A CD  1 
ATOM   2283 N NE  . ARG   A 1 298 ? -19.61525 -6.03534  -24.18374 1.000 50.35096 ?  298 ARG   A NE  1 
ATOM   2284 C CZ  . ARG   A 1 298 ? -19.82124 -6.56467  -22.98189 1.000 44.35759 ?  298 ARG   A CZ  1 
ATOM   2285 N NH1 . ARG   A 1 298 ? -18.99047 -6.35271  -21.97244 1.000 41.44844 ?  298 ARG   A NH1 1 
ATOM   2286 N NH2 . ARG   A 1 298 ? -20.89404 -7.32478  -22.78976 1.000 39.51664 ?  298 ARG   A NH2 1 
ATOM   2287 N N   . GLN   A 1 299 ? -20.11326 -0.59265  -24.30785 1.000 49.05247 ?  299 GLN   A N   1 
ATOM   2288 C CA  . GLN   A 1 299 ? -21.36951 -0.33657  -23.62760 1.000 47.74423 ?  299 GLN   A CA  1 
ATOM   2289 C C   . GLN   A 1 299 ? -22.05055 0.94197   -24.09461 1.000 51.26020 ?  299 GLN   A C   1 
ATOM   2290 O O   . GLN   A 1 299 ? -23.27699 1.05873   -23.96770 1.000 51.72869 ?  299 GLN   A O   1 
ATOM   2291 C CB  . GLN   A 1 299 ? -21.13864 -0.28185  -22.12609 1.000 47.40321 ?  299 GLN   A CB  1 
ATOM   2292 C CG  . GLN   A 1 299 ? -22.39693 -0.44370  -21.34624 1.000 47.11723 ?  299 GLN   A CG  1 
ATOM   2293 C CD  . GLN   A 1 299 ? -22.14229 -0.45739  -19.88146 1.000 45.39047 ?  299 GLN   A CD  1 
ATOM   2294 O OE1 . GLN   A 1 299 ? -22.85582 0.18512   -19.12144 1.000 47.52647 ?  299 GLN   A OE1 1 
ATOM   2295 N NE2 . GLN   A 1 299 ? -21.11601 -1.19990  -19.45860 1.000 44.17098 ?  299 GLN   A NE2 1 
ATOM   2296 N N   . CYS   A 1 300 ? -21.30650 1.89723   -24.64165 1.000 49.52537 ?  300 CYS   A N   1 
ATOM   2297 C CA  . CYS   A 1 300 ? -21.92981 3.09990   -25.16140 1.000 50.91513 ?  300 CYS   A CA  1 
ATOM   2298 C C   . CYS   A 1 300 ? -22.25093 3.00235   -26.65062 1.000 48.32353 ?  300 CYS   A C   1 
ATOM   2299 O O   . CYS   A 1 300 ? -22.89859 3.90874   -27.17992 1.000 52.60252 ?  300 CYS   A O   1 
ATOM   2300 C CB  . CYS   A 1 300 ? -21.03721 4.31734   -24.88616 1.000 47.92701 ?  300 CYS   A CB  1 
ATOM   2301 S SG  . CYS   A 1 300 ? -20.63380 4.60202   -23.11431 1.000 59.96349 ?  300 CYS   A SG  1 
ATOM   2302 N N   . SER   A 1 301 ? -21.85544 1.90822   -27.33184 1.000 51.65506 ?  301 SER   A N   1 
ATOM   2303 C CA  . SER   A 1 301 ? -22.01255 1.79214   -28.78555 1.000 49.81832 ?  301 SER   A CA  1 
ATOM   2304 C C   . SER   A 1 301 ? -22.64993 0.49989   -29.29758 1.000 58.21529 ?  301 SER   A C   1 
ATOM   2305 O O   . SER   A 1 301 ? -22.90873 0.41229   -30.50355 1.000 59.22024 ?  301 SER   A O   1 
ATOM   2306 C CB  . SER   A 1 301 ? -20.65265 1.94360   -29.48854 1.000 51.68693 ?  301 SER   A CB  1 
ATOM   2307 O OG  . SER   A 1 301 ? -20.12786 3.25044   -29.34043 1.000 52.15573 ?  301 SER   A OG  1 
ATOM   2308 N N   . GLY   A 1 302 ? -22.89562 -0.50132  -28.45690 1.000 56.47738 ?  302 GLY   A N   1 
ATOM   2309 C CA  . GLY   A 1 302 ? -23.59129 -1.68442  -28.93456 1.000 62.40747 ?  302 GLY   A CA  1 
ATOM   2310 C C   . GLY   A 1 302 ? -22.94931 -3.00004  -28.54388 1.000 72.21347 ?  302 GLY   A C   1 
ATOM   2311 O O   . GLY   A 1 302 ? -22.76610 -3.27961  -27.35430 1.000 74.54740 ?  302 GLY   A O   1 
ATOM   2312 N N   . VAL   A 1 303 ? -22.61322 -3.82355  -29.53275 1.000 77.56579 ?  303 VAL   A N   1 
ATOM   2313 C CA  . VAL   A 1 303 ? -21.96006 -5.10059  -29.26954 1.000 81.61141 ?  303 VAL   A CA  1 
ATOM   2314 C C   . VAL   A 1 303 ? -20.50139 -4.86918  -28.89146 1.000 87.18576 ?  303 VAL   A C   1 
ATOM   2315 O O   . VAL   A 1 303 ? -19.68388 -4.50079  -29.73294 1.000 86.78119 ?  303 VAL   A O   1 
ATOM   2316 C CB  . VAL   A 1 303 ? -22.07133 -6.04555  -30.47809 1.000 86.90415 ?  303 VAL   A CB  1 
ATOM   2317 C CG1 . VAL   A 1 303 ? -22.90534 -7.26993  -30.12404 1.000 80.01911 ?  303 VAL   A CG1 1 
ATOM   2318 C CG2 . VAL   A 1 303 ? -22.67479 -5.31063  -31.66490 1.000 91.91345 ?  303 VAL   A CG2 1 
ATOM   2319 N N   . SER   B 1 1   ? 39.93182  -17.31441 -1.02876  1.000 38.05647 ?  1   SER   B N   1 
ATOM   2320 C CA  . SER   B 1 1   ? 39.56463  -15.96983 -0.59606  1.000 40.80229 ?  1   SER   B CA  1 
ATOM   2321 C C   . SER   B 1 1   ? 39.54544  -14.96455 -1.73760  1.000 39.74207 ?  1   SER   B C   1 
ATOM   2322 O O   . SER   B 1 1   ? 39.78237  -15.31392 -2.89874  1.000 35.34115 ?  1   SER   B O   1 
ATOM   2323 C CB  . SER   B 1 1   ? 40.51804  -15.48123 0.49537   1.000 46.81682 ?  1   SER   B CB  1 
ATOM   2324 O OG  . SER   B 1 1   ? 39.85543  -15.52135 1.76326   1.000 52.03027 ?  1   SER   B OG  1 
ATOM   2325 N N   . GLY   B 1 2   ? 39.25808  -13.71089 -1.37854  1.000 39.54386 ?  2   GLY   B N   1 
ATOM   2326 C CA  . GLY   B 1 2   ? 39.06939  -12.63540 -2.32849  1.000 35.32691 ?  2   GLY   B CA  1 
ATOM   2327 C C   . GLY   B 1 2   ? 37.59856  -12.37552 -2.60645  1.000 33.05014 ?  2   GLY   B C   1 
ATOM   2328 O O   . GLY   B 1 2   ? 36.73799  -13.24079 -2.46028  1.000 39.01277 ?  2   GLY   B O   1 
ATOM   2329 N N   . PHE   B 1 3   ? 37.29671  -11.14405 -3.01086  1.000 37.52461 ?  3   PHE   B N   1 
ATOM   2330 C CA  . PHE   B 1 3   ? 35.91070  -10.79767 -3.31501  1.000 39.06018 ?  3   PHE   B CA  1 
ATOM   2331 C C   . PHE   B 1 3   ? 35.83440  -9.93315  -4.56537  1.000 34.72652 ?  3   PHE   B C   1 
ATOM   2332 O O   . PHE   B 1 3   ? 36.41629  -8.84665  -4.61354  1.000 36.22413 ?  3   PHE   B O   1 
ATOM   2333 C CB  . PHE   B 1 3   ? 35.24733  -10.09811 -2.12444  1.000 36.81763 ?  3   PHE   B CB  1 
ATOM   2334 C CG  . PHE   B 1 3   ? 33.77400  -10.10981 -2.20579  1.000 37.24430 ?  3   PHE   B CG  1 
ATOM   2335 C CD1 . PHE   B 1 3   ? 33.07393  -11.28144 -1.98517  1.000 39.83455 ?  3   PHE   B CD1 1 
ATOM   2336 C CD2 . PHE   B 1 3   ? 33.07520  -8.96270  -2.53963  1.000 37.53284 ?  3   PHE   B CD2 1 
ATOM   2337 C CE1 . PHE   B 1 3   ? 31.69785  -11.30683 -2.08475  1.000 38.65485 ?  3   PHE   B CE1 1 
ATOM   2338 C CE2 . PHE   B 1 3   ? 31.70352  -8.98576  -2.63407  1.000 35.69403 ?  3   PHE   B CE2 1 
ATOM   2339 C CZ  . PHE   B 1 3   ? 31.01748  -10.15995 -2.41117  1.000 37.96300 ?  3   PHE   B CZ  1 
ATOM   2340 N N   . ARG   B 1 4   ? 35.08229  -10.39418 -5.56654  1.000 32.20418 ?  4   ARG   B N   1 
ATOM   2341 C CA  . ARG   B 1 4   ? 35.03071  -9.73034  -6.85965  1.000 32.89113 ?  4   ARG   B CA  1 
ATOM   2342 C C   . ARG   B 1 4   ? 33.59129  -9.71031  -7.35585  1.000 27.18984 ?  4   ARG   B C   1 
ATOM   2343 O O   . ARG   B 1 4   ? 32.83420  -10.65022 -7.11790  1.000 31.27129 ?  4   ARG   B O   1 
ATOM   2344 C CB  . ARG   B 1 4   ? 35.92001  -10.45260 -7.89415  1.000 28.86626 ?  4   ARG   B CB  1 
ATOM   2345 C CG  . ARG   B 1 4   ? 37.40285  -10.02729 -7.92529  1.000 33.84495 ?  4   ARG   B CG  1 
ATOM   2346 C CD  . ARG   B 1 4   ? 37.63863  -8.83892  -8.91300  1.000 32.03681 ?  4   ARG   B CD  1 
ATOM   2347 N NE  . ARG   B 1 4   ? 39.06480  -8.61410  -9.16207  1.000 33.81039 ?  4   ARG   B NE  1 
ATOM   2348 C CZ  . ARG   B 1 4   ? 39.57435  -7.45622  -9.57299  1.000 39.40824 ?  4   ARG   B CZ  1 
ATOM   2349 N NH1 . ARG   B 1 4   ? 38.79536  -6.42519  -9.86155  1.000 38.75990 ?  4   ARG   B NH1 1 
ATOM   2350 N NH2 . ARG   B 1 4   ? 40.89836  -7.32167  -9.68131  1.000 34.35397 ?  4   ARG   B NH2 1 
ATOM   2351 N N   . LYS   B 1 5   ? 33.22755  -8.64147  -8.05290  1.000 30.18626 ?  5   LYS   B N   1 
ATOM   2352 C CA  . LYS   B 1 5   ? 31.96494  -8.63443  -8.77875  1.000 31.24556 ?  5   LYS   B CA  1 
ATOM   2353 C C   . LYS   B 1 5   ? 32.08460  -9.66199  -9.89704  1.000 27.09748 ?  5   LYS   B C   1 
ATOM   2354 O O   . LYS   B 1 5   ? 33.00963  -9.59079  -10.71006 1.000 28.92149 ?  5   LYS   B O   1 
ATOM   2355 C CB  . LYS   B 1 5   ? 31.67618  -7.23054  -9.32431  1.000 35.16334 ?  5   LYS   B CB  1 
ATOM   2356 C CG  . LYS   B 1 5   ? 30.25217  -6.97702  -9.83737  1.000 38.44755 ?  5   LYS   B CG  1 
ATOM   2357 C CD  . LYS   B 1 5   ? 29.25506  -6.62723  -8.72665  1.000 40.88827 ?  5   LYS   B CD  1 
ATOM   2358 C CE  . LYS   B 1 5   ? 29.48832  -5.24058  -8.11071  1.000 38.77825 ?  5   LYS   B CE  1 
ATOM   2359 N NZ  . LYS   B 1 5   ? 28.70762  -4.12674  -8.75199  1.000 38.88584 ?  5   LYS   B NZ  1 
ATOM   2360 N N   . MET   B 1 6   ? 31.18133  -10.63341 -9.91681  1.000 25.27540 ?  6   MET   B N   1 
ATOM   2361 C CA  . MET   B 1 6   ? 31.30539  -11.79829 -10.77169 1.000 24.51835 ?  6   MET   B CA  1 
ATOM   2362 C C   . MET   B 1 6   ? 29.98722  -12.03002 -11.49916 1.000 28.61924 ?  6   MET   B C   1 
ATOM   2363 O O   . MET   B 1 6   ? 28.91547  -11.88630 -10.90078 1.000 28.46715 ?  6   MET   B O   1 
ATOM   2364 C CB  . MET   B 1 6   ? 31.67227  -13.00793 -9.91535  1.000 29.72579 ?  6   MET   B CB  1 
ATOM   2365 C CG  . MET   B 1 6   ? 32.40560  -14.09798 -10.60029 1.000 34.47326 ?  6   MET   B CG  1 
ATOM   2366 S SD  . MET   B 1 6   ? 32.70076  -15.34002 -9.30525  1.000 37.80338 ?  6   MET   B SD  1 
ATOM   2367 C CE  . MET   B 1 6   ? 33.94775  -14.58437 -8.29735  1.000 35.50416 ?  6   MET   B CE  1 
ATOM   2368 N N   . ALA   B 1 7   ? 30.06785  -12.34815 -12.78938 1.000 24.85898 ?  7   ALA   B N   1 
ATOM   2369 C CA  . ALA   B 1 7   ? 28.90426  -12.69034 -13.58990 1.000 22.96126 ?  7   ALA   B CA  1 
ATOM   2370 C C   . ALA   B 1 7   ? 28.84702  -14.20212 -13.75521 1.000 25.11018 ?  7   ALA   B C   1 
ATOM   2371 O O   . ALA   B 1 7   ? 29.84625  -14.90343 -13.54265 1.000 25.95481 ?  7   ALA   B O   1 
ATOM   2372 C CB  . ALA   B 1 7   ? 28.96195  -12.00270 -14.96689 1.000 24.03394 ?  7   ALA   B CB  1 
ATOM   2373 N N   . PHE   B 1 8   ? 27.65921  -14.70816 -14.09282 1.000 22.80291 ?  8   PHE   B N   1 
ATOM   2374 C CA  . PHE   B 1 8   ? 27.54293  -16.09836 -14.51168 1.000 25.99828 ?  8   PHE   B CA  1 
ATOM   2375 C C   . PHE   B 1 8   ? 28.26110  -16.29946 -15.84291 1.000 24.44808 ?  8   PHE   B C   1 
ATOM   2376 O O   . PHE   B 1 8   ? 28.34562  -15.37361 -16.65988 1.000 25.40587 ?  8   PHE   B O   1 
ATOM   2377 C CB  . PHE   B 1 8   ? 26.08105  -16.54072 -14.64753 1.000 24.38533 ?  8   PHE   B CB  1 
ATOM   2378 C CG  . PHE   B 1 8   ? 25.39886  -16.77568 -13.32458 1.000 28.97530 ?  8   PHE   B CG  1 
ATOM   2379 C CD1 . PHE   B 1 8   ? 25.73036  -17.87156 -12.54540 1.000 31.52037 ?  8   PHE   B CD1 1 
ATOM   2380 C CD2 . PHE   B 1 8   ? 24.46358  -15.87338 -12.83714 1.000 28.97854 ?  8   PHE   B CD2 1 
ATOM   2381 C CE1 . PHE   B 1 8   ? 25.11910  -18.08419 -11.31934 1.000 31.64051 ?  8   PHE   B CE1 1 
ATOM   2382 C CE2 . PHE   B 1 8   ? 23.85002  -16.08806 -11.61521 1.000 29.66830 ?  8   PHE   B CE2 1 
ATOM   2383 C CZ  . PHE   B 1 8   ? 24.17502  -17.19691 -10.86325 1.000 31.22409 ?  8   PHE   B CZ  1 
ATOM   2384 N N   . PRO   B 1 9   ? 28.85231  -17.47515 -16.05242 1.000 26.21308 ?  9   PRO   B N   1 
ATOM   2385 C CA  . PRO   B 1 9   ? 29.41158  -17.78261 -17.36592 1.000 25.83878 ?  9   PRO   B CA  1 
ATOM   2386 C C   . PRO   B 1 9   ? 28.30898  -17.66658 -18.39262 1.000 24.23950 ?  9   PRO   B C   1 
ATOM   2387 O O   . PRO   B 1 9   ? 27.20881  -18.18309 -18.18940 1.000 27.96024 ?  9   PRO   B O   1 
ATOM   2388 C CB  . PRO   B 1 9   ? 29.88453  -19.23578 -17.23073 1.000 26.42357 ?  9   PRO   B CB  1 
ATOM   2389 C CG  . PRO   B 1 9   ? 30.04577  -19.44365 -15.73265 1.000 28.74687 ?  9   PRO   B CG  1 
ATOM   2390 C CD  . PRO   B 1 9   ? 28.96489  -18.60905 -15.11854 1.000 24.44649 ?  9   PRO   B CD  1 
ATOM   2391 N N   . SER   B 1 10  ? 28.63869  -17.05098 -19.51522 1.000 24.50755 ?  10  SER   B N   1 
ATOM   2392 C CA  . SER   B 1 10  ? 27.63258  -16.61127 -20.48153 1.000 23.08647 ?  10  SER   B CA  1 
ATOM   2393 C C   . SER   B 1 10  ? 27.42920  -17.55566 -21.66613 1.000 25.82665 ?  10  SER   B C   1 
ATOM   2394 O O   . SER   B 1 10  ? 26.55744  -17.27785 -22.50479 1.000 25.09466 ?  10  SER   B O   1 
ATOM   2395 C CB  . SER   B 1 10  ? 27.99890  -15.22020 -20.98837 1.000 24.94397 ?  10  SER   B CB  1 
ATOM   2396 O OG  . SER   B 1 10  ? 29.28758  -15.20598 -21.59221 1.000 25.43399 ?  10  SER   B OG  1 
ATOM   2397 N N   . GLY   B 1 11  ? 28.18293  -18.66041 -21.75377 1.000 24.99899 ?  11  GLY   B N   1 
ATOM   2398 C CA  . GLY   B 1 11  ? 28.08978  -19.53314 -22.93389 1.000 28.50831 ?  11  GLY   B CA  1 
ATOM   2399 C C   . GLY   B 1 11  ? 26.67268  -19.94953 -23.30130 1.000 28.84050 ?  11  GLY   B C   1 
ATOM   2400 O O   . GLY   B 1 11  ? 26.27301  -19.89808 -24.48097 1.000 28.40692 ?  11  GLY   B O   1 
ATOM   2401 N N   . LYS   B 1 12  ? 25.88717  -20.37251 -22.30494 1.000 24.62206 ?  12  LYS   B N   1 
ATOM   2402 C CA  . LYS   B 1 12  ? 24.53850  -20.84175 -22.60572 1.000 26.10784 ?  12  LYS   B CA  1 
ATOM   2403 C C   . LYS   B 1 12  ? 23.68730  -19.75900 -23.24889 1.000 29.06947 ?  12  LYS   B C   1 
ATOM   2404 O O   . LYS   B 1 12  ? 22.79387  -20.07432 -24.03951 1.000 27.22262 ?  12  LYS   B O   1 
ATOM   2405 C CB  . LYS   B 1 12  ? 23.84482  -21.37026 -21.35325 1.000 28.37394 ?  12  LYS   B CB  1 
ATOM   2406 C CG  . LYS   B 1 12  ? 24.44442  -22.67881 -20.81204 1.000 33.05870 ?  12  LYS   B CG  1 
ATOM   2407 C CD  . LYS   B 1 12  ? 23.74112  -23.12464 -19.52733 1.000 32.34400 ?  12  LYS   B CD  1 
ATOM   2408 C CE  . LYS   B 1 12  ? 24.09201  -24.56004 -19.14913 1.000 37.97057 ?  12  LYS   B CE  1 
ATOM   2409 N NZ  . LYS   B 1 12  ? 25.52582  -24.72152 -18.76873 1.000 46.25851 ?  12  LYS   B NZ  1 
ATOM   2410 N N   . VAL   B 1 13  ? 23.95390  -18.48910 -22.93672 1.000 25.10182 ?  13  VAL   B N   1 
ATOM   2411 C CA  . VAL   B 1 13  ? 23.20009  -17.38528 -23.53080 1.000 23.16371 ?  13  VAL   B CA  1 
ATOM   2412 C C   . VAL   B 1 13  ? 23.80433  -16.97977 -24.86904 1.000 25.84440 ?  13  VAL   B C   1 
ATOM   2413 O O   . VAL   B 1 13  ? 23.07788  -16.65767 -25.81488 1.000 29.34111 ?  13  VAL   B O   1 
ATOM   2414 C CB  . VAL   B 1 13  ? 23.15211  -16.19132 -22.54746 1.000 24.90586 ?  13  VAL   B CB  1 
ATOM   2415 C CG1 . VAL   B 1 13  ? 22.37421  -15.04009 -23.18576 1.000 25.76390 ?  13  VAL   B CG1 1 
ATOM   2416 C CG2 . VAL   B 1 13  ? 22.48104  -16.62959 -21.26014 1.000 25.96156 ?  13  VAL   B CG2 1 
ATOM   2417 N N   . GLU   B 1 14  ? 25.13962  -16.98834 -24.97288 1.000 24.19528 ?  14  GLU   B N   1 
ATOM   2418 C CA  . GLU   B 1 14  ? 25.79888  -16.68958 -26.24243 1.000 25.04958 ?  14  GLU   B CA  1 
ATOM   2419 C C   . GLU   B 1 14  ? 25.24243  -17.54275 -27.37343 1.000 26.97400 ?  14  GLU   B C   1 
ATOM   2420 O O   . GLU   B 1 14  ? 25.08614  -17.05479 -28.50499 1.000 26.31232 ?  14  GLU   B O   1 
ATOM   2421 C CB  . GLU   B 1 14  ? 27.29988  -16.92632 -26.12890 1.000 26.02404 ?  14  GLU   B CB  1 
ATOM   2422 C CG  . GLU   B 1 14  ? 28.00624  -15.96993 -25.20202 1.000 24.65179 ?  14  GLU   B CG  1 
ATOM   2423 C CD  . GLU   B 1 14  ? 29.44646  -16.37536 -24.98328 1.000 26.90400 ?  14  GLU   B CD  1 
ATOM   2424 O OE1 . GLU   B 1 14  ? 30.16433  -16.57896 -25.98707 1.000 28.51016 ?  14  GLU   B OE1 1 
ATOM   2425 O OE2 . GLU   B 1 14  ? 29.84641  -16.48756 -23.81592 1.000 25.73254 -1 14  GLU   B OE2 1 
ATOM   2426 N N   . GLY   B 1 15  ? 24.98097  -18.83091 -27.09273 1.000 28.29653 ?  15  GLY   B N   1 
ATOM   2427 C CA  . GLY   B 1 15  ? 24.41353  -19.69279 -28.14644 1.000 29.58228 ?  15  GLY   B CA  1 
ATOM   2428 C C   . GLY   B 1 15  ? 23.00190  -19.35083 -28.57262 1.000 32.68983 ?  15  GLY   B C   1 
ATOM   2429 O O   . GLY   B 1 15  ? 22.46128  -20.01281 -29.46815 1.000 32.53912 ?  15  GLY   B O   1 
ATOM   2430 N N   . CYS   B 1 16  ? 22.39005  -18.33414 -27.96781 1.000 26.20761 ?  16  CYS   B N   1 
ATOM   2431 C CA  . CYS   B 1 16  ? 21.03828  -17.91931 -28.29499 1.000 28.62960 ?  16  CYS   B CA  1 
ATOM   2432 C C   . CYS   B 1 16  ? 20.95157  -16.56836 -28.97596 1.000 29.27334 ?  16  CYS   B C   1 
ATOM   2433 O O   . CYS   B 1 16  ? 19.84940  -16.14799 -29.32256 1.000 29.34236 ?  16  CYS   B O   1 
ATOM   2434 C CB  . CYS   B 1 16  ? 20.18044  -17.88119 -27.02302 1.000 28.84859 ?  16  CYS   B CB  1 
ATOM   2435 S SG  . CYS   B 1 16  ? 20.01807  -19.43806 -26.17154 1.000 32.23350 ?  16  CYS   B SG  1 
ATOM   2436 N N   . MET   B 1 17  ? 22.05572  -15.84238 -29.12833 1.000 26.45090 ?  17  MET   B N   1 
ATOM   2437 C CA  . MET   B 1 17  ? 21.95110  -14.48750 -29.64695 1.000 27.70809 ?  17  MET   B CA  1 
ATOM   2438 C C   . MET   B 1 17  ? 21.95733  -14.48384 -31.16847 1.000 30.04140 ?  17  MET   B C   1 
ATOM   2439 O O   . MET   B 1 17  ? 22.72608  -15.22265 -31.79979 1.000 28.70954 ?  17  MET   B O   1 
ATOM   2440 C CB  . MET   B 1 17  ? 23.08450  -13.61536 -29.12763 1.000 27.10616 ?  17  MET   B CB  1 
ATOM   2441 C CG  . MET   B 1 17  ? 23.11643  -13.49515 -27.59005 1.000 25.10266 ?  17  MET   B CG  1 
ATOM   2442 S SD  . MET   B 1 17  ? 21.55328  -13.05470 -26.79506 1.000 27.95589 ?  17  MET   B SD  1 
ATOM   2443 C CE  . MET   B 1 17  ? 21.17839  -11.52937 -27.62831 1.000 29.52574 ?  17  MET   B CE  1 
ATOM   2444 N N   . VAL   B 1 18  ? 21.09013  -13.64141 -31.74848 1.000 29.53616 ?  18  VAL   B N   1 
ATOM   2445 C CA  . VAL   B 1 18  ? 21.00199  -13.44148 -33.19343 1.000 28.26975 ?  18  VAL   B CA  1 
ATOM   2446 C C   . VAL   B 1 18  ? 20.83645  -11.95225 -33.48635 1.000 31.58516 ?  18  VAL   B C   1 
ATOM   2447 O O   . VAL   B 1 18  ? 20.58353  -11.13830 -32.59891 1.000 28.19478 ?  18  VAL   B O   1 
ATOM   2448 C CB  . VAL   B 1 18  ? 19.84287  -14.26017 -33.82828 1.000 31.55617 ?  18  VAL   B CB  1 
ATOM   2449 C CG1 . VAL   B 1 18  ? 19.99117  -15.74260 -33.52940 1.000 30.87235 ?  18  VAL   B CG1 1 
ATOM   2450 C CG2 . VAL   B 1 18  ? 18.49415  -13.76518 -33.32786 1.000 30.53135 ?  18  VAL   B CG2 1 
ATOM   2451 N N   . GLN   B 1 19  ? 20.98986  -11.58913 -34.75669 1.000 31.34909 ?  19  GLN   B N   1 
ATOM   2452 C CA  . GLN   B 1 19  ? 20.75445  -10.23227 -35.21798 1.000 30.36851 ?  19  GLN   B CA  1 
ATOM   2453 C C   . GLN   B 1 19  ? 19.37361  -10.15490 -35.86271 1.000 33.35689 ?  19  GLN   B C   1 
ATOM   2454 O O   . GLN   B 1 19  ? 18.97752  -11.07838 -36.57698 1.000 35.53347 ?  19  GLN   B O   1 
ATOM   2455 C CB  . GLN   B 1 19  ? 21.83172  -9.82817  -36.22865 1.000 32.87890 ?  19  GLN   B CB  1 
ATOM   2456 C CG  . GLN   B 1 19  ? 21.70046  -8.43914  -36.76573 1.000 34.41398 ?  19  GLN   B CG  1 
ATOM   2457 C CD  . GLN   B 1 19  ? 22.73982  -8.14005  -37.83293 1.000 42.45674 ?  19  GLN   B CD  1 
ATOM   2458 O OE1 . GLN   B 1 19  ? 23.68165  -7.40219  -37.59687 1.000 42.98469 ?  19  GLN   B OE1 1 
ATOM   2459 N NE2 . GLN   B 1 19  ? 22.55787  -8.70716  -39.01824 1.000 47.28737 ?  19  GLN   B NE2 1 
ATOM   2460 N N   . VAL   B 1 20  ? 18.64570  -9.06498  -35.59744 1.000 30.08941 ?  20  VAL   B N   1 
ATOM   2461 C CA  . VAL   B 1 20  ? 17.31679  -8.82301  -36.16353 1.000 33.48155 ?  20  VAL   B CA  1 
ATOM   2462 C C   . VAL   B 1 20  ? 17.30721  -7.45388  -36.82963 1.000 31.81662 ?  20  VAL   B C   1 
ATOM   2463 O O   . VAL   B 1 20  ? 17.60186  -6.43241  -36.19765 1.000 31.56524 ?  20  VAL   B O   1 
ATOM   2464 C CB  . VAL   B 1 20  ? 16.20375  -8.91311  -35.09771 1.000 32.30160 ?  20  VAL   B CB  1 
ATOM   2465 C CG1 . VAL   B 1 20  ? 14.83945  -8.66050  -35.74196 1.000 32.29477 ?  20  VAL   B CG1 1 
ATOM   2466 C CG2 . VAL   B 1 20  ? 16.21790  -10.28220 -34.42455 1.000 31.22547 ?  20  VAL   B CG2 1 
ATOM   2467 N N   . THR   B 1 21  ? 16.92893  -7.41816  -38.10683 1.000 35.70800 ?  21  THR   B N   1 
ATOM   2468 C CA  . THR   B 1 21  ? 16.92971  -6.18684  -38.87492 1.000 34.11072 ?  21  THR   B CA  1 
ATOM   2469 C C   . THR   B 1 21  ? 15.55303  -6.00613  -39.49111 1.000 34.61466 ?  21  THR   B C   1 
ATOM   2470 O O   . THR   B 1 21  ? 14.95496  -6.96858  -39.97903 1.000 36.42953 ?  21  THR   B O   1 
ATOM   2471 C CB  . THR   B 1 21  ? 18.01100  -6.20030  -39.98901 1.000 39.75640 ?  21  THR   B CB  1 
ATOM   2472 O OG1 . THR   B 1 21  ? 19.31525  -6.16961  -39.40120 1.000 39.04223 ?  21  THR   B OG1 1 
ATOM   2473 C CG2 . THR   B 1 21  ? 17.87099  -4.99901  -40.90425 1.000 37.68500 ?  21  THR   B CG2 1 
ATOM   2474 N N   . CYS   B 1 22  ? 15.04331  -4.78270  -39.40723 1.000 34.28898 ?  22  CYS   B N   1 
ATOM   2475 C CA  . CYS   B 1 22  ? 13.81822  -4.38914  -40.09648 1.000 38.09865 ?  22  CYS   B CA  1 
ATOM   2476 C C   . CYS   B 1 22  ? 14.06422  -3.01006  -40.68672 1.000 37.60006 ?  22  CYS   B C   1 
ATOM   2477 O O   . CYS   B 1 22  ? 14.37374  -2.06380  -39.95410 1.000 38.22786 ?  22  CYS   B O   1 
ATOM   2478 C CB  . CYS   B 1 22  ? 12.62726  -4.39160  -39.13548 1.000 38.82241 ?  22  CYS   B CB  1 
ATOM   2479 S SG  . CYS   B 1 22  ? 11.02122  -4.18469  -39.91981 1.000 44.38840 ?  22  CYS   B SG  1 
ATOM   2480 N N   . GLY   B 1 23  ? 13.97044  -2.90652  -42.01016 1.000 43.36760 ?  23  GLY   B N   1 
ATOM   2481 C CA  . GLY   B 1 23  ? 14.31891  -1.65640  -42.66491 1.000 46.75107 ?  23  GLY   B CA  1 
ATOM   2482 C C   . GLY   B 1 23  ? 15.76610  -1.29737  -42.39170 1.000 41.58673 ?  23  GLY   B C   1 
ATOM   2483 O O   . GLY   B 1 23  ? 16.68852  -2.07515  -42.66047 1.000 45.16085 ?  23  GLY   B O   1 
ATOM   2484 N N   . THR   B 1 24  ? 15.97541  -0.10026  -41.85391 1.000 37.42795 ?  24  THR   B N   1 
ATOM   2485 C CA  . THR   B 1 24  ? 17.29784  0.37821   -41.48812 1.000 45.63633 ?  24  THR   B CA  1 
ATOM   2486 C C   . THR   B 1 24  ? 17.55680  0.27640   -39.98599 1.000 41.71151 ?  24  THR   B C   1 
ATOM   2487 O O   . THR   B 1 24  ? 18.49257  0.91090   -39.48005 1.000 43.60528 ?  24  THR   B O   1 
ATOM   2488 C CB  . THR   B 1 24  ? 17.47941  1.82113   -41.95478 1.000 47.06492 ?  24  THR   B CB  1 
ATOM   2489 O OG1 . THR   B 1 24  ? 16.61264  2.67485   -41.20461 1.000 50.07613 ?  24  THR   B OG1 1 
ATOM   2490 C CG2 . THR   B 1 24  ? 17.13114  1.94622   -43.44095 1.000 48.88264 ?  24  THR   B CG2 1 
ATOM   2491 N N   . THR   B 1 25  ? 16.74451  -0.49064  -39.25835 1.000 38.93995 ?  25  THR   B N   1 
ATOM   2492 C CA  . THR   B 1 25  ? 16.93248  -0.66129  -37.81684 1.000 40.39519 ?  25  THR   B CA  1 
ATOM   2493 C C   . THR   B 1 25  ? 17.42480  -2.07315  -37.51624 1.000 34.67455 ?  25  THR   B C   1 
ATOM   2494 O O   . THR   B 1 25  ? 16.80047  -3.05664  -37.91810 1.000 35.37365 ?  25  THR   B O   1 
ATOM   2495 C CB  . THR   B 1 25  ? 15.63816  -0.37504  -37.04358 1.000 43.06052 ?  25  THR   B CB  1 
ATOM   2496 O OG1 . THR   B 1 25  ? 15.17182  0.94521   -37.36097 1.000 40.77325 ?  25  THR   B OG1 1 
ATOM   2497 C CG2 . THR   B 1 25  ? 15.89819  -0.45521  -35.53372 1.000 36.09706 ?  25  THR   B CG2 1 
ATOM   2498 N N   . THR   B 1 26  ? 18.53441  -2.17242  -36.78154 1.000 35.75675 ?  26  THR   B N   1 
ATOM   2499 C CA  . THR   B 1 26  ? 19.12901  -3.45787  -36.44686 1.000 34.97579 ?  26  THR   B CA  1 
ATOM   2500 C C   . THR   B 1 26  ? 19.34678  -3.51249  -34.94221 1.000 26.93058 ?  26  THR   B C   1 
ATOM   2501 O O   . THR   B 1 26  ? 19.80518  -2.53344  -34.34980 1.000 30.56226 ?  26  THR   B O   1 
ATOM   2502 C CB  . THR   B 1 26  ? 20.46955  -3.66444  -37.18702 1.000 37.12703 ?  26  THR   B CB  1 
ATOM   2503 O OG1 . THR   B 1 26  ? 20.23372  -3.72074  -38.60107 1.000 40.60992 ?  26  THR   B OG1 1 
ATOM   2504 C CG2 . THR   B 1 26  ? 21.12851  -4.94756  -36.77414 1.000 36.52766 ?  26  THR   B CG2 1 
ATOM   2505 N N   . LEU   B 1 27  ? 18.98547  -4.63600  -34.33336 1.000 30.80462 ?  27  LEU   B N   1 
ATOM   2506 C CA  . LEU   B 1 27  ? 19.32479  -4.87999  -32.92056 1.000 26.75488 ?  27  LEU   B CA  1 
ATOM   2507 C C   . LEU   B 1 27  ? 19.49277  -6.38240  -32.70083 1.000 26.32095 ?  27  LEU   B C   1 
ATOM   2508 O O   . LEU   B 1 27  ? 19.64224  -7.15719  -33.64813 1.000 28.92935 ?  27  LEU   B O   1 
ATOM   2509 C CB  . LEU   B 1 27  ? 18.27001  -4.25249  -31.99472 1.000 26.39637 ?  27  LEU   B CB  1 
ATOM   2510 C CG  . LEU   B 1 27  ? 16.78916  -4.40986  -32.37419 1.000 26.96086 ?  27  LEU   B CG  1 
ATOM   2511 C CD1 . LEU   B 1 27  ? 16.31100  -5.85449  -32.34322 1.000 26.36522 ?  27  LEU   B CD1 1 
ATOM   2512 C CD2 . LEU   B 1 27  ? 15.95938  -3.53238  -31.43645 1.000 26.74741 ?  27  LEU   B CD2 1 
ATOM   2513 N N   . ASN   B 1 28  ? 19.52166  -6.80448  -31.42633 1.000 26.38478 ?  28  ASN   B N   1 
ATOM   2514 C CA  . ASN   B 1 28  ? 19.76445  -8.19382  -31.07018 1.000 23.42107 ?  28  ASN   B CA  1 
ATOM   2515 C C   . ASN   B 1 28  ? 18.46613  -8.90822  -30.72000 1.000 23.82134 ?  28  ASN   B C   1 
ATOM   2516 O O   . ASN   B 1 28  ? 17.53868  -8.29935  -30.18880 1.000 26.11518 ?  28  ASN   B O   1 
ATOM   2517 C CB  . ASN   B 1 28  ? 20.72308  -8.27850  -29.85983 1.000 21.42695 ?  28  ASN   B CB  1 
ATOM   2518 C CG  . ASN   B 1 28  ? 21.97586  -7.46154  -30.06383 1.000 24.85424 ?  28  ASN   B CG  1 
ATOM   2519 O OD1 . ASN   B 1 28  ? 22.89352  -7.88358  -30.76551 1.000 29.22708 ?  28  ASN   B OD1 1 
ATOM   2520 N ND2 . ASN   B 1 28  ? 22.02586  -6.29500  -29.46639 1.000 25.90852 ?  28  ASN   B ND2 1 
ATOM   2521 N N   . GLY   B 1 29  ? 18.41935  -10.21066 -31.01157 1.000 25.89273 ?  29  GLY   B N   1 
ATOM   2522 C CA  . GLY   B 1 29  ? 17.33629  -11.05782 -30.56801 1.000 25.38592 ?  29  GLY   B CA  1 
ATOM   2523 C C   . GLY   B 1 29  ? 17.84051  -12.28734 -29.82479 1.000 25.54361 ?  29  GLY   B C   1 
ATOM   2524 O O   . GLY   B 1 29  ? 18.98745  -12.70659 -29.95327 1.000 28.36569 ?  29  GLY   B O   1 
ATOM   2525 N N   . LEU   B 1 30  ? 16.92056  -12.89019 -29.08308 1.000 24.10004 ?  30  LEU   B N   1 
ATOM   2526 C CA  . LEU   B 1 30  ? 17.15938  -14.06122 -28.27572 1.000 26.67288 ?  30  LEU   B CA  1 
ATOM   2527 C C   . LEU   B 1 30  ? 16.40491  -15.22656 -28.89414 1.000 29.58369 ?  30  LEU   B C   1 
ATOM   2528 O O   . LEU   B 1 30  ? 15.17781  -15.21362 -28.92472 1.000 28.01577 ?  30  LEU   B O   1 
ATOM   2529 C CB  . LEU   B 1 30  ? 16.69208  -13.81642 -26.84085 1.000 26.42299 ?  30  LEU   B CB  1 
ATOM   2530 C CG  . LEU   B 1 30  ? 16.97710  -14.96047 -25.86878 1.000 27.01561 ?  30  LEU   B CG  1 
ATOM   2531 C CD1 . LEU   B 1 30  ? 18.45271  -14.99373 -25.46241 1.000 27.74956 ?  30  LEU   B CD1 1 
ATOM   2532 C CD2 . LEU   B 1 30  ? 16.06020  -14.83733 -24.62730 1.000 27.04029 ?  30  LEU   B CD2 1 
ATOM   2533 N N   . TRP   B 1 31  ? 17.13155  -16.22706 -29.37079 1.000 27.50081 ?  31  TRP   B N   1 
ATOM   2534 C CA  . TRP   B 1 31  ? 16.55504  -17.31848 -30.16333 1.000 29.91479 ?  31  TRP   B CA  1 
ATOM   2535 C C   . TRP   B 1 31  ? 16.46712  -18.55856 -29.27666 1.000 28.96156 ?  31  TRP   B C   1 
ATOM   2536 O O   . TRP   B 1 31  ? 17.49286  -19.16174 -28.92573 1.000 31.21982 ?  31  TRP   B O   1 
ATOM   2537 C CB  . TRP   B 1 31  ? 17.40983  -17.54360 -31.41293 1.000 29.69347 ?  31  TRP   B CB  1 
ATOM   2538 C CG  . TRP   B 1 31  ? 17.03114  -18.70183 -32.31563 1.000 30.42533 ?  31  TRP   B CG  1 
ATOM   2539 C CD1 . TRP   B 1 31  ? 15.78705  -19.21868 -32.51909 1.000 36.38549 ?  31  TRP   B CD1 1 
ATOM   2540 C CD2 . TRP   B 1 31  ? 17.92131  -19.44859 -33.15778 1.000 34.51639 ?  31  TRP   B CD2 1 
ATOM   2541 N NE1 . TRP   B 1 31  ? 15.84382  -20.26159 -33.43066 1.000 36.47511 ?  31  TRP   B NE1 1 
ATOM   2542 C CE2 . TRP   B 1 31  ? 17.14200  -20.42246 -33.83482 1.000 34.68205 ?  31  TRP   B CE2 1 
ATOM   2543 C CE3 . TRP   B 1 31  ? 19.30393  -19.41045 -33.38651 1.000 32.98982 ?  31  TRP   B CE3 1 
ATOM   2544 C CZ2 . TRP   B 1 31  ? 17.69970  -21.33463 -34.72933 1.000 37.45835 ?  31  TRP   B CZ2 1 
ATOM   2545 C CZ3 . TRP   B 1 31  ? 19.85587  -20.32229 -34.28033 1.000 36.74842 ?  31  TRP   B CZ3 1 
ATOM   2546 C CH2 . TRP   B 1 31  ? 19.05107  -21.26657 -34.94160 1.000 39.89943 ?  31  TRP   B CH2 1 
ATOM   2547 N N   . LEU   B 1 32  ? 15.24244  -18.92859 -28.89822 1.000 28.18215 ?  32  LEU   B N   1 
ATOM   2548 C CA  . LEU   B 1 32  ? 14.97052  -20.07752 -28.04307 1.000 27.60180 ?  32  LEU   B CA  1 
ATOM   2549 C C   . LEU   B 1 32  ? 13.96600  -20.97109 -28.74925 1.000 31.63735 ?  32  LEU   B C   1 
ATOM   2550 O O   . LEU   B 1 32  ? 12.90348  -20.49907 -29.16193 1.000 33.13237 ?  32  LEU   B O   1 
ATOM   2551 C CB  . LEU   B 1 32  ? 14.39012  -19.66083 -26.68801 1.000 30.26857 ?  32  LEU   B CB  1 
ATOM   2552 C CG  . LEU   B 1 32  ? 15.27402  -18.69714 -25.89709 1.000 29.24926 ?  32  LEU   B CG  1 
ATOM   2553 C CD1 . LEU   B 1 32  ? 14.47044  -18.12113 -24.73533 1.000 30.53787 ?  32  LEU   B CD1 1 
ATOM   2554 C CD2 . LEU   B 1 32  ? 16.48097  -19.43904 -25.41316 1.000 32.00027 ?  32  LEU   B CD2 1 
ATOM   2555 N N   . ASP   B 1 33  ? 14.28545  -22.25910 -28.84436 1.000 34.21836 ?  33  ASP   B N   1 
ATOM   2556 C CA  . ASP   B 1 33  ? 13.48741  -23.21833 -29.63563 1.000 37.89057 ?  33  ASP   B CA  1 
ATOM   2557 C C   . ASP   B 1 33  ? 13.29821  -22.60135 -31.01931 1.000 36.94882 ?  33  ASP   B C   1 
ATOM   2558 O O   . ASP   B 1 33  ? 14.29789  -22.21770 -31.64385 1.000 39.62763 ?  33  ASP   B O   1 
ATOM   2559 C CB  . ASP   B 1 33  ? 12.21533  -23.55626 -28.88111 1.000 38.99207 ?  33  ASP   B CB  1 
ATOM   2560 C CG  . ASP   B 1 33  ? 12.49333  -24.23130 -27.56316 1.000 42.83693 ?  33  ASP   B CG  1 
ATOM   2561 O OD1 . ASP   B 1 33  ? 13.36981  -25.11980 -27.51564 1.000 47.85856 ?  33  ASP   B OD1 1 
ATOM   2562 O OD2 . ASP   B 1 33  ? 11.85077  -23.85909 -26.55902 1.000 46.98021 -1 33  ASP   B OD2 1 
ATOM   2563 N N   . ASP   B 1 34  ? 12.06592  -22.47955 -31.53397 1.000 36.87002 ?  34  ASP   B N   1 
ATOM   2564 C CA  . ASP   B 1 34  ? 11.85242  -21.87299 -32.84205 1.000 34.02133 ?  34  ASP   B CA  1 
ATOM   2565 C C   . ASP   B 1 34  ? 11.29521  -20.45539 -32.75304 1.000 35.69462 ?  34  ASP   B C   1 
ATOM   2566 O O   . ASP   B 1 34  ? 10.62401  -19.99567 -33.67771 1.000 35.36953 ?  34  ASP   B O   1 
ATOM   2567 C CB  . ASP   B 1 34  ? 10.94703  -22.75406 -33.71966 1.000 39.74223 ?  34  ASP   B CB  1 
ATOM   2568 C CG  . ASP   B 1 34  ? 9.55466   -22.96358 -33.12725 1.000 45.05066 ?  34  ASP   B CG  1 
ATOM   2569 O OD1 . ASP   B 1 34  ? 9.37306   -22.80204 -31.89558 1.000 42.41402 ?  34  ASP   B OD1 1 
ATOM   2570 O OD2 . ASP   B 1 34  ? 8.63953   -23.32882 -33.90346 1.000 46.66616 -1 34  ASP   B OD2 1 
ATOM   2571 N N   . VAL   B 1 35  ? 11.60437  -19.71096 -31.68071 1.000 34.61770 ?  35  VAL   B N   1 
ATOM   2572 C CA  . VAL   B 1 35  ? 11.11360  -18.34333 -31.55160 1.000 27.79834 ?  35  VAL   B CA  1 
ATOM   2573 C C   . VAL   B 1 35  ? 12.28239  -17.40046 -31.25989 1.000 29.13750 ?  35  VAL   B C   1 
ATOM   2574 O O   . VAL   B 1 35  ? 13.17069  -17.73970 -30.47963 1.000 31.02396 ?  35  VAL   B O   1 
ATOM   2575 C CB  . VAL   B 1 35  ? 10.04364  -18.23554 -30.44323 1.000 31.97730 ?  35  VAL   B CB  1 
ATOM   2576 C CG1 . VAL   B 1 35  ? 9.59390   -16.77053 -30.25992 1.000 32.00068 ?  35  VAL   B CG1 1 
ATOM   2577 C CG2 . VAL   B 1 35  ? 8.84649   -19.10819 -30.77801 1.000 36.52182 ?  35  VAL   B CG2 1 
ATOM   2578 N N   . VAL   B 1 36  ? 12.26276  -16.21356 -31.86614 1.000 29.48766 ?  36  VAL   B N   1 
ATOM   2579 C CA  . VAL   B 1 36  ? 13.22563  -15.14613 -31.60148 1.000 28.60092 ?  36  VAL   B CA  1 
ATOM   2580 C C   . VAL   B 1 36  ? 12.50185  -13.98246 -30.92605 1.000 31.30544 ?  36  VAL   B C   1 
ATOM   2581 O O   . VAL   B 1 36  ? 11.49662  -13.48437 -31.43968 1.000 27.85505 ?  36  VAL   B O   1 
ATOM   2582 C CB  . VAL   B 1 36  ? 13.91694  -14.67368 -32.89227 1.000 28.73733 ?  36  VAL   B CB  1 
ATOM   2583 C CG1 . VAL   B 1 36  ? 14.83285  -13.46728 -32.58850 1.000 29.28209 ?  36  VAL   B CG1 1 
ATOM   2584 C CG2 . VAL   B 1 36  ? 14.72125  -15.79803 -33.51776 1.000 32.12428 ?  36  VAL   B CG2 1 
ATOM   2585 N N   . TYR   B 1 37  ? 13.02718  -13.52763 -29.79028 1.000 25.85822 ?  37  TYR   B N   1 
ATOM   2586 C CA  . TYR   B 1 37  ? 12.44606  -12.43652 -29.00927 1.000 27.23625 ?  37  TYR   B CA  1 
ATOM   2587 C C   . TYR   B 1 37  ? 13.33509  -11.21077 -29.15466 1.000 27.00445 ?  37  TYR   B C   1 
ATOM   2588 O O   . TYR   B 1 37  ? 14.55273  -11.32953 -29.01555 1.000 28.86790 ?  37  TYR   B O   1 
ATOM   2589 C CB  . TYR   B 1 37  ? 12.35631  -12.81943 -27.51902 1.000 27.81564 ?  37  TYR   B CB  1 
ATOM   2590 C CG  . TYR   B 1 37  ? 11.61155  -14.11130 -27.23422 1.000 28.21290 ?  37  TYR   B CG  1 
ATOM   2591 C CD1 . TYR   B 1 37  ? 12.19331  -15.34480 -27.50369 1.000 26.50681 ?  37  TYR   B CD1 1 
ATOM   2592 C CD2 . TYR   B 1 37  ? 10.33207  -14.09485 -26.68065 1.000 29.71111 ?  37  TYR   B CD2 1 
ATOM   2593 C CE1 . TYR   B 1 37  ? 11.52303  -16.53130 -27.24724 1.000 30.21723 ?  37  TYR   B CE1 1 
ATOM   2594 C CE2 . TYR   B 1 37  ? 9.65386   -15.27469 -26.41738 1.000 30.64599 ?  37  TYR   B CE2 1 
ATOM   2595 C CZ  . TYR   B 1 37  ? 10.25086  -16.48700 -26.71508 1.000 34.47334 ?  37  TYR   B CZ  1 
ATOM   2596 O OH  . TYR   B 1 37  ? 9.57934   -17.66748 -26.47933 1.000 37.39266 ?  37  TYR   B OH  1 
ATOM   2597 N N   . CYS   B 1 38  ? 12.75276  -10.03963 -29.41156 1.000 23.59863 ?  38  CYS   B N   1 
ATOM   2598 C CA  . CYS   B 1 38  ? 13.56230  -8.83016  -29.53879 1.000 26.46244 ?  38  CYS   B CA  1 
ATOM   2599 C C   . CYS   B 1 38  ? 12.69923  -7.62399  -29.18692 1.000 24.53663 ?  38  CYS   B C   1 
ATOM   2600 O O   . CYS   B 1 38  ? 11.48028  -7.75635  -29.06036 1.000 27.03914 ?  38  CYS   B O   1 
ATOM   2601 C CB  . CYS   B 1 38  ? 14.16419  -8.69556  -30.95027 1.000 24.72418 ?  38  CYS   B CB  1 
ATOM   2602 S SG  . CYS   B 1 38  ? 12.94757  -8.30169  -32.24339 1.000 29.14232 ?  38  CYS   B SG  1 
ATOM   2603 N N   . PRO   B 1 39  ? 13.30099  -6.45702  -28.94486 1.000 24.17475 ?  39  PRO   B N   1 
ATOM   2604 C CA  . PRO   B 1 39  ? 12.49107  -5.26782  -28.64706 1.000 21.76143 ?  39  PRO   B CA  1 
ATOM   2605 C C   . PRO   B 1 39  ? 11.63678  -4.88813  -29.85905 1.000 27.02742 ?  39  PRO   B C   1 
ATOM   2606 O O   . PRO   B 1 39  ? 12.10169  -4.91927  -31.00086 1.000 26.58429 ?  39  PRO   B O   1 
ATOM   2607 C CB  . PRO   B 1 39  ? 13.53457  -4.19245  -28.33224 1.000 27.05149 ?  39  PRO   B CB  1 
ATOM   2608 C CG  . PRO   B 1 39  ? 14.70115  -5.01295  -27.75000 1.000 24.85444 ?  39  PRO   B CG  1 
ATOM   2609 C CD  . PRO   B 1 39  ? 14.73508  -6.22509  -28.65056 1.000 23.80425 ?  39  PRO   B CD  1 
ATOM   2610 N N   . ARG   B 1 40  ? 10.38245  -4.52177  -29.59777 1.000 25.31080 ?  40  ARG   B N   1 
ATOM   2611 C CA  . ARG   B 1 40  ? 9.47878   -4.22539  -30.72144 1.000 26.10104 ?  40  ARG   B CA  1 
ATOM   2612 C C   . ARG   B 1 40  ? 9.85689   -2.95967  -31.49296 1.000 30.85069 ?  40  ARG   B C   1 
ATOM   2613 O O   . ARG   B 1 40  ? 9.43523   -2.81374  -32.65065 1.000 31.31192 ?  40  ARG   B O   1 
ATOM   2614 C CB  . ARG   B 1 40  ? 8.03510   -4.13831  -30.21241 1.000 26.85763 ?  40  ARG   B CB  1 
ATOM   2615 C CG  . ARG   B 1 40  ? 7.77698   -2.96207  -29.30558 1.000 24.66452 ?  40  ARG   B CG  1 
ATOM   2616 C CD  . ARG   B 1 40  ? 6.31544   -2.92787  -28.86056 1.000 24.96716 ?  40  ARG   B CD  1 
ATOM   2617 N NE  . ARG   B 1 40  ? 6.03763   -1.82377  -27.95246 1.000 23.57901 ?  40  ARG   B NE  1 
ATOM   2618 C CZ  . ARG   B 1 40  ? 4.83695   -1.51125  -27.48267 1.000 26.77301 ?  40  ARG   B CZ  1 
ATOM   2619 N NH1 . ARG   B 1 40  ? 3.75526   -2.19980  -27.83503 1.000 28.62194 ?  40  ARG   B NH1 1 
ATOM   2620 N NH2 . ARG   B 1 40  ? 4.71463   -0.46184  -26.67344 1.000 24.70028 ?  40  ARG   B NH2 1 
ATOM   2621 N N   . HIS   B 1 41  ? 10.65847  -2.04715  -30.92112 1.000 27.06473 ?  41  HIS   B N   1 
ATOM   2622 C CA  . HIS   B 1 41  ? 10.97431  -0.84029  -31.66883 1.000 28.11553 ?  41  HIS   B CA  1 
ATOM   2623 C C   . HIS   B 1 41  ? 11.89326  -1.10359  -32.85296 1.000 32.03280 ?  41  HIS   B C   1 
ATOM   2624 O O   . HIS   B 1 41  ? 12.22665  -0.14955  -33.56260 1.000 36.78466 ?  41  HIS   B O   1 
ATOM   2625 C CB  . HIS   B 1 41  ? 11.58219  0.24405   -30.77500 1.000 29.58112 ?  41  HIS   B CB  1 
ATOM   2626 C CG  . HIS   B 1 41  ? 12.90961  -0.12030  -30.18944 1.000 32.36648 ?  41  HIS   B CG  1 
ATOM   2627 N ND1 . HIS   B 1 41  ? 13.04705  -0.57476  -28.89390 1.000 30.01866 ?  41  HIS   B ND1 1 
ATOM   2628 C CD2 . HIS   B 1 41  ? 14.15707  -0.07795  -30.71349 1.000 35.82531 ?  41  HIS   B CD2 1 
ATOM   2629 C CE1 . HIS   B 1 41  ? 14.32475  -0.81785  -28.65427 1.000 29.75976 ?  41  HIS   B CE1 1 
ATOM   2630 N NE2 . HIS   B 1 41  ? 15.02193  -0.51934  -29.73765 1.000 28.14392 ?  41  HIS   B NE2 1 
ATOM   2631 N N   . VAL   B 1 42  ? 12.27972  -2.35400  -33.10639 1.000 27.70069 ?  42  VAL   B N   1 
ATOM   2632 C CA  . VAL   B 1 42  ? 12.96632  -2.67211  -34.35667 1.000 31.09658 ?  42  VAL   B CA  1 
ATOM   2633 C C   . VAL   B 1 42  ? 12.05434  -2.42418  -35.54804 1.000 35.43186 ?  42  VAL   B C   1 
ATOM   2634 O O   . VAL   B 1 42  ? 12.54261  -2.21882  -36.66573 1.000 35.32731 ?  42  VAL   B O   1 
ATOM   2635 C CB  . VAL   B 1 42  ? 13.47716  -4.12368  -34.36439 1.000 31.46710 ?  42  VAL   B CB  1 
ATOM   2636 C CG1 . VAL   B 1 42  ? 12.33957  -5.14753  -34.42953 1.000 31.42602 ?  42  VAL   B CG1 1 
ATOM   2637 C CG2 . VAL   B 1 42  ? 14.46046  -4.33747  -35.51059 1.000 34.20348 ?  42  VAL   B CG2 1 
ATOM   2638 N N   . ILE   B 1 43  ? 10.73267  -2.42863  -35.34272 1.000 32.82598 ?  43  ILE   B N   1 
ATOM   2639 C CA  . ILE   B 1 43  ? 9.85444   -2.15037  -36.48819 1.000 34.18155 ?  43  ILE   B CA  1 
ATOM   2640 C C   . ILE   B 1 43  ? 9.72591   -0.66698  -36.77738 1.000 36.37264 ?  43  ILE   B C   1 
ATOM   2641 O O   . ILE   B 1 43  ? 9.04256   -0.28732  -37.74043 1.000 42.37591 ?  43  ILE   B O   1 
ATOM   2642 C CB  . ILE   B 1 43  ? 8.44978   -2.75830  -36.29744 1.000 32.42818 ?  43  ILE   B CB  1 
ATOM   2643 C CG1 . ILE   B 1 43  ? 7.70305   -2.06353  -35.16716 1.000 35.48929 ?  43  ILE   B CG1 1 
ATOM   2644 C CG2 . ILE   B 1 43  ? 8.53404   -4.24757  -36.06044 1.000 35.16384 ?  43  ILE   B CG2 1 
ATOM   2645 C CD1 . ILE   B 1 43  ? 6.27432   -2.56252  -35.01024 1.000 34.11553 ?  43  ILE   B CD1 1 
ATOM   2646 N N   . CYS   B 1 44  ? 10.37783  0.19389   -36.00864 1.000 35.05832 ?  44  CYS   B N   1 
ATOM   2647 C CA  . CYS   B 1 44  ? 10.23050  1.63196   -36.16497 1.000 38.83790 ?  44  CYS   B CA  1 
ATOM   2648 C C   . CYS   B 1 44  ? 11.31545  2.21444   -37.06261 1.000 47.03821 ?  44  CYS   B C   1 
ATOM   2649 O O   . CYS   B 1 44  ? 12.48750  1.83389   -36.97153 1.000 42.40365 ?  44  CYS   B O   1 
ATOM   2650 C CB  . CYS   B 1 44  ? 10.28328  2.33741   -34.81200 1.000 43.78390 ?  44  CYS   B CB  1 
ATOM   2651 S SG  . CYS   B 1 44  ? 8.92934   1.96596   -33.69789 1.000 42.39716 ?  44  CYS   B SG  1 
ATOM   2652 N N   . THR   B 1 45  ? 10.91601  3.14710   -37.92353 1.000 44.69528 ?  45  THR   B N   1 
ATOM   2653 C CA  . THR   B 1 45  ? 11.86432  4.07203   -38.51618 1.000 48.28697 ?  45  THR   B CA  1 
ATOM   2654 C C   . THR   B 1 45  ? 12.21247  5.15240   -37.49607 1.000 51.65029 ?  45  THR   B C   1 
ATOM   2655 O O   . THR   B 1 45  ? 11.54749  5.30657   -36.46939 1.000 51.53909 ?  45  THR   B O   1 
ATOM   2656 C CB  . THR   B 1 45  ? 11.29242  4.71402   -39.78259 1.000 49.67433 ?  45  THR   B CB  1 
ATOM   2657 O OG1 . THR   B 1 45  ? 10.33383  5.71468   -39.41727 1.000 48.07947 ?  45  THR   B OG1 1 
ATOM   2658 C CG2 . THR   B 1 45  ? 10.62181  3.67017   -40.66327 1.000 50.11535 ?  45  THR   B CG2 1 
ATOM   2659 N N   . SER   B 1 46  ? 13.27015  5.91453   -37.78788 1.000 55.91711 ?  46  SER   B N   1 
ATOM   2660 C CA  . SER   B 1 46  ? 13.66424  6.98980   -36.88254 1.000 57.91977 ?  46  SER   B CA  1 
ATOM   2661 C C   . SER   B 1 46  ? 12.52071  7.97300   -36.65863 1.000 59.78296 ?  46  SER   B C   1 
ATOM   2662 O O   . SER   B 1 46  ? 12.43254  8.59337   -35.59164 1.000 60.36477 ?  46  SER   B O   1 
ATOM   2663 C CB  . SER   B 1 46  ? 14.89775  7.71799   -37.42587 1.000 58.67551 ?  46  SER   B CB  1 
ATOM   2664 O OG  . SER   B 1 46  ? 14.54171  8.65171   -38.43344 1.000 63.39870 ?  46  SER   B OG  1 
ATOM   2665 N N   . GLU   B 1 47  ? 11.63153  8.11536   -37.64323 1.000 56.90193 ?  47  GLU   B N   1 
ATOM   2666 C CA  . GLU   B 1 47  ? 10.45875  8.96614   -37.48874 1.000 60.27002 ?  47  GLU   B CA  1 
ATOM   2667 C C   . GLU   B 1 47  ? 9.37927   8.28731   -36.65013 1.000 54.84897 ?  47  GLU   B C   1 
ATOM   2668 O O   . GLU   B 1 47  ? 8.69803   8.94954   -35.85906 1.000 54.56957 ?  47  GLU   B O   1 
ATOM   2669 C CB  . GLU   B 1 47  ? 9.91258   9.34333   -38.86792 1.000 63.99837 ?  47  GLU   B CB  1 
ATOM   2670 C CG  . GLU   B 1 47  ? 8.74250   10.31981  -38.84988 1.000 69.95212 ?  47  GLU   B CG  1 
ATOM   2671 C CD  . GLU   B 1 47  ? 8.07434   10.45497  -40.21055 1.000 79.40441 ?  47  GLU   B CD  1 
ATOM   2672 O OE1 . GLU   B 1 47  ? 8.33447   9.60966   -41.09397 1.000 78.97055 ?  47  GLU   B OE1 1 
ATOM   2673 O OE2 . GLU   B 1 47  ? 7.28856   11.40793  -40.39768 1.000 88.37267 -1 47  GLU   B OE2 1 
ATOM   2674 N N   . ASP   B 1 48  ? 9.20506   6.97171   -36.81439 1.000 53.73923 ?  48  ASP   B N   1 
ATOM   2675 C CA  . ASP   B 1 48  ? 8.20157   6.25019   -36.03476 1.000 51.99597 ?  48  ASP   B CA  1 
ATOM   2676 C C   . ASP   B 1 48  ? 8.53079   6.25159   -34.54554 1.000 49.49665 ?  48  ASP   B C   1 
ATOM   2677 O O   . ASP   B 1 48  ? 7.62054   6.29436   -33.71202 1.000 45.45353 ?  48  ASP   B O   1 
ATOM   2678 C CB  . ASP   B 1 48  ? 8.07768   4.81029   -36.52558 1.000 47.03594 ?  48  ASP   B CB  1 
ATOM   2679 C CG  . ASP   B 1 48  ? 7.59108   4.71561   -37.95545 1.000 49.84225 ?  48  ASP   B CG  1 
ATOM   2680 O OD1 . ASP   B 1 48  ? 6.90849   5.66044   -38.41258 1.000 53.00126 ?  48  ASP   B OD1 1 
ATOM   2681 O OD2 . ASP   B 1 48  ? 7.88712   3.69521   -38.61562 1.000 44.99430 -1 48  ASP   B OD2 1 
ATOM   2682 N N   . MET   B 1 49  ? 9.81931   6.20238   -34.19206 1.000 52.25687 ?  49  MET   B N   1 
ATOM   2683 C CA  . MET   B 1 49  ? 10.20258  6.08972   -32.78801 1.000 48.12846 ?  49  MET   B CA  1 
ATOM   2684 C C   . MET   B 1 49  ? 9.77994   7.29611   -31.95920 1.000 43.89700 ?  49  MET   B C   1 
ATOM   2685 O O   . MET   B 1 49  ? 9.70976   7.18560   -30.73478 1.000 43.44610 ?  49  MET   B O   1 
ATOM   2686 C CB  . MET   B 1 49  ? 11.71344  5.86810   -32.66745 1.000 46.64883 ?  49  MET   B CB  1 
ATOM   2687 C CG  . MET   B 1 49  ? 12.12808  4.41571   -32.86586 1.000 49.25811 ?  49  MET   B CG  1 
ATOM   2688 S SD  . MET   B 1 49  ? 13.90661  4.06169   -32.95703 1.000 52.85259 ?  49  MET   B SD  1 
ATOM   2689 C CE  . MET   B 1 49  ? 13.89196  2.41965   -33.67694 1.000 43.84085 ?  49  MET   B CE  1 
ATOM   2690 N N   . LEU   B 1 50  ? 9.47083   8.43563   -32.58157 1.000 47.53489 ?  50  LEU   B N   1 
ATOM   2691 C CA  . LEU   B 1 50  ? 9.15145   9.62372   -31.79219 1.000 45.93802 ?  50  LEU   B CA  1 
ATOM   2692 C C   . LEU   B 1 50  ? 7.82233   9.47769   -31.05368 1.000 47.97750 ?  50  LEU   B C   1 
ATOM   2693 O O   . LEU   B 1 50  ? 7.70528   9.89685   -29.89497 1.000 47.99925 ?  50  LEU   B O   1 
ATOM   2694 C CB  . LEU   B 1 50  ? 9.14488   10.86501  -32.68444 1.000 51.96580 ?  50  LEU   B CB  1 
ATOM   2695 C CG  . LEU   B 1 50  ? 10.51554  11.19489  -33.27924 1.000 54.25891 ?  50  LEU   B CG  1 
ATOM   2696 C CD1 . LEU   B 1 50  ? 10.52253  12.56480  -33.94784 1.000 53.85606 ?  50  LEU   B CD1 1 
ATOM   2697 C CD2 . LEU   B 1 50  ? 11.60627  11.10146  -32.20995 1.000 48.30223 ?  50  LEU   B CD2 1 
ATOM   2698 N N   . ASN   B 1 51  ? 6.80929   8.90297   -31.70247 1.000 49.07630 ?  51  ASN   B N   1 
ATOM   2699 C CA  . ASN   B 1 51  ? 5.52972   8.60793   -31.04981 1.000 48.09409 ?  51  ASN   B CA  1 
ATOM   2700 C C   . ASN   B 1 51  ? 4.86716   7.43053   -31.74979 1.000 46.87929 ?  51  ASN   B C   1 
ATOM   2701 O O   . ASN   B 1 51  ? 3.88425   7.58748   -32.48624 1.000 45.83078 ?  51  ASN   B O   1 
ATOM   2702 C CB  . ASN   B 1 51  ? 4.60327   9.82359   -31.04613 1.000 49.21390 ?  51  ASN   B CB  1 
ATOM   2703 C CG  . ASN   B 1 51  ? 3.53364   9.71887   -29.97957 1.000 53.37445 ?  51  ASN   B CG  1 
ATOM   2704 O OD1 . ASN   B 1 51  ? 3.39417   8.67762   -29.33390 1.000 49.54911 ?  51  ASN   B OD1 1 
ATOM   2705 N ND2 . ASN   B 1 51  ? 2.77665   10.79431  -29.78155 1.000 57.48129 ?  51  ASN   B ND2 1 
ATOM   2706 N N   . PRO   B 1 52  ? 5.36551   6.21895   -31.51412 1.000 41.97173 ?  52  PRO   B N   1 
ATOM   2707 C CA  . PRO   B 1 52  ? 4.92542   5.05947   -32.30052 1.000 40.14368 ?  52  PRO   B CA  1 
ATOM   2708 C C   . PRO   B 1 52  ? 3.59339   4.48125   -31.84663 1.000 42.36195 ?  52  PRO   B C   1 
ATOM   2709 O O   . PRO   B 1 52  ? 3.33871   4.29993   -30.65204 1.000 40.88120 ?  52  PRO   B O   1 
ATOM   2710 C CB  . PRO   B 1 52  ? 6.05039   4.04514   -32.07118 1.000 38.32882 ?  52  PRO   B CB  1 
ATOM   2711 C CG  . PRO   B 1 52  ? 6.54928   4.39213   -30.69355 1.000 40.12022 ?  52  PRO   B CG  1 
ATOM   2712 C CD  . PRO   B 1 52  ? 6.42416   5.87344   -30.54735 1.000 41.62169 ?  52  PRO   B CD  1 
ATOM   2713 N N   . ASN   B 1 53  ? 2.75156   4.14817   -32.82942 1.000 40.59566 ?  53  ASN   B N   1 
ATOM   2714 C CA  . ASN   B 1 53  ? 1.56743   3.32254   -32.60789 1.000 37.84397 ?  53  ASN   B CA  1 
ATOM   2715 C C   . ASN   B 1 53  ? 1.96762   1.91574   -33.02748 1.000 41.57840 ?  53  ASN   B C   1 
ATOM   2716 O O   . ASN   B 1 53  ? 1.89738   1.56033   -34.20667 1.000 35.53169 ?  53  ASN   B O   1 
ATOM   2717 C CB  . ASN   B 1 53  ? 0.36392   3.82667   -33.40427 1.000 42.29854 ?  53  ASN   B CB  1 
ATOM   2718 C CG  . ASN   B 1 53  ? -0.93591  3.16031   -32.98986 1.000 40.39051 ?  53  ASN   B CG  1 
ATOM   2719 O OD1 . ASN   B 1 53  ? -1.00978  1.93399   -32.83553 1.000 42.26616 ?  53  ASN   B OD1 1 
ATOM   2720 N ND2 . ASN   B 1 53  ? -1.97985  3.96548   -32.82251 1.000 48.37075 ?  53  ASN   B ND2 1 
ATOM   2721 N N   . TYR   B 1 54  ? 2.41671   1.11479   -32.05895 1.000 33.28283 ?  54  TYR   B N   1 
ATOM   2722 C CA  . TYR   B 1 54  ? 3.06393   -0.13935  -32.40960 1.000 33.09577 ?  54  TYR   B CA  1 
ATOM   2723 C C   . TYR   B 1 54  ? 2.10908   -1.13901  -33.06801 1.000 32.12267 ?  54  TYR   B C   1 
ATOM   2724 O O   . TYR   B 1 54  ? 2.52300   -1.86833  -33.96693 1.000 33.29136 ?  54  TYR   B O   1 
ATOM   2725 C CB  . TYR   B 1 54  ? 3.72424   -0.73949  -31.16643 1.000 30.27906 ?  54  TYR   B CB  1 
ATOM   2726 C CG  . TYR   B 1 54  ? 5.04072   -0.09778  -30.80932 1.000 32.51206 ?  54  TYR   B CG  1 
ATOM   2727 C CD1 . TYR   B 1 54  ? 6.17922   -0.35647  -31.55996 1.000 32.01629 ?  54  TYR   B CD1 1 
ATOM   2728 C CD2 . TYR   B 1 54  ? 5.16229   0.74020   -29.68945 1.000 28.46931 ?  54  TYR   B CD2 1 
ATOM   2729 C CE1 . TYR   B 1 54  ? 7.39316   0.20229   -31.20942 1.000 33.69367 ?  54  TYR   B CE1 1 
ATOM   2730 C CE2 . TYR   B 1 54  ? 6.38000   1.30179   -29.34593 1.000 29.41135 ?  54  TYR   B CE2 1 
ATOM   2731 C CZ  . TYR   B 1 54  ? 7.48689   1.02076   -30.11269 1.000 31.93362 ?  54  TYR   B CZ  1 
ATOM   2732 O OH  . TYR   B 1 54  ? 8.70305   1.56545   -29.79617 1.000 30.12064 ?  54  TYR   B OH  1 
ATOM   2733 N N   . GLU   B 1 55  ? 0.84304   -1.20971  -32.64408 1.000 35.16432 ?  55  GLU   B N   1 
ATOM   2734 C CA  . GLU   B 1 55  ? -0.07931  -2.15084  -33.28868 1.000 39.53788 ?  55  GLU   B CA  1 
ATOM   2735 C C   . GLU   B 1 55  ? -0.24798  -1.81949  -34.77002 1.000 39.20645 ?  55  GLU   B C   1 
ATOM   2736 O O   . GLU   B 1 55  ? -0.22040  -2.71131  -35.62868 1.000 38.62760 ?  55  GLU   B O   1 
ATOM   2737 C CB  . GLU   B 1 55  ? -1.44821  -2.14305  -32.60096 1.000 41.32581 ?  55  GLU   B CB  1 
ATOM   2738 C CG  . GLU   B 1 55  ? -1.49554  -2.78631  -31.22013 1.000 46.24812 ?  55  GLU   B CG  1 
ATOM   2739 C CD  . GLU   B 1 55  ? -1.13733  -4.26987  -31.21129 1.000 50.89587 ?  55  GLU   B CD  1 
ATOM   2740 O OE1 . GLU   B 1 55  ? -0.89326  -4.87200  -32.28677 1.000 53.38061 ?  55  GLU   B OE1 1 
ATOM   2741 O OE2 . GLU   B 1 55  ? -1.08725  -4.84554  -30.10265 1.000 51.42429 -1 55  GLU   B OE2 1 
ATOM   2742 N N   . ASP   B 1 56  ? -0.41390  -0.52921  -35.07446 1.000 39.75628 ?  56  ASP   B N   1 
ATOM   2743 C CA  . ASP   B 1 56  ? -0.50475  -0.06047  -36.45798 1.000 39.22260 ?  56  ASP   B CA  1 
ATOM   2744 C C   . ASP   B 1 56  ? 0.72489   -0.45045  -37.25802 1.000 43.17328 ?  56  ASP   B C   1 
ATOM   2745 O O   . ASP   B 1 56  ? 0.62147   -1.04578  -38.33667 1.000 41.01404 ?  56  ASP   B O   1 
ATOM   2746 C CB  . ASP   B 1 56  ? -0.65225  1.45601   -36.47401 1.000 44.42830 ?  56  ASP   B CB  1 
ATOM   2747 C CG  . ASP   B 1 56  ? -2.07884  1.90159   -36.42933 1.000 48.41060 ?  56  ASP   B CG  1 
ATOM   2748 O OD1 . ASP   B 1 56  ? -2.88759  1.29997   -35.68835 1.000 49.45321 ?  56  ASP   B OD1 1 
ATOM   2749 O OD2 . ASP   B 1 56  ? -2.38056  2.87211   -37.14465 1.000 53.02798 -1 56  ASP   B OD2 1 
ATOM   2750 N N   . LEU   B 1 57  ? 1.90556   -0.07717  -36.75708 1.000 38.57424 ?  57  LEU   B N   1 
ATOM   2751 C CA  . LEU   B 1 57  ? 3.14054   -0.40393  -37.45220 1.000 35.35051 ?  57  LEU   B CA  1 
ATOM   2752 C C   . LEU   B 1 57  ? 3.25045   -1.89633  -37.68192 1.000 34.19423 ?  57  LEU   B C   1 
ATOM   2753 O O   . LEU   B 1 57  ? 3.73900   -2.33995  -38.72767 1.000 37.48038 ?  57  LEU   B O   1 
ATOM   2754 C CB  . LEU   B 1 57  ? 4.34060   0.10255   -36.63889 1.000 33.13929 ?  57  LEU   B CB  1 
ATOM   2755 C CG  . LEU   B 1 57  ? 4.43612   1.60945   -36.42572 1.000 32.79368 ?  57  LEU   B CG  1 
ATOM   2756 C CD1 . LEU   B 1 57  ? 5.59866   1.93648   -35.46038 1.000 38.77424 ?  57  LEU   B CD1 1 
ATOM   2757 C CD2 . LEU   B 1 57  ? 4.60073   2.35369   -37.75288 1.000 44.31860 ?  57  LEU   B CD2 1 
ATOM   2758 N N   . LEU   B 1 58  ? 2.81948   -2.69692  -36.70625 1.000 33.47902 ?  58  LEU   B N   1 
ATOM   2759 C CA  . LEU   B 1 58  ? 3.04428   -4.12750  -36.81988 1.000 35.66355 ?  58  LEU   B CA  1 
ATOM   2760 C C   . LEU   B 1 58  ? 2.12000   -4.74617  -37.85256 1.000 35.33242 ?  58  LEU   B C   1 
ATOM   2761 O O   . LEU   B 1 58  ? 2.54747   -5.61226  -38.62049 1.000 35.10673 ?  58  LEU   B O   1 
ATOM   2762 C CB  . LEU   B 1 58  ? 2.87116   -4.81741  -35.47260 1.000 35.53553 ?  58  LEU   B CB  1 
ATOM   2763 C CG  . LEU   B 1 58  ? 3.13450   -6.31912  -35.52681 1.000 38.51726 ?  58  LEU   B CG  1 
ATOM   2764 C CD1 . LEU   B 1 58  ? 4.48556   -6.61456  -36.17787 1.000 42.16892 ?  58  LEU   B CD1 1 
ATOM   2765 C CD2 . LEU   B 1 58  ? 3.07971   -6.91276  -34.13271 1.000 39.71145 ?  58  LEU   B CD2 1 
ATOM   2766 N N   . ILE   B 1 59  ? 0.85364   -4.31683  -37.89043 1.000 37.74054 ?  59  ILE   B N   1 
ATOM   2767 C CA  . ILE   B 1 59  ? -0.06580  -4.91420  -38.85862 1.000 33.95087 ?  59  ILE   B CA  1 
ATOM   2768 C C   . ILE   B 1 59  ? 0.35673   -4.58846  -40.28734 1.000 38.53236 ?  59  ILE   B C   1 
ATOM   2769 O O   . ILE   B 1 59  ? 0.00900   -5.31990  -41.21914 1.000 40.69420 ?  59  ILE   B O   1 
ATOM   2770 C CB  . ILE   B 1 59  ? -1.52700  -4.48597  -38.58358 1.000 35.85020 ?  59  ILE   B CB  1 
ATOM   2771 C CG1 . ILE   B 1 59  ? -2.48811  -5.24073  -39.51279 1.000 40.38500 ?  59  ILE   B CG1 1 
ATOM   2772 C CG2 . ILE   B 1 59  ? -1.71472  -3.00704  -38.81474 1.000 38.68756 ?  59  ILE   B CG2 1 
ATOM   2773 C CD1 . ILE   B 1 59  ? -3.79357  -5.68349  -38.85758 1.000 44.32940 ?  59  ILE   B CD1 1 
ATOM   2774 N N   . ARG   B 1 60  ? 1.12958   -3.52545  -40.48765 1.000 36.33083 ?  60  ARG   B N   1 
ATOM   2775 C CA  . ARG   B 1 60  ? 1.59029   -3.17962  -41.82904 1.000 38.34686 ?  60  ARG   B CA  1 
ATOM   2776 C C   . ARG   B 1 60  ? 2.84304   -3.93572  -42.24071 1.000 39.37483 ?  60  ARG   B C   1 
ATOM   2777 O O   . ARG   B 1 60  ? 3.30928   -3.76595  -43.37096 1.000 41.37900 ?  60  ARG   B O   1 
ATOM   2778 C CB  . ARG   B 1 60  ? 1.80806   -1.67239  -41.91167 1.000 33.24362 ?  60  ARG   B CB  1 
ATOM   2779 C CG  . ARG   B 1 60  ? 0.52071   -0.96306  -41.60029 1.000 35.76479 ?  60  ARG   B CG  1 
ATOM   2780 C CD  . ARG   B 1 60  ? 0.62744   0.52652   -41.41018 1.000 39.44101 ?  60  ARG   B CD  1 
ATOM   2781 N NE  . ARG   B 1 60  ? -0.70071  1.05835   -41.13498 1.000 42.38868 ?  60  ARG   B NE  1 
ATOM   2782 C CZ  . ARG   B 1 60  ? -0.94152  2.24183   -40.59378 1.000 44.40657 ?  60  ARG   B CZ  1 
ATOM   2783 N NH1 . ARG   B 1 60  ? 0.04442   3.04660   -40.22359 1.000 44.82250 ?  60  ARG   B NH1 1 
ATOM   2784 N NH2 . ARG   B 1 60  ? -2.20258  2.62555   -40.41267 1.000 42.55599 ?  60  ARG   B NH2 1 
ATOM   2785 N N   . LYS   B 1 61  ? 3.40037   -4.74992  -41.35476 1.000 36.16276 ?  61  LYS   B N   1 
ATOM   2786 C CA  . LYS   B 1 61  ? 4.58201   -5.54088  -41.63956 1.000 37.24015 ?  61  LYS   B CA  1 
ATOM   2787 C C   . LYS   B 1 61  ? 4.17720   -6.94149  -42.05819 1.000 36.49272 ?  61  LYS   B C   1 
ATOM   2788 O O   . LYS   B 1 61  ? 3.16326   -7.47673  -41.60310 1.000 39.83357 ?  61  LYS   B O   1 
ATOM   2789 C CB  . LYS   B 1 61  ? 5.50051   -5.61750  -40.40935 1.000 36.72483 ?  61  LYS   B CB  1 
ATOM   2790 C CG  . LYS   B 1 61  ? 6.14254   -4.30309  -40.05816 1.000 40.55453 ?  61  LYS   B CG  1 
ATOM   2791 C CD  . LYS   B 1 61  ? 7.40543   -4.10831  -40.86681 1.000 46.25626 ?  61  LYS   B CD  1 
ATOM   2792 C CE  . LYS   B 1 61  ? 7.67363   -2.64159  -41.10454 1.000 46.99065 ?  61  LYS   B CE  1 
ATOM   2793 N NZ  . LYS   B 1 61  ? 7.61374   -1.88235  -39.83192 1.000 48.56797 ?  61  LYS   B NZ  1 
ATOM   2794 N N   . SER   B 1 62  ? 4.97559   -7.52507  -42.94349 1.000 39.70807 ?  62  SER   B N   1 
ATOM   2795 C CA  . SER   B 1 62  ? 4.89751   -8.94220  -43.25285 1.000 40.71347 ?  62  SER   B CA  1 
ATOM   2796 C C   . SER   B 1 62  ? 6.15281   -9.64127  -42.75652 1.000 45.32293 ?  62  SER   B C   1 
ATOM   2797 O O   . SER   B 1 62  ? 7.17056   -9.00207  -42.46799 1.000 44.06394 ?  62  SER   B O   1 
ATOM   2798 C CB  . SER   B 1 62  ? 4.73682   -9.18789  -44.75755 1.000 47.52710 ?  62  SER   B CB  1 
ATOM   2799 O OG  . SER   B 1 62  ? 5.00456   -10.55107 -45.04537 1.000 51.67944 ?  62  SER   B OG  1 
ATOM   2800 N N   . ASN   B 1 63  ? 6.06380   -10.97508 -42.69145 1.000 40.40585 ?  63  ASN   B N   1 
ATOM   2801 C CA  . ASN   B 1 63  ? 7.19643   -11.80101 -42.28006 1.000 42.21752 ?  63  ASN   B CA  1 
ATOM   2802 C C   . ASN   B 1 63  ? 8.47619   -11.46063 -43.03334 1.000 46.06164 ?  63  ASN   B C   1 
ATOM   2803 O O   . ASN   B 1 63  ? 9.57060   -11.50548 -42.45672 1.000 43.01712 ?  63  ASN   B O   1 
ATOM   2804 C CB  . ASN   B 1 63  ? 6.86975   -13.28211 -42.47337 1.000 41.31125 ?  63  ASN   B CB  1 
ATOM   2805 C CG  . ASN   B 1 63  ? 5.86095   -13.78764 -41.47184 1.000 45.73968 ?  63  ASN   B CG  1 
ATOM   2806 O OD1 . ASN   B 1 63  ? 5.63436   -13.15723 -40.43580 1.000 45.10658 ?  63  ASN   B OD1 1 
ATOM   2807 N ND2 . ASN   B 1 63  ? 5.25622   -14.93506 -41.76172 1.000 42.53228 ?  63  ASN   B ND2 1 
ATOM   2808 N N   . HIS   B 1 64  ? 8.37380   -11.15297 -44.32977 1.000 44.12836 ?  64  HIS   B N   1 
ATOM   2809 C CA  . HIS   B 1 64  ? 9.60212   -10.96380 -45.08738 1.000 43.36570 ?  64  HIS   B CA  1 
ATOM   2810 C C   . HIS   B 1 64  ? 10.27025  -9.63097  -44.78577 1.000 44.65944 ?  64  HIS   B C   1 
ATOM   2811 O O   . HIS   B 1 64  ? 11.41914  -9.42914  -45.19309 1.000 45.75658 ?  64  HIS   B O   1 
ATOM   2812 C CB  . HIS   B 1 64  ? 9.33817   -11.11566 -46.59445 1.000 48.05858 ?  64  HIS   B CB  1 
ATOM   2813 C CG  . HIS   B 1 64  ? 8.71027   -9.91725  -47.23144 1.000 47.78431 ?  64  HIS   B CG  1 
ATOM   2814 N ND1 . HIS   B 1 64  ? 7.36063   -9.83428  -47.49753 1.000 52.41498 ?  64  HIS   B ND1 1 
ATOM   2815 C CD2 . HIS   B 1 64  ? 9.25163   -8.75636  -47.67099 1.000 50.80145 ?  64  HIS   B CD2 1 
ATOM   2816 C CE1 . HIS   B 1 64  ? 7.09551   -8.67052  -48.06558 1.000 50.32663 ?  64  HIS   B CE1 1 
ATOM   2817 N NE2 . HIS   B 1 64  ? 8.22537   -7.99609  -48.17910 1.000 54.35708 ?  64  HIS   B NE2 1 
ATOM   2818 N N   . ASN   B 1 65  ? 9.60207   -8.72861  -44.06435 1.000 41.94666 ?  65  ASN   B N   1 
ATOM   2819 C CA  . ASN   B 1 65  ? 10.26313  -7.49940  -43.65179 1.000 40.88198 ?  65  ASN   B CA  1 
ATOM   2820 C C   . ASN   B 1 65  ? 11.30095  -7.73559  -42.56114 1.000 37.44659 ?  65  ASN   B C   1 
ATOM   2821 O O   . ASN   B 1 65  ? 12.05334  -6.81389  -42.24569 1.000 41.26390 ?  65  ASN   B O   1 
ATOM   2822 C CB  . ASN   B 1 65  ? 9.24474   -6.47696  -43.15162 1.000 39.11645 ?  65  ASN   B CB  1 
ATOM   2823 C CG  . ASN   B 1 65  ? 8.27895   -6.03961  -44.23349 1.000 46.36852 ?  65  ASN   B CG  1 
ATOM   2824 O OD1 . ASN   B 1 65  ? 7.06022   -6.07182  -44.04626 1.000 46.72776 ?  65  ASN   B OD1 1 
ATOM   2825 N ND2 . ASN   B 1 65  ? 8.81975   -5.64675  -45.38083 1.000 45.57883 ?  65  ASN   B ND2 1 
ATOM   2826 N N   . PHE   B 1 66  ? 11.34804  -8.92460  -41.98029 1.000 38.98790 ?  66  PHE   B N   1 
ATOM   2827 C CA  . PHE   B 1 66  ? 12.24274  -9.22176  -40.86368 1.000 38.12187 ?  66  PHE   B CA  1 
ATOM   2828 C C   . PHE   B 1 66  ? 13.38738  -10.10470 -41.33180 1.000 38.72940 ?  66  PHE   B C   1 
ATOM   2829 O O   . PHE   B 1 66  ? 13.16105  -11.22394 -41.80405 1.000 42.92371 ?  66  PHE   B O   1 
ATOM   2830 C CB  . PHE   B 1 66  ? 11.48932  -9.90567  -39.73008 1.000 35.24255 ?  66  PHE   B CB  1 
ATOM   2831 C CG  . PHE   B 1 66  ? 10.43144  -9.05699  -39.13229 1.000 39.37360 ?  66  PHE   B CG  1 
ATOM   2832 C CD1 . PHE   B 1 66  ? 10.76068  -8.04053  -38.24637 1.000 42.97485 ?  66  PHE   B CD1 1 
ATOM   2833 C CD2 . PHE   B 1 66  ? 9.10406   -9.25243  -39.46371 1.000 38.14290 ?  66  PHE   B CD2 1 
ATOM   2834 C CE1 . PHE   B 1 66  ? 9.78574   -7.23955  -37.69894 1.000 39.70347 ?  66  PHE   B CE1 1 
ATOM   2835 C CE2 . PHE   B 1 66  ? 8.11843   -8.45508  -38.91944 1.000 42.62842 ?  66  PHE   B CE2 1 
ATOM   2836 C CZ  . PHE   B 1 66  ? 8.45866   -7.44663  -38.03516 1.000 41.03741 ?  66  PHE   B CZ  1 
ATOM   2837 N N   . LEU   B 1 67  ? 14.61012  -9.61770  -41.16415 1.000 36.49935 ?  67  LEU   B N   1 
ATOM   2838 C CA  . LEU   B 1 67  ? 15.81068  -10.35288 -41.52852 1.000 37.22139 ?  67  LEU   B CA  1 
ATOM   2839 C C   . LEU   B 1 67  ? 16.47549  -10.76288 -40.22597 1.000 36.21464 ?  67  LEU   B C   1 
ATOM   2840 O O   . LEU   B 1 67  ? 16.92052  -9.90063  -39.46575 1.000 36.32844 ?  67  LEU   B O   1 
ATOM   2841 C CB  . LEU   B 1 67  ? 16.73986  -9.49015  -42.37775 1.000 41.31255 ?  67  LEU   B CB  1 
ATOM   2842 C CG  . LEU   B 1 67  ? 18.14576  -10.05569 -42.58354 1.000 46.39171 ?  67  LEU   B CG  1 
ATOM   2843 C CD1 . LEU   B 1 67  ? 18.08048  -11.41351 -43.27589 1.000 46.02070 ?  67  LEU   B CD1 1 
ATOM   2844 C CD2 . LEU   B 1 67  ? 19.01968  -9.07721  -43.35776 1.000 45.96036 ?  67  LEU   B CD2 1 
ATOM   2845 N N   . VAL   B 1 68  ? 16.50342  -12.06105 -39.96305 1.000 37.48812 ?  68  VAL   B N   1 
ATOM   2846 C CA  . VAL   B 1 68  ? 17.13432  -12.63750 -38.77752 1.000 36.85298 ?  68  VAL   B CA  1 
ATOM   2847 C C   . VAL   B 1 68  ? 18.38392  -13.38648 -39.22320 1.000 42.66580 ?  68  VAL   B C   1 
ATOM   2848 O O   . VAL   B 1 68  ? 18.31270  -14.26972 -40.08614 1.000 41.29156 ?  68  VAL   B O   1 
ATOM   2849 C CB  . VAL   B 1 68  ? 16.17244  -13.58063 -38.04156 1.000 36.01858 ?  68  VAL   B CB  1 
ATOM   2850 C CG1 . VAL   B 1 68  ? 16.87454  -14.26605 -36.85251 1.000 33.17586 ?  68  VAL   B CG1 1 
ATOM   2851 C CG2 . VAL   B 1 68  ? 14.93007  -12.81770 -37.59734 1.000 34.91126 ?  68  VAL   B CG2 1 
ATOM   2852 N N   . GLN   B 1 69  ? 19.52026  -13.06965 -38.61473 1.000 40.15473 ?  69  GLN   B N   1 
ATOM   2853 C CA  . GLN   B 1 69  ? 20.77858  -13.72854 -38.94079 1.000 39.15531 ?  69  GLN   B CA  1 
ATOM   2854 C C   . GLN   B 1 69  ? 21.39975  -14.33009 -37.69043 1.000 42.13740 ?  69  GLN   B C   1 
ATOM   2855 O O   . GLN   B 1 69  ? 21.63508  -13.62016 -36.70540 1.000 38.15523 ?  69  GLN   B O   1 
ATOM   2856 C CB  . GLN   B 1 69  ? 21.75619  -12.74984 -39.58366 1.000 40.75206 ?  69  GLN   B CB  1 
ATOM   2857 C CG  . GLN   B 1 69  ? 21.26121  -12.14799 -40.88532 1.000 48.18929 ?  69  GLN   B CG  1 
ATOM   2858 C CD  . GLN   B 1 69  ? 22.08337  -10.94969 -41.30353 1.000 51.66470 ?  69  GLN   B CD  1 
ATOM   2859 O OE1 . GLN   B 1 69  ? 21.58179  -9.82404  -41.35255 1.000 52.41295 ?  69  GLN   B OE1 1 
ATOM   2860 N NE2 . GLN   B 1 69  ? 23.36486  -11.18018 -41.59223 1.000 54.06279 ?  69  GLN   B NE2 1 
ATOM   2861 N N   . ALA   B 1 70  ? 21.66800  -15.62958 -37.74270 1.000 40.62951 ?  70  ALA   B N   1 
ATOM   2862 C CA  . ALA   B 1 70  ? 22.41670  -16.36593 -36.73123 1.000 44.91003 ?  70  ALA   B CA  1 
ATOM   2863 C C   . ALA   B 1 70  ? 23.79277  -16.65502 -37.33056 1.000 47.99387 ?  70  ALA   B C   1 
ATOM   2864 O O   . ALA   B 1 70  ? 23.93528  -17.52371 -38.19661 1.000 48.61675 ?  70  ALA   B O   1 
ATOM   2865 C CB  . ALA   B 1 70  ? 21.67945  -17.64665 -36.33914 1.000 41.81511 ?  70  ALA   B CB  1 
ATOM   2866 N N   . GLY   B 1 71  ? 24.80261  -15.91873 -36.88225 1.000 46.42765 ?  71  GLY   B N   1 
ATOM   2867 C CA  . GLY   B 1 71  ? 26.10004  -16.03677 -37.52476 1.000 50.32039 ?  71  GLY   B CA  1 
ATOM   2868 C C   . GLY   B 1 71  ? 25.98754  -15.70814 -39.00325 1.000 57.94978 ?  71  GLY   B C   1 
ATOM   2869 O O   . GLY   B 1 71  ? 25.45951  -14.65987 -39.39461 1.000 56.15668 ?  71  GLY   B O   1 
ATOM   2870 N N   . ASN   B 1 72  ? 26.47059  -16.62111 -39.84738 1.000 59.63714 ?  72  ASN   B N   1 
ATOM   2871 C CA  . ASN   B 1 72  ? 26.42199  -16.43588 -41.29086 1.000 61.03203 ?  72  ASN   B CA  1 
ATOM   2872 C C   . ASN   B 1 72  ? 25.19568  -17.08400 -41.92895 1.000 60.37717 ?  72  ASN   B C   1 
ATOM   2873 O O   . ASN   B 1 72  ? 25.17082  -17.26246 -43.15155 1.000 62.83877 ?  72  ASN   B O   1 
ATOM   2874 C CB  . ASN   B 1 72  ? 27.70031  -16.97937 -41.94213 1.000 64.54671 ?  72  ASN   B CB  1 
ATOM   2875 C CG  . ASN   B 1 72  ? 27.65792  -18.48540 -42.15643 1.000 68.25417 ?  72  ASN   B CG  1 
ATOM   2876 O OD1 . ASN   B 1 72  ? 27.28826  -19.24309 -41.25999 1.000 68.40527 ?  72  ASN   B OD1 1 
ATOM   2877 N ND2 . ASN   B 1 72  ? 28.02422  -18.92376 -43.35825 1.000 72.13561 ?  72  ASN   B ND2 1 
ATOM   2878 N N   . VAL   B 1 73  ? 24.17694  -17.42753 -41.14035 1.000 57.12197 ?  73  VAL   B N   1 
ATOM   2879 C CA  . VAL   B 1 73  ? 23.00658  -18.14463 -41.63457 1.000 51.17067 ?  73  VAL   B CA  1 
ATOM   2880 C C   . VAL   B 1 73  ? 21.76515  -17.28966 -41.42442 1.000 50.31972 ?  73  VAL   B C   1 
ATOM   2881 O O   . VAL   B 1 73  ? 21.48892  -16.85367 -40.30403 1.000 49.37628 ?  73  VAL   B O   1 
ATOM   2882 C CB  . VAL   B 1 73  ? 22.84454  -19.50526 -40.93463 1.000 55.30809 ?  73  VAL   B CB  1 
ATOM   2883 C CG1 . VAL   B 1 73  ? 21.46787  -20.07578 -41.20243 1.000 53.00897 ?  73  VAL   B CG1 1 
ATOM   2884 C CG2 . VAL   B 1 73  ? 23.92581  -20.46645 -41.39556 1.000 57.49907 ?  73  VAL   B CG2 1 
ATOM   2885 N N   . GLN   B 1 74  ? 20.99678  -17.08124 -42.48742 1.000 48.99928 ?  74  GLN   B N   1 
ATOM   2886 C CA  . GLN   B 1 74  ? 19.73217  -16.37237 -42.37213 1.000 45.61372 ?  74  GLN   B CA  1 
ATOM   2887 C C   . GLN   B 1 74  ? 18.64132  -17.35391 -41.96981 1.000 46.59415 ?  74  GLN   B C   1 
ATOM   2888 O O   . GLN   B 1 74  ? 18.50975  -18.42602 -42.56617 1.000 50.72616 ?  74  GLN   B O   1 
ATOM   2889 C CB  . GLN   B 1 74  ? 19.38035  -15.66730 -43.68017 1.000 46.26092 ?  74  GLN   B CB  1 
ATOM   2890 C CG  . GLN   B 1 74  ? 20.33605  -14.54048 -44.02101 1.000 55.50303 ?  74  GLN   B CG  1 
ATOM   2891 C CD  . GLN   B 1 74  ? 19.87328  -13.70641 -45.20240 1.000 66.69293 ?  74  GLN   B CD  1 
ATOM   2892 O OE1 . GLN   B 1 74  ? 18.81808  -13.96611 -45.79183 1.000 69.39511 ?  74  GLN   B OE1 1 
ATOM   2893 N NE2 . GLN   B 1 74  ? 20.66293  -12.69298 -45.55456 1.000 65.74693 ?  74  GLN   B NE2 1 
ATOM   2894 N N   . LEU   B 1 75  ? 17.87779  -16.99332 -40.94424 1.000 44.01067 ?  75  LEU   B N   1 
ATOM   2895 C CA  . LEU   B 1 75  ? 16.74430  -17.78174 -40.48667 1.000 44.54682 ?  75  LEU   B CA  1 
ATOM   2896 C C   . LEU   B 1 75  ? 15.47111  -17.23371 -41.12246 1.000 43.37518 ?  75  LEU   B C   1 
ATOM   2897 O O   . LEU   B 1 75  ? 15.24906  -16.01738 -41.13650 1.000 43.93827 ?  75  LEU   B O   1 
ATOM   2898 C CB  . LEU   B 1 75  ? 16.63574  -17.74556 -38.96007 1.000 44.28164 ?  75  LEU   B CB  1 
ATOM   2899 C CG  . LEU   B 1 75  ? 17.86514  -18.19351 -38.16825 1.000 42.86448 ?  75  LEU   B CG  1 
ATOM   2900 C CD1 . LEU   B 1 75  ? 17.59914  -18.08767 -36.66550 1.000 35.99609 ?  75  LEU   B CD1 1 
ATOM   2901 C CD2 . LEU   B 1 75  ? 18.28001  -19.61599 -38.54679 1.000 45.52277 ?  75  LEU   B CD2 1 
ATOM   2902 N N   . ARG   B 1 76  ? 14.63710  -18.12592 -41.64821 1.000 47.30616 ?  76  ARG   B N   1 
ATOM   2903 C CA  . ARG   B 1 76  ? 13.41689  -17.69410 -42.31975 1.000 44.59258 ?  76  ARG   B CA  1 
ATOM   2904 C C   . ARG   B 1 76  ? 12.30717  -17.48477 -41.29533 1.000 36.66682 ?  76  ARG   B C   1 
ATOM   2905 O O   . ARG   B 1 76  ? 11.97033  -18.40357 -40.54427 1.000 38.72949 ?  76  ARG   B O   1 
ATOM   2906 C CB  . ARG   B 1 76  ? 12.99781  -18.72170 -43.36850 1.000 45.70937 ?  76  ARG   B CB  1 
ATOM   2907 C CG  . ARG   B 1 76  ? 11.78446  -18.31602 -44.18409 1.000 51.42724 ?  76  ARG   B CG  1 
ATOM   2908 C CD  . ARG   B 1 76  ? 11.46570  -19.36639 -45.24720 1.000 52.28498 ?  76  ARG   B CD  1 
ATOM   2909 N NE  . ARG   B 1 76  ? 11.29223  -20.68917 -44.65545 1.000 57.41663 ?  76  ARG   B NE  1 
ATOM   2910 C CZ  . ARG   B 1 76  ? 10.15578  -21.37479 -44.65062 1.000 60.82824 ?  76  ARG   B CZ  1 
ATOM   2911 N NH1 . ARG   B 1 76  ? 9.06406   -20.91377 -45.24735 1.000 57.13621 ?  76  ARG   B NH1 1 
ATOM   2912 N NH2 . ARG   B 1 76  ? 10.11537  -22.55723 -44.03826 1.000 58.68009 ?  76  ARG   B NH2 1 
ATOM   2913 N N   . VAL   B 1 77  ? 11.74457  -16.28014 -41.27270 1.000 38.28848 ?  77  VAL   B N   1 
ATOM   2914 C CA  . VAL   B 1 77  ? 10.65380  -15.93423 -40.36476 1.000 40.15446 ?  77  VAL   B CA  1 
ATOM   2915 C C   . VAL   B 1 77  ? 9.33179   -16.40384 -40.96447 1.000 41.45183 ?  77  VAL   B C   1 
ATOM   2916 O O   . VAL   B 1 77  ? 8.93761   -15.94804 -42.04356 1.000 42.85690 ?  77  VAL   B O   1 
ATOM   2917 C CB  . VAL   B 1 77  ? 10.61762  -14.42244 -40.10803 1.000 38.63283 ?  77  VAL   B CB  1 
ATOM   2918 C CG1 . VAL   B 1 77  ? 9.39972   -14.06514 -39.29205 1.000 41.23939 ?  77  VAL   B CG1 1 
ATOM   2919 C CG2 . VAL   B 1 77  ? 11.89574  -13.95787 -39.41063 1.000 37.59765 ?  77  VAL   B CG2 1 
ATOM   2920 N N   . ILE   B 1 78  ? 8.62051   -17.27205 -40.24180 1.000 39.45503 ?  78  ILE   B N   1 
ATOM   2921 C CA  . ILE   B 1 78  ? 7.35602   -17.82544 -40.70869 1.000 42.77519 ?  78  ILE   B CA  1 
ATOM   2922 C C   . ILE   B 1 78  ? 6.18313   -17.41273 -39.82616 1.000 45.14987 ?  78  ILE   B C   1 
ATOM   2923 O O   . ILE   B 1 78  ? 5.07636   -17.93423 -39.98757 1.000 44.25642 ?  78  ILE   B O   1 
ATOM   2924 C CB  . ILE   B 1 78  ? 7.42701   -19.35886 -40.82412 1.000 40.83798 ?  78  ILE   B CB  1 
ATOM   2925 C CG1 . ILE   B 1 78  ? 7.66013   -19.98297 -39.44519 1.000 44.49858 ?  78  ILE   B CG1 1 
ATOM   2926 C CG2 . ILE   B 1 78  ? 8.50283   -19.76469 -41.82936 1.000 41.72506 ?  78  ILE   B CG2 1 
ATOM   2927 C CD1 . ILE   B 1 78  ? 7.57268   -21.47570 -39.41582 1.000 42.73449 ?  78  ILE   B CD1 1 
ATOM   2928 N N   . GLY   B 1 79  ? 6.40707   -16.52478 -38.86532 1.000 41.17829 ?  79  GLY   B N   1 
ATOM   2929 C CA  . GLY   B 1 79  ? 5.28358   -15.96689 -38.10796 1.000 44.25603 ?  79  GLY   B CA  1 
ATOM   2930 C C   . GLY   B 1 79  ? 5.77623   -14.81231 -37.25759 1.000 40.54486 ?  79  GLY   B C   1 
ATOM   2931 O O   . GLY   B 1 79  ? 6.98002   -14.63366 -37.06768 1.000 38.48525 ?  79  GLY   B O   1 
ATOM   2932 N N   . HIS   B 1 80  ? 4.82320   -14.02581 -36.74814 1.000 38.89579 ?  80  HIS   B N   1 
ATOM   2933 C CA  . HIS   B 1 80  ? 5.22690   -12.92330 -35.87295 1.000 37.88382 ?  80  HIS   B CA  1 
ATOM   2934 C C   . HIS   B 1 80  ? 4.05880   -12.42688 -35.03465 1.000 40.40164 ?  80  HIS   B C   1 
ATOM   2935 O O   . HIS   B 1 80  ? 2.94346   -12.25266 -35.53604 1.000 37.04851 ?  80  HIS   B O   1 
ATOM   2936 C CB  . HIS   B 1 80  ? 5.81372   -11.74205 -36.65914 1.000 39.35417 ?  80  HIS   B CB  1 
ATOM   2937 C CG  . HIS   B 1 80  ? 4.81975   -11.03404 -37.52282 1.000 46.57940 ?  80  HIS   B CG  1 
ATOM   2938 N ND1 . HIS   B 1 80  ? 4.62947   -11.35451 -38.85067 1.000 43.96399 ?  80  HIS   B ND1 1 
ATOM   2939 C CD2 . HIS   B 1 80  ? 3.95448   -10.02724 -37.25118 1.000 42.68297 ?  80  HIS   B CD2 1 
ATOM   2940 C CE1 . HIS   B 1 80  ? 3.69219   -10.57623 -39.35908 1.000 41.23530 ?  80  HIS   B CE1 1 
ATOM   2941 N NE2 . HIS   B 1 80  ? 3.26317   -9.76448  -38.40954 1.000 44.66108 ?  80  HIS   B NE2 1 
ATOM   2942 N N   . SER   B 1 81  ? 4.33724   -12.15807 -33.76024 1.000 34.24596 ?  81  SER   B N   1 
ATOM   2943 C CA  . SER   B 1 81  ? 3.34418   -11.54114 -32.89675 1.000 33.71634 ?  81  SER   B CA  1 
ATOM   2944 C C   . SER   B 1 81  ? 4.03949   -10.57697 -31.94891 1.000 37.48759 ?  81  SER   B C   1 
ATOM   2945 O O   . SER   B 1 81  ? 5.26956   -10.46056 -31.93315 1.000 33.59543 ?  81  SER   B O   1 
ATOM   2946 C CB  . SER   B 1 81  ? 2.54549   -12.57597 -32.11233 1.000 35.82371 ?  81  SER   B CB  1 
ATOM   2947 O OG  . SER   B 1 81  ? 3.38327   -13.42119 -31.34393 1.000 40.19492 ?  81  SER   B OG  1 
ATOM   2948 N N   . MET   B 1 82  ? 3.22833   -9.87236  -31.16537 1.000 31.15682 ?  82  MET   B N   1 
ATOM   2949 C CA  . MET   B 1 82  ? 3.74081   -8.89861  -30.21091 1.000 32.49727 ?  82  MET   B CA  1 
ATOM   2950 C C   . MET   B 1 82  ? 3.18526   -9.20285  -28.83047 1.000 30.40770 ?  82  MET   B C   1 
ATOM   2951 O O   . MET   B 1 82  ? 1.98054   -9.43110  -28.67786 1.000 29.88048 ?  82  MET   B O   1 
ATOM   2952 C CB  . MET   B 1 82  ? 3.35283   -7.49062  -30.64446 1.000 34.42913 ?  82  MET   B CB  1 
ATOM   2953 C CG  . MET   B 1 82  ? 3.98092   -6.40393  -29.85363 1.000 31.36918 ?  82  MET   B CG  1 
ATOM   2954 S SD  . MET   B 1 82  ? 3.77268   -4.78598  -30.61630 1.000 34.62464 ?  82  MET   B SD  1 
ATOM   2955 C CE  . MET   B 1 82  ? 2.02094   -4.54755  -30.56123 1.000 41.19202 ?  82  MET   B CE  1 
ATOM   2956 N N   . GLN   B 1 83  ? 4.05635   -9.20933  -27.81777 1.000 27.10180 ?  83  GLN   B N   1 
ATOM   2957 C CA  . GLN   B 1 83  ? 3.62922   -9.37427  -26.43595 1.000 27.88169 ?  83  GLN   B CA  1 
ATOM   2958 C C   . GLN   B 1 83  ? 4.19109   -8.17510  -25.67901 1.000 27.94866 ?  83  GLN   B C   1 
ATOM   2959 O O   . GLN   B 1 83  ? 5.39651   -8.11554  -25.39985 1.000 24.01211 ?  83  GLN   B O   1 
ATOM   2960 C CB  . GLN   B 1 83  ? 4.11401   -10.69737 -25.84558 1.000 29.34693 ?  83  GLN   B CB  1 
ATOM   2961 C CG  . GLN   B 1 83  ? 3.73782   -10.86585 -24.38562 1.000 28.10795 ?  83  GLN   B CG  1 
ATOM   2962 C CD  . GLN   B 1 83  ? 4.11652   -12.21444 -23.82230 1.000 32.18423 ?  83  GLN   B CD  1 
ATOM   2963 O OE1 . GLN   B 1 83  ? 4.90975   -12.95150 -24.41373 1.000 35.87393 ?  83  GLN   B OE1 1 
ATOM   2964 N NE2 . GLN   B 1 83  ? 3.54057   -12.55592 -22.67591 1.000 33.91999 ?  83  GLN   B NE2 1 
ATOM   2965 N N   . ASN   B 1 84  ? 3.31215   -7.21734  -25.38525 1.000 28.10353 ?  84  ASN   B N   1 
ATOM   2966 C CA  . ASN   B 1 84  ? 3.71664   -5.95616  -24.78290 1.000 27.97725 ?  84  ASN   B CA  1 
ATOM   2967 C C   . ASN   B 1 84  ? 4.86229   -5.33378  -25.57147 1.000 29.27510 ?  84  ASN   B C   1 
ATOM   2968 O O   . ASN   B 1 84  ? 4.71077   -5.11394  -26.77317 1.000 26.87008 ?  84  ASN   B O   1 
ATOM   2969 C CB  . ASN   B 1 84  ? 4.04027   -6.20567  -23.31543 1.000 27.09393 ?  84  ASN   B CB  1 
ATOM   2970 C CG  . ASN   B 1 84  ? 2.84417   -6.76453  -22.59202 1.000 30.66443 ?  84  ASN   B CG  1 
ATOM   2971 O OD1 . ASN   B 1 84  ? 1.75026   -6.18180  -22.67703 1.000 30.54603 ?  84  ASN   B OD1 1 
ATOM   2972 N ND2 . ASN   B 1 84  ? 2.99271   -7.94119  -21.98619 1.000 26.31855 ?  84  ASN   B ND2 1 
ATOM   2973 N N   . CYS   B 1 85  ? 6.01653   -5.06123  -24.95452 1.000 21.93445 ?  85  CYS   B N   1 
ATOM   2974 C CA  . CYS   B 1 85  ? 7.06683   -4.38675  -25.70975 1.000 21.53281 ?  85  CYS   B CA  1 
ATOM   2975 C C   . CYS   B 1 85  ? 8.03175   -5.34159  -26.39298 1.000 20.73026 ?  85  CYS   B C   1 
ATOM   2976 O O   . CYS   B 1 85  ? 9.08840   -4.88694  -26.85442 1.000 25.95235 ?  85  CYS   B O   1 
ATOM   2977 C CB  . CYS   B 1 85  ? 7.85177   -3.41631  -24.81892 1.000 23.18334 ?  85  CYS   B CB  1 
ATOM   2978 S SG  . CYS   B 1 85  ? 6.78465   -2.17753  -24.05301 1.000 26.03789 ?  85  CYS   B SG  1 
ATOM   2979 N N   . VAL   B 1 86  ? 7.70928   -6.63120  -26.47750 1.000 22.42692 ?  86  VAL   B N   1 
ATOM   2980 C CA  . VAL   B 1 86  ? 8.58905   -7.61859  -27.10131 1.000 23.89271 ?  86  VAL   B CA  1 
ATOM   2981 C C   . VAL   B 1 86  ? 7.94250   -8.15083  -28.37787 1.000 28.09040 ?  86  VAL   B C   1 
ATOM   2982 O O   . VAL   B 1 86  ? 6.76062   -8.52021  -28.39178 1.000 29.48589 ?  86  VAL   B O   1 
ATOM   2983 C CB  . VAL   B 1 86  ? 8.93926   -8.75906  -26.13452 1.000 26.18751 ?  86  VAL   B CB  1 
ATOM   2984 C CG1 . VAL   B 1 86  ? 9.45542   -9.95619  -26.87513 1.000 30.80940 ?  86  VAL   B CG1 1 
ATOM   2985 C CG2 . VAL   B 1 86  ? 10.01472  -8.26989  -25.12632 1.000 25.04827 ?  86  VAL   B CG2 1 
ATOM   2986 N N   . LEU   B 1 87  ? 8.71632   -8.15684  -29.45147 1.000 27.66517 ?  87  LEU   B N   1 
ATOM   2987 C CA  . LEU   B 1 87  ? 8.34374   -8.81835  -30.69738 1.000 29.90869 ?  87  LEU   B CA  1 
ATOM   2988 C C   . LEU   B 1 87  ? 8.81806   -10.26489 -30.67293 1.000 33.50363 ?  87  LEU   B C   1 
ATOM   2989 O O   . LEU   B 1 87  ? 9.94667   -10.56080 -30.24041 1.000 30.41778 ?  87  LEU   B O   1 
ATOM   2990 C CB  . LEU   B 1 87  ? 8.96356   -8.05356  -31.86873 1.000 28.59334 ?  87  LEU   B CB  1 
ATOM   2991 C CG  . LEU   B 1 87  ? 8.73903   -8.48519  -33.31031 1.000 35.17664 ?  87  LEU   B CG  1 
ATOM   2992 C CD1 . LEU   B 1 87  ? 7.27888   -8.33065  -33.65689 1.000 35.91663 ?  87  LEU   B CD1 1 
ATOM   2993 C CD2 . LEU   B 1 87  ? 9.60346   -7.63268  -34.21781 1.000 33.78245 ?  87  LEU   B CD2 1 
ATOM   2994 N N   . LYS   B 1 88  ? 7.94086   -11.17047 -31.11135 1.000 28.96934 ?  88  LYS   B N   1 
ATOM   2995 C CA  . LYS   B 1 88  ? 8.23167   -12.59068 -31.21023 1.000 28.89183 ?  88  LYS   B CA  1 
ATOM   2996 C C   . LYS   B 1 88  ? 8.16529   -13.00772 -32.67085 1.000 34.66431 ?  88  LYS   B C   1 
ATOM   2997 O O   . LYS   B 1 88  ? 7.10296   -12.92723 -33.29453 1.000 33.66443 ?  88  LYS   B O   1 
ATOM   2998 C CB  . LYS   B 1 88  ? 7.25405   -13.40800 -30.36978 1.000 32.62794 ?  88  LYS   B CB  1 
ATOM   2999 C CG  . LYS   B 1 88  ? 7.28896   -13.04581 -28.88416 1.000 37.66996 ?  88  LYS   B CG  1 
ATOM   3000 C CD  . LYS   B 1 88  ? 6.53886   -14.07151 -28.03834 1.000 36.64154 ?  88  LYS   B CD  1 
ATOM   3001 C CE  . LYS   B 1 88  ? 5.05608   -13.77679 -27.95647 1.000 41.01400 ?  88  LYS   B CE  1 
ATOM   3002 N NZ  . LYS   B 1 88  ? 4.40662   -14.53797 -26.83462 1.000 39.97448 ?  88  LYS   B NZ  1 
ATOM   3003 N N   . LEU   B 1 89  ? 9.29084   -13.47340 -33.20457 1.000 36.82713 ?  89  LEU   B N   1 
ATOM   3004 C CA  . LEU   B 1 89  ? 9.39343   -13.93956 -34.58285 1.000 34.00807 ?  89  LEU   B CA  1 
ATOM   3005 C C   . LEU   B 1 89  ? 9.47066   -15.46114 -34.58733 1.000 36.32109 ?  89  LEU   B C   1 
ATOM   3006 O O   . LEU   B 1 89  ? 10.38126  -16.04758 -34.00233 1.000 32.91026 ?  89  LEU   B O   1 
ATOM   3007 C CB  . LEU   B 1 89  ? 10.61402  -13.32511 -35.26392 1.000 33.33561 ?  89  LEU   B CB  1 
ATOM   3008 C CG  . LEU   B 1 89  ? 10.62457  -11.79849 -35.25695 1.000 34.83961 ?  89  LEU   B CG  1 
ATOM   3009 C CD1 . LEU   B 1 89  ? 11.88397  -11.25341 -35.90148 1.000 35.02451 ?  89  LEU   B CD1 1 
ATOM   3010 C CD2 . LEU   B 1 89  ? 9.37204   -11.22158 -35.95438 1.000 38.32803 ?  89  LEU   B CD2 1 
ATOM   3011 N N   . LYS   B 1 90  ? 8.50659   -16.11037 -35.22571 1.000 32.24951 ?  90  LYS   B N   1 
ATOM   3012 C CA  . LYS   B 1 90  ? 8.57757   -17.55409 -35.37632 1.000 36.34946 ?  90  LYS   B CA  1 
ATOM   3013 C C   . LYS   B 1 90  ? 9.42200   -17.86233 -36.60034 1.000 36.11832 ?  90  LYS   B C   1 
ATOM   3014 O O   . LYS   B 1 90  ? 9.16148   -17.31410 -37.67784 1.000 40.40297 ?  90  LYS   B O   1 
ATOM   3015 C CB  . LYS   B 1 90  ? 7.17698   -18.14476 -35.53427 1.000 41.82472 ?  90  LYS   B CB  1 
ATOM   3016 C CG  . LYS   B 1 90  ? 7.16372   -19.65118 -35.68013 1.000 43.78396 ?  90  LYS   B CG  1 
ATOM   3017 C CD  . LYS   B 1 90  ? 5.74861   -20.18383 -35.90739 1.000 47.95689 ?  90  LYS   B CD  1 
ATOM   3018 C CE  . LYS   B 1 90  ? 5.76453   -21.70181 -35.96184 1.000 51.00886 ?  90  LYS   B CE  1 
ATOM   3019 N NZ  . LYS   B 1 90  ? 6.16421   -22.26618 -34.64483 1.000 54.91114 ?  90  LYS   B NZ  1 
ATOM   3020 N N   . VAL   B 1 91  ? 10.42573  -18.73151 -36.42771 1.000 40.78196 ?  91  VAL   B N   1 
ATOM   3021 C CA  . VAL   B 1 91  ? 11.34466  -19.12937 -37.48755 1.000 42.14779 ?  91  VAL   B CA  1 
ATOM   3022 C C   . VAL   B 1 91  ? 11.12792  -20.61374 -37.78549 1.000 39.65160 ?  91  VAL   B C   1 
ATOM   3023 O O   . VAL   B 1 91  ? 10.48351  -21.33499 -37.02111 1.000 39.56827 ?  91  VAL   B O   1 
ATOM   3024 C CB  . VAL   B 1 91  ? 12.81500  -18.84031 -37.11116 1.000 37.50978 ?  91  VAL   B CB  1 
ATOM   3025 C CG1 . VAL   B 1 91  ? 13.04557  -17.34432 -37.00032 1.000 37.19788 ?  91  VAL   B CG1 1 
ATOM   3026 C CG2 . VAL   B 1 91  ? 13.17436  -19.53493 -35.80931 1.000 37.42649 ?  91  VAL   B CG2 1 
ATOM   3027 N N   . ASP   B 1 92  ? 11.66735  -21.07371 -38.91810 1.000 44.24279 ?  92  ASP   B N   1 
ATOM   3028 C CA  . ASP   B 1 92  ? 11.44014  -22.45257 -39.34604 1.000 44.95644 ?  92  ASP   B CA  1 
ATOM   3029 C C   . ASP   B 1 92  ? 12.48075  -23.43519 -38.82260 1.000 50.29125 ?  92  ASP   B C   1 
ATOM   3030 O O   . ASP   B 1 92  ? 12.43009  -24.61852 -39.17965 1.000 48.50750 ?  92  ASP   B O   1 
ATOM   3031 C CB  . ASP   B 1 92  ? 11.36620  -22.54207 -40.87845 1.000 49.29253 ?  92  ASP   B CB  1 
ATOM   3032 C CG  . ASP   B 1 92  ? 12.65946  -22.12598 -41.57343 1.000 52.43347 ?  92  ASP   B CG  1 
ATOM   3033 O OD1 . ASP   B 1 92  ? 13.60396  -21.64866 -40.90816 1.000 47.62399 ?  92  ASP   B OD1 1 
ATOM   3034 O OD2 . ASP   B 1 92  ? 12.72140  -22.27299 -42.81586 1.000 55.64257 -1 92  ASP   B OD2 1 
ATOM   3035 N N   . THR   B 1 93  ? 13.40219  -22.98625 -37.96908 1.000 42.85281 ?  93  THR   B N   1 
ATOM   3036 C CA  . THR   B 1 93  ? 14.46268  -23.82718 -37.43736 1.000 47.21651 ?  93  THR   B CA  1 
ATOM   3037 C C   . THR   B 1 93  ? 14.50203  -23.68611 -35.92210 1.000 41.60588 ?  93  THR   B C   1 
ATOM   3038 O O   . THR   B 1 93  ? 14.34057  -22.58377 -35.39932 1.000 42.27779 ?  93  THR   B O   1 
ATOM   3039 C CB  . THR   B 1 93  ? 15.81393  -23.42592 -38.02979 1.000 46.19118 ?  93  THR   B CB  1 
ATOM   3040 O OG1 . THR   B 1 93  ? 15.62528  -23.00183 -39.38655 1.000 56.34305 ?  93  THR   B OG1 1 
ATOM   3041 C CG2 . THR   B 1 93  ? 16.75437  -24.59900 -38.01768 1.000 49.64795 ?  93  THR   B CG2 1 
ATOM   3042 N N   . ALA   B 1 94  ? 14.70114  -24.79825 -35.22068 1.000 41.14879 ?  94  ALA   B N   1 
ATOM   3043 C CA  . ALA   B 1 94  ? 14.86859  -24.75836 -33.77576 1.000 43.94785 ?  94  ALA   B CA  1 
ATOM   3044 C C   . ALA   B 1 94  ? 16.33883  -24.57448 -33.42730 1.000 41.47389 ?  94  ALA   B C   1 
ATOM   3045 O O   . ALA   B 1 94  ? 17.21951  -25.19211 -34.03503 1.000 38.34778 ?  94  ALA   B O   1 
ATOM   3046 C CB  . ALA   B 1 94  ? 14.33106  -26.02705 -33.11745 1.000 39.34821 ?  94  ALA   B CB  1 
ATOM   3047 N N   . ASN   B 1 95  ? 16.60262  -23.73279 -32.42983 1.000 39.81740 ?  95  ASN   B N   1 
ATOM   3048 C CA  . ASN   B 1 95  ? 17.97974  -23.50919 -32.00662 1.000 37.16057 ?  95  ASN   B CA  1 
ATOM   3049 C C   . ASN   B 1 95  ? 18.53247  -24.74766 -31.31439 1.000 35.80810 ?  95  ASN   B C   1 
ATOM   3050 O O   . ASN   B 1 95  ? 18.06511  -25.10318 -30.21731 1.000 37.24099 ?  95  ASN   B O   1 
ATOM   3051 C CB  . ASN   B 1 95  ? 18.05445  -22.28419 -31.08954 1.000 35.79249 ?  95  ASN   B CB  1 
ATOM   3052 C CG  . ASN   B 1 95  ? 19.48557  -21.91749 -30.70149 1.000 37.72585 ?  95  ASN   B CG  1 
ATOM   3053 O OD1 . ASN   B 1 95  ? 20.46605  -22.48443 -31.20417 1.000 35.30314 ?  95  ASN   B OD1 1 
ATOM   3054 N ND2 . ASN   B 1 95  ? 19.60764  -20.95619 -29.79940 1.000 33.49244 ?  95  ASN   B ND2 1 
ATOM   3055 N N   . PRO   B 1 96  ? 19.53917  -25.41768 -31.88775 1.000 36.49658 ?  96  PRO   B N   1 
ATOM   3056 C CA  . PRO   B 1 96  ? 20.08944  -26.61049 -31.23118 1.000 37.88968 ?  96  PRO   B CA  1 
ATOM   3057 C C   . PRO   B 1 96  ? 20.72879  -26.31600 -29.89355 1.000 36.94638 ?  96  PRO   B C   1 
ATOM   3058 O O   . PRO   B 1 96  ? 20.87140  -27.23136 -29.07176 1.000 38.77841 ?  96  PRO   B O   1 
ATOM   3059 C CB  . PRO   B 1 96  ? 21.14404  -27.11744 -32.23157 1.000 39.36891 ?  96  PRO   B CB  1 
ATOM   3060 C CG  . PRO   B 1 96  ? 20.99146  -26.28692 -33.44472 1.000 40.20728 ?  96  PRO   B CG  1 
ATOM   3061 C CD  . PRO   B 1 96  ? 20.36444  -25.00001 -33.02708 1.000 38.28774 ?  96  PRO   B CD  1 
ATOM   3062 N N   . LYS   B 1 97  ? 21.13632  -25.06996 -29.65218 1.000 33.50794 ?  97  LYS   B N   1 
ATOM   3063 C CA  . LYS   B 1 97  ? 21.83711  -24.71033 -28.42818 1.000 33.89096 ?  97  LYS   B CA  1 
ATOM   3064 C C   . LYS   B 1 97  ? 20.90746  -24.14365 -27.35916 1.000 36.26566 ?  97  LYS   B C   1 
ATOM   3065 O O   . LYS   B 1 97  ? 21.39945  -23.60148 -26.36485 1.000 37.00682 ?  97  LYS   B O   1 
ATOM   3066 C CB  . LYS   B 1 97  ? 22.94463  -23.70327 -28.73825 1.000 38.37080 ?  97  LYS   B CB  1 
ATOM   3067 C CG  . LYS   B 1 97  ? 23.95236  -24.18855 -29.77117 1.000 41.17278 ?  97  LYS   B CG  1 
ATOM   3068 C CD  . LYS   B 1 97  ? 24.98800  -23.13069 -30.07123 1.000 43.08056 ?  97  LYS   B CD  1 
ATOM   3069 C CE  . LYS   B 1 97  ? 25.71842  -23.46988 -31.36667 1.000 47.69679 ?  97  LYS   B CE  1 
ATOM   3070 N NZ  . LYS   B 1 97  ? 27.13723  -23.00212 -31.35698 1.000 53.76743 ?  97  LYS   B NZ  1 
ATOM   3071 N N   . THR   B 1 98  ? 19.58743  -24.24495 -27.54241 1.000 37.76779 ?  98  THR   B N   1 
ATOM   3072 C CA  . THR   B 1 98  ? 18.62920  -23.78077 -26.53636 1.000 36.57603 ?  98  THR   B CA  1 
ATOM   3073 C C   . THR   B 1 98  ? 18.88213  -24.47142 -25.20525 1.000 37.41374 ?  98  THR   B C   1 
ATOM   3074 O O   . THR   B 1 98  ? 18.77041  -25.70395 -25.12314 1.000 36.58094 ?  98  THR   B O   1 
ATOM   3075 C CB  . THR   B 1 98  ? 17.18059  -24.03941 -26.94905 1.000 36.38345 ?  98  THR   B CB  1 
ATOM   3076 O OG1 . THR   B 1 98  ? 16.96437  -23.61155 -28.28921 1.000 35.88691 ?  98  THR   B OG1 1 
ATOM   3077 C CG2 . THR   B 1 98  ? 16.22290  -23.26898 -26.02489 1.000 37.89079 ?  98  THR   B CG2 1 
ATOM   3078 N N   . PRO   B 1 99  ? 19.19748  -23.73709 -24.14648 1.000 33.95925 ?  99  PRO   B N   1 
ATOM   3079 C CA  . PRO   B 1 99  ? 19.36476  -24.36006 -22.83714 1.000 33.15250 ?  99  PRO   B CA  1 
ATOM   3080 C C   . PRO   B 1 99  ? 18.01187  -24.58611 -22.18094 1.000 28.56641 ?  99  PRO   B C   1 
ATOM   3081 O O   . PRO   B 1 99  ? 16.97573  -24.12849 -22.66129 1.000 32.04220 ?  99  PRO   B O   1 
ATOM   3082 C CB  . PRO   B 1 99  ? 20.18473  -23.31791 -22.07360 1.000 34.06566 ?  99  PRO   B CB  1 
ATOM   3083 C CG  . PRO   B 1 99  ? 19.67573  -22.02111 -22.61015 1.000 32.64448 ?  99  PRO   B CG  1 
ATOM   3084 C CD  . PRO   B 1 99  ? 19.30433  -22.26423 -24.06967 1.000 34.48624 ?  99  PRO   B CD  1 
ATOM   3085 N N   . LYS   B 1 100 ? 18.03125  -25.30249 -21.06157 1.000 32.82827 ?  100 LYS   B N   1 
ATOM   3086 C CA  . LYS   B 1 100 ? 16.87642  -25.26097 -20.17522 1.000 33.89184 ?  100 LYS   B CA  1 
ATOM   3087 C C   . LYS   B 1 100 ? 16.71086  -23.82797 -19.70073 1.000 32.87406 ?  100 LYS   B C   1 
ATOM   3088 O O   . LYS   B 1 100 ? 17.68953  -23.19478 -19.29954 1.000 34.95240 ?  100 LYS   B O   1 
ATOM   3089 C CB  . LYS   B 1 100 ? 17.05270  -26.18393 -18.97323 1.000 37.02576 ?  100 LYS   B CB  1 
ATOM   3090 C CG  . LYS   B 1 100 ? 17.59229  -27.57310 -19.30515 1.000 46.65925 ?  100 LYS   B CG  1 
ATOM   3091 C CD  . LYS   B 1 100 ? 16.99871  -28.64573 -18.39194 1.000 49.99933 ?  100 LYS   B CD  1 
ATOM   3092 C CE  . LYS   B 1 100 ? 15.76711  -29.30360 -19.04032 1.000 55.30504 ?  100 LYS   B CE  1 
ATOM   3093 N NZ  . LYS   B 1 100 ? 16.12452  -30.10038 -20.26033 1.000 54.53145 ?  100 LYS   B NZ  1 
ATOM   3094 N N   . TYR   B 1 101 ? 15.48328  -23.31386 -19.73659 1.000 32.28256 ?  101 TYR   B N   1 
ATOM   3095 C CA  . TYR   B 1 101 ? 15.30453  -21.89596 -19.44385 1.000 33.21992 ?  101 TYR   B CA  1 
ATOM   3096 C C   . TYR   B 1 101 ? 13.91150  -21.61437 -18.90156 1.000 34.31187 ?  101 TYR   B C   1 
ATOM   3097 O O   . TYR   B 1 101 ? 12.96996  -22.39505 -19.07947 1.000 35.42830 ?  101 TYR   B O   1 
ATOM   3098 C CB  . TYR   B 1 101 ? 15.54983  -21.03094 -20.69004 1.000 30.67139 ?  101 TYR   B CB  1 
ATOM   3099 C CG  . TYR   B 1 101 ? 14.41603  -21.06513 -21.69550 1.000 32.95500 ?  101 TYR   B CG  1 
ATOM   3100 C CD1 . TYR   B 1 101 ? 14.31979  -22.09601 -22.61349 1.000 31.95213 ?  101 TYR   B CD1 1 
ATOM   3101 C CD2 . TYR   B 1 101 ? 13.44690  -20.06390 -21.71863 1.000 32.70313 ?  101 TYR   B CD2 1 
ATOM   3102 C CE1 . TYR   B 1 101 ? 13.29437  -22.13129 -23.53667 1.000 35.93032 ?  101 TYR   B CE1 1 
ATOM   3103 C CE2 . TYR   B 1 101 ? 12.42626  -20.08488 -22.63395 1.000 36.25167 ?  101 TYR   B CE2 1 
ATOM   3104 C CZ  . TYR   B 1 101 ? 12.35244  -21.12841 -23.53967 1.000 38.28183 ?  101 TYR   B CZ  1 
ATOM   3105 O OH  . TYR   B 1 101 ? 11.33865  -21.17450 -24.45095 1.000 40.66473 ?  101 TYR   B OH  1 
ATOM   3106 N N   . LYS   B 1 102 ? 13.79741  -20.46055 -18.24622 1.000 30.44886 ?  102 LYS   B N   1 
ATOM   3107 C CA  . LYS   B 1 102 ? 12.50532  -19.91331 -17.86256 1.000 31.17089 ?  102 LYS   B CA  1 
ATOM   3108 C C   . LYS   B 1 102 ? 12.59228  -18.39749 -17.93881 1.000 30.63481 ?  102 LYS   B C   1 
ATOM   3109 O O   . LYS   B 1 102 ? 13.68219  -17.82752 -17.97323 1.000 29.24461 ?  102 LYS   B O   1 
ATOM   3110 C CB  . LYS   B 1 102 ? 12.07256  -20.36956 -16.45764 1.000 36.96058 ?  102 LYS   B CB  1 
ATOM   3111 C CG  . LYS   B 1 102 ? 13.11996  -20.18636 -15.38055 1.000 40.36046 ?  102 LYS   B CG  1 
ATOM   3112 C CD  . LYS   B 1 102 ? 12.61290  -20.61116 -13.99075 1.000 46.93186 ?  102 LYS   B CD  1 
ATOM   3113 C CE  . LYS   B 1 102 ? 12.74253  -22.11785 -13.74750 1.000 49.43128 ?  102 LYS   B CE  1 
ATOM   3114 N NZ  . LYS   B 1 102 ? 14.16469  -22.58366 -13.63563 1.000 54.05953 ?  102 LYS   B NZ  1 
ATOM   3115 N N   . PHE   B 1 103 ? 11.42729  -17.76131 -17.99998 1.000 29.58989 ?  103 PHE   B N   1 
ATOM   3116 C CA  . PHE   B 1 103 ? 11.30092  -16.30828 -17.95185 1.000 29.64297 ?  103 PHE   B CA  1 
ATOM   3117 C C   . PHE   B 1 103 ? 10.83762  -15.93066 -16.55349 1.000 31.46579 ?  103 PHE   B C   1 
ATOM   3118 O O   . PHE   B 1 103 ? 9.85136   -16.47733 -16.06320 1.000 35.22137 ?  103 PHE   B O   1 
ATOM   3119 C CB  . PHE   B 1 103 ? 10.28888  -15.79859 -18.99158 1.000 29.68250 ?  103 PHE   B CB  1 
ATOM   3120 C CG  . PHE   B 1 103 ? 10.72513  -15.95486 -20.42572 1.000 28.80807 ?  103 PHE   B CG  1 
ATOM   3121 C CD1 . PHE   B 1 103 ? 12.01112  -16.34552 -20.74737 1.000 27.26216 ?  103 PHE   B CD1 1 
ATOM   3122 C CD2 . PHE   B 1 103 ? 9.82139   -15.69724 -21.46443 1.000 28.84018 ?  103 PHE   B CD2 1 
ATOM   3123 C CE1 . PHE   B 1 103 ? 12.40378  -16.46774 -22.07276 1.000 27.58205 ?  103 PHE   B CE1 1 
ATOM   3124 C CE2 . PHE   B 1 103 ? 10.20309  -15.82666 -22.79481 1.000 31.22955 ?  103 PHE   B CE2 1 
ATOM   3125 C CZ  . PHE   B 1 103 ? 11.49903  -16.21222 -23.10036 1.000 28.56267 ?  103 PHE   B CZ  1 
ATOM   3126 N N   . VAL   B 1 104 ? 11.55673  -15.02567 -15.89568 1.000 27.65077 ?  104 VAL   B N   1 
ATOM   3127 C CA  . VAL   B 1 104 ? 11.16689  -14.58564 -14.56223 1.000 26.35425 ?  104 VAL   B CA  1 
ATOM   3128 C C   . VAL   B 1 104 ? 11.20450  -13.06076 -14.50476 1.000 26.27982 ?  104 VAL   B C   1 
ATOM   3129 O O   . VAL   B 1 104 ? 11.89082  -12.40019 -15.28427 1.000 29.79339 ?  104 VAL   B O   1 
ATOM   3130 C CB  . VAL   B 1 104 ? 12.07203  -15.19561 -13.47106 1.000 30.07104 ?  104 VAL   B CB  1 
ATOM   3131 C CG1 . VAL   B 1 104 ? 12.08862  -16.70963 -13.61254 1.000 34.43953 ?  104 VAL   B CG1 1 
ATOM   3132 C CG2 . VAL   B 1 104 ? 13.47632  -14.62546 -13.56132 1.000 31.94455 ?  104 VAL   B CG2 1 
ATOM   3133 N N   . ARG   B 1 105 ? 10.43325  -12.50125 -13.58911 1.000 26.58375 ?  105 ARG   B N   1 
ATOM   3134 C CA  . ARG   B 1 105 ? 10.47073  -11.06911 -13.33423 1.000 27.47293 ?  105 ARG   B CA  1 
ATOM   3135 C C   . ARG   B 1 105 ? 11.21642  -10.84750 -12.02798 1.000 28.11078 ?  105 ARG   B C   1 
ATOM   3136 O O   . ARG   B 1 105 ? 10.80832  -11.35436 -10.97704 1.000 30.12023 ?  105 ARG   B O   1 
ATOM   3137 C CB  . ARG   B 1 105 ? 9.07352   -10.45625 -13.27128 1.000 32.34630 ?  105 ARG   B CB  1 
ATOM   3138 C CG  . ARG   B 1 105 ? 9.13604   -8.92921  -13.33303 1.000 30.82607 ?  105 ARG   B CG  1 
ATOM   3139 C CD  . ARG   B 1 105 ? 7.79207   -8.30509  -13.49004 1.000 30.38177 ?  105 ARG   B CD  1 
ATOM   3140 N NE  . ARG   B 1 105 ? 7.86794   -6.86174  -13.32982 1.000 32.26581 ?  105 ARG   B NE  1 
ATOM   3141 C CZ  . ARG   B 1 105 ? 8.06392   -6.00251  -14.31867 1.000 29.77767 ?  105 ARG   B CZ  1 
ATOM   3142 N NH1 . ARG   B 1 105 ? 8.26171   -6.40862  -15.56778 1.000 26.79223 ?  105 ARG   B NH1 1 
ATOM   3143 N NH2 . ARG   B 1 105 ? 8.05984   -4.70489  -14.05004 1.000 26.46489 ?  105 ARG   B NH2 1 
ATOM   3144 N N   . ILE   B 1 106 ? 12.27925  -10.12496 -12.09634 1.000 25.76928 ?  106 ILE   B N   1 
ATOM   3145 C CA  . ILE   B 1 106 ? 13.18104  -9.98958  -10.95772 1.000 26.54300 ?  106 ILE   B CA  1 
ATOM   3146 C C   . ILE   B 1 106 ? 12.67992  -8.87722  -10.03926 1.000 28.25917 ?  106 ILE   B C   1 
ATOM   3147 O O   . ILE   B 1 106 ? 11.96488  -7.97072  -10.45304 1.000 27.95295 ?  106 ILE   B O   1 
ATOM   3148 C CB  . ILE   B 1 106 ? 14.61688  -9.74907  -11.47221 1.000 26.78213 ?  106 ILE   B CB  1 
ATOM   3149 C CG1 . ILE   B 1 106 ? 15.64639  -10.19651 -10.45251 1.000 36.30949 ?  106 ILE   B CG1 1 
ATOM   3150 C CG2 . ILE   B 1 106 ? 14.84472  -8.29531  -11.86179 1.000 28.78667 ?  106 ILE   B CG2 1 
ATOM   3151 C CD1 . ILE   B 1 106 ? 17.03790  -10.25145 -11.03063 1.000 35.12475 ?  106 ILE   B CD1 1 
ATOM   3152 N N   . GLN   B 1 107 ? 13.04222  -8.95843  -8.75396  1.000 30.74034 ?  107 GLN   B N   1 
ATOM   3153 C CA  . GLN   B 1 107 ? 12.63181  -7.96074  -7.78267  1.000 30.69073 ?  107 GLN   B CA  1 
ATOM   3154 C C   . GLN   B 1 107 ? 13.72666  -6.92530  -7.58289  1.000 30.20370 ?  107 GLN   B C   1 
ATOM   3155 O O   . GLN   B 1 107 ? 14.92259  -7.22942  -7.70524  1.000 29.58617 ?  107 GLN   B O   1 
ATOM   3156 C CB  . GLN   B 1 107 ? 12.32019  -8.62295  -6.43536  1.000 37.70351 ?  107 GLN   B CB  1 
ATOM   3157 C CG  . GLN   B 1 107 ? 11.15101  -9.57745  -6.46321  1.000 39.57013 ?  107 GLN   B CG  1 
ATOM   3158 C CD  . GLN   B 1 107 ? 9.81974   -8.85347  -6.52435  1.000 45.10475 ?  107 GLN   B CD  1 
ATOM   3159 O OE1 . GLN   B 1 107 ? 9.18429   -8.61616  -5.49632  1.000 54.15042 ?  107 GLN   B OE1 1 
ATOM   3160 N NE2 . GLN   B 1 107 ? 9.38661   -8.49795  -7.73425  1.000 47.72815 ?  107 GLN   B NE2 1 
ATOM   3161 N N   . PRO   B 1 108 ? 13.34527  -5.69917  -7.25040  1.000 32.87071 ?  108 PRO   B N   1 
ATOM   3162 C CA  . PRO   B 1 108 ? 14.34955  -4.67568  -6.97539  1.000 30.14839 ?  108 PRO   B CA  1 
ATOM   3163 C C   . PRO   B 1 108 ? 15.31904  -5.15592  -5.90530  1.000 30.62778 ?  108 PRO   B C   1 
ATOM   3164 O O   . PRO   B 1 108 ? 14.92840  -5.79732  -4.92727  1.000 32.49570 ?  108 PRO   B O   1 
ATOM   3165 C CB  . PRO   B 1 108 ? 13.51944  -3.47486  -6.50597  1.000 33.72652 ?  108 PRO   B CB  1 
ATOM   3166 C CG  . PRO   B 1 108 ? 12.12897  -4.01381  -6.25739  1.000 34.68043 ?  108 PRO   B CG  1 
ATOM   3167 C CD  . PRO   B 1 108 ? 11.97025  -5.17384  -7.15520  1.000 34.92963 ?  108 PRO   B CD  1 
ATOM   3168 N N   . GLY   B 1 109 ? 16.59931  -4.90226  -6.14007  1.000 28.37799 ?  109 GLY   B N   1 
ATOM   3169 C CA  . GLY   B 1 109 ? 17.64094  -5.36186  -5.25044  1.000 27.17311 ?  109 GLY   B CA  1 
ATOM   3170 C C   . GLY   B 1 109 ? 18.24944  -6.70491  -5.60717  1.000 29.76579 ?  109 GLY   B C   1 
ATOM   3171 O O   . GLY   B 1 109 ? 19.30297  -7.05825  -5.06856  1.000 30.12519 ?  109 GLY   B O   1 
ATOM   3172 N N   . GLN   B 1 110 ? 17.61503  -7.47409  -6.47990  1.000 25.41584 ?  110 GLN   B N   1 
ATOM   3173 C CA  . GLN   B 1 110 ? 18.20238  -8.72191  -6.92508  1.000 25.76234 ?  110 GLN   B CA  1 
ATOM   3174 C C   . GLN   B 1 110 ? 19.18441  -8.42877  -8.04853  1.000 25.55615 ?  110 GLN   B C   1 
ATOM   3175 O O   . GLN   B 1 110 ? 19.09614  -7.40744  -8.72990  1.000 25.34661 ?  110 GLN   B O   1 
ATOM   3176 C CB  . GLN   B 1 110 ? 17.11515  -9.70790  -7.36326  1.000 30.07047 ?  110 GLN   B CB  1 
ATOM   3177 C CG  . GLN   B 1 110 ? 16.22437  -10.18828 -6.21093  1.000 36.12091 ?  110 GLN   B CG  1 
ATOM   3178 C CD  . GLN   B 1 110 ? 15.19534  -11.25576 -6.61214  1.000 43.38219 ?  110 GLN   B CD  1 
ATOM   3179 O OE1 . GLN   B 1 110 ? 14.45345  -11.11336 -7.58955  1.000 38.52676 ?  110 GLN   B OE1 1 
ATOM   3180 N NE2 . GLN   B 1 110 ? 15.13762  -12.32801 -5.83097  1.000 46.05531 ?  110 GLN   B NE2 1 
ATOM   3181 N N   . THR   B 1 111 ? 20.14986  -9.31602  -8.22188  1.000 23.36906 ?  111 THR   B N   1 
ATOM   3182 C CA  . THR   B 1 111 ? 21.19775  -9.11227  -9.20404  1.000 25.47489 ?  111 THR   B CA  1 
ATOM   3183 C C   . THR   B 1 111 ? 21.00854  -10.07265 -10.36944 1.000 24.71325 ?  111 THR   B C   1 
ATOM   3184 O O   . THR   B 1 111 ? 20.31106  -11.08862 -10.27003 1.000 25.49717 ?  111 THR   B O   1 
ATOM   3185 C CB  . THR   B 1 111 ? 22.57992  -9.30746  -8.58465  1.000 27.53151 ?  111 THR   B CB  1 
ATOM   3186 O OG1 . THR   B 1 111 ? 22.61527  -10.58208 -7.93647  1.000 27.26302 ?  111 THR   B OG1 1 
ATOM   3187 C CG2 . THR   B 1 111 ? 22.85445  -8.16900  -7.55833  1.000 29.42141 ?  111 THR   B CG2 1 
ATOM   3188 N N   . PHE   B 1 112 ? 21.63882  -9.73113  -11.48729 1.000 26.33001 ?  112 PHE   B N   1 
ATOM   3189 C CA  . PHE   B 1 112 ? 21.65328  -10.63353 -12.63175 1.000 23.49316 ?  112 PHE   B CA  1 
ATOM   3190 C C   . PHE   B 1 112 ? 22.85087  -10.28751 -13.49622 1.000 23.49634 ?  112 PHE   B C   1 
ATOM   3191 O O   . PHE   B 1 112 ? 23.46793  -9.23519  -13.34152 1.000 23.72396 ?  112 PHE   B O   1 
ATOM   3192 C CB  . PHE   B 1 112 ? 20.34723  -10.53905 -13.44313 1.000 22.61094 ?  112 PHE   B CB  1 
ATOM   3193 C CG  . PHE   B 1 112 ? 20.00425  -9.14874  -13.89465 1.000 25.01200 ?  112 PHE   B CG  1 
ATOM   3194 C CD1 . PHE   B 1 112 ? 19.31934  -8.27055  -13.05693 1.000 26.56102 ?  112 PHE   B CD1 1 
ATOM   3195 C CD2 . PHE   B 1 112 ? 20.34105  -8.72518  -15.16503 1.000 21.59970 ?  112 PHE   B CD2 1 
ATOM   3196 C CE1 . PHE   B 1 112 ? 18.96328  -6.98796  -13.50958 1.000 29.29131 ?  112 PHE   B CE1 1 
ATOM   3197 C CE2 . PHE   B 1 112 ? 19.99245  -7.44703  -15.61942 1.000 25.49112 ?  112 PHE   B CE2 1 
ATOM   3198 C CZ  . PHE   B 1 112 ? 19.30667  -6.57946  -14.78363 1.000 25.65440 ?  112 PHE   B CZ  1 
ATOM   3199 N N   . SER   B 1 113 ? 23.18439  -11.19342 -14.41459 1.000 22.49394 ?  113 SER   B N   1 
ATOM   3200 C CA  . SER   B 1 113 ? 24.26571  -10.97846 -15.36432 1.000 20.61572 ?  113 SER   B CA  1 
ATOM   3201 C C   . SER   B 1 113 ? 23.70687  -10.44591 -16.67329 1.000 21.38618 ?  113 SER   B C   1 
ATOM   3202 O O   . SER   B 1 113 ? 22.67105  -10.91617 -17.14426 1.000 22.55870 ?  113 SER   B O   1 
ATOM   3203 C CB  . SER   B 1 113 ? 24.99178  -12.29444 -15.63857 1.000 22.65252 ?  113 SER   B CB  1 
ATOM   3204 O OG  . SER   B 1 113 ? 25.59403  -12.78588 -14.44588 1.000 22.85426 ?  113 SER   B OG  1 
ATOM   3205 N N   . VAL   B 1 114 ? 24.42681  -9.52181  -17.29077 1.000 22.21266 ?  114 VAL   B N   1 
ATOM   3206 C CA  . VAL   B 1 114 ? 24.04799  -8.94636  -18.58490 1.000 20.79950 ?  114 VAL   B CA  1 
ATOM   3207 C C   . VAL   B 1 114 ? 25.04909  -9.41008  -19.63242 1.000 21.75866 ?  114 VAL   B C   1 
ATOM   3208 O O   . VAL   B 1 114 ? 26.26071  -9.25482  -19.44142 1.000 22.35954 ?  114 VAL   B O   1 
ATOM   3209 C CB  . VAL   B 1 114 ? 24.04630  -7.41395  -18.50896 1.000 23.43547 ?  114 VAL   B CB  1 
ATOM   3210 C CG1 . VAL   B 1 114 ? 23.94067  -6.80840  -19.94271 1.000 24.54204 ?  114 VAL   B CG1 1 
ATOM   3211 C CG2 . VAL   B 1 114 ? 22.92758  -6.96156  -17.61095 1.000 26.06607 ?  114 VAL   B CG2 1 
ATOM   3212 N N   . LEU   B 1 115 ? 24.54816  -9.94142  -20.76620 1.000 19.49894 ?  115 LEU   B N   1 
ATOM   3213 C CA  . LEU   B 1 115 ? 25.42919  -10.22109 -21.89799 1.000 20.11038 ?  115 LEU   B CA  1 
ATOM   3214 C C   . LEU   B 1 115 ? 25.19293  -9.12307  -22.92340 1.000 23.01926 ?  115 LEU   B C   1 
ATOM   3215 O O   . LEU   B 1 115 ? 24.18696  -9.13556  -23.63604 1.000 24.13669 ?  115 LEU   B O   1 
ATOM   3216 C CB  . LEU   B 1 115 ? 25.16355  -11.60509 -22.46916 1.000 21.15961 ?  115 LEU   B CB  1 
ATOM   3217 C CG  . LEU   B 1 115 ? 26.05792  -11.93146 -23.66372 1.000 24.46802 ?  115 LEU   B CG  1 
ATOM   3218 C CD1 . LEU   B 1 115 ? 27.53824  -12.08107 -23.27136 1.000 24.28167 ?  115 LEU   B CD1 1 
ATOM   3219 C CD2 . LEU   B 1 115 ? 25.52571  -13.16053 -24.39878 1.000 25.68085 ?  115 LEU   B CD2 1 
ATOM   3220 N N   . ALA   B 1 116 ? 26.09765  -8.16096  -22.96120 1.000 22.65723 ?  116 ALA   B N   1 
ATOM   3221 C CA  . ALA   B 1 116 ? 26.00790  -7.05145  -23.89617 1.000 24.41165 ?  116 ALA   B CA  1 
ATOM   3222 C C   . ALA   B 1 116 ? 26.39749  -7.54902  -25.27800 1.000 25.68259 ?  116 ALA   B C   1 
ATOM   3223 O O   . ALA   B 1 116 ? 27.46355  -8.16751  -25.44118 1.000 26.46276 ?  116 ALA   B O   1 
ATOM   3224 C CB  . ALA   B 1 116 ? 26.93046  -5.91216  -23.46215 1.000 24.11507 ?  116 ALA   B CB  1 
ATOM   3225 N N   . CYS   B 1 117 ? 25.52748  -7.27694  -26.27044 1.000 24.29828 ?  117 CYS   B N   1 
ATOM   3226 C CA  . CYS   B 1 117 ? 25.68826  -7.75459  -27.64030 1.000 25.50958 ?  117 CYS   B CA  1 
ATOM   3227 C C   . CYS   B 1 117 ? 25.49060  -6.61487  -28.63987 1.000 26.91435 ?  117 CYS   B C   1 
ATOM   3228 O O   . CYS   B 1 117 ? 24.73392  -5.68060  -28.38718 1.000 23.64904 ?  117 CYS   B O   1 
ATOM   3229 C CB  . CYS   B 1 117 ? 24.67005  -8.83774  -27.98186 1.000 27.27861 ?  117 CYS   B CB  1 
ATOM   3230 S SG  . CYS   B 1 117 ? 24.80086  -10.31547 -26.96738 1.000 30.64476 ?  117 CYS   B SG  1 
ATOM   3231 N N   . TYR   B 1 118 ? 26.19256  -6.70429  -29.76882 1.000 27.97170 ?  118 TYR   B N   1 
ATOM   3232 C CA  . TYR   B 1 118 ? 26.03376  -5.77132  -30.88124 1.000 28.00627 ?  118 TYR   B CA  1 
ATOM   3233 C C   . TYR   B 1 118 ? 25.94383  -6.57983  -32.16765 1.000 30.46978 ?  118 TYR   B C   1 
ATOM   3234 O O   . TYR   B 1 118 ? 26.71221  -7.52413  -32.36960 1.000 30.56996 ?  118 TYR   B O   1 
ATOM   3235 C CB  . TYR   B 1 118 ? 27.17733  -4.73550  -30.91316 1.000 26.16014 ?  118 TYR   B CB  1 
ATOM   3236 C CG  . TYR   B 1 118 ? 27.17040  -3.91947  -29.64089 1.000 27.85158 ?  118 TYR   B CG  1 
ATOM   3237 C CD1 . TYR   B 1 118 ? 26.39796  -2.76756  -29.52518 1.000 28.00416 ?  118 TYR   B CD1 1 
ATOM   3238 C CD2 . TYR   B 1 118 ? 27.86609  -4.34964  -28.51963 1.000 31.03994 ?  118 TYR   B CD2 1 
ATOM   3239 C CE1 . TYR   B 1 118 ? 26.36144  -2.05002  -28.35022 1.000 29.47856 ?  118 TYR   B CE1 1 
ATOM   3240 C CE2 . TYR   B 1 118 ? 27.82233  -3.64264  -27.33835 1.000 31.20531 ?  118 TYR   B CE2 1 
ATOM   3241 C CZ  . TYR   B 1 118 ? 27.07000  -2.50344  -27.25190 1.000 29.60559 ?  118 TYR   B CZ  1 
ATOM   3242 O OH  . TYR   B 1 118 ? 27.02337  -1.81340  -26.07028 1.000 29.36201 ?  118 TYR   B OH  1 
ATOM   3243 N N   . ASN   B 1 119 ? 24.96036  -6.25499  -33.00941 1.000 32.22389 ?  119 ASN   B N   1 
ATOM   3244 C CA  . ASN   B 1 119 ? 24.75418  -6.97267  -34.27207 1.000 34.35267 ?  119 ASN   B CA  1 
ATOM   3245 C C   . ASN   B 1 119 ? 24.67137  -8.48643  -34.07012 1.000 35.16416 ?  119 ASN   B C   1 
ATOM   3246 O O   . ASN   B 1 119 ? 25.18237  -9.27696  -34.87006 1.000 35.72542 ?  119 ASN   B O   1 
ATOM   3247 C CB  . ASN   B 1 119 ? 25.85751  -6.63079  -35.27444 1.000 39.14086 ?  119 ASN   B CB  1 
ATOM   3248 C CG  . ASN   B 1 119 ? 25.90161  -5.16736  -35.61396 1.000 40.33843 ?  119 ASN   B CG  1 
ATOM   3249 O OD1 . ASN   B 1 119 ? 26.78839  -4.43972  -35.15429 1.000 44.27163 ?  119 ASN   B OD1 1 
ATOM   3250 N ND2 . ASN   B 1 119 ? 24.94942  -4.71528  -36.42616 1.000 44.32936 ?  119 ASN   B ND2 1 
ATOM   3251 N N   . GLY   B 1 120 ? 24.01742  -8.90164  -32.99114 1.000 28.66418 ?  120 GLY   B N   1 
ATOM   3252 C CA  . GLY   B 1 120 ? 23.83114  -10.29813 -32.71448 1.000 31.84007 ?  120 GLY   B CA  1 
ATOM   3253 C C   . GLY   B 1 120 ? 25.04342  -11.00190 -32.15060 1.000 31.92492 ?  120 GLY   B C   1 
ATOM   3254 O O   . GLY   B 1 120 ? 24.97739  -12.21635 -31.92076 1.000 33.16235 ?  120 GLY   B O   1 
ATOM   3255 N N   . SER   B 1 121 ? 26.13767  -10.28422 -31.91036 1.000 32.07872 ?  121 SER   B N   1 
ATOM   3256 C CA  . SER   B 1 121 ? 27.38566  -10.90111 -31.44784 1.000 31.19193 ?  121 SER   B CA  1 
ATOM   3257 C C   . SER   B 1 121 ? 27.69973  -10.50001 -30.01768 1.000 30.14528 ?  121 SER   B C   1 
ATOM   3258 O O   . SER   B 1 121 ? 27.69135  -9.30868  -29.70258 1.000 29.02941 ?  121 SER   B O   1 
ATOM   3259 C CB  . SER   B 1 121 ? 28.54816  -10.50389 -32.34922 1.000 37.52061 ?  121 SER   B CB  1 
ATOM   3260 O OG  . SER   B 1 121 ? 28.39662  -11.10085 -33.62499 1.000 43.11867 ?  121 SER   B OG  1 
ATOM   3261 N N   . PRO   B 1 122 ? 27.97246  -11.46966 -29.14372 1.000 30.33029 ?  122 PRO   B N   1 
ATOM   3262 C CA  . PRO   B 1 122 ? 28.28708  -11.14970 -27.74586 1.000 28.54755 ?  122 PRO   B CA  1 
ATOM   3263 C C   . PRO   B 1 122 ? 29.54350  -10.29894 -27.63257 1.000 30.43448 ?  122 PRO   B C   1 
ATOM   3264 O O   . PRO   B 1 122 ? 30.55394  -10.54980 -28.29115 1.000 33.78091 ?  122 PRO   B O   1 
ATOM   3265 C CB  . PRO   B 1 122 ? 28.47033  -12.53523 -27.10957 1.000 28.64240 ?  122 PRO   B CB  1 
ATOM   3266 C CG  . PRO   B 1 122 ? 27.54401  -13.43707 -27.93000 1.000 35.45230 ?  122 PRO   B CG  1 
ATOM   3267 C CD  . PRO   B 1 122 ? 27.74584  -12.91230 -29.35072 1.000 33.79432 ?  122 PRO   B CD  1 
ATOM   3268 N N   . SER   B 1 123 ? 29.48360  -9.28078  -26.77352 1.000 28.77361 ?  123 SER   B N   1 
ATOM   3269 C CA  . SER   B 1 123 ? 30.57283  -8.32613  -26.63362 1.000 27.21096 ?  123 SER   B CA  1 
ATOM   3270 C C   . SER   B 1 123 ? 31.18424  -8.32949  -25.24407 1.000 28.86019 ?  123 SER   B C   1 
ATOM   3271 O O   . SER   B 1 123 ? 32.40723  -8.19476  -25.10301 1.000 29.20334 ?  123 SER   B O   1 
ATOM   3272 C CB  . SER   B 1 123 ? 30.07559  -6.91532  -26.95737 1.000 37.19488 ?  123 SER   B CB  1 
ATOM   3273 O OG  . SER   B 1 123 ? 31.08302  -5.95283  -26.71037 1.000 41.31493 ?  123 SER   B OG  1 
ATOM   3274 N N   . GLY   B 1 124 ? 30.35582  -8.47413  -24.22040 1.000 26.69049 ?  124 GLY   B N   1 
ATOM   3275 C CA  . GLY   B 1 124 ? 30.91999  -8.48886  -22.87588 1.000 23.29234 ?  124 GLY   B CA  1 
ATOM   3276 C C   . GLY   B 1 124 ? 29.87424  -8.93930  -21.88504 1.000 27.70099 ?  124 GLY   B C   1 
ATOM   3277 O O   . GLY   B 1 124 ? 28.68016  -9.00909  -22.19903 1.000 25.04542 ?  124 GLY   B O   1 
ATOM   3278 N N   . VAL   B 1 125 ? 30.33048  -9.25663  -20.67132 1.000 22.37221 ?  125 VAL   B N   1 
ATOM   3279 C CA  . VAL   B 1 125 ? 29.42701  -9.74750  -19.64307 1.000 21.87384 ?  125 VAL   B CA  1 
ATOM   3280 C C   . VAL   B 1 125 ? 29.72694  -9.01183  -18.35158 1.000 26.22962 ?  125 VAL   B C   1 
ATOM   3281 O O   . VAL   B 1 125 ? 30.89129  -8.74551  -18.02585 1.000 26.60256 ?  125 VAL   B O   1 
ATOM   3282 C CB  . VAL   B 1 125 ? 29.49366  -11.29247 -19.47229 1.000 28.85841 ?  125 VAL   B CB  1 
ATOM   3283 C CG1 . VAL   B 1 125 ? 30.79784  -11.74618 -18.86701 1.000 30.90742 ?  125 VAL   B CG1 1 
ATOM   3284 C CG2 . VAL   B 1 125 ? 28.29939  -11.79185 -18.64384 1.000 28.76526 ?  125 VAL   B CG2 1 
ATOM   3285 N N   . TYR   B 1 126 ? 28.66751  -8.63051  -17.64100 1.000 24.76360 ?  126 TYR   B N   1 
ATOM   3286 C CA  . TYR   B 1 126 ? 28.88751  -7.99533  -16.34327 1.000 25.33167 ?  126 TYR   B CA  1 
ATOM   3287 C C   . TYR   B 1 126 ? 27.67183  -8.20221  -15.45885 1.000 25.28098 ?  126 TYR   B C   1 
ATOM   3288 O O   . TYR   B 1 126 ? 26.59092  -8.53641  -15.93130 1.000 22.99893 ?  126 TYR   B O   1 
ATOM   3289 C CB  . TYR   B 1 126 ? 29.19448  -6.50200  -16.46182 1.000 25.92749 ?  126 TYR   B CB  1 
ATOM   3290 C CG  . TYR   B 1 126 ? 28.20716  -5.71369  -17.29474 1.000 24.56767 ?  126 TYR   B CG  1 
ATOM   3291 C CD1 . TYR   B 1 126 ? 27.07089  -5.16382  -16.72735 1.000 27.63854 ?  126 TYR   B CD1 1 
ATOM   3292 C CD2 . TYR   B 1 126 ? 28.42746  -5.52549  -18.64629 1.000 28.86921 ?  126 TYR   B CD2 1 
ATOM   3293 C CE1 . TYR   B 1 126 ? 26.15799  -4.43495  -17.50844 1.000 28.98764 ?  126 TYR   B CE1 1 
ATOM   3294 C CE2 . TYR   B 1 126 ? 27.52795  -4.79822  -19.42544 1.000 29.46216 ?  126 TYR   B CE2 1 
ATOM   3295 C CZ  . TYR   B 1 126 ? 26.40344  -4.27015  -18.84843 1.000 28.78205 ?  126 TYR   B CZ  1 
ATOM   3296 O OH  . TYR   B 1 126 ? 25.52874  -3.54326  -19.64010 1.000 29.69769 ?  126 TYR   B OH  1 
ATOM   3297 N N   . GLN   B 1 127 ? 27.85852  -7.96199  -14.16396 1.000 24.87630 ?  127 GLN   B N   1 
ATOM   3298 C CA  . GLN   B 1 127 ? 26.80626  -8.08880  -13.16259 1.000 22.96828 ?  127 GLN   B CA  1 
ATOM   3299 C C   . GLN   B 1 127 ? 26.12600  -6.73755  -12.88468 1.000 24.33159 ?  127 GLN   B C   1 
ATOM   3300 O O   . GLN   B 1 127 ? 26.80336  -5.71073  -12.77759 1.000 29.32949 ?  127 GLN   B O   1 
ATOM   3301 C CB  . GLN   B 1 127 ? 27.43318  -8.66954  -11.88522 1.000 27.11908 ?  127 GLN   B CB  1 
ATOM   3302 C CG  . GLN   B 1 127 ? 26.45732  -9.20955  -10.89555 1.000 31.42165 ?  127 GLN   B CG  1 
ATOM   3303 C CD  . GLN   B 1 127 ? 25.95207  -10.59422 -11.24871 1.000 31.70692 ?  127 GLN   B CD  1 
ATOM   3304 O OE1 . GLN   B 1 127 ? 26.11543  -11.07745 -12.37779 1.000 31.78111 ?  127 GLN   B OE1 1 
ATOM   3305 N NE2 . GLN   B 1 127 ? 25.31194  -11.23373 -10.29098 1.000 35.30837 ?  127 GLN   B NE2 1 
ATOM   3306 N N   . CYS   B 1 128 ? 24.78750  -6.74744  -12.76337 1.000 26.35038 ?  128 CYS   B N   1 
ATOM   3307 C CA  . CYS   B 1 128 ? 23.94156  -5.57637  -12.51021 1.000 24.93298 ?  128 CYS   B CA  1 
ATOM   3308 C C   . CYS   B 1 128 ? 22.98878  -5.92442  -11.37828 1.000 26.48460 ?  128 CYS   B C   1 
ATOM   3309 O O   . CYS   B 1 128 ? 22.75495  -7.09750  -11.08655 1.000 28.35172 ?  128 CYS   B O   1 
ATOM   3310 C CB  . CYS   B 1 128 ? 23.06556  -5.16798  -13.75526 1.000 26.88707 ?  128 CYS   B CB  1 
ATOM   3311 S SG  . CYS   B 1 128 ? 23.94760  -4.19436  -14.93286 1.000 36.64107 ?  128 CYS   B SG  1 
ATOM   3312 N N   . ALA   B 1 129 ? 22.39027  -4.90340  -10.76842 1.000 27.91382 ?  129 ALA   B N   1 
ATOM   3313 C CA  . ALA   B 1 129 ? 21.26884  -5.10391  -9.86018  1.000 25.57634 ?  129 ALA   B CA  1 
ATOM   3314 C C   . ALA   B 1 129 ? 20.06967  -4.32234  -10.37896 1.000 23.95695 ?  129 ALA   B C   1 
ATOM   3315 O O   . ALA   B 1 129 ? 20.23006  -3.25050  -10.96470 1.000 26.67496 ?  129 ALA   B O   1 
ATOM   3316 C CB  . ALA   B 1 129 ? 21.58847  -4.63508  -8.43768  1.000 28.97016 ?  129 ALA   B CB  1 
ATOM   3317 N N   . MET   B 1 130 ? 18.86952  -4.84732  -10.14970 1.000 22.24709 ?  130 MET   B N   1 
ATOM   3318 C CA  . MET   B 1 130 ? 17.67086  -4.06150  -10.42561 1.000 25.69737 ?  130 MET   B CA  1 
ATOM   3319 C C   . MET   B 1 130 ? 17.55245  -3.01462  -9.31773  1.000 28.05315 ?  130 MET   B C   1 
ATOM   3320 O O   . MET   B 1 130 ? 17.40994  -3.38334  -8.15004  1.000 30.14900 ?  130 MET   B O   1 
ATOM   3321 C CB  . MET   B 1 130 ? 16.44875  -4.97989  -10.49850 1.000 27.27495 ?  130 MET   B CB  1 
ATOM   3322 C CG  . MET   B 1 130 ? 15.09549  -4.27380  -10.75772 1.000 29.01328 ?  130 MET   B CG  1 
ATOM   3323 S SD  . MET   B 1 130 ? 15.13452  -3.28930  -12.26506 1.000 29.25951 ?  130 MET   B SD  1 
ATOM   3324 C CE  . MET   B 1 130 ? 15.31756  -4.54574  -13.53652 1.000 25.74453 ?  130 MET   B CE  1 
ATOM   3325 N N   . ARG   B 1 131 ? 17.65112  -1.72912  -9.66759  1.000 24.76910 ?  131 ARG   B N   1 
ATOM   3326 C CA  . ARG   B 1 131 ? 17.60859  -0.67250  -8.65317  1.000 26.16472 ?  131 ARG   B CA  1 
ATOM   3327 C C   . ARG   B 1 131 ? 16.20709  -0.55107  -8.06350  1.000 27.39931 ?  131 ARG   B C   1 
ATOM   3328 O O   . ARG   B 1 131 ? 15.20705  -0.91946  -8.69867  1.000 26.41914 ?  131 ARG   B O   1 
ATOM   3329 C CB  . ARG   B 1 131 ? 18.00823  0.69205   -9.21315  1.000 27.65781 ?  131 ARG   B CB  1 
ATOM   3330 C CG  . ARG   B 1 131 ? 19.30074  0.80247   -10.03966 1.000 32.17230 ?  131 ARG   B CG  1 
ATOM   3331 C CD  . ARG   B 1 131 ? 20.55618  0.65669   -9.21005  1.000 29.29013 ?  131 ARG   B CD  1 
ATOM   3332 N NE  . ARG   B 1 131 ? 20.50157  1.37418   -7.93584  1.000 29.49185 ?  131 ARG   B NE  1 
ATOM   3333 C CZ  . ARG   B 1 131 ? 21.22921  1.00767   -6.89477  1.000 28.55946 ?  131 ARG   B CZ  1 
ATOM   3334 N NH1 . ARG   B 1 131 ? 22.05654  -0.02303  -6.97502  1.000 25.68735 ?  131 ARG   B NH1 1 
ATOM   3335 N NH2 . ARG   B 1 131 ? 21.12307  1.68665   -5.74679  1.000 28.68123 ?  131 ARG   B NH2 1 
ATOM   3336 N N   . PRO   B 1 132 ? 16.10290  -0.00574  -6.85058  1.000 25.37661 ?  132 PRO   B N   1 
ATOM   3337 C CA  . PRO   B 1 132 ? 14.77159  0.23408   -6.28589  1.000 25.35764 ?  132 PRO   B CA  1 
ATOM   3338 C C   . PRO   B 1 132 ? 13.88560  1.09183   -7.18147  1.000 25.41671 ?  132 PRO   B C   1 
ATOM   3339 O O   . PRO   B 1 132 ? 12.66777  0.92943   -7.12282  1.000 27.60349 ?  132 PRO   B O   1 
ATOM   3340 C CB  . PRO   B 1 132 ? 15.08517  0.90869   -4.94663  1.000 29.67313 ?  132 PRO   B CB  1 
ATOM   3341 C CG  . PRO   B 1 132 ? 16.36807  0.21637   -4.52977  1.000 29.18243 ?  132 PRO   B CG  1 
ATOM   3342 C CD  . PRO   B 1 132 ? 17.16421  0.15649   -5.83629  1.000 26.31893 ?  132 PRO   B CD  1 
ATOM   3343 N N   . ASN   B 1 133 ? 14.45220  1.99172   -7.98520  1.000 23.40356 ?  133 ASN   B N   1 
ATOM   3344 C CA  . ASN   B 1 133 ? 13.66160  2.79263   -8.91728  1.000 23.63313 ?  133 ASN   B CA  1 
ATOM   3345 C C   . ASN   B 1 133 ? 13.54493  2.12724   -10.27994 1.000 26.38000 ?  133 ASN   B C   1 
ATOM   3346 O O   . ASN   B 1 133 ? 13.19123  2.79680   -11.25428 1.000 27.12222 ?  133 ASN   B O   1 
ATOM   3347 C CB  . ASN   B 1 133 ? 14.23433  4.20886   -9.05064  1.000 28.74635 ?  133 ASN   B CB  1 
ATOM   3348 C CG  . ASN   B 1 133 ? 15.56542  4.27478   -9.81679  1.000 28.54472 ?  133 ASN   B CG  1 
ATOM   3349 O OD1 . ASN   B 1 133 ? 16.17214  3.25484   -10.20040 1.000 26.22288 ?  133 ASN   B OD1 1 
ATOM   3350 N ND2 . ASN   B 1 133 ? 16.03172  5.49122   -10.01715 1.000 28.79493 ?  133 ASN   B ND2 1 
ATOM   3351 N N   . PHE   B 1 134 ? 13.87810  0.83792   -10.36044 1.000 25.66762 ?  134 PHE   B N   1 
ATOM   3352 C CA  . PHE   B 1 134 ? 13.66865  -0.00820  -11.53590 1.000 26.81915 ?  134 PHE   B CA  1 
ATOM   3353 C C   . PHE   B 1 134 ? 14.49291  0.41443   -12.73886 1.000 27.46968 ?  134 PHE   B C   1 
ATOM   3354 O O   . PHE   B 1 134 ? 14.15882  0.06775   -13.87356 1.000 27.87970 ?  134 PHE   B O   1 
ATOM   3355 C CB  . PHE   B 1 134 ? 12.17870  -0.08125  -11.89461 1.000 27.15236 ?  134 PHE   B CB  1 
ATOM   3356 C CG  . PHE   B 1 134 ? 11.40208  -0.89841  -10.92024 1.000 28.57385 ?  134 PHE   B CG  1 
ATOM   3357 C CD1 . PHE   B 1 134 ? 11.55315  -2.27962  -10.90764 1.000 30.01449 ?  134 PHE   B CD1 1 
ATOM   3358 C CD2 . PHE   B 1 134 ? 10.59388  -0.30121  -9.97120  1.000 32.04673 ?  134 PHE   B CD2 1 
ATOM   3359 C CE1 . PHE   B 1 134 ? 10.88628  -3.06058  -9.98856  1.000 36.22555 ?  134 PHE   B CE1 1 
ATOM   3360 C CE2 . PHE   B 1 134 ? 9.91844   -1.08000  -9.03653  1.000 31.41135 ?  134 PHE   B CE2 1 
ATOM   3361 C CZ  . PHE   B 1 134 ? 10.05644  -2.45795  -9.05501  1.000 35.85226 ?  134 PHE   B CZ  1 
ATOM   3362 N N   . THR   B 1 135 ? 15.58206  1.12783   -12.52475 1.000 26.34210 ?  135 THR   B N   1 
ATOM   3363 C CA  . THR   B 1 135 ? 16.61857  1.27897   -13.52864 1.000 25.21058 ?  135 THR   B CA  1 
ATOM   3364 C C   . THR   B 1 135 ? 17.72478  0.26949   -13.24404 1.000 26.17693 ?  135 THR   B C   1 
ATOM   3365 O O   . THR   B 1 135 ? 17.71017  -0.42299  -12.22807 1.000 25.59602 ?  135 THR   B O   1 
ATOM   3366 C CB  . THR   B 1 135 ? 17.17183  2.70690   -13.51605 1.000 26.24649 ?  135 THR   B CB  1 
ATOM   3367 O OG1 . THR   B 1 135 ? 17.82470  2.96307   -12.25907 1.000 26.87183 ?  135 THR   B OG1 1 
ATOM   3368 C CG2 . THR   B 1 135 ? 16.03825  3.69909   -13.69117 1.000 28.70650 ?  135 THR   B CG2 1 
ATOM   3369 N N   . ILE   B 1 136 ? 18.66199  0.15016   -14.17757 1.000 25.24629 ?  136 ILE   B N   1 
ATOM   3370 C CA  . ILE   B 1 136 ? 19.90370  -0.57182  -13.91480 1.000 24.66993 ?  136 ILE   B CA  1 
ATOM   3371 C C   . ILE   B 1 136 ? 21.07427  0.29857   -14.35844 1.000 27.21951 ?  136 ILE   B C   1 
ATOM   3372 O O   . ILE   B 1 136 ? 20.95989  1.14238   -15.25304 1.000 25.40810 ?  136 ILE   B O   1 
ATOM   3373 C CB  . ILE   B 1 136 ? 19.93339  -1.95758  -14.60387 1.000 29.22759 ?  136 ILE   B CB  1 
ATOM   3374 C CG1 . ILE   B 1 136 ? 20.06582  -1.83014  -16.11354 1.000 25.29794 ?  136 ILE   B CG1 1 
ATOM   3375 C CG2 . ILE   B 1 136 ? 18.65138  -2.78071  -14.27442 1.000 27.19504 ?  136 ILE   B CG2 1 
ATOM   3376 C CD1 . ILE   B 1 136 ? 20.30756  -3.20247  -16.80135 1.000 27.41140 ?  136 ILE   B CD1 1 
ATOM   3377 N N   . LYS   B 1 137 ? 22.19688  0.16008   -13.67494 1.000 25.83312 ?  137 LYS   B N   1 
ATOM   3378 C CA  . LYS   B 1 137 ? 23.38090  0.93175   -14.03342 1.000 27.07716 ?  137 LYS   B CA  1 
ATOM   3379 C C   . LYS   B 1 137 ? 24.24085  0.00597   -14.88733 1.000 31.78421 ?  137 LYS   B C   1 
ATOM   3380 O O   . LYS   B 1 137 ? 25.09800  -0.73129  -14.38547 1.000 32.15201 ?  137 LYS   B O   1 
ATOM   3381 C CB  . LYS   B 1 137 ? 24.11332  1.43326   -12.79621 1.000 28.25697 ?  137 LYS   B CB  1 
ATOM   3382 C CG  . LYS   B 1 137 ? 23.26182  2.35386   -11.89653 1.000 30.24846 ?  137 LYS   B CG  1 
ATOM   3383 C CD  . LYS   B 1 137 ? 24.03127  2.62332   -10.57576 1.000 37.17301 ?  137 LYS   B CD  1 
ATOM   3384 C CE  . LYS   B 1 137 ? 23.19669  3.35731   -9.53362  1.000 39.48897 ?  137 LYS   B CE  1 
ATOM   3385 N NZ  . LYS   B 1 137 ? 23.99947  3.57690   -8.27132  1.000 43.31504 ?  137 LYS   B NZ  1 
ATOM   3386 N N   . GLY   B 1 138 ? 23.98563  0.03111   -16.19224 1.000 29.09579 ?  138 GLY   B N   1 
ATOM   3387 C CA  . GLY   B 1 138 ? 24.65662  -0.83716  -17.12911 1.000 29.17321 ?  138 GLY   B CA  1 
ATOM   3388 C C   . GLY   B 1 138 ? 25.68514  -0.09935  -17.96030 1.000 28.74739 ?  138 GLY   B C   1 
ATOM   3389 O O   . GLY   B 1 138 ? 26.04550  1.05098   -17.70406 1.000 32.14316 ?  138 GLY   B O   1 
ATOM   3390 N N   . SER   B 1 139 ? 26.17641  -0.79630  -18.96887 1.000 26.84819 ?  139 SER   B N   1 
ATOM   3391 C CA  . SER   B 1 139 ? 27.14633  -0.26145  -19.91664 1.000 30.91623 ?  139 SER   B CA  1 
ATOM   3392 C C   . SER   B 1 139 ? 26.66908  -0.72069  -21.29139 1.000 31.03640 ?  139 SER   B C   1 
ATOM   3393 O O   . SER   B 1 139 ? 26.85571  -1.87731  -21.67975 1.000 29.87641 ?  139 SER   B O   1 
ATOM   3394 C CB  . SER   B 1 139 ? 28.55595  -0.75197  -19.59781 1.000 36.60512 ?  139 SER   B CB  1 
ATOM   3395 O OG  . SER   B 1 139 ? 29.48511  -0.29490  -20.56502 1.000 40.15154 ?  139 SER   B OG  1 
ATOM   3396 N N   . PHE   B 1 140 ? 26.00310  0.17845   -22.00697 1.000 29.68265 ?  140 PHE   B N   1 
ATOM   3397 C CA  . PHE   B 1 140 ? 25.33149  -0.16310  -23.24548 1.000 29.87604 ?  140 PHE   B CA  1 
ATOM   3398 C C   . PHE   B 1 140 ? 25.55173  0.96669   -24.24150 1.000 28.76062 ?  140 PHE   B C   1 
ATOM   3399 O O   . PHE   B 1 140 ? 25.53261  2.14513   -23.86741 1.000 32.41042 ?  140 PHE   B O   1 
ATOM   3400 C CB  . PHE   B 1 140 ? 23.82159  -0.34204  -23.06140 1.000 28.63597 ?  140 PHE   B CB  1 
ATOM   3401 C CG  . PHE   B 1 140 ? 23.40160  -1.54433  -22.27676 1.000 25.20061 ?  140 PHE   B CG  1 
ATOM   3402 C CD1 . PHE   B 1 140 ? 23.56135  -2.83370  -22.77690 1.000 28.93953 ?  140 PHE   B CD1 1 
ATOM   3403 C CD2 . PHE   B 1 140 ? 22.74193  -1.38062  -21.08049 1.000 26.45302 ?  140 PHE   B CD2 1 
ATOM   3404 C CE1 . PHE   B 1 140 ? 23.10479  -3.93334  -22.05631 1.000 25.93284 ?  140 PHE   B CE1 1 
ATOM   3405 C CE2 . PHE   B 1 140 ? 22.28657  -2.46755  -20.35618 1.000 28.11763 ?  140 PHE   B CE2 1 
ATOM   3406 C CZ  . PHE   B 1 140 ? 22.46179  -3.75456  -20.85591 1.000 24.85983 ?  140 PHE   B CZ  1 
ATOM   3407 N N   . LEU   B 1 141 ? 25.77105  0.60642   -25.49233 1.000 30.03538 ?  141 LEU   B N   1 
ATOM   3408 C CA  . LEU   B 1 141 ? 25.98583  1.57059   -26.56258 1.000 33.88597 ?  141 LEU   B CA  1 
ATOM   3409 C C   . LEU   B 1 141 ? 24.89317  1.41116   -27.61402 1.000 30.97807 ?  141 LEU   B C   1 
ATOM   3410 O O   . LEU   B 1 141 ? 24.00107  0.57374   -27.49005 1.000 31.15878 ?  141 LEU   B O   1 
ATOM   3411 C CB  . LEU   B 1 141 ? 27.36498  1.38240   -27.19400 1.000 32.22515 ?  141 LEU   B CB  1 
ATOM   3412 C CG  . LEU   B 1 141 ? 28.58328  1.48567   -26.27160 1.000 33.98069 ?  141 LEU   B CG  1 
ATOM   3413 C CD1 . LEU   B 1 141 ? 29.79120  1.09494   -27.07519 1.000 40.07060 ?  141 LEU   B CD1 1 
ATOM   3414 C CD2 . LEU   B 1 141 ? 28.72873  2.89521   -25.71744 1.000 39.01416 ?  141 LEU   B CD2 1 
ATOM   3415 N N   . ASN   B 1 142 ? 24.97157  2.22645   -28.66498 1.000 33.19498 ?  142 ASN   B N   1 
ATOM   3416 C CA  . ASN   B 1 142 ? 24.08712  2.04197   -29.81161 1.000 32.43689 ?  142 ASN   B CA  1 
ATOM   3417 C C   . ASN   B 1 142 ? 24.20988  0.62833   -30.35963 1.000 34.96218 ?  142 ASN   B C   1 
ATOM   3418 O O   . ASN   B 1 142 ? 25.31665  0.10194   -30.51611 1.000 36.87750 ?  142 ASN   B O   1 
ATOM   3419 C CB  . ASN   B 1 142 ? 24.43052  3.04750   -30.90810 1.000 35.10828 ?  142 ASN   B CB  1 
ATOM   3420 C CG  . ASN   B 1 142 ? 23.49803  4.23764   -30.91911 1.000 43.38798 ?  142 ASN   B CG  1 
ATOM   3421 O OD1 . ASN   B 1 142 ? 22.35222  4.15259   -30.46740 1.000 47.61955 ?  142 ASN   B OD1 1 
ATOM   3422 N ND2 . ASN   B 1 142 ? 23.97089  5.35017   -31.45823 1.000 41.27320 ?  142 ASN   B ND2 1 
ATOM   3423 N N   . GLY   B 1 143 ? 23.06909  0.01273   -30.66024 1.000 30.21780 ?  143 GLY   B N   1 
ATOM   3424 C CA  . GLY   B 1 143 ? 23.04327  -1.32824  -31.18675 1.000 30.16564 ?  143 GLY   B CA  1 
ATOM   3425 C C   . GLY   B 1 143 ? 22.88670  -2.40687  -30.14116 1.000 26.23529 ?  143 GLY   B C   1 
ATOM   3426 O O   . GLY   B 1 143 ? 22.79514  -3.57740  -30.50472 1.000 30.34629 ?  143 GLY   B O   1 
ATOM   3427 N N   . SER   B 1 144 ? 22.80703  -2.03958  -28.86305 1.000 29.00326 ?  144 SER   B N   1 
ATOM   3428 C CA  . SER   B 1 144 ? 22.78938  -2.99887  -27.75948 1.000 25.37749 ?  144 SER   B CA  1 
ATOM   3429 C C   . SER   B 1 144 ? 21.39334  -3.44395  -27.35436 1.000 24.64049 ?  144 SER   B C   1 
ATOM   3430 O O   . SER   B 1 144 ? 21.26362  -4.35821  -26.53773 1.000 23.09287 ?  144 SER   B O   1 
ATOM   3431 C CB  . SER   B 1 144 ? 23.47565  -2.38385  -26.53420 1.000 28.24603 ?  144 SER   B CB  1 
ATOM   3432 O OG  . SER   B 1 144 ? 22.76961  -1.23758  -26.05958 1.000 25.01982 ?  144 SER   B OG  1 
ATOM   3433 N N   . CYS   B 1 145 ? 20.33015  -2.83647  -27.88735 1.000 25.14360 ?  145 CYS   B N   1 
ATOM   3434 C CA  . CYS   B 1 145 ? 19.01058  -3.28507  -27.46694 1.000 23.31585 ?  145 CYS   B CA  1 
ATOM   3435 C C   . CYS   B 1 145 ? 18.79050  -4.73887  -27.86142 1.000 23.22660 ?  145 CYS   B C   1 
ATOM   3436 O O   . CYS   B 1 145 ? 19.31962  -5.23473  -28.86250 1.000 24.45667 ?  145 CYS   B O   1 
ATOM   3437 C CB  . CYS   B 1 145 ? 17.91982  -2.37302  -28.05141 1.000 25.12515 ?  145 CYS   B CB  1 
ATOM   3438 S SG  . CYS   B 1 145 ? 17.90641  -0.79602  -27.23501 1.000 26.61714 ?  145 CYS   B SG  1 
ATOM   3439 N N   . GLY   B 1 146 ? 18.01558  -5.44175  -27.05386 1.000 21.00906 ?  146 GLY   B N   1 
ATOM   3440 C CA  . GLY   B 1 146 ? 17.84756  -6.86198  -27.22385 1.000 21.82849 ?  146 GLY   B CA  1 
ATOM   3441 C C   . GLY   B 1 146 ? 18.86181  -7.68835  -26.45830 1.000 22.62482 ?  146 GLY   B C   1 
ATOM   3442 O O   . GLY   B 1 146 ? 18.67198  -8.90483  -26.32059 1.000 23.28546 ?  146 GLY   B O   1 
ATOM   3443 N N   . SER   B 1 147 ? 19.92944  -7.06489  -25.96806 1.000 23.35021 ?  147 SER   B N   1 
ATOM   3444 C CA  . SER   B 1 147 ? 20.79873  -7.74711  -25.01395 1.000 20.90181 ?  147 SER   B CA  1 
ATOM   3445 C C   . SER   B 1 147 ? 19.95415  -8.16829  -23.82222 1.000 23.28632 ?  147 SER   B C   1 
ATOM   3446 O O   . SER   B 1 147 ? 18.97725  -7.48688  -23.47231 1.000 21.23232 ?  147 SER   B O   1 
ATOM   3447 C CB  . SER   B 1 147 ? 21.91901  -6.81564  -24.53506 1.000 23.10159 ?  147 SER   B CB  1 
ATOM   3448 O OG  . SER   B 1 147 ? 22.79673  -6.41585  -25.58208 1.000 23.84949 ?  147 SER   B OG  1 
ATOM   3449 N N   . VAL   B 1 148 ? 20.35547  -9.26626  -23.15693 1.000 23.07097 ?  148 VAL   B N   1 
ATOM   3450 C CA  . VAL   B 1 148 ? 19.52340  -9.81522  -22.09480 1.000 21.75658 ?  148 VAL   B CA  1 
ATOM   3451 C C   . VAL   B 1 148 ? 20.31396  -9.97087  -20.80625 1.000 23.69612 ?  148 VAL   B C   1 
ATOM   3452 O O   . VAL   B 1 148 ? 21.54767  -10.05050 -20.79442 1.000 21.20519 ?  148 VAL   B O   1 
ATOM   3453 C CB  . VAL   B 1 148 ? 18.85667  -11.16580 -22.42713 1.000 23.51853 ?  148 VAL   B CB  1 
ATOM   3454 C CG1 . VAL   B 1 148 ? 17.91965  -10.99704 -23.62759 1.000 23.15570 ?  148 VAL   B CG1 1 
ATOM   3455 C CG2 . VAL   B 1 148 ? 19.89322  -12.25993 -22.64007 1.000 25.47201 ?  148 VAL   B CG2 1 
ATOM   3456 N N   . GLY   B 1 149 ? 19.54174  -10.02486 -19.71839 1.000 20.54561 ?  149 GLY   B N   1 
ATOM   3457 C CA  . GLY   B 1 149 ? 20.05684  -10.29255 -18.37897 1.000 20.75855 ?  149 GLY   B CA  1 
ATOM   3458 C C   . GLY   B 1 149 ? 19.48613  -11.61144 -17.89055 1.000 22.41856 ?  149 GLY   B C   1 
ATOM   3459 O O   . GLY   B 1 149 ? 18.38479  -12.01780 -18.28151 1.000 25.17243 ?  149 GLY   B O   1 
ATOM   3460 N N   . PHE   B 1 150 ? 20.24627  -12.30241 -17.04885 1.000 21.11737 ?  150 PHE   B N   1 
ATOM   3461 C CA  . PHE   B 1 150 ? 19.90089  -13.67157 -16.72403 1.000 22.30883 ?  150 PHE   B CA  1 
ATOM   3462 C C   . PHE   B 1 150 ? 20.62481  -14.08538 -15.45978 1.000 22.18210 ?  150 PHE   B C   1 
ATOM   3463 O O   . PHE   B 1 150 ? 21.62837  -13.48709 -15.07142 1.000 21.18756 ?  150 PHE   B O   1 
ATOM   3464 C CB  . PHE   B 1 150 ? 20.30103  -14.63979 -17.84757 1.000 23.29521 ?  150 PHE   B CB  1 
ATOM   3465 C CG  . PHE   B 1 150 ? 21.76677  -14.63171 -18.13321 1.000 24.52009 ?  150 PHE   B CG  1 
ATOM   3466 C CD1 . PHE   B 1 150 ? 22.31922  -13.64423 -18.94006 1.000 25.63097 ?  150 PHE   B CD1 1 
ATOM   3467 C CD2 . PHE   B 1 150 ? 22.60615  -15.58841 -17.57717 1.000 24.11483 ?  150 PHE   B CD2 1 
ATOM   3468 C CE1 . PHE   B 1 150 ? 23.69569  -13.59704 -19.17884 1.000 26.77364 ?  150 PHE   B CE1 1 
ATOM   3469 C CE2 . PHE   B 1 150 ? 23.96020  -15.56366 -17.82487 1.000 25.04073 ?  150 PHE   B CE2 1 
ATOM   3470 C CZ  . PHE   B 1 150 ? 24.50929  -14.56579 -18.63724 1.000 26.75340 ?  150 PHE   B CZ  1 
ATOM   3471 N N   . ASN   B 1 151 ? 20.10631  -15.14237 -14.85347 1.000 23.82859 ?  151 ASN   B N   1 
ATOM   3472 C CA  . ASN   B 1 151 ? 20.80719  -15.89012 -13.82201 1.000 25.67803 ?  151 ASN   B CA  1 
ATOM   3473 C C   . ASN   B 1 151 ? 20.83919  -17.34991 -14.25349 1.000 25.22149 ?  151 ASN   B C   1 
ATOM   3474 O O   . ASN   B 1 151 ? 20.07230  -17.77099 -15.12107 1.000 26.83977 ?  151 ASN   B O   1 
ATOM   3475 C CB  . ASN   B 1 151 ? 20.12950  -15.73406 -12.45918 1.000 28.57186 ?  151 ASN   B CB  1 
ATOM   3476 C CG  . ASN   B 1 151 ? 20.39324  -14.37349 -11.83593 1.000 30.65308 ?  151 ASN   B CG  1 
ATOM   3477 O OD1 . ASN   B 1 151 ? 21.48917  -14.11341 -11.35651 1.000 30.98723 ?  151 ASN   B OD1 1 
ATOM   3478 N ND2 . ASN   B 1 151 ? 19.39901  -13.49119 -11.87075 1.000 28.08525 ?  151 ASN   B ND2 1 
ATOM   3479 N N   . ILE   B 1 152 ? 21.75610  -18.11790 -13.66702 1.000 28.75896 ?  152 ILE   B N   1 
ATOM   3480 C CA  . ILE   B 1 152 ? 21.85766  -19.54324 -13.95009 1.000 30.88353 ?  152 ILE   B CA  1 
ATOM   3481 C C   . ILE   B 1 152 ? 21.78207  -20.29298 -12.63173 1.000 34.74824 ?  152 ILE   B C   1 
ATOM   3482 O O   . ILE   B 1 152 ? 22.51056  -19.97473 -11.68347 1.000 34.78075 ?  152 ILE   B O   1 
ATOM   3483 C CB  . ILE   B 1 152 ? 23.15123  -19.88817 -14.70640 1.000 32.13085 ?  152 ILE   B CB  1 
ATOM   3484 C CG1 . ILE   B 1 152 ? 23.24502  -19.03930 -15.97056 1.000 29.41870 ?  152 ILE   B CG1 1 
ATOM   3485 C CG2 . ILE   B 1 152 ? 23.14530  -21.36338 -15.09263 1.000 36.17232 ?  152 ILE   B CG2 1 
ATOM   3486 C CD1 . ILE   B 1 152 ? 24.44039  -19.32674 -16.83956 1.000 33.02070 ?  152 ILE   B CD1 1 
ATOM   3487 N N   . ASP   B 1 153 ? 20.89739  -21.27721 -12.57172 1.000 36.88459 ?  153 ASP   B N   1 
ATOM   3488 C CA  . ASP   B 1 153 ? 20.74309  -22.11558 -11.39150 1.000 41.10541 ?  153 ASP   B CA  1 
ATOM   3489 C C   . ASP   B 1 153 ? 20.86615  -23.55616 -11.85195 1.000 46.42485 ?  153 ASP   B C   1 
ATOM   3490 O O   . ASP   B 1 153 ? 20.06768  -24.01306 -12.67761 1.000 44.22273 ?  153 ASP   B O   1 
ATOM   3491 C CB  . ASP   B 1 153 ? 19.40001  -21.84631 -10.71256 1.000 41.98950 ?  153 ASP   B CB  1 
ATOM   3492 C CG  . ASP   B 1 153 ? 19.27042  -20.39891 -10.23405 1.000 49.88540 ?  153 ASP   B CG  1 
ATOM   3493 O OD1 . ASP   B 1 153 ? 19.79710  -20.07516 -9.14273  1.000 54.53765 ?  153 ASP   B OD1 1 
ATOM   3494 O OD2 . ASP   B 1 153 ? 18.67366  -19.57578 -10.96497 1.000 45.37584 -1 153 ASP   B OD2 1 
ATOM   3495 N N   . TYR   B 1 154 ? 21.88629  -24.24863 -11.35044 1.000 49.80248 ?  154 TYR   B N   1 
ATOM   3496 C CA  . TYR   B 1 154 ? 22.28055  -25.54226 -11.88891 1.000 54.65472 ?  154 TYR   B CA  1 
ATOM   3497 C C   . TYR   B 1 154 ? 22.54240  -25.40977 -13.38449 1.000 50.03405 ?  154 TYR   B C   1 
ATOM   3498 O O   . TYR   B 1 154 ? 23.55166  -24.82441 -13.79083 1.000 55.00796 ?  154 TYR   B O   1 
ATOM   3499 C CB  . TYR   B 1 154 ? 21.21304  -26.59902 -11.59817 1.000 55.93738 ?  154 TYR   B CB  1 
ATOM   3500 C CG  . TYR   B 1 154 ? 20.90587  -26.75417 -10.12268 1.000 65.51475 ?  154 TYR   B CG  1 
ATOM   3501 C CD1 . TYR   B 1 154 ? 21.76712  -27.45422 -9.28476  1.000 70.00140 ?  154 TYR   B CD1 1 
ATOM   3502 C CD2 . TYR   B 1 154 ? 19.75700  -26.20179 -9.56760  1.000 68.91034 ?  154 TYR   B CD2 1 
ATOM   3503 C CE1 . TYR   B 1 154 ? 21.49400  -27.60014 -7.93945  1.000 75.18720 ?  154 TYR   B CE1 1 
ATOM   3504 C CE2 . TYR   B 1 154 ? 19.47569  -26.34282 -8.21565  1.000 75.99883 ?  154 TYR   B CE2 1 
ATOM   3505 C CZ  . TYR   B 1 154 ? 20.34918  -27.04433 -7.40934  1.000 78.83530 ?  154 TYR   B CZ  1 
ATOM   3506 O OH  . TYR   B 1 154 ? 20.07847  -27.19241 -6.06790  1.000 84.15369 ?  154 TYR   B OH  1 
ATOM   3507 N N   . ASP   B 1 155 ? 21.64102  -25.93436 -14.21281 1.000 46.02146 ?  155 ASP   B N   1 
ATOM   3508 C CA  . ASP   B 1 155 ? 21.79070  -25.84994 -15.66060 1.000 46.91367 ?  155 ASP   B CA  1 
ATOM   3509 C C   . ASP   B 1 155 ? 20.62878  -25.10623 -16.31596 1.000 45.99520 ?  155 ASP   B C   1 
ATOM   3510 O O   . ASP   B 1 155 ? 20.39407  -25.26679 -17.51734 1.000 44.69763 ?  155 ASP   B O   1 
ATOM   3511 C CB  . ASP   B 1 155 ? 21.93779  -27.25098 -16.26368 1.000 51.99535 ?  155 ASP   B CB  1 
ATOM   3512 C CG  . ASP   B 1 155 ? 20.73251  -28.14617 -15.98641 1.000 50.47803 ?  155 ASP   B CG  1 
ATOM   3513 O OD1 . ASP   B 1 155 ? 19.86351  -27.77167 -15.16753 1.000 53.57483 ?  155 ASP   B OD1 1 
ATOM   3514 O OD2 . ASP   B 1 155 ? 20.65576  -29.23384 -16.59156 1.000 52.77968 -1 155 ASP   B OD2 1 
ATOM   3515 N N   . CYS   B 1 156 ? 19.89320  -24.30037 -15.55426 1.000 41.11030 ?  156 CYS   B N   1 
ATOM   3516 C CA  . CYS   B 1 156 ? 18.71377  -23.61006 -16.05326 1.000 36.88604 ?  156 CYS   B CA  1 
ATOM   3517 C C   . CYS   B 1 156 ? 18.96769  -22.10641 -16.07990 1.000 34.10985 ?  156 CYS   B C   1 
ATOM   3518 O O   . CYS   B 1 156 ? 19.38913  -21.52175 -15.07157 1.000 34.07075 ?  156 CYS   B O   1 
ATOM   3519 C CB  . CYS   B 1 156 ? 17.49109  -23.92955 -15.18974 1.000 40.70100 ?  156 CYS   B CB  1 
ATOM   3520 S SG  . CYS   B 1 156 ? 15.96838  -23.22180 -15.82112 1.000 44.83404 ?  156 CYS   B SG  1 
ATOM   3521 N N   . VAL   B 1 157 ? 18.71917  -21.49518 -17.23430 1.000 31.62898 ?  157 VAL   B N   1 
ATOM   3522 C CA  . VAL   B 1 157 ? 18.88234  -20.05855 -17.41897 1.000 29.72627 ?  157 VAL   B CA  1 
ATOM   3523 C C   . VAL   B 1 157 ? 17.54462  -19.38658 -17.13738 1.000 29.42205 ?  157 VAL   B C   1 
ATOM   3524 O O   . VAL   B 1 157 ? 16.54303  -19.68508 -17.79697 1.000 29.21864 ?  157 VAL   B O   1 
ATOM   3525 C CB  . VAL   B 1 157 ? 19.36691  -19.73116 -18.84020 1.000 26.43918 ?  157 VAL   B CB  1 
ATOM   3526 C CG1 . VAL   B 1 157 ? 19.56129  -18.22505 -19.00026 1.000 25.50252 ?  157 VAL   B CG1 1 
ATOM   3527 C CG2 . VAL   B 1 157 ? 20.64960  -20.45627 -19.16671 1.000 32.58465 ?  157 VAL   B CG2 1 
ATOM   3528 N N   . SER   B 1 158 ? 17.52849  -18.45292 -16.17982 1.000 25.84446 ?  158 SER   B N   1 
ATOM   3529 C CA  . SER   B 1 158 ? 16.35424  -17.63796 -15.88696 1.000 26.98941 ?  158 SER   B CA  1 
ATOM   3530 C C   . SER   B 1 158 ? 16.58541  -16.28504 -16.53709 1.000 23.45259 ?  158 SER   B C   1 
ATOM   3531 O O   . SER   B 1 158 ? 17.42604  -15.51207 -16.08225 1.000 23.17726 ?  158 SER   B O   1 
ATOM   3532 C CB  . SER   B 1 158 ? 16.13484  -17.47631 -14.37966 1.000 29.24069 ?  158 SER   B CB  1 
ATOM   3533 O OG  . SER   B 1 158 ? 15.83204  -18.71520 -13.75336 1.000 37.61186 ?  158 SER   B OG  1 
ATOM   3534 N N   . PHE   B 1 159 ? 15.88066  -16.01969 -17.62076 1.000 24.34206 ?  159 PHE   B N   1 
ATOM   3535 C CA  . PHE   B 1 159 ? 16.00017  -14.73113 -18.28591 1.000 25.16505 ?  159 PHE   B CA  1 
ATOM   3536 C C   . PHE   B 1 159 ? 15.12458  -13.72302 -17.57322 1.000 26.47061 ?  159 PHE   B C   1 
ATOM   3537 O O   . PHE   B 1 159 ? 13.93681  -13.97729 -17.36414 1.000 27.12244 ?  159 PHE   B O   1 
ATOM   3538 C CB  . PHE   B 1 159 ? 15.56933  -14.85924 -19.74942 1.000 23.17976 ?  159 PHE   B CB  1 
ATOM   3539 C CG  . PHE   B 1 159 ? 16.51474  -15.67414 -20.57632 1.000 23.83848 ?  159 PHE   B CG  1 
ATOM   3540 C CD1 . PHE   B 1 159 ? 17.72681  -15.14768 -20.96475 1.000 24.05391 ?  159 PHE   B CD1 1 
ATOM   3541 C CD2 . PHE   B 1 159 ? 16.18333  -16.96627 -20.97311 1.000 27.21768 ?  159 PHE   B CD2 1 
ATOM   3542 C CE1 . PHE   B 1 159 ? 18.61768  -15.90193 -21.74560 1.000 26.56132 ?  159 PHE   B CE1 1 
ATOM   3543 C CE2 . PHE   B 1 159 ? 17.05931  -17.72239 -21.73966 1.000 26.07184 ?  159 PHE   B CE2 1 
ATOM   3544 C CZ  . PHE   B 1 159 ? 18.27449  -17.18577 -22.13227 1.000 27.97346 ?  159 PHE   B CZ  1 
ATOM   3545 N N   . CYS   B 1 160 ? 15.69894  -12.57300 -17.20112 1.000 25.40783 ?  160 CYS   B N   1 
ATOM   3546 C CA  . CYS   B 1 160 ? 14.92709  -11.59472 -16.44566 1.000 25.94448 ?  160 CYS   B CA  1 
ATOM   3547 C C   . CYS   B 1 160 ? 14.89240  -10.20209 -17.06720 1.000 23.72965 ?  160 CYS   B C   1 
ATOM   3548 O O   . CYS   B 1 160 ? 14.09343  -9.37256  -16.61809 1.000 24.24125 ?  160 CYS   B O   1 
ATOM   3549 C CB  . CYS   B 1 160 ? 15.46353  -11.49896 -14.99855 1.000 27.35181 ?  160 CYS   B CB  1 
ATOM   3550 S SG  . CYS   B 1 160 ? 17.13551  -10.97925 -14.88325 1.000 26.91863 ?  160 CYS   B SG  1 
ATOM   3551 N N   . TYR   B 1 161 ? 15.70149  -9.91314  -18.08723 1.000 20.78484 ?  161 TYR   B N   1 
ATOM   3552 C CA  . TYR   B 1 161 ? 15.83070  -8.54319  -18.56686 1.000 21.35061 ?  161 TYR   B CA  1 
ATOM   3553 C C   . TYR   B 1 161 ? 16.13129  -8.56747  -20.05459 1.000 20.19638 ?  161 TYR   B C   1 
ATOM   3554 O O   . TYR   B 1 161 ? 16.86913  -9.44111  -20.52358 1.000 21.77271 ?  161 TYR   B O   1 
ATOM   3555 C CB  . TYR   B 1 161 ? 16.97065  -7.78889  -17.83710 1.000 23.11552 ?  161 TYR   B CB  1 
ATOM   3556 C CG  . TYR   B 1 161 ? 17.19116  -6.34602  -18.27743 1.000 22.49312 ?  161 TYR   B CG  1 
ATOM   3557 C CD1 . TYR   B 1 161 ? 16.41362  -5.30634  -17.75122 1.000 19.58911 ?  161 TYR   B CD1 1 
ATOM   3558 C CD2 . TYR   B 1 161 ? 18.18884  -6.00953  -19.19523 1.000 20.02363 ?  161 TYR   B CD2 1 
ATOM   3559 C CE1 . TYR   B 1 161 ? 16.61185  -3.96627  -18.15003 1.000 21.29022 ?  161 TYR   B CE1 1 
ATOM   3560 C CE2 . TYR   B 1 161 ? 18.40337  -4.67996  -19.57482 1.000 22.13263 ?  161 TYR   B CE2 1 
ATOM   3561 C CZ  . TYR   B 1 161 ? 17.59108  -3.67449  -19.06399 1.000 21.64403 ?  161 TYR   B CZ  1 
ATOM   3562 O OH  . TYR   B 1 161 ? 17.79731  -2.38005  -19.45541 1.000 22.10729 ?  161 TYR   B OH  1 
ATOM   3563 N N   . MET   B 1 162 ? 15.52215  -7.63765  -20.77350 1.000 21.79946 ?  162 MET   B N   1 
ATOM   3564 C CA  . MET   B 1 162 ? 15.85488  -7.30586  -22.14977 1.000 19.98920 ?  162 MET   B CA  1 
ATOM   3565 C C   . MET   B 1 162 ? 16.00536  -5.79605  -22.24939 1.000 20.18326 ?  162 MET   B C   1 
ATOM   3566 O O   . MET   B 1 162 ? 15.19750  -5.02187  -21.70915 1.000 20.90018 ?  162 MET   B O   1 
ATOM   3567 C CB  . MET   B 1 162 ? 14.78747  -7.81373  -23.17065 1.000 21.56607 ?  162 MET   B CB  1 
ATOM   3568 C CG  . MET   B 1 162 ? 15.26867  -7.53426  -24.56740 1.000 20.92286 ?  162 MET   B CG  1 
ATOM   3569 S SD  . MET   B 1 162 ? 14.17705  -8.29266  -25.80955 1.000 28.23419 ?  162 MET   B SD  1 
ATOM   3570 C CE  . MET   B 1 162 ? 15.06667  -9.81368  -25.94976 1.000 26.64935 ?  162 MET   B CE  1 
ATOM   3571 N N   . HIS   B 1 163 ? 17.06857  -5.36156  -22.90868 1.000 21.33542 ?  163 HIS   B N   1 
ATOM   3572 C CA  . HIS   B 1 163 ? 17.44980  -3.96457  -22.86207 1.000 22.33026 ?  163 HIS   B CA  1 
ATOM   3573 C C   . HIS   B 1 163 ? 16.72736  -3.13259  -23.92566 1.000 23.97748 ?  163 HIS   B C   1 
ATOM   3574 O O   . HIS   B 1 163 ? 16.68672  -3.53888  -25.08766 1.000 24.11158 ?  163 HIS   B O   1 
ATOM   3575 C CB  . HIS   B 1 163 ? 18.93949  -3.83772  -23.08580 1.000 24.17097 ?  163 HIS   B CB  1 
ATOM   3576 C CG  . HIS   B 1 163 ? 19.39321  -2.42649  -23.00658 1.000 21.29830 ?  163 HIS   B CG  1 
ATOM   3577 N ND1 . HIS   B 1 163 ? 19.02878  -1.60204  -21.96473 1.000 22.13600 ?  163 HIS   B ND1 1 
ATOM   3578 C CD2 . HIS   B 1 163 ? 20.11287  -1.66679  -23.86076 1.000 23.09743 ?  163 HIS   B CD2 1 
ATOM   3579 C CE1 . HIS   B 1 163 ? 19.53414  -0.39873  -22.16480 1.000 23.54294 ?  163 HIS   B CE1 1 
ATOM   3580 N NE2 . HIS   B 1 163 ? 20.19934  -0.41301  -23.30594 1.000 23.18452 ?  163 HIS   B NE2 1 
ATOM   3581 N N   . HIS   B 1 164 ? 16.20687  -1.94066  -23.53364 1.000 22.58515 ?  164 HIS   B N   1 
ATOM   3582 C CA  . HIS   B 1 164 ? 15.52925  -1.06635  -24.49495 1.000 22.79484 ?  164 HIS   B CA  1 
ATOM   3583 C C   . HIS   B 1 164 ? 16.00940  0.38349   -24.54301 1.000 25.78759 ?  164 HIS   B C   1 
ATOM   3584 O O   . HIS   B 1 164 ? 15.83419  1.03642   -25.57698 1.000 26.09367 ?  164 HIS   B O   1 
ATOM   3585 C CB  . HIS   B 1 164 ? 14.01081  -0.99712  -24.22768 1.000 23.71609 ?  164 HIS   B CB  1 
ATOM   3586 C CG  . HIS   B 1 164 ? 13.28330  -2.28590  -24.43696 1.000 24.50479 ?  164 HIS   B CG  1 
ATOM   3587 N ND1 . HIS   B 1 164 ? 12.29665  -2.44670  -25.39319 1.000 24.65142 ?  164 HIS   B ND1 1 
ATOM   3588 C CD2 . HIS   B 1 164 ? 13.35667  -3.45983  -23.77051 1.000 23.99540 ?  164 HIS   B CD2 1 
ATOM   3589 C CE1 . HIS   B 1 164 ? 11.81102  -3.67199  -25.31906 1.000 22.20451 ?  164 HIS   B CE1 1 
ATOM   3590 N NE2 . HIS   B 1 164 ? 12.43603  -4.30586  -24.33717 1.000 23.09502 ?  164 HIS   B NE2 1 
ATOM   3591 N N   . MET   B 1 165 ? 16.55282  0.93275   -23.45726 1.000 23.61955 ?  165 MET   B N   1 
ATOM   3592 C CA  . MET   B 1 165 ? 16.65768  2.39541   -23.39510 1.000 25.24569 ?  165 MET   B CA  1 
ATOM   3593 C C   . MET   B 1 165 ? 17.76769  2.84066   -22.45732 1.000 26.83819 ?  165 MET   B C   1 
ATOM   3594 O O   . MET   B 1 165 ? 18.02036  2.20506   -21.43615 1.000 25.13900 ?  165 MET   B O   1 
ATOM   3595 C CB  . MET   B 1 165 ? 15.31497  3.00379   -22.93966 1.000 24.88414 ?  165 MET   B CB  1 
ATOM   3596 C CG  . MET   B 1 165 ? 15.36978  4.45316   -22.59196 1.000 27.51882 ?  165 MET   B CG  1 
ATOM   3597 S SD  . MET   B 1 165 ? 13.73609  5.23389   -22.57632 1.000 32.95178 ?  165 MET   B SD  1 
ATOM   3598 C CE  . MET   B 1 165 ? 12.95537  4.34384   -21.25335 1.000 32.53396 ?  165 MET   B CE  1 
ATOM   3599 N N   . GLU   B 1 166 ? 18.41705  3.95548   -22.81299 1.000 26.33197 ?  166 GLU   B N   1 
ATOM   3600 C CA  . GLU   B 1 166 ? 19.28885  4.70386   -21.91819 1.000 27.89541 ?  166 GLU   B CA  1 
ATOM   3601 C C   . GLU   B 1 166 ? 18.61214  6.02769   -21.58700 1.000 29.27025 ?  166 GLU   B C   1 
ATOM   3602 O O   . GLU   B 1 166 ? 18.24445  6.78503   -22.49881 1.000 29.77321 ?  166 GLU   B O   1 
ATOM   3603 C CB  . GLU   B 1 166 ? 20.65647  4.95749   -22.55118 1.000 30.56613 ?  166 GLU   B CB  1 
ATOM   3604 C CG  . GLU   B 1 166 ? 21.60076  5.68343   -21.61842 1.000 30.47194 ?  166 GLU   B CG  1 
ATOM   3605 C CD  . GLU   B 1 166 ? 23.02149  5.75115   -22.15831 1.000 37.91981 ?  166 GLU   B CD  1 
ATOM   3606 O OE1 . GLU   B 1 166 ? 23.56148  6.86952   -22.26909 1.000 41.07234 ?  166 GLU   B OE1 1 
ATOM   3607 O OE2 . GLU   B 1 166 ? 23.59233  4.68105   -22.47786 1.000 37.87491 -1 166 GLU   B OE2 1 
ATOM   3608 N N   . LEU   B 1 167 ? 18.42388  6.28147   -20.29387 1.000 25.49751 ?  167 LEU   B N   1 
ATOM   3609 C CA  . LEU   B 1 167 ? 17.83031  7.52563   -19.82684 1.000 29.26668 ?  167 LEU   B CA  1 
ATOM   3610 C C   . LEU   B 1 167 ? 18.83074  8.67626   -19.96186 1.000 33.72454 ?  167 LEU   B C   1 
ATOM   3611 O O   . LEU   B 1 167 ? 20.04102  8.45714   -20.08277 1.000 32.16386 ?  167 LEU   B O   1 
ATOM   3612 C CB  . LEU   B 1 167 ? 17.39376  7.39390   -18.37005 1.000 28.74589 ?  167 LEU   B CB  1 
ATOM   3613 C CG  . LEU   B 1 167 ? 16.39554  6.28541   -18.03316 1.000 30.93437 ?  167 LEU   B CG  1 
ATOM   3614 C CD1 . LEU   B 1 167 ? 15.94334  6.43787   -16.58264 1.000 32.25573 ?  167 LEU   B CD1 1 
ATOM   3615 C CD2 . LEU   B 1 167 ? 15.20326  6.26869   -19.01979 1.000 29.74375 ?  167 LEU   B CD2 1 
ATOM   3616 N N   . PRO   B 1 168 ? 18.34144  9.91418   -19.95850 1.000 33.03418 ?  168 PRO   B N   1 
ATOM   3617 C CA  . PRO   B 1 168 ? 19.25563  11.07479  -19.98433 1.000 31.25177 ?  168 PRO   B CA  1 
ATOM   3618 C C   . PRO   B 1 168 ? 20.34154  11.06079  -18.91573 1.000 30.79854 ?  168 PRO   B C   1 
ATOM   3619 O O   . PRO   B 1 168 ? 21.41342  11.64246  -19.13444 1.000 34.08780 ?  168 PRO   B O   1 
ATOM   3620 C CB  . PRO   B 1 168 ? 18.30197  12.25512  -19.78329 1.000 32.52415 ?  168 PRO   B CB  1 
ATOM   3621 C CG  . PRO   B 1 168 ? 17.02675  11.79325  -20.44364 1.000 31.98778 ?  168 PRO   B CG  1 
ATOM   3622 C CD  . PRO   B 1 168 ? 16.93554  10.30212  -20.17555 1.000 32.85118 ?  168 PRO   B CD  1 
ATOM   3623 N N   . THR   B 1 169 ? 20.08862  10.46158  -17.75540 1.000 30.06334 ?  169 THR   B N   1 
ATOM   3624 C CA  . THR   B 1 169 ? 21.07249  10.42197  -16.67771 1.000 30.15950 ?  169 THR   B CA  1 
ATOM   3625 C C   . THR   B 1 169 ? 22.14523  9.36476   -16.88140 1.000 32.48301 ?  169 THR   B C   1 
ATOM   3626 O O   . THR   B 1 169 ? 23.08786  9.29890   -16.07791 1.000 32.85784 ?  169 THR   B O   1 
ATOM   3627 C CB  . THR   B 1 169 ? 20.39739  10.14145  -15.34887 1.000 34.26189 ?  169 THR   B CB  1 
ATOM   3628 O OG1 . THR   B 1 169 ? 19.69306  8.90096   -15.46387 1.000 34.85632 ?  169 THR   B OG1 1 
ATOM   3629 C CG2 . THR   B 1 169 ? 19.43160  11.26113  -14.97540 1.000 34.35594 ?  169 THR   B CG2 1 
ATOM   3630 N N   . GLY   B 1 170 ? 22.01623  8.52964   -17.89696 1.000 31.39995 ?  170 GLY   B N   1 
ATOM   3631 C CA  . GLY   B 1 170 ? 23.00901  7.51864   -18.18956 1.000 30.77081 ?  170 GLY   B CA  1 
ATOM   3632 C C   . GLY   B 1 170 ? 22.67317  6.13050   -17.69334 1.000 31.35363 ?  170 GLY   B C   1 
ATOM   3633 O O   . GLY   B 1 170 ? 23.38855  5.18222   -18.04181 1.000 36.39549 ?  170 GLY   B O   1 
ATOM   3634 N N   . VAL   B 1 171 ? 21.62850  5.97839   -16.88382 1.000 29.18516 ?  171 VAL   B N   1 
ATOM   3635 C CA  . VAL   B 1 171 ? 21.19361  4.65504   -16.44065 1.000 24.81888 ?  171 VAL   B CA  1 
ATOM   3636 C C   . VAL   B 1 171 ? 20.27781  4.06507   -17.51160 1.000 28.00363 ?  171 VAL   B C   1 
ATOM   3637 O O   . VAL   B 1 171 ? 19.98678  4.72505   -18.51817 1.000 27.92963 ?  171 VAL   B O   1 
ATOM   3638 C CB  . VAL   B 1 171 ? 20.51081  4.72669   -15.06254 1.000 25.74706 ?  171 VAL   B CB  1 
ATOM   3639 C CG1 . VAL   B 1 171 ? 21.43000  5.43101   -14.06336 1.000 32.22652 ?  171 VAL   B CG1 1 
ATOM   3640 C CG2 . VAL   B 1 171 ? 19.17334  5.44471   -15.15875 1.000 29.64745 ?  171 VAL   B CG2 1 
ATOM   3641 N N   . HIS   B 1 172 ? 19.82443  2.82778   -17.30697 1.000 25.29321 ?  172 HIS   B N   1 
ATOM   3642 C CA  . HIS   B 1 172 ? 19.22983  2.03509   -18.37212 1.000 23.68772 ?  172 HIS   B CA  1 
ATOM   3643 C C   . HIS   B 1 172 ? 17.89542  1.46167   -17.93776 1.000 25.39995 ?  172 HIS   B C   1 
ATOM   3644 O O   . HIS   B 1 172 ? 17.62659  1.28900   -16.74328 1.000 24.57184 ?  172 HIS   B O   1 
ATOM   3645 C CB  . HIS   B 1 172 ? 20.19477  0.91762   -18.80629 1.000 26.87162 ?  172 HIS   B CB  1 
ATOM   3646 C CG  . HIS   B 1 172 ? 21.45995  1.46515   -19.36680 1.000 26.69930 ?  172 HIS   B CG  1 
ATOM   3647 N ND1 . HIS   B 1 172 ? 22.61210  1.58925   -18.61779 1.000 26.35384 ?  172 HIS   B ND1 1 
ATOM   3648 C CD2 . HIS   B 1 172 ? 21.72749  2.02383   -20.56948 1.000 25.22546 ?  172 HIS   B CD2 1 
ATOM   3649 C CE1 . HIS   B 1 172 ? 23.55092  2.15271   -19.35375 1.000 26.69691 ?  172 HIS   B CE1 1 
ATOM   3650 N NE2 . HIS   B 1 172 ? 23.03810  2.43892   -20.53755 1.000 28.95069 ?  172 HIS   B NE2 1 
ATOM   3651 N N   . ALA   B 1 173 ? 17.04656  1.17995   -18.94211 1.000 22.06952 ?  173 ALA   B N   1 
ATOM   3652 C CA  . ALA   B 1 173 ? 15.69798  0.70686   -18.70540 1.000 23.19285 ?  173 ALA   B CA  1 
ATOM   3653 C C   . ALA   B 1 173 ? 15.34035  -0.37630  -19.72504 1.000 20.49046 ?  173 ALA   B C   1 
ATOM   3654 O O   . ALA   B 1 173 ? 15.79047  -0.35020  -20.87736 1.000 22.79439 ?  173 ALA   B O   1 
ATOM   3655 C CB  . ALA   B 1 173 ? 14.68710  1.87070   -18.79101 1.000 25.28312 ?  173 ALA   B CB  1 
ATOM   3656 N N   . GLY   B 1 174 ? 14.59847  -1.36283  -19.27376 1.000 21.22064 ?  174 GLY   B N   1 
ATOM   3657 C CA  . GLY   B 1 174 ? 14.16125  -2.39865  -20.16963 1.000 21.53228 ?  174 GLY   B CA  1 
ATOM   3658 C C   . GLY   B 1 174 ? 13.01973  -3.17555  -19.58748 1.000 21.05988 ?  174 GLY   B C   1 
ATOM   3659 O O   . GLY   B 1 174 ? 12.38405  -2.75712  -18.61929 1.000 23.30754 ?  174 GLY   B O   1 
ATOM   3660 N N   . THR   B 1 175 ? 12.77036  -4.33113  -20.18306 1.000 21.53188 ?  175 THR   B N   1 
ATOM   3661 C CA  . THR   B 1 175 ? 11.58118  -5.10527  -19.87758 1.000 21.94243 ?  175 THR   B CA  1 
ATOM   3662 C C   . THR   B 1 175 ? 11.96480  -6.49160  -19.38848 1.000 22.64960 ?  175 THR   B C   1 
ATOM   3663 O O   . THR   B 1 175 ? 13.10561  -6.94124  -19.52499 1.000 23.09928 ?  175 THR   B O   1 
ATOM   3664 C CB  . THR   B 1 175 ? 10.66590  -5.23376  -21.11419 1.000 20.04760 ?  175 THR   B CB  1 
ATOM   3665 O OG1 . THR   B 1 175 ? 11.36884  -6.00068  -22.09339 1.000 24.07934 ?  175 THR   B OG1 1 
ATOM   3666 C CG2 . THR   B 1 175 ? 10.31608  -3.84946  -21.71204 1.000 21.34566 ?  175 THR   B CG2 1 
ATOM   3667 N N   . ASP   B 1 176 ? 10.99115  -7.19077  -18.81424 1.000 22.25239 ?  176 ASP   B N   1 
ATOM   3668 C CA  . ASP   B 1 176 ? 11.14446  -8.62491  -18.69282 1.000 22.72424 ?  176 ASP   B CA  1 
ATOM   3669 C C   . ASP   B 1 176 ? 10.89221  -9.26940  -20.06224 1.000 25.62349 ?  176 ASP   B C   1 
ATOM   3670 O O   . ASP   B 1 176 ? 10.67972  -8.57648  -21.06448 1.000 23.14549 ?  176 ASP   B O   1 
ATOM   3671 C CB  . ASP   B 1 176 ? 10.23664  -9.16974  -17.58749 1.000 25.82977 ?  176 ASP   B CB  1 
ATOM   3672 C CG  . ASP   B 1 176 ? 8.74000   -8.96157  -17.85782 1.000 29.09781 ?  176 ASP   B CG  1 
ATOM   3673 O OD1 . ASP   B 1 176 ? 8.31340   -8.85270  -19.04033 1.000 26.20476 ?  176 ASP   B OD1 1 
ATOM   3674 O OD2 . ASP   B 1 176 ? 7.97543   -8.94005  -16.85740 1.000 29.93393 -1 176 ASP   B OD2 1 
ATOM   3675 N N   . LEU   B 1 177 ? 10.94341  -10.59648 -20.11556 1.000 23.01796 ?  177 LEU   B N   1 
ATOM   3676 C CA  . LEU   B 1 177 ? 10.80336  -11.29843 -21.39691 1.000 24.60767 ?  177 LEU   B CA  1 
ATOM   3677 C C   . LEU   B 1 177 ? 9.34395   -11.52515 -21.76898 1.000 29.89034 ?  177 LEU   B C   1 
ATOM   3678 O O   . LEU   B 1 177 ? 9.06540   -12.10061 -22.83332 1.000 28.84128 ?  177 LEU   B O   1 
ATOM   3679 C CB  . LEU   B 1 177 ? 11.56080  -12.63254 -21.38294 1.000 26.12276 ?  177 LEU   B CB  1 
ATOM   3680 C CG  . LEU   B 1 177 ? 13.01761  -12.63934 -21.89187 1.000 27.34467 ?  177 LEU   B CG  1 
ATOM   3681 C CD1 . LEU   B 1 177 ? 13.05619  -12.33708 -23.39910 1.000 31.38664 ?  177 LEU   B CD1 1 
ATOM   3682 C CD2 . LEU   B 1 177 ? 13.84991  -11.64308 -21.13789 1.000 27.52204 ?  177 LEU   B CD2 1 
ATOM   3683 N N   . GLU   B 1 178 ? 8.41055   -11.07021 -20.93315 1.000 26.61498 ?  178 GLU   B N   1 
ATOM   3684 C CA  . GLU   B 1 178 ? 7.03194   -10.85041 -21.35013 1.000 29.03755 ?  178 GLU   B CA  1 
ATOM   3685 C C   . GLU   B 1 178 ? 6.80431   -9.45951  -21.91008 1.000 27.12462 ?  178 GLU   B C   1 
ATOM   3686 O O   . GLU   B 1 178 ? 5.65612   -9.10890  -22.22569 1.000 28.25476 ?  178 GLU   B O   1 
ATOM   3687 C CB  . GLU   B 1 178 ? 6.07869   -11.07919 -20.17403 1.000 30.03002 ?  178 GLU   B CB  1 
ATOM   3688 C CG  . GLU   B 1 178 ? 6.00665   -12.52318 -19.72084 1.000 31.59939 ?  178 GLU   B CG  1 
ATOM   3689 C CD  . GLU   B 1 178 ? 4.92898   -12.73199 -18.66730 1.000 37.88892 ?  178 GLU   B CD  1 
ATOM   3690 O OE1 . GLU   B 1 178 ? 3.99717   -13.50842 -18.92360 1.000 40.16878 ?  178 GLU   B OE1 1 
ATOM   3691 O OE2 . GLU   B 1 178 ? 4.99801   -12.11049 -17.59182 1.000 40.38552 -1 178 GLU   B OE2 1 
ATOM   3692 N N   . GLY   B 1 179 ? 7.84593   -8.63797  -22.01024 1.000 25.15546 ?  179 GLY   B N   1 
ATOM   3693 C CA  . GLY   B 1 179 ? 7.70473   -7.34297  -22.62229 1.000 25.88207 ?  179 GLY   B CA  1 
ATOM   3694 C C   . GLY   B 1 179 ? 7.21002   -6.23400  -21.72561 1.000 24.40985 ?  179 GLY   B C   1 
ATOM   3695 O O   . GLY   B 1 179 ? 6.92466   -5.14562  -22.23086 1.000 25.05211 ?  179 GLY   B O   1 
ATOM   3696 N N   . ASN   B 1 180 ? 7.13747   -6.45327  -20.41513 1.000 24.21555 ?  180 ASN   B N   1 
ATOM   3697 C CA  . ASN   B 1 180 ? 6.67167   -5.43418  -19.48825 1.000 25.79884 ?  180 ASN   B CA  1 
ATOM   3698 C C   . ASN   B 1 180 ? 7.86677   -4.68750  -18.92301 1.000 25.38501 ?  180 ASN   B C   1 
ATOM   3699 O O   . ASN   B 1 180 ? 8.78532   -5.30866  -18.36954 1.000 24.35097 ?  180 ASN   B O   1 
ATOM   3700 C CB  . ASN   B 1 180 ? 5.85851   -6.05822  -18.36077 1.000 25.55849 ?  180 ASN   B CB  1 
ATOM   3701 C CG  . ASN   B 1 180 ? 4.50137   -6.52266  -18.83075 1.000 30.11974 ?  180 ASN   B CG  1 
ATOM   3702 O OD1 . ASN   B 1 180 ? 3.77774   -5.76636  -19.46578 1.000 28.85784 ?  180 ASN   B OD1 1 
ATOM   3703 N ND2 . ASN   B 1 180 ? 4.15333   -7.76469  -18.52795 1.000 32.92046 ?  180 ASN   B ND2 1 
ATOM   3704 N N   . PHE   B 1 181 ? 7.85992   -3.36378  -19.07500 1.000 22.41759 ?  181 PHE   B N   1 
ATOM   3705 C CA  . PHE   B 1 181 ? 8.95828   -2.57254  -18.52583 1.000 23.51665 ?  181 PHE   B CA  1 
ATOM   3706 C C   . PHE   B 1 181 ? 9.07887   -2.78384  -17.02482 1.000 23.96546 ?  181 PHE   B C   1 
ATOM   3707 O O   . PHE   B 1 181 ? 8.07790   -2.94734  -16.31273 1.000 25.98427 ?  181 PHE   B O   1 
ATOM   3708 C CB  . PHE   B 1 181 ? 8.75925   -1.08619  -18.82472 1.000 24.30504 ?  181 PHE   B CB  1 
ATOM   3709 C CG  . PHE   B 1 181 ? 9.48811   -0.61223  -20.04643 1.000 23.55471 ?  181 PHE   B CG  1 
ATOM   3710 C CD1 . PHE   B 1 181 ? 10.81356  -0.19834  -19.96165 1.000 24.81296 ?  181 PHE   B CD1 1 
ATOM   3711 C CD2 . PHE   B 1 181 ? 8.86103   -0.62017  -21.28289 1.000 23.36208 ?  181 PHE   B CD2 1 
ATOM   3712 C CE1 . PHE   B 1 181 ? 11.49423  0.23306   -21.08014 1.000 24.48514 ?  181 PHE   B CE1 1 
ATOM   3713 C CE2 . PHE   B 1 181 ? 9.52632   -0.18484  -22.41886 1.000 27.69016 ?  181 PHE   B CE2 1 
ATOM   3714 C CZ  . PHE   B 1 181 ? 10.84412  0.23157   -22.32710 1.000 27.68586 ?  181 PHE   B CZ  1 
ATOM   3715 N N   . TYR   B 1 182 ? 10.32174  -2.79203  -16.54785 1.000 23.49772 ?  182 TYR   B N   1 
ATOM   3716 C CA  . TYR   B 1 182 ? 10.59871  -2.45498  -15.16411 1.000 23.00972 ?  182 TYR   B CA  1 
ATOM   3717 C C   . TYR   B 1 182 ? 10.48557  -0.94496  -15.01371 1.000 23.03125 ?  182 TYR   B C   1 
ATOM   3718 O O   . TYR   B 1 182 ? 11.16610  -0.19418  -15.71520 1.000 23.63132 ?  182 TYR   B O   1 
ATOM   3719 C CB  . TYR   B 1 182 ? 11.99628  -2.94473  -14.76774 1.000 22.37637 ?  182 TYR   B CB  1 
ATOM   3720 C CG  . TYR   B 1 182 ? 12.12445  -4.45210  -14.75318 1.000 23.55782 ?  182 TYR   B CG  1 
ATOM   3721 C CD1 . TYR   B 1 182 ? 11.70235  -5.18880  -13.64805 1.000 25.33400 ?  182 TYR   B CD1 1 
ATOM   3722 C CD2 . TYR   B 1 182 ? 12.67386  -5.14301  -15.83219 1.000 22.78163 ?  182 TYR   B CD2 1 
ATOM   3723 C CE1 . TYR   B 1 182 ? 11.80570  -6.57317  -13.62344 1.000 24.84873 ?  182 TYR   B CE1 1 
ATOM   3724 C CE2 . TYR   B 1 182 ? 12.78475  -6.51620  -15.82290 1.000 22.79104 ?  182 TYR   B CE2 1 
ATOM   3725 C CZ  . TYR   B 1 182 ? 12.36717  -7.23549  -14.70702 1.000 24.73324 ?  182 TYR   B CZ  1 
ATOM   3726 O OH  . TYR   B 1 182 ? 12.48459  -8.61899  -14.70076 1.000 22.94127 ?  182 TYR   B OH  1 
ATOM   3727 N N   . GLY   B 1 183 ? 9.63042   -0.48786  -14.11649 1.000 24.01864 ?  183 GLY   B N   1 
ATOM   3728 C CA  . GLY   B 1 183 ? 9.55639   0.93255   -13.85413 1.000 21.87037 ?  183 GLY   B CA  1 
ATOM   3729 C C   . GLY   B 1 183 ? 8.61334   1.65229   -14.79398 1.000 27.58894 ?  183 GLY   B C   1 
ATOM   3730 O O   . GLY   B 1 183 ? 8.02574   1.04460   -15.70056 1.000 25.01838 ?  183 GLY   B O   1 
ATOM   3731 N N   . PRO   B 1 184 ? 8.48740   2.97660   -14.60659 1.000 25.69146 ?  184 PRO   B N   1 
ATOM   3732 C CA  . PRO   B 1 184 ? 7.43791   3.76029   -15.29381 1.000 26.06932 ?  184 PRO   B CA  1 
ATOM   3733 C C   . PRO   B 1 184 ? 7.83347   4.27378   -16.67060 1.000 26.54000 ?  184 PRO   B C   1 
ATOM   3734 O O   . PRO   B 1 184 ? 7.41622   5.35977   -17.08720 1.000 27.74109 ?  184 PRO   B O   1 
ATOM   3735 C CB  . PRO   B 1 184 ? 7.21592   4.93435   -14.33008 1.000 28.85436 ?  184 PRO   B CB  1 
ATOM   3736 C CG  . PRO   B 1 184 ? 8.61617   5.17514   -13.77654 1.000 27.35108 ?  184 PRO   B CG  1 
ATOM   3737 C CD  . PRO   B 1 184 ? 9.13008   3.75280   -13.52481 1.000 26.93553 ?  184 PRO   B CD  1 
ATOM   3738 N N   . PHE   B 1 185 ? 8.59312   3.48589   -17.41563 1.000 24.41197 ?  185 PHE   B N   1 
ATOM   3739 C CA  . PHE   B 1 185 ? 9.14070   3.93944   -18.68257 1.000 23.05848 ?  185 PHE   B CA  1 
ATOM   3740 C C   . PHE   B 1 185 ? 8.32932   3.40945   -19.84994 1.000 24.27911 ?  185 PHE   B C   1 
ATOM   3741 O O   . PHE   B 1 185 ? 7.57281   2.45451   -19.71843 1.000 25.63112 ?  185 PHE   B O   1 
ATOM   3742 C CB  . PHE   B 1 185 ? 10.58495  3.49981   -18.80452 1.000 24.54751 ?  185 PHE   B CB  1 
ATOM   3743 C CG  . PHE   B 1 185 ? 11.38841  3.86997   -17.59645 1.000 23.90482 ?  185 PHE   B CG  1 
ATOM   3744 C CD1 . PHE   B 1 185 ? 11.62091  5.20078   -17.30597 1.000 26.48014 ?  185 PHE   B CD1 1 
ATOM   3745 C CD2 . PHE   B 1 185 ? 11.84123  2.90416   -16.72147 1.000 28.17795 ?  185 PHE   B CD2 1 
ATOM   3746 C CE1 . PHE   B 1 185 ? 12.33604  5.55599   -16.17582 1.000 26.84086 ?  185 PHE   B CE1 1 
ATOM   3747 C CE2 . PHE   B 1 185 ? 12.54030  3.25288   -15.59504 1.000 24.40876 ?  185 PHE   B CE2 1 
ATOM   3748 C CZ  . PHE   B 1 185 ? 12.78611  4.58449   -15.32139 1.000 26.45452 ?  185 PHE   B CZ  1 
ATOM   3749 N N   . VAL   B 1 186 ? 8.49979   4.05532   -20.99564 1.000 27.09535 ?  186 VAL   B N   1 
ATOM   3750 C CA  . VAL   B 1 186 ? 7.81767   3.65627   -22.22144 1.000 24.13147 ?  186 VAL   B CA  1 
ATOM   3751 C C   . VAL   B 1 186 ? 8.82178   3.68433   -23.36447 1.000 27.54000 ?  186 VAL   B C   1 
ATOM   3752 O O   . VAL   B 1 186 ? 9.77637   4.47179   -23.35415 1.000 28.50044 ?  186 VAL   B O   1 
ATOM   3753 C CB  . VAL   B 1 186 ? 6.60297   4.57108   -22.52789 1.000 29.06073 ?  186 VAL   B CB  1 
ATOM   3754 C CG1 . VAL   B 1 186 ? 5.52375   4.39960   -21.47137 1.000 28.97267 ?  186 VAL   B CG1 1 
ATOM   3755 C CG2 . VAL   B 1 186 ? 7.03694   5.95884   -22.51534 1.000 30.25764 ?  186 VAL   B CG2 1 
ATOM   3756 N N   . ASP   B 1 187 ? 8.60923   2.80998   -24.35367 1.000 26.58353 ?  187 ASP   B N   1 
ATOM   3757 C CA  . ASP   B 1 187 ? 9.55101   2.68466   -25.46884 1.000 28.57606 ?  187 ASP   B CA  1 
ATOM   3758 C C   . ASP   B 1 187 ? 9.18435   3.69168   -26.56164 1.000 29.30756 ?  187 ASP   B C   1 
ATOM   3759 O O   . ASP   B 1 187 ? 8.72520   3.34624   -27.65376 1.000 30.78698 ?  187 ASP   B O   1 
ATOM   3760 C CB  . ASP   B 1 187 ? 9.62853   1.24484   -25.99363 1.000 25.35374 ?  187 ASP   B CB  1 
ATOM   3761 C CG  . ASP   B 1 187 ? 8.25832   0.55485   -26.22648 1.000 25.25881 ?  187 ASP   B CG  1 
ATOM   3762 O OD1 . ASP   B 1 187 ? 7.20872   0.97249   -25.70231 1.000 28.99954 ?  187 ASP   B OD1 1 
ATOM   3763 O OD2 . ASP   B 1 187 ? 8.24121   -0.49341  -26.90269 1.000 26.70759 -1 187 ASP   B OD2 1 
ATOM   3764 N N   . ARG   B 1 188 ? 9.42176   4.96070   -26.22848 1.000 32.78192 ?  188 ARG   B N   1 
ATOM   3765 C CA  . ARG   B 1 188 ? 9.27289   6.11060   -27.11740 1.000 32.08007 ?  188 ARG   B CA  1 
ATOM   3766 C C   . ARG   B 1 188 ? 10.56426  6.92547   -27.05136 1.000 35.13069 ?  188 ARG   B C   1 
ATOM   3767 O O   . ARG   B 1 188 ? 11.25877  6.92723   -26.03270 1.000 32.67165 ?  188 ARG   B O   1 
ATOM   3768 C CB  . ARG   B 1 188 ? 8.02523   6.98915   -26.70671 1.000 35.05967 ?  188 ARG   B CB  1 
ATOM   3769 C CG  . ARG   B 1 188 ? 8.23044   7.80449   -25.37993 1.000 38.25822 ?  188 ARG   B CG  1 
ATOM   3770 C CD  . ARG   B 1 188 ? 6.96758   8.48734   -24.67253 1.000 43.88278 ?  188 ARG   B CD  1 
ATOM   3771 N NE  . ARG   B 1 188 ? 7.25951   9.73912   -23.94527 1.000 45.64163 ?  188 ARG   B NE  1 
ATOM   3772 C CZ  . ARG   B 1 188 ? 7.32356   9.92929   -22.62143 1.000 28.68417 ?  188 ARG   B CZ  1 
ATOM   3773 N NH1 . ARG   B 1 188 ? 7.19819   8.94017   -21.75795 1.000 34.61515 ?  188 ARG   B NH1 1 
ATOM   3774 N NH2 . ARG   B 1 188 ? 7.48449   11.15038  -22.15613 1.000 23.08853 ?  188 ARG   B NH2 1 
ATOM   3775 N N   . GLN   B 1 189 ? 10.90391  7.61358   -28.14247 1.000 30.21491 ?  189 GLN   B N   1 
ATOM   3776 C CA  . GLN   B 1 189 ? 12.14450  8.38742   -28.19348 1.000 34.13093 ?  189 GLN   B CA  1 
ATOM   3777 C C   . GLN   B 1 189 ? 11.90488  9.75404   -27.54319 1.000 36.76626 ?  189 GLN   B C   1 
ATOM   3778 O O   . GLN   B 1 189 ? 11.78279  10.79201  -28.20059 1.000 37.38586 ?  189 GLN   B O   1 
ATOM   3779 C CB  . GLN   B 1 189 ? 12.64416  8.49490   -29.62770 1.000 34.52287 ?  189 GLN   B CB  1 
ATOM   3780 C CG  . GLN   B 1 189 ? 13.98385  9.18525   -29.80462 1.000 40.90208 ?  189 GLN   B CG  1 
ATOM   3781 C CD  . GLN   B 1 189 ? 15.17937  8.31785   -29.40724 1.000 40.07007 ?  189 GLN   B CD  1 
ATOM   3782 O OE1 . GLN   B 1 189 ? 15.03516  7.29349   -28.74132 1.000 35.24392 ?  189 GLN   B OE1 1 
ATOM   3783 N NE2 . GLN   B 1 189 ? 16.37166  8.74264   -29.81785 1.000 41.12831 ?  189 GLN   B NE2 1 
ATOM   3784 N N   . THR   B 1 190 ? 11.79796  9.72667   -26.20977 1.000 32.09099 ?  190 THR   B N   1 
ATOM   3785 C CA  . THR   B 1 190 ? 11.58532  10.91755  -25.39317 1.000 33.62804 ?  190 THR   B CA  1 
ATOM   3786 C C   . THR   B 1 190 ? 12.41756  10.82863  -24.12072 1.000 33.73537 ?  190 THR   B C   1 
ATOM   3787 O O   . THR   B 1 190 ? 12.74525  9.73845   -23.64166 1.000 34.89469 ?  190 THR   B O   1 
ATOM   3788 C CB  . THR   B 1 190 ? 10.11933  11.09691  -24.99507 1.000 36.22067 ?  190 THR   B CB  1 
ATOM   3789 O OG1 . THR   B 1 190 ? 9.75152   10.00674  -24.14330 1.000 41.77739 ?  190 THR   B OG1 1 
ATOM   3790 C CG2 . THR   B 1 190 ? 9.21854   11.09780  -26.21576 1.000 40.17481 ?  190 THR   B CG2 1 
ATOM   3791 N N   . ALA   B 1 191 ? 12.73581  11.99128  -23.55495 1.000 32.41760 ?  191 ALA   B N   1 
ATOM   3792 C CA  . ALA   B 1 191 ? 13.53503  12.04366  -22.33525 1.000 31.41839 ?  191 ALA   B CA  1 
ATOM   3793 C C   . ALA   B 1 191 ? 12.66870  11.70170  -21.13281 1.000 35.10369 ?  191 ALA   B C   1 
ATOM   3794 O O   . ALA   B 1 191 ? 11.63227  12.33375  -20.89814 1.000 34.83630 ?  191 ALA   B O   1 
ATOM   3795 C CB  . ALA   B 1 191 ? 14.16169  13.42445  -22.15285 1.000 33.82701 ?  191 ALA   B CB  1 
ATOM   3796 N N   . GLN   B 1 192 ? 13.08465  10.69260  -20.37407 1.000 29.06919 ?  192 GLN   B N   1 
ATOM   3797 C CA  . GLN   B 1 192 ? 12.30197  10.20984  -19.25069 1.000 28.17378 ?  192 GLN   B CA  1 
ATOM   3798 C C   . GLN   B 1 192 ? 13.16368  10.14545  -18.00552 1.000 30.41059 ?  192 GLN   B C   1 
ATOM   3799 O O   . GLN   B 1 192 ? 14.32177  9.71357   -18.05541 1.000 32.38125 ?  192 GLN   B O   1 
ATOM   3800 C CB  . GLN   B 1 192 ? 11.71595  8.83474   -19.55165 1.000 28.14187 ?  192 GLN   B CB  1 
ATOM   3801 C CG  . GLN   B 1 192 ? 10.81630  8.86020   -20.79817 1.000 30.32125 ?  192 GLN   B CG  1 
ATOM   3802 C CD  . GLN   B 1 192 ? 10.46332  7.48047   -21.27532 1.000 27.60503 ?  192 GLN   B CD  1 
ATOM   3803 O OE1 . GLN   B 1 192 ? 9.99520   6.66049   -20.49854 1.000 26.41849 ?  192 GLN   B OE1 1 
ATOM   3804 N NE2 . GLN   B 1 192 ? 10.71180  7.20120   -22.55803 1.000 30.01751 ?  192 GLN   B NE2 1 
ATOM   3805 N N   . ALA   B 1 193 ? 12.59412  10.58816  -16.89362 1.000 29.45561 ?  193 ALA   B N   1 
ATOM   3806 C CA  . ALA   B 1 193 ? 13.25677  10.55883  -15.59910 1.000 30.01784 ?  193 ALA   B CA  1 
ATOM   3807 C C   . ALA   B 1 193 ? 12.74342  9.38153   -14.78735 1.000 32.07620 ?  193 ALA   B C   1 
ATOM   3808 O O   . ALA   B 1 193 ? 11.59265  8.96059   -14.92901 1.000 28.91978 ?  193 ALA   B O   1 
ATOM   3809 C CB  . ALA   B 1 193 ? 13.01330  11.85973  -14.82779 1.000 32.88170 ?  193 ALA   B CB  1 
ATOM   3810 N N   . ALA   B 1 194 ? 13.62092  8.82712   -13.95095 1.000 29.59011 ?  194 ALA   B N   1 
ATOM   3811 C CA  . ALA   B 1 194 ? 13.22661  7.79474   -13.01263 1.000 29.47092 ?  194 ALA   B CA  1 
ATOM   3812 C C   . ALA   B 1 194 ? 12.80915  8.42950   -11.69488 1.000 30.28081 ?  194 ALA   B C   1 
ATOM   3813 O O   . ALA   B 1 194 ? 13.08581  9.59987   -11.43130 1.000 32.88907 ?  194 ALA   B O   1 
ATOM   3814 C CB  . ALA   B 1 194 ? 14.38449  6.81244   -12.77623 1.000 29.05299 ?  194 ALA   B CB  1 
ATOM   3815 N N   . GLY   B 1 195 ? 12.14320  7.63845   -10.85907 1.000 30.56383 ?  195 GLY   B N   1 
ATOM   3816 C CA  . GLY   B 1 195 ? 11.95501  8.02679   -9.47321  1.000 32.72552 ?  195 GLY   B CA  1 
ATOM   3817 C C   . GLY   B 1 195 ? 13.28223  8.13312   -8.74879  1.000 34.35327 ?  195 GLY   B C   1 
ATOM   3818 O O   . GLY   B 1 195 ? 14.30978  7.63849   -9.20965  1.000 31.10463 ?  195 GLY   B O   1 
ATOM   3819 N N   . THR   B 1 196 ? 13.27239  8.81249   -7.60686  1.000 36.78803 ?  196 THR   B N   1 
ATOM   3820 C CA  . THR   B 1 196 ? 14.51572  8.97999   -6.86612  1.000 37.12417 ?  196 THR   B CA  1 
ATOM   3821 C C   . THR   B 1 196 ? 15.06344  7.62130   -6.45455  1.000 34.56988 ?  196 THR   B C   1 
ATOM   3822 O O   . THR   B 1 196 ? 14.33266  6.75337   -5.97330  1.000 35.80297 ?  196 THR   B O   1 
ATOM   3823 C CB  . THR   B 1 196 ? 14.30257  9.87278   -5.64232  1.000 45.49389 ?  196 THR   B CB  1 
ATOM   3824 O OG1 . THR   B 1 196 ? 13.30615  9.29451   -4.78928  1.000 46.59688 ?  196 THR   B OG1 1 
ATOM   3825 C CG2 . THR   B 1 196 ? 13.85351  11.26077  -6.08731  1.000 38.14773 ?  196 THR   B CG2 1 
ATOM   3826 N N   . ASP   B 1 197 ? 16.34207  7.40637   -6.69324  1.000 31.31178 ?  197 ASP   B N   1 
ATOM   3827 C CA  . ASP   B 1 197 ? 16.84832  6.08864   -6.37914  1.000 31.64575 ?  197 ASP   B CA  1 
ATOM   3828 C C   . ASP   B 1 197 ? 17.20599  6.03039   -4.90785  1.000 31.56420 ?  197 ASP   B C   1 
ATOM   3829 O O   . ASP   B 1 197 ? 17.47657  7.05549   -4.27101  1.000 37.92018 ?  197 ASP   B O   1 
ATOM   3830 C CB  . ASP   B 1 197 ? 18.05872  5.72475   -7.21348  1.000 33.29105 ?  197 ASP   B CB  1 
ATOM   3831 C CG  . ASP   B 1 197 ? 18.25522  4.20663   -7.32327  1.000 30.85344 ?  197 ASP   B CG  1 
ATOM   3832 O OD1 . ASP   B 1 197 ? 17.32834  3.37524   -7.00121  1.000 29.94662 ?  197 ASP   B OD1 1 
ATOM   3833 O OD2 . ASP   B 1 197 ? 19.35641  3.85488   -7.76222  1.000 30.89131 ?  197 ASP   B OD2 1 
ATOM   3834 N N   . THR   B 1 198 ? 17.12490  4.83097   -4.36019  1.000 26.92803 ?  198 THR   B N   1 
ATOM   3835 C CA  . THR   B 1 198 ? 17.51312  4.55672   -2.98672  1.000 24.97320 ?  198 THR   B CA  1 
ATOM   3836 C C   . THR   B 1 198 ? 18.59149  3.48548   -3.01156  1.000 31.03069 ?  198 THR   B C   1 
ATOM   3837 O O   . THR   B 1 198 ? 18.79800  2.80668   -4.02198  1.000 28.97922 ?  198 THR   B O   1 
ATOM   3838 C CB  . THR   B 1 198 ? 16.31031  4.09349   -2.15341  1.000 28.75049 ?  198 THR   B CB  1 
ATOM   3839 O OG1 . THR   B 1 198 ? 15.62439  3.04530   -2.85481  1.000 31.95729 ?  198 THR   B OG1 1 
ATOM   3840 C CG2 . THR   B 1 198 ? 15.34042  5.25726   -1.94349  1.000 32.06633 ?  198 THR   B CG2 1 
ATOM   3841 N N   . THR   B 1 199 ? 19.27471  3.34242   -1.88604  1.000 27.41974 ?  199 THR   B N   1 
ATOM   3842 C CA  . THR   B 1 199 ? 20.32307  2.34182   -1.74078  1.000 25.58660 ?  199 THR   B CA  1 
ATOM   3843 C C   . THR   B 1 199 ? 19.76350  1.03209   -1.18470  1.000 23.84912 ?  199 THR   B C   1 
ATOM   3844 O O   . THR   B 1 199 ? 18.88024  1.02831   -0.31388  1.000 24.10481 ?  199 THR   B O   1 
ATOM   3845 C CB  . THR   B 1 199 ? 21.42937  2.89553   -0.84261  1.000 27.56156 ?  199 THR   B CB  1 
ATOM   3846 O OG1 . THR   B 1 199 ? 21.94678  4.10817   -1.42716  1.000 31.59267 ?  199 THR   B OG1 1 
ATOM   3847 C CG2 . THR   B 1 199 ? 22.55667  1.88799   -0.71404  1.000 27.47432 ?  199 THR   B CG2 1 
ATOM   3848 N N   . ILE   B 1 200 ? 20.27445  -0.09137  -1.70056  1.000 23.20190 ?  200 ILE   B N   1 
ATOM   3849 C CA  . ILE   B 1 200 ? 19.75318  -1.41061  -1.34434  1.000 23.70575 ?  200 ILE   B CA  1 
ATOM   3850 C C   . ILE   B 1 200 ? 20.45770  -1.84509  -0.05975  1.000 24.32656 ?  200 ILE   B C   1 
ATOM   3851 O O   . ILE   B 1 200 ? 21.53835  -2.42676  -0.11172  1.000 23.73067 ?  200 ILE   B O   1 
ATOM   3852 C CB  . ILE   B 1 200 ? 19.96529  -2.44271  -2.45731  1.000 23.58598 ?  200 ILE   B CB  1 
ATOM   3853 C CG1 . ILE   B 1 200 ? 19.32950  -1.97395  -3.78303  1.000 23.06882 ?  200 ILE   B CG1 1 
ATOM   3854 C CG2 . ILE   B 1 200 ? 19.31746  -3.73842  -2.06767  1.000 25.33048 ?  200 ILE   B CG2 1 
ATOM   3855 C CD1 . ILE   B 1 200 ? 19.97515  -2.61210  -5.06691  1.000 25.72468 ?  200 ILE   B CD1 1 
ATOM   3856 N N   . THR   B 1 201 ? 19.80761  -1.59748  1.09061   1.000 23.16129 ?  201 THR   B N   1 
ATOM   3857 C CA  . THR   B 1 201 ? 20.45095  -1.74773  2.40799   1.000 21.31453 ?  201 THR   B CA  1 
ATOM   3858 C C   . THR   B 1 201 ? 20.88934  -3.18477  2.70288   1.000 20.80554 ?  201 THR   B C   1 
ATOM   3859 O O   . THR   B 1 201 ? 21.97656  -3.40849  3.25459   1.000 22.08471 ?  201 THR   B O   1 
ATOM   3860 C CB  . THR   B 1 201 ? 19.47444  -1.27490  3.47048   1.000 24.39378 ?  201 THR   B CB  1 
ATOM   3861 O OG1 . THR   B 1 201 ? 19.02784  0.03679   3.09728   1.000 25.62848 ?  201 THR   B OG1 1 
ATOM   3862 C CG2 . THR   B 1 201 ? 20.16060  -1.19327  4.84975   1.000 22.93349 ?  201 THR   B CG2 1 
ATOM   3863 N N   . VAL   B 1 202 ? 20.03587  -4.16574  2.42522   1.000 22.85615 ?  202 VAL   B N   1 
ATOM   3864 C CA  . VAL   B 1 202 ? 20.42676  -5.54201  2.72871   1.000 22.75150 ?  202 VAL   B CA  1 
ATOM   3865 C C   . VAL   B 1 202 ? 21.68699  -5.91352  1.95940   1.000 24.33438 ?  202 VAL   B C   1 
ATOM   3866 O O   . VAL   B 1 202 ? 22.54330  -6.65478  2.47072   1.000 22.96026 ?  202 VAL   B O   1 
ATOM   3867 C CB  . VAL   B 1 202 ? 19.25884  -6.52491  2.46107   1.000 25.91348 ?  202 VAL   B CB  1 
ATOM   3868 C CG1 . VAL   B 1 202 ? 18.82586  -6.55828  0.95802   1.000 27.54516 ?  202 VAL   B CG1 1 
ATOM   3869 C CG2 . VAL   B 1 202 ? 19.61333  -7.92789  2.99414   1.000 25.98675 ?  202 VAL   B CG2 1 
ATOM   3870 N N   . ASN   B 1 203 ? 21.85336  -5.36315  0.74580   1.000 23.21480 ?  203 ASN   B N   1 
ATOM   3871 C CA  . ASN   B 1 203 ? 23.05686  -5.64506  -0.03852  1.000 23.61786 ?  203 ASN   B CA  1 
ATOM   3872 C C   . ASN   B 1 203 ? 24.27849  -4.94232  0.54533   1.000 25.44226 ?  203 ASN   B C   1 
ATOM   3873 O O   . ASN   B 1 203 ? 25.38637  -5.49855  0.55340   1.000 23.47426 ?  203 ASN   B O   1 
ATOM   3874 C CB  . ASN   B 1 203 ? 22.84288  -5.23326  -1.49683  1.000 23.58418 ?  203 ASN   B CB  1 
ATOM   3875 C CG  . ASN   B 1 203 ? 21.85151  -6.14373  -2.21943  1.000 23.73699 ?  203 ASN   B CG  1 
ATOM   3876 O OD1 . ASN   B 1 203 ? 21.30523  -7.08088  -1.64844  1.000 23.26636 ?  203 ASN   B OD1 1 
ATOM   3877 N ND2 . ASN   B 1 203 ? 21.60311  -5.84249  -3.47404  1.000 24.62513 ?  203 ASN   B ND2 1 
ATOM   3878 N N   . VAL   B 1 204 ? 24.10514  -3.71590  1.04259   1.000 20.59194 ?  204 VAL   B N   1 
ATOM   3879 C CA  . VAL   B 1 204 ? 25.23328  -3.04498  1.68311   1.000 22.70902 ?  204 VAL   B CA  1 
ATOM   3880 C C   . VAL   B 1 204 ? 25.70409  -3.86089  2.87538   1.000 22.46113 ?  204 VAL   B C   1 
ATOM   3881 O O   . VAL   B 1 204 ? 26.91005  -4.05525  3.06949   1.000 24.06793 ?  204 VAL   B O   1 
ATOM   3882 C CB  . VAL   B 1 204 ? 24.86337  -1.60440  2.09668   1.000 20.27569 ?  204 VAL   B CB  1 
ATOM   3883 C CG1 . VAL   B 1 204 ? 26.03432  -0.93937  2.83053   1.000 23.67221 ?  204 VAL   B CG1 1 
ATOM   3884 C CG2 . VAL   B 1 204 ? 24.52629  -0.77445  0.87993   1.000 25.77029 ?  204 VAL   B CG2 1 
ATOM   3885 N N   . LEU   B 1 205 ? 24.76180  -4.38777  3.67185   1.000 21.12275 ?  205 LEU   B N   1 
ATOM   3886 C CA  . LEU   B 1 205 ? 25.16152  -5.17362  4.83909   1.000 21.81772 ?  205 LEU   B CA  1 
ATOM   3887 C C   . LEU   B 1 205 ? 25.86354  -6.45657  4.41272   1.000 23.88540 ?  205 LEU   B C   1 
ATOM   3888 O O   . LEU   B 1 205 ? 26.87033  -6.85856  5.01471   1.000 25.04591 ?  205 LEU   B O   1 
ATOM   3889 C CB  . LEU   B 1 205 ? 23.94740  -5.50202  5.70051   1.000 20.89272 ?  205 LEU   B CB  1 
ATOM   3890 C CG  . LEU   B 1 205 ? 23.32198  -4.26125  6.33612   1.000 22.17032 ?  205 LEU   B CG  1 
ATOM   3891 C CD1 . LEU   B 1 205 ? 21.97009  -4.61455  6.89573   1.000 23.89620 ?  205 LEU   B CD1 1 
ATOM   3892 C CD2 . LEU   B 1 205 ? 24.23839  -3.77351  7.48186   1.000 21.51925 ?  205 LEU   B CD2 1 
ATOM   3893 N N   . ALA   B 1 206 ? 25.36634  -7.09088  3.35089   1.000 22.11666 ?  206 ALA   B N   1 
ATOM   3894 C CA  . ALA   B 1 206 ? 26.03606  -8.29186  2.85033   1.000 27.14862 ?  206 ALA   B CA  1 
ATOM   3895 C C   . ALA   B 1 206 ? 27.48197  -7.99936  2.45891   1.000 24.81846 ?  206 ALA   B C   1 
ATOM   3896 O O   . ALA   B 1 206 ? 28.39674  -8.80135  2.73480   1.000 25.02009 ?  206 ALA   B O   1 
ATOM   3897 C CB  . ALA   B 1 206 ? 25.26026  -8.83385  1.65664   1.000 22.96178 ?  206 ALA   B CB  1 
ATOM   3898 N N   . TRP   B 1 207 ? 27.69589  -6.85859  1.79647   1.000 23.00704 ?  207 TRP   B N   1 
ATOM   3899 C CA  . TRP   B 1 207 ? 29.01847  -6.44771  1.34676   1.000 24.88426 ?  207 TRP   B CA  1 
ATOM   3900 C C   . TRP   B 1 207 ? 29.92251  -6.10405  2.52222   1.000 25.71353 ?  207 TRP   B C   1 
ATOM   3901 O O   . TRP   B 1 207 ? 31.12190  -6.39398  2.48491   1.000 27.14242 ?  207 TRP   B O   1 
ATOM   3902 C CB  . TRP   B 1 207 ? 28.87297  -5.27064  0.39520   1.000 26.64744 ?  207 TRP   B CB  1 
ATOM   3903 C CG  . TRP   B 1 207 ? 30.10330  -4.64927  -0.10859  1.000 27.49339 ?  207 TRP   B CG  1 
ATOM   3904 C CD1 . TRP   B 1 207 ? 30.94707  -5.14565  -1.07561  1.000 29.48645 ?  207 TRP   B CD1 1 
ATOM   3905 C CD2 . TRP   B 1 207 ? 30.61779  -3.37257  0.25717   1.000 28.24990 ?  207 TRP   B CD2 1 
ATOM   3906 N NE1 . TRP   B 1 207 ? 31.95201  -4.24975  -1.31588  1.000 29.59499 ?  207 TRP   B NE1 1 
ATOM   3907 C CE2 . TRP   B 1 207 ? 31.78263  -3.15867  -0.50713  1.000 27.81974 ?  207 TRP   B CE2 1 
ATOM   3908 C CE3 . TRP   B 1 207 ? 30.21825  -2.39239  1.17386   1.000 26.24526 ?  207 TRP   B CE3 1 
ATOM   3909 C CZ2 . TRP   B 1 207 ? 32.54269  -2.00920  -0.39295  1.000 31.87075 ?  207 TRP   B CZ2 1 
ATOM   3910 C CZ3 . TRP   B 1 207 ? 30.98365  -1.24000  1.28395   1.000 30.07207 ?  207 TRP   B CZ3 1 
ATOM   3911 C CH2 . TRP   B 1 207 ? 32.12828  -1.06288  0.50416   1.000 28.51841 ?  207 TRP   B CH2 1 
ATOM   3912 N N   . LEU   B 1 208 ? 29.36194  -5.50050  3.58266   1.000 24.35003 ?  208 LEU   B N   1 
ATOM   3913 C CA  . LEU   B 1 208 ? 30.15348  -5.27941  4.79732   1.000 22.73787 ?  208 LEU   B CA  1 
ATOM   3914 C C   . LEU   B 1 208 ? 30.58463  -6.59779  5.41940   1.000 27.17868 ?  208 LEU   B C   1 
ATOM   3915 O O   . LEU   B 1 208 ? 31.70880  -6.71420  5.92621   1.000 30.42470 ?  208 LEU   B O   1 
ATOM   3916 C CB  . LEU   B 1 208 ? 29.35970  -4.43640  5.80731   1.000 23.73166 ?  208 LEU   B CB  1 
ATOM   3917 C CG  . LEU   B 1 208 ? 29.11977  -2.99231  5.35975   1.000 26.14969 ?  208 LEU   B CG  1 
ATOM   3918 C CD1 . LEU   B 1 208 ? 28.26918  -2.20134  6.36910   1.000 26.01537 ?  208 LEU   B CD1 1 
ATOM   3919 C CD2 . LEU   B 1 208 ? 30.44054  -2.26333  5.07913   1.000 26.31910 ?  208 LEU   B CD2 1 
ATOM   3920 N N   . TYR   B 1 209 ? 29.71134  -7.60946  5.39235   1.000 25.75008 ?  209 TYR   B N   1 
ATOM   3921 C CA  . TYR   B 1 209 ? 30.12938  -8.92619  5.87021   1.000 27.71582 ?  209 TYR   B CA  1 
ATOM   3922 C C   . TYR   B 1 209 ? 31.24170  -9.50150  5.00166   1.000 32.63778 ?  209 TYR   B C   1 
ATOM   3923 O O   . TYR   B 1 209 ? 32.20054  -10.09469 5.51551   1.000 29.39545 ?  209 TYR   B O   1 
ATOM   3924 C CB  . TYR   B 1 209 ? 28.95543  -9.88598  5.90551   1.000 25.81436 ?  209 TYR   B CB  1 
ATOM   3925 C CG  . TYR   B 1 209 ? 28.10458  -9.75854  7.12897   1.000 28.43625 ?  209 TYR   B CG  1 
ATOM   3926 C CD1 . TYR   B 1 209 ? 28.56849  -10.22978 8.36104   1.000 29.43780 ?  209 TYR   B CD1 1 
ATOM   3927 C CD2 . TYR   B 1 209 ? 26.83638  -9.19322  7.06806   1.000 28.29978 ?  209 TYR   B CD2 1 
ATOM   3928 C CE1 . TYR   B 1 209 ? 27.79270  -10.14072 9.49944   1.000 30.79293 ?  209 TYR   B CE1 1 
ATOM   3929 C CE2 . TYR   B 1 209 ? 26.03945  -9.09811  8.20425   1.000 27.17890 ?  209 TYR   B CE2 1 
ATOM   3930 C CZ  . TYR   B 1 209 ? 26.54387  -9.56656  9.42657   1.000 33.10777 ?  209 TYR   B CZ  1 
ATOM   3931 O OH  . TYR   B 1 209 ? 25.78947  -9.49502  10.57183  1.000 30.86421 ?  209 TYR   B OH  1 
ATOM   3932 N N   . ALA   B 1 210 ? 31.11335  -9.36571  3.68147   1.000 28.08150 ?  210 ALA   B N   1 
ATOM   3933 C CA  . ALA   B 1 210 ? 32.19908  -9.76040  2.78140   1.000 29.29662 ?  210 ALA   B CA  1 
ATOM   3934 C C   . ALA   B 1 210 ? 33.50755  -9.06358  3.14291   1.000 33.14816 ?  210 ALA   B C   1 
ATOM   3935 O O   . ALA   B 1 210 ? 34.58416  -9.67771  3.09233   1.000 32.73957 ?  210 ALA   B O   1 
ATOM   3936 C CB  . ALA   B 1 210 ? 31.82457  -9.45500  1.32622   1.000 31.75681 ?  210 ALA   B CB  1 
ATOM   3937 N N   . ALA   B 1 211 ? 33.44152  -7.77183  3.46313   1.000 27.19377 ?  211 ALA   B N   1 
ATOM   3938 C CA  . ALA   B 1 211 ? 34.65017  -7.03847  3.82786   1.000 31.80635 ?  211 ALA   B CA  1 
ATOM   3939 C C   . ALA   B 1 211 ? 35.26733  -7.60512  5.09664   1.000 35.30114 ?  211 ALA   B C   1 
ATOM   3940 O O   . ALA   B 1 211 ? 36.49783  -7.69617  5.20645   1.000 34.84122 ?  211 ALA   B O   1 
ATOM   3941 C CB  . ALA   B 1 211 ? 34.35808  -5.54754  4.01737   1.000 28.28815 ?  211 ALA   B CB  1 
ATOM   3942 N N   . VAL   B 1 212 ? 34.43278  -7.97573  6.07422   1.000 30.49655 ?  212 VAL   B N   1 
ATOM   3943 C CA  . VAL   B 1 212 ? 34.98842  -8.56835  7.29520   1.000 34.45847 ?  212 VAL   B CA  1 
ATOM   3944 C C   . VAL   B 1 212 ? 35.60311  -9.93385  6.98966   1.000 35.69419 ?  212 VAL   B C   1 
ATOM   3945 O O   . VAL   B 1 212 ? 36.69264  -10.26922 7.48264   1.000 38.71137 ?  212 VAL   B O   1 
ATOM   3946 C CB  . VAL   B 1 212 ? 33.91770  -8.66393  8.40311   1.000 31.86712 ?  212 VAL   B CB  1 
ATOM   3947 C CG1 . VAL   B 1 212 ? 34.42343  -9.51027  9.58237   1.000 36.02566 ?  212 VAL   B CG1 1 
ATOM   3948 C CG2 . VAL   B 1 212 ? 33.52499  -7.30240  8.88479   1.000 29.66976 ?  212 VAL   B CG2 1 
ATOM   3949 N N   . ILE   B 1 213 ? 34.92224  -10.73920 6.17384   1.000 33.82804 ?  213 ILE   B N   1 
ATOM   3950 C CA  . ILE   B 1 213 ? 35.43476  -12.05800 5.80188   1.000 36.35268 ?  213 ILE   B CA  1 
ATOM   3951 C C   . ILE   B 1 213 ? 36.78875  -11.93386 5.11303   1.000 35.31237 ?  213 ILE   B C   1 
ATOM   3952 O O   . ILE   B 1 213 ? 37.64942  -12.81357 5.25280   1.000 40.46638 ?  213 ILE   B O   1 
ATOM   3953 C CB  . ILE   B 1 213 ? 34.40581  -12.80020 4.92660   1.000 36.90650 ?  213 ILE   B CB  1 
ATOM   3954 C CG1 . ILE   B 1 213 ? 33.15619  -13.13997 5.74441   1.000 35.95942 ?  213 ILE   B CG1 1 
ATOM   3955 C CG2 . ILE   B 1 213 ? 35.00979  -14.07706 4.33416   1.000 39.31566 ?  213 ILE   B CG2 1 
ATOM   3956 C CD1 . ILE   B 1 213 ? 32.02250  -13.79208 4.93635   1.000 37.53266 ?  213 ILE   B CD1 1 
ATOM   3957 N N   . ASN   B 1 214 ? 37.03420  -10.82429 4.42301   1.000 34.69293 ?  214 ASN   B N   1 
ATOM   3958 C CA  . ASN   B 1 214 ? 38.30654  -10.63377 3.74865   1.000 37.47195 ?  214 ASN   B CA  1 
ATOM   3959 C C   . ASN   B 1 214 ? 39.28857  -9.77341  4.53332   1.000 40.94223 ?  214 ASN   B C   1 
ATOM   3960 O O   . ASN   B 1 214 ? 40.31820  -9.37466  3.97821   1.000 42.37486 ?  214 ASN   B O   1 
ATOM   3961 C CB  . ASN   B 1 214 ? 38.07402  -10.07368 2.35390   1.000 36.95644 ?  214 ASN   B CB  1 
ATOM   3962 C CG  . ASN   B 1 214 ? 37.63261  -11.15894 1.39078   1.000 41.72094 ?  214 ASN   B CG  1 
ATOM   3963 O OD1 . ASN   B 1 214 ? 38.46807  -11.84609 0.79522   1.000 42.43162 ?  214 ASN   B OD1 1 
ATOM   3964 N ND2 . ASN   B 1 214 ? 36.31761  -11.36777 1.28408   1.000 39.57036 ?  214 ASN   B ND2 1 
ATOM   3965 N N   . GLY   B 1 215 ? 39.00900  -9.49741  5.80797   1.000 38.25995 ?  215 GLY   B N   1 
ATOM   3966 C CA  . GLY   B 1 215 ? 39.96685  -8.86180  6.69281   1.000 40.62173 ?  215 GLY   B CA  1 
ATOM   3967 C C   . GLY   B 1 215 ? 39.84099  -7.36108  6.84074   1.000 44.95029 ?  215 GLY   B C   1 
ATOM   3968 O O   . GLY   B 1 215 ? 40.70929  -6.74260  7.47115   1.000 43.81522 ?  215 GLY   B O   1 
ATOM   3969 N N   . ASP   B 1 216 ? 38.80261  -6.75450  6.27529   1.000 38.52307 ?  216 ASP   B N   1 
ATOM   3970 C CA  . ASP   B 1 216 ? 38.56779  -5.32125  6.38866   1.000 38.68354 ?  216 ASP   B CA  1 
ATOM   3971 C C   . ASP   B 1 216 ? 37.60309  -5.12103  7.55464   1.000 43.78155 ?  216 ASP   B C   1 
ATOM   3972 O O   . ASP   B 1 216 ? 36.45265  -5.56644  7.49166   1.000 42.70661 ?  216 ASP   B O   1 
ATOM   3973 C CB  . ASP   B 1 216 ? 37.98970  -4.78032  5.08127   1.000 44.37124 ?  216 ASP   B CB  1 
ATOM   3974 C CG  . ASP   B 1 216 ? 38.91864  -3.80387  4.37228   1.000 49.75510 ?  216 ASP   B CG  1 
ATOM   3975 O OD1 . ASP   B 1 216 ? 39.77841  -3.19124  5.04469   1.000 52.79870 ?  216 ASP   B OD1 1 
ATOM   3976 O OD2 . ASP   B 1 216 ? 38.76417  -3.62909  3.13186   1.000 48.21483 -1 216 ASP   B OD2 1 
ATOM   3977 N N   . ARG   B 1 217 ? 38.07072  -4.47727  8.63460   1.000 42.29717 ?  217 ARG   B N   1 
ATOM   3978 C CA  . ARG   B 1 217 ? 37.28907  -4.39596  9.86596   1.000 39.03990 ?  217 ARG   B CA  1 
ATOM   3979 C C   . ARG   B 1 217 ? 37.24248  -3.01546  10.49707  1.000 30.96738 ?  217 ARG   B C   1 
ATOM   3980 O O   . ARG   B 1 217 ? 36.60233  -2.86174  11.54316  1.000 33.78538 ?  217 ARG   B O   1 
ATOM   3981 C CB  . ARG   B 1 217 ? 37.83087  -5.37214  10.91738  1.000 38.89250 ?  217 ARG   B CB  1 
ATOM   3982 C CG  . ARG   B 1 217 ? 37.85874  -6.81543  10.49299  1.000 43.10542 ?  217 ARG   B CG  1 
ATOM   3983 C CD  . ARG   B 1 217 ? 38.49373  -7.65513  11.59692  1.000 39.72811 ?  217 ARG   B CD  1 
ATOM   3984 N NE  . ARG   B 1 217 ? 37.74626  -7.51039  12.83975  1.000 37.01513 ?  217 ARG   B NE  1 
ATOM   3985 C CZ  . ARG   B 1 217 ? 36.84386  -8.37536  13.27608  1.000 38.64140 ?  217 ARG   B CZ  1 
ATOM   3986 N NH1 . ARG   B 1 217 ? 36.59748  -9.50761  12.62861  1.000 43.41518 ?  217 ARG   B NH1 1 
ATOM   3987 N NH2 . ARG   B 1 217 ? 36.15936  -8.09300  14.37960  1.000 38.92225 ?  217 ARG   B NH2 1 
ATOM   3988 N N   . TRP   B 1 218 ? 37.86685  -2.01015  9.89008   1.000 32.66214 ?  218 TRP   B N   1 
ATOM   3989 C CA  . TRP   B 1 218 ? 38.02204  -0.71895  10.54952  1.000 31.64775 ?  218 TRP   B CA  1 
ATOM   3990 C C   . TRP   B 1 218 ? 36.68526  -0.07727  10.89663  1.000 35.40637 ?  218 TRP   B C   1 
ATOM   3991 O O   . TRP   B 1 218 ? 36.61734  0.73609   11.82247  1.000 33.31715 ?  218 TRP   B O   1 
ATOM   3992 C CB  . TRP   B 1 218 ? 38.84698  0.22538   9.67394   1.000 34.24127 ?  218 TRP   B CB  1 
ATOM   3993 C CG  . TRP   B 1 218 ? 38.20927  0.61458   8.34947   1.000 36.64911 ?  218 TRP   B CG  1 
ATOM   3994 C CD1 . TRP   B 1 218 ? 38.43320  0.03404   7.12408   1.000 36.36118 ?  218 TRP   B CD1 1 
ATOM   3995 C CD2 . TRP   B 1 218 ? 37.27805  1.67900   8.12343   1.000 40.09523 ?  218 TRP   B CD2 1 
ATOM   3996 N NE1 . TRP   B 1 218 ? 37.69204  0.67413   6.15511   1.000 36.12010 ?  218 TRP   B NE1 1 
ATOM   3997 C CE2 . TRP   B 1 218 ? 36.97173  1.68360   6.74111   1.000 38.18536 ?  218 TRP   B CE2 1 
ATOM   3998 C CE3 . TRP   B 1 218 ? 36.65893  2.62079   8.95437   1.000 37.11220 ?  218 TRP   B CE3 1 
ATOM   3999 C CZ2 . TRP   B 1 218 ? 36.07265  2.59026   6.17972   1.000 41.22866 ?  218 TRP   B CZ2 1 
ATOM   4000 C CZ3 . TRP   B 1 218 ? 35.77343  3.52002   8.39386   1.000 43.44229 ?  218 TRP   B CZ3 1 
ATOM   4001 C CH2 . TRP   B 1 218 ? 35.48731  3.49953   7.01572   1.000 41.99695 ?  218 TRP   B CH2 1 
ATOM   4002 N N   . PHE   B 1 219 ? 35.61937  -0.41710  10.16197  1.000 31.68888 ?  219 PHE   B N   1 
ATOM   4003 C CA  . PHE   B 1 219 ? 34.32258  0.23222   10.29043  1.000 31.05798 ?  219 PHE   B CA  1 
ATOM   4004 C C   . PHE   B 1 219 ? 33.46762  -0.36586  11.39752  1.000 31.12872 ?  219 PHE   B C   1 
ATOM   4005 O O   . PHE   B 1 219 ? 32.36991  0.14848   11.66040  1.000 30.74621 ?  219 PHE   B O   1 
ATOM   4006 C CB  . PHE   B 1 219 ? 33.55779  0.13505   8.94404   1.000 29.30635 ?  219 PHE   B CB  1 
ATOM   4007 C CG  . PHE   B 1 219 ? 33.54716  -1.25540  8.36409   1.000 30.99144 ?  219 PHE   B CG  1 
ATOM   4008 C CD1 . PHE   B 1 219 ? 32.60002  -2.19869  8.77716   1.000 29.08746 ?  219 PHE   B CD1 1 
ATOM   4009 C CD2 . PHE   B 1 219 ? 34.49767  -1.63732  7.42703   1.000 29.69889 ?  219 PHE   B CD2 1 
ATOM   4010 C CE1 . PHE   B 1 219 ? 32.60137  -3.50955  8.26824   1.000 28.21915 ?  219 PHE   B CE1 1 
ATOM   4011 C CE2 . PHE   B 1 219 ? 34.50445  -2.94515  6.91692   1.000 29.98990 ?  219 PHE   B CE2 1 
ATOM   4012 C CZ  . PHE   B 1 219 ? 33.56511  -3.87505  7.33649   1.000 28.11204 ?  219 PHE   B CZ  1 
ATOM   4013 N N   . LEU   B 1 220 ? 33.91226  -1.45366  12.01424  1.000 29.75407 ?  220 LEU   B N   1 
ATOM   4014 C CA  . LEU   B 1 220 ? 33.12387  -2.08261  13.06198  1.000 31.83393 ?  220 LEU   B CA  1 
ATOM   4015 C C   . LEU   B 1 220 ? 33.14385  -1.21641  14.31838  1.000 36.27729 ?  220 LEU   B C   1 
ATOM   4016 O O   . LEU   B 1 220 ? 34.06400  -0.41779  14.53511  1.000 33.37658 ?  220 LEU   B O   1 
ATOM   4017 C CB  . LEU   B 1 220 ? 33.65587  -3.47801  13.36861  1.000 33.05441 ?  220 LEU   B CB  1 
ATOM   4018 C CG  . LEU   B 1 220 ? 33.59558  -4.53881  12.25267  1.000 29.91772 ?  220 LEU   B CG  1 
ATOM   4019 C CD1 . LEU   B 1 220 ? 34.11070  -5.87399  12.73533  1.000 34.82172 ?  220 LEU   B CD1 1 
ATOM   4020 C CD2 . LEU   B 1 220 ? 32.17237  -4.71115  11.70768  1.000 29.85164 ?  220 LEU   B CD2 1 
ATOM   4021 N N   . ASN   B 1 221 ? 32.09110  -1.34471  15.12981  1.000 38.48527 ?  221 ASN   B N   1 
ATOM   4022 C CA  . ASN   B 1 221 ? 32.03622  -0.66878  16.42047  1.000 39.83772 ?  221 ASN   B CA  1 
ATOM   4023 C C   . ASN   B 1 221 ? 31.40283  -1.60722  17.44383  1.000 44.23096 ?  221 ASN   B C   1 
ATOM   4024 O O   . ASN   B 1 221 ? 30.91855  -2.69485  17.11603  1.000 38.00881 ?  221 ASN   B O   1 
ATOM   4025 C CB  . ASN   B 1 221 ? 31.31248  0.69412   16.33312  1.000 37.53421 ?  221 ASN   B CB  1 
ATOM   4026 C CG  . ASN   B 1 221 ? 29.86079  0.59252   15.86317  1.000 38.02542 ?  221 ASN   B CG  1 
ATOM   4027 O OD1 . ASN   B 1 221 ? 29.09595  -0.25333  16.31976  1.000 42.55094 ?  221 ASN   B OD1 1 
ATOM   4028 N ND2 . ASN   B 1 221 ? 29.48137  1.47418   14.95755  1.000 35.62438 ?  221 ASN   B ND2 1 
ATOM   4029 N N   . ARG   B 1 222 ? 31.44192  -1.20063  18.70847  1.000 45.65135 ?  222 ARG   B N   1 
ATOM   4030 C CA  . ARG   B 1 222 ? 30.88832  -2.04336  19.75702  1.000 47.23106 ?  222 ARG   B CA  1 
ATOM   4031 C C   . ARG   B 1 222 ? 29.43046  -1.72468  20.04450  1.000 50.32513 ?  222 ARG   B C   1 
ATOM   4032 O O   . ARG   B 1 222 ? 28.82642  -2.36472  20.91191  1.000 57.09409 ?  222 ARG   B O   1 
ATOM   4033 C CB  . ARG   B 1 222 ? 31.72156  -1.92798  21.03727  1.000 50.99659 ?  222 ARG   B CB  1 
ATOM   4034 C CG  . ARG   B 1 222 ? 31.61388  -0.60124  21.75463  1.000 54.44444 ?  222 ARG   B CG  1 
ATOM   4035 C CD  . ARG   B 1 222 ? 32.40585  -0.63956  23.06550  1.000 54.95280 ?  222 ARG   B CD  1 
ATOM   4036 N NE  . ARG   B 1 222 ? 32.21244  0.56822   23.85889  1.000 59.49468 ?  222 ARG   B NE  1 
ATOM   4037 C CZ  . ARG   B 1 222 ? 31.23337  0.74085   24.73948  1.000 62.58449 ?  222 ARG   B CZ  1 
ATOM   4038 N NH1 . ARG   B 1 222 ? 30.32748  -0.19830  24.96194  1.000 66.01403 ?  222 ARG   B NH1 1 
ATOM   4039 N NH2 . ARG   B 1 222 ? 31.16046  1.88535   25.41402  1.000 54.19734 ?  222 ARG   B NH2 1 
ATOM   4040 N N   . PHE   B 1 223 ? 28.84841  -0.78100  19.31615  1.000 49.24280 ?  223 PHE   B N   1 
ATOM   4041 C CA  . PHE   B 1 223 ? 27.46564  -0.39168  19.51858  1.000 49.54210 ?  223 PHE   B CA  1 
ATOM   4042 C C   . PHE   B 1 223 ? 26.50224  -1.40449  18.89098  1.000 46.01815 ?  223 PHE   B C   1 
ATOM   4043 O O   . PHE   B 1 223 ? 26.86688  -2.23807  18.04919  1.000 44.79969 ?  223 PHE   B O   1 
ATOM   4044 C CB  . PHE   B 1 223 ? 27.22285  1.00411   18.95008  1.000 44.14157 ?  223 PHE   B CB  1 
ATOM   4045 N N   . THR   B 1 224 ? 25.25478  -1.33459  19.33960  1.000 50.14489 ?  224 THR   B N   1 
ATOM   4046 C CA  . THR   B 1 224 ? 24.17184  -2.10933  18.75837  1.000 44.39379 ?  224 THR   B CA  1 
ATOM   4047 C C   . THR   B 1 224 ? 22.96261  -1.19473  18.61998  1.000 45.03277 ?  224 THR   B C   1 
ATOM   4048 O O   . THR   B 1 224 ? 22.90273  -0.11734  19.21386  1.000 47.16626 ?  224 THR   B O   1 
ATOM   4049 C CB  . THR   B 1 224 ? 23.83760  -3.34426  19.60196  1.000 49.34547 ?  224 THR   B CB  1 
ATOM   4050 O OG1 . THR   B 1 224 ? 23.11959  -4.29599  18.80015  1.000 48.46696 ?  224 THR   B OG1 1 
ATOM   4051 C CG2 . THR   B 1 224 ? 22.99074  -2.94360  20.79603  1.000 43.92648 ?  224 THR   B CG2 1 
ATOM   4052 N N   . THR   B 1 225 ? 22.01027  -1.61756  17.79409  1.000 39.83294 ?  225 THR   B N   1 
ATOM   4053 C CA  . THR   B 1 225 ? 20.82748  -0.82628  17.50117  1.000 35.53452 ?  225 THR   B CA  1 
ATOM   4054 C C   . THR   B 1 225 ? 19.63623  -1.76423  17.44577  1.000 33.81385 ?  225 THR   B C   1 
ATOM   4055 O O   . THR   B 1 225 ? 19.78693  -2.97277  17.26778  1.000 36.67411 ?  225 THR   B O   1 
ATOM   4056 C CB  . THR   B 1 225 ? 20.97577  -0.07808  16.16284  1.000 32.87269 ?  225 THR   B CB  1 
ATOM   4057 O OG1 . THR   B 1 225 ? 19.81114  0.71472   15.89788  1.000 35.30686 ?  225 THR   B OG1 1 
ATOM   4058 C CG2 . THR   B 1 225 ? 21.12889  -1.07967  15.03637  1.000 31.41803 ?  225 THR   B CG2 1 
ATOM   4059 N N   . THR   B 1 226 ? 18.44443  -1.20214  17.60255  1.000 31.45832 ?  226 THR   B N   1 
ATOM   4060 C CA  . THR   B 1 226 ? 17.25940  -1.96664  17.27337  1.000 32.65210 ?  226 THR   B CA  1 
ATOM   4061 C C   . THR   B 1 226 ? 17.00927  -1.88285  15.77219  1.000 28.77098 ?  226 THR   B C   1 
ATOM   4062 O O   . THR   B 1 226 ? 17.52101  -1.00157  15.07640  1.000 29.95130 ?  226 THR   B O   1 
ATOM   4063 C CB  . THR   B 1 226 ? 16.03059  -1.44880  18.01696  1.000 34.27826 ?  226 THR   B CB  1 
ATOM   4064 O OG1 . THR   B 1 226 ? 15.70121  -0.14843  17.51672  1.000 32.88833 ?  226 THR   B OG1 1 
ATOM   4065 C CG2 . THR   B 1 226 ? 16.29178  -1.36451  19.51351  1.000 36.21640 ?  226 THR   B CG2 1 
ATOM   4066 N N   . LEU   B 1 227 ? 16.20660  -2.81593  15.27045  1.000 27.26271 ?  227 LEU   B N   1 
ATOM   4067 C CA  . LEU   B 1 227 ? 15.87662  -2.79138  13.85348  1.000 27.87783 ?  227 LEU   B CA  1 
ATOM   4068 C C   . LEU   B 1 227 ? 15.12421  -1.51864  13.48183  1.000 28.53477 ?  227 LEU   B C   1 
ATOM   4069 O O   . LEU   B 1 227 ? 15.38452  -0.91165  12.43157  1.000 26.20601 ?  227 LEU   B O   1 
ATOM   4070 C CB  . LEU   B 1 227 ? 15.05192  -4.02186  13.50530  1.000 30.12002 ?  227 LEU   B CB  1 
ATOM   4071 C CG  . LEU   B 1 227 ? 14.60576  -4.13394  12.05212  1.000 27.01498 ?  227 LEU   B CG  1 
ATOM   4072 C CD1 . LEU   B 1 227 ? 15.78680  -4.16927  11.08419  1.000 25.81322 ?  227 LEU   B CD1 1 
ATOM   4073 C CD2 . LEU   B 1 227 ? 13.77710  -5.40589  11.90903  1.000 33.12366 ?  227 LEU   B CD2 1 
ATOM   4074 N N   . ASN   B 1 228 ? 14.19132  -1.09162  14.33591  1.000 27.92484 ?  228 ASN   B N   1 
ATOM   4075 C CA  . ASN   B 1 228 ? 13.42946  0.10983   14.00606  1.000 28.47288 ?  228 ASN   B CA  1 
ATOM   4076 C C   . ASN   B 1 228 ? 14.30053  1.35973   14.03348  1.000 28.59218 ?  228 ASN   B C   1 
ATOM   4077 O O   . ASN   B 1 228 ? 14.15467  2.23594   13.17476  1.000 28.00399 ?  228 ASN   B O   1 
ATOM   4078 C CB  . ASN   B 1 228 ? 12.25583  0.29268   14.95557  1.000 31.66868 ?  228 ASN   B CB  1 
ATOM   4079 C CG  . ASN   B 1 228 ? 11.42301  1.50181   14.59008  1.000 35.53362 ?  228 ASN   B CG  1 
ATOM   4080 O OD1 . ASN   B 1 228 ? 10.66972  1.46809   13.61892  1.000 35.05672 ?  228 ASN   B OD1 1 
ATOM   4081 N ND2 . ASN   B 1 228 ? 11.58137  2.58885   15.34552  1.000 36.42075 ?  228 ASN   B ND2 1 
ATOM   4082 N N   . ASP   B 1 229 ? 15.17294  1.49023   15.03178  1.000 28.13590 ?  229 ASP   B N   1 
ATOM   4083 C CA  . ASP   B 1 229 ? 16.03297  2.67613   15.06822  1.000 27.91350 ?  229 ASP   B CA  1 
ATOM   4084 C C   . ASP   B 1 229 ? 16.99634  2.68068   13.89398  1.000 29.28208 ?  229 ASP   B C   1 
ATOM   4085 O O   . ASP   B 1 229 ? 17.27650  3.74198   13.28674  1.000 28.57514 ?  229 ASP   B O   1 
ATOM   4086 C CB  . ASP   B 1 229 ? 16.78215  2.74067   16.39357  1.000 29.34326 ?  229 ASP   B CB  1 
ATOM   4087 C CG  . ASP   B 1 229 ? 15.83790  2.98702   17.58063  1.000 35.46620 ?  229 ASP   B CG  1 
ATOM   4088 O OD1 . ASP   B 1 229 ? 14.74948  3.56749   17.37387  1.000 36.11122 ?  229 ASP   B OD1 1 
ATOM   4089 O OD2 . ASP   B 1 229 ? 16.19539  2.56845   18.70268  1.000 41.30450 -1 229 ASP   B OD2 1 
ATOM   4090 N N   . PHE   B 1 230 ? 17.46153  1.48965   13.50969  1.000 25.41172 ?  230 PHE   B N   1 
ATOM   4091 C CA  . PHE   B 1 230 ? 18.26598  1.42436   12.30162  1.000 27.65175 ?  230 PHE   B CA  1 
ATOM   4092 C C   . PHE   B 1 230 ? 17.47179  1.92783   11.10870  1.000 25.94289 ?  230 PHE   B C   1 
ATOM   4093 O O   . PHE   B 1 230 ? 17.97487  2.72602   10.31768  1.000 26.50398 ?  230 PHE   B O   1 
ATOM   4094 C CB  . PHE   B 1 230 ? 18.77744  0.01318   12.02724  1.000 26.82024 ?  230 PHE   B CB  1 
ATOM   4095 C CG  . PHE   B 1 230 ? 19.43436  -0.08910  10.68027  1.000 25.83675 ?  230 PHE   B CG  1 
ATOM   4096 C CD1 . PHE   B 1 230 ? 20.66558  0.49117   10.47391  1.000 24.70523 ?  230 PHE   B CD1 1 
ATOM   4097 C CD2 . PHE   B 1 230 ? 18.76652  -0.66642  9.60311   1.000 26.29140 ?  230 PHE   B CD2 1 
ATOM   4098 C CE1 . PHE   B 1 230 ? 21.27860  0.46011   9.23642   1.000 26.22114 ?  230 PHE   B CE1 1 
ATOM   4099 C CE2 . PHE   B 1 230 ? 19.36482  -0.70266  8.36069   1.000 27.71430 ?  230 PHE   B CE2 1 
ATOM   4100 C CZ  . PHE   B 1 230 ? 20.63608  -0.13497  8.18082   1.000 26.93050 ?  230 PHE   B CZ  1 
ATOM   4101 N N   . ASN   B 1 231 ? 16.22478  1.46477   10.95684  1.000 25.45992 ?  231 ASN   B N   1 
ATOM   4102 C CA  . ASN   B 1 231 ? 15.42859  1.84385   9.79785   1.000 23.43695 ?  231 ASN   B CA  1 
ATOM   4103 C C   . ASN   B 1 231 ? 15.09466  3.33290   9.77647   1.000 25.15358 ?  231 ASN   B C   1 
ATOM   4104 O O   . ASN   B 1 231 ? 14.99368  3.92002   8.69369   1.000 28.45113 ?  231 ASN   B O   1 
ATOM   4105 C CB  . ASN   B 1 231 ? 14.15392  1.00622   9.75296   1.000 25.91853 ?  231 ASN   B CB  1 
ATOM   4106 C CG  . ASN   B 1 231 ? 14.40471  -0.33654  9.13074   1.000 30.83354 ?  231 ASN   B CG  1 
ATOM   4107 O OD1 . ASN   B 1 231 ? 15.27630  -0.44892  8.27566   1.000 30.52885 ?  231 ASN   B OD1 1 
ATOM   4108 N ND2 . ASN   B 1 231 ? 13.67229  -1.36549  9.56542   1.000 29.31772 ?  231 ASN   B ND2 1 
ATOM   4109 N N   . LEU   B 1 232 ? 14.93551  3.95815   10.94778  1.000 27.00221 ?  232 LEU   B N   1 
ATOM   4110 C CA  . LEU   B 1 232 ? 14.72097  5.40788   10.97410  1.000 28.24451 ?  232 LEU   B CA  1 
ATOM   4111 C C   . LEU   B 1 232 ? 15.89798  6.12236   10.32268  1.000 25.49322 ?  232 LEU   B C   1 
ATOM   4112 O O   . LEU   B 1 232 ? 15.71943  7.00124   9.45523   1.000 26.74915 ?  232 LEU   B O   1 
ATOM   4113 C CB  . LEU   B 1 232 ? 14.54447  5.89022   12.41941  1.000 27.62472 ?  232 LEU   B CB  1 
ATOM   4114 C CG  . LEU   B 1 232 ? 13.21923  5.50337   13.06993  1.000 27.20597 ?  232 LEU   B CG  1 
ATOM   4115 C CD1 . LEU   B 1 232 ? 13.20149  5.82529   14.55574  1.000 26.61939 ?  232 LEU   B CD1 1 
ATOM   4116 C CD2 . LEU   B 1 232 ? 12.07989  6.22175   12.35188  1.000 29.10326 ?  232 LEU   B CD2 1 
ATOM   4117 N N   . VAL   B 1 233 ? 17.11993  5.71544   10.69934  1.000 23.92119 ?  233 VAL   B N   1 
ATOM   4118 C CA  . VAL   B 1 233 ? 18.30605  6.37120   10.12625  1.000 27.92833 ?  233 VAL   B CA  1 
ATOM   4119 C C   . VAL   B 1 233 ? 18.47142  6.01652   8.64423   1.000 29.78338 ?  233 VAL   B C   1 
ATOM   4120 O O   . VAL   B 1 233 ? 18.75840  6.88358   7.79264   1.000 26.93431 ?  233 VAL   B O   1 
ATOM   4121 C CB  . VAL   B 1 233 ? 19.55217  6.00689   10.95670  1.000 30.31294 ?  233 VAL   B CB  1 
ATOM   4122 C CG1 . VAL   B 1 233 ? 20.83592  6.57129   10.31850  1.000 32.59107 ?  233 VAL   B CG1 1 
ATOM   4123 C CG2 . VAL   B 1 233 ? 19.39477  6.51049   12.36798  1.000 28.88771 ?  233 VAL   B CG2 1 
ATOM   4124 N N   . ALA   B 1 234 ? 18.29028  4.73811   8.30617   1.000 26.65515 ?  234 ALA   B N   1 
ATOM   4125 C CA  . ALA   B 1 234 ? 18.37569  4.33391   6.90548   1.000 30.55022 ?  234 ALA   B CA  1 
ATOM   4126 C C   . ALA   B 1 234 ? 17.45967  5.17508   6.02904   1.000 29.05657 ?  234 ALA   B C   1 
ATOM   4127 O O   . ALA   B 1 234 ? 17.89179  5.72789   5.01098   1.000 30.06086 ?  234 ALA   B O   1 
ATOM   4128 C CB  . ALA   B 1 234 ? 18.03798  2.84837   6.75832   1.000 29.46475 ?  234 ALA   B CB  1 
ATOM   4129 N N   . MET   B 1 235 ? 16.18920  5.29919   6.41849   1.000 26.17513 ?  235 MET   B N   1 
ATOM   4130 C CA  . MET   B 1 235 ? 15.24236  6.04463   5.60718   1.000 29.12479 ?  235 MET   B CA  1 
ATOM   4131 C C   . MET   B 1 235 ? 15.64046  7.50528   5.50568   1.000 27.69418 ?  235 MET   B C   1 
ATOM   4132 O O   . MET   B 1 235 ? 15.44814  8.11791   4.44691   1.000 29.77080 ?  235 MET   B O   1 
ATOM   4133 C CB  . MET   B 1 235 ? 13.84164  5.91016   6.18728   1.000 30.30377 ?  235 MET   B CB  1 
ATOM   4134 C CG  . MET   B 1 235 ? 13.26802  4.48743   6.06244   1.000 34.77041 ?  235 MET   B CG  1 
ATOM   4135 S SD  . MET   B 1 235 ? 11.57161  4.35493   6.65377   1.000 50.37411 ?  235 MET   B SD  1 
ATOM   4136 C CE  . MET   B 1 235 ? 10.81836  5.81798   5.93461   1.000 40.02436 ?  235 MET   B CE  1 
ATOM   4137 N N   . LYS   B 1 236 ? 16.19858  8.06373   6.58565   1.000 26.88105 ?  236 LYS   B N   1 
ATOM   4138 C CA  . LYS   B 1 236 ? 16.69927  9.43844   6.52995   1.000 28.53693 ?  236 LYS   B CA  1 
ATOM   4139 C C   . LYS   B 1 236 ? 17.73399  9.61024   5.42391   1.000 32.07765 ?  236 LYS   B C   1 
ATOM   4140 O O   . LYS   B 1 236 ? 17.76987  10.65512  4.75757   1.000 31.18226 ?  236 LYS   B O   1 
ATOM   4141 C CB  . LYS   B 1 236 ? 17.30542  9.81451   7.87747   1.000 29.05711 ?  236 LYS   B CB  1 
ATOM   4142 C CG  . LYS   B 1 236 ? 17.80470  11.26037  7.96232   1.000 27.63448 ?  236 LYS   B CG  1 
ATOM   4143 C CD  . LYS   B 1 236 ? 18.50806  11.53239  9.27281   1.000 29.43821 ?  236 LYS   B CD  1 
ATOM   4144 C CE  . LYS   B 1 236 ? 18.96532  12.98118  9.32781   1.000 36.17944 ?  236 LYS   B CE  1 
ATOM   4145 N NZ  . LYS   B 1 236 ? 19.79764  13.20828  10.54846  1.000 35.35889 ?  236 LYS   B NZ  1 
ATOM   4146 N N   . TYR   B 1 237 ? 18.58342  8.59944   5.21139   1.000 29.13759 ?  237 TYR   B N   1 
ATOM   4147 C CA  . TYR   B 1 237 ? 19.62521  8.67096   4.19011   1.000 26.95996 ?  237 TYR   B CA  1 
ATOM   4148 C C   . TYR   B 1 237 ? 19.22299  8.06414   2.84462   1.000 28.13159 ?  237 TYR   B C   1 
ATOM   4149 O O   . TYR   B 1 237 ? 20.10126  7.79190   2.01575   1.000 29.77685 ?  237 TYR   B O   1 
ATOM   4150 C CB  . TYR   B 1 237 ? 20.89638  7.99712   4.69875   1.000 28.37512 ?  237 TYR   B CB  1 
ATOM   4151 C CG  . TYR   B 1 237 ? 21.56963  8.84059   5.73672   1.000 27.72007 ?  237 TYR   B CG  1 
ATOM   4152 C CD1 . TYR   B 1 237 ? 22.48407  9.82539   5.37558   1.000 36.70496 ?  237 TYR   B CD1 1 
ATOM   4153 C CD2 . TYR   B 1 237 ? 21.26692  8.68007   7.07776   1.000 31.13345 ?  237 TYR   B CD2 1 
ATOM   4154 C CE1 . TYR   B 1 237 ? 23.08805  10.62300  6.34434   1.000 34.11538 ?  237 TYR   B CE1 1 
ATOM   4155 C CE2 . TYR   B 1 237 ? 21.86236  9.46583   8.04856   1.000 37.94794 ?  237 TYR   B CE2 1 
ATOM   4156 C CZ  . TYR   B 1 237 ? 22.76990  10.43001  7.67831   1.000 41.99333 ?  237 TYR   B CZ  1 
ATOM   4157 O OH  . TYR   B 1 237 ? 23.36048  11.20181  8.65967   1.000 40.52237 ?  237 TYR   B OH  1 
ATOM   4158 N N   . ASN   B 1 238 ? 17.93202  7.86357   2.60220   1.000 28.35383 ?  238 ASN   B N   1 
ATOM   4159 C CA  . ASN   B 1 238 ? 17.45277  7.30005   1.33796   1.000 30.16023 ?  238 ASN   B CA  1 
ATOM   4160 C C   . ASN   B 1 238 ? 17.99512  5.89256   1.11053   1.000 29.66624 ?  238 ASN   B C   1 
ATOM   4161 O O   . ASN   B 1 238 ? 18.30708  5.49589   -0.01827  1.000 31.19946 ?  238 ASN   B O   1 
ATOM   4162 C CB  . ASN   B 1 238 ? 17.78222  8.20453   0.15430   1.000 34.98156 ?  238 ASN   B CB  1 
ATOM   4163 C CG  . ASN   B 1 238 ? 16.57935  9.00024   -0.29830  1.000 36.97854 ?  238 ASN   B CG  1 
ATOM   4164 O OD1 . ASN   B 1 238 ? 15.45428  8.52394   -0.20514  1.000 39.88362 ?  238 ASN   B OD1 1 
ATOM   4165 N ND2 . ASN   B 1 238 ? 16.80712  10.22036  -0.75738  1.000 44.80972 ?  238 ASN   B ND2 1 
ATOM   4166 N N   . TYR   B 1 239 ? 18.09884  5.13812   2.19574   1.000 28.52745 ?  239 TYR   B N   1 
ATOM   4167 C CA  . TYR   B 1 239 ? 18.31647  3.70038   2.14695   1.000 26.79445 ?  239 TYR   B CA  1 
ATOM   4168 C C   . TYR   B 1 239 ? 16.98705  2.97762   2.29955   1.000 28.27972 ?  239 TYR   B C   1 
ATOM   4169 O O   . TYR   B 1 239 ? 16.11280  3.41730   3.05856   1.000 27.53284 ?  239 TYR   B O   1 
ATOM   4170 C CB  . TYR   B 1 239 ? 19.26879  3.26770   3.26891   1.000 25.35912 ?  239 TYR   B CB  1 
ATOM   4171 C CG  . TYR   B 1 239 ? 20.73607  3.33067   2.91474   1.000 25.78420 ?  239 TYR   B CG  1 
ATOM   4172 C CD1 . TYR   B 1 239 ? 21.30256  4.48400   2.41692   1.000 27.29319 ?  239 TYR   B CD1 1 
ATOM   4173 C CD2 . TYR   B 1 239 ? 21.55689  2.21570   3.08794   1.000 28.85876 ?  239 TYR   B CD2 1 
ATOM   4174 C CE1 . TYR   B 1 239 ? 22.66010  4.54335   2.10097   1.000 28.53711 ?  239 TYR   B CE1 1 
ATOM   4175 C CE2 . TYR   B 1 239 ? 22.91501  2.26256   2.77282   1.000 29.77339 ?  239 TYR   B CE2 1 
ATOM   4176 C CZ  . TYR   B 1 239 ? 23.44981  3.42360   2.27485   1.000 33.31275 ?  239 TYR   B CZ  1 
ATOM   4177 O OH  . TYR   B 1 239 ? 24.79095  3.47508   1.95150   1.000 37.47222 ?  239 TYR   B OH  1 
ATOM   4178 N N   . GLU   B 1 240 ? 16.83537  1.86025   1.58875   1.000 26.95774 ?  240 GLU   B N   1 
ATOM   4179 C CA  . GLU   B 1 240 ? 15.64350  1.04147   1.74534   1.000 27.60093 ?  240 GLU   B CA  1 
ATOM   4180 C C   . GLU   B 1 240 ? 15.53614  0.48068   3.16428   1.000 28.26355 ?  240 GLU   B C   1 
ATOM   4181 O O   . GLU   B 1 240 ? 16.54676  0.17473   3.81144   1.000 27.33056 ?  240 GLU   B O   1 
ATOM   4182 C CB  . GLU   B 1 240 ? 15.64462  -0.11939  0.74611   1.000 30.02704 ?  240 GLU   B CB  1 
ATOM   4183 C CG  . GLU   B 1 240 ? 15.51392  0.32469   -0.70037  1.000 33.45085 ?  240 GLU   B CG  1 
ATOM   4184 C CD  . GLU   B 1 240 ? 14.09662  0.76476   -1.05227  1.000 38.88063 ?  240 GLU   B CD  1 
ATOM   4185 O OE1 . GLU   B 1 240 ? 13.15311  -0.02667  -0.83423  1.000 45.60092 ?  240 GLU   B OE1 1 
ATOM   4186 O OE2 . GLU   B 1 240 ? 13.92225  1.89981   -1.54854  1.000 38.40490 -1 240 GLU   B OE2 1 
ATOM   4187 N N   . PRO   B 1 241 ? 14.31608  0.30345   3.66070   1.000 30.83684 ?  241 PRO   B N   1 
ATOM   4188 C CA  . PRO   B 1 241 ? 14.14657  -0.31101  4.98020   1.000 31.87305 ?  241 PRO   B CA  1 
ATOM   4189 C C   . PRO   B 1 241 ? 14.67430  -1.73581  4.96579   1.000 28.88666 ?  241 PRO   B C   1 
ATOM   4190 O O   . PRO   B 1 241 ? 14.66767  -2.40864  3.93272   1.000 30.53989 ?  241 PRO   B O   1 
ATOM   4191 C CB  . PRO   B 1 241 ? 12.62606  -0.29198  5.19582   1.000 36.06327 ?  241 PRO   B CB  1 
ATOM   4192 C CG  . PRO   B 1 241 ? 12.05602  0.55016   4.09450   1.000 36.85079 ?  241 PRO   B CG  1 
ATOM   4193 C CD  . PRO   B 1 241 ? 13.02990  0.52486   2.97223   1.000 35.49071 ?  241 PRO   B CD  1 
ATOM   4194 N N   . LEU   B 1 242 ? 15.15098  -2.17889  6.11635   1.000 29.48042 ?  242 LEU   B N   1 
ATOM   4195 C CA  . LEU   B 1 242 ? 15.58283  -3.55645  6.30778   1.000 27.44956 ?  242 LEU   B CA  1 
ATOM   4196 C C   . LEU   B 1 242 ? 14.44144  -4.32490  6.96527   1.000 30.04363 ?  242 LEU   B C   1 
ATOM   4197 O O   . LEU   B 1 242 ? 13.97478  -3.93832  8.04191   1.000 30.80944 ?  242 LEU   B O   1 
ATOM   4198 C CB  . LEU   B 1 242 ? 16.83944  -3.59405  7.17980   1.000 25.08026 ?  242 LEU   B CB  1 
ATOM   4199 C CG  . LEU   B 1 242 ? 17.62029  -4.88979  7.17605   1.000 26.91956 ?  242 LEU   B CG  1 
ATOM   4200 C CD1 . LEU   B 1 242 ? 18.35938  -5.08642  5.84472   1.000 28.75468 ?  242 LEU   B CD1 1 
ATOM   4201 C CD2 . LEU   B 1 242 ? 18.59694  -4.86178  8.32137   1.000 29.31676 ?  242 LEU   B CD2 1 
ATOM   4202 N N   . THR   B 1 243 ? 13.99089  -5.40970  6.32660   1.000 28.26741 ?  243 THR   B N   1 
ATOM   4203 C CA  . THR   B 1 243 ? 12.92542  -6.21978  6.89644   1.000 30.76298 ?  243 THR   B CA  1 
ATOM   4204 C C   . THR   B 1 243 ? 13.48289  -7.39301  7.70861   1.000 32.45014 ?  243 THR   B C   1 
ATOM   4205 O O   . THR   B 1 243 ? 14.66451  -7.73530  7.64426   1.000 29.92739 ?  243 THR   B O   1 
ATOM   4206 C CB  . THR   B 1 243 ? 12.01964  -6.76133  5.78692   1.000 30.88712 ?  243 THR   B CB  1 
ATOM   4207 O OG1 . THR   B 1 243 ? 12.76123  -7.73342  5.05045   1.000 32.47934 ?  243 THR   B OG1 1 
ATOM   4208 C CG2 . THR   B 1 243 ? 11.62130  -5.64794  4.83700   1.000 34.74966 ?  243 THR   B CG2 1 
ATOM   4209 N N   . GLN   B 1 244 ? 12.59826  -8.03719  8.47554   1.000 34.07490 ?  244 GLN   B N   1 
ATOM   4210 C CA  . GLN   B 1 244 ? 13.02066  -9.21701  9.22232   1.000 36.57283 ?  244 GLN   B CA  1 
ATOM   4211 C C   . GLN   B 1 244 ? 13.41087  -10.35863 8.28346   1.000 32.67306 ?  244 GLN   B C   1 
ATOM   4212 O O   . GLN   B 1 244 ? 14.30771  -11.13965 8.61252   1.000 34.71368 ?  244 GLN   B O   1 
ATOM   4213 C CB  . GLN   B 1 244 ? 11.91568  -9.66799  10.18517  1.000 38.39160 ?  244 GLN   B CB  1 
ATOM   4214 C CG  . GLN   B 1 244 ? 12.30430  -10.80275 11.13026  1.000 40.43115 ?  244 GLN   B CG  1 
ATOM   4215 C CD  . GLN   B 1 244 ? 13.50741  -10.47119 11.99661  1.000 40.78544 ?  244 GLN   B CD  1 
ATOM   4216 O OE1 . GLN   B 1 244 ? 13.58034  -9.39885  12.60113  1.000 41.58406 ?  244 GLN   B OE1 1 
ATOM   4217 N NE2 . GLN   B 1 244 ? 14.47259  -11.39029 12.04605  1.000 40.80093 ?  244 GLN   B NE2 1 
ATOM   4218 N N   . ASP   B 1 245 ? 12.75720  -10.47133 7.12572   1.000 35.24658 ?  245 ASP   B N   1 
ATOM   4219 C CA  . ASP   B 1 245 ? 13.23329  -11.41100 6.11266   1.000 34.48078 ?  245 ASP   B CA  1 
ATOM   4220 C C   . ASP   B 1 245 ? 14.67709  -11.10312 5.72073   1.000 34.80077 ?  245 ASP   B C   1 
ATOM   4221 O O   . ASP   B 1 245 ? 15.49718  -12.01700 5.57938   1.000 33.37278 ?  245 ASP   B O   1 
ATOM   4222 C CB  . ASP   B 1 245 ? 12.32869  -11.38190 4.87747   1.000 38.67218 ?  245 ASP   B CB  1 
ATOM   4223 C CG  . ASP   B 1 245 ? 10.92490  -11.92498 5.15027   1.000 47.44489 ?  245 ASP   B CG  1 
ATOM   4224 O OD1 . ASP   B 1 245 ? 10.66663  -12.42084 6.26933   1.000 50.89605 ?  245 ASP   B OD1 1 
ATOM   4225 O OD2 . ASP   B 1 245 ? 10.07130  -11.85505 4.23223   1.000 52.00338 -1 245 ASP   B OD2 1 
ATOM   4226 N N   . HIS   B 1 246 ? 15.01371  -9.81879  5.54899   1.000 30.22584 ?  246 HIS   B N   1 
ATOM   4227 C CA  . HIS   B 1 246 ? 16.39700  -9.46480  5.24418   1.000 30.58543 ?  246 HIS   B CA  1 
ATOM   4228 C C   . HIS   B 1 246 ? 17.32230  -9.88077  6.37349   1.000 32.15907 ?  246 HIS   B C   1 
ATOM   4229 O O   . HIS   B 1 246 ? 18.42149  -10.39100 6.12950   1.000 31.10506 ?  246 HIS   B O   1 
ATOM   4230 C CB  . HIS   B 1 246 ? 16.55637  -7.95686  5.01089   1.000 29.38637 ?  246 HIS   B CB  1 
ATOM   4231 C CG  . HIS   B 1 246 ? 15.86298  -7.42390  3.79930   1.000 30.78713 ?  246 HIS   B CG  1 
ATOM   4232 N ND1 . HIS   B 1 246 ? 15.39615  -6.12851  3.73323   1.000 28.94128 ?  246 HIS   B ND1 1 
ATOM   4233 C CD2 . HIS   B 1 246 ? 15.58867  -7.98358  2.59417   1.000 32.08006 ?  246 HIS   B CD2 1 
ATOM   4234 C CE1 . HIS   B 1 246 ? 14.83702  -5.92155  2.55372   1.000 31.68388 ?  246 HIS   B CE1 1 
ATOM   4235 N NE2 . HIS   B 1 246 ? 14.94670  -7.03062  1.83995   1.000 33.25192 ?  246 HIS   B NE2 1 
ATOM   4236 N N   . VAL   B 1 247 ? 16.91202  -9.63814  7.62318   1.000 28.07315 ?  247 VAL   B N   1 
ATOM   4237 C CA  . VAL   B 1 247 ? 17.73821  -10.05296 8.75156   1.000 29.65448 ?  247 VAL   B CA  1 
ATOM   4238 C C   . VAL   B 1 247 ? 17.98672  -11.55091 8.69085   1.000 31.39975 ?  247 VAL   B C   1 
ATOM   4239 O O   . VAL   B 1 247 ? 19.11174  -12.01781 8.90609   1.000 31.22577 ?  247 VAL   B O   1 
ATOM   4240 C CB  . VAL   B 1 247 ? 17.08057  -9.64435  10.08403  1.000 29.58127 ?  247 VAL   B CB  1 
ATOM   4241 C CG1 . VAL   B 1 247 ? 17.88127  -10.17255 11.25771  1.000 32.09746 ?  247 VAL   B CG1 1 
ATOM   4242 C CG2 . VAL   B 1 247 ? 16.97460  -8.11920  10.17789  1.000 30.54520 ?  247 VAL   B CG2 1 
ATOM   4243 N N   . ASP   B 1 248 ? 16.94287  -12.32424 8.37665   1.000 34.25194 ?  248 ASP   B N   1 
ATOM   4244 C CA  . ASP   B 1 248 ? 17.08382  -13.77861 8.35975   1.000 35.78213 ?  248 ASP   B CA  1 
ATOM   4245 C C   . ASP   B 1 248 ? 18.02688  -14.22372 7.25036   1.000 33.79972 ?  248 ASP   B C   1 
ATOM   4246 O O   . ASP   B 1 248 ? 18.85224  -15.12564 7.44866   1.000 36.29214 ?  248 ASP   B O   1 
ATOM   4247 C CB  . ASP   B 1 248 ? 15.71369  -14.44115 8.19364   1.000 35.48440 ?  248 ASP   B CB  1 
ATOM   4248 C CG  . ASP   B 1 248 ? 14.79574  -14.21094 9.38351   1.000 37.51940 ?  248 ASP   B CG  1 
ATOM   4249 O OD1 . ASP   B 1 248 ? 15.28618  -13.98270 10.51462  1.000 41.86274 ?  248 ASP   B OD1 1 
ATOM   4250 O OD2 . ASP   B 1 248 ? 13.57210  -14.28339 9.18852   1.000 42.14535 -1 248 ASP   B OD2 1 
ATOM   4251 N N   . ILE   B 1 249 ? 17.92337  -13.59402 6.07867   1.000 31.83742 ?  249 ILE   B N   1 
ATOM   4252 C CA  . ILE   B 1 249 ? 18.75386  -13.95666 4.92979   1.000 34.22201 ?  249 ILE   B CA  1 
ATOM   4253 C C   . ILE   B 1 249 ? 20.21835  -13.66215 5.19051   1.000 36.69356 ?  249 ILE   B C   1 
ATOM   4254 O O   . ILE   B 1 249 ? 21.10613  -14.31390 4.62338   1.000 36.10446 ?  249 ILE   B O   1 
ATOM   4255 C CB  . ILE   B 1 249 ? 18.23934  -13.21849 3.68048   1.000 35.34202 ?  249 ILE   B CB  1 
ATOM   4256 C CG1 . ILE   B 1 249 ? 16.89396  -13.78981 3.24730   1.000 36.40092 ?  249 ILE   B CG1 1 
ATOM   4257 C CG2 . ILE   B 1 249 ? 19.22553  -13.28304 2.52624   1.000 38.35389 ?  249 ILE   B CG2 1 
ATOM   4258 C CD1 . ILE   B 1 249 ? 16.02287  -12.76789 2.55861   1.000 39.98666 ?  249 ILE   B CD1 1 
ATOM   4259 N N   . LEU   B 1 250 ? 20.50638  -12.68950 6.04803   1.000 31.33513 ?  250 LEU   B N   1 
ATOM   4260 C CA  . LEU   B 1 250 ? 21.87733  -12.39298 6.41408   1.000 27.95328 ?  250 LEU   B CA  1 
ATOM   4261 C C   . LEU   B 1 250 ? 22.40592  -13.32856 7.49443   1.000 29.90981 ?  250 LEU   B C   1 
ATOM   4262 O O   . LEU   B 1 250 ? 23.58586  -13.23590 7.83679   1.000 32.71371 ?  250 LEU   B O   1 
ATOM   4263 C CB  . LEU   B 1 250 ? 21.99083  -10.93790 6.89272   1.000 28.47969 ?  250 LEU   B CB  1 
ATOM   4264 C CG  . LEU   B 1 250 ? 21.88100  -9.83929  5.83914   1.000 25.82724 ?  250 LEU   B CG  1 
ATOM   4265 C CD1 . LEU   B 1 250 ? 21.65657  -8.51473  6.56162   1.000 24.81109 ?  250 LEU   B CD1 1 
ATOM   4266 C CD2 . LEU   B 1 250 ? 23.16970  -9.76657  5.02558   1.000 26.39418 ?  250 LEU   B CD2 1 
ATOM   4267 N N   . GLY   B 1 251 ? 21.55850  -14.21961 8.01873   1.000 32.14241 ?  251 GLY   B N   1 
ATOM   4268 C CA  . GLY   B 1 251 ? 21.91099  -15.14111 9.07581   1.000 36.70889 ?  251 GLY   B CA  1 
ATOM   4269 C C   . GLY   B 1 251 ? 23.20053  -15.92073 8.85668   1.000 36.90794 ?  251 GLY   B C   1 
ATOM   4270 O O   . GLY   B 1 251 ? 24.05384  -15.98439 9.74398   1.000 36.07842 ?  251 GLY   B O   1 
ATOM   4271 N N   . PRO   B 1 252 ? 23.35616  -16.55622 7.68580   1.000 35.91451 ?  252 PRO   B N   1 
ATOM   4272 C CA  . PRO   B 1 252 ? 24.59367  -17.32261 7.44114   1.000 35.32289 ?  252 PRO   B CA  1 
ATOM   4273 C C   . PRO   B 1 252 ? 25.85691  -16.48657 7.49474   1.000 37.75698 ?  252 PRO   B C   1 
ATOM   4274 O O   . PRO   B 1 252 ? 26.88477  -16.95273 8.00864   1.000 37.70935 ?  252 PRO   B O   1 
ATOM   4275 C CB  . PRO   B 1 252 ? 24.35882  -17.90481 6.04162   1.000 30.34179 ?  252 PRO   B CB  1 
ATOM   4276 C CG  . PRO   B 1 252 ? 22.91868  -18.04877 5.95220   1.000 40.12931 ?  252 PRO   B CG  1 
ATOM   4277 C CD  . PRO   B 1 252 ? 22.34553  -16.84254 6.65721   1.000 37.17677 ?  252 PRO   B CD  1 
ATOM   4278 N N   . LEU   B 1 253 ? 25.81593  -15.25075 6.98694   1.000 32.65767 ?  253 LEU   B N   1 
ATOM   4279 C CA  . LEU   B 1 253 ? 26.98497  -14.38285 7.07811   1.000 33.95279 ?  253 LEU   B CA  1 
ATOM   4280 C C   . LEU   B 1 253 ? 27.22988  -13.94962 8.52032   1.000 33.56326 ?  253 LEU   B C   1 
ATOM   4281 O O   . LEU   B 1 253 ? 28.38316  -13.79794 8.95679   1.000 33.71946 ?  253 LEU   B O   1 
ATOM   4282 C CB  . LEU   B 1 253 ? 26.80051  -13.16554 6.16488   1.000 30.92781 ?  253 LEU   B CB  1 
ATOM   4283 C CG  . LEU   B 1 253 ? 26.64358  -13.48129 4.67398   1.000 34.18931 ?  253 LEU   B CG  1 
ATOM   4284 C CD1 . LEU   B 1 253 ? 26.24036  -12.22596 3.90044   1.000 30.97624 ?  253 LEU   B CD1 1 
ATOM   4285 C CD2 . LEU   B 1 253 ? 27.93116  -14.05053 4.10617   1.000 35.20193 ?  253 LEU   B CD2 1 
ATOM   4286 N N   . SER   B 1 254 ? 26.14955  -13.76166 9.28122   1.000 34.67188 ?  254 SER   B N   1 
ATOM   4287 C CA  . SER   B 1 254 ? 26.29996  -13.41636 10.68805  1.000 33.70735 ?  254 SER   B CA  1 
ATOM   4288 C C   . SER   B 1 254 ? 26.97099  -14.55699 11.44956  1.000 34.20701 ?  254 SER   B C   1 
ATOM   4289 O O   . SER   B 1 254 ? 27.89744  -14.33610 12.23567  1.000 35.76470 ?  254 SER   B O   1 
ATOM   4290 C CB  . SER   B 1 254 ? 24.93034  -13.09189 11.28868  1.000 35.44050 ?  254 SER   B CB  1 
ATOM   4291 O OG  . SER   B 1 254 ? 25.07135  -12.63959 12.62229  1.000 39.92337 ?  254 SER   B OG  1 
ATOM   4292 N N   . ALA   B 1 255 ? 26.52431  -15.78475 11.20320  1.000 37.83836 ?  255 ALA   B N   1 
ATOM   4293 C CA  . ALA   B 1 255 ? 27.13247  -16.94838 11.83746  1.000 40.15756 ?  255 ALA   B CA  1 
ATOM   4294 C C   . ALA   B 1 255 ? 28.58304  -17.12447 11.40378  1.000 37.87123 ?  255 ALA   B C   1 
ATOM   4295 O O   . ALA   B 1 255 ? 29.44403  -17.45322 12.22461  1.000 44.85625 ?  255 ALA   B O   1 
ATOM   4296 C CB  . ALA   B 1 255 ? 26.32146  -18.19938 11.51097  1.000 36.07560 ?  255 ALA   B CB  1 
ATOM   4297 N N   . GLN   B 1 256 ? 28.87703  -16.92072 10.12114  1.000 39.66680 ?  256 GLN   B N   1 
ATOM   4298 C CA  . GLN   B 1 256 ? 30.24076  -17.13418 9.65551   1.000 38.79571 ?  256 GLN   B CA  1 
ATOM   4299 C C   . GLN   B 1 256 ? 31.20972  -16.14183 10.28842  1.000 42.59592 ?  256 GLN   B C   1 
ATOM   4300 O O   . GLN   B 1 256 ? 32.36041  -16.50268 10.57362  1.000 42.28295 ?  256 GLN   B O   1 
ATOM   4301 C CB  . GLN   B 1 256 ? 30.30004  -17.06491 8.12344   1.000 40.45842 ?  256 GLN   B CB  1 
ATOM   4302 C CG  . GLN   B 1 256 ? 31.71243  -17.24638 7.57105   1.000 45.91396 ?  256 GLN   B CG  1 
ATOM   4303 C CD  . GLN   B 1 256 ? 31.76562  -17.29924 6.05572   1.000 47.29309 ?  256 GLN   B CD  1 
ATOM   4304 O OE1 . GLN   B 1 256 ? 30.73661  -17.22970 5.37561   1.000 51.56911 ?  256 GLN   B OE1 1 
ATOM   4305 N NE2 . GLN   B 1 256 ? 32.97658  -17.42888 5.51510   1.000 47.75869 ?  256 GLN   B NE2 1 
ATOM   4306 N N   . THR   B 1 257 ? 30.76107  -14.90447 10.55419  1.000 37.19210 ?  257 THR   B N   1 
ATOM   4307 C CA  . THR   B 1 257 ? 31.62353  -13.87100 11.11799  1.000 35.53632 ?  257 THR   B CA  1 
ATOM   4308 C C   . THR   B 1 257 ? 31.47386  -13.68389 12.62515  1.000 34.46469 ?  257 THR   B C   1 
ATOM   4309 O O   . THR   B 1 257 ? 32.31967  -13.01674 13.23407  1.000 36.94053 ?  257 THR   B O   1 
ATOM   4310 C CB  . THR   B 1 257 ? 31.33610  -12.51089 10.45910  1.000 37.05675 ?  257 THR   B CB  1 
ATOM   4311 O OG1 . THR   B 1 257 ? 29.94862  -12.21425 10.62446  1.000 36.66835 ?  257 THR   B OG1 1 
ATOM   4312 C CG2 . THR   B 1 257 ? 31.67305  -12.51789 8.96935   1.000 33.94695 ?  257 THR   B CG2 1 
ATOM   4313 N N   . GLY   B 1 258 ? 30.42220  -14.21998 13.23829  1.000 35.29035 ?  258 GLY   B N   1 
ATOM   4314 C CA  . GLY   B 1 258 ? 30.19919  -13.94411 14.64535  1.000 37.12036 ?  258 GLY   B CA  1 
ATOM   4315 C C   . GLY   B 1 258 ? 29.73475  -12.53786 14.94722  1.000 41.35087 ?  258 GLY   B C   1 
ATOM   4316 O O   . GLY   B 1 258 ? 29.84522  -12.07590 16.08799  1.000 37.20441 ?  258 GLY   B O   1 
ATOM   4317 N N   . ILE   B 1 259 ? 29.22566  -11.82709 13.94662  1.000 35.04675 ?  259 ILE   B N   1 
ATOM   4318 C CA  . ILE   B 1 259 ? 28.77037  -10.45440 14.10585  1.000 34.02845 ?  259 ILE   B CA  1 
ATOM   4319 C C   . ILE   B 1 259 ? 27.26760  -10.43222 13.88212  1.000 35.43000 ?  259 ILE   B C   1 
ATOM   4320 O O   . ILE   B 1 259 ? 26.79627  -10.72616 12.77778  1.000 31.97414 ?  259 ILE   B O   1 
ATOM   4321 C CB  . ILE   B 1 259 ? 29.48657  -9.50685  13.13517  1.000 33.92192 ?  259 ILE   B CB  1 
ATOM   4322 C CG1 . ILE   B 1 259 ? 30.99521  -9.54987  13.38025  1.000 35.54795 ?  259 ILE   B CG1 1 
ATOM   4323 C CG2 . ILE   B 1 259 ? 28.93158  -8.09325  13.26810  1.000 30.30745 ?  259 ILE   B CG2 1 
ATOM   4324 C CD1 . ILE   B 1 259 ? 31.80167  -8.82543  12.34143  1.000 35.45450 ?  259 ILE   B CD1 1 
ATOM   4325 N N   . ALA   B 1 260 ? 26.51634  -10.08847 14.92772  1.000 33.19760 ?  260 ALA   B N   1 
ATOM   4326 C CA  . ALA   B 1 260 ? 25.06840  -10.06428 14.82725  1.000 33.37343 ?  260 ALA   B CA  1 
ATOM   4327 C C   . ALA   B 1 260 ? 24.65407  -9.06409  13.76157  1.000 27.39119 ?  260 ALA   B C   1 
ATOM   4328 O O   . ALA   B 1 260 ? 25.30737  -8.03211  13.56917  1.000 28.45150 ?  260 ALA   B O   1 
ATOM   4329 C CB  . ALA   B 1 260 ? 24.42672  -9.67422  16.16143  1.000 35.45954 ?  260 ALA   B CB  1 
ATOM   4330 N N   . VAL   B 1 261 ? 23.55791  -9.37827  13.07553  1.000 28.99835 ?  261 VAL   B N   1 
ATOM   4331 C CA  . VAL   B 1 261 ? 23.07869  -8.49032  12.01945  1.000 27.68633 ?  261 VAL   B CA  1 
ATOM   4332 C C   . VAL   B 1 261 ? 22.85893  -7.08323  12.56334  1.000 27.97034 ?  261 VAL   B C   1 
ATOM   4333 O O   . VAL   B 1 261 ? 23.27287  -6.09592  11.94989  1.000 26.16089 ?  261 VAL   B O   1 
ATOM   4334 C CB  . VAL   B 1 261 ? 21.79666  -9.03745  11.37352  1.000 28.43576 ?  261 VAL   B CB  1 
ATOM   4335 C CG1 . VAL   B 1 261 ? 21.26278  -8.03055  10.35573  1.000 27.49410 ?  261 VAL   B CG1 1 
ATOM   4336 C CG2 . VAL   B 1 261 ? 22.06506  -10.38324 10.69675  1.000 30.55590 ?  261 VAL   B CG2 1 
ATOM   4337 N N   . LEU   B 1 262 ? 22.20391  -6.96247  13.72311  1.000 29.53651 ?  262 LEU   B N   1 
ATOM   4338 C CA  . LEU   B 1 262 ? 21.98755  -5.61338  14.25599  1.000 31.12871 ?  262 LEU   B CA  1 
ATOM   4339 C C   . LEU   B 1 262 ? 23.28429  -4.91813  14.69991  1.000 31.52053 ?  262 LEU   B C   1 
ATOM   4340 O O   . LEU   B 1 262 ? 23.34199  -3.68221  14.70185  1.000 32.42882 ?  262 LEU   B O   1 
ATOM   4341 C CB  . LEU   B 1 262 ? 20.96887  -5.65992  15.39725  1.000 29.68287 ?  262 LEU   B CB  1 
ATOM   4342 C CG  . LEU   B 1 262 ? 19.53057  -5.98503  14.96745  1.000 31.92028 ?  262 LEU   B CG  1 
ATOM   4343 C CD1 . LEU   B 1 262 ? 18.62785  -6.10752  16.20408  1.000 37.24268 ?  262 LEU   B CD1 1 
ATOM   4344 C CD2 . LEU   B 1 262 ? 18.94361  -4.96833  13.97052  1.000 34.47683 ?  262 LEU   B CD2 1 
ATOM   4345 N N   . ASP   B 1 263 ? 24.34787  -5.66272  15.02231  1.000 30.05252 ?  263 ASP   B N   1 
ATOM   4346 C CA  . ASP   B 1 263 ? 25.63749  -5.01691  15.25997  1.000 31.20605 ?  263 ASP   B CA  1 
ATOM   4347 C C   . ASP   B 1 263 ? 26.21483  -4.45433  13.96610  1.000 28.03811 ?  263 ASP   B C   1 
ATOM   4348 O O   . ASP   B 1 263 ? 26.79841  -3.35428  13.94017  1.000 29.47730 ?  263 ASP   B O   1 
ATOM   4349 C CB  . ASP   B 1 263 ? 26.61129  -6.01419  15.89592  1.000 31.73922 ?  263 ASP   B CB  1 
ATOM   4350 C CG  . ASP   B 1 263 ? 26.35439  -6.19913  17.36587  1.000 44.45470 ?  263 ASP   B CG  1 
ATOM   4351 O OD1 . ASP   B 1 263 ? 27.01752  -7.06845  17.98680  1.000 46.93180 ?  263 ASP   B OD1 1 
ATOM   4352 O OD2 . ASP   B 1 263 ? 25.47622  -5.46511  17.88626  1.000 44.15921 -1 263 ASP   B OD2 1 
ATOM   4353 N N   . MET   B 1 264 ? 26.05088  -5.19495  12.86795  1.000 28.68258 ?  264 MET   B N   1 
ATOM   4354 C CA  . MET   B 1 264 ? 26.48754  -4.65385  11.59218  1.000 27.49101 ?  264 MET   B CA  1 
ATOM   4355 C C   . MET   B 1 264 ? 25.65051  -3.44508  11.20995  1.000 24.25338 ?  264 MET   B C   1 
ATOM   4356 O O   . MET   B 1 264 ? 26.16125  -2.51141  10.59069  1.000 25.51911 ?  264 MET   B O   1 
ATOM   4357 C CB  . MET   B 1 264 ? 26.42008  -5.73549  10.50162  1.000 26.75252 ?  264 MET   B CB  1 
ATOM   4358 C CG  . MET   B 1 264 ? 27.18712  -5.37358  9.23576   1.000 30.73659 ?  264 MET   B CG  1 
ATOM   4359 S SD  . MET   B 1 264 ? 28.97969  -5.15043  9.52351   1.000 28.13073 ?  264 MET   B SD  1 
ATOM   4360 C CE  . MET   B 1 264 ? 29.49358  -6.87562  9.39413   1.000 28.07667 ?  264 MET   B CE  1 
ATOM   4361 N N   . CYS   B 1 265 ? 24.36681  -3.45015  11.56124  1.000 25.12596 ?  265 CYS   B N   1 
ATOM   4362 C CA  . CYS   B 1 265 ? 23.52449  -2.28092  11.31536  1.000 24.03067 ?  265 CYS   B CA  1 
ATOM   4363 C C   . CYS   B 1 265 ? 24.04547  -1.06321  12.06025  1.000 26.78241 ?  265 CYS   B C   1 
ATOM   4364 O O   . CYS   B 1 265 ? 24.03347  0.05876   11.53334  1.000 24.25731 ?  265 CYS   B O   1 
ATOM   4365 C CB  . CYS   B 1 265 ? 22.08601  -2.58033  11.72133  1.000 25.90025 ?  265 CYS   B CB  1 
ATOM   4366 S SG  . CYS   B 1 265 ? 21.24375  -3.75134  10.62586  1.000 27.50661 ?  265 CYS   B SG  1 
ATOM   4367 N N   . ALA   B 1 266 ? 24.48796  -1.25735  13.30144  1.000 25.97116 ?  266 ALA   B N   1 
ATOM   4368 C CA  . ALA   B 1 266 ? 25.07010  -0.12601  14.02699  1.000 27.37615 ?  266 ALA   B CA  1 
ATOM   4369 C C   . ALA   B 1 266 ? 26.31084  0.40074   13.31513  1.000 28.52168 ?  266 ALA   B C   1 
ATOM   4370 O O   . ALA   B 1 266 ? 26.55578  1.61983   13.26815  1.000 28.82136 ?  266 ALA   B O   1 
ATOM   4371 C CB  . ALA   B 1 266 ? 25.41259  -0.54934  15.45253  1.000 31.70962 ?  266 ALA   B CB  1 
ATOM   4372 N N   . SER   B 1 267 ? 27.10877  -0.50942  12.74740  1.000 28.41747 ?  267 SER   B N   1 
ATOM   4373 C CA  . SER   B 1 267 ? 28.26982  -0.06084  11.97703  1.000 28.78012 ?  267 SER   B CA  1 
ATOM   4374 C C   . SER   B 1 267 ? 27.84504  0.75405   10.76574  1.000 29.14296 ?  267 SER   B C   1 
ATOM   4375 O O   . SER   B 1 267 ? 28.41963  1.81487   10.47683  1.000 29.32081 ?  267 SER   B O   1 
ATOM   4376 C CB  . SER   B 1 267 ? 29.12007  -1.25475  11.54893  1.000 30.54076 ?  267 SER   B CB  1 
ATOM   4377 O OG  . SER   B 1 267 ? 29.72737  -1.83126  12.68373  1.000 39.83525 ?  267 SER   B OG  1 
ATOM   4378 N N   . LEU   B 1 268 ? 26.83806  0.26147   10.03493  1.000 25.79250 ?  268 LEU   B N   1 
ATOM   4379 C CA  . LEU   B 1 268 ? 26.35330  0.98354   8.86434   1.000 25.01377 ?  268 LEU   B CA  1 
ATOM   4380 C C   . LEU   B 1 268 ? 25.81337  2.36413   9.24449   1.000 27.63812 ?  268 LEU   B C   1 
ATOM   4381 O O   . LEU   B 1 268 ? 26.08499  3.35234   8.55722   1.000 28.31845 ?  268 LEU   B O   1 
ATOM   4382 C CB  . LEU   B 1 268 ? 25.29602  0.13629   8.14677   1.000 23.21753 ?  268 LEU   B CB  1 
ATOM   4383 C CG  . LEU   B 1 268 ? 24.69263  0.76251   6.87518   1.000 23.87906 ?  268 LEU   B CG  1 
ATOM   4384 C CD1 . LEU   B 1 268 ? 25.75688  1.30575   5.90770   1.000 26.05741 ?  268 LEU   B CD1 1 
ATOM   4385 C CD2 . LEU   B 1 268 ? 23.83856  -0.28675  6.17234   1.000 26.27521 ?  268 LEU   B CD2 1 
ATOM   4386 N N   . LYS   B 1 269 ? 25.05649  2.45205   10.34127  1.000 26.28455 ?  269 LYS   B N   1 
ATOM   4387 C CA  . LYS   B 1 269 ? 24.52600  3.73649   10.78962  1.000 29.42245 ?  269 LYS   B CA  1 
ATOM   4388 C C   . LYS   B 1 269 ? 25.65879  4.72707   11.05985  1.000 27.92785 ?  269 LYS   B C   1 
ATOM   4389 O O   . LYS   B 1 269 ? 25.58207  5.89769   10.65751  1.000 34.06758 ?  269 LYS   B O   1 
ATOM   4390 C CB  . LYS   B 1 269 ? 23.67022  3.52798   12.04675  1.000 31.85335 ?  269 LYS   B CB  1 
ATOM   4391 C CG  . LYS   B 1 269 ? 22.92473  4.77491   12.54464  1.000 36.71151 ?  269 LYS   B CG  1 
ATOM   4392 C CD  . LYS   B 1 269 ? 22.41906  4.58771   13.99077  1.000 36.24607 ?  269 LYS   B CD  1 
ATOM   4393 C CE  . LYS   B 1 269 ? 21.29948  3.54851   14.11182  1.000 37.47799 ?  269 LYS   B CE  1 
ATOM   4394 N NZ  . LYS   B 1 269 ? 20.82891  3.39206   15.53093  1.000 34.55149 ?  269 LYS   B NZ  1 
ATOM   4395 N N   . GLU   B 1 270 ? 26.72735  4.26539   11.72184  1.000 30.25220 ?  270 GLU   B N   1 
ATOM   4396 C CA  . GLU   B 1 270 ? 27.87960  5.14098   11.94082  1.000 32.32857 ?  270 GLU   B CA  1 
ATOM   4397 C C   . GLU   B 1 270 ? 28.48309  5.59235   10.61002  1.000 36.80206 ?  270 GLU   B C   1 
ATOM   4398 O O   . GLU   B 1 270 ? 28.78487  6.77695   10.42791  1.000 38.15289 ?  270 GLU   B O   1 
ATOM   4399 C CB  . GLU   B 1 270 ? 28.93057  4.44034   12.82218  1.000 32.65717 ?  270 GLU   B CB  1 
ATOM   4400 C CG  . GLU   B 1 270 ? 30.21341  5.25680   13.02852  1.000 42.95200 ?  270 GLU   B CG  1 
ATOM   4401 C CD  . GLU   B 1 270 ? 31.14584  4.70048   14.12031  1.000 50.56394 ?  270 GLU   B CD  1 
ATOM   4402 O OE1 . GLU   B 1 270 ? 31.47243  3.48541   14.11659  1.000 42.44387 ?  270 GLU   B OE1 1 
ATOM   4403 O OE2 . GLU   B 1 270 ? 31.56859  5.49933   14.98568  1.000 52.48628 -1 270 GLU   B OE2 1 
ATOM   4404 N N   . LEU   B 1 271 ? 28.63252  4.66649   9.65091   1.000 37.02735 ?  271 LEU   B N   1 
ATOM   4405 C CA  . LEU   B 1 271 ? 29.16206  5.05455   8.34065   1.000 37.22398 ?  271 LEU   B CA  1 
ATOM   4406 C C   . LEU   B 1 271 ? 28.26548  6.07632   7.65118   1.000 38.74383 ?  271 LEU   B C   1 
ATOM   4407 O O   . LEU   B 1 271 ? 28.75519  6.98514   6.96828   1.000 39.02092 ?  271 LEU   B O   1 
ATOM   4408 C CB  . LEU   B 1 271 ? 29.34450  3.82427   7.45307   1.000 31.58822 ?  271 LEU   B CB  1 
ATOM   4409 C CG  . LEU   B 1 271 ? 30.51498  2.91982   7.83706   1.000 32.50032 ?  271 LEU   B CG  1 
ATOM   4410 C CD1 . LEU   B 1 271 ? 30.37003  1.54748   7.18238   1.000 29.36435 ?  271 LEU   B CD1 1 
ATOM   4411 C CD2 . LEU   B 1 271 ? 31.84651  3.57654   7.45048   1.000 36.98875 ?  271 LEU   B CD2 1 
ATOM   4412 N N   . LEU   B 1 272 ? 26.94769  5.94345   7.80459   1.000 32.51943 ?  272 LEU   B N   1 
ATOM   4413 C CA  . LEU   B 1 272 ? 26.04803  6.86137   7.11608   1.000 34.55594 ?  272 LEU   B CA  1 
ATOM   4414 C C   . LEU   B 1 272 ? 26.15192  8.26372   7.68801   1.000 41.68657 ?  272 LEU   B C   1 
ATOM   4415 O O   . LEU   B 1 272 ? 26.12738  9.24968   6.94053   1.000 38.97465 ?  272 LEU   B O   1 
ATOM   4416 C CB  . LEU   B 1 272 ? 24.60832  6.37228   7.20066   1.000 32.54179 ?  272 LEU   B CB  1 
ATOM   4417 C CG  . LEU   B 1 272 ? 24.37074  5.11634   6.37178   1.000 29.87675 ?  272 LEU   B CG  1 
ATOM   4418 C CD1 . LEU   B 1 272 ? 22.91667  4.71734   6.43086   1.000 29.34050 ?  272 LEU   B CD1 1 
ATOM   4419 C CD2 . LEU   B 1 272 ? 24.82829  5.36871   4.94758   1.000 34.59995 ?  272 LEU   B CD2 1 
ATOM   4420 N N   . GLN   B 1 273 ? 26.24163  8.38791   9.00545   1.000 37.32126 ?  273 GLN   B N   1 
ATOM   4421 C CA  . GLN   B 1 273 ? 26.25018  9.74416   9.53526   1.000 43.96141 ?  273 GLN   B CA  1 
ATOM   4422 C C   . GLN   B 1 273 ? 27.65024  10.30073  9.78242   1.000 44.77508 ?  273 GLN   B C   1 
ATOM   4423 O O   . GLN   B 1 273 ? 27.76421  11.46544  10.16970  1.000 52.14263 ?  273 GLN   B O   1 
ATOM   4424 C CB  . GLN   B 1 273 ? 25.39460  9.84039   10.80175  1.000 45.18059 ?  273 GLN   B CB  1 
ATOM   4425 C CG  . GLN   B 1 273 ? 25.51458  8.70641   11.75737  1.000 45.90739 ?  273 GLN   B CG  1 
ATOM   4426 C CD  . GLN   B 1 273 ? 24.29477  8.58043   12.64930  1.000 43.16665 ?  273 GLN   B CD  1 
ATOM   4427 O OE1 . GLN   B 1 273 ? 23.17785  8.92145   12.25435  1.000 52.82961 ?  273 GLN   B OE1 1 
ATOM   4428 N NE2 . GLN   B 1 273 ? 24.50080  8.08244   13.85139  1.000 43.16157 ?  273 GLN   B NE2 1 
ATOM   4429 N N   . ASN   B 1 274 ? 28.71371  9.52800   9.52237   1.000 44.11394 ?  274 ASN   B N   1 
ATOM   4430 C CA  . ASN   B 1 274 ? 30.08947  10.00555  9.64351   1.000 43.32971 ?  274 ASN   B CA  1 
ATOM   4431 C C   . ASN   B 1 274 ? 30.88691  9.97265   8.35154   1.000 47.89070 ?  274 ASN   B C   1 
ATOM   4432 O O   . ASN   B 1 274 ? 31.90194  10.67480  8.25970   1.000 47.39208 ?  274 ASN   B O   1 
ATOM   4433 C CB  . ASN   B 1 274 ? 30.87197  9.17684   10.67072  1.000 46.13353 ?  274 ASN   B CB  1 
ATOM   4434 C CG  . ASN   B 1 274 ? 30.36745  9.36448   12.07545  1.000 50.07429 ?  274 ASN   B CG  1 
ATOM   4435 O OD1 . ASN   B 1 274 ? 29.46601  10.17247  12.32621  1.000 52.88644 ?  274 ASN   B OD1 1 
ATOM   4436 N ND2 . ASN   B 1 274 ? 30.93684  8.60961   13.00803  1.000 47.84610 ?  274 ASN   B ND2 1 
ATOM   4437 N N   . GLY   B 1 275 ? 30.49363  9.16490   7.37259   1.000 43.70132 ?  275 GLY   B N   1 
ATOM   4438 C CA  . GLY   B 1 275 ? 31.31213  8.98285   6.19575   1.000 42.46398 ?  275 GLY   B CA  1 
ATOM   4439 C C   . GLY   B 1 275 ? 32.45049  8.02012   6.45092   1.000 46.50356 ?  275 GLY   B C   1 
ATOM   4440 O O   . GLY   B 1 275 ? 32.59836  7.43810   7.52824   1.000 49.21136 ?  275 GLY   B O   1 
ATOM   4441 N N   . MET   B 1 276 ? 33.27989  7.84868   5.42368   1.000 47.42190 ?  276 MET   B N   1 
ATOM   4442 C CA  . MET   B 1 276 ? 34.40206  6.92493   5.49048   1.000 49.62187 ?  276 MET   B CA  1 
ATOM   4443 C C   . MET   B 1 276 ? 35.72185  7.61346   5.81768   1.000 51.03890 ?  276 MET   B C   1 
ATOM   4444 O O   . MET   B 1 276 ? 36.71765  6.92467   6.05016   1.000 50.71131 ?  276 MET   B O   1 
ATOM   4445 C CB  . MET   B 1 276 ? 34.50197  6.13759   4.17660   1.000 47.15991 ?  276 MET   B CB  1 
ATOM   4446 C CG  . MET   B 1 276 ? 33.45628  5.01322   4.11344   1.000 46.28510 ?  276 MET   B CG  1 
ATOM   4447 S SD  . MET   B 1 276 ? 32.83811  4.51182   2.48658   1.000 53.95905 ?  276 MET   B SD  1 
ATOM   4448 C CE  . MET   B 1 276 ? 34.19195  3.46927   1.97003   1.000 40.06623 ?  276 MET   B CE  1 
ATOM   4449 N N   . ASN   B 1 277 ? 35.73746  8.94605   5.89400   1.000 52.15723 ?  277 ASN   B N   1 
ATOM   4450 C CA  . ASN   B 1 277 ? 36.94644  9.71525   6.20287   1.000 56.79738 ?  277 ASN   B CA  1 
ATOM   4451 C C   . ASN   B 1 277 ? 38.08809  9.34742   5.25606   1.000 53.86481 ?  277 ASN   B C   1 
ATOM   4452 O O   . ASN   B 1 277 ? 39.20985  9.06706   5.68080   1.000 53.04497 ?  277 ASN   B O   1 
ATOM   4453 C CB  . ASN   B 1 277 ? 37.37582  9.51981   7.66021   1.000 53.42988 ?  277 ASN   B CB  1 
ATOM   4454 C CG  . ASN   B 1 277 ? 36.19865  9.40828   8.61142   1.000 58.59278 ?  277 ASN   B CG  1 
ATOM   4455 O OD1 . ASN   B 1 277 ? 35.32036  10.27483  8.64935   1.000 59.01686 ?  277 ASN   B OD1 1 
ATOM   4456 N ND2 . ASN   B 1 277 ? 36.17108  8.32316   9.38292   1.000 61.41034 ?  277 ASN   B ND2 1 
ATOM   4457 N N   . GLY   B 1 278 ? 37.78573  9.32596   3.95980   1.000 52.48196 ?  278 GLY   B N   1 
ATOM   4458 C CA  . GLY   B 1 278 ? 38.79116  9.02994   2.95586   1.000 52.20042 ?  278 GLY   B CA  1 
ATOM   4459 C C   . GLY   B 1 278 ? 39.33305  7.61655   3.00902   1.000 54.41246 ?  278 GLY   B C   1 
ATOM   4460 O O   . GLY   B 1 278 ? 40.30181  7.28936   2.31372   1.000 51.77024 ?  278 GLY   B O   1 
ATOM   4461 N N   . ARG   B 1 279 ? 38.72674  6.77032   3.83703   1.000 48.75339 ?  279 ARG   B N   1 
ATOM   4462 C CA  . ARG   B 1 279 ? 39.11661  5.37400   3.87534   1.000 45.23777 ?  279 ARG   B CA  1 
ATOM   4463 C C   . ARG   B 1 279 ? 38.34088  4.58615   2.82542   1.000 40.74187 ?  279 ARG   B C   1 
ATOM   4464 O O   . ARG   B 1 279 ? 37.42524  5.09729   2.17623   1.000 44.58733 ?  279 ARG   B O   1 
ATOM   4465 C CB  . ARG   B 1 279 ? 38.88340  4.78525   5.26074   1.000 45.85621 ?  279 ARG   B CB  1 
ATOM   4466 C CG  . ARG   B 1 279 ? 39.56473  5.55864   6.37477   1.000 48.83492 ?  279 ARG   B CG  1 
ATOM   4467 C CD  . ARG   B 1 279 ? 39.67640  4.71094   7.62221   1.000 48.61279 ?  279 ARG   B CD  1 
ATOM   4468 N NE  . ARG   B 1 279 ? 40.55517  3.56321   7.41336   1.000 48.90524 ?  279 ARG   B NE  1 
ATOM   4469 C CZ  . ARG   B 1 279 ? 41.10124  2.84411   8.38573   1.000 51.17287 ?  279 ARG   B CZ  1 
ATOM   4470 N NH1 . ARG   B 1 279 ? 40.88640  3.12922   9.66029   1.000 53.44109 ?  279 ARG   B NH1 1 
ATOM   4471 N NH2 . ARG   B 1 279 ? 41.88430  1.81352   8.07215   1.000 50.90952 ?  279 ARG   B NH2 1 
ATOM   4472 N N   . THR   B 1 280 ? 38.72612  3.32230   2.65501   1.000 39.21442 ?  280 THR   B N   1 
ATOM   4473 C CA  . THR   B 1 280 ? 38.10015  2.45861   1.66741   1.000 36.80262 ?  280 THR   B CA  1 
ATOM   4474 C C   . THR   B 1 280 ? 37.68805  1.14196   2.30846   1.000 34.53309 ?  280 THR   B C   1 
ATOM   4475 O O   . THR   B 1 280 ? 38.24584  0.70821   3.32054   1.000 36.39561 ?  280 THR   B O   1 
ATOM   4476 C CB  . THR   B 1 280 ? 39.03545  2.18252   0.47149   1.000 37.97614 ?  280 THR   B CB  1 
ATOM   4477 O OG1 . THR   B 1 280 ? 40.19703  1.47552   0.91854   1.000 38.44535 ?  280 THR   B OG1 1 
ATOM   4478 C CG2 . THR   B 1 280 ? 39.47638  3.48176   -0.17048  1.000 40.96231 ?  280 THR   B CG2 1 
ATOM   4479 N N   . ILE   B 1 281 ? 36.70469  0.49410   1.68893   1.000 30.32342 ?  281 ILE   B N   1 
ATOM   4480 C CA  . ILE   B 1 281 ? 36.25032  -0.82572  2.09324   1.000 30.98419 ?  281 ILE   B CA  1 
ATOM   4481 C C   . ILE   B 1 281 ? 36.28042  -1.69730  0.85612   1.000 31.92520 ?  281 ILE   B C   1 
ATOM   4482 O O   . ILE   B 1 281 ? 35.64699  -1.36069  -0.15082  1.000 29.97638 ?  281 ILE   B O   1 
ATOM   4483 C CB  . ILE   B 1 281 ? 34.83865  -0.79934  2.69581   1.000 29.64412 ?  281 ILE   B CB  1 
ATOM   4484 C CG1 . ILE   B 1 281 ? 34.81365  0.10038   3.93112   1.000 33.00833 ?  281 ILE   B CG1 1 
ATOM   4485 C CG2 . ILE   B 1 281 ? 34.38096  -2.21047  3.01102   1.000 29.87005 ?  281 ILE   B CG2 1 
ATOM   4486 C CD1 . ILE   B 1 281 ? 33.42539  0.34867   4.47198   1.000 34.58363 ?  281 ILE   B CD1 1 
ATOM   4487 N N   . LEU   B 1 282 ? 37.02680  -2.79508  0.91884   1.000 34.06720 ?  282 LEU   B N   1 
ATOM   4488 C CA  . LEU   B 1 282 ? 37.21435  -3.66256  -0.24407  1.000 35.79323 ?  282 LEU   B CA  1 
ATOM   4489 C C   . LEU   B 1 282 ? 37.59313  -2.85020  -1.48167  1.000 34.41347 ?  282 LEU   B C   1 
ATOM   4490 O O   . LEU   B 1 282 ? 37.10461  -3.09959  -2.58797  1.000 40.62782 ?  282 LEU   B O   1 
ATOM   4491 C CB  . LEU   B 1 282 ? 35.96751  -4.50157  -0.50365  1.000 33.05146 ?  282 LEU   B CB  1 
ATOM   4492 C CG  . LEU   B 1 282 ? 35.74550  -5.69120  0.42877   1.000 33.16361 ?  282 LEU   B CG  1 
ATOM   4493 C CD1 . LEU   B 1 282 ? 34.43072  -6.37322  0.15241   1.000 30.75319 ?  282 LEU   B CD1 1 
ATOM   4494 C CD2 . LEU   B 1 282 ? 36.88903  -6.69695  0.33412   1.000 34.43290 ?  282 LEU   B CD2 1 
ATOM   4495 N N   . GLY   B 1 283 ? 38.45334  -1.85183  -1.28373  1.000 34.76904 ?  283 GLY   B N   1 
ATOM   4496 C CA  . GLY   B 1 283 ? 38.95413  -1.00997  -2.35118  1.000 35.61903 ?  283 GLY   B CA  1 
ATOM   4497 C C   . GLY   B 1 283 ? 37.98803  0.03524   -2.86833  1.000 37.22640 ?  283 GLY   B C   1 
ATOM   4498 O O   . GLY   B 1 283 ? 38.32411  0.73983   -3.82864  1.000 38.57585 ?  283 GLY   B O   1 
ATOM   4499 N N   . SER   B 1 284 ? 36.81287  0.17006   -2.26396  1.000 32.49904 ?  284 SER   B N   1 
ATOM   4500 C CA  . SER   B 1 284 ? 35.80772  1.12638   -2.69861  1.000 33.12853 ?  284 SER   B CA  1 
ATOM   4501 C C   . SER   B 1 284 ? 35.77158  2.33979   -1.76946  1.000 34.27612 ?  284 SER   B C   1 
ATOM   4502 O O   . SER   B 1 284 ? 35.88076  2.20712   -0.54610  1.000 34.05040 ?  284 SER   B O   1 
ATOM   4503 C CB  . SER   B 1 284 ? 34.43413  0.44405   -2.75615  1.000 35.00737 ?  284 SER   B CB  1 
ATOM   4504 O OG  . SER   B 1 284 ? 33.40012  1.35481   -3.08670  1.000 36.37566 ?  284 SER   B OG  1 
ATOM   4505 N N   . ALA   B 1 285 ? 35.62586  3.52703   -2.35844  1.000 39.52350 ?  285 ALA   B N   1 
ATOM   4506 C CA  . ALA   B 1 285 ? 35.38779  4.74755   -1.59997  1.000 35.48327 ?  285 ALA   B CA  1 
ATOM   4507 C C   . ALA   B 1 285 ? 33.90574  5.01526   -1.35755  1.000 39.96751 ?  285 ALA   B C   1 
ATOM   4508 O O   . ALA   B 1 285 ? 33.56981  6.00441   -0.69524  1.000 41.24342 ?  285 ALA   B O   1 
ATOM   4509 C CB  . ALA   B 1 285 ? 36.01162  5.94980   -2.31499  1.000 42.15093 ?  285 ALA   B CB  1 
ATOM   4510 N N   . LEU   B 1 286 ? 33.01869  4.16949   -1.87909  1.000 33.70044 ?  286 LEU   B N   1 
ATOM   4511 C CA  . LEU   B 1 286 ? 31.58521  4.28577   -1.65524  1.000 36.68047 ?  286 LEU   B CA  1 
ATOM   4512 C C   . LEU   B 1 286 ? 31.03404  2.95566   -1.15412  1.000 35.50315 ?  286 LEU   B C   1 
ATOM   4513 O O   . LEU   B 1 286 ? 31.63665  1.89774   -1.35721  1.000 35.52574 ?  286 LEU   B O   1 
ATOM   4514 C CB  . LEU   B 1 286 ? 30.85123  4.69570   -2.93893  1.000 39.81451 ?  286 LEU   B CB  1 
ATOM   4515 C CG  . LEU   B 1 286 ? 31.34581  5.95626   -3.64911  1.000 41.80375 ?  286 LEU   B CG  1 
ATOM   4516 C CD1 . LEU   B 1 286 ? 30.60840  6.11341   -4.96969  1.000 42.49733 ?  286 LEU   B CD1 1 
ATOM   4517 C CD2 . LEU   B 1 286 ? 31.17044  7.19095   -2.79058  1.000 46.12244 ?  286 LEU   B CD2 1 
ATOM   4518 N N   . LEU   B 1 287 ? 29.86544  3.00857   -0.51125  1.000 32.44359 ?  287 LEU   B N   1 
ATOM   4519 C CA  . LEU   B 1 287 ? 29.24080  1.79456   -0.00439  1.000 28.72255 ?  287 LEU   B CA  1 
ATOM   4520 C C   . LEU   B 1 287 ? 28.53484  1.07665   -1.15355  1.000 31.27893 ?  287 LEU   B C   1 
ATOM   4521 O O   . LEU   B 1 287 ? 27.63058  1.63238   -1.78912  1.000 35.25045 ?  287 LEU   B O   1 
ATOM   4522 C CB  . LEU   B 1 287 ? 28.26942  2.11784   1.12726   1.000 28.71317 ?  287 LEU   B CB  1 
ATOM   4523 C CG  . LEU   B 1 287 ? 28.90687  2.87354   2.30239   1.000 30.45906 ?  287 LEU   B CG  1 
ATOM   4524 C CD1 . LEU   B 1 287 ? 27.83274  3.32478   3.28318   1.000 35.54621 ?  287 LEU   B CD1 1 
ATOM   4525 C CD2 . LEU   B 1 287 ? 29.96603  2.01301   2.99757   1.000 38.25209 ?  287 LEU   B CD2 1 
ATOM   4526 N N   . GLU   B 1 288 ? 28.95756  -0.14758  -1.41502  1.000 27.26844 ?  288 GLU   B N   1 
ATOM   4527 C CA  . GLU   B 1 288 ? 28.52793  -0.92372  -2.56725  1.000 27.19513 ?  288 GLU   B CA  1 
ATOM   4528 C C   . GLU   B 1 288 ? 27.22447  -1.64438  -2.24487  1.000 28.22635 ?  288 GLU   B C   1 
ATOM   4529 O O   . GLU   B 1 288 ? 27.11362  -2.28258  -1.19265  1.000 27.22251 ?  288 GLU   B O   1 
ATOM   4530 C CB  . GLU   B 1 288 ? 29.62797  -1.92107  -2.93549  1.000 28.08199 ?  288 GLU   B CB  1 
ATOM   4531 C CG  . GLU   B 1 288 ? 29.20726  -3.01265  -3.89585  1.000 34.63553 ?  288 GLU   B CG  1 
ATOM   4532 C CD  . GLU   B 1 288 ? 29.07838  -2.47865  -5.30815  1.000 41.12016 ?  288 GLU   B CD  1 
ATOM   4533 O OE1 . GLU   B 1 288 ? 29.97010  -1.70199  -5.71045  1.000 45.02334 ?  288 GLU   B OE1 1 
ATOM   4534 O OE2 . GLU   B 1 288 ? 28.08188  -2.79919  -5.99023  1.000 34.18785 -1 288 GLU   B OE2 1 
ATOM   4535 N N   . ASP   B 1 289 ? 26.22952  -1.56275  -3.15618  1.000 25.34691 ?  289 ASP   B N   1 
ATOM   4536 C CA  . ASP   B 1 289 ? 24.92967  -2.16170  -2.86565  1.000 25.63421 ?  289 ASP   B CA  1 
ATOM   4537 C C   . ASP   B 1 289 ? 24.45225  -3.11949  -3.95321  1.000 25.98834 ?  289 ASP   B C   1 
ATOM   4538 O O   . ASP   B 1 289 ? 23.27817  -3.49074  -3.96552  1.000 25.23877 ?  289 ASP   B O   1 
ATOM   4539 C CB  . ASP   B 1 289 ? 23.87823  -1.07646  -2.58275  1.000 26.77843 ?  289 ASP   B CB  1 
ATOM   4540 C CG  . ASP   B 1 289 ? 23.43099  -0.31210  -3.83129  1.000 28.25352 ?  289 ASP   B CG  1 
ATOM   4541 O OD1 . ASP   B 1 289 ? 24.16991  -0.27475  -4.85272  1.000 27.33728 ?  289 ASP   B OD1 1 
ATOM   4542 O OD2 . ASP   B 1 289 ? 22.32749  0.27091   -3.75158  1.000 27.96254 -1 289 ASP   B OD2 1 
ATOM   4543 N N   . GLU   B 1 290 ? 25.34918  -3.61073  -4.80849  1.000 24.53552 ?  290 GLU   B N   1 
ATOM   4544 C CA  . GLU   B 1 290 ? 24.93944  -4.54716  -5.85017  1.000 27.31762 ?  290 GLU   B CA  1 
ATOM   4545 C C   . GLU   B 1 290 ? 25.51093  -5.95792  -5.66132  1.000 33.11385 ?  290 GLU   B C   1 
ATOM   4546 O O   . GLU   B 1 290 ? 25.72057  -6.68692  -6.63852  1.000 28.77863 ?  290 GLU   B O   1 
ATOM   4547 C CB  . GLU   B 1 290 ? 25.28350  -3.95537  -7.21811  1.000 30.62540 ?  290 GLU   B CB  1 
ATOM   4548 C CG  . GLU   B 1 290 ? 24.55803  -2.60015  -7.42941  1.000 31.07487 ?  290 GLU   B CG  1 
ATOM   4549 C CD  . GLU   B 1 290 ? 24.35975  -2.20681  -8.89967  1.000 36.19880 ?  290 GLU   B CD  1 
ATOM   4550 O OE1 . GLU   B 1 290 ? 24.90240  -2.90078  -9.78326  1.000 32.66790 ?  290 GLU   B OE1 1 
ATOM   4551 O OE2 . GLU   B 1 290 ? 23.67142  -1.18645  -9.16146  1.000 33.15202 -1 290 GLU   B OE2 1 
ATOM   4552 N N   . PHE   B 1 291 ? 25.74292  -6.37126  -4.40615  1.000 26.46091 ?  291 PHE   B N   1 
ATOM   4553 C CA  . PHE   B 1 291 ? 25.94545  -7.77309  -4.04369  1.000 30.34344 ?  291 PHE   B CA  1 
ATOM   4554 C C   . PHE   B 1 291 ? 24.81666  -8.21591  -3.12760  1.000 28.75123 ?  291 PHE   B C   1 
ATOM   4555 O O   . PHE   B 1 291 ? 24.63804  -7.63712  -2.05398  1.000 28.69897 ?  291 PHE   B O   1 
ATOM   4556 C CB  . PHE   B 1 291 ? 27.25490  -7.99325  -3.29643  1.000 30.81094 ?  291 PHE   B CB  1 
ATOM   4557 C CG  . PHE   B 1 291 ? 28.48268  -7.80629  -4.11619  1.000 32.84815 ?  291 PHE   B CG  1 
ATOM   4558 C CD1 . PHE   B 1 291 ? 29.02838  -8.88155  -4.82248  1.000 33.68120 ?  291 PHE   B CD1 1 
ATOM   4559 C CD2 . PHE   B 1 291 ? 29.12989  -6.59009  -4.13640  1.000 33.41774 ?  291 PHE   B CD2 1 
ATOM   4560 C CE1 . PHE   B 1 291 ? 30.19345  -8.72601  -5.55486  1.000 34.62942 ?  291 PHE   B CE1 1 
ATOM   4561 C CE2 . PHE   B 1 291 ? 30.30322  -6.42554  -4.87879  1.000 40.12500 ?  291 PHE   B CE2 1 
ATOM   4562 C CZ  . PHE   B 1 291 ? 30.82678  -7.50137  -5.58655  1.000 37.64787 ?  291 PHE   B CZ  1 
ATOM   4563 N N   . THR   B 1 292 ? 24.09038  -9.24815  -3.51964  1.000 28.51818 ?  292 THR   B N   1 
ATOM   4564 C CA  . THR   B 1 292 ? 23.08752  -9.81220  -2.62748  1.000 28.54813 ?  292 THR   B CA  1 
ATOM   4565 C C   . THR   B 1 292 ? 23.75944  -10.67765 -1.55481  1.000 28.74696 ?  292 THR   B C   1 
ATOM   4566 O O   . THR   B 1 292 ? 24.92430  -11.06298 -1.68659  1.000 30.13638 ?  292 THR   B O   1 
ATOM   4567 C CB  . THR   B 1 292 ? 22.07495  -10.65409 -3.39836  1.000 32.52268 ?  292 THR   B CB  1 
ATOM   4568 O OG1 . THR   B 1 292 ? 22.71360  -11.85069 -3.88113  1.000 35.40645 ?  292 THR   B OG1 1 
ATOM   4569 C CG2 . THR   B 1 292 ? 21.44327  -9.85440  -4.55817  1.000 32.00825 ?  292 THR   B CG2 1 
ATOM   4570 N N   . PRO   B 1 293 ? 23.04848  -10.97948 -0.47092  1.000 26.92863 ?  293 PRO   B N   1 
ATOM   4571 C CA  . PRO   B 1 293 ? 23.56497  -11.97633 0.48383   1.000 26.43335 ?  293 PRO   B CA  1 
ATOM   4572 C C   . PRO   B 1 293 ? 23.94702  -13.29445 -0.16989  1.000 31.50361 ?  293 PRO   B C   1 
ATOM   4573 O O   . PRO   B 1 293 ? 24.96413  -13.89379 0.21318   1.000 32.18624 ?  293 PRO   B O   1 
ATOM   4574 C CB  . PRO   B 1 293 ? 22.39503  -12.14919 1.45344   1.000 28.87419 ?  293 PRO   B CB  1 
ATOM   4575 C CG  . PRO   B 1 293 ? 21.76495  -10.75149 1.49736   1.000 25.80670 ?  293 PRO   B CG  1 
ATOM   4576 C CD  . PRO   B 1 293 ? 21.88389  -10.24629 0.06448   1.000 28.16091 ?  293 PRO   B CD  1 
ATOM   4577 N N   . PHE   B 1 294 ? 23.16309  -13.73851 -1.16006  1.000 30.17303 ?  294 PHE   B N   1 
ATOM   4578 C CA  . PHE   B 1 294 ? 23.46675  -14.98639 -1.86049  1.000 35.11485 ?  294 PHE   B CA  1 
ATOM   4579 C C   . PHE   B 1 294 ? 24.75877  -14.85456 -2.64992  1.000 36.09271 ?  294 PHE   B C   1 
ATOM   4580 O O   . PHE   B 1 294 ? 25.58557  -15.77397 -2.65773  1.000 36.46195 ?  294 PHE   B O   1 
ATOM   4581 C CB  . PHE   B 1 294 ? 22.29163  -15.37939 -2.76924  1.000 33.79585 ?  294 PHE   B CB  1 
ATOM   4582 C CG  . PHE   B 1 294 ? 22.64178  -16.39685 -3.84911  1.000 42.79562 ?  294 PHE   B CG  1 
ATOM   4583 C CD1 . PHE   B 1 294 ? 22.44246  -17.75602 -3.64363  1.000 48.53537 ?  294 PHE   B CD1 1 
ATOM   4584 C CD2 . PHE   B 1 294 ? 23.13431  -15.97815 -5.08431  1.000 42.95752 ?  294 PHE   B CD2 1 
ATOM   4585 C CE1 . PHE   B 1 294 ? 22.75878  -18.68199 -4.63834  1.000 42.79349 ?  294 PHE   B CE1 1 
ATOM   4586 C CE2 . PHE   B 1 294 ? 23.46074  -16.89211 -6.06479  1.000 48.11938 ?  294 PHE   B CE2 1 
ATOM   4587 C CZ  . PHE   B 1 294 ? 23.26841  -18.24772 -5.83939  1.000 43.94509 ?  294 PHE   B CZ  1 
ATOM   4588 N N   . ASP   B 1 295 ? 24.94828  -13.71731 -3.32646  1.000 35.78576 ?  295 ASP   B N   1 
ATOM   4589 C CA  . ASP   B 1 295 ? 26.19473  -13.48749 -4.04248  1.000 35.65604 ?  295 ASP   B CA  1 
ATOM   4590 C C   . ASP   B 1 295 ? 27.38561  -13.63152 -3.10198  1.000 37.50566 ?  295 ASP   B C   1 
ATOM   4591 O O   . ASP   B 1 295 ? 28.35971  -14.33263 -3.41732  1.000 41.23721 ?  295 ASP   B O   1 
ATOM   4592 C CB  . ASP   B 1 295 ? 26.18301  -12.10385 -4.71210  1.000 32.24760 ?  295 ASP   B CB  1 
ATOM   4593 C CG  . ASP   B 1 295 ? 25.06169  -11.94925 -5.75373  1.000 38.67278 ?  295 ASP   B CG  1 
ATOM   4594 O OD1 . ASP   B 1 295 ? 24.52103  -12.97995 -6.23816  1.000 42.20163 ?  295 ASP   B OD1 1 
ATOM   4595 O OD2 . ASP   B 1 295 ? 24.72290  -10.79002 -6.10003  1.000 32.15499 -1 295 ASP   B OD2 1 
ATOM   4596 N N   . VAL   B 1 296 ? 27.29648  -13.03246 -1.90370  1.000 32.34808 ?  296 VAL   B N   1 
ATOM   4597 C CA  . VAL   B 1 296 ? 28.41012  -13.08587 -0.95868  1.000 31.83798 ?  296 VAL   B CA  1 
ATOM   4598 C C   . VAL   B 1 296 ? 28.61479  -14.50356 -0.42447  1.000 37.63457 ?  296 VAL   B C   1 
ATOM   4599 O O   . VAL   B 1 296 ? 29.75163  -14.96898 -0.28773  1.000 40.07543 ?  296 VAL   B O   1 
ATOM   4600 C CB  . VAL   B 1 296 ? 28.19686  -12.08984 0.19821   1.000 32.70960 ?  296 VAL   B CB  1 
ATOM   4601 C CG1 . VAL   B 1 296 ? 29.32257  -12.24265 1.22863   1.000 34.42839 ?  296 VAL   B CG1 1 
ATOM   4602 C CG2 . VAL   B 1 296 ? 28.17705  -10.68219 -0.31677  1.000 28.91617 ?  296 VAL   B CG2 1 
ATOM   4603 N N   . VAL   B 1 297 ? 27.53251  -15.18730 -0.05319  1.000 35.71010 ?  297 VAL   B N   1 
ATOM   4604 C CA  . VAL   B 1 297 ? 27.66675  -16.54323 0.48641   1.000 36.76564 ?  297 VAL   B CA  1 
ATOM   4605 C C   . VAL   B 1 297 ? 28.30495  -17.45544 -0.54853  1.000 42.59284 ?  297 VAL   B C   1 
ATOM   4606 O O   . VAL   B 1 297 ? 29.22865  -18.22419 -0.24990  1.000 39.24903 ?  297 VAL   B O   1 
ATOM   4607 C CB  . VAL   B 1 297 ? 26.29843  -17.08269 0.93593   1.000 34.63532 ?  297 VAL   B CB  1 
ATOM   4608 C CG1 . VAL   B 1 297 ? 26.34753  -18.59013 1.09257   1.000 36.19610 ?  297 VAL   B CG1 1 
ATOM   4609 C CG2 . VAL   B 1 297 ? 25.89209  -16.43172 2.25348   1.000 37.28839 ?  297 VAL   B CG2 1 
ATOM   4610 N N   . ARG   B 1 298 ? 27.82518  -17.36561 -1.78781  1.000 37.53685 ?  298 ARG   B N   1 
ATOM   4611 C CA  . ARG   B 1 298 ? 28.34413  -18.19260 -2.86761  1.000 43.30259 ?  298 ARG   B CA  1 
ATOM   4612 C C   . ARG   B 1 298 ? 29.81840  -17.91815 -3.08732  1.000 45.27192 ?  298 ARG   B C   1 
ATOM   4613 O O   . ARG   B 1 298 ? 30.62091  -18.84544 -3.24556  1.000 43.38232 ?  298 ARG   B O   1 
ATOM   4614 C CB  . ARG   B 1 298 ? 27.53213  -17.92863 -4.14012  1.000 40.27018 ?  298 ARG   B CB  1 
ATOM   4615 C CG  . ARG   B 1 298 ? 28.01625  -18.66123 -5.39515  1.000 49.61572 ?  298 ARG   B CG  1 
ATOM   4616 C CD  . ARG   B 1 298 ? 27.02088  -18.50640 -6.54013  1.000 47.75863 ?  298 ARG   B CD  1 
ATOM   4617 N NE  . ARG   B 1 298 ? 27.19575  -19.51216 -7.58729  1.000 54.70938 ?  298 ARG   B NE  1 
ATOM   4618 C CZ  . ARG   B 1 298 ? 27.95065  -19.34381 -8.66554  1.000 50.56204 ?  298 ARG   B CZ  1 
ATOM   4619 N NH1 . ARG   B 1 298 ? 28.65292  -18.23628 -8.85098  1.000 47.78794 ?  298 ARG   B NH1 1 
ATOM   4620 N NH2 . ARG   B 1 298 ? 27.99444  -20.30661 -9.58642  1.000 51.69175 ?  298 ARG   B NH2 1 
ATOM   4621 N N   . GLN   B 1 299 ? 30.21012  -16.65453 -3.04123  1.000 45.20198 ?  299 GLN   B N   1 
ATOM   4622 C CA  . GLN   B 1 299 ? 31.59760  -16.37308 -3.33446  1.000 42.52188 ?  299 GLN   B CA  1 
ATOM   4623 C C   . GLN   B 1 299 ? 32.51494  -16.67602 -2.15471  1.000 47.25419 ?  299 GLN   B C   1 
ATOM   4624 O O   . GLN   B 1 299 ? 33.66881  -17.05641 -2.37281  1.000 49.37433 ?  299 GLN   B O   1 
ATOM   4625 C CB  . GLN   B 1 299 ? 31.73326  -14.92638 -3.79092  1.000 40.49441 ?  299 GLN   B CB  1 
ATOM   4626 C CG  . GLN   B 1 299 ? 33.01300  -14.67457 -4.47434  1.000 39.38323 ?  299 GLN   B CG  1 
ATOM   4627 C CD  . GLN   B 1 299 ? 33.04766  -13.35462 -5.16498  1.000 33.47141 ?  299 GLN   B CD  1 
ATOM   4628 O OE1 . GLN   B 1 299 ? 34.09709  -12.72199 -5.25059  1.000 34.42786 ?  299 GLN   B OE1 1 
ATOM   4629 N NE2 . GLN   B 1 299 ? 31.89775  -12.92332 -5.69171  1.000 36.87665 ?  299 GLN   B NE2 1 
ATOM   4630 N N   . CYS   B 1 300 ? 32.02135  -16.56466 -0.91335  1.000 47.42971 ?  300 CYS   B N   1 
ATOM   4631 C CA  . CYS   B 1 300 ? 32.85074  -16.60112 0.28778   1.000 48.77730 ?  300 CYS   B CA  1 
ATOM   4632 C C   . CYS   B 1 300 ? 32.60491  -17.83416 1.15141   1.000 54.84722 ?  300 CYS   B C   1 
ATOM   4633 O O   . CYS   B 1 300 ? 32.89587  -17.80428 2.35277   1.000 57.79377 ?  300 CYS   B O   1 
ATOM   4634 C CB  . CYS   B 1 300 ? 32.62042  -15.35180 1.14462   1.000 47.17441 ?  300 CYS   B CB  1 
ATOM   4635 S SG  . CYS   B 1 300 ? 33.07309  -13.76190 0.41656   1.000 48.91071 ?  300 CYS   B SG  1 
ATOM   4636 N N   . SER   B 1 301 ? 32.06730  -18.90816 0.58204   1.000 53.25481 ?  301 SER   B N   1 
ATOM   4637 C CA  . SER   B 1 301 ? 31.76777  -20.09889 1.37126   1.000 56.74195 ?  301 SER   B CA  1 
ATOM   4638 C C   . SER   B 1 301 ? 33.05682  -20.80763 1.77365   1.000 58.33239 ?  301 SER   B C   1 
ATOM   4639 O O   . SER   B 1 301 ? 33.77002  -21.34567 0.91875   1.000 57.20821 ?  301 SER   B O   1 
ATOM   4640 C CB  . SER   B 1 301 ? 30.86972  -21.03877 0.57624   1.000 57.83190 ?  301 SER   B CB  1 
ATOM   4641 O OG  . SER   B 1 301 ? 31.45097  -21.32227 -0.68602  1.000 60.52346 ?  301 SER   B OG  1 
ATOM   4642 N N   . GLY   B 1 302 ? 33.34601  -20.82443 3.07409   1.000 58.57862 ?  302 GLY   B N   1 
ATOM   4643 C CA  . GLY   B 1 302 ? 34.54843  -21.46033 3.58127   1.000 56.94295 ?  302 GLY   B CA  1 
ATOM   4644 C C   . GLY   B 1 302 ? 35.61348  -20.46040 3.99113   1.000 59.36972 ?  302 GLY   B C   1 
ATOM   4645 O O   . GLY   B 1 302 ? 36.02027  -19.60695 3.20027   1.000 57.58867 ?  302 GLY   B O   1 
HETATM 4646 C C   . ACE   C 2 1   ? -11.30281 -20.67684 1.69038   1.000 46.20699 ?  1   ACE   C C   1 
HETATM 4647 O O   . ACE   C 2 1   ? -11.22239 -20.86278 0.51155   1.000 47.02104 ?  1   ACE   C O   1 
HETATM 4648 C CH3 . ACE   C 2 1   ? -12.52466 -21.12639 2.49208   1.000 47.52352 ?  1   ACE   C CH3 1 
HETATM 4649 N N   . ABA   C 2 2   ? -10.23006 -20.01681 2.37545   1.000 43.34876 ?  2   ABA   C N   1 
HETATM 4650 C CA  . ABA   C 2 2   ? -9.07870  -19.61182 1.61978   1.000 38.05580 ?  2   ABA   C CA  1 
HETATM 4651 C C   . ABA   C 2 2   ? -8.31084  -20.86982 1.22310   1.000 36.92490 ?  2   ABA   C C   1 
HETATM 4652 O O   . ABA   C 2 2   ? -8.49781  -21.92995 1.74606   1.000 44.84131 ?  2   ABA   C O   1 
HETATM 4653 C CB  . ABA   C 2 2   ? -8.19043  -18.71878 2.48310   1.000 40.41188 ?  2   ABA   C CB  1 
HETATM 4654 C CG  . ABA   C 2 2   ? -7.73809  -19.40658 3.76970   1.000 41.73138 ?  2   ABA   C CG  1 
HETATM 4655 N N   . DTY   C 2 3   ? -7.31799  -20.73948 0.20043   1.000 32.64723 ?  3   DTY   C N   1 
HETATM 4656 C CA  . DTY   C 2 3   ? -6.52663  -21.85855 -0.23615  1.000 29.21410 ?  3   DTY   C CA  1 
HETATM 4657 C C   . DTY   C 2 3   ? -6.93171  -22.30091 -1.63653  1.000 32.95623 ?  3   DTY   C C   1 
HETATM 4658 O O   . DTY   C 2 3   ? -7.59823  -21.58806 -2.32648  1.000 27.87958 ?  3   DTY   C O   1 
HETATM 4659 C CB  . DTY   C 2 3   ? -5.08050  -21.38688 -0.24396  1.000 31.94767 ?  3   DTY   C CB  1 
HETATM 4660 C CG  . DTY   C 2 3   ? -4.65497  -21.22577 1.22453   1.000 36.57016 ?  3   DTY   C CG  1 
HETATM 4661 C CD1 . DTY   C 2 3   ? -4.24461  -22.33853 1.94224   1.000 38.81090 ?  3   DTY   C CD1 1 
HETATM 4662 C CD2 . DTY   C 2 3   ? -4.70612  -19.97812 1.83660   1.000 41.11824 ?  3   DTY   C CD2 1 
HETATM 4663 C CE1 . DTY   C 2 3   ? -3.87424  -22.20528 3.27480   1.000 41.68297 ?  3   DTY   C CE1 1 
HETATM 4664 C CE2 . DTY   C 2 3   ? -4.33792  -19.85117 3.16570   1.000 39.11500 ?  3   DTY   C CE2 1 
HETATM 4665 C CZ  . DTY   C 2 3   ? -3.92236  -20.96088 3.88615   1.000 41.34624 ?  3   DTY   C CZ  1 
HETATM 4666 O OH  . DTY   C 2 3   ? -3.55036  -20.81739 5.23773   1.000 42.88817 ?  3   DTY   C OH  1 
ATOM   4667 N N   . LEU   C 2 4   ? -6.46925  -23.59073 -2.06893  1.000 30.57925 ?  4   LEU   C N   1 
ATOM   4668 C CA  . LEU   C 2 4   ? -6.83143  -24.09891 -3.39751  1.000 29.95409 ?  4   LEU   C CA  1 
ATOM   4669 C C   . LEU   C 2 4   ? -8.34345  -24.17443 -3.38429  1.000 27.44347 ?  4   LEU   C C   1 
ATOM   4670 O O   . LEU   C 2 4   ? -8.95864  -24.60012 -2.44163  1.000 27.74956 ?  4   LEU   C O   1 
ATOM   4671 C CB  . LEU   C 2 4   ? -6.16878  -25.44213 -3.63849  1.000 29.24133 ?  4   LEU   C CB  1 
ATOM   4672 C CG  . LEU   C 2 4   ? -4.91799  -25.41203 -4.52342  1.000 34.10550 ?  4   LEU   C CG  1 
ATOM   4673 C CD1 . LEU   C 2 4   ? -4.12291  -24.12336 -4.55669  1.000 35.16963 ?  4   LEU   C CD1 1 
ATOM   4674 C CD2 . LEU   C 2 4   ? -3.98204  -26.59481 -4.27920  1.000 31.32307 ?  4   LEU   C CD2 1 
HETATM 4675 C C30 . A1AMA C 2 5   ? -10.52507 -23.80178 -4.34921  1.000 28.29779 ?  5   A1AMA C C30 1 
HETATM 4676 C C31 . A1AMA C 2 5   ? -11.13966 -22.44646 -4.73983  1.000 25.17936 ?  5   A1AMA C C31 1 
HETATM 4677 C C32 . A1AMA C 2 5   ? -11.07426 -21.57013 -3.52105  1.000 35.80479 ?  5   A1AMA C C32 1 
HETATM 4678 C C33 . A1AMA C 2 5   ? -12.02545 -20.41504 -3.72413  1.000 32.31816 ?  5   A1AMA C C33 1 
HETATM 4679 C C36 . A1AMA C 2 5   ? -11.34726 -24.91568 -5.00843  1.000 36.68614 ?  5   A1AMA C C36 1 
HETATM 4680 C C37 . A1AMA C 2 5   ? -10.52747 -26.15569 -5.45838  1.000 26.11992 ?  5   A1AMA C C37 1 
HETATM 4681 C C39 . A1AMA C 2 5   ? -11.41557 -28.82076 -5.79013  1.000 25.23355 ?  5   A1AMA C C39 1 
HETATM 4682 N N29 . A1AMA C 2 5   ? -9.07457  -23.76400 -4.54898  1.000 25.51769 ?  5   A1AMA C N29 1 
HETATM 4683 N N34 . A1AMA C 2 5   ? -13.10764 -20.31588 -2.78322  1.000 29.93367 ?  5   A1AMA C N34 1 
HETATM 4684 O O35 . A1AMA C 2 5   ? -11.85622 -19.64948 -4.64167  1.000 26.72205 ?  5   A1AMA C O35 1 
HETATM 4685 O O40 . A1AMA C 2 5   ? -12.90742 -26.88236 -4.47289  1.000 31.21782 ?  5   A1AMA C O40 1 
HETATM 4686 O O41 . A1AMA C 2 5   ? -12.71931 -26.76518 -7.13206  1.000 26.22129 ?  5   A1AMA C O41 1 
HETATM 4687 S S38 . A1AMA C 2 5   ? -11.95820 -27.10721 -5.76309  1.000 25.86019 ?  5   A1AMA C S38 1 
HETATM 4688 C C   . ACE   D 2 1   ? 22.32848  7.59879   -26.32587 1.000 44.20974 ?  1   ACE   D C   1 
HETATM 4689 O O   . ACE   D 2 1   ? 21.82969  6.52200   -26.21562 1.000 43.31512 ?  1   ACE   D O   1 
HETATM 4690 C CH3 . ACE   D 2 1   ? 23.51887  7.81097   -27.26508 1.000 45.00519 ?  1   ACE   D CH3 1 
HETATM 4691 N N   . ABA   D 2 2   ? 21.81103  8.70534   -25.55107 1.000 44.50059 ?  2   ABA   D N   1 
HETATM 4692 C CA  . ABA   D 2 2   ? 20.67881  8.45836   -24.69125 1.000 35.14970 ?  2   ABA   D CA  1 
HETATM 4693 C C   . ABA   D 2 2   ? 19.44398  8.21750   -25.58134 1.000 38.13885 ?  2   ABA   D C   1 
HETATM 4694 O O   . ABA   D 2 2   ? 19.43148  8.49726   -26.74108 1.000 38.08954 ?  2   ABA   D O   1 
HETATM 4695 C CB  . ABA   D 2 2   ? 20.49350  9.60541   -23.70133 1.000 39.25820 ?  2   ABA   D CB  1 
HETATM 4696 C CG  . ABA   D 2 2   ? 20.02172  10.89919  -24.36441 1.000 40.29920 ?  2   ABA   D CG  1 
HETATM 4697 N N   . DTY   D 2 3   ? 18.26822  7.59267   -25.01164 1.000 32.50915 ?  3   DTY   D N   1 
HETATM 4698 C CA  . DTY   D 2 3   ? 17.09243  7.32382   -25.82154 1.000 30.59439 ?  3   DTY   D CA  1 
HETATM 4699 C C   . DTY   D 2 3   ? 16.95074  5.82158   -26.04066 1.000 33.93330 ?  3   DTY   D C   1 
HETATM 4700 O O   . DTY   D 2 3   ? 17.51355  5.04040   -25.34265 1.000 32.51911 ?  3   DTY   D O   1 
HETATM 4701 C CB  . DTY   D 2 3   ? 15.86230  7.85981   -25.09323 1.000 33.04016 ?  3   DTY   D CB  1 
HETATM 4702 C CG  . DTY   D 2 3   ? 15.89383  9.39087   -25.15337 1.000 31.07493 ?  3   DTY   D CG  1 
HETATM 4703 C CD1 . DTY   D 2 3   ? 16.52733  10.10314  -24.15491 1.000 34.50649 ?  3   DTY   D CD1 1 
HETATM 4704 C CD2 . DTY   D 2 3   ? 15.31610  10.04952  -26.22502 1.000 34.71621 ?  3   DTY   D CD2 1 
HETATM 4705 C CE1 . DTY   D 2 3   ? 16.57645  11.48264  -24.20382 1.000 36.70998 ?  3   DTY   D CE1 1 
HETATM 4706 C CE2 . DTY   D 2 3   ? 15.35793  11.43852  -26.27255 1.000 35.27937 ?  3   DTY   D CE2 1 
HETATM 4707 C CZ  . DTY   D 2 3   ? 15.99403  12.14865  -25.26458 1.000 36.44385 ?  3   DTY   D CZ  1 
HETATM 4708 O OH  . DTY   D 2 3   ? 16.05000  13.54868  -25.30078 1.000 38.74224 ?  3   DTY   D OH  1 
ATOM   4709 N N   . LEU   D 2 4   ? 16.11922  5.35493   -27.11022 1.000 28.83317 ?  4   LEU   D N   1 
ATOM   4710 C CA  . LEU   D 2 4   ? 15.95337  3.94804   -27.37890 1.000 31.65287 ?  4   LEU   D CA  1 
ATOM   4711 C C   . LEU   D 2 4   ? 17.32646  3.46569   -27.80692 1.000 32.95154 ?  4   LEU   D C   1 
ATOM   4712 O O   . LEU   D 2 4   ? 18.00594  4.15559   -28.50994 1.000 33.21662 ?  4   LEU   D O   1 
ATOM   4713 C CB  . LEU   D 2 4   ? 14.98941  3.77362   -28.54348 1.000 31.52758 ?  4   LEU   D CB  1 
ATOM   4714 C CG  . LEU   D 2 4   ? 13.54668  3.41829   -28.21132 1.000 39.09987 ?  4   LEU   D CG  1 
ATOM   4715 C CD1 . LEU   D 2 4   ? 13.11774  3.35667   -26.75419 1.000 32.33055 ?  4   LEU   D CD1 1 
ATOM   4716 C CD2 . LEU   D 2 4   ? 12.51081  3.98246   -29.19457 1.000 34.07457 ?  4   LEU   D CD2 1 
HETATM 4717 C C30 . A1AMA D 2 5   ? 19.08858  1.66160   -27.61763 1.000 28.43142 ?  5   A1AMA D C30 1 
HETATM 4718 C C31 . A1AMA D 2 5   ? 19.93678  1.56217   -26.33865 1.000 26.08177 ?  5   A1AMA D C31 1 
HETATM 4719 C C32 . A1AMA D 2 5   ? 20.56841  2.88602   -25.96724 1.000 33.72839 ?  5   A1AMA D C32 1 
HETATM 4720 C C33 . A1AMA D 2 5   ? 21.70628  2.67184   -24.97603 1.000 32.91787 ?  5   A1AMA D C33 1 
HETATM 4721 C C36 . A1AMA D 2 5   ? 18.86427  0.29194   -28.24089 1.000 26.91905 ?  5   A1AMA D C36 1 
HETATM 4722 C C37 . A1AMA D 2 5   ? 18.24112  0.53124   -29.60992 1.000 33.35825 ?  5   A1AMA D C37 1 
HETATM 4723 C C39 . A1AMA D 2 5   ? 18.32194  0.09530   -32.43249 1.000 30.54403 ?  5   A1AMA D C39 1 
HETATM 4724 N N29 . A1AMA D 2 5   ? 17.79092  2.20709   -27.27960 1.000 28.90073 ?  5   A1AMA D N29 1 
HETATM 4725 N N34 . A1AMA D 2 5   ? 22.92849  3.41167   -25.11105 1.000 34.19586 ?  5   A1AMA D N34 1 
HETATM 4726 O O35 . A1AMA D 2 5   ? 21.54773  1.91098   -24.08487 1.000 28.12805 ?  5   A1AMA D O35 1 
HETATM 4727 O O40 . A1AMA D 2 5   ? 19.89337  -1.52738  -30.69668 1.000 32.04779 ?  5   A1AMA D O40 1 
HETATM 4728 O O41 . A1AMA D 2 5   ? 20.55636  1.12359   -31.09770 1.000 30.42040 ?  5   A1AMA D O41 1 
HETATM 4729 S S38 . A1AMA D 2 5   ? 19.37761  0.01227   -30.93694 1.000 28.62182 ?  5   A1AMA D S38 1 
HETATM 4730 O O   . HOH   E 3 .   ? 1.67249   1.01640   -28.97508 1.000 40.74802 ?  401 HOH   A O   1 
HETATM 4731 O O   . HOH   E 3 .   ? -7.26197  -3.39159  -5.10544  1.000 44.62063 ?  402 HOH   A O   1 
HETATM 4732 O O   . HOH   E 3 .   ? -23.15234 -36.58101 -12.97612 1.000 48.17258 ?  403 HOH   A O   1 
HETATM 4733 O O   . HOH   E 3 .   ? -9.06195  -7.55534  -23.18160 1.000 49.89518 ?  404 HOH   A O   1 
HETATM 4734 O O   . HOH   E 3 .   ? -3.45731  21.07466  -4.28095  1.000 48.73033 ?  405 HOH   A O   1 
HETATM 4735 O O   . HOH   E 3 .   ? -20.45276 -11.65255 -30.29019 1.000 50.31899 ?  406 HOH   A O   1 
HETATM 4736 O O   . HOH   E 3 .   ? -4.21509  7.73752   -4.05926  1.000 46.01757 ?  407 HOH   A O   1 
HETATM 4737 O O   . HOH   E 3 .   ? -8.66234  7.36444   -7.00545  1.000 43.81186 ?  408 HOH   A O   1 
HETATM 4738 O O   . HOH   E 3 .   ? 0.87730   -33.05100 0.84133   1.000 44.86202 ?  409 HOH   A O   1 
HETATM 4739 O O   . HOH   E 3 .   ? 1.25813   -18.37021 -20.98520 1.000 39.95166 ?  410 HOH   A O   1 
HETATM 4740 O O   . HOH   E 3 .   ? -29.374   -1.829    -12.239   1.000 40.31513 ?  411 HOH   A O   1 
HETATM 4741 O O   . HOH   E 3 .   ? -16.56904 -41.05087 -24.41973 1.000 37.30464 ?  412 HOH   A O   1 
HETATM 4742 O O   . HOH   E 3 .   ? -6.86830  18.09968  -26.27279 1.000 40.46170 ?  413 HOH   A O   1 
HETATM 4743 O O   . HOH   E 3 .   ? 3.98978   -25.16197 -4.58718  1.000 43.33432 ?  414 HOH   A O   1 
HETATM 4744 O O   . HOH   E 3 .   ? -6.29154  -42.26130 -9.08902  1.000 48.00518 ?  415 HOH   A O   1 
HETATM 4745 O O   . HOH   E 3 .   ? -12.05405 -12.78502 -28.54640 1.000 43.52796 ?  416 HOH   A O   1 
HETATM 4746 O O   . HOH   E 3 .   ? -13.45904 18.45828  -27.99757 1.000 34.78678 ?  417 HOH   A O   1 
HETATM 4747 O O   . HOH   E 3 .   ? -20.87748 16.36076  -12.38790 1.000 48.03987 ?  418 HOH   A O   1 
HETATM 4748 O O   . HOH   E 3 .   ? -6.17709  12.31348  -4.20287  1.000 47.09351 ?  419 HOH   A O   1 
HETATM 4749 O O   . HOH   E 3 .   ? -16.39808 -21.41054 -16.37596 1.000 25.41553 ?  420 HOH   A O   1 
HETATM 4750 O O   . HOH   E 3 .   ? -18.38136 -9.35723  -28.77399 1.000 50.51309 ?  421 HOH   A O   1 
HETATM 4751 O O   . HOH   E 3 .   ? -13.35234 7.77558   -31.95465 1.000 38.75161 ?  422 HOH   A O   1 
HETATM 4752 O O   . HOH   E 3 .   ? -9.81023  19.08038  -29.96232 1.000 46.72019 ?  423 HOH   A O   1 
HETATM 4753 O O   . HOH   E 3 .   ? -23.60358 -5.20488  -13.16243 1.000 39.74835 ?  424 HOH   A O   1 
HETATM 4754 O O   . HOH   E 3 .   ? 1.45400   0.14902   -15.89401 1.000 35.17108 ?  425 HOH   A O   1 
HETATM 4755 O O   . HOH   E 3 .   ? 3.51165   -1.08919  -13.26341 1.000 46.14012 ?  426 HOH   A O   1 
HETATM 4756 O O   . HOH   E 3 .   ? -10.98962 -7.49995  -9.96476  1.000 31.18313 ?  427 HOH   A O   1 
HETATM 4757 O O   . HOH   E 3 .   ? -19.52862 -18.39996 -7.31060  1.000 33.31044 ?  428 HOH   A O   1 
HETATM 4758 O O   . HOH   E 3 .   ? -15.68675 -4.53295  -15.46789 1.000 42.58245 ?  429 HOH   A O   1 
HETATM 4759 O O   . HOH   E 3 .   ? -12.24448 -3.28984  -7.88075  1.000 49.33933 ?  430 HOH   A O   1 
HETATM 4760 O O   . HOH   E 3 .   ? 3.24161   8.36301   -25.92378 1.000 47.76273 ?  431 HOH   A O   1 
HETATM 4761 O O   . HOH   E 3 .   ? 2.16406   2.81783   -8.89453  1.000 35.85587 ?  432 HOH   A O   1 
HETATM 4762 O O   . HOH   E 3 .   ? 1.85461   -4.71282  -27.34739 1.000 29.87134 ?  433 HOH   A O   1 
HETATM 4763 O O   . HOH   E 3 .   ? -19.57196 -25.52845 -32.63948 1.000 35.41506 ?  434 HOH   A O   1 
HETATM 4764 O O   . HOH   E 3 .   ? -21.85486 13.73445  -11.64892 1.000 44.96423 ?  435 HOH   A O   1 
HETATM 4765 O O   . HOH   E 3 .   ? 1.01706   -40.17346 -16.05158 1.000 39.43970 ?  436 HOH   A O   1 
HETATM 4766 O O   . HOH   E 3 .   ? -1.79687  -2.50636  -17.68208 1.000 36.87750 ?  437 HOH   A O   1 
HETATM 4767 O O   . HOH   E 3 .   ? 0.21397   -1.96253  -21.42835 1.000 31.73842 ?  438 HOH   A O   1 
HETATM 4768 O O   . HOH   E 3 .   ? -4.93880  -18.23474 -22.00555 1.000 30.92362 ?  439 HOH   A O   1 
HETATM 4769 O O   . HOH   E 3 .   ? -16.96565 -28.65699 -8.77559  1.000 29.56439 ?  440 HOH   A O   1 
HETATM 4770 O O   . HOH   E 3 .   ? -16.68528 9.07898   -10.66879 1.000 42.13775 ?  441 HOH   A O   1 
HETATM 4771 O O   . HOH   E 3 .   ? -28.73433 2.97048   -21.05842 1.000 37.59475 ?  442 HOH   A O   1 
HETATM 4772 O O   . HOH   E 3 .   ? 0.55339   -23.96028 -25.38233 1.000 49.43833 ?  443 HOH   A O   1 
HETATM 4773 O O   . HOH   E 3 .   ? -9.07746  18.26884  -13.02167 1.000 35.92518 ?  444 HOH   A O   1 
HETATM 4774 O O   . HOH   E 3 .   ? 9.89558   14.28788  -16.50989 1.000 37.35852 ?  445 HOH   A O   1 
HETATM 4775 O O   . HOH   E 3 .   ? -25.40206 -23.80031 -18.78128 1.000 38.73513 ?  446 HOH   A O   1 
HETATM 4776 O O   . HOH   E 3 .   ? -26.40014 -35.49084 -18.36547 1.000 49.55334 ?  447 HOH   A O   1 
HETATM 4777 O O   . HOH   E 3 .   ? -3.75212  7.43735   -28.58922 1.000 37.97781 ?  448 HOH   A O   1 
HETATM 4778 O O   . HOH   E 3 .   ? -19.09569 16.81483  -23.52678 1.000 26.33242 ?  449 HOH   A O   1 
HETATM 4779 O O   . HOH   E 3 .   ? -12.25379 -4.72623  -22.42179 1.000 35.65225 ?  450 HOH   A O   1 
HETATM 4780 O O   . HOH   E 3 .   ? -3.45828  -38.39750 1.04691   1.000 38.75187 ?  451 HOH   A O   1 
HETATM 4781 O O   . HOH   E 3 .   ? -14.24307 -7.41217  -20.75301 1.000 36.15107 ?  452 HOH   A O   1 
HETATM 4782 O O   . HOH   E 3 .   ? -20.69186 -23.70358 -26.68595 1.000 33.32653 ?  453 HOH   A O   1 
HETATM 4783 O O   . HOH   E 3 .   ? -11.23829 14.29925  -32.88730 1.000 43.08191 ?  454 HOH   A O   1 
HETATM 4784 O O   . HOH   E 3 .   ? 1.10099   -38.89308 -20.33152 1.000 43.57369 ?  455 HOH   A O   1 
HETATM 4785 O O   . HOH   E 3 .   ? -20.48356 -42.07633 -22.12439 1.000 43.43204 ?  456 HOH   A O   1 
HETATM 4786 O O   . HOH   E 3 .   ? -10.46298 4.40991   -26.55873 1.000 33.42941 ?  457 HOH   A O   1 
HETATM 4787 O O   . HOH   E 3 .   ? -20.43189 -8.33988  -13.05215 1.000 36.09936 ?  458 HOH   A O   1 
HETATM 4788 O O   . HOH   E 3 .   ? -6.92182  -36.29857 2.48589   1.000 44.56681 ?  459 HOH   A O   1 
HETATM 4789 O O   . HOH   E 3 .   ? -13.84082 -26.76101 -33.68871 1.000 36.92271 ?  460 HOH   A O   1 
HETATM 4790 O O   . HOH   E 3 .   ? 3.56261   -17.41734 -14.00872 1.000 39.58182 ?  461 HOH   A O   1 
HETATM 4791 O O   . HOH   E 3 .   ? -10.31081 -37.77893 -29.77918 1.000 38.61233 ?  462 HOH   A O   1 
HETATM 4792 O O   . HOH   E 3 .   ? 0.08368   22.59756  -19.91332 1.000 40.26518 ?  463 HOH   A O   1 
HETATM 4793 O O   . HOH   E 3 .   ? 3.23126   -21.07417 -10.03125 1.000 29.25898 ?  464 HOH   A O   1 
HETATM 4794 O O   . HOH   E 3 .   ? -0.30151  0.22118   -30.49641 1.000 40.84088 ?  465 HOH   A O   1 
HETATM 4795 O O   . HOH   E 3 .   ? 0.48484   -3.27039  -18.82904 1.000 37.20208 ?  466 HOH   A O   1 
HETATM 4796 O O   . HOH   E 3 .   ? -3.63288  -14.75882 -10.31124 1.000 25.93683 ?  467 HOH   A O   1 
HETATM 4797 O O   . HOH   E 3 .   ? 1.06601   -9.79504  -6.43659  1.000 33.06184 ?  468 HOH   A O   1 
HETATM 4798 O O   . HOH   E 3 .   ? -15.93698 -4.52506  -17.71435 1.000 40.71637 ?  469 HOH   A O   1 
HETATM 4799 O O   . HOH   E 3 .   ? 4.07462   -28.58841 -14.80054 1.000 34.44273 ?  470 HOH   A O   1 
HETATM 4800 O O   . HOH   E 3 .   ? 2.22592   -9.75691  -18.89717 1.000 38.75319 ?  471 HOH   A O   1 
HETATM 4801 O O   . HOH   E 3 .   ? -15.12303 -29.90196 -5.26000  1.000 39.02626 ?  472 HOH   A O   1 
HETATM 4802 O O   . HOH   E 3 .   ? -4.85850  -19.83433 -28.91917 1.000 33.22940 ?  473 HOH   A O   1 
HETATM 4803 O O   . HOH   E 3 .   ? -2.98393  -25.29051 -22.94610 1.000 31.83116 ?  474 HOH   A O   1 
HETATM 4804 O O   . HOH   E 3 .   ? 2.80834   -23.50727 -8.96355  1.000 31.04842 ?  475 HOH   A O   1 
HETATM 4805 O O   . HOH   E 3 .   ? -13.97471 -30.23454 -33.23278 1.000 33.19762 ?  476 HOH   A O   1 
HETATM 4806 O O   . HOH   E 3 .   ? -19.93331 -17.11000 -4.77161  1.000 40.93211 ?  477 HOH   A O   1 
HETATM 4807 O O   . HOH   E 3 .   ? -21.20006 -30.13625 -17.85219 1.000 37.56533 ?  478 HOH   A O   1 
HETATM 4808 O O   . HOH   E 3 .   ? 7.27288   8.72563   -8.43607  1.000 36.65030 ?  479 HOH   A O   1 
HETATM 4809 O O   . HOH   E 3 .   ? 2.83371   3.40245   -6.48765  1.000 43.64263 ?  480 HOH   A O   1 
HETATM 4810 O O   . HOH   E 3 .   ? 4.75948   -36.84624 -14.25647 1.000 45.64458 ?  481 HOH   A O   1 
HETATM 4811 O O   . HOH   E 3 .   ? -8.66446  -27.99521 -27.73903 1.000 31.09149 ?  482 HOH   A O   1 
HETATM 4812 O O   . HOH   E 3 .   ? -22.45013 -28.22521 -33.84076 1.000 38.24685 ?  483 HOH   A O   1 
HETATM 4813 O O   . HOH   E 3 .   ? -4.67173  -9.18314  -1.41434  1.000 41.01628 ?  484 HOH   A O   1 
HETATM 4814 O O   . HOH   E 3 .   ? -13.88110 -40.22452 -17.95722 1.000 26.62779 ?  485 HOH   A O   1 
HETATM 4815 O O   . HOH   E 3 .   ? 3.11017   0.48034   -9.76495  1.000 38.23017 ?  486 HOH   A O   1 
HETATM 4816 O O   . HOH   E 3 .   ? 2.75738   -34.51804 -18.68917 1.000 36.23067 ?  487 HOH   A O   1 
HETATM 4817 O O   . HOH   E 3 .   ? -3.62049  -26.36555 -9.89534  1.000 26.46715 ?  488 HOH   A O   1 
HETATM 4818 O O   . HOH   E 3 .   ? -10.37412 -41.60929 -9.80082  1.000 34.61399 ?  489 HOH   A O   1 
HETATM 4819 O O   . HOH   E 3 .   ? -23.594   18.983    -20.320   1.000 39.69173 ?  490 HOH   A O   1 
HETATM 4820 O O   . HOH   E 3 .   ? -4.88429  4.91624   -5.44676  1.000 36.90388 ?  491 HOH   A O   1 
HETATM 4821 O O   . HOH   E 3 .   ? -23.50733 -19.14597 -29.61157 1.000 39.77635 ?  492 HOH   A O   1 
HETATM 4822 O O   . HOH   E 3 .   ? 4.81133   -28.45221 -3.12051  1.000 46.62504 ?  493 HOH   A O   1 
HETATM 4823 O O   . HOH   E 3 .   ? 3.10078   -0.47876  -24.06451 1.000 30.05501 ?  494 HOH   A O   1 
HETATM 4824 O O   . HOH   E 3 .   ? -2.71924  -18.56133 -0.55071  1.000 36.15190 ?  495 HOH   A O   1 
HETATM 4825 O O   . HOH   E 3 .   ? 3.33215   -35.15081 -3.43357  1.000 43.23765 ?  496 HOH   A O   1 
HETATM 4826 O O   . HOH   E 3 .   ? -22.56982 -2.01588  -12.40701 1.000 49.67404 ?  497 HOH   A O   1 
HETATM 4827 O O   . HOH   E 3 .   ? -2.51590  19.15476  -14.15899 1.000 44.25100 ?  498 HOH   A O   1 
HETATM 4828 O O   . HOH   E 3 .   ? -16.30563 -35.86466 -12.94167 1.000 25.43193 ?  499 HOH   A O   1 
HETATM 4829 O O   . HOH   E 3 .   ? -2.56930  -10.73006 -0.14144  1.000 40.31596 ?  500 HOH   A O   1 
HETATM 4830 O O   . HOH   E 3 .   ? -13.00497 2.45144   -15.23779 1.000 24.27541 ?  501 HOH   A O   1 
HETATM 4831 O O   . HOH   E 3 .   ? -2.28301  16.30804  -2.91896  1.000 46.25296 ?  502 HOH   A O   1 
HETATM 4832 O O   . HOH   E 3 .   ? 3.33059   -14.53423 -2.71733  1.000 43.02285 ?  503 HOH   A O   1 
HETATM 4833 O O   . HOH   E 3 .   ? 2.68544   -20.92154 -13.12938 1.000 32.02271 ?  504 HOH   A O   1 
HETATM 4834 O O   . HOH   E 3 .   ? 8.95319   15.22163  -18.98118 1.000 37.02138 ?  505 HOH   A O   1 
HETATM 4835 O O   . HOH   E 3 .   ? 1.35677   -4.99431  -12.74590 1.000 38.67027 ?  506 HOH   A O   1 
HETATM 4836 O O   . HOH   E 3 .   ? -16.94682 -22.58884 0.10358   1.000 43.63411 ?  507 HOH   A O   1 
HETATM 4837 O O   . HOH   E 3 .   ? -3.96532  12.18908  -27.75970 1.000 37.62377 ?  508 HOH   A O   1 
HETATM 4838 O O   . HOH   E 3 .   ? -3.14923  -12.97820 1.04228   1.000 38.60606 ?  509 HOH   A O   1 
HETATM 4839 O O   . HOH   E 3 .   ? 5.24458   2.75031   -17.93150 1.000 26.48225 ?  510 HOH   A O   1 
HETATM 4840 O O   . HOH   E 3 .   ? -18.67735 -4.07208  -18.41040 1.000 41.28598 ?  511 HOH   A O   1 
HETATM 4841 O O   . HOH   E 3 .   ? -24.29481 12.48712  -24.43889 1.000 39.65573 ?  512 HOH   A O   1 
HETATM 4842 O O   . HOH   E 3 .   ? -5.61111  -7.83411  -3.96866  1.000 37.85570 ?  513 HOH   A O   1 
HETATM 4843 O O   . HOH   E 3 .   ? -19.87093 18.79269  -15.50188 1.000 44.13062 ?  514 HOH   A O   1 
HETATM 4844 O O   . HOH   E 3 .   ? -12.757   -11.147   -4.036    1.000 36.59546 ?  515 HOH   A O   1 
HETATM 4845 O O   . HOH   E 3 .   ? 3.57196   -14.66180 -0.30102  1.000 46.07653 ?  516 HOH   A O   1 
HETATM 4846 O O   . HOH   E 3 .   ? -21.68913 -30.50213 -26.10096 1.000 39.95496 ?  517 HOH   A O   1 
HETATM 4847 O O   . HOH   E 3 .   ? -19.10357 -2.78941  -20.83415 1.000 43.57139 ?  518 HOH   A O   1 
HETATM 4848 O O   . HOH   E 3 .   ? -18.06855 -19.40966 -32.36192 1.000 37.40558 ?  519 HOH   A O   1 
HETATM 4849 O O   . HOH   E 3 .   ? -4.18673  -28.80772 -26.73639 1.000 38.49312 ?  520 HOH   A O   1 
HETATM 4850 O O   . HOH   E 3 .   ? -7.30529  -1.73225  -19.52408 1.000 33.67479 ?  521 HOH   A O   1 
HETATM 4851 O O   . HOH   E 3 .   ? 4.75939   17.91030  -18.02874 1.000 41.79358 ?  522 HOH   A O   1 
HETATM 4852 O O   . HOH   E 3 .   ? -26.60359 -23.52357 -16.05054 1.000 43.64822 ?  523 HOH   A O   1 
HETATM 4853 O O   . HOH   E 3 .   ? -11.54091 7.65597   -6.20294  1.000 40.36040 ?  524 HOH   A O   1 
HETATM 4854 O O   . HOH   E 3 .   ? -9.64109  -12.49976 -22.93447 1.000 31.87040 ?  525 HOH   A O   1 
HETATM 4855 O O   . HOH   E 3 .   ? 0.22494   -10.13544 -17.55732 1.000 43.11539 ?  526 HOH   A O   1 
HETATM 4856 O O   . HOH   E 3 .   ? -1.82824  13.22188  -25.96995 1.000 32.40078 ?  527 HOH   A O   1 
HETATM 4857 O O   . HOH   E 3 .   ? 5.11502   12.70408  -23.28254 1.000 37.72057 ?  528 HOH   A O   1 
HETATM 4858 O O   . HOH   E 3 .   ? -21.20186 -40.90064 -15.58987 1.000 40.14492 ?  529 HOH   A O   1 
HETATM 4859 O O   . HOH   E 3 .   ? -2.58541  -43.97547 -19.32820 1.000 36.54681 ?  530 HOH   A O   1 
HETATM 4860 O O   . HOH   E 3 .   ? -1.88661  -13.62978 -25.44815 1.000 35.95611 ?  531 HOH   A O   1 
HETATM 4861 O O   . HOH   E 3 .   ? -19.97577 19.74585  -17.50184 1.000 45.93515 ?  532 HOH   A O   1 
HETATM 4862 O O   . HOH   E 3 .   ? -23.83369 -25.10274 -10.38928 1.000 40.53384 ?  533 HOH   A O   1 
HETATM 4863 O O   . HOH   E 3 .   ? 3.00250   17.04919  -23.65855 1.000 44.97986 ?  534 HOH   A O   1 
HETATM 4864 O O   . HOH   E 3 .   ? -10.38157 19.55630  -10.78535 1.000 45.07188 ?  535 HOH   A O   1 
HETATM 4865 O O   . HOH   E 3 .   ? -14.08446 22.56551  -17.97708 1.000 50.77989 ?  536 HOH   A O   1 
HETATM 4866 O O   . HOH   E 3 .   ? -13.23954 -23.98038 -33.24042 1.000 39.03129 ?  537 HOH   A O   1 
HETATM 4867 O O   . HOH   E 3 .   ? -11.42060 -42.10052 -18.56755 1.000 35.22837 ?  538 HOH   A O   1 
HETATM 4868 O O   . HOH   E 3 .   ? -9.23742  -35.69671 0.00880   1.000 41.96013 ?  539 HOH   A O   1 
HETATM 4869 O O   . HOH   E 3 .   ? -26.26826 -24.37027 -11.69746 1.000 48.00518 ?  540 HOH   A O   1 
HETATM 4870 O O   . HOH   E 3 .   ? -21.86252 -15.86013 -33.03100 1.000 50.63921 ?  541 HOH   A O   1 
HETATM 4871 O O   . HOH   E 3 .   ? 2.62959   -12.56418 -13.82999 1.000 41.59370 ?  542 HOH   A O   1 
HETATM 4872 O O   . HOH   E 3 .   ? -2.66477  2.12350   -16.20433 1.000 27.85843 ?  543 HOH   A O   1 
HETATM 4873 O O   . HOH   E 3 .   ? -6.31894  -29.10703 1.76966   1.000 47.63576 ?  544 HOH   A O   1 
HETATM 4874 O O   . HOH   E 3 .   ? -9.80738  -6.01019  -21.45720 1.000 42.95111 ?  545 HOH   A O   1 
HETATM 4875 O O   . HOH   E 3 .   ? -8.05307  -11.39476 -27.50184 1.000 48.43463 ?  546 HOH   A O   1 
HETATM 4876 O O   . HOH   E 3 .   ? -9.47988  -1.63116  -24.03720 1.000 39.20639 ?  547 HOH   A O   1 
HETATM 4877 O O   . HOH   E 3 .   ? -13.28076 0.77238   -9.20150  1.000 34.42593 ?  548 HOH   A O   1 
HETATM 4878 O O   . HOH   E 3 .   ? -25.07355 -23.07018 -24.04445 1.000 41.65015 ?  549 HOH   A O   1 
HETATM 4879 O O   . HOH   E 3 .   ? -6.17628  -32.32512 5.05956   1.000 53.41635 ?  550 HOH   A O   1 
HETATM 4880 O O   . HOH   E 3 .   ? 5.52788   -30.07299 -8.44139  1.000 39.05661 ?  551 HOH   A O   1 
HETATM 4881 O O   . HOH   E 3 .   ? -22.20149 -42.08128 -19.46387 1.000 41.29070 ?  552 HOH   A O   1 
HETATM 4882 O O   . HOH   E 3 .   ? -1.07791  -39.63438 -22.99082 1.000 40.06711 ?  553 HOH   A O   1 
HETATM 4883 O O   . HOH   E 3 .   ? -24.91041 8.27573   -17.97985 1.000 49.89405 ?  554 HOH   A O   1 
HETATM 4884 O O   . HOH   E 3 .   ? 1.05527   -3.21644  -7.82430  1.000 44.37911 ?  555 HOH   A O   1 
HETATM 4885 O O   . HOH   E 3 .   ? -20.569   6.184     -5.728    1.000 49.24873 ?  556 HOH   A O   1 
HETATM 4886 O O   . HOH   E 3 .   ? -2.32077  -27.68239 -26.07980 1.000 42.09347 ?  557 HOH   A O   1 
HETATM 4887 O O   . HOH   E 3 .   ? -22.018   -15.108   -27.917   1.000 40.64900 ?  558 HOH   A O   1 
HETATM 4888 O O   . HOH   E 3 .   ? -17.45730 -29.89263 -5.94135  1.000 44.24518 ?  559 HOH   A O   1 
HETATM 4889 O O   . HOH   E 3 .   ? -22.92008 -18.87228 -6.90915  1.000 45.62329 ?  560 HOH   A O   1 
HETATM 4890 O O   . HOH   E 3 .   ? 2.17592   -34.80352 -0.93282  1.000 53.53518 ?  561 HOH   A O   1 
HETATM 4891 O O   . HOH   E 3 .   ? -13.16863 -31.59832 -4.19490  1.000 34.77459 ?  562 HOH   A O   1 
HETATM 4892 O O   . HOH   E 3 .   ? -22.22744 -29.44720 -23.95123 1.000 47.45334 ?  563 HOH   A O   1 
HETATM 4893 O O   . HOH   E 3 .   ? -4.89257  -2.48256  -19.61319 1.000 41.16120 ?  564 HOH   A O   1 
HETATM 4894 O O   . HOH   E 3 .   ? -6.52794  -9.55276  -24.80162 1.000 46.59297 ?  565 HOH   A O   1 
HETATM 4895 O O   . HOH   E 3 .   ? 3.26813   -26.13222 -6.42193  1.000 42.55935 ?  566 HOH   A O   1 
HETATM 4896 O O   . HOH   E 3 .   ? -21.131   8.252     -4.520    1.000 51.06529 ?  567 HOH   A O   1 
HETATM 4897 O O   . HOH   E 3 .   ? -23.16331 -23.14271 -27.22755 1.000 42.37181 ?  568 HOH   A O   1 
HETATM 4898 O O   . HOH   E 3 .   ? -19.10350 -27.96731 -4.88781  1.000 47.10979 ?  569 HOH   A O   1 
HETATM 4899 O O   . HOH   E 3 .   ? -24.15806 -27.71667 -9.04605  1.000 46.43818 ?  570 HOH   A O   1 
HETATM 4900 O O   . HOH   E 3 .   ? -21.28351 -29.72759 -21.94360 1.000 48.24518 ?  571 HOH   A O   1 
HETATM 4901 O O   . HOH   E 3 .   ? -2.90028  -2.64870  -21.93088 1.000 44.81518 ?  572 HOH   A O   1 
HETATM 4902 O O   . HOH   E 3 .   ? 1.20138   -15.01888 3.95088   1.000 53.07321 ?  573 HOH   A O   1 
HETATM 4903 O O   . HOH   E 3 .   ? -2.27243  -18.04931 -22.92663 1.000 40.76300 ?  574 HOH   A O   1 
HETATM 4904 O O   . HOH   E 3 .   ? -18.66510 21.97373  -16.95061 1.000 45.84936 ?  575 HOH   A O   1 
HETATM 4905 O O   . HOH   E 3 .   ? 2.70822   -38.89378 -1.84515  1.000 53.78028 ?  576 HOH   A O   1 
HETATM 4906 O O   . HOH   E 3 .   ? -25.229   -20.584   -26.624   1.000 49.40518 ?  577 HOH   A O   1 
HETATM 4907 O O   . HOH   E 3 .   ? -2.49759  -24.88185 -25.27187 1.000 44.54873 ?  578 HOH   A O   1 
HETATM 4908 O O   . HOH   E 3 .   ? 4.87190   -24.64325 -8.21657  1.000 40.45258 ?  579 HOH   A O   1 
HETATM 4909 O O   . HOH   E 3 .   ? 0.75149   16.92604  -25.72389 1.000 53.65518 ?  580 HOH   A O   1 
HETATM 4910 O O   . HOH   E 3 .   ? 3.16567   -14.63716 2.85203   1.000 53.67576 ?  581 HOH   A O   1 
HETATM 4911 O O   . HOH   E 3 .   ? -8.74493  -10.74021 -24.78666 1.000 42.80568 ?  582 HOH   A O   1 
HETATM 4912 O O   . HOH   E 3 .   ? 1.95820   -36.97517 -17.97476 1.000 43.92172 ?  583 HOH   A O   1 
HETATM 4913 O O   . HOH   E 3 .   ? -2.22022  -0.47934  -15.39041 1.000 36.27749 ?  584 HOH   A O   1 
HETATM 4914 O O   . HOH   E 3 .   ? 4.10845   -37.76756 -3.92261  1.000 49.53320 ?  585 HOH   A O   1 
HETATM 4915 O O   . HOH   E 3 .   ? -8.10255  -2.85998  -21.99460 1.000 38.57182 ?  586 HOH   A O   1 
HETATM 4916 O O   . HOH   E 3 .   ? -10.50141 -16.43435 -33.63392 1.000 52.63707 ?  587 HOH   A O   1 
HETATM 4917 O O   . HOH   E 3 .   ? -23.33386 -29.41790 -20.80696 1.000 57.10411 ?  588 HOH   A O   1 
HETATM 4918 O O   . HOH   E 3 .   ? 4.52623   -11.43185 -12.35300 1.000 47.00691 ?  589 HOH   A O   1 
HETATM 4919 O O   . HOH   E 3 .   ? -9.32141  -1.79357  -26.94472 1.000 54.63388 ?  590 HOH   A O   1 
HETATM 4920 O O   . HOH   E 3 .   ? 3.22202   -8.85014  -7.86505  1.000 46.97802 ?  591 HOH   A O   1 
HETATM 4921 O O   . HOH   E 3 .   ? 2.00581   -1.86155  -17.08404 1.000 43.73805 ?  592 HOH   A O   1 
HETATM 4922 O O   . HOH   E 3 .   ? 5.19200   -10.42434 -10.42355 1.000 48.08562 ?  593 HOH   A O   1 
HETATM 4923 O O   . HOH   E 3 .   ? 6.05010   -21.20465 -10.19150 1.000 43.43745 ?  594 HOH   A O   1 
HETATM 4924 O O   . HOH   E 3 .   ? -2.31804  -12.20095 3.82593   1.000 52.64097 ?  595 HOH   A O   1 
HETATM 4925 O O   . HOH   E 3 .   ? -0.71657  15.50347  -26.85853 1.000 43.73959 ?  596 HOH   A O   1 
HETATM 4926 O O   . HOH   E 3 .   ? 4.50835   -34.20990 -16.16267 1.000 43.75981 ?  597 HOH   A O   1 
HETATM 4927 O O   . HOH   E 3 .   ? 2.31399   10.21281  -24.70980 1.000 45.43160 ?  598 HOH   A O   1 
HETATM 4928 O O   . HOH   F 3 .   ? 17.01814  -14.41698 11.73227  1.000 47.72305 ?  401 HOH   B O   1 
HETATM 4929 O O   . HOH   F 3 .   ? 28.939    -16.512   -10.154   1.000 43.52987 ?  402 HOH   B O   1 
HETATM 4930 O O   . HOH   F 3 .   ? 26.90306  -4.43523  -10.05399 1.000 36.29436 ?  403 HOH   B O   1 
HETATM 4931 O O   . HOH   F 3 .   ? 29.84219  -3.29812  14.40831  1.000 42.42615 ?  404 HOH   B O   1 
HETATM 4932 O O   . HOH   F 3 .   ? 28.02861  -9.03485  17.37472  1.000 40.03919 ?  405 HOH   B O   1 
HETATM 4933 O O   . HOH   F 3 .   ? 17.95236  -19.88770 -13.12478 1.000 42.20720 ?  406 HOH   B O   1 
HETATM 4934 O O   . HOH   F 3 .   ? 39.32864  4.51081   10.68496  1.000 51.75384 ?  407 HOH   B O   1 
HETATM 4935 O O   . HOH   F 3 .   ? 21.56352  11.84612  11.25265  1.000 52.54518 ?  408 HOH   B O   1 
HETATM 4936 O O   . HOH   F 3 .   ? 34.06524  7.24082   9.69931   1.000 55.12970 ?  409 HOH   B O   1 
HETATM 4937 O O   . HOH   F 3 .   ? 5.64634   -9.52968  -16.73971 1.000 34.53387 ?  410 HOH   B O   1 
HETATM 4938 O O   . HOH   F 3 .   ? 25.65915  5.29393   0.61828   1.000 40.96707 ?  411 HOH   B O   1 
HETATM 4939 O O   . HOH   F 3 .   ? -0.82195  -4.92123  -34.77345 1.000 43.65483 ?  412 HOH   B O   1 
HETATM 4940 O O   . HOH   F 3 .   ? 9.54819   13.57608  -21.40114 1.000 37.36646 ?  413 HOH   B O   1 
HETATM 4941 O O   . HOH   F 3 .   ? 11.38325  -8.44700  13.34376  1.000 47.21866 ?  414 HOH   B O   1 
HETATM 4942 O O   . HOH   F 3 .   ? 23.01412  -4.27277  -32.92707 1.000 32.45255 ?  415 HOH   B O   1 
HETATM 4943 O O   . HOH   F 3 .   ? 36.82245  -17.25172 2.67009   1.000 53.88946 ?  416 HOH   B O   1 
HETATM 4944 O O   . HOH   F 3 .   ? 6.71181   3.23039   -40.82619 1.000 52.54138 ?  417 HOH   B O   1 
HETATM 4945 O O   . HOH   F 3 .   ? 22.86116  -12.77112 -9.67973  1.000 30.25979 ?  418 HOH   B O   1 
HETATM 4946 O O   . HOH   F 3 .   ? 26.33180  -9.72334  -7.76802  1.000 36.19805 ?  419 HOH   B O   1 
HETATM 4947 O O   . HOH   F 3 .   ? 7.17289   -14.00550 -23.84958 1.000 36.36326 ?  420 HOH   B O   1 
HETATM 4948 O O   . HOH   F 3 .   ? 14.39337  -4.79273  -43.70224 1.000 49.69034 ?  421 HOH   B O   1 
HETATM 4949 O O   . HOH   F 3 .   ? 21.04867  6.46699   -0.92203  1.000 38.24824 ?  422 HOH   B O   1 
HETATM 4950 O O   . HOH   F 3 .   ? 28.39627  -2.91284  16.08437  1.000 43.05765 ?  423 HOH   B O   1 
HETATM 4951 O O   . HOH   F 3 .   ? 28.34634  -2.63452  -24.00690 1.000 32.14058 ?  424 HOH   B O   1 
HETATM 4952 O O   . HOH   F 3 .   ? -5.12863  1.96587   -36.81048 1.000 43.37867 ?  425 HOH   B O   1 
HETATM 4953 O O   . HOH   F 3 .   ? 39.95682  -1.10748  1.02242   1.000 42.29425 ?  426 HOH   B O   1 
HETATM 4954 O O   . HOH   F 3 .   ? 15.52200  -13.62706 -42.15123 1.000 42.38653 ?  427 HOH   B O   1 
HETATM 4955 O O   . HOH   F 3 .   ? 21.83386  -13.08871 -6.03920  1.000 40.34274 ?  428 HOH   B O   1 
HETATM 4956 O O   . HOH   F 3 .   ? 22.33424  -10.77070 -24.56745 1.000 27.39545 ?  429 HOH   B O   1 
HETATM 4957 O O   . HOH   F 3 .   ? 20.63450  -26.14548 -19.99766 1.000 43.40499 ?  430 HOH   B O   1 
HETATM 4958 O O   . HOH   F 3 .   ? 18.51137  1.34006   19.05790  1.000 38.37165 ?  431 HOH   B O   1 
HETATM 4959 O O   . HOH   F 3 .   ? 1.76693   -11.20610 -21.22670 1.000 39.38892 ?  432 HOH   B O   1 
HETATM 4960 O O   . HOH   F 3 .   ? 19.22888  -4.32626  19.49360  1.000 46.49433 ?  433 HOH   B O   1 
HETATM 4961 O O   . HOH   F 3 .   ? 23.63120  -22.01814 -25.66009 1.000 35.49845 ?  434 HOH   B O   1 
HETATM 4962 O O   . HOH   F 3 .   ? 11.85706  -8.31642  2.59633   1.000 37.30026 ?  435 HOH   B O   1 
HETATM 4963 O O   . HOH   F 3 .   ? 22.35654  -1.73159  -11.59767 1.000 29.10115 ?  436 HOH   B O   1 
HETATM 4964 O O   . HOH   F 3 .   ? 9.58833   -23.88687 -36.37288 1.000 50.22382 ?  437 HOH   B O   1 
HETATM 4965 O O   . HOH   F 3 .   ? 11.37280  -0.55705  -5.27259  1.000 40.34288 ?  438 HOH   B O   1 
HETATM 4966 O O   . HOH   F 3 .   ? 1.24207   -7.95800  -39.01178 1.000 44.07645 ?  439 HOH   B O   1 
HETATM 4967 O O   . HOH   F 3 .   ? 11.10547  -12.56095 -17.87996 1.000 30.27429 ?  440 HOH   B O   1 
HETATM 4968 O O   . HOH   F 3 .   ? 18.84250  -8.11386  -2.19951  1.000 35.13585 ?  441 HOH   B O   1 
HETATM 4969 O O   . HOH   F 3 .   ? 5.74733   0.80514   -20.89532 1.000 25.49852 ?  442 HOH   B O   1 
HETATM 4970 O O   . HOH   F 3 .   ? 3.32085   -11.86677 -43.34689 1.000 46.48019 ?  443 HOH   B O   1 
HETATM 4971 O O   . HOH   F 3 .   ? 13.78505  4.48713   2.08646   1.000 37.70801 ?  444 HOH   B O   1 
HETATM 4972 O O   . HOH   F 3 .   ? 26.04993  3.86284   -1.99069  1.000 46.06284 ?  445 HOH   B O   1 
HETATM 4973 O O   . HOH   F 3 .   ? 26.93807  -20.51360 -19.61258 1.000 29.62504 ?  446 HOH   B O   1 
HETATM 4974 O O   . HOH   F 3 .   ? 11.64471  -4.04045  9.49695   1.000 41.22558 ?  447 HOH   B O   1 
HETATM 4975 O O   . HOH   F 3 .   ? 10.77495  -1.53640  -27.67396 1.000 26.94772 ?  448 HOH   B O   1 
HETATM 4976 O O   . HOH   F 3 .   ? 13.82972  -0.59852  -16.52719 1.000 25.61759 ?  449 HOH   B O   1 
HETATM 4977 O O   . HOH   F 3 .   ? 21.97370  -0.83348  -34.43126 1.000 41.72864 ?  450 HOH   B O   1 
HETATM 4978 O O   . HOH   F 3 .   ? 19.56002  -9.10129  -39.39006 1.000 39.46695 ?  451 HOH   B O   1 
HETATM 4979 O O   . HOH   F 3 .   ? 38.07249  -10.35729 9.87040   1.000 40.86890 ?  452 HOH   B O   1 
HETATM 4980 O O   . HOH   F 3 .   ? 10.84449  -20.13072 -27.35864 1.000 39.58981 ?  453 HOH   B O   1 
HETATM 4981 O O   . HOH   F 3 .   ? 7.95021   7.61432   -18.59458 1.000 31.45394 ?  454 HOH   B O   1 
HETATM 4982 O O   . HOH   F 3 .   ? 11.42114  4.98935   -11.19643 1.000 29.57724 ?  455 HOH   B O   1 
HETATM 4983 O O   . HOH   F 3 .   ? 8.48976   6.54503   -41.33202 1.000 55.40494 ?  456 HOH   B O   1 
HETATM 4984 O O   . HOH   F 3 .   ? 11.97912  11.78616  -10.10566 1.000 45.31277 ?  457 HOH   B O   1 
HETATM 4985 O O   . HOH   F 3 .   ? 20.08648  -13.31297 11.17613  1.000 44.68008 ?  458 HOH   B O   1 
HETATM 4986 O O   . HOH   F 3 .   ? 23.24876  2.74220   16.75942  1.000 42.58432 ?  459 HOH   B O   1 
HETATM 4987 O O   . HOH   F 3 .   ? 26.47915  -4.91354  -1.95364  1.000 26.29912 ?  460 HOH   B O   1 
HETATM 4988 O O   . HOH   F 3 .   ? 5.41668   1.06652   -23.55670 1.000 26.66383 ?  461 HOH   B O   1 
HETATM 4989 O O   . HOH   F 3 .   ? 16.64852  10.46067  -16.69205 1.000 31.24409 ?  462 HOH   B O   1 
HETATM 4990 O O   . HOH   F 3 .   ? 14.42418  8.42316   -21.82920 1.000 30.34577 ?  463 HOH   B O   1 
HETATM 4991 O O   . HOH   F 3 .   ? 12.84534  -2.83562  1.84475   1.000 37.90446 ?  464 HOH   B O   1 
HETATM 4992 O O   . HOH   F 3 .   ? 9.66469   -6.41551  -9.98394  1.000 39.75738 ?  465 HOH   B O   1 
HETATM 4993 O O   . HOH   F 3 .   ? 9.26473   -19.48882 -18.53685 1.000 41.95885 ?  466 HOH   B O   1 
HETATM 4994 O O   . HOH   F 3 .   ? 35.03129  -6.47583  -7.97563  1.000 41.12636 ?  467 HOH   B O   1 
HETATM 4995 O O   . HOH   F 3 .   ? 6.98742   -18.09235 -27.51272 1.000 43.76760 ?  468 HOH   B O   1 
HETATM 4996 O O   . HOH   F 3 .   ? 13.254    8.314     9.039     1.000 31.83043 ?  469 HOH   B O   1 
HETATM 4997 O O   . HOH   F 3 .   ? 18.51699  8.27213   -12.97325 1.000 34.57431 ?  470 HOH   B O   1 
HETATM 4998 O O   . HOH   F 3 .   ? 25.83302  9.21110   4.12841   1.000 44.36237 ?  471 HOH   B O   1 
HETATM 4999 O O   . HOH   F 3 .   ? 10.20393  -6.67852  9.12492   1.000 45.18698 ?  472 HOH   B O   1 
HETATM 5000 O O   . HOH   F 3 .   ? 24.06634  -23.20593 -9.87581  1.000 48.72978 ?  473 HOH   B O   1 
HETATM 5001 O O   . HOH   F 3 .   ? 4.03962   -15.10659 -21.26656 1.000 36.13234 ?  474 HOH   B O   1 
HETATM 5002 O O   . HOH   F 3 .   ? 1.95133   -3.34203  -22.77980 1.000 38.37416 ?  475 HOH   B O   1 
HETATM 5003 O O   . HOH   F 3 .   ? 26.87195  0.30167   -5.55883  1.000 41.70423 ?  476 HOH   B O   1 
HETATM 5004 O O   . HOH   F 3 .   ? 12.15375  -0.30986  -38.83043 1.000 46.74828 ?  477 HOH   B O   1 
HETATM 5005 O O   . HOH   F 3 .   ? 8.72033   -14.36077 -12.23698 1.000 40.24834 ?  478 HOH   B O   1 
HETATM 5006 O O   . HOH   F 3 .   ? 5.55403   -1.82815  -19.83407 1.000 25.63098 ?  479 HOH   B O   1 
HETATM 5007 O O   . HOH   F 3 .   ? 15.76562  -8.12109  13.98315  1.000 41.67899 ?  480 HOH   B O   1 
HETATM 5008 O O   . HOH   F 3 .   ? 33.04783  -16.61335 -25.92032 1.000 28.47017 ?  481 HOH   B O   1 
HETATM 5009 O O   . HOH   F 3 .   ? 25.42080  3.29329   15.33143  1.000 36.81604 ?  482 HOH   B O   1 
HETATM 5010 O O   . HOH   F 3 .   ? 30.63331  -7.59964  -13.43537 1.000 32.00373 ?  483 HOH   B O   1 
HETATM 5011 O O   . HOH   F 3 .   ? 18.50685  5.77335   -11.49642 1.000 33.96088 ?  484 HOH   B O   1 
HETATM 5012 O O   . HOH   F 3 .   ? 3.67904   -3.24123  -20.88436 1.000 33.79850 ?  485 HOH   B O   1 
HETATM 5013 O O   . HOH   F 3 .   ? 28.97824  -10.95854 -8.05802  1.000 30.84830 ?  486 HOH   B O   1 
HETATM 5014 O O   . HOH   F 3 .   ? 34.82954  -6.41288  -4.64657  1.000 47.58198 ?  487 HOH   B O   1 
HETATM 5015 O O   . HOH   F 3 .   ? 25.97125  5.03120   -24.12405 1.000 47.22811 ?  488 HOH   B O   1 
HETATM 5016 O O   . HOH   F 3 .   ? 19.43324  -12.57903 -7.92436  1.000 41.25218 ?  489 HOH   B O   1 
HETATM 5017 O O   . HOH   F 3 .   ? 22.22461  -11.67402 14.27956  1.000 39.57893 ?  490 HOH   B O   1 
HETATM 5018 O O   . HOH   F 3 .   ? 7.96917   -2.01755  -12.26757 1.000 32.58862 ?  491 HOH   B O   1 
HETATM 5019 O O   . HOH   F 3 .   ? 12.60200  -6.52189  -3.31803  1.000 44.61024 ?  492 HOH   B O   1 
HETATM 5020 O O   . HOH   F 3 .   ? 38.67174  -8.60036  -2.58332  1.000 50.31353 ?  493 HOH   B O   1 
HETATM 5021 O O   . HOH   F 3 .   ? 35.24220  3.92228   -5.23215  1.000 39.42551 ?  494 HOH   B O   1 
HETATM 5022 O O   . HOH   F 3 .   ? 11.95414  14.50264  -24.83779 1.000 35.02293 ?  495 HOH   B O   1 
HETATM 5023 O O   . HOH   F 3 .   ? 9.84787   3.04115   11.28683  1.000 46.38803 ?  496 HOH   B O   1 
HETATM 5024 O O   . HOH   F 3 .   ? 14.94748  -4.88357  16.94757  1.000 35.05959 ?  497 HOH   B O   1 
HETATM 5025 O O   . HOH   F 3 .   ? 26.755    -22.562   -17.179   1.000 46.19941 ?  498 HOH   B O   1 
HETATM 5026 O O   . HOH   F 3 .   ? 10.01613  -9.43954  6.75937   1.000 39.88738 ?  499 HOH   B O   1 
HETATM 5027 O O   . HOH   F 3 .   ? 0.43823   -7.32795  -26.07195 1.000 37.57655 ?  500 HOH   B O   1 
HETATM 5028 O O   . HOH   F 3 .   ? 0.47459   -9.63923  -32.26134 1.000 34.86611 ?  501 HOH   B O   1 
HETATM 5029 O O   . HOH   F 3 .   ? 22.81662  -21.79352 -32.89096 1.000 48.25986 ?  502 HOH   B O   1 
HETATM 5030 O O   . HOH   F 3 .   ? 27.85830  -21.08149 -26.70828 1.000 42.14196 ?  503 HOH   B O   1 
HETATM 5031 O O   . HOH   F 3 .   ? 13.08986  0.52216   18.79353  1.000 40.04584 ?  504 HOH   B O   1 
HETATM 5032 O O   . HOH   F 3 .   ? 15.06500  -3.43714  -3.10157  1.000 42.69835 ?  505 HOH   B O   1 
HETATM 5033 O O   . HOH   F 3 .   ? 1.89516   -13.56330 -28.12609 1.000 49.25155 ?  506 HOH   B O   1 
HETATM 5034 O O   . HOH   F 3 .   ? 17.12744  -3.57507  2.06217   1.000 27.09997 ?  507 HOH   B O   1 
HETATM 5035 O O   . HOH   F 3 .   ? 20.83622  -9.21030  15.14414  1.000 34.76772 ?  508 HOH   B O   1 
HETATM 5036 O O   . HOH   F 3 .   ? 22.73157  9.46028   -20.93690 1.000 39.87391 ?  509 HOH   B O   1 
HETATM 5037 O O   . HOH   F 3 .   ? 34.611    -7.083    -11.073   1.000 44.02015 ?  510 HOH   B O   1 
HETATM 5038 O O   . HOH   F 3 .   ? 33.83642  -4.46261  -3.63766  1.000 42.34088 ?  511 HOH   B O   1 
HETATM 5039 O O   . HOH   F 3 .   ? 24.66166  3.23017   -16.13908 1.000 33.46615 ?  512 HOH   B O   1 
HETATM 5040 O O   . HOH   F 3 .   ? 12.81361  -2.89778  16.31263  1.000 36.43348 ?  513 HOH   B O   1 
HETATM 5041 O O   . HOH   F 3 .   ? 19.63680  0.50337   -35.93567 1.000 43.20628 ?  514 HOH   B O   1 
HETATM 5042 O O   . HOH   F 3 .   ? 7.91566   -4.68322  -11.03834 1.000 35.34560 ?  515 HOH   B O   1 
HETATM 5043 O O   . HOH   F 3 .   ? 16.86908  -14.15171 -13.44901 1.000 30.59244 ?  516 HOH   B O   1 
HETATM 5044 O O   . HOH   F 3 .   ? 24.41078  -14.34701 -34.15269 1.000 45.26154 ?  517 HOH   B O   1 
HETATM 5045 O O   . HOH   F 3 .   ? 13.38224  -25.19549 -20.87795 1.000 37.61555 ?  518 HOH   B O   1 
HETATM 5046 O O   . HOH   F 3 .   ? 12.26187  -13.86485 -43.05005 1.000 47.51915 ?  519 HOH   B O   1 
HETATM 5047 O O   . HOH   F 3 .   ? 3.40493   5.12480   -35.64147 1.000 44.08866 ?  520 HOH   B O   1 
HETATM 5048 O O   . HOH   F 3 .   ? 13.25532  -2.07361  -3.09594  1.000 47.49709 ?  521 HOH   B O   1 
HETATM 5049 O O   . HOH   F 3 .   ? 28.49361  5.71657   -0.17113  1.000 38.18944 ?  522 HOH   B O   1 
HETATM 5050 O O   . HOH   F 3 .   ? 11.33500  -0.80664  11.45860  1.000 38.67254 ?  523 HOH   B O   1 
HETATM 5051 O O   . HOH   F 3 .   ? 2.39490   -14.74283 -40.67895 1.000 45.20790 ?  524 HOH   B O   1 
HETATM 5052 O O   . HOH   F 3 .   ? 13.94948  6.83973   2.09604   1.000 40.88573 ?  525 HOH   B O   1 
HETATM 5053 O O   . HOH   F 3 .   ? 16.55159  9.72346   -14.09767 1.000 35.57149 ?  526 HOH   B O   1 
HETATM 5054 O O   . HOH   F 3 .   ? 14.26517  11.36910  -39.87096 1.000 46.35776 ?  527 HOH   B O   1 
HETATM 5055 O O   . HOH   F 3 .   ? 14.10901  -7.67022  -1.06594  1.000 46.59899 ?  528 HOH   B O   1 
HETATM 5056 O O   . HOH   F 3 .   ? 31.54038  -2.89986  -8.92311  1.000 50.83067 ?  529 HOH   B O   1 
HETATM 5057 O O   . HOH   F 3 .   ? 26.34451  4.91926   -27.93255 1.000 41.56751 ?  530 HOH   B O   1 
HETATM 5058 O O   . HOH   F 3 .   ? 28.98712  -13.66285 -6.51279  1.000 40.81673 ?  531 HOH   B O   1 
HETATM 5059 O O   . HOH   F 3 .   ? 16.78702  -11.98247 14.07638  1.000 43.94378 ?  532 HOH   B O   1 
HETATM 5060 O O   . HOH   F 3 .   ? 26.19378  -13.80472 15.39150  1.000 44.40183 ?  533 HOH   B O   1 
HETATM 5061 O O   . HOH   F 3 .   ? 5.11002   0.45496   -16.90458 1.000 39.07839 ?  534 HOH   B O   1 
HETATM 5062 O O   . HOH   F 3 .   ? 14.58563  8.37856   -33.20863 1.000 51.56389 ?  535 HOH   B O   1 
HETATM 5063 O O   . HOH   F 3 .   ? 5.19882   -1.84749  -17.40004 1.000 40.25509 ?  536 HOH   B O   1 
HETATM 5064 O O   . HOH   F 3 .   ? 25.40848  -12.45924 -35.69785 1.000 49.81965 ?  537 HOH   B O   1 
HETATM 5065 O O   . HOH   F 3 .   ? 16.03528  10.42567  -10.13443 1.000 47.31518 ?  538 HOH   B O   1 
HETATM 5066 O O   . HOH   F 3 .   ? 37.58736  -14.63942 8.08172   1.000 52.01004 ?  539 HOH   B O   1 
HETATM 5067 O O   . HOH   F 3 .   ? 16.31784  -6.44158  -1.90313  1.000 40.68583 ?  540 HOH   B O   1 
HETATM 5068 O O   . HOH   F 3 .   ? 27.352    -14.770   -10.014   1.000 43.32800 ?  541 HOH   B O   1 
HETATM 5069 O O   . HOH   F 3 .   ? 19.84395  -13.06732 -1.53570  1.000 32.30180 ?  542 HOH   B O   1 
HETATM 5070 O O   . HOH   F 3 .   ? 25.84178  -23.07044 -25.82116 1.000 43.12514 ?  543 HOH   B O   1 
HETATM 5071 O O   . HOH   F 3 .   ? 8.29685   -12.89402 -16.72972 1.000 41.49379 ?  544 HOH   B O   1 
HETATM 5072 O O   . HOH   F 3 .   ? 4.41923   -8.12176  -14.94125 1.000 41.03323 ?  545 HOH   B O   1 
HETATM 5073 O O   . HOH   F 3 .   ? 11.44757  -6.02653  1.21836   1.000 45.57848 ?  546 HOH   B O   1 
HETATM 5074 O O   . HOH   F 3 .   ? 7.10800   -14.00637 -14.38124 1.000 49.19846 ?  547 HOH   B O   1 
HETATM 5075 O O   . HOH   F 3 .   ? 32.331    -8.999    -14.507   1.000 36.63647 ?  548 HOH   B O   1 
HETATM 5076 O O   . HOH   F 3 .   ? 15.96659  -4.03415  -0.35617  1.000 37.18096 ?  549 HOH   B O   1 
HETATM 5077 O O   . HOH   F 3 .   ? 16.22716  -15.68817 -11.16900 1.000 42.09306 ?  550 HOH   B O   1 
HETATM 5078 O O   . HOH   F 3 .   ? 0.00517   -7.95379  -36.64672 1.000 42.50723 ?  551 HOH   B O   1 
HETATM 5079 O O   . HOH   F 3 .   ? 13.07572  -10.46728 1.27393   1.000 49.54448 ?  552 HOH   B O   1 
HETATM 5080 O O   . HOH   F 3 .   ? 35.84857  -13.36908 9.86625   1.000 48.97775 ?  553 HOH   B O   1 
HETATM 5081 O O   . HOH   F 3 .   ? 0.66772   10.98502  -26.38741 1.000 43.78868 ?  554 HOH   B O   1 
HETATM 5082 O O   . HOH   F 3 .   ? 14.41210  -7.05877  15.79413  1.000 38.75620 ?  555 HOH   B O   1 
HETATM 5083 O O   . HOH   F 3 .   ? 34.789    -9.785    -27.960   1.000 49.16873 ?  556 HOH   B O   1 
HETATM 5084 O O   . HOH   F 3 .   ? 4.20561   -5.92725  -14.78461 1.000 46.75325 ?  557 HOH   B O   1 
HETATM 5085 O O   . HOH   F 3 .   ? 16.30620  12.00773  -12.71195 1.000 45.73876 ?  558 HOH   B O   1 
HETATM 5086 O O   . HOH   F 3 .   ? 9.78796   4.56338   -9.07031  1.000 49.99518 ?  559 HOH   B O   1 
HETATM 5087 O O   . HOH   F 3 .   ? 16.50296  13.16179  -16.40419 1.000 40.68541 ?  560 HOH   B O   1 
HETATM 5088 O O   . HOH   F 3 .   ? 9.44272   10.89807  -8.30055  1.000 42.24794 ?  561 HOH   B O   1 
HETATM 5089 O O   . HOH   F 3 .   ? 11.62658  -6.17032  14.99165  1.000 48.89855 ?  562 HOH   B O   1 
HETATM 5090 O O   . HOH   F 3 .   ? 16.58441  -5.38486  19.25728  1.000 43.30591 ?  563 HOH   B O   1 
HETATM 5091 O O   . HOH   F 3 .   ? 4.17040   1.94364   -41.59693 1.000 44.21708 ?  564 HOH   B O   1 
HETATM 5092 O O   . HOH   F 3 .   ? 33.347    -4.804    -10.586   1.000 46.15239 ?  565 HOH   B O   1 
HETATM 5093 O O   . HOH   F 3 .   ? 18.33388  -10.76681 -1.09518  1.000 42.14869 ?  566 HOH   B O   1 
HETATM 5094 O O   . HOH   F 3 .   ? 9.98115   -2.70552  2.93036   1.000 50.30327 ?  567 HOH   B O   1 
HETATM 5095 O O   . HOH   F 3 .   ? 17.89889  -9.66462  14.96808  1.000 39.80057 ?  568 HOH   B O   1 
HETATM 5096 O O   . HOH   F 3 .   ? 21.05928  -9.09169  17.95621  1.000 47.87388 ?  569 HOH   B O   1 
HETATM 5097 O O   . HOH   G 3 .   ? -13.10717 -22.23173 -0.57344  1.000 45.16518 ?  101 HOH   C O   1 
HETATM 5098 O O   . HOH   G 3 .   ? -10.15241 -28.10569 -2.31750  1.000 43.34518 ?  102 HOH   C O   1 
HETATM 5099 O O   . HOH   G 3 .   ? -10.75131 -30.62430 -3.09803  1.000 44.15998 ?  103 HOH   C O   1 
HETATM 5100 O O   . HOH   H 3 .   ? 18.68359  7.18608   -28.88831 1.000 42.78054 ?  101 HOH   D O   1 
HETATM 5101 O O   . HOH   H 3 .   ? 13.20985  16.84116  -23.83354 1.000 48.58618 ?  102 HOH   D O   1 
# 
