data_9B9Z
# 
_entry.id   9B9Z 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.400 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B9Z         pdb_00009b9z 10.2210/pdb9b9z/pdb 
WWPDB D_1000282846 ?            ?                   
EMDB  EMD-44393    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
1 'Structure model' 1 0 2024-11-20 
2 'Structure model' 1 1 2025-01-01 
# 
_pdbx_audit_revision_details.ordinal             1 
_pdbx_audit_revision_details.revision_ordinal    1 
_pdbx_audit_revision_details.data_content_type   'Structure model' 
_pdbx_audit_revision_details.provider            repository 
_pdbx_audit_revision_details.type                'Initial release' 
_pdbx_audit_revision_details.description         ? 
_pdbx_audit_revision_details.details             ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 2 'Structure model' 'Data collection'     
2 2 'Structure model' 'Database references' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 2 'Structure model' citation        
2 2 'Structure model' citation_author 
3 2 'Structure model' em_admin        
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1  2 'Structure model' '_citation.country'                 
2  2 'Structure model' '_citation.journal_abbrev'          
3  2 'Structure model' '_citation.journal_id_CSD'          
4  2 'Structure model' '_citation.journal_id_ISSN'         
5  2 'Structure model' '_citation.journal_volume'          
6  2 'Structure model' '_citation.page_first'              
7  2 'Structure model' '_citation.page_last'               
8  2 'Structure model' '_citation.pdbx_database_id_DOI'    
9  2 'Structure model' '_citation.pdbx_database_id_PubMed' 
10 2 'Structure model' '_citation.title'                   
11 2 'Structure model' '_citation.year'                    
12 2 'Structure model' '_citation_author.identifier_ORCID' 
13 2 'Structure model' '_em_admin.last_update'             
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B9Z 
_pdbx_database_status.recvd_initial_deposition_date   2024-04-03 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
_pdbx_database_related.db_name        EMDB 
_pdbx_database_related.details        . 
_pdbx_database_related.db_id          EMD-44393 
_pdbx_database_related.content_type   'associated EM volume' 
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              dan.rosenbaum@utsouthwestern.edu 
_pdbx_contact_author.name_first         Daniel 
_pdbx_contact_author.name_last          Rosenbaum 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-7174-4993 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Kumari, P.'      1  0000-0003-1834-0962 
'Dvoracsko, S.'   2  ?                   
'Enos, M.D.'      3  ?                   
'Ramesh, K.'      4  ?                   
'Lim, D.'         5  ?                   
'Hassan, S.A.'    6  ?                   
'Kunos, G.'       7  ?                   
'Cinar, R.'       8  ?                   
'Iyer, M.R.'      9  ?                   
'Rosenbaum, D.M.' 10 0000-0002-7174-4993 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                10694 
_citation.page_last                 10694 
_citation.title                     'Structural mechanism of CB 1 R binding to peripheral and biased inverse agonists.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-54206-0 
_citation.pdbx_database_id_PubMed   39695122 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Kumari, P.'      1  ?                   
primary 'Dvoracsko, S.'   2  ?                   
primary 'Enos, M.D.'      3  0000-0003-3208-7043 
primary 'Ramesh, K.'      4  ?                   
primary 'Lim, D.'         5  ?                   
primary 'Hassan, S.A.'    6  0000-0003-3319-078X 
primary 'Kunos, G.'       7  0000-0003-1788-4976 
primary 'Cinar, R.'       8  0000-0002-8597-7253 
primary 'Iyer, M.R.'      9  0000-0002-0116-4619 
primary 'Rosenbaum, D.M.' 10 0000-0002-7174-4993 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer     man CNb36 14061.530 1 ? ? ? ? 
2 polymer     man 'Cannabinoid receptor 1,Glycogen synthase' 60728.086 1 ? ? ? ? 
3 non-polymer syn 
;(4S)-3-(4-chlorophenyl)-N'-[(1E)-ethanimidoyl]-4-phenyl-N-[4-(trifluoromethyl)benzene-1-sulfonyl]-4,5-dihydro-1H-pyrazole-1-carboximidamide
;
547.980   1 ? ? ? ? 
# 
_entity_name_com.entity_id   2 
_entity_name_com.name        CB-R,CB1,CANN6 
# 
loop_
_entity_poly.entity_id 
_entity_poly.type 
_entity_poly.nstd_linkage 
_entity_poly.nstd_monomer 
_entity_poly.pdbx_seq_one_letter_code 
_entity_poly.pdbx_seq_one_letter_code_can 
_entity_poly.pdbx_strand_id 
_entity_poly.pdbx_target_identifier 
1 'polypeptide(L)' no no 
;QVQLQESGGGLVQAGGSLRLSCAASGTIFGPDVMGWYRQAPGKERELVAGISNGANTYYADSVKGRFTISRDNAKNTVYL
QMNSLKPEDTAVYYCAAEVLDYTFAYLYHAYWGQGTQVTVSSHHHHHH
;
;QVQLQESGGGLVQAGGSLRLSCAASGTIFGPDVMGWYRQAPGKERELVAGISNGANTYYADSVKGRFTISRDNAKNTVYL
QMNSLKPEDTAVYYCAAEVLDYTFAYLYHAYWGQGTQVTVSSHHHHHH
;
N ? 
2 'polypeptide(L)' no no 
;DYKDDDDAMDQVNITEFYNKSLSSFENLYFQGGIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVIL
HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTAKVGSLFLAAIDRYISIHRPL
AYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAG
IDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEG
WARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAG
DPGELANAILKALELSRSDLSKFRENCKKRAMSFSDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKT
VFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCENLYFQGHHHHHHHHHH
;
;DYKDDDDAMDQVNITEFYNKSLSSFENLYFQGGIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVIL
HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTAKVGSLFLAAIDRYISIHRPL
AYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDKTYLMFWIGVVSVLLLFIVYAYMYILWKAG
IDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELEG
WARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKAG
DPGELANAILKALELSRSDLSKFRENCKKRAMSFSDQARMDIELAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKT
VFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCENLYFQGHHHHHHHHHH
;
R ? 
# 
_pdbx_entity_nonpoly.entity_id   3 
_pdbx_entity_nonpoly.name        
;(4S)-3-(4-chlorophenyl)-N'-[(1E)-ethanimidoyl]-4-phenyl-N-[4-(trifluoromethyl)benzene-1-sulfonyl]-4,5-dihydro-1H-pyrazole-1-carboximidamide
;
_pdbx_entity_nonpoly.comp_id     A1AKO 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1   GLN n 
1 2   VAL n 
1 3   GLN n 
1 4   LEU n 
1 5   GLN n 
1 6   GLU n 
1 7   SER n 
1 8   GLY n 
1 9   GLY n 
1 10  GLY n 
1 11  LEU n 
1 12  VAL n 
1 13  GLN n 
1 14  ALA n 
1 15  GLY n 
1 16  GLY n 
1 17  SER n 
1 18  LEU n 
1 19  ARG n 
1 20  LEU n 
1 21  SER n 
1 22  CYS n 
1 23  ALA n 
1 24  ALA n 
1 25  SER n 
1 26  GLY n 
1 27  THR n 
1 28  ILE n 
1 29  PHE n 
1 30  GLY n 
1 31  PRO n 
1 32  ASP n 
1 33  VAL n 
1 34  MET n 
1 35  GLY n 
1 36  TRP n 
1 37  TYR n 
1 38  ARG n 
1 39  GLN n 
1 40  ALA n 
1 41  PRO n 
1 42  GLY n 
1 43  LYS n 
1 44  GLU n 
1 45  ARG n 
1 46  GLU n 
1 47  LEU n 
1 48  VAL n 
1 49  ALA n 
1 50  GLY n 
1 51  ILE n 
1 52  SER n 
1 53  ASN n 
1 54  GLY n 
1 55  ALA n 
1 56  ASN n 
1 57  THR n 
1 58  TYR n 
1 59  TYR n 
1 60  ALA n 
1 61  ASP n 
1 62  SER n 
1 63  VAL n 
1 64  LYS n 
1 65  GLY n 
1 66  ARG n 
1 67  PHE n 
1 68  THR n 
1 69  ILE n 
1 70  SER n 
1 71  ARG n 
1 72  ASP n 
1 73  ASN n 
1 74  ALA n 
1 75  LYS n 
1 76  ASN n 
1 77  THR n 
1 78  VAL n 
1 79  TYR n 
1 80  LEU n 
1 81  GLN n 
1 82  MET n 
1 83  ASN n 
1 84  SER n 
1 85  LEU n 
1 86  LYS n 
1 87  PRO n 
1 88  GLU n 
1 89  ASP n 
1 90  THR n 
1 91  ALA n 
1 92  VAL n 
1 93  TYR n 
1 94  TYR n 
1 95  CYS n 
1 96  ALA n 
1 97  ALA n 
1 98  GLU n 
1 99  VAL n 
1 100 LEU n 
1 101 ASP n 
1 102 TYR n 
1 103 THR n 
1 104 PHE n 
1 105 ALA n 
1 106 TYR n 
1 107 LEU n 
1 108 TYR n 
1 109 HIS n 
1 110 ALA n 
1 111 TYR n 
1 112 TRP n 
1 113 GLY n 
1 114 GLN n 
1 115 GLY n 
1 116 THR n 
1 117 GLN n 
1 118 VAL n 
1 119 THR n 
1 120 VAL n 
1 121 SER n 
1 122 SER n 
1 123 HIS n 
1 124 HIS n 
1 125 HIS n 
1 126 HIS n 
1 127 HIS n 
1 128 HIS n 
2 1   ASP n 
2 2   TYR n 
2 3   LYS n 
2 4   ASP n 
2 5   ASP n 
2 6   ASP n 
2 7   ASP n 
2 8   ALA n 
2 9   MET n 
2 10  ASP n 
2 11  GLN n 
2 12  VAL n 
2 13  ASN n 
2 14  ILE n 
2 15  THR n 
2 16  GLU n 
2 17  PHE n 
2 18  TYR n 
2 19  ASN n 
2 20  LYS n 
2 21  SER n 
2 22  LEU n 
2 23  SER n 
2 24  SER n 
2 25  PHE n 
2 26  GLU n 
2 27  ASN n 
2 28  LEU n 
2 29  TYR n 
2 30  PHE n 
2 31  GLN n 
2 32  GLY n 
2 33  GLY n 
2 34  ILE n 
2 35  GLN n 
2 36  CYS n 
2 37  GLY n 
2 38  GLU n 
2 39  ASN n 
2 40  PHE n 
2 41  MET n 
2 42  ASP n 
2 43  ILE n 
2 44  GLU n 
2 45  CYS n 
2 46  PHE n 
2 47  MET n 
2 48  VAL n 
2 49  LEU n 
2 50  ASN n 
2 51  PRO n 
2 52  SER n 
2 53  GLN n 
2 54  GLN n 
2 55  LEU n 
2 56  ALA n 
2 57  ILE n 
2 58  ALA n 
2 59  VAL n 
2 60  LEU n 
2 61  SER n 
2 62  LEU n 
2 63  THR n 
2 64  LEU n 
2 65  GLY n 
2 66  THR n 
2 67  PHE n 
2 68  THR n 
2 69  VAL n 
2 70  LEU n 
2 71  GLU n 
2 72  ASN n 
2 73  LEU n 
2 74  LEU n 
2 75  VAL n 
2 76  LEU n 
2 77  CYS n 
2 78  VAL n 
2 79  ILE n 
2 80  LEU n 
2 81  HIS n 
2 82  SER n 
2 83  ARG n 
2 84  SER n 
2 85  LEU n 
2 86  ARG n 
2 87  CYS n 
2 88  ARG n 
2 89  PRO n 
2 90  SER n 
2 91  TYR n 
2 92  HIS n 
2 93  PHE n 
2 94  ILE n 
2 95  GLY n 
2 96  SER n 
2 97  LEU n 
2 98  ALA n 
2 99  VAL n 
2 100 ALA n 
2 101 ASP n 
2 102 LEU n 
2 103 LEU n 
2 104 GLY n 
2 105 SER n 
2 106 VAL n 
2 107 ILE n 
2 108 PHE n 
2 109 VAL n 
2 110 TYR n 
2 111 SER n 
2 112 PHE n 
2 113 ILE n 
2 114 ASP n 
2 115 PHE n 
2 116 HIS n 
2 117 VAL n 
2 118 PHE n 
2 119 HIS n 
2 120 ARG n 
2 121 LYS n 
2 122 ASP n 
2 123 SER n 
2 124 ARG n 
2 125 ASN n 
2 126 VAL n 
2 127 PHE n 
2 128 LEU n 
2 129 PHE n 
2 130 LYS n 
2 131 LEU n 
2 132 GLY n 
2 133 GLY n 
2 134 VAL n 
2 135 THR n 
2 136 ALA n 
2 137 SER n 
2 138 PHE n 
2 139 THR n 
2 140 ALA n 
2 141 LYS n 
2 142 VAL n 
2 143 GLY n 
2 144 SER n 
2 145 LEU n 
2 146 PHE n 
2 147 LEU n 
2 148 ALA n 
2 149 ALA n 
2 150 ILE n 
2 151 ASP n 
2 152 ARG n 
2 153 TYR n 
2 154 ILE n 
2 155 SER n 
2 156 ILE n 
2 157 HIS n 
2 158 ARG n 
2 159 PRO n 
2 160 LEU n 
2 161 ALA n 
2 162 TYR n 
2 163 LYS n 
2 164 ARG n 
2 165 ILE n 
2 166 VAL n 
2 167 THR n 
2 168 ARG n 
2 169 PRO n 
2 170 LYS n 
2 171 ALA n 
2 172 VAL n 
2 173 VAL n 
2 174 ALA n 
2 175 PHE n 
2 176 CYS n 
2 177 LEU n 
2 178 MET n 
2 179 TRP n 
2 180 THR n 
2 181 ILE n 
2 182 ALA n 
2 183 ILE n 
2 184 VAL n 
2 185 ILE n 
2 186 ALA n 
2 187 VAL n 
2 188 LEU n 
2 189 PRO n 
2 190 LEU n 
2 191 LEU n 
2 192 GLY n 
2 193 TRP n 
2 194 ASN n 
2 195 CYS n 
2 196 GLU n 
2 197 LYS n 
2 198 LEU n 
2 199 GLN n 
2 200 SER n 
2 201 VAL n 
2 202 CYS n 
2 203 SER n 
2 204 ASP n 
2 205 ILE n 
2 206 PHE n 
2 207 PRO n 
2 208 HIS n 
2 209 ILE n 
2 210 ASP n 
2 211 LYS n 
2 212 THR n 
2 213 TYR n 
2 214 LEU n 
2 215 MET n 
2 216 PHE n 
2 217 TRP n 
2 218 ILE n 
2 219 GLY n 
2 220 VAL n 
2 221 VAL n 
2 222 SER n 
2 223 VAL n 
2 224 LEU n 
2 225 LEU n 
2 226 LEU n 
2 227 PHE n 
2 228 ILE n 
2 229 VAL n 
2 230 TYR n 
2 231 ALA n 
2 232 TYR n 
2 233 MET n 
2 234 TYR n 
2 235 ILE n 
2 236 LEU n 
2 237 TRP n 
2 238 LYS n 
2 239 ALA n 
2 240 GLY n 
2 241 ILE n 
2 242 ASP n 
2 243 CYS n 
2 244 SER n 
2 245 PHE n 
2 246 TRP n 
2 247 ASN n 
2 248 GLU n 
2 249 SER n 
2 250 TYR n 
2 251 LEU n 
2 252 THR n 
2 253 GLY n 
2 254 SER n 
2 255 ARG n 
2 256 ASP n 
2 257 GLU n 
2 258 ARG n 
2 259 LYS n 
2 260 LYS n 
2 261 SER n 
2 262 LEU n 
2 263 LEU n 
2 264 SER n 
2 265 LYS n 
2 266 PHE n 
2 267 GLY n 
2 268 MET n 
2 269 ASP n 
2 270 GLU n 
2 271 GLY n 
2 272 VAL n 
2 273 THR n 
2 274 PHE n 
2 275 MET n 
2 276 PHE n 
2 277 ILE n 
2 278 GLY n 
2 279 ARG n 
2 280 PHE n 
2 281 ASP n 
2 282 ARG n 
2 283 GLY n 
2 284 GLN n 
2 285 LYS n 
2 286 GLY n 
2 287 VAL n 
2 288 ASP n 
2 289 VAL n 
2 290 LEU n 
2 291 LEU n 
2 292 LYS n 
2 293 ALA n 
2 294 ILE n 
2 295 GLU n 
2 296 ILE n 
2 297 LEU n 
2 298 SER n 
2 299 SER n 
2 300 LYS n 
2 301 LYS n 
2 302 GLU n 
2 303 PHE n 
2 304 GLN n 
2 305 GLU n 
2 306 MET n 
2 307 ARG n 
2 308 PHE n 
2 309 ILE n 
2 310 ILE n 
2 311 ILE n 
2 312 GLY n 
2 313 LYS n 
2 314 GLY n 
2 315 ASP n 
2 316 PRO n 
2 317 GLU n 
2 318 LEU n 
2 319 GLU n 
2 320 GLY n 
2 321 TRP n 
2 322 ALA n 
2 323 ARG n 
2 324 SER n 
2 325 LEU n 
2 326 GLU n 
2 327 GLU n 
2 328 LYS n 
2 329 HIS n 
2 330 GLY n 
2 331 ASN n 
2 332 VAL n 
2 333 LYS n 
2 334 VAL n 
2 335 ILE n 
2 336 THR n 
2 337 GLU n 
2 338 MET n 
2 339 LEU n 
2 340 SER n 
2 341 ARG n 
2 342 GLU n 
2 343 PHE n 
2 344 VAL n 
2 345 ARG n 
2 346 GLU n 
2 347 LEU n 
2 348 TYR n 
2 349 GLY n 
2 350 SER n 
2 351 VAL n 
2 352 ASP n 
2 353 PHE n 
2 354 VAL n 
2 355 ILE n 
2 356 ILE n 
2 357 PRO n 
2 358 SER n 
2 359 TYR n 
2 360 PHE n 
2 361 GLU n 
2 362 PRO n 
2 363 PHE n 
2 364 GLY n 
2 365 LEU n 
2 366 VAL n 
2 367 ALA n 
2 368 LEU n 
2 369 GLU n 
2 370 ALA n 
2 371 MET n 
2 372 CYS n 
2 373 LEU n 
2 374 GLY n 
2 375 ALA n 
2 376 ILE n 
2 377 PRO n 
2 378 ILE n 
2 379 ALA n 
2 380 SER n 
2 381 ALA n 
2 382 VAL n 
2 383 GLY n 
2 384 GLY n 
2 385 LEU n 
2 386 ARG n 
2 387 ASP n 
2 388 ILE n 
2 389 ILE n 
2 390 THR n 
2 391 ASN n 
2 392 GLU n 
2 393 THR n 
2 394 GLY n 
2 395 ILE n 
2 396 LEU n 
2 397 VAL n 
2 398 LYS n 
2 399 ALA n 
2 400 GLY n 
2 401 ASP n 
2 402 PRO n 
2 403 GLY n 
2 404 GLU n 
2 405 LEU n 
2 406 ALA n 
2 407 ASN n 
2 408 ALA n 
2 409 ILE n 
2 410 LEU n 
2 411 LYS n 
2 412 ALA n 
2 413 LEU n 
2 414 GLU n 
2 415 LEU n 
2 416 SER n 
2 417 ARG n 
2 418 SER n 
2 419 ASP n 
2 420 LEU n 
2 421 SER n 
2 422 LYS n 
2 423 PHE n 
2 424 ARG n 
2 425 GLU n 
2 426 ASN n 
2 427 CYS n 
2 428 LYS n 
2 429 LYS n 
2 430 ARG n 
2 431 ALA n 
2 432 MET n 
2 433 SER n 
2 434 PHE n 
2 435 SER n 
2 436 ASP n 
2 437 GLN n 
2 438 ALA n 
2 439 ARG n 
2 440 MET n 
2 441 ASP n 
2 442 ILE n 
2 443 GLU n 
2 444 LEU n 
2 445 ALA n 
2 446 LYS n 
2 447 THR n 
2 448 LEU n 
2 449 VAL n 
2 450 LEU n 
2 451 ILE n 
2 452 LEU n 
2 453 VAL n 
2 454 VAL n 
2 455 LEU n 
2 456 ILE n 
2 457 ILE n 
2 458 CYS n 
2 459 TRP n 
2 460 GLY n 
2 461 PRO n 
2 462 LEU n 
2 463 LEU n 
2 464 ALA n 
2 465 ILE n 
2 466 MET n 
2 467 VAL n 
2 468 TYR n 
2 469 ASP n 
2 470 VAL n 
2 471 PHE n 
2 472 GLY n 
2 473 LYS n 
2 474 MET n 
2 475 ASN n 
2 476 LYS n 
2 477 LEU n 
2 478 ILE n 
2 479 LYS n 
2 480 THR n 
2 481 VAL n 
2 482 PHE n 
2 483 ALA n 
2 484 PHE n 
2 485 CYS n 
2 486 SER n 
2 487 MET n 
2 488 LEU n 
2 489 CYS n 
2 490 LEU n 
2 491 LEU n 
2 492 ASN n 
2 493 SER n 
2 494 THR n 
2 495 VAL n 
2 496 ASN n 
2 497 PRO n 
2 498 ILE n 
2 499 ILE n 
2 500 TYR n 
2 501 ALA n 
2 502 LEU n 
2 503 ARG n 
2 504 SER n 
2 505 LYS n 
2 506 ASP n 
2 507 LEU n 
2 508 ARG n 
2 509 HIS n 
2 510 ALA n 
2 511 PHE n 
2 512 ARG n 
2 513 SER n 
2 514 MET n 
2 515 PHE n 
2 516 PRO n 
2 517 SER n 
2 518 CYS n 
2 519 GLU n 
2 520 ASN n 
2 521 LEU n 
2 522 TYR n 
2 523 PHE n 
2 524 GLN n 
2 525 GLY n 
2 526 HIS n 
2 527 HIS n 
2 528 HIS n 
2 529 HIS n 
2 530 HIS n 
2 531 HIS n 
2 532 HIS n 
2 533 HIS n 
2 534 HIS n 
2 535 HIS n 
# 
loop_
_entity_src_gen.entity_id 
_entity_src_gen.pdbx_src_id 
_entity_src_gen.pdbx_alt_source_flag 
_entity_src_gen.pdbx_seq_type 
_entity_src_gen.pdbx_beg_seq_num 
_entity_src_gen.pdbx_end_seq_num 
_entity_src_gen.gene_src_common_name 
_entity_src_gen.gene_src_genus 
_entity_src_gen.pdbx_gene_src_gene 
_entity_src_gen.gene_src_species 
_entity_src_gen.gene_src_strain 
_entity_src_gen.gene_src_tissue 
_entity_src_gen.gene_src_tissue_fraction 
_entity_src_gen.gene_src_details 
_entity_src_gen.pdbx_gene_src_fragment 
_entity_src_gen.pdbx_gene_src_scientific_name 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id 
_entity_src_gen.pdbx_gene_src_variant 
_entity_src_gen.pdbx_gene_src_cell_line 
_entity_src_gen.pdbx_gene_src_atcc 
_entity_src_gen.pdbx_gene_src_organ 
_entity_src_gen.pdbx_gene_src_organelle 
_entity_src_gen.pdbx_gene_src_cell 
_entity_src_gen.pdbx_gene_src_cellular_location 
_entity_src_gen.host_org_common_name 
_entity_src_gen.pdbx_host_org_scientific_name 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id 
_entity_src_gen.host_org_genus 
_entity_src_gen.pdbx_host_org_gene 
_entity_src_gen.pdbx_host_org_organ 
_entity_src_gen.host_org_species 
_entity_src_gen.pdbx_host_org_tissue 
_entity_src_gen.pdbx_host_org_tissue_fraction 
_entity_src_gen.pdbx_host_org_strain 
_entity_src_gen.pdbx_host_org_variant 
_entity_src_gen.pdbx_host_org_cell_line 
_entity_src_gen.pdbx_host_org_atcc 
_entity_src_gen.pdbx_host_org_culture_collection 
_entity_src_gen.pdbx_host_org_cell 
_entity_src_gen.pdbx_host_org_organelle 
_entity_src_gen.pdbx_host_org_cellular_location 
_entity_src_gen.pdbx_host_org_vector_type 
_entity_src_gen.pdbx_host_org_vector 
_entity_src_gen.host_org_details 
_entity_src_gen.expression_system_id 
_entity_src_gen.plasmid_name 
_entity_src_gen.plasmid_details 
_entity_src_gen.pdbx_description 
1 1 sample 'Biological sequence' 1   128 llama ? ?           ? ?             ? ? ? ? 'Lama glama'            9844   ? ? ? ? ? ? ? 
?               'Escherichia coli'      562  ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 1 sample 'Biological sequence' 1   239 human ? 'CNR1, CNR' ? ?             ? ? ? ? 'Homo sapiens'          9606   ? ? ? ? ? ? ? 
'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 2 sample 'Biological sequence' 240 435 ?     ? PAB2292     ? 'GE5 / Orsay' ? ? ? ? 'Pyrococcus abyssi GE5' 272844 ? ? ? ? ? ? ? 
'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
2 3 sample 'Biological sequence' 436 535 human ? 'CNR1, CNR' ? ?             ? ? ? ? 'Homo sapiens'          9606   ? ? ? ? ? ? ? 
'fall armyworm' 'Spodoptera frugiperda' 7108 ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
A1AKO non-polymer         . 
;(4S)-3-(4-chlorophenyl)-N'-[(1E)-ethanimidoyl]-4-phenyl-N-[4-(trifluoromethyl)benzene-1-sulfonyl]-4,5-dihydro-1H-pyrazole-1-carboximidamide
;
? 'C25 H21 Cl F3 N5 O2 S' 547.980 
ALA   'L-peptide linking' y ALANINE ? 'C3 H7 N O2'            89.093  
ARG   'L-peptide linking' y ARGININE ? 'C6 H15 N4 O2 1'        175.209 
ASN   'L-peptide linking' y ASPARAGINE ? 'C4 H8 N2 O3'           132.118 
ASP   'L-peptide linking' y 'ASPARTIC ACID' ? 'C4 H7 N O4'            133.103 
CYS   'L-peptide linking' y CYSTEINE ? 'C3 H7 N O2 S'          121.158 
GLN   'L-peptide linking' y GLUTAMINE ? 'C5 H10 N2 O3'          146.144 
GLU   'L-peptide linking' y 'GLUTAMIC ACID' ? 'C5 H9 N O4'            147.129 
GLY   'peptide linking'   y GLYCINE ? 'C2 H5 N O2'            75.067  
HIS   'L-peptide linking' y HISTIDINE ? 'C6 H10 N3 O2 1'        156.162 
ILE   'L-peptide linking' y ISOLEUCINE ? 'C6 H13 N O2'           131.173 
LEU   'L-peptide linking' y LEUCINE ? 'C6 H13 N O2'           131.173 
LYS   'L-peptide linking' y LYSINE ? 'C6 H15 N2 O2 1'        147.195 
MET   'L-peptide linking' y METHIONINE ? 'C5 H11 N O2 S'         149.211 
PHE   'L-peptide linking' y PHENYLALANINE ? 'C9 H11 N O2'           165.189 
PRO   'L-peptide linking' y PROLINE ? 'C5 H9 N O2'            115.130 
SER   'L-peptide linking' y SERINE ? 'C3 H7 N O3'            105.093 
THR   'L-peptide linking' y THREONINE ? 'C4 H9 N O3'            119.119 
TRP   'L-peptide linking' y TRYPTOPHAN ? 'C11 H12 N2 O2'         204.225 
TYR   'L-peptide linking' y TYROSINE ? 'C9 H11 N O3'           181.189 
VAL   'L-peptide linking' y VALINE ? 'C5 H11 N O2'           117.146 
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1   GLN 1   1    ?   ?   ?   N . n 
A 1 2   VAL 2   2    2   VAL VAL N . n 
A 1 3   GLN 3   3    3   GLN GLN N . n 
A 1 4   LEU 4   4    4   LEU LEU N . n 
A 1 5   GLN 5   5    5   GLN GLN N . n 
A 1 6   GLU 6   6    6   GLU GLU N . n 
A 1 7   SER 7   7    7   SER SER N . n 
A 1 8   GLY 8   8    8   GLY GLY N . n 
A 1 9   GLY 9   9    9   GLY GLY N . n 
A 1 10  GLY 10  10   10  GLY GLY N . n 
A 1 11  LEU 11  11   11  LEU LEU N . n 
A 1 12  VAL 12  12   12  VAL VAL N . n 
A 1 13  GLN 13  13   13  GLN GLN N . n 
A 1 14  ALA 14  14   14  ALA ALA N . n 
A 1 15  GLY 15  15   15  GLY GLY N . n 
A 1 16  GLY 16  16   16  GLY GLY N . n 
A 1 17  SER 17  17   17  SER SER N . n 
A 1 18  LEU 18  18   18  LEU LEU N . n 
A 1 19  ARG 19  19   19  ARG ARG N . n 
A 1 20  LEU 20  20   20  LEU LEU N . n 
A 1 21  SER 21  21   21  SER SER N . n 
A 1 22  CYS 22  22   22  CYS CYS N . n 
A 1 23  ALA 23  23   23  ALA ALA N . n 
A 1 24  ALA 24  24   24  ALA ALA N . n 
A 1 25  SER 25  25   25  SER SER N . n 
A 1 26  GLY 26  26   26  GLY GLY N . n 
A 1 27  THR 27  27   27  THR THR N . n 
A 1 28  ILE 28  28   28  ILE ILE N . n 
A 1 29  PHE 29  29   29  PHE PHE N . n 
A 1 30  GLY 30  30   30  GLY GLY N . n 
A 1 31  PRO 31  31   31  PRO PRO N . n 
A 1 32  ASP 32  32   32  ASP ASP N . n 
A 1 33  VAL 33  33   33  VAL VAL N . n 
A 1 34  MET 34  34   34  MET MET N . n 
A 1 35  GLY 35  35   35  GLY GLY N . n 
A 1 36  TRP 36  36   36  TRP TRP N . n 
A 1 37  TYR 37  37   37  TYR TYR N . n 
A 1 38  ARG 38  38   38  ARG ARG N . n 
A 1 39  GLN 39  39   39  GLN GLN N . n 
A 1 40  ALA 40  40   40  ALA ALA N . n 
A 1 41  PRO 41  41   41  PRO PRO N . n 
A 1 42  GLY 42  42   42  GLY GLY N . n 
A 1 43  LYS 43  43   43  LYS LYS N . n 
A 1 44  GLU 44  44   44  GLU GLU N . n 
A 1 45  ARG 45  45   45  ARG ARG N . n 
A 1 46  GLU 46  46   46  GLU GLU N . n 
A 1 47  LEU 47  47   47  LEU LEU N . n 
A 1 48  VAL 48  48   48  VAL VAL N . n 
A 1 49  ALA 49  49   49  ALA ALA N . n 
A 1 50  GLY 50  50   50  GLY GLY N . n 
A 1 51  ILE 51  51   51  ILE ILE N . n 
A 1 52  SER 52  52   52  SER SER N . n 
A 1 53  ASN 53  53   53  ASN ASN N . n 
A 1 54  GLY 54  54   54  GLY GLY N . n 
A 1 55  ALA 55  55   55  ALA ALA N . n 
A 1 56  ASN 56  56   56  ASN ASN N . n 
A 1 57  THR 57  57   57  THR THR N . n 
A 1 58  TYR 58  58   58  TYR TYR N . n 
A 1 59  TYR 59  59   59  TYR TYR N . n 
A 1 60  ALA 60  60   60  ALA ALA N . n 
A 1 61  ASP 61  61   61  ASP ASP N . n 
A 1 62  SER 62  62   62  SER SER N . n 
A 1 63  VAL 63  63   63  VAL VAL N . n 
A 1 64  LYS 64  64   64  LYS LYS N . n 
A 1 65  GLY 65  65   65  GLY GLY N . n 
A 1 66  ARG 66  66   66  ARG ARG N . n 
A 1 67  PHE 67  67   67  PHE PHE N . n 
A 1 68  THR 68  68   68  THR THR N . n 
A 1 69  ILE 69  69   69  ILE ILE N . n 
A 1 70  SER 70  70   70  SER SER N . n 
A 1 71  ARG 71  71   71  ARG ARG N . n 
A 1 72  ASP 72  72   72  ASP ASP N . n 
A 1 73  ASN 73  73   73  ASN ASN N . n 
A 1 74  ALA 74  74   74  ALA ALA N . n 
A 1 75  LYS 75  75   75  LYS LYS N . n 
A 1 76  ASN 76  76   76  ASN ASN N . n 
A 1 77  THR 77  77   77  THR THR N . n 
A 1 78  VAL 78  78   78  VAL VAL N . n 
A 1 79  TYR 79  79   79  TYR TYR N . n 
A 1 80  LEU 80  80   80  LEU LEU N . n 
A 1 81  GLN 81  81   81  GLN GLN N . n 
A 1 82  MET 82  82   82  MET MET N . n 
A 1 83  ASN 83  83   83  ASN ASN N . n 
A 1 84  SER 84  84   84  SER SER N . n 
A 1 85  LEU 85  85   85  LEU LEU N . n 
A 1 86  LYS 86  86   86  LYS LYS N . n 
A 1 87  PRO 87  87   87  PRO PRO N . n 
A 1 88  GLU 88  88   88  GLU GLU N . n 
A 1 89  ASP 89  89   89  ASP ASP N . n 
A 1 90  THR 90  90   90  THR THR N . n 
A 1 91  ALA 91  91   91  ALA ALA N . n 
A 1 92  VAL 92  92   92  VAL VAL N . n 
A 1 93  TYR 93  93   93  TYR TYR N . n 
A 1 94  TYR 94  94   94  TYR TYR N . n 
A 1 95  CYS 95  95   95  CYS CYS N . n 
A 1 96  ALA 96  96   96  ALA ALA N . n 
A 1 97  ALA 97  97   97  ALA ALA N . n 
A 1 98  GLU 98  98   98  GLU GLU N . n 
A 1 99  VAL 99  99   99  VAL VAL N . n 
A 1 100 LEU 100 100  100 LEU LEU N . n 
A 1 101 ASP 101 101  101 ASP ASP N . n 
A 1 102 TYR 102 102  102 TYR TYR N . n 
A 1 103 THR 103 103  103 THR THR N . n 
A 1 104 PHE 104 104  104 PHE PHE N . n 
A 1 105 ALA 105 105  105 ALA ALA N . n 
A 1 106 TYR 106 106  106 TYR TYR N . n 
A 1 107 LEU 107 107  107 LEU LEU N . n 
A 1 108 TYR 108 108  108 TYR TYR N . n 
A 1 109 HIS 109 109  109 HIS HIS N . n 
A 1 110 ALA 110 110  110 ALA ALA N . n 
A 1 111 TYR 111 111  111 TYR TYR N . n 
A 1 112 TRP 112 112  112 TRP TRP N . n 
A 1 113 GLY 113 113  113 GLY GLY N . n 
A 1 114 GLN 114 114  114 GLN GLN N . n 
A 1 115 GLY 115 115  115 GLY GLY N . n 
A 1 116 THR 116 116  116 THR THR N . n 
A 1 117 GLN 117 117  117 GLN GLN N . n 
A 1 118 VAL 118 118  118 VAL VAL N . n 
A 1 119 THR 119 119  119 THR THR N . n 
A 1 120 VAL 120 120  120 VAL VAL N . n 
A 1 121 SER 121 121  121 SER SER N . n 
A 1 122 SER 122 122  122 SER SER N . n 
A 1 123 HIS 123 123  123 HIS HIS N . n 
A 1 124 HIS 124 124  124 HIS HIS N . n 
A 1 125 HIS 125 125  ?   ?   ?   N . n 
A 1 126 HIS 126 126  ?   ?   ?   N . n 
A 1 127 HIS 127 127  ?   ?   ?   N . n 
A 1 128 HIS 128 128  ?   ?   ?   N . n 
B 2 1   ASP 1   63   ?   ?   ?   R . n 
B 2 2   TYR 2   64   ?   ?   ?   R . n 
B 2 3   LYS 3   65   ?   ?   ?   R . n 
B 2 4   ASP 4   66   ?   ?   ?   R . n 
B 2 5   ASP 5   67   ?   ?   ?   R . n 
B 2 6   ASP 6   68   ?   ?   ?   R . n 
B 2 7   ASP 7   69   ?   ?   ?   R . n 
B 2 8   ALA 8   70   ?   ?   ?   R . n 
B 2 9   MET 9   71   ?   ?   ?   R . n 
B 2 10  ASP 10  72   ?   ?   ?   R . n 
B 2 11  GLN 11  73   ?   ?   ?   R . n 
B 2 12  VAL 12  74   ?   ?   ?   R . n 
B 2 13  ASN 13  75   ?   ?   ?   R . n 
B 2 14  ILE 14  76   ?   ?   ?   R . n 
B 2 15  THR 15  77   ?   ?   ?   R . n 
B 2 16  GLU 16  78   ?   ?   ?   R . n 
B 2 17  PHE 17  79   ?   ?   ?   R . n 
B 2 18  TYR 18  80   ?   ?   ?   R . n 
B 2 19  ASN 19  81   ?   ?   ?   R . n 
B 2 20  LYS 20  82   ?   ?   ?   R . n 
B 2 21  SER 21  83   ?   ?   ?   R . n 
B 2 22  LEU 22  84   ?   ?   ?   R . n 
B 2 23  SER 23  85   ?   ?   ?   R . n 
B 2 24  SER 24  86   ?   ?   ?   R . n 
B 2 25  PHE 25  87   ?   ?   ?   R . n 
B 2 26  GLU 26  88   ?   ?   ?   R . n 
B 2 27  ASN 27  89   ?   ?   ?   R . n 
B 2 28  LEU 28  90   ?   ?   ?   R . n 
B 2 29  TYR 29  91   ?   ?   ?   R . n 
B 2 30  PHE 30  92   ?   ?   ?   R . n 
B 2 31  GLN 31  93   ?   ?   ?   R . n 
B 2 32  GLY 32  94   ?   ?   ?   R . n 
B 2 33  GLY 33  95   ?   ?   ?   R . n 
B 2 34  ILE 34  96   ?   ?   ?   R . n 
B 2 35  GLN 35  97   ?   ?   ?   R . n 
B 2 36  CYS 36  98   ?   ?   ?   R . n 
B 2 37  GLY 37  99   ?   ?   ?   R . n 
B 2 38  GLU 38  100  100 GLU GLU R . n 
B 2 39  ASN 39  101  101 ASN ASN R . n 
B 2 40  PHE 40  102  102 PHE PHE R . n 
B 2 41  MET 41  103  103 MET MET R . n 
B 2 42  ASP 42  104  104 ASP ASP R . n 
B 2 43  ILE 43  105  105 ILE ILE R . n 
B 2 44  GLU 44  106  106 GLU GLU R . n 
B 2 45  CYS 45  107  107 CYS CYS R . n 
B 2 46  PHE 46  108  108 PHE PHE R . n 
B 2 47  MET 47  109  109 MET MET R . n 
B 2 48  VAL 48  110  110 VAL VAL R . n 
B 2 49  LEU 49  111  111 LEU LEU R . n 
B 2 50  ASN 50  112  112 ASN ASN R . n 
B 2 51  PRO 51  113  113 PRO PRO R . n 
B 2 52  SER 52  114  114 SER SER R . n 
B 2 53  GLN 53  115  115 GLN GLN R . n 
B 2 54  GLN 54  116  116 GLN GLN R . n 
B 2 55  LEU 55  117  117 LEU LEU R . n 
B 2 56  ALA 56  118  118 ALA ALA R . n 
B 2 57  ILE 57  119  119 ILE ILE R . n 
B 2 58  ALA 58  120  120 ALA ALA R . n 
B 2 59  VAL 59  121  121 VAL VAL R . n 
B 2 60  LEU 60  122  122 LEU LEU R . n 
B 2 61  SER 61  123  123 SER SER R . n 
B 2 62  LEU 62  124  124 LEU LEU R . n 
B 2 63  THR 63  125  125 THR THR R . n 
B 2 64  LEU 64  126  126 LEU LEU R . n 
B 2 65  GLY 65  127  127 GLY GLY R . n 
B 2 66  THR 66  128  128 THR THR R . n 
B 2 67  PHE 67  129  129 PHE PHE R . n 
B 2 68  THR 68  130  130 THR THR R . n 
B 2 69  VAL 69  131  131 VAL VAL R . n 
B 2 70  LEU 70  132  132 LEU LEU R . n 
B 2 71  GLU 71  133  133 GLU GLU R . n 
B 2 72  ASN 72  134  134 ASN ASN R . n 
B 2 73  LEU 73  135  135 LEU LEU R . n 
B 2 74  LEU 74  136  136 LEU LEU R . n 
B 2 75  VAL 75  137  137 VAL VAL R . n 
B 2 76  LEU 76  138  138 LEU LEU R . n 
B 2 77  CYS 77  139  139 CYS CYS R . n 
B 2 78  VAL 78  140  140 VAL VAL R . n 
B 2 79  ILE 79  141  141 ILE ILE R . n 
B 2 80  LEU 80  142  142 LEU LEU R . n 
B 2 81  HIS 81  143  143 HIS HIS R . n 
B 2 82  SER 82  144  144 SER SER R . n 
B 2 83  ARG 83  145  145 ARG ARG R . n 
B 2 84  SER 84  146  146 SER SER R . n 
B 2 85  LEU 85  147  147 LEU LEU R . n 
B 2 86  ARG 86  148  148 ARG ARG R . n 
B 2 87  CYS 87  149  149 CYS CYS R . n 
B 2 88  ARG 88  150  150 ARG ARG R . n 
B 2 89  PRO 89  151  151 PRO PRO R . n 
B 2 90  SER 90  152  152 SER SER R . n 
B 2 91  TYR 91  153  153 TYR TYR R . n 
B 2 92  HIS 92  154  154 HIS HIS R . n 
B 2 93  PHE 93  155  155 PHE PHE R . n 
B 2 94  ILE 94  156  156 ILE ILE R . n 
B 2 95  GLY 95  157  157 GLY GLY R . n 
B 2 96  SER 96  158  158 SER SER R . n 
B 2 97  LEU 97  159  159 LEU LEU R . n 
B 2 98  ALA 98  160  160 ALA ALA R . n 
B 2 99  VAL 99  161  161 VAL VAL R . n 
B 2 100 ALA 100 162  162 ALA ALA R . n 
B 2 101 ASP 101 163  163 ASP ASP R . n 
B 2 102 LEU 102 164  164 LEU LEU R . n 
B 2 103 LEU 103 165  165 LEU LEU R . n 
B 2 104 GLY 104 166  166 GLY GLY R . n 
B 2 105 SER 105 167  167 SER SER R . n 
B 2 106 VAL 106 168  168 VAL VAL R . n 
B 2 107 ILE 107 169  169 ILE ILE R . n 
B 2 108 PHE 108 170  170 PHE PHE R . n 
B 2 109 VAL 109 171  171 VAL VAL R . n 
B 2 110 TYR 110 172  172 TYR TYR R . n 
B 2 111 SER 111 173  173 SER SER R . n 
B 2 112 PHE 112 174  174 PHE PHE R . n 
B 2 113 ILE 113 175  175 ILE ILE R . n 
B 2 114 ASP 114 176  176 ASP ASP R . n 
B 2 115 PHE 115 177  177 PHE PHE R . n 
B 2 116 HIS 116 178  178 HIS HIS R . n 
B 2 117 VAL 117 179  179 VAL VAL R . n 
B 2 118 PHE 118 180  180 PHE PHE R . n 
B 2 119 HIS 119 181  181 HIS HIS R . n 
B 2 120 ARG 120 182  182 ARG ARG R . n 
B 2 121 LYS 121 183  183 LYS LYS R . n 
B 2 122 ASP 122 184  184 ASP ASP R . n 
B 2 123 SER 123 185  185 SER SER R . n 
B 2 124 ARG 124 186  186 ARG ARG R . n 
B 2 125 ASN 125 187  187 ASN ASN R . n 
B 2 126 VAL 126 188  188 VAL VAL R . n 
B 2 127 PHE 127 189  189 PHE PHE R . n 
B 2 128 LEU 128 190  190 LEU LEU R . n 
B 2 129 PHE 129 191  191 PHE PHE R . n 
B 2 130 LYS 130 192  192 LYS LYS R . n 
B 2 131 LEU 131 193  193 LEU LEU R . n 
B 2 132 GLY 132 194  194 GLY GLY R . n 
B 2 133 GLY 133 195  195 GLY GLY R . n 
B 2 134 VAL 134 196  196 VAL VAL R . n 
B 2 135 THR 135 197  197 THR THR R . n 
B 2 136 ALA 136 198  198 ALA ALA R . n 
B 2 137 SER 137 199  199 SER SER R . n 
B 2 138 PHE 138 200  200 PHE PHE R . n 
B 2 139 THR 139 201  201 THR THR R . n 
B 2 140 ALA 140 202  202 ALA ALA R . n 
B 2 141 LYS 141 203  203 LYS LYS R . n 
B 2 142 VAL 142 204  204 VAL VAL R . n 
B 2 143 GLY 143 205  205 GLY GLY R . n 
B 2 144 SER 144 206  206 SER SER R . n 
B 2 145 LEU 145 207  207 LEU LEU R . n 
B 2 146 PHE 146 208  208 PHE PHE R . n 
B 2 147 LEU 147 209  209 LEU LEU R . n 
B 2 148 ALA 148 210  210 ALA ALA R . n 
B 2 149 ALA 149 211  211 ALA ALA R . n 
B 2 150 ILE 150 212  212 ILE ILE R . n 
B 2 151 ASP 151 213  213 ASP ASP R . n 
B 2 152 ARG 152 214  214 ARG ARG R . n 
B 2 153 TYR 153 215  215 TYR TYR R . n 
B 2 154 ILE 154 216  216 ILE ILE R . n 
B 2 155 SER 155 217  217 SER SER R . n 
B 2 156 ILE 156 218  218 ILE ILE R . n 
B 2 157 HIS 157 219  219 HIS HIS R . n 
B 2 158 ARG 158 220  220 ARG ARG R . n 
B 2 159 PRO 159 221  221 PRO PRO R . n 
B 2 160 LEU 160 222  222 LEU LEU R . n 
B 2 161 ALA 161 223  223 ALA ALA R . n 
B 2 162 TYR 162 224  224 TYR TYR R . n 
B 2 163 LYS 163 225  225 LYS LYS R . n 
B 2 164 ARG 164 226  226 ARG ARG R . n 
B 2 165 ILE 165 227  227 ILE ILE R . n 
B 2 166 VAL 166 228  228 VAL VAL R . n 
B 2 167 THR 167 229  229 THR THR R . n 
B 2 168 ARG 168 230  230 ARG ARG R . n 
B 2 169 PRO 169 231  231 PRO PRO R . n 
B 2 170 LYS 170 232  232 LYS LYS R . n 
B 2 171 ALA 171 233  233 ALA ALA R . n 
B 2 172 VAL 172 234  234 VAL VAL R . n 
B 2 173 VAL 173 235  235 VAL VAL R . n 
B 2 174 ALA 174 236  236 ALA ALA R . n 
B 2 175 PHE 175 237  237 PHE PHE R . n 
B 2 176 CYS 176 238  238 CYS CYS R . n 
B 2 177 LEU 177 239  239 LEU LEU R . n 
B 2 178 MET 178 240  240 MET MET R . n 
B 2 179 TRP 179 241  241 TRP TRP R . n 
B 2 180 THR 180 242  242 THR THR R . n 
B 2 181 ILE 181 243  243 ILE ILE R . n 
B 2 182 ALA 182 244  244 ALA ALA R . n 
B 2 183 ILE 183 245  245 ILE ILE R . n 
B 2 184 VAL 184 246  246 VAL VAL R . n 
B 2 185 ILE 185 247  247 ILE ILE R . n 
B 2 186 ALA 186 248  248 ALA ALA R . n 
B 2 187 VAL 187 249  249 VAL VAL R . n 
B 2 188 LEU 188 250  250 LEU LEU R . n 
B 2 189 PRO 189 251  251 PRO PRO R . n 
B 2 190 LEU 190 252  252 LEU LEU R . n 
B 2 191 LEU 191 253  253 LEU LEU R . n 
B 2 192 GLY 192 254  254 GLY GLY R . n 
B 2 193 TRP 193 255  255 TRP TRP R . n 
B 2 194 ASN 194 256  256 ASN ASN R . n 
B 2 195 CYS 195 257  257 CYS CYS R . n 
B 2 196 GLU 196 258  258 GLU GLU R . n 
B 2 197 LYS 197 259  259 LYS LYS R . n 
B 2 198 LEU 198 260  260 LEU LEU R . n 
B 2 199 GLN 199 261  261 GLN GLN R . n 
B 2 200 SER 200 262  262 SER SER R . n 
B 2 201 VAL 201 263  263 VAL VAL R . n 
B 2 202 CYS 202 264  264 CYS CYS R . n 
B 2 203 SER 203 265  265 SER SER R . n 
B 2 204 ASP 204 266  266 ASP ASP R . n 
B 2 205 ILE 205 267  267 ILE ILE R . n 
B 2 206 PHE 206 268  268 PHE PHE R . n 
B 2 207 PRO 207 269  269 PRO PRO R . n 
B 2 208 HIS 208 270  270 HIS HIS R . n 
B 2 209 ILE 209 271  271 ILE ILE R . n 
B 2 210 ASP 210 272  272 ASP ASP R . n 
B 2 211 LYS 211 273  273 LYS LYS R . n 
B 2 212 THR 212 274  274 THR THR R . n 
B 2 213 TYR 213 275  275 TYR TYR R . n 
B 2 214 LEU 214 276  276 LEU LEU R . n 
B 2 215 MET 215 277  277 MET MET R . n 
B 2 216 PHE 216 278  278 PHE PHE R . n 
B 2 217 TRP 217 279  279 TRP TRP R . n 
B 2 218 ILE 218 280  280 ILE ILE R . n 
B 2 219 GLY 219 281  281 GLY GLY R . n 
B 2 220 VAL 220 282  282 VAL VAL R . n 
B 2 221 VAL 221 283  283 VAL VAL R . n 
B 2 222 SER 222 284  284 SER SER R . n 
B 2 223 VAL 223 285  285 VAL VAL R . n 
B 2 224 LEU 224 286  286 LEU LEU R . n 
B 2 225 LEU 225 287  287 LEU LEU R . n 
B 2 226 LEU 226 288  288 LEU LEU R . n 
B 2 227 PHE 227 289  289 PHE PHE R . n 
B 2 228 ILE 228 290  290 ILE ILE R . n 
B 2 229 VAL 229 291  291 VAL VAL R . n 
B 2 230 TYR 230 292  292 TYR TYR R . n 
B 2 231 ALA 231 293  293 ALA ALA R . n 
B 2 232 TYR 232 294  294 TYR TYR R . n 
B 2 233 MET 233 295  295 MET MET R . n 
B 2 234 TYR 234 296  296 TYR TYR R . n 
B 2 235 ILE 235 297  297 ILE ILE R . n 
B 2 236 LEU 236 298  298 LEU LEU R . n 
B 2 237 TRP 237 299  299 TRP TRP R . n 
B 2 238 LYS 238 300  300 LYS LYS R . n 
B 2 239 ALA 239 301  301 ALA ALA R . n 
B 2 240 GLY 240 1001 302 GLY GLY R . n 
B 2 241 ILE 241 1002 303 ILE ILE R . n 
B 2 242 ASP 242 1003 304 ASP ASP R . n 
B 2 243 CYS 243 1004 305 CYS CYS R . n 
B 2 244 SER 244 1005 306 SER SER R . n 
B 2 245 PHE 245 1006 307 PHE PHE R . n 
B 2 246 TRP 246 1007 308 TRP TRP R . n 
B 2 247 ASN 247 1008 309 ASN ASN R . n 
B 2 248 GLU 248 1009 310 GLU GLU R . n 
B 2 249 SER 249 1010 311 SER SER R . n 
B 2 250 TYR 250 1011 312 TYR TYR R . n 
B 2 251 LEU 251 1012 313 LEU LEU R . n 
B 2 252 THR 252 1013 314 THR THR R . n 
B 2 253 GLY 253 1014 315 GLY GLY R . n 
B 2 254 SER 254 1015 316 SER SER R . n 
B 2 255 ARG 255 1016 317 ARG ARG R . n 
B 2 256 ASP 256 1017 318 ASP ASP R . n 
B 2 257 GLU 257 1018 319 GLU GLU R . n 
B 2 258 ARG 258 1019 320 ARG ARG R . n 
B 2 259 LYS 259 1020 321 LYS LYS R . n 
B 2 260 LYS 260 1021 322 LYS LYS R . n 
B 2 261 SER 261 1022 323 SER SER R . n 
B 2 262 LEU 262 1023 324 LEU LEU R . n 
B 2 263 LEU 263 1024 325 LEU LEU R . n 
B 2 264 SER 264 1025 326 SER SER R . n 
B 2 265 LYS 265 1026 327 LYS LYS R . n 
B 2 266 PHE 266 1027 328 PHE PHE R . n 
B 2 267 GLY 267 1028 329 GLY GLY R . n 
B 2 268 MET 268 1029 330 MET MET R . n 
B 2 269 ASP 269 1030 331 ASP ASP R . n 
B 2 270 GLU 270 1031 332 GLU GLU R . n 
B 2 271 GLY 271 1032 333 GLY GLY R . n 
B 2 272 VAL 272 1033 334 VAL VAL R . n 
B 2 273 THR 273 1034 335 THR THR R . n 
B 2 274 PHE 274 1035 336 PHE PHE R . n 
B 2 275 MET 275 1036 337 MET MET R . n 
B 2 276 PHE 276 1037 338 PHE PHE R . n 
B 2 277 ILE 277 1038 339 ILE ILE R . n 
B 2 278 GLY 278 1039 340 GLY GLY R . n 
B 2 279 ARG 279 1040 341 ARG ARG R . n 
B 2 280 PHE 280 1041 342 PHE PHE R . n 
B 2 281 ASP 281 1042 343 ASP ASP R . n 
B 2 282 ARG 282 1043 344 ARG ARG R . n 
B 2 283 GLY 283 1044 345 GLY GLY R . n 
B 2 284 GLN 284 1045 346 GLN GLN R . n 
B 2 285 LYS 285 1046 347 LYS LYS R . n 
B 2 286 GLY 286 1047 348 GLY GLY R . n 
B 2 287 VAL 287 1048 349 VAL VAL R . n 
B 2 288 ASP 288 1049 350 ASP ASP R . n 
B 2 289 VAL 289 1050 351 VAL VAL R . n 
B 2 290 LEU 290 1051 352 LEU LEU R . n 
B 2 291 LEU 291 1052 353 LEU LEU R . n 
B 2 292 LYS 292 1053 354 LYS LYS R . n 
B 2 293 ALA 293 1054 355 ALA ALA R . n 
B 2 294 ILE 294 1055 356 ILE ILE R . n 
B 2 295 GLU 295 1056 357 GLU GLU R . n 
B 2 296 ILE 296 1057 358 ILE ILE R . n 
B 2 297 LEU 297 1058 359 LEU LEU R . n 
B 2 298 SER 298 1059 360 SER SER R . n 
B 2 299 SER 299 1060 361 SER SER R . n 
B 2 300 LYS 300 1061 362 LYS LYS R . n 
B 2 301 LYS 301 1062 363 LYS LYS R . n 
B 2 302 GLU 302 1063 364 GLU GLU R . n 
B 2 303 PHE 303 1064 365 PHE PHE R . n 
B 2 304 GLN 304 1065 366 GLN GLN R . n 
B 2 305 GLU 305 1066 367 GLU GLU R . n 
B 2 306 MET 306 1067 368 MET MET R . n 
B 2 307 ARG 307 1068 369 ARG ARG R . n 
B 2 308 PHE 308 1069 370 PHE PHE R . n 
B 2 309 ILE 309 1070 371 ILE ILE R . n 
B 2 310 ILE 310 1071 372 ILE ILE R . n 
B 2 311 ILE 311 1072 373 ILE ILE R . n 
B 2 312 GLY 312 1073 374 GLY GLY R . n 
B 2 313 LYS 313 1074 375 LYS LYS R . n 
B 2 314 GLY 314 1075 376 GLY GLY R . n 
B 2 315 ASP 315 1076 377 ASP ASP R . n 
B 2 316 PRO 316 1077 378 PRO PRO R . n 
B 2 317 GLU 317 1078 379 GLU GLU R . n 
B 2 318 LEU 318 1079 380 LEU LEU R . n 
B 2 319 GLU 319 1080 381 GLU GLU R . n 
B 2 320 GLY 320 1081 382 GLY GLY R . n 
B 2 321 TRP 321 1082 383 TRP TRP R . n 
B 2 322 ALA 322 1083 384 ALA ALA R . n 
B 2 323 ARG 323 1084 385 ARG ARG R . n 
B 2 324 SER 324 1085 386 SER SER R . n 
B 2 325 LEU 325 1086 387 LEU LEU R . n 
B 2 326 GLU 326 1087 388 GLU GLU R . n 
B 2 327 GLU 327 1088 389 GLU GLU R . n 
B 2 328 LYS 328 1089 390 LYS LYS R . n 
B 2 329 HIS 329 1090 391 HIS HIS R . n 
B 2 330 GLY 330 1091 392 GLY GLY R . n 
B 2 331 ASN 331 1092 393 ASN ASN R . n 
B 2 332 VAL 332 1093 394 VAL VAL R . n 
B 2 333 LYS 333 1094 395 LYS LYS R . n 
B 2 334 VAL 334 1095 396 VAL VAL R . n 
B 2 335 ILE 335 1096 397 ILE ILE R . n 
B 2 336 THR 336 1097 398 THR THR R . n 
B 2 337 GLU 337 1098 399 GLU GLU R . n 
B 2 338 MET 338 1099 400 MET MET R . n 
B 2 339 LEU 339 1100 401 LEU LEU R . n 
B 2 340 SER 340 1101 402 SER SER R . n 
B 2 341 ARG 341 1102 403 ARG ARG R . n 
B 2 342 GLU 342 1103 404 GLU GLU R . n 
B 2 343 PHE 343 1104 405 PHE PHE R . n 
B 2 344 VAL 344 1105 406 VAL VAL R . n 
B 2 345 ARG 345 1106 407 ARG ARG R . n 
B 2 346 GLU 346 1107 408 GLU GLU R . n 
B 2 347 LEU 347 1108 409 LEU LEU R . n 
B 2 348 TYR 348 1109 410 TYR TYR R . n 
B 2 349 GLY 349 1110 411 GLY GLY R . n 
B 2 350 SER 350 1111 412 SER SER R . n 
B 2 351 VAL 351 1112 413 VAL VAL R . n 
B 2 352 ASP 352 1113 414 ASP ASP R . n 
B 2 353 PHE 353 1114 415 PHE PHE R . n 
B 2 354 VAL 354 1115 416 VAL VAL R . n 
B 2 355 ILE 355 1116 417 ILE ILE R . n 
B 2 356 ILE 356 1117 418 ILE ILE R . n 
B 2 357 PRO 357 1118 419 PRO PRO R . n 
B 2 358 SER 358 1119 420 SER SER R . n 
B 2 359 TYR 359 1120 421 TYR TYR R . n 
B 2 360 PHE 360 1121 422 PHE PHE R . n 
B 2 361 GLU 361 1122 423 GLU GLU R . n 
B 2 362 PRO 362 1123 424 PRO PRO R . n 
B 2 363 PHE 363 1124 425 PHE PHE R . n 
B 2 364 GLY 364 1125 426 GLY GLY R . n 
B 2 365 LEU 365 1126 427 LEU LEU R . n 
B 2 366 VAL 366 1127 428 VAL VAL R . n 
B 2 367 ALA 367 1128 429 ALA ALA R . n 
B 2 368 LEU 368 1129 430 LEU LEU R . n 
B 2 369 GLU 369 1130 431 GLU GLU R . n 
B 2 370 ALA 370 1131 432 ALA ALA R . n 
B 2 371 MET 371 1132 433 MET MET R . n 
B 2 372 CYS 372 1133 434 CYS CYS R . n 
B 2 373 LEU 373 1134 435 LEU LEU R . n 
B 2 374 GLY 374 1135 436 GLY GLY R . n 
B 2 375 ALA 375 1136 437 ALA ALA R . n 
B 2 376 ILE 376 1137 438 ILE ILE R . n 
B 2 377 PRO 377 1138 439 PRO PRO R . n 
B 2 378 ILE 378 1139 440 ILE ILE R . n 
B 2 379 ALA 379 1140 441 ALA ALA R . n 
B 2 380 SER 380 1141 442 SER SER R . n 
B 2 381 ALA 381 1142 443 ALA ALA R . n 
B 2 382 VAL 382 1143 444 VAL VAL R . n 
B 2 383 GLY 383 1144 445 GLY GLY R . n 
B 2 384 GLY 384 1145 446 GLY GLY R . n 
B 2 385 LEU 385 1146 447 LEU LEU R . n 
B 2 386 ARG 386 1147 448 ARG ARG R . n 
B 2 387 ASP 387 1148 449 ASP ASP R . n 
B 2 388 ILE 388 1149 450 ILE ILE R . n 
B 2 389 ILE 389 1150 451 ILE ILE R . n 
B 2 390 THR 390 1151 452 THR THR R . n 
B 2 391 ASN 391 1152 453 ASN ASN R . n 
B 2 392 GLU 392 1153 454 GLU GLU R . n 
B 2 393 THR 393 1154 455 THR THR R . n 
B 2 394 GLY 394 1155 456 GLY GLY R . n 
B 2 395 ILE 395 1156 457 ILE ILE R . n 
B 2 396 LEU 396 1157 458 LEU LEU R . n 
B 2 397 VAL 397 1158 459 VAL VAL R . n 
B 2 398 LYS 398 1159 460 LYS LYS R . n 
B 2 399 ALA 399 1160 461 ALA ALA R . n 
B 2 400 GLY 400 1161 462 GLY GLY R . n 
B 2 401 ASP 401 1162 463 ASP ASP R . n 
B 2 402 PRO 402 1163 464 PRO PRO R . n 
B 2 403 GLY 403 1164 465 GLY GLY R . n 
B 2 404 GLU 404 1165 466 GLU GLU R . n 
B 2 405 LEU 405 1166 467 LEU LEU R . n 
B 2 406 ALA 406 1167 468 ALA ALA R . n 
B 2 407 ASN 407 1168 469 ASN ASN R . n 
B 2 408 ALA 408 1169 470 ALA ALA R . n 
B 2 409 ILE 409 1170 471 ILE ILE R . n 
B 2 410 LEU 410 1171 472 LEU LEU R . n 
B 2 411 LYS 411 1172 473 LYS LYS R . n 
B 2 412 ALA 412 1173 474 ALA ALA R . n 
B 2 413 LEU 413 1174 475 LEU LEU R . n 
B 2 414 GLU 414 1175 476 GLU GLU R . n 
B 2 415 LEU 415 1176 477 LEU LEU R . n 
B 2 416 SER 416 1177 478 SER SER R . n 
B 2 417 ARG 417 1178 479 ARG ARG R . n 
B 2 418 SER 418 1179 480 SER SER R . n 
B 2 419 ASP 419 1180 481 ASP ASP R . n 
B 2 420 LEU 420 1181 482 LEU LEU R . n 
B 2 421 SER 421 1182 483 SER SER R . n 
B 2 422 LYS 422 1183 484 LYS LYS R . n 
B 2 423 PHE 423 1184 485 PHE PHE R . n 
B 2 424 ARG 424 1185 486 ARG ARG R . n 
B 2 425 GLU 425 1186 487 GLU GLU R . n 
B 2 426 ASN 426 1187 488 ASN ASN R . n 
B 2 427 CYS 427 1188 489 CYS CYS R . n 
B 2 428 LYS 428 1189 490 LYS LYS R . n 
B 2 429 LYS 429 1190 491 LYS LYS R . n 
B 2 430 ARG 430 1191 492 ARG ARG R . n 
B 2 431 ALA 431 1192 493 ALA ALA R . n 
B 2 432 MET 432 1193 494 MET MET R . n 
B 2 433 SER 433 1194 495 SER SER R . n 
B 2 434 PHE 434 1195 496 PHE PHE R . n 
B 2 435 SER 435 1196 497 SER SER R . n 
B 2 436 ASP 436 333  498 ASP ASP R . n 
B 2 437 GLN 437 334  499 GLN GLN R . n 
B 2 438 ALA 438 335  500 ALA ALA R . n 
B 2 439 ARG 439 336  501 ARG ARG R . n 
B 2 440 MET 440 337  502 MET MET R . n 
B 2 441 ASP 441 338  503 ASP ASP R . n 
B 2 442 ILE 442 339  504 ILE ILE R . n 
B 2 443 GLU 443 340  505 GLU GLU R . n 
B 2 444 LEU 444 341  506 LEU LEU R . n 
B 2 445 ALA 445 342  507 ALA ALA R . n 
B 2 446 LYS 446 343  508 LYS LYS R . n 
B 2 447 THR 447 344  509 THR THR R . n 
B 2 448 LEU 448 345  510 LEU LEU R . n 
B 2 449 VAL 449 346  511 VAL VAL R . n 
B 2 450 LEU 450 347  512 LEU LEU R . n 
B 2 451 ILE 451 348  513 ILE ILE R . n 
B 2 452 LEU 452 349  514 LEU LEU R . n 
B 2 453 VAL 453 350  515 VAL VAL R . n 
B 2 454 VAL 454 351  516 VAL VAL R . n 
B 2 455 LEU 455 352  517 LEU LEU R . n 
B 2 456 ILE 456 353  518 ILE ILE R . n 
B 2 457 ILE 457 354  519 ILE ILE R . n 
B 2 458 CYS 458 355  520 CYS CYS R . n 
B 2 459 TRP 459 356  521 TRP TRP R . n 
B 2 460 GLY 460 357  522 GLY GLY R . n 
B 2 461 PRO 461 358  523 PRO PRO R . n 
B 2 462 LEU 462 359  524 LEU LEU R . n 
B 2 463 LEU 463 360  525 LEU LEU R . n 
B 2 464 ALA 464 361  526 ALA ALA R . n 
B 2 465 ILE 465 362  527 ILE ILE R . n 
B 2 466 MET 466 363  528 MET MET R . n 
B 2 467 VAL 467 364  529 VAL VAL R . n 
B 2 468 TYR 468 365  530 TYR TYR R . n 
B 2 469 ASP 469 366  531 ASP ASP R . n 
B 2 470 VAL 470 367  532 VAL VAL R . n 
B 2 471 PHE 471 368  533 PHE PHE R . n 
B 2 472 GLY 472 369  534 GLY GLY R . n 
B 2 473 LYS 473 370  535 LYS LYS R . n 
B 2 474 MET 474 371  536 MET MET R . n 
B 2 475 ASN 475 372  537 ASN ASN R . n 
B 2 476 LYS 476 373  538 LYS LYS R . n 
B 2 477 LEU 477 374  539 LEU LEU R . n 
B 2 478 ILE 478 375  540 ILE ILE R . n 
B 2 479 LYS 479 376  541 LYS LYS R . n 
B 2 480 THR 480 377  542 THR THR R . n 
B 2 481 VAL 481 378  543 VAL VAL R . n 
B 2 482 PHE 482 379  544 PHE PHE R . n 
B 2 483 ALA 483 380  545 ALA ALA R . n 
B 2 484 PHE 484 381  546 PHE PHE R . n 
B 2 485 CYS 485 382  547 CYS CYS R . n 
B 2 486 SER 486 383  548 SER SER R . n 
B 2 487 MET 487 384  549 MET MET R . n 
B 2 488 LEU 488 385  550 LEU LEU R . n 
B 2 489 CYS 489 386  551 CYS CYS R . n 
B 2 490 LEU 490 387  552 LEU LEU R . n 
B 2 491 LEU 491 388  553 LEU LEU R . n 
B 2 492 ASN 492 389  554 ASN ASN R . n 
B 2 493 SER 493 390  555 SER SER R . n 
B 2 494 THR 494 391  556 THR THR R . n 
B 2 495 VAL 495 392  557 VAL VAL R . n 
B 2 496 ASN 496 393  558 ASN ASN R . n 
B 2 497 PRO 497 394  559 PRO PRO R . n 
B 2 498 ILE 498 395  560 ILE ILE R . n 
B 2 499 ILE 499 396  561 ILE ILE R . n 
B 2 500 TYR 500 397  562 TYR TYR R . n 
B 2 501 ALA 501 398  563 ALA ALA R . n 
B 2 502 LEU 502 399  564 LEU LEU R . n 
B 2 503 ARG 503 400  565 ARG ARG R . n 
B 2 504 SER 504 401  566 SER SER R . n 
B 2 505 LYS 505 402  567 LYS LYS R . n 
B 2 506 ASP 506 403  568 ASP ASP R . n 
B 2 507 LEU 507 404  569 LEU LEU R . n 
B 2 508 ARG 508 405  570 ARG ARG R . n 
B 2 509 HIS 509 406  571 HIS HIS R . n 
B 2 510 ALA 510 407  572 ALA ALA R . n 
B 2 511 PHE 511 408  573 PHE PHE R . n 
B 2 512 ARG 512 409  574 ARG ARG R . n 
B 2 513 SER 513 410  575 SER SER R . n 
B 2 514 MET 514 411  576 MET MET R . n 
B 2 515 PHE 515 412  577 PHE PHE R . n 
B 2 516 PRO 516 413  ?   ?   ?   R . n 
B 2 517 SER 517 414  ?   ?   ?   R . n 
B 2 518 CYS 518 415  ?   ?   ?   R . n 
B 2 519 GLU 519 416  ?   ?   ?   R . n 
B 2 520 ASN 520 417  ?   ?   ?   R . n 
B 2 521 LEU 521 418  ?   ?   ?   R . n 
B 2 522 TYR 522 419  ?   ?   ?   R . n 
B 2 523 PHE 523 420  ?   ?   ?   R . n 
B 2 524 GLN 524 421  ?   ?   ?   R . n 
B 2 525 GLY 525 422  ?   ?   ?   R . n 
B 2 526 HIS 526 423  ?   ?   ?   R . n 
B 2 527 HIS 527 424  ?   ?   ?   R . n 
B 2 528 HIS 528 425  ?   ?   ?   R . n 
B 2 529 HIS 529 426  ?   ?   ?   R . n 
B 2 530 HIS 530 427  ?   ?   ?   R . n 
B 2 531 HIS 531 428  ?   ?   ?   R . n 
B 2 532 HIS 532 429  ?   ?   ?   R . n 
B 2 533 HIS 533 430  ?   ?   ?   R . n 
B 2 534 HIS 534 431  ?   ?   ?   R . n 
B 2 535 HIS 535 432  ?   ?   ?   R . n 
# 
_pdbx_nonpoly_scheme.asym_id         C 
_pdbx_nonpoly_scheme.entity_id       3 
_pdbx_nonpoly_scheme.mon_id          A1AKO 
_pdbx_nonpoly_scheme.ndb_seq_num     1 
_pdbx_nonpoly_scheme.pdb_seq_num     1201 
_pdbx_nonpoly_scheme.auth_seq_num    1201 
_pdbx_nonpoly_scheme.pdb_mon_id      A1AKO 
_pdbx_nonpoly_scheme.auth_mon_id     LIG 
_pdbx_nonpoly_scheme.pdb_strand_id   R 
_pdbx_nonpoly_scheme.pdb_ins_code    . 
# 
loop_
_pdbx_unobs_or_zero_occ_atoms.id 
_pdbx_unobs_or_zero_occ_atoms.PDB_model_num 
_pdbx_unobs_or_zero_occ_atoms.polymer_flag 
_pdbx_unobs_or_zero_occ_atoms.occupancy_flag 
_pdbx_unobs_or_zero_occ_atoms.auth_asym_id 
_pdbx_unobs_or_zero_occ_atoms.auth_comp_id 
_pdbx_unobs_or_zero_occ_atoms.auth_seq_id 
_pdbx_unobs_or_zero_occ_atoms.PDB_ins_code 
_pdbx_unobs_or_zero_occ_atoms.auth_atom_id 
_pdbx_unobs_or_zero_occ_atoms.label_alt_id 
_pdbx_unobs_or_zero_occ_atoms.label_asym_id 
_pdbx_unobs_or_zero_occ_atoms.label_comp_id 
_pdbx_unobs_or_zero_occ_atoms.label_seq_id 
_pdbx_unobs_or_zero_occ_atoms.label_atom_id 
1  1 Y 1 R MET 109 ? CG  ? B MET 47  CG  
2  1 Y 1 R MET 109 ? SD  ? B MET 47  SD  
3  1 Y 1 R MET 109 ? CE  ? B MET 47  CE  
4  1 Y 1 R ARG 145 ? CG  ? B ARG 83  CG  
5  1 Y 1 R ARG 145 ? CD  ? B ARG 83  CD  
6  1 Y 1 R ARG 145 ? NE  ? B ARG 83  NE  
7  1 Y 1 R ARG 145 ? CZ  ? B ARG 83  CZ  
8  1 Y 1 R ARG 145 ? NH1 ? B ARG 83  NH1 
9  1 Y 1 R ARG 145 ? NH2 ? B ARG 83  NH2 
10 1 Y 1 R ARG 182 ? CG  ? B ARG 120 CG  
11 1 Y 1 R ARG 182 ? CD  ? B ARG 120 CD  
12 1 Y 1 R ARG 182 ? NE  ? B ARG 120 NE  
13 1 Y 1 R ARG 182 ? CZ  ? B ARG 120 CZ  
14 1 Y 1 R ARG 182 ? NH1 ? B ARG 120 NH1 
15 1 Y 1 R ARG 182 ? NH2 ? B ARG 120 NH2 
16 1 Y 1 R GLN 261 ? CG  ? B GLN 199 CG  
17 1 Y 1 R GLN 261 ? CD  ? B GLN 199 CD  
18 1 Y 1 R GLN 261 ? OE1 ? B GLN 199 OE1 
19 1 Y 1 R GLN 261 ? NE2 ? B GLN 199 NE2 
20 1 Y 1 R LYS 370 ? CG  ? B LYS 473 CG  
21 1 Y 1 R LYS 370 ? CD  ? B LYS 473 CD  
22 1 Y 1 R LYS 370 ? CE  ? B LYS 473 CE  
23 1 Y 1 R LYS 370 ? NZ  ? B LYS 473 NZ  
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B9Z 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B9Z 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B9Z 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_refine.aniso_B[1][1]                            ? 
_refine.aniso_B[1][2]                            ? 
_refine.aniso_B[1][3]                            ? 
_refine.aniso_B[2][2]                            ? 
_refine.aniso_B[2][3]                            ? 
_refine.aniso_B[3][3]                            ? 
_refine.B_iso_max                                ? 
_refine.B_iso_mean                               ? 
_refine.B_iso_min                                ? 
_refine.correlation_coeff_Fo_to_Fc               ? 
_refine.correlation_coeff_Fo_to_Fc_free          ? 
_refine.details                                  ? 
_refine.diff_density_max                         ? 
_refine.diff_density_max_esd                     ? 
_refine.diff_density_min                         ? 
_refine.diff_density_min_esd                     ? 
_refine.diff_density_rms                         ? 
_refine.diff_density_rms_esd                     ? 
_refine.entry_id                                 9B9Z 
_refine.pdbx_refine_id                           'ELECTRON MICROSCOPY' 
_refine.ls_abs_structure_details                 ? 
_refine.ls_abs_structure_Flack                   ? 
_refine.ls_abs_structure_Flack_esd               ? 
_refine.ls_abs_structure_Rogers                  ? 
_refine.ls_abs_structure_Rogers_esd              ? 
_refine.ls_d_res_high                            . 
_refine.ls_d_res_low                             ? 
_refine.ls_extinction_coef                       ? 
_refine.ls_extinction_coef_esd                   ? 
_refine.ls_extinction_expression                 ? 
_refine.ls_extinction_method                     ? 
_refine.ls_goodness_of_fit_all                   ? 
_refine.ls_goodness_of_fit_all_esd               ? 
_refine.ls_goodness_of_fit_obs                   ? 
_refine.ls_goodness_of_fit_obs_esd               ? 
_refine.ls_hydrogen_treatment                    ? 
_refine.ls_matrix_type                           ? 
_refine.ls_number_constraints                    ? 
_refine.ls_number_parameters                     ? 
_refine.ls_number_reflns_all                     ? 
_refine.ls_number_reflns_obs                     ? 
_refine.ls_number_reflns_R_free                  ? 
_refine.ls_number_reflns_R_work                  ? 
_refine.ls_number_restraints                     ? 
_refine.ls_percent_reflns_obs                    ? 
_refine.ls_percent_reflns_R_free                 ? 
_refine.ls_R_factor_all                          ? 
_refine.ls_R_factor_obs                          ? 
_refine.ls_R_factor_R_free                       ? 
_refine.ls_R_factor_R_free_error                 ? 
_refine.ls_R_factor_R_free_error_details         ? 
_refine.ls_R_factor_R_work                       ? 
_refine.ls_R_Fsqd_factor_obs                     ? 
_refine.ls_R_I_factor_obs                        ? 
_refine.ls_redundancy_reflns_all                 ? 
_refine.ls_redundancy_reflns_obs                 ? 
_refine.ls_restrained_S_all                      ? 
_refine.ls_restrained_S_obs                      ? 
_refine.ls_shift_over_esd_max                    ? 
_refine.ls_shift_over_esd_mean                   ? 
_refine.ls_structure_factor_coef                 ? 
_refine.ls_weighting_details                     ? 
_refine.ls_weighting_scheme                      ? 
_refine.ls_wR_factor_all                         ? 
_refine.ls_wR_factor_obs                         ? 
_refine.ls_wR_factor_R_free                      ? 
_refine.ls_wR_factor_R_work                      ? 
_refine.occupancy_max                            ? 
_refine.occupancy_min                            ? 
_refine.solvent_model_details                    ? 
_refine.solvent_model_param_bsol                 ? 
_refine.solvent_model_param_ksol                 ? 
_refine.pdbx_R_complete                          ? 
_refine.ls_R_factor_gt                           ? 
_refine.ls_goodness_of_fit_gt                    ? 
_refine.ls_goodness_of_fit_ref                   ? 
_refine.ls_shift_over_su_max                     ? 
_refine.ls_shift_over_su_max_lt                  ? 
_refine.ls_shift_over_su_mean                    ? 
_refine.ls_shift_over_su_mean_lt                 ? 
_refine.pdbx_ls_sigma_I                          ? 
_refine.pdbx_ls_sigma_F                          ? 
_refine.pdbx_ls_sigma_Fsqd                       ? 
_refine.pdbx_data_cutoff_high_absF               ? 
_refine.pdbx_data_cutoff_high_rms_absF           ? 
_refine.pdbx_data_cutoff_low_absF                ? 
_refine.pdbx_isotropic_thermal_model             ? 
_refine.pdbx_ls_cross_valid_method               ? 
_refine.pdbx_method_to_determine_struct          ? 
_refine.pdbx_starting_model                      ? 
_refine.pdbx_stereochemistry_target_values       ? 
_refine.pdbx_R_Free_selection_details            ? 
_refine.pdbx_stereochem_target_val_spec_case     ? 
_refine.pdbx_overall_ESU_R                       ? 
_refine.pdbx_overall_ESU_R_Free                  ? 
_refine.pdbx_solvent_vdw_probe_radii             ? 
_refine.pdbx_solvent_ion_probe_radii             ? 
_refine.pdbx_solvent_shrinkage_radii             ? 
_refine.pdbx_real_space_R                        ? 
_refine.pdbx_density_correlation                 ? 
_refine.pdbx_pd_number_of_powder_patterns        ? 
_refine.pdbx_pd_number_of_points                 ? 
_refine.pdbx_pd_meas_number_of_points            ? 
_refine.pdbx_pd_proc_ls_prof_R_factor            ? 
_refine.pdbx_pd_proc_ls_prof_wR_factor           ? 
_refine.pdbx_pd_Marquardt_correlation_coeff      ? 
_refine.pdbx_pd_Fsqrd_R_factor                   ? 
_refine.pdbx_pd_ls_matrix_band_width             ? 
_refine.pdbx_overall_phase_error                 ? 
_refine.pdbx_overall_SU_R_free_Cruickshank_DPI   ? 
_refine.pdbx_overall_SU_R_free_Blow_DPI          ? 
_refine.pdbx_overall_SU_R_Blow_DPI               ? 
_refine.pdbx_TLS_residual_ADP_flag               ? 
_refine.pdbx_diffrn_id                           ? 
_refine.overall_SU_B                             ? 
_refine.overall_SU_ML                            ? 
_refine.overall_SU_R_Cruickshank_DPI             ? 
_refine.overall_SU_R_free                        ? 
_refine.overall_FOM_free_R_set                   ? 
_refine.overall_FOM_work_R_set                   ? 
_refine.pdbx_average_fsc_overall                 ? 
_refine.pdbx_average_fsc_work                    ? 
_refine.pdbx_average_fsc_free                    ? 
# 
loop_
_refine_ls_restr.pdbx_refine_id 
_refine_ls_restr.criterion 
_refine_ls_restr.dev_ideal 
_refine_ls_restr.dev_ideal_target 
_refine_ls_restr.number 
_refine_ls_restr.rejects 
_refine_ls_restr.type 
_refine_ls_restr.weight 
_refine_ls_restr.pdbx_restraint_function 
'ELECTRON MICROSCOPY' ? 0.004 ? 4851 ? f_bond_d           ? ? 
'ELECTRON MICROSCOPY' ? 0.766 ? 6570 ? f_angle_d          ? ? 
'ELECTRON MICROSCOPY' ? 4.469 ? 682  ? f_dihedral_angle_d ? ? 
'ELECTRON MICROSCOPY' ? 0.049 ? 749  ? f_chiral_restr     ? ? 
'ELECTRON MICROSCOPY' ? 0.007 ? 824  ? f_plane_restr      ? ? 
# 
_struct.entry_id                     9B9Z 
_struct.title                        'Structural mechanism of CB1R binding to peripheral and biased inverse agonists' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B9Z 
_struct_keywords.text            'obesity, membrane protein, nanobody, SIGNALING PROTEIN-IMMUNE SYSTEM complex' 
_struct_keywords.pdbx_keywords   'SIGNALING PROTEIN/IMMUNE SYSTEM' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
C N N 3 ? 
# 
loop_
_struct_ref.id 
_struct_ref.db_name 
_struct_ref.db_code 
_struct_ref.pdbx_db_accession 
_struct_ref.pdbx_db_isoform 
_struct_ref.entity_id 
_struct_ref.pdbx_seq_one_letter_code 
_struct_ref.pdbx_align_begin 
1 PDB 9B9Z         9B9Z   ? 1 ? 1   
2 UNP CNR1_HUMAN   P21554 ? 2 
;IQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFI
DFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGW
NCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKA
;
96  
3 UNP Q9V2J8_PYRAB Q9V2J8 ? 2 
;GIDCSFWNESYLTGSRDERKKSLLSKFGMDEGVTFMFIGRFDRGQKGVDVLLKAIEILSSKKEFQEMRFIIIGKGDPELE
GWARSLEEKHGNVKVITEMLSREFVRELYGSVDFVIIPSYFEPFGLVALEAMCLGAIPIASAVGGLRDIITNETGILVKA
GDPGELANAILKALELSRSDLSKFRENCKKRAMSFS
;
218 
4 UNP CNR1_HUMAN   P21554 ? 2 
;DQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMF
PSCE
;
333 
# 
loop_
_struct_ref_seq.align_id 
_struct_ref_seq.ref_id 
_struct_ref_seq.pdbx_PDB_id_code 
_struct_ref_seq.pdbx_strand_id 
_struct_ref_seq.seq_align_beg 
_struct_ref_seq.pdbx_seq_align_beg_ins_code 
_struct_ref_seq.seq_align_end 
_struct_ref_seq.pdbx_seq_align_end_ins_code 
_struct_ref_seq.pdbx_db_accession 
_struct_ref_seq.db_align_beg 
_struct_ref_seq.pdbx_db_align_beg_ins_code 
_struct_ref_seq.db_align_end 
_struct_ref_seq.pdbx_db_align_end_ins_code 
_struct_ref_seq.pdbx_auth_seq_align_beg 
_struct_ref_seq.pdbx_auth_seq_align_end 
1 1 9B9Z N 1   ? 128 ? 9B9Z   1   ? 128 ? 1    128  
2 2 9B9Z R 34  ? 239 ? P21554 96  ? 301 ? 96   301  
3 3 9B9Z R 240 ? 435 ? Q9V2J8 218 ? 413 ? 1001 1196 
4 4 9B9Z R 436 ? 519 ? P21554 333 ? 416 ? 333  416  
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
2 9B9Z ASP R 1   ? UNP P21554 ?   ?   'expression tag' 63  1  
2 9B9Z TYR R 2   ? UNP P21554 ?   ?   'expression tag' 64  2  
2 9B9Z LYS R 3   ? UNP P21554 ?   ?   'expression tag' 65  3  
2 9B9Z ASP R 4   ? UNP P21554 ?   ?   'expression tag' 66  4  
2 9B9Z ASP R 5   ? UNP P21554 ?   ?   'expression tag' 67  5  
2 9B9Z ASP R 6   ? UNP P21554 ?   ?   'expression tag' 68  6  
2 9B9Z ASP R 7   ? UNP P21554 ?   ?   'expression tag' 69  7  
2 9B9Z ALA R 8   ? UNP P21554 ?   ?   'expression tag' 70  8  
2 9B9Z MET R 9   ? UNP P21554 ?   ?   'expression tag' 71  9  
2 9B9Z ASP R 10  ? UNP P21554 ?   ?   'expression tag' 72  10 
2 9B9Z GLN R 11  ? UNP P21554 ?   ?   'expression tag' 73  11 
2 9B9Z VAL R 12  ? UNP P21554 ?   ?   'expression tag' 74  12 
2 9B9Z ASN R 13  ? UNP P21554 ?   ?   'expression tag' 75  13 
2 9B9Z ILE R 14  ? UNP P21554 ?   ?   'expression tag' 76  14 
2 9B9Z THR R 15  ? UNP P21554 ?   ?   'expression tag' 77  15 
2 9B9Z GLU R 16  ? UNP P21554 ?   ?   'expression tag' 78  16 
2 9B9Z PHE R 17  ? UNP P21554 ?   ?   'expression tag' 79  17 
2 9B9Z TYR R 18  ? UNP P21554 ?   ?   'expression tag' 80  18 
2 9B9Z ASN R 19  ? UNP P21554 ?   ?   'expression tag' 81  19 
2 9B9Z LYS R 20  ? UNP P21554 ?   ?   'expression tag' 82  20 
2 9B9Z SER R 21  ? UNP P21554 ?   ?   'expression tag' 83  21 
2 9B9Z LEU R 22  ? UNP P21554 ?   ?   'expression tag' 84  22 
2 9B9Z SER R 23  ? UNP P21554 ?   ?   'expression tag' 85  23 
2 9B9Z SER R 24  ? UNP P21554 ?   ?   'expression tag' 86  24 
2 9B9Z PHE R 25  ? UNP P21554 ?   ?   'expression tag' 87  25 
2 9B9Z GLU R 26  ? UNP P21554 ?   ?   'expression tag' 88  26 
2 9B9Z ASN R 27  ? UNP P21554 ?   ?   'expression tag' 89  27 
2 9B9Z LEU R 28  ? UNP P21554 ?   ?   'expression tag' 90  28 
2 9B9Z TYR R 29  ? UNP P21554 ?   ?   'expression tag' 91  29 
2 9B9Z PHE R 30  ? UNP P21554 ?   ?   'expression tag' 92  30 
2 9B9Z GLN R 31  ? UNP P21554 ?   ?   'expression tag' 93  31 
2 9B9Z GLY R 32  ? UNP P21554 ?   ?   'expression tag' 94  32 
2 9B9Z GLY R 33  ? UNP P21554 ?   ?   'expression tag' 95  33 
2 9B9Z LYS R 141 ? UNP P21554 SER 203 conflict         203 34 
2 9B9Z ALA R 148 ? UNP P21554 THR 210 conflict         210 35 
2 9B9Z LYS R 211 ? UNP P21554 GLU 273 conflict         273 36 
2 9B9Z VAL R 221 ? UNP P21554 THR 283 conflict         283 37 
4 9B9Z GLU R 443 ? UNP P21554 ARG 340 conflict         340 38 
4 9B9Z ASN R 520 ? UNP P21554 ?   ?   'expression tag' 417 39 
4 9B9Z LEU R 521 ? UNP P21554 ?   ?   'expression tag' 418 40 
4 9B9Z TYR R 522 ? UNP P21554 ?   ?   'expression tag' 419 41 
4 9B9Z PHE R 523 ? UNP P21554 ?   ?   'expression tag' 420 42 
4 9B9Z GLN R 524 ? UNP P21554 ?   ?   'expression tag' 421 43 
4 9B9Z GLY R 525 ? UNP P21554 ?   ?   'expression tag' 422 44 
4 9B9Z HIS R 526 ? UNP P21554 ?   ?   'expression tag' 423 45 
4 9B9Z HIS R 527 ? UNP P21554 ?   ?   'expression tag' 424 46 
4 9B9Z HIS R 528 ? UNP P21554 ?   ?   'expression tag' 425 47 
4 9B9Z HIS R 529 ? UNP P21554 ?   ?   'expression tag' 426 48 
4 9B9Z HIS R 530 ? UNP P21554 ?   ?   'expression tag' 427 49 
4 9B9Z HIS R 531 ? UNP P21554 ?   ?   'expression tag' 428 50 
4 9B9Z HIS R 532 ? UNP P21554 ?   ?   'expression tag' 429 51 
4 9B9Z HIS R 533 ? UNP P21554 ?   ?   'expression tag' 430 52 
4 9B9Z HIS R 534 ? UNP P21554 ?   ?   'expression tag' 431 53 
4 9B9Z HIS R 535 ? UNP P21554 ?   ?   'expression tag' 432 54 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_and_software_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   dimeric 
_pdbx_struct_assembly.oligomeric_count     2 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B,C 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 ASN B 50  ? HIS B 81  ? ASN R 112  HIS R 143  1 ? 32 
HELX_P HELX_P2  AA2 SER B 82  ? CYS B 87  ? SER R 144  CYS R 149  1 ? 6  
HELX_P HELX_P3  AA3 ARG B 88  ? SER B 90  ? ARG R 150  SER R 152  5 ? 3  
HELX_P HELX_P4  AA4 TYR B 91  ? ASP B 114 ? TYR R 153  ASP R 176  1 ? 24 
HELX_P HELX_P5  AA5 SER B 123 ? ARG B 158 ? SER R 185  ARG R 220  1 ? 36 
HELX_P HELX_P6  AA6 ARG B 158 ? VAL B 166 ? ARG R 220  VAL R 228  1 ? 9  
HELX_P HELX_P7  AA7 THR B 167 ? LEU B 188 ? THR R 229  LEU R 250  1 ? 22 
HELX_P HELX_P8  AA8 PRO B 189 ? GLY B 192 ? PRO R 251  GLY R 254  5 ? 4  
HELX_P HELX_P9  AA9 ASN B 194 ? GLN B 199 ? ASN R 256  GLN R 261  1 ? 6  
HELX_P HELX_P10 AB1 ASP B 210 ? SER B 244 ? ASP R 272  SER R 1005 1 ? 35 
HELX_P HELX_P11 AB2 ASN B 247 ? LEU B 251 ? ASN R 1008 LEU R 1012 5 ? 5  
HELX_P HELX_P12 AB3 SER B 254 ? PHE B 266 ? SER R 1015 PHE R 1027 1 ? 13 
HELX_P HELX_P13 AB4 GLY B 286 ? SER B 298 ? GLY R 1047 SER R 1059 1 ? 13 
HELX_P HELX_P14 AB5 GLU B 302 ? GLN B 304 ? GLU R 1063 GLN R 1065 5 ? 3  
HELX_P HELX_P15 AB6 ASP B 315 ? HIS B 329 ? ASP R 1076 HIS R 1090 1 ? 15 
HELX_P HELX_P16 AB7 SER B 340 ? GLY B 349 ? SER R 1101 GLY R 1110 1 ? 10 
HELX_P HELX_P17 AB8 GLY B 364 ? LEU B 373 ? GLY R 1125 LEU R 1134 1 ? 10 
HELX_P HELX_P18 AB9 VAL B 382 ? ARG B 386 ? VAL R 1143 ARG R 1147 5 ? 5  
HELX_P HELX_P19 AC1 ASP B 401 ? SER B 416 ? ASP R 1162 SER R 1177 1 ? 16 
HELX_P HELX_P20 AC2 LEU B 420 ? SER B 433 ? LEU R 1181 SER R 1194 1 ? 14 
HELX_P HELX_P21 AC3 SER B 435 ? PHE B 471 ? SER R 1196 PHE R 368  1 ? 37 
HELX_P HELX_P22 AC4 ASN B 475 ? SER B 486 ? ASN R 372  SER R 383  1 ? 12 
HELX_P HELX_P23 AC5 MET B 487 ? SER B 504 ? MET R 384  SER R 401  1 ? 18 
HELX_P HELX_P24 AC6 SER B 504 ? ARG B 512 ? SER R 401  ARG R 409  1 ? 9  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ? ? A CYS 22  SG ? ? ? 1_555 A CYS 95  SG ? ? N CYS 22  N CYS 95  1_555 ? ? ? ? ? ? ? 2.032 ? ? 
disulf2 disulf ? ? B CYS 195 SG ? ? ? 1_555 B CYS 202 SG ? ? R CYS 257 R CYS 264 1_555 ? ? ? ? ? ? ? 2.036 ? ? 
# 
_struct_conn_type.id          disulf 
_struct_conn_type.criteria    ? 
_struct_conn_type.reference   ? 
# 
loop_
_pdbx_modification_feature.ordinal 
_pdbx_modification_feature.label_comp_id 
_pdbx_modification_feature.label_asym_id 
_pdbx_modification_feature.label_seq_id 
_pdbx_modification_feature.label_alt_id 
_pdbx_modification_feature.modified_residue_label_comp_id 
_pdbx_modification_feature.modified_residue_label_asym_id 
_pdbx_modification_feature.modified_residue_label_seq_id 
_pdbx_modification_feature.modified_residue_label_alt_id 
_pdbx_modification_feature.auth_comp_id 
_pdbx_modification_feature.auth_asym_id 
_pdbx_modification_feature.auth_seq_id 
_pdbx_modification_feature.PDB_ins_code 
_pdbx_modification_feature.symmetry 
_pdbx_modification_feature.modified_residue_auth_comp_id 
_pdbx_modification_feature.modified_residue_auth_asym_id 
_pdbx_modification_feature.modified_residue_auth_seq_id 
_pdbx_modification_feature.modified_residue_PDB_ins_code 
_pdbx_modification_feature.modified_residue_symmetry 
_pdbx_modification_feature.comp_id_linking_atom 
_pdbx_modification_feature.modified_residue_id_linking_atom 
_pdbx_modification_feature.modified_residue_id 
_pdbx_modification_feature.ref_pcm_id 
_pdbx_modification_feature.ref_comp_id 
_pdbx_modification_feature.type 
_pdbx_modification_feature.category 
1 CYS A 22  ? CYS A 95  ? CYS N 22  ? 1_555 CYS N 95  ? 1_555 SG SG . . . None 'Disulfide bridge' 
2 CYS B 195 ? CYS B 202 ? CYS R 257 ? 1_555 CYS R 264 ? 1_555 SG SG . . . None 'Disulfide bridge' 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 4 ? 
AA2 ? 6 ? 
AA3 ? 4 ? 
AA4 ? 6 ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1 2 ? anti-parallel 
AA1 2 3 ? anti-parallel 
AA1 3 4 ? anti-parallel 
AA2 1 2 ? parallel      
AA2 2 3 ? anti-parallel 
AA2 3 4 ? anti-parallel 
AA2 4 5 ? anti-parallel 
AA2 5 6 ? anti-parallel 
AA3 1 2 ? parallel      
AA3 2 3 ? anti-parallel 
AA3 3 4 ? anti-parallel 
AA4 1 2 ? parallel      
AA4 2 3 ? parallel      
AA4 3 4 ? parallel      
AA4 4 5 ? parallel      
AA4 5 6 ? parallel      
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1 GLN A 3   ? SER A 7   ? GLN N 3    SER N 7    
AA1 2 SER A 17  ? SER A 25  ? SER N 17   SER N 25   
AA1 3 THR A 77  ? ASN A 83  ? THR N 77   ASN N 83   
AA1 4 PHE A 67  ? ASP A 72  ? PHE N 67   ASP N 72   
AA2 1 GLY A 10  ? GLN A 13  ? GLY N 10   GLN N 13   
AA2 2 THR A 116 ? SER A 121 ? THR N 116  SER N 121  
AA2 3 ALA A 91  ? LEU A 100 ? ALA N 91   LEU N 100  
AA2 4 VAL A 33  ? GLN A 39  ? VAL N 33   GLN N 39   
AA2 5 ARG A 45  ? ILE A 51  ? ARG N 45   ILE N 51   
AA2 6 TYR A 58  ? TYR A 59  ? TYR N 58   TYR N 59   
AA3 1 GLY A 10  ? GLN A 13  ? GLY N 10   GLN N 13   
AA3 2 THR A 116 ? SER A 121 ? THR N 116  SER N 121  
AA3 3 ALA A 91  ? LEU A 100 ? ALA N 91   LEU N 100  
AA3 4 TYR A 108 ? TRP A 112 ? TYR N 108  TRP N 112  
AA4 1 VAL B 332 ? ILE B 335 ? VAL R 1093 ILE R 1096 
AA4 2 MET B 306 ? ILE B 311 ? MET R 1067 ILE R 1072 
AA4 3 VAL B 272 ? ILE B 277 ? VAL R 1033 ILE R 1038 
AA4 4 PHE B 353 ? ILE B 356 ? PHE R 1114 ILE R 1117 
AA4 5 ILE B 376 ? SER B 380 ? ILE R 1137 SER R 1141 
AA4 6 ILE B 395 ? VAL B 397 ? ILE R 1156 VAL R 1158 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1 2 N SER A 7   ? N SER N 7    O SER A 21  ? O SER N 21   
AA1 2 3 N CYS A 22  ? N CYS N 22   O VAL A 78  ? O VAL N 78   
AA1 3 4 O GLN A 81  ? O GLN N 81   N THR A 68  ? N THR N 68   
AA2 1 2 N GLY A 10  ? N GLY N 10   O THR A 119 ? O THR N 119  
AA2 2 3 O THR A 116 ? O THR N 116  N TYR A 93  ? N TYR N 93   
AA2 3 4 O GLU A 98  ? O GLU N 98   N VAL A 33  ? N VAL N 33   
AA2 4 5 N MET A 34  ? N MET N 34   O ILE A 51  ? O ILE N 51   
AA2 5 6 N GLY A 50  ? N GLY N 50   O TYR A 58  ? O TYR N 58   
AA3 1 2 N GLY A 10  ? N GLY N 10   O THR A 119 ? O THR N 119  
AA3 2 3 O THR A 116 ? O THR N 116  N TYR A 93  ? N TYR N 93   
AA3 3 4 N VAL A 99  ? N VAL N 99   O HIS A 109 ? O HIS N 109  
AA4 1 2 O LYS B 333 ? O LYS R 1094 N PHE B 308 ? N PHE R 1069 
AA4 2 3 O ILE B 311 ? O ILE R 1072 N PHE B 276 ? N PHE R 1037 
AA4 3 4 N MET B 275 ? N MET R 1036 O ILE B 355 ? O ILE R 1116 
AA4 4 5 N VAL B 354 ? N VAL R 1115 O ILE B 378 ? O ILE R 1139 
AA4 5 6 N PRO B 377 ? N PRO R 1138 O ILE B 395 ? O ILE R 1156 
# 
_pdbx_entry_details.entry_id                   9B9Z 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
_pdbx_validate_rmsd_angle.id                         1 
_pdbx_validate_rmsd_angle.PDB_model_num              1 
_pdbx_validate_rmsd_angle.auth_atom_id_1             CB 
_pdbx_validate_rmsd_angle.auth_asym_id_1             N 
_pdbx_validate_rmsd_angle.auth_comp_id_1             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_1              72 
_pdbx_validate_rmsd_angle.PDB_ins_code_1             ? 
_pdbx_validate_rmsd_angle.label_alt_id_1             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_2             CG 
_pdbx_validate_rmsd_angle.auth_asym_id_2             N 
_pdbx_validate_rmsd_angle.auth_comp_id_2             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_2              72 
_pdbx_validate_rmsd_angle.PDB_ins_code_2             ? 
_pdbx_validate_rmsd_angle.label_alt_id_2             ? 
_pdbx_validate_rmsd_angle.auth_atom_id_3             OD2 
_pdbx_validate_rmsd_angle.auth_asym_id_3             N 
_pdbx_validate_rmsd_angle.auth_comp_id_3             ASP 
_pdbx_validate_rmsd_angle.auth_seq_id_3              72 
_pdbx_validate_rmsd_angle.PDB_ins_code_3             ? 
_pdbx_validate_rmsd_angle.label_alt_id_3             ? 
_pdbx_validate_rmsd_angle.angle_value                123.79 
_pdbx_validate_rmsd_angle.angle_target_value         118.30 
_pdbx_validate_rmsd_angle.angle_deviation            5.49 
_pdbx_validate_rmsd_angle.angle_standard_deviation   0.90 
_pdbx_validate_rmsd_angle.linker_flag                N 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1 1 PHE N 29   ? ? 67.04   -6.03   
2 1 ALA N 55   ? ? -93.51  53.28   
3 1 MET R 109  ? ? -66.80  6.38    
4 1 SER R 1015 ? ? -126.28 -169.24 
5 1 PRO R 1118 ? ? -89.47  47.62   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B9Z 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B9Z 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.3 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               625709 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            7.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               'MULTIPLE SOURCES' 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'CB1-Nanobody complex' 
_em_entity_assembly.details              ? 
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       '1, 2' 
# 
_em_imaging.entry_id                        9B9Z 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'TFS KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1400 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9B9Z 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            'FEI VITROBOT MARK IV' 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B9Z 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1  1 Y 1 N GLN 1   ? A GLN 1   
2  1 Y 1 N HIS 125 ? A HIS 125 
3  1 Y 1 N HIS 126 ? A HIS 126 
4  1 Y 1 N HIS 127 ? A HIS 127 
5  1 Y 1 N HIS 128 ? A HIS 128 
6  1 Y 1 R ASP 63  ? B ASP 1   
7  1 Y 1 R TYR 64  ? B TYR 2   
8  1 Y 1 R LYS 65  ? B LYS 3   
9  1 Y 1 R ASP 66  ? B ASP 4   
10 1 Y 1 R ASP 67  ? B ASP 5   
11 1 Y 1 R ASP 68  ? B ASP 6   
12 1 Y 1 R ASP 69  ? B ASP 7   
13 1 Y 1 R ALA 70  ? B ALA 8   
14 1 Y 1 R MET 71  ? B MET 9   
15 1 Y 1 R ASP 72  ? B ASP 10  
16 1 Y 1 R GLN 73  ? B GLN 11  
17 1 Y 1 R VAL 74  ? B VAL 12  
18 1 Y 1 R ASN 75  ? B ASN 13  
19 1 Y 1 R ILE 76  ? B ILE 14  
20 1 Y 1 R THR 77  ? B THR 15  
21 1 Y 1 R GLU 78  ? B GLU 16  
22 1 Y 1 R PHE 79  ? B PHE 17  
23 1 Y 1 R TYR 80  ? B TYR 18  
24 1 Y 1 R ASN 81  ? B ASN 19  
25 1 Y 1 R LYS 82  ? B LYS 20  
26 1 Y 1 R SER 83  ? B SER 21  
27 1 Y 1 R LEU 84  ? B LEU 22  
28 1 Y 1 R SER 85  ? B SER 23  
29 1 Y 1 R SER 86  ? B SER 24  
30 1 Y 1 R PHE 87  ? B PHE 25  
31 1 Y 1 R GLU 88  ? B GLU 26  
32 1 Y 1 R ASN 89  ? B ASN 27  
33 1 Y 1 R LEU 90  ? B LEU 28  
34 1 Y 1 R TYR 91  ? B TYR 29  
35 1 Y 1 R PHE 92  ? B PHE 30  
36 1 Y 1 R GLN 93  ? B GLN 31  
37 1 Y 1 R GLY 94  ? B GLY 32  
38 1 Y 1 R GLY 95  ? B GLY 33  
39 1 Y 1 R ILE 96  ? B ILE 34  
40 1 Y 1 R GLN 97  ? B GLN 35  
41 1 Y 1 R CYS 98  ? B CYS 36  
42 1 Y 1 R GLY 99  ? B GLY 37  
43 1 Y 1 R PRO 413 ? B PRO 516 
44 1 Y 1 R SER 414 ? B SER 517 
45 1 Y 1 R CYS 415 ? B CYS 518 
46 1 Y 1 R GLU 416 ? B GLU 519 
47 1 Y 1 R ASN 417 ? B ASN 520 
48 1 Y 1 R LEU 418 ? B LEU 521 
49 1 Y 1 R TYR 419 ? B TYR 522 
50 1 Y 1 R PHE 420 ? B PHE 523 
51 1 Y 1 R GLN 421 ? B GLN 524 
52 1 Y 1 R GLY 422 ? B GLY 525 
53 1 Y 1 R HIS 423 ? B HIS 526 
54 1 Y 1 R HIS 424 ? B HIS 527 
55 1 Y 1 R HIS 425 ? B HIS 528 
56 1 Y 1 R HIS 426 ? B HIS 529 
57 1 Y 1 R HIS 427 ? B HIS 530 
58 1 Y 1 R HIS 428 ? B HIS 531 
59 1 Y 1 R HIS 429 ? B HIS 532 
60 1 Y 1 R HIS 430 ? B HIS 533 
61 1 Y 1 R HIS 431 ? B HIS 534 
62 1 Y 1 R HIS 432 ? B HIS 535 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
A1AKO N3   N  N N 1   
A1AKO C4   C  N N 2   
A1AKO C7   C  N N 3   
A1AKO C8   C  Y N 4   
A1AKO C10  C  Y N 5   
A1AKO C13  C  Y N 6   
A1AKO C15  C  N S 7   
A1AKO C17  C  Y N 8   
A1AKO C20  C  Y N 9   
A1AKO C21  C  Y N 10  
A1AKO C22  C  N N 11  
A1AKO C24  C  N N 12  
A1AKO C26  C  N N 13  
A1AKO C28  C  Y N 14  
A1AKO C11  C  Y N 15  
A1AKO C14  C  Y N 16  
A1AKO C16  C  Y N 17  
A1AKO C18  C  Y N 18  
A1AKO C19  C  Y N 19  
A1AKO C27  C  Y N 20  
A1AKO C29  C  Y N 21  
A1AKO C30  C  Y N 22  
A1AKO C31  C  N N 23  
A1AKO C35  C  Y N 24  
A1AKO C36  C  Y N 25  
A1AKO C9   C  Y N 26  
A1AKO F32  F  N N 27  
A1AKO F33  F  N N 28  
A1AKO F34  F  N N 29  
A1AKO N23  N  N N 30  
A1AKO N25  N  N N 31  
A1AKO N5   N  N N 32  
A1AKO N6   N  N N 33  
A1AKO O1   O  N N 34  
A1AKO O37  O  N N 35  
A1AKO S2   S  N N 36  
A1AKO CL1  CL N N 37  
A1AKO H1   H  N N 38  
A1AKO H3   H  N N 39  
A1AKO H4   H  N N 40  
A1AKO H5   H  N N 41  
A1AKO H6   H  N N 42  
A1AKO H7   H  N N 43  
A1AKO H8   H  N N 44  
A1AKO H9   H  N N 45  
A1AKO H10  H  N N 46  
A1AKO H11  H  N N 47  
A1AKO H12  H  N N 48  
A1AKO H13  H  N N 49  
A1AKO H14  H  N N 50  
A1AKO H15  H  N N 51  
A1AKO H16  H  N N 52  
A1AKO H17  H  N N 53  
A1AKO H18  H  N N 54  
A1AKO H19  H  N N 55  
A1AKO H20  H  N N 56  
A1AKO H21  H  N N 57  
A1AKO H22  H  N N 58  
ALA   N    N  N N 59  
ALA   CA   C  N S 60  
ALA   C    C  N N 61  
ALA   O    O  N N 62  
ALA   CB   C  N N 63  
ALA   OXT  O  N N 64  
ALA   H    H  N N 65  
ALA   H2   H  N N 66  
ALA   HA   H  N N 67  
ALA   HB1  H  N N 68  
ALA   HB2  H  N N 69  
ALA   HB3  H  N N 70  
ALA   HXT  H  N N 71  
ARG   N    N  N N 72  
ARG   CA   C  N S 73  
ARG   C    C  N N 74  
ARG   O    O  N N 75  
ARG   CB   C  N N 76  
ARG   CG   C  N N 77  
ARG   CD   C  N N 78  
ARG   NE   N  N N 79  
ARG   CZ   C  N N 80  
ARG   NH1  N  N N 81  
ARG   NH2  N  N N 82  
ARG   OXT  O  N N 83  
ARG   H    H  N N 84  
ARG   H2   H  N N 85  
ARG   HA   H  N N 86  
ARG   HB2  H  N N 87  
ARG   HB3  H  N N 88  
ARG   HG2  H  N N 89  
ARG   HG3  H  N N 90  
ARG   HD2  H  N N 91  
ARG   HD3  H  N N 92  
ARG   HE   H  N N 93  
ARG   HH11 H  N N 94  
ARG   HH12 H  N N 95  
ARG   HH21 H  N N 96  
ARG   HH22 H  N N 97  
ARG   HXT  H  N N 98  
ASN   N    N  N N 99  
ASN   CA   C  N S 100 
ASN   C    C  N N 101 
ASN   O    O  N N 102 
ASN   CB   C  N N 103 
ASN   CG   C  N N 104 
ASN   OD1  O  N N 105 
ASN   ND2  N  N N 106 
ASN   OXT  O  N N 107 
ASN   H    H  N N 108 
ASN   H2   H  N N 109 
ASN   HA   H  N N 110 
ASN   HB2  H  N N 111 
ASN   HB3  H  N N 112 
ASN   HD21 H  N N 113 
ASN   HD22 H  N N 114 
ASN   HXT  H  N N 115 
ASP   N    N  N N 116 
ASP   CA   C  N S 117 
ASP   C    C  N N 118 
ASP   O    O  N N 119 
ASP   CB   C  N N 120 
ASP   CG   C  N N 121 
ASP   OD1  O  N N 122 
ASP   OD2  O  N N 123 
ASP   OXT  O  N N 124 
ASP   H    H  N N 125 
ASP   H2   H  N N 126 
ASP   HA   H  N N 127 
ASP   HB2  H  N N 128 
ASP   HB3  H  N N 129 
ASP   HD2  H  N N 130 
ASP   HXT  H  N N 131 
CYS   N    N  N N 132 
CYS   CA   C  N R 133 
CYS   C    C  N N 134 
CYS   O    O  N N 135 
CYS   CB   C  N N 136 
CYS   SG   S  N N 137 
CYS   OXT  O  N N 138 
CYS   H    H  N N 139 
CYS   H2   H  N N 140 
CYS   HA   H  N N 141 
CYS   HB2  H  N N 142 
CYS   HB3  H  N N 143 
CYS   HG   H  N N 144 
CYS   HXT  H  N N 145 
GLN   N    N  N N 146 
GLN   CA   C  N S 147 
GLN   C    C  N N 148 
GLN   O    O  N N 149 
GLN   CB   C  N N 150 
GLN   CG   C  N N 151 
GLN   CD   C  N N 152 
GLN   OE1  O  N N 153 
GLN   NE2  N  N N 154 
GLN   OXT  O  N N 155 
GLN   H    H  N N 156 
GLN   H2   H  N N 157 
GLN   HA   H  N N 158 
GLN   HB2  H  N N 159 
GLN   HB3  H  N N 160 
GLN   HG2  H  N N 161 
GLN   HG3  H  N N 162 
GLN   HE21 H  N N 163 
GLN   HE22 H  N N 164 
GLN   HXT  H  N N 165 
GLU   N    N  N N 166 
GLU   CA   C  N S 167 
GLU   C    C  N N 168 
GLU   O    O  N N 169 
GLU   CB   C  N N 170 
GLU   CG   C  N N 171 
GLU   CD   C  N N 172 
GLU   OE1  O  N N 173 
GLU   OE2  O  N N 174 
GLU   OXT  O  N N 175 
GLU   H    H  N N 176 
GLU   H2   H  N N 177 
GLU   HA   H  N N 178 
GLU   HB2  H  N N 179 
GLU   HB3  H  N N 180 
GLU   HG2  H  N N 181 
GLU   HG3  H  N N 182 
GLU   HE2  H  N N 183 
GLU   HXT  H  N N 184 
GLY   N    N  N N 185 
GLY   CA   C  N N 186 
GLY   C    C  N N 187 
GLY   O    O  N N 188 
GLY   OXT  O  N N 189 
GLY   H    H  N N 190 
GLY   H2   H  N N 191 
GLY   HA2  H  N N 192 
GLY   HA3  H  N N 193 
GLY   HXT  H  N N 194 
HIS   N    N  N N 195 
HIS   CA   C  N S 196 
HIS   C    C  N N 197 
HIS   O    O  N N 198 
HIS   CB   C  N N 199 
HIS   CG   C  Y N 200 
HIS   ND1  N  Y N 201 
HIS   CD2  C  Y N 202 
HIS   CE1  C  Y N 203 
HIS   NE2  N  Y N 204 
HIS   OXT  O  N N 205 
HIS   H    H  N N 206 
HIS   H2   H  N N 207 
HIS   HA   H  N N 208 
HIS   HB2  H  N N 209 
HIS   HB3  H  N N 210 
HIS   HD1  H  N N 211 
HIS   HD2  H  N N 212 
HIS   HE1  H  N N 213 
HIS   HE2  H  N N 214 
HIS   HXT  H  N N 215 
ILE   N    N  N N 216 
ILE   CA   C  N S 217 
ILE   C    C  N N 218 
ILE   O    O  N N 219 
ILE   CB   C  N S 220 
ILE   CG1  C  N N 221 
ILE   CG2  C  N N 222 
ILE   CD1  C  N N 223 
ILE   OXT  O  N N 224 
ILE   H    H  N N 225 
ILE   H2   H  N N 226 
ILE   HA   H  N N 227 
ILE   HB   H  N N 228 
ILE   HG12 H  N N 229 
ILE   HG13 H  N N 230 
ILE   HG21 H  N N 231 
ILE   HG22 H  N N 232 
ILE   HG23 H  N N 233 
ILE   HD11 H  N N 234 
ILE   HD12 H  N N 235 
ILE   HD13 H  N N 236 
ILE   HXT  H  N N 237 
LEU   N    N  N N 238 
LEU   CA   C  N S 239 
LEU   C    C  N N 240 
LEU   O    O  N N 241 
LEU   CB   C  N N 242 
LEU   CG   C  N N 243 
LEU   CD1  C  N N 244 
LEU   CD2  C  N N 245 
LEU   OXT  O  N N 246 
LEU   H    H  N N 247 
LEU   H2   H  N N 248 
LEU   HA   H  N N 249 
LEU   HB2  H  N N 250 
LEU   HB3  H  N N 251 
LEU   HG   H  N N 252 
LEU   HD11 H  N N 253 
LEU   HD12 H  N N 254 
LEU   HD13 H  N N 255 
LEU   HD21 H  N N 256 
LEU   HD22 H  N N 257 
LEU   HD23 H  N N 258 
LEU   HXT  H  N N 259 
LYS   N    N  N N 260 
LYS   CA   C  N S 261 
LYS   C    C  N N 262 
LYS   O    O  N N 263 
LYS   CB   C  N N 264 
LYS   CG   C  N N 265 
LYS   CD   C  N N 266 
LYS   CE   C  N N 267 
LYS   NZ   N  N N 268 
LYS   OXT  O  N N 269 
LYS   H    H  N N 270 
LYS   H2   H  N N 271 
LYS   HA   H  N N 272 
LYS   HB2  H  N N 273 
LYS   HB3  H  N N 274 
LYS   HG2  H  N N 275 
LYS   HG3  H  N N 276 
LYS   HD2  H  N N 277 
LYS   HD3  H  N N 278 
LYS   HE2  H  N N 279 
LYS   HE3  H  N N 280 
LYS   HZ1  H  N N 281 
LYS   HZ2  H  N N 282 
LYS   HZ3  H  N N 283 
LYS   HXT  H  N N 284 
MET   N    N  N N 285 
MET   CA   C  N S 286 
MET   C    C  N N 287 
MET   O    O  N N 288 
MET   CB   C  N N 289 
MET   CG   C  N N 290 
MET   SD   S  N N 291 
MET   CE   C  N N 292 
MET   OXT  O  N N 293 
MET   H    H  N N 294 
MET   H2   H  N N 295 
MET   HA   H  N N 296 
MET   HB2  H  N N 297 
MET   HB3  H  N N 298 
MET   HG2  H  N N 299 
MET   HG3  H  N N 300 
MET   HE1  H  N N 301 
MET   HE2  H  N N 302 
MET   HE3  H  N N 303 
MET   HXT  H  N N 304 
PHE   N    N  N N 305 
PHE   CA   C  N S 306 
PHE   C    C  N N 307 
PHE   O    O  N N 308 
PHE   CB   C  N N 309 
PHE   CG   C  Y N 310 
PHE   CD1  C  Y N 311 
PHE   CD2  C  Y N 312 
PHE   CE1  C  Y N 313 
PHE   CE2  C  Y N 314 
PHE   CZ   C  Y N 315 
PHE   OXT  O  N N 316 
PHE   H    H  N N 317 
PHE   H2   H  N N 318 
PHE   HA   H  N N 319 
PHE   HB2  H  N N 320 
PHE   HB3  H  N N 321 
PHE   HD1  H  N N 322 
PHE   HD2  H  N N 323 
PHE   HE1  H  N N 324 
PHE   HE2  H  N N 325 
PHE   HZ   H  N N 326 
PHE   HXT  H  N N 327 
PRO   N    N  N N 328 
PRO   CA   C  N S 329 
PRO   C    C  N N 330 
PRO   O    O  N N 331 
PRO   CB   C  N N 332 
PRO   CG   C  N N 333 
PRO   CD   C  N N 334 
PRO   OXT  O  N N 335 
PRO   H    H  N N 336 
PRO   HA   H  N N 337 
PRO   HB2  H  N N 338 
PRO   HB3  H  N N 339 
PRO   HG2  H  N N 340 
PRO   HG3  H  N N 341 
PRO   HD2  H  N N 342 
PRO   HD3  H  N N 343 
PRO   HXT  H  N N 344 
SER   N    N  N N 345 
SER   CA   C  N S 346 
SER   C    C  N N 347 
SER   O    O  N N 348 
SER   CB   C  N N 349 
SER   OG   O  N N 350 
SER   OXT  O  N N 351 
SER   H    H  N N 352 
SER   H2   H  N N 353 
SER   HA   H  N N 354 
SER   HB2  H  N N 355 
SER   HB3  H  N N 356 
SER   HG   H  N N 357 
SER   HXT  H  N N 358 
THR   N    N  N N 359 
THR   CA   C  N S 360 
THR   C    C  N N 361 
THR   O    O  N N 362 
THR   CB   C  N R 363 
THR   OG1  O  N N 364 
THR   CG2  C  N N 365 
THR   OXT  O  N N 366 
THR   H    H  N N 367 
THR   H2   H  N N 368 
THR   HA   H  N N 369 
THR   HB   H  N N 370 
THR   HG1  H  N N 371 
THR   HG21 H  N N 372 
THR   HG22 H  N N 373 
THR   HG23 H  N N 374 
THR   HXT  H  N N 375 
TRP   N    N  N N 376 
TRP   CA   C  N S 377 
TRP   C    C  N N 378 
TRP   O    O  N N 379 
TRP   CB   C  N N 380 
TRP   CG   C  Y N 381 
TRP   CD1  C  Y N 382 
TRP   CD2  C  Y N 383 
TRP   NE1  N  Y N 384 
TRP   CE2  C  Y N 385 
TRP   CE3  C  Y N 386 
TRP   CZ2  C  Y N 387 
TRP   CZ3  C  Y N 388 
TRP   CH2  C  Y N 389 
TRP   OXT  O  N N 390 
TRP   H    H  N N 391 
TRP   H2   H  N N 392 
TRP   HA   H  N N 393 
TRP   HB2  H  N N 394 
TRP   HB3  H  N N 395 
TRP   HD1  H  N N 396 
TRP   HE1  H  N N 397 
TRP   HE3  H  N N 398 
TRP   HZ2  H  N N 399 
TRP   HZ3  H  N N 400 
TRP   HH2  H  N N 401 
TRP   HXT  H  N N 402 
TYR   N    N  N N 403 
TYR   CA   C  N S 404 
TYR   C    C  N N 405 
TYR   O    O  N N 406 
TYR   CB   C  N N 407 
TYR   CG   C  Y N 408 
TYR   CD1  C  Y N 409 
TYR   CD2  C  Y N 410 
TYR   CE1  C  Y N 411 
TYR   CE2  C  Y N 412 
TYR   CZ   C  Y N 413 
TYR   OH   O  N N 414 
TYR   OXT  O  N N 415 
TYR   H    H  N N 416 
TYR   H2   H  N N 417 
TYR   HA   H  N N 418 
TYR   HB2  H  N N 419 
TYR   HB3  H  N N 420 
TYR   HD1  H  N N 421 
TYR   HD2  H  N N 422 
TYR   HE1  H  N N 423 
TYR   HE2  H  N N 424 
TYR   HH   H  N N 425 
TYR   HXT  H  N N 426 
VAL   N    N  N N 427 
VAL   CA   C  N S 428 
VAL   C    C  N N 429 
VAL   O    O  N N 430 
VAL   CB   C  N N 431 
VAL   CG1  C  N N 432 
VAL   CG2  C  N N 433 
VAL   OXT  O  N N 434 
VAL   H    H  N N 435 
VAL   H2   H  N N 436 
VAL   HA   H  N N 437 
VAL   HB   H  N N 438 
VAL   HG11 H  N N 439 
VAL   HG12 H  N N 440 
VAL   HG13 H  N N 441 
VAL   HG21 H  N N 442 
VAL   HG22 H  N N 443 
VAL   HG23 H  N N 444 
VAL   HXT  H  N N 445 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
A1AKO O37 S2   doub N N 1   
A1AKO F33 C31  sing N N 2   
A1AKO O1  S2   doub N N 3   
A1AKO C36 C35  doub Y N 4   
A1AKO C36 C27  sing Y N 5   
A1AKO C35 C30  sing Y N 6   
A1AKO S2  C27  sing N N 7   
A1AKO S2  N3   sing N N 8   
A1AKO C27 C28  doub Y N 9   
A1AKO C26 C24  sing N N 10  
A1AKO C30 C31  sing N N 11  
A1AKO C30 C29  doub Y N 12  
A1AKO C31 F34  sing N N 13  
A1AKO C31 F32  sing N N 14  
A1AKO C28 C29  sing Y N 15  
A1AKO C24 N25  doub N N 16  
A1AKO C24 N23  sing N N 17  
A1AKO N23 C4   doub N N 18  
A1AKO N3  C4   sing N N 19  
A1AKO C4  N5   sing N N 20  
A1AKO N5  N6   sing N N 21  
A1AKO N5  C22  sing N N 22  
A1AKO N6  C7   doub N N 23  
A1AKO C22 C15  sing N N 24  
A1AKO C7  C15  sing N N 25  
A1AKO C7  C8   sing N N 26  
A1AKO C14 C8   doub Y N 27  
A1AKO C14 C13  sing Y N 28  
A1AKO C15 C16  sing N N 29  
A1AKO C8  C9   sing Y N 30  
A1AKO C13 C11  doub Y N 31  
A1AKO C16 C17  doub Y N 32  
A1AKO C16 C21  sing Y N 33  
A1AKO C9  C10  doub Y N 34  
A1AKO C17 C18  sing Y N 35  
A1AKO C11 C10  sing Y N 36  
A1AKO C11 CL1  sing N N 37  
A1AKO C21 C20  doub Y N 38  
A1AKO C18 C19  doub Y N 39  
A1AKO C20 C19  sing Y N 40  
A1AKO N3  H1   sing N N 41  
A1AKO C10 H3   sing N N 42  
A1AKO C13 H4   sing N N 43  
A1AKO C15 H5   sing N N 44  
A1AKO C17 H6   sing N N 45  
A1AKO C20 H7   sing N N 46  
A1AKO C21 H8   sing N N 47  
A1AKO C22 H9   sing N N 48  
A1AKO C22 H10  sing N N 49  
A1AKO C26 H11  sing N N 50  
A1AKO C26 H12  sing N N 51  
A1AKO C26 H13  sing N N 52  
A1AKO C28 H14  sing N N 53  
A1AKO C14 H15  sing N N 54  
A1AKO C18 H16  sing N N 55  
A1AKO C19 H17  sing N N 56  
A1AKO C29 H18  sing N N 57  
A1AKO C35 H19  sing N N 58  
A1AKO C36 H20  sing N N 59  
A1AKO C9  H21  sing N N 60  
A1AKO N25 H22  sing N N 61  
ALA   N   CA   sing N N 62  
ALA   N   H    sing N N 63  
ALA   N   H2   sing N N 64  
ALA   CA  C    sing N N 65  
ALA   CA  CB   sing N N 66  
ALA   CA  HA   sing N N 67  
ALA   C   O    doub N N 68  
ALA   C   OXT  sing N N 69  
ALA   CB  HB1  sing N N 70  
ALA   CB  HB2  sing N N 71  
ALA   CB  HB3  sing N N 72  
ALA   OXT HXT  sing N N 73  
ARG   N   CA   sing N N 74  
ARG   N   H    sing N N 75  
ARG   N   H2   sing N N 76  
ARG   CA  C    sing N N 77  
ARG   CA  CB   sing N N 78  
ARG   CA  HA   sing N N 79  
ARG   C   O    doub N N 80  
ARG   C   OXT  sing N N 81  
ARG   CB  CG   sing N N 82  
ARG   CB  HB2  sing N N 83  
ARG   CB  HB3  sing N N 84  
ARG   CG  CD   sing N N 85  
ARG   CG  HG2  sing N N 86  
ARG   CG  HG3  sing N N 87  
ARG   CD  NE   sing N N 88  
ARG   CD  HD2  sing N N 89  
ARG   CD  HD3  sing N N 90  
ARG   NE  CZ   sing N N 91  
ARG   NE  HE   sing N N 92  
ARG   CZ  NH1  sing N N 93  
ARG   CZ  NH2  doub N N 94  
ARG   NH1 HH11 sing N N 95  
ARG   NH1 HH12 sing N N 96  
ARG   NH2 HH21 sing N N 97  
ARG   NH2 HH22 sing N N 98  
ARG   OXT HXT  sing N N 99  
ASN   N   CA   sing N N 100 
ASN   N   H    sing N N 101 
ASN   N   H2   sing N N 102 
ASN   CA  C    sing N N 103 
ASN   CA  CB   sing N N 104 
ASN   CA  HA   sing N N 105 
ASN   C   O    doub N N 106 
ASN   C   OXT  sing N N 107 
ASN   CB  CG   sing N N 108 
ASN   CB  HB2  sing N N 109 
ASN   CB  HB3  sing N N 110 
ASN   CG  OD1  doub N N 111 
ASN   CG  ND2  sing N N 112 
ASN   ND2 HD21 sing N N 113 
ASN   ND2 HD22 sing N N 114 
ASN   OXT HXT  sing N N 115 
ASP   N   CA   sing N N 116 
ASP   N   H    sing N N 117 
ASP   N   H2   sing N N 118 
ASP   CA  C    sing N N 119 
ASP   CA  CB   sing N N 120 
ASP   CA  HA   sing N N 121 
ASP   C   O    doub N N 122 
ASP   C   OXT  sing N N 123 
ASP   CB  CG   sing N N 124 
ASP   CB  HB2  sing N N 125 
ASP   CB  HB3  sing N N 126 
ASP   CG  OD1  doub N N 127 
ASP   CG  OD2  sing N N 128 
ASP   OD2 HD2  sing N N 129 
ASP   OXT HXT  sing N N 130 
CYS   N   CA   sing N N 131 
CYS   N   H    sing N N 132 
CYS   N   H2   sing N N 133 
CYS   CA  C    sing N N 134 
CYS   CA  CB   sing N N 135 
CYS   CA  HA   sing N N 136 
CYS   C   O    doub N N 137 
CYS   C   OXT  sing N N 138 
CYS   CB  SG   sing N N 139 
CYS   CB  HB2  sing N N 140 
CYS   CB  HB3  sing N N 141 
CYS   SG  HG   sing N N 142 
CYS   OXT HXT  sing N N 143 
GLN   N   CA   sing N N 144 
GLN   N   H    sing N N 145 
GLN   N   H2   sing N N 146 
GLN   CA  C    sing N N 147 
GLN   CA  CB   sing N N 148 
GLN   CA  HA   sing N N 149 
GLN   C   O    doub N N 150 
GLN   C   OXT  sing N N 151 
GLN   CB  CG   sing N N 152 
GLN   CB  HB2  sing N N 153 
GLN   CB  HB3  sing N N 154 
GLN   CG  CD   sing N N 155 
GLN   CG  HG2  sing N N 156 
GLN   CG  HG3  sing N N 157 
GLN   CD  OE1  doub N N 158 
GLN   CD  NE2  sing N N 159 
GLN   NE2 HE21 sing N N 160 
GLN   NE2 HE22 sing N N 161 
GLN   OXT HXT  sing N N 162 
GLU   N   CA   sing N N 163 
GLU   N   H    sing N N 164 
GLU   N   H2   sing N N 165 
GLU   CA  C    sing N N 166 
GLU   CA  CB   sing N N 167 
GLU   CA  HA   sing N N 168 
GLU   C   O    doub N N 169 
GLU   C   OXT  sing N N 170 
GLU   CB  CG   sing N N 171 
GLU   CB  HB2  sing N N 172 
GLU   CB  HB3  sing N N 173 
GLU   CG  CD   sing N N 174 
GLU   CG  HG2  sing N N 175 
GLU   CG  HG3  sing N N 176 
GLU   CD  OE1  doub N N 177 
GLU   CD  OE2  sing N N 178 
GLU   OE2 HE2  sing N N 179 
GLU   OXT HXT  sing N N 180 
GLY   N   CA   sing N N 181 
GLY   N   H    sing N N 182 
GLY   N   H2   sing N N 183 
GLY   CA  C    sing N N 184 
GLY   CA  HA2  sing N N 185 
GLY   CA  HA3  sing N N 186 
GLY   C   O    doub N N 187 
GLY   C   OXT  sing N N 188 
GLY   OXT HXT  sing N N 189 
HIS   N   CA   sing N N 190 
HIS   N   H    sing N N 191 
HIS   N   H2   sing N N 192 
HIS   CA  C    sing N N 193 
HIS   CA  CB   sing N N 194 
HIS   CA  HA   sing N N 195 
HIS   C   O    doub N N 196 
HIS   C   OXT  sing N N 197 
HIS   CB  CG   sing N N 198 
HIS   CB  HB2  sing N N 199 
HIS   CB  HB3  sing N N 200 
HIS   CG  ND1  sing Y N 201 
HIS   CG  CD2  doub Y N 202 
HIS   ND1 CE1  doub Y N 203 
HIS   ND1 HD1  sing N N 204 
HIS   CD2 NE2  sing Y N 205 
HIS   CD2 HD2  sing N N 206 
HIS   CE1 NE2  sing Y N 207 
HIS   CE1 HE1  sing N N 208 
HIS   NE2 HE2  sing N N 209 
HIS   OXT HXT  sing N N 210 
ILE   N   CA   sing N N 211 
ILE   N   H    sing N N 212 
ILE   N   H2   sing N N 213 
ILE   CA  C    sing N N 214 
ILE   CA  CB   sing N N 215 
ILE   CA  HA   sing N N 216 
ILE   C   O    doub N N 217 
ILE   C   OXT  sing N N 218 
ILE   CB  CG1  sing N N 219 
ILE   CB  CG2  sing N N 220 
ILE   CB  HB   sing N N 221 
ILE   CG1 CD1  sing N N 222 
ILE   CG1 HG12 sing N N 223 
ILE   CG1 HG13 sing N N 224 
ILE   CG2 HG21 sing N N 225 
ILE   CG2 HG22 sing N N 226 
ILE   CG2 HG23 sing N N 227 
ILE   CD1 HD11 sing N N 228 
ILE   CD1 HD12 sing N N 229 
ILE   CD1 HD13 sing N N 230 
ILE   OXT HXT  sing N N 231 
LEU   N   CA   sing N N 232 
LEU   N   H    sing N N 233 
LEU   N   H2   sing N N 234 
LEU   CA  C    sing N N 235 
LEU   CA  CB   sing N N 236 
LEU   CA  HA   sing N N 237 
LEU   C   O    doub N N 238 
LEU   C   OXT  sing N N 239 
LEU   CB  CG   sing N N 240 
LEU   CB  HB2  sing N N 241 
LEU   CB  HB3  sing N N 242 
LEU   CG  CD1  sing N N 243 
LEU   CG  CD2  sing N N 244 
LEU   CG  HG   sing N N 245 
LEU   CD1 HD11 sing N N 246 
LEU   CD1 HD12 sing N N 247 
LEU   CD1 HD13 sing N N 248 
LEU   CD2 HD21 sing N N 249 
LEU   CD2 HD22 sing N N 250 
LEU   CD2 HD23 sing N N 251 
LEU   OXT HXT  sing N N 252 
LYS   N   CA   sing N N 253 
LYS   N   H    sing N N 254 
LYS   N   H2   sing N N 255 
LYS   CA  C    sing N N 256 
LYS   CA  CB   sing N N 257 
LYS   CA  HA   sing N N 258 
LYS   C   O    doub N N 259 
LYS   C   OXT  sing N N 260 
LYS   CB  CG   sing N N 261 
LYS   CB  HB2  sing N N 262 
LYS   CB  HB3  sing N N 263 
LYS   CG  CD   sing N N 264 
LYS   CG  HG2  sing N N 265 
LYS   CG  HG3  sing N N 266 
LYS   CD  CE   sing N N 267 
LYS   CD  HD2  sing N N 268 
LYS   CD  HD3  sing N N 269 
LYS   CE  NZ   sing N N 270 
LYS   CE  HE2  sing N N 271 
LYS   CE  HE3  sing N N 272 
LYS   NZ  HZ1  sing N N 273 
LYS   NZ  HZ2  sing N N 274 
LYS   NZ  HZ3  sing N N 275 
LYS   OXT HXT  sing N N 276 
MET   N   CA   sing N N 277 
MET   N   H    sing N N 278 
MET   N   H2   sing N N 279 
MET   CA  C    sing N N 280 
MET   CA  CB   sing N N 281 
MET   CA  HA   sing N N 282 
MET   C   O    doub N N 283 
MET   C   OXT  sing N N 284 
MET   CB  CG   sing N N 285 
MET   CB  HB2  sing N N 286 
MET   CB  HB3  sing N N 287 
MET   CG  SD   sing N N 288 
MET   CG  HG2  sing N N 289 
MET   CG  HG3  sing N N 290 
MET   SD  CE   sing N N 291 
MET   CE  HE1  sing N N 292 
MET   CE  HE2  sing N N 293 
MET   CE  HE3  sing N N 294 
MET   OXT HXT  sing N N 295 
PHE   N   CA   sing N N 296 
PHE   N   H    sing N N 297 
PHE   N   H2   sing N N 298 
PHE   CA  C    sing N N 299 
PHE   CA  CB   sing N N 300 
PHE   CA  HA   sing N N 301 
PHE   C   O    doub N N 302 
PHE   C   OXT  sing N N 303 
PHE   CB  CG   sing N N 304 
PHE   CB  HB2  sing N N 305 
PHE   CB  HB3  sing N N 306 
PHE   CG  CD1  doub Y N 307 
PHE   CG  CD2  sing Y N 308 
PHE   CD1 CE1  sing Y N 309 
PHE   CD1 HD1  sing N N 310 
PHE   CD2 CE2  doub Y N 311 
PHE   CD2 HD2  sing N N 312 
PHE   CE1 CZ   doub Y N 313 
PHE   CE1 HE1  sing N N 314 
PHE   CE2 CZ   sing Y N 315 
PHE   CE2 HE2  sing N N 316 
PHE   CZ  HZ   sing N N 317 
PHE   OXT HXT  sing N N 318 
PRO   N   CA   sing N N 319 
PRO   N   CD   sing N N 320 
PRO   N   H    sing N N 321 
PRO   CA  C    sing N N 322 
PRO   CA  CB   sing N N 323 
PRO   CA  HA   sing N N 324 
PRO   C   O    doub N N 325 
PRO   C   OXT  sing N N 326 
PRO   CB  CG   sing N N 327 
PRO   CB  HB2  sing N N 328 
PRO   CB  HB3  sing N N 329 
PRO   CG  CD   sing N N 330 
PRO   CG  HG2  sing N N 331 
PRO   CG  HG3  sing N N 332 
PRO   CD  HD2  sing N N 333 
PRO   CD  HD3  sing N N 334 
PRO   OXT HXT  sing N N 335 
SER   N   CA   sing N N 336 
SER   N   H    sing N N 337 
SER   N   H2   sing N N 338 
SER   CA  C    sing N N 339 
SER   CA  CB   sing N N 340 
SER   CA  HA   sing N N 341 
SER   C   O    doub N N 342 
SER   C   OXT  sing N N 343 
SER   CB  OG   sing N N 344 
SER   CB  HB2  sing N N 345 
SER   CB  HB3  sing N N 346 
SER   OG  HG   sing N N 347 
SER   OXT HXT  sing N N 348 
THR   N   CA   sing N N 349 
THR   N   H    sing N N 350 
THR   N   H2   sing N N 351 
THR   CA  C    sing N N 352 
THR   CA  CB   sing N N 353 
THR   CA  HA   sing N N 354 
THR   C   O    doub N N 355 
THR   C   OXT  sing N N 356 
THR   CB  OG1  sing N N 357 
THR   CB  CG2  sing N N 358 
THR   CB  HB   sing N N 359 
THR   OG1 HG1  sing N N 360 
THR   CG2 HG21 sing N N 361 
THR   CG2 HG22 sing N N 362 
THR   CG2 HG23 sing N N 363 
THR   OXT HXT  sing N N 364 
TRP   N   CA   sing N N 365 
TRP   N   H    sing N N 366 
TRP   N   H2   sing N N 367 
TRP   CA  C    sing N N 368 
TRP   CA  CB   sing N N 369 
TRP   CA  HA   sing N N 370 
TRP   C   O    doub N N 371 
TRP   C   OXT  sing N N 372 
TRP   CB  CG   sing N N 373 
TRP   CB  HB2  sing N N 374 
TRP   CB  HB3  sing N N 375 
TRP   CG  CD1  doub Y N 376 
TRP   CG  CD2  sing Y N 377 
TRP   CD1 NE1  sing Y N 378 
TRP   CD1 HD1  sing N N 379 
TRP   CD2 CE2  doub Y N 380 
TRP   CD2 CE3  sing Y N 381 
TRP   NE1 CE2  sing Y N 382 
TRP   NE1 HE1  sing N N 383 
TRP   CE2 CZ2  sing Y N 384 
TRP   CE3 CZ3  doub Y N 385 
TRP   CE3 HE3  sing N N 386 
TRP   CZ2 CH2  doub Y N 387 
TRP   CZ2 HZ2  sing N N 388 
TRP   CZ3 CH2  sing Y N 389 
TRP   CZ3 HZ3  sing N N 390 
TRP   CH2 HH2  sing N N 391 
TRP   OXT HXT  sing N N 392 
TYR   N   CA   sing N N 393 
TYR   N   H    sing N N 394 
TYR   N   H2   sing N N 395 
TYR   CA  C    sing N N 396 
TYR   CA  CB   sing N N 397 
TYR   CA  HA   sing N N 398 
TYR   C   O    doub N N 399 
TYR   C   OXT  sing N N 400 
TYR   CB  CG   sing N N 401 
TYR   CB  HB2  sing N N 402 
TYR   CB  HB3  sing N N 403 
TYR   CG  CD1  doub Y N 404 
TYR   CG  CD2  sing Y N 405 
TYR   CD1 CE1  sing Y N 406 
TYR   CD1 HD1  sing N N 407 
TYR   CD2 CE2  doub Y N 408 
TYR   CD2 HD2  sing N N 409 
TYR   CE1 CZ   doub Y N 410 
TYR   CE1 HE1  sing N N 411 
TYR   CE2 CZ   sing Y N 412 
TYR   CE2 HE2  sing N N 413 
TYR   CZ  OH   sing N N 414 
TYR   OH  HH   sing N N 415 
TYR   OXT HXT  sing N N 416 
VAL   N   CA   sing N N 417 
VAL   N   H    sing N N 418 
VAL   N   H2   sing N N 419 
VAL   CA  C    sing N N 420 
VAL   CA  CB   sing N N 421 
VAL   CA  HA   sing N N 422 
VAL   C   O    doub N N 423 
VAL   C   OXT  sing N N 424 
VAL   CB  CG1  sing N N 425 
VAL   CB  CG2  sing N N 426 
VAL   CB  HB   sing N N 427 
VAL   CG1 HG11 sing N N 428 
VAL   CG1 HG12 sing N N 429 
VAL   CG1 HG13 sing N N 430 
VAL   CG2 HG21 sing N N 431 
VAL   CG2 HG22 sing N N 432 
VAL   CG2 HG23 sing N N 433 
VAL   OXT HXT  sing N N 434 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-04-03 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B9Z 
_em_admin.last_update        2025-01-01 
_em_admin.map_release_date   2024-11-20 
_em_admin.title              'Structural mechanism of CB1R binding to peripheral and biased inverse agonists' 
# 
loop_
_em_buffer_component.buffer_id 
_em_buffer_component.concentration 
_em_buffer_component.concentration_units 
_em_buffer_component.formula 
_em_buffer_component.id 
_em_buffer_component.name 
1 150   mM NaCl 1 'Sodium Chloride'                      
1 20    mM ?    2 HEPES                                  
1 0.005 %  ?    3 'Laurylmaltose neopentylglycol (LMNG)' 
1 0.001 %  ?    4 CHS                                    
1 0.001 %  ?    5 'Sodium Cholate'                       
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_molwt.entity_assembly_id   1 
_em_entity_assembly_molwt.experimental_flag    NO 
_em_entity_assembly_molwt.id                   1 
_em_entity_assembly_molwt.units                ? 
_em_entity_assembly_molwt.value                ? 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          9606 
_em_entity_assembly_naturalsource.organism             'Homo sapiens' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          7108 
_em_entity_assembly_recombinant.organism             'Spodoptera frugiperda' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         1.0 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
_em_particle_selection.details                  ? 
_em_particle_selection.id                       1 
_em_particle_selection.image_processing_id      1 
_em_particle_selection.method                   ? 
_em_particle_selection.num_particles_selected   1470000 
_em_particle_selection.reference_model          ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?        ?   
'IMAGE ACQUISITION'             ? 2  ? ? 1 SerialEM ?   
MASKING                         ? 3  ? ? ? ?        ?   
'CTF CORRECTION'                ? 4  1 ? ? ?        ?   
'LAYERLINE INDEXING'            ? 5  ? ? ? ?        ?   
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?        ?   
'MODEL FITTING'                 ? 7  ? 1 ? PHENIX   ?   
OTHER                           ? 8  ? ? ? ?        ?   
'MODEL REFINEMENT'              ? 9  ? 1 ? Coot     ?   
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? RELION   3.1 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?        ?   
CLASSIFICATION                  ? 12 1 ? ? ?        ?   
RECONSTRUCTION                  ? 13 1 ? ? ?        ?   
'VOLUME SELECTION'              ? 14 1 1 1 ?        ?   
'SERIES ALIGNMENT'              ? 15 1 1 1 ?        ?   
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?        ?   
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?        ?   
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?        ?   
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?        ?   
# 
_em_specimen.concentration           2.75 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           GM116387 
_pdbx_audit_support.ordinal                1 
# 
_atom_sites.entry_id                    9B9Z 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C  
CL 
F  
N  
O  
S  
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N  N   . VAL   A 1 2   ? 128.931 149.623 176.191 1.00 79.26  ? 2    VAL   N N   1 
ATOM   2    C  CA  . VAL   A 1 2   ? 129.698 148.446 176.576 1.00 79.26  ? 2    VAL   N CA  1 
ATOM   3    C  C   . VAL   A 1 2   ? 128.893 147.596 177.547 1.00 79.26  ? 2    VAL   N C   1 
ATOM   4    O  O   . VAL   A 1 2   ? 127.890 148.047 178.097 1.00 79.26  ? 2    VAL   N O   1 
ATOM   5    C  CB  . VAL   A 1 2   ? 131.054 148.838 177.190 1.00 79.26  ? 2    VAL   N CB  1 
ATOM   6    C  CG1 . VAL   A 1 2   ? 131.815 149.748 176.247 1.00 79.26  ? 2    VAL   N CG1 1 
ATOM   7    C  CG2 . VAL   A 1 2   ? 130.855 149.510 178.534 1.00 79.26  ? 2    VAL   N CG2 1 
ATOM   8    N  N   . GLN   A 1 3   ? 129.333 146.358 177.752 1.00 81.47  ? 3    GLN   N N   1 
ATOM   9    C  CA  . GLN   A 1 3   ? 128.662 145.447 178.666 1.00 81.47  ? 3    GLN   N CA  1 
ATOM   10   C  C   . GLN   A 1 3   ? 129.700 144.706 179.493 1.00 81.47  ? 3    GLN   N C   1 
ATOM   11   O  O   . GLN   A 1 3   ? 130.745 144.302 178.976 1.00 81.47  ? 3    GLN   N O   1 
ATOM   12   C  CB  . GLN   A 1 3   ? 127.771 144.446 177.911 1.00 81.47  ? 3    GLN   N CB  1 
ATOM   13   C  CG  . GLN   A 1 3   ? 126.920 143.438 178.741 1.00 81.47  ? 3    GLN   N CG  1 
ATOM   14   C  CD  . GLN   A 1 3   ? 125.988 144.030 179.819 1.00 81.47  ? 3    GLN   N CD  1 
ATOM   15   O  OE1 . GLN   A 1 3   ? 126.377 144.839 180.664 1.00 81.47  ? 3    GLN   N OE1 1 
ATOM   16   N  NE2 . GLN   A 1 3   ? 124.731 143.606 179.775 1.00 81.47  ? 3    GLN   N NE2 1 
ATOM   17   N  N   . LEU   A 1 4   ? 129.404 144.530 180.777 1.00 77.43  ? 4    LEU   N N   1 
ATOM   18   C  CA  . LEU   A 1 4   ? 130.312 143.892 181.720 1.00 77.43  ? 4    LEU   N CA  1 
ATOM   19   C  C   . LEU   A 1 4   ? 129.595 142.741 182.408 1.00 77.43  ? 4    LEU   N C   1 
ATOM   20   O  O   . LEU   A 1 4   ? 128.433 142.876 182.806 1.00 77.43  ? 4    LEU   N O   1 
ATOM   21   C  CB  . LEU   A 1 4   ? 130.823 144.891 182.760 1.00 77.43  ? 4    LEU   N CB  1 
ATOM   22   C  CG  . LEU   A 1 4   ? 131.943 145.844 182.338 1.00 77.43  ? 4    LEU   N CG  1 
ATOM   23   C  CD1 . LEU   A 1 4   ? 131.398 147.056 181.605 1.00 77.43  ? 4    LEU   N CD1 1 
ATOM   24   C  CD2 . LEU   A 1 4   ? 132.748 146.279 183.541 1.00 77.43  ? 4    LEU   N CD2 1 
ATOM   25   N  N   . GLN   A 1 5   ? 130.289 141.616 182.549 1.00 83.08  ? 5    GLN   N N   1 
ATOM   26   C  CA  . GLN   A 1 5   ? 129.745 140.423 183.181 1.00 83.08  ? 5    GLN   N CA  1 
ATOM   27   C  C   . GLN   A 1 5   ? 130.700 139.944 184.263 1.00 83.08  ? 5    GLN   N C   1 
ATOM   28   O  O   . GLN   A 1 5   ? 131.905 139.818 184.019 1.00 83.08  ? 5    GLN   N O   1 
ATOM   29   C  CB  . GLN   A 1 5   ? 129.509 139.315 182.154 1.00 83.08  ? 5    GLN   N CB  1 
ATOM   30   C  CG  . GLN   A 1 5   ? 128.266 139.518 181.304 1.00 83.08  ? 5    GLN   N CG  1 
ATOM   31   C  CD  . GLN   A 1 5   ? 126.987 139.427 182.112 1.00 83.08  ? 5    GLN   N CD  1 
ATOM   32   O  OE1 . GLN   A 1 5   ? 126.400 140.444 182.482 1.00 83.08  ? 5    GLN   N OE1 1 
ATOM   33   N  NE2 . GLN   A 1 5   ? 126.549 138.205 182.391 1.00 83.08  ? 5    GLN   N NE2 1 
ATOM   34   N  N   . GLU   A 1 6   ? 130.162 139.667 185.447 1.00 82.28  ? 6    GLU   N N   1 
ATOM   35   C  CA  . GLU   A 1 6   ? 130.953 139.258 186.597 1.00 82.28  ? 6    GLU   N CA  1 
ATOM   36   C  C   . GLU   A 1 6   ? 130.656 137.811 186.970 1.00 82.28  ? 6    GLU   N C   1 
ATOM   37   O  O   . GLU   A 1 6   ? 129.571 137.289 186.701 1.00 82.28  ? 6    GLU   N O   1 
ATOM   38   C  CB  . GLU   A 1 6   ? 130.681 140.159 187.803 1.00 82.28  ? 6    GLU   N CB  1 
ATOM   39   C  CG  . GLU   A 1 6   ? 130.409 141.607 187.461 1.00 82.28  ? 6    GLU   N CG  1 
ATOM   40   C  CD  . GLU   A 1 6   ? 130.438 142.499 188.684 1.00 82.28  ? 6    GLU   N CD  1 
ATOM   41   O  OE1 . GLU   A 1 6   ? 130.689 141.979 189.790 1.00 82.28  ? 6    GLU   N OE1 1 
ATOM   42   O  OE2 . GLU   A 1 6   ? 130.211 143.718 188.543 1.00 82.28  ? 6    GLU   N OE2 1 
ATOM   43   N  N   . SER   A 1 7   ? 131.642 137.169 187.593 1.00 86.52  ? 7    SER   N N   1 
ATOM   44   C  CA  . SER   A 1 7   ? 131.500 135.800 188.065 1.00 86.52  ? 7    SER   N CA  1 
ATOM   45   C  C   . SER   A 1 7   ? 132.433 135.579 189.248 1.00 86.52  ? 7    SER   N C   1 
ATOM   46   O  O   . SER   A 1 7   ? 133.507 136.182 189.333 1.00 86.52  ? 7    SER   N O   1 
ATOM   47   C  CB  . SER   A 1 7   ? 131.801 134.785 186.956 1.00 86.52  ? 7    SER   N CB  1 
ATOM   48   O  OG  . SER   A 1 7   ? 130.862 134.887 185.899 1.00 86.52  ? 7    SER   N OG  1 
ATOM   49   N  N   . GLY   A 1 8   ? 132.011 134.707 190.161 1.00 89.02  ? 8    GLY   N N   1 
ATOM   50   C  CA  . GLY   A 1 8   ? 132.812 134.351 191.321 1.00 89.02  ? 8    GLY   N CA  1 
ATOM   51   C  C   . GLY   A 1 8   ? 132.168 134.620 192.668 1.00 89.02  ? 8    GLY   N C   1 
ATOM   52   O  O   . GLY   A 1 8   ? 132.836 134.434 193.694 1.00 89.02  ? 8    GLY   N O   1 
ATOM   53   N  N   . GLY   A 1 9   ? 130.908 135.049 192.736 1.00 93.43  ? 9    GLY   N N   1 
ATOM   54   C  CA  . GLY   A 1 9   ? 130.288 135.326 194.015 1.00 93.43  ? 9    GLY   N CA  1 
ATOM   55   C  C   . GLY   A 1 9   ? 129.840 134.074 194.752 1.00 93.43  ? 9    GLY   N C   1 
ATOM   56   O  O   . GLY   A 1 9   ? 129.782 132.975 194.202 1.00 93.43  ? 9    GLY   N O   1 
ATOM   57   N  N   . GLY   A 1 10  ? 129.518 134.255 196.025 1.00 96.41  ? 10   GLY   N N   1 
ATOM   58   C  CA  . GLY   A 1 10  ? 129.011 133.169 196.839 1.00 96.41  ? 10   GLY   N CA  1 
ATOM   59   C  C   . GLY   A 1 10  ? 129.505 133.282 198.269 1.00 96.41  ? 10   GLY   N C   1 
ATOM   60   O  O   . GLY   A 1 10  ? 129.824 134.367 198.749 1.00 96.41  ? 10   GLY   N O   1 
ATOM   61   N  N   . LEU   A 1 11  ? 129.550 132.130 198.934 1.00 101.50 ? 11   LEU   N N   1 
ATOM   62   C  CA  . LEU   A 1 11  ? 129.970 132.026 200.324 1.00 101.50 ? 11   LEU   N CA  1 
ATOM   63   C  C   . LEU   A 1 11  ? 131.345 131.375 200.382 1.00 101.50 ? 11   LEU   N C   1 
ATOM   64   O  O   . LEU   A 1 11  ? 131.620 130.409 199.663 1.00 101.50 ? 11   LEU   N O   1 
ATOM   65   C  CB  . LEU   A 1 11  ? 128.937 131.232 201.146 1.00 101.50 ? 11   LEU   N CB  1 
ATOM   66   C  CG  . LEU   A 1 11  ? 129.013 130.942 202.658 1.00 101.50 ? 11   LEU   N CG  1 
ATOM   67   C  CD1 . LEU   A 1 11  ? 127.633 130.527 203.132 1.00 101.50 ? 11   LEU   N CD1 1 
ATOM   68   C  CD2 . LEU   A 1 11  ? 130.010 129.855 203.068 1.00 101.50 ? 11   LEU   N CD2 1 
ATOM   69   N  N   . VAL   A 1 12  ? 132.207 131.919 201.236 1.00 104.10 ? 12   VAL   N N   1 
ATOM   70   C  CA  . VAL   A 1 12  ? 133.582 131.456 201.393 1.00 104.10 ? 12   VAL   N CA  1 
ATOM   71   C  C   . VAL   A 1 12  ? 133.861 131.265 202.879 1.00 104.10 ? 12   VAL   N C   1 
ATOM   72   O  O   . VAL   A 1 12  ? 133.527 132.132 203.695 1.00 104.10 ? 12   VAL   N O   1 
ATOM   73   C  CB  . VAL   A 1 12  ? 134.588 132.446 200.768 1.00 104.10 ? 12   VAL   N CB  1 
ATOM   74   C  CG1 . VAL   A 1 12  ? 136.021 132.048 201.076 1.00 104.10 ? 12   VAL   N CG1 1 
ATOM   75   C  CG2 . VAL   A 1 12  ? 134.393 132.526 199.266 1.00 104.10 ? 12   VAL   N CG2 1 
ATOM   76   N  N   . GLN   A 1 13  ? 134.453 130.125 203.228 1.00 110.01 ? 13   GLN   N N   1 
ATOM   77   C  CA  . GLN   A 1 13  ? 134.897 129.889 204.594 1.00 110.01 ? 13   GLN   N CA  1 
ATOM   78   C  C   . GLN   A 1 13  ? 136.056 130.823 204.935 1.00 110.01 ? 13   GLN   N C   1 
ATOM   79   O  O   . GLN   A 1 13  ? 136.895 131.138 204.087 1.00 110.01 ? 13   GLN   N O   1 
ATOM   80   C  CB  . GLN   A 1 13  ? 135.311 128.424 204.761 1.00 110.01 ? 13   GLN   N CB  1 
ATOM   81   C  CG  . GLN   A 1 13  ? 135.719 128.020 206.166 1.00 110.01 ? 13   GLN   N CG  1 
ATOM   82   C  CD  . GLN   A 1 13  ? 134.558 128.077 207.136 1.00 110.01 ? 13   GLN   N CD  1 
ATOM   83   O  OE1 . GLN   A 1 13  ? 133.440 127.681 206.807 1.00 110.01 ? 13   GLN   N OE1 1 
ATOM   84   N  NE2 . GLN   A 1 13  ? 134.817 128.571 208.341 1.00 110.01 ? 13   GLN   N NE2 1 
ATOM   85   N  N   . ALA   A 1 14  ? 136.087 131.276 206.190 1.00 107.66 ? 14   ALA   N N   1 
ATOM   86   C  CA  . ALA   A 1 14  ? 137.063 132.272 206.617 1.00 107.66 ? 14   ALA   N CA  1 
ATOM   87   C  C   . ALA   A 1 14  ? 138.485 131.728 206.546 1.00 107.66 ? 14   ALA   N C   1 
ATOM   88   O  O   . ALA   A 1 14  ? 138.751 130.581 206.911 1.00 107.66 ? 14   ALA   N O   1 
ATOM   89   C  CB  . ALA   A 1 14  ? 136.756 132.738 208.039 1.00 107.66 ? 14   ALA   N CB  1 
ATOM   90   N  N   . GLY   A 1 15  ? 139.400 132.572 206.076 1.00 102.25 ? 15   GLY   N N   1 
ATOM   91   C  CA  . GLY   A 1 15  ? 140.769 132.176 205.834 1.00 102.25 ? 15   GLY   N CA  1 
ATOM   92   C  C   . GLY   A 1 15  ? 141.038 131.632 204.449 1.00 102.25 ? 15   GLY   N C   1 
ATOM   93   O  O   . GLY   A 1 15  ? 142.201 131.369 204.121 1.00 102.25 ? 15   GLY   N O   1 
ATOM   94   N  N   . GLY   A 1 16  ? 140.009 131.464 203.626 1.00 97.72  ? 16   GLY   N N   1 
ATOM   95   C  CA  . GLY   A 1 16  ? 140.170 130.913 202.300 1.00 97.72  ? 16   GLY   N CA  1 
ATOM   96   C  C   . GLY   A 1 16  ? 140.594 131.957 201.284 1.00 97.72  ? 16   GLY   N C   1 
ATOM   97   O  O   . GLY   A 1 16  ? 140.993 133.076 201.611 1.00 97.72  ? 16   GLY   N O   1 
ATOM   98   N  N   . SER   A 1 17  ? 140.507 131.564 200.017 1.00 92.17  ? 17   SER   N N   1 
ATOM   99   C  CA  . SER   A 1 17  ? 140.868 132.420 198.899 1.00 92.17  ? 17   SER   N CA  1 
ATOM   100  C  C   . SER   A 1 17  ? 139.791 132.335 197.828 1.00 92.17  ? 17   SER   N C   1 
ATOM   101  O  O   . SER   A 1 17  ? 139.077 131.336 197.722 1.00 92.17  ? 17   SER   N O   1 
ATOM   102  C  CB  . SER   A 1 17  ? 142.227 132.024 198.311 1.00 92.17  ? 17   SER   N CB  1 
ATOM   103  O  OG  . SER   A 1 17  ? 142.758 133.068 197.515 1.00 92.17  ? 17   SER   N OG  1 
ATOM   104  N  N   . LEU   A 1 18  ? 139.682 133.395 197.032 1.00 86.83  ? 18   LEU   N N   1 
ATOM   105  C  CA  . LEU   A 1 18  ? 138.670 133.443 195.987 1.00 86.83  ? 18   LEU   N CA  1 
ATOM   106  C  C   . LEU   A 1 18  ? 139.193 134.212 194.779 1.00 86.83  ? 18   LEU   N C   1 
ATOM   107  O  O   . LEU   A 1 18  ? 140.052 135.097 194.897 1.00 86.83  ? 18   LEU   N O   1 
ATOM   108  C  CB  . LEU   A 1 18  ? 137.362 134.064 196.505 1.00 86.83  ? 18   LEU   N CB  1 
ATOM   109  C  CG  . LEU   A 1 18  ? 136.106 134.001 195.625 1.00 86.83  ? 18   LEU   N CG  1 
ATOM   110  C  CD1 . LEU   A 1 18  ? 135.792 132.571 195.229 1.00 86.83  ? 18   LEU   N CD1 1 
ATOM   111  C  CD2 . LEU   A 1 18  ? 134.917 134.652 196.302 1.00 86.83  ? 18   LEU   N CD2 1 
ATOM   112  N  N   . ARG   A 1 19  ? 138.668 133.831 193.614 1.00 83.21  ? 19   ARG   N N   1 
ATOM   113  C  CA  . ARG   A 1 19  ? 138.897 134.492 192.337 1.00 83.21  ? 19   ARG   N CA  1 
ATOM   114  C  C   . ARG   A 1 19  ? 137.593 135.114 191.857 1.00 83.21  ? 19   ARG   N C   1 
ATOM   115  O  O   . ARG   A 1 19  ? 136.568 134.430 191.780 1.00 83.21  ? 19   ARG   N O   1 
ATOM   116  C  CB  . ARG   A 1 19  ? 139.389 133.492 191.288 1.00 83.21  ? 19   ARG   N CB  1 
ATOM   117  C  CG  . ARG   A 1 19  ? 140.834 133.060 191.416 1.00 83.21  ? 19   ARG   N CG  1 
ATOM   118  C  CD  . ARG   A 1 19  ? 141.739 134.210 191.797 1.00 83.21  ? 19   ARG   N CD  1 
ATOM   119  N  NE  . ARG   A 1 19  ? 143.137 133.952 191.470 1.00 83.21  ? 19   ARG   N NE  1 
ATOM   120  C  CZ  . ARG   A 1 19  ? 143.644 133.933 190.244 1.00 83.21  ? 19   ARG   N CZ  1 
ATOM   121  N  NH1 . ARG   A 1 19  ? 142.909 134.221 189.182 1.00 83.21  ? 19   ARG   N NH1 1 
ATOM   122  N  NH2 . ARG   A 1 19  ? 144.930 133.635 190.080 1.00 83.21  ? 19   ARG   N NH2 1 
ATOM   123  N  N   . LEU   A 1 20  ? 137.633 136.401 191.528 1.00 82.52  ? 20   LEU   N N   1 
ATOM   124  C  CA  . LEU   A 1 20  ? 136.530 137.072 190.855 1.00 82.52  ? 20   LEU   N CA  1 
ATOM   125  C  C   . LEU   A 1 20  ? 136.963 137.464 189.452 1.00 82.52  ? 20   LEU   N C   1 
ATOM   126  O  O   . LEU   A 1 20  ? 138.095 137.907 189.246 1.00 82.52  ? 20   LEU   N O   1 
ATOM   127  C  CB  . LEU   A 1 20  ? 136.066 138.316 191.616 1.00 82.52  ? 20   LEU   N CB  1 
ATOM   128  C  CG  . LEU   A 1 20  ? 135.166 138.135 192.837 1.00 82.52  ? 20   LEU   N CG  1 
ATOM   129  C  CD1 . LEU   A 1 20  ? 135.345 139.291 193.793 1.00 82.52  ? 20   LEU   N CD1 1 
ATOM   130  C  CD2 . LEU   A 1 20  ? 133.716 138.023 192.407 1.00 82.52  ? 20   LEU   N CD2 1 
ATOM   131  N  N   . SER   A 1 21  ? 136.061 137.297 188.491 1.00 81.24  ? 21   SER   N N   1 
ATOM   132  C  CA  . SER   A 1 21  ? 136.339 137.593 187.095 1.00 81.24  ? 21   SER   N CA  1 
ATOM   133  C  C   . SER   A 1 21  ? 135.310 138.580 186.570 1.00 81.24  ? 21   SER   N C   1 
ATOM   134  O  O   . SER   A 1 21  ? 134.123 138.480 186.889 1.00 81.24  ? 21   SER   N O   1 
ATOM   135  C  CB  . SER   A 1 21  ? 136.320 136.318 186.247 1.00 81.24  ? 21   SER   N CB  1 
ATOM   136  O  OG  . SER   A 1 21  ? 136.558 136.605 184.881 1.00 81.24  ? 21   SER   N OG  1 
ATOM   137  N  N   . CYS   A 1 22  ? 135.772 139.539 185.772 1.00 79.94  ? 22   CYS   N N   1 
ATOM   138  C  CA  . CYS   A 1 22  ? 134.885 140.520 185.155 1.00 79.94  ? 22   CYS   N CA  1 
ATOM   139  C  C   . CYS   A 1 22  ? 135.331 140.748 183.723 1.00 79.94  ? 22   CYS   N C   1 
ATOM   140  O  O   . CYS   A 1 22  ? 136.471 141.154 183.487 1.00 79.94  ? 22   CYS   N O   1 
ATOM   141  C  CB  . CYS   A 1 22  ? 134.888 141.832 185.939 1.00 79.94  ? 22   CYS   N CB  1 
ATOM   142  S  SG  . CYS   A 1 22  ? 134.105 143.226 185.115 1.00 79.94  ? 22   CYS   N SG  1 
ATOM   143  N  N   . ALA   A 1 23  ? 134.435 140.497 182.775 1.00 79.65  ? 23   ALA   N N   1 
ATOM   144  C  CA  . ALA   A 1 23  ? 134.734 140.607 181.355 1.00 79.65  ? 23   ALA   N CA  1 
ATOM   145  C  C   . ALA   A 1 23  ? 133.941 141.750 180.738 1.00 79.65  ? 23   ALA   N C   1 
ATOM   146  O  O   . ALA   A 1 23  ? 132.760 141.935 181.046 1.00 79.65  ? 23   ALA   N O   1 
ATOM   147  C  CB  . ALA   A 1 23  ? 134.420 139.301 180.625 1.00 79.65  ? 23   ALA   N CB  1 
ATOM   148  N  N   . ALA   A 1 24  ? 134.595 142.507 179.860 1.00 77.27  ? 24   ALA   N N   1 
ATOM   149  C  CA  . ALA   A 1 24  ? 134.005 143.674 179.225 1.00 77.27  ? 24   ALA   N CA  1 
ATOM   150  C  C   . ALA   A 1 24  ? 133.973 143.495 177.714 1.00 77.27  ? 24   ALA   N C   1 
ATOM   151  O  O   . ALA   A 1 24  ? 134.854 142.860 177.129 1.00 77.27  ? 24   ALA   N O   1 
ATOM   152  C  CB  . ALA   A 1 24  ? 134.781 144.945 179.577 1.00 77.27  ? 24   ALA   N CB  1 
ATOM   153  N  N   . SER   A 1 25  ? 132.948 144.066 177.086 1.00 79.37  ? 25   SER   N N   1 
ATOM   154  C  CA  . SER   A 1 25  ? 132.753 143.971 175.639 1.00 79.37  ? 25   SER   N CA  1 
ATOM   155  C  C   . SER   A 1 25  ? 132.752 145.377 175.044 1.00 79.37  ? 25   SER   N C   1 
ATOM   156  O  O   . SER   A 1 25  ? 131.697 145.994 174.881 1.00 79.37  ? 25   SER   N O   1 
ATOM   157  C  CB  . SER   A 1 25  ? 131.461 143.227 175.312 1.00 79.37  ? 25   SER   N CB  1 
ATOM   158  O  OG  . SER   A 1 25  ? 131.470 141.922 175.862 1.00 79.37  ? 25   SER   N OG  1 
ATOM   159  N  N   . GLY   A 1 26  ? 133.942 145.876 174.708 1.00 79.84  ? 26   GLY   N N   1 
ATOM   160  C  CA  . GLY   A 1 26  ? 134.103 147.164 174.076 1.00 79.84  ? 26   GLY   N CA  1 
ATOM   161  C  C   . GLY   A 1 26  ? 134.530 147.042 172.621 1.00 79.84  ? 26   GLY   N C   1 
ATOM   162  O  O   . GLY   A 1 26  ? 134.768 145.958 172.095 1.00 79.84  ? 26   GLY   N O   1 
ATOM   163  N  N   . THR   A 1 27  ? 134.631 148.200 171.972 1.00 77.49  ? 27   THR   N N   1 
ATOM   164  C  CA  . THR   A 1 27  ? 134.966 148.242 170.554 1.00 77.49  ? 27   THR   N CA  1 
ATOM   165  C  C   . THR   A 1 27  ? 136.433 148.545 170.275 1.00 77.49  ? 27   THR   N C   1 
ATOM   166  O  O   . THR   A 1 27  ? 136.981 148.018 169.301 1.00 77.49  ? 27   THR   N O   1 
ATOM   167  C  CB  . THR   A 1 27  ? 134.076 149.262 169.822 1.00 77.49  ? 27   THR   N CB  1 
ATOM   168  O  OG1 . THR   A 1 27  ? 134.432 149.309 168.434 1.00 77.49  ? 27   THR   N OG1 1 
ATOM   169  C  CG2 . THR   A 1 27  ? 134.166 150.659 170.441 1.00 77.49  ? 27   THR   N CG2 1 
ATOM   170  N  N   . ILE   A 1 28  ? 137.086 149.368 171.092 1.00 70.79  ? 28   ILE   N N   1 
ATOM   171  C  CA  . ILE   A 1 28  ? 138.507 149.647 170.922 1.00 70.79  ? 28   ILE   N CA  1 
ATOM   172  C  C   . ILE   A 1 28  ? 139.188 149.609 172.287 1.00 70.79  ? 28   ILE   N C   1 
ATOM   173  O  O   . ILE   A 1 28  ? 139.116 150.567 173.066 1.00 70.79  ? 28   ILE   N O   1 
ATOM   174  C  CB  . ILE   A 1 28  ? 138.718 150.979 170.166 1.00 70.79  ? 28   ILE   N CB  1 
ATOM   175  C  CG1 . ILE   A 1 28  ? 140.198 151.362 170.106 1.00 70.79  ? 28   ILE   N CG1 1 
ATOM   176  C  CG2 . ILE   A 1 28  ? 137.785 152.099 170.669 1.00 70.79  ? 28   ILE   N CG2 1 
ATOM   177  C  CD1 . ILE   A 1 28  ? 140.488 152.430 169.096 1.00 70.79  ? 28   ILE   N CD1 1 
ATOM   178  N  N   . PHE   A 1 29  ? 139.767 148.444 172.613 1.00 70.63  ? 29   PHE   N N   1 
ATOM   179  C  CA  . PHE   A 1 29  ? 140.451 148.112 173.868 1.00 70.63  ? 29   PHE   N CA  1 
ATOM   180  C  C   . PHE   A 1 29  ? 139.493 148.069 175.058 1.00 70.63  ? 29   PHE   N C   1 
ATOM   181  O  O   . PHE   A 1 29  ? 139.872 147.627 176.148 1.00 70.63  ? 29   PHE   N O   1 
ATOM   182  C  CB  . PHE   A 1 29  ? 141.604 149.089 174.145 1.00 70.63  ? 29   PHE   N CB  1 
ATOM   183  C  CG  . PHE   A 1 29  ? 142.519 148.668 175.262 1.00 70.63  ? 29   PHE   N CG  1 
ATOM   184  C  CD1 . PHE   A 1 29  ? 142.922 147.352 175.389 1.00 70.63  ? 29   PHE   N CD1 1 
ATOM   185  C  CD2 . PHE   A 1 29  ? 142.975 149.595 176.182 1.00 70.63  ? 29   PHE   N CD2 1 
ATOM   186  C  CE1 . PHE   A 1 29  ? 143.755 146.969 176.415 1.00 70.63  ? 29   PHE   N CE1 1 
ATOM   187  C  CE2 . PHE   A 1 29  ? 143.814 149.219 177.208 1.00 70.63  ? 29   PHE   N CE2 1 
ATOM   188  C  CZ  . PHE   A 1 29  ? 144.204 147.906 177.324 1.00 70.63  ? 29   PHE   N CZ  1 
ATOM   189  N  N   . GLY   A 1 30  ? 138.236 148.446 174.845 1.00 73.52  ? 30   GLY   N N   1 
ATOM   190  C  CA  . GLY   A 1 30  ? 137.303 148.627 175.924 1.00 73.52  ? 30   GLY   N CA  1 
ATOM   191  C  C   . GLY   A 1 30  ? 137.816 149.633 176.933 1.00 73.52  ? 30   GLY   N C   1 
ATOM   192  O  O   . GLY   A 1 30  ? 138.175 150.766 176.601 1.00 73.52  ? 30   GLY   N O   1 
ATOM   193  N  N   . PRO   A 1 31  ? 137.892 149.210 178.189 1.00 71.82  ? 31   PRO   N N   1 
ATOM   194  C  CA  . PRO   A 1 31  ? 138.247 150.136 179.268 1.00 71.82  ? 31   PRO   N CA  1 
ATOM   195  C  C   . PRO   A 1 31  ? 139.738 150.415 179.357 1.00 71.82  ? 31   PRO   N C   1 
ATOM   196  O  O   . PRO   A 1 31  ? 140.571 149.510 179.279 1.00 71.82  ? 31   PRO   N O   1 
ATOM   197  C  CB  . PRO   A 1 31  ? 137.752 149.409 180.519 1.00 71.82  ? 31   PRO   N CB  1 
ATOM   198  C  CG  . PRO   A 1 31  ? 137.775 147.985 180.145 1.00 71.82  ? 31   PRO   N CG  1 
ATOM   199  C  CD  . PRO   A 1 31  ? 137.511 147.882 178.693 1.00 71.82  ? 31   PRO   N CD  1 
ATOM   200  N  N   . ASP   A 1 32  ? 140.065 151.696 179.535 1.00 71.07  ? 32   ASP   N N   1 
ATOM   201  C  CA  . ASP   A 1 32  ? 141.448 152.103 179.747 1.00 71.07  ? 32   ASP   N CA  1 
ATOM   202  C  C   . ASP   A 1 32  ? 141.924 151.765 181.154 1.00 71.07  ? 32   ASP   N C   1 
ATOM   203  O  O   . ASP   A 1 32  ? 143.050 151.290 181.333 1.00 71.07  ? 32   ASP   N O   1 
ATOM   204  C  CB  . ASP   A 1 32  ? 141.594 153.600 179.485 1.00 71.07  ? 32   ASP   N CB  1 
ATOM   205  C  CG  . ASP   A 1 32  ? 141.499 153.947 178.016 1.00 71.07  ? 32   ASP   N CG  1 
ATOM   206  O  OD1 . ASP   A 1 32  ? 141.427 153.019 177.185 1.00 71.07  ? 32   ASP   N OD1 1 
ATOM   207  O  OD2 . ASP   A 1 32  ? 141.493 155.152 177.692 1.00 71.07  ? 32   ASP   N OD2 1 
ATOM   208  N  N   . VAL   A 1 33  ? 141.088 152.006 182.160 1.00 66.68  ? 33   VAL   N N   1 
ATOM   209  C  CA  . VAL   A 1 33  ? 141.400 151.651 183.538 1.00 66.68  ? 33   VAL   N CA  1 
ATOM   210  C  C   . VAL   A 1 33  ? 140.214 150.878 184.099 1.00 66.68  ? 33   VAL   N C   1 
ATOM   211  O  O   . VAL   A 1 33  ? 139.066 151.087 183.696 1.00 66.68  ? 33   VAL   N O   1 
ATOM   212  C  CB  . VAL   A 1 33  ? 141.748 152.903 184.388 1.00 66.68  ? 33   VAL   N CB  1 
ATOM   213  C  CG1 . VAL   A 1 33  ? 140.521 153.731 184.698 1.00 66.68  ? 33   VAL   N CG1 1 
ATOM   214  C  CG2 . VAL   A 1 33  ? 142.470 152.520 185.666 1.00 66.68  ? 33   VAL   N CG2 1 
ATOM   215  N  N   . MET   A 1 34  ? 140.499 149.925 184.984 1.00 68.91  ? 34   MET   N N   1 
ATOM   216  C  CA  . MET   A 1 34  ? 139.470 149.052 185.521 1.00 68.91  ? 34   MET   N CA  1 
ATOM   217  C  C   . MET   A 1 34  ? 139.653 148.965 187.026 1.00 68.91  ? 34   MET   N C   1 
ATOM   218  O  O   . MET   A 1 34  ? 140.728 149.253 187.556 1.00 68.91  ? 34   MET   N O   1 
ATOM   219  C  CB  . MET   A 1 34  ? 139.535 147.647 184.912 1.00 68.91  ? 34   MET   N CB  1 
ATOM   220  C  CG  . MET   A 1 34  ? 139.215 147.630 183.436 1.00 68.91  ? 34   MET   N CG  1 
ATOM   221  S  SD  . MET   A 1 34  ? 139.337 146.030 182.623 1.00 68.91  ? 34   MET   N SD  1 
ATOM   222  C  CE  . MET   A 1 34  ? 137.914 145.218 183.319 1.00 68.91  ? 34   MET   N CE  1 
ATOM   223  N  N   . GLY   A 1 35  ? 138.593 148.566 187.715 1.00 67.57  ? 35   GLY   N N   1 
ATOM   224  C  CA  . GLY   A 1 35  ? 138.658 148.495 189.159 1.00 67.57  ? 35   GLY   N CA  1 
ATOM   225  C  C   . GLY   A 1 35  ? 137.537 147.668 189.736 1.00 67.57  ? 35   GLY   N C   1 
ATOM   226  O  O   . GLY   A 1 35  ? 136.509 147.427 189.097 1.00 67.57  ? 35   GLY   N O   1 
ATOM   227  N  N   . TRP   A 1 36  ? 137.761 147.228 190.964 1.00 74.99  ? 36   TRP   N N   1 
ATOM   228  C  CA  . TRP   A 1 36  ? 136.768 146.535 191.764 1.00 74.99  ? 36   TRP   N CA  1 
ATOM   229  C  C   . TRP   A 1 36  ? 136.374 147.429 192.928 1.00 74.99  ? 36   TRP   N C   1 
ATOM   230  O  O   . TRP   A 1 36  ? 137.244 148.024 193.580 1.00 74.99  ? 36   TRP   N O   1 
ATOM   231  C  CB  . TRP   A 1 36  ? 137.310 145.204 192.284 1.00 74.99  ? 36   TRP   N CB  1 
ATOM   232  C  CG  . TRP   A 1 36  ? 137.284 144.101 191.282 1.00 74.99  ? 36   TRP   N CG  1 
ATOM   233  C  CD1 . TRP   A 1 36  ? 138.329 143.647 190.538 1.00 74.99  ? 36   TRP   N CD1 1 
ATOM   234  C  CD2 . TRP   A 1 36  ? 136.159 143.295 190.929 1.00 74.99  ? 36   TRP   N CD2 1 
ATOM   235  N  NE1 . TRP   A 1 36  ? 137.923 142.613 189.734 1.00 74.99  ? 36   TRP   N NE1 1 
ATOM   236  C  CE2 . TRP   A 1 36  ? 136.593 142.379 189.956 1.00 74.99  ? 36   TRP   N CE2 1 
ATOM   237  C  CE3 . TRP   A 1 36  ? 134.825 143.262 191.338 1.00 74.99  ? 36   TRP   N CE3 1 
ATOM   238  C  CZ2 . TRP   A 1 36  ? 135.742 141.440 189.388 1.00 74.99  ? 36   TRP   N CZ2 1 
ATOM   239  C  CZ3 . TRP   A 1 36  ? 133.981 142.330 190.771 1.00 74.99  ? 36   TRP   N CZ3 1 
ATOM   240  C  CH2 . TRP   A 1 36  ? 134.442 141.432 189.807 1.00 74.99  ? 36   TRP   N CH2 1 
ATOM   241  N  N   . TYR   A 1 37  ? 135.068 147.528 193.162 1.00 73.23  ? 37   TYR   N N   1 
ATOM   242  C  CA  . TYR   A 1 37  ? 134.476 148.252 194.273 1.00 73.23  ? 37   TYR   N CA  1 
ATOM   243  C  C   . TYR   A 1 37  ? 133.750 147.260 195.167 1.00 73.23  ? 37   TYR   N C   1 
ATOM   244  O  O   . TYR   A 1 37  ? 133.275 146.224 194.699 1.00 73.23  ? 37   TYR   N O   1 
ATOM   245  C  CB  . TYR   A 1 37  ? 133.477 149.299 193.780 1.00 73.23  ? 37   TYR   N CB  1 
ATOM   246  C  CG  . TYR   A 1 37  ? 134.098 150.548 193.219 1.00 73.23  ? 37   TYR   N CG  1 
ATOM   247  C  CD1 . TYR   A 1 37  ? 135.183 151.137 193.831 1.00 73.23  ? 37   TYR   N CD1 1 
ATOM   248  C  CD2 . TYR   A 1 37  ? 133.604 151.132 192.070 1.00 73.23  ? 37   TYR   N CD2 1 
ATOM   249  C  CE1 . TYR   A 1 37  ? 135.753 152.283 193.325 1.00 73.23  ? 37   TYR   N CE1 1 
ATOM   250  C  CE2 . TYR   A 1 37  ? 134.168 152.278 191.554 1.00 73.23  ? 37   TYR   N CE2 1 
ATOM   251  C  CZ  . TYR   A 1 37  ? 135.246 152.847 192.186 1.00 73.23  ? 37   TYR   N CZ  1 
ATOM   252  O  OH  . TYR   A 1 37  ? 135.818 153.988 191.677 1.00 73.23  ? 37   TYR   N OH  1 
ATOM   253  N  N   . ARG   A 1 38  ? 133.645 147.583 196.451 1.00 74.50  ? 38   ARG   N N   1 
ATOM   254  C  CA  . ARG   A 1 38  ? 132.837 146.785 197.359 1.00 74.50  ? 38   ARG   N CA  1 
ATOM   255  C  C   . ARG   A 1 38  ? 131.883 147.687 198.121 1.00 74.50  ? 38   ARG   N C   1 
ATOM   256  O  O   . ARG   A 1 38  ? 132.174 148.859 198.375 1.00 74.50  ? 38   ARG   N O   1 
ATOM   257  C  CB  . ARG   A 1 38  ? 133.694 145.968 198.335 1.00 74.50  ? 38   ARG   N CB  1 
ATOM   258  C  CG  . ARG   A 1 38  ? 134.418 146.757 199.405 1.00 74.50  ? 38   ARG   N CG  1 
ATOM   259  C  CD  . ARG   A 1 38  ? 135.068 145.800 200.381 1.00 74.50  ? 38   ARG   N CD  1 
ATOM   260  N  NE  . ARG   A 1 38  ? 136.114 146.429 201.175 1.00 74.50  ? 38   ARG   N NE  1 
ATOM   261  C  CZ  . ARG   A 1 38  ? 136.978 145.762 201.928 1.00 74.50  ? 38   ARG   N CZ  1 
ATOM   262  N  NH1 . ARG   A 1 38  ? 136.954 144.441 202.000 1.00 74.50  ? 38   ARG   N NH1 1 
ATOM   263  N  NH2 . ARG   A 1 38  ? 137.889 146.435 202.624 1.00 74.50  ? 38   ARG   N NH2 1 
ATOM   264  N  N   . GLN   A 1 39  ? 130.723 147.135 198.459 1.00 84.14  ? 39   GLN   N N   1 
ATOM   265  C  CA  . GLN   A 1 39  ? 129.711 147.847 199.228 1.00 84.14  ? 39   GLN   N CA  1 
ATOM   266  C  C   . GLN   A 1 39  ? 129.219 146.925 200.334 1.00 84.14  ? 39   GLN   N C   1 
ATOM   267  O  O   . GLN   A 1 39  ? 128.565 145.913 200.059 1.00 84.14  ? 39   GLN   N O   1 
ATOM   268  C  CB  . GLN   A 1 39  ? 128.555 148.296 198.335 1.00 84.14  ? 39   GLN   N CB  1 
ATOM   269  C  CG  . GLN   A 1 39  ? 127.439 148.997 199.079 1.00 84.14  ? 39   GLN   N CG  1 
ATOM   270  C  CD  . GLN   A 1 39  ? 126.483 149.706 198.148 1.00 84.14  ? 39   GLN   N CD  1 
ATOM   271  O  OE1 . GLN   A 1 39  ? 125.724 149.070 197.420 1.00 84.14  ? 39   GLN   N OE1 1 
ATOM   272  N  NE2 . GLN   A 1 39  ? 126.516 151.032 198.164 1.00 84.14  ? 39   GLN   N NE2 1 
ATOM   273  N  N   . ALA   A 1 40  ? 129.558 147.261 201.573 1.00 92.47  ? 40   ALA   N N   1 
ATOM   274  C  CA  . ALA   A 1 40  ? 129.001 146.562 202.713 1.00 92.47  ? 40   ALA   N CA  1 
ATOM   275  C  C   . ALA   A 1 40  ? 127.512 146.887 202.829 1.00 92.47  ? 40   ALA   N C   1 
ATOM   276  O  O   . ALA   A 1 40  ? 127.064 147.931 202.347 1.00 92.47  ? 40   ALA   N O   1 
ATOM   277  C  CB  . ALA   A 1 40  ? 129.736 146.963 203.990 1.00 92.47  ? 40   ALA   N CB  1 
ATOM   278  N  N   . PRO   A 1 41  ? 126.717 145.993 203.422 1.00 96.83  ? 41   PRO   N N   1 
ATOM   279  C  CA  . PRO   A 1 41  ? 125.282 146.279 203.590 1.00 96.83  ? 41   PRO   N CA  1 
ATOM   280  C  C   . PRO   A 1 41  ? 125.054 147.485 204.489 1.00 96.83  ? 41   PRO   N C   1 
ATOM   281  O  O   . PRO   A 1 41  ? 125.502 147.525 205.637 1.00 96.83  ? 41   PRO   N O   1 
ATOM   282  C  CB  . PRO   A 1 41  ? 124.739 144.990 204.215 1.00 96.83  ? 41   PRO   N CB  1 
ATOM   283  C  CG  . PRO   A 1 41  ? 125.695 143.935 203.781 1.00 96.83  ? 41   PRO   N CG  1 
ATOM   284  C  CD  . PRO   A 1 41  ? 127.037 144.596 203.770 1.00 96.83  ? 41   PRO   N CD  1 
ATOM   285  N  N   . GLY   A 1 42  ? 124.346 148.474 203.949 1.00 99.60  ? 42   GLY   N N   1 
ATOM   286  C  CA  . GLY   A 1 42  ? 124.139 149.730 204.643 1.00 99.60  ? 42   GLY   N CA  1 
ATOM   287  C  C   . GLY   A 1 42  ? 125.387 150.567 204.817 1.00 99.60  ? 42   GLY   N C   1 
ATOM   288  O  O   . GLY   A 1 42  ? 125.526 151.251 205.836 1.00 99.60  ? 42   GLY   N O   1 
ATOM   289  N  N   . LYS   A 1 43  ? 126.297 150.540 203.845 1.00 94.88  ? 43   LYS   N N   1 
ATOM   290  C  CA  . LYS   A 1 43  ? 127.517 151.332 203.894 1.00 94.88  ? 43   LYS   N CA  1 
ATOM   291  C  C   . LYS   A 1 43  ? 127.850 151.818 202.491 1.00 94.88  ? 43   LYS   N C   1 
ATOM   292  O  O   . LYS   A 1 43  ? 127.407 151.248 201.491 1.00 94.88  ? 43   LYS   N O   1 
ATOM   293  C  CB  . LYS   A 1 43  ? 128.690 150.530 204.477 1.00 94.88  ? 43   LYS   N CB  1 
ATOM   294  C  CG  . LYS   A 1 43  ? 128.709 150.465 205.998 1.00 94.88  ? 43   LYS   N CG  1 
ATOM   295  C  CD  . LYS   A 1 43  ? 130.102 150.193 206.537 1.00 94.88  ? 43   LYS   N CD  1 
ATOM   296  C  CE  . LYS   A 1 43  ? 131.063 151.309 206.178 1.00 94.88  ? 43   LYS   N CE  1 
ATOM   297  N  NZ  . LYS   A 1 43  ? 132.473 150.931 206.469 1.00 94.88  ? 43   LYS   N NZ  1 
ATOM   298  N  N   . GLU   A 1 44  ? 128.638 152.887 202.428 1.00 94.12  ? 44   GLU   N N   1 
ATOM   299  C  CA  . GLU   A 1 44  ? 129.013 153.488 201.157 1.00 94.12  ? 44   GLU   N CA  1 
ATOM   300  C  C   . GLU   A 1 44  ? 130.040 152.625 200.424 1.00 94.12  ? 44   GLU   N C   1 
ATOM   301  O  O   . GLU   A 1 44  ? 130.735 151.797 201.018 1.00 94.12  ? 44   GLU   N O   1 
ATOM   302  C  CB  . GLU   A 1 44  ? 129.575 154.899 201.367 1.00 94.12  ? 44   GLU   N CB  1 
ATOM   303  C  CG  . GLU   A 1 44  ? 130.971 155.000 202.015 1.00 94.12  ? 44   GLU   N CG  1 
ATOM   304  C  CD  . GLU   A 1 44  ? 131.059 154.499 203.455 1.00 94.12  ? 44   GLU   N CD  1 
ATOM   305  O  OE1 . GLU   A 1 44  ? 132.193 154.370 203.961 1.00 94.12  ? 44   GLU   N OE1 1 
ATOM   306  O  OE2 . GLU   A 1 44  ? 130.012 154.270 204.097 1.00 94.12  ? 44   GLU   N OE2 1 
ATOM   307  N  N   . ARG   A 1 45  ? 130.126 152.831 199.111 1.00 83.46  ? 45   ARG   N N   1 
ATOM   308  C  CA  . ARG   A 1 45  ? 131.071 152.082 198.293 1.00 83.46  ? 45   ARG   N CA  1 
ATOM   309  C  C   . ARG   A 1 45  ? 132.504 152.515 198.572 1.00 83.46  ? 45   ARG   N C   1 
ATOM   310  O  O   . ARG   A 1 45  ? 132.782 153.690 198.825 1.00 83.46  ? 45   ARG   N O   1 
ATOM   311  C  CB  . ARG   A 1 45  ? 130.758 152.260 196.809 1.00 83.46  ? 45   ARG   N CB  1 
ATOM   312  C  CG  . ARG   A 1 45  ? 129.728 151.288 196.264 1.00 83.46  ? 45   ARG   N CG  1 
ATOM   313  C  CD  . ARG   A 1 45  ? 129.583 151.262 194.725 1.00 83.46  ? 45   ARG   N CD  1 
ATOM   314  N  NE  . ARG   A 1 45  ? 128.980 152.450 194.122 1.00 83.46  ? 45   ARG   N NE  1 
ATOM   315  C  CZ  . ARG   A 1 45  ? 129.598 153.594 193.846 1.00 83.46  ? 45   ARG   N CZ  1 
ATOM   316  N  NH1 . ARG   A 1 45  ? 130.911 153.717 193.939 1.00 83.46  ? 45   ARG   N NH1 1 
ATOM   317  N  NH2 . ARG   A 1 45  ? 128.881 154.627 193.414 1.00 83.46  ? 45   ARG   N NH2 1 
ATOM   318  N  N   . GLU   A 1 46  ? 133.417 151.552 198.512 1.00 74.79  ? 46   GLU   N N   1 
ATOM   319  C  CA  . GLU   A 1 46  ? 134.825 151.782 198.785 1.00 74.79  ? 46   GLU   N CA  1 
ATOM   320  C  C   . GLU   A 1 46  ? 135.650 151.241 197.628 1.00 74.79  ? 46   GLU   N C   1 
ATOM   321  O  O   . GLU   A 1 46  ? 135.322 150.205 197.044 1.00 74.79  ? 46   GLU   N O   1 
ATOM   322  C  CB  . GLU   A 1 46  ? 135.247 151.109 200.101 1.00 74.79  ? 46   GLU   N CB  1 
ATOM   323  C  CG  . GLU   A 1 46  ? 136.688 151.360 200.515 1.00 74.79  ? 46   GLU   N CG  1 
ATOM   324  C  CD  . GLU   A 1 46  ? 137.035 150.716 201.840 1.00 74.79  ? 46   GLU   N CD  1 
ATOM   325  O  OE1 . GLU   A 1 46  ? 136.154 150.054 202.425 1.00 74.79  ? 46   GLU   N OE1 1 
ATOM   326  O  OE2 . GLU   A 1 46  ? 138.186 150.875 202.301 1.00 74.79  ? 46   GLU   N OE2 1 
ATOM   327  N  N   . LEU   A 1 47  ? 136.718 151.957 197.288 1.00 70.62  ? 47   LEU   N N   1 
ATOM   328  C  CA  . LEU   A 1 47  ? 137.643 151.487 196.267 1.00 70.62  ? 47   LEU   N CA  1 
ATOM   329  C  C   . LEU   A 1 47  ? 138.530 150.408 196.865 1.00 70.62  ? 47   LEU   N C   1 
ATOM   330  O  O   . LEU   A 1 47  ? 139.339 150.687 197.757 1.00 70.62  ? 47   LEU   N O   1 
ATOM   331  C  CB  . LEU   A 1 47  ? 138.478 152.639 195.718 1.00 70.62  ? 47   LEU   N CB  1 
ATOM   332  C  CG  . LEU   A 1 47  ? 139.661 152.277 194.818 1.00 70.62  ? 47   LEU   N CG  1 
ATOM   333  C  CD1 . LEU   A 1 47  ? 139.213 151.499 193.595 1.00 70.62  ? 47   LEU   N CD1 1 
ATOM   334  C  CD2 . LEU   A 1 47  ? 140.382 153.532 194.393 1.00 70.62  ? 47   LEU   N CD2 1 
ATOM   335  N  N   . VAL   A 1 48  ? 138.378 149.177 196.382 1.00 72.77  ? 48   VAL   N N   1 
ATOM   336  C  CA  . VAL   A 1 48  ? 139.169 148.074 196.887 1.00 72.77  ? 48   VAL   N CA  1 
ATOM   337  C  C   . VAL   A 1 48  ? 140.264 147.646 195.910 1.00 72.77  ? 48   VAL   N C   1 
ATOM   338  O  O   . VAL   A 1 48  ? 141.327 147.198 196.358 1.00 72.77  ? 48   VAL   N O   1 
ATOM   339  C  CB  . VAL   A 1 48  ? 138.274 146.876 197.291 1.00 72.77  ? 48   VAL   N CB  1 
ATOM   340  C  CG1 . VAL   A 1 48  ? 137.632 146.204 196.105 1.00 72.77  ? 48   VAL   N CG1 1 
ATOM   341  C  CG2 . VAL   A 1 48  ? 139.035 145.868 198.134 1.00 72.77  ? 48   VAL   N CG2 1 
ATOM   342  N  N   . ALA   A 1 49  ? 140.082 147.831 194.600 1.00 70.28  ? 49   ALA   N N   1 
ATOM   343  C  CA  . ALA   A 1 49  ? 141.166 147.486 193.687 1.00 70.28  ? 49   ALA   N CA  1 
ATOM   344  C  C   . ALA   A 1 49  ? 141.090 148.327 192.424 1.00 70.28  ? 49   ALA   N C   1 
ATOM   345  O  O   . ALA   A 1 49  ? 140.004 148.670 191.959 1.00 70.28  ? 49   ALA   N O   1 
ATOM   346  C  CB  . ALA   A 1 49  ? 141.135 145.999 193.321 1.00 70.28  ? 49   ALA   N CB  1 
ATOM   347  N  N   . GLY   A 1 50  ? 142.257 148.635 191.859 1.00 66.91  ? 50   GLY   N N   1 
ATOM   348  C  CA  . GLY   A 1 50  ? 142.306 149.328 190.582 1.00 66.91  ? 50   GLY   N CA  1 
ATOM   349  C  C   . GLY   A 1 50  ? 143.571 149.064 189.789 1.00 66.91  ? 50   GLY   N C   1 
ATOM   350  O  O   . GLY   A 1 50  ? 144.645 148.920 190.375 1.00 66.91  ? 50   GLY   N O   1 
ATOM   351  N  N   . ILE   A 1 51  ? 143.470 149.009 188.462 1.00 67.94  ? 51   ILE   N N   1 
ATOM   352  C  CA  . ILE   A 1 51  ? 144.626 148.733 187.612 1.00 67.94  ? 51   ILE   N CA  1 
ATOM   353  C  C   . ILE   A 1 51  ? 144.364 149.306 186.225 1.00 67.94  ? 51   ILE   N C   1 
ATOM   354  O  O   . ILE   A 1 51  ? 143.222 149.349 185.760 1.00 67.94  ? 51   ILE   N O   1 
ATOM   355  C  CB  . ILE   A 1 51  ? 144.935 147.215 187.556 1.00 67.94  ? 51   ILE   N CB  1 
ATOM   356  C  CG1 . ILE   A 1 51  ? 146.298 146.944 186.912 1.00 67.94  ? 51   ILE   N CG1 1 
ATOM   357  C  CG2 . ILE   A 1 51  ? 143.834 146.437 186.840 1.00 67.94  ? 51   ILE   N CG2 1 
ATOM   358  C  CD1 . ILE   A 1 51  ? 146.648 145.485 186.806 1.00 67.94  ? 51   ILE   N CD1 1 
ATOM   359  N  N   . SER   A 1 52  ? 145.428 149.762 185.564 1.00 66.52  ? 52   SER   N N   1 
ATOM   360  C  CA  . SER   A 1 52  ? 145.377 150.052 184.138 1.00 66.52  ? 52   SER   N CA  1 
ATOM   361  C  C   . SER   A 1 52  ? 146.194 149.046 183.337 1.00 66.52  ? 52   SER   N C   1 
ATOM   362  O  O   . SER   A 1 52  ? 145.634 148.322 182.509 1.00 66.52  ? 52   SER   N O   1 
ATOM   363  C  CB  . SER   A 1 52  ? 145.870 151.479 183.872 1.00 66.52  ? 52   SER   N CB  1 
ATOM   364  O  OG  . SER   A 1 52  ? 147.276 151.562 184.005 1.00 66.52  ? 52   SER   N OG  1 
ATOM   365  N  N   . ASN   A 1 53  ? 147.498 148.954 183.599 1.00 72.20  ? 53   ASN   N N   1 
ATOM   366  C  CA  . ASN   A 1 53  ? 148.370 147.935 183.026 1.00 72.20  ? 53   ASN   N CA  1 
ATOM   367  C  C   . ASN   A 1 53  ? 149.668 147.859 183.820 1.00 72.20  ? 53   ASN   N C   1 
ATOM   368  O  O   . ASN   A 1 53  ? 150.056 148.819 184.489 1.00 72.20  ? 53   ASN   N O   1 
ATOM   369  C  CB  . ASN   A 1 53  ? 148.617 148.157 181.512 1.00 72.20  ? 53   ASN   N CB  1 
ATOM   370  C  CG  . ASN   A 1 53  ? 149.551 149.343 181.172 1.00 72.20  ? 53   ASN   N CG  1 
ATOM   371  O  OD1 . ASN   A 1 53  ? 150.011 150.104 182.022 1.00 72.20  ? 53   ASN   N OD1 1 
ATOM   372  N  ND2 . ASN   A 1 53  ? 149.829 149.481 179.882 1.00 72.20  ? 53   ASN   N ND2 1 
ATOM   373  N  N   . GLY   A 1 54  ? 150.322 146.702 183.739 1.00 71.56  ? 54   GLY   N N   1 
ATOM   374  C  CA  . GLY   A 1 54  ? 151.638 146.535 184.337 1.00 71.56  ? 54   GLY   N CA  1 
ATOM   375  C  C   . GLY   A 1 54  ? 151.625 146.705 185.843 1.00 71.56  ? 54   GLY   N C   1 
ATOM   376  O  O   . GLY   A 1 54  ? 150.780 146.147 186.551 1.00 71.56  ? 54   GLY   N O   1 
ATOM   377  N  N   . ALA   A 1 55  ? 152.577 147.489 186.340 1.00 73.02  ? 55   ALA   N N   1 
ATOM   378  C  CA  . ALA   A 1 55  ? 152.672 147.810 187.763 1.00 73.02  ? 55   ALA   N CA  1 
ATOM   379  C  C   . ALA   A 1 55  ? 151.950 149.115 188.092 1.00 73.02  ? 55   ALA   N C   1 
ATOM   380  O  O   . ALA   A 1 55  ? 152.511 150.034 188.686 1.00 73.02  ? 55   ALA   N O   1 
ATOM   381  C  CB  . ALA   A 1 55  ? 154.135 147.869 188.184 1.00 73.02  ? 55   ALA   N CB  1 
ATOM   382  N  N   . ASN   A 1 56  ? 150.685 149.199 187.696 1.00 71.79  ? 56   ASN   N N   1 
ATOM   383  C  CA  . ASN   A 1 56  ? 149.817 150.325 188.012 1.00 71.79  ? 56   ASN   N CA  1 
ATOM   384  C  C   . ASN   A 1 56  ? 148.661 149.864 188.885 1.00 71.79  ? 56   ASN   N C   1 
ATOM   385  O  O   . ASN   A 1 56  ? 147.502 150.212 188.656 1.00 71.79  ? 56   ASN   N O   1 
ATOM   386  C  CB  . ASN   A 1 56  ? 149.300 150.997 186.744 1.00 71.79  ? 56   ASN   N CB  1 
ATOM   387  C  CG  . ASN   A 1 56  ? 150.397 151.700 185.972 1.00 71.79  ? 56   ASN   N CG  1 
ATOM   388  O  OD1 . ASN   A 1 56  ? 150.798 152.812 186.314 1.00 71.79  ? 56   ASN   N OD1 1 
ATOM   389  N  ND2 . ASN   A 1 56  ? 150.894 151.049 184.927 1.00 71.79  ? 56   ASN   N ND2 1 
ATOM   390  N  N   . THR   A 1 57  ? 148.969 149.051 189.887 1.00 72.17  ? 57   THR   N N   1 
ATOM   391  C  CA  . THR   A 1 57  ? 147.957 148.484 190.760 1.00 72.17  ? 57   THR   N CA  1 
ATOM   392  C  C   . THR   A 1 57  ? 147.798 149.336 192.009 1.00 72.17  ? 57   THR   N C   1 
ATOM   393  O  O   . THR   A 1 57  ? 148.783 149.794 192.594 1.00 72.17  ? 57   THR   N O   1 
ATOM   394  C  CB  . THR   A 1 57  ? 148.331 147.057 191.160 1.00 72.17  ? 57   THR   N CB  1 
ATOM   395  O  OG1 . THR   A 1 57  ? 149.569 147.077 191.880 1.00 72.17  ? 57   THR   N OG1 1 
ATOM   396  C  CG2 . THR   A 1 57  ? 148.496 146.191 189.931 1.00 72.17  ? 57   THR   N CG2 1 
ATOM   397  N  N   . TYR   A 1 58  ? 146.549 149.545 192.411 1.00 67.26  ? 58   TYR   N N   1 
ATOM   398  C  CA  . TYR   A 1 58  ? 146.229 150.203 193.666 1.00 67.26  ? 58   TYR   N CA  1 
ATOM   399  C  C   . TYR   A 1 58  ? 145.311 149.305 194.475 1.00 67.26  ? 58   TYR   N C   1 
ATOM   400  O  O   . TYR   A 1 58  ? 144.268 148.866 193.978 1.00 67.26  ? 58   TYR   N O   1 
ATOM   401  C  CB  . TYR   A 1 58  ? 145.559 151.558 193.448 1.00 67.26  ? 58   TYR   N CB  1 
ATOM   402  C  CG  . TYR   A 1 58  ? 145.119 152.221 194.733 1.00 67.26  ? 58   TYR   N CG  1 
ATOM   403  C  CD1 . TYR   A 1 58  ? 146.049 152.748 195.617 1.00 67.26  ? 58   TYR   N CD1 1 
ATOM   404  C  CD2 . TYR   A 1 58  ? 143.774 152.309 195.067 1.00 67.26  ? 58   TYR   N CD2 1 
ATOM   405  C  CE1 . TYR   A 1 58  ? 145.653 153.351 196.793 1.00 67.26  ? 58   TYR   N CE1 1 
ATOM   406  C  CE2 . TYR   A 1 58  ? 143.371 152.907 196.242 1.00 67.26  ? 58   TYR   N CE2 1 
ATOM   407  C  CZ  . TYR   A 1 58  ? 144.313 153.427 197.099 1.00 67.26  ? 58   TYR   N CZ  1 
ATOM   408  O  OH  . TYR   A 1 58  ? 143.911 154.025 198.269 1.00 67.26  ? 58   TYR   N OH  1 
ATOM   409  N  N   . TYR   A 1 59  ? 145.706 149.040 195.714 1.00 73.17  ? 59   TYR   N N   1 
ATOM   410  C  CA  . TYR   A 1 59  ? 144.865 148.386 196.699 1.00 73.17  ? 59   TYR   N CA  1 
ATOM   411  C  C   . TYR   A 1 59  ? 144.745 149.307 197.900 1.00 73.17  ? 59   TYR   N C   1 
ATOM   412  O  O   . TYR   A 1 59  ? 145.683 150.037 198.232 1.00 73.17  ? 59   TYR   N O   1 
ATOM   413  C  CB  . TYR   A 1 59  ? 145.437 147.035 197.127 1.00 73.17  ? 59   TYR   N CB  1 
ATOM   414  C  CG  . TYR   A 1 59  ? 145.950 146.215 195.974 1.00 73.17  ? 59   TYR   N CG  1 
ATOM   415  C  CD1 . TYR   A 1 59  ? 145.072 145.634 195.077 1.00 73.17  ? 59   TYR   N CD1 1 
ATOM   416  C  CD2 . TYR   A 1 59  ? 147.310 146.034 195.773 1.00 73.17  ? 59   TYR   N CD2 1 
ATOM   417  C  CE1 . TYR   A 1 59  ? 145.529 144.887 194.017 1.00 73.17  ? 59   TYR   N CE1 1 
ATOM   418  C  CE2 . TYR   A 1 59  ? 147.778 145.290 194.712 1.00 73.17  ? 59   TYR   N CE2 1 
ATOM   419  C  CZ  . TYR   A 1 59  ? 146.880 144.720 193.836 1.00 73.17  ? 59   TYR   N CZ  1 
ATOM   420  O  OH  . TYR   A 1 59  ? 147.332 143.974 192.773 1.00 73.17  ? 59   TYR   N OH  1 
ATOM   421  N  N   . ALA   A 1 60  ? 143.583 149.275 198.543 1.00 76.03  ? 60   ALA   N N   1 
ATOM   422  C  CA  . ALA   A 1 60  ? 143.348 150.132 199.691 1.00 76.03  ? 60   ALA   N CA  1 
ATOM   423  C  C   . ALA   A 1 60  ? 144.221 149.700 200.866 1.00 76.03  ? 60   ALA   N C   1 
ATOM   424  O  O   . ALA   A 1 60  ? 144.783 148.601 200.888 1.00 76.03  ? 60   ALA   N O   1 
ATOM   425  C  CB  . ALA   A 1 60  ? 141.873 150.107 200.087 1.00 76.03  ? 60   ALA   N CB  1 
ATOM   426  N  N   . ASP   A 1 61  ? 144.342 150.595 201.849 1.00 82.06  ? 61   ASP   N N   1 
ATOM   427  C  CA  . ASP   A 1 61  ? 145.181 150.327 203.012 1.00 82.06  ? 61   ASP   N CA  1 
ATOM   428  C  C   . ASP   A 1 61  ? 144.656 149.177 203.862 1.00 82.06  ? 61   ASP   N C   1 
ATOM   429  O  O   . ASP   A 1 61  ? 145.434 148.564 204.599 1.00 82.06  ? 61   ASP   N O   1 
ATOM   430  C  CB  . ASP   A 1 61  ? 145.307 151.587 203.867 1.00 82.06  ? 61   ASP   N CB  1 
ATOM   431  C  CG  . ASP   A 1 61  ? 146.453 152.474 203.429 1.00 82.06  ? 61   ASP   N CG  1 
ATOM   432  O  OD1 . ASP   A 1 61  ? 147.269 152.024 202.599 1.00 82.06  ? 61   ASP   N OD1 1 
ATOM   433  O  OD2 . ASP   A 1 61  ? 146.537 153.622 203.914 1.00 82.06  ? 61   ASP   N OD2 1 
ATOM   434  N  N   . SER   A 1 62  ? 143.365 148.872 203.778 1.00 80.01  ? 62   SER   N N   1 
ATOM   435  C  CA  . SER   A 1 62  ? 142.787 147.759 204.515 1.00 80.01  ? 62   SER   N CA  1 
ATOM   436  C  C   . SER   A 1 62  ? 142.871 146.436 203.767 1.00 80.01  ? 62   SER   N C   1 
ATOM   437  O  O   . SER   A 1 62  ? 142.559 145.394 204.353 1.00 80.01  ? 62   SER   N O   1 
ATOM   438  C  CB  . SER   A 1 62  ? 141.323 148.055 204.849 1.00 80.01  ? 62   SER   N CB  1 
ATOM   439  O  OG  . SER   A 1 62  ? 140.519 147.995 203.684 1.00 80.01  ? 62   SER   N OG  1 
ATOM   440  N  N   . VAL   A 1 63  ? 143.266 146.445 202.495 1.00 79.53  ? 63   VAL   N N   1 
ATOM   441  C  CA  . VAL   A 1 63  ? 143.326 145.220 201.703 1.00 79.53  ? 63   VAL   N CA  1 
ATOM   442  C  C   . VAL   A 1 63  ? 144.692 145.078 201.047 1.00 79.53  ? 63   VAL   N C   1 
ATOM   443  O  O   . VAL   A 1 63  ? 144.884 144.226 200.173 1.00 79.53  ? 63   VAL   N O   1 
ATOM   444  C  CB  . VAL   A 1 63  ? 142.217 145.184 200.639 1.00 79.53  ? 63   VAL   N CB  1 
ATOM   445  C  CG1 . VAL   A 1 63  ? 140.845 145.142 201.289 1.00 79.53  ? 63   VAL   N CG1 1 
ATOM   446  C  CG2 . VAL   A 1 63  ? 142.344 146.375 199.717 1.00 79.53  ? 63   VAL   N CG2 1 
ATOM   447  N  N   . LYS   A 1 64  ? 145.646 145.909 201.454 1.00 82.39  ? 64   LYS   N N   1 
ATOM   448  C  CA  . LYS   A 1 64  ? 146.983 145.835 200.882 1.00 82.39  ? 64   LYS   N CA  1 
ATOM   449  C  C   . LYS   A 1 64  ? 147.716 144.616 201.424 1.00 82.39  ? 64   LYS   N C   1 
ATOM   450  O  O   . LYS   A 1 64  ? 147.737 144.377 202.635 1.00 82.39  ? 64   LYS   N O   1 
ATOM   451  C  CB  . LYS   A 1 64  ? 147.766 147.109 201.190 1.00 82.39  ? 64   LYS   N CB  1 
ATOM   452  C  CG  . LYS   A 1 64  ? 148.921 147.368 200.234 1.00 82.39  ? 64   LYS   N CG  1 
ATOM   453  C  CD  . LYS   A 1 64  ? 149.611 148.686 200.539 1.00 82.39  ? 64   LYS   N CD  1 
ATOM   454  C  CE  . LYS   A 1 64  ? 148.629 149.845 200.511 1.00 82.39  ? 64   LYS   N CE  1 
ATOM   455  N  NZ  . LYS   A 1 64  ? 148.050 150.056 199.156 1.00 82.39  ? 64   LYS   N NZ  1 
ATOM   456  N  N   . GLY   A 1 65  ? 148.320 143.843 200.522 1.00 85.66  ? 65   GLY   N N   1 
ATOM   457  C  CA  . GLY   A 1 65  ? 149.000 142.619 200.883 1.00 85.66  ? 65   GLY   N CA  1 
ATOM   458  C  C   . GLY   A 1 65  ? 148.131 141.380 200.880 1.00 85.66  ? 65   GLY   N C   1 
ATOM   459  O  O   . GLY   A 1 65  ? 148.660 140.273 201.035 1.00 85.66  ? 65   GLY   N O   1 
ATOM   460  N  N   . ARG   A 1 66  ? 146.819 141.530 200.705 1.00 86.42  ? 66   ARG   N N   1 
ATOM   461  C  CA  . ARG   A 1 66  ? 145.904 140.400 200.653 1.00 86.42  ? 66   ARG   N CA  1 
ATOM   462  C  C   . ARG   A 1 66  ? 145.016 140.399 199.418 1.00 86.42  ? 66   ARG   N C   1 
ATOM   463  O  O   . ARG   A 1 66  ? 144.289 139.423 199.205 1.00 86.42  ? 66   ARG   N O   1 
ATOM   464  C  CB  . ARG   A 1 66  ? 145.016 140.373 201.907 1.00 86.42  ? 66   ARG   N CB  1 
ATOM   465  C  CG  . ARG   A 1 66  ? 144.108 141.577 202.014 1.00 86.42  ? 66   ARG   N CG  1 
ATOM   466  C  CD  . ARG   A 1 66  ? 142.836 141.285 202.785 1.00 86.42  ? 66   ARG   N CD  1 
ATOM   467  N  NE  . ARG   A 1 66  ? 143.032 141.392 204.225 1.00 86.42  ? 66   ARG   N NE  1 
ATOM   468  C  CZ  . ARG   A 1 66  ? 142.048 141.385 205.113 1.00 86.42  ? 66   ARG   N CZ  1 
ATOM   469  N  NH1 . ARG   A 1 66  ? 140.783 141.274 204.741 1.00 86.42  ? 66   ARG   N NH1 1 
ATOM   470  N  NH2 . ARG   A 1 66  ? 142.340 141.494 206.405 1.00 86.42  ? 66   ARG   N NH2 1 
ATOM   471  N  N   . PHE   A 1 67  ? 145.041 141.454 198.610 1.00 79.86  ? 67   PHE   N N   1 
ATOM   472  C  CA  . PHE   A 1 67  ? 144.280 141.539 197.372 1.00 79.86  ? 67   PHE   N CA  1 
ATOM   473  C  C   . PHE   A 1 67  ? 145.250 141.791 196.229 1.00 79.86  ? 67   PHE   N C   1 
ATOM   474  O  O   . PHE   A 1 67  ? 146.096 142.686 196.321 1.00 79.86  ? 67   PHE   N O   1 
ATOM   475  C  CB  . PHE   A 1 67  ? 143.253 142.669 197.441 1.00 79.86  ? 67   PHE   N CB  1 
ATOM   476  C  CG  . PHE   A 1 67  ? 141.924 142.261 198.005 1.00 79.86  ? 67   PHE   N CG  1 
ATOM   477  C  CD1 . PHE   A 1 67  ? 140.793 142.258 197.208 1.00 79.86  ? 67   PHE   N CD1 1 
ATOM   478  C  CD2 . PHE   A 1 67  ? 141.805 141.876 199.329 1.00 79.86  ? 67   PHE   N CD2 1 
ATOM   479  C  CE1 . PHE   A 1 67  ? 139.566 141.895 197.729 1.00 79.86  ? 67   PHE   N CE1 1 
ATOM   480  C  CE2 . PHE   A 1 67  ? 140.581 141.505 199.854 1.00 79.86  ? 67   PHE   N CE2 1 
ATOM   481  C  CZ  . PHE   A 1 67  ? 139.461 141.514 199.052 1.00 79.86  ? 67   PHE   N CZ  1 
ATOM   482  N  N   . THR   A 1 68  ? 145.142 141.003 195.163 1.00 80.17  ? 68   THR   N N   1 
ATOM   483  C  CA  . THR   A 1 68  ? 145.947 141.217 193.968 1.00 80.17  ? 68   THR   N CA  1 
ATOM   484  C  C   . THR   A 1 68  ? 145.043 141.277 192.749 1.00 80.17  ? 68   THR   N C   1 
ATOM   485  O  O   . THR   A 1 68  ? 144.086 140.507 192.632 1.00 80.17  ? 68   THR   N O   1 
ATOM   486  C  CB  . THR   A 1 68  ? 147.002 140.120 193.771 1.00 80.17  ? 68   THR   N CB  1 
ATOM   487  O  OG1 . THR   A 1 68  ? 146.354 138.852 193.617 1.00 80.17  ? 68   THR   N OG1 1 
ATOM   488  C  CG2 . THR   A 1 68  ? 147.975 140.073 194.944 1.00 80.17  ? 68   THR   N CG2 1 
ATOM   489  N  N   . ILE   A 1 69  ? 145.362 142.180 191.830 1.00 74.99  ? 69   ILE   N N   1 
ATOM   490  C  CA  . ILE   A 1 69  ? 144.542 142.417 190.652 1.00 74.99  ? 69   ILE   N CA  1 
ATOM   491  C  C   . ILE   A 1 69  ? 145.380 142.139 189.411 1.00 74.99  ? 69   ILE   N C   1 
ATOM   492  O  O   . ILE   A 1 69  ? 146.587 142.403 189.384 1.00 74.99  ? 69   ILE   N O   1 
ATOM   493  C  CB  . ILE   A 1 69  ? 143.953 143.848 190.653 1.00 74.99  ? 69   ILE   N CB  1 
ATOM   494  C  CG1 . ILE   A 1 69  ? 142.887 144.000 189.576 1.00 74.99  ? 69   ILE   N CG1 1 
ATOM   495  C  CG2 . ILE   A 1 69  ? 145.026 144.911 190.501 1.00 74.99  ? 69   ILE   N CG2 1 
ATOM   496  C  CD1 . ILE   A 1 69  ? 141.968 145.163 189.802 1.00 74.99  ? 69   ILE   N CD1 1 
ATOM   497  N  N   . SER   A 1 70  ? 144.751 141.534 188.409 1.00 77.46  ? 70   SER   N N   1 
ATOM   498  C  CA  . SER   A 1 70  ? 145.421 141.226 187.159 1.00 77.46  ? 70   SER   N CA  1 
ATOM   499  C  C   . SER   A 1 70  ? 144.476 141.525 186.010 1.00 77.46  ? 70   SER   N C   1 
ATOM   500  O  O   . SER   A 1 70  ? 143.256 141.465 186.162 1.00 77.46  ? 70   SER   N O   1 
ATOM   501  C  CB  . SER   A 1 70  ? 145.871 139.762 187.105 1.00 77.46  ? 70   SER   N CB  1 
ATOM   502  O  OG  . SER   A 1 70  ? 144.809 138.890 187.454 1.00 77.46  ? 70   SER   N OG  1 
ATOM   503  N  N   . ARG   A 1 71  ? 145.049 141.847 184.857 1.00 75.30  ? 71   ARG   N N   1 
ATOM   504  C  CA  . ARG   A 1 71  ? 144.269 142.140 183.666 1.00 75.30  ? 71   ARG   N CA  1 
ATOM   505  C  C   . ARG   A 1 71  ? 144.755 141.269 182.521 1.00 75.30  ? 71   ARG   N C   1 
ATOM   506  O  O   . ARG   A 1 71  ? 145.962 141.178 182.276 1.00 75.30  ? 71   ARG   N O   1 
ATOM   507  C  CB  . ARG   A 1 71  ? 144.371 143.618 183.288 1.00 75.30  ? 71   ARG   N CB  1 
ATOM   508  C  CG  . ARG   A 1 71  ? 143.455 144.008 182.145 1.00 75.30  ? 71   ARG   N CG  1 
ATOM   509  C  CD  . ARG   A 1 71  ? 143.764 145.393 181.628 1.00 75.30  ? 71   ARG   N CD  1 
ATOM   510  N  NE  . ARG   A 1 71  ? 142.758 145.835 180.673 1.00 75.30  ? 71   ARG   N NE  1 
ATOM   511  C  CZ  . ARG   A 1 71  ? 142.314 147.079 180.578 1.00 75.30  ? 71   ARG   N CZ  1 
ATOM   512  N  NH1 . ARG   A 1 71  ? 142.774 148.037 181.363 1.00 75.30  ? 71   ARG   N NH1 1 
ATOM   513  N  NH2 . ARG   A 1 71  ? 141.384 147.367 179.674 1.00 75.30  ? 71   ARG   N NH2 1 
ATOM   514  N  N   . ASP   A 1 72  ? 143.821 140.628 181.828 1.00 84.35  ? 72   ASP   N N   1 
ATOM   515  C  CA  . ASP   A 1 72  ? 144.122 139.865 180.625 1.00 84.35  ? 72   ASP   N CA  1 
ATOM   516  C  C   . ASP   A 1 72  ? 143.629 140.720 179.465 1.00 84.35  ? 72   ASP   N C   1 
ATOM   517  O  O   . ASP   A 1 72  ? 142.444 141.068 179.404 1.00 84.35  ? 72   ASP   N O   1 
ATOM   518  C  CB  . ASP   A 1 72  ? 143.451 138.483 180.687 1.00 84.35  ? 72   ASP   N CB  1 
ATOM   519  C  CG  . ASP   A 1 72  ? 143.581 137.642 179.392 1.00 84.35  ? 72   ASP   N CG  1 
ATOM   520  O  OD1 . ASP   A 1 72  ? 143.644 136.406 179.550 1.00 84.35  ? 72   ASP   N OD1 1 
ATOM   521  O  OD2 . ASP   A 1 72  ? 143.595 138.133 178.243 1.00 84.35  ? 72   ASP   N OD2 1 
ATOM   522  N  N   . ASN   A 1 73  ? 144.541 141.057 178.555 1.00 84.40  ? 73   ASN   N N   1 
ATOM   523  C  CA  . ASN   A 1 73  ? 144.221 141.919 177.428 1.00 84.40  ? 73   ASN   N CA  1 
ATOM   524  C  C   . ASN   A 1 73  ? 143.766 141.149 176.199 1.00 84.40  ? 73   ASN   N C   1 
ATOM   525  O  O   . ASN   A 1 73  ? 143.154 141.744 175.305 1.00 84.40  ? 73   ASN   N O   1 
ATOM   526  C  CB  . ASN   A 1 73  ? 145.433 142.779 177.062 1.00 84.40  ? 73   ASN   N CB  1 
ATOM   527  C  CG  . ASN   A 1 73  ? 146.056 143.449 178.268 1.00 84.40  ? 73   ASN   N CG  1 
ATOM   528  O  OD1 . ASN   A 1 73  ? 145.360 144.044 179.087 1.00 84.40  ? 73   ASN   N OD1 1 
ATOM   529  N  ND2 . ASN   A 1 73  ? 147.375 143.357 178.384 1.00 84.40  ? 73   ASN   N ND2 1 
ATOM   530  N  N   . ALA   A 1 74  ? 144.060 139.849 176.125 1.00 83.96  ? 74   ALA   N N   1 
ATOM   531  C  CA  . ALA   A 1 74  ? 143.609 139.054 174.987 1.00 83.96  ? 74   ALA   N CA  1 
ATOM   532  C  C   . ALA   A 1 74  ? 142.099 138.864 175.014 1.00 83.96  ? 74   ALA   N C   1 
ATOM   533  O  O   . ALA   A 1 74  ? 141.455 138.815 173.961 1.00 83.96  ? 74   ALA   N O   1 
ATOM   534  C  CB  . ALA   A 1 74  ? 144.324 137.705 174.972 1.00 83.96  ? 74   ALA   N CB  1 
ATOM   535  N  N   . LYS   A 1 75  ? 141.520 138.751 176.207 1.00 82.62  ? 75   LYS   N N   1 
ATOM   536  C  CA  . LYS   A 1 75  ? 140.079 138.630 176.368 1.00 82.62  ? 75   LYS   N CA  1 
ATOM   537  C  C   . LYS   A 1 75  ? 139.446 139.866 176.988 1.00 82.62  ? 75   LYS   N C   1 
ATOM   538  O  O   . LYS   A 1 75  ? 138.218 139.905 177.125 1.00 82.62  ? 75   LYS   N O   1 
ATOM   539  C  CB  . LYS   A 1 75  ? 139.745 137.397 177.215 1.00 82.62  ? 75   LYS   N CB  1 
ATOM   540  C  CG  . LYS   A 1 75  ? 140.069 136.078 176.534 1.00 82.62  ? 75   LYS   N CG  1 
ATOM   541  C  CD  . LYS   A 1 75  ? 139.811 134.902 177.460 1.00 82.62  ? 75   LYS   N CD  1 
ATOM   542  C  CE  . LYS   A 1 75  ? 140.627 135.021 178.737 1.00 82.62  ? 75   LYS   N CE  1 
ATOM   543  N  NZ  . LYS   A 1 75  ? 140.304 133.942 179.707 1.00 82.62  ? 75   LYS   N NZ  1 
ATOM   544  N  N   . ASN   A 1 76  ? 140.253 140.865 177.364 1.00 80.08  ? 76   ASN   N N   1 
ATOM   545  C  CA  . ASN   A 1 76  ? 139.799 142.136 177.938 1.00 80.08  ? 76   ASN   N CA  1 
ATOM   546  C  C   . ASN   A 1 76  ? 138.982 141.914 179.214 1.00 80.08  ? 76   ASN   N C   1 
ATOM   547  O  O   . ASN   A 1 76  ? 137.799 142.248 179.300 1.00 80.08  ? 76   ASN   N O   1 
ATOM   548  C  CB  . ASN   A 1 76  ? 139.014 142.956 176.904 1.00 80.08  ? 76   ASN   N CB  1 
ATOM   549  C  CG  . ASN   A 1 76  ? 138.921 144.421 177.271 1.00 80.08  ? 76   ASN   N CG  1 
ATOM   550  O  OD1 . ASN   A 1 76  ? 139.560 144.877 178.217 1.00 80.08  ? 76   ASN   N OD1 1 
ATOM   551  N  ND2 . ASN   A 1 76  ? 138.118 145.169 176.522 1.00 80.08  ? 76   ASN   N ND2 1 
ATOM   552  N  N   . THR   A 1 77  ? 139.645 141.343 180.218 1.00 78.89  ? 77   THR   N N   1 
ATOM   553  C  CA  . THR   A 1 77  ? 138.986 141.003 181.470 1.00 78.89  ? 77   THR   N CA  1 
ATOM   554  C  C   . THR   A 1 77  ? 139.914 141.294 182.640 1.00 78.89  ? 77   THR   N C   1 
ATOM   555  O  O   . THR   A 1 77  ? 141.123 141.471 182.474 1.00 78.89  ? 77   THR   N O   1 
ATOM   556  C  CB  . THR   A 1 77  ? 138.559 139.532 181.501 1.00 78.89  ? 77   THR   N CB  1 
ATOM   557  O  OG1 . THR   A 1 77  ? 137.984 139.230 182.778 1.00 78.89  ? 77   THR   N OG1 1 
ATOM   558  C  CG2 . THR   A 1 77  ? 139.753 138.633 181.263 1.00 78.89  ? 77   THR   N CG2 1 
ATOM   559  N  N   . VAL   A 1 78  ? 139.328 141.339 183.835 1.00 77.39  ? 78   VAL   N N   1 
ATOM   560  C  CA  . VAL   A 1 78  ? 140.068 141.591 185.064 1.00 77.39  ? 78   VAL   N CA  1 
ATOM   561  C  C   . VAL   A 1 78  ? 139.786 140.455 186.040 1.00 77.39  ? 78   VAL   N C   1 
ATOM   562  O  O   . VAL   A 1 78  ? 138.669 139.924 186.095 1.00 77.39  ? 78   VAL   N O   1 
ATOM   563  C  CB  . VAL   A 1 78  ? 139.720 142.970 185.681 1.00 77.39  ? 78   VAL   N CB  1 
ATOM   564  C  CG1 . VAL   A 1 78  ? 138.281 143.043 186.146 1.00 77.39  ? 78   VAL   N CG1 1 
ATOM   565  C  CG2 . VAL   A 1 78  ? 140.655 143.323 186.806 1.00 77.39  ? 78   VAL   N CG2 1 
ATOM   566  N  N   . TYR   A 1 79  ? 140.824 140.039 186.761 1.00 80.87  ? 79   TYR   N N   1 
ATOM   567  C  CA  . TYR   A 1 79  ? 140.733 139.025 187.799 1.00 80.87  ? 79   TYR   N CA  1 
ATOM   568  C  C   . TYR   A 1 79  ? 141.193 139.609 189.126 1.00 80.87  ? 79   TYR   N C   1 
ATOM   569  O  O   . TYR   A 1 79  ? 142.236 140.269 189.202 1.00 80.87  ? 79   TYR   N O   1 
ATOM   570  C  CB  . TYR   A 1 79  ? 141.583 137.788 187.467 1.00 80.87  ? 79   TYR   N CB  1 
ATOM   571  C  CG  . TYR   A 1 79  ? 141.385 137.217 186.081 1.00 80.87  ? 79   TYR   N CG  1 
ATOM   572  C  CD1 . TYR   A 1 79  ? 140.119 137.130 185.517 1.00 80.87  ? 79   TYR   N CD1 1 
ATOM   573  C  CD2 . TYR   A 1 79  ? 142.466 136.769 185.336 1.00 80.87  ? 79   TYR   N CD2 1 
ATOM   574  C  CE1 . TYR   A 1 79  ? 139.935 136.611 184.255 1.00 80.87  ? 79   TYR   N CE1 1 
ATOM   575  C  CE2 . TYR   A 1 79  ? 142.292 136.248 184.072 1.00 80.87  ? 79   TYR   N CE2 1 
ATOM   576  C  CZ  . TYR   A 1 79  ? 141.024 136.173 183.536 1.00 80.87  ? 79   TYR   N CZ  1 
ATOM   577  O  OH  . TYR   A 1 79  ? 140.843 135.654 182.275 1.00 80.87  ? 79   TYR   N OH  1 
ATOM   578  N  N   . LEU   A 1 80  ? 140.411 139.351 190.168 1.00 78.47  ? 80   LEU   N N   1 
ATOM   579  C  CA  . LEU   A 1 80  ? 140.743 139.739 191.531 1.00 78.47  ? 80   LEU   N CA  1 
ATOM   580  C  C   . LEU   A 1 80  ? 140.986 138.474 192.337 1.00 78.47  ? 80   LEU   N C   1 
ATOM   581  O  O   . LEU   A 1 80  ? 140.095 137.625 192.445 1.00 78.47  ? 80   LEU   N O   1 
ATOM   582  C  CB  . LEU   A 1 80  ? 139.622 140.564 192.166 1.00 78.47  ? 80   LEU   N CB  1 
ATOM   583  C  CG  . LEU   A 1 80  ? 139.925 141.270 193.494 1.00 78.47  ? 80   LEU   N CG  1 
ATOM   584  C  CD1 . LEU   A 1 80  ? 141.286 141.936 193.493 1.00 78.47  ? 80   LEU   N CD1 1 
ATOM   585  C  CD2 . LEU   A 1 80  ? 138.844 142.263 193.865 1.00 78.47  ? 80   LEU   N CD2 1 
ATOM   586  N  N   . GLN   A 1 81  ? 142.185 138.347 192.891 1.00 84.96  ? 81   GLN   N N   1 
ATOM   587  C  CA  . GLN   A 1 81  ? 142.522 137.263 193.798 1.00 84.96  ? 81   GLN   N CA  1 
ATOM   588  C  C   . GLN   A 1 81  ? 142.562 137.825 195.209 1.00 84.96  ? 81   GLN   N C   1 
ATOM   589  O  O   . GLN   A 1 81  ? 143.232 138.832 195.463 1.00 84.96  ? 81   GLN   N O   1 
ATOM   590  C  CB  . GLN   A 1 81  ? 143.870 136.637 193.427 1.00 84.96  ? 81   GLN   N CB  1 
ATOM   591  C  CG  . GLN   A 1 81  ? 144.687 136.071 194.589 1.00 84.96  ? 81   GLN   N CG  1 
ATOM   592  C  CD  . GLN   A 1 81  ? 144.032 134.875 195.257 1.00 84.96  ? 81   GLN   N CD  1 
ATOM   593  O  OE1 . GLN   A 1 81  ? 143.354 134.081 194.610 1.00 84.96  ? 81   GLN   N OE1 1 
ATOM   594  N  NE2 . GLN   A 1 81  ? 144.240 134.741 196.560 1.00 84.96  ? 81   GLN   N NE2 1 
ATOM   595  N  N   . MET   A 1 82  ? 141.830 137.192 196.118 1.00 87.20  ? 82   MET   N N   1 
ATOM   596  C  CA  . MET   A 1 82  ? 141.919 137.564 197.521 1.00 87.20  ? 82   MET   N CA  1 
ATOM   597  C  C   . MET   A 1 82  ? 142.129 136.320 198.367 1.00 87.20  ? 82   MET   N C   1 
ATOM   598  O  O   . MET   A 1 82  ? 141.660 135.232 198.030 1.00 87.20  ? 82   MET   N O   1 
ATOM   599  C  CB  . MET   A 1 82  ? 140.685 138.343 197.992 1.00 87.20  ? 82   MET   N CB  1 
ATOM   600  C  CG  . MET   A 1 82  ? 139.420 137.531 198.112 1.00 87.20  ? 82   MET   N CG  1 
ATOM   601  S  SD  . MET   A 1 82  ? 138.558 137.410 196.542 1.00 87.20  ? 82   MET   N SD  1 
ATOM   602  C  CE  . MET   A 1 82  ? 137.921 139.067 196.389 1.00 87.20  ? 82   MET   N CE  1 
ATOM   603  N  N   . ASN   A 1 83  ? 142.877 136.490 199.454 1.00 93.56  ? 83   ASN   N N   1 
ATOM   604  C  CA  . ASN   A 1 83  ? 143.182 135.390 200.354 1.00 93.56  ? 83   ASN   N CA  1 
ATOM   605  C  C   . ASN   A 1 83  ? 143.232 135.925 201.775 1.00 93.56  ? 83   ASN   N C   1 
ATOM   606  O  O   . ASN   A 1 83  ? 143.409 137.126 201.998 1.00 93.56  ? 83   ASN   N O   1 
ATOM   607  C  CB  . ASN   A 1 83  ? 144.503 134.704 199.990 1.00 93.56  ? 83   ASN   N CB  1 
ATOM   608  C  CG  . ASN   A 1 83  ? 145.647 135.685 199.831 1.00 93.56  ? 83   ASN   N CG  1 
ATOM   609  O  OD1 . ASN   A 1 83  ? 145.441 136.896 199.806 1.00 93.56  ? 83   ASN   N OD1 1 
ATOM   610  N  ND2 . ASN   A 1 83  ? 146.863 135.163 199.726 1.00 93.56  ? 83   ASN   N ND2 1 
ATOM   611  N  N   . SER   A 1 84  ? 143.090 135.002 202.729 1.00 100.17 ? 84   SER   N N   1 
ATOM   612  C  CA  . SER   A 1 84  ? 142.959 135.298 204.157 1.00 100.17 ? 84   SER   N CA  1 
ATOM   613  C  C   . SER   A 1 84  ? 141.813 136.280 204.397 1.00 100.17 ? 84   SER   N C   1 
ATOM   614  O  O   . SER   A 1 84  ? 141.990 137.384 204.913 1.00 100.17 ? 84   SER   N O   1 
ATOM   615  C  CB  . SER   A 1 84  ? 144.277 135.814 204.747 1.00 100.17 ? 84   SER   N CB  1 
ATOM   616  O  OG  . SER   A 1 84  ? 144.504 137.165 204.389 1.00 100.17 ? 84   SER   N OG  1 
ATOM   617  N  N   . LEU   A 1 85  ? 140.623 135.851 203.989 1.00 98.81  ? 85   LEU   N N   1 
ATOM   618  C  CA  . LEU   A 1 85  ? 139.440 136.689 204.091 1.00 98.81  ? 85   LEU   N CA  1 
ATOM   619  C  C   . LEU   A 1 85  ? 139.012 136.860 205.545 1.00 98.81  ? 85   LEU   N C   1 
ATOM   620  O  O   . LEU   A 1 85  ? 139.157 135.959 206.374 1.00 98.81  ? 85   LEU   N O   1 
ATOM   621  C  CB  . LEU   A 1 85  ? 138.299 136.092 203.271 1.00 98.81  ? 85   LEU   N CB  1 
ATOM   622  C  CG  . LEU   A 1 85  ? 138.314 136.429 201.780 1.00 98.81  ? 85   LEU   N CG  1 
ATOM   623  C  CD1 . LEU   A 1 85  ? 137.218 135.678 201.045 1.00 98.81  ? 85   LEU   N CD1 1 
ATOM   624  C  CD2 . LEU   A 1 85  ? 138.163 137.925 201.580 1.00 98.81  ? 85   LEU   N CD2 1 
ATOM   625  N  N   . LYS   A 1 86  ? 138.480 138.038 205.843 1.00 99.08  ? 86   LYS   N N   1 
ATOM   626  C  CA  . LYS   A 1 86  ? 138.051 138.464 207.163 1.00 99.08  ? 86   LYS   N CA  1 
ATOM   627  C  C   . LYS   A 1 86  ? 136.581 138.850 207.085 1.00 99.08  ? 86   LYS   N C   1 
ATOM   628  O  O   . LYS   A 1 86  ? 136.143 139.378 206.059 1.00 99.08  ? 86   LYS   N O   1 
ATOM   629  C  CB  . LYS   A 1 86  ? 138.897 139.657 207.638 1.00 99.08  ? 86   LYS   N CB  1 
ATOM   630  C  CG  . LYS   A 1 86  ? 140.033 139.304 208.589 1.00 99.08  ? 86   LYS   N CG  1 
ATOM   631  C  CD  . LYS   A 1 86  ? 141.081 138.429 207.920 1.00 99.08  ? 86   LYS   N CD  1 
ATOM   632  C  CE  . LYS   A 1 86  ? 142.457 138.652 208.528 1.00 99.08  ? 86   LYS   N CE  1 
ATOM   633  N  NZ  . LYS   A 1 86  ? 143.543 138.039 207.714 1.00 99.08  ? 86   LYS   N NZ  1 
ATOM   634  N  N   . PRO   A 1 87  ? 135.792 138.622 208.139 1.00 101.61 ? 87   PRO   N N   1 
ATOM   635  C  CA  . PRO   A 1 87  ? 134.339 138.717 207.999 1.00 101.61 ? 87   PRO   N CA  1 
ATOM   636  C  C   . PRO   A 1 87  ? 133.773 140.128 207.917 1.00 101.61 ? 87   PRO   N C   1 
ATOM   637  O  O   . PRO   A 1 87  ? 132.549 140.278 207.970 1.00 101.61 ? 87   PRO   N O   1 
ATOM   638  C  CB  . PRO   A 1 87  ? 133.847 137.971 209.252 1.00 101.61 ? 87   PRO   N CB  1 
ATOM   639  C  CG  . PRO   A 1 87  ? 135.073 137.949 210.207 1.00 101.61 ? 87   PRO   N CG  1 
ATOM   640  C  CD  . PRO   A 1 87  ? 136.099 138.818 209.568 1.00 101.61 ? 87   PRO   N CD  1 
ATOM   641  N  N   . GLU   A 1 88  ? 134.595 141.168 207.777 1.00 101.94 ? 88   GLU   N N   1 
ATOM   642  C  CA  . GLU   A 1 88  ? 134.101 142.479 207.382 1.00 101.94 ? 88   GLU   N CA  1 
ATOM   643  C  C   . GLU   A 1 88  ? 134.131 142.666 205.870 1.00 101.94 ? 88   GLU   N C   1 
ATOM   644  O  O   . GLU   A 1 88  ? 133.810 143.754 205.382 1.00 101.94 ? 88   GLU   N O   1 
ATOM   645  C  CB  . GLU   A 1 88  ? 134.902 143.598 208.061 1.00 101.94 ? 88   GLU   N CB  1 
ATOM   646  C  CG  . GLU   A 1 88  ? 136.346 143.755 207.591 1.00 101.94 ? 88   GLU   N CG  1 
ATOM   647  C  CD  . GLU   A 1 88  ? 137.321 142.838 208.306 1.00 101.94 ? 88   GLU   N CD  1 
ATOM   648  O  OE1 . GLU   A 1 88  ? 136.877 141.873 208.956 1.00 101.94 ? 88   GLU   N OE1 1 
ATOM   649  O  OE2 . GLU   A 1 88  ? 138.542 143.085 208.216 1.00 101.94 ? 88   GLU   N OE2 1 
ATOM   650  N  N   . ASP   A 1 89  ? 134.509 141.632 205.123 1.00 94.88  ? 89   ASP   N N   1 
ATOM   651  C  CA  . ASP   A 1 89  ? 134.554 141.688 203.670 1.00 94.88  ? 89   ASP   N CA  1 
ATOM   652  C  C   . ASP   A 1 89  ? 133.284 141.169 203.013 1.00 94.88  ? 89   ASP   N C   1 
ATOM   653  O  O   . ASP   A 1 89  ? 133.218 141.134 201.780 1.00 94.88  ? 89   ASP   N O   1 
ATOM   654  C  CB  . ASP   A 1 89  ? 135.758 140.901 203.146 1.00 94.88  ? 89   ASP   N CB  1 
ATOM   655  C  CG  . ASP   A 1 89  ? 137.050 141.309 203.816 1.00 94.88  ? 89   ASP   N CG  1 
ATOM   656  O  OD1 . ASP   A 1 89  ? 137.097 142.421 204.378 1.00 94.88  ? 89   ASP   N OD1 1 
ATOM   657  O  OD2 . ASP   A 1 89  ? 138.017 140.521 203.781 1.00 94.88  ? 89   ASP   N OD2 1 
ATOM   658  N  N   . THR   A 1 90  ? 132.285 140.765 203.795 1.00 95.24  ? 90   THR   N N   1 
ATOM   659  C  CA  . THR   A 1 90  ? 131.003 140.327 203.248 1.00 95.24  ? 90   THR   N CA  1 
ATOM   660  C  C   . THR   A 1 90  ? 130.321 141.533 202.621 1.00 95.24  ? 90   THR   N C   1 
ATOM   661  O  O   . THR   A 1 90  ? 129.784 142.392 203.323 1.00 95.24  ? 90   THR   N O   1 
ATOM   662  C  CB  . THR   A 1 90  ? 130.128 139.718 204.337 1.00 95.24  ? 90   THR   N CB  1 
ATOM   663  O  OG1 . THR   A 1 90  ? 129.614 140.762 205.173 1.00 95.24  ? 90   THR   N OG1 1 
ATOM   664  C  CG2 . THR   A 1 90  ? 130.931 138.761 205.190 1.00 95.24  ? 90   THR   N CG2 1 
ATOM   665  N  N   . ALA   A 1 91  ? 130.336 141.603 201.295 1.00 86.19  ? 91   ALA   N N   1 
ATOM   666  C  CA  . ALA   A 1 91  ? 129.912 142.815 200.613 1.00 86.19  ? 91   ALA   N CA  1 
ATOM   667  C  C   . ALA   A 1 91  ? 129.447 142.461 199.211 1.00 86.19  ? 91   ALA   N C   1 
ATOM   668  O  O   . ALA   A 1 91  ? 129.704 141.367 198.703 1.00 86.19  ? 91   ALA   N O   1 
ATOM   669  C  CB  . ALA   A 1 91  ? 131.045 143.843 200.568 1.00 86.19  ? 91   ALA   N CB  1 
ATOM   670  N  N   . VAL   A 1 92  ? 128.746 143.400 198.591 1.00 80.13  ? 92   VAL   N N   1 
ATOM   671  C  CA  . VAL   A 1 92  ? 128.391 143.283 197.185 1.00 80.13  ? 92   VAL   N CA  1 
ATOM   672  C  C   . VAL   A 1 92  ? 129.499 143.946 196.381 1.00 80.13  ? 92   VAL   N C   1 
ATOM   673  O  O   . VAL   A 1 92  ? 129.782 145.136 196.563 1.00 80.13  ? 92   VAL   N O   1 
ATOM   674  C  CB  . VAL   A 1 92  ? 127.028 143.923 196.894 1.00 80.13  ? 92   VAL   N CB  1 
ATOM   675  C  CG1 . VAL   A 1 92  ? 126.647 143.706 195.443 1.00 80.13  ? 92   VAL   N CG1 1 
ATOM   676  C  CG2 . VAL   A 1 92  ? 125.971 143.349 197.818 1.00 80.13  ? 92   VAL   N CG2 1 
ATOM   677  N  N   . TYR   A 1 93  ? 130.146 143.174 195.515 1.00 76.37  ? 93   TYR   N N   1 
ATOM   678  C  CA  . TYR   A 1 93  ? 131.290 143.641 194.748 1.00 76.37  ? 93   TYR   N CA  1 
ATOM   679  C  C   . TYR   A 1 93  ? 130.838 144.045 193.354 1.00 76.37  ? 93   TYR   N C   1 
ATOM   680  O  O   . TYR   A 1 93  ? 130.127 143.292 192.682 1.00 76.37  ? 93   TYR   N O   1 
ATOM   681  C  CB  . TYR   A 1 93  ? 132.364 142.560 194.661 1.00 76.37  ? 93   TYR   N CB  1 
ATOM   682  C  CG  . TYR   A 1 93  ? 133.324 142.559 195.824 1.00 76.37  ? 93   TYR   N CG  1 
ATOM   683  C  CD1 . TYR   A 1 93  ? 132.992 141.946 197.021 1.00 76.37  ? 93   TYR   N CD1 1 
ATOM   684  C  CD2 . TYR   A 1 93  ? 134.564 143.168 195.723 1.00 76.37  ? 93   TYR   N CD2 1 
ATOM   685  C  CE1 . TYR   A 1 93  ? 133.866 141.941 198.083 1.00 76.37  ? 93   TYR   N CE1 1 
ATOM   686  C  CE2 . TYR   A 1 93  ? 135.446 143.167 196.780 1.00 76.37  ? 93   TYR   N CE2 1 
ATOM   687  C  CZ  . TYR   A 1 93  ? 135.091 142.554 197.957 1.00 76.37  ? 93   TYR   N CZ  1 
ATOM   688  O  OH  . TYR   A 1 93  ? 135.967 142.552 199.016 1.00 76.37  ? 93   TYR   N OH  1 
ATOM   689  N  N   . TYR   A 1 94  ? 131.254 145.231 192.929 1.00 79.03  ? 94   TYR   N N   1 
ATOM   690  C  CA  . TYR   A 1 94  ? 130.943 145.757 191.612 1.00 79.03  ? 94   TYR   N CA  1 
ATOM   691  C  C   . TYR   A 1 94  ? 132.222 145.871 190.797 1.00 79.03  ? 94   TYR   N C   1 
ATOM   692  O  O   . TYR   A 1 94  ? 133.311 146.084 191.338 1.00 79.03  ? 94   TYR   N O   1 
ATOM   693  C  CB  . TYR   A 1 94  ? 130.274 147.137 191.677 1.00 79.03  ? 94   TYR   N CB  1 
ATOM   694  C  CG  . TYR   A 1 94  ? 128.889 147.197 192.290 1.00 79.03  ? 94   TYR   N CG  1 
ATOM   695  C  CD1 . TYR   A 1 94  ? 127.807 147.646 191.542 1.00 79.03  ? 94   TYR   N CD1 1 
ATOM   696  C  CD2 . TYR   A 1 94  ? 128.672 146.880 193.625 1.00 79.03  ? 94   TYR   N CD2 1 
ATOM   697  C  CE1 . TYR   A 1 94  ? 126.544 147.725 192.090 1.00 79.03  ? 94   TYR   N CE1 1 
ATOM   698  C  CE2 . TYR   A 1 94  ? 127.414 146.959 194.182 1.00 79.03  ? 94   TYR   N CE2 1 
ATOM   699  C  CZ  . TYR   A 1 94  ? 126.355 147.382 193.412 1.00 79.03  ? 94   TYR   N CZ  1 
ATOM   700  O  OH  . TYR   A 1 94  ? 125.100 147.462 193.968 1.00 79.03  ? 94   TYR   N OH  1 
ATOM   701  N  N   . CYS   A 1 95  ? 132.073 145.733 189.486 1.00 77.54  ? 95   CYS   N N   1 
ATOM   702  C  CA  . CYS   A 1 95  ? 133.165 145.911 188.543 1.00 77.54  ? 95   CYS   N CA  1 
ATOM   703  C  C   . CYS   A 1 95  ? 132.972 147.245 187.836 1.00 77.54  ? 95   CYS   N C   1 
ATOM   704  O  O   . CYS   A 1 95  ? 131.955 147.453 187.166 1.00 77.54  ? 95   CYS   N O   1 
ATOM   705  C  CB  . CYS   A 1 95  ? 133.194 144.758 187.541 1.00 77.54  ? 95   CYS   N CB  1 
ATOM   706  S  SG  . CYS   A 1 95  ? 134.534 144.792 186.337 1.00 77.54  ? 95   CYS   N SG  1 
ATOM   707  N  N   . ALA   A 1 96  ? 133.934 148.149 187.993 1.00 70.28  ? 96   ALA   N N   1 
ATOM   708  C  CA  . ALA   A 1 96  ? 133.886 149.462 187.373 1.00 70.28  ? 96   ALA   N CA  1 
ATOM   709  C  C   . ALA   A 1 96  ? 134.954 149.555 186.298 1.00 70.28  ? 96   ALA   N C   1 
ATOM   710  O  O   . ALA   A 1 96  ? 136.060 149.034 186.460 1.00 70.28  ? 96   ALA   N O   1 
ATOM   711  C  CB  . ALA   A 1 96  ? 134.091 150.570 188.402 1.00 70.28  ? 96   ALA   N CB  1 
ATOM   712  N  N   . ALA   A 1 97  ? 134.618 150.215 185.199 1.00 68.44  ? 97   ALA   N N   1 
ATOM   713  C  CA  . ALA   A 1 97  ? 135.510 150.310 184.050 1.00 68.44  ? 97   ALA   N CA  1 
ATOM   714  C  C   . ALA   A 1 97  ? 135.424 151.727 183.509 1.00 68.44  ? 97   ALA   N C   1 
ATOM   715  O  O   . ALA   A 1 97  ? 134.361 152.146 183.049 1.00 68.44  ? 97   ALA   N O   1 
ATOM   716  C  CB  . ALA   A 1 97  ? 135.127 149.289 182.984 1.00 68.44  ? 97   ALA   N CB  1 
ATOM   717  N  N   . GLU   A 1 98  ? 136.524 152.468 183.569 1.00 69.18  ? 98   GLU   N N   1 
ATOM   718  C  CA  . GLU   A 1 98  ? 136.548 153.855 183.133 1.00 69.18  ? 98   GLU   N CA  1 
ATOM   719  C  C   . GLU   A 1 98  ? 137.452 154.003 181.920 1.00 69.18  ? 98   GLU   N C   1 
ATOM   720  O  O   . GLU   A 1 98  ? 138.585 153.508 181.917 1.00 69.18  ? 98   GLU   N O   1 
ATOM   721  C  CB  . GLU   A 1 98  ? 137.027 154.780 184.252 1.00 69.18  ? 98   GLU   N CB  1 
ATOM   722  C  CG  . GLU   A 1 98  ? 136.373 154.523 185.594 1.00 69.18  ? 98   GLU   N CG  1 
ATOM   723  C  CD  . GLU   A 1 98  ? 137.271 154.895 186.755 1.00 69.18  ? 98   GLU   N CD  1 
ATOM   724  O  OE1 . GLU   A 1 98  ? 138.324 155.520 186.512 1.00 69.18  ? 98   GLU   N OE1 1 
ATOM   725  O  OE2 . GLU   A 1 98  ? 136.927 154.562 187.909 1.00 69.18  ? 98   GLU   N OE2 1 
ATOM   726  N  N   . VAL   A 1 99  ? 136.942 154.676 180.898 1.00 69.06  ? 99   VAL   N N   1 
ATOM   727  C  CA  . VAL   A 1 99  ? 137.757 155.175 179.798 1.00 69.06  ? 99   VAL   N CA  1 
ATOM   728  C  C   . VAL   A 1 99  ? 138.003 156.660 180.025 1.00 69.06  ? 99   VAL   N C   1 
ATOM   729  O  O   . VAL   A 1 99  ? 137.089 157.416 180.379 1.00 69.06  ? 99   VAL   N O   1 
ATOM   730  C  CB  . VAL   A 1 99  ? 137.113 154.893 178.422 1.00 69.06  ? 99   VAL   N CB  1 
ATOM   731  C  CG1 . VAL   A 1 99  ? 136.986 153.412 178.209 1.00 69.06  ? 99   VAL   N CG1 1 
ATOM   732  C  CG2 . VAL   A 1 99  ? 135.738 155.520 178.287 1.00 69.06  ? 99   VAL   N CG2 1 
ATOM   733  N  N   . LEU   A 1 100 ? 139.255 157.073 179.890 1.00 67.66  ? 100  LEU   N N   1 
ATOM   734  C  CA  . LEU   A 1 100 ? 139.641 158.450 180.151 1.00 67.66  ? 100  LEU   N CA  1 
ATOM   735  C  C   . LEU   A 1 100 ? 140.311 159.042 178.922 1.00 67.66  ? 100  LEU   N C   1 
ATOM   736  O  O   . LEU   A 1 100 ? 141.078 158.367 178.230 1.00 67.66  ? 100  LEU   N O   1 
ATOM   737  C  CB  . LEU   A 1 100 ? 140.553 158.559 181.386 1.00 67.66  ? 100  LEU   N CB  1 
ATOM   738  C  CG  . LEU   A 1 100 ? 142.012 158.103 181.409 1.00 67.66  ? 100  LEU   N CG  1 
ATOM   739  C  CD1 . LEU   A 1 100 ? 142.704 158.693 182.618 1.00 67.66  ? 100  LEU   N CD1 1 
ATOM   740  C  CD2 . LEU   A 1 100 ? 142.098 156.604 181.483 1.00 67.66  ? 100  LEU   N CD2 1 
ATOM   741  N  N   . ASP   A 1 101 ? 140.000 160.306 178.655 1.00 67.53  ? 101  ASP   N N   1 
ATOM   742  C  CA  . ASP   A 1 101 ? 140.439 160.977 177.441 1.00 67.53  ? 101  ASP   N CA  1 
ATOM   743  C  C   . ASP   A 1 101 ? 141.836 161.553 177.627 1.00 67.53  ? 101  ASP   N C   1 
ATOM   744  O  O   . ASP   A 1 101 ? 142.137 162.154 178.661 1.00 67.53  ? 101  ASP   N O   1 
ATOM   745  C  CB  . ASP   A 1 101 ? 139.445 162.077 177.080 1.00 67.53  ? 101  ASP   N CB  1 
ATOM   746  C  CG  . ASP   A 1 101 ? 139.752 162.730 175.758 1.00 67.53  ? 101  ASP   N CG  1 
ATOM   747  O  OD1 . ASP   A 1 101 ? 139.507 162.104 174.706 1.00 67.53  ? 101  ASP   N OD1 1 
ATOM   748  O  OD2 . ASP   A 1 101 ? 140.228 163.880 175.770 1.00 67.53  ? 101  ASP   N OD2 1 
ATOM   749  N  N   . TYR   A 1 102 ? 142.694 161.361 176.622 1.00 67.92  ? 102  TYR   N N   1 
ATOM   750  C  CA  . TYR   A 1 102 ? 144.065 161.852 176.713 1.00 67.92  ? 102  TYR   N CA  1 
ATOM   751  C  C   . TYR   A 1 102 ? 144.147 163.362 176.539 1.00 67.92  ? 102  TYR   N C   1 
ATOM   752  O  O   . TYR   A 1 102 ? 145.030 164.001 177.120 1.00 67.92  ? 102  TYR   N O   1 
ATOM   753  C  CB  . TYR   A 1 102 ? 144.943 161.159 175.672 1.00 67.92  ? 102  TYR   N CB  1 
ATOM   754  C  CG  . TYR   A 1 102 ? 146.404 161.118 176.049 1.00 67.92  ? 102  TYR   N CG  1 
ATOM   755  C  CD1 . TYR   A 1 102 ? 146.915 160.077 176.808 1.00 67.92  ? 102  TYR   N CD1 1 
ATOM   756  C  CD2 . TYR   A 1 102 ? 147.273 162.122 175.646 1.00 67.92  ? 102  TYR   N CD2 1 
ATOM   757  C  CE1 . TYR   A 1 102 ? 148.251 160.036 177.158 1.00 67.92  ? 102  TYR   N CE1 1 
ATOM   758  C  CE2 . TYR   A 1 102 ? 148.611 162.090 175.990 1.00 67.92  ? 102  TYR   N CE2 1 
ATOM   759  C  CZ  . TYR   A 1 102 ? 149.093 161.044 176.747 1.00 67.92  ? 102  TYR   N CZ  1 
ATOM   760  O  OH  . TYR   A 1 102 ? 150.424 161.003 177.095 1.00 67.92  ? 102  TYR   N OH  1 
ATOM   761  N  N   . THR   A 1 103 ? 143.255 163.945 175.738 1.00 63.00  ? 103  THR   N N   1 
ATOM   762  C  CA  . THR   A 1 103 ? 143.328 165.376 175.469 1.00 63.00  ? 103  THR   N CA  1 
ATOM   763  C  C   . THR   A 1 103 ? 142.939 166.194 176.693 1.00 63.00  ? 103  THR   N C   1 
ATOM   764  O  O   . THR   A 1 103 ? 143.553 167.228 176.976 1.00 63.00  ? 103  THR   N O   1 
ATOM   765  C  CB  . THR   A 1 103 ? 142.433 165.731 174.285 1.00 63.00  ? 103  THR   N CB  1 
ATOM   766  O  OG1 . THR   A 1 103 ? 141.078 165.843 174.735 1.00 63.00  ? 103  THR   N OG1 1 
ATOM   767  C  CG2 . THR   A 1 103 ? 142.509 164.652 173.222 1.00 63.00  ? 103  THR   N CG2 1 
ATOM   768  N  N   . PHE   A 1 104 ? 141.928 165.748 177.432 1.00 61.11  ? 104  PHE   N N   1 
ATOM   769  C  CA  . PHE   A 1 104 ? 141.422 166.471 178.590 1.00 61.11  ? 104  PHE   N CA  1 
ATOM   770  C  C   . PHE   A 1 104 ? 141.355 165.510 179.765 1.00 61.11  ? 104  PHE   N C   1 
ATOM   771  O  O   . PHE   A 1 104 ? 140.605 164.530 179.724 1.00 61.11  ? 104  PHE   N O   1 
ATOM   772  C  CB  . PHE   A 1 104 ? 140.049 167.079 178.287 1.00 61.11  ? 104  PHE   N CB  1 
ATOM   773  C  CG  . PHE   A 1 104 ? 139.585 168.080 179.303 1.00 61.11  ? 104  PHE   N CG  1 
ATOM   774  C  CD1 . PHE   A 1 104 ? 140.495 168.804 180.049 1.00 61.11  ? 104  PHE   N CD1 1 
ATOM   775  C  CD2 . PHE   A 1 104 ? 138.238 168.334 179.471 1.00 61.11  ? 104  PHE   N CD2 1 
ATOM   776  C  CE1 . PHE   A 1 104 ? 140.066 169.729 180.972 1.00 61.11  ? 104  PHE   N CE1 1 
ATOM   777  C  CE2 . PHE   A 1 104 ? 137.805 169.261 180.389 1.00 61.11  ? 104  PHE   N CE2 1 
ATOM   778  C  CZ  . PHE   A 1 104 ? 138.720 169.959 181.138 1.00 61.11  ? 104  PHE   N CZ  1 
ATOM   779  N  N   . ALA   A 1 105 ? 142.136 165.793 180.809 1.00 61.83  ? 105  ALA   N N   1 
ATOM   780  C  CA  . ALA   A 1 105 ? 142.250 164.874 181.934 1.00 61.83  ? 105  ALA   N CA  1 
ATOM   781  C  C   . ALA   A 1 105 ? 141.001 164.846 182.804 1.00 61.83  ? 105  ALA   N C   1 
ATOM   782  O  O   . ALA   A 1 105 ? 140.821 163.899 183.577 1.00 61.83  ? 105  ALA   N O   1 
ATOM   783  C  CB  . ALA   A 1 105 ? 143.462 165.240 182.787 1.00 61.83  ? 105  ALA   N CB  1 
ATOM   784  N  N   . TYR   A 1 106 ? 140.145 165.860 182.706 1.00 59.19  ? 106  TYR   N N   1 
ATOM   785  C  CA  . TYR   A 1 106 ? 138.926 165.891 183.504 1.00 59.19  ? 106  TYR   N CA  1 
ATOM   786  C  C   . TYR   A 1 106 ? 137.869 164.930 182.971 1.00 59.19  ? 106  TYR   N C   1 
ATOM   787  O  O   . TYR   A 1 106 ? 137.061 164.414 183.750 1.00 59.19  ? 106  TYR   N O   1 
ATOM   788  C  CB  . TYR   A 1 106 ? 138.386 167.320 183.552 1.00 59.19  ? 106  TYR   N CB  1 
ATOM   789  C  CG  . TYR   A 1 106 ? 137.274 167.547 184.545 1.00 59.19  ? 106  TYR   N CG  1 
ATOM   790  C  CD1 . TYR   A 1 106 ? 137.310 166.969 185.804 1.00 59.19  ? 106  TYR   N CD1 1 
ATOM   791  C  CD2 . TYR   A 1 106 ? 136.194 168.357 184.225 1.00 59.19  ? 106  TYR   N CD2 1 
ATOM   792  C  CE1 . TYR   A 1 106 ? 136.291 167.181 186.713 1.00 59.19  ? 106  TYR   N CE1 1 
ATOM   793  C  CE2 . TYR   A 1 106 ? 135.173 168.575 185.123 1.00 59.19  ? 106  TYR   N CE2 1 
ATOM   794  C  CZ  . TYR   A 1 106 ? 135.226 167.986 186.365 1.00 59.19  ? 106  TYR   N CZ  1 
ATOM   795  O  OH  . TYR   A 1 106 ? 134.208 168.204 187.261 1.00 59.19  ? 106  TYR   N OH  1 
ATOM   796  N  N   . LEU   A 1 107 ? 137.862 164.675 181.664 1.00 63.81  ? 107  LEU   N N   1 
ATOM   797  C  CA  . LEU   A 1 107 ? 136.869 163.788 181.072 1.00 63.81  ? 107  LEU   N CA  1 
ATOM   798  C  C   . LEU   A 1 107 ? 137.125 162.334 181.440 1.00 63.81  ? 107  LEU   N C   1 
ATOM   799  O  O   . LEU   A 1 107 ? 138.269 161.872 181.462 1.00 63.81  ? 107  LEU   N O   1 
ATOM   800  C  CB  . LEU   A 1 107 ? 136.863 163.928 179.553 1.00 63.81  ? 107  LEU   N CB  1 
ATOM   801  C  CG  . LEU   A 1 107 ? 136.406 165.263 178.989 1.00 63.81  ? 107  LEU   N CG  1 
ATOM   802  C  CD1 . LEU   A 1 107 ? 136.591 165.288 177.487 1.00 63.81  ? 107  LEU   N CD1 1 
ATOM   803  C  CD2 . LEU   A 1 107 ? 134.955 165.468 179.341 1.00 63.81  ? 107  LEU   N CD2 1 
ATOM   804  N  N   . TYR   A 1 108 ? 136.039 161.611 181.702 1.00 62.10  ? 108  TYR   N N   1 
ATOM   805  C  CA  . TYR   A 1 108 ? 136.073 160.191 182.015 1.00 62.10  ? 108  TYR   N CA  1 
ATOM   806  C  C   . TYR   A 1 108 ? 134.666 159.632 181.873 1.00 62.10  ? 108  TYR   N C   1 
ATOM   807  O  O   . TYR   A 1 108 ? 133.679 160.322 182.138 1.00 62.10  ? 108  TYR   N O   1 
ATOM   808  C  CB  . TYR   A 1 108 ? 136.613 159.928 183.427 1.00 62.10  ? 108  TYR   N CB  1 
ATOM   809  C  CG  . TYR   A 1 108 ? 135.634 160.244 184.532 1.00 62.10  ? 108  TYR   N CG  1 
ATOM   810  C  CD1 . TYR   A 1 108 ? 135.316 161.558 184.849 1.00 62.10  ? 108  TYR   N CD1 1 
ATOM   811  C  CD2 . TYR   A 1 108 ? 135.028 159.230 185.260 1.00 62.10  ? 108  TYR   N CD2 1 
ATOM   812  C  CE1 . TYR   A 1 108 ? 134.422 161.853 185.855 1.00 62.10  ? 108  TYR   N CE1 1 
ATOM   813  C  CE2 . TYR   A 1 108 ? 134.131 159.516 186.269 1.00 62.10  ? 108  TYR   N CE2 1 
ATOM   814  C  CZ  . TYR   A 1 108 ? 133.833 160.829 186.561 1.00 62.10  ? 108  TYR   N CZ  1 
ATOM   815  O  OH  . TYR   A 1 108 ? 132.943 161.118 187.567 1.00 62.10  ? 108  TYR   N OH  1 
ATOM   816  N  N   . HIS   A 1 109 ? 134.586 158.378 181.440 1.00 70.71  ? 109  HIS   N N   1 
ATOM   817  C  CA  . HIS   A 1 109 ? 133.325 157.657 181.336 1.00 70.71  ? 109  HIS   N CA  1 
ATOM   818  C  C   . HIS   A 1 109 ? 133.457 156.378 182.140 1.00 70.71  ? 109  HIS   N C   1 
ATOM   819  O  O   . HIS   A 1 109 ? 134.355 155.572 181.878 1.00 70.71  ? 109  HIS   N O   1 
ATOM   820  C  CB  . HIS   A 1 109 ? 132.979 157.340 179.879 1.00 70.71  ? 109  HIS   N CB  1 
ATOM   821  C  CG  . HIS   A 1 109 ? 132.177 158.403 179.199 1.00 70.71  ? 109  HIS   N CG  1 
ATOM   822  N  ND1 . HIS   A 1 109 ? 132.735 159.572 178.732 1.00 70.71  ? 109  HIS   N ND1 1 
ATOM   823  C  CD2 . HIS   A 1 109 ? 130.859 158.469 178.898 1.00 70.71  ? 109  HIS   N CD2 1 
ATOM   824  C  CE1 . HIS   A 1 109 ? 131.795 160.316 178.177 1.00 70.71  ? 109  HIS   N CE1 1 
ATOM   825  N  NE2 . HIS   A 1 109 ? 130.647 159.669 178.265 1.00 70.71  ? 109  HIS   N NE2 1 
ATOM   826  N  N   . ALA   A 1 110 ? 132.569 156.190 183.109 1.00 68.82  ? 110  ALA   N N   1 
ATOM   827  C  CA  . ALA   A 1 110 ? 132.604 155.035 183.992 1.00 68.82  ? 110  ALA   N CA  1 
ATOM   828  C  C   . ALA   A 1 110 ? 131.396 154.148 183.736 1.00 68.82  ? 110  ALA   N C   1 
ATOM   829  O  O   . ALA   A 1 110 ? 130.270 154.635 183.601 1.00 68.82  ? 110  ALA   N O   1 
ATOM   830  C  CB  . ALA   A 1 110 ? 132.638 155.462 185.460 1.00 68.82  ? 110  ALA   N CB  1 
ATOM   831  N  N   . TYR   A 1 111 ? 131.641 152.843 183.667 1.00 69.94  ? 111  TYR   N N   1 
ATOM   832  C  CA  . TYR   A 1 111 ? 130.604 151.851 183.454 1.00 69.94  ? 111  TYR   N CA  1 
ATOM   833  C  C   . TYR   A 1 111 ? 130.679 150.820 184.568 1.00 69.94  ? 111  TYR   N C   1 
ATOM   834  O  O   . TYR   A 1 111 ? 131.744 150.587 185.145 1.00 69.94  ? 111  TYR   N O   1 
ATOM   835  C  CB  . TYR   A 1 111 ? 130.752 151.183 182.091 1.00 69.94  ? 111  TYR   N CB  1 
ATOM   836  C  CG  . TYR   A 1 111 ? 131.004 152.168 180.976 1.00 69.94  ? 111  TYR   N CG  1 
ATOM   837  C  CD1 . TYR   A 1 111 ? 129.977 152.959 180.481 1.00 69.94  ? 111  TYR   N CD1 1 
ATOM   838  C  CD2 . TYR   A 1 111 ? 132.268 152.315 180.425 1.00 69.94  ? 111  TYR   N CD2 1 
ATOM   839  C  CE1 . TYR   A 1 111 ? 130.201 153.863 179.465 1.00 69.94  ? 111  TYR   N CE1 1 
ATOM   840  C  CE2 . TYR   A 1 111 ? 132.501 153.216 179.408 1.00 69.94  ? 111  TYR   N CE2 1 
ATOM   841  C  CZ  . TYR   A 1 111 ? 131.464 153.987 178.932 1.00 69.94  ? 111  TYR   N CZ  1 
ATOM   842  O  OH  . TYR   A 1 111 ? 131.690 154.888 177.918 1.00 69.94  ? 111  TYR   N OH  1 
ATOM   843  N  N   . TRP   A 1 112 ? 129.540 150.200 184.860 1.00 70.55  ? 112  TRP   N N   1 
ATOM   844  C  CA  . TRP   A 1 112 ? 129.384 149.391 186.057 1.00 70.55  ? 112  TRP   N CA  1 
ATOM   845  C  C   . TRP   A 1 112 ? 128.822 148.022 185.716 1.00 70.55  ? 112  TRP   N C   1 
ATOM   846  O  O   . TRP   A 1 112 ? 128.136 147.844 184.707 1.00 70.55  ? 112  TRP   N O   1 
ATOM   847  C  CB  . TRP   A 1 112 ? 128.460 150.073 187.067 1.00 70.55  ? 112  TRP   N CB  1 
ATOM   848  C  CG  . TRP   A 1 112 ? 128.788 151.503 187.290 1.00 70.55  ? 112  TRP   N CG  1 
ATOM   849  C  CD1 . TRP   A 1 112 ? 128.381 152.568 186.543 1.00 70.55  ? 112  TRP   N CD1 1 
ATOM   850  C  CD2 . TRP   A 1 112 ? 129.596 152.032 188.338 1.00 70.55  ? 112  TRP   N CD2 1 
ATOM   851  N  NE1 . TRP   A 1 112 ? 128.892 153.731 187.061 1.00 70.55  ? 112  TRP   N NE1 1 
ATOM   852  C  CE2 . TRP   A 1 112 ? 129.641 153.427 188.167 1.00 70.55  ? 112  TRP   N CE2 1 
ATOM   853  C  CE3 . TRP   A 1 112 ? 130.286 151.461 189.405 1.00 70.55  ? 112  TRP   N CE3 1 
ATOM   854  C  CZ2 . TRP   A 1 112 ? 130.349 154.257 189.024 1.00 70.55  ? 112  TRP   N CZ2 1 
ATOM   855  C  CZ3 . TRP   A 1 112 ? 130.982 152.283 190.252 1.00 70.55  ? 112  TRP   N CZ3 1 
ATOM   856  C  CH2 . TRP   A 1 112 ? 131.014 153.666 190.060 1.00 70.55  ? 112  TRP   N CH2 1 
ATOM   857  N  N   . GLY   A 1 113 ? 129.126 147.053 186.579 1.00 79.98  ? 113  GLY   N N   1 
ATOM   858  C  CA  . GLY   A 1 113 ? 128.519 145.745 186.518 1.00 79.98  ? 113  GLY   N CA  1 
ATOM   859  C  C   . GLY   A 1 113 ? 127.348 145.625 187.482 1.00 79.98  ? 113  GLY   N C   1 
ATOM   860  O  O   . GLY   A 1 113 ? 126.982 146.559 188.191 1.00 79.98  ? 113  GLY   N O   1 
ATOM   861  N  N   . GLN   A 1 114 ? 126.751 144.434 187.491 1.00 84.87  ? 114  GLN   N N   1 
ATOM   862  C  CA  . GLN   A 1 114 ? 125.617 144.191 188.373 1.00 84.87  ? 114  GLN   N CA  1 
ATOM   863  C  C   . GLN   A 1 114 ? 126.049 143.968 189.814 1.00 84.87  ? 114  GLN   N C   1 
ATOM   864  O  O   . GLN   A 1 114 ? 125.323 144.344 190.740 1.00 84.87  ? 114  GLN   N O   1 
ATOM   865  C  CB  . GLN   A 1 114 ? 124.811 142.993 187.873 1.00 84.87  ? 114  GLN   N CB  1 
ATOM   866  C  CG  . GLN   A 1 114 ? 124.185 143.217 186.514 1.00 84.87  ? 114  GLN   N CG  1 
ATOM   867  C  CD  . GLN   A 1 114 ? 123.127 144.297 186.542 1.00 84.87  ? 114  GLN   N CD  1 
ATOM   868  O  OE1 . GLN   A 1 114 ? 122.357 144.404 187.496 1.00 84.87  ? 114  GLN   N OE1 1 
ATOM   869  N  NE2 . GLN   A 1 114 ? 123.087 145.112 185.496 1.00 84.87  ? 114  GLN   N NE2 1 
ATOM   870  N  N   . GLY   A 1 115 ? 127.214 143.366 190.024 1.00 83.69  ? 115  GLY   N N   1 
ATOM   871  C  CA  . GLY   A 1 115 ? 127.687 143.095 191.364 1.00 83.69  ? 115  GLY   N CA  1 
ATOM   872  C  C   . GLY   A 1 115 ? 127.347 141.696 191.827 1.00 83.69  ? 115  GLY   N C   1 
ATOM   873  O  O   . GLY   A 1 115 ? 126.272 141.174 191.518 1.00 83.69  ? 115  GLY   N O   1 
ATOM   874  N  N   . THR   A 1 116 ? 128.261 141.075 192.564 1.00 84.84  ? 116  THR   N N   1 
ATOM   875  C  CA  . THR   A 1 116 ? 128.064 139.745 193.117 1.00 84.84  ? 116  THR   N CA  1 
ATOM   876  C  C   . THR   A 1 116 ? 128.230 139.803 194.628 1.00 84.84  ? 116  THR   N C   1 
ATOM   877  O  O   . THR   A 1 116 ? 129.093 140.519 195.139 1.00 84.84  ? 116  THR   N O   1 
ATOM   878  C  CB  . THR   A 1 116 ? 129.053 138.738 192.525 1.00 84.84  ? 116  THR   N CB  1 
ATOM   879  O  OG1 . THR   A 1 116 ? 130.393 139.163 192.804 1.00 84.84  ? 116  THR   N OG1 1 
ATOM   880  C  CG2 . THR   A 1 116 ? 128.865 138.619 191.022 1.00 84.84  ? 116  THR   N CG2 1 
ATOM   881  N  N   . GLN   A 1 117 ? 127.393 139.057 195.339 1.00 86.15  ? 117  GLN   N N   1 
ATOM   882  C  CA  . GLN   A 1 117 ? 127.455 139.033 196.791 1.00 86.15  ? 117  GLN   N CA  1 
ATOM   883  C  C   . GLN   A 1 117 ? 128.536 138.061 197.247 1.00 86.15  ? 117  GLN   N C   1 
ATOM   884  O  O   . GLN   A 1 117 ? 128.582 136.913 196.793 1.00 86.15  ? 117  GLN   N O   1 
ATOM   885  C  CB  . GLN   A 1 117 ? 126.096 138.641 197.369 1.00 86.15  ? 117  GLN   N CB  1 
ATOM   886  C  CG  . GLN   A 1 117 ? 126.129 138.208 198.824 1.00 86.15  ? 117  GLN   N CG  1 
ATOM   887  C  CD  . GLN   A 1 117 ? 126.470 139.343 199.767 1.00 86.15  ? 117  GLN   N CD  1 
ATOM   888  O  OE1 . GLN   A 1 117 ? 127.613 139.485 200.195 1.00 86.15  ? 117  GLN   N OE1 1 
ATOM   889  N  NE2 . GLN   A 1 117 ? 125.476 140.156 200.098 1.00 86.15  ? 117  GLN   N NE2 1 
ATOM   890  N  N   . VAL   A 1 118 ? 129.414 138.524 198.133 1.00 88.29  ? 118  VAL   N N   1 
ATOM   891  C  CA  . VAL   A 1 118 ? 130.457 137.693 198.717 1.00 88.29  ? 118  VAL   N CA  1 
ATOM   892  C  C   . VAL   A 1 118 ? 130.238 137.672 200.221 1.00 88.29  ? 118  VAL   N C   1 
ATOM   893  O  O   . VAL   A 1 118 ? 130.346 138.712 200.884 1.00 88.29  ? 118  VAL   N O   1 
ATOM   894  C  CB  . VAL   A 1 118 ? 131.862 138.209 198.375 1.00 88.29  ? 118  VAL   N CB  1 
ATOM   895  C  CG1 . VAL   A 1 118 ? 132.913 137.461 199.181 1.00 88.29  ? 118  VAL   N CG1 1 
ATOM   896  C  CG2 . VAL   A 1 118 ? 132.125 138.070 196.886 1.00 88.29  ? 118  VAL   N CG2 1 
ATOM   897  N  N   . THR   A 1 119 ? 129.926 136.494 200.755 1.00 96.65  ? 119  THR   N N   1 
ATOM   898  C  CA  . THR   A 1 119 ? 129.727 136.303 202.188 1.00 96.65  ? 119  THR   N CA  1 
ATOM   899  C  C   . THR   A 1 119 ? 130.813 135.368 202.695 1.00 96.65  ? 119  THR   N C   1 
ATOM   900  O  O   . THR   A 1 119 ? 130.816 134.179 202.365 1.00 96.65  ? 119  THR   N O   1 
ATOM   901  C  CB  . THR   A 1 119 ? 128.344 135.728 202.487 1.00 96.65  ? 119  THR   N CB  1 
ATOM   902  O  OG1 . THR   A 1 119 ? 128.214 134.445 201.863 1.00 96.65  ? 119  THR   N OG1 1 
ATOM   903  C  CG2 . THR   A 1 119 ? 127.258 136.646 201.967 1.00 96.65  ? 119  THR   N CG2 1 
ATOM   904  N  N   . VAL   A 1 120 ? 131.738 135.895 203.486 1.00 100.99 ? 120  VAL   N N   1 
ATOM   905  C  CA  . VAL   A 1 120 ? 132.740 135.072 204.147 1.00 100.99 ? 120  VAL   N CA  1 
ATOM   906  C  C   . VAL   A 1 120 ? 132.270 134.795 205.570 1.00 100.99 ? 120  VAL   N C   1 
ATOM   907  O  O   . VAL   A 1 120 ? 131.818 135.702 206.283 1.00 100.99 ? 120  VAL   N O   1 
ATOM   908  C  CB  . VAL   A 1 120 ? 134.138 135.721 204.089 1.00 100.99 ? 120  VAL   N CB  1 
ATOM   909  C  CG1 . VAL   A 1 120 ? 134.171 137.086 204.734 1.00 100.99 ? 120  VAL   N CG1 1 
ATOM   910  C  CG2 . VAL   A 1 120 ? 135.166 134.817 204.737 1.00 100.99 ? 120  VAL   N CG2 1 
ATOM   911  N  N   . SER   A 1 121 ? 132.304 133.523 205.955 1.00 111.67 ? 121  SER   N N   1 
ATOM   912  C  CA  . SER   A 1 121 ? 131.734 133.074 207.217 1.00 111.67 ? 121  SER   N CA  1 
ATOM   913  C  C   . SER   A 1 121 ? 132.788 132.330 208.018 1.00 111.67 ? 121  SER   N C   1 
ATOM   914  O  O   . SER   A 1 121 ? 133.481 131.460 207.482 1.00 111.67 ? 121  SER   N O   1 
ATOM   915  C  CB  . SER   A 1 121 ? 130.515 132.176 206.984 1.00 111.67 ? 121  SER   N CB  1 
ATOM   916  O  OG  . SER   A 1 121 ? 130.900 130.924 206.446 1.00 111.67 ? 121  SER   N OG  1 
ATOM   917  N  N   . SER   A 1 122 ? 132.902 132.674 209.298 1.00 121.14 ? 122  SER   N N   1 
ATOM   918  C  CA  . SER   A 1 122 ? 133.807 132.003 210.218 1.00 121.14 ? 122  SER   N CA  1 
ATOM   919  C  C   . SER   A 1 122 ? 133.130 130.867 210.971 1.00 121.14 ? 122  SER   N C   1 
ATOM   920  O  O   . SER   A 1 122 ? 133.749 130.268 211.857 1.00 121.14 ? 122  SER   N O   1 
ATOM   921  C  CB  . SER   A 1 122 ? 134.395 133.012 211.206 1.00 121.14 ? 122  SER   N CB  1 
ATOM   922  O  OG  . SER   A 1 122 ? 134.979 134.108 210.526 1.00 121.14 ? 122  SER   N OG  1 
ATOM   923  N  N   . HIS   A 1 123 ? 131.874 130.566 210.644 1.00 130.07 ? 123  HIS   N N   1 
ATOM   924  C  CA  . HIS   A 1 123 ? 131.136 129.523 211.342 1.00 130.07 ? 123  HIS   N CA  1 
ATOM   925  C  C   . HIS   A 1 123 ? 131.686 128.149 210.977 1.00 130.07 ? 123  HIS   N C   1 
ATOM   926  O  O   . HIS   A 1 123 ? 131.833 127.820 209.796 1.00 130.07 ? 123  HIS   N O   1 
ATOM   927  C  CB  . HIS   A 1 123 ? 129.650 129.612 210.992 1.00 130.07 ? 123  HIS   N CB  1 
ATOM   928  C  CG  . HIS   A 1 123 ? 128.764 128.786 211.872 1.00 130.07 ? 123  HIS   N CG  1 
ATOM   929  N  ND1 . HIS   A 1 123 ? 127.415 128.632 211.632 1.00 130.07 ? 123  HIS   N ND1 1 
ATOM   930  C  CD2 . HIS   A 1 123 ? 129.028 128.080 212.997 1.00 130.07 ? 123  HIS   N CD2 1 
ATOM   931  C  CE1 . HIS   A 1 123 ? 126.889 127.859 212.565 1.00 130.07 ? 123  HIS   N CE1 1 
ATOM   932  N  NE2 . HIS   A 1 123 ? 127.846 127.511 213.406 1.00 130.07 ? 123  HIS   N NE2 1 
ATOM   933  N  N   . HIS   A 1 124 ? 131.990 127.350 211.994 1.00 132.94 ? 124  HIS   N N   1 
ATOM   934  C  CA  . HIS   A 1 124 ? 132.479 125.993 211.790 1.00 132.94 ? 124  HIS   N CA  1 
ATOM   935  C  C   . HIS   A 1 124 ? 131.321 125.003 211.764 1.00 132.94 ? 124  HIS   N C   1 
ATOM   936  O  O   . HIS   A 1 124 ? 130.487 124.989 212.670 1.00 132.94 ? 124  HIS   N O   1 
ATOM   937  C  CB  . HIS   A 1 124 ? 133.475 125.606 212.885 1.00 132.94 ? 124  HIS   N CB  1 
ATOM   938  C  CG  . HIS   A 1 124 ? 134.752 126.385 212.847 1.00 132.94 ? 124  HIS   N CG  1 
ATOM   939  N  ND1 . HIS   A 1 124 ? 135.752 126.130 211.933 1.00 132.94 ? 124  HIS   N ND1 1 
ATOM   940  C  CD2 . HIS   A 1 124 ? 135.193 127.412 213.611 1.00 132.94 ? 124  HIS   N CD2 1 
ATOM   941  C  CE1 . HIS   A 1 124 ? 136.754 126.967 212.136 1.00 132.94 ? 124  HIS   N CE1 1 
ATOM   942  N  NE2 . HIS   A 1 124 ? 136.440 127.756 213.148 1.00 132.94 ? 124  HIS   N NE2 1 
ATOM   943  N  N   . GLU   B 2 38  ? 150.220 140.040 121.915 1.00 89.85  ? 100  GLU   R N   1 
ATOM   944  C  CA  . GLU   B 2 38  ? 149.947 138.697 122.413 1.00 89.85  ? 100  GLU   R CA  1 
ATOM   945  C  C   . GLU   B 2 38  ? 151.026 138.255 123.391 1.00 89.85  ? 100  GLU   R C   1 
ATOM   946  O  O   . GLU   B 2 38  ? 150.950 137.171 123.968 1.00 89.85  ? 100  GLU   R O   1 
ATOM   947  C  CB  . GLU   B 2 38  ? 149.854 137.702 121.256 1.00 89.85  ? 100  GLU   R CB  1 
ATOM   948  C  CG  . GLU   B 2 38  ? 151.195 137.360 120.629 1.00 89.85  ? 100  GLU   R CG  1 
ATOM   949  C  CD  . GLU   B 2 38  ? 151.516 138.221 119.427 1.00 89.85  ? 100  GLU   R CD  1 
ATOM   950  O  OE1 . GLU   B 2 38  ? 150.774 139.191 119.175 1.00 89.85  ? 100  GLU   R OE1 1 
ATOM   951  O  OE2 . GLU   B 2 38  ? 152.514 137.931 118.736 1.00 89.85  ? 100  GLU   R OE2 1 
ATOM   952  N  N   . ASN   B 2 39  ? 152.035 139.102 123.569 1.00 89.32  ? 101  ASN   R N   1 
ATOM   953  C  CA  . ASN   B 2 39  ? 153.164 138.808 124.436 1.00 89.32  ? 101  ASN   R CA  1 
ATOM   954  C  C   . ASN   B 2 39  ? 153.349 139.919 125.458 1.00 89.32  ? 101  ASN   R C   1 
ATOM   955  O  O   . ASN   B 2 39  ? 153.087 141.094 125.184 1.00 89.32  ? 101  ASN   R O   1 
ATOM   956  C  CB  . ASN   B 2 39  ? 154.461 138.645 123.635 1.00 89.32  ? 101  ASN   R CB  1 
ATOM   957  C  CG  . ASN   B 2 39  ? 154.448 137.428 122.741 1.00 89.32  ? 101  ASN   R CG  1 
ATOM   958  O  OD1 . ASN   B 2 39  ? 153.570 136.575 122.845 1.00 89.32  ? 101  ASN   R OD1 1 
ATOM   959  N  ND2 . ASN   B 2 39  ? 155.430 137.339 121.853 1.00 89.32  ? 101  ASN   R ND2 1 
ATOM   960  N  N   . PHE   B 2 40  ? 153.802 139.528 126.644 1.00 88.92  ? 102  PHE   R N   1 
ATOM   961  C  CA  . PHE   B 2 40  ? 154.253 140.482 127.641 1.00 88.92  ? 102  PHE   R CA  1 
ATOM   962  C  C   . PHE   B 2 40  ? 155.577 141.087 127.180 1.00 88.92  ? 102  PHE   R C   1 
ATOM   963  O  O   . PHE   B 2 40  ? 156.302 140.490 126.378 1.00 88.92  ? 102  PHE   R O   1 
ATOM   964  C  CB  . PHE   B 2 40  ? 154.386 139.775 128.991 1.00 88.92  ? 102  PHE   R CB  1 
ATOM   965  C  CG  . PHE   B 2 40  ? 154.333 140.687 130.178 1.00 88.92  ? 102  PHE   R CG  1 
ATOM   966  C  CD1 . PHE   B 2 40  ? 153.168 141.367 130.488 1.00 88.92  ? 102  PHE   R CD1 1 
ATOM   967  C  CD2 . PHE   B 2 40  ? 155.413 140.796 131.035 1.00 88.92  ? 102  PHE   R CD2 1 
ATOM   968  C  CE1 . PHE   B 2 40  ? 153.100 142.192 131.595 1.00 88.92  ? 102  PHE   R CE1 1 
ATOM   969  C  CE2 . PHE   B 2 40  ? 155.348 141.610 132.153 1.00 88.92  ? 102  PHE   R CE2 1 
ATOM   970  C  CZ  . PHE   B 2 40  ? 154.192 142.312 132.429 1.00 88.92  ? 102  PHE   R CZ  1 
ATOM   971  N  N   . MET   B 2 41  ? 155.876 142.294 127.678 1.00 93.52  ? 103  MET   R N   1 
ATOM   972  C  CA  . MET   B 2 41  ? 157.051 143.080 127.277 1.00 93.52  ? 103  MET   R CA  1 
ATOM   973  C  C   . MET   B 2 41  ? 157.054 143.337 125.765 1.00 93.52  ? 103  MET   R C   1 
ATOM   974  O  O   . MET   B 2 41  ? 157.879 142.814 125.016 1.00 93.52  ? 103  MET   R O   1 
ATOM   975  C  CB  . MET   B 2 41  ? 158.370 142.414 127.698 1.00 93.52  ? 103  MET   R CB  1 
ATOM   976  C  CG  . MET   B 2 41  ? 158.878 142.623 129.121 1.00 93.52  ? 103  MET   R CG  1 
ATOM   977  S  SD  . MET   B 2 41  ? 158.828 144.260 129.871 1.00 93.52  ? 103  MET   R SD  1 
ATOM   978  C  CE  . MET   B 2 41  ? 157.275 144.188 130.744 1.00 93.52  ? 103  MET   R CE  1 
ATOM   979  N  N   . ASP   B 2 42  ? 156.083 144.130 125.326 1.00 104.13 ? 104  ASP   R N   1 
ATOM   980  C  CA  . ASP   B 2 42  ? 156.008 144.517 123.918 1.00 104.13 ? 104  ASP   R CA  1 
ATOM   981  C  C   . ASP   B 2 42  ? 156.849 145.773 123.720 1.00 104.13 ? 104  ASP   R C   1 
ATOM   982  O  O   . ASP   B 2 42  ? 156.382 146.893 123.943 1.00 104.13 ? 104  ASP   R O   1 
ATOM   983  C  CB  . ASP   B 2 42  ? 154.564 144.731 123.482 1.00 104.13 ? 104  ASP   R CB  1 
ATOM   984  C  CG  . ASP   B 2 42  ? 154.392 144.612 121.979 1.00 104.13 ? 104  ASP   R CG  1 
ATOM   985  O  OD1 . ASP   B 2 42  ? 155.353 144.184 121.305 1.00 104.13 ? 104  ASP   R OD1 1 
ATOM   986  O  OD2 . ASP   B 2 42  ? 153.301 144.942 121.470 1.00 104.13 ? 104  ASP   R OD2 1 
ATOM   987  N  N   . ILE   B 2 43  ? 158.100 145.578 123.298 1.00 103.06 ? 105  ILE   R N   1 
ATOM   988  C  CA  . ILE   B 2 43  ? 159.013 146.678 122.994 1.00 103.06 ? 105  ILE   R CA  1 
ATOM   989  C  C   . ILE   B 2 43  ? 159.135 146.901 121.487 1.00 103.06 ? 105  ILE   R C   1 
ATOM   990  O  O   . ILE   B 2 43  ? 159.553 147.990 121.059 1.00 103.06 ? 105  ILE   R O   1 
ATOM   991  C  CB  . ILE   B 2 43  ? 160.388 146.424 123.664 1.00 103.06 ? 105  ILE   R CB  1 
ATOM   992  C  CG1 . ILE   B 2 43  ? 160.209 146.276 125.170 1.00 103.06 ? 105  ILE   R CG1 1 
ATOM   993  C  CG2 . ILE   B 2 43  ? 161.368 147.579 123.505 1.00 103.06 ? 105  ILE   R CG2 1 
ATOM   994  C  CD1 . ILE   B 2 43  ? 160.314 144.876 125.688 1.00 103.06 ? 105  ILE   R CD1 1 
ATOM   995  N  N   . GLU   B 2 44  ? 158.709 145.934 120.667 1.00 109.38 ? 106  GLU   R N   1 
ATOM   996  C  CA  . GLU   B 2 44  ? 158.770 146.085 119.216 1.00 109.38 ? 106  GLU   R CA  1 
ATOM   997  C  C   . GLU   B 2 44  ? 157.857 147.193 118.698 1.00 109.38 ? 106  GLU   R C   1 
ATOM   998  O  O   . GLU   B 2 44  ? 158.064 147.674 117.579 1.00 109.38 ? 106  GLU   R O   1 
ATOM   999  C  CB  . GLU   B 2 44  ? 158.421 144.760 118.539 1.00 109.38 ? 106  GLU   R CB  1 
ATOM   1000 C  CG  . GLU   B 2 44  ? 159.636 143.959 118.097 1.00 109.38 ? 106  GLU   R CG  1 
ATOM   1001 C  CD  . GLU   B 2 44  ? 159.350 142.475 117.986 1.00 109.38 ? 106  GLU   R CD  1 
ATOM   1002 O  OE1 . GLU   B 2 44  ? 160.314 141.681 118.002 1.00 109.38 ? 106  GLU   R OE1 1 
ATOM   1003 O  OE2 . GLU   B 2 44  ? 158.164 142.102 117.877 1.00 109.38 ? 106  GLU   R OE2 1 
ATOM   1004 N  N   . CYS   B 2 45  ? 156.861 147.608 119.478 1.00 114.83 ? 107  CYS   R N   1 
ATOM   1005 C  CA  . CYS   B 2 45  ? 156.075 148.784 119.141 1.00 114.83 ? 107  CYS   R CA  1 
ATOM   1006 C  C   . CYS   B 2 45  ? 156.925 150.046 119.295 1.00 114.83 ? 107  CYS   R C   1 
ATOM   1007 O  O   . CYS   B 2 45  ? 158.000 150.031 119.901 1.00 114.83 ? 107  CYS   R O   1 
ATOM   1008 C  CB  . CYS   B 2 45  ? 154.833 148.868 120.026 1.00 114.83 ? 107  CYS   R CB  1 
ATOM   1009 S  SG  . CYS   B 2 45  ? 155.190 149.216 121.764 1.00 114.83 ? 107  CYS   R SG  1 
ATOM   1010 N  N   . PHE   B 2 46  ? 156.419 151.152 118.735 1.00 124.98 ? 108  PHE   R N   1 
ATOM   1011 C  CA  . PHE   B 2 46  ? 157.105 152.449 118.705 1.00 124.98 ? 108  PHE   R CA  1 
ATOM   1012 C  C   . PHE   B 2 46  ? 158.470 152.326 118.016 1.00 124.98 ? 108  PHE   R C   1 
ATOM   1013 O  O   . PHE   B 2 46  ? 159.533 152.441 118.628 1.00 124.98 ? 108  PHE   R O   1 
ATOM   1014 C  CB  . PHE   B 2 46  ? 157.238 153.058 120.109 1.00 124.98 ? 108  PHE   R CB  1 
ATOM   1015 C  CG  . PHE   B 2 46  ? 157.652 154.504 120.106 1.00 124.98 ? 108  PHE   R CG  1 
ATOM   1016 C  CD1 . PHE   B 2 46  ? 156.805 155.482 119.605 1.00 124.98 ? 108  PHE   R CD1 1 
ATOM   1017 C  CD2 . PHE   B 2 46  ? 158.891 154.885 120.602 1.00 124.98 ? 108  PHE   R CD2 1 
ATOM   1018 C  CE1 . PHE   B 2 46  ? 157.183 156.813 119.601 1.00 124.98 ? 108  PHE   R CE1 1 
ATOM   1019 C  CE2 . PHE   B 2 46  ? 159.276 156.215 120.600 1.00 124.98 ? 108  PHE   R CE2 1 
ATOM   1020 C  CZ  . PHE   B 2 46  ? 158.420 157.180 120.099 1.00 124.98 ? 108  PHE   R CZ  1 
ATOM   1021 N  N   . MET   B 2 47  ? 158.401 152.074 116.707 1.00 126.92 ? 109  MET   R N   1 
ATOM   1022 C  CA  . MET   B 2 47  ? 159.546 151.842 115.822 1.00 126.92 ? 109  MET   R CA  1 
ATOM   1023 C  C   . MET   B 2 47  ? 160.448 153.080 115.625 1.00 126.92 ? 109  MET   R C   1 
ATOM   1024 O  O   . MET   B 2 47  ? 161.358 152.999 114.788 1.00 126.92 ? 109  MET   R O   1 
ATOM   1025 C  CB  . MET   B 2 47  ? 159.052 151.344 114.463 1.00 126.92 ? 109  MET   R CB  1 
ATOM   1026 N  N   . VAL   B 2 48  ? 160.218 154.186 116.340 1.00 128.36 ? 110  VAL   R N   1 
ATOM   1027 C  CA  . VAL   B 2 48  ? 161.112 155.340 116.293 1.00 128.36 ? 110  VAL   R CA  1 
ATOM   1028 C  C   . VAL   B 2 48  ? 162.491 154.974 116.837 1.00 128.36 ? 110  VAL   R C   1 
ATOM   1029 O  O   . VAL   B 2 48  ? 163.510 155.536 116.410 1.00 128.36 ? 110  VAL   R O   1 
ATOM   1030 C  CB  . VAL   B 2 48  ? 160.466 156.511 117.069 1.00 128.36 ? 110  VAL   R CB  1 
ATOM   1031 C  CG1 . VAL   B 2 48  ? 161.364 157.744 117.107 1.00 128.36 ? 110  VAL   R CG1 1 
ATOM   1032 C  CG2 . VAL   B 2 48  ? 159.111 156.855 116.468 1.00 128.36 ? 110  VAL   R CG2 1 
ATOM   1033 N  N   . LEU   B 2 49  ? 162.551 153.997 117.739 1.00 124.03 ? 111  LEU   R N   1 
ATOM   1034 C  CA  . LEU   B 2 49  ? 163.795 153.588 118.390 1.00 124.03 ? 111  LEU   R CA  1 
ATOM   1035 C  C   . LEU   B 2 49  ? 164.703 152.919 117.366 1.00 124.03 ? 111  LEU   R C   1 
ATOM   1036 O  O   . LEU   B 2 49  ? 164.520 151.752 117.017 1.00 124.03 ? 111  LEU   R O   1 
ATOM   1037 C  CB  . LEU   B 2 49  ? 163.495 152.647 119.550 1.00 124.03 ? 111  LEU   R CB  1 
ATOM   1038 C  CG  . LEU   B 2 49  ? 162.343 153.045 120.474 1.00 124.03 ? 111  LEU   R CG  1 
ATOM   1039 C  CD1 . LEU   B 2 49  ? 162.102 151.972 121.524 1.00 124.03 ? 111  LEU   R CD1 1 
ATOM   1040 C  CD2 . LEU   B 2 49  ? 162.608 154.396 121.129 1.00 124.03 ? 111  LEU   R CD2 1 
ATOM   1041 N  N   . ASN   B 2 50  ? 165.680 153.675 116.872 1.00 120.61 ? 112  ASN   R N   1 
ATOM   1042 C  CA  . ASN   B 2 50  ? 166.683 153.136 115.975 1.00 120.61 ? 112  ASN   R CA  1 
ATOM   1043 C  C   . ASN   B 2 50  ? 167.622 152.215 116.752 1.00 120.61 ? 112  ASN   R C   1 
ATOM   1044 O  O   . ASN   B 2 50  ? 167.707 152.302 117.979 1.00 120.61 ? 112  ASN   R O   1 
ATOM   1045 C  CB  . ASN   B 2 50  ? 167.463 154.277 115.324 1.00 120.61 ? 112  ASN   R CB  1 
ATOM   1046 C  CG  . ASN   B 2 50  ? 166.590 155.152 114.451 1.00 120.61 ? 112  ASN   R CG  1 
ATOM   1047 O  OD1 . ASN   B 2 50  ? 166.381 156.329 114.743 1.00 120.61 ? 112  ASN   R OD1 1 
ATOM   1048 N  ND2 . ASN   B 2 50  ? 166.071 154.580 113.371 1.00 120.61 ? 112  ASN   R ND2 1 
ATOM   1049 N  N   . PRO   B 2 51  ? 168.328 151.310 116.062 1.00 115.01 ? 113  PRO   R N   1 
ATOM   1050 C  CA  . PRO   B 2 51  ? 169.301 150.452 116.765 1.00 115.01 ? 113  PRO   R CA  1 
ATOM   1051 C  C   . PRO   B 2 51  ? 170.429 151.218 117.438 1.00 115.01 ? 113  PRO   R C   1 
ATOM   1052 O  O   . PRO   B 2 51  ? 171.091 150.663 118.324 1.00 115.01 ? 113  PRO   R O   1 
ATOM   1053 C  CB  . PRO   B 2 51  ? 169.831 149.541 115.652 1.00 115.01 ? 113  PRO   R CB  1 
ATOM   1054 C  CG  . PRO   B 2 51  ? 168.721 149.478 114.671 1.00 115.01 ? 113  PRO   R CG  1 
ATOM   1055 C  CD  . PRO   B 2 51  ? 168.087 150.838 114.685 1.00 115.01 ? 113  PRO   R CD  1 
ATOM   1056 N  N   . SER   B 2 52  ? 170.674 152.469 117.043 1.00 117.22 ? 114  SER   R N   1 
ATOM   1057 C  CA  . SER   B 2 52  ? 171.619 153.313 117.760 1.00 117.22 ? 114  SER   R CA  1 
ATOM   1058 C  C   . SER   B 2 52  ? 171.138 153.666 119.164 1.00 117.22 ? 114  SER   R C   1 
ATOM   1059 O  O   . SER   B 2 52  ? 171.967 153.976 120.026 1.00 117.22 ? 114  SER   R O   1 
ATOM   1060 C  CB  . SER   B 2 52  ? 171.888 154.587 116.959 1.00 117.22 ? 114  SER   R CB  1 
ATOM   1061 O  OG  . SER   B 2 52  ? 170.707 155.350 116.802 1.00 117.22 ? 114  SER   R OG  1 
ATOM   1062 N  N   . GLN   B 2 53  ? 169.825 153.629 119.416 1.00 115.31 ? 115  GLN   R N   1 
ATOM   1063 C  CA  . GLN   B 2 53  ? 169.290 153.906 120.741 1.00 115.31 ? 115  GLN   R CA  1 
ATOM   1064 C  C   . GLN   B 2 53  ? 168.521 152.747 121.359 1.00 115.31 ? 115  GLN   R C   1 
ATOM   1065 O  O   . GLN   B 2 53  ? 168.174 152.829 122.541 1.00 115.31 ? 115  GLN   R O   1 
ATOM   1066 C  CB  . GLN   B 2 53  ? 168.375 155.141 120.712 1.00 115.31 ? 115  GLN   R CB  1 
ATOM   1067 C  CG  . GLN   B 2 53  ? 167.286 155.090 119.661 1.00 115.31 ? 115  GLN   R CG  1 
ATOM   1068 C  CD  . GLN   B 2 53  ? 167.642 155.891 118.428 1.00 115.31 ? 115  GLN   R CD  1 
ATOM   1069 O  OE1 . GLN   B 2 53  ? 168.772 155.835 117.946 1.00 115.31 ? 115  GLN   R OE1 1 
ATOM   1070 N  NE2 . GLN   B 2 53  ? 166.678 156.640 117.906 1.00 115.31 ? 115  GLN   R NE2 1 
ATOM   1071 N  N   . GLN   B 2 54  ? 168.241 151.680 120.605 1.00 108.82 ? 116  GLN   R N   1 
ATOM   1072 C  CA  . GLN   B 2 54  ? 167.568 150.521 121.186 1.00 108.82 ? 116  GLN   R CA  1 
ATOM   1073 C  C   . GLN   B 2 54  ? 168.435 149.853 122.245 1.00 108.82 ? 116  GLN   R C   1 
ATOM   1074 O  O   . GLN   B 2 54  ? 167.937 149.449 123.304 1.00 108.82 ? 116  GLN   R O   1 
ATOM   1075 C  CB  . GLN   B 2 54  ? 167.201 149.521 120.091 1.00 108.82 ? 116  GLN   R CB  1 
ATOM   1076 C  CG  . GLN   B 2 54  ? 165.952 149.884 119.319 1.00 108.82 ? 116  GLN   R CG  1 
ATOM   1077 C  CD  . GLN   B 2 54  ? 165.278 148.679 118.701 1.00 108.82 ? 116  GLN   R CD  1 
ATOM   1078 O  OE1 . GLN   B 2 54  ? 165.133 147.638 119.342 1.00 108.82 ? 116  GLN   R OE1 1 
ATOM   1079 N  NE2 . GLN   B 2 54  ? 164.865 148.811 117.446 1.00 108.82 ? 116  GLN   R NE2 1 
ATOM   1080 N  N   . LEU   B 2 55  ? 169.738 149.741 121.981 1.00 101.21 ? 117  LEU   R N   1 
ATOM   1081 C  CA  . LEU   B 2 55  ? 170.648 149.186 122.976 1.00 101.21 ? 117  LEU   R CA  1 
ATOM   1082 C  C   . LEU   B 2 55  ? 170.757 150.105 124.186 1.00 101.21 ? 117  LEU   R C   1 
ATOM   1083 O  O   . LEU   B 2 55  ? 170.919 149.635 125.317 1.00 101.21 ? 117  LEU   R O   1 
ATOM   1084 C  CB  . LEU   B 2 55  ? 172.029 148.936 122.364 1.00 101.21 ? 117  LEU   R CB  1 
ATOM   1085 C  CG  . LEU   B 2 55  ? 172.271 147.703 121.479 1.00 101.21 ? 117  LEU   R CG  1 
ATOM   1086 C  CD1 . LEU   B 2 55  ? 171.614 147.804 120.105 1.00 101.21 ? 117  LEU   R CD1 1 
ATOM   1087 C  CD2 . LEU   B 2 55  ? 173.761 147.436 121.337 1.00 101.21 ? 117  LEU   R CD2 1 
ATOM   1088 N  N   . ALA   B 2 56  ? 170.659 151.420 123.966 1.00 97.19  ? 118  ALA   R N   1 
ATOM   1089 C  CA  . ALA   B 2 56  ? 170.654 152.363 125.081 1.00 97.19  ? 118  ALA   R CA  1 
ATOM   1090 C  C   . ALA   B 2 56  ? 169.419 152.185 125.955 1.00 97.19  ? 118  ALA   R C   1 
ATOM   1091 O  O   . ALA   B 2 56  ? 169.520 152.200 127.187 1.00 97.19  ? 118  ALA   R O   1 
ATOM   1092 C  CB  . ALA   B 2 56  ? 170.739 153.795 124.557 1.00 97.19  ? 118  ALA   R CB  1 
ATOM   1093 N  N   . ILE   B 2 57  ? 168.249 152.008 125.332 1.00 90.85  ? 119  ILE   R N   1 
ATOM   1094 C  CA  . ILE   B 2 57  ? 167.025 151.744 126.089 1.00 90.85  ? 119  ILE   R CA  1 
ATOM   1095 C  C   . ILE   B 2 57  ? 167.148 150.442 126.866 1.00 90.85  ? 119  ILE   R C   1 
ATOM   1096 O  O   . ILE   B 2 57  ? 166.777 150.368 128.047 1.00 90.85  ? 119  ILE   R O   1 
ATOM   1097 C  CB  . ILE   B 2 57  ? 165.798 151.732 125.156 1.00 90.85  ? 119  ILE   R CB  1 
ATOM   1098 C  CG1 . ILE   B 2 57  ? 165.630 153.082 124.460 1.00 90.85  ? 119  ILE   R CG1 1 
ATOM   1099 C  CG2 . ILE   B 2 57  ? 164.542 151.369 125.920 1.00 90.85  ? 119  ILE   R CG2 1 
ATOM   1100 C  CD1 . ILE   B 2 57  ? 165.408 154.234 125.408 1.00 90.85  ? 119  ILE   R CD1 1 
ATOM   1101 N  N   . ALA   B 2 58  ? 167.694 149.406 126.224 1.00 90.81  ? 120  ALA   R N   1 
ATOM   1102 C  CA  . ALA   B 2 58  ? 167.855 148.116 126.888 1.00 90.81  ? 120  ALA   R CA  1 
ATOM   1103 C  C   . ALA   B 2 58  ? 168.791 148.214 128.087 1.00 90.81  ? 120  ALA   R C   1 
ATOM   1104 O  O   . ALA   B 2 58  ? 168.487 147.685 129.164 1.00 90.81  ? 120  ALA   R O   1 
ATOM   1105 C  CB  . ALA   B 2 58  ? 168.369 147.077 125.893 1.00 90.81  ? 120  ALA   R CB  1 
ATOM   1106 N  N   . VAL   B 2 59  ? 169.916 148.916 127.934 1.00 87.50  ? 121  VAL   R N   1 
ATOM   1107 C  CA  . VAL   B 2 59  ? 170.870 148.981 129.034 1.00 87.50  ? 121  VAL   R CA  1 
ATOM   1108 C  C   . VAL   B 2 59  ? 170.358 149.887 130.153 1.00 87.50  ? 121  VAL   R C   1 
ATOM   1109 O  O   . VAL   B 2 59  ? 170.612 149.613 131.332 1.00 87.50  ? 121  VAL   R O   1 
ATOM   1110 C  CB  . VAL   B 2 59  ? 172.272 149.387 128.526 1.00 87.50  ? 121  VAL   R CB  1 
ATOM   1111 C  CG1 . VAL   B 2 59  ? 172.329 150.837 128.073 1.00 87.50  ? 121  VAL   R CG1 1 
ATOM   1112 C  CG2 . VAL   B 2 59  ? 173.332 149.103 129.584 1.00 87.50  ? 121  VAL   R CG2 1 
ATOM   1113 N  N   . LEU   B 2 60  ? 169.591 150.941 129.834 1.00 85.94  ? 122  LEU   R N   1 
ATOM   1114 C  CA  . LEU   B 2 60  ? 169.066 151.775 130.913 1.00 85.94  ? 122  LEU   R CA  1 
ATOM   1115 C  C   . LEU   B 2 60  ? 167.971 151.045 131.678 1.00 85.94  ? 122  LEU   R C   1 
ATOM   1116 O  O   . LEU   B 2 60  ? 167.884 151.164 132.905 1.00 85.94  ? 122  LEU   R O   1 
ATOM   1117 C  CB  . LEU   B 2 60  ? 168.562 153.125 130.386 1.00 85.94  ? 122  LEU   R CB  1 
ATOM   1118 C  CG  . LEU   B 2 60  ? 167.426 153.347 129.380 1.00 85.94  ? 122  LEU   R CG  1 
ATOM   1119 C  CD1 . LEU   B 2 60  ? 166.035 153.344 130.015 1.00 85.94  ? 122  LEU   R CD1 1 
ATOM   1120 C  CD2 . LEU   B 2 60  ? 167.654 154.639 128.610 1.00 85.94  ? 122  LEU   R CD2 1 
ATOM   1121 N  N   . SER   B 2 61  ? 167.142 150.267 130.975 1.00 80.64  ? 123  SER   R N   1 
ATOM   1122 C  CA  . SER   B 2 61  ? 166.141 149.455 131.656 1.00 80.64  ? 123  SER   R CA  1 
ATOM   1123 C  C   . SER   B 2 61  ? 166.793 148.393 132.533 1.00 80.64  ? 123  SER   R C   1 
ATOM   1124 O  O   . SER   B 2 61  ? 166.352 148.159 133.666 1.00 80.64  ? 123  SER   R O   1 
ATOM   1125 C  CB  . SER   B 2 61  ? 165.210 148.811 130.632 1.00 80.64  ? 123  SER   R CB  1 
ATOM   1126 O  OG  . SER   B 2 61  ? 164.513 149.800 129.897 1.00 80.64  ? 123  SER   R OG  1 
ATOM   1127 N  N   . LEU   B 2 62  ? 167.855 147.753 132.033 1.00 81.10  ? 124  LEU   R N   1 
ATOM   1128 C  CA  . LEU   B 2 62  ? 168.555 146.744 132.822 1.00 81.10  ? 124  LEU   R CA  1 
ATOM   1129 C  C   . LEU   B 2 62  ? 169.207 147.348 134.060 1.00 81.10  ? 124  LEU   R C   1 
ATOM   1130 O  O   . LEU   B 2 62  ? 169.123 146.775 135.153 1.00 81.10  ? 124  LEU   R O   1 
ATOM   1131 C  CB  . LEU   B 2 62  ? 169.598 146.037 131.959 1.00 81.10  ? 124  LEU   R CB  1 
ATOM   1132 C  CG  . LEU   B 2 62  ? 169.071 144.883 131.107 1.00 81.10  ? 124  LEU   R CG  1 
ATOM   1133 C  CD1 . LEU   B 2 62  ? 169.958 144.665 129.894 1.00 81.10  ? 124  LEU   R CD1 1 
ATOM   1134 C  CD2 . LEU   B 2 62  ? 168.969 143.617 131.942 1.00 81.10  ? 124  LEU   R CD2 1 
ATOM   1135 N  N   . THR   B 2 63  ? 169.852 148.510 133.913 1.00 80.87  ? 125  THR   R N   1 
ATOM   1136 C  CA  . THR   B 2 63  ? 170.489 149.141 135.063 1.00 80.87  ? 125  THR   R CA  1 
ATOM   1137 C  C   . THR   B 2 63  ? 169.466 149.656 136.065 1.00 80.87  ? 125  THR   R C   1 
ATOM   1138 O  O   . THR   B 2 63  ? 169.701 149.570 137.274 1.00 80.87  ? 125  THR   R O   1 
ATOM   1139 C  CB  . THR   B 2 63  ? 171.404 150.280 134.616 1.00 80.87  ? 125  THR   R CB  1 
ATOM   1140 O  OG1 . THR   B 2 63  ? 170.688 151.163 133.744 1.00 80.87  ? 125  THR   R OG1 1 
ATOM   1141 C  CG2 . THR   B 2 63  ? 172.634 149.734 133.907 1.00 80.87  ? 125  THR   R CG2 1 
ATOM   1142 N  N   . LEU   B 2 64  ? 168.320 150.156 135.595 1.00 75.17  ? 126  LEU   R N   1 
ATOM   1143 C  CA  . LEU   B 2 64  ? 167.277 150.593 136.516 1.00 75.17  ? 126  LEU   R CA  1 
ATOM   1144 C  C   . LEU   B 2 64  ? 166.685 149.416 137.281 1.00 75.17  ? 126  LEU   R C   1 
ATOM   1145 O  O   . LEU   B 2 64  ? 166.475 149.507 138.497 1.00 75.17  ? 126  LEU   R O   1 
ATOM   1146 C  CB  . LEU   B 2 64  ? 166.188 151.344 135.755 1.00 75.17  ? 126  LEU   R CB  1 
ATOM   1147 C  CG  . LEU   B 2 64  ? 165.512 152.472 136.532 1.00 75.17  ? 126  LEU   R CG  1 
ATOM   1148 C  CD1 . LEU   B 2 64  ? 166.548 153.488 136.979 1.00 75.17  ? 126  LEU   R CD1 1 
ATOM   1149 C  CD2 . LEU   B 2 64  ? 164.432 153.137 135.693 1.00 75.17  ? 126  LEU   R CD2 1 
ATOM   1150 N  N   . GLY   B 2 65  ? 166.426 148.300 136.593 1.00 73.88  ? 127  GLY   R N   1 
ATOM   1151 C  CA  . GLY   B 2 65  ? 165.915 147.124 137.278 1.00 73.88  ? 127  GLY   R CA  1 
ATOM   1152 C  C   . GLY   B 2 65  ? 166.898 146.555 138.283 1.00 73.88  ? 127  GLY   R C   1 
ATOM   1153 O  O   . GLY   B 2 65  ? 166.520 146.200 139.406 1.00 73.88  ? 127  GLY   R O   1 
ATOM   1154 N  N   . THR   B 2 66  ? 168.176 146.482 137.902 1.00 76.32  ? 128  THR   R N   1 
ATOM   1155 C  CA  . THR   B 2 66  ? 169.204 146.002 138.820 1.00 76.32  ? 128  THR   R CA  1 
ATOM   1156 C  C   . THR   B 2 66  ? 169.345 146.932 140.020 1.00 76.32  ? 128  THR   R C   1 
ATOM   1157 O  O   . THR   B 2 66  ? 169.493 146.470 141.158 1.00 76.32  ? 128  THR   R O   1 
ATOM   1158 C  CB  . THR   B 2 66  ? 170.531 145.863 138.074 1.00 76.32  ? 128  THR   R CB  1 
ATOM   1159 O  OG1 . THR   B 2 66  ? 170.374 144.929 137.000 1.00 76.32  ? 128  THR   R OG1 1 
ATOM   1160 C  CG2 . THR   B 2 66  ? 171.632 145.369 139.000 1.00 76.32  ? 128  THR   R CG2 1 
ATOM   1161 N  N   . PHE   B 2 67  ? 169.269 148.245 139.787 1.00 73.60  ? 129  PHE   R N   1 
ATOM   1162 C  CA  . PHE   B 2 67  ? 169.355 149.204 140.879 1.00 73.60  ? 129  PHE   R CA  1 
ATOM   1163 C  C   . PHE   B 2 67  ? 168.186 149.052 141.843 1.00 73.60  ? 129  PHE   R C   1 
ATOM   1164 O  O   . PHE   B 2 67  ? 168.381 149.090 143.063 1.00 73.60  ? 129  PHE   R O   1 
ATOM   1165 C  CB  . PHE   B 2 67  ? 169.413 150.620 140.312 1.00 73.60  ? 129  PHE   R CB  1 
ATOM   1166 C  CG  . PHE   B 2 67  ? 170.090 151.604 141.214 1.00 73.60  ? 129  PHE   R CG  1 
ATOM   1167 C  CD1 . PHE   B 2 67  ? 171.341 151.328 141.736 1.00 73.60  ? 129  PHE   R CD1 1 
ATOM   1168 C  CD2 . PHE   B 2 67  ? 169.489 152.811 141.525 1.00 73.60  ? 129  PHE   R CD2 1 
ATOM   1169 C  CE1 . PHE   B 2 67  ? 171.976 152.230 142.562 1.00 73.60  ? 129  PHE   R CE1 1 
ATOM   1170 C  CE2 . PHE   B 2 67  ? 170.122 153.719 142.349 1.00 73.60  ? 129  PHE   R CE2 1 
ATOM   1171 C  CZ  . PHE   B 2 67  ? 171.366 153.427 142.870 1.00 73.60  ? 129  PHE   R CZ  1 
ATOM   1172 N  N   . THR   B 2 68  ? 166.970 148.856 141.316 1.00 71.20  ? 130  THR   R N   1 
ATOM   1173 C  CA  . THR   B 2 68  ? 165.810 148.631 142.179 1.00 71.20  ? 130  THR   R CA  1 
ATOM   1174 C  C   . THR   B 2 68  ? 165.966 147.365 143.005 1.00 71.20  ? 130  THR   R C   1 
ATOM   1175 O  O   . THR   B 2 68  ? 165.643 147.356 144.201 1.00 71.20  ? 130  THR   R O   1 
ATOM   1176 C  CB  . THR   B 2 68  ? 164.531 148.534 141.354 1.00 71.20  ? 130  THR   R CB  1 
ATOM   1177 O  OG1 . THR   B 2 68  ? 164.717 147.592 140.294 1.00 71.20  ? 130  THR   R OG1 1 
ATOM   1178 C  CG2 . THR   B 2 68  ? 164.165 149.864 140.778 1.00 71.20  ? 130  THR   R CG2 1 
ATOM   1179 N  N   . VAL   B 2 69  ? 166.452 146.286 142.384 1.00 71.14  ? 131  VAL   R N   1 
ATOM   1180 C  CA  . VAL   B 2 69  ? 166.620 145.027 143.107 1.00 71.14  ? 131  VAL   R CA  1 
ATOM   1181 C  C   . VAL   B 2 69  ? 167.645 145.179 144.225 1.00 71.14  ? 131  VAL   R C   1 
ATOM   1182 O  O   . VAL   B 2 69  ? 167.418 144.732 145.358 1.00 71.14  ? 131  VAL   R O   1 
ATOM   1183 C  CB  . VAL   B 2 69  ? 167.000 143.896 142.132 1.00 71.14  ? 131  VAL   R CB  1 
ATOM   1184 C  CG1 . VAL   B 2 69  ? 167.402 142.647 142.890 1.00 71.14  ? 131  VAL   R CG1 1 
ATOM   1185 C  CG2 . VAL   B 2 69  ? 165.835 143.582 141.216 1.00 71.14  ? 131  VAL   R CG2 1 
ATOM   1186 N  N   . LEU   B 2 70  ? 168.775 145.833 143.939 1.00 72.56  ? 132  LEU   R N   1 
ATOM   1187 C  CA  . LEU   B 2 70  ? 169.789 146.021 144.976 1.00 72.56  ? 132  LEU   R CA  1 
ATOM   1188 C  C   . LEU   B 2 70  ? 169.314 146.946 146.092 1.00 72.56  ? 132  LEU   R C   1 
ATOM   1189 O  O   . LEU   B 2 70  ? 169.600 146.684 147.265 1.00 72.56  ? 132  LEU   R O   1 
ATOM   1190 C  CB  . LEU   B 2 70  ? 171.110 146.510 144.378 1.00 72.56  ? 132  LEU   R CB  1 
ATOM   1191 C  CG  . LEU   B 2 70  ? 172.094 145.476 143.800 1.00 72.56  ? 132  LEU   R CG  1 
ATOM   1192 C  CD1 . LEU   B 2 70  ? 172.571 144.578 144.932 1.00 72.56  ? 132  LEU   R CD1 1 
ATOM   1193 C  CD2 . LEU   B 2 70  ? 171.563 144.610 142.677 1.00 72.56  ? 132  LEU   R CD2 1 
ATOM   1194 N  N   . GLU   B 2 71  ? 168.573 148.013 145.763 1.00 71.81  ? 133  GLU   R N   1 
ATOM   1195 C  CA  . GLU   B 2 71  ? 168.012 148.865 146.813 1.00 71.81  ? 133  GLU   R CA  1 
ATOM   1196 C  C   . GLU   B 2 71  ? 167.039 148.099 147.697 1.00 71.81  ? 133  GLU   R C   1 
ATOM   1197 O  O   . GLU   B 2 71  ? 167.047 148.253 148.925 1.00 71.81  ? 133  GLU   R O   1 
ATOM   1198 C  CB  . GLU   B 2 71  ? 167.298 150.075 146.217 1.00 71.81  ? 133  GLU   R CB  1 
ATOM   1199 C  CG  . GLU   B 2 71  ? 168.162 151.091 145.520 1.00 71.81  ? 133  GLU   R CG  1 
ATOM   1200 C  CD  . GLU   B 2 71  ? 167.329 152.221 144.961 1.00 71.81  ? 133  GLU   R CD  1 
ATOM   1201 O  OE1 . GLU   B 2 71  ? 166.090 152.117 145.022 1.00 71.81  ? 133  GLU   R OE1 1 
ATOM   1202 O  OE2 . GLU   B 2 71  ? 167.899 153.215 144.477 1.00 71.81  ? 133  GLU   R OE2 1 
ATOM   1203 N  N   . ASN   B 2 72  ? 166.199 147.265 147.091 1.00 68.53  ? 134  ASN   R N   1 
ATOM   1204 C  CA  . ASN   B 2 72  ? 165.182 146.565 147.862 1.00 68.53  ? 134  ASN   R CA  1 
ATOM   1205 C  C   . ASN   B 2 72  ? 165.799 145.496 148.753 1.00 68.53  ? 134  ASN   R C   1 
ATOM   1206 O  O   . ASN   B 2 72  ? 165.417 145.362 149.923 1.00 68.53  ? 134  ASN   R O   1 
ATOM   1207 C  CB  . ASN   B 2 72  ? 164.164 145.964 146.909 1.00 68.53  ? 134  ASN   R CB  1 
ATOM   1208 C  CG  . ASN   B 2 72  ? 163.109 146.956 146.510 1.00 68.53  ? 134  ASN   R CG  1 
ATOM   1209 O  OD1 . ASN   B 2 72  ? 163.182 148.133 146.856 1.00 68.53  ? 134  ASN   R OD1 1 
ATOM   1210 N  ND2 . ASN   B 2 72  ? 162.144 146.500 145.738 1.00 68.53  ? 134  ASN   R ND2 1 
ATOM   1211 N  N   . LEU   B 2 73  ? 166.761 144.732 148.226 1.00 71.23  ? 135  LEU   R N   1 
ATOM   1212 C  CA  . LEU   B 2 73  ? 167.479 143.786 149.075 1.00 71.23  ? 135  LEU   R CA  1 
ATOM   1213 C  C   . LEU   B 2 73  ? 168.296 144.492 150.148 1.00 71.23  ? 135  LEU   R C   1 
ATOM   1214 O  O   . LEU   B 2 73  ? 168.451 143.952 151.249 1.00 71.23  ? 135  LEU   R O   1 
ATOM   1215 C  CB  . LEU   B 2 73  ? 168.372 142.861 148.245 1.00 71.23  ? 135  LEU   R CB  1 
ATOM   1216 C  CG  . LEU   B 2 73  ? 167.780 141.603 147.589 1.00 71.23  ? 135  LEU   R CG  1 
ATOM   1217 C  CD1 . LEU   B 2 73  ? 167.297 140.650 148.674 1.00 71.23  ? 135  LEU   R CD1 1 
ATOM   1218 C  CD2 . LEU   B 2 73  ? 166.667 141.861 146.595 1.00 71.23  ? 135  LEU   R CD2 1 
ATOM   1219 N  N   . LEU   B 2 74  ? 168.801 145.697 149.866 1.00 72.33  ? 136  LEU   R N   1 
ATOM   1220 C  CA  . LEU   B 2 74  ? 169.474 146.466 150.903 1.00 72.33  ? 136  LEU   R CA  1 
ATOM   1221 C  C   . LEU   B 2 74  ? 168.514 146.836 152.024 1.00 72.33  ? 136  LEU   R C   1 
ATOM   1222 O  O   . LEU   B 2 74  ? 168.861 146.730 153.206 1.00 72.33  ? 136  LEU   R O   1 
ATOM   1223 C  CB  . LEU   B 2 74  ? 170.108 147.720 150.306 1.00 72.33  ? 136  LEU   R CB  1 
ATOM   1224 C  CG  . LEU   B 2 74  ? 171.250 148.297 151.141 1.00 72.33  ? 136  LEU   R CG  1 
ATOM   1225 C  CD1 . LEU   B 2 74  ? 172.379 147.289 151.254 1.00 72.33  ? 136  LEU   R CD1 1 
ATOM   1226 C  CD2 . LEU   B 2 74  ? 171.747 149.603 150.549 1.00 72.33  ? 136  LEU   R CD2 1 
ATOM   1227 N  N   . VAL   B 2 75  ? 167.294 147.247 151.668 1.00 72.63  ? 137  VAL   R N   1 
ATOM   1228 C  CA  . VAL   B 2 75  ? 166.297 147.608 152.674 1.00 72.63  ? 137  VAL   R CA  1 
ATOM   1229 C  C   . VAL   B 2 75  ? 165.918 146.393 153.517 1.00 72.63  ? 137  VAL   R C   1 
ATOM   1230 O  O   . VAL   B 2 75  ? 165.861 146.472 154.753 1.00 72.63  ? 137  VAL   R O   1 
ATOM   1231 C  CB  . VAL   B 2 75  ? 165.069 148.246 151.999 1.00 72.63  ? 137  VAL   R CB  1 
ATOM   1232 C  CG1 . VAL   B 2 75  ? 163.884 148.283 152.945 1.00 72.63  ? 137  VAL   R CG1 1 
ATOM   1233 C  CG2 . VAL   B 2 75  ? 165.404 149.645 151.528 1.00 72.63  ? 137  VAL   R CG2 1 
ATOM   1234 N  N   . LEU   B 2 76  ? 165.690 145.244 152.868 1.00 73.37  ? 138  LEU   R N   1 
ATOM   1235 C  CA  . LEU   B 2 76  ? 165.384 144.027 153.620 1.00 73.37  ? 138  LEU   R CA  1 
ATOM   1236 C  C   . LEU   B 2 76  ? 166.526 143.617 154.543 1.00 73.37  ? 138  LEU   R C   1 
ATOM   1237 O  O   . LEU   B 2 76  ? 166.285 143.250 155.699 1.00 73.37  ? 138  LEU   R O   1 
ATOM   1238 C  CB  . LEU   B 2 76  ? 165.033 142.861 152.693 1.00 73.37  ? 138  LEU   R CB  1 
ATOM   1239 C  CG  . LEU   B 2 76  ? 163.601 142.632 152.196 1.00 73.37  ? 138  LEU   R CG  1 
ATOM   1240 C  CD1 . LEU   B 2 76  ? 162.687 142.332 153.375 1.00 73.37  ? 138  LEU   R CD1 1 
ATOM   1241 C  CD2 . LEU   B 2 76  ? 163.057 143.771 151.393 1.00 73.37  ? 138  LEU   R CD2 1 
ATOM   1242 N  N   . CYS   B 2 77  ? 167.774 143.673 154.067 1.00 78.80  ? 139  CYS   R N   1 
ATOM   1243 C  CA  . CYS   B 2 77  ? 168.848 143.173 154.916 1.00 78.80  ? 139  CYS   R CA  1 
ATOM   1244 C  C   . CYS   B 2 77  ? 169.160 144.138 156.050 1.00 78.80  ? 139  CYS   R C   1 
ATOM   1245 O  O   . CYS   B 2 77  ? 169.590 143.699 157.121 1.00 78.80  ? 139  CYS   R O   1 
ATOM   1246 C  CB  . CYS   B 2 77  ? 170.116 142.881 154.111 1.00 78.80  ? 139  CYS   R CB  1 
ATOM   1247 S  SG  . CYS   B 2 77  ? 170.926 144.288 153.346 1.00 78.80  ? 139  CYS   R SG  1 
ATOM   1248 N  N   . VAL   B 2 78  ? 168.942 145.442 155.858 1.00 78.08  ? 140  VAL   R N   1 
ATOM   1249 C  CA  . VAL   B 2 78  ? 169.177 146.336 156.987 1.00 78.08  ? 140  VAL   R CA  1 
ATOM   1250 C  C   . VAL   B 2 78  ? 168.011 146.248 157.971 1.00 78.08  ? 140  VAL   R C   1 
ATOM   1251 O  O   . VAL   B 2 78  ? 168.191 146.486 159.171 1.00 78.08  ? 140  VAL   R O   1 
ATOM   1252 C  CB  . VAL   B 2 78  ? 169.438 147.785 156.520 1.00 78.08  ? 140  VAL   R CB  1 
ATOM   1253 C  CG1 . VAL   B 2 78  ? 168.216 148.403 155.858 1.00 78.08  ? 140  VAL   R CG1 1 
ATOM   1254 C  CG2 . VAL   B 2 78  ? 169.968 148.657 157.658 1.00 78.08  ? 140  VAL   R CG2 1 
ATOM   1255 N  N   . ILE   B 2 79  ? 166.813 145.880 157.503 1.00 76.97  ? 141  ILE   R N   1 
ATOM   1256 C  CA  . ILE   B 2 79  ? 165.712 145.642 158.432 1.00 76.97  ? 141  ILE   R CA  1 
ATOM   1257 C  C   . ILE   B 2 79  ? 165.978 144.393 159.265 1.00 76.97  ? 141  ILE   R C   1 
ATOM   1258 O  O   . ILE   B 2 79  ? 165.882 144.416 160.498 1.00 76.97  ? 141  ILE   R O   1 
ATOM   1259 C  CB  . ILE   B 2 79  ? 164.376 145.540 157.673 1.00 76.97  ? 141  ILE   R CB  1 
ATOM   1260 C  CG1 . ILE   B 2 79  ? 163.847 146.928 157.331 1.00 76.97  ? 141  ILE   R CG1 1 
ATOM   1261 C  CG2 . ILE   B 2 79  ? 163.332 144.798 158.492 1.00 76.97  ? 141  ILE   R CG2 1 
ATOM   1262 C  CD1 . ILE   B 2 79  ? 162.772 146.904 156.284 1.00 76.97  ? 141  ILE   R CD1 1 
ATOM   1263 N  N   . LEU   B 2 80  ? 166.351 143.294 158.610 1.00 78.85  ? 142  LEU   R N   1 
ATOM   1264 C  CA  . LEU   B 2 80  ? 166.478 142.019 159.305 1.00 78.85  ? 142  LEU   R CA  1 
ATOM   1265 C  C   . LEU   B 2 80  ? 167.757 141.895 160.122 1.00 78.85  ? 142  LEU   R C   1 
ATOM   1266 O  O   . LEU   B 2 80  ? 167.837 141.003 160.973 1.00 78.85  ? 142  LEU   R O   1 
ATOM   1267 C  CB  . LEU   B 2 80  ? 166.388 140.852 158.316 1.00 78.85  ? 142  LEU   R CB  1 
ATOM   1268 C  CG  . LEU   B 2 80  ? 165.010 140.312 157.904 1.00 78.85  ? 142  LEU   R CG  1 
ATOM   1269 C  CD1 . LEU   B 2 80  ? 164.319 139.685 159.107 1.00 78.85  ? 142  LEU   R CD1 1 
ATOM   1270 C  CD2 . LEU   B 2 80  ? 164.099 141.337 157.242 1.00 78.85  ? 142  LEU   R CD2 1 
ATOM   1271 N  N   . HIS   B 2 81  ? 168.751 142.750 159.896 1.00 81.04  ? 143  HIS   R N   1 
ATOM   1272 C  CA  . HIS   B 2 81  ? 169.952 142.773 160.719 1.00 81.04  ? 143  HIS   R CA  1 
ATOM   1273 C  C   . HIS   B 2 81  ? 169.847 143.774 161.859 1.00 81.04  ? 143  HIS   R C   1 
ATOM   1274 O  O   . HIS   B 2 81  ? 170.825 143.980 162.584 1.00 81.04  ? 143  HIS   R O   1 
ATOM   1275 C  CB  . HIS   B 2 81  ? 171.183 143.082 159.866 1.00 81.04  ? 143  HIS   R CB  1 
ATOM   1276 C  CG  . HIS   B 2 81  ? 171.613 141.945 158.993 1.00 81.04  ? 143  HIS   R CG  1 
ATOM   1277 N  ND1 . HIS   B 2 81  ? 172.327 142.129 157.829 1.00 81.04  ? 143  HIS   R ND1 1 
ATOM   1278 C  CD2 . HIS   B 2 81  ? 171.427 140.610 159.113 1.00 81.04  ? 143  HIS   R CD2 1 
ATOM   1279 C  CE1 . HIS   B 2 81  ? 172.564 140.956 157.270 1.00 81.04  ? 143  HIS   R CE1 1 
ATOM   1280 N  NE2 . HIS   B 2 81  ? 172.028 140.017 158.029 1.00 81.04  ? 143  HIS   R NE2 1 
ATOM   1281 N  N   . SER   B 2 82  ? 168.690 144.404 162.024 1.00 82.69  ? 144  SER   R N   1 
ATOM   1282 C  CA  . SER   B 2 82  ? 168.455 145.374 163.082 1.00 82.69  ? 144  SER   R CA  1 
ATOM   1283 C  C   . SER   B 2 82  ? 167.406 144.825 164.035 1.00 82.69  ? 144  SER   R C   1 
ATOM   1284 O  O   . SER   B 2 82  ? 166.307 144.456 163.608 1.00 82.69  ? 144  SER   R O   1 
ATOM   1285 C  CB  . SER   B 2 82  ? 167.997 146.712 162.504 1.00 82.69  ? 144  SER   R CB  1 
ATOM   1286 O  OG  . SER   B 2 82  ? 166.971 146.515 161.549 1.00 82.69  ? 144  SER   R OG  1 
ATOM   1287 N  N   . ARG   B 2 83  ? 167.749 144.770 165.324 1.00 82.56  ? 145  ARG   R N   1 
ATOM   1288 C  CA  . ARG   B 2 83  ? 166.799 144.282 166.316 1.00 82.56  ? 145  ARG   R CA  1 
ATOM   1289 C  C   . ARG   B 2 83  ? 165.714 145.309 166.610 1.00 82.56  ? 145  ARG   R C   1 
ATOM   1290 O  O   . ARG   B 2 83  ? 164.573 144.936 166.904 1.00 82.56  ? 145  ARG   R O   1 
ATOM   1291 C  CB  . ARG   B 2 83  ? 167.531 143.903 167.603 1.00 82.56  ? 145  ARG   R CB  1 
ATOM   1292 N  N   . SER   B 2 84  ? 166.044 146.597 166.530 1.00 85.22  ? 146  SER   R N   1 
ATOM   1293 C  CA  . SER   B 2 84  ? 165.112 147.641 166.932 1.00 85.22  ? 146  SER   R CA  1 
ATOM   1294 C  C   . SER   B 2 84  ? 164.092 147.986 165.856 1.00 85.22  ? 146  SER   R C   1 
ATOM   1295 O  O   . SER   B 2 84  ? 163.174 148.767 166.126 1.00 85.22  ? 146  SER   R O   1 
ATOM   1296 C  CB  . SER   B 2 84  ? 165.881 148.903 167.327 1.00 85.22  ? 146  SER   R CB  1 
ATOM   1297 O  OG  . SER   B 2 84  ? 164.991 149.949 167.674 1.00 85.22  ? 146  SER   R OG  1 
ATOM   1298 N  N   . LEU   B 2 85  ? 164.225 147.436 164.651 1.00 83.14  ? 147  LEU   R N   1 
ATOM   1299 C  CA  . LEU   B 2 85  ? 163.321 147.817 163.572 1.00 83.14  ? 147  LEU   R CA  1 
ATOM   1300 C  C   . LEU   B 2 85  ? 162.203 146.806 163.352 1.00 83.14  ? 147  LEU   R C   1 
ATOM   1301 O  O   . LEU   B 2 85  ? 161.062 147.201 163.093 1.00 83.14  ? 147  LEU   R O   1 
ATOM   1302 C  CB  . LEU   B 2 85  ? 164.106 148.019 162.275 1.00 83.14  ? 147  LEU   R CB  1 
ATOM   1303 C  CG  . LEU   B 2 85  ? 165.035 149.234 162.213 1.00 83.14  ? 147  LEU   R CG  1 
ATOM   1304 C  CD1 . LEU   B 2 85  ? 165.299 149.618 160.769 1.00 83.14  ? 147  LEU   R CD1 1 
ATOM   1305 C  CD2 . LEU   B 2 85  ? 164.472 150.420 162.986 1.00 83.14  ? 147  LEU   R CD2 1 
ATOM   1306 N  N   . ARG   B 2 86  ? 162.496 145.510 163.435 1.00 81.54  ? 148  ARG   R N   1 
ATOM   1307 C  CA  . ARG   B 2 86  ? 161.443 144.514 163.303 1.00 81.54  ? 148  ARG   R CA  1 
ATOM   1308 C  C   . ARG   B 2 86  ? 160.731 144.229 164.618 1.00 81.54  ? 148  ARG   R C   1 
ATOM   1309 O  O   . ARG   B 2 86  ? 159.693 143.559 164.609 1.00 81.54  ? 148  ARG   R O   1 
ATOM   1310 C  CB  . ARG   B 2 86  ? 162.000 143.209 162.722 1.00 81.54  ? 148  ARG   R CB  1 
ATOM   1311 C  CG  . ARG   B 2 86  ? 163.319 142.747 163.309 1.00 81.54  ? 148  ARG   R CG  1 
ATOM   1312 C  CD  . ARG   B 2 86  ? 163.425 141.216 163.242 1.00 81.54  ? 148  ARG   R CD  1 
ATOM   1313 N  NE  . ARG   B 2 86  ? 164.784 140.687 163.352 1.00 81.54  ? 148  ARG   R NE  1 
ATOM   1314 C  CZ  . ARG   B 2 86  ? 165.604 140.840 164.386 1.00 81.54  ? 148  ARG   R CZ  1 
ATOM   1315 N  NH1 . ARG   B 2 86  ? 165.206 141.397 165.519 1.00 81.54  ? 148  ARG   R NH1 1 
ATOM   1316 N  NH2 . ARG   B 2 86  ? 166.849 140.384 164.295 1.00 81.54  ? 148  ARG   R NH2 1 
ATOM   1317 N  N   . CYS   B 2 87  ? 161.253 144.721 165.741 1.00 84.78  ? 149  CYS   R N   1 
ATOM   1318 C  CA  . CYS   B 2 87  ? 160.541 144.611 167.006 1.00 84.78  ? 149  CYS   R CA  1 
ATOM   1319 C  C   . CYS   B 2 87  ? 159.463 145.673 167.162 1.00 84.78  ? 149  CYS   R C   1 
ATOM   1320 O  O   . CYS   B 2 87  ? 158.601 145.535 168.037 1.00 84.78  ? 149  CYS   R O   1 
ATOM   1321 C  CB  . CYS   B 2 87  ? 161.519 144.701 168.179 1.00 84.78  ? 149  CYS   R CB  1 
ATOM   1322 S  SG  . CYS   B 2 87  ? 162.055 146.378 168.571 1.00 84.78  ? 149  CYS   R SG  1 
ATOM   1323 N  N   . ARG   B 2 88  ? 159.490 146.722 166.341 1.00 79.31  ? 150  ARG   R N   1 
ATOM   1324 C  CA  . ARG   B 2 88  ? 158.456 147.742 166.360 1.00 79.31  ? 150  ARG   R CA  1 
ATOM   1325 C  C   . ARG   B 2 88  ? 157.469 147.469 165.241 1.00 79.31  ? 150  ARG   R C   1 
ATOM   1326 O  O   . ARG   B 2 88  ? 157.876 147.444 164.069 1.00 79.31  ? 150  ARG   R O   1 
ATOM   1327 C  CB  . ARG   B 2 88  ? 159.067 149.128 166.200 1.00 79.31  ? 150  ARG   R CB  1 
ATOM   1328 C  CG  . ARG   B 2 88  ? 159.817 149.609 167.427 1.00 79.31  ? 150  ARG   R CG  1 
ATOM   1329 C  CD  . ARG   B 2 88  ? 160.205 151.071 167.308 1.00 79.31  ? 150  ARG   R CD  1 
ATOM   1330 N  NE  . ARG   B 2 88  ? 161.409 151.260 166.509 1.00 79.31  ? 150  ARG   R NE  1 
ATOM   1331 C  CZ  . ARG   B 2 88  ? 161.986 152.435 166.298 1.00 79.31  ? 150  ARG   R CZ  1 
ATOM   1332 N  NH1 . ARG   B 2 88  ? 161.486 153.551 166.802 1.00 79.31  ? 150  ARG   R NH1 1 
ATOM   1333 N  NH2 . ARG   B 2 88  ? 163.094 152.492 165.565 1.00 79.31  ? 150  ARG   R NH2 1 
ATOM   1334 N  N   . PRO   B 2 89  ? 156.189 147.234 165.543 1.00 72.15  ? 151  PRO   R N   1 
ATOM   1335 C  CA  . PRO   B 2 89  ? 155.211 146.994 164.467 1.00 72.15  ? 151  PRO   R CA  1 
ATOM   1336 C  C   . PRO   B 2 89  ? 155.014 148.182 163.545 1.00 72.15  ? 151  PRO   R C   1 
ATOM   1337 O  O   . PRO   B 2 89  ? 154.667 147.992 162.372 1.00 72.15  ? 151  PRO   R O   1 
ATOM   1338 C  CB  . PRO   B 2 89  ? 153.925 146.659 165.235 1.00 72.15  ? 151  PRO   R CB  1 
ATOM   1339 C  CG  . PRO   B 2 89  ? 154.111 147.283 166.573 1.00 72.15  ? 151  PRO   R CG  1 
ATOM   1340 C  CD  . PRO   B 2 89  ? 155.572 147.181 166.877 1.00 72.15  ? 151  PRO   R CD  1 
ATOM   1341 N  N   . SER   B 2 90  ? 155.262 149.400 164.036 1.00 65.75  ? 152  SER   R N   1 
ATOM   1342 C  CA  . SER   B 2 90  ? 155.071 150.607 163.240 1.00 65.75  ? 152  SER   R CA  1 
ATOM   1343 C  C   . SER   B 2 90  ? 155.993 150.670 162.031 1.00 65.75  ? 152  SER   R C   1 
ATOM   1344 O  O   . SER   B 2 90  ? 155.688 151.388 161.074 1.00 65.75  ? 152  SER   R O   1 
ATOM   1345 C  CB  . SER   B 2 90  ? 155.291 151.838 164.113 1.00 65.75  ? 152  SER   R CB  1 
ATOM   1346 O  OG  . SER   B 2 90  ? 156.501 151.737 164.843 1.00 65.75  ? 152  SER   R OG  1 
ATOM   1347 N  N   . TYR   B 2 91  ? 157.108 149.947 162.053 1.00 71.44  ? 153  TYR   R N   1 
ATOM   1348 C  CA  . TYR   B 2 91  ? 158.020 149.885 160.923 1.00 71.44  ? 153  TYR   R CA  1 
ATOM   1349 C  C   . TYR   B 2 91  ? 157.795 148.666 160.040 1.00 71.44  ? 153  TYR   R C   1 
ATOM   1350 O  O   . TYR   B 2 91  ? 158.431 148.568 158.983 1.00 71.44  ? 153  TYR   R O   1 
ATOM   1351 C  CB  . TYR   B 2 91  ? 159.466 149.900 161.419 1.00 71.44  ? 153  TYR   R CB  1 
ATOM   1352 C  CG  . TYR   B 2 91  ? 160.031 151.287 161.577 1.00 71.44  ? 153  TYR   R CG  1 
ATOM   1353 C  CD1 . TYR   B 2 91  ? 159.833 152.249 160.598 1.00 71.44  ? 153  TYR   R CD1 1 
ATOM   1354 C  CD2 . TYR   B 2 91  ? 160.760 151.637 162.703 1.00 71.44  ? 153  TYR   R CD2 1 
ATOM   1355 C  CE1 . TYR   B 2 91  ? 160.346 153.521 160.734 1.00 71.44  ? 153  TYR   R CE1 1 
ATOM   1356 C  CE2 . TYR   B 2 91  ? 161.278 152.908 162.849 1.00 71.44  ? 153  TYR   R CE2 1 
ATOM   1357 C  CZ  . TYR   B 2 91  ? 161.068 153.845 161.861 1.00 71.44  ? 153  TYR   R CZ  1 
ATOM   1358 O  OH  . TYR   B 2 91  ? 161.583 155.113 161.999 1.00 71.44  ? 153  TYR   R OH  1 
ATOM   1359 N  N   . HIS   B 2 92  ? 156.882 147.763 160.433 1.00 71.48  ? 154  HIS   R N   1 
ATOM   1360 C  CA  . HIS   B 2 92  ? 156.743 146.470 159.763 1.00 71.48  ? 154  HIS   R CA  1 
ATOM   1361 C  C   . HIS   B 2 92  ? 156.407 146.636 158.289 1.00 71.48  ? 154  HIS   R C   1 
ATOM   1362 O  O   . HIS   B 2 92  ? 157.008 145.980 157.425 1.00 71.48  ? 154  HIS   R O   1 
ATOM   1363 C  CB  . HIS   B 2 92  ? 155.659 145.641 160.450 1.00 71.48  ? 154  HIS   R CB  1 
ATOM   1364 C  CG  . HIS   B 2 92  ? 156.148 144.856 161.624 1.00 71.48  ? 154  HIS   R CG  1 
ATOM   1365 N  ND1 . HIS   B 2 92  ? 155.383 143.891 162.243 1.00 71.48  ? 154  HIS   R ND1 1 
ATOM   1366 C  CD2 . HIS   B 2 92  ? 157.324 144.891 162.293 1.00 71.48  ? 154  HIS   R CD2 1 
ATOM   1367 C  CE1 . HIS   B 2 92  ? 156.066 143.367 163.244 1.00 71.48  ? 154  HIS   R CE1 1 
ATOM   1368 N  NE2 . HIS   B 2 92  ? 157.247 143.956 163.296 1.00 71.48  ? 154  HIS   R NE2 1 
ATOM   1369 N  N   . PHE   B 2 93  ? 155.497 147.564 157.988 1.00 64.24  ? 155  PHE   R N   1 
ATOM   1370 C  CA  . PHE   B 2 93  ? 155.052 147.795 156.621 1.00 64.24  ? 155  PHE   R CA  1 
ATOM   1371 C  C   . PHE   B 2 93  ? 156.194 148.212 155.702 1.00 64.24  ? 155  PHE   R C   1 
ATOM   1372 O  O   . PHE   B 2 93  ? 156.113 147.955 154.492 1.00 64.24  ? 155  PHE   R O   1 
ATOM   1373 C  CB  . PHE   B 2 93  ? 153.961 148.859 156.605 1.00 64.24  ? 155  PHE   R CB  1 
ATOM   1374 C  CG  . PHE   B 2 93  ? 154.490 150.241 156.689 1.00 64.24  ? 155  PHE   R CG  1 
ATOM   1375 C  CD1 . PHE   B 2 93  ? 155.067 150.701 157.858 1.00 64.24  ? 155  PHE   R CD1 1 
ATOM   1376 C  CD2 . PHE   B 2 93  ? 154.437 151.077 155.595 1.00 64.24  ? 155  PHE   R CD2 1 
ATOM   1377 C  CE1 . PHE   B 2 93  ? 155.572 151.962 157.931 1.00 64.24  ? 155  PHE   R CE1 1 
ATOM   1378 C  CE2 . PHE   B 2 93  ? 154.942 152.340 155.669 1.00 64.24  ? 155  PHE   R CE2 1 
ATOM   1379 C  CZ  . PHE   B 2 93  ? 155.508 152.773 156.837 1.00 64.24  ? 155  PHE   R CZ  1 
ATOM   1380 N  N   . ILE   B 2 94  ? 157.249 148.850 156.250 1.00 65.91  ? 156  ILE   R N   1 
ATOM   1381 C  CA  . ILE   B 2 94  ? 158.453 149.145 155.465 1.00 65.91  ? 156  ILE   R CA  1 
ATOM   1382 C  C   . ILE   B 2 94  ? 158.934 147.899 154.748 1.00 65.91  ? 156  ILE   R C   1 
ATOM   1383 O  O   . ILE   B 2 94  ? 159.008 147.874 153.510 1.00 65.91  ? 156  ILE   R O   1 
ATOM   1384 C  CB  . ILE   B 2 94  ? 159.568 149.734 156.349 1.00 65.91  ? 156  ILE   R CB  1 
ATOM   1385 C  CG1 . ILE   B 2 94  ? 159.133 151.034 157.015 1.00 65.91  ? 156  ILE   R CG1 1 
ATOM   1386 C  CG2 . ILE   B 2 94  ? 160.816 149.975 155.524 1.00 65.91  ? 156  ILE   R CG2 1 
ATOM   1387 C  CD1 . ILE   B 2 94  ? 158.804 152.106 156.011 1.00 65.91  ? 156  ILE   R CD1 1 
ATOM   1388 N  N   . GLY   B 2 95  ? 159.156 146.820 155.509 1.00 63.44  ? 157  GLY   R N   1 
ATOM   1389 C  CA  . GLY   B 2 95  ? 159.536 145.560 154.898 1.00 63.44  ? 157  GLY   R CA  1 
ATOM   1390 C  C   . GLY   B 2 95  ? 158.514 145.105 153.881 1.00 63.44  ? 157  GLY   R C   1 
ATOM   1391 O  O   . GLY   B 2 95  ? 158.864 144.833 152.726 1.00 63.44  ? 157  GLY   R O   1 
ATOM   1392 N  N   . SER   B 2 96  ? 157.229 145.175 154.258 1.00 61.82  ? 158  SER   R N   1 
ATOM   1393 C  CA  . SER   B 2 96  ? 156.146 144.807 153.354 1.00 61.82  ? 158  SER   R CA  1 
ATOM   1394 C  C   . SER   B 2 96  ? 156.209 145.623 152.076 1.00 61.82  ? 158  SER   R C   1 
ATOM   1395 O  O   . SER   B 2 96  ? 156.218 145.056 150.973 1.00 61.82  ? 158  SER   R O   1 
ATOM   1396 C  CB  . SER   B 2 96  ? 154.798 145.002 154.045 1.00 61.82  ? 158  SER   R CB  1 
ATOM   1397 O  OG  . SER   B 2 96  ? 153.735 144.885 153.117 1.00 61.82  ? 158  SER   R OG  1 
ATOM   1398 N  N   . LEU   B 2 97  ? 156.386 146.945 152.216 1.00 58.35  ? 159  LEU   R N   1 
ATOM   1399 C  CA  . LEU   B 2 97  ? 156.420 147.809 151.043 1.00 58.35  ? 159  LEU   R CA  1 
ATOM   1400 C  C   . LEU   B 2 97  ? 157.572 147.424 150.139 1.00 58.35  ? 159  LEU   R C   1 
ATOM   1401 O  O   . LEU   B 2 97  ? 157.381 147.224 148.930 1.00 58.35  ? 159  LEU   R O   1 
ATOM   1402 C  CB  . LEU   B 2 97  ? 156.536 149.273 151.456 1.00 58.35  ? 159  LEU   R CB  1 
ATOM   1403 C  CG  . LEU   B 2 97  ? 155.244 150.077 151.582 1.00 58.35  ? 159  LEU   R CG  1 
ATOM   1404 C  CD1 . LEU   B 2 97  ? 155.519 151.423 152.214 1.00 58.35  ? 159  LEU   R CD1 1 
ATOM   1405 C  CD2 . LEU   B 2 97  ? 154.609 150.261 150.232 1.00 58.35  ? 159  LEU   R CD2 1 
ATOM   1406 N  N   . ALA   B 2 98  ? 158.740 147.174 150.739 1.00 58.46  ? 160  ALA   R N   1 
ATOM   1407 C  CA  . ALA   B 2 98  ? 159.907 146.824 149.948 1.00 58.46  ? 160  ALA   R CA  1 
ATOM   1408 C  C   . ALA   B 2 98  ? 159.688 145.501 149.238 1.00 58.46  ? 160  ALA   R C   1 
ATOM   1409 O  O   . ALA   B 2 98  ? 159.979 145.382 148.039 1.00 58.46  ? 160  ALA   R O   1 
ATOM   1410 C  CB  . ALA   B 2 98  ? 161.144 146.781 150.837 1.00 58.46  ? 160  ALA   R CB  1 
ATOM   1411 N  N   . VAL   B 2 99  ? 159.056 144.543 149.931 1.00 55.60  ? 161  VAL   R N   1 
ATOM   1412 C  CA  . VAL   B 2 99  ? 158.786 143.244 149.327 1.00 55.60  ? 161  VAL   R CA  1 
ATOM   1413 C  C   . VAL   B 2 99  ? 157.865 143.415 148.133 1.00 55.60  ? 161  VAL   R C   1 
ATOM   1414 O  O   . VAL   B 2 99  ? 158.106 142.842 147.061 1.00 55.60  ? 161  VAL   R O   1 
ATOM   1415 C  CB  . VAL   B 2 99  ? 158.203 142.273 150.371 1.00 55.60  ? 161  VAL   R CB  1 
ATOM   1416 C  CG1 . VAL   B 2 99  ? 157.634 141.036 149.701 1.00 55.60  ? 161  VAL   R CG1 1 
ATOM   1417 C  CG2 . VAL   B 2 99  ? 159.270 141.874 151.364 1.00 55.60  ? 161  VAL   R CG2 1 
ATOM   1418 N  N   . ALA   B 2 100 ? 156.858 144.286 148.268 1.00 56.65  ? 162  ALA   R N   1 
ATOM   1419 C  CA  . ALA   B 2 100 ? 155.952 144.527 147.155 1.00 56.65  ? 162  ALA   R CA  1 
ATOM   1420 C  C   . ALA   B 2 100 ? 156.702 145.130 145.982 1.00 56.65  ? 162  ALA   R C   1 
ATOM   1421 O  O   . ALA   B 2 100 ? 156.540 144.683 144.838 1.00 56.65  ? 162  ALA   R O   1 
ATOM   1422 C  CB  . ALA   B 2 100 ? 154.806 145.430 147.594 1.00 56.65  ? 162  ALA   R CB  1 
ATOM   1423 N  N   . ASP   B 2 101 ? 157.608 146.071 146.266 1.00 62.72  ? 163  ASP   R N   1 
ATOM   1424 C  CA  . ASP   B 2 101 ? 158.395 146.668 145.198 1.00 62.72  ? 163  ASP   R CA  1 
ATOM   1425 C  C   . ASP   B 2 101 ? 159.313 145.638 144.563 1.00 62.72  ? 163  ASP   R C   1 
ATOM   1426 O  O   . ASP   B 2 101 ? 159.555 145.691 143.351 1.00 62.72  ? 163  ASP   R O   1 
ATOM   1427 C  CB  . ASP   B 2 101 ? 159.193 147.853 145.734 1.00 62.72  ? 163  ASP   R CB  1 
ATOM   1428 C  CG  . ASP   B 2 101 ? 158.322 149.040 146.061 1.00 62.72  ? 163  ASP   R CG  1 
ATOM   1429 O  OD1 . ASP   B 2 101 ? 157.277 149.202 145.404 1.00 62.72  ? 163  ASP   R OD1 1 
ATOM   1430 O  OD2 . ASP   B 2 101 ? 158.682 149.809 146.976 1.00 62.72  ? 163  ASP   R OD2 1 
ATOM   1431 N  N   . LEU   B 2 102 ? 159.771 144.660 145.353 1.00 60.26  ? 164  LEU   R N   1 
ATOM   1432 C  CA  . LEU   B 2 102 ? 160.603 143.597 144.805 1.00 60.26  ? 164  LEU   R CA  1 
ATOM   1433 C  C   . LEU   B 2 102 ? 159.824 142.773 143.795 1.00 60.26  ? 164  LEU   R C   1 
ATOM   1434 O  O   . LEU   B 2 102 ? 160.366 142.374 142.758 1.00 60.26  ? 164  LEU   R O   1 
ATOM   1435 C  CB  . LEU   B 2 102 ? 161.133 142.715 145.931 1.00 60.26  ? 164  LEU   R CB  1 
ATOM   1436 C  CG  . LEU   B 2 102 ? 162.407 141.937 145.625 1.00 60.26  ? 164  LEU   R CG  1 
ATOM   1437 C  CD1 . LEU   B 2 102 ? 163.441 142.856 145.012 1.00 60.26  ? 164  LEU   R CD1 1 
ATOM   1438 C  CD2 . LEU   B 2 102 ? 162.943 141.293 146.888 1.00 60.26  ? 164  LEU   R CD2 1 
ATOM   1439 N  N   . LEU   B 2 103 ? 158.529 142.564 144.052 1.00 61.35  ? 165  LEU   R N   1 
ATOM   1440 C  CA  . LEU   B 2 103 ? 157.708 141.822 143.105 1.00 61.35  ? 165  LEU   R CA  1 
ATOM   1441 C  C   . LEU   B 2 103 ? 157.521 142.599 141.811 1.00 61.35  ? 165  LEU   R C   1 
ATOM   1442 O  O   . LEU   B 2 103 ? 157.233 142.004 140.768 1.00 61.35  ? 165  LEU   R O   1 
ATOM   1443 C  CB  . LEU   B 2 103 ? 156.359 141.487 143.737 1.00 61.35  ? 165  LEU   R CB  1 
ATOM   1444 C  CG  . LEU   B 2 103 ? 155.602 140.294 143.162 1.00 61.35  ? 165  LEU   R CG  1 
ATOM   1445 C  CD1 . LEU   B 2 103 ? 156.514 139.091 143.061 1.00 61.35  ? 165  LEU   R CD1 1 
ATOM   1446 C  CD2 . LEU   B 2 103 ? 154.401 139.980 144.029 1.00 61.35  ? 165  LEU   R CD2 1 
ATOM   1447 N  N   . GLY   B 2 104 ? 157.689 143.921 141.852 1.00 63.47  ? 166  GLY   R N   1 
ATOM   1448 C  CA  . GLY   B 2 104 ? 157.679 144.684 140.622 1.00 63.47  ? 166  GLY   R CA  1 
ATOM   1449 C  C   . GLY   B 2 104 ? 159.039 144.770 139.972 1.00 63.47  ? 166  GLY   R C   1 
ATOM   1450 O  O   . GLY   B 2 104 ? 159.139 145.070 138.781 1.00 63.47  ? 166  GLY   R O   1 
ATOM   1451 N  N   . SER   B 2 105 ? 160.102 144.519 140.733 1.00 65.20  ? 167  SER   R N   1 
ATOM   1452 C  CA  . SER   B 2 105 ? 161.437 144.673 140.169 1.00 65.20  ? 167  SER   R CA  1 
ATOM   1453 C  C   . SER   B 2 105 ? 161.872 143.412 139.434 1.00 65.20  ? 167  SER   R C   1 
ATOM   1454 O  O   . SER   B 2 105 ? 162.038 143.423 138.208 1.00 65.20  ? 167  SER   R O   1 
ATOM   1455 C  CB  . SER   B 2 105 ? 162.432 145.025 141.275 1.00 65.20  ? 167  SER   R CB  1 
ATOM   1456 O  OG  . SER   B 2 105 ? 162.000 146.160 142.000 1.00 65.20  ? 167  SER   R OG  1 
ATOM   1457 N  N   . VAL   B 2 106 ? 161.998 142.307 140.178 1.00 63.95  ? 168  VAL   R N   1 
ATOM   1458 C  CA  . VAL   B 2 106 ? 162.603 141.079 139.667 1.00 63.95  ? 168  VAL   R CA  1 
ATOM   1459 C  C   . VAL   B 2 106 ? 161.820 140.547 138.478 1.00 63.95  ? 168  VAL   R C   1 
ATOM   1460 O  O   . VAL   B 2 106 ? 162.404 140.211 137.438 1.00 63.95  ? 168  VAL   R O   1 
ATOM   1461 C  CB  . VAL   B 2 106 ? 162.703 140.035 140.795 1.00 63.95  ? 168  VAL   R CB  1 
ATOM   1462 C  CG1 . VAL   B 2 106 ? 163.051 138.669 140.238 1.00 63.95  ? 168  VAL   R CG1 1 
ATOM   1463 C  CG2 . VAL   B 2 106 ? 163.730 140.467 141.823 1.00 63.95  ? 168  VAL   R CG2 1 
ATOM   1464 N  N   . ILE   B 2 107 ? 160.486 140.540 138.594 1.00 64.45  ? 169  ILE   R N   1 
ATOM   1465 C  CA  . ILE   B 2 107 ? 159.610 140.102 137.508 1.00 64.45  ? 169  ILE   R CA  1 
ATOM   1466 C  C   . ILE   B 2 107 ? 159.909 140.886 136.240 1.00 64.45  ? 169  ILE   R C   1 
ATOM   1467 O  O   . ILE   B 2 107 ? 160.124 140.299 135.170 1.00 64.45  ? 169  ILE   R O   1 
ATOM   1468 C  CB  . ILE   B 2 107 ? 158.134 140.250 137.921 1.00 64.45  ? 169  ILE   R CB  1 
ATOM   1469 C  CG1 . ILE   B 2 107 ? 157.705 139.086 138.811 1.00 64.45  ? 169  ILE   R CG1 1 
ATOM   1470 C  CG2 . ILE   B 2 107 ? 157.231 140.344 136.701 1.00 64.45  ? 169  ILE   R CG2 1 
ATOM   1471 C  CD1 . ILE   B 2 107 ? 156.259 139.159 139.245 1.00 64.45  ? 169  ILE   R CD1 1 
ATOM   1472 N  N   . PHE   B 2 108 ? 160.033 142.214 136.376 1.00 67.78  ? 170  PHE   R N   1 
ATOM   1473 C  CA  . PHE   B 2 108 ? 160.365 143.070 135.242 1.00 67.78  ? 170  PHE   R CA  1 
ATOM   1474 C  C   . PHE   B 2 108 ? 161.665 142.627 134.599 1.00 67.78  ? 170  PHE   R C   1 
ATOM   1475 O  O   . PHE   B 2 108 ? 161.711 142.362 133.390 1.00 67.78  ? 170  PHE   R O   1 
ATOM   1476 C  CB  . PHE   B 2 108 ? 160.472 144.522 135.698 1.00 67.78  ? 170  PHE   R CB  1 
ATOM   1477 C  CG  . PHE   B 2 108 ? 161.125 145.424 134.697 1.00 67.78  ? 170  PHE   R CG  1 
ATOM   1478 C  CD1 . PHE   B 2 108 ? 160.473 145.762 133.527 1.00 67.78  ? 170  PHE   R CD1 1 
ATOM   1479 C  CD2 . PHE   B 2 108 ? 162.385 145.943 134.930 1.00 67.78  ? 170  PHE   R CD2 1 
ATOM   1480 C  CE1 . PHE   B 2 108 ? 161.067 146.595 132.606 1.00 67.78  ? 170  PHE   R CE1 1 
ATOM   1481 C  CE2 . PHE   B 2 108 ? 162.984 146.776 134.011 1.00 67.78  ? 170  PHE   R CE2 1 
ATOM   1482 C  CZ  . PHE   B 2 108 ? 162.324 147.101 132.849 1.00 67.78  ? 170  PHE   R CZ  1 
ATOM   1483 N  N   . VAL   B 2 109 ? 162.700 142.433 135.426 1.00 68.27  ? 171  VAL   R N   1 
ATOM   1484 C  CA  . VAL   B 2 109 ? 163.996 141.991 134.928 1.00 68.27  ? 171  VAL   R CA  1 
ATOM   1485 C  C   . VAL   B 2 109 ? 163.854 140.642 134.248 1.00 68.27  ? 171  VAL   R C   1 
ATOM   1486 O  O   . VAL   B 2 109 ? 164.329 140.451 133.120 1.00 68.27  ? 171  VAL   R O   1 
ATOM   1487 C  CB  . VAL   B 2 109 ? 165.021 141.954 136.076 1.00 68.27  ? 171  VAL   R CB  1 
ATOM   1488 C  CG1 . VAL   B 2 109 ? 166.222 141.103 135.707 1.00 68.27  ? 171  VAL   R CG1 1 
ATOM   1489 C  CG2 . VAL   B 2 109 ? 165.456 143.362 136.430 1.00 68.27  ? 171  VAL   R CG2 1 
ATOM   1490 N  N   . TYR   B 2 110 ? 163.102 139.727 134.874 1.00 70.43  ? 172  TYR   R N   1 
ATOM   1491 C  CA  . TYR   B 2 110 ? 162.866 138.422 134.274 1.00 70.43  ? 172  TYR   R CA  1 
ATOM   1492 C  C   . TYR   B 2 110 ? 162.144 138.573 132.949 1.00 70.43  ? 172  TYR   R C   1 
ATOM   1493 O  O   . TYR   B 2 110 ? 162.585 138.031 131.927 1.00 70.43  ? 172  TYR   R O   1 
ATOM   1494 C  CB  . TYR   B 2 110 ? 162.065 137.546 135.236 1.00 70.43  ? 172  TYR   R CB  1 
ATOM   1495 C  CG  . TYR   B 2 110 ? 161.617 136.224 134.661 1.00 70.43  ? 172  TYR   R CG  1 
ATOM   1496 C  CD1 . TYR   B 2 110 ? 162.515 135.182 134.479 1.00 70.43  ? 172  TYR   R CD1 1 
ATOM   1497 C  CD2 . TYR   B 2 110 ? 160.289 136.014 134.312 1.00 70.43  ? 172  TYR   R CD2 1 
ATOM   1498 C  CE1 . TYR   B 2 110 ? 162.107 133.970 133.958 1.00 70.43  ? 172  TYR   R CE1 1 
ATOM   1499 C  CE2 . TYR   B 2 110 ? 159.872 134.807 133.791 1.00 70.43  ? 172  TYR   R CE2 1 
ATOM   1500 C  CZ  . TYR   B 2 110 ? 160.785 133.788 133.617 1.00 70.43  ? 172  TYR   R CZ  1 
ATOM   1501 O  OH  . TYR   B 2 110 ? 160.373 132.583 133.097 1.00 70.43  ? 172  TYR   R OH  1 
ATOM   1502 N  N   . SER   B 2 111 ? 161.111 139.416 132.924 1.00 73.30  ? 173  SER   R N   1 
ATOM   1503 C  CA  . SER   B 2 111 ? 160.368 139.624 131.696 1.00 73.30  ? 173  SER   R CA  1 
ATOM   1504 C  C   . SER   B 2 111 ? 161.203 140.322 130.638 1.00 73.30  ? 173  SER   R C   1 
ATOM   1505 O  O   . SER   B 2 111 ? 160.909 140.180 129.448 1.00 73.30  ? 173  SER   R O   1 
ATOM   1506 C  CB  . SER   B 2 111 ? 159.104 140.427 131.987 1.00 73.30  ? 173  SER   R CB  1 
ATOM   1507 O  OG  . SER   B 2 111 ? 159.424 141.775 132.278 1.00 73.30  ? 173  SER   R OG  1 
ATOM   1508 N  N   . PHE   B 2 112 ? 162.263 141.021 131.035 1.00 75.10  ? 174  PHE   R N   1 
ATOM   1509 C  CA  . PHE   B 2 112 ? 163.108 141.687 130.064 1.00 75.10  ? 174  PHE   R CA  1 
ATOM   1510 C  C   . PHE   B 2 112 ? 164.156 140.753 129.476 1.00 75.10  ? 174  PHE   R C   1 
ATOM   1511 O  O   . PHE   B 2 112 ? 164.726 141.068 128.427 1.00 75.10  ? 174  PHE   R O   1 
ATOM   1512 C  CB  . PHE   B 2 112 ? 163.781 142.896 130.715 1.00 75.10  ? 174  PHE   R CB  1 
ATOM   1513 C  CG  . PHE   B 2 112 ? 164.404 143.843 129.739 1.00 75.10  ? 174  PHE   R CG  1 
ATOM   1514 C  CD1 . PHE   B 2 112 ? 163.619 144.766 129.069 1.00 75.10  ? 174  PHE   R CD1 1 
ATOM   1515 C  CD2 . PHE   B 2 112 ? 165.767 143.824 129.497 1.00 75.10  ? 174  PHE   R CD2 1 
ATOM   1516 C  CE1 . PHE   B 2 112 ? 164.177 145.652 128.178 1.00 75.10  ? 174  PHE   R CE1 1 
ATOM   1517 C  CE2 . PHE   B 2 112 ? 166.332 144.702 128.597 1.00 75.10  ? 174  PHE   R CE2 1 
ATOM   1518 C  CZ  . PHE   B 2 112 ? 165.532 145.615 127.934 1.00 75.10  ? 174  PHE   R CZ  1 
ATOM   1519 N  N   . ILE   B 2 113 ? 164.399 139.602 130.096 1.00 74.70  ? 175  ILE   R N   1 
ATOM   1520 C  CA  . ILE   B 2 113 ? 165.389 138.657 129.595 1.00 74.70  ? 175  ILE   R CA  1 
ATOM   1521 C  C   . ILE   B 2 113 ? 164.778 137.690 128.592 1.00 74.70  ? 175  ILE   R C   1 
ATOM   1522 O  O   . ILE   B 2 113 ? 165.413 137.334 127.598 1.00 74.70  ? 175  ILE   R O   1 
ATOM   1523 C  CB  . ILE   B 2 113 ? 166.058 137.910 130.771 1.00 74.70  ? 175  ILE   R CB  1 
ATOM   1524 C  CG1 . ILE   B 2 113 ? 166.767 138.902 131.688 1.00 74.70  ? 175  ILE   R CG1 1 
ATOM   1525 C  CG2 . ILE   B 2 113 ? 167.051 136.873 130.287 1.00 74.70  ? 175  ILE   R CG2 1 
ATOM   1526 C  CD1 . ILE   B 2 113 ? 167.862 139.673 131.003 1.00 74.70  ? 175  ILE   R CD1 1 
ATOM   1527 N  N   . ASP   B 2 114 ? 163.524 137.302 128.805 1.00 80.01  ? 176  ASP   R N   1 
ATOM   1528 C  CA  . ASP   B 2 114 ? 162.882 136.322 127.944 1.00 80.01  ? 176  ASP   R CA  1 
ATOM   1529 C  C   . ASP   B 2 114 ? 162.497 136.870 126.577 1.00 80.01  ? 176  ASP   R C   1 
ATOM   1530 O  O   . ASP   B 2 114 ? 162.047 136.090 125.732 1.00 80.01  ? 176  ASP   R O   1 
ATOM   1531 C  CB  . ASP   B 2 114 ? 161.643 135.759 128.632 1.00 80.01  ? 176  ASP   R CB  1 
ATOM   1532 C  CG  . ASP   B 2 114 ? 161.926 135.301 130.040 1.00 80.01  ? 176  ASP   R CG  1 
ATOM   1533 O  OD1 . ASP   B 2 114 ? 163.116 135.157 130.387 1.00 80.01  ? 176  ASP   R OD1 1 
ATOM   1534 O  OD2 . ASP   B 2 114 ? 160.960 135.082 130.798 1.00 80.01  ? 176  ASP   R OD2 1 
ATOM   1535 N  N   . PHE   B 2 115 ? 162.644 138.169 126.328 1.00 86.54  ? 177  PHE   R N   1 
ATOM   1536 C  CA  . PHE   B 2 115 ? 162.251 138.702 125.032 1.00 86.54  ? 177  PHE   R CA  1 
ATOM   1537 C  C   . PHE   B 2 115 ? 163.414 139.287 124.238 1.00 86.54  ? 177  PHE   R C   1 
ATOM   1538 O  O   . PHE   B 2 115 ? 163.388 139.227 123.007 1.00 86.54  ? 177  PHE   R O   1 
ATOM   1539 C  CB  . PHE   B 2 115 ? 161.132 139.742 125.212 1.00 86.54  ? 177  PHE   R CB  1 
ATOM   1540 C  CG  . PHE   B 2 115 ? 160.927 140.652 124.033 1.00 86.54  ? 177  PHE   R CG  1 
ATOM   1541 C  CD1 . PHE   B 2 115 ? 161.458 141.928 124.010 1.00 86.54  ? 177  PHE   R CD1 1 
ATOM   1542 C  CD2 . PHE   B 2 115 ? 160.190 140.221 122.943 1.00 86.54  ? 177  PHE   R CD2 1 
ATOM   1543 C  CE1 . PHE   B 2 115 ? 161.269 142.757 122.924 1.00 86.54  ? 177  PHE   R CE1 1 
ATOM   1544 C  CE2 . PHE   B 2 115 ? 159.993 141.045 121.852 1.00 86.54  ? 177  PHE   R CE2 1 
ATOM   1545 C  CZ  . PHE   B 2 115 ? 160.534 142.317 121.843 1.00 86.54  ? 177  PHE   R CZ  1 
ATOM   1546 N  N   . HIS   B 2 116 ? 164.449 139.820 124.894 1.00 84.46  ? 178  HIS   R N   1 
ATOM   1547 C  CA  . HIS   B 2 116 ? 165.660 140.246 124.192 1.00 84.46  ? 178  HIS   R CA  1 
ATOM   1548 C  C   . HIS   B 2 116 ? 166.773 139.206 124.247 1.00 84.46  ? 178  HIS   R C   1 
ATOM   1549 O  O   . HIS   B 2 116 ? 167.275 138.785 123.201 1.00 84.46  ? 178  HIS   R O   1 
ATOM   1550 C  CB  . HIS   B 2 116 ? 166.201 141.572 124.739 1.00 84.46  ? 178  HIS   R CB  1 
ATOM   1551 C  CG  . HIS   B 2 116 ? 165.231 142.705 124.672 1.00 84.46  ? 178  HIS   R CG  1 
ATOM   1552 N  ND1 . HIS   B 2 116 ? 165.180 143.585 123.615 1.00 84.46  ? 178  HIS   R ND1 1 
ATOM   1553 C  CD2 . HIS   B 2 116 ? 164.267 143.098 125.538 1.00 84.46  ? 178  HIS   R CD2 1 
ATOM   1554 C  CE1 . HIS   B 2 116 ? 164.218 144.464 123.827 1.00 84.46  ? 178  HIS   R CE1 1 
ATOM   1555 N  NE2 . HIS   B 2 116 ? 163.656 144.199 124.992 1.00 84.46  ? 178  HIS   R NE2 1 
ATOM   1556 N  N   . VAL   B 2 117 ? 167.194 138.816 125.452 1.00 82.14  ? 179  VAL   R N   1 
ATOM   1557 C  CA  . VAL   B 2 117 ? 168.285 137.854 125.585 1.00 82.14  ? 179  VAL   R CA  1 
ATOM   1558 C  C   . VAL   B 2 117 ? 167.862 136.497 125.038 1.00 82.14  ? 179  VAL   R C   1 
ATOM   1559 O  O   . VAL   B 2 117 ? 168.579 135.875 124.246 1.00 82.14  ? 179  VAL   R O   1 
ATOM   1560 C  CB  . VAL   B 2 117 ? 168.742 137.765 127.052 1.00 82.14  ? 179  VAL   R CB  1 
ATOM   1561 C  CG1 . VAL   B 2 117 ? 169.585 136.518 127.284 1.00 82.14  ? 179  VAL   R CG1 1 
ATOM   1562 C  CG2 . VAL   B 2 117 ? 169.519 139.013 127.431 1.00 82.14  ? 179  VAL   R CG2 1 
ATOM   1563 N  N   . PHE   B 2 118 ? 166.684 136.034 125.426 1.00 81.97  ? 180  PHE   R N   1 
ATOM   1564 C  CA  . PHE   B 2 118 ? 166.051 134.911 124.760 1.00 81.97  ? 180  PHE   R CA  1 
ATOM   1565 C  C   . PHE   B 2 118 ? 165.040 135.467 123.767 1.00 81.97  ? 180  PHE   R C   1 
ATOM   1566 O  O   . PHE   B 2 118 ? 164.951 136.676 123.545 1.00 81.97  ? 180  PHE   R O   1 
ATOM   1567 C  CB  . PHE   B 2 118 ? 165.374 133.958 125.753 1.00 81.97  ? 180  PHE   R CB  1 
ATOM   1568 C  CG  . PHE   B 2 118 ? 166.292 133.371 126.808 1.00 81.97  ? 180  PHE   R CG  1 
ATOM   1569 C  CD1 . PHE   B 2 118 ? 165.747 132.685 127.881 1.00 81.97  ? 180  PHE   R CD1 1 
ATOM   1570 C  CD2 . PHE   B 2 118 ? 167.676 133.443 126.708 1.00 81.97  ? 180  PHE   R CD2 1 
ATOM   1571 C  CE1 . PHE   B 2 118 ? 166.554 132.128 128.854 1.00 81.97  ? 180  PHE   R CE1 1 
ATOM   1572 C  CE2 . PHE   B 2 118 ? 168.488 132.893 127.680 1.00 81.97  ? 180  PHE   R CE2 1 
ATOM   1573 C  CZ  . PHE   B 2 118 ? 167.926 132.229 128.752 1.00 81.97  ? 180  PHE   R CZ  1 
ATOM   1574 N  N   . HIS   B 2 119 ? 164.274 134.577 123.152 1.00 85.76  ? 181  HIS   R N   1 
ATOM   1575 C  CA  . HIS   B 2 119 ? 163.134 134.992 122.345 1.00 85.76  ? 181  HIS   R CA  1 
ATOM   1576 C  C   . HIS   B 2 119 ? 161.966 134.053 122.588 1.00 85.76  ? 181  HIS   R C   1 
ATOM   1577 O  O   . HIS   B 2 119 ? 161.221 133.703 121.668 1.00 85.76  ? 181  HIS   R O   1 
ATOM   1578 C  CB  . HIS   B 2 119 ? 163.495 135.062 120.863 1.00 85.76  ? 181  HIS   R CB  1 
ATOM   1579 C  CG  . HIS   B 2 119 ? 164.264 136.291 120.491 1.00 85.76  ? 181  HIS   R CG  1 
ATOM   1580 N  ND1 . HIS   B 2 119 ? 165.597 136.458 120.800 1.00 85.76  ? 181  HIS   R ND1 1 
ATOM   1581 C  CD2 . HIS   B 2 119 ? 163.886 137.417 119.841 1.00 85.76  ? 181  HIS   R CD2 1 
ATOM   1582 C  CE1 . HIS   B 2 119 ? 166.007 137.632 120.355 1.00 85.76  ? 181  HIS   R CE1 1 
ATOM   1583 N  NE2 . HIS   B 2 119 ? 164.989 138.234 119.769 1.00 85.76  ? 181  HIS   R NE2 1 
ATOM   1584 N  N   . ARG   B 2 120 ? 161.797 133.637 123.840 1.00 84.12  ? 182  ARG   R N   1 
ATOM   1585 C  CA  . ARG   B 2 120 ? 160.753 132.691 124.205 1.00 84.12  ? 182  ARG   R CA  1 
ATOM   1586 C  C   . ARG   B 2 120 ? 159.400 133.386 124.176 1.00 84.12  ? 182  ARG   R C   1 
ATOM   1587 O  O   . ARG   B 2 120 ? 159.157 134.317 124.951 1.00 84.12  ? 182  ARG   R O   1 
ATOM   1588 C  CB  . ARG   B 2 120 ? 161.029 132.107 125.589 1.00 84.12  ? 182  ARG   R CB  1 
ATOM   1589 N  N   . LYS   B 2 121 ? 158.523 132.942 123.281 1.00 84.23  ? 183  LYS   R N   1 
ATOM   1590 C  CA  . LYS   B 2 121 ? 157.167 133.466 123.252 1.00 84.23  ? 183  LYS   R CA  1 
ATOM   1591 C  C   . LYS   B 2 121 ? 156.372 132.890 124.415 1.00 84.23  ? 183  LYS   R C   1 
ATOM   1592 O  O   . LYS   B 2 121 ? 156.270 131.670 124.567 1.00 84.23  ? 183  LYS   R O   1 
ATOM   1593 C  CB  . LYS   B 2 121 ? 156.491 133.129 121.926 1.00 84.23  ? 183  LYS   R CB  1 
ATOM   1594 C  CG  . LYS   B 2 121 ? 155.002 133.413 121.907 1.00 84.23  ? 183  LYS   R CG  1 
ATOM   1595 C  CD  . LYS   B 2 121 ? 154.435 133.284 120.506 1.00 84.23  ? 183  LYS   R CD  1 
ATOM   1596 C  CE  . LYS   B 2 121 ? 153.353 134.319 120.255 1.00 84.23  ? 183  LYS   R CE  1 
ATOM   1597 N  NZ  . LYS   B 2 121 ? 152.089 133.979 120.961 1.00 84.23  ? 183  LYS   R NZ  1 
ATOM   1598 N  N   . ASP   B 2 122 ? 155.812 133.771 125.238 1.00 86.28  ? 184  ASP   R N   1 
ATOM   1599 C  CA  . ASP   B 2 122 ? 155.097 133.342 126.429 1.00 86.28  ? 184  ASP   R CA  1 
ATOM   1600 C  C   . ASP   B 2 122 ? 153.727 132.787 126.068 1.00 86.28  ? 184  ASP   R C   1 
ATOM   1601 O  O   . ASP   B 2 122 ? 153.051 133.290 125.166 1.00 86.28  ? 184  ASP   R O   1 
ATOM   1602 C  CB  . ASP   B 2 122 ? 154.947 134.506 127.407 1.00 86.28  ? 184  ASP   R CB  1 
ATOM   1603 C  CG  . ASP   B 2 122 ? 154.506 135.782 126.726 1.00 86.28  ? 184  ASP   R CG  1 
ATOM   1604 O  OD1 . ASP   B 2 122 ? 154.495 135.816 125.480 1.00 86.28  ? 184  ASP   R OD1 1 
ATOM   1605 O  OD2 . ASP   B 2 122 ? 154.174 136.754 127.435 1.00 86.28  ? 184  ASP   R OD2 1 
ATOM   1606 N  N   . SER   B 2 123 ? 153.321 131.744 126.784 1.00 83.03  ? 185  SER   R N   1 
ATOM   1607 C  CA  . SER   B 2 123 ? 152.002 131.154 126.611 1.00 83.03  ? 185  SER   R CA  1 
ATOM   1608 C  C   . SER   B 2 123 ? 150.979 131.966 127.402 1.00 83.03  ? 185  SER   R C   1 
ATOM   1609 O  O   . SER   B 2 123 ? 151.264 133.060 127.896 1.00 83.03  ? 185  SER   R O   1 
ATOM   1610 C  CB  . SER   B 2 123 ? 152.019 129.691 127.038 1.00 83.03  ? 185  SER   R CB  1 
ATOM   1611 O  OG  . SER   B 2 123 ? 152.310 129.575 128.419 1.00 83.03  ? 185  SER   R OG  1 
ATOM   1612 N  N   . ARG   B 2 124 ? 149.761 131.439 127.519 1.00 84.63  ? 186  ARG   R N   1 
ATOM   1613 C  CA  . ARG   B 2 124 ? 148.751 132.100 128.336 1.00 84.63  ? 186  ARG   R CA  1 
ATOM   1614 C  C   . ARG   B 2 124 ? 149.110 132.044 129.815 1.00 84.63  ? 186  ARG   R C   1 
ATOM   1615 O  O   . ARG   B 2 124 ? 148.913 133.029 130.537 1.00 84.63  ? 186  ARG   R O   1 
ATOM   1616 C  CB  . ARG   B 2 124 ? 147.384 131.462 128.090 1.00 84.63  ? 186  ARG   R CB  1 
ATOM   1617 C  CG  . ARG   B 2 124 ? 146.275 131.982 128.983 1.00 84.63  ? 186  ARG   R CG  1 
ATOM   1618 C  CD  . ARG   B 2 124 ? 144.903 131.463 128.531 1.00 84.63  ? 186  ARG   R CD  1 
ATOM   1619 N  NE  . ARG   B 2 124 ? 144.690 130.013 128.539 1.00 84.63  ? 186  ARG   R NE  1 
ATOM   1620 C  CZ  . ARG   B 2 124 ? 145.024 129.140 129.488 1.00 84.63  ? 186  ARG   R CZ  1 
ATOM   1621 N  NH1 . ARG   B 2 124 ? 145.392 129.521 130.703 1.00 84.63  ? 186  ARG   R NH1 1 
ATOM   1622 N  NH2 . ARG   B 2 124 ? 144.913 127.840 129.234 1.00 84.63  ? 186  ARG   R NH2 1 
ATOM   1623 N  N   . ASN   B 2 125 ? 149.664 130.915 130.265 1.00 79.29  ? 187  ASN   R N   1 
ATOM   1624 C  CA  . ASN   B 2 125 ? 149.984 130.721 131.676 1.00 79.29  ? 187  ASN   R CA  1 
ATOM   1625 C  C   . ASN   B 2 125 ? 151.046 131.711 132.146 1.00 79.29  ? 187  ASN   R C   1 
ATOM   1626 O  O   . ASN   B 2 125 ? 150.915 132.301 133.224 1.00 79.29  ? 187  ASN   R O   1 
ATOM   1627 C  CB  . ASN   B 2 125 ? 150.440 129.273 131.887 1.00 79.29  ? 187  ASN   R CB  1 
ATOM   1628 C  CG  . ASN   B 2 125 ? 150.596 128.890 133.356 1.00 79.29  ? 187  ASN   R CG  1 
ATOM   1629 O  OD1 . ASN   B 2 125 ? 150.396 129.697 134.261 1.00 79.29  ? 187  ASN   R OD1 1 
ATOM   1630 N  ND2 . ASN   B 2 125 ? 150.955 127.633 133.591 1.00 79.29  ? 187  ASN   R ND2 1 
ATOM   1631 N  N   . VAL   B 2 126 ? 152.091 131.923 131.344 1.00 76.96  ? 188  VAL   R N   1 
ATOM   1632 C  CA  . VAL   B 2 126 ? 153.185 132.797 131.760 1.00 76.96  ? 188  VAL   R CA  1 
ATOM   1633 C  C   . VAL   B 2 126 ? 152.742 134.258 131.769 1.00 76.96  ? 188  VAL   R C   1 
ATOM   1634 O  O   . VAL   B 2 126 ? 153.094 135.021 132.680 1.00 76.96  ? 188  VAL   R O   1 
ATOM   1635 C  CB  . VAL   B 2 126 ? 154.410 132.566 130.858 1.00 76.96  ? 188  VAL   R CB  1 
ATOM   1636 C  CG1 . VAL   B 2 126 ? 155.531 133.531 131.199 1.00 76.96  ? 188  VAL   R CG1 1 
ATOM   1637 C  CG2 . VAL   B 2 126 ? 154.888 131.128 130.990 1.00 76.96  ? 188  VAL   R CG2 1 
ATOM   1638 N  N   . PHE   B 2 127 ? 151.955 134.668 130.769 1.00 76.98  ? 189  PHE   R N   1 
ATOM   1639 C  CA  . PHE   B 2 127 ? 151.408 136.023 130.754 1.00 76.98  ? 189  PHE   R CA  1 
ATOM   1640 C  C   . PHE   B 2 127 ? 150.496 136.259 131.950 1.00 76.98  ? 189  PHE   R C   1 
ATOM   1641 O  O   . PHE   B 2 127 ? 150.547 137.327 132.581 1.00 76.98  ? 189  PHE   R O   1 
ATOM   1642 C  CB  . PHE   B 2 127 ? 150.647 136.262 129.450 1.00 76.98  ? 189  PHE   R CB  1 
ATOM   1643 C  CG  . PHE   B 2 127 ? 150.156 137.672 129.279 1.00 76.98  ? 189  PHE   R CG  1 
ATOM   1644 C  CD1 . PHE   B 2 127 ? 150.988 138.648 128.767 1.00 76.98  ? 189  PHE   R CD1 1 
ATOM   1645 C  CD2 . PHE   B 2 127 ? 148.859 138.019 129.619 1.00 76.98  ? 189  PHE   R CD2 1 
ATOM   1646 C  CE1 . PHE   B 2 127 ? 150.540 139.944 128.601 1.00 76.98  ? 189  PHE   R CE1 1 
ATOM   1647 C  CE2 . PHE   B 2 127 ? 148.410 139.316 129.460 1.00 76.98  ? 189  PHE   R CE2 1 
ATOM   1648 C  CZ  . PHE   B 2 127 ? 149.251 140.277 128.948 1.00 76.98  ? 189  PHE   R CZ  1 
ATOM   1649 N  N   . LEU   B 2 128 ? 149.658 135.269 132.275 1.00 74.20  ? 190  LEU   R N   1 
ATOM   1650 C  CA  . LEU   B 2 128 ? 148.783 135.377 133.436 1.00 74.20  ? 190  LEU   R CA  1 
ATOM   1651 C  C   . LEU   B 2 128 ? 149.587 135.493 134.722 1.00 74.20  ? 190  LEU   R C   1 
ATOM   1652 O  O   . LEU   B 2 128 ? 149.263 136.311 135.590 1.00 74.20  ? 190  LEU   R O   1 
ATOM   1653 C  CB  . LEU   B 2 128 ? 147.850 134.171 133.498 1.00 74.20  ? 190  LEU   R CB  1 
ATOM   1654 C  CG  . LEU   B 2 128 ? 146.636 134.204 132.574 1.00 74.20  ? 190  LEU   R CG  1 
ATOM   1655 C  CD1 . LEU   B 2 128 ? 145.819 132.932 132.703 1.00 74.20  ? 190  LEU   R CD1 1 
ATOM   1656 C  CD2 . LEU   B 2 128 ? 145.793 135.402 132.893 1.00 74.20  ? 190  LEU   R CD2 1 
ATOM   1657 N  N   . PHE   B 2 129 ? 150.654 134.700 134.846 1.00 70.12  ? 191  PHE   R N   1 
ATOM   1658 C  CA  . PHE   B 2 129 ? 151.500 134.754 136.033 1.00 70.12  ? 191  PHE   R CA  1 
ATOM   1659 C  C   . PHE   B 2 129 ? 152.183 136.109 136.175 1.00 70.12  ? 191  PHE   R C   1 
ATOM   1660 O  O   . PHE   B 2 129 ? 152.249 136.664 137.279 1.00 70.12  ? 191  PHE   R O   1 
ATOM   1661 C  CB  . PHE   B 2 129 ? 152.538 133.635 135.977 1.00 70.12  ? 191  PHE   R CB  1 
ATOM   1662 C  CG  . PHE   B 2 129 ? 153.378 133.520 137.213 1.00 70.12  ? 191  PHE   R CG  1 
ATOM   1663 C  CD1 . PHE   B 2 129 ? 152.893 132.877 138.337 1.00 70.12  ? 191  PHE   R CD1 1 
ATOM   1664 C  CD2 . PHE   B 2 129 ? 154.659 134.045 137.248 1.00 70.12  ? 191  PHE   R CD2 1 
ATOM   1665 C  CE1 . PHE   B 2 129 ? 153.667 132.765 139.476 1.00 70.12  ? 191  PHE   R CE1 1 
ATOM   1666 C  CE2 . PHE   B 2 129 ? 155.436 133.939 138.384 1.00 70.12  ? 191  PHE   R CE2 1 
ATOM   1667 C  CZ  . PHE   B 2 129 ? 154.940 133.297 139.498 1.00 70.12  ? 191  PHE   R CZ  1 
ATOM   1668 N  N   . LYS   B 2 130 ? 152.685 136.664 135.068 1.00 72.82  ? 192  LYS   R N   1 
ATOM   1669 C  CA  . LYS   B 2 130 ? 153.385 137.945 135.124 1.00 72.82  ? 192  LYS   R CA  1 
ATOM   1670 C  C   . LYS   B 2 130 ? 152.440 139.082 135.503 1.00 72.82  ? 192  LYS   R C   1 
ATOM   1671 O  O   . LYS   B 2 130 ? 152.753 139.906 136.382 1.00 72.82  ? 192  LYS   R O   1 
ATOM   1672 C  CB  . LYS   B 2 130 ? 154.050 138.226 133.778 1.00 72.82  ? 192  LYS   R CB  1 
ATOM   1673 C  CG  . LYS   B 2 130 ? 155.264 137.360 133.485 1.00 72.82  ? 192  LYS   R CG  1 
ATOM   1674 C  CD  . LYS   B 2 130 ? 155.516 137.266 131.991 1.00 72.82  ? 192  LYS   R CD  1 
ATOM   1675 C  CE  . LYS   B 2 130 ? 156.965 136.927 131.688 1.00 72.82  ? 192  LYS   R CE  1 
ATOM   1676 N  NZ  . LYS   B 2 130 ? 157.144 136.452 130.288 1.00 72.82  ? 192  LYS   R NZ  1 
ATOM   1677 N  N   . LEU   B 2 131 ? 151.274 139.136 134.853 1.00 70.32  ? 193  LEU   R N   1 
ATOM   1678 C  CA  . LEU   B 2 131 ? 150.305 140.178 135.167 1.00 70.32  ? 193  LEU   R CA  1 
ATOM   1679 C  C   . LEU   B 2 131 ? 149.794 140.037 136.595 1.00 70.32  ? 193  LEU   R C   1 
ATOM   1680 O  O   . LEU   B 2 131 ? 149.602 141.043 137.294 1.00 70.32  ? 193  LEU   R O   1 
ATOM   1681 C  CB  . LEU   B 2 131 ? 149.163 140.137 134.151 1.00 70.32  ? 193  LEU   R CB  1 
ATOM   1682 C  CG  . LEU   B 2 131 ? 148.131 141.264 134.099 1.00 70.32  ? 193  LEU   R CG  1 
ATOM   1683 C  CD1 . LEU   B 2 131 ? 147.676 141.423 132.674 1.00 70.32  ? 193  LEU   R CD1 1 
ATOM   1684 C  CD2 . LEU   B 2 131 ? 146.925 140.972 134.974 1.00 70.32  ? 193  LEU   R CD2 1 
ATOM   1685 N  N   . GLY   B 2 132 ? 149.592 138.796 137.052 1.00 67.85  ? 194  GLY   R N   1 
ATOM   1686 C  CA  . GLY   B 2 132 ? 149.198 138.576 138.431 1.00 67.85  ? 194  GLY   R CA  1 
ATOM   1687 C  C   . GLY   B 2 132 ? 150.247 139.034 139.421 1.00 67.85  ? 194  GLY   R C   1 
ATOM   1688 O  O   . GLY   B 2 132 ? 149.917 139.598 140.464 1.00 67.85  ? 194  GLY   R O   1 
ATOM   1689 N  N   . GLY   B 2 133 ? 151.524 138.813 139.103 1.00 65.43  ? 195  GLY   R N   1 
ATOM   1690 C  CA  . GLY   B 2 133 ? 152.585 139.276 139.985 1.00 65.43  ? 195  GLY   R CA  1 
ATOM   1691 C  C   . GLY   B 2 133 ? 152.628 140.787 140.115 1.00 65.43  ? 195  GLY   R C   1 
ATOM   1692 O  O   . GLY   B 2 133 ? 152.765 141.321 141.222 1.00 65.43  ? 195  GLY   R O   1 
ATOM   1693 N  N   . VAL   B 2 134 ? 152.483 141.497 138.994 1.00 65.59  ? 196  VAL   R N   1 
ATOM   1694 C  CA  . VAL   B 2 134 ? 152.517 142.960 139.052 1.00 65.59  ? 196  VAL   R CA  1 
ATOM   1695 C  C   . VAL   B 2 134 ? 151.300 143.510 139.802 1.00 65.59  ? 196  VAL   R C   1 
ATOM   1696 O  O   . VAL   B 2 134 ? 151.424 144.418 140.647 1.00 65.59  ? 196  VAL   R O   1 
ATOM   1697 C  CB  . VAL   B 2 134 ? 152.629 143.544 137.635 1.00 65.59  ? 196  VAL   R CB  1 
ATOM   1698 C  CG1 . VAL   B 2 134 ? 152.616 145.057 137.682 1.00 65.59  ? 196  VAL   R CG1 1 
ATOM   1699 C  CG2 . VAL   B 2 134 ? 153.898 143.051 136.975 1.00 65.59  ? 196  VAL   R CG2 1 
ATOM   1700 N  N   . THR   B 2 135 ? 150.112 142.960 139.524 1.00 62.80  ? 197  THR   R N   1 
ATOM   1701 C  CA  . THR   B 2 135 ? 148.911 143.407 140.225 1.00 62.80  ? 197  THR   R CA  1 
ATOM   1702 C  C   . THR   B 2 135 ? 148.986 143.096 141.717 1.00 62.80  ? 197  THR   R C   1 
ATOM   1703 O  O   . THR   B 2 135 ? 148.524 143.893 142.545 1.00 62.80  ? 197  THR   R O   1 
ATOM   1704 C  CB  . THR   B 2 135 ? 147.672 142.766 139.606 1.00 62.80  ? 197  THR   R CB  1 
ATOM   1705 O  OG1 . THR   B 2 135 ? 147.860 141.351 139.514 1.00 62.80  ? 197  THR   R OG1 1 
ATOM   1706 C  CG2 . THR   B 2 135 ? 147.425 143.328 138.220 1.00 62.80  ? 197  THR   R CG2 1 
ATOM   1707 N  N   . ALA   B 2 136 ? 149.571 141.949 142.076 1.00 63.07  ? 198  ALA   R N   1 
ATOM   1708 C  CA  . ALA   B 2 136 ? 149.759 141.609 143.481 1.00 63.07  ? 198  ALA   R CA  1 
ATOM   1709 C  C   . ALA   B 2 136 ? 150.711 142.577 144.159 1.00 63.07  ? 198  ALA   R C   1 
ATOM   1710 O  O   . ALA   B 2 136 ? 150.505 142.937 145.322 1.00 63.07  ? 198  ALA   R O   1 
ATOM   1711 C  CB  . ALA   B 2 136 ? 150.279 140.180 143.612 1.00 63.07  ? 198  ALA   R CB  1 
ATOM   1712 N  N   . SER   B 2 137 ? 151.755 143.008 143.444 1.00 61.16  ? 199  SER   R N   1 
ATOM   1713 C  CA  . SER   B 2 137 ? 152.678 144.000 143.990 1.00 61.16  ? 199  SER   R CA  1 
ATOM   1714 C  C   . SER   B 2 137 ? 151.962 145.306 144.317 1.00 61.16  ? 199  SER   R C   1 
ATOM   1715 O  O   . SER   B 2 137 ? 152.111 145.854 145.420 1.00 61.16  ? 199  SER   R O   1 
ATOM   1716 C  CB  . SER   B 2 137 ? 153.816 144.249 143.001 1.00 61.16  ? 199  SER   R CB  1 
ATOM   1717 O  OG  . SER   B 2 137 ? 154.620 145.338 143.415 1.00 61.16  ? 199  SER   R OG  1 
ATOM   1718 N  N   . PHE   B 2 138 ? 151.147 145.800 143.380 1.00 61.36  ? 200  PHE   R N   1 
ATOM   1719 C  CA  . PHE   B 2 138 ? 150.437 147.054 143.642 1.00 61.36  ? 200  PHE   R CA  1 
ATOM   1720 C  C   . PHE   B 2 138 ? 149.414 146.912 144.767 1.00 61.36  ? 200  PHE   R C   1 
ATOM   1721 O  O   . PHE   B 2 138 ? 149.306 147.795 145.632 1.00 61.36  ? 200  PHE   R O   1 
ATOM   1722 C  CB  . PHE   B 2 138 ? 149.747 147.565 142.386 1.00 61.36  ? 200  PHE   R CB  1 
ATOM   1723 C  CG  . PHE   B 2 138 ? 149.228 148.963 142.525 1.00 61.36  ? 200  PHE   R CG  1 
ATOM   1724 C  CD1 . PHE   B 2 138 ? 149.951 149.911 143.226 1.00 61.36  ? 200  PHE   R CD1 1 
ATOM   1725 C  CD2 . PHE   B 2 138 ? 148.016 149.329 141.972 1.00 61.36  ? 200  PHE   R CD2 1 
ATOM   1726 C  CE1 . PHE   B 2 138 ? 149.479 151.198 143.363 1.00 61.36  ? 200  PHE   R CE1 1 
ATOM   1727 C  CE2 . PHE   B 2 138 ? 147.543 150.617 142.105 1.00 61.36  ? 200  PHE   R CE2 1 
ATOM   1728 C  CZ  . PHE   B 2 138 ? 148.273 151.550 142.801 1.00 61.36  ? 200  PHE   R CZ  1 
ATOM   1729 N  N   . THR   B 2 139 ? 148.653 145.814 144.770 1.00 58.38  ? 201  THR   R N   1 
ATOM   1730 C  CA  . THR   B 2 139 ? 147.633 145.628 145.795 1.00 58.38  ? 201  THR   R CA  1 
ATOM   1731 C  C   . THR   B 2 139 ? 148.257 145.458 147.176 1.00 58.38  ? 201  THR   R C   1 
ATOM   1732 O  O   . THR   B 2 139 ? 147.713 145.958 148.168 1.00 58.38  ? 201  THR   R O   1 
ATOM   1733 C  CB  . THR   B 2 139 ? 146.754 144.430 145.433 1.00 58.38  ? 201  THR   R CB  1 
ATOM   1734 O  OG1 . THR   B 2 139 ? 146.191 144.638 144.133 1.00 58.38  ? 201  THR   R OG1 1 
ATOM   1735 C  CG2 . THR   B 2 139 ? 145.613 144.273 146.420 1.00 58.38  ? 201  THR   R CG2 1 
ATOM   1736 N  N   . ALA   B 2 140 ? 149.415 144.799 147.256 1.00 54.72  ? 202  ALA   R N   1 
ATOM   1737 C  CA  . ALA   B 2 140 ? 150.105 144.677 148.532 1.00 54.72  ? 202  ALA   R CA  1 
ATOM   1738 C  C   . ALA   B 2 140 ? 150.656 146.016 149.001 1.00 54.72  ? 202  ALA   R C   1 
ATOM   1739 O  O   . ALA   B 2 140 ? 150.684 146.285 150.207 1.00 54.72  ? 202  ALA   R O   1 
ATOM   1740 C  CB  . ALA   B 2 140 ? 151.221 143.648 148.423 1.00 54.72  ? 202  ALA   R CB  1 
ATOM   1741 N  N   . LYS   B 2 141 ? 151.094 146.872 148.068 1.00 54.86  ? 203  LYS   R N   1 
ATOM   1742 C  CA  . LYS   B 2 141 ? 151.496 148.226 148.454 1.00 54.86  ? 203  LYS   R CA  1 
ATOM   1743 C  C   . LYS   B 2 141 ? 150.331 149.001 149.064 1.00 54.86  ? 203  LYS   R C   1 
ATOM   1744 O  O   . LYS   B 2 141 ? 150.473 149.625 150.129 1.00 54.86  ? 203  LYS   R O   1 
ATOM   1745 C  CB  . LYS   B 2 141 ? 152.057 148.973 147.243 1.00 54.86  ? 203  LYS   R CB  1 
ATOM   1746 C  CG  . LYS   B 2 141 ? 153.555 148.815 147.063 1.00 54.86  ? 203  LYS   R CG  1 
ATOM   1747 C  CD  . LYS   B 2 141 ? 154.095 149.635 145.909 1.00 54.86  ? 203  LYS   R CD  1 
ATOM   1748 C  CE  . LYS   B 2 141 ? 154.095 148.847 144.615 1.00 54.86  ? 203  LYS   R CE  1 
ATOM   1749 N  NZ  . LYS   B 2 141 ? 155.026 149.427 143.610 1.00 54.86  ? 203  LYS   R NZ  1 
ATOM   1750 N  N   . VAL   B 2 142 ? 149.161 148.936 148.422 1.00 52.96  ? 204  VAL   R N   1 
ATOM   1751 C  CA  . VAL   B 2 142 ? 147.989 149.654 148.927 1.00 52.96  ? 204  VAL   R CA  1 
ATOM   1752 C  C   . VAL   B 2 142 ? 147.554 149.105 150.284 1.00 52.96  ? 204  VAL   R C   1 
ATOM   1753 O  O   . VAL   B 2 142 ? 147.219 149.865 151.201 1.00 52.96  ? 204  VAL   R O   1 
ATOM   1754 C  CB  . VAL   B 2 142 ? 146.847 149.600 147.897 1.00 52.96  ? 204  VAL   R CB  1 
ATOM   1755 C  CG1 . VAL   B 2 142 ? 145.641 150.357 148.404 1.00 52.96  ? 204  VAL   R CG1 1 
ATOM   1756 C  CG2 . VAL   B 2 142 ? 147.305 150.190 146.585 1.00 52.96  ? 204  VAL   R CG2 1 
ATOM   1757 N  N   . GLY   B 2 143 ? 147.565 147.781 150.441 1.00 51.88  ? 205  GLY   R N   1 
ATOM   1758 C  CA  . GLY   B 2 143 ? 147.194 147.193 151.718 1.00 51.88  ? 205  GLY   R CA  1 
ATOM   1759 C  C   . GLY   B 2 143 ? 148.176 147.477 152.838 1.00 51.88  ? 205  GLY   R C   1 
ATOM   1760 O  O   . GLY   B 2 143 ? 147.775 147.612 154.002 1.00 51.88  ? 205  GLY   R O   1 
ATOM   1761 N  N   . SER   B 2 144 ? 149.471 147.551 152.518 1.00 51.81  ? 206  SER   R N   1 
ATOM   1762 C  CA  . SER   B 2 144 ? 150.449 147.946 153.524 1.00 51.81  ? 206  SER   R CA  1 
ATOM   1763 C  C   . SER   B 2 144 ? 150.210 149.378 153.974 1.00 51.81  ? 206  SER   R C   1 
ATOM   1764 O  O   . SER   B 2 144 ? 150.321 149.686 155.167 1.00 51.81  ? 206  SER   R O   1 
ATOM   1765 C  CB  . SER   B 2 144 ? 151.866 147.787 152.981 1.00 51.81  ? 206  SER   R CB  1 
ATOM   1766 O  OG  . SER   B 2 144 ? 152.149 148.775 152.009 1.00 51.81  ? 206  SER   R OG  1 
ATOM   1767 N  N   . LEU   B 2 145 ? 149.860 150.264 153.036 1.00 49.11  ? 207  LEU   R N   1 
ATOM   1768 C  CA  . LEU   B 2 145 ? 149.484 151.620 153.430 1.00 49.11  ? 207  LEU   R CA  1 
ATOM   1769 C  C   . LEU   B 2 145 ? 148.211 151.632 154.273 1.00 49.11  ? 207  LEU   R C   1 
ATOM   1770 O  O   . LEU   B 2 145 ? 148.079 152.461 155.180 1.00 49.11  ? 207  LEU   R O   1 
ATOM   1771 C  CB  . LEU   B 2 145 ? 149.319 152.502 152.197 1.00 49.11  ? 207  LEU   R CB  1 
ATOM   1772 C  CG  . LEU   B 2 145 ? 150.633 152.897 151.523 1.00 49.11  ? 207  LEU   R CG  1 
ATOM   1773 C  CD1 . LEU   B 2 145 ? 150.371 153.788 150.326 1.00 49.11  ? 207  LEU   R CD1 1 
ATOM   1774 C  CD2 . LEU   B 2 145 ? 151.568 153.575 152.511 1.00 49.11  ? 207  LEU   R CD2 1 
ATOM   1775 N  N   . PHE   B 2 146 ? 147.283 150.710 154.002 1.00 47.97  ? 208  PHE   R N   1 
ATOM   1776 C  CA  . PHE   B 2 146 ? 146.068 150.584 154.810 1.00 47.97  ? 208  PHE   R CA  1 
ATOM   1777 C  C   . PHE   B 2 146 ? 146.391 150.241 156.261 1.00 47.97  ? 208  PHE   R C   1 
ATOM   1778 O  O   . PHE   B 2 146 ? 145.931 150.915 157.199 1.00 47.97  ? 208  PHE   R O   1 
ATOM   1779 C  CB  . PHE   B 2 146 ? 145.154 149.526 154.182 1.00 47.97  ? 208  PHE   R CB  1 
ATOM   1780 C  CG  . PHE   B 2 146 ? 143.838 149.334 154.890 1.00 47.97  ? 208  PHE   R CG  1 
ATOM   1781 C  CD1 . PHE   B 2 146 ? 143.683 148.338 155.838 1.00 47.97  ? 208  PHE   R CD1 1 
ATOM   1782 C  CD2 . PHE   B 2 146 ? 142.747 150.123 154.583 1.00 47.97  ? 208  PHE   R CD2 1 
ATOM   1783 C  CE1 . PHE   B 2 146 ? 142.475 148.153 156.477 1.00 47.97  ? 208  PHE   R CE1 1 
ATOM   1784 C  CE2 . PHE   B 2 146 ? 141.537 149.946 155.221 1.00 47.97  ? 208  PHE   R CE2 1 
ATOM   1785 C  CZ  . PHE   B 2 146 ? 141.402 148.960 156.169 1.00 47.97  ? 208  PHE   R CZ  1 
ATOM   1786 N  N   . LEU   B 2 147 ? 147.192 149.197 156.458 1.00 48.13  ? 209  LEU   R N   1 
ATOM   1787 C  CA  . LEU   B 2 147 ? 147.541 148.789 157.813 1.00 48.13  ? 209  LEU   R CA  1 
ATOM   1788 C  C   . LEU   B 2 147 ? 148.405 149.833 158.511 1.00 48.13  ? 209  LEU   R C   1 
ATOM   1789 O  O   . LEU   B 2 147 ? 148.273 150.033 159.725 1.00 48.13  ? 209  LEU   R O   1 
ATOM   1790 C  CB  . LEU   B 2 147 ? 148.234 147.429 157.784 1.00 48.13  ? 209  LEU   R CB  1 
ATOM   1791 C  CG  . LEU   B 2 147 ? 147.359 146.273 157.294 1.00 48.13  ? 209  LEU   R CG  1 
ATOM   1792 C  CD1 . LEU   B 2 147 ? 147.976 144.958 157.683 1.00 48.13  ? 209  LEU   R CD1 1 
ATOM   1793 C  CD2 . LEU   B 2 147 ? 145.944 146.365 157.840 1.00 48.13  ? 209  LEU   R CD2 1 
ATOM   1794 N  N   . ALA   B 2 148 ? 149.261 150.530 157.758 1.00 46.34  ? 210  ALA   R N   1 
ATOM   1795 C  CA  . ALA   B 2 148 ? 150.052 151.610 158.336 1.00 46.34  ? 210  ALA   R CA  1 
ATOM   1796 C  C   . ALA   B 2 148 ? 149.172 152.765 158.799 1.00 46.34  ? 210  ALA   R C   1 
ATOM   1797 O  O   . ALA   B 2 148 ? 149.426 153.355 159.855 1.00 46.34  ? 210  ALA   R O   1 
ATOM   1798 C  CB  . ALA   B 2 148 ? 151.087 152.092 157.324 1.00 46.34  ? 210  ALA   R CB  1 
ATOM   1799 N  N   . ALA   B 2 149 ? 148.131 153.099 158.028 1.00 45.72  ? 211  ALA   R N   1 
ATOM   1800 C  CA  . ALA   B 2 149 ? 147.211 154.160 158.434 1.00 45.72  ? 211  ALA   R CA  1 
ATOM   1801 C  C   . ALA   B 2 149 ? 146.453 153.790 159.703 1.00 45.72  ? 211  ALA   R C   1 
ATOM   1802 O  O   . ALA   B 2 149 ? 146.277 154.632 160.596 1.00 45.72  ? 211  ALA   R O   1 
ATOM   1803 C  CB  . ALA   B 2 149 ? 146.232 154.465 157.304 1.00 45.72  ? 211  ALA   R CB  1 
ATOM   1804 N  N   . ILE   B 2 150 ? 145.993 152.538 159.795 1.00 43.99  ? 212  ILE   R N   1 
ATOM   1805 C  CA  . ILE   B 2 150 ? 145.290 152.099 161.003 1.00 43.99  ? 212  ILE   R CA  1 
ATOM   1806 C  C   . ILE   B 2 150 ? 146.219 152.145 162.215 1.00 43.99  ? 212  ILE   R C   1 
ATOM   1807 O  O   . ILE   B 2 150 ? 145.836 152.626 163.295 1.00 43.99  ? 212  ILE   R O   1 
ATOM   1808 C  CB  . ILE   B 2 150 ? 144.690 150.697 160.790 1.00 43.99  ? 212  ILE   R CB  1 
ATOM   1809 C  CG1 . ILE   B 2 150 ? 143.420 150.796 159.946 1.00 43.99  ? 212  ILE   R CG1 1 
ATOM   1810 C  CG2 . ILE   B 2 150 ? 144.389 150.019 162.117 1.00 43.99  ? 212  ILE   R CG2 1 
ATOM   1811 C  CD1 . ILE   B 2 150 ? 142.671 149.490 159.805 1.00 43.99  ? 212  ILE   R CD1 1 
ATOM   1812 N  N   . ASP   B 2 151 ? 147.461 151.677 162.045 1.00 45.92  ? 213  ASP   R N   1 
ATOM   1813 C  CA  . ASP   B 2 151 ? 148.434 151.719 163.132 1.00 45.92  ? 213  ASP   R CA  1 
ATOM   1814 C  C   . ASP   B 2 151 ? 148.736 153.149 163.559 1.00 45.92  ? 213  ASP   R C   1 
ATOM   1815 O  O   . ASP   B 2 151 ? 148.886 153.425 164.754 1.00 45.92  ? 213  ASP   R O   1 
ATOM   1816 C  CB  . ASP   B 2 151 ? 149.718 151.010 162.711 1.00 45.92  ? 213  ASP   R CB  1 
ATOM   1817 C  CG  . ASP   B 2 151 ? 150.856 151.239 163.681 1.00 45.92  ? 213  ASP   R CG  1 
ATOM   1818 O  OD1 . ASP   B 2 151 ? 150.835 150.646 164.775 1.00 45.92  ? 213  ASP   R OD1 1 
ATOM   1819 O  OD2 . ASP   B 2 151 ? 151.774 152.014 163.349 1.00 45.92  ? 213  ASP   R OD2 1 
ATOM   1820 N  N   . ARG   B 2 152 ? 148.819 154.073 162.598 1.00 43.55  ? 214  ARG   R N   1 
ATOM   1821 C  CA  . ARG   B 2 152 ? 149.069 155.473 162.928 1.00 43.55  ? 214  ARG   R CA  1 
ATOM   1822 C  C   . ARG   B 2 152 ? 147.918 156.078 163.715 1.00 43.55  ? 214  ARG   R C   1 
ATOM   1823 O  O   . ARG   B 2 152 ? 148.147 156.842 164.662 1.00 43.55  ? 214  ARG   R O   1 
ATOM   1824 C  CB  . ARG   B 2 152 ? 149.320 156.279 161.658 1.00 43.55  ? 214  ARG   R CB  1 
ATOM   1825 C  CG  . ARG   B 2 152 ? 150.738 156.199 161.152 1.00 43.55  ? 214  ARG   R CG  1 
ATOM   1826 C  CD  . ARG   B 2 152 ? 151.725 156.655 162.194 1.00 43.55  ? 214  ARG   R CD  1 
ATOM   1827 N  NE  . ARG   B 2 152 ? 152.384 155.535 162.851 1.00 43.55  ? 214  ARG   R NE  1 
ATOM   1828 C  CZ  . ARG   B 2 152 ? 152.866 155.582 164.084 1.00 43.55  ? 214  ARG   R CZ  1 
ATOM   1829 N  NH1 . ARG   B 2 152 ? 152.810 156.687 164.804 1.00 43.55  ? 214  ARG   R NH1 1 
ATOM   1830 N  NH2 . ARG   B 2 152 ? 153.411 154.492 164.609 1.00 43.55  ? 214  ARG   R NH2 1 
ATOM   1831 N  N   . TYR   B 2 153 ? 146.676 155.757 163.336 1.00 46.25  ? 215  TYR   R N   1 
ATOM   1832 C  CA  . TYR   B 2 153 ? 145.533 156.269 164.088 1.00 46.25  ? 215  TYR   R CA  1 
ATOM   1833 C  C   . TYR   B 2 153 ? 145.535 155.753 165.520 1.00 46.25  ? 215  TYR   R C   1 
ATOM   1834 O  O   . TYR   B 2 153 ? 145.318 156.527 166.462 1.00 46.25  ? 215  TYR   R O   1 
ATOM   1835 C  CB  . TYR   B 2 153 ? 144.218 155.895 163.410 1.00 46.25  ? 215  TYR   R CB  1 
ATOM   1836 C  CG  . TYR   B 2 153 ? 143.019 156.365 164.201 1.00 46.25  ? 215  TYR   R CG  1 
ATOM   1837 C  CD1 . TYR   B 2 153 ? 142.672 157.708 164.232 1.00 46.25  ? 215  TYR   R CD1 1 
ATOM   1838 C  CD2 . TYR   B 2 153 ? 142.252 155.474 164.938 1.00 46.25  ? 215  TYR   R CD2 1 
ATOM   1839 C  CE1 . TYR   B 2 153 ? 141.589 158.148 164.962 1.00 46.25  ? 215  TYR   R CE1 1 
ATOM   1840 C  CE2 . TYR   B 2 153 ? 141.169 155.906 165.673 1.00 46.25  ? 215  TYR   R CE2 1 
ATOM   1841 C  CZ  . TYR   B 2 153 ? 140.842 157.244 165.679 1.00 46.25  ? 215  TYR   R CZ  1 
ATOM   1842 O  OH  . TYR   B 2 153 ? 139.761 157.679 166.407 1.00 46.25  ? 215  TYR   R OH  1 
ATOM   1843 N  N   . ILE   B 2 154 ? 145.790 154.454 165.704 1.00 45.78  ? 216  ILE   R N   1 
ATOM   1844 C  CA  . ILE   B 2 154 ? 145.800 153.894 167.054 1.00 45.78  ? 216  ILE   R CA  1 
ATOM   1845 C  C   . ILE   B 2 154 ? 146.958 154.470 167.865 1.00 45.78  ? 216  ILE   R C   1 
ATOM   1846 O  O   . ILE   B 2 154 ? 146.827 154.716 169.068 1.00 45.78  ? 216  ILE   R O   1 
ATOM   1847 C  CB  . ILE   B 2 154 ? 145.850 152.355 167.005 1.00 45.78  ? 216  ILE   R CB  1 
ATOM   1848 C  CG1 . ILE   B 2 154 ? 144.686 151.801 166.191 1.00 45.78  ? 216  ILE   R CG1 1 
ATOM   1849 C  CG2 . ILE   B 2 154 ? 145.786 151.763 168.401 1.00 45.78  ? 216  ILE   R CG2 1 
ATOM   1850 C  CD1 . ILE   B 2 154 ? 143.342 152.103 166.772 1.00 45.78  ? 216  ILE   R CD1 1 
ATOM   1851 N  N   . SER   B 2 155 ? 148.097 154.720 167.218 1.00 46.07  ? 217  SER   R N   1 
ATOM   1852 C  CA  . SER   B 2 155 ? 149.259 155.228 167.937 1.00 46.07  ? 217  SER   R CA  1 
ATOM   1853 C  C   . SER   B 2 155 ? 149.068 156.671 168.373 1.00 46.07  ? 217  SER   R C   1 
ATOM   1854 O  O   . SER   B 2 155 ? 149.423 157.034 169.499 1.00 46.07  ? 217  SER   R O   1 
ATOM   1855 C  CB  . SER   B 2 155 ? 150.509 155.103 167.070 1.00 46.07  ? 217  SER   R CB  1 
ATOM   1856 O  OG  . SER   B 2 155 ? 151.644 155.605 167.750 1.00 46.07  ? 217  SER   R OG  1 
ATOM   1857 N  N   . ILE   B 2 156 ? 148.521 157.513 167.504 1.00 44.16  ? 218  ILE   R N   1 
ATOM   1858 C  CA  . ILE   B 2 156 ? 148.438 158.935 167.811 1.00 44.16  ? 218  ILE   R CA  1 
ATOM   1859 C  C   . ILE   B 2 156 ? 147.188 159.262 168.614 1.00 44.16  ? 218  ILE   R C   1 
ATOM   1860 O  O   . ILE   B 2 156 ? 147.269 159.887 169.674 1.00 44.16  ? 218  ILE   R O   1 
ATOM   1861 C  CB  . ILE   B 2 156 ? 148.511 159.767 166.515 1.00 44.16  ? 218  ILE   R CB  1 
ATOM   1862 C  CG1 . ILE   B 2 156 ? 149.931 159.759 165.956 1.00 44.16  ? 218  ILE   R CG1 1 
ATOM   1863 C  CG2 . ILE   B 2 156 ? 148.083 161.189 166.778 1.00 44.16  ? 218  ILE   R CG2 1 
ATOM   1864 C  CD1 . ILE   B 2 156 ? 150.007 160.108 164.494 1.00 44.16  ? 218  ILE   R CD1 1 
ATOM   1865 N  N   . HIS   B 2 157 ? 146.011 158.851 168.148 1.00 48.68  ? 219  HIS   R N   1 
ATOM   1866 C  CA  . HIS   B 2 157 ? 144.785 159.342 168.761 1.00 48.68  ? 219  HIS   R CA  1 
ATOM   1867 C  C   . HIS   B 2 157 ? 144.222 158.430 169.841 1.00 48.68  ? 219  HIS   R C   1 
ATOM   1868 O  O   . HIS   B 2 157 ? 143.225 158.793 170.472 1.00 48.68  ? 219  HIS   R O   1 
ATOM   1869 C  CB  . HIS   B 2 157 ? 143.733 159.592 167.685 1.00 48.68  ? 219  HIS   R CB  1 
ATOM   1870 C  CG  . HIS   B 2 157 ? 144.038 160.781 166.834 1.00 48.68  ? 219  HIS   R CG  1 
ATOM   1871 N  ND1 . HIS   B 2 157 ? 144.399 160.678 165.509 1.00 48.68  ? 219  HIS   R ND1 1 
ATOM   1872 C  CD2 . HIS   B 2 157 ? 144.065 162.101 167.130 1.00 48.68  ? 219  HIS   R CD2 1 
ATOM   1873 C  CE1 . HIS   B 2 157 ? 144.621 161.885 165.022 1.00 48.68  ? 219  HIS   R CE1 1 
ATOM   1874 N  NE2 . HIS   B 2 157 ? 144.424 162.766 165.985 1.00 48.68  ? 219  HIS   R NE2 1 
ATOM   1875 N  N   . ARG   B 2 158 ? 144.815 157.262 170.067 1.00 51.14  ? 220  ARG   R N   1 
ATOM   1876 C  CA  . ARG   B 2 158 ? 144.500 156.424 171.223 1.00 51.14  ? 220  ARG   R CA  1 
ATOM   1877 C  C   . ARG   B 2 158 ? 145.800 155.946 171.852 1.00 51.14  ? 220  ARG   R C   1 
ATOM   1878 O  O   . ARG   B 2 158 ? 146.099 154.747 171.842 1.00 51.14  ? 220  ARG   R O   1 
ATOM   1879 C  CB  . ARG   B 2 158 ? 143.622 155.238 170.826 1.00 51.14  ? 220  ARG   R CB  1 
ATOM   1880 C  CG  . ARG   B 2 158 ? 142.254 155.612 170.298 1.00 51.14  ? 220  ARG   R CG  1 
ATOM   1881 C  CD  . ARG   B 2 158 ? 141.239 155.712 171.417 1.00 51.14  ? 220  ARG   R CD  1 
ATOM   1882 N  NE  . ARG   B 2 158 ? 139.921 155.263 170.985 1.00 51.14  ? 220  ARG   R NE  1 
ATOM   1883 C  CZ  . ARG   B 2 158 ? 139.053 156.015 170.323 1.00 51.14  ? 220  ARG   R CZ  1 
ATOM   1884 N  NH1 . ARG   B 2 158 ? 139.320 157.274 170.018 1.00 51.14  ? 220  ARG   R NH1 1 
ATOM   1885 N  NH2 . ARG   B 2 158 ? 137.888 155.491 169.957 1.00 51.14  ? 220  ARG   R NH2 1 
ATOM   1886 N  N   . PRO   B 2 159 ? 146.594 156.859 172.427 1.00 47.27  ? 221  PRO   R N   1 
ATOM   1887 C  CA  . PRO   B 2 159 ? 147.936 156.474 172.889 1.00 47.27  ? 221  PRO   R CA  1 
ATOM   1888 C  C   . PRO   B 2 159 ? 147.927 155.543 174.081 1.00 47.27  ? 221  PRO   R C   1 
ATOM   1889 O  O   . PRO   B 2 159 ? 148.910 154.823 174.290 1.00 47.27  ? 221  PRO   R O   1 
ATOM   1890 C  CB  . PRO   B 2 159 ? 148.589 157.816 173.248 1.00 47.27  ? 221  PRO   R CB  1 
ATOM   1891 C  CG  . PRO   B 2 159 ? 147.628 158.873 172.807 1.00 47.27  ? 221  PRO   R CG  1 
ATOM   1892 C  CD  . PRO   B 2 159 ? 146.284 158.245 172.799 1.00 47.27  ? 221  PRO   R CD  1 
ATOM   1893 N  N   . LEU   B 2 160 ? 146.855 155.538 174.871 1.00 57.83  ? 222  LEU   R N   1 
ATOM   1894 C  CA  . LEU   B 2 160 ? 146.784 154.641 176.016 1.00 57.83  ? 222  LEU   R CA  1 
ATOM   1895 C  C   . LEU   B 2 160 ? 146.505 153.209 175.589 1.00 57.83  ? 222  LEU   R C   1 
ATOM   1896 O  O   . LEU   B 2 160 ? 146.963 152.267 176.243 1.00 57.83  ? 222  LEU   R O   1 
ATOM   1897 C  CB  . LEU   B 2 160 ? 145.713 155.130 176.986 1.00 57.83  ? 222  LEU   R CB  1 
ATOM   1898 C  CG  . LEU   B 2 160 ? 145.846 156.608 177.343 1.00 57.83  ? 222  LEU   R CG  1 
ATOM   1899 C  CD1 . LEU   B 2 160 ? 144.608 157.120 178.044 1.00 57.83  ? 222  LEU   R CD1 1 
ATOM   1900 C  CD2 . LEU   B 2 160 ? 147.067 156.798 178.211 1.00 57.83  ? 222  LEU   R CD2 1 
ATOM   1901 N  N   . ALA   B 2 161 ? 145.767 153.027 174.500 1.00 56.64  ? 223  ALA   R N   1 
ATOM   1902 C  CA  . ALA   B 2 161 ? 145.403 151.708 174.010 1.00 56.64  ? 223  ALA   R CA  1 
ATOM   1903 C  C   . ALA   B 2 161 ? 146.371 151.165 172.973 1.00 56.64  ? 223  ALA   R C   1 
ATOM   1904 O  O   . ALA   B 2 161 ? 146.203 150.022 172.538 1.00 56.64  ? 223  ALA   R O   1 
ATOM   1905 C  CB  . ALA   B 2 161 ? 143.997 151.744 173.413 1.00 56.64  ? 223  ALA   R CB  1 
ATOM   1906 N  N   . TYR   B 2 162 ? 147.376 151.947 172.571 1.00 55.41  ? 224  TYR   R N   1 
ATOM   1907 C  CA  . TYR   B 2 162 ? 148.220 151.540 171.452 1.00 55.41  ? 224  TYR   R CA  1 
ATOM   1908 C  C   . TYR   B 2 162 ? 149.131 150.383 171.826 1.00 55.41  ? 224  TYR   R C   1 
ATOM   1909 O  O   . TYR   B 2 162 ? 149.254 149.416 171.067 1.00 55.41  ? 224  TYR   R O   1 
ATOM   1910 C  CB  . TYR   B 2 162 ? 149.054 152.718 170.957 1.00 55.41  ? 224  TYR   R CB  1 
ATOM   1911 C  CG  . TYR   B 2 162 ? 150.165 152.307 170.018 1.00 55.41  ? 224  TYR   R CG  1 
ATOM   1912 C  CD1 . TYR   B 2 162 ? 149.879 151.798 168.758 1.00 55.41  ? 224  TYR   R CD1 1 
ATOM   1913 C  CD2 . TYR   B 2 162 ? 151.497 152.424 170.390 1.00 55.41  ? 224  TYR   R CD2 1 
ATOM   1914 C  CE1 . TYR   B 2 162 ? 150.885 151.423 167.894 1.00 55.41  ? 224  TYR   R CE1 1 
ATOM   1915 C  CE2 . TYR   B 2 162 ? 152.511 152.049 169.530 1.00 55.41  ? 224  TYR   R CE2 1 
ATOM   1916 C  CZ  . TYR   B 2 162 ? 152.197 151.548 168.284 1.00 55.41  ? 224  TYR   R CZ  1 
ATOM   1917 O  OH  . TYR   B 2 162 ? 153.199 151.172 167.422 1.00 55.41  ? 224  TYR   R OH  1 
ATOM   1918 N  N   . LYS   B 2 163 ? 149.775 150.456 172.988 1.00 63.90  ? 225  LYS   R N   1 
ATOM   1919 C  CA  . LYS   B 2 163 ? 150.749 149.441 173.361 1.00 63.90  ? 225  LYS   R CA  1 
ATOM   1920 C  C   . LYS   B 2 163 ? 150.105 148.126 173.779 1.00 63.90  ? 225  LYS   R C   1 
ATOM   1921 O  O   . LYS   B 2 163 ? 150.819 147.132 173.950 1.00 63.90  ? 225  LYS   R O   1 
ATOM   1922 C  CB  . LYS   B 2 163 ? 151.650 149.970 174.477 1.00 63.90  ? 225  LYS   R CB  1 
ATOM   1923 C  CG  . LYS   B 2 163 ? 153.087 149.500 174.361 1.00 63.90  ? 225  LYS   R CG  1 
ATOM   1924 C  CD  . LYS   B 2 163 ? 153.990 150.203 175.357 1.00 63.90  ? 225  LYS   R CD  1 
ATOM   1925 C  CE  . LYS   B 2 163 ? 154.392 151.581 174.860 1.00 63.90  ? 225  LYS   R CE  1 
ATOM   1926 N  NZ  . LYS   B 2 163 ? 155.483 152.168 175.683 1.00 63.90  ? 225  LYS   R NZ  1 
ATOM   1927 N  N   . ARG   B 2 164 ? 148.782 148.094 173.942 1.00 67.58  ? 226  ARG   R N   1 
ATOM   1928 C  CA  . ARG   B 2 164 ? 148.052 146.868 174.225 1.00 67.58  ? 226  ARG   R CA  1 
ATOM   1929 C  C   . ARG   B 2 164 ? 147.225 146.348 173.060 1.00 67.58  ? 226  ARG   R C   1 
ATOM   1930 O  O   . ARG   B 2 164 ? 146.960 145.144 173.012 1.00 67.58  ? 226  ARG   R O   1 
ATOM   1931 C  CB  . ARG   B 2 164 ? 147.119 147.063 175.427 1.00 67.58  ? 226  ARG   R CB  1 
ATOM   1932 C  CG  . ARG   B 2 164 ? 147.758 147.525 176.738 1.00 67.58  ? 226  ARG   R CG  1 
ATOM   1933 C  CD  . ARG   B 2 164 ? 148.979 146.690 177.128 1.00 67.58  ? 226  ARG   R CD  1 
ATOM   1934 N  NE  . ARG   B 2 164 ? 150.264 147.307 176.829 1.00 67.58  ? 226  ARG   R NE  1 
ATOM   1935 C  CZ  . ARG   B 2 164 ? 151.429 146.831 177.250 1.00 67.58  ? 226  ARG   R CZ  1 
ATOM   1936 N  NH1 . ARG   B 2 164 ? 151.501 145.728 177.978 1.00 67.58  ? 226  ARG   R NH1 1 
ATOM   1937 N  NH2 . ARG   B 2 164 ? 152.548 147.477 176.937 1.00 67.58  ? 226  ARG   R NH2 1 
ATOM   1938 N  N   . ILE   B 2 165 ? 146.804 147.204 172.130 1.00 60.61  ? 227  ILE   R N   1 
ATOM   1939 C  CA  . ILE   B 2 165 ? 146.052 146.735 170.970 1.00 60.61  ? 227  ILE   R CA  1 
ATOM   1940 C  C   . ILE   B 2 165 ? 147.025 146.277 169.895 1.00 60.61  ? 227  ILE   R C   1 
ATOM   1941 O  O   . ILE   B 2 165 ? 146.993 145.119 169.465 1.00 60.61  ? 227  ILE   R O   1 
ATOM   1942 C  CB  . ILE   B 2 165 ? 145.110 147.817 170.414 1.00 60.61  ? 227  ILE   R CB  1 
ATOM   1943 C  CG1 . ILE   B 2 165 ? 143.905 148.010 171.325 1.00 60.61  ? 227  ILE   R CG1 1 
ATOM   1944 C  CG2 . ILE   B 2 165 ? 144.624 147.437 169.018 1.00 60.61  ? 227  ILE   R CG2 1 
ATOM   1945 C  CD1 . ILE   B 2 165 ? 142.891 148.962 170.750 1.00 60.61  ? 227  ILE   R CD1 1 
ATOM   1946 N  N   . VAL   B 2 166 ? 147.892 147.183 169.450 1.00 60.07  ? 228  VAL   R N   1 
ATOM   1947 C  CA  . VAL   B 2 166 ? 148.802 146.903 168.345 1.00 60.07  ? 228  VAL   R CA  1 
ATOM   1948 C  C   . VAL   B 2 166 ? 149.972 146.107 168.912 1.00 60.07  ? 228  VAL   R C   1 
ATOM   1949 O  O   . VAL   B 2 166 ? 150.928 146.670 169.447 1.00 60.07  ? 228  VAL   R O   1 
ATOM   1950 C  CB  . VAL   B 2 166 ? 149.269 148.182 167.649 1.00 60.07  ? 228  VAL   R CB  1 
ATOM   1951 C  CG1 . VAL   B 2 166 ? 150.117 147.847 166.438 1.00 60.07  ? 228  VAL   R CG1 1 
ATOM   1952 C  CG2 . VAL   B 2 166 ? 148.073 149.014 167.239 1.00 60.07  ? 228  VAL   R CG2 1 
ATOM   1953 N  N   . THR   B 2 167 ? 149.889 144.788 168.804 1.00 67.00  ? 229  THR   R N   1 
ATOM   1954 C  CA  . THR   B 2 167 ? 150.970 143.896 169.182 1.00 67.00  ? 229  THR   R CA  1 
ATOM   1955 C  C   . THR   B 2 167 ? 151.657 143.371 167.930 1.00 67.00  ? 229  THR   R C   1 
ATOM   1956 O  O   . THR   B 2 167 ? 151.137 143.476 166.817 1.00 67.00  ? 229  THR   R O   1 
ATOM   1957 C  CB  . THR   B 2 167 ? 150.456 142.728 170.031 1.00 67.00  ? 229  THR   R CB  1 
ATOM   1958 O  OG1 . THR   B 2 167 ? 149.435 142.023 169.314 1.00 67.00  ? 229  THR   R OG1 1 
ATOM   1959 C  CG2 . THR   B 2 167 ? 149.887 143.234 171.343 1.00 67.00  ? 229  THR   R CG2 1 
ATOM   1960 N  N   . ARG   B 2 168 ? 152.852 142.821 168.131 1.00 74.18  ? 230  ARG   R N   1 
ATOM   1961 C  CA  . ARG   B 2 168 ? 153.586 142.205 167.027 1.00 74.18  ? 230  ARG   R CA  1 
ATOM   1962 C  C   . ARG   B 2 168 ? 152.870 141.007 166.401 1.00 74.18  ? 230  ARG   R C   1 
ATOM   1963 O  O   . ARG   B 2 168 ? 152.801 140.956 165.158 1.00 74.18  ? 230  ARG   R O   1 
ATOM   1964 C  CB  . ARG   B 2 168 ? 154.998 141.845 167.503 1.00 74.18  ? 230  ARG   R CB  1 
ATOM   1965 C  CG  . ARG   B 2 168 ? 155.984 141.518 166.397 1.00 74.18  ? 230  ARG   R CG  1 
ATOM   1966 C  CD  . ARG   B 2 168 ? 157.466 141.371 166.837 1.00 74.18  ? 230  ARG   R CD  1 
ATOM   1967 N  NE  . ARG   B 2 168 ? 158.018 142.446 167.663 1.00 74.18  ? 230  ARG   R NE  1 
ATOM   1968 C  CZ  . ARG   B 2 168 ? 157.913 142.548 168.984 1.00 74.18  ? 230  ARG   R CZ  1 
ATOM   1969 N  NH1 . ARG   B 2 168 ? 157.378 141.583 169.715 1.00 74.18  ? 230  ARG   R NH1 1 
ATOM   1970 N  NH2 . ARG   B 2 168 ? 158.385 143.634 169.590 1.00 74.18  ? 230  ARG   R NH2 1 
ATOM   1971 N  N   . PRO   B 2 169 ? 152.340 140.016 167.153 1.00 71.25  ? 231  PRO   R N   1 
ATOM   1972 C  CA  . PRO   B 2 169 ? 151.627 138.920 166.469 1.00 71.25  ? 231  PRO   R CA  1 
ATOM   1973 C  C   . PRO   B 2 169 ? 150.383 139.364 165.723 1.00 71.25  ? 231  PRO   R C   1 
ATOM   1974 O  O   . PRO   B 2 169 ? 150.109 138.845 164.634 1.00 71.25  ? 231  PRO   R O   1 
ATOM   1975 C  CB  . PRO   B 2 169 ? 151.281 137.957 167.614 1.00 71.25  ? 231  PRO   R CB  1 
ATOM   1976 C  CG  . PRO   B 2 169 ? 152.248 138.270 168.674 1.00 71.25  ? 231  PRO   R CG  1 
ATOM   1977 C  CD  . PRO   B 2 169 ? 152.404 139.742 168.604 1.00 71.25  ? 231  PRO   R CD  1 
ATOM   1978 N  N   . LYS   B 2 170 ? 149.634 140.327 166.265 1.00 64.33  ? 232  LYS   R N   1 
ATOM   1979 C  CA  . LYS   B 2 170 ? 148.436 140.805 165.583 1.00 64.33  ? 232  LYS   R CA  1 
ATOM   1980 C  C   . LYS   B 2 170 ? 148.787 141.528 164.289 1.00 64.33  ? 232  LYS   R C   1 
ATOM   1981 O  O   . LYS   B 2 170 ? 148.123 141.335 163.263 1.00 64.33  ? 232  LYS   R O   1 
ATOM   1982 C  CB  . LYS   B 2 170 ? 147.637 141.716 166.511 1.00 64.33  ? 232  LYS   R CB  1 
ATOM   1983 C  CG  . LYS   B 2 170 ? 146.136 141.612 166.338 1.00 64.33  ? 232  LYS   R CG  1 
ATOM   1984 C  CD  . LYS   B 2 170 ? 145.410 142.426 167.394 1.00 64.33  ? 232  LYS   R CD  1 
ATOM   1985 C  CE  . LYS   B 2 170 ? 145.583 141.813 168.771 1.00 64.33  ? 232  LYS   R CE  1 
ATOM   1986 N  NZ  . LYS   B 2 170 ? 144.836 142.568 169.812 1.00 64.33  ? 232  LYS   R NZ  1 
ATOM   1987 N  N   . ALA   B 2 171 ? 149.839 142.349 164.317 1.00 65.20  ? 233  ALA   R N   1 
ATOM   1988 C  CA  . ALA   B 2 171 ? 150.281 143.041 163.111 1.00 65.20  ? 233  ALA   R CA  1 
ATOM   1989 C  C   . ALA   B 2 171 ? 150.795 142.062 162.064 1.00 65.20  ? 233  ALA   R C   1 
ATOM   1990 O  O   . ALA   B 2 171 ? 150.505 142.216 160.871 1.00 65.20  ? 233  ALA   R O   1 
ATOM   1991 C  CB  . ALA   B 2 171 ? 151.357 144.066 163.463 1.00 65.20  ? 233  ALA   R CB  1 
ATOM   1992 N  N   . VAL   B 2 172 ? 151.553 141.049 162.492 1.00 66.65  ? 234  VAL   R N   1 
ATOM   1993 C  CA  . VAL   B 2 172 ? 152.070 140.049 161.561 1.00 66.65  ? 234  VAL   R CA  1 
ATOM   1994 C  C   . VAL   B 2 172 ? 150.925 139.271 160.922 1.00 66.65  ? 234  VAL   R C   1 
ATOM   1995 O  O   . VAL   B 2 172 ? 150.920 139.028 159.707 1.00 66.65  ? 234  VAL   R O   1 
ATOM   1996 C  CB  . VAL   B 2 172 ? 153.067 139.124 162.284 1.00 66.65  ? 234  VAL   R CB  1 
ATOM   1997 C  CG1 . VAL   B 2 172 ? 153.247 137.812 161.537 1.00 66.65  ? 234  VAL   R CG1 1 
ATOM   1998 C  CG2 . VAL   B 2 172 ? 154.404 139.826 162.454 1.00 66.65  ? 234  VAL   R CG2 1 
ATOM   1999 N  N   . VAL   B 2 173 ? 149.920 138.904 161.724 1.00 68.26  ? 235  VAL   R N   1 
ATOM   2000 C  CA  . VAL   B 2 173 ? 148.761 138.182 161.206 1.00 68.26  ? 235  VAL   R CA  1 
ATOM   2001 C  C   . VAL   B 2 173 ? 147.986 139.043 160.213 1.00 68.26  ? 235  VAL   R C   1 
ATOM   2002 O  O   . VAL   B 2 173 ? 147.582 138.566 159.146 1.00 68.26  ? 235  VAL   R O   1 
ATOM   2003 C  CB  . VAL   B 2 173 ? 147.875 137.705 162.375 1.00 68.26  ? 235  VAL   R CB  1 
ATOM   2004 C  CG1 . VAL   B 2 173 ? 146.455 137.407 161.914 1.00 68.26  ? 235  VAL   R CG1 1 
ATOM   2005 C  CG2 . VAL   B 2 173 ? 148.485 136.479 163.027 1.00 68.26  ? 235  VAL   R CG2 1 
ATOM   2006 N  N   . ALA   B 2 174 ? 147.789 140.326 160.534 1.00 64.02  ? 236  ALA   R N   1 
ATOM   2007 C  CA  . ALA   B 2 174 ? 147.053 141.212 159.634 1.00 64.02  ? 236  ALA   R CA  1 
ATOM   2008 C  C   . ALA   B 2 174 ? 147.796 141.422 158.319 1.00 64.02  ? 236  ALA   R C   1 
ATOM   2009 O  O   . ALA   B 2 174 ? 147.180 141.443 157.244 1.00 64.02  ? 236  ALA   R O   1 
ATOM   2010 C  CB  . ALA   B 2 174 ? 146.786 142.550 160.319 1.00 64.02  ? 236  ALA   R CB  1 
ATOM   2011 N  N   . PHE   B 2 175 ? 149.123 141.565 158.382 1.00 62.70  ? 237  PHE   R N   1 
ATOM   2012 C  CA  . PHE   B 2 175 ? 149.909 141.722 157.163 1.00 62.70  ? 237  PHE   R CA  1 
ATOM   2013 C  C   . PHE   B 2 175 ? 149.882 140.457 156.317 1.00 62.70  ? 237  PHE   R C   1 
ATOM   2014 O  O   . PHE   B 2 175 ? 149.804 140.530 155.085 1.00 62.70  ? 237  PHE   R O   1 
ATOM   2015 C  CB  . PHE   B 2 175 ? 151.345 142.109 157.510 1.00 62.70  ? 237  PHE   R CB  1 
ATOM   2016 C  CG  . PHE   B 2 175 ? 151.549 143.586 157.649 1.00 62.70  ? 237  PHE   R CG  1 
ATOM   2017 C  CD1 . PHE   B 2 175 ? 151.321 144.431 156.578 1.00 62.70  ? 237  PHE   R CD1 1 
ATOM   2018 C  CD2 . PHE   B 2 175 ? 151.962 144.131 158.853 1.00 62.70  ? 237  PHE   R CD2 1 
ATOM   2019 C  CE1 . PHE   B 2 175 ? 151.499 145.792 156.707 1.00 62.70  ? 237  PHE   R CE1 1 
ATOM   2020 C  CE2 . PHE   B 2 175 ? 152.144 145.491 158.987 1.00 62.70  ? 237  PHE   R CE2 1 
ATOM   2021 C  CZ  . PHE   B 2 175 ? 151.911 146.320 157.914 1.00 62.70  ? 237  PHE   R CZ  1 
ATOM   2022 N  N   . CYS   B 2 176 ? 149.937 139.288 156.961 1.00 64.60  ? 238  CYS   R N   1 
ATOM   2023 C  CA  . CYS   B 2 176 ? 149.850 138.032 156.225 1.00 64.60  ? 238  CYS   R CA  1 
ATOM   2024 C  C   . CYS   B 2 176 ? 148.487 137.865 155.565 1.00 64.60  ? 238  CYS   R C   1 
ATOM   2025 O  O   . CYS   B 2 176 ? 148.402 137.400 154.424 1.00 64.60  ? 238  CYS   R O   1 
ATOM   2026 C  CB  . CYS   B 2 176 ? 150.147 136.860 157.156 1.00 64.60  ? 238  CYS   R CB  1 
ATOM   2027 S  SG  . CYS   B 2 176 ? 151.888 136.705 157.601 1.00 64.60  ? 238  CYS   R SG  1 
ATOM   2028 N  N   . LEU   B 2 177 ? 147.413 138.240 156.265 1.00 64.86  ? 239  LEU   R N   1 
ATOM   2029 C  CA  . LEU   B 2 177 ? 146.078 138.164 155.675 1.00 64.86  ? 239  LEU   R CA  1 
ATOM   2030 C  C   . LEU   B 2 177 ? 145.933 139.108 154.486 1.00 64.86  ? 239  LEU   R C   1 
ATOM   2031 O  O   . LEU   B 2 177 ? 145.339 138.737 153.464 1.00 64.86  ? 239  LEU   R O   1 
ATOM   2032 C  CB  . LEU   B 2 177 ? 145.007 138.451 156.728 1.00 64.86  ? 239  LEU   R CB  1 
ATOM   2033 C  CG  . LEU   B 2 177 ? 144.376 137.272 157.481 1.00 64.86  ? 239  LEU   R CG  1 
ATOM   2034 C  CD1 . LEU   B 2 177 ? 143.567 136.425 156.514 1.00 64.86  ? 239  LEU   R CD1 1 
ATOM   2035 C  CD2 . LEU   B 2 177 ? 145.392 136.404 158.196 1.00 64.86  ? 239  LEU   R CD2 1 
ATOM   2036 N  N   . MET   B 2 178 ? 146.479 140.324 154.595 1.00 64.61  ? 240  MET   R N   1 
ATOM   2037 C  CA  . MET   B 2 178 ? 146.438 141.255 153.470 1.00 64.61  ? 240  MET   R CA  1 
ATOM   2038 C  C   . MET   B 2 178 ? 147.239 140.726 152.284 1.00 64.61  ? 240  MET   R C   1 
ATOM   2039 O  O   . MET   B 2 178 ? 146.792 140.818 151.132 1.00 64.61  ? 240  MET   R O   1 
ATOM   2040 C  CB  . MET   B 2 178 ? 146.938 142.629 153.926 1.00 64.61  ? 240  MET   R CB  1 
ATOM   2041 C  CG  . MET   B 2 178 ? 146.940 143.756 152.887 1.00 64.61  ? 240  MET   R CG  1 
ATOM   2042 S  SD  . MET   B 2 178 ? 148.219 143.770 151.605 1.00 64.61  ? 240  MET   R SD  1 
ATOM   2043 C  CE  . MET   B 2 178 ? 149.695 143.637 152.609 1.00 64.61  ? 240  MET   R CE  1 
ATOM   2044 N  N   . TRP   B 2 179 ? 148.427 140.173 152.544 1.00 62.15  ? 241  TRP   R N   1 
ATOM   2045 C  CA  . TRP   B 2 179 ? 149.242 139.636 151.459 1.00 62.15  ? 241  TRP   R CA  1 
ATOM   2046 C  C   . TRP   B 2 179 ? 148.556 138.456 150.785 1.00 62.15  ? 241  TRP   R C   1 
ATOM   2047 O  O   . TRP   B 2 179 ? 148.585 138.333 149.556 1.00 62.15  ? 241  TRP   R O   1 
ATOM   2048 C  CB  . TRP   B 2 179 ? 150.614 139.226 151.988 1.00 62.15  ? 241  TRP   R CB  1 
ATOM   2049 C  CG  . TRP   B 2 179 ? 151.703 140.203 151.679 1.00 62.15  ? 241  TRP   R CG  1 
ATOM   2050 C  CD1 . TRP   B 2 179 ? 152.308 141.058 152.552 1.00 62.15  ? 241  TRP   R CD1 1 
ATOM   2051 C  CD2 . TRP   B 2 179 ? 152.325 140.421 150.409 1.00 62.15  ? 241  TRP   R CD2 1 
ATOM   2052 N  NE1 . TRP   B 2 179 ? 153.268 141.795 151.905 1.00 62.15  ? 241  TRP   R NE1 1 
ATOM   2053 C  CE2 . TRP   B 2 179 ? 153.297 141.424 150.587 1.00 62.15  ? 241  TRP   R CE2 1 
ATOM   2054 C  CE3 . TRP   B 2 179 ? 152.155 139.866 149.138 1.00 62.15  ? 241  TRP   R CE3 1 
ATOM   2055 C  CZ2 . TRP   B 2 179 ? 154.096 141.879 149.545 1.00 62.15  ? 241  TRP   R CZ2 1 
ATOM   2056 C  CZ3 . TRP   B 2 179 ? 152.948 140.323 148.104 1.00 62.15  ? 241  TRP   R CZ3 1 
ATOM   2057 C  CH2 . TRP   B 2 179 ? 153.907 141.317 148.314 1.00 62.15  ? 241  TRP   R CH2 1 
ATOM   2058 N  N   . THR   B 2 180 ? 147.903 137.596 151.570 1.00 64.74  ? 242  THR   R N   1 
ATOM   2059 C  CA  . THR   B 2 180 ? 147.244 136.433 150.989 1.00 64.74  ? 242  THR   R CA  1 
ATOM   2060 C  C   . THR   B 2 180 ? 146.007 136.827 150.193 1.00 64.74  ? 242  THR   R C   1 
ATOM   2061 O  O   . THR   B 2 180 ? 145.732 136.232 149.144 1.00 64.74  ? 242  THR   R O   1 
ATOM   2062 C  CB  . THR   B 2 180 ? 146.881 135.426 152.077 1.00 64.74  ? 242  THR   R CB  1 
ATOM   2063 O  OG1 . THR   B 2 180 ? 146.260 136.104 153.171 1.00 64.74  ? 242  THR   R OG1 1 
ATOM   2064 C  CG2 . THR   B 2 180 ? 148.126 134.703 152.570 1.00 64.74  ? 242  THR   R CG2 1 
ATOM   2065 N  N   . ILE   B 2 181 ? 145.247 137.824 150.658 1.00 62.65  ? 243  ILE   R N   1 
ATOM   2066 C  CA  . ILE   B 2 181 ? 144.079 138.223 149.876 1.00 62.65  ? 243  ILE   R CA  1 
ATOM   2067 C  C   . ILE   B 2 181 ? 144.510 138.936 148.594 1.00 62.65  ? 243  ILE   R C   1 
ATOM   2068 O  O   . ILE   B 2 181 ? 143.876 138.765 147.541 1.00 62.65  ? 243  ILE   R O   1 
ATOM   2069 C  CB  . ILE   B 2 181 ? 143.088 139.052 150.725 1.00 62.65  ? 243  ILE   R CB  1 
ATOM   2070 C  CG1 . ILE   B 2 181 ? 141.765 139.238 149.981 1.00 62.65  ? 243  ILE   R CG1 1 
ATOM   2071 C  CG2 . ILE   B 2 181 ? 143.636 140.402 151.114 1.00 62.65  ? 243  ILE   R CG2 1 
ATOM   2072 C  CD1 . ILE   B 2 181 ? 140.647 139.762 150.854 1.00 62.65  ? 243  ILE   R CD1 1 
ATOM   2073 N  N   . ALA   B 2 182 ? 145.622 139.683 148.636 1.00 62.70  ? 244  ALA   R N   1 
ATOM   2074 C  CA  . ALA   B 2 182 ? 146.169 140.268 147.414 1.00 62.70  ? 244  ALA   R CA  1 
ATOM   2075 C  C   . ALA   B 2 182 ? 146.640 139.190 146.444 1.00 62.70  ? 244  ALA   R C   1 
ATOM   2076 O  O   . ALA   B 2 182 ? 146.403 139.286 145.232 1.00 62.70  ? 244  ALA   R O   1 
ATOM   2077 C  CB  . ALA   B 2 182 ? 147.315 141.216 147.758 1.00 62.70  ? 244  ALA   R CB  1 
ATOM   2078 N  N   . ILE   B 2 183 ? 147.287 138.144 146.965 1.00 63.01  ? 245  ILE   R N   1 
ATOM   2079 C  CA  . ILE   B 2 183 ? 147.752 137.041 146.127 1.00 63.01  ? 245  ILE   R CA  1 
ATOM   2080 C  C   . ILE   B 2 183 ? 146.574 136.326 145.474 1.00 63.01  ? 245  ILE   R C   1 
ATOM   2081 O  O   . ILE   B 2 183 ? 146.606 136.020 144.276 1.00 63.01  ? 245  ILE   R O   1 
ATOM   2082 C  CB  . ILE   B 2 183 ? 148.619 136.080 146.964 1.00 63.01  ? 245  ILE   R CB  1 
ATOM   2083 C  CG1 . ILE   B 2 183 ? 150.042 136.622 147.091 1.00 63.01  ? 245  ILE   R CG1 1 
ATOM   2084 C  CG2 . ILE   B 2 183 ? 148.647 134.685 146.364 1.00 63.01  ? 245  ILE   R CG2 1 
ATOM   2085 C  CD1 . ILE   B 2 183 ? 150.862 135.921 148.143 1.00 63.01  ? 245  ILE   R CD1 1 
ATOM   2086 N  N   . VAL   B 2 184 ? 145.510 136.080 146.244 1.00 64.60  ? 246  VAL   R N   1 
ATOM   2087 C  CA  . VAL   B 2 184 ? 144.340 135.370 145.728 1.00 64.60  ? 246  VAL   R CA  1 
ATOM   2088 C  C   . VAL   B 2 184 ? 143.650 136.182 144.635 1.00 64.60  ? 246  VAL   R C   1 
ATOM   2089 O  O   . VAL   B 2 184 ? 143.315 135.654 143.561 1.00 64.60  ? 246  VAL   R O   1 
ATOM   2090 C  CB  . VAL   B 2 184 ? 143.376 135.036 146.883 1.00 64.60  ? 246  VAL   R CB  1 
ATOM   2091 C  CG1 . VAL   B 2 184 ? 141.972 134.762 146.367 1.00 64.60  ? 246  VAL   R CG1 1 
ATOM   2092 C  CG2 . VAL   B 2 184 ? 143.894 133.851 147.678 1.00 64.60  ? 246  VAL   R CG2 1 
ATOM   2093 N  N   . ILE   B 2 185 ? 143.445 137.482 144.881 1.00 63.86  ? 247  ILE   R N   1 
ATOM   2094 C  CA  . ILE   B 2 185 ? 142.756 138.303 143.890 1.00 63.86  ? 247  ILE   R CA  1 
ATOM   2095 C  C   . ILE   B 2 185 ? 143.643 138.510 142.664 1.00 63.86  ? 247  ILE   R C   1 
ATOM   2096 O  O   . ILE   B 2 185 ? 143.144 138.756 141.560 1.00 63.86  ? 247  ILE   R O   1 
ATOM   2097 C  CB  . ILE   B 2 185 ? 142.298 139.633 144.525 1.00 63.86  ? 247  ILE   R CB  1 
ATOM   2098 C  CG1 . ILE   B 2 185 ? 141.351 140.400 143.608 1.00 63.86  ? 247  ILE   R CG1 1 
ATOM   2099 C  CG2 . ILE   B 2 185 ? 143.467 140.534 144.830 1.00 63.86  ? 247  ILE   R CG2 1 
ATOM   2100 C  CD1 . ILE   B 2 185 ? 140.644 141.524 144.313 1.00 63.86  ? 247  ILE   R CD1 1 
ATOM   2101 N  N   . ALA   B 2 186 ? 144.963 138.369 142.820 1.00 66.36  ? 248  ALA   R N   1 
ATOM   2102 C  CA  . ALA   B 2 186 ? 145.843 138.411 141.659 1.00 66.36  ? 248  ALA   R CA  1 
ATOM   2103 C  C   . ALA   B 2 186 ? 145.768 137.124 140.845 1.00 66.36  ? 248  ALA   R C   1 
ATOM   2104 O  O   . ALA   B 2 186 ? 145.781 137.166 139.610 1.00 66.36  ? 248  ALA   R O   1 
ATOM   2105 C  CB  . ALA   B 2 186 ? 147.276 138.668 142.109 1.00 66.36  ? 248  ALA   R CB  1 
ATOM   2106 N  N   . VAL   B 2 187 ? 145.695 135.968 141.516 1.00 67.64  ? 249  VAL   R N   1 
ATOM   2107 C  CA  . VAL   B 2 187 ? 145.813 134.686 140.825 1.00 67.64  ? 249  VAL   R CA  1 
ATOM   2108 C  C   . VAL   B 2 187 ? 144.451 134.161 140.377 1.00 67.64  ? 249  VAL   R C   1 
ATOM   2109 O  O   . VAL   B 2 187 ? 144.373 133.068 139.800 1.00 67.64  ? 249  VAL   R O   1 
ATOM   2110 C  CB  . VAL   B 2 187 ? 146.546 133.673 141.741 1.00 67.64  ? 249  VAL   R CB  1 
ATOM   2111 C  CG1 . VAL   B 2 187 ? 145.673 133.246 142.918 1.00 67.64  ? 249  VAL   R CG1 1 
ATOM   2112 C  CG2 . VAL   B 2 187 ? 147.185 132.501 140.977 1.00 67.64  ? 249  VAL   R CG2 1 
ATOM   2113 N  N   . LEU   B 2 188 ? 143.375 134.905 140.636 1.00 69.81  ? 250  LEU   R N   1 
ATOM   2114 C  CA  . LEU   B 2 188 ? 142.050 134.523 140.136 1.00 69.81  ? 250  LEU   R CA  1 
ATOM   2115 C  C   . LEU   B 2 188 ? 141.955 134.212 138.635 1.00 69.81  ? 250  LEU   R C   1 
ATOM   2116 O  O   . LEU   B 2 188 ? 141.252 133.247 138.294 1.00 69.81  ? 250  LEU   R O   1 
ATOM   2117 C  CB  . LEU   B 2 188 ? 141.020 135.605 140.496 1.00 69.81  ? 250  LEU   R CB  1 
ATOM   2118 C  CG  . LEU   B 2 188 ? 140.437 135.599 141.905 1.00 69.81  ? 250  LEU   R CG  1 
ATOM   2119 C  CD1 . LEU   B 2 188 ? 139.323 136.626 142.004 1.00 69.81  ? 250  LEU   R CD1 1 
ATOM   2120 C  CD2 . LEU   B 2 188 ? 139.944 134.215 142.281 1.00 69.81  ? 250  LEU   R CD2 1 
ATOM   2121 N  N   . PRO   B 2 189 ? 142.569 134.959 137.700 1.00 75.57  ? 251  PRO   R N   1 
ATOM   2122 C  CA  . PRO   B 2 189 ? 142.488 134.523 136.293 1.00 75.57  ? 251  PRO   R CA  1 
ATOM   2123 C  C   . PRO   B 2 189 ? 143.217 133.224 136.010 1.00 75.57  ? 251  PRO   R C   1 
ATOM   2124 O  O   . PRO   B 2 189 ? 142.862 132.527 135.052 1.00 75.57  ? 251  PRO   R O   1 
ATOM   2125 C  CB  . PRO   B 2 189 ? 143.108 135.692 135.517 1.00 75.57  ? 251  PRO   R CB  1 
ATOM   2126 C  CG  . PRO   B 2 189 ? 142.972 136.838 136.400 1.00 75.57  ? 251  PRO   R CG  1 
ATOM   2127 C  CD  . PRO   B 2 189 ? 143.186 136.296 137.776 1.00 75.57  ? 251  PRO   R CD  1 
ATOM   2128 N  N   . LEU   B 2 190 ? 144.228 132.877 136.807 1.00 74.68  ? 252  LEU   R N   1 
ATOM   2129 C  CA  . LEU   B 2 190 ? 144.906 131.600 136.632 1.00 74.68  ? 252  LEU   R CA  1 
ATOM   2130 C  C   . LEU   B 2 190 ? 144.022 130.421 137.013 1.00 74.68  ? 252  LEU   R C   1 
ATOM   2131 O  O   . LEU   B 2 190 ? 144.280 129.299 136.566 1.00 74.68  ? 252  LEU   R O   1 
ATOM   2132 C  CB  . LEU   B 2 190 ? 146.192 131.573 137.457 1.00 74.68  ? 252  LEU   R CB  1 
ATOM   2133 C  CG  . LEU   B 2 190 ? 147.317 130.686 136.931 1.00 74.68  ? 252  LEU   R CG  1 
ATOM   2134 C  CD1 . LEU   B 2 190 ? 147.655 131.076 135.513 1.00 74.68  ? 252  LEU   R CD1 1 
ATOM   2135 C  CD2 . LEU   B 2 190 ? 148.543 130.792 137.821 1.00 74.68  ? 252  LEU   R CD2 1 
ATOM   2136 N  N   . LEU   B 2 191 ? 142.989 130.650 137.819 1.00 76.71  ? 253  LEU   R N   1 
ATOM   2137 C  CA  . LEU   B 2 191 ? 142.082 129.598 138.252 1.00 76.71  ? 253  LEU   R CA  1 
ATOM   2138 C  C   . LEU   B 2 191 ? 140.894 129.419 137.319 1.00 76.71  ? 253  LEU   R C   1 
ATOM   2139 O  O   . LEU   B 2 191 ? 140.015 128.601 137.611 1.00 76.71  ? 253  LEU   R O   1 
ATOM   2140 C  CB  . LEU   B 2 191 ? 141.579 129.881 139.670 1.00 76.71  ? 253  LEU   R CB  1 
ATOM   2141 C  CG  . LEU   B 2 191 ? 142.287 129.179 140.832 1.00 76.71  ? 253  LEU   R CG  1 
ATOM   2142 C  CD1 . LEU   B 2 191 ? 143.788 129.435 140.828 1.00 76.71  ? 253  LEU   R CD1 1 
ATOM   2143 C  CD2 . LEU   B 2 191 ? 141.673 129.600 142.156 1.00 76.71  ? 253  LEU   R CD2 1 
ATOM   2144 N  N   . GLY   B 2 192 ? 140.839 130.155 136.214 1.00 83.97  ? 254  GLY   R N   1 
ATOM   2145 C  CA  . GLY   B 2 192 ? 139.763 129.973 135.264 1.00 83.97  ? 254  GLY   R CA  1 
ATOM   2146 C  C   . GLY   B 2 192 ? 138.969 131.224 134.960 1.00 83.97  ? 254  GLY   R C   1 
ATOM   2147 O  O   . GLY   B 2 192 ? 137.802 131.139 134.570 1.00 83.97  ? 254  GLY   R O   1 
ATOM   2148 N  N   . TRP   B 2 193 ? 139.582 132.390 135.132 1.00 84.69  ? 255  TRP   R N   1 
ATOM   2149 C  CA  . TRP   B 2 193 ? 138.953 133.662 134.800 1.00 84.69  ? 255  TRP   R CA  1 
ATOM   2150 C  C   . TRP   B 2 193 ? 139.712 134.352 133.671 1.00 84.69  ? 255  TRP   R C   1 
ATOM   2151 O  O   . TRP   B 2 193 ? 139.971 135.555 133.710 1.00 84.69  ? 255  TRP   R O   1 
ATOM   2152 C  CB  . TRP   B 2 193 ? 138.854 134.562 136.030 1.00 84.69  ? 255  TRP   R CB  1 
ATOM   2153 C  CG  . TRP   B 2 193 ? 137.825 135.660 135.933 1.00 84.69  ? 255  TRP   R CG  1 
ATOM   2154 C  CD1 . TRP   B 2 193 ? 137.156 136.070 134.816 1.00 84.69  ? 255  TRP   R CD1 1 
ATOM   2155 C  CD2 . TRP   B 2 193 ? 137.367 136.497 137.001 1.00 84.69  ? 255  TRP   R CD2 1 
ATOM   2156 N  NE1 . TRP   B 2 193 ? 136.308 137.104 135.123 1.00 84.69  ? 255  TRP   R NE1 1 
ATOM   2157 C  CE2 . TRP   B 2 193 ? 136.419 137.386 136.459 1.00 84.69  ? 255  TRP   R CE2 1 
ATOM   2158 C  CE3 . TRP   B 2 193 ? 137.667 136.581 138.363 1.00 84.69  ? 255  TRP   R CE3 1 
ATOM   2159 C  CZ2 . TRP   B 2 193 ? 135.768 138.343 137.231 1.00 84.69  ? 255  TRP   R CZ2 1 
ATOM   2160 C  CZ3 . TRP   B 2 193 ? 137.020 137.532 139.128 1.00 84.69  ? 255  TRP   R CZ3 1 
ATOM   2161 C  CH2 . TRP   B 2 193 ? 136.080 138.400 138.560 1.00 84.69  ? 255  TRP   R CH2 1 
ATOM   2162 N  N   . ASN   B 2 194 ? 140.101 133.585 132.659 1.00 93.00  ? 256  ASN   R N   1 
ATOM   2163 C  CA  . ASN   B 2 194 ? 140.623 134.152 131.427 1.00 93.00  ? 256  ASN   R CA  1 
ATOM   2164 C  C   . ASN   B 2 194 ? 139.496 134.294 130.408 1.00 93.00  ? 256  ASN   R C   1 
ATOM   2165 O  O   . ASN   B 2 194 ? 138.486 133.588 130.464 1.00 93.00  ? 256  ASN   R O   1 
ATOM   2166 C  CB  . ASN   B 2 194 ? 141.764 133.293 130.877 1.00 93.00  ? 256  ASN   R CB  1 
ATOM   2167 C  CG  . ASN   B 2 194 ? 141.395 131.826 130.759 1.00 93.00  ? 256  ASN   R CG  1 
ATOM   2168 O  OD1 . ASN   B 2 194 ? 140.501 131.452 130.002 1.00 93.00  ? 256  ASN   R OD1 1 
ATOM   2169 N  ND2 . ASN   B 2 194 ? 142.084 130.986 131.521 1.00 93.00  ? 256  ASN   R ND2 1 
ATOM   2170 N  N   . CYS   B 2 195 ? 139.677 135.225 129.469 1.00 100.11 ? 257  CYS   R N   1 
ATOM   2171 C  CA  . CYS   B 2 195 ? 138.567 135.632 128.616 1.00 100.11 ? 257  CYS   R CA  1 
ATOM   2172 C  C   . CYS   B 2 195 ? 138.192 134.583 127.578 1.00 100.11 ? 257  CYS   R C   1 
ATOM   2173 O  O   . CYS   B 2 195 ? 137.056 134.595 127.093 1.00 100.11 ? 257  CYS   R O   1 
ATOM   2174 C  CB  . CYS   B 2 195 ? 138.879 136.961 127.923 1.00 100.11 ? 257  CYS   R CB  1 
ATOM   2175 S  SG  . CYS   B 2 195 ? 139.991 136.918 126.493 1.00 100.11 ? 257  CYS   R SG  1 
ATOM   2176 N  N   . GLU   B 2 196 ? 139.103 133.674 127.233 1.00 96.57  ? 258  GLU   R N   1 
ATOM   2177 C  CA  . GLU   B 2 196 ? 138.742 132.597 126.323 1.00 96.57  ? 258  GLU   R CA  1 
ATOM   2178 C  C   . GLU   B 2 196 ? 137.846 131.558 126.982 1.00 96.57  ? 258  GLU   R C   1 
ATOM   2179 O  O   . GLU   B 2 196 ? 137.139 130.832 126.275 1.00 96.57  ? 258  GLU   R O   1 
ATOM   2180 C  CB  . GLU   B 2 196 ? 140.002 131.928 125.763 1.00 96.57  ? 258  GLU   R CB  1 
ATOM   2181 C  CG  . GLU   B 2 196 ? 140.746 131.040 126.746 1.00 96.57  ? 258  GLU   R CG  1 
ATOM   2182 C  CD  . GLU   B 2 196 ? 142.013 130.452 126.158 1.00 96.57  ? 258  GLU   R CD  1 
ATOM   2183 O  OE1 . GLU   B 2 196 ? 142.437 130.909 125.076 1.00 96.57  ? 258  GLU   R OE1 1 
ATOM   2184 O  OE2 . GLU   B 2 196 ? 142.586 129.531 126.776 1.00 96.57  ? 258  GLU   R OE2 1 
ATOM   2185 N  N   . LYS   B 2 197 ? 137.852 131.476 128.315 1.00 94.82  ? 259  LYS   R N   1 
ATOM   2186 C  CA  . LYS   B 2 197 ? 136.990 130.519 129.000 1.00 94.82  ? 259  LYS   R CA  1 
ATOM   2187 C  C   . LYS   B 2 197 ? 135.539 130.975 128.983 1.00 94.82  ? 259  LYS   R C   1 
ATOM   2188 O  O   . LYS   B 2 197 ? 134.632 130.170 128.742 1.00 94.82  ? 259  LYS   R O   1 
ATOM   2189 C  CB  . LYS   B 2 197 ? 137.468 130.316 130.436 1.00 94.82  ? 259  LYS   R CB  1 
ATOM   2190 C  CG  . LYS   B 2 197 ? 136.828 129.137 131.140 1.00 94.82  ? 259  LYS   R CG  1 
ATOM   2191 C  CD  . LYS   B 2 197 ? 137.664 128.685 132.324 1.00 94.82  ? 259  LYS   R CD  1 
ATOM   2192 C  CE  . LYS   B 2 197 ? 139.033 128.205 131.874 1.00 94.82  ? 259  LYS   R CE  1 
ATOM   2193 N  NZ  . LYS   B 2 197 ? 139.766 127.502 132.962 1.00 94.82  ? 259  LYS   R NZ  1 
ATOM   2194 N  N   . LEU   B 2 198 ? 135.300 132.262 129.226 1.00 100.28 ? 260  LEU   R N   1 
ATOM   2195 C  CA  . LEU   B 2 198 ? 133.942 132.781 129.304 1.00 100.28 ? 260  LEU   R CA  1 
ATOM   2196 C  C   . LEU   B 2 198 ? 133.311 132.993 127.935 1.00 100.28 ? 260  LEU   R C   1 
ATOM   2197 O  O   . LEU   B 2 198 ? 132.100 133.238 127.872 1.00 100.28 ? 260  LEU   R O   1 
ATOM   2198 C  CB  . LEU   B 2 198 ? 133.914 134.097 130.090 1.00 100.28 ? 260  LEU   R CB  1 
ATOM   2199 C  CG  . LEU   B 2 198 ? 133.854 134.088 131.626 1.00 100.28 ? 260  LEU   R CG  1 
ATOM   2200 C  CD1 . LEU   B 2 198 ? 132.560 133.447 132.109 1.00 100.28 ? 260  LEU   R CD1 1 
ATOM   2201 C  CD2 . LEU   B 2 198 ? 135.067 133.437 132.291 1.00 100.28 ? 260  LEU   R CD2 1 
ATOM   2202 N  N   . GLN   B 2 199 ? 134.103 132.901 126.859 1.00 103.15 ? 261  GLN   R N   1 
ATOM   2203 C  CA  . GLN   B 2 199 ? 133.639 133.067 125.476 1.00 103.15 ? 261  GLN   R CA  1 
ATOM   2204 C  C   . GLN   B 2 199 ? 132.963 134.420 125.263 1.00 103.15 ? 261  GLN   R C   1 
ATOM   2205 O  O   . GLN   B 2 199 ? 131.958 134.530 124.559 1.00 103.15 ? 261  GLN   R O   1 
ATOM   2206 C  CB  . GLN   B 2 199 ? 132.714 131.921 125.055 1.00 103.15 ? 261  GLN   R CB  1 
ATOM   2207 N  N   . SER   B 2 200 ? 133.521 135.459 125.878 1.00 106.54 ? 262  SER   R N   1 
ATOM   2208 C  CA  . SER   B 2 200 ? 132.993 136.811 125.781 1.00 106.54 ? 262  SER   R CA  1 
ATOM   2209 C  C   . SER   B 2 200 ? 134.103 137.755 125.341 1.00 106.54 ? 262  SER   R C   1 
ATOM   2210 O  O   . SER   B 2 200 ? 135.269 137.369 125.224 1.00 106.54 ? 262  SER   R O   1 
ATOM   2211 C  CB  . SER   B 2 200 ? 132.388 137.271 127.114 1.00 106.54 ? 262  SER   R CB  1 
ATOM   2212 O  OG  . SER   B 2 200 ? 131.251 136.495 127.448 1.00 106.54 ? 262  SER   R OG  1 
ATOM   2213 N  N   . VAL   B 2 201 ? 133.722 139.009 125.088 1.00 103.54 ? 263  VAL   R N   1 
ATOM   2214 C  CA  . VAL   B 2 201 ? 134.681 140.013 124.643 1.00 103.54 ? 263  VAL   R CA  1 
ATOM   2215 C  C   . VAL   B 2 201 ? 135.641 140.346 125.779 1.00 103.54 ? 263  VAL   R C   1 
ATOM   2216 O  O   . VAL   B 2 201 ? 135.259 140.381 126.958 1.00 103.54 ? 263  VAL   R O   1 
ATOM   2217 C  CB  . VAL   B 2 201 ? 133.941 141.258 124.111 1.00 103.54 ? 263  VAL   R CB  1 
ATOM   2218 C  CG1 . VAL   B 2 201 ? 133.134 141.954 125.207 1.00 103.54 ? 263  VAL   R CG1 1 
ATOM   2219 C  CG2 . VAL   B 2 201 ? 134.908 142.233 123.447 1.00 103.54 ? 263  VAL   R CG2 1 
ATOM   2220 N  N   . CYS   B 2 202 ? 136.914 140.525 125.438 1.00 98.78  ? 264  CYS   R N   1 
ATOM   2221 C  CA  . CYS   B 2 202 ? 137.934 140.857 126.417 1.00 98.78  ? 264  CYS   R CA  1 
ATOM   2222 C  C   . CYS   B 2 202 ? 138.855 141.934 125.855 1.00 98.78  ? 264  CYS   R C   1 
ATOM   2223 O  O   . CYS   B 2 202 ? 138.746 142.334 124.692 1.00 98.78  ? 264  CYS   R O   1 
ATOM   2224 C  CB  . CYS   B 2 202 ? 138.705 139.605 126.854 1.00 98.78  ? 264  CYS   R CB  1 
ATOM   2225 S  SG  . CYS   B 2 202 ? 139.674 138.725 125.610 1.00 98.78  ? 264  CYS   R SG  1 
ATOM   2226 N  N   . SER   B 2 203 ? 139.766 142.403 126.705 1.00 96.69  ? 265  SER   R N   1 
ATOM   2227 C  CA  . SER   B 2 203 ? 140.532 143.612 126.450 1.00 96.69  ? 265  SER   R CA  1 
ATOM   2228 C  C   . SER   B 2 203 ? 141.543 143.398 125.326 1.00 96.69  ? 265  SER   R C   1 
ATOM   2229 O  O   . SER   B 2 203 ? 141.945 142.274 125.013 1.00 96.69  ? 265  SER   R O   1 
ATOM   2230 C  CB  . SER   B 2 203 ? 141.250 144.062 127.720 1.00 96.69  ? 265  SER   R CB  1 
ATOM   2231 O  OG  . SER   B 2 203 ? 142.072 143.025 128.226 1.00 96.69  ? 265  SER   R OG  1 
ATOM   2232 N  N   . ASP   B 2 204 ? 141.955 144.507 124.714 1.00 96.36  ? 266  ASP   R N   1 
ATOM   2233 C  CA  . ASP   B 2 204 ? 142.904 144.479 123.610 1.00 96.36  ? 266  ASP   R CA  1 
ATOM   2234 C  C   . ASP   B 2 204 ? 144.328 144.806 124.035 1.00 96.36  ? 266  ASP   R C   1 
ATOM   2235 O  O   . ASP   B 2 204 ? 145.277 144.274 123.453 1.00 96.36  ? 266  ASP   R O   1 
ATOM   2236 C  CB  . ASP   B 2 204 ? 142.464 145.444 122.506 1.00 96.36  ? 266  ASP   R CB  1 
ATOM   2237 C  CG  . ASP   B 2 204 ? 142.430 146.884 122.967 1.00 96.36  ? 266  ASP   R CG  1 
ATOM   2238 O  OD1 . ASP   B 2 204 ? 142.327 147.124 124.189 1.00 96.36  ? 266  ASP   R OD1 1 
ATOM   2239 O  OD2 . ASP   B 2 204 ? 142.508 147.778 122.100 1.00 96.36  ? 266  ASP   R OD2 1 
ATOM   2240 N  N   . ILE   B 2 205 ? 144.508 145.674 125.036 1.00 92.92  ? 267  ILE   R N   1 
ATOM   2241 C  CA  . ILE   B 2 205 ? 145.849 145.920 125.561 1.00 92.92  ? 267  ILE   R CA  1 
ATOM   2242 C  C   . ILE   B 2 205 ? 146.322 144.787 126.452 1.00 92.92  ? 267  ILE   R C   1 
ATOM   2243 O  O   . ILE   B 2 205 ? 147.518 144.706 126.756 1.00 92.92  ? 267  ILE   R O   1 
ATOM   2244 C  CB  . ILE   B 2 205 ? 145.931 147.239 126.352 1.00 92.92  ? 267  ILE   R CB  1 
ATOM   2245 C  CG1 . ILE   B 2 205 ? 145.145 147.138 127.660 1.00 92.92  ? 267  ILE   R CG1 1 
ATOM   2246 C  CG2 . ILE   B 2 205 ? 145.421 148.395 125.510 1.00 92.92  ? 267  ILE   R CG2 1 
ATOM   2247 C  CD1 . ILE   B 2 205 ? 145.290 148.349 128.547 1.00 92.92  ? 267  ILE   R CD1 1 
ATOM   2248 N  N   . PHE   B 2 206 ? 145.415 143.914 126.880 1.00 91.14  ? 268  PHE   R N   1 
ATOM   2249 C  CA  . PHE   B 2 206 ? 145.747 142.747 127.690 1.00 91.14  ? 268  PHE   R CA  1 
ATOM   2250 C  C   . PHE   B 2 206 ? 145.056 141.539 127.076 1.00 91.14  ? 268  PHE   R C   1 
ATOM   2251 O  O   . PHE   B 2 206 ? 143.890 141.254 127.386 1.00 91.14  ? 268  PHE   R O   1 
ATOM   2252 C  CB  . PHE   B 2 206 ? 145.329 142.946 129.143 1.00 91.14  ? 268  PHE   R CB  1 
ATOM   2253 C  CG  . PHE   B 2 206 ? 146.323 143.715 129.957 1.00 91.14  ? 268  PHE   R CG  1 
ATOM   2254 C  CD1 . PHE   B 2 206 ? 147.681 143.543 129.756 1.00 91.14  ? 268  PHE   R CD1 1 
ATOM   2255 C  CD2 . PHE   B 2 206 ? 145.900 144.604 130.929 1.00 91.14  ? 268  PHE   R CD2 1 
ATOM   2256 C  CE1 . PHE   B 2 206 ? 148.598 144.249 130.507 1.00 91.14  ? 268  PHE   R CE1 1 
ATOM   2257 C  CE2 . PHE   B 2 206 ? 146.814 145.312 131.684 1.00 91.14  ? 268  PHE   R CE2 1 
ATOM   2258 C  CZ  . PHE   B 2 206 ? 148.161 145.135 131.472 1.00 91.14  ? 268  PHE   R CZ  1 
ATOM   2259 N  N   . PRO   B 2 207 ? 145.728 140.829 126.169 1.00 89.99  ? 269  PRO   R N   1 
ATOM   2260 C  CA  . PRO   B 2 207 ? 145.179 139.563 125.672 1.00 89.99  ? 269  PRO   R CA  1 
ATOM   2261 C  C   . PRO   B 2 207 ? 145.069 138.537 126.788 1.00 89.99  ? 269  PRO   R C   1 
ATOM   2262 O  O   . PRO   B 2 207 ? 145.879 138.512 127.717 1.00 89.99  ? 269  PRO   R O   1 
ATOM   2263 C  CB  . PRO   B 2 207 ? 146.194 139.127 124.610 1.00 89.99  ? 269  PRO   R CB  1 
ATOM   2264 C  CG  . PRO   B 2 207 ? 146.930 140.372 124.244 1.00 89.99  ? 269  PRO   R CG  1 
ATOM   2265 C  CD  . PRO   B 2 207 ? 146.981 141.191 125.490 1.00 89.99  ? 269  PRO   R CD  1 
ATOM   2266 N  N   . HIS   B 2 208 ? 144.034 137.696 126.683 1.00 91.81  ? 270  HIS   R N   1 
ATOM   2267 C  CA  . HIS   B 2 208 ? 143.694 136.663 127.668 1.00 91.81  ? 270  HIS   R CA  1 
ATOM   2268 C  C   . HIS   B 2 208 ? 143.407 137.249 129.049 1.00 91.81  ? 270  HIS   R C   1 
ATOM   2269 O  O   . HIS   B 2 208 ? 143.634 136.595 130.067 1.00 91.81  ? 270  HIS   R O   1 
ATOM   2270 C  CB  . HIS   B 2 208 ? 144.782 135.586 127.765 1.00 91.81  ? 270  HIS   R CB  1 
ATOM   2271 C  CG  . HIS   B 2 208 ? 145.173 135.001 126.445 1.00 91.81  ? 270  HIS   R CG  1 
ATOM   2272 N  ND1 . HIS   B 2 208 ? 146.229 135.483 125.703 1.00 91.81  ? 270  HIS   R ND1 1 
ATOM   2273 C  CD2 . HIS   B 2 208 ? 144.645 133.980 125.729 1.00 91.81  ? 270  HIS   R CD2 1 
ATOM   2274 C  CE1 . HIS   B 2 208 ? 146.339 134.781 124.590 1.00 91.81  ? 270  HIS   R CE1 1 
ATOM   2275 N  NE2 . HIS   B 2 208 ? 145.390 133.863 124.581 1.00 91.81  ? 270  HIS   R NE2 1 
ATOM   2276 N  N   . ILE   B 2 209 ? 142.898 138.479 129.095 1.00 88.08  ? 271  ILE   R N   1 
ATOM   2277 C  CA  . ILE   B 2 209 ? 142.421 139.108 130.324 1.00 88.08  ? 271  ILE   R CA  1 
ATOM   2278 C  C   . ILE   B 2 209 ? 141.003 139.590 130.073 1.00 88.08  ? 271  ILE   R C   1 
ATOM   2279 O  O   . ILE   B 2 209 ? 140.776 140.407 129.174 1.00 88.08  ? 271  ILE   R O   1 
ATOM   2280 C  CB  . ILE   B 2 209 ? 143.306 140.286 130.767 1.00 88.08  ? 271  ILE   R CB  1 
ATOM   2281 C  CG1 . ILE   B 2 209 ? 144.744 139.843 131.017 1.00 88.08  ? 271  ILE   R CG1 1 
ATOM   2282 C  CG2 . ILE   B 2 209 ? 142.738 140.930 132.018 1.00 88.08  ? 271  ILE   R CG2 1 
ATOM   2283 C  CD1 . ILE   B 2 209 ? 144.873 138.825 132.105 1.00 88.08  ? 271  ILE   R CD1 1 
ATOM   2284 N  N   . ASP   B 2 210 ? 140.059 139.111 130.875 1.00 89.40  ? 272  ASP   R N   1 
ATOM   2285 C  CA  . ASP   B 2 210 ? 138.673 139.507 130.697 1.00 89.40  ? 272  ASP   R CA  1 
ATOM   2286 C  C   . ASP   B 2 210 ? 138.438 140.921 131.219 1.00 89.40  ? 272  ASP   R C   1 
ATOM   2287 O  O   . ASP   B 2 210 ? 139.217 141.467 132.003 1.00 89.40  ? 272  ASP   R O   1 
ATOM   2288 C  CB  . ASP   B 2 210 ? 137.733 138.527 131.395 1.00 89.40  ? 272  ASP   R CB  1 
ATOM   2289 C  CG  . ASP   B 2 210 ? 136.363 138.480 130.748 1.00 89.40  ? 272  ASP   R CG  1 
ATOM   2290 O  OD1 . ASP   B 2 210 ? 135.585 139.437 130.940 1.00 89.40  ? 272  ASP   R OD1 1 
ATOM   2291 O  OD2 . ASP   B 2 210 ? 136.068 137.493 130.042 1.00 89.40  ? 272  ASP   R OD2 1 
ATOM   2292 N  N   . LYS   B 2 211 ? 137.337 141.513 130.759 1.00 86.19  ? 273  LYS   R N   1 
ATOM   2293 C  CA  . LYS   B 2 211 ? 137.021 142.895 131.098 1.00 86.19  ? 273  LYS   R CA  1 
ATOM   2294 C  C   . LYS   B 2 211 ? 136.520 143.013 132.533 1.00 86.19  ? 273  LYS   R C   1 
ATOM   2295 O  O   . LYS   B 2 211 ? 136.885 143.954 133.255 1.00 86.19  ? 273  LYS   R O   1 
ATOM   2296 C  CB  . LYS   B 2 211 ? 135.975 143.414 130.116 1.00 86.19  ? 273  LYS   R CB  1 
ATOM   2297 C  CG  . LYS   B 2 211 ? 135.672 144.885 130.191 1.00 86.19  ? 273  LYS   R CG  1 
ATOM   2298 C  CD  . LYS   B 2 211 ? 136.514 145.629 129.175 1.00 86.19  ? 273  LYS   R CD  1 
ATOM   2299 C  CE  . LYS   B 2 211 ? 136.036 147.052 129.010 1.00 86.19  ? 273  LYS   R CE  1 
ATOM   2300 N  NZ  . LYS   B 2 211 ? 136.229 147.556 127.624 1.00 86.19  ? 273  LYS   R NZ  1 
ATOM   2301 N  N   . THR   B 2 212 ? 135.681 142.062 132.956 1.00 84.89  ? 274  THR   R N   1 
ATOM   2302 C  CA  . THR   B 2 212 ? 135.043 142.130 134.268 1.00 84.89  ? 274  THR   R CA  1 
ATOM   2303 C  C   . THR   B 2 212 ? 136.064 142.034 135.393 1.00 84.89  ? 274  THR   R C   1 
ATOM   2304 O  O   . THR   B 2 212 ? 135.959 142.750 136.398 1.00 84.89  ? 274  THR   R O   1 
ATOM   2305 C  CB  . THR   B 2 212 ? 134.005 141.020 134.401 1.00 84.89  ? 274  THR   R CB  1 
ATOM   2306 O  OG1 . THR   B 2 212 ? 134.675 139.765 134.565 1.00 84.89  ? 274  THR   R OG1 1 
ATOM   2307 C  CG2 . THR   B 2 212 ? 133.130 140.962 133.158 1.00 84.89  ? 274  THR   R CG2 1 
ATOM   2308 N  N   . TYR   B 2 213 ? 137.058 141.154 135.239 1.00 78.77  ? 275  TYR   R N   1 
ATOM   2309 C  CA  . TYR   B 2 213 ? 138.110 141.034 136.242 1.00 78.77  ? 275  TYR   R CA  1 
ATOM   2310 C  C   . TYR   B 2 213 ? 138.884 142.336 136.376 1.00 78.77  ? 275  TYR   R C   1 
ATOM   2311 O  O   . TYR   B 2 213 ? 139.187 142.777 137.492 1.00 78.77  ? 275  TYR   R O   1 
ATOM   2312 C  CB  . TYR   B 2 213 ? 139.058 139.890 135.880 1.00 78.77  ? 275  TYR   R CB  1 
ATOM   2313 C  CG  . TYR   B 2 213 ? 140.347 139.890 136.674 1.00 78.77  ? 275  TYR   R CG  1 
ATOM   2314 C  CD1 . TYR   B 2 213 ? 140.370 139.427 137.981 1.00 78.77  ? 275  TYR   R CD1 1 
ATOM   2315 C  CD2 . TYR   B 2 213 ? 141.536 140.347 136.121 1.00 78.77  ? 275  TYR   R CD2 1 
ATOM   2316 C  CE1 . TYR   B 2 213 ? 141.534 139.419 138.716 1.00 78.77  ? 275  TYR   R CE1 1 
ATOM   2317 C  CE2 . TYR   B 2 213 ? 142.706 140.350 136.854 1.00 78.77  ? 275  TYR   R CE2 1 
ATOM   2318 C  CZ  . TYR   B 2 213 ? 142.698 139.881 138.151 1.00 78.77  ? 275  TYR   R CZ  1 
ATOM   2319 O  OH  . TYR   B 2 213 ? 143.858 139.870 138.888 1.00 78.77  ? 275  TYR   R OH  1 
ATOM   2320 N  N   . LEU   B 2 214 ? 139.201 142.969 135.243 1.00 80.28  ? 276  LEU   R N   1 
ATOM   2321 C  CA  . LEU   B 2 214 ? 139.960 144.213 135.271 1.00 80.28  ? 276  LEU   R CA  1 
ATOM   2322 C  C   . LEU   B 2 214 ? 139.180 145.327 135.954 1.00 80.28  ? 276  LEU   R C   1 
ATOM   2323 O  O   . LEU   B 2 214 ? 139.736 146.049 136.793 1.00 80.28  ? 276  LEU   R O   1 
ATOM   2324 C  CB  . LEU   B 2 214 ? 140.343 144.627 133.853 1.00 80.28  ? 276  LEU   R CB  1 
ATOM   2325 C  CG  . LEU   B 2 214 ? 141.200 145.890 133.778 1.00 80.28  ? 276  LEU   R CG  1 
ATOM   2326 C  CD1 . LEU   B 2 214 ? 142.524 145.658 134.483 1.00 80.28  ? 276  LEU   R CD1 1 
ATOM   2327 C  CD2 . LEU   B 2 214 ? 141.423 146.312 132.339 1.00 80.28  ? 276  LEU   R CD2 1 
ATOM   2328 N  N   . MET   B 2 215 ? 137.889 145.470 135.632 1.00 84.04  ? 277  MET   R N   1 
ATOM   2329 C  CA  . MET   B 2 215 ? 137.133 146.558 136.248 1.00 84.04  ? 277  MET   R CA  1 
ATOM   2330 C  C   . MET   B 2 215 ? 136.904 146.299 137.733 1.00 84.04  ? 277  MET   R C   1 
ATOM   2331 O  O   . MET   B 2 215 ? 136.949 147.236 138.539 1.00 84.04  ? 277  MET   R O   1 
ATOM   2332 C  CB  . MET   B 2 215 ? 135.809 146.804 135.522 1.00 84.04  ? 277  MET   R CB  1 
ATOM   2333 C  CG  . MET   B 2 215 ? 134.930 145.601 135.301 1.00 84.04  ? 277  MET   R CG  1 
ATOM   2334 S  SD  . MET   B 2 215 ? 133.346 146.043 134.559 1.00 84.04  ? 277  MET   R SD  1 
ATOM   2335 C  CE  . MET   B 2 215 ? 132.294 144.730 135.174 1.00 84.04  ? 277  MET   R CE  1 
ATOM   2336 N  N   . PHE   B 2 216 ? 136.709 145.034 138.123 1.00 76.78  ? 278  PHE   R N   1 
ATOM   2337 C  CA  . PHE   B 2 216 ? 136.554 144.717 139.541 1.00 76.78  ? 278  PHE   R CA  1 
ATOM   2338 C  C   . PHE   B 2 216 ? 137.832 145.007 140.323 1.00 76.78  ? 278  PHE   R C   1 
ATOM   2339 O  O   . PHE   B 2 216 ? 137.784 145.603 141.411 1.00 76.78  ? 278  PHE   R O   1 
ATOM   2340 C  CB  . PHE   B 2 216 ? 136.137 143.256 139.694 1.00 76.78  ? 278  PHE   R CB  1 
ATOM   2341 C  CG  . PHE   B 2 216 ? 136.411 142.678 141.050 1.00 76.78  ? 278  PHE   R CG  1 
ATOM   2342 C  CD1 . PHE   B 2 216 ? 135.674 143.077 142.153 1.00 76.78  ? 278  PHE   R CD1 1 
ATOM   2343 C  CD2 . PHE   B 2 216 ? 137.389 141.711 141.217 1.00 76.78  ? 278  PHE   R CD2 1 
ATOM   2344 C  CE1 . PHE   B 2 216 ? 135.920 142.535 143.400 1.00 76.78  ? 278  PHE   R CE1 1 
ATOM   2345 C  CE2 . PHE   B 2 216 ? 137.636 141.166 142.459 1.00 76.78  ? 278  PHE   R CE2 1 
ATOM   2346 C  CZ  . PHE   B 2 216 ? 136.904 141.580 143.552 1.00 76.78  ? 278  PHE   R CZ  1 
ATOM   2347 N  N   . TRP   B 2 217 ? 138.986 144.618 139.769 1.00 71.74  ? 279  TRP   R N   1 
ATOM   2348 C  CA  . TRP   B 2 217 ? 140.259 144.855 140.444 1.00 71.74  ? 279  TRP   R CA  1 
ATOM   2349 C  C   . TRP   B 2 217 ? 140.554 146.345 140.576 1.00 71.74  ? 279  TRP   R C   1 
ATOM   2350 O  O   . TRP   B 2 217 ? 140.961 146.813 141.653 1.00 71.74  ? 279  TRP   R O   1 
ATOM   2351 C  CB  . TRP   B 2 217 ? 141.381 144.149 139.685 1.00 71.74  ? 279  TRP   R CB  1 
ATOM   2352 C  CG  . TRP   B 2 217 ? 142.727 144.342 140.289 1.00 71.74  ? 279  TRP   R CG  1 
ATOM   2353 C  CD1 . TRP   B 2 217 ? 143.252 143.674 141.354 1.00 71.74  ? 279  TRP   R CD1 1 
ATOM   2354 C  CD2 . TRP   B 2 217 ? 143.731 145.267 139.860 1.00 71.74  ? 279  TRP   R CD2 1 
ATOM   2355 N  NE1 . TRP   B 2 217 ? 144.521 144.128 141.617 1.00 71.74  ? 279  TRP   R NE1 1 
ATOM   2356 C  CE2 . TRP   B 2 217 ? 144.837 145.107 140.714 1.00 71.74  ? 279  TRP   R CE2 1 
ATOM   2357 C  CE3 . TRP   B 2 217 ? 143.799 146.218 138.839 1.00 71.74  ? 279  TRP   R CE3 1 
ATOM   2358 C  CZ2 . TRP   B 2 217 ? 145.999 145.862 140.577 1.00 71.74  ? 279  TRP   R CZ2 1 
ATOM   2359 C  CZ3 . TRP   B 2 217 ? 144.953 146.965 138.705 1.00 71.74  ? 279  TRP   R CZ3 1 
ATOM   2360 C  CH2 . TRP   B 2 217 ? 146.036 146.783 139.568 1.00 71.74  ? 279  TRP   R CH2 1 
ATOM   2361 N  N   . ILE   B 2 218 ? 140.335 147.111 139.502 1.00 74.42  ? 280  ILE   R N   1 
ATOM   2362 C  CA  . ILE   B 2 218 ? 140.630 148.538 139.572 1.00 74.42  ? 280  ILE   R CA  1 
ATOM   2363 C  C   . ILE   B 2 218 ? 139.639 149.251 140.487 1.00 74.42  ? 280  ILE   R C   1 
ATOM   2364 O  O   . ILE   B 2 218 ? 140.012 150.208 141.176 1.00 74.42  ? 280  ILE   R O   1 
ATOM   2365 C  CB  . ILE   B 2 218 ? 140.684 149.159 138.160 1.00 74.42  ? 280  ILE   R CB  1 
ATOM   2366 C  CG1 . ILE   B 2 218 ? 141.244 150.574 138.213 1.00 74.42  ? 280  ILE   R CG1 1 
ATOM   2367 C  CG2 . ILE   B 2 218 ? 139.327 149.218 137.501 1.00 74.42  ? 280  ILE   R CG2 1 
ATOM   2368 C  CD1 . ILE   B 2 218 ? 141.611 151.094 136.861 1.00 74.42  ? 280  ILE   R CD1 1 
ATOM   2369 N  N   . GLY   B 2 219 ? 138.390 148.775 140.561 1.00 70.39  ? 281  GLY   R N   1 
ATOM   2370 C  CA  . GLY   B 2 219 ? 137.442 149.367 141.488 1.00 70.39  ? 281  GLY   R CA  1 
ATOM   2371 C  C   . GLY   B 2 219 ? 137.831 149.144 142.936 1.00 70.39  ? 281  GLY   R C   1 
ATOM   2372 O  O   . GLY   B 2 219 ? 137.773 150.072 143.751 1.00 70.39  ? 281  GLY   R O   1 
ATOM   2373 N  N   . VAL   B 2 220 ? 138.262 147.920 143.264 1.00 66.60  ? 282  VAL   R N   1 
ATOM   2374 C  CA  . VAL   B 2 220 ? 138.702 147.615 144.626 1.00 66.60  ? 282  VAL   R CA  1 
ATOM   2375 C  C   . VAL   B 2 220 ? 139.901 148.475 145.009 1.00 66.60  ? 282  VAL   R C   1 
ATOM   2376 O  O   . VAL   B 2 220 ? 139.929 149.095 146.085 1.00 66.60  ? 282  VAL   R O   1 
ATOM   2377 C  CB  . VAL   B 2 220 ? 139.020 146.114 144.756 1.00 66.60  ? 282  VAL   R CB  1 
ATOM   2378 C  CG1 . VAL   B 2 220 ? 139.849 145.840 145.998 1.00 66.60  ? 282  VAL   R CG1 1 
ATOM   2379 C  CG2 . VAL   B 2 220 ? 137.738 145.316 144.799 1.00 66.60  ? 282  VAL   R CG2 1 
ATOM   2380 N  N   . VAL   B 2 221 ? 140.891 148.558 144.113 1.00 64.70  ? 283  VAL   R N   1 
ATOM   2381 C  CA  . VAL   B 2 221 ? 142.113 149.298 144.425 1.00 64.70  ? 283  VAL   R CA  1 
ATOM   2382 C  C   . VAL   B 2 221 ? 141.828 150.793 144.556 1.00 64.70  ? 283  VAL   R C   1 
ATOM   2383 O  O   . VAL   B 2 221 ? 142.335 151.455 145.471 1.00 64.70  ? 283  VAL   R O   1 
ATOM   2384 C  CB  . VAL   B 2 221 ? 143.191 149.001 143.368 1.00 64.70  ? 283  VAL   R CB  1 
ATOM   2385 C  CG1 . VAL   B 2 221 ? 144.369 149.936 143.519 1.00 64.70  ? 283  VAL   R CG1 1 
ATOM   2386 C  CG2 . VAL   B 2 221 ? 143.645 147.561 143.485 1.00 64.70  ? 283  VAL   R CG2 1 
ATOM   2387 N  N   . SER   B 2 222 ? 140.991 151.343 143.668 1.00 65.09  ? 284  SER   R N   1 
ATOM   2388 C  CA  . SER   B 2 222 ? 140.663 152.765 143.727 1.00 65.09  ? 284  SER   R CA  1 
ATOM   2389 C  C   . SER   B 2 222 ? 139.885 153.119 144.991 1.00 65.09  ? 284  SER   R C   1 
ATOM   2390 O  O   . SER   B 2 222 ? 140.141 154.164 145.609 1.00 65.09  ? 284  SER   R O   1 
ATOM   2391 C  CB  . SER   B 2 222 ? 139.870 153.162 142.486 1.00 65.09  ? 284  SER   R CB  1 
ATOM   2392 O  OG  . SER   B 2 222 ? 138.765 152.295 142.298 1.00 65.09  ? 284  SER   R OG  1 
ATOM   2393 N  N   . VAL   B 2 223 ? 138.933 152.265 145.387 1.00 63.20  ? 285  VAL   R N   1 
ATOM   2394 C  CA  . VAL   B 2 223 ? 138.160 152.513 146.603 1.00 63.20  ? 285  VAL   R CA  1 
ATOM   2395 C  C   . VAL   B 2 223 ? 139.072 152.498 147.825 1.00 63.20  ? 285  VAL   R C   1 
ATOM   2396 O  O   . VAL   B 2 223 ? 139.000 153.383 148.693 1.00 63.20  ? 285  VAL   R O   1 
ATOM   2397 C  CB  . VAL   B 2 223 ? 137.019 151.485 146.725 1.00 63.20  ? 285  VAL   R CB  1 
ATOM   2398 C  CG1 . VAL   B 2 223 ? 136.519 151.377 148.158 1.00 63.20  ? 285  VAL   R CG1 1 
ATOM   2399 C  CG2 . VAL   B 2 223 ? 135.880 151.858 145.797 1.00 63.20  ? 285  VAL   R CG2 1 
ATOM   2400 N  N   . LEU   B 2 224 ? 139.974 151.513 147.889 1.00 60.53  ? 286  LEU   R N   1 
ATOM   2401 C  CA  . LEU   B 2 224 ? 140.880 151.430 149.029 1.00 60.53  ? 286  LEU   R CA  1 
ATOM   2402 C  C   . LEU   B 2 224 ? 141.834 152.623 149.063 1.00 60.53  ? 286  LEU   R C   1 
ATOM   2403 O  O   . LEU   B 2 224 ? 142.112 153.174 150.136 1.00 60.53  ? 286  LEU   R O   1 
ATOM   2404 C  CB  . LEU   B 2 224 ? 141.643 150.108 148.984 1.00 60.53  ? 286  LEU   R CB  1 
ATOM   2405 C  CG  . LEU   B 2 224 ? 142.328 149.646 150.266 1.00 60.53  ? 286  LEU   R CG  1 
ATOM   2406 C  CD1 . LEU   B 2 224 ? 141.294 149.508 151.359 1.00 60.53  ? 286  LEU   R CD1 1 
ATOM   2407 C  CD2 . LEU   B 2 224 ? 143.020 148.319 150.041 1.00 60.53  ? 286  LEU   R CD2 1 
ATOM   2408 N  N   . LEU   B 2 225 ? 142.302 153.068 147.892 1.00 59.61  ? 287  LEU   R N   1 
ATOM   2409 C  CA  . LEU   B 2 225 ? 143.215 154.208 147.829 1.00 59.61  ? 287  LEU   R CA  1 
ATOM   2410 C  C   . LEU   B 2 225 ? 142.547 155.500 148.287 1.00 59.61  ? 287  LEU   R C   1 
ATOM   2411 O  O   . LEU   B 2 225 ? 143.149 156.286 149.034 1.00 59.61  ? 287  LEU   R O   1 
ATOM   2412 C  CB  . LEU   B 2 225 ? 143.749 154.366 146.408 1.00 59.61  ? 287  LEU   R CB  1 
ATOM   2413 C  CG  . LEU   B 2 225 ? 145.136 153.792 146.135 1.00 59.61  ? 287  LEU   R CG  1 
ATOM   2414 C  CD1 . LEU   B 2 225 ? 145.550 154.089 144.707 1.00 59.61  ? 287  LEU   R CD1 1 
ATOM   2415 C  CD2 . LEU   B 2 225 ? 146.145 154.357 147.116 1.00 59.61  ? 287  LEU   R CD2 1 
ATOM   2416 N  N   . LEU   B 2 226 ? 141.308 155.745 147.845 1.00 59.91  ? 288  LEU   R N   1 
ATOM   2417 C  CA  . LEU   B 2 226 ? 140.625 156.960 148.282 1.00 59.91  ? 288  LEU   R CA  1 
ATOM   2418 C  C   . LEU   B 2 226 ? 140.318 156.915 149.775 1.00 59.91  ? 288  LEU   R C   1 
ATOM   2419 O  O   . LEU   B 2 226 ? 140.401 157.951 150.458 1.00 59.91  ? 288  LEU   R O   1 
ATOM   2420 C  CB  . LEU   B 2 226 ? 139.359 157.195 147.448 1.00 59.91  ? 288  LEU   R CB  1 
ATOM   2421 C  CG  . LEU   B 2 226 ? 138.165 156.234 147.383 1.00 59.91  ? 288  LEU   R CG  1 
ATOM   2422 C  CD1 . LEU   B 2 226 ? 137.173 156.407 148.535 1.00 59.91  ? 288  LEU   R CD1 1 
ATOM   2423 C  CD2 . LEU   B 2 226 ? 137.453 156.364 146.044 1.00 59.91  ? 288  LEU   R CD2 1 
ATOM   2424 N  N   . PHE   B 2 227 ? 140.004 155.725 150.305 1.00 57.66  ? 289  PHE   R N   1 
ATOM   2425 C  CA  . PHE   B 2 227 ? 139.815 155.600 151.745 1.00 57.66  ? 289  PHE   R CA  1 
ATOM   2426 C  C   . PHE   B 2 227 ? 141.096 155.921 152.505 1.00 57.66  ? 289  PHE   R C   1 
ATOM   2427 O  O   . PHE   B 2 227 ? 141.051 156.539 153.573 1.00 57.66  ? 289  PHE   R O   1 
ATOM   2428 C  CB  . PHE   B 2 227 ? 139.328 154.199 152.105 1.00 57.66  ? 289  PHE   R CB  1 
ATOM   2429 C  CG  . PHE   B 2 227 ? 139.118 154.001 153.576 1.00 57.66  ? 289  PHE   R CG  1 
ATOM   2430 C  CD1 . PHE   B 2 227 ? 138.027 154.568 154.212 1.00 57.66  ? 289  PHE   R CD1 1 
ATOM   2431 C  CD2 . PHE   B 2 227 ? 140.020 153.267 154.328 1.00 57.66  ? 289  PHE   R CD2 1 
ATOM   2432 C  CE1 . PHE   B 2 227 ? 137.832 154.398 155.567 1.00 57.66  ? 289  PHE   R CE1 1 
ATOM   2433 C  CE2 . PHE   B 2 227 ? 139.831 153.094 155.684 1.00 57.66  ? 289  PHE   R CE2 1 
ATOM   2434 C  CZ  . PHE   B 2 227 ? 138.735 153.660 156.304 1.00 57.66  ? 289  PHE   R CZ  1 
ATOM   2435 N  N   . ILE   B 2 228 ? 142.247 155.509 151.972 1.00 53.66  ? 290  ILE   R N   1 
ATOM   2436 C  CA  . ILE   B 2 228 ? 143.508 155.776 152.664 1.00 53.66  ? 290  ILE   R CA  1 
ATOM   2437 C  C   . ILE   B 2 228 ? 143.868 157.255 152.618 1.00 53.66  ? 290  ILE   R C   1 
ATOM   2438 O  O   . ILE   B 2 228 ? 144.397 157.806 153.596 1.00 53.66  ? 290  ILE   R O   1 
ATOM   2439 C  CB  . ILE   B 2 228 ? 144.623 154.874 152.107 1.00 53.66  ? 290  ILE   R CB  1 
ATOM   2440 C  CG1 . ILE   B 2 228 ? 144.259 153.443 152.444 1.00 53.66  ? 290  ILE   R CG1 1 
ATOM   2441 C  CG2 . ILE   B 2 228 ? 145.970 155.201 152.702 1.00 53.66  ? 290  ILE   R CG2 1 
ATOM   2442 C  CD1 . ILE   B 2 228 ? 143.997 153.300 153.914 1.00 53.66  ? 290  ILE   R CD1 1 
ATOM   2443 N  N   . VAL   B 2 229 ? 143.581 157.924 151.499 1.00 54.47  ? 291  VAL   R N   1 
ATOM   2444 C  CA  . VAL   B 2 229 ? 143.795 159.371 151.437 1.00 54.47  ? 291  VAL   R CA  1 
ATOM   2445 C  C   . VAL   B 2 229 ? 142.940 160.077 152.485 1.00 54.47  ? 291  VAL   R C   1 
ATOM   2446 O  O   . VAL   B 2 229 ? 143.428 160.938 153.234 1.00 54.47  ? 291  VAL   R O   1 
ATOM   2447 C  CB  . VAL   B 2 229 ? 143.511 159.902 150.022 1.00 54.47  ? 291  VAL   R CB  1 
ATOM   2448 C  CG1 . VAL   B 2 229 ? 143.632 161.414 149.994 1.00 54.47  ? 291  VAL   R CG1 1 
ATOM   2449 C  CG2 . VAL   B 2 229 ? 144.473 159.286 149.027 1.00 54.47  ? 291  VAL   R CG2 1 
ATOM   2450 N  N   . TYR   B 2 230 ? 141.665 159.679 152.588 1.00 55.65  ? 292  TYR   R N   1 
ATOM   2451 C  CA  . TYR   B 2 230 ? 140.776 160.265 153.591 1.00 55.65  ? 292  TYR   R CA  1 
ATOM   2452 C  C   . TYR   B 2 230 ? 141.274 160.004 155.010 1.00 55.65  ? 292  TYR   R C   1 
ATOM   2453 O  O   . TYR   B 2 230 ? 141.263 160.909 155.857 1.00 55.65  ? 292  TYR   R O   1 
ATOM   2454 C  CB  . TYR   B 2 230 ? 139.363 159.711 153.420 1.00 55.65  ? 292  TYR   R CB  1 
ATOM   2455 C  CG  . TYR   B 2 230 ? 138.433 160.023 154.570 1.00 55.65  ? 292  TYR   R CG  1 
ATOM   2456 C  CD1 . TYR   B 2 230 ? 137.899 161.296 154.727 1.00 55.65  ? 292  TYR   R CD1 1 
ATOM   2457 C  CD2 . TYR   B 2 230 ? 138.081 159.046 155.493 1.00 55.65  ? 292  TYR   R CD2 1 
ATOM   2458 C  CE1 . TYR   B 2 230 ? 137.045 161.589 155.773 1.00 55.65  ? 292  TYR   R CE1 1 
ATOM   2459 C  CE2 . TYR   B 2 230 ? 137.228 159.330 156.543 1.00 55.65  ? 292  TYR   R CE2 1 
ATOM   2460 C  CZ  . TYR   B 2 230 ? 136.713 160.603 156.676 1.00 55.65  ? 292  TYR   R CZ  1 
ATOM   2461 O  OH  . TYR   B 2 230 ? 135.863 160.890 157.719 1.00 55.65  ? 292  TYR   R OH  1 
ATOM   2462 N  N   . ALA   B 2 231 ? 141.723 158.776 155.281 1.00 51.81  ? 293  ALA   R N   1 
ATOM   2463 C  CA  . ALA   B 2 231 ? 142.155 158.410 156.626 1.00 51.81  ? 293  ALA   R CA  1 
ATOM   2464 C  C   . ALA   B 2 231 ? 143.403 159.171 157.044 1.00 51.81  ? 293  ALA   R C   1 
ATOM   2465 O  O   . ALA   B 2 231 ? 143.478 159.666 158.174 1.00 51.81  ? 293  ALA   R O   1 
ATOM   2466 C  CB  . ALA   B 2 231 ? 142.400 156.906 156.706 1.00 51.81  ? 293  ALA   R CB  1 
ATOM   2467 N  N   . TYR   B 2 232 ? 144.389 159.283 156.152 1.00 49.43  ? 294  TYR   R N   1 
ATOM   2468 C  CA  . TYR   B 2 232 ? 145.602 160.017 156.498 1.00 49.43  ? 294  TYR   R CA  1 
ATOM   2469 C  C   . TYR   B 2 232 ? 145.320 161.503 156.665 1.00 49.43  ? 294  TYR   R C   1 
ATOM   2470 O  O   . TYR   B 2 232 ? 145.900 162.151 157.549 1.00 49.43  ? 294  TYR   R O   1 
ATOM   2471 C  CB  . TYR   B 2 232 ? 146.680 159.794 155.443 1.00 49.43  ? 294  TYR   R CB  1 
ATOM   2472 C  CG  . TYR   B 2 232 ? 147.518 158.571 155.703 1.00 49.43  ? 294  TYR   R CG  1 
ATOM   2473 C  CD1 . TYR   B 2 232 ? 148.104 158.357 156.940 1.00 49.43  ? 294  TYR   R CD1 1 
ATOM   2474 C  CD2 . TYR   B 2 232 ? 147.710 157.624 154.714 1.00 49.43  ? 294  TYR   R CD2 1 
ATOM   2475 C  CE1 . TYR   B 2 232 ? 148.865 157.235 157.179 1.00 49.43  ? 294  TYR   R CE1 1 
ATOM   2476 C  CE2 . TYR   B 2 232 ? 148.466 156.503 154.943 1.00 49.43  ? 294  TYR   R CE2 1 
ATOM   2477 C  CZ  . TYR   B 2 232 ? 149.040 156.313 156.173 1.00 49.43  ? 294  TYR   R CZ  1 
ATOM   2478 O  OH  . TYR   B 2 232 ? 149.790 155.186 156.387 1.00 49.43  ? 294  TYR   R OH  1 
ATOM   2479 N  N   . MET   B 2 233 ? 144.423 162.058 155.838 1.00 58.13  ? 295  MET   R N   1 
ATOM   2480 C  CA  . MET   B 2 233 ? 144.055 163.461 155.996 1.00 58.13  ? 295  MET   R CA  1 
ATOM   2481 C  C   . MET   B 2 233 ? 143.398 163.711 157.346 1.00 58.13  ? 295  MET   R C   1 
ATOM   2482 O  O   . MET   B 2 233 ? 143.737 164.680 158.035 1.00 58.13  ? 295  MET   R O   1 
ATOM   2483 C  CB  . MET   B 2 233 ? 143.131 163.894 154.860 1.00 58.13  ? 295  MET   R CB  1 
ATOM   2484 C  CG  . MET   B 2 233 ? 143.859 164.231 153.569 1.00 58.13  ? 295  MET   R CG  1 
ATOM   2485 S  SD  . MET   B 2 233 ? 144.921 165.681 153.719 1.00 58.13  ? 295  MET   R SD  1 
ATOM   2486 C  CE  . MET   B 2 233 ? 146.531 164.960 153.410 1.00 58.13  ? 295  MET   R CE  1 
ATOM   2487 N  N   . TYR   B 2 234 ? 142.489 162.823 157.760 1.00 55.13  ? 296  TYR   R N   1 
ATOM   2488 C  CA  . TYR   B 2 234 ? 141.835 162.987 159.056 1.00 55.13  ? 296  TYR   R CA  1 
ATOM   2489 C  C   . TYR   B 2 234 ? 142.817 162.822 160.211 1.00 55.13  ? 296  TYR   R C   1 
ATOM   2490 O  O   . TYR   B 2 234 ? 142.750 163.569 161.196 1.00 55.13  ? 296  TYR   R O   1 
ATOM   2491 C  CB  . TYR   B 2 234 ? 140.683 161.998 159.196 1.00 55.13  ? 296  TYR   R CB  1 
ATOM   2492 C  CG  . TYR   B 2 234 ? 140.179 161.858 160.612 1.00 55.13  ? 296  TYR   R CG  1 
ATOM   2493 C  CD1 . TYR   B 2 234 ? 139.534 162.909 161.249 1.00 55.13  ? 296  TYR   R CD1 1 
ATOM   2494 C  CD2 . TYR   B 2 234 ? 140.351 160.675 161.315 1.00 55.13  ? 296  TYR   R CD2 1 
ATOM   2495 C  CE1 . TYR   B 2 234 ? 139.074 162.784 162.544 1.00 55.13  ? 296  TYR   R CE1 1 
ATOM   2496 C  CE2 . TYR   B 2 234 ? 139.894 160.541 162.608 1.00 55.13  ? 296  TYR   R CE2 1 
ATOM   2497 C  CZ  . TYR   B 2 234 ? 139.257 161.597 163.217 1.00 55.13  ? 296  TYR   R CZ  1 
ATOM   2498 O  OH  . TYR   B 2 234 ? 138.801 161.458 164.506 1.00 55.13  ? 296  TYR   R OH  1 
ATOM   2499 N  N   . ILE   B 2 235 ? 143.732 161.851 160.109 1.00 51.65  ? 297  ILE   R N   1 
ATOM   2500 C  CA  . ILE   B 2 235 ? 144.702 161.613 161.176 1.00 51.65  ? 297  ILE   R CA  1 
ATOM   2501 C  C   . ILE   B 2 235 ? 145.619 162.818 161.347 1.00 51.65  ? 297  ILE   R C   1 
ATOM   2502 O  O   . ILE   B 2 235 ? 145.872 163.268 162.469 1.00 51.65  ? 297  ILE   R O   1 
ATOM   2503 C  CB  . ILE   B 2 235 ? 145.505 160.328 160.897 1.00 51.65  ? 297  ILE   R CB  1 
ATOM   2504 C  CG1 . ILE   B 2 235 ? 144.653 159.091 161.162 1.00 51.65  ? 297  ILE   R CG1 1 
ATOM   2505 C  CG2 . ILE   B 2 235 ? 146.760 160.264 161.751 1.00 51.65  ? 297  ILE   R CG2 1 
ATOM   2506 C  CD1 . ILE   B 2 235 ? 145.124 157.867 160.413 1.00 51.65  ? 297  ILE   R CD1 1 
ATOM   2507 N  N   . LEU   B 2 236 ? 146.110 163.377 160.240 1.00 52.61  ? 298  LEU   R N   1 
ATOM   2508 C  CA  . LEU   B 2 236 ? 147.016 164.517 160.352 1.00 52.61  ? 298  LEU   R CA  1 
ATOM   2509 C  C   . LEU   B 2 236 ? 146.269 165.787 160.743 1.00 52.61  ? 298  LEU   R C   1 
ATOM   2510 O  O   . LEU   B 2 236 ? 146.839 166.674 161.389 1.00 52.61  ? 298  LEU   R O   1 
ATOM   2511 C  CB  . LEU   B 2 236 ? 147.787 164.731 159.049 1.00 52.61  ? 298  LEU   R CB  1 
ATOM   2512 C  CG  . LEU   B 2 236 ? 149.109 163.983 158.837 1.00 52.61  ? 298  LEU   R CG  1 
ATOM   2513 C  CD1 . LEU   B 2 236 ? 150.120 164.394 159.890 1.00 52.61  ? 298  LEU   R CD1 1 
ATOM   2514 C  CD2 . LEU   B 2 236 ? 148.946 162.478 158.810 1.00 52.61  ? 298  LEU   R CD2 1 
ATOM   2515 N  N   . TRP   B 2 237 ? 144.994 165.903 160.358 1.00 54.65  ? 299  TRP   R N   1 
ATOM   2516 C  CA  . TRP   B 2 237 ? 144.247 167.109 160.699 1.00 54.65  ? 299  TRP   R CA  1 
ATOM   2517 C  C   . TRP   B 2 237 ? 143.873 167.140 162.174 1.00 54.65  ? 299  TRP   R C   1 
ATOM   2518 O  O   . TRP   B 2 237 ? 144.031 168.171 162.836 1.00 54.65  ? 299  TRP   R O   1 
ATOM   2519 C  CB  . TRP   B 2 237 ? 142.995 167.221 159.836 1.00 54.65  ? 299  TRP   R CB  1 
ATOM   2520 C  CG  . TRP   B 2 237 ? 141.962 168.119 160.437 1.00 54.65  ? 299  TRP   R CG  1 
ATOM   2521 C  CD1 . TRP   B 2 237 ? 141.997 169.480 160.492 1.00 54.65  ? 299  TRP   R CD1 1 
ATOM   2522 C  CD2 . TRP   B 2 237 ? 140.739 167.723 161.065 1.00 54.65  ? 299  TRP   R CD2 1 
ATOM   2523 N  NE1 . TRP   B 2 237 ? 140.873 169.957 161.118 1.00 54.65  ? 299  TRP   R NE1 1 
ATOM   2524 C  CE2 . TRP   B 2 237 ? 140.084 168.897 161.480 1.00 54.65  ? 299  TRP   R CE2 1 
ATOM   2525 C  CE3 . TRP   B 2 237 ? 140.135 166.490 161.319 1.00 54.65  ? 299  TRP   R CE3 1 
ATOM   2526 C  CZ2 . TRP   B 2 237 ? 138.856 168.876 162.132 1.00 54.65  ? 299  TRP   R CZ2 1 
ATOM   2527 C  CZ3 . TRP   B 2 237 ? 138.916 166.470 161.967 1.00 54.65  ? 299  TRP   R CZ3 1 
ATOM   2528 C  CH2 . TRP   B 2 237 ? 138.289 167.655 162.365 1.00 54.65  ? 299  TRP   R CH2 1 
ATOM   2529 N  N   . LYS   B 2 238 ? 143.370 166.024 162.707 1.00 52.40  ? 300  LYS   R N   1 
ATOM   2530 C  CA  . LYS   B 2 238 ? 142.911 166.021 164.093 1.00 52.40  ? 300  LYS   R CA  1 
ATOM   2531 C  C   . LYS   B 2 238 ? 144.079 166.105 165.065 1.00 52.40  ? 300  LYS   R C   1 
ATOM   2532 O  O   . LYS   B 2 238 ? 143.956 166.685 166.148 1.00 52.40  ? 300  LYS   R O   1 
ATOM   2533 C  CB  . LYS   B 2 238 ? 142.076 164.774 164.370 1.00 52.40  ? 300  LYS   R CB  1 
ATOM   2534 C  CG  . LYS   B 2 238 ? 141.392 164.778 165.727 1.00 52.40  ? 300  LYS   R CG  1 
ATOM   2535 C  CD  . LYS   B 2 238 ? 140.878 163.403 166.093 1.00 52.40  ? 300  LYS   R CD  1 
ATOM   2536 C  CE  . LYS   B 2 238 ? 140.396 163.357 167.531 1.00 52.40  ? 300  LYS   R CE  1 
ATOM   2537 N  NZ  . LYS   B 2 238 ? 141.483 163.689 168.489 1.00 52.40  ? 300  LYS   R NZ  1 
ATOM   2538 N  N   . ALA   B 2 239 ? 145.222 165.532 164.697 1.00 52.40  ? 301  ALA   R N   1 
ATOM   2539 C  CA  . ALA   B 2 239 ? 146.360 165.528 165.606 1.00 52.40  ? 301  ALA   R CA  1 
ATOM   2540 C  C   . ALA   B 2 239 ? 147.062 166.876 165.627 1.00 52.40  ? 301  ALA   R C   1 
ATOM   2541 O  O   . ALA   B 2 239 ? 147.827 167.170 166.552 1.00 52.40  ? 301  ALA   R O   1 
ATOM   2542 C  CB  . ALA   B 2 239 ? 147.333 164.426 165.213 1.00 52.40  ? 301  ALA   R CB  1 
ATOM   2543 N  N   . GLY   B 2 240 ? 146.837 167.701 164.604 1.00 58.17  ? 1001 GLY   R N   1 
ATOM   2544 C  CA  . GLY   B 2 240 ? 147.405 169.038 164.612 1.00 58.17  ? 1001 GLY   R CA  1 
ATOM   2545 C  C   . GLY   B 2 240 ? 146.772 169.938 165.655 1.00 58.17  ? 1001 GLY   R C   1 
ATOM   2546 O  O   . GLY   B 2 240 ? 147.460 170.715 166.320 1.00 58.17  ? 1001 GLY   R O   1 
ATOM   2547 N  N   . ILE   B 2 241 ? 145.449 169.838 165.819 1.00 57.33  ? 1002 ILE   R N   1 
ATOM   2548 C  CA  . ILE   B 2 241 ? 144.726 170.724 166.728 1.00 57.33  ? 1002 ILE   R CA  1 
ATOM   2549 C  C   . ILE   B 2 241 ? 144.727 170.234 168.164 1.00 57.33  ? 1002 ILE   R C   1 
ATOM   2550 O  O   . ILE   B 2 241 ? 144.194 170.925 169.041 1.00 57.33  ? 1002 ILE   R O   1 
ATOM   2551 C  CB  . ILE   B 2 241 ? 143.264 170.905 166.275 1.00 57.33  ? 1002 ILE   R CB  1 
ATOM   2552 C  CG1 . ILE   B 2 241 ? 142.502 169.590 166.401 1.00 57.33  ? 1002 ILE   R CG1 1 
ATOM   2553 C  CG2 . ILE   B 2 241 ? 143.211 171.390 164.843 1.00 57.33  ? 1002 ILE   R CG2 1 
ATOM   2554 C  CD1 . ILE   B 2 241 ? 141.016 169.724 166.177 1.00 57.33  ? 1002 ILE   R CD1 1 
ATOM   2555 N  N   . ASP   B 2 242 ? 145.306 169.070 168.439 1.00 61.59  ? 1003 ASP   R N   1 
ATOM   2556 C  CA  . ASP   B 2 242 ? 145.241 168.480 169.767 1.00 61.59  ? 1003 ASP   R CA  1 
ATOM   2557 C  C   . ASP   B 2 242 ? 146.597 168.202 170.392 1.00 61.59  ? 1003 ASP   R C   1 
ATOM   2558 O  O   . ASP   B 2 242 ? 146.694 168.200 171.620 1.00 61.59  ? 1003 ASP   R O   1 
ATOM   2559 C  CB  . ASP   B 2 242 ? 144.441 167.171 169.728 1.00 61.59  ? 1003 ASP   R CB  1 
ATOM   2560 C  CG  . ASP   B 2 242 ? 142.950 167.400 169.840 1.00 61.59  ? 1003 ASP   R CG  1 
ATOM   2561 O  OD1 . ASP   B 2 242 ? 142.527 168.572 169.789 1.00 61.59  ? 1003 ASP   R OD1 1 
ATOM   2562 O  OD2 . ASP   B 2 242 ? 142.199 166.412 169.975 1.00 61.59  ? 1003 ASP   R OD2 1 
ATOM   2563 N  N   . CYS   B 2 243 ? 147.635 167.950 169.592 1.00 64.88  ? 1004 CYS   R N   1 
ATOM   2564 C  CA  . CYS   B 2 243 ? 148.954 167.673 170.155 1.00 64.88  ? 1004 CYS   R CA  1 
ATOM   2565 C  C   . CYS   B 2 243 ? 149.537 168.903 170.835 1.00 64.88  ? 1004 CYS   R C   1 
ATOM   2566 O  O   . CYS   B 2 243 ? 150.162 168.796 171.896 1.00 64.88  ? 1004 CYS   R O   1 
ATOM   2567 C  CB  . CYS   B 2 243 ? 149.899 167.168 169.066 1.00 64.88  ? 1004 CYS   R CB  1 
ATOM   2568 S  SG  . CYS   B 2 243 ? 151.620 167.013 169.582 1.00 64.88  ? 1004 CYS   R SG  1 
ATOM   2569 N  N   . SER   B 2 244 ? 149.341 170.076 170.248 1.00 62.60  ? 1005 SER   R N   1 
ATOM   2570 C  CA  . SER   B 2 244 ? 149.801 171.334 170.825 1.00 62.60  ? 1005 SER   R CA  1 
ATOM   2571 C  C   . SER   B 2 244 ? 148.565 172.129 171.235 1.00 62.60  ? 1005 SER   R C   1 
ATOM   2572 O  O   . SER   B 2 244 ? 148.047 172.943 170.470 1.00 62.60  ? 1005 SER   R O   1 
ATOM   2573 C  CB  . SER   B 2 244 ? 150.667 172.106 169.846 1.00 62.60  ? 1005 SER   R CB  1 
ATOM   2574 O  OG  . SER   B 2 244 ? 151.266 173.220 170.483 1.00 62.60  ? 1005 SER   R OG  1 
ATOM   2575 N  N   . PHE   B 2 245 ? 148.094 171.877 172.448 1.00 60.96  ? 1006 PHE   R N   1 
ATOM   2576 C  CA  . PHE   B 2 245 ? 146.971 172.592 173.037 1.00 60.96  ? 1006 PHE   R CA  1 
ATOM   2577 C  C   . PHE   B 2 245 ? 147.310 173.210 174.380 1.00 60.96  ? 1006 PHE   R C   1 
ATOM   2578 O  O   . PHE   B 2 245 ? 146.822 174.295 174.692 1.00 60.96  ? 1006 PHE   R O   1 
ATOM   2579 C  CB  . PHE   B 2 245 ? 145.776 171.647 173.205 1.00 60.96  ? 1006 PHE   R CB  1 
ATOM   2580 C  CG  . PHE   B 2 245 ? 144.456 172.347 173.331 1.00 60.96  ? 1006 PHE   R CG  1 
ATOM   2581 C  CD1 . PHE   B 2 245 ? 143.986 172.755 174.568 1.00 60.96  ? 1006 PHE   R CD1 1 
ATOM   2582 C  CD2 . PHE   B 2 245 ? 143.673 172.575 172.214 1.00 60.96  ? 1006 PHE   R CD2 1 
ATOM   2583 C  CE1 . PHE   B 2 245 ? 142.770 173.391 174.687 1.00 60.96  ? 1006 PHE   R CE1 1 
ATOM   2584 C  CE2 . PHE   B 2 245 ? 142.453 173.206 172.327 1.00 60.96  ? 1006 PHE   R CE2 1 
ATOM   2585 C  CZ  . PHE   B 2 245 ? 142.001 173.615 173.567 1.00 60.96  ? 1006 PHE   R CZ  1 
ATOM   2586 N  N   . TRP   B 2 246 ? 148.138 172.543 175.182 1.00 58.45  ? 1007 TRP   R N   1 
ATOM   2587 C  CA  . TRP   B 2 246 ? 148.497 173.019 176.514 1.00 58.45  ? 1007 TRP   R CA  1 
ATOM   2588 C  C   . TRP   B 2 246 ? 149.837 173.742 176.424 1.00 58.45  ? 1007 TRP   R C   1 
ATOM   2589 O  O   . TRP   B 2 246 ? 150.896 173.198 176.728 1.00 58.45  ? 1007 TRP   R O   1 
ATOM   2590 C  CB  . TRP   B 2 246 ? 148.535 171.857 177.496 1.00 58.45  ? 1007 TRP   R CB  1 
ATOM   2591 C  CG  . TRP   B 2 246 ? 147.256 171.085 177.528 1.00 58.45  ? 1007 TRP   R CG  1 
ATOM   2592 C  CD1 . TRP   B 2 246 ? 146.977 169.940 176.849 1.00 58.45  ? 1007 TRP   R CD1 1 
ATOM   2593 C  CD2 . TRP   B 2 246 ? 146.078 171.408 178.273 1.00 58.45  ? 1007 TRP   R CD2 1 
ATOM   2594 N  NE1 . TRP   B 2 246 ? 145.699 169.526 177.124 1.00 58.45  ? 1007 TRP   R NE1 1 
ATOM   2595 C  CE2 . TRP   B 2 246 ? 145.125 170.412 177.997 1.00 58.45  ? 1007 TRP   R CE2 1 
ATOM   2596 C  CE3 . TRP   B 2 246 ? 145.737 172.441 179.148 1.00 58.45  ? 1007 TRP   R CE3 1 
ATOM   2597 C  CZ2 . TRP   B 2 246 ? 143.857 170.417 178.565 1.00 58.45  ? 1007 TRP   R CZ2 1 
ATOM   2598 C  CZ3 . TRP   B 2 246 ? 144.478 172.445 179.709 1.00 58.45  ? 1007 TRP   R CZ3 1 
ATOM   2599 C  CH2 . TRP   B 2 246 ? 143.553 171.440 179.415 1.00 58.45  ? 1007 TRP   R CH2 1 
ATOM   2600 N  N   . ASN   B 2 247 ? 149.773 174.998 175.987 1.00 67.20  ? 1008 ASN   R N   1 
ATOM   2601 C  CA  . ASN   B 2 247 ? 150.947 175.840 175.824 1.00 67.20  ? 1008 ASN   R CA  1 
ATOM   2602 C  C   . ASN   B 2 247 ? 150.544 177.290 176.040 1.00 67.20  ? 1008 ASN   R C   1 
ATOM   2603 O  O   . ASN   B 2 247 ? 149.410 177.678 175.753 1.00 67.20  ? 1008 ASN   R O   1 
ATOM   2604 C  CB  . ASN   B 2 247 ? 151.571 175.661 174.434 1.00 67.20  ? 1008 ASN   R CB  1 
ATOM   2605 C  CG  . ASN   B 2 247 ? 152.988 176.182 174.359 1.00 67.20  ? 1008 ASN   R CG  1 
ATOM   2606 O  OD1 . ASN   B 2 247 ? 153.216 177.342 174.017 1.00 67.20  ? 1008 ASN   R OD1 1 
ATOM   2607 N  ND2 . ASN   B 2 247 ? 153.951 175.327 174.679 1.00 67.20  ? 1008 ASN   R ND2 1 
ATOM   2608 N  N   . GLU   B 2 248 ? 151.478 178.093 176.554 1.00 67.56  ? 1009 GLU   R N   1 
ATOM   2609 C  CA  . GLU   B 2 248 ? 151.183 179.497 176.817 1.00 67.56  ? 1009 GLU   R CA  1 
ATOM   2610 C  C   . GLU   B 2 248 ? 151.134 180.352 175.560 1.00 67.56  ? 1009 GLU   R C   1 
ATOM   2611 O  O   . GLU   B 2 248 ? 150.789 181.535 175.657 1.00 67.56  ? 1009 GLU   R O   1 
ATOM   2612 C  CB  . GLU   B 2 248 ? 152.199 180.106 177.783 1.00 67.56  ? 1009 GLU   R CB  1 
ATOM   2613 C  CG  . GLU   B 2 248 ? 152.078 179.634 179.215 1.00 67.56  ? 1009 GLU   R CG  1 
ATOM   2614 C  CD  . GLU   B 2 248 ? 153.086 180.307 180.125 1.00 67.56  ? 1009 GLU   R CD  1 
ATOM   2615 O  OE1 . GLU   B 2 248 ? 153.967 181.022 179.607 1.00 67.56  ? 1009 GLU   R OE1 1 
ATOM   2616 O  OE2 . GLU   B 2 248 ? 152.997 180.132 181.357 1.00 67.56  ? 1009 GLU   R OE2 1 
ATOM   2617 N  N   . SER   B 2 249 ? 151.475 179.799 174.393 1.00 68.38  ? 1010 SER   R N   1 
ATOM   2618 C  CA  . SER   B 2 249 ? 151.398 180.559 173.151 1.00 68.38  ? 1010 SER   R CA  1 
ATOM   2619 C  C   . SER   B 2 249 ? 149.969 180.939 172.784 1.00 68.38  ? 1010 SER   R C   1 
ATOM   2620 O  O   . SER   B 2 249 ? 149.772 181.882 172.012 1.00 68.38  ? 1010 SER   R O   1 
ATOM   2621 C  CB  . SER   B 2 249 ? 152.037 179.764 172.013 1.00 68.38  ? 1010 SER   R CB  1 
ATOM   2622 O  OG  . SER   B 2 249 ? 151.363 178.536 171.809 1.00 68.38  ? 1010 SER   R OG  1 
ATOM   2623 N  N   . TYR   B 2 250 ? 148.975 180.233 173.312 1.00 66.15  ? 1011 TYR   R N   1 
ATOM   2624 C  CA  . TYR   B 2 250 ? 147.577 180.574 173.102 1.00 66.15  ? 1011 TYR   R CA  1 
ATOM   2625 C  C   . TYR   B 2 250 ? 147.019 181.462 174.203 1.00 66.15  ? 1011 TYR   R C   1 
ATOM   2626 O  O   . TYR   B 2 250 ? 145.828 181.786 174.174 1.00 66.15  ? 1011 TYR   R O   1 
ATOM   2627 C  CB  . TYR   B 2 250 ? 146.738 179.299 172.998 1.00 66.15  ? 1011 TYR   R CB  1 
ATOM   2628 C  CG  . TYR   B 2 250 ? 147.453 178.173 172.292 1.00 66.15  ? 1011 TYR   R CG  1 
ATOM   2629 C  CD1 . TYR   B 2 250 ? 147.648 178.203 170.920 1.00 66.15  ? 1011 TYR   R CD1 1 
ATOM   2630 C  CD2 . TYR   B 2 250 ? 147.950 177.090 173.003 1.00 66.15  ? 1011 TYR   R CD2 1 
ATOM   2631 C  CE1 . TYR   B 2 250 ? 148.306 177.181 170.274 1.00 66.15  ? 1011 TYR   R CE1 1 
ATOM   2632 C  CE2 . TYR   B 2 250 ? 148.613 176.064 172.367 1.00 66.15  ? 1011 TYR   R CE2 1 
ATOM   2633 C  CZ  . TYR   B 2 250 ? 148.788 176.114 171.003 1.00 66.15  ? 1011 TYR   R CZ  1 
ATOM   2634 O  OH  . TYR   B 2 250 ? 149.447 175.093 170.364 1.00 66.15  ? 1011 TYR   R OH  1 
ATOM   2635 N  N   . LEU   B 2 251 ? 147.843 181.859 175.167 1.00 68.02  ? 1012 LEU   R N   1 
ATOM   2636 C  CA  . LEU   B 2 251 ? 147.416 182.702 176.275 1.00 68.02  ? 1012 LEU   R CA  1 
ATOM   2637 C  C   . LEU   B 2 251 ? 148.063 184.074 176.154 1.00 68.02  ? 1012 LEU   R C   1 
ATOM   2638 O  O   . LEU   B 2 251 ? 149.289 184.182 176.040 1.00 68.02  ? 1012 LEU   R O   1 
ATOM   2639 C  CB  . LEU   B 2 251 ? 147.772 182.062 177.618 1.00 68.02  ? 1012 LEU   R CB  1 
ATOM   2640 C  CG  . LEU   B 2 251 ? 146.902 180.880 178.041 1.00 68.02  ? 1012 LEU   R CG  1 
ATOM   2641 C  CD1 . LEU   B 2 251 ? 147.233 180.458 179.457 1.00 68.02  ? 1012 LEU   R CD1 1 
ATOM   2642 C  CD2 . LEU   B 2 251 ? 145.426 181.222 177.909 1.00 68.02  ? 1012 LEU   R CD2 1 
ATOM   2643 N  N   . THR   B 2 252 ? 147.237 185.116 176.183 1.00 73.67  ? 1013 THR   R N   1 
ATOM   2644 C  CA  . THR   B 2 252 ? 147.710 186.484 176.069 1.00 73.67  ? 1013 THR   R CA  1 
ATOM   2645 C  C   . THR   B 2 252 ? 148.086 187.026 177.445 1.00 73.67  ? 1013 THR   R C   1 
ATOM   2646 O  O   . THR   B 2 252 ? 147.973 186.344 178.465 1.00 73.67  ? 1013 THR   R O   1 
ATOM   2647 C  CB  . THR   B 2 252 ? 146.648 187.363 175.415 1.00 73.67  ? 1013 THR   R CB  1 
ATOM   2648 O  OG1 . THR   B 2 252 ? 145.470 187.373 176.230 1.00 73.67  ? 1013 THR   R OG1 1 
ATOM   2649 C  CG2 . THR   B 2 252 ? 146.295 186.828 174.039 1.00 73.67  ? 1013 THR   R CG2 1 
ATOM   2650 N  N   . GLY   B 2 253 ? 148.537 188.277 177.473 1.00 72.79  ? 1014 GLY   R N   1 
ATOM   2651 C  CA  . GLY   B 2 253 ? 148.862 188.914 178.729 1.00 72.79  ? 1014 GLY   R CA  1 
ATOM   2652 C  C   . GLY   B 2 253 ? 150.138 188.364 179.344 1.00 72.79  ? 1014 GLY   R C   1 
ATOM   2653 O  O   . GLY   B 2 253 ? 150.991 187.772 178.680 1.00 72.79  ? 1014 GLY   R O   1 
ATOM   2654 N  N   . SER   B 2 254 ? 150.251 188.570 180.654 1.00 69.15  ? 1015 SER   R N   1 
ATOM   2655 C  CA  . SER   B 2 254 ? 151.396 188.092 181.416 1.00 69.15  ? 1015 SER   R CA  1 
ATOM   2656 C  C   . SER   B 2 254 ? 150.920 187.258 182.596 1.00 69.15  ? 1015 SER   R C   1 
ATOM   2657 O  O   . SER   B 2 254 ? 149.741 186.901 182.670 1.00 69.15  ? 1015 SER   R O   1 
ATOM   2658 C  CB  . SER   B 2 254 ? 152.257 189.260 181.892 1.00 69.15  ? 1015 SER   R CB  1 
ATOM   2659 O  OG  . SER   B 2 254 ? 151.557 190.047 182.835 1.00 69.15  ? 1015 SER   R OG  1 
ATOM   2660 N  N   . ARG   B 2 255 ? 151.828 186.931 183.515 1.00 65.57  ? 1016 ARG   R N   1 
ATOM   2661 C  CA  . ARG   B 2 255 ? 151.472 186.065 184.634 1.00 65.57  ? 1016 ARG   R CA  1 
ATOM   2662 C  C   . ARG   B 2 255 ? 150.619 186.800 185.661 1.00 65.57  ? 1016 ARG   R C   1 
ATOM   2663 O  O   . ARG   B 2 255 ? 149.481 186.402 185.945 1.00 65.57  ? 1016 ARG   R O   1 
ATOM   2664 C  CB  . ARG   B 2 255 ? 152.740 185.510 185.286 1.00 65.57  ? 1016 ARG   R CB  1 
ATOM   2665 C  CG  . ARG   B 2 255 ? 152.475 184.401 186.281 1.00 65.57  ? 1016 ARG   R CG  1 
ATOM   2666 C  CD  . ARG   B 2 255 ? 151.621 183.320 185.655 1.00 65.57  ? 1016 ARG   R CD  1 
ATOM   2667 N  NE  . ARG   B 2 255 ? 151.586 182.104 186.456 1.00 65.57  ? 1016 ARG   R NE  1 
ATOM   2668 C  CZ  . ARG   B 2 255 ? 152.301 181.020 186.198 1.00 65.57  ? 1016 ARG   R CZ  1 
ATOM   2669 N  NH1 . ARG   B 2 255 ? 153.150 180.977 185.186 1.00 65.57  ? 1016 ARG   R NH1 1 
ATOM   2670 N  NH2 . ARG   B 2 255 ? 152.156 179.950 186.971 1.00 65.57  ? 1016 ARG   R NH2 1 
ATOM   2671 N  N   . ASP   B 2 256 ? 151.160 187.881 186.231 1.00 72.44  ? 1017 ASP   R N   1 
ATOM   2672 C  CA  . ASP   B 2 256 ? 150.500 188.551 187.347 1.00 72.44  ? 1017 ASP   R CA  1 
ATOM   2673 C  C   . ASP   B 2 256 ? 149.214 189.238 186.909 1.00 72.44  ? 1017 ASP   R C   1 
ATOM   2674 O  O   . ASP   B 2 256 ? 148.240 189.276 187.668 1.00 72.44  ? 1017 ASP   R O   1 
ATOM   2675 C  CB  . ASP   B 2 256 ? 151.456 189.554 187.987 1.00 72.44  ? 1017 ASP   R CB  1 
ATOM   2676 C  CG  . ASP   B 2 256 ? 152.798 188.940 188.322 1.00 72.44  ? 1017 ASP   R CG  1 
ATOM   2677 O  OD1 . ASP   B 2 256 ? 152.928 188.355 189.417 1.00 72.44  ? 1017 ASP   R OD1 1 
ATOM   2678 O  OD2 . ASP   B 2 256 ? 153.720 189.031 187.484 1.00 72.44  ? 1017 ASP   R OD2 1 
ATOM   2679 N  N   . GLU   B 2 257 ? 149.191 189.779 185.691 1.00 71.98  ? 1018 GLU   R N   1 
ATOM   2680 C  CA  . GLU   B 2 257 ? 147.980 190.412 185.179 1.00 71.98  ? 1018 GLU   R CA  1 
ATOM   2681 C  C   . GLU   B 2 257 ? 146.855 189.398 185.000 1.00 71.98  ? 1018 GLU   R C   1 
ATOM   2682 O  O   . GLU   B 2 257 ? 145.705 189.667 185.370 1.00 71.98  ? 1018 GLU   R O   1 
ATOM   2683 C  CB  . GLU   B 2 257 ? 148.276 191.134 183.861 1.00 71.98  ? 1018 GLU   R CB  1 
ATOM   2684 C  CG  . GLU   B 2 257 ? 149.014 192.486 183.972 1.00 71.98  ? 1018 GLU   R CG  1 
ATOM   2685 C  CD  . GLU   B 2 257 ? 150.336 192.431 184.722 1.00 71.98  ? 1018 GLU   R CD  1 
ATOM   2686 O  OE1 . GLU   B 2 257 ? 151.083 191.446 184.551 1.00 71.98  ? 1018 GLU   R OE1 1 
ATOM   2687 O  OE2 . GLU   B 2 257 ? 150.627 193.375 185.485 1.00 71.98  ? 1018 GLU   R OE2 1 
ATOM   2688 N  N   . ARG   B 2 258 ? 147.173 188.221 184.454 1.00 68.08  ? 1019 ARG   R N   1 
ATOM   2689 C  CA  . ARG   B 2 258 ? 146.165 187.177 184.297 1.00 68.08  ? 1019 ARG   R CA  1 
ATOM   2690 C  C   . ARG   B 2 258 ? 145.696 186.653 185.647 1.00 68.08  ? 1019 ARG   R C   1 
ATOM   2691 O  O   . ARG   B 2 258 ? 144.504 186.380 185.831 1.00 68.08  ? 1019 ARG   R O   1 
ATOM   2692 C  CB  . ARG   B 2 258 ? 146.715 186.035 183.446 1.00 68.08  ? 1019 ARG   R CB  1 
ATOM   2693 C  CG  . ARG   B 2 258 ? 146.502 186.209 181.956 1.00 68.08  ? 1019 ARG   R CG  1 
ATOM   2694 C  CD  . ARG   B 2 258 ? 146.775 184.912 181.219 1.00 68.08  ? 1019 ARG   R CD  1 
ATOM   2695 N  NE  . ARG   B 2 258 ? 148.035 184.309 181.636 1.00 68.08  ? 1019 ARG   R NE  1 
ATOM   2696 C  CZ  . ARG   B 2 258 ? 149.086 184.150 180.846 1.00 68.08  ? 1019 ARG   R CZ  1 
ATOM   2697 N  NH1 . ARG   B 2 258 ? 149.064 184.533 179.581 1.00 68.08  ? 1019 ARG   R NH1 1 
ATOM   2698 N  NH2 . ARG   B 2 258 ? 150.189 183.592 181.337 1.00 68.08  ? 1019 ARG   R NH2 1 
ATOM   2699 N  N   . LYS   B 2 259 ? 146.621 186.507 186.602 1.00 68.03  ? 1020 LYS   R N   1 
ATOM   2700 C  CA  . LYS   B 2 259 ? 146.241 186.063 187.941 1.00 68.03  ? 1020 LYS   R CA  1 
ATOM   2701 C  C   . LYS   B 2 259 ? 145.323 187.072 188.621 1.00 68.03  ? 1020 LYS   R C   1 
ATOM   2702 O  O   . LYS   B 2 259 ? 144.329 186.691 189.253 1.00 68.03  ? 1020 LYS   R O   1 
ATOM   2703 C  CB  . LYS   B 2 259 ? 147.492 185.823 188.785 1.00 68.03  ? 1020 LYS   R CB  1 
ATOM   2704 C  CG  . LYS   B 2 259 ? 147.214 185.649 190.264 1.00 68.03  ? 1020 LYS   R CG  1 
ATOM   2705 C  CD  . LYS   B 2 259 ? 148.326 184.887 190.944 1.00 68.03  ? 1020 LYS   R CD  1 
ATOM   2706 C  CE  . LYS   B 2 259 ? 149.496 185.799 191.256 1.00 68.03  ? 1020 LYS   R CE  1 
ATOM   2707 N  NZ  . LYS   B 2 259 ? 150.464 185.154 192.181 1.00 68.03  ? 1020 LYS   R NZ  1 
ATOM   2708 N  N   . LYS   B 2 260 ? 145.635 188.365 188.489 1.00 72.50  ? 1021 LYS   R N   1 
ATOM   2709 C  CA  . LYS   B 2 260 ? 144.804 189.409 189.078 1.00 72.50  ? 1021 LYS   R CA  1 
ATOM   2710 C  C   . LYS   B 2 260 ? 143.426 189.448 188.434 1.00 72.50  ? 1021 LYS   R C   1 
ATOM   2711 O  O   . LYS   B 2 260 ? 142.416 189.610 189.129 1.00 72.50  ? 1021 LYS   R O   1 
ATOM   2712 C  CB  . LYS   B 2 260 ? 145.498 190.761 188.943 1.00 72.50  ? 1021 LYS   R CB  1 
ATOM   2713 C  CG  . LYS   B 2 260 ? 144.706 191.933 189.482 1.00 72.50  ? 1021 LYS   R CG  1 
ATOM   2714 C  CD  . LYS   B 2 260 ? 145.211 193.243 188.904 1.00 72.50  ? 1021 LYS   R CD  1 
ATOM   2715 C  CE  . LYS   B 2 260 ? 146.518 193.662 189.556 1.00 72.50  ? 1021 LYS   R CE  1 
ATOM   2716 N  NZ  . LYS   B 2 260 ? 146.312 194.174 190.938 1.00 72.50  ? 1021 LYS   R NZ  1 
ATOM   2717 N  N   . SER   B 2 261 ? 143.362 189.291 187.108 1.00 72.74  ? 1022 SER   R N   1 
ATOM   2718 C  CA  . SER   B 2 261 ? 142.070 189.262 186.428 1.00 72.74  ? 1022 SER   R CA  1 
ATOM   2719 C  C   . SER   B 2 261 ? 141.246 188.048 186.844 1.00 72.74  ? 1022 SER   R C   1 
ATOM   2720 O  O   . SER   B 2 261 ? 140.028 188.155 187.033 1.00 72.74  ? 1022 SER   R O   1 
ATOM   2721 C  CB  . SER   B 2 261 ? 142.274 189.280 184.914 1.00 72.74  ? 1022 SER   R CB  1 
ATOM   2722 O  OG  . SER   B 2 261 ? 141.030 189.261 184.236 1.00 72.74  ? 1022 SER   R OG  1 
ATOM   2723 N  N   . LEU   B 2 262 ? 141.893 186.890 187.002 1.00 70.27  ? 1023 LEU   R N   1 
ATOM   2724 C  CA  . LEU   B 2 262 ? 141.187 185.688 187.436 1.00 70.27  ? 1023 LEU   R CA  1 
ATOM   2725 C  C   . LEU   B 2 262 ? 140.677 185.820 188.866 1.00 70.27  ? 1023 LEU   R C   1 
ATOM   2726 O  O   . LEU   B 2 262 ? 139.548 185.416 189.168 1.00 70.27  ? 1023 LEU   R O   1 
ATOM   2727 C  CB  . LEU   B 2 262 ? 142.104 184.474 187.309 1.00 70.27  ? 1023 LEU   R CB  1 
ATOM   2728 C  CG  . LEU   B 2 262 ? 141.513 183.112 187.666 1.00 70.27  ? 1023 LEU   R CG  1 
ATOM   2729 C  CD1 . LEU   B 2 262 ? 140.741 182.540 186.488 1.00 70.27  ? 1023 LEU   R CD1 1 
ATOM   2730 C  CD2 . LEU   B 2 262 ? 142.615 182.165 188.106 1.00 70.27  ? 1023 LEU   R CD2 1 
ATOM   2731 N  N   . LEU   B 2 263 ? 141.493 186.380 189.762 1.00 68.95  ? 1024 LEU   R N   1 
ATOM   2732 C  CA  . LEU   B 2 263 ? 141.074 186.516 191.152 1.00 68.95  ? 1024 LEU   R CA  1 
ATOM   2733 C  C   . LEU   B 2 263 ? 140.004 187.586 191.318 1.00 68.95  ? 1024 LEU   R C   1 
ATOM   2734 O  O   . LEU   B 2 263 ? 139.118 187.444 192.168 1.00 68.95  ? 1024 LEU   R O   1 
ATOM   2735 C  CB  . LEU   B 2 263 ? 142.284 186.816 192.036 1.00 68.95  ? 1024 LEU   R CB  1 
ATOM   2736 C  CG  . LEU   B 2 263 ? 143.122 185.587 192.399 1.00 68.95  ? 1024 LEU   R CG  1 
ATOM   2737 C  CD1 . LEU   B 2 263 ? 144.440 185.985 193.033 1.00 68.95  ? 1024 LEU   R CD1 1 
ATOM   2738 C  CD2 . LEU   B 2 263 ? 142.344 184.667 193.320 1.00 68.95  ? 1024 LEU   R CD2 1 
ATOM   2739 N  N   . SER   B 2 264 ? 140.063 188.658 190.523 1.00 74.27  ? 1025 SER   R N   1 
ATOM   2740 C  CA  . SER   B 2 264 ? 138.975 189.629 190.510 1.00 74.27  ? 1025 SER   R CA  1 
ATOM   2741 C  C   . SER   B 2 264 ? 137.706 189.031 189.923 1.00 74.27  ? 1025 SER   R C   1 
ATOM   2742 O  O   . SER   B 2 264 ? 136.601 189.418 190.318 1.00 74.27  ? 1025 SER   R O   1 
ATOM   2743 C  CB  . SER   B 2 264 ? 139.388 190.868 189.720 1.00 74.27  ? 1025 SER   R CB  1 
ATOM   2744 O  OG  . SER   B 2 264 ? 139.564 190.555 188.350 1.00 74.27  ? 1025 SER   R OG  1 
ATOM   2745 N  N   . LYS   B 2 265 ? 137.844 188.100 188.974 1.00 75.47  ? 1026 LYS   R N   1 
ATOM   2746 C  CA  . LYS   B 2 265 ? 136.686 187.380 188.457 1.00 75.47  ? 1026 LYS   R CA  1 
ATOM   2747 C  C   . LYS   B 2 265 ? 136.045 186.510 189.532 1.00 75.47  ? 1026 LYS   R C   1 
ATOM   2748 O  O   . LYS   B 2 265 ? 134.829 186.285 189.506 1.00 75.47  ? 1026 LYS   R O   1 
ATOM   2749 C  CB  . LYS   B 2 265 ? 137.102 186.536 187.251 1.00 75.47  ? 1026 LYS   R CB  1 
ATOM   2750 C  CG  . LYS   B 2 265 ? 135.966 185.841 186.521 1.00 75.47  ? 1026 LYS   R CG  1 
ATOM   2751 C  CD  . LYS   B 2 265 ? 136.484 185.070 185.317 1.00 75.47  ? 1026 LYS   R CD  1 
ATOM   2752 C  CE  . LYS   B 2 265 ? 135.346 184.436 184.535 1.00 75.47  ? 1026 LYS   R CE  1 
ATOM   2753 N  NZ  . LYS   B 2 265 ? 134.680 183.353 185.307 1.00 75.47  ? 1026 LYS   R NZ  1 
ATOM   2754 N  N   . PHE   B 2 266 ? 136.836 186.030 190.491 1.00 71.44  ? 1027 PHE   R N   1 
ATOM   2755 C  CA  . PHE   B 2 266 ? 136.335 185.228 191.598 1.00 71.44  ? 1027 PHE   R CA  1 
ATOM   2756 C  C   . PHE   B 2 266 ? 136.047 186.060 192.841 1.00 71.44  ? 1027 PHE   R C   1 
ATOM   2757 O  O   . PHE   B 2 266 ? 135.731 185.495 193.892 1.00 71.44  ? 1027 PHE   R O   1 
ATOM   2758 C  CB  . PHE   B 2 266 ? 137.328 184.114 191.933 1.00 71.44  ? 1027 PHE   R CB  1 
ATOM   2759 C  CG  . PHE   B 2 266 ? 137.382 183.022 190.906 1.00 71.44  ? 1027 PHE   R CG  1 
ATOM   2760 C  CD1 . PHE   B 2 266 ? 136.318 182.810 190.041 1.00 71.44  ? 1027 PHE   R CD1 1 
ATOM   2761 C  CD2 . PHE   B 2 266 ? 138.497 182.211 190.800 1.00 71.44  ? 1027 PHE   R CD2 1 
ATOM   2762 C  CE1 . PHE   B 2 266 ? 136.367 181.807 189.092 1.00 71.44  ? 1027 PHE   R CE1 1 
ATOM   2763 C  CE2 . PHE   B 2 266 ? 138.551 181.206 189.855 1.00 71.44  ? 1027 PHE   R CE2 1 
ATOM   2764 C  CZ  . PHE   B 2 266 ? 137.483 181.005 189.000 1.00 71.44  ? 1027 PHE   R CZ  1 
ATOM   2765 N  N   . GLY   B 2 267 ? 136.141 187.382 192.743 1.00 73.27  ? 1028 GLY   R N   1 
ATOM   2766 C  CA  . GLY   B 2 267 ? 135.889 188.251 193.880 1.00 73.27  ? 1028 GLY   R CA  1 
ATOM   2767 C  C   . GLY   B 2 267 ? 136.898 188.135 195.002 1.00 73.27  ? 1028 GLY   R C   1 
ATOM   2768 O  O   . GLY   B 2 267 ? 136.510 188.094 196.176 1.00 73.27  ? 1028 GLY   R O   1 
ATOM   2769 N  N   . MET   B 2 268 ? 138.185 188.081 194.672 1.00 73.39  ? 1029 MET   R N   1 
ATOM   2770 C  CA  . MET   B 2 268 ? 139.239 187.978 195.669 1.00 73.39  ? 1029 MET   R CA  1 
ATOM   2771 C  C   . MET   B 2 268 ? 140.352 188.957 195.329 1.00 73.39  ? 1029 MET   R C   1 
ATOM   2772 O  O   . MET   B 2 268 ? 140.466 189.433 194.197 1.00 73.39  ? 1029 MET   R O   1 
ATOM   2773 C  CB  . MET   B 2 268 ? 139.811 186.559 195.747 1.00 73.39  ? 1029 MET   R CB  1 
ATOM   2774 C  CG  . MET   B 2 268 ? 138.966 185.574 196.525 1.00 73.39  ? 1029 MET   R CG  1 
ATOM   2775 S  SD  . MET   B 2 268 ? 139.657 183.912 196.432 1.00 73.39  ? 1029 MET   R SD  1 
ATOM   2776 C  CE  . MET   B 2 268 ? 138.403 183.078 195.466 1.00 73.39  ? 1029 MET   R CE  1 
ATOM   2777 N  N   . ASP   B 2 269 ? 141.174 189.254 196.329 1.00 76.53  ? 1030 ASP   R N   1 
ATOM   2778 C  CA  . ASP   B 2 269 ? 142.362 190.064 196.121 1.00 76.53  ? 1030 ASP   R CA  1 
ATOM   2779 C  C   . ASP   B 2 269 ? 143.500 189.186 195.604 1.00 76.53  ? 1030 ASP   R C   1 
ATOM   2780 O  O   . ASP   B 2 269 ? 143.362 187.970 195.456 1.00 76.53  ? 1030 ASP   R O   1 
ATOM   2781 C  CB  . ASP   B 2 269 ? 142.752 190.774 197.415 1.00 76.53  ? 1030 ASP   R CB  1 
ATOM   2782 C  CG  . ASP   B 2 269 ? 142.042 192.103 197.586 1.00 76.53  ? 1030 ASP   R CG  1 
ATOM   2783 O  OD1 . ASP   B 2 269 ? 142.505 192.928 198.402 1.00 76.53  ? 1030 ASP   R OD1 1 
ATOM   2784 O  OD2 . ASP   B 2 269 ? 141.019 192.321 196.902 1.00 76.53  ? 1030 ASP   R OD2 1 
ATOM   2785 N  N   . GLU   B 2 270 ? 144.641 189.808 195.320 1.00 76.28  ? 1031 GLU   R N   1 
ATOM   2786 C  CA  . GLU   B 2 270 ? 145.810 189.053 194.896 1.00 76.28  ? 1031 GLU   R CA  1 
ATOM   2787 C  C   . GLU   B 2 270 ? 146.383 188.246 196.056 1.00 76.28  ? 1031 GLU   R C   1 
ATOM   2788 O  O   . GLU   B 2 270 ? 146.114 188.506 197.231 1.00 76.28  ? 1031 GLU   R O   1 
ATOM   2789 C  CB  . GLU   B 2 270 ? 146.892 189.975 194.337 1.00 76.28  ? 1031 GLU   R CB  1 
ATOM   2790 C  CG  . GLU   B 2 270 ? 146.677 190.423 192.902 1.00 76.28  ? 1031 GLU   R CG  1 
ATOM   2791 C  CD  . GLU   B 2 270 ? 147.986 190.540 192.140 1.00 76.28  ? 1031 GLU   R CD  1 
ATOM   2792 O  OE1 . GLU   B 2 270 ? 149.024 190.095 192.671 1.00 76.28  ? 1031 GLU   R OE1 1 
ATOM   2793 O  OE2 . GLU   B 2 270 ? 147.984 191.082 191.017 1.00 76.28  ? 1031 GLU   R OE2 1 
ATOM   2794 N  N   . GLY   B 2 271 ? 147.181 187.252 195.706 1.00 67.73  ? 1032 GLY   R N   1 
ATOM   2795 C  CA  . GLY   B 2 271 ? 147.803 186.402 196.697 1.00 67.73  ? 1032 GLY   R CA  1 
ATOM   2796 C  C   . GLY   B 2 271 ? 148.264 185.111 196.061 1.00 67.73  ? 1032 GLY   R C   1 
ATOM   2797 O  O   . GLY   B 2 271 ? 148.046 184.857 194.876 1.00 67.73  ? 1032 GLY   R O   1 
ATOM   2798 N  N   . VAL   B 2 272 ? 148.911 184.292 196.886 1.00 58.65  ? 1033 VAL   R N   1 
ATOM   2799 C  CA  . VAL   B 2 272 ? 149.404 183.004 196.421 1.00 58.65  ? 1033 VAL   R CA  1 
ATOM   2800 C  C   . VAL   B 2 272 ? 148.214 182.084 196.188 1.00 58.65  ? 1033 VAL   R C   1 
ATOM   2801 O  O   . VAL   B 2 272 ? 147.465 181.764 197.118 1.00 58.65  ? 1033 VAL   R O   1 
ATOM   2802 C  CB  . VAL   B 2 272 ? 150.398 182.407 197.422 1.00 58.65  ? 1033 VAL   R CB  1 
ATOM   2803 C  CG1 . VAL   B 2 272 ? 150.937 181.098 196.907 1.00 58.65  ? 1033 VAL   R CG1 1 
ATOM   2804 C  CG2 . VAL   B 2 272 ? 151.530 183.385 197.656 1.00 58.65  ? 1033 VAL   R CG2 1 
ATOM   2805 N  N   . THR   B 2 273 ? 148.031 181.667 194.940 1.00 55.10  ? 1034 THR   R N   1 
ATOM   2806 C  CA  . THR   B 2 273 ? 146.856 180.922 194.518 1.00 55.10  ? 1034 THR   R CA  1 
ATOM   2807 C  C   . THR   B 2 273 ? 147.184 179.439 194.419 1.00 55.10  ? 1034 THR   R C   1 
ATOM   2808 O  O   . THR   B 2 273 ? 148.287 179.062 194.017 1.00 55.10  ? 1034 THR   R O   1 
ATOM   2809 C  CB  . THR   B 2 273 ? 146.351 181.440 193.171 1.00 55.10  ? 1034 THR   R CB  1 
ATOM   2810 O  OG1 . THR   B 2 273 ? 146.399 182.870 193.168 1.00 55.10  ? 1034 THR   R OG1 1 
ATOM   2811 C  CG2 . THR   B 2 273 ? 144.919 181.002 192.922 1.00 55.10  ? 1034 THR   R CG2 1 
ATOM   2812 N  N   . PHE   B 2 274 ? 146.222 178.603 194.797 1.00 51.44  ? 1035 PHE   R N   1 
ATOM   2813 C  CA  . PHE   B 2 274 ? 146.343 177.160 194.717 1.00 51.44  ? 1035 PHE   R CA  1 
ATOM   2814 C  C   . PHE   B 2 274 ? 145.112 176.605 194.018 1.00 51.44  ? 1035 PHE   R C   1 
ATOM   2815 O  O   . PHE   B 2 274 ? 144.018 177.164 194.124 1.00 51.44  ? 1035 PHE   R O   1 
ATOM   2816 C  CB  . PHE   B 2 274 ? 146.489 176.545 196.107 1.00 51.44  ? 1035 PHE   R CB  1 
ATOM   2817 C  CG  . PHE   B 2 274 ? 147.694 177.029 196.860 1.00 51.44  ? 1035 PHE   R CG  1 
ATOM   2818 C  CD1 . PHE   B 2 274 ? 147.632 178.169 197.639 1.00 51.44  ? 1035 PHE   R CD1 1 
ATOM   2819 C  CD2 . PHE   B 2 274 ? 148.886 176.336 196.799 1.00 51.44  ? 1035 PHE   R CD2 1 
ATOM   2820 C  CE1 . PHE   B 2 274 ? 148.737 178.610 198.331 1.00 51.44  ? 1035 PHE   R CE1 1 
ATOM   2821 C  CE2 . PHE   B 2 274 ? 149.995 176.776 197.489 1.00 51.44  ? 1035 PHE   R CE2 1 
ATOM   2822 C  CZ  . PHE   B 2 274 ? 149.919 177.911 198.257 1.00 51.44  ? 1035 PHE   R CZ  1 
ATOM   2823 N  N   . MET   B 2 275 ? 145.296 175.507 193.292 1.00 53.15  ? 1036 MET   R N   1 
ATOM   2824 C  CA  . MET   B 2 275 ? 144.247 174.959 192.447 1.00 53.15  ? 1036 MET   R CA  1 
ATOM   2825 C  C   . MET   B 2 275 ? 144.137 173.453 192.635 1.00 53.15  ? 1036 MET   R C   1 
ATOM   2826 O  O   . MET   B 2 275 ? 145.136 172.772 192.881 1.00 53.15  ? 1036 MET   R O   1 
ATOM   2827 C  CB  . MET   B 2 275 ? 144.510 175.277 190.971 1.00 53.15  ? 1036 MET   R CB  1 
ATOM   2828 C  CG  . MET   B 2 275 ? 143.302 175.120 190.067 1.00 53.15  ? 1036 MET   R CG  1 
ATOM   2829 S  SD  . MET   B 2 275 ? 143.747 175.185 188.326 1.00 53.15  ? 1036 MET   R SD  1 
ATOM   2830 C  CE  . MET   B 2 275 ? 142.474 174.151 187.620 1.00 53.15  ? 1036 MET   R CE  1 
ATOM   2831 N  N   . PHE   B 2 276 ? 142.912 172.948 192.533 1.00 50.34  ? 1037 PHE   R N   1 
ATOM   2832 C  CA  . PHE   B 2 276 ? 142.643 171.520 192.465 1.00 50.34  ? 1037 PHE   R CA  1 
ATOM   2833 C  C   . PHE   B 2 276 ? 141.583 171.302 191.401 1.00 50.34  ? 1037 PHE   R C   1 
ATOM   2834 O  O   . PHE   B 2 276 ? 140.578 172.015 191.381 1.00 50.34  ? 1037 PHE   R O   1 
ATOM   2835 C  CB  . PHE   B 2 276 ? 142.164 170.977 193.815 1.00 50.34  ? 1037 PHE   R CB  1 
ATOM   2836 C  CG  . PHE   B 2 276 ? 141.678 169.551 193.770 1.00 50.34  ? 1037 PHE   R CG  1 
ATOM   2837 C  CD1 . PHE   B 2 276 ? 142.573 168.501 193.837 1.00 50.34  ? 1037 PHE   R CD1 1 
ATOM   2838 C  CD2 . PHE   B 2 276 ? 140.325 169.262 193.675 1.00 50.34  ? 1037 PHE   R CD2 1 
ATOM   2839 C  CE1 . PHE   B 2 276 ? 142.132 167.197 193.801 1.00 50.34  ? 1037 PHE   R CE1 1 
ATOM   2840 C  CE2 . PHE   B 2 276 ? 139.885 167.959 193.633 1.00 50.34  ? 1037 PHE   R CE2 1 
ATOM   2841 C  CZ  . PHE   B 2 276 ? 140.789 166.927 193.698 1.00 50.34  ? 1037 PHE   R CZ  1 
ATOM   2842 N  N   . ILE   B 2 277 ? 141.804 170.331 190.521 1.00 50.36  ? 1038 ILE   R N   1 
ATOM   2843 C  CA  . ILE   B 2 277 ? 140.789 169.914 189.560 1.00 50.36  ? 1038 ILE   R CA  1 
ATOM   2844 C  C   . ILE   B 2 277 ? 140.781 168.392 189.499 1.00 50.36  ? 1038 ILE   R C   1 
ATOM   2845 O  O   . ILE   B 2 277 ? 141.840 167.757 189.467 1.00 50.36  ? 1038 ILE   R O   1 
ATOM   2846 C  CB  . ILE   B 2 277 ? 141.008 170.549 188.169 1.00 50.36  ? 1038 ILE   R CB  1 
ATOM   2847 C  CG1 . ILE   B 2 277 ? 139.899 170.124 187.203 1.00 50.36  ? 1038 ILE   R CG1 1 
ATOM   2848 C  CG2 . ILE   B 2 277 ? 142.402 170.271 187.628 1.00 50.36  ? 1038 ILE   R CG2 1 
ATOM   2849 C  CD1 . ILE   B 2 277 ? 139.839 170.934 185.942 1.00 50.36  ? 1038 ILE   R CD1 1 
ATOM   2850 N  N   . GLY   B 2 278 ? 139.593 167.806 189.540 1.00 53.76  ? 1039 GLY   R N   1 
ATOM   2851 C  CA  . GLY   B 2 278 ? 139.482 166.363 189.541 1.00 53.76  ? 1039 GLY   R CA  1 
ATOM   2852 C  C   . GLY   B 2 278 ? 138.141 165.924 190.081 1.00 53.76  ? 1039 GLY   R C   1 
ATOM   2853 O  O   . GLY   B 2 278 ? 137.273 166.736 190.408 1.00 53.76  ? 1039 GLY   R O   1 
ATOM   2854 N  N   . ARG   B 2 279 ? 137.995 164.607 190.171 1.00 59.65  ? 1040 ARG   R N   1 
ATOM   2855 C  CA  . ARG   B 2 279 ? 136.748 163.997 190.604 1.00 59.65  ? 1040 ARG   R CA  1 
ATOM   2856 C  C   . ARG   B 2 279 ? 136.544 164.160 192.106 1.00 59.65  ? 1040 ARG   R C   1 
ATOM   2857 O  O   . ARG   B 2 279 ? 137.496 164.160 192.890 1.00 59.65  ? 1040 ARG   R O   1 
ATOM   2858 C  CB  . ARG   B 2 279 ? 136.744 162.515 190.240 1.00 59.65  ? 1040 ARG   R CB  1 
ATOM   2859 C  CG  . ARG   B 2 279 ? 135.383 161.937 189.932 1.00 59.65  ? 1040 ARG   R CG  1 
ATOM   2860 C  CD  . ARG   B 2 279 ? 135.507 160.459 189.620 1.00 59.65  ? 1040 ARG   R CD  1 
ATOM   2861 N  NE  . ARG   B 2 279 ? 136.440 160.222 188.526 1.00 59.65  ? 1040 ARG   R NE  1 
ATOM   2862 C  CZ  . ARG   B 2 279 ? 137.387 159.295 188.537 1.00 59.65  ? 1040 ARG   R CZ  1 
ATOM   2863 N  NH1 . ARG   B 2 279 ? 137.558 158.496 189.575 1.00 59.65  ? 1040 ARG   R NH1 1 
ATOM   2864 N  NH2 . ARG   B 2 279 ? 138.184 159.170 187.480 1.00 59.65  ? 1040 ARG   R NH2 1 
ATOM   2865 N  N   . PHE   B 2 280 ? 135.280 164.291 192.504 1.00 60.31  ? 1041 PHE   R N   1 
ATOM   2866 C  CA  . PHE   B 2 280 ? 134.893 164.370 193.912 1.00 60.31  ? 1041 PHE   R CA  1 
ATOM   2867 C  C   . PHE   B 2 280 ? 134.441 162.983 194.349 1.00 60.31  ? 1041 PHE   R C   1 
ATOM   2868 O  O   . PHE   B 2 280 ? 133.268 162.630 194.237 1.00 60.31  ? 1041 PHE   R O   1 
ATOM   2869 C  CB  . PHE   B 2 280 ? 133.786 165.393 194.124 1.00 60.31  ? 1041 PHE   R CB  1 
ATOM   2870 C  CG  . PHE   B 2 280 ? 134.274 166.757 194.490 1.00 60.31  ? 1041 PHE   R CG  1 
ATOM   2871 C  CD1 . PHE   B 2 280 ? 135.194 167.417 193.700 1.00 60.31  ? 1041 PHE   R CD1 1 
ATOM   2872 C  CD2 . PHE   B 2 280 ? 133.794 167.390 195.618 1.00 60.31  ? 1041 PHE   R CD2 1 
ATOM   2873 C  CE1 . PHE   B 2 280 ? 135.633 168.678 194.039 1.00 60.31  ? 1041 PHE   R CE1 1 
ATOM   2874 C  CE2 . PHE   B 2 280 ? 134.227 168.648 195.957 1.00 60.31  ? 1041 PHE   R CE2 1 
ATOM   2875 C  CZ  . PHE   B 2 280 ? 135.146 169.291 195.168 1.00 60.31  ? 1041 PHE   R CZ  1 
ATOM   2876 N  N   . ASP   B 2 281 ? 135.382 162.192 194.854 1.00 66.20  ? 1042 ASP   R N   1 
ATOM   2877 C  CA  . ASP   B 2 281 ? 135.064 160.864 195.357 1.00 66.20  ? 1042 ASP   R CA  1 
ATOM   2878 C  C   . ASP   B 2 281 ? 136.080 160.464 196.417 1.00 66.20  ? 1042 ASP   R C   1 
ATOM   2879 O  O   . ASP   B 2 281 ? 137.137 161.085 196.555 1.00 66.20  ? 1042 ASP   R O   1 
ATOM   2880 C  CB  . ASP   B 2 281 ? 134.941 159.840 194.206 1.00 66.20  ? 1042 ASP   R CB  1 
ATOM   2881 C  CG  . ASP   B 2 281 ? 136.288 159.326 193.656 1.00 66.20  ? 1042 ASP   R CG  1 
ATOM   2882 O  OD1 . ASP   B 2 281 ? 136.232 158.399 192.822 1.00 66.20  ? 1042 ASP   R OD1 1 
ATOM   2883 O  OD2 . ASP   B 2 281 ? 137.377 159.879 193.922 1.00 66.20  ? 1042 ASP   R OD2 1 
ATOM   2884 N  N   . ARG   B 2 282 ? 135.740 159.425 197.169 1.00 67.82  ? 1043 ARG   R N   1 
ATOM   2885 C  CA  . ARG   B 2 282 ? 136.623 158.881 198.189 1.00 67.82  ? 1043 ARG   R CA  1 
ATOM   2886 C  C   . ARG   B 2 282 ? 137.304 157.636 197.640 1.00 67.82  ? 1043 ARG   R C   1 
ATOM   2887 O  O   . ARG   B 2 282 ? 136.633 156.656 197.298 1.00 67.82  ? 1043 ARG   R O   1 
ATOM   2888 C  CB  . ARG   B 2 282 ? 135.853 158.553 199.466 1.00 67.82  ? 1043 ARG   R CB  1 
ATOM   2889 C  CG  . ARG   B 2 282 ? 135.484 159.768 200.294 1.00 67.82  ? 1043 ARG   R CG  1 
ATOM   2890 C  CD  . ARG   B 2 282 ? 134.761 159.369 201.564 1.00 67.82  ? 1043 ARG   R CD  1 
ATOM   2891 N  NE  . ARG   B 2 282 ? 134.183 160.524 202.238 1.00 67.82  ? 1043 ARG   R NE  1 
ATOM   2892 C  CZ  . ARG   B 2 282 ? 133.002 161.048 201.944 1.00 67.82  ? 1043 ARG   R CZ  1 
ATOM   2893 N  NH1 . ARG   B 2 282 ? 132.236 160.536 200.994 1.00 67.82  ? 1043 ARG   R NH1 1 
ATOM   2894 N  NH2 . ARG   B 2 282 ? 132.579 162.112 202.618 1.00 67.82  ? 1043 ARG   R NH2 1 
ATOM   2895 N  N   . GLY   B 2 283 ? 138.629 157.677 197.556 1.00 68.62  ? 1044 GLY   R N   1 
ATOM   2896 C  CA  . GLY   B 2 283 ? 139.392 156.526 197.124 1.00 68.62  ? 1044 GLY   R CA  1 
ATOM   2897 C  C   . GLY   B 2 283 ? 140.286 156.782 195.930 1.00 68.62  ? 1044 GLY   R C   1 
ATOM   2898 O  O   . GLY   B 2 283 ? 141.420 156.298 195.891 1.00 68.62  ? 1044 GLY   R O   1 
ATOM   2899 N  N   . GLN   B 2 284 ? 139.804 157.548 194.952 1.00 64.94  ? 1045 GLN   R N   1 
ATOM   2900 C  CA  . GLN   B 2 284 ? 140.595 157.817 193.756 1.00 64.94  ? 1045 GLN   R CA  1 
ATOM   2901 C  C   . GLN   B 2 284 ? 141.454 159.067 193.922 1.00 64.94  ? 1045 GLN   R C   1 
ATOM   2902 O  O   . GLN   B 2 284 ? 142.685 158.995 193.864 1.00 64.94  ? 1045 GLN   R O   1 
ATOM   2903 C  CB  . GLN   B 2 284 ? 139.675 157.956 192.540 1.00 64.94  ? 1045 GLN   R CB  1 
ATOM   2904 C  CG  . GLN   B 2 284 ? 139.225 156.636 191.943 1.00 64.94  ? 1045 GLN   R CG  1 
ATOM   2905 C  CD  . GLN   B 2 284 ? 140.287 156.000 191.073 1.00 64.94  ? 1045 GLN   R CD  1 
ATOM   2906 O  OE1 . GLN   B 2 284 ? 140.602 154.822 191.220 1.00 64.94  ? 1045 GLN   R OE1 1 
ATOM   2907 N  NE2 . GLN   B 2 284 ? 140.844 156.781 190.156 1.00 64.94  ? 1045 GLN   R NE2 1 
ATOM   2908 N  N   . LYS   B 2 285 ? 140.819 160.213 194.142 1.00 63.49  ? 1046 LYS   R N   1 
ATOM   2909 C  CA  . LYS   B 2 285 ? 141.511 161.480 194.317 1.00 63.49  ? 1046 LYS   R CA  1 
ATOM   2910 C  C   . LYS   B 2 285 ? 141.228 162.015 195.710 1.00 63.49  ? 1046 LYS   R C   1 
ATOM   2911 O  O   . LYS   B 2 285 ? 140.090 161.965 196.185 1.00 63.49  ? 1046 LYS   R O   1 
ATOM   2912 C  CB  . LYS   B 2 285 ? 141.079 162.505 193.268 1.00 63.49  ? 1046 LYS   R CB  1 
ATOM   2913 C  CG  . LYS   B 2 285 ? 141.726 162.310 191.916 1.00 63.49  ? 1046 LYS   R CG  1 
ATOM   2914 C  CD  . LYS   B 2 285 ? 140.832 161.502 190.998 1.00 63.49  ? 1046 LYS   R CD  1 
ATOM   2915 C  CE  . LYS   B 2 285 ? 141.480 161.297 189.643 1.00 63.49  ? 1046 LYS   R CE  1 
ATOM   2916 N  NZ  . LYS   B 2 285 ? 140.990 160.059 188.981 1.00 63.49  ? 1046 LYS   R NZ  1 
ATOM   2917 N  N   . GLY   B 2 286 ? 142.265 162.528 196.360 1.00 64.00  ? 1047 GLY   R N   1 
ATOM   2918 C  CA  . GLY   B 2 286 ? 142.127 162.991 197.723 1.00 64.00  ? 1047 GLY   R CA  1 
ATOM   2919 C  C   . GLY   B 2 286 ? 141.573 164.392 197.838 1.00 64.00  ? 1047 GLY   R C   1 
ATOM   2920 O  O   . GLY   B 2 286 ? 142.255 165.291 198.336 1.00 64.00  ? 1047 GLY   R O   1 
ATOM   2921 N  N   . VAL   B 2 287 ? 140.339 164.596 197.374 1.00 60.44  ? 1048 VAL   R N   1 
ATOM   2922 C  CA  . VAL   B 2 287 ? 139.688 165.883 197.580 1.00 60.44  ? 1048 VAL   R CA  1 
ATOM   2923 C  C   . VAL   B 2 287 ? 139.400 166.096 199.063 1.00 60.44  ? 1048 VAL   R C   1 
ATOM   2924 O  O   . VAL   B 2 287 ? 139.507 167.220 199.567 1.00 60.44  ? 1048 VAL   R O   1 
ATOM   2925 C  CB  . VAL   B 2 287 ? 138.428 165.992 196.695 1.00 60.44  ? 1048 VAL   R CB  1 
ATOM   2926 C  CG1 . VAL   B 2 287 ? 137.435 164.885 196.990 1.00 60.44  ? 1048 VAL   R CG1 1 
ATOM   2927 C  CG2 . VAL   B 2 287 ? 137.775 167.355 196.835 1.00 60.44  ? 1048 VAL   R CG2 1 
ATOM   2928 N  N   . ASP   B 2 288 ? 139.084 165.023 199.795 1.00 67.47  ? 1049 ASP   R N   1 
ATOM   2929 C  CA  . ASP   B 2 288 ? 138.886 165.136 201.236 1.00 67.47  ? 1049 ASP   R CA  1 
ATOM   2930 C  C   . ASP   B 2 288 ? 140.188 165.445 201.961 1.00 67.47  ? 1049 ASP   R C   1 
ATOM   2931 O  O   . ASP   B 2 288 ? 140.171 166.134 202.986 1.00 67.47  ? 1049 ASP   R O   1 
ATOM   2932 C  CB  . ASP   B 2 288 ? 138.259 163.854 201.782 1.00 67.47  ? 1049 ASP   R CB  1 
ATOM   2933 C  CG  . ASP   B 2 288 ? 138.965 162.610 201.294 1.00 67.47  ? 1049 ASP   R CG  1 
ATOM   2934 O  OD1 . ASP   B 2 288 ? 139.847 162.735 200.423 1.00 67.47  ? 1049 ASP   R OD1 1 
ATOM   2935 O  OD2 . ASP   B 2 288 ? 138.637 161.507 201.779 1.00 67.47  ? 1049 ASP   R OD2 1 
ATOM   2936 N  N   . VAL   B 2 289 ? 141.318 164.960 201.441 1.00 62.79  ? 1050 VAL   R N   1 
ATOM   2937 C  CA  . VAL   B 2 289 ? 142.619 165.333 201.990 1.00 62.79  ? 1050 VAL   R CA  1 
ATOM   2938 C  C   . VAL   B 2 289 ? 142.847 166.829 201.835 1.00 62.79  ? 1050 VAL   R C   1 
ATOM   2939 O  O   . VAL   B 2 289 ? 143.312 167.506 202.762 1.00 62.79  ? 1050 VAL   R O   1 
ATOM   2940 C  CB  . VAL   B 2 289 ? 143.734 164.518 201.311 1.00 62.79  ? 1050 VAL   R CB  1 
ATOM   2941 C  CG1 . VAL   B 2 289 ? 145.098 165.031 201.720 1.00 62.79  ? 1050 VAL   R CG1 1 
ATOM   2942 C  CG2 . VAL   B 2 289 ? 143.596 163.058 201.666 1.00 62.79  ? 1050 VAL   R CG2 1 
ATOM   2943 N  N   . LEU   B 2 290 ? 142.499 167.369 200.667 1.00 58.83  ? 1051 LEU   R N   1 
ATOM   2944 C  CA  . LEU   B 2 290 ? 142.632 168.802 200.437 1.00 58.83  ? 1051 LEU   R CA  1 
ATOM   2945 C  C   . LEU   B 2 290 ? 141.708 169.600 201.347 1.00 58.83  ? 1051 LEU   R C   1 
ATOM   2946 O  O   . LEU   B 2 290 ? 142.098 170.650 201.867 1.00 58.83  ? 1051 LEU   R O   1 
ATOM   2947 C  CB  . LEU   B 2 290 ? 142.348 169.123 198.974 1.00 58.83  ? 1051 LEU   R CB  1 
ATOM   2948 C  CG  . LEU   B 2 290 ? 142.464 170.600 198.619 1.00 58.83  ? 1051 LEU   R CG  1 
ATOM   2949 C  CD1 . LEU   B 2 290 ? 143.909 170.972 198.363 1.00 58.83  ? 1051 LEU   R CD1 1 
ATOM   2950 C  CD2 . LEU   B 2 290 ? 141.603 170.907 197.425 1.00 58.83  ? 1051 LEU   R CD2 1 
ATOM   2951 N  N   . LEU   B 2 291 ? 140.479 169.119 201.553 1.00 58.95  ? 1052 LEU   R N   1 
ATOM   2952 C  CA  . LEU   B 2 291 ? 139.548 169.829 202.426 1.00 58.95  ? 1052 LEU   R CA  1 
ATOM   2953 C  C   . LEU   B 2 291 ? 140.019 169.811 203.877 1.00 58.95  ? 1052 LEU   R C   1 
ATOM   2954 O  O   . LEU   B 2 291 ? 139.909 170.823 204.582 1.00 58.95  ? 1052 LEU   R O   1 
ATOM   2955 C  CB  . LEU   B 2 291 ? 138.151 169.229 202.295 1.00 58.95  ? 1052 LEU   R CB  1 
ATOM   2956 C  CG  . LEU   B 2 291 ? 137.493 169.430 200.929 1.00 58.95  ? 1052 LEU   R CG  1 
ATOM   2957 C  CD1 . LEU   B 2 291 ? 136.122 168.786 200.881 1.00 58.95  ? 1052 LEU   R CD1 1 
ATOM   2958 C  CD2 . LEU   B 2 291 ? 137.402 170.898 200.588 1.00 58.95  ? 1052 LEU   R CD2 1 
ATOM   2959 N  N   . LYS   B 2 292 ? 140.564 168.680 204.334 1.00 63.52  ? 1053 LYS   R N   1 
ATOM   2960 C  CA  . LYS   B 2 292 ? 141.143 168.618 205.673 1.00 63.52  ? 1053 LYS   R CA  1 
ATOM   2961 C  C   . LYS   B 2 292 ? 142.335 169.557 205.806 1.00 63.52  ? 1053 LYS   R C   1 
ATOM   2962 O  O   . LYS   B 2 292 ? 142.503 170.215 206.839 1.00 63.52  ? 1053 LYS   R O   1 
ATOM   2963 C  CB  . LYS   B 2 292 ? 141.560 167.186 206.002 1.00 63.52  ? 1053 LYS   R CB  1 
ATOM   2964 C  CG  . LYS   B 2 292 ? 140.413 166.253 206.325 1.00 63.52  ? 1053 LYS   R CG  1 
ATOM   2965 C  CD  . LYS   B 2 292 ? 140.812 164.808 206.076 1.00 63.52  ? 1053 LYS   R CD  1 
ATOM   2966 C  CE  . LYS   B 2 292 ? 139.924 163.838 206.839 1.00 63.52  ? 1053 LYS   R CE  1 
ATOM   2967 N  NZ  . LYS   B 2 292 ? 138.480 164.173 206.715 1.00 63.52  ? 1053 LYS   R NZ  1 
ATOM   2968 N  N   . ALA   B 2 293 ? 143.173 169.632 204.769 1.00 61.24  ? 1054 ALA   R N   1 
ATOM   2969 C  CA  . ALA   B 2 293 ? 144.309 170.549 204.797 1.00 61.24  ? 1054 ALA   R CA  1 
ATOM   2970 C  C   . ALA   B 2 293 ? 143.855 172.004 204.829 1.00 61.24  ? 1054 ALA   R C   1 
ATOM   2971 O  O   . ALA   B 2 293 ? 144.463 172.832 205.517 1.00 61.24  ? 1054 ALA   R O   1 
ATOM   2972 C  CB  . ALA   B 2 293 ? 145.215 170.297 203.594 1.00 61.24  ? 1054 ALA   R CB  1 
ATOM   2973 N  N   . ILE   B 2 294 ? 142.795 172.334 204.090 1.00 62.97  ? 1055 ILE   R N   1 
ATOM   2974 C  CA  . ILE   B 2 294 ? 142.253 173.690 204.115 1.00 62.97  ? 1055 ILE   R CA  1 
ATOM   2975 C  C   . ILE   B 2 294 ? 141.706 174.020 205.499 1.00 62.97  ? 1055 ILE   R C   1 
ATOM   2976 O  O   . ILE   B 2 294 ? 141.924 175.122 206.018 1.00 62.97  ? 1055 ILE   R O   1 
ATOM   2977 C  CB  . ILE   B 2 294 ? 141.186 173.855 203.018 1.00 62.97  ? 1055 ILE   R CB  1 
ATOM   2978 C  CG1 . ILE   B 2 294 ? 141.846 173.885 201.644 1.00 62.97  ? 1055 ILE   R CG1 1 
ATOM   2979 C  CG2 . ILE   B 2 294 ? 140.371 175.119 203.220 1.00 62.97  ? 1055 ILE   R CG2 1 
ATOM   2980 C  CD1 . ILE   B 2 294 ? 140.861 173.880 200.512 1.00 62.97  ? 1055 ILE   R CD1 1 
ATOM   2981 N  N   . GLU   B 2 295 ? 141.016 173.064 206.130 1.00 65.74  ? 1056 GLU   R N   1 
ATOM   2982 C  CA  . GLU   B 2 295 ? 140.537 173.273 207.494 1.00 65.74  ? 1056 GLU   R CA  1 
ATOM   2983 C  C   . GLU   B 2 295 ? 141.685 173.464 208.478 1.00 65.74  ? 1056 GLU   R C   1 
ATOM   2984 O  O   . GLU   B 2 295 ? 141.571 174.268 209.410 1.00 65.74  ? 1056 GLU   R O   1 
ATOM   2985 C  CB  . GLU   B 2 295 ? 139.666 172.101 207.938 1.00 65.74  ? 1056 GLU   R CB  1 
ATOM   2986 C  CG  . GLU   B 2 295 ? 138.272 172.104 207.356 1.00 65.74  ? 1056 GLU   R CG  1 
ATOM   2987 C  CD  . GLU   B 2 295 ? 137.408 171.008 207.939 1.00 65.74  ? 1056 GLU   R CD  1 
ATOM   2988 O  OE1 . GLU   B 2 295 ? 137.934 170.195 208.728 1.00 65.74  ? 1056 GLU   R OE1 1 
ATOM   2989 O  OE2 . GLU   B 2 295 ? 136.205 170.958 207.608 1.00 65.74  ? 1056 GLU   R OE2 1 
ATOM   2990 N  N   . ILE   B 2 296 ? 142.785 172.733 208.297 1.00 62.68  ? 1057 ILE   R N   1 
ATOM   2991 C  CA  . ILE   B 2 296 ? 143.930 172.875 209.194 1.00 62.68  ? 1057 ILE   R CA  1 
ATOM   2992 C  C   . ILE   B 2 296 ? 144.590 174.240 209.014 1.00 62.68  ? 1057 ILE   R C   1 
ATOM   2993 O  O   . ILE   B 2 296 ? 144.892 174.932 209.993 1.00 62.68  ? 1057 ILE   R O   1 
ATOM   2994 C  CB  . ILE   B 2 296 ? 144.922 171.719 208.976 1.00 62.68  ? 1057 ILE   R CB  1 
ATOM   2995 C  CG1 . ILE   B 2 296 ? 144.347 170.429 209.558 1.00 62.68  ? 1057 ILE   R CG1 1 
ATOM   2996 C  CG2 . ILE   B 2 296 ? 146.268 172.027 209.609 1.00 62.68  ? 1057 ILE   R CG2 1 
ATOM   2997 C  CD1 . ILE   B 2 296 ? 145.275 169.243 209.478 1.00 62.68  ? 1057 ILE   R CD1 1 
ATOM   2998 N  N   . LEU   B 2 297 ? 144.801 174.662 207.763 1.00 67.28  ? 1058 LEU   R N   1 
ATOM   2999 C  CA  . LEU   B 2 297 ? 145.386 175.979 207.513 1.00 67.28  ? 1058 LEU   R CA  1 
ATOM   3000 C  C   . LEU   B 2 297 ? 144.449 177.126 207.862 1.00 67.28  ? 1058 LEU   R C   1 
ATOM   3001 O  O   . LEU   B 2 297 ? 144.918 178.258 208.017 1.00 67.28  ? 1058 LEU   R O   1 
ATOM   3002 C  CB  . LEU   B 2 297 ? 145.832 176.136 206.056 1.00 67.28  ? 1058 LEU   R CB  1 
ATOM   3003 C  CG  . LEU   B 2 297 ? 147.193 175.620 205.575 1.00 67.28  ? 1058 LEU   R CG  1 
ATOM   3004 C  CD1 . LEU   B 2 297 ? 148.309 176.378 206.280 1.00 67.28  ? 1058 LEU   R CD1 1 
ATOM   3005 C  CD2 . LEU   B 2 297 ? 147.380 174.141 205.757 1.00 67.28  ? 1058 LEU   R CD2 1 
ATOM   3006 N  N   . SER   B 2 298 ? 143.143 176.871 207.976 1.00 69.98  ? 1059 SER   R N   1 
ATOM   3007 C  CA  . SER   B 2 298 ? 142.214 177.924 208.368 1.00 69.98  ? 1059 SER   R CA  1 
ATOM   3008 C  C   . SER   B 2 298 ? 142.440 178.402 209.798 1.00 69.98  ? 1059 SER   R C   1 
ATOM   3009 O  O   . SER   B 2 298 ? 142.037 179.520 210.134 1.00 69.98  ? 1059 SER   R O   1 
ATOM   3010 C  CB  . SER   B 2 298 ? 140.776 177.435 208.205 1.00 69.98  ? 1059 SER   R CB  1 
ATOM   3011 O  OG  . SER   B 2 298 ? 139.856 178.389 208.704 1.00 69.98  ? 1059 SER   R OG  1 
ATOM   3012 N  N   . SER   B 2 299 ? 143.077 177.589 210.636 1.00 75.63  ? 1060 SER   R N   1 
ATOM   3013 C  CA  . SER   B 2 299 ? 143.371 177.942 212.016 1.00 75.63  ? 1060 SER   R CA  1 
ATOM   3014 C  C   . SER   B 2 299 ? 144.717 178.635 212.183 1.00 75.63  ? 1060 SER   R C   1 
ATOM   3015 O  O   . SER   B 2 299 ? 145.104 178.934 213.317 1.00 75.63  ? 1060 SER   R O   1 
ATOM   3016 C  CB  . SER   B 2 299 ? 143.335 176.688 212.894 1.00 75.63  ? 1060 SER   R CB  1 
ATOM   3017 O  OG  . SER   B 2 299 ? 142.191 175.900 212.613 1.00 75.63  ? 1060 SER   R OG  1 
ATOM   3018 N  N   . LYS   B 2 300 ? 145.437 178.894 211.098 1.00 76.63  ? 1061 LYS   R N   1 
ATOM   3019 C  CA  . LYS   B 2 300 ? 146.775 179.462 211.164 1.00 76.63  ? 1061 LYS   R CA  1 
ATOM   3020 C  C   . LYS   B 2 300 ? 146.772 180.902 210.667 1.00 76.63  ? 1061 LYS   R C   1 
ATOM   3021 O  O   . LYS   B 2 300 ? 145.796 181.393 210.094 1.00 76.63  ? 1061 LYS   R O   1 
ATOM   3022 C  CB  . LYS   B 2 300 ? 147.764 178.612 210.361 1.00 76.63  ? 1061 LYS   R CB  1 
ATOM   3023 C  CG  . LYS   B 2 300 ? 147.938 177.207 210.915 1.00 76.63  ? 1061 LYS   R CG  1 
ATOM   3024 C  CD  . LYS   B 2 300 ? 149.192 176.544 210.379 1.00 76.63  ? 1061 LYS   R CD  1 
ATOM   3025 C  CE  . LYS   B 2 300 ? 149.503 175.269 211.142 1.00 76.63  ? 1061 LYS   R CE  1 
ATOM   3026 N  NZ  . LYS   B 2 300 ? 148.324 174.363 211.206 1.00 76.63  ? 1061 LYS   R NZ  1 
ATOM   3027 N  N   . LYS   B 2 301 ? 147.897 181.577 210.894 1.00 83.07  ? 1062 LYS   R N   1 
ATOM   3028 C  CA  . LYS   B 2 301 ? 148.018 183.011 210.667 1.00 83.07  ? 1062 LYS   R CA  1 
ATOM   3029 C  C   . LYS   B 2 301 ? 148.442 183.365 209.249 1.00 83.07  ? 1062 LYS   R C   1 
ATOM   3030 O  O   . LYS   B 2 301 ? 148.617 184.551 208.951 1.00 83.07  ? 1062 LYS   R O   1 
ATOM   3031 C  CB  . LYS   B 2 301 ? 149.016 183.615 211.659 1.00 83.07  ? 1062 LYS   R CB  1 
ATOM   3032 C  CG  . LYS   B 2 301 ? 150.454 183.189 211.418 1.00 83.07  ? 1062 LYS   R CG  1 
ATOM   3033 C  CD  . LYS   B 2 301 ? 151.442 184.231 211.926 1.00 83.07  ? 1062 LYS   R CD  1 
ATOM   3034 C  CE  . LYS   B 2 301 ? 151.137 185.613 211.366 1.00 83.07  ? 1062 LYS   R CE  1 
ATOM   3035 N  NZ  . LYS   B 2 301 ? 152.162 186.615 211.766 1.00 83.07  ? 1062 LYS   R NZ  1 
ATOM   3036 N  N   . GLU   B 2 302 ? 148.618 182.379 208.373 1.00 81.00  ? 1063 GLU   R N   1 
ATOM   3037 C  CA  . GLU   B 2 302 ? 149.030 182.627 206.999 1.00 81.00  ? 1063 GLU   R CA  1 
ATOM   3038 C  C   . GLU   B 2 302 ? 147.924 182.337 205.995 1.00 81.00  ? 1063 GLU   R C   1 
ATOM   3039 O  O   . GLU   B 2 302 ? 148.177 182.360 204.787 1.00 81.00  ? 1063 GLU   R O   1 
ATOM   3040 C  CB  . GLU   B 2 302 ? 150.272 181.799 206.667 1.00 81.00  ? 1063 GLU   R CB  1 
ATOM   3041 C  CG  . GLU   B 2 302 ? 151.534 182.270 207.370 1.00 81.00  ? 1063 GLU   R CG  1 
ATOM   3042 C  CD  . GLU   B 2 302 ? 151.744 183.768 207.256 1.00 81.00  ? 1063 GLU   R CD  1 
ATOM   3043 O  OE1 . GLU   B 2 302 ? 152.172 184.229 206.178 1.00 81.00  ? 1063 GLU   R OE1 1 
ATOM   3044 O  OE2 . GLU   B 2 302 ? 151.482 184.485 208.242 1.00 81.00  ? 1063 GLU   R OE2 1 
ATOM   3045 N  N   . PHE   B 2 303 ? 146.703 182.078 206.463 1.00 71.96  ? 1064 PHE   R N   1 
ATOM   3046 C  CA  . PHE   B 2 303 ? 145.593 181.752 205.579 1.00 71.96  ? 1064 PHE   R CA  1 
ATOM   3047 C  C   . PHE   B 2 303 ? 145.104 182.940 204.763 1.00 71.96  ? 1064 PHE   R C   1 
ATOM   3048 O  O   . PHE   B 2 303 ? 144.367 182.740 203.793 1.00 71.96  ? 1064 PHE   R O   1 
ATOM   3049 C  CB  . PHE   B 2 303 ? 144.429 181.181 206.389 1.00 71.96  ? 1064 PHE   R CB  1 
ATOM   3050 C  CG  . PHE   B 2 303 ? 143.475 180.355 205.578 1.00 71.96  ? 1064 PHE   R CG  1 
ATOM   3051 C  CD1 . PHE   B 2 303 ? 143.843 179.107 205.113 1.00 71.96  ? 1064 PHE   R CD1 1 
ATOM   3052 C  CD2 . PHE   B 2 303 ? 142.212 180.831 205.277 1.00 71.96  ? 1064 PHE   R CD2 1 
ATOM   3053 C  CE1 . PHE   B 2 303 ? 142.966 178.346 204.368 1.00 71.96  ? 1064 PHE   R CE1 1 
ATOM   3054 C  CE2 . PHE   B 2 303 ? 141.331 180.075 204.532 1.00 71.96  ? 1064 PHE   R CE2 1 
ATOM   3055 C  CZ  . PHE   B 2 303 ? 141.709 178.833 204.076 1.00 71.96  ? 1064 PHE   R CZ  1 
ATOM   3056 N  N   . GLN   B 2 304 ? 145.482 184.163 205.127 1.00 76.76  ? 1065 GLN   R N   1 
ATOM   3057 C  CA  . GLN   B 2 304 ? 145.094 185.328 204.344 1.00 76.76  ? 1065 GLN   R CA  1 
ATOM   3058 C  C   . GLN   B 2 304 ? 145.887 185.454 203.050 1.00 76.76  ? 1065 GLN   R C   1 
ATOM   3059 O  O   . GLN   B 2 304 ? 145.455 186.176 202.145 1.00 76.76  ? 1065 GLN   R O   1 
ATOM   3060 C  CB  . GLN   B 2 304 ? 145.256 186.609 205.170 1.00 76.76  ? 1065 GLN   R CB  1 
ATOM   3061 C  CG  . GLN   B 2 304 ? 144.877 186.481 206.642 1.00 76.76  ? 1065 GLN   R CG  1 
ATOM   3062 C  CD  . GLN   B 2 304 ? 146.049 186.082 207.519 1.00 76.76  ? 1065 GLN   R CD  1 
ATOM   3063 O  OE1 . GLN   B 2 304 ? 147.199 186.391 207.213 1.00 76.76  ? 1065 GLN   R OE1 1 
ATOM   3064 N  NE2 . GLN   B 2 304 ? 145.760 185.392 208.616 1.00 76.76  ? 1065 GLN   R NE2 1 
ATOM   3065 N  N   . GLU   B 2 305 ? 147.024 184.769 202.940 1.00 71.73  ? 1066 GLU   R N   1 
ATOM   3066 C  CA  . GLU   B 2 305 ? 147.859 184.802 201.748 1.00 71.73  ? 1066 GLU   R CA  1 
ATOM   3067 C  C   . GLU   B 2 305 ? 147.762 183.509 200.946 1.00 71.73  ? 1066 GLU   R C   1 
ATOM   3068 O  O   . GLU   B 2 305 ? 148.714 183.140 200.254 1.00 71.73  ? 1066 GLU   R O   1 
ATOM   3069 C  CB  . GLU   B 2 305 ? 149.312 185.076 202.131 1.00 71.73  ? 1066 GLU   R CB  1 
ATOM   3070 C  CG  . GLU   B 2 305 ? 149.603 186.519 202.489 1.00 71.73  ? 1066 GLU   R CG  1 
ATOM   3071 C  CD  . GLU   B 2 305 ? 151.068 186.752 202.799 1.00 71.73  ? 1066 GLU   R CD  1 
ATOM   3072 O  OE1 . GLU   B 2 305 ? 151.824 185.761 202.871 1.00 71.73  ? 1066 GLU   R OE1 1 
ATOM   3073 O  OE2 . GLU   B 2 305 ? 151.464 187.924 202.973 1.00 71.73  ? 1066 GLU   R OE2 1 
ATOM   3074 N  N   . MET   B 2 306 ? 146.636 182.804 201.038 1.00 64.23  ? 1067 MET   R N   1 
ATOM   3075 C  CA  . MET   B 2 306 ? 146.473 181.487 200.418 1.00 64.23  ? 1067 MET   R CA  1 
ATOM   3076 C  C   . MET   B 2 306 ? 145.065 181.408 199.839 1.00 64.23  ? 1067 MET   R C   1 
ATOM   3077 O  O   . MET   B 2 306 ? 144.120 181.069 200.555 1.00 64.23  ? 1067 MET   R O   1 
ATOM   3078 C  CB  . MET   B 2 306 ? 146.703 180.374 201.434 1.00 64.23  ? 1067 MET   R CB  1 
ATOM   3079 C  CG  . MET   B 2 306 ? 148.120 180.259 201.956 1.00 64.23  ? 1067 MET   R CG  1 
ATOM   3080 S  SD  . MET   B 2 306 ? 148.275 178.983 203.210 1.00 64.23  ? 1067 MET   R SD  1 
ATOM   3081 C  CE  . MET   B 2 306 ? 148.073 177.520 202.215 1.00 64.23  ? 1067 MET   R CE  1 
ATOM   3082 N  N   . ARG   B 2 307 ? 144.922 181.711 198.555 1.00 62.50  ? 1068 ARG   R N   1 
ATOM   3083 C  CA  . ARG   B 2 307 ? 143.640 181.538 197.891 1.00 62.50  ? 1068 ARG   R CA  1 
ATOM   3084 C  C   . ARG   B 2 307 ? 143.542 180.130 197.321 1.00 62.50  ? 1068 ARG   R C   1 
ATOM   3085 O  O   . ARG   B 2 307 ? 144.547 179.524 196.950 1.00 62.50  ? 1068 ARG   R O   1 
ATOM   3086 C  CB  . ARG   B 2 307 ? 143.459 182.568 196.780 1.00 62.50  ? 1068 ARG   R CB  1 
ATOM   3087 C  CG  . ARG   B 2 307 ? 144.015 183.929 197.124 1.00 62.50  ? 1068 ARG   R CG  1 
ATOM   3088 C  CD  . ARG   B 2 307 ? 143.160 184.626 198.163 1.00 62.50  ? 1068 ARG   R CD  1 
ATOM   3089 N  NE  . ARG   B 2 307 ? 143.535 186.025 198.316 1.00 62.50  ? 1068 ARG   R NE  1 
ATOM   3090 C  CZ  . ARG   B 2 307 ? 144.520 186.451 199.093 1.00 62.50  ? 1068 ARG   R CZ  1 
ATOM   3091 N  NH1 . ARG   B 2 307 ? 145.240 185.612 199.816 1.00 62.50  ? 1068 ARG   R NH1 1 
ATOM   3092 N  NH2 . ARG   B 2 307 ? 144.789 187.751 199.146 1.00 62.50  ? 1068 ARG   R NH2 1 
ATOM   3093 N  N   . PHE   B 2 308 ? 142.318 179.609 197.251 1.00 54.05  ? 1069 PHE   R N   1 
ATOM   3094 C  CA  . PHE   B 2 308 ? 142.088 178.234 196.829 1.00 54.05  ? 1069 PHE   R CA  1 
ATOM   3095 C  C   . PHE   B 2 308 ? 140.960 178.172 195.812 1.00 54.05  ? 1069 PHE   R C   1 
ATOM   3096 O  O   . PHE   B 2 308 ? 139.906 178.783 196.011 1.00 54.05  ? 1069 PHE   R O   1 
ATOM   3097 C  CB  . PHE   B 2 308 ? 141.749 177.344 198.024 1.00 54.05  ? 1069 PHE   R CB  1 
ATOM   3098 C  CG  . PHE   B 2 308 ? 142.921 177.029 198.895 1.00 54.05  ? 1069 PHE   R CG  1 
ATOM   3099 C  CD1 . PHE   B 2 308 ? 143.313 177.900 199.893 1.00 54.05  ? 1069 PHE   R CD1 1 
ATOM   3100 C  CD2 . PHE   B 2 308 ? 143.630 175.856 198.720 1.00 54.05  ? 1069 PHE   R CD2 1 
ATOM   3101 C  CE1 . PHE   B 2 308 ? 144.393 177.609 200.698 1.00 54.05  ? 1069 PHE   R CE1 1 
ATOM   3102 C  CE2 . PHE   B 2 308 ? 144.710 175.560 199.523 1.00 54.05  ? 1069 PHE   R CE2 1 
ATOM   3103 C  CZ  . PHE   B 2 308 ? 145.090 176.436 200.512 1.00 54.05  ? 1069 PHE   R CZ  1 
ATOM   3104 N  N   . ILE   B 2 309 ? 141.184 177.430 194.730 1.00 53.48  ? 1070 ILE   R N   1 
ATOM   3105 C  CA  . ILE   B 2 309 ? 140.160 177.122 193.740 1.00 53.48  ? 1070 ILE   R CA  1 
ATOM   3106 C  C   . ILE   B 2 309 ? 140.026 175.609 193.668 1.00 53.48  ? 1070 ILE   R C   1 
ATOM   3107 O  O   . ILE   B 2 309 ? 141.032 174.901 193.554 1.00 53.48  ? 1070 ILE   R O   1 
ATOM   3108 C  CB  . ILE   B 2 309 ? 140.504 177.699 192.355 1.00 53.48  ? 1070 ILE   R CB  1 
ATOM   3109 C  CG1 . ILE   B 2 309 ? 141.116 179.093 192.484 1.00 53.48  ? 1070 ILE   R CG1 1 
ATOM   3110 C  CG2 . ILE   B 2 309 ? 139.270 177.730 191.470 1.00 53.48  ? 1070 ILE   R CG2 1 
ATOM   3111 C  CD1 . ILE   B 2 309 ? 141.600 179.666 191.181 1.00 53.48  ? 1070 ILE   R CD1 1 
ATOM   3112 N  N   . ILE   B 2 310 ? 138.795 175.111 193.758 1.00 52.24  ? 1071 ILE   R N   1 
ATOM   3113 C  CA  . ILE   B 2 310 ? 138.525 173.677 193.740 1.00 52.24  ? 1071 ILE   R CA  1 
ATOM   3114 C  C   . ILE   B 2 310 ? 137.445 173.405 192.706 1.00 52.24  ? 1071 ILE   R C   1 
ATOM   3115 O  O   . ILE   B 2 310 ? 136.322 173.901 192.839 1.00 52.24  ? 1071 ILE   R O   1 
ATOM   3116 C  CB  . ILE   B 2 310 ? 138.088 173.152 195.116 1.00 52.24  ? 1071 ILE   R CB  1 
ATOM   3117 C  CG1 . ILE   B 2 310 ? 139.181 173.378 196.156 1.00 52.24  ? 1071 ILE   R CG1 1 
ATOM   3118 C  CG2 . ILE   B 2 310 ? 137.760 171.689 195.034 1.00 52.24  ? 1071 ILE   R CG2 1 
ATOM   3119 C  CD1 . ILE   B 2 310 ? 138.649 173.557 197.548 1.00 52.24  ? 1071 ILE   R CD1 1 
ATOM   3120 N  N   . ILE   B 2 311 ? 137.765 172.594 191.702 1.00 53.73  ? 1072 ILE   R N   1 
ATOM   3121 C  CA  . ILE   B 2 311 ? 136.855 172.288 190.606 1.00 53.73  ? 1072 ILE   R CA  1 
ATOM   3122 C  C   . ILE   B 2 311 ? 136.570 170.795 190.619 1.00 53.73  ? 1072 ILE   R C   1 
ATOM   3123 O  O   . ILE   B 2 311 ? 137.494 169.984 190.740 1.00 53.73  ? 1072 ILE   R O   1 
ATOM   3124 C  CB  . ILE   B 2 311 ? 137.441 172.716 189.250 1.00 53.73  ? 1072 ILE   R CB  1 
ATOM   3125 C  CG1 . ILE   B 2 311 ? 137.960 174.151 189.325 1.00 53.73  ? 1072 ILE   R CG1 1 
ATOM   3126 C  CG2 . ILE   B 2 311 ? 136.398 172.588 188.160 1.00 53.73  ? 1072 ILE   R CG2 1 
ATOM   3127 C  CD1 . ILE   B 2 311 ? 138.762 174.566 188.127 1.00 53.73  ? 1072 ILE   R CD1 1 
ATOM   3128 N  N   . GLY   B 2 312 ? 135.300 170.435 190.506 1.00 59.38  ? 1073 GLY   R N   1 
ATOM   3129 C  CA  . GLY   B 2 312 ? 134.930 169.037 190.437 1.00 59.38  ? 1073 GLY   R CA  1 
ATOM   3130 C  C   . GLY   B 2 312 ? 133.505 168.816 190.880 1.00 59.38  ? 1073 GLY   R C   1 
ATOM   3131 O  O   . GLY   B 2 312 ? 132.840 169.708 191.405 1.00 59.38  ? 1073 GLY   R O   1 
ATOM   3132 N  N   . LYS   B 2 313 ? 133.042 167.589 190.652 1.00 63.07  ? 1074 LYS   R N   1 
ATOM   3133 C  CA  . LYS   B 2 313 ? 131.705 167.172 191.044 1.00 63.07  ? 1074 LYS   R CA  1 
ATOM   3134 C  C   . LYS   B 2 313 ? 131.734 165.688 191.369 1.00 63.07  ? 1074 LYS   R C   1 
ATOM   3135 O  O   . LYS   B 2 313 ? 132.626 164.956 190.935 1.00 63.07  ? 1074 LYS   R O   1 
ATOM   3136 C  CB  . LYS   B 2 313 ? 130.674 167.462 189.947 1.00 63.07  ? 1074 LYS   R CB  1 
ATOM   3137 C  CG  . LYS   B 2 313 ? 130.908 166.689 188.662 1.00 63.07  ? 1074 LYS   R CG  1 
ATOM   3138 C  CD  . LYS   B 2 313 ? 129.659 166.639 187.799 1.00 63.07  ? 1074 LYS   R CD  1 
ATOM   3139 C  CE  . LYS   B 2 313 ? 128.473 166.089 188.571 1.00 63.07  ? 1074 LYS   R CE  1 
ATOM   3140 N  NZ  . LYS   B 2 313 ? 127.455 165.489 187.666 1.00 63.07  ? 1074 LYS   R NZ  1 
ATOM   3141 N  N   . GLY   B 2 314 ? 130.750 165.249 192.149 1.00 63.94  ? 1075 GLY   R N   1 
ATOM   3142 C  CA  . GLY   B 2 314 ? 130.709 163.864 192.574 1.00 63.94  ? 1075 GLY   R CA  1 
ATOM   3143 C  C   . GLY   B 2 314 ? 129.672 163.575 193.639 1.00 63.94  ? 1075 GLY   R C   1 
ATOM   3144 O  O   . GLY   B 2 314 ? 128.502 163.938 193.487 1.00 63.94  ? 1075 GLY   R O   1 
ATOM   3145 N  N   . ASP   B 2 315 ? 130.091 162.907 194.715 1.00 66.51  ? 1076 ASP   R N   1 
ATOM   3146 C  CA  . ASP   B 2 315 ? 129.170 162.533 195.775 1.00 66.51  ? 1076 ASP   R CA  1 
ATOM   3147 C  C   . ASP   B 2 315 ? 128.685 163.773 196.526 1.00 66.51  ? 1076 ASP   R C   1 
ATOM   3148 O  O   . ASP   B 2 315 ? 129.425 164.750 196.670 1.00 66.51  ? 1076 ASP   R O   1 
ATOM   3149 C  CB  . ASP   B 2 315 ? 129.836 161.557 196.743 1.00 66.51  ? 1076 ASP   R CB  1 
ATOM   3150 C  CG  . ASP   B 2 315 ? 131.203 162.023 197.196 1.00 66.51  ? 1076 ASP   R CG  1 
ATOM   3151 O  OD1 . ASP   B 2 315 ? 131.723 163.003 196.627 1.00 66.51  ? 1076 ASP   R OD1 1 
ATOM   3152 O  OD2 . ASP   B 2 315 ? 131.760 161.403 198.125 1.00 66.51  ? 1076 ASP   R OD2 1 
ATOM   3153 N  N   . PRO   B 2 316 ? 127.430 163.768 196.992 1.00 69.34  ? 1077 PRO   R N   1 
ATOM   3154 C  CA  . PRO   B 2 316 ? 126.873 164.978 197.619 1.00 69.34  ? 1077 PRO   R CA  1 
ATOM   3155 C  C   . PRO   B 2 316 ? 127.506 165.353 198.949 1.00 69.34  ? 1077 PRO   R C   1 
ATOM   3156 O  O   . PRO   B 2 316 ? 127.438 166.528 199.325 1.00 69.34  ? 1077 PRO   R O   1 
ATOM   3157 C  CB  . PRO   B 2 316 ? 125.388 164.631 197.792 1.00 69.34  ? 1077 PRO   R CB  1 
ATOM   3158 C  CG  . PRO   B 2 316 ? 125.136 163.520 196.830 1.00 69.34  ? 1077 PRO   R CG  1 
ATOM   3159 C  CD  . PRO   B 2 316 ? 126.402 162.734 196.793 1.00 69.34  ? 1077 PRO   R CD  1 
ATOM   3160 N  N   . GLU   B 2 317 ? 128.116 164.412 199.674 1.00 71.24  ? 1078 GLU   R N   1 
ATOM   3161 C  CA  . GLU   B 2 317 ? 128.683 164.750 200.977 1.00 71.24  ? 1078 GLU   R CA  1 
ATOM   3162 C  C   . GLU   B 2 317 ? 129.958 165.574 200.831 1.00 71.24  ? 1078 GLU   R C   1 
ATOM   3163 O  O   . GLU   B 2 317 ? 130.143 166.582 201.525 1.00 71.24  ? 1078 GLU   R O   1 
ATOM   3164 C  CB  . GLU   B 2 317 ? 128.949 163.480 201.781 1.00 71.24  ? 1078 GLU   R CB  1 
ATOM   3165 C  CG  . GLU   B 2 317 ? 129.465 163.746 203.184 1.00 71.24  ? 1078 GLU   R CG  1 
ATOM   3166 C  CD  . GLU   B 2 317 ? 129.672 162.476 203.982 1.00 71.24  ? 1078 GLU   R CD  1 
ATOM   3167 O  OE1 . GLU   B 2 317 ? 129.432 161.381 203.432 1.00 71.24  ? 1078 GLU   R OE1 1 
ATOM   3168 O  OE2 . GLU   B 2 317 ? 130.069 162.573 205.163 1.00 71.24  ? 1078 GLU   R OE2 1 
ATOM   3169 N  N   . LEU   B 2 318 ? 130.849 165.166 199.925 1.00 65.69  ? 1079 LEU   R N   1 
ATOM   3170 C  CA  . LEU   B 2 318 ? 132.060 165.942 199.683 1.00 65.69  ? 1079 LEU   R CA  1 
ATOM   3171 C  C   . LEU   B 2 318 ? 131.744 167.268 199.008 1.00 65.69  ? 1079 LEU   R C   1 
ATOM   3172 O  O   . LEU   B 2 318 ? 132.403 168.277 199.289 1.00 65.69  ? 1079 LEU   R O   1 
ATOM   3173 C  CB  . LEU   B 2 318 ? 133.044 165.132 198.845 1.00 65.69  ? 1079 LEU   R CB  1 
ATOM   3174 C  CG  . LEU   B 2 318 ? 133.900 164.149 199.642 1.00 65.69  ? 1079 LEU   R CG  1 
ATOM   3175 C  CD1 . LEU   B 2 318 ? 134.563 163.146 198.720 1.00 65.69  ? 1079 LEU   R CD1 1 
ATOM   3176 C  CD2 . LEU   B 2 318 ? 134.936 164.892 200.463 1.00 65.69  ? 1079 LEU   R CD2 1 
ATOM   3177 N  N   . GLU   B 2 319 ? 130.735 167.286 198.134 1.00 66.60  ? 1080 GLU   R N   1 
ATOM   3178 C  CA  . GLU   B 2 319 ? 130.264 168.542 197.562 1.00 66.60  ? 1080 GLU   R CA  1 
ATOM   3179 C  C   . GLU   B 2 319 ? 129.737 169.475 198.644 1.00 66.60  ? 1080 GLU   R C   1 
ATOM   3180 O  O   . GLU   B 2 319 ? 130.012 170.679 198.622 1.00 66.60  ? 1080 GLU   R O   1 
ATOM   3181 C  CB  . GLU   B 2 319 ? 129.179 168.268 196.522 1.00 66.60  ? 1080 GLU   R CB  1 
ATOM   3182 C  CG  . GLU   B 2 319 ? 129.695 168.082 195.111 1.00 66.60  ? 1080 GLU   R CG  1 
ATOM   3183 C  CD  . GLU   B 2 319 ? 128.584 167.792 194.125 1.00 66.60  ? 1080 GLU   R CD  1 
ATOM   3184 O  OE1 . GLU   B 2 319 ? 127.545 168.481 194.180 1.00 66.60  ? 1080 GLU   R OE1 1 
ATOM   3185 O  OE2 . GLU   B 2 319 ? 128.747 166.874 193.296 1.00 66.60  ? 1080 GLU   R OE2 1 
ATOM   3186 N  N   . GLY   B 2 320 ? 128.990 168.931 199.607 1.00 66.81  ? 1081 GLY   R N   1 
ATOM   3187 C  CA  . GLY   B 2 320 ? 128.479 169.750 200.693 1.00 66.81  ? 1081 GLY   R CA  1 
ATOM   3188 C  C   . GLY   B 2 320 ? 129.575 170.280 201.594 1.00 66.81  ? 1081 GLY   R C   1 
ATOM   3189 O  O   . GLY   B 2 320 ? 129.512 171.424 202.048 1.00 66.81  ? 1081 GLY   R O   1 
ATOM   3190 N  N   . TRP   B 2 321 ? 130.590 169.458 201.866 1.00 62.11  ? 1082 TRP   R N   1 
ATOM   3191 C  CA  . TRP   B 2 321 ? 131.735 169.916 202.649 1.00 62.11  ? 1082 TRP   R CA  1 
ATOM   3192 C  C   . TRP   B 2 321 ? 132.488 171.032 201.929 1.00 62.11  ? 1082 TRP   R C   1 
ATOM   3193 O  O   . TRP   B 2 321 ? 132.879 172.034 202.549 1.00 62.11  ? 1082 TRP   R O   1 
ATOM   3194 C  CB  . TRP   B 2 321 ? 132.656 168.733 202.941 1.00 62.11  ? 1082 TRP   R CB  1 
ATOM   3195 C  CG  . TRP   B 2 321 ? 133.706 168.980 203.973 1.00 62.11  ? 1082 TRP   R CG  1 
ATOM   3196 C  CD1 . TRP   B 2 321 ? 133.863 170.093 204.743 1.00 62.11  ? 1082 TRP   R CD1 1 
ATOM   3197 C  CD2 . TRP   B 2 321 ? 134.749 168.080 204.354 1.00 62.11  ? 1082 TRP   R CD2 1 
ATOM   3198 N  NE1 . TRP   B 2 321 ? 134.945 169.947 205.573 1.00 62.11  ? 1082 TRP   R NE1 1 
ATOM   3199 C  CE2 . TRP   B 2 321 ? 135.505 168.717 205.355 1.00 62.11  ? 1082 TRP   R CE2 1 
ATOM   3200 C  CE3 . TRP   B 2 321 ? 135.118 166.797 203.944 1.00 62.11  ? 1082 TRP   R CE3 1 
ATOM   3201 C  CZ2 . TRP   B 2 321 ? 136.608 168.115 205.952 1.00 62.11  ? 1082 TRP   R CZ2 1 
ATOM   3202 C  CZ3 . TRP   B 2 321 ? 136.212 166.202 204.536 1.00 62.11  ? 1082 TRP   R CZ3 1 
ATOM   3203 C  CH2 . TRP   B 2 321 ? 136.945 166.860 205.529 1.00 62.11  ? 1082 TRP   R CH2 1 
ATOM   3204 N  N   . ALA   B 2 322 ? 132.685 170.884 200.614 1.00 66.28  ? 1083 ALA   R N   1 
ATOM   3205 C  CA  . ALA   B 2 322 ? 133.352 171.926 199.840 1.00 66.28  ? 1083 ALA   R CA  1 
ATOM   3206 C  C   . ALA   B 2 322 ? 132.532 173.210 199.811 1.00 66.28  ? 1083 ALA   R C   1 
ATOM   3207 O  O   . ALA   B 2 322 ? 133.086 174.308 199.923 1.00 66.28  ? 1083 ALA   R O   1 
ATOM   3208 C  CB  . ALA   B 2 322 ? 133.627 171.429 198.421 1.00 66.28  ? 1083 ALA   R CB  1 
ATOM   3209 N  N   . ARG   B 2 323 ? 131.206 173.095 199.685 1.00 69.27  ? 1084 ARG   R N   1 
ATOM   3210 C  CA  . ARG   B 2 323 ? 130.357 174.284 199.689 1.00 69.27  ? 1084 ARG   R CA  1 
ATOM   3211 C  C   . ARG   B 2 323 ? 130.335 174.950 201.063 1.00 69.27  ? 1084 ARG   R C   1 
ATOM   3212 O  O   . ARG   B 2 323 ? 130.259 176.181 201.162 1.00 69.27  ? 1084 ARG   R O   1 
ATOM   3213 C  CB  . ARG   B 2 323 ? 128.940 173.920 199.246 1.00 69.27  ? 1084 ARG   R CB  1 
ATOM   3214 C  CG  . ARG   B 2 323 ? 128.813 173.558 197.775 1.00 69.27  ? 1084 ARG   R CG  1 
ATOM   3215 C  CD  . ARG   B 2 323 ? 128.893 174.777 196.879 1.00 69.27  ? 1084 ARG   R CD  1 
ATOM   3216 N  NE  . ARG   B 2 323 ? 128.522 174.461 195.505 1.00 69.27  ? 1084 ARG   R NE  1 
ATOM   3217 C  CZ  . ARG   B 2 323 ? 128.920 175.151 194.445 1.00 69.27  ? 1084 ARG   R CZ  1 
ATOM   3218 N  NH1 . ARG   B 2 323 ? 129.705 176.209 194.565 1.00 69.27  ? 1084 ARG   R NH1 1 
ATOM   3219 N  NH2 . ARG   B 2 323 ? 128.520 174.771 193.236 1.00 69.27  ? 1084 ARG   R NH2 1 
ATOM   3220 N  N   . SER   B 2 324 ? 130.396 174.152 202.133 1.00 69.89  ? 1085 SER   R N   1 
ATOM   3221 C  CA  . SER   B 2 324 ? 130.438 174.713 203.479 1.00 69.89  ? 1085 SER   R CA  1 
ATOM   3222 C  C   . SER   B 2 324 ? 131.736 175.471 203.720 1.00 69.89  ? 1085 SER   R C   1 
ATOM   3223 O  O   . SER   B 2 324 ? 131.727 176.536 204.347 1.00 69.89  ? 1085 SER   R O   1 
ATOM   3224 C  CB  . SER   B 2 324 ? 130.263 173.608 204.518 1.00 69.89  ? 1085 SER   R CB  1 
ATOM   3225 O  OG  . SER   B 2 324 ? 131.452 172.852 204.660 1.00 69.89  ? 1085 SER   R OG  1 
ATOM   3226 N  N   . LEU   B 2 325 ? 132.863 174.942 203.233 1.00 69.11  ? 1086 LEU   R N   1 
ATOM   3227 C  CA  . LEU   B 2 325 ? 134.102 175.715 203.312 1.00 69.11  ? 1086 LEU   R CA  1 
ATOM   3228 C  C   . LEU   B 2 325 ? 134.084 176.914 202.371 1.00 69.11  ? 1086 LEU   R C   1 
ATOM   3229 O  O   . LEU   B 2 325 ? 134.773 177.907 202.629 1.00 69.11  ? 1086 LEU   R O   1 
ATOM   3230 C  CB  . LEU   B 2 325 ? 135.313 174.833 203.021 1.00 69.11  ? 1086 LEU   R CB  1 
ATOM   3231 C  CG  . LEU   B 2 325 ? 135.687 173.842 204.120 1.00 69.11  ? 1086 LEU   R CG  1 
ATOM   3232 C  CD1 . LEU   B 2 325 ? 136.834 172.960 203.675 1.00 69.11  ? 1086 LEU   R CD1 1 
ATOM   3233 C  CD2 . LEU   B 2 325 ? 136.057 174.594 205.382 1.00 69.11  ? 1086 LEU   R CD2 1 
ATOM   3234 N  N   . GLU   B 2 326 ? 133.316 176.841 201.280 1.00 70.65  ? 1087 GLU   R N   1 
ATOM   3235 C  CA  . GLU   B 2 326 ? 133.191 177.986 200.384 1.00 70.65  ? 1087 GLU   R CA  1 
ATOM   3236 C  C   . GLU   B 2 326 ? 132.419 179.121 201.041 1.00 70.65  ? 1087 GLU   R C   1 
ATOM   3237 O  O   . GLU   B 2 326 ? 132.731 180.297 200.826 1.00 70.65  ? 1087 GLU   R O   1 
ATOM   3238 C  CB  . GLU   B 2 326 ? 132.510 177.566 199.082 1.00 70.65  ? 1087 GLU   R CB  1 
ATOM   3239 C  CG  . GLU   B 2 326 ? 132.589 178.611 197.977 1.00 70.65  ? 1087 GLU   R CG  1 
ATOM   3240 C  CD  . GLU   B 2 326 ? 131.473 178.483 196.954 1.00 70.65  ? 1087 GLU   R CD  1 
ATOM   3241 O  OE1 . GLU   B 2 326 ? 130.554 177.665 197.171 1.00 70.65  ? 1087 GLU   R OE1 1 
ATOM   3242 O  OE2 . GLU   B 2 326 ? 131.517 179.198 195.930 1.00 70.65  ? 1087 GLU   R OE2 1 
ATOM   3243 N  N   . GLU   B 2 327 ? 131.393 178.793 201.826 1.00 74.62  ? 1088 GLU   R N   1 
ATOM   3244 C  CA  . GLU   B 2 327 ? 130.624 179.833 202.502 1.00 74.62  ? 1088 GLU   R CA  1 
ATOM   3245 C  C   . GLU   B 2 327 ? 131.235 180.246 203.836 1.00 74.62  ? 1088 GLU   R C   1 
ATOM   3246 O  O   . GLU   B 2 327 ? 130.930 181.338 204.326 1.00 74.62  ? 1088 GLU   R O   1 
ATOM   3247 C  CB  . GLU   B 2 327 ? 129.175 179.383 202.712 1.00 74.62  ? 1088 GLU   R CB  1 
ATOM   3248 C  CG  . GLU   B 2 327 ? 128.930 178.557 203.962 1.00 74.62  ? 1088 GLU   R CG  1 
ATOM   3249 C  CD  . GLU   B 2 327 ? 127.505 178.049 204.049 1.00 74.62  ? 1088 GLU   R CD  1 
ATOM   3250 O  OE1 . GLU   B 2 327 ? 126.744 178.244 203.079 1.00 74.62  ? 1088 GLU   R OE1 1 
ATOM   3251 O  OE2 . GLU   B 2 327 ? 127.147 177.453 205.087 1.00 74.62  ? 1088 GLU   R OE2 1 
ATOM   3252 N  N   . LYS   B 2 328 ? 132.083 179.407 204.434 1.00 70.55  ? 1089 LYS   R N   1 
ATOM   3253 C  CA  . LYS   B 2 328 ? 132.719 179.769 205.695 1.00 70.55  ? 1089 LYS   R CA  1 
ATOM   3254 C  C   . LYS   B 2 328 ? 133.840 180.780 205.492 1.00 70.55  ? 1089 LYS   R C   1 
ATOM   3255 O  O   . LYS   B 2 328 ? 133.962 181.737 206.264 1.00 70.55  ? 1089 LYS   R O   1 
ATOM   3256 C  CB  . LYS   B 2 328 ? 133.250 178.516 206.389 1.00 70.55  ? 1089 LYS   R CB  1 
ATOM   3257 C  CG  . LYS   B 2 328 ? 133.598 178.714 207.851 1.00 70.55  ? 1089 LYS   R CG  1 
ATOM   3258 C  CD  . LYS   B 2 328 ? 133.582 177.392 208.600 1.00 70.55  ? 1089 LYS   R CD  1 
ATOM   3259 C  CE  . LYS   B 2 328 ? 132.254 176.675 208.426 1.00 70.55  ? 1089 LYS   R CE  1 
ATOM   3260 N  NZ  . LYS   B 2 328 ? 132.236 175.358 209.119 1.00 70.55  ? 1089 LYS   R NZ  1 
ATOM   3261 N  N   . HIS   B 2 329 ? 134.663 180.587 204.465 1.00 67.19  ? 1090 HIS   R N   1 
ATOM   3262 C  CA  . HIS   B 2 329 ? 135.779 181.470 204.165 1.00 67.19  ? 1090 HIS   R CA  1 
ATOM   3263 C  C   . HIS   B 2 329 ? 135.541 182.155 202.829 1.00 67.19  ? 1090 HIS   R C   1 
ATOM   3264 O  O   . HIS   B 2 329 ? 135.000 181.550 201.900 1.00 67.19  ? 1090 HIS   R O   1 
ATOM   3265 C  CB  . HIS   B 2 329 ? 137.101 180.704 204.112 1.00 67.19  ? 1090 HIS   R CB  1 
ATOM   3266 C  CG  . HIS   B 2 329 ? 137.405 179.934 205.357 1.00 67.19  ? 1090 HIS   R CG  1 
ATOM   3267 N  ND1 . HIS   B 2 329 ? 137.109 178.596 205.494 1.00 67.19  ? 1090 HIS   R ND1 1 
ATOM   3268 C  CD2 . HIS   B 2 329 ? 137.993 180.311 206.517 1.00 67.19  ? 1090 HIS   R CD2 1 
ATOM   3269 C  CE1 . HIS   B 2 329 ? 137.494 178.183 206.687 1.00 67.19  ? 1090 HIS   R CE1 1 
ATOM   3270 N  NE2 . HIS   B 2 329 ? 138.033 179.204 207.328 1.00 67.19  ? 1090 HIS   R NE2 1 
ATOM   3271 N  N   . GLY   B 2 330 ? 135.947 183.416 202.732 1.00 66.85  ? 1091 GLY   R N   1 
ATOM   3272 C  CA  . GLY   B 2 330 ? 135.786 184.131 201.483 1.00 66.85  ? 1091 GLY   R CA  1 
ATOM   3273 C  C   . GLY   B 2 330 ? 136.866 183.888 200.455 1.00 66.85  ? 1091 GLY   R C   1 
ATOM   3274 O  O   . GLY   B 2 330 ? 136.693 184.277 199.296 1.00 66.85  ? 1091 GLY   R O   1 
ATOM   3275 N  N   . ASN   B 2 331 ? 137.969 183.250 200.842 1.00 65.40  ? 1092 ASN   R N   1 
ATOM   3276 C  CA  . ASN   B 2 331 ? 139.100 183.042 199.949 1.00 65.40  ? 1092 ASN   R CA  1 
ATOM   3277 C  C   . ASN   B 2 331 ? 139.154 181.633 199.373 1.00 65.40  ? 1092 ASN   R C   1 
ATOM   3278 O  O   . ASN   B 2 331 ? 140.178 181.251 198.800 1.00 65.40  ? 1092 ASN   R O   1 
ATOM   3279 C  CB  . ASN   B 2 331 ? 140.410 183.363 200.671 1.00 65.40  ? 1092 ASN   R CB  1 
ATOM   3280 C  CG  . ASN   B 2 331 ? 140.672 182.443 201.837 1.00 65.40  ? 1092 ASN   R CG  1 
ATOM   3281 O  OD1 . ASN   B 2 331 ? 139.755 181.824 202.373 1.00 65.40  ? 1092 ASN   R OD1 1 
ATOM   3282 N  ND2 . ASN   B 2 331 ? 141.930 182.350 202.244 1.00 65.40  ? 1092 ASN   R ND2 1 
ATOM   3283 N  N   . VAL   B 2 332 ? 138.087 180.854 199.513 1.00 60.03  ? 1093 VAL   R N   1 
ATOM   3284 C  CA  . VAL   B 2 332 ? 138.003 179.511 198.951 1.00 60.03  ? 1093 VAL   R CA  1 
ATOM   3285 C  C   . VAL   B 2 332 ? 136.833 179.486 197.979 1.00 60.03  ? 1093 VAL   R C   1 
ATOM   3286 O  O   . VAL   B 2 332 ? 135.690 179.749 198.372 1.00 60.03  ? 1093 VAL   R O   1 
ATOM   3287 C  CB  . VAL   B 2 332 ? 137.831 178.447 200.046 1.00 60.03  ? 1093 VAL   R CB  1 
ATOM   3288 C  CG1 . VAL   B 2 332 ? 137.456 177.112 199.435 1.00 60.03  ? 1093 VAL   R CG1 1 
ATOM   3289 C  CG2 . VAL   B 2 332 ? 139.099 178.328 200.872 1.00 60.03  ? 1093 VAL   R CG2 1 
ATOM   3290 N  N   . LYS   B 2 333 ? 137.111 179.166 196.718 1.00 60.34  ? 1094 LYS   R N   1 
ATOM   3291 C  CA  . LYS   B 2 333 ? 136.101 179.121 195.670 1.00 60.34  ? 1094 LYS   R CA  1 
ATOM   3292 C  C   . LYS   B 2 333 ? 135.940 177.687 195.192 1.00 60.34  ? 1094 LYS   R C   1 
ATOM   3293 O  O   . LYS   B 2 333 ? 136.935 176.997 194.953 1.00 60.34  ? 1094 LYS   R O   1 
ATOM   3294 C  CB  . LYS   B 2 333 ? 136.486 180.035 194.504 1.00 60.34  ? 1094 LYS   R CB  1 
ATOM   3295 C  CG  . LYS   B 2 333 ? 135.770 179.739 193.199 1.00 60.34  ? 1094 LYS   R CG  1 
ATOM   3296 C  CD  . LYS   B 2 333 ? 134.344 180.257 193.215 1.00 60.34  ? 1094 LYS   R CD  1 
ATOM   3297 C  CE  . LYS   B 2 333 ? 133.850 180.554 191.808 1.00 60.34  ? 1094 LYS   R CE  1 
ATOM   3298 N  NZ  . LYS   B 2 333 ? 132.380 180.360 191.671 1.00 60.34  ? 1094 LYS   R NZ  1 
ATOM   3299 N  N   . VAL   B 2 334 ? 134.694 177.237 195.070 1.00 61.01  ? 1095 VAL   R N   1 
ATOM   3300 C  CA  . VAL   B 2 334 ? 134.377 175.877 194.651 1.00 61.01  ? 1095 VAL   R CA  1 
ATOM   3301 C  C   . VAL   B 2 334 ? 133.462 175.951 193.437 1.00 61.01  ? 1095 VAL   R C   1 
ATOM   3302 O  O   . VAL   B 2 334 ? 132.385 176.556 193.500 1.00 61.01  ? 1095 VAL   R O   1 
ATOM   3303 C  CB  . VAL   B 2 334 ? 133.721 175.072 195.783 1.00 61.01  ? 1095 VAL   R CB  1 
ATOM   3304 C  CG1 . VAL   B 2 334 ? 133.119 173.783 195.247 1.00 61.01  ? 1095 VAL   R CG1 1 
ATOM   3305 C  CG2 . VAL   B 2 334 ? 134.735 174.779 196.875 1.00 61.01  ? 1095 VAL   R CG2 1 
ATOM   3306 N  N   . ILE   B 2 335 ? 133.886 175.331 192.340 1.00 61.60  ? 1096 ILE   R N   1 
ATOM   3307 C  CA  . ILE   B 2 335 ? 133.115 175.261 191.106 1.00 61.60  ? 1096 ILE   R CA  1 
ATOM   3308 C  C   . ILE   B 2 335 ? 132.695 173.815 190.893 1.00 61.60  ? 1096 ILE   R C   1 
ATOM   3309 O  O   . ILE   B 2 335 ? 133.508 172.897 191.050 1.00 61.60  ? 1096 ILE   R O   1 
ATOM   3310 C  CB  . ILE   B 2 335 ? 133.923 175.778 189.904 1.00 61.60  ? 1096 ILE   R CB  1 
ATOM   3311 C  CG1 . ILE   B 2 335 ? 134.685 177.046 190.280 1.00 61.60  ? 1096 ILE   R CG1 1 
ATOM   3312 C  CG2 . ILE   B 2 335 ? 133.009 176.038 188.724 1.00 61.60  ? 1096 ILE   R CG2 1 
ATOM   3313 C  CD1 . ILE   B 2 335 ? 135.710 177.462 189.258 1.00 61.60  ? 1096 ILE   R CD1 1 
ATOM   3314 N  N   . THR   B 2 336 ? 131.429 173.613 190.545 1.00 68.73  ? 1097 THR   R N   1 
ATOM   3315 C  CA  . THR   B 2 336 ? 130.867 172.283 190.345 1.00 68.73  ? 1097 THR   R CA  1 
ATOM   3316 C  C   . THR   B 2 336 ? 130.512 172.004 188.892 1.00 68.73  ? 1097 THR   R C   1 
ATOM   3317 O  O   . THR   B 2 336 ? 130.669 170.871 188.426 1.00 68.73  ? 1097 THR   R O   1 
ATOM   3318 C  CB  . THR   B 2 336 ? 129.623 172.115 191.234 1.00 68.73  ? 1097 THR   R CB  1 
ATOM   3319 O  OG1 . THR   B 2 336 ? 129.999 172.295 192.604 1.00 68.73  ? 1097 THR   R OG1 1 
ATOM   3320 C  CG2 . THR   B 2 336 ? 129.002 170.731 191.094 1.00 68.73  ? 1097 THR   R CG2 1 
ATOM   3321 N  N   . GLU   B 2 337 ? 130.095 173.027 188.151 1.00 75.28  ? 1098 GLU   R N   1 
ATOM   3322 C  CA  . GLU   B 2 337 ? 129.616 172.853 186.789 1.00 75.28  ? 1098 GLU   R CA  1 
ATOM   3323 C  C   . GLU   B 2 337 ? 130.741 172.407 185.856 1.00 75.28  ? 1098 GLU   R C   1 
ATOM   3324 O  O   . GLU   B 2 337 ? 131.929 172.589 186.133 1.00 75.28  ? 1098 GLU   R O   1 
ATOM   3325 C  CB  . GLU   B 2 337 ? 129.001 174.152 186.271 1.00 75.28  ? 1098 GLU   R CB  1 
ATOM   3326 C  CG  . GLU   B 2 337 ? 127.660 174.501 186.895 1.00 75.28  ? 1098 GLU   R CG  1 
ATOM   3327 C  CD  . GLU   B 2 337 ? 127.805 175.314 188.165 1.00 75.28  ? 1098 GLU   R CD  1 
ATOM   3328 O  OE1 . GLU   B 2 337 ? 128.731 176.148 188.233 1.00 75.28  ? 1098 GLU   R OE1 1 
ATOM   3329 O  OE2 . GLU   B 2 337 ? 126.990 175.123 189.093 1.00 75.28  ? 1098 GLU   R OE2 1 
ATOM   3330 N  N   . MET   B 2 338 ? 130.340 171.796 184.744 1.00 78.71  ? 1099 MET   R N   1 
ATOM   3331 C  CA  . MET   B 2 338 ? 131.291 171.324 183.748 1.00 78.71  ? 1099 MET   R CA  1 
ATOM   3332 C  C   . MET   B 2 338 ? 131.965 172.500 183.053 1.00 78.71  ? 1099 MET   R C   1 
ATOM   3333 O  O   . MET   B 2 338 ? 131.316 173.486 182.696 1.00 78.71  ? 1099 MET   R O   1 
ATOM   3334 C  CB  . MET   B 2 338 ? 130.582 170.443 182.722 1.00 78.71  ? 1099 MET   R CB  1 
ATOM   3335 C  CG  . MET   B 2 338 ? 131.517 169.686 181.806 1.00 78.71  ? 1099 MET   R CG  1 
ATOM   3336 S  SD  . MET   B 2 338 ? 132.067 168.133 182.531 1.00 78.71  ? 1099 MET   R SD  1 
ATOM   3337 C  CE  . MET   B 2 338 ? 133.650 167.943 181.723 1.00 78.71  ? 1099 MET   R CE  1 
ATOM   3338 N  N   . LEU   B 2 339 ? 133.274 172.388 182.854 1.00 72.37  ? 1100 LEU   R N   1 
ATOM   3339 C  CA  . LEU   B 2 339 ? 134.072 173.470 182.302 1.00 72.37  ? 1100 LEU   R CA  1 
ATOM   3340 C  C   . LEU   B 2 339 ? 134.632 173.091 180.938 1.00 72.37  ? 1100 LEU   R C   1 
ATOM   3341 O  O   . LEU   B 2 339 ? 134.770 171.914 180.597 1.00 72.37  ? 1100 LEU   R O   1 
ATOM   3342 C  CB  . LEU   B 2 339 ? 135.221 173.841 183.244 1.00 72.37  ? 1100 LEU   R CB  1 
ATOM   3343 C  CG  . LEU   B 2 339 ? 134.853 174.301 184.654 1.00 72.37  ? 1100 LEU   R CG  1 
ATOM   3344 C  CD1 . LEU   B 2 339 ? 136.058 174.942 185.315 1.00 72.37  ? 1100 LEU   R CD1 1 
ATOM   3345 C  CD2 . LEU   B 2 339 ? 133.675 175.264 184.633 1.00 72.37  ? 1100 LEU   R CD2 1 
ATOM   3346 N  N   . SER   B 2 340 ? 134.948 174.115 180.158 1.00 69.74  ? 1101 SER   R N   1 
ATOM   3347 C  CA  . SER   B 2 340 ? 135.575 173.935 178.861 1.00 69.74  ? 1101 SER   R CA  1 
ATOM   3348 C  C   . SER   B 2 340 ? 137.077 173.745 179.028 1.00 69.74  ? 1101 SER   R C   1 
ATOM   3349 O  O   . SER   B 2 340 ? 137.673 174.149 180.028 1.00 69.74  ? 1101 SER   R O   1 
ATOM   3350 C  CB  . SER   B 2 340 ? 135.293 175.129 177.949 1.00 69.74  ? 1101 SER   R CB  1 
ATOM   3351 O  OG  . SER   B 2 340 ? 136.064 176.255 178.329 1.00 69.74  ? 1101 SER   R OG  1 
ATOM   3352 N  N   . ARG   B 2 341 ? 137.681 173.117 178.021 1.00 65.08  ? 1102 ARG   R N   1 
ATOM   3353 C  CA  . ARG   B 2 341 ? 139.104 172.801 178.062 1.00 65.08  ? 1102 ARG   R CA  1 
ATOM   3354 C  C   . ARG   B 2 341 ? 139.962 174.063 178.030 1.00 65.08  ? 1102 ARG   R C   1 
ATOM   3355 O  O   . ARG   B 2 341 ? 140.990 174.142 178.716 1.00 65.08  ? 1102 ARG   R O   1 
ATOM   3356 C  CB  . ARG   B 2 341 ? 139.435 171.878 176.893 1.00 65.08  ? 1102 ARG   R CB  1 
ATOM   3357 C  CG  . ARG   B 2 341 ? 140.820 171.292 176.879 1.00 65.08  ? 1102 ARG   R CG  1 
ATOM   3358 C  CD  . ARG   B 2 341 ? 140.980 170.456 175.623 1.00 65.08  ? 1102 ARG   R CD  1 
ATOM   3359 N  NE  . ARG   B 2 341 ? 142.338 169.966 175.431 1.00 65.08  ? 1102 ARG   R NE  1 
ATOM   3360 C  CZ  . ARG   B 2 341 ? 142.746 169.318 174.350 1.00 65.08  ? 1102 ARG   R CZ  1 
ATOM   3361 N  NH1 . ARG   B 2 341 ? 141.928 169.080 173.339 1.00 65.08  ? 1102 ARG   R NH1 1 
ATOM   3362 N  NH2 . ARG   B 2 341 ? 144.007 168.901 174.280 1.00 65.08  ? 1102 ARG   R NH2 1 
ATOM   3363 N  N   . GLU   B 2 342 ? 139.552 175.062 177.245 1.00 67.77  ? 1103 GLU   R N   1 
ATOM   3364 C  CA  . GLU   B 2 342 ? 140.311 176.306 177.168 1.00 67.77  ? 1103 GLU   R CA  1 
ATOM   3365 C  C   . GLU   B 2 342 ? 140.232 177.096 178.467 1.00 67.77  ? 1103 GLU   R C   1 
ATOM   3366 O  O   . GLU   B 2 342 ? 141.178 177.810 178.815 1.00 67.77  ? 1103 GLU   R O   1 
ATOM   3367 C  CB  . GLU   B 2 342 ? 139.824 177.164 175.996 1.00 67.77  ? 1103 GLU   R CB  1 
ATOM   3368 C  CG  . GLU   B 2 342 ? 138.308 177.222 175.782 1.00 67.77  ? 1103 GLU   R CG  1 
ATOM   3369 C  CD  . GLU   B 2 342 ? 137.753 176.069 174.954 1.00 67.77  ? 1103 GLU   R CD  1 
ATOM   3370 O  OE1 . GLU   B 2 342 ? 136.734 176.277 174.265 1.00 67.77  ? 1103 GLU   R OE1 1 
ATOM   3371 O  OE2 . GLU   B 2 342 ? 138.327 174.961 174.986 1.00 67.77  ? 1103 GLU   R OE2 1 
ATOM   3372 N  N   . PHE   B 2 343 ? 139.125 176.968 179.200 1.00 64.93  ? 1104 PHE   R N   1 
ATOM   3373 C  CA  . PHE   B 2 343 ? 139.029 177.593 180.514 1.00 64.93  ? 1104 PHE   R CA  1 
ATOM   3374 C  C   . PHE   B 2 343 ? 140.030 176.982 181.490 1.00 64.93  ? 1104 PHE   R C   1 
ATOM   3375 O  O   . PHE   B 2 343 ? 140.662 177.700 182.275 1.00 64.93  ? 1104 PHE   R O   1 
ATOM   3376 C  CB  . PHE   B 2 343 ? 137.600 177.464 181.040 1.00 64.93  ? 1104 PHE   R CB  1 
ATOM   3377 C  CG  . PHE   B 2 343 ? 137.325 178.283 182.266 1.00 64.93  ? 1104 PHE   R CG  1 
ATOM   3378 C  CD1 . PHE   B 2 343 ? 137.984 179.483 182.482 1.00 64.93  ? 1104 PHE   R CD1 1 
ATOM   3379 C  CD2 . PHE   B 2 343 ? 136.399 177.854 183.201 1.00 64.93  ? 1104 PHE   R CD2 1 
ATOM   3380 C  CE1 . PHE   B 2 343 ? 137.729 180.234 183.612 1.00 64.93  ? 1104 PHE   R CE1 1 
ATOM   3381 C  CE2 . PHE   B 2 343 ? 136.139 178.598 184.332 1.00 64.93  ? 1104 PHE   R CE2 1 
ATOM   3382 C  CZ  . PHE   B 2 343 ? 136.803 179.791 184.538 1.00 64.93  ? 1104 PHE   R CZ  1 
ATOM   3383 N  N   . VAL   B 2 344 ? 140.202 175.659 181.445 1.00 60.30  ? 1105 VAL   R N   1 
ATOM   3384 C  CA  . VAL   B 2 344 ? 141.198 175.014 182.293 1.00 60.30  ? 1105 VAL   R CA  1 
ATOM   3385 C  C   . VAL   B 2 344 ? 142.608 175.386 181.849 1.00 60.30  ? 1105 VAL   R C   1 
ATOM   3386 O  O   . VAL   B 2 344 ? 143.511 175.521 182.686 1.00 60.30  ? 1105 VAL   R O   1 
ATOM   3387 C  CB  . VAL   B 2 344 ? 140.980 173.490 182.304 1.00 60.30  ? 1105 VAL   R CB  1 
ATOM   3388 C  CG1 . VAL   B 2 344 ? 141.831 172.834 183.372 1.00 60.30  ? 1105 VAL   R CG1 1 
ATOM   3389 C  CG2 . VAL   B 2 344 ? 139.522 173.179 182.547 1.00 60.30  ? 1105 VAL   R CG2 1 
ATOM   3390 N  N   . ARG   B 2 345 ? 142.824 175.560 180.540 1.00 59.78  ? 1106 ARG   R N   1 
ATOM   3391 C  CA  . ARG   B 2 345 ? 144.120 176.042 180.064 1.00 59.78  ? 1106 ARG   R CA  1 
ATOM   3392 C  C   . ARG   B 2 345 ? 144.418 177.437 180.597 1.00 59.78  ? 1106 ARG   R C   1 
ATOM   3393 O  O   . ARG   B 2 345 ? 145.549 177.727 181.006 1.00 59.78  ? 1106 ARG   R O   1 
ATOM   3394 C  CB  . ARG   B 2 345 ? 144.161 176.040 178.535 1.00 59.78  ? 1106 ARG   R CB  1 
ATOM   3395 C  CG  . ARG   B 2 345 ? 145.347 176.799 177.954 1.00 59.78  ? 1106 ARG   R CG  1 
ATOM   3396 C  CD  . ARG   B 2 345 ? 145.423 176.669 176.452 1.00 59.78  ? 1106 ARG   R CD  1 
ATOM   3397 N  NE  . ARG   B 2 345 ? 144.170 177.032 175.808 1.00 59.78  ? 1106 ARG   R NE  1 
ATOM   3398 C  CZ  . ARG   B 2 345 ? 143.881 176.768 174.543 1.00 59.78  ? 1106 ARG   R CZ  1 
ATOM   3399 N  NH1 . ARG   B 2 345 ? 144.740 176.145 173.755 1.00 59.78  ? 1106 ARG   R NH1 1 
ATOM   3400 N  NH2 . ARG   B 2 345 ? 142.698 177.132 174.057 1.00 59.78  ? 1106 ARG   R NH2 1 
ATOM   3401 N  N   . GLU   B 2 346 ? 143.408 178.309 180.609 1.00 64.84  ? 1107 GLU   R N   1 
ATOM   3402 C  CA  . GLU   B 2 346 ? 143.574 179.638 181.188 1.00 64.84  ? 1107 GLU   R CA  1 
ATOM   3403 C  C   . GLU   B 2 346 ? 143.857 179.553 182.682 1.00 64.84  ? 1107 GLU   R C   1 
ATOM   3404 O  O   . GLU   B 2 346 ? 144.669 180.321 183.209 1.00 64.84  ? 1107 GLU   R O   1 
ATOM   3405 C  CB  . GLU   B 2 346 ? 142.327 180.483 180.917 1.00 64.84  ? 1107 GLU   R CB  1 
ATOM   3406 C  CG  . GLU   B 2 346 ? 142.558 181.994 180.928 1.00 64.84  ? 1107 GLU   R CG  1 
ATOM   3407 C  CD  . GLU   B 2 346 ? 142.703 182.576 182.322 1.00 64.84  ? 1107 GLU   R CD  1 
ATOM   3408 O  OE1 . GLU   B 2 346 ? 141.749 182.469 183.120 1.00 64.84  ? 1107 GLU   R OE1 1 
ATOM   3409 O  OE2 . GLU   B 2 346 ? 143.778 183.131 182.623 1.00 64.84  ? 1107 GLU   R OE2 1 
ATOM   3410 N  N   . LEU   B 2 347 ? 143.197 178.624 183.376 1.00 60.97  ? 1108 LEU   R N   1 
ATOM   3411 C  CA  . LEU   B 2 347 ? 143.387 178.487 184.817 1.00 60.97  ? 1108 LEU   R CA  1 
ATOM   3412 C  C   . LEU   B 2 347 ? 144.785 177.987 185.163 1.00 60.97  ? 1108 LEU   R C   1 
ATOM   3413 O  O   . LEU   B 2 347 ? 145.361 178.402 186.175 1.00 60.97  ? 1108 LEU   R O   1 
ATOM   3414 C  CB  . LEU   B 2 347 ? 142.331 177.550 185.394 1.00 60.97  ? 1108 LEU   R CB  1 
ATOM   3415 C  CG  . LEU   B 2 347 ? 141.003 178.200 185.765 1.00 60.97  ? 1108 LEU   R CG  1 
ATOM   3416 C  CD1 . LEU   B 2 347 ? 139.882 177.186 185.711 1.00 60.97  ? 1108 LEU   R CD1 1 
ATOM   3417 C  CD2 . LEU   B 2 347 ? 141.102 178.808 187.145 1.00 60.97  ? 1108 LEU   R CD2 1 
ATOM   3418 N  N   . TYR   B 2 348 ? 145.338 177.084 184.349 1.00 55.61  ? 1109 TYR   R N   1 
ATOM   3419 C  CA  . TYR   B 2 348 ? 146.636 176.490 184.667 1.00 55.61  ? 1109 TYR   R CA  1 
ATOM   3420 C  C   . TYR   B 2 348 ? 147.759 177.513 184.584 1.00 55.61  ? 1109 TYR   R C   1 
ATOM   3421 O  O   . TYR   B 2 348 ? 148.689 177.489 185.397 1.00 55.61  ? 1109 TYR   R O   1 
ATOM   3422 C  CB  . TYR   B 2 348 ? 146.927 175.334 183.721 1.00 55.61  ? 1109 TYR   R CB  1 
ATOM   3423 C  CG  . TYR   B 2 348 ? 146.301 174.024 184.107 1.00 55.61  ? 1109 TYR   R CG  1 
ATOM   3424 C  CD1 . TYR   B 2 348 ? 146.124 173.677 185.436 1.00 55.61  ? 1109 TYR   R CD1 1 
ATOM   3425 C  CD2 . TYR   B 2 348 ? 145.885 173.131 183.134 1.00 55.61  ? 1109 TYR   R CD2 1 
ATOM   3426 C  CE1 . TYR   B 2 348 ? 145.551 172.476 185.779 1.00 55.61  ? 1109 TYR   R CE1 1 
ATOM   3427 C  CE2 . TYR   B 2 348 ? 145.316 171.937 183.467 1.00 55.61  ? 1109 TYR   R CE2 1 
ATOM   3428 C  CZ  . TYR   B 2 348 ? 145.148 171.614 184.786 1.00 55.61  ? 1109 TYR   R CZ  1 
ATOM   3429 O  OH  . TYR   B 2 348 ? 144.574 170.412 185.103 1.00 55.61  ? 1109 TYR   R OH  1 
ATOM   3430 N  N   . GLY   B 2 349 ? 147.705 178.400 183.597 1.00 60.12  ? 1110 GLY   R N   1 
ATOM   3431 C  CA  . GLY   B 2 349 ? 148.711 179.424 183.421 1.00 60.12  ? 1110 GLY   R CA  1 
ATOM   3432 C  C   . GLY   B 2 349 ? 148.500 180.683 184.220 1.00 60.12  ? 1110 GLY   R C   1 
ATOM   3433 O  O   . GLY   B 2 349 ? 149.291 181.621 184.102 1.00 60.12  ? 1110 GLY   R O   1 
ATOM   3434 N  N   . SER   B 2 350 ? 147.444 180.738 185.029 1.00 62.34  ? 1111 SER   R N   1 
ATOM   3435 C  CA  . SER   B 2 350 ? 147.161 181.885 185.880 1.00 62.34  ? 1111 SER   R CA  1 
ATOM   3436 C  C   . SER   B 2 350 ? 147.525 181.646 187.337 1.00 62.34  ? 1111 SER   R C   1 
ATOM   3437 O  O   . SER   B 2 350 ? 148.075 182.539 187.987 1.00 62.34  ? 1111 SER   R O   1 
ATOM   3438 C  CB  . SER   B 2 350 ? 145.680 182.259 185.787 1.00 62.34  ? 1111 SER   R CB  1 
ATOM   3439 O  OG  . SER   B 2 350 ? 145.239 182.256 184.443 1.00 62.34  ? 1111 SER   R OG  1 
ATOM   3440 N  N   . VAL   B 2 351 ? 147.236 180.459 187.866 1.00 56.92  ? 1112 VAL   R N   1 
ATOM   3441 C  CA  . VAL   B 2 351 ? 147.476 180.163 189.272 1.00 56.92  ? 1112 VAL   R CA  1 
ATOM   3442 C  C   . VAL   B 2 351 ? 148.959 179.912 189.489 1.00 56.92  ? 1112 VAL   R C   1 
ATOM   3443 O  O   . VAL   B 2 351 ? 149.719 179.749 188.530 1.00 56.92  ? 1112 VAL   R O   1 
ATOM   3444 C  CB  . VAL   B 2 351 ? 146.641 178.959 189.740 1.00 56.92  ? 1112 VAL   R CB  1 
ATOM   3445 C  CG1 . VAL   B 2 351 ? 145.179 179.177 189.407 1.00 56.92  ? 1112 VAL   R CG1 1 
ATOM   3446 C  CG2 . VAL   B 2 351 ? 147.154 177.682 189.112 1.00 56.92  ? 1112 VAL   R CG2 1 
ATOM   3447 N  N   . ASP   B 2 352 ? 149.381 179.889 190.750 1.00 58.67  ? 1113 ASP   R N   1 
ATOM   3448 C  CA  . ASP   B 2 352 ? 150.784 179.670 191.073 1.00 58.67  ? 1113 ASP   R CA  1 
ATOM   3449 C  C   . ASP   B 2 352 ? 151.101 178.202 191.314 1.00 58.67  ? 1113 ASP   R C   1 
ATOM   3450 O  O   . ASP   B 2 352 ? 152.144 177.716 190.868 1.00 58.67  ? 1113 ASP   R O   1 
ATOM   3451 C  CB  . ASP   B 2 352 ? 151.177 180.491 192.303 1.00 58.67  ? 1113 ASP   R CB  1 
ATOM   3452 C  CG  . ASP   B 2 352 ? 151.386 181.956 191.985 1.00 58.67  ? 1113 ASP   R CG  1 
ATOM   3453 O  OD1 . ASP   B 2 352 ? 152.484 182.315 191.513 1.00 58.67  ? 1113 ASP   R OD1 1 
ATOM   3454 O  OD2 . ASP   B 2 352 ? 150.452 182.749 192.209 1.00 58.67  ? 1113 ASP   R OD2 1 
ATOM   3455 N  N   . PHE   B 2 353 ? 150.225 177.483 192.010 1.00 54.10  ? 1114 PHE   R N   1 
ATOM   3456 C  CA  . PHE   B 2 353 ? 150.468 176.093 192.360 1.00 54.10  ? 1114 PHE   R CA  1 
ATOM   3457 C  C   . PHE   B 2 353 ? 149.231 175.261 192.067 1.00 54.10  ? 1114 PHE   R C   1 
ATOM   3458 O  O   . PHE   B 2 353 ? 148.111 175.774 192.036 1.00 54.10  ? 1114 PHE   R O   1 
ATOM   3459 C  CB  . PHE   B 2 353 ? 150.850 175.941 193.833 1.00 54.10  ? 1114 PHE   R CB  1 
ATOM   3460 C  CG  . PHE   B 2 353 ? 152.158 176.578 194.192 1.00 54.10  ? 1114 PHE   R CG  1 
ATOM   3461 C  CD1 . PHE   B 2 353 ? 152.219 177.913 194.549 1.00 54.10  ? 1114 PHE   R CD1 1 
ATOM   3462 C  CD2 . PHE   B 2 353 ? 153.326 175.838 194.188 1.00 54.10  ? 1114 PHE   R CD2 1 
ATOM   3463 C  CE1 . PHE   B 2 353 ? 153.421 178.499 194.883 1.00 54.10  ? 1114 PHE   R CE1 1 
ATOM   3464 C  CE2 . PHE   B 2 353 ? 154.532 176.420 194.523 1.00 54.10  ? 1114 PHE   R CE2 1 
ATOM   3465 C  CZ  . PHE   B 2 353 ? 154.578 177.752 194.872 1.00 54.10  ? 1114 PHE   R CZ  1 
ATOM   3466 N  N   . VAL   B 2 354 ? 149.450 173.969 191.831 1.00 51.28  ? 1115 VAL   R N   1 
ATOM   3467 C  CA  . VAL   B 2 354 ? 148.382 173.003 191.596 1.00 51.28  ? 1115 VAL   R CA  1 
ATOM   3468 C  C   . VAL   B 2 354 ? 148.607 171.822 192.527 1.00 51.28  ? 1115 VAL   R C   1 
ATOM   3469 O  O   . VAL   B 2 354 ? 149.709 171.268 192.577 1.00 51.28  ? 1115 VAL   R O   1 
ATOM   3470 C  CB  . VAL   B 2 354 ? 148.336 172.535 190.128 1.00 51.28  ? 1115 VAL   R CB  1 
ATOM   3471 C  CG1 . VAL   B 2 354 ? 147.274 171.473 189.941 1.00 51.28  ? 1115 VAL   R CG1 1 
ATOM   3472 C  CG2 . VAL   B 2 354 ? 148.063 173.697 189.202 1.00 51.28  ? 1115 VAL   R CG2 1 
ATOM   3473 N  N   . ILE   B 2 355 ? 147.568 171.438 193.261 1.00 52.10  ? 1116 ILE   R N   1 
ATOM   3474 C  CA  . ILE   B 2 355 ? 147.637 170.343 194.220 1.00 52.10  ? 1116 ILE   R CA  1 
ATOM   3475 C  C   . ILE   B 2 355 ? 146.969 169.119 193.614 1.00 52.10  ? 1116 ILE   R C   1 
ATOM   3476 O  O   . ILE   B 2 355 ? 145.812 169.182 193.183 1.00 52.10  ? 1116 ILE   R O   1 
ATOM   3477 C  CB  . ILE   B 2 355 ? 146.973 170.732 195.551 1.00 52.10  ? 1116 ILE   R CB  1 
ATOM   3478 C  CG1 . ILE   B 2 355 ? 147.694 171.931 196.163 1.00 52.10  ? 1116 ILE   R CG1 1 
ATOM   3479 C  CG2 . ILE   B 2 355 ? 146.978 169.567 196.514 1.00 52.10  ? 1116 ILE   R CG2 1 
ATOM   3480 C  CD1 . ILE   B 2 355 ? 146.773 172.900 196.835 1.00 52.10  ? 1116 ILE   R CD1 1 
ATOM   3481 N  N   . ILE   B 2 356 ? 147.699 168.008 193.570 1.00 53.90  ? 1117 ILE   R N   1 
ATOM   3482 C  CA  . ILE   B 2 356 ? 147.177 166.742 193.059 1.00 53.90  ? 1117 ILE   R CA  1 
ATOM   3483 C  C   . ILE   B 2 356 ? 147.354 165.689 194.146 1.00 53.90  ? 1117 ILE   R C   1 
ATOM   3484 O  O   . ILE   B 2 356 ? 148.278 164.867 194.067 1.00 53.90  ? 1117 ILE   R O   1 
ATOM   3485 C  CB  . ILE   B 2 356 ? 147.880 166.317 191.759 1.00 53.90  ? 1117 ILE   R CB  1 
ATOM   3486 C  CG1 . ILE   B 2 356 ? 148.073 167.510 190.822 1.00 53.90  ? 1117 ILE   R CG1 1 
ATOM   3487 C  CG2 . ILE   B 2 356 ? 147.081 165.240 191.050 1.00 53.90  ? 1117 ILE   R CG2 1 
ATOM   3488 C  CD1 . ILE   B 2 356 ? 149.114 167.292 189.767 1.00 53.90  ? 1117 ILE   R CD1 1 
ATOM   3489 N  N   . PRO   B 2 357 ? 146.512 165.680 195.185 1.00 54.91  ? 1118 PRO   R N   1 
ATOM   3490 C  CA  . PRO   B 2 357 ? 146.686 164.757 196.309 1.00 54.91  ? 1118 PRO   R CA  1 
ATOM   3491 C  C   . PRO   B 2 357 ? 145.970 163.426 196.109 1.00 54.91  ? 1118 PRO   R C   1 
ATOM   3492 O  O   . PRO   B 2 357 ? 145.282 162.927 197.003 1.00 54.91  ? 1118 PRO   R O   1 
ATOM   3493 C  CB  . PRO   B 2 357 ? 146.085 165.543 197.477 1.00 54.91  ? 1118 PRO   R CB  1 
ATOM   3494 C  CG  . PRO   B 2 357 ? 144.990 166.364 196.825 1.00 54.91  ? 1118 PRO   R CG  1 
ATOM   3495 C  CD  . PRO   B 2 357 ? 145.284 166.473 195.342 1.00 54.91  ? 1118 PRO   R CD  1 
ATOM   3496 N  N   . SER   B 2 358 ? 146.144 162.827 194.937 1.00 58.23  ? 1119 SER   R N   1 
ATOM   3497 C  CA  . SER   B 2 358 ? 145.383 161.636 194.605 1.00 58.23  ? 1119 SER   R CA  1 
ATOM   3498 C  C   . SER   B 2 358 ? 145.978 160.405 195.279 1.00 58.23  ? 1119 SER   R C   1 
ATOM   3499 O  O   . SER   B 2 358 ? 147.127 160.398 195.724 1.00 58.23  ? 1119 SER   R O   1 
ATOM   3500 C  CB  . SER   B 2 358 ? 145.335 161.438 193.092 1.00 58.23  ? 1119 SER   R CB  1 
ATOM   3501 O  OG  . SER   B 2 358 ? 146.637 161.398 192.545 1.00 58.23  ? 1119 SER   R OG  1 
ATOM   3502 N  N   . TYR   B 2 359 ? 145.162 159.357 195.367 1.00 61.98  ? 1120 TYR   R N   1 
ATOM   3503 C  CA  . TYR   B 2 359 ? 145.629 158.062 195.841 1.00 61.98  ? 1120 TYR   R CA  1 
ATOM   3504 C  C   . TYR   B 2 359 ? 146.118 157.193 194.691 1.00 61.98  ? 1120 TYR   R C   1 
ATOM   3505 O  O   . TYR   B 2 359 ? 147.195 156.597 194.771 1.00 61.98  ? 1120 TYR   R O   1 
ATOM   3506 C  CB  . TYR   B 2 359 ? 144.513 157.333 196.591 1.00 61.98  ? 1120 TYR   R CB  1 
ATOM   3507 C  CG  . TYR   B 2 359 ? 143.933 158.090 197.757 1.00 61.98  ? 1120 TYR   R CG  1 
ATOM   3508 C  CD1 . TYR   B 2 359 ? 144.624 158.192 198.955 1.00 61.98  ? 1120 TYR   R CD1 1 
ATOM   3509 C  CD2 . TYR   B 2 359 ? 142.686 158.690 197.665 1.00 61.98  ? 1120 TYR   R CD2 1 
ATOM   3510 C  CE1 . TYR   B 2 359 ? 144.094 158.876 200.024 1.00 61.98  ? 1120 TYR   R CE1 1 
ATOM   3511 C  CE2 . TYR   B 2 359 ? 142.147 159.377 198.728 1.00 61.98  ? 1120 TYR   R CE2 1 
ATOM   3512 C  CZ  . TYR   B 2 359 ? 142.854 159.468 199.905 1.00 61.98  ? 1120 TYR   R CZ  1 
ATOM   3513 O  OH  . TYR   B 2 359 ? 142.317 160.151 200.969 1.00 61.98  ? 1120 TYR   R OH  1 
ATOM   3514 N  N   . PHE   B 2 360 ? 145.336 157.118 193.617 1.00 63.90  ? 1121 PHE   R N   1 
ATOM   3515 C  CA  . PHE   B 2 360 ? 145.637 156.273 192.467 1.00 63.90  ? 1121 PHE   R CA  1 
ATOM   3516 C  C   . PHE   B 2 360 ? 145.654 157.147 191.222 1.00 63.90  ? 1121 PHE   R C   1 
ATOM   3517 O  O   . PHE   B 2 360 ? 144.596 157.549 190.727 1.00 63.90  ? 1121 PHE   R O   1 
ATOM   3518 C  CB  . PHE   B 2 360 ? 144.612 155.148 192.336 1.00 63.90  ? 1121 PHE   R CB  1 
ATOM   3519 C  CG  . PHE   B 2 360 ? 144.840 154.248 191.158 1.00 63.90  ? 1121 PHE   R CG  1 
ATOM   3520 C  CD1 . PHE   B 2 360 ? 146.115 153.830 190.821 1.00 63.90  ? 1121 PHE   R CD1 1 
ATOM   3521 C  CD2 . PHE   B 2 360 ? 143.774 153.810 190.394 1.00 63.90  ? 1121 PHE   R CD2 1 
ATOM   3522 C  CE1 . PHE   B 2 360 ? 146.321 152.999 189.744 1.00 63.90  ? 1121 PHE   R CE1 1 
ATOM   3523 C  CE2 . PHE   B 2 360 ? 143.975 152.980 189.314 1.00 63.90  ? 1121 PHE   R CE2 1 
ATOM   3524 C  CZ  . PHE   B 2 360 ? 145.250 152.572 188.991 1.00 63.90  ? 1121 PHE   R CZ  1 
ATOM   3525 N  N   . GLU   B 2 361 ? 146.850 157.441 190.723 1.00 66.27  ? 1122 GLU   R N   1 
ATOM   3526 C  CA  . GLU   B 2 361 ? 147.029 158.196 189.485 1.00 66.27  ? 1122 GLU   R CA  1 
ATOM   3527 C  C   . GLU   B 2 361 ? 147.815 157.344 188.502 1.00 66.27  ? 1122 GLU   R C   1 
ATOM   3528 O  O   . GLU   B 2 361 ? 149.054 157.279 188.585 1.00 66.27  ? 1122 GLU   R O   1 
ATOM   3529 C  CB  . GLU   B 2 361 ? 147.749 159.515 189.750 1.00 66.27  ? 1122 GLU   R CB  1 
ATOM   3530 C  CG  . GLU   B 2 361 ? 147.443 160.599 188.734 1.00 66.27  ? 1122 GLU   R CG  1 
ATOM   3531 C  CD  . GLU   B 2 361 ? 145.975 160.973 188.695 1.00 66.27  ? 1122 GLU   R CD  1 
ATOM   3532 O  OE1 . GLU   B 2 361 ? 145.537 161.753 189.565 1.00 66.27  ? 1122 GLU   R OE1 1 
ATOM   3533 O  OE2 . GLU   B 2 361 ? 145.262 160.490 187.790 1.00 66.27  ? 1122 GLU   R OE2 1 
ATOM   3534 N  N   . PRO   B 2 362 ? 147.153 156.672 187.563 1.00 65.07  ? 1123 PRO   R N   1 
ATOM   3535 C  CA  . PRO   B 2 362 ? 147.872 155.768 186.658 1.00 65.07  ? 1123 PRO   R CA  1 
ATOM   3536 C  C   . PRO   B 2 362 ? 148.650 156.501 185.577 1.00 65.07  ? 1123 PRO   R C   1 
ATOM   3537 O  O   . PRO   B 2 362 ? 149.662 155.995 185.087 1.00 65.07  ? 1123 PRO   R O   1 
ATOM   3538 C  CB  . PRO   B 2 362 ? 146.753 154.912 186.048 1.00 65.07  ? 1123 PRO   R CB  1 
ATOM   3539 C  CG  . PRO   B 2 362 ? 145.485 155.317 186.749 1.00 65.07  ? 1123 PRO   R CG  1 
ATOM   3540 C  CD  . PRO   B 2 362 ? 145.709 156.677 187.296 1.00 65.07  ? 1123 PRO   R CD  1 
ATOM   3541 N  N   . PHE   B 2 363 ? 148.194 157.687 185.197 1.00 64.30  ? 1124 PHE   R N   1 
ATOM   3542 C  CA  . PHE   B 2 363 ? 148.799 158.413 184.088 1.00 64.30  ? 1124 PHE   R CA  1 
ATOM   3543 C  C   . PHE   B 2 363 ? 149.305 159.793 184.465 1.00 64.30  ? 1124 PHE   R C   1 
ATOM   3544 O  O   . PHE   B 2 363 ? 150.374 160.196 184.002 1.00 64.30  ? 1124 PHE   R O   1 
ATOM   3545 C  CB  . PHE   B 2 363 ? 147.793 158.532 182.937 1.00 64.30  ? 1124 PHE   R CB  1 
ATOM   3546 C  CG  . PHE   B 2 363 ? 147.202 157.221 182.523 1.00 64.30  ? 1124 PHE   R CG  1 
ATOM   3547 C  CD1 . PHE   B 2 363 ? 147.934 156.331 181.759 1.00 64.30  ? 1124 PHE   R CD1 1 
ATOM   3548 C  CD2 . PHE   B 2 363 ? 145.923 156.869 182.912 1.00 64.30  ? 1124 PHE   R CD2 1 
ATOM   3549 C  CE1 . PHE   B 2 363 ? 147.398 155.119 181.384 1.00 64.30  ? 1124 PHE   R CE1 1 
ATOM   3550 C  CE2 . PHE   B 2 363 ? 145.384 155.657 182.539 1.00 64.30  ? 1124 PHE   R CE2 1 
ATOM   3551 C  CZ  . PHE   B 2 363 ? 146.120 154.784 181.773 1.00 64.30  ? 1124 PHE   R CZ  1 
ATOM   3552 N  N   . GLY   B 2 364 ? 148.579 160.524 185.302 1.00 64.81  ? 1125 GLY   R N   1 
ATOM   3553 C  CA  . GLY   B 2 364 ? 148.979 161.875 185.649 1.00 64.81  ? 1125 GLY   R CA  1 
ATOM   3554 C  C   . GLY   B 2 364 ? 148.905 162.859 184.503 1.00 64.81  ? 1125 GLY   R C   1 
ATOM   3555 O  O   . GLY   B 2 364 ? 149.820 163.672 184.332 1.00 64.81  ? 1125 GLY   R O   1 
ATOM   3556 N  N   . LEU   B 2 365 ? 147.837 162.799 183.704 1.00 62.88  ? 1126 LEU   R N   1 
ATOM   3557 C  CA  . LEU   B 2 365 ? 147.662 163.769 182.630 1.00 62.88  ? 1126 LEU   R CA  1 
ATOM   3558 C  C   . LEU   B 2 365 ? 147.397 165.164 183.176 1.00 62.88  ? 1126 LEU   R C   1 
ATOM   3559 O  O   . LEU   B 2 365 ? 147.746 166.159 182.530 1.00 62.88  ? 1126 LEU   R O   1 
ATOM   3560 C  CB  . LEU   B 2 365 ? 146.522 163.339 181.710 1.00 62.88  ? 1126 LEU   R CB  1 
ATOM   3561 C  CG  . LEU   B 2 365 ? 146.443 161.858 181.346 1.00 62.88  ? 1126 LEU   R CG  1 
ATOM   3562 C  CD1 . LEU   B 2 365 ? 145.146 161.561 180.616 1.00 62.88  ? 1126 LEU   R CD1 1 
ATOM   3563 C  CD2 . LEU   B 2 365 ? 147.635 161.455 180.500 1.00 62.88  ? 1126 LEU   R CD2 1 
ATOM   3564 N  N   . VAL   B 2 366 ? 146.787 165.252 184.360 1.00 59.65  ? 1127 VAL   R N   1 
ATOM   3565 C  CA  . VAL   B 2 366 ? 146.549 166.545 184.994 1.00 59.65  ? 1127 VAL   R CA  1 
ATOM   3566 C  C   . VAL   B 2 366 ? 147.869 167.222 185.353 1.00 59.65  ? 1127 VAL   R C   1 
ATOM   3567 O  O   . VAL   B 2 366 ? 148.016 168.442 185.203 1.00 59.65  ? 1127 VAL   R O   1 
ATOM   3568 C  CB  . VAL   B 2 366 ? 145.602 166.371 186.202 1.00 59.65  ? 1127 VAL   R CB  1 
ATOM   3569 C  CG1 . VAL   B 2 366 ? 146.216 165.522 187.303 1.00 59.65  ? 1127 VAL   R CG1 1 
ATOM   3570 C  CG2 . VAL   B 2 366 ? 145.197 167.713 186.761 1.00 59.65  ? 1127 VAL   R CG2 1 
ATOM   3571 N  N   . ALA   B 2 367 ? 148.871 166.438 185.762 1.00 60.24  ? 1128 ALA   R N   1 
ATOM   3572 C  CA  . ALA   B 2 367 ? 150.184 166.999 186.054 1.00 60.24  ? 1128 ALA   R CA  1 
ATOM   3573 C  C   . ALA   B 2 367 ? 150.871 167.485 184.787 1.00 60.24  ? 1128 ALA   R C   1 
ATOM   3574 O  O   . ALA   B 2 367 ? 151.528 168.530 184.799 1.00 60.24  ? 1128 ALA   R O   1 
ATOM   3575 C  CB  . ALA   B 2 367 ? 151.052 165.969 186.770 1.00 60.24  ? 1128 ALA   R CB  1 
ATOM   3576 N  N   . LEU   B 2 368 ? 150.728 166.743 183.686 1.00 59.91  ? 1129 LEU   R N   1 
ATOM   3577 C  CA  . LEU   B 2 368 ? 151.308 167.171 182.416 1.00 59.91  ? 1129 LEU   R CA  1 
ATOM   3578 C  C   . LEU   B 2 368 ? 150.682 168.471 181.933 1.00 59.91  ? 1129 LEU   R C   1 
ATOM   3579 O  O   . LEU   B 2 368 ? 151.390 169.398 181.521 1.00 59.91  ? 1129 LEU   R O   1 
ATOM   3580 C  CB  . LEU   B 2 368 ? 151.135 166.080 181.364 1.00 59.91  ? 1129 LEU   R CB  1 
ATOM   3581 C  CG  . LEU   B 2 368 ? 152.184 164.978 181.393 1.00 59.91  ? 1129 LEU   R CG  1 
ATOM   3582 C  CD1 . LEU   B 2 368 ? 151.783 163.813 180.507 1.00 59.91  ? 1129 LEU   R CD1 1 
ATOM   3583 C  CD2 . LEU   B 2 368 ? 153.514 165.554 180.968 1.00 59.91  ? 1129 LEU   R CD2 1 
ATOM   3584 N  N   . GLU   B 2 369 ? 149.351 168.560 181.989 1.00 59.77  ? 1130 GLU   R N   1 
ATOM   3585 C  CA  . GLU   B 2 369 ? 148.679 169.777 181.547 1.00 59.77  ? 1130 GLU   R CA  1 
ATOM   3586 C  C   . GLU   B 2 369 ? 148.993 170.960 182.452 1.00 59.77  ? 1130 GLU   R C   1 
ATOM   3587 O  O   . GLU   B 2 369 ? 149.076 172.095 181.971 1.00 59.77  ? 1130 GLU   R O   1 
ATOM   3588 C  CB  . GLU   B 2 369 ? 147.173 169.555 181.476 1.00 59.77  ? 1130 GLU   R CB  1 
ATOM   3589 C  CG  . GLU   B 2 369 ? 146.745 168.504 180.482 1.00 59.77  ? 1130 GLU   R CG  1 
ATOM   3590 C  CD  . GLU   B 2 369 ? 145.421 167.876 180.853 1.00 59.77  ? 1130 GLU   R CD  1 
ATOM   3591 O  OE1 . GLU   B 2 369 ? 144.686 168.476 181.664 1.00 59.77  ? 1130 GLU   R OE1 1 
ATOM   3592 O  OE2 . GLU   B 2 369 ? 145.115 166.783 180.334 1.00 59.77  ? 1130 GLU   R OE2 1 
ATOM   3593 N  N   . ALA   B 2 370 ? 149.163 170.726 183.755 1.00 58.80  ? 1131 ALA   R N   1 
ATOM   3594 C  CA  . ALA   B 2 370 ? 149.538 171.816 184.648 1.00 58.80  ? 1131 ALA   R CA  1 
ATOM   3595 C  C   . ALA   B 2 370 ? 150.960 172.287 184.377 1.00 58.80  ? 1131 ALA   R C   1 
ATOM   3596 O  O   . ALA   B 2 370 ? 151.205 173.488 184.225 1.00 58.80  ? 1131 ALA   R O   1 
ATOM   3597 C  CB  . ALA   B 2 370 ? 149.384 171.380 186.104 1.00 58.80  ? 1131 ALA   R CB  1 
ATOM   3598 N  N   . MET   B 2 371 ? 151.911 171.354 184.297 1.00 60.77  ? 1132 MET   R N   1 
ATOM   3599 C  CA  . MET   B 2 371 ? 153.313 171.710 184.132 1.00 60.77  ? 1132 MET   R CA  1 
ATOM   3600 C  C   . MET   B 2 371 ? 153.632 172.281 182.758 1.00 60.77  ? 1132 MET   R C   1 
ATOM   3601 O  O   . MET   B 2 371 ? 154.592 173.049 182.639 1.00 60.77  ? 1132 MET   R O   1 
ATOM   3602 C  CB  . MET   B 2 371 ? 154.196 170.492 184.394 1.00 60.77  ? 1132 MET   R CB  1 
ATOM   3603 C  CG  . MET   B 2 371 ? 154.187 169.996 185.817 1.00 60.77  ? 1132 MET   R CG  1 
ATOM   3604 S  SD  . MET   B 2 371 ? 155.190 168.512 185.992 1.00 60.77  ? 1132 MET   R SD  1 
ATOM   3605 C  CE  . MET   B 2 371 ? 156.825 169.201 185.784 1.00 60.77  ? 1132 MET   R CE  1 
ATOM   3606 N  N   . CYS   B 2 372 ? 152.867 171.925 181.721 1.00 59.55  ? 1133 CYS   R N   1 
ATOM   3607 C  CA  . CYS   B 2 372 ? 153.118 172.490 180.399 1.00 59.55  ? 1133 CYS   R CA  1 
ATOM   3608 C  C   . CYS   B 2 372 ? 152.819 173.982 180.355 1.00 59.55  ? 1133 CYS   R C   1 
ATOM   3609 O  O   . CYS   B 2 372 ? 153.436 174.713 179.572 1.00 59.55  ? 1133 CYS   R O   1 
ATOM   3610 C  CB  . CYS   B 2 372 ? 152.284 171.762 179.345 1.00 59.55  ? 1133 CYS   R CB  1 
ATOM   3611 S  SG  . CYS   B 2 372 ? 152.989 170.216 178.735 1.00 59.55  ? 1133 CYS   R SG  1 
ATOM   3612 N  N   . LEU   B 2 373 ? 151.887 174.449 181.180 1.00 56.61  ? 1134 LEU   R N   1 
ATOM   3613 C  CA  . LEU   B 2 373 ? 151.480 175.845 181.209 1.00 56.61  ? 1134 LEU   R CA  1 
ATOM   3614 C  C   . LEU   B 2 373 ? 152.148 176.630 182.328 1.00 56.61  ? 1134 LEU   R C   1 
ATOM   3615 O  O   . LEU   B 2 373 ? 151.750 177.766 182.596 1.00 56.61  ? 1134 LEU   R O   1 
ATOM   3616 C  CB  . LEU   B 2 373 ? 149.960 175.935 181.327 1.00 56.61  ? 1134 LEU   R CB  1 
ATOM   3617 C  CG  . LEU   B 2 373 ? 149.247 175.665 180.008 1.00 56.61  ? 1134 LEU   R CG  1 
ATOM   3618 C  CD1 . LEU   B 2 373 ? 147.835 175.205 180.219 1.00 56.61  ? 1134 LEU   R CD1 1 
ATOM   3619 C  CD2 . LEU   B 2 373 ? 149.237 176.946 179.230 1.00 56.61  ? 1134 LEU   R CD2 1 
ATOM   3620 N  N   . GLY   B 2 374 ? 153.151 176.055 182.982 1.00 60.98  ? 1135 GLY   R N   1 
ATOM   3621 C  CA  . GLY   B 2 374 ? 153.867 176.755 184.026 1.00 60.98  ? 1135 GLY   R CA  1 
ATOM   3622 C  C   . GLY   B 2 374 ? 153.083 176.872 185.314 1.00 60.98  ? 1135 GLY   R C   1 
ATOM   3623 O  O   . GLY   B 2 374 ? 152.720 177.974 185.729 1.00 60.98  ? 1135 GLY   R O   1 
ATOM   3624 N  N   . ALA   B 2 375 ? 152.801 175.739 185.948 1.00 54.97  ? 1136 ALA   R N   1 
ATOM   3625 C  CA  . ALA   B 2 375 ? 152.107 175.714 187.231 1.00 54.97  ? 1136 ALA   R CA  1 
ATOM   3626 C  C   . ALA   B 2 375 ? 152.803 174.682 188.102 1.00 54.97  ? 1136 ALA   R C   1 
ATOM   3627 O  O   . ALA   B 2 375 ? 152.757 173.486 187.802 1.00 54.97  ? 1136 ALA   R O   1 
ATOM   3628 C  CB  . ALA   B 2 375 ? 150.627 175.384 187.060 1.00 54.97  ? 1136 ALA   R CB  1 
ATOM   3629 N  N   . ILE   B 2 376 ? 153.442 175.141 189.173 1.00 58.16  ? 1137 ILE   R N   1 
ATOM   3630 C  CA  . ILE   B 2 376 ? 154.288 174.289 190.005 1.00 58.16  ? 1137 ILE   R CA  1 
ATOM   3631 C  C   . ILE   B 2 376 ? 153.423 173.312 190.790 1.00 58.16  ? 1137 ILE   R C   1 
ATOM   3632 O  O   . ILE   B 2 376 ? 152.574 173.736 191.583 1.00 58.16  ? 1137 ILE   R O   1 
ATOM   3633 C  CB  . ILE   B 2 376 ? 155.156 175.135 190.945 1.00 58.16  ? 1137 ILE   R CB  1 
ATOM   3634 C  CG1 . ILE   B 2 376 ? 156.075 176.040 190.130 1.00 58.16  ? 1137 ILE   R CG1 1 
ATOM   3635 C  CG2 . ILE   B 2 376 ? 155.958 174.243 191.866 1.00 58.16  ? 1137 ILE   R CG2 1 
ATOM   3636 C  CD1 . ILE   B 2 376 ? 156.424 177.318 190.825 1.00 58.16  ? 1137 ILE   R CD1 1 
ATOM   3637 N  N   . PRO   B 2 377 ? 153.608 172.005 190.617 1.00 55.87  ? 1138 PRO   R N   1 
ATOM   3638 C  CA  . PRO   B 2 377 ? 152.739 171.039 191.294 1.00 55.87  ? 1138 PRO   R CA  1 
ATOM   3639 C  C   . PRO   B 2 377 ? 153.210 170.682 192.694 1.00 55.87  ? 1138 PRO   R C   1 
ATOM   3640 O  O   . PRO   B 2 377 ? 154.405 170.563 192.974 1.00 55.87  ? 1138 PRO   R O   1 
ATOM   3641 C  CB  . PRO   B 2 377 ? 152.808 169.817 190.369 1.00 55.87  ? 1138 PRO   R CB  1 
ATOM   3642 C  CG  . PRO   B 2 377 ? 154.142 169.904 189.738 1.00 55.87  ? 1138 PRO   R CG  1 
ATOM   3643 C  CD  . PRO   B 2 377 ? 154.545 171.354 189.689 1.00 55.87  ? 1138 PRO   R CD  1 
ATOM   3644 N  N   . ILE   B 2 378 ? 152.239 170.531 193.585 1.00 58.98  ? 1139 ILE   R N   1 
ATOM   3645 C  CA  . ILE   B 2 378 ? 152.452 169.977 194.920 1.00 58.98  ? 1139 ILE   R CA  1 
ATOM   3646 C  C   . ILE   B 2 378 ? 151.596 168.719 194.974 1.00 58.98  ? 1139 ILE   R C   1 
ATOM   3647 O  O   . ILE   B 2 378 ? 150.424 168.758 195.353 1.00 58.98  ? 1139 ILE   R O   1 
ATOM   3648 C  CB  . ILE   B 2 378 ? 152.075 170.957 196.033 1.00 58.98  ? 1139 ILE   R CB  1 
ATOM   3649 C  CG1 . ILE   B 2 378 ? 152.622 172.351 195.738 1.00 58.98  ? 1139 ILE   R CG1 1 
ATOM   3650 C  CG2 . ILE   B 2 378 ? 152.583 170.461 197.372 1.00 58.98  ? 1139 ILE   R CG2 1 
ATOM   3651 C  CD1 . ILE   B 2 378 ? 151.897 173.439 196.480 1.00 58.98  ? 1139 ILE   R CD1 1 
ATOM   3652 N  N   . ALA   B 2 379 ? 152.180 167.588 194.605 1.00 60.04  ? 1140 ALA   R N   1 
ATOM   3653 C  CA  . ALA   B 2 379 ? 151.398 166.401 194.303 1.00 60.04  ? 1140 ALA   R CA  1 
ATOM   3654 C  C   . ALA   B 2 379 ? 151.795 165.238 195.198 1.00 60.04  ? 1140 ALA   R C   1 
ATOM   3655 O  O   . ALA   B 2 379 ? 152.799 165.277 195.908 1.00 60.04  ? 1140 ALA   R O   1 
ATOM   3656 C  CB  . ALA   B 2 379 ? 151.553 166.008 192.831 1.00 60.04  ? 1140 ALA   R CB  1 
ATOM   3657 N  N   . SER   B 2 380 ? 150.978 164.192 195.145 1.00 61.35  ? 1141 SER   R N   1 
ATOM   3658 C  CA  . SER   B 2 380 ? 151.228 162.967 195.886 1.00 61.35  ? 1141 SER   R CA  1 
ATOM   3659 C  C   . SER   B 2 380 ? 152.119 162.039 195.074 1.00 61.35  ? 1141 SER   R C   1 
ATOM   3660 O  O   . SER   B 2 380 ? 151.930 161.879 193.866 1.00 61.35  ? 1141 SER   R O   1 
ATOM   3661 C  CB  . SER   B 2 380 ? 149.911 162.269 196.224 1.00 61.35  ? 1141 SER   R CB  1 
ATOM   3662 O  OG  . SER   B 2 380 ? 150.134 160.948 196.677 1.00 61.35  ? 1141 SER   R OG  1 
ATOM   3663 N  N   . ALA   B 2 381 ? 153.094 161.427 195.745 1.00 60.35  ? 1142 ALA   R N   1 
ATOM   3664 C  CA  . ALA   B 2 381 ? 154.049 160.533 195.091 1.00 60.35  ? 1142 ALA   R CA  1 
ATOM   3665 C  C   . ALA   B 2 381 ? 153.449 159.132 194.983 1.00 60.35  ? 1142 ALA   R C   1 
ATOM   3666 O  O   . ALA   B 2 381 ? 153.825 158.194 195.688 1.00 60.35  ? 1142 ALA   R O   1 
ATOM   3667 C  CB  . ALA   B 2 381 ? 155.369 160.515 195.847 1.00 60.35  ? 1142 ALA   R CB  1 
ATOM   3668 N  N   . VAL   B 2 382 ? 152.485 159.001 194.075 1.00 63.58  ? 1143 VAL   R N   1 
ATOM   3669 C  CA  . VAL   B 2 382 ? 151.833 157.728 193.802 1.00 63.58  ? 1143 VAL   R CA  1 
ATOM   3670 C  C   . VAL   B 2 382 ? 151.697 157.547 192.298 1.00 63.58  ? 1143 VAL   R C   1 
ATOM   3671 O  O   . VAL   B 2 382 ? 151.516 158.514 191.551 1.00 63.58  ? 1143 VAL   R O   1 
ATOM   3672 C  CB  . VAL   B 2 382 ? 150.446 157.616 194.479 1.00 63.58  ? 1143 VAL   R CB  1 
ATOM   3673 C  CG1 . VAL   B 2 382 ? 150.586 157.447 195.978 1.00 63.58  ? 1143 VAL   R CG1 1 
ATOM   3674 C  CG2 . VAL   B 2 382 ? 149.598 158.831 194.157 1.00 63.58  ? 1143 VAL   R CG2 1 
ATOM   3675 N  N   . GLY   B 2 383 ? 151.790 156.290 191.862 1.00 65.58  ? 1144 GLY   R N   1 
ATOM   3676 C  CA  . GLY   B 2 383 ? 151.471 155.928 190.488 1.00 65.58  ? 1144 GLY   R CA  1 
ATOM   3677 C  C   . GLY   B 2 383 ? 152.383 156.586 189.475 1.00 65.58  ? 1144 GLY   R C   1 
ATOM   3678 O  O   . GLY   B 2 383 ? 153.611 156.578 189.606 1.00 65.58  ? 1144 GLY   R O   1 
ATOM   3679 N  N   . GLY   B 2 384 ? 151.771 157.179 188.452 1.00 63.98  ? 1145 GLY   R N   1 
ATOM   3680 C  CA  . GLY   B 2 384 ? 152.511 157.887 187.430 1.00 63.98  ? 1145 GLY   R CA  1 
ATOM   3681 C  C   . GLY   B 2 384 ? 152.991 159.262 187.827 1.00 63.98  ? 1145 GLY   R C   1 
ATOM   3682 O  O   . GLY   B 2 384 ? 153.690 159.907 187.042 1.00 63.98  ? 1145 GLY   R O   1 
ATOM   3683 N  N   . LEU   B 2 385 ? 152.622 159.733 189.018 1.00 62.20  ? 1146 LEU   R N   1 
ATOM   3684 C  CA  . LEU   B 2 385 ? 153.118 161.008 189.516 1.00 62.20  ? 1146 LEU   R CA  1 
ATOM   3685 C  C   . LEU   B 2 385 ? 154.509 160.903 190.123 1.00 62.20  ? 1146 LEU   R C   1 
ATOM   3686 O  O   . LEU   B 2 385 ? 155.141 161.937 190.359 1.00 62.20  ? 1146 LEU   R O   1 
ATOM   3687 C  CB  . LEU   B 2 385 ? 152.154 161.586 190.553 1.00 62.20  ? 1146 LEU   R CB  1 
ATOM   3688 C  CG  . LEU   B 2 385 ? 150.743 161.919 190.072 1.00 62.20  ? 1146 LEU   R CG  1 
ATOM   3689 C  CD1 . LEU   B 2 385 ? 149.843 162.237 191.247 1.00 62.20  ? 1146 LEU   R CD1 1 
ATOM   3690 C  CD2 . LEU   B 2 385 ? 150.782 163.080 189.104 1.00 62.20  ? 1146 LEU   R CD2 1 
ATOM   3691 N  N   . ARG   B 2 386 ? 154.991 159.686 190.386 1.00 65.28  ? 1147 ARG   R N   1 
ATOM   3692 C  CA  . ARG   B 2 386 ? 156.315 159.519 190.975 1.00 65.28  ? 1147 ARG   R CA  1 
ATOM   3693 C  C   . ARG   B 2 386 ? 157.416 159.899 189.996 1.00 65.28  ? 1147 ARG   R C   1 
ATOM   3694 O  O   . ARG   B 2 386 ? 158.376 160.583 190.367 1.00 65.28  ? 1147 ARG   R O   1 
ATOM   3695 C  CB  . ARG   B 2 386 ? 156.504 158.076 191.440 1.00 65.28  ? 1147 ARG   R CB  1 
ATOM   3696 C  CG  . ARG   B 2 386 ? 155.639 157.677 192.614 1.00 65.28  ? 1147 ARG   R CG  1 
ATOM   3697 C  CD  . ARG   B 2 386 ? 155.941 156.256 193.061 1.00 65.28  ? 1147 ARG   R CD  1 
ATOM   3698 N  NE  . ARG   B 2 386 ? 155.510 155.262 192.085 1.00 65.28  ? 1147 ARG   R NE  1 
ATOM   3699 C  CZ  . ARG   B 2 386 ? 156.331 154.490 191.386 1.00 65.28  ? 1147 ARG   R CZ  1 
ATOM   3700 N  NH1 . ARG   B 2 386 ? 157.644 154.597 191.499 1.00 65.28  ? 1147 ARG   R NH1 1 
ATOM   3701 N  NH2 . ARG   B 2 386 ? 155.821 153.591 190.550 1.00 65.28  ? 1147 ARG   R NH2 1 
ATOM   3702 N  N   . ASP   B 2 387 ? 157.289 159.473 188.741 1.00 68.67  ? 1148 ASP   R N   1 
ATOM   3703 C  CA  . ASP   B 2 387 ? 158.365 159.565 187.765 1.00 68.67  ? 1148 ASP   R CA  1 
ATOM   3704 C  C   . ASP   B 2 387 ? 158.182 160.718 186.787 1.00 68.67  ? 1148 ASP   R C   1 
ATOM   3705 O  O   . ASP   B 2 387 ? 158.829 160.737 185.735 1.00 68.67  ? 1148 ASP   R O   1 
ATOM   3706 C  CB  . ASP   B 2 387 ? 158.493 158.241 187.013 1.00 68.67  ? 1148 ASP   R CB  1 
ATOM   3707 C  CG  . ASP   B 2 387 ? 157.151 157.657 186.633 1.00 68.67  ? 1148 ASP   R CG  1 
ATOM   3708 O  OD1 . ASP   B 2 387 ? 156.119 158.278 186.958 1.00 68.67  ? 1148 ASP   R OD1 1 
ATOM   3709 O  OD2 . ASP   B 2 387 ? 157.126 156.567 186.028 1.00 68.67  ? 1148 ASP   R OD2 1 
ATOM   3710 N  N   . ILE   B 2 388 ? 157.318 161.678 187.108 1.00 65.75  ? 1149 ILE   R N   1 
ATOM   3711 C  CA  . ILE   B 2 388 ? 157.161 162.864 186.286 1.00 65.75  ? 1149 ILE   R CA  1 
ATOM   3712 C  C   . ILE   B 2 388 ? 157.652 164.130 186.987 1.00 65.75  ? 1149 ILE   R C   1 
ATOM   3713 O  O   . ILE   B 2 388 ? 158.247 164.993 186.330 1.00 65.75  ? 1149 ILE   R O   1 
ATOM   3714 C  CB  . ILE   B 2 388 ? 155.694 163.015 185.819 1.00 65.75  ? 1149 ILE   R CB  1 
ATOM   3715 C  CG1 . ILE   B 2 388 ? 155.520 164.221 184.900 1.00 65.75  ? 1149 ILE   R CG1 1 
ATOM   3716 C  CG2 . ILE   B 2 388 ? 154.735 163.081 186.986 1.00 65.75  ? 1149 ILE   R CG2 1 
ATOM   3717 C  CD1 . ILE   B 2 388 ? 154.111 164.415 184.457 1.00 65.75  ? 1149 ILE   R CD1 1 
ATOM   3718 N  N   . ILE   B 2 389 ? 157.472 164.249 188.300 1.00 70.33  ? 1150 ILE   R N   1 
ATOM   3719 C  CA  . ILE   B 2 389 ? 157.909 165.414 189.058 1.00 70.33  ? 1150 ILE   R CA  1 
ATOM   3720 C  C   . ILE   B 2 389 ? 159.206 165.052 189.763 1.00 70.33  ? 1150 ILE   R C   1 
ATOM   3721 O  O   . ILE   B 2 389 ? 159.255 164.086 190.534 1.00 70.33  ? 1150 ILE   R O   1 
ATOM   3722 C  CB  . ILE   B 2 389 ? 156.847 165.875 190.066 1.00 70.33  ? 1150 ILE   R CB  1 
ATOM   3723 C  CG1 . ILE   B 2 389 ? 155.520 166.144 189.360 1.00 70.33  ? 1150 ILE   R CG1 1 
ATOM   3724 C  CG2 . ILE   B 2 389 ? 157.316 167.121 190.794 1.00 70.33  ? 1150 ILE   R CG2 1 
ATOM   3725 C  CD1 . ILE   B 2 389 ? 154.340 166.195 190.295 1.00 70.33  ? 1150 ILE   R CD1 1 
ATOM   3726 N  N   . THR   B 2 390 ? 160.252 165.820 189.496 1.00 74.78  ? 1151 THR   R N   1 
ATOM   3727 C  CA  . THR   B 2 390 ? 161.539 165.617 190.138 1.00 74.78  ? 1151 THR   R CA  1 
ATOM   3728 C  C   . THR   B 2 390 ? 161.622 166.512 191.374 1.00 74.78  ? 1151 THR   R C   1 
ATOM   3729 O  O   . THR   B 2 390 ? 160.644 167.146 191.775 1.00 74.78  ? 1151 THR   R O   1 
ATOM   3730 C  CB  . THR   B 2 390 ? 162.666 165.890 189.148 1.00 74.78  ? 1151 THR   R CB  1 
ATOM   3731 O  OG1 . THR   B 2 390 ? 162.468 167.171 188.544 1.00 74.78  ? 1151 THR   R OG1 1 
ATOM   3732 C  CG2 . THR   B 2 390 ? 162.676 164.832 188.060 1.00 74.78  ? 1151 THR   R CG2 1 
ATOM   3733 N  N   . ASN   B 2 391 ? 162.798 166.575 191.995 1.00 77.76  ? 1152 ASN   R N   1 
ATOM   3734 C  CA  . ASN   B 2 391 ? 162.966 167.399 193.183 1.00 77.76  ? 1152 ASN   R CA  1 
ATOM   3735 C  C   . ASN   B 2 391 ? 163.087 168.881 192.864 1.00 77.76  ? 1152 ASN   R C   1 
ATOM   3736 O  O   . ASN   B 2 391 ? 163.042 169.701 193.787 1.00 77.76  ? 1152 ASN   R O   1 
ATOM   3737 C  CB  . ASN   B 2 391 ? 164.192 166.941 193.973 1.00 77.76  ? 1152 ASN   R CB  1 
ATOM   3738 C  CG  . ASN   B 2 391 ? 163.839 165.972 195.082 1.00 77.76  ? 1152 ASN   R CG  1 
ATOM   3739 O  OD1 . ASN   B 2 391 ? 163.063 166.296 195.980 1.00 77.76  ? 1152 ASN   R OD1 1 
ATOM   3740 N  ND2 . ASN   B 2 391 ? 164.407 164.773 195.023 1.00 77.76  ? 1152 ASN   R ND2 1 
ATOM   3741 N  N   . GLU   B 2 392 ? 163.245 169.243 191.593 1.00 77.94  ? 1153 GLU   R N   1 
ATOM   3742 C  CA  . GLU   B 2 392 ? 163.337 170.635 191.177 1.00 77.94  ? 1153 GLU   R CA  1 
ATOM   3743 C  C   . GLU   B 2 392 ? 162.184 171.044 190.271 1.00 77.94  ? 1153 GLU   R C   1 
ATOM   3744 O  O   . GLU   B 2 392 ? 162.212 172.140 189.703 1.00 77.94  ? 1153 GLU   R O   1 
ATOM   3745 C  CB  . GLU   B 2 392 ? 164.672 170.886 190.475 1.00 77.94  ? 1153 GLU   R CB  1 
ATOM   3746 C  CG  . GLU   B 2 392 ? 164.849 170.096 189.189 1.00 77.94  ? 1153 GLU   R CG  1 
ATOM   3747 C  CD  . GLU   B 2 392 ? 165.573 168.781 189.402 1.00 77.94  ? 1153 GLU   R CD  1 
ATOM   3748 O  OE1 . GLU   B 2 392 ? 165.074 167.948 190.186 1.00 77.94  ? 1153 GLU   R OE1 1 
ATOM   3749 O  OE2 . GLU   B 2 392 ? 166.640 168.581 188.785 1.00 77.94  ? 1153 GLU   R OE2 1 
ATOM   3750 N  N   . THR   B 2 393 ? 161.169 170.191 190.126 1.00 74.88  ? 1154 THR   R N   1 
ATOM   3751 C  CA  . THR   B 2 393 ? 160.010 170.485 189.292 1.00 74.88  ? 1154 THR   R CA  1 
ATOM   3752 C  C   . THR   B 2 393 ? 158.710 170.449 190.087 1.00 74.88  ? 1154 THR   R C   1 
ATOM   3753 O  O   . THR   B 2 393 ? 157.637 170.297 189.500 1.00 74.88  ? 1154 THR   R O   1 
ATOM   3754 C  CB  . THR   B 2 393 ? 159.926 169.511 188.114 1.00 74.88  ? 1154 THR   R CB  1 
ATOM   3755 O  OG1 . THR   B 2 393 ? 160.031 168.164 188.593 1.00 74.88  ? 1154 THR   R OG1 1 
ATOM   3756 C  CG2 . THR   B 2 393 ? 161.042 169.781 187.114 1.00 74.88  ? 1154 THR   R CG2 1 
ATOM   3757 N  N   . GLY   B 2 394 ? 158.782 170.577 191.401 1.00 70.04  ? 1155 GLY   R N   1 
ATOM   3758 C  CA  . GLY   B 2 394 ? 157.597 170.581 192.229 1.00 70.04  ? 1155 GLY   R CA  1 
ATOM   3759 C  C   . GLY   B 2 394 ? 157.903 169.998 193.593 1.00 70.04  ? 1155 GLY   R C   1 
ATOM   3760 O  O   . GLY   B 2 394 ? 159.055 169.771 193.947 1.00 70.04  ? 1155 GLY   R O   1 
ATOM   3761 N  N   . ILE   B 2 395 ? 156.836 169.762 194.353 1.00 66.98  ? 1156 ILE   R N   1 
ATOM   3762 C  CA  . ILE   B 2 395 ? 156.924 169.243 195.713 1.00 66.98  ? 1156 ILE   R CA  1 
ATOM   3763 C  C   . ILE   B 2 395 ? 156.118 167.953 195.794 1.00 66.98  ? 1156 ILE   R C   1 
ATOM   3764 O  O   . ILE   B 2 395 ? 155.030 167.850 195.216 1.00 66.98  ? 1156 ILE   R O   1 
ATOM   3765 C  CB  . ILE   B 2 395 ? 156.429 170.278 196.748 1.00 66.98  ? 1156 ILE   R CB  1 
ATOM   3766 C  CG1 . ILE   B 2 395 ? 157.145 171.615 196.554 1.00 66.98  ? 1156 ILE   R CG1 1 
ATOM   3767 C  CG2 . ILE   B 2 395 ? 156.665 169.790 198.163 1.00 66.98  ? 1156 ILE   R CG2 1 
ATOM   3768 C  CD1 . ILE   B 2 395 ? 156.558 172.745 197.358 1.00 66.98  ? 1156 ILE   R CD1 1 
ATOM   3769 N  N   . LEU   B 2 396 ? 156.669 166.961 196.488 1.00 67.81  ? 1157 LEU   R N   1 
ATOM   3770 C  CA  . LEU   B 2 396 ? 156.044 165.655 196.635 1.00 67.81  ? 1157 LEU   R CA  1 
ATOM   3771 C  C   . LEU   B 2 396 ? 155.612 165.456 198.081 1.00 67.81  ? 1157 LEU   R C   1 
ATOM   3772 O  O   . LEU   B 2 396 ? 156.333 165.826 199.011 1.00 67.81  ? 1157 LEU   R O   1 
ATOM   3773 C  CB  . LEU   B 2 396 ? 156.997 164.528 196.223 1.00 67.81  ? 1157 LEU   R CB  1 
ATOM   3774 C  CG  . LEU   B 2 396 ? 157.182 164.162 194.744 1.00 67.81  ? 1157 LEU   R CG  1 
ATOM   3775 C  CD1 . LEU   B 2 396 ? 155.867 163.740 194.110 1.00 67.81  ? 1157 LEU   R CD1 1 
ATOM   3776 C  CD2 . LEU   B 2 396 ? 157.853 165.262 193.939 1.00 67.81  ? 1157 LEU   R CD2 1 
ATOM   3777 N  N   . VAL   B 2 397 ? 154.429 164.874 198.267 1.00 68.64  ? 1158 VAL   R N   1 
ATOM   3778 C  CA  . VAL   B 2 397 ? 153.881 164.610 199.589 1.00 68.64  ? 1158 VAL   R CA  1 
ATOM   3779 C  C   . VAL   B 2 397 ? 153.592 163.119 199.707 1.00 68.64  ? 1158 VAL   R C   1 
ATOM   3780 O  O   . VAL   B 2 397 ? 153.695 162.363 198.742 1.00 68.64  ? 1158 VAL   R O   1 
ATOM   3781 C  CB  . VAL   B 2 397 ? 152.604 165.427 199.873 1.00 68.64  ? 1158 VAL   R CB  1 
ATOM   3782 C  CG1 . VAL   B 2 397 ? 152.831 166.889 199.595 1.00 68.64  ? 1158 VAL   R CG1 1 
ATOM   3783 C  CG2 . VAL   B 2 397 ? 151.438 164.909 199.052 1.00 68.64  ? 1158 VAL   R CG2 1 
ATOM   3784 N  N   . LYS   B 2 398 ? 153.232 162.704 200.916 1.00 74.22  ? 1159 LYS   R N   1 
ATOM   3785 C  CA  . LYS   B 2 398 ? 152.754 161.351 201.137 1.00 74.22  ? 1159 LYS   R CA  1 
ATOM   3786 C  C   . LYS   B 2 398 ? 151.270 161.263 200.805 1.00 74.22  ? 1159 LYS   R C   1 
ATOM   3787 O  O   . LYS   B 2 398 ? 150.539 162.254 200.869 1.00 74.22  ? 1159 LYS   R O   1 
ATOM   3788 C  CB  . LYS   B 2 398 ? 152.996 160.925 202.584 1.00 74.22  ? 1159 LYS   R CB  1 
ATOM   3789 C  CG  . LYS   B 2 398 ? 154.337 161.370 203.142 1.00 74.22  ? 1159 LYS   R CG  1 
ATOM   3790 C  CD  . LYS   B 2 398 ? 154.375 161.239 204.657 1.00 74.22  ? 1159 LYS   R CD  1 
ATOM   3791 C  CE  . LYS   B 2 398 ? 155.776 160.923 205.150 1.00 74.22  ? 1159 LYS   R CE  1 
ATOM   3792 N  NZ  . LYS   B 2 398 ? 156.642 162.133 205.173 1.00 74.22  ? 1159 LYS   R NZ  1 
ATOM   3793 N  N   . ALA   B 2 399 ? 150.828 160.061 200.446 1.00 72.90  ? 1160 ALA   R N   1 
ATOM   3794 C  CA  . ALA   B 2 399 ? 149.446 159.855 200.037 1.00 72.90  ? 1160 ALA   R CA  1 
ATOM   3795 C  C   . ALA   B 2 399 ? 148.521 159.876 201.246 1.00 72.90  ? 1160 ALA   R C   1 
ATOM   3796 O  O   . ALA   B 2 399 ? 148.768 159.186 202.240 1.00 72.90  ? 1160 ALA   R O   1 
ATOM   3797 C  CB  . ALA   B 2 399 ? 149.302 158.532 199.289 1.00 72.90  ? 1160 ALA   R CB  1 
ATOM   3798 N  N   . GLY   B 2 400 ? 147.452 160.662 201.152 1.00 74.53  ? 1161 GLY   R N   1 
ATOM   3799 C  CA  . GLY   B 2 400 ? 146.451 160.731 202.204 1.00 74.53  ? 1161 GLY   R CA  1 
ATOM   3800 C  C   . GLY   B 2 400 ? 146.943 161.287 203.522 1.00 74.53  ? 1161 GLY   R C   1 
ATOM   3801 O  O   . GLY   B 2 400 ? 146.560 160.780 204.584 1.00 74.53  ? 1161 GLY   R O   1 
ATOM   3802 N  N   . ASP   B 2 401 ? 147.786 162.319 203.485 1.00 78.37  ? 1162 ASP   R N   1 
ATOM   3803 C  CA  . ASP   B 2 401 ? 148.368 162.915 204.686 1.00 78.37  ? 1162 ASP   R CA  1 
ATOM   3804 C  C   . ASP   B 2 401 ? 148.032 164.400 204.721 1.00 78.37  ? 1162 ASP   R C   1 
ATOM   3805 O  O   . ASP   B 2 401 ? 148.726 165.214 204.091 1.00 78.37  ? 1162 ASP   R O   1 
ATOM   3806 C  CB  . ASP   B 2 401 ? 149.877 162.692 204.728 1.00 78.37  ? 1162 ASP   R CB  1 
ATOM   3807 C  CG  . ASP   B 2 401 ? 150.437 162.752 206.133 1.00 78.37  ? 1162 ASP   R CG  1 
ATOM   3808 O  OD1 . ASP   B 2 401 ? 149.698 163.157 207.055 1.00 78.37  ? 1162 ASP   R OD1 1 
ATOM   3809 O  OD2 . ASP   B 2 401 ? 151.619 162.394 206.315 1.00 78.37  ? 1162 ASP   R OD2 1 
ATOM   3810 N  N   . PRO   B 2 402 ? 146.963 164.793 205.423 1.00 74.30  ? 1163 PRO   R N   1 
ATOM   3811 C  CA  . PRO   B 2 402 ? 146.659 166.229 205.561 1.00 74.30  ? 1163 PRO   R CA  1 
ATOM   3812 C  C   . PRO   B 2 402 ? 147.743 167.019 206.271 1.00 74.30  ? 1163 PRO   R C   1 
ATOM   3813 O  O   . PRO   B 2 402 ? 147.951 168.193 205.943 1.00 74.30  ? 1163 PRO   R O   1 
ATOM   3814 C  CB  . PRO   B 2 402 ? 145.347 166.233 206.358 1.00 74.30  ? 1163 PRO   R CB  1 
ATOM   3815 C  CG  . PRO   B 2 402 ? 144.769 164.870 206.163 1.00 74.30  ? 1163 PRO   R CG  1 
ATOM   3816 C  CD  . PRO   B 2 402 ? 145.937 163.948 206.053 1.00 74.30  ? 1163 PRO   R CD  1 
ATOM   3817 N  N   . GLY   B 2 403 ? 148.438 166.416 207.237 1.00 79.55  ? 1164 GLY   R N   1 
ATOM   3818 C  CA  . GLY   B 2 403 ? 149.536 167.113 207.888 1.00 79.55  ? 1164 GLY   R CA  1 
ATOM   3819 C  C   . GLY   B 2 403 ? 150.712 167.360 206.961 1.00 79.55  ? 1164 GLY   R C   1 
ATOM   3820 O  O   . GLY   B 2 403 ? 151.284 168.454 206.945 1.00 79.55  ? 1164 GLY   R O   1 
ATOM   3821 N  N   . GLU   B 2 404 ? 151.089 166.347 206.177 1.00 77.62  ? 1165 GLU   R N   1 
ATOM   3822 C  CA  . GLU   B 2 404 ? 152.195 166.513 205.241 1.00 77.62  ? 1165 GLU   R CA  1 
ATOM   3823 C  C   . GLU   B 2 404 ? 151.819 167.459 204.109 1.00 77.62  ? 1165 GLU   R C   1 
ATOM   3824 O  O   . GLU   B 2 404 ? 152.660 168.228 203.629 1.00 77.62  ? 1165 GLU   R O   1 
ATOM   3825 C  CB  . GLU   B 2 404 ? 152.629 165.150 204.694 1.00 77.62  ? 1165 GLU   R CB  1 
ATOM   3826 C  CG  . GLU   B 2 404 ? 153.822 165.089 203.695 1.00 77.62  ? 1165 GLU   R CG  1 
ATOM   3827 C  CD  . GLU   B 2 404 ? 155.174 165.695 204.140 1.00 77.62  ? 1165 GLU   R CD  1 
ATOM   3828 O  OE1 . GLU   B 2 404 ? 155.273 166.532 205.064 1.00 77.62  ? 1165 GLU   R OE1 1 
ATOM   3829 O  OE2 . GLU   B 2 404 ? 156.188 165.300 203.526 1.00 77.62  ? 1165 GLU   R OE2 1 
ATOM   3830 N  N   . LEU   B 2 405 ? 150.554 167.426 203.683 1.00 74.06  ? 1166 LEU   R N   1 
ATOM   3831 C  CA  . LEU   B 2 405 ? 150.073 168.397 202.706 1.00 74.06  ? 1166 LEU   R CA  1 
ATOM   3832 C  C   . LEU   B 2 405 ? 150.113 169.809 203.271 1.00 74.06  ? 1166 LEU   R C   1 
ATOM   3833 O  O   . LEU   B 2 405 ? 150.456 170.758 202.559 1.00 74.06  ? 1166 LEU   R O   1 
ATOM   3834 C  CB  . LEU   B 2 405 ? 148.657 168.038 202.260 1.00 74.06  ? 1166 LEU   R CB  1 
ATOM   3835 C  CG  . LEU   B 2 405 ? 148.118 168.796 201.046 1.00 74.06  ? 1166 LEU   R CG  1 
ATOM   3836 C  CD1 . LEU   B 2 405 ? 149.022 168.600 199.846 1.00 74.06  ? 1166 LEU   R CD1 1 
ATOM   3837 C  CD2 . LEU   B 2 405 ? 146.708 168.353 200.728 1.00 74.06  ? 1166 LEU   R CD2 1 
ATOM   3838 N  N   . ALA   B 2 406 ? 149.772 169.963 204.553 1.00 75.78  ? 1167 ALA   R N   1 
ATOM   3839 C  CA  . ALA   B 2 406 ? 149.858 171.265 205.208 1.00 75.78  ? 1167 ALA   R CA  1 
ATOM   3840 C  C   . ALA   B 2 406 ? 151.295 171.766 205.268 1.00 75.78  ? 1167 ALA   R C   1 
ATOM   3841 O  O   . ALA   B 2 406 ? 151.564 172.944 204.997 1.00 75.78  ? 1167 ALA   R O   1 
ATOM   3842 C  CB  . ALA   B 2 406 ? 149.273 171.170 206.616 1.00 75.78  ? 1167 ALA   R CB  1 
ATOM   3843 N  N   . ASN   B 2 407 ? 152.230 170.882 205.622 1.00 77.93  ? 1168 ASN   R N   1 
ATOM   3844 C  CA  . ASN   B 2 407 ? 153.636 171.267 205.685 1.00 77.93  ? 1168 ASN   R CA  1 
ATOM   3845 C  C   . ASN   B 2 407 ? 154.170 171.647 204.310 1.00 77.93  ? 1168 ASN   R C   1 
ATOM   3846 O  O   . ASN   B 2 407 ? 154.886 172.646 204.166 1.00 77.93  ? 1168 ASN   R O   1 
ATOM   3847 C  CB  . ASN   B 2 407 ? 154.463 170.136 206.295 1.00 77.93  ? 1168 ASN   R CB  1 
ATOM   3848 C  CG  . ASN   B 2 407 ? 154.263 170.011 207.794 1.00 77.93  ? 1168 ASN   R CG  1 
ATOM   3849 O  OD1 . ASN   B 2 407 ? 153.773 168.996 208.286 1.00 77.93  ? 1168 ASN   R OD1 1 
ATOM   3850 N  ND2 . ASN   B 2 407 ? 154.653 171.045 208.528 1.00 77.93  ? 1168 ASN   R ND2 1 
ATOM   3851 N  N   . ALA   B 2 408 ? 153.806 170.880 203.280 1.00 76.12  ? 1169 ALA   R N   1 
ATOM   3852 C  CA  . ALA   B 2 408 ? 154.244 171.208 201.928 1.00 76.12  ? 1169 ALA   R CA  1 
ATOM   3853 C  C   . ALA   B 2 408 ? 153.613 172.495 201.422 1.00 76.12  ? 1169 ALA   R C   1 
ATOM   3854 O  O   . ALA   B 2 408 ? 154.271 173.262 200.714 1.00 76.12  ? 1169 ALA   R O   1 
ATOM   3855 C  CB  . ALA   B 2 408 ? 153.925 170.063 200.976 1.00 76.12  ? 1169 ALA   R CB  1 
ATOM   3856 N  N   . ILE   B 2 409 ? 152.357 172.762 201.778 1.00 72.85  ? 1170 ILE   R N   1 
ATOM   3857 C  CA  . ILE   B 2 409 ? 151.714 173.974 201.291 1.00 72.85  ? 1170 ILE   R CA  1 
ATOM   3858 C  C   . ILE   B 2 409 ? 152.246 175.214 202.017 1.00 72.85  ? 1170 ILE   R C   1 
ATOM   3859 O  O   . ILE   B 2 409 ? 152.380 176.280 201.403 1.00 72.85  ? 1170 ILE   R O   1 
ATOM   3860 C  CB  . ILE   B 2 409 ? 150.178 173.822 201.367 1.00 72.85  ? 1170 ILE   R CB  1 
ATOM   3861 C  CG1 . ILE   B 2 409 ? 149.498 174.653 200.284 1.00 72.85  ? 1170 ILE   R CG1 1 
ATOM   3862 C  CG2 . ILE   B 2 409 ? 149.607 174.176 202.726 1.00 72.85  ? 1170 ILE   R CG2 1 
ATOM   3863 C  CD1 . ILE   B 2 409 ? 148.073 174.249 200.041 1.00 72.85  ? 1170 ILE   R CD1 1 
ATOM   3864 N  N   . LEU   B 2 410 ? 152.637 175.099 203.293 1.00 78.17  ? 1171 LEU   R N   1 
ATOM   3865 C  CA  . LEU   B 2 410 ? 153.278 176.246 203.934 1.00 78.17  ? 1171 LEU   R CA  1 
ATOM   3866 C  C   . LEU   B 2 410 ? 154.710 176.427 203.441 1.00 78.17  ? 1171 LEU   R C   1 
ATOM   3867 O  O   . LEU   B 2 410 ? 155.189 177.565 203.340 1.00 78.17  ? 1171 LEU   R O   1 
ATOM   3868 C  CB  . LEU   B 2 410 ? 153.232 176.120 205.461 1.00 78.17  ? 1171 LEU   R CB  1 
ATOM   3869 C  CG  . LEU   B 2 410 ? 153.944 174.999 206.223 1.00 78.17  ? 1171 LEU   R CG  1 
ATOM   3870 C  CD1 . LEU   B 2 410 ? 155.325 175.424 206.701 1.00 78.17  ? 1171 LEU   R CD1 1 
ATOM   3871 C  CD2 . LEU   B 2 410 ? 153.095 174.559 207.405 1.00 78.17  ? 1171 LEU   R CD2 1 
ATOM   3872 N  N   . LYS   B 2 411 ? 155.396 175.329 203.107 1.00 78.06  ? 1172 LYS   R N   1 
ATOM   3873 C  CA  . LYS   B 2 411 ? 156.713 175.439 202.488 1.00 78.06  ? 1172 LYS   R CA  1 
ATOM   3874 C  C   . LYS   B 2 411 ? 156.624 176.107 201.121 1.00 78.06  ? 1172 LYS   R C   1 
ATOM   3875 O  O   . LYS   B 2 411 ? 157.480 176.925 200.764 1.00 78.06  ? 1172 LYS   R O   1 
ATOM   3876 C  CB  . LYS   B 2 411 ? 157.348 174.055 202.371 1.00 78.06  ? 1172 LYS   R CB  1 
ATOM   3877 C  CG  . LYS   B 2 411 ? 158.787 174.065 201.897 1.00 78.06  ? 1172 LYS   R CG  1 
ATOM   3878 C  CD  . LYS   B 2 411 ? 159.147 172.753 201.217 1.00 78.06  ? 1172 LYS   R CD  1 
ATOM   3879 C  CE  . LYS   B 2 411 ? 158.859 171.561 202.118 1.00 78.06  ? 1172 LYS   R CE  1 
ATOM   3880 N  NZ  . LYS   B 2 411 ? 158.760 170.294 201.345 1.00 78.06  ? 1172 LYS   R NZ  1 
ATOM   3881 N  N   . ALA   B 2 412 ? 155.589 175.778 200.347 1.00 78.46  ? 1173 ALA   R N   1 
ATOM   3882 C  CA  . ALA   B 2 412 ? 155.385 176.424 199.056 1.00 78.46  ? 1173 ALA   R CA  1 
ATOM   3883 C  C   . ALA   B 2 412 ? 155.022 177.892 199.224 1.00 78.46  ? 1173 ALA   R C   1 
ATOM   3884 O  O   . ALA   B 2 412 ? 155.422 178.731 198.409 1.00 78.46  ? 1173 ALA   R O   1 
ATOM   3885 C  CB  . ALA   B 2 412 ? 154.302 175.691 198.269 1.00 78.46  ? 1173 ALA   R CB  1 
ATOM   3886 N  N   . LEU   B 2 413 ? 154.263 178.219 200.274 1.00 79.72  ? 1174 LEU   R N   1 
ATOM   3887 C  CA  . LEU   B 2 413 ? 153.971 179.619 200.573 1.00 79.72  ? 1174 LEU   R CA  1 
ATOM   3888 C  C   . LEU   B 2 413 ? 155.243 180.394 200.898 1.00 79.72  ? 1174 LEU   R C   1 
ATOM   3889 O  O   . LEU   B 2 413 ? 155.412 181.536 200.457 1.00 79.72  ? 1174 LEU   R O   1 
ATOM   3890 C  CB  . LEU   B 2 413 ? 152.982 179.709 201.732 1.00 79.72  ? 1174 LEU   R CB  1 
ATOM   3891 C  CG  . LEU   B 2 413 ? 152.537 181.121 202.111 1.00 79.72  ? 1174 LEU   R CG  1 
ATOM   3892 C  CD1 . LEU   B 2 413 ? 151.803 181.774 200.960 1.00 79.72  ? 1174 LEU   R CD1 1 
ATOM   3893 C  CD2 . LEU   B 2 413 ? 151.665 181.082 203.348 1.00 79.72  ? 1174 LEU   R CD2 1 
ATOM   3894 N  N   . GLU   B 2 414 ? 156.142 179.788 201.677 1.00 81.28  ? 1175 GLU   R N   1 
ATOM   3895 C  CA  . GLU   B 2 414 ? 157.429 180.418 201.962 1.00 81.28  ? 1175 GLU   R CA  1 
ATOM   3896 C  C   . GLU   B 2 414 ? 158.267 180.564 200.695 1.00 81.28  ? 1175 GLU   R C   1 
ATOM   3897 O  O   . GLU   B 2 414 ? 158.910 181.599 200.480 1.00 81.28  ? 1175 GLU   R O   1 
ATOM   3898 C  CB  . GLU   B 2 414 ? 158.177 179.610 203.025 1.00 81.28  ? 1175 GLU   R CB  1 
ATOM   3899 C  CG  . GLU   B 2 414 ? 159.692 179.760 203.016 1.00 81.28  ? 1175 GLU   R CG  1 
ATOM   3900 C  CD  . GLU   B 2 414 ? 160.148 181.151 203.407 1.00 81.28  ? 1175 GLU   R CD  1 
ATOM   3901 O  OE1 . GLU   B 2 414 ? 159.451 181.806 204.208 1.00 81.28  ? 1175 GLU   R OE1 1 
ATOM   3902 O  OE2 . GLU   B 2 414 ? 161.210 181.589 202.918 1.00 81.28  ? 1175 GLU   R OE2 1 
ATOM   3903 N  N   . LEU   B 2 415 ? 158.256 179.539 199.838 1.00 81.76  ? 1176 LEU   R N   1 
ATOM   3904 C  CA  . LEU   B 2 415 ? 159.045 179.562 198.609 1.00 81.76  ? 1176 LEU   R CA  1 
ATOM   3905 C  C   . LEU   B 2 415 ? 158.527 180.597 197.617 1.00 81.76  ? 1176 LEU   R C   1 
ATOM   3906 O  O   . LEU   B 2 415 ? 159.312 181.165 196.850 1.00 81.76  ? 1176 LEU   R O   1 
ATOM   3907 C  CB  . LEU   B 2 415 ? 159.049 178.168 197.979 1.00 81.76  ? 1176 LEU   R CB  1 
ATOM   3908 C  CG  . LEU   B 2 415 ? 159.793 177.958 196.662 1.00 81.76  ? 1176 LEU   R CG  1 
ATOM   3909 C  CD1 . LEU   B 2 415 ? 161.267 177.701 196.924 1.00 81.76  ? 1176 LEU   R CD1 1 
ATOM   3910 C  CD2 . LEU   B 2 415 ? 159.172 176.815 195.879 1.00 81.76  ? 1176 LEU   R CD2 1 
ATOM   3911 N  N   . SER   B 2 416 ? 157.220 180.869 197.627 1.00 81.33  ? 1177 SER   R N   1 
ATOM   3912 C  CA  . SER   B 2 416 ? 156.640 181.832 196.696 1.00 81.33  ? 1177 SER   R CA  1 
ATOM   3913 C  C   . SER   B 2 416 ? 157.011 183.277 197.009 1.00 81.33  ? 1177 SER   R C   1 
ATOM   3914 O  O   . SER   B 2 416 ? 156.700 184.159 196.202 1.00 81.33  ? 1177 SER   R O   1 
ATOM   3915 C  CB  . SER   B 2 416 ? 155.118 181.694 196.679 1.00 81.33  ? 1177 SER   R CB  1 
ATOM   3916 O  OG  . SER   B 2 416 ? 154.531 182.664 195.830 1.00 81.33  ? 1177 SER   R OG  1 
ATOM   3917 N  N   . ARG   B 2 417 ? 157.642 183.545 198.156 1.00 83.97  ? 1178 ARG   R N   1 
ATOM   3918 C  CA  . ARG   B 2 417 ? 158.061 184.907 198.473 1.00 83.97  ? 1178 ARG   R CA  1 
ATOM   3919 C  C   . ARG   B 2 417 ? 159.202 185.372 197.578 1.00 83.97  ? 1178 ARG   R C   1 
ATOM   3920 O  O   . ARG   B 2 417 ? 159.286 186.562 197.254 1.00 83.97  ? 1178 ARG   R O   1 
ATOM   3921 C  CB  . ARG   B 2 417 ? 158.463 185.005 199.944 1.00 83.97  ? 1178 ARG   R CB  1 
ATOM   3922 C  CG  . ARG   B 2 417 ? 157.509 185.844 200.779 1.00 83.97  ? 1178 ARG   R CG  1 
ATOM   3923 C  CD  . ARG   B 2 417 ? 157.791 185.709 202.267 1.00 83.97  ? 1178 ARG   R CD  1 
ATOM   3924 N  NE  . ARG   B 2 417 ? 157.343 184.427 202.797 1.00 83.97  ? 1178 ARG   R NE  1 
ATOM   3925 C  CZ  . ARG   B 2 417 ? 156.094 184.156 203.151 1.00 83.97  ? 1178 ARG   R CZ  1 
ATOM   3926 N  NH1 . ARG   B 2 417 ? 155.132 185.058 203.041 1.00 83.97  ? 1178 ARG   R NH1 1 
ATOM   3927 N  NH2 . ARG   B 2 417 ? 155.802 182.950 203.630 1.00 83.97  ? 1178 ARG   R NH2 1 
ATOM   3928 N  N   . SER   B 2 418 ? 160.080 184.462 197.170 1.00 87.17  ? 1179 SER   R N   1 
ATOM   3929 C  CA  . SER   B 2 418 ? 161.156 184.789 196.244 1.00 87.17  ? 1179 SER   R CA  1 
ATOM   3930 C  C   . SER   B 2 418 ? 160.631 184.704 194.811 1.00 87.17  ? 1179 SER   R C   1 
ATOM   3931 O  O   . SER   B 2 418 ? 159.425 184.598 194.571 1.00 87.17  ? 1179 SER   R O   1 
ATOM   3932 C  CB  . SER   B 2 418 ? 162.349 183.866 196.475 1.00 87.17  ? 1179 SER   R CB  1 
ATOM   3933 O  OG  . SER   B 2 418 ? 162.051 182.538 196.081 1.00 87.17  ? 1179 SER   R OG  1 
ATOM   3934 N  N   . ASP   B 2 419 ? 161.531 184.759 193.834 1.00 85.47  ? 1180 ASP   R N   1 
ATOM   3935 C  CA  . ASP   B 2 419 ? 161.113 184.575 192.454 1.00 85.47  ? 1180 ASP   R CA  1 
ATOM   3936 C  C   . ASP   B 2 419 ? 160.819 183.102 192.186 1.00 85.47  ? 1180 ASP   R C   1 
ATOM   3937 O  O   . ASP   B 2 419 ? 161.316 182.204 192.870 1.00 85.47  ? 1180 ASP   R O   1 
ATOM   3938 C  CB  . ASP   B 2 419 ? 162.182 185.083 191.487 1.00 85.47  ? 1180 ASP   R CB  1 
ATOM   3939 C  CG  . ASP   B 2 419 ? 163.352 184.135 191.362 1.00 85.47  ? 1180 ASP   R CG  1 
ATOM   3940 O  OD1 . ASP   B 2 419 ? 163.858 183.667 192.405 1.00 85.47  ? 1180 ASP   R OD1 1 
ATOM   3941 O  OD2 . ASP   B 2 419 ? 163.764 183.852 190.218 1.00 85.47  ? 1180 ASP   R OD2 1 
ATOM   3942 N  N   . LEU   B 2 420 ? 159.993 182.858 191.170 1.00 78.22  ? 1181 LEU   R N   1 
ATOM   3943 C  CA  . LEU   B 2 420 ? 159.569 181.507 190.844 1.00 78.22  ? 1181 LEU   R CA  1 
ATOM   3944 C  C   . LEU   B 2 420 ? 159.775 181.134 189.384 1.00 78.22  ? 1181 LEU   R C   1 
ATOM   3945 O  O   . LEU   B 2 420 ? 159.388 180.029 188.993 1.00 78.22  ? 1181 LEU   R O   1 
ATOM   3946 C  CB  . LEU   B 2 420 ? 158.087 181.312 191.198 1.00 78.22  ? 1181 LEU   R CB  1 
ATOM   3947 C  CG  . LEU   B 2 420 ? 157.767 180.847 192.618 1.00 78.22  ? 1181 LEU   R CG  1 
ATOM   3948 C  CD1 . LEU   B 2 420 ? 156.279 180.622 192.773 1.00 78.22  ? 1181 LEU   R CD1 1 
ATOM   3949 C  CD2 . LEU   B 2 420 ? 158.528 179.588 192.956 1.00 78.22  ? 1181 LEU   R CD2 1 
ATOM   3950 N  N   . SER   B 2 421 ? 160.376 182.012 188.575 1.00 78.25  ? 1182 SER   R N   1 
ATOM   3951 C  CA  . SER   B 2 421 ? 160.475 181.763 187.139 1.00 78.25  ? 1182 SER   R CA  1 
ATOM   3952 C  C   . SER   B 2 421 ? 161.398 180.594 186.819 1.00 78.25  ? 1182 SER   R C   1 
ATOM   3953 O  O   . SER   B 2 421 ? 161.222 179.937 185.785 1.00 78.25  ? 1182 SER   R O   1 
ATOM   3954 C  CB  . SER   B 2 421 ? 160.951 183.026 186.425 1.00 78.25  ? 1182 SER   R CB  1 
ATOM   3955 O  OG  . SER   B 2 421 ? 160.001 184.068 186.559 1.00 78.25  ? 1182 SER   R OG  1 
ATOM   3956 N  N   . LYS   B 2 422 ? 162.383 180.327 187.680 1.00 79.97  ? 1183 LYS   R N   1 
ATOM   3957 C  CA  . LYS   B 2 422 ? 163.245 179.167 187.481 1.00 79.97  ? 1183 LYS   R CA  1 
ATOM   3958 C  C   . LYS   B 2 422 ? 162.454 177.871 187.582 1.00 79.97  ? 1183 LYS   R C   1 
ATOM   3959 O  O   . LYS   B 2 422 ? 162.623 176.966 186.756 1.00 79.97  ? 1183 LYS   R O   1 
ATOM   3960 C  CB  . LYS   B 2 422 ? 164.387 179.180 188.496 1.00 79.97  ? 1183 LYS   R CB  1 
ATOM   3961 C  CG  . LYS   B 2 422 ? 165.134 180.498 188.566 1.00 79.97  ? 1183 LYS   R CG  1 
ATOM   3962 C  CD  . LYS   B 2 422 ? 166.505 180.377 187.925 1.00 79.97  ? 1183 LYS   R CD  1 
ATOM   3963 C  CE  . LYS   B 2 422 ? 167.241 181.706 187.933 1.00 79.97  ? 1183 LYS   R CE  1 
ATOM   3964 N  NZ  . LYS   B 2 422 ? 167.337 182.282 189.302 1.00 79.97  ? 1183 LYS   R NZ  1 
ATOM   3965 N  N   . PHE   B 2 423 ? 161.564 177.772 188.572 1.00 76.43  ? 1184 PHE   R N   1 
ATOM   3966 C  CA  . PHE   B 2 423 ? 160.712 176.593 188.677 1.00 76.43  ? 1184 PHE   R CA  1 
ATOM   3967 C  C   . PHE   B 2 423 ? 159.739 176.486 187.510 1.00 76.43  ? 1184 PHE   R C   1 
ATOM   3968 O  O   . PHE   B 2 423 ? 159.472 175.377 187.041 1.00 76.43  ? 1184 PHE   R O   1 
ATOM   3969 C  CB  . PHE   B 2 423 ? 159.958 176.600 190.003 1.00 76.43  ? 1184 PHE   R CB  1 
ATOM   3970 C  CG  . PHE   B 2 423 ? 160.840 176.425 191.203 1.00 76.43  ? 1184 PHE   R CG  1 
ATOM   3971 C  CD1 . PHE   B 2 423 ? 161.270 175.165 191.577 1.00 76.43  ? 1184 PHE   R CD1 1 
ATOM   3972 C  CD2 . PHE   B 2 423 ? 161.245 177.516 191.949 1.00 76.43  ? 1184 PHE   R CD2 1 
ATOM   3973 C  CE1 . PHE   B 2 423 ? 162.081 174.993 192.679 1.00 76.43  ? 1184 PHE   R CE1 1 
ATOM   3974 C  CE2 . PHE   B 2 423 ? 162.056 177.353 193.054 1.00 76.43  ? 1184 PHE   R CE2 1 
ATOM   3975 C  CZ  . PHE   B 2 423 ? 162.476 176.088 193.419 1.00 76.43  ? 1184 PHE   R CZ  1 
ATOM   3976 N  N   . ARG   B 2 424 ? 159.210 177.613 187.024 1.00 71.60  ? 1185 ARG   R N   1 
ATOM   3977 C  CA  . ARG   B 2 424 ? 158.306 177.568 185.877 1.00 71.60  ? 1185 ARG   R CA  1 
ATOM   3978 C  C   . ARG   B 2 424 ? 159.019 177.080 184.621 1.00 71.60  ? 1185 ARG   R C   1 
ATOM   3979 O  O   . ARG   B 2 424 ? 158.482 176.245 183.881 1.00 71.60  ? 1185 ARG   R O   1 
ATOM   3980 C  CB  . ARG   B 2 424 ? 157.685 178.941 185.634 1.00 71.60  ? 1185 ARG   R CB  1 
ATOM   3981 C  CG  . ARG   B 2 424 ? 157.019 179.540 186.849 1.00 71.60  ? 1185 ARG   R CG  1 
ATOM   3982 C  CD  . ARG   B 2 424 ? 155.543 179.211 186.890 1.00 71.60  ? 1185 ARG   R CD  1 
ATOM   3983 N  NE  . ARG   B 2 424 ? 155.013 179.245 188.248 1.00 71.60  ? 1185 ARG   R NE  1 
ATOM   3984 C  CZ  . ARG   B 2 424 ? 154.644 180.349 188.882 1.00 71.60  ? 1185 ARG   R CZ  1 
ATOM   3985 N  NH1 . ARG   B 2 424 ? 154.725 181.537 188.307 1.00 71.60  ? 1185 ARG   R NH1 1 
ATOM   3986 N  NH2 . ARG   B 2 424 ? 154.176 180.257 190.123 1.00 71.60  ? 1185 ARG   R NH2 1 
ATOM   3987 N  N   . GLU   B 2 425 ? 160.237 177.569 184.371 1.00 77.45  ? 1186 GLU   R N   1 
ATOM   3988 C  CA  . GLU   B 2 425 ? 160.952 177.112 183.184 1.00 77.45  ? 1186 GLU   R CA  1 
ATOM   3989 C  C   . GLU   B 2 425 ? 161.416 175.668 183.335 1.00 77.45  ? 1186 GLU   R C   1 
ATOM   3990 O  O   . GLU   B 2 425 ? 161.429 174.923 182.349 1.00 77.45  ? 1186 GLU   R O   1 
ATOM   3991 C  CB  . GLU   B 2 425 ? 162.120 178.051 182.859 1.00 77.45  ? 1186 GLU   R CB  1 
ATOM   3992 C  CG  . GLU   B 2 425 ? 163.328 177.969 183.776 1.00 77.45  ? 1186 GLU   R CG  1 
ATOM   3993 C  CD  . GLU   B 2 425 ? 164.278 179.139 183.604 1.00 77.45  ? 1186 GLU   R CD  1 
ATOM   3994 O  OE1 . GLU   B 2 425 ? 163.940 180.081 182.858 1.00 77.45  ? 1186 GLU   R OE1 1 
ATOM   3995 O  OE2 . GLU   B 2 425 ? 165.365 179.113 184.216 1.00 77.45  ? 1186 GLU   R OE2 1 
ATOM   3996 N  N   . ASN   B 2 426 ? 161.743 175.236 184.557 1.00 74.03  ? 1187 ASN   R N   1 
ATOM   3997 C  CA  . ASN   B 2 426 ? 162.113 173.840 184.764 1.00 74.03  ? 1187 ASN   R CA  1 
ATOM   3998 C  C   . ASN   B 2 426 ? 160.922 172.910 184.562 1.00 74.03  ? 1187 ASN   R C   1 
ATOM   3999 O  O   . ASN   B 2 426 ? 161.064 171.838 183.963 1.00 74.03  ? 1187 ASN   R O   1 
ATOM   4000 C  CB  . ASN   B 2 426 ? 162.712 173.662 186.156 1.00 74.03  ? 1187 ASN   R CB  1 
ATOM   4001 C  CG  . ASN   B 2 426 ? 164.076 174.301 186.282 1.00 74.03  ? 1187 ASN   R CG  1 
ATOM   4002 O  OD1 . ASN   B 2 426 ? 164.884 174.252 185.356 1.00 74.03  ? 1187 ASN   R OD1 1 
ATOM   4003 N  ND2 . ASN   B 2 426 ? 164.335 174.921 187.428 1.00 74.03  ? 1187 ASN   R ND2 1 
ATOM   4004 N  N   . CYS   B 2 427 ? 159.739 173.307 185.040 1.00 71.38  ? 1188 CYS   R N   1 
ATOM   4005 C  CA  . CYS   B 2 427 ? 158.542 172.501 184.820 1.00 71.38  ? 1188 CYS   R CA  1 
ATOM   4006 C  C   . CYS   B 2 427 ? 158.148 172.471 183.348 1.00 71.38  ? 1188 CYS   R C   1 
ATOM   4007 O  O   . CYS   B 2 427 ? 157.700 171.434 182.846 1.00 71.38  ? 1188 CYS   R O   1 
ATOM   4008 C  CB  . CYS   B 2 427 ? 157.386 173.018 185.674 1.00 71.38  ? 1188 CYS   R CB  1 
ATOM   4009 S  SG  . CYS   B 2 427 ? 157.623 172.805 187.446 1.00 71.38  ? 1188 CYS   R SG  1 
ATOM   4010 N  N   . LYS   B 2 428 ? 158.300 173.594 182.641 1.00 66.46  ? 1189 LYS   R N   1 
ATOM   4011 C  CA  . LYS   B 2 428 ? 158.011 173.602 181.211 1.00 66.46  ? 1189 LYS   R CA  1 
ATOM   4012 C  C   . LYS   B 2 428 ? 158.975 172.704 180.444 1.00 66.46  ? 1189 LYS   R C   1 
ATOM   4013 O  O   . LYS   B 2 428 ? 158.561 171.976 179.533 1.00 66.46  ? 1189 LYS   R O   1 
ATOM   4014 C  CB  . LYS   B 2 428 ? 158.062 175.028 180.675 1.00 66.46  ? 1189 LYS   R CB  1 
ATOM   4015 C  CG  . LYS   B 2 428 ? 156.746 175.768 180.774 1.00 66.46  ? 1189 LYS   R CG  1 
ATOM   4016 C  CD  . LYS   B 2 428 ? 156.928 177.228 180.418 1.00 66.46  ? 1189 LYS   R CD  1 
ATOM   4017 C  CE  . LYS   B 2 428 ? 155.598 177.943 180.331 1.00 66.46  ? 1189 LYS   R CE  1 
ATOM   4018 N  NZ  . LYS   B 2 428 ? 154.858 177.597 179.088 1.00 66.46  ? 1189 LYS   R NZ  1 
ATOM   4019 N  N   . LYS   B 2 429 ? 160.260 172.731 180.808 1.00 68.42  ? 1190 LYS   R N   1 
ATOM   4020 C  CA  . LYS   B 2 429 ? 161.236 171.868 180.151 1.00 68.42  ? 1190 LYS   R CA  1 
ATOM   4021 C  C   . LYS   B 2 429 ? 160.988 170.399 180.470 1.00 68.42  ? 1190 LYS   R C   1 
ATOM   4022 O  O   . LYS   B 2 429 ? 161.224 169.529 179.625 1.00 68.42  ? 1190 LYS   R O   1 
ATOM   4023 C  CB  . LYS   B 2 429 ? 162.649 172.275 180.562 1.00 68.42  ? 1190 LYS   R CB  1 
ATOM   4024 C  CG  . LYS   B 2 429 ? 163.332 173.200 179.576 1.00 68.42  ? 1190 LYS   R CG  1 
ATOM   4025 C  CD  . LYS   B 2 429 ? 164.814 173.319 179.875 1.00 68.42  ? 1190 LYS   R CD  1 
ATOM   4026 C  CE  . LYS   B 2 429 ? 165.093 174.476 180.819 1.00 68.42  ? 1190 LYS   R CE  1 
ATOM   4027 N  NZ  . LYS   B 2 429 ? 166.416 175.099 180.548 1.00 68.42  ? 1190 LYS   R NZ  1 
ATOM   4028 N  N   . ARG   B 2 430 ? 160.526 170.102 181.685 1.00 64.51  ? 1191 ARG   R N   1 
ATOM   4029 C  CA  . ARG   B 2 430 ? 160.238 168.717 182.040 1.00 64.51  ? 1191 ARG   R CA  1 
ATOM   4030 C  C   . ARG   B 2 430 ? 158.991 168.204 181.330 1.00 64.51  ? 1191 ARG   R C   1 
ATOM   4031 O  O   . ARG   B 2 430 ? 158.984 167.081 180.814 1.00 64.51  ? 1191 ARG   R O   1 
ATOM   4032 C  CB  . ARG   B 2 430 ? 160.082 168.586 183.552 1.00 64.51  ? 1191 ARG   R CB  1 
ATOM   4033 C  CG  . ARG   B 2 430 ? 159.711 167.193 184.013 1.00 64.51  ? 1191 ARG   R CG  1 
ATOM   4034 C  CD  . ARG   B 2 430 ? 160.869 166.233 183.862 1.00 64.51  ? 1191 ARG   R CD  1 
ATOM   4035 N  NE  . ARG   B 2 430 ? 160.572 164.938 184.458 1.00 64.51  ? 1191 ARG   R NE  1 
ATOM   4036 C  CZ  . ARG   B 2 430 ? 161.119 163.794 184.071 1.00 64.51  ? 1191 ARG   R CZ  1 
ATOM   4037 N  NH1 . ARG   B 2 430 ? 162.002 163.748 183.088 1.00 64.51  ? 1191 ARG   R NH1 1 
ATOM   4038 N  NH2 . ARG   B 2 430 ? 160.768 162.667 184.684 1.00 64.51  ? 1191 ARG   R NH2 1 
ATOM   4039 N  N   . ALA   B 2 431 ? 157.928 169.007 181.291 1.00 61.92  ? 1192 ALA   R N   1 
ATOM   4040 C  CA  . ALA   B 2 431 ? 156.674 168.544 180.714 1.00 61.92  ? 1192 ALA   R CA  1 
ATOM   4041 C  C   . ALA   B 2 431 ? 156.697 168.540 179.195 1.00 61.92  ? 1192 ALA   R C   1 
ATOM   4042 O  O   . ALA   B 2 431 ? 156.005 167.725 178.577 1.00 61.92  ? 1192 ALA   R O   1 
ATOM   4043 C  CB  . ALA   B 2 431 ? 155.517 169.404 181.206 1.00 61.92  ? 1192 ALA   R CB  1 
ATOM   4044 N  N   . MET   B 2 432 ? 157.459 169.440 178.572 1.00 65.00  ? 1193 MET   R N   1 
ATOM   4045 C  CA  . MET   B 2 432 ? 157.558 169.415 177.120 1.00 65.00  ? 1193 MET   R CA  1 
ATOM   4046 C  C   . MET   B 2 432 ? 158.363 168.214 176.637 1.00 65.00  ? 1193 MET   R C   1 
ATOM   4047 O  O   . MET   B 2 432 ? 158.187 167.774 175.497 1.00 65.00  ? 1193 MET   R O   1 
ATOM   4048 C  CB  . MET   B 2 432 ? 158.163 170.735 176.629 1.00 65.00  ? 1193 MET   R CB  1 
ATOM   4049 C  CG  . MET   B 2 432 ? 158.213 170.910 175.120 1.00 65.00  ? 1193 MET   R CG  1 
ATOM   4050 S  SD  . MET   B 2 432 ? 156.557 170.943 174.410 1.00 65.00  ? 1193 MET   R SD  1 
ATOM   4051 C  CE  . MET   B 2 432 ? 155.986 172.548 174.954 1.00 65.00  ? 1193 MET   R CE  1 
ATOM   4052 N  N   . SER   B 2 433 ? 159.193 167.640 177.505 1.00 63.65  ? 1194 SER   R N   1 
ATOM   4053 C  CA  . SER   B 2 433 ? 159.978 166.456 177.192 1.00 63.65  ? 1194 SER   R CA  1 
ATOM   4054 C  C   . SER   B 2 433 ? 159.158 165.174 177.195 1.00 63.65  ? 1194 SER   R C   1 
ATOM   4055 O  O   . SER   B 2 433 ? 159.676 164.130 176.790 1.00 63.65  ? 1194 SER   R O   1 
ATOM   4056 C  CB  . SER   B 2 433 ? 161.131 166.321 178.185 1.00 63.65  ? 1194 SER   R CB  1 
ATOM   4057 O  OG  . SER   B 2 433 ? 161.591 164.984 178.242 1.00 63.65  ? 1194 SER   R OG  1 
ATOM   4058 N  N   . PHE   B 2 434 ? 157.909 165.216 177.653 1.00 62.46  ? 1195 PHE   R N   1 
ATOM   4059 C  CA  . PHE   B 2 434 ? 157.035 164.053 177.621 1.00 62.46  ? 1195 PHE   R CA  1 
ATOM   4060 C  C   . PHE   B 2 434 ? 156.212 163.953 176.345 1.00 62.46  ? 1195 PHE   R C   1 
ATOM   4061 O  O   . PHE   B 2 434 ? 155.522 162.948 176.150 1.00 62.46  ? 1195 PHE   R O   1 
ATOM   4062 C  CB  . PHE   B 2 434 ? 156.094 164.064 178.829 1.00 62.46  ? 1195 PHE   R CB  1 
ATOM   4063 C  CG  . PHE   B 2 434 ? 156.685 163.450 180.062 1.00 62.46  ? 1195 PHE   R CG  1 
ATOM   4064 C  CD1 . PHE   B 2 434 ? 156.547 162.096 180.307 1.00 62.46  ? 1195 PHE   R CD1 1 
ATOM   4065 C  CD2 . PHE   B 2 434 ? 157.387 164.222 180.969 1.00 62.46  ? 1195 PHE   R CD2 1 
ATOM   4066 C  CE1 . PHE   B 2 434 ? 157.087 161.525 181.440 1.00 62.46  ? 1195 PHE   R CE1 1 
ATOM   4067 C  CE2 . PHE   B 2 434 ? 157.934 163.656 182.102 1.00 62.46  ? 1195 PHE   R CE2 1 
ATOM   4068 C  CZ  . PHE   B 2 434 ? 157.783 162.305 182.337 1.00 62.46  ? 1195 PHE   R CZ  1 
ATOM   4069 N  N   . SER   B 2 435 ? 156.262 164.961 175.483 1.00 64.87  ? 1196 SER   R N   1 
ATOM   4070 C  CA  . SER   B 2 435 ? 155.561 164.932 174.209 1.00 64.87  ? 1196 SER   R CA  1 
ATOM   4071 C  C   . SER   B 2 435 ? 156.482 164.618 173.039 1.00 64.87  ? 1196 SER   R C   1 
ATOM   4072 O  O   . SER   B 2 435 ? 156.087 164.820 171.887 1.00 64.87  ? 1196 SER   R O   1 
ATOM   4073 C  CB  . SER   B 2 435 ? 154.856 166.268 173.968 1.00 64.87  ? 1196 SER   R CB  1 
ATOM   4074 O  OG  . SER   B 2 435 ? 154.093 166.238 172.775 1.00 64.87  ? 1196 SER   R OG  1 
ATOM   4075 N  N   . ASP   B 2 436 ? 157.701 164.143 173.306 1.00 65.02  ? 333  ASP   R N   1 
ATOM   4076 C  CA  . ASP   B 2 436 ? 158.644 163.863 172.229 1.00 65.02  ? 333  ASP   R CA  1 
ATOM   4077 C  C   . ASP   B 2 436 ? 158.223 162.653 171.399 1.00 65.02  ? 333  ASP   R C   1 
ATOM   4078 O  O   . ASP   B 2 436 ? 158.450 162.619 170.184 1.00 65.02  ? 333  ASP   R O   1 
ATOM   4079 C  CB  . ASP   B 2 436 ? 160.053 163.690 172.805 1.00 65.02  ? 333  ASP   R CB  1 
ATOM   4080 C  CG  . ASP   B 2 436 ? 160.175 162.512 173.770 1.00 65.02  ? 333  ASP   R CG  1 
ATOM   4081 O  OD1 . ASP   B 2 436 ? 159.172 161.822 174.058 1.00 65.02  ? 333  ASP   R OD1 1 
ATOM   4082 O  OD2 . ASP   B 2 436 ? 161.304 162.271 174.245 1.00 65.02  ? 333  ASP   R OD2 1 
ATOM   4083 N  N   . GLN   B 2 437 ? 157.626 161.644 172.041 1.00 61.75  ? 334  GLN   R N   1 
ATOM   4084 C  CA  . GLN   B 2 437 ? 157.141 160.475 171.313 1.00 61.75  ? 334  GLN   R CA  1 
ATOM   4085 C  C   . GLN   B 2 437 ? 155.999 160.841 170.374 1.00 61.75  ? 334  GLN   R C   1 
ATOM   4086 O  O   . GLN   B 2 437 ? 155.908 160.316 169.255 1.00 61.75  ? 334  GLN   R O   1 
ATOM   4087 C  CB  . GLN   B 2 437 ? 156.701 159.392 172.297 1.00 61.75  ? 334  GLN   R CB  1 
ATOM   4088 C  CG  . GLN   B 2 437 ? 156.444 158.015 171.684 1.00 61.75  ? 334  GLN   R CG  1 
ATOM   4089 C  CD  . GLN   B 2 437 ? 157.682 157.369 171.083 1.00 61.75  ? 334  GLN   R CD  1 
ATOM   4090 O  OE1 . GLN   B 2 437 ? 158.079 157.675 169.958 1.00 61.75  ? 334  GLN   R OE1 1 
ATOM   4091 N  NE2 . GLN   B 2 437 ? 158.297 156.465 171.834 1.00 61.75  ? 334  GLN   R NE2 1 
ATOM   4092 N  N   . ALA   B 2 438 ? 155.120 161.743 170.815 1.00 57.24  ? 335  ALA   R N   1 
ATOM   4093 C  CA  . ALA   B 2 438 ? 154.012 162.182 169.975 1.00 57.24  ? 335  ALA   R CA  1 
ATOM   4094 C  C   . ALA   B 2 438 ? 154.512 162.906 168.734 1.00 57.24  ? 335  ALA   R C   1 
ATOM   4095 O  O   . ALA   B 2 438 ? 153.983 162.701 167.638 1.00 57.24  ? 335  ALA   R O   1 
ATOM   4096 C  CB  . ALA   B 2 438 ? 153.071 163.079 170.775 1.00 57.24  ? 335  ALA   R CB  1 
ATOM   4097 N  N   . ARG   B 2 439 ? 155.543 163.743 168.884 1.00 60.22  ? 336  ARG   R N   1 
ATOM   4098 C  CA  . ARG   B 2 439 ? 156.078 164.473 167.738 1.00 60.22  ? 336  ARG   R CA  1 
ATOM   4099 C  C   . ARG   B 2 439 ? 156.727 163.531 166.732 1.00 60.22  ? 336  ARG   R C   1 
ATOM   4100 O  O   . ARG   B 2 439 ? 156.601 163.727 165.517 1.00 60.22  ? 336  ARG   R O   1 
ATOM   4101 C  CB  . ARG   B 2 439 ? 157.076 165.530 168.208 1.00 60.22  ? 336  ARG   R CB  1 
ATOM   4102 C  CG  . ARG   B 2 439 ? 156.447 166.638 169.028 1.00 60.22  ? 336  ARG   R CG  1 
ATOM   4103 C  CD  . ARG   B 2 439 ? 157.416 167.781 169.244 1.00 60.22  ? 336  ARG   R CD  1 
ATOM   4104 N  NE  . ARG   B 2 439 ? 158.399 167.477 170.276 1.00 60.22  ? 336  ARG   R NE  1 
ATOM   4105 C  CZ  . ARG   B 2 439 ? 158.281 167.831 171.547 1.00 60.22  ? 336  ARG   R CZ  1 
ATOM   4106 N  NH1 . ARG   B 2 439 ? 157.215 168.480 171.986 1.00 60.22  ? 336  ARG   R NH1 1 
ATOM   4107 N  NH2 . ARG   B 2 439 ? 159.254 167.523 172.400 1.00 60.22  ? 336  ARG   R NH2 1 
ATOM   4108 N  N   . MET   B 2 440 ? 157.419 162.497 167.215 1.00 59.26  ? 337  MET   R N   1 
ATOM   4109 C  CA  . MET   B 2 440 ? 157.967 161.500 166.304 1.00 59.26  ? 337  MET   R CA  1 
ATOM   4110 C  C   . MET   B 2 440 ? 156.867 160.702 165.615 1.00 59.26  ? 337  MET   R C   1 
ATOM   4111 O  O   . MET   B 2 440 ? 157.025 160.315 164.452 1.00 59.26  ? 337  MET   R O   1 
ATOM   4112 C  CB  . MET   B 2 440 ? 158.928 160.570 167.042 1.00 59.26  ? 337  MET   R CB  1 
ATOM   4113 C  CG  . MET   B 2 440 ? 160.188 161.264 167.529 1.00 59.26  ? 337  MET   R CG  1 
ATOM   4114 S  SD  . MET   B 2 440 ? 161.355 160.155 168.341 1.00 59.26  ? 337  MET   R SD  1 
ATOM   4115 C  CE  . MET   B 2 440 ? 160.539 159.877 169.906 1.00 59.26  ? 337  MET   R CE  1 
ATOM   4116 N  N   . ASP   B 2 441 ? 155.750 160.457 166.303 1.00 55.38  ? 338  ASP   R N   1 
ATOM   4117 C  CA  . ASP   B 2 441 ? 154.616 159.811 165.648 1.00 55.38  ? 338  ASP   R CA  1 
ATOM   4118 C  C   . ASP   B 2 441 ? 154.029 160.692 164.549 1.00 55.38  ? 338  ASP   R C   1 
ATOM   4119 O  O   . ASP   B 2 441 ? 153.654 160.193 163.480 1.00 55.38  ? 338  ASP   R O   1 
ATOM   4120 C  CB  . ASP   B 2 441 ? 153.551 159.456 166.680 1.00 55.38  ? 338  ASP   R CB  1 
ATOM   4121 C  CG  . ASP   B 2 441 ? 153.864 158.172 167.413 1.00 55.38  ? 338  ASP   R CG  1 
ATOM   4122 O  OD1 . ASP   B 2 441 ? 155.042 157.761 167.413 1.00 55.38  ? 338  ASP   R OD1 1 
ATOM   4123 O  OD2 . ASP   B 2 441 ? 152.932 157.571 167.985 1.00 55.38  ? 338  ASP   R OD2 1 
ATOM   4124 N  N   . ILE   B 2 442 ? 153.947 162.002 164.793 1.00 50.93  ? 339  ILE   R N   1 
ATOM   4125 C  CA  . ILE   B 2 442 ? 153.483 162.929 163.759 1.00 50.93  ? 339  ILE   R CA  1 
ATOM   4126 C  C   . ILE   B 2 442 ? 154.441 162.936 162.575 1.00 50.93  ? 339  ILE   R C   1 
ATOM   4127 O  O   . ILE   B 2 442 ? 154.016 162.973 161.414 1.00 50.93  ? 339  ILE   R O   1 
ATOM   4128 C  CB  . ILE   B 2 442 ? 153.294 164.345 164.338 1.00 50.93  ? 339  ILE   R CB  1 
ATOM   4129 C  CG1 . ILE   B 2 442 ? 152.355 164.318 165.538 1.00 50.93  ? 339  ILE   R CG1 1 
ATOM   4130 C  CG2 . ILE   B 2 442 ? 152.762 165.299 163.283 1.00 50.93  ? 339  ILE   R CG2 1 
ATOM   4131 C  CD1 . ILE   B 2 442 ? 150.930 164.126 165.184 1.00 50.93  ? 339  ILE   R CD1 1 
ATOM   4132 N  N   . GLU   B 2 443 ? 155.748 162.900 162.848 1.00 53.22  ? 340  GLU   R N   1 
ATOM   4133 C  CA  . GLU   B 2 443 ? 156.734 162.874 161.770 1.00 53.22  ? 340  GLU   R CA  1 
ATOM   4134 C  C   . GLU   B 2 443 ? 156.634 161.594 160.948 1.00 53.22  ? 340  GLU   R C   1 
ATOM   4135 O  O   . GLU   B 2 443 ? 156.752 161.628 159.716 1.00 53.22  ? 340  GLU   R O   1 
ATOM   4136 C  CB  . GLU   B 2 443 ? 158.139 163.039 162.344 1.00 53.22  ? 340  GLU   R CB  1 
ATOM   4137 C  CG  . GLU   B 2 443 ? 158.455 164.456 162.783 1.00 53.22  ? 340  GLU   R CG  1 
ATOM   4138 C  CD  . GLU   B 2 443 ? 158.066 165.491 161.743 1.00 53.22  ? 340  GLU   R CD  1 
ATOM   4139 O  OE1 . GLU   B 2 443 ? 158.824 165.664 160.766 1.00 53.22  ? 340  GLU   R OE1 1 
ATOM   4140 O  OE2 . GLU   B 2 443 ? 157.008 166.138 161.904 1.00 53.22  ? 340  GLU   R OE2 1 
ATOM   4141 N  N   . LEU   B 2 444 ? 156.412 160.457 161.613 1.00 49.25  ? 341  LEU   R N   1 
ATOM   4142 C  CA  . LEU   B 2 444 ? 156.206 159.206 160.888 1.00 49.25  ? 341  LEU   R CA  1 
ATOM   4143 C  C   . LEU   B 2 444 ? 154.944 159.260 160.035 1.00 49.25  ? 341  LEU   R C   1 
ATOM   4144 O  O   . LEU   B 2 444 ? 154.943 158.790 158.894 1.00 49.25  ? 341  LEU   R O   1 
ATOM   4145 C  CB  . LEU   B 2 444 ? 156.146 158.030 161.861 1.00 49.25  ? 341  LEU   R CB  1 
ATOM   4146 C  CG  . LEU   B 2 444 ? 156.200 156.637 161.226 1.00 49.25  ? 341  LEU   R CG  1 
ATOM   4147 C  CD1 . LEU   B 2 444 ? 157.281 156.560 160.166 1.00 49.25  ? 341  LEU   R CD1 1 
ATOM   4148 C  CD2 . LEU   B 2 444 ? 156.421 155.572 162.277 1.00 49.25  ? 341  LEU   R CD2 1 
ATOM   4149 N  N   . ALA   B 2 445 ? 153.864 159.840 160.565 1.00 48.77  ? 342  ALA   R N   1 
ATOM   4150 C  CA  . ALA   B 2 445 ? 152.642 159.977 159.777 1.00 48.77  ? 342  ALA   R CA  1 
ATOM   4151 C  C   . ALA   B 2 445 ? 152.856 160.878 158.564 1.00 48.77  ? 342  ALA   R C   1 
ATOM   4152 O  O   . ALA   B 2 445 ? 152.309 160.619 157.484 1.00 48.77  ? 342  ALA   R O   1 
ATOM   4153 C  CB  . ALA   B 2 445 ? 151.514 160.514 160.653 1.00 48.77  ? 342  ALA   R CB  1 
ATOM   4154 N  N   . LYS   B 2 446 ? 153.656 161.938 158.722 1.00 49.93  ? 343  LYS   R N   1 
ATOM   4155 C  CA  . LYS   B 2 446 ? 154.006 162.792 157.589 1.00 49.93  ? 343  LYS   R CA  1 
ATOM   4156 C  C   . LYS   B 2 446 ? 154.799 162.021 156.539 1.00 49.93  ? 343  LYS   R C   1 
ATOM   4157 O  O   . LYS   B 2 446 ? 154.559 162.171 155.333 1.00 49.93  ? 343  LYS   R O   1 
ATOM   4158 C  CB  . LYS   B 2 446 ? 154.809 163.999 158.070 1.00 49.93  ? 343  LYS   R CB  1 
ATOM   4159 C  CG  . LYS   B 2 446 ? 154.023 165.000 158.889 1.00 49.93  ? 343  LYS   R CG  1 
ATOM   4160 C  CD  . LYS   B 2 446 ? 154.796 166.295 159.045 1.00 49.93  ? 343  LYS   R CD  1 
ATOM   4161 C  CE  . LYS   B 2 446 ? 153.941 167.376 159.672 1.00 49.93  ? 343  LYS   R CE  1 
ATOM   4162 N  NZ  . LYS   B 2 446 ? 154.205 167.488 161.129 1.00 49.93  ? 343  LYS   R NZ  1 
ATOM   4163 N  N   . THR   B 2 447 ? 155.746 161.191 156.987 1.00 51.26  ? 344  THR   R N   1 
ATOM   4164 C  CA  . THR   B 2 447 ? 156.506 160.339 156.074 1.00 51.26  ? 344  THR   R CA  1 
ATOM   4165 C  C   . THR   B 2 447 ? 155.586 159.394 155.312 1.00 51.26  ? 344  THR   R C   1 
ATOM   4166 O  O   . THR   B 2 447 ? 155.767 159.165 154.109 1.00 51.26  ? 344  THR   R O   1 
ATOM   4167 C  CB  . THR   B 2 447 ? 157.549 159.542 156.861 1.00 51.26  ? 344  THR   R CB  1 
ATOM   4168 O  OG1 . THR   B 2 447 ? 158.441 160.442 157.528 1.00 51.26  ? 344  THR   R OG1 1 
ATOM   4169 C  CG2 . THR   B 2 447 ? 158.347 158.632 155.950 1.00 51.26  ? 344  THR   R CG2 1 
ATOM   4170 N  N   . LEU   B 2 448 ? 154.577 158.859 155.994 1.00 49.86  ? 345  LEU   R N   1 
ATOM   4171 C  CA  . LEU   B 2 448 ? 153.674 157.906 155.358 1.00 49.86  ? 345  LEU   R CA  1 
ATOM   4172 C  C   . LEU   B 2 448 ? 152.778 158.600 154.345 1.00 49.86  ? 345  LEU   R C   1 
ATOM   4173 O  O   . LEU   B 2 448 ? 152.460 158.031 153.296 1.00 49.86  ? 345  LEU   R O   1 
ATOM   4174 C  CB  . LEU   B 2 448 ? 152.835 157.190 156.414 1.00 49.86  ? 345  LEU   R CB  1 
ATOM   4175 C  CG  . LEU   B 2 448 ? 153.365 155.860 156.946 1.00 49.86  ? 345  LEU   R CG  1 
ATOM   4176 C  CD1 . LEU   B 2 448 ? 154.783 156.006 157.418 1.00 49.86  ? 345  LEU   R CD1 1 
ATOM   4177 C  CD2 . LEU   B 2 448 ? 152.519 155.392 158.087 1.00 49.86  ? 345  LEU   R CD2 1 
ATOM   4178 N  N   . VAL   B 2 449 ? 152.370 159.834 154.644 1.00 50.64  ? 346  VAL   R N   1 
ATOM   4179 C  CA  . VAL   B 2 449 ? 151.622 160.631 153.676 1.00 50.64  ? 346  VAL   R CA  1 
ATOM   4180 C  C   . VAL   B 2 449 ? 152.482 160.919 152.450 1.00 50.64  ? 346  VAL   R C   1 
ATOM   4181 O  O   . VAL   B 2 449 ? 152.002 160.875 151.309 1.00 50.64  ? 346  VAL   R O   1 
ATOM   4182 C  CB  . VAL   B 2 449 ? 151.109 161.922 154.343 1.00 50.64  ? 346  VAL   R CB  1 
ATOM   4183 C  CG1 . VAL   B 2 449 ? 150.605 162.916 153.314 1.00 50.64  ? 346  VAL   R CG1 1 
ATOM   4184 C  CG2 . VAL   B 2 449 ? 150.005 161.591 155.324 1.00 50.64  ? 346  VAL   R CG2 1 
ATOM   4185 N  N   . LEU   B 2 450 ? 153.773 161.188 152.666 1.00 52.81  ? 347  LEU   R N   1 
ATOM   4186 C  CA  . LEU   B 2 450 ? 154.688 161.409 151.548 1.00 52.81  ? 347  LEU   R CA  1 
ATOM   4187 C  C   . LEU   B 2 450 ? 154.829 160.161 150.680 1.00 52.81  ? 347  LEU   R C   1 
ATOM   4188 O  O   . LEU   B 2 450 ? 154.805 160.249 149.445 1.00 52.81  ? 347  LEU   R O   1 
ATOM   4189 C  CB  . LEU   B 2 450 ? 156.049 161.854 152.079 1.00 52.81  ? 347  LEU   R CB  1 
ATOM   4190 C  CG  . LEU   B 2 450 ? 157.210 161.919 151.091 1.00 52.81  ? 347  LEU   R CG  1 
ATOM   4191 C  CD1 . LEU   B 2 450 ? 156.956 162.980 150.039 1.00 52.81  ? 347  LEU   R CD1 1 
ATOM   4192 C  CD2 . LEU   B 2 450 ? 158.502 162.194 151.833 1.00 52.81  ? 347  LEU   R CD2 1 
ATOM   4193 N  N   . ILE   B 2 451 ? 154.959 158.991 151.310 1.00 52.30  ? 348  ILE   R N   1 
ATOM   4194 C  CA  . ILE   B 2 451 ? 155.051 157.732 150.566 1.00 52.30  ? 348  ILE   R CA  1 
ATOM   4195 C  C   . ILE   B 2 451 ? 153.770 157.481 149.778 1.00 52.30  ? 348  ILE   R C   1 
ATOM   4196 O  O   . ILE   B 2 451 ? 153.809 157.075 148.607 1.00 52.30  ? 348  ILE   R O   1 
ATOM   4197 C  CB  . ILE   B 2 451 ? 155.362 156.569 151.525 1.00 52.30  ? 348  ILE   R CB  1 
ATOM   4198 C  CG1 . ILE   B 2 451 ? 156.768 156.707 152.099 1.00 52.30  ? 348  ILE   R CG1 1 
ATOM   4199 C  CG2 . ILE   B 2 451 ? 155.224 155.233 150.829 1.00 52.30  ? 348  ILE   R CG2 1 
ATOM   4200 C  CD1 . ILE   B 2 451 ? 156.979 155.904 153.352 1.00 52.30  ? 348  ILE   R CD1 1 
ATOM   4201 N  N   . LEU   B 2 452 ? 152.618 157.744 150.403 1.00 52.04  ? 349  LEU   R N   1 
ATOM   4202 C  CA  . LEU   B 2 452 ? 151.334 157.556 149.738 1.00 52.04  ? 349  LEU   R CA  1 
ATOM   4203 C  C   . LEU   B 2 452 ? 151.186 158.471 148.529 1.00 52.04  ? 349  LEU   R C   1 
ATOM   4204 O  O   . LEU   B 2 452 ? 150.713 158.036 147.474 1.00 52.04  ? 349  LEU   R O   1 
ATOM   4205 C  CB  . LEU   B 2 452 ? 150.196 157.793 150.730 1.00 52.04  ? 349  LEU   R CB  1 
ATOM   4206 C  CG  . LEU   B 2 452 ? 148.811 158.094 150.156 1.00 52.04  ? 349  LEU   R CG  1 
ATOM   4207 C  CD1 . LEU   B 2 452 ? 148.140 156.829 149.661 1.00 52.04  ? 349  LEU   R CD1 1 
ATOM   4208 C  CD2 . LEU   B 2 452 ? 147.946 158.791 151.186 1.00 52.04  ? 349  LEU   R CD2 1 
ATOM   4209 N  N   . VAL   B 2 453 ? 151.597 159.736 148.649 1.00 55.24  ? 350  VAL   R N   1 
ATOM   4210 C  CA  . VAL   B 2 453 ? 151.403 160.634 147.513 1.00 55.24  ? 350  VAL   R CA  1 
ATOM   4211 C  C   . VAL   B 2 453 ? 152.420 160.364 146.403 1.00 55.24  ? 350  VAL   R C   1 
ATOM   4212 O  O   . VAL   B 2 453 ? 152.105 160.557 145.223 1.00 55.24  ? 350  VAL   R O   1 
ATOM   4213 C  CB  . VAL   B 2 453 ? 151.406 162.113 147.944 1.00 55.24  ? 350  VAL   R CB  1 
ATOM   4214 C  CG1 . VAL   B 2 453 ? 150.271 162.381 148.918 1.00 55.24  ? 350  VAL   R CG1 1 
ATOM   4215 C  CG2 . VAL   B 2 453 ? 152.736 162.529 148.532 1.00 55.24  ? 350  VAL   R CG2 1 
ATOM   4216 N  N   . VAL   B 2 454 ? 153.626 159.887 146.736 1.00 56.63  ? 351  VAL   R N   1 
ATOM   4217 C  CA  . VAL   B 2 454 ? 154.550 159.446 145.689 1.00 56.63  ? 351  VAL   R CA  1 
ATOM   4218 C  C   . VAL   B 2 454 ? 153.981 158.242 144.945 1.00 56.63  ? 351  VAL   R C   1 
ATOM   4219 O  O   . VAL   B 2 454 ? 154.041 158.172 143.709 1.00 56.63  ? 351  VAL   R O   1 
ATOM   4220 C  CB  . VAL   B 2 454 ? 155.941 159.151 146.280 1.00 56.63  ? 351  VAL   R CB  1 
ATOM   4221 C  CG1 . VAL   B 2 454 ? 156.848 158.553 145.231 1.00 56.63  ? 351  VAL   R CG1 1 
ATOM   4222 C  CG2 . VAL   B 2 454 ? 156.572 160.431 146.779 1.00 56.63  ? 351  VAL   R CG2 1 
ATOM   4223 N  N   . LEU   B 2 455 ? 153.398 157.290 145.683 1.00 58.57  ? 352  LEU   R N   1 
ATOM   4224 C  CA  . LEU   B 2 455 ? 152.758 156.138 145.053 1.00 58.57  ? 352  LEU   R CA  1 
ATOM   4225 C  C   . LEU   B 2 455 ? 151.586 156.562 144.176 1.00 58.57  ? 352  LEU   R C   1 
ATOM   4226 O  O   . LEU   B 2 455 ? 151.380 156.008 143.088 1.00 58.57  ? 352  LEU   R O   1 
ATOM   4227 C  CB  . LEU   B 2 455 ? 152.297 155.158 146.132 1.00 58.57  ? 352  LEU   R CB  1 
ATOM   4228 C  CG  . LEU   B 2 455 ? 151.743 153.791 145.738 1.00 58.57  ? 352  LEU   R CG  1 
ATOM   4229 C  CD1 . LEU   B 2 455 ? 152.289 152.743 146.679 1.00 58.57  ? 352  LEU   R CD1 1 
ATOM   4230 C  CD2 . LEU   B 2 455 ? 150.228 153.790 145.789 1.00 58.57  ? 352  LEU   R CD2 1 
ATOM   4231 N  N   . ILE   B 2 456 ? 150.810 157.546 144.640 1.00 59.68  ? 353  ILE   R N   1 
ATOM   4232 C  CA  . ILE   B 2 456 ? 149.679 158.059 143.870 1.00 59.68  ? 353  ILE   R CA  1 
ATOM   4233 C  C   . ILE   B 2 456 ? 150.165 158.691 142.571 1.00 59.68  ? 353  ILE   R C   1 
ATOM   4234 O  O   . ILE   B 2 456 ? 149.621 158.425 141.494 1.00 59.68  ? 353  ILE   R O   1 
ATOM   4235 C  CB  . ILE   B 2 456 ? 148.867 159.056 144.720 1.00 59.68  ? 353  ILE   R CB  1 
ATOM   4236 C  CG1 . ILE   B 2 456 ? 147.954 158.313 145.696 1.00 59.68  ? 353  ILE   R CG1 1 
ATOM   4237 C  CG2 . ILE   B 2 456 ? 148.045 159.993 143.845 1.00 59.68  ? 353  ILE   R CG2 1 
ATOM   4238 C  CD1 . ILE   B 2 456 ? 146.803 157.598 145.033 1.00 59.68  ? 353  ILE   R CD1 1 
ATOM   4239 N  N   . ILE   B 2 457 ? 151.220 159.508 142.655 1.00 63.91  ? 354  ILE   R N   1 
ATOM   4240 C  CA  . ILE   B 2 457 ? 151.772 160.167 141.472 1.00 63.91  ? 354  ILE   R CA  1 
ATOM   4241 C  C   . ILE   B 2 457 ? 152.301 159.138 140.479 1.00 63.91  ? 354  ILE   R C   1 
ATOM   4242 O  O   . ILE   B 2 457 ? 152.086 159.256 139.265 1.00 63.91  ? 354  ILE   R O   1 
ATOM   4243 C  CB  . ILE   B 2 457 ? 152.858 161.178 141.894 1.00 63.91  ? 354  ILE   R CB  1 
ATOM   4244 C  CG1 . ILE   B 2 457 ? 152.219 162.503 142.311 1.00 63.91  ? 354  ILE   R CG1 1 
ATOM   4245 C  CG2 . ILE   B 2 457 ? 153.879 161.415 140.788 1.00 63.91  ? 354  ILE   R CG2 1 
ATOM   4246 C  CD1 . ILE   B 2 457 ? 153.205 163.500 142.880 1.00 63.91  ? 354  ILE   R CD1 1 
ATOM   4247 N  N   . CYS   B 2 458 ? 152.964 158.094 140.980 1.00 68.92  ? 355  CYS   R N   1 
ATOM   4248 C  CA  . CYS   B 2 458 ? 153.561 157.106 140.087 1.00 68.92  ? 355  CYS   R CA  1 
ATOM   4249 C  C   . CYS   B 2 458 ? 152.509 156.231 139.409 1.00 68.92  ? 355  CYS   R C   1 
ATOM   4250 O  O   . CYS   B 2 458 ? 152.608 155.961 138.208 1.00 68.92  ? 355  CYS   R O   1 
ATOM   4251 C  CB  . CYS   B 2 458 ? 154.564 156.252 140.858 1.00 68.92  ? 355  CYS   R CB  1 
ATOM   4252 S  SG  . CYS   B 2 458 ? 156.069 157.146 141.317 1.00 68.92  ? 355  CYS   R SG  1 
ATOM   4253 N  N   . TRP   B 2 459 ? 151.496 155.777 140.147 1.00 68.70  ? 356  TRP   R N   1 
ATOM   4254 C  CA  . TRP   B 2 459 ? 150.525 154.840 139.594 1.00 68.70  ? 356  TRP   R CA  1 
ATOM   4255 C  C   . TRP   B 2 459 ? 149.235 155.503 139.120 1.00 68.70  ? 356  TRP   R C   1 
ATOM   4256 O  O   . TRP   B 2 459 ? 148.305 154.795 138.727 1.00 68.70  ? 356  TRP   R O   1 
ATOM   4257 C  CB  . TRP   B 2 459 ? 150.186 153.759 140.619 1.00 68.70  ? 356  TRP   R CB  1 
ATOM   4258 C  CG  . TRP   B 2 459 ? 151.249 152.724 140.831 1.00 68.70  ? 356  TRP   R CG  1 
ATOM   4259 C  CD1 . TRP   B 2 459 ? 152.396 152.865 141.552 1.00 68.70  ? 356  TRP   R CD1 1 
ATOM   4260 C  CD2 . TRP   B 2 459 ? 151.243 151.373 140.352 1.00 68.70  ? 356  TRP   R CD2 1 
ATOM   4261 N  NE1 . TRP   B 2 459 ? 153.111 151.694 141.542 1.00 68.70  ? 356  TRP   R NE1 1 
ATOM   4262 C  CE2 . TRP   B 2 459 ? 152.424 150.762 140.812 1.00 68.70  ? 356  TRP   R CE2 1 
ATOM   4263 C  CE3 . TRP   B 2 459 ? 150.357 150.624 139.573 1.00 68.70  ? 356  TRP   R CE3 1 
ATOM   4264 C  CZ2 . TRP   B 2 459 ? 152.740 149.437 140.524 1.00 68.70  ? 356  TRP   R CZ2 1 
ATOM   4265 C  CZ3 . TRP   B 2 459 ? 150.675 149.311 139.284 1.00 68.70  ? 356  TRP   R CZ3 1 
ATOM   4266 C  CH2 . TRP   B 2 459 ? 151.857 148.732 139.754 1.00 68.70  ? 356  TRP   R CH2 1 
ATOM   4267 N  N   . GLY   B 2 460 ? 149.147 156.831 139.150 1.00 79.36  ? 357  GLY   R N   1 
ATOM   4268 C  CA  . GLY   B 2 460 ? 147.954 157.523 138.714 1.00 79.36  ? 357  GLY   R CA  1 
ATOM   4269 C  C   . GLY   B 2 460 ? 147.588 157.357 137.251 1.00 79.36  ? 357  GLY   R C   1 
ATOM   4270 O  O   . GLY   B 2 460 ? 146.533 156.798 136.920 1.00 79.36  ? 357  GLY   R O   1 
ATOM   4271 N  N   . PRO   B 2 461 ? 148.435 157.872 136.348 1.00 84.46  ? 358  PRO   R N   1 
ATOM   4272 C  CA  . PRO   B 2 461 ? 148.121 157.777 134.913 1.00 84.46  ? 358  PRO   R CA  1 
ATOM   4273 C  C   . PRO   B 2 461 ? 147.975 156.359 134.403 1.00 84.46  ? 358  PRO   R C   1 
ATOM   4274 O  O   . PRO   B 2 461 ? 147.177 156.133 133.492 1.00 84.46  ? 358  PRO   R O   1 
ATOM   4275 C  CB  . PRO   B 2 461 ? 149.307 158.489 134.246 1.00 84.46  ? 358  PRO   R CB  1 
ATOM   4276 C  CG  . PRO   B 2 461 ? 150.371 158.550 135.291 1.00 84.46  ? 358  PRO   R CG  1 
ATOM   4277 C  CD  . PRO   B 2 461 ? 149.633 158.696 136.575 1.00 84.46  ? 358  PRO   R CD  1 
ATOM   4278 N  N   . LEU   B 2 462 ? 148.700 155.398 134.975 1.00 84.88  ? 359  LEU   R N   1 
ATOM   4279 C  CA  . LEU   B 2 462 ? 148.610 154.014 134.519 1.00 84.88  ? 359  LEU   R CA  1 
ATOM   4280 C  C   . LEU   B 2 462 ? 147.214 153.447 134.764 1.00 84.88  ? 359  LEU   R C   1 
ATOM   4281 O  O   . LEU   B 2 462 ? 146.549 152.941 133.843 1.00 84.88  ? 359  LEU   R O   1 
ATOM   4282 C  CB  . LEU   B 2 462 ? 149.661 153.184 135.249 1.00 84.88  ? 359  LEU   R CB  1 
ATOM   4283 C  CG  . LEU   B 2 462 ? 149.819 151.734 134.826 1.00 84.88  ? 359  LEU   R CG  1 
ATOM   4284 C  CD1 . LEU   B 2 462 ? 150.319 151.692 133.408 1.00 84.88  ? 359  LEU   R CD1 1 
ATOM   4285 C  CD2 . LEU   B 2 462 ? 150.738 150.993 135.749 1.00 84.88  ? 359  LEU   R CD2 1 
ATOM   4286 N  N   . LEU   B 2 463 ? 146.737 153.568 136.004 1.00 83.95  ? 360  LEU   R N   1 
ATOM   4287 C  CA  . LEU   B 2 463 ? 145.385 153.138 136.325 1.00 83.95  ? 360  LEU   R CA  1 
ATOM   4288 C  C   . LEU   B 2 463 ? 144.351 153.979 135.593 1.00 83.95  ? 360  LEU   R C   1 
ATOM   4289 O  O   . LEU   B 2 463 ? 143.261 153.487 135.302 1.00 83.95  ? 360  LEU   R O   1 
ATOM   4290 C  CB  . LEU   B 2 463 ? 145.152 153.185 137.837 1.00 83.95  ? 360  LEU   R CB  1 
ATOM   4291 C  CG  . LEU   B 2 463 ? 145.605 152.006 138.716 1.00 83.95  ? 360  LEU   R CG  1 
ATOM   4292 C  CD1 . LEU   B 2 463 ? 144.932 150.716 138.306 1.00 83.95  ? 360  LEU   R CD1 1 
ATOM   4293 C  CD2 . LEU   B 2 463 ? 147.106 151.805 138.738 1.00 83.95  ? 360  LEU   R CD2 1 
ATOM   4294 N  N   . ALA   B 2 464 ? 144.685 155.227 135.249 1.00 89.52  ? 361  ALA   R N   1 
ATOM   4295 C  CA  . ALA   B 2 464 ? 143.797 156.016 134.398 1.00 89.52  ? 361  ALA   R CA  1 
ATOM   4296 C  C   . ALA   B 2 464 ? 143.689 155.420 132.996 1.00 89.52  ? 361  ALA   R C   1 
ATOM   4297 O  O   . ALA   B 2 464 ? 142.618 155.465 132.379 1.00 89.52  ? 361  ALA   R O   1 
ATOM   4298 C  CB  . ALA   B 2 464 ? 144.278 157.464 134.331 1.00 89.52  ? 361  ALA   R CB  1 
ATOM   4299 N  N   . ILE   B 2 465 ? 144.790 154.877 132.468 1.00 90.00  ? 362  ILE   R N   1 
ATOM   4300 C  CA  . ILE   B 2 465 ? 144.725 154.196 131.174 1.00 90.00  ? 362  ILE   R CA  1 
ATOM   4301 C  C   . ILE   B 2 465 ? 143.856 152.949 131.269 1.00 90.00  ? 362  ILE   R C   1 
ATOM   4302 O  O   . ILE   B 2 465 ? 143.085 152.653 130.349 1.00 90.00  ? 362  ILE   R O   1 
ATOM   4303 C  CB  . ILE   B 2 465 ? 146.127 153.864 130.619 1.00 90.00  ? 362  ILE   R CB  1 
ATOM   4304 C  CG1 . ILE   B 2 465 ? 147.045 155.086 130.572 1.00 90.00  ? 362  ILE   R CG1 1 
ATOM   4305 C  CG2 . ILE   B 2 465 ? 146.023 153.292 129.216 1.00 90.00  ? 362  ILE   R CG2 1 
ATOM   4306 C  CD1 . ILE   B 2 465 ? 146.414 156.344 129.996 1.00 90.00  ? 362  ILE   R CD1 1 
ATOM   4307 N  N   . MET   B 2 466 ? 143.953 152.199 132.375 1.00 89.96  ? 363  MET   R N   1 
ATOM   4308 C  CA  . MET   B 2 466 ? 143.003 151.086 132.517 1.00 89.96  ? 363  MET   R CA  1 
ATOM   4309 C  C   . MET   B 2 466 ? 141.559 151.571 132.656 1.00 89.96  ? 363  MET   R C   1 
ATOM   4310 O  O   . MET   B 2 466 ? 140.637 150.902 132.170 1.00 89.96  ? 363  MET   R O   1 
ATOM   4311 C  CB  . MET   B 2 466 ? 143.334 150.131 133.669 1.00 89.96  ? 363  MET   R CB  1 
ATOM   4312 C  CG  . MET   B 2 466 ? 144.428 149.096 133.397 1.00 89.96  ? 363  MET   R CG  1 
ATOM   4313 S  SD  . MET   B 2 466 ? 145.469 148.636 134.798 1.00 89.96  ? 363  MET   R SD  1 
ATOM   4314 C  CE  . MET   B 2 466 ? 146.671 149.933 134.839 1.00 89.96  ? 363  MET   R CE  1 
ATOM   4315 N  N   . VAL   B 2 467 ? 141.338 152.718 133.310 1.00 93.22  ? 364  VAL   R N   1 
ATOM   4316 C  CA  . VAL   B 2 467 ? 139.991 153.296 133.377 1.00 93.22  ? 364  VAL   R CA  1 
ATOM   4317 C  C   . VAL   B 2 467 ? 139.462 153.588 131.980 1.00 93.22  ? 364  VAL   R C   1 
ATOM   4318 O  O   . VAL   B 2 467 ? 138.336 153.210 131.631 1.00 93.22  ? 364  VAL   R O   1 
ATOM   4319 C  CB  . VAL   B 2 467 ? 139.974 154.568 134.248 1.00 93.22  ? 364  VAL   R CB  1 
ATOM   4320 C  CG1 . VAL   B 2 467 ? 138.623 155.250 134.154 1.00 93.22  ? 364  VAL   R CG1 1 
ATOM   4321 C  CG2 . VAL   B 2 467 ? 140.202 154.230 135.696 1.00 93.22  ? 364  VAL   R CG2 1 
ATOM   4322 N  N   . TYR   B 2 468 ? 140.275 154.243 131.152 1.00 96.19  ? 365  TYR   R N   1 
ATOM   4323 C  CA  . TYR   B 2 468 ? 139.819 154.588 129.812 1.00 96.19  ? 365  TYR   R CA  1 
ATOM   4324 C  C   . TYR   B 2 468 ? 139.704 153.354 128.922 1.00 96.19  ? 365  TYR   R C   1 
ATOM   4325 O  O   . TYR   B 2 468 ? 138.922 153.361 127.967 1.00 96.19  ? 365  TYR   R O   1 
ATOM   4326 C  CB  . TYR   B 2 468 ? 140.752 155.627 129.188 1.00 96.19  ? 365  TYR   R CB  1 
ATOM   4327 C  CG  . TYR   B 2 468 ? 140.319 156.081 127.817 1.00 96.19  ? 365  TYR   R CG  1 
ATOM   4328 C  CD1 . TYR   B 2 468 ? 139.258 156.965 127.667 1.00 96.19  ? 365  TYR   R CD1 1 
ATOM   4329 C  CD2 . TYR   B 2 468 ? 140.960 155.630 126.675 1.00 96.19  ? 365  TYR   R CD2 1 
ATOM   4330 C  CE1 . TYR   B 2 468 ? 138.848 157.388 126.419 1.00 96.19  ? 365  TYR   R CE1 1 
ATOM   4331 C  CE2 . TYR   B 2 468 ? 140.555 156.049 125.422 1.00 96.19  ? 365  TYR   R CE2 1 
ATOM   4332 C  CZ  . TYR   B 2 468 ? 139.500 156.926 125.300 1.00 96.19  ? 365  TYR   R CZ  1 
ATOM   4333 O  OH  . TYR   B 2 468 ? 139.097 157.344 124.052 1.00 96.19  ? 365  TYR   R OH  1 
ATOM   4334 N  N   . ASP   B 2 469 ? 140.462 152.298 129.225 1.00 95.10  ? 366  ASP   R N   1 
ATOM   4335 C  CA  . ASP   B 2 469 ? 140.241 151.003 128.591 1.00 95.10  ? 366  ASP   R CA  1 
ATOM   4336 C  C   . ASP   B 2 469 ? 138.873 150.440 128.946 1.00 95.10  ? 366  ASP   R C   1 
ATOM   4337 O  O   . ASP   B 2 469 ? 138.200 149.852 128.091 1.00 95.10  ? 366  ASP   R O   1 
ATOM   4338 C  CB  . ASP   B 2 469 ? 141.340 150.027 129.011 1.00 95.10  ? 366  ASP   R CB  1 
ATOM   4339 C  CG  . ASP   B 2 469 ? 141.330 148.743 128.199 1.00 95.10  ? 366  ASP   R CG  1 
ATOM   4340 O  OD1 . ASP   B 2 469 ? 140.642 148.682 127.160 1.00 95.10  ? 366  ASP   R OD1 1 
ATOM   4341 O  OD2 . ASP   B 2 469 ? 142.011 147.781 128.610 1.00 95.10  ? 366  ASP   R OD2 1 
ATOM   4342 N  N   . VAL   B 2 470 ? 138.458 150.588 130.206 1.00 97.12  ? 367  VAL   R N   1 
ATOM   4343 C  CA  . VAL   B 2 470 ? 137.156 150.072 130.624 1.00 97.12  ? 367  VAL   R CA  1 
ATOM   4344 C  C   . VAL   B 2 470 ? 136.029 150.810 129.907 1.00 97.12  ? 367  VAL   R C   1 
ATOM   4345 O  O   . VAL   B 2 470 ? 135.085 150.194 129.399 1.00 97.12  ? 367  VAL   R O   1 
ATOM   4346 C  CB  . VAL   B 2 470 ? 137.012 150.147 132.155 1.00 97.12  ? 367  VAL   R CB  1 
ATOM   4347 C  CG1 . VAL   B 2 470 ? 135.593 149.811 132.581 1.00 97.12  ? 367  VAL   R CG1 1 
ATOM   4348 C  CG2 . VAL   B 2 470 ? 137.976 149.178 132.815 1.00 97.12  ? 367  VAL   R CG2 1 
ATOM   4349 N  N   . PHE   B 2 471 ? 136.127 152.133 129.822 1.00 102.29 ? 368  PHE   R N   1 
ATOM   4350 C  CA  . PHE   B 2 471 ? 135.102 152.956 129.177 1.00 102.29 ? 368  PHE   R CA  1 
ATOM   4351 C  C   . PHE   B 2 471 ? 135.631 153.427 127.825 1.00 102.29 ? 368  PHE   R C   1 
ATOM   4352 O  O   . PHE   B 2 471 ? 136.242 154.489 127.710 1.00 102.29 ? 368  PHE   R O   1 
ATOM   4353 C  CB  . PHE   B 2 471 ? 134.707 154.130 130.069 1.00 102.29 ? 368  PHE   R CB  1 
ATOM   4354 C  CG  . PHE   B 2 471 ? 133.682 153.786 131.120 1.00 102.29 ? 368  PHE   R CG  1 
ATOM   4355 C  CD1 . PHE   B 2 471 ? 132.952 154.790 131.738 1.00 102.29 ? 368  PHE   R CD1 1 
ATOM   4356 C  CD2 . PHE   B 2 471 ? 133.425 152.468 131.468 1.00 102.29 ? 368  PHE   R CD2 1 
ATOM   4357 C  CE1 . PHE   B 2 471 ? 132.003 154.487 132.697 1.00 102.29 ? 368  PHE   R CE1 1 
ATOM   4358 C  CE2 . PHE   B 2 471 ? 132.478 152.157 132.425 1.00 102.29 ? 368  PHE   R CE2 1 
ATOM   4359 C  CZ  . PHE   B 2 471 ? 131.765 153.168 133.040 1.00 102.29 ? 368  PHE   R CZ  1 
ATOM   4360 N  N   . GLY   B 2 472 ? 135.377 152.632 126.793 1.00 100.15 ? 369  GLY   R N   1 
ATOM   4361 C  CA  . GLY   B 2 472 ? 135.749 152.991 125.442 1.00 100.15 ? 369  GLY   R CA  1 
ATOM   4362 C  C   . GLY   B 2 472 ? 137.029 152.309 124.989 1.00 100.15 ? 369  GLY   R C   1 
ATOM   4363 O  O   . GLY   B 2 472 ? 137.827 151.811 125.786 1.00 100.15 ? 369  GLY   R O   1 
ATOM   4364 N  N   . LYS   B 2 473 ? 137.218 152.284 123.673 1.00 101.52 ? 370  LYS   R N   1 
ATOM   4365 C  CA  . LYS   B 2 473 ? 138.410 151.714 123.068 1.00 101.52 ? 370  LYS   R CA  1 
ATOM   4366 C  C   . LYS   B 2 473 ? 139.496 152.786 122.980 1.00 101.52 ? 370  LYS   R C   1 
ATOM   4367 O  O   . LYS   B 2 473 ? 139.338 153.902 123.479 1.00 101.52 ? 370  LYS   R O   1 
ATOM   4368 C  CB  . LYS   B 2 473 ? 138.077 151.126 121.698 1.00 101.52 ? 370  LYS   R CB  1 
ATOM   4369 N  N   . MET   B 2 474 ? 140.615 152.458 122.338 1.00 103.49 ? 371  MET   R N   1 
ATOM   4370 C  CA  . MET   B 2 474 ? 141.704 153.408 122.176 1.00 103.49 ? 371  MET   R CA  1 
ATOM   4371 C  C   . MET   B 2 474 ? 142.419 153.131 120.863 1.00 103.49 ? 371  MET   R C   1 
ATOM   4372 O  O   . MET   B 2 474 ? 142.177 152.122 120.197 1.00 103.49 ? 371  MET   R O   1 
ATOM   4373 C  CB  . MET   B 2 474 ? 142.704 153.337 123.333 1.00 103.49 ? 371  MET   R CB  1 
ATOM   4374 C  CG  . MET   B 2 474 ? 143.587 152.100 123.326 1.00 103.49 ? 371  MET   R CG  1 
ATOM   4375 S  SD  . MET   B 2 474 ? 142.677 150.593 123.683 1.00 103.49 ? 371  MET   R SD  1 
ATOM   4376 C  CE  . MET   B 2 474 ? 142.283 150.874 125.402 1.00 103.49 ? 371  MET   R CE  1 
ATOM   4377 N  N   . ASN   B 2 475 ? 143.308 154.046 120.500 1.00 99.55  ? 372  ASN   R N   1 
ATOM   4378 C  CA  . ASN   B 2 475 ? 144.183 153.872 119.357 1.00 99.55  ? 372  ASN   R CA  1 
ATOM   4379 C  C   . ASN   B 2 475 ? 145.558 153.420 119.841 1.00 99.55  ? 372  ASN   R C   1 
ATOM   4380 O  O   . ASN   B 2 475 ? 145.771 153.156 121.028 1.00 99.55  ? 372  ASN   R O   1 
ATOM   4381 C  CB  . ASN   B 2 475 ? 144.259 155.167 118.549 1.00 99.55  ? 372  ASN   R CB  1 
ATOM   4382 C  CG  . ASN   B 2 475 ? 144.476 156.382 119.421 1.00 99.55  ? 372  ASN   R CG  1 
ATOM   4383 O  OD1 . ASN   B 2 475 ? 144.431 156.292 120.645 1.00 99.55  ? 372  ASN   R OD1 1 
ATOM   4384 N  ND2 . ASN   B 2 475 ? 144.717 157.527 118.794 1.00 99.55  ? 372  ASN   R ND2 1 
ATOM   4385 N  N   . LYS   B 2 476 ? 146.510 153.332 118.914 1.00 102.41 ? 373  LYS   R N   1 
ATOM   4386 C  CA  . LYS   B 2 476 ? 147.852 152.883 119.256 1.00 102.41 ? 373  LYS   R CA  1 
ATOM   4387 C  C   . LYS   B 2 476 ? 148.644 153.925 120.033 1.00 102.41 ? 373  LYS   R C   1 
ATOM   4388 O  O   . LYS   B 2 476 ? 149.626 153.569 120.689 1.00 102.41 ? 373  LYS   R O   1 
ATOM   4389 C  CB  . LYS   B 2 476 ? 148.615 152.500 117.987 1.00 102.41 ? 373  LYS   R CB  1 
ATOM   4390 C  CG  . LYS   B 2 476 ? 149.640 151.397 118.182 1.00 102.41 ? 373  LYS   R CG  1 
ATOM   4391 C  CD  . LYS   B 2 476 ? 150.308 151.031 116.867 1.00 102.41 ? 373  LYS   R CD  1 
ATOM   4392 C  CE  . LYS   B 2 476 ? 150.961 152.244 116.225 1.00 102.41 ? 373  LYS   R CE  1 
ATOM   4393 N  NZ  . LYS   B 2 476 ? 152.033 152.813 117.086 1.00 102.41 ? 373  LYS   R NZ  1 
ATOM   4394 N  N   . LEU   B 2 477 ? 148.246 155.198 119.971 1.00 101.06 ? 374  LEU   R N   1 
ATOM   4395 C  CA  . LEU   B 2 477 ? 148.948 156.232 120.726 1.00 101.06 ? 374  LEU   R CA  1 
ATOM   4396 C  C   . LEU   B 2 477 ? 148.724 156.067 122.226 1.00 101.06 ? 374  LEU   R C   1 
ATOM   4397 O  O   . LEU   B 2 477 ? 149.640 156.287 123.029 1.00 101.06 ? 374  LEU   R O   1 
ATOM   4398 C  CB  . LEU   B 2 477 ? 148.492 157.616 120.261 1.00 101.06 ? 374  LEU   R CB  1 
ATOM   4399 C  CG  . LEU   B 2 477 ? 149.091 158.839 120.961 1.00 101.06 ? 374  LEU   R CG  1 
ATOM   4400 C  CD1 . LEU   B 2 477 ? 150.613 158.770 120.973 1.00 101.06 ? 374  LEU   R CD1 1 
ATOM   4401 C  CD2 . LEU   B 2 477 ? 148.617 160.126 120.309 1.00 101.06 ? 374  LEU   R CD2 1 
ATOM   4402 N  N   . ILE   B 2 478 ? 147.510 155.688 122.621 1.00 98.57  ? 375  ILE   R N   1 
ATOM   4403 C  CA  . ILE   B 2 478 ? 147.226 155.469 124.033 1.00 98.57  ? 375  ILE   R CA  1 
ATOM   4404 C  C   . ILE   B 2 478 ? 147.950 154.226 124.539 1.00 98.57  ? 375  ILE   R C   1 
ATOM   4405 O  O   . ILE   B 2 478 ? 148.446 154.202 125.670 1.00 98.57  ? 375  ILE   R O   1 
ATOM   4406 C  CB  . ILE   B 2 478 ? 145.705 155.418 124.256 1.00 98.57  ? 375  ILE   R CB  1 
ATOM   4407 C  CG1 . ILE   B 2 478 ? 145.114 156.779 123.879 1.00 98.57  ? 375  ILE   R CG1 1 
ATOM   4408 C  CG2 . ILE   B 2 478 ? 145.364 155.083 125.695 1.00 98.57  ? 375  ILE   R CG2 1 
ATOM   4409 C  CD1 . ILE   B 2 478 ? 143.617 156.823 123.797 1.00 98.57  ? 375  ILE   R CD1 1 
ATOM   4410 N  N   . LYS   B 2 479 ? 148.064 153.192 123.703 1.00 94.68  ? 376  LYS   R N   1 
ATOM   4411 C  CA  . LYS   B 2 479 ? 148.906 152.054 124.061 1.00 94.68  ? 376  LYS   R CA  1 
ATOM   4412 C  C   . LYS   B 2 479 ? 150.375 152.450 124.150 1.00 94.68  ? 376  LYS   R C   1 
ATOM   4413 O  O   . LYS   B 2 479 ? 151.113 151.920 124.992 1.00 94.68  ? 376  LYS   R O   1 
ATOM   4414 C  CB  . LYS   B 2 479 ? 148.725 150.926 123.049 1.00 94.68  ? 376  LYS   R CB  1 
ATOM   4415 C  CG  . LYS   B 2 479 ? 147.306 150.399 122.963 1.00 94.68  ? 376  LYS   R CG  1 
ATOM   4416 C  CD  . LYS   B 2 479 ? 147.129 149.491 121.758 1.00 94.68  ? 376  LYS   R CD  1 
ATOM   4417 C  CE  . LYS   B 2 479 ? 147.282 148.030 122.138 1.00 94.68  ? 376  LYS   R CE  1 
ATOM   4418 N  NZ  . LYS   B 2 479 ? 146.897 147.125 121.021 1.00 94.68  ? 376  LYS   R NZ  1 
ATOM   4419 N  N   . THR   B 2 480 ? 150.812 153.381 123.300 1.00 97.93  ? 377  THR   R N   1 
ATOM   4420 C  CA  . THR   B 2 480 ? 152.188 153.857 123.356 1.00 97.93  ? 377  THR   R CA  1 
ATOM   4421 C  C   . THR   B 2 480 ? 152.466 154.602 124.657 1.00 97.93  ? 377  THR   R C   1 
ATOM   4422 O  O   . THR   B 2 480 ? 153.497 154.374 125.300 1.00 97.93  ? 377  THR   R O   1 
ATOM   4423 C  CB  . THR   B 2 480 ? 152.476 154.750 122.150 1.00 97.93  ? 377  THR   R CB  1 
ATOM   4424 O  OG1 . THR   B 2 480 ? 152.282 153.998 120.946 1.00 97.93  ? 377  THR   R OG1 1 
ATOM   4425 C  CG2 . THR   B 2 480 ? 153.906 155.262 122.186 1.00 97.93  ? 377  THR   R CG2 1 
ATOM   4426 N  N   . VAL   B 2 481 ? 151.546 155.473 125.079 1.00 93.57  ? 378  VAL   R N   1 
ATOM   4427 C  CA  . VAL   B 2 481 ? 151.782 156.204 126.323 1.00 93.57  ? 378  VAL   R CA  1 
ATOM   4428 C  C   . VAL   B 2 481 ? 151.566 155.284 127.524 1.00 93.57  ? 378  VAL   R C   1 
ATOM   4429 O  O   . VAL   B 2 481 ? 152.162 155.493 128.585 1.00 93.57  ? 378  VAL   R O   1 
ATOM   4430 C  CB  . VAL   B 2 481 ? 150.918 157.484 126.390 1.00 93.57  ? 378  VAL   R CB  1 
ATOM   4431 C  CG1 . VAL   B 2 481 ? 149.441 157.168 126.453 1.00 93.57  ? 378  VAL   R CG1 1 
ATOM   4432 C  CG2 . VAL   B 2 481 ? 151.344 158.394 127.542 1.00 93.57  ? 378  VAL   R CG2 1 
ATOM   4433 N  N   . PHE   B 2 482 ? 150.761 154.228 127.361 1.00 90.70  ? 379  PHE   R N   1 
ATOM   4434 C  CA  . PHE   B 2 482 ? 150.690 153.159 128.354 1.00 90.70  ? 379  PHE   R CA  1 
ATOM   4435 C  C   . PHE   B 2 482 ? 152.053 152.515 128.562 1.00 90.70  ? 379  PHE   R C   1 
ATOM   4436 O  O   . PHE   B 2 482 ? 152.535 152.400 129.696 1.00 90.70  ? 379  PHE   R O   1 
ATOM   4437 C  CB  . PHE   B 2 482 ? 149.676 152.112 127.895 1.00 90.70  ? 379  PHE   R CB  1 
ATOM   4438 C  CG  . PHE   B 2 482 ? 149.487 150.971 128.851 1.00 90.70  ? 379  PHE   R CG  1 
ATOM   4439 C  CD1 . PHE   B 2 482 ? 148.751 151.124 130.009 1.00 90.70  ? 379  PHE   R CD1 1 
ATOM   4440 C  CD2 . PHE   B 2 482 ? 150.059 149.737 128.588 1.00 90.70  ? 379  PHE   R CD2 1 
ATOM   4441 C  CE1 . PHE   B 2 482 ? 148.570 150.060 130.876 1.00 90.70  ? 379  PHE   R CE1 1 
ATOM   4442 C  CE2 . PHE   B 2 482 ? 149.894 148.677 129.458 1.00 90.70  ? 379  PHE   R CE2 1 
ATOM   4443 C  CZ  . PHE   B 2 482 ? 149.151 148.841 130.604 1.00 90.70  ? 379  PHE   R CZ  1 
ATOM   4444 N  N   . ALA   B 2 483 ? 152.696 152.108 127.465 1.00 88.15  ? 380  ALA   R N   1 
ATOM   4445 C  CA  . ALA   B 2 483 ? 154.020 151.502 127.555 1.00 88.15  ? 380  ALA   R CA  1 
ATOM   4446 C  C   . ALA   B 2 483 ? 155.060 152.489 128.069 1.00 88.15  ? 380  ALA   R C   1 
ATOM   4447 O  O   . ALA   B 2 483 ? 156.013 152.089 128.746 1.00 88.15  ? 380  ALA   R O   1 
ATOM   4448 C  CB  . ALA   B 2 483 ? 154.439 150.956 126.192 1.00 88.15  ? 380  ALA   R CB  1 
ATOM   4449 N  N   . PHE   B 2 484 ? 154.898 153.775 127.754 1.00 92.89  ? 381  PHE   R N   1 
ATOM   4450 C  CA  . PHE   B 2 484 ? 155.869 154.773 128.188 1.00 92.89  ? 381  PHE   R CA  1 
ATOM   4451 C  C   . PHE   B 2 484 ? 155.756 155.057 129.682 1.00 92.89  ? 381  PHE   R C   1 
ATOM   4452 O  O   . PHE   B 2 484 ? 156.771 155.125 130.384 1.00 92.89  ? 381  PHE   R O   1 
ATOM   4453 C  CB  . PHE   B 2 484 ? 155.691 156.056 127.378 1.00 92.89  ? 381  PHE   R CB  1 
ATOM   4454 C  CG  . PHE   B 2 484 ? 156.677 157.134 127.724 1.00 92.89  ? 381  PHE   R CG  1 
ATOM   4455 C  CD1 . PHE   B 2 484 ? 157.989 157.056 127.283 1.00 92.89  ? 381  PHE   R CD1 1 
ATOM   4456 C  CD2 . PHE   B 2 484 ? 156.290 158.232 128.477 1.00 92.89  ? 381  PHE   R CD2 1 
ATOM   4457 C  CE1 . PHE   B 2 484 ? 158.902 158.047 127.595 1.00 92.89  ? 381  PHE   R CE1 1 
ATOM   4458 C  CE2 . PHE   B 2 484 ? 157.197 159.229 128.792 1.00 92.89  ? 381  PHE   R CE2 1 
ATOM   4459 C  CZ  . PHE   B 2 484 ? 158.505 159.136 128.350 1.00 92.89  ? 381  PHE   R CZ  1 
ATOM   4460 N  N   . CYS   B 2 485 ? 154.534 155.228 130.187 1.00 90.86  ? 382  CYS   R N   1 
ATOM   4461 C  CA  . CYS   B 2 485 ? 154.315 155.550 131.591 1.00 90.86  ? 382  CYS   R CA  1 
ATOM   4462 C  C   . CYS   B 2 485 ? 154.261 154.319 132.480 1.00 90.86  ? 382  CYS   R C   1 
ATOM   4463 O  O   . CYS   B 2 485 ? 154.154 154.466 133.701 1.00 90.86  ? 382  CYS   R O   1 
ATOM   4464 C  CB  . CYS   B 2 485 ? 153.025 156.356 131.754 1.00 90.86  ? 382  CYS   R CB  1 
ATOM   4465 S  SG  . CYS   B 2 485 ? 151.529 155.350 131.825 1.00 90.86  ? 382  CYS   R SG  1 
ATOM   4466 N  N   . SER   B 2 486 ? 154.329 153.116 131.910 1.00 87.69  ? 383  SER   R N   1 
ATOM   4467 C  CA  . SER   B 2 486 ? 154.408 151.920 132.735 1.00 87.69  ? 383  SER   R CA  1 
ATOM   4468 C  C   . SER   B 2 486 ? 155.755 151.758 133.430 1.00 87.69  ? 383  SER   R C   1 
ATOM   4469 O  O   . SER   B 2 486 ? 155.882 150.884 134.292 1.00 87.69  ? 383  SER   R O   1 
ATOM   4470 C  CB  . SER   B 2 486 ? 154.104 150.696 131.877 1.00 87.69  ? 383  SER   R CB  1 
ATOM   4471 O  OG  . SER   B 2 486 ? 152.795 150.766 131.346 1.00 87.69  ? 383  SER   R OG  1 
ATOM   4472 N  N   . MET   B 2 487 ? 156.757 152.565 133.083 1.00 81.07  ? 384  MET   R N   1 
ATOM   4473 C  CA  . MET   B 2 487 ? 158.022 152.565 133.805 1.00 81.07  ? 384  MET   R CA  1 
ATOM   4474 C  C   . MET   B 2 487 ? 157.955 153.350 135.110 1.00 81.07  ? 384  MET   R C   1 
ATOM   4475 O  O   . MET   B 2 487 ? 158.894 153.279 135.915 1.00 81.07  ? 384  MET   R O   1 
ATOM   4476 C  CB  . MET   B 2 487 ? 159.128 153.132 132.915 1.00 81.07  ? 384  MET   R CB  1 
ATOM   4477 C  CG  . MET   B 2 487 ? 159.325 152.365 131.621 1.00 81.07  ? 384  MET   R CG  1 
ATOM   4478 S  SD  . MET   B 2 487 ? 159.381 150.581 131.853 1.00 81.07  ? 384  MET   R SD  1 
ATOM   4479 C  CE  . MET   B 2 487 ? 160.865 150.412 132.840 1.00 81.07  ? 384  MET   R CE  1 
ATOM   4480 N  N   . LEU   B 2 488 ? 156.864 154.086 135.340 1.00 75.59  ? 385  LEU   R N   1 
ATOM   4481 C  CA  . LEU   B 2 488 ? 156.682 154.794 136.599 1.00 75.59  ? 385  LEU   R CA  1 
ATOM   4482 C  C   . LEU   B 2 488 ? 156.564 153.843 137.781 1.00 75.59  ? 385  LEU   R C   1 
ATOM   4483 O  O   . LEU   B 2 488 ? 156.862 154.242 138.908 1.00 75.59  ? 385  LEU   R O   1 
ATOM   4484 C  CB  . LEU   B 2 488 ? 155.445 155.685 136.521 1.00 75.59  ? 385  LEU   R CB  1 
ATOM   4485 C  CG  . LEU   B 2 488 ? 155.565 156.944 135.661 1.00 75.59  ? 385  LEU   R CG  1 
ATOM   4486 C  CD1 . LEU   B 2 488 ? 154.292 157.765 135.741 1.00 75.59  ? 385  LEU   R CD1 1 
ATOM   4487 C  CD2 . LEU   B 2 488 ? 156.758 157.770 136.087 1.00 75.59  ? 385  LEU   R CD2 1 
ATOM   4488 N  N   . CYS   B 2 489 ? 156.160 152.594 137.545 1.00 73.08  ? 386  CYS   R N   1 
ATOM   4489 C  CA  . CYS   B 2 489 ? 156.132 151.593 138.606 1.00 73.08  ? 386  CYS   R CA  1 
ATOM   4490 C  C   . CYS   B 2 489 ? 157.539 151.286 139.099 1.00 73.08  ? 386  CYS   R C   1 
ATOM   4491 O  O   . CYS   B 2 489 ? 157.810 151.286 140.310 1.00 73.08  ? 386  CYS   R O   1 
ATOM   4492 C  CB  . CYS   B 2 489 ? 155.473 150.325 138.079 1.00 73.08  ? 386  CYS   R CB  1 
ATOM   4493 S  SG  . CYS   B 2 489 ? 153.819 150.604 137.468 1.00 73.08  ? 386  CYS   R SG  1 
ATOM   4494 N  N   . LEU   B 2 490 ? 158.452 151.029 138.162 1.00 71.42  ? 387  LEU   R N   1 
ATOM   4495 C  CA  . LEU   B 2 490 ? 159.846 150.805 138.513 1.00 71.42  ? 387  LEU   R CA  1 
ATOM   4496 C  C   . LEU   B 2 490 ? 160.472 152.063 139.098 1.00 71.42  ? 387  LEU   R C   1 
ATOM   4497 O  O   . LEU   B 2 490 ? 161.342 151.976 139.969 1.00 71.42  ? 387  LEU   R O   1 
ATOM   4498 C  CB  . LEU   B 2 490 ? 160.616 150.338 137.281 1.00 71.42  ? 387  LEU   R CB  1 
ATOM   4499 C  CG  . LEU   B 2 490 ? 162.022 149.797 137.514 1.00 71.42  ? 387  LEU   R CG  1 
ATOM   4500 C  CD1 . LEU   B 2 490 ? 161.940 148.423 138.156 1.00 71.42  ? 387  LEU   R CD1 1 
ATOM   4501 C  CD2 . LEU   B 2 490 ? 162.800 149.747 136.212 1.00 71.42  ? 387  LEU   R CD2 1 
ATOM   4502 N  N   . LEU   B 2 491 ? 160.023 153.238 138.652 1.00 70.29  ? 388  LEU   R N   1 
ATOM   4503 C  CA  . LEU   B 2 491 ? 160.514 154.480 139.242 1.00 70.29  ? 388  LEU   R CA  1 
ATOM   4504 C  C   . LEU   B 2 491 ? 160.043 154.633 140.689 1.00 70.29  ? 388  LEU   R C   1 
ATOM   4505 O  O   . LEU   B 2 491 ? 160.785 155.137 141.539 1.00 70.29  ? 388  LEU   R O   1 
ATOM   4506 C  CB  . LEU   B 2 491 ? 160.070 155.667 138.390 1.00 70.29  ? 388  LEU   R CB  1 
ATOM   4507 C  CG  . LEU   B 2 491 ? 160.562 157.042 138.832 1.00 70.29  ? 388  LEU   R CG  1 
ATOM   4508 C  CD1 . LEU   B 2 491 ? 162.078 157.094 138.760 1.00 70.29  ? 388  LEU   R CD1 1 
ATOM   4509 C  CD2 . LEU   B 2 491 ? 159.952 158.128 137.974 1.00 70.29  ? 388  LEU   R CD2 1 
ATOM   4510 N  N   . ASN   B 2 492 ? 158.809 154.210 140.982 1.00 69.34  ? 389  ASN   R N   1 
ATOM   4511 C  CA  . ASN   B 2 492 ? 158.314 154.202 142.357 1.00 69.34  ? 389  ASN   R CA  1 
ATOM   4512 C  C   . ASN   B 2 492 ? 159.130 153.259 143.228 1.00 69.34  ? 389  ASN   R C   1 
ATOM   4513 O  O   . ASN   B 2 492 ? 159.477 153.591 144.373 1.00 69.34  ? 389  ASN   R O   1 
ATOM   4514 C  CB  . ASN   B 2 492 ? 156.842 153.793 142.375 1.00 69.34  ? 389  ASN   R CB  1 
ATOM   4515 C  CG  . ASN   B 2 492 ? 156.254 153.788 143.769 1.00 69.34  ? 389  ASN   R CG  1 
ATOM   4516 O  OD1 . ASN   B 2 492 ? 156.664 154.559 144.633 1.00 69.34  ? 389  ASN   R OD1 1 
ATOM   4517 N  ND2 . ASN   B 2 492 ? 155.282 152.916 143.994 1.00 69.34  ? 389  ASN   R ND2 1 
ATOM   4518 N  N   . SER   B 2 493 ? 159.438 152.075 142.696 1.00 67.72  ? 390  SER   R N   1 
ATOM   4519 C  CA  . SER   B 2 493 ? 160.307 151.142 143.406 1.00 67.72  ? 390  SER   R CA  1 
ATOM   4520 C  C   . SER   B 2 493 ? 161.705 151.717 143.604 1.00 67.72  ? 390  SER   R C   1 
ATOM   4521 O  O   . SER   B 2 493 ? 162.376 151.388 144.587 1.00 67.72  ? 390  SER   R O   1 
ATOM   4522 C  CB  . SER   B 2 493 ? 160.380 149.819 142.648 1.00 67.72  ? 390  SER   R CB  1 
ATOM   4523 O  OG  . SER   B 2 493 ? 159.093 149.249 142.501 1.00 67.72  ? 390  SER   R OG  1 
ATOM   4524 N  N   . THR   B 2 494 ? 162.162 152.561 142.676 1.00 68.62  ? 391  THR   R N   1 
ATOM   4525 C  CA  . THR   B 2 494 ? 163.446 153.234 142.843 1.00 68.62  ? 391  THR   R CA  1 
ATOM   4526 C  C   . THR   B 2 494 ? 163.391 154.241 143.984 1.00 68.62  ? 391  THR   R C   1 
ATOM   4527 O  O   . THR   B 2 494 ? 164.279 154.278 144.841 1.00 68.62  ? 391  THR   R O   1 
ATOM   4528 C  CB  . THR   B 2 494 ? 163.844 153.948 141.548 1.00 68.62  ? 391  THR   R CB  1 
ATOM   4529 O  OG1 . THR   B 2 494 ? 163.953 153.009 140.479 1.00 68.62  ? 391  THR   R OG1 1 
ATOM   4530 C  CG2 . THR   B 2 494 ? 165.182 154.650 141.713 1.00 68.62  ? 391  THR   R CG2 1 
ATOM   4531 N  N   . VAL   B 2 495 ? 162.346 155.072 144.010 1.00 69.02  ? 392  VAL   R N   1 
ATOM   4532 C  CA  . VAL   B 2 495 ? 162.336 156.226 144.905 1.00 69.02  ? 392  VAL   R CA  1 
ATOM   4533 C  C   . VAL   B 2 495 ? 161.839 155.921 146.309 1.00 69.02  ? 392  VAL   R C   1 
ATOM   4534 O  O   . VAL   B 2 495 ? 162.005 156.767 147.201 1.00 69.02  ? 392  VAL   R O   1 
ATOM   4535 C  CB  . VAL   B 2 495 ? 161.487 157.377 144.333 1.00 69.02  ? 392  VAL   R CB  1 
ATOM   4536 C  CG1 . VAL   B 2 495 ? 162.039 157.825 142.994 1.00 69.02  ? 392  VAL   R CG1 1 
ATOM   4537 C  CG2 . VAL   B 2 495 ? 160.043 156.953 144.205 1.00 69.02  ? 392  VAL   R CG2 1 
ATOM   4538 N  N   . ASN   B 2 496 ? 161.215 154.764 146.540 1.00 67.16  ? 393  ASN   R N   1 
ATOM   4539 C  CA  . ASN   B 2 496 ? 160.800 154.432 147.905 1.00 67.16  ? 393  ASN   R CA  1 
ATOM   4540 C  C   . ASN   B 2 496 ? 161.960 154.266 148.897 1.00 67.16  ? 393  ASN   R C   1 
ATOM   4541 O  O   . ASN   B 2 496 ? 161.875 154.842 149.998 1.00 67.16  ? 393  ASN   R O   1 
ATOM   4542 C  CB  . ASN   B 2 496 ? 159.885 153.202 147.879 1.00 67.16  ? 393  ASN   R CB  1 
ATOM   4543 C  CG  . ASN   B 2 496 ? 158.425 153.573 147.795 1.00 67.16  ? 393  ASN   R CG  1 
ATOM   4544 O  OD1 . ASN   B 2 496 ? 157.964 154.473 148.489 1.00 67.16  ? 393  ASN   R OD1 1 
ATOM   4545 N  ND2 . ASN   B 2 496 ? 157.688 152.884 146.936 1.00 67.16  ? 393  ASN   R ND2 1 
ATOM   4546 N  N   . PRO   B 2 497 ? 163.041 153.512 148.612 1.00 68.75  ? 394  PRO   R N   1 
ATOM   4547 C  CA  . PRO   B 2 497 ? 164.147 153.456 149.587 1.00 68.75  ? 394  PRO   R CA  1 
ATOM   4548 C  C   . PRO   B 2 497 ? 164.852 154.781 149.803 1.00 68.75  ? 394  PRO   R C   1 
ATOM   4549 O  O   . PRO   B 2 497 ? 165.415 154.988 150.884 1.00 68.75  ? 394  PRO   R O   1 
ATOM   4550 C  CB  . PRO   B 2 497 ? 165.099 152.415 148.984 1.00 68.75  ? 394  PRO   R CB  1 
ATOM   4551 C  CG  . PRO   B 2 497 ? 164.244 151.596 148.120 1.00 68.75  ? 394  PRO   R CG  1 
ATOM   4552 C  CD  . PRO   B 2 497 ? 163.311 152.576 147.504 1.00 68.75  ? 394  PRO   R CD  1 
ATOM   4553 N  N   . ILE   B 2 498 ? 164.834 155.684 148.821 1.00 67.65  ? 395  ILE   R N   1 
ATOM   4554 C  CA  . ILE   B 2 498 ? 165.400 157.014 149.023 1.00 67.65  ? 395  ILE   R CA  1 
ATOM   4555 C  C   . ILE   B 2 498 ? 164.608 157.770 150.081 1.00 67.65  ? 395  ILE   R C   1 
ATOM   4556 O  O   . ILE   B 2 498 ? 165.184 158.426 150.956 1.00 67.65  ? 395  ILE   R O   1 
ATOM   4557 C  CB  . ILE   B 2 498 ? 165.447 157.783 147.691 1.00 67.65  ? 395  ILE   R CB  1 
ATOM   4558 C  CG1 . ILE   B 2 498 ? 166.123 156.936 146.613 1.00 67.65  ? 395  ILE   R CG1 1 
ATOM   4559 C  CG2 . ILE   B 2 498 ? 166.179 159.100 147.861 1.00 67.65  ? 395  ILE   R CG2 1 
ATOM   4560 C  CD1 . ILE   B 2 498 ? 167.550 156.564 146.934 1.00 67.65  ? 395  ILE   R CD1 1 
ATOM   4561 N  N   . ILE   B 2 499 ? 163.276 157.678 150.024 1.00 65.47  ? 396  ILE   R N   1 
ATOM   4562 C  CA  . ILE   B 2 499 ? 162.428 158.298 151.039 1.00 65.47  ? 396  ILE   R CA  1 
ATOM   4563 C  C   . ILE   B 2 499 ? 162.672 157.659 152.400 1.00 65.47  ? 396  ILE   R C   1 
ATOM   4564 O  O   . ILE   B 2 499 ? 162.746 158.354 153.424 1.00 65.47  ? 396  ILE   R O   1 
ATOM   4565 C  CB  . ILE   B 2 499 ? 160.949 158.202 150.624 1.00 65.47  ? 396  ILE   R CB  1 
ATOM   4566 C  CG1 . ILE   B 2 499 ? 160.715 158.950 149.315 1.00 65.47  ? 396  ILE   R CG1 1 
ATOM   4567 C  CG2 . ILE   B 2 499 ? 160.043 158.760 151.701 1.00 65.47  ? 396  ILE   R CG2 1 
ATOM   4568 C  CD1 . ILE   B 2 499 ? 159.330 158.760 148.751 1.00 65.47  ? 396  ILE   R CD1 1 
ATOM   4569 N  N   . TYR   B 2 500 ? 162.820 156.328 152.429 1.00 73.39  ? 397  TYR   R N   1 
ATOM   4570 C  CA  . TYR   B 2 500 ? 163.073 155.638 153.694 1.00 73.39  ? 397  TYR   R CA  1 
ATOM   4571 C  C   . TYR   B 2 500 ? 164.393 156.079 154.317 1.00 73.39  ? 397  TYR   R C   1 
ATOM   4572 O  O   . TYR   B 2 500 ? 164.483 156.264 155.536 1.00 73.39  ? 397  TYR   R O   1 
ATOM   4573 C  CB  . TYR   B 2 500 ? 163.088 154.121 153.498 1.00 73.39  ? 397  TYR   R CB  1 
ATOM   4574 C  CG  . TYR   B 2 500 ? 161.869 153.508 152.855 1.00 73.39  ? 397  TYR   R CG  1 
ATOM   4575 C  CD1 . TYR   B 2 500 ? 160.621 154.111 152.936 1.00 73.39  ? 397  TYR   R CD1 1 
ATOM   4576 C  CD2 . TYR   B 2 500 ? 161.971 152.306 152.173 1.00 73.39  ? 397  TYR   R CD2 1 
ATOM   4577 C  CE1 . TYR   B 2 500 ? 159.520 153.539 152.340 1.00 73.39  ? 397  TYR   R CE1 1 
ATOM   4578 C  CE2 . TYR   B 2 500 ? 160.880 151.729 151.577 1.00 73.39  ? 397  TYR   R CE2 1 
ATOM   4579 C  CZ  . TYR   B 2 500 ? 159.658 152.346 151.664 1.00 73.39  ? 397  TYR   R CZ  1 
ATOM   4580 O  OH  . TYR   B 2 500 ? 158.573 151.761 151.065 1.00 73.39  ? 397  TYR   R OH  1 
ATOM   4581 N  N   . ALA   B 2 501 ? 165.431 156.247 153.495 1.00 73.54  ? 398  ALA   R N   1 
ATOM   4582 C  CA  . ALA   B 2 501 ? 166.727 156.659 154.020 1.00 73.54  ? 398  ALA   R CA  1 
ATOM   4583 C  C   . ALA   B 2 501 ? 166.747 158.137 154.388 1.00 73.54  ? 398  ALA   R C   1 
ATOM   4584 O  O   . ALA   B 2 501 ? 167.473 158.534 155.306 1.00 73.54  ? 398  ALA   R O   1 
ATOM   4585 C  CB  . ALA   B 2 501 ? 167.826 156.350 153.007 1.00 73.54  ? 398  ALA   R CB  1 
ATOM   4586 N  N   . LEU   B 2 502 ? 165.973 158.965 153.686 1.00 71.72  ? 399  LEU   R N   1 
ATOM   4587 C  CA  . LEU   B 2 502 ? 165.979 160.394 153.969 1.00 71.72  ? 399  LEU   R CA  1 
ATOM   4588 C  C   . LEU   B 2 502 ? 165.183 160.733 155.221 1.00 71.72  ? 399  LEU   R C   1 
ATOM   4589 O  O   . LEU   B 2 502 ? 165.578 161.622 155.984 1.00 71.72  ? 399  LEU   R O   1 
ATOM   4590 C  CB  . LEU   B 2 502 ? 165.430 161.169 152.772 1.00 71.72  ? 399  LEU   R CB  1 
ATOM   4591 C  CG  . LEU   B 2 502 ? 166.425 161.530 151.670 1.00 71.72  ? 399  LEU   R CG  1 
ATOM   4592 C  CD1 . LEU   B 2 502 ? 165.834 162.587 150.755 1.00 71.72  ? 399  LEU   R CD1 1 
ATOM   4593 C  CD2 . LEU   B 2 502 ? 167.743 162.004 152.257 1.00 71.72  ? 399  LEU   R CD2 1 
ATOM   4594 N  N   . ARG   B 2 503 ? 164.067 160.043 155.457 1.00 67.06  ? 400  ARG   R N   1 
ATOM   4595 C  CA  . ARG   B 2 503 ? 163.186 160.441 156.548 1.00 67.06  ? 400  ARG   R CA  1 
ATOM   4596 C  C   . ARG   B 2 503 ? 163.557 159.800 157.881 1.00 67.06  ? 400  ARG   R C   1 
ATOM   4597 O  O   . ARG   B 2 503 ? 163.651 160.494 158.897 1.00 67.06  ? 400  ARG   R O   1 
ATOM   4598 C  CB  . ARG   B 2 503 ? 161.737 160.109 156.194 1.00 67.06  ? 400  ARG   R CB  1 
ATOM   4599 C  CG  . ARG   B 2 503 ? 161.176 160.956 155.073 1.00 67.06  ? 400  ARG   R CG  1 
ATOM   4600 C  CD  . ARG   B 2 503 ? 161.163 162.420 155.454 1.00 67.06  ? 400  ARG   R CD  1 
ATOM   4601 N  NE  . ARG   B 2 503 ? 160.202 162.702 156.512 1.00 67.06  ? 400  ARG   R NE  1 
ATOM   4602 C  CZ  . ARG   B 2 503 ? 160.006 163.899 157.045 1.00 67.06  ? 400  ARG   R CZ  1 
ATOM   4603 N  NH1 . ARG   B 2 503 ? 160.698 164.954 156.647 1.00 67.06  ? 400  ARG   R NH1 1 
ATOM   4604 N  NH2 . ARG   B 2 503 ? 159.095 164.042 158.003 1.00 67.06  ? 400  ARG   R NH2 1 
ATOM   4605 N  N   . SER   B 2 504 ? 163.770 158.488 157.901 1.00 78.41  ? 401  SER   R N   1 
ATOM   4606 C  CA  . SER   B 2 504 ? 163.902 157.764 159.159 1.00 78.41  ? 401  SER   R CA  1 
ATOM   4607 C  C   . SER   B 2 504 ? 165.312 157.913 159.719 1.00 78.41  ? 401  SER   R C   1 
ATOM   4608 O  O   . SER   B 2 504 ? 166.287 157.492 159.087 1.00 78.41  ? 401  SER   R O   1 
ATOM   4609 C  CB  . SER   B 2 504 ? 163.558 156.291 158.962 1.00 78.41  ? 401  SER   R CB  1 
ATOM   4610 O  OG  . SER   B 2 504 ? 163.479 155.619 160.206 1.00 78.41  ? 401  SER   R OG  1 
ATOM   4611 N  N   . LYS   B 2 505 ? 165.414 158.504 160.912 1.00 84.16  ? 402  LYS   R N   1 
ATOM   4612 C  CA  . LYS   B 2 505 ? 166.705 158.620 161.582 1.00 84.16  ? 402  LYS   R CA  1 
ATOM   4613 C  C   . LYS   B 2 505 ? 167.195 157.267 162.083 1.00 84.16  ? 402  LYS   R C   1 
ATOM   4614 O  O   . LYS   B 2 505 ? 168.396 156.979 162.030 1.00 84.16  ? 402  LYS   R O   1 
ATOM   4615 C  CB  . LYS   B 2 505 ? 166.603 159.616 162.737 1.00 84.16  ? 402  LYS   R CB  1 
ATOM   4616 C  CG  . LYS   B 2 505 ? 167.923 159.941 163.417 1.00 84.16  ? 402  LYS   R CG  1 
ATOM   4617 C  CD  . LYS   B 2 505 ? 168.969 160.412 162.422 1.00 84.16  ? 402  LYS   R CD  1 
ATOM   4618 C  CE  . LYS   B 2 505 ? 170.352 160.468 163.053 1.00 84.16  ? 402  LYS   R CE  1 
ATOM   4619 N  NZ  . LYS   B 2 505 ? 170.922 159.109 163.268 1.00 84.16  ? 402  LYS   R NZ  1 
ATOM   4620 N  N   . ASP   B 2 506 ? 166.280 156.430 162.581 1.00 85.80  ? 403  ASP   R N   1 
ATOM   4621 C  CA  . ASP   B 2 506 ? 166.666 155.118 163.094 1.00 85.80  ? 403  ASP   R CA  1 
ATOM   4622 C  C   . ASP   B 2 506 ? 167.174 154.211 161.981 1.00 85.80  ? 403  ASP   R C   1 
ATOM   4623 O  O   . ASP   B 2 506 ? 168.168 153.497 162.161 1.00 85.80  ? 403  ASP   R O   1 
ATOM   4624 C  CB  . ASP   B 2 506 ? 165.486 154.468 163.814 1.00 85.80  ? 403  ASP   R CB  1 
ATOM   4625 C  CG  . ASP   B 2 506 ? 164.906 155.353 164.895 1.00 85.80  ? 403  ASP   R CG  1 
ATOM   4626 O  OD1 . ASP   B 2 506 ? 164.295 156.388 164.553 1.00 85.80  ? 403  ASP   R OD1 1 
ATOM   4627 O  OD2 . ASP   B 2 506 ? 165.059 155.014 166.087 1.00 85.80  ? 403  ASP   R OD2 1 
ATOM   4628 N  N   . LEU   B 2 507 ? 166.508 154.230 160.823 1.00 81.44  ? 404  LEU   R N   1 
ATOM   4629 C  CA  . LEU   B 2 507 ? 166.977 153.450 159.682 1.00 81.44  ? 404  LEU   R CA  1 
ATOM   4630 C  C   . LEU   B 2 507 ? 168.324 153.956 159.183 1.00 81.44  ? 404  LEU   R C   1 
ATOM   4631 O  O   . LEU   B 2 507 ? 169.193 153.159 158.809 1.00 81.44  ? 404  LEU   R O   1 
ATOM   4632 C  CB  . LEU   B 2 507 ? 165.941 153.492 158.563 1.00 81.44  ? 404  LEU   R CB  1 
ATOM   4633 C  CG  . LEU   B 2 507 ? 166.307 152.753 157.277 1.00 81.44  ? 404  LEU   R CG  1 
ATOM   4634 C  CD1 . LEU   B 2 507 ? 166.403 151.261 157.525 1.00 81.44  ? 404  LEU   R CD1 1 
ATOM   4635 C  CD2 . LEU   B 2 507 ? 165.295 153.051 156.198 1.00 81.44  ? 404  LEU   R CD2 1 
ATOM   4636 N  N   . ARG   B 2 508 ? 168.513 155.279 159.177 1.00 83.92  ? 405  ARG   R N   1 
ATOM   4637 C  CA  . ARG   B 2 508 ? 169.793 155.852 158.777 1.00 83.92  ? 405  ARG   R CA  1 
ATOM   4638 C  C   . ARG   B 2 508 ? 170.906 155.419 159.721 1.00 83.92  ? 405  ARG   R C   1 
ATOM   4639 O  O   . ARG   B 2 508 ? 172.010 155.076 159.279 1.00 83.92  ? 405  ARG   R O   1 
ATOM   4640 C  CB  . ARG   B 2 508 ? 169.694 157.376 158.744 1.00 83.92  ? 405  ARG   R CB  1 
ATOM   4641 C  CG  . ARG   B 2 508 ? 170.934 158.060 158.204 1.00 83.92  ? 405  ARG   R CG  1 
ATOM   4642 C  CD  . ARG   B 2 508 ? 170.810 159.576 158.238 1.00 83.92  ? 405  ARG   R CD  1 
ATOM   4643 N  NE  . ARG   B 2 508 ? 169.734 160.082 157.396 1.00 83.92  ? 405  ARG   R NE  1 
ATOM   4644 C  CZ  . ARG   B 2 508 ? 168.653 160.695 157.857 1.00 83.92  ? 405  ARG   R CZ  1 
ATOM   4645 N  NH1 . ARG   B 2 508 ? 168.472 160.897 159.150 1.00 83.92  ? 405  ARG   R NH1 1 
ATOM   4646 N  NH2 . ARG   B 2 508 ? 167.734 161.125 156.999 1.00 83.92  ? 405  ARG   R NH2 1 
ATOM   4647 N  N   . HIS   B 2 509 ? 170.628 155.415 161.027 1.00 87.58  ? 406  HIS   R N   1 
ATOM   4648 C  CA  . HIS   B 2 509 ? 171.630 154.996 161.999 1.00 87.58  ? 406  HIS   R CA  1 
ATOM   4649 C  C   . HIS   B 2 509 ? 171.917 153.503 161.904 1.00 87.58  ? 406  HIS   R C   1 
ATOM   4650 O  O   . HIS   B 2 509 ? 173.057 153.079 162.124 1.00 87.58  ? 406  HIS   R O   1 
ATOM   4651 C  CB  . HIS   B 2 509 ? 171.176 155.360 163.411 1.00 87.58  ? 406  HIS   R CB  1 
ATOM   4652 C  CG  . HIS   B 2 509 ? 172.166 154.999 164.471 1.00 87.58  ? 406  HIS   R CG  1 
ATOM   4653 N  ND1 . HIS   B 2 509 ? 173.333 155.705 164.669 1.00 87.58  ? 406  HIS   R ND1 1 
ATOM   4654 C  CD2 . HIS   B 2 509 ? 172.170 154.000 165.385 1.00 87.58  ? 406  HIS   R CD2 1 
ATOM   4655 C  CE1 . HIS   B 2 509 ? 174.011 155.160 165.663 1.00 87.58  ? 406  HIS   R CE1 1 
ATOM   4656 N  NE2 . HIS   B 2 509 ? 173.328 154.124 166.115 1.00 87.58  ? 406  HIS   R NE2 1 
ATOM   4657 N  N   . ALA   B 2 510 ? 170.900 152.696 161.592 1.00 84.94  ? 407  ALA   R N   1 
ATOM   4658 C  CA  . ALA   B 2 510 ? 171.128 151.270 161.383 1.00 84.94  ? 407  ALA   R CA  1 
ATOM   4659 C  C   . ALA   B 2 510 ? 171.974 151.022 160.142 1.00 84.94  ? 407  ALA   R C   1 
ATOM   4660 O  O   . ALA   B 2 510 ? 172.837 150.138 160.139 1.00 84.94  ? 407  ALA   R O   1 
ATOM   4661 C  CB  . ALA   B 2 510 ? 169.794 150.533 161.280 1.00 84.94  ? 407  ALA   R CB  1 
ATOM   4662 N  N   . PHE   B 2 511 ? 171.736 151.790 159.076 1.00 86.13  ? 408  PHE   R N   1 
ATOM   4663 C  CA  . PHE   B 2 511 ? 172.547 151.652 157.870 1.00 86.13  ? 408  PHE   R CA  1 
ATOM   4664 C  C   . PHE   B 2 511 ? 173.980 152.105 158.113 1.00 86.13  ? 408  PHE   R C   1 
ATOM   4665 O  O   . PHE   B 2 511 ? 174.922 151.518 157.569 1.00 86.13  ? 408  PHE   R O   1 
ATOM   4666 C  CB  . PHE   B 2 511 ? 171.927 152.442 156.720 1.00 86.13  ? 408  PHE   R CB  1 
ATOM   4667 C  CG  . PHE   B 2 511 ? 172.778 152.472 155.486 1.00 86.13  ? 408  PHE   R CG  1 
ATOM   4668 C  CD1 . PHE   B 2 511 ? 172.991 151.318 154.749 1.00 86.13  ? 408  PHE   R CD1 1 
ATOM   4669 C  CD2 . PHE   B 2 511 ? 173.372 153.651 155.066 1.00 86.13  ? 408  PHE   R CD2 1 
ATOM   4670 C  CE1 . PHE   B 2 511 ? 173.777 151.338 153.615 1.00 86.13  ? 408  PHE   R CE1 1 
ATOM   4671 C  CE2 . PHE   B 2 511 ? 174.161 153.678 153.932 1.00 86.13  ? 408  PHE   R CE2 1 
ATOM   4672 C  CZ  . PHE   B 2 511 ? 174.363 152.519 153.206 1.00 86.13  ? 408  PHE   R CZ  1 
ATOM   4673 N  N   . ARG   B 2 512 ? 174.168 153.145 158.925 1.00 91.88  ? 409  ARG   R N   1 
ATOM   4674 C  CA  . ARG   B 2 512 ? 175.511 153.581 159.281 1.00 91.88  ? 409  ARG   R CA  1 
ATOM   4675 C  C   . ARG   B 2 512 ? 176.180 152.663 160.294 1.00 91.88  ? 409  ARG   R C   1 
ATOM   4676 O  O   . ARG   B 2 512 ? 177.376 152.826 160.556 1.00 91.88  ? 409  ARG   R O   1 
ATOM   4677 C  CB  . ARG   B 2 512 ? 175.481 155.011 159.828 1.00 91.88  ? 409  ARG   R CB  1 
ATOM   4678 C  CG  . ARG   B 2 512 ? 175.626 156.092 158.762 1.00 91.88  ? 409  ARG   R CG  1 
ATOM   4679 C  CD  . ARG   B 2 512 ? 177.041 156.661 158.715 1.00 91.88  ? 409  ARG   R CD  1 
ATOM   4680 N  NE  . ARG   B 2 512 ? 177.115 157.867 157.897 1.00 91.88  ? 409  ARG   R NE  1 
ATOM   4681 C  CZ  . ARG   B 2 512 ? 178.242 158.461 157.529 1.00 91.88  ? 409  ARG   R CZ  1 
ATOM   4682 N  NH1 . ARG   B 2 512 ? 179.424 157.988 157.890 1.00 91.88  ? 409  ARG   R NH1 1 
ATOM   4683 N  NH2 . ARG   B 2 512 ? 178.183 159.558 156.778 1.00 91.88  ? 409  ARG   R NH2 1 
ATOM   4684 N  N   . SER   B 2 513 ? 175.444 151.715 160.873 1.00 92.28  ? 410  SER   R N   1 
ATOM   4685 C  CA  . SER   B 2 513 ? 176.032 150.778 161.817 1.00 92.28  ? 410  SER   R CA  1 
ATOM   4686 C  C   . SER   B 2 513 ? 176.717 149.601 161.137 1.00 92.28  ? 410  SER   R C   1 
ATOM   4687 O  O   . SER   B 2 513 ? 177.491 148.894 161.789 1.00 92.28  ? 410  SER   R O   1 
ATOM   4688 C  CB  . SER   B 2 513 ? 174.960 150.260 162.775 1.00 92.28  ? 410  SER   R CB  1 
ATOM   4689 O  OG  . SER   B 2 513 ? 174.387 151.326 163.510 1.00 92.28  ? 410  SER   R OG  1 
ATOM   4690 N  N   . MET   B 2 514 ? 176.453 149.372 159.851 1.00 94.03  ? 411  MET   R N   1 
ATOM   4691 C  CA  . MET   B 2 514 ? 177.059 148.234 159.169 1.00 94.03  ? 411  MET   R CA  1 
ATOM   4692 C  C   . MET   B 2 514 ? 178.519 148.489 158.819 1.00 94.03  ? 411  MET   R C   1 
ATOM   4693 O  O   . MET   B 2 514 ? 179.343 147.571 158.884 1.00 94.03  ? 411  MET   R O   1 
ATOM   4694 C  CB  . MET   B 2 514 ? 176.254 147.887 157.918 1.00 94.03  ? 411  MET   R CB  1 
ATOM   4695 C  CG  . MET   B 2 514 ? 174.838 147.388 158.199 1.00 94.03  ? 411  MET   R CG  1 
ATOM   4696 S  SD  . MET   B 2 514 ? 174.770 145.859 159.164 1.00 94.03  ? 411  MET   R SD  1 
ATOM   4697 C  CE  . MET   B 2 514 ? 174.345 146.448 160.805 1.00 94.03  ? 411  MET   R CE  1 
ATOM   4698 N  N   . PHE   B 2 515 ? 178.862 149.718 158.454 1.00 94.35  ? 412  PHE   R N   1 
ATOM   4699 C  CA  . PHE   B 2 515 ? 180.244 150.036 158.123 1.00 94.35  ? 412  PHE   R CA  1 
ATOM   4700 C  C   . PHE   B 2 515 ? 180.946 150.674 159.319 1.00 94.35  ? 412  PHE   R C   1 
ATOM   4701 O  O   . PHE   B 2 515 ? 180.550 150.466 160.467 1.00 94.35  ? 412  PHE   R O   1 
ATOM   4702 C  CB  . PHE   B 2 515 ? 180.307 150.962 156.906 1.00 94.35  ? 412  PHE   R CB  1 
ATOM   4703 C  CG  . PHE   B 2 515 ? 181.707 151.302 156.475 1.00 94.35  ? 412  PHE   R CG  1 
ATOM   4704 C  CD1 . PHE   B 2 515 ? 182.478 150.374 155.790 1.00 94.35  ? 412  PHE   R CD1 1 
ATOM   4705 C  CD2 . PHE   B 2 515 ? 182.251 152.547 156.748 1.00 94.35  ? 412  PHE   R CD2 1 
ATOM   4706 C  CE1 . PHE   B 2 515 ? 183.765 150.680 155.390 1.00 94.35  ? 412  PHE   R CE1 1 
ATOM   4707 C  CE2 . PHE   B 2 515 ? 183.538 152.860 156.351 1.00 94.35  ? 412  PHE   R CE2 1 
ATOM   4708 C  CZ  . PHE   B 2 515 ? 184.296 151.924 155.670 1.00 94.35  ? 412  PHE   R CZ  1 
HETATM 4709 N  N3  . A1AKO C 3 .   ? 156.946 147.695 129.320 1.00 87.68  ? 1201 A1AKO R N3  1 
HETATM 4710 C  C4  . A1AKO C 3 .   ? 155.848 147.123 129.818 1.00 87.68  ? 1201 A1AKO R C4  1 
HETATM 4711 C  C7  . A1AKO C 3 .   ? 154.186 147.032 132.846 1.00 87.68  ? 1201 A1AKO R C7  1 
HETATM 4712 C  C8  . A1AKO C 3 .   ? 152.886 146.899 133.526 1.00 87.68  ? 1201 A1AKO R C8  1 
HETATM 4713 C  C10 . A1AKO C 3 .   ? 151.408 147.480 135.342 1.00 87.68  ? 1201 A1AKO R C10 1 
HETATM 4714 C  C13 . A1AKO C 3 .   ? 150.687 145.917 133.669 1.00 87.68  ? 1201 A1AKO R C13 1 
HETATM 4715 C  C15 . A1AKO C 3 .   ? 155.421 147.653 133.446 1.00 87.68  ? 1201 A1AKO R C15 1 
HETATM 4716 C  C17 . A1AKO C 3 .   ? 156.165 145.382 134.255 1.00 87.68  ? 1201 A1AKO R C17 1 
HETATM 4717 C  C20 . A1AKO C 3 .   ? 157.006 146.408 136.671 1.00 87.68  ? 1201 A1AKO R C20 1 
HETATM 4718 C  C21 . A1AKO C 3 .   ? 156.475 147.249 135.709 1.00 87.68  ? 1201 A1AKO R C21 1 
HETATM 4719 C  C22 . A1AKO C 3 .   ? 156.297 147.816 132.191 1.00 87.68  ? 1201 A1AKO R C22 1 
HETATM 4720 C  C24 . A1AKO C 3 .   ? 153.944 146.883 128.472 1.00 87.68  ? 1201 A1AKO R C24 1 
HETATM 4721 C  C26 . A1AKO C 3 .   ? 153.072 146.008 127.640 1.00 87.68  ? 1201 A1AKO R C26 1 
HETATM 4722 C  C28 . A1AKO C 3 .   ? 159.824 148.664 128.364 1.00 87.68  ? 1201 A1AKO R C28 1 
HETATM 4723 C  C11 . A1AKO C 3 .   ? 150.455 146.634 134.822 1.00 87.68  ? 1201 A1AKO R C11 1 
HETATM 4724 C  C14 . A1AKO C 3 .   ? 151.903 146.052 133.023 1.00 87.68  ? 1201 A1AKO R C14 1 
HETATM 4725 C  C16 . A1AKO C 3 .   ? 156.047 146.744 134.489 1.00 87.68  ? 1201 A1AKO R C16 1 
HETATM 4726 C  C18 . A1AKO C 3 .   ? 156.696 144.544 135.219 1.00 87.68  ? 1201 A1AKO R C18 1 
HETATM 4727 C  C19 . A1AKO C 3 .   ? 157.116 145.057 136.427 1.00 87.68  ? 1201 A1AKO R C19 1 
HETATM 4728 C  C27 . A1AKO C 3 .   ? 158.587 148.901 127.784 1.00 87.68  ? 1201 A1AKO R C27 1 
HETATM 4729 C  C29 . A1AKO C 3 .   ? 160.742 149.696 128.447 1.00 87.68  ? 1201 A1AKO R C29 1 
HETATM 4730 C  C30 . A1AKO C 3 .   ? 160.440 150.962 127.956 1.00 87.68  ? 1201 A1AKO R C30 1 
HETATM 4731 C  C31 . A1AKO C 3 .   ? 161.419 152.084 128.084 1.00 87.68  ? 1201 A1AKO R C31 1 
HETATM 4732 C  C35 . A1AKO C 3 .   ? 159.196 151.175 127.376 1.00 87.68  ? 1201 A1AKO R C35 1 
HETATM 4733 C  C36 . A1AKO C 3 .   ? 158.268 150.153 127.286 1.00 87.68  ? 1201 A1AKO R C36 1 
HETATM 4734 C  C9  . A1AKO C 3 .   ? 152.623 147.610 134.692 1.00 87.68  ? 1201 A1AKO R C9  1 
HETATM 4735 F  F32 . A1AKO C 3 .   ? 160.964 153.075 128.847 1.00 87.68  ? 1201 A1AKO R F32 1 
HETATM 4736 F  F33 . A1AKO C 3 .   ? 161.714 152.639 126.913 1.00 87.68  ? 1201 A1AKO R F33 1 
HETATM 4737 F  F34 . A1AKO C 3 .   ? 162.574 151.698 128.620 1.00 87.68  ? 1201 A1AKO R F34 1 
HETATM 4738 N  N23 . A1AKO C 3 .   ? 155.010 146.376 129.044 1.00 87.68  ? 1201 A1AKO R N23 1 
HETATM 4739 N  N25 . A1AKO C 3 .   ? 153.577 148.160 128.580 1.00 87.68  ? 1201 A1AKO R N25 1 
HETATM 4740 N  N5  . A1AKO C 3 .   ? 155.499 147.175 131.150 1.00 87.68  ? 1201 A1AKO R N5  1 
HETATM 4741 N  N6  . A1AKO C 3 .   ? 154.347 146.625 131.633 1.00 87.68  ? 1201 A1AKO R N6  1 
HETATM 4742 O  O1  . A1AKO C 3 .   ? 158.033 146.382 127.518 1.00 87.68  ? 1201 A1AKO R O1  1 
HETATM 4743 O  O37 . A1AKO C 3 .   ? 156.322 148.030 126.877 1.00 87.68  ? 1201 A1AKO R O37 1 
HETATM 4744 S  S2  . A1AKO C 3 .   ? 157.370 147.630 127.775 1.00 87.68  ? 1201 A1AKO R S2  1 
HETATM 4745 CL CL1 . A1AKO C 3 .   ? 148.925 146.468 135.638 1.00 87.68  ? 1201 A1AKO R CL1 1 
# 
