data_9B8H
# 
_entry.id   9B8H 
# 
_audit_conform.dict_name       mmcif_pdbx.dic 
_audit_conform.dict_version    5.403 
_audit_conform.dict_location   http://mmcif.pdb.org/dictionaries/ascii/mmcif_pdbx.dic 
# 
loop_
_database_2.database_id 
_database_2.database_code 
_database_2.pdbx_database_accession 
_database_2.pdbx_DOI 
PDB   9B8H         pdb_00009b8h 10.2210/pdb9b8h/pdb 
WWPDB D_1000282869 ?            ?                   
EMDB  EMD-44345    ?            ?                   
# 
loop_
_pdbx_audit_revision_history.ordinal 
_pdbx_audit_revision_history.data_content_type 
_pdbx_audit_revision_history.major_revision 
_pdbx_audit_revision_history.minor_revision 
_pdbx_audit_revision_history.revision_date 
_pdbx_audit_revision_history.part_number 
1 'Structure model' 1 0 2025-02-19 ? 
2 'EM metadata'     1 0 2025-02-19 ? 
3 FSC               1 0 2025-02-19 ? 
4 'Half map'        1 0 2025-02-19 1 
5 'Half map'        1 0 2025-02-19 2 
6 Image             1 0 2025-02-19 ? 
7 'Primary map'     1 0 2025-02-19 ? 
8 'Structure model' 1 1 2025-05-28 ? 
9 'EM metadata'     1 1 2025-05-28 ? 
# 
loop_
_pdbx_audit_revision_details.ordinal 
_pdbx_audit_revision_details.revision_ordinal 
_pdbx_audit_revision_details.data_content_type 
_pdbx_audit_revision_details.provider 
_pdbx_audit_revision_details.type 
_pdbx_audit_revision_details.description 
_pdbx_audit_revision_details.details 
1 1 'Structure model' repository 'Initial release' ? ? 
2 2 'EM metadata'     repository 'Initial release' ? ? 
3 3 FSC               repository 'Initial release' ? ? 
4 4 'Half map'        repository 'Initial release' ? ? 
5 5 'Half map'        repository 'Initial release' ? ? 
6 6 Image             repository 'Initial release' ? ? 
7 7 'Primary map'     repository 'Initial release' ? ? 
# 
loop_
_pdbx_audit_revision_group.ordinal 
_pdbx_audit_revision_group.revision_ordinal 
_pdbx_audit_revision_group.data_content_type 
_pdbx_audit_revision_group.group 
1 8 'Structure model' 'Data collection'      
2 9 'EM metadata'     'Data processing'      
3 9 'EM metadata'     'Experimental summary' 
# 
loop_
_pdbx_audit_revision_category.ordinal 
_pdbx_audit_revision_category.revision_ordinal 
_pdbx_audit_revision_category.data_content_type 
_pdbx_audit_revision_category.category 
1 8 'Structure model' em_admin    
2 8 'Structure model' em_software 
3 9 'EM metadata'     em_admin    
4 9 'EM metadata'     em_software 
# 
loop_
_pdbx_audit_revision_item.ordinal 
_pdbx_audit_revision_item.revision_ordinal 
_pdbx_audit_revision_item.data_content_type 
_pdbx_audit_revision_item.item 
1 8 'Structure model' '_em_admin.last_update' 
2 8 'Structure model' '_em_software.name'     
3 9 'EM metadata'     '_em_admin.last_update' 
4 9 'EM metadata'     '_em_software.name'     
# 
_pdbx_database_status.status_code                     REL 
_pdbx_database_status.status_code_sf                  ? 
_pdbx_database_status.status_code_mr                  ? 
_pdbx_database_status.entry_id                        9B8H 
_pdbx_database_status.recvd_initial_deposition_date   2024-03-30 
_pdbx_database_status.SG_entry                        N 
_pdbx_database_status.deposit_site                    RCSB 
_pdbx_database_status.process_site                    RCSB 
_pdbx_database_status.status_code_cs                  ? 
_pdbx_database_status.status_code_nmr_data            ? 
_pdbx_database_status.methods_development_category    ? 
_pdbx_database_status.pdb_format_compatible           N 
# 
loop_
_pdbx_database_related.db_name 
_pdbx_database_related.details 
_pdbx_database_related.db_id 
_pdbx_database_related.content_type 
EMDB 'Cryo-EM structure of E. coli cellulose synthase subunit C with cellotetraose' EMD-44345 'associated EM volume' 
PDB  'Cryo-EM structure of E. coli cellulose synthase subunit C'                    9B8A      unspecified            
# 
_pdbx_contact_author.id                 2 
_pdbx_contact_author.email              jz3x@virginia.edu 
_pdbx_contact_author.name_first         Jochen 
_pdbx_contact_author.name_last          Zimmer 
_pdbx_contact_author.name_mi            ? 
_pdbx_contact_author.role               'principal investigator/group leader' 
_pdbx_contact_author.identifier_ORCID   0000-0002-8423-2882 
# 
loop_
_audit_author.name 
_audit_author.pdbx_ordinal 
_audit_author.identifier_ORCID 
'Verma, P.'  1 0000-0003-3972-0112 
'Zimmer, J.' 2 0000-0002-8423-2882 
# 
_citation.abstract                  ? 
_citation.abstract_id_CAS           ? 
_citation.book_id_ISBN              ? 
_citation.book_publisher            ? 
_citation.book_publisher_city       ? 
_citation.book_title                ? 
_citation.coordinate_linkage        ? 
_citation.country                   UK 
_citation.database_id_Medline       ? 
_citation.details                   ? 
_citation.id                        primary 
_citation.journal_abbrev            'Nat Commun' 
_citation.journal_id_ASTM           ? 
_citation.journal_id_CSD            ? 
_citation.journal_id_ISSN           2041-1723 
_citation.journal_full              ? 
_citation.journal_issue             ? 
_citation.journal_volume            15 
_citation.language                  ? 
_citation.page_first                7798 
_citation.page_last                 7798 
_citation.title                     
'Insights into phosphoethanolamine cellulose synthesis and secretion across the Gram-negative cell envelope.' 
_citation.year                      2024 
_citation.database_id_CSD           ? 
_citation.pdbx_database_id_DOI      10.1038/s41467-024-51838-0 
_citation.pdbx_database_id_PubMed   39242554 
_citation.pdbx_database_id_patent   ? 
_citation.unpublished_flag          ? 
# 
loop_
_citation_author.citation_id 
_citation_author.name 
_citation_author.ordinal 
_citation_author.identifier_ORCID 
primary 'Verma, P.'      1 0000-0003-3972-0112 
primary 'Ho, R.'         2 ?                   
primary 'Chambers, S.A.' 3 0000-0002-3557-830X 
primary 'Cegelski, L.'   4 0000-0002-0978-1814 
primary 'Zimmer, J.'     5 0000-0002-8423-2882 
# 
loop_
_entity.id 
_entity.type 
_entity.src_method 
_entity.pdbx_description 
_entity.formula_weight 
_entity.pdbx_number_of_molecules 
_entity.pdbx_ec 
_entity.pdbx_mutation 
_entity.pdbx_fragment 
_entity.details 
1 polymer  man 'Cellulose synthase operon protein C'                                                                   126827.016 
1 ? ? ? ? 
2 branched syn 'beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose-(1-4)-beta-D-glucopyranose' 666.578    
1 ? ? ? ? 
# 
_entity_name_com.entity_id   1 
_entity_name_com.name        'Bacterial cellulose synthase subunit C, BcsC' 
# 
_entity_poly.entity_id                      1 
_entity_poly.type                           'polypeptide(L)' 
_entity_poly.nstd_linkage                   no 
_entity_poly.nstd_monomer                   no 
_entity_poly.pdbx_seq_one_letter_code       
;MHHHHHHHHVEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQL
APSSNAYKSSRTTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLK
RINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVSALKKYLSIFSDGDSV
AAAQSQLAEQQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALA
LDPHSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQT
LRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALD
PGSVWITYRLSQDLWQAGQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQELVNRL
QSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARAAYQNVLTREPANADAILGLTEVDIAAG
DKAAARSQLAKLPATDNASLNTQRRVALAQAQLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQAL
ETYKDAMVASGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGTGGYSDLKAHTTML
QVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNV
VDVVGGISYSDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLT
GKNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEYLSFAIPVMWRERTENWSWELG
ASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLL
YVRYSAAGWQGDMDLPPQPLIPYADW
;
_entity_poly.pdbx_seq_one_letter_code_can   
;MHHHHHHHHVEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQL
APSSNAYKSSRTTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLK
RINADAPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVSALKKYLSIFSDGDSV
AAAQSQLAEQQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALA
LDPHSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQT
LRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALD
PGSVWITYRLSQDLWQAGQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQELVNRL
QSDQVLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARAAYQNVLTREPANADAILGLTEVDIAAG
DKAAARSQLAKLPATDNASLNTQRRVALAQAQLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQAL
ETYKDAMVASGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGTGGYSDLKAHTTML
QVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNV
VDVVGGISYSDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLT
GKNVEDNWRVRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEYLSFAIPVMWRERTENWSWELG
ASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLL
YVRYSAAGWQGDMDLPPQPLIPYADW
;
_entity_poly.pdbx_strand_id                 A 
_entity_poly.pdbx_target_identifier         ? 
# 
loop_
_entity_poly_seq.entity_id 
_entity_poly_seq.num 
_entity_poly_seq.mon_id 
_entity_poly_seq.hetero 
1 1    MET n 
1 2    HIS n 
1 3    HIS n 
1 4    HIS n 
1 5    HIS n 
1 6    HIS n 
1 7    HIS n 
1 8    HIS n 
1 9    HIS n 
1 10   VAL n 
1 11   GLU n 
1 12   ALA n 
1 13   ALA n 
1 14   PRO n 
1 15   THR n 
1 16   ALA n 
1 17   GLN n 
1 18   GLN n 
1 19   GLN n 
1 20   LEU n 
1 21   LEU n 
1 22   GLU n 
1 23   GLN n 
1 24   VAL n 
1 25   ARG n 
1 26   LEU n 
1 27   GLY n 
1 28   GLU n 
1 29   ALA n 
1 30   THR n 
1 31   HIS n 
1 32   ARG n 
1 33   GLU n 
1 34   ASP n 
1 35   LEU n 
1 36   VAL n 
1 37   GLN n 
1 38   GLN n 
1 39   SER n 
1 40   LEU n 
1 41   TYR n 
1 42   ARG n 
1 43   LEU n 
1 44   GLU n 
1 45   LEU n 
1 46   ILE n 
1 47   ASP n 
1 48   PRO n 
1 49   ASN n 
1 50   ASN n 
1 51   PRO n 
1 52   ASP n 
1 53   VAL n 
1 54   VAL n 
1 55   ALA n 
1 56   ALA n 
1 57   ARG n 
1 58   PHE n 
1 59   ARG n 
1 60   SER n 
1 61   LEU n 
1 62   LEU n 
1 63   ARG n 
1 64   GLN n 
1 65   GLY n 
1 66   ASP n 
1 67   ILE n 
1 68   ASP n 
1 69   GLY n 
1 70   ALA n 
1 71   GLN n 
1 72   LYS n 
1 73   GLN n 
1 74   LEU n 
1 75   ASP n 
1 76   ARG n 
1 77   LEU n 
1 78   SER n 
1 79   GLN n 
1 80   LEU n 
1 81   ALA n 
1 82   PRO n 
1 83   SER n 
1 84   SER n 
1 85   ASN n 
1 86   ALA n 
1 87   TYR n 
1 88   LYS n 
1 89   SER n 
1 90   SER n 
1 91   ARG n 
1 92   THR n 
1 93   THR n 
1 94   MET n 
1 95   LEU n 
1 96   LEU n 
1 97   SER n 
1 98   THR n 
1 99   PRO n 
1 100  ASP n 
1 101  GLY n 
1 102  ARG n 
1 103  GLN n 
1 104  ALA n 
1 105  LEU n 
1 106  GLN n 
1 107  GLN n 
1 108  ALA n 
1 109  ARG n 
1 110  LEU n 
1 111  GLN n 
1 112  ALA n 
1 113  THR n 
1 114  THR n 
1 115  GLY n 
1 116  HIS n 
1 117  ALA n 
1 118  GLU n 
1 119  GLU n 
1 120  ALA n 
1 121  VAL n 
1 122  ALA n 
1 123  SER n 
1 124  TYR n 
1 125  ASN n 
1 126  LYS n 
1 127  LEU n 
1 128  PHE n 
1 129  ASN n 
1 130  GLY n 
1 131  ALA n 
1 132  PRO n 
1 133  PRO n 
1 134  GLU n 
1 135  GLY n 
1 136  ASP n 
1 137  ILE n 
1 138  ALA n 
1 139  VAL n 
1 140  GLU n 
1 141  TYR n 
1 142  TRP n 
1 143  SER n 
1 144  THR n 
1 145  VAL n 
1 146  ALA n 
1 147  LYS n 
1 148  ILE n 
1 149  PRO n 
1 150  ALA n 
1 151  ARG n 
1 152  ARG n 
1 153  GLY n 
1 154  GLU n 
1 155  ALA n 
1 156  ILE n 
1 157  ASN n 
1 158  GLN n 
1 159  LEU n 
1 160  LYS n 
1 161  ARG n 
1 162  ILE n 
1 163  ASN n 
1 164  ALA n 
1 165  ASP n 
1 166  ALA n 
1 167  PRO n 
1 168  GLY n 
1 169  ASN n 
1 170  THR n 
1 171  GLY n 
1 172  LEU n 
1 173  GLN n 
1 174  ASN n 
1 175  ASN n 
1 176  LEU n 
1 177  ALA n 
1 178  LEU n 
1 179  LEU n 
1 180  LEU n 
1 181  PHE n 
1 182  SER n 
1 183  SER n 
1 184  ASP n 
1 185  ARG n 
1 186  ARG n 
1 187  ASP n 
1 188  GLU n 
1 189  GLY n 
1 190  PHE n 
1 191  ALA n 
1 192  VAL n 
1 193  LEU n 
1 194  GLU n 
1 195  GLN n 
1 196  MET n 
1 197  ALA n 
1 198  LYS n 
1 199  SER n 
1 200  ASN n 
1 201  ALA n 
1 202  GLY n 
1 203  ARG n 
1 204  GLU n 
1 205  GLY n 
1 206  ALA n 
1 207  SER n 
1 208  LYS n 
1 209  ILE n 
1 210  TRP n 
1 211  TYR n 
1 212  GLY n 
1 213  GLN n 
1 214  ILE n 
1 215  LYS n 
1 216  ASP n 
1 217  MET n 
1 218  PRO n 
1 219  VAL n 
1 220  SER n 
1 221  ASP n 
1 222  ALA n 
1 223  SER n 
1 224  VAL n 
1 225  SER n 
1 226  ALA n 
1 227  LEU n 
1 228  LYS n 
1 229  LYS n 
1 230  TYR n 
1 231  LEU n 
1 232  SER n 
1 233  ILE n 
1 234  PHE n 
1 235  SER n 
1 236  ASP n 
1 237  GLY n 
1 238  ASP n 
1 239  SER n 
1 240  VAL n 
1 241  ALA n 
1 242  ALA n 
1 243  ALA n 
1 244  GLN n 
1 245  SER n 
1 246  GLN n 
1 247  LEU n 
1 248  ALA n 
1 249  GLU n 
1 250  GLN n 
1 251  GLN n 
1 252  LYS n 
1 253  GLN n 
1 254  LEU n 
1 255  ALA n 
1 256  ASP n 
1 257  PRO n 
1 258  ALA n 
1 259  PHE n 
1 260  ARG n 
1 261  ALA n 
1 262  ARG n 
1 263  ALA n 
1 264  GLN n 
1 265  GLY n 
1 266  LEU n 
1 267  ALA n 
1 268  ALA n 
1 269  VAL n 
1 270  ASP n 
1 271  SER n 
1 272  GLY n 
1 273  MET n 
1 274  ALA n 
1 275  GLY n 
1 276  LYS n 
1 277  ALA n 
1 278  ILE n 
1 279  PRO n 
1 280  GLU n 
1 281  LEU n 
1 282  GLN n 
1 283  GLN n 
1 284  ALA n 
1 285  VAL n 
1 286  ARG n 
1 287  ALA n 
1 288  ASN n 
1 289  PRO n 
1 290  LYS n 
1 291  ASP n 
1 292  SER n 
1 293  GLU n 
1 294  ALA n 
1 295  LEU n 
1 296  GLY n 
1 297  ALA n 
1 298  LEU n 
1 299  GLY n 
1 300  GLN n 
1 301  ALA n 
1 302  TYR n 
1 303  SER n 
1 304  GLN n 
1 305  LYS n 
1 306  GLY n 
1 307  ASP n 
1 308  ARG n 
1 309  ALA n 
1 310  ASN n 
1 311  ALA n 
1 312  VAL n 
1 313  ALA n 
1 314  ASN n 
1 315  LEU n 
1 316  GLU n 
1 317  LYS n 
1 318  ALA n 
1 319  LEU n 
1 320  ALA n 
1 321  LEU n 
1 322  ASP n 
1 323  PRO n 
1 324  HIS n 
1 325  SER n 
1 326  SER n 
1 327  ASN n 
1 328  ASN n 
1 329  ASP n 
1 330  LYS n 
1 331  TRP n 
1 332  ASN n 
1 333  SER n 
1 334  LEU n 
1 335  LEU n 
1 336  LYS n 
1 337  VAL n 
1 338  ASN n 
1 339  ARG n 
1 340  TYR n 
1 341  TRP n 
1 342  LEU n 
1 343  ALA n 
1 344  ILE n 
1 345  GLN n 
1 346  GLN n 
1 347  GLY n 
1 348  ASP n 
1 349  ALA n 
1 350  ALA n 
1 351  LEU n 
1 352  LYS n 
1 353  ALA n 
1 354  ASN n 
1 355  ASN n 
1 356  PRO n 
1 357  ASP n 
1 358  ARG n 
1 359  ALA n 
1 360  GLU n 
1 361  ARG n 
1 362  LEU n 
1 363  PHE n 
1 364  GLN n 
1 365  GLN n 
1 366  ALA n 
1 367  ARG n 
1 368  ASN n 
1 369  VAL n 
1 370  ASP n 
1 371  ASN n 
1 372  THR n 
1 373  ASP n 
1 374  SER n 
1 375  TYR n 
1 376  ALA n 
1 377  VAL n 
1 378  LEU n 
1 379  GLY n 
1 380  LEU n 
1 381  GLY n 
1 382  ASP n 
1 383  VAL n 
1 384  ALA n 
1 385  MET n 
1 386  ALA n 
1 387  ARG n 
1 388  LYS n 
1 389  ASP n 
1 390  TYR n 
1 391  PRO n 
1 392  ALA n 
1 393  ALA n 
1 394  GLU n 
1 395  ARG n 
1 396  TYR n 
1 397  TYR n 
1 398  GLN n 
1 399  GLN n 
1 400  THR n 
1 401  LEU n 
1 402  ARG n 
1 403  MET n 
1 404  ASP n 
1 405  SER n 
1 406  GLY n 
1 407  ASN n 
1 408  THR n 
1 409  ASN n 
1 410  ALA n 
1 411  VAL n 
1 412  ARG n 
1 413  GLY n 
1 414  LEU n 
1 415  ALA n 
1 416  ASN n 
1 417  ILE n 
1 418  TYR n 
1 419  ARG n 
1 420  GLN n 
1 421  GLN n 
1 422  SER n 
1 423  PRO n 
1 424  GLU n 
1 425  LYS n 
1 426  ALA n 
1 427  GLU n 
1 428  ALA n 
1 429  PHE n 
1 430  ILE n 
1 431  ALA n 
1 432  SER n 
1 433  LEU n 
1 434  SER n 
1 435  ALA n 
1 436  SER n 
1 437  GLN n 
1 438  ARG n 
1 439  ARG n 
1 440  SER n 
1 441  ILE n 
1 442  ASP n 
1 443  ASP n 
1 444  ILE n 
1 445  GLU n 
1 446  ARG n 
1 447  SER n 
1 448  LEU n 
1 449  GLN n 
1 450  ASN n 
1 451  ASP n 
1 452  ARG n 
1 453  LEU n 
1 454  ALA n 
1 455  GLN n 
1 456  GLN n 
1 457  ALA n 
1 458  GLU n 
1 459  ALA n 
1 460  LEU n 
1 461  GLU n 
1 462  ASN n 
1 463  GLN n 
1 464  GLY n 
1 465  LYS n 
1 466  TRP n 
1 467  ALA n 
1 468  GLN n 
1 469  ALA n 
1 470  ALA n 
1 471  ALA n 
1 472  LEU n 
1 473  GLN n 
1 474  ARG n 
1 475  GLN n 
1 476  ARG n 
1 477  LEU n 
1 478  ALA n 
1 479  LEU n 
1 480  ASP n 
1 481  PRO n 
1 482  GLY n 
1 483  SER n 
1 484  VAL n 
1 485  TRP n 
1 486  ILE n 
1 487  THR n 
1 488  TYR n 
1 489  ARG n 
1 490  LEU n 
1 491  SER n 
1 492  GLN n 
1 493  ASP n 
1 494  LEU n 
1 495  TRP n 
1 496  GLN n 
1 497  ALA n 
1 498  GLY n 
1 499  GLN n 
1 500  ARG n 
1 501  SER n 
1 502  GLN n 
1 503  ALA n 
1 504  ASP n 
1 505  THR n 
1 506  LEU n 
1 507  MET n 
1 508  ARG n 
1 509  ASN n 
1 510  LEU n 
1 511  ALA n 
1 512  GLN n 
1 513  GLN n 
1 514  LYS n 
1 515  SER n 
1 516  ASN n 
1 517  ASP n 
1 518  PRO n 
1 519  GLU n 
1 520  GLN n 
1 521  VAL n 
1 522  TYR n 
1 523  ALA n 
1 524  TYR n 
1 525  GLY n 
1 526  LEU n 
1 527  TYR n 
1 528  LEU n 
1 529  SER n 
1 530  GLY n 
1 531  HIS n 
1 532  ASP n 
1 533  GLN n 
1 534  ASP n 
1 535  ARG n 
1 536  ALA n 
1 537  ALA n 
1 538  LEU n 
1 539  ALA n 
1 540  HIS n 
1 541  ILE n 
1 542  ASN n 
1 543  SER n 
1 544  LEU n 
1 545  PRO n 
1 546  ARG n 
1 547  ALA n 
1 548  GLN n 
1 549  TRP n 
1 550  ASN n 
1 551  SER n 
1 552  ASN n 
1 553  ILE n 
1 554  GLN n 
1 555  GLU n 
1 556  LEU n 
1 557  VAL n 
1 558  ASN n 
1 559  ARG n 
1 560  LEU n 
1 561  GLN n 
1 562  SER n 
1 563  ASP n 
1 564  GLN n 
1 565  VAL n 
1 566  LEU n 
1 567  GLU n 
1 568  THR n 
1 569  ALA n 
1 570  ASN n 
1 571  ARG n 
1 572  LEU n 
1 573  ARG n 
1 574  GLU n 
1 575  SER n 
1 576  GLY n 
1 577  LYS n 
1 578  GLU n 
1 579  ALA n 
1 580  GLU n 
1 581  ALA n 
1 582  GLU n 
1 583  ALA n 
1 584  MET n 
1 585  LEU n 
1 586  ARG n 
1 587  GLN n 
1 588  GLN n 
1 589  PRO n 
1 590  PRO n 
1 591  SER n 
1 592  THR n 
1 593  ARG n 
1 594  ILE n 
1 595  ASP n 
1 596  LEU n 
1 597  THR n 
1 598  LEU n 
1 599  ALA n 
1 600  ASP n 
1 601  TRP n 
1 602  ALA n 
1 603  GLN n 
1 604  GLN n 
1 605  ARG n 
1 606  ARG n 
1 607  ASP n 
1 608  TYR n 
1 609  THR n 
1 610  ALA n 
1 611  ALA n 
1 612  ARG n 
1 613  ALA n 
1 614  ALA n 
1 615  TYR n 
1 616  GLN n 
1 617  ASN n 
1 618  VAL n 
1 619  LEU n 
1 620  THR n 
1 621  ARG n 
1 622  GLU n 
1 623  PRO n 
1 624  ALA n 
1 625  ASN n 
1 626  ALA n 
1 627  ASP n 
1 628  ALA n 
1 629  ILE n 
1 630  LEU n 
1 631  GLY n 
1 632  LEU n 
1 633  THR n 
1 634  GLU n 
1 635  VAL n 
1 636  ASP n 
1 637  ILE n 
1 638  ALA n 
1 639  ALA n 
1 640  GLY n 
1 641  ASP n 
1 642  LYS n 
1 643  ALA n 
1 644  ALA n 
1 645  ALA n 
1 646  ARG n 
1 647  SER n 
1 648  GLN n 
1 649  LEU n 
1 650  ALA n 
1 651  LYS n 
1 652  LEU n 
1 653  PRO n 
1 654  ALA n 
1 655  THR n 
1 656  ASP n 
1 657  ASN n 
1 658  ALA n 
1 659  SER n 
1 660  LEU n 
1 661  ASN n 
1 662  THR n 
1 663  GLN n 
1 664  ARG n 
1 665  ARG n 
1 666  VAL n 
1 667  ALA n 
1 668  LEU n 
1 669  ALA n 
1 670  GLN n 
1 671  ALA n 
1 672  GLN n 
1 673  LEU n 
1 674  GLY n 
1 675  ASP n 
1 676  THR n 
1 677  ALA n 
1 678  ALA n 
1 679  ALA n 
1 680  GLN n 
1 681  ARG n 
1 682  THR n 
1 683  PHE n 
1 684  ASN n 
1 685  LYS n 
1 686  LEU n 
1 687  ILE n 
1 688  PRO n 
1 689  GLN n 
1 690  ALA n 
1 691  LYS n 
1 692  SER n 
1 693  GLN n 
1 694  PRO n 
1 695  PRO n 
1 696  SER n 
1 697  MET n 
1 698  GLU n 
1 699  SER n 
1 700  ALA n 
1 701  MET n 
1 702  VAL n 
1 703  LEU n 
1 704  ARG n 
1 705  ASP n 
1 706  GLY n 
1 707  ALA n 
1 708  LYS n 
1 709  PHE n 
1 710  GLU n 
1 711  ALA n 
1 712  GLN n 
1 713  ALA n 
1 714  GLY n 
1 715  ASP n 
1 716  PRO n 
1 717  THR n 
1 718  GLN n 
1 719  ALA n 
1 720  LEU n 
1 721  GLU n 
1 722  THR n 
1 723  TYR n 
1 724  LYS n 
1 725  ASP n 
1 726  ALA n 
1 727  MET n 
1 728  VAL n 
1 729  ALA n 
1 730  SER n 
1 731  GLY n 
1 732  VAL n 
1 733  THR n 
1 734  THR n 
1 735  THR n 
1 736  ARG n 
1 737  PRO n 
1 738  GLN n 
1 739  ASP n 
1 740  ASN n 
1 741  ASP n 
1 742  THR n 
1 743  PHE n 
1 744  THR n 
1 745  ARG n 
1 746  LEU n 
1 747  THR n 
1 748  ARG n 
1 749  ASN n 
1 750  ASP n 
1 751  GLU n 
1 752  LYS n 
1 753  ASP n 
1 754  ASP n 
1 755  TRP n 
1 756  LEU n 
1 757  LYS n 
1 758  ARG n 
1 759  GLY n 
1 760  VAL n 
1 761  ARG n 
1 762  SER n 
1 763  ASP n 
1 764  ALA n 
1 765  ALA n 
1 766  ASP n 
1 767  LEU n 
1 768  TYR n 
1 769  ARG n 
1 770  GLN n 
1 771  GLN n 
1 772  ASP n 
1 773  LEU n 
1 774  ASN n 
1 775  VAL n 
1 776  THR n 
1 777  LEU n 
1 778  GLU n 
1 779  HIS n 
1 780  ASP n 
1 781  TYR n 
1 782  TRP n 
1 783  GLY n 
1 784  SER n 
1 785  SER n 
1 786  GLY n 
1 787  THR n 
1 788  GLY n 
1 789  GLY n 
1 790  TYR n 
1 791  SER n 
1 792  ASP n 
1 793  LEU n 
1 794  LYS n 
1 795  ALA n 
1 796  HIS n 
1 797  THR n 
1 798  THR n 
1 799  MET n 
1 800  LEU n 
1 801  GLN n 
1 802  VAL n 
1 803  ASP n 
1 804  ALA n 
1 805  PRO n 
1 806  TYR n 
1 807  SER n 
1 808  ASP n 
1 809  GLY n 
1 810  ARG n 
1 811  MET n 
1 812  PHE n 
1 813  PHE n 
1 814  ARG n 
1 815  SER n 
1 816  ASP n 
1 817  PHE n 
1 818  VAL n 
1 819  ASN n 
1 820  MET n 
1 821  ASN n 
1 822  VAL n 
1 823  GLY n 
1 824  SER n 
1 825  PHE n 
1 826  SER n 
1 827  THR n 
1 828  ASN n 
1 829  ALA n 
1 830  ASP n 
1 831  GLY n 
1 832  LYS n 
1 833  TRP n 
1 834  ASP n 
1 835  ASP n 
1 836  ASN n 
1 837  TRP n 
1 838  GLY n 
1 839  THR n 
1 840  CYS n 
1 841  THR n 
1 842  LEU n 
1 843  GLN n 
1 844  ASP n 
1 845  CYS n 
1 846  SER n 
1 847  GLY n 
1 848  ASN n 
1 849  ARG n 
1 850  SER n 
1 851  GLN n 
1 852  SER n 
1 853  ASP n 
1 854  SER n 
1 855  GLY n 
1 856  ALA n 
1 857  SER n 
1 858  VAL n 
1 859  ALA n 
1 860  VAL n 
1 861  GLY n 
1 862  TRP n 
1 863  ARG n 
1 864  ASN n 
1 865  ASP n 
1 866  VAL n 
1 867  TRP n 
1 868  SER n 
1 869  TRP n 
1 870  ASP n 
1 871  ILE n 
1 872  GLY n 
1 873  THR n 
1 874  THR n 
1 875  PRO n 
1 876  MET n 
1 877  GLY n 
1 878  PHE n 
1 879  ASN n 
1 880  VAL n 
1 881  VAL n 
1 882  ASP n 
1 883  VAL n 
1 884  VAL n 
1 885  GLY n 
1 886  GLY n 
1 887  ILE n 
1 888  SER n 
1 889  TYR n 
1 890  SER n 
1 891  ASP n 
1 892  ASP n 
1 893  ILE n 
1 894  GLY n 
1 895  PRO n 
1 896  LEU n 
1 897  GLY n 
1 898  TYR n 
1 899  THR n 
1 900  VAL n 
1 901  ASN n 
1 902  ALA n 
1 903  HIS n 
1 904  ARG n 
1 905  ARG n 
1 906  PRO n 
1 907  ILE n 
1 908  SER n 
1 909  SER n 
1 910  SER n 
1 911  LEU n 
1 912  LEU n 
1 913  ALA n 
1 914  PHE n 
1 915  GLY n 
1 916  GLY n 
1 917  GLN n 
1 918  LYS n 
1 919  ASP n 
1 920  SER n 
1 921  PRO n 
1 922  SER n 
1 923  ASN n 
1 924  THR n 
1 925  GLY n 
1 926  LYS n 
1 927  LYS n 
1 928  TRP n 
1 929  GLY n 
1 930  GLY n 
1 931  VAL n 
1 932  ARG n 
1 933  ALA n 
1 934  ASP n 
1 935  GLY n 
1 936  VAL n 
1 937  GLY n 
1 938  LEU n 
1 939  SER n 
1 940  LEU n 
1 941  SER n 
1 942  TYR n 
1 943  ASP n 
1 944  LYS n 
1 945  GLY n 
1 946  GLU n 
1 947  ALA n 
1 948  ASN n 
1 949  GLY n 
1 950  VAL n 
1 951  TRP n 
1 952  ALA n 
1 953  SER n 
1 954  LEU n 
1 955  SER n 
1 956  GLY n 
1 957  ASP n 
1 958  GLN n 
1 959  LEU n 
1 960  THR n 
1 961  GLY n 
1 962  LYS n 
1 963  ASN n 
1 964  VAL n 
1 965  GLU n 
1 966  ASP n 
1 967  ASN n 
1 968  TRP n 
1 969  ARG n 
1 970  VAL n 
1 971  ARG n 
1 972  TRP n 
1 973  MET n 
1 974  THR n 
1 975  GLY n 
1 976  TYR n 
1 977  TYR n 
1 978  TYR n 
1 979  LYS n 
1 980  VAL n 
1 981  ILE n 
1 982  ASN n 
1 983  GLN n 
1 984  ASN n 
1 985  ASN n 
1 986  ARG n 
1 987  ARG n 
1 988  VAL n 
1 989  THR n 
1 990  ILE n 
1 991  GLY n 
1 992  LEU n 
1 993  ASN n 
1 994  ASN n 
1 995  MET n 
1 996  ILE n 
1 997  TRP n 
1 998  HIS n 
1 999  TYR n 
1 1000 ASP n 
1 1001 LYS n 
1 1002 ASP n 
1 1003 LEU n 
1 1004 SER n 
1 1005 GLY n 
1 1006 TYR n 
1 1007 SER n 
1 1008 LEU n 
1 1009 GLY n 
1 1010 GLN n 
1 1011 GLY n 
1 1012 GLY n 
1 1013 TYR n 
1 1014 TYR n 
1 1015 SER n 
1 1016 PRO n 
1 1017 GLN n 
1 1018 GLU n 
1 1019 TYR n 
1 1020 LEU n 
1 1021 SER n 
1 1022 PHE n 
1 1023 ALA n 
1 1024 ILE n 
1 1025 PRO n 
1 1026 VAL n 
1 1027 MET n 
1 1028 TRP n 
1 1029 ARG n 
1 1030 GLU n 
1 1031 ARG n 
1 1032 THR n 
1 1033 GLU n 
1 1034 ASN n 
1 1035 TRP n 
1 1036 SER n 
1 1037 TRP n 
1 1038 GLU n 
1 1039 LEU n 
1 1040 GLY n 
1 1041 ALA n 
1 1042 SER n 
1 1043 GLY n 
1 1044 SER n 
1 1045 TRP n 
1 1046 SER n 
1 1047 HIS n 
1 1048 SER n 
1 1049 ARG n 
1 1050 THR n 
1 1051 LYS n 
1 1052 THR n 
1 1053 MET n 
1 1054 PRO n 
1 1055 ARG n 
1 1056 TYR n 
1 1057 PRO n 
1 1058 LEU n 
1 1059 MET n 
1 1060 ASN n 
1 1061 LEU n 
1 1062 ILE n 
1 1063 PRO n 
1 1064 THR n 
1 1065 ASP n 
1 1066 TRP n 
1 1067 GLN n 
1 1068 GLU n 
1 1069 GLU n 
1 1070 ALA n 
1 1071 ALA n 
1 1072 ARG n 
1 1073 GLN n 
1 1074 SER n 
1 1075 ASN n 
1 1076 ASP n 
1 1077 GLY n 
1 1078 GLY n 
1 1079 SER n 
1 1080 SER n 
1 1081 GLN n 
1 1082 GLY n 
1 1083 PHE n 
1 1084 GLY n 
1 1085 TYR n 
1 1086 THR n 
1 1087 ALA n 
1 1088 ARG n 
1 1089 ALA n 
1 1090 LEU n 
1 1091 LEU n 
1 1092 GLU n 
1 1093 ARG n 
1 1094 ARG n 
1 1095 VAL n 
1 1096 THR n 
1 1097 SER n 
1 1098 ASN n 
1 1099 TRP n 
1 1100 PHE n 
1 1101 VAL n 
1 1102 GLY n 
1 1103 THR n 
1 1104 ALA n 
1 1105 ILE n 
1 1106 ASP n 
1 1107 ILE n 
1 1108 GLN n 
1 1109 GLN n 
1 1110 ALA n 
1 1111 LYS n 
1 1112 ASP n 
1 1113 TYR n 
1 1114 ALA n 
1 1115 PRO n 
1 1116 SER n 
1 1117 HIS n 
1 1118 PHE n 
1 1119 LEU n 
1 1120 LEU n 
1 1121 TYR n 
1 1122 VAL n 
1 1123 ARG n 
1 1124 TYR n 
1 1125 SER n 
1 1126 ALA n 
1 1127 ALA n 
1 1128 GLY n 
1 1129 TRP n 
1 1130 GLN n 
1 1131 GLY n 
1 1132 ASP n 
1 1133 MET n 
1 1134 ASP n 
1 1135 LEU n 
1 1136 PRO n 
1 1137 PRO n 
1 1138 GLN n 
1 1139 PRO n 
1 1140 LEU n 
1 1141 ILE n 
1 1142 PRO n 
1 1143 TYR n 
1 1144 ALA n 
1 1145 ASP n 
1 1146 TRP n 
# 
_entity_src_gen.entity_id                          1 
_entity_src_gen.pdbx_src_id                        1 
_entity_src_gen.pdbx_alt_source_flag               sample 
_entity_src_gen.pdbx_seq_type                      'Biological sequence' 
_entity_src_gen.pdbx_beg_seq_num                   1 
_entity_src_gen.pdbx_end_seq_num                   1146 
_entity_src_gen.gene_src_common_name               ? 
_entity_src_gen.gene_src_genus                     ? 
_entity_src_gen.pdbx_gene_src_gene                 'bcsC, yhjL, b3530, JW5942' 
_entity_src_gen.gene_src_species                   ? 
_entity_src_gen.gene_src_strain                    ? 
_entity_src_gen.gene_src_tissue                    ? 
_entity_src_gen.gene_src_tissue_fraction           ? 
_entity_src_gen.gene_src_details                   ? 
_entity_src_gen.pdbx_gene_src_fragment             ? 
_entity_src_gen.pdbx_gene_src_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_gene_src_ncbi_taxonomy_id     562 
_entity_src_gen.pdbx_gene_src_variant              ? 
_entity_src_gen.pdbx_gene_src_cell_line            ? 
_entity_src_gen.pdbx_gene_src_atcc                 ? 
_entity_src_gen.pdbx_gene_src_organ                ? 
_entity_src_gen.pdbx_gene_src_organelle            ? 
_entity_src_gen.pdbx_gene_src_cell                 ? 
_entity_src_gen.pdbx_gene_src_cellular_location    ? 
_entity_src_gen.host_org_common_name               ? 
_entity_src_gen.pdbx_host_org_scientific_name      'Escherichia coli' 
_entity_src_gen.pdbx_host_org_ncbi_taxonomy_id     562 
_entity_src_gen.host_org_genus                     ? 
_entity_src_gen.pdbx_host_org_gene                 ? 
_entity_src_gen.pdbx_host_org_organ                ? 
_entity_src_gen.host_org_species                   ? 
_entity_src_gen.pdbx_host_org_tissue               ? 
_entity_src_gen.pdbx_host_org_tissue_fraction      ? 
_entity_src_gen.pdbx_host_org_strain               ? 
_entity_src_gen.pdbx_host_org_variant              ? 
_entity_src_gen.pdbx_host_org_cell_line            ? 
_entity_src_gen.pdbx_host_org_atcc                 ? 
_entity_src_gen.pdbx_host_org_culture_collection   ? 
_entity_src_gen.pdbx_host_org_cell                 ? 
_entity_src_gen.pdbx_host_org_organelle            ? 
_entity_src_gen.pdbx_host_org_cellular_location    ? 
_entity_src_gen.pdbx_host_org_vector_type          ? 
_entity_src_gen.pdbx_host_org_vector               ? 
_entity_src_gen.host_org_details                   ? 
_entity_src_gen.expression_system_id               ? 
_entity_src_gen.plasmid_name                       ? 
_entity_src_gen.plasmid_details                    ? 
_entity_src_gen.pdbx_description                   ? 
# 
_pdbx_entity_branch.entity_id   2 
_pdbx_entity_branch.type        oligosaccharide 
# 
loop_
_pdbx_entity_branch_descriptor.ordinal 
_pdbx_entity_branch_descriptor.entity_id 
_pdbx_entity_branch_descriptor.descriptor 
_pdbx_entity_branch_descriptor.type 
_pdbx_entity_branch_descriptor.program 
_pdbx_entity_branch_descriptor.program_version 
1 2 DGlcpb1-4DGlcpb1-4DGlcpb1-4DGlcpb1-ROH                                    'Glycam Condensed Sequence' GMML       1.0   
2 2 'WURCS=2.0/1,4,3/[a2122h-1b_1-5]/1-1-1-1/a4-b1_b4-c1_c4-d1'               WURCS                       PDB2Glycan 1.1.0 
3 2 '[][b-D-Glcp]{[(4+1)][b-D-Glcp]{[(4+1)][b-D-Glcp]{[(4+1)][b-D-Glcp]{}}}}' LINUCS                      PDB-CARE   ?     
# 
loop_
_pdbx_entity_branch_link.link_id 
_pdbx_entity_branch_link.entity_id 
_pdbx_entity_branch_link.entity_branch_list_num_1 
_pdbx_entity_branch_link.comp_id_1 
_pdbx_entity_branch_link.atom_id_1 
_pdbx_entity_branch_link.leaving_atom_id_1 
_pdbx_entity_branch_link.entity_branch_list_num_2 
_pdbx_entity_branch_link.comp_id_2 
_pdbx_entity_branch_link.atom_id_2 
_pdbx_entity_branch_link.leaving_atom_id_2 
_pdbx_entity_branch_link.value_order 
_pdbx_entity_branch_link.details 
1 2 2 BGC C1 O1 1 BGC O4 HO4 sing ? 
2 2 3 BGC C1 O1 2 BGC O4 HO4 sing ? 
3 2 4 BGC C1 O1 3 BGC O4 HO4 sing ? 
# 
loop_
_chem_comp.id 
_chem_comp.type 
_chem_comp.mon_nstd_flag 
_chem_comp.name 
_chem_comp.pdbx_synonyms 
_chem_comp.formula 
_chem_comp.formula_weight 
ALA 'L-peptide linking'          y ALANINE              ?                                    'C3 H7 N O2'     89.093  
ARG 'L-peptide linking'          y ARGININE             ?                                    'C6 H15 N4 O2 1' 175.209 
ASN 'L-peptide linking'          y ASPARAGINE           ?                                    'C4 H8 N2 O3'    132.118 
ASP 'L-peptide linking'          y 'ASPARTIC ACID'      ?                                    'C4 H7 N O4'     133.103 
BGC 'D-saccharide, beta linking' . beta-D-glucopyranose 'beta-D-glucose; D-glucose; glucose' 'C6 H12 O6'      180.156 
CYS 'L-peptide linking'          y CYSTEINE             ?                                    'C3 H7 N O2 S'   121.158 
GLN 'L-peptide linking'          y GLUTAMINE            ?                                    'C5 H10 N2 O3'   146.144 
GLU 'L-peptide linking'          y 'GLUTAMIC ACID'      ?                                    'C5 H9 N O4'     147.129 
GLY 'peptide linking'            y GLYCINE              ?                                    'C2 H5 N O2'     75.067  
HIS 'L-peptide linking'          y HISTIDINE            ?                                    'C6 H10 N3 O2 1' 156.162 
ILE 'L-peptide linking'          y ISOLEUCINE           ?                                    'C6 H13 N O2'    131.173 
LEU 'L-peptide linking'          y LEUCINE              ?                                    'C6 H13 N O2'    131.173 
LYS 'L-peptide linking'          y LYSINE               ?                                    'C6 H15 N2 O2 1' 147.195 
MET 'L-peptide linking'          y METHIONINE           ?                                    'C5 H11 N O2 S'  149.211 
PHE 'L-peptide linking'          y PHENYLALANINE        ?                                    'C9 H11 N O2'    165.189 
PRO 'L-peptide linking'          y PROLINE              ?                                    'C5 H9 N O2'     115.130 
SER 'L-peptide linking'          y SERINE               ?                                    'C3 H7 N O3'     105.093 
THR 'L-peptide linking'          y THREONINE            ?                                    'C4 H9 N O3'     119.119 
TRP 'L-peptide linking'          y TRYPTOPHAN           ?                                    'C11 H12 N2 O2'  204.225 
TYR 'L-peptide linking'          y TYROSINE             ?                                    'C9 H11 N O3'    181.189 
VAL 'L-peptide linking'          y VALINE               ?                                    'C5 H11 N O2'    117.146 
# 
loop_
_pdbx_chem_comp_identifier.comp_id 
_pdbx_chem_comp_identifier.type 
_pdbx_chem_comp_identifier.program 
_pdbx_chem_comp_identifier.program_version 
_pdbx_chem_comp_identifier.identifier 
BGC 'CONDENSED IUPAC CARBOHYDRATE SYMBOL' GMML     1.0 DGlcpb            
BGC 'COMMON NAME'                         GMML     1.0 b-D-glucopyranose 
BGC 'IUPAC CARBOHYDRATE SYMBOL'           PDB-CARE 1.0 b-D-Glcp          
BGC 'SNFG CARBOHYDRATE SYMBOL'            GMML     1.0 Glc               
# 
loop_
_pdbx_poly_seq_scheme.asym_id 
_pdbx_poly_seq_scheme.entity_id 
_pdbx_poly_seq_scheme.seq_id 
_pdbx_poly_seq_scheme.mon_id 
_pdbx_poly_seq_scheme.ndb_seq_num 
_pdbx_poly_seq_scheme.pdb_seq_num 
_pdbx_poly_seq_scheme.auth_seq_num 
_pdbx_poly_seq_scheme.pdb_mon_id 
_pdbx_poly_seq_scheme.auth_mon_id 
_pdbx_poly_seq_scheme.pdb_strand_id 
_pdbx_poly_seq_scheme.pdb_ins_code 
_pdbx_poly_seq_scheme.hetero 
A 1 1    MET 1    12   ?    ?   ?   A . n 
A 1 2    HIS 2    13   ?    ?   ?   A . n 
A 1 3    HIS 3    14   ?    ?   ?   A . n 
A 1 4    HIS 4    15   ?    ?   ?   A . n 
A 1 5    HIS 5    16   ?    ?   ?   A . n 
A 1 6    HIS 6    17   ?    ?   ?   A . n 
A 1 7    HIS 7    18   ?    ?   ?   A . n 
A 1 8    HIS 8    19   ?    ?   ?   A . n 
A 1 9    HIS 9    20   ?    ?   ?   A . n 
A 1 10   VAL 10   21   ?    ?   ?   A . n 
A 1 11   GLU 11   22   ?    ?   ?   A . n 
A 1 12   ALA 12   23   ?    ?   ?   A . n 
A 1 13   ALA 13   24   ?    ?   ?   A . n 
A 1 14   PRO 14   25   ?    ?   ?   A . n 
A 1 15   THR 15   26   ?    ?   ?   A . n 
A 1 16   ALA 16   27   ?    ?   ?   A . n 
A 1 17   GLN 17   28   ?    ?   ?   A . n 
A 1 18   GLN 18   29   ?    ?   ?   A . n 
A 1 19   GLN 19   30   ?    ?   ?   A . n 
A 1 20   LEU 20   31   ?    ?   ?   A . n 
A 1 21   LEU 21   32   ?    ?   ?   A . n 
A 1 22   GLU 22   33   ?    ?   ?   A . n 
A 1 23   GLN 23   34   ?    ?   ?   A . n 
A 1 24   VAL 24   35   ?    ?   ?   A . n 
A 1 25   ARG 25   36   ?    ?   ?   A . n 
A 1 26   LEU 26   37   ?    ?   ?   A . n 
A 1 27   GLY 27   38   ?    ?   ?   A . n 
A 1 28   GLU 28   39   ?    ?   ?   A . n 
A 1 29   ALA 29   40   ?    ?   ?   A . n 
A 1 30   THR 30   41   ?    ?   ?   A . n 
A 1 31   HIS 31   42   ?    ?   ?   A . n 
A 1 32   ARG 32   43   ?    ?   ?   A . n 
A 1 33   GLU 33   44   ?    ?   ?   A . n 
A 1 34   ASP 34   45   ?    ?   ?   A . n 
A 1 35   LEU 35   46   ?    ?   ?   A . n 
A 1 36   VAL 36   47   ?    ?   ?   A . n 
A 1 37   GLN 37   48   ?    ?   ?   A . n 
A 1 38   GLN 38   49   ?    ?   ?   A . n 
A 1 39   SER 39   50   ?    ?   ?   A . n 
A 1 40   LEU 40   51   ?    ?   ?   A . n 
A 1 41   TYR 41   52   ?    ?   ?   A . n 
A 1 42   ARG 42   53   ?    ?   ?   A . n 
A 1 43   LEU 43   54   ?    ?   ?   A . n 
A 1 44   GLU 44   55   ?    ?   ?   A . n 
A 1 45   LEU 45   56   ?    ?   ?   A . n 
A 1 46   ILE 46   57   ?    ?   ?   A . n 
A 1 47   ASP 47   58   ?    ?   ?   A . n 
A 1 48   PRO 48   59   ?    ?   ?   A . n 
A 1 49   ASN 49   60   ?    ?   ?   A . n 
A 1 50   ASN 50   61   ?    ?   ?   A . n 
A 1 51   PRO 51   62   ?    ?   ?   A . n 
A 1 52   ASP 52   63   ?    ?   ?   A . n 
A 1 53   VAL 53   64   ?    ?   ?   A . n 
A 1 54   VAL 54   65   ?    ?   ?   A . n 
A 1 55   ALA 55   66   ?    ?   ?   A . n 
A 1 56   ALA 56   67   ?    ?   ?   A . n 
A 1 57   ARG 57   68   ?    ?   ?   A . n 
A 1 58   PHE 58   69   ?    ?   ?   A . n 
A 1 59   ARG 59   70   ?    ?   ?   A . n 
A 1 60   SER 60   71   ?    ?   ?   A . n 
A 1 61   LEU 61   72   ?    ?   ?   A . n 
A 1 62   LEU 62   73   ?    ?   ?   A . n 
A 1 63   ARG 63   74   ?    ?   ?   A . n 
A 1 64   GLN 64   75   ?    ?   ?   A . n 
A 1 65   GLY 65   76   ?    ?   ?   A . n 
A 1 66   ASP 66   77   ?    ?   ?   A . n 
A 1 67   ILE 67   78   ?    ?   ?   A . n 
A 1 68   ASP 68   79   ?    ?   ?   A . n 
A 1 69   GLY 69   80   ?    ?   ?   A . n 
A 1 70   ALA 70   81   ?    ?   ?   A . n 
A 1 71   GLN 71   82   ?    ?   ?   A . n 
A 1 72   LYS 72   83   ?    ?   ?   A . n 
A 1 73   GLN 73   84   ?    ?   ?   A . n 
A 1 74   LEU 74   85   ?    ?   ?   A . n 
A 1 75   ASP 75   86   ?    ?   ?   A . n 
A 1 76   ARG 76   87   ?    ?   ?   A . n 
A 1 77   LEU 77   88   ?    ?   ?   A . n 
A 1 78   SER 78   89   ?    ?   ?   A . n 
A 1 79   GLN 79   90   ?    ?   ?   A . n 
A 1 80   LEU 80   91   ?    ?   ?   A . n 
A 1 81   ALA 81   92   ?    ?   ?   A . n 
A 1 82   PRO 82   93   ?    ?   ?   A . n 
A 1 83   SER 83   94   ?    ?   ?   A . n 
A 1 84   SER 84   95   ?    ?   ?   A . n 
A 1 85   ASN 85   96   ?    ?   ?   A . n 
A 1 86   ALA 86   97   ?    ?   ?   A . n 
A 1 87   TYR 87   98   ?    ?   ?   A . n 
A 1 88   LYS 88   99   ?    ?   ?   A . n 
A 1 89   SER 89   100  ?    ?   ?   A . n 
A 1 90   SER 90   101  ?    ?   ?   A . n 
A 1 91   ARG 91   102  ?    ?   ?   A . n 
A 1 92   THR 92   103  ?    ?   ?   A . n 
A 1 93   THR 93   104  ?    ?   ?   A . n 
A 1 94   MET 94   105  ?    ?   ?   A . n 
A 1 95   LEU 95   106  ?    ?   ?   A . n 
A 1 96   LEU 96   107  ?    ?   ?   A . n 
A 1 97   SER 97   108  ?    ?   ?   A . n 
A 1 98   THR 98   109  ?    ?   ?   A . n 
A 1 99   PRO 99   110  ?    ?   ?   A . n 
A 1 100  ASP 100  111  ?    ?   ?   A . n 
A 1 101  GLY 101  112  ?    ?   ?   A . n 
A 1 102  ARG 102  113  ?    ?   ?   A . n 
A 1 103  GLN 103  114  ?    ?   ?   A . n 
A 1 104  ALA 104  115  ?    ?   ?   A . n 
A 1 105  LEU 105  116  ?    ?   ?   A . n 
A 1 106  GLN 106  117  ?    ?   ?   A . n 
A 1 107  GLN 107  118  ?    ?   ?   A . n 
A 1 108  ALA 108  119  ?    ?   ?   A . n 
A 1 109  ARG 109  120  ?    ?   ?   A . n 
A 1 110  LEU 110  121  ?    ?   ?   A . n 
A 1 111  GLN 111  122  ?    ?   ?   A . n 
A 1 112  ALA 112  123  ?    ?   ?   A . n 
A 1 113  THR 113  124  ?    ?   ?   A . n 
A 1 114  THR 114  125  ?    ?   ?   A . n 
A 1 115  GLY 115  126  ?    ?   ?   A . n 
A 1 116  HIS 116  127  ?    ?   ?   A . n 
A 1 117  ALA 117  128  ?    ?   ?   A . n 
A 1 118  GLU 118  129  ?    ?   ?   A . n 
A 1 119  GLU 119  130  ?    ?   ?   A . n 
A 1 120  ALA 120  131  ?    ?   ?   A . n 
A 1 121  VAL 121  132  ?    ?   ?   A . n 
A 1 122  ALA 122  133  ?    ?   ?   A . n 
A 1 123  SER 123  134  ?    ?   ?   A . n 
A 1 124  TYR 124  135  ?    ?   ?   A . n 
A 1 125  ASN 125  136  ?    ?   ?   A . n 
A 1 126  LYS 126  137  ?    ?   ?   A . n 
A 1 127  LEU 127  138  ?    ?   ?   A . n 
A 1 128  PHE 128  139  ?    ?   ?   A . n 
A 1 129  ASN 129  140  ?    ?   ?   A . n 
A 1 130  GLY 130  141  ?    ?   ?   A . n 
A 1 131  ALA 131  142  ?    ?   ?   A . n 
A 1 132  PRO 132  143  ?    ?   ?   A . n 
A 1 133  PRO 133  144  ?    ?   ?   A . n 
A 1 134  GLU 134  145  ?    ?   ?   A . n 
A 1 135  GLY 135  146  ?    ?   ?   A . n 
A 1 136  ASP 136  147  ?    ?   ?   A . n 
A 1 137  ILE 137  148  ?    ?   ?   A . n 
A 1 138  ALA 138  149  ?    ?   ?   A . n 
A 1 139  VAL 139  150  ?    ?   ?   A . n 
A 1 140  GLU 140  151  ?    ?   ?   A . n 
A 1 141  TYR 141  152  ?    ?   ?   A . n 
A 1 142  TRP 142  153  ?    ?   ?   A . n 
A 1 143  SER 143  154  ?    ?   ?   A . n 
A 1 144  THR 144  155  ?    ?   ?   A . n 
A 1 145  VAL 145  156  ?    ?   ?   A . n 
A 1 146  ALA 146  157  ?    ?   ?   A . n 
A 1 147  LYS 147  158  ?    ?   ?   A . n 
A 1 148  ILE 148  159  ?    ?   ?   A . n 
A 1 149  PRO 149  160  ?    ?   ?   A . n 
A 1 150  ALA 150  161  ?    ?   ?   A . n 
A 1 151  ARG 151  162  ?    ?   ?   A . n 
A 1 152  ARG 152  163  ?    ?   ?   A . n 
A 1 153  GLY 153  164  ?    ?   ?   A . n 
A 1 154  GLU 154  165  ?    ?   ?   A . n 
A 1 155  ALA 155  166  ?    ?   ?   A . n 
A 1 156  ILE 156  167  ?    ?   ?   A . n 
A 1 157  ASN 157  168  ?    ?   ?   A . n 
A 1 158  GLN 158  169  ?    ?   ?   A . n 
A 1 159  LEU 159  170  ?    ?   ?   A . n 
A 1 160  LYS 160  171  ?    ?   ?   A . n 
A 1 161  ARG 161  172  ?    ?   ?   A . n 
A 1 162  ILE 162  173  ?    ?   ?   A . n 
A 1 163  ASN 163  174  ?    ?   ?   A . n 
A 1 164  ALA 164  175  ?    ?   ?   A . n 
A 1 165  ASP 165  176  ?    ?   ?   A . n 
A 1 166  ALA 166  177  ?    ?   ?   A . n 
A 1 167  PRO 167  178  ?    ?   ?   A . n 
A 1 168  GLY 168  179  ?    ?   ?   A . n 
A 1 169  ASN 169  180  ?    ?   ?   A . n 
A 1 170  THR 170  181  ?    ?   ?   A . n 
A 1 171  GLY 171  182  ?    ?   ?   A . n 
A 1 172  LEU 172  183  ?    ?   ?   A . n 
A 1 173  GLN 173  184  ?    ?   ?   A . n 
A 1 174  ASN 174  185  ?    ?   ?   A . n 
A 1 175  ASN 175  186  ?    ?   ?   A . n 
A 1 176  LEU 176  187  ?    ?   ?   A . n 
A 1 177  ALA 177  188  ?    ?   ?   A . n 
A 1 178  LEU 178  189  ?    ?   ?   A . n 
A 1 179  LEU 179  190  ?    ?   ?   A . n 
A 1 180  LEU 180  191  ?    ?   ?   A . n 
A 1 181  PHE 181  192  ?    ?   ?   A . n 
A 1 182  SER 182  193  ?    ?   ?   A . n 
A 1 183  SER 183  194  ?    ?   ?   A . n 
A 1 184  ASP 184  195  ?    ?   ?   A . n 
A 1 185  ARG 185  196  ?    ?   ?   A . n 
A 1 186  ARG 186  197  ?    ?   ?   A . n 
A 1 187  ASP 187  198  ?    ?   ?   A . n 
A 1 188  GLU 188  199  ?    ?   ?   A . n 
A 1 189  GLY 189  200  ?    ?   ?   A . n 
A 1 190  PHE 190  201  ?    ?   ?   A . n 
A 1 191  ALA 191  202  ?    ?   ?   A . n 
A 1 192  VAL 192  203  ?    ?   ?   A . n 
A 1 193  LEU 193  204  ?    ?   ?   A . n 
A 1 194  GLU 194  205  ?    ?   ?   A . n 
A 1 195  GLN 195  206  ?    ?   ?   A . n 
A 1 196  MET 196  207  ?    ?   ?   A . n 
A 1 197  ALA 197  208  ?    ?   ?   A . n 
A 1 198  LYS 198  209  ?    ?   ?   A . n 
A 1 199  SER 199  210  ?    ?   ?   A . n 
A 1 200  ASN 200  211  ?    ?   ?   A . n 
A 1 201  ALA 201  212  ?    ?   ?   A . n 
A 1 202  GLY 202  213  ?    ?   ?   A . n 
A 1 203  ARG 203  214  ?    ?   ?   A . n 
A 1 204  GLU 204  215  ?    ?   ?   A . n 
A 1 205  GLY 205  216  ?    ?   ?   A . n 
A 1 206  ALA 206  217  ?    ?   ?   A . n 
A 1 207  SER 207  218  ?    ?   ?   A . n 
A 1 208  LYS 208  219  ?    ?   ?   A . n 
A 1 209  ILE 209  220  ?    ?   ?   A . n 
A 1 210  TRP 210  221  ?    ?   ?   A . n 
A 1 211  TYR 211  222  ?    ?   ?   A . n 
A 1 212  GLY 212  223  ?    ?   ?   A . n 
A 1 213  GLN 213  224  ?    ?   ?   A . n 
A 1 214  ILE 214  225  ?    ?   ?   A . n 
A 1 215  LYS 215  226  ?    ?   ?   A . n 
A 1 216  ASP 216  227  ?    ?   ?   A . n 
A 1 217  MET 217  228  ?    ?   ?   A . n 
A 1 218  PRO 218  229  ?    ?   ?   A . n 
A 1 219  VAL 219  230  ?    ?   ?   A . n 
A 1 220  SER 220  231  ?    ?   ?   A . n 
A 1 221  ASP 221  232  ?    ?   ?   A . n 
A 1 222  ALA 222  233  ?    ?   ?   A . n 
A 1 223  SER 223  234  ?    ?   ?   A . n 
A 1 224  VAL 224  235  ?    ?   ?   A . n 
A 1 225  SER 225  236  ?    ?   ?   A . n 
A 1 226  ALA 226  237  ?    ?   ?   A . n 
A 1 227  LEU 227  238  ?    ?   ?   A . n 
A 1 228  LYS 228  239  ?    ?   ?   A . n 
A 1 229  LYS 229  240  ?    ?   ?   A . n 
A 1 230  TYR 230  241  ?    ?   ?   A . n 
A 1 231  LEU 231  242  ?    ?   ?   A . n 
A 1 232  SER 232  243  ?    ?   ?   A . n 
A 1 233  ILE 233  244  ?    ?   ?   A . n 
A 1 234  PHE 234  245  ?    ?   ?   A . n 
A 1 235  SER 235  246  ?    ?   ?   A . n 
A 1 236  ASP 236  247  ?    ?   ?   A . n 
A 1 237  GLY 237  248  ?    ?   ?   A . n 
A 1 238  ASP 238  249  ?    ?   ?   A . n 
A 1 239  SER 239  250  ?    ?   ?   A . n 
A 1 240  VAL 240  251  ?    ?   ?   A . n 
A 1 241  ALA 241  252  ?    ?   ?   A . n 
A 1 242  ALA 242  253  ?    ?   ?   A . n 
A 1 243  ALA 243  254  ?    ?   ?   A . n 
A 1 244  GLN 244  255  ?    ?   ?   A . n 
A 1 245  SER 245  256  ?    ?   ?   A . n 
A 1 246  GLN 246  257  ?    ?   ?   A . n 
A 1 247  LEU 247  258  ?    ?   ?   A . n 
A 1 248  ALA 248  259  ?    ?   ?   A . n 
A 1 249  GLU 249  260  ?    ?   ?   A . n 
A 1 250  GLN 250  261  ?    ?   ?   A . n 
A 1 251  GLN 251  262  ?    ?   ?   A . n 
A 1 252  LYS 252  263  ?    ?   ?   A . n 
A 1 253  GLN 253  264  ?    ?   ?   A . n 
A 1 254  LEU 254  265  ?    ?   ?   A . n 
A 1 255  ALA 255  266  ?    ?   ?   A . n 
A 1 256  ASP 256  267  ?    ?   ?   A . n 
A 1 257  PRO 257  268  ?    ?   ?   A . n 
A 1 258  ALA 258  269  ?    ?   ?   A . n 
A 1 259  PHE 259  270  ?    ?   ?   A . n 
A 1 260  ARG 260  271  ?    ?   ?   A . n 
A 1 261  ALA 261  272  ?    ?   ?   A . n 
A 1 262  ARG 262  273  ?    ?   ?   A . n 
A 1 263  ALA 263  274  ?    ?   ?   A . n 
A 1 264  GLN 264  275  ?    ?   ?   A . n 
A 1 265  GLY 265  276  ?    ?   ?   A . n 
A 1 266  LEU 266  277  ?    ?   ?   A . n 
A 1 267  ALA 267  278  ?    ?   ?   A . n 
A 1 268  ALA 268  279  ?    ?   ?   A . n 
A 1 269  VAL 269  280  ?    ?   ?   A . n 
A 1 270  ASP 270  281  ?    ?   ?   A . n 
A 1 271  SER 271  282  ?    ?   ?   A . n 
A 1 272  GLY 272  283  ?    ?   ?   A . n 
A 1 273  MET 273  284  ?    ?   ?   A . n 
A 1 274  ALA 274  285  ?    ?   ?   A . n 
A 1 275  GLY 275  286  ?    ?   ?   A . n 
A 1 276  LYS 276  287  ?    ?   ?   A . n 
A 1 277  ALA 277  288  ?    ?   ?   A . n 
A 1 278  ILE 278  289  ?    ?   ?   A . n 
A 1 279  PRO 279  290  ?    ?   ?   A . n 
A 1 280  GLU 280  291  ?    ?   ?   A . n 
A 1 281  LEU 281  292  ?    ?   ?   A . n 
A 1 282  GLN 282  293  ?    ?   ?   A . n 
A 1 283  GLN 283  294  ?    ?   ?   A . n 
A 1 284  ALA 284  295  ?    ?   ?   A . n 
A 1 285  VAL 285  296  ?    ?   ?   A . n 
A 1 286  ARG 286  297  ?    ?   ?   A . n 
A 1 287  ALA 287  298  ?    ?   ?   A . n 
A 1 288  ASN 288  299  ?    ?   ?   A . n 
A 1 289  PRO 289  300  ?    ?   ?   A . n 
A 1 290  LYS 290  301  ?    ?   ?   A . n 
A 1 291  ASP 291  302  ?    ?   ?   A . n 
A 1 292  SER 292  303  ?    ?   ?   A . n 
A 1 293  GLU 293  304  ?    ?   ?   A . n 
A 1 294  ALA 294  305  ?    ?   ?   A . n 
A 1 295  LEU 295  306  ?    ?   ?   A . n 
A 1 296  GLY 296  307  ?    ?   ?   A . n 
A 1 297  ALA 297  308  ?    ?   ?   A . n 
A 1 298  LEU 298  309  ?    ?   ?   A . n 
A 1 299  GLY 299  310  ?    ?   ?   A . n 
A 1 300  GLN 300  311  ?    ?   ?   A . n 
A 1 301  ALA 301  312  ?    ?   ?   A . n 
A 1 302  TYR 302  313  ?    ?   ?   A . n 
A 1 303  SER 303  314  ?    ?   ?   A . n 
A 1 304  GLN 304  315  ?    ?   ?   A . n 
A 1 305  LYS 305  316  ?    ?   ?   A . n 
A 1 306  GLY 306  317  ?    ?   ?   A . n 
A 1 307  ASP 307  318  ?    ?   ?   A . n 
A 1 308  ARG 308  319  ?    ?   ?   A . n 
A 1 309  ALA 309  320  ?    ?   ?   A . n 
A 1 310  ASN 310  321  ?    ?   ?   A . n 
A 1 311  ALA 311  322  ?    ?   ?   A . n 
A 1 312  VAL 312  323  ?    ?   ?   A . n 
A 1 313  ALA 313  324  ?    ?   ?   A . n 
A 1 314  ASN 314  325  ?    ?   ?   A . n 
A 1 315  LEU 315  326  ?    ?   ?   A . n 
A 1 316  GLU 316  327  ?    ?   ?   A . n 
A 1 317  LYS 317  328  ?    ?   ?   A . n 
A 1 318  ALA 318  329  ?    ?   ?   A . n 
A 1 319  LEU 319  330  ?    ?   ?   A . n 
A 1 320  ALA 320  331  ?    ?   ?   A . n 
A 1 321  LEU 321  332  ?    ?   ?   A . n 
A 1 322  ASP 322  333  ?    ?   ?   A . n 
A 1 323  PRO 323  334  ?    ?   ?   A . n 
A 1 324  HIS 324  335  ?    ?   ?   A . n 
A 1 325  SER 325  336  ?    ?   ?   A . n 
A 1 326  SER 326  337  ?    ?   ?   A . n 
A 1 327  ASN 327  338  ?    ?   ?   A . n 
A 1 328  ASN 328  339  ?    ?   ?   A . n 
A 1 329  ASP 329  340  ?    ?   ?   A . n 
A 1 330  LYS 330  341  ?    ?   ?   A . n 
A 1 331  TRP 331  342  ?    ?   ?   A . n 
A 1 332  ASN 332  343  ?    ?   ?   A . n 
A 1 333  SER 333  344  ?    ?   ?   A . n 
A 1 334  LEU 334  345  ?    ?   ?   A . n 
A 1 335  LEU 335  346  ?    ?   ?   A . n 
A 1 336  LYS 336  347  ?    ?   ?   A . n 
A 1 337  VAL 337  348  ?    ?   ?   A . n 
A 1 338  ASN 338  349  ?    ?   ?   A . n 
A 1 339  ARG 339  350  ?    ?   ?   A . n 
A 1 340  TYR 340  351  ?    ?   ?   A . n 
A 1 341  TRP 341  352  ?    ?   ?   A . n 
A 1 342  LEU 342  353  ?    ?   ?   A . n 
A 1 343  ALA 343  354  ?    ?   ?   A . n 
A 1 344  ILE 344  355  ?    ?   ?   A . n 
A 1 345  GLN 345  356  ?    ?   ?   A . n 
A 1 346  GLN 346  357  ?    ?   ?   A . n 
A 1 347  GLY 347  358  ?    ?   ?   A . n 
A 1 348  ASP 348  359  ?    ?   ?   A . n 
A 1 349  ALA 349  360  ?    ?   ?   A . n 
A 1 350  ALA 350  361  ?    ?   ?   A . n 
A 1 351  LEU 351  362  ?    ?   ?   A . n 
A 1 352  LYS 352  363  ?    ?   ?   A . n 
A 1 353  ALA 353  364  ?    ?   ?   A . n 
A 1 354  ASN 354  365  ?    ?   ?   A . n 
A 1 355  ASN 355  366  ?    ?   ?   A . n 
A 1 356  PRO 356  367  ?    ?   ?   A . n 
A 1 357  ASP 357  368  ?    ?   ?   A . n 
A 1 358  ARG 358  369  ?    ?   ?   A . n 
A 1 359  ALA 359  370  ?    ?   ?   A . n 
A 1 360  GLU 360  371  ?    ?   ?   A . n 
A 1 361  ARG 361  372  ?    ?   ?   A . n 
A 1 362  LEU 362  373  ?    ?   ?   A . n 
A 1 363  PHE 363  374  ?    ?   ?   A . n 
A 1 364  GLN 364  375  ?    ?   ?   A . n 
A 1 365  GLN 365  376  ?    ?   ?   A . n 
A 1 366  ALA 366  377  ?    ?   ?   A . n 
A 1 367  ARG 367  378  ?    ?   ?   A . n 
A 1 368  ASN 368  379  ?    ?   ?   A . n 
A 1 369  VAL 369  380  ?    ?   ?   A . n 
A 1 370  ASP 370  381  ?    ?   ?   A . n 
A 1 371  ASN 371  382  ?    ?   ?   A . n 
A 1 372  THR 372  383  ?    ?   ?   A . n 
A 1 373  ASP 373  384  ?    ?   ?   A . n 
A 1 374  SER 374  385  ?    ?   ?   A . n 
A 1 375  TYR 375  386  ?    ?   ?   A . n 
A 1 376  ALA 376  387  ?    ?   ?   A . n 
A 1 377  VAL 377  388  ?    ?   ?   A . n 
A 1 378  LEU 378  389  ?    ?   ?   A . n 
A 1 379  GLY 379  390  ?    ?   ?   A . n 
A 1 380  LEU 380  391  ?    ?   ?   A . n 
A 1 381  GLY 381  392  ?    ?   ?   A . n 
A 1 382  ASP 382  393  ?    ?   ?   A . n 
A 1 383  VAL 383  394  ?    ?   ?   A . n 
A 1 384  ALA 384  395  ?    ?   ?   A . n 
A 1 385  MET 385  396  ?    ?   ?   A . n 
A 1 386  ALA 386  397  ?    ?   ?   A . n 
A 1 387  ARG 387  398  ?    ?   ?   A . n 
A 1 388  LYS 388  399  ?    ?   ?   A . n 
A 1 389  ASP 389  400  ?    ?   ?   A . n 
A 1 390  TYR 390  401  ?    ?   ?   A . n 
A 1 391  PRO 391  402  ?    ?   ?   A . n 
A 1 392  ALA 392  403  ?    ?   ?   A . n 
A 1 393  ALA 393  404  ?    ?   ?   A . n 
A 1 394  GLU 394  405  ?    ?   ?   A . n 
A 1 395  ARG 395  406  ?    ?   ?   A . n 
A 1 396  TYR 396  407  ?    ?   ?   A . n 
A 1 397  TYR 397  408  ?    ?   ?   A . n 
A 1 398  GLN 398  409  ?    ?   ?   A . n 
A 1 399  GLN 399  410  ?    ?   ?   A . n 
A 1 400  THR 400  411  ?    ?   ?   A . n 
A 1 401  LEU 401  412  ?    ?   ?   A . n 
A 1 402  ARG 402  413  ?    ?   ?   A . n 
A 1 403  MET 403  414  ?    ?   ?   A . n 
A 1 404  ASP 404  415  ?    ?   ?   A . n 
A 1 405  SER 405  416  ?    ?   ?   A . n 
A 1 406  GLY 406  417  ?    ?   ?   A . n 
A 1 407  ASN 407  418  ?    ?   ?   A . n 
A 1 408  THR 408  419  ?    ?   ?   A . n 
A 1 409  ASN 409  420  ?    ?   ?   A . n 
A 1 410  ALA 410  421  ?    ?   ?   A . n 
A 1 411  VAL 411  422  ?    ?   ?   A . n 
A 1 412  ARG 412  423  ?    ?   ?   A . n 
A 1 413  GLY 413  424  ?    ?   ?   A . n 
A 1 414  LEU 414  425  ?    ?   ?   A . n 
A 1 415  ALA 415  426  ?    ?   ?   A . n 
A 1 416  ASN 416  427  ?    ?   ?   A . n 
A 1 417  ILE 417  428  ?    ?   ?   A . n 
A 1 418  TYR 418  429  ?    ?   ?   A . n 
A 1 419  ARG 419  430  ?    ?   ?   A . n 
A 1 420  GLN 420  431  ?    ?   ?   A . n 
A 1 421  GLN 421  432  ?    ?   ?   A . n 
A 1 422  SER 422  433  ?    ?   ?   A . n 
A 1 423  PRO 423  434  ?    ?   ?   A . n 
A 1 424  GLU 424  435  ?    ?   ?   A . n 
A 1 425  LYS 425  436  ?    ?   ?   A . n 
A 1 426  ALA 426  437  ?    ?   ?   A . n 
A 1 427  GLU 427  438  ?    ?   ?   A . n 
A 1 428  ALA 428  439  ?    ?   ?   A . n 
A 1 429  PHE 429  440  ?    ?   ?   A . n 
A 1 430  ILE 430  441  ?    ?   ?   A . n 
A 1 431  ALA 431  442  ?    ?   ?   A . n 
A 1 432  SER 432  443  ?    ?   ?   A . n 
A 1 433  LEU 433  444  ?    ?   ?   A . n 
A 1 434  SER 434  445  ?    ?   ?   A . n 
A 1 435  ALA 435  446  ?    ?   ?   A . n 
A 1 436  SER 436  447  ?    ?   ?   A . n 
A 1 437  GLN 437  448  ?    ?   ?   A . n 
A 1 438  ARG 438  449  ?    ?   ?   A . n 
A 1 439  ARG 439  450  ?    ?   ?   A . n 
A 1 440  SER 440  451  ?    ?   ?   A . n 
A 1 441  ILE 441  452  ?    ?   ?   A . n 
A 1 442  ASP 442  453  ?    ?   ?   A . n 
A 1 443  ASP 443  454  ?    ?   ?   A . n 
A 1 444  ILE 444  455  ?    ?   ?   A . n 
A 1 445  GLU 445  456  ?    ?   ?   A . n 
A 1 446  ARG 446  457  ?    ?   ?   A . n 
A 1 447  SER 447  458  ?    ?   ?   A . n 
A 1 448  LEU 448  459  ?    ?   ?   A . n 
A 1 449  GLN 449  460  ?    ?   ?   A . n 
A 1 450  ASN 450  461  ?    ?   ?   A . n 
A 1 451  ASP 451  462  ?    ?   ?   A . n 
A 1 452  ARG 452  463  ?    ?   ?   A . n 
A 1 453  LEU 453  464  ?    ?   ?   A . n 
A 1 454  ALA 454  465  ?    ?   ?   A . n 
A 1 455  GLN 455  466  ?    ?   ?   A . n 
A 1 456  GLN 456  467  ?    ?   ?   A . n 
A 1 457  ALA 457  468  ?    ?   ?   A . n 
A 1 458  GLU 458  469  ?    ?   ?   A . n 
A 1 459  ALA 459  470  ?    ?   ?   A . n 
A 1 460  LEU 460  471  ?    ?   ?   A . n 
A 1 461  GLU 461  472  ?    ?   ?   A . n 
A 1 462  ASN 462  473  ?    ?   ?   A . n 
A 1 463  GLN 463  474  ?    ?   ?   A . n 
A 1 464  GLY 464  475  ?    ?   ?   A . n 
A 1 465  LYS 465  476  ?    ?   ?   A . n 
A 1 466  TRP 466  477  ?    ?   ?   A . n 
A 1 467  ALA 467  478  ?    ?   ?   A . n 
A 1 468  GLN 468  479  ?    ?   ?   A . n 
A 1 469  ALA 469  480  ?    ?   ?   A . n 
A 1 470  ALA 470  481  ?    ?   ?   A . n 
A 1 471  ALA 471  482  ?    ?   ?   A . n 
A 1 472  LEU 472  483  ?    ?   ?   A . n 
A 1 473  GLN 473  484  ?    ?   ?   A . n 
A 1 474  ARG 474  485  ?    ?   ?   A . n 
A 1 475  GLN 475  486  ?    ?   ?   A . n 
A 1 476  ARG 476  487  ?    ?   ?   A . n 
A 1 477  LEU 477  488  ?    ?   ?   A . n 
A 1 478  ALA 478  489  ?    ?   ?   A . n 
A 1 479  LEU 479  490  ?    ?   ?   A . n 
A 1 480  ASP 480  491  ?    ?   ?   A . n 
A 1 481  PRO 481  492  ?    ?   ?   A . n 
A 1 482  GLY 482  493  ?    ?   ?   A . n 
A 1 483  SER 483  494  ?    ?   ?   A . n 
A 1 484  VAL 484  495  ?    ?   ?   A . n 
A 1 485  TRP 485  496  ?    ?   ?   A . n 
A 1 486  ILE 486  497  ?    ?   ?   A . n 
A 1 487  THR 487  498  ?    ?   ?   A . n 
A 1 488  TYR 488  499  ?    ?   ?   A . n 
A 1 489  ARG 489  500  ?    ?   ?   A . n 
A 1 490  LEU 490  501  ?    ?   ?   A . n 
A 1 491  SER 491  502  ?    ?   ?   A . n 
A 1 492  GLN 492  503  ?    ?   ?   A . n 
A 1 493  ASP 493  504  ?    ?   ?   A . n 
A 1 494  LEU 494  505  ?    ?   ?   A . n 
A 1 495  TRP 495  506  ?    ?   ?   A . n 
A 1 496  GLN 496  507  ?    ?   ?   A . n 
A 1 497  ALA 497  508  ?    ?   ?   A . n 
A 1 498  GLY 498  509  ?    ?   ?   A . n 
A 1 499  GLN 499  510  ?    ?   ?   A . n 
A 1 500  ARG 500  511  ?    ?   ?   A . n 
A 1 501  SER 501  512  ?    ?   ?   A . n 
A 1 502  GLN 502  513  ?    ?   ?   A . n 
A 1 503  ALA 503  514  ?    ?   ?   A . n 
A 1 504  ASP 504  515  ?    ?   ?   A . n 
A 1 505  THR 505  516  ?    ?   ?   A . n 
A 1 506  LEU 506  517  ?    ?   ?   A . n 
A 1 507  MET 507  518  ?    ?   ?   A . n 
A 1 508  ARG 508  519  ?    ?   ?   A . n 
A 1 509  ASN 509  520  ?    ?   ?   A . n 
A 1 510  LEU 510  521  ?    ?   ?   A . n 
A 1 511  ALA 511  522  ?    ?   ?   A . n 
A 1 512  GLN 512  523  ?    ?   ?   A . n 
A 1 513  GLN 513  524  ?    ?   ?   A . n 
A 1 514  LYS 514  525  ?    ?   ?   A . n 
A 1 515  SER 515  526  ?    ?   ?   A . n 
A 1 516  ASN 516  527  ?    ?   ?   A . n 
A 1 517  ASP 517  528  ?    ?   ?   A . n 
A 1 518  PRO 518  529  ?    ?   ?   A . n 
A 1 519  GLU 519  530  ?    ?   ?   A . n 
A 1 520  GLN 520  531  ?    ?   ?   A . n 
A 1 521  VAL 521  532  ?    ?   ?   A . n 
A 1 522  TYR 522  533  ?    ?   ?   A . n 
A 1 523  ALA 523  534  ?    ?   ?   A . n 
A 1 524  TYR 524  535  ?    ?   ?   A . n 
A 1 525  GLY 525  536  ?    ?   ?   A . n 
A 1 526  LEU 526  537  ?    ?   ?   A . n 
A 1 527  TYR 527  538  ?    ?   ?   A . n 
A 1 528  LEU 528  539  ?    ?   ?   A . n 
A 1 529  SER 529  540  ?    ?   ?   A . n 
A 1 530  GLY 530  541  ?    ?   ?   A . n 
A 1 531  HIS 531  542  ?    ?   ?   A . n 
A 1 532  ASP 532  543  ?    ?   ?   A . n 
A 1 533  GLN 533  544  ?    ?   ?   A . n 
A 1 534  ASP 534  545  ?    ?   ?   A . n 
A 1 535  ARG 535  546  ?    ?   ?   A . n 
A 1 536  ALA 536  547  ?    ?   ?   A . n 
A 1 537  ALA 537  548  ?    ?   ?   A . n 
A 1 538  LEU 538  549  ?    ?   ?   A . n 
A 1 539  ALA 539  550  ?    ?   ?   A . n 
A 1 540  HIS 540  551  ?    ?   ?   A . n 
A 1 541  ILE 541  552  ?    ?   ?   A . n 
A 1 542  ASN 542  553  ?    ?   ?   A . n 
A 1 543  SER 543  554  ?    ?   ?   A . n 
A 1 544  LEU 544  555  ?    ?   ?   A . n 
A 1 545  PRO 545  556  ?    ?   ?   A . n 
A 1 546  ARG 546  557  ?    ?   ?   A . n 
A 1 547  ALA 547  558  ?    ?   ?   A . n 
A 1 548  GLN 548  559  ?    ?   ?   A . n 
A 1 549  TRP 549  560  ?    ?   ?   A . n 
A 1 550  ASN 550  561  ?    ?   ?   A . n 
A 1 551  SER 551  562  ?    ?   ?   A . n 
A 1 552  ASN 552  563  ?    ?   ?   A . n 
A 1 553  ILE 553  564  ?    ?   ?   A . n 
A 1 554  GLN 554  565  ?    ?   ?   A . n 
A 1 555  GLU 555  566  ?    ?   ?   A . n 
A 1 556  LEU 556  567  ?    ?   ?   A . n 
A 1 557  VAL 557  568  ?    ?   ?   A . n 
A 1 558  ASN 558  569  ?    ?   ?   A . n 
A 1 559  ARG 559  570  ?    ?   ?   A . n 
A 1 560  LEU 560  571  571  LEU LEU A . n 
A 1 561  GLN 561  572  572  GLN GLN A . n 
A 1 562  SER 562  573  573  SER SER A . n 
A 1 563  ASP 563  574  574  ASP ASP A . n 
A 1 564  GLN 564  575  575  GLN GLN A . n 
A 1 565  VAL 565  576  576  VAL VAL A . n 
A 1 566  LEU 566  577  577  LEU LEU A . n 
A 1 567  GLU 567  578  578  GLU GLU A . n 
A 1 568  THR 568  579  579  THR THR A . n 
A 1 569  ALA 569  580  580  ALA ALA A . n 
A 1 570  ASN 570  581  581  ASN ASN A . n 
A 1 571  ARG 571  582  582  ARG ARG A . n 
A 1 572  LEU 572  583  583  LEU LEU A . n 
A 1 573  ARG 573  584  584  ARG ARG A . n 
A 1 574  GLU 574  585  585  GLU GLU A . n 
A 1 575  SER 575  586  586  SER SER A . n 
A 1 576  GLY 576  587  587  GLY GLY A . n 
A 1 577  LYS 577  588  588  LYS LYS A . n 
A 1 578  GLU 578  589  589  GLU GLU A . n 
A 1 579  ALA 579  590  590  ALA ALA A . n 
A 1 580  GLU 580  591  591  GLU GLU A . n 
A 1 581  ALA 581  592  592  ALA ALA A . n 
A 1 582  GLU 582  593  593  GLU GLU A . n 
A 1 583  ALA 583  594  594  ALA ALA A . n 
A 1 584  MET 584  595  595  MET MET A . n 
A 1 585  LEU 585  596  596  LEU LEU A . n 
A 1 586  ARG 586  597  597  ARG ARG A . n 
A 1 587  GLN 587  598  598  GLN GLN A . n 
A 1 588  GLN 588  599  599  GLN GLN A . n 
A 1 589  PRO 589  600  600  PRO PRO A . n 
A 1 590  PRO 590  601  601  PRO PRO A . n 
A 1 591  SER 591  602  602  SER SER A . n 
A 1 592  THR 592  603  603  THR THR A . n 
A 1 593  ARG 593  604  604  ARG ARG A . n 
A 1 594  ILE 594  605  605  ILE ILE A . n 
A 1 595  ASP 595  606  606  ASP ASP A . n 
A 1 596  LEU 596  607  607  LEU LEU A . n 
A 1 597  THR 597  608  608  THR THR A . n 
A 1 598  LEU 598  609  609  LEU LEU A . n 
A 1 599  ALA 599  610  610  ALA ALA A . n 
A 1 600  ASP 600  611  611  ASP ASP A . n 
A 1 601  TRP 601  612  612  TRP TRP A . n 
A 1 602  ALA 602  613  613  ALA ALA A . n 
A 1 603  GLN 603  614  614  GLN GLN A . n 
A 1 604  GLN 604  615  615  GLN GLN A . n 
A 1 605  ARG 605  616  616  ARG ARG A . n 
A 1 606  ARG 606  617  617  ARG ARG A . n 
A 1 607  ASP 607  618  618  ASP ASP A . n 
A 1 608  TYR 608  619  619  TYR TYR A . n 
A 1 609  THR 609  620  620  THR THR A . n 
A 1 610  ALA 610  621  621  ALA ALA A . n 
A 1 611  ALA 611  622  622  ALA ALA A . n 
A 1 612  ARG 612  623  623  ARG ARG A . n 
A 1 613  ALA 613  624  624  ALA ALA A . n 
A 1 614  ALA 614  625  625  ALA ALA A . n 
A 1 615  TYR 615  626  626  TYR TYR A . n 
A 1 616  GLN 616  627  627  GLN GLN A . n 
A 1 617  ASN 617  628  628  ASN ASN A . n 
A 1 618  VAL 618  629  629  VAL VAL A . n 
A 1 619  LEU 619  630  630  LEU LEU A . n 
A 1 620  THR 620  631  631  THR THR A . n 
A 1 621  ARG 621  632  632  ARG ARG A . n 
A 1 622  GLU 622  633  633  GLU GLU A . n 
A 1 623  PRO 623  634  634  PRO PRO A . n 
A 1 624  ALA 624  635  635  ALA ALA A . n 
A 1 625  ASN 625  636  636  ASN ASN A . n 
A 1 626  ALA 626  637  637  ALA ALA A . n 
A 1 627  ASP 627  638  638  ASP ASP A . n 
A 1 628  ALA 628  639  639  ALA ALA A . n 
A 1 629  ILE 629  640  640  ILE ILE A . n 
A 1 630  LEU 630  641  641  LEU LEU A . n 
A 1 631  GLY 631  642  642  GLY GLY A . n 
A 1 632  LEU 632  643  643  LEU LEU A . n 
A 1 633  THR 633  644  644  THR THR A . n 
A 1 634  GLU 634  645  645  GLU GLU A . n 
A 1 635  VAL 635  646  646  VAL VAL A . n 
A 1 636  ASP 636  647  647  ASP ASP A . n 
A 1 637  ILE 637  648  648  ILE ILE A . n 
A 1 638  ALA 638  649  649  ALA ALA A . n 
A 1 639  ALA 639  650  650  ALA ALA A . n 
A 1 640  GLY 640  651  651  GLY GLY A . n 
A 1 641  ASP 641  652  652  ASP ASP A . n 
A 1 642  LYS 642  653  653  LYS LYS A . n 
A 1 643  ALA 643  654  654  ALA ALA A . n 
A 1 644  ALA 644  655  655  ALA ALA A . n 
A 1 645  ALA 645  656  656  ALA ALA A . n 
A 1 646  ARG 646  657  657  ARG ARG A . n 
A 1 647  SER 647  658  658  SER SER A . n 
A 1 648  GLN 648  659  659  GLN GLN A . n 
A 1 649  LEU 649  660  660  LEU LEU A . n 
A 1 650  ALA 650  661  661  ALA ALA A . n 
A 1 651  LYS 651  662  662  LYS LYS A . n 
A 1 652  LEU 652  663  663  LEU LEU A . n 
A 1 653  PRO 653  664  664  PRO PRO A . n 
A 1 654  ALA 654  665  665  ALA ALA A . n 
A 1 655  THR 655  666  666  THR THR A . n 
A 1 656  ASP 656  667  667  ASP ASP A . n 
A 1 657  ASN 657  668  668  ASN ASN A . n 
A 1 658  ALA 658  669  669  ALA ALA A . n 
A 1 659  SER 659  670  670  SER SER A . n 
A 1 660  LEU 660  671  671  LEU LEU A . n 
A 1 661  ASN 661  672  672  ASN ASN A . n 
A 1 662  THR 662  673  673  THR THR A . n 
A 1 663  GLN 663  674  674  GLN GLN A . n 
A 1 664  ARG 664  675  675  ARG ARG A . n 
A 1 665  ARG 665  676  676  ARG ARG A . n 
A 1 666  VAL 666  677  677  VAL VAL A . n 
A 1 667  ALA 667  678  678  ALA ALA A . n 
A 1 668  LEU 668  679  679  LEU LEU A . n 
A 1 669  ALA 669  680  680  ALA ALA A . n 
A 1 670  GLN 670  681  681  GLN GLN A . n 
A 1 671  ALA 671  682  682  ALA ALA A . n 
A 1 672  GLN 672  683  683  GLN GLN A . n 
A 1 673  LEU 673  684  684  LEU LEU A . n 
A 1 674  GLY 674  685  685  GLY GLY A . n 
A 1 675  ASP 675  686  686  ASP ASP A . n 
A 1 676  THR 676  687  687  THR THR A . n 
A 1 677  ALA 677  688  688  ALA ALA A . n 
A 1 678  ALA 678  689  689  ALA ALA A . n 
A 1 679  ALA 679  690  690  ALA ALA A . n 
A 1 680  GLN 680  691  691  GLN GLN A . n 
A 1 681  ARG 681  692  692  ARG ARG A . n 
A 1 682  THR 682  693  693  THR THR A . n 
A 1 683  PHE 683  694  694  PHE PHE A . n 
A 1 684  ASN 684  695  695  ASN ASN A . n 
A 1 685  LYS 685  696  696  LYS LYS A . n 
A 1 686  LEU 686  697  697  LEU LEU A . n 
A 1 687  ILE 687  698  698  ILE ILE A . n 
A 1 688  PRO 688  699  699  PRO PRO A . n 
A 1 689  GLN 689  700  700  GLN GLN A . n 
A 1 690  ALA 690  701  701  ALA ALA A . n 
A 1 691  LYS 691  702  702  LYS LYS A . n 
A 1 692  SER 692  703  703  SER SER A . n 
A 1 693  GLN 693  704  704  GLN GLN A . n 
A 1 694  PRO 694  705  705  PRO PRO A . n 
A 1 695  PRO 695  706  706  PRO PRO A . n 
A 1 696  SER 696  707  707  SER SER A . n 
A 1 697  MET 697  708  708  MET MET A . n 
A 1 698  GLU 698  709  709  GLU GLU A . n 
A 1 699  SER 699  710  710  SER SER A . n 
A 1 700  ALA 700  711  711  ALA ALA A . n 
A 1 701  MET 701  712  712  MET MET A . n 
A 1 702  VAL 702  713  713  VAL VAL A . n 
A 1 703  LEU 703  714  714  LEU LEU A . n 
A 1 704  ARG 704  715  715  ARG ARG A . n 
A 1 705  ASP 705  716  716  ASP ASP A . n 
A 1 706  GLY 706  717  717  GLY GLY A . n 
A 1 707  ALA 707  718  718  ALA ALA A . n 
A 1 708  LYS 708  719  719  LYS LYS A . n 
A 1 709  PHE 709  720  720  PHE PHE A . n 
A 1 710  GLU 710  721  721  GLU GLU A . n 
A 1 711  ALA 711  722  722  ALA ALA A . n 
A 1 712  GLN 712  723  723  GLN GLN A . n 
A 1 713  ALA 713  724  724  ALA ALA A . n 
A 1 714  GLY 714  725  725  GLY GLY A . n 
A 1 715  ASP 715  726  726  ASP ASP A . n 
A 1 716  PRO 716  727  727  PRO PRO A . n 
A 1 717  THR 717  728  728  THR THR A . n 
A 1 718  GLN 718  729  729  GLN GLN A . n 
A 1 719  ALA 719  730  730  ALA ALA A . n 
A 1 720  LEU 720  731  731  LEU LEU A . n 
A 1 721  GLU 721  732  732  GLU GLU A . n 
A 1 722  THR 722  733  733  THR THR A . n 
A 1 723  TYR 723  734  734  TYR TYR A . n 
A 1 724  LYS 724  735  735  LYS LYS A . n 
A 1 725  ASP 725  736  736  ASP ASP A . n 
A 1 726  ALA 726  737  737  ALA ALA A . n 
A 1 727  MET 727  738  738  MET MET A . n 
A 1 728  VAL 728  739  739  VAL VAL A . n 
A 1 729  ALA 729  740  740  ALA ALA A . n 
A 1 730  SER 730  741  741  SER SER A . n 
A 1 731  GLY 731  742  742  GLY GLY A . n 
A 1 732  VAL 732  743  743  VAL VAL A . n 
A 1 733  THR 733  744  744  THR THR A . n 
A 1 734  THR 734  745  745  THR THR A . n 
A 1 735  THR 735  746  746  THR THR A . n 
A 1 736  ARG 736  747  747  ARG ARG A . n 
A 1 737  PRO 737  748  748  PRO PRO A . n 
A 1 738  GLN 738  749  749  GLN GLN A . n 
A 1 739  ASP 739  750  750  ASP ASP A . n 
A 1 740  ASN 740  751  751  ASN ASN A . n 
A 1 741  ASP 741  752  752  ASP ASP A . n 
A 1 742  THR 742  753  753  THR THR A . n 
A 1 743  PHE 743  754  754  PHE PHE A . n 
A 1 744  THR 744  755  755  THR THR A . n 
A 1 745  ARG 745  756  756  ARG ARG A . n 
A 1 746  LEU 746  757  757  LEU LEU A . n 
A 1 747  THR 747  758  758  THR THR A . n 
A 1 748  ARG 748  759  759  ARG ARG A . n 
A 1 749  ASN 749  760  760  ASN ASN A . n 
A 1 750  ASP 750  761  761  ASP ASP A . n 
A 1 751  GLU 751  762  762  GLU GLU A . n 
A 1 752  LYS 752  763  763  LYS LYS A . n 
A 1 753  ASP 753  764  764  ASP ASP A . n 
A 1 754  ASP 754  765  765  ASP ASP A . n 
A 1 755  TRP 755  766  766  TRP TRP A . n 
A 1 756  LEU 756  767  767  LEU LEU A . n 
A 1 757  LYS 757  768  768  LYS LYS A . n 
A 1 758  ARG 758  769  769  ARG ARG A . n 
A 1 759  GLY 759  770  770  GLY GLY A . n 
A 1 760  VAL 760  771  771  VAL VAL A . n 
A 1 761  ARG 761  772  772  ARG ARG A . n 
A 1 762  SER 762  773  773  SER SER A . n 
A 1 763  ASP 763  774  774  ASP ASP A . n 
A 1 764  ALA 764  775  775  ALA ALA A . n 
A 1 765  ALA 765  776  776  ALA ALA A . n 
A 1 766  ASP 766  777  777  ASP ASP A . n 
A 1 767  LEU 767  778  778  LEU LEU A . n 
A 1 768  TYR 768  779  779  TYR TYR A . n 
A 1 769  ARG 769  780  780  ARG ARG A . n 
A 1 770  GLN 770  781  781  GLN GLN A . n 
A 1 771  GLN 771  782  782  GLN GLN A . n 
A 1 772  ASP 772  783  783  ASP ASP A . n 
A 1 773  LEU 773  784  784  LEU LEU A . n 
A 1 774  ASN 774  785  785  ASN ASN A . n 
A 1 775  VAL 775  786  786  VAL VAL A . n 
A 1 776  THR 776  787  787  THR THR A . n 
A 1 777  LEU 777  788  788  LEU LEU A . n 
A 1 778  GLU 778  789  789  GLU GLU A . n 
A 1 779  HIS 779  790  790  HIS HIS A . n 
A 1 780  ASP 780  791  791  ASP ASP A . n 
A 1 781  TYR 781  792  792  TYR TYR A . n 
A 1 782  TRP 782  793  793  TRP TRP A . n 
A 1 783  GLY 783  794  794  GLY GLY A . n 
A 1 784  SER 784  795  795  SER SER A . n 
A 1 785  SER 785  796  796  SER SER A . n 
A 1 786  GLY 786  797  797  GLY GLY A . n 
A 1 787  THR 787  798  798  THR THR A . n 
A 1 788  GLY 788  799  799  GLY GLY A . n 
A 1 789  GLY 789  800  800  GLY GLY A . n 
A 1 790  TYR 790  801  801  TYR TYR A . n 
A 1 791  SER 791  802  802  SER SER A . n 
A 1 792  ASP 792  803  803  ASP ASP A . n 
A 1 793  LEU 793  804  804  LEU LEU A . n 
A 1 794  LYS 794  805  805  LYS LYS A . n 
A 1 795  ALA 795  806  806  ALA ALA A . n 
A 1 796  HIS 796  807  807  HIS HIS A . n 
A 1 797  THR 797  808  808  THR THR A . n 
A 1 798  THR 798  809  809  THR THR A . n 
A 1 799  MET 799  810  810  MET MET A . n 
A 1 800  LEU 800  811  811  LEU LEU A . n 
A 1 801  GLN 801  812  812  GLN GLN A . n 
A 1 802  VAL 802  813  813  VAL VAL A . n 
A 1 803  ASP 803  814  814  ASP ASP A . n 
A 1 804  ALA 804  815  815  ALA ALA A . n 
A 1 805  PRO 805  816  816  PRO PRO A . n 
A 1 806  TYR 806  817  817  TYR TYR A . n 
A 1 807  SER 807  818  818  SER SER A . n 
A 1 808  ASP 808  819  819  ASP ASP A . n 
A 1 809  GLY 809  820  820  GLY GLY A . n 
A 1 810  ARG 810  821  821  ARG ARG A . n 
A 1 811  MET 811  822  822  MET MET A . n 
A 1 812  PHE 812  823  823  PHE PHE A . n 
A 1 813  PHE 813  824  824  PHE PHE A . n 
A 1 814  ARG 814  825  825  ARG ARG A . n 
A 1 815  SER 815  826  826  SER SER A . n 
A 1 816  ASP 816  827  827  ASP ASP A . n 
A 1 817  PHE 817  828  828  PHE PHE A . n 
A 1 818  VAL 818  829  829  VAL VAL A . n 
A 1 819  ASN 819  830  830  ASN ASN A . n 
A 1 820  MET 820  831  831  MET MET A . n 
A 1 821  ASN 821  832  832  ASN ASN A . n 
A 1 822  VAL 822  833  833  VAL VAL A . n 
A 1 823  GLY 823  834  834  GLY GLY A . n 
A 1 824  SER 824  835  835  SER SER A . n 
A 1 825  PHE 825  836  836  PHE PHE A . n 
A 1 826  SER 826  837  837  SER SER A . n 
A 1 827  THR 827  838  838  THR THR A . n 
A 1 828  ASN 828  839  839  ASN ASN A . n 
A 1 829  ALA 829  840  840  ALA ALA A . n 
A 1 830  ASP 830  841  841  ASP ASP A . n 
A 1 831  GLY 831  842  842  GLY GLY A . n 
A 1 832  LYS 832  843  843  LYS LYS A . n 
A 1 833  TRP 833  844  844  TRP TRP A . n 
A 1 834  ASP 834  845  845  ASP ASP A . n 
A 1 835  ASP 835  846  846  ASP ASP A . n 
A 1 836  ASN 836  847  847  ASN ASN A . n 
A 1 837  TRP 837  848  848  TRP TRP A . n 
A 1 838  GLY 838  849  849  GLY GLY A . n 
A 1 839  THR 839  850  850  THR THR A . n 
A 1 840  CYS 840  851  851  CYS CYS A . n 
A 1 841  THR 841  852  852  THR THR A . n 
A 1 842  LEU 842  853  853  LEU LEU A . n 
A 1 843  GLN 843  854  854  GLN GLN A . n 
A 1 844  ASP 844  855  855  ASP ASP A . n 
A 1 845  CYS 845  856  856  CYS CYS A . n 
A 1 846  SER 846  857  857  SER SER A . n 
A 1 847  GLY 847  858  858  GLY GLY A . n 
A 1 848  ASN 848  859  859  ASN ASN A . n 
A 1 849  ARG 849  860  860  ARG ARG A . n 
A 1 850  SER 850  861  861  SER SER A . n 
A 1 851  GLN 851  862  862  GLN GLN A . n 
A 1 852  SER 852  863  863  SER SER A . n 
A 1 853  ASP 853  864  864  ASP ASP A . n 
A 1 854  SER 854  865  865  SER SER A . n 
A 1 855  GLY 855  866  866  GLY GLY A . n 
A 1 856  ALA 856  867  867  ALA ALA A . n 
A 1 857  SER 857  868  868  SER SER A . n 
A 1 858  VAL 858  869  869  VAL VAL A . n 
A 1 859  ALA 859  870  870  ALA ALA A . n 
A 1 860  VAL 860  871  871  VAL VAL A . n 
A 1 861  GLY 861  872  872  GLY GLY A . n 
A 1 862  TRP 862  873  873  TRP TRP A . n 
A 1 863  ARG 863  874  874  ARG ARG A . n 
A 1 864  ASN 864  875  875  ASN ASN A . n 
A 1 865  ASP 865  876  876  ASP ASP A . n 
A 1 866  VAL 866  877  877  VAL VAL A . n 
A 1 867  TRP 867  878  878  TRP TRP A . n 
A 1 868  SER 868  879  879  SER SER A . n 
A 1 869  TRP 869  880  880  TRP TRP A . n 
A 1 870  ASP 870  881  881  ASP ASP A . n 
A 1 871  ILE 871  882  882  ILE ILE A . n 
A 1 872  GLY 872  883  883  GLY GLY A . n 
A 1 873  THR 873  884  884  THR THR A . n 
A 1 874  THR 874  885  885  THR THR A . n 
A 1 875  PRO 875  886  886  PRO PRO A . n 
A 1 876  MET 876  887  887  MET MET A . n 
A 1 877  GLY 877  888  888  GLY GLY A . n 
A 1 878  PHE 878  889  889  PHE PHE A . n 
A 1 879  ASN 879  890  890  ASN ASN A . n 
A 1 880  VAL 880  891  891  VAL VAL A . n 
A 1 881  VAL 881  892  892  VAL VAL A . n 
A 1 882  ASP 882  893  893  ASP ASP A . n 
A 1 883  VAL 883  894  894  VAL VAL A . n 
A 1 884  VAL 884  895  895  VAL VAL A . n 
A 1 885  GLY 885  896  896  GLY GLY A . n 
A 1 886  GLY 886  897  897  GLY GLY A . n 
A 1 887  ILE 887  898  898  ILE ILE A . n 
A 1 888  SER 888  899  899  SER SER A . n 
A 1 889  TYR 889  900  900  TYR TYR A . n 
A 1 890  SER 890  901  901  SER SER A . n 
A 1 891  ASP 891  902  902  ASP ASP A . n 
A 1 892  ASP 892  903  903  ASP ASP A . n 
A 1 893  ILE 893  904  904  ILE ILE A . n 
A 1 894  GLY 894  905  905  GLY GLY A . n 
A 1 895  PRO 895  906  906  PRO PRO A . n 
A 1 896  LEU 896  907  907  LEU LEU A . n 
A 1 897  GLY 897  908  908  GLY GLY A . n 
A 1 898  TYR 898  909  909  TYR TYR A . n 
A 1 899  THR 899  910  910  THR THR A . n 
A 1 900  VAL 900  911  911  VAL VAL A . n 
A 1 901  ASN 901  912  912  ASN ASN A . n 
A 1 902  ALA 902  913  913  ALA ALA A . n 
A 1 903  HIS 903  914  914  HIS HIS A . n 
A 1 904  ARG 904  915  915  ARG ARG A . n 
A 1 905  ARG 905  916  916  ARG ARG A . n 
A 1 906  PRO 906  917  917  PRO PRO A . n 
A 1 907  ILE 907  918  918  ILE ILE A . n 
A 1 908  SER 908  919  919  SER SER A . n 
A 1 909  SER 909  920  920  SER SER A . n 
A 1 910  SER 910  921  921  SER SER A . n 
A 1 911  LEU 911  922  922  LEU LEU A . n 
A 1 912  LEU 912  923  923  LEU LEU A . n 
A 1 913  ALA 913  924  924  ALA ALA A . n 
A 1 914  PHE 914  925  925  PHE PHE A . n 
A 1 915  GLY 915  926  926  GLY GLY A . n 
A 1 916  GLY 916  927  927  GLY GLY A . n 
A 1 917  GLN 917  928  928  GLN GLN A . n 
A 1 918  LYS 918  929  929  LYS LYS A . n 
A 1 919  ASP 919  930  930  ASP ASP A . n 
A 1 920  SER 920  931  931  SER SER A . n 
A 1 921  PRO 921  932  932  PRO PRO A . n 
A 1 922  SER 922  933  933  SER SER A . n 
A 1 923  ASN 923  934  934  ASN ASN A . n 
A 1 924  THR 924  935  935  THR THR A . n 
A 1 925  GLY 925  936  936  GLY GLY A . n 
A 1 926  LYS 926  937  937  LYS LYS A . n 
A 1 927  LYS 927  938  938  LYS LYS A . n 
A 1 928  TRP 928  939  939  TRP TRP A . n 
A 1 929  GLY 929  940  940  GLY GLY A . n 
A 1 930  GLY 930  941  941  GLY GLY A . n 
A 1 931  VAL 931  942  942  VAL VAL A . n 
A 1 932  ARG 932  943  943  ARG ARG A . n 
A 1 933  ALA 933  944  944  ALA ALA A . n 
A 1 934  ASP 934  945  945  ASP ASP A . n 
A 1 935  GLY 935  946  946  GLY GLY A . n 
A 1 936  VAL 936  947  947  VAL VAL A . n 
A 1 937  GLY 937  948  948  GLY GLY A . n 
A 1 938  LEU 938  949  949  LEU LEU A . n 
A 1 939  SER 939  950  950  SER SER A . n 
A 1 940  LEU 940  951  951  LEU LEU A . n 
A 1 941  SER 941  952  952  SER SER A . n 
A 1 942  TYR 942  953  953  TYR TYR A . n 
A 1 943  ASP 943  954  954  ASP ASP A . n 
A 1 944  LYS 944  955  955  LYS LYS A . n 
A 1 945  GLY 945  956  956  GLY GLY A . n 
A 1 946  GLU 946  957  957  GLU GLU A . n 
A 1 947  ALA 947  958  958  ALA ALA A . n 
A 1 948  ASN 948  959  959  ASN ASN A . n 
A 1 949  GLY 949  960  960  GLY GLY A . n 
A 1 950  VAL 950  961  961  VAL VAL A . n 
A 1 951  TRP 951  962  962  TRP TRP A . n 
A 1 952  ALA 952  963  963  ALA ALA A . n 
A 1 953  SER 953  964  964  SER SER A . n 
A 1 954  LEU 954  965  965  LEU LEU A . n 
A 1 955  SER 955  966  966  SER SER A . n 
A 1 956  GLY 956  967  967  GLY GLY A . n 
A 1 957  ASP 957  968  968  ASP ASP A . n 
A 1 958  GLN 958  969  969  GLN GLN A . n 
A 1 959  LEU 959  970  970  LEU LEU A . n 
A 1 960  THR 960  971  971  THR THR A . n 
A 1 961  GLY 961  972  972  GLY GLY A . n 
A 1 962  LYS 962  973  973  LYS LYS A . n 
A 1 963  ASN 963  974  974  ASN ASN A . n 
A 1 964  VAL 964  975  975  VAL VAL A . n 
A 1 965  GLU 965  976  976  GLU GLU A . n 
A 1 966  ASP 966  977  977  ASP ASP A . n 
A 1 967  ASN 967  978  978  ASN ASN A . n 
A 1 968  TRP 968  979  979  TRP TRP A . n 
A 1 969  ARG 969  980  980  ARG ARG A . n 
A 1 970  VAL 970  981  981  VAL VAL A . n 
A 1 971  ARG 971  982  982  ARG ARG A . n 
A 1 972  TRP 972  983  983  TRP TRP A . n 
A 1 973  MET 973  984  984  MET MET A . n 
A 1 974  THR 974  985  985  THR THR A . n 
A 1 975  GLY 975  986  986  GLY GLY A . n 
A 1 976  TYR 976  987  987  TYR TYR A . n 
A 1 977  TYR 977  988  988  TYR TYR A . n 
A 1 978  TYR 978  989  989  TYR TYR A . n 
A 1 979  LYS 979  990  990  LYS LYS A . n 
A 1 980  VAL 980  991  991  VAL VAL A . n 
A 1 981  ILE 981  992  992  ILE ILE A . n 
A 1 982  ASN 982  993  993  ASN ASN A . n 
A 1 983  GLN 983  994  994  GLN GLN A . n 
A 1 984  ASN 984  995  995  ASN ASN A . n 
A 1 985  ASN 985  996  996  ASN ASN A . n 
A 1 986  ARG 986  997  997  ARG ARG A . n 
A 1 987  ARG 987  998  998  ARG ARG A . n 
A 1 988  VAL 988  999  999  VAL VAL A . n 
A 1 989  THR 989  1000 1000 THR THR A . n 
A 1 990  ILE 990  1001 1001 ILE ILE A . n 
A 1 991  GLY 991  1002 1002 GLY GLY A . n 
A 1 992  LEU 992  1003 1003 LEU LEU A . n 
A 1 993  ASN 993  1004 1004 ASN ASN A . n 
A 1 994  ASN 994  1005 1005 ASN ASN A . n 
A 1 995  MET 995  1006 1006 MET MET A . n 
A 1 996  ILE 996  1007 1007 ILE ILE A . n 
A 1 997  TRP 997  1008 1008 TRP TRP A . n 
A 1 998  HIS 998  1009 1009 HIS HIS A . n 
A 1 999  TYR 999  1010 1010 TYR TYR A . n 
A 1 1000 ASP 1000 1011 1011 ASP ASP A . n 
A 1 1001 LYS 1001 1012 1012 LYS LYS A . n 
A 1 1002 ASP 1002 1013 1013 ASP ASP A . n 
A 1 1003 LEU 1003 1014 1014 LEU LEU A . n 
A 1 1004 SER 1004 1015 1015 SER SER A . n 
A 1 1005 GLY 1005 1016 1016 GLY GLY A . n 
A 1 1006 TYR 1006 1017 1017 TYR TYR A . n 
A 1 1007 SER 1007 1018 1018 SER SER A . n 
A 1 1008 LEU 1008 1019 1019 LEU LEU A . n 
A 1 1009 GLY 1009 1020 1020 GLY GLY A . n 
A 1 1010 GLN 1010 1021 1021 GLN GLN A . n 
A 1 1011 GLY 1011 1022 1022 GLY GLY A . n 
A 1 1012 GLY 1012 1023 1023 GLY GLY A . n 
A 1 1013 TYR 1013 1024 1024 TYR TYR A . n 
A 1 1014 TYR 1014 1025 1025 TYR TYR A . n 
A 1 1015 SER 1015 1026 1026 SER SER A . n 
A 1 1016 PRO 1016 1027 1027 PRO PRO A . n 
A 1 1017 GLN 1017 1028 1028 GLN GLN A . n 
A 1 1018 GLU 1018 1029 1029 GLU GLU A . n 
A 1 1019 TYR 1019 1030 1030 TYR TYR A . n 
A 1 1020 LEU 1020 1031 1031 LEU LEU A . n 
A 1 1021 SER 1021 1032 1032 SER SER A . n 
A 1 1022 PHE 1022 1033 1033 PHE PHE A . n 
A 1 1023 ALA 1023 1034 1034 ALA ALA A . n 
A 1 1024 ILE 1024 1035 1035 ILE ILE A . n 
A 1 1025 PRO 1025 1036 1036 PRO PRO A . n 
A 1 1026 VAL 1026 1037 1037 VAL VAL A . n 
A 1 1027 MET 1027 1038 1038 MET MET A . n 
A 1 1028 TRP 1028 1039 1039 TRP TRP A . n 
A 1 1029 ARG 1029 1040 1040 ARG ARG A . n 
A 1 1030 GLU 1030 1041 1041 GLU GLU A . n 
A 1 1031 ARG 1031 1042 1042 ARG ARG A . n 
A 1 1032 THR 1032 1043 1043 THR THR A . n 
A 1 1033 GLU 1033 1044 1044 GLU GLU A . n 
A 1 1034 ASN 1034 1045 1045 ASN ASN A . n 
A 1 1035 TRP 1035 1046 1046 TRP TRP A . n 
A 1 1036 SER 1036 1047 1047 SER SER A . n 
A 1 1037 TRP 1037 1048 1048 TRP TRP A . n 
A 1 1038 GLU 1038 1049 1049 GLU GLU A . n 
A 1 1039 LEU 1039 1050 1050 LEU LEU A . n 
A 1 1040 GLY 1040 1051 1051 GLY GLY A . n 
A 1 1041 ALA 1041 1052 1052 ALA ALA A . n 
A 1 1042 SER 1042 1053 1053 SER SER A . n 
A 1 1043 GLY 1043 1054 1054 GLY GLY A . n 
A 1 1044 SER 1044 1055 1055 SER SER A . n 
A 1 1045 TRP 1045 1056 1056 TRP TRP A . n 
A 1 1046 SER 1046 1057 1057 SER SER A . n 
A 1 1047 HIS 1047 1058 1058 HIS HIS A . n 
A 1 1048 SER 1048 1059 1059 SER SER A . n 
A 1 1049 ARG 1049 1060 1060 ARG ARG A . n 
A 1 1050 THR 1050 1061 1061 THR THR A . n 
A 1 1051 LYS 1051 1062 1062 LYS LYS A . n 
A 1 1052 THR 1052 1063 1063 THR THR A . n 
A 1 1053 MET 1053 1064 1064 MET MET A . n 
A 1 1054 PRO 1054 1065 1065 PRO PRO A . n 
A 1 1055 ARG 1055 1066 1066 ARG ARG A . n 
A 1 1056 TYR 1056 1067 1067 TYR TYR A . n 
A 1 1057 PRO 1057 1068 1068 PRO PRO A . n 
A 1 1058 LEU 1058 1069 1069 LEU LEU A . n 
A 1 1059 MET 1059 1070 1070 MET MET A . n 
A 1 1060 ASN 1060 1071 1071 ASN ASN A . n 
A 1 1061 LEU 1061 1072 1072 LEU LEU A . n 
A 1 1062 ILE 1062 1073 1073 ILE ILE A . n 
A 1 1063 PRO 1063 1074 1074 PRO PRO A . n 
A 1 1064 THR 1064 1075 1075 THR THR A . n 
A 1 1065 ASP 1065 1076 1076 ASP ASP A . n 
A 1 1066 TRP 1066 1077 1077 TRP TRP A . n 
A 1 1067 GLN 1067 1078 1078 GLN GLN A . n 
A 1 1068 GLU 1068 1079 1079 GLU GLU A . n 
A 1 1069 GLU 1069 1080 1080 GLU GLU A . n 
A 1 1070 ALA 1070 1081 1081 ALA ALA A . n 
A 1 1071 ALA 1071 1082 1082 ALA ALA A . n 
A 1 1072 ARG 1072 1083 1083 ARG ARG A . n 
A 1 1073 GLN 1073 1084 1084 GLN GLN A . n 
A 1 1074 SER 1074 1085 1085 SER SER A . n 
A 1 1075 ASN 1075 1086 1086 ASN ASN A . n 
A 1 1076 ASP 1076 1087 1087 ASP ASP A . n 
A 1 1077 GLY 1077 1088 1088 GLY GLY A . n 
A 1 1078 GLY 1078 1089 1089 GLY GLY A . n 
A 1 1079 SER 1079 1090 1090 SER SER A . n 
A 1 1080 SER 1080 1091 1091 SER SER A . n 
A 1 1081 GLN 1081 1092 1092 GLN GLN A . n 
A 1 1082 GLY 1082 1093 1093 GLY GLY A . n 
A 1 1083 PHE 1083 1094 1094 PHE PHE A . n 
A 1 1084 GLY 1084 1095 1095 GLY GLY A . n 
A 1 1085 TYR 1085 1096 1096 TYR TYR A . n 
A 1 1086 THR 1086 1097 1097 THR THR A . n 
A 1 1087 ALA 1087 1098 1098 ALA ALA A . n 
A 1 1088 ARG 1088 1099 1099 ARG ARG A . n 
A 1 1089 ALA 1089 1100 1100 ALA ALA A . n 
A 1 1090 LEU 1090 1101 1101 LEU LEU A . n 
A 1 1091 LEU 1091 1102 1102 LEU LEU A . n 
A 1 1092 GLU 1092 1103 1103 GLU GLU A . n 
A 1 1093 ARG 1093 1104 1104 ARG ARG A . n 
A 1 1094 ARG 1094 1105 1105 ARG ARG A . n 
A 1 1095 VAL 1095 1106 1106 VAL VAL A . n 
A 1 1096 THR 1096 1107 1107 THR THR A . n 
A 1 1097 SER 1097 1108 1108 SER SER A . n 
A 1 1098 ASN 1098 1109 1109 ASN ASN A . n 
A 1 1099 TRP 1099 1110 1110 TRP TRP A . n 
A 1 1100 PHE 1100 1111 1111 PHE PHE A . n 
A 1 1101 VAL 1101 1112 1112 VAL VAL A . n 
A 1 1102 GLY 1102 1113 1113 GLY GLY A . n 
A 1 1103 THR 1103 1114 1114 THR THR A . n 
A 1 1104 ALA 1104 1115 1115 ALA ALA A . n 
A 1 1105 ILE 1105 1116 1116 ILE ILE A . n 
A 1 1106 ASP 1106 1117 1117 ASP ASP A . n 
A 1 1107 ILE 1107 1118 1118 ILE ILE A . n 
A 1 1108 GLN 1108 1119 1119 GLN GLN A . n 
A 1 1109 GLN 1109 1120 1120 GLN GLN A . n 
A 1 1110 ALA 1110 1121 1121 ALA ALA A . n 
A 1 1111 LYS 1111 1122 1122 LYS LYS A . n 
A 1 1112 ASP 1112 1123 1123 ASP ASP A . n 
A 1 1113 TYR 1113 1124 1124 TYR TYR A . n 
A 1 1114 ALA 1114 1125 1125 ALA ALA A . n 
A 1 1115 PRO 1115 1126 1126 PRO PRO A . n 
A 1 1116 SER 1116 1127 1127 SER SER A . n 
A 1 1117 HIS 1117 1128 1128 HIS HIS A . n 
A 1 1118 PHE 1118 1129 1129 PHE PHE A . n 
A 1 1119 LEU 1119 1130 1130 LEU LEU A . n 
A 1 1120 LEU 1120 1131 1131 LEU LEU A . n 
A 1 1121 TYR 1121 1132 1132 TYR TYR A . n 
A 1 1122 VAL 1122 1133 1133 VAL VAL A . n 
A 1 1123 ARG 1123 1134 1134 ARG ARG A . n 
A 1 1124 TYR 1124 1135 1135 TYR TYR A . n 
A 1 1125 SER 1125 1136 1136 SER SER A . n 
A 1 1126 ALA 1126 1137 1137 ALA ALA A . n 
A 1 1127 ALA 1127 1138 1138 ALA ALA A . n 
A 1 1128 GLY 1128 1139 1139 GLY GLY A . n 
A 1 1129 TRP 1129 1140 1140 TRP TRP A . n 
A 1 1130 GLN 1130 1141 1141 GLN GLN A . n 
A 1 1131 GLY 1131 1142 1142 GLY GLY A . n 
A 1 1132 ASP 1132 1143 1143 ASP ASP A . n 
A 1 1133 MET 1133 1144 1144 MET MET A . n 
A 1 1134 ASP 1134 1145 1145 ASP ASP A . n 
A 1 1135 LEU 1135 1146 1146 LEU LEU A . n 
A 1 1136 PRO 1136 1147 1147 PRO PRO A . n 
A 1 1137 PRO 1137 1148 1148 PRO PRO A . n 
A 1 1138 GLN 1138 1149 1149 GLN GLN A . n 
A 1 1139 PRO 1139 1150 1150 PRO PRO A . n 
A 1 1140 LEU 1140 1151 1151 LEU LEU A . n 
A 1 1141 ILE 1141 1152 1152 ILE ILE A . n 
A 1 1142 PRO 1142 1153 1153 PRO PRO A . n 
A 1 1143 TYR 1143 1154 1154 TYR TYR A . n 
A 1 1144 ALA 1144 1155 1155 ALA ALA A . n 
A 1 1145 ASP 1145 1156 1156 ASP ASP A . n 
A 1 1146 TRP 1146 1157 1157 TRP TRP A . n 
# 
loop_
_pdbx_branch_scheme.asym_id 
_pdbx_branch_scheme.entity_id 
_pdbx_branch_scheme.mon_id 
_pdbx_branch_scheme.num 
_pdbx_branch_scheme.pdb_asym_id 
_pdbx_branch_scheme.pdb_mon_id 
_pdbx_branch_scheme.pdb_seq_num 
_pdbx_branch_scheme.auth_asym_id 
_pdbx_branch_scheme.auth_mon_id 
_pdbx_branch_scheme.auth_seq_num 
_pdbx_branch_scheme.hetero 
B 2 BGC 1 B BGC 1 A BGC 1201 n 
B 2 BGC 2 B BGC 2 A BGC 1201 n 
B 2 BGC 3 B BGC 3 A BGC 1201 n 
B 2 BGC 4 B BGC 4 A BGC 1201 n 
# 
_pdbx_entity_instance_feature.ordinal        1 
_pdbx_entity_instance_feature.comp_id        BGC 
_pdbx_entity_instance_feature.asym_id        ? 
_pdbx_entity_instance_feature.seq_num        ? 
_pdbx_entity_instance_feature.auth_comp_id   BGC 
_pdbx_entity_instance_feature.auth_asym_id   ? 
_pdbx_entity_instance_feature.auth_seq_num   ? 
_pdbx_entity_instance_feature.feature_type   'SUBJECT OF INVESTIGATION' 
_pdbx_entity_instance_feature.details        ? 
# 
_cell.angle_alpha                  90.00 
_cell.angle_alpha_esd              ? 
_cell.angle_beta                   90.00 
_cell.angle_beta_esd               ? 
_cell.angle_gamma                  90.00 
_cell.angle_gamma_esd              ? 
_cell.entry_id                     9B8H 
_cell.details                      ? 
_cell.formula_units_Z              ? 
_cell.length_a                     1.00 
_cell.length_a_esd                 ? 
_cell.length_b                     1.00 
_cell.length_b_esd                 ? 
_cell.length_c                     1.00 
_cell.length_c_esd                 ? 
_cell.volume                       ? 
_cell.volume_esd                   ? 
_cell.Z_PDB                        ? 
_cell.reciprocal_angle_alpha       ? 
_cell.reciprocal_angle_beta        ? 
_cell.reciprocal_angle_gamma       ? 
_cell.reciprocal_angle_alpha_esd   ? 
_cell.reciprocal_angle_beta_esd    ? 
_cell.reciprocal_angle_gamma_esd   ? 
_cell.reciprocal_length_a          ? 
_cell.reciprocal_length_b          ? 
_cell.reciprocal_length_c          ? 
_cell.reciprocal_length_a_esd      ? 
_cell.reciprocal_length_b_esd      ? 
_cell.reciprocal_length_c_esd      ? 
_cell.pdbx_unique_axis             ? 
_cell.pdbx_esd_method              ? 
# 
_symmetry.entry_id                         9B8H 
_symmetry.cell_setting                     ? 
_symmetry.Int_Tables_number                1 
_symmetry.space_group_name_Hall            ? 
_symmetry.space_group_name_H-M             'P 1' 
_symmetry.pdbx_full_space_group_name_H-M   ? 
# 
_exptl.absorpt_coefficient_mu     ? 
_exptl.absorpt_correction_T_max   ? 
_exptl.absorpt_correction_T_min   ? 
_exptl.absorpt_correction_type    ? 
_exptl.absorpt_process_details    ? 
_exptl.entry_id                   9B8H 
_exptl.crystals_number            ? 
_exptl.details                    ? 
_exptl.method                     'ELECTRON MICROSCOPY' 
_exptl.method_details             ? 
# 
_struct.entry_id                     9B8H 
_struct.title                        'Cryo-EM structure of E. coli cellulose synthase subunit C with cellotetraose' 
_struct.pdbx_model_details           ? 
_struct.pdbx_formula_weight          ? 
_struct.pdbx_formula_weight_method   ? 
_struct.pdbx_model_type_details      ? 
_struct.pdbx_CASP_flag               N 
# 
_struct_keywords.entry_id        9B8H 
_struct_keywords.text            
'Porin, BcsC outer membrane protein, Tetra-tricopeptide (TPR) repeats, cellooligosaccharide, Membrane Protein' 
_struct_keywords.pdbx_keywords   'MEMBRANE PROTEIN' 
# 
loop_
_struct_asym.id 
_struct_asym.pdbx_blank_PDB_chainid_flag 
_struct_asym.pdbx_modified 
_struct_asym.entity_id 
_struct_asym.details 
A N N 1 ? 
B N N 2 ? 
# 
_struct_ref.id                         1 
_struct_ref.db_name                    UNP 
_struct_ref.db_code                    BCSC_ECOLI 
_struct_ref.pdbx_db_accession          P37650 
_struct_ref.pdbx_db_isoform            ? 
_struct_ref.entity_id                  1 
_struct_ref.pdbx_seq_one_letter_code   
;VEAAPTAQQQLLEQVRLGEATHREDLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKS
SRTTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIPARRGEAINQLKRINADAPGN
TGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGASKIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAE
QQKQLADPAFRARAQGLAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDPHSSNND
KWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVAMARKDYPAAERYYQQTLRMDSGNTN
AVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYR
LSQDLWQAGQRSQADTLMRNLAQQKSNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQELVNRLQSDQVLETA
NRLRESGKEAEAEAMLRQQPPSTRIDLTLADWAQQRRDYTAARAAYQNVLTREPANADAILGLTEVDIAAGDKAAARSQL
AKLPATDNASLNTQRRVALAQAQLGDTAAAQRTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPTQALETYKDAMVA
SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLQVDAPYSDG
RMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDCSGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISY
SDDIGPLGYTVNAHRRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTGKNVEDNWR
VRWMTGYYYKVINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEYLSFAIPVMWRERTENWSWELGASGSWSHSR
TKTMPRYPLMNLIPTDWQEEAARQSNDGGSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGW
QGDMDLPPQPLIPYADW
;
_struct_ref.pdbx_align_begin           21 
# 
_struct_ref_seq.align_id                      1 
_struct_ref_seq.ref_id                        1 
_struct_ref_seq.pdbx_PDB_id_code              9B8H 
_struct_ref_seq.pdbx_strand_id                A 
_struct_ref_seq.seq_align_beg                 10 
_struct_ref_seq.pdbx_seq_align_beg_ins_code   ? 
_struct_ref_seq.seq_align_end                 1146 
_struct_ref_seq.pdbx_seq_align_end_ins_code   ? 
_struct_ref_seq.pdbx_db_accession             P37650 
_struct_ref_seq.db_align_beg                  21 
_struct_ref_seq.pdbx_db_align_beg_ins_code    ? 
_struct_ref_seq.db_align_end                  1157 
_struct_ref_seq.pdbx_db_align_end_ins_code    ? 
_struct_ref_seq.pdbx_auth_seq_align_beg       21 
_struct_ref_seq.pdbx_auth_seq_align_end       1157 
# 
loop_
_struct_ref_seq_dif.align_id 
_struct_ref_seq_dif.pdbx_pdb_id_code 
_struct_ref_seq_dif.mon_id 
_struct_ref_seq_dif.pdbx_pdb_strand_id 
_struct_ref_seq_dif.seq_num 
_struct_ref_seq_dif.pdbx_pdb_ins_code 
_struct_ref_seq_dif.pdbx_seq_db_name 
_struct_ref_seq_dif.pdbx_seq_db_accession_code 
_struct_ref_seq_dif.db_mon_id 
_struct_ref_seq_dif.pdbx_seq_db_seq_num 
_struct_ref_seq_dif.details 
_struct_ref_seq_dif.pdbx_auth_seq_num 
_struct_ref_seq_dif.pdbx_ordinal 
1 9B8H MET A 1 ? UNP P37650 ? ? 'expression tag' 12 1 
1 9B8H HIS A 2 ? UNP P37650 ? ? 'expression tag' 13 2 
1 9B8H HIS A 3 ? UNP P37650 ? ? 'expression tag' 14 3 
1 9B8H HIS A 4 ? UNP P37650 ? ? 'expression tag' 15 4 
1 9B8H HIS A 5 ? UNP P37650 ? ? 'expression tag' 16 5 
1 9B8H HIS A 6 ? UNP P37650 ? ? 'expression tag' 17 6 
1 9B8H HIS A 7 ? UNP P37650 ? ? 'expression tag' 18 7 
1 9B8H HIS A 8 ? UNP P37650 ? ? 'expression tag' 19 8 
1 9B8H HIS A 9 ? UNP P37650 ? ? 'expression tag' 20 9 
# 
_pdbx_struct_assembly.id                   1 
_pdbx_struct_assembly.details              author_defined_assembly 
_pdbx_struct_assembly.method_details       ? 
_pdbx_struct_assembly.oligomeric_details   monomeric 
_pdbx_struct_assembly.oligomeric_count     1 
# 
_pdbx_struct_assembly_gen.assembly_id       1 
_pdbx_struct_assembly_gen.oper_expression   1 
_pdbx_struct_assembly_gen.asym_id_list      A,B 
# 
_pdbx_struct_assembly_auth_evidence.id                     1 
_pdbx_struct_assembly_auth_evidence.assembly_id            1 
_pdbx_struct_assembly_auth_evidence.experimental_support   'electron microscopy' 
_pdbx_struct_assembly_auth_evidence.details                'not applicable' 
# 
_pdbx_struct_oper_list.id                   1 
_pdbx_struct_oper_list.type                 'identity operation' 
_pdbx_struct_oper_list.name                 1_555 
_pdbx_struct_oper_list.symmetry_operation   ? 
_pdbx_struct_oper_list.matrix[1][1]         1.0000000000 
_pdbx_struct_oper_list.matrix[1][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[1][3]         0.0000000000 
_pdbx_struct_oper_list.vector[1]            0.0000000000 
_pdbx_struct_oper_list.matrix[2][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[2][2]         1.0000000000 
_pdbx_struct_oper_list.matrix[2][3]         0.0000000000 
_pdbx_struct_oper_list.vector[2]            0.0000000000 
_pdbx_struct_oper_list.matrix[3][1]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][2]         0.0000000000 
_pdbx_struct_oper_list.matrix[3][3]         1.0000000000 
_pdbx_struct_oper_list.vector[3]            0.0000000000 
# 
loop_
_struct_conf.conf_type_id 
_struct_conf.id 
_struct_conf.pdbx_PDB_helix_id 
_struct_conf.beg_label_comp_id 
_struct_conf.beg_label_asym_id 
_struct_conf.beg_label_seq_id 
_struct_conf.pdbx_beg_PDB_ins_code 
_struct_conf.end_label_comp_id 
_struct_conf.end_label_asym_id 
_struct_conf.end_label_seq_id 
_struct_conf.pdbx_end_PDB_ins_code 
_struct_conf.beg_auth_comp_id 
_struct_conf.beg_auth_asym_id 
_struct_conf.beg_auth_seq_id 
_struct_conf.end_auth_comp_id 
_struct_conf.end_auth_asym_id 
_struct_conf.end_auth_seq_id 
_struct_conf.pdbx_PDB_helix_class 
_struct_conf.details 
_struct_conf.pdbx_PDB_helix_length 
HELX_P HELX_P1  AA1 LEU A 560  ? ARG A 571  ? LEU A 571  ARG A 582  1 ? 12 
HELX_P HELX_P2  AA2 LYS A 577  ? ARG A 586  ? LYS A 588  ARG A 597  1 ? 10 
HELX_P HELX_P3  AA3 THR A 592  ? ARG A 605  ? THR A 603  ARG A 616  1 ? 14 
HELX_P HELX_P4  AA4 TYR A 608  ? ARG A 621  ? TYR A 619  ARG A 632  1 ? 14 
HELX_P HELX_P5  AA5 ASN A 625  ? GLY A 640  ? ASN A 636  GLY A 651  1 ? 16 
HELX_P HELX_P6  AA6 ASP A 641  ? LYS A 651  ? ASP A 652  LYS A 662  1 ? 11 
HELX_P HELX_P7  AA7 SER A 659  ? LEU A 673  ? SER A 670  LEU A 684  1 ? 15 
HELX_P HELX_P8  AA8 ASP A 675  ? GLN A 693  ? ASP A 686  GLN A 704  1 ? 19 
HELX_P HELX_P9  AA9 SER A 696  ? GLY A 714  ? SER A 707  GLY A 725  1 ? 19 
HELX_P HELX_P10 AB1 ASP A 715  ? GLY A 731  ? ASP A 726  GLY A 742  1 ? 17 
HELX_P HELX_P11 AB2 ASP A 739  ? THR A 747  ? ASP A 750  THR A 758  1 ? 9  
HELX_P HELX_P12 AB3 ASP A 754  ? GLN A 771  ? ASP A 765  GLN A 782  1 ? 18 
HELX_P HELX_P13 AB4 SER A 910  ? GLY A 915  ? SER A 921  GLY A 926  1 ? 6  
HELX_P HELX_P14 AB5 TRP A 1066 ? GLN A 1073 ? TRP A 1077 GLN A 1084 1 ? 8  
HELX_P HELX_P15 AB6 PRO A 1142 ? TRP A 1146 ? PRO A 1153 TRP A 1157 5 ? 5  
# 
_struct_conf_type.id          HELX_P 
_struct_conf_type.criteria    ? 
_struct_conf_type.reference   ? 
# 
loop_
_struct_conn.id 
_struct_conn.conn_type_id 
_struct_conn.pdbx_leaving_atom_flag 
_struct_conn.pdbx_PDB_id 
_struct_conn.ptnr1_label_asym_id 
_struct_conn.ptnr1_label_comp_id 
_struct_conn.ptnr1_label_seq_id 
_struct_conn.ptnr1_label_atom_id 
_struct_conn.pdbx_ptnr1_label_alt_id 
_struct_conn.pdbx_ptnr1_PDB_ins_code 
_struct_conn.pdbx_ptnr1_standard_comp_id 
_struct_conn.ptnr1_symmetry 
_struct_conn.ptnr2_label_asym_id 
_struct_conn.ptnr2_label_comp_id 
_struct_conn.ptnr2_label_seq_id 
_struct_conn.ptnr2_label_atom_id 
_struct_conn.pdbx_ptnr2_label_alt_id 
_struct_conn.pdbx_ptnr2_PDB_ins_code 
_struct_conn.ptnr1_auth_asym_id 
_struct_conn.ptnr1_auth_comp_id 
_struct_conn.ptnr1_auth_seq_id 
_struct_conn.ptnr2_auth_asym_id 
_struct_conn.ptnr2_auth_comp_id 
_struct_conn.ptnr2_auth_seq_id 
_struct_conn.ptnr2_symmetry 
_struct_conn.pdbx_ptnr3_label_atom_id 
_struct_conn.pdbx_ptnr3_label_seq_id 
_struct_conn.pdbx_ptnr3_label_comp_id 
_struct_conn.pdbx_ptnr3_label_asym_id 
_struct_conn.pdbx_ptnr3_label_alt_id 
_struct_conn.pdbx_ptnr3_PDB_ins_code 
_struct_conn.details 
_struct_conn.pdbx_dist_value 
_struct_conn.pdbx_value_order 
_struct_conn.pdbx_role 
disulf1 disulf ?    ? A CYS 840 SG ? ? ? 1_555 A CYS 845 SG ? ? A CYS 851 A CYS 856 1_555 ? ? ? ? ? ? ? 2.031 ? ? 
covale1 covale both ? B BGC .   O4 ? ? ? 1_555 B BGC .   C1 ? ? B BGC 1   B BGC 2   1_555 ? ? ? ? ? ? ? 1.440 ? ? 
covale2 covale both ? B BGC .   O4 ? ? ? 1_555 B BGC .   C1 ? ? B BGC 2   B BGC 3   1_555 ? ? ? ? ? ? ? 1.398 ? ? 
covale3 covale both ? B BGC .   O4 ? ? ? 1_555 B BGC .   C1 ? ? B BGC 3   B BGC 4   1_555 ? ? ? ? ? ? ? 1.412 ? ? 
# 
loop_
_struct_conn_type.id 
_struct_conn_type.criteria 
_struct_conn_type.reference 
disulf ? ? 
covale ? ? 
# 
_pdbx_modification_feature.ordinal                            1 
_pdbx_modification_feature.label_comp_id                      CYS 
_pdbx_modification_feature.label_asym_id                      A 
_pdbx_modification_feature.label_seq_id                       840 
_pdbx_modification_feature.label_alt_id                       ? 
_pdbx_modification_feature.modified_residue_label_comp_id     CYS 
_pdbx_modification_feature.modified_residue_label_asym_id     A 
_pdbx_modification_feature.modified_residue_label_seq_id      845 
_pdbx_modification_feature.modified_residue_label_alt_id      ? 
_pdbx_modification_feature.auth_comp_id                       CYS 
_pdbx_modification_feature.auth_asym_id                       A 
_pdbx_modification_feature.auth_seq_id                        851 
_pdbx_modification_feature.PDB_ins_code                       ? 
_pdbx_modification_feature.symmetry                           1_555 
_pdbx_modification_feature.modified_residue_auth_comp_id      CYS 
_pdbx_modification_feature.modified_residue_auth_asym_id      A 
_pdbx_modification_feature.modified_residue_auth_seq_id       856 
_pdbx_modification_feature.modified_residue_PDB_ins_code      ? 
_pdbx_modification_feature.modified_residue_symmetry          1_555 
_pdbx_modification_feature.comp_id_linking_atom               SG 
_pdbx_modification_feature.modified_residue_id_linking_atom   SG 
_pdbx_modification_feature.modified_residue_id                . 
_pdbx_modification_feature.ref_pcm_id                         . 
_pdbx_modification_feature.ref_comp_id                        . 
_pdbx_modification_feature.type                               None 
_pdbx_modification_feature.category                           'Disulfide bridge' 
# 
_struct_mon_prot_cis.pdbx_id                1 
_struct_mon_prot_cis.label_comp_id          LEU 
_struct_mon_prot_cis.label_seq_id           1135 
_struct_mon_prot_cis.label_asym_id          A 
_struct_mon_prot_cis.label_alt_id           . 
_struct_mon_prot_cis.pdbx_PDB_ins_code      ? 
_struct_mon_prot_cis.auth_comp_id           LEU 
_struct_mon_prot_cis.auth_seq_id            1146 
_struct_mon_prot_cis.auth_asym_id           A 
_struct_mon_prot_cis.pdbx_label_comp_id_2   PRO 
_struct_mon_prot_cis.pdbx_label_seq_id_2    1136 
_struct_mon_prot_cis.pdbx_label_asym_id_2   A 
_struct_mon_prot_cis.pdbx_PDB_ins_code_2    ? 
_struct_mon_prot_cis.pdbx_auth_comp_id_2    PRO 
_struct_mon_prot_cis.pdbx_auth_seq_id_2     1147 
_struct_mon_prot_cis.pdbx_auth_asym_id_2    A 
_struct_mon_prot_cis.pdbx_PDB_model_num     1 
_struct_mon_prot_cis.pdbx_omega_angle       -2.13 
# 
loop_
_struct_sheet.id 
_struct_sheet.type 
_struct_sheet.number_strands 
_struct_sheet.details 
AA1 ? 19 ? 
AA2 ? 2  ? 
AA3 ? 2  ? 
# 
loop_
_struct_sheet_order.sheet_id 
_struct_sheet_order.range_id_1 
_struct_sheet_order.range_id_2 
_struct_sheet_order.offset 
_struct_sheet_order.sense 
AA1 1  2  ? anti-parallel 
AA1 1  19 ? anti-parallel 
AA1 2  3  ? anti-parallel 
AA1 3  4  ? anti-parallel 
AA1 4  5  ? anti-parallel 
AA1 5  6  ? anti-parallel 
AA1 6  7  ? anti-parallel 
AA1 7  9  ? anti-parallel 
AA1 8  9  ? anti-parallel 
AA1 9  10 ? anti-parallel 
AA1 9  11 ? anti-parallel 
AA1 10 12 ? anti-parallel 
AA1 12 13 ? anti-parallel 
AA1 13 14 ? anti-parallel 
AA1 13 15 ? anti-parallel 
AA1 14 16 ? anti-parallel 
AA1 15 16 ? anti-parallel 
AA1 16 17 ? anti-parallel 
AA1 17 18 ? anti-parallel 
AA1 18 19 ? anti-parallel 
AA2 1  2  ? parallel      
AA3 1  2  ? anti-parallel 
# 
loop_
_struct_sheet_range.sheet_id 
_struct_sheet_range.id 
_struct_sheet_range.beg_label_comp_id 
_struct_sheet_range.beg_label_asym_id 
_struct_sheet_range.beg_label_seq_id 
_struct_sheet_range.pdbx_beg_PDB_ins_code 
_struct_sheet_range.end_label_comp_id 
_struct_sheet_range.end_label_asym_id 
_struct_sheet_range.end_label_seq_id 
_struct_sheet_range.pdbx_end_PDB_ins_code 
_struct_sheet_range.beg_auth_comp_id 
_struct_sheet_range.beg_auth_asym_id 
_struct_sheet_range.beg_auth_seq_id 
_struct_sheet_range.end_auth_comp_id 
_struct_sheet_range.end_auth_asym_id 
_struct_sheet_range.end_auth_seq_id 
AA1 1  ASN A 774  ? SER A 784  ? ASN A 785  SER A 795  
AA1 2  LEU A 793  ? TYR A 806  ? LEU A 804  TYR A 817  
AA1 3  GLY A 809  ? SER A 824  ? GLY A 820  SER A 835  
AA1 4  SER A 850  ? ARG A 863  ? SER A 861  ARG A 874  
AA1 5  TRP A 867  ? THR A 873  ? TRP A 878  THR A 884  
AA1 6  VAL A 883  ? ILE A 893  ? VAL A 894  ILE A 904  
AA1 7  LEU A 896  ? PRO A 906  ? LEU A 907  PRO A 917  
AA1 8  GLN A 917  ? LYS A 918  ? GLN A 928  LYS A 929  
AA1 9  LYS A 927  ? TYR A 942  ? LYS A 938  TYR A 953  
AA1 10 VAL A 950  ? ASP A 957  ? VAL A 961  ASP A 968  
AA1 11 LEU A 959  ? LYS A 962  ? LEU A 970  LYS A 973  
AA1 12 ARG A 969  ? ASN A 982  ? ARG A 980  ASN A 993  
AA1 13 ARG A 986  ? TRP A 997  ? ARG A 997  TRP A 1008 
AA1 14 GLU A 1018 ? VAL A 1026 ? GLU A 1029 VAL A 1037 
AA1 15 ARG A 1029 ? ARG A 1031 ? ARG A 1040 ARG A 1042 
AA1 16 TRP A 1035 ? ARG A 1049 ? TRP A 1046 ARG A 1060 
AA1 17 SER A 1079 ? ARG A 1094 ? SER A 1090 ARG A 1105 
AA1 18 TRP A 1099 ? GLN A 1109 ? TRP A 1110 GLN A 1120 
AA1 19 SER A 1116 ? SER A 1125 ? SER A 1127 SER A 1136 
AA2 1  TRP A 837  ? GLY A 838  ? TRP A 848  GLY A 849  
AA2 2  TYR A 1006 ? SER A 1007 ? TYR A 1017 SER A 1018 
AA3 1  MET A 1053 ? PRO A 1054 ? MET A 1064 PRO A 1065 
AA3 2  SER A 1074 ? ASN A 1075 ? SER A 1085 ASN A 1086 
# 
loop_
_pdbx_struct_sheet_hbond.sheet_id 
_pdbx_struct_sheet_hbond.range_id_1 
_pdbx_struct_sheet_hbond.range_id_2 
_pdbx_struct_sheet_hbond.range_1_label_atom_id 
_pdbx_struct_sheet_hbond.range_1_label_comp_id 
_pdbx_struct_sheet_hbond.range_1_label_asym_id 
_pdbx_struct_sheet_hbond.range_1_label_seq_id 
_pdbx_struct_sheet_hbond.range_1_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_1_auth_atom_id 
_pdbx_struct_sheet_hbond.range_1_auth_comp_id 
_pdbx_struct_sheet_hbond.range_1_auth_asym_id 
_pdbx_struct_sheet_hbond.range_1_auth_seq_id 
_pdbx_struct_sheet_hbond.range_2_label_atom_id 
_pdbx_struct_sheet_hbond.range_2_label_comp_id 
_pdbx_struct_sheet_hbond.range_2_label_asym_id 
_pdbx_struct_sheet_hbond.range_2_label_seq_id 
_pdbx_struct_sheet_hbond.range_2_PDB_ins_code 
_pdbx_struct_sheet_hbond.range_2_auth_atom_id 
_pdbx_struct_sheet_hbond.range_2_auth_comp_id 
_pdbx_struct_sheet_hbond.range_2_auth_asym_id 
_pdbx_struct_sheet_hbond.range_2_auth_seq_id 
AA1 1  2  N TRP A 782  ? N TRP A 793  O ALA A 795  ? O ALA A 806  
AA1 1  19 N TYR A 781  ? N TYR A 792  O PHE A 1118 ? O PHE A 1129 
AA1 2  3  N ALA A 804  ? N ALA A 815  O MET A 811  ? O MET A 822  
AA1 3  4  N ARG A 814  ? N ARG A 825  O ALA A 859  ? O ALA A 870  
AA1 4  5  N VAL A 860  ? N VAL A 871  O ILE A 871  ? O ILE A 882  
AA1 5  6  N SER A 868  ? N SER A 879  O SER A 888  ? O SER A 899  
AA1 6  7  N ILE A 893  ? N ILE A 904  O LEU A 896  ? O LEU A 907  
AA1 7  9  N GLY A 897  ? N GLY A 908  O SER A 941  ? O SER A 952  
AA1 8  9  N GLN A 917  ? N GLN A 928  O TRP A 928  ? O TRP A 939  
AA1 9  10 N LEU A 938  ? N LEU A 949  O LEU A 954  ? O LEU A 965  
AA1 9  11 N ARG A 932  ? N ARG A 943  O THR A 960  ? O THR A 971  
AA1 10 12 N SER A 953  ? N SER A 964  O MET A 973  ? O MET A 984  
AA1 12 13 N TRP A 972  ? N TRP A 983  O ILE A 996  ? O ILE A 1007 
AA1 13 14 N ASN A 993  ? N ASN A 1004 O ALA A 1023 ? O ALA A 1034 
AA1 13 15 N ARG A 987  ? N ARG A 998  O ARG A 1029 ? O ARG A 1040 
AA1 14 16 N VAL A 1026 ? N VAL A 1037 O ALA A 1041 ? O ALA A 1052 
AA1 15 16 N GLU A 1030 ? N GLU A 1041 O TRP A 1037 ? O TRP A 1048 
AA1 16 17 N SER A 1044 ? N SER A 1055 O GLY A 1084 ? O GLY A 1095 
AA1 17 18 N ARG A 1093 ? N ARG A 1104 O VAL A 1101 ? O VAL A 1112 
AA1 18 19 N ASP A 1106 ? N ASP A 1117 O HIS A 1117 ? O HIS A 1128 
AA2 1  2  N GLY A 838  ? N GLY A 849  O TYR A 1006 ? O TYR A 1017 
AA3 1  2  N MET A 1053 ? N MET A 1064 O ASN A 1075 ? O ASN A 1086 
# 
_pdbx_entry_details.entry_id                   9B8H 
_pdbx_entry_details.nonpolymer_details         ? 
_pdbx_entry_details.sequence_details           ? 
_pdbx_entry_details.compound_details           ? 
_pdbx_entry_details.source_details             ? 
_pdbx_entry_details.has_ligand_of_interest     Y 
_pdbx_entry_details.has_protein_modification   Y 
# 
loop_
_pdbx_validate_torsion.id 
_pdbx_validate_torsion.PDB_model_num 
_pdbx_validate_torsion.auth_comp_id 
_pdbx_validate_torsion.auth_asym_id 
_pdbx_validate_torsion.auth_seq_id 
_pdbx_validate_torsion.PDB_ins_code 
_pdbx_validate_torsion.label_alt_id 
_pdbx_validate_torsion.phi 
_pdbx_validate_torsion.psi 
1  1 SER A 602  ? ? 60.55   -130.99 
2  1 ARG A 617  ? ? 68.53   164.84  
3  1 TYR A 619  ? ? 71.26   -78.11  
4  1 PRO A 634  ? ? -90.82  52.26   
5  1 SER A 670  ? ? -38.10  137.54  
6  1 SER A 707  ? ? -161.84 -168.88 
7  1 TYR A 817  ? ? -160.10 116.55  
8  1 SER A 818  ? ? 57.87   -128.67 
9  1 ASN A 859  ? ? -105.52 64.92   
10 1 VAL A 877  ? ? -92.77  -61.64  
11 1 ALA A 958  ? ? -145.02 22.14   
12 1 LYS A 1122 ? ? 72.21   -6.00   
# 
_em_3d_fitting.id                1 
_em_3d_fitting.entry_id          9B8H 
_em_3d_fitting.method            ? 
_em_3d_fitting.target_criteria   ? 
_em_3d_fitting.details           ? 
_em_3d_fitting.overall_b_value   ? 
_em_3d_fitting.ref_space         ? 
_em_3d_fitting.ref_protocol      ? 
# 
_em_3d_reconstruction.entry_id                    9B8H 
_em_3d_reconstruction.id                          1 
_em_3d_reconstruction.method                      ? 
_em_3d_reconstruction.algorithm                   ? 
_em_3d_reconstruction.citation_id                 ? 
_em_3d_reconstruction.details                     ? 
_em_3d_reconstruction.resolution                  3.80 
_em_3d_reconstruction.resolution_method           'FSC 0.143 CUT-OFF' 
_em_3d_reconstruction.magnification_calibration   ? 
_em_3d_reconstruction.nominal_pixel_size          ? 
_em_3d_reconstruction.actual_pixel_size           ? 
_em_3d_reconstruction.num_particles               60119 
_em_3d_reconstruction.euler_angles_details        ? 
_em_3d_reconstruction.num_class_averages          ? 
_em_3d_reconstruction.refinement_type             ? 
_em_3d_reconstruction.image_processing_id         1 
_em_3d_reconstruction.symmetry_type               POINT 
# 
_em_buffer.id            1 
_em_buffer.specimen_id   1 
_em_buffer.name          ? 
_em_buffer.details       ? 
_em_buffer.pH            8.5 
# 
_em_entity_assembly.id                   1 
_em_entity_assembly.parent_id            0 
_em_entity_assembly.source               RECOMBINANT 
_em_entity_assembly.type                 COMPLEX 
_em_entity_assembly.name                 'Bacterial cellulose synthase subunit C in nanodisc with cellotetraose' 
_em_entity_assembly.details              
;Protein:
Bacterial cellulose synthase subunit C (BcsC)
Ligand: Cellotetraose
;
_em_entity_assembly.synonym              ? 
_em_entity_assembly.oligomeric_details   ? 
_em_entity_assembly.entity_id_list       1 
# 
_em_imaging.entry_id                        9B8H 
_em_imaging.id                              1 
_em_imaging.astigmatism                     ? 
_em_imaging.electron_beam_tilt_params       ? 
_em_imaging.residual_tilt                   ? 
_em_imaging.microscope_model                'FEI TITAN KRIOS' 
_em_imaging.specimen_holder_type            ? 
_em_imaging.specimen_holder_model           ? 
_em_imaging.details                         ? 
_em_imaging.date                            ? 
_em_imaging.accelerating_voltage            300 
_em_imaging.illumination_mode               'FLOOD BEAM' 
_em_imaging.mode                            'BRIGHT FIELD' 
_em_imaging.nominal_cs                      ? 
_em_imaging.nominal_defocus_min             1200 
_em_imaging.nominal_defocus_max             2400 
_em_imaging.calibrated_defocus_min          ? 
_em_imaging.calibrated_defocus_max          ? 
_em_imaging.tilt_angle_min                  ? 
_em_imaging.tilt_angle_max                  ? 
_em_imaging.nominal_magnification           ? 
_em_imaging.calibrated_magnification        ? 
_em_imaging.electron_source                 'FIELD EMISSION GUN' 
_em_imaging.citation_id                     ? 
_em_imaging.temperature                     ? 
_em_imaging.detector_distance               ? 
_em_imaging.recording_temperature_minimum   ? 
_em_imaging.recording_temperature_maximum   ? 
_em_imaging.alignment_procedure             ? 
_em_imaging.c2_aperture_diameter            ? 
_em_imaging.specimen_id                     1 
_em_imaging.cryogen                         ? 
# 
_em_vitrification.entry_id              9B8H 
_em_vitrification.id                    1 
_em_vitrification.specimen_id           1 
_em_vitrification.cryogen_name          ETHANE 
_em_vitrification.humidity              ? 
_em_vitrification.temp                  ? 
_em_vitrification.chamber_temperature   ? 
_em_vitrification.instrument            ? 
_em_vitrification.method                ? 
_em_vitrification.time_resolved_state   ? 
_em_vitrification.citation_id           ? 
_em_vitrification.details               ? 
# 
_em_experiment.entry_id                9B8H 
_em_experiment.id                      1 
_em_experiment.reconstruction_method   'SINGLE PARTICLE' 
_em_experiment.aggregation_state       PARTICLE 
_em_experiment.entity_assembly_id      1 
# 
loop_
_pdbx_unobs_or_zero_occ_residues.id 
_pdbx_unobs_or_zero_occ_residues.PDB_model_num 
_pdbx_unobs_or_zero_occ_residues.polymer_flag 
_pdbx_unobs_or_zero_occ_residues.occupancy_flag 
_pdbx_unobs_or_zero_occ_residues.auth_asym_id 
_pdbx_unobs_or_zero_occ_residues.auth_comp_id 
_pdbx_unobs_or_zero_occ_residues.auth_seq_id 
_pdbx_unobs_or_zero_occ_residues.PDB_ins_code 
_pdbx_unobs_or_zero_occ_residues.label_asym_id 
_pdbx_unobs_or_zero_occ_residues.label_comp_id 
_pdbx_unobs_or_zero_occ_residues.label_seq_id 
1   1 Y 1 A MET 12  ? A MET 1   
2   1 Y 1 A HIS 13  ? A HIS 2   
3   1 Y 1 A HIS 14  ? A HIS 3   
4   1 Y 1 A HIS 15  ? A HIS 4   
5   1 Y 1 A HIS 16  ? A HIS 5   
6   1 Y 1 A HIS 17  ? A HIS 6   
7   1 Y 1 A HIS 18  ? A HIS 7   
8   1 Y 1 A HIS 19  ? A HIS 8   
9   1 Y 1 A HIS 20  ? A HIS 9   
10  1 Y 1 A VAL 21  ? A VAL 10  
11  1 Y 1 A GLU 22  ? A GLU 11  
12  1 Y 1 A ALA 23  ? A ALA 12  
13  1 Y 1 A ALA 24  ? A ALA 13  
14  1 Y 1 A PRO 25  ? A PRO 14  
15  1 Y 1 A THR 26  ? A THR 15  
16  1 Y 1 A ALA 27  ? A ALA 16  
17  1 Y 1 A GLN 28  ? A GLN 17  
18  1 Y 1 A GLN 29  ? A GLN 18  
19  1 Y 1 A GLN 30  ? A GLN 19  
20  1 Y 1 A LEU 31  ? A LEU 20  
21  1 Y 1 A LEU 32  ? A LEU 21  
22  1 Y 1 A GLU 33  ? A GLU 22  
23  1 Y 1 A GLN 34  ? A GLN 23  
24  1 Y 1 A VAL 35  ? A VAL 24  
25  1 Y 1 A ARG 36  ? A ARG 25  
26  1 Y 1 A LEU 37  ? A LEU 26  
27  1 Y 1 A GLY 38  ? A GLY 27  
28  1 Y 1 A GLU 39  ? A GLU 28  
29  1 Y 1 A ALA 40  ? A ALA 29  
30  1 Y 1 A THR 41  ? A THR 30  
31  1 Y 1 A HIS 42  ? A HIS 31  
32  1 Y 1 A ARG 43  ? A ARG 32  
33  1 Y 1 A GLU 44  ? A GLU 33  
34  1 Y 1 A ASP 45  ? A ASP 34  
35  1 Y 1 A LEU 46  ? A LEU 35  
36  1 Y 1 A VAL 47  ? A VAL 36  
37  1 Y 1 A GLN 48  ? A GLN 37  
38  1 Y 1 A GLN 49  ? A GLN 38  
39  1 Y 1 A SER 50  ? A SER 39  
40  1 Y 1 A LEU 51  ? A LEU 40  
41  1 Y 1 A TYR 52  ? A TYR 41  
42  1 Y 1 A ARG 53  ? A ARG 42  
43  1 Y 1 A LEU 54  ? A LEU 43  
44  1 Y 1 A GLU 55  ? A GLU 44  
45  1 Y 1 A LEU 56  ? A LEU 45  
46  1 Y 1 A ILE 57  ? A ILE 46  
47  1 Y 1 A ASP 58  ? A ASP 47  
48  1 Y 1 A PRO 59  ? A PRO 48  
49  1 Y 1 A ASN 60  ? A ASN 49  
50  1 Y 1 A ASN 61  ? A ASN 50  
51  1 Y 1 A PRO 62  ? A PRO 51  
52  1 Y 1 A ASP 63  ? A ASP 52  
53  1 Y 1 A VAL 64  ? A VAL 53  
54  1 Y 1 A VAL 65  ? A VAL 54  
55  1 Y 1 A ALA 66  ? A ALA 55  
56  1 Y 1 A ALA 67  ? A ALA 56  
57  1 Y 1 A ARG 68  ? A ARG 57  
58  1 Y 1 A PHE 69  ? A PHE 58  
59  1 Y 1 A ARG 70  ? A ARG 59  
60  1 Y 1 A SER 71  ? A SER 60  
61  1 Y 1 A LEU 72  ? A LEU 61  
62  1 Y 1 A LEU 73  ? A LEU 62  
63  1 Y 1 A ARG 74  ? A ARG 63  
64  1 Y 1 A GLN 75  ? A GLN 64  
65  1 Y 1 A GLY 76  ? A GLY 65  
66  1 Y 1 A ASP 77  ? A ASP 66  
67  1 Y 1 A ILE 78  ? A ILE 67  
68  1 Y 1 A ASP 79  ? A ASP 68  
69  1 Y 1 A GLY 80  ? A GLY 69  
70  1 Y 1 A ALA 81  ? A ALA 70  
71  1 Y 1 A GLN 82  ? A GLN 71  
72  1 Y 1 A LYS 83  ? A LYS 72  
73  1 Y 1 A GLN 84  ? A GLN 73  
74  1 Y 1 A LEU 85  ? A LEU 74  
75  1 Y 1 A ASP 86  ? A ASP 75  
76  1 Y 1 A ARG 87  ? A ARG 76  
77  1 Y 1 A LEU 88  ? A LEU 77  
78  1 Y 1 A SER 89  ? A SER 78  
79  1 Y 1 A GLN 90  ? A GLN 79  
80  1 Y 1 A LEU 91  ? A LEU 80  
81  1 Y 1 A ALA 92  ? A ALA 81  
82  1 Y 1 A PRO 93  ? A PRO 82  
83  1 Y 1 A SER 94  ? A SER 83  
84  1 Y 1 A SER 95  ? A SER 84  
85  1 Y 1 A ASN 96  ? A ASN 85  
86  1 Y 1 A ALA 97  ? A ALA 86  
87  1 Y 1 A TYR 98  ? A TYR 87  
88  1 Y 1 A LYS 99  ? A LYS 88  
89  1 Y 1 A SER 100 ? A SER 89  
90  1 Y 1 A SER 101 ? A SER 90  
91  1 Y 1 A ARG 102 ? A ARG 91  
92  1 Y 1 A THR 103 ? A THR 92  
93  1 Y 1 A THR 104 ? A THR 93  
94  1 Y 1 A MET 105 ? A MET 94  
95  1 Y 1 A LEU 106 ? A LEU 95  
96  1 Y 1 A LEU 107 ? A LEU 96  
97  1 Y 1 A SER 108 ? A SER 97  
98  1 Y 1 A THR 109 ? A THR 98  
99  1 Y 1 A PRO 110 ? A PRO 99  
100 1 Y 1 A ASP 111 ? A ASP 100 
101 1 Y 1 A GLY 112 ? A GLY 101 
102 1 Y 1 A ARG 113 ? A ARG 102 
103 1 Y 1 A GLN 114 ? A GLN 103 
104 1 Y 1 A ALA 115 ? A ALA 104 
105 1 Y 1 A LEU 116 ? A LEU 105 
106 1 Y 1 A GLN 117 ? A GLN 106 
107 1 Y 1 A GLN 118 ? A GLN 107 
108 1 Y 1 A ALA 119 ? A ALA 108 
109 1 Y 1 A ARG 120 ? A ARG 109 
110 1 Y 1 A LEU 121 ? A LEU 110 
111 1 Y 1 A GLN 122 ? A GLN 111 
112 1 Y 1 A ALA 123 ? A ALA 112 
113 1 Y 1 A THR 124 ? A THR 113 
114 1 Y 1 A THR 125 ? A THR 114 
115 1 Y 1 A GLY 126 ? A GLY 115 
116 1 Y 1 A HIS 127 ? A HIS 116 
117 1 Y 1 A ALA 128 ? A ALA 117 
118 1 Y 1 A GLU 129 ? A GLU 118 
119 1 Y 1 A GLU 130 ? A GLU 119 
120 1 Y 1 A ALA 131 ? A ALA 120 
121 1 Y 1 A VAL 132 ? A VAL 121 
122 1 Y 1 A ALA 133 ? A ALA 122 
123 1 Y 1 A SER 134 ? A SER 123 
124 1 Y 1 A TYR 135 ? A TYR 124 
125 1 Y 1 A ASN 136 ? A ASN 125 
126 1 Y 1 A LYS 137 ? A LYS 126 
127 1 Y 1 A LEU 138 ? A LEU 127 
128 1 Y 1 A PHE 139 ? A PHE 128 
129 1 Y 1 A ASN 140 ? A ASN 129 
130 1 Y 1 A GLY 141 ? A GLY 130 
131 1 Y 1 A ALA 142 ? A ALA 131 
132 1 Y 1 A PRO 143 ? A PRO 132 
133 1 Y 1 A PRO 144 ? A PRO 133 
134 1 Y 1 A GLU 145 ? A GLU 134 
135 1 Y 1 A GLY 146 ? A GLY 135 
136 1 Y 1 A ASP 147 ? A ASP 136 
137 1 Y 1 A ILE 148 ? A ILE 137 
138 1 Y 1 A ALA 149 ? A ALA 138 
139 1 Y 1 A VAL 150 ? A VAL 139 
140 1 Y 1 A GLU 151 ? A GLU 140 
141 1 Y 1 A TYR 152 ? A TYR 141 
142 1 Y 1 A TRP 153 ? A TRP 142 
143 1 Y 1 A SER 154 ? A SER 143 
144 1 Y 1 A THR 155 ? A THR 144 
145 1 Y 1 A VAL 156 ? A VAL 145 
146 1 Y 1 A ALA 157 ? A ALA 146 
147 1 Y 1 A LYS 158 ? A LYS 147 
148 1 Y 1 A ILE 159 ? A ILE 148 
149 1 Y 1 A PRO 160 ? A PRO 149 
150 1 Y 1 A ALA 161 ? A ALA 150 
151 1 Y 1 A ARG 162 ? A ARG 151 
152 1 Y 1 A ARG 163 ? A ARG 152 
153 1 Y 1 A GLY 164 ? A GLY 153 
154 1 Y 1 A GLU 165 ? A GLU 154 
155 1 Y 1 A ALA 166 ? A ALA 155 
156 1 Y 1 A ILE 167 ? A ILE 156 
157 1 Y 1 A ASN 168 ? A ASN 157 
158 1 Y 1 A GLN 169 ? A GLN 158 
159 1 Y 1 A LEU 170 ? A LEU 159 
160 1 Y 1 A LYS 171 ? A LYS 160 
161 1 Y 1 A ARG 172 ? A ARG 161 
162 1 Y 1 A ILE 173 ? A ILE 162 
163 1 Y 1 A ASN 174 ? A ASN 163 
164 1 Y 1 A ALA 175 ? A ALA 164 
165 1 Y 1 A ASP 176 ? A ASP 165 
166 1 Y 1 A ALA 177 ? A ALA 166 
167 1 Y 1 A PRO 178 ? A PRO 167 
168 1 Y 1 A GLY 179 ? A GLY 168 
169 1 Y 1 A ASN 180 ? A ASN 169 
170 1 Y 1 A THR 181 ? A THR 170 
171 1 Y 1 A GLY 182 ? A GLY 171 
172 1 Y 1 A LEU 183 ? A LEU 172 
173 1 Y 1 A GLN 184 ? A GLN 173 
174 1 Y 1 A ASN 185 ? A ASN 174 
175 1 Y 1 A ASN 186 ? A ASN 175 
176 1 Y 1 A LEU 187 ? A LEU 176 
177 1 Y 1 A ALA 188 ? A ALA 177 
178 1 Y 1 A LEU 189 ? A LEU 178 
179 1 Y 1 A LEU 190 ? A LEU 179 
180 1 Y 1 A LEU 191 ? A LEU 180 
181 1 Y 1 A PHE 192 ? A PHE 181 
182 1 Y 1 A SER 193 ? A SER 182 
183 1 Y 1 A SER 194 ? A SER 183 
184 1 Y 1 A ASP 195 ? A ASP 184 
185 1 Y 1 A ARG 196 ? A ARG 185 
186 1 Y 1 A ARG 197 ? A ARG 186 
187 1 Y 1 A ASP 198 ? A ASP 187 
188 1 Y 1 A GLU 199 ? A GLU 188 
189 1 Y 1 A GLY 200 ? A GLY 189 
190 1 Y 1 A PHE 201 ? A PHE 190 
191 1 Y 1 A ALA 202 ? A ALA 191 
192 1 Y 1 A VAL 203 ? A VAL 192 
193 1 Y 1 A LEU 204 ? A LEU 193 
194 1 Y 1 A GLU 205 ? A GLU 194 
195 1 Y 1 A GLN 206 ? A GLN 195 
196 1 Y 1 A MET 207 ? A MET 196 
197 1 Y 1 A ALA 208 ? A ALA 197 
198 1 Y 1 A LYS 209 ? A LYS 198 
199 1 Y 1 A SER 210 ? A SER 199 
200 1 Y 1 A ASN 211 ? A ASN 200 
201 1 Y 1 A ALA 212 ? A ALA 201 
202 1 Y 1 A GLY 213 ? A GLY 202 
203 1 Y 1 A ARG 214 ? A ARG 203 
204 1 Y 1 A GLU 215 ? A GLU 204 
205 1 Y 1 A GLY 216 ? A GLY 205 
206 1 Y 1 A ALA 217 ? A ALA 206 
207 1 Y 1 A SER 218 ? A SER 207 
208 1 Y 1 A LYS 219 ? A LYS 208 
209 1 Y 1 A ILE 220 ? A ILE 209 
210 1 Y 1 A TRP 221 ? A TRP 210 
211 1 Y 1 A TYR 222 ? A TYR 211 
212 1 Y 1 A GLY 223 ? A GLY 212 
213 1 Y 1 A GLN 224 ? A GLN 213 
214 1 Y 1 A ILE 225 ? A ILE 214 
215 1 Y 1 A LYS 226 ? A LYS 215 
216 1 Y 1 A ASP 227 ? A ASP 216 
217 1 Y 1 A MET 228 ? A MET 217 
218 1 Y 1 A PRO 229 ? A PRO 218 
219 1 Y 1 A VAL 230 ? A VAL 219 
220 1 Y 1 A SER 231 ? A SER 220 
221 1 Y 1 A ASP 232 ? A ASP 221 
222 1 Y 1 A ALA 233 ? A ALA 222 
223 1 Y 1 A SER 234 ? A SER 223 
224 1 Y 1 A VAL 235 ? A VAL 224 
225 1 Y 1 A SER 236 ? A SER 225 
226 1 Y 1 A ALA 237 ? A ALA 226 
227 1 Y 1 A LEU 238 ? A LEU 227 
228 1 Y 1 A LYS 239 ? A LYS 228 
229 1 Y 1 A LYS 240 ? A LYS 229 
230 1 Y 1 A TYR 241 ? A TYR 230 
231 1 Y 1 A LEU 242 ? A LEU 231 
232 1 Y 1 A SER 243 ? A SER 232 
233 1 Y 1 A ILE 244 ? A ILE 233 
234 1 Y 1 A PHE 245 ? A PHE 234 
235 1 Y 1 A SER 246 ? A SER 235 
236 1 Y 1 A ASP 247 ? A ASP 236 
237 1 Y 1 A GLY 248 ? A GLY 237 
238 1 Y 1 A ASP 249 ? A ASP 238 
239 1 Y 1 A SER 250 ? A SER 239 
240 1 Y 1 A VAL 251 ? A VAL 240 
241 1 Y 1 A ALA 252 ? A ALA 241 
242 1 Y 1 A ALA 253 ? A ALA 242 
243 1 Y 1 A ALA 254 ? A ALA 243 
244 1 Y 1 A GLN 255 ? A GLN 244 
245 1 Y 1 A SER 256 ? A SER 245 
246 1 Y 1 A GLN 257 ? A GLN 246 
247 1 Y 1 A LEU 258 ? A LEU 247 
248 1 Y 1 A ALA 259 ? A ALA 248 
249 1 Y 1 A GLU 260 ? A GLU 249 
250 1 Y 1 A GLN 261 ? A GLN 250 
251 1 Y 1 A GLN 262 ? A GLN 251 
252 1 Y 1 A LYS 263 ? A LYS 252 
253 1 Y 1 A GLN 264 ? A GLN 253 
254 1 Y 1 A LEU 265 ? A LEU 254 
255 1 Y 1 A ALA 266 ? A ALA 255 
256 1 Y 1 A ASP 267 ? A ASP 256 
257 1 Y 1 A PRO 268 ? A PRO 257 
258 1 Y 1 A ALA 269 ? A ALA 258 
259 1 Y 1 A PHE 270 ? A PHE 259 
260 1 Y 1 A ARG 271 ? A ARG 260 
261 1 Y 1 A ALA 272 ? A ALA 261 
262 1 Y 1 A ARG 273 ? A ARG 262 
263 1 Y 1 A ALA 274 ? A ALA 263 
264 1 Y 1 A GLN 275 ? A GLN 264 
265 1 Y 1 A GLY 276 ? A GLY 265 
266 1 Y 1 A LEU 277 ? A LEU 266 
267 1 Y 1 A ALA 278 ? A ALA 267 
268 1 Y 1 A ALA 279 ? A ALA 268 
269 1 Y 1 A VAL 280 ? A VAL 269 
270 1 Y 1 A ASP 281 ? A ASP 270 
271 1 Y 1 A SER 282 ? A SER 271 
272 1 Y 1 A GLY 283 ? A GLY 272 
273 1 Y 1 A MET 284 ? A MET 273 
274 1 Y 1 A ALA 285 ? A ALA 274 
275 1 Y 1 A GLY 286 ? A GLY 275 
276 1 Y 1 A LYS 287 ? A LYS 276 
277 1 Y 1 A ALA 288 ? A ALA 277 
278 1 Y 1 A ILE 289 ? A ILE 278 
279 1 Y 1 A PRO 290 ? A PRO 279 
280 1 Y 1 A GLU 291 ? A GLU 280 
281 1 Y 1 A LEU 292 ? A LEU 281 
282 1 Y 1 A GLN 293 ? A GLN 282 
283 1 Y 1 A GLN 294 ? A GLN 283 
284 1 Y 1 A ALA 295 ? A ALA 284 
285 1 Y 1 A VAL 296 ? A VAL 285 
286 1 Y 1 A ARG 297 ? A ARG 286 
287 1 Y 1 A ALA 298 ? A ALA 287 
288 1 Y 1 A ASN 299 ? A ASN 288 
289 1 Y 1 A PRO 300 ? A PRO 289 
290 1 Y 1 A LYS 301 ? A LYS 290 
291 1 Y 1 A ASP 302 ? A ASP 291 
292 1 Y 1 A SER 303 ? A SER 292 
293 1 Y 1 A GLU 304 ? A GLU 293 
294 1 Y 1 A ALA 305 ? A ALA 294 
295 1 Y 1 A LEU 306 ? A LEU 295 
296 1 Y 1 A GLY 307 ? A GLY 296 
297 1 Y 1 A ALA 308 ? A ALA 297 
298 1 Y 1 A LEU 309 ? A LEU 298 
299 1 Y 1 A GLY 310 ? A GLY 299 
300 1 Y 1 A GLN 311 ? A GLN 300 
301 1 Y 1 A ALA 312 ? A ALA 301 
302 1 Y 1 A TYR 313 ? A TYR 302 
303 1 Y 1 A SER 314 ? A SER 303 
304 1 Y 1 A GLN 315 ? A GLN 304 
305 1 Y 1 A LYS 316 ? A LYS 305 
306 1 Y 1 A GLY 317 ? A GLY 306 
307 1 Y 1 A ASP 318 ? A ASP 307 
308 1 Y 1 A ARG 319 ? A ARG 308 
309 1 Y 1 A ALA 320 ? A ALA 309 
310 1 Y 1 A ASN 321 ? A ASN 310 
311 1 Y 1 A ALA 322 ? A ALA 311 
312 1 Y 1 A VAL 323 ? A VAL 312 
313 1 Y 1 A ALA 324 ? A ALA 313 
314 1 Y 1 A ASN 325 ? A ASN 314 
315 1 Y 1 A LEU 326 ? A LEU 315 
316 1 Y 1 A GLU 327 ? A GLU 316 
317 1 Y 1 A LYS 328 ? A LYS 317 
318 1 Y 1 A ALA 329 ? A ALA 318 
319 1 Y 1 A LEU 330 ? A LEU 319 
320 1 Y 1 A ALA 331 ? A ALA 320 
321 1 Y 1 A LEU 332 ? A LEU 321 
322 1 Y 1 A ASP 333 ? A ASP 322 
323 1 Y 1 A PRO 334 ? A PRO 323 
324 1 Y 1 A HIS 335 ? A HIS 324 
325 1 Y 1 A SER 336 ? A SER 325 
326 1 Y 1 A SER 337 ? A SER 326 
327 1 Y 1 A ASN 338 ? A ASN 327 
328 1 Y 1 A ASN 339 ? A ASN 328 
329 1 Y 1 A ASP 340 ? A ASP 329 
330 1 Y 1 A LYS 341 ? A LYS 330 
331 1 Y 1 A TRP 342 ? A TRP 331 
332 1 Y 1 A ASN 343 ? A ASN 332 
333 1 Y 1 A SER 344 ? A SER 333 
334 1 Y 1 A LEU 345 ? A LEU 334 
335 1 Y 1 A LEU 346 ? A LEU 335 
336 1 Y 1 A LYS 347 ? A LYS 336 
337 1 Y 1 A VAL 348 ? A VAL 337 
338 1 Y 1 A ASN 349 ? A ASN 338 
339 1 Y 1 A ARG 350 ? A ARG 339 
340 1 Y 1 A TYR 351 ? A TYR 340 
341 1 Y 1 A TRP 352 ? A TRP 341 
342 1 Y 1 A LEU 353 ? A LEU 342 
343 1 Y 1 A ALA 354 ? A ALA 343 
344 1 Y 1 A ILE 355 ? A ILE 344 
345 1 Y 1 A GLN 356 ? A GLN 345 
346 1 Y 1 A GLN 357 ? A GLN 346 
347 1 Y 1 A GLY 358 ? A GLY 347 
348 1 Y 1 A ASP 359 ? A ASP 348 
349 1 Y 1 A ALA 360 ? A ALA 349 
350 1 Y 1 A ALA 361 ? A ALA 350 
351 1 Y 1 A LEU 362 ? A LEU 351 
352 1 Y 1 A LYS 363 ? A LYS 352 
353 1 Y 1 A ALA 364 ? A ALA 353 
354 1 Y 1 A ASN 365 ? A ASN 354 
355 1 Y 1 A ASN 366 ? A ASN 355 
356 1 Y 1 A PRO 367 ? A PRO 356 
357 1 Y 1 A ASP 368 ? A ASP 357 
358 1 Y 1 A ARG 369 ? A ARG 358 
359 1 Y 1 A ALA 370 ? A ALA 359 
360 1 Y 1 A GLU 371 ? A GLU 360 
361 1 Y 1 A ARG 372 ? A ARG 361 
362 1 Y 1 A LEU 373 ? A LEU 362 
363 1 Y 1 A PHE 374 ? A PHE 363 
364 1 Y 1 A GLN 375 ? A GLN 364 
365 1 Y 1 A GLN 376 ? A GLN 365 
366 1 Y 1 A ALA 377 ? A ALA 366 
367 1 Y 1 A ARG 378 ? A ARG 367 
368 1 Y 1 A ASN 379 ? A ASN 368 
369 1 Y 1 A VAL 380 ? A VAL 369 
370 1 Y 1 A ASP 381 ? A ASP 370 
371 1 Y 1 A ASN 382 ? A ASN 371 
372 1 Y 1 A THR 383 ? A THR 372 
373 1 Y 1 A ASP 384 ? A ASP 373 
374 1 Y 1 A SER 385 ? A SER 374 
375 1 Y 1 A TYR 386 ? A TYR 375 
376 1 Y 1 A ALA 387 ? A ALA 376 
377 1 Y 1 A VAL 388 ? A VAL 377 
378 1 Y 1 A LEU 389 ? A LEU 378 
379 1 Y 1 A GLY 390 ? A GLY 379 
380 1 Y 1 A LEU 391 ? A LEU 380 
381 1 Y 1 A GLY 392 ? A GLY 381 
382 1 Y 1 A ASP 393 ? A ASP 382 
383 1 Y 1 A VAL 394 ? A VAL 383 
384 1 Y 1 A ALA 395 ? A ALA 384 
385 1 Y 1 A MET 396 ? A MET 385 
386 1 Y 1 A ALA 397 ? A ALA 386 
387 1 Y 1 A ARG 398 ? A ARG 387 
388 1 Y 1 A LYS 399 ? A LYS 388 
389 1 Y 1 A ASP 400 ? A ASP 389 
390 1 Y 1 A TYR 401 ? A TYR 390 
391 1 Y 1 A PRO 402 ? A PRO 391 
392 1 Y 1 A ALA 403 ? A ALA 392 
393 1 Y 1 A ALA 404 ? A ALA 393 
394 1 Y 1 A GLU 405 ? A GLU 394 
395 1 Y 1 A ARG 406 ? A ARG 395 
396 1 Y 1 A TYR 407 ? A TYR 396 
397 1 Y 1 A TYR 408 ? A TYR 397 
398 1 Y 1 A GLN 409 ? A GLN 398 
399 1 Y 1 A GLN 410 ? A GLN 399 
400 1 Y 1 A THR 411 ? A THR 400 
401 1 Y 1 A LEU 412 ? A LEU 401 
402 1 Y 1 A ARG 413 ? A ARG 402 
403 1 Y 1 A MET 414 ? A MET 403 
404 1 Y 1 A ASP 415 ? A ASP 404 
405 1 Y 1 A SER 416 ? A SER 405 
406 1 Y 1 A GLY 417 ? A GLY 406 
407 1 Y 1 A ASN 418 ? A ASN 407 
408 1 Y 1 A THR 419 ? A THR 408 
409 1 Y 1 A ASN 420 ? A ASN 409 
410 1 Y 1 A ALA 421 ? A ALA 410 
411 1 Y 1 A VAL 422 ? A VAL 411 
412 1 Y 1 A ARG 423 ? A ARG 412 
413 1 Y 1 A GLY 424 ? A GLY 413 
414 1 Y 1 A LEU 425 ? A LEU 414 
415 1 Y 1 A ALA 426 ? A ALA 415 
416 1 Y 1 A ASN 427 ? A ASN 416 
417 1 Y 1 A ILE 428 ? A ILE 417 
418 1 Y 1 A TYR 429 ? A TYR 418 
419 1 Y 1 A ARG 430 ? A ARG 419 
420 1 Y 1 A GLN 431 ? A GLN 420 
421 1 Y 1 A GLN 432 ? A GLN 421 
422 1 Y 1 A SER 433 ? A SER 422 
423 1 Y 1 A PRO 434 ? A PRO 423 
424 1 Y 1 A GLU 435 ? A GLU 424 
425 1 Y 1 A LYS 436 ? A LYS 425 
426 1 Y 1 A ALA 437 ? A ALA 426 
427 1 Y 1 A GLU 438 ? A GLU 427 
428 1 Y 1 A ALA 439 ? A ALA 428 
429 1 Y 1 A PHE 440 ? A PHE 429 
430 1 Y 1 A ILE 441 ? A ILE 430 
431 1 Y 1 A ALA 442 ? A ALA 431 
432 1 Y 1 A SER 443 ? A SER 432 
433 1 Y 1 A LEU 444 ? A LEU 433 
434 1 Y 1 A SER 445 ? A SER 434 
435 1 Y 1 A ALA 446 ? A ALA 435 
436 1 Y 1 A SER 447 ? A SER 436 
437 1 Y 1 A GLN 448 ? A GLN 437 
438 1 Y 1 A ARG 449 ? A ARG 438 
439 1 Y 1 A ARG 450 ? A ARG 439 
440 1 Y 1 A SER 451 ? A SER 440 
441 1 Y 1 A ILE 452 ? A ILE 441 
442 1 Y 1 A ASP 453 ? A ASP 442 
443 1 Y 1 A ASP 454 ? A ASP 443 
444 1 Y 1 A ILE 455 ? A ILE 444 
445 1 Y 1 A GLU 456 ? A GLU 445 
446 1 Y 1 A ARG 457 ? A ARG 446 
447 1 Y 1 A SER 458 ? A SER 447 
448 1 Y 1 A LEU 459 ? A LEU 448 
449 1 Y 1 A GLN 460 ? A GLN 449 
450 1 Y 1 A ASN 461 ? A ASN 450 
451 1 Y 1 A ASP 462 ? A ASP 451 
452 1 Y 1 A ARG 463 ? A ARG 452 
453 1 Y 1 A LEU 464 ? A LEU 453 
454 1 Y 1 A ALA 465 ? A ALA 454 
455 1 Y 1 A GLN 466 ? A GLN 455 
456 1 Y 1 A GLN 467 ? A GLN 456 
457 1 Y 1 A ALA 468 ? A ALA 457 
458 1 Y 1 A GLU 469 ? A GLU 458 
459 1 Y 1 A ALA 470 ? A ALA 459 
460 1 Y 1 A LEU 471 ? A LEU 460 
461 1 Y 1 A GLU 472 ? A GLU 461 
462 1 Y 1 A ASN 473 ? A ASN 462 
463 1 Y 1 A GLN 474 ? A GLN 463 
464 1 Y 1 A GLY 475 ? A GLY 464 
465 1 Y 1 A LYS 476 ? A LYS 465 
466 1 Y 1 A TRP 477 ? A TRP 466 
467 1 Y 1 A ALA 478 ? A ALA 467 
468 1 Y 1 A GLN 479 ? A GLN 468 
469 1 Y 1 A ALA 480 ? A ALA 469 
470 1 Y 1 A ALA 481 ? A ALA 470 
471 1 Y 1 A ALA 482 ? A ALA 471 
472 1 Y 1 A LEU 483 ? A LEU 472 
473 1 Y 1 A GLN 484 ? A GLN 473 
474 1 Y 1 A ARG 485 ? A ARG 474 
475 1 Y 1 A GLN 486 ? A GLN 475 
476 1 Y 1 A ARG 487 ? A ARG 476 
477 1 Y 1 A LEU 488 ? A LEU 477 
478 1 Y 1 A ALA 489 ? A ALA 478 
479 1 Y 1 A LEU 490 ? A LEU 479 
480 1 Y 1 A ASP 491 ? A ASP 480 
481 1 Y 1 A PRO 492 ? A PRO 481 
482 1 Y 1 A GLY 493 ? A GLY 482 
483 1 Y 1 A SER 494 ? A SER 483 
484 1 Y 1 A VAL 495 ? A VAL 484 
485 1 Y 1 A TRP 496 ? A TRP 485 
486 1 Y 1 A ILE 497 ? A ILE 486 
487 1 Y 1 A THR 498 ? A THR 487 
488 1 Y 1 A TYR 499 ? A TYR 488 
489 1 Y 1 A ARG 500 ? A ARG 489 
490 1 Y 1 A LEU 501 ? A LEU 490 
491 1 Y 1 A SER 502 ? A SER 491 
492 1 Y 1 A GLN 503 ? A GLN 492 
493 1 Y 1 A ASP 504 ? A ASP 493 
494 1 Y 1 A LEU 505 ? A LEU 494 
495 1 Y 1 A TRP 506 ? A TRP 495 
496 1 Y 1 A GLN 507 ? A GLN 496 
497 1 Y 1 A ALA 508 ? A ALA 497 
498 1 Y 1 A GLY 509 ? A GLY 498 
499 1 Y 1 A GLN 510 ? A GLN 499 
500 1 Y 1 A ARG 511 ? A ARG 500 
501 1 Y 1 A SER 512 ? A SER 501 
502 1 Y 1 A GLN 513 ? A GLN 502 
503 1 Y 1 A ALA 514 ? A ALA 503 
504 1 Y 1 A ASP 515 ? A ASP 504 
505 1 Y 1 A THR 516 ? A THR 505 
506 1 Y 1 A LEU 517 ? A LEU 506 
507 1 Y 1 A MET 518 ? A MET 507 
508 1 Y 1 A ARG 519 ? A ARG 508 
509 1 Y 1 A ASN 520 ? A ASN 509 
510 1 Y 1 A LEU 521 ? A LEU 510 
511 1 Y 1 A ALA 522 ? A ALA 511 
512 1 Y 1 A GLN 523 ? A GLN 512 
513 1 Y 1 A GLN 524 ? A GLN 513 
514 1 Y 1 A LYS 525 ? A LYS 514 
515 1 Y 1 A SER 526 ? A SER 515 
516 1 Y 1 A ASN 527 ? A ASN 516 
517 1 Y 1 A ASP 528 ? A ASP 517 
518 1 Y 1 A PRO 529 ? A PRO 518 
519 1 Y 1 A GLU 530 ? A GLU 519 
520 1 Y 1 A GLN 531 ? A GLN 520 
521 1 Y 1 A VAL 532 ? A VAL 521 
522 1 Y 1 A TYR 533 ? A TYR 522 
523 1 Y 1 A ALA 534 ? A ALA 523 
524 1 Y 1 A TYR 535 ? A TYR 524 
525 1 Y 1 A GLY 536 ? A GLY 525 
526 1 Y 1 A LEU 537 ? A LEU 526 
527 1 Y 1 A TYR 538 ? A TYR 527 
528 1 Y 1 A LEU 539 ? A LEU 528 
529 1 Y 1 A SER 540 ? A SER 529 
530 1 Y 1 A GLY 541 ? A GLY 530 
531 1 Y 1 A HIS 542 ? A HIS 531 
532 1 Y 1 A ASP 543 ? A ASP 532 
533 1 Y 1 A GLN 544 ? A GLN 533 
534 1 Y 1 A ASP 545 ? A ASP 534 
535 1 Y 1 A ARG 546 ? A ARG 535 
536 1 Y 1 A ALA 547 ? A ALA 536 
537 1 Y 1 A ALA 548 ? A ALA 537 
538 1 Y 1 A LEU 549 ? A LEU 538 
539 1 Y 1 A ALA 550 ? A ALA 539 
540 1 Y 1 A HIS 551 ? A HIS 540 
541 1 Y 1 A ILE 552 ? A ILE 541 
542 1 Y 1 A ASN 553 ? A ASN 542 
543 1 Y 1 A SER 554 ? A SER 543 
544 1 Y 1 A LEU 555 ? A LEU 544 
545 1 Y 1 A PRO 556 ? A PRO 545 
546 1 Y 1 A ARG 557 ? A ARG 546 
547 1 Y 1 A ALA 558 ? A ALA 547 
548 1 Y 1 A GLN 559 ? A GLN 548 
549 1 Y 1 A TRP 560 ? A TRP 549 
550 1 Y 1 A ASN 561 ? A ASN 550 
551 1 Y 1 A SER 562 ? A SER 551 
552 1 Y 1 A ASN 563 ? A ASN 552 
553 1 Y 1 A ILE 564 ? A ILE 553 
554 1 Y 1 A GLN 565 ? A GLN 554 
555 1 Y 1 A GLU 566 ? A GLU 555 
556 1 Y 1 A LEU 567 ? A LEU 556 
557 1 Y 1 A VAL 568 ? A VAL 557 
558 1 Y 1 A ASN 569 ? A ASN 558 
559 1 Y 1 A ARG 570 ? A ARG 559 
# 
loop_
_chem_comp_atom.comp_id 
_chem_comp_atom.atom_id 
_chem_comp_atom.type_symbol 
_chem_comp_atom.pdbx_aromatic_flag 
_chem_comp_atom.pdbx_stereo_config 
_chem_comp_atom.pdbx_ordinal 
ALA N    N N N 1   
ALA CA   C N S 2   
ALA C    C N N 3   
ALA O    O N N 4   
ALA CB   C N N 5   
ALA OXT  O N N 6   
ALA H    H N N 7   
ALA H2   H N N 8   
ALA HA   H N N 9   
ALA HB1  H N N 10  
ALA HB2  H N N 11  
ALA HB3  H N N 12  
ALA HXT  H N N 13  
ARG N    N N N 14  
ARG CA   C N S 15  
ARG C    C N N 16  
ARG O    O N N 17  
ARG CB   C N N 18  
ARG CG   C N N 19  
ARG CD   C N N 20  
ARG NE   N N N 21  
ARG CZ   C N N 22  
ARG NH1  N N N 23  
ARG NH2  N N N 24  
ARG OXT  O N N 25  
ARG H    H N N 26  
ARG H2   H N N 27  
ARG HA   H N N 28  
ARG HB2  H N N 29  
ARG HB3  H N N 30  
ARG HG2  H N N 31  
ARG HG3  H N N 32  
ARG HD2  H N N 33  
ARG HD3  H N N 34  
ARG HE   H N N 35  
ARG HH11 H N N 36  
ARG HH12 H N N 37  
ARG HH21 H N N 38  
ARG HH22 H N N 39  
ARG HXT  H N N 40  
ASN N    N N N 41  
ASN CA   C N S 42  
ASN C    C N N 43  
ASN O    O N N 44  
ASN CB   C N N 45  
ASN CG   C N N 46  
ASN OD1  O N N 47  
ASN ND2  N N N 48  
ASN OXT  O N N 49  
ASN H    H N N 50  
ASN H2   H N N 51  
ASN HA   H N N 52  
ASN HB2  H N N 53  
ASN HB3  H N N 54  
ASN HD21 H N N 55  
ASN HD22 H N N 56  
ASN HXT  H N N 57  
ASP N    N N N 58  
ASP CA   C N S 59  
ASP C    C N N 60  
ASP O    O N N 61  
ASP CB   C N N 62  
ASP CG   C N N 63  
ASP OD1  O N N 64  
ASP OD2  O N N 65  
ASP OXT  O N N 66  
ASP H    H N N 67  
ASP H2   H N N 68  
ASP HA   H N N 69  
ASP HB2  H N N 70  
ASP HB3  H N N 71  
ASP HD2  H N N 72  
ASP HXT  H N N 73  
BGC C2   C N R 74  
BGC C3   C N S 75  
BGC C4   C N S 76  
BGC C5   C N R 77  
BGC C6   C N N 78  
BGC C1   C N R 79  
BGC O1   O N N 80  
BGC O2   O N N 81  
BGC O3   O N N 82  
BGC O4   O N N 83  
BGC O5   O N N 84  
BGC O6   O N N 85  
BGC H2   H N N 86  
BGC H3   H N N 87  
BGC H4   H N N 88  
BGC H5   H N N 89  
BGC H61  H N N 90  
BGC H62  H N N 91  
BGC H1   H N N 92  
BGC HO1  H N N 93  
BGC HO2  H N N 94  
BGC HO3  H N N 95  
BGC HO4  H N N 96  
BGC HO6  H N N 97  
CYS N    N N N 98  
CYS CA   C N R 99  
CYS C    C N N 100 
CYS O    O N N 101 
CYS CB   C N N 102 
CYS SG   S N N 103 
CYS OXT  O N N 104 
CYS H    H N N 105 
CYS H2   H N N 106 
CYS HA   H N N 107 
CYS HB2  H N N 108 
CYS HB3  H N N 109 
CYS HG   H N N 110 
CYS HXT  H N N 111 
GLN N    N N N 112 
GLN CA   C N S 113 
GLN C    C N N 114 
GLN O    O N N 115 
GLN CB   C N N 116 
GLN CG   C N N 117 
GLN CD   C N N 118 
GLN OE1  O N N 119 
GLN NE2  N N N 120 
GLN OXT  O N N 121 
GLN H    H N N 122 
GLN H2   H N N 123 
GLN HA   H N N 124 
GLN HB2  H N N 125 
GLN HB3  H N N 126 
GLN HG2  H N N 127 
GLN HG3  H N N 128 
GLN HE21 H N N 129 
GLN HE22 H N N 130 
GLN HXT  H N N 131 
GLU N    N N N 132 
GLU CA   C N S 133 
GLU C    C N N 134 
GLU O    O N N 135 
GLU CB   C N N 136 
GLU CG   C N N 137 
GLU CD   C N N 138 
GLU OE1  O N N 139 
GLU OE2  O N N 140 
GLU OXT  O N N 141 
GLU H    H N N 142 
GLU H2   H N N 143 
GLU HA   H N N 144 
GLU HB2  H N N 145 
GLU HB3  H N N 146 
GLU HG2  H N N 147 
GLU HG3  H N N 148 
GLU HE2  H N N 149 
GLU HXT  H N N 150 
GLY N    N N N 151 
GLY CA   C N N 152 
GLY C    C N N 153 
GLY O    O N N 154 
GLY OXT  O N N 155 
GLY H    H N N 156 
GLY H2   H N N 157 
GLY HA2  H N N 158 
GLY HA3  H N N 159 
GLY HXT  H N N 160 
HIS N    N N N 161 
HIS CA   C N S 162 
HIS C    C N N 163 
HIS O    O N N 164 
HIS CB   C N N 165 
HIS CG   C Y N 166 
HIS ND1  N Y N 167 
HIS CD2  C Y N 168 
HIS CE1  C Y N 169 
HIS NE2  N Y N 170 
HIS OXT  O N N 171 
HIS H    H N N 172 
HIS H2   H N N 173 
HIS HA   H N N 174 
HIS HB2  H N N 175 
HIS HB3  H N N 176 
HIS HD1  H N N 177 
HIS HD2  H N N 178 
HIS HE1  H N N 179 
HIS HE2  H N N 180 
HIS HXT  H N N 181 
ILE N    N N N 182 
ILE CA   C N S 183 
ILE C    C N N 184 
ILE O    O N N 185 
ILE CB   C N S 186 
ILE CG1  C N N 187 
ILE CG2  C N N 188 
ILE CD1  C N N 189 
ILE OXT  O N N 190 
ILE H    H N N 191 
ILE H2   H N N 192 
ILE HA   H N N 193 
ILE HB   H N N 194 
ILE HG12 H N N 195 
ILE HG13 H N N 196 
ILE HG21 H N N 197 
ILE HG22 H N N 198 
ILE HG23 H N N 199 
ILE HD11 H N N 200 
ILE HD12 H N N 201 
ILE HD13 H N N 202 
ILE HXT  H N N 203 
LEU N    N N N 204 
LEU CA   C N S 205 
LEU C    C N N 206 
LEU O    O N N 207 
LEU CB   C N N 208 
LEU CG   C N N 209 
LEU CD1  C N N 210 
LEU CD2  C N N 211 
LEU OXT  O N N 212 
LEU H    H N N 213 
LEU H2   H N N 214 
LEU HA   H N N 215 
LEU HB2  H N N 216 
LEU HB3  H N N 217 
LEU HG   H N N 218 
LEU HD11 H N N 219 
LEU HD12 H N N 220 
LEU HD13 H N N 221 
LEU HD21 H N N 222 
LEU HD22 H N N 223 
LEU HD23 H N N 224 
LEU HXT  H N N 225 
LYS N    N N N 226 
LYS CA   C N S 227 
LYS C    C N N 228 
LYS O    O N N 229 
LYS CB   C N N 230 
LYS CG   C N N 231 
LYS CD   C N N 232 
LYS CE   C N N 233 
LYS NZ   N N N 234 
LYS OXT  O N N 235 
LYS H    H N N 236 
LYS H2   H N N 237 
LYS HA   H N N 238 
LYS HB2  H N N 239 
LYS HB3  H N N 240 
LYS HG2  H N N 241 
LYS HG3  H N N 242 
LYS HD2  H N N 243 
LYS HD3  H N N 244 
LYS HE2  H N N 245 
LYS HE3  H N N 246 
LYS HZ1  H N N 247 
LYS HZ2  H N N 248 
LYS HZ3  H N N 249 
LYS HXT  H N N 250 
MET N    N N N 251 
MET CA   C N S 252 
MET C    C N N 253 
MET O    O N N 254 
MET CB   C N N 255 
MET CG   C N N 256 
MET SD   S N N 257 
MET CE   C N N 258 
MET OXT  O N N 259 
MET H    H N N 260 
MET H2   H N N 261 
MET HA   H N N 262 
MET HB2  H N N 263 
MET HB3  H N N 264 
MET HG2  H N N 265 
MET HG3  H N N 266 
MET HE1  H N N 267 
MET HE2  H N N 268 
MET HE3  H N N 269 
MET HXT  H N N 270 
PHE N    N N N 271 
PHE CA   C N S 272 
PHE C    C N N 273 
PHE O    O N N 274 
PHE CB   C N N 275 
PHE CG   C Y N 276 
PHE CD1  C Y N 277 
PHE CD2  C Y N 278 
PHE CE1  C Y N 279 
PHE CE2  C Y N 280 
PHE CZ   C Y N 281 
PHE OXT  O N N 282 
PHE H    H N N 283 
PHE H2   H N N 284 
PHE HA   H N N 285 
PHE HB2  H N N 286 
PHE HB3  H N N 287 
PHE HD1  H N N 288 
PHE HD2  H N N 289 
PHE HE1  H N N 290 
PHE HE2  H N N 291 
PHE HZ   H N N 292 
PHE HXT  H N N 293 
PRO N    N N N 294 
PRO CA   C N S 295 
PRO C    C N N 296 
PRO O    O N N 297 
PRO CB   C N N 298 
PRO CG   C N N 299 
PRO CD   C N N 300 
PRO OXT  O N N 301 
PRO H    H N N 302 
PRO HA   H N N 303 
PRO HB2  H N N 304 
PRO HB3  H N N 305 
PRO HG2  H N N 306 
PRO HG3  H N N 307 
PRO HD2  H N N 308 
PRO HD3  H N N 309 
PRO HXT  H N N 310 
SER N    N N N 311 
SER CA   C N S 312 
SER C    C N N 313 
SER O    O N N 314 
SER CB   C N N 315 
SER OG   O N N 316 
SER OXT  O N N 317 
SER H    H N N 318 
SER H2   H N N 319 
SER HA   H N N 320 
SER HB2  H N N 321 
SER HB3  H N N 322 
SER HG   H N N 323 
SER HXT  H N N 324 
THR N    N N N 325 
THR CA   C N S 326 
THR C    C N N 327 
THR O    O N N 328 
THR CB   C N R 329 
THR OG1  O N N 330 
THR CG2  C N N 331 
THR OXT  O N N 332 
THR H    H N N 333 
THR H2   H N N 334 
THR HA   H N N 335 
THR HB   H N N 336 
THR HG1  H N N 337 
THR HG21 H N N 338 
THR HG22 H N N 339 
THR HG23 H N N 340 
THR HXT  H N N 341 
TRP N    N N N 342 
TRP CA   C N S 343 
TRP C    C N N 344 
TRP O    O N N 345 
TRP CB   C N N 346 
TRP CG   C Y N 347 
TRP CD1  C Y N 348 
TRP CD2  C Y N 349 
TRP NE1  N Y N 350 
TRP CE2  C Y N 351 
TRP CE3  C Y N 352 
TRP CZ2  C Y N 353 
TRP CZ3  C Y N 354 
TRP CH2  C Y N 355 
TRP OXT  O N N 356 
TRP H    H N N 357 
TRP H2   H N N 358 
TRP HA   H N N 359 
TRP HB2  H N N 360 
TRP HB3  H N N 361 
TRP HD1  H N N 362 
TRP HE1  H N N 363 
TRP HE3  H N N 364 
TRP HZ2  H N N 365 
TRP HZ3  H N N 366 
TRP HH2  H N N 367 
TRP HXT  H N N 368 
TYR N    N N N 369 
TYR CA   C N S 370 
TYR C    C N N 371 
TYR O    O N N 372 
TYR CB   C N N 373 
TYR CG   C Y N 374 
TYR CD1  C Y N 375 
TYR CD2  C Y N 376 
TYR CE1  C Y N 377 
TYR CE2  C Y N 378 
TYR CZ   C Y N 379 
TYR OH   O N N 380 
TYR OXT  O N N 381 
TYR H    H N N 382 
TYR H2   H N N 383 
TYR HA   H N N 384 
TYR HB2  H N N 385 
TYR HB3  H N N 386 
TYR HD1  H N N 387 
TYR HD2  H N N 388 
TYR HE1  H N N 389 
TYR HE2  H N N 390 
TYR HH   H N N 391 
TYR HXT  H N N 392 
VAL N    N N N 393 
VAL CA   C N S 394 
VAL C    C N N 395 
VAL O    O N N 396 
VAL CB   C N N 397 
VAL CG1  C N N 398 
VAL CG2  C N N 399 
VAL OXT  O N N 400 
VAL H    H N N 401 
VAL H2   H N N 402 
VAL HA   H N N 403 
VAL HB   H N N 404 
VAL HG11 H N N 405 
VAL HG12 H N N 406 
VAL HG13 H N N 407 
VAL HG21 H N N 408 
VAL HG22 H N N 409 
VAL HG23 H N N 410 
VAL HXT  H N N 411 
# 
loop_
_chem_comp_bond.comp_id 
_chem_comp_bond.atom_id_1 
_chem_comp_bond.atom_id_2 
_chem_comp_bond.value_order 
_chem_comp_bond.pdbx_aromatic_flag 
_chem_comp_bond.pdbx_stereo_config 
_chem_comp_bond.pdbx_ordinal 
ALA N   CA   sing N N 1   
ALA N   H    sing N N 2   
ALA N   H2   sing N N 3   
ALA CA  C    sing N N 4   
ALA CA  CB   sing N N 5   
ALA CA  HA   sing N N 6   
ALA C   O    doub N N 7   
ALA C   OXT  sing N N 8   
ALA CB  HB1  sing N N 9   
ALA CB  HB2  sing N N 10  
ALA CB  HB3  sing N N 11  
ALA OXT HXT  sing N N 12  
ARG N   CA   sing N N 13  
ARG N   H    sing N N 14  
ARG N   H2   sing N N 15  
ARG CA  C    sing N N 16  
ARG CA  CB   sing N N 17  
ARG CA  HA   sing N N 18  
ARG C   O    doub N N 19  
ARG C   OXT  sing N N 20  
ARG CB  CG   sing N N 21  
ARG CB  HB2  sing N N 22  
ARG CB  HB3  sing N N 23  
ARG CG  CD   sing N N 24  
ARG CG  HG2  sing N N 25  
ARG CG  HG3  sing N N 26  
ARG CD  NE   sing N N 27  
ARG CD  HD2  sing N N 28  
ARG CD  HD3  sing N N 29  
ARG NE  CZ   sing N N 30  
ARG NE  HE   sing N N 31  
ARG CZ  NH1  sing N N 32  
ARG CZ  NH2  doub N N 33  
ARG NH1 HH11 sing N N 34  
ARG NH1 HH12 sing N N 35  
ARG NH2 HH21 sing N N 36  
ARG NH2 HH22 sing N N 37  
ARG OXT HXT  sing N N 38  
ASN N   CA   sing N N 39  
ASN N   H    sing N N 40  
ASN N   H2   sing N N 41  
ASN CA  C    sing N N 42  
ASN CA  CB   sing N N 43  
ASN CA  HA   sing N N 44  
ASN C   O    doub N N 45  
ASN C   OXT  sing N N 46  
ASN CB  CG   sing N N 47  
ASN CB  HB2  sing N N 48  
ASN CB  HB3  sing N N 49  
ASN CG  OD1  doub N N 50  
ASN CG  ND2  sing N N 51  
ASN ND2 HD21 sing N N 52  
ASN ND2 HD22 sing N N 53  
ASN OXT HXT  sing N N 54  
ASP N   CA   sing N N 55  
ASP N   H    sing N N 56  
ASP N   H2   sing N N 57  
ASP CA  C    sing N N 58  
ASP CA  CB   sing N N 59  
ASP CA  HA   sing N N 60  
ASP C   O    doub N N 61  
ASP C   OXT  sing N N 62  
ASP CB  CG   sing N N 63  
ASP CB  HB2  sing N N 64  
ASP CB  HB3  sing N N 65  
ASP CG  OD1  doub N N 66  
ASP CG  OD2  sing N N 67  
ASP OD2 HD2  sing N N 68  
ASP OXT HXT  sing N N 69  
BGC C2  C3   sing N N 70  
BGC C2  C1   sing N N 71  
BGC C2  O2   sing N N 72  
BGC C2  H2   sing N N 73  
BGC C3  C4   sing N N 74  
BGC C3  O3   sing N N 75  
BGC C3  H3   sing N N 76  
BGC C4  C5   sing N N 77  
BGC C4  O4   sing N N 78  
BGC C4  H4   sing N N 79  
BGC C5  C6   sing N N 80  
BGC C5  O5   sing N N 81  
BGC C5  H5   sing N N 82  
BGC C6  O6   sing N N 83  
BGC C6  H61  sing N N 84  
BGC C6  H62  sing N N 85  
BGC C1  O1   sing N N 86  
BGC C1  O5   sing N N 87  
BGC C1  H1   sing N N 88  
BGC O1  HO1  sing N N 89  
BGC O2  HO2  sing N N 90  
BGC O3  HO3  sing N N 91  
BGC O4  HO4  sing N N 92  
BGC O6  HO6  sing N N 93  
CYS N   CA   sing N N 94  
CYS N   H    sing N N 95  
CYS N   H2   sing N N 96  
CYS CA  C    sing N N 97  
CYS CA  CB   sing N N 98  
CYS CA  HA   sing N N 99  
CYS C   O    doub N N 100 
CYS C   OXT  sing N N 101 
CYS CB  SG   sing N N 102 
CYS CB  HB2  sing N N 103 
CYS CB  HB3  sing N N 104 
CYS SG  HG   sing N N 105 
CYS OXT HXT  sing N N 106 
GLN N   CA   sing N N 107 
GLN N   H    sing N N 108 
GLN N   H2   sing N N 109 
GLN CA  C    sing N N 110 
GLN CA  CB   sing N N 111 
GLN CA  HA   sing N N 112 
GLN C   O    doub N N 113 
GLN C   OXT  sing N N 114 
GLN CB  CG   sing N N 115 
GLN CB  HB2  sing N N 116 
GLN CB  HB3  sing N N 117 
GLN CG  CD   sing N N 118 
GLN CG  HG2  sing N N 119 
GLN CG  HG3  sing N N 120 
GLN CD  OE1  doub N N 121 
GLN CD  NE2  sing N N 122 
GLN NE2 HE21 sing N N 123 
GLN NE2 HE22 sing N N 124 
GLN OXT HXT  sing N N 125 
GLU N   CA   sing N N 126 
GLU N   H    sing N N 127 
GLU N   H2   sing N N 128 
GLU CA  C    sing N N 129 
GLU CA  CB   sing N N 130 
GLU CA  HA   sing N N 131 
GLU C   O    doub N N 132 
GLU C   OXT  sing N N 133 
GLU CB  CG   sing N N 134 
GLU CB  HB2  sing N N 135 
GLU CB  HB3  sing N N 136 
GLU CG  CD   sing N N 137 
GLU CG  HG2  sing N N 138 
GLU CG  HG3  sing N N 139 
GLU CD  OE1  doub N N 140 
GLU CD  OE2  sing N N 141 
GLU OE2 HE2  sing N N 142 
GLU OXT HXT  sing N N 143 
GLY N   CA   sing N N 144 
GLY N   H    sing N N 145 
GLY N   H2   sing N N 146 
GLY CA  C    sing N N 147 
GLY CA  HA2  sing N N 148 
GLY CA  HA3  sing N N 149 
GLY C   O    doub N N 150 
GLY C   OXT  sing N N 151 
GLY OXT HXT  sing N N 152 
HIS N   CA   sing N N 153 
HIS N   H    sing N N 154 
HIS N   H2   sing N N 155 
HIS CA  C    sing N N 156 
HIS CA  CB   sing N N 157 
HIS CA  HA   sing N N 158 
HIS C   O    doub N N 159 
HIS C   OXT  sing N N 160 
HIS CB  CG   sing N N 161 
HIS CB  HB2  sing N N 162 
HIS CB  HB3  sing N N 163 
HIS CG  ND1  sing Y N 164 
HIS CG  CD2  doub Y N 165 
HIS ND1 CE1  doub Y N 166 
HIS ND1 HD1  sing N N 167 
HIS CD2 NE2  sing Y N 168 
HIS CD2 HD2  sing N N 169 
HIS CE1 NE2  sing Y N 170 
HIS CE1 HE1  sing N N 171 
HIS NE2 HE2  sing N N 172 
HIS OXT HXT  sing N N 173 
ILE N   CA   sing N N 174 
ILE N   H    sing N N 175 
ILE N   H2   sing N N 176 
ILE CA  C    sing N N 177 
ILE CA  CB   sing N N 178 
ILE CA  HA   sing N N 179 
ILE C   O    doub N N 180 
ILE C   OXT  sing N N 181 
ILE CB  CG1  sing N N 182 
ILE CB  CG2  sing N N 183 
ILE CB  HB   sing N N 184 
ILE CG1 CD1  sing N N 185 
ILE CG1 HG12 sing N N 186 
ILE CG1 HG13 sing N N 187 
ILE CG2 HG21 sing N N 188 
ILE CG2 HG22 sing N N 189 
ILE CG2 HG23 sing N N 190 
ILE CD1 HD11 sing N N 191 
ILE CD1 HD12 sing N N 192 
ILE CD1 HD13 sing N N 193 
ILE OXT HXT  sing N N 194 
LEU N   CA   sing N N 195 
LEU N   H    sing N N 196 
LEU N   H2   sing N N 197 
LEU CA  C    sing N N 198 
LEU CA  CB   sing N N 199 
LEU CA  HA   sing N N 200 
LEU C   O    doub N N 201 
LEU C   OXT  sing N N 202 
LEU CB  CG   sing N N 203 
LEU CB  HB2  sing N N 204 
LEU CB  HB3  sing N N 205 
LEU CG  CD1  sing N N 206 
LEU CG  CD2  sing N N 207 
LEU CG  HG   sing N N 208 
LEU CD1 HD11 sing N N 209 
LEU CD1 HD12 sing N N 210 
LEU CD1 HD13 sing N N 211 
LEU CD2 HD21 sing N N 212 
LEU CD2 HD22 sing N N 213 
LEU CD2 HD23 sing N N 214 
LEU OXT HXT  sing N N 215 
LYS N   CA   sing N N 216 
LYS N   H    sing N N 217 
LYS N   H2   sing N N 218 
LYS CA  C    sing N N 219 
LYS CA  CB   sing N N 220 
LYS CA  HA   sing N N 221 
LYS C   O    doub N N 222 
LYS C   OXT  sing N N 223 
LYS CB  CG   sing N N 224 
LYS CB  HB2  sing N N 225 
LYS CB  HB3  sing N N 226 
LYS CG  CD   sing N N 227 
LYS CG  HG2  sing N N 228 
LYS CG  HG3  sing N N 229 
LYS CD  CE   sing N N 230 
LYS CD  HD2  sing N N 231 
LYS CD  HD3  sing N N 232 
LYS CE  NZ   sing N N 233 
LYS CE  HE2  sing N N 234 
LYS CE  HE3  sing N N 235 
LYS NZ  HZ1  sing N N 236 
LYS NZ  HZ2  sing N N 237 
LYS NZ  HZ3  sing N N 238 
LYS OXT HXT  sing N N 239 
MET N   CA   sing N N 240 
MET N   H    sing N N 241 
MET N   H2   sing N N 242 
MET CA  C    sing N N 243 
MET CA  CB   sing N N 244 
MET CA  HA   sing N N 245 
MET C   O    doub N N 246 
MET C   OXT  sing N N 247 
MET CB  CG   sing N N 248 
MET CB  HB2  sing N N 249 
MET CB  HB3  sing N N 250 
MET CG  SD   sing N N 251 
MET CG  HG2  sing N N 252 
MET CG  HG3  sing N N 253 
MET SD  CE   sing N N 254 
MET CE  HE1  sing N N 255 
MET CE  HE2  sing N N 256 
MET CE  HE3  sing N N 257 
MET OXT HXT  sing N N 258 
PHE N   CA   sing N N 259 
PHE N   H    sing N N 260 
PHE N   H2   sing N N 261 
PHE CA  C    sing N N 262 
PHE CA  CB   sing N N 263 
PHE CA  HA   sing N N 264 
PHE C   O    doub N N 265 
PHE C   OXT  sing N N 266 
PHE CB  CG   sing N N 267 
PHE CB  HB2  sing N N 268 
PHE CB  HB3  sing N N 269 
PHE CG  CD1  doub Y N 270 
PHE CG  CD2  sing Y N 271 
PHE CD1 CE1  sing Y N 272 
PHE CD1 HD1  sing N N 273 
PHE CD2 CE2  doub Y N 274 
PHE CD2 HD2  sing N N 275 
PHE CE1 CZ   doub Y N 276 
PHE CE1 HE1  sing N N 277 
PHE CE2 CZ   sing Y N 278 
PHE CE2 HE2  sing N N 279 
PHE CZ  HZ   sing N N 280 
PHE OXT HXT  sing N N 281 
PRO N   CA   sing N N 282 
PRO N   CD   sing N N 283 
PRO N   H    sing N N 284 
PRO CA  C    sing N N 285 
PRO CA  CB   sing N N 286 
PRO CA  HA   sing N N 287 
PRO C   O    doub N N 288 
PRO C   OXT  sing N N 289 
PRO CB  CG   sing N N 290 
PRO CB  HB2  sing N N 291 
PRO CB  HB3  sing N N 292 
PRO CG  CD   sing N N 293 
PRO CG  HG2  sing N N 294 
PRO CG  HG3  sing N N 295 
PRO CD  HD2  sing N N 296 
PRO CD  HD3  sing N N 297 
PRO OXT HXT  sing N N 298 
SER N   CA   sing N N 299 
SER N   H    sing N N 300 
SER N   H2   sing N N 301 
SER CA  C    sing N N 302 
SER CA  CB   sing N N 303 
SER CA  HA   sing N N 304 
SER C   O    doub N N 305 
SER C   OXT  sing N N 306 
SER CB  OG   sing N N 307 
SER CB  HB2  sing N N 308 
SER CB  HB3  sing N N 309 
SER OG  HG   sing N N 310 
SER OXT HXT  sing N N 311 
THR N   CA   sing N N 312 
THR N   H    sing N N 313 
THR N   H2   sing N N 314 
THR CA  C    sing N N 315 
THR CA  CB   sing N N 316 
THR CA  HA   sing N N 317 
THR C   O    doub N N 318 
THR C   OXT  sing N N 319 
THR CB  OG1  sing N N 320 
THR CB  CG2  sing N N 321 
THR CB  HB   sing N N 322 
THR OG1 HG1  sing N N 323 
THR CG2 HG21 sing N N 324 
THR CG2 HG22 sing N N 325 
THR CG2 HG23 sing N N 326 
THR OXT HXT  sing N N 327 
TRP N   CA   sing N N 328 
TRP N   H    sing N N 329 
TRP N   H2   sing N N 330 
TRP CA  C    sing N N 331 
TRP CA  CB   sing N N 332 
TRP CA  HA   sing N N 333 
TRP C   O    doub N N 334 
TRP C   OXT  sing N N 335 
TRP CB  CG   sing N N 336 
TRP CB  HB2  sing N N 337 
TRP CB  HB3  sing N N 338 
TRP CG  CD1  doub Y N 339 
TRP CG  CD2  sing Y N 340 
TRP CD1 NE1  sing Y N 341 
TRP CD1 HD1  sing N N 342 
TRP CD2 CE2  doub Y N 343 
TRP CD2 CE3  sing Y N 344 
TRP NE1 CE2  sing Y N 345 
TRP NE1 HE1  sing N N 346 
TRP CE2 CZ2  sing Y N 347 
TRP CE3 CZ3  doub Y N 348 
TRP CE3 HE3  sing N N 349 
TRP CZ2 CH2  doub Y N 350 
TRP CZ2 HZ2  sing N N 351 
TRP CZ3 CH2  sing Y N 352 
TRP CZ3 HZ3  sing N N 353 
TRP CH2 HH2  sing N N 354 
TRP OXT HXT  sing N N 355 
TYR N   CA   sing N N 356 
TYR N   H    sing N N 357 
TYR N   H2   sing N N 358 
TYR CA  C    sing N N 359 
TYR CA  CB   sing N N 360 
TYR CA  HA   sing N N 361 
TYR C   O    doub N N 362 
TYR C   OXT  sing N N 363 
TYR CB  CG   sing N N 364 
TYR CB  HB2  sing N N 365 
TYR CB  HB3  sing N N 366 
TYR CG  CD1  doub Y N 367 
TYR CG  CD2  sing Y N 368 
TYR CD1 CE1  sing Y N 369 
TYR CD1 HD1  sing N N 370 
TYR CD2 CE2  doub Y N 371 
TYR CD2 HD2  sing N N 372 
TYR CE1 CZ   doub Y N 373 
TYR CE1 HE1  sing N N 374 
TYR CE2 CZ   sing Y N 375 
TYR CE2 HE2  sing N N 376 
TYR CZ  OH   sing N N 377 
TYR OH  HH   sing N N 378 
TYR OXT HXT  sing N N 379 
VAL N   CA   sing N N 380 
VAL N   H    sing N N 381 
VAL N   H2   sing N N 382 
VAL CA  C    sing N N 383 
VAL CA  CB   sing N N 384 
VAL CA  HA   sing N N 385 
VAL C   O    doub N N 386 
VAL C   OXT  sing N N 387 
VAL CB  CG1  sing N N 388 
VAL CB  CG2  sing N N 389 
VAL CB  HB   sing N N 390 
VAL CG1 HG11 sing N N 391 
VAL CG1 HG12 sing N N 392 
VAL CG1 HG13 sing N N 393 
VAL CG2 HG21 sing N N 394 
VAL CG2 HG22 sing N N 395 
VAL CG2 HG23 sing N N 396 
VAL OXT HXT  sing N N 397 
# 
_em_admin.current_status     REL 
_em_admin.deposition_date    2024-03-30 
_em_admin.deposition_site    RCSB 
_em_admin.entry_id           9B8H 
_em_admin.last_update        2025-05-28 
_em_admin.map_release_date   2025-02-19 
_em_admin.title              'Cryo-EM structure of E. coli cellulose synthase subunit C with cellotetraose' 
# 
_em_ctf_correction.details                  ? 
_em_ctf_correction.em_image_processing_id   1 
_em_ctf_correction.id                       1 
_em_ctf_correction.type                     'PHASE FLIPPING AND AMPLITUDE CORRECTION' 
# 
_em_entity_assembly_naturalsource.cell                 ? 
_em_entity_assembly_naturalsource.cellular_location    ? 
_em_entity_assembly_naturalsource.entity_assembly_id   1 
_em_entity_assembly_naturalsource.id                   2 
_em_entity_assembly_naturalsource.ncbi_tax_id          562 
_em_entity_assembly_naturalsource.organism             'Escherichia coli' 
_em_entity_assembly_naturalsource.organelle            ? 
_em_entity_assembly_naturalsource.organ                ? 
_em_entity_assembly_naturalsource.strain               ? 
_em_entity_assembly_naturalsource.tissue               ? 
_em_entity_assembly_naturalsource.details              ? 
# 
_em_entity_assembly_recombinant.cell                 ? 
_em_entity_assembly_recombinant.entity_assembly_id   1 
_em_entity_assembly_recombinant.id                   2 
_em_entity_assembly_recombinant.ncbi_tax_id          562 
_em_entity_assembly_recombinant.organism             'Escherichia coli' 
_em_entity_assembly_recombinant.plasmid              ? 
_em_entity_assembly_recombinant.strain               ? 
# 
_em_image_processing.details              ? 
_em_image_processing.id                   1 
_em_image_processing.image_recording_id   1 
# 
_em_image_recording.average_exposure_time               ? 
_em_image_recording.avg_electron_dose_per_subtomogram   ? 
_em_image_recording.avg_electron_dose_per_image         50 
_em_image_recording.details                             ? 
_em_image_recording.detector_mode                       ? 
_em_image_recording.film_or_detector_model              'GATAN K3 BIOQUANTUM (6k x 4k)' 
_em_image_recording.id                                  1 
_em_image_recording.imaging_id                          1 
_em_image_recording.num_diffraction_images              ? 
_em_image_recording.num_grids_imaged                    ? 
_em_image_recording.num_real_images                     ? 
# 
loop_
_em_software.category 
_em_software.details 
_em_software.id 
_em_software.image_processing_id 
_em_software.fitting_id 
_em_software.imaging_id 
_em_software.name 
_em_software.version 
'PARTICLE SELECTION'            ? 1  1 ? ? ?      ? 
'IMAGE ACQUISITION'             ? 2  ? ? 1 ?      ? 
MASKING                         ? 3  ? ? ? ?      ? 
'CTF CORRECTION'                ? 4  1 ? ? ?      ? 
'LAYERLINE INDEXING'            ? 5  ? ? ? ?      ? 
'DIFFRACTION INDEXING'          ? 6  ? ? ? ?      ? 
'MODEL FITTING'                 ? 7  ? ? ? ?      ? 
'MODEL REFINEMENT'              ? 8  ? ? ? PHENIX ? 
OTHER                           ? 9  ? ? ? ?      ? 
'INITIAL EULER ASSIGNMENT'      ? 10 1 ? ? ?      ? 
'FINAL EULER ASSIGNMENT'        ? 11 1 ? ? ?      ? 
CLASSIFICATION                  ? 12 1 ? ? ?      ? 
RECONSTRUCTION                  ? 13 1 ? ? ?      ? 
'VOLUME SELECTION'              ? 14 1 1 1 ?      ? 
'SERIES ALIGNMENT'              ? 15 1 1 1 ?      ? 
'MOLECULAR REPLACEMENT'         ? 16 1 1 1 ?      ? 
'LATTICE DISTORTION CORRECTION' ? 17 1 1 1 ?      ? 
'SYMMETRY DETERMINATION'        ? 18 1 1 1 ?      ? 
'CRYSTALLOGRAPHY MERGING'       ? 19 1 1 1 ?      ? 
# 
_em_specimen.concentration           ? 
_em_specimen.details                 ? 
_em_specimen.embedding_applied       NO 
_em_specimen.experiment_id           1 
_em_specimen.id                      1 
_em_specimen.shadowing_applied       NO 
_em_specimen.staining_applied        NO 
_em_specimen.vitrification_applied   YES 
# 
_pdbx_audit_support.funding_organization   
'National Institutes of Health/National Institute of General Medical Sciences (NIH/NIGMS)' 
_pdbx_audit_support.country                'United States' 
_pdbx_audit_support.grant_number           R35GM144130 
_pdbx_audit_support.ordinal                1 
# 
loop_
_pdbx_entity_branch_list.entity_id 
_pdbx_entity_branch_list.comp_id 
_pdbx_entity_branch_list.num 
_pdbx_entity_branch_list.hetero 
2 BGC 1 n 
2 BGC 2 n 
2 BGC 3 n 
2 BGC 4 n 
# 
_atom_sites.entry_id                    9B8H 
_atom_sites.Cartn_transf_matrix[1][1]   ? 
_atom_sites.Cartn_transf_matrix[1][2]   ? 
_atom_sites.Cartn_transf_matrix[1][3]   ? 
_atom_sites.Cartn_transf_matrix[2][1]   ? 
_atom_sites.Cartn_transf_matrix[2][2]   ? 
_atom_sites.Cartn_transf_matrix[2][3]   ? 
_atom_sites.Cartn_transf_matrix[3][1]   ? 
_atom_sites.Cartn_transf_matrix[3][2]   ? 
_atom_sites.Cartn_transf_matrix[3][3]   ? 
_atom_sites.Cartn_transf_vector[1]      ? 
_atom_sites.Cartn_transf_vector[2]      ? 
_atom_sites.Cartn_transf_vector[3]      ? 
_atom_sites.Cartn_transform_axes        ? 
_atom_sites.fract_transf_matrix[1][1]   1.000000 
_atom_sites.fract_transf_matrix[1][2]   0.000000 
_atom_sites.fract_transf_matrix[1][3]   0.000000 
_atom_sites.fract_transf_matrix[2][1]   0.000000 
_atom_sites.fract_transf_matrix[2][2]   1.000000 
_atom_sites.fract_transf_matrix[2][3]   0.000000 
_atom_sites.fract_transf_matrix[3][1]   0.000000 
_atom_sites.fract_transf_matrix[3][2]   0.000000 
_atom_sites.fract_transf_matrix[3][3]   1.000000 
_atom_sites.fract_transf_vector[1]      0.00000 
_atom_sites.fract_transf_vector[2]      0.00000 
_atom_sites.fract_transf_vector[3]      0.00000 
_atom_sites.solution_primary            ? 
_atom_sites.solution_secondary          ? 
_atom_sites.solution_hydrogens          ? 
_atom_sites.special_details             ? 
# 
loop_
_atom_type.symbol 
C 
N 
O 
S 
# 
loop_
_atom_site.group_PDB 
_atom_site.id 
_atom_site.type_symbol 
_atom_site.label_atom_id 
_atom_site.label_alt_id 
_atom_site.label_comp_id 
_atom_site.label_asym_id 
_atom_site.label_entity_id 
_atom_site.label_seq_id 
_atom_site.pdbx_PDB_ins_code 
_atom_site.Cartn_x 
_atom_site.Cartn_y 
_atom_site.Cartn_z 
_atom_site.occupancy 
_atom_site.B_iso_or_equiv 
_atom_site.pdbx_formal_charge 
_atom_site.auth_seq_id 
_atom_site.auth_comp_id 
_atom_site.auth_asym_id 
_atom_site.auth_atom_id 
_atom_site.pdbx_PDB_model_num 
ATOM   1    N N   . LEU A 1 560  ? 193.178 187.202 136.238 1.00 178.80 ? 571  LEU A N   1 
ATOM   2    C CA  . LEU A 1 560  ? 194.431 187.920 136.037 1.00 178.80 ? 571  LEU A CA  1 
ATOM   3    C C   . LEU A 1 560  ? 195.621 187.081 136.492 1.00 178.80 ? 571  LEU A C   1 
ATOM   4    O O   . LEU A 1 560  ? 195.530 186.340 137.471 1.00 178.80 ? 571  LEU A O   1 
ATOM   5    C CB  . LEU A 1 560  ? 194.415 189.254 136.786 1.00 178.80 ? 571  LEU A CB  1 
ATOM   6    C CG  . LEU A 1 560  ? 193.324 190.256 136.401 1.00 178.80 ? 571  LEU A CG  1 
ATOM   7    C CD1 . LEU A 1 560  ? 192.146 190.170 137.361 1.00 178.80 ? 571  LEU A CD1 1 
ATOM   8    C CD2 . LEU A 1 560  ? 193.884 191.669 136.358 1.00 178.80 ? 571  LEU A CD2 1 
ATOM   9    N N   . GLN A 1 561  ? 196.737 187.200 135.768 1.00 180.31 ? 572  GLN A N   1 
ATOM   10   C CA  . GLN A 1 561  ? 197.945 186.477 136.153 1.00 180.31 ? 572  GLN A CA  1 
ATOM   11   C C   . GLN A 1 561  ? 198.471 186.963 137.498 1.00 180.31 ? 572  GLN A C   1 
ATOM   12   O O   . GLN A 1 561  ? 198.938 186.162 138.316 1.00 180.31 ? 572  GLN A O   1 
ATOM   13   C CB  . GLN A 1 561  ? 199.014 186.619 135.068 1.00 180.31 ? 572  GLN A CB  1 
ATOM   14   C CG  . GLN A 1 561  ? 199.289 188.051 134.629 1.00 180.31 ? 572  GLN A CG  1 
ATOM   15   C CD  . GLN A 1 561  ? 198.404 188.491 133.479 1.00 180.31 ? 572  GLN A CD  1 
ATOM   16   O OE1 . GLN A 1 561  ? 197.179 188.527 133.602 1.00 180.31 ? 572  GLN A OE1 1 
ATOM   17   N NE2 . GLN A 1 561  ? 199.021 188.827 132.353 1.00 180.31 ? 572  GLN A NE2 1 
ATOM   18   N N   . SER A 1 562  ? 198.406 188.274 137.744 1.00 180.94 ? 573  SER A N   1 
ATOM   19   C CA  . SER A 1 562  ? 198.819 188.806 139.038 1.00 180.94 ? 573  SER A CA  1 
ATOM   20   C C   . SER A 1 562  ? 197.880 188.360 140.151 1.00 180.94 ? 573  SER A C   1 
ATOM   21   O O   . SER A 1 562  ? 198.320 188.171 141.291 1.00 180.94 ? 573  SER A O   1 
ATOM   22   C CB  . SER A 1 562  ? 198.893 190.331 138.982 1.00 180.94 ? 573  SER A CB  1 
ATOM   23   O OG  . SER A 1 562  ? 199.275 190.869 140.236 1.00 180.94 ? 573  SER A OG  1 
ATOM   24   N N   . ASP A 1 563  ? 196.590 188.198 139.845 1.00 178.86 ? 574  ASP A N   1 
ATOM   25   C CA  . ASP A 1 563  ? 195.647 187.708 140.845 1.00 178.86 ? 574  ASP A CA  1 
ATOM   26   C C   . ASP A 1 563  ? 196.004 186.296 141.290 1.00 178.86 ? 574  ASP A C   1 
ATOM   27   O O   . ASP A 1 563  ? 195.922 185.972 142.481 1.00 178.86 ? 574  ASP A O   1 
ATOM   28   C CB  . ASP A 1 563  ? 194.223 187.755 140.292 1.00 178.86 ? 574  ASP A CB  1 
ATOM   29   C CG  . ASP A 1 563  ? 193.202 187.202 141.266 1.00 178.86 ? 574  ASP A CG  1 
ATOM   30   O OD1 . ASP A 1 563  ? 193.070 187.763 142.374 1.00 178.86 ? 574  ASP A OD1 1 
ATOM   31   O OD2 . ASP A 1 563  ? 192.530 186.206 140.924 1.00 178.86 ? 574  ASP A OD2 1 
ATOM   32   N N   . GLN A 1 564  ? 196.398 185.438 140.345 1.00 179.37 ? 575  GLN A N   1 
ATOM   33   C CA  . GLN A 1 564  ? 196.841 184.096 140.705 1.00 179.37 ? 575  GLN A CA  1 
ATOM   34   C C   . GLN A 1 564  ? 198.124 184.133 141.524 1.00 179.37 ? 575  GLN A C   1 
ATOM   35   O O   . GLN A 1 564  ? 198.316 183.294 142.412 1.00 179.37 ? 575  GLN A O   1 
ATOM   36   C CB  . GLN A 1 564  ? 197.036 183.251 139.446 1.00 179.37 ? 575  GLN A CB  1 
ATOM   37   C CG  . GLN A 1 564  ? 196.809 181.764 139.659 1.00 179.37 ? 575  GLN A CG  1 
ATOM   38   C CD  . GLN A 1 564  ? 195.382 181.344 139.359 1.00 179.37 ? 575  GLN A CD  1 
ATOM   39   O OE1 . GLN A 1 564  ? 194.836 181.668 138.305 1.00 179.37 ? 575  GLN A OE1 1 
ATOM   40   N NE2 . GLN A 1 564  ? 194.771 180.620 140.289 1.00 179.37 ? 575  GLN A NE2 1 
ATOM   41   N N   . VAL A 1 565  ? 199.015 185.084 141.235 1.00 176.76 ? 576  VAL A N   1 
ATOM   42   C CA  . VAL A 1 565  ? 200.232 185.230 142.026 1.00 176.76 ? 576  VAL A CA  1 
ATOM   43   C C   . VAL A 1 565  ? 199.897 185.647 143.454 1.00 176.76 ? 576  VAL A C   1 
ATOM   44   O O   . VAL A 1 565  ? 200.469 185.124 144.418 1.00 176.76 ? 576  VAL A O   1 
ATOM   45   C CB  . VAL A 1 565  ? 201.188 186.228 141.347 1.00 176.76 ? 576  VAL A CB  1 
ATOM   46   C CG1 . VAL A 1 565  ? 202.137 186.849 142.364 1.00 176.76 ? 576  VAL A CG1 1 
ATOM   47   C CG2 . VAL A 1 565  ? 201.966 185.543 140.234 1.00 176.76 ? 576  VAL A CG2 1 
ATOM   48   N N   . LEU A 1 566  ? 198.965 186.590 143.613 1.00 176.69 ? 577  LEU A N   1 
ATOM   49   C CA  . LEU A 1 566  ? 198.616 187.076 144.945 1.00 176.69 ? 577  LEU A CA  1 
ATOM   50   C C   . LEU A 1 566  ? 198.014 185.966 145.799 1.00 176.69 ? 577  LEU A C   1 
ATOM   51   O O   . LEU A 1 566  ? 198.388 185.793 146.965 1.00 176.69 ? 577  LEU A O   1 
ATOM   52   C CB  . LEU A 1 566  ? 197.651 188.258 144.837 1.00 176.69 ? 577  LEU A CB  1 
ATOM   53   C CG  . LEU A 1 566  ? 197.079 188.800 146.150 1.00 176.69 ? 577  LEU A CG  1 
ATOM   54   C CD1 . LEU A 1 566  ? 198.187 189.090 147.153 1.00 176.69 ? 577  LEU A CD1 1 
ATOM   55   C CD2 . LEU A 1 566  ? 196.242 190.045 145.904 1.00 176.69 ? 577  LEU A CD2 1 
ATOM   56   N N   . GLU A 1 567  ? 197.076 185.199 145.235 1.00 178.32 ? 578  GLU A N   1 
ATOM   57   C CA  . GLU A 1 567  ? 196.462 184.120 146.002 1.00 178.32 ? 578  GLU A CA  1 
ATOM   58   C C   . GLU A 1 567  ? 197.451 182.994 146.269 1.00 178.32 ? 578  GLU A C   1 
ATOM   59   O O   . GLU A 1 567  ? 197.282 182.236 147.231 1.00 178.32 ? 578  GLU A O   1 
ATOM   60   C CB  . GLU A 1 567  ? 195.222 183.589 145.279 1.00 178.32 ? 578  GLU A CB  1 
ATOM   61   C CG  . GLU A 1 567  ? 195.482 183.041 143.887 1.00 178.32 ? 578  GLU A CG  1 
ATOM   62   C CD  . GLU A 1 567  ? 195.773 181.552 143.888 1.00 178.32 ? 578  GLU A CD  1 
ATOM   63   O OE1 . GLU A 1 567  ? 195.409 180.875 144.872 1.00 178.32 ? 578  GLU A OE1 1 
ATOM   64   O OE2 . GLU A 1 567  ? 196.364 181.060 142.904 1.00 178.32 ? 578  GLU A OE2 1 
ATOM   65   N N   . THR A 1 568  ? 198.482 182.864 145.430 1.00 180.39 ? 579  THR A N   1 
ATOM   66   C CA  . THR A 1 568  ? 199.532 181.887 145.697 1.00 180.39 ? 579  THR A CA  1 
ATOM   67   C C   . THR A 1 568  ? 200.259 182.210 146.996 1.00 180.39 ? 579  THR A C   1 
ATOM   68   O O   . THR A 1 568  ? 200.546 181.313 147.798 1.00 180.39 ? 579  THR A O   1 
ATOM   69   C CB  . THR A 1 568  ? 200.517 181.837 144.528 1.00 180.39 ? 579  THR A CB  1 
ATOM   70   O OG1 . THR A 1 568  ? 199.800 181.628 143.305 1.00 180.39 ? 579  THR A OG1 1 
ATOM   71   C CG2 . THR A 1 568  ? 201.519 180.708 144.721 1.00 180.39 ? 579  THR A CG2 1 
ATOM   72   N N   . ALA A 1 569  ? 200.565 183.490 147.222 1.00 177.21 ? 580  ALA A N   1 
ATOM   73   C CA  . ALA A 1 569  ? 201.153 183.896 148.493 1.00 177.21 ? 580  ALA A CA  1 
ATOM   74   C C   . ALA A 1 569  ? 200.150 183.785 149.633 1.00 177.21 ? 580  ALA A C   1 
ATOM   75   O O   . ALA A 1 569  ? 200.537 183.486 150.769 1.00 177.21 ? 580  ALA A O   1 
ATOM   76   C CB  . ALA A 1 569  ? 201.691 185.324 148.393 1.00 177.21 ? 580  ALA A CB  1 
ATOM   77   N N   . ASN A 1 570  ? 198.865 184.025 149.355 1.00 175.15 ? 581  ASN A N   1 
ATOM   78   C CA  . ASN A 1 570  ? 197.838 183.902 150.382 1.00 175.15 ? 581  ASN A CA  1 
ATOM   79   C C   . ASN A 1 570  ? 197.678 182.470 150.874 1.00 175.15 ? 581  ASN A C   1 
ATOM   80   O O   . ASN A 1 570  ? 197.183 182.263 151.987 1.00 175.15 ? 581  ASN A O   1 
ATOM   81   C CB  . ASN A 1 570  ? 196.500 184.425 149.857 1.00 175.15 ? 581  ASN A CB  1 
ATOM   82   C CG  . ASN A 1 570  ? 196.569 185.879 149.430 1.00 175.15 ? 581  ASN A CG  1 
ATOM   83   O OD1 . ASN A 1 570  ? 197.401 186.642 149.920 1.00 175.15 ? 581  ASN A OD1 1 
ATOM   84   N ND2 . ASN A 1 570  ? 195.694 186.269 148.511 1.00 175.15 ? 581  ASN A ND2 1 
ATOM   85   N N   . ARG A 1 571  ? 198.076 181.482 150.076 1.00 176.64 ? 582  ARG A N   1 
ATOM   86   C CA  . ARG A 1 571  ? 198.069 180.090 150.504 1.00 176.64 ? 582  ARG A CA  1 
ATOM   87   C C   . ARG A 1 571  ? 199.339 179.702 151.251 1.00 176.64 ? 582  ARG A C   1 
ATOM   88   O O   . ARG A 1 571  ? 199.586 178.507 151.457 1.00 176.64 ? 582  ARG A O   1 
ATOM   89   C CB  . ARG A 1 571  ? 197.865 179.166 149.300 1.00 176.64 ? 582  ARG A CB  1 
ATOM   90   C CG  . ARG A 1 571  ? 196.551 179.374 148.555 1.00 176.64 ? 582  ARG A CG  1 
ATOM   91   C CD  . ARG A 1 571  ? 195.426 178.496 149.100 1.00 176.64 ? 582  ARG A CD  1 
ATOM   92   N NE  . ARG A 1 571  ? 195.189 178.690 150.525 1.00 176.64 ? 582  ARG A NE  1 
ATOM   93   C CZ  . ARG A 1 571  ? 194.539 179.723 151.045 1.00 176.64 ? 582  ARG A CZ  1 
ATOM   94   N NH1 . ARG A 1 571  ? 194.038 180.680 150.281 1.00 176.64 ? 582  ARG A NH1 1 
ATOM   95   N NH2 . ARG A 1 571  ? 194.387 179.797 152.364 1.00 176.64 ? 582  ARG A NH2 1 
ATOM   96   N N   . LEU A 1 572  ? 200.146 180.684 151.659 1.00 177.72 ? 583  LEU A N   1 
ATOM   97   C CA  . LEU A 1 572  ? 201.383 180.428 152.385 1.00 177.72 ? 583  LEU A CA  1 
ATOM   98   C C   . LEU A 1 572  ? 201.416 181.134 153.736 1.00 177.72 ? 583  LEU A C   1 
ATOM   99   O O   . LEU A 1 572  ? 202.456 181.116 154.406 1.00 177.72 ? 583  LEU A O   1 
ATOM   100  C CB  . LEU A 1 572  ? 202.593 180.847 151.539 1.00 177.72 ? 583  LEU A CB  1 
ATOM   101  C CG  . LEU A 1 572  ? 203.938 180.174 151.826 1.00 177.72 ? 583  LEU A CG  1 
ATOM   102  C CD1 . LEU A 1 572  ? 203.804 178.660 151.777 1.00 177.72 ? 583  LEU A CD1 1 
ATOM   103  C CD2 . LEU A 1 572  ? 204.999 180.653 150.849 1.00 177.72 ? 583  LEU A CD2 1 
ATOM   104  N N   . ARG A 1 573  ? 200.308 181.750 154.160 1.00 174.12 ? 584  ARG A N   1 
ATOM   105  C CA  . ARG A 1 573  ? 200.281 182.428 155.451 1.00 174.12 ? 584  ARG A CA  1 
ATOM   106  C C   . ARG A 1 573  ? 200.395 181.459 156.621 1.00 174.12 ? 584  ARG A C   1 
ATOM   107  O O   . ARG A 1 573  ? 200.647 181.899 157.748 1.00 174.12 ? 584  ARG A O   1 
ATOM   108  C CB  . ARG A 1 573  ? 199.006 183.260 155.593 1.00 174.12 ? 584  ARG A CB  1 
ATOM   109  C CG  . ARG A 1 573  ? 198.640 184.069 154.360 1.00 174.12 ? 584  ARG A CG  1 
ATOM   110  C CD  . ARG A 1 573  ? 197.153 184.397 154.325 1.00 174.12 ? 584  ARG A CD  1 
ATOM   111  N NE  . ARG A 1 573  ? 196.319 183.201 154.267 1.00 174.12 ? 584  ARG A NE  1 
ATOM   112  C CZ  . ARG A 1 573  ? 195.687 182.674 155.307 1.00 174.12 ? 584  ARG A CZ  1 
ATOM   113  N NH1 . ARG A 1 573  ? 195.768 183.215 156.512 1.00 174.12 ? 584  ARG A NH1 1 
ATOM   114  N NH2 . ARG A 1 573  ? 194.956 181.577 155.134 1.00 174.12 ? 584  ARG A NH2 1 
ATOM   115  N N   . GLU A 1 574  ? 200.205 180.158 156.384 1.00 174.40 ? 585  GLU A N   1 
ATOM   116  C CA  . GLU A 1 574  ? 200.414 179.178 157.445 1.00 174.40 ? 585  GLU A CA  1 
ATOM   117  C C   . GLU A 1 574  ? 201.859 179.200 157.925 1.00 174.40 ? 585  GLU A C   1 
ATOM   118  O O   . GLU A 1 574  ? 202.123 179.119 159.131 1.00 174.40 ? 585  GLU A O   1 
ATOM   119  C CB  . GLU A 1 574  ? 200.029 177.780 156.958 1.00 174.40 ? 585  GLU A CB  1 
ATOM   120  C CG  . GLU A 1 574  ? 198.743 177.728 156.145 1.00 174.40 ? 585  GLU A CG  1 
ATOM   121  C CD  . GLU A 1 574  ? 198.976 177.947 154.662 1.00 174.40 ? 585  GLU A CD  1 
ATOM   122  O OE1 . GLU A 1 574  ? 199.843 177.257 154.086 1.00 174.40 ? 585  GLU A OE1 1 
ATOM   123  O OE2 . GLU A 1 574  ? 198.291 178.810 154.073 1.00 174.40 ? 585  GLU A OE2 1 
ATOM   124  N N   . SER A 1 575  ? 202.806 179.309 156.998 1.00 173.09 ? 586  SER A N   1 
ATOM   125  C CA  . SER A 1 575  ? 204.209 179.499 157.337 1.00 173.09 ? 586  SER A CA  1 
ATOM   126  C C   . SER A 1 575  ? 204.466 180.981 157.579 1.00 173.09 ? 586  SER A C   1 
ATOM   127  O O   . SER A 1 575  ? 203.903 181.836 156.887 1.00 173.09 ? 586  SER A O   1 
ATOM   128  C CB  . SER A 1 575  ? 205.114 178.973 156.223 1.00 173.09 ? 586  SER A CB  1 
ATOM   129  O OG  . SER A 1 575  ? 206.472 179.286 156.479 1.00 173.09 ? 586  SER A OG  1 
ATOM   130  N N   . GLY A 1 576  ? 205.315 181.281 158.561 1.00 170.51 ? 587  GLY A N   1 
ATOM   131  C CA  . GLY A 1 576  ? 205.577 182.663 158.923 1.00 170.51 ? 587  GLY A CA  1 
ATOM   132  C C   . GLY A 1 576  ? 206.479 183.412 157.964 1.00 170.51 ? 587  GLY A C   1 
ATOM   133  O O   . GLY A 1 576  ? 206.647 184.625 158.125 1.00 170.51 ? 587  GLY A O   1 
ATOM   134  N N   . LYS A 1 577  ? 207.060 182.726 156.980 1.00 170.41 ? 588  LYS A N   1 
ATOM   135  C CA  . LYS A 1 577  ? 207.976 183.343 156.031 1.00 170.41 ? 588  LYS A CA  1 
ATOM   136  C C   . LYS A 1 577  ? 207.318 183.664 154.692 1.00 170.41 ? 588  LYS A C   1 
ATOM   137  O O   . LYS A 1 577  ? 207.994 183.627 153.657 1.00 170.41 ? 588  LYS A O   1 
ATOM   138  C CB  . LYS A 1 577  ? 209.192 182.441 155.812 1.00 170.41 ? 588  LYS A CB  1 
ATOM   139  C CG  . LYS A 1 577  ? 209.848 181.944 157.094 1.00 170.41 ? 588  LYS A CG  1 
ATOM   140  C CD  . LYS A 1 577  ? 210.874 182.936 157.626 1.00 170.41 ? 588  LYS A CD  1 
ATOM   141  C CE  . LYS A 1 577  ? 210.290 183.817 158.721 1.00 170.41 ? 588  LYS A CE  1 
ATOM   142  N NZ  . LYS A 1 577  ? 211.250 184.866 159.162 1.00 170.41 ? 588  LYS A NZ  1 
ATOM   143  N N   . GLU A 1 578  ? 206.019 183.976 154.686 1.00 172.20 ? 589  GLU A N   1 
ATOM   144  C CA  . GLU A 1 578  ? 205.349 184.302 153.431 1.00 172.20 ? 589  GLU A CA  1 
ATOM   145  C C   . GLU A 1 578  ? 205.774 185.667 152.901 1.00 172.20 ? 589  GLU A C   1 
ATOM   146  O O   . GLU A 1 578  ? 205.721 185.903 151.687 1.00 172.20 ? 589  GLU A O   1 
ATOM   147  C CB  . GLU A 1 578  ? 203.830 184.240 153.613 1.00 172.20 ? 589  GLU A CB  1 
ATOM   148  C CG  . GLU A 1 578  ? 203.226 185.360 154.455 1.00 172.20 ? 589  GLU A CG  1 
ATOM   149  C CD  . GLU A 1 578  ? 203.398 185.144 155.949 1.00 172.20 ? 589  GLU A CD  1 
ATOM   150  O OE1 . GLU A 1 578  ? 204.072 184.169 156.343 1.00 172.20 ? 589  GLU A OE1 1 
ATOM   151  O OE2 . GLU A 1 578  ? 202.856 185.955 156.730 1.00 172.20 ? 589  GLU A OE2 1 
ATOM   152  N N   . ALA A 1 579  ? 206.201 186.572 153.787 1.00 174.17 ? 590  ALA A N   1 
ATOM   153  C CA  . ALA A 1 579  ? 206.673 187.879 153.340 1.00 174.17 ? 590  ALA A CA  1 
ATOM   154  C C   . ALA A 1 579  ? 207.935 187.749 152.497 1.00 174.17 ? 590  ALA A C   1 
ATOM   155  O O   . ALA A 1 579  ? 208.067 188.403 151.458 1.00 174.17 ? 590  ALA A O   1 
ATOM   156  C CB  . ALA A 1 579  ? 206.921 188.789 154.542 1.00 174.17 ? 590  ALA A CB  1 
ATOM   157  N N   . GLU A 1 580  ? 208.872 186.901 152.927 1.00 174.65 ? 591  GLU A N   1 
ATOM   158  C CA  . GLU A 1 580  ? 210.066 186.656 152.127 1.00 174.65 ? 591  GLU A CA  1 
ATOM   159  C C   . GLU A 1 580  ? 209.709 186.024 150.787 1.00 174.65 ? 591  GLU A C   1 
ATOM   160  O O   . GLU A 1 580  ? 210.284 186.382 149.750 1.00 174.65 ? 591  GLU A O   1 
ATOM   161  C CB  . GLU A 1 580  ? 211.040 185.768 152.903 1.00 174.65 ? 591  GLU A CB  1 
ATOM   162  C CG  . GLU A 1 580  ? 211.622 186.411 154.162 1.00 174.65 ? 591  GLU A CG  1 
ATOM   163  C CD  . GLU A 1 580  ? 210.724 186.260 155.379 1.00 174.65 ? 591  GLU A CD  1 
ATOM   164  O OE1 . GLU A 1 580  ? 209.498 186.099 155.203 1.00 174.65 ? 591  GLU A OE1 1 
ATOM   165  O OE2 . GLU A 1 580  ? 211.244 186.300 156.515 1.00 174.65 ? 591  GLU A OE2 1 
ATOM   166  N N   . ALA A 1 581  ? 208.768 185.077 150.790 1.00 172.44 ? 592  ALA A N   1 
ATOM   167  C CA  . ALA A 1 581  ? 208.352 184.452 149.541 1.00 172.44 ? 592  ALA A CA  1 
ATOM   168  C C   . ALA A 1 581  ? 207.788 185.486 148.578 1.00 172.44 ? 592  ALA A C   1 
ATOM   169  O O   . ALA A 1 581  ? 208.122 185.485 147.388 1.00 172.44 ? 592  ALA A O   1 
ATOM   170  C CB  . ALA A 1 581  ? 207.325 183.356 149.819 1.00 172.44 ? 592  ALA A CB  1 
ATOM   171  N N   . GLU A 1 582  ? 206.950 186.395 149.082 1.00 173.92 ? 593  GLU A N   1 
ATOM   172  C CA  . GLU A 1 582  ? 206.455 187.488 148.252 1.00 173.92 ? 593  GLU A CA  1 
ATOM   173  C C   . GLU A 1 582  ? 207.606 188.363 147.771 1.00 173.92 ? 593  GLU A C   1 
ATOM   174  O O   . GLU A 1 582  ? 207.596 188.852 146.635 1.00 173.92 ? 593  GLU A O   1 
ATOM   175  C CB  . GLU A 1 582  ? 205.442 188.318 149.042 1.00 173.92 ? 593  GLU A CB  1 
ATOM   176  C CG  . GLU A 1 582  ? 204.775 189.454 148.274 1.00 173.92 ? 593  GLU A CG  1 
ATOM   177  C CD  . GLU A 1 582  ? 204.488 189.109 146.823 1.00 173.92 ? 593  GLU A CD  1 
ATOM   178  O OE1 . GLU A 1 582  ? 205.133 189.691 145.927 1.00 173.92 ? 593  GLU A OE1 1 
ATOM   179  O OE2 . GLU A 1 582  ? 203.614 188.249 146.576 1.00 173.92 ? 593  GLU A OE2 1 
ATOM   180  N N   . ALA A 1 583  ? 208.609 188.568 148.628 1.00 172.82 ? 594  ALA A N   1 
ATOM   181  C CA  . ALA A 1 583  ? 209.747 189.400 148.257 1.00 172.82 ? 594  ALA A CA  1 
ATOM   182  C C   . ALA A 1 583  ? 210.503 188.819 147.069 1.00 172.82 ? 594  ALA A C   1 
ATOM   183  O O   . ALA A 1 583  ? 210.850 189.549 146.133 1.00 172.82 ? 594  ALA A O   1 
ATOM   184  C CB  . ALA A 1 583  ? 210.686 189.568 149.451 1.00 172.82 ? 594  ALA A CB  1 
ATOM   185  N N   . MET A 1 584  ? 210.783 187.514 147.086 1.00 172.51 ? 595  MET A N   1 
ATOM   186  C CA  . MET A 1 584  ? 211.468 186.941 145.926 1.00 172.51 ? 595  MET A CA  1 
ATOM   187  C C   . MET A 1 584  ? 210.529 186.791 144.732 1.00 172.51 ? 595  MET A C   1 
ATOM   188  O O   . MET A 1 584  ? 210.985 186.794 143.583 1.00 172.51 ? 595  MET A O   1 
ATOM   189  C CB  . MET A 1 584  ? 212.143 185.599 146.228 1.00 172.51 ? 595  MET A CB  1 
ATOM   190  C CG  . MET A 1 584  ? 211.306 184.540 146.902 1.00 172.51 ? 595  MET A CG  1 
ATOM   191  S SD  . MET A 1 584  ? 212.328 183.538 148.017 1.00 172.51 ? 595  MET A SD  1 
ATOM   192  C CE  . MET A 1 584  ? 212.566 184.549 149.471 1.00 172.51 ? 595  MET A CE  1 
ATOM   193  N N   . LEU A 1 585  ? 209.222 186.652 144.972 1.00 171.72 ? 596  LEU A N   1 
ATOM   194  C CA  . LEU A 1 585  ? 208.287 186.541 143.855 1.00 171.72 ? 596  LEU A CA  1 
ATOM   195  C C   . LEU A 1 585  ? 208.166 187.855 143.092 1.00 171.72 ? 596  LEU A C   1 
ATOM   196  O O   . LEU A 1 585  ? 208.021 187.855 141.864 1.00 171.72 ? 596  LEU A O   1 
ATOM   197  C CB  . LEU A 1 585  ? 206.917 186.083 144.358 1.00 171.72 ? 596  LEU A CB  1 
ATOM   198  C CG  . LEU A 1 585  ? 206.564 184.616 144.090 1.00 171.72 ? 596  LEU A CG  1 
ATOM   199  C CD1 . LEU A 1 585  ? 207.498 183.673 144.833 1.00 171.72 ? 596  LEU A CD1 1 
ATOM   200  C CD2 . LEU A 1 585  ? 205.117 184.335 144.464 1.00 171.72 ? 596  LEU A CD2 1 
ATOM   201  N N   . ARG A 1 586  ? 208.219 188.984 143.799 1.00 171.25 ? 597  ARG A N   1 
ATOM   202  C CA  . ARG A 1 586  ? 208.033 190.291 143.181 1.00 171.25 ? 597  ARG A CA  1 
ATOM   203  C C   . ARG A 1 586  ? 209.328 190.894 142.627 1.00 171.25 ? 597  ARG A C   1 
ATOM   204  O O   . ARG A 1 586  ? 209.388 192.113 142.417 1.00 171.25 ? 597  ARG A O   1 
ATOM   205  C CB  . ARG A 1 586  ? 207.379 191.254 144.178 1.00 171.25 ? 597  ARG A CB  1 
ATOM   206  C CG  . ARG A 1 586  ? 208.319 191.848 145.218 1.00 171.25 ? 597  ARG A CG  1 
ATOM   207  C CD  . ARG A 1 586  ? 207.783 193.179 145.717 1.00 171.25 ? 597  ARG A CD  1 
ATOM   208  N NE  . ARG A 1 586  ? 208.774 193.930 146.478 1.00 171.25 ? 597  ARG A NE  1 
ATOM   209  C CZ  . ARG A 1 586  ? 209.133 193.654 147.724 1.00 171.25 ? 597  ARG A CZ  1 
ATOM   210  N NH1 . ARG A 1 586  ? 208.587 192.653 148.396 1.00 171.25 ? 597  ARG A NH1 1 
ATOM   211  N NH2 . ARG A 1 586  ? 210.059 194.405 148.314 1.00 171.25 ? 597  ARG A NH2 1 
ATOM   212  N N   . GLN A 1 587  ? 210.354 190.081 142.368 1.00 173.01 ? 598  GLN A N   1 
ATOM   213  C CA  . GLN A 1 587  ? 211.596 190.606 141.812 1.00 173.01 ? 598  GLN A CA  1 
ATOM   214  C C   . GLN A 1 587  ? 211.405 191.240 140.440 1.00 173.01 ? 598  GLN A C   1 
ATOM   215  O O   . GLN A 1 587  ? 212.173 192.138 140.080 1.00 173.01 ? 598  GLN A O   1 
ATOM   216  C CB  . GLN A 1 587  ? 212.649 189.499 141.732 1.00 173.01 ? 598  GLN A CB  1 
ATOM   217  C CG  . GLN A 1 587  ? 214.077 189.993 141.910 1.00 173.01 ? 598  GLN A CG  1 
ATOM   218  C CD  . GLN A 1 587  ? 215.032 188.888 142.315 1.00 173.01 ? 598  GLN A CD  1 
ATOM   219  O OE1 . GLN A 1 587  ? 214.612 187.782 142.655 1.00 173.01 ? 598  GLN A OE1 1 
ATOM   220  N NE2 . GLN A 1 587  ? 216.327 189.183 142.282 1.00 173.01 ? 598  GLN A NE2 1 
ATOM   221  N N   . GLN A 1 588  ? 210.413 190.800 139.674 1.00 175.26 ? 599  GLN A N   1 
ATOM   222  C CA  . GLN A 1 588  ? 210.001 191.448 138.440 1.00 175.26 ? 599  GLN A CA  1 
ATOM   223  C C   . GLN A 1 588  ? 209.121 192.648 138.756 1.00 175.26 ? 599  GLN A C   1 
ATOM   224  O O   . GLN A 1 588  ? 208.568 192.744 139.855 1.00 175.26 ? 599  GLN A O   1 
ATOM   225  C CB  . GLN A 1 588  ? 209.245 190.458 137.546 1.00 175.26 ? 599  GLN A CB  1 
ATOM   226  C CG  . GLN A 1 588  ? 208.116 189.720 138.244 1.00 175.26 ? 599  GLN A CG  1 
ATOM   227  C CD  . GLN A 1 588  ? 207.868 188.346 137.652 1.00 175.26 ? 599  GLN A CD  1 
ATOM   228  O OE1 . GLN A 1 588  ? 208.070 188.126 136.458 1.00 175.26 ? 599  GLN A OE1 1 
ATOM   229  N NE2 . GLN A 1 588  ? 207.429 187.413 138.488 1.00 175.26 ? 599  GLN A NE2 1 
ATOM   230  N N   . PRO A 1 589  ? 208.991 193.598 137.829 1.00 175.01 ? 600  PRO A N   1 
ATOM   231  C CA  . PRO A 1 589  ? 208.168 194.795 138.085 1.00 175.01 ? 600  PRO A CA  1 
ATOM   232  C C   . PRO A 1 589  ? 206.787 194.425 138.595 1.00 175.01 ? 600  PRO A C   1 
ATOM   233  O O   . PRO A 1 589  ? 205.984 193.820 137.868 1.00 175.01 ? 600  PRO A O   1 
ATOM   234  C CB  . PRO A 1 589  ? 208.091 195.467 136.708 1.00 175.01 ? 600  PRO A CB  1 
ATOM   235  C CG  . PRO A 1 589  ? 209.357 195.070 136.033 1.00 175.01 ? 600  PRO A CG  1 
ATOM   236  C CD  . PRO A 1 589  ? 209.771 193.724 136.583 1.00 175.01 ? 600  PRO A CD  1 
ATOM   237  N N   . PRO A 1 590  ? 206.474 194.772 139.843 1.00 171.54 ? 601  PRO A N   1 
ATOM   238  C CA  . PRO A 1 590  ? 205.220 194.330 140.474 1.00 171.54 ? 601  PRO A CA  1 
ATOM   239  C C   . PRO A 1 590  ? 204.062 195.318 140.405 1.00 171.54 ? 601  PRO A C   1 
ATOM   240  O O   . PRO A 1 590  ? 203.023 195.042 141.015 1.00 171.54 ? 601  PRO A O   1 
ATOM   241  C CB  . PRO A 1 590  ? 205.652 194.129 141.937 1.00 171.54 ? 601  PRO A CB  1 
ATOM   242  C CG  . PRO A 1 590  ? 207.081 194.696 142.054 1.00 171.54 ? 601  PRO A CG  1 
ATOM   243  C CD  . PRO A 1 590  ? 207.334 195.470 140.806 1.00 171.54 ? 601  PRO A CD  1 
ATOM   244  N N   . SER A 1 591  ? 204.212 196.437 139.699 1.00 168.83 ? 602  SER A N   1 
ATOM   245  C CA  . SER A 1 591  ? 203.209 197.513 139.660 1.00 168.83 ? 602  SER A CA  1 
ATOM   246  C C   . SER A 1 591  ? 203.042 198.018 141.092 1.00 168.83 ? 602  SER A C   1 
ATOM   247  O O   . SER A 1 591  ? 204.054 198.295 141.756 1.00 168.83 ? 602  SER A O   1 
ATOM   248  C CB  . SER A 1 591  ? 201.938 197.019 138.977 1.00 168.83 ? 602  SER A CB  1 
ATOM   249  O OG  . SER A 1 591  ? 202.140 196.849 137.585 1.00 168.83 ? 602  SER A OG  1 
ATOM   250  N N   . THR A 1 592  ? 201.818 198.155 141.609 1.00 162.27 ? 603  THR A N   1 
ATOM   251  C CA  . THR A 1 592  ? 201.617 198.687 142.951 1.00 162.27 ? 603  THR A CA  1 
ATOM   252  C C   . THR A 1 592  ? 200.595 197.935 143.792 1.00 162.27 ? 603  THR A C   1 
ATOM   253  O O   . THR A 1 592  ? 200.558 198.152 145.007 1.00 162.27 ? 603  THR A O   1 
ATOM   254  C CB  . THR A 1 592  ? 201.203 200.167 142.885 1.00 162.27 ? 603  THR A CB  1 
ATOM   255  O OG1 . THR A 1 592  ? 201.475 200.798 144.143 1.00 162.27 ? 603  THR A OG1 1 
ATOM   256  C CG2 . THR A 1 592  ? 199.722 200.299 142.563 1.00 162.27 ? 603  THR A CG2 1 
ATOM   257  N N   . ARG A 1 593  ? 199.769 197.068 143.203 1.00 164.55 ? 604  ARG A N   1 
ATOM   258  C CA  . ARG A 1 593  ? 198.743 196.375 143.979 1.00 164.55 ? 604  ARG A CA  1 
ATOM   259  C C   . ARG A 1 593  ? 199.362 195.371 144.947 1.00 164.55 ? 604  ARG A C   1 
ATOM   260  O O   . ARG A 1 593  ? 199.056 195.370 146.147 1.00 164.55 ? 604  ARG A O   1 
ATOM   261  C CB  . ARG A 1 593  ? 197.756 195.690 143.031 1.00 164.55 ? 604  ARG A CB  1 
ATOM   262  C CG  . ARG A 1 593  ? 196.945 194.568 143.653 1.00 164.55 ? 604  ARG A CG  1 
ATOM   263  C CD  . ARG A 1 593  ? 196.878 193.378 142.712 1.00 164.55 ? 604  ARG A CD  1 
ATOM   264  N NE  . ARG A 1 593  ? 195.901 192.384 143.138 1.00 164.55 ? 604  ARG A NE  1 
ATOM   265  C CZ  . ARG A 1 593  ? 195.661 191.251 142.493 1.00 164.55 ? 604  ARG A CZ  1 
ATOM   266  N NH1 . ARG A 1 593  ? 196.317 190.933 141.389 1.00 164.55 ? 604  ARG A NH1 1 
ATOM   267  N NH2 . ARG A 1 593  ? 194.738 190.418 142.964 1.00 164.55 ? 604  ARG A NH2 1 
ATOM   268  N N   . ILE A 1 594  ? 200.254 194.515 144.445 1.00 160.94 ? 605  ILE A N   1 
ATOM   269  C CA  . ILE A 1 594  ? 200.927 193.561 145.321 1.00 160.94 ? 605  ILE A CA  1 
ATOM   270  C C   . ILE A 1 594  ? 201.877 194.286 146.265 1.00 160.94 ? 605  ILE A C   1 
ATOM   271  O O   . ILE A 1 594  ? 202.103 193.840 147.397 1.00 160.94 ? 605  ILE A O   1 
ATOM   272  C CB  . ILE A 1 594  ? 201.649 192.482 144.488 1.00 160.94 ? 605  ILE A CB  1 
ATOM   273  C CG1 . ILE A 1 594  ? 202.330 191.458 145.399 1.00 160.94 ? 605  ILE A CG1 1 
ATOM   274  C CG2 . ILE A 1 594  ? 202.651 193.112 143.543 1.00 160.94 ? 605  ILE A CG2 1 
ATOM   275  C CD1 . ILE A 1 594  ? 201.381 190.754 146.342 1.00 160.94 ? 605  ILE A CD1 1 
ATOM   276  N N   . ASP A 1 595  ? 202.438 195.416 145.826 1.00 159.17 ? 606  ASP A N   1 
ATOM   277  C CA  . ASP A 1 595  ? 203.263 196.223 146.718 1.00 159.17 ? 606  ASP A CA  1 
ATOM   278  C C   . ASP A 1 595  ? 202.450 196.737 147.899 1.00 159.17 ? 606  ASP A C   1 
ATOM   279  O O   . ASP A 1 595  ? 202.911 196.693 149.044 1.00 159.17 ? 606  ASP A O   1 
ATOM   280  C CB  . ASP A 1 595  ? 203.891 197.384 145.947 1.00 159.17 ? 606  ASP A CB  1 
ATOM   281  C CG  . ASP A 1 595  ? 204.916 196.921 144.930 1.00 159.17 ? 606  ASP A CG  1 
ATOM   282  O OD1 . ASP A 1 595  ? 205.142 195.697 144.828 1.00 159.17 ? 606  ASP A OD1 1 
ATOM   283  O OD2 . ASP A 1 595  ? 205.496 197.780 144.235 1.00 159.17 ? 606  ASP A OD2 1 
ATOM   284  N N   . LEU A 1 596  ? 201.229 197.210 147.643 1.00 157.60 ? 607  LEU A N   1 
ATOM   285  C CA  . LEU A 1 596  ? 200.361 197.649 148.731 1.00 157.60 ? 607  LEU A CA  1 
ATOM   286  C C   . LEU A 1 596  ? 199.943 196.477 149.611 1.00 157.60 ? 607  LEU A C   1 
ATOM   287  O O   . LEU A 1 596  ? 199.820 196.624 150.832 1.00 157.60 ? 607  LEU A O   1 
ATOM   288  C CB  . LEU A 1 596  ? 199.132 198.364 148.169 1.00 157.60 ? 607  LEU A CB  1 
ATOM   289  C CG  . LEU A 1 596  ? 199.169 199.894 148.136 1.00 157.60 ? 607  LEU A CG  1 
ATOM   290  C CD1 . LEU A 1 596  ? 198.890 200.468 149.517 1.00 157.60 ? 607  LEU A CD1 1 
ATOM   291  C CD2 . LEU A 1 596  ? 200.497 200.405 147.597 1.00 157.60 ? 607  LEU A CD2 1 
ATOM   292  N N   . THR A 1 597  ? 199.712 195.309 149.007 1.00 155.20 ? 608  THR A N   1 
ATOM   293  C CA  . THR A 1 597  ? 199.362 194.129 149.795 1.00 155.20 ? 608  THR A CA  1 
ATOM   294  C C   . THR A 1 597  ? 200.484 193.760 150.761 1.00 155.20 ? 608  THR A C   1 
ATOM   295  O O   . THR A 1 597  ? 200.245 193.515 151.951 1.00 155.20 ? 608  THR A O   1 
ATOM   296  C CB  . THR A 1 597  ? 199.042 192.955 148.869 1.00 155.20 ? 608  THR A CB  1 
ATOM   297  O OG1 . THR A 1 597  ? 198.104 193.373 147.870 1.00 155.20 ? 608  THR A OG1 1 
ATOM   298  C CG2 . THR A 1 597  ? 198.450 191.801 149.663 1.00 155.20 ? 608  THR A CG2 1 
ATOM   299  N N   . LEU A 1 598  ? 201.725 193.729 150.269 1.00 155.11 ? 609  LEU A N   1 
ATOM   300  C CA  . LEU A 1 598  ? 202.843 193.402 151.148 1.00 155.11 ? 609  LEU A CA  1 
ATOM   301  C C   . LEU A 1 598  ? 203.128 194.531 152.131 1.00 155.11 ? 609  LEU A C   1 
ATOM   302  O O   . LEU A 1 598  ? 203.626 194.276 153.231 1.00 155.11 ? 609  LEU A O   1 
ATOM   303  C CB  . LEU A 1 598  ? 204.094 193.065 150.334 1.00 155.11 ? 609  LEU A CB  1 
ATOM   304  C CG  . LEU A 1 598  ? 204.799 194.153 149.526 1.00 155.11 ? 609  LEU A CG  1 
ATOM   305  C CD1 . LEU A 1 598  ? 205.991 194.711 150.287 1.00 155.11 ? 609  LEU A CD1 1 
ATOM   306  C CD2 . LEU A 1 598  ? 205.243 193.586 148.193 1.00 155.11 ? 609  LEU A CD2 1 
ATOM   307  N N   . ALA A 1 599  ? 202.813 195.776 151.766 1.00 152.46 ? 610  ALA A N   1 
ATOM   308  C CA  . ALA A 1 599  ? 202.915 196.869 152.725 1.00 152.46 ? 610  ALA A CA  1 
ATOM   309  C C   . ALA A 1 599  ? 201.932 196.684 153.874 1.00 152.46 ? 610  ALA A C   1 
ATOM   310  O O   . ALA A 1 599  ? 202.275 196.920 155.036 1.00 152.46 ? 610  ALA A O   1 
ATOM   311  C CB  . ALA A 1 599  ? 202.682 198.208 152.025 1.00 152.46 ? 610  ALA A CB  1 
ATOM   312  N N   . ASP A 1 600  ? 200.705 196.258 153.567 1.00 150.28 ? 611  ASP A N   1 
ATOM   313  C CA  . ASP A 1 600  ? 199.742 195.943 154.620 1.00 150.28 ? 611  ASP A CA  1 
ATOM   314  C C   . ASP A 1 600  ? 200.222 194.773 155.471 1.00 150.28 ? 611  ASP A C   1 
ATOM   315  O O   . ASP A 1 600  ? 200.079 194.789 156.701 1.00 150.28 ? 611  ASP A O   1 
ATOM   316  C CB  . ASP A 1 600  ? 198.375 195.637 154.010 1.00 150.28 ? 611  ASP A CB  1 
ATOM   317  C CG  . ASP A 1 600  ? 197.812 196.805 153.226 1.00 150.28 ? 611  ASP A CG  1 
ATOM   318  O OD1 . ASP A 1 600  ? 198.434 197.888 153.242 1.00 150.28 ? 611  ASP A OD1 1 
ATOM   319  O OD2 . ASP A 1 600  ? 196.749 196.639 152.593 1.00 150.28 ? 611  ASP A OD2 1 
ATOM   320  N N   . TRP A 1 601  ? 200.788 193.747 154.829 1.00 144.36 ? 612  TRP A N   1 
ATOM   321  C CA  . TRP A 1 601  ? 201.347 192.620 155.572 1.00 144.36 ? 612  TRP A CA  1 
ATOM   322  C C   . TRP A 1 601  ? 202.438 193.081 156.531 1.00 144.36 ? 612  TRP A C   1 
ATOM   323  O O   . TRP A 1 601  ? 202.484 192.651 157.689 1.00 144.36 ? 612  TRP A O   1 
ATOM   324  C CB  . TRP A 1 601  ? 201.902 191.575 154.603 1.00 144.36 ? 612  TRP A CB  1 
ATOM   325  C CG  . TRP A 1 601  ? 200.865 190.678 154.001 1.00 144.36 ? 612  TRP A CG  1 
ATOM   326  C CD1 . TRP A 1 601  ? 200.540 190.573 152.680 1.00 144.36 ? 612  TRP A CD1 1 
ATOM   327  C CD2 . TRP A 1 601  ? 200.029 189.744 154.695 1.00 144.36 ? 612  TRP A CD2 1 
ATOM   328  N NE1 . TRP A 1 601  ? 199.548 189.640 152.509 1.00 144.36 ? 612  TRP A NE1 1 
ATOM   329  C CE2 . TRP A 1 601  ? 199.217 189.115 153.731 1.00 144.36 ? 612  TRP A CE2 1 
ATOM   330  C CE3 . TRP A 1 601  ? 199.886 189.381 156.038 1.00 144.36 ? 612  TRP A CE3 1 
ATOM   331  C CZ2 . TRP A 1 601  ? 198.276 188.145 154.066 1.00 144.36 ? 612  TRP A CZ2 1 
ATOM   332  C CZ3 . TRP A 1 601  ? 198.951 188.418 156.368 1.00 144.36 ? 612  TRP A CZ3 1 
ATOM   333  C CH2 . TRP A 1 601  ? 198.158 187.811 155.387 1.00 144.36 ? 612  TRP A CH2 1 
ATOM   334  N N   . ALA A 1 602  ? 203.326 193.958 156.061 1.00 142.86 ? 613  ALA A N   1 
ATOM   335  C CA  . ALA A 1 602  ? 204.382 194.492 156.914 1.00 142.86 ? 613  ALA A CA  1 
ATOM   336  C C   . ALA A 1 602  ? 203.804 195.365 158.021 1.00 142.86 ? 613  ALA A C   1 
ATOM   337  O O   . ALA A 1 602  ? 204.351 195.428 159.126 1.00 142.86 ? 613  ALA A O   1 
ATOM   338  C CB  . ALA A 1 602  ? 205.384 195.280 156.071 1.00 142.86 ? 613  ALA A CB  1 
ATOM   339  N N   . GLN A 1 603  ? 202.709 196.071 157.731 1.00 140.96 ? 614  GLN A N   1 
ATOM   340  C CA  . GLN A 1 603  ? 202.054 196.881 158.753 1.00 140.96 ? 614  GLN A CA  1 
ATOM   341  C C   . GLN A 1 603  ? 201.484 196.011 159.864 1.00 140.96 ? 614  GLN A C   1 
ATOM   342  O O   . GLN A 1 603  ? 201.538 196.379 161.044 1.00 140.96 ? 614  GLN A O   1 
ATOM   343  C CB  . GLN A 1 603  ? 200.951 197.732 158.120 1.00 140.96 ? 614  GLN A CB  1 
ATOM   344  C CG  . GLN A 1 603  ? 200.251 198.677 159.089 1.00 140.96 ? 614  GLN A CG  1 
ATOM   345  C CD  . GLN A 1 603  ? 198.951 198.108 159.626 1.00 140.96 ? 614  GLN A CD  1 
ATOM   346  O OE1 . GLN A 1 603  ? 198.531 197.017 159.242 1.00 140.96 ? 614  GLN A OE1 1 
ATOM   347  N NE2 . GLN A 1 603  ? 198.307 198.848 160.522 1.00 140.96 ? 614  GLN A NE2 1 
ATOM   348  N N   . GLN A 1 604  ? 200.930 194.850 159.506 1.00 143.94 ? 615  GLN A N   1 
ATOM   349  C CA  . GLN A 1 604  ? 200.349 193.969 160.516 1.00 143.94 ? 615  GLN A CA  1 
ATOM   350  C C   . GLN A 1 604  ? 201.411 193.358 161.425 1.00 143.94 ? 615  GLN A C   1 
ATOM   351  O O   . GLN A 1 604  ? 201.151 193.142 162.614 1.00 143.94 ? 615  GLN A O   1 
ATOM   352  C CB  . GLN A 1 604  ? 199.529 192.865 159.849 1.00 143.94 ? 615  GLN A CB  1 
ATOM   353  C CG  . GLN A 1 604  ? 198.288 193.366 159.129 1.00 143.94 ? 615  GLN A CG  1 
ATOM   354  C CD  . GLN A 1 604  ? 197.364 192.239 158.713 1.00 143.94 ? 615  GLN A CD  1 
ATOM   355  O OE1 . GLN A 1 604  ? 197.638 191.069 158.977 1.00 143.94 ? 615  GLN A OE1 1 
ATOM   356  N NE2 . GLN A 1 604  ? 196.269 192.586 158.046 1.00 143.94 ? 615  GLN A NE2 1 
ATOM   357  N N   . ARG A 1 605  ? 202.600 193.071 160.895 1.00 145.55 ? 616  ARG A N   1 
ATOM   358  C CA  . ARG A 1 605  ? 203.673 192.413 161.643 1.00 145.55 ? 616  ARG A CA  1 
ATOM   359  C C   . ARG A 1 605  ? 204.859 193.369 161.717 1.00 145.55 ? 616  ARG A C   1 
ATOM   360  O O   . ARG A 1 605  ? 205.521 193.614 160.704 1.00 145.55 ? 616  ARG A O   1 
ATOM   361  C CB  . ARG A 1 605  ? 204.079 191.108 160.967 1.00 145.55 ? 616  ARG A CB  1 
ATOM   362  C CG  . ARG A 1 605  ? 202.966 190.088 160.850 1.00 145.55 ? 616  ARG A CG  1 
ATOM   363  C CD  . ARG A 1 605  ? 202.675 189.802 159.380 1.00 145.55 ? 616  ARG A CD  1 
ATOM   364  N NE  . ARG A 1 605  ? 201.498 188.962 159.194 1.00 145.55 ? 616  ARG A NE  1 
ATOM   365  C CZ  . ARG A 1 605  ? 201.530 187.638 159.130 1.00 145.55 ? 616  ARG A CZ  1 
ATOM   366  N NH1 . ARG A 1 605  ? 202.667 186.971 159.224 1.00 145.55 ? 616  ARG A NH1 1 
ATOM   367  N NH2 . ARG A 1 605  ? 200.392 186.968 158.968 1.00 145.55 ? 616  ARG A NH2 1 
ATOM   368  N N   . ARG A 1 606  ? 205.123 193.907 162.915 1.00 143.07 ? 617  ARG A N   1 
ATOM   369  C CA  . ARG A 1 606  ? 206.237 194.829 163.133 1.00 143.07 ? 617  ARG A CA  1 
ATOM   370  C C   . ARG A 1 606  ? 205.952 196.146 162.409 1.00 143.07 ? 617  ARG A C   1 
ATOM   371  O O   . ARG A 1 606  ? 205.040 196.214 161.579 1.00 143.07 ? 617  ARG A O   1 
ATOM   372  C CB  . ARG A 1 606  ? 207.547 194.130 162.710 1.00 143.07 ? 617  ARG A CB  1 
ATOM   373  C CG  . ARG A 1 606  ? 208.901 194.823 162.899 1.00 143.07 ? 617  ARG A CG  1 
ATOM   374  C CD  . ARG A 1 606  ? 209.140 195.825 161.790 1.00 143.07 ? 617  ARG A CD  1 
ATOM   375  N NE  . ARG A 1 606  ? 208.655 195.271 160.533 1.00 143.07 ? 617  ARG A NE  1 
ATOM   376  C CZ  . ARG A 1 606  ? 208.186 195.989 159.522 1.00 143.07 ? 617  ARG A CZ  1 
ATOM   377  N NH1 . ARG A 1 606  ? 208.143 197.310 159.572 1.00 143.07 ? 617  ARG A NH1 1 
ATOM   378  N NH2 . ARG A 1 606  ? 207.734 195.363 158.439 1.00 143.07 ? 617  ARG A NH2 1 
ATOM   379  N N   . ASP A 1 607  ? 206.686 197.211 162.731 1.00 142.63 ? 618  ASP A N   1 
ATOM   380  C CA  . ASP A 1 607  ? 206.380 198.520 162.171 1.00 142.63 ? 618  ASP A CA  1 
ATOM   381  C C   . ASP A 1 607  ? 207.655 199.332 161.978 1.00 142.63 ? 618  ASP A C   1 
ATOM   382  O O   . ASP A 1 607  ? 208.768 198.862 162.225 1.00 142.63 ? 618  ASP A O   1 
ATOM   383  C CB  . ASP A 1 607  ? 205.395 199.281 163.065 1.00 142.63 ? 618  ASP A CB  1 
ATOM   384  C CG  . ASP A 1 607  ? 203.956 199.050 162.665 1.00 142.63 ? 618  ASP A CG  1 
ATOM   385  O OD1 . ASP A 1 607  ? 203.708 198.804 161.467 1.00 142.63 ? 618  ASP A OD1 1 
ATOM   386  O OD2 . ASP A 1 607  ? 203.074 199.105 163.548 1.00 142.63 ? 618  ASP A OD2 1 
ATOM   387  N N   . TYR A 1 608  ? 207.461 200.566 161.504 1.00 145.51 ? 619  TYR A N   1 
ATOM   388  C CA  . TYR A 1 608  ? 208.490 201.594 161.353 1.00 145.51 ? 619  TYR A CA  1 
ATOM   389  C C   . TYR A 1 608  ? 209.477 201.304 160.225 1.00 145.51 ? 619  TYR A C   1 
ATOM   390  O O   . TYR A 1 608  ? 209.364 201.887 159.143 1.00 145.51 ? 619  TYR A O   1 
ATOM   391  C CB  . TYR A 1 608  ? 209.243 201.813 162.673 1.00 145.51 ? 619  TYR A CB  1 
ATOM   392  C CG  . TYR A 1 608  ? 208.367 201.756 163.909 1.00 145.51 ? 619  TYR A CG  1 
ATOM   393  C CD1 . TYR A 1 608  ? 207.265 202.591 164.040 1.00 145.51 ? 619  TYR A CD1 1 
ATOM   394  C CD2 . TYR A 1 608  ? 208.650 200.877 164.946 1.00 145.51 ? 619  TYR A CD2 1 
ATOM   395  C CE1 . TYR A 1 608  ? 206.464 202.546 165.165 1.00 145.51 ? 619  TYR A CE1 1 
ATOM   396  C CE2 . TYR A 1 608  ? 207.855 200.826 166.076 1.00 145.51 ? 619  TYR A CE2 1 
ATOM   397  C CZ  . TYR A 1 608  ? 206.763 201.663 166.179 1.00 145.51 ? 619  TYR A CZ  1 
ATOM   398  O OH  . TYR A 1 608  ? 205.968 201.618 167.300 1.00 145.51 ? 619  TYR A OH  1 
ATOM   399  N N   . THR A 1 609  ? 210.439 200.409 160.456 1.00 145.74 ? 620  THR A N   1 
ATOM   400  C CA  . THR A 1 609  ? 211.572 200.256 159.545 1.00 145.74 ? 620  THR A CA  1 
ATOM   401  C C   . THR A 1 609  ? 211.167 199.788 158.149 1.00 145.74 ? 620  THR A C   1 
ATOM   402  O O   . THR A 1 609  ? 211.267 200.544 157.174 1.00 145.74 ? 620  THR A O   1 
ATOM   403  C CB  . THR A 1 609  ? 212.593 199.282 160.143 1.00 145.74 ? 620  THR A CB  1 
ATOM   404  O OG1 . THR A 1 609  ? 211.910 198.163 160.723 1.00 145.74 ? 620  THR A OG1 1 
ATOM   405  C CG2 . THR A 1 609  ? 213.427 199.973 161.217 1.00 145.74 ? 620  THR A CG2 1 
ATOM   406  N N   . ALA A 1 610  ? 210.682 198.550 158.052 1.00 146.79 ? 621  ALA A N   1 
ATOM   407  C CA  . ALA A 1 610  ? 210.281 198.017 156.729 1.00 146.79 ? 621  ALA A CA  1 
ATOM   408  C C   . ALA A 1 610  ? 209.043 198.763 156.228 1.00 146.79 ? 621  ALA A C   1 
ATOM   409  O O   . ALA A 1 610  ? 208.888 198.912 154.998 1.00 146.79 ? 621  ALA A O   1 
ATOM   410  C CB  . ALA A 1 610  ? 210.044 196.528 156.803 1.00 146.79 ? 621  ALA A CB  1 
ATOM   411  N N   . ALA A 1 611  ? 208.186 199.220 157.145 1.00 145.68 ? 622  ALA A N   1 
ATOM   412  C CA  . ALA A 1 611  ? 207.037 200.008 156.716 1.00 145.68 ? 622  ALA A CA  1 
ATOM   413  C C   . ALA A 1 611  ? 207.486 201.215 155.902 1.00 145.68 ? 622  ALA A C   1 
ATOM   414  O O   . ALA A 1 611  ? 206.946 201.489 154.826 1.00 145.68 ? 622  ALA A O   1 
ATOM   415  C CB  . ALA A 1 611  ? 206.216 200.446 157.930 1.00 145.68 ? 622  ALA A CB  1 
ATOM   416  N N   . ARG A 1 612  ? 208.507 201.930 156.384 1.00 146.81 ? 623  ARG A N   1 
ATOM   417  C CA  . ARG A 1 612  ? 209.042 203.053 155.621 1.00 146.81 ? 623  ARG A CA  1 
ATOM   418  C C   . ARG A 1 612  ? 209.809 202.582 154.393 1.00 146.81 ? 623  ARG A C   1 
ATOM   419  O O   . ARG A 1 612  ? 209.840 203.285 153.376 1.00 146.81 ? 623  ARG A O   1 
ATOM   420  C CB  . ARG A 1 612  ? 209.936 203.919 156.507 1.00 146.81 ? 623  ARG A CB  1 
ATOM   421  C CG  . ARG A 1 612  ? 209.171 204.837 157.446 1.00 146.81 ? 623  ARG A CG  1 
ATOM   422  C CD  . ARG A 1 612  ? 210.070 205.920 158.019 1.00 146.81 ? 623  ARG A CD  1 
ATOM   423  N NE  . ARG A 1 612  ? 209.362 206.771 158.967 1.00 146.81 ? 623  ARG A NE  1 
ATOM   424  C CZ  . ARG A 1 612  ? 209.087 208.053 158.763 1.00 146.81 ? 623  ARG A CZ  1 
ATOM   425  N NH1 . ARG A 1 612  ? 209.449 208.669 157.650 1.00 146.81 ? 623  ARG A NH1 1 
ATOM   426  N NH2 . ARG A 1 612  ? 208.432 208.733 159.699 1.00 146.81 ? 623  ARG A NH2 1 
ATOM   427  N N   . ALA A 1 613  ? 210.436 201.406 154.464 1.00 148.76 ? 624  ALA A N   1 
ATOM   428  C CA  . ALA A 1 613  ? 211.074 200.848 153.274 1.00 148.76 ? 624  ALA A CA  1 
ATOM   429  C C   . ALA A 1 613  ? 210.052 200.624 152.162 1.00 148.76 ? 624  ALA A C   1 
ATOM   430  O O   . ALA A 1 613  ? 210.263 201.031 151.011 1.00 148.76 ? 624  ALA A O   1 
ATOM   431  C CB  . ALA A 1 613  ? 211.789 199.543 153.625 1.00 148.76 ? 624  ALA A CB  1 
ATOM   432  N N   . ALA A 1 614  ? 208.924 199.991 152.495 1.00 147.52 ? 625  ALA A N   1 
ATOM   433  C CA  . ALA A 1 614  ? 207.848 199.817 151.527 1.00 147.52 ? 625  ALA A CA  1 
ATOM   434  C C   . ALA A 1 614  ? 207.242 201.153 151.120 1.00 147.52 ? 625  ALA A C   1 
ATOM   435  O O   . ALA A 1 614  ? 206.792 201.305 149.979 1.00 147.52 ? 625  ALA A O   1 
ATOM   436  C CB  . ALA A 1 614  ? 206.770 198.895 152.096 1.00 147.52 ? 625  ALA A CB  1 
ATOM   437  N N   . TYR A 1 615  ? 207.216 202.123 152.036 1.00 148.09 ? 626  TYR A N   1 
ATOM   438  C CA  . TYR A 1 615  ? 206.774 203.470 151.695 1.00 148.09 ? 626  TYR A CA  1 
ATOM   439  C C   . TYR A 1 615  ? 207.612 204.044 150.562 1.00 148.09 ? 626  TYR A C   1 
ATOM   440  O O   . TYR A 1 615  ? 207.077 204.555 149.574 1.00 148.09 ? 626  TYR A O   1 
ATOM   441  C CB  . TYR A 1 615  ? 206.851 204.364 152.936 1.00 148.09 ? 626  TYR A CB  1 
ATOM   442  C CG  . TYR A 1 615  ? 207.340 205.777 152.683 1.00 148.09 ? 626  TYR A CG  1 
ATOM   443  C CD1 . TYR A 1 615  ? 206.561 206.694 151.986 1.00 148.09 ? 626  TYR A CD1 1 
ATOM   444  C CD2 . TYR A 1 615  ? 208.584 206.191 153.140 1.00 148.09 ? 626  TYR A CD2 1 
ATOM   445  C CE1 . TYR A 1 615  ? 207.009 207.982 151.756 1.00 148.09 ? 626  TYR A CE1 1 
ATOM   446  C CE2 . TYR A 1 615  ? 209.040 207.476 152.914 1.00 148.09 ? 626  TYR A CE2 1 
ATOM   447  C CZ  . TYR A 1 615  ? 208.249 208.367 152.222 1.00 148.09 ? 626  TYR A CZ  1 
ATOM   448  O OH  . TYR A 1 615  ? 208.700 209.647 151.995 1.00 148.09 ? 626  TYR A OH  1 
ATOM   449  N N   . GLN A 1 616  ? 208.938 203.965 150.694 1.00 149.54 ? 627  GLN A N   1 
ATOM   450  C CA  . GLN A 1 616  ? 209.818 204.443 149.631 1.00 149.54 ? 627  GLN A CA  1 
ATOM   451  C C   . GLN A 1 616  ? 209.622 203.640 148.352 1.00 149.54 ? 627  GLN A C   1 
ATOM   452  O O   . GLN A 1 616  ? 209.572 204.208 147.252 1.00 149.54 ? 627  GLN A O   1 
ATOM   453  C CB  . GLN A 1 616  ? 211.278 204.378 150.079 1.00 149.54 ? 627  GLN A CB  1 
ATOM   454  C CG  . GLN A 1 616  ? 211.563 205.045 151.412 1.00 149.54 ? 627  GLN A CG  1 
ATOM   455  C CD  . GLN A 1 616  ? 212.752 204.429 152.124 1.00 149.54 ? 627  GLN A CD  1 
ATOM   456  O OE1 . GLN A 1 616  ? 212.625 203.904 153.230 1.00 149.54 ? 627  GLN A OE1 1 
ATOM   457  N NE2 . GLN A 1 616  ? 213.916 204.488 151.489 1.00 149.54 ? 627  GLN A NE2 1 
ATOM   458  N N   . ASN A 1 617  ? 209.500 202.315 148.479 1.00 151.55 ? 628  ASN A N   1 
ATOM   459  C CA  . ASN A 1 617  ? 209.351 201.465 147.301 1.00 151.55 ? 628  ASN A CA  1 
ATOM   460  C C   . ASN A 1 617  ? 208.106 201.837 146.505 1.00 151.55 ? 628  ASN A C   1 
ATOM   461  O O   . ASN A 1 617  ? 208.147 201.930 145.273 1.00 151.55 ? 628  ASN A O   1 
ATOM   462  C CB  . ASN A 1 617  ? 209.303 199.995 147.720 1.00 151.55 ? 628  ASN A CB  1 
ATOM   463  C CG  . ASN A 1 617  ? 210.611 199.516 148.317 1.00 151.55 ? 628  ASN A CG  1 
ATOM   464  O OD1 . ASN A 1 617  ? 211.592 200.258 148.370 1.00 151.55 ? 628  ASN A OD1 1 
ATOM   465  N ND2 . ASN A 1 617  ? 210.632 198.269 148.773 1.00 151.55 ? 628  ASN A ND2 1 
ATOM   466  N N   . VAL A 1 618  ? 206.984 202.052 147.194 1.00 148.81 ? 629  VAL A N   1 
ATOM   467  C CA  . VAL A 1 618  ? 205.756 202.440 146.507 1.00 148.81 ? 629  VAL A CA  1 
ATOM   468  C C   . VAL A 1 618  ? 205.865 203.866 145.977 1.00 148.81 ? 629  VAL A C   1 
ATOM   469  O O   . VAL A 1 618  ? 205.552 204.133 144.811 1.00 148.81 ? 629  VAL A O   1 
ATOM   470  C CB  . VAL A 1 618  ? 204.541 202.272 147.437 1.00 148.81 ? 629  VAL A CB  1 
ATOM   471  C CG1 . VAL A 1 618  ? 203.269 202.672 146.712 1.00 148.81 ? 629  VAL A CG1 1 
ATOM   472  C CG2 . VAL A 1 618  ? 204.439 200.835 147.917 1.00 148.81 ? 629  VAL A CG2 1 
ATOM   473  N N   . LEU A 1 619  ? 206.335 204.797 146.814 1.00 149.22 ? 630  LEU A N   1 
ATOM   474  C CA  . LEU A 1 619  ? 206.395 206.202 146.427 1.00 149.22 ? 630  LEU A CA  1 
ATOM   475  C C   . LEU A 1 619  ? 207.342 206.445 145.262 1.00 149.22 ? 630  LEU A C   1 
ATOM   476  O O   . LEU A 1 619  ? 207.268 207.505 144.631 1.00 149.22 ? 630  LEU A O   1 
ATOM   477  C CB  . LEU A 1 619  ? 206.819 207.056 147.623 1.00 149.22 ? 630  LEU A CB  1 
ATOM   478  C CG  . LEU A 1 619  ? 205.714 207.827 148.346 1.00 149.22 ? 630  LEU A CG  1 
ATOM   479  C CD1 . LEU A 1 619  ? 205.039 208.811 147.403 1.00 149.22 ? 630  LEU A CD1 1 
ATOM   480  C CD2 . LEU A 1 619  ? 204.697 206.869 148.947 1.00 149.22 ? 630  LEU A CD2 1 
ATOM   481  N N   . THR A 1 620  ? 208.236 205.498 144.973 1.00 152.15 ? 631  THR A N   1 
ATOM   482  C CA  . THR A 1 620  ? 209.084 205.634 143.794 1.00 152.15 ? 631  THR A CA  1 
ATOM   483  C C   . THR A 1 620  ? 208.249 205.732 142.521 1.00 152.15 ? 631  THR A C   1 
ATOM   484  O O   . THR A 1 620  ? 208.536 206.556 141.645 1.00 152.15 ? 631  THR A O   1 
ATOM   485  C CB  . THR A 1 620  ? 210.056 204.456 143.707 1.00 152.15 ? 631  THR A CB  1 
ATOM   486  O OG1 . THR A 1 620  ? 210.776 204.338 144.941 1.00 152.15 ? 631  THR A OG1 1 
ATOM   487  C CG2 . THR A 1 620  ? 211.043 204.662 142.568 1.00 152.15 ? 631  THR A CG2 1 
ATOM   488  N N   . ARG A 1 621  ? 207.211 204.906 142.402 1.00 153.82 ? 632  ARG A N   1 
ATOM   489  C CA  . ARG A 1 621  ? 206.379 204.862 141.200 1.00 153.82 ? 632  ARG A CA  1 
ATOM   490  C C   . ARG A 1 621  ? 204.896 204.819 141.568 1.00 153.82 ? 632  ARG A C   1 
ATOM   491  O O   . ARG A 1 621  ? 204.134 203.990 141.069 1.00 153.82 ? 632  ARG A O   1 
ATOM   492  C CB  . ARG A 1 621  ? 206.750 203.669 140.320 1.00 153.82 ? 632  ARG A CB  1 
ATOM   493  C CG  . ARG A 1 621  ? 208.196 203.657 139.851 1.00 153.82 ? 632  ARG A CG  1 
ATOM   494  C CD  . ARG A 1 621  ? 208.460 202.498 138.901 1.00 153.82 ? 632  ARG A CD  1 
ATOM   495  N NE  . ARG A 1 621  ? 209.855 202.436 138.480 1.00 153.82 ? 632  ARG A NE  1 
ATOM   496  C CZ  . ARG A 1 621  ? 210.422 203.276 137.625 1.00 153.82 ? 632  ARG A CZ  1 
ATOM   497  N NH1 . ARG A 1 621  ? 209.737 204.258 137.061 1.00 153.82 ? 632  ARG A NH1 1 
ATOM   498  N NH2 . ARG A 1 621  ? 211.708 203.125 137.323 1.00 153.82 ? 632  ARG A NH2 1 
ATOM   499  N N   . GLU A 1 622  ? 204.466 205.718 142.453 1.00 148.88 ? 633  GLU A N   1 
ATOM   500  C CA  . GLU A 1 622  ? 203.053 205.755 142.797 1.00 148.88 ? 633  GLU A CA  1 
ATOM   501  C C   . GLU A 1 622  ? 202.451 207.119 142.477 1.00 148.88 ? 633  GLU A C   1 
ATOM   502  O O   . GLU A 1 622  ? 203.138 208.143 142.554 1.00 148.88 ? 633  GLU A O   1 
ATOM   503  C CB  . GLU A 1 622  ? 202.822 205.436 144.281 1.00 148.88 ? 633  GLU A CB  1 
ATOM   504  C CG  . GLU A 1 622  ? 202.944 206.629 145.217 1.00 148.88 ? 633  GLU A CG  1 
ATOM   505  C CD  . GLU A 1 622  ? 202.097 206.482 146.465 1.00 148.88 ? 633  GLU A CD  1 
ATOM   506  O OE1 . GLU A 1 622  ? 201.519 205.395 146.667 1.00 148.88 ? 633  GLU A OE1 1 
ATOM   507  O OE2 . GLU A 1 622  ? 202.005 207.456 147.241 1.00 148.88 ? 633  GLU A OE2 1 
ATOM   508  N N   . PRO A 1 623  ? 201.169 207.160 142.080 1.00 149.51 ? 634  PRO A N   1 
ATOM   509  C CA  . PRO A 1 623  ? 200.458 208.430 141.893 1.00 149.51 ? 634  PRO A CA  1 
ATOM   510  C C   . PRO A 1 623  ? 199.737 208.897 143.156 1.00 149.51 ? 634  PRO A C   1 
ATOM   511  O O   . PRO A 1 623  ? 198.539 209.202 143.136 1.00 149.51 ? 634  PRO A O   1 
ATOM   512  C CB  . PRO A 1 623  ? 199.476 208.101 140.765 1.00 149.51 ? 634  PRO A CB  1 
ATOM   513  C CG  . PRO A 1 623  ? 199.153 206.651 140.983 1.00 149.51 ? 634  PRO A CG  1 
ATOM   514  C CD  . PRO A 1 623  ? 200.353 206.009 141.654 1.00 149.51 ? 634  PRO A CD  1 
ATOM   515  N N   . ALA A 1 624  ? 200.469 208.958 144.268 1.00 146.10 ? 635  ALA A N   1 
ATOM   516  C CA  . ALA A 1 624  ? 199.937 209.383 145.563 1.00 146.10 ? 635  ALA A CA  1 
ATOM   517  C C   . ALA A 1 624  ? 198.716 208.552 145.961 1.00 146.10 ? 635  ALA A C   1 
ATOM   518  O O   . ALA A 1 624  ? 197.599 209.054 146.097 1.00 146.10 ? 635  ALA A O   1 
ATOM   519  C CB  . ALA A 1 624  ? 199.610 210.879 145.555 1.00 146.10 ? 635  ALA A CB  1 
ATOM   520  N N   . ASN A 1 625  ? 198.952 207.253 146.142 1.00 142.72 ? 636  ASN A N   1 
ATOM   521  C CA  . ASN A 1 625  ? 197.883 206.346 146.541 1.00 142.72 ? 636  ASN A CA  1 
ATOM   522  C C   . ASN A 1 625  ? 197.384 206.695 147.938 1.00 142.72 ? 636  ASN A C   1 
ATOM   523  O O   . ASN A 1 625  ? 198.176 206.969 148.844 1.00 142.72 ? 636  ASN A O   1 
ATOM   524  C CB  . ASN A 1 625  ? 198.374 204.899 146.497 1.00 142.72 ? 636  ASN A CB  1 
ATOM   525  C CG  . ASN A 1 625  ? 197.247 203.893 146.645 1.00 142.72 ? 636  ASN A CG  1 
ATOM   526  O OD1 . ASN A 1 625  ? 196.618 203.796 147.699 1.00 142.72 ? 636  ASN A OD1 1 
ATOM   527  N ND2 . ASN A 1 625  ? 196.987 203.137 145.585 1.00 142.72 ? 636  ASN A ND2 1 
ATOM   528  N N   . ALA A 1 626  ? 196.059 206.684 148.107 1.00 135.32 ? 637  ALA A N   1 
ATOM   529  C CA  . ALA A 1 626  ? 195.471 207.052 149.391 1.00 135.32 ? 637  ALA A CA  1 
ATOM   530  C C   . ALA A 1 626  ? 195.843 206.057 150.483 1.00 135.32 ? 637  ALA A C   1 
ATOM   531  O O   . ALA A 1 626  ? 196.138 206.453 151.617 1.00 135.32 ? 637  ALA A O   1 
ATOM   532  C CB  . ALA A 1 626  ? 193.953 207.161 149.259 1.00 135.32 ? 637  ALA A CB  1 
ATOM   533  N N   . ASP A 1 627  ? 195.826 204.760 150.165 1.00 135.92 ? 638  ASP A N   1 
ATOM   534  C CA  . ASP A 1 627  ? 196.099 203.744 151.178 1.00 135.92 ? 638  ASP A CA  1 
ATOM   535  C C   . ASP A 1 627  ? 197.529 203.839 151.696 1.00 135.92 ? 638  ASP A C   1 
ATOM   536  O O   . ASP A 1 627  ? 197.769 203.719 152.904 1.00 135.92 ? 638  ASP A O   1 
ATOM   537  C CB  . ASP A 1 627  ? 195.823 202.352 150.610 1.00 135.92 ? 638  ASP A CB  1 
ATOM   538  C CG  . ASP A 1 627  ? 194.443 202.238 149.992 1.00 135.92 ? 638  ASP A CG  1 
ATOM   539  O OD1 . ASP A 1 627  ? 193.711 203.249 149.982 1.00 135.92 ? 638  ASP A OD1 1 
ATOM   540  O OD2 . ASP A 1 627  ? 194.091 201.138 149.518 1.00 135.92 ? 638  ASP A OD2 1 
ATOM   541  N N   . ALA A 1 628  ? 198.494 204.047 150.797 1.00 135.10 ? 639  ALA A N   1 
ATOM   542  C CA  . ALA A 1 628  ? 199.886 204.156 151.223 1.00 135.10 ? 639  ALA A CA  1 
ATOM   543  C C   . ALA A 1 628  ? 200.094 205.367 152.124 1.00 135.10 ? 639  ALA A C   1 
ATOM   544  O O   . ALA A 1 628  ? 200.772 205.275 153.155 1.00 135.10 ? 639  ALA A O   1 
ATOM   545  C CB  . ALA A 1 628  ? 200.804 204.229 150.004 1.00 135.10 ? 639  ALA A CB  1 
ATOM   546  N N   . ILE A 1 629  ? 199.511 206.503 151.733 1.00 131.38 ? 640  ILE A N   1 
ATOM   547  C CA  . ILE A 1 629  ? 199.651 207.747 152.549 1.00 131.38 ? 640  ILE A CA  1 
ATOM   548  C C   . ILE A 1 629  ? 198.993 207.509 153.918 1.00 131.38 ? 640  ILE A C   1 
ATOM   549  O O   . ILE A 1 629  ? 199.587 207.918 154.936 1.00 131.38 ? 640  ILE A O   1 
ATOM   550  C CB  . ILE A 1 629  ? 199.047 208.961 151.819 1.00 131.38 ? 640  ILE A CB  1 
ATOM   551  C CG1 . ILE A 1 629  ? 199.647 209.136 150.427 1.00 131.38 ? 640  ILE A CG1 1 
ATOM   552  C CG2 . ILE A 1 629  ? 199.205 210.230 152.654 1.00 131.38 ? 640  ILE A CG2 1 
ATOM   553  C CD1 . ILE A 1 629  ? 199.055 210.292 149.641 1.00 131.38 ? 640  ILE A CD1 1 
ATOM   554  N N   . LEU A 1 630  ? 197.823 206.863 153.938 1.00 122.59 ? 641  LEU A N   1 
ATOM   555  C CA  . LEU A 1 630  ? 197.140 206.590 155.199 1.00 122.59 ? 641  LEU A CA  1 
ATOM   556  C C   . LEU A 1 630  ? 197.984 205.695 156.101 1.00 122.59 ? 641  LEU A C   1 
ATOM   557  O O   . LEU A 1 630  ? 198.076 205.926 157.316 1.00 122.59 ? 641  LEU A O   1 
ATOM   558  C CB  . LEU A 1 630  ? 195.780 205.953 154.918 1.00 122.59 ? 641  LEU A CB  1 
ATOM   559  C CG  . LEU A 1 630  ? 194.923 205.516 156.104 1.00 122.59 ? 641  LEU A CG  1 
ATOM   560  C CD1 . LEU A 1 630  ? 194.558 206.708 156.971 1.00 122.59 ? 641  LEU A CD1 1 
ATOM   561  C CD2 . LEU A 1 630  ? 193.676 204.817 155.596 1.00 122.59 ? 641  LEU A CD2 1 
ATOM   562  N N   . GLY A 1 631  ? 198.607 204.666 155.524 1.00 126.47 ? 642  GLY A N   1 
ATOM   563  C CA  . GLY A 1 631  ? 199.533 203.852 156.293 1.00 126.47 ? 642  GLY A CA  1 
ATOM   564  C C   . GLY A 1 631  ? 200.713 204.654 156.805 1.00 126.47 ? 642  GLY A C   1 
ATOM   565  O O   . GLY A 1 631  ? 201.214 204.410 157.905 1.00 126.47 ? 642  GLY A O   1 
ATOM   566  N N   . LEU A 1 632  ? 201.175 205.622 156.010 1.00 129.52 ? 643  LEU A N   1 
ATOM   567  C CA  . LEU A 1 632  ? 202.242 206.509 156.463 1.00 129.52 ? 643  LEU A CA  1 
ATOM   568  C C   . LEU A 1 632  ? 201.801 207.336 157.665 1.00 129.52 ? 643  LEU A C   1 
ATOM   569  O O   . LEU A 1 632  ? 202.569 207.513 158.618 1.00 129.52 ? 643  LEU A O   1 
ATOM   570  C CB  . LEU A 1 632  ? 202.690 207.422 155.323 1.00 129.52 ? 643  LEU A CB  1 
ATOM   571  C CG  . LEU A 1 632  ? 203.944 206.984 154.567 1.00 129.52 ? 643  LEU A CG  1 
ATOM   572  C CD1 . LEU A 1 632  ? 205.176 207.116 155.448 1.00 129.52 ? 643  LEU A CD1 1 
ATOM   573  C CD2 . LEU A 1 632  ? 203.787 205.559 154.072 1.00 129.52 ? 643  LEU A CD2 1 
ATOM   574  N N   . THR A 1 633  ? 200.565 207.839 157.625 1.00 128.68 ? 644  THR A N   1 
ATOM   575  C CA  . THR A 1 633  ? 200.045 208.587 158.789 1.00 128.68 ? 644  THR A CA  1 
ATOM   576  C C   . THR A 1 633  ? 200.056 207.665 159.989 1.00 128.68 ? 644  THR A C   1 
ATOM   577  O O   . THR A 1 633  ? 200.575 208.080 161.047 1.00 128.68 ? 644  THR A O   1 
ATOM   578  C CB  . THR A 1 633  ? 198.643 209.126 158.509 1.00 128.68 ? 644  THR A CB  1 
ATOM   579  O OG1 . THR A 1 633  ? 197.781 207.992 158.495 1.00 128.68 ? 644  THR A OG1 1 
ATOM   580  C CG2 . THR A 1 633  ? 198.555 209.872 157.191 1.00 128.68 ? 644  THR A CG2 1 
ATOM   581  N N   . GLU A 1 634  ? 199.516 206.452 159.838 1.00 126.22 ? 645  GLU A N   1 
ATOM   582  C CA  . GLU A 1 634  ? 199.434 205.530 160.968 1.00 126.22 ? 645  GLU A CA  1 
ATOM   583  C C   . GLU A 1 634  ? 200.815 205.224 161.537 1.00 126.22 ? 645  GLU A C   1 
ATOM   584  O O   . GLU A 1 634  ? 200.995 205.176 162.760 1.00 126.22 ? 645  GLU A O   1 
ATOM   585  C CB  . GLU A 1 634  ? 198.726 204.243 160.545 1.00 126.22 ? 645  GLU A CB  1 
ATOM   586  C CG  . GLU A 1 634  ? 197.267 204.442 160.177 1.00 126.22 ? 645  GLU A CG  1 
ATOM   587  C CD  . GLU A 1 634  ? 196.458 205.047 161.308 1.00 126.22 ? 645  GLU A CD  1 
ATOM   588  O OE1 . GLU A 1 634  ? 196.645 204.622 162.468 1.00 126.22 ? 645  GLU A OE1 1 
ATOM   589  O OE2 . GLU A 1 634  ? 195.637 205.949 161.039 1.00 126.22 ? 645  GLU A OE2 1 
ATOM   590  N N   . VAL A 1 635  ? 201.804 205.020 160.664 1.00 128.73 ? 646  VAL A N   1 
ATOM   591  C CA  . VAL A 1 635  ? 203.164 204.745 161.122 1.00 128.73 ? 646  VAL A CA  1 
ATOM   592  C C   . VAL A 1 635  ? 203.731 205.949 161.864 1.00 128.73 ? 646  VAL A C   1 
ATOM   593  O O   . VAL A 1 635  ? 204.360 205.807 162.920 1.00 128.73 ? 646  VAL A O   1 
ATOM   594  C CB  . VAL A 1 635  ? 204.054 204.337 159.933 1.00 128.73 ? 646  VAL A CB  1 
ATOM   595  C CG1 . VAL A 1 635  ? 205.527 204.450 160.299 1.00 128.73 ? 646  VAL A CG1 1 
ATOM   596  C CG2 . VAL A 1 635  ? 203.719 202.923 159.482 1.00 128.73 ? 646  VAL A CG2 1 
ATOM   597  N N   . ASP A 1 636  ? 203.514 207.154 161.328 1.00 131.67 ? 647  ASP A N   1 
ATOM   598  C CA  . ASP A 1 636  ? 204.015 208.359 161.981 1.00 131.67 ? 647  ASP A CA  1 
ATOM   599  C C   . ASP A 1 636  ? 203.374 208.554 163.349 1.00 131.67 ? 647  ASP A C   1 
ATOM   600  O O   . ASP A 1 636  ? 204.047 208.955 164.306 1.00 131.67 ? 647  ASP A O   1 
ATOM   601  C CB  . ASP A 1 636  ? 203.769 209.578 161.092 1.00 131.67 ? 647  ASP A CB  1 
ATOM   602  C CG  . ASP A 1 636  ? 204.623 209.567 159.840 1.00 131.67 ? 647  ASP A CG  1 
ATOM   603  O OD1 . ASP A 1 636  ? 205.400 208.607 159.657 1.00 131.67 ? 647  ASP A OD1 1 
ATOM   604  O OD2 . ASP A 1 636  ? 204.518 210.520 159.039 1.00 131.67 ? 647  ASP A OD2 1 
ATOM   605  N N   . ILE A 1 637  ? 202.071 208.285 163.460 1.00 129.04 ? 648  ILE A N   1 
ATOM   606  C CA  . ILE A 1 637  ? 201.409 208.357 164.760 1.00 129.04 ? 648  ILE A CA  1 
ATOM   607  C C   . ILE A 1 637  ? 201.999 207.325 165.712 1.00 129.04 ? 648  ILE A C   1 
ATOM   608  O O   . ILE A 1 637  ? 202.245 207.614 166.890 1.00 129.04 ? 648  ILE A O   1 
ATOM   609  C CB  . ILE A 1 637  ? 199.887 208.181 164.599 1.00 129.04 ? 648  ILE A CB  1 
ATOM   610  C CG1 . ILE A 1 637  ? 199.293 209.364 163.833 1.00 129.04 ? 648  ILE A CG1 1 
ATOM   611  C CG2 . ILE A 1 637  ? 199.217 208.038 165.957 1.00 129.04 ? 648  ILE A CG2 1 
ATOM   612  C CD1 . ILE A 1 637  ? 197.822 209.213 163.523 1.00 129.04 ? 648  ILE A CD1 1 
ATOM   613  N N   . ALA A 1 638  ? 202.238 206.107 165.220 1.00 130.35 ? 649  ALA A N   1 
ATOM   614  C CA  . ALA A 1 638  ? 202.895 205.096 166.041 1.00 130.35 ? 649  ALA A CA  1 
ATOM   615  C C   . ALA A 1 638  ? 204.307 205.526 166.417 1.00 130.35 ? 649  ALA A C   1 
ATOM   616  O O   . ALA A 1 638  ? 204.742 205.330 167.559 1.00 130.35 ? 649  ALA A O   1 
ATOM   617  C CB  . ALA A 1 638  ? 202.917 203.755 165.308 1.00 130.35 ? 649  ALA A CB  1 
ATOM   618  N N   . ALA A 1 639  ? 205.042 206.111 165.467 1.00 131.90 ? 650  ALA A N   1 
ATOM   619  C CA  . ALA A 1 639  ? 206.382 206.606 165.762 1.00 131.90 ? 650  ALA A CA  1 
ATOM   620  C C   . ALA A 1 639  ? 206.352 207.762 166.754 1.00 131.90 ? 650  ALA A C   1 
ATOM   621  O O   . ALA A 1 639  ? 207.214 207.841 167.637 1.00 131.90 ? 650  ALA A O   1 
ATOM   622  C CB  . ALA A 1 639  ? 207.083 207.031 164.472 1.00 131.90 ? 650  ALA A CB  1 
ATOM   623  N N   . GLY A 1 640  ? 205.378 208.660 166.629 1.00 130.73 ? 651  GLY A N   1 
ATOM   624  C CA  . GLY A 1 640  ? 205.268 209.787 167.533 1.00 130.73 ? 651  GLY A CA  1 
ATOM   625  C C   . GLY A 1 640  ? 205.738 211.098 166.937 1.00 130.73 ? 651  GLY A C   1 
ATOM   626  O O   . GLY A 1 640  ? 206.411 211.886 167.607 1.00 130.73 ? 651  GLY A O   1 
ATOM   627  N N   . ASP A 1 641  ? 205.389 211.343 165.676 1.00 127.07 ? 652  ASP A N   1 
ATOM   628  C CA  . ASP A 1 641  ? 205.730 212.582 164.979 1.00 127.07 ? 652  ASP A CA  1 
ATOM   629  C C   . ASP A 1 641  ? 204.425 213.267 164.586 1.00 127.07 ? 652  ASP A C   1 
ATOM   630  O O   . ASP A 1 641  ? 203.820 212.926 163.565 1.00 127.07 ? 652  ASP A O   1 
ATOM   631  C CB  . ASP A 1 641  ? 206.608 212.305 163.761 1.00 127.07 ? 652  ASP A CB  1 
ATOM   632  C CG  . ASP A 1 641  ? 207.344 213.540 163.280 1.00 127.07 ? 652  ASP A CG  1 
ATOM   633  O OD1 . ASP A 1 641  ? 207.012 214.652 163.742 1.00 127.07 ? 652  ASP A OD1 1 
ATOM   634  O OD2 . ASP A 1 641  ? 208.257 213.399 162.440 1.00 127.07 ? 652  ASP A OD2 1 
ATOM   635  N N   . LYS A 1 642  ? 203.993 214.231 165.403 1.00 126.60 ? 653  LYS A N   1 
ATOM   636  C CA  . LYS A 1 642  ? 202.723 214.906 165.152 1.00 126.60 ? 653  LYS A CA  1 
ATOM   637  C C   . LYS A 1 642  ? 202.760 215.705 163.854 1.00 126.60 ? 653  LYS A C   1 
ATOM   638  O O   . LYS A 1 642  ? 201.801 215.674 163.074 1.00 126.60 ? 653  LYS A O   1 
ATOM   639  C CB  . LYS A 1 642  ? 202.372 215.811 166.334 1.00 126.60 ? 653  LYS A CB  1 
ATOM   640  C CG  . LYS A 1 642  ? 200.987 216.440 166.261 1.00 126.60 ? 653  LYS A CG  1 
ATOM   641  C CD  . LYS A 1 642  ? 201.049 217.887 165.794 1.00 126.60 ? 653  LYS A CD  1 
ATOM   642  C CE  . LYS A 1 642  ? 199.697 218.570 165.928 1.00 126.60 ? 653  LYS A CE  1 
ATOM   643  N NZ  . LYS A 1 642  ? 198.647 217.888 165.123 1.00 126.60 ? 653  LYS A NZ  1 
ATOM   644  N N   . ALA A 1 643  ? 203.856 216.425 163.604 1.00 126.16 ? 654  ALA A N   1 
ATOM   645  C CA  . ALA A 1 643  ? 203.932 217.278 162.421 1.00 126.16 ? 654  ALA A CA  1 
ATOM   646  C C   . ALA A 1 643  ? 203.939 216.452 161.140 1.00 126.16 ? 654  ALA A C   1 
ATOM   647  O O   . ALA A 1 643  ? 203.215 216.761 160.185 1.00 126.16 ? 654  ALA A O   1 
ATOM   648  C CB  . ALA A 1 643  ? 205.172 218.169 162.496 1.00 126.16 ? 654  ALA A CB  1 
ATOM   649  N N   . ALA A 1 644  ? 204.759 215.398 161.097 1.00 126.33 ? 655  ALA A N   1 
ATOM   650  C CA  . ALA A 1 644  ? 204.820 214.558 159.905 1.00 126.33 ? 655  ALA A CA  1 
ATOM   651  C C   . ALA A 1 644  ? 203.493 213.852 159.661 1.00 126.33 ? 655  ALA A C   1 
ATOM   652  O O   . ALA A 1 644  ? 203.034 213.755 158.516 1.00 126.33 ? 655  ALA A O   1 
ATOM   653  C CB  . ALA A 1 644  ? 205.954 213.543 160.034 1.00 126.33 ? 655  ALA A CB  1 
ATOM   654  N N   . ALA A 1 645  ? 202.863 213.350 160.726 1.00 128.74 ? 656  ALA A N   1 
ATOM   655  C CA  . ALA A 1 645  ? 201.569 212.694 160.578 1.00 128.74 ? 656  ALA A CA  1 
ATOM   656  C C   . ALA A 1 645  ? 200.511 213.668 160.076 1.00 128.74 ? 656  ALA A C   1 
ATOM   657  O O   . ALA A 1 645  ? 199.694 213.319 159.217 1.00 128.74 ? 656  ALA A O   1 
ATOM   658  C CB  . ALA A 1 645  ? 201.141 212.068 161.905 1.00 128.74 ? 656  ALA A CB  1 
ATOM   659  N N   . ARG A 1 646  ? 200.510 214.896 160.602 1.00 128.09 ? 657  ARG A N   1 
ATOM   660  C CA  . ARG A 1 646  ? 199.557 215.899 160.138 1.00 128.09 ? 657  ARG A CA  1 
ATOM   661  C C   . ARG A 1 646  ? 199.789 216.246 158.673 1.00 128.09 ? 657  ARG A C   1 
ATOM   662  O O   . ARG A 1 646  ? 198.833 216.394 157.903 1.00 128.09 ? 657  ARG A O   1 
ATOM   663  C CB  . ARG A 1 646  ? 199.647 217.152 161.008 1.00 128.09 ? 657  ARG A CB  1 
ATOM   664  C CG  . ARG A 1 646  ? 198.481 218.113 160.838 1.00 128.09 ? 657  ARG A CG  1 
ATOM   665  C CD  . ARG A 1 646  ? 197.153 217.423 161.104 1.00 128.09 ? 657  ARG A CD  1 
ATOM   666  N NE  . ARG A 1 646  ? 196.040 218.116 160.467 1.00 128.09 ? 657  ARG A NE  1 
ATOM   667  C CZ  . ARG A 1 646  ? 195.610 217.871 159.236 1.00 128.09 ? 657  ARG A CZ  1 
ATOM   668  N NH1 . ARG A 1 646  ? 196.180 216.951 158.476 1.00 128.09 ? 657  ARG A NH1 1 
ATOM   669  N NH2 . ARG A 1 646  ? 194.583 218.567 158.757 1.00 128.09 ? 657  ARG A NH2 1 
ATOM   670  N N   . SER A 1 647  ? 201.055 216.383 158.269 1.00 128.76 ? 658  SER A N   1 
ATOM   671  C CA  . SER A 1 647  ? 201.357 216.683 156.872 1.00 128.76 ? 658  SER A CA  1 
ATOM   672  C C   . SER A 1 647  ? 200.901 215.552 155.958 1.00 128.76 ? 658  SER A C   1 
ATOM   673  O O   . SER A 1 647  ? 200.310 215.792 154.898 1.00 128.76 ? 658  SER A O   1 
ATOM   674  C CB  . SER A 1 647  ? 202.855 216.942 156.706 1.00 128.76 ? 658  SER A CB  1 
ATOM   675  O OG  . SER A 1 647  ? 203.192 217.120 155.341 1.00 128.76 ? 658  SER A OG  1 
ATOM   676  N N   . GLN A 1 648  ? 201.159 214.305 156.360 1.00 131.26 ? 659  GLN A N   1 
ATOM   677  C CA  . GLN A 1 648  ? 200.731 213.168 155.552 1.00 131.26 ? 659  GLN A CA  1 
ATOM   678  C C   . GLN A 1 648  ? 199.210 213.088 155.472 1.00 131.26 ? 659  GLN A C   1 
ATOM   679  O O   . GLN A 1 648  ? 198.654 212.770 154.415 1.00 131.26 ? 659  GLN A O   1 
ATOM   680  C CB  . GLN A 1 648  ? 201.315 211.873 156.115 1.00 131.26 ? 659  GLN A CB  1 
ATOM   681  C CG  . GLN A 1 648  ? 202.829 211.773 156.017 1.00 131.26 ? 659  GLN A CG  1 
ATOM   682  C CD  . GLN A 1 648  ? 203.312 211.593 154.591 1.00 131.26 ? 659  GLN A CD  1 
ATOM   683  O OE1 . GLN A 1 648  ? 202.570 211.129 153.726 1.00 131.26 ? 659  GLN A OE1 1 
ATOM   684  N NE2 . GLN A 1 648  ? 204.563 211.959 154.339 1.00 131.26 ? 659  GLN A NE2 1 
ATOM   685  N N   . LEU A 1 649  ? 198.520 213.373 156.580 1.00 126.56 ? 660  LEU A N   1 
ATOM   686  C CA  . LEU A 1 649  ? 197.061 213.391 156.556 1.00 126.56 ? 660  LEU A CA  1 
ATOM   687  C C   . LEU A 1 649  ? 196.540 214.479 155.627 1.00 126.56 ? 660  LEU A C   1 
ATOM   688  O O   . LEU A 1 649  ? 195.556 214.274 154.907 1.00 126.56 ? 660  LEU A O   1 
ATOM   689  C CB  . LEU A 1 649  ? 196.513 213.582 157.970 1.00 126.56 ? 660  LEU A CB  1 
ATOM   690  C CG  . LEU A 1 649  ? 195.870 212.355 158.621 1.00 126.56 ? 660  LEU A CG  1 
ATOM   691  C CD1 . LEU A 1 649  ? 194.982 212.768 159.783 1.00 126.56 ? 660  LEU A CD1 1 
ATOM   692  C CD2 . LEU A 1 649  ? 195.079 211.551 157.599 1.00 126.56 ? 660  LEU A CD2 1 
ATOM   693  N N   . ALA A 1 650  ? 197.184 215.649 155.636 1.00 127.95 ? 661  ALA A N   1 
ATOM   694  C CA  . ALA A 1 650  ? 196.818 216.701 154.694 1.00 127.95 ? 661  ALA A CA  1 
ATOM   695  C C   . ALA A 1 650  ? 197.110 216.288 153.257 1.00 127.95 ? 661  ALA A C   1 
ATOM   696  O O   . ALA A 1 650  ? 196.455 216.775 152.328 1.00 127.95 ? 661  ALA A O   1 
ATOM   697  C CB  . ALA A 1 650  ? 197.554 217.995 155.036 1.00 127.95 ? 661  ALA A CB  1 
ATOM   698  N N   . LYS A 1 651  ? 198.082 215.397 153.055 1.00 127.48 ? 662  LYS A N   1 
ATOM   699  C CA  . LYS A 1 651  ? 198.393 214.899 151.720 1.00 127.48 ? 662  LYS A CA  1 
ATOM   700  C C   . LYS A 1 651  ? 197.324 213.963 151.168 1.00 127.48 ? 662  LYS A C   1 
ATOM   701  O O   . LYS A 1 651  ? 197.401 213.599 149.989 1.00 127.48 ? 662  LYS A O   1 
ATOM   702  C CB  . LYS A 1 651  ? 199.747 214.186 151.724 1.00 127.48 ? 662  LYS A CB  1 
ATOM   703  C CG  . LYS A 1 651  ? 200.868 214.976 151.069 1.00 127.48 ? 662  LYS A CG  1 
ATOM   704  C CD  . LYS A 1 651  ? 201.172 216.253 151.833 1.00 127.48 ? 662  LYS A CD  1 
ATOM   705  C CE  . LYS A 1 651  ? 201.910 217.255 150.962 1.00 127.48 ? 662  LYS A CE  1 
ATOM   706  N NZ  . LYS A 1 651  ? 201.911 218.617 151.563 1.00 127.48 ? 662  LYS A NZ  1 
ATOM   707  N N   . LEU A 1 652  ? 196.350 213.561 151.979 1.00 130.23 ? 663  LEU A N   1 
ATOM   708  C CA  . LEU A 1 652  ? 195.295 212.685 151.493 1.00 130.23 ? 663  LEU A CA  1 
ATOM   709  C C   . LEU A 1 652  ? 194.492 213.389 150.401 1.00 130.23 ? 663  LEU A C   1 
ATOM   710  O O   . LEU A 1 652  ? 194.271 214.604 150.478 1.00 130.23 ? 663  LEU A O   1 
ATOM   711  C CB  . LEU A 1 652  ? 194.366 212.270 152.636 1.00 130.23 ? 663  LEU A CB  1 
ATOM   712  C CG  . LEU A 1 652  ? 194.616 210.930 153.334 1.00 130.23 ? 663  LEU A CG  1 
ATOM   713  C CD1 . LEU A 1 652  ? 194.418 209.767 152.372 1.00 130.23 ? 663  LEU A CD1 1 
ATOM   714  C CD2 . LEU A 1 652  ? 195.998 210.884 153.964 1.00 130.23 ? 663  LEU A CD2 1 
ATOM   715  N N   . PRO A 1 653  ? 194.048 212.667 149.374 1.00 133.92 ? 664  PRO A N   1 
ATOM   716  C CA  . PRO A 1 653  ? 193.252 213.295 148.312 1.00 133.92 ? 664  PRO A CA  1 
ATOM   717  C C   . PRO A 1 653  ? 191.895 213.755 148.824 1.00 133.92 ? 664  PRO A C   1 
ATOM   718  O O   . PRO A 1 653  ? 191.532 213.576 149.989 1.00 133.92 ? 664  PRO A O   1 
ATOM   719  C CB  . PRO A 1 653  ? 193.107 212.182 147.267 1.00 133.92 ? 664  PRO A CB  1 
ATOM   720  C CG  . PRO A 1 653  ? 194.220 211.225 147.565 1.00 133.92 ? 664  PRO A CG  1 
ATOM   721  C CD  . PRO A 1 653  ? 194.397 211.274 149.051 1.00 133.92 ? 664  PRO A CD  1 
ATOM   722  N N   . ALA A 1 654  ? 191.134 214.364 147.918 1.00 134.73 ? 665  ALA A N   1 
ATOM   723  C CA  . ALA A 1 654  ? 189.811 214.867 148.263 1.00 134.73 ? 665  ALA A CA  1 
ATOM   724  C C   . ALA A 1 654  ? 188.875 213.719 148.617 1.00 134.73 ? 665  ALA A C   1 
ATOM   725  O O   . ALA A 1 654  ? 189.001 212.607 148.095 1.00 134.73 ? 665  ALA A O   1 
ATOM   726  C CB  . ALA A 1 654  ? 189.235 215.681 147.105 1.00 134.73 ? 665  ALA A CB  1 
ATOM   727  N N   . THR A 1 655  ? 187.934 213.995 149.518 1.00 134.44 ? 666  THR A N   1 
ATOM   728  C CA  . THR A 1 655  ? 186.987 212.977 149.951 1.00 134.44 ? 666  THR A CA  1 
ATOM   729  C C   . THR A 1 655  ? 186.107 212.527 148.789 1.00 134.44 ? 666  THR A C   1 
ATOM   730  O O   . THR A 1 655  ? 185.745 213.313 147.909 1.00 134.44 ? 666  THR A O   1 
ATOM   731  C CB  . THR A 1 655  ? 186.119 213.506 151.094 1.00 134.44 ? 666  THR A CB  1 
ATOM   732  O OG1 . THR A 1 655  ? 185.400 214.665 150.655 1.00 134.44 ? 666  THR A OG1 1 
ATOM   733  C CG2 . THR A 1 655  ? 186.983 213.874 152.292 1.00 134.44 ? 666  THR A CG2 1 
ATOM   734  N N   . ASP A 1 656  ? 185.765 211.245 148.798 1.00 122.56 ? 667  ASP A N   1 
ATOM   735  C CA  . ASP A 1 656  ? 184.995 210.620 147.728 1.00 122.56 ? 667  ASP A CA  1 
ATOM   736  C C   . ASP A 1 656  ? 184.148 209.517 148.354 1.00 122.56 ? 667  ASP A C   1 
ATOM   737  O O   . ASP A 1 656  ? 183.889 209.535 149.562 1.00 122.56 ? 667  ASP A O   1 
ATOM   738  C CB  . ASP A 1 656  ? 185.930 210.113 146.617 1.00 122.56 ? 667  ASP A CB  1 
ATOM   739  C CG  . ASP A 1 656  ? 185.254 210.074 145.260 1.00 122.56 ? 667  ASP A CG  1 
ATOM   740  O OD1 . ASP A 1 656  ? 184.069 210.461 145.175 1.00 122.56 ? 667  ASP A OD1 1 
ATOM   741  O OD2 . ASP A 1 656  ? 185.906 209.658 144.280 1.00 122.56 ? 667  ASP A OD2 1 
ATOM   742  N N   . ASN A 1 657  ? 183.678 208.580 147.522 1.00 112.03 ? 668  ASN A N   1 
ATOM   743  C CA  . ASN A 1 657  ? 182.944 207.416 148.008 1.00 112.03 ? 668  ASN A CA  1 
ATOM   744  C C   . ASN A 1 657  ? 183.629 206.802 149.224 1.00 112.03 ? 668  ASN A C   1 
ATOM   745  O O   . ASN A 1 657  ? 183.043 206.734 150.311 1.00 112.03 ? 668  ASN A O   1 
ATOM   746  C CB  . ASN A 1 657  ? 182.800 206.383 146.886 1.00 112.03 ? 668  ASN A CB  1 
ATOM   747  C CG  . ASN A 1 657  ? 181.567 206.616 146.036 1.00 112.03 ? 668  ASN A CG  1 
ATOM   748  O OD1 . ASN A 1 657  ? 181.637 207.236 144.975 1.00 112.03 ? 668  ASN A OD1 1 
ATOM   749  N ND2 . ASN A 1 657  ? 180.426 206.120 146.501 1.00 112.03 ? 668  ASN A ND2 1 
ATOM   750  N N   . ALA A 1 658  ? 184.878 206.366 149.053 1.00 99.76  ? 669  ALA A N   1 
ATOM   751  C CA  . ALA A 1 658  ? 185.783 206.073 150.165 1.00 99.76  ? 669  ALA A CA  1 
ATOM   752  C C   . ALA A 1 658  ? 185.134 205.130 151.183 1.00 99.76  ? 669  ALA A C   1 
ATOM   753  O O   . ALA A 1 658  ? 184.757 205.528 152.284 1.00 99.76  ? 669  ALA A O   1 
ATOM   754  C CB  . ALA A 1 658  ? 186.253 207.370 150.829 1.00 99.76  ? 669  ALA A CB  1 
ATOM   755  N N   . SER A 1 659  ? 184.966 203.878 150.744 1.00 90.70  ? 670  SER A N   1 
ATOM   756  C CA  . SER A 1 659  ? 184.321 202.836 151.540 1.00 90.70  ? 670  SER A CA  1 
ATOM   757  C C   . SER A 1 659  ? 184.698 202.944 153.013 1.00 90.70  ? 670  SER A C   1 
ATOM   758  O O   . SER A 1 659  ? 185.862 203.157 153.359 1.00 90.70  ? 670  SER A O   1 
ATOM   759  C CB  . SER A 1 659  ? 184.705 201.454 151.004 1.00 90.70  ? 670  SER A CB  1 
ATOM   760  O OG  . SER A 1 659  ? 184.813 201.466 149.591 1.00 90.70  ? 670  SER A OG  1 
ATOM   761  N N   . LEU A 1 660  ? 183.689 202.768 153.873 1.00 85.19  ? 671  LEU A N   1 
ATOM   762  C CA  . LEU A 1 660  ? 183.717 203.237 155.258 1.00 85.19  ? 671  LEU A CA  1 
ATOM   763  C C   . LEU A 1 660  ? 185.014 202.927 156.000 1.00 85.19  ? 671  LEU A C   1 
ATOM   764  O O   . LEU A 1 660  ? 185.348 203.637 156.956 1.00 85.19  ? 671  LEU A O   1 
ATOM   765  C CB  . LEU A 1 660  ? 182.536 202.628 156.018 1.00 85.19  ? 671  LEU A CB  1 
ATOM   766  C CG  . LEU A 1 660  ? 181.140 202.983 155.502 1.00 85.19  ? 671  LEU A CG  1 
ATOM   767  C CD1 . LEU A 1 660  ? 180.263 201.743 155.484 1.00 85.19  ? 671  LEU A CD1 1 
ATOM   768  C CD2 . LEU A 1 660  ? 180.500 204.077 156.340 1.00 85.19  ? 671  LEU A CD2 1 
ATOM   769  N N   . ASN A 1 661  ? 185.730 201.884 155.576 1.00 83.79  ? 672  ASN A N   1 
ATOM   770  C CA  . ASN A 1 661  ? 186.963 201.472 156.303 1.00 83.79  ? 672  ASN A CA  1 
ATOM   771  C C   . ASN A 1 661  ? 187.986 202.611 156.279 1.00 83.79  ? 672  ASN A C   1 
ATOM   772  O O   . ASN A 1 661  ? 188.440 203.010 157.372 1.00 83.79  ? 672  ASN A O   1 
ATOM   773  C CB  . ASN A 1 661  ? 187.533 200.175 155.738 1.00 83.79  ? 672  ASN A CB  1 
ATOM   774  C CG  . ASN A 1 661  ? 188.461 199.483 156.708 1.00 83.79  ? 672  ASN A CG  1 
ATOM   775  O OD1 . ASN A 1 661  ? 189.505 200.038 157.069 1.00 83.79  ? 672  ASN A OD1 1 
ATOM   776  N ND2 . ASN A 1 661  ? 188.109 198.279 157.136 1.00 83.79  ? 672  ASN A ND2 1 
ATOM   777  N N   . THR A 1 662  ? 188.323 203.128 155.094 1.00 87.50  ? 673  THR A N   1 
ATOM   778  C CA  . THR A 1 662  ? 189.368 204.142 154.987 1.00 87.50  ? 673  THR A CA  1 
ATOM   779  C C   . THR A 1 662  ? 188.950 205.441 155.665 1.00 87.50  ? 673  THR A C   1 
ATOM   780  O O   . THR A 1 662  ? 189.780 206.126 156.275 1.00 87.50  ? 673  THR A O   1 
ATOM   781  C CB  . THR A 1 662  ? 189.736 204.386 153.521 1.00 87.50  ? 673  THR A CB  1 
ATOM   782  O OG1 . THR A 1 662  ? 190.650 205.486 153.433 1.00 87.50  ? 673  THR A OG1 1 
ATOM   783  C CG2 . THR A 1 662  ? 188.503 204.693 152.687 1.00 87.50  ? 673  THR A CG2 1 
ATOM   784  N N   . GLN A 1 663  ? 187.658 205.765 155.578 1.00 86.45  ? 674  GLN A N   1 
ATOM   785  C CA  . GLN A 1 663  ? 187.152 206.977 156.269 1.00 86.45  ? 674  GLN A CA  1 
ATOM   786  C C   . GLN A 1 663  ? 187.356 206.788 157.775 1.00 86.45  ? 674  GLN A C   1 
ATOM   787  O O   . GLN A 1 663  ? 187.834 207.731 158.435 1.00 86.45  ? 674  GLN A O   1 
ATOM   788  C CB  . GLN A 1 663  ? 185.672 207.208 155.977 1.00 86.45  ? 674  GLN A CB  1 
ATOM   789  C CG  . GLN A 1 663  ? 185.383 207.746 154.582 1.00 86.45  ? 674  GLN A CG  1 
ATOM   790  C CD  . GLN A 1 663  ? 183.906 207.958 154.338 1.00 86.45  ? 674  GLN A CD  1 
ATOM   791  O OE1 . GLN A 1 663  ? 183.223 208.643 155.106 1.00 86.45  ? 674  GLN A OE1 1 
ATOM   792  N NE2 . GLN A 1 663  ? 183.389 207.350 153.281 1.00 86.45  ? 674  GLN A NE2 1 
ATOM   793  N N   . ARG A 1 664  ? 187.015 205.605 158.287 1.00 82.61  ? 675  ARG A N   1 
ATOM   794  C CA  . ARG A 1 664  ? 187.198 205.342 159.711 1.00 82.61  ? 675  ARG A CA  1 
ATOM   795  C C   . ARG A 1 664  ? 188.659 205.488 160.114 1.00 82.61  ? 675  ARG A C   1 
ATOM   796  O O   . ARG A 1 664  ? 188.965 206.069 161.162 1.00 82.61  ? 675  ARG A O   1 
ATOM   797  C CB  . ARG A 1 664  ? 186.689 203.945 160.063 1.00 82.61  ? 675  ARG A CB  1 
ATOM   798  C CG  . ARG A 1 664  ? 186.694 203.656 161.556 1.00 82.61  ? 675  ARG A CG  1 
ATOM   799  C CD  . ARG A 1 664  ? 186.524 202.174 161.849 1.00 82.61  ? 675  ARG A CD  1 
ATOM   800  N NE  . ARG A 1 664  ? 187.727 201.410 161.542 1.00 82.61  ? 675  ARG A NE  1 
ATOM   801  C CZ  . ARG A 1 664  ? 187.865 200.625 160.483 1.00 82.61  ? 675  ARG A CZ  1 
ATOM   802  N NH1 . ARG A 1 664  ? 186.891 200.477 159.601 1.00 82.61  ? 675  ARG A NH1 1 
ATOM   803  N NH2 . ARG A 1 664  ? 189.009 199.971 160.305 1.00 82.61  ? 675  ARG A NH2 1 
ATOM   804  N N   . ARG A 1 665  ? 189.575 204.961 159.298 1.00 89.30  ? 676  ARG A N   1 
ATOM   805  C CA  . ARG A 1 665  ? 190.996 205.092 159.617 1.00 89.30  ? 676  ARG A CA  1 
ATOM   806  C C   . ARG A 1 665  ? 191.431 206.554 159.622 1.00 89.30  ? 676  ARG A C   1 
ATOM   807  O O   . ARG A 1 665  ? 192.182 206.982 160.507 1.00 89.30  ? 676  ARG A O   1 
ATOM   808  C CB  . ARG A 1 665  ? 191.847 204.289 158.633 1.00 89.30  ? 676  ARG A CB  1 
ATOM   809  C CG  . ARG A 1 665  ? 191.356 202.881 158.379 1.00 89.30  ? 676  ARG A CG  1 
ATOM   810  C CD  . ARG A 1 665  ? 192.430 202.014 157.746 1.00 89.30  ? 676  ARG A CD  1 
ATOM   811  N NE  . ARG A 1 665  ? 193.583 201.833 158.620 1.00 89.30  ? 676  ARG A NE  1 
ATOM   812  C CZ  . ARG A 1 665  ? 194.845 201.903 158.219 1.00 89.30  ? 676  ARG A CZ  1 
ATOM   813  N NH1 . ARG A 1 665  ? 195.157 202.156 156.959 1.00 89.30  ? 676  ARG A NH1 1 
ATOM   814  N NH2 . ARG A 1 665  ? 195.818 201.708 159.104 1.00 89.30  ? 676  ARG A NH2 1 
ATOM   815  N N   . VAL A 1 666  ? 190.972 207.333 158.640 1.00 92.69  ? 677  VAL A N   1 
ATOM   816  C CA  . VAL A 1 666  ? 191.327 208.750 158.583 1.00 92.69  ? 677  VAL A CA  1 
ATOM   817  C C   . VAL A 1 666  ? 190.771 209.491 159.792 1.00 92.69  ? 677  VAL A C   1 
ATOM   818  O O   . VAL A 1 666  ? 191.451 210.336 160.389 1.00 92.69  ? 677  VAL A O   1 
ATOM   819  C CB  . VAL A 1 666  ? 190.841 209.373 157.261 1.00 92.69  ? 677  VAL A CB  1 
ATOM   820  C CG1 . VAL A 1 666  ? 191.055 210.878 157.272 1.00 92.69  ? 677  VAL A CG1 1 
ATOM   821  C CG2 . VAL A 1 666  ? 191.570 208.749 156.084 1.00 92.69  ? 677  VAL A CG2 1 
ATOM   822  N N   . ALA A 1 667  ? 189.525 209.194 160.169 1.00 95.78  ? 678  ALA A N   1 
ATOM   823  C CA  . ALA A 1 667  ? 188.930 209.842 161.333 1.00 95.78  ? 678  ALA A CA  1 
ATOM   824  C C   . ALA A 1 667  ? 189.681 209.485 162.610 1.00 95.78  ? 678  ALA A C   1 
ATOM   825  O O   . ALA A 1 667  ? 189.905 210.346 163.467 1.00 95.78  ? 678  ALA A O   1 
ATOM   826  C CB  . ALA A 1 667  ? 187.455 209.462 161.448 1.00 95.78  ? 678  ALA A CB  1 
ATOM   827  N N   . LEU A 1 668  ? 190.082 208.219 162.754 1.00 95.70  ? 679  LEU A N   1 
ATOM   828  C CA  . LEU A 1 668  ? 190.874 207.826 163.917 1.00 95.70  ? 679  LEU A CA  1 
ATOM   829  C C   . LEU A 1 668  ? 192.210 208.557 163.945 1.00 95.70  ? 679  LEU A C   1 
ATOM   830  O O   . LEU A 1 668  ? 192.632 209.059 164.995 1.00 95.70  ? 679  LEU A O   1 
ATOM   831  C CB  . LEU A 1 668  ? 191.095 206.314 163.920 1.00 95.70  ? 679  LEU A CB  1 
ATOM   832  C CG  . LEU A 1 668  ? 189.880 205.419 164.166 1.00 95.70  ? 679  LEU A CG  1 
ATOM   833  C CD1 . LEU A 1 668  ? 190.245 203.962 163.933 1.00 95.70  ? 679  LEU A CD1 1 
ATOM   834  C CD2 . LEU A 1 668  ? 189.334 205.622 165.570 1.00 95.70  ? 679  LEU A CD2 1 
ATOM   835  N N   . ALA A 1 669  ? 192.886 208.635 162.795 1.00 106.52 ? 680  ALA A N   1 
ATOM   836  C CA  . ALA A 1 669  ? 194.165 209.333 162.733 1.00 106.52 ? 680  ALA A CA  1 
ATOM   837  C C   . ALA A 1 669  ? 194.006 210.800 163.107 1.00 106.52 ? 680  ALA A C   1 
ATOM   838  O O   . ALA A 1 669  ? 194.847 211.363 163.816 1.00 106.52 ? 680  ALA A O   1 
ATOM   839  C CB  . ALA A 1 669  ? 194.774 209.194 161.338 1.00 106.52 ? 680  ALA A CB  1 
ATOM   840  N N   . GLN A 1 670  ? 192.929 211.435 162.639 1.00 105.22 ? 681  GLN A N   1 
ATOM   841  C CA  . GLN A 1 670  ? 192.642 212.806 163.047 1.00 105.22 ? 681  GLN A CA  1 
ATOM   842  C C   . GLN A 1 670  ? 192.383 212.889 164.546 1.00 105.22 ? 681  GLN A C   1 
ATOM   843  O O   . GLN A 1 670  ? 192.777 213.862 165.200 1.00 105.22 ? 681  GLN A O   1 
ATOM   844  C CB  . GLN A 1 670  ? 191.445 213.346 162.265 1.00 105.22 ? 681  GLN A CB  1 
ATOM   845  C CG  . GLN A 1 670  ? 191.816 214.138 161.023 1.00 105.22 ? 681  GLN A CG  1 
ATOM   846  C CD  . GLN A 1 670  ? 190.696 215.046 160.555 1.00 105.22 ? 681  GLN A CD  1 
ATOM   847  O OE1 . GLN A 1 670  ? 189.524 214.670 160.581 1.00 105.22 ? 681  GLN A OE1 1 
ATOM   848  N NE2 . GLN A 1 670  ? 191.052 216.250 160.122 1.00 105.22 ? 681  GLN A NE2 1 
ATOM   849  N N   . ALA A 1 671  ? 191.712 211.878 165.105 1.00 106.10 ? 682  ALA A N   1 
ATOM   850  C CA  . ALA A 1 671  ? 191.426 211.873 166.535 1.00 106.10 ? 682  ALA A CA  1 
ATOM   851  C C   . ALA A 1 671  ? 192.707 211.826 167.359 1.00 106.10 ? 682  ALA A C   1 
ATOM   852  O O   . ALA A 1 671  ? 192.834 212.539 168.361 1.00 106.10 ? 682  ALA A O   1 
ATOM   853  C CB  . ALA A 1 671  ? 190.519 210.693 166.886 1.00 106.10 ? 682  ALA A CB  1 
ATOM   854  N N   . GLN A 1 672  ? 193.669 210.997 166.955 1.00 107.90 ? 683  GLN A N   1 
ATOM   855  C CA  . GLN A 1 672  ? 194.939 210.946 167.672 1.00 107.90 ? 683  GLN A CA  1 
ATOM   856  C C   . GLN A 1 672  ? 195.915 212.033 167.237 1.00 107.90 ? 683  GLN A C   1 
ATOM   857  O O   . GLN A 1 672  ? 197.019 212.104 167.789 1.00 107.90 ? 683  GLN A O   1 
ATOM   858  C CB  . GLN A 1 672  ? 195.602 209.573 167.519 1.00 107.90 ? 683  GLN A CB  1 
ATOM   859  C CG  . GLN A 1 672  ? 194.660 208.444 167.158 1.00 107.90 ? 683  GLN A CG  1 
ATOM   860  C CD  . GLN A 1 672  ? 195.263 207.078 167.416 1.00 107.90 ? 683  GLN A CD  1 
ATOM   861  O OE1 . GLN A 1 672  ? 196.484 206.920 167.437 1.00 107.90 ? 683  GLN A OE1 1 
ATOM   862  N NE2 . GLN A 1 672  ? 194.409 206.081 167.613 1.00 107.90 ? 683  GLN A NE2 1 
ATOM   863  N N   . LEU A 1 673  ? 195.546 212.874 166.272 1.00 113.34 ? 684  LEU A N   1 
ATOM   864  C CA  . LEU A 1 673  ? 196.390 213.973 165.824 1.00 113.34 ? 684  LEU A CA  1 
ATOM   865  C C   . LEU A 1 673  ? 195.876 215.330 166.293 1.00 113.34 ? 684  LEU A C   1 
ATOM   866  O O   . LEU A 1 673  ? 196.260 216.361 165.730 1.00 113.34 ? 684  LEU A O   1 
ATOM   867  C CB  . LEU A 1 673  ? 196.518 213.957 164.301 1.00 113.34 ? 684  LEU A CB  1 
ATOM   868  C CG  . LEU A 1 673  ? 197.798 213.356 163.722 1.00 113.34 ? 684  LEU A CG  1 
ATOM   869  C CD1 . LEU A 1 673  ? 197.715 213.302 162.206 1.00 113.34 ? 684  LEU A CD1 1 
ATOM   870  C CD2 . LEU A 1 673  ? 199.013 214.150 164.168 1.00 113.34 ? 684  LEU A CD2 1 
ATOM   871  N N   . GLY A 1 674  ? 195.022 215.352 167.311 1.00 111.37 ? 685  GLY A N   1 
ATOM   872  C CA  . GLY A 1 674  ? 194.484 216.602 167.820 1.00 111.37 ? 685  GLY A CA  1 
ATOM   873  C C   . GLY A 1 674  ? 193.568 217.332 166.861 1.00 111.37 ? 685  GLY A C   1 
ATOM   874  O O   . GLY A 1 674  ? 193.650 218.561 166.746 1.00 111.37 ? 685  GLY A O   1 
ATOM   875  N N   . ASP A 1 675  ? 192.695 216.605 166.169 1.00 111.05 ? 686  ASP A N   1 
ATOM   876  C CA  . ASP A 1 675  ? 191.726 217.179 165.239 1.00 111.05 ? 686  ASP A CA  1 
ATOM   877  C C   . ASP A 1 675  ? 190.322 216.700 165.581 1.00 111.05 ? 686  ASP A C   1 
ATOM   878  O O   . ASP A 1 675  ? 189.569 216.229 164.727 1.00 111.05 ? 686  ASP A O   1 
ATOM   879  C CB  . ASP A 1 675  ? 192.076 216.841 163.793 1.00 111.05 ? 686  ASP A CB  1 
ATOM   880  C CG  . ASP A 1 675  ? 193.540 217.069 163.481 1.00 111.05 ? 686  ASP A CG  1 
ATOM   881  O OD1 . ASP A 1 675  ? 193.912 218.221 163.173 1.00 111.05 ? 686  ASP A OD1 1 
ATOM   882  O OD2 . ASP A 1 675  ? 194.319 216.096 163.538 1.00 111.05 ? 686  ASP A OD2 1 
ATOM   883  N N   . THR A 1 676  ? 189.959 216.810 166.863 1.00 105.91 ? 687  THR A N   1 
ATOM   884  C CA  . THR A 1 676  ? 188.631 216.390 167.298 1.00 105.91 ? 687  THR A CA  1 
ATOM   885  C C   . THR A 1 676  ? 187.532 217.183 166.603 1.00 105.91 ? 687  THR A C   1 
ATOM   886  O O   . THR A 1 676  ? 186.451 216.644 166.340 1.00 105.91 ? 687  THR A O   1 
ATOM   887  C CB  . THR A 1 676  ? 188.502 216.531 168.815 1.00 105.91 ? 687  THR A CB  1 
ATOM   888  O OG1 . THR A 1 676  ? 188.398 217.919 169.159 1.00 105.91 ? 687  THR A OG1 1 
ATOM   889  C CG2 . THR A 1 676  ? 189.715 215.932 169.510 1.00 105.91 ? 687  THR A CG2 1 
ATOM   890  N N   . ALA A 1 677  ? 187.791 218.452 166.282 1.00 103.47 ? 688  ALA A N   1 
ATOM   891  C CA  . ALA A 1 677  ? 186.812 219.308 165.624 1.00 103.47 ? 688  ALA A CA  1 
ATOM   892  C C   . ALA A 1 677  ? 186.480 218.852 164.208 1.00 103.47 ? 688  ALA A C   1 
ATOM   893  O O   . ALA A 1 677  ? 185.485 219.314 163.638 1.00 103.47 ? 688  ALA A O   1 
ATOM   894  C CB  . ALA A 1 677  ? 187.309 220.756 165.603 1.00 103.47 ? 688  ALA A CB  1 
ATOM   895  N N   . ALA A 1 678  ? 187.282 217.957 163.632 1.00 101.00 ? 689  ALA A N   1 
ATOM   896  C CA  . ALA A 1 678  ? 186.997 217.411 162.312 1.00 101.00 ? 689  ALA A CA  1 
ATOM   897  C C   . ALA A 1 678  ? 186.650 215.933 162.426 1.00 101.00 ? 689  ALA A C   1 
ATOM   898  O O   . ALA A 1 678  ? 185.857 215.407 161.636 1.00 101.00 ? 689  ALA A O   1 
ATOM   899  C CB  . ALA A 1 678  ? 188.187 217.616 161.374 1.00 101.00 ? 689  ALA A CB  1 
ATOM   900  N N   . ALA A 1 679  ? 187.238 215.256 163.416 1.00 99.07  ? 690  ALA A N   1 
ATOM   901  C CA  . ALA A 1 679  ? 186.906 213.856 163.653 1.00 99.07  ? 690  ALA A CA  1 
ATOM   902  C C   . ALA A 1 679  ? 185.452 213.703 164.081 1.00 99.07  ? 690  ALA A C   1 
ATOM   903  O O   . ALA A 1 679  ? 184.793 212.719 163.727 1.00 99.07  ? 690  ALA A O   1 
ATOM   904  C CB  . ALA A 1 679  ? 187.844 213.262 164.703 1.00 99.07  ? 690  ALA A CB  1 
ATOM   905  N N   . GLN A 1 680  ? 184.936 214.668 164.848 1.00 99.82  ? 691  GLN A N   1 
ATOM   906  C CA  . GLN A 1 680  ? 183.532 214.629 165.241 1.00 99.82  ? 691  GLN A CA  1 
ATOM   907  C C   . GLN A 1 680  ? 182.622 214.692 164.021 1.00 99.82  ? 691  GLN A C   1 
ATOM   908  O O   . GLN A 1 680  ? 181.658 213.927 163.914 1.00 99.82  ? 691  GLN A O   1 
ATOM   909  C CB  . GLN A 1 680  ? 183.223 215.775 166.205 1.00 99.82  ? 691  GLN A CB  1 
ATOM   910  C CG  . GLN A 1 680  ? 183.663 215.518 167.637 1.00 99.82  ? 691  GLN A CG  1 
ATOM   911  C CD  . GLN A 1 680  ? 183.183 216.591 168.593 1.00 99.82  ? 691  GLN A CD  1 
ATOM   912  O OE1 . GLN A 1 680  ? 182.964 217.736 168.199 1.00 99.82  ? 691  GLN A OE1 1 
ATOM   913  N NE2 . GLN A 1 680  ? 183.017 216.225 169.859 1.00 99.82  ? 691  GLN A NE2 1 
ATOM   914  N N   . ARG A 1 681  ? 182.921 215.594 163.082 1.00 97.29  ? 692  ARG A N   1 
ATOM   915  C CA  . ARG A 1 681  ? 182.131 215.676 161.856 1.00 97.29  ? 692  ARG A CA  1 
ATOM   916  C C   . ARG A 1 681  ? 182.268 214.405 161.028 1.00 97.29  ? 692  ARG A C   1 
ATOM   917  O O   . ARG A 1 681  ? 181.282 213.906 160.467 1.00 97.29  ? 692  ARG A O   1 
ATOM   918  C CB  . ARG A 1 681  ? 182.558 216.894 161.038 1.00 97.29  ? 692  ARG A CB  1 
ATOM   919  C CG  . ARG A 1 681  ? 181.733 218.143 161.297 1.00 97.29  ? 692  ARG A CG  1 
ATOM   920  C CD  . ARG A 1 681  ? 182.034 219.228 160.273 1.00 97.29  ? 692  ARG A CD  1 
ATOM   921  N NE  . ARG A 1 681  ? 183.434 219.231 159.865 1.00 97.29  ? 692  ARG A NE  1 
ATOM   922  C CZ  . ARG A 1 681  ? 184.424 219.749 160.580 1.00 97.29  ? 692  ARG A CZ  1 
ATOM   923  N NH1 . ARG A 1 681  ? 184.205 220.321 161.752 1.00 97.29  ? 692  ARG A NH1 1 
ATOM   924  N NH2 . ARG A 1 681  ? 185.665 219.693 160.105 1.00 97.29  ? 692  ARG A NH2 1 
ATOM   925  N N   . THR A 1 682  ? 183.486 213.865 160.942 1.00 93.31  ? 693  THR A N   1 
ATOM   926  C CA  . THR A 1 682  ? 183.702 212.648 160.168 1.00 93.31  ? 693  THR A CA  1 
ATOM   927  C C   . THR A 1 682  ? 182.878 211.494 160.724 1.00 93.31  ? 693  THR A C   1 
ATOM   928  O O   . THR A 1 682  ? 182.224 210.765 159.973 1.00 93.31  ? 693  THR A O   1 
ATOM   929  C CB  . THR A 1 682  ? 185.188 212.289 160.151 1.00 93.31  ? 693  THR A CB  1 
ATOM   930  O OG1 . THR A 1 682  ? 185.970 213.488 160.074 1.00 93.31  ? 693  THR A OG1 1 
ATOM   931  C CG2 . THR A 1 682  ? 185.506 211.407 158.953 1.00 93.31  ? 693  THR A CG2 1 
ATOM   932  N N   . PHE A 1 683  ? 182.869 211.330 162.048 1.00 87.94  ? 694  PHE A N   1 
ATOM   933  C CA  . PHE A 1 683  ? 182.099 210.234 162.627 1.00 87.94  ? 694  PHE A CA  1 
ATOM   934  C C   . PHE A 1 683  ? 180.600 210.514 162.591 1.00 87.94  ? 694  PHE A C   1 
ATOM   935  O O   . PHE A 1 683  ? 179.802 209.577 162.476 1.00 87.94  ? 694  PHE A O   1 
ATOM   936  C CB  . PHE A 1 683  ? 182.559 209.948 164.055 1.00 87.94  ? 694  PHE A CB  1 
ATOM   937  C CG  . PHE A 1 683  ? 183.563 208.836 164.149 1.00 87.94  ? 694  PHE A CG  1 
ATOM   938  C CD1 . PHE A 1 683  ? 184.920 209.103 164.101 1.00 87.94  ? 694  PHE A CD1 1 
ATOM   939  C CD2 . PHE A 1 683  ? 183.149 207.519 164.242 1.00 87.94  ? 694  PHE A CD2 1 
ATOM   940  C CE1 . PHE A 1 683  ? 185.845 208.079 164.179 1.00 87.94  ? 694  PHE A CE1 1 
ATOM   941  C CE2 . PHE A 1 683  ? 184.071 206.491 164.311 1.00 87.94  ? 694  PHE A CE2 1 
ATOM   942  C CZ  . PHE A 1 683  ? 185.419 206.772 164.282 1.00 87.94  ? 694  PHE A CZ  1 
ATOM   943  N N   . ASN A 1 684  ? 180.197 211.785 162.681 1.00 91.95  ? 695  ASN A N   1 
ATOM   944  C CA  . ASN A 1 684  ? 178.785 212.123 162.545 1.00 91.95  ? 695  ASN A CA  1 
ATOM   945  C C   . ASN A 1 684  ? 178.280 211.842 161.138 1.00 91.95  ? 695  ASN A C   1 
ATOM   946  O O   . ASN A 1 684  ? 177.081 211.617 160.944 1.00 91.95  ? 695  ASN A O   1 
ATOM   947  C CB  . ASN A 1 684  ? 178.558 213.590 162.909 1.00 91.95  ? 695  ASN A CB  1 
ATOM   948  C CG  . ASN A 1 684  ? 178.451 213.809 164.404 1.00 91.95  ? 695  ASN A CG  1 
ATOM   949  O OD1 . ASN A 1 684  ? 177.809 213.034 165.113 1.00 91.95  ? 695  ASN A OD1 1 
ATOM   950  N ND2 . ASN A 1 684  ? 179.084 214.868 164.894 1.00 91.95  ? 695  ASN A ND2 1 
ATOM   951  N N   . LYS A 1 685  ? 179.169 211.883 160.145 1.00 86.35  ? 696  LYS A N   1 
ATOM   952  C CA  . LYS A 1 685  ? 178.793 211.444 158.805 1.00 86.35  ? 696  LYS A CA  1 
ATOM   953  C C   . LYS A 1 685  ? 178.891 209.930 158.653 1.00 86.35  ? 696  LYS A C   1 
ATOM   954  O O   . LYS A 1 685  ? 178.125 209.336 157.886 1.00 86.35  ? 696  LYS A O   1 
ATOM   955  C CB  . LYS A 1 685  ? 179.668 212.136 157.759 1.00 86.35  ? 696  LYS A CB  1 
ATOM   956  C CG  . LYS A 1 685  ? 179.092 212.111 156.352 1.00 86.35  ? 696  LYS A CG  1 
ATOM   957  C CD  . LYS A 1 685  ? 180.193 212.105 155.304 1.00 86.35  ? 696  LYS A CD  1 
ATOM   958  C CE  . LYS A 1 685  ? 181.173 210.969 155.544 1.00 86.35  ? 696  LYS A CE  1 
ATOM   959  N NZ  . LYS A 1 685  ? 182.195 210.877 154.465 1.00 86.35  ? 696  LYS A NZ  1 
ATOM   960  N N   . LEU A 1 686  ? 179.821 209.306 159.382 1.00 86.89  ? 697  LEU A N   1 
ATOM   961  C CA  . LEU A 1 686  ? 180.079 207.849 159.219 1.00 86.89  ? 697  LEU A CA  1 
ATOM   962  C C   . LEU A 1 686  ? 179.019 206.978 159.905 1.00 86.89  ? 697  LEU A C   1 
ATOM   963  O O   . LEU A 1 686  ? 178.697 205.906 159.349 1.00 86.89  ? 697  LEU A O   1 
ATOM   964  C CB  . LEU A 1 686  ? 181.445 207.570 159.842 1.00 86.89  ? 697  LEU A CB  1 
ATOM   965  C CG  . LEU A 1 686  ? 182.636 207.409 158.894 1.00 86.89  ? 697  LEU A CG  1 
ATOM   966  C CD1 . LEU A 1 686  ? 182.548 206.133 158.085 1.00 86.89  ? 697  LEU A CD1 1 
ATOM   967  C CD2 . LEU A 1 686  ? 182.784 208.610 157.992 1.00 86.89  ? 697  LEU A CD2 1 
ATOM   968  N N   . ILE A 1 687  ? 178.501 207.398 161.060 1.00 81.93  ? 698  ILE A N   1 
ATOM   969  C CA  . ILE A 1 687  ? 177.612 206.521 161.828 1.00 81.93  ? 698  ILE A CA  1 
ATOM   970  C C   . ILE A 1 687  ? 176.247 206.331 161.172 1.00 81.93  ? 698  ILE A C   1 
ATOM   971  O O   . ILE A 1 687  ? 175.798 205.178 161.063 1.00 81.93  ? 698  ILE A O   1 
ATOM   972  C CB  . ILE A 1 687  ? 177.506 207.022 163.282 1.00 81.93  ? 698  ILE A CB  1 
ATOM   973  C CG1 . ILE A 1 687  ? 178.865 206.927 163.976 1.00 81.93  ? 698  ILE A CG1 1 
ATOM   974  C CG2 . ILE A 1 687  ? 176.469 206.223 164.047 1.00 81.93  ? 698  ILE A CG2 1 
ATOM   975  C CD1 . ILE A 1 687  ? 178.871 207.482 165.383 1.00 81.93  ? 698  ILE A CD1 1 
ATOM   976  N N   . PRO A 1 688  ? 175.529 207.382 160.746 1.00 82.46  ? 699  PRO A N   1 
ATOM   977  C CA  . PRO A 1 688  ? 174.204 207.145 160.143 1.00 82.46  ? 699  PRO A CA  1 
ATOM   978  C C   . PRO A 1 688  ? 174.242 206.266 158.906 1.00 82.46  ? 699  PRO A C   1 
ATOM   979  O O   . PRO A 1 688  ? 173.325 205.461 158.696 1.00 82.46  ? 699  PRO A O   1 
ATOM   980  C CB  . PRO A 1 688  ? 173.711 208.562 159.819 1.00 82.46  ? 699  PRO A CB  1 
ATOM   981  C CG  . PRO A 1 688  ? 174.434 209.433 160.776 1.00 82.46  ? 699  PRO A CG  1 
ATOM   982  C CD  . PRO A 1 688  ? 175.796 208.824 160.893 1.00 82.46  ? 699  PRO A CD  1 
ATOM   983  N N   . GLN A 1 689  ? 175.277 206.397 158.074 1.00 82.70  ? 700  GLN A N   1 
ATOM   984  C CA  . GLN A 1 689  ? 175.378 205.549 156.891 1.00 82.70  ? 700  GLN A CA  1 
ATOM   985  C C   . GLN A 1 689  ? 175.688 204.108 157.274 1.00 82.70  ? 700  GLN A C   1 
ATOM   986  O O   . GLN A 1 689  ? 175.204 203.170 156.628 1.00 82.70  ? 700  GLN A O   1 
ATOM   987  C CB  . GLN A 1 689  ? 176.443 206.097 155.942 1.00 82.70  ? 700  GLN A CB  1 
ATOM   988  C CG  . GLN A 1 689  ? 176.320 207.586 155.670 1.00 82.70  ? 700  GLN A CG  1 
ATOM   989  C CD  . GLN A 1 689  ? 177.558 208.163 155.015 1.00 82.70  ? 700  GLN A CD  1 
ATOM   990  O OE1 . GLN A 1 689  ? 178.498 207.438 154.690 1.00 82.70  ? 700  GLN A OE1 1 
ATOM   991  N NE2 . GLN A 1 689  ? 177.565 209.476 154.816 1.00 82.70  ? 700  GLN A NE2 1 
ATOM   992  N N   . ALA A 1 690  ? 176.493 203.911 158.320 1.00 80.70  ? 701  ALA A N   1 
ATOM   993  C CA  . ALA A 1 690  ? 176.798 202.561 158.776 1.00 80.70  ? 701  ALA A CA  1 
ATOM   994  C C   . ALA A 1 690  ? 175.587 201.894 159.416 1.00 80.70  ? 701  ALA A C   1 
ATOM   995  O O   . ALA A 1 690  ? 175.452 200.667 159.350 1.00 80.70  ? 701  ALA A O   1 
ATOM   996  C CB  . ALA A 1 690  ? 177.967 202.590 159.759 1.00 80.70  ? 701  ALA A CB  1 
ATOM   997  N N   . LYS A 1 691  ? 174.707 202.679 160.042 1.00 79.96  ? 702  LYS A N   1 
ATOM   998  C CA  . LYS A 1 691  ? 173.529 202.105 160.687 1.00 79.96  ? 702  LYS A CA  1 
ATOM   999  C C   . LYS A 1 691  ? 172.601 201.447 159.673 1.00 79.96  ? 702  LYS A C   1 
ATOM   1000 O O   . LYS A 1 691  ? 172.055 200.368 159.932 1.00 79.96  ? 702  LYS A O   1 
ATOM   1001 C CB  . LYS A 1 691  ? 172.781 203.181 161.473 1.00 79.96  ? 702  LYS A CB  1 
ATOM   1002 C CG  . LYS A 1 691  ? 173.448 203.588 162.776 1.00 79.96  ? 702  LYS A CG  1 
ATOM   1003 C CD  . LYS A 1 691  ? 172.602 204.607 163.525 1.00 79.96  ? 702  LYS A CD  1 
ATOM   1004 C CE  . LYS A 1 691  ? 173.195 204.931 164.886 1.00 79.96  ? 702  LYS A CE  1 
ATOM   1005 N NZ  . LYS A 1 691  ? 172.406 205.970 165.604 1.00 79.96  ? 702  LYS A NZ  1 
ATOM   1006 N N   . SER A 1 692  ? 172.408 202.082 158.514 1.00 78.57  ? 703  SER A N   1 
ATOM   1007 C CA  . SER A 1 692  ? 171.477 201.550 157.523 1.00 78.57  ? 703  SER A CA  1 
ATOM   1008 C C   . SER A 1 692  ? 171.985 200.257 156.898 1.00 78.57  ? 703  SER A C   1 
ATOM   1009 O O   . SER A 1 692  ? 171.182 199.437 156.439 1.00 78.57  ? 703  SER A O   1 
ATOM   1010 C CB  . SER A 1 692  ? 171.215 202.593 156.437 1.00 78.57  ? 703  SER A CB  1 
ATOM   1011 O OG  . SER A 1 692  ? 172.387 202.849 155.683 1.00 78.57  ? 703  SER A OG  1 
ATOM   1012 N N   . GLN A 1 693  ? 173.300 200.059 156.866 1.00 81.66  ? 704  GLN A N   1 
ATOM   1013 C CA  . GLN A 1 693  ? 173.859 198.868 156.251 1.00 81.66  ? 704  GLN A CA  1 
ATOM   1014 C C   . GLN A 1 693  ? 173.498 197.621 157.060 1.00 81.66  ? 704  GLN A C   1 
ATOM   1015 O O   . GLN A 1 693  ? 173.317 197.692 158.279 1.00 81.66  ? 704  GLN A O   1 
ATOM   1016 C CB  . GLN A 1 693  ? 175.376 198.994 156.130 1.00 81.66  ? 704  GLN A CB  1 
ATOM   1017 C CG  . GLN A 1 693  ? 175.824 200.011 155.096 1.00 81.66  ? 704  GLN A CG  1 
ATOM   1018 C CD  . GLN A 1 693  ? 177.293 199.882 154.748 1.00 81.66  ? 704  GLN A CD  1 
ATOM   1019 O OE1 . GLN A 1 693  ? 178.029 199.127 155.382 1.00 81.66  ? 704  GLN A OE1 1 
ATOM   1020 N NE2 . GLN A 1 693  ? 177.724 200.612 153.727 1.00 81.66  ? 704  GLN A NE2 1 
ATOM   1021 N N   . PRO A 1 694  ? 173.384 196.468 156.405 1.00 83.16  ? 705  PRO A N   1 
ATOM   1022 C CA  . PRO A 1 694  ? 173.058 195.231 157.125 1.00 83.16  ? 705  PRO A CA  1 
ATOM   1023 C C   . PRO A 1 694  ? 174.218 194.797 158.003 1.00 83.16  ? 705  PRO A C   1 
ATOM   1024 O O   . PRO A 1 694  ? 175.348 195.277 157.828 1.00 83.16  ? 705  PRO A O   1 
ATOM   1025 C CB  . PRO A 1 694  ? 172.789 194.212 156.003 1.00 83.16  ? 705  PRO A CB  1 
ATOM   1026 C CG  . PRO A 1 694  ? 173.038 194.910 154.711 1.00 83.16  ? 705  PRO A CG  1 
ATOM   1027 C CD  . PRO A 1 694  ? 173.648 196.240 154.974 1.00 83.16  ? 705  PRO A CD  1 
ATOM   1028 N N   . PRO A 1 695  ? 173.974 193.912 158.972 1.00 81.90  ? 706  PRO A N   1 
ATOM   1029 C CA  . PRO A 1 695  ? 175.050 193.503 159.884 1.00 81.90  ? 706  PRO A CA  1 
ATOM   1030 C C   . PRO A 1 695  ? 176.243 192.923 159.139 1.00 81.90  ? 706  PRO A C   1 
ATOM   1031 O O   . PRO A 1 695  ? 176.096 192.148 158.192 1.00 81.90  ? 706  PRO A O   1 
ATOM   1032 C CB  . PRO A 1 695  ? 174.378 192.448 160.770 1.00 81.90  ? 706  PRO A CB  1 
ATOM   1033 C CG  . PRO A 1 695  ? 172.935 192.808 160.746 1.00 81.90  ? 706  PRO A CG  1 
ATOM   1034 C CD  . PRO A 1 695  ? 172.668 193.360 159.375 1.00 81.90  ? 706  PRO A CD  1 
ATOM   1035 N N   . SER A 1 696  ? 177.434 193.310 159.584 1.00 83.20  ? 707  SER A N   1 
ATOM   1036 C CA  . SER A 1 696  ? 178.687 192.877 158.978 1.00 83.20  ? 707  SER A CA  1 
ATOM   1037 C C   . SER A 1 696  ? 179.806 193.126 159.984 1.00 83.20  ? 707  SER A C   1 
ATOM   1038 O O   . SER A 1 696  ? 179.554 193.422 161.157 1.00 83.20  ? 707  SER A O   1 
ATOM   1039 C CB  . SER A 1 696  ? 178.933 193.600 157.649 1.00 83.20  ? 707  SER A CB  1 
ATOM   1040 O OG  . SER A 1 696  ? 178.794 195.002 157.799 1.00 83.20  ? 707  SER A OG  1 
ATOM   1041 N N   . MET A 1 697  ? 181.047 193.003 159.514 1.00 86.58  ? 708  MET A N   1 
ATOM   1042 C CA  . MET A 1 697  ? 182.212 193.218 160.406 1.00 86.58  ? 708  MET A CA  1 
ATOM   1043 C C   . MET A 1 697  ? 182.583 194.703 160.385 1.00 86.58  ? 708  MET A C   1 
ATOM   1044 O O   . MET A 1 697  ? 182.645 195.313 161.472 1.00 86.58  ? 708  MET A O   1 
ATOM   1045 C CB  . MET A 1 697  ? 183.421 192.407 159.931 1.00 86.58  ? 708  MET A CB  1 
ATOM   1046 C CG  . MET A 1 697  ? 183.117 190.949 159.650 1.00 86.58  ? 708  MET A CG  1 
ATOM   1047 S SD  . MET A 1 697  ? 182.075 190.717 158.195 1.00 86.58  ? 708  MET A SD  1 
ATOM   1048 C CE  . MET A 1 697  ? 183.065 191.547 156.946 1.00 86.58  ? 708  MET A CE  1 
ATOM   1049 N N   . GLU A 1 698  ? 182.786 195.268 159.195 1.00 84.62  ? 709  GLU A N   1 
ATOM   1050 C CA  . GLU A 1 698  ? 183.247 196.650 159.107 1.00 84.62  ? 709  GLU A CA  1 
ATOM   1051 C C   . GLU A 1 698  ? 182.276 197.604 159.791 1.00 84.62  ? 709  GLU A C   1 
ATOM   1052 O O   . GLU A 1 698  ? 182.697 198.534 160.490 1.00 84.62  ? 709  GLU A O   1 
ATOM   1053 C CB  . GLU A 1 698  ? 183.446 197.043 157.642 1.00 84.62  ? 709  GLU A CB  1 
ATOM   1054 C CG  . GLU A 1 698  ? 183.235 198.523 157.356 1.00 84.62  ? 709  GLU A CG  1 
ATOM   1055 C CD  . GLU A 1 698  ? 184.347 199.398 157.909 1.00 84.62  ? 709  GLU A CD  1 
ATOM   1056 O OE1 . GLU A 1 698  ? 185.357 198.853 158.403 1.00 84.62  ? 709  GLU A OE1 1 
ATOM   1057 O OE2 . GLU A 1 698  ? 184.206 200.636 157.859 1.00 84.62  ? 709  GLU A OE2 1 
ATOM   1058 N N   . SER A 1 699  ? 180.972 197.395 159.595 1.00 79.54  ? 710  SER A N   1 
ATOM   1059 C CA  . SER A 1 699  ? 179.982 198.250 160.242 1.00 79.54  ? 710  SER A CA  1 
ATOM   1060 C C   . SER A 1 699  ? 180.052 198.123 161.758 1.00 79.54  ? 710  SER A C   1 
ATOM   1061 O O   . SER A 1 699  ? 179.967 199.125 162.477 1.00 79.54  ? 710  SER A O   1 
ATOM   1062 C CB  . SER A 1 699  ? 178.581 197.908 159.736 1.00 79.54  ? 710  SER A CB  1 
ATOM   1063 O OG  . SER A 1 699  ? 177.714 199.022 159.849 1.00 79.54  ? 710  SER A OG  1 
ATOM   1064 N N   . ALA A 1 700  ? 180.206 196.897 162.264 1.00 73.76  ? 711  ALA A N   1 
ATOM   1065 C CA  . ALA A 1 700  ? 180.332 196.707 163.705 1.00 73.76  ? 711  ALA A CA  1 
ATOM   1066 C C   . ALA A 1 700  ? 181.581 197.391 164.245 1.00 73.76  ? 711  ALA A C   1 
ATOM   1067 O O   . ALA A 1 700  ? 181.538 198.040 165.298 1.00 73.76  ? 711  ALA A O   1 
ATOM   1068 C CB  . ALA A 1 700  ? 180.354 195.217 164.038 1.00 73.76  ? 711  ALA A CB  1 
ATOM   1069 N N   . MET A 1 701  ? 182.695 197.246 163.521 1.00 76.00  ? 712  MET A N   1 
ATOM   1070 C CA  . MET A 1 701  ? 183.968 197.879 163.954 1.00 76.00  ? 712  MET A CA  1 
ATOM   1071 C C   . MET A 1 701  ? 183.784 199.402 164.005 1.00 76.00  ? 712  MET A C   1 
ATOM   1072 O O   . MET A 1 701  ? 184.180 200.012 165.022 1.00 76.00  ? 712  MET A O   1 
ATOM   1073 C CB  . MET A 1 701  ? 185.110 197.539 162.990 1.00 76.00  ? 712  MET A CB  1 
ATOM   1074 C CG  . MET A 1 701  ? 185.561 196.093 163.054 1.00 76.00  ? 712  MET A CG  1 
ATOM   1075 S SD  . MET A 1 701  ? 186.858 195.715 161.859 1.00 76.00  ? 712  MET A SD  1 
ATOM   1076 C CE  . MET A 1 701  ? 188.142 196.857 162.388 1.00 76.00  ? 712  MET A CE  1 
ATOM   1077 N N   . VAL A 1 702  ? 183.200 199.988 162.955 1.00 76.21  ? 713  VAL A N   1 
ATOM   1078 C CA  . VAL A 1 702  ? 183.059 201.440 162.909 1.00 76.21  ? 713  VAL A CA  1 
ATOM   1079 C C   . VAL A 1 702  ? 182.081 201.923 163.974 1.00 76.21  ? 713  VAL A C   1 
ATOM   1080 O O   . VAL A 1 702  ? 182.288 202.986 164.569 1.00 76.21  ? 713  VAL A O   1 
ATOM   1081 C CB  . VAL A 1 702  ? 182.666 201.911 161.493 1.00 76.21  ? 713  VAL A CB  1 
ATOM   1082 C CG1 . VAL A 1 702  ? 181.184 201.721 161.226 1.00 76.21  ? 713  VAL A CG1 1 
ATOM   1083 C CG2 . VAL A 1 702  ? 183.053 203.369 161.297 1.00 76.21  ? 713  VAL A CG2 1 
ATOM   1084 N N   . LEU A 1 703  ? 181.022 201.158 164.257 1.00 76.45  ? 714  LEU A N   1 
ATOM   1085 C CA  . LEU A 1 703  ? 180.097 201.545 165.318 1.00 76.45  ? 714  LEU A CA  1 
ATOM   1086 C C   . LEU A 1 703  ? 180.778 201.505 166.680 1.00 76.45  ? 714  LEU A C   1 
ATOM   1087 O O   . LEU A 1 703  ? 180.598 202.412 167.503 1.00 76.45  ? 714  LEU A O   1 
ATOM   1088 C CB  . LEU A 1 703  ? 178.867 200.637 165.301 1.00 76.45  ? 714  LEU A CB  1 
ATOM   1089 C CG  . LEU A 1 703  ? 177.799 200.967 164.256 1.00 76.45  ? 714  LEU A CG  1 
ATOM   1090 C CD1 . LEU A 1 703  ? 176.597 200.049 164.409 1.00 76.45  ? 714  LEU A CD1 1 
ATOM   1091 C CD2 . LEU A 1 703  ? 177.382 202.425 164.361 1.00 76.45  ? 714  LEU A CD2 1 
ATOM   1092 N N   . ARG A 1 704  ? 181.569 200.461 166.937 1.00 77.96  ? 715  ARG A N   1 
ATOM   1093 C CA  . ARG A 1 704  ? 182.284 200.369 168.206 1.00 77.96  ? 715  ARG A CA  1 
ATOM   1094 C C   . ARG A 1 704  ? 183.284 201.510 168.353 1.00 77.96  ? 715  ARG A C   1 
ATOM   1095 O O   . ARG A 1 704  ? 183.397 202.122 169.424 1.00 77.96  ? 715  ARG A O   1 
ATOM   1096 C CB  . ARG A 1 704  ? 182.982 199.014 168.312 1.00 77.96  ? 715  ARG A CB  1 
ATOM   1097 C CG  . ARG A 1 704  ? 184.023 198.927 169.414 1.00 77.96  ? 715  ARG A CG  1 
ATOM   1098 C CD  . ARG A 1 704  ? 185.003 197.796 169.149 1.00 77.96  ? 715  ARG A CD  1 
ATOM   1099 N NE  . ARG A 1 704  ? 186.058 197.738 170.153 1.00 77.96  ? 715  ARG A NE  1 
ATOM   1100 C CZ  . ARG A 1 704  ? 187.054 196.862 170.141 1.00 77.96  ? 715  ARG A CZ  1 
ATOM   1101 N NH1 . ARG A 1 704  ? 187.165 195.955 169.185 1.00 77.96  ? 715  ARG A NH1 1 
ATOM   1102 N NH2 . ARG A 1 704  ? 187.961 196.898 171.113 1.00 77.96  ? 715  ARG A NH2 1 
ATOM   1103 N N   . ASP A 1 705  ? 183.994 201.828 167.267 1.00 80.11  ? 716  ASP A N   1 
ATOM   1104 C CA  . ASP A 1 705  ? 185.008 202.918 167.325 1.00 80.11  ? 716  ASP A CA  1 
ATOM   1105 C C   . ASP A 1 705  ? 184.296 204.261 167.514 1.00 80.11  ? 716  ASP A C   1 
ATOM   1106 O O   . ASP A 1 705  ? 184.841 205.117 168.241 1.00 80.11  ? 716  ASP A O   1 
ATOM   1107 C CB  . ASP A 1 705  ? 185.942 202.879 166.129 1.00 80.11  ? 716  ASP A CB  1 
ATOM   1108 C CG  . ASP A 1 705  ? 186.852 201.661 166.072 1.00 80.11  ? 716  ASP A CG  1 
ATOM   1109 O OD1 . ASP A 1 705  ? 186.756 200.818 166.988 1.00 80.11  ? 716  ASP A OD1 1 
ATOM   1110 O OD2 . ASP A 1 705  ? 187.648 201.566 165.115 1.00 80.11  ? 716  ASP A OD2 1 
ATOM   1111 N N   . GLY A 1 706  ? 183.125 204.442 166.898 1.00 80.07  ? 717  GLY A N   1 
ATOM   1112 C CA  . GLY A 1 706  ? 182.369 205.664 167.113 1.00 80.07  ? 717  GLY A CA  1 
ATOM   1113 C C   . GLY A 1 706  ? 181.876 205.793 168.539 1.00 80.07  ? 717  GLY A C   1 
ATOM   1114 O O   . GLY A 1 706  ? 181.887 206.881 169.117 1.00 80.07  ? 717  GLY A O   1 
ATOM   1115 N N   . ALA A 1 707  ? 181.432 204.680 169.124 1.00 80.39  ? 718  ALA A N   1 
ATOM   1116 C CA  . ALA A 1 707  ? 181.015 204.699 170.522 1.00 80.39  ? 718  ALA A CA  1 
ATOM   1117 C C   . ALA A 1 707  ? 182.183 205.059 171.431 1.00 80.39  ? 718  ALA A C   1 
ATOM   1118 O O   . ALA A 1 707  ? 182.037 205.858 172.365 1.00 80.39  ? 718  ALA A O   1 
ATOM   1119 C CB  . ALA A 1 707  ? 180.420 203.347 170.910 1.00 80.39  ? 718  ALA A CB  1 
ATOM   1120 N N   . LYS A 1 708  ? 183.360 204.486 171.164 1.00 78.91  ? 719  LYS A N   1 
ATOM   1121 C CA  . LYS A 1 708  ? 184.543 204.839 171.944 1.00 78.91  ? 719  LYS A CA  1 
ATOM   1122 C C   . LYS A 1 708  ? 184.882 206.317 171.798 1.00 78.91  ? 719  LYS A C   1 
ATOM   1123 O O   . LYS A 1 708  ? 185.216 206.987 172.783 1.00 78.91  ? 719  LYS A O   1 
ATOM   1124 C CB  . LYS A 1 708  ? 185.737 203.979 171.527 1.00 78.91  ? 719  LYS A CB  1 
ATOM   1125 C CG  . LYS A 1 708  ? 185.534 202.485 171.706 1.00 78.91  ? 719  LYS A CG  1 
ATOM   1126 C CD  . LYS A 1 708  ? 186.720 201.682 171.184 1.00 78.91  ? 719  LYS A CD  1 
ATOM   1127 C CE  . LYS A 1 708  ? 187.901 201.713 172.148 1.00 78.91  ? 719  LYS A CE  1 
ATOM   1128 N NZ  . LYS A 1 708  ? 188.724 202.949 172.027 1.00 78.91  ? 719  LYS A NZ  1 
ATOM   1129 N N   . PHE A 1 709  ? 184.804 206.844 170.574 1.00 84.16  ? 720  PHE A N   1 
ATOM   1130 C CA  . PHE A 1 709  ? 185.124 208.250 170.348 1.00 84.16  ? 720  PHE A CA  1 
ATOM   1131 C C   . PHE A 1 709  ? 184.140 209.161 171.072 1.00 84.16  ? 720  PHE A C   1 
ATOM   1132 O O   . PHE A 1 709  ? 184.537 210.167 171.672 1.00 84.16  ? 720  PHE A O   1 
ATOM   1133 C CB  . PHE A 1 709  ? 185.137 208.551 168.849 1.00 84.16  ? 720  PHE A CB  1 
ATOM   1134 C CG  . PHE A 1 709  ? 185.579 209.948 168.517 1.00 84.16  ? 720  PHE A CG  1 
ATOM   1135 C CD1 . PHE A 1 709  ? 186.614 210.545 169.217 1.00 84.16  ? 720  PHE A CD1 1 
ATOM   1136 C CD2 . PHE A 1 709  ? 184.960 210.664 167.506 1.00 84.16  ? 720  PHE A CD2 1 
ATOM   1137 C CE1 . PHE A 1 709  ? 187.024 211.828 168.915 1.00 84.16  ? 720  PHE A CE1 1 
ATOM   1138 C CE2 . PHE A 1 709  ? 185.366 211.948 167.199 1.00 84.16  ? 720  PHE A CE2 1 
ATOM   1139 C CZ  . PHE A 1 709  ? 186.399 212.531 167.905 1.00 84.16  ? 720  PHE A CZ  1 
ATOM   1140 N N   . GLU A 1 710  ? 182.848 208.826 171.024 1.00 85.05  ? 721  GLU A N   1 
ATOM   1141 C CA  . GLU A 1 710  ? 181.852 209.613 171.747 1.00 85.05  ? 721  GLU A CA  1 
ATOM   1142 C C   . GLU A 1 710  ? 182.082 209.541 173.250 1.00 85.05  ? 721  GLU A C   1 
ATOM   1143 O O   . GLU A 1 710  ? 181.870 210.526 173.967 1.00 85.05  ? 721  GLU A O   1 
ATOM   1144 C CB  . GLU A 1 710  ? 180.439 209.139 171.395 1.00 85.05  ? 721  GLU A CB  1 
ATOM   1145 C CG  . GLU A 1 710  ? 180.046 209.258 169.917 1.00 85.05  ? 721  GLU A CG  1 
ATOM   1146 C CD  . GLU A 1 710  ? 179.863 210.692 169.426 1.00 85.05  ? 721  GLU A CD  1 
ATOM   1147 O OE1 . GLU A 1 710  ? 179.048 210.890 168.501 1.00 85.05  ? 721  GLU A OE1 1 
ATOM   1148 O OE2 . GLU A 1 710  ? 180.517 211.619 169.948 1.00 85.05  ? 721  GLU A OE2 1 
ATOM   1149 N N   . ALA A 1 711  ? 182.508 208.378 173.748 1.00 83.37  ? 722  ALA A N   1 
ATOM   1150 C CA  . ALA A 1 711  ? 182.858 208.265 175.160 1.00 83.37  ? 722  ALA A CA  1 
ATOM   1151 C C   . ALA A 1 711  ? 184.032 209.174 175.503 1.00 83.37  ? 722  ALA A C   1 
ATOM   1152 O O   . ALA A 1 711  ? 184.036 209.837 176.547 1.00 83.37  ? 722  ALA A O   1 
ATOM   1153 C CB  . ALA A 1 711  ? 183.178 206.811 175.507 1.00 83.37  ? 722  ALA A CB  1 
ATOM   1154 N N   . GLN A 1 712  ? 185.042 209.216 174.632 1.00 84.47  ? 723  GLN A N   1 
ATOM   1155 C CA  . GLN A 1 712  ? 186.171 210.113 174.858 1.00 84.47  ? 723  GLN A CA  1 
ATOM   1156 C C   . GLN A 1 712  ? 185.786 211.562 174.584 1.00 84.47  ? 723  GLN A C   1 
ATOM   1157 O O   . GLN A 1 712  ? 186.400 212.488 175.126 1.00 84.47  ? 723  GLN A O   1 
ATOM   1158 C CB  . GLN A 1 712  ? 187.361 209.702 173.990 1.00 84.47  ? 723  GLN A CB  1 
ATOM   1159 C CG  . GLN A 1 712  ? 188.014 208.391 174.402 1.00 84.47  ? 723  GLN A CG  1 
ATOM   1160 C CD  . GLN A 1 712  ? 188.534 207.598 173.218 1.00 84.47  ? 723  GLN A CD  1 
ATOM   1161 O OE1 . GLN A 1 712  ? 187.873 207.491 172.185 1.00 84.47  ? 723  GLN A OE1 1 
ATOM   1162 N NE2 . GLN A 1 712  ? 189.727 207.031 173.365 1.00 84.47  ? 723  GLN A NE2 1 
ATOM   1163 N N   . ALA A 1 713  ? 184.775 211.778 173.738 1.00 87.18  ? 724  ALA A N   1 
ATOM   1164 C CA  . ALA A 1 713  ? 184.355 213.140 173.419 1.00 87.18  ? 724  ALA A CA  1 
ATOM   1165 C C   . ALA A 1 713  ? 183.776 213.842 174.640 1.00 87.18  ? 724  ALA A C   1 
ATOM   1166 O O   . ALA A 1 713  ? 183.963 215.052 174.816 1.00 87.18  ? 724  ALA A O   1 
ATOM   1167 C CB  . ALA A 1 713  ? 183.339 213.123 172.277 1.00 87.18  ? 724  ALA A CB  1 
ATOM   1168 N N   . GLY A 1 714  ? 183.071 213.104 175.493 1.00 85.23  ? 725  GLY A N   1 
ATOM   1169 C CA  . GLY A 1 714  ? 182.501 213.684 176.692 1.00 85.23  ? 725  GLY A CA  1 
ATOM   1170 C C   . GLY A 1 714  ? 181.067 213.270 176.951 1.00 85.23  ? 725  GLY A C   1 
ATOM   1171 O O   . GLY A 1 714  ? 180.643 213.179 178.107 1.00 85.23  ? 725  GLY A O   1 
ATOM   1172 N N   . ASP A 1 715  ? 180.311 213.019 175.892 1.00 85.31  ? 726  ASP A N   1 
ATOM   1173 C CA  . ASP A 1 715  ? 178.916 212.623 176.044 1.00 85.31  ? 726  ASP A CA  1 
ATOM   1174 C C   . ASP A 1 715  ? 178.819 211.114 176.232 1.00 85.31  ? 726  ASP A C   1 
ATOM   1175 O O   . ASP A 1 715  ? 179.183 210.361 175.319 1.00 85.31  ? 726  ASP A O   1 
ATOM   1176 C CB  . ASP A 1 715  ? 178.106 213.061 174.830 1.00 85.31  ? 726  ASP A CB  1 
ATOM   1177 C CG  . ASP A 1 715  ? 177.909 214.562 174.774 1.00 85.31  ? 726  ASP A CG  1 
ATOM   1178 O OD1 . ASP A 1 715  ? 178.146 215.232 175.801 1.00 85.31  ? 726  ASP A OD1 1 
ATOM   1179 O OD2 . ASP A 1 715  ? 177.519 215.073 173.703 1.00 85.31  ? 726  ASP A OD2 1 
ATOM   1180 N N   . PRO A 1 716  ? 178.341 210.629 177.379 1.00 81.63  ? 727  PRO A N   1 
ATOM   1181 C CA  . PRO A 1 716  ? 178.251 209.178 177.583 1.00 81.63  ? 727  PRO A CA  1 
ATOM   1182 C C   . PRO A 1 716  ? 176.967 208.575 177.035 1.00 81.63  ? 727  PRO A C   1 
ATOM   1183 O O   . PRO A 1 716  ? 176.933 207.388 176.698 1.00 81.63  ? 727  PRO A O   1 
ATOM   1184 C CB  . PRO A 1 716  ? 178.327 209.043 179.107 1.00 81.63  ? 727  PRO A CB  1 
ATOM   1185 C CG  . PRO A 1 716  ? 177.714 210.310 179.619 1.00 81.63  ? 727  PRO A CG  1 
ATOM   1186 C CD  . PRO A 1 716  ? 177.942 211.386 178.578 1.00 81.63  ? 727  PRO A CD  1 
ATOM   1187 N N   . THR A 1 717  ? 175.904 209.377 176.949 1.00 80.26  ? 728  THR A N   1 
ATOM   1188 C CA  . THR A 1 717  ? 174.620 208.866 176.478 1.00 80.26  ? 728  THR A CA  1 
ATOM   1189 C C   . THR A 1 717  ? 174.694 208.442 175.015 1.00 80.26  ? 728  THR A C   1 
ATOM   1190 O O   . THR A 1 717  ? 174.192 207.376 174.635 1.00 80.26  ? 728  THR A O   1 
ATOM   1191 C CB  . THR A 1 717  ? 173.531 209.922 176.677 1.00 80.26  ? 728  THR A CB  1 
ATOM   1192 O OG1 . THR A 1 717  ? 173.567 210.396 178.029 1.00 80.26  ? 728  THR A OG1 1 
ATOM   1193 C CG2 . THR A 1 717  ? 172.159 209.333 176.389 1.00 80.26  ? 728  THR A CG2 1 
ATOM   1194 N N   . GLN A 1 718  ? 175.318 209.271 174.176 1.00 83.31  ? 729  GLN A N   1 
ATOM   1195 C CA  . GLN A 1 718  ? 175.462 208.924 172.767 1.00 83.31  ? 729  GLN A CA  1 
ATOM   1196 C C   . GLN A 1 718  ? 176.332 207.685 172.596 1.00 83.31  ? 729  GLN A C   1 
ATOM   1197 O O   . GLN A 1 718  ? 176.048 206.828 171.749 1.00 83.31  ? 729  GLN A O   1 
ATOM   1198 C CB  . GLN A 1 718  ? 176.045 210.106 171.990 1.00 83.31  ? 729  GLN A CB  1 
ATOM   1199 C CG  . GLN A 1 718  ? 175.057 211.235 171.695 1.00 83.31  ? 729  GLN A CG  1 
ATOM   1200 C CD  . GLN A 1 718  ? 173.902 210.828 170.787 1.00 83.31  ? 729  GLN A CD  1 
ATOM   1201 O OE1 . GLN A 1 718  ? 173.809 209.684 170.339 1.00 83.31  ? 729  GLN A OE1 1 
ATOM   1202 N NE2 . GLN A 1 718  ? 173.012 211.774 170.515 1.00 83.31  ? 729  GLN A NE2 1 
ATOM   1203 N N   . ALA A 1 719  ? 177.394 207.573 173.395 1.00 81.87  ? 730  ALA A N   1 
ATOM   1204 C CA  . ALA A 1 719  ? 178.241 206.387 173.349 1.00 81.87  ? 730  ALA A CA  1 
ATOM   1205 C C   . ALA A 1 719  ? 177.458 205.142 173.746 1.00 81.87  ? 730  ALA A C   1 
ATOM   1206 O O   . ALA A 1 719  ? 177.612 204.076 173.140 1.00 81.87  ? 730  ALA A O   1 
ATOM   1207 C CB  . ALA A 1 719  ? 179.456 206.575 174.259 1.00 81.87  ? 730  ALA A CB  1 
ATOM   1208 N N   . LEU A 1 720  ? 176.609 205.260 174.769 1.00 80.59  ? 731  LEU A N   1 
ATOM   1209 C CA  . LEU A 1 720  ? 175.794 204.127 175.195 1.00 80.59  ? 731  LEU A CA  1 
ATOM   1210 C C   . LEU A 1 720  ? 174.811 203.716 174.105 1.00 80.59  ? 731  LEU A C   1 
ATOM   1211 O O   . LEU A 1 720  ? 174.609 202.523 173.852 1.00 80.59  ? 731  LEU A O   1 
ATOM   1212 C CB  . LEU A 1 720  ? 175.056 204.469 176.489 1.00 80.59  ? 731  LEU A CB  1 
ATOM   1213 C CG  . LEU A 1 720  ? 175.867 204.354 177.780 1.00 80.59  ? 731  LEU A CG  1 
ATOM   1214 C CD1 . LEU A 1 720  ? 175.084 204.912 178.959 1.00 80.59  ? 731  LEU A CD1 1 
ATOM   1215 C CD2 . LEU A 1 720  ? 176.270 202.910 178.034 1.00 80.59  ? 731  LEU A CD2 1 
ATOM   1216 N N   . GLU A 1 721  ? 174.185 204.697 173.450 1.00 82.26  ? 732  GLU A N   1 
ATOM   1217 C CA  . GLU A 1 721  ? 173.263 204.385 172.360 1.00 82.26  ? 732  GLU A CA  1 
ATOM   1218 C C   . GLU A 1 721  ? 173.988 203.702 171.205 1.00 82.26  ? 732  GLU A C   1 
ATOM   1219 O O   . GLU A 1 721  ? 173.486 202.733 170.621 1.00 82.26  ? 732  GLU A O   1 
ATOM   1220 C CB  . GLU A 1 721  ? 172.563 205.658 171.880 1.00 82.26  ? 732  GLU A CB  1 
ATOM   1221 C CG  . GLU A 1 721  ? 171.732 206.357 172.944 1.00 82.26  ? 732  GLU A CG  1 
ATOM   1222 C CD  . GLU A 1 721  ? 170.423 205.647 173.226 1.00 82.26  ? 732  GLU A CD  1 
ATOM   1223 O OE1 . GLU A 1 721  ? 170.435 204.644 173.971 1.00 82.26  ? 732  GLU A OE1 1 
ATOM   1224 O OE2 . GLU A 1 721  ? 169.380 206.091 172.701 1.00 82.26  ? 732  GLU A OE2 1 
ATOM   1225 N N   . THR A 1 722  ? 175.181 204.196 170.866 1.00 77.21  ? 733  THR A N   1 
ATOM   1226 C CA  . THR A 1 722  ? 175.959 203.587 169.793 1.00 77.21  ? 733  THR A CA  1 
ATOM   1227 C C   . THR A 1 722  ? 176.362 202.161 170.154 1.00 77.21  ? 733  THR A C   1 
ATOM   1228 O O   . THR A 1 722  ? 176.333 201.263 169.306 1.00 77.21  ? 733  THR A O   1 
ATOM   1229 C CB  . THR A 1 722  ? 177.192 204.438 169.491 1.00 77.21  ? 733  THR A CB  1 
ATOM   1230 O OG1 . THR A 1 722  ? 176.802 205.809 169.340 1.00 77.21  ? 733  THR A OG1 1 
ATOM   1231 C CG2 . THR A 1 722  ? 177.858 203.968 168.209 1.00 77.21  ? 733  THR A CG2 1 
ATOM   1232 N N   . TYR A 1 723  ? 176.743 201.937 171.413 1.00 78.60  ? 734  TYR A N   1 
ATOM   1233 C CA  . TYR A 1 723  ? 177.090 200.595 171.868 1.00 78.60  ? 734  TYR A CA  1 
ATOM   1234 C C   . TYR A 1 723  ? 175.888 199.662 171.785 1.00 78.60  ? 734  TYR A C   1 
ATOM   1235 O O   . TYR A 1 723  ? 176.011 198.497 171.390 1.00 78.60  ? 734  TYR A O   1 
ATOM   1236 C CB  . TYR A 1 723  ? 177.629 200.656 173.298 1.00 78.60  ? 734  TYR A CB  1 
ATOM   1237 C CG  . TYR A 1 723  ? 179.122 200.854 173.381 1.00 78.60  ? 734  TYR A CG  1 
ATOM   1238 C CD1 . TYR A 1 723  ? 179.976 200.231 172.482 1.00 78.60  ? 734  TYR A CD1 1 
ATOM   1239 C CD2 . TYR A 1 723  ? 179.680 201.666 174.359 1.00 78.60  ? 734  TYR A CD2 1 
ATOM   1240 C CE1 . TYR A 1 723  ? 181.342 200.413 172.553 1.00 78.60  ? 734  TYR A CE1 1 
ATOM   1241 C CE2 . TYR A 1 723  ? 181.044 201.852 174.439 1.00 78.60  ? 734  TYR A CE2 1 
ATOM   1242 C CZ  . TYR A 1 723  ? 181.870 201.223 173.535 1.00 78.60  ? 734  TYR A CZ  1 
ATOM   1243 O OH  . TYR A 1 723  ? 183.230 201.408 173.615 1.00 78.60  ? 734  TYR A OH  1 
ATOM   1244 N N   . LYS A 1 724  ? 174.712 200.163 172.169 1.00 81.00  ? 735  LYS A N   1 
ATOM   1245 C CA  . LYS A 1 724  ? 173.495 199.364 172.067 1.00 81.00  ? 735  LYS A CA  1 
ATOM   1246 C C   . LYS A 1 724  ? 173.203 198.994 170.620 1.00 81.00  ? 735  LYS A C   1 
ATOM   1247 O O   . LYS A 1 724  ? 172.810 197.859 170.325 1.00 81.00  ? 735  LYS A O   1 
ATOM   1248 C CB  . LYS A 1 724  ? 172.313 200.127 172.669 1.00 81.00  ? 735  LYS A CB  1 
ATOM   1249 C CG  . LYS A 1 724  ? 172.291 200.156 174.187 1.00 81.00  ? 735  LYS A CG  1 
ATOM   1250 C CD  . LYS A 1 724  ? 171.082 200.923 174.700 1.00 81.00  ? 735  LYS A CD  1 
ATOM   1251 C CE  . LYS A 1 724  ? 171.038 200.937 176.219 1.00 81.00  ? 735  LYS A CE  1 
ATOM   1252 N NZ  . LYS A 1 724  ? 169.889 201.734 176.729 1.00 81.00  ? 735  LYS A NZ  1 
ATOM   1253 N N   . ASP A 1 725  ? 173.391 199.943 169.702 1.00 83.37  ? 736  ASP A N   1 
ATOM   1254 C CA  . ASP A 1 725  ? 173.145 199.668 168.290 1.00 83.37  ? 736  ASP A CA  1 
ATOM   1255 C C   . ASP A 1 725  ? 174.171 198.684 167.731 1.00 83.37  ? 736  ASP A C   1 
ATOM   1256 O O   . ASP A 1 725  ? 173.825 197.830 166.906 1.00 83.37  ? 736  ASP A O   1 
ATOM   1257 C CB  . ASP A 1 725  ? 173.157 200.987 167.508 1.00 83.37  ? 736  ASP A CB  1 
ATOM   1258 C CG  . ASP A 1 725  ? 172.732 200.834 166.049 1.00 83.37  ? 736  ASP A CG  1 
ATOM   1259 O OD1 . ASP A 1 725  ? 172.405 201.869 165.432 1.00 83.37  ? 736  ASP A OD1 1 
ATOM   1260 O OD2 . ASP A 1 725  ? 172.696 199.710 165.512 1.00 83.37  ? 736  ASP A OD2 1 
ATOM   1261 N N   . ALA A 1 726  ? 175.422 198.760 168.198 1.00 83.12  ? 737  ALA A N   1 
ATOM   1262 C CA  . ALA A 1 726  ? 176.510 198.015 167.569 1.00 83.12  ? 737  ALA A CA  1 
ATOM   1263 C C   . ALA A 1 726  ? 176.303 196.506 167.627 1.00 83.12  ? 737  ALA A C   1 
ATOM   1264 O O   . ALA A 1 726  ? 176.822 195.782 166.770 1.00 83.12  ? 737  ALA A O   1 
ATOM   1265 C CB  . ALA A 1 726  ? 177.841 198.387 168.222 1.00 83.12  ? 737  ALA A CB  1 
ATOM   1266 N N   . MET A 1 727  ? 175.529 196.059 168.616 1.00 83.99  ? 738  MET A N   1 
ATOM   1267 C CA  . MET A 1 727  ? 175.288 194.605 168.793 1.00 83.99  ? 738  MET A CA  1 
ATOM   1268 C C   . MET A 1 727  ? 174.533 194.055 167.572 1.00 83.99  ? 738  MET A C   1 
ATOM   1269 O O   . MET A 1 727  ? 174.781 192.887 167.200 1.00 83.99  ? 738  MET A O   1 
ATOM   1270 C CB  . MET A 1 727  ? 174.493 194.359 170.079 1.00 83.99  ? 738  MET A CB  1 
ATOM   1271 C CG  . MET A 1 727  ? 175.174 194.911 171.314 1.00 83.99  ? 738  MET A CG  1 
ATOM   1272 S SD  . MET A 1 727  ? 174.365 194.440 172.856 1.00 83.99  ? 738  MET A SD  1 
ATOM   1273 C CE  . MET A 1 727  ? 175.455 195.233 174.045 1.00 83.99  ? 738  MET A CE  1 
ATOM   1274 N N   . VAL A 1 728  ? 173.661 194.864 166.970 1.00 83.10  ? 739  VAL A N   1 
ATOM   1275 C CA  . VAL A 1 728  ? 172.891 194.432 165.807 1.00 83.10  ? 739  VAL A CA  1 
ATOM   1276 C C   . VAL A 1 728  ? 173.818 194.157 164.630 1.00 83.10  ? 739  VAL A C   1 
ATOM   1277 O O   . VAL A 1 728  ? 173.675 193.148 163.929 1.00 83.10  ? 739  VAL A O   1 
ATOM   1278 C CB  . VAL A 1 728  ? 171.820 195.479 165.454 1.00 83.10  ? 739  VAL A CB  1 
ATOM   1279 C CG1 . VAL A 1 728  ? 170.917 194.961 164.346 1.00 83.10  ? 739  VAL A CG1 1 
ATOM   1280 C CG2 . VAL A 1 728  ? 171.007 195.841 166.687 1.00 83.10  ? 739  VAL A CG2 1 
ATOM   1281 N N   . ALA A 1 729  ? 174.783 195.049 164.394 1.00 81.27  ? 740  ALA A N   1 
ATOM   1282 C CA  . ALA A 1 729  ? 175.708 194.862 163.281 1.00 81.27  ? 740  ALA A CA  1 
ATOM   1283 C C   . ALA A 1 729  ? 176.685 193.724 163.549 1.00 81.27  ? 740  ALA A C   1 
ATOM   1284 O O   . ALA A 1 729  ? 177.005 192.947 162.641 1.00 81.27  ? 740  ALA A O   1 
ATOM   1285 C CB  . ALA A 1 729  ? 176.462 196.162 163.003 1.00 81.27  ? 740  ALA A CB  1 
ATOM   1286 N N   . SER A 1 730  ? 177.175 193.612 164.785 1.00 79.22  ? 741  SER A N   1 
ATOM   1287 C CA  . SER A 1 730  ? 178.159 192.580 165.099 1.00 79.22  ? 741  SER A CA  1 
ATOM   1288 C C   . SER A 1 730  ? 177.547 191.187 165.038 1.00 79.22  ? 741  SER A C   1 
ATOM   1289 O O   . SER A 1 730  ? 178.155 190.260 164.489 1.00 79.22  ? 741  SER A O   1 
ATOM   1290 C CB  . SER A 1 730  ? 178.767 192.840 166.476 1.00 79.22  ? 741  SER A CB  1 
ATOM   1291 O OG  . SER A 1 730  ? 177.767 192.866 167.475 1.00 79.22  ? 741  SER A OG  1 
ATOM   1292 N N   . GLY A 1 731  ? 176.352 191.017 165.595 1.00 84.28  ? 742  GLY A N   1 
ATOM   1293 C CA  . GLY A 1 731  ? 175.697 189.725 165.587 1.00 84.28  ? 742  GLY A CA  1 
ATOM   1294 C C   . GLY A 1 731  ? 175.421 189.171 166.969 1.00 84.28  ? 742  GLY A C   1 
ATOM   1295 O O   . GLY A 1 731  ? 175.021 188.011 167.108 1.00 84.28  ? 742  GLY A O   1 
ATOM   1296 N N   . VAL A 1 732  ? 175.640 189.988 168.003 1.00 85.37  ? 743  VAL A N   1 
ATOM   1297 C CA  . VAL A 1 732  ? 175.327 189.559 169.364 1.00 85.37  ? 743  VAL A CA  1 
ATOM   1298 C C   . VAL A 1 732  ? 173.832 189.313 169.513 1.00 85.37  ? 743  VAL A C   1 
ATOM   1299 O O   . VAL A 1 732  ? 173.407 188.313 170.105 1.00 85.37  ? 743  VAL A O   1 
ATOM   1300 C CB  . VAL A 1 732  ? 175.834 190.595 170.384 1.00 85.37  ? 743  VAL A CB  1 
ATOM   1301 C CG1 . VAL A 1 732  ? 175.809 190.010 171.785 1.00 85.37  ? 743  VAL A CG1 1 
ATOM   1302 C CG2 . VAL A 1 732  ? 177.238 191.044 170.026 1.00 85.37  ? 743  VAL A CG2 1 
ATOM   1303 N N   . THR A 1 733  ? 173.012 190.216 168.982 1.00 88.77  ? 744  THR A N   1 
ATOM   1304 C CA  . THR A 1 733  ? 171.565 190.085 169.025 1.00 88.77  ? 744  THR A CA  1 
ATOM   1305 C C   . THR A 1 733  ? 170.983 190.469 167.672 1.00 88.77  ? 744  THR A C   1 
ATOM   1306 O O   . THR A 1 733  ? 171.555 191.266 166.924 1.00 88.77  ? 744  THR A O   1 
ATOM   1307 C CB  . THR A 1 733  ? 170.954 190.955 170.132 1.00 88.77  ? 744  THR A CB  1 
ATOM   1308 O OG1 . THR A 1 733  ? 169.527 190.973 169.996 1.00 88.77  ? 744  THR A OG1 1 
ATOM   1309 C CG2 . THR A 1 733  ? 171.484 192.377 170.045 1.00 88.77  ? 744  THR A CG2 1 
ATOM   1310 N N   . THR A 1 734  ? 169.825 189.887 167.362 1.00 89.23  ? 745  THR A N   1 
ATOM   1311 C CA  . THR A 1 734  ? 169.102 190.199 166.139 1.00 89.23  ? 745  THR A CA  1 
ATOM   1312 C C   . THR A 1 734  ? 168.287 191.480 166.250 1.00 89.23  ? 745  THR A C   1 
ATOM   1313 O O   . THR A 1 734  ? 168.213 192.239 165.276 1.00 89.23  ? 745  THR A O   1 
ATOM   1314 C CB  . THR A 1 734  ? 168.180 189.026 165.763 1.00 89.23  ? 745  THR A CB  1 
ATOM   1315 O OG1 . THR A 1 734  ? 168.970 187.941 165.261 1.00 89.23  ? 745  THR A OG1 1 
ATOM   1316 C CG2 . THR A 1 734  ? 167.167 189.434 164.701 1.00 89.23  ? 745  THR A CG2 1 
ATOM   1317 N N   . THR A 1 735  ? 167.718 191.762 167.418 1.00 89.60  ? 746  THR A N   1 
ATOM   1318 C CA  . THR A 1 735  ? 166.890 192.938 167.633 1.00 89.60  ? 746  THR A CA  1 
ATOM   1319 C C   . THR A 1 735  ? 167.611 193.892 168.573 1.00 89.60  ? 746  THR A C   1 
ATOM   1320 O O   . THR A 1 735  ? 168.271 193.461 169.523 1.00 89.60  ? 746  THR A O   1 
ATOM   1321 C CB  . THR A 1 735  ? 165.523 192.558 168.218 1.00 89.60  ? 746  THR A CB  1 
ATOM   1322 O OG1 . THR A 1 735  ? 165.002 191.422 167.517 1.00 89.60  ? 746  THR A OG1 1 
ATOM   1323 C CG2 . THR A 1 735  ? 164.545 193.715 168.088 1.00 89.60  ? 746  THR A CG2 1 
ATOM   1324 N N   . ARG A 1 736  ? 167.488 195.184 168.295 1.00 89.19  ? 747  ARG A N   1 
ATOM   1325 C CA  . ARG A 1 736  ? 168.141 196.190 169.118 1.00 89.19  ? 747  ARG A CA  1 
ATOM   1326 C C   . ARG A 1 736  ? 167.556 196.172 170.528 1.00 89.19  ? 747  ARG A C   1 
ATOM   1327 O O   . ARG A 1 736  ? 166.327 196.170 170.683 1.00 89.19  ? 747  ARG A O   1 
ATOM   1328 C CB  . ARG A 1 736  ? 167.975 197.575 168.495 1.00 89.19  ? 747  ARG A CB  1 
ATOM   1329 C CG  . ARG A 1 736  ? 168.591 198.699 169.307 1.00 89.19  ? 747  ARG A CG  1 
ATOM   1330 C CD  . ARG A 1 736  ? 168.375 200.042 168.633 1.00 89.19  ? 747  ARG A CD  1 
ATOM   1331 N NE  . ARG A 1 736  ? 169.308 201.050 169.123 1.00 89.19  ? 747  ARG A NE  1 
ATOM   1332 C CZ  . ARG A 1 736  ? 169.078 201.837 170.164 1.00 89.19  ? 747  ARG A CZ  1 
ATOM   1333 N NH1 . ARG A 1 736  ? 167.953 201.759 170.855 1.00 89.19  ? 747  ARG A NH1 1 
ATOM   1334 N NH2 . ARG A 1 736  ? 170.002 202.724 170.523 1.00 89.19  ? 747  ARG A NH2 1 
ATOM   1335 N N   . PRO A 1 737  ? 168.387 196.139 171.569 1.00 88.39  ? 748  PRO A N   1 
ATOM   1336 C CA  . PRO A 1 737  ? 167.856 196.178 172.937 1.00 88.39  ? 748  PRO A CA  1 
ATOM   1337 C C   . PRO A 1 737  ? 167.092 197.467 173.198 1.00 88.39  ? 748  PRO A C   1 
ATOM   1338 O O   . PRO A 1 737  ? 167.458 198.539 172.712 1.00 88.39  ? 748  PRO A O   1 
ATOM   1339 C CB  . PRO A 1 737  ? 169.113 196.082 173.809 1.00 88.39  ? 748  PRO A CB  1 
ATOM   1340 C CG  . PRO A 1 737  ? 170.155 195.484 172.919 1.00 88.39  ? 748  PRO A CG  1 
ATOM   1341 C CD  . PRO A 1 737  ? 169.852 195.998 171.547 1.00 88.39  ? 748  PRO A CD  1 
ATOM   1342 N N   . GLN A 1 738  ? 166.042 197.373 174.020 1.00 92.30  ? 749  GLN A N   1 
ATOM   1343 C CA  . GLN A 1 738  ? 165.207 198.566 174.317 1.00 92.30  ? 749  GLN A CA  1 
ATOM   1344 C C   . GLN A 1 738  ? 165.194 198.839 175.828 1.00 92.30  ? 749  GLN A C   1 
ATOM   1345 O O   . GLN A 1 738  ? 164.556 199.831 176.239 1.00 92.30  ? 749  GLN A O   1 
ATOM   1346 C CB  . GLN A 1 738  ? 163.783 198.344 173.808 1.00 92.30  ? 749  GLN A CB  1 
ATOM   1347 C CG  . GLN A 1 738  ? 163.000 197.282 174.573 1.00 92.30  ? 749  GLN A CG  1 
ATOM   1348 C CD  . GLN A 1 738  ? 163.343 195.863 174.174 1.00 92.30  ? 749  GLN A CD  1 
ATOM   1349 O OE1 . GLN A 1 738  ? 164.479 195.401 174.328 1.00 92.30  ? 749  GLN A OE1 1 
ATOM   1350 N NE2 . GLN A 1 738  ? 162.351 195.148 173.662 1.00 92.30  ? 749  GLN A NE2 1 
ATOM   1351 N N   . ASP A 1 739  ? 165.879 198.010 176.619 1.00 88.96  ? 750  ASP A N   1 
ATOM   1352 C CA  . ASP A 1 739  ? 165.852 198.165 178.065 1.00 88.96  ? 750  ASP A CA  1 
ATOM   1353 C C   . ASP A 1 739  ? 167.246 197.915 178.618 1.00 88.96  ? 750  ASP A C   1 
ATOM   1354 O O   . ASP A 1 739  ? 168.073 197.256 177.983 1.00 88.96  ? 750  ASP A O   1 
ATOM   1355 C CB  . ASP A 1 739  ? 164.842 197.213 178.717 1.00 88.96  ? 750  ASP A CB  1 
ATOM   1356 C CG  . ASP A 1 739  ? 165.177 195.756 178.475 1.00 88.96  ? 750  ASP A CG  1 
ATOM   1357 O OD1 . ASP A 1 739  ? 164.814 195.232 177.402 1.00 88.96  ? 750  ASP A OD1 1 
ATOM   1358 O OD2 . ASP A 1 739  ? 165.806 195.135 179.358 1.00 88.96  ? 750  ASP A OD2 1 
ATOM   1359 N N   . ASN A 1 740  ? 167.494 198.448 179.813 1.00 85.14  ? 751  ASN A N   1 
ATOM   1360 C CA  . ASN A 1 740  ? 168.839 198.308 180.429 1.00 85.14  ? 751  ASN A CA  1 
ATOM   1361 C C   . ASN A 1 740  ? 169.098 196.839 180.776 1.00 85.14  ? 751  ASN A C   1 
ATOM   1362 O O   . ASN A 1 740  ? 170.234 196.376 180.562 1.00 85.14  ? 751  ASN A O   1 
ATOM   1363 C CB  . ASN A 1 740  ? 168.970 199.232 181.633 1.00 85.14  ? 751  ASN A CB  1 
ATOM   1364 C CG  . ASN A 1 740  ? 168.797 200.682 181.252 1.00 85.14  ? 751  ASN A CG  1 
ATOM   1365 O OD1 . ASN A 1 740  ? 168.572 200.992 180.078 1.00 85.14  ? 751  ASN A OD1 1 
ATOM   1366 N ND2 . ASN A 1 740  ? 168.899 201.578 182.222 1.00 85.14  ? 751  ASN A ND2 1 
ATOM   1367 N N   . ASP A 1 741  ? 168.087 196.127 181.274 1.00 86.65  ? 752  ASP A N   1 
ATOM   1368 C CA  . ASP A 1 741  ? 168.301 194.750 181.709 1.00 86.65  ? 752  ASP A CA  1 
ATOM   1369 C C   . ASP A 1 741  ? 168.775 193.876 180.555 1.00 86.65  ? 752  ASP A C   1 
ATOM   1370 O O   . ASP A 1 741  ? 169.721 193.094 180.702 1.00 86.65  ? 752  ASP A O   1 
ATOM   1371 C CB  . ASP A 1 741  ? 167.017 194.189 182.321 1.00 86.65  ? 752  ASP A CB  1 
ATOM   1372 C CG  . ASP A 1 741  ? 166.867 194.548 183.786 1.00 86.65  ? 752  ASP A CG  1 
ATOM   1373 O OD1 . ASP A 1 741  ? 167.703 195.322 184.298 1.00 86.65  ? 752  ASP A OD1 1 
ATOM   1374 O OD2 . ASP A 1 741  ? 165.914 194.056 184.425 1.00 86.65  ? 752  ASP A OD2 1 
ATOM   1375 N N   . THR A 1 742  ? 168.137 194.008 179.389 1.00 82.37  ? 753  THR A N   1 
ATOM   1376 C CA  . THR A 1 742  ? 168.579 193.259 178.217 1.00 82.37  ? 753  THR A CA  1 
ATOM   1377 C C   . THR A 1 742  ? 169.979 193.683 177.793 1.00 82.37  ? 753  THR A C   1 
ATOM   1378 O O   . THR A 1 742  ? 170.781 192.850 177.354 1.00 82.37  ? 753  THR A O   1 
ATOM   1379 C CB  . THR A 1 742  ? 167.586 193.443 177.069 1.00 82.37  ? 753  THR A CB  1 
ATOM   1380 O OG1 . THR A 1 742  ? 166.279 193.044 177.498 1.00 82.37  ? 753  THR A OG1 1 
ATOM   1381 C CG2 . THR A 1 742  ? 167.992 192.602 175.867 1.00 82.37  ? 753  THR A CG2 1 
ATOM   1382 N N   . PHE A 1 743  ? 170.293 194.974 177.924 1.00 82.51  ? 754  PHE A N   1 
ATOM   1383 C CA  . PHE A 1 743  ? 171.627 195.461 177.589 1.00 82.51  ? 754  PHE A CA  1 
ATOM   1384 C C   . PHE A 1 743  ? 172.694 194.764 178.427 1.00 82.51  ? 754  PHE A C   1 
ATOM   1385 O O   . PHE A 1 743  ? 173.643 194.175 177.889 1.00 82.51  ? 754  PHE A O   1 
ATOM   1386 C CB  . PHE A 1 743  ? 171.674 196.977 177.792 1.00 82.51  ? 754  PHE A CB  1 
ATOM   1387 C CG  . PHE A 1 743  ? 173.033 197.584 177.600 1.00 82.51  ? 754  PHE A CG  1 
ATOM   1388 C CD1 . PHE A 1 743  ? 173.623 197.620 176.349 1.00 82.51  ? 754  PHE A CD1 1 
ATOM   1389 C CD2 . PHE A 1 743  ? 173.716 198.131 178.673 1.00 82.51  ? 754  PHE A CD2 1 
ATOM   1390 C CE1 . PHE A 1 743  ? 174.872 198.187 176.174 1.00 82.51  ? 754  PHE A CE1 1 
ATOM   1391 C CE2 . PHE A 1 743  ? 174.965 198.697 178.504 1.00 82.51  ? 754  PHE A CE2 1 
ATOM   1392 C CZ  . PHE A 1 743  ? 175.544 198.724 177.252 1.00 82.51  ? 754  PHE A CZ  1 
ATOM   1393 N N   . THR A 1 744  ? 172.506 194.787 179.752 1.00 82.04  ? 755  THR A N   1 
ATOM   1394 C CA  . THR A 1 744  ? 173.474 194.148 180.673 1.00 82.04  ? 755  THR A CA  1 
ATOM   1395 C C   . THR A 1 744  ? 173.519 192.654 180.420 1.00 82.04  ? 755  THR A C   1 
ATOM   1396 O O   . THR A 1 744  ? 174.619 192.072 180.501 1.00 82.04  ? 755  THR A O   1 
ATOM   1397 C CB  . THR A 1 744  ? 173.079 194.451 182.117 1.00 82.04  ? 755  THR A CB  1 
ATOM   1398 O OG1 . THR A 1 744  ? 171.780 193.892 182.274 1.00 82.04  ? 755  THR A OG1 1 
ATOM   1399 C CG2 . THR A 1 744  ? 173.037 195.940 182.408 1.00 82.04  ? 755  THR A CG2 1 
ATOM   1400 N N   . ARG A 1 745  ? 172.365 192.039 180.154 1.00 82.72  ? 756  ARG A N   1 
ATOM   1401 C CA  . ARG A 1 745  ? 172.330 190.599 179.928 1.00 82.72  ? 756  ARG A CA  1 
ATOM   1402 C C   . ARG A 1 745  ? 173.081 190.215 178.660 1.00 82.72  ? 756  ARG A C   1 
ATOM   1403 O O   . ARG A 1 745  ? 173.718 189.156 178.614 1.00 82.72  ? 756  ARG A O   1 
ATOM   1404 C CB  . ARG A 1 745  ? 170.883 190.111 179.863 1.00 82.72  ? 756  ARG A CB  1 
ATOM   1405 C CG  . ARG A 1 745  ? 170.734 188.602 179.952 1.00 82.72  ? 756  ARG A CG  1 
ATOM   1406 C CD  . ARG A 1 745  ? 169.284 188.206 180.175 1.00 82.72  ? 756  ARG A CD  1 
ATOM   1407 N NE  . ARG A 1 745  ? 168.722 188.847 181.357 1.00 82.72  ? 756  ARG A NE  1 
ATOM   1408 C CZ  . ARG A 1 745  ? 167.528 188.572 181.863 1.00 82.72  ? 756  ARG A CZ  1 
ATOM   1409 N NH1 . ARG A 1 745  ? 166.736 187.666 181.313 1.00 82.72  ? 756  ARG A NH1 1 
ATOM   1410 N NH2 . ARG A 1 745  ? 167.117 189.222 182.949 1.00 82.72  ? 756  ARG A NH2 1 
ATOM   1411 N N   . LEU A 1 746  ? 173.019 191.055 177.627 1.00 79.90  ? 757  LEU A N   1 
ATOM   1412 C CA  . LEU A 1 746  ? 173.769 190.813 176.403 1.00 79.90  ? 757  LEU A CA  1 
ATOM   1413 C C   . LEU A 1 746  ? 175.241 191.178 176.529 1.00 79.90  ? 757  LEU A C   1 
ATOM   1414 O O   . LEU A 1 746  ? 176.046 190.712 175.715 1.00 79.90  ? 757  LEU A O   1 
ATOM   1415 C CB  . LEU A 1 746  ? 173.144 191.588 175.241 1.00 79.90  ? 757  LEU A CB  1 
ATOM   1416 C CG  . LEU A 1 746  ? 171.798 191.061 174.741 1.00 79.90  ? 757  LEU A CG  1 
ATOM   1417 C CD1 . LEU A 1 746  ? 171.179 192.027 173.744 1.00 79.90  ? 757  LEU A CD1 1 
ATOM   1418 C CD2 . LEU A 1 746  ? 171.956 189.679 174.127 1.00 79.90  ? 757  LEU A CD2 1 
ATOM   1419 N N   . THR A 1 747  ? 175.616 191.989 177.519 1.00 79.52  ? 758  THR A N   1 
ATOM   1420 C CA  . THR A 1 747  ? 177.032 192.254 177.756 1.00 79.52  ? 758  THR A CA  1 
ATOM   1421 C C   . THR A 1 747  ? 177.767 191.068 178.373 1.00 79.52  ? 758  THR A C   1 
ATOM   1422 O O   . THR A 1 747  ? 178.995 191.127 178.503 1.00 79.52  ? 758  THR A O   1 
ATOM   1423 C CB  . THR A 1 747  ? 177.215 193.478 178.659 1.00 79.52  ? 758  THR A CB  1 
ATOM   1424 O OG1 . THR A 1 747  ? 176.505 193.283 179.888 1.00 79.52  ? 758  THR A OG1 1 
ATOM   1425 C CG2 . THR A 1 747  ? 176.718 194.738 177.968 1.00 79.52  ? 758  THR A CG2 1 
ATOM   1426 N N   . ARG A 1 748  ? 177.059 190.010 178.761 1.00 80.94  ? 759  ARG A N   1 
ATOM   1427 C CA  . ARG A 1 748  ? 177.697 188.860 179.386 1.00 80.94  ? 759  ARG A CA  1 
ATOM   1428 C C   . ARG A 1 748  ? 178.652 188.168 178.419 1.00 80.94  ? 759  ARG A C   1 
ATOM   1429 O O   . ARG A 1 748  ? 178.428 188.126 177.207 1.00 80.94  ? 759  ARG A O   1 
ATOM   1430 C CB  . ARG A 1 748  ? 176.647 187.865 179.877 1.00 80.94  ? 759  ARG A CB  1 
ATOM   1431 C CG  . ARG A 1 748  ? 175.790 188.373 181.024 1.00 80.94  ? 759  ARG A CG  1 
ATOM   1432 C CD  . ARG A 1 748  ? 174.918 187.262 181.585 1.00 80.94  ? 759  ARG A CD  1 
ATOM   1433 N NE  . ARG A 1 748  ? 174.030 187.739 182.637 1.00 80.94  ? 759  ARG A NE  1 
ATOM   1434 C CZ  . ARG A 1 748  ? 173.145 186.981 183.271 1.00 80.94  ? 759  ARG A CZ  1 
ATOM   1435 N NH1 . ARG A 1 748  ? 173.003 185.698 182.982 1.00 80.94  ? 759  ARG A NH1 1 
ATOM   1436 N NH2 . ARG A 1 748  ? 172.385 187.524 184.217 1.00 80.94  ? 759  ARG A NH2 1 
ATOM   1437 N N   . ASN A 1 749  ? 179.730 187.620 178.975 1.00 82.41  ? 760  ASN A N   1 
ATOM   1438 C CA  . ASN A 1 749  ? 180.748 186.964 178.169 1.00 82.41  ? 760  ASN A CA  1 
ATOM   1439 C C   . ASN A 1 749  ? 180.260 185.612 177.660 1.00 82.41  ? 760  ASN A C   1 
ATOM   1440 O O   . ASN A 1 749  ? 179.402 184.964 178.266 1.00 82.41  ? 760  ASN A O   1 
ATOM   1441 C CB  . ASN A 1 749  ? 182.031 186.780 178.979 1.00 82.41  ? 760  ASN A CB  1 
ATOM   1442 C CG  . ASN A 1 749  ? 182.509 188.070 179.614 1.00 82.41  ? 760  ASN A CG  1 
ATOM   1443 O OD1 . ASN A 1 749  ? 182.358 189.150 179.043 1.00 82.41  ? 760  ASN A OD1 1 
ATOM   1444 N ND2 . ASN A 1 749  ? 183.090 187.964 180.803 1.00 82.41  ? 760  ASN A ND2 1 
ATOM   1445 N N   . ASP A 1 750  ? 180.822 185.189 176.530 1.00 90.52  ? 761  ASP A N   1 
ATOM   1446 C CA  . ASP A 1 750  ? 180.532 183.893 175.933 1.00 90.52  ? 761  ASP A CA  1 
ATOM   1447 C C   . ASP A 1 750  ? 181.840 183.240 175.512 1.00 90.52  ? 761  ASP A C   1 
ATOM   1448 O O   . ASP A 1 750  ? 182.763 183.920 175.053 1.00 90.52  ? 761  ASP A O   1 
ATOM   1449 C CB  . ASP A 1 750  ? 179.595 184.031 174.726 1.00 90.52  ? 761  ASP A CB  1 
ATOM   1450 C CG  . ASP A 1 750  ? 179.099 182.692 174.215 1.00 90.52  ? 761  ASP A CG  1 
ATOM   1451 O OD1 . ASP A 1 750  ? 179.311 181.673 174.904 1.00 90.52  ? 761  ASP A OD1 1 
ATOM   1452 O OD2 . ASP A 1 750  ? 178.496 182.659 173.122 1.00 90.52  ? 761  ASP A OD2 1 
ATOM   1453 N N   . GLU A 1 751  ? 181.916 181.917 175.669 1.00 95.32  ? 762  GLU A N   1 
ATOM   1454 C CA  . GLU A 1 751  ? 183.146 181.194 175.370 1.00 95.32  ? 762  GLU A CA  1 
ATOM   1455 C C   . GLU A 1 751  ? 183.392 181.016 173.877 1.00 95.32  ? 762  GLU A C   1 
ATOM   1456 O O   . GLU A 1 751  ? 184.520 180.689 173.491 1.00 95.32  ? 762  GLU A O   1 
ATOM   1457 C CB  . GLU A 1 751  ? 183.140 179.824 176.058 1.00 95.32  ? 762  GLU A CB  1 
ATOM   1458 C CG  . GLU A 1 751  ? 182.219 178.787 175.431 1.00 95.32  ? 762  GLU A CG  1 
ATOM   1459 C CD  . GLU A 1 751  ? 180.750 179.089 175.654 1.00 95.32  ? 762  GLU A CD  1 
ATOM   1460 O OE1 . GLU A 1 751  ? 180.409 179.624 176.730 1.00 95.32  ? 762  GLU A OE1 1 
ATOM   1461 O OE2 . GLU A 1 751  ? 179.936 178.791 174.755 1.00 95.32  ? 762  GLU A OE2 1 
ATOM   1462 N N   . LYS A 1 752  ? 182.384 181.220 173.032 1.00 92.52  ? 763  LYS A N   1 
ATOM   1463 C CA  . LYS A 1 752  ? 182.536 181.150 171.579 1.00 92.52  ? 763  LYS A CA  1 
ATOM   1464 C C   . LYS A 1 752  ? 182.091 182.489 170.998 1.00 92.52  ? 763  LYS A C   1 
ATOM   1465 O O   . LYS A 1 752  ? 180.933 182.656 170.607 1.00 92.52  ? 763  LYS A O   1 
ATOM   1466 C CB  . LYS A 1 752  ? 181.737 179.989 170.981 1.00 92.52  ? 763  LYS A CB  1 
ATOM   1467 C CG  . LYS A 1 752  ? 181.534 178.811 171.918 1.00 92.52  ? 763  LYS A CG  1 
ATOM   1468 C CD  . LYS A 1 752  ? 180.532 177.817 171.350 1.00 92.52  ? 763  LYS A CD  1 
ATOM   1469 C CE  . LYS A 1 752  ? 179.233 178.498 170.945 1.00 92.52  ? 763  LYS A CE  1 
ATOM   1470 N NZ  . LYS A 1 752  ? 178.689 179.360 172.032 1.00 92.52  ? 763  LYS A NZ  1 
ATOM   1471 N N   . ASP A 1 753  ? 183.020 183.441 170.939 1.00 93.68  ? 764  ASP A N   1 
ATOM   1472 C CA  . ASP A 1 753  ? 182.757 184.753 170.369 1.00 93.68  ? 764  ASP A CA  1 
ATOM   1473 C C   . ASP A 1 753  ? 183.977 185.218 169.590 1.00 93.68  ? 764  ASP A C   1 
ATOM   1474 O O   . ASP A 1 753  ? 185.107 184.815 169.874 1.00 93.68  ? 764  ASP A O   1 
ATOM   1475 C CB  . ASP A 1 753  ? 182.409 185.788 171.449 1.00 93.68  ? 764  ASP A CB  1 
ATOM   1476 C CG  . ASP A 1 753  ? 180.924 185.853 171.739 1.00 93.68  ? 764  ASP A CG  1 
ATOM   1477 O OD1 . ASP A 1 753  ? 180.130 185.351 170.915 1.00 93.68  ? 764  ASP A OD1 1 
ATOM   1478 O OD2 . ASP A 1 753  ? 180.549 186.415 172.789 1.00 93.68  ? 764  ASP A OD2 1 
ATOM   1479 N N   . ASP A 1 754  ? 183.733 186.073 168.601 1.00 94.20  ? 765  ASP A N   1 
ATOM   1480 C CA  . ASP A 1 754  ? 184.821 186.671 167.845 1.00 94.20  ? 765  ASP A CA  1 
ATOM   1481 C C   . ASP A 1 754  ? 185.542 187.716 168.692 1.00 94.20  ? 765  ASP A C   1 
ATOM   1482 O O   . ASP A 1 754  ? 185.075 188.122 169.760 1.00 94.20  ? 765  ASP A O   1 
ATOM   1483 C CB  . ASP A 1 754  ? 184.295 187.307 166.558 1.00 94.20  ? 765  ASP A CB  1 
ATOM   1484 C CG  . ASP A 1 754  ? 183.464 186.347 165.731 1.00 94.20  ? 765  ASP A CG  1 
ATOM   1485 O OD1 . ASP A 1 754  ? 183.944 185.227 165.456 1.00 94.20  ? 765  ASP A OD1 1 
ATOM   1486 O OD2 . ASP A 1 754  ? 182.330 186.712 165.355 1.00 94.20  ? 765  ASP A OD2 1 
ATOM   1487 N N   . TRP A 1 755  ? 186.707 188.144 168.202 1.00 91.06  ? 766  TRP A N   1 
ATOM   1488 C CA  . TRP A 1 755  ? 187.462 189.178 168.903 1.00 91.06  ? 766  TRP A CA  1 
ATOM   1489 C C   . TRP A 1 755  ? 186.682 190.486 168.964 1.00 91.06  ? 766  TRP A C   1 
ATOM   1490 O O   . TRP A 1 755  ? 186.661 191.158 170.003 1.00 91.06  ? 766  TRP A O   1 
ATOM   1491 C CB  . TRP A 1 755  ? 188.819 189.385 168.227 1.00 91.06  ? 766  TRP A CB  1 
ATOM   1492 C CG  . TRP A 1 755  ? 188.720 189.884 166.818 1.00 91.06  ? 766  TRP A CG  1 
ATOM   1493 C CD1 . TRP A 1 755  ? 188.594 189.130 165.688 1.00 91.06  ? 766  TRP A CD1 1 
ATOM   1494 C CD2 . TRP A 1 755  ? 188.737 191.251 166.388 1.00 91.06  ? 766  TRP A CD2 1 
ATOM   1495 N NE1 . TRP A 1 755  ? 188.532 189.942 164.582 1.00 91.06  ? 766  TRP A NE1 1 
ATOM   1496 C CE2 . TRP A 1 755  ? 188.617 191.248 164.985 1.00 91.06  ? 766  TRP A CE2 1 
ATOM   1497 C CE3 . TRP A 1 755  ? 188.840 192.475 167.054 1.00 91.06  ? 766  TRP A CE3 1 
ATOM   1498 C CZ2 . TRP A 1 755  ? 188.599 192.422 164.235 1.00 91.06  ? 766  TRP A CZ2 1 
ATOM   1499 C CZ3 . TRP A 1 755  ? 188.822 193.639 166.308 1.00 91.06  ? 766  TRP A CZ3 1 
ATOM   1500 C CH2 . TRP A 1 755  ? 188.701 193.604 164.914 1.00 91.06  ? 766  TRP A CH2 1 
ATOM   1501 N N   . LEU A 1 756  ? 186.027 190.860 167.862 1.00 88.04  ? 767  LEU A N   1 
ATOM   1502 C CA  . LEU A 1 756  ? 185.239 192.088 167.851 1.00 88.04  ? 767  LEU A CA  1 
ATOM   1503 C C   . LEU A 1 756  ? 184.047 191.985 168.797 1.00 88.04  ? 767  LEU A C   1 
ATOM   1504 O O   . LEU A 1 756  ? 183.729 192.944 169.510 1.00 88.04  ? 767  LEU A O   1 
ATOM   1505 C CB  . LEU A 1 756  ? 184.802 192.413 166.418 1.00 88.04  ? 767  LEU A CB  1 
ATOM   1506 C CG  . LEU A 1 756  ? 183.568 191.788 165.754 1.00 88.04  ? 767  LEU A CG  1 
ATOM   1507 C CD1 . LEU A 1 756  ? 182.288 192.535 166.102 1.00 88.04  ? 767  LEU A CD1 1 
ATOM   1508 C CD2 . LEU A 1 756  ? 183.754 191.719 164.246 1.00 88.04  ? 767  LEU A CD2 1 
ATOM   1509 N N   . LYS A 1 757  ? 183.378 190.829 168.819 1.00 86.68  ? 768  LYS A N   1 
ATOM   1510 C CA  . LYS A 1 757  ? 182.253 190.642 169.731 1.00 86.68  ? 768  LYS A CA  1 
ATOM   1511 C C   . LYS A 1 757  ? 182.702 190.726 171.184 1.00 86.68  ? 768  LYS A C   1 
ATOM   1512 O O   . LYS A 1 757  ? 182.043 191.369 172.011 1.00 86.68  ? 768  LYS A O   1 
ATOM   1513 C CB  . LYS A 1 757  ? 181.576 189.299 169.460 1.00 86.68  ? 768  LYS A CB  1 
ATOM   1514 C CG  . LYS A 1 757  ? 180.584 189.311 168.311 1.00 86.68  ? 768  LYS A CG  1 
ATOM   1515 C CD  . LYS A 1 757  ? 179.732 188.051 168.324 1.00 86.68  ? 768  LYS A CD  1 
ATOM   1516 C CE  . LYS A 1 757  ? 178.799 187.992 167.127 1.00 86.68  ? 768  LYS A CE  1 
ATOM   1517 N NZ  . LYS A 1 757  ? 177.782 186.916 167.278 1.00 86.68  ? 768  LYS A NZ  1 
ATOM   1518 N N   . ARG A 1 758  ? 183.824 190.068 171.486 1.00 87.11  ? 769  ARG A N   1 
ATOM   1519 C CA  . ARG A 1 758  ? 184.363 190.089 172.869 1.00 87.11  ? 769  ARG A CA  1 
ATOM   1520 C C   . ARG A 1 758  ? 184.683 191.543 173.249 1.00 87.11  ? 769  ARG A C   1 
ATOM   1521 O O   . ARG A 1 758  ? 184.276 191.969 174.352 1.00 87.11  ? 769  ARG A O   1 
ATOM   1522 C CB  . ARG A 1 758  ? 185.600 189.189 172.947 1.00 87.11  ? 769  ARG A CB  1 
ATOM   1523 C CG  . ARG A 1 758  ? 185.932 188.695 174.348 1.00 87.11  ? 769  ARG A CG  1 
ATOM   1524 C CD  . ARG A 1 758  ? 187.058 187.671 174.324 1.00 87.11  ? 769  ARG A CD  1 
ATOM   1525 N NE  . ARG A 1 758  ? 186.796 186.531 173.437 1.00 87.11  ? 769  ARG A NE  1 
ATOM   1526 C CZ  . ARG A 1 758  ? 185.817 185.643 173.575 1.00 87.11  ? 769  ARG A CZ  1 
ATOM   1527 N NH1 . ARG A 1 758  ? 185.086 185.617 174.675 1.00 87.11  ? 769  ARG A NH1 1 
ATOM   1528 N NH2 . ARG A 1 758  ? 185.581 184.771 172.612 1.00 87.11  ? 769  ARG A NH2 1 
ATOM   1529 N N   . GLY A 1 759  ? 185.371 192.272 172.364 1.00 82.19  ? 770  GLY A N   1 
ATOM   1530 C CA  . GLY A 1 759  ? 185.720 193.652 172.656 1.00 82.19  ? 770  GLY A CA  1 
ATOM   1531 C C   . GLY A 1 759  ? 184.502 194.530 172.863 1.00 82.19  ? 770  GLY A C   1 
ATOM   1532 O O   . GLY A 1 759  ? 184.479 195.373 173.763 1.00 82.19  ? 770  GLY A O   1 
ATOM   1533 N N   . VAL A 1 760  ? 183.472 194.345 172.032 1.00 80.24  ? 771  VAL A N   1 
ATOM   1534 C CA  . VAL A 1 760  ? 182.246 195.125 172.176 1.00 80.24  ? 771  VAL A CA  1 
ATOM   1535 C C   . VAL A 1 760  ? 181.584 194.833 173.515 1.00 80.24  ? 771  VAL A C   1 
ATOM   1536 O O   . VAL A 1 760  ? 181.190 195.753 174.243 1.00 80.24  ? 771  VAL A O   1 
ATOM   1537 C CB  . VAL A 1 760  ? 181.294 194.845 170.997 1.00 80.24  ? 771  VAL A CB  1 
ATOM   1538 C CG1 . VAL A 1 760  ? 179.872 195.252 171.349 1.00 80.24  ? 771  VAL A CG1 1 
ATOM   1539 C CG2 . VAL A 1 760  ? 181.767 195.575 169.751 1.00 80.24  ? 771  VAL A CG2 1 
ATOM   1540 N N   . ARG A 1 761  ? 181.447 193.552 173.852 1.00 79.86  ? 772  ARG A N   1 
ATOM   1541 C CA  . ARG A 1 761  ? 180.858 193.201 175.168 1.00 79.86  ? 772  ARG A CA  1 
ATOM   1542 C C   . ARG A 1 761  ? 181.679 193.855 176.287 1.00 79.86  ? 772  ARG A C   1 
ATOM   1543 O O   . ARG A 1 761  ? 181.068 194.507 177.158 1.00 79.86  ? 772  ARG A O   1 
ATOM   1544 C CB  . ARG A 1 761  ? 180.834 191.683 175.362 1.00 79.86  ? 772  ARG A CB  1 
ATOM   1545 C CG  . ARG A 1 761  ? 179.923 190.894 174.434 1.00 79.86  ? 772  ARG A CG  1 
ATOM   1546 C CD  . ARG A 1 761  ? 180.298 189.422 174.507 1.00 79.86  ? 772  ARG A CD  1 
ATOM   1547 N NE  . ARG A 1 761  ? 179.464 188.536 173.688 1.00 79.86  ? 772  ARG A NE  1 
ATOM   1548 C CZ  . ARG A 1 761  ? 178.178 188.278 173.884 1.00 79.86  ? 772  ARG A CZ  1 
ATOM   1549 N NH1 . ARG A 1 761  ? 177.526 188.848 174.879 1.00 79.86  ? 772  ARG A NH1 1 
ATOM   1550 N NH2 . ARG A 1 761  ? 177.550 187.433 173.086 1.00 79.86  ? 772  ARG A NH2 1 
ATOM   1551 N N   . SER A 1 762  ? 183.008 193.721 176.251 1.00 79.84  ? 773  SER A N   1 
ATOM   1552 C CA  . SER A 1 762  ? 183.846 194.215 177.338 1.00 79.84  ? 773  SER A CA  1 
ATOM   1553 C C   . SER A 1 762  ? 183.729 195.726 177.491 1.00 79.84  ? 773  SER A C   1 
ATOM   1554 O O   . SER A 1 762  ? 183.515 196.229 178.601 1.00 79.84  ? 773  SER A O   1 
ATOM   1555 C CB  . SER A 1 762  ? 185.301 193.809 177.100 1.00 79.84  ? 773  SER A CB  1 
ATOM   1556 O OG  . SER A 1 762  ? 186.165 194.446 178.025 1.00 79.84  ? 773  SER A OG  1 
ATOM   1557 N N   . ASP A 1 763  ? 183.861 196.472 176.390 1.00 79.53  ? 774  ASP A N   1 
ATOM   1558 C CA  . ASP A 1 763  ? 183.857 197.926 176.511 1.00 79.53  ? 774  ASP A CA  1 
ATOM   1559 C C   . ASP A 1 763  ? 182.467 198.450 176.854 1.00 79.53  ? 774  ASP A C   1 
ATOM   1560 O O   . ASP A 1 763  ? 182.338 199.410 177.623 1.00 79.53  ? 774  ASP A O   1 
ATOM   1561 C CB  . ASP A 1 763  ? 184.409 198.584 175.240 1.00 79.53  ? 774  ASP A CB  1 
ATOM   1562 C CG  . ASP A 1 763  ? 183.646 198.205 173.985 1.00 79.53  ? 774  ASP A CG  1 
ATOM   1563 O OD1 . ASP A 1 763  ? 182.415 198.030 174.048 1.00 79.53  ? 774  ASP A OD1 1 
ATOM   1564 O OD2 . ASP A 1 763  ? 184.288 198.086 172.920 1.00 79.53  ? 774  ASP A OD2 1 
ATOM   1565 N N   . ALA A 1 764  ? 181.411 197.831 176.310 1.00 77.17  ? 775  ALA A N   1 
ATOM   1566 C CA  . ALA A 1 764  ? 180.062 198.239 176.682 1.00 77.17  ? 775  ALA A CA  1 
ATOM   1567 C C   . ALA A 1 764  ? 179.803 198.000 178.164 1.00 77.17  ? 775  ALA A C   1 
ATOM   1568 O O   . ALA A 1 764  ? 179.254 198.869 178.854 1.00 77.17  ? 775  ALA A O   1 
ATOM   1569 C CB  . ALA A 1 764  ? 179.034 197.496 175.829 1.00 77.17  ? 775  ALA A CB  1 
ATOM   1570 N N   . ALA A 1 765  ? 180.203 196.831 178.676 1.00 78.42  ? 776  ALA A N   1 
ATOM   1571 C CA  . ALA A 1 765  ? 180.015 196.548 180.094 1.00 78.42  ? 776  ALA A CA  1 
ATOM   1572 C C   . ALA A 1 765  ? 180.813 197.513 180.960 1.00 78.42  ? 776  ALA A C   1 
ATOM   1573 O O   . ALA A 1 765  ? 180.312 198.004 181.978 1.00 78.42  ? 776  ALA A O   1 
ATOM   1574 C CB  . ALA A 1 765  ? 180.406 195.103 180.398 1.00 78.42  ? 776  ALA A CB  1 
ATOM   1575 N N   . ASP A 1 766  ? 182.059 197.801 180.570 1.00 78.48  ? 777  ASP A N   1 
ATOM   1576 C CA  . ASP A 1 766  ? 182.881 198.722 181.348 1.00 78.48  ? 777  ASP A CA  1 
ATOM   1577 C C   . ASP A 1 766  ? 182.277 200.121 181.370 1.00 78.48  ? 777  ASP A C   1 
ATOM   1578 O O   . ASP A 1 766  ? 182.217 200.762 182.427 1.00 78.48  ? 777  ASP A O   1 
ATOM   1579 C CB  . ASP A 1 766  ? 184.302 198.759 180.787 1.00 78.48  ? 777  ASP A CB  1 
ATOM   1580 C CG  . ASP A 1 766  ? 185.038 197.447 180.977 1.00 78.48  ? 777  ASP A CG  1 
ATOM   1581 O OD1 . ASP A 1 766  ? 184.700 196.706 181.924 1.00 78.48  ? 777  ASP A OD1 1 
ATOM   1582 O OD2 . ASP A 1 766  ? 185.953 197.155 180.179 1.00 78.48  ? 777  ASP A OD2 1 
ATOM   1583 N N   . LEU A 1 767  ? 181.816 200.610 180.215 1.00 76.08  ? 778  LEU A N   1 
ATOM   1584 C CA  . LEU A 1 767  ? 181.222 201.942 180.168 1.00 76.08  ? 778  LEU A CA  1 
ATOM   1585 C C   . LEU A 1 767  ? 179.940 202.005 180.987 1.00 76.08  ? 778  LEU A C   1 
ATOM   1586 O O   . LEU A 1 767  ? 179.703 202.983 181.707 1.00 76.08  ? 778  LEU A O   1 
ATOM   1587 C CB  . LEU A 1 767  ? 180.956 202.353 178.721 1.00 76.08  ? 778  LEU A CB  1 
ATOM   1588 C CG  . LEU A 1 767  ? 180.247 203.698 178.546 1.00 76.08  ? 778  LEU A CG  1 
ATOM   1589 C CD1 . LEU A 1 767  ? 181.052 204.815 179.192 1.00 76.08  ? 778  LEU A CD1 1 
ATOM   1590 C CD2 . LEU A 1 767  ? 179.998 203.998 177.078 1.00 76.08  ? 778  LEU A CD2 1 
ATOM   1591 N N   . TYR A 1 768  ? 179.097 200.971 180.895 1.00 77.24  ? 779  TYR A N   1 
ATOM   1592 C CA  . TYR A 1 768  ? 177.863 200.976 181.674 1.00 77.24  ? 779  TYR A CA  1 
ATOM   1593 C C   . TYR A 1 768  ? 178.150 200.921 183.169 1.00 77.24  ? 779  TYR A C   1 
ATOM   1594 O O   . TYR A 1 768  ? 177.485 201.602 183.958 1.00 77.24  ? 779  TYR A O   1 
ATOM   1595 C CB  . TYR A 1 768  ? 176.961 199.815 181.261 1.00 77.24  ? 779  TYR A CB  1 
ATOM   1596 C CG  . TYR A 1 768  ? 175.521 200.030 181.659 1.00 77.24  ? 779  TYR A CG  1 
ATOM   1597 C CD1 . TYR A 1 768  ? 174.830 201.160 181.242 1.00 77.24  ? 779  TYR A CD1 1 
ATOM   1598 C CD2 . TYR A 1 768  ? 174.857 199.120 182.469 1.00 77.24  ? 779  TYR A CD2 1 
ATOM   1599 C CE1 . TYR A 1 768  ? 173.516 201.370 181.608 1.00 77.24  ? 779  TYR A CE1 1 
ATOM   1600 C CE2 . TYR A 1 768  ? 173.542 199.323 182.842 1.00 77.24  ? 779  TYR A CE2 1 
ATOM   1601 C CZ  . TYR A 1 768  ? 172.877 200.449 182.407 1.00 77.24  ? 779  TYR A CZ  1 
ATOM   1602 O OH  . TYR A 1 768  ? 171.568 200.657 182.774 1.00 77.24  ? 779  TYR A OH  1 
ATOM   1603 N N   . ARG A 1 769  ? 179.132 200.114 183.579 1.00 73.62  ? 780  ARG A N   1 
ATOM   1604 C CA  . ARG A 1 769  ? 179.497 200.057 184.990 1.00 73.62  ? 780  ARG A CA  1 
ATOM   1605 C C   . ARG A 1 769  ? 180.043 201.395 185.470 1.00 73.62  ? 780  ARG A C   1 
ATOM   1606 O O   . ARG A 1 769  ? 179.762 201.820 186.597 1.00 73.62  ? 780  ARG A O   1 
ATOM   1607 C CB  . ARG A 1 769  ? 180.516 198.942 185.223 1.00 73.62  ? 780  ARG A CB  1 
ATOM   1608 C CG  . ARG A 1 769  ? 180.533 198.404 186.644 1.00 73.62  ? 780  ARG A CG  1 
ATOM   1609 C CD  . ARG A 1 769  ? 181.476 197.219 186.773 1.00 73.62  ? 780  ARG A CD  1 
ATOM   1610 N NE  . ARG A 1 769  ? 181.263 196.235 185.719 1.00 73.62  ? 780  ARG A NE  1 
ATOM   1611 C CZ  . ARG A 1 769  ? 181.785 195.016 185.714 1.00 73.62  ? 780  ARG A CZ  1 
ATOM   1612 N NH1 . ARG A 1 769  ? 182.562 194.593 186.699 1.00 73.62  ? 780  ARG A NH1 1 
ATOM   1613 N NH2 . ARG A 1 769  ? 181.522 194.201 184.697 1.00 73.62  ? 780  ARG A NH2 1 
ATOM   1614 N N   . GLN A 1 770  ? 180.831 202.071 184.630 1.00 73.27  ? 781  GLN A N   1 
ATOM   1615 C CA  . GLN A 1 770  ? 181.340 203.389 184.996 1.00 73.27  ? 781  GLN A CA  1 
ATOM   1616 C C   . GLN A 1 770  ? 180.210 204.404 185.125 1.00 73.27  ? 781  GLN A C   1 
ATOM   1617 O O   . GLN A 1 770  ? 180.229 205.251 186.025 1.00 73.27  ? 781  GLN A O   1 
ATOM   1618 C CB  . GLN A 1 770  ? 182.369 203.859 183.968 1.00 73.27  ? 781  GLN A CB  1 
ATOM   1619 C CG  . GLN A 1 770  ? 183.104 205.128 184.367 1.00 73.27  ? 781  GLN A CG  1 
ATOM   1620 C CD  . GLN A 1 770  ? 182.571 206.357 183.660 1.00 73.27  ? 781  GLN A CD  1 
ATOM   1621 O OE1 . GLN A 1 770  ? 182.038 206.268 182.554 1.00 73.27  ? 781  GLN A OE1 1 
ATOM   1622 N NE2 . GLN A 1 770  ? 182.710 207.513 184.297 1.00 73.27  ? 781  GLN A NE2 1 
ATOM   1623 N N   . GLN A 1 771  ? 179.219 204.337 184.238 1.00 73.07  ? 782  GLN A N   1 
ATOM   1624 C CA  . GLN A 1 771  ? 178.113 205.294 184.244 1.00 73.07  ? 782  GLN A CA  1 
ATOM   1625 C C   . GLN A 1 771  ? 176.925 204.713 185.011 1.00 73.07  ? 782  GLN A C   1 
ATOM   1626 O O   . GLN A 1 771  ? 175.941 204.238 184.442 1.00 73.07  ? 782  GLN A O   1 
ATOM   1627 C CB  . GLN A 1 771  ? 177.730 205.670 182.816 1.00 73.07  ? 782  GLN A CB  1 
ATOM   1628 C CG  . GLN A 1 771  ? 178.762 206.525 182.101 1.00 73.07  ? 782  GLN A CG  1 
ATOM   1629 C CD  . GLN A 1 771  ? 178.785 207.955 182.603 1.00 73.07  ? 782  GLN A CD  1 
ATOM   1630 O OE1 . GLN A 1 771  ? 177.748 208.615 182.682 1.00 73.07  ? 782  GLN A OE1 1 
ATOM   1631 N NE2 . GLN A 1 771  ? 179.971 208.443 182.946 1.00 73.07  ? 782  GLN A NE2 1 
ATOM   1632 N N   . ASP A 1 772  ? 177.079 204.752 186.336 1.00 70.83  ? 783  ASP A N   1 
ATOM   1633 C CA  . ASP A 1 772  ? 175.992 204.256 187.215 1.00 70.83  ? 783  ASP A CA  1 
ATOM   1634 C C   . ASP A 1 772  ? 176.176 204.851 188.608 1.00 70.83  ? 783  ASP A C   1 
ATOM   1635 O O   . ASP A 1 772  ? 177.266 205.389 188.888 1.00 70.83  ? 783  ASP A O   1 
ATOM   1636 C CB  . ASP A 1 772  ? 175.912 202.736 187.236 1.00 70.83  ? 783  ASP A CB  1 
ATOM   1637 C CG  . ASP A 1 772  ? 177.016 201.996 187.979 1.00 70.83  ? 783  ASP A CG  1 
ATOM   1638 O OD1 . ASP A 1 772  ? 177.929 202.660 188.513 1.00 70.83  ? 783  ASP A OD1 1 
ATOM   1639 O OD2 . ASP A 1 772  ? 176.952 200.750 188.021 1.00 70.83  ? 783  ASP A OD2 1 
ATOM   1640 N N   . LEU A 1 773  ? 175.148 204.766 189.434 1.00 67.84  ? 784  LEU A N   1 
ATOM   1641 C CA  . LEU A 1 773  ? 175.162 205.243 190.810 1.00 67.84  ? 784  LEU A CA  1 
ATOM   1642 C C   . LEU A 1 773  ? 175.101 204.050 191.753 1.00 67.84  ? 784  LEU A C   1 
ATOM   1643 O O   . LEU A 1 773  ? 174.194 203.219 191.649 1.00 67.84  ? 784  LEU A O   1 
ATOM   1644 C CB  . LEU A 1 773  ? 173.987 206.188 191.074 1.00 67.84  ? 784  LEU A CB  1 
ATOM   1645 C CG  . LEU A 1 773  ? 174.131 207.210 192.205 1.00 67.84  ? 784  LEU A CG  1 
ATOM   1646 C CD1 . LEU A 1 773  ? 175.577 207.634 192.386 1.00 67.84  ? 784  LEU A CD1 1 
ATOM   1647 C CD2 . LEU A 1 773  ? 173.246 208.419 191.947 1.00 67.84  ? 784  LEU A CD2 1 
ATOM   1648 N N   . ASN A 1 774  ? 176.065 203.970 192.669 1.00 67.53  ? 785  ASN A N   1 
ATOM   1649 C CA  . ASN A 1 774  ? 176.158 202.865 193.613 1.00 67.53  ? 785  ASN A CA  1 
ATOM   1650 C C   . ASN A 1 774  ? 176.202 203.395 195.039 1.00 67.53  ? 785  ASN A C   1 
ATOM   1651 O O   . ASN A 1 774  ? 176.928 204.348 195.335 1.00 67.53  ? 785  ASN A O   1 
ATOM   1652 C CB  . ASN A 1 774  ? 177.397 201.998 193.337 1.00 67.53  ? 785  ASN A CB  1 
ATOM   1653 C CG  . ASN A 1 774  ? 177.199 201.053 192.165 1.00 67.53  ? 785  ASN A CG  1 
ATOM   1654 O OD1 . ASN A 1 774  ? 176.306 201.246 191.342 1.00 67.53  ? 785  ASN A OD1 1 
ATOM   1655 N ND2 . ASN A 1 774  ? 178.034 200.023 192.087 1.00 67.53  ? 785  ASN A ND2 1 
ATOM   1656 N N   . VAL A 1 775  ? 175.418 202.771 195.917 1.00 68.30  ? 786  VAL A N   1 
ATOM   1657 C CA  . VAL A 1 775  ? 175.397 203.094 197.339 1.00 68.30  ? 786  VAL A CA  1 
ATOM   1658 C C   . VAL A 1 775  ? 175.640 201.808 198.116 1.00 68.30  ? 786  VAL A C   1 
ATOM   1659 O O   . VAL A 1 775  ? 174.932 200.816 197.915 1.00 68.30  ? 786  VAL A O   1 
ATOM   1660 C CB  . VAL A 1 775  ? 174.062 203.737 197.763 1.00 68.30  ? 786  VAL A CB  1 
ATOM   1661 C CG1 . VAL A 1 775  ? 174.030 203.967 199.268 1.00 68.30  ? 786  VAL A CG1 1 
ATOM   1662 C CG2 . VAL A 1 775  ? 173.830 205.037 197.008 1.00 68.30  ? 786  VAL A CG2 1 
ATOM   1663 N N   . THR A 1 776  ? 176.637 201.824 199.001 1.00 69.10  ? 787  THR A N   1 
ATOM   1664 C CA  . THR A 1 776  ? 177.017 200.648 199.770 1.00 69.10  ? 787  THR A CA  1 
ATOM   1665 C C   . THR A 1 776  ? 177.075 200.979 201.255 1.00 69.10  ? 787  THR A C   1 
ATOM   1666 O O   . THR A 1 776  ? 177.449 202.087 201.649 1.00 69.10  ? 787  THR A O   1 
ATOM   1667 C CB  . THR A 1 776  ? 178.376 200.089 199.318 1.00 69.10  ? 787  THR A CB  1 
ATOM   1668 O OG1 . THR A 1 776  ? 179.420 200.976 199.738 1.00 69.10  ? 787  THR A OG1 1 
ATOM   1669 C CG2 . THR A 1 776  ? 178.425 199.922 197.804 1.00 69.10  ? 787  THR A CG2 1 
ATOM   1670 N N   . LEU A 1 777  ? 176.690 200.000 202.075 1.00 70.09  ? 788  LEU A N   1 
ATOM   1671 C CA  . LEU A 1 777  ? 176.756 200.099 203.529 1.00 70.09  ? 788  LEU A CA  1 
ATOM   1672 C C   . LEU A 1 777  ? 177.394 198.826 204.061 1.00 70.09  ? 788  LEU A C   1 
ATOM   1673 O O   . LEU A 1 777  ? 176.929 197.725 203.752 1.00 70.09  ? 788  LEU A O   1 
ATOM   1674 C CB  . LEU A 1 777  ? 175.356 200.312 204.132 1.00 70.09  ? 788  LEU A CB  1 
ATOM   1675 C CG  . LEU A 1 777  ? 175.104 200.485 205.638 1.00 70.09  ? 788  LEU A CG  1 
ATOM   1676 C CD1 . LEU A 1 777  ? 173.727 201.087 205.837 1.00 70.09  ? 788  LEU A CD1 1 
ATOM   1677 C CD2 . LEU A 1 777  ? 175.191 199.170 206.408 1.00 70.09  ? 788  LEU A CD2 1 
ATOM   1678 N N   . GLU A 1 778  ? 178.448 198.971 204.861 1.00 73.14  ? 789  GLU A N   1 
ATOM   1679 C CA  . GLU A 1 778  ? 179.179 197.811 205.351 1.00 73.14  ? 789  GLU A CA  1 
ATOM   1680 C C   . GLU A 1 778  ? 179.534 197.996 206.816 1.00 73.14  ? 789  GLU A C   1 
ATOM   1681 O O   . GLU A 1 778  ? 179.995 199.068 207.218 1.00 73.14  ? 789  GLU A O   1 
ATOM   1682 C CB  . GLU A 1 778  ? 180.453 197.574 204.535 1.00 73.14  ? 789  GLU A CB  1 
ATOM   1683 C CG  . GLU A 1 778  ? 181.324 196.450 205.077 1.00 73.14  ? 789  GLU A CG  1 
ATOM   1684 C CD  . GLU A 1 778  ? 182.517 196.166 204.194 1.00 73.14  ? 789  GLU A CD  1 
ATOM   1685 O OE1 . GLU A 1 778  ? 182.425 196.433 202.979 1.00 73.14  ? 789  GLU A OE1 1 
ATOM   1686 O OE2 . GLU A 1 778  ? 183.545 195.682 204.711 1.00 73.14  ? 789  GLU A OE2 1 
ATOM   1687 N N   . HIS A 1 779  ? 179.320 196.945 207.602 1.00 72.64  ? 790  HIS A N   1 
ATOM   1688 C CA  . HIS A 1 779  ? 179.751 196.882 208.990 1.00 72.64  ? 790  HIS A CA  1 
ATOM   1689 C C   . HIS A 1 779  ? 180.625 195.650 209.175 1.00 72.64  ? 790  HIS A C   1 
ATOM   1690 O O   . HIS A 1 779  ? 180.198 194.531 208.870 1.00 72.64  ? 790  HIS A O   1 
ATOM   1691 C CB  . HIS A 1 779  ? 178.552 196.834 209.938 1.00 72.64  ? 790  HIS A CB  1 
ATOM   1692 C CG  . HIS A 1 779  ? 178.911 197.040 211.376 1.00 72.64  ? 790  HIS A CG  1 
ATOM   1693 N ND1 . HIS A 1 779  ? 179.491 198.200 211.841 1.00 72.64  ? 790  HIS A ND1 1 
ATOM   1694 C CD2 . HIS A 1 779  ? 178.773 196.231 212.454 1.00 72.64  ? 790  HIS A CD2 1 
ATOM   1695 C CE1 . HIS A 1 779  ? 179.696 198.097 213.142 1.00 72.64  ? 790  HIS A CE1 1 
ATOM   1696 N NE2 . HIS A 1 779  ? 179.268 196.912 213.539 1.00 72.64  ? 790  HIS A NE2 1 
ATOM   1697 N N   . ASP A 1 780  ? 181.840 195.854 209.676 1.00 73.90  ? 791  ASP A N   1 
ATOM   1698 C CA  . ASP A 1 780  ? 182.813 194.782 209.834 1.00 73.90  ? 791  ASP A CA  1 
ATOM   1699 C C   . ASP A 1 780  ? 183.280 194.709 211.280 1.00 73.90  ? 791  ASP A C   1 
ATOM   1700 O O   . ASP A 1 780  ? 183.466 195.742 211.931 1.00 73.90  ? 791  ASP A O   1 
ATOM   1701 C CB  . ASP A 1 780  ? 184.010 194.980 208.898 1.00 73.90  ? 791  ASP A CB  1 
ATOM   1702 C CG  . ASP A 1 780  ? 184.738 196.285 209.146 1.00 73.90  ? 791  ASP A CG  1 
ATOM   1703 O OD1 . ASP A 1 780  ? 184.115 197.219 209.689 1.00 73.90  ? 791  ASP A OD1 1 
ATOM   1704 O OD2 . ASP A 1 780  ? 185.933 196.379 208.794 1.00 73.90  ? 791  ASP A OD2 1 
ATOM   1705 N N   . TYR A 1 781  ? 183.463 193.488 211.774 1.00 73.47  ? 792  TYR A N   1 
ATOM   1706 C CA  . TYR A 1 781  ? 183.958 193.246 213.122 1.00 73.47  ? 792  TYR A CA  1 
ATOM   1707 C C   . TYR A 1 781  ? 185.406 192.784 213.029 1.00 73.47  ? 792  TYR A C   1 
ATOM   1708 O O   . TYR A 1 781  ? 185.699 191.780 212.371 1.00 73.47  ? 792  TYR A O   1 
ATOM   1709 C CB  . TYR A 1 781  ? 183.104 192.198 213.836 1.00 73.47  ? 792  TYR A CB  1 
ATOM   1710 C CG  . TYR A 1 781  ? 181.646 192.576 213.972 1.00 73.47  ? 792  TYR A CG  1 
ATOM   1711 C CD1 . TYR A 1 781  ? 181.178 193.224 215.106 1.00 73.47  ? 792  TYR A CD1 1 
ATOM   1712 C CD2 . TYR A 1 781  ? 180.736 192.280 212.965 1.00 73.47  ? 792  TYR A CD2 1 
ATOM   1713 C CE1 . TYR A 1 781  ? 179.847 193.570 215.235 1.00 73.47  ? 792  TYR A CE1 1 
ATOM   1714 C CE2 . TYR A 1 781  ? 179.403 192.622 213.084 1.00 73.47  ? 792  TYR A CE2 1 
ATOM   1715 C CZ  . TYR A 1 781  ? 178.964 193.266 214.221 1.00 73.47  ? 792  TYR A CZ  1 
ATOM   1716 O OH  . TYR A 1 781  ? 177.637 193.609 214.346 1.00 73.47  ? 792  TYR A OH  1 
ATOM   1717 N N   . TRP A 1 782  ? 186.308 193.511 213.685 1.00 70.69  ? 793  TRP A N   1 
ATOM   1718 C CA  . TRP A 1 782  ? 187.726 193.193 213.631 1.00 70.69  ? 793  TRP A CA  1 
ATOM   1719 C C   . TRP A 1 782  ? 188.354 193.409 214.999 1.00 70.69  ? 793  TRP A C   1 
ATOM   1720 O O   . TRP A 1 782  ? 187.922 194.268 215.772 1.00 70.69  ? 793  TRP A O   1 
ATOM   1721 C CB  . TRP A 1 782  ? 188.453 194.035 212.574 1.00 70.69  ? 793  TRP A CB  1 
ATOM   1722 C CG  . TRP A 1 782  ? 188.394 195.512 212.819 1.00 70.69  ? 793  TRP A CG  1 
ATOM   1723 C CD1 . TRP A 1 782  ? 187.316 196.329 212.645 1.00 70.69  ? 793  TRP A CD1 1 
ATOM   1724 C CD2 . TRP A 1 782  ? 189.466 196.350 213.266 1.00 70.69  ? 793  TRP A CD2 1 
ATOM   1725 N NE1 . TRP A 1 782  ? 187.647 197.624 212.965 1.00 70.69  ? 793  TRP A NE1 1 
ATOM   1726 C CE2 . TRP A 1 782  ? 188.962 197.663 213.348 1.00 70.69  ? 793  TRP A CE2 1 
ATOM   1727 C CE3 . TRP A 1 782  ? 190.801 196.118 213.608 1.00 70.69  ? 793  TRP A CE3 1 
ATOM   1728 C CZ2 . TRP A 1 782  ? 189.746 198.739 213.758 1.00 70.69  ? 793  TRP A CZ2 1 
ATOM   1729 C CZ3 . TRP A 1 782  ? 191.578 197.187 214.015 1.00 70.69  ? 793  TRP A CZ3 1 
ATOM   1730 C CH2 . TRP A 1 782  ? 191.048 198.481 214.087 1.00 70.69  ? 793  TRP A CH2 1 
ATOM   1731 N N   . GLY A 1 783  ? 189.381 192.618 215.286 1.00 70.54  ? 794  GLY A N   1 
ATOM   1732 C CA  . GLY A 1 783  ? 190.069 192.712 216.559 1.00 70.54  ? 794  GLY A CA  1 
ATOM   1733 C C   . GLY A 1 783  ? 191.151 191.660 216.645 1.00 70.54  ? 794  GLY A C   1 
ATOM   1734 O O   . GLY A 1 783  ? 191.374 190.883 215.711 1.00 70.54  ? 794  GLY A O   1 
ATOM   1735 N N   . SER A 1 784  ? 191.827 191.645 217.792 1.00 71.20  ? 795  SER A N   1 
ATOM   1736 C CA  . SER A 1 784  ? 192.909 190.700 218.025 1.00 71.20  ? 795  SER A CA  1 
ATOM   1737 C C   . SER A 1 784  ? 193.022 190.420 219.515 1.00 71.20  ? 795  SER A C   1 
ATOM   1738 O O   . SER A 1 784  ? 192.803 191.304 220.348 1.00 71.20  ? 795  SER A O   1 
ATOM   1739 C CB  . SER A 1 784  ? 194.243 191.227 217.483 1.00 71.20  ? 795  SER A CB  1 
ATOM   1740 O OG  . SER A 1 784  ? 194.600 192.449 218.105 1.00 71.20  ? 795  SER A OG  1 
ATOM   1741 N N   . SER A 1 785  ? 193.367 189.177 219.841 1.00 75.32  ? 796  SER A N   1 
ATOM   1742 C CA  . SER A 1 785  ? 193.537 188.783 221.231 1.00 75.32  ? 796  SER A CA  1 
ATOM   1743 C C   . SER A 1 785  ? 194.803 189.400 221.816 1.00 75.32  ? 796  SER A C   1 
ATOM   1744 O O   . SER A 1 785  ? 195.806 189.593 221.124 1.00 75.32  ? 796  SER A O   1 
ATOM   1745 C CB  . SER A 1 785  ? 193.594 187.261 221.353 1.00 75.32  ? 796  SER A CB  1 
ATOM   1746 O OG  . SER A 1 785  ? 194.611 186.721 220.526 1.00 75.32  ? 796  SER A OG  1 
ATOM   1747 N N   . GLY A 1 786  ? 194.746 189.711 223.104 1.00 70.26  ? 797  GLY A N   1 
ATOM   1748 C CA  . GLY A 1 786  ? 195.893 190.289 223.774 1.00 70.26  ? 797  GLY A CA  1 
ATOM   1749 C C   . GLY A 1 786  ? 195.576 190.591 225.221 1.00 70.26  ? 797  GLY A C   1 
ATOM   1750 O O   . GLY A 1 786  ? 194.491 190.280 225.718 1.00 70.26  ? 797  GLY A O   1 
ATOM   1751 N N   . THR A 1 787  ? 196.547 191.203 225.893 1.00 67.30  ? 798  THR A N   1 
ATOM   1752 C CA  . THR A 1 787  ? 196.374 191.573 227.291 1.00 67.30  ? 798  THR A CA  1 
ATOM   1753 C C   . THR A 1 787  ? 195.299 192.644 227.420 1.00 67.30  ? 798  THR A C   1 
ATOM   1754 O O   . THR A 1 787  ? 195.283 193.619 226.662 1.00 67.30  ? 798  THR A O   1 
ATOM   1755 C CB  . THR A 1 787  ? 197.693 192.074 227.877 1.00 67.30  ? 798  THR A CB  1 
ATOM   1756 O OG1 . THR A 1 787  ? 198.732 191.126 227.598 1.00 67.30  ? 798  THR A OG1 1 
ATOM   1757 C CG2 . THR A 1 787  ? 197.575 192.257 229.383 1.00 67.30  ? 798  THR A CG2 1 
ATOM   1758 N N   . GLY A 1 788  ? 194.394 192.455 228.377 1.00 66.05  ? 799  GLY A N   1 
ATOM   1759 C CA  . GLY A 1 788  ? 193.313 193.394 228.599 1.00 66.05  ? 799  GLY A CA  1 
ATOM   1760 C C   . GLY A 1 788  ? 193.779 194.782 228.982 1.00 66.05  ? 799  GLY A C   1 
ATOM   1761 O O   . GLY A 1 788  ? 194.652 194.937 229.841 1.00 66.05  ? 799  GLY A O   1 
ATOM   1762 N N   . GLY A 1 789  ? 193.205 195.801 228.348 1.00 67.47  ? 800  GLY A N   1 
ATOM   1763 C CA  . GLY A 1 789  ? 193.522 197.172 228.690 1.00 67.47  ? 800  GLY A CA  1 
ATOM   1764 C C   . GLY A 1 789  ? 194.147 197.971 227.566 1.00 67.47  ? 800  GLY A C   1 
ATOM   1765 O O   . GLY A 1 789  ? 193.813 199.145 227.382 1.00 67.47  ? 800  GLY A O   1 
ATOM   1766 N N   . TYR A 1 790  ? 195.063 197.361 226.814 1.00 62.64  ? 801  TYR A N   1 
ATOM   1767 C CA  . TYR A 1 790  ? 195.699 198.073 225.712 1.00 62.64  ? 801  TYR A CA  1 
ATOM   1768 C C   . TYR A 1 790  ? 195.788 197.222 224.451 1.00 62.64  ? 801  TYR A C   1 
ATOM   1769 O O   . TYR A 1 790  ? 196.067 197.745 223.367 1.00 62.64  ? 801  TYR A O   1 
ATOM   1770 C CB  . TYR A 1 790  ? 197.095 198.553 226.120 1.00 62.64  ? 801  TYR A CB  1 
ATOM   1771 C CG  . TYR A 1 790  ? 197.973 197.489 226.743 1.00 62.64  ? 801  TYR A CG  1 
ATOM   1772 C CD1 . TYR A 1 790  ? 198.749 196.651 225.952 1.00 62.64  ? 801  TYR A CD1 1 
ATOM   1773 C CD2 . TYR A 1 790  ? 198.036 197.331 228.121 1.00 62.64  ? 801  TYR A CD2 1 
ATOM   1774 C CE1 . TYR A 1 790  ? 199.556 195.682 226.515 1.00 62.64  ? 801  TYR A CE1 1 
ATOM   1775 C CE2 . TYR A 1 790  ? 198.841 196.364 228.693 1.00 62.64  ? 801  TYR A CE2 1 
ATOM   1776 C CZ  . TYR A 1 790  ? 199.599 195.543 227.885 1.00 62.64  ? 801  TYR A CZ  1 
ATOM   1777 O OH  . TYR A 1 790  ? 200.401 194.579 228.451 1.00 62.64  ? 801  TYR A OH  1 
ATOM   1778 N N   . SER A 1 791  ? 195.553 195.914 224.571 1.00 65.00  ? 802  SER A N   1 
ATOM   1779 C CA  . SER A 1 791  ? 195.737 195.007 223.447 1.00 65.00  ? 802  SER A CA  1 
ATOM   1780 C C   . SER A 1 791  ? 194.593 194.030 223.217 1.00 65.00  ? 802  SER A C   1 
ATOM   1781 O O   . SER A 1 791  ? 194.624 193.310 222.214 1.00 65.00  ? 802  SER A O   1 
ATOM   1782 C CB  . SER A 1 791  ? 197.037 194.205 223.613 1.00 65.00  ? 802  SER A CB  1 
ATOM   1783 O OG  . SER A 1 791  ? 197.098 193.598 224.891 1.00 65.00  ? 802  SER A OG  1 
ATOM   1784 N N   . ASP A 1 792  ? 193.593 193.973 224.099 1.00 67.60  ? 803  ASP A N   1 
ATOM   1785 C CA  . ASP A 1 792  ? 192.437 193.098 223.896 1.00 67.60  ? 803  ASP A CA  1 
ATOM   1786 C C   . ASP A 1 792  ? 191.460 193.785 222.940 1.00 67.60  ? 803  ASP A C   1 
ATOM   1787 O O   . ASP A 1 792  ? 190.352 194.190 223.297 1.00 67.60  ? 803  ASP A O   1 
ATOM   1788 C CB  . ASP A 1 792  ? 191.781 192.757 225.227 1.00 67.60  ? 803  ASP A CB  1 
ATOM   1789 C CG  . ASP A 1 792  ? 190.693 191.710 225.089 1.00 67.60  ? 803  ASP A CG  1 
ATOM   1790 O OD1 . ASP A 1 792  ? 190.806 190.848 224.192 1.00 67.60  ? 803  ASP A OD1 1 
ATOM   1791 O OD2 . ASP A 1 792  ? 189.725 191.750 225.877 1.00 67.60  ? 803  ASP A OD2 1 
ATOM   1792 N N   . LEU A 1 793  ? 191.896 193.899 221.688 1.00 65.90  ? 804  LEU A N   1 
ATOM   1793 C CA  . LEU A 1 793  ? 191.197 194.711 220.703 1.00 65.90  ? 804  LEU A CA  1 
ATOM   1794 C C   . LEU A 1 793  ? 189.925 194.023 220.223 1.00 65.90  ? 804  LEU A C   1 
ATOM   1795 O O   . LEU A 1 793  ? 189.956 192.867 219.791 1.00 65.90  ? 804  LEU A O   1 
ATOM   1796 C CB  . LEU A 1 793  ? 192.115 195.004 219.517 1.00 65.90  ? 804  LEU A CB  1 
ATOM   1797 C CG  . LEU A 1 793  ? 191.550 195.921 218.433 1.00 65.90  ? 804  LEU A CG  1 
ATOM   1798 C CD1 . LEU A 1 793  ? 191.195 197.277 219.017 1.00 65.90  ? 804  LEU A CD1 1 
ATOM   1799 C CD2 . LEU A 1 793  ? 192.542 196.068 217.292 1.00 65.90  ? 804  LEU A CD2 1 
ATOM   1800 N N   . LYS A 1 794  ? 188.807 194.746 220.301 1.00 66.42  ? 805  LYS A N   1 
ATOM   1801 C CA  . LYS A 1 794  ? 187.535 194.303 219.730 1.00 66.42  ? 805  LYS A CA  1 
ATOM   1802 C C   . LYS A 1 794  ? 186.849 195.554 219.187 1.00 66.42  ? 805  LYS A C   1 
ATOM   1803 O O   . LYS A 1 794  ? 186.254 196.317 219.953 1.00 66.42  ? 805  LYS A O   1 
ATOM   1804 C CB  . LYS A 1 794  ? 186.670 193.593 220.763 1.00 66.42  ? 805  LYS A CB  1 
ATOM   1805 C CG  . LYS A 1 794  ? 187.179 192.223 221.185 1.00 66.42  ? 805  LYS A CG  1 
ATOM   1806 C CD  . LYS A 1 794  ? 186.363 191.662 222.338 1.00 66.42  ? 805  LYS A CD  1 
ATOM   1807 C CE  . LYS A 1 794  ? 186.846 190.277 222.734 1.00 66.42  ? 805  LYS A CE  1 
ATOM   1808 N NZ  . LYS A 1 794  ? 188.297 190.270 223.068 1.00 66.42  ? 805  LYS A NZ  1 
ATOM   1809 N N   . ALA A 1 795  ? 186.935 195.757 217.875 1.00 68.74  ? 806  ALA A N   1 
ATOM   1810 C CA  . ALA A 1 795  ? 186.493 196.996 217.254 1.00 68.74  ? 806  ALA A CA  1 
ATOM   1811 C C   . ALA A 1 795  ? 185.431 196.730 216.196 1.00 68.74  ? 806  ALA A C   1 
ATOM   1812 O O   . ALA A 1 795  ? 185.433 195.696 215.522 1.00 68.74  ? 806  ALA A O   1 
ATOM   1813 C CB  . ALA A 1 795  ? 187.672 197.747 216.624 1.00 68.74  ? 806  ALA A CB  1 
ATOM   1814 N N   . HIS A 1 796  ? 184.517 197.690 216.061 1.00 70.08  ? 807  HIS A N   1 
ATOM   1815 C CA  . HIS A 1 796  ? 183.462 197.655 215.057 1.00 70.08  ? 807  HIS A CA  1 
ATOM   1816 C C   . HIS A 1 796  ? 183.539 198.928 214.228 1.00 70.08  ? 807  HIS A C   1 
ATOM   1817 O O   . HIS A 1 796  ? 183.760 200.013 214.775 1.00 70.08  ? 807  HIS A O   1 
ATOM   1818 C CB  . HIS A 1 796  ? 182.075 197.531 215.700 1.00 70.08  ? 807  HIS A CB  1 
ATOM   1819 C CG  . HIS A 1 796  ? 182.007 196.532 216.813 1.00 70.08  ? 807  HIS A CG  1 
ATOM   1820 N ND1 . HIS A 1 796  ? 182.748 195.370 216.819 1.00 70.08  ? 807  HIS A ND1 1 
ATOM   1821 C CD2 . HIS A 1 796  ? 181.282 196.521 217.956 1.00 70.08  ? 807  HIS A CD2 1 
ATOM   1822 C CE1 . HIS A 1 796  ? 182.484 194.687 217.919 1.00 70.08  ? 807  HIS A CE1 1 
ATOM   1823 N NE2 . HIS A 1 796  ? 181.597 195.364 218.626 1.00 70.08  ? 807  HIS A NE2 1 
ATOM   1824 N N   . THR A 1 797  ? 183.359 198.796 212.917 1.00 72.31  ? 808  THR A N   1 
ATOM   1825 C CA  . THR A 1 797  ? 183.411 199.926 212.000 1.00 72.31  ? 808  THR A CA  1 
ATOM   1826 C C   . THR A 1 797  ? 182.246 199.858 211.023 1.00 72.31  ? 808  THR A C   1 
ATOM   1827 O O   . THR A 1 797  ? 181.931 198.790 210.491 1.00 72.31  ? 808  THR A O   1 
ATOM   1828 C CB  . THR A 1 797  ? 184.738 199.954 211.230 1.00 72.31  ? 808  THR A CB  1 
ATOM   1829 O OG1 . THR A 1 797  ? 185.831 199.961 212.157 1.00 72.31  ? 808  THR A OG1 1 
ATOM   1830 C CG2 . THR A 1 797  ? 184.823 201.190 210.348 1.00 72.31  ? 808  THR A CG2 1 
ATOM   1831 N N   . THR A 1 798  ? 181.605 201.004 210.796 1.00 71.46  ? 809  THR A N   1 
ATOM   1832 C CA  . THR A 1 798  ? 180.516 201.127 209.833 1.00 71.46  ? 809  THR A CA  1 
ATOM   1833 C C   . THR A 1 798  ? 180.912 202.163 208.793 1.00 71.46  ? 809  THR A C   1 
ATOM   1834 O O   . THR A 1 798  ? 181.286 203.286 209.147 1.00 71.46  ? 809  THR A O   1 
ATOM   1835 C CB  . THR A 1 798  ? 179.207 201.530 210.519 1.00 71.46  ? 809  THR A CB  1 
ATOM   1836 O OG1 . THR A 1 798  ? 178.823 200.515 211.455 1.00 71.46  ? 809  THR A OG1 1 
ATOM   1837 C CG2 . THR A 1 798  ? 178.100 201.712 209.492 1.00 71.46  ? 809  THR A CG2 1 
ATOM   1838 N N   . MET A 1 799  ? 180.828 201.791 207.518 1.00 70.70  ? 810  MET A N   1 
ATOM   1839 C CA  . MET A 1 799  ? 181.239 202.653 206.420 1.00 70.70  ? 810  MET A CA  1 
ATOM   1840 C C   . MET A 1 799  ? 180.104 202.812 205.418 1.00 70.70  ? 810  MET A C   1 
ATOM   1841 O O   . MET A 1 799  ? 179.393 201.850 205.110 1.00 70.70  ? 810  MET A O   1 
ATOM   1842 C CB  . MET A 1 799  ? 182.481 202.094 205.716 1.00 70.70  ? 810  MET A CB  1 
ATOM   1843 C CG  . MET A 1 799  ? 182.376 200.626 205.340 1.00 70.70  ? 810  MET A CG  1 
ATOM   1844 S SD  . MET A 1 799  ? 183.986 199.838 205.153 1.00 70.70  ? 810  MET A SD  1 
ATOM   1845 C CE  . MET A 1 799  ? 184.712 200.169 206.756 1.00 70.70  ? 810  MET A CE  1 
ATOM   1846 N N   . LEU A 1 800  ? 179.939 204.034 204.917 1.00 64.60  ? 811  LEU A N   1 
ATOM   1847 C CA  . LEU A 1 800  ? 178.968 204.348 203.877 1.00 64.60  ? 811  LEU A CA  1 
ATOM   1848 C C   . LEU A 1 800  ? 179.692 205.023 202.722 1.00 64.60  ? 811  LEU A C   1 
ATOM   1849 O O   . LEU A 1 800  ? 180.400 206.015 202.924 1.00 64.60  ? 811  LEU A O   1 
ATOM   1850 C CB  . LEU A 1 800  ? 177.857 205.254 204.414 1.00 64.60  ? 811  LEU A CB  1 
ATOM   1851 C CG  . LEU A 1 800  ? 176.909 205.863 203.378 1.00 64.60  ? 811  LEU A CG  1 
ATOM   1852 C CD1 . LEU A 1 800  ? 176.026 204.791 202.762 1.00 64.60  ? 811  LEU A CD1 1 
ATOM   1853 C CD2 . LEU A 1 800  ? 176.067 206.964 204.001 1.00 64.60  ? 811  LEU A CD2 1 
ATOM   1854 N N   . GLN A 1 801  ? 179.515 204.487 201.515 1.00 64.06  ? 812  GLN A N   1 
ATOM   1855 C CA  . GLN A 1 801  ? 180.214 204.978 200.336 1.00 64.06  ? 812  GLN A CA  1 
ATOM   1856 C C   . GLN A 1 801  ? 179.250 205.103 199.166 1.00 64.06  ? 812  GLN A C   1 
ATOM   1857 O O   . GLN A 1 801  ? 178.437 204.208 198.921 1.00 64.06  ? 812  GLN A O   1 
ATOM   1858 C CB  . GLN A 1 801  ? 181.376 204.051 199.959 1.00 64.06  ? 812  GLN A CB  1 
ATOM   1859 C CG  . GLN A 1 801  ? 182.228 204.548 198.805 1.00 64.06  ? 812  GLN A CG  1 
ATOM   1860 C CD  . GLN A 1 801  ? 182.995 203.429 198.128 1.00 64.06  ? 812  GLN A CD  1 
ATOM   1861 O OE1 . GLN A 1 801  ? 182.413 202.582 197.451 1.00 64.06  ? 812  GLN A OE1 1 
ATOM   1862 N NE2 . GLN A 1 801  ? 184.311 203.422 198.307 1.00 64.06  ? 812  GLN A NE2 1 
ATOM   1863 N N   . VAL A 1 802  ? 179.378 206.235 198.456 1.00 64.21  ? 813  VAL A N   1 
ATOM   1864 C CA  . VAL A 1 802  ? 178.536 206.508 197.254 1.00 64.21  ? 813  VAL A CA  1 
ATOM   1865 C C   . VAL A 1 802  ? 179.474 206.804 196.072 1.00 64.21  ? 813  VAL A C   1 
ATOM   1866 O O   . VAL A 1 802  ? 180.293 207.737 196.192 1.00 64.21  ? 813  VAL A O   1 
ATOM   1867 C CB  . VAL A 1 802  ? 177.574 207.680 197.520 1.00 64.21  ? 813  VAL A CB  1 
ATOM   1868 C CG1 . VAL A 1 802  ? 176.354 207.235 198.316 1.00 64.21  ? 813  VAL A CG1 1 
ATOM   1869 C CG2 . VAL A 1 802  ? 178.268 208.843 198.217 1.00 64.21  ? 813  VAL A CG2 1 
ATOM   1870 N N   . ASP A 1 803  ? 179.374 206.039 194.986 1.00 66.65  ? 814  ASP A N   1 
ATOM   1871 C CA  . ASP A 1 803  ? 180.234 206.180 193.814 1.00 66.65  ? 814  ASP A CA  1 
ATOM   1872 C C   . ASP A 1 803  ? 179.428 206.836 192.700 1.00 66.65  ? 814  ASP A C   1 
ATOM   1873 O O   . ASP A 1 803  ? 178.456 206.255 192.205 1.00 66.65  ? 814  ASP A O   1 
ATOM   1874 C CB  . ASP A 1 803  ? 180.781 204.827 193.360 1.00 66.65  ? 814  ASP A CB  1 
ATOM   1875 C CG  . ASP A 1 803  ? 181.410 204.036 194.491 1.00 66.65  ? 814  ASP A CG  1 
ATOM   1876 O OD1 . ASP A 1 803  ? 181.213 204.403 195.666 1.00 66.65  ? 814  ASP A OD1 1 
ATOM   1877 O OD2 . ASP A 1 803  ? 182.106 203.040 194.201 1.00 66.65  ? 814  ASP A OD2 1 
ATOM   1878 N N   . ALA A 1 804  ? 179.837 208.039 192.300 1.00 65.45  ? 815  ALA A N   1 
ATOM   1879 C CA  . ALA A 1 804  ? 179.165 208.759 191.233 1.00 65.45  ? 815  ALA A CA  1 
ATOM   1880 C C   . ALA A 1 804  ? 180.105 208.968 190.049 1.00 65.45  ? 815  ALA A C   1 
ATOM   1881 O O   . ALA A 1 804  ? 181.288 209.269 190.233 1.00 65.45  ? 815  ALA A O   1 
ATOM   1882 C CB  . ALA A 1 804  ? 178.654 210.121 191.717 1.00 65.45  ? 815  ALA A CB  1 
ATOM   1883 N N   . PRO A 1 805  ? 179.610 208.816 188.822 1.00 66.14  ? 816  PRO A N   1 
ATOM   1884 C CA  . PRO A 1 805  ? 180.472 209.010 187.651 1.00 66.14  ? 816  PRO A CA  1 
ATOM   1885 C C   . PRO A 1 805  ? 180.845 210.472 187.462 1.00 66.14  ? 816  PRO A C   1 
ATOM   1886 O O   . PRO A 1 805  ? 180.085 211.380 187.807 1.00 66.14  ? 816  PRO A O   1 
ATOM   1887 C CB  . PRO A 1 805  ? 179.609 208.501 186.491 1.00 66.14  ? 816  PRO A CB  1 
ATOM   1888 C CG  . PRO A 1 805  ? 178.210 208.723 186.948 1.00 66.14  ? 816  PRO A CG  1 
ATOM   1889 C CD  . PRO A 1 805  ? 178.210 208.552 188.446 1.00 66.14  ? 816  PRO A CD  1 
ATOM   1890 N N   . TYR A 1 806  ? 182.034 210.690 186.903 1.00 68.64  ? 817  TYR A N   1 
ATOM   1891 C CA  . TYR A 1 806  ? 182.517 212.041 186.632 1.00 68.64  ? 817  TYR A CA  1 
ATOM   1892 C C   . TYR A 1 806  ? 183.614 211.954 185.585 1.00 68.64  ? 817  TYR A C   1 
ATOM   1893 O O   . TYR A 1 806  ? 184.662 211.352 185.841 1.00 68.64  ? 817  TYR A O   1 
ATOM   1894 C CB  . TYR A 1 806  ? 183.036 212.706 187.909 1.00 68.64  ? 817  TYR A CB  1 
ATOM   1895 C CG  . TYR A 1 806  ? 183.540 214.118 187.707 1.00 68.64  ? 817  TYR A CG  1 
ATOM   1896 C CD1 . TYR A 1 806  ? 184.879 214.367 187.428 1.00 68.64  ? 817  TYR A CD1 1 
ATOM   1897 C CD2 . TYR A 1 806  ? 182.677 215.202 187.793 1.00 68.64  ? 817  TYR A CD2 1 
ATOM   1898 C CE1 . TYR A 1 806  ? 185.342 215.655 187.243 1.00 68.64  ? 817  TYR A CE1 1 
ATOM   1899 C CE2 . TYR A 1 806  ? 183.132 216.494 187.608 1.00 68.64  ? 817  TYR A CE2 1 
ATOM   1900 C CZ  . TYR A 1 806  ? 184.465 216.714 187.334 1.00 68.64  ? 817  TYR A CZ  1 
ATOM   1901 O OH  . TYR A 1 806  ? 184.922 217.999 187.150 1.00 68.64  ? 817  TYR A OH  1 
ATOM   1902 N N   . SER A 1 807  ? 183.375 212.554 184.421 1.00 73.21  ? 818  SER A N   1 
ATOM   1903 C CA  . SER A 1 807  ? 184.321 212.559 183.295 1.00 73.21  ? 818  SER A CA  1 
ATOM   1904 C C   . SER A 1 807  ? 184.609 211.104 182.931 1.00 73.21  ? 818  SER A C   1 
ATOM   1905 O O   . SER A 1 807  ? 183.658 210.330 182.736 1.00 73.21  ? 818  SER A O   1 
ATOM   1906 C CB  . SER A 1 807  ? 185.536 213.404 183.658 1.00 73.21  ? 818  SER A CB  1 
ATOM   1907 O OG  . SER A 1 807  ? 186.479 213.420 182.600 1.00 73.21  ? 818  SER A OG  1 
ATOM   1908 N N   . ASP A 1 808  ? 185.870 210.688 182.829 1.00 71.57  ? 819  ASP A N   1 
ATOM   1909 C CA  . ASP A 1 808  ? 186.192 209.309 182.486 1.00 71.57  ? 819  ASP A CA  1 
ATOM   1910 C C   . ASP A 1 808  ? 186.185 208.385 183.696 1.00 71.57  ? 819  ASP A C   1 
ATOM   1911 O O   . ASP A 1 808  ? 185.871 207.197 183.557 1.00 71.57  ? 819  ASP A O   1 
ATOM   1912 C CB  . ASP A 1 808  ? 187.559 209.246 181.797 1.00 71.57  ? 819  ASP A CB  1 
ATOM   1913 C CG  . ASP A 1 808  ? 187.853 207.883 181.197 1.00 71.57  ? 819  ASP A CG  1 
ATOM   1914 O OD1 . ASP A 1 808  ? 188.169 206.945 181.960 1.00 71.57  ? 819  ASP A OD1 1 
ATOM   1915 O OD2 . ASP A 1 808  ? 187.769 207.749 179.958 1.00 71.57  ? 819  ASP A OD2 1 
ATOM   1916 N N   . GLY A 1 809  ? 186.514 208.902 184.880 1.00 69.45  ? 820  GLY A N   1 
ATOM   1917 C CA  . GLY A 1 809  ? 186.607 208.106 186.078 1.00 69.45  ? 820  GLY A CA  1 
ATOM   1918 C C   . GLY A 1 809  ? 185.341 208.134 186.913 1.00 69.45  ? 820  GLY A C   1 
ATOM   1919 O O   . GLY A 1 809  ? 184.268 208.546 186.468 1.00 69.45  ? 820  GLY A O   1 
ATOM   1920 N N   . ARG A 1 810  ? 185.486 207.678 188.156 1.00 65.55  ? 821  ARG A N   1 
ATOM   1921 C CA  . ARG A 1 810  ? 184.385 207.592 189.107 1.00 65.55  ? 821  ARG A CA  1 
ATOM   1922 C C   . ARG A 1 810  ? 184.751 208.366 190.365 1.00 65.55  ? 821  ARG A C   1 
ATOM   1923 O O   . ARG A 1 810  ? 185.843 208.183 190.914 1.00 65.55  ? 821  ARG A O   1 
ATOM   1924 C CB  . ARG A 1 810  ? 184.068 206.135 189.448 1.00 65.55  ? 821  ARG A CB  1 
ATOM   1925 C CG  . ARG A 1 810  ? 183.097 205.470 188.489 1.00 65.55  ? 821  ARG A CG  1 
ATOM   1926 C CD  . ARG A 1 810  ? 181.657 205.709 188.915 1.00 65.55  ? 821  ARG A CD  1 
ATOM   1927 N NE  . ARG A 1 810  ? 181.223 204.773 189.945 1.00 65.55  ? 821  ARG A NE  1 
ATOM   1928 C CZ  . ARG A 1 810  ? 180.928 203.498 189.726 1.00 65.55  ? 821  ARG A CZ  1 
ATOM   1929 N NH1 . ARG A 1 810  ? 180.999 202.970 188.515 1.00 65.55  ? 821  ARG A NH1 1 
ATOM   1930 N NH2 . ARG A 1 810  ? 180.549 202.735 190.747 1.00 65.55  ? 821  ARG A NH2 1 
ATOM   1931 N N   . MET A 1 811  ? 183.843 209.227 190.815 1.00 63.78  ? 822  MET A N   1 
ATOM   1932 C CA  . MET A 1 811  ? 184.042 209.964 192.052 1.00 63.78  ? 822  MET A CA  1 
ATOM   1933 C C   . MET A 1 811  ? 183.322 209.269 193.202 1.00 63.78  ? 822  MET A C   1 
ATOM   1934 O O   . MET A 1 811  ? 182.171 208.841 193.075 1.00 63.78  ? 822  MET A O   1 
ATOM   1935 C CB  . MET A 1 811  ? 183.539 211.401 191.906 1.00 63.78  ? 822  MET A CB  1 
ATOM   1936 C CG  . MET A 1 811  ? 183.771 212.273 193.129 1.00 63.78  ? 822  MET A CG  1 
ATOM   1937 S SD  . MET A 1 811  ? 183.276 213.994 192.901 1.00 63.78  ? 822  MET A SD  1 
ATOM   1938 C CE  . MET A 1 811  ? 184.648 214.639 191.947 1.00 63.78  ? 822  MET A CE  1 
ATOM   1939 N N   . PHE A 1 812  ? 184.012 209.161 194.336 1.00 61.01  ? 823  PHE A N   1 
ATOM   1940 C CA  . PHE A 1 812  ? 183.489 208.434 195.482 1.00 61.01  ? 823  PHE A CA  1 
ATOM   1941 C C   . PHE A 1 812  ? 183.535 209.317 196.720 1.00 61.01  ? 823  PHE A C   1 
ATOM   1942 O O   . PHE A 1 812  ? 184.390 210.196 196.855 1.00 61.01  ? 823  PHE A O   1 
ATOM   1943 C CB  . PHE A 1 812  ? 184.268 207.130 195.724 1.00 61.01  ? 823  PHE A CB  1 
ATOM   1944 C CG  . PHE A 1 812  ? 185.539 207.315 196.507 1.00 61.01  ? 823  PHE A CG  1 
ATOM   1945 C CD1 . PHE A 1 812  ? 186.708 207.695 195.871 1.00 61.01  ? 823  PHE A CD1 1 
ATOM   1946 C CD2 . PHE A 1 812  ? 185.570 207.090 197.875 1.00 61.01  ? 823  PHE A CD2 1 
ATOM   1947 C CE1 . PHE A 1 812  ? 187.880 207.862 196.583 1.00 61.01  ? 823  PHE A CE1 1 
ATOM   1948 C CE2 . PHE A 1 812  ? 186.739 207.257 198.592 1.00 61.01  ? 823  PHE A CE2 1 
ATOM   1949 C CZ  . PHE A 1 812  ? 187.895 207.643 197.945 1.00 61.01  ? 823  PHE A CZ  1 
ATOM   1950 N N   . PHE A 1 813  ? 182.593 209.067 197.627 1.00 63.53  ? 824  PHE A N   1 
ATOM   1951 C CA  . PHE A 1 813  ? 182.535 209.742 198.919 1.00 63.53  ? 824  PHE A CA  1 
ATOM   1952 C C   . PHE A 1 813  ? 182.343 208.685 199.993 1.00 63.53  ? 824  PHE A C   1 
ATOM   1953 O O   . PHE A 1 813  ? 181.334 207.974 199.989 1.00 63.53  ? 824  PHE A O   1 
ATOM   1954 C CB  . PHE A 1 813  ? 181.399 210.768 198.963 1.00 63.53  ? 824  PHE A CB  1 
ATOM   1955 C CG  . PHE A 1 813  ? 181.484 211.718 200.123 1.00 63.53  ? 824  PHE A CG  1 
ATOM   1956 C CD1 . PHE A 1 813  ? 182.563 212.576 200.256 1.00 63.53  ? 824  PHE A CD1 1 
ATOM   1957 C CD2 . PHE A 1 813  ? 180.486 211.750 201.082 1.00 63.53  ? 824  PHE A CD2 1 
ATOM   1958 C CE1 . PHE A 1 813  ? 182.643 213.450 201.324 1.00 63.53  ? 824  PHE A CE1 1 
ATOM   1959 C CE2 . PHE A 1 813  ? 180.561 212.621 202.152 1.00 63.53  ? 824  PHE A CE2 1 
ATOM   1960 C CZ  . PHE A 1 813  ? 181.641 213.473 202.273 1.00 63.53  ? 824  PHE A CZ  1 
ATOM   1961 N N   . ARG A 1 814  ? 183.302 208.584 200.910 1.00 64.27  ? 825  ARG A N   1 
ATOM   1962 C CA  . ARG A 1 814  ? 183.320 207.535 201.918 1.00 64.27  ? 825  ARG A CA  1 
ATOM   1963 C C   . ARG A 1 814  ? 183.298 208.146 203.312 1.00 64.27  ? 825  ARG A C   1 
ATOM   1964 O O   . ARG A 1 814  ? 184.032 209.098 203.595 1.00 64.27  ? 825  ARG A O   1 
ATOM   1965 C CB  . ARG A 1 814  ? 184.557 206.645 201.753 1.00 64.27  ? 825  ARG A CB  1 
ATOM   1966 C CG  . ARG A 1 814  ? 184.808 205.698 202.911 1.00 64.27  ? 825  ARG A CG  1 
ATOM   1967 C CD  . ARG A 1 814  ? 184.174 204.342 202.664 1.00 64.27  ? 825  ARG A CD  1 
ATOM   1968 N NE  . ARG A 1 814  ? 184.919 203.565 201.682 1.00 64.27  ? 825  ARG A NE  1 
ATOM   1969 C CZ  . ARG A 1 814  ? 185.968 202.806 201.968 1.00 64.27  ? 825  ARG A CZ  1 
ATOM   1970 N NH1 . ARG A 1 814  ? 186.426 202.699 203.204 1.00 64.27  ? 825  ARG A NH1 1 
ATOM   1971 N NH2 . ARG A 1 814  ? 186.572 202.138 200.989 1.00 64.27  ? 825  ARG A NH2 1 
ATOM   1972 N N   . SER A 1 815  ? 182.450 207.594 204.179 1.00 64.84  ? 826  SER A N   1 
ATOM   1973 C CA  . SER A 1 815  ? 182.354 208.032 205.565 1.00 64.84  ? 826  SER A CA  1 
ATOM   1974 C C   . SER A 1 815  ? 182.311 206.812 206.471 1.00 64.84  ? 826  SER A C   1 
ATOM   1975 O O   . SER A 1 815  ? 181.450 205.944 206.304 1.00 64.84  ? 826  SER A O   1 
ATOM   1976 C CB  . SER A 1 815  ? 181.112 208.903 205.788 1.00 64.84  ? 826  SER A CB  1 
ATOM   1977 O OG  . SER A 1 815  ? 181.220 209.646 206.989 1.00 64.84  ? 826  SER A OG  1 
ATOM   1978 N N   . ASP A 1 816  ? 183.236 206.751 207.427 1.00 69.17  ? 827  ASP A N   1 
ATOM   1979 C CA  . ASP A 1 816  ? 183.345 205.632 208.351 1.00 69.17  ? 827  ASP A CA  1 
ATOM   1980 C C   . ASP A 1 816  ? 182.922 206.048 209.754 1.00 69.17  ? 827  ASP A C   1 
ATOM   1981 O O   . ASP A 1 816  ? 182.897 207.235 210.090 1.00 69.17  ? 827  ASP A O   1 
ATOM   1982 C CB  . ASP A 1 816  ? 184.774 205.079 208.401 1.00 69.17  ? 827  ASP A CB  1 
ATOM   1983 C CG  . ASP A 1 816  ? 185.353 204.817 207.027 1.00 69.17  ? 827  ASP A CG  1 
ATOM   1984 O OD1 . ASP A 1 816  ? 184.698 205.162 206.024 1.00 69.17  ? 827  ASP A OD1 1 
ATOM   1985 O OD2 . ASP A 1 816  ? 186.467 204.258 206.951 1.00 69.17  ? 827  ASP A OD2 1 
ATOM   1986 N N   . PHE A 1 817  ? 182.586 205.049 210.568 1.00 70.77  ? 828  PHE A N   1 
ATOM   1987 C CA  . PHE A 1 817  ? 182.270 205.238 211.981 1.00 70.77  ? 828  PHE A CA  1 
ATOM   1988 C C   . PHE A 1 817  ? 182.880 204.075 212.751 1.00 70.77  ? 828  PHE A C   1 
ATOM   1989 O O   . PHE A 1 817  ? 182.393 202.943 212.657 1.00 70.77  ? 828  PHE A O   1 
ATOM   1990 C CB  . PHE A 1 817  ? 180.760 205.318 212.209 1.00 70.77  ? 828  PHE A CB  1 
ATOM   1991 C CG  . PHE A 1 817  ? 180.364 205.327 213.658 1.00 70.77  ? 828  PHE A CG  1 
ATOM   1992 C CD1 . PHE A 1 817  ? 180.457 206.487 214.408 1.00 70.77  ? 828  PHE A CD1 1 
ATOM   1993 C CD2 . PHE A 1 817  ? 179.893 204.176 214.269 1.00 70.77  ? 828  PHE A CD2 1 
ATOM   1994 C CE1 . PHE A 1 817  ? 180.093 206.499 215.742 1.00 70.77  ? 828  PHE A CE1 1 
ATOM   1995 C CE2 . PHE A 1 817  ? 179.528 204.181 215.602 1.00 70.77  ? 828  PHE A CE2 1 
ATOM   1996 C CZ  . PHE A 1 817  ? 179.627 205.345 216.339 1.00 70.77  ? 828  PHE A CZ  1 
ATOM   1997 N N   . VAL A 1 818  ? 183.936 204.350 213.510 1.00 70.12  ? 829  VAL A N   1 
ATOM   1998 C CA  . VAL A 1 818  ? 184.682 203.316 214.218 1.00 70.12  ? 829  VAL A CA  1 
ATOM   1999 C C   . VAL A 1 818  ? 184.224 203.264 215.667 1.00 70.12  ? 829  VAL A C   1 
ATOM   2000 O O   . VAL A 1 818  ? 183.652 204.221 216.201 1.00 70.12  ? 829  VAL A O   1 
ATOM   2001 C CB  . VAL A 1 818  ? 186.203 203.561 214.133 1.00 70.12  ? 829  VAL A CB  1 
ATOM   2002 C CG1 . VAL A 1 818  ? 186.725 203.200 212.753 1.00 70.12  ? 829  VAL A CG1 1 
ATOM   2003 C CG2 . VAL A 1 818  ? 186.523 205.004 214.473 1.00 70.12  ? 829  VAL A CG2 1 
ATOM   2004 N N   . ASN A 1 819  ? 184.482 202.126 216.310 1.00 70.99  ? 830  ASN A N   1 
ATOM   2005 C CA  . ASN A 1 819  ? 184.180 201.928 217.728 1.00 70.99  ? 830  ASN A CA  1 
ATOM   2006 C C   . ASN A 1 819  ? 185.247 200.988 218.280 1.00 70.99  ? 830  ASN A C   1 
ATOM   2007 O O   . ASN A 1 819  ? 185.125 199.766 218.162 1.00 70.99  ? 830  ASN A O   1 
ATOM   2008 C CB  . ASN A 1 819  ? 182.777 201.367 217.927 1.00 70.99  ? 830  ASN A CB  1 
ATOM   2009 C CG  . ASN A 1 819  ? 182.524 200.914 219.353 1.00 70.99  ? 830  ASN A CG  1 
ATOM   2010 O OD1 . ASN A 1 819  ? 182.111 201.703 220.202 1.00 70.99  ? 830  ASN A OD1 1 
ATOM   2011 N ND2 . ASN A 1 819  ? 182.765 199.636 219.620 1.00 70.99  ? 830  ASN A ND2 1 
ATOM   2012 N N   . MET A 1 820  ? 186.288 201.560 218.880 1.00 67.65  ? 831  MET A N   1 
ATOM   2013 C CA  . MET A 1 820  ? 187.445 200.804 219.348 1.00 67.65  ? 831  MET A CA  1 
ATOM   2014 C C   . MET A 1 820  ? 187.255 200.458 220.820 1.00 67.65  ? 831  MET A C   1 
ATOM   2015 O O   . MET A 1 820  ? 187.120 201.350 221.664 1.00 67.65  ? 831  MET A O   1 
ATOM   2016 C CB  . MET A 1 820  ? 188.731 201.599 219.138 1.00 67.65  ? 831  MET A CB  1 
ATOM   2017 C CG  . MET A 1 820  ? 189.956 200.741 218.867 1.00 67.65  ? 831  MET A CG  1 
ATOM   2018 S SD  . MET A 1 820  ? 190.140 200.303 217.130 1.00 67.65  ? 831  MET A SD  1 
ATOM   2019 C CE  . MET A 1 820  ? 191.072 201.707 216.529 1.00 67.65  ? 831  MET A CE  1 
ATOM   2020 N N   . ASN A 1 821  ? 187.247 199.163 221.125 1.00 69.49  ? 832  ASN A N   1 
ATOM   2021 C CA  . ASN A 1 821  ? 187.191 198.671 222.494 1.00 69.49  ? 832  ASN A CA  1 
ATOM   2022 C C   . ASN A 1 821  ? 188.365 197.730 222.722 1.00 69.49  ? 832  ASN A C   1 
ATOM   2023 O O   . ASN A 1 821  ? 188.522 196.741 221.998 1.00 69.49  ? 832  ASN A O   1 
ATOM   2024 C CB  . ASN A 1 821  ? 185.867 197.954 222.774 1.00 69.49  ? 832  ASN A CB  1 
ATOM   2025 C CG  . ASN A 1 821  ? 185.588 197.802 224.256 1.00 69.49  ? 832  ASN A CG  1 
ATOM   2026 O OD1 . ASN A 1 821  ? 186.426 197.309 225.012 1.00 69.49  ? 832  ASN A OD1 1 
ATOM   2027 N ND2 . ASN A 1 821  ? 184.405 198.228 224.681 1.00 69.49  ? 832  ASN A ND2 1 
ATOM   2028 N N   . VAL A 1 822  ? 189.185 198.039 223.727 1.00 67.59  ? 833  VAL A N   1 
ATOM   2029 C CA  . VAL A 1 822  ? 190.388 197.276 224.021 1.00 67.59  ? 833  VAL A CA  1 
ATOM   2030 C C   . VAL A 1 822  ? 190.329 196.612 225.391 1.00 67.59  ? 833  VAL A C   1 
ATOM   2031 O O   . VAL A 1 822  ? 191.342 196.103 225.873 1.00 67.59  ? 833  VAL A O   1 
ATOM   2032 C CB  . VAL A 1 822  ? 191.649 198.154 223.892 1.00 67.59  ? 833  VAL A CB  1 
ATOM   2033 C CG1 . VAL A 1 822  ? 191.683 198.830 222.533 1.00 67.59  ? 833  VAL A CG1 1 
ATOM   2034 C CG2 . VAL A 1 822  ? 191.682 199.192 224.996 1.00 67.59  ? 833  VAL A CG2 1 
ATOM   2035 N N   . GLY A 1 823  ? 189.162 196.598 226.027 1.00 70.33  ? 834  GLY A N   1 
ATOM   2036 C CA  . GLY A 1 823  ? 189.028 195.948 227.314 1.00 70.33  ? 834  GLY A CA  1 
ATOM   2037 C C   . GLY A 1 823  ? 189.388 196.862 228.472 1.00 70.33  ? 834  GLY A C   1 
ATOM   2038 O O   . GLY A 1 823  ? 189.438 198.090 228.354 1.00 70.33  ? 834  GLY A O   1 
ATOM   2039 N N   . SER A 1 824  ? 189.643 196.234 229.618 1.00 76.69  ? 835  SER A N   1 
ATOM   2040 C CA  . SER A 1 824  ? 189.957 196.944 230.847 1.00 76.69  ? 835  SER A CA  1 
ATOM   2041 C C   . SER A 1 824  ? 191.178 196.318 231.506 1.00 76.69  ? 835  SER A C   1 
ATOM   2042 O O   . SER A 1 824  ? 191.484 195.139 231.307 1.00 76.69  ? 835  SER A O   1 
ATOM   2043 C CB  . SER A 1 824  ? 188.770 196.933 231.820 1.00 76.69  ? 835  SER A CB  1 
ATOM   2044 O OG  . SER A 1 824  ? 187.686 197.689 231.310 1.00 76.69  ? 835  SER A OG  1 
ATOM   2045 N N   . PHE A 1 825  ? 191.876 197.129 232.296 1.00 78.08  ? 836  PHE A N   1 
ATOM   2046 C CA  . PHE A 1 825  ? 193.067 196.659 232.991 1.00 78.08  ? 836  PHE A CA  1 
ATOM   2047 C C   . PHE A 1 825  ? 192.702 195.624 234.047 1.00 78.08  ? 836  PHE A C   1 
ATOM   2048 O O   . PHE A 1 825  ? 191.708 195.764 234.764 1.00 78.08  ? 836  PHE A O   1 
ATOM   2049 C CB  . PHE A 1 825  ? 193.800 197.832 233.641 1.00 78.08  ? 836  PHE A CB  1 
ATOM   2050 C CG  . PHE A 1 825  ? 194.481 198.741 232.659 1.00 78.08  ? 836  PHE A CG  1 
ATOM   2051 C CD1 . PHE A 1 825  ? 195.765 198.470 232.220 1.00 78.08  ? 836  PHE A CD1 1 
ATOM   2052 C CD2 . PHE A 1 825  ? 193.836 199.867 232.175 1.00 78.08  ? 836  PHE A CD2 1 
ATOM   2053 C CE1 . PHE A 1 825  ? 196.395 199.304 231.317 1.00 78.08  ? 836  PHE A CE1 1 
ATOM   2054 C CE2 . PHE A 1 825  ? 194.460 200.705 231.272 1.00 78.08  ? 836  PHE A CE2 1 
ATOM   2055 C CZ  . PHE A 1 825  ? 195.741 200.423 230.842 1.00 78.08  ? 836  PHE A CZ  1 
ATOM   2056 N N   . SER A 1 826  ? 193.520 194.574 234.139 1.00 87.19  ? 837  SER A N   1 
ATOM   2057 C CA  . SER A 1 826  ? 193.320 193.510 235.122 1.00 87.19  ? 837  SER A CA  1 
ATOM   2058 C C   . SER A 1 826  ? 194.025 193.907 236.416 1.00 87.19  ? 837  SER A C   1 
ATOM   2059 O O   . SER A 1 826  ? 195.097 193.406 236.765 1.00 87.19  ? 837  SER A O   1 
ATOM   2060 C CB  . SER A 1 826  ? 193.832 192.179 234.586 1.00 87.19  ? 837  SER A CB  1 
ATOM   2061 O OG  . SER A 1 826  ? 195.249 192.142 234.588 1.00 87.19  ? 837  SER A OG  1 
ATOM   2062 N N   . THR A 1 827  ? 193.402 194.834 237.141 1.00 89.75  ? 838  THR A N   1 
ATOM   2063 C CA  . THR A 1 827  ? 193.979 195.330 238.384 1.00 89.75  ? 838  THR A CA  1 
ATOM   2064 C C   . THR A 1 827  ? 193.870 194.271 239.479 1.00 89.75  ? 838  THR A C   1 
ATOM   2065 O O   . THR A 1 827  ? 192.803 193.686 239.692 1.00 89.75  ? 838  THR A O   1 
ATOM   2066 C CB  . THR A 1 827  ? 193.296 196.633 238.803 1.00 89.75  ? 838  THR A CB  1 
ATOM   2067 O OG1 . THR A 1 827  ? 193.897 197.128 240.006 1.00 89.75  ? 838  THR A OG1 1 
ATOM   2068 C CG2 . THR A 1 827  ? 191.794 196.446 239.008 1.00 89.75  ? 838  THR A CG2 1 
ATOM   2069 N N   . ASN A 1 828  ? 194.986 194.012 240.158 1.00 97.20  ? 839  ASN A N   1 
ATOM   2070 C CA  . ASN A 1 828  ? 195.048 193.031 241.233 1.00 97.20  ? 839  ASN A CA  1 
ATOM   2071 C C   . ASN A 1 828  ? 195.694 193.554 242.507 1.00 97.20  ? 839  ASN A C   1 
ATOM   2072 O O   . ASN A 1 828  ? 195.391 193.042 243.586 1.00 97.20  ? 839  ASN A O   1 
ATOM   2073 C CB  . ASN A 1 828  ? 195.820 191.780 240.778 1.00 97.20  ? 839  ASN A CB  1 
ATOM   2074 C CG  . ASN A 1 828  ? 195.138 191.051 239.634 1.00 97.20  ? 839  ASN A CG  1 
ATOM   2075 O OD1 . ASN A 1 828  ? 193.939 191.207 239.406 1.00 97.20  ? 839  ASN A OD1 1 
ATOM   2076 N ND2 . ASN A 1 828  ? 195.905 190.246 238.908 1.00 97.20  ? 839  ASN A ND2 1 
ATOM   2077 N N   . ALA A 1 829  ? 196.569 194.556 242.414 1.00 94.77  ? 840  ALA A N   1 
ATOM   2078 C CA  . ALA A 1 829  ? 197.306 195.058 243.574 1.00 94.77  ? 840  ALA A CA  1 
ATOM   2079 C C   . ALA A 1 829  ? 196.496 196.125 244.315 1.00 94.77  ? 840  ALA A C   1 
ATOM   2080 O O   . ALA A 1 829  ? 196.896 197.283 244.441 1.00 94.77  ? 840  ALA A O   1 
ATOM   2081 C CB  . ALA A 1 829  ? 198.664 195.593 243.140 1.00 94.77  ? 840  ALA A CB  1 
ATOM   2082 N N   . ASP A 1 830  ? 195.332 195.702 244.812 1.00 93.48  ? 841  ASP A N   1 
ATOM   2083 C CA  . ASP A 1 830  ? 194.439 196.550 245.602 1.00 93.48  ? 841  ASP A CA  1 
ATOM   2084 C C   . ASP A 1 830  ? 194.058 197.815 244.828 1.00 93.48  ? 841  ASP A C   1 
ATOM   2085 O O   . ASP A 1 830  ? 194.371 198.942 245.219 1.00 93.48  ? 841  ASP A O   1 
ATOM   2086 C CB  . ASP A 1 830  ? 195.070 196.892 246.958 1.00 93.48  ? 841  ASP A CB  1 
ATOM   2087 C CG  . ASP A 1 830  ? 194.107 197.607 247.887 1.00 93.48  ? 841  ASP A CG  1 
ATOM   2088 O OD1 . ASP A 1 830  ? 193.148 196.964 248.362 1.00 93.48  ? 841  ASP A OD1 1 
ATOM   2089 O OD2 . ASP A 1 830  ? 194.311 198.813 248.142 1.00 93.48  ? 841  ASP A OD2 1 
ATOM   2090 N N   . GLY A 1 831  ? 193.377 197.604 243.704 1.00 91.04  ? 842  GLY A N   1 
ATOM   2091 C CA  . GLY A 1 831  ? 192.954 198.716 242.878 1.00 91.04  ? 842  GLY A CA  1 
ATOM   2092 C C   . GLY A 1 831  ? 194.054 199.363 242.072 1.00 91.04  ? 842  GLY A C   1 
ATOM   2093 O O   . GLY A 1 831  ? 193.892 200.500 241.621 1.00 91.04  ? 842  GLY A O   1 
ATOM   2094 N N   . LYS A 1 832  ? 195.165 198.640 241.911 1.00 86.09  ? 843  LYS A N   1 
ATOM   2095 C CA  . LYS A 1 832  ? 196.318 199.184 241.153 1.00 86.09  ? 843  LYS A CA  1 
ATOM   2096 C C   . LYS A 1 832  ? 196.821 198.129 240.164 1.00 86.09  ? 843  LYS A C   1 
ATOM   2097 O O   . LYS A 1 832  ? 196.690 196.925 240.469 1.00 86.09  ? 843  LYS A O   1 
ATOM   2098 C CB  . LYS A 1 832  ? 197.445 199.594 242.106 1.00 86.09  ? 843  LYS A CB  1 
ATOM   2099 C CG  . LYS A 1 832  ? 197.145 200.804 242.976 1.00 86.09  ? 843  LYS A CG  1 
ATOM   2100 C CD  . LYS A 1 832  ? 196.802 202.038 242.152 1.00 86.09  ? 843  LYS A CD  1 
ATOM   2101 C CE  . LYS A 1 832  ? 196.686 203.268 242.992 1.00 86.09  ? 843  LYS A CE  1 
ATOM   2102 N NZ  . LYS A 1 832  ? 197.945 203.563 243.680 1.00 86.09  ? 843  LYS A NZ  1 
ATOM   2103 N N   . TRP A 1 833  ? 197.359 198.569 239.028 1.00 81.54  ? 844  TRP A N   1 
ATOM   2104 C CA  . TRP A 1 833  ? 197.908 197.673 238.021 1.00 81.54  ? 844  TRP A CA  1 
ATOM   2105 C C   . TRP A 1 833  ? 199.275 198.175 237.585 1.00 81.54  ? 844  TRP A C   1 
ATOM   2106 O O   . TRP A 1 833  ? 199.490 199.383 237.452 1.00 81.54  ? 844  TRP A O   1 
ATOM   2107 C CB  . TRP A 1 833  ? 196.977 197.554 236.807 1.00 81.54  ? 844  TRP A CB  1 
ATOM   2108 C CG  . TRP A 1 833  ? 196.702 198.857 236.118 1.00 81.54  ? 844  TRP A CG  1 
ATOM   2109 C CD1 . TRP A 1 833  ? 197.450 199.438 235.136 1.00 81.54  ? 844  TRP A CD1 1 
ATOM   2110 C CD2 . TRP A 1 833  ? 195.597 199.737 236.355 1.00 81.54  ? 844  TRP A CD2 1 
ATOM   2111 N NE1 . TRP A 1 833  ? 196.881 200.627 234.748 1.00 81.54  ? 844  TRP A NE1 1 
ATOM   2112 C CE2 . TRP A 1 833  ? 195.742 200.833 235.482 1.00 81.54  ? 844  TRP A CE2 1 
ATOM   2113 C CE3 . TRP A 1 833  ? 194.500 199.706 237.221 1.00 81.54  ? 844  TRP A CE3 1 
ATOM   2114 C CZ2 . TRP A 1 833  ? 194.832 201.887 235.450 1.00 81.54  ? 844  TRP A CZ2 1 
ATOM   2115 C CZ3 . TRP A 1 833  ? 193.598 200.753 237.187 1.00 81.54  ? 844  TRP A CZ3 1 
ATOM   2116 C CH2 . TRP A 1 833  ? 193.769 201.829 236.307 1.00 81.54  ? 844  TRP A CH2 1 
ATOM   2117 N N   . ASP A 1 834  ? 200.209 197.234 237.389 1.00 81.71  ? 845  ASP A N   1 
ATOM   2118 C CA  . ASP A 1 834  ? 201.597 197.584 236.969 1.00 81.71  ? 845  ASP A CA  1 
ATOM   2119 C C   . ASP A 1 834  ? 201.946 196.820 235.688 1.00 81.71  ? 845  ASP A C   1 
ATOM   2120 O O   . ASP A 1 834  ? 202.589 195.754 235.796 1.00 81.71  ? 845  ASP A O   1 
ATOM   2121 C CB  . ASP A 1 834  ? 202.595 197.339 238.089 1.00 81.71  ? 845  ASP A CB  1 
ATOM   2122 C CG  . ASP A 1 834  ? 202.515 198.309 239.259 1.00 81.71  ? 845  ASP A CG  1 
ATOM   2123 O OD1 . ASP A 1 834  ? 201.871 199.365 239.102 1.00 81.71  ? 845  ASP A OD1 1 
ATOM   2124 O OD2 . ASP A 1 834  ? 203.101 198.000 240.318 1.00 81.71  ? 845  ASP A OD2 1 
ATOM   2125 N N   . ASP A 1 835  ? 201.535 197.383 234.548 1.00 76.23  ? 846  ASP A N   1 
ATOM   2126 C CA  . ASP A 1 835  ? 201.776 196.728 233.240 1.00 76.23  ? 846  ASP A CA  1 
ATOM   2127 C C   . ASP A 1 835  ? 202.689 197.608 232.391 1.00 76.23  ? 846  ASP A C   1 
ATOM   2128 O O   . ASP A 1 835  ? 202.876 198.791 232.741 1.00 76.23  ? 846  ASP A O   1 
ATOM   2129 C CB  . ASP A 1 835  ? 200.473 196.482 232.499 1.00 76.23  ? 846  ASP A CB  1 
ATOM   2130 C CG  . ASP A 1 835  ? 199.580 195.396 233.078 1.00 76.23  ? 846  ASP A CG  1 
ATOM   2131 O OD1 . ASP A 1 835  ? 200.079 194.609 233.908 1.00 76.23  ? 846  ASP A OD1 1 
ATOM   2132 O OD2 . ASP A 1 835  ? 198.395 195.345 232.690 1.00 76.23  ? 846  ASP A OD2 1 
ATOM   2133 N N   . ASN A 1 836  ? 203.216 197.050 231.308 1.00 64.12  ? 847  ASN A N   1 
ATOM   2134 C CA  . ASN A 1 836  ? 204.097 197.776 230.393 1.00 64.12  ? 847  ASN A CA  1 
ATOM   2135 C C   . ASN A 1 836  ? 203.249 198.664 229.480 1.00 64.12  ? 847  ASN A C   1 
ATOM   2136 O O   . ASN A 1 836  ? 203.153 198.472 228.266 1.00 64.12  ? 847  ASN A O   1 
ATOM   2137 C CB  . ASN A 1 836  ? 204.956 196.804 229.597 1.00 64.12  ? 847  ASN A CB  1 
ATOM   2138 C CG  . ASN A 1 836  ? 205.985 197.507 228.735 1.00 64.12  ? 847  ASN A CG  1 
ATOM   2139 O OD1 . ASN A 1 836  ? 207.086 197.814 229.189 1.00 64.12  ? 847  ASN A OD1 1 
ATOM   2140 N ND2 . ASN A 1 836  ? 205.630 197.764 227.481 1.00 64.12  ? 847  ASN A ND2 1 
ATOM   2141 N N   . TRP A 1 837  ? 202.619 199.659 230.100 1.00 62.40  ? 848  TRP A N   1 
ATOM   2142 C CA  . TRP A 1 837  ? 201.768 200.601 229.386 1.00 62.40  ? 848  TRP A CA  1 
ATOM   2143 C C   . TRP A 1 837  ? 201.881 201.959 230.059 1.00 62.40  ? 848  TRP A C   1 
ATOM   2144 O O   . TRP A 1 837  ? 201.745 202.056 231.282 1.00 62.40  ? 848  TRP A O   1 
ATOM   2145 C CB  . TRP A 1 837  ? 200.310 200.127 229.366 1.00 62.40  ? 848  TRP A CB  1 
ATOM   2146 C CG  . TRP A 1 837  ? 199.349 201.134 228.809 1.00 62.40  ? 848  TRP A CG  1 
ATOM   2147 C CD1 . TRP A 1 837  ? 198.941 201.245 227.513 1.00 62.40  ? 848  TRP A CD1 1 
ATOM   2148 C CD2 . TRP A 1 837  ? 198.664 202.163 229.534 1.00 62.40  ? 848  TRP A CD2 1 
ATOM   2149 N NE1 . TRP A 1 837  ? 198.051 202.283 227.383 1.00 62.40  ? 848  TRP A NE1 1 
ATOM   2150 C CE2 . TRP A 1 837  ? 197.864 202.862 228.610 1.00 62.40  ? 848  TRP A CE2 1 
ATOM   2151 C CE3 . TRP A 1 837  ? 198.652 202.562 230.874 1.00 62.40  ? 848  TRP A CE3 1 
ATOM   2152 C CZ2 . TRP A 1 837  ? 197.061 203.938 228.983 1.00 62.40  ? 848  TRP A CZ2 1 
ATOM   2153 C CZ3 . TRP A 1 837  ? 197.855 203.629 231.241 1.00 62.40  ? 848  TRP A CZ3 1 
ATOM   2154 C CH2 . TRP A 1 837  ? 197.070 204.305 230.300 1.00 62.40  ? 848  TRP A CH2 1 
ATOM   2155 N N   . GLY A 1 838  ? 202.119 202.996 229.262 1.00 64.03  ? 849  GLY A N   1 
ATOM   2156 C CA  . GLY A 1 838  ? 202.294 204.324 229.825 1.00 64.03  ? 849  GLY A CA  1 
ATOM   2157 C C   . GLY A 1 838  ? 203.485 204.364 230.760 1.00 64.03  ? 849  GLY A C   1 
ATOM   2158 O O   . GLY A 1 838  ? 204.593 203.940 230.413 1.00 64.03  ? 849  GLY A O   1 
ATOM   2159 N N   . THR A 1 839  ? 203.261 204.879 231.966 1.00 66.90  ? 850  THR A N   1 
ATOM   2160 C CA  . THR A 1 839  ? 204.280 204.954 233.005 1.00 66.90  ? 850  THR A CA  1 
ATOM   2161 C C   . THR A 1 839  ? 203.824 204.224 234.262 1.00 66.90  ? 850  THR A C   1 
ATOM   2162 O O   . THR A 1 839  ? 204.134 204.627 235.385 1.00 66.90  ? 850  THR A O   1 
ATOM   2163 C CB  . THR A 1 839  ? 204.626 206.406 233.328 1.00 66.90  ? 850  THR A CB  1 
ATOM   2164 O OG1 . THR A 1 839  ? 203.440 207.105 233.722 1.00 66.90  ? 850  THR A OG1 1 
ATOM   2165 C CG2 . THR A 1 839  ? 205.232 207.092 232.114 1.00 66.90  ? 850  THR A CG2 1 
ATOM   2166 N N   . CYS A 1 840  ? 203.073 203.135 234.083 1.00 75.06  ? 851  CYS A N   1 
ATOM   2167 C CA  . CYS A 1 840  ? 202.549 202.396 235.225 1.00 75.06  ? 851  CYS A CA  1 
ATOM   2168 C C   . CYS A 1 840  ? 203.614 201.560 235.922 1.00 75.06  ? 851  CYS A C   1 
ATOM   2169 O O   . CYS A 1 840  ? 203.435 201.205 237.091 1.00 75.06  ? 851  CYS A O   1 
ATOM   2170 C CB  . CYS A 1 840  ? 201.389 201.503 234.785 1.00 75.06  ? 851  CYS A CB  1 
ATOM   2171 S SG  . CYS A 1 840  ? 199.980 202.409 234.109 1.00 75.06  ? 851  CYS A SG  1 
ATOM   2172 N N   . THR A 1 841  ? 204.712 201.235 235.238 1.00 69.48  ? 852  THR A N   1 
ATOM   2173 C CA  . THR A 1 841  ? 205.779 200.462 235.859 1.00 69.48  ? 852  THR A CA  1 
ATOM   2174 C C   . THR A 1 841  ? 206.667 201.301 236.768 1.00 69.48  ? 852  THR A C   1 
ATOM   2175 O O   . THR A 1 841  ? 207.449 200.731 237.537 1.00 69.48  ? 852  THR A O   1 
ATOM   2176 C CB  . THR A 1 841  ? 206.638 199.783 234.791 1.00 69.48  ? 852  THR A CB  1 
ATOM   2177 O OG1 . THR A 1 841  ? 207.727 199.095 235.419 1.00 69.48  ? 852  THR A OG1 1 
ATOM   2178 C CG2 . THR A 1 841  ? 207.189 200.810 233.821 1.00 69.48  ? 852  THR A CG2 1 
ATOM   2179 N N   . LEU A 1 842  ? 206.572 202.628 236.699 1.00 69.48  ? 853  LEU A N   1 
ATOM   2180 C CA  . LEU A 1 842  ? 207.274 203.498 237.635 1.00 69.48  ? 853  LEU A CA  1 
ATOM   2181 C C   . LEU A 1 842  ? 206.426 203.810 238.861 1.00 69.48  ? 853  LEU A C   1 
ATOM   2182 O O   . LEU A 1 842  ? 206.953 203.905 239.975 1.00 69.48  ? 853  LEU A O   1 
ATOM   2183 C CB  . LEU A 1 842  ? 207.679 204.804 236.947 1.00 69.48  ? 853  LEU A CB  1 
ATOM   2184 C CG  . LEU A 1 842  ? 208.546 204.734 235.691 1.00 69.48  ? 853  LEU A CG  1 
ATOM   2185 C CD1 . LEU A 1 842  ? 208.767 206.130 235.136 1.00 69.48  ? 853  LEU A CD1 1 
ATOM   2186 C CD2 . LEU A 1 842  ? 209.873 204.063 235.993 1.00 69.48  ? 853  LEU A CD2 1 
ATOM   2187 N N   . GLN A 1 843  ? 205.119 203.971 238.671 1.00 74.67  ? 854  GLN A N   1 
ATOM   2188 C CA  . GLN A 1 843  ? 204.191 204.225 239.761 1.00 74.67  ? 854  GLN A CA  1 
ATOM   2189 C C   . GLN A 1 843  ? 202.844 203.630 239.380 1.00 74.67  ? 854  GLN A C   1 
ATOM   2190 O O   . GLN A 1 843  ? 202.452 203.673 238.212 1.00 74.67  ? 854  GLN A O   1 
ATOM   2191 C CB  . GLN A 1 843  ? 204.062 205.726 240.052 1.00 74.67  ? 854  GLN A CB  1 
ATOM   2192 C CG  . GLN A 1 843  ? 203.037 206.069 241.122 1.00 74.67  ? 854  GLN A CG  1 
ATOM   2193 C CD  . GLN A 1 843  ? 203.297 207.413 241.772 1.00 74.67  ? 854  GLN A CD  1 
ATOM   2194 O OE1 . GLN A 1 843  ? 204.445 207.822 241.942 1.00 74.67  ? 854  GLN A OE1 1 
ATOM   2195 N NE2 . GLN A 1 843  ? 202.228 208.107 242.142 1.00 74.67  ? 854  GLN A NE2 1 
ATOM   2196 N N   . ASP A 1 844  ? 202.148 203.075 240.370 1.00 80.31  ? 855  ASP A N   1 
ATOM   2197 C CA  . ASP A 1 844  ? 200.891 202.386 240.111 1.00 80.31  ? 855  ASP A CA  1 
ATOM   2198 C C   . ASP A 1 844  ? 199.860 203.336 239.513 1.00 80.31  ? 855  ASP A C   1 
ATOM   2199 O O   . ASP A 1 844  ? 199.756 204.500 239.908 1.00 80.31  ? 855  ASP A O   1 
ATOM   2200 C CB  . ASP A 1 844  ? 200.355 201.772 241.404 1.00 80.31  ? 855  ASP A CB  1 
ATOM   2201 C CG  . ASP A 1 844  ? 201.426 201.035 242.185 1.00 80.31  ? 855  ASP A CG  1 
ATOM   2202 O OD1 . ASP A 1 844  ? 202.547 200.879 241.659 1.00 80.31  ? 855  ASP A OD1 1 
ATOM   2203 O OD2 . ASP A 1 844  ? 201.145 200.614 243.327 1.00 80.31  ? 855  ASP A OD2 1 
ATOM   2204 N N   . CYS A 1 845  ? 199.094 202.828 238.553 1.00 83.69  ? 856  CYS A N   1 
ATOM   2205 C CA  . CYS A 1 845  ? 198.101 203.612 237.836 1.00 83.69  ? 856  CYS A CA  1 
ATOM   2206 C C   . CYS A 1 845  ? 196.707 203.335 238.386 1.00 83.69  ? 856  CYS A C   1 
ATOM   2207 O O   . CYS A 1 845  ? 196.409 202.230 238.846 1.00 83.69  ? 856  CYS A O   1 
ATOM   2208 C CB  . CYS A 1 845  ? 198.136 203.295 236.340 1.00 83.69  ? 856  CYS A CB  1 
ATOM   2209 S SG  . CYS A 1 845  ? 199.623 203.860 235.484 1.00 83.69  ? 856  CYS A SG  1 
ATOM   2210 N N   . SER A 1 846  ? 195.854 204.355 238.331 1.00 85.50  ? 857  SER A N   1 
ATOM   2211 C CA  . SER A 1 846  ? 194.489 204.229 238.821 1.00 85.50  ? 857  SER A CA  1 
ATOM   2212 C C   . SER A 1 846  ? 193.627 205.311 238.186 1.00 85.50  ? 857  SER A C   1 
ATOM   2213 O O   . SER A 1 846  ? 194.102 206.420 237.931 1.00 85.50  ? 857  SER A O   1 
ATOM   2214 C CB  . SER A 1 846  ? 194.435 204.334 240.350 1.00 85.50  ? 857  SER A CB  1 
ATOM   2215 O OG  . SER A 1 846  ? 194.892 205.601 240.788 1.00 85.50  ? 857  SER A OG  1 
ATOM   2216 N N   . GLY A 1 847  ? 192.363 204.977 237.938 1.00 85.06  ? 858  GLY A N   1 
ATOM   2217 C CA  . GLY A 1 847  ? 191.394 205.940 237.450 1.00 85.06  ? 858  GLY A CA  1 
ATOM   2218 C C   . GLY A 1 847  ? 190.810 205.630 236.086 1.00 85.06  ? 858  GLY A C   1 
ATOM   2219 O O   . GLY A 1 847  ? 189.603 205.788 235.879 1.00 85.06  ? 858  GLY A O   1 
ATOM   2220 N N   . ASN A 1 848  ? 191.644 205.192 235.142 1.00 84.43  ? 859  ASN A N   1 
ATOM   2221 C CA  . ASN A 1 848  ? 191.171 204.820 233.808 1.00 84.43  ? 859  ASN A CA  1 
ATOM   2222 C C   . ASN A 1 848  ? 191.161 203.297 233.643 1.00 84.43  ? 859  ASN A C   1 
ATOM   2223 O O   . ASN A 1 848  ? 191.895 202.719 232.842 1.00 84.43  ? 859  ASN A O   1 
ATOM   2224 C CB  . ASN A 1 848  ? 192.022 205.487 232.736 1.00 84.43  ? 859  ASN A CB  1 
ATOM   2225 C CG  . ASN A 1 848  ? 193.490 205.521 233.096 1.00 84.43  ? 859  ASN A CG  1 
ATOM   2226 O OD1 . ASN A 1 848  ? 193.880 205.138 234.198 1.00 84.43  ? 859  ASN A OD1 1 
ATOM   2227 N ND2 . ASN A 1 848  ? 194.316 205.973 232.161 1.00 84.43  ? 859  ASN A ND2 1 
ATOM   2228 N N   . ARG A 1 849  ? 190.305 202.646 234.434 1.00 87.06  ? 860  ARG A N   1 
ATOM   2229 C CA  . ARG A 1 849  ? 190.220 201.190 234.382 1.00 87.06  ? 860  ARG A CA  1 
ATOM   2230 C C   . ARG A 1 849  ? 189.713 200.713 233.027 1.00 87.06  ? 860  ARG A C   1 
ATOM   2231 O O   . ARG A 1 849  ? 190.224 199.731 232.476 1.00 87.06  ? 860  ARG A O   1 
ATOM   2232 C CB  . ARG A 1 849  ? 189.322 200.677 235.507 1.00 87.06  ? 860  ARG A CB  1 
ATOM   2233 C CG  . ARG A 1 849  ? 189.200 199.163 235.562 1.00 87.06  ? 860  ARG A CG  1 
ATOM   2234 C CD  . ARG A 1 849  ? 188.598 198.719 236.882 1.00 87.06  ? 860  ARG A CD  1 
ATOM   2235 N NE  . ARG A 1 849  ? 189.374 199.213 238.013 1.00 87.06  ? 860  ARG A NE  1 
ATOM   2236 C CZ  . ARG A 1 849  ? 189.077 198.985 239.284 1.00 87.06  ? 860  ARG A CZ  1 
ATOM   2237 N NH1 . ARG A 1 849  ? 188.021 198.267 239.630 1.00 87.06  ? 860  ARG A NH1 1 
ATOM   2238 N NH2 . ARG A 1 849  ? 189.860 199.490 240.234 1.00 87.06  ? 860  ARG A NH2 1 
ATOM   2239 N N   . SER A 1 850  ? 188.718 201.397 232.471 1.00 80.76  ? 861  SER A N   1 
ATOM   2240 C CA  . SER A 1 850  ? 188.145 201.040 231.181 1.00 80.76  ? 861  SER A CA  1 
ATOM   2241 C C   . SER A 1 850  ? 188.720 201.933 230.089 1.00 80.76  ? 861  SER A C   1 
ATOM   2242 O O   . SER A 1 850  ? 188.812 203.153 230.254 1.00 80.76  ? 861  SER A O   1 
ATOM   2243 C CB  . SER A 1 850  ? 186.621 201.163 231.208 1.00 80.76  ? 861  SER A CB  1 
ATOM   2244 O OG  . SER A 1 850  ? 186.055 200.772 229.969 1.00 80.76  ? 861  SER A OG  1 
ATOM   2245 N N   . GLN A 1 851  ? 189.107 201.316 228.974 1.00 79.53  ? 862  GLN A N   1 
ATOM   2246 C CA  . GLN A 1 851  ? 189.694 202.023 227.836 1.00 79.53  ? 862  GLN A CA  1 
ATOM   2247 C C   . GLN A 1 851  ? 188.890 201.678 226.585 1.00 79.53  ? 862  GLN A C   1 
ATOM   2248 O O   . GLN A 1 851  ? 188.916 200.535 226.119 1.00 79.53  ? 862  GLN A O   1 
ATOM   2249 C CB  . GLN A 1 851  ? 191.166 201.662 227.662 1.00 79.53  ? 862  GLN A CB  1 
ATOM   2250 C CG  . GLN A 1 851  ? 192.033 201.948 228.878 1.00 79.53  ? 862  GLN A CG  1 
ATOM   2251 C CD  . GLN A 1 851  ? 192.434 203.406 228.980 1.00 79.53  ? 862  GLN A CD  1 
ATOM   2252 O OE1 . GLN A 1 851  ? 192.069 204.223 228.134 1.00 79.53  ? 862  GLN A OE1 1 
ATOM   2253 N NE2 . GLN A 1 851  ? 193.192 203.739 230.018 1.00 79.53  ? 862  GLN A NE2 1 
ATOM   2254 N N   . SER A 1 852  ? 188.177 202.666 226.049 1.00 74.95  ? 863  SER A N   1 
ATOM   2255 C CA  . SER A 1 852  ? 187.423 202.493 224.816 1.00 74.95  ? 863  SER A CA  1 
ATOM   2256 C C   . SER A 1 852  ? 187.277 203.847 224.139 1.00 74.95  ? 863  SER A C   1 
ATOM   2257 O O   . SER A 1 852  ? 187.384 204.896 224.779 1.00 74.95  ? 863  SER A O   1 
ATOM   2258 C CB  . SER A 1 852  ? 186.048 201.867 225.076 1.00 74.95  ? 863  SER A CB  1 
ATOM   2259 O OG  . SER A 1 852  ? 185.235 202.729 225.853 1.00 74.95  ? 863  SER A OG  1 
ATOM   2260 N N   . ASP A 1 853  ? 187.028 203.814 222.832 1.00 69.67  ? 864  ASP A N   1 
ATOM   2261 C CA  . ASP A 1 853  ? 186.891 205.045 222.067 1.00 69.67  ? 864  ASP A CA  1 
ATOM   2262 C C   . ASP A 1 853  ? 186.096 204.766 220.800 1.00 69.67  ? 864  ASP A C   1 
ATOM   2263 O O   . ASP A 1 853  ? 185.966 203.620 220.363 1.00 69.67  ? 864  ASP A O   1 
ATOM   2264 C CB  . ASP A 1 853  ? 188.259 205.646 221.723 1.00 69.67  ? 864  ASP A CB  1 
ATOM   2265 C CG  . ASP A 1 853  ? 188.257 207.160 221.771 1.00 69.67  ? 864  ASP A CG  1 
ATOM   2266 O OD1 . ASP A 1 853  ? 187.180 207.748 222.006 1.00 69.67  ? 864  ASP A OD1 1 
ATOM   2267 O OD2 . ASP A 1 853  ? 189.333 207.764 221.575 1.00 69.67  ? 864  ASP A OD2 1 
ATOM   2268 N N   . SER A 1 854  ? 185.567 205.840 220.217 1.00 70.01  ? 865  SER A N   1 
ATOM   2269 C CA  . SER A 1 854  ? 184.816 205.758 218.973 1.00 70.01  ? 865  SER A CA  1 
ATOM   2270 C C   . SER A 1 854  ? 184.933 207.088 218.244 1.00 70.01  ? 865  SER A C   1 
ATOM   2271 O O   . SER A 1 854  ? 185.235 208.123 218.844 1.00 70.01  ? 865  SER A O   1 
ATOM   2272 C CB  . SER A 1 854  ? 183.345 205.407 219.225 1.00 70.01  ? 865  SER A CB  1 
ATOM   2273 O OG  . SER A 1 854  ? 182.727 206.366 220.064 1.00 70.01  ? 865  SER A OG  1 
ATOM   2274 N N   . GLY A 1 855  ? 184.689 207.051 216.939 1.00 68.62  ? 866  GLY A N   1 
ATOM   2275 C CA  . GLY A 1 855  ? 184.793 208.260 216.143 1.00 68.62  ? 866  GLY A CA  1 
ATOM   2276 C C   . GLY A 1 855  ? 184.250 208.042 214.748 1.00 68.62  ? 866  GLY A C   1 
ATOM   2277 O O   . GLY A 1 855  ? 183.817 206.946 214.387 1.00 68.62  ? 866  GLY A O   1 
ATOM   2278 N N   . ALA A 1 856  ? 184.282 209.118 213.963 1.00 63.06  ? 867  ALA A N   1 
ATOM   2279 C CA  . ALA A 1 856  ? 183.803 209.105 212.590 1.00 63.06  ? 867  ALA A CA  1 
ATOM   2280 C C   . ALA A 1 856  ? 184.808 209.806 211.687 1.00 63.06  ? 867  ALA A C   1 
ATOM   2281 O O   . ALA A 1 856  ? 185.483 210.753 212.100 1.00 63.06  ? 867  ALA A O   1 
ATOM   2282 C CB  . ALA A 1 856  ? 182.431 209.780 212.466 1.00 63.06  ? 867  ALA A CB  1 
ATOM   2283 N N   . SER A 1 857  ? 184.894 209.334 210.445 1.00 61.42  ? 868  SER A N   1 
ATOM   2284 C CA  . SER A 1 857  ? 185.820 209.874 209.461 1.00 61.42  ? 868  SER A CA  1 
ATOM   2285 C C   . SER A 1 857  ? 185.095 210.094 208.141 1.00 61.42  ? 868  SER A C   1 
ATOM   2286 O O   . SER A 1 857  ? 184.067 209.472 207.862 1.00 61.42  ? 868  SER A O   1 
ATOM   2287 C CB  . SER A 1 857  ? 187.023 208.944 209.250 1.00 61.42  ? 868  SER A CB  1 
ATOM   2288 O OG  . SER A 1 857  ? 186.658 207.806 208.489 1.00 61.42  ? 868  SER A OG  1 
ATOM   2289 N N   . VAL A 1 858  ? 185.644 210.994 207.329 1.00 59.61  ? 869  VAL A N   1 
ATOM   2290 C CA  . VAL A 1 858  ? 185.084 211.326 206.024 1.00 59.61  ? 869  VAL A CA  1 
ATOM   2291 C C   . VAL A 1 858  ? 186.203 211.306 204.993 1.00 59.61  ? 869  VAL A C   1 
ATOM   2292 O O   . VAL A 1 858  ? 187.302 211.811 205.243 1.00 59.61  ? 869  VAL A O   1 
ATOM   2293 C CB  . VAL A 1 858  ? 184.375 212.696 206.039 1.00 59.61  ? 869  VAL A CB  1 
ATOM   2294 C CG1 . VAL A 1 858  ? 183.002 212.574 206.679 1.00 59.61  ? 869  VAL A CG1 1 
ATOM   2295 C CG2 . VAL A 1 858  ? 185.219 213.724 206.776 1.00 59.61  ? 869  VAL A CG2 1 
ATOM   2296 N N   . ALA A 1 859  ? 185.923 210.716 203.832 1.00 58.76  ? 870  ALA A N   1 
ATOM   2297 C CA  . ALA A 1 859  ? 186.904 210.604 202.763 1.00 58.76  ? 870  ALA A CA  1 
ATOM   2298 C C   . ALA A 1 859  ? 186.258 210.954 201.432 1.00 58.76  ? 870  ALA A C   1 
ATOM   2299 O O   . ALA A 1 859  ? 185.125 210.549 201.158 1.00 58.76  ? 870  ALA A O   1 
ATOM   2300 C CB  . ALA A 1 859  ? 187.501 209.194 202.698 1.00 58.76  ? 870  ALA A CB  1 
ATOM   2301 N N   . VAL A 1 860  ? 186.985 211.708 200.611 1.00 56.82  ? 871  VAL A N   1 
ATOM   2302 C CA  . VAL A 1 860  ? 186.526 212.102 199.284 1.00 56.82  ? 871  VAL A CA  1 
ATOM   2303 C C   . VAL A 1 860  ? 187.701 212.003 198.319 1.00 56.82  ? 871  VAL A C   1 
ATOM   2304 O O   . VAL A 1 860  ? 188.824 212.397 198.650 1.00 56.82  ? 871  VAL A O   1 
ATOM   2305 C CB  . VAL A 1 860  ? 185.924 213.525 199.291 1.00 56.82  ? 871  VAL A CB  1 
ATOM   2306 C CG1 . VAL A 1 860  ? 186.881 214.512 199.945 1.00 56.82  ? 871  VAL A CG1 1 
ATOM   2307 C CG2 . VAL A 1 860  ? 185.566 213.968 197.881 1.00 56.82  ? 871  VAL A CG2 1 
ATOM   2308 N N   . GLY A 1 861  ? 187.445 211.465 197.131 1.00 59.07  ? 872  GLY A N   1 
ATOM   2309 C CA  . GLY A 1 861  ? 188.498 211.332 196.140 1.00 59.07  ? 872  GLY A CA  1 
ATOM   2310 C C   . GLY A 1 861  ? 187.930 210.951 194.792 1.00 59.07  ? 872  GLY A C   1 
ATOM   2311 O O   . GLY A 1 861  ? 186.746 210.631 194.656 1.00 59.07  ? 872  GLY A O   1 
ATOM   2312 N N   . TRP A 1 862  ? 188.805 210.995 193.789 1.00 62.18  ? 873  TRP A N   1 
ATOM   2313 C CA  . TRP A 1 862  ? 188.450 210.658 192.420 1.00 62.18  ? 873  TRP A CA  1 
ATOM   2314 C C   . TRP A 1 862  ? 189.547 209.791 191.821 1.00 62.18  ? 873  TRP A C   1 
ATOM   2315 O O   . TRP A 1 862  ? 190.726 209.946 192.147 1.00 62.18  ? 873  TRP A O   1 
ATOM   2316 C CB  . TRP A 1 862  ? 188.239 211.921 191.571 1.00 62.18  ? 873  TRP A CB  1 
ATOM   2317 C CG  . TRP A 1 862  ? 188.017 211.652 190.115 1.00 62.18  ? 873  TRP A CG  1 
ATOM   2318 C CD1 . TRP A 1 862  ? 186.825 211.410 189.499 1.00 62.18  ? 873  TRP A CD1 1 
ATOM   2319 C CD2 . TRP A 1 862  ? 189.015 211.610 189.089 1.00 62.18  ? 873  TRP A CD2 1 
ATOM   2320 N NE1 . TRP A 1 862  ? 187.019 211.214 188.153 1.00 62.18  ? 873  TRP A NE1 1 
ATOM   2321 C CE2 . TRP A 1 862  ? 188.355 211.331 187.876 1.00 62.18  ? 873  TRP A CE2 1 
ATOM   2322 C CE3 . TRP A 1 862  ? 190.403 211.777 189.079 1.00 62.18  ? 873  TRP A CE3 1 
ATOM   2323 C CZ2 . TRP A 1 862  ? 189.035 211.217 186.667 1.00 62.18  ? 873  TRP A CZ2 1 
ATOM   2324 C CZ3 . TRP A 1 862  ? 191.075 211.663 187.877 1.00 62.18  ? 873  TRP A CZ3 1 
ATOM   2325 C CH2 . TRP A 1 862  ? 190.391 211.386 186.688 1.00 62.18  ? 873  TRP A CH2 1 
ATOM   2326 N N   . ARG A 1 863  ? 189.149 208.875 190.941 1.00 65.78  ? 874  ARG A N   1 
ATOM   2327 C CA  . ARG A 1 863  ? 190.090 207.940 190.345 1.00 65.78  ? 874  ARG A CA  1 
ATOM   2328 C C   . ARG A 1 863  ? 189.634 207.592 188.936 1.00 65.78  ? 874  ARG A C   1 
ATOM   2329 O O   . ARG A 1 863  ? 188.459 207.737 188.588 1.00 65.78  ? 874  ARG A O   1 
ATOM   2330 C CB  . ARG A 1 863  ? 190.224 206.666 191.189 1.00 65.78  ? 874  ARG A CB  1 
ATOM   2331 C CG  . ARG A 1 863  ? 189.215 205.582 190.841 1.00 65.78  ? 874  ARG A CG  1 
ATOM   2332 C CD  . ARG A 1 863  ? 189.174 204.495 191.903 1.00 65.78  ? 874  ARG A CD  1 
ATOM   2333 N NE  . ARG A 1 863  ? 187.862 203.864 191.982 1.00 65.78  ? 874  ARG A NE  1 
ATOM   2334 C CZ  . ARG A 1 863  ? 186.926 204.189 192.863 1.00 65.78  ? 874  ARG A CZ  1 
ATOM   2335 N NH1 . ARG A 1 863  ? 187.122 205.140 193.761 1.00 65.78  ? 874  ARG A NH1 1 
ATOM   2336 N NH2 . ARG A 1 863  ? 185.762 203.545 192.840 1.00 65.78  ? 874  ARG A NH2 1 
ATOM   2337 N N   . ASN A 1 864  ? 190.581 207.130 188.129 1.00 68.57  ? 875  ASN A N   1 
ATOM   2338 C CA  . ASN A 1 864  ? 190.287 206.635 186.789 1.00 68.57  ? 875  ASN A CA  1 
ATOM   2339 C C   . ASN A 1 864  ? 191.300 205.541 186.462 1.00 68.57  ? 875  ASN A C   1 
ATOM   2340 O O   . ASN A 1 864  ? 191.961 205.004 187.357 1.00 68.57  ? 875  ASN A O   1 
ATOM   2341 C CB  . ASN A 1 864  ? 190.277 207.788 185.765 1.00 68.57  ? 875  ASN A CB  1 
ATOM   2342 C CG  . ASN A 1 864  ? 191.650 208.402 185.540 1.00 68.57  ? 875  ASN A CG  1 
ATOM   2343 O OD1 . ASN A 1 864  ? 192.631 208.032 186.182 1.00 68.57  ? 875  ASN A OD1 1 
ATOM   2344 N ND2 . ASN A 1 864  ? 191.722 209.347 184.610 1.00 68.57  ? 875  ASN A ND2 1 
ATOM   2345 N N   . ASP A 1 865  ? 191.420 205.205 185.177 1.00 72.11  ? 876  ASP A N   1 
ATOM   2346 C CA  . ASP A 1 865  ? 192.344 204.151 184.773 1.00 72.11  ? 876  ASP A CA  1 
ATOM   2347 C C   . ASP A 1 865  ? 193.799 204.587 184.900 1.00 72.11  ? 876  ASP A C   1 
ATOM   2348 O O   . ASP A 1 865  ? 194.676 203.747 185.132 1.00 72.11  ? 876  ASP A O   1 
ATOM   2349 C CB  . ASP A 1 865  ? 192.039 203.717 183.338 1.00 72.11  ? 876  ASP A CB  1 
ATOM   2350 C CG  . ASP A 1 865  ? 193.151 202.884 182.729 1.00 72.11  ? 876  ASP A CG  1 
ATOM   2351 O OD1 . ASP A 1 865  ? 193.494 201.833 183.310 1.00 72.11  ? 876  ASP A OD1 1 
ATOM   2352 O OD2 . ASP A 1 865  ? 193.682 203.281 181.671 1.00 72.11  ? 876  ASP A OD2 1 
ATOM   2353 N N   . VAL A 1 866  ? 194.078 205.883 184.771 1.00 68.41  ? 877  VAL A N   1 
ATOM   2354 C CA  . VAL A 1 866  ? 195.456 206.358 184.697 1.00 68.41  ? 877  VAL A CA  1 
ATOM   2355 C C   . VAL A 1 866  ? 195.983 206.736 186.075 1.00 68.41  ? 877  VAL A C   1 
ATOM   2356 O O   . VAL A 1 866  ? 196.954 206.145 186.561 1.00 68.41  ? 877  VAL A O   1 
ATOM   2357 C CB  . VAL A 1 866  ? 195.576 207.546 183.724 1.00 68.41  ? 877  VAL A CB  1 
ATOM   2358 C CG1 . VAL A 1 866  ? 196.970 208.151 183.796 1.00 68.41  ? 877  VAL A CG1 1 
ATOM   2359 C CG2 . VAL A 1 866  ? 195.255 207.103 182.306 1.00 68.41  ? 877  VAL A CG2 1 
ATOM   2360 N N   . TRP A 1 867  ? 195.355 207.720 186.717 1.00 68.25  ? 878  TRP A N   1 
ATOM   2361 C CA  . TRP A 1 867  ? 195.851 208.263 187.974 1.00 68.25  ? 878  TRP A CA  1 
ATOM   2362 C C   . TRP A 1 867  ? 194.717 208.404 188.978 1.00 68.25  ? 878  TRP A C   1 
ATOM   2363 O O   . TRP A 1 867  ? 193.589 208.750 188.614 1.00 68.25  ? 878  TRP A O   1 
ATOM   2364 C CB  . TRP A 1 867  ? 196.537 209.621 187.756 1.00 68.25  ? 878  TRP A CB  1 
ATOM   2365 C CG  . TRP A 1 867  ? 195.601 210.730 187.382 1.00 68.25  ? 878  TRP A CG  1 
ATOM   2366 C CD1 . TRP A 1 867  ? 194.669 210.717 186.386 1.00 68.25  ? 878  TRP A CD1 1 
ATOM   2367 C CD2 . TRP A 1 867  ? 195.518 212.025 187.991 1.00 68.25  ? 878  TRP A CD2 1 
ATOM   2368 N NE1 . TRP A 1 867  ? 194.006 211.918 186.341 1.00 68.25  ? 878  TRP A NE1 1 
ATOM   2369 C CE2 . TRP A 1 867  ? 194.508 212.739 187.316 1.00 68.25  ? 878  TRP A CE2 1 
ATOM   2370 C CE3 . TRP A 1 867  ? 196.197 212.647 189.042 1.00 68.25  ? 878  TRP A CE3 1 
ATOM   2371 C CZ2 . TRP A 1 867  ? 194.161 214.044 187.659 1.00 68.25  ? 878  TRP A CZ2 1 
ATOM   2372 C CZ3 . TRP A 1 867  ? 195.851 213.943 189.381 1.00 68.25  ? 878  TRP A CZ3 1 
ATOM   2373 C CH2 . TRP A 1 867  ? 194.842 214.627 188.691 1.00 68.25  ? 878  TRP A CH2 1 
ATOM   2374 N N   . SER A 1 868  ? 195.027 208.143 190.246 1.00 64.13  ? 879  SER A N   1 
ATOM   2375 C CA  . SER A 1 868  ? 194.048 208.193 191.320 1.00 64.13  ? 879  SER A CA  1 
ATOM   2376 C C   . SER A 1 868  ? 194.558 209.085 192.443 1.00 64.13  ? 879  SER A C   1 
ATOM   2377 O O   . SER A 1 868  ? 195.764 209.215 192.664 1.00 64.13  ? 879  SER A O   1 
ATOM   2378 C CB  . SER A 1 868  ? 193.741 206.791 191.864 1.00 64.13  ? 879  SER A CB  1 
ATOM   2379 O OG  . SER A 1 868  ? 193.555 205.864 190.810 1.00 64.13  ? 879  SER A OG  1 
ATOM   2380 N N   . TRP A 1 869  ? 193.616 209.701 193.154 1.00 56.64  ? 880  TRP A N   1 
ATOM   2381 C CA  . TRP A 1 869  ? 193.949 210.544 194.292 1.00 56.64  ? 880  TRP A CA  1 
ATOM   2382 C C   . TRP A 1 869  ? 192.771 210.555 195.253 1.00 56.64  ? 880  TRP A C   1 
ATOM   2383 O O   . TRP A 1 869  ? 191.626 210.328 194.854 1.00 56.64  ? 880  TRP A O   1 
ATOM   2384 C CB  . TRP A 1 869  ? 194.294 211.973 193.856 1.00 56.64  ? 880  TRP A CB  1 
ATOM   2385 C CG  . TRP A 1 869  ? 193.125 212.733 193.308 1.00 56.64  ? 880  TRP A CG  1 
ATOM   2386 C CD1 . TRP A 1 869  ? 192.712 212.776 192.009 1.00 56.64  ? 880  TRP A CD1 1 
ATOM   2387 C CD2 . TRP A 1 869  ? 192.218 213.563 194.045 1.00 56.64  ? 880  TRP A CD2 1 
ATOM   2388 N NE1 . TRP A 1 869  ? 191.604 213.579 191.891 1.00 56.64  ? 880  TRP A NE1 1 
ATOM   2389 C CE2 . TRP A 1 869  ? 191.281 214.074 193.127 1.00 56.64  ? 880  TRP A CE2 1 
ATOM   2390 C CE3 . TRP A 1 869  ? 192.108 213.921 195.391 1.00 56.64  ? 880  TRP A CE3 1 
ATOM   2391 C CZ2 . TRP A 1 869  ? 190.247 214.926 193.511 1.00 56.64  ? 880  TRP A CZ2 1 
ATOM   2392 C CZ3 . TRP A 1 869  ? 191.081 214.767 195.771 1.00 56.64  ? 880  TRP A CZ3 1 
ATOM   2393 C CH2 . TRP A 1 869  ? 190.165 215.259 194.835 1.00 56.64  ? 880  TRP A CH2 1 
ATOM   2394 N N   . ASP A 1 870  ? 193.066 210.822 196.523 1.00 55.67  ? 881  ASP A N   1 
ATOM   2395 C CA  . ASP A 1 870  ? 192.035 210.896 197.547 1.00 55.67  ? 881  ASP A CA  1 
ATOM   2396 C C   . ASP A 1 870  ? 192.547 211.727 198.714 1.00 55.67  ? 881  ASP A C   1 
ATOM   2397 O O   . ASP A 1 870  ? 193.752 211.940 198.870 1.00 55.67  ? 881  ASP A O   1 
ATOM   2398 C CB  . ASP A 1 870  ? 191.603 209.499 198.016 1.00 55.67  ? 881  ASP A CB  1 
ATOM   2399 C CG  . ASP A 1 870  ? 192.666 208.802 198.847 1.00 55.67  ? 881  ASP A CG  1 
ATOM   2400 O OD1 . ASP A 1 870  ? 193.866 209.096 198.662 1.00 55.67  ? 881  ASP A OD1 1 
ATOM   2401 O OD2 . ASP A 1 870  ? 192.298 207.956 199.688 1.00 55.67  ? 881  ASP A OD2 1 
ATOM   2402 N N   . ILE A 1 871  ? 191.611 212.198 199.533 1.00 53.93  ? 882  ILE A N   1 
ATOM   2403 C CA  . ILE A 1 871  ? 191.938 213.000 200.706 1.00 53.93  ? 882  ILE A CA  1 
ATOM   2404 C C   . ILE A 1 871  ? 190.893 212.726 201.779 1.00 53.93  ? 882  ILE A C   1 
ATOM   2405 O O   . ILE A 1 871  ? 189.719 212.492 201.477 1.00 53.93  ? 882  ILE A O   1 
ATOM   2406 C CB  . ILE A 1 871  ? 192.025 214.503 200.358 1.00 53.93  ? 882  ILE A CB  1 
ATOM   2407 C CG1 . ILE A 1 871  ? 192.592 215.299 201.535 1.00 53.93  ? 882  ILE A CG1 1 
ATOM   2408 C CG2 . ILE A 1 871  ? 190.666 215.045 199.937 1.00 53.93  ? 882  ILE A CG2 1 
ATOM   2409 C CD1 . ILE A 1 871  ? 192.936 216.732 201.194 1.00 53.93  ? 882  ILE A CD1 1 
ATOM   2410 N N   . GLY A 1 872  ? 191.329 212.738 203.031 1.00 54.24  ? 883  GLY A N   1 
ATOM   2411 C CA  . GLY A 1 872  ? 190.423 212.483 204.129 1.00 54.24  ? 883  GLY A CA  1 
ATOM   2412 C C   . GLY A 1 872  ? 191.073 212.807 205.454 1.00 54.24  ? 883  GLY A C   1 
ATOM   2413 O O   . GLY A 1 872  ? 192.183 213.339 205.511 1.00 54.24  ? 883  GLY A O   1 
ATOM   2414 N N   . THR A 1 873  ? 190.358 212.481 206.527 1.00 56.81  ? 884  THR A N   1 
ATOM   2415 C CA  . THR A 1 873  ? 190.826 212.734 207.880 1.00 56.81  ? 884  THR A CA  1 
ATOM   2416 C C   . THR A 1 873  ? 190.723 211.460 208.706 1.00 56.81  ? 884  THR A C   1 
ATOM   2417 O O   . THR A 1 873  ? 189.926 210.565 208.414 1.00 56.81  ? 884  THR A O   1 
ATOM   2418 C CB  . THR A 1 873  ? 190.026 213.853 208.568 1.00 56.81  ? 884  THR A CB  1 
ATOM   2419 O OG1 . THR A 1 873  ? 188.717 213.374 208.900 1.00 56.81  ? 884  THR A OG1 1 
ATOM   2420 C CG2 . THR A 1 873  ? 189.905 215.070 207.662 1.00 56.81  ? 884  THR A CG2 1 
ATOM   2421 N N   . THR A 1 874  ? 191.540 211.402 209.761 1.00 61.28  ? 885  THR A N   1 
ATOM   2422 C CA  . THR A 1 874  ? 191.467 210.256 210.687 1.00 61.28  ? 885  THR A CA  1 
ATOM   2423 C C   . THR A 1 874  ? 190.204 210.406 211.498 1.00 61.28  ? 885  THR A C   1 
ATOM   2424 O O   . THR A 1 874  ? 189.723 211.547 211.651 1.00 61.28  ? 885  THR A O   1 
ATOM   2425 C CB  . THR A 1 874  ? 192.706 210.214 211.579 1.00 61.28  ? 885  THR A CB  1 
ATOM   2426 O OG1 . THR A 1 874  ? 192.831 211.536 212.091 1.00 61.28  ? 885  THR A OG1 1 
ATOM   2427 C CG2 . THR A 1 874  ? 193.961 209.829 210.820 1.00 61.28  ? 885  THR A CG2 1 
ATOM   2428 N N   . PRO A 1 875  ? 189.635 209.313 212.035 1.00 61.48  ? 886  PRO A N   1 
ATOM   2429 C CA  . PRO A 1 875  ? 188.352 209.356 212.753 1.00 61.48  ? 886  PRO A CA  1 
ATOM   2430 C C   . PRO A 1 875  ? 188.280 210.446 213.811 1.00 61.48  ? 886  PRO A C   1 
ATOM   2431 O O   . PRO A 1 875  ? 189.020 210.420 214.800 1.00 61.48  ? 886  PRO A O   1 
ATOM   2432 C CB  . PRO A 1 875  ? 188.266 207.961 213.382 1.00 61.48  ? 886  PRO A CB  1 
ATOM   2433 C CG  . PRO A 1 875  ? 189.014 207.095 212.434 1.00 61.48  ? 886  PRO A CG  1 
ATOM   2434 C CD  . PRO A 1 875  ? 190.156 207.937 211.930 1.00 61.48  ? 886  PRO A CD  1 
ATOM   2435 N N   . MET A 1 876  ? 187.387 211.410 213.603 1.00 65.25  ? 887  MET A N   1 
ATOM   2436 C CA  . MET A 1 876  ? 187.230 212.510 214.545 1.00 65.25  ? 887  MET A CA  1 
ATOM   2437 C C   . MET A 1 876  ? 186.552 212.017 215.816 1.00 65.25  ? 887  MET A C   1 
ATOM   2438 O O   . MET A 1 876  ? 185.522 211.340 215.763 1.00 65.25  ? 887  MET A O   1 
ATOM   2439 C CB  . MET A 1 876  ? 186.417 213.637 213.910 1.00 65.25  ? 887  MET A CB  1 
ATOM   2440 C CG  . MET A 1 876  ? 186.019 214.739 214.877 1.00 65.25  ? 887  MET A CG  1 
ATOM   2441 S SD  . MET A 1 876  ? 185.722 216.312 214.047 1.00 65.25  ? 887  MET A SD  1 
ATOM   2442 C CE  . MET A 1 876  ? 186.117 217.466 215.359 1.00 65.25  ? 887  MET A CE  1 
ATOM   2443 N N   . GLY A 1 877  ? 187.129 212.368 216.962 1.00 66.38  ? 888  GLY A N   1 
ATOM   2444 C CA  . GLY A 1 877  ? 186.635 211.888 218.237 1.00 66.38  ? 888  GLY A CA  1 
ATOM   2445 C C   . GLY A 1 877  ? 187.709 211.156 219.012 1.00 66.38  ? 888  GLY A C   1 
ATOM   2446 O O   . GLY A 1 877  ? 187.611 210.995 220.232 1.00 66.38  ? 888  GLY A O   1 
ATOM   2447 N N   . PHE A 1 878  ? 188.741 210.705 218.304 1.00 62.41  ? 889  PHE A N   1 
ATOM   2448 C CA  . PHE A 1 878  ? 189.869 210.052 218.943 1.00 62.41  ? 889  PHE A CA  1 
ATOM   2449 C C   . PHE A 1 878  ? 190.753 211.086 219.640 1.00 62.41  ? 889  PHE A C   1 
ATOM   2450 O O   . PHE A 1 878  ? 190.591 212.299 219.477 1.00 62.41  ? 889  PHE A O   1 
ATOM   2451 C CB  . PHE A 1 878  ? 190.679 209.258 217.919 1.00 62.41  ? 889  PHE A CB  1 
ATOM   2452 C CG  . PHE A 1 878  ? 190.105 207.906 217.608 1.00 62.41  ? 889  PHE A CG  1 
ATOM   2453 C CD1 . PHE A 1 878  ? 189.085 207.377 218.381 1.00 62.41  ? 889  PHE A CD1 1 
ATOM   2454 C CD2 . PHE A 1 878  ? 190.584 207.164 216.542 1.00 62.41  ? 889  PHE A CD2 1 
ATOM   2455 C CE1 . PHE A 1 878  ? 188.556 206.133 218.097 1.00 62.41  ? 889  PHE A CE1 1 
ATOM   2456 C CE2 . PHE A 1 878  ? 190.059 205.920 216.253 1.00 62.41  ? 889  PHE A CE2 1 
ATOM   2457 C CZ  . PHE A 1 878  ? 189.044 205.404 217.032 1.00 62.41  ? 889  PHE A CZ  1 
ATOM   2458 N N   . ASN A 1 879  ? 191.698 210.584 220.437 1.00 63.78  ? 890  ASN A N   1 
ATOM   2459 C CA  . ASN A 1 879  ? 192.598 211.472 221.167 1.00 63.78  ? 890  ASN A CA  1 
ATOM   2460 C C   . ASN A 1 879  ? 193.461 212.292 220.216 1.00 63.78  ? 890  ASN A C   1 
ATOM   2461 O O   . ASN A 1 879  ? 193.685 213.487 220.442 1.00 63.78  ? 890  ASN A O   1 
ATOM   2462 C CB  . ASN A 1 879  ? 193.471 210.660 222.123 1.00 63.78  ? 890  ASN A CB  1 
ATOM   2463 C CG  . ASN A 1 879  ? 192.713 210.194 223.349 1.00 63.78  ? 890  ASN A CG  1 
ATOM   2464 O OD1 . ASN A 1 879  ? 192.203 211.005 224.122 1.00 63.78  ? 890  ASN A OD1 1 
ATOM   2465 N ND2 . ASN A 1 879  ? 192.632 208.882 223.533 1.00 63.78  ? 890  ASN A ND2 1 
ATOM   2466 N N   . VAL A 1 880  ? 193.955 211.670 219.148 1.00 62.60  ? 891  VAL A N   1 
ATOM   2467 C CA  . VAL A 1 880  ? 194.790 212.334 218.155 1.00 62.60  ? 891  VAL A CA  1 
ATOM   2468 C C   . VAL A 1 880  ? 194.101 212.232 216.802 1.00 62.60  ? 891  VAL A C   1 
ATOM   2469 O O   . VAL A 1 880  ? 193.707 211.138 216.382 1.00 62.60  ? 891  VAL A O   1 
ATOM   2470 C CB  . VAL A 1 880  ? 196.201 211.722 218.095 1.00 62.60  ? 891  VAL A CB  1 
ATOM   2471 C CG1 . VAL A 1 880  ? 197.085 212.521 217.150 1.00 62.60  ? 891  VAL A CG1 1 
ATOM   2472 C CG2 . VAL A 1 880  ? 196.814 211.665 219.486 1.00 62.60  ? 891  VAL A CG2 1 
ATOM   2473 N N   . VAL A 1 881  ? 193.957 213.369 216.126 1.00 62.23  ? 892  VAL A N   1 
ATOM   2474 C CA  . VAL A 1 881  ? 193.321 213.441 214.816 1.00 62.23  ? 892  VAL A CA  1 
ATOM   2475 C C   . VAL A 1 881  ? 194.294 214.081 213.835 1.00 62.23  ? 892  VAL A C   1 
ATOM   2476 O O   . VAL A 1 881  ? 195.010 215.028 214.181 1.00 62.23  ? 892  VAL A O   1 
ATOM   2477 C CB  . VAL A 1 881  ? 191.985 214.215 214.873 1.00 62.23  ? 892  VAL A CB  1 
ATOM   2478 C CG1 . VAL A 1 881  ? 192.209 215.677 215.238 1.00 62.23  ? 892  VAL A CG1 1 
ATOM   2479 C CG2 . VAL A 1 881  ? 191.238 214.095 213.553 1.00 62.23  ? 892  VAL A CG2 1 
ATOM   2480 N N   . ASP A 1 882  ? 194.340 213.542 212.619 1.00 60.84  ? 893  ASP A N   1 
ATOM   2481 C CA  . ASP A 1 882  ? 195.236 214.031 211.582 1.00 60.84  ? 893  ASP A CA  1 
ATOM   2482 C C   . ASP A 1 882  ? 194.552 213.906 210.228 1.00 60.84  ? 893  ASP A C   1 
ATOM   2483 O O   . ASP A 1 882  ? 193.607 213.134 210.055 1.00 60.84  ? 893  ASP A O   1 
ATOM   2484 C CB  . ASP A 1 882  ? 196.567 213.267 211.575 1.00 60.84  ? 893  ASP A CB  1 
ATOM   2485 C CG  . ASP A 1 882  ? 197.485 213.682 212.708 1.00 60.84  ? 893  ASP A CG  1 
ATOM   2486 O OD1 . ASP A 1 882  ? 197.584 214.897 212.980 1.00 60.84  ? 893  ASP A OD1 1 
ATOM   2487 O OD2 . ASP A 1 882  ? 198.106 212.794 213.328 1.00 60.84  ? 893  ASP A OD2 1 
ATOM   2488 N N   . VAL A 1 883  ? 195.060 214.704 209.277 1.00 56.76  ? 894  VAL A N   1 
ATOM   2489 C CA  . VAL A 1 883  ? 194.497 214.714 207.895 1.00 56.76  ? 894  VAL A CA  1 
ATOM   2490 C C   . VAL A 1 883  ? 195.376 213.831 207.003 1.00 56.76  ? 894  VAL A C   1 
ATOM   2491 O O   . VAL A 1 883  ? 196.528 214.218 206.724 1.00 56.76  ? 894  VAL A O   1 
ATOM   2492 C CB  . VAL A 1 883  ? 194.390 216.145 207.335 1.00 56.76  ? 894  VAL A CB  1 
ATOM   2493 C CG1 . VAL A 1 883  ? 195.591 217.005 207.710 1.00 56.76  ? 894  VAL A CG1 1 
ATOM   2494 C CG2 . VAL A 1 883  ? 194.147 216.158 205.831 1.00 56.76  ? 894  VAL A CG2 1 
ATOM   2495 N N   . VAL A 1 884  ? 194.848 212.686 206.592 1.00 55.51  ? 895  VAL A N   1 
ATOM   2496 C CA  . VAL A 1 884  ? 195.568 211.756 205.730 1.00 55.51  ? 895  VAL A CA  1 
ATOM   2497 C C   . VAL A 1 884  ? 195.364 212.150 204.273 1.00 55.51  ? 895  VAL A C   1 
ATOM   2498 O O   . VAL A 1 884  ? 194.486 212.959 203.953 1.00 55.51  ? 895  VAL A O   1 
ATOM   2499 C CB  . VAL A 1 884  ? 195.119 210.306 205.979 1.00 55.51  ? 895  VAL A CB  1 
ATOM   2500 C CG1 . VAL A 1 884  ? 195.038 210.027 207.471 1.00 55.51  ? 895  VAL A CG1 1 
ATOM   2501 C CG2 . VAL A 1 884  ? 193.783 210.043 205.310 1.00 55.51  ? 895  VAL A CG2 1 
ATOM   2502 N N   . GLY A 1 885  ? 196.178 211.589 203.383 1.00 52.38  ? 896  GLY A N   1 
ATOM   2503 C CA  . GLY A 1 885  ? 196.047 211.863 201.966 1.00 52.38  ? 896  GLY A CA  1 
ATOM   2504 C C   . GLY A 1 885  ? 196.760 210.805 201.154 1.00 52.38  ? 896  GLY A C   1 
ATOM   2505 O O   . GLY A 1 885  ? 197.439 209.928 201.693 1.00 52.38  ? 896  GLY A O   1 
ATOM   2506 N N   . GLY A 1 886  ? 196.595 210.897 199.840 1.00 54.50  ? 897  GLY A N   1 
ATOM   2507 C CA  . GLY A 1 886  ? 197.228 209.949 198.945 1.00 54.50  ? 897  GLY A CA  1 
ATOM   2508 C C   . GLY A 1 886  ? 197.073 210.367 197.502 1.00 54.50  ? 897  GLY A C   1 
ATOM   2509 O O   . GLY A 1 886  ? 196.224 211.198 197.160 1.00 54.50  ? 897  GLY A O   1 
ATOM   2510 N N   . ILE A 1 887  ? 197.911 209.770 196.655 1.00 54.20  ? 898  ILE A N   1 
ATOM   2511 C CA  . ILE A 1 887  ? 197.886 210.023 195.219 1.00 54.20  ? 898  ILE A CA  1 
ATOM   2512 C C   . ILE A 1 887  ? 198.606 208.867 194.543 1.00 54.20  ? 898  ILE A C   1 
ATOM   2513 O O   . ILE A 1 887  ? 199.490 208.240 195.133 1.00 54.20  ? 898  ILE A O   1 
ATOM   2514 C CB  . ILE A 1 887  ? 198.528 211.392 194.875 1.00 54.20  ? 898  ILE A CB  1 
ATOM   2515 C CG1 . ILE A 1 887  ? 198.192 211.803 193.440 1.00 54.20  ? 898  ILE A CG1 1 
ATOM   2516 C CG2 . ILE A 1 887  ? 200.032 211.354 195.090 1.00 54.20  ? 898  ILE A CG2 1 
ATOM   2517 C CD1 . ILE A 1 887  ? 198.761 213.146 193.042 1.00 54.20  ? 898  ILE A CD1 1 
ATOM   2518 N N   . SER A 1 888  ? 198.216 208.573 193.304 1.00 58.81  ? 899  SER A N   1 
ATOM   2519 C CA  . SER A 1 888  ? 198.794 207.449 192.584 1.00 58.81  ? 899  SER A CA  1 
ATOM   2520 C C   . SER A 1 888  ? 198.785 207.732 191.090 1.00 58.81  ? 899  SER A C   1 
ATOM   2521 O O   . SER A 1 888  ? 197.973 208.518 190.594 1.00 58.81  ? 899  SER A O   1 
ATOM   2522 C CB  . SER A 1 888  ? 198.039 206.147 192.878 1.00 58.81  ? 899  SER A CB  1 
ATOM   2523 O OG  . SER A 1 888  ? 198.430 205.119 191.985 1.00 58.81  ? 899  SER A OG  1 
ATOM   2524 N N   . TYR A 1 889  ? 199.702 207.078 190.380 1.00 64.85  ? 900  TYR A N   1 
ATOM   2525 C CA  . TYR A 1 889  ? 199.794 207.167 188.931 1.00 64.85  ? 900  TYR A CA  1 
ATOM   2526 C C   . TYR A 1 889  ? 200.116 205.788 188.374 1.00 64.85  ? 900  TYR A C   1 
ATOM   2527 O O   . TYR A 1 889  ? 200.869 205.021 188.978 1.00 64.85  ? 900  TYR A O   1 
ATOM   2528 C CB  . TYR A 1 889  ? 200.861 208.181 188.494 1.00 64.85  ? 900  TYR A CB  1 
ATOM   2529 C CG  . TYR A 1 889  ? 201.106 208.218 187.003 1.00 64.85  ? 900  TYR A CG  1 
ATOM   2530 C CD1 . TYR A 1 889  ? 200.242 208.895 186.154 1.00 64.85  ? 900  TYR A CD1 1 
ATOM   2531 C CD2 . TYR A 1 889  ? 202.206 207.580 186.445 1.00 64.85  ? 900  TYR A CD2 1 
ATOM   2532 C CE1 . TYR A 1 889  ? 200.463 208.932 184.790 1.00 64.85  ? 900  TYR A CE1 1 
ATOM   2533 C CE2 . TYR A 1 889  ? 202.435 207.611 185.083 1.00 64.85  ? 900  TYR A CE2 1 
ATOM   2534 C CZ  . TYR A 1 889  ? 201.561 208.289 184.261 1.00 64.85  ? 900  TYR A CZ  1 
ATOM   2535 O OH  . TYR A 1 889  ? 201.786 208.323 182.903 1.00 64.85  ? 900  TYR A OH  1 
ATOM   2536 N N   . SER A 1 890  ? 199.542 205.480 187.213 1.00 69.18  ? 901  SER A N   1 
ATOM   2537 C CA  . SER A 1 890  ? 199.735 204.177 186.595 1.00 69.18  ? 901  SER A CA  1 
ATOM   2538 C C   . SER A 1 890  ? 200.022 204.356 185.112 1.00 69.18  ? 901  SER A C   1 
ATOM   2539 O O   . SER A 1 890  ? 199.483 205.262 184.472 1.00 69.18  ? 901  SER A O   1 
ATOM   2540 C CB  . SER A 1 890  ? 198.508 203.278 186.788 1.00 69.18  ? 901  SER A CB  1 
ATOM   2541 O OG  . SER A 1 890  ? 198.239 203.071 188.164 1.00 69.18  ? 901  SER A OG  1 
ATOM   2542 N N   . ASP A 1 891  ? 200.871 203.483 184.577 1.00 76.31  ? 902  ASP A N   1 
ATOM   2543 C CA  . ASP A 1 891  ? 201.215 203.491 183.161 1.00 76.31  ? 902  ASP A CA  1 
ATOM   2544 C C   . ASP A 1 891  ? 201.796 202.126 182.811 1.00 76.31  ? 902  ASP A C   1 
ATOM   2545 O O   . ASP A 1 891  ? 201.906 201.240 183.662 1.00 76.31  ? 902  ASP A O   1 
ATOM   2546 C CB  . ASP A 1 891  ? 202.189 204.625 182.832 1.00 76.31  ? 902  ASP A CB  1 
ATOM   2547 C CG  . ASP A 1 891  ? 202.065 205.103 181.399 1.00 76.31  ? 902  ASP A CG  1 
ATOM   2548 O OD1 . ASP A 1 891  ? 201.244 204.532 180.650 1.00 76.31  ? 902  ASP A OD1 1 
ATOM   2549 O OD2 . ASP A 1 891  ? 202.788 206.048 181.020 1.00 76.31  ? 902  ASP A OD2 1 
ATOM   2550 N N   . ASP A 1 892  ? 202.169 201.962 181.544 1.00 81.18  ? 903  ASP A N   1 
ATOM   2551 C CA  . ASP A 1 892  ? 202.708 200.705 181.048 1.00 81.18  ? 903  ASP A CA  1 
ATOM   2552 C C   . ASP A 1 892  ? 203.997 200.960 180.281 1.00 81.18  ? 903  ASP A C   1 
ATOM   2553 O O   . ASP A 1 892  ? 204.082 201.901 179.487 1.00 81.18  ? 903  ASP A O   1 
ATOM   2554 C CB  . ASP A 1 892  ? 201.698 199.985 180.145 1.00 81.18  ? 903  ASP A CB  1 
ATOM   2555 C CG  . ASP A 1 892  ? 202.302 198.792 179.431 1.00 81.18  ? 903  ASP A CG  1 
ATOM   2556 O OD1 . ASP A 1 892  ? 203.014 198.005 180.088 1.00 81.18  ? 903  ASP A OD1 1 
ATOM   2557 O OD2 . ASP A 1 892  ? 202.068 198.644 178.213 1.00 81.18  ? 903  ASP A OD2 1 
ATOM   2558 N N   . ILE A 1 893  ? 204.996 200.115 180.525 1.00 82.29  ? 904  ILE A N   1 
ATOM   2559 C CA  . ILE A 1 893  ? 206.273 200.158 179.817 1.00 82.29  ? 904  ILE A CA  1 
ATOM   2560 C C   . ILE A 1 893  ? 206.491 198.764 179.243 1.00 82.29  ? 904  ILE A C   1 
ATOM   2561 O O   . ILE A 1 893  ? 206.847 197.834 179.975 1.00 82.29  ? 904  ILE A O   1 
ATOM   2562 C CB  . ILE A 1 893  ? 207.436 200.574 180.724 1.00 82.29  ? 904  ILE A CB  1 
ATOM   2563 C CG1 . ILE A 1 893  ? 207.257 202.018 181.193 1.00 82.29  ? 904  ILE A CG1 1 
ATOM   2564 C CG2 . ILE A 1 893  ? 208.763 200.415 179.996 1.00 82.29  ? 904  ILE A CG2 1 
ATOM   2565 C CD1 . ILE A 1 893  ? 208.403 202.532 182.038 1.00 82.29  ? 904  ILE A CD1 1 
ATOM   2566 N N   . GLY A 1 894  ? 206.285 198.615 177.936 1.00 82.03  ? 905  GLY A N   1 
ATOM   2567 C CA  . GLY A 1 894  ? 206.384 197.327 177.292 1.00 82.03  ? 905  GLY A CA  1 
ATOM   2568 C C   . GLY A 1 894  ? 205.409 196.329 177.882 1.00 82.03  ? 905  GLY A C   1 
ATOM   2569 O O   . GLY A 1 894  ? 204.204 196.583 177.973 1.00 82.03  ? 905  GLY A O   1 
ATOM   2570 N N   . PRO A 1 895  ? 205.913 195.166 178.289 1.00 80.88  ? 906  PRO A N   1 
ATOM   2571 C CA  . PRO A 1 895  ? 205.079 194.186 178.999 1.00 80.88  ? 906  PRO A CA  1 
ATOM   2572 C C   . PRO A 1 895  ? 205.037 194.360 180.511 1.00 80.88  ? 906  PRO A C   1 
ATOM   2573 O O   . PRO A 1 895  ? 204.490 193.490 181.194 1.00 80.88  ? 906  PRO A O   1 
ATOM   2574 C CB  . PRO A 1 895  ? 205.763 192.862 178.636 1.00 80.88  ? 906  PRO A CB  1 
ATOM   2575 C CG  . PRO A 1 895  ? 207.208 193.225 178.528 1.00 80.88  ? 906  PRO A CG  1 
ATOM   2576 C CD  . PRO A 1 895  ? 207.265 194.648 178.016 1.00 80.88  ? 906  PRO A CD  1 
ATOM   2577 N N   . LEU A 1 896  ? 205.591 195.447 181.043 1.00 79.17  ? 907  LEU A N   1 
ATOM   2578 C CA  . LEU A 1 896  ? 205.662 195.687 182.478 1.00 79.17  ? 907  LEU A CA  1 
ATOM   2579 C C   . LEU A 1 896  ? 204.832 196.912 182.832 1.00 79.17  ? 907  LEU A C   1 
ATOM   2580 O O   . LEU A 1 896  ? 204.965 197.962 182.194 1.00 79.17  ? 907  LEU A O   1 
ATOM   2581 C CB  . LEU A 1 896  ? 207.113 195.887 182.928 1.00 79.17  ? 907  LEU A CB  1 
ATOM   2582 C CG  . LEU A 1 896  ? 207.840 194.680 183.522 1.00 79.17  ? 907  LEU A CG  1 
ATOM   2583 C CD1 . LEU A 1 896  ? 209.328 194.962 183.640 1.00 79.17  ? 907  LEU A CD1 1 
ATOM   2584 C CD2 . LEU A 1 896  ? 207.257 194.328 184.879 1.00 79.17  ? 907  LEU A CD2 1 
ATOM   2585 N N   . GLY A 1 897  ? 203.984 196.777 183.846 1.00 73.05  ? 908  GLY A N   1 
ATOM   2586 C CA  . GLY A 1 897  ? 203.183 197.884 184.343 1.00 73.05  ? 908  GLY A CA  1 
ATOM   2587 C C   . GLY A 1 897  ? 203.690 198.353 185.696 1.00 73.05  ? 908  GLY A C   1 
ATOM   2588 O O   . GLY A 1 897  ? 203.982 197.543 186.576 1.00 73.05  ? 908  GLY A O   1 
ATOM   2589 N N   . TYR A 1 898  ? 203.788 199.671 185.851 1.00 69.28  ? 909  TYR A N   1 
ATOM   2590 C CA  . TYR A 1 898  ? 204.286 200.278 187.076 1.00 69.28  ? 909  TYR A CA  1 
ATOM   2591 C C   . TYR A 1 898  ? 203.259 201.260 187.617 1.00 69.28  ? 909  TYR A C   1 
ATOM   2592 O O   . TYR A 1 898  ? 202.659 202.027 186.858 1.00 69.28  ? 909  TYR A O   1 
ATOM   2593 C CB  . TYR A 1 898  ? 205.628 200.989 186.843 1.00 69.28  ? 909  TYR A CB  1 
ATOM   2594 C CG  . TYR A 1 898  ? 205.530 202.246 186.008 1.00 69.28  ? 909  TYR A CG  1 
ATOM   2595 C CD1 . TYR A 1 898  ? 205.408 202.178 184.627 1.00 69.28  ? 909  TYR A CD1 1 
ATOM   2596 C CD2 . TYR A 1 898  ? 205.562 203.502 186.602 1.00 69.28  ? 909  TYR A CD2 1 
ATOM   2597 C CE1 . TYR A 1 898  ? 205.319 203.324 183.861 1.00 69.28  ? 909  TYR A CE1 1 
ATOM   2598 C CE2 . TYR A 1 898  ? 205.473 204.653 185.843 1.00 69.28  ? 909  TYR A CE2 1 
ATOM   2599 C CZ  . TYR A 1 898  ? 205.352 204.558 184.474 1.00 69.28  ? 909  TYR A CZ  1 
ATOM   2600 O OH  . TYR A 1 898  ? 205.263 205.701 183.713 1.00 69.28  ? 909  TYR A OH  1 
ATOM   2601 N N   . THR A 1 899  ? 203.052 201.224 188.933 1.00 63.83  ? 910  THR A N   1 
ATOM   2602 C CA  . THR A 1 899  ? 202.104 202.105 189.616 1.00 63.83  ? 910  THR A CA  1 
ATOM   2603 C C   . THR A 1 899  ? 202.829 202.785 190.773 1.00 63.83  ? 910  THR A C   1 
ATOM   2604 O O   . THR A 1 899  ? 202.991 202.193 191.844 1.00 63.83  ? 910  THR A O   1 
ATOM   2605 C CB  . THR A 1 899  ? 200.881 201.337 190.118 1.00 63.83  ? 910  THR A CB  1 
ATOM   2606 O OG1 . THR A 1 899  ? 201.170 200.759 191.397 1.00 63.83  ? 910  THR A OG1 1 
ATOM   2607 C CG2 . THR A 1 899  ? 200.488 200.232 189.145 1.00 63.83  ? 910  THR A CG2 1 
ATOM   2608 N N   . VAL A 1 900  ? 203.264 204.027 190.560 1.00 57.02  ? 911  VAL A N   1 
ATOM   2609 C CA  . VAL A 1 900  ? 203.876 204.796 191.636 1.00 57.02  ? 911  VAL A CA  1 
ATOM   2610 C C   . VAL A 1 900  ? 202.791 205.498 192.446 1.00 57.02  ? 911  VAL A C   1 
ATOM   2611 O O   . VAL A 1 900  ? 201.692 205.777 191.958 1.00 57.02  ? 911  VAL A O   1 
ATOM   2612 C CB  . VAL A 1 900  ? 204.904 205.802 191.086 1.00 57.02  ? 911  VAL A CB  1 
ATOM   2613 C CG1 . VAL A 1 900  ? 205.892 205.101 190.169 1.00 57.02  ? 911  VAL A CG1 1 
ATOM   2614 C CG2 . VAL A 1 900  ? 204.204 206.937 190.356 1.00 57.02  ? 911  VAL A CG2 1 
ATOM   2615 N N   . ASN A 1 901  ? 203.104 205.782 193.708 1.00 54.84  ? 912  ASN A N   1 
ATOM   2616 C CA  . ASN A 1 901  ? 202.134 206.423 194.583 1.00 54.84  ? 912  ASN A CA  1 
ATOM   2617 C C   . ASN A 1 901  ? 202.845 207.058 195.769 1.00 54.84  ? 912  ASN A C   1 
ATOM   2618 O O   . ASN A 1 901  ? 203.905 206.596 196.198 1.00 54.84  ? 912  ASN A O   1 
ATOM   2619 C CB  . ASN A 1 901  ? 201.077 205.425 195.073 1.00 54.84  ? 912  ASN A CB  1 
ATOM   2620 C CG  . ASN A 1 901  ? 201.684 204.140 195.600 1.00 54.84  ? 912  ASN A CG  1 
ATOM   2621 O OD1 . ASN A 1 901  ? 202.904 203.995 195.664 1.00 54.84  ? 912  ASN A OD1 1 
ATOM   2622 N ND2 . ASN A 1 901  ? 200.831 203.197 195.983 1.00 54.84  ? 912  ASN A ND2 1 
ATOM   2623 N N   . ALA A 1 902  ? 202.244 208.128 196.285 1.00 53.52  ? 913  ALA A N   1 
ATOM   2624 C CA  . ALA A 1 902  ? 202.661 208.760 197.529 1.00 53.52  ? 913  ALA A CA  1 
ATOM   2625 C C   . ALA A 1 902  ? 201.446 208.847 198.437 1.00 53.52  ? 913  ALA A C   1 
ATOM   2626 O O   . ALA A 1 902  ? 200.419 209.414 198.048 1.00 53.52  ? 913  ALA A O   1 
ATOM   2627 C CB  . ALA A 1 902  ? 203.252 210.151 197.284 1.00 53.52  ? 913  ALA A CB  1 
ATOM   2628 N N   . HIS A 1 903  ? 201.559 208.292 199.642 1.00 55.53  ? 914  HIS A N   1 
ATOM   2629 C CA  . HIS A 1 903  ? 200.403 208.120 200.507 1.00 55.53  ? 914  HIS A CA  1 
ATOM   2630 C C   . HIS A 1 903  ? 200.732 208.547 201.929 1.00 55.53  ? 914  HIS A C   1 
ATOM   2631 O O   . HIS A 1 903  ? 201.890 208.529 202.352 1.00 55.53  ? 914  HIS A O   1 
ATOM   2632 C CB  . HIS A 1 903  ? 199.922 206.663 200.509 1.00 55.53  ? 914  HIS A CB  1 
ATOM   2633 C CG  . HIS A 1 903  ? 200.944 205.692 201.015 1.00 55.53  ? 914  HIS A CG  1 
ATOM   2634 N ND1 . HIS A 1 903  ? 201.846 205.061 200.186 1.00 55.53  ? 914  HIS A ND1 1 
ATOM   2635 C CD2 . HIS A 1 903  ? 201.208 205.248 202.266 1.00 55.53  ? 914  HIS A CD2 1 
ATOM   2636 C CE1 . HIS A 1 903  ? 202.621 204.268 200.904 1.00 55.53  ? 914  HIS A CE1 1 
ATOM   2637 N NE2 . HIS A 1 903  ? 202.255 204.363 202.169 1.00 55.53  ? 914  HIS A NE2 1 
ATOM   2638 N N   . ARG A 1 904  ? 199.688 208.934 202.659 1.00 51.84  ? 915  ARG A N   1 
ATOM   2639 C CA  . ARG A 1 904  ? 199.764 209.217 204.089 1.00 51.84  ? 915  ARG A CA  1 
ATOM   2640 C C   . ARG A 1 904  ? 198.695 208.379 204.774 1.00 51.84  ? 915  ARG A C   1 
ATOM   2641 O O   . ARG A 1 904  ? 197.499 208.646 204.615 1.00 51.84  ? 915  ARG A O   1 
ATOM   2642 C CB  . ARG A 1 904  ? 199.557 210.704 204.376 1.00 51.84  ? 915  ARG A CB  1 
ATOM   2643 C CG  . ARG A 1 904  ? 200.838 211.492 204.550 1.00 51.84  ? 915  ARG A CG  1 
ATOM   2644 C CD  . ARG A 1 904  ? 200.588 212.779 205.317 1.00 51.84  ? 915  ARG A CD  1 
ATOM   2645 N NE  . ARG A 1 904  ? 200.109 212.520 206.669 1.00 51.84  ? 915  ARG A NE  1 
ATOM   2646 C CZ  . ARG A 1 904  ? 200.499 213.191 207.744 1.00 51.84  ? 915  ARG A CZ  1 
ATOM   2647 N NH1 . ARG A 1 904  ? 201.379 214.175 207.663 1.00 51.84  ? 915  ARG A NH1 1 
ATOM   2648 N NH2 . ARG A 1 904  ? 199.993 212.867 208.930 1.00 51.84  ? 915  ARG A NH2 1 
ATOM   2649 N N   . ARG A 1 905  ? 199.114 207.369 205.528 1.00 57.41  ? 916  ARG A N   1 
ATOM   2650 C CA  . ARG A 1 905  ? 198.171 206.462 206.158 1.00 57.41  ? 916  ARG A CA  1 
ATOM   2651 C C   . ARG A 1 905  ? 198.526 206.256 207.622 1.00 57.41  ? 916  ARG A C   1 
ATOM   2652 O O   . ARG A 1 905  ? 199.705 206.269 207.990 1.00 57.41  ? 916  ARG A O   1 
ATOM   2653 C CB  . ARG A 1 905  ? 198.151 205.101 205.446 1.00 57.41  ? 916  ARG A CB  1 
ATOM   2654 C CG  . ARG A 1 905  ? 197.779 205.170 203.974 1.00 57.41  ? 916  ARG A CG  1 
ATOM   2655 C CD  . ARG A 1 905  ? 196.371 205.702 203.778 1.00 57.41  ? 916  ARG A CD  1 
ATOM   2656 N NE  . ARG A 1 905  ? 195.948 205.612 202.385 1.00 57.41  ? 916  ARG A NE  1 
ATOM   2657 C CZ  . ARG A 1 905  ? 195.353 206.591 201.718 1.00 57.41  ? 916  ARG A CZ  1 
ATOM   2658 N NH1 . ARG A 1 905  ? 195.094 207.757 202.287 1.00 57.41  ? 916  ARG A NH1 1 
ATOM   2659 N NH2 . ARG A 1 905  ? 195.011 206.396 200.448 1.00 57.41  ? 916  ARG A NH2 1 
ATOM   2660 N N   . PRO A 1 906  ? 197.527 206.064 208.476 1.00 55.23  ? 917  PRO A N   1 
ATOM   2661 C CA  . PRO A 1 906  ? 197.794 205.723 209.874 1.00 55.23  ? 917  PRO A CA  1 
ATOM   2662 C C   . PRO A 1 906  ? 197.949 204.217 210.049 1.00 55.23  ? 917  PRO A C   1 
ATOM   2663 O O   . PRO A 1 906  ? 197.834 203.434 209.106 1.00 55.23  ? 917  PRO A O   1 
ATOM   2664 C CB  . PRO A 1 906  ? 196.552 206.241 210.601 1.00 55.23  ? 917  PRO A CB  1 
ATOM   2665 C CG  . PRO A 1 906  ? 195.463 206.100 209.590 1.00 55.23  ? 917  PRO A CG  1 
ATOM   2666 C CD  . PRO A 1 906  ? 196.095 206.312 208.232 1.00 55.23  ? 917  PRO A CD  1 
ATOM   2667 N N   . ILE A 1 907  ? 198.216 203.822 211.290 1.00 55.52  ? 918  ILE A N   1 
ATOM   2668 C CA  . ILE A 1 907  ? 198.360 202.419 211.663 1.00 55.52  ? 918  ILE A CA  1 
ATOM   2669 C C   . ILE A 1 907  ? 197.141 202.023 212.484 1.00 55.52  ? 918  ILE A C   1 
ATOM   2670 O O   . ILE A 1 907  ? 196.892 202.593 213.553 1.00 55.52  ? 918  ILE A O   1 
ATOM   2671 C CB  . ILE A 1 907  ? 199.656 202.166 212.445 1.00 55.52  ? 918  ILE A CB  1 
ATOM   2672 C CG1 . ILE A 1 907  ? 200.868 202.625 211.635 1.00 55.52  ? 918  ILE A CG1 1 
ATOM   2673 C CG2 . ILE A 1 907  ? 199.781 200.695 212.804 1.00 55.52  ? 918  ILE A CG2 1 
ATOM   2674 C CD1 . ILE A 1 907  ? 202.186 202.280 212.282 1.00 55.52  ? 918  ILE A CD1 1 
ATOM   2675 N N   . SER A 1 908  ? 196.386 201.044 211.989 1.00 57.32  ? 919  SER A N   1 
ATOM   2676 C CA  . SER A 1 908  ? 195.179 200.574 212.653 1.00 57.32  ? 919  SER A CA  1 
ATOM   2677 C C   . SER A 1 908  ? 195.392 199.267 213.408 1.00 57.32  ? 919  SER A C   1 
ATOM   2678 O O   . SER A 1 908  ? 194.413 198.641 213.826 1.00 57.32  ? 919  SER A O   1 
ATOM   2679 C CB  . SER A 1 908  ? 194.049 200.410 211.636 1.00 57.32  ? 919  SER A CB  1 
ATOM   2680 O OG  . SER A 1 908  ? 194.430 199.539 210.585 1.00 57.32  ? 919  SER A OG  1 
ATOM   2681 N N   . SER A 1 909  ? 196.644 198.840 213.588 1.00 58.28  ? 920  SER A N   1 
ATOM   2682 C CA  . SER A 1 909  ? 196.908 197.589 214.289 1.00 58.28  ? 920  SER A CA  1 
ATOM   2683 C C   . SER A 1 909  ? 196.557 197.662 215.769 1.00 58.28  ? 920  SER A C   1 
ATOM   2684 O O   . SER A 1 909  ? 196.348 196.618 216.395 1.00 58.28  ? 920  SER A O   1 
ATOM   2685 C CB  . SER A 1 909  ? 198.376 197.192 214.125 1.00 58.28  ? 920  SER A CB  1 
ATOM   2686 O OG  . SER A 1 909  ? 199.232 198.129 214.755 1.00 58.28  ? 920  SER A OG  1 
ATOM   2687 N N   . SER A 1 910  ? 196.489 198.862 216.342 1.00 55.33  ? 921  SER A N   1 
ATOM   2688 C CA  . SER A 1 910  ? 196.169 199.017 217.753 1.00 55.33  ? 921  SER A CA  1 
ATOM   2689 C C   . SER A 1 910  ? 195.523 200.377 217.973 1.00 55.33  ? 921  SER A C   1 
ATOM   2690 O O   . SER A 1 910  ? 195.643 201.285 217.147 1.00 55.33  ? 921  SER A O   1 
ATOM   2691 C CB  . SER A 1 910  ? 197.416 198.866 218.632 1.00 55.33  ? 921  SER A CB  1 
ATOM   2692 O OG  . SER A 1 910  ? 198.226 200.026 218.568 1.00 55.33  ? 921  SER A OG  1 
ATOM   2693 N N   . LEU A 1 911  ? 194.827 200.502 219.106 1.00 57.21  ? 922  LEU A N   1 
ATOM   2694 C CA  . LEU A 1 911  ? 194.183 201.767 219.445 1.00 57.21  ? 922  LEU A CA  1 
ATOM   2695 C C   . LEU A 1 911  ? 195.209 202.874 219.646 1.00 57.21  ? 922  LEU A C   1 
ATOM   2696 O O   . LEU A 1 911  ? 194.996 204.015 219.218 1.00 57.21  ? 922  LEU A O   1 
ATOM   2697 C CB  . LEU A 1 911  ? 193.323 201.599 220.698 1.00 57.21  ? 922  LEU A CB  1 
ATOM   2698 C CG  . LEU A 1 911  ? 192.741 202.877 221.305 1.00 57.21  ? 922  LEU A CG  1 
ATOM   2699 C CD1 . LEU A 1 911  ? 191.826 203.579 220.315 1.00 57.21  ? 922  LEU A CD1 1 
ATOM   2700 C CD2 . LEU A 1 911  ? 192.002 202.570 222.597 1.00 57.21  ? 922  LEU A CD2 1 
ATOM   2701 N N   . LEU A 1 912  ? 196.329 202.557 220.300 1.00 55.37  ? 923  LEU A N   1 
ATOM   2702 C CA  . LEU A 1 912  ? 197.367 203.558 220.525 1.00 55.37  ? 923  LEU A CA  1 
ATOM   2703 C C   . LEU A 1 912  ? 197.951 204.053 219.208 1.00 55.37  ? 923  LEU A C   1 
ATOM   2704 O O   . LEU A 1 912  ? 198.224 205.249 219.051 1.00 55.37  ? 923  LEU A O   1 
ATOM   2705 C CB  . LEU A 1 912  ? 198.464 202.980 221.418 1.00 55.37  ? 923  LEU A CB  1 
ATOM   2706 C CG  . LEU A 1 912  ? 199.683 203.869 221.662 1.00 55.37  ? 923  LEU A CG  1 
ATOM   2707 C CD1 . LEU A 1 912  ? 199.264 205.173 222.313 1.00 55.37  ? 923  LEU A CD1 1 
ATOM   2708 C CD2 . LEU A 1 912  ? 200.708 203.144 222.518 1.00 55.37  ? 923  LEU A CD2 1 
ATOM   2709 N N   . ALA A 1 913  ? 198.159 203.147 218.252 1.00 56.15  ? 924  ALA A N   1 
ATOM   2710 C CA  . ALA A 1 913  ? 198.706 203.548 216.961 1.00 56.15  ? 924  ALA A CA  1 
ATOM   2711 C C   . ALA A 1 913  ? 197.710 204.389 216.170 1.00 56.15  ? 924  ALA A C   1 
ATOM   2712 O O   . ALA A 1 913  ? 198.103 205.330 215.471 1.00 56.15  ? 924  ALA A O   1 
ATOM   2713 C CB  . ALA A 1 913  ? 199.121 202.315 216.161 1.00 56.15  ? 924  ALA A CB  1 
ATOM   2714 N N   . PHE A 1 914  ? 196.419 204.068 216.266 1.00 58.35  ? 925  PHE A N   1 
ATOM   2715 C CA  . PHE A 1 914  ? 195.419 204.748 215.448 1.00 58.35  ? 925  PHE A CA  1 
ATOM   2716 C C   . PHE A 1 914  ? 195.022 206.093 216.049 1.00 58.35  ? 925  PHE A C   1 
ATOM   2717 O O   . PHE A 1 914  ? 195.247 207.146 215.443 1.00 58.35  ? 925  PHE A O   1 
ATOM   2718 C CB  . PHE A 1 914  ? 194.190 203.849 215.279 1.00 58.35  ? 925  PHE A CB  1 
ATOM   2719 C CG  . PHE A 1 914  ? 193.386 204.137 214.039 1.00 58.35  ? 925  PHE A CG  1 
ATOM   2720 C CD1 . PHE A 1 914  ? 193.624 205.272 213.282 1.00 58.35  ? 925  PHE A CD1 1 
ATOM   2721 C CD2 . PHE A 1 914  ? 192.387 203.268 213.633 1.00 58.35  ? 925  PHE A CD2 1 
ATOM   2722 C CE1 . PHE A 1 914  ? 192.883 205.534 212.146 1.00 58.35  ? 925  PHE A CE1 1 
ATOM   2723 C CE2 . PHE A 1 914  ? 191.643 203.525 212.499 1.00 58.35  ? 925  PHE A CE2 1 
ATOM   2724 C CZ  . PHE A 1 914  ? 191.891 204.660 211.755 1.00 58.35  ? 925  PHE A CZ  1 
ATOM   2725 N N   . GLY A 1 915  ? 194.432 206.077 217.240 1.00 59.70  ? 926  GLY A N   1 
ATOM   2726 C CA  . GLY A 1 915  ? 193.925 207.298 217.833 1.00 59.70  ? 926  GLY A CA  1 
ATOM   2727 C C   . GLY A 1 915  ? 194.717 207.782 219.028 1.00 59.70  ? 926  GLY A C   1 
ATOM   2728 O O   . GLY A 1 915  ? 194.519 208.906 219.498 1.00 59.70  ? 926  GLY A O   1 
ATOM   2729 N N   . GLY A 1 916  ? 195.617 206.942 219.530 1.00 61.43  ? 927  GLY A N   1 
ATOM   2730 C CA  . GLY A 1 916  ? 196.412 207.300 220.687 1.00 61.43  ? 927  GLY A CA  1 
ATOM   2731 C C   . GLY A 1 916  ? 195.643 207.202 221.986 1.00 61.43  ? 927  GLY A C   1 
ATOM   2732 O O   . GLY A 1 916  ? 194.433 207.448 222.022 1.00 61.43  ? 927  GLY A O   1 
ATOM   2733 N N   . GLN A 1 917  ? 196.333 206.846 223.062 1.00 62.17  ? 928  GLN A N   1 
ATOM   2734 C CA  . GLN A 1 917  ? 195.734 206.715 224.380 1.00 62.17  ? 928  GLN A CA  1 
ATOM   2735 C C   . GLN A 1 917  ? 196.203 207.855 225.276 1.00 62.17  ? 928  GLN A C   1 
ATOM   2736 O O   . GLN A 1 917  ? 197.062 208.661 224.907 1.00 62.17  ? 928  GLN A O   1 
ATOM   2737 C CB  . GLN A 1 917  ? 196.080 205.357 224.996 1.00 62.17  ? 928  GLN A CB  1 
ATOM   2738 C CG  . GLN A 1 917  ? 195.485 204.167 224.267 1.00 62.17  ? 928  GLN A CG  1 
ATOM   2739 C CD  . GLN A 1 917  ? 195.604 202.883 225.063 1.00 62.17  ? 928  GLN A CD  1 
ATOM   2740 O OE1 . GLN A 1 917  ? 195.220 202.826 226.231 1.00 62.17  ? 928  GLN A OE1 1 
ATOM   2741 N NE2 . GLN A 1 917  ? 196.141 201.844 224.435 1.00 62.17  ? 928  GLN A NE2 1 
ATOM   2742 N N   . LYS A 1 918  ? 195.624 207.914 226.470 1.00 66.44  ? 929  LYS A N   1 
ATOM   2743 C CA  . LYS A 1 918  ? 196.009 208.879 227.488 1.00 66.44  ? 929  LYS A CA  1 
ATOM   2744 C C   . LYS A 1 918  ? 196.519 208.135 228.712 1.00 66.44  ? 929  LYS A C   1 
ATOM   2745 O O   . LYS A 1 918  ? 195.924 207.141 229.139 1.00 66.44  ? 929  LYS A O   1 
ATOM   2746 C CB  . LYS A 1 918  ? 194.835 209.782 227.878 1.00 66.44  ? 929  LYS A CB  1 
ATOM   2747 C CG  . LYS A 1 918  ? 194.235 210.561 226.722 1.00 66.44  ? 929  LYS A CG  1 
ATOM   2748 C CD  . LYS A 1 918  ? 193.223 211.582 227.218 1.00 66.44  ? 929  LYS A CD  1 
ATOM   2749 C CE  . LYS A 1 918  ? 193.825 212.481 228.287 1.00 66.44  ? 929  LYS A CE  1 
ATOM   2750 N NZ  . LYS A 1 918  ? 192.882 213.555 228.706 1.00 66.44  ? 929  LYS A NZ  1 
ATOM   2751 N N   . ASP A 1 919  ? 197.624 208.619 229.270 1.00 70.22  ? 930  ASP A N   1 
ATOM   2752 C CA  . ASP A 1 919  ? 198.187 208.002 230.457 1.00 70.22  ? 930  ASP A CA  1 
ATOM   2753 C C   . ASP A 1 919  ? 197.266 208.214 231.654 1.00 70.22  ? 930  ASP A C   1 
ATOM   2754 O O   . ASP A 1 919  ? 196.364 209.057 231.639 1.00 70.22  ? 930  ASP A O   1 
ATOM   2755 C CB  . ASP A 1 919  ? 199.575 208.570 230.749 1.00 70.22  ? 930  ASP A CB  1 
ATOM   2756 C CG  . ASP A 1 919  ? 200.433 207.622 231.563 1.00 70.22  ? 930  ASP A CG  1 
ATOM   2757 O OD1 . ASP A 1 919  ? 201.504 207.215 231.067 1.00 70.22  ? 930  ASP A OD1 1 
ATOM   2758 O OD2 . ASP A 1 919  ? 200.036 207.284 232.697 1.00 70.22  ? 930  ASP A OD2 1 
ATOM   2759 N N   . SER A 1 920  ? 197.497 207.427 232.696 1.00 74.97  ? 931  SER A N   1 
ATOM   2760 C CA  . SER A 1 920  ? 196.673 207.520 233.890 1.00 74.97  ? 931  SER A CA  1 
ATOM   2761 C C   . SER A 1 920  ? 196.821 208.905 234.516 1.00 74.97  ? 931  SER A C   1 
ATOM   2762 O O   . SER A 1 920  ? 197.935 209.444 234.573 1.00 74.97  ? 931  SER A O   1 
ATOM   2763 C CB  . SER A 1 920  ? 197.069 206.437 234.897 1.00 74.97  ? 931  SER A CB  1 
ATOM   2764 O OG  . SER A 1 920  ? 198.365 206.673 235.417 1.00 74.97  ? 931  SER A OG  1 
ATOM   2765 N N   . PRO A 1 921  ? 195.730 209.515 234.983 1.00 76.65  ? 932  PRO A N   1 
ATOM   2766 C CA  . PRO A 1 921  ? 195.841 210.845 235.603 1.00 76.65  ? 932  PRO A CA  1 
ATOM   2767 C C   . PRO A 1 921  ? 196.689 210.857 236.860 1.00 76.65  ? 932  PRO A C   1 
ATOM   2768 O O   . PRO A 1 921  ? 197.173 211.926 237.252 1.00 76.65  ? 932  PRO A O   1 
ATOM   2769 C CB  . PRO A 1 921  ? 194.382 211.214 235.907 1.00 76.65  ? 932  PRO A CB  1 
ATOM   2770 C CG  . PRO A 1 921  ? 193.663 209.902 235.967 1.00 76.65  ? 932  PRO A CG  1 
ATOM   2771 C CD  . PRO A 1 921  ? 194.340 209.032 234.953 1.00 76.65  ? 932  PRO A CD  1 
ATOM   2772 N N   . SER A 1 922  ? 196.881 209.707 237.508 1.00 79.39  ? 933  SER A N   1 
ATOM   2773 C CA  . SER A 1 922  ? 197.689 209.666 238.721 1.00 79.39  ? 933  SER A CA  1 
ATOM   2774 C C   . SER A 1 922  ? 199.161 209.924 238.416 1.00 79.39  ? 933  SER A C   1 
ATOM   2775 O O   . SER A 1 922  ? 199.817 210.713 239.104 1.00 79.39  ? 933  SER A O   1 
ATOM   2776 C CB  . SER A 1 922  ? 197.512 208.319 239.423 1.00 79.39  ? 933  SER A CB  1 
ATOM   2777 O OG  . SER A 1 922  ? 198.048 207.263 238.645 1.00 79.39  ? 933  SER A OG  1 
ATOM   2778 N N   . ASN A 1 923  ? 199.700 209.266 237.388 1.00 75.60  ? 934  ASN A N   1 
ATOM   2779 C CA  . ASN A 1 923  ? 201.137 209.359 237.129 1.00 75.60  ? 934  ASN A CA  1 
ATOM   2780 C C   . ASN A 1 923  ? 201.490 210.614 236.334 1.00 75.60  ? 934  ASN A C   1 
ATOM   2781 O O   . ASN A 1 923  ? 202.144 211.526 236.848 1.00 75.60  ? 934  ASN A O   1 
ATOM   2782 C CB  . ASN A 1 923  ? 201.611 208.103 236.391 1.00 75.60  ? 934  ASN A CB  1 
ATOM   2783 C CG  . ASN A 1 923  ? 201.433 206.842 237.211 1.00 75.60  ? 934  ASN A CG  1 
ATOM   2784 O OD1 . ASN A 1 923  ? 200.407 206.652 237.863 1.00 75.60  ? 934  ASN A OD1 1 
ATOM   2785 N ND2 . ASN A 1 923  ? 202.431 205.968 237.174 1.00 75.60  ? 934  ASN A ND2 1 
ATOM   2786 N N   . THR A 1 924  ? 201.062 210.675 235.074 1.00 72.92  ? 935  THR A N   1 
ATOM   2787 C CA  . THR A 1 924  ? 201.352 211.811 234.206 1.00 72.92  ? 935  THR A CA  1 
ATOM   2788 C C   . THR A 1 924  ? 200.099 212.455 233.636 1.00 72.92  ? 935  THR A C   1 
ATOM   2789 O O   . THR A 1 924  ? 199.969 213.684 233.668 1.00 72.92  ? 935  THR A O   1 
ATOM   2790 C CB  . THR A 1 924  ? 202.287 211.384 233.062 1.00 72.92  ? 935  THR A CB  1 
ATOM   2791 O OG1 . THR A 1 924  ? 201.696 210.300 232.337 1.00 72.92  ? 935  THR A OG1 1 
ATOM   2792 C CG2 . THR A 1 924  ? 203.638 210.947 233.609 1.00 72.92  ? 935  THR A CG2 1 
ATOM   2793 N N   . GLY A 1 925  ? 199.171 211.659 233.113 1.00 71.40  ? 936  GLY A N   1 
ATOM   2794 C CA  . GLY A 1 925  ? 198.012 212.206 232.434 1.00 71.40  ? 936  GLY A CA  1 
ATOM   2795 C C   . GLY A 1 925  ? 198.327 212.925 231.141 1.00 71.40  ? 936  GLY A C   1 
ATOM   2796 O O   . GLY A 1 925  ? 197.793 214.013 230.894 1.00 71.40  ? 936  GLY A O   1 
ATOM   2797 N N   . LYS A 1 926  ? 199.184 212.345 230.303 1.00 69.79  ? 937  LYS A N   1 
ATOM   2798 C CA  . LYS A 1 926  ? 199.592 212.949 229.044 1.00 69.79  ? 937  LYS A CA  1 
ATOM   2799 C C   . LYS A 1 926  ? 199.137 212.085 227.875 1.00 69.79  ? 937  LYS A C   1 
ATOM   2800 O O   . LYS A 1 926  ? 198.994 210.865 228.000 1.00 69.79  ? 937  LYS A O   1 
ATOM   2801 C CB  . LYS A 1 926  ? 201.113 213.138 228.983 1.00 69.79  ? 937  LYS A CB  1 
ATOM   2802 C CG  . LYS A 1 926  ? 201.668 214.064 230.050 1.00 69.79  ? 937  LYS A CG  1 
ATOM   2803 C CD  . LYS A 1 926  ? 203.155 214.304 229.850 1.00 69.79  ? 937  LYS A CD  1 
ATOM   2804 C CE  . LYS A 1 926  ? 203.722 215.191 230.945 1.00 69.79  ? 937  LYS A CE  1 
ATOM   2805 N NZ  . LYS A 1 926  ? 202.963 216.465 231.076 1.00 69.79  ? 937  LYS A NZ  1 
ATOM   2806 N N   . LYS A 1 927  ? 198.926 212.755 226.742 1.00 64.60  ? 938  LYS A N   1 
ATOM   2807 C CA  . LYS A 1 927  ? 198.472 212.041 225.529 1.00 64.60  ? 938  LYS A CA  1 
ATOM   2808 C C   . LYS A 1 927  ? 199.680 211.699 224.663 1.00 64.60  ? 938  LYS A C   1 
ATOM   2809 O O   . LYS A 1 927  ? 200.597 212.536 224.565 1.00 64.60  ? 938  LYS A O   1 
ATOM   2810 C CB  . LYS A 1 927  ? 197.538 212.902 224.673 1.00 64.60  ? 938  LYS A CB  1 
ATOM   2811 C CG  . LYS A 1 927  ? 196.185 213.242 225.276 1.00 64.60  ? 938  LYS A CG  1 
ATOM   2812 C CD  . LYS A 1 927  ? 195.273 213.925 224.265 1.00 64.60  ? 938  LYS A CD  1 
ATOM   2813 C CE  . LYS A 1 927  ? 193.925 214.251 224.822 1.00 64.60  ? 938  LYS A CE  1 
ATOM   2814 N NZ  . LYS A 1 927  ? 194.026 215.122 225.995 1.00 64.60  ? 938  LYS A NZ  1 
ATOM   2815 N N   . TRP A 1 928  ? 199.675 210.510 224.078 1.00 58.43  ? 939  TRP A N   1 
ATOM   2816 C CA  . TRP A 1 928  ? 200.724 210.095 223.160 1.00 58.43  ? 939  TRP A CA  1 
ATOM   2817 C C   . TRP A 1 928  ? 200.150 209.079 222.184 1.00 58.43  ? 939  TRP A C   1 
ATOM   2818 O O   . TRP A 1 928  ? 199.110 208.465 222.435 1.00 58.43  ? 939  TRP A O   1 
ATOM   2819 C CB  . TRP A 1 928  ? 201.934 209.513 223.903 1.00 58.43  ? 939  TRP A CB  1 
ATOM   2820 C CG  . TRP A 1 928  ? 201.839 208.042 224.170 1.00 58.43  ? 939  TRP A CG  1 
ATOM   2821 C CD1 . TRP A 1 928  ? 202.447 207.042 223.469 1.00 58.43  ? 939  TRP A CD1 1 
ATOM   2822 C CD2 . TRP A 1 928  ? 201.102 207.404 225.220 1.00 58.43  ? 939  TRP A CD2 1 
ATOM   2823 N NE1 . TRP A 1 928  ? 202.130 205.822 224.013 1.00 58.43  ? 939  TRP A NE1 1 
ATOM   2824 C CE2 . TRP A 1 928  ? 201.306 206.017 225.089 1.00 58.43  ? 939  TRP A CE2 1 
ATOM   2825 C CE3 . TRP A 1 928  ? 200.288 207.872 226.256 1.00 58.43  ? 939  TRP A CE3 1 
ATOM   2826 C CZ2 . TRP A 1 928  ? 200.726 205.093 225.954 1.00 58.43  ? 939  TRP A CZ2 1 
ATOM   2827 C CZ3 . TRP A 1 928  ? 199.713 206.952 227.113 1.00 58.43  ? 939  TRP A CZ3 1 
ATOM   2828 C CH2 . TRP A 1 928  ? 199.935 205.579 226.958 1.00 58.43  ? 939  TRP A CH2 1 
ATOM   2829 N N   . GLY A 1 929  ? 200.842 208.912 221.059 1.00 56.69  ? 940  GLY A N   1 
ATOM   2830 C CA  . GLY A 1 929  ? 200.403 207.984 220.036 1.00 56.69  ? 940  GLY A CA  1 
ATOM   2831 C C   . GLY A 1 929  ? 200.026 208.662 218.735 1.00 56.69  ? 940  GLY A C   1 
ATOM   2832 O O   . GLY A 1 929  ? 200.559 209.725 218.404 1.00 56.69  ? 940  GLY A O   1 
ATOM   2833 N N   . GLY A 1 930  ? 199.104 208.057 217.989 1.00 55.70  ? 941  GLY A N   1 
ATOM   2834 C CA  . GLY A 1 930  ? 198.676 208.609 216.719 1.00 55.70  ? 941  GLY A CA  1 
ATOM   2835 C C   . GLY A 1 930  ? 199.758 208.572 215.660 1.00 55.70  ? 941  GLY A C   1 
ATOM   2836 O O   . GLY A 1 930  ? 200.160 209.615 215.136 1.00 55.70  ? 941  GLY A O   1 
ATOM   2837 N N   . VAL A 1 931  ? 200.236 207.375 215.336 1.00 52.12  ? 942  VAL A N   1 
ATOM   2838 C CA  . VAL A 1 931  ? 201.320 207.217 214.374 1.00 52.12  ? 942  VAL A CA  1 
ATOM   2839 C C   . VAL A 1 931  ? 200.772 207.393 212.964 1.00 52.12  ? 942  VAL A C   1 
ATOM   2840 O O   . VAL A 1 931  ? 199.779 206.761 212.585 1.00 52.12  ? 942  VAL A O   1 
ATOM   2841 C CB  . VAL A 1 931  ? 201.996 205.847 214.538 1.00 52.12  ? 942  VAL A CB  1 
ATOM   2842 C CG1 . VAL A 1 931  ? 203.250 205.770 213.683 1.00 52.12  ? 942  VAL A CG1 1 
ATOM   2843 C CG2 . VAL A 1 931  ? 202.323 205.590 216.000 1.00 52.12  ? 942  VAL A CG2 1 
ATOM   2844 N N   . ARG A 1 932  ? 201.420 208.255 212.184 1.00 53.36  ? 943  ARG A N   1 
ATOM   2845 C CA  . ARG A 1 932  ? 201.061 208.495 210.793 1.00 53.36  ? 943  ARG A CA  1 
ATOM   2846 C C   . ARG A 1 932  ? 202.279 208.243 209.918 1.00 53.36  ? 943  ARG A C   1 
ATOM   2847 O O   . ARG A 1 932  ? 203.374 208.731 210.217 1.00 53.36  ? 943  ARG A O   1 
ATOM   2848 C CB  . ARG A 1 932  ? 200.548 209.924 210.592 1.00 53.36  ? 943  ARG A CB  1 
ATOM   2849 C CG  . ARG A 1 932  ? 199.462 210.339 211.569 1.00 53.36  ? 943  ARG A CG  1 
ATOM   2850 C CD  . ARG A 1 932  ? 198.149 209.639 211.265 1.00 53.36  ? 943  ARG A CD  1 
ATOM   2851 N NE  . ARG A 1 932  ? 197.140 209.903 212.284 1.00 53.36  ? 943  ARG A NE  1 
ATOM   2852 C CZ  . ARG A 1 932  ? 196.850 209.078 213.281 1.00 53.36  ? 943  ARG A CZ  1 
ATOM   2853 N NH1 . ARG A 1 932  ? 197.477 207.923 213.428 1.00 53.36  ? 943  ARG A NH1 1 
ATOM   2854 N NH2 . ARG A 1 932  ? 195.905 209.422 214.153 1.00 53.36  ? 943  ARG A NH2 1 
ATOM   2855 N N   . ALA A 1 933  ? 202.087 207.487 208.840 1.00 52.35  ? 944  ALA A N   1 
ATOM   2856 C CA  . ALA A 1 933  ? 203.170 207.090 207.946 1.00 52.35  ? 944  ALA A CA  1 
ATOM   2857 C C   . ALA A 1 933  ? 203.049 207.873 206.644 1.00 52.35  ? 944  ALA A C   1 
ATOM   2858 O O   . ALA A 1 933  ? 202.068 207.718 205.909 1.00 52.35  ? 944  ALA A O   1 
ATOM   2859 C CB  . ALA A 1 933  ? 203.135 205.586 207.684 1.00 52.35  ? 944  ALA A CB  1 
ATOM   2860 N N   . ASP A 1 934  ? 204.046 208.708 206.361 1.00 54.80  ? 945  ASP A N   1 
ATOM   2861 C CA  . ASP A 1 934  ? 204.129 209.457 205.112 1.00 54.80  ? 945  ASP A CA  1 
ATOM   2862 C C   . ASP A 1 934  ? 205.333 208.945 204.331 1.00 54.80  ? 945  ASP A C   1 
ATOM   2863 O O   . ASP A 1 934  ? 206.477 209.097 204.773 1.00 54.80  ? 945  ASP A O   1 
ATOM   2864 C CB  . ASP A 1 934  ? 204.236 210.959 205.373 1.00 54.80  ? 945  ASP A CB  1 
ATOM   2865 C CG  . ASP A 1 934  ? 205.103 211.283 206.570 1.00 54.80  ? 945  ASP A CG  1 
ATOM   2866 O OD1 . ASP A 1 934  ? 205.656 210.344 207.175 1.00 54.80  ? 945  ASP A OD1 1 
ATOM   2867 O OD2 . ASP A 1 934  ? 205.231 212.479 206.907 1.00 54.80  ? 945  ASP A OD2 1 
ATOM   2868 N N   . GLY A 1 935  ? 205.076 208.339 203.174 1.00 53.21  ? 946  GLY A N   1 
ATOM   2869 C CA  . GLY A 1 935  ? 206.134 207.784 202.358 1.00 53.21  ? 946  GLY A CA  1 
ATOM   2870 C C   . GLY A 1 935  ? 205.664 207.558 200.938 1.00 53.21  ? 946  GLY A C   1 
ATOM   2871 O O   . GLY A 1 935  ? 204.524 207.858 200.581 1.00 53.21  ? 946  GLY A O   1 
ATOM   2872 N N   . VAL A 1 936  ? 206.568 207.016 200.124 1.00 51.25  ? 947  VAL A N   1 
ATOM   2873 C CA  . VAL A 1 936  ? 206.299 206.737 198.721 1.00 51.25  ? 947  VAL A CA  1 
ATOM   2874 C C   . VAL A 1 936  ? 206.575 205.263 198.457 1.00 51.25  ? 947  VAL A C   1 
ATOM   2875 O O   . VAL A 1 936  ? 207.295 204.595 199.202 1.00 51.25  ? 947  VAL A O   1 
ATOM   2876 C CB  . VAL A 1 936  ? 207.138 207.623 197.779 1.00 51.25  ? 947  VAL A CB  1 
ATOM   2877 C CG1 . VAL A 1 936  ? 206.809 209.092 197.997 1.00 51.25  ? 947  VAL A CG1 1 
ATOM   2878 C CG2 . VAL A 1 936  ? 208.622 207.366 197.990 1.00 51.25  ? 947  VAL A CG2 1 
ATOM   2879 N N   . GLY A 1 937  ? 205.988 204.761 197.382 1.00 51.23  ? 948  GLY A N   1 
ATOM   2880 C CA  . GLY A 1 937  ? 206.143 203.361 197.024 1.00 51.23  ? 948  GLY A CA  1 
ATOM   2881 C C   . GLY A 1 937  ? 206.184 203.183 195.526 1.00 51.23  ? 948  GLY A C   1 
ATOM   2882 O O   . GLY A 1 937  ? 205.611 203.974 194.770 1.00 51.23  ? 948  GLY A O   1 
ATOM   2883 N N   . LEU A 1 938  ? 206.876 202.131 195.093 1.00 53.11  ? 949  LEU A N   1 
ATOM   2884 C CA  . LEU A 1 938  ? 206.984 201.779 193.685 1.00 53.11  ? 949  LEU A CA  1 
ATOM   2885 C C   . LEU A 1 938  ? 206.582 200.323 193.512 1.00 53.11  ? 949  LEU A C   1 
ATOM   2886 O O   . LEU A 1 938  ? 207.131 199.442 194.183 1.00 53.11  ? 949  LEU A O   1 
ATOM   2887 C CB  . LEU A 1 938  ? 208.407 202.008 193.165 1.00 53.11  ? 949  LEU A CB  1 
ATOM   2888 C CG  . LEU A 1 938  ? 208.743 201.410 191.798 1.00 53.11  ? 949  LEU A CG  1 
ATOM   2889 C CD1 . LEU A 1 938  ? 207.914 202.062 190.704 1.00 53.11  ? 949  LEU A CD1 1 
ATOM   2890 C CD2 . LEU A 1 938  ? 210.229 201.548 191.503 1.00 53.11  ? 949  LEU A CD2 1 
ATOM   2891 N N   . SER A 1 939  ? 205.630 200.072 192.618 1.00 57.77  ? 950  SER A N   1 
ATOM   2892 C CA  . SER A 1 939  ? 205.099 198.736 192.385 1.00 57.77  ? 950  SER A CA  1 
ATOM   2893 C C   . SER A 1 939  ? 205.272 198.367 190.920 1.00 57.77  ? 950  SER A C   1 
ATOM   2894 O O   . SER A 1 939  ? 204.962 199.170 190.034 1.00 57.77  ? 950  SER A O   1 
ATOM   2895 C CB  . SER A 1 939  ? 203.623 198.654 192.781 1.00 57.77  ? 950  SER A CB  1 
ATOM   2896 O OG  . SER A 1 939  ? 203.457 198.856 194.174 1.00 57.77  ? 950  SER A OG  1 
ATOM   2897 N N   . LEU A 1 940  ? 205.764 197.156 190.670 1.00 62.18  ? 951  LEU A N   1 
ATOM   2898 C CA  . LEU A 1 940  ? 205.941 196.632 189.323 1.00 62.18  ? 951  LEU A CA  1 
ATOM   2899 C C   . LEU A 1 940  ? 205.047 195.415 189.144 1.00 62.18  ? 951  LEU A C   1 
ATOM   2900 O O   . LEU A 1 940  ? 205.041 194.516 189.991 1.00 62.18  ? 951  LEU A O   1 
ATOM   2901 C CB  . LEU A 1 940  ? 207.402 196.255 189.049 1.00 62.18  ? 951  LEU A CB  1 
ATOM   2902 C CG  . LEU A 1 940  ? 208.442 197.357 188.806 1.00 62.18  ? 951  LEU A CG  1 
ATOM   2903 C CD1 . LEU A 1 940  ? 208.041 198.229 187.622 1.00 62.18  ? 951  LEU A CD1 1 
ATOM   2904 C CD2 . LEU A 1 940  ? 208.703 198.201 190.047 1.00 62.18  ? 951  LEU A CD2 1 
ATOM   2905 N N   . SER A 1 941  ? 204.297 195.388 188.046 1.00 75.78  ? 952  SER A N   1 
ATOM   2906 C CA  . SER A 1 941  ? 203.401 194.284 187.741 1.00 75.78  ? 952  SER A CA  1 
ATOM   2907 C C   . SER A 1 941  ? 203.617 193.830 186.305 1.00 75.78  ? 952  SER A C   1 
ATOM   2908 O O   . SER A 1 941  ? 203.940 194.632 185.424 1.00 75.78  ? 952  SER A O   1 
ATOM   2909 C CB  . SER A 1 941  ? 201.932 194.676 187.950 1.00 75.78  ? 952  SER A CB  1 
ATOM   2910 O OG  . SER A 1 941  ? 201.531 195.668 187.021 1.00 75.78  ? 952  SER A OG  1 
ATOM   2911 N N   . TYR A 1 942  ? 203.433 192.532 186.080 1.00 84.63  ? 953  TYR A N   1 
ATOM   2912 C CA  . TYR A 1 942  ? 203.594 191.945 184.754 1.00 84.63  ? 953  TYR A CA  1 
ATOM   2913 C C   . TYR A 1 942  ? 202.647 190.762 184.640 1.00 84.63  ? 953  TYR A C   1 
ATOM   2914 O O   . TYR A 1 942  ? 202.805 189.771 185.359 1.00 84.63  ? 953  TYR A O   1 
ATOM   2915 C CB  . TYR A 1 942  ? 205.042 191.510 184.516 1.00 84.63  ? 953  TYR A CB  1 
ATOM   2916 C CG  . TYR A 1 942  ? 205.197 190.324 183.590 1.00 84.63  ? 953  TYR A CG  1 
ATOM   2917 C CD1 . TYR A 1 942  ? 204.960 190.446 182.227 1.00 84.63  ? 953  TYR A CD1 1 
ATOM   2918 C CD2 . TYR A 1 942  ? 205.589 189.085 184.079 1.00 84.63  ? 953  TYR A CD2 1 
ATOM   2919 C CE1 . TYR A 1 942  ? 205.104 189.365 181.378 1.00 84.63  ? 953  TYR A CE1 1 
ATOM   2920 C CE2 . TYR A 1 942  ? 205.734 187.999 183.238 1.00 84.63  ? 953  TYR A CE2 1 
ATOM   2921 C CZ  . TYR A 1 942  ? 205.491 188.144 181.890 1.00 84.63  ? 953  TYR A CZ  1 
ATOM   2922 O OH  . TYR A 1 942  ? 205.636 187.064 181.051 1.00 84.63  ? 953  TYR A OH  1 
ATOM   2923 N N   . ASP A 1 943  ? 201.663 190.870 183.751 1.00 91.89  ? 954  ASP A N   1 
ATOM   2924 C CA  . ASP A 1 943  ? 200.681 189.802 183.579 1.00 91.89  ? 954  ASP A CA  1 
ATOM   2925 C C   . ASP A 1 943  ? 200.018 189.949 182.221 1.00 91.89  ? 954  ASP A C   1 
ATOM   2926 O O   . ASP A 1 943  ? 199.268 190.905 181.999 1.00 91.89  ? 954  ASP A O   1 
ATOM   2927 C CB  . ASP A 1 943  ? 199.636 189.839 184.694 1.00 91.89  ? 954  ASP A CB  1 
ATOM   2928 C CG  . ASP A 1 943  ? 198.908 188.520 184.853 1.00 91.89  ? 954  ASP A CG  1 
ATOM   2929 O OD1 . ASP A 1 943  ? 199.426 187.493 184.367 1.00 91.89  ? 954  ASP A OD1 1 
ATOM   2930 O OD2 . ASP A 1 943  ? 197.818 188.510 185.462 1.00 91.89  ? 954  ASP A OD2 1 
ATOM   2931 N N   . LYS A 1 944  ? 200.290 189.008 181.317 1.00 95.63  ? 955  LYS A N   1 
ATOM   2932 C CA  . LYS A 1 944  ? 199.533 188.898 180.079 1.00 95.63  ? 955  LYS A CA  1 
ATOM   2933 C C   . LYS A 1 944  ? 198.404 187.881 180.170 1.00 95.63  ? 955  LYS A C   1 
ATOM   2934 O O   . LYS A 1 944  ? 197.418 188.006 179.436 1.00 95.63  ? 955  LYS A O   1 
ATOM   2935 C CB  . LYS A 1 944  ? 200.465 188.548 178.911 1.00 95.63  ? 955  LYS A CB  1 
ATOM   2936 C CG  . LYS A 1 944  ? 201.371 187.358 179.161 1.00 95.63  ? 955  LYS A CG  1 
ATOM   2937 C CD  . LYS A 1 944  ? 202.717 187.546 178.479 1.00 95.63  ? 955  LYS A CD  1 
ATOM   2938 C CE  . LYS A 1 944  ? 203.609 186.329 178.659 1.00 95.63  ? 955  LYS A CE  1 
ATOM   2939 N NZ  . LYS A 1 944  ? 203.583 185.826 180.061 1.00 95.63  ? 955  LYS A NZ  1 
ATOM   2940 N N   . GLY A 1 945  ? 198.525 186.889 181.047 1.00 96.68  ? 956  GLY A N   1 
ATOM   2941 C CA  . GLY A 1 945  ? 197.372 186.112 181.463 1.00 96.68  ? 956  GLY A CA  1 
ATOM   2942 C C   . GLY A 1 945  ? 197.102 184.821 180.722 1.00 96.68  ? 956  GLY A C   1 
ATOM   2943 O O   . GLY A 1 945  ? 195.955 184.569 180.334 1.00 96.68  ? 956  GLY A O   1 
ATOM   2944 N N   . GLU A 1 946  ? 198.122 183.988 180.508 1.00 95.67  ? 957  GLU A N   1 
ATOM   2945 C CA  . GLU A 1 946  ? 197.890 182.641 179.995 1.00 95.67  ? 957  GLU A CA  1 
ATOM   2946 C C   . GLU A 1 946  ? 198.326 181.565 180.989 1.00 95.67  ? 957  GLU A C   1 
ATOM   2947 O O   . GLU A 1 946  ? 197.517 180.714 181.371 1.00 95.67  ? 957  GLU A O   1 
ATOM   2948 C CB  . GLU A 1 946  ? 198.571 182.461 178.624 1.00 95.67  ? 957  GLU A CB  1 
ATOM   2949 C CG  . GLU A 1 946  ? 200.096 182.474 178.593 1.00 95.67  ? 957  GLU A CG  1 
ATOM   2950 C CD  . GLU A 1 946  ? 200.676 183.860 178.762 1.00 95.67  ? 957  GLU A CD  1 
ATOM   2951 O OE1 . GLU A 1 946  ? 200.539 184.430 179.864 1.00 95.67  ? 957  GLU A OE1 1 
ATOM   2952 O OE2 . GLU A 1 946  ? 201.259 184.381 177.788 1.00 95.67  ? 957  GLU A OE2 1 
ATOM   2953 N N   . ALA A 1 947  ? 199.596 181.583 181.423 1.00 90.13  ? 958  ALA A N   1 
ATOM   2954 C CA  . ALA A 1 947  ? 200.073 180.574 182.364 1.00 90.13  ? 958  ALA A CA  1 
ATOM   2955 C C   . ALA A 1 947  ? 201.093 181.128 183.355 1.00 90.13  ? 958  ALA A C   1 
ATOM   2956 O O   . ALA A 1 947  ? 201.877 180.357 183.919 1.00 90.13  ? 958  ALA A O   1 
ATOM   2957 C CB  . ALA A 1 947  ? 200.683 179.381 181.619 1.00 90.13  ? 958  ALA A CB  1 
ATOM   2958 N N   . ASN A 1 948  ? 201.108 182.439 183.580 1.00 88.26  ? 959  ASN A N   1 
ATOM   2959 C CA  . ASN A 1 948  ? 202.135 183.024 184.434 1.00 88.26  ? 959  ASN A CA  1 
ATOM   2960 C C   . ASN A 1 948  ? 201.657 184.368 184.963 1.00 88.26  ? 959  ASN A C   1 
ATOM   2961 O O   . ASN A 1 948  ? 200.685 184.947 184.472 1.00 88.26  ? 959  ASN A O   1 
ATOM   2962 C CB  . ASN A 1 948  ? 203.461 183.178 183.681 1.00 88.26  ? 959  ASN A CB  1 
ATOM   2963 C CG  . ASN A 1 948  ? 204.476 182.122 184.069 1.00 88.26  ? 959  ASN A CG  1 
ATOM   2964 O OD1 . ASN A 1 948  ? 204.361 181.489 185.118 1.00 88.26  ? 959  ASN A OD1 1 
ATOM   2965 N ND2 . ASN A 1 948  ? 205.480 181.927 183.221 1.00 88.26  ? 959  ASN A ND2 1 
ATOM   2966 N N   . GLY A 1 949  ? 202.362 184.853 185.983 1.00 78.99  ? 960  GLY A N   1 
ATOM   2967 C CA  . GLY A 1 949  ? 202.108 186.157 186.565 1.00 78.99  ? 960  GLY A CA  1 
ATOM   2968 C C   . GLY A 1 949  ? 203.129 186.512 187.626 1.00 78.99  ? 960  GLY A C   1 
ATOM   2969 O O   . GLY A 1 949  ? 203.416 185.703 188.512 1.00 78.99  ? 960  GLY A O   1 
ATOM   2970 N N   . VAL A 1 950  ? 203.686 187.719 187.549 1.00 73.30  ? 961  VAL A N   1 
ATOM   2971 C CA  . VAL A 1 950  ? 204.738 188.150 188.464 1.00 73.30  ? 961  VAL A CA  1 
ATOM   2972 C C   . VAL A 1 950  ? 204.469 189.593 188.866 1.00 73.30  ? 961  VAL A C   1 
ATOM   2973 O O   . VAL A 1 950  ? 204.158 190.438 188.021 1.00 73.30  ? 961  VAL A O   1 
ATOM   2974 C CB  . VAL A 1 950  ? 206.136 187.992 187.824 1.00 73.30  ? 961  VAL A CB  1 
ATOM   2975 C CG1 . VAL A 1 950  ? 207.140 188.938 188.468 1.00 73.30  ? 961  VAL A CG1 1 
ATOM   2976 C CG2 . VAL A 1 950  ? 206.611 186.551 187.934 1.00 73.30  ? 961  VAL A CG2 1 
ATOM   2977 N N   . TRP A 1 951  ? 204.589 189.874 190.163 1.00 65.16  ? 962  TRP A N   1 
ATOM   2978 C CA  . TRP A 1 951  ? 204.406 191.223 190.675 1.00 65.16  ? 962  TRP A CA  1 
ATOM   2979 C C   . TRP A 1 951  ? 205.441 191.492 191.758 1.00 65.16  ? 962  TRP A C   1 
ATOM   2980 O O   . TRP A 1 951  ? 205.946 190.567 192.399 1.00 65.16  ? 962  TRP A O   1 
ATOM   2981 C CB  . TRP A 1 951  ? 202.993 191.431 191.230 1.00 65.16  ? 962  TRP A CB  1 
ATOM   2982 C CG  . TRP A 1 951  ? 202.805 190.885 192.611 1.00 65.16  ? 962  TRP A CG  1 
ATOM   2983 C CD1 . TRP A 1 951  ? 202.907 189.581 192.997 1.00 65.16  ? 962  TRP A CD1 1 
ATOM   2984 C CD2 . TRP A 1 951  ? 202.486 191.630 193.792 1.00 65.16  ? 962  TRP A CD2 1 
ATOM   2985 N NE1 . TRP A 1 951  ? 202.669 189.466 194.345 1.00 65.16  ? 962  TRP A NE1 1 
ATOM   2986 C CE2 . TRP A 1 951  ? 202.409 190.710 194.857 1.00 65.16  ? 962  TRP A CE2 1 
ATOM   2987 C CE3 . TRP A 1 951  ? 202.258 192.984 194.053 1.00 65.16  ? 962  TRP A CE3 1 
ATOM   2988 C CZ2 . TRP A 1 951  ? 202.113 191.101 196.161 1.00 65.16  ? 962  TRP A CZ2 1 
ATOM   2989 C CZ3 . TRP A 1 951  ? 201.964 193.370 195.349 1.00 65.16  ? 962  TRP A CZ3 1 
ATOM   2990 C CH2 . TRP A 1 951  ? 201.894 192.432 196.386 1.00 65.16  ? 962  TRP A CH2 1 
ATOM   2991 N N   . ALA A 1 952  ? 205.749 192.773 191.955 1.00 60.44  ? 963  ALA A N   1 
ATOM   2992 C CA  . ALA A 1 952  ? 206.705 193.189 192.970 1.00 60.44  ? 963  ALA A CA  1 
ATOM   2993 C C   . ALA A 1 952  ? 206.340 194.585 193.450 1.00 60.44  ? 963  ALA A C   1 
ATOM   2994 O O   . ALA A 1 952  ? 205.636 195.333 192.766 1.00 60.44  ? 963  ALA A O   1 
ATOM   2995 C CB  . ALA A 1 952  ? 208.143 193.160 192.440 1.00 60.44  ? 963  ALA A CB  1 
ATOM   2996 N N   . SER A 1 953  ? 206.827 194.931 194.640 1.00 55.13  ? 964  SER A N   1 
ATOM   2997 C CA  . SER A 1 953  ? 206.522 196.225 195.232 1.00 55.13  ? 964  SER A CA  1 
ATOM   2998 C C   . SER A 1 953  ? 207.604 196.590 196.238 1.00 55.13  ? 964  SER A C   1 
ATOM   2999 O O   . SER A 1 953  ? 208.162 195.714 196.902 1.00 55.13  ? 964  SER A O   1 
ATOM   3000 C CB  . SER A 1 953  ? 205.148 196.215 195.911 1.00 55.13  ? 964  SER A CB  1 
ATOM   3001 O OG  . SER A 1 953  ? 204.764 197.522 196.303 1.00 55.13  ? 964  SER A OG  1 
ATOM   3002 N N   . LEU A 1 954  ? 207.891 197.886 196.340 1.00 49.79  ? 965  LEU A N   1 
ATOM   3003 C CA  . LEU A 1 954  ? 208.841 198.413 197.309 1.00 49.79  ? 965  LEU A CA  1 
ATOM   3004 C C   . LEU A 1 954  ? 208.339 199.762 197.799 1.00 49.79  ? 965  LEU A C   1 
ATOM   3005 O O   . LEU A 1 954  ? 207.887 200.588 197.002 1.00 49.79  ? 965  LEU A O   1 
ATOM   3006 C CB  . LEU A 1 954  ? 210.245 198.548 196.699 1.00 49.79  ? 965  LEU A CB  1 
ATOM   3007 C CG  . LEU A 1 954  ? 211.318 199.289 197.501 1.00 49.79  ? 965  LEU A CG  1 
ATOM   3008 C CD1 . LEU A 1 954  ? 212.645 198.556 197.405 1.00 49.79  ? 965  LEU A CD1 1 
ATOM   3009 C CD2 . LEU A 1 954  ? 211.472 200.724 197.015 1.00 49.79  ? 965  LEU A CD2 1 
ATOM   3010 N N   . SER A 1 955  ? 208.421 199.983 199.110 1.00 47.96  ? 966  SER A N   1 
ATOM   3011 C CA  . SER A 1 955  ? 207.930 201.220 199.699 1.00 47.96  ? 966  SER A CA  1 
ATOM   3012 C C   . SER A 1 955  ? 208.777 201.587 200.908 1.00 47.96  ? 966  SER A C   1 
ATOM   3013 O O   . SER A 1 955  ? 209.341 200.718 201.578 1.00 47.96  ? 966  SER A O   1 
ATOM   3014 C CB  . SER A 1 955  ? 206.457 201.101 200.106 1.00 47.96  ? 966  SER A CB  1 
ATOM   3015 O OG  . SER A 1 955  ? 206.087 202.148 200.987 1.00 47.96  ? 966  SER A OG  1 
ATOM   3016 N N   . GLY A 1 956  ? 208.858 202.888 201.178 1.00 49.69  ? 967  GLY A N   1 
ATOM   3017 C CA  . GLY A 1 956  ? 209.543 203.387 202.354 1.00 49.69  ? 967  GLY A CA  1 
ATOM   3018 C C   . GLY A 1 956  ? 208.812 204.548 202.996 1.00 49.69  ? 967  GLY A C   1 
ATOM   3019 O O   . GLY A 1 956  ? 208.567 205.568 202.345 1.00 49.69  ? 967  GLY A O   1 
ATOM   3020 N N   . ASP A 1 957  ? 208.458 204.409 204.269 1.00 51.48  ? 968  ASP A N   1 
ATOM   3021 C CA  . ASP A 1 957  ? 207.688 205.408 204.996 1.00 51.48  ? 968  ASP A CA  1 
ATOM   3022 C C   . ASP A 1 957  ? 208.558 206.080 206.054 1.00 51.48  ? 968  ASP A C   1 
ATOM   3023 O O   . ASP A 1 957  ? 209.717 205.714 206.272 1.00 51.48  ? 968  ASP A O   1 
ATOM   3024 C CB  . ASP A 1 957  ? 206.448 204.776 205.635 1.00 51.48  ? 968  ASP A CB  1 
ATOM   3025 C CG  . ASP A 1 957  ? 205.710 203.841 204.693 1.00 51.48  ? 968  ASP A CG  1 
ATOM   3026 O OD1 . ASP A 1 957  ? 206.012 203.843 203.482 1.00 51.48  ? 968  ASP A OD1 1 
ATOM   3027 O OD2 . ASP A 1 957  ? 204.822 203.102 205.166 1.00 51.48  ? 968  ASP A OD2 1 
ATOM   3028 N N   . GLN A 1 958  ? 207.979 207.082 206.717 1.00 50.53  ? 969  GLN A N   1 
ATOM   3029 C CA  . GLN A 1 958  ? 208.623 207.814 207.810 1.00 50.53  ? 969  GLN A CA  1 
ATOM   3030 C C   . GLN A 1 958  ? 207.633 207.853 208.970 1.00 50.53  ? 969  GLN A C   1 
ATOM   3031 O O   . GLN A 1 958  ? 206.828 208.781 209.080 1.00 50.53  ? 969  GLN A O   1 
ATOM   3032 C CB  . GLN A 1 958  ? 209.037 209.214 207.368 1.00 50.53  ? 969  GLN A CB  1 
ATOM   3033 C CG  . GLN A 1 958  ? 210.123 209.842 208.226 1.00 50.53  ? 969  GLN A CG  1 
ATOM   3034 C CD  . GLN A 1 958  ? 211.519 209.466 207.770 1.00 50.53  ? 969  GLN A CD  1 
ATOM   3035 O OE1 . GLN A 1 958  ? 211.700 208.525 206.997 1.00 50.53  ? 969  GLN A OE1 1 
ATOM   3036 N NE2 . GLN A 1 958  ? 212.515 210.201 208.249 1.00 50.53  ? 969  GLN A NE2 1 
ATOM   3037 N N   . LEU A 1 959  ? 207.697 206.848 209.840 1.00 49.04  ? 970  LEU A N   1 
ATOM   3038 C CA  . LEU A 1 959  ? 206.707 206.702 210.900 1.00 49.04  ? 970  LEU A CA  1 
ATOM   3039 C C   . LEU A 1 959  ? 206.894 207.789 211.952 1.00 49.04  ? 970  LEU A C   1 
ATOM   3040 O O   . LEU A 1 959  ? 207.920 207.831 212.639 1.00 49.04  ? 970  LEU A O   1 
ATOM   3041 C CB  . LEU A 1 959  ? 206.803 205.317 211.538 1.00 49.04  ? 970  LEU A CB  1 
ATOM   3042 C CG  . LEU A 1 959  ? 206.299 204.082 210.777 1.00 49.04  ? 970  LEU A CG  1 
ATOM   3043 C CD1 . LEU A 1 959  ? 204.785 204.127 210.654 1.00 49.04  ? 970  LEU A CD1 1 
ATOM   3044 C CD2 . LEU A 1 959  ? 206.948 203.888 209.411 1.00 49.04  ? 970  LEU A CD2 1 
ATOM   3045 N N   . THR A 1 960  ? 205.897 208.662 212.082 1.00 52.37  ? 971  THR A N   1 
ATOM   3046 C CA  . THR A 1 960  ? 205.919 209.741 213.058 1.00 52.37  ? 971  THR A CA  1 
ATOM   3047 C C   . THR A 1 960  ? 204.554 209.835 213.724 1.00 52.37  ? 971  THR A C   1 
ATOM   3048 O O   . THR A 1 960  ? 203.549 209.349 213.199 1.00 52.37  ? 971  THR A O   1 
ATOM   3049 C CB  . THR A 1 960  ? 206.281 211.088 212.417 1.00 52.37  ? 971  THR A CB  1 
ATOM   3050 O OG1 . THR A 1 960  ? 205.473 211.297 211.252 1.00 52.37  ? 971  THR A OG1 1 
ATOM   3051 C CG2 . THR A 1 960  ? 207.750 211.122 212.026 1.00 52.37  ? 971  THR A CG2 1 
ATOM   3052 N N   . GLY A 1 961  ? 204.528 210.469 214.890 1.00 55.28  ? 972  GLY A N   1 
ATOM   3053 C CA  . GLY A 1 961  ? 203.285 210.610 215.625 1.00 55.28  ? 972  GLY A CA  1 
ATOM   3054 C C   . GLY A 1 961  ? 203.441 211.596 216.759 1.00 55.28  ? 972  GLY A C   1 
ATOM   3055 O O   . GLY A 1 961  ? 204.495 212.212 216.942 1.00 55.28  ? 972  GLY A O   1 
ATOM   3056 N N   . LYS A 1 962  ? 202.363 211.738 217.527 1.00 57.77  ? 973  LYS A N   1 
ATOM   3057 C CA  . LYS A 1 962  ? 202.328 212.681 218.638 1.00 57.77  ? 973  LYS A CA  1 
ATOM   3058 C C   . LYS A 1 962  ? 203.004 212.068 219.858 1.00 57.77  ? 973  LYS A C   1 
ATOM   3059 O O   . LYS A 1 962  ? 202.601 210.995 220.323 1.00 57.77  ? 973  LYS A O   1 
ATOM   3060 C CB  . LYS A 1 962  ? 200.886 213.068 218.957 1.00 57.77  ? 973  LYS A CB  1 
ATOM   3061 C CG  . LYS A 1 962  ? 200.731 213.944 220.188 1.00 57.77  ? 973  LYS A CG  1 
ATOM   3062 C CD  . LYS A 1 962  ? 201.490 215.250 220.039 1.00 57.77  ? 973  LYS A CD  1 
ATOM   3063 C CE  . LYS A 1 962  ? 201.298 216.137 221.258 1.00 57.77  ? 973  LYS A CE  1 
ATOM   3064 N NZ  . LYS A 1 962  ? 199.929 216.721 221.307 1.00 57.77  ? 973  LYS A NZ  1 
ATOM   3065 N N   . ASN A 1 963  ? 204.025 212.754 220.376 1.00 59.56  ? 974  ASN A N   1 
ATOM   3066 C CA  . ASN A 1 963  ? 204.746 212.327 221.578 1.00 59.56  ? 974  ASN A CA  1 
ATOM   3067 C C   . ASN A 1 963  ? 205.285 210.906 221.435 1.00 59.56  ? 974  ASN A C   1 
ATOM   3068 O O   . ASN A 1 963  ? 205.230 210.100 222.366 1.00 59.56  ? 974  ASN A O   1 
ATOM   3069 C CB  . ASN A 1 963  ? 203.861 212.450 222.820 1.00 59.56  ? 974  ASN A CB  1 
ATOM   3070 C CG  . ASN A 1 963  ? 203.616 213.891 223.220 1.00 59.56  ? 974  ASN A CG  1 
ATOM   3071 O OD1 . ASN A 1 963  ? 204.436 214.769 222.955 1.00 59.56  ? 974  ASN A OD1 1 
ATOM   3072 N ND2 . ASN A 1 963  ? 202.481 214.141 223.862 1.00 59.56  ? 974  ASN A ND2 1 
ATOM   3073 N N   . VAL A 1 964  ? 205.815 210.596 220.255 1.00 55.89  ? 975  VAL A N   1 
ATOM   3074 C CA  . VAL A 1 964  ? 206.384 209.285 219.976 1.00 55.89  ? 975  VAL A CA  1 
ATOM   3075 C C   . VAL A 1 964  ? 207.755 209.472 219.343 1.00 55.89  ? 975  VAL A C   1 
ATOM   3076 O O   . VAL A 1 964  ? 208.062 210.524 218.774 1.00 55.89  ? 975  VAL A O   1 
ATOM   3077 C CB  . VAL A 1 964  ? 205.466 208.440 219.063 1.00 55.89  ? 975  VAL A CB  1 
ATOM   3078 C CG1 . VAL A 1 964  ? 205.686 208.794 217.603 1.00 55.89  ? 975  VAL A CG1 1 
ATOM   3079 C CG2 . VAL A 1 964  ? 205.694 206.957 219.300 1.00 55.89  ? 975  VAL A CG2 1 
ATOM   3080 N N   . GLU A 1 965  ? 208.589 208.443 219.460 1.00 57.39  ? 976  GLU A N   1 
ATOM   3081 C CA  . GLU A 1 965  ? 209.917 208.487 218.865 1.00 57.39  ? 976  GLU A CA  1 
ATOM   3082 C C   . GLU A 1 965  ? 209.825 208.333 217.351 1.00 57.39  ? 976  GLU A C   1 
ATOM   3083 O O   . GLU A 1 965  ? 209.036 207.535 216.838 1.00 57.39  ? 976  GLU A O   1 
ATOM   3084 C CB  . GLU A 1 965  ? 210.800 207.388 219.457 1.00 57.39  ? 976  GLU A CB  1 
ATOM   3085 C CG  . GLU A 1 965  ? 212.244 207.424 218.985 1.00 57.39  ? 976  GLU A CG  1 
ATOM   3086 C CD  . GLU A 1 965  ? 213.023 208.587 219.571 1.00 57.39  ? 976  GLU A CD  1 
ATOM   3087 O OE1 . GLU A 1 965  ? 212.574 209.157 220.588 1.00 57.39  ? 976  GLU A OE1 1 
ATOM   3088 O OE2 . GLU A 1 965  ? 214.086 208.932 219.014 1.00 57.39  ? 976  GLU A OE2 1 
ATOM   3089 N N   . ASP A 1 966  ? 210.637 209.110 216.637 1.00 55.49  ? 977  ASP A N   1 
ATOM   3090 C CA  . ASP A 1 966  ? 210.642 209.051 215.182 1.00 55.49  ? 977  ASP A CA  1 
ATOM   3091 C C   . ASP A 1 966  ? 211.175 207.705 214.703 1.00 55.49  ? 977  ASP A C   1 
ATOM   3092 O O   . ASP A 1 966  ? 212.082 207.126 215.307 1.00 55.49  ? 977  ASP A O   1 
ATOM   3093 C CB  . ASP A 1 966  ? 211.488 210.187 214.608 1.00 55.49  ? 977  ASP A CB  1 
ATOM   3094 C CG  . ASP A 1 966  ? 211.107 210.535 213.181 1.00 55.49  ? 977  ASP A CG  1 
ATOM   3095 O OD1 . ASP A 1 966  ? 210.689 209.626 212.434 1.00 55.49  ? 977  ASP A OD1 1 
ATOM   3096 O OD2 . ASP A 1 966  ? 211.227 211.720 212.806 1.00 55.49  ? 977  ASP A OD2 1 
ATOM   3097 N N   . ASN A 1 967  ? 210.601 207.209 213.609 1.00 50.43  ? 978  ASN A N   1 
ATOM   3098 C CA  . ASN A 1 967  ? 210.990 205.920 213.058 1.00 50.43  ? 978  ASN A CA  1 
ATOM   3099 C C   . ASN A 1 967  ? 210.756 205.933 211.554 1.00 50.43  ? 978  ASN A C   1 
ATOM   3100 O O   . ASN A 1 967  ? 209.977 206.735 211.034 1.00 50.43  ? 978  ASN A O   1 
ATOM   3101 C CB  . ASN A 1 967  ? 210.211 204.775 213.717 1.00 50.43  ? 978  ASN A CB  1 
ATOM   3102 C CG  . ASN A 1 967  ? 210.888 203.432 213.542 1.00 50.43  ? 978  ASN A CG  1 
ATOM   3103 O OD1 . ASN A 1 967  ? 212.054 203.358 213.157 1.00 50.43  ? 978  ASN A OD1 1 
ATOM   3104 N ND2 . ASN A 1 967  ? 210.159 202.360 213.827 1.00 50.43  ? 978  ASN A ND2 1 
ATOM   3105 N N   . TRP A 1 968  ? 211.447 205.034 210.857 1.00 47.48  ? 979  TRP A N   1 
ATOM   3106 C CA  . TRP A 1 968  ? 211.282 204.878 209.420 1.00 47.48  ? 979  TRP A CA  1 
ATOM   3107 C C   . TRP A 1 968  ? 211.410 203.407 209.055 1.00 47.48  ? 979  TRP A C   1 
ATOM   3108 O O   . TRP A 1 968  ? 212.109 202.644 209.727 1.00 47.48  ? 979  TRP A O   1 
ATOM   3109 C CB  . TRP A 1 968  ? 212.304 205.714 208.635 1.00 47.48  ? 979  TRP A CB  1 
ATOM   3110 C CG  . TRP A 1 968  ? 213.733 205.397 208.955 1.00 47.48  ? 979  TRP A CG  1 
ATOM   3111 C CD1 . TRP A 1 968  ? 214.517 206.004 209.891 1.00 47.48  ? 979  TRP A CD1 1 
ATOM   3112 C CD2 . TRP A 1 968  ? 214.553 204.402 208.329 1.00 47.48  ? 979  TRP A CD2 1 
ATOM   3113 N NE1 . TRP A 1 968  ? 215.773 205.447 209.891 1.00 47.48  ? 979  TRP A NE1 1 
ATOM   3114 C CE2 . TRP A 1 968  ? 215.820 204.461 208.941 1.00 47.48  ? 979  TRP A CE2 1 
ATOM   3115 C CE3 . TRP A 1 968  ? 214.337 203.466 207.313 1.00 47.48  ? 979  TRP A CE3 1 
ATOM   3116 C CZ2 . TRP A 1 968  ? 216.867 203.619 208.572 1.00 47.48  ? 979  TRP A CZ2 1 
ATOM   3117 C CZ3 . TRP A 1 968  ? 215.378 202.632 206.948 1.00 47.48  ? 979  TRP A CZ3 1 
ATOM   3118 C CH2 . TRP A 1 968  ? 216.626 202.714 207.576 1.00 47.48  ? 979  TRP A CH2 1 
ATOM   3119 N N   . ARG A 1 969  ? 210.728 203.014 207.981 1.00 43.97  ? 980  ARG A N   1 
ATOM   3120 C CA  . ARG A 1 969  ? 210.717 201.628 207.540 1.00 43.97  ? 980  ARG A CA  1 
ATOM   3121 C C   . ARG A 1 969  ? 210.914 201.567 206.033 1.00 43.97  ? 980  ARG A C   1 
ATOM   3122 O O   . ARG A 1 969  ? 210.610 202.520 205.311 1.00 43.97  ? 980  ARG A O   1 
ATOM   3123 C CB  . ARG A 1 969  ? 209.409 200.919 207.919 1.00 43.97  ? 980  ARG A CB  1 
ATOM   3124 C CG  . ARG A 1 969  ? 208.200 201.371 207.115 1.00 43.97  ? 980  ARG A CG  1 
ATOM   3125 C CD  . ARG A 1 969  ? 206.959 200.581 207.498 1.00 43.97  ? 980  ARG A CD  1 
ATOM   3126 N NE  . ARG A 1 969  ? 205.812 200.920 206.665 1.00 43.97  ? 980  ARG A NE  1 
ATOM   3127 C CZ  . ARG A 1 969  ? 204.556 200.615 206.962 1.00 43.97  ? 980  ARG A CZ  1 
ATOM   3128 N NH1 . ARG A 1 969  ? 204.247 199.962 208.070 1.00 43.97  ? 980  ARG A NH1 1 
ATOM   3129 N NH2 . ARG A 1 969  ? 203.586 200.975 206.127 1.00 43.97  ? 980  ARG A NH2 1 
ATOM   3130 N N   . VAL A 1 970  ? 211.434 200.433 205.568 1.00 42.86  ? 981  VAL A N   1 
ATOM   3131 C CA  . VAL A 1 970  ? 211.630 200.160 204.147 1.00 42.86  ? 981  VAL A CA  1 
ATOM   3132 C C   . VAL A 1 970  ? 211.122 198.744 203.905 1.00 42.86  ? 981  VAL A C   1 
ATOM   3133 O O   . VAL A 1 970  ? 211.791 197.768 204.262 1.00 42.86  ? 981  VAL A O   1 
ATOM   3134 C CB  . VAL A 1 970  ? 213.093 200.304 203.713 1.00 42.86  ? 981  VAL A CB  1 
ATOM   3135 C CG1 . VAL A 1 970  ? 213.256 199.891 202.258 1.00 42.86  ? 981  VAL A CG1 1 
ATOM   3136 C CG2 . VAL A 1 970  ? 213.576 201.732 203.920 1.00 42.86  ? 981  VAL A CG2 1 
ATOM   3137 N N   . ARG A 1 971  ? 209.944 198.625 203.304 1.00 45.62  ? 982  ARG A N   1 
ATOM   3138 C CA  . ARG A 1 971  ? 209.324 197.334 203.051 1.00 45.62  ? 982  ARG A CA  1 
ATOM   3139 C C   . ARG A 1 971  ? 209.512 196.921 201.595 1.00 45.62  ? 982  ARG A C   1 
ATOM   3140 O O   . ARG A 1 971  ? 209.656 197.755 200.698 1.00 45.62  ? 982  ARG A O   1 
ATOM   3141 C CB  . ARG A 1 971  ? 207.834 197.373 203.397 1.00 45.62  ? 982  ARG A CB  1 
ATOM   3142 C CG  . ARG A 1 971  ? 207.547 197.670 204.859 1.00 45.62  ? 982  ARG A CG  1 
ATOM   3143 C CD  . ARG A 1 971  ? 206.118 197.310 205.226 1.00 45.62  ? 982  ARG A CD  1 
ATOM   3144 N NE  . ARG A 1 971  ? 205.148 198.110 204.488 1.00 45.62  ? 982  ARG A NE  1 
ATOM   3145 C CZ  . ARG A 1 971  ? 203.834 197.949 204.563 1.00 45.62  ? 982  ARG A CZ  1 
ATOM   3146 N NH1 . ARG A 1 971  ? 203.294 197.025 205.341 1.00 45.62  ? 982  ARG A NH1 1 
ATOM   3147 N NH2 . ARG A 1 971  ? 203.042 198.735 203.840 1.00 45.62  ? 982  ARG A NH2 1 
ATOM   3148 N N   . TRP A 1 972  ? 209.505 195.609 201.373 1.00 50.83  ? 983  TRP A N   1 
ATOM   3149 C CA  . TRP A 1 972  ? 209.671 195.050 200.038 1.00 50.83  ? 983  TRP A CA  1 
ATOM   3150 C C   . TRP A 1 972  ? 208.839 193.783 199.933 1.00 50.83  ? 983  TRP A C   1 
ATOM   3151 O O   . TRP A 1 972  ? 208.996 192.868 200.746 1.00 50.83  ? 983  TRP A O   1 
ATOM   3152 C CB  . TRP A 1 972  ? 211.146 194.752 199.743 1.00 50.83  ? 983  TRP A CB  1 
ATOM   3153 C CG  . TRP A 1 972  ? 211.361 193.644 198.753 1.00 50.83  ? 983  TRP A CG  1 
ATOM   3154 C CD1 . TRP A 1 972  ? 211.550 192.321 199.029 1.00 50.83  ? 983  TRP A CD1 1 
ATOM   3155 C CD2 . TRP A 1 972  ? 211.418 193.768 197.327 1.00 50.83  ? 983  TRP A CD2 1 
ATOM   3156 N NE1 . TRP A 1 972  ? 211.715 191.613 197.864 1.00 50.83  ? 983  TRP A NE1 1 
ATOM   3157 C CE2 . TRP A 1 972  ? 211.639 192.478 196.805 1.00 50.83  ? 983  TRP A CE2 1 
ATOM   3158 C CE3 . TRP A 1 972  ? 211.301 194.843 196.441 1.00 50.83  ? 983  TRP A CE3 1 
ATOM   3159 C CZ2 . TRP A 1 972  ? 211.746 192.235 195.437 1.00 50.83  ? 983  TRP A CZ2 1 
ATOM   3160 C CZ3 . TRP A 1 972  ? 211.407 194.599 195.084 1.00 50.83  ? 983  TRP A CZ3 1 
ATOM   3161 C CH2 . TRP A 1 972  ? 211.628 193.306 194.595 1.00 50.83  ? 983  TRP A CH2 1 
ATOM   3162 N N   . MET A 1 973  ? 207.958 193.734 198.936 1.00 55.91  ? 984  MET A N   1 
ATOM   3163 C CA  . MET A 1 973  ? 207.091 192.587 198.711 1.00 55.91  ? 984  MET A CA  1 
ATOM   3164 C C   . MET A 1 973  ? 207.207 192.131 197.265 1.00 55.91  ? 984  MET A C   1 
ATOM   3165 O O   . MET A 1 973  ? 207.256 192.954 196.346 1.00 55.91  ? 984  MET A O   1 
ATOM   3166 C CB  . MET A 1 973  ? 205.628 192.915 199.035 1.00 55.91  ? 984  MET A CB  1 
ATOM   3167 C CG  . MET A 1 973  ? 205.438 193.801 200.254 1.00 55.91  ? 984  MET A CG  1 
ATOM   3168 S SD  . MET A 1 973  ? 203.755 194.429 200.397 1.00 55.91  ? 984  MET A SD  1 
ATOM   3169 C CE  . MET A 1 973  ? 203.469 194.231 202.154 1.00 55.91  ? 984  MET A CE  1 
ATOM   3170 N N   . THR A 1 974  ? 207.249 190.815 197.072 1.00 58.81  ? 985  THR A N   1 
ATOM   3171 C CA  . THR A 1 974  ? 207.304 190.231 195.741 1.00 58.81  ? 985  THR A CA  1 
ATOM   3172 C C   . THR A 1 974  ? 206.541 188.916 195.758 1.00 58.81  ? 985  THR A C   1 
ATOM   3173 O O   . THR A 1 974  ? 206.360 188.295 196.808 1.00 58.81  ? 985  THR A O   1 
ATOM   3174 C CB  . THR A 1 974  ? 208.747 190.009 195.272 1.00 58.81  ? 985  THR A CB  1 
ATOM   3175 O OG1 . THR A 1 974  ? 208.743 189.413 193.969 1.00 58.81  ? 985  THR A OG1 1 
ATOM   3176 C CG2 . THR A 1 974  ? 209.489 189.100 196.238 1.00 58.81  ? 985  THR A CG2 1 
ATOM   3177 N N   . GLY A 1 975  ? 206.091 188.496 194.579 1.00 66.71  ? 986  GLY A N   1 
ATOM   3178 C CA  . GLY A 1 975  ? 205.320 187.273 194.483 1.00 66.71  ? 986  GLY A CA  1 
ATOM   3179 C C   . GLY A 1 975  ? 205.165 186.731 193.079 1.00 66.71  ? 986  GLY A C   1 
ATOM   3180 O O   . GLY A 1 975  ? 204.968 187.488 192.124 1.00 66.71  ? 986  GLY A O   1 
ATOM   3181 N N   . TYR A 1 976  ? 205.248 185.402 192.977 1.00 75.86  ? 987  TYR A N   1 
ATOM   3182 C CA  . TYR A 1 976  ? 205.018 184.725 191.677 1.00 75.86  ? 987  TYR A CA  1 
ATOM   3183 C C   . TYR A 1 976  ? 203.788 183.855 191.842 1.00 75.86  ? 987  TYR A C   1 
ATOM   3184 O O   . TYR A 1 976  ? 203.776 183.003 192.751 1.00 75.86  ? 987  TYR A O   1 
ATOM   3185 C CB  . TYR A 1 976  ? 206.189 183.853 191.222 1.00 75.86  ? 987  TYR A CB  1 
ATOM   3186 C CG  . TYR A 1 976  ? 205.786 182.824 190.174 1.00 75.86  ? 987  TYR A CG  1 
ATOM   3187 C CD1 . TYR A 1 976  ? 205.700 183.169 188.832 1.00 75.86  ? 987  TYR A CD1 1 
ATOM   3188 C CD2 . TYR A 1 976  ? 205.496 181.511 190.526 1.00 75.86  ? 987  TYR A CD2 1 
ATOM   3189 C CE1 . TYR A 1 976  ? 205.329 182.243 187.873 1.00 75.86  ? 987  TYR A CE1 1 
ATOM   3190 C CE2 . TYR A 1 976  ? 205.123 180.576 189.576 1.00 75.86  ? 987  TYR A CE2 1 
ATOM   3191 C CZ  . TYR A 1 976  ? 205.042 180.943 188.245 1.00 75.86  ? 987  TYR A CZ  1 
ATOM   3192 O OH  . TYR A 1 976  ? 204.681 180.026 187.301 1.00 75.86  ? 987  TYR A OH  1 
ATOM   3193 N N   . TYR A 1 977  ? 202.776 184.069 191.010 1.00 81.73  ? 988  TYR A N   1 
ATOM   3194 C CA  . TYR A 1 977  ? 201.534 183.309 191.051 1.00 81.73  ? 988  TYR A CA  1 
ATOM   3195 C C   . TYR A 1 977  ? 201.323 182.607 189.717 1.00 81.73  ? 988  TYR A C   1 
ATOM   3196 O O   . TYR A 1 977  ? 201.488 183.209 188.651 1.00 81.73  ? 988  TYR A O   1 
ATOM   3197 C CB  . TYR A 1 977  ? 200.341 184.220 191.401 1.00 81.73  ? 988  TYR A CB  1 
ATOM   3198 C CG  . TYR A 1 977  ? 199.598 184.821 190.225 1.00 81.73  ? 988  TYR A CG  1 
ATOM   3199 C CD1 . TYR A 1 977  ? 199.952 186.065 189.720 1.00 81.73  ? 988  TYR A CD1 1 
ATOM   3200 C CD2 . TYR A 1 977  ? 198.519 184.163 189.647 1.00 81.73  ? 988  TYR A CD2 1 
ATOM   3201 C CE1 . TYR A 1 977  ? 199.271 186.624 188.655 1.00 81.73  ? 988  TYR A CE1 1 
ATOM   3202 C CE2 . TYR A 1 977  ? 197.833 184.714 188.582 1.00 81.73  ? 988  TYR A CE2 1 
ATOM   3203 C CZ  . TYR A 1 977  ? 198.213 185.945 188.090 1.00 81.73  ? 988  TYR A CZ  1 
ATOM   3204 O OH  . TYR A 1 977  ? 197.531 186.499 187.031 1.00 81.73  ? 988  TYR A OH  1 
ATOM   3205 N N   . TYR A 1 978  ? 200.974 181.324 189.785 1.00 81.47  ? 989  TYR A N   1 
ATOM   3206 C CA  . TYR A 1 978  ? 200.777 180.484 188.610 1.00 81.47  ? 989  TYR A CA  1 
ATOM   3207 C C   . TYR A 1 978  ? 199.306 180.106 188.521 1.00 81.47  ? 989  TYR A C   1 
ATOM   3208 O O   . TYR A 1 978  ? 198.747 179.556 189.475 1.00 81.47  ? 989  TYR A O   1 
ATOM   3209 C CB  . TYR A 1 978  ? 201.653 179.231 188.680 1.00 81.47  ? 989  TYR A CB  1 
ATOM   3210 C CG  . TYR A 1 978  ? 201.352 178.201 187.615 1.00 81.47  ? 989  TYR A CG  1 
ATOM   3211 C CD1 . TYR A 1 978  ? 201.785 178.377 186.308 1.00 81.47  ? 989  TYR A CD1 1 
ATOM   3212 C CD2 . TYR A 1 978  ? 200.638 177.050 187.918 1.00 81.47  ? 989  TYR A CD2 1 
ATOM   3213 C CE1 . TYR A 1 978  ? 201.514 177.436 185.332 1.00 81.47  ? 989  TYR A CE1 1 
ATOM   3214 C CE2 . TYR A 1 978  ? 200.362 176.104 186.950 1.00 81.47  ? 989  TYR A CE2 1 
ATOM   3215 C CZ  . TYR A 1 978  ? 200.802 176.302 185.658 1.00 81.47  ? 989  TYR A CZ  1 
ATOM   3216 O OH  . TYR A 1 978  ? 200.528 175.362 184.691 1.00 81.47  ? 989  TYR A OH  1 
ATOM   3217 N N   . LYS A 1 979  ? 198.688 180.391 187.378 1.00 86.80  ? 990  LYS A N   1 
ATOM   3218 C CA  . LYS A 1 979  ? 197.268 180.123 187.172 1.00 86.80  ? 990  LYS A CA  1 
ATOM   3219 C C   . LYS A 1 979  ? 197.099 178.692 186.667 1.00 86.80  ? 990  LYS A C   1 
ATOM   3220 O O   . LYS A 1 979  ? 197.432 178.385 185.518 1.00 86.80  ? 990  LYS A O   1 
ATOM   3221 C CB  . LYS A 1 979  ? 196.664 181.135 186.200 1.00 86.80  ? 990  LYS A CB  1 
ATOM   3222 C CG  . LYS A 1 979  ? 197.496 181.397 184.950 1.00 86.80  ? 990  LYS A CG  1 
ATOM   3223 C CD  . LYS A 1 979  ? 196.936 182.556 184.143 1.00 86.80  ? 990  LYS A CD  1 
ATOM   3224 C CE  . LYS A 1 979  ? 197.068 183.868 184.896 1.00 86.80  ? 990  LYS A CE  1 
ATOM   3225 N NZ  . LYS A 1 979  ? 198.434 184.041 185.462 1.00 86.80  ? 990  LYS A NZ  1 
ATOM   3226 N N   . VAL A 1 980  ? 196.582 177.816 187.533 1.00 80.55  ? 991  VAL A N   1 
ATOM   3227 C CA  . VAL A 1 980  ? 196.353 176.395 187.133 1.00 80.55  ? 991  VAL A CA  1 
ATOM   3228 C C   . VAL A 1 980  ? 195.195 176.367 186.126 1.00 80.55  ? 991  VAL A C   1 
ATOM   3229 O O   . VAL A 1 980  ? 195.307 175.641 185.116 1.00 80.55  ? 991  VAL A O   1 
ATOM   3230 C CB  . VAL A 1 980  ? 196.055 175.503 188.351 1.00 80.55  ? 991  VAL A CB  1 
ATOM   3231 C CG1 . VAL A 1 980  ? 195.802 174.056 187.948 1.00 80.55  ? 991  VAL A CG1 1 
ATOM   3232 C CG2 . VAL A 1 980  ? 197.165 175.585 189.392 1.00 80.55  ? 991  VAL A CG2 1 
ATOM   3233 N N   . ILE A 1 981  ? 194.134 177.130 186.392 1.00 83.35  ? 992  ILE A N   1 
ATOM   3234 C CA  . ILE A 1 981  ? 192.970 177.209 185.459 1.00 83.35  ? 992  ILE A CA  1 
ATOM   3235 C C   . ILE A 1 981  ? 192.784 178.681 185.062 1.00 83.35  ? 992  ILE A C   1 
ATOM   3236 O O   . ILE A 1 981  ? 192.682 179.526 185.975 1.00 83.35  ? 992  ILE A O   1 
ATOM   3237 C CB  . ILE A 1 981  ? 191.703 176.621 186.105 1.00 83.35  ? 992  ILE A CB  1 
ATOM   3238 C CG1 . ILE A 1 981  ? 191.891 175.152 186.476 1.00 83.35  ? 992  ILE A CG1 1 
ATOM   3239 C CG2 . ILE A 1 981  ? 190.485 176.823 185.204 1.00 83.35  ? 992  ILE A CG2 1 
ATOM   3240 C CD1 . ILE A 1 981  ? 190.684 174.528 187.151 1.00 83.35  ? 992  ILE A CD1 1 
ATOM   3241 N N   . ASN A 1 982  ? 192.744 178.972 183.765 1.00 85.14  ? 993  ASN A N   1 
ATOM   3242 C CA  . ASN A 1 982  ? 192.625 180.333 183.249 1.00 85.14  ? 993  ASN A CA  1 
ATOM   3243 C C   . ASN A 1 982  ? 191.327 180.488 182.466 1.00 85.14  ? 993  ASN A C   1 
ATOM   3244 O O   . ASN A 1 982  ? 191.285 181.067 181.379 1.00 85.14  ? 993  ASN A O   1 
ATOM   3245 C CB  . ASN A 1 982  ? 193.834 180.692 182.389 1.00 85.14  ? 993  ASN A CB  1 
ATOM   3246 C CG  . ASN A 1 982  ? 193.924 182.178 182.099 1.00 85.14  ? 993  ASN A CG  1 
ATOM   3247 O OD1 . ASN A 1 982  ? 193.355 182.998 182.820 1.00 85.14  ? 993  ASN A OD1 1 
ATOM   3248 N ND2 . ASN A 1 982  ? 194.640 182.532 181.039 1.00 85.14  ? 993  ASN A ND2 1 
ATOM   3249 N N   . GLN A 1 983  ? 190.243 179.956 183.018 1.00 85.16  ? 994  GLN A N   1 
ATOM   3250 C CA  . GLN A 1 983  ? 188.932 180.084 182.404 1.00 85.16  ? 994  GLN A CA  1 
ATOM   3251 C C   . GLN A 1 983  ? 188.333 181.452 182.730 1.00 85.16  ? 994  GLN A C   1 
ATOM   3252 O O   . GLN A 1 983  ? 188.738 182.128 183.678 1.00 85.16  ? 994  GLN A O   1 
ATOM   3253 C CB  . GLN A 1 983  ? 188.012 178.956 182.875 1.00 85.16  ? 994  GLN A CB  1 
ATOM   3254 C CG  . GLN A 1 983  ? 186.794 178.724 181.993 1.00 85.16  ? 994  GLN A CG  1 
ATOM   3255 C CD  . GLN A 1 983  ? 185.815 177.739 182.598 1.00 85.16  ? 994  GLN A CD  1 
ATOM   3256 O OE1 . GLN A 1 983  ? 184.651 178.065 182.830 1.00 85.16  ? 994  GLN A OE1 1 
ATOM   3257 N NE2 . GLN A 1 983  ? 186.283 176.524 182.858 1.00 85.16  ? 994  GLN A NE2 1 
ATOM   3258 N N   . ASN A 1 984  ? 187.359 181.864 181.914 1.00 82.01  ? 995  ASN A N   1 
ATOM   3259 C CA  . ASN A 1 984  ? 186.722 183.161 182.119 1.00 82.01  ? 995  ASN A CA  1 
ATOM   3260 C C   . ASN A 1 984  ? 185.983 183.216 183.451 1.00 82.01  ? 995  ASN A C   1 
ATOM   3261 O O   . ASN A 1 984  ? 186.044 184.228 184.159 1.00 82.01  ? 995  ASN A O   1 
ATOM   3262 C CB  . ASN A 1 984  ? 185.768 183.464 180.964 1.00 82.01  ? 995  ASN A CB  1 
ATOM   3263 C CG  . ASN A 1 984  ? 186.498 183.833 179.688 1.00 82.01  ? 995  ASN A CG  1 
ATOM   3264 O OD1 . ASN A 1 984  ? 187.717 184.003 179.683 1.00 82.01  ? 995  ASN A OD1 1 
ATOM   3265 N ND2 . ASN A 1 984  ? 185.753 183.959 178.596 1.00 82.01  ? 995  ASN A ND2 1 
ATOM   3266 N N   . ASN A 1 985  ? 185.280 182.142 183.810 1.00 81.72  ? 996  ASN A N   1 
ATOM   3267 C CA  . ASN A 1 985  ? 184.489 182.097 185.033 1.00 81.72  ? 996  ASN A CA  1 
ATOM   3268 C C   . ASN A 1 985  ? 185.139 181.263 186.130 1.00 81.72  ? 996  ASN A C   1 
ATOM   3269 O O   . ASN A 1 985  ? 184.499 181.000 187.153 1.00 81.72  ? 996  ASN A O   1 
ATOM   3270 C CB  . ASN A 1 985  ? 183.087 181.564 184.732 1.00 81.72  ? 996  ASN A CB  1 
ATOM   3271 C CG  . ASN A 1 985  ? 182.291 182.492 183.836 1.00 81.72  ? 996  ASN A CG  1 
ATOM   3272 O OD1 . ASN A 1 985  ? 182.430 183.713 183.909 1.00 81.72  ? 996  ASN A OD1 1 
ATOM   3273 N ND2 . ASN A 1 985  ? 181.452 181.917 182.983 1.00 81.72  ? 996  ASN A ND2 1 
ATOM   3274 N N   . ARG A 1 986  ? 186.388 180.841 185.948 1.00 82.57  ? 997  ARG A N   1 
ATOM   3275 C CA  . ARG A 1 986  ? 187.074 180.032 186.950 1.00 82.57  ? 997  ARG A CA  1 
ATOM   3276 C C   . ARG A 1 986  ? 188.562 180.333 186.889 1.00 82.57  ? 997  ARG A C   1 
ATOM   3277 O O   . ARG A 1 986  ? 189.159 180.287 185.810 1.00 82.57  ? 997  ARG A O   1 
ATOM   3278 C CB  . ARG A 1 986  ? 186.815 178.541 186.723 1.00 82.57  ? 997  ARG A CB  1 
ATOM   3279 C CG  . ARG A 1 986  ? 187.314 177.645 187.843 1.00 82.57  ? 997  ARG A CG  1 
ATOM   3280 C CD  . ARG A 1 986  ? 186.862 176.210 187.637 1.00 82.57  ? 997  ARG A CD  1 
ATOM   3281 N NE  . ARG A 1 986  ? 185.422 176.118 187.431 1.00 82.57  ? 997  ARG A NE  1 
ATOM   3282 C CZ  . ARG A 1 986  ? 184.769 174.987 187.198 1.00 82.57  ? 997  ARG A CZ  1 
ATOM   3283 N NH1 . ARG A 1 986  ? 185.399 173.826 187.134 1.00 82.57  ? 997  ARG A NH1 1 
ATOM   3284 N NH2 . ARG A 1 986  ? 183.451 175.023 187.025 1.00 82.57  ? 997  ARG A NH2 1 
ATOM   3285 N N   . ARG A 1 987  ? 189.157 180.636 188.042 1.00 79.73  ? 998  ARG A N   1 
ATOM   3286 C CA  . ARG A 1 987  ? 190.578 180.952 188.125 1.00 79.73  ? 998  ARG A CA  1 
ATOM   3287 C C   . ARG A 1 987  ? 191.132 180.393 189.425 1.00 79.73  ? 998  ARG A C   1 
ATOM   3288 O O   . ARG A 1 987  ? 190.688 180.785 190.508 1.00 79.73  ? 998  ARG A O   1 
ATOM   3289 C CB  . ARG A 1 987  ? 190.813 182.464 188.046 1.00 79.73  ? 998  ARG A CB  1 
ATOM   3290 C CG  . ARG A 1 987  ? 192.200 182.854 187.561 1.00 79.73  ? 998  ARG A CG  1 
ATOM   3291 C CD  . ARG A 1 987  ? 192.190 184.208 186.864 1.00 79.73  ? 998  ARG A CD  1 
ATOM   3292 N NE  . ARG A 1 987  ? 191.347 184.213 185.674 1.00 79.73  ? 998  ARG A NE  1 
ATOM   3293 C CZ  . ARG A 1 987  ? 190.169 184.816 185.592 1.00 79.73  ? 998  ARG A CZ  1 
ATOM   3294 N NH1 . ARG A 1 987  ? 189.659 185.479 186.617 1.00 79.73  ? 998  ARG A NH1 1 
ATOM   3295 N NH2 . ARG A 1 987  ? 189.486 184.754 184.452 1.00 79.73  ? 998  ARG A NH2 1 
ATOM   3296 N N   . VAL A 1 988  ? 192.096 179.483 189.318 1.00 79.45  ? 999  VAL A N   1 
ATOM   3297 C CA  . VAL A 1 988  ? 192.769 178.894 190.470 1.00 79.45  ? 999  VAL A CA  1 
ATOM   3298 C C   . VAL A 1 988  ? 194.256 179.192 190.340 1.00 79.45  ? 999  VAL A C   1 
ATOM   3299 O O   . VAL A 1 988  ? 194.880 178.829 189.335 1.00 79.45  ? 999  VAL A O   1 
ATOM   3300 C CB  . VAL A 1 988  ? 192.518 177.382 190.571 1.00 79.45  ? 999  VAL A CB  1 
ATOM   3301 C CG1 . VAL A 1 988  ? 193.411 176.764 191.635 1.00 79.45  ? 999  VAL A CG1 1 
ATOM   3302 C CG2 . VAL A 1 988  ? 191.052 177.107 190.870 1.00 79.45  ? 999  VAL A CG2 1 
ATOM   3303 N N   . THR A 1 989  ? 194.822 179.848 191.352 1.00 78.89  ? 1000 THR A N   1 
ATOM   3304 C CA  . THR A 1 989  ? 196.216 180.267 191.328 1.00 78.89  ? 1000 THR A CA  1 
ATOM   3305 C C   . THR A 1 989  ? 196.959 179.693 192.525 1.00 78.89  ? 1000 THR A C   1 
ATOM   3306 O O   . THR A 1 989  ? 196.474 179.757 193.659 1.00 78.89  ? 1000 THR A O   1 
ATOM   3307 C CB  . THR A 1 989  ? 196.349 181.799 191.332 1.00 78.89  ? 1000 THR A CB  1 
ATOM   3308 O OG1 . THR A 1 989  ? 196.377 182.275 192.684 1.00 78.89  ? 1000 THR A OG1 1 
ATOM   3309 C CG2 . THR A 1 989  ? 195.189 182.448 190.591 1.00 78.89  ? 1000 THR A CG2 1 
ATOM   3310 N N   . ILE A 1 990  ? 198.138 179.133 192.262 1.00 72.83  ? 1001 ILE A N   1 
ATOM   3311 C CA  . ILE A 1 990  ? 199.042 178.644 193.296 1.00 72.83  ? 1001 ILE A CA  1 
ATOM   3312 C C   . ILE A 1 990  ? 200.416 179.239 193.030 1.00 72.83  ? 1001 ILE A C   1 
ATOM   3313 O O   . ILE A 1 990  ? 200.927 179.148 191.908 1.00 72.83  ? 1001 ILE A O   1 
ATOM   3314 C CB  . ILE A 1 990  ? 199.114 177.105 193.319 1.00 72.83  ? 1001 ILE A CB  1 
ATOM   3315 C CG1 . ILE A 1 990  ? 197.746 176.507 193.651 1.00 72.83  ? 1001 ILE A CG1 1 
ATOM   3316 C CG2 . ILE A 1 990  ? 200.160 176.634 194.318 1.00 72.83  ? 1001 ILE A CG2 1 
ATOM   3317 C CD1 . ILE A 1 990  ? 197.753 174.999 193.776 1.00 72.83  ? 1001 ILE A CD1 1 
ATOM   3318 N N   . GLY A 1 991  ? 201.009 179.841 194.044 1.00 69.01  ? 1002 GLY A N   1 
ATOM   3319 C CA  . GLY A 1 991  ? 202.292 180.497 193.885 1.00 69.01  ? 1002 GLY A CA  1 
ATOM   3320 C C   . GLY A 1 991  ? 203.055 180.650 195.180 1.00 69.01  ? 1002 GLY A C   1 
ATOM   3321 O O   . GLY A 1 991  ? 202.800 179.947 196.160 1.00 69.01  ? 1002 GLY A O   1 
ATOM   3322 N N   . LEU A 1 992  ? 204.007 181.582 195.176 1.00 65.21  ? 1003 LEU A N   1 
ATOM   3323 C CA  . LEU A 1 992  ? 204.882 181.818 196.314 1.00 65.21  ? 1003 LEU A CA  1 
ATOM   3324 C C   . LEU A 1 992  ? 204.998 183.317 196.545 1.00 65.21  ? 1003 LEU A C   1 
ATOM   3325 O O   . LEU A 1 992  ? 205.056 184.094 195.589 1.00 65.21  ? 1003 LEU A O   1 
ATOM   3326 C CB  . LEU A 1 992  ? 206.268 181.203 196.081 1.00 65.21  ? 1003 LEU A CB  1 
ATOM   3327 C CG  . LEU A 1 992  ? 207.412 181.619 197.009 1.00 65.21  ? 1003 LEU A CG  1 
ATOM   3328 C CD1 . LEU A 1 992  ? 207.260 180.976 198.378 1.00 65.21  ? 1003 LEU A CD1 1 
ATOM   3329 C CD2 . LEU A 1 992  ? 208.758 181.271 196.395 1.00 65.21  ? 1003 LEU A CD2 1 
ATOM   3330 N N   . ASN A 1 993  ? 205.029 183.716 197.816 1.00 58.86  ? 1004 ASN A N   1 
ATOM   3331 C CA  . ASN A 1 993  ? 205.129 185.117 198.197 1.00 58.86  ? 1004 ASN A CA  1 
ATOM   3332 C C   . ASN A 1 993  ? 206.325 185.316 199.116 1.00 58.86  ? 1004 ASN A C   1 
ATOM   3333 O O   . ASN A 1 993  ? 206.651 184.440 199.923 1.00 58.86  ? 1004 ASN A O   1 
ATOM   3334 C CB  . ASN A 1 993  ? 203.851 185.598 198.894 1.00 58.86  ? 1004 ASN A CB  1 
ATOM   3335 C CG  . ASN A 1 993  ? 202.685 185.748 197.937 1.00 58.86  ? 1004 ASN A CG  1 
ATOM   3336 O OD1 . ASN A 1 993  ? 202.823 185.531 196.733 1.00 58.86  ? 1004 ASN A OD1 1 
ATOM   3337 N ND2 . ASN A 1 993  ? 201.527 186.121 198.469 1.00 58.86  ? 1004 ASN A ND2 1 
ATOM   3338 N N   . ASN A 1 994  ? 206.977 186.470 198.988 1.00 53.17  ? 1005 ASN A N   1 
ATOM   3339 C CA  . ASN A 1 994  ? 208.122 186.827 199.812 1.00 53.17  ? 1005 ASN A CA  1 
ATOM   3340 C C   . ASN A 1 994  ? 207.976 188.265 200.286 1.00 53.17  ? 1005 ASN A C   1 
ATOM   3341 O O   . ASN A 1 994  ? 207.594 189.146 199.510 1.00 53.17  ? 1005 ASN A O   1 
ATOM   3342 C CB  . ASN A 1 994  ? 209.437 186.657 199.041 1.00 53.17  ? 1005 ASN A CB  1 
ATOM   3343 C CG  . ASN A 1 994  ? 210.658 186.808 199.926 1.00 53.17  ? 1005 ASN A CG  1 
ATOM   3344 O OD1 . ASN A 1 994  ? 210.545 186.941 201.144 1.00 53.17  ? 1005 ASN A OD1 1 
ATOM   3345 N ND2 . ASN A 1 994  ? 211.836 186.788 199.315 1.00 53.17  ? 1005 ASN A ND2 1 
ATOM   3346 N N   . MET A 1 995  ? 208.279 188.498 201.562 1.00 49.17  ? 1006 MET A N   1 
ATOM   3347 C CA  . MET A 1 995  ? 208.186 189.828 202.152 1.00 49.17  ? 1006 MET A CA  1 
ATOM   3348 C C   . MET A 1 995  ? 209.393 190.074 203.044 1.00 49.17  ? 1006 MET A C   1 
ATOM   3349 O O   . MET A 1 995  ? 209.733 189.229 203.877 1.00 49.17  ? 1006 MET A O   1 
ATOM   3350 C CB  . MET A 1 995  ? 206.893 189.985 202.960 1.00 49.17  ? 1006 MET A CB  1 
ATOM   3351 C CG  . MET A 1 995  ? 205.663 190.265 202.114 1.00 49.17  ? 1006 MET A CG  1 
ATOM   3352 S SD  . MET A 1 995  ? 204.767 188.764 201.674 1.00 49.17  ? 1006 MET A SD  1 
ATOM   3353 C CE  . MET A 1 995  ? 203.918 188.414 203.211 1.00 49.17  ? 1006 MET A CE  1 
ATOM   3354 N N   . ILE A 1 996  ? 210.035 191.227 202.867 1.00 45.70  ? 1007 ILE A N   1 
ATOM   3355 C CA  . ILE A 1 996  ? 211.179 191.637 203.677 1.00 45.70  ? 1007 ILE A CA  1 
ATOM   3356 C C   . ILE A 1 996  ? 210.912 193.053 204.170 1.00 45.70  ? 1007 ILE A C   1 
ATOM   3357 O O   . ILE A 1 996  ? 210.711 193.967 203.361 1.00 45.70  ? 1007 ILE A O   1 
ATOM   3358 C CB  . ILE A 1 996  ? 212.500 191.573 202.897 1.00 45.70  ? 1007 ILE A CB  1 
ATOM   3359 C CG1 . ILE A 1 996  ? 212.704 190.181 202.296 1.00 45.70  ? 1007 ILE A CG1 1 
ATOM   3360 C CG2 . ILE A 1 996  ? 213.667 191.944 203.798 1.00 45.70  ? 1007 ILE A CG2 1 
ATOM   3361 C CD1 . ILE A 1 996  ? 214.009 190.024 201.548 1.00 45.70  ? 1007 ILE A CD1 1 
ATOM   3362 N N   . TRP A 1 997  ? 210.911 193.238 205.488 1.00 42.85  ? 1008 TRP A N   1 
ATOM   3363 C CA  . TRP A 1 997  ? 210.713 194.541 206.104 1.00 42.85  ? 1008 TRP A CA  1 
ATOM   3364 C C   . TRP A 1 997  ? 211.889 194.868 207.014 1.00 42.85  ? 1008 TRP A C   1 
ATOM   3365 O O   . TRP A 1 997  ? 212.584 193.973 207.504 1.00 42.85  ? 1008 TRP A O   1 
ATOM   3366 C CB  . TRP A 1 997  ? 209.409 194.598 206.917 1.00 42.85  ? 1008 TRP A CB  1 
ATOM   3367 C CG  . TRP A 1 997  ? 208.197 194.086 206.197 1.00 42.85  ? 1008 TRP A CG  1 
ATOM   3368 C CD1 . TRP A 1 997  ? 207.979 194.085 204.851 1.00 42.85  ? 1008 TRP A CD1 1 
ATOM   3369 C CD2 . TRP A 1 997  ? 207.030 193.506 206.792 1.00 42.85  ? 1008 TRP A CD2 1 
ATOM   3370 N NE1 . TRP A 1 997  ? 206.752 193.535 204.569 1.00 42.85  ? 1008 TRP A NE1 1 
ATOM   3371 C CE2 . TRP A 1 997  ? 206.149 193.173 205.745 1.00 42.85  ? 1008 TRP A CE2 1 
ATOM   3372 C CE3 . TRP A 1 997  ? 206.646 193.235 208.108 1.00 42.85  ? 1008 TRP A CE3 1 
ATOM   3373 C CZ2 . TRP A 1 997  ? 204.909 192.582 205.972 1.00 42.85  ? 1008 TRP A CZ2 1 
ATOM   3374 C CZ3 . TRP A 1 997  ? 205.415 192.648 208.332 1.00 42.85  ? 1008 TRP A CZ3 1 
ATOM   3375 C CH2 . TRP A 1 997  ? 204.561 192.328 207.270 1.00 42.85  ? 1008 TRP A CH2 1 
ATOM   3376 N N   . HIS A 1 998  ? 212.107 196.163 207.233 1.00 43.99  ? 1009 HIS A N   1 
ATOM   3377 C CA  . HIS A 1 998  ? 213.175 196.638 208.107 1.00 43.99  ? 1009 HIS A CA  1 
ATOM   3378 C C   . HIS A 1 998  ? 212.722 197.921 208.784 1.00 43.99  ? 1009 HIS A C   1 
ATOM   3379 O O   . HIS A 1 998  ? 212.366 198.888 208.104 1.00 43.99  ? 1009 HIS A O   1 
ATOM   3380 C CB  . HIS A 1 998  ? 214.470 196.875 207.326 1.00 43.99  ? 1009 HIS A CB  1 
ATOM   3381 C CG  . HIS A 1 998  ? 215.512 197.619 208.100 1.00 43.99  ? 1009 HIS A CG  1 
ATOM   3382 N ND1 . HIS A 1 998  ? 216.280 197.024 209.077 1.00 43.99  ? 1009 HIS A ND1 1 
ATOM   3383 C CD2 . HIS A 1 998  ? 215.910 198.912 208.045 1.00 43.99  ? 1009 HIS A CD2 1 
ATOM   3384 C CE1 . HIS A 1 998  ? 217.109 197.917 209.588 1.00 43.99  ? 1009 HIS A CE1 1 
ATOM   3385 N NE2 . HIS A 1 998  ? 216.904 199.071 208.980 1.00 43.99  ? 1009 HIS A NE2 1 
ATOM   3386 N N   . TYR A 1 999  ? 212.739 197.930 210.113 1.00 46.40  ? 1010 TYR A N   1 
ATOM   3387 C CA  . TYR A 1 999  ? 212.378 199.098 210.902 1.00 46.40  ? 1010 TYR A CA  1 
ATOM   3388 C C   . TYR A 1 999  ? 213.597 199.595 211.667 1.00 46.40  ? 1010 TYR A C   1 
ATOM   3389 O O   . TYR A 1 999  ? 214.348 198.799 212.239 1.00 46.40  ? 1010 TYR A O   1 
ATOM   3390 C CB  . TYR A 1 999  ? 211.243 198.780 211.879 1.00 46.40  ? 1010 TYR A CB  1 
ATOM   3391 C CG  . TYR A 1 999  ? 209.894 198.570 211.226 1.00 46.40  ? 1010 TYR A CG  1 
ATOM   3392 C CD1 . TYR A 1 999  ? 209.621 197.415 210.503 1.00 46.40  ? 1010 TYR A CD1 1 
ATOM   3393 C CD2 . TYR A 1 999  ? 208.892 199.524 211.337 1.00 46.40  ? 1010 TYR A CD2 1 
ATOM   3394 C CE1 . TYR A 1 999  ? 208.390 197.219 209.909 1.00 46.40  ? 1010 TYR A CE1 1 
ATOM   3395 C CE2 . TYR A 1 999  ? 207.657 199.335 210.746 1.00 46.40  ? 1010 TYR A CE2 1 
ATOM   3396 C CZ  . TYR A 1 999  ? 207.412 198.182 210.033 1.00 46.40  ? 1010 TYR A CZ  1 
ATOM   3397 O OH  . TYR A 1 999  ? 206.185 197.990 209.442 1.00 46.40  ? 1010 TYR A OH  1 
ATOM   3398 N N   . ASP A 1 1000 ? 213.792 200.915 211.667 1.00 52.10  ? 1011 ASP A N   1 
ATOM   3399 C CA  . ASP A 1 1000 ? 214.956 201.491 212.334 1.00 52.10  ? 1011 ASP A CA  1 
ATOM   3400 C C   . ASP A 1 1000 ? 214.905 201.271 213.841 1.00 52.10  ? 1011 ASP A C   1 
ATOM   3401 O O   . ASP A 1 1000 ? 215.918 200.917 214.456 1.00 52.10  ? 1011 ASP A O   1 
ATOM   3402 C CB  . ASP A 1 1000 ? 215.056 202.983 212.015 1.00 52.10  ? 1011 ASP A CB  1 
ATOM   3403 C CG  . ASP A 1 1000 ? 216.229 203.651 212.706 1.00 52.10  ? 1011 ASP A CG  1 
ATOM   3404 O OD1 . ASP A 1 1000 ? 217.261 202.980 212.913 1.00 52.10  ? 1011 ASP A OD1 1 
ATOM   3405 O OD2 . ASP A 1 1000 ? 216.118 204.848 213.041 1.00 52.10  ? 1011 ASP A OD2 1 
ATOM   3406 N N   . LYS A 1 1001 ? 213.741 201.471 214.454 1.00 54.71  ? 1012 LYS A N   1 
ATOM   3407 C CA  . LYS A 1 1001 ? 213.590 201.363 215.898 1.00 54.71  ? 1012 LYS A CA  1 
ATOM   3408 C C   . LYS A 1 1001 ? 212.414 200.458 216.231 1.00 54.71  ? 1012 LYS A C   1 
ATOM   3409 O O   . LYS A 1 1001 ? 211.380 200.493 215.557 1.00 54.71  ? 1012 LYS A O   1 
ATOM   3410 C CB  . LYS A 1 1001 ? 213.388 202.741 216.541 1.00 54.71  ? 1012 LYS A CB  1 
ATOM   3411 C CG  . LYS A 1 1001 ? 214.547 203.701 216.329 1.00 54.71  ? 1012 LYS A CG  1 
ATOM   3412 C CD  . LYS A 1 1001 ? 214.250 205.065 216.928 1.00 54.71  ? 1012 LYS A CD  1 
ATOM   3413 C CE  . LYS A 1 1001 ? 215.246 206.106 216.444 1.00 54.71  ? 1012 LYS A CE  1 
ATOM   3414 N NZ  . LYS A 1 1001 ? 214.815 207.489 216.787 1.00 54.71  ? 1012 LYS A NZ  1 
ATOM   3415 N N   . ASP A 1 1002 ? 212.579 199.650 217.276 1.00 54.76  ? 1013 ASP A N   1 
ATOM   3416 C CA  . ASP A 1 1002 ? 211.530 198.751 217.745 1.00 54.76  ? 1013 ASP A CA  1 
ATOM   3417 C C   . ASP A 1 1002 ? 210.650 199.505 218.735 1.00 54.76  ? 1013 ASP A C   1 
ATOM   3418 O O   . ASP A 1 1002 ? 211.091 199.838 219.841 1.00 54.76  ? 1013 ASP A O   1 
ATOM   3419 C CB  . ASP A 1 1002 ? 212.135 197.503 218.383 1.00 54.76  ? 1013 ASP A CB  1 
ATOM   3420 C CG  . ASP A 1 1002 ? 211.162 196.785 219.299 1.00 54.76  ? 1013 ASP A CG  1 
ATOM   3421 O OD1 . ASP A 1 1002 ? 210.029 196.496 218.858 1.00 54.76  ? 1013 ASP A OD1 1 
ATOM   3422 O OD2 . ASP A 1 1002 ? 211.529 196.511 220.460 1.00 54.76  ? 1013 ASP A OD2 1 
ATOM   3423 N N   . LEU A 1 1003 ? 209.408 199.777 218.339 1.00 52.31  ? 1014 LEU A N   1 
ATOM   3424 C CA  . LEU A 1 1003 ? 208.452 200.490 219.177 1.00 52.31  ? 1014 LEU A CA  1 
ATOM   3425 C C   . LEU A 1 1003 ? 207.208 199.649 219.445 1.00 52.31  ? 1014 LEU A C   1 
ATOM   3426 O O   . LEU A 1 1003 ? 206.098 200.178 219.529 1.00 52.31  ? 1014 LEU A O   1 
ATOM   3427 C CB  . LEU A 1 1003 ? 208.071 201.827 218.543 1.00 52.31  ? 1014 LEU A CB  1 
ATOM   3428 C CG  . LEU A 1 1003 ? 209.219 202.814 218.319 1.00 52.31  ? 1014 LEU A CG  1 
ATOM   3429 C CD1 . LEU A 1 1003 ? 208.694 204.137 217.787 1.00 52.31  ? 1014 LEU A CD1 1 
ATOM   3430 C CD2 . LEU A 1 1003 ? 210.002 203.023 219.605 1.00 52.31  ? 1014 LEU A CD2 1 
ATOM   3431 N N   . SER A 1 1004 ? 207.381 198.333 219.580 1.00 52.65  ? 1015 SER A N   1 
ATOM   3432 C CA  . SER A 1 1004 ? 206.244 197.453 219.825 1.00 52.65  ? 1015 SER A CA  1 
ATOM   3433 C C   . SER A 1 1004 ? 205.669 197.621 221.225 1.00 52.65  ? 1015 SER A C   1 
ATOM   3434 O O   . SER A 1 1004 ? 204.519 197.233 221.457 1.00 52.65  ? 1015 SER A O   1 
ATOM   3435 C CB  . SER A 1 1004 ? 206.648 195.996 219.601 1.00 52.65  ? 1015 SER A CB  1 
ATOM   3436 O OG  . SER A 1 1004 ? 205.821 195.118 220.345 1.00 52.65  ? 1015 SER A OG  1 
ATOM   3437 N N   . GLY A 1 1005 ? 206.435 198.183 222.157 1.00 54.55  ? 1016 GLY A N   1 
ATOM   3438 C CA  . GLY A 1 1005 ? 205.931 198.385 223.498 1.00 54.55  ? 1016 GLY A CA  1 
ATOM   3439 C C   . GLY A 1 1005 ? 204.852 199.448 223.555 1.00 54.55  ? 1016 GLY A C   1 
ATOM   3440 O O   . GLY A 1 1005 ? 204.763 200.340 222.712 1.00 54.55  ? 1016 GLY A O   1 
ATOM   3441 N N   . TYR A 1 1006 ? 204.009 199.342 224.580 1.00 54.20  ? 1017 TYR A N   1 
ATOM   3442 C CA  . TYR A 1 1006 ? 202.906 200.270 224.782 1.00 54.20  ? 1017 TYR A CA  1 
ATOM   3443 C C   . TYR A 1 1006 ? 203.211 201.327 225.835 1.00 54.20  ? 1017 TYR A C   1 
ATOM   3444 O O   . TYR A 1 1006 ? 202.307 202.068 226.234 1.00 54.20  ? 1017 TYR A O   1 
ATOM   3445 C CB  . TYR A 1 1006 ? 201.635 199.505 225.157 1.00 54.20  ? 1017 TYR A CB  1 
ATOM   3446 C CG  . TYR A 1 1006 ? 201.005 198.772 223.995 1.00 54.20  ? 1017 TYR A CG  1 
ATOM   3447 C CD1 . TYR A 1 1006 ? 201.479 197.531 223.592 1.00 54.20  ? 1017 TYR A CD1 1 
ATOM   3448 C CD2 . TYR A 1 1006 ? 199.940 199.324 223.298 1.00 54.20  ? 1017 TYR A CD2 1 
ATOM   3449 C CE1 . TYR A 1 1006 ? 200.907 196.859 222.529 1.00 54.20  ? 1017 TYR A CE1 1 
ATOM   3450 C CE2 . TYR A 1 1006 ? 199.362 198.660 222.234 1.00 54.20  ? 1017 TYR A CE2 1 
ATOM   3451 C CZ  . TYR A 1 1006 ? 199.849 197.428 221.854 1.00 54.20  ? 1017 TYR A CZ  1 
ATOM   3452 O OH  . TYR A 1 1006 ? 199.277 196.763 220.795 1.00 54.20  ? 1017 TYR A OH  1 
ATOM   3453 N N   . SER A 1 1007 ? 204.458 201.415 226.290 1.00 57.66  ? 1018 SER A N   1 
ATOM   3454 C CA  . SER A 1 1007 ? 204.831 202.420 227.271 1.00 57.66  ? 1018 SER A CA  1 
ATOM   3455 C C   . SER A 1 1007 ? 204.838 203.809 226.634 1.00 57.66  ? 1018 SER A C   1 
ATOM   3456 O O   . SER A 1 1007 ? 204.760 203.966 225.412 1.00 57.66  ? 1018 SER A O   1 
ATOM   3457 C CB  . SER A 1 1007 ? 206.201 202.103 227.868 1.00 57.66  ? 1018 SER A CB  1 
ATOM   3458 O OG  . SER A 1 1007 ? 207.150 201.842 226.850 1.00 57.66  ? 1018 SER A OG  1 
ATOM   3459 N N   . LEU A 1 1008 ? 204.925 204.827 227.488 1.00 58.25  ? 1019 LEU A N   1 
ATOM   3460 C CA  . LEU A 1 1008 ? 204.941 206.204 227.011 1.00 58.25  ? 1019 LEU A CA  1 
ATOM   3461 C C   . LEU A 1 1008 ? 206.169 206.451 226.145 1.00 58.25  ? 1019 LEU A C   1 
ATOM   3462 O O   . LEU A 1 1008 ? 207.283 206.051 226.495 1.00 58.25  ? 1019 LEU A O   1 
ATOM   3463 C CB  . LEU A 1 1008 ? 204.914 207.171 228.195 1.00 58.25  ? 1019 LEU A CB  1 
ATOM   3464 C CG  . LEU A 1 1008 ? 205.087 208.664 227.906 1.00 58.25  ? 1019 LEU A CG  1 
ATOM   3465 C CD1 . LEU A 1 1008 ? 204.107 209.476 228.735 1.00 58.25  ? 1019 LEU A CD1 1 
ATOM   3466 C CD2 . LEU A 1 1008 ? 206.513 209.112 228.189 1.00 58.25  ? 1019 LEU A CD2 1 
ATOM   3467 N N   . GLY A 1 1009 ? 205.961 207.113 225.009 1.00 56.84  ? 1020 GLY A N   1 
ATOM   3468 C CA  . GLY A 1 1009 ? 207.010 207.381 224.056 1.00 56.84  ? 1020 GLY A CA  1 
ATOM   3469 C C   . GLY A 1 1009 ? 207.103 206.379 222.924 1.00 56.84  ? 1020 GLY A C   1 
ATOM   3470 O O   . GLY A 1 1009 ? 207.808 206.639 221.942 1.00 56.84  ? 1020 GLY A O   1 
ATOM   3471 N N   . GLN A 1 1010 ? 206.415 205.248 223.032 1.00 55.03  ? 1021 GLN A N   1 
ATOM   3472 C CA  . GLN A 1 1010 ? 206.416 204.221 222.003 1.00 55.03  ? 1021 GLN A CA  1 
ATOM   3473 C C   . GLN A 1 1010 ? 205.065 204.175 221.296 1.00 55.03  ? 1021 GLN A C   1 
ATOM   3474 O O   . GLN A 1 1010 ? 204.028 204.534 221.859 1.00 55.03  ? 1021 GLN A O   1 
ATOM   3475 C CB  . GLN A 1 1010 ? 206.745 202.854 222.607 1.00 55.03  ? 1021 GLN A CB  1 
ATOM   3476 C CG  . GLN A 1 1010 ? 208.082 202.806 223.329 1.00 55.03  ? 1021 GLN A CG  1 
ATOM   3477 C CD  . GLN A 1 1010 ? 208.739 201.443 223.251 1.00 55.03  ? 1021 GLN A CD  1 
ATOM   3478 O OE1 . GLN A 1 1010 ? 208.292 200.567 222.513 1.00 55.03  ? 1021 GLN A OE1 1 
ATOM   3479 N NE2 . GLN A 1 1010 ? 209.808 201.258 224.017 1.00 55.03  ? 1021 GLN A NE2 1 
ATOM   3480 N N   . GLY A 1 1011 ? 205.093 203.723 220.045 1.00 52.53  ? 1022 GLY A N   1 
ATOM   3481 C CA  . GLY A 1 1011 ? 203.903 203.729 219.216 1.00 52.53  ? 1022 GLY A CA  1 
ATOM   3482 C C   . GLY A 1 1011 ? 203.026 202.504 219.366 1.00 52.53  ? 1022 GLY A C   1 
ATOM   3483 O O   . GLY A 1 1011 ? 201.866 202.511 218.944 1.00 52.53  ? 1022 GLY A O   1 
ATOM   3484 N N   . GLY A 1 1012 ? 203.564 201.448 219.967 1.00 50.41  ? 1023 GLY A N   1 
ATOM   3485 C CA  . GLY A 1 1012 ? 202.789 200.231 220.153 1.00 50.41  ? 1023 GLY A CA  1 
ATOM   3486 C C   . GLY A 1 1012 ? 202.399 199.543 218.864 1.00 50.41  ? 1023 GLY A C   1 
ATOM   3487 O O   . GLY A 1 1012 ? 201.261 199.074 218.732 1.00 50.41  ? 1023 GLY A O   1 
ATOM   3488 N N   . TYR A 1 1013 ? 203.317 199.474 217.904 1.00 50.05  ? 1024 TYR A N   1 
ATOM   3489 C CA  . TYR A 1 1013 ? 203.076 198.809 216.633 1.00 50.05  ? 1024 TYR A CA  1 
ATOM   3490 C C   . TYR A 1 1013 ? 204.230 197.866 216.327 1.00 50.05  ? 1024 TYR A C   1 
ATOM   3491 O O   . TYR A 1 1013 ? 205.373 198.108 216.726 1.00 50.05  ? 1024 TYR A O   1 
ATOM   3492 C CB  . TYR A 1 1013 ? 202.902 199.820 215.488 1.00 50.05  ? 1024 TYR A CB  1 
ATOM   3493 C CG  . TYR A 1 1013 ? 204.058 200.782 215.325 1.00 50.05  ? 1024 TYR A CG  1 
ATOM   3494 C CD1 . TYR A 1 1013 ? 204.068 202.003 215.986 1.00 50.05  ? 1024 TYR A CD1 1 
ATOM   3495 C CD2 . TYR A 1 1013 ? 205.135 200.474 214.504 1.00 50.05  ? 1024 TYR A CD2 1 
ATOM   3496 C CE1 . TYR A 1 1013 ? 205.120 202.887 215.839 1.00 50.05  ? 1024 TYR A CE1 1 
ATOM   3497 C CE2 . TYR A 1 1013 ? 206.191 201.351 214.351 1.00 50.05  ? 1024 TYR A CE2 1 
ATOM   3498 C CZ  . TYR A 1 1013 ? 206.178 202.555 215.021 1.00 50.05  ? 1024 TYR A CZ  1 
ATOM   3499 O OH  . TYR A 1 1013 ? 207.227 203.432 214.871 1.00 50.05  ? 1024 TYR A OH  1 
ATOM   3500 N N   . TYR A 1 1014 ? 203.918 196.783 215.616 1.00 51.66  ? 1025 TYR A N   1 
ATOM   3501 C CA  . TYR A 1 1014 ? 204.919 195.783 215.263 1.00 51.66  ? 1025 TYR A CA  1 
ATOM   3502 C C   . TYR A 1 1014 ? 205.992 196.389 214.368 1.00 51.66  ? 1025 TYR A C   1 
ATOM   3503 O O   . TYR A 1 1014 ? 205.727 196.723 213.209 1.00 51.66  ? 1025 TYR A O   1 
ATOM   3504 C CB  . TYR A 1 1014 ? 204.258 194.589 214.573 1.00 51.66  ? 1025 TYR A CB  1 
ATOM   3505 C CG  . TYR A 1 1014 ? 205.184 193.416 214.348 1.00 51.66  ? 1025 TYR A CG  1 
ATOM   3506 C CD1 . TYR A 1 1014 ? 205.874 192.839 215.405 1.00 51.66  ? 1025 TYR A CD1 1 
ATOM   3507 C CD2 . TYR A 1 1014 ? 205.363 192.882 213.079 1.00 51.66  ? 1025 TYR A CD2 1 
ATOM   3508 C CE1 . TYR A 1 1014 ? 206.720 191.765 215.204 1.00 51.66  ? 1025 TYR A CE1 1 
ATOM   3509 C CE2 . TYR A 1 1014 ? 206.207 191.808 212.868 1.00 51.66  ? 1025 TYR A CE2 1 
ATOM   3510 C CZ  . TYR A 1 1014 ? 206.883 191.254 213.934 1.00 51.66  ? 1025 TYR A CZ  1 
ATOM   3511 O OH  . TYR A 1 1014 ? 207.724 190.185 213.730 1.00 51.66  ? 1025 TYR A OH  1 
ATOM   3512 N N   . SER A 1 1015 ? 207.207 196.534 214.897 1.00 50.68  ? 1026 SER A N   1 
ATOM   3513 C CA  . SER A 1 1015 ? 208.323 197.150 214.180 1.00 50.68  ? 1026 SER A CA  1 
ATOM   3514 C C   . SER A 1 1015 ? 209.547 196.252 214.291 1.00 50.68  ? 1026 SER A C   1 
ATOM   3515 O O   . SER A 1 1015 ? 210.482 196.548 215.048 1.00 50.68  ? 1026 SER A O   1 
ATOM   3516 C CB  . SER A 1 1015 ? 208.618 198.549 214.721 1.00 50.68  ? 1026 SER A CB  1 
ATOM   3517 O OG  . SER A 1 1015 ? 208.549 198.571 216.136 1.00 50.68  ? 1026 SER A OG  1 
ATOM   3518 N N   . PRO A 1 1016 ? 209.578 195.144 213.553 1.00 47.12  ? 1027 PRO A N   1 
ATOM   3519 C CA  . PRO A 1 1016 ? 210.755 194.270 213.598 1.00 47.12  ? 1027 PRO A CA  1 
ATOM   3520 C C   . PRO A 1 1016 ? 211.934 194.894 212.868 1.00 47.12  ? 1027 PRO A C   1 
ATOM   3521 O O   . PRO A 1 1016 ? 211.783 195.487 211.798 1.00 47.12  ? 1027 PRO A O   1 
ATOM   3522 C CB  . PRO A 1 1016 ? 210.273 192.996 212.898 1.00 47.12  ? 1027 PRO A CB  1 
ATOM   3523 C CG  . PRO A 1 1016 ? 209.237 193.481 211.943 1.00 47.12  ? 1027 PRO A CG  1 
ATOM   3524 C CD  . PRO A 1 1016 ? 208.548 194.635 212.629 1.00 47.12  ? 1027 PRO A CD  1 
ATOM   3525 N N   . GLN A 1 1017 ? 213.120 194.756 213.464 1.00 48.61  ? 1028 GLN A N   1 
ATOM   3526 C CA  . GLN A 1 1017 ? 214.325 195.283 212.832 1.00 48.61  ? 1028 GLN A CA  1 
ATOM   3527 C C   . GLN A 1 1017 ? 214.648 194.531 211.547 1.00 48.61  ? 1028 GLN A C   1 
ATOM   3528 O O   . GLN A 1 1017 ? 215.070 195.138 210.556 1.00 48.61  ? 1028 GLN A O   1 
ATOM   3529 C CB  . GLN A 1 1017 ? 215.501 195.219 213.805 1.00 48.61  ? 1028 GLN A CB  1 
ATOM   3530 C CG  . GLN A 1 1017 ? 215.214 195.842 215.159 1.00 48.61  ? 1028 GLN A CG  1 
ATOM   3531 C CD  . GLN A 1 1017 ? 214.943 197.330 215.068 1.00 48.61  ? 1028 GLN A CD  1 
ATOM   3532 O OE1 . GLN A 1 1017 ? 214.029 197.847 215.710 1.00 48.61  ? 1028 GLN A OE1 1 
ATOM   3533 N NE2 . GLN A 1 1017 ? 215.738 198.029 214.267 1.00 48.61  ? 1028 GLN A NE2 1 
ATOM   3534 N N   . GLU A 1 1018 ? 214.460 193.213 211.544 1.00 51.87  ? 1029 GLU A N   1 
ATOM   3535 C CA  . GLU A 1 1018 ? 214.695 192.392 210.362 1.00 51.87  ? 1029 GLU A CA  1 
ATOM   3536 C C   . GLU A 1 1018 ? 213.582 191.361 210.262 1.00 51.87  ? 1029 GLU A C   1 
ATOM   3537 O O   . GLU A 1 1018 ? 213.385 190.568 211.187 1.00 51.87  ? 1029 GLU A O   1 
ATOM   3538 C CB  . GLU A 1 1018 ? 216.063 191.706 210.425 1.00 51.87  ? 1029 GLU A CB  1 
ATOM   3539 C CG  . GLU A 1 1018 ? 216.254 190.612 209.390 1.00 51.87  ? 1029 GLU A CG  1 
ATOM   3540 C CD  . GLU A 1 1018 ? 217.421 189.701 209.716 1.00 51.87  ? 1029 GLU A CD  1 
ATOM   3541 O OE1 . GLU A 1 1018 ? 217.989 189.833 210.821 1.00 51.87  ? 1029 GLU A OE1 1 
ATOM   3542 O OE2 . GLU A 1 1018 ? 217.769 188.852 208.869 1.00 51.87  ? 1029 GLU A OE2 1 
ATOM   3543 N N   . TYR A 1 1019 ? 212.860 191.373 209.145 1.00 44.19  ? 1030 TYR A N   1 
ATOM   3544 C CA  . TYR A 1 1019 ? 211.737 190.474 208.925 1.00 44.19  ? 1030 TYR A CA  1 
ATOM   3545 C C   . TYR A 1 1019 ? 211.911 189.757 207.596 1.00 44.19  ? 1030 TYR A C   1 
ATOM   3546 O O   . TYR A 1 1019 ? 212.421 190.335 206.631 1.00 44.19  ? 1030 TYR A O   1 
ATOM   3547 C CB  . TYR A 1 1019 ? 210.408 191.238 208.942 1.00 44.19  ? 1030 TYR A CB  1 
ATOM   3548 C CG  . TYR A 1 1019 ? 209.185 190.357 208.829 1.00 44.19  ? 1030 TYR A CG  1 
ATOM   3549 C CD1 . TYR A 1 1019 ? 208.784 189.554 209.888 1.00 44.19  ? 1030 TYR A CD1 1 
ATOM   3550 C CD2 . TYR A 1 1019 ? 208.429 190.332 207.666 1.00 44.19  ? 1030 TYR A CD2 1 
ATOM   3551 C CE1 . TYR A 1 1019 ? 207.665 188.749 209.790 1.00 44.19  ? 1030 TYR A CE1 1 
ATOM   3552 C CE2 . TYR A 1 1019 ? 207.308 189.532 207.559 1.00 44.19  ? 1030 TYR A CE2 1 
ATOM   3553 C CZ  . TYR A 1 1019 ? 206.932 188.742 208.624 1.00 44.19  ? 1030 TYR A CZ  1 
ATOM   3554 O OH  . TYR A 1 1019 ? 205.817 187.942 208.521 1.00 44.19  ? 1030 TYR A OH  1 
ATOM   3555 N N   . LEU A 1 1020 ? 211.486 188.497 207.550 1.00 46.81  ? 1031 LEU A N   1 
ATOM   3556 C CA  . LEU A 1 1020 ? 211.580 187.694 206.336 1.00 46.81  ? 1031 LEU A CA  1 
ATOM   3557 C C   . LEU A 1 1020 ? 210.493 186.633 206.378 1.00 46.81  ? 1031 LEU A C   1 
ATOM   3558 O O   . LEU A 1 1020 ? 210.468 185.811 207.299 1.00 46.81  ? 1031 LEU A O   1 
ATOM   3559 C CB  . LEU A 1 1020 ? 212.960 187.048 206.207 1.00 46.81  ? 1031 LEU A CB  1 
ATOM   3560 C CG  . LEU A 1 1020 ? 213.119 186.017 205.090 1.00 46.81  ? 1031 LEU A CG  1 
ATOM   3561 C CD1 . LEU A 1 1020 ? 212.923 186.667 203.730 1.00 46.81  ? 1031 LEU A CD1 1 
ATOM   3562 C CD2 . LEU A 1 1020 ? 214.477 185.339 205.174 1.00 46.81  ? 1031 LEU A CD2 1 
ATOM   3563 N N   . SER A 1 1021 ? 209.604 186.647 205.388 1.00 47.60  ? 1032 SER A N   1 
ATOM   3564 C CA  . SER A 1 1021 ? 208.466 185.739 205.352 1.00 47.60  ? 1032 SER A CA  1 
ATOM   3565 C C   . SER A 1 1021 ? 208.352 185.103 203.976 1.00 47.60  ? 1032 SER A C   1 
ATOM   3566 O O   . SER A 1 1021 ? 208.474 185.792 202.958 1.00 47.60  ? 1032 SER A O   1 
ATOM   3567 C CB  . SER A 1 1021 ? 207.166 186.471 205.701 1.00 47.60  ? 1032 SER A CB  1 
ATOM   3568 O OG  . SER A 1 1021 ? 206.054 185.596 205.631 1.00 47.60  ? 1032 SER A OG  1 
ATOM   3569 N N   . PHE A 1 1022 ? 208.120 183.793 203.951 1.00 50.56  ? 1033 PHE A N   1 
ATOM   3570 C CA  . PHE A 1 1022 ? 207.843 183.052 202.726 1.00 50.56  ? 1033 PHE A CA  1 
ATOM   3571 C C   . PHE A 1 1022 ? 206.476 182.402 202.866 1.00 50.56  ? 1033 PHE A C   1 
ATOM   3572 O O   . PHE A 1 1022 ? 206.240 181.647 203.815 1.00 50.56  ? 1033 PHE A O   1 
ATOM   3573 C CB  . PHE A 1 1022 ? 208.917 181.996 202.458 1.00 50.56  ? 1033 PHE A CB  1 
ATOM   3574 C CG  . PHE A 1 1022 ? 210.283 182.566 202.208 1.00 50.56  ? 1033 PHE A CG  1 
ATOM   3575 C CD1 . PHE A 1 1022 ? 210.633 183.035 200.953 1.00 50.56  ? 1033 PHE A CD1 1 
ATOM   3576 C CD2 . PHE A 1 1022 ? 211.221 182.625 203.225 1.00 50.56  ? 1033 PHE A CD2 1 
ATOM   3577 C CE1 . PHE A 1 1022 ? 211.891 183.558 200.719 1.00 50.56  ? 1033 PHE A CE1 1 
ATOM   3578 C CE2 . PHE A 1 1022 ? 212.480 183.146 202.997 1.00 50.56  ? 1033 PHE A CE2 1 
ATOM   3579 C CZ  . PHE A 1 1022 ? 212.815 183.613 201.742 1.00 50.56  ? 1033 PHE A CZ  1 
ATOM   3580 N N   . ALA A 1 1023 ? 205.582 182.687 201.924 1.00 56.71  ? 1034 ALA A N   1 
ATOM   3581 C CA  . ALA A 1 1023 ? 204.215 182.192 201.967 1.00 56.71  ? 1034 ALA A CA  1 
ATOM   3582 C C   . ALA A 1 1023 ? 203.864 181.495 200.661 1.00 56.71  ? 1034 ALA A C   1 
ATOM   3583 O O   . ALA A 1 1023 ? 204.368 181.849 199.592 1.00 56.71  ? 1034 ALA A O   1 
ATOM   3584 C CB  . ALA A 1 1023 ? 203.221 183.329 202.232 1.00 56.71  ? 1034 ALA A CB  1 
ATOM   3585 N N   . ILE A 1 1024 ? 202.987 180.500 200.759 1.00 60.25  ? 1035 ILE A N   1 
ATOM   3586 C CA  . ILE A 1 1024 ? 202.529 179.744 199.596 1.00 60.25  ? 1035 ILE A CA  1 
ATOM   3587 C C   . ILE A 1 1024 ? 201.013 179.872 199.505 1.00 60.25  ? 1035 ILE A C   1 
ATOM   3588 O O   . ILE A 1 1024 ? 200.285 179.031 200.051 1.00 60.25  ? 1035 ILE A O   1 
ATOM   3589 C CB  . ILE A 1 1024 ? 202.960 178.272 199.680 1.00 60.25  ? 1035 ILE A CB  1 
ATOM   3590 C CG1 . ILE A 1 1024 ? 204.451 178.167 200.006 1.00 60.25  ? 1035 ILE A CG1 1 
ATOM   3591 C CG2 . ILE A 1 1024 ? 202.649 177.549 198.378 1.00 60.25  ? 1035 ILE A CG2 1 
ATOM   3592 C CD1 . ILE A 1 1024 ? 204.941 176.745 200.169 1.00 60.25  ? 1035 ILE A CD1 1 
ATOM   3593 N N   . PRO A 1 1025 ? 200.493 180.901 198.833 1.00 66.23  ? 1036 PRO A N   1 
ATOM   3594 C CA  . PRO A 1 1025 ? 199.038 181.084 198.774 1.00 66.23  ? 1036 PRO A CA  1 
ATOM   3595 C C   . PRO A 1 1025 ? 198.378 180.289 197.660 1.00 66.23  ? 1036 PRO A C   1 
ATOM   3596 O O   . PRO A 1 1025 ? 198.900 180.213 196.543 1.00 66.23  ? 1036 PRO A O   1 
ATOM   3597 C CB  . PRO A 1 1025 ? 198.893 182.592 198.547 1.00 66.23  ? 1036 PRO A CB  1 
ATOM   3598 C CG  . PRO A 1 1025 ? 200.121 182.966 197.777 1.00 66.23  ? 1036 PRO A CG  1 
ATOM   3599 C CD  . PRO A 1 1025 ? 201.218 181.993 198.158 1.00 66.23  ? 1036 PRO A CD  1 
ATOM   3600 N N   . VAL A 1 1026 ? 197.229 179.690 197.959 1.00 69.09  ? 1037 VAL A N   1 
ATOM   3601 C CA  . VAL A 1 1026 ? 196.410 178.993 196.974 1.00 69.09  ? 1037 VAL A CA  1 
ATOM   3602 C C   . VAL A 1 1026 ? 195.061 179.694 196.901 1.00 69.09  ? 1037 VAL A C   1 
ATOM   3603 O O   . VAL A 1 1026 ? 194.405 179.905 197.929 1.00 69.09  ? 1037 VAL A O   1 
ATOM   3604 C CB  . VAL A 1 1026 ? 196.254 177.500 197.318 1.00 69.09  ? 1037 VAL A CB  1 
ATOM   3605 C CG1 . VAL A 1 1026 ? 195.892 177.315 198.785 1.00 69.09  ? 1037 VAL A CG1 1 
ATOM   3606 C CG2 . VAL A 1 1026 ? 195.210 176.854 196.420 1.00 69.09  ? 1037 VAL A CG2 1 
ATOM   3607 N N   . MET A 1 1027 ? 194.654 180.065 195.691 1.00 78.89  ? 1038 MET A N   1 
ATOM   3608 C CA  . MET A 1 1027 ? 193.431 180.819 195.463 1.00 78.89  ? 1038 MET A CA  1 
ATOM   3609 C C   . MET A 1 1027 ? 192.433 179.973 194.683 1.00 78.89  ? 1038 MET A C   1 
ATOM   3610 O O   . MET A 1 1027 ? 192.786 178.982 194.039 1.00 78.89  ? 1038 MET A O   1 
ATOM   3611 C CB  . MET A 1 1027 ? 193.722 182.121 194.704 1.00 78.89  ? 1038 MET A CB  1 
ATOM   3612 C CG  . MET A 1 1027 ? 193.833 183.388 195.557 1.00 78.89  ? 1038 MET A CG  1 
ATOM   3613 S SD  . MET A 1 1027 ? 192.513 183.654 196.762 1.00 78.89  ? 1038 MET A SD  1 
ATOM   3614 C CE  . MET A 1 1027 ? 193.218 182.941 198.248 1.00 78.89  ? 1038 MET A CE  1 
ATOM   3615 N N   . TRP A 1 1028 ? 191.167 180.381 194.750 1.00 76.29  ? 1039 TRP A N   1 
ATOM   3616 C CA  . TRP A 1 1028 ? 190.114 179.728 193.975 1.00 76.29  ? 1039 TRP A CA  1 
ATOM   3617 C C   . TRP A 1 1028 ? 189.024 180.760 193.723 1.00 76.29  ? 1039 TRP A C   1 
ATOM   3618 O O   . TRP A 1 1028 ? 188.244 181.069 194.629 1.00 76.29  ? 1039 TRP A O   1 
ATOM   3619 C CB  . TRP A 1 1028 ? 189.564 178.510 194.709 1.00 76.29  ? 1039 TRP A CB  1 
ATOM   3620 C CG  . TRP A 1 1028 ? 188.398 177.865 194.015 1.00 76.29  ? 1039 TRP A CG  1 
ATOM   3621 C CD1 . TRP A 1 1028 ? 188.130 177.880 192.677 1.00 76.29  ? 1039 TRP A CD1 1 
ATOM   3622 C CD2 . TRP A 1 1028 ? 187.344 177.110 194.625 1.00 76.29  ? 1039 TRP A CD2 1 
ATOM   3623 N NE1 . TRP A 1 1028 ? 186.976 177.183 192.416 1.00 76.29  ? 1039 TRP A NE1 1 
ATOM   3624 C CE2 . TRP A 1 1028 ? 186.474 176.700 193.595 1.00 76.29  ? 1039 TRP A CE2 1 
ATOM   3625 C CE3 . TRP A 1 1028 ? 187.052 176.741 195.941 1.00 76.29  ? 1039 TRP A CE3 1 
ATOM   3626 C CZ2 . TRP A 1 1028 ? 185.333 175.940 193.840 1.00 76.29  ? 1039 TRP A CZ2 1 
ATOM   3627 C CZ3 . TRP A 1 1028 ? 185.918 175.986 196.182 1.00 76.29  ? 1039 TRP A CZ3 1 
ATOM   3628 C CH2 . TRP A 1 1028 ? 185.073 175.594 195.137 1.00 76.29  ? 1039 TRP A CH2 1 
ATOM   3629 N N   . ARG A 1 1029 ? 188.972 181.284 192.503 1.00 77.56  ? 1040 ARG A N   1 
ATOM   3630 C CA  . ARG A 1 1029 ? 187.990 182.284 192.111 1.00 77.56  ? 1040 ARG A CA  1 
ATOM   3631 C C   . ARG A 1 1029 ? 187.032 181.673 191.098 1.00 77.56  ? 1040 ARG A C   1 
ATOM   3632 O O   . ARG A 1 1029 ? 187.465 181.143 190.070 1.00 77.56  ? 1040 ARG A O   1 
ATOM   3633 C CB  . ARG A 1 1029 ? 188.674 183.519 191.521 1.00 77.56  ? 1040 ARG A CB  1 
ATOM   3634 C CG  . ARG A 1 1029 ? 189.431 184.352 192.543 1.00 77.56  ? 1040 ARG A CG  1 
ATOM   3635 C CD  . ARG A 1 1029 ? 189.682 185.763 192.035 1.00 77.56  ? 1040 ARG A CD  1 
ATOM   3636 N NE  . ARG A 1 1029 ? 190.670 185.797 190.963 1.00 77.56  ? 1040 ARG A NE  1 
ATOM   3637 C CZ  . ARG A 1 1029 ? 191.980 185.695 191.147 1.00 77.56  ? 1040 ARG A CZ  1 
ATOM   3638 N NH1 . ARG A 1 1029 ? 192.500 185.558 192.355 1.00 77.56  ? 1040 ARG A NH1 1 
ATOM   3639 N NH2 . ARG A 1 1029 ? 192.788 185.736 190.091 1.00 77.56  ? 1040 ARG A NH2 1 
ATOM   3640 N N   . GLU A 1 1030 ? 185.736 181.750 191.391 1.00 78.04  ? 1041 GLU A N   1 
ATOM   3641 C CA  . GLU A 1 1030 ? 184.720 181.196 190.510 1.00 78.04  ? 1041 GLU A CA  1 
ATOM   3642 C C   . GLU A 1 1030 ? 183.457 182.034 190.628 1.00 78.04  ? 1041 GLU A C   1 
ATOM   3643 O O   . GLU A 1 1030 ? 183.235 182.722 191.628 1.00 78.04  ? 1041 GLU A O   1 
ATOM   3644 C CB  . GLU A 1 1030 ? 184.425 179.727 190.841 1.00 78.04  ? 1041 GLU A CB  1 
ATOM   3645 C CG  . GLU A 1 1030 ? 183.785 178.949 189.702 1.00 78.04  ? 1041 GLU A CG  1 
ATOM   3646 C CD  . GLU A 1 1030 ? 183.600 177.481 190.030 1.00 78.04  ? 1041 GLU A CD  1 
ATOM   3647 O OE1 . GLU A 1 1030 ? 184.013 177.059 191.130 1.00 78.04  ? 1041 GLU A OE1 1 
ATOM   3648 O OE2 . GLU A 1 1030 ? 183.040 176.750 189.187 1.00 78.04  ? 1041 GLU A OE2 1 
ATOM   3649 N N   . ARG A 1 1031 ? 182.658 181.997 189.562 1.00 77.81  ? 1042 ARG A N   1 
ATOM   3650 C CA  . ARG A 1 1031 ? 181.396 182.771 189.550 1.00 77.81  ? 1042 ARG A CA  1 
ATOM   3651 C C   . ARG A 1 1031 ? 180.375 182.059 188.664 1.00 77.81  ? 1042 ARG A C   1 
ATOM   3652 O O   . ARG A 1 1031 ? 180.787 181.273 187.785 1.00 77.81  ? 1042 ARG A O   1 
ATOM   3653 C CB  . ARG A 1 1031 ? 181.595 184.186 189.000 1.00 77.81  ? 1042 ARG A CB  1 
ATOM   3654 C CG  . ARG A 1 1031 ? 181.889 184.234 187.508 1.00 77.81  ? 1042 ARG A CG  1 
ATOM   3655 C CD  . ARG A 1 1031 ? 182.030 185.657 187.001 1.00 77.81  ? 1042 ARG A CD  1 
ATOM   3656 N NE  . ARG A 1 1031 ? 182.603 185.684 185.652 1.00 77.81  ? 1042 ARG A NE  1 
ATOM   3657 C CZ  . ARG A 1 1031 ? 182.919 186.788 184.991 1.00 77.81  ? 1042 ARG A CZ  1 
ATOM   3658 N NH1 . ARG A 1 1031 ? 182.885 187.957 185.603 1.00 77.81  ? 1042 ARG A NH1 1 
ATOM   3659 N NH2 . ARG A 1 1031 ? 183.279 186.716 183.722 1.00 77.81  ? 1042 ARG A NH2 1 
ATOM   3660 N N   . THR A 1 1032 ? 179.097 182.312 188.906 1.00 77.98  ? 1043 THR A N   1 
ATOM   3661 C CA  . THR A 1 1032 ? 178.009 181.750 188.116 1.00 77.98  ? 1043 THR A CA  1 
ATOM   3662 C C   . THR A 1 1032 ? 176.966 182.827 187.847 1.00 77.98  ? 1043 THR A C   1 
ATOM   3663 O O   . THR A 1 1032 ? 177.255 184.020 187.984 1.00 77.98  ? 1043 THR A O   1 
ATOM   3664 C CB  . THR A 1 1032 ? 177.385 180.541 188.818 1.00 77.98  ? 1043 THR A CB  1 
ATOM   3665 O OG1 . THR A 1 1032 ? 176.355 179.984 187.991 1.00 77.98  ? 1043 THR A OG1 1 
ATOM   3666 C CG2 . THR A 1 1032 ? 176.794 180.941 190.155 1.00 77.98  ? 1043 THR A CG2 1 
ATOM   3667 N N   . GLU A 1 1033 ? 175.760 182.418 187.445 1.00 81.88  ? 1044 GLU A N   1 
ATOM   3668 C CA  . GLU A 1 1033 ? 174.728 183.383 187.078 1.00 81.88  ? 1044 GLU A CA  1 
ATOM   3669 C C   . GLU A 1 1033 ? 174.401 184.331 188.228 1.00 81.88  ? 1044 GLU A C   1 
ATOM   3670 O O   . GLU A 1 1033 ? 174.244 185.539 188.019 1.00 81.88  ? 1044 GLU A O   1 
ATOM   3671 C CB  . GLU A 1 1033 ? 173.467 182.650 186.618 1.00 81.88  ? 1044 GLU A CB  1 
ATOM   3672 C CG  . GLU A 1 1033 ? 172.364 183.567 186.116 1.00 81.88  ? 1044 GLU A CG  1 
ATOM   3673 C CD  . GLU A 1 1033 ? 171.059 182.834 185.876 1.00 81.88  ? 1044 GLU A CD  1 
ATOM   3674 O OE1 . GLU A 1 1033 ? 171.001 181.617 186.150 1.00 81.88  ? 1044 GLU A OE1 1 
ATOM   3675 O OE2 . GLU A 1 1033 ? 170.092 183.474 185.414 1.00 81.88  ? 1044 GLU A OE2 1 
ATOM   3676 N N   . ASN A 1 1034 ? 174.298 183.806 189.451 1.00 76.37  ? 1045 ASN A N   1 
ATOM   3677 C CA  . ASN A 1 1034 ? 173.897 184.612 190.595 1.00 76.37  ? 1045 ASN A CA  1 
ATOM   3678 C C   . ASN A 1 1034 ? 174.875 184.589 191.762 1.00 76.37  ? 1045 ASN A C   1 
ATOM   3679 O O   . ASN A 1 1034 ? 174.748 185.428 192.661 1.00 76.37  ? 1045 ASN A O   1 
ATOM   3680 C CB  . ASN A 1 1034 ? 172.517 184.167 191.105 1.00 76.37  ? 1045 ASN A CB  1 
ATOM   3681 C CG  . ASN A 1 1034 ? 171.389 184.604 190.192 1.00 76.37  ? 1045 ASN A CG  1 
ATOM   3682 O OD1 . ASN A 1 1034 ? 171.619 185.218 189.150 1.00 76.37  ? 1045 ASN A OD1 1 
ATOM   3683 N ND2 . ASN A 1 1034 ? 170.158 184.290 190.581 1.00 76.37  ? 1045 ASN A ND2 1 
ATOM   3684 N N   . TRP A 1 1035 ? 175.838 183.673 191.783 1.00 75.48  ? 1046 TRP A N   1 
ATOM   3685 C CA  . TRP A 1 1035 ? 176.756 183.531 192.903 1.00 75.48  ? 1046 TRP A CA  1 
ATOM   3686 C C   . TRP A 1 1035 ? 178.183 183.852 192.477 1.00 75.48  ? 1046 TRP A C   1 
ATOM   3687 O O   . TRP A 1 1035 ? 178.585 183.595 191.339 1.00 75.48  ? 1046 TRP A O   1 
ATOM   3688 C CB  . TRP A 1 1035 ? 176.703 182.115 193.485 1.00 75.48  ? 1046 TRP A CB  1 
ATOM   3689 C CG  . TRP A 1 1035 ? 175.405 181.773 194.146 1.00 75.48  ? 1046 TRP A CG  1 
ATOM   3690 C CD1 . TRP A 1 1035 ? 174.354 181.104 193.590 1.00 75.48  ? 1046 TRP A CD1 1 
ATOM   3691 C CD2 . TRP A 1 1035 ? 175.026 182.068 195.495 1.00 75.48  ? 1046 TRP A CD2 1 
ATOM   3692 N NE1 . TRP A 1 1035 ? 173.340 180.972 194.507 1.00 75.48  ? 1046 TRP A NE1 1 
ATOM   3693 C CE2 . TRP A 1 1035 ? 173.727 181.554 195.684 1.00 75.48  ? 1046 TRP A CE2 1 
ATOM   3694 C CE3 . TRP A 1 1035 ? 175.655 182.719 196.559 1.00 75.48  ? 1046 TRP A CE3 1 
ATOM   3695 C CZ2 . TRP A 1 1035 ? 173.048 181.672 196.895 1.00 75.48  ? 1046 TRP A CZ2 1 
ATOM   3696 C CZ3 . TRP A 1 1035 ? 174.979 182.835 197.760 1.00 75.48  ? 1046 TRP A CZ3 1 
ATOM   3697 C CH2 . TRP A 1 1035 ? 173.690 182.313 197.918 1.00 75.48  ? 1046 TRP A CH2 1 
ATOM   3698 N N   . SER A 1 1036 ? 178.944 184.420 193.410 1.00 75.16  ? 1047 SER A N   1 
ATOM   3699 C CA  . SER A 1 1036 ? 180.360 184.704 193.197 1.00 75.16  ? 1047 SER A CA  1 
ATOM   3700 C C   . SER A 1 1036 ? 181.081 184.515 194.521 1.00 75.16  ? 1047 SER A C   1 
ATOM   3701 O O   . SER A 1 1036 ? 180.796 185.229 195.487 1.00 75.16  ? 1047 SER A O   1 
ATOM   3702 C CB  . SER A 1 1036 ? 180.567 186.122 192.662 1.00 75.16  ? 1047 SER A CB  1 
ATOM   3703 O OG  . SER A 1 1036 ? 181.946 186.417 192.526 1.00 75.16  ? 1047 SER A OG  1 
ATOM   3704 N N   . TRP A 1 1037 ? 182.009 183.561 194.567 1.00 75.41  ? 1048 TRP A N   1 
ATOM   3705 C CA  . TRP A 1 1037 ? 182.679 183.198 195.806 1.00 75.41  ? 1048 TRP A CA  1 
ATOM   3706 C C   . TRP A 1 1037 ? 184.172 183.041 195.559 1.00 75.41  ? 1048 TRP A C   1 
ATOM   3707 O O   . TRP A 1 1037 ? 184.616 182.809 194.432 1.00 75.41  ? 1048 TRP A O   1 
ATOM   3708 C CB  . TRP A 1 1037 ? 182.105 181.903 196.395 1.00 75.41  ? 1048 TRP A CB  1 
ATOM   3709 C CG  . TRP A 1 1037 ? 182.315 180.706 195.518 1.00 75.41  ? 1048 TRP A CG  1 
ATOM   3710 C CD1 . TRP A 1 1037 ? 183.399 179.878 195.508 1.00 75.41  ? 1048 TRP A CD1 1 
ATOM   3711 C CD2 . TRP A 1 1037 ? 181.422 180.210 194.514 1.00 75.41  ? 1048 TRP A CD2 1 
ATOM   3712 N NE1 . TRP A 1 1037 ? 183.234 178.894 194.564 1.00 75.41  ? 1048 TRP A NE1 1 
ATOM   3713 C CE2 . TRP A 1 1037 ? 182.029 179.076 193.939 1.00 75.41  ? 1048 TRP A CE2 1 
ATOM   3714 C CE3 . TRP A 1 1037 ? 180.168 180.613 194.047 1.00 75.41  ? 1048 TRP A CE3 1 
ATOM   3715 C CZ2 . TRP A 1 1037 ? 181.425 178.341 192.923 1.00 75.41  ? 1048 TRP A CZ2 1 
ATOM   3716 C CZ3 . TRP A 1 1037 ? 179.570 179.882 193.037 1.00 75.41  ? 1048 TRP A CZ3 1 
ATOM   3717 C CH2 . TRP A 1 1037 ? 180.198 178.759 192.486 1.00 75.41  ? 1048 TRP A CH2 1 
ATOM   3718 N N   . GLU A 1 1038 ? 184.944 183.172 196.636 1.00 78.51  ? 1049 GLU A N   1 
ATOM   3719 C CA  . GLU A 1 1038 ? 186.384 182.950 196.599 1.00 78.51  ? 1049 GLU A CA  1 
ATOM   3720 C C   . GLU A 1 1038 ? 186.815 182.280 197.894 1.00 78.51  ? 1049 GLU A C   1 
ATOM   3721 O O   . GLU A 1 1038 ? 186.509 182.776 198.982 1.00 78.51  ? 1049 GLU A O   1 
ATOM   3722 C CB  . GLU A 1 1038 ? 187.150 184.263 196.406 1.00 78.51  ? 1049 GLU A CB  1 
ATOM   3723 C CG  . GLU A 1 1038 ? 188.609 184.190 196.831 1.00 78.51  ? 1049 GLU A CG  1 
ATOM   3724 C CD  . GLU A 1 1038 ? 189.337 185.506 196.655 1.00 78.51  ? 1049 GLU A CD  1 
ATOM   3725 O OE1 . GLU A 1 1038 ? 189.098 186.188 195.637 1.00 78.51  ? 1049 GLU A OE1 1 
ATOM   3726 O OE2 . GLU A 1 1038 ? 190.149 185.861 197.536 1.00 78.51  ? 1049 GLU A OE2 1 
ATOM   3727 N N   . LEU A 1 1039 ? 187.522 181.158 197.774 1.00 77.70  ? 1050 LEU A N   1 
ATOM   3728 C CA  . LEU A 1 1039 ? 188.021 180.410 198.920 1.00 77.70  ? 1050 LEU A CA  1 
ATOM   3729 C C   . LEU A 1 1039 ? 189.505 180.144 198.727 1.00 77.70  ? 1050 LEU A C   1 
ATOM   3730 O O   . LEU A 1 1039 ? 189.945 179.860 197.609 1.00 77.70  ? 1050 LEU A O   1 
ATOM   3731 C CB  . LEU A 1 1039 ? 187.266 179.088 199.096 1.00 77.70  ? 1050 LEU A CB  1 
ATOM   3732 C CG  . LEU A 1 1039 ? 185.737 179.149 199.106 1.00 77.70  ? 1050 LEU A CG  1 
ATOM   3733 C CD1 . LEU A 1 1039 ? 185.150 177.753 199.236 1.00 77.70  ? 1050 LEU A CD1 1 
ATOM   3734 C CD2 . LEU A 1 1039 ? 185.241 180.045 200.228 1.00 77.70  ? 1050 LEU A CD2 1 
ATOM   3735 N N   . GLY A 1 1040 ? 190.274 180.239 199.809 1.00 76.97  ? 1051 GLY A N   1 
ATOM   3736 C CA  . GLY A 1 1040 ? 191.698 179.987 199.711 1.00 76.97  ? 1051 GLY A CA  1 
ATOM   3737 C C   . GLY A 1 1040 ? 192.365 179.991 201.069 1.00 76.97  ? 1051 GLY A C   1 
ATOM   3738 O O   . GLY A 1 1040 ? 191.736 180.238 202.100 1.00 76.97  ? 1051 GLY A O   1 
ATOM   3739 N N   . ALA A 1 1041 ? 193.666 179.709 201.048 1.00 70.12  ? 1052 ALA A N   1 
ATOM   3740 C CA  . ALA A 1 1041 ? 194.481 179.681 202.253 1.00 70.12  ? 1052 ALA A CA  1 
ATOM   3741 C C   . ALA A 1 1041 ? 195.923 179.966 201.862 1.00 70.12  ? 1052 ALA A C   1 
ATOM   3742 O O   . ALA A 1 1041 ? 196.287 179.906 200.685 1.00 70.12  ? 1052 ALA A O   1 
ATOM   3743 C CB  . ALA A 1 1041 ? 194.369 178.338 202.983 1.00 70.12  ? 1052 ALA A CB  1 
ATOM   3744 N N   . SER A 1 1042 ? 196.741 180.282 202.865 1.00 65.80  ? 1053 SER A N   1 
ATOM   3745 C CA  . SER A 1 1042 ? 198.141 180.619 202.612 1.00 65.80  ? 1053 SER A CA  1 
ATOM   3746 C C   . SER A 1 1042 ? 198.953 180.322 203.864 1.00 65.80  ? 1053 SER A C   1 
ATOM   3747 O O   . SER A 1 1042 ? 198.833 181.040 204.861 1.00 65.80  ? 1053 SER A O   1 
ATOM   3748 C CB  . SER A 1 1042 ? 198.277 182.081 202.205 1.00 65.80  ? 1053 SER A CB  1 
ATOM   3749 O OG  . SER A 1 1042 ? 199.586 182.361 201.741 1.00 65.80  ? 1053 SER A OG  1 
ATOM   3750 N N   . GLY A 1 1043 ? 199.775 179.276 203.809 1.00 60.70  ? 1054 GLY A N   1 
ATOM   3751 C CA  . GLY A 1 1043 ? 200.702 178.980 204.887 1.00 60.70  ? 1054 GLY A CA  1 
ATOM   3752 C C   . GLY A 1 1043 ? 202.007 179.737 204.696 1.00 60.70  ? 1054 GLY A C   1 
ATOM   3753 O O   . GLY A 1 1043 ? 202.543 179.810 203.592 1.00 60.70  ? 1054 GLY A O   1 
ATOM   3754 N N   . SER A 1 1044 ? 202.512 180.300 205.791 1.00 55.13  ? 1055 SER A N   1 
ATOM   3755 C CA  . SER A 1 1044 ? 203.675 181.172 205.741 1.00 55.13  ? 1055 SER A CA  1 
ATOM   3756 C C   . SER A 1 1044 ? 204.683 180.787 206.814 1.00 55.13  ? 1055 SER A C   1 
ATOM   3757 O O   . SER A 1 1044 ? 204.321 180.317 207.895 1.00 55.13  ? 1055 SER A O   1 
ATOM   3758 C CB  . SER A 1 1044 ? 203.275 182.644 205.917 1.00 55.13  ? 1055 SER A CB  1 
ATOM   3759 O OG  . SER A 1 1044 ? 202.762 182.879 207.216 1.00 55.13  ? 1055 SER A OG  1 
ATOM   3760 N N   . TRP A 1 1045 ? 205.959 180.995 206.495 1.00 49.01  ? 1056 TRP A N   1 
ATOM   3761 C CA  . TRP A 1 1045 ? 207.061 180.829 207.432 1.00 49.01  ? 1056 TRP A CA  1 
ATOM   3762 C C   . TRP A 1 1045 ? 207.766 182.168 207.584 1.00 49.01  ? 1056 TRP A C   1 
ATOM   3763 O O   . TRP A 1 1045 ? 208.195 182.761 206.589 1.00 49.01  ? 1056 TRP A O   1 
ATOM   3764 C CB  . TRP A 1 1045 ? 208.042 179.758 206.946 1.00 49.01  ? 1056 TRP A CB  1 
ATOM   3765 C CG  . TRP A 1 1045 ? 209.248 179.594 207.820 1.00 49.01  ? 1056 TRP A CG  1 
ATOM   3766 C CD1 . TRP A 1 1045 ? 209.364 178.786 208.912 1.00 49.01  ? 1056 TRP A CD1 1 
ATOM   3767 C CD2 . TRP A 1 1045 ? 210.512 180.251 207.670 1.00 49.01  ? 1056 TRP A CD2 1 
ATOM   3768 N NE1 . TRP A 1 1045 ? 210.621 178.901 209.455 1.00 49.01  ? 1056 TRP A NE1 1 
ATOM   3769 C CE2 . TRP A 1 1045 ? 211.346 179.794 208.710 1.00 49.01  ? 1056 TRP A CE2 1 
ATOM   3770 C CE3 . TRP A 1 1045 ? 211.020 181.181 206.759 1.00 49.01  ? 1056 TRP A CE3 1 
ATOM   3771 C CZ2 . TRP A 1 1045 ? 212.658 180.236 208.864 1.00 49.01  ? 1056 TRP A CZ2 1 
ATOM   3772 C CZ3 . TRP A 1 1045 ? 212.323 181.619 206.914 1.00 49.01  ? 1056 TRP A CZ3 1 
ATOM   3773 C CH2 . TRP A 1 1045 ? 213.127 181.146 207.958 1.00 49.01  ? 1056 TRP A CH2 1 
ATOM   3774 N N   . SER A 1 1046 ? 207.888 182.640 208.822 1.00 47.77  ? 1057 SER A N   1 
ATOM   3775 C CA  . SER A 1 1046 ? 208.421 183.967 209.089 1.00 47.77  ? 1057 SER A CA  1 
ATOM   3776 C C   . SER A 1 1046 ? 209.536 183.893 210.121 1.00 47.77  ? 1057 SER A C   1 
ATOM   3777 O O   . SER A 1 1046 ? 209.544 183.022 210.994 1.00 47.77  ? 1057 SER A O   1 
ATOM   3778 C CB  . SER A 1 1046 ? 207.324 184.921 209.581 1.00 47.77  ? 1057 SER A CB  1 
ATOM   3779 O OG  . SER A 1 1046 ? 206.736 184.447 210.780 1.00 47.77  ? 1057 SER A OG  1 
ATOM   3780 N N   . HIS A 1 1047 ? 210.480 184.826 210.007 1.00 45.05  ? 1058 HIS A N   1 
ATOM   3781 C CA  . HIS A 1 1047 ? 211.590 184.946 210.945 1.00 45.05  ? 1058 HIS A CA  1 
ATOM   3782 C C   . HIS A 1 1047 ? 211.738 186.412 211.317 1.00 45.05  ? 1058 HIS A C   1 
ATOM   3783 O O   . HIS A 1 1047 ? 211.848 187.268 210.435 1.00 45.05  ? 1058 HIS A O   1 
ATOM   3784 C CB  . HIS A 1 1047 ? 212.890 184.405 210.339 1.00 45.05  ? 1058 HIS A CB  1 
ATOM   3785 C CG  . HIS A 1 1047 ? 214.130 184.936 210.989 1.00 45.05  ? 1058 HIS A CG  1 
ATOM   3786 N ND1 . HIS A 1 1047 ? 214.742 184.304 212.050 1.00 45.05  ? 1058 HIS A ND1 1 
ATOM   3787 C CD2 . HIS A 1 1047 ? 214.879 186.032 210.722 1.00 45.05  ? 1058 HIS A CD2 1 
ATOM   3788 C CE1 . HIS A 1 1047 ? 215.811 184.992 212.412 1.00 45.05  ? 1058 HIS A CE1 1 
ATOM   3789 N NE2 . HIS A 1 1047 ? 215.916 186.045 211.622 1.00 45.05  ? 1058 HIS A NE2 1 
ATOM   3790 N N   . SER A 1 1048 ? 211.740 186.701 212.615 1.00 48.82  ? 1059 SER A N   1 
ATOM   3791 C CA  . SER A 1 1048 ? 211.826 188.063 213.115 1.00 48.82  ? 1059 SER A CA  1 
ATOM   3792 C C   . SER A 1 1048 ? 213.058 188.224 213.996 1.00 48.82  ? 1059 SER A C   1 
ATOM   3793 O O   . SER A 1 1048 ? 213.557 187.262 214.587 1.00 48.82  ? 1059 SER A O   1 
ATOM   3794 C CB  . SER A 1 1048 ? 210.566 188.446 213.903 1.00 48.82  ? 1059 SER A CB  1 
ATOM   3795 O OG  . SER A 1 1048 ? 210.732 189.694 214.553 1.00 48.82  ? 1059 SER A OG  1 
ATOM   3796 N N   . ARG A 1 1049 ? 213.546 189.463 214.077 1.00 51.95  ? 1060 ARG A N   1 
ATOM   3797 C CA  . ARG A 1 1049 ? 214.735 189.761 214.875 1.00 51.95  ? 1060 ARG A CA  1 
ATOM   3798 C C   . ARG A 1 1049 ? 214.635 191.217 215.328 1.00 51.95  ? 1060 ARG A C   1 
ATOM   3799 O O   . ARG A 1 1049 ? 214.798 192.131 214.515 1.00 51.95  ? 1060 ARG A O   1 
ATOM   3800 C CB  . ARG A 1 1049 ? 216.007 189.508 214.082 1.00 51.95  ? 1060 ARG A CB  1 
ATOM   3801 C CG  . ARG A 1 1049 ? 217.279 189.973 214.773 1.00 51.95  ? 1060 ARG A CG  1 
ATOM   3802 C CD  . ARG A 1 1049 ? 217.510 189.219 216.071 1.00 51.95  ? 1060 ARG A CD  1 
ATOM   3803 N NE  . ARG A 1 1049 ? 218.877 189.367 216.558 1.00 51.95  ? 1060 ARG A NE  1 
ATOM   3804 C CZ  . ARG A 1 1049 ? 219.347 188.793 217.657 1.00 51.95  ? 1060 ARG A CZ  1 
ATOM   3805 N NH1 . ARG A 1 1049 ? 218.584 188.021 218.413 1.00 51.95  ? 1060 ARG A NH1 1 
ATOM   3806 N NH2 . ARG A 1 1049 ? 220.614 188.998 218.005 1.00 51.95  ? 1060 ARG A NH2 1 
ATOM   3807 N N   . THR A 1 1050 ? 214.366 191.416 216.613 1.00 52.44  ? 1061 THR A N   1 
ATOM   3808 C CA  . THR A 1 1050 ? 214.293 192.743 217.204 1.00 52.44  ? 1061 THR A CA  1 
ATOM   3809 C C   . THR A 1 1050 ? 215.574 193.050 217.974 1.00 52.44  ? 1061 THR A C   1 
ATOM   3810 O O   . THR A 1 1050 ? 216.431 192.188 218.180 1.00 52.44  ? 1061 THR A O   1 
ATOM   3811 C CB  . THR A 1 1050 ? 213.076 192.858 218.127 1.00 52.44  ? 1061 THR A CB  1 
ATOM   3812 O OG1 . THR A 1 1050 ? 213.103 191.798 219.091 1.00 52.44  ? 1061 THR A OG1 1 
ATOM   3813 C CG2 . THR A 1 1050 ? 211.789 192.770 217.321 1.00 52.44  ? 1061 THR A CG2 1 
ATOM   3814 N N   . LYS A 1 1051 ? 215.696 194.304 218.401 1.00 55.87  ? 1062 LYS A N   1 
ATOM   3815 C CA  . LYS A 1 1051 ? 216.854 194.764 219.150 1.00 55.87  ? 1062 LYS A CA  1 
ATOM   3816 C C   . LYS A 1 1051 ? 216.409 195.410 220.455 1.00 55.87  ? 1062 LYS A C   1 
ATOM   3817 O O   . LYS A 1 1051 ? 215.279 195.890 220.585 1.00 55.87  ? 1062 LYS A O   1 
ATOM   3818 C CB  . LYS A 1 1051 ? 217.690 195.758 218.333 1.00 55.87  ? 1062 LYS A CB  1 
ATOM   3819 C CG  . LYS A 1 1051 ? 217.038 197.117 218.144 1.00 55.87  ? 1062 LYS A CG  1 
ATOM   3820 C CD  . LYS A 1 1051 ? 217.956 198.068 217.392 1.00 55.87  ? 1062 LYS A CD  1 
ATOM   3821 C CE  . LYS A 1 1051 ? 217.327 199.443 217.241 1.00 55.87  ? 1062 LYS A CE  1 
ATOM   3822 N NZ  . LYS A 1 1051 ? 218.198 200.367 216.464 1.00 55.87  ? 1062 LYS A NZ  1 
ATOM   3823 N N   . THR A 1 1052 ? 217.316 195.412 221.429 1.00 62.07  ? 1063 THR A N   1 
ATOM   3824 C CA  . THR A 1 1052 ? 217.020 196.008 222.724 1.00 62.07  ? 1063 THR A CA  1 
ATOM   3825 C C   . THR A 1 1052 ? 216.941 197.525 222.598 1.00 62.07  ? 1063 THR A C   1 
ATOM   3826 O O   . THR A 1 1052 ? 217.832 198.159 222.025 1.00 62.07  ? 1063 THR A O   1 
ATOM   3827 C CB  . THR A 1 1052 ? 218.086 195.617 223.746 1.00 62.07  ? 1063 THR A CB  1 
ATOM   3828 O OG1 . THR A 1 1052 ? 218.154 194.189 223.847 1.00 62.07  ? 1063 THR A OG1 1 
ATOM   3829 C CG2 . THR A 1 1052 ? 217.757 196.203 225.112 1.00 62.07  ? 1063 THR A CG2 1 
ATOM   3830 N N   . MET A 1 1053 ? 215.872 198.103 223.134 1.00 62.52  ? 1064 MET A N   1 
ATOM   3831 C CA  . MET A 1 1053 ? 215.648 199.539 223.112 1.00 62.52  ? 1064 MET A CA  1 
ATOM   3832 C C   . MET A 1 1053 ? 215.213 199.993 224.495 1.00 62.52  ? 1064 MET A C   1 
ATOM   3833 O O   . MET A 1 1053 ? 214.616 199.213 225.247 1.00 62.52  ? 1064 MET A O   1 
ATOM   3834 C CB  . MET A 1 1053 ? 214.575 199.928 222.082 1.00 62.52  ? 1064 MET A CB  1 
ATOM   3835 C CG  . MET A 1 1053 ? 214.995 199.733 220.638 1.00 62.52  ? 1064 MET A CG  1 
ATOM   3836 S SD  . MET A 1 1053 ? 214.317 201.000 219.551 1.00 62.52  ? 1064 MET A SD  1 
ATOM   3837 C CE  . MET A 1 1053 ? 214.963 202.485 220.316 1.00 62.52  ? 1064 MET A CE  1 
ATOM   3838 N N   . PRO A 1 1054 ? 215.510 201.239 224.864 1.00 67.47  ? 1065 PRO A N   1 
ATOM   3839 C CA  . PRO A 1 1054 ? 215.006 201.762 226.138 1.00 67.47  ? 1065 PRO A CA  1 
ATOM   3840 C C   . PRO A 1 1054 ? 213.488 201.850 226.126 1.00 67.47  ? 1065 PRO A C   1 
ATOM   3841 O O   . PRO A 1 1054 ? 212.867 202.094 225.090 1.00 67.47  ? 1065 PRO A O   1 
ATOM   3842 C CB  . PRO A 1 1054 ? 215.651 203.151 226.234 1.00 67.47  ? 1065 PRO A CB  1 
ATOM   3843 C CG  . PRO A 1 1054 ? 216.004 203.506 224.824 1.00 67.47  ? 1065 PRO A CG  1 
ATOM   3844 C CD  . PRO A 1 1054 ? 216.364 202.212 224.164 1.00 67.47  ? 1065 PRO A CD  1 
ATOM   3845 N N   . ARG A 1 1055 ? 212.891 201.645 227.303 1.00 68.05  ? 1066 ARG A N   1 
ATOM   3846 C CA  . ARG A 1 1055 ? 211.437 201.637 227.409 1.00 68.05  ? 1066 ARG A CA  1 
ATOM   3847 C C   . ARG A 1 1055 ? 210.821 202.990 227.082 1.00 68.05  ? 1066 ARG A C   1 
ATOM   3848 O O   . ARG A 1 1055 ? 209.728 203.036 226.507 1.00 68.05  ? 1066 ARG A O   1 
ATOM   3849 C CB  . ARG A 1 1055 ? 211.008 201.203 228.810 1.00 68.05  ? 1066 ARG A CB  1 
ATOM   3850 C CG  . ARG A 1 1055 ? 209.522 200.917 228.932 1.00 68.05  ? 1066 ARG A CG  1 
ATOM   3851 C CD  . ARG A 1 1055 ? 209.217 200.110 230.176 1.00 68.05  ? 1066 ARG A CD  1 
ATOM   3852 N NE  . ARG A 1 1055 ? 209.759 198.759 230.101 1.00 68.05  ? 1066 ARG A NE  1 
ATOM   3853 C CZ  . ARG A 1 1055 ? 209.897 197.955 231.146 1.00 68.05  ? 1066 ARG A CZ  1 
ATOM   3854 N NH1 . ARG A 1 1055 ? 209.547 198.339 232.363 1.00 68.05  ? 1066 ARG A NH1 1 
ATOM   3855 N NH2 . ARG A 1 1055 ? 210.394 196.735 230.966 1.00 68.05  ? 1066 ARG A NH2 1 
ATOM   3856 N N   . TYR A 1 1056 ? 211.525 204.077 227.417 1.00 67.10  ? 1067 TYR A N   1 
ATOM   3857 C CA  . TYR A 1 1056 ? 210.997 205.447 227.163 1.00 67.10  ? 1067 TYR A CA  1 
ATOM   3858 C C   . TYR A 1 1056 ? 211.986 206.235 226.299 1.00 67.10  ? 1067 TYR A C   1 
ATOM   3859 O O   . TYR A 1 1056 ? 212.693 207.109 226.847 1.00 67.10  ? 1067 TYR A O   1 
ATOM   3860 C CB  . TYR A 1 1056 ? 210.782 206.186 228.487 1.00 67.10  ? 1067 TYR A CB  1 
ATOM   3861 C CG  . TYR A 1 1056 ? 209.733 205.595 229.419 1.00 67.10  ? 1067 TYR A CG  1 
ATOM   3862 C CD1 . TYR A 1 1056 ? 208.520 205.123 228.936 1.00 67.10  ? 1067 TYR A CD1 1 
ATOM   3863 C CD2 . TYR A 1 1056 ? 209.966 205.501 230.786 1.00 67.10  ? 1067 TYR A CD2 1 
ATOM   3864 C CE1 . TYR A 1 1056 ? 207.567 204.585 229.784 1.00 67.10  ? 1067 TYR A CE1 1 
ATOM   3865 C CE2 . TYR A 1 1056 ? 209.022 204.963 231.644 1.00 67.10  ? 1067 TYR A CE2 1 
ATOM   3866 C CZ  . TYR A 1 1056 ? 207.818 204.504 231.141 1.00 67.10  ? 1067 TYR A CZ  1 
ATOM   3867 O OH  . TYR A 1 1056 ? 206.884 203.972 231.981 1.00 67.10  ? 1067 TYR A OH  1 
ATOM   3868 N N   . PRO A 1 1057 ? 212.083 205.982 224.973 1.00 65.44  ? 1068 PRO A N   1 
ATOM   3869 C CA  . PRO A 1 1057 ? 213.084 206.673 224.140 1.00 65.44  ? 1068 PRO A CA  1 
ATOM   3870 C C   . PRO A 1 1057 ? 213.080 208.183 224.316 1.00 65.44  ? 1068 PRO A C   1 
ATOM   3871 O O   . PRO A 1 1057 ? 214.148 208.806 224.292 1.00 65.44  ? 1068 PRO A O   1 
ATOM   3872 C CB  . PRO A 1 1057 ? 212.702 206.275 222.705 1.00 65.44  ? 1068 PRO A CB  1 
ATOM   3873 C CG  . PRO A 1 1057 ? 211.520 205.375 222.800 1.00 65.44  ? 1068 PRO A CG  1 
ATOM   3874 C CD  . PRO A 1 1057 ? 211.280 205.006 224.220 1.00 65.44  ? 1068 PRO A CD  1 
ATOM   3875 N N   . LEU A 1 1058 ? 211.908 208.790 224.501 1.00 67.52  ? 1069 LEU A N   1 
ATOM   3876 C CA  . LEU A 1 1058 ? 211.783 210.241 224.647 1.00 67.52  ? 1069 LEU A CA  1 
ATOM   3877 C C   . LEU A 1 1058 ? 211.637 210.535 226.137 1.00 67.52  ? 1069 LEU A C   1 
ATOM   3878 O O   . LEU A 1 1058 ? 210.604 210.260 226.747 1.00 67.52  ? 1069 LEU A O   1 
ATOM   3879 C CB  . LEU A 1 1058 ? 210.604 210.772 223.839 1.00 67.52  ? 1069 LEU A CB  1 
ATOM   3880 C CG  . LEU A 1 1058 ? 210.772 212.149 223.190 1.00 67.52  ? 1069 LEU A CG  1 
ATOM   3881 C CD1 . LEU A 1 1058 ? 209.701 212.376 222.133 1.00 67.52  ? 1069 LEU A CD1 1 
ATOM   3882 C CD2 . LEU A 1 1058 ? 210.755 213.263 224.222 1.00 67.52  ? 1069 LEU A CD2 1 
ATOM   3883 N N   . MET A 1 1059 ? 212.689 211.104 226.723 1.00 69.50  ? 1070 MET A N   1 
ATOM   3884 C CA  . MET A 1 1059 ? 212.760 211.320 228.163 1.00 69.50  ? 1070 MET A CA  1 
ATOM   3885 C C   . MET A 1 1059 ? 212.305 212.711 228.590 1.00 69.50  ? 1070 MET A C   1 
ATOM   3886 O O   . MET A 1 1059 ? 212.448 213.052 229.769 1.00 69.50  ? 1070 MET A O   1 
ATOM   3887 C CB  . MET A 1 1059 ? 214.188 211.070 228.657 1.00 69.50  ? 1070 MET A CB  1 
ATOM   3888 C CG  . MET A 1 1059 ? 214.513 209.603 228.880 1.00 69.50  ? 1070 MET A CG  1 
ATOM   3889 S SD  . MET A 1 1059 ? 215.303 209.295 230.470 1.00 69.50  ? 1070 MET A SD  1 
ATOM   3890 C CE  . MET A 1 1059 ? 216.607 210.522 230.442 1.00 69.50  ? 1070 MET A CE  1 
ATOM   3891 N N   . ASN A 1 1060 ? 211.773 213.522 227.677 1.00 70.09  ? 1071 ASN A N   1 
ATOM   3892 C CA  . ASN A 1 1060 ? 211.335 214.868 228.020 1.00 70.09  ? 1071 ASN A CA  1 
ATOM   3893 C C   . ASN A 1 1060 ? 209.956 214.909 228.668 1.00 70.09  ? 1071 ASN A C   1 
ATOM   3894 O O   . ASN A 1 1060 ? 209.592 215.942 229.240 1.00 70.09  ? 1071 ASN A O   1 
ATOM   3895 C CB  . ASN A 1 1060 ? 211.336 215.759 226.774 1.00 70.09  ? 1071 ASN A CB  1 
ATOM   3896 C CG  . ASN A 1 1060 ? 212.681 215.782 226.076 1.00 70.09  ? 1071 ASN A CG  1 
ATOM   3897 O OD1 . ASN A 1 1060 ? 213.693 215.366 226.640 1.00 70.09  ? 1071 ASN A OD1 1 
ATOM   3898 N ND2 . ASN A 1 1060 ? 212.699 216.269 224.840 1.00 70.09  ? 1071 ASN A ND2 1 
ATOM   3899 N N   . LEU A 1 1061 ? 209.184 213.825 228.596 1.00 68.11  ? 1072 LEU A N   1 
ATOM   3900 C CA  . LEU A 1 1061 ? 207.848 213.813 229.179 1.00 68.11  ? 1072 LEU A CA  1 
ATOM   3901 C C   . LEU A 1 1061 ? 207.822 213.237 230.586 1.00 68.11  ? 1072 LEU A C   1 
ATOM   3902 O O   . LEU A 1 1061 ? 206.990 213.652 231.401 1.00 68.11  ? 1072 LEU A O   1 
ATOM   3903 C CB  . LEU A 1 1061 ? 206.879 213.015 228.298 1.00 68.11  ? 1072 LEU A CB  1 
ATOM   3904 C CG  . LEU A 1 1061 ? 206.925 213.168 226.776 1.00 68.11  ? 1072 LEU A CG  1 
ATOM   3905 C CD1 . LEU A 1 1061 ? 207.912 212.191 226.155 1.00 68.11  ? 1072 LEU A CD1 1 
ATOM   3906 C CD2 . LEU A 1 1061 ? 205.539 212.985 226.177 1.00 68.11  ? 1072 LEU A CD2 1 
ATOM   3907 N N   . ILE A 1 1062 ? 208.708 212.294 230.889 1.00 71.61  ? 1073 ILE A N   1 
ATOM   3908 C CA  . ILE A 1 1062 ? 208.724 211.621 232.186 1.00 71.61  ? 1073 ILE A CA  1 
ATOM   3909 C C   . ILE A 1 1062 ? 209.124 212.610 233.275 1.00 71.61  ? 1073 ILE A C   1 
ATOM   3910 O O   . ILE A 1 1062 ? 209.919 213.527 233.020 1.00 71.61  ? 1073 ILE A O   1 
ATOM   3911 C CB  . ILE A 1 1062 ? 209.664 210.406 232.166 1.00 71.61  ? 1073 ILE A CB  1 
ATOM   3912 C CG1 . ILE A 1 1062 ? 211.053 210.818 231.678 1.00 71.61  ? 1073 ILE A CG1 1 
ATOM   3913 C CG2 . ILE A 1 1062 ? 209.093 209.309 231.285 1.00 71.61  ? 1073 ILE A CG2 1 
ATOM   3914 C CD1 . ILE A 1 1062 ? 212.174 210.004 232.272 1.00 71.61  ? 1073 ILE A CD1 1 
ATOM   3915 N N   . PRO A 1 1063 ? 208.596 212.472 234.488 1.00 74.12  ? 1074 PRO A N   1 
ATOM   3916 C CA  . PRO A 1 1063 ? 208.975 213.384 235.571 1.00 74.12  ? 1074 PRO A CA  1 
ATOM   3917 C C   . PRO A 1 1063 ? 210.435 213.220 235.962 1.00 74.12  ? 1074 PRO A C   1 
ATOM   3918 O O   . PRO A 1 1063 ? 211.054 212.172 235.763 1.00 74.12  ? 1074 PRO A O   1 
ATOM   3919 C CB  . PRO A 1 1063 ? 208.044 212.971 236.716 1.00 74.12  ? 1074 PRO A CB  1 
ATOM   3920 C CG  . PRO A 1 1063 ? 206.861 212.369 236.016 1.00 74.12  ? 1074 PRO A CG  1 
ATOM   3921 C CD  . PRO A 1 1063 ? 207.484 211.595 234.889 1.00 74.12  ? 1074 PRO A CD  1 
ATOM   3922 N N   . THR A 1 1064 ? 210.986 214.296 236.529 1.00 73.88  ? 1075 THR A N   1 
ATOM   3923 C CA  . THR A 1 1064 ? 212.395 214.299 236.911 1.00 73.88  ? 1075 THR A CA  1 
ATOM   3924 C C   . THR A 1 1064 ? 212.676 213.293 238.021 1.00 73.88  ? 1075 THR A C   1 
ATOM   3925 O O   . THR A 1 1064 ? 213.770 212.720 238.085 1.00 73.88  ? 1075 THR A O   1 
ATOM   3926 C CB  . THR A 1 1064 ? 212.817 215.703 237.346 1.00 73.88  ? 1075 THR A CB  1 
ATOM   3927 O OG1 . THR A 1 1064 ? 212.226 216.009 238.615 1.00 73.88  ? 1075 THR A OG1 1 
ATOM   3928 C CG2 . THR A 1 1064 ? 212.368 216.734 236.322 1.00 73.88  ? 1075 THR A CG2 1 
ATOM   3929 N N   . ASP A 1 1065 ? 211.705 213.072 238.910 1.00 75.91  ? 1076 ASP A N   1 
ATOM   3930 C CA  . ASP A 1 1065 ? 211.914 212.154 240.025 1.00 75.91  ? 1076 ASP A CA  1 
ATOM   3931 C C   . ASP A 1 1065 ? 212.139 210.727 239.540 1.00 75.91  ? 1076 ASP A C   1 
ATOM   3932 O O   . ASP A 1 1065 ? 212.975 210.000 240.090 1.00 75.91  ? 1076 ASP A O   1 
ATOM   3933 C CB  . ASP A 1 1065 ? 210.724 212.211 240.983 1.00 75.91  ? 1076 ASP A CB  1 
ATOM   3934 C CG  . ASP A 1 1065 ? 211.124 211.960 242.423 1.00 75.91  ? 1076 ASP A CG  1 
ATOM   3935 O OD1 . ASP A 1 1065 ? 212.338 211.974 242.715 1.00 75.91  ? 1076 ASP A OD1 1 
ATOM   3936 O OD2 . ASP A 1 1065 ? 210.225 211.746 243.263 1.00 75.91  ? 1076 ASP A OD2 1 
ATOM   3937 N N   . TRP A 1 1066 ? 211.405 210.308 238.513 1.00 76.07  ? 1077 TRP A N   1 
ATOM   3938 C CA  . TRP A 1 1066 ? 211.472 208.945 238.006 1.00 76.07  ? 1077 TRP A CA  1 
ATOM   3939 C C   . TRP A 1 1066 ? 212.486 208.779 236.879 1.00 76.07  ? 1077 TRP A C   1 
ATOM   3940 O O   . TRP A 1 1066 ? 212.522 207.717 236.251 1.00 76.07  ? 1077 TRP A O   1 
ATOM   3941 C CB  . TRP A 1 1066 ? 210.090 208.493 237.521 1.00 76.07  ? 1077 TRP A CB  1 
ATOM   3942 C CG  . TRP A 1 1066 ? 208.965 208.776 238.476 1.00 76.07  ? 1077 TRP A CG  1 
ATOM   3943 C CD1 . TRP A 1 1066 ? 209.057 208.968 239.825 1.00 76.07  ? 1077 TRP A CD1 1 
ATOM   3944 C CD2 . TRP A 1 1066 ? 207.576 208.903 238.148 1.00 76.07  ? 1077 TRP A CD2 1 
ATOM   3945 N NE1 . TRP A 1 1066 ? 207.812 209.204 240.356 1.00 76.07  ? 1077 TRP A NE1 1 
ATOM   3946 C CE2 . TRP A 1 1066 ? 206.886 209.169 239.347 1.00 76.07  ? 1077 TRP A CE2 1 
ATOM   3947 C CE3 . TRP A 1 1066 ? 206.849 208.815 236.957 1.00 76.07  ? 1077 TRP A CE3 1 
ATOM   3948 C CZ2 . TRP A 1 1066 ? 205.505 209.350 239.389 1.00 76.07  ? 1077 TRP A CZ2 1 
ATOM   3949 C CZ3 . TRP A 1 1066 ? 205.479 208.995 237.001 1.00 76.07  ? 1077 TRP A CZ3 1 
ATOM   3950 C CH2 . TRP A 1 1066 ? 204.821 209.259 238.208 1.00 76.07  ? 1077 TRP A CH2 1 
ATOM   3951 N N   . GLN A 1 1067 ? 213.304 209.800 236.612 1.00 77.08  ? 1078 GLN A N   1 
ATOM   3952 C CA  . GLN A 1 1067 ? 214.191 209.764 235.452 1.00 77.08  ? 1078 GLN A CA  1 
ATOM   3953 C C   . GLN A 1 1067 ? 215.208 208.633 235.548 1.00 77.08  ? 1078 GLN A C   1 
ATOM   3954 O O   . GLN A 1 1067 ? 215.462 207.934 234.560 1.00 77.08  ? 1078 GLN A O   1 
ATOM   3955 C CB  . GLN A 1 1067 ? 214.900 211.109 235.296 1.00 77.08  ? 1078 GLN A CB  1 
ATOM   3956 C CG  . GLN A 1 1067 ? 214.111 212.135 234.499 1.00 77.08  ? 1078 GLN A CG  1 
ATOM   3957 C CD  . GLN A 1 1067 ? 214.811 213.476 234.418 1.00 77.08  ? 1078 GLN A CD  1 
ATOM   3958 O OE1 . GLN A 1 1067 ? 215.711 213.768 235.206 1.00 77.08  ? 1078 GLN A OE1 1 
ATOM   3959 N NE2 . GLN A 1 1067 ? 214.400 214.300 233.462 1.00 77.08  ? 1078 GLN A NE2 1 
ATOM   3960 N N   . GLU A 1 1068 ? 215.805 208.438 236.725 1.00 77.83  ? 1079 GLU A N   1 
ATOM   3961 C CA  . GLU A 1 1068 ? 216.832 207.410 236.872 1.00 77.83  ? 1079 GLU A CA  1 
ATOM   3962 C C   . GLU A 1 1068 ? 216.242 206.014 236.700 1.00 77.83  ? 1079 GLU A C   1 
ATOM   3963 O O   . GLU A 1 1068 ? 216.788 205.183 235.961 1.00 77.83  ? 1079 GLU A O   1 
ATOM   3964 C CB  . GLU A 1 1068 ? 217.521 207.542 238.232 1.00 77.83  ? 1079 GLU A CB  1 
ATOM   3965 C CG  . GLU A 1 1068 ? 217.977 208.954 238.587 1.00 77.83  ? 1079 GLU A CG  1 
ATOM   3966 C CD  . GLU A 1 1068 ? 216.870 209.806 239.183 1.00 77.83  ? 1079 GLU A CD  1 
ATOM   3967 O OE1 . GLU A 1 1068 ? 215.703 209.361 239.179 1.00 77.83  ? 1079 GLU A OE1 1 
ATOM   3968 O OE2 . GLU A 1 1068 ? 217.168 210.924 239.653 1.00 77.83  ? 1079 GLU A OE2 1 
ATOM   3969 N N   . GLU A 1 1069 ? 215.122 205.740 237.372 1.00 78.04  ? 1080 GLU A N   1 
ATOM   3970 C CA  . GLU A 1 1069 ? 214.468 204.445 237.220 1.00 78.04  ? 1080 GLU A CA  1 
ATOM   3971 C C   . GLU A 1 1069 ? 213.974 204.243 235.794 1.00 78.04  ? 1080 GLU A C   1 
ATOM   3972 O O   . GLU A 1 1069 ? 214.015 203.125 235.268 1.00 78.04  ? 1080 GLU A O   1 
ATOM   3973 C CB  . GLU A 1 1069 ? 213.315 204.314 238.216 1.00 78.04  ? 1080 GLU A CB  1 
ATOM   3974 C CG  . GLU A 1 1069 ? 213.751 204.007 239.642 1.00 78.04  ? 1080 GLU A CG  1 
ATOM   3975 C CD  . GLU A 1 1069 ? 214.152 202.555 239.840 1.00 78.04  ? 1080 GLU A CD  1 
ATOM   3976 O OE1 . GLU A 1 1069 ? 214.073 201.770 238.871 1.00 78.04  ? 1080 GLU A OE1 1 
ATOM   3977 O OE2 . GLU A 1 1069 ? 214.548 202.197 240.969 1.00 78.04  ? 1080 GLU A OE2 1 
ATOM   3978 N N   . ALA A 1 1070 ? 213.493 205.313 235.156 1.00 76.72  ? 1081 ALA A N   1 
ATOM   3979 C CA  . ALA A 1 1070 ? 213.070 205.212 233.763 1.00 76.72  ? 1081 ALA A CA  1 
ATOM   3980 C C   . ALA A 1 1070 ? 214.236 204.837 232.858 1.00 76.72  ? 1081 ALA A C   1 
ATOM   3981 O O   . ALA A 1 1070 ? 214.088 204.006 231.954 1.00 76.72  ? 1081 ALA A O   1 
ATOM   3982 C CB  . ALA A 1 1070 ? 212.440 206.527 233.309 1.00 76.72  ? 1081 ALA A CB  1 
ATOM   3983 N N   . ALA A 1 1071 ? 215.403 205.444 233.083 1.00 77.71  ? 1082 ALA A N   1 
ATOM   3984 C CA  . ALA A 1 1071 ? 216.584 205.082 232.306 1.00 77.71  ? 1082 ALA A CA  1 
ATOM   3985 C C   . ALA A 1 1071 ? 217.011 203.647 232.578 1.00 77.71  ? 1082 ALA A C   1 
ATOM   3986 O O   . ALA A 1 1071 ? 217.476 202.955 231.665 1.00 77.71  ? 1082 ALA A O   1 
ATOM   3987 C CB  . ALA A 1 1071 ? 217.731 206.046 232.608 1.00 77.71  ? 1082 ALA A CB  1 
ATOM   3988 N N   . ARG A 1 1072 ? 216.861 203.182 233.819 1.00 79.35  ? 1083 ARG A N   1 
ATOM   3989 C CA  . ARG A 1 1072 ? 217.237 201.816 234.160 1.00 79.35  ? 1083 ARG A CA  1 
ATOM   3990 C C   . ARG A 1 1072 ? 216.299 200.769 233.573 1.00 79.35  ? 1083 ARG A C   1 
ATOM   3991 O O   . ARG A 1 1072 ? 216.634 199.580 233.601 1.00 79.35  ? 1083 ARG A O   1 
ATOM   3992 C CB  . ARG A 1 1072 ? 217.300 201.651 235.680 1.00 79.35  ? 1083 ARG A CB  1 
ATOM   3993 C CG  . ARG A 1 1072 ? 218.672 201.923 236.273 1.00 79.35  ? 1083 ARG A CG  1 
ATOM   3994 C CD  . ARG A 1 1072 ? 218.702 201.617 237.764 1.00 79.35  ? 1083 ARG A CD  1 
ATOM   3995 N NE  . ARG A 1 1072 ? 217.805 202.478 238.526 1.00 79.35  ? 1083 ARG A NE  1 
ATOM   3996 C CZ  . ARG A 1 1072 ? 218.003 203.771 238.744 1.00 79.35  ? 1083 ARG A CZ  1 
ATOM   3997 N NH1 . ARG A 1 1072 ? 219.074 204.395 238.281 1.00 79.35  ? 1083 ARG A NH1 1 
ATOM   3998 N NH2 . ARG A 1 1072 ? 217.107 204.454 239.450 1.00 79.35  ? 1083 ARG A NH2 1 
ATOM   3999 N N   . GLN A 1 1073 ? 215.144 201.170 233.047 1.00 76.72  ? 1084 GLN A N   1 
ATOM   4000 C CA  . GLN A 1 1073 ? 214.208 200.236 232.434 1.00 76.72  ? 1084 GLN A CA  1 
ATOM   4001 C C   . GLN A 1 1073 ? 214.417 200.208 230.925 1.00 76.72  ? 1084 GLN A C   1 
ATOM   4002 O O   . GLN A 1 1073 ? 214.504 201.259 230.283 1.00 76.72  ? 1084 GLN A O   1 
ATOM   4003 C CB  . GLN A 1 1073 ? 212.763 200.618 232.758 1.00 76.72  ? 1084 GLN A CB  1 
ATOM   4004 C CG  . GLN A 1 1073 ? 212.432 200.612 234.240 1.00 76.72  ? 1084 GLN A CG  1 
ATOM   4005 C CD  . GLN A 1 1073 ? 211.838 199.296 234.697 1.00 76.72  ? 1084 GLN A CD  1 
ATOM   4006 O OE1 . GLN A 1 1073 ? 211.670 198.369 233.905 1.00 76.72  ? 1084 GLN A OE1 1 
ATOM   4007 N NE2 . GLN A 1 1073 ? 211.517 199.206 235.982 1.00 76.72  ? 1084 GLN A NE2 1 
ATOM   4008 N N   . SER A 1 1074 ? 214.497 199.002 230.366 1.00 72.30  ? 1085 SER A N   1 
ATOM   4009 C CA  . SER A 1 1074 ? 214.682 198.821 228.935 1.00 72.30  ? 1085 SER A CA  1 
ATOM   4010 C C   . SER A 1 1074 ? 213.841 197.647 228.459 1.00 72.30  ? 1085 SER A C   1 
ATOM   4011 O O   . SER A 1 1074 ? 213.565 196.713 229.216 1.00 72.30  ? 1085 SER A O   1 
ATOM   4012 C CB  . SER A 1 1074 ? 216.157 198.585 228.582 1.00 72.30  ? 1085 SER A CB  1 
ATOM   4013 O OG  . SER A 1 1074 ? 216.689 197.501 229.322 1.00 72.30  ? 1085 SER A OG  1 
ATOM   4014 N N   . ASN A 1 1075 ? 213.436 197.704 227.192 1.00 71.27  ? 1086 ASN A N   1 
ATOM   4015 C CA  . ASN A 1 1075 ? 212.663 196.635 226.569 1.00 71.27  ? 1086 ASN A CA  1 
ATOM   4016 C C   . ASN A 1 1075 ? 213.633 195.675 225.889 1.00 71.27  ? 1086 ASN A C   1 
ATOM   4017 O O   . ASN A 1 1075 ? 214.305 196.042 224.921 1.00 71.27  ? 1086 ASN A O   1 
ATOM   4018 C CB  . ASN A 1 1075 ? 211.658 197.206 225.573 1.00 71.27  ? 1086 ASN A CB  1 
ATOM   4019 C CG  . ASN A 1 1075 ? 210.891 196.125 224.835 1.00 71.27  ? 1086 ASN A CG  1 
ATOM   4020 O OD1 . ASN A 1 1075 ? 211.180 195.824 223.677 1.00 71.27  ? 1086 ASN A OD1 1 
ATOM   4021 N ND2 . ASN A 1 1075 ? 209.906 195.537 225.503 1.00 71.27  ? 1086 ASN A ND2 1 
ATOM   4022 N N   . ASP A 1 1076 ? 213.706 194.449 226.399 1.00 69.76  ? 1087 ASP A N   1 
ATOM   4023 C CA  . ASP A 1 1076 ? 214.645 193.471 225.868 1.00 69.76  ? 1087 ASP A CA  1 
ATOM   4024 C C   . ASP A 1 1076 ? 214.242 193.029 224.467 1.00 69.76  ? 1087 ASP A C   1 
ATOM   4025 O O   . ASP A 1 1076 ? 213.057 192.868 224.162 1.00 69.76  ? 1087 ASP A O   1 
ATOM   4026 C CB  . ASP A 1 1076 ? 214.733 192.261 226.800 1.00 69.76  ? 1087 ASP A CB  1 
ATOM   4027 C CG  . ASP A 1 1076 ? 213.387 191.875 227.386 1.00 69.76  ? 1087 ASP A CG  1 
ATOM   4028 O OD1 . ASP A 1 1076 ? 213.310 191.682 228.618 1.00 69.76  ? 1087 ASP A OD1 1 
ATOM   4029 O OD2 . ASP A 1 1076 ? 212.407 191.761 226.621 1.00 69.76  ? 1087 ASP A OD2 1 
ATOM   4030 N N   . GLY A 1 1077 ? 215.243 192.843 223.607 1.00 63.61  ? 1088 GLY A N   1 
ATOM   4031 C CA  . GLY A 1 1077 ? 214.986 192.347 222.271 1.00 63.61  ? 1088 GLY A CA  1 
ATOM   4032 C C   . GLY A 1 1077 ? 215.146 190.840 222.181 1.00 63.61  ? 1088 GLY A C   1 
ATOM   4033 O O   . GLY A 1 1077 ? 215.829 190.211 222.988 1.00 63.61  ? 1088 GLY A O   1 
ATOM   4034 N N   . GLY A 1 1078 ? 214.499 190.256 221.173 1.00 59.92  ? 1089 GLY A N   1 
ATOM   4035 C CA  . GLY A 1 1078 ? 214.553 188.821 220.980 1.00 59.92  ? 1089 GLY A CA  1 
ATOM   4036 C C   . GLY A 1 1078 ? 214.281 188.449 219.539 1.00 59.92  ? 1089 GLY A C   1 
ATOM   4037 O O   . GLY A 1 1078 ? 213.828 189.265 218.734 1.00 59.92  ? 1089 GLY A O   1 
ATOM   4038 N N   . SER A 1 1079 ? 214.567 187.188 219.224 1.00 55.77  ? 1090 SER A N   1 
ATOM   4039 C CA  . SER A 1 1079 ? 214.362 186.639 217.892 1.00 55.77  ? 1090 SER A CA  1 
ATOM   4040 C C   . SER A 1 1079 ? 213.513 185.382 217.989 1.00 55.77  ? 1090 SER A C   1 
ATOM   4041 O O   . SER A 1 1079 ? 213.680 184.580 218.913 1.00 55.77  ? 1090 SER A O   1 
ATOM   4042 C CB  . SER A 1 1079 ? 215.695 186.315 217.209 1.00 55.77  ? 1090 SER A CB  1 
ATOM   4043 O OG  . SER A 1 1079 ? 216.297 185.170 217.786 1.00 55.77  ? 1090 SER A OG  1 
ATOM   4044 N N   . SER A 1 1080 ? 212.603 185.214 217.033 1.00 52.51  ? 1091 SER A N   1 
ATOM   4045 C CA  . SER A 1 1080 ? 211.730 184.052 217.013 1.00 52.51  ? 1091 SER A CA  1 
ATOM   4046 C C   . SER A 1 1080 ? 211.356 183.731 215.574 1.00 52.51  ? 1091 SER A C   1 
ATOM   4047 O O   . SER A 1 1080 ? 211.373 184.598 214.697 1.00 52.51  ? 1091 SER A O   1 
ATOM   4048 C CB  . SER A 1 1080 ? 210.470 184.280 217.856 1.00 52.51  ? 1091 SER A CB  1 
ATOM   4049 O OG  . SER A 1 1080 ? 209.675 185.318 217.312 1.00 52.51  ? 1091 SER A OG  1 
ATOM   4050 N N   . GLN A 1 1081 ? 211.015 182.465 215.344 1.00 52.25  ? 1092 GLN A N   1 
ATOM   4051 C CA  . GLN A 1 1081 ? 210.578 182.010 214.034 1.00 52.25  ? 1092 GLN A CA  1 
ATOM   4052 C C   . GLN A 1 1081 ? 209.524 180.929 214.220 1.00 52.25  ? 1092 GLN A C   1 
ATOM   4053 O O   . GLN A 1 1081 ? 209.497 180.237 215.241 1.00 52.25  ? 1092 GLN A O   1 
ATOM   4054 C CB  . GLN A 1 1081 ? 211.753 181.488 213.196 1.00 52.25  ? 1092 GLN A CB  1 
ATOM   4055 C CG  . GLN A 1 1081 ? 212.354 180.177 213.685 1.00 52.25  ? 1092 GLN A CG  1 
ATOM   4056 C CD  . GLN A 1 1081 ? 211.737 178.963 213.017 1.00 52.25  ? 1092 GLN A CD  1 
ATOM   4057 O OE1 . GLN A 1 1081 ? 211.750 178.841 211.792 1.00 52.25  ? 1092 GLN A OE1 1 
ATOM   4058 N NE2 . GLN A 1 1081 ? 211.195 178.057 213.821 1.00 52.25  ? 1092 GLN A NE2 1 
ATOM   4059 N N   . GLY A 1 1082 ? 208.657 180.793 213.226 1.00 48.75  ? 1093 GLY A N   1 
ATOM   4060 C CA  . GLY A 1 1082 ? 207.601 179.800 213.294 1.00 48.75  ? 1093 GLY A CA  1 
ATOM   4061 C C   . GLY A 1 1082 ? 206.765 179.837 212.034 1.00 48.75  ? 1093 GLY A C   1 
ATOM   4062 O O   . GLY A 1 1082 ? 206.915 180.720 211.183 1.00 48.75  ? 1093 GLY A O   1 
ATOM   4063 N N   . PHE A 1 1083 ? 205.875 178.856 211.931 1.00 47.99  ? 1094 PHE A N   1 
ATOM   4064 C CA  . PHE A 1 1083 ? 204.986 178.736 210.786 1.00 47.99  ? 1094 PHE A CA  1 
ATOM   4065 C C   . PHE A 1 1083 ? 203.677 179.467 211.052 1.00 47.99  ? 1094 PHE A C   1 
ATOM   4066 O O   . PHE A 1 1083 ? 203.162 179.458 212.174 1.00 47.99  ? 1094 PHE A O   1 
ATOM   4067 C CB  . PHE A 1 1083 ? 204.707 177.266 210.470 1.00 47.99  ? 1094 PHE A CB  1 
ATOM   4068 C CG  . PHE A 1 1083 ? 205.881 176.540 209.880 1.00 47.99  ? 1094 PHE A CG  1 
ATOM   4069 C CD1 . PHE A 1 1083 ? 206.137 176.601 208.522 1.00 47.99  ? 1094 PHE A CD1 1 
ATOM   4070 C CD2 . PHE A 1 1083 ? 206.727 175.796 210.685 1.00 47.99  ? 1094 PHE A CD2 1 
ATOM   4071 C CE1 . PHE A 1 1083 ? 207.217 175.934 207.976 1.00 47.99  ? 1094 PHE A CE1 1 
ATOM   4072 C CE2 . PHE A 1 1083 ? 207.807 175.127 210.145 1.00 47.99  ? 1094 PHE A CE2 1 
ATOM   4073 C CZ  . PHE A 1 1083 ? 208.052 175.196 208.789 1.00 47.99  ? 1094 PHE A CZ  1 
ATOM   4074 N N   . GLY A 1 1084 ? 203.143 180.104 210.007 1.00 58.61  ? 1095 GLY A N   1 
ATOM   4075 C CA  . GLY A 1 1084 ? 201.880 180.800 210.111 1.00 58.61  ? 1095 GLY A CA  1 
ATOM   4076 C C   . GLY A 1 1084 ? 200.990 180.479 208.927 1.00 58.61  ? 1095 GLY A C   1 
ATOM   4077 O O   . GLY A 1 1084 ? 201.443 179.959 207.906 1.00 58.61  ? 1095 GLY A O   1 
ATOM   4078 N N   . TYR A 1 1085 ? 199.708 180.799 209.085 1.00 65.84  ? 1096 TYR A N   1 
ATOM   4079 C CA  . TYR A 1 1085 ? 198.727 180.538 208.043 1.00 65.84  ? 1096 TYR A CA  1 
ATOM   4080 C C   . TYR A 1 1085 ? 197.643 181.603 208.096 1.00 65.84  ? 1096 TYR A C   1 
ATOM   4081 O O   . TYR A 1 1085 ? 197.405 182.217 209.139 1.00 65.84  ? 1096 TYR A O   1 
ATOM   4082 C CB  . TYR A 1 1085 ? 198.111 179.142 208.189 1.00 65.84  ? 1096 TYR A CB  1 
ATOM   4083 C CG  . TYR A 1 1085 ? 197.083 179.038 209.292 1.00 65.84  ? 1096 TYR A CG  1 
ATOM   4084 C CD1 . TYR A 1 1085 ? 197.471 178.927 210.620 1.00 65.84  ? 1096 TYR A CD1 1 
ATOM   4085 C CD2 . TYR A 1 1085 ? 195.724 179.044 209.005 1.00 65.84  ? 1096 TYR A CD2 1 
ATOM   4086 C CE1 . TYR A 1 1085 ? 196.537 178.831 211.633 1.00 65.84  ? 1096 TYR A CE1 1 
ATOM   4087 C CE2 . TYR A 1 1085 ? 194.782 178.948 210.011 1.00 65.84  ? 1096 TYR A CE2 1 
ATOM   4088 C CZ  . TYR A 1 1085 ? 195.194 178.842 211.322 1.00 65.84  ? 1096 TYR A CZ  1 
ATOM   4089 O OH  . TYR A 1 1085 ? 194.259 178.746 212.328 1.00 65.84  ? 1096 TYR A OH  1 
ATOM   4090 N N   . THR A 1 1086 ? 196.988 181.815 206.957 1.00 66.00  ? 1097 THR A N   1 
ATOM   4091 C CA  . THR A 1 1086 ? 195.886 182.760 206.859 1.00 66.00  ? 1097 THR A CA  1 
ATOM   4092 C C   . THR A 1 1086 ? 194.832 182.205 205.912 1.00 66.00  ? 1097 THR A C   1 
ATOM   4093 O O   . THR A 1 1086 ? 195.161 181.589 204.895 1.00 66.00  ? 1097 THR A O   1 
ATOM   4094 C CB  . THR A 1 1086 ? 196.361 184.140 206.377 1.00 66.00  ? 1097 THR A CB  1 
ATOM   4095 O OG1 . THR A 1 1086 ? 195.228 184.987 206.149 1.00 66.00  ? 1097 THR A OG1 1 
ATOM   4096 C CG2 . THR A 1 1086 ? 197.173 184.020 205.096 1.00 66.00  ? 1097 THR A CG2 1 
ATOM   4097 N N   . ALA A 1 1087 ? 193.565 182.417 206.261 1.00 69.60  ? 1098 ALA A N   1 
ATOM   4098 C CA  . ALA A 1 1087 ? 192.440 181.946 205.465 1.00 69.60  ? 1098 ALA A CA  1 
ATOM   4099 C C   . ALA A 1 1087 ? 191.510 183.113 205.178 1.00 69.60  ? 1098 ALA A C   1 
ATOM   4100 O O   . ALA A 1 1087 ? 191.152 183.864 206.091 1.00 69.60  ? 1098 ALA A O   1 
ATOM   4101 C CB  . ALA A 1 1087 ? 191.681 180.825 206.182 1.00 69.60  ? 1098 ALA A CB  1 
ATOM   4102 N N   . ARG A 1 1088 ? 191.160 183.260 203.898 1.00 73.39  ? 1099 ARG A N   1 
ATOM   4103 C CA  . ARG A 1 1088 ? 190.258 184.361 203.482 1.00 73.39  ? 1099 ARG A CA  1 
ATOM   4104 C C   . ARG A 1 1088 ? 189.166 183.789 202.574 1.00 73.39  ? 1099 ARG A C   1 
ATOM   4105 O O   . ARG A 1 1088 ? 189.504 183.010 201.659 1.00 73.39  ? 1099 ARG A O   1 
ATOM   4106 C CB  . ARG A 1 1088 ? 191.021 185.468 202.751 1.00 73.39  ? 1099 ARG A CB  1 
ATOM   4107 C CG  . ARG A 1 1088 ? 190.150 186.678 202.445 1.00 73.39  ? 1099 ARG A CG  1 
ATOM   4108 C CD  . ARG A 1 1088 ? 190.894 187.689 201.595 1.00 73.39  ? 1099 ARG A CD  1 
ATOM   4109 N NE  . ARG A 1 1088 ? 191.342 187.092 200.333 1.00 73.39  ? 1099 ARG A NE  1 
ATOM   4110 C CZ  . ARG A 1 1088 ? 192.026 187.739 199.400 1.00 73.39  ? 1099 ARG A CZ  1 
ATOM   4111 N NH1 . ARG A 1 1088 ? 192.362 189.003 199.585 1.00 73.39  ? 1099 ARG A NH1 1 
ATOM   4112 N NH2 . ARG A 1 1088 ? 192.372 187.121 198.285 1.00 73.39  ? 1099 ARG A NH2 1 
ATOM   4113 N N   . ALA A 1 1089 ? 187.915 184.158 202.826 1.00 72.11  ? 1100 ALA A N   1 
ATOM   4114 C CA  . ALA A 1 1089 ? 186.782 183.699 202.038 1.00 72.11  ? 1100 ALA A CA  1 
ATOM   4115 C C   . ALA A 1 1089 ? 185.892 184.882 201.693 1.00 72.11  ? 1100 ALA A C   1 
ATOM   4116 O O   . ALA A 1 1089 ? 185.738 185.807 202.495 1.00 72.11  ? 1100 ALA A O   1 
ATOM   4117 C CB  . ALA A 1 1089 ? 185.973 182.633 202.785 1.00 72.11  ? 1100 ALA A CB  1 
ATOM   4118 N N   . LEU A 1 1090 ? 185.310 184.849 200.495 1.00 72.41  ? 1101 LEU A N   1 
ATOM   4119 C CA  . LEU A 1 1090 ? 184.416 185.897 200.025 1.00 72.41  ? 1101 LEU A CA  1 
ATOM   4120 C C   . LEU A 1 1090 ? 183.166 185.273 199.422 1.00 72.41  ? 1101 LEU A C   1 
ATOM   4121 O O   . LEU A 1 1090 ? 183.189 184.138 198.938 1.00 72.41  ? 1101 LEU A O   1 
ATOM   4122 C CB  . LEU A 1 1090 ? 185.091 186.803 198.984 1.00 72.41  ? 1101 LEU A CB  1 
ATOM   4123 C CG  . LEU A 1 1090 ? 186.021 187.905 199.494 1.00 72.41  ? 1101 LEU A CG  1 
ATOM   4124 C CD1 . LEU A 1 1090 ? 187.402 187.355 199.804 1.00 72.41  ? 1101 LEU A CD1 1 
ATOM   4125 C CD2 . LEU A 1 1090 ? 186.109 189.040 198.487 1.00 72.41  ? 1101 LEU A CD2 1 
ATOM   4126 N N   . LEU A 1 1091 ? 182.071 186.029 199.457 1.00 71.41  ? 1102 LEU A N   1 
ATOM   4127 C CA  . LEU A 1 1091 ? 180.806 185.581 198.895 1.00 71.41  ? 1102 LEU A CA  1 
ATOM   4128 C C   . LEU A 1 1091 ? 179.990 186.797 198.480 1.00 71.41  ? 1102 LEU A C   1 
ATOM   4129 O O   . LEU A 1 1091 ? 180.000 187.821 199.167 1.00 71.41  ? 1102 LEU A O   1 
ATOM   4130 C CB  . LEU A 1 1091 ? 180.018 184.729 199.896 1.00 71.41  ? 1102 LEU A CB  1 
ATOM   4131 C CG  . LEU A 1 1091 ? 178.677 184.170 199.416 1.00 71.41  ? 1102 LEU A CG  1 
ATOM   4132 C CD1 . LEU A 1 1091 ? 178.887 183.137 198.321 1.00 71.41  ? 1102 LEU A CD1 1 
ATOM   4133 C CD2 . LEU A 1 1091 ? 177.895 183.577 200.577 1.00 71.41  ? 1102 LEU A CD2 1 
ATOM   4134 N N   . GLU A 1 1092 ? 179.293 186.677 197.351 1.00 76.37  ? 1103 GLU A N   1 
ATOM   4135 C CA  . GLU A 1 1092 ? 178.441 187.742 196.841 1.00 76.37  ? 1103 GLU A CA  1 
ATOM   4136 C C   . GLU A 1 1092 ? 177.279 187.129 196.075 1.00 76.37  ? 1103 GLU A C   1 
ATOM   4137 O O   . GLU A 1 1092 ? 177.470 186.201 195.284 1.00 76.37  ? 1103 GLU A O   1 
ATOM   4138 C CB  . GLU A 1 1092 ? 179.225 188.699 195.933 1.00 76.37  ? 1103 GLU A CB  1 
ATOM   4139 C CG  . GLU A 1 1092 ? 178.372 189.767 195.268 1.00 76.37  ? 1103 GLU A CG  1 
ATOM   4140 C CD  . GLU A 1 1092 ? 179.162 191.017 194.931 1.00 76.37  ? 1103 GLU A CD  1 
ATOM   4141 O OE1 . GLU A 1 1092 ? 180.395 191.014 195.126 1.00 76.37  ? 1103 GLU A OE1 1 
ATOM   4142 O OE2 . GLU A 1 1092 ? 178.549 192.003 194.470 1.00 76.37  ? 1103 GLU A OE2 1 
ATOM   4143 N N   . ARG A 1 1093 ? 176.072 187.639 196.341 1.00 75.42  ? 1104 ARG A N   1 
ATOM   4144 C CA  . ARG A 1 1093 ? 174.861 187.114 195.658 1.00 75.42  ? 1104 ARG A CA  1 
ATOM   4145 C C   . ARG A 1 1093 ? 174.002 188.279 195.144 1.00 75.42  ? 1104 ARG A C   1 
ATOM   4146 O O   . ARG A 1 1093 ? 173.734 189.213 195.931 1.00 75.42  ? 1104 ARG A O   1 
ATOM   4147 C CB  . ARG A 1 1093 ? 174.014 186.232 196.582 1.00 75.42  ? 1104 ARG A CB  1 
ATOM   4148 C CG  . ARG A 1 1093 ? 172.901 185.553 195.798 1.00 75.42  ? 1104 ARG A CG  1 
ATOM   4149 C CD  . ARG A 1 1093 ? 171.720 185.135 196.655 1.00 75.42  ? 1104 ARG A CD  1 
ATOM   4150 N NE  . ARG A 1 1093 ? 170.673 184.526 195.828 1.00 75.42  ? 1104 ARG A NE  1 
ATOM   4151 C CZ  . ARG A 1 1093 ? 169.441 185.000 195.703 1.00 75.42  ? 1104 ARG A CZ  1 
ATOM   4152 N NH1 . ARG A 1 1093 ? 168.998 185.921 196.539 1.00 75.42  ? 1104 ARG A NH1 1 
ATOM   4153 N NH2 . ARG A 1 1093 ? 168.654 184.549 194.742 1.00 75.42  ? 1104 ARG A NH2 1 
ATOM   4154 N N   . ARG A 1 1094 ? 173.588 188.217 193.878 1.00 78.78  ? 1105 ARG A N   1 
ATOM   4155 C CA  . ARG A 1 1094 ? 172.716 189.257 193.272 1.00 78.78  ? 1105 ARG A CA  1 
ATOM   4156 C C   . ARG A 1 1094 ? 171.264 188.829 193.496 1.00 78.78  ? 1105 ARG A C   1 
ATOM   4157 O O   . ARG A 1 1094 ? 170.805 187.899 192.797 1.00 78.78  ? 1105 ARG A O   1 
ATOM   4158 C CB  . ARG A 1 1094 ? 172.971 189.435 191.771 1.00 78.78  ? 1105 ARG A CB  1 
ATOM   4159 C CG  . ARG A 1 1094 ? 171.926 190.290 191.069 1.00 78.78  ? 1105 ARG A CG  1 
ATOM   4160 C CD  . ARG A 1 1094 ? 172.210 190.527 189.594 1.00 78.78  ? 1105 ARG A CD  1 
ATOM   4161 N NE  . ARG A 1 1094 ? 172.172 189.301 188.790 1.00 78.78  ? 1105 ARG A NE  1 
ATOM   4162 C CZ  . ARG A 1 1094 ? 173.176 188.858 188.046 1.00 78.78  ? 1105 ARG A CZ  1 
ATOM   4163 N NH1 . ARG A 1 1094 ? 174.320 189.518 188.020 1.00 78.78  ? 1105 ARG A NH1 1 
ATOM   4164 N NH2 . ARG A 1 1094 ? 173.033 187.758 187.330 1.00 78.78  ? 1105 ARG A NH2 1 
ATOM   4165 N N   . VAL A 1 1095 ? 170.581 189.463 194.442 1.00 76.84  ? 1106 VAL A N   1 
ATOM   4166 C CA  . VAL A 1 1095 ? 169.206 189.120 194.791 1.00 76.84  ? 1106 VAL A CA  1 
ATOM   4167 C C   . VAL A 1 1095 ? 168.270 189.634 193.707 1.00 76.84  ? 1106 VAL A C   1 
ATOM   4168 O O   . VAL A 1 1095 ? 167.596 188.852 193.028 1.00 76.84  ? 1106 VAL A O   1 
ATOM   4169 C CB  . VAL A 1 1095 ? 168.818 189.692 196.167 1.00 76.84  ? 1106 VAL A CB  1 
ATOM   4170 C CG1 . VAL A 1 1095 ? 167.396 189.290 196.525 1.00 76.84  ? 1106 VAL A CG1 1 
ATOM   4171 C CG2 . VAL A 1 1095 ? 169.794 189.220 197.230 1.00 76.84  ? 1106 VAL A CG2 1 
ATOM   4172 N N   . THR A 1 1096 ? 168.224 190.948 193.539 1.00 77.53  ? 1107 THR A N   1 
ATOM   4173 C CA  . THR A 1 1096 ? 167.418 191.589 192.510 1.00 77.53  ? 1107 THR A CA  1 
ATOM   4174 C C   . THR A 1 1096 ? 168.359 192.312 191.539 1.00 77.53  ? 1107 THR A C   1 
ATOM   4175 O O   . THR A 1 1096 ? 169.575 192.227 191.741 1.00 77.53  ? 1107 THR A O   1 
ATOM   4176 C CB  . THR A 1 1096 ? 166.360 192.472 193.173 1.00 77.53  ? 1107 THR A CB  1 
ATOM   4177 O OG1 . THR A 1 1096 ? 165.771 193.336 192.193 1.00 77.53  ? 1107 THR A OG1 1 
ATOM   4178 C CG2 . THR A 1 1096 ? 166.984 193.315 194.273 1.00 77.53  ? 1107 THR A CG2 1 
ATOM   4179 N N   . SER A 1 1097 ? 167.871 193.013 190.516 1.00 73.95  ? 1108 SER A N   1 
ATOM   4180 C CA  . SER A 1 1097 ? 168.738 193.721 189.588 1.00 73.95  ? 1108 SER A CA  1 
ATOM   4181 C C   . SER A 1 1097 ? 169.378 194.968 190.175 1.00 73.95  ? 1108 SER A C   1 
ATOM   4182 O O   . SER A 1 1097 ? 170.323 195.491 189.575 1.00 73.95  ? 1108 SER A O   1 
ATOM   4183 C CB  . SER A 1 1097 ? 167.962 194.119 188.323 1.00 73.95  ? 1108 SER A CB  1 
ATOM   4184 O OG  . SER A 1 1097 ? 166.971 195.087 188.618 1.00 73.95  ? 1108 SER A OG  1 
ATOM   4185 N N   . ASN A 1 1098 ? 168.907 195.451 191.324 1.00 73.15  ? 1109 ASN A N   1 
ATOM   4186 C CA  . ASN A 1 1098 ? 169.409 196.684 191.913 1.00 73.15  ? 1109 ASN A CA  1 
ATOM   4187 C C   . ASN A 1 1098 ? 170.170 196.482 193.213 1.00 73.15  ? 1109 ASN A C   1 
ATOM   4188 O O   . ASN A 1 1098 ? 171.092 197.250 193.494 1.00 73.15  ? 1109 ASN A O   1 
ATOM   4189 C CB  . ASN A 1 1098 ? 168.252 197.660 192.169 1.00 73.15  ? 1109 ASN A CB  1 
ATOM   4190 C CG  . ASN A 1 1098 ? 167.712 198.278 190.893 1.00 73.15  ? 1109 ASN A CG  1 
ATOM   4191 O OD1 . ASN A 1 1098 ? 167.285 197.570 189.981 1.00 73.15  ? 1109 ASN A OD1 1 
ATOM   4192 N ND2 . ASN A 1 1098 ? 167.733 199.604 190.818 1.00 73.15  ? 1109 ASN A ND2 1 
ATOM   4193 N N   . TRP A 1 1099 ? 169.815 195.476 194.007 1.00 72.63  ? 1110 TRP A N   1 
ATOM   4194 C CA  . TRP A 1 1099 ? 170.414 195.256 195.316 1.00 72.63  ? 1110 TRP A CA  1 
ATOM   4195 C C   . TRP A 1 1099 ? 171.271 193.998 195.294 1.00 72.63  ? 1110 TRP A C   1 
ATOM   4196 O O   . TRP A 1 1099 ? 170.813 192.936 194.860 1.00 72.63  ? 1110 TRP A O   1 
ATOM   4197 C CB  . TRP A 1 1099 ? 169.337 195.138 196.398 1.00 72.63  ? 1110 TRP A CB  1 
ATOM   4198 C CG  . TRP A 1 1099 ? 168.502 196.369 196.550 1.00 72.63  ? 1110 TRP A CG  1 
ATOM   4199 C CD1 . TRP A 1 1099 ? 167.344 196.660 195.893 1.00 72.63  ? 1110 TRP A CD1 1 
ATOM   4200 C CD2 . TRP A 1 1099 ? 168.760 197.479 197.419 1.00 72.63  ? 1110 TRP A CD2 1 
ATOM   4201 N NE1 . TRP A 1 1099 ? 166.864 197.883 196.297 1.00 72.63  ? 1110 TRP A NE1 1 
ATOM   4202 C CE2 . TRP A 1 1099 ? 167.716 198.406 197.233 1.00 72.63  ? 1110 TRP A CE2 1 
ATOM   4203 C CE3 . TRP A 1 1099 ? 169.773 197.778 198.335 1.00 72.63  ? 1110 TRP A CE3 1 
ATOM   4204 C CZ2 . TRP A 1 1099 ? 167.655 199.611 197.929 1.00 72.63  ? 1110 TRP A CZ2 1 
ATOM   4205 C CZ3 . TRP A 1 1099 ? 169.711 198.975 199.025 1.00 72.63  ? 1110 TRP A CZ3 1 
ATOM   4206 C CH2 . TRP A 1 1099 ? 168.660 199.876 198.818 1.00 72.63  ? 1110 TRP A CH2 1 
ATOM   4207 N N   . PHE A 1 1100 ? 172.509 194.124 195.764 1.00 74.10  ? 1111 PHE A N   1 
ATOM   4208 C CA  . PHE A 1 1100 ? 173.418 193.000 195.920 1.00 74.10  ? 1111 PHE A CA  1 
ATOM   4209 C C   . PHE A 1 1100 ? 173.838 192.890 197.379 1.00 74.10  ? 1111 PHE A C   1 
ATOM   4210 O O   . PHE A 1 1100 ? 174.010 193.898 198.069 1.00 74.10  ? 1111 PHE A O   1 
ATOM   4211 C CB  . PHE A 1 1100 ? 174.667 193.146 195.038 1.00 74.10  ? 1111 PHE A CB  1 
ATOM   4212 C CG  . PHE A 1 1100 ? 174.380 193.629 193.645 1.00 74.10  ? 1111 PHE A CG  1 
ATOM   4213 C CD1 . PHE A 1 1100 ? 174.350 194.984 193.359 1.00 74.10  ? 1111 PHE A CD1 1 
ATOM   4214 C CD2 . PHE A 1 1100 ? 174.151 192.729 192.619 1.00 74.10  ? 1111 PHE A CD2 1 
ATOM   4215 C CE1 . PHE A 1 1100 ? 174.091 195.431 192.078 1.00 74.10  ? 1111 PHE A CE1 1 
ATOM   4216 C CE2 . PHE A 1 1100 ? 173.892 193.170 191.335 1.00 74.10  ? 1111 PHE A CE2 1 
ATOM   4217 C CZ  . PHE A 1 1100 ? 173.861 194.523 191.065 1.00 74.10  ? 1111 PHE A CZ  1 
ATOM   4218 N N   . VAL A 1 1101 ? 174.002 191.654 197.844 1.00 72.77  ? 1112 VAL A N   1 
ATOM   4219 C CA  . VAL A 1 1101 ? 174.417 191.382 199.215 1.00 72.77  ? 1112 VAL A CA  1 
ATOM   4220 C C   . VAL A 1 1101 ? 175.609 190.438 199.182 1.00 72.77  ? 1112 VAL A C   1 
ATOM   4221 O O   . VAL A 1 1101 ? 175.736 189.611 198.273 1.00 72.77  ? 1112 VAL A O   1 
ATOM   4222 C CB  . VAL A 1 1101 ? 173.270 190.787 200.057 1.00 72.77  ? 1112 VAL A CB  1 
ATOM   4223 C CG1 . VAL A 1 1101 ? 172.166 191.814 200.254 1.00 72.77  ? 1112 VAL A CG1 1 
ATOM   4224 C CG2 . VAL A 1 1101 ? 172.726 189.528 199.403 1.00 72.77  ? 1112 VAL A CG2 1 
ATOM   4225 N N   . GLY A 1 1102 ? 176.488 190.568 200.172 1.00 74.01  ? 1113 GLY A N   1 
ATOM   4226 C CA  . GLY A 1 1102 ? 177.660 189.716 200.246 1.00 74.01  ? 1113 GLY A CA  1 
ATOM   4227 C C   . GLY A 1 1102 ? 178.324 189.821 201.600 1.00 74.01  ? 1113 GLY A C   1 
ATOM   4228 O O   . GLY A 1 1102 ? 178.004 190.691 202.413 1.00 74.01  ? 1113 GLY A O   1 
ATOM   4229 N N   . THR A 1 1103 ? 179.265 188.909 201.830 1.00 72.12  ? 1114 THR A N   1 
ATOM   4230 C CA  . THR A 1 1103 ? 180.011 188.873 203.079 1.00 72.12  ? 1114 THR A CA  1 
ATOM   4231 C C   . THR A 1 1103 ? 181.386 188.279 202.816 1.00 72.12  ? 1114 THR A C   1 
ATOM   4232 O O   . THR A 1 1103 ? 181.614 187.609 201.806 1.00 72.12  ? 1114 THR A O   1 
ATOM   4233 C CB  . THR A 1 1103 ? 179.279 188.062 204.155 1.00 72.12  ? 1114 THR A CB  1 
ATOM   4234 O OG1 . THR A 1 1103 ? 180.022 188.113 205.380 1.00 72.12  ? 1114 THR A OG1 1 
ATOM   4235 C CG2 . THR A 1 1103 ? 179.130 186.611 203.720 1.00 72.12  ? 1114 THR A CG2 1 
ATOM   4236 N N   . ALA A 1 1104 ? 182.306 188.538 203.743 1.00 70.75  ? 1115 ALA A N   1 
ATOM   4237 C CA  . ALA A 1 1104 ? 183.660 188.019 203.636 1.00 70.75  ? 1115 ALA A CA  1 
ATOM   4238 C C   . ALA A 1 1104 ? 184.247 187.859 205.030 1.00 70.75  ? 1115 ALA A C   1 
ATOM   4239 O O   . ALA A 1 1104 ? 183.957 188.646 205.935 1.00 70.75  ? 1115 ALA A O   1 
ATOM   4240 C CB  . ALA A 1 1104 ? 184.551 188.934 202.787 1.00 70.75  ? 1115 ALA A CB  1 
ATOM   4241 N N   . ILE A 1 1105 ? 185.076 186.831 205.190 1.00 66.32  ? 1116 ILE A N   1 
ATOM   4242 C CA  . ILE A 1 1105 ? 185.743 186.538 206.452 1.00 66.32  ? 1116 ILE A CA  1 
ATOM   4243 C C   . ILE A 1 1105 ? 187.239 186.430 206.189 1.00 66.32  ? 1116 ILE A C   1 
ATOM   4244 O O   . ILE A 1 1105 ? 187.663 185.734 205.260 1.00 66.32  ? 1116 ILE A O   1 
ATOM   4245 C CB  . ILE A 1 1105 ? 185.205 185.246 207.099 1.00 66.32  ? 1116 ILE A CB  1 
ATOM   4246 C CG1 . ILE A 1 1105 ? 186.096 184.816 208.267 1.00 66.32  ? 1116 ILE A CG1 1 
ATOM   4247 C CG2 . ILE A 1 1105 ? 185.073 184.135 206.068 1.00 66.32  ? 1116 ILE A CG2 1 
ATOM   4248 C CD1 . ILE A 1 1105 ? 185.590 183.596 209.004 1.00 66.32  ? 1116 ILE A CD1 1 
ATOM   4249 N N   . ASP A 1 1106 ? 188.033 187.130 206.997 1.00 70.55  ? 1117 ASP A N   1 
ATOM   4250 C CA  . ASP A 1 1106 ? 189.486 187.115 206.879 1.00 70.55  ? 1117 ASP A CA  1 
ATOM   4251 C C   . ASP A 1 1106 ? 190.074 186.656 208.203 1.00 70.55  ? 1117 ASP A C   1 
ATOM   4252 O O   . ASP A 1 1106 ? 189.767 187.230 209.253 1.00 70.55  ? 1117 ASP A O   1 
ATOM   4253 C CB  . ASP A 1 1106 ? 190.024 188.498 206.498 1.00 70.55  ? 1117 ASP A CB  1 
ATOM   4254 C CG  . ASP A 1 1106 ? 191.524 188.498 206.266 1.00 70.55  ? 1117 ASP A CG  1 
ATOM   4255 O OD1 . ASP A 1 1106 ? 192.121 189.594 206.239 1.00 70.55  ? 1117 ASP A OD1 1 
ATOM   4256 O OD2 . ASP A 1 1106 ? 192.105 187.404 206.103 1.00 70.55  ? 1117 ASP A OD2 1 
ATOM   4257 N N   . ILE A 1 1107 ? 190.915 185.626 208.153 1.00 66.88  ? 1118 ILE A N   1 
ATOM   4258 C CA  . ILE A 1 1107 ? 191.581 185.083 209.331 1.00 66.88  ? 1118 ILE A CA  1 
ATOM   4259 C C   . ILE A 1 1107 ? 193.078 185.288 209.155 1.00 66.88  ? 1118 ILE A C   1 
ATOM   4260 O O   . ILE A 1 1107 ? 193.661 184.838 208.161 1.00 66.88  ? 1118 ILE A O   1 
ATOM   4261 C CB  . ILE A 1 1107 ? 191.246 183.598 209.537 1.00 66.88  ? 1118 ILE A CB  1 
ATOM   4262 C CG1 . ILE A 1 1107 ? 189.733 183.405 209.646 1.00 66.88  ? 1118 ILE A CG1 1 
ATOM   4263 C CG2 . ILE A 1 1107 ? 191.944 183.063 210.776 1.00 66.88  ? 1118 ILE A CG2 1 
ATOM   4264 C CD1 . ILE A 1 1107 ? 189.306 181.955 209.711 1.00 66.88  ? 1118 ILE A CD1 1 
ATOM   4265 N N   . GLN A 1 1108 ? 193.699 185.967 210.116 1.00 66.81  ? 1119 GLN A N   1 
ATOM   4266 C CA  . GLN A 1 1108 ? 195.123 186.284 210.069 1.00 66.81  ? 1119 GLN A CA  1 
ATOM   4267 C C   . GLN A 1 1108 ? 195.813 185.612 211.250 1.00 66.81  ? 1119 GLN A C   1 
ATOM   4268 O O   . GLN A 1 1108 ? 195.590 185.991 212.405 1.00 66.81  ? 1119 GLN A O   1 
ATOM   4269 C CB  . GLN A 1 1108 ? 195.344 187.795 210.090 1.00 66.81  ? 1119 GLN A CB  1 
ATOM   4270 C CG  . GLN A 1 1108 ? 194.818 188.521 208.863 1.00 66.81  ? 1119 GLN A CG  1 
ATOM   4271 C CD  . GLN A 1 1108 ? 195.661 188.270 207.628 1.00 66.81  ? 1119 GLN A CD  1 
ATOM   4272 O OE1 . GLN A 1 1108 ? 196.819 187.864 207.725 1.00 66.81  ? 1119 GLN A OE1 1 
ATOM   4273 N NE2 . GLN A 1 1108 ? 195.083 188.513 206.458 1.00 66.81  ? 1119 GLN A NE2 1 
ATOM   4274 N N   . GLN A 1 1109 ? 196.648 184.619 210.958 1.00 66.45  ? 1120 GLN A N   1 
ATOM   4275 C CA  . GLN A 1 1109 ? 197.437 183.910 211.959 1.00 66.45  ? 1120 GLN A CA  1 
ATOM   4276 C C   . GLN A 1 1109 ? 198.869 183.735 211.474 1.00 66.45  ? 1120 GLN A C   1 
ATOM   4277 O O   . GLN A 1 1109 ? 199.469 182.666 211.616 1.00 66.45  ? 1120 GLN A O   1 
ATOM   4278 C CB  . GLN A 1 1109 ? 196.812 182.558 212.297 1.00 66.45  ? 1120 GLN A CB  1 
ATOM   4279 C CG  . GLN A 1 1109 ? 195.454 182.643 212.979 1.00 66.45  ? 1120 GLN A CG  1 
ATOM   4280 C CD  . GLN A 1 1109 ? 195.558 182.831 214.481 1.00 66.45  ? 1120 GLN A CD  1 
ATOM   4281 O OE1 . GLN A 1 1109 ? 196.384 183.603 214.969 1.00 66.45  ? 1120 GLN A OE1 1 
ATOM   4282 N NE2 . GLN A 1 1109 ? 194.716 182.123 215.224 1.00 66.45  ? 1120 GLN A NE2 1 
ATOM   4283 N N   . ALA A 1 1110 ? 199.438 184.791 210.893 1.00 65.03  ? 1121 ALA A N   1 
ATOM   4284 C CA  . ALA A 1 1110 ? 200.773 184.749 210.314 1.00 65.03  ? 1121 ALA A CA  1 
ATOM   4285 C C   . ALA A 1 1110 ? 201.837 185.328 211.240 1.00 65.03  ? 1121 ALA A C   1 
ATOM   4286 O O   . ALA A 1 1110 ? 202.922 185.687 210.765 1.00 65.03  ? 1121 ALA A O   1 
ATOM   4287 C CB  . ALA A 1 1110 ? 200.788 185.485 208.972 1.00 65.03  ? 1121 ALA A CB  1 
ATOM   4288 N N   . LYS A 1 1111 ? 201.530 185.468 212.534 1.00 64.90  ? 1122 LYS A N   1 
ATOM   4289 C CA  . LYS A 1 1111 ? 202.479 185.889 213.563 1.00 64.90  ? 1122 LYS A CA  1 
ATOM   4290 C C   . LYS A 1 1111 ? 202.810 187.375 213.425 1.00 64.90  ? 1122 LYS A C   1 
ATOM   4291 O O   . LYS A 1 1111 ? 203.469 187.959 214.292 1.00 64.90  ? 1122 LYS A O   1 
ATOM   4292 C CB  . LYS A 1 1111 ? 203.742 185.012 213.508 1.00 64.90  ? 1122 LYS A CB  1 
ATOM   4293 C CG  . LYS A 1 1111 ? 204.847 185.356 214.497 1.00 64.90  ? 1122 LYS A CG  1 
ATOM   4294 C CD  . LYS A 1 1111 ? 205.960 184.322 214.460 1.00 64.90  ? 1122 LYS A CD  1 
ATOM   4295 C CE  . LYS A 1 1111 ? 207.079 184.681 215.422 1.00 64.90  ? 1122 LYS A CE  1 
ATOM   4296 N NZ  . LYS A 1 1111 ? 206.607 184.732 216.832 1.00 64.90  ? 1122 LYS A NZ  1 
ATOM   4297 N N   . ASP A 1 1112 ? 202.314 188.011 212.366 1.00 67.18  ? 1123 ASP A N   1 
ATOM   4298 C CA  . ASP A 1 1112 ? 202.565 189.426 212.125 1.00 67.18  ? 1123 ASP A CA  1 
ATOM   4299 C C   . ASP A 1 1112 ? 201.597 190.338 212.870 1.00 67.18  ? 1123 ASP A C   1 
ATOM   4300 O O   . ASP A 1 1112 ? 201.519 191.528 212.543 1.00 67.18  ? 1123 ASP A O   1 
ATOM   4301 C CB  . ASP A 1 1112 ? 202.503 189.723 210.623 1.00 67.18  ? 1123 ASP A CB  1 
ATOM   4302 C CG  . ASP A 1 1112 ? 201.230 189.210 209.979 1.00 67.18  ? 1123 ASP A CG  1 
ATOM   4303 O OD1 . ASP A 1 1112 ? 200.441 188.534 210.671 1.00 67.18  ? 1123 ASP A OD1 1 
ATOM   4304 O OD2 . ASP A 1 1112 ? 201.018 189.484 208.779 1.00 67.18  ? 1123 ASP A OD2 1 
ATOM   4305 N N   . TYR A 1 1113 ? 200.860 189.807 213.847 1.00 67.34  ? 1124 TYR A N   1 
ATOM   4306 C CA  . TYR A 1 1113 ? 199.920 190.569 214.669 1.00 67.34  ? 1124 TYR A CA  1 
ATOM   4307 C C   . TYR A 1 1113 ? 198.818 191.223 213.841 1.00 67.34  ? 1124 TYR A C   1 
ATOM   4308 O O   . TYR A 1 1113 ? 198.266 192.253 214.240 1.00 67.34  ? 1124 TYR A O   1 
ATOM   4309 C CB  . TYR A 1 1113 ? 200.647 191.627 215.509 1.00 67.34  ? 1124 TYR A CB  1 
ATOM   4310 C CG  . TYR A 1 1113 ? 201.674 191.057 216.461 1.00 67.34  ? 1124 TYR A CG  1 
ATOM   4311 C CD1 . TYR A 1 1113 ? 202.977 190.814 216.044 1.00 67.34  ? 1124 TYR A CD1 1 
ATOM   4312 C CD2 . TYR A 1 1113 ? 201.343 190.763 217.777 1.00 67.34  ? 1124 TYR A CD2 1 
ATOM   4313 C CE1 . TYR A 1 1113 ? 203.920 190.293 216.910 1.00 67.34  ? 1124 TYR A CE1 1 
ATOM   4314 C CE2 . TYR A 1 1113 ? 202.279 190.242 218.651 1.00 67.34  ? 1124 TYR A CE2 1 
ATOM   4315 C CZ  . TYR A 1 1113 ? 203.565 190.009 218.212 1.00 67.34  ? 1124 TYR A CZ  1 
ATOM   4316 O OH  . TYR A 1 1113 ? 204.501 189.491 219.078 1.00 67.34  ? 1124 TYR A OH  1 
ATOM   4317 N N   . ALA A 1 1114 ? 198.488 190.646 212.693 1.00 68.92  ? 1125 ALA A N   1 
ATOM   4318 C CA  . ALA A 1 1114 ? 197.429 191.199 211.859 1.00 68.92  ? 1125 ALA A CA  1 
ATOM   4319 C C   . ALA A 1 1114 ? 196.066 190.811 212.424 1.00 68.92  ? 1125 ALA A C   1 
ATOM   4320 O O   . ALA A 1 1114 ? 195.815 189.624 212.662 1.00 68.92  ? 1125 ALA A O   1 
ATOM   4321 C CB  . ALA A 1 1114 ? 197.568 190.706 210.421 1.00 68.92  ? 1125 ALA A CB  1 
ATOM   4322 N N   . PRO A 1 1115 ? 195.173 191.769 212.664 1.00 71.86  ? 1126 PRO A N   1 
ATOM   4323 C CA  . PRO A 1 1115 ? 193.843 191.421 213.171 1.00 71.86  ? 1126 PRO A CA  1 
ATOM   4324 C C   . PRO A 1 1115 ? 192.999 190.724 212.115 1.00 71.86  ? 1126 PRO A C   1 
ATOM   4325 O O   . PRO A 1 1115 ? 193.170 190.930 210.911 1.00 71.86  ? 1126 PRO A O   1 
ATOM   4326 C CB  . PRO A 1 1115 ? 193.244 192.779 213.554 1.00 71.86  ? 1126 PRO A CB  1 
ATOM   4327 C CG  . PRO A 1 1115 ? 193.942 193.754 212.668 1.00 71.86  ? 1126 PRO A CG  1 
ATOM   4328 C CD  . PRO A 1 1115 ? 195.333 193.219 212.462 1.00 71.86  ? 1126 PRO A CD  1 
ATOM   4329 N N   . SER A 1 1116 ? 192.076 189.891 212.585 1.00 72.97  ? 1127 SER A N   1 
ATOM   4330 C CA  . SER A 1 1116 ? 191.141 189.197 211.713 1.00 72.97  ? 1127 SER A CA  1 
ATOM   4331 C C   . SER A 1 1116 ? 189.973 190.110 211.362 1.00 72.97  ? 1127 SER A C   1 
ATOM   4332 O O   . SER A 1 1116 ? 189.630 191.027 212.113 1.00 72.97  ? 1127 SER A O   1 
ATOM   4333 C CB  . SER A 1 1116 ? 190.624 187.920 212.378 1.00 72.97  ? 1127 SER A CB  1 
ATOM   4334 O OG  . SER A 1 1116 ? 189.929 188.216 213.576 1.00 72.97  ? 1127 SER A OG  1 
ATOM   4335 N N   . HIS A 1 1117 ? 189.362 189.852 210.207 1.00 71.93  ? 1128 HIS A N   1 
ATOM   4336 C CA  . HIS A 1 1117 ? 188.288 190.691 209.692 1.00 71.93  ? 1128 HIS A CA  1 
ATOM   4337 C C   . HIS A 1 1117 ? 187.101 189.832 209.283 1.00 71.93  ? 1128 HIS A C   1 
ATOM   4338 O O   . HIS A 1 1117 ? 187.266 188.835 208.573 1.00 71.93  ? 1128 HIS A O   1 
ATOM   4339 C CB  . HIS A 1 1117 ? 188.767 191.526 208.500 1.00 71.93  ? 1128 HIS A CB  1 
ATOM   4340 C CG  . HIS A 1 1117 ? 189.167 192.923 208.862 1.00 71.93  ? 1128 HIS A CG  1 
ATOM   4341 N ND1 . HIS A 1 1117 ? 188.259 193.954 208.962 1.00 71.93  ? 1128 HIS A ND1 1 
ATOM   4342 C CD2 . HIS A 1 1117 ? 190.378 193.458 209.146 1.00 71.93  ? 1128 HIS A CD2 1 
ATOM   4343 C CE1 . HIS A 1 1117 ? 188.893 195.065 209.293 1.00 71.93  ? 1128 HIS A CE1 1 
ATOM   4344 N NE2 . HIS A 1 1117 ? 190.179 194.791 209.411 1.00 71.93  ? 1128 HIS A NE2 1 
ATOM   4345 N N   . PHE A 1 1118 ? 185.912 190.247 209.741 1.00 70.78  ? 1129 PHE A N   1 
ATOM   4346 C CA  . PHE A 1 1118 ? 184.637 189.599 209.332 1.00 70.78  ? 1129 PHE A CA  1 
ATOM   4347 C C   . PHE A 1 1118 ? 183.729 190.748 208.908 1.00 70.78  ? 1129 PHE A C   1 
ATOM   4348 O O   . PHE A 1 1118 ? 183.444 191.601 209.770 1.00 70.78  ? 1129 PHE A O   1 
ATOM   4349 C CB  . PHE A 1 1118 ? 183.993 188.765 210.440 1.00 70.78  ? 1129 PHE A CB  1 
ATOM   4350 C CG  . PHE A 1 1118 ? 182.699 188.097 209.994 1.00 70.78  ? 1129 PHE A CG  1 
ATOM   4351 C CD1 . PHE A 1 1118 ? 182.717 186.849 209.384 1.00 70.78  ? 1129 PHE A CD1 1 
ATOM   4352 C CD2 . PHE A 1 1118 ? 181.471 188.723 210.177 1.00 70.78  ? 1129 PHE A CD2 1 
ATOM   4353 C CE1 . PHE A 1 1118 ? 181.540 186.244 208.973 1.00 70.78  ? 1129 PHE A CE1 1 
ATOM   4354 C CE2 . PHE A 1 1118 ? 180.298 188.113 209.764 1.00 70.78  ? 1129 PHE A CE2 1 
ATOM   4355 C CZ  . PHE A 1 1118 ? 180.334 186.876 209.164 1.00 70.78  ? 1129 PHE A CZ  1 
ATOM   4356 N N   . LEU A 1 1119 ? 183.279 190.782 207.653 1.00 71.23  ? 1130 LEU A N   1 
ATOM   4357 C CA  . LEU A 1 1119 ? 182.533 191.911 207.117 1.00 71.23  ? 1130 LEU A CA  1 
ATOM   4358 C C   . LEU A 1 1119 ? 181.281 191.430 206.400 1.00 71.23  ? 1130 LEU A C   1 
ATOM   4359 O O   . LEU A 1 1119 ? 181.251 190.340 205.823 1.00 71.23  ? 1130 LEU A O   1 
ATOM   4360 C CB  . LEU A 1 1119 ? 183.410 192.751 206.169 1.00 71.23  ? 1130 LEU A CB  1 
ATOM   4361 C CG  . LEU A 1 1119 ? 183.999 192.137 204.892 1.00 71.23  ? 1130 LEU A CG  1 
ATOM   4362 C CD1 . LEU A 1 1119 ? 183.015 192.144 203.725 1.00 71.23  ? 1130 LEU A CD1 1 
ATOM   4363 C CD2 . LEU A 1 1119 ? 185.290 192.846 204.508 1.00 71.23  ? 1130 LEU A CD2 1 
ATOM   4364 N N   . LEU A 1 1120 ? 180.244 192.264 206.449 1.00 72.78  ? 1131 LEU A N   1 
ATOM   4365 C CA  . LEU A 1 1120 ? 179.012 192.062 205.699 1.00 72.78  ? 1131 LEU A CA  1 
ATOM   4366 C C   . LEU A 1 1120 ? 178.609 193.391 205.080 1.00 72.78  ? 1131 LEU A C   1 
ATOM   4367 O O   . LEU A 1 1120 ? 178.744 194.439 205.719 1.00 72.78  ? 1131 LEU A O   1 
ATOM   4368 C CB  . LEU A 1 1120 ? 177.895 191.512 206.598 1.00 72.78  ? 1131 LEU A CB  1 
ATOM   4369 C CG  . LEU A 1 1120 ? 177.663 192.169 207.962 1.00 72.78  ? 1131 LEU A CG  1 
ATOM   4370 C CD1 . LEU A 1 1120 ? 176.673 193.324 207.874 1.00 72.78  ? 1131 LEU A CD1 1 
ATOM   4371 C CD2 . LEU A 1 1120 ? 177.197 191.140 208.981 1.00 72.78  ? 1131 LEU A CD2 1 
ATOM   4372 N N   . TYR A 1 1121 ? 178.129 193.354 203.838 1.00 73.36  ? 1132 TYR A N   1 
ATOM   4373 C CA  . TYR A 1 1121 ? 177.806 194.577 203.119 1.00 73.36  ? 1132 TYR A CA  1 
ATOM   4374 C C   . TYR A 1 1121 ? 176.669 194.327 202.139 1.00 73.36  ? 1132 TYR A C   1 
ATOM   4375 O O   . TYR A 1 1121 ? 176.418 193.197 201.714 1.00 73.36  ? 1132 TYR A O   1 
ATOM   4376 C CB  . TYR A 1 1121 ? 179.030 195.131 202.377 1.00 73.36  ? 1132 TYR A CB  1 
ATOM   4377 C CG  . TYR A 1 1121 ? 179.283 194.495 201.028 1.00 73.36  ? 1132 TYR A CG  1 
ATOM   4378 C CD1 . TYR A 1 1121 ? 179.543 193.136 200.915 1.00 73.36  ? 1132 TYR A CD1 1 
ATOM   4379 C CD2 . TYR A 1 1121 ? 179.264 195.257 199.868 1.00 73.36  ? 1132 TYR A CD2 1 
ATOM   4380 C CE1 . TYR A 1 1121 ? 179.776 192.553 199.685 1.00 73.36  ? 1132 TYR A CE1 1 
ATOM   4381 C CE2 . TYR A 1 1121 ? 179.495 194.683 198.633 1.00 73.36  ? 1132 TYR A CE2 1 
ATOM   4382 C CZ  . TYR A 1 1121 ? 179.751 193.331 198.548 1.00 73.36  ? 1132 TYR A CZ  1 
ATOM   4383 O OH  . TYR A 1 1121 ? 179.982 192.757 197.320 1.00 73.36  ? 1132 TYR A OH  1 
ATOM   4384 N N   . VAL A 1 1122 ? 175.982 195.412 201.785 1.00 71.09  ? 1133 VAL A N   1 
ATOM   4385 C CA  . VAL A 1 1122 ? 174.905 195.397 200.804 1.00 71.09  ? 1133 VAL A CA  1 
ATOM   4386 C C   . VAL A 1 1122 ? 175.147 196.524 199.808 1.00 71.09  ? 1133 VAL A C   1 
ATOM   4387 O O   . VAL A 1 1122 ? 175.440 197.659 200.200 1.00 71.09  ? 1133 VAL A O   1 
ATOM   4388 C CB  . VAL A 1 1122 ? 173.520 195.534 201.474 1.00 71.09  ? 1133 VAL A CB  1 
ATOM   4389 C CG1 . VAL A 1 1122 ? 173.513 196.685 202.470 1.00 71.09  ? 1133 VAL A CG1 1 
ATOM   4390 C CG2 . VAL A 1 1122 ? 172.432 195.717 200.427 1.00 71.09  ? 1133 VAL A CG2 1 
ATOM   4391 N N   . ARG A 1 1123 ? 175.038 196.207 198.520 1.00 72.00  ? 1134 ARG A N   1 
ATOM   4392 C CA  . ARG A 1 1123 ? 175.304 197.158 197.450 1.00 72.00  ? 1134 ARG A CA  1 
ATOM   4393 C C   . ARG A 1 1123 ? 174.026 197.448 196.678 1.00 72.00  ? 1134 ARG A C   1 
ATOM   4394 O O   . ARG A 1 1123 ? 173.276 196.531 196.331 1.00 72.00  ? 1134 ARG A O   1 
ATOM   4395 C CB  . ARG A 1 1123 ? 176.382 196.630 196.496 1.00 72.00  ? 1134 ARG A CB  1 
ATOM   4396 C CG  . ARG A 1 1123 ? 176.774 197.610 195.402 1.00 72.00  ? 1134 ARG A CG  1 
ATOM   4397 C CD  . ARG A 1 1123 ? 178.067 197.192 194.722 1.00 72.00  ? 1134 ARG A CD  1 
ATOM   4398 N NE  . ARG A 1 1123 ? 179.136 196.957 195.684 1.00 72.00  ? 1134 ARG A NE  1 
ATOM   4399 C CZ  . ARG A 1 1123 ? 180.248 197.676 195.760 1.00 72.00  ? 1134 ARG A CZ  1 
ATOM   4400 N NH1 . ARG A 1 1123 ? 180.471 198.692 194.943 1.00 72.00  ? 1134 ARG A NH1 1 
ATOM   4401 N NH2 . ARG A 1 1123 ? 181.157 197.368 196.680 1.00 72.00  ? 1134 ARG A NH2 1 
ATOM   4402 N N   . TYR A 1 1124 ? 173.786 198.729 196.411 1.00 73.31  ? 1135 TYR A N   1 
ATOM   4403 C CA  . TYR A 1 1124 ? 172.621 199.187 195.665 1.00 73.31  ? 1135 TYR A CA  1 
ATOM   4404 C C   . TYR A 1 1124 ? 173.086 199.781 194.342 1.00 73.31  ? 1135 TYR A C   1 
ATOM   4405 O O   . TYR A 1 1124 ? 173.959 200.654 194.325 1.00 73.31  ? 1135 TYR A O   1 
ATOM   4406 C CB  . TYR A 1 1124 ? 171.830 200.220 196.467 1.00 73.31  ? 1135 TYR A CB  1 
ATOM   4407 C CG  . TYR A 1 1124 ? 170.643 200.801 195.729 1.00 73.31  ? 1135 TYR A CG  1 
ATOM   4408 C CD1 . TYR A 1 1124 ? 169.830 199.999 194.938 1.00 73.31  ? 1135 TYR A CD1 1 
ATOM   4409 C CD2 . TYR A 1 1124 ? 170.341 202.153 195.818 1.00 73.31  ? 1135 TYR A CD2 1 
ATOM   4410 C CE1 . TYR A 1 1124 ? 168.747 200.528 194.261 1.00 73.31  ? 1135 TYR A CE1 1 
ATOM   4411 C CE2 . TYR A 1 1124 ? 169.261 202.691 195.145 1.00 73.31  ? 1135 TYR A CE2 1 
ATOM   4412 C CZ  . TYR A 1 1124 ? 168.467 201.874 194.368 1.00 73.31  ? 1135 TYR A CZ  1 
ATOM   4413 O OH  . TYR A 1 1124 ? 167.390 202.404 193.696 1.00 73.31  ? 1135 TYR A OH  1 
ATOM   4414 N N   . SER A 1 1125 ? 172.504 199.310 193.242 1.00 72.83  ? 1136 SER A N   1 
ATOM   4415 C CA  . SER A 1 1125 ? 172.800 199.821 191.909 1.00 72.83  ? 1136 SER A CA  1 
ATOM   4416 C C   . SER A 1 1125 ? 171.563 200.527 191.371 1.00 72.83  ? 1136 SER A C   1 
ATOM   4417 O O   . SER A 1 1125 ? 170.487 199.924 191.288 1.00 72.83  ? 1136 SER A O   1 
ATOM   4418 C CB  . SER A 1 1125 ? 173.229 198.693 190.971 1.00 72.83  ? 1136 SER A CB  1 
ATOM   4419 O OG  . SER A 1 1125 ? 173.424 199.173 189.653 1.00 72.83  ? 1136 SER A OG  1 
ATOM   4420 N N   . ALA A 1 1126 ? 171.718 201.801 191.008 1.00 70.68  ? 1137 ALA A N   1 
ATOM   4421 C CA  . ALA A 1 1126 ? 170.580 202.577 190.524 1.00 70.68  ? 1137 ALA A CA  1 
ATOM   4422 C C   . ALA A 1 1126 ? 170.144 202.115 189.139 1.00 70.68  ? 1137 ALA A C   1 
ATOM   4423 O O   . ALA A 1 1126 ? 168.950 201.919 188.883 1.00 70.68  ? 1137 ALA A O   1 
ATOM   4424 C CB  . ALA A 1 1126 ? 170.928 204.065 190.514 1.00 70.68  ? 1137 ALA A CB  1 
ATOM   4425 N N   . ALA A 1 1127 ? 171.102 201.940 188.227 1.00 74.13  ? 1138 ALA A N   1 
ATOM   4426 C CA  . ALA A 1 1127 ? 170.769 201.560 186.858 1.00 74.13  ? 1138 ALA A CA  1 
ATOM   4427 C C   . ALA A 1 1127 ? 170.226 200.138 186.796 1.00 74.13  ? 1138 ALA A C   1 
ATOM   4428 O O   . ALA A 1 1127 ? 169.191 199.879 186.170 1.00 74.13  ? 1138 ALA A O   1 
ATOM   4429 C CB  . ALA A 1 1127 ? 171.997 201.711 185.959 1.00 74.13  ? 1138 ALA A CB  1 
ATOM   4430 N N   . GLY A 1 1128 ? 170.912 199.200 187.442 1.00 76.81  ? 1139 GLY A N   1 
ATOM   4431 C CA  . GLY A 1 1128 ? 170.511 197.808 187.400 1.00 76.81  ? 1139 GLY A CA  1 
ATOM   4432 C C   . GLY A 1 1128 ? 171.472 196.953 186.602 1.00 76.81  ? 1139 GLY A C   1 
ATOM   4433 O O   . GLY A 1 1128 ? 171.519 197.046 185.372 1.00 76.81  ? 1139 GLY A O   1 
ATOM   4434 N N   . TRP A 1 1129 ? 172.243 196.114 187.288 1.00 76.51  ? 1140 TRP A N   1 
ATOM   4435 C CA  . TRP A 1 1129 ? 173.267 195.286 186.660 1.00 76.51  ? 1140 TRP A CA  1 
ATOM   4436 C C   . TRP A 1 1129 ? 172.818 193.830 186.692 1.00 76.51  ? 1140 TRP A C   1 
ATOM   4437 O O   . TRP A 1 1129 ? 172.690 193.237 187.768 1.00 76.51  ? 1140 TRP A O   1 
ATOM   4438 C CB  . TRP A 1 1129 ? 174.611 195.458 187.363 1.00 76.51  ? 1140 TRP A CB  1 
ATOM   4439 C CG  . TRP A 1 1129 ? 175.751 194.812 186.639 1.00 76.51  ? 1140 TRP A CG  1 
ATOM   4440 C CD1 . TRP A 1 1129 ? 176.438 193.697 187.021 1.00 76.51  ? 1140 TRP A CD1 1 
ATOM   4441 C CD2 . TRP A 1 1129 ? 176.342 195.245 185.408 1.00 76.51  ? 1140 TRP A CD2 1 
ATOM   4442 N NE1 . TRP A 1 1129 ? 177.417 193.406 186.104 1.00 76.51  ? 1140 TRP A NE1 1 
ATOM   4443 C CE2 . TRP A 1 1129 ? 177.380 194.342 185.104 1.00 76.51  ? 1140 TRP A CE2 1 
ATOM   4444 C CE3 . TRP A 1 1129 ? 176.095 196.307 184.534 1.00 76.51  ? 1140 TRP A CE3 1 
ATOM   4445 C CZ2 . TRP A 1 1129 ? 178.169 194.469 183.963 1.00 76.51  ? 1140 TRP A CZ2 1 
ATOM   4446 C CZ3 . TRP A 1 1129 ? 176.879 196.431 183.402 1.00 76.51  ? 1140 TRP A CZ3 1 
ATOM   4447 C CH2 . TRP A 1 1129 ? 177.903 195.518 183.127 1.00 76.51  ? 1140 TRP A CH2 1 
ATOM   4448 N N   . GLN A 1 1130 ? 172.582 193.259 185.510 1.00 80.93  ? 1141 GLN A N   1 
ATOM   4449 C CA  . GLN A 1 1130 ? 172.288 191.840 185.359 1.00 80.93  ? 1141 GLN A CA  1 
ATOM   4450 C C   . GLN A 1 1130 ? 173.396 191.107 184.610 1.00 80.93  ? 1141 GLN A C   1 
ATOM   4451 O O   . GLN A 1 1130 ? 173.179 189.993 184.121 1.00 80.93  ? 1141 GLN A O   1 
ATOM   4452 C CB  . GLN A 1 1130 ? 170.948 191.645 184.648 1.00 80.93  ? 1141 GLN A CB  1 
ATOM   4453 C CG  . GLN A 1 1130 ? 169.735 191.731 185.557 1.00 80.93  ? 1141 GLN A CG  1 
ATOM   4454 C CD  . GLN A 1 1130 ? 169.555 190.489 186.405 1.00 80.93  ? 1141 GLN A CD  1 
ATOM   4455 O OE1 . GLN A 1 1130 ? 170.019 189.406 186.047 1.00 80.93  ? 1141 GLN A OE1 1 
ATOM   4456 N NE2 . GLN A 1 1130 ? 168.876 190.637 187.536 1.00 80.93  ? 1141 GLN A NE2 1 
ATOM   4457 N N   . GLY A 1 1131 ? 174.576 191.713 184.506 1.00 81.02  ? 1142 GLY A N   1 
ATOM   4458 C CA  . GLY A 1 1131 ? 175.679 191.134 183.769 1.00 81.02  ? 1142 GLY A CA  1 
ATOM   4459 C C   . GLY A 1 1131 ? 176.522 190.201 184.613 1.00 81.02  ? 1142 GLY A C   1 
ATOM   4460 O O   . GLY A 1 1131 ? 176.093 189.687 185.649 1.00 81.02  ? 1142 GLY A O   1 
ATOM   4461 N N   . ASP A 1 1132 ? 177.751 189.982 184.149 1.00 83.69  ? 1143 ASP A N   1 
ATOM   4462 C CA  . ASP A 1 1132 ? 178.660 189.067 184.825 1.00 83.69  ? 1143 ASP A CA  1 
ATOM   4463 C C   . ASP A 1 1132 ? 179.065 189.611 186.190 1.00 83.69  ? 1143 ASP A C   1 
ATOM   4464 O O   . ASP A 1 1132 ? 179.277 190.814 186.362 1.00 83.69  ? 1143 ASP A O   1 
ATOM   4465 C CB  . ASP A 1 1132 ? 179.903 188.826 183.968 1.00 83.69  ? 1143 ASP A CB  1 
ATOM   4466 C CG  . ASP A 1 1132 ? 179.873 187.483 183.265 1.00 83.69  ? 1143 ASP A CG  1 
ATOM   4467 O OD1 . ASP A 1 1132 ? 179.065 186.618 183.664 1.00 83.69  ? 1143 ASP A OD1 1 
ATOM   4468 O OD2 . ASP A 1 1132 ? 180.661 187.291 182.315 1.00 83.69  ? 1143 ASP A OD2 1 
ATOM   4469 N N   . MET A 1 1133 ? 179.168 188.712 187.165 1.00 79.14  ? 1144 MET A N   1 
ATOM   4470 C CA  . MET A 1 1133 ? 179.545 189.104 188.513 1.00 79.14  ? 1144 MET A CA  1 
ATOM   4471 C C   . MET A 1 1133 ? 181.032 189.444 188.584 1.00 79.14  ? 1144 MET A C   1 
ATOM   4472 O O   . MET A 1 1133 ? 181.829 189.074 187.717 1.00 79.14  ? 1144 MET A O   1 
ATOM   4473 C CB  . MET A 1 1133 ? 179.206 187.993 189.510 1.00 79.14  ? 1144 MET A CB  1 
ATOM   4474 C CG  . MET A 1 1133 ? 177.711 187.767 189.727 1.00 79.14  ? 1144 MET A CG  1 
ATOM   4475 S SD  . MET A 1 1133 ? 176.775 189.098 190.524 1.00 79.14  ? 1144 MET A SD  1 
ATOM   4476 C CE  . MET A 1 1133 ? 178.031 189.989 191.445 1.00 79.14  ? 1144 MET A CE  1 
ATOM   4477 N N   . ASP A 1 1134 ? 181.376 190.141 189.671 1.00 80.43  ? 1145 ASP A N   1 
ATOM   4478 C CA  . ASP A 1 1134 ? 182.771 190.614 189.853 1.00 80.43  ? 1145 ASP A CA  1 
ATOM   4479 C C   . ASP A 1 1134 ? 183.702 189.458 190.206 1.00 80.43  ? 1145 ASP A C   1 
ATOM   4480 O O   . ASP A 1 1134 ? 183.354 188.661 191.103 1.00 80.43  ? 1145 ASP A O   1 
ATOM   4481 C CB  . ASP A 1 1134 ? 182.833 191.697 190.916 1.00 80.43  ? 1145 ASP A CB  1 
ATOM   4482 C CG  . ASP A 1 1134 ? 181.794 192.801 190.783 1.00 80.43  ? 1145 ASP A CG  1 
ATOM   4483 O OD1 . ASP A 1 1134 ? 180.989 192.737 189.831 1.00 80.43  ? 1145 ASP A OD1 1 
ATOM   4484 O OD2 . ASP A 1 1134 ? 181.796 193.712 191.636 1.00 80.43  ? 1145 ASP A OD2 1 
ATOM   4485 N N   . LEU A 1 1135 ? 184.841 189.384 189.527 1.00 78.84  ? 1146 LEU A N   1 
ATOM   4486 C CA  . LEU A 1 1135 ? 185.857 188.372 189.809 1.00 78.84  ? 1146 LEU A CA  1 
ATOM   4487 C C   . LEU A 1 1135 ? 187.162 189.066 190.175 1.00 78.84  ? 1146 LEU A C   1 
ATOM   4488 O O   . LEU A 1 1135 ? 187.869 189.570 189.285 1.00 78.84  ? 1146 LEU A O   1 
ATOM   4489 C CB  . LEU A 1 1135 ? 186.057 187.445 188.617 1.00 78.84  ? 1146 LEU A CB  1 
ATOM   4490 C CG  . LEU A 1 1135 ? 185.161 186.209 188.546 1.00 78.84  ? 1146 LEU A CG  1 
ATOM   4491 C CD1 . LEU A 1 1135 ? 185.681 185.232 187.504 1.00 78.84  ? 1146 LEU A CD1 1 
ATOM   4492 C CD2 . LEU A 1 1135 ? 185.057 185.536 189.907 1.00 78.84  ? 1146 LEU A CD2 1 
ATOM   4493 N N   . PRO A 1 1136 ? 187.521 189.116 191.463 1.00 78.90  ? 1147 PRO A N   1 
ATOM   4494 C CA  . PRO A 1 1136 ? 186.789 188.613 192.633 1.00 78.90  ? 1147 PRO A CA  1 
ATOM   4495 C C   . PRO A 1 1136 ? 185.724 189.594 193.108 1.00 78.90  ? 1147 PRO A C   1 
ATOM   4496 O O   . PRO A 1 1136 ? 185.667 190.720 192.621 1.00 78.90  ? 1147 PRO A O   1 
ATOM   4497 C CB  . PRO A 1 1136 ? 187.904 188.435 193.668 1.00 78.90  ? 1147 PRO A CB  1 
ATOM   4498 C CG  . PRO A 1 1136 ? 188.851 189.556 193.357 1.00 78.90  ? 1147 PRO A CG  1 
ATOM   4499 C CD  . PRO A 1 1136 ? 188.815 189.709 191.851 1.00 78.90  ? 1147 PRO A CD  1 
ATOM   4500 N N   . PRO A 1 1137 ? 184.858 189.194 194.040 1.00 78.05  ? 1148 PRO A N   1 
ATOM   4501 C CA  . PRO A 1 1137 ? 183.954 190.167 194.663 1.00 78.05  ? 1148 PRO A CA  1 
ATOM   4502 C C   . PRO A 1 1137 ? 184.746 191.271 195.348 1.00 78.05  ? 1148 PRO A C   1 
ATOM   4503 O O   . PRO A 1 1137 ? 185.829 191.040 195.889 1.00 78.05  ? 1148 PRO A O   1 
ATOM   4504 C CB  . PRO A 1 1137 ? 183.168 189.325 195.673 1.00 78.05  ? 1148 PRO A CB  1 
ATOM   4505 C CG  . PRO A 1 1137 ? 183.212 187.944 195.118 1.00 78.05  ? 1148 PRO A CG  1 
ATOM   4506 C CD  . PRO A 1 1137 ? 184.558 187.814 194.462 1.00 78.05  ? 1148 PRO A CD  1 
ATOM   4507 N N   . GLN A 1 1138 ? 184.198 192.483 195.314 1.00 79.06  ? 1149 GLN A N   1 
ATOM   4508 C CA  . GLN A 1 1138 ? 184.939 193.639 195.800 1.00 79.06  ? 1149 GLN A CA  1 
ATOM   4509 C C   . GLN A 1 1138 ? 184.269 194.251 197.024 1.00 79.06  ? 1149 GLN A C   1 
ATOM   4510 O O   . GLN A 1 1138 ? 183.358 195.077 196.887 1.00 79.06  ? 1149 GLN A O   1 
ATOM   4511 C CB  . GLN A 1 1138 ? 185.073 194.688 194.694 1.00 79.06  ? 1149 GLN A CB  1 
ATOM   4512 C CG  . GLN A 1 1138 ? 185.397 194.113 193.324 1.00 79.06  ? 1149 GLN A CG  1 
ATOM   4513 C CD  . GLN A 1 1138 ? 186.836 193.651 193.207 1.00 79.06  ? 1149 GLN A CD  1 
ATOM   4514 O OE1 . GLN A 1 1138 ? 187.676 193.977 194.046 1.00 79.06  ? 1149 GLN A OE1 1 
ATOM   4515 N NE2 . GLN A 1 1138 ? 187.128 192.886 192.162 1.00 79.06  ? 1149 GLN A NE2 1 
ATOM   4516 N N   . PRO A 1 1139 ? 184.688 193.876 198.228 1.00 73.05  ? 1150 PRO A N   1 
ATOM   4517 C CA  . PRO A 1 1139 ? 184.182 194.542 199.429 1.00 73.05  ? 1150 PRO A CA  1 
ATOM   4518 C C   . PRO A 1 1139 ? 184.908 195.856 199.674 1.00 73.05  ? 1150 PRO A C   1 
ATOM   4519 O O   . PRO A 1 1139 ? 185.975 196.128 199.121 1.00 73.05  ? 1150 PRO A O   1 
ATOM   4520 C CB  . PRO A 1 1139 ? 184.467 193.536 200.553 1.00 73.05  ? 1150 PRO A CB  1 
ATOM   4521 C CG  . PRO A 1 1139 ? 185.317 192.440 199.939 1.00 73.05  ? 1150 PRO A CG  1 
ATOM   4522 C CD  . PRO A 1 1139 ? 185.688 192.847 198.547 1.00 73.05  ? 1150 PRO A CD  1 
ATOM   4523 N N   . LEU A 1 1140 ? 184.302 196.679 200.525 1.00 68.46  ? 1151 LEU A N   1 
ATOM   4524 C CA  . LEU A 1 1140 ? 184.877 197.978 200.849 1.00 68.46  ? 1151 LEU A CA  1 
ATOM   4525 C C   . LEU A 1 1140 ? 186.076 197.801 201.771 1.00 68.46  ? 1151 LEU A C   1 
ATOM   4526 O O   . LEU A 1 1140 ? 185.924 197.402 202.930 1.00 68.46  ? 1151 LEU A O   1 
ATOM   4527 C CB  . LEU A 1 1140 ? 183.830 198.875 201.502 1.00 68.46  ? 1151 LEU A CB  1 
ATOM   4528 C CG  . LEU A 1 1140 ? 182.861 199.606 200.575 1.00 68.46  ? 1151 LEU A CG  1 
ATOM   4529 C CD1 . LEU A 1 1140 ? 181.723 198.691 200.155 1.00 68.46  ? 1151 LEU A CD1 1 
ATOM   4530 C CD2 . LEU A 1 1140 ? 182.327 200.847 201.264 1.00 68.46  ? 1151 LEU A CD2 1 
ATOM   4531 N N   . ILE A 1 1141 ? 187.262 198.095 201.258 1.00 68.39  ? 1152 ILE A N   1 
ATOM   4532 C CA  . ILE A 1 1141 ? 188.468 198.059 202.091 1.00 68.39  ? 1152 ILE A CA  1 
ATOM   4533 C C   . ILE A 1 1141 ? 188.399 199.192 203.110 1.00 68.39  ? 1152 ILE A C   1 
ATOM   4534 O O   . ILE A 1 1141 ? 188.031 200.323 202.745 1.00 68.39  ? 1152 ILE A O   1 
ATOM   4535 C CB  . ILE A 1 1141 ? 189.721 198.173 201.219 1.00 68.39  ? 1152 ILE A CB  1 
ATOM   4536 C CG1 . ILE A 1 1141 ? 189.928 196.888 200.415 1.00 68.39  ? 1152 ILE A CG1 1 
ATOM   4537 C CG2 . ILE A 1 1141 ? 190.949 198.463 202.069 1.00 68.39  ? 1152 ILE A CG2 1 
ATOM   4538 C CD1 . ILE A 1 1141 ? 190.028 197.111 198.922 1.00 68.39  ? 1152 ILE A CD1 1 
ATOM   4539 N N   . PRO A 1 1142 ? 188.713 198.945 204.382 1.00 71.10  ? 1153 PRO A N   1 
ATOM   4540 C CA  . PRO A 1 1142 ? 188.678 200.027 205.372 1.00 71.10  ? 1153 PRO A CA  1 
ATOM   4541 C C   . PRO A 1 1142 ? 189.620 201.159 204.989 1.00 71.10  ? 1153 PRO A C   1 
ATOM   4542 O O   . PRO A 1 1142 ? 190.685 200.943 204.408 1.00 71.10  ? 1153 PRO A O   1 
ATOM   4543 C CB  . PRO A 1 1142 ? 189.125 199.340 206.667 1.00 71.10  ? 1153 PRO A CB  1 
ATOM   4544 C CG  . PRO A 1 1142 ? 188.781 197.902 206.464 1.00 71.10  ? 1153 PRO A CG  1 
ATOM   4545 C CD  . PRO A 1 1142 ? 188.989 197.637 205.000 1.00 71.10  ? 1153 PRO A CD  1 
ATOM   4546 N N   . TYR A 1 1143 ? 189.201 202.384 205.318 1.00 67.58  ? 1154 TYR A N   1 
ATOM   4547 C CA  . TYR A 1 1143 ? 189.964 203.562 204.917 1.00 67.58  ? 1154 TYR A CA  1 
ATOM   4548 C C   . TYR A 1 1143 ? 191.357 203.560 205.533 1.00 67.58  ? 1154 TYR A C   1 
ATOM   4549 O O   . TYR A 1 1143 ? 192.332 203.956 204.884 1.00 67.58  ? 1154 TYR A O   1 
ATOM   4550 C CB  . TYR A 1 1143 ? 189.206 204.832 205.301 1.00 67.58  ? 1154 TYR A CB  1 
ATOM   4551 C CG  . TYR A 1 1143 ? 189.800 206.092 204.720 1.00 67.58  ? 1154 TYR A CG  1 
ATOM   4552 C CD1 . TYR A 1 1143 ? 189.977 206.228 203.350 1.00 67.58  ? 1154 TYR A CD1 1 
ATOM   4553 C CD2 . TYR A 1 1143 ? 190.179 207.147 205.537 1.00 67.58  ? 1154 TYR A CD2 1 
ATOM   4554 C CE1 . TYR A 1 1143 ? 190.520 207.375 202.810 1.00 67.58  ? 1154 TYR A CE1 1 
ATOM   4555 C CE2 . TYR A 1 1143 ? 190.721 208.301 205.006 1.00 67.58  ? 1154 TYR A CE2 1 
ATOM   4556 C CZ  . TYR A 1 1143 ? 190.889 208.409 203.641 1.00 67.58  ? 1154 TYR A CZ  1 
ATOM   4557 O OH  . TYR A 1 1143 ? 191.428 209.555 203.104 1.00 67.58  ? 1154 TYR A OH  1 
ATOM   4558 N N   . ALA A 1 1144 ? 191.470 203.123 206.790 1.00 69.05  ? 1155 ALA A N   1 
ATOM   4559 C CA  . ALA A 1 1144 ? 192.780 203.043 207.427 1.00 69.05  ? 1155 ALA A CA  1 
ATOM   4560 C C   . ALA A 1 1144 ? 193.676 202.017 206.747 1.00 69.05  ? 1155 ALA A C   1 
ATOM   4561 O O   . ALA A 1 1144 ? 194.904 202.153 206.771 1.00 69.05  ? 1155 ALA A O   1 
ATOM   4562 C CB  . ALA A 1 1144 ? 192.623 202.709 208.910 1.00 69.05  ? 1155 ALA A CB  1 
ATOM   4563 N N   . ASP A 1 1145 ? 193.087 200.989 206.138 1.00 70.21  ? 1156 ASP A N   1 
ATOM   4564 C CA  . ASP A 1 1145 ? 193.854 199.935 205.488 1.00 70.21  ? 1156 ASP A CA  1 
ATOM   4565 C C   . ASP A 1 1145 ? 194.286 200.294 204.072 1.00 70.21  ? 1156 ASP A C   1 
ATOM   4566 O O   . ASP A 1 1145 ? 194.997 199.504 203.443 1.00 70.21  ? 1156 ASP A O   1 
ATOM   4567 C CB  . ASP A 1 1145 ? 193.044 198.636 205.462 1.00 70.21  ? 1156 ASP A CB  1 
ATOM   4568 C CG  . ASP A 1 1145 ? 192.828 198.058 206.846 1.00 70.21  ? 1156 ASP A CG  1 
ATOM   4569 O OD1 . ASP A 1 1145 ? 193.340 198.643 207.823 1.00 70.21  ? 1156 ASP A OD1 1 
ATOM   4570 O OD2 . ASP A 1 1145 ? 192.146 197.017 206.957 1.00 70.21  ? 1156 ASP A OD2 1 
ATOM   4571 N N   . TRP A 1 1146 ? 193.880 201.450 203.558 1.00 70.62  ? 1157 TRP A N   1 
ATOM   4572 C CA  . TRP A 1 1146 ? 194.264 201.864 202.212 1.00 70.62  ? 1157 TRP A CA  1 
ATOM   4573 C C   . TRP A 1 1146 ? 195.741 202.238 202.152 1.00 70.62  ? 1157 TRP A C   1 
ATOM   4574 O O   . TRP A 1 1146 ? 196.409 202.351 203.180 1.00 70.62  ? 1157 TRP A O   1 
ATOM   4575 C CB  . TRP A 1 1146 ? 193.405 203.040 201.744 1.00 70.62  ? 1157 TRP A CB  1 
ATOM   4576 C CG  . TRP A 1 1146 ? 192.259 202.629 200.873 1.00 70.62  ? 1157 TRP A CG  1 
ATOM   4577 C CD1 . TRP A 1 1146 ? 191.973 201.370 200.437 1.00 70.62  ? 1157 TRP A CD1 1 
ATOM   4578 C CD2 . TRP A 1 1146 ? 191.245 203.482 200.329 1.00 70.62  ? 1157 TRP A CD2 1 
ATOM   4579 N NE1 . TRP A 1 1146 ? 190.842 201.384 199.657 1.00 70.62  ? 1157 TRP A NE1 1 
ATOM   4580 C CE2 . TRP A 1 1146 ? 190.377 202.669 199.574 1.00 70.62  ? 1157 TRP A CE2 1 
ATOM   4581 C CE3 . TRP A 1 1146 ? 190.988 204.854 200.406 1.00 70.62  ? 1157 TRP A CE3 1 
ATOM   4582 C CZ2 . TRP A 1 1146 ? 189.270 203.182 198.903 1.00 70.62  ? 1157 TRP A CZ2 1 
ATOM   4583 C CZ3 . TRP A 1 1146 ? 189.888 205.361 199.739 1.00 70.62  ? 1157 TRP A CZ3 1 
ATOM   4584 C CH2 . TRP A 1 1146 ? 189.043 204.527 198.997 1.00 70.62  ? 1157 TRP A CH2 1 
ATOM   4585 O OXT . TRP A 1 1146 ? 196.302 202.433 201.074 1.00 70.62  ? 1157 TRP A OXT 1 
HETATM 4586 C C2  . BGC B 2 .    ? 189.796 185.362 170.117 1.00 102.63 ? 1    BGC B C2  1 
HETATM 4587 C C3  . BGC B 2 .    ? 190.761 185.731 169.091 1.00 102.63 ? 1    BGC B C3  1 
HETATM 4588 C C4  . BGC B 2 .    ? 191.621 186.869 169.491 1.00 102.63 ? 1    BGC B C4  1 
HETATM 4589 C C5  . BGC B 2 .    ? 192.364 186.559 170.834 1.00 102.63 ? 1    BGC B C5  1 
HETATM 4590 C C6  . BGC B 2 .    ? 193.118 187.695 171.271 1.00 102.63 ? 1    BGC B C6  1 
HETATM 4591 C C1  . BGC B 2 .    ? 190.416 185.115 171.459 1.00 102.63 ? 1    BGC B C1  1 
HETATM 4592 O O1  . BGC B 2 .    ? 189.421 184.990 172.443 1.00 102.63 ? 1    BGC B O1  1 
HETATM 4593 O O2  . BGC B 2 .    ? 189.109 184.126 169.663 1.00 102.63 ? 1    BGC B O2  1 
HETATM 4594 O O3  . BGC B 2 .    ? 189.988 186.066 167.854 1.00 102.63 ? 1    BGC B O3  1 
HETATM 4595 O O4  . BGC B 2 .    ? 192.638 187.140 168.473 1.00 102.63 ? 1    BGC B O4  1 
HETATM 4596 O O5  . BGC B 2 .    ? 191.304 186.207 171.876 1.00 102.63 ? 1    BGC B O5  1 
HETATM 4597 O O6  . BGC B 2 .    ? 193.335 187.614 172.672 1.00 102.63 ? 1    BGC B O6  1 
HETATM 4598 C C2  . BGC B 2 .    ? 192.864 189.478 167.851 1.00 102.63 ? 2    BGC B C2  1 
HETATM 4599 C C3  . BGC B 2 .    ? 192.498 190.532 166.882 1.00 102.63 ? 2    BGC B C3  1 
HETATM 4600 C C4  . BGC B 2 .    ? 192.644 190.162 165.479 1.00 102.63 ? 2    BGC B C4  1 
HETATM 4601 C C5  . BGC B 2 .    ? 192.117 188.718 165.122 1.00 102.63 ? 2    BGC B C5  1 
HETATM 4602 C C6  . BGC B 2 .    ? 192.627 188.325 163.893 1.00 102.63 ? 2    BGC B C6  1 
HETATM 4603 C C1  . BGC B 2 .    ? 192.219 188.156 167.542 1.00 102.63 ? 2    BGC B C1  1 
HETATM 4604 O O2  . BGC B 2 .    ? 192.436 189.941 169.179 1.00 102.63 ? 2    BGC B O2  1 
HETATM 4605 O O3  . BGC B 2 .    ? 193.358 191.713 167.174 1.00 102.63 ? 2    BGC B O3  1 
HETATM 4606 O O4  . BGC B 2 .    ? 191.850 191.104 164.665 1.00 102.63 ? 2    BGC B O4  1 
HETATM 4607 O O5  . BGC B 2 .    ? 192.570 187.717 166.211 1.00 102.63 ? 2    BGC B O5  1 
HETATM 4608 O O6  . BGC B 2 .    ? 193.971 187.948 164.045 1.00 102.63 ? 2    BGC B O6  1 
HETATM 4609 C C2  . BGC B 2 .    ? 192.393 192.296 162.687 1.00 102.63 ? 3    BGC B C2  1 
HETATM 4610 C C3  . BGC B 2 .    ? 193.001 193.532 162.130 1.00 102.63 ? 3    BGC B C3  1 
HETATM 4611 C C4  . BGC B 2 .    ? 192.581 194.754 162.872 1.00 102.63 ? 3    BGC B C4  1 
HETATM 4612 C C5  . BGC B 2 .    ? 192.846 194.616 164.374 1.00 102.63 ? 3    BGC B C5  1 
HETATM 4613 C C6  . BGC B 2 .    ? 192.263 195.798 165.094 1.00 102.63 ? 3    BGC B C6  1 
HETATM 4614 C C1  . BGC B 2 .    ? 192.633 192.156 164.182 1.00 102.63 ? 3    BGC B C1  1 
HETATM 4615 O O2  . BGC B 2 .    ? 192.962 191.160 162.019 1.00 102.63 ? 3    BGC B O2  1 
HETATM 4616 O O3  . BGC B 2 .    ? 192.594 193.654 160.724 1.00 102.63 ? 3    BGC B O3  1 
HETATM 4617 O O4  . BGC B 2 .    ? 193.317 195.892 162.375 1.00 102.63 ? 3    BGC B O4  1 
HETATM 4618 O O5  . BGC B 2 .    ? 192.256 193.388 164.935 1.00 102.63 ? 3    BGC B O5  1 
HETATM 4619 O O6  . BGC B 2 .    ? 190.991 196.101 164.551 1.00 102.63 ? 3    BGC B O6  1 
HETATM 4620 C C2  . BGC B 2 .    ? 193.109 198.067 161.461 1.00 102.63 ? 4    BGC B C2  1 
HETATM 4621 C C3  . BGC B 2 .    ? 192.374 198.947 160.550 1.00 102.63 ? 4    BGC B C3  1 
HETATM 4622 C C4  . BGC B 2 .    ? 192.103 198.322 159.239 1.00 102.63 ? 4    BGC B C4  1 
HETATM 4623 C C5  . BGC B 2 .    ? 191.379 196.945 159.370 1.00 102.63 ? 4    BGC B C5  1 
HETATM 4624 C C6  . BGC B 2 .    ? 191.292 196.324 158.106 1.00 102.63 ? 4    BGC B C6  1 
HETATM 4625 C C1  . BGC B 2 .    ? 192.468 196.724 161.613 1.00 102.63 ? 4    BGC B C1  1 
HETATM 4626 O O2  . BGC B 2 .    ? 193.173 198.707 162.775 1.00 102.63 ? 4    BGC B O2  1 
HETATM 4627 O O3  . BGC B 2 .    ? 193.176 200.177 160.330 1.00 102.63 ? 4    BGC B O3  1 
HETATM 4628 O O4  . BGC B 2 .    ? 191.274 199.190 158.481 1.00 102.63 ? 4    BGC B O4  1 
HETATM 4629 O O5  . BGC B 2 .    ? 192.217 196.075 160.321 1.00 102.63 ? 4    BGC B O5  1 
HETATM 4630 O O6  . BGC B 2 .    ? 190.546 195.126 158.223 1.00 102.63 ? 4    BGC B O6  1 
# 
